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Search of human proteins with 4885075
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4885075 atonal homolog 1 [Homo sapiens]
(354 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4885075 atonal homolog 1 [Homo sapiens] 721 0.0
gi|21553337 atonal homolog 7 [Homo sapiens] 82 6e-16
gi|31077092 neurogenin 2 [Homo sapiens] 79 8e-15
gi|27475985 neurogenic differentiation 6 [Homo sapiens] 77 3e-14
gi|153792190 neurogenic differentiation 4 [Homo sapiens] 76 4e-14
gi|121114306 neurogenic differentiation 1 [Homo sapiens] 76 5e-14
gi|38455396 neurogenin 1 [Homo sapiens] 75 9e-14
gi|68989258 neurogenin 3 [Homo sapiens] 74 2e-13
gi|29126247 basic helix-loop-helix family, member a15 [Homo sapi... 74 2e-13
gi|98986461 neurogenic differentiation 2 [Homo sapiens] 71 2e-12
gi|23097242 nephew of atonal 3 [Homo sapiens] 69 8e-12
gi|30039710 pancreas specific transcription factor, 1a [Homo sap... 64 3e-10
gi|22748877 basic helix-loop-helix domain containing, class B, 5... 62 8e-10
gi|148922889 scleraxis homolog B [Homo sapiens] 61 1e-09
gi|186972126 scleraxis homolog A [Homo sapiens] 61 1e-09
gi|4507363 T-cell acute lymphocytic leukemia 1 [Homo sapiens] 60 2e-09
gi|34147558 lymphoblastic leukemia derived sequence 1 [Homo sapi... 60 2e-09
gi|226498192 atonal homolog 8 [Homo sapiens] 59 7e-09
gi|116805332 musculin [Homo sapiens] 58 1e-08
gi|4507741 twist [Homo sapiens] 57 2e-08
gi|17981708 twist homolog 2 [Homo sapiens] 57 2e-08
gi|48255909 basic helix-loop-helix transcription factor 15 [Homo... 57 2e-08
gi|17978475 oligodendrocyte lineage transcription factor 2 [Homo... 56 6e-08
gi|38202237 transcription factor 21 [Homo sapiens] 56 6e-08
gi|38202239 transcription factor 21 [Homo sapiens] 56 6e-08
gi|4885619 T-cell acute lymphocytic leukemia 2 [Homo sapiens] 55 1e-07
gi|4885665 achaete-scute complex homolog-like 2 [Homo sapiens] 55 1e-07
gi|12545384 basic helix-loop-helix transcription factor HAND2 [H... 53 5e-07
gi|57529222 basic helix-loop-helix domain containing, class B, 4... 53 5e-07
gi|239756681 PREDICTED: basic helix-loop-helix family, member a9... 52 6e-07
>gi|4885075 atonal homolog 1 [Homo sapiens]
Length = 354
Score = 721 bits (1862), Expect = 0.0
Identities = 354/354 (100%), Positives = 354/354 (100%)
Query: 1 MSRLLHAEEWAEVKELGDHHRQPQPHHLPQPPPPPQPPATLQAREHPVYPPELSLLDSTD 60
MSRLLHAEEWAEVKELGDHHRQPQPHHLPQPPPPPQPPATLQAREHPVYPPELSLLDSTD
Sbjct: 1 MSRLLHAEEWAEVKELGDHHRQPQPHHLPQPPPPPQPPATLQAREHPVYPPELSLLDSTD 60
Query: 61 PRAWLAPTLQGICTARAAQYLLHSPELGASEAAAPRDEVDGRGELVRRSSGGASSSKSPG 120
PRAWLAPTLQGICTARAAQYLLHSPELGASEAAAPRDEVDGRGELVRRSSGGASSSKSPG
Sbjct: 61 PRAWLAPTLQGICTARAAQYLLHSPELGASEAAAPRDEVDGRGELVRRSSGGASSSKSPG 120
Query: 121 PVKVREQLCKLKGGVVVDELGCSRQRAPSSKQVNGVQKQRRLAANARERRRMHGLNHAFD 180
PVKVREQLCKLKGGVVVDELGCSRQRAPSSKQVNGVQKQRRLAANARERRRMHGLNHAFD
Sbjct: 121 PVKVREQLCKLKGGVVVDELGCSRQRAPSSKQVNGVQKQRRLAANARERRRMHGLNHAFD 180
Query: 181 QLRNVIPSFNNDKKLSKYETLQMAQIYINALSELLQTPSGGEQPPPPPASCKSDHHHLRT 240
QLRNVIPSFNNDKKLSKYETLQMAQIYINALSELLQTPSGGEQPPPPPASCKSDHHHLRT
Sbjct: 181 QLRNVIPSFNNDKKLSKYETLQMAQIYINALSELLQTPSGGEQPPPPPASCKSDHHHLRT 240
Query: 241 AASYEGGAGNATAAGAQQASGGSQRPTPPGSCRTRFSAPASAGGYSVQLDALHFSTFEDS 300
AASYEGGAGNATAAGAQQASGGSQRPTPPGSCRTRFSAPASAGGYSVQLDALHFSTFEDS
Sbjct: 241 AASYEGGAGNATAAGAQQASGGSQRPTPPGSCRTRFSAPASAGGYSVQLDALHFSTFEDS 300
Query: 301 ALTAMMAQKNLSPSLPGSILQPVQEENSKTSPRSHRSDGEFSPHSHYSDSDEAS 354
ALTAMMAQKNLSPSLPGSILQPVQEENSKTSPRSHRSDGEFSPHSHYSDSDEAS
Sbjct: 301 ALTAMMAQKNLSPSLPGSILQPVQEENSKTSPRSHRSDGEFSPHSHYSDSDEAS 354
>gi|21553337 atonal homolog 7 [Homo sapiens]
Length = 152
Score = 82.4 bits (202), Expect = 6e-16
Identities = 41/57 (71%), Positives = 47/57 (82%)
Query: 159 QRRLAANARERRRMHGLNHAFDQLRNVIPSFNNDKKLSKYETLQMAQIYINALSELL 215
+RRLAANARERRRM GLN AFD+LR V+P + DKKLSKYETLQMA YI AL+ +L
Sbjct: 40 RRRLAANARERRRMQGLNTAFDRLRRVVPQWGQDKKLSKYETLQMALSYIMALTRIL 96
>gi|31077092 neurogenin 2 [Homo sapiens]
Length = 272
Score = 78.6 bits (192), Expect = 8e-15
Identities = 77/214 (35%), Positives = 98/214 (45%), Gaps = 27/214 (12%)
Query: 84 SPELGA-----SEAAAPRDEVDGRGELVRRSSGGASSSKSPGPVKVREQLCK---LKGGV 135
SP L A S A +E G RR G + + G V + C+ L G V
Sbjct: 24 SPALAALTPLSSSADEEEEEEPGASGGARRQRGAEAGQGARGGVAAGAEGCRPARLLGLV 83
Query: 136 VVDELGCSRQRAPS-----SKQVNGVQKQRRLAANARERRRMHGLNHAFDQLRNVIPSFN 190
+ SR RA S ++ V ++K RRL AN RER RMH LN A D LR V+P+F
Sbjct: 84 HDCKRRPSRARAVSRGAKTAETVQRIKKTRRLKANNRERNRMHNLNAALDALREVLPTFP 143
Query: 191 NDKKLSKYETLQMAQIYINALSELLQTPS--GGEQPPPPPASCKSDHHHLRTAASYEGGA 248
D KL+K ETL+ A YI AL+E L+ GG P A L + A
Sbjct: 144 EDAKLTKIETLRFAHNYIWALTETLRLADHCGGGGGGLPGA--------LFSEAVLLSPG 195
Query: 249 GNATAAGAQQASGGSQRPTPPGSCRTRFSAPASA 282
G A+ A +SG S P SC T AP+S+
Sbjct: 196 G---ASAALSSSGDSPSPASTWSC-TNSPAPSSS 225
>gi|27475985 neurogenic differentiation 6 [Homo sapiens]
Length = 337
Score = 76.6 bits (187), Expect = 3e-14
Identities = 47/109 (43%), Positives = 66/109 (60%), Gaps = 6/109 (5%)
Query: 112 GASSSKSPGPVKVREQLCKLKGGVVVDELGCSRQRAPSSKQVNGVQ----KQRRLAANAR 167
G S ++PG +E+ + + DE G R+R K+ ++ K RR ANAR
Sbjct: 45 GKSIKRAPGEETEKEE--EEEDREEEDENGLPRRRGLRKKKTTKLRLERVKFRRQEANAR 102
Query: 168 ERRRMHGLNHAFDQLRNVIPSFNNDKKLSKYETLQMAQIYINALSELLQ 216
ER RMHGLN A D LR V+P ++ +KLSK ETL++A+ YI ALSE+L+
Sbjct: 103 ERNRMHGLNDALDNLRKVVPCYSKTQKLSKIETLRLAKNYIWALSEILR 151
>gi|153792190 neurogenic differentiation 4 [Homo sapiens]
Length = 331
Score = 76.3 bits (186), Expect = 4e-14
Identities = 42/84 (50%), Positives = 57/84 (67%), Gaps = 7/84 (8%)
Query: 144 RQRAPSSKQVNGVQ----KQRRLAANARERRRMHGLNHAFDQLRNVIPSFNNDKKLSKYE 199
++R P K++ + + RR+ ANARER RMHGLN A D LR V+P ++ +KLSK E
Sbjct: 68 KRRGPKKKKMTKARLERFRARRVKANARERTRMHGLNDALDNLRRVMPCYSKTQKLSKIE 127
Query: 200 TLQMAQIYINALSELL---QTPSG 220
TL++A+ YI ALSE+L QTP G
Sbjct: 128 TLRLARNYIWALSEVLETGQTPEG 151
>gi|121114306 neurogenic differentiation 1 [Homo sapiens]
Length = 356
Score = 75.9 bits (185), Expect = 5e-14
Identities = 39/78 (50%), Positives = 55/78 (70%), Gaps = 4/78 (5%)
Query: 144 RQRAPSSKQVNGVQ----KQRRLAANARERRRMHGLNHAFDQLRNVIPSFNNDKKLSKYE 199
++R P K++ + K RR+ ANARER RMHGLN A D LR V+P ++ +KLSK E
Sbjct: 82 KRRGPKKKKMTKARLERFKLRRMKANARERNRMHGLNAALDNLRKVVPCYSKTQKLSKIE 141
Query: 200 TLQMAQIYINALSELLQT 217
TL++A+ YI ALSE+L++
Sbjct: 142 TLRLAKNYIWALSEILRS 159
>gi|38455396 neurogenin 1 [Homo sapiens]
Length = 237
Score = 75.1 bits (183), Expect = 9e-14
Identities = 56/145 (38%), Positives = 74/145 (51%), Gaps = 25/145 (17%)
Query: 144 RQRAPSSKQVNGVQKQRRLAANARERRRMHGLNHAFDQLRNVIPSFNNDKKLSKYETLQM 203
R R S ++ +++ RR+ AN RER RMH LN A D LR+V+PSF +D KL+K ETL+
Sbjct: 77 RTRVRSEALLHSLRRSRRVKANDRERNRMHNLNAALDALRSVLPSFPDDTKLTKIETLRF 136
Query: 204 AQIYINALSELLQ-----TPSGGEQ----PP------PPPASCKSDHHHLRTAASYEGGA 248
A YI AL+E L+ P GG + PP P P S SD A S+ GA
Sbjct: 137 AYNYIWALAETLRLADQGLPGGGARERLLPPQCVPCLPGPPSPASD------AESWGSGA 190
Query: 249 GNATAAGAQQASGGSQ----RPTPP 269
A+ + S+ RP P
Sbjct: 191 AAASPLSDPSSPAASEDFTYRPGDP 215
>gi|68989258 neurogenin 3 [Homo sapiens]
Length = 214
Score = 74.3 bits (181), Expect = 2e-13
Identities = 63/196 (32%), Positives = 84/196 (42%), Gaps = 28/196 (14%)
Query: 93 AAPRDEVDGRGELVRRSSGGASSSKSPGPVKVREQLCKLKGGVVVDELGCSRQRAPSSKQ 152
+AP RG GG + P K+R + +GG R R S
Sbjct: 34 SAPPSPTRTRGNCAEAEEGGCRGA----PRKLRAR----RGG---------RSRPKSELA 76
Query: 153 VNGVQKQRRLAANARERRRMHGLNHAFDQLRNVIPSFNNDKKLSKYETLQMAQIYINALS 212
++ ++ RR AN RER RMH LN A D LR V+P+F +D KL+K ETL+ A YI AL+
Sbjct: 77 LSKQRRSRRKKANDRERNRMHNLNSALDALRGVLPTFPDDAKLTKIETLRFAHNYIWALT 136
Query: 213 ELLQTPSGGEQPPPPPASCKSDHHHLRTAASYEGGAGNATAAGAQQASGGSQRPTP---- 268
+ L+ PPA H S G G+ + + + GS P
Sbjct: 137 QTLRIADHSLYALEPPAP------HCGELGSPGGSPGDWGSLYSPVSQAGSLSPAASLEE 190
Query: 269 -PGSCRTRFSAPASAG 283
PG FSA S G
Sbjct: 191 RPGLLGATFSACLSPG 206
>gi|29126247 basic helix-loop-helix family, member a15 [Homo
sapiens]
Length = 189
Score = 74.3 bits (181), Expect = 2e-13
Identities = 51/124 (41%), Positives = 63/124 (50%), Gaps = 12/124 (9%)
Query: 141 GCSRQRAPSSKQVNGVQK---QRRLAANARERRRMHGLNHAFDQLRNVIPSFNNDKKLSK 197
G R+R P G + QRRL +N RER+RMH LN+AF LR VIP DKKLSK
Sbjct: 54 GEGRRRRPGPSGPGGRRDSSIQRRLESNERERQRMHKLNNAFQALREVIPHVRADKKLSK 113
Query: 198 YETLQMAQIYINALSELLQTPSGGEQP----PPPPASCKSDHHHLRTAASYEGGAGNATA 253
ETL +A+ YI +L+ + T S P P P + H + GGA AT
Sbjct: 114 IETLTLAKNYIKSLTATILTMSSSRLPGLEGPGPKL-----YQHYQQQQQVAGGALGATE 168
Query: 254 AGAQ 257
A Q
Sbjct: 169 AQPQ 172
>gi|98986461 neurogenic differentiation 2 [Homo sapiens]
Length = 382
Score = 70.9 bits (172), Expect = 2e-12
Identities = 39/85 (45%), Positives = 57/85 (67%), Gaps = 7/85 (8%)
Query: 144 RQRAPSSKQVNGVQ----KQRRLAANARERRRMHGLNHAFDQLRNVIPSFNNDKKLSKYE 199
++R P +++ + K RR ANARER RMH LN A D LR V+P ++ +KLSK E
Sbjct: 102 KKRGPKKRKMTKARLERSKLRRQKANARERNRMHDLNAALDNLRKVVPCYSKTQKLSKIE 161
Query: 200 TLQMAQIYINALSELLQTPSGGEQP 224
TL++A+ YI ALSE+L++ G++P
Sbjct: 162 TLRLAKNYIWALSEILRS---GKRP 183
>gi|23097242 nephew of atonal 3 [Homo sapiens]
Length = 166
Score = 68.6 bits (166), Expect = 8e-12
Identities = 36/77 (46%), Positives = 53/77 (68%), Gaps = 2/77 (2%)
Query: 141 GCSRQRAPSSKQVNGVQKQRRLAANARERRRMHGLNHAFDQLRNVIPSFNNDKKLSKYET 200
G S P K+V + +R AAN RER+RM LN AFDQLR +P+F +K+LS+ ET
Sbjct: 85 GVSLLGRPKRKRV--ITYAQRQAANIRERKRMFNLNEAFDQLRRKVPTFAYEKRLSRIET 142
Query: 201 LQMAQIYINALSELLQT 217
L++A +YI+ ++ELL++
Sbjct: 143 LRLAIVYISFMTELLES 159
>gi|30039710 pancreas specific transcription factor, 1a [Homo
sapiens]
Length = 328
Score = 63.5 bits (153), Expect = 3e-10
Identities = 33/59 (55%), Positives = 44/59 (74%)
Query: 158 KQRRLAANARERRRMHGLNHAFDQLRNVIPSFNNDKKLSKYETLQMAQIYINALSELLQ 216
+Q R AAN RERRRM +N AF+ LR+ IP+ +K+LSK +TL++A YIN LSEL+Q
Sbjct: 162 QQLRQAANVRERRRMQSINDAFEGLRSHIPTLPYEKRLSKVDTLRLAIGYINFLSELVQ 220
>gi|22748877 basic helix-loop-helix domain containing, class B, 5
[Homo sapiens]
Length = 381
Score = 62.0 bits (149), Expect = 8e-10
Identities = 60/165 (36%), Positives = 74/165 (44%), Gaps = 27/165 (16%)
Query: 111 GGASSSKSPGPVKVREQLCKLKGGVVVDELGCSRQRAPSSKQVNGVQKQRRLAANARERR 170
GG SSS S G GG G S + SS + + QK RL NARERR
Sbjct: 205 GGGSSSGSSGG-----------GGGSGSGSGGSSSSSSSSSKKSKEQKALRLNINARERR 253
Query: 171 RMHGLNHAFDQLRNVIPSFNND--KKLSKYETLQMAQIYI----NALSELL--------- 215
RMH LN A D+LR VIP ++ +KLSK TL +A+ YI AL E+
Sbjct: 254 RMHDLNDALDELRAVIPYAHSPSVRKLSKIATLLLAKNYILMQAQALEEMRRLVAYLNQG 313
Query: 216 QTPSGGEQPPPPPASCKSDHHHLRTAASYEGGAGNATAAGAQQAS 260
Q S P A+ + H A YE AG +AG A+
Sbjct: 314 QAISAASLPSSAAAAAAAAALHPALGA-YEQAAGYPFSAGLPPAA 357
>gi|148922889 scleraxis homolog B [Homo sapiens]
Length = 201
Score = 61.2 bits (147), Expect = 1e-09
Identities = 45/137 (32%), Positives = 59/137 (43%), Gaps = 21/137 (15%)
Query: 111 GGASSSKSPGPVKVREQLCKLKGGVVVDELGCSRQRAPSSKQVNGVQKQRRLAANARERR 170
G SS P +V C L+G G R G + ++R ANARER
Sbjct: 29 GSDSSGSDEKPCRVHAARCGLQGAR--RRAGGRRAGGGGPGGRPGREPRQRHTANARERD 86
Query: 171 RMHGLNHAFDQLRNVIPSFNNDKKLSKYETLQMAQIYINALSELL--------------- 215
R + +N AF LR +IP+ D+KLSK ETL++A YI+ L +L
Sbjct: 87 RTNSVNTAFTALRTLIPTEPADRKLSKIETLRLASSYISHLGNVLLAGEACGDGQPCHSG 146
Query: 216 ----QTPSGGEQPPPPP 228
G PPPPP
Sbjct: 147 PAFFHAARAGSPPPPPP 163
>gi|186972126 scleraxis homolog A [Homo sapiens]
Length = 201
Score = 61.2 bits (147), Expect = 1e-09
Identities = 45/137 (32%), Positives = 59/137 (43%), Gaps = 21/137 (15%)
Query: 111 GGASSSKSPGPVKVREQLCKLKGGVVVDELGCSRQRAPSSKQVNGVQKQRRLAANARERR 170
G SS P +V C L+G G R G + ++R ANARER
Sbjct: 29 GSDSSGSDEKPCRVHAARCGLQGAR--RRAGGRRAGGGGPGGRPGREPRQRHTANARERD 86
Query: 171 RMHGLNHAFDQLRNVIPSFNNDKKLSKYETLQMAQIYINALSELL--------------- 215
R + +N AF LR +IP+ D+KLSK ETL++A YI+ L +L
Sbjct: 87 RTNSVNTAFTALRTLIPTEPADRKLSKIETLRLASSYISHLGNVLLAGEACGDGQPCHSG 146
Query: 216 ----QTPSGGEQPPPPP 228
G PPPPP
Sbjct: 147 PAFFHAARAGSPPPPPP 163
>gi|4507363 T-cell acute lymphocytic leukemia 1 [Homo sapiens]
Length = 331
Score = 60.5 bits (145), Expect = 2e-09
Identities = 59/217 (27%), Positives = 90/217 (41%), Gaps = 27/217 (12%)
Query: 88 GASEAAAPRD---EVDGRGELVRRSSGGASSSKSPGPV---KVREQLCKLKGG------- 134
G + A AP E+ G G +V+ S ++ +PG + + L L G
Sbjct: 98 GPAPAPAPASVTAELPGDGRMVQLSPPALAAPAAPGRALLYSLSQPLASLGSGFFGEPDA 157
Query: 135 --VVVDELGCSRQRAPSSKQVNG---VQKQRRLAANARERRRMHGLNHAFDQLRNVIPSF 189
+ R+ +P ++ + RR+ N+RER R +N AF +LR +IP+
Sbjct: 158 FPMFTTNNRVKRRPSPYEMEITDGPHTKVVRRIFTNSRERWRQQNVNGAFAELRKLIPTH 217
Query: 190 NNDKKLSKYETLQMAQIYINALSELLQTPSGGEQPPPPPASCKSDHHHLRTAASYEGGAG 249
DKKLSK E L++A YIN L++LL +Q K+ + A GG G
Sbjct: 218 PPDKKLSKNEILRLAMKYINFLAKLL-----NDQEEEGTQRAKTGKDPVVGA----GGGG 268
Query: 250 NATAAGAQQASGGSQRPTPPGSCRTRFSAPASAGGYS 286
GA +P SC + AS Y+
Sbjct: 269 GGGGGGAPPDDLLQDVLSPNSSCGSSLDGAASPDSYT 305
>gi|34147558 lymphoblastic leukemia derived sequence 1 [Homo
sapiens]
Length = 280
Score = 60.5 bits (145), Expect = 2e-09
Identities = 40/117 (34%), Positives = 56/117 (47%), Gaps = 10/117 (8%)
Query: 160 RRLAANARERRRMHGLNHAFDQLRNVIPSFNNDKKLSKYETLQMAQIYINALSELLQTPS 219
RR+ N+RER R +N AF +LR ++P+ D+KLSK E L++A YI L LL+ +
Sbjct: 151 RRVFTNSRERWRQQNVNGAFAELRKLLPTHPPDRKLSKNEVLRLAMKYIGFLVRLLRDQA 210
Query: 220 GG-EQPPPPPASCKSDHHHLRTAASYEGGAGNATAAGAQQ---------ASGGSQRP 266
P PP K H + + G A AA Q + GG+ RP
Sbjct: 211 AALAAGPTPPGPRKRPVHRVPDDGARRGSGRRAEAAARSQPAPPADPDGSPGGAARP 267
>gi|226498192 atonal homolog 8 [Homo sapiens]
Length = 321
Score = 58.9 bits (141), Expect = 7e-09
Identities = 56/193 (29%), Positives = 77/193 (39%), Gaps = 34/193 (17%)
Query: 28 LPQPPPPPQPPATLQAREHPVYPPELSLLDSTDPRAWL-APTLQGICTARAAQYLLHSPE 86
LP PPPPP P QA P P PR L AP + +A A PE
Sbjct: 121 LPTPPPPPPPAPQSQAPGGPEAQPFRE--PGLRPRILLCAPPARPAPSAPPAPPA--PPE 176
Query: 87 LGASEAAAPRDEVDGRGELVR-----RSSGGASSSKSPGPVKVREQLCKLKGGVVVDELG 141
A R + AS K PG
Sbjct: 177 STVRPAPPTRPGESSYSSISHVIYNNHQDSSASPRKRPG--------------------- 215
Query: 142 CSRQRAPSSKQVNGVQKQRRLAANARERRRMHGLNHAFDQLRNVIPSFNNDKKLSKYETL 201
+ +S ++ +Q+ RRL ANARER R+H ++ AF+ LR +P ++ +KLSK L
Sbjct: 216 ---EATAASSEIKALQQTRRLLANARERTRVHTISAAFEALRKQVPCYSYGQKLSKLAIL 272
Query: 202 QMAQIYINALSEL 214
++A YI +L+ L
Sbjct: 273 RIACNYILSLARL 285
>gi|116805332 musculin [Homo sapiens]
Length = 206
Score = 57.8 bits (138), Expect = 1e-08
Identities = 44/127 (34%), Positives = 62/127 (48%), Gaps = 17/127 (13%)
Query: 97 DEVDGRGELVRRSSGGASSSKSPGPVKVREQLCKLK-------GGVVVDELGCSRQRAPS 149
+E D GE R + G A S++ CK K GG G ++ P+
Sbjct: 48 EEEDPDGEEERCALGTAGSAEG----------CKRKRPRVAGGGGAGGSAGGGGKKPLPA 97
Query: 150 SKQVNGVQKQRRLAANARERRRMHGLNHAFDQLRNVIPSFNNDKKLSKYETLQMAQIYIN 209
++ +R AANARER RM L+ AF +L+ +P D KLSK +TL++A YI
Sbjct: 98 KGSAAECKQSQRNAANARERARMRVLSKAFSRLKTSLPWVPPDTKLSKLDTLRLASSYIA 157
Query: 210 ALSELLQ 216
L +LLQ
Sbjct: 158 HLRQLLQ 164
>gi|4507741 twist [Homo sapiens]
Length = 202
Score = 57.4 bits (137), Expect = 2e-08
Identities = 42/117 (35%), Positives = 58/117 (49%), Gaps = 2/117 (1%)
Query: 101 GRGELVRRSSGGASSSKSPGPVKVREQLCKLKGGVVVDELGCSRQRAPSSKQVNGVQKQR 160
G G GG SP K ++ GG G S S + +Q QR
Sbjct: 51 GPGGAAGGGVGGGDEPGSPAQGKRGKKSAGCGGGGGAGGGGGSSSGGGSPQSYEELQTQR 110
Query: 161 RLAANARERRRMHGLNHAFDQLRNVIPSFNNDKKLSKYETLQMAQIYINALSELLQT 217
+ AN RER+R LN AF LR +IP+ +D KLSK +TL++A YI+ L ++LQ+
Sbjct: 111 -VMANVRERQRTQSLNEAFAALRKIIPTLPSD-KLSKIQTLKLAARYIDFLYQVLQS 165
>gi|17981708 twist homolog 2 [Homo sapiens]
Length = 160
Score = 57.4 bits (137), Expect = 2e-08
Identities = 33/74 (44%), Positives = 50/74 (67%), Gaps = 2/74 (2%)
Query: 144 RQRAPSSKQVNGVQKQRRLAANARERRRMHGLNHAFDQLRNVIPSFNNDKKLSKYETLQM 203
++ +PS++ +Q QR LA N RER+R LN AF LR +IP+ +D KLSK +TL++
Sbjct: 52 KKGSPSAQSFEELQSQRILA-NVRERQRTQSLNEAFAALRKIIPTLPSD-KLSKIQTLKL 109
Query: 204 AQIYINALSELLQT 217
A YI+ L ++LQ+
Sbjct: 110 AARYIDFLYQVLQS 123
>gi|48255909 basic helix-loop-helix transcription factor 15 [Homo
sapiens]
Length = 199
Score = 57.4 bits (137), Expect = 2e-08
Identities = 45/132 (34%), Positives = 59/132 (44%), Gaps = 21/132 (15%)
Query: 159 QRRLAANARERRRMHGLNHAFDQLRNVIPSFNNDKKLSKYETLQMAQIYINALSELLQTP 218
++R AANARER R +N AF LR +IP+ D+KLSK ETL++A YI L+ +L
Sbjct: 72 RQRQAANARERDRTQSVNTAFTALRTLIPTEPVDRKLSKIETLRLASSYIAHLANVLLLG 131
Query: 219 SGGEQPPPPPASCKSDHHHLRTAASYEGGAGNATAAGAQ-----------QASGGSQRPT 267
+ P C R A S +G A G Q Q GG +R
Sbjct: 132 DSADDGQP----C------FRAAGSAKGAVPAAADGGRQPRSICTFCLSNQRKGGGRRDL 181
Query: 268 PPGSCRTRFSAP 279
+ R AP
Sbjct: 182 GGSCLKVRGVAP 193
>gi|17978475 oligodendrocyte lineage transcription factor 2 [Homo
sapiens]
Length = 323
Score = 55.8 bits (133), Expect = 6e-08
Identities = 64/214 (29%), Positives = 86/214 (40%), Gaps = 41/214 (19%)
Query: 85 PELGA-------SEAAAPRDEVDGRGELVRRSSGGASSSKSPGPVKVREQLCKLKGGVVV 137
PEL A S A P D++ G G + SS SSS S
Sbjct: 49 PELSAELRGAMGSAGAHPGDKLGGSG--FKSSSSSTSSSTSSA----------------- 89
Query: 138 DELGCSRQRAPSSKQVNGVQKQRRLAANARERRRMHGLNHAFDQLRNVIPSFNND--KKL 195
S + + +Q RL N+RER+RMH LN A D LR V+P + +KL
Sbjct: 90 ---AASSTKKDKKQMTEPELQQLRLKINSRERKRMHDLNIAMDGLREVMPYAHGPSVRKL 146
Query: 196 SKYETLQMAQIYI----NALSELLQTPS---GGEQPPPPPASCKSDHHHLRTAASYEGGA 248
SK TL +A+ YI N+L E+ + S GG P++C H A+ A
Sbjct: 147 SKIATLLLARNYILMLTNSLEEMKRLVSEIYGGHHAGFHPSACGGLAHSAPLPAA---TA 203
Query: 249 GNATAAGAQQASGGSQRPTPPGSCRTRFSAPASA 282
A AA A PP + +A A+A
Sbjct: 204 HPAAAAHAAHHPAVHHPILPPAAAAAAAAAAAAA 237
>gi|38202237 transcription factor 21 [Homo sapiens]
Length = 179
Score = 55.8 bits (133), Expect = 6e-08
Identities = 33/77 (42%), Positives = 50/77 (64%), Gaps = 5/77 (6%)
Query: 144 RQRAPSSKQ-VNGVQKQ----RRLAANARERRRMHGLNHAFDQLRNVIPSFNNDKKLSKY 198
R++AP+ K ++GV ++ +R AANARER RM L+ AF +L+ +P D KLSK
Sbjct: 59 RRKAPTKKSPLSGVSQEGKQVQRNAANARERARMRVLSKAFSRLKTTLPWVPPDTKLSKL 118
Query: 199 ETLQMAQIYINALSELL 215
+TL++A YI L ++L
Sbjct: 119 DTLRLASSYIAHLRQIL 135
>gi|38202239 transcription factor 21 [Homo sapiens]
Length = 179
Score = 55.8 bits (133), Expect = 6e-08
Identities = 33/77 (42%), Positives = 50/77 (64%), Gaps = 5/77 (6%)
Query: 144 RQRAPSSKQ-VNGVQKQ----RRLAANARERRRMHGLNHAFDQLRNVIPSFNNDKKLSKY 198
R++AP+ K ++GV ++ +R AANARER RM L+ AF +L+ +P D KLSK
Sbjct: 59 RRKAPTKKSPLSGVSQEGKQVQRNAANARERARMRVLSKAFSRLKTTLPWVPPDTKLSKL 118
Query: 199 ETLQMAQIYINALSELL 215
+TL++A YI L ++L
Sbjct: 119 DTLRLASSYIAHLRQIL 135
>gi|4885619 T-cell acute lymphocytic leukemia 2 [Homo sapiens]
Length = 108
Score = 54.7 bits (130), Expect = 1e-07
Identities = 28/56 (50%), Positives = 38/56 (67%)
Query: 160 RRLAANARERRRMHGLNHAFDQLRNVIPSFNNDKKLSKYETLQMAQIYINALSELL 215
R++ N RER R +N AF +LR +IP+ DKKLSK ETL++A YIN L ++L
Sbjct: 3 RKIFTNTRERWRQQNVNSAFAKLRKLIPTHPPDKKLSKNETLRLAMRYINFLVKVL 58
>gi|4885665 achaete-scute complex homolog-like 2 [Homo sapiens]
Length = 193
Score = 54.7 bits (130), Expect = 1e-07
Identities = 50/167 (29%), Positives = 69/167 (41%), Gaps = 18/167 (10%)
Query: 140 LGCSRQRAPSSKQVNG--VQKQRRLAANARERRRMHGLNHAFDQLRNVIPSFNNDKKLSK 197
L CSR+R P++ + G RR N RER R+ +N F LR +P KKLSK
Sbjct: 32 LRCSRRRRPATAETGGGAAAVARR---NERERNRVKLVNLGFQALRQHVPHGGASKKLSK 88
Query: 198 YETLQMAQIYINALSELL-------QTPSGGEQPPPPPASCKSDHHHLRTAASYEGGAGN 250
ETL+ A YI AL LL +GG +P S R A +
Sbjct: 89 VETLRSAVEYIRALQRLLAEHDAVRNALAGGLRPQAVRPSAP------RGPPGTTPVAAS 142
Query: 251 ATAAGAQQASGGSQRPTPPGSCRTRFSAPASAGGYSVQLDALHFSTF 297
+ A + GGS P P S + + + + L FS++
Sbjct: 143 PSRASSSPGRGGSSEPGSPRSAYSSDDSGCEGALSPAERELLDFSSW 189
>gi|12545384 basic helix-loop-helix transcription factor HAND2 [Homo
sapiens]
Length = 217
Score = 52.8 bits (125), Expect = 5e-07
Identities = 28/57 (49%), Positives = 37/57 (64%)
Query: 159 QRRLAANARERRRMHGLNHAFDQLRNVIPSFNNDKKLSKYETLQMAQIYINALSELL 215
+RR AN +ERRR +N AF +LR IP+ D KLSK +TL++A YI L +LL
Sbjct: 99 KRRGTANRKERRRTQSINSAFAELRECIPNVPADTKLSKIKTLRLATSYIAYLMDLL 155
>gi|57529222 basic helix-loop-helix domain containing, class B, 4
[Homo sapiens]
Length = 225
Score = 52.8 bits (125), Expect = 5e-07
Identities = 34/71 (47%), Positives = 44/71 (61%), Gaps = 6/71 (8%)
Query: 144 RQRAPSS----KQVNGVQKQRRLAANARERRRMHGLNHAFDQLRNVIPSFNND--KKLSK 197
R+R P S ++ Q+ RL+ NARERRRMH LN A D LR VIP ++ +KLSK
Sbjct: 81 RRRGPGSAADGRRRPREQRSLRLSINARERRRMHDLNDALDGLRAVIPYAHSPSVRKLSK 140
Query: 198 YETLQMAQIYI 208
TL +A+ YI
Sbjct: 141 IATLLLAKNYI 151
>gi|239756681 PREDICTED: basic helix-loop-helix family, member a9
[Homo sapiens]
Length = 203
Score = 52.4 bits (124), Expect = 6e-07
Identities = 43/124 (34%), Positives = 55/124 (44%), Gaps = 8/124 (6%)
Query: 158 KQRRLAANARERRRMHGLNHAFDQLRNVIPSFNNDKKLSKYETLQMAQIYINALSELLQT 217
K RR+AAN RER+R+ N AF+ LR + K+LSK TL+ A I ALS +L+
Sbjct: 64 KARRMAANVRERKRILDYNEAFNALRRALRHDLGGKRLSKIATLRRAIHRIAALSLVLRA 123
Query: 218 PSGGEQPPPPPASCKSDHHHLRTAASYEG--GAGNATAAGAQQASGGSQRPTPPGSCRTR 275
P P C H A G GA AG A + RP+ P + R
Sbjct: 124 ------SPAPRGPCGHLECHGPAARGDTGDTGASPPPPAGPSLARPDAARPSVPSAPRCA 177
Query: 276 FSAP 279
P
Sbjct: 178 SCPP 181
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.127 0.377
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,492,607
Number of Sequences: 37866
Number of extensions: 1067501
Number of successful extensions: 13935
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 301
Number of HSP's successfully gapped in prelim test: 402
Number of HSP's that attempted gapping in prelim test: 9579
Number of HSP's gapped (non-prelim): 3491
length of query: 354
length of database: 18,247,518
effective HSP length: 103
effective length of query: 251
effective length of database: 14,347,320
effective search space: 3601177320
effective search space used: 3601177320
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.