Search of human proteins with 4885217

Search of human proteins with 4885217

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4885217 excision repair cross-complementing rodent repair
deficiency, complementation group 4 [Homo sapiens]
         (916 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4885217 excision repair cross-complementing rodent repair def...  1813   0.0  
gi|74959747 Fanconi anemia, complementation group M [Homo sapiens]     60   7e-09
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]            41   0.006
gi|11693132 UPF2 regulator of nonsense transcripts homolog [Homo...    40   0.013
gi|18375676 UPF2 regulator of nonsense transcripts homolog [Homo...    40   0.013
gi|104526627 triadin [Homo sapiens]                                    40   0.013
gi|56676397 ankyrin repeat domain 11 [Homo sapiens]                    39   0.017
gi|30089962 CDC42-binding protein kinase alpha isoform B [Homo s...    39   0.022
gi|12711676 UPF3 regulator of nonsense transcripts homolog A iso...    38   0.038
gi|239750213 PREDICTED: hypothetical protein [Homo sapiens]            38   0.049
gi|239508778 PREDICTED: hypothetical protein, partial [Homo sapi...    37   0.065
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa...    37   0.065
gi|50348611 mitochondrial tumor suppressor 1 isoform 1 [Homo sap...    37   0.084
gi|50348617 mitochondrial tumor suppressor 1 isoform 2 [Homo sap...    37   0.084
gi|50348626 mitochondrial tumor suppressor 1 isoform 4 [Homo sap...    37   0.084
gi|239050813 lipoxygenase homology domains 1 isoform 1 [Homo sap...    37   0.084
gi|115648142 centrosomal protein 164kDa [Homo sapiens]                 37   0.084
gi|155030242 WD repeat domain 60 [Homo sapiens]                        37   0.084
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]     37   0.084
gi|81295816 nasopharyngeal epithelium specific protein 1 [Homo s...    37   0.084
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li...    37   0.11 
gi|192807336 arsenate resistance protein 2 isoform e [Homo sapiens]    37   0.11 
gi|192807332 arsenate resistance protein 2 isoform c [Homo sapiens]    37   0.11 
gi|71061468 centromere protein E [Homo sapiens]                        37   0.11 
gi|91176325 bromodomain adjacent to zinc finger domain, 2A [Homo...    37   0.11 
gi|12711674 UPF3 regulator of nonsense transcripts homolog B iso...    36   0.14 
gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]            36   0.19 
gi|94681063 bromodomain adjacent to zinc finger domain, 2B [Homo...    36   0.19 
gi|117553580 adaptor-related protein complex 3, delta 1 subunit ...    35   0.25 
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]     35   0.25 

>gi|4885217 excision repair cross-complementing rodent repair
           deficiency, complementation group 4 [Homo sapiens]
          Length = 916

 Score = 1813 bits (4696), Expect = 0.0
 Identities = 916/916 (100%), Positives = 916/916 (100%)

Query: 1   MESGQPARRIAMAPLLEYERQLVLELLDTDGLVVCARGLGADRLLYHFLQLHCHPACLVL 60
           MESGQPARRIAMAPLLEYERQLVLELLDTDGLVVCARGLGADRLLYHFLQLHCHPACLVL
Sbjct: 1   MESGQPARRIAMAPLLEYERQLVLELLDTDGLVVCARGLGADRLLYHFLQLHCHPACLVL 60

Query: 61  VLNTQPAEEEYFINQLKIEGVEHLPRRVTNEITSNSRYEVYTQGGVIFATSRILVVDFLT 120
           VLNTQPAEEEYFINQLKIEGVEHLPRRVTNEITSNSRYEVYTQGGVIFATSRILVVDFLT
Sbjct: 61  VLNTQPAEEEYFINQLKIEGVEHLPRRVTNEITSNSRYEVYTQGGVIFATSRILVVDFLT 120

Query: 121 DRIPSDLITGILVYRAHRIIESCQEAFILRLFRQKNKRGFIKAFTDNAVAFDTGFCHVER 180
           DRIPSDLITGILVYRAHRIIESCQEAFILRLFRQKNKRGFIKAFTDNAVAFDTGFCHVER
Sbjct: 121 DRIPSDLITGILVYRAHRIIESCQEAFILRLFRQKNKRGFIKAFTDNAVAFDTGFCHVER 180

Query: 181 VMRNLFVRKLYLWPRFHVAVNSFLEQHKPEVVEIHVSMTPTMLAIQTAILDILNACLKEL 240
           VMRNLFVRKLYLWPRFHVAVNSFLEQHKPEVVEIHVSMTPTMLAIQTAILDILNACLKEL
Sbjct: 181 VMRNLFVRKLYLWPRFHVAVNSFLEQHKPEVVEIHVSMTPTMLAIQTAILDILNACLKEL 240

Query: 241 KCHNPSLEVEDLSLENAIGKPFDKTIRHYLDPLWHQLGAKTKSLVQDLKILRTLLQYLSQ 300
           KCHNPSLEVEDLSLENAIGKPFDKTIRHYLDPLWHQLGAKTKSLVQDLKILRTLLQYLSQ
Sbjct: 241 KCHNPSLEVEDLSLENAIGKPFDKTIRHYLDPLWHQLGAKTKSLVQDLKILRTLLQYLSQ 300

Query: 301 YDCVTFLNLLESLRATEKAFGQNSGWLFLDSSTSMFINARARVYHLPDAKMSKKEKISEK 360
           YDCVTFLNLLESLRATEKAFGQNSGWLFLDSSTSMFINARARVYHLPDAKMSKKEKISEK
Sbjct: 301 YDCVTFLNLLESLRATEKAFGQNSGWLFLDSSTSMFINARARVYHLPDAKMSKKEKISEK 360

Query: 361 MEIKEGEETKKELVLESNPKWEALTEVLKEIEAENKESEALGGPGQVLICASDDRTCSQL 420
           MEIKEGEETKKELVLESNPKWEALTEVLKEIEAENKESEALGGPGQVLICASDDRTCSQL
Sbjct: 361 MEIKEGEETKKELVLESNPKWEALTEVLKEIEAENKESEALGGPGQVLICASDDRTCSQL 420

Query: 421 RDYITLGAEAFLLRLYRKTFEKDSKAEEVWMKFRKEDSSKRIRKSHKRPKDPQNKERAST 480
           RDYITLGAEAFLLRLYRKTFEKDSKAEEVWMKFRKEDSSKRIRKSHKRPKDPQNKERAST
Sbjct: 421 RDYITLGAEAFLLRLYRKTFEKDSKAEEVWMKFRKEDSSKRIRKSHKRPKDPQNKERAST 480

Query: 481 KERTLKKKKRKLTLTQMVGKPEELEEEGDVEEGYRREISSSPESCPEEIKHEEFDVNLSS 540
           KERTLKKKKRKLTLTQMVGKPEELEEEGDVEEGYRREISSSPESCPEEIKHEEFDVNLSS
Sbjct: 481 KERTLKKKKRKLTLTQMVGKPEELEEEGDVEEGYRREISSSPESCPEEIKHEEFDVNLSS 540

Query: 541 DAAFGILKEPLTIIHPLLGCSDPYALTRVLHEVEPRYVVLYDAELTFVRQLEIYRASRPG 600
           DAAFGILKEPLTIIHPLLGCSDPYALTRVLHEVEPRYVVLYDAELTFVRQLEIYRASRPG
Sbjct: 541 DAAFGILKEPLTIIHPLLGCSDPYALTRVLHEVEPRYVVLYDAELTFVRQLEIYRASRPG 600

Query: 601 KPLRVYFLIYGGSTEEQRYLTALRKEKEAFEKLIREKASMVVPEEREGRDETNLDLVRGT 660
           KPLRVYFLIYGGSTEEQRYLTALRKEKEAFEKLIREKASMVVPEEREGRDETNLDLVRGT
Sbjct: 601 KPLRVYFLIYGGSTEEQRYLTALRKEKEAFEKLIREKASMVVPEEREGRDETNLDLVRGT 660

Query: 661 ASADVSTDTRKAGGQEQNGTQQSIVVDMREFRSELPSLIHRRGIDIEPVTLEVGDYILTP 720
           ASADVSTDTRKAGGQEQNGTQQSIVVDMREFRSELPSLIHRRGIDIEPVTLEVGDYILTP
Sbjct: 661 ASADVSTDTRKAGGQEQNGTQQSIVVDMREFRSELPSLIHRRGIDIEPVTLEVGDYILTP 720

Query: 721 EMCVERKSISDLIGSLNNGRLYSQCISMSRYYKRPVLLIEFDPSKPFSLTSRGALFQEIS 780
           EMCVERKSISDLIGSLNNGRLYSQCISMSRYYKRPVLLIEFDPSKPFSLTSRGALFQEIS
Sbjct: 721 EMCVERKSISDLIGSLNNGRLYSQCISMSRYYKRPVLLIEFDPSKPFSLTSRGALFQEIS 780

Query: 781 SNDISSKLTLLTLHFPRLRILWCPSPHATAELFEELKQSKPQPDAATALAITADSETLPE 840
           SNDISSKLTLLTLHFPRLRILWCPSPHATAELFEELKQSKPQPDAATALAITADSETLPE
Sbjct: 781 SNDISSKLTLLTLHFPRLRILWCPSPHATAELFEELKQSKPQPDAATALAITADSETLPE 840

Query: 841 SEKYNPGPQDFLLKMPGVNAKNCRSLMHHVKNIAELAALSQDELTSILGNAANAKQLYDF 900
           SEKYNPGPQDFLLKMPGVNAKNCRSLMHHVKNIAELAALSQDELTSILGNAANAKQLYDF
Sbjct: 841 SEKYNPGPQDFLLKMPGVNAKNCRSLMHHVKNIAELAALSQDELTSILGNAANAKQLYDF 900

Query: 901 IHTSFAEVVSKGKGKK 916
           IHTSFAEVVSKGKGKK
Sbjct: 901 IHTSFAEVVSKGKGKK 916


>gi|74959747 Fanconi anemia, complementation group M [Homo sapiens]
          Length = 2048

 Score = 60.5 bits (145), Expect = 7e-09
 Identities = 59/233 (25%), Positives = 103/233 (44%), Gaps = 19/233 (8%)

Query: 677  QNGTQQSIVVDMREFRSELPSLIHRR---GIDIEPVTLEVGDYILTPEMCVERKSISDLI 733
            Q G    I+V   E  S L  +   R   G+ +E   L   DYI++  M VER+S S+++
Sbjct: 1813 QEGKGTCILVGGHEITSGLEVISSLRAIHGLQVEVCPLNGCDYIVSNRMVVERRSQSEML 1872

Query: 734  GSLNNGRLYSQCISMSRYYKRPVLLIEFDPSKPFSLTSRGALFQEISSNDISSKLTLLTL 793
             S+N  +   Q   +   ++R  +++E D  K    TSR  +F+   S D      L TL
Sbjct: 1873 NSVNKNKFIEQIQHLQSMFERICVIVEKDREKTGD-TSR--MFRRTKSYD----SLLTTL 1925

Query: 794  HFPRLRILWCPSPHATAELFEELKQSKPQPDAATALAITADSETLPESEKYNPGPQDFLL 853
                +RIL+      TA+L +EL   + + +    +    +S    +SE        F L
Sbjct: 1926 IGAGIRILFSSCQEETADLLKELSLVEQRKNVGIHVPTVVNSN---KSEAL-----QFYL 1977

Query: 854  KMPGVNAKNCRSLMHHVKNIAELAALSQDELTSILG-NAANAKQLYDFIHTSF 905
             +P ++     ++ H   ++  +A  S  E++         A+++Y +IH  F
Sbjct: 1978 SIPNISYITALNMCHQFSSVKRMANSSLQEISMYAQVTHQKAEEIYRYIHYVF 2030



 Score = 37.0 bits (84), Expect = 0.084
 Identities = 46/233 (19%), Positives = 102/233 (43%), Gaps = 13/233 (5%)

Query: 14  PLLEYERQLVLELLDTDGLVVCARGLG----ADRLLYHFLQLHCHPACLVLVLNTQPAEE 69
           P+ +Y+  +    L  + LV    GLG    A  ++Y+F +       +V +  T+P   
Sbjct: 90  PVRDYQLHISRAALFCNTLVCLPTGLGKTFIAAVVMYNFYRWF-PSGKVVFMAPTKPLVT 148

Query: 70  EYFINQLKIEGV--EHLPRRVTNEITSNSRYEVYTQGGVIFATSRILVVDFLTDRIPSDL 127
           +      ++ G+   H+   +T    +++R E++    V+F T +++V D      P+  
Sbjct: 149 QQIEACYQVMGIPQSHMAE-MTGSTQASTRKEIWCSKRVLFLTPQVMVNDLSRGACPAAE 207

Query: 128 ITGILVYRAHRIIESCQEAFILRLFRQKNKRGFIKAFTDNAVAFDTGFCHVERVMRNLFV 187
           I  +++  AH+ + +     ++R   +      I A +       +    V++V+ NL +
Sbjct: 208 IKCLVIDEAHKALGNYAYCQVVRELVKYTNHFRILALSATP---GSDIKAVQQVITNLLI 264

Query: 188 RKLYLWPRFHVAVNSFLEQHKPEVVEIHVSMTPTMLAIQTAILDILNACLKEL 240
            ++ L  R   + +     H+ +V ++ V +   + AIQ   + IL +  + L
Sbjct: 265 GQIEL--RSEDSPDILTYSHERKVEKLIVPLGEELAAIQKTYIQILESFARSL 315


>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 245

 Score = 40.8 bits (94), Expect = 0.006
 Identities = 27/81 (33%), Positives = 40/81 (49%), Gaps = 1/81 (1%)

Query: 437 RKTFEKDSKAEEVWMKFRKEDSSKRIRKSHKRPKDPQNKERASTKERTLKKKKRKLTLTQ 496
           RK   +  +  E   K +K +  K  R+  KR ++ +NKE    KE+  KK+K++   T 
Sbjct: 69  RKREREKERKRERGKKEKKGERKKEERERKKRRREKENKE-GEEKEKRKKKEKKERGRTS 127

Query: 497 MVGKPEELEEEGDVEEGYRRE 517
             GK  E +EE   EE   RE
Sbjct: 128 KEGKERERKEERKREERKERE 148



 Score = 39.7 bits (91), Expect = 0.013
 Identities = 46/179 (25%), Positives = 76/179 (42%), Gaps = 28/179 (15%)

Query: 340 RARVYHLPDAKMSKKEKISE-KMEIKEGEETKKELVLESNPKWEALTEVLKEIEAENKES 398
           R R   +   K  KKE+ SE K E +E E+ K+E   E   +        KE + E K+ 
Sbjct: 39  REREREIETRKEGKKERESERKKERREREKRKREREKERKRE-----RGKKEKKGERKKE 93

Query: 399 EALGGPGQVLICASDDRTCSQLRDYITLGAEAFLLRLYRKTFEKDSKAEEVWMKFRKEDS 458
           E                   + R+      E    R  ++  E+   ++E   + RKE+ 
Sbjct: 94  ER--------------ERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEER 139

Query: 459 SKRIRKSHKRPKDPQNKERASTKERTLKKKKRKLTLTQMVGKPEELEEEGDVEEGYRRE 517
            +  RK  +R K+ + KER        ++K+RK    + VG+ EE  +E + +E  +RE
Sbjct: 140 KREERKERERKKEEREKER--------ERKERKKRERKQVGEKEEERKEKERKERKKRE 190



 Score = 33.1 bits (74), Expect = 1.2
 Identities = 39/142 (27%), Positives = 57/142 (40%), Gaps = 36/142 (25%)

Query: 350 KMSKKEKISEKMEIKEGEETKKELVLESNPKWEALTEVLKEIEAENKESEALGGPGQVLI 409
           K  KKEK       KEG+E ++        K E   E  KE E + +E E          
Sbjct: 114 KRKKKEKKERGRTSKEGKERER--------KEERKREERKERERKKEEREK--------- 156

Query: 410 CASDDRTCSQLRDYITLGAEAFLLRLYRKTFEKDSKAEEVWMKFRKEDSSKRIRKSHKRP 469
               +R   + R+   +G             EK+ + +E   K RK    KR R   +R 
Sbjct: 157 --ERERKERKKRERKQVG-------------EKEEERKEKERKERK----KRERNRKERK 197

Query: 470 KDPQNKERASTKERTLKKKKRK 491
           K+ + KER   K+   KK++RK
Sbjct: 198 KERERKERRERKKERKKKEERK 219



 Score = 31.2 bits (69), Expect = 4.6
 Identities = 23/97 (23%), Positives = 42/97 (43%), Gaps = 1/97 (1%)

Query: 437 RKTFEKDSKAEEVWMKFRKEDSSKRIRKSHKRPKDPQNKERASTKERTLKKKKRKLTLTQ 496
           RK  +K+ ++E    +  +E   +   K  KR +  + K+    KE   +KK+R+     
Sbjct: 48  RKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRR-EKEN 106

Query: 497 MVGKPEELEEEGDVEEGYRREISSSPESCPEEIKHEE 533
             G+ +E  ++ + +E  R           EE K EE
Sbjct: 107 KEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREE 143


>gi|11693132 UPF2 regulator of nonsense transcripts homolog [Homo
           sapiens]
          Length = 1272

 Score = 39.7 bits (91), Expect = 0.013
 Identities = 26/108 (24%), Positives = 49/108 (45%), Gaps = 6/108 (5%)

Query: 437 RKTFEKDSKAEEVWMKFRKEDSSKRIRKSHKRPKDPQNKERASTKERTLKKKKRKLTLTQ 496
           +K  E+  KAEE   K  +E+  K   +  K+ ++   +++       +K+K+  + L Q
Sbjct: 73  KKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMKEKEESIQLHQ 132

Query: 497 MVGKPEELEEEGDVEEGYRREISSSPESCPEEIKHEEFDVNLSSDAAF 544
              +   L +E       R +  ++P+S PEE      D +L  + AF
Sbjct: 133 EAWERHHLRKE------LRSKNQNAPDSRPEENFFSRLDSSLKKNTAF 174



 Score = 30.8 bits (68), Expect = 6.0
 Identities = 22/82 (26%), Positives = 42/82 (51%), Gaps = 7/82 (8%)

Query: 459 SKRIRKSHKRPKD--PQNKERASTKERTLKKKKR-----KLTLTQMVGKPEELEEEGDVE 511
           ++R + +    KD  P NKE+  ++ RT+  K+R     KLT  + V K  E +++   +
Sbjct: 3   AERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLED 62

Query: 512 EGYRREISSSPESCPEEIKHEE 533
           +  ++E     +   E++K EE
Sbjct: 63  DKRKKEDKERKKKDEEKVKAEE 84



 Score = 30.8 bits (68), Expect = 6.0
 Identities = 20/87 (22%), Positives = 40/87 (45%), Gaps = 6/87 (6%)

Query: 456 EDSSKRIRKSHKRPKDPQNKERASTKERTLKKKKRKLTLTQMVGKPEELEEEGDVEEGYR 515
           ED  KR+    ++ +D + K++   K +  ++ K+K    +   K  + EE    EE  +
Sbjct: 54  EDKKKRLEDDKRKKEDKERKKKDEEKVKAEEESKKK---EEEEKKKHQEEERKKQEEQAK 110

Query: 516 REISSSPESCPEEIKHEEFDVNLSSDA 542
           R+     E    ++K +E  + L  +A
Sbjct: 111 RQ---QEEEAAAQMKEKEESIQLHQEA 134



 Score = 30.4 bits (67), Expect = 7.9
 Identities = 23/79 (29%), Positives = 38/79 (48%), Gaps = 2/79 (2%)

Query: 455 KEDSSKRIRKSHKRPKDPQNKERASTKERTLKKKKRKLTLTQMVGKPEELEEEGDVEEGY 514
           K+ S +R   S +RPKD  + +  + KE +   + +K  L     K E+ E +   EE  
Sbjct: 23  KDCSERRTVSSKERPKD--DIKLTAKKEVSKAPEDKKKRLEDDKRKKEDKERKKKDEEKV 80

Query: 515 RREISSSPESCPEEIKHEE 533
           + E  S  +   E+ KH+E
Sbjct: 81  KAEEESKKKEEEEKKKHQE 99


>gi|18375676 UPF2 regulator of nonsense transcripts homolog [Homo
           sapiens]
          Length = 1272

 Score = 39.7 bits (91), Expect = 0.013
 Identities = 26/108 (24%), Positives = 49/108 (45%), Gaps = 6/108 (5%)

Query: 437 RKTFEKDSKAEEVWMKFRKEDSSKRIRKSHKRPKDPQNKERASTKERTLKKKKRKLTLTQ 496
           +K  E+  KAEE   K  +E+  K   +  K+ ++   +++       +K+K+  + L Q
Sbjct: 73  KKKDEEKVKAEEESKKKEEEEKKKHQEEERKKQEEQAKRQQEEEAAAQMKEKEESIQLHQ 132

Query: 497 MVGKPEELEEEGDVEEGYRREISSSPESCPEEIKHEEFDVNLSSDAAF 544
              +   L +E       R +  ++P+S PEE      D +L  + AF
Sbjct: 133 EAWERHHLRKE------LRSKNQNAPDSRPEENFFSRLDSSLKKNTAF 174



 Score = 30.8 bits (68), Expect = 6.0
 Identities = 22/82 (26%), Positives = 42/82 (51%), Gaps = 7/82 (8%)

Query: 459 SKRIRKSHKRPKD--PQNKERASTKERTLKKKKR-----KLTLTQMVGKPEELEEEGDVE 511
           ++R + +    KD  P NKE+  ++ RT+  K+R     KLT  + V K  E +++   +
Sbjct: 3   AERKKPASMEEKDSLPNNKEKDCSERRTVSSKERPKDDIKLTAKKEVSKAPEDKKKRLED 62

Query: 512 EGYRREISSSPESCPEEIKHEE 533
           +  ++E     +   E++K EE
Sbjct: 63  DKRKKEDKERKKKDEEKVKAEE 84



 Score = 30.8 bits (68), Expect = 6.0
 Identities = 20/87 (22%), Positives = 40/87 (45%), Gaps = 6/87 (6%)

Query: 456 EDSSKRIRKSHKRPKDPQNKERASTKERTLKKKKRKLTLTQMVGKPEELEEEGDVEEGYR 515
           ED  KR+    ++ +D + K++   K +  ++ K+K    +   K  + EE    EE  +
Sbjct: 54  EDKKKRLEDDKRKKEDKERKKKDEEKVKAEEESKKK---EEEEKKKHQEEERKKQEEQAK 110

Query: 516 REISSSPESCPEEIKHEEFDVNLSSDA 542
           R+     E    ++K +E  + L  +A
Sbjct: 111 RQ---QEEEAAAQMKEKEESIQLHQEA 134



 Score = 30.4 bits (67), Expect = 7.9
 Identities = 23/79 (29%), Positives = 38/79 (48%), Gaps = 2/79 (2%)

Query: 455 KEDSSKRIRKSHKRPKDPQNKERASTKERTLKKKKRKLTLTQMVGKPEELEEEGDVEEGY 514
           K+ S +R   S +RPKD  + +  + KE +   + +K  L     K E+ E +   EE  
Sbjct: 23  KDCSERRTVSSKERPKD--DIKLTAKKEVSKAPEDKKKRLEDDKRKKEDKERKKKDEEKV 80

Query: 515 RREISSSPESCPEEIKHEE 533
           + E  S  +   E+ KH+E
Sbjct: 81  KAEEESKKKEEEEKKKHQE 99


>gi|104526627 triadin [Homo sapiens]
          Length = 729

 Score = 39.7 bits (91), Expect = 0.013
 Identities = 53/214 (24%), Positives = 90/214 (42%), Gaps = 35/214 (16%)

Query: 346 LPDAKMSKKEKISEKMEIKEGEETKKELVLESNPKWEALTEVLKEIEAENKESEALGGPG 405
           LP  + S+    S  +E KEGE+ K E  + S  K +   ++ K+ E E         PG
Sbjct: 294 LPTEQASRPTPASPALEEKEGEKKKAEKKVTSETKKKEKEDIKKKSEKETAIDVEKKEPG 353

Query: 406 QVLICASDDRTCSQLRDYITLGAEAFLLRLYRKTFEKDSK--AEEVWMKFRKEDS----- 458
           +    AS+ +     +  + + A+A   +  +K   K +K  AE    K +K++      
Sbjct: 354 K----ASETK-----QGTVKIAAQAAAKKDEKKEDSKKTKKPAEVEQPKGKKQEKKEKHV 404

Query: 459 --SKRIRKSHKRPKDPQNK---ERA-------STKERTLKKKKRKLTLT-------QMVG 499
             +K  +K H  P D Q K   ERA       S K+    KK+ K T T       +  G
Sbjct: 405 EPAKSPKKEHSVPSDKQVKAKTERAKEEIGAVSIKKAVPGKKEEKTTKTVEQEIRKEKSG 464

Query: 500 KPEELEEEGDVEEGYRREISSSPESCPEEIKHEE 533
           K   + ++ +  +G   ++ +S +    E K +E
Sbjct: 465 KTSSILKDKEPIKGKEEKVPASLKEKEPETKKDE 498



 Score = 33.9 bits (76), Expect = 0.71
 Identities = 46/230 (20%), Positives = 89/230 (38%), Gaps = 32/230 (13%)

Query: 455 KEDSSKRIRKSHKRPKDPQNKERASTKE----RTLKKKKRKLTLTQMVGKPEELEEEGDV 510
           KE   +++R+  K  K   +KE+   KE    +TL K+++K    +   +  + E +G  
Sbjct: 167 KEKGKEKVREKEKPEKKATHKEKIEKKEKPETKTLAKEQKKAKTAEKSEEKTKKEVKGGK 226

Query: 511 EEGYR------REISSSPESCPEEIKHEEFDVNLSSDAAFGILKEPLTIIHPLLGCSDPY 564
           +E  +      +E+  +P    E+   E+  V+                        D Y
Sbjct: 227 QEKVKQTAAKVKEVQKTPSKPKEKEDKEKAAVSKHEQ-------------------KDQY 267

Query: 565 ALTRVLHEVEPRYVVLYDAELTFVRQLEIYRASRPGKPLRVYFLIYGGSTEEQRYLTA-- 622
           A  R + ++     +           L   +ASRP           G   + ++ +T+  
Sbjct: 268 AFCRYMIDIFVHGDLKPGQSPAIPPPLPTEQASRPTPASPALEEKEGEKKKAEKKVTSET 327

Query: 623 LRKEKEAFEKLIREKASMVVPEEREGR-DETNLDLVRGTASADVSTDTRK 671
            +KEKE  +K   ++ ++ V ++  G+  ET    V+  A A    D +K
Sbjct: 328 KKKEKEDIKKKSEKETAIDVEKKEPGKASETKQGTVKIAAQAAAKKDEKK 377



 Score = 33.5 bits (75), Expect = 0.93
 Identities = 40/189 (21%), Positives = 80/189 (42%), Gaps = 16/189 (8%)

Query: 348 DAKMSKKEKISEKMEIKEGEETKKELVLESNPKWEALTEVLKEIEAENKES-EALGGPG- 405
           D+K +KK    E+ + K+ E+ +K +    +PK E      K+++A+ + + E +G    
Sbjct: 379 DSKKTKKPAEVEQPKGKKQEKKEKHVEPAKSPKKEHSVPSDKQVKAKTERAKEEIGAVSI 438

Query: 406 -QVLICASDDRTCSQLRDYITLGAEAFLLRLYRKTFEKDSKAEEVWMKFR-KEDSSKRIR 463
            + +    +++T   +   I          + +       K E+V    + KE  +K+  
Sbjct: 439 KKAVPGKKEEKTTKTVEQEIRKEKSGKTSSILKDKEPIKGKEEKVPASLKEKEPETKKDE 498

Query: 464 KSHK-----RPKDPQNKERASTKERTLKKKKRKLTLTQMVG-------KPEELEEEGDVE 511
           K  K     +PK PQ + +   K     KK+ K  +++ V        KPE+    G  E
Sbjct: 499 KMSKAGKEVKPKPPQLQGKKEEKPEPQIKKEAKPAISEKVQIHKQDIVKPEKTVSHGKPE 558

Query: 512 EGYRREISS 520
           E   +++ +
Sbjct: 559 EKVLKQVKA 567


>gi|56676397 ankyrin repeat domain 11 [Homo sapiens]
          Length = 2663

 Score = 39.3 bits (90), Expect = 0.017
 Identities = 67/290 (23%), Positives = 123/290 (42%), Gaps = 48/290 (16%)

Query: 263 DKTIRHYLDPLWHQLGAKTKSLVQDLKILRTLLQYLSQYDCVTFLNLLESLRATEKAFGQ 322
           D+  +H+    W  + +   S V  L    T  +  S+ D  +  + +ESL+   K    
Sbjct: 540 DQHTKHWRTDNWKTISSPAWSEVSSLSD-STRTRLTSESDYSSEGSSVESLKPVRKRQEH 598

Query: 323 NSGWLFLDSSTSMFINARARVYHLP-DAKMSKKEKISEKMEIKEGEETKKELVLESNPKW 381
                  +  +    +A   V  L  + K+ KK K   K + KE    K +  +    K 
Sbjct: 599 RKRASLSEKKSPFLSSAEGAVPKLDKEGKVVKKHKTKHKHKNKE----KGQCSISQELKL 654

Query: 382 EALTEVLKEIEAENKESEALGGPGQVLICASDDRTCSQLRDYITLGAEAFLLRLYRKTFE 441
           ++ T    E E   ++S+      + ++  +D  T ++L+          +L+  R  F+
Sbjct: 655 KSFTY---EYEDSKQKSD------KAILLENDLSTENKLK----------VLKHDRDHFK 695

Query: 442 KDSKA------EEVWMKFRKEDSSKRIR-------KSHKRPKDPQNK--ERASTKERTLK 486
           K+ K       E+ W+ F+ E S KRI+       +S +  KD  NK  +  S KE++ K
Sbjct: 696 KEEKLSKMKLEEKEWL-FKDEKSLKRIKDTNKDISRSFREEKDRSNKAEKERSLKEKSPK 754

Query: 487 KKKRKLTLTQMVGK----PEELEEEGDVEEGYRREISSSPESCPEEIKHE 532
           ++K +L   +   K    P +LE++ D++E    +IS   E   +E K +
Sbjct: 755 EEKLRLYKEERKKKSKDRPSKLEKKNDLKED---KISKEKEKIFKEDKEK 801



 Score = 35.0 bits (79), Expect = 0.32
 Identities = 60/235 (25%), Positives = 93/235 (39%), Gaps = 36/235 (15%)

Query: 348  DAKMSKKEKISEKMEIKEGEETKKELVLESNPKWEALTEVLKEIEAENKESEALGGPGQV 407
            D K  K  K  EK+  ++ E+ KKE V   +  ++      K    EN++++      Q 
Sbjct: 781  DLKEDKISKEKEKIFKEDKEKLKKEKVYREDSAFDEYCN--KNQFLENEDTKFSLSDDQR 838

Query: 408  LICASD-----------DRTCSQLRDYITLGAEAFLLRLYRKTFEKDSKAEEVWMKFRKE 456
                SD           D   S + DY  + +++ + +L  +T ++DSK        R+ 
Sbjct: 839  DRWFSDLSDSSFDFKGEDSWDSPVTDYRDMKSDS-VAKLILETVKEDSKE-------RRR 890

Query: 457  DSSKRIRKSHKRP------KDPQNKERASTKERTLKKKKRKLTLTQMVGKPEELEEEG-- 508
            DS  R ++ ++ P      +D  +K     KE+T K K     L++   K  E  E G  
Sbjct: 891  DSRAREKRDYREPFFRKKDRDYLDKNSEKRKEQTEKHKSVPGYLSEKDKKRRESAEAGRD 950

Query: 509  --DVEEG--YRREISSSPESCPEEIKHE---EFDVNLSSDAAFGILKEPLTIIHP 556
              D  E    RR+  + PE    E   E   E      SD  FG   EP    HP
Sbjct: 951  RKDALESCKERRDGRAKPEEAHREELKECGCESGFKDKSDGDFGKGLEPWERHHP 1005


>gi|30089962 CDC42-binding protein kinase alpha isoform B [Homo
           sapiens]
          Length = 1719

 Score = 38.9 bits (89), Expect = 0.022
 Identities = 82/346 (23%), Positives = 134/346 (38%), Gaps = 60/346 (17%)

Query: 204 LEQHKPEVVEIHVSMTPTMLAIQTAILDILNACLKELKCHNPSLEVEDLSLENAIGKPFD 263
           LEQ K E+       T T+ A+Q + +D      K+L+  N   E+E L  +       +
Sbjct: 451 LEQEKLELSRKLQESTQTVQALQYSTVDGPLTASKDLEIKNLKEEIEKLRKQVTESSHLE 510

Query: 264 K------TIRHYLDPLWHQLGAKTKSLVQDLKILRTLLQYLSQYDCVTFLNLLESLRATE 317
           +       +R  LD  + Q+ A  K        ++TL Q     +    +   E L+   
Sbjct: 511 QQLEEANAVRQELDDAFRQIKAYEKQ-------IKTLQQEREDLN-KELVQASERLKNQS 562

Query: 318 KAFGQNSGWLFLDSSTSMFINARARVYHLPDAKMSKKEKISEKMEIKEGEETKKELVLES 377
           K          L     M IN R    H      ++K+K++  +  KE E    +LV++ 
Sbjct: 563 KELKDAHCQRKLAMQEFMEINERLTELH------TQKQKLARHVRDKEEE---VDLVMQ- 612

Query: 378 NPKWEALTEVLKEIEAENKE----SEALGGPGQVLICASDDRTCSQLRDYITLGAEAFLL 433
             K E+L + L+  E   KE    +EAL         AS DR   +  ++ +   E  L 
Sbjct: 613 --KVESLRQELRRTERAKKELEVHTEALAAE------ASKDRKLREQSEHYSKQLENELE 664

Query: 434 RLYRKTFEK-------DSKAEEVWMK--------FRKEDSSKR-------IRKSHKRPKD 471
            L +K           + + E   +K        F +E+ SKR       I+   K   D
Sbjct: 665 GLKQKQISYSPGVCSIEHQQEITKLKTDLEKKSIFYEEELSKREGIHANEIKNLKKELHD 724

Query: 472 PQNKERASTKERTLKKKKRKLTLTQMVGKPEELEEEGDVEEGYRRE 517
            + ++ A  KE  + K K + T  +   + EE E E   ++ Y RE
Sbjct: 725 SEGQQLALNKEIMILKDKLEKTRRESQSEREEFESE--FKQQYERE 768


>gi|12711676 UPF3 regulator of nonsense transcripts homolog A
           isoform hUpf3p [Homo sapiens]
          Length = 476

 Score = 38.1 bits (87), Expect = 0.038
 Identities = 49/204 (24%), Positives = 88/204 (43%), Gaps = 24/204 (11%)

Query: 325 GWLFLDSSTSMFINARARVYHLPDAKMSKKEKISEKMEIKEGEETKKELVLESNPKWEAL 384
           G++FLDS     +   A V   P  K++KK+    K + K G        +E +P+++  
Sbjct: 133 GYIFLDSKG---LEYPAVVEFAPFQKIAKKKL--RKKDAKTGS-------IEDDPEYK-- 178

Query: 385 TEVLKEIEAENKESEALGGPGQVLICASDDRTCSQLRDYITLGAEAFLLRLYRKTFEKDS 444
               K +E    E E      + L+   + +T   +    T   E    R   K   ++ 
Sbjct: 179 ----KFLETYCVEEEKTSANPETLLGEMEAKTRELIARRTTPLLEYIKNRKLEKQRIREE 234

Query: 445 KAEEVWMKFRKEDSSKRIRKSHKRPK--DPQNKERASTKERTLKKKKRKLTLTQMVGKPE 502
           K EE   + R+E   KR+R+  KR +  + + K++ + K++ + +K+ ++ L +   K E
Sbjct: 235 KREE---RRRRELEKKRLREEEKRRRREEERCKKKETDKQKKIAEKEVRIKLLKKPEKGE 291

Query: 503 ELEEEGDVEEGYRREI-SSSPESC 525
           E   E   E G   +      ESC
Sbjct: 292 EPTTEKPKERGEEIDTGGGKQESC 315


>gi|239750213 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 248

 Score = 37.7 bits (86), Expect = 0.049
 Identities = 22/90 (24%), Positives = 45/90 (50%), Gaps = 3/90 (3%)

Query: 444 SKAEEVWMKFRKEDSSKRIRKSHKRPKDPQNKERASTKERTLKKKKRKLTLTQMVGKPEE 503
           ++ E  W + RK+ ++K   K  K+    + K++ +TK++T  K K++ T T+       
Sbjct: 17  TEKESAWKRGRKKKTTK---KKKKKKTTMKKKKKTTTKKKTTTKTKKRTTTTKKTTTTTT 73

Query: 504 LEEEGDVEEGYRREISSSPESCPEEIKHEE 533
            E+E + E+   +E     E   E+ K ++
Sbjct: 74  KEKEKEKEKEKEKEKEKEKEKEKEKKKKKK 103


>gi|239508778 PREDICTED: hypothetical protein, partial [Homo
           sapiens]
          Length = 123

 Score = 37.4 bits (85), Expect = 0.065
 Identities = 27/85 (31%), Positives = 41/85 (48%), Gaps = 7/85 (8%)

Query: 437 RKTFEKDSKAEEVWMKFRKEDSSKRIRKSHKRPKDPQNK----ERASTKERTLKKKKRKL 492
           +K  E+  + EE   +  KE   K  RK  ++ K+ + K    E+   KE   KK+KRK 
Sbjct: 7   KKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRK- 65

Query: 493 TLTQMVGKPEELEEEGDVEEGYRRE 517
              +   + EE EEE + EE  + E
Sbjct: 66  --RKKKKEEEEREEEEEEEEEEKEE 88



 Score = 37.0 bits (84), Expect = 0.084
 Identities = 25/77 (32%), Positives = 43/77 (55%), Gaps = 2/77 (2%)

Query: 441 EKDSKAEEVWMKFRKEDSSKRIRKSHKRPKDPQNKERASTKERTLKKKKRKLTLTQMVGK 500
           EK+ K +E   + RKE   K+  K  ++ K+ + +E+   ++R  KKK+ +    +   +
Sbjct: 24  EKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRK-KKKEEEEREEEEEEE 82

Query: 501 PEELEEEGDVEEGYRRE 517
            EE EEE + EEG RR+
Sbjct: 83  EEEKEEE-EKEEGRRRK 98



 Score = 33.1 bits (74), Expect = 1.2
 Identities = 21/83 (25%), Positives = 41/83 (49%), Gaps = 2/83 (2%)

Query: 437 RKTFEKDSKAEEVWMKFRKEDSSKRIRKSHKRPKDPQNKERASTKERTLKKKKRKLTLTQ 496
           RK  EK  K +E   +  KE+  K+ ++  K+ K+ + +E    +E   K+++ K    +
Sbjct: 37  RKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRR 96

Query: 497 MVGKPEEL--EEEGDVEEGYRRE 517
              K +    EEE + ++  RR+
Sbjct: 97  RKKKKKRRRKEEEEEKKKKRRRK 119



 Score = 30.8 bits (68), Expect = 6.0
 Identities = 18/82 (21%), Positives = 39/82 (47%)

Query: 452 KFRKEDSSKRIRKSHKRPKDPQNKERASTKERTLKKKKRKLTLTQMVGKPEELEEEGDVE 511
           K +K+  ++   ++ +  ++ + + +   K +  +K+K K   T+   K +E EEE    
Sbjct: 3   KKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKR 62

Query: 512 EGYRREISSSPESCPEEIKHEE 533
           +  R++     E   EE + EE
Sbjct: 63  KRKRKKKKEEEEREEEEEEEEE 84


>gi|84043963 eukaryotic translation initiation factor 5B [Homo
           sapiens]
          Length = 1220

 Score = 37.4 bits (85), Expect = 0.065
 Identities = 44/213 (20%), Positives = 92/213 (43%), Gaps = 40/213 (18%)

Query: 349 AKMSKKEKISEKMEIKEGEETKKELVLESNPKWEALTEVLKEIEAENKESEALGGPGQVL 408
           A   K E  +   +  EG++ KK+             +  K+ E E KE E   GP +  
Sbjct: 294 ASEEKAETPTAAEDDNEGDKKKKD-------------KKKKKGEKEEKEKEKKKGPSKAT 340

Query: 409 ICASDDRTCSQLRDYITLGAEAFLLRLYRKTFEKDSKAEEVWMKFRKEDSSKRIRKSHKR 468
           + A  +   ++L++           R  R+  E+  + EE+  K ++E+  ++ ++  K+
Sbjct: 341 VKAMQE-ALAKLKEEEE--------RQKREEEERIKRLEELEAKRKEEERLEQEKRERKK 391

Query: 469 PKDPQNKERASTKERTLKKKKR----------KLTLTQMVGKP--EELEEEGDVEEGYRR 516
            K+ + KER   + + L K +R          KL   Q V  P  + L ++  + E  +R
Sbjct: 392 QKEKERKERLKKEGKLLTKSQREARARAEATLKLLQAQGVEVPSKDSLPKKRPIYEDKKR 451

Query: 517 EISSSPESCPEEIKHEEFDVNLSSDAAFGILKE 549
                 +  P++++ +E   ++   AA  ++++
Sbjct: 452 ------KKIPQQLESKEVSESMELCAAVEVMEQ 478


>gi|50348611 mitochondrial tumor suppressor 1 isoform 1 [Homo sapiens]
          Length = 1270

 Score = 37.0 bits (84), Expect = 0.084
 Identities = 52/260 (20%), Positives = 115/260 (44%), Gaps = 43/260 (16%)

Query: 308  NLLESLRATEKAFGQNSGWLFLDSSTSMFINARARVYHLPDAKMSKKEKISEKMEIKEGE 367
            NL  +L A EK+  +N          S+ I  +     LP  K  +  +   K E + G 
Sbjct: 867  NLFTALNAVEKSRQKNP--------RSLCIQPQTAPDALPPEKTLELTQYKTKCENQSGF 918

Query: 368  ETK-KELVLESNPKWEALTEVLKEIEAENKES---------EALGGPGQVLICASDDRTC 417
              + K+L+   N K+EALT V++ + +E +E+         E +   G+++  ++     
Sbjct: 919  ILQLKQLLACGNTKFEALTVVIQHLLSEREEALKQHKTLSQELVNLRGELVTASTTCEKL 978

Query: 418  SQLRDYITLGAEAFLLRLYRKTFEKDSKAEEVWMKFRKEDSSKRIRKSHKRPKDPQNK-- 475
             + R+ +    EAF+ +   +  E++++ +E + +  ++     I ++ K     Q +  
Sbjct: 979  EKARNELQTVYEAFVQQHQAEKTERENRLKEFYTREYEKLRDTYIEEAEKYKMQLQEQFD 1038

Query: 476  -------------ERASTKERTLKKKKRKLTLTQMVGKPEELEEE------GDVEEGYRR 516
                         E + +++  L KK  + +L++ + K  E+E++       + +E   +
Sbjct: 1039 NLNAAHETSKLEIEASHSEKLELLKKAYEASLSE-IKKGHEIEKKSLEDLLSEKQESLEK 1097

Query: 517  EIS---SSPESCPEEIKHEE 533
            +I+   S  ++  E++K EE
Sbjct: 1098 QINDLKSENDALNEKLKSEE 1117


>gi|50348617 mitochondrial tumor suppressor 1 isoform 2 [Homo sapiens]
          Length = 1216

 Score = 37.0 bits (84), Expect = 0.084
 Identities = 52/260 (20%), Positives = 115/260 (44%), Gaps = 43/260 (16%)

Query: 308  NLLESLRATEKAFGQNSGWLFLDSSTSMFINARARVYHLPDAKMSKKEKISEKMEIKEGE 367
            NL  +L A EK+  +N          S+ I  +     LP  K  +  +   K E + G 
Sbjct: 813  NLFTALNAVEKSRQKNP--------RSLCIQPQTAPDALPPEKTLELTQYKTKCENQSGF 864

Query: 368  ETK-KELVLESNPKWEALTEVLKEIEAENKES---------EALGGPGQVLICASDDRTC 417
              + K+L+   N K+EALT V++ + +E +E+         E +   G+++  ++     
Sbjct: 865  ILQLKQLLACGNTKFEALTVVIQHLLSEREEALKQHKTLSQELVNLRGELVTASTTCEKL 924

Query: 418  SQLRDYITLGAEAFLLRLYRKTFEKDSKAEEVWMKFRKEDSSKRIRKSHKRPKDPQNK-- 475
             + R+ +    EAF+ +   +  E++++ +E + +  ++     I ++ K     Q +  
Sbjct: 925  EKARNELQTVYEAFVQQHQAEKTERENRLKEFYTREYEKLRDTYIEEAEKYKMQLQEQFD 984

Query: 476  -------------ERASTKERTLKKKKRKLTLTQMVGKPEELEEE------GDVEEGYRR 516
                         E + +++  L KK  + +L++ + K  E+E++       + +E   +
Sbjct: 985  NLNAAHETSKLEIEASHSEKLELLKKAYEASLSE-IKKGHEIEKKSLEDLLSEKQESLEK 1043

Query: 517  EIS---SSPESCPEEIKHEE 533
            +I+   S  ++  E++K EE
Sbjct: 1044 QINDLKSENDALNEKLKSEE 1063


>gi|50348626 mitochondrial tumor suppressor 1 isoform 4 [Homo
           sapiens]
          Length = 517

 Score = 37.0 bits (84), Expect = 0.084
 Identities = 52/260 (20%), Positives = 115/260 (44%), Gaps = 43/260 (16%)

Query: 308 NLLESLRATEKAFGQNSGWLFLDSSTSMFINARARVYHLPDAKMSKKEKISEKMEIKEGE 367
           NL  +L A EK+  +N          S+ I  +     LP  K  +  +   K E + G 
Sbjct: 114 NLFTALNAVEKSRQKNP--------RSLCIQPQTAPDALPPEKTLELTQYKTKCENQSGF 165

Query: 368 ETK-KELVLESNPKWEALTEVLKEIEAENKES---------EALGGPGQVLICASDDRTC 417
             + K+L+   N K+EALT V++ + +E +E+         E +   G+++  ++     
Sbjct: 166 ILQLKQLLACGNTKFEALTVVIQHLLSEREEALKQHKTLSQELVNLRGELVTASTTCEKL 225

Query: 418 SQLRDYITLGAEAFLLRLYRKTFEKDSKAEEVWMKFRKEDSSKRIRKSHKRPKDPQNK-- 475
            + R+ +    EAF+ +   +  E++++ +E + +  ++     I ++ K     Q +  
Sbjct: 226 EKARNELQTVYEAFVQQHQAEKTERENRLKEFYTREYEKLRDTYIEEAEKYKMQLQEQFD 285

Query: 476 -------------ERASTKERTLKKKKRKLTLTQMVGKPEELEEE------GDVEEGYRR 516
                        E + +++  L KK  + +L++ + K  E+E++       + +E   +
Sbjct: 286 NLNAAHETSKLEIEASHSEKLELLKKAYEASLSE-IKKGHEIEKKSLEDLLSEKQESLEK 344

Query: 517 EIS---SSPESCPEEIKHEE 533
           +I+   S  ++  E++K EE
Sbjct: 345 QINDLKSENDALNEKLKSEE 364


>gi|239050813 lipoxygenase homology domains 1 isoform 1 [Homo
           sapiens]
          Length = 2211

 Score = 37.0 bits (84), Expect = 0.084
 Identities = 26/75 (34%), Positives = 38/75 (50%), Gaps = 3/75 (4%)

Query: 462 IRKSHKRPKDPQNKERASTKERTLKKKKR---KLTLTQMVGKPEELEEEGDVEEGYRREI 518
           +R+    P++   K++   K R L KK+R   KL   +   K  + E+EG+ EE    E 
Sbjct: 903 VREVDLTPEEEARKKKEKDKLRQLLKKERLKAKLQRKKKKRKGSDEEDEGEEEESSSSEE 962

Query: 519 SSSPESCPEEIKHEE 533
           SSS E   EE + EE
Sbjct: 963 SSSEEEEMEEEEEEE 977


>gi|115648142 centrosomal protein 164kDa [Homo sapiens]
          Length = 1460

 Score = 37.0 bits (84), Expect = 0.084
 Identities = 51/208 (24%), Positives = 93/208 (44%), Gaps = 32/208 (15%)

Query: 345 HLPDAKMSKKEKISEKMEIKEGEET-----KKELVLESNPKWEALTEVLKEIEAENKESE 399
           HL ++K  K +++ EK+  +E EE      +KE  L S    E L + ++E EA  +E E
Sbjct: 609 HLLESKQEKMQQLREKLCQEEEEEILRLHQQKEQSLSSLR--ERLQKAIEEEEARMREEE 666

Query: 400 ALGGPGQVL--ICASDDRTCSQLRDYITLGAEAFLLRLYRKTFEKDSKAEEVWMKFRKED 457
           +     Q L  + A    +     D I    EA L +L R+  E   KAE   ++ +   
Sbjct: 667 S-----QRLSWLRAQVQSSTQADEDQIRAEQEASLQKL-REELESQQKAERASLEQKNRQ 720

Query: 458 SSKRIRKSHKRPKDPQNKERASTKERTLKKKKRKLTLTQMVGKPEE----LEEEGDVE-- 511
             +++++  +  +  +     + KE+ L++ +      Q+ G+ +E    LE+E   E  
Sbjct: 721 MLEQLKEEIEASEKSEQAALNAAKEKALQQLRE-----QLEGERKEAVATLEKEHSAELE 775

Query: 512 ------EGYRREISSSPESCPEEIKHEE 533
                 E   RE+ SS +   +E + +E
Sbjct: 776 RLCSSLEAKHREVVSSLQKKIQEAQQKE 803


>gi|155030242 WD repeat domain 60 [Homo sapiens]
          Length = 1066

 Score = 37.0 bits (84), Expect = 0.084
 Identities = 47/175 (26%), Positives = 78/175 (44%), Gaps = 12/175 (6%)

Query: 348 DAKMSKKEKISEK-MEIKEGEETKKELVLESNPKWEALTEVLKEIEAENKESEALGGPGQ 406
           DAK  +KEK+ EK  E ++     K+   E + +  A  E L++  A +          Q
Sbjct: 95  DAKDREKEKLKEKHREAEKSHSRGKDREKEKDRR--ARKEELRQTVAHHNLLGQETRDRQ 152

Query: 407 VLICA-----SDDRTCSQLRDYITLGAEAFLLRLYR--KTFEKDSKAEEVWMKFRKEDSS 459
           +L  A     S  +  S+ +D  +   +    R YR  K    DSK   +     KE+  
Sbjct: 153 LLERAERKGRSVSKVRSEEKDEDSERGDEDRERRYRERKLQYGDSKDNPLKYWLYKEEGE 212

Query: 460 KRIRKSHKRPKDPQNKERASTKERTLKKKKRKLTLTQMVGKPEELEEEGDVEEGY 514
           +R RK  +  +D +++E++ST+E+  K  K K        K EE  +E   +EG+
Sbjct: 213 RRHRKPREPDRDNKHREKSSTREKREKYSKEK--SNSFSDKGEERHKEKRHKEGF 265


>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
          Length = 2230

 Score = 37.0 bits (84), Expect = 0.084
 Identities = 73/378 (19%), Positives = 150/378 (39%), Gaps = 35/378 (9%)

Query: 194 PRFHVAVNSFLEQHKPE-----VVEIHVSMTPTMLAIQTAIL---DILNACLKELKCHNP 245
           P+       F ++  PE     VVE   S+  T+  +Q  +    ++L  C + ++ H  
Sbjct: 249 PQLEPQAEVFTKEENPESDGEPVVEDGTSVK-TLETLQQRVKRQENLLKRCKETIQSHKE 307

Query: 246 SLEVEDLSLENAIGKPFDKTIRHYLDPLWHQLGAKTKSLVQDLKILRTLLQYLSQYDCVT 305
              +   S + A+ +  D+ ++         +  KTK L+  L+  + L++ L Q   + 
Sbjct: 308 QCTLLT-SEKEALQEQLDERLQELEKIKDLHMAEKTK-LITQLRDAKNLIEQLEQDKGMV 365

Query: 306 FLNLLESLRATEKAFGQNSGWLFLDSSTSMFINARARVYHLPDAKMSKKEKISEKMEIKE 365
                  +  T            L+         R+R+  +       +E+  EK E   
Sbjct: 366 IAETKRQMHET------------LEMKEEEIAQLRSRIKQMTTQGEELREQ-KEKSERAA 412

Query: 366 GEETKKELVLESNPKWEALTEVLKEIEAENKESEALGGPGQVLICASDDRTCSQLRDYIT 425
            EE +K L      + EA  ++  E++ + K  E      ++ +     R   ++ D + 
Sbjct: 413 FEELEKALSTAQKTE-EARRKLKAEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDVMK 471

Query: 426 LGAEAFLLRLYRKTFEKD--SKAEEVWMKFR------KEDSSKRIRKSHKRP-KDPQNKE 476
             +E  + +L +K  EK+   K +E+  K +      +E     + KS     K  Q KE
Sbjct: 472 KSSEEQIAKL-QKLHEKELARKEQELTKKLQTREREFQEQMKVALEKSQSEYLKISQEKE 530

Query: 477 RASTKERTLKKKKRKLTLTQMVGKPEELEEEGDVEEGYRREISSSPESCPEEIKHEEFDV 536
           +  +      + ++K  LT+   K  +L++E +       E+ SS E   +E K++  D+
Sbjct: 531 QQESLALEELELQKKAILTESENKLRDLQQEAETYRTRILELESSLEKSLQENKNQSKDL 590

Query: 537 NLSSDAAFGILKEPLTII 554
            +  +A      + +T++
Sbjct: 591 AVHLEAEKNKHNKEITVM 608


>gi|81295816 nasopharyngeal epithelium specific protein 1 [Homo
           sapiens]
          Length = 551

 Score = 37.0 bits (84), Expect = 0.084
 Identities = 40/182 (21%), Positives = 86/182 (47%), Gaps = 27/182 (14%)

Query: 353 KKEKISEKMEIKEGEETKKELVLESNPKWEALTEVLKE-----IEAENK----ESEALGG 403
           +KE   + +  ++    +KE+V  +N K   L EV KE     ++  NK    + E L  
Sbjct: 134 EKEATMDAVMTRKKIMKQKEMVWNNNKKLSDLEEVAKERAQNLLQRANKLRMEQEEELKD 193

Query: 404 PGQVLICASDDRTCSQLRDYITLGAEAFLLRLYRKTFEKDSKAEEVWMKFRKEDSSKRIR 463
             ++++ A     C  +RD     A+    +  +K  + + K  +  M+  ++ S +R  
Sbjct: 194 MSKIILNAK----CHAIRD-----AQILEKQQIQKELDTEEKRLDQMMEVERQKSIQRQE 244

Query: 464 KSHKRPKDPQNKER--------ASTKERTLKKKKRKLTLTQMVGKPEELEEEGDVEEGYR 515
           +  ++ ++ + + R         + +ER+L  ++R+    QM+   E+L+EE D+++  R
Sbjct: 245 ELERKRREERIRGRRQIVEQMEKNQEERSLLAEQREQEKEQMLEYMEQLQEE-DLKDMER 303

Query: 516 RE 517
           R+
Sbjct: 304 RQ 305


>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
           [Homo sapiens]
          Length = 899

 Score = 36.6 bits (83), Expect = 0.11
 Identities = 39/196 (19%), Positives = 83/196 (42%), Gaps = 35/196 (17%)

Query: 353 KKEKISEKMEIKEGEET----------KKELVLESNPKWEALTEVLKEIEAENKESEALG 402
           +++++ E+ E++E EE           ++E + E   K     E L E E + +E E   
Sbjct: 333 QEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKM 392

Query: 403 GPGQVLICASDDRTCSQLRDYITLGAEAFLLRLYRKTFEKDSKAEEVWMKFRKEDSSKRI 462
              +  +   D+R                     R+  E+  + E++W +  K    K++
Sbjct: 393 RDQEERMWEQDERL--------------------REKEERMREQEKMWEQVEKMREEKKM 432

Query: 463 RKSHKRPKDPQNK--ERASTKERTLKKKKRKLTLTQMVGKPEELEE---EGDVEEGYRRE 517
           ++  K+ +D + K  E    +ER  K ++ + T+ +   K ++ EE   E + +E  ++ 
Sbjct: 433 QEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQR 492

Query: 518 ISSSPESCPEEIKHEE 533
           +    E   E+ K +E
Sbjct: 493 LPEQKEKLWEQEKMQE 508



 Score = 35.0 bits (79), Expect = 0.32
 Identities = 36/170 (21%), Positives = 79/170 (46%), Gaps = 9/170 (5%)

Query: 348 DAKMSKKEKISEK-MEIKEGEET---KKELVLESNPKWEALTEVLKEIEAENKESEALGG 403
           + KM ++E++ E+  +++E EE    ++E + E   K +   E + E E + +E E    
Sbjct: 582 EEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMW 641

Query: 404 PGQVLICASDDRTCSQLRDYITLGAEAFLLRLYRKTFEKDSKAEEVWMKFRKEDSSKRIR 463
             +  +   +++   Q R    L  +   L  + K  E++   E+    + +E   K+ +
Sbjct: 642 EQEEKMWEQEEKMWEQQR----LPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQ 697

Query: 464 KSHKRPKDPQN-KERASTKERTLKKKKRKLTLTQMVGKPEELEEEGDVEE 512
           +  K+  D +  +E  S +ER  K ++ +  + +   K +E EE+   +E
Sbjct: 698 EQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQE 747


>gi|192807336 arsenate resistance protein 2 isoform e [Homo sapiens]
          Length = 871

 Score = 36.6 bits (83), Expect = 0.11
 Identities = 30/109 (27%), Positives = 48/109 (44%), Gaps = 3/109 (2%)

Query: 437 RKTFEKDSKAEEVWMKFRKEDSSKRIRKSHKRPKDPQNKERASTKE--RTLKKKKRKLTL 494
           RKT +KD K E+         +  + +KS +   D + K+  S KE  ++ KK+ RK + 
Sbjct: 300 RKTNDKDEKKEDGKQAENDSSNDDKTKKS-EGDGDKEEKKEDSEKEAKKSSKKRNRKHSG 358

Query: 495 TQMVGKPEELEEEGDVEEGYRREISSSPESCPEEIKHEEFDVNLSSDAA 543
                +    E E + E G   E     E+  E+ K +E +     DAA
Sbjct: 359 DDSFDEGSVSESESESESGQAEEEKEEAEALKEKEKPKEEEWEKPKDAA 407


>gi|192807332 arsenate resistance protein 2 isoform c [Homo sapiens]
          Length = 875

 Score = 36.6 bits (83), Expect = 0.11
 Identities = 30/109 (27%), Positives = 48/109 (44%), Gaps = 3/109 (2%)

Query: 437 RKTFEKDSKAEEVWMKFRKEDSSKRIRKSHKRPKDPQNKERASTKE--RTLKKKKRKLTL 494
           RKT +KD K E+         +  + +KS +   D + K+  S KE  ++ KK+ RK + 
Sbjct: 300 RKTNDKDEKKEDGKQAENDSSNDDKTKKS-EGDGDKEEKKEDSEKEAKKSSKKRNRKHSG 358

Query: 495 TQMVGKPEELEEEGDVEEGYRREISSSPESCPEEIKHEEFDVNLSSDAA 543
                +    E E + E G   E     E+  E+ K +E +     DAA
Sbjct: 359 DDSFDEGSVSESESESESGQAEEEKEEAEALKEKEKPKEEEWEKPKDAA 407


>gi|71061468 centromere protein E [Homo sapiens]
          Length = 2701

 Score = 36.6 bits (83), Expect = 0.11
 Identities = 82/372 (22%), Positives = 147/372 (39%), Gaps = 67/372 (18%)

Query: 204  LEQHKPEVVEIHVSMTPTMLAIQTAILDILNACLKELKCHNPSLE-----VEDLSLE-NA 257
            +EQ K E +E   S   T+   +T I + L   L+E+K      +      E L +E + 
Sbjct: 889  MEQLK-EQLENRDSTLQTVEREKTLITEKLQQTLEEVKTLTQEKDDLKQLQESLQIERDQ 947

Query: 258  IGKPFDKTIRHYLDPLWHQLGAKTKSLVQDLKILRTLLQYLSQYDCVTFLNLLESLRATE 317
            +      T+   +D    QL    +SL Q  + + TL   +S+ +    L++ E+   T+
Sbjct: 948  LKSDIHDTVNMNIDTQ-EQLRNALESLKQHQETINTLKSKISE-EVSRNLHMEENTGETK 1005

Query: 318  KAFGQ--------------NSGWLFLDSSTSMFINARARVYHLPDAKMSKKEK----ISE 359
              F Q              N+  L  D   +  I  + +++ L   K   ++     I+E
Sbjct: 1006 DEFQQKMVGIDKKQDLEAKNTQTLTADVKDNEIIEQQRKIFSLIQEKNELQQMLESVIAE 1065

Query: 360  KMEIKEGEETKKELVLESNPKWEALTEVLK---EIEAENKESEALGGPGQVLICASDDRT 416
            K ++K   +   E+ +E+  +   L + LK   EI A+ K + A+   G++       RT
Sbjct: 1066 KEQLKTDLKENIEMTIENQEELRLLGDELKKQQEIVAQEK-NHAIKKEGEL------SRT 1118

Query: 417  CSQLRDYITLGAEAF---------LLRLYRKTFEKDSKAEEVWMKFRKEDSSKRIRKSH- 466
            C +L +      E           LL +  +  E   K  E+    + E  +K +   H 
Sbjct: 1119 CDRLAEVEEKLKEKSQQLQEKQQQLLNVQEEMSEMQKKINEI-ENLKNELKNKELTLEHM 1177

Query: 467  --------KRPKDPQNKERASTKERTLKKKKRKLTLTQMVGKPEELEEEGDVEEGYRREI 518
                    ++  +   + ++ TKER + K+ +K             E E D   GY REI
Sbjct: 1178 ETERLELAQKLNENYEEVKSITKERKVLKELQK-----------SFETERDHLRGYIREI 1226

Query: 519  SSSPESCPEEIK 530
             ++     EE+K
Sbjct: 1227 EATGLQTKEELK 1238



 Score = 32.7 bits (73), Expect = 1.6
 Identities = 45/195 (23%), Positives = 85/195 (43%), Gaps = 27/195 (13%)

Query: 329  LDSSTSMFINARARVYHLPDAKMSKKEKISEK-----MEIKEGEETKKELVLESNPKWEA 383
            +   T+   N +  + H  DA  ++  KI E+     M +KE +ET  +L    + K + 
Sbjct: 1744 VSEKTNEISNMQKDLEHSNDALKAQDLKIQEELRIAHMHLKEQQETIDKLRGIVSEKTDK 1803

Query: 384  LTEVLKEIEAEN-----KESEALGGPGQVLICASD-----------DRTCSQLRDY-ITL 426
            L+ + K++E  N     K  E      Q++    D           ++   Q++D  +TL
Sbjct: 1804 LSNMQKDLENSNAKLQEKIQELKANEHQLITLKKDVNETQKKVSEMEQLKKQIKDQSLTL 1863

Query: 427  G-AEAFLLRLYRKTFEKDSKAEEVWMKFRKEDSSKRIRKSHKRPKDPQNKERASTKERTL 485
               E   L L +K  E     EE+    ++ D+ +R+ ++ K  +D   +    TK R L
Sbjct: 1864 SKLEIENLNLAQKLHE---NLEEMKSVMKERDNLRRVEETLKLERDQLKESLQETKARDL 1920

Query: 486  KKKKRKLTLTQMVGK 500
             + +++L   +M+ K
Sbjct: 1921 -EIQQELKTARMLSK 1934


>gi|91176325 bromodomain adjacent to zinc finger domain, 2A [Homo
           sapiens]
          Length = 1905

 Score = 36.6 bits (83), Expect = 0.11
 Identities = 25/111 (22%), Positives = 53/111 (47%), Gaps = 9/111 (8%)

Query: 441 EKDSKAEEVWMKFRKEDSSKRIRKSHKRPKDPQNKERASTKERTLKKKKR----KLTLTQ 496
           E+D+     W++   E+   RI+    +   P+N E+A TKE    K+ R    K+ +T+
Sbjct: 624 ERDTPEGLQWVQLSAEEIPSRIQAITGKRGRPRNTEKAKTKEVPKVKRGRGRPPKVKITE 683

Query: 497 MVGKPE-----ELEEEGDVEEGYRREISSSPESCPEEIKHEEFDVNLSSDA 542
           ++ K +     +LE +  + E  + +I+ S +   ++++  E    +   A
Sbjct: 684 LLNKTDNRPLKKLEAQETLNEEDKAKIAKSKKKMRQKVQRGECQTTIQGQA 734



 Score = 30.4 bits (67), Expect = 7.9
 Identities = 32/149 (21%), Positives = 59/149 (39%), Gaps = 12/149 (8%)

Query: 432 LLRLYRKTFEKDSKAEEVWMKFRKEDSSKRIRKSHKRPKDPQNKERASTKERTLKKKKRK 491
           +  L  KT  +  K  E      +ED +K I KS K+ +    +    T  +   + KRK
Sbjct: 681 ITELLNKTDNRPLKKLEAQETLNEEDKAK-IAKSKKKMRQKVQRGECQTTIQGQARNKRK 739

Query: 492 LTLTQMVGKPEELEEEGDVEEGYRREISSSPESCPEEIKHEEFDVNLSSDAAFGILKEPL 551
                +  K  + + + + E+G  ++     E   E++K E+ +     +      KE +
Sbjct: 740 QETKSLKQKEAKKKSKAEKEKGKTKQ-----EKLKEKVKREKKEKVKMKE------KEEV 788

Query: 552 TIIHPLLGCSDPYALTRVLHEVEPRYVVL 580
           T   P        A  R L E + + ++L
Sbjct: 789 TKAKPACKADKTLATQRRLEERQRQQMIL 817


>gi|12711674 UPF3 regulator of nonsense transcripts homolog B
           isoform 2 [Homo sapiens]
          Length = 470

 Score = 36.2 bits (82), Expect = 0.14
 Identities = 51/187 (27%), Positives = 82/187 (43%), Gaps = 27/187 (14%)

Query: 350 KMSKKEKISEKMEIKEGEETKKELVLESNPKWEA-LTEVLKEIEAENKESEALGGPGQVL 408
           K+ K ++I E+ ++K+  + K     E   + E    E  K+++ EN   E   G     
Sbjct: 249 KLKKIDRIPERDKLKDEPKIKLLKKPEKGDEKELDKREKAKKLDKENLSDERASGQS--- 305

Query: 409 ICASDDRTCSQLRDYITLGAEAFLLRLYRKTFEKDSKAEEVWMKFRKEDSSKRIRKSHKR 468
            C    R+ S+L+D      E    R YR   E++ + E      R ++   R R+  KR
Sbjct: 306 -CTLPKRSDSELKDEKPKRPEDESGRDYR---EREREYE------RDQERILRERERLKR 355

Query: 469 PKDPQNKERASTKERTLKKKKRKLTLTQMVGKPEELEEEGDV--EEGYRREISSSPESCP 526
               Q +ER   KER  K+K  K        K EE+++E D   ++G + E + S  S  
Sbjct: 356 ----QEEERRRQKERYEKEKTFK-------RKEEEMKKEKDTLRDKGKKAESTESIGSSE 404

Query: 527 EEIKHEE 533
           +  K EE
Sbjct: 405 KTEKKEE 411


>gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 275

 Score = 35.8 bits (81), Expect = 0.19
 Identities = 22/76 (28%), Positives = 38/76 (50%)

Query: 442 KDSKAEEVWMKFRKEDSSKRIRKSHKRPKDPQNKERASTKERTLKKKKRKLTLTQMVGKP 501
           ++ K ++   +  +E+  +R RK  KR K  + KER   KER  +++KRK    +   K 
Sbjct: 112 RERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKK 171

Query: 502 EELEEEGDVEEGYRRE 517
            E   +   +E  R+E
Sbjct: 172 RERNRKERKKERERKE 187



 Score = 33.5 bits (75), Expect = 0.93
 Identities = 22/64 (34%), Positives = 32/64 (50%), Gaps = 4/64 (6%)

Query: 434 RLYRKTFEKDSKAEEVWMKFRKEDSSKRIRKSHKRPKDPQNKERASTKERTLKKKKRKLT 493
           R  RK  E++ K E    + RKE   +R RK  +  K  + KER   KER   +K  + T
Sbjct: 160 RKKRKKEEREKKRE----RNRKERKKERERKERRERKKERKKERRKKKERKKDRKTDRQT 215

Query: 494 LTQM 497
            +Q+
Sbjct: 216 DSQV 219



 Score = 33.1 bits (74), Expect = 1.2
 Identities = 24/77 (31%), Positives = 37/77 (48%), Gaps = 3/77 (3%)

Query: 441 EKDSKAEEVWMKFRKEDSSKRIRKSHKRPKDPQNKERASTKERTLKKKKRKLTLTQMVGK 500
           +K+ K  E   K R+E   K+ RK  +R +  + KER    +R  K+KKRK    +   +
Sbjct: 117 KKERKERERENKQRRERKRKKRRKKKRRKERKREKERG---KRERKRKKRKKEEREKKRE 173

Query: 501 PEELEEEGDVEEGYRRE 517
               E + + E   RRE
Sbjct: 174 RNRKERKKERERKERRE 190



 Score = 32.7 bits (73), Expect = 1.6
 Identities = 25/96 (26%), Positives = 47/96 (48%), Gaps = 2/96 (2%)

Query: 437 RKTFEKDSKAEEVWMKFRKEDSSKRIRKSHKRPKDPQNKERASTKERTLKKKKRKLTLTQ 496
           R+  +K+ K  E   + R+E   K+ RK  +R ++ Q +ER   K+R  KK++++    +
Sbjct: 94  RRKRKKEKKKRERKQRGRRERKKKKERKERER-ENKQRRER-KRKKRRKKKRRKERKREK 151

Query: 497 MVGKPEELEEEGDVEEGYRREISSSPESCPEEIKHE 532
             GK E   ++   EE  ++   +  E   E  + E
Sbjct: 152 ERGKRERKRKKRKKEEREKKRERNRKERKKERERKE 187



 Score = 32.0 bits (71), Expect = 2.7
 Identities = 29/102 (28%), Positives = 43/102 (42%), Gaps = 13/102 (12%)

Query: 437 RKTFEKDSKAE-EVWMKFRKEDSSKRIRKSH-----KRPKDPQNKERASTKERTLKKKKR 490
           RK  EK  K   E   + RK++  KR RK       K+ K+ + +ER + + R  K+KKR
Sbjct: 79  RKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKR 138

Query: 491 KLTLTQMVGKPEELEEEGDVEEGYRREISSSPESCPEEIKHE 532
           +        K    E + + E G R       +    E K E
Sbjct: 139 R-------KKKRRKERKREKERGKRERKRKKRKKEEREKKRE 173



 Score = 30.8 bits (68), Expect = 6.0
 Identities = 16/55 (29%), Positives = 27/55 (49%)

Query: 437 RKTFEKDSKAEEVWMKFRKEDSSKRIRKSHKRPKDPQNKERASTKERTLKKKKRK 491
           RK  E+  + E    +  K+   +R ++  KR K+ + +ER     R  KKKK +
Sbjct: 66  RKKRERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKER 120


>gi|94681063 bromodomain adjacent to zinc finger domain, 2B [Homo
            sapiens]
          Length = 2168

 Score = 35.8 bits (81), Expect = 0.19
 Identities = 35/153 (22%), Positives = 64/153 (41%), Gaps = 29/153 (18%)

Query: 351  MSKKEKISEKMEIKEGEETKKELVLESNPKWEALTEVLKEIEAENKESEALGGPGQVLIC 410
            M ++EKI    +I+  +E + + +LE+  K +      K +EAE +  E      Q ++ 
Sbjct: 941  MKQQEKIKRIQQIRMEKELRAQQILEAKKKKKEEAANAKLLEAEKRIKEKEMRRQQAVLL 1000

Query: 411  ASDDRTCSQLRDYITLGAEAFLLRLYRKTFEKDSKAEEVWMKFRKEDSSKRIRKSHKRPK 470
               +R   + R ++ L           K  E   KAEE                  +R K
Sbjct: 1001 KHQER--ERRRQHMML----------MKAMEARKKAEE-----------------KERLK 1031

Query: 471  DPQNKERASTKERTLKKKKRKLTLTQMVGKPEE 503
              +  E+   KER L++++ +L + + + KP E
Sbjct: 1032 QEKRDEKRLNKERKLEQRRLELEMAKELKKPNE 1064


>gi|117553580 adaptor-related protein complex 3, delta 1 subunit
           isoform 2 [Homo sapiens]
          Length = 1153

 Score = 35.4 bits (80), Expect = 0.25
 Identities = 27/90 (30%), Positives = 39/90 (43%), Gaps = 5/90 (5%)

Query: 435 LYRKTFEKDSKAEEVWMKFRKEDSSKRIRKSHKRPKDPQNKERASTKERTLKKKKRKLTL 494
           +  K  +K  K E+   +  ++   K+ ++  K PK  + K R   +ERT  KKK K   
Sbjct: 836 MVEKKSKKPKKKEKKHKEKERDKEKKKEKEKKKSPKPKKKKHRKEKEERTKGKKKSK--- 892

Query: 495 TQMVGKPEELEEEGDVEEGYRREISSSPES 524
            Q  G  E   E   V+ G   E    PES
Sbjct: 893 KQPPGSEEAAGE--PVQNGAPEEEQLPPES 920



 Score = 34.3 bits (77), Expect = 0.55
 Identities = 26/123 (21%), Positives = 58/123 (47%), Gaps = 9/123 (7%)

Query: 428 AEAFLLRLYRKTFEKDSKAEEVWMKFRKEDSSKRIRKSHKRPKDPQNKERASTKERTLKK 487
           +E   ++ +R T    S  ++V M  +K    K+  K HK  +  + K++   K+++ K 
Sbjct: 813 SEKLPIQKHRNTETSKSPEKDVPMVEKKSKKPKKKEKKHKEKERDKEKKKEKEKKKSPKP 872

Query: 488 KKRKLTLTQMVGKPEELEEEGDVEEGYRREISSSPESCPEEIKH-EEFDVNLSSDAAFGI 546
           KK+K          +E EE    ++  +++   S E+  E +++    +  L  ++++ +
Sbjct: 873 KKKK--------HRKEKEERTKGKKKSKKQPPGSEEAAGEPVQNGAPEEEQLPPESSYSL 924

Query: 547 LKE 549
           L E
Sbjct: 925 LAE 927


>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
          Length = 1020

 Score = 35.4 bits (80), Expect = 0.25
 Identities = 41/187 (21%), Positives = 75/187 (40%), Gaps = 16/187 (8%)

Query: 348 DAKMSKKEKISEKMEIKEGEETKKELVLESNPKWEALTEVLKEIEAENKESEALGGPGQV 407
           +AK  +KE+     E+K  E+ K            A  E     EA++ E E    P +V
Sbjct: 529 EAKSPEKEEAKSPAEVKSPEKAKS----------PAKEEAKSPPEAKSPEKEEAKSPAEV 578

Query: 408 LICASDDRTCSQLRDYITLGAEAFLLRLYRKTFEKDSKA-EEVWMKFRKEDSSKRIRKSH 466
               S ++  S  ++     AEA      +   ++++K+  E     ++E  S    KS 
Sbjct: 579 ---KSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSP 635

Query: 467 KRPKDPQNKERASTKERTLKKKKRKLTLTQMVGKPEELEEEG-DVEEGYRREISSSPESC 525
           ++ K P  KE A + E+    +K +    +    P + E +  +  +   +  + SPE  
Sbjct: 636 EKAKSP-TKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKA 694

Query: 526 PEEIKHE 532
              +K E
Sbjct: 695 KSPVKEE 701



 Score = 35.4 bits (80), Expect = 0.25
 Identities = 31/102 (30%), Positives = 46/102 (45%), Gaps = 4/102 (3%)

Query: 442 KDSKAEEVWMKFRKEDSSKRIRKSHKRPKDPQNKERASTKERT-LKKKKRKLTLTQMVGK 500
           K+SK E    K   ED  K      + P   + KE A  KE+T + KK+      +   K
Sbjct: 886 KESKVEA--KKEEAEDKKKVPTPEKEAPAKVEVKEDAKPKEKTEVAKKEPDDAKAKEPSK 943

Query: 501 PEELEEEGDVEEGYRREISSSPESCPE-EIKHEEFDVNLSSD 541
           P E +E    ++  + E +  PE  P+ E K +E D  LS +
Sbjct: 944 PAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTLSKE 985



 Score = 32.0 bits (71), Expect = 2.7
 Identities = 46/214 (21%), Positives = 78/214 (36%), Gaps = 38/214 (17%)

Query: 347 PDAKMSKKEKISEKMEIKEGEETKKELVLESNPKWEALT----------EVLKEIEAENK 396
           P+AK  +KE+     E+K  E+ K     E+    EA +          E     EA++ 
Sbjct: 562 PEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPAEAKSP 621

Query: 397 ESEALGGPGQVLICASDDRTCSQLRDYITLGAEAFLLRLYRKTFEKDSKAEEVWMKFRKE 456
             E    P +V    S ++  S  ++      +A           K  + EE     + +
Sbjct: 622 VKEEAKSPAEV---KSPEKAKSPTKEEAKSPEKA-----------KSPEKEEAKSPEKAK 667

Query: 457 DSSKRIRKSHKRPKDP-------QNKERASTKERTLKKKKRKLTLTQMVGKPEE----LE 505
              K   KS ++ K P         K ++  KE     +K K  + +    PE+    ++
Sbjct: 668 SPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKEEAKSPEKAKSPVK 727

Query: 506 EEGDVEEGYR---REISSSPESCPEEIKHEEFDV 536
           EE    E  +   +E + SPE      K +  DV
Sbjct: 728 EEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDV 761



 Score = 32.0 bits (71), Expect = 2.7
 Identities = 46/202 (22%), Positives = 86/202 (42%), Gaps = 28/202 (13%)

Query: 348 DAKMSKKEKISEKMEIKEGEETKKELVLESNPKWEALTEVLKEIEAENKESEALGGPGQV 407
           +AK  +K K   K E K  E+ K       +P+ +A T  +K  EA+    E    P   
Sbjct: 729 EAKTPEKAKSPVKEEAKSPEKAK-------SPE-KAKTLDVKSPEAKTPAKEEARSPADK 780

Query: 408 LICASDDRTCSQLRDYITLGAEAFL-LRLYRKTFEKD-SKAEEVWMKFRKEDSSKRIR-- 463
                 ++  S +++ +    +A   L+   K  EK+  K EEV    ++E+  + ++  
Sbjct: 781 F----PEKAKSPVKEEVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVKEEEKPQEVKVK 836

Query: 464 ------KSHKRPKDPQNKERASTKERTLKKKKRKLTLTQ-----MVGKPEELEEEGDVEE 512
                 +  K P  P+ +E+  +K+    KK+      +      V KP+E + E   EE
Sbjct: 837 EPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEE 896

Query: 513 GYRREISSSPE-SCPEEIKHEE 533
              ++   +PE   P +++ +E
Sbjct: 897 AEDKKKVPTPEKEAPAKVEVKE 918


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.134    0.385 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 33,938,189
Number of Sequences: 37866
Number of extensions: 1532643
Number of successful extensions: 7510
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 39
Number of HSP's successfully gapped in prelim test: 171
Number of HSP's that attempted gapping in prelim test: 6628
Number of HSP's gapped (non-prelim): 856
length of query: 916
length of database: 18,247,518
effective HSP length: 111
effective length of query: 805
effective length of database: 14,044,392
effective search space: 11305735560
effective search space used: 11305735560
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.