Search of human proteins with 48762700

Search of human proteins with 48762700

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|48762700 GTF2I repeat domain containing 2 [Homo sapiens]
         (949 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|48762700 GTF2I repeat domain containing 2 [Homo sapiens]          1904   0.0  
gi|51241788 GTF2I repeat domain containing 2B [Homo sapiens]         1890   0.0  
gi|14670352 general transcription factor II, i isoform 2 [Homo s...   472   e-133
gi|14670350 general transcription factor II, i isoform 1 [Homo s...   461   e-129
gi|169881252 general transcription factor II, i isoform 4 [Homo ...   453   e-127
gi|14670354 general transcription factor II, i isoform 3 [Homo s...   442   e-124
gi|7662294 EPM2A interacting protein 1 [Homo sapiens]                 205   1e-52
gi|7705387 GTF2I repeat domain containing 1 isoform 1 [Homo sapi...   181   3e-45
gi|15011924 GTF2I repeat domain containing 1 isoform 2 [Homo sap...   181   3e-45
gi|46195755 SCAN domain containing 3 [Homo sapiens]                   156   8e-38
gi|115511046 zinc finger protein 258 [Homo sapiens]                   156   1e-37
gi|219521826 zinc finger, BED-type containing 5 [Homo sapiens]        155   1e-37
gi|49574210 zinc finger, BED-type containing 5 [Homo sapiens]         155   1e-37
gi|239746033 PREDICTED: hypothetical protein XP_002344174 [Homo ...   149   2e-35
gi|223633919 hypothetical protein LOC285550 [Homo sapiens]            146   8e-35
gi|28916698 transposon-derived Buster3 transposase-like [Homo sa...   145   1e-34
gi|21495178 hypothetical protein LOC221786 [Homo sapiens]             135   2e-31
gi|239757552 PREDICTED: similar to hCG2006635, partial [Homo sap...   118   2e-26
gi|239752592 PREDICTED: hypothetical protein XP_002348308, parti...   118   3e-26
gi|239754606 PREDICTED: similar to hCG1983816 [Homo sapiens]           88   4e-17
gi|239749152 PREDICTED: similar to hCG1983816 [Homo sapiens]           88   4e-17
gi|239508897 PREDICTED: similar to hCG1983816 [Homo sapiens]           88   4e-17
gi|239741279 PREDICTED: similar to FLJ00310 protein [Homo sapiens]     42   0.002
gi|116174778 centrosome spindle pole associated protein 1 isofor...    35   0.43 
gi|116174789 centrosome spindle pole associated protein 1 isofor...    35   0.43 
gi|19923268 protein-kinase, interferon-inducible double stranded...    34   0.57 
gi|31982906 cingulin-like 1 [Homo sapiens]                             34   0.74 
gi|171543895 ataxin 2 [Homo sapiens]                                   33   0.97 
gi|155969693 myomesin family, member 3 [Homo sapiens]                  33   1.3  
gi|47132519 Ras association and pleckstrin homology domains 1 is...    33   1.3  

>gi|48762700 GTF2I repeat domain containing 2 [Homo sapiens]
          Length = 949

 Score = 1904 bits (4932), Expect = 0.0
 Identities = 949/949 (100%), Positives = 949/949 (100%)

Query: 1   MAQVAVSTLPVEEESSSETRMVVTFLVSALESMCKELAKSKAEVACIAVYETDVFVVGTE 60
           MAQVAVSTLPVEEESSSETRMVVTFLVSALESMCKELAKSKAEVACIAVYETDVFVVGTE
Sbjct: 1   MAQVAVSTLPVEEESSSETRMVVTFLVSALESMCKELAKSKAEVACIAVYETDVFVVGTE 60

Query: 61  RGCAFVNARTDFQKDFAKYCVAEGLCEVKPPCPVNGMQVHSGETEILRKAVEDYFCFCYG 120
           RGCAFVNARTDFQKDFAKYCVAEGLCEVKPPCPVNGMQVHSGETEILRKAVEDYFCFCYG
Sbjct: 61  RGCAFVNARTDFQKDFAKYCVAEGLCEVKPPCPVNGMQVHSGETEILRKAVEDYFCFCYG 120

Query: 121 KALGTTVMVPVPYEKMLRDQSAVVVQGLPEGVAFQHPENYDLATLKWILENKAGISFIIN 180
           KALGTTVMVPVPYEKMLRDQSAVVVQGLPEGVAFQHPENYDLATLKWILENKAGISFIIN
Sbjct: 121 KALGTTVMVPVPYEKMLRDQSAVVVQGLPEGVAFQHPENYDLATLKWILENKAGISFIIN 180

Query: 181 RPFLGPESQLGGPGMVTDAERSIVSPSESCGPINVKTEPMEDSGISLKAEAVSVKKESED 240
           RPFLGPESQLGGPGMVTDAERSIVSPSESCGPINVKTEPMEDSGISLKAEAVSVKKESED
Sbjct: 181 RPFLGPESQLGGPGMVTDAERSIVSPSESCGPINVKTEPMEDSGISLKAEAVSVKKESED 240

Query: 241 PNYYQYNMQGSHPSSTSNEVIEMELPMEDSTPLVPSEEPNEDPEAEVKIEGNTNSSSVTN 300
           PNYYQYNMQGSHPSSTSNEVIEMELPMEDSTPLVPSEEPNEDPEAEVKIEGNTNSSSVTN
Sbjct: 241 PNYYQYNMQGSHPSSTSNEVIEMELPMEDSTPLVPSEEPNEDPEAEVKIEGNTNSSSVTN 300

Query: 301 SAAGVEDLNIVQVTVPDNEKERLSSIEKIKQLREQVNDLFSRKFGEAIGVDFPVKVPYRK 360
           SAAGVEDLNIVQVTVPDNEKERLSSIEKIKQLREQVNDLFSRKFGEAIGVDFPVKVPYRK
Sbjct: 301 SAAGVEDLNIVQVTVPDNEKERLSSIEKIKQLREQVNDLFSRKFGEAIGVDFPVKVPYRK 360

Query: 361 ITFNPGCVVIDGMPPGVVFKAPGYLEISSMRRILEAAEFIKFTVIRPLPGLELSNVGKRK 420
           ITFNPGCVVIDGMPPGVVFKAPGYLEISSMRRILEAAEFIKFTVIRPLPGLELSNVGKRK
Sbjct: 361 ITFNPGCVVIDGMPPGVVFKAPGYLEISSMRRILEAAEFIKFTVIRPLPGLELSNVGKRK 420

Query: 421 IDQEGRVFQEKWERAYFFVEVQNIPTCLICKQSMSVSKEYNLRRHYQTNHSKHYDQYMER 480
           IDQEGRVFQEKWERAYFFVEVQNIPTCLICKQSMSVSKEYNLRRHYQTNHSKHYDQYMER
Sbjct: 421 IDQEGRVFQEKWERAYFFVEVQNIPTCLICKQSMSVSKEYNLRRHYQTNHSKHYDQYMER 480

Query: 481 MRDEKLHELKKGLRKYLLGLSDTECPEQKQVFAHPSPTQKSPVQPVEDLAGNLWEKLREK 540
           MRDEKLHELKKGLRKYLLGLSDTECPEQKQVFAHPSPTQKSPVQPVEDLAGNLWEKLREK
Sbjct: 481 MRDEKLHELKKGLRKYLLGLSDTECPEQKQVFAHPSPTQKSPVQPVEDLAGNLWEKLREK 540

Query: 541 IRSFVAYSIAIDEITDINNTTQLAIFIRGVDENFDVSEELLDTVPMTGTKSGNEIFSRVE 600
           IRSFVAYSIAIDEITDINNTTQLAIFIRGVDENFDVSEELLDTVPMTGTKSGNEIFSRVE
Sbjct: 541 IRSFVAYSIAIDEITDINNTTQLAIFIRGVDENFDVSEELLDTVPMTGTKSGNEIFSRVE 600

Query: 601 KSLKKFCIDWSKLVSVASTGTPAMVDANNGLVTKLKSRVATFCKGAELKSICCIIHPESL 660
           KSLKKFCIDWSKLVSVASTGTPAMVDANNGLVTKLKSRVATFCKGAELKSICCIIHPESL
Sbjct: 601 KSLKKFCIDWSKLVSVASTGTPAMVDANNGLVTKLKSRVATFCKGAELKSICCIIHPESL 660

Query: 661 CAQKLKMDHVMDVVVKSVNWICSRGLNHSEFTTLLYELDSQYGSLLYYTEIKWLSRGLVL 720
           CAQKLKMDHVMDVVVKSVNWICSRGLNHSEFTTLLYELDSQYGSLLYYTEIKWLSRGLVL
Sbjct: 661 CAQKLKMDHVMDVVVKSVNWICSRGLNHSEFTTLLYELDSQYGSLLYYTEIKWLSRGLVL 720

Query: 721 KRFFESLEEIDSFMSSRGKPLPQLSSIDWIRDLAFLVDMTMHLNALNISLQGHSQIVTQM 780
           KRFFESLEEIDSFMSSRGKPLPQLSSIDWIRDLAFLVDMTMHLNALNISLQGHSQIVTQM
Sbjct: 721 KRFFESLEEIDSFMSSRGKPLPQLSSIDWIRDLAFLVDMTMHLNALNISLQGHSQIVTQM 780

Query: 781 YDLIRAFLAKLCLWETHLTRNNLAHFPTLKLASRNESDGLNYIPKIAELKTEFQKRLSDF 840
           YDLIRAFLAKLCLWETHLTRNNLAHFPTLKLASRNESDGLNYIPKIAELKTEFQKRLSDF
Sbjct: 781 YDLIRAFLAKLCLWETHLTRNNLAHFPTLKLASRNESDGLNYIPKIAELKTEFQKRLSDF 840

Query: 841 KLYESELTLFSSPFSTKIDSVHEELQMEVIDLQCNTVLKTKYDKVGIPEFYKYLWGSYPK 900
           KLYESELTLFSSPFSTKIDSVHEELQMEVIDLQCNTVLKTKYDKVGIPEFYKYLWGSYPK
Sbjct: 841 KLYESELTLFSSPFSTKIDSVHEELQMEVIDLQCNTVLKTKYDKVGIPEFYKYLWGSYPK 900

Query: 901 YKHHCAKILSMFGSTYICEQLFSIMKLSKTKYCSQLKDSQWDSVLHIAT 949
           YKHHCAKILSMFGSTYICEQLFSIMKLSKTKYCSQLKDSQWDSVLHIAT
Sbjct: 901 YKHHCAKILSMFGSTYICEQLFSIMKLSKTKYCSQLKDSQWDSVLHIAT 949


>gi|51241788 GTF2I repeat domain containing 2B [Homo sapiens]
          Length = 949

 Score = 1890 bits (4895), Expect = 0.0
 Identities = 942/949 (99%), Positives = 945/949 (99%)

Query: 1   MAQVAVSTLPVEEESSSETRMVVTFLVSALESMCKELAKSKAEVACIAVYETDVFVVGTE 60
           MAQVAVSTLPVEEESSSETRMVVTFLVSALESMCKELAKSKAEVACIAVYETDVFVVGTE
Sbjct: 1   MAQVAVSTLPVEEESSSETRMVVTFLVSALESMCKELAKSKAEVACIAVYETDVFVVGTE 60

Query: 61  RGCAFVNARTDFQKDFAKYCVAEGLCEVKPPCPVNGMQVHSGETEILRKAVEDYFCFCYG 120
           RGCAFVNARTDFQKDFAKYCVAEGLCEVKPPCPVNGMQVHSGETEILRKAVEDYFCFCYG
Sbjct: 61  RGCAFVNARTDFQKDFAKYCVAEGLCEVKPPCPVNGMQVHSGETEILRKAVEDYFCFCYG 120

Query: 121 KALGTTVMVPVPYEKMLRDQSAVVVQGLPEGVAFQHPENYDLATLKWILENKAGISFIIN 180
           KALGTTVMVPVPYEKMLRDQSAVVVQGLPEGVAFQHPENYDLATLKWILENKAGISFIIN
Sbjct: 121 KALGTTVMVPVPYEKMLRDQSAVVVQGLPEGVAFQHPENYDLATLKWILENKAGISFIIN 180

Query: 181 RPFLGPESQLGGPGMVTDAERSIVSPSESCGPINVKTEPMEDSGISLKAEAVSVKKESED 240
           RPFLGPESQLGGPGMVTDAERSIVSPSESCGPINVKTEPMEDSGISLKAEAVSVKKESED
Sbjct: 181 RPFLGPESQLGGPGMVTDAERSIVSPSESCGPINVKTEPMEDSGISLKAEAVSVKKESED 240

Query: 241 PNYYQYNMQGSHPSSTSNEVIEMELPMEDSTPLVPSEEPNEDPEAEVKIEGNTNSSSVTN 300
           PNYYQYNMQGSHPSSTSNEVIEMELPMEDSTPLVPSEEPNEDPEAEVKIEGNTNSSSVTN
Sbjct: 241 PNYYQYNMQGSHPSSTSNEVIEMELPMEDSTPLVPSEEPNEDPEAEVKIEGNTNSSSVTN 300

Query: 301 SAAGVEDLNIVQVTVPDNEKERLSSIEKIKQLREQVNDLFSRKFGEAIGVDFPVKVPYRK 360
           SAAGVEDLNIVQVTVPDNEKERLSSIEKIKQLREQVNDLFSRKFGEAIGVDFPVKVPYRK
Sbjct: 301 SAAGVEDLNIVQVTVPDNEKERLSSIEKIKQLREQVNDLFSRKFGEAIGVDFPVKVPYRK 360

Query: 361 ITFNPGCVVIDGMPPGVVFKAPGYLEISSMRRILEAAEFIKFTVIRPLPGLELSNVGKRK 420
           ITFNPGCVVIDGMPPGVVFKAPGYLEISSMRRILEAAEFIKFTVIRPLPGLELSNVGKRK
Sbjct: 361 ITFNPGCVVIDGMPPGVVFKAPGYLEISSMRRILEAAEFIKFTVIRPLPGLELSNVGKRK 420

Query: 421 IDQEGRVFQEKWERAYFFVEVQNIPTCLICKQSMSVSKEYNLRRHYQTNHSKHYDQYMER 480
           IDQEGRVFQEKWERAYFFVEVQNIPTCLICKQSMSVSKEYNLRRHYQTNHSKHYDQY ER
Sbjct: 421 IDQEGRVFQEKWERAYFFVEVQNIPTCLICKQSMSVSKEYNLRRHYQTNHSKHYDQYTER 480

Query: 481 MRDEKLHELKKGLRKYLLGLSDTECPEQKQVFAHPSPTQKSPVQPVEDLAGNLWEKLREK 540
           MRDEKLHELKKGLRKYLLG SDTECPEQKQVFA+PSPTQKSPVQPVEDLAGNLWEKLREK
Sbjct: 481 MRDEKLHELKKGLRKYLLGSSDTECPEQKQVFANPSPTQKSPVQPVEDLAGNLWEKLREK 540

Query: 541 IRSFVAYSIAIDEITDINNTTQLAIFIRGVDENFDVSEELLDTVPMTGTKSGNEIFSRVE 600
           IRSFVAYSIAIDEITDINNTTQLAIFIRGVDENFDVSEELLDTVPMTGTKSGNEIF RVE
Sbjct: 541 IRSFVAYSIAIDEITDINNTTQLAIFIRGVDENFDVSEELLDTVPMTGTKSGNEIFLRVE 600

Query: 601 KSLKKFCIDWSKLVSVASTGTPAMVDANNGLVTKLKSRVATFCKGAELKSICCIIHPESL 660
           KSLKKFCI+WS+LVSVASTGTPAMVDANNGLVTKLKSRVATFCKGAELKSICCIIHPESL
Sbjct: 601 KSLKKFCINWSRLVSVASTGTPAMVDANNGLVTKLKSRVATFCKGAELKSICCIIHPESL 660

Query: 661 CAQKLKMDHVMDVVVKSVNWICSRGLNHSEFTTLLYELDSQYGSLLYYTEIKWLSRGLVL 720
           CAQKLKMDHVMDVVVKSVNWICSRGLNHSEFTTLLYELDSQYGSLLYYTEIKWLSRGLVL
Sbjct: 661 CAQKLKMDHVMDVVVKSVNWICSRGLNHSEFTTLLYELDSQYGSLLYYTEIKWLSRGLVL 720

Query: 721 KRFFESLEEIDSFMSSRGKPLPQLSSIDWIRDLAFLVDMTMHLNALNISLQGHSQIVTQM 780
           KRFFESLEEIDSFMSSRGKPLPQLSSIDWIRDLAFLVDMTMHLNALNISLQGHSQIVTQM
Sbjct: 721 KRFFESLEEIDSFMSSRGKPLPQLSSIDWIRDLAFLVDMTMHLNALNISLQGHSQIVTQM 780

Query: 781 YDLIRAFLAKLCLWETHLTRNNLAHFPTLKLASRNESDGLNYIPKIAELKTEFQKRLSDF 840
           YDLIRAFLAKLCLWETHLTRNNLAHFPTLKL SRNESDGLNYIPKIAELKTEFQKRLSDF
Sbjct: 781 YDLIRAFLAKLCLWETHLTRNNLAHFPTLKLVSRNESDGLNYIPKIAELKTEFQKRLSDF 840

Query: 841 KLYESELTLFSSPFSTKIDSVHEELQMEVIDLQCNTVLKTKYDKVGIPEFYKYLWGSYPK 900
           KLYESELTLFSSPFSTKIDSVHEELQMEVIDLQCNTVLKTKYDKVGIPEFYKYLWGSYPK
Sbjct: 841 KLYESELTLFSSPFSTKIDSVHEELQMEVIDLQCNTVLKTKYDKVGIPEFYKYLWGSYPK 900

Query: 901 YKHHCAKILSMFGSTYICEQLFSIMKLSKTKYCSQLKDSQWDSVLHIAT 949
           YKHHCAKILSMFGSTYICEQLFSIMKLSKTKYCSQLKDSQWDSVLHIAT
Sbjct: 901 YKHHCAKILSMFGSTYICEQLFSIMKLSKTKYCSQLKDSQWDSVLHIAT 949


>gi|14670352 general transcription factor II, i isoform 2 [Homo
           sapiens]
          Length = 978

 Score =  472 bits (1215), Expect = e-133
 Identities = 265/448 (59%), Positives = 313/448 (69%), Gaps = 25/448 (5%)

Query: 1   MAQVAVSTLPVEEESSSETRMVVTFLVSALESMCKELAKSKAEVACIAVYETDVFVVGTE 60
           MAQVA+STLPVE+E SSE+RMVVTFL+SALESMCKELAKSKAEVACIAVYETDVFVVGTE
Sbjct: 1   MAQVAMSTLPVEDEESSESRMVVTFLMSALESMCKELAKSKAEVACIAVYETDVFVVGTE 60

Query: 61  RGCAFVNARTDFQKDFAKYCVAEG-----LCEVKPPCPVNGMQVHSGETEILRKAVEDYF 115
           RG AFVN R DFQKDF KYCV E      + ++K     N M V + E E LRK VEDYF
Sbjct: 61  RGRAFVNTRKDFQKDFVKYCVEEEEKAAEMHKMKSTTQANRMSVDAVEIETLRKTVEDYF 120

Query: 116 CFCYGKALGTTVMVPVPYEKMLRDQSAVVVQGLPEGVAFQHPENYDLATLKWILENKAGI 175
           CFCYGKALG + +VPVPYEKMLRDQSAVVVQGLPEGVAF+HPENYDLATLKWILENKAGI
Sbjct: 121 CFCYGKALGKSTVVPVPYEKMLRDQSAVVVQGLPEGVAFKHPENYDLATLKWILENKAGI 180

Query: 176 SFIINRPFLGPESQLGGPGMVTDAERSIVSPSESCGPINVKTEPMEDSGISLKAEAVSVK 235
           SFII RPFL P+  +GG  MVTDA+RSI+SP  SCGPI VKTEP EDSGISL+  AV+VK
Sbjct: 181 SFIIKRPFLEPKKHVGGRVMVTDADRSILSPGGSCGPIKVKTEPTEDSGISLEMAAVTVK 240

Query: 236 KESEDPNYYQYNMQGSHPSSTSNEVIEMELPMEDSTPLVPSEEPNEDPEAEVKIEGNTNS 295
           +ESEDP+YYQYN+QGSH SS  NE  EME+P EDST  VPS E +EDPE EV IE +  S
Sbjct: 241 EESEDPDYYQYNIQGSHHSSEGNEGTEMEVPAEDSTQHVPS-ETSEDPEVEVTIEDDDYS 299

Query: 296 SSVTNSAAGVEDLNIVQVTVPD-----NEKERLSSIEK----IKQLREQVNDLFSRKFGE 346
                  A      + Q  VP+       K R  + EK    I  LR+QV +LF RK+ +
Sbjct: 300 PPSKRPKAN----ELPQPPVPEPANAGKRKVREFNFEKWNARITDLRKQVEELFERKYAQ 355

Query: 347 AIGVDFPVKVPYRKITFNPGCVVIDGMPPGVVFKAPGYLEISSMRRILEAAEFIKFTVIR 406
           AI    PV +PY     +   + ++G+P G+ F+ P    I  + RIL A E I+F + +
Sbjct: 356 AIKAKGPVTIPYPLFQSHVEDLYVEGLPEGIPFRRPSTYGIPRLERILLAKERIRFVIKK 415

Query: 407 PLPGLELSNVGKR--KIDQEGRVFQEKW 432
                EL N  +   ++D+     +E+W
Sbjct: 416 H----ELLNSTREDLQLDKPASGVKEEW 439



 Score =  205 bits (521), Expect = 2e-52
 Identities = 100/140 (71%), Positives = 118/140 (84%)

Query: 294 NSSSVTNSAAGVEDLNIVQVTVPDNEKERLSSIEKIKQLREQVNDLFSRKFGEAIGVDFP 353
           +S +V  +A+GVEDLNI+QVT+PD++ ERLS +EK +QLREQVNDLFSRKFGEAIG+ FP
Sbjct: 810 SSPNVNTTASGVEDLNIIQVTIPDDDNERLSKVEKARQLREQVNDLFSRKFGEAIGMGFP 869

Query: 354 VKVPYRKITFNPGCVVIDGMPPGVVFKAPGYLEISSMRRILEAAEFIKFTVIRPLPGLEL 413
           VKVPYRKIT NPGCVV+DGMPPGV FKAP YLEISSMRRIL++AEFIKFTVIRP PGL +
Sbjct: 870 VKVPYRKITINPGCVVVDGMPPGVSFKAPSYLEISSMRRILDSAEFIKFTVIRPFPGLVI 929

Query: 414 SNVGKRKIDQEGRVFQEKWE 433
           +N    + + EG V QE  E
Sbjct: 930 NNQLVDQSESEGPVIQESAE 949



 Score = 90.1 bits (222), Expect = 9e-18
 Identities = 83/305 (27%), Positives = 131/305 (42%), Gaps = 23/305 (7%)

Query: 107 LRKAVEDYFCFCYGKALGTTVMVPVPYEKMLRDQSAVVVQGLPEGVAFQHPENYDLATLK 166
           LRK VE+ F   Y +A+     V +PY         + V+GLPEG+ F+ P  Y +  L+
Sbjct: 341 LRKQVEELFERKYAQAIKAKGPVTIPYPLFQSHVEDLYVEGLPEGIPFRRPSTYGIPRLE 400

Query: 167 WILENKAGISFIINRPFLGPESQLGGPGMVTDAERSIVSPSESCGPINVKTEPMEDSGIS 226
            IL  K  I F+I +  L     L         ++      E       K   M D    
Sbjct: 401 RILLAKERIRFVIKKHEL-----LNSTREDLQLDKPASGVKEEWYARITKLRKMVDQLFC 455

Query: 227 LK-AEAVSVKKESEDPNYYQYNMQGSHPSSTSNEVIEMELPMEDSTPLVPSEEPN--EDP 283
            K AEA+   +    P    Y    +HP+         +L +E     +P   P+    P
Sbjct: 456 KKFAEALGSTEAKAVP----YQKFEAHPN---------DLYVEGLPENIPFRSPSWYGIP 502

Query: 284 EAEVKIEGNTNSSSVTNSAAGVEDLNIVQVTVP-DNEKERLSSIEKIKQLREQVNDLFSR 342
             E  I+       V      +   +  +VT P  N   +     +I +LR+QV ++F+ 
Sbjct: 503 RLEKIIQVGNRIKFVIKRPELLTH-STTEVTQPRTNTPVKEDWNVRITKLRKQVEEIFNL 561

Query: 343 KFGEAIGVDFPVKVPYRKITFNPGCVVIDGMPPGVVFKAPGYLEISSMRRILEAAEFIKF 402
           KF +A+G+   VKVPY     NP  + ++G+P G+ F++P +  I  + RI+  +  IKF
Sbjct: 562 KFAQALGLTEAVKVPYPVFESNPEFLYVEGLPEGIPFRSPTWFGIPRLERIVRGSNKIKF 621

Query: 403 TVIRP 407
            V +P
Sbjct: 622 VVKKP 626



 Score = 67.0 bits (162), Expect = 8e-11
 Identities = 43/129 (33%), Positives = 65/129 (50%), Gaps = 6/129 (4%)

Query: 283 PEAEVKIEGNTNSSSVTNSAAGVEDLNIVQVTVPDNEKERLSSIE----KIKQLREQVND 338
           PE EV +EG  N++  T++       N     VP   + R  S E    KI  L+++V +
Sbjct: 662 PEIEVTVEGPNNNNPQTSAVRTPTQTN--GSNVPFKPRGREFSFEAWNAKITDLKQKVEN 719

Query: 339 LFSRKFGEAIGVDFPVKVPYRKITFNPGCVVIDGMPPGVVFKAPGYLEISSMRRILEAAE 398
           LF+ K GEA+G+   VKVP+      P    ++G+P GV F+ P    I  + +IL    
Sbjct: 720 LFNEKCGEALGLKQAVKVPFALFESFPEDFYVEGLPEGVPFRRPSTFGIPRLEKILRNKA 779

Query: 399 FIKFTVIRP 407
            IKF + +P
Sbjct: 780 KIKFIIKKP 788



 Score = 65.9 bits (159), Expect = 2e-10
 Identities = 47/144 (32%), Positives = 73/144 (50%), Gaps = 20/144 (13%)

Query: 107 LRKAVEDYFCFCYGKALGTTVMVPVPYEKMLRDQSAVVVQGLPEGVAFQHPENYDLATLK 166
           LR+ V D F   +G+A+G    V VPY K+  +   VVV G+P GV+F+ P   ++++++
Sbjct: 848 LREQVNDLFSRKFGEAIGMGFPVKVPYRKITINPGCVVVDGMPPGVSFKAPSYLEISSMR 907

Query: 167 WILENKAGISFIINRPFLGPESQLGGPGMVTDAERSIVSPSESCGPINVKTEPMEDSGIS 226
            IL++   I F + RPF         PG+V +    +V  SES GP  V  E  E S + 
Sbjct: 908 RILDSAEFIKFTVIRPF---------PGLVIN--NQLVDQSESEGP--VIQESAEPSQLE 954

Query: 227 LKA-------EAVSVKKESEDPNY 243
           + A       +  S  K+  DP +
Sbjct: 955 VPATEEIKETDGSSQIKQEPDPTW 978



 Score = 55.1 bits (131), Expect = 3e-07
 Identities = 31/76 (40%), Positives = 42/76 (55%)

Query: 107 LRKAVEDYFCFCYGKALGTTVMVPVPYEKMLRDQSAVVVQGLPEGVAFQHPENYDLATLK 166
           L++ VE+ F    G+ALG    V VP+           V+GLPEGV F+ P  + +  L+
Sbjct: 713 LKQKVENLFNEKCGEALGLKQAVKVPFALFESFPEDFYVEGLPEGVPFRRPSTFGIPRLE 772

Query: 167 WILENKAGISFIINRP 182
            IL NKA I FII +P
Sbjct: 773 KILRNKAKIKFIIKKP 788


>gi|14670350 general transcription factor II, i isoform 1 [Homo
           sapiens]
          Length = 998

 Score =  461 bits (1185), Expect = e-129
 Identities = 265/468 (56%), Positives = 313/468 (66%), Gaps = 45/468 (9%)

Query: 1   MAQVAVSTLPVEEESSSETRMVVTFLVSALESMCKELAKSKAEVACIAVYETDVFVVGTE 60
           MAQVA+STLPVE+E SSE+RMVVTFL+SALESMCKELAKSKAEVACIAVYETDVFVVGTE
Sbjct: 1   MAQVAMSTLPVEDEESSESRMVVTFLMSALESMCKELAKSKAEVACIAVYETDVFVVGTE 60

Query: 61  RGCAFVNARTDFQKDFAKYCVAEG-----LCEVKPPCPVNGMQVHSGETEILRKAVEDYF 115
           RG AFVN R DFQKDF KYCV E      + ++K     N M V + E E LRK VEDYF
Sbjct: 61  RGRAFVNTRKDFQKDFVKYCVEEEEKAAEMHKMKSTTQANRMSVDAVEIETLRKTVEDYF 120

Query: 116 CFCYGKALGTTVMVPVPYEKMLRDQSAVVVQGLPEGVAFQHPENYDLATLKWILENKAGI 175
           CFCYGKALG + +VPVPYEKMLRDQSAVVVQGLPEGVAF+HPENYDLATLKWILENKAGI
Sbjct: 121 CFCYGKALGKSTVVPVPYEKMLRDQSAVVVQGLPEGVAFKHPENYDLATLKWILENKAGI 180

Query: 176 SFIINRPFLGPESQLGGPGMVTDAERSIVSPSESCGPINVKTEPMEDSGISLKAEAVSVK 235
           SFII RPFL P+  +GG  MVTDA+RSI+SP  SCGPI VKTEP EDSGISL+  AV+VK
Sbjct: 181 SFIIKRPFLEPKKHVGGRVMVTDADRSILSPGGSCGPIKVKTEPTEDSGISLEMAAVTVK 240

Query: 236 KESEDPNYYQYN--------------------MQGSHPSSTSNEVIEMELPMEDSTPLVP 275
           +ESEDP+YYQYN                    +QGSH SS  NE  EME+P EDST  VP
Sbjct: 241 EESEDPDYYQYNIQAGPSETDDVDEKQPLSKPLQGSHHSSEGNEGTEMEVPAEDSTQHVP 300

Query: 276 SEEPNEDPEAEVKIEGNTNSSSVTNSAAGVEDLNIVQVTVPD-----NEKERLSSIEK-- 328
           S E +EDPE EV IE +  S       A      + Q  VP+       K R  + EK  
Sbjct: 301 S-ETSEDPEVEVTIEDDDYSPPSKRPKAN----ELPQPPVPEPANAGKRKVREFNFEKWN 355

Query: 329 --IKQLREQVNDLFSRKFGEAIGVDFPVKVPYRKITFNPGCVVIDGMPPGVVFKAPGYLE 386
             I  LR+QV +LF RK+ +AI    PV +PY     +   + ++G+P G+ F+ P    
Sbjct: 356 ARITDLRKQVEELFERKYAQAIKAKGPVTIPYPLFQSHVEDLYVEGLPEGIPFRRPSTYG 415

Query: 387 ISSMRRILEAAEFIKFTVIRPLPGLELSNVGKR--KIDQEGRVFQEKW 432
           I  + RIL A E I+F + +     EL N  +   ++D+     +E+W
Sbjct: 416 IPRLERILLAKERIRFVIKKH----ELLNSTREDLQLDKPASGVKEEW 459



 Score =  205 bits (521), Expect = 2e-52
 Identities = 100/140 (71%), Positives = 118/140 (84%)

Query: 294 NSSSVTNSAAGVEDLNIVQVTVPDNEKERLSSIEKIKQLREQVNDLFSRKFGEAIGVDFP 353
           +S +V  +A+GVEDLNI+QVT+PD++ ERLS +EK +QLREQVNDLFSRKFGEAIG+ FP
Sbjct: 830 SSPNVNTTASGVEDLNIIQVTIPDDDNERLSKVEKARQLREQVNDLFSRKFGEAIGMGFP 889

Query: 354 VKVPYRKITFNPGCVVIDGMPPGVVFKAPGYLEISSMRRILEAAEFIKFTVIRPLPGLEL 413
           VKVPYRKIT NPGCVV+DGMPPGV FKAP YLEISSMRRIL++AEFIKFTVIRP PGL +
Sbjct: 890 VKVPYRKITINPGCVVVDGMPPGVSFKAPSYLEISSMRRILDSAEFIKFTVIRPFPGLVI 949

Query: 414 SNVGKRKIDQEGRVFQEKWE 433
           +N    + + EG V QE  E
Sbjct: 950 NNQLVDQSESEGPVIQESAE 969



 Score = 90.1 bits (222), Expect = 9e-18
 Identities = 83/305 (27%), Positives = 131/305 (42%), Gaps = 23/305 (7%)

Query: 107 LRKAVEDYFCFCYGKALGTTVMVPVPYEKMLRDQSAVVVQGLPEGVAFQHPENYDLATLK 166
           LRK VE+ F   Y +A+     V +PY         + V+GLPEG+ F+ P  Y +  L+
Sbjct: 361 LRKQVEELFERKYAQAIKAKGPVTIPYPLFQSHVEDLYVEGLPEGIPFRRPSTYGIPRLE 420

Query: 167 WILENKAGISFIINRPFLGPESQLGGPGMVTDAERSIVSPSESCGPINVKTEPMEDSGIS 226
            IL  K  I F+I +  L     L         ++      E       K   M D    
Sbjct: 421 RILLAKERIRFVIKKHEL-----LNSTREDLQLDKPASGVKEEWYARITKLRKMVDQLFC 475

Query: 227 LK-AEAVSVKKESEDPNYYQYNMQGSHPSSTSNEVIEMELPMEDSTPLVPSEEPN--EDP 283
            K AEA+   +    P    Y    +HP+         +L +E     +P   P+    P
Sbjct: 476 KKFAEALGSTEAKAVP----YQKFEAHPN---------DLYVEGLPENIPFRSPSWYGIP 522

Query: 284 EAEVKIEGNTNSSSVTNSAAGVEDLNIVQVTVP-DNEKERLSSIEKIKQLREQVNDLFSR 342
             E  I+       V      +   +  +VT P  N   +     +I +LR+QV ++F+ 
Sbjct: 523 RLEKIIQVGNRIKFVIKRPELLTH-STTEVTQPRTNTPVKEDWNVRITKLRKQVEEIFNL 581

Query: 343 KFGEAIGVDFPVKVPYRKITFNPGCVVIDGMPPGVVFKAPGYLEISSMRRILEAAEFIKF 402
           KF +A+G+   VKVPY     NP  + ++G+P G+ F++P +  I  + RI+  +  IKF
Sbjct: 582 KFAQALGLTEAVKVPYPVFESNPEFLYVEGLPEGIPFRSPTWFGIPRLERIVRGSNKIKF 641

Query: 403 TVIRP 407
            V +P
Sbjct: 642 VVKKP 646



 Score = 67.0 bits (162), Expect = 8e-11
 Identities = 43/129 (33%), Positives = 65/129 (50%), Gaps = 6/129 (4%)

Query: 283 PEAEVKIEGNTNSSSVTNSAAGVEDLNIVQVTVPDNEKERLSSIE----KIKQLREQVND 338
           PE EV +EG  N++  T++       N     VP   + R  S E    KI  L+++V +
Sbjct: 682 PEIEVTVEGPNNNNPQTSAVRTPTQTN--GSNVPFKPRGREFSFEAWNAKITDLKQKVEN 739

Query: 339 LFSRKFGEAIGVDFPVKVPYRKITFNPGCVVIDGMPPGVVFKAPGYLEISSMRRILEAAE 398
           LF+ K GEA+G+   VKVP+      P    ++G+P GV F+ P    I  + +IL    
Sbjct: 740 LFNEKCGEALGLKQAVKVPFALFESFPEDFYVEGLPEGVPFRRPSTFGIPRLEKILRNKA 799

Query: 399 FIKFTVIRP 407
            IKF + +P
Sbjct: 800 KIKFIIKKP 808



 Score = 65.9 bits (159), Expect = 2e-10
 Identities = 47/144 (32%), Positives = 73/144 (50%), Gaps = 20/144 (13%)

Query: 107 LRKAVEDYFCFCYGKALGTTVMVPVPYEKMLRDQSAVVVQGLPEGVAFQHPENYDLATLK 166
           LR+ V D F   +G+A+G    V VPY K+  +   VVV G+P GV+F+ P   ++++++
Sbjct: 868 LREQVNDLFSRKFGEAIGMGFPVKVPYRKITINPGCVVVDGMPPGVSFKAPSYLEISSMR 927

Query: 167 WILENKAGISFIINRPFLGPESQLGGPGMVTDAERSIVSPSESCGPINVKTEPMEDSGIS 226
            IL++   I F + RPF         PG+V +    +V  SES GP  V  E  E S + 
Sbjct: 928 RILDSAEFIKFTVIRPF---------PGLVIN--NQLVDQSESEGP--VIQESAEPSQLE 974

Query: 227 LKA-------EAVSVKKESEDPNY 243
           + A       +  S  K+  DP +
Sbjct: 975 VPATEEIKETDGSSQIKQEPDPTW 998



 Score = 55.1 bits (131), Expect = 3e-07
 Identities = 31/76 (40%), Positives = 42/76 (55%)

Query: 107 LRKAVEDYFCFCYGKALGTTVMVPVPYEKMLRDQSAVVVQGLPEGVAFQHPENYDLATLK 166
           L++ VE+ F    G+ALG    V VP+           V+GLPEGV F+ P  + +  L+
Sbjct: 733 LKQKVENLFNEKCGEALGLKQAVKVPFALFESFPEDFYVEGLPEGVPFRRPSTFGIPRLE 792

Query: 167 WILENKAGISFIINRP 182
            IL NKA I FII +P
Sbjct: 793 KILRNKAKIKFIIKKP 808


>gi|169881252 general transcription factor II, i isoform 4 [Homo
           sapiens]
          Length = 957

 Score =  453 bits (1166), Expect = e-127
 Identities = 252/441 (57%), Positives = 300/441 (68%), Gaps = 32/441 (7%)

Query: 1   MAQVAVSTLPVEEESSSETRMVVTFLVSALESMCKELAKSKAEVACIAVYETDVFVVGTE 60
           MAQVA+STLPVE+E SSE+RMVVTFL+SALESMCKELAKSKAEVACIAVYETDVFVVGTE
Sbjct: 1   MAQVAMSTLPVEDEESSESRMVVTFLMSALESMCKELAKSKAEVACIAVYETDVFVVGTE 60

Query: 61  RGCAFVNARTDFQKDFAKYCVAEG-----LCEVKPPCPVNGMQVHSGETEILRKAVEDYF 115
           RG AFVN R DFQKDF KYCV E      + ++K     N M V + E E LRK VEDYF
Sbjct: 61  RGRAFVNTRKDFQKDFVKYCVEEEEKAAEMHKMKSTTQANRMSVDAVEIETLRKTVEDYF 120

Query: 116 CFCYGKALGTTVMVPVPYEKMLRDQSAVVVQGLPEGVAFQHPENYDLATLKWILENKAGI 175
           CFCYGKALG + +VPVPYEKMLRDQSAVVVQGLPEGVAF+HPENYDLATLKWILENKAGI
Sbjct: 121 CFCYGKALGKSTVVPVPYEKMLRDQSAVVVQGLPEGVAFKHPENYDLATLKWILENKAGI 180

Query: 176 SFIINRPFLGPESQLGGPGMVTDAERSIVSPSESCGPINVKTEPMEDSGISLKAEAVSVK 235
           SFII RPFL P+  +GG  MVTDA+RSI+SP  SCGPI VKTEP EDSGISL+  AV+VK
Sbjct: 181 SFIIKRPFLEPKKHVGGRVMVTDADRSILSPGGSCGPIKVKTEPTEDSGISLEMAAVTVK 240

Query: 236 KESEDPNYYQYNMQGSHPSSTSNEVIEMELPMEDSTPLVPSEEP--NEDPEAEVKIEGNT 293
           +ESEDP+YYQYN+QGSH SS  NE  EME+P ED     PS+ P  NE P+  V    N 
Sbjct: 241 EESEDPDYYQYNIQGSHHSSEGNEGTEMEVPAEDDDYSPPSKRPKANELPQPPVPEPANA 300

Query: 294 NSSSVTNSAAGVEDLNIVQVTVPDNEKERLSSIEKIKQLREQVNDLFSRKFGEAIGVDFP 353
                      V + N  +               +I  LR+QV +LF RK+ +AI    P
Sbjct: 301 GKRK-------VREFNFEKWNA------------RITDLRKQVEELFERKYAQAIKAKGP 341

Query: 354 VKVPYRKITFNPGCVVIDGMPPGVVFKAPGYLEISSMRRILEAAEFIKFTVIRPLPGLEL 413
           V +PY     +   + ++G+P G+ F+ P    I  + RIL A E I+F + +     EL
Sbjct: 342 VTIPYPLFQSHVEDLYVEGLPEGIPFRRPSTYGIPRLERILLAKERIRFVIKKH----EL 397

Query: 414 SNVGKR--KIDQEGRVFQEKW 432
            N  +   ++D+     +E+W
Sbjct: 398 LNSTREDLQLDKPASGVKEEW 418



 Score =  205 bits (521), Expect = 2e-52
 Identities = 100/140 (71%), Positives = 118/140 (84%)

Query: 294 NSSSVTNSAAGVEDLNIVQVTVPDNEKERLSSIEKIKQLREQVNDLFSRKFGEAIGVDFP 353
           +S +V  +A+GVEDLNI+QVT+PD++ ERLS +EK +QLREQVNDLFSRKFGEAIG+ FP
Sbjct: 789 SSPNVNTTASGVEDLNIIQVTIPDDDNERLSKVEKARQLREQVNDLFSRKFGEAIGMGFP 848

Query: 354 VKVPYRKITFNPGCVVIDGMPPGVVFKAPGYLEISSMRRILEAAEFIKFTVIRPLPGLEL 413
           VKVPYRKIT NPGCVV+DGMPPGV FKAP YLEISSMRRIL++AEFIKFTVIRP PGL +
Sbjct: 849 VKVPYRKITINPGCVVVDGMPPGVSFKAPSYLEISSMRRILDSAEFIKFTVIRPFPGLVI 908

Query: 414 SNVGKRKIDQEGRVFQEKWE 433
           +N    + + EG V QE  E
Sbjct: 909 NNQLVDQSESEGPVIQESAE 928



 Score = 90.1 bits (222), Expect = 9e-18
 Identities = 83/305 (27%), Positives = 131/305 (42%), Gaps = 23/305 (7%)

Query: 107 LRKAVEDYFCFCYGKALGTTVMVPVPYEKMLRDQSAVVVQGLPEGVAFQHPENYDLATLK 166
           LRK VE+ F   Y +A+     V +PY         + V+GLPEG+ F+ P  Y +  L+
Sbjct: 320 LRKQVEELFERKYAQAIKAKGPVTIPYPLFQSHVEDLYVEGLPEGIPFRRPSTYGIPRLE 379

Query: 167 WILENKAGISFIINRPFLGPESQLGGPGMVTDAERSIVSPSESCGPINVKTEPMEDSGIS 226
            IL  K  I F+I +  L     L         ++      E       K   M D    
Sbjct: 380 RILLAKERIRFVIKKHEL-----LNSTREDLQLDKPASGVKEEWYARITKLRKMVDQLFC 434

Query: 227 LK-AEAVSVKKESEDPNYYQYNMQGSHPSSTSNEVIEMELPMEDSTPLVPSEEPN--EDP 283
            K AEA+   +    P    Y    +HP+         +L +E     +P   P+    P
Sbjct: 435 KKFAEALGSTEAKAVP----YQKFEAHPN---------DLYVEGLPENIPFRSPSWYGIP 481

Query: 284 EAEVKIEGNTNSSSVTNSAAGVEDLNIVQVTVP-DNEKERLSSIEKIKQLREQVNDLFSR 342
             E  I+       V      +   +  +VT P  N   +     +I +LR+QV ++F+ 
Sbjct: 482 RLEKIIQVGNRIKFVIKRPELLTH-STTEVTQPRTNTPVKEDWNVRITKLRKQVEEIFNL 540

Query: 343 KFGEAIGVDFPVKVPYRKITFNPGCVVIDGMPPGVVFKAPGYLEISSMRRILEAAEFIKF 402
           KF +A+G+   VKVPY     NP  + ++G+P G+ F++P +  I  + RI+  +  IKF
Sbjct: 541 KFAQALGLTEAVKVPYPVFESNPEFLYVEGLPEGIPFRSPTWFGIPRLERIVRGSNKIKF 600

Query: 403 TVIRP 407
            V +P
Sbjct: 601 VVKKP 605



 Score = 67.0 bits (162), Expect = 8e-11
 Identities = 43/129 (33%), Positives = 65/129 (50%), Gaps = 6/129 (4%)

Query: 283 PEAEVKIEGNTNSSSVTNSAAGVEDLNIVQVTVPDNEKERLSSIE----KIKQLREQVND 338
           PE EV +EG  N++  T++       N     VP   + R  S E    KI  L+++V +
Sbjct: 641 PEIEVTVEGPNNNNPQTSAVRTPTQTN--GSNVPFKPRGREFSFEAWNAKITDLKQKVEN 698

Query: 339 LFSRKFGEAIGVDFPVKVPYRKITFNPGCVVIDGMPPGVVFKAPGYLEISSMRRILEAAE 398
           LF+ K GEA+G+   VKVP+      P    ++G+P GV F+ P    I  + +IL    
Sbjct: 699 LFNEKCGEALGLKQAVKVPFALFESFPEDFYVEGLPEGVPFRRPSTFGIPRLEKILRNKA 758

Query: 399 FIKFTVIRP 407
            IKF + +P
Sbjct: 759 KIKFIIKKP 767



 Score = 65.9 bits (159), Expect = 2e-10
 Identities = 47/144 (32%), Positives = 73/144 (50%), Gaps = 20/144 (13%)

Query: 107 LRKAVEDYFCFCYGKALGTTVMVPVPYEKMLRDQSAVVVQGLPEGVAFQHPENYDLATLK 166
           LR+ V D F   +G+A+G    V VPY K+  +   VVV G+P GV+F+ P   ++++++
Sbjct: 827 LREQVNDLFSRKFGEAIGMGFPVKVPYRKITINPGCVVVDGMPPGVSFKAPSYLEISSMR 886

Query: 167 WILENKAGISFIINRPFLGPESQLGGPGMVTDAERSIVSPSESCGPINVKTEPMEDSGIS 226
            IL++   I F + RPF         PG+V +    +V  SES GP  V  E  E S + 
Sbjct: 887 RILDSAEFIKFTVIRPF---------PGLVIN--NQLVDQSESEGP--VIQESAEPSQLE 933

Query: 227 LKA-------EAVSVKKESEDPNY 243
           + A       +  S  K+  DP +
Sbjct: 934 VPATEEIKETDGSSQIKQEPDPTW 957



 Score = 55.1 bits (131), Expect = 3e-07
 Identities = 31/76 (40%), Positives = 42/76 (55%)

Query: 107 LRKAVEDYFCFCYGKALGTTVMVPVPYEKMLRDQSAVVVQGLPEGVAFQHPENYDLATLK 166
           L++ VE+ F    G+ALG    V VP+           V+GLPEGV F+ P  + +  L+
Sbjct: 692 LKQKVENLFNEKCGEALGLKQAVKVPFALFESFPEDFYVEGLPEGVPFRRPSTFGIPRLE 751

Query: 167 WILENKAGISFIINRP 182
            IL NKA I FII +P
Sbjct: 752 KILRNKAKIKFIIKKP 767


>gi|14670354 general transcription factor II, i isoform 3 [Homo
           sapiens]
          Length = 977

 Score =  442 bits (1136), Expect = e-124
 Identities = 252/461 (54%), Positives = 300/461 (65%), Gaps = 52/461 (11%)

Query: 1   MAQVAVSTLPVEEESSSETRMVVTFLVSALESMCKELAKSKAEVACIAVYETDVFVVGTE 60
           MAQVA+STLPVE+E SSE+RMVVTFL+SALESMCKELAKSKAEVACIAVYETDVFVVGTE
Sbjct: 1   MAQVAMSTLPVEDEESSESRMVVTFLMSALESMCKELAKSKAEVACIAVYETDVFVVGTE 60

Query: 61  RGCAFVNARTDFQKDFAKYCVAEG-----LCEVKPPCPVNGMQVHSGETEILRKAVEDYF 115
           RG AFVN R DFQKDF KYCV E      + ++K     N M V + E E LRK VEDYF
Sbjct: 61  RGRAFVNTRKDFQKDFVKYCVEEEEKAAEMHKMKSTTQANRMSVDAVEIETLRKTVEDYF 120

Query: 116 CFCYGKALGTTVMVPVPYEKMLRDQSAVVVQGLPEGVAFQHPENYDLATLKWILENKAGI 175
           CFCYGKALG + +VPVPYEKMLRDQSAVVVQGLPEGVAF+HPENYDLATLKWILENKAGI
Sbjct: 121 CFCYGKALGKSTVVPVPYEKMLRDQSAVVVQGLPEGVAFKHPENYDLATLKWILENKAGI 180

Query: 176 SFIINRPFLGPESQLGGPGMVTDAERSIVSPSESCGPINVKTEPMEDSGISLKAEAVSVK 235
           SFII RPFL P+  +GG  MVTDA+RSI+SP  SCGPI VKTEP EDSGISL+  AV+VK
Sbjct: 181 SFIIKRPFLEPKKHVGGRVMVTDADRSILSPGGSCGPIKVKTEPTEDSGISLEMAAVTVK 240

Query: 236 KESEDPNYYQYN--------------------MQGSHPSSTSNEVIEMELPMEDSTPLVP 275
           +ESEDP+YYQYN                    +QGSH SS  NE  EME+P ED     P
Sbjct: 241 EESEDPDYYQYNIQAGPSETDDVDEKQPLSKPLQGSHHSSEGNEGTEMEVPAEDDDYSPP 300

Query: 276 SEEP--NEDPEAEVKIEGNTNSSSVTNSAAGVEDLNIVQVTVPDNEKERLSSIEKIKQLR 333
           S+ P  NE P+  V    N            V + N  +               +I  LR
Sbjct: 301 SKRPKANELPQPPVPEPANAGKRK-------VREFNFEKWNA------------RITDLR 341

Query: 334 EQVNDLFSRKFGEAIGVDFPVKVPYRKITFNPGCVVIDGMPPGVVFKAPGYLEISSMRRI 393
           +QV +LF RK+ +AI    PV +PY     +   + ++G+P G+ F+ P    I  + RI
Sbjct: 342 KQVEELFERKYAQAIKAKGPVTIPYPLFQSHVEDLYVEGLPEGIPFRRPSTYGIPRLERI 401

Query: 394 LEAAEFIKFTVIRPLPGLELSNVGKR--KIDQEGRVFQEKW 432
           L A E I+F + +     EL N  +   ++D+     +E+W
Sbjct: 402 LLAKERIRFVIKKH----ELLNSTREDLQLDKPASGVKEEW 438



 Score =  205 bits (521), Expect = 2e-52
 Identities = 100/140 (71%), Positives = 118/140 (84%)

Query: 294 NSSSVTNSAAGVEDLNIVQVTVPDNEKERLSSIEKIKQLREQVNDLFSRKFGEAIGVDFP 353
           +S +V  +A+GVEDLNI+QVT+PD++ ERLS +EK +QLREQVNDLFSRKFGEAIG+ FP
Sbjct: 809 SSPNVNTTASGVEDLNIIQVTIPDDDNERLSKVEKARQLREQVNDLFSRKFGEAIGMGFP 868

Query: 354 VKVPYRKITFNPGCVVIDGMPPGVVFKAPGYLEISSMRRILEAAEFIKFTVIRPLPGLEL 413
           VKVPYRKIT NPGCVV+DGMPPGV FKAP YLEISSMRRIL++AEFIKFTVIRP PGL +
Sbjct: 869 VKVPYRKITINPGCVVVDGMPPGVSFKAPSYLEISSMRRILDSAEFIKFTVIRPFPGLVI 928

Query: 414 SNVGKRKIDQEGRVFQEKWE 433
           +N    + + EG V QE  E
Sbjct: 929 NNQLVDQSESEGPVIQESAE 948



 Score = 90.1 bits (222), Expect = 9e-18
 Identities = 83/305 (27%), Positives = 131/305 (42%), Gaps = 23/305 (7%)

Query: 107 LRKAVEDYFCFCYGKALGTTVMVPVPYEKMLRDQSAVVVQGLPEGVAFQHPENYDLATLK 166
           LRK VE+ F   Y +A+     V +PY         + V+GLPEG+ F+ P  Y +  L+
Sbjct: 340 LRKQVEELFERKYAQAIKAKGPVTIPYPLFQSHVEDLYVEGLPEGIPFRRPSTYGIPRLE 399

Query: 167 WILENKAGISFIINRPFLGPESQLGGPGMVTDAERSIVSPSESCGPINVKTEPMEDSGIS 226
            IL  K  I F+I +  L     L         ++      E       K   M D    
Sbjct: 400 RILLAKERIRFVIKKHEL-----LNSTREDLQLDKPASGVKEEWYARITKLRKMVDQLFC 454

Query: 227 LK-AEAVSVKKESEDPNYYQYNMQGSHPSSTSNEVIEMELPMEDSTPLVPSEEPN--EDP 283
            K AEA+   +    P    Y    +HP+         +L +E     +P   P+    P
Sbjct: 455 KKFAEALGSTEAKAVP----YQKFEAHPN---------DLYVEGLPENIPFRSPSWYGIP 501

Query: 284 EAEVKIEGNTNSSSVTNSAAGVEDLNIVQVTVP-DNEKERLSSIEKIKQLREQVNDLFSR 342
             E  I+       V      +   +  +VT P  N   +     +I +LR+QV ++F+ 
Sbjct: 502 RLEKIIQVGNRIKFVIKRPELLTH-STTEVTQPRTNTPVKEDWNVRITKLRKQVEEIFNL 560

Query: 343 KFGEAIGVDFPVKVPYRKITFNPGCVVIDGMPPGVVFKAPGYLEISSMRRILEAAEFIKF 402
           KF +A+G+   VKVPY     NP  + ++G+P G+ F++P +  I  + RI+  +  IKF
Sbjct: 561 KFAQALGLTEAVKVPYPVFESNPEFLYVEGLPEGIPFRSPTWFGIPRLERIVRGSNKIKF 620

Query: 403 TVIRP 407
            V +P
Sbjct: 621 VVKKP 625



 Score = 67.0 bits (162), Expect = 8e-11
 Identities = 43/129 (33%), Positives = 65/129 (50%), Gaps = 6/129 (4%)

Query: 283 PEAEVKIEGNTNSSSVTNSAAGVEDLNIVQVTVPDNEKERLSSIE----KIKQLREQVND 338
           PE EV +EG  N++  T++       N     VP   + R  S E    KI  L+++V +
Sbjct: 661 PEIEVTVEGPNNNNPQTSAVRTPTQTN--GSNVPFKPRGREFSFEAWNAKITDLKQKVEN 718

Query: 339 LFSRKFGEAIGVDFPVKVPYRKITFNPGCVVIDGMPPGVVFKAPGYLEISSMRRILEAAE 398
           LF+ K GEA+G+   VKVP+      P    ++G+P GV F+ P    I  + +IL    
Sbjct: 719 LFNEKCGEALGLKQAVKVPFALFESFPEDFYVEGLPEGVPFRRPSTFGIPRLEKILRNKA 778

Query: 399 FIKFTVIRP 407
            IKF + +P
Sbjct: 779 KIKFIIKKP 787



 Score = 65.9 bits (159), Expect = 2e-10
 Identities = 47/144 (32%), Positives = 73/144 (50%), Gaps = 20/144 (13%)

Query: 107 LRKAVEDYFCFCYGKALGTTVMVPVPYEKMLRDQSAVVVQGLPEGVAFQHPENYDLATLK 166
           LR+ V D F   +G+A+G    V VPY K+  +   VVV G+P GV+F+ P   ++++++
Sbjct: 847 LREQVNDLFSRKFGEAIGMGFPVKVPYRKITINPGCVVVDGMPPGVSFKAPSYLEISSMR 906

Query: 167 WILENKAGISFIINRPFLGPESQLGGPGMVTDAERSIVSPSESCGPINVKTEPMEDSGIS 226
            IL++   I F + RPF         PG+V +    +V  SES GP  V  E  E S + 
Sbjct: 907 RILDSAEFIKFTVIRPF---------PGLVIN--NQLVDQSESEGP--VIQESAEPSQLE 953

Query: 227 LKA-------EAVSVKKESEDPNY 243
           + A       +  S  K+  DP +
Sbjct: 954 VPATEEIKETDGSSQIKQEPDPTW 977



 Score = 55.1 bits (131), Expect = 3e-07
 Identities = 31/76 (40%), Positives = 42/76 (55%)

Query: 107 LRKAVEDYFCFCYGKALGTTVMVPVPYEKMLRDQSAVVVQGLPEGVAFQHPENYDLATLK 166
           L++ VE+ F    G+ALG    V VP+           V+GLPEGV F+ P  + +  L+
Sbjct: 712 LKQKVENLFNEKCGEALGLKQAVKVPFALFESFPEDFYVEGLPEGVPFRRPSTFGIPRLE 771

Query: 167 WILENKAGISFIINRP 182
            IL NKA I FII +P
Sbjct: 772 KILRNKAKIKFIIKKP 787


>gi|7662294 EPM2A interacting protein 1 [Homo sapiens]
          Length = 607

 Score =  205 bits (522), Expect = 1e-52
 Identities = 162/584 (27%), Positives = 280/584 (47%), Gaps = 56/584 (9%)

Query: 418 KRKIDQEGRVFQEKWERAYFFVEVQ--NIPTCLICKQSMSVSKEYNLRRHYQTNHSKHYD 475
           K ++D E  VF+ +W + Y  VE    +   CL+C++ +  ++E ++RRHY+  H ++Y+
Sbjct: 9   KMEVD-EALVFRPEWTQRYLVVEPPEGDGALCLVCRRLIVATRERDVRRHYEAEH-EYYE 66

Query: 476 QYM---------ERMR-----------DEKLHELKKGLRKYLL------GLSDT--ECPE 507
           +Y+         ER+R           +E+      GL + L       G  D   +C E
Sbjct: 67  RYVADGERAALVERLRQGDLPVASFTPEERAARAGLGLCRLLALKGRGWGEGDFVYQCME 126

Query: 508 ---QKQVFAHPSPTQKSPVQP------VEDLAGNLWEKLREKIRSFVAYSIAIDEITDIN 558
              ++ +  H S  Q   + P      +  +  NL  +L  + R F AYS+A+D+   + 
Sbjct: 127 VLLREVLPEHVSVLQGVDLSPDITRQRILSIDRNLRNQLFNRARDFKAYSLALDDQAFVA 186

Query: 559 NTTQLAIFIRGVDENFDVSEELLDTVPMTGTKSGNEIFSRVEKSLKKFCIDWSKLVSVAS 618
               L +FIRGV    +V E+LL  + +T   S   + S + +SL+   +   ++V + +
Sbjct: 187 YENYLLVFIRGVGPELEVQEDLLTIINLTHHFSVGALMSAILESLQTAGLSLQRMVGLTT 246

Query: 619 TGTPAMVDANNGLVTKLKSR-VATFCKGAELKSICCIIHPESLCAQKLKMDHVMDVVVKS 677
           T T  M+  N+GLV+ ++ + V+  C      S    +H E L +  + ++ +++ + + 
Sbjct: 247 THTLRMIGENSGLVSYMREKAVSPNCWNVIHYS--GFLHLELLSSYDVDVNQIINTISEW 304

Query: 678 VNWICSRGLNHSEFTTLLYELDSQYGSLLYYTEIK-WLSRGLVLKRFFESLEEIDSFMSS 736
           +  I +RG+   EF TLL E +S++G  +    +  WL RG  LK  F   +E+++F+ S
Sbjct: 305 IVLIKTRGVRRPEFQTLLTESESEHGERVNGRCLNNWLRRGKTLKLIFSLRKEMEAFLVS 364

Query: 737 RGKPLPQLSSIDWIRDLAFLVDMTMHLNALNISLQGHSQIVTQMYDLIRAFLAKLCLWET 796
            G      S   W+ D  FLVD+  HL  L+  L+         +D I  F  KL L++ 
Sbjct: 365 VGATTVHFSDKQWLCDFGFLVDIMEHLRELSEELRVSKVFAAAAFDHICTFEVKLNLFQR 424

Query: 797 HLTRNNLAHFPTLK-----LASRNESDGLNYIPK-----IAELKTEFQKRLSDFKLYESE 846
           H+   NL  FP L+     L  +N+ D   + P      I  L+ EF++   D +  + +
Sbjct: 425 HIEEKNLTDFPALREVVDELKQQNKEDEKIFDPDRYQMVICRLQKEFERHFKDLRFIKKD 484

Query: 847 LTLFSSPFSTKIDSVHEELQMEVIDLQCNTVLKTKYDKVGIPEFYKYLWG-SYPKYKHHC 905
           L LFS+PF+ K +     +++E+  LQ NT L  +Y    + +FY  L   SYP  K   
Sbjct: 485 LELFSNPFNFKPEYAPISVRVELTKLQANTNLWNEYRIKDLGQFYAGLSAESYPIIKGVA 544

Query: 906 AKILSMFGSTYICEQLFSIMKLSKTKYCSQLKDSQWDSVLHIAT 949
            K+ S+F S  ICE+ FS +  ++      L D    ++  +AT
Sbjct: 545 CKVASLFDSNQICEKAFSYLTRNQHTLSQPLTDEHLQALFRVAT 588


>gi|7705387 GTF2I repeat domain containing 1 isoform 1 [Homo
           sapiens]
          Length = 959

 Score =  181 bits (459), Expect = 3e-45
 Identities = 131/412 (31%), Positives = 189/412 (45%), Gaps = 43/412 (10%)

Query: 22  VVTFLVSALESMCKELAKSKAEVACIAVYETDVFVVGTERGCAFVNARTDFQKDFAKYCV 81
           ++T LVSAL+SMC  L+K  AEVAC+AV++   FVVGTE+G  F+NAR + Q DF ++C 
Sbjct: 30  IITSLVSALDSMCSALSKLNAEVACVAVHDESAFVVGTEKGRMFLNARKELQSDFLRFCR 89

Query: 82  AEGLCEVKPPCPVNGMQ-------------VHSGETEILRKAVEDYFCFCYGKALGTTVM 128
                + +   P    +              H  +  +LRK VE+ F   Y +ALG   +
Sbjct: 90  GPPWKDPEAEHPKKVQRGEGGGRSLPRSSLEHGSDVYLLRKMVEEVFDVLYSEALGRASV 149

Query: 129 VPVPYEKMLRDQSAVVVQGLPEGVAFQHPENYDLATLKWILENKAGISFIINRPFLGPES 188
           VP+PYE++LR+   + VQGLPEG+AF+ P  YD   L  ILE+   I F + RP      
Sbjct: 150 VPLPYERLLREPGLLAVQGLPEGLAFRRPAEYDPKALMAILEHSHRIRFKLKRP------ 203

Query: 189 QLGGPGMVTDAERSIVSPSESCGPINVKTEPMEDSGISLKAEAVSVKKESEDPNYYQYNM 248
                  + D  R   +  E  G   V   P       L  +A  V  +   P     +M
Sbjct: 204 -------LEDGGRDSKALVELNG---VSLIPKGSRDCGLHGQAPKVPPQDLPPTATSSSM 253

Query: 249 QG-SHPSSTSNEVIEMELPMEDSTPLVPSEEPNEDPEAEVKIEGNTNSSSVTNS------ 301
               + ++  N  I        S PL PS+     P  E K  G  + S           
Sbjct: 254 ASFLYSTALPNHAIRELKQEAPSCPLAPSDLGLSRPMPEPKATGAQDFSDCCGQKPTGPG 313

Query: 302 ---AAGVEDLNIVQVTVPDNEKER----LSSIEKIKQLREQVNDLFSRKFGEAIGVDFPV 354
                 V     +  ++  ++ E+    +   E I  LRE V  LF+ ++ EA+G+D  V
Sbjct: 314 GPLIQNVHASKRILFSIVHDKSEKWDAFIKETEDINTLRECVQILFNSRYAEALGLDHMV 373

Query: 355 KVPYRKITFNPGCVVIDGMPPGVVFKAPGYLEISSMRRILEAAEFIKFTVIR 406
            VPYRKI  +P  V I G+P  + FK P    +  ++RILE    I F + R
Sbjct: 374 PVPYRKIACDPEAVEIVGIPDKIPFKRPCTYGVPKLKRILEERHSIHFIIKR 425



 Score =  136 bits (342), Expect = 1e-31
 Identities = 104/345 (30%), Positives = 154/345 (44%), Gaps = 94/345 (27%)

Query: 100 HSGETEILRKAVEDYFCFCYGKALGTTVMVPVPYEKMLRDQSAVVVQGLPEGVAFQHPEN 159
           H      LRK VE  F   Y KA+G +  V VPY K L     + V GLPEG++ + P  
Sbjct: 558 HGDVIRPLRKQVELLFNTRYAKAIGISEPVKVPYSKFLMHPEELFVVGLPEGISLRRPNC 617

Query: 160 YDLATLKWILENKAGISFIINRPFLGPESQLGGPGMVTDAERSIVSPSESCGPINVKTEP 219
           + +A L+ ILE    I F+I R           P ++T+  +                EP
Sbjct: 618 FGIAKLRKILEASNSIQFVIKR-----------PELLTEGVK----------------EP 650

Query: 220 MEDSGISLKAEAVSVKKESEDPNYYQYNMQGSHPSSTSNEVIEMELPMEDSTPLVPSEEP 279
           + DS                         QG+  S            +  S P +P E  
Sbjct: 651 IMDS-------------------------QGTASS------------LGFSPPALPPERD 673

Query: 280 NEDPEAEVKIEGNTNSSSVTNSAAGVEDLNIVQVTVPDNEKERLSSIEKIKQLREQVNDL 339
           + DP                     + D ++ +    +N   RLS I+    LREQV DL
Sbjct: 674 SGDP---------------------LVDESLKRQGFQENYDARLSRIDIANTLREQVQDL 712

Query: 340 FSRKFGEAIGVDFPVKVPYRKITFNPGCVVIDGMPPGVVFKAPGYLEISSMRRILEAAEF 399
           F++K+GEA+G+ +PV+VPY++I  NPG V+I+G+PPG+ F+ P      ++ RIL  A+ 
Sbjct: 713 FNKKYGEALGIKYPVQVPYKRIKSNPGSVIIEGLPPGIPFRKPCTFGSQNLERILAVADK 772

Query: 400 IKFTVIRPLPGL-------ELSNVGKRKI--DQEGRVFQEKWERA 435
           IKFTV RP  GL       + + +G++ I  +Q   +F EK+  A
Sbjct: 773 IKFTVTRPFQGLIPKPDEDDANRLGEKVILREQVKELFNEKYGEA 817



 Score =  118 bits (296), Expect = 2e-26
 Identities = 99/324 (30%), Positives = 143/324 (44%), Gaps = 57/324 (17%)

Query: 107 LRKAVEDYFCFCYGKALGTTVMVPVPYEKMLRDQSAVVVQGLPEGVAFQHPENYDLATLK 166
           LR+ V+  F   Y +ALG   MVPVPY K+  D  AV + G+P+ + F+ P  Y +  LK
Sbjct: 351 LRECVQILFNSRYAEALGLDHMVPVPYRKIACDPEAVEIVGIPDKIPFKRPCTYGVPKLK 410

Query: 167 WILENKAGISFIINRPF----------------LGPESQLGGPGMVTDAERSIVSPSESC 210
            ILE +  I FII R F                L P S    P   T AE S  +  +  
Sbjct: 411 RILEERHSIHFIIKRMFDERIFTGNKFTKDTTKLEPAS----PPEDTSAEVSRATVLDLA 466

Query: 211 GPINVKTEPM-EDSGISLKAEAVS---VKKESEDPNYYQYNMQGSHPSSTSNEVIEMELP 266
           G        M ED G     E      +K E ED +  Q  +    P+S           
Sbjct: 467 GNARSDKGSMSEDCGPGTSGELGGLRPIKIEPEDLDIIQVTVPDPSPTS----------- 515

Query: 267 MEDSTPLVPSEEPNEDPEAEVKIEGNTNSSSVTNSAAGVE---DLNIVQVTVPDNEKERL 323
            E+ T  +P   P+ED                  S  G+E   D  + +   P+      
Sbjct: 516 -EEMTDSMPGHLPSED------------------SGYGMEMLTDKGLSEDARPEERPVED 556

Query: 324 SSIEKIKQLREQVNDLFSRKFGEAIGVDFPVKVPYRKITFNPGCVVIDGMPPGVVFKAPG 383
           S  + I+ LR+QV  LF+ ++ +AIG+  PVKVPY K   +P  + + G+P G+  + P 
Sbjct: 557 SHGDVIRPLRKQVELLFNTRYAKAIGISEPVKVPYSKFLMHPEELFVVGLPEGISLRRPN 616

Query: 384 YLEISSMRRILEAAEFIKFTVIRP 407
              I+ +R+ILEA+  I+F + RP
Sbjct: 617 CFGIAKLRKILEASNSIQFVIKRP 640



 Score = 56.2 bits (134), Expect = 1e-07
 Identities = 33/79 (41%), Positives = 49/79 (62%), Gaps = 2/79 (2%)

Query: 102 GETEILRKAVEDYFCFCYGKALGTTVMVPVPYEKMLRDQ-SAVVVQGLPEGVAFQHPENY 160
           GE  ILR+ V++ F   YG+ALG    V VPY K++RD   AV V GLP+ + F++P  Y
Sbjct: 797 GEKVILREQVKELFNEKYGEALGLNRPVLVPY-KLIRDSPDAVEVTGLPDDIPFRNPNTY 855

Query: 161 DLATLKWILENKAGISFII 179
           D+  L+ IL+ +  +  +I
Sbjct: 856 DIHRLEKILKAREHVRMVI 874



 Score = 54.3 bits (129), Expect = 5e-07
 Identities = 25/77 (32%), Positives = 44/77 (57%)

Query: 332 LREQVNDLFSRKFGEAIGVDFPVKVPYRKITFNPGCVVIDGMPPGVVFKAPGYLEISSMR 391
           LR+ V ++F   + EA+G    V +PY ++   PG + + G+P G+ F+ P   +  ++ 
Sbjct: 128 LRKMVEEVFDVLYSEALGRASVVPLPYERLLREPGLLAVQGLPEGLAFRRPAEYDPKALM 187

Query: 392 RILEAAEFIKFTVIRPL 408
            ILE +  I+F + RPL
Sbjct: 188 AILEHSHRIRFKLKRPL 204


>gi|15011924 GTF2I repeat domain containing 1 isoform 2 [Homo
           sapiens]
          Length = 944

 Score =  181 bits (459), Expect = 3e-45
 Identities = 131/412 (31%), Positives = 189/412 (45%), Gaps = 43/412 (10%)

Query: 22  VVTFLVSALESMCKELAKSKAEVACIAVYETDVFVVGTERGCAFVNARTDFQKDFAKYCV 81
           ++T LVSAL+SMC  L+K  AEVAC+AV++   FVVGTE+G  F+NAR + Q DF ++C 
Sbjct: 30  IITSLVSALDSMCSALSKLNAEVACVAVHDESAFVVGTEKGRMFLNARKELQSDFLRFCR 89

Query: 82  AEGLCEVKPPCPVNGMQ-------------VHSGETEILRKAVEDYFCFCYGKALGTTVM 128
                + +   P    +              H  +  +LRK VE+ F   Y +ALG   +
Sbjct: 90  GPPWKDPEAEHPKKVQRGEGGGRSLPRSSLEHGSDVYLLRKMVEEVFDVLYSEALGRASV 149

Query: 129 VPVPYEKMLRDQSAVVVQGLPEGVAFQHPENYDLATLKWILENKAGISFIINRPFLGPES 188
           VP+PYE++LR+   + VQGLPEG+AF+ P  YD   L  ILE+   I F + RP      
Sbjct: 150 VPLPYERLLREPGLLAVQGLPEGLAFRRPAEYDPKALMAILEHSHRIRFKLKRP------ 203

Query: 189 QLGGPGMVTDAERSIVSPSESCGPINVKTEPMEDSGISLKAEAVSVKKESEDPNYYQYNM 248
                  + D  R   +  E  G   V   P       L  +A  V  +   P     +M
Sbjct: 204 -------LEDGGRDSKALVELNG---VSLIPKGSRDCGLHGQAPKVPPQDLPPTATSSSM 253

Query: 249 QG-SHPSSTSNEVIEMELPMEDSTPLVPSEEPNEDPEAEVKIEGNTNSSSVTNS------ 301
               + ++  N  I        S PL PS+     P  E K  G  + S           
Sbjct: 254 ASFLYSTALPNHAIRELKQEAPSCPLAPSDLGLSRPMPEPKATGAQDFSDCCGQKPTGPG 313

Query: 302 ---AAGVEDLNIVQVTVPDNEKER----LSSIEKIKQLREQVNDLFSRKFGEAIGVDFPV 354
                 V     +  ++  ++ E+    +   E I  LRE V  LF+ ++ EA+G+D  V
Sbjct: 314 GPLIQNVHASKRILFSIVHDKSEKWDAFIKETEDINTLRECVQILFNSRYAEALGLDHMV 373

Query: 355 KVPYRKITFNPGCVVIDGMPPGVVFKAPGYLEISSMRRILEAAEFIKFTVIR 406
            VPYRKI  +P  V I G+P  + FK P    +  ++RILE    I F + R
Sbjct: 374 PVPYRKIACDPEAVEIVGIPDKIPFKRPCTYGVPKLKRILEERHSIHFIIKR 425



 Score =  118 bits (296), Expect = 2e-26
 Identities = 99/324 (30%), Positives = 143/324 (44%), Gaps = 57/324 (17%)

Query: 107 LRKAVEDYFCFCYGKALGTTVMVPVPYEKMLRDQSAVVVQGLPEGVAFQHPENYDLATLK 166
           LR+ V+  F   Y +ALG   MVPVPY K+  D  AV + G+P+ + F+ P  Y +  LK
Sbjct: 351 LRECVQILFNSRYAEALGLDHMVPVPYRKIACDPEAVEIVGIPDKIPFKRPCTYGVPKLK 410

Query: 167 WILENKAGISFIINRPF----------------LGPESQLGGPGMVTDAERSIVSPSESC 210
            ILE +  I FII R F                L P S    P   T AE S  +  +  
Sbjct: 411 RILEERHSIHFIIKRMFDERIFTGNKFTKDTTKLEPAS----PPEDTSAEVSRATVLDLA 466

Query: 211 GPINVKTEPM-EDSGISLKAEAVS---VKKESEDPNYYQYNMQGSHPSSTSNEVIEMELP 266
           G        M ED G     E      +K E ED +  Q  +    P+S           
Sbjct: 467 GNARSDKGSMSEDCGPGTSGELGGLRPIKIEPEDLDIIQVTVPDPSPTS----------- 515

Query: 267 MEDSTPLVPSEEPNEDPEAEVKIEGNTNSSSVTNSAAGVE---DLNIVQVTVPDNEKERL 323
            E+ T  +P   P+ED                  S  G+E   D  + +   P+      
Sbjct: 516 -EEMTDSMPGHLPSED------------------SGYGMEMLTDKGLSEDARPEERPVED 556

Query: 324 SSIEKIKQLREQVNDLFSRKFGEAIGVDFPVKVPYRKITFNPGCVVIDGMPPGVVFKAPG 383
           S  + I+ LR+QV  LF+ ++ +AIG+  PVKVPY K   +P  + + G+P G+  + P 
Sbjct: 557 SHGDVIRPLRKQVELLFNTRYAKAIGISEPVKVPYSKFLMHPEELFVVGLPEGISLRRPN 616

Query: 384 YLEISSMRRILEAAEFIKFTVIRP 407
              I+ +R+ILEA+  I+F + RP
Sbjct: 617 CFGIAKLRKILEASNSIQFVIKRP 640



 Score =  111 bits (277), Expect = 4e-24
 Identities = 93/336 (27%), Positives = 148/336 (44%), Gaps = 36/336 (10%)

Query: 100 HSGETEILRKAVEDYFCFCYGKALGTTVMVPVPYEKMLRDQSAVVVQGLPEGVAFQHPEN 159
           H      LRK VE  F   Y KA+G +  V VPY K L     + V GLPEG++ + P  
Sbjct: 558 HGDVIRPLRKQVELLFNTRYAKAIGISEPVKVPYSKFLMHPEELFVVGLPEGISLRRPNC 617

Query: 160 YDLATLKWILENKAGISFIINRPFL-----------GPESQLGGPGMVTDAERSIVSPSE 208
           + +A L+ ILE    I F+I RP L             E   G P +    +R     + 
Sbjct: 618 FGIAKLRKILEASNSIQFVIKRPELLTEGVKEPIVDSQERDSGDPLVDESLKRQGFQENY 677

Query: 209 SC-----GPINVKTEPMEDSGISLKAEAVSVKKESEDPNYYQYNMQGSHPSSTSNEVIEM 263
                     N   E ++D       EA+ +K   + P    Y    S+P S   E +  
Sbjct: 678 DARLSRIDIANTLREQVQDLFNKKYGEALGIKYPVQVP----YKRIKSNPGSVIIEGLPP 733

Query: 264 ELPMEDSTPLVPSEEPNEDPEAEVKIEGNTNSSSVTNSAAGVEDLNIVQVTVPDNEKERL 323
            +P        P    +++ E  + +      + VT    G+         +P  +++  
Sbjct: 734 GIPFRK-----PCTFGSQNLERILAVADKIKFT-VTRPFQGL---------IPKPDEDDA 778

Query: 324 SSIEKIKQLREQVNDLFSRKFGEAIGVDFPVKVPYRKITFNPGCVVIDGMPPGVVFKAPG 383
           + + +   LREQV +LF+ K+GEA+G++ PV VPY+ I  +P  V + G+P  + F+ P 
Sbjct: 779 NRLGEKVILREQVKELFNEKYGEALGLNRPVLVPYKLIRDSPDAVEVTGLPDDIPFRNPN 838

Query: 384 YLEISSMRRILEAAEFIKFTVIRPL-PGLELSNVGK 418
             +I  + +IL+A E ++  +I  L P  E+ N  K
Sbjct: 839 TYDIHRLEKILKAREHVRMVIINQLQPFAEICNDAK 874



 Score =  106 bits (264), Expect = 1e-22
 Identities = 55/128 (42%), Positives = 82/128 (64%), Gaps = 9/128 (7%)

Query: 317 DNEKERLSSIEKIKQLREQVNDLFSRKFGEAIGVDFPVKVPYRKITFNPGCVVIDGMPPG 376
           +N   RLS I+    LREQV DLF++K+GEA+G+ +PV+VPY++I  NPG V+I+G+PPG
Sbjct: 675 ENYDARLSRIDIANTLREQVQDLFNKKYGEALGIKYPVQVPYKRIKSNPGSVIIEGLPPG 734

Query: 377 VVFKAPGYLEISSMRRILEAAEFIKFTVIRPLPGL-------ELSNVGKRKI--DQEGRV 427
           + F+ P      ++ RIL  A+ IKFTV RP  GL       + + +G++ I  +Q   +
Sbjct: 735 IPFRKPCTFGSQNLERILAVADKIKFTVTRPFQGLIPKPDEDDANRLGEKVILREQVKEL 794

Query: 428 FQEKWERA 435
           F EK+  A
Sbjct: 795 FNEKYGEA 802



 Score = 54.3 bits (129), Expect = 5e-07
 Identities = 25/77 (32%), Positives = 44/77 (57%)

Query: 332 LREQVNDLFSRKFGEAIGVDFPVKVPYRKITFNPGCVVIDGMPPGVVFKAPGYLEISSMR 391
           LR+ V ++F   + EA+G    V +PY ++   PG + + G+P G+ F+ P   +  ++ 
Sbjct: 128 LRKMVEEVFDVLYSEALGRASVVPLPYERLLREPGLLAVQGLPEGLAFRRPAEYDPKALM 187

Query: 392 RILEAAEFIKFTVIRPL 408
            ILE +  I+F + RPL
Sbjct: 188 AILEHSHRIRFKLKRPL 204


>gi|46195755 SCAN domain containing 3 [Homo sapiens]
          Length = 1325

 Score =  156 bits (395), Expect = 8e-38
 Identities = 151/593 (25%), Positives = 266/593 (44%), Gaps = 82/593 (13%)

Query: 415  NVGKRKIDQEGRV------FQEKWERAYF---FVEVQN----IPTCLICKQSMS--VSKE 459
            NV  R   +EG+       F  K++ +Y    FV V +     P C+IC   ++    K 
Sbjct: 714  NVNNRSYPEEGKTKRVHASFTRKYDPSYIEFGFVAVIDGEVLKPQCIICGDVLANEAMKP 773

Query: 460  YNLRRHYQTNH---SKHYDQYMERMRDEKLHELKK----------GLR---KYLLGLSDT 503
              L+RH  + H   S    ++ ER   E   + K+           LR   K  L ++ +
Sbjct: 774  SKLKRHLYSKHKEISSQPKEFFERKSSELKSQPKQVFNVSHINISALRASYKVALPVAKS 833

Query: 504  ECPEQ----------KQVFAH---PSPTQKSPVQP---------VEDLAGNLWEKLREKI 541
            + P            K+V       S  +K    P         +++LA ++ ++L E+I
Sbjct: 834  KTPYTIAETLVKDCIKEVCLEMLGESAAKKVAQVPLSNDTIARRIQELANDMEDQLIEQI 893

Query: 542  RSFVAYSIAIDEITDINNTTQLAIFIRGVDENFDVSEELLDTVPMTGTKSGNEIFSRVEK 601
            +    +S+ +DE  DI N   L +++R  + + D+ EE   +  +    + +E++  V+ 
Sbjct: 894  KLAKYFSLQLDECRDIANMIILLVYVR-FEHDDDIKEEFFFSASLPTNTTSSELYEAVKN 952

Query: 602  SLKKFC-IDWSKLVSVASTGTPAMVDANNGLVTKLKSRVATFCKGAELKSICCIIHPESL 660
             +   C +++   V V S G  +M   ++ +VT++K          E K+  C IH ESL
Sbjct: 953  YIVNKCGLEFKFCVGVCSDGAASMTGKHSEVVTQIKELAP------ECKTTHCFIHRESL 1006

Query: 661  CAQKL--KMDHVMDVVVKSVNWICSRGLNHSEFTTLLYELDSQYGSLLYYTEIKWLSRGL 718
              +K+  +++ V++ +VK VN+I S  LN   F+ L   +++ +  LL + EI+WLSRG 
Sbjct: 1007 AMKKISAELNSVLNDIVKIVNYIKSNSLNSRLFSLLCDNMEADHKQLLLHAEIRWLSRGK 1066

Query: 719  VLKRFFESLEEIDSFMSSRGKPLPQL-SSIDWIRDLAFLVDMTMHLNALNISLQGHSQIV 777
            VL R FE   E+  F+  +     QL   ++W   LA+L D+    N LN S+QG +   
Sbjct: 1067 VLSRMFEIRNELLVFLQGKKPMWSQLFKDVNWTARLAYLSDIFSIFNDLNASMQGKNATY 1126

Query: 778  TQMYDLIRAFLAKLCLWETHLTRNNLAHFPTLKLASRNESDGLNYIPKIAELKTEFQKRL 837
              M D +     KL  W+  ++ +    F  L        + L+    IA L+    + L
Sbjct: 1127 FSMADKVEGQKQKLEAWKNRISTDCYDMFHNLTTIINEVGNDLD----IAHLRKVISEHL 1182

Query: 838  SD----FKLYESEL-------TLFSSPFSTKIDSVH--EELQMEVIDLQCNTVLKTKYDK 884
            ++    F+ Y               +PF +  D+++    LQ +++ L  +  LK  ++ 
Sbjct: 1183 TNLLECFEFYFPSKEDPRIGNLWIQNPFLSSKDNLNLTVTLQDKLLKLATDEGLKISFEN 1242

Query: 885  -VGIPEFYKYLWGSYPKYKHHCAKILSMFGSTYICEQLFSIMKLSKTKYCSQL 936
               +P F+      YP+      K+L +F STY+CE  FS + + KTK+ + L
Sbjct: 1243 TASLPSFWIKAKNDYPELAEIALKLLLLFPSTYLCETGFSTLSVIKTKHRNSL 1295


>gi|115511046 zinc finger protein 258 [Homo sapiens]
          Length = 1325

 Score =  156 bits (394), Expect = 1e-37
 Identities = 136/545 (24%), Positives = 243/545 (44%), Gaps = 71/545 (13%)

Query: 445  PTCLICKQSMSVS--KEYNLRRHYQTNHSKHYDQYMERMRDEKLHE--LKKGLRKYLLGL 500
            P C+IC + +S    K  NL  H +T HS+  ++ ++    + L        L+K LL  
Sbjct: 766  PQCVICGEILSSENMKPANLSHHLKTKHSELENKPVDFFEQKSLEMECQNSSLKKCLL-- 823

Query: 501  SDTECPEQKQVFAHPSPTQKSP-------VQP---------------------------- 525
             +    +   + A  +   K P       ++P                            
Sbjct: 824  VEKSLVKASYLIAFQTAASKKPFSIAEELIKPYLVEMCSEVLGSSAGDKMKTIPLSNVTI 883

Query: 526  ---VEDLAGNLWEKLREKIRSFVAYSIAIDEITDINNTTQLAIFIRGVDENF-DVSEELL 581
               +++L+ ++ ++L +K+R    +++ IDE ++I+N T L  +IR +D +  DV EELL
Sbjct: 884  QHRIDELSADIEDQLIQKVRESKWFALQIDESSEISNITLLLCYIRFIDYDCRDVKEELL 943

Query: 582  DTVPMTGTKSGNEIFSRVEKSLKKFCIDWSKLVSVASTGTPAMVDANNGLVTKLKS---R 638
              + M    +G EIF  + K +    ++W   V + + G  +M    +GL  K++     
Sbjct: 944  FCIEMPTQITGFEIFELINKYIDSKSLNWKHCVGLCTDGAASMTGRYSGLKAKIQEVAMN 1003

Query: 639  VATFCKGAELKSICCIIHPESLCAQKLK--MDHVMDVVVKSVNWICSRGLNHSEFTTLLY 696
             A F          C IH E L A+KL   +  ++    + +++I S  LN    T L  
Sbjct: 1004 TAAFTH--------CFIHRERLVAEKLSPCLHKILLQSAQILSFIKSNALNSRMLTILCE 1055

Query: 697  ELDSQYGSLLYYTEIKWLSRGLVLKRFFESLEEIDSFMSSRGKPLPQ-LSSIDWIRDLAF 755
            E+ S++ SL  + E++W+SRG +LKR FE   EI+ F+S +   L +     +W+  LA+
Sbjct: 1056 EMGSEHVSLPLHAEVRWISRGRMLKRLFELRHEIEIFLSQKHSDLAKYFHDEEWVGKLAY 1115

Query: 756  LVDMTMHLNALNISLQGHSQIVTQMYDLIRAFLAKLCLWETHLTRNNLAHFPTLKLASRN 815
            L D+   +N LN+SLQG       + + I  F  KL +W      N+   FP+   +  +
Sbjct: 1116 LSDIFSLINELNLSLQGTLTTFFNLCNKIDVFKRKLKMWLKRTQENDYDMFPS--FSEFS 1173

Query: 816  ESDGLNYIPKIAELKTEFQKRLS---------DFKLYESELTLFSSPFSTKIDSVHEELQ 866
             S GLN +  I  +  E  + LS         +  L    L +     + + +++ +  +
Sbjct: 1174 NSSGLN-MTDITRIIFEHLEGLSQVFSDCFPPEQDLRSGNLWIIHPFMNHQNNNLTDFEE 1232

Query: 867  MEVIDLQCNTVLKTKYDKVGIPEFYKYLWGSYPKYKHHCAKILSMFGSTYICEQLFSIMK 926
             ++ +L  +  L+  +  V + +F+     SYP+      K L  F + Y+C+  FS + 
Sbjct: 1233 EKLTELSSDLGLQALFKSVSVTQFWINAKTSYPELHERAMKFLLPFSTVYLCDAAFSALT 1292

Query: 927  LSKTK 931
             SK K
Sbjct: 1293 ESKQK 1297


>gi|219521826 zinc finger, BED-type containing 5 [Homo sapiens]
          Length = 693

 Score =  155 bits (393), Expect = 1e-37
 Identities = 115/420 (27%), Positives = 204/420 (48%), Gaps = 18/420 (4%)

Query: 526 VEDLAGNLWEKLREKIRSFVAYSIAIDEITDINNTTQLAIFIRGVDENFDVSEELLDTVP 585
           ++DLA ++ E+L  +++    +S+ +DE  D++    L +F+R    N  + E+LL    
Sbjct: 252 IKDLAADIEEELVCRLKICDGFSLQLDESADVSGLAVLLVFVR-YRFNKSIEEDLLLCES 310

Query: 586 MTGTKSGNEIFSRVEKSLKKFCIDWSKLVSVASTGTPAMVDANNGLVTKLKSRVATFCKG 645
           +    +G EIF+ +   ++K  I+W K V V S  + A VD        L   VA     
Sbjct: 311 LQSNATGEEIFNCINSFMQKHEIEWEKCVDVCSDASRA-VDGKIAEAVTLIKYVAP---- 365

Query: 646 AELKSICCIIHPESLCAQKL--KMDHVMDVVVKSVNWICSRGLNHSEFTTLLYELDSQYG 703
            E  S  C+++  +L  + +   + +V+D  V+ +N+I +R         L  E+ +Q+ 
Sbjct: 366 -ESTSSHCLLYRHALAVKIMPTSLKNVLDQAVQIINYIKARPHQSRLLKILCEEMGAQHT 424

Query: 704 SLLYYTEIKWLSRGLVLKRFFESLEEIDSFMSSRGKPLPQLSSIDWIRDLAFLVDMTMHL 763
           +LL  TE++WLSRG VL R FE   E+  FM S  +    L++  W+  LA+L D+   L
Sbjct: 425 ALLLNTEVRWLSRGKVLVRLFELRRELLVFMDSAFRLSDCLTNSSWLLRLAYLADIFTKL 484

Query: 764 NALNISLQGHSQIVTQMYDLIRAFLAKLCLWETHLTRNNLAHFPTL-----KLASRNESD 818
           N +N+S+QG +  V  ++D + + L KL  W + +   N   FPTL     ++ S  + D
Sbjct: 485 NEVNLSMQGKNVTVFTVFDKMSSLLRKLEFWASSVEEENFDCFPTLSDFLTEINSTVDKD 544

Query: 819 GLNYIPKIAELKTEFQKRLSDFKLYESELTLFSSPFSTKID--SVHEELQMEVIDLQCNT 876
             + I  +  L+      L  F +         +PF+  +   S+       +IDL  ++
Sbjct: 545 ICSAI--VQHLRGLRATLLKYFPVTNDNNAWVRNPFTVTVKPASLVARDYESLIDLTSDS 602

Query: 877 VLKTKYDKVGIPEFYKYLWGSYPKYKHHCAKILSMFGSTYICEQLFSIMKLSKTKYCSQL 936
            +K  + ++ + +F+  L   YP       ++L  F + ++CE  FS    +KTKY  +L
Sbjct: 603 QVKQNFSELSLNDFWSSLIQEYPSIARRAVRVLLPFATMHLCETGFSYYAATKTKYRKRL 662


>gi|49574210 zinc finger, BED-type containing 5 [Homo sapiens]
          Length = 693

 Score =  155 bits (393), Expect = 1e-37
 Identities = 115/420 (27%), Positives = 204/420 (48%), Gaps = 18/420 (4%)

Query: 526 VEDLAGNLWEKLREKIRSFVAYSIAIDEITDINNTTQLAIFIRGVDENFDVSEELLDTVP 585
           ++DLA ++ E+L  +++    +S+ +DE  D++    L +F+R    N  + E+LL    
Sbjct: 252 IKDLAADIEEELVCRLKICDGFSLQLDESADVSGLAVLLVFVR-YRFNKSIEEDLLLCES 310

Query: 586 MTGTKSGNEIFSRVEKSLKKFCIDWSKLVSVASTGTPAMVDANNGLVTKLKSRVATFCKG 645
           +    +G EIF+ +   ++K  I+W K V V S  + A VD        L   VA     
Sbjct: 311 LQSNATGEEIFNCINSFMQKHEIEWEKCVDVCSDASRA-VDGKIAEAVTLIKYVAP---- 365

Query: 646 AELKSICCIIHPESLCAQKL--KMDHVMDVVVKSVNWICSRGLNHSEFTTLLYELDSQYG 703
            E  S  C+++  +L  + +   + +V+D  V+ +N+I +R         L  E+ +Q+ 
Sbjct: 366 -ESTSSHCLLYRHALAVKIMPTSLKNVLDQAVQIINYIKARPHQSRLLKILCEEMGAQHT 424

Query: 704 SLLYYTEIKWLSRGLVLKRFFESLEEIDSFMSSRGKPLPQLSSIDWIRDLAFLVDMTMHL 763
           +LL  TE++WLSRG VL R FE   E+  FM S  +    L++  W+  LA+L D+   L
Sbjct: 425 ALLLNTEVRWLSRGKVLVRLFELRRELLVFMDSAFRLSDCLTNSSWLLRLAYLADIFTKL 484

Query: 764 NALNISLQGHSQIVTQMYDLIRAFLAKLCLWETHLTRNNLAHFPTL-----KLASRNESD 818
           N +N+S+QG +  V  ++D + + L KL  W + +   N   FPTL     ++ S  + D
Sbjct: 485 NEVNLSMQGKNVTVFTVFDKMSSLLRKLEFWASSVEEENFDCFPTLSDFLTEINSTVDKD 544

Query: 819 GLNYIPKIAELKTEFQKRLSDFKLYESELTLFSSPFSTKID--SVHEELQMEVIDLQCNT 876
             + I  +  L+      L  F +         +PF+  +   S+       +IDL  ++
Sbjct: 545 ICSAI--VQHLRGLRATLLKYFPVTNDNNAWVRNPFTVTVKPASLVARDYESLIDLTSDS 602

Query: 877 VLKTKYDKVGIPEFYKYLWGSYPKYKHHCAKILSMFGSTYICEQLFSIMKLSKTKYCSQL 936
            +K  + ++ + +F+  L   YP       ++L  F + ++CE  FS    +KTKY  +L
Sbjct: 603 QVKQNFSELSLNDFWSSLIQEYPSIARRAVRVLLPFATMHLCETGFSYYAATKTKYRKRL 662


>gi|239746033 PREDICTED: hypothetical protein XP_002344174 [Homo
           sapiens]
          Length = 145

 Score =  149 bits (375), Expect = 2e-35
 Identities = 92/182 (50%), Positives = 105/182 (57%), Gaps = 38/182 (20%)

Query: 1   MAQVAVSTLPVEEESSSETRMVVTFLVSALESM-CKELAKSKAEVACIAVYETDVFVVGT 59
           MAQV VSTL +E+E S E+RMVVTFL+SALES  C  +   K E  C  +Y   V+  G 
Sbjct: 1   MAQVLVSTLSIEDEDSYESRMVVTFLMSALESTDCFRVWILKQE--CTLIYHKKVYNPGE 58

Query: 60  ERGCAFVNARTDFQKDFAKYCVAEGLCEVKPPCPVNGMQVHSGETEILRKAVEDYFCFCY 119
              C                            C  NG           +K VEDYFCFC 
Sbjct: 59  SDECR---------------------------CCRNG--------NTRKKTVEDYFCFCC 83

Query: 120 GKALGTTVMVPVPYEKMLRDQSAVVVQGLPEGVAFQHPENYDLATLKWILENKAGISFII 179
            KAL     VPVPYEKML+DQSA++VQGLPEGVAF+HPENYDLATL+WILE  AGISFII
Sbjct: 84  RKALQKPTEVPVPYEKMLQDQSALIVQGLPEGVAFKHPENYDLATLEWILEYTAGISFII 143

Query: 180 NR 181
            R
Sbjct: 144 KR 145



 Score = 41.6 bits (96), Expect = 0.004
 Identities = 22/74 (29%), Positives = 38/74 (51%)

Query: 333 REQVNDLFSRKFGEAIGVDFPVKVPYRKITFNPGCVVIDGMPPGVVFKAPGYLEISSMRR 392
           ++ V D F     +A+     V VPY K+  +   +++ G+P GV FK P   +++++  
Sbjct: 72  KKTVEDYFCFCCRKALQKPTEVPVPYEKMLQDQSALIVQGLPEGVAFKHPENYDLATLEW 131

Query: 393 ILEAAEFIKFTVIR 406
           ILE    I F + R
Sbjct: 132 ILEYTAGISFIIKR 145


>gi|223633919 hypothetical protein LOC285550 [Homo sapiens]
          Length = 657

 Score =  146 bits (369), Expect = 8e-35
 Identities = 137/549 (24%), Positives = 248/549 (45%), Gaps = 70/549 (12%)

Query: 445 PTCLICKQSMSVS--KEYNLRRHYQTNHSKHYDQYME----RMRDEKLHEL--------- 489
           P C+IC   ++    K   L+RH +T H++  D+ +E    + +D KL            
Sbjct: 84  PQCVICNNILANESLKPSKLKRHLETQHAELIDKPLEYFQRKKKDIKLSTQFLSCSTAVS 143

Query: 490 -KKGLRKYLLG-------LSDTE--------CPEQKQVFAHPSPTQKSPVQPVED----- 528
            K  L  YL+        +++T         C +  +         K    P ++     
Sbjct: 144 EKALLSSYLVAYRVAKEKIANTAAEKIILPACLDMVRTIFDDKSADKLKTIPNDNTVSLR 203

Query: 529 ---LAGNLWEKLREKIRSFVAYSIAIDEITDINNTTQLAIFIRGVDENFDVSEELLDTVP 585
              +A +L   L  +++S + ++I +DE TDI + T L +++R   ++ D  E+ L  + 
Sbjct: 204 ICTIAEHLETMLITRLQSGIDFAIQLDESTDIGSCTTLLVYVRYAWQD-DFLEDFLCFLN 262

Query: 586 MTGTKSGNEIFSRVEKSLK-KFCIDWSKLVSVASTGTPAMVDANNGLVTKLKSRVATFCK 644
           +T   SG +IF+ +E+ +  ++ ++W     + S GT  M   ++ ++ KL   +     
Sbjct: 263 LTSHLSGLDIFTELERRIVGQYKLNWKNCKGITSDGTATMTGKHSRVIKKL---LEVTNN 319

Query: 645 GAELKSICCIIHPESLCAQKLKMD--HVMDVVVKSVNWICSRGLNHSEFTTLLYELDSQY 702
           GA      C IH E L ++++  +   V+   VK VN+I    LN     T   E+ + +
Sbjct: 320 GAVWNH--CFIHREGLASREIPQNLMEVLKNAVKVVNFIKGSSLNSRLLETFCSEIGTNH 377

Query: 703 GSLLYYTEIKWLSRGLVLKRFFESLEEIDSFMSSRGKPLPQLSSID-WIRDLAFLVDMTM 761
             LLY+T+I+WLS+G +L R +E   EI  F+  +   L  +   D W+  LA+L D+  
Sbjct: 378 THLLYHTKIRWLSQGKILSRVYELRNEIHFFLIEKKSHLASIFEDDTWVTKLAYLTDIFS 437

Query: 762 HLNALNISLQGHSQIVTQMYDLIRAFLAKLCLWETHLTRNNLAHFPTLKLASRNESDGLN 821
            LN L++ LQG +  V Q  + I+ F   L LW+  L  N  +++   +     E + +N
Sbjct: 438 ILNELSLKLQGKNSDVFQHVERIQGFRKTLLLWQVRLKSNRPSYYMFPRFLQHIEENIIN 497

Query: 822 YIPKIAELKTEFQKRLSDF----------KLYES--ELTLFSSPFS-------TKIDSVH 862
               + E+K E    L+            + +E+  E +    PF+        +++ V 
Sbjct: 498 E-NILKEIKLEILLHLTSLSQTFNHFFPEEKFETLRENSWVKDPFAFRHPESIIELNLVP 556

Query: 863 EELQMEVIDLQCNTVLKTKYDKVGIPEFYKYLWGSYPKYKHHCAKILSMFGSTYICEQLF 922
           EE + E++ L  +  LK  Y+ + +  F+  +   +P        +L  F +T +CE  F
Sbjct: 557 EE-ENELLQLSSSYTLKNDYETLSLSAFWMKVKEDFPLLSRKSVLLLLPFTTTSLCELGF 615

Query: 923 SIMKLSKTK 931
           SI+   KTK
Sbjct: 616 SILTQLKTK 624


>gi|28916698 transposon-derived Buster3 transposase-like [Homo
           sapiens]
          Length = 594

 Score =  145 bits (367), Expect = 1e-34
 Identities = 108/425 (25%), Positives = 206/425 (48%), Gaps = 20/425 (4%)

Query: 526 VEDLAGNLWEKLREKIR-SFVAYSIAIDEITDINNTTQLAIFIRGVDENFDVSEELLDTV 584
           +++++ ++ +++ E I+ S +   I + E TD+++ +QL  F+R + E  ++ EE L   
Sbjct: 150 IDEMSQDILQQVLEDIKASPLKVGIQLAETTDMDDCSQLMAFVRYIKER-EIVEEFLFCE 208

Query: 585 PMTGTKSGNEIFSRVEKSLKKFCIDWSKLVSVASTGTPAMVDANNGLVTKLKSRVATFCK 644
           P+  +  G ++F+       K  I      SV + G  +M+  N+  V  +K  +     
Sbjct: 209 PLQLSMKGIDVFNLFRDFFLKHKIALDVCGSVCTDGASSMLGENSEFVAYVKKEIP---- 264

Query: 645 GAELKSICCIIHPESLCAQKL--KMDHVMDVVVKSVNWICSRGLNHSEFTTLLYELDSQY 702
              +    C+++P +L  + L  K+   +  VV+ +N+I  R  NH  F     E+  +Y
Sbjct: 265 --HIVVTHCLLNPHALVIKTLPTKLRDALFTVVRVINFIKGRAPNHRLFQAFFEEIGIEY 322

Query: 703 GSLLYYTEIKWLSRGLVLKRFFESLEEIDSFMSSRGKPLPQ-LSSIDWIRDLAFLVDMTM 761
             LL++TE++WLSRG +L   FE  EEI+ F+  +   L     + ++   LA+L D+  
Sbjct: 323 SVLLFHTEMRWLSRGQILTHIFEMYEEINQFLHHKSSNLVDGFENKEFKIHLAYLADLFK 382

Query: 762 HLNALNISLQGHSQIVTQMYDLIRAFLAKLCLWETHLTRNNLAHFPTLKLASRNESDGLN 821
           HLN L+ S+Q          + + AF+ K   W+  + + N  +FP L+    ++++G+ 
Sbjct: 383 HLNELSASMQRTGMNTVSAREKLSAFVRKFPFWQKRIEKRNFTNFPFLEEIIVSDNEGIF 442

Query: 822 YIPKIA----ELKTEFQKRLSDFKLYESELTLFSSPFSTKIDSVHEELQM--EVIDLQCN 875
              +I     +L   F    S   L E+   +   PF   ID V +   M  ++ +L+ +
Sbjct: 443 IAAEITLHLQQLSNFFHGYFSIGDLNEASKWIL-DPFLFNIDFVDDSYLMKNDLAELRAS 501

Query: 876 TVLKTKYDKVGIPEFYKYLWGSYPKYKHHCAKILSMFGSTYICEQLFSIMKLSKTK--YC 933
             +  +++ + + +F+   + ++P       +IL  F +TY+CE  FS +   KTK   C
Sbjct: 502 GQILMEFETMKLEDFWCAQFTAFPNLAKTALEILMPFATTYLCELGFSSLLHFKTKSRSC 561

Query: 934 SQLKD 938
             L D
Sbjct: 562 FNLSD 566


>gi|21495178 hypothetical protein LOC221786 [Homo sapiens]
          Length = 573

 Score =  135 bits (339), Expect = 2e-31
 Identities = 111/434 (25%), Positives = 202/434 (46%), Gaps = 31/434 (7%)

Query: 529 LAGNLWEKLREKIRSFVAYSIAIDEITDINNTTQLAIFIRGVDENFDVSEELLDTVPMTG 588
           +A +L   L  +++S + ++I +DE TDI +   L +++R V ++ D  E+LL  + +  
Sbjct: 122 IAKHLEAMLITRLQSGIDFAIQLDESTDIASCPTLLVYVRYVWQD-DFVEDLLCCLNLNS 180

Query: 589 TKSGNEIFSRVEKSLK-KFCIDWSKLVSVASTGTPAMVDANNGLVTKLKSRVATFCKGAE 647
             +G ++F+ +E  L  ++ ++W     ++S GT  M   ++ L  KL            
Sbjct: 181 HITGLDLFTELENCLLGQYKLNWKHCKGISSDGTANMTGKHSRLTEKLLEATHNNAVWNH 240

Query: 648 LKSICCIIHPESLCAQKLKMDHVMDVV---VKSVNWICSRGLNHSEFTTLLYELDSQYGS 704
                C IH E+L ++++    +MDV+   VK+VN+I    LN         E+   +  
Sbjct: 241 -----CFIHREALVSKEISPS-LMDVLKNAVKTVNFIKGSSLNSRLLEIFCSEIGVNHTH 294

Query: 705 LLYYTEIKWLSRGLVLKRFFESLEEIDSFMSSRGKPLPQLSSID-WIRDLAFLVDMTMHL 763
           LL++TE++WLS+G VL R +E   EI  F+  +   L  +   D W+  LA+L D+   L
Sbjct: 295 LLFHTEVRWLSQGKVLSRVYELRNEIYIFLVEKQSHLANIFEDDIWVTKLAYLSDIFGIL 354

Query: 764 NALNISLQGHSQIVTQMYDLIRAFLAKLCLWETHLTRNNLAHFPTLKLASRNESDGLNYI 823
           N L++ +QG +  + Q  + I  F   L LW+  L  N  +++    L    E + +N  
Sbjct: 355 NELSLKMQGKNNDIFQYLEHILGFQKTLLLWQARLKSNRPSYYMFPTLLQHIEENIINE- 413

Query: 824 PKIAELKTEFQKRLSDF------------------KLYESELTLFSSPFSTKIDSVHEEL 865
             + E+K E    L+                     ++  +   F +P S    ++  E 
Sbjct: 414 DCLKEIKLEILLHLTSLSQTFNYYFPEEKFESLKENIWMKDPFAFQNPESIIELNLEPEE 473

Query: 866 QMEVIDLQCNTVLKTKYDKVGIPEFYKYLWGSYPKYKHHCAKILSMFGSTYICEQLFSIM 925
           + E++ L  +  LK  Y  + +  F+  +   +P        +L  F +TY+CE  FSI+
Sbjct: 474 ENELLQLSSSFTLKNYYKILSLSAFWIKIKDDFPLLSRKSILLLLPFTTTYLCELGFSIL 533

Query: 926 KLSKTKYCSQLKDS 939
              KTK  ++L  +
Sbjct: 534 TRLKTKKRNRLNSA 547


>gi|239757552 PREDICTED: similar to hCG2006635, partial [Homo
           sapiens]
          Length = 304

 Score =  118 bits (296), Expect = 2e-26
 Identities = 56/72 (77%), Positives = 62/72 (86%)

Query: 108 RKAVEDYFCFCYGKALGTTVMVPVPYEKMLRDQSAVVVQGLPEGVAFQHPENYDLATLKW 167
           +K VEDYFCFC  KAL     VPVPYEKML+DQSA++VQGLPEGVAF+HPENYDLATL+W
Sbjct: 21  KKTVEDYFCFCCRKALQKPTEVPVPYEKMLQDQSALIVQGLPEGVAFKHPENYDLATLEW 80

Query: 168 ILENKAGISFII 179
           ILE  AGISFII
Sbjct: 81  ILEYTAGISFII 92



 Score = 40.8 bits (94), Expect = 0.006
 Identities = 21/72 (29%), Positives = 37/72 (51%)

Query: 333 REQVNDLFSRKFGEAIGVDFPVKVPYRKITFNPGCVVIDGMPPGVVFKAPGYLEISSMRR 392
           ++ V D F     +A+     V VPY K+  +   +++ G+P GV FK P   +++++  
Sbjct: 21  KKTVEDYFCFCCRKALQKPTEVPVPYEKMLQDQSALIVQGLPEGVAFKHPENYDLATLEW 80

Query: 393 ILEAAEFIKFTV 404
           ILE    I F +
Sbjct: 81  ILEYTAGISFII 92


>gi|239752592 PREDICTED: hypothetical protein XP_002348308, partial
           [Homo sapiens]
          Length = 94

 Score =  118 bits (295), Expect = 3e-26
 Identities = 56/74 (75%), Positives = 62/74 (83%)

Query: 108 RKAVEDYFCFCYGKALGTTVMVPVPYEKMLRDQSAVVVQGLPEGVAFQHPENYDLATLKW 167
           +K VEDYFCFC  K L     VPVPYEKML+DQSA++VQGLPEGVAF+HPENYDLATL+W
Sbjct: 21  KKTVEDYFCFCCLKTLQKPTEVPVPYEKMLQDQSALIVQGLPEGVAFKHPENYDLATLEW 80

Query: 168 ILENKAGISFIINR 181
           ILE  AGISFII R
Sbjct: 81  ILEYTAGISFIIKR 94



 Score = 39.7 bits (91), Expect = 0.013
 Identities = 18/53 (33%), Positives = 30/53 (56%)

Query: 354 VKVPYRKITFNPGCVVIDGMPPGVVFKAPGYLEISSMRRILEAAEFIKFTVIR 406
           V VPY K+  +   +++ G+P GV FK P   +++++  ILE    I F + R
Sbjct: 42  VPVPYEKMLQDQSALIVQGLPEGVAFKHPENYDLATLEWILEYTAGISFIIKR 94


>gi|239754606 PREDICTED: similar to hCG1983816 [Homo sapiens]
          Length = 298

 Score = 87.8 bits (216), Expect = 4e-17
 Identities = 48/134 (35%), Positives = 80/134 (59%), Gaps = 10/134 (7%)

Query: 317 DNEKERLSSIEKIKQLREQVNDLFSRKFGEAIGVDFPVKVPYRKITFNPGCVVIDGMPPG 376
           +N   RL  I+    LREQV +LF++ +GEA+G+ +PV+VPY+ I  NPG ++I+ +PPG
Sbjct: 95  ENYDARLLRIDIANTLREQVQELFNKTYGEALGIKYPVQVPYKWIKSNPGSMIIEELPPG 154

Query: 377 VVFKAPGYLEISSMRRILEAAEFIKFTVIRPLPGL-------ELSNVGKRKI-DQEGRVF 428
           ++F+ P      ++ RIL  A  I FTV RP  GL       + + +G+  + +Q   +F
Sbjct: 155 ILFRKP--FGSQNLERILAMANKITFTVTRPFQGLIRKPDEDDTNRLGEVILQEQVKELF 212

Query: 429 QEKWERAYFFVEVQ 442
            EK+ +  + ++ Q
Sbjct: 213 NEKYSQCLWLLQQQ 226



 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 27/79 (34%), Positives = 45/79 (56%), Gaps = 2/79 (2%)

Query: 107 LRKAVEDYFCFCYGKALGTTVMVPVPYEKMLRDQSAVVVQGLPEGVAFQHPENYDLATLK 166
           LR+ V++ F   YG+ALG    V VPY+ +  +  +++++ LP G+ F+ P  +    L+
Sbjct: 110 LREQVQELFNKTYGEALGIKYPVQVPYKWIKSNPGSMIIEELPPGILFRKP--FGSQNLE 167

Query: 167 WILENKAGISFIINRPFLG 185
            IL     I+F + RPF G
Sbjct: 168 RILAMANKITFTVTRPFQG 186



 Score = 37.7 bits (86), Expect = 0.051
 Identities = 32/99 (32%), Positives = 45/99 (45%), Gaps = 9/99 (9%)

Query: 145 VQGLPEGVAFQHPENYDLATLKWILENKAGISFIINRPFLGPESQLGGPGMVTDAERSIV 204
           V GLPEG++ + P  + +A L  ILE    I F+I RP L  E   G    + D++    
Sbjct: 8   VVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRPKLLTE---GVKEPIVDSQ---- 60

Query: 205 SPSESCGPINVKTEPMEDSGISLKAEAVSVKKESEDPNY 243
             + S G       P  DS   L  E  S+K++    NY
Sbjct: 61  GTASSLGFSPPALPPERDSRDPLVGE--SLKRQGFQENY 97



 Score = 32.3 bits (72), Expect = 2.2
 Identities = 14/44 (31%), Positives = 26/44 (59%)

Query: 364 NPGCVVIDGMPPGVVFKAPGYLEISSMRRILEAAEFIKFTVIRP 407
           +P  + + G+P G+  + P    I+ + +ILEA+  I+F + RP
Sbjct: 2   HPEELFVVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRP 45


>gi|239749152 PREDICTED: similar to hCG1983816 [Homo sapiens]
          Length = 265

 Score = 87.8 bits (216), Expect = 4e-17
 Identities = 48/134 (35%), Positives = 80/134 (59%), Gaps = 10/134 (7%)

Query: 317 DNEKERLSSIEKIKQLREQVNDLFSRKFGEAIGVDFPVKVPYRKITFNPGCVVIDGMPPG 376
           +N   RL  I+    LREQV +LF++ +GEA+G+ +PV+VPY+ I  NPG ++I+ +PPG
Sbjct: 95  ENYDARLLRIDIANTLREQVQELFNKTYGEALGIKYPVQVPYKWIKSNPGSMIIEELPPG 154

Query: 377 VVFKAPGYLEISSMRRILEAAEFIKFTVIRPLPGL-------ELSNVGKRKI-DQEGRVF 428
           ++F+ P      ++ RIL  A  I FTV RP  GL       + + +G+  + +Q   +F
Sbjct: 155 ILFRKP--FGSQNLERILAMANKITFTVTRPFQGLIRKPDEDDTNRLGEVILQEQVKELF 212

Query: 429 QEKWERAYFFVEVQ 442
            EK+ +  + ++ Q
Sbjct: 213 NEKYSQCLWLLQQQ 226



 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 27/79 (34%), Positives = 45/79 (56%), Gaps = 2/79 (2%)

Query: 107 LRKAVEDYFCFCYGKALGTTVMVPVPYEKMLRDQSAVVVQGLPEGVAFQHPENYDLATLK 166
           LR+ V++ F   YG+ALG    V VPY+ +  +  +++++ LP G+ F+ P  +    L+
Sbjct: 110 LREQVQELFNKTYGEALGIKYPVQVPYKWIKSNPGSMIIEELPPGILFRKP--FGSQNLE 167

Query: 167 WILENKAGISFIINRPFLG 185
            IL     I+F + RPF G
Sbjct: 168 RILAMANKITFTVTRPFQG 186



 Score = 37.7 bits (86), Expect = 0.051
 Identities = 32/99 (32%), Positives = 45/99 (45%), Gaps = 9/99 (9%)

Query: 145 VQGLPEGVAFQHPENYDLATLKWILENKAGISFIINRPFLGPESQLGGPGMVTDAERSIV 204
           V GLPEG++ + P  + +A L  ILE    I F+I RP L  E   G    + D++    
Sbjct: 8   VVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRPKLLTE---GVKEPIVDSQ---- 60

Query: 205 SPSESCGPINVKTEPMEDSGISLKAEAVSVKKESEDPNY 243
             + S G       P  DS   L  E  S+K++    NY
Sbjct: 61  GTASSLGFSPPALPPERDSRDPLVGE--SLKRQGFQENY 97



 Score = 32.3 bits (72), Expect = 2.2
 Identities = 14/44 (31%), Positives = 26/44 (59%)

Query: 364 NPGCVVIDGMPPGVVFKAPGYLEISSMRRILEAAEFIKFTVIRP 407
           +P  + + G+P G+  + P    I+ + +ILEA+  I+F + RP
Sbjct: 2   HPEELFVVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRP 45


>gi|239508897 PREDICTED: similar to hCG1983816 [Homo sapiens]
          Length = 265

 Score = 87.8 bits (216), Expect = 4e-17
 Identities = 48/134 (35%), Positives = 80/134 (59%), Gaps = 10/134 (7%)

Query: 317 DNEKERLSSIEKIKQLREQVNDLFSRKFGEAIGVDFPVKVPYRKITFNPGCVVIDGMPPG 376
           +N   RL  I+    LREQV +LF++ +GEA+G+ +PV+VPY+ I  NPG ++I+ +PPG
Sbjct: 95  ENYDARLLRIDIANTLREQVQELFNKTYGEALGIKYPVQVPYKWIKSNPGSMIIEELPPG 154

Query: 377 VVFKAPGYLEISSMRRILEAAEFIKFTVIRPLPGL-------ELSNVGKRKI-DQEGRVF 428
           ++F+ P      ++ RIL  A  I FTV RP  GL       + + +G+  + +Q   +F
Sbjct: 155 ILFRKP--FGSQNLERILAMANKITFTVTRPFQGLIRKPDEDDTNRLGEVILQEQVKELF 212

Query: 429 QEKWERAYFFVEVQ 442
            EK+ +  + ++ Q
Sbjct: 213 NEKYSQCLWLLQQQ 226



 Score = 49.7 bits (117), Expect = 1e-05
 Identities = 27/79 (34%), Positives = 45/79 (56%), Gaps = 2/79 (2%)

Query: 107 LRKAVEDYFCFCYGKALGTTVMVPVPYEKMLRDQSAVVVQGLPEGVAFQHPENYDLATLK 166
           LR+ V++ F   YG+ALG    V VPY+ +  +  +++++ LP G+ F+ P  +    L+
Sbjct: 110 LREQVQELFNKTYGEALGIKYPVQVPYKWIKSNPGSMIIEELPPGILFRKP--FGSQNLE 167

Query: 167 WILENKAGISFIINRPFLG 185
            IL     I+F + RPF G
Sbjct: 168 RILAMANKITFTVTRPFQG 186



 Score = 37.7 bits (86), Expect = 0.051
 Identities = 32/99 (32%), Positives = 45/99 (45%), Gaps = 9/99 (9%)

Query: 145 VQGLPEGVAFQHPENYDLATLKWILENKAGISFIINRPFLGPESQLGGPGMVTDAERSIV 204
           V GLPEG++ + P  + +A L  ILE    I F+I RP L  E   G    + D++    
Sbjct: 8   VVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRPKLLTE---GVKEPIVDSQ---- 60

Query: 205 SPSESCGPINVKTEPMEDSGISLKAEAVSVKKESEDPNY 243
             + S G       P  DS   L  E  S+K++    NY
Sbjct: 61  GTASSLGFSPPALPPERDSRDPLVGE--SLKRQGFQENY 97



 Score = 32.3 bits (72), Expect = 2.2
 Identities = 14/44 (31%), Positives = 26/44 (59%)

Query: 364 NPGCVVIDGMPPGVVFKAPGYLEISSMRRILEAAEFIKFTVIRP 407
           +P  + + G+P G+  + P    I+ + +ILEA+  I+F + RP
Sbjct: 2   HPEELFVVGLPEGISLRRPNCFGIAKLWKILEASNSIQFVIKRP 45


>gi|239741279 PREDICTED: similar to FLJ00310 protein [Homo
          sapiens]
          Length = 561

 Score = 42.4 bits (98), Expect = 0.002
 Identities = 27/41 (65%), Positives = 31/41 (75%), Gaps = 7/41 (17%)

Query: 1  MAQVAVSTLP------VEEESSSETRMVVTFLVSALESMCK 35
          MAQVAVSTLP      VE+E S E+RMVVTFL SAL+SM +
Sbjct: 1  MAQVAVSTLPIEDEESVEDEESLESRMVVTFL-SALDSMVR 40


>gi|116174778 centrosome spindle pole associated protein 1 isoform b
           [Homo sapiens]
          Length = 1221

 Score = 34.7 bits (78), Expect = 0.43
 Identities = 33/142 (23%), Positives = 61/142 (42%), Gaps = 13/142 (9%)

Query: 230 EAVSVKKESEDPNYYQYNMQGSHPSSTSNEVIEMELPMEDSTPLVPS------EEPNEDP 283
           EA   KKE E+    +YN+Q  H     N + E    M   +P+VP+       +    P
Sbjct: 810 EAERKKKEEEE----KYNLQLQHYCERDNLIGEETKHMRQPSPIVPALQNKIASKLQRPP 865

Query: 284 EAEVKIEGNTNSSSVTNSAAGVEDLNIVQVTVPDNEKERLSSIEKIKQLREQVNDLFSRK 343
             +  I    + SS++ + +        Q+     E+E+ + I ++ ++R+Q+     R 
Sbjct: 866 SVDSIIRSFIHESSMSRAQSPPVPARKNQLRA---EEEKKNVIMELSEMRKQLRSEERRL 922

Query: 344 FGEAIGVDFPVKVPYRKITFNP 365
               + +D   ++P RK   NP
Sbjct: 923 QERLLHMDSDDEIPIRKKERNP 944


>gi|116174789 centrosome spindle pole associated protein 1 isoform a
           [Homo sapiens]
          Length = 1256

 Score = 34.7 bits (78), Expect = 0.43
 Identities = 33/142 (23%), Positives = 61/142 (42%), Gaps = 13/142 (9%)

Query: 230 EAVSVKKESEDPNYYQYNMQGSHPSSTSNEVIEMELPMEDSTPLVPS------EEPNEDP 283
           EA   KKE E+    +YN+Q  H     N + E    M   +P+VP+       +    P
Sbjct: 845 EAERKKKEEEE----KYNLQLQHYCERDNLIGEETKHMRQPSPIVPALQNKIASKLQRPP 900

Query: 284 EAEVKIEGNTNSSSVTNSAAGVEDLNIVQVTVPDNEKERLSSIEKIKQLREQVNDLFSRK 343
             +  I    + SS++ + +        Q+     E+E+ + I ++ ++R+Q+     R 
Sbjct: 901 SVDSIIRSFIHESSMSRAQSPPVPARKNQLRA---EEEKKNVIMELSEMRKQLRSEERRL 957

Query: 344 FGEAIGVDFPVKVPYRKITFNP 365
               + +D   ++P RK   NP
Sbjct: 958 QERLLHMDSDDEIPIRKKERNP 979


>gi|19923268 protein-kinase, interferon-inducible double stranded
           RNA dependent inhibitor, repressor of (P58 repressor)
           [Homo sapiens]
          Length = 761

 Score = 34.3 bits (77), Expect = 0.57
 Identities = 18/51 (35%), Positives = 29/51 (56%), Gaps = 1/51 (1%)

Query: 535 EKLREKIRSFVAYSIAIDEITDINNTTQLAIFIRGVDENFDVSEELLDTVP 585
           E LRE +R    +SI  D++ DI     L + +R VDE+ ++ EE +  +P
Sbjct: 249 ETLRE-VRDSHFFSIITDDVVDIAGEEHLPVLVRFVDESHNLREEFIGFLP 298


>gi|31982906 cingulin-like 1 [Homo sapiens]
          Length = 1302

 Score = 33.9 bits (76), Expect = 0.74
 Identities = 24/118 (20%), Positives = 59/118 (50%), Gaps = 4/118 (3%)

Query: 227  LKAEAVSVKKESEDPNYYQYNMQGSHPSSTSNEVIEMELPMEDSTPLVPSEEPNEDPEAE 286
            L+ + +S++++++D      +++GS+ SS    V++ME  + +    + SEE +    A 
Sbjct: 1115 LECDKISLERQNKDLKSRIIHLEGSYRSSKEGLVVQMEARIAELEDRLESEERD---RAN 1171

Query: 287  VKIEGNTNSSSVTNSAAGVEDLNIVQVTVPDNEKERLSSIEK-IKQLREQVNDLFSRK 343
            +++        V      V+D ++      D    RL ++++ +++  E+++ L S K
Sbjct: 1172 LQLSNRRLERKVKELVMQVDDEHLSLTDQKDQLSLRLKAMKRQVEEAEEEIDRLESSK 1229


>gi|171543895 ataxin 2 [Homo sapiens]
          Length = 1313

 Score = 33.5 bits (75), Expect = 0.97
 Identities = 28/144 (19%), Positives = 55/144 (38%), Gaps = 11/144 (7%)

Query: 206 PSESCGPINVKTEPMEDSGISLKAEAVSVKKESEDPNYYQYNMQGSHPSS---------- 255
           PSE+  P   +T P   +  S+ +    +  ++  P   + N  G+ PS           
Sbjct: 655 PSEAATPPVARTSPSGGTWSSVVSGVPRLSPKTHRPRSPRQNSIGNTPSGPVLASPQAGI 714

Query: 256 TSNEVIEMELPMEDSTPLVPSEEPNEDPEAEVKIEGNTNSSSVTNSAAGVEDLNIVQVTV 315
              E + M +P    TP  P+      P +E K +         + A   E++   + + 
Sbjct: 715 IPTEAVAMPIPAASPTPASPASNRAVTPSSEAK-DSRLQDQRQNSPAGNKENIKPNETSP 773

Query: 316 PDNEKERLSSIEKIKQLREQVNDL 339
             ++ E       + + R+Q++DL
Sbjct: 774 SFSKAENKGISPVVSEHRKQIDDL 797


>gi|155969693 myomesin family, member 3 [Homo sapiens]
          Length = 1437

 Score = 33.1 bits (74), Expect = 1.3
 Identities = 21/64 (32%), Positives = 33/64 (51%), Gaps = 8/64 (12%)

Query: 282  DPEAEVKIEGNTNSSSVTNSAAGVEDLNIVQVTVPDNEKERLSS-------IEKIKQLRE 334
            DP+  VKIE   N S V     G+EDL    V V D +++  +S       +EK+K+L  
Sbjct: 941  DPQ-RVKIEDKVNKSKVILKEPGLEDLGTYSVIVTDADEDISASHTLTEEELEKLKKLSH 999

Query: 335  QVND 338
            ++ +
Sbjct: 1000 EIRN 1003


>gi|47132519 Ras association and pleckstrin homology domains 1
           isoform 1 [Homo sapiens]
          Length = 1250

 Score = 33.1 bits (74), Expect = 1.3
 Identities = 27/108 (25%), Positives = 54/108 (50%), Gaps = 18/108 (16%)

Query: 254 SSTSNEVIEMELPMEDSTPLVPSEEPNEDP-----EAEVKIEGNTNSSSVTNSAAGVEDL 308
           +S S +    +  +ED+ PLV ++           +AEV    N++ SS+T++A+ ++ L
Sbjct: 163 ASLSMDEAAQQSVLEDTKPLVTNQHRRTASAGTVSDAEVHSISNSSHSSITSAASSMDSL 222

Query: 309 NIVQVTVPD-----------NEKERLSSI--EKIKQLREQVNDLFSRK 343
           +I +VT P             E+E+ + +  EKI+   E++ +   +K
Sbjct: 223 DIDKVTRPQELDLTHQGQPITEEEQAAKLKAEKIRVALEKIKEAQVKK 270


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.133    0.390 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 35,470,961
Number of Sequences: 37866
Number of extensions: 1618289
Number of successful extensions: 5145
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 27
Number of HSP's successfully gapped in prelim test: 41
Number of HSP's that attempted gapping in prelim test: 4959
Number of HSP's gapped (non-prelim): 152
length of query: 949
length of database: 18,247,518
effective HSP length: 112
effective length of query: 837
effective length of database: 14,006,526
effective search space: 11723462262
effective search space used: 11723462262
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.