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Search of human proteins with 4827046
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4827046 U2 small nuclear RNA auxiliary factor 1-like 2 [Homo
sapiens]
(482 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4827046 U2 small nuclear RNA auxiliary factor 1-like 2 [Homo ... 991 0.0
gi|68800128 U2 small nuclear RNA auxillary factor 1 isoform b [H... 137 2e-32
gi|5803207 U2 small nuclear RNA auxillary factor 1 isoform a [Ho... 133 3e-31
gi|89038927 PREDICTED: similar to U2 small nuclear RNA auxillary... 107 2e-23
gi|94536809 U2 small nuclear RNA auxiliary factor 1-like 4 isofo... 106 5e-23
gi|89038281 PREDICTED: similar to U2 small nuclear RNA auxillary... 105 9e-23
gi|68800138 U2 small nuclear RNA auxillary factor 1 isoform c [H... 89 9e-18
gi|38146113 arginine/serine-rich coiled-coil 2 isoform b [Homo s... 87 4e-17
gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo s... 84 2e-16
gi|16905517 FUS interacting protein (serine-arginine rich) 1 iso... 81 2e-15
gi|52426743 cisplatin resistance-associated overexpressed protei... 77 3e-14
gi|19923485 cisplatin resistance-associated overexpressed protei... 77 3e-14
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 74 2e-13
gi|119226260 calcium homeostasis endoplasmic reticulum protein [... 74 2e-13
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 74 3e-13
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 73 5e-13
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m... 73 5e-13
gi|148746195 trichohyalin [Homo sapiens] 73 5e-13
gi|47271443 splicing factor, arginine/serine-rich 2 [Homo sapiens] 73 7e-13
gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sap... 72 9e-13
gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sap... 72 9e-13
gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo sap... 72 9e-13
gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo sapi... 72 9e-13
gi|115298682 HBxAg transactivated protein 2 [Homo sapiens] 72 1e-12
gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo sapi... 72 1e-12
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 71 2e-12
gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ... 71 2e-12
gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [... 71 2e-12
gi|102467235 inner centromere protein antigens 135/155kDa isofor... 71 2e-12
gi|102467242 inner centromere protein antigens 135/155kDa isofor... 71 2e-12
>gi|4827046 U2 small nuclear RNA auxiliary factor 1-like 2 [Homo
sapiens]
Length = 482
Score = 991 bits (2562), Expect = 0.0
Identities = 482/482 (100%), Positives = 482/482 (100%)
Query: 1 MAAPEKMTFPEKPSHKKYRAALKKEKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQLEE 60
MAAPEKMTFPEKPSHKKYRAALKKEKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQLEE
Sbjct: 1 MAAPEKMTFPEKPSHKKYRAALKKEKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQLEE 60
Query: 61 EKLLERERQRLHEEWLLREQKAQEEFRIKKEKEEAAKKRQEEQERKLKEQWEEQQRKERE 120
EKLLERERQRLHEEWLLREQKAQEEFRIKKEKEEAAKKRQEEQERKLKEQWEEQQRKERE
Sbjct: 61 EKLLERERQRLHEEWLLREQKAQEEFRIKKEKEEAAKKRQEEQERKLKEQWEEQQRKERE 120
Query: 121 EEEQKRQEKKEKEEALQKMLDQAENELENGTTWQNPEPPVDFRVMEKDRANCPFYSKTGA 180
EEEQKRQEKKEKEEALQKMLDQAENELENGTTWQNPEPPVDFRVMEKDRANCPFYSKTGA
Sbjct: 121 EEEQKRQEKKEKEEALQKMLDQAENELENGTTWQNPEPPVDFRVMEKDRANCPFYSKTGA 180
Query: 181 CRFGDRCSRKHNFPTSSPTLLIKSMFTTFGMEQCRRDDYDPDASLEYSEEETYQQFLDFY 240
CRFGDRCSRKHNFPTSSPTLLIKSMFTTFGMEQCRRDDYDPDASLEYSEEETYQQFLDFY
Sbjct: 181 CRFGDRCSRKHNFPTSSPTLLIKSMFTTFGMEQCRRDDYDPDASLEYSEEETYQQFLDFY 240
Query: 241 EDVLPEFKNVGKVIQFKVSCNLEPHLRGNVYVQYQSEEECQAALSLFNGRWYAGRQLQCE 300
EDVLPEFKNVGKVIQFKVSCNLEPHLRGNVYVQYQSEEECQAALSLFNGRWYAGRQLQCE
Sbjct: 241 EDVLPEFKNVGKVIQFKVSCNLEPHLRGNVYVQYQSEEECQAALSLFNGRWYAGRQLQCE 300
Query: 301 FCPVTRWKMAICGLFEIQQCPRGKHCNFLHVFRNPNNEFWEANRDIYLSPDRTGSSFGKN 360
FCPVTRWKMAICGLFEIQQCPRGKHCNFLHVFRNPNNEFWEANRDIYLSPDRTGSSFGKN
Sbjct: 301 FCPVTRWKMAICGLFEIQQCPRGKHCNFLHVFRNPNNEFWEANRDIYLSPDRTGSSFGKN 360
Query: 361 SERRERMGHHDDYYSRLRGRRNPSPDHSYKRNGESERKSSRHRGKKSHKRTSKSRERHNS 420
SERRERMGHHDDYYSRLRGRRNPSPDHSYKRNGESERKSSRHRGKKSHKRTSKSRERHNS
Sbjct: 361 SERRERMGHHDDYYSRLRGRRNPSPDHSYKRNGESERKSSRHRGKKSHKRTSKSRERHNS 420
Query: 421 RSRGRNRDRSRDRSRGRGSRSRSRSRSRRSRRSRSQSSSRSRSRGRRRSGNRDRTVQSPK 480
RSRGRNRDRSRDRSRGRGSRSRSRSRSRRSRRSRSQSSSRSRSRGRRRSGNRDRTVQSPK
Sbjct: 421 RSRGRNRDRSRDRSRGRGSRSRSRSRSRRSRRSRSQSSSRSRSRGRRRSGNRDRTVQSPK 480
Query: 481 SK 482
SK
Sbjct: 481 SK 482
>gi|68800128 U2 small nuclear RNA auxillary factor 1 isoform b [Homo
sapiens]
Length = 240
Score = 137 bits (346), Expect = 2e-32
Identities = 85/239 (35%), Positives = 125/239 (52%), Gaps = 17/239 (7%)
Query: 166 EKDRANCPFYSKTGACRFGDRCSRKHNFPTSSPTLLIKSMFTTFGMEQCRRDDYDPDASL 225
EKD+ NC FY K GACR GDRCSR HN PT S T+LI++++ D +
Sbjct: 12 EKDKVNCSFYFKIGACRHGDRCSRLHNKPTFSQTILIQNIYRNPQNSAQTADG----SHC 67
Query: 226 EYSEEETYQQFLDFYEDVLPEFKN-VGKVIQFKVSCNLEPHLRGNVYVQYQSEEECQAAL 284
S+ E + + +F+E+V E + G+V + V NL HL GNVYV+++ EE+ + A+
Sbjct: 68 AVSDVEMQEHYDEFFEEVFTEMEEKYGEVEEMNVCDNLGDHLVGNVYVKFRREEDAEKAV 127
Query: 285 SLFNGRWYAGRQLQCEFCPVTRWKMAICGLFEIQQCPRGKHCNFLHVFRNPNNEFWEANR 344
N RW+ G+ + E PVT ++ A C +E+ +C RG CNF+H+ P + E R
Sbjct: 128 IDLNNRWFNGQPIHAELSPVTDFREACCRQYEMGECTRGGFCNFMHL--KPISR--ELRR 183
Query: 345 DIYLSPDRTGSSFGKNSERRERMGHHDDYYSRLRGRRNPSPDHSYKRNGESERKSSRHR 403
++Y + S ++ ERR R SR RGR E +R+ SR R
Sbjct: 184 ELYGRRRKKHRSRSRSRERRSR--------SRDRGRGGGGGGGGGGGGRERDRRRSRDR 234
Score = 40.8 bits (94), Expect = 0.003
Identities = 24/61 (39%), Positives = 30/61 (49%), Gaps = 5/61 (8%)
Query: 397 RKSSRHRGKKSHKRTSKSRERHNSRSRGRNRDRSRDRSRGRGSRSRSRSRSRRSRRSRSQ 456
R+ R +K H+ S+SRER R R+RDR R G G R R RR R R +
Sbjct: 182 RRELYGRRRKKHRSRSRSRER-----RSRSRDRGRGGGGGGGGGGGGRERDRRRSRDRER 236
Query: 457 S 457
S
Sbjct: 237 S 237
Score = 38.5 bits (88), Expect = 0.014
Identities = 23/52 (44%), Positives = 27/52 (51%), Gaps = 1/52 (1%)
Query: 424 GRNRDRSRDRSRGRGSRSRSRSRSRRSRRSRSQSSSRSRSRGRRRSGNRDRT 475
GR R + R RSR R RSRSR R R R R RRRS +R+R+
Sbjct: 187 GRRRKKHRSRSRSRERRSRSRDRG-RGGGGGGGGGGGGRERDRRRSRDRERS 237
>gi|5803207 U2 small nuclear RNA auxillary factor 1 isoform a [Homo
sapiens]
Length = 240
Score = 133 bits (335), Expect = 3e-31
Identities = 83/239 (34%), Positives = 122/239 (51%), Gaps = 17/239 (7%)
Query: 166 EKDRANCPFYSKTGACRFGDRCSRKHNFPTSSPTLLIKSMFTTFGMEQCRRDDYDPDASL 225
EKD+ NC FY K GACR GDRCSR HN PT S T+ + +++ D
Sbjct: 12 EKDKVNCSFYFKIGACRHGDRCSRLHNKPTFSQTIALLNIYRNPQNSSQSADGL----RC 67
Query: 226 EYSEEETYQQFLDFYEDVLPEFKN-VGKVIQFKVSCNLEPHLRGNVYVQYQSEEECQAAL 284
S+ E + + +F+E+V E + G+V + V NL HL GNVYV+++ EE+ + A+
Sbjct: 68 AVSDVEMQEHYDEFFEEVFTEMEEKYGEVEEMNVCDNLGDHLVGNVYVKFRREEDAEKAV 127
Query: 285 SLFNGRWYAGRQLQCEFCPVTRWKMAICGLFEIQQCPRGKHCNFLHVFRNPNNEFWEANR 344
N RW+ G+ + E PVT ++ A C +E+ +C RG CNF+H+ P + E R
Sbjct: 128 IDLNNRWFNGQPIHAELSPVTDFREACCRQYEMGECTRGGFCNFMHL--KPISR--ELRR 183
Query: 345 DIYLSPDRTGSSFGKNSERRERMGHHDDYYSRLRGRRNPSPDHSYKRNGESERKSSRHR 403
++Y + S ++ ERR R SR RGR E +R+ SR R
Sbjct: 184 ELYGRRRKKHRSRSRSRERRSR--------SRDRGRGGGGGGGGGGGGRERDRRRSRDR 234
Score = 40.8 bits (94), Expect = 0.003
Identities = 24/61 (39%), Positives = 30/61 (49%), Gaps = 5/61 (8%)
Query: 397 RKSSRHRGKKSHKRTSKSRERHNSRSRGRNRDRSRDRSRGRGSRSRSRSRSRRSRRSRSQ 456
R+ R +K H+ S+SRER R R+RDR R G G R R RR R R +
Sbjct: 182 RRELYGRRRKKHRSRSRSRER-----RSRSRDRGRGGGGGGGGGGGGRERDRRRSRDRER 236
Query: 457 S 457
S
Sbjct: 237 S 237
Score = 38.5 bits (88), Expect = 0.014
Identities = 23/52 (44%), Positives = 27/52 (51%), Gaps = 1/52 (1%)
Query: 424 GRNRDRSRDRSRGRGSRSRSRSRSRRSRRSRSQSSSRSRSRGRRRSGNRDRT 475
GR R + R RSR R RSRSR R R R R RRRS +R+R+
Sbjct: 187 GRRRKKHRSRSRSRERRSRSRDRG-RGGGGGGGGGGGGRERDRRRSRDRERS 237
>gi|89038927 PREDICTED: similar to U2 small nuclear RNA auxillary
factor 1 [Homo sapiens]
Length = 243
Score = 107 bits (267), Expect = 2e-23
Identities = 66/211 (31%), Positives = 103/211 (48%), Gaps = 18/211 (8%)
Query: 168 DRANCPFYSKTGACRFGDRCSRKHNFPTSSPTLLIKSMFTTFGMEQCRRDDYDPDAS--- 224
++ NC F K GAC GDRCS H+ PT S T+ + +++ C + A
Sbjct: 12 EKVNCSFDFKIGACLHGDRCSWLHHKPTFSQTIALLNIY-------CNPQNASQSADGLR 64
Query: 225 LEYSEEETYQQFLDFYEDVLPEF-KNVGKVIQFKVSCNLEPHLRGNVYVQYQSEEECQAA 283
S+ E + + +F+E+V E + G+V + V NL HL GNVY + EE+ + A
Sbjct: 65 CALSDVEVQEHYDEFFEEVFIELGEKYGEVEEMNVCDNLGDHLVGNVYFKLPREEDAEKA 124
Query: 284 LSLFNGRWYAGRQLQCEFCPVTRWKMAICGLFEIQQCPRGKHCNFLH---VFRNPNNEFW 340
+ N RW+ G+ + E PVT ++ A C +E+ +C RG CNF+H + R E
Sbjct: 125 VIDLNNRWFNGQPIHAELSPVTDFRGACCRQYEMGECTRGGFCNFMHLKPISRELRRELC 184
Query: 341 EANRDIYLSPDRTGSSFGKNSERRERMGHHD 371
R + S R+ ++ +R GH D
Sbjct: 185 GQRRKKHRSRSRSRERHSRSGDR----GHGD 211
Score = 30.4 bits (67), Expect = 3.7
Identities = 17/53 (32%), Positives = 23/53 (43%)
Query: 405 KKSHKRTSKSRERHNSRSRGRNRDRSRDRSRGRGSRSRSRSRSRRSRRSRSQS 457
+K H+ S+SRERH+ + D G R R RR R R +S
Sbjct: 188 RKKHRSRSRSRERHSRSGDRGHGDGGGGGGGGGPGGGGGRERDRRRLRDRERS 240
>gi|94536809 U2 small nuclear RNA auxiliary factor 1-like 4 isoform
1 [Homo sapiens]
Length = 181
Score = 106 bits (264), Expect = 5e-23
Identities = 69/226 (30%), Positives = 101/226 (44%), Gaps = 57/226 (25%)
Query: 166 EKDRANCPFYSKTGACRFGDRCSRKHNFPTSSPTLLIKSMFTTFGMEQCRRDDYDPDASL 225
EKD+ NC FY K G CR GDRCSR HN PT S
Sbjct: 12 EKDKVNCSFYFKIGVCRHGDRCSRLHNKPTFS---------------------------- 43
Query: 226 EYSEEETYQQFLDFYEDVLPEFKNVGKVIQFKVSCNLEPHLRGNVYVQYQSEEECQAALS 285
+E + + + Y G++ + V NL HL GNVYV+++ EE+ + A++
Sbjct: 44 ----QEVFTELQEKY----------GEIEEMNVCDNLGDHLVGNVYVKFRREEDGERAVA 89
Query: 286 LFNGRWYAGRQLQCEFCPVTRWKMAICGLFEIQQCPRGKHCNFLHVFRNPNNEFWEANRD 345
+ RW+ G+ + E PVT ++ + C +E+ +C RG CNF+H+ N R
Sbjct: 90 ELSNRWFNGQAVHGELSPVTDFRESCCRQYEMGECTRGGFCNFMHLRPISQN----LQRQ 145
Query: 346 IYLSPDRTGSSFGKNSERRERMGHHDDYYSRLRGRRNPSPDHSYKR 391
+Y G+ RR H ++ R R R SPDH + R
Sbjct: 146 LY----------GRGPRRRSPPRFHTGHHPRERNHR-CSPDHWHGR 180
>gi|89038281 PREDICTED: similar to U2 small nuclear RNA auxillary
factor 1 [Homo sapiens]
Length = 243
Score = 105 bits (262), Expect = 9e-23
Identities = 66/211 (31%), Positives = 102/211 (48%), Gaps = 18/211 (8%)
Query: 168 DRANCPFYSKTGACRFGDRCSRKHNFPTSSPTLLIKSMFTTFGMEQCRRDDYDPDAS--- 224
++ NC F K GAC GDRCS H+ PT S T+ + +++ C + A
Sbjct: 12 EKVNCSFDFKIGACLHGDRCSWLHHKPTFSQTIALLNIY-------CNPQNASQSADGLR 64
Query: 225 LEYSEEETYQQFLDFYEDVLPEF-KNVGKVIQFKVSCNLEPHLRGNVYVQYQSEEECQAA 283
S+ E + +F+E+V E + G+V + V NL HL GNVY + EE+ + A
Sbjct: 65 CALSDVEVQEHSDEFFEEVFIELGEKYGEVEEMNVCDNLGDHLVGNVYFKLPREEDAEKA 124
Query: 284 LSLFNGRWYAGRQLQCEFCPVTRWKMAICGLFEIQQCPRGKHCNFLH---VFRNPNNEFW 340
+ N RW+ G+ + E PVT ++ A C +E+ +C RG CNF+H + R E
Sbjct: 125 VIDLNNRWFNGQPIHAELSPVTDFRGACCRQYEMGECTRGGFCNFMHLKPISRELRRELC 184
Query: 341 EANRDIYLSPDRTGSSFGKNSERRERMGHHD 371
R + S R+ ++ +R GH D
Sbjct: 185 GQRRKKHRSRSRSRERHSRSGDR----GHGD 211
Score = 30.4 bits (67), Expect = 3.7
Identities = 17/53 (32%), Positives = 23/53 (43%)
Query: 405 KKSHKRTSKSRERHNSRSRGRNRDRSRDRSRGRGSRSRSRSRSRRSRRSRSQS 457
+K H+ S+SRERH+ + D G R R RR R R +S
Sbjct: 188 RKKHRSRSRSRERHSRSGDRGHGDGGGGGGGGGPGGGGGRERDRRRLRDRERS 240
>gi|68800138 U2 small nuclear RNA auxillary factor 1 isoform c [Homo
sapiens]
Length = 167
Score = 89.0 bits (219), Expect = 9e-18
Identities = 56/171 (32%), Positives = 88/171 (51%), Gaps = 13/171 (7%)
Query: 234 QQFLDFYEDVLPEFKN-VGKVIQFKVSCNLEPHLRGNVYVQYQSEEECQAALSLFNGRWY 292
+ + +F+E+V E + G+V + V NL HL GNVYV+++ EE+ + A+ N RW+
Sbjct: 3 EHYDEFFEEVFTEMEEKYGEVEEMNVCDNLGDHLVGNVYVKFRREEDAEKAVIDLNNRWF 62
Query: 293 AGRQLQCEFCPVTRWKMAICGLFEIQQCPRGKHCNFLHVFRNPNNEFWEANRDIYLSPDR 352
G+ + E PVT ++ A C +E+ +C RG CNF+H+ P + E R++Y +
Sbjct: 63 NGQPIHAELSPVTDFREACCRQYEMGECTRGGFCNFMHL--KPISR--ELRRELYGRRRK 118
Query: 353 TGSSFGKNSERRERMGHHDDYYSRLRGRRNPSPDHSYKRNGESERKSSRHR 403
S ++ ERR R SR RGR E +R+ SR R
Sbjct: 119 KHRSRSRSRERRSR--------SRDRGRGGGGGGGGGGGGRERDRRRSRDR 161
Score = 40.8 bits (94), Expect = 0.003
Identities = 24/61 (39%), Positives = 30/61 (49%), Gaps = 5/61 (8%)
Query: 397 RKSSRHRGKKSHKRTSKSRERHNSRSRGRNRDRSRDRSRGRGSRSRSRSRSRRSRRSRSQ 456
R+ R +K H+ S+SRER R R+RDR R G G R R RR R R +
Sbjct: 109 RRELYGRRRKKHRSRSRSRER-----RSRSRDRGRGGGGGGGGGGGGRERDRRRSRDRER 163
Query: 457 S 457
S
Sbjct: 164 S 164
Score = 38.5 bits (88), Expect = 0.014
Identities = 23/52 (44%), Positives = 27/52 (51%), Gaps = 1/52 (1%)
Query: 424 GRNRDRSRDRSRGRGSRSRSRSRSRRSRRSRSQSSSRSRSRGRRRSGNRDRT 475
GR R + R RSR R RSRSR R R R R RRRS +R+R+
Sbjct: 114 GRRRKKHRSRSRSRERRSRSRDRG-RGGGGGGGGGGGGRERDRRRSRDRERS 164
>gi|38146113 arginine/serine-rich coiled-coil 2 isoform b [Homo
sapiens]
Length = 375
Score = 86.7 bits (213), Expect = 4e-17
Identities = 58/143 (40%), Positives = 82/143 (57%), Gaps = 6/143 (4%)
Query: 345 DIYLSPDRTGSSFGKNSERRERMGHHDDYYSRLRGR-RNPSPDHSYKRNGESERKSSR-- 401
+ +L R S K+S++ + H+D +S +GR R S ++ R+ ERKSSR
Sbjct: 5 NFFLKQGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGR 64
Query: 402 -HRGKKSHKRTSKSRERHNSRSRGRNRDRSRDRSRGRGSRSRSRSRSR-RSRRSRSQSSS 459
H +S +R +SR R +SR R+R+R + RSR R R +SRSRSR R RR RS+S S
Sbjct: 65 SHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSR-ERKKSRSRSRERKRRIRSRSRS 123
Query: 460 RSRSRGRRRSGNRDRTVQSPKSK 482
RSR R R RS +R R+ + K
Sbjct: 124 RSRHRHRTRSRSRTRSRSRDRKK 146
Score = 71.2 bits (173), Expect = 2e-12
Identities = 49/126 (38%), Positives = 64/126 (50%), Gaps = 15/126 (11%)
Query: 356 SFGKNSERRERMGHHDDYYSRLRGRRNPSPDHSYKRNGES-------ERKSSRHRGKKSH 408
S K ER + +D + R + + HS R+ E ERK SR R ++
Sbjct: 35 SSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERK 94
Query: 409 KRTSKSRERHNSRSRGRNRDRSRDRSRGRGSRSRSRSRSRRSRRSRSQSSSRSRSRGRRR 468
K S+SRER SRSR R R R RSRSRSRSR R+RS+S +RSRSR R++
Sbjct: 95 KSRSRSRERKKSRSRSRERKRR--------IRSRSRSRSRHRHRTRSRSRTRSRSRDRKK 146
Query: 469 SGNRDR 474
+ R
Sbjct: 147 RIEKPR 152
Score = 61.2 bits (147), Expect = 2e-09
Identities = 47/129 (36%), Positives = 59/129 (45%), Gaps = 11/129 (8%)
Query: 348 LSPDRTGSSFGKNSERRERMGH-HDDYYSRLRGRRNPSPDHSYKRNGESERKSSRHRGKK 406
L+ G K ER+ G H SR R R+ S + R+ ERK SR R ++
Sbjct: 43 LNSSENGEDRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRE 102
Query: 407 SHKRTSKSRERHN---------SRSRGRNRDRSRDRSRGRGSRSRSRSRSRRSRRSRSQS 457
K S+SRER SR R R R RSR RSR R R + + RR RS S++
Sbjct: 103 RKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRTRSRSR-DRKKRIEKPRRFSRSLSRT 161
Query: 458 SSRSRSRGR 466
S RGR
Sbjct: 162 PSPPPFRGR 170
Score = 31.6 bits (70), Expect = 1.7
Identities = 18/110 (16%), Positives = 47/110 (42%)
Query: 23 KKEKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQLEEEKLLERERQRLHEEWLLREQKA 82
K + KK + E ++ + E ++ + + K + R R H RE++
Sbjct: 17 KDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRERRH 76
Query: 83 QEEFRIKKEKEEAAKKRQEEQERKLKEQWEEQQRKEREEEEQKRQEKKEK 132
+ R +K+ +++R++ + R + + + +ER+ + R + +
Sbjct: 77 RSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSR 126
Score = 30.0 bits (66), Expect = 4.9
Identities = 22/109 (20%), Positives = 41/109 (37%), Gaps = 7/109 (6%)
Query: 24 KEKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQLEEEKLLERERQRLHEEWLLREQKAQ 83
+ KRK+R+ R S++ + E +K R R+R RE+K
Sbjct: 52 RHKRKERKSSRGRSHSRSRSRERRHRS-----RSRERKKSRSRSRERKKSRSRSRERKKS 106
Query: 84 EEFRIKKEKEEAAKKRQEEQERKLKEQWEEQQRKEREEEEQKRQEKKEK 132
+E++ + R + R + + R + +KR EK +
Sbjct: 107 RS--RSRERKRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRR 153
>gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo
sapiens]
Length = 434
Score = 84.3 bits (207), Expect = 2e-16
Identities = 57/136 (41%), Positives = 79/136 (58%), Gaps = 6/136 (4%)
Query: 352 RTGSSFGKNSERRERMGHHDDYYSRLRGR-RNPSPDHSYKRNGESERKSSR---HRGKKS 407
R S K+S++ + H+D +S +GR R S ++ R+ ERKSSR H +S
Sbjct: 71 RRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRS 130
Query: 408 HKRTSKSRERHNSRSRGRNRDRSRDRSRGRGSRSRSRSRSR-RSRRSRSQSSSRSRSRGR 466
+R +SR R +SR R+R+R + RSR R R +SRSRSR R RR RS+S SRSR R R
Sbjct: 131 RERRHRSRSRERKKSRSRSRERKKSRSRSR-ERKKSRSRSRERKRRIRSRSRSRSRHRHR 189
Query: 467 RRSGNRDRTVQSPKSK 482
RS +R R+ + K
Sbjct: 190 TRSRSRTRSRSRDRKK 205
Score = 77.4 bits (189), Expect = 3e-14
Identities = 54/154 (35%), Positives = 80/154 (51%), Gaps = 13/154 (8%)
Query: 334 NPNNEFWEANRDIYLSPDRTGSSFGKNSER-RERMGHHDD----YYSRLR---GRRNPSP 385
+P+ + + ++ +SP + + ++ R RER D+ + SR R GRR+ S
Sbjct: 17 SPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSRSRSKEGRRHESK 76
Query: 386 DHSYKRNGESERKSSRHRGKKSHKRTSKSR---ERHNSRSRGRNRDRSRDRSRGRGSRSR 442
D S K++ E H K +R + S +RH + R +R RS RSR R R R
Sbjct: 77 DKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRERRHR 136
Query: 443 SRSRSRRSRRSRSQS--SSRSRSRGRRRSGNRDR 474
SRSR R+ RSRS+ SRSRSR R++S +R R
Sbjct: 137 SRSRERKKSRSRSRERKKSRSRSRERKKSRSRSR 170
Score = 71.2 bits (173), Expect = 2e-12
Identities = 49/126 (38%), Positives = 64/126 (50%), Gaps = 15/126 (11%)
Query: 356 SFGKNSERRERMGHHDDYYSRLRGRRNPSPDHSYKRNGES-------ERKSSRHRGKKSH 408
S K ER + +D + R + + HS R+ E ERK SR R ++
Sbjct: 94 SSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERK 153
Query: 409 KRTSKSRERHNSRSRGRNRDRSRDRSRGRGSRSRSRSRSRRSRRSRSQSSSRSRSRGRRR 468
K S+SRER SRSR R R R RSRSRSRSR R+RS+S +RSRSR R++
Sbjct: 154 KSRSRSRERKKSRSRSRERKRR--------IRSRSRSRSRHRHRTRSRSRTRSRSRDRKK 205
Query: 469 SGNRDR 474
+ R
Sbjct: 206 RIEKPR 211
Score = 61.2 bits (147), Expect = 2e-09
Identities = 47/129 (36%), Positives = 59/129 (45%), Gaps = 11/129 (8%)
Query: 348 LSPDRTGSSFGKNSERRERMGH-HDDYYSRLRGRRNPSPDHSYKRNGESERKSSRHRGKK 406
L+ G K ER+ G H SR R R+ S + R+ ERK SR R ++
Sbjct: 102 LNSSENGEDRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRE 161
Query: 407 SHKRTSKSRERHN---------SRSRGRNRDRSRDRSRGRGSRSRSRSRSRRSRRSRSQS 457
K S+SRER SR R R R RSR RSR R R + + RR RS S++
Sbjct: 162 RKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRTRSRSR-DRKKRIEKPRRFSRSLSRT 220
Query: 458 SSRSRSRGR 466
S RGR
Sbjct: 221 PSPPPFRGR 229
Score = 45.8 bits (107), Expect = 9e-05
Identities = 28/79 (35%), Positives = 41/79 (51%), Gaps = 5/79 (6%)
Query: 390 KRNGESERKSSRHRGKKSHKRTSKSRERHNSRSRGRNRDRSRDRSR-----GRGSRSRSR 444
+R+G + K+S R KK + R + R+R RSR+R R GR RSRSR
Sbjct: 7 ERDGLAPEKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSRSR 66
Query: 445 SRSRRSRRSRSQSSSRSRS 463
S+ R S+ +SS + +S
Sbjct: 67 SKEGRRHESKDKSSKKHKS 85
Score = 43.9 bits (102), Expect = 3e-04
Identities = 48/155 (30%), Positives = 60/155 (38%), Gaps = 59/155 (38%)
Query: 384 SPDHSYKRNGESERKSSRHRGKKSHKRTSKSRERHNSR---SRGR-NRDRSRDR------ 433
SPD K+ E S R K H S+SR R R + GR +R RSR +
Sbjct: 17 SPDRDKKK--EQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSRSRSKEGRRHE 74
Query: 434 ---------------------------------------------SRGRGSRSRSRSRSR 448
SRGR S SRSRSR R
Sbjct: 75 SKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGR-SHSRSRSRER 133
Query: 449 RSR-RSRSQSSSRSRSRGRRRSGNRDRTVQSPKSK 482
R R RSR + SRSRSR R++S +R R + +S+
Sbjct: 134 RHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSR 168
Score = 33.5 bits (75), Expect = 0.44
Identities = 26/150 (17%), Positives = 61/150 (40%), Gaps = 14/150 (9%)
Query: 10 PEKPSHKKYRAALKKEKRKKRRQELARLRDSGLSQKE----EEEDTFIEEQQLEE----E 61
P H R+ + +RK++ R S KE E +D ++ + EE E
Sbjct: 33 PRASKHHYSRSRSRSRERKRKSDNEGRKHRSRSRSKEGRRHESKDKSSKKHKSEEHNDKE 92
Query: 62 KLLERERQRLH------EEWLLREQKAQEEFRIKKEKEEAAKKRQEEQERKLKEQWEEQQ 115
++ R+RL+ + +E+K+ + + + R +ERK ++
Sbjct: 93 HSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRER 152
Query: 116 RKEREEEEQKRQEKKEKEEALQKMLDQAEN 145
+K R ++++ + E +++ ++ +
Sbjct: 153 KKSRSRSRERKKSRSRSRERKRRIRSRSRS 182
Score = 31.6 bits (70), Expect = 1.7
Identities = 18/110 (16%), Positives = 47/110 (42%)
Query: 23 KKEKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQLEEEKLLERERQRLHEEWLLREQKA 82
K + KK + E ++ + E ++ + + K + R R H RE++
Sbjct: 76 KDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRERRH 135
Query: 83 QEEFRIKKEKEEAAKKRQEEQERKLKEQWEEQQRKEREEEEQKRQEKKEK 132
+ R +K+ +++R++ + R + + + +ER+ + R + +
Sbjct: 136 RSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSR 185
Score = 30.0 bits (66), Expect = 4.9
Identities = 22/109 (20%), Positives = 41/109 (37%), Gaps = 7/109 (6%)
Query: 24 KEKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQLEEEKLLERERQRLHEEWLLREQKAQ 83
+ KRK+R+ R S++ + E +K R R+R RE+K
Sbjct: 111 RHKRKERKSSRGRSHSRSRSRERRHRS-----RSRERKKSRSRSRERKKSRSRSRERKKS 165
Query: 84 EEFRIKKEKEEAAKKRQEEQERKLKEQWEEQQRKEREEEEQKRQEKKEK 132
+E++ + R + R + + R + +KR EK +
Sbjct: 166 RS--RSRERKRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRR 212
Score = 29.3 bits (64), Expect = 8.3
Identities = 24/99 (24%), Positives = 41/99 (41%), Gaps = 6/99 (6%)
Query: 38 RDSGLSQKEEEEDTFIEEQQLEEEKLLERERQRL--HEEWLLREQKAQEEFRIKKEKEEA 95
RD Q E + + RER+R +E R + +E R + K+++
Sbjct: 20 RDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSRSRSKEGRRHESKDKS 79
Query: 96 AKKRQEEQ----ERKLKEQWEEQQRKEREEEEQKRQEKK 130
+KK + E+ E + E E E+ KR+E+K
Sbjct: 80 SKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERK 118
>gi|16905517 FUS interacting protein (serine-arginine rich) 1
isoform 2 [Homo sapiens]
Length = 262
Score = 80.9 bits (198), Expect = 2e-15
Identities = 72/267 (26%), Positives = 111/267 (41%), Gaps = 57/267 (21%)
Query: 241 EDVLPEFKNVGKVIQFKVSCNLEPHL-RGNVYVQYQSEEECQAALSLFNGRWYAGRQLQC 299
ED+ EF G ++ V + RG YVQ++ + + AL + +W GRQ++
Sbjct: 24 EDLRREFGRYGPIVDVYVPLDFYTRRPRGFAYVQFEDVRDAEDALHNLDRKWICGRQIEI 83
Query: 300 EFCPVTRWKMAICGLFEIQQCPRGKHCNFLHVFRNPNNEFWEANRDIYLSP-----DRTG 354
+F R + PN + R++Y S DR
Sbjct: 84 QFAQGDR--------------------------KTPNQMKAKEGRNVYSSSRYDDYDRYR 117
Query: 355 SSFGKNSERRERMGHHDDY-YSRLRGRRNPSP-------------------DHSYKRNGE 394
S ++ ERR DY Y R RN P + S+ R+
Sbjct: 118 RSRSRSYERRRSRSRSFDYNYRRSYSPRNSRPTGRPRRSRSHSDNDRFKHRNRSFSRSKS 177
Query: 395 SERKSSRHRGKKSHKRTSKSRERHNSRSRGRNRDRSRDRSRGRGSRSRSRSRSRRSRRSR 454
+ R S+ + KK K S+SR ++++RG ++ S+ + GSR SR + RS+
Sbjct: 178 NSRSRSKSQPKKEMKAKSRSRSASHTKTRGTSKTDSKTHYKS-GSRYEKESRKKEPPRSK 236
Query: 455 SQSSSRSRSRGRRRSGNRDRTVQSPKS 481
SQS S+SRSR + RS R+ SPKS
Sbjct: 237 SQSRSQSRSRSKSRS----RSWTSPKS 259
>gi|52426743 cisplatin resistance-associated overexpressed protein
[Homo sapiens]
Length = 432
Score = 77.0 bits (188), Expect = 3e-14
Identities = 58/143 (40%), Positives = 73/143 (51%), Gaps = 16/143 (11%)
Query: 350 PDRTGSSFGKNSERRERMGHHD-DYYSRLRGRRNPSPDHSYKRNGESERKS-----SRHR 403
PDR + ER ER + + R R RR + +R + ER+ SRH
Sbjct: 241 PDRDERLKKEKQEREEREKEREREREERERKRRREEEEREKERARDRERRKRSRSRSRHS 300
Query: 404 GKKSHKRTSKSRERHNSRSRGRNRDRSRDRSRGRGSRSRSRSRSRRSRRSRSQSSSRSRS 463
+ S +R S+SR+ SRSR R R RSRDR RSRS RS R RSRS+ RS+S
Sbjct: 301 SRTSDRRCSRSRDHKRSRSRERRRSRSRDR-----RRSRSHDRSERKHRSRSRDRRRSKS 355
Query: 464 RGRR----RSGNRDRTVQSPKSK 482
R R+ RS +RDR Q KSK
Sbjct: 356 RDRKSYKHRSKSRDRE-QDRKSK 377
Score = 66.6 bits (161), Expect = 5e-11
Identities = 43/114 (37%), Positives = 61/114 (53%), Gaps = 14/114 (12%)
Query: 380 RRNPSPDHSYKRNGESERKSSRHRGKKSHKRTSKSRERHNSRSRG-RNRDRSRDRSRGRG 438
+R PD + E + + R +K +R + RER R R ++R+RDR R +
Sbjct: 236 KRTEEPDRDERLKKEKQEREER---EKEREREREERERKRRREEEEREKERARDRERRKR 292
Query: 439 SRSRSR----------SRSRRSRRSRSQSSSRSRSRGRRRSGNRDRTVQSPKSK 482
SRSRSR SRSR +RSRS+ RSRSR RRRS + DR+ + +S+
Sbjct: 293 SRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSR 346
Score = 65.5 bits (158), Expect = 1e-10
Identities = 44/128 (34%), Positives = 66/128 (51%), Gaps = 7/128 (5%)
Query: 359 KNSERRERMGHHDDYYSRLRGRR-NPSPDHSYKRNGESERKSSRHRGKKSHKRTSKSRER 417
++ ERR+R + SR RR + S DH KR+ ER+ SR R ++ + +S +
Sbjct: 285 RDRERRKRSRSRSRHSSRTSDRRCSRSRDH--KRSRSRERRRSRSRDRRRSRSHDRSERK 342
Query: 418 HNSRSRGRNRDRSRDR-SRGRGSRSRSRSRSRRSRRSRSQSSSRSRS---RGRRRSGNRD 473
H SRSR R R +SRDR S S+SR R + R+S+ + S +S G R + D
Sbjct: 343 HRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQSED 402
Query: 474 RTVQSPKS 481
+S +S
Sbjct: 403 TNTESKES 410
Score = 53.1 bits (126), Expect = 5e-07
Identities = 42/122 (34%), Positives = 58/122 (47%), Gaps = 18/122 (14%)
Query: 367 MGHHDDYYSRLRGRRNPSPDHSYKRNGESERKSSRHRGKKSHKRTSKSRERHNS-RSRGR 425
MG Y++++ + KR E +R + K+ + K RER R R R
Sbjct: 213 MGKQHMGYAKIKATVEELKEKLRKRTEEPDRDERLKKEKQEREEREKEREREREERERKR 272
Query: 426 NRD---RSRDRSRGRGSRSRSRSRSRRSRRSRSQSSSRS----------RSRGRRRSGNR 472
R+ R ++R+R R R RSRSRSR S S++S R RSR RRRS +R
Sbjct: 273 RREEEEREKERARDRERRKRSRSRSRHS----SRTSDRRCSRSRDHKRSRSRERRRSRSR 328
Query: 473 DR 474
DR
Sbjct: 329 DR 330
Score = 44.7 bits (104), Expect = 2e-04
Identities = 36/193 (18%), Positives = 85/193 (44%), Gaps = 15/193 (7%)
Query: 15 HKKYRAALKKEKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQLEEEKLLERERQRLHEE 74
+ K +A +++ K K R++ RD L ++++E + +E++ E E ERER+R EE
Sbjct: 220 YAKIKATVEELKEKLRKRTEEPDRDERLKKEKQEREEREKERERERE---ERERKRRREE 276
Query: 75 WLLREQKAQEEFRIKKEKEEA----------AKKRQEEQERKLKEQWEEQQRKEREEEEQ 124
+++A++ R K+ + + + ++ + + +E+ + R R
Sbjct: 277 EEREKERARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSH 336
Query: 125 KRQEKKEKEEALQKMLDQAENELENGTTWQNPEPPVDFRVMEKDRANCPFYSKTGACRFG 184
R E+K + + + ++ + ++ + D + EK++ K + + G
Sbjct: 337 DRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSD--DKKSSVKSG 394
Query: 185 DRCSRKHNFPTSS 197
R + + T S
Sbjct: 395 SREKQSEDTNTES 407
Score = 39.3 bits (90), Expect = 0.008
Identities = 28/147 (19%), Positives = 67/147 (45%), Gaps = 8/147 (5%)
Query: 11 EKPSHKKYRAALKKEKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQLEEEKLLERERQR 70
E+ ++ R ++++ + R + +R D S+ + + + E++ + +R R R
Sbjct: 277 EEREKERARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSR--DRRRSR 334
Query: 71 LHEEWLLREQKAQEEFRIKKEKEEAA-----KKRQEEQERKLKEQWEEQQRKEREEEEQK 125
H+ + + + R K ++ + K R EQ+RK KE+ + ++ +
Sbjct: 335 SHDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSG 394
Query: 126 RQEKKEKEEALQKMLDQAENELENGTT 152
+EK+ ++ + +NE+ NGT+
Sbjct: 395 SREKQSEDTNTESKESDTKNEV-NGTS 420
Score = 36.2 bits (82), Expect = 0.068
Identities = 41/184 (22%), Positives = 81/184 (44%), Gaps = 27/184 (14%)
Query: 34 LARLRDSGLSQKEEEEDTFIE-EQQLEEEKLLERERQRLHEEWLLREQKAQ--------- 83
L ++ + G K EE ++ +QL+EE+ L R E + +E++ +
Sbjct: 140 LQQIEELGSEGKVEEAQGMMKLVEQLKEERELLRSTTSTIESFAAQEKQMEVCEVCGAFL 199
Query: 84 ---------EEFRIKKEKEEAAKKRQ--EEQERKLKEQWEEQQRKEREEEEQKRQEKKEK 132
++ + K+ AK + EE + KL+++ EE R ER ++E +QE++E+
Sbjct: 200 IVGDAQSRVDDHLMGKQHMGYAKIKATVEELKEKLRKRTEEPDRDERLKKE--KQEREER 257
Query: 133 EEALQKMLDQAENELENGTTWQNPEPPVDFRVMEKDRANCPFYSKTGACRFGDRCSRKHN 192
E+ ++ ++ E + + E D ++ R+ S+T RCSR +
Sbjct: 258 EKEREREREERERKRRREEEEREKERARDRERRKRSRSRSRHSSRTS----DRRCSRSRD 313
Query: 193 FPTS 196
S
Sbjct: 314 HKRS 317
Score = 35.8 bits (81), Expect = 0.089
Identities = 21/136 (15%), Positives = 55/136 (40%), Gaps = 3/136 (2%)
Query: 11 EKPSHKKYRAALKKEKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQLEEEKLLERERQR 70
E+P + K+E+ ++ ++ + ++ EEE+ E+++ + + +R R R
Sbjct: 239 EEPDRDERLKKEKQEREEREKEREREREERERKRRREEEER--EKERARDRERRKRSRSR 296
Query: 71 LHEEWLLREQKAQEEFRIKKEKEEAAKKRQEEQERKLKEQWEEQQRKEREEEEQKRQEKK 130
+++ R K ++R ++R+ + +RK R +R+ K
Sbjct: 297 SRHSSRTSDRRCSRS-RDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKS 355
Query: 131 EKEEALQKMLDQAENE 146
++ + + E
Sbjct: 356 RDRKSYKHRSKSRDRE 371
>gi|19923485 cisplatin resistance-associated overexpressed protein
[Homo sapiens]
Length = 432
Score = 77.0 bits (188), Expect = 3e-14
Identities = 58/143 (40%), Positives = 73/143 (51%), Gaps = 16/143 (11%)
Query: 350 PDRTGSSFGKNSERRERMGHHD-DYYSRLRGRRNPSPDHSYKRNGESERKS-----SRHR 403
PDR + ER ER + + R R RR + +R + ER+ SRH
Sbjct: 241 PDRDERLKKEKQEREEREKEREREREERERKRRREEEEREKERARDRERRKRSRSRSRHS 300
Query: 404 GKKSHKRTSKSRERHNSRSRGRNRDRSRDRSRGRGSRSRSRSRSRRSRRSRSQSSSRSRS 463
+ S +R S+SR+ SRSR R R RSRDR RSRS RS R RSRS+ RS+S
Sbjct: 301 SRTSDRRCSRSRDHKRSRSRERRRSRSRDR-----RRSRSHDRSERKHRSRSRDRRRSKS 355
Query: 464 RGRR----RSGNRDRTVQSPKSK 482
R R+ RS +RDR Q KSK
Sbjct: 356 RDRKSYKHRSKSRDRE-QDRKSK 377
Score = 66.6 bits (161), Expect = 5e-11
Identities = 43/114 (37%), Positives = 61/114 (53%), Gaps = 14/114 (12%)
Query: 380 RRNPSPDHSYKRNGESERKSSRHRGKKSHKRTSKSRERHNSRSRG-RNRDRSRDRSRGRG 438
+R PD + E + + R +K +R + RER R R ++R+RDR R +
Sbjct: 236 KRTEEPDRDERLKKEKQEREER---EKEREREREERERKRRREEEEREKERARDRERRKR 292
Query: 439 SRSRSR----------SRSRRSRRSRSQSSSRSRSRGRRRSGNRDRTVQSPKSK 482
SRSRSR SRSR +RSRS+ RSRSR RRRS + DR+ + +S+
Sbjct: 293 SRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSR 346
Score = 65.5 bits (158), Expect = 1e-10
Identities = 44/128 (34%), Positives = 66/128 (51%), Gaps = 7/128 (5%)
Query: 359 KNSERRERMGHHDDYYSRLRGRR-NPSPDHSYKRNGESERKSSRHRGKKSHKRTSKSRER 417
++ ERR+R + SR RR + S DH KR+ ER+ SR R ++ + +S +
Sbjct: 285 RDRERRKRSRSRSRHSSRTSDRRCSRSRDH--KRSRSRERRRSRSRDRRRSRSHDRSERK 342
Query: 418 HNSRSRGRNRDRSRDR-SRGRGSRSRSRSRSRRSRRSRSQSSSRSRS---RGRRRSGNRD 473
H SRSR R R +SRDR S S+SR R + R+S+ + S +S G R + D
Sbjct: 343 HRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSGSREKQSED 402
Query: 474 RTVQSPKS 481
+S +S
Sbjct: 403 TNTESKES 410
Score = 53.1 bits (126), Expect = 5e-07
Identities = 42/122 (34%), Positives = 58/122 (47%), Gaps = 18/122 (14%)
Query: 367 MGHHDDYYSRLRGRRNPSPDHSYKRNGESERKSSRHRGKKSHKRTSKSRERHNS-RSRGR 425
MG Y++++ + KR E +R + K+ + K RER R R R
Sbjct: 213 MGKQHMGYAKIKATVEELKEKLRKRTEEPDRDERLKKEKQEREEREKEREREREERERKR 272
Query: 426 NRD---RSRDRSRGRGSRSRSRSRSRRSRRSRSQSSSRS----------RSRGRRRSGNR 472
R+ R ++R+R R R RSRSRSR S S++S R RSR RRRS +R
Sbjct: 273 RREEEEREKERARDRERRKRSRSRSRHS----SRTSDRRCSRSRDHKRSRSRERRRSRSR 328
Query: 473 DR 474
DR
Sbjct: 329 DR 330
Score = 44.7 bits (104), Expect = 2e-04
Identities = 36/193 (18%), Positives = 85/193 (44%), Gaps = 15/193 (7%)
Query: 15 HKKYRAALKKEKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQLEEEKLLERERQRLHEE 74
+ K +A +++ K K R++ RD L ++++E + +E++ E E ERER+R EE
Sbjct: 220 YAKIKATVEELKEKLRKRTEEPDRDERLKKEKQEREEREKERERERE---ERERKRRREE 276
Query: 75 WLLREQKAQEEFRIKKEKEEA----------AKKRQEEQERKLKEQWEEQQRKEREEEEQ 124
+++A++ R K+ + + + ++ + + +E+ + R R
Sbjct: 277 EEREKERARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSRDRRRSRSH 336
Query: 125 KRQEKKEKEEALQKMLDQAENELENGTTWQNPEPPVDFRVMEKDRANCPFYSKTGACRFG 184
R E+K + + + ++ + ++ + D + EK++ K + + G
Sbjct: 337 DRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSD--DKKSSVKSG 394
Query: 185 DRCSRKHNFPTSS 197
R + + T S
Sbjct: 395 SREKQSEDTNTES 407
Score = 39.3 bits (90), Expect = 0.008
Identities = 28/147 (19%), Positives = 67/147 (45%), Gaps = 8/147 (5%)
Query: 11 EKPSHKKYRAALKKEKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQLEEEKLLERERQR 70
E+ ++ R ++++ + R + +R D S+ + + + E++ + +R R R
Sbjct: 277 EEREKERARDRERRKRSRSRSRHSSRTSDRRCSRSRDHKRSRSRERRRSRSR--DRRRSR 334
Query: 71 LHEEWLLREQKAQEEFRIKKEKEEAA-----KKRQEEQERKLKEQWEEQQRKEREEEEQK 125
H+ + + + R K ++ + K R EQ+RK KE+ + ++ +
Sbjct: 335 SHDRSERKHRSRSRDRRRSKSRDRKSYKHRSKSRDREQDRKSKEKEKRGSDDKKSSVKSG 394
Query: 126 RQEKKEKEEALQKMLDQAENELENGTT 152
+EK+ ++ + +NE+ NGT+
Sbjct: 395 SREKQSEDTNTESKESDTKNEV-NGTS 420
Score = 36.2 bits (82), Expect = 0.068
Identities = 41/184 (22%), Positives = 81/184 (44%), Gaps = 27/184 (14%)
Query: 34 LARLRDSGLSQKEEEEDTFIE-EQQLEEEKLLERERQRLHEEWLLREQKAQ--------- 83
L ++ + G K EE ++ +QL+EE+ L R E + +E++ +
Sbjct: 140 LQQIEELGSEGKVEEAQGMMKLVEQLKEERELLRSTTSTIESFAAQEKQMEVCEVCGAFL 199
Query: 84 ---------EEFRIKKEKEEAAKKRQ--EEQERKLKEQWEEQQRKEREEEEQKRQEKKEK 132
++ + K+ AK + EE + KL+++ EE R ER ++E +QE++E+
Sbjct: 200 IVGDAQSRVDDHLMGKQHMGYAKIKATVEELKEKLRKRTEEPDRDERLKKE--KQEREER 257
Query: 133 EEALQKMLDQAENELENGTTWQNPEPPVDFRVMEKDRANCPFYSKTGACRFGDRCSRKHN 192
E+ ++ ++ E + + E D ++ R+ S+T RCSR +
Sbjct: 258 EKEREREREERERKRRREEEEREKERARDRERRKRSRSRSRHSSRTS----DRRCSRSRD 313
Query: 193 FPTS 196
S
Sbjct: 314 HKRS 317
Score = 35.8 bits (81), Expect = 0.089
Identities = 21/136 (15%), Positives = 55/136 (40%), Gaps = 3/136 (2%)
Query: 11 EKPSHKKYRAALKKEKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQLEEEKLLERERQR 70
E+P + K+E+ ++ ++ + ++ EEE+ E+++ + + +R R R
Sbjct: 239 EEPDRDERLKKEKQEREEREKEREREREERERKRRREEEER--EKERARDRERRKRSRSR 296
Query: 71 LHEEWLLREQKAQEEFRIKKEKEEAAKKRQEEQERKLKEQWEEQQRKEREEEEQKRQEKK 130
+++ R K ++R ++R+ + +RK R +R+ K
Sbjct: 297 SRHSSRTSDRRCSRS-RDHKRSRSRERRRSRSRDRRRSRSHDRSERKHRSRSRDRRRSKS 355
Query: 131 EKEEALQKMLDQAENE 146
++ + + E
Sbjct: 356 RDRKSYKHRSKSRDRE 371
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 74.3 bits (181), Expect = 2e-13
Identities = 47/151 (31%), Positives = 89/151 (58%), Gaps = 7/151 (4%)
Query: 5 EKMTFPEKPSHKKYRAALKKEKR----KKRRQELARLRDSGLSQKEEEEDTFIEEQQLEE 60
+KM E+ ++ +KE+R KK Q+ ++R+ +Q++E++ EE+ EE
Sbjct: 500 QKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREE 559
Query: 61 EKLLERERQRLHEEWLLREQ--KAQEEFRIKKEKEEAAKKRQEEQERKLKEQWEEQQRKE 118
E++ ERE++ EE ++REQ K QE+ +E+EE +++E+ + + ++ WE++++
Sbjct: 560 ERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMW 619
Query: 119 REEEEQKRQEKKEKE-EALQKMLDQAENELE 148
+EEE K QE++E E +KM +Q E E
Sbjct: 620 EQEEEDKMQEQEEMMWEQEEKMQEQEEKMWE 650
Score = 68.6 bits (166), Expect = 1e-11
Identities = 39/147 (26%), Positives = 84/147 (57%), Gaps = 3/147 (2%)
Query: 5 EKMTFPEKPSHKKYRAALKKEKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQLEEEKLL 64
EK T+ ++ ++ ++EK+ + +E+ R ++ + ++EE+ E+ +EEK+
Sbjct: 546 EKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQ 605
Query: 65 ERERQRLHEEWLLREQKAQEEFRIKKEKEEAAKKRQEEQERKLKEQWE---EQQRKEREE 121
E+E + +E + EQ+ +++ + ++E +++ +EQE K+ EQ E EQ+ K RE+
Sbjct: 606 EQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQ 665
Query: 122 EEQKRQEKKEKEEALQKMLDQAENELE 148
EE+ + ++++ E +KM Q E E
Sbjct: 666 EEKMQGQEEKMREQEEKMQGQEEKMRE 692
Score = 67.4 bits (163), Expect = 3e-11
Identities = 48/167 (28%), Positives = 96/167 (57%), Gaps = 18/167 (10%)
Query: 5 EKMTFPEKPSHKKYRAALKKEK----RKKRRQELARLRDSGLSQKEEEEDTFIEEQQL-- 58
EKM EK ++ + ++EK +KK R++ ++++ E+EE +E+++
Sbjct: 276 EKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWR 335
Query: 59 EEEKLLERERQRLHEEWLLREQKAQ--EEFRIKKEKEEAAKKRQE--EQERKLKEQ--WE 112
+EE+L E+E+Q +E +R+Q+ + E+ +EKEE +++++ EQE K++E+
Sbjct: 336 QEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIR 395
Query: 113 EQQRKEREEEEQKRQEKKEKEEALQKMLDQAENELENGTTWQNPEPP 159
E+++K REEEE R+++++ ++ + M +Q E E WQ P
Sbjct: 396 EREKKMREEEETMREQEEKMQKQEENMWEQEEKE------WQQQRLP 436
Score = 67.0 bits (162), Expect = 4e-11
Identities = 46/168 (27%), Positives = 96/168 (57%), Gaps = 5/168 (2%)
Query: 5 EKMTFPEKPSHKKYRAALKKEKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQL-EEEKL 63
E+M E+ ++ + K+E++ R++E RLR+ +E+EE +E++L E+EK
Sbjct: 234 EEMWRQEEELREQEKKIRKQEEKMWRQEE--RLREQEGKMREQEEKMRRQEKRLREQEKE 291
Query: 64 LERERQRLHEEWLLREQKAQEEFRIKKEKEEAAKKRQEEQERKLKEQWEEQQRKEREEEE 123
L + + L E+ LREQ+ Q + + +K E+ K R++E++ +E+ +Q K+ E+E
Sbjct: 292 LREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQE 351
Query: 124 QKRQEKKEKE-EALQKMLDQAENELENGTTWQNPEP-PVDFRVMEKDR 169
QK ++++E+ E +++ ++ E E W+ E + R+ E+++
Sbjct: 352 QKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREK 399
Score = 67.0 bits (162), Expect = 4e-11
Identities = 47/150 (31%), Positives = 88/150 (58%), Gaps = 12/150 (8%)
Query: 5 EKMTFPEKPSHKKYRAALKKEKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQLEEEKLL 64
EKM +K ++ + ++EK R +E R R+ + ++EE E+ Q +EEK+
Sbjct: 534 EKMREEKKTQEQEKKTWDQEEKM--REEERMREREKKMREEEEMMREQEEKMQEQEEKMR 591
Query: 65 ERERQRLHEEWLLREQKA----QEEFRIKKEKEEAAKKRQE---EQERKLKEQWE---EQ 114
E+E + +E ++EQ+ QEE ++E+E+ ++++E EQE K++EQ E EQ
Sbjct: 592 EQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQ 651
Query: 115 QRKEREEEEQKRQEKKEKEEALQKMLDQAE 144
+ K RE+EE+ R+++++ + +KM +Q E
Sbjct: 652 EEKMREQEEKMREQEEKMQGQEEKMREQEE 681
Score = 65.1 bits (157), Expect = 1e-10
Identities = 46/161 (28%), Positives = 92/161 (57%), Gaps = 11/161 (6%)
Query: 5 EKMTFPEKPSHKKYRAALKKEKR-----KKRRQELARLRDSGLSQKEEEEDTFIEEQQL- 58
EKM E+ ++ ++E+R K+ R++ ++RD E++E +E+++
Sbjct: 317 EKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMR 376
Query: 59 EEEKLLERERQRLHEEWLL-REQKAQEEFRIKKEKEEAAKKRQEEQERKLKEQWEEQQRK 117
E+EK+ E+E + EE + RE+K +EE +E+EE +K++E + +++W++Q+
Sbjct: 377 EQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLP 436
Query: 118 EREE---EEQKRQEKKEK-EEALQKMLDQAENELENGTTWQ 154
E++E E++K QE++EK E +K+ DQ E + W+
Sbjct: 437 EQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWR 477
Score = 64.7 bits (156), Expect = 2e-10
Identities = 47/158 (29%), Positives = 88/158 (55%), Gaps = 7/158 (4%)
Query: 5 EKMTFPEKPSHKKYRAALKKEKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQLEEEKLL 64
E++ EK ++ + +E+R + E RLR+ +E+E+ EE+ EEE++
Sbjct: 338 ERLWEQEKQMREQEQKMRDQEERMWEQDE--RLREKEERMREQEKMWEQEEKMQEEERIR 395
Query: 65 ERERQRLHEEWLLREQKA----QEEFRIKKEKEEAAKKRQEEQERKLKEQWEEQQRKERE 120
ERE++ EE +REQ+ QEE ++E++E ++R EQ+ KL EQ + Q+++E+
Sbjct: 396 EREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKI 455
Query: 121 -EEEQKRQEKKEKEEALQKMLDQAENELENGTTWQNPE 157
E+E+K ++++E +KM Q + + W+ E
Sbjct: 456 WEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEE 493
Score = 63.5 bits (153), Expect = 4e-10
Identities = 44/161 (27%), Positives = 91/161 (56%), Gaps = 11/161 (6%)
Query: 5 EKMTFPEKPSHKKYRAALKKEKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQL--EEEK 62
E+M EK K +R +E+ + ++ ++RD ++EE + ++++L +EE+
Sbjct: 466 EEMWGQEK---KMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEER 522
Query: 63 LLERERQRLHEEWLLREQKAQEEFRIKKEKEEAAKK--RQEEQERKLKEQWE---EQQRK 117
+ E+++ EE + E+K QE+ + ++EE ++ R E+E+K++E+ E EQ+ K
Sbjct: 523 MREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEK 582
Query: 118 EREEEEQKRQEKKEKEEALQKMLDQAENELE-NGTTWQNPE 157
+E+EE+ R+++++ E +KM +Q E E W+ E
Sbjct: 583 MQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEE 623
Score = 63.5 bits (153), Expect = 4e-10
Identities = 45/150 (30%), Positives = 81/150 (54%), Gaps = 12/150 (8%)
Query: 16 KKYRAALKKEKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQLEEEKLLERERQRLHEEW 75
K ++ K + KK +++ + D +EEE E++ EEE+++ + +++ E+
Sbjct: 528 KMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQ- 586
Query: 76 LLREQKAQEEFRIKKEKEEAAKKRQE---EQERKLKEQWEEQQRKERE----EEEQKRQE 128
E+K +E+ E+EE ++++E EQE K+ EQ EE + +E+E E+E+K QE
Sbjct: 587 ---EEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQE 643
Query: 129 KKEKE-EALQKMLDQAENELENGTTWQNPE 157
++EK E +KM +Q E E Q E
Sbjct: 644 QEEKMWEQEEKMREQEEKMREQEEKMQGQE 673
Score = 62.8 bits (151), Expect = 7e-10
Identities = 40/123 (32%), Positives = 76/123 (61%), Gaps = 6/123 (4%)
Query: 26 KRKKRRQELARLRDSGLSQKEEEEDTFIEEQQL--EEEKLLERERQRLHEEWLLREQKAQ 83
K KR+ E A+ + +E+ + +E++L +E+K+ ++E + +E LREQ+ +
Sbjct: 211 KELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGK 270
Query: 84 EEFRIKKEKEEAAKKRQEEQERKLKEQWEE--QQRKEREEEEQKRQEKKEKEEALQKMLD 141
R ++EK +KR EQE++L+EQ +E +Q+K RE+EEQ ++++++ E +KM +
Sbjct: 271 --MREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMRE 328
Query: 142 QAE 144
Q E
Sbjct: 329 QEE 331
Score = 62.8 bits (151), Expect = 7e-10
Identities = 40/153 (26%), Positives = 83/153 (54%), Gaps = 11/153 (7%)
Query: 5 EKMTFPEKPSHKKYRAALKKEKRKKRRQEL-----------ARLRDSGLSQKEEEEDTFI 53
+KM EK ++ + ++EK + + Q++ RLR+ +E+++
Sbjct: 473 KKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQ 532
Query: 54 EEQQLEEEKLLERERQRLHEEWLLREQKAQEEFRIKKEKEEAAKKRQEEQERKLKEQWEE 113
EE+ EE+K E+E++ +E +RE++ E K +EE + QEE+ ++ +E+ E
Sbjct: 533 EEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMRE 592
Query: 114 QQRKEREEEEQKRQEKKEKEEALQKMLDQAENE 146
Q+ K E+EE+ ++++++ E +KM +Q E +
Sbjct: 593 QEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEED 625
Score = 61.2 bits (147), Expect = 2e-09
Identities = 46/184 (25%), Positives = 95/184 (51%), Gaps = 31/184 (16%)
Query: 1 MAAPEKMTFPEKPSHKKYRAALKKEKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQ--- 57
M EKM E+ ++ R +E+ KK R+E +R+ +++EE+ + +E++
Sbjct: 375 MREQEKMWEQEEKMQEEERI---REREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQ 431
Query: 58 -----------LEEEKLLERERQRLHEEWLLREQK---AQEEFRIKKEKEEAAKKRQEEQ 103
E+EK+ E+E + +E +R+Q+ QE+ ++EK + + EQ
Sbjct: 432 QQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQ 491
Query: 104 ERKLKEQ----WEEQQR------KEREEEEQKRQEKKEKEEALQKMLDQAENELENGTTW 153
E K+++Q W++++R + RE+EE+ R++KK ++ +KM ++ + + + TW
Sbjct: 492 EEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQE-EKMREEKKTQEQEKKTW 550
Query: 154 QNPE 157
E
Sbjct: 551 DQEE 554
Score = 58.9 bits (141), Expect = 1e-08
Identities = 40/147 (27%), Positives = 80/147 (54%), Gaps = 14/147 (9%)
Query: 12 KPSHKKYRAALKKEKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQLE--EEKLLERERQ 69
+ ++ R K +++++ QE R+R+ +EEEE +E++++ EE + E+E
Sbjct: 369 REKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQE-- 426
Query: 70 RLHEEWLLREQKAQEEFRIKKEKEEAAKKRQEEQERKLKEQ---WEEQ-----QRKEREE 121
+EW + Q+E ++EK + +++ EQE K+++Q W ++ Q K RE+
Sbjct: 427 --EKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQ 484
Query: 122 EEQKRQEKKEKEEALQKMLDQAENELE 148
E+Q +++++ + QKM DQ E E
Sbjct: 485 EDQMWEQEEKMRDQEQKMWDQEERMWE 511
Score = 58.9 bits (141), Expect = 1e-08
Identities = 43/155 (27%), Positives = 81/155 (52%), Gaps = 11/155 (7%)
Query: 1 MAAPEKMTFPEKPSHKKYRAALKKEKRKKRRQELARLRDSGLSQKEEEEDTFIEE---QQ 57
M EK E+ ++ +++++ K R QE Q++EE+ EE +Q
Sbjct: 562 MREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQ 621
Query: 58 LEEEKLLERERQRLHEEWLLREQKA-----QEEFRIKKEKEEAAKKRQEEQERKLKEQWE 112
EE+K+ E+E +E ++EQ+ +E+ R ++EK +++ + QE K++EQ E
Sbjct: 622 EEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEE 681
Query: 113 E---QQRKEREEEEQKRQEKKEKEEALQKMLDQAE 144
+ Q+ K RE+EE+ R ++++ +KM Q E
Sbjct: 682 KMQGQEEKMREQEEKMRGQEEKMWGQEEKMWGQEE 716
Score = 56.6 bits (135), Expect = 5e-08
Identities = 38/162 (23%), Positives = 87/162 (53%), Gaps = 19/162 (11%)
Query: 5 EKMTFPEKPSHKKYRAALKKEKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQL------ 58
EKM E+ ++ ++E++ + ++E ++ + ++EEE+ +E+ +
Sbjct: 581 EKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEK 640
Query: 59 ---EEEKLLERERQRLHEEWLLREQK-----AQEEFRIKKEKEEAAKKRQEEQERKLKEQ 110
+EEK+ E+E + +E +REQ+ +E+ R ++EK + +++ EQE K++ Q
Sbjct: 641 MQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMRGQ 700
Query: 111 ----WEEQQRKEREEEEQKRQEK-KEKEEALQKMLDQAENEL 147
W ++++ +EE+ QE+ +EKEE ++ ++ + L
Sbjct: 701 EEKMWGQEEKMWGQEEKMWGQEEMREKEERIRDQKEKMQERL 742
Score = 52.8 bits (125), Expect = 7e-07
Identities = 41/150 (27%), Positives = 84/150 (56%), Gaps = 11/150 (7%)
Query: 5 EKMTFPEKPSHKKYRAALKKEK---RKKRRQELARLRDSGLSQKEEEEDTFIEEQQLEEE 61
E M E+ ++ R +KEK ++K +++ ++ + +++EE E++ +E
Sbjct: 420 ENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQE 479
Query: 62 KLLERERQRLHEEWLLREQKAQ---EEFRIKKEKEEAAKKRQEEQERKLKEQWEEQQRKE 118
K+ E+E Q +E +R+Q+ + +E R+ ++ E +K EE+ R+ K+ W+ Q+ K
Sbjct: 480 KMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREK--EERMREQKKMWQ-QEEKM 536
Query: 119 REEEEQKRQEKK--EKEEALQKMLDQAENE 146
REE++ + QEKK ++EE +++ E E
Sbjct: 537 REEKKTQEQEKKTWDQEEKMREEERMRERE 566
Score = 46.2 bits (108), Expect = 7e-05
Identities = 43/200 (21%), Positives = 90/200 (45%), Gaps = 14/200 (7%)
Query: 5 EKMTFPEKPSHKKYRAALKKEKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQLEEEKLL 64
+KM E+ ++ ++E++ ++E R ++ + ++EE+ E+ + +EEK+
Sbjct: 625 DKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQ 684
Query: 65 ERERQRLHEEWLLREQK----AQEEFRIKKEKEEAAKKRQEEQERKLKEQWEEQQRKERE 120
+E + +E +R Q+ QEE +E++ ++ E+E ++++Q E+ Q + E
Sbjct: 685 GQEEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMREKEERIRDQKEKMQERLPE 744
Query: 121 EEEQKRQEKKEKEEALQKM-----LDQAENELENGTTWQNPEPPVDFRVM--EKDRANCP 173
EE+ + + L M ++ A E G+ NP ++ K+ CP
Sbjct: 745 HEERCSEPCLPPSKVLCNMSHTGSVEPAGGEAGEGSPQDNPTAQEIMQLFCGMKNAQQCP 804
Query: 174 FYSKTGACRF---GDRCSRK 190
T F GD+ K
Sbjct: 805 GLGSTSCIPFFYRGDKRKMK 824
>gi|119226260 calcium homeostasis endoplasmic reticulum protein
[Homo sapiens]
Length = 916
Score = 74.3 bits (181), Expect = 2e-13
Identities = 54/127 (42%), Positives = 68/127 (53%), Gaps = 14/127 (11%)
Query: 359 KNSERRERMGHHDDYYSRLRGRR-------NPSPDHSYKRNGESERKSSRHRGKKSHKRT 411
+NSE E+ G ++ + +++R RR N P S R+ R SSR + S
Sbjct: 703 RNSEGWEQNGLYEFFRAKMRARRRKGQEKRNSGPSRSRSRSKSRGRSSSRSNSRSSKSSG 762
Query: 412 SKSRERHNSRSRGRNRDRSRDRSRGRGSRSRSRSRSRRSRRSRSQSSSRSRSRGRRRSGN 471
S SR R S SR +R RSR RSR R SRSRSRS+S RSRS+S S R RRRS +
Sbjct: 763 SYSRSRSRSCSRSYSRSRSRSRSRSRSSRSRSRSQS----RSRSKSYSPGR---RRRSRS 815
Query: 472 RDRTVQS 478
R T S
Sbjct: 816 RSPTPPS 822
Score = 59.3 bits (142), Expect = 8e-09
Identities = 45/106 (42%), Positives = 55/106 (51%), Gaps = 15/106 (14%)
Query: 385 PDHSYKRNGESERKSSRHR--GKKSHKRTSKSRERHNS-----RSRGRNRDRSRDRSRGR 437
P H RN E ++ + K R K +E+ NS RSR ++R RS RS R
Sbjct: 697 PSHDRPRNSEGWEQNGLYEFFRAKMRARRRKGQEKRNSGPSRSRSRSKSRGRSSSRSNSR 756
Query: 438 G-------SRSRSRSRSRRSRRSRSQSSSRSR-SRGRRRSGNRDRT 475
SRSRSRS SR RSRS+S SRSR SR R RS +R R+
Sbjct: 757 SSKSSGSYSRSRSRSCSRSYSRSRSRSRSRSRSSRSRSRSQSRSRS 802
Score = 50.4 bits (119), Expect = 3e-06
Identities = 42/131 (32%), Positives = 58/131 (44%), Gaps = 4/131 (3%)
Query: 333 RNPNNEFWEANRDIYLSPDRTGSSFGKNSERRERMGHHDDYYSRLRGRRNP-SPDHSYKR 391
R N+E WE N + + K E+R S+ RGR + S S K
Sbjct: 701 RPRNSEGWEQNGLYEFFRAKMRARRRKGQEKRNSGPSRSRSRSKSRGRSSSRSNSRSSKS 760
Query: 392 NGESERKSSRHRGKKSHKRTSKSRERHNS---RSRGRNRDRSRDRSRGRGSRSRSRSRSR 448
+G R SR + + S+SR R S RSR ++R RS+ S GR RSRSRS +
Sbjct: 761 SGSYSRSRSRSCSRSYSRSRSRSRSRSRSSRSRSRSQSRSRSKSYSPGRRRRSRSRSPTP 820
Query: 449 RSRRSRSQSSS 459
S +S+
Sbjct: 821 PSSAGLGSNSA 831
>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
Length = 245
Score = 73.9 bits (180), Expect = 3e-13
Identities = 42/143 (29%), Positives = 85/143 (59%), Gaps = 3/143 (2%)
Query: 11 EKPSHKKYRAALKKEKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQLEEEKLLERERQR 70
E+ K+ R KE +K +++ ++ G + KE +E EE++ EE K ER+++
Sbjct: 94 ERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEE 153
Query: 71 LHEEWLLREQKAQEEFRI---KKEKEEAAKKRQEEQERKLKEQWEEQQRKEREEEEQKRQ 127
+E +E+K +E ++ ++E++E +K ++++ER KE+ +E++RKER E +++R+
Sbjct: 154 REKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERK 213
Query: 128 EKKEKEEALQKMLDQAENELENG 150
+K+E+++ QK E E G
Sbjct: 214 KKEERKKERQKDRQTNWREKERG 236
Score = 68.9 bits (167), Expect = 9e-12
Identities = 40/143 (27%), Positives = 82/143 (57%), Gaps = 15/143 (10%)
Query: 11 EKPSHKKYRAALKKEKRKKRRQELARLRDSGLSQKEE--------EEDTFIEEQQLEEEK 62
E+ ++ R K+E+ K+R++E + G +KEE E++ E++ + +K
Sbjct: 58 ERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEKEKRKK 117
Query: 63 LLERERQRLHEEWLLREQKAQEEFRIKKEKEEAAKKRQEEQERKLKEQWE-------EQQ 115
++ER R +E RE+K + + +KE+E ++R++E+ERK +++ E E++
Sbjct: 118 KEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEE 177
Query: 116 RKEREEEEQKRQEKKEKEEALQK 138
RKE+E +E+K++E+ KE ++
Sbjct: 178 RKEKERKERKKRERNRKERKKER 200
Score = 68.6 bits (166), Expect = 1e-11
Identities = 43/161 (26%), Positives = 87/161 (54%), Gaps = 8/161 (4%)
Query: 5 EKMTFPEKPSHKKYRAALKKEKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQLEEEKLL 64
EK E+ +K K+E+ +K+R+ ++ +K ++++ + +E K
Sbjct: 74 EKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKER 133
Query: 65 ERERQRLHEEWLLREQKAQEEFRIKKEKEEAAKKR----QEEQERKLKEQWE----EQQR 116
ER+ +R EE RE+K +E + ++ KE ++R ++E+ERK KE+ E E+ R
Sbjct: 134 ERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNR 193
Query: 117 KEREEEEQKRQEKKEKEEALQKMLDQAENELENGTTWQNPE 157
KER++E ++++ ++ K+E +K + E + + T W+ E
Sbjct: 194 KERKKERERKERRERKKERKKKEERKKERQKDRQTNWREKE 234
Score = 67.0 bits (162), Expect = 4e-11
Identities = 43/139 (30%), Positives = 81/139 (58%), Gaps = 8/139 (5%)
Query: 11 EKPSHKKYRAALKKEKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQLEEEKLLERERQR 70
E + K+ + + E++K+RR+ R R+ +K E ++++ E K ERER++
Sbjct: 44 EIETRKEGKKERESERKKERREREKRKREREKERKRERG----KKEKKGERKKEERERKK 99
Query: 71 LHEEWLLREQKAQEEFRIKKEKEEAAKKRQEEQERKLKEQWEEQQRKEREE---EEQKRQ 127
E +E + +E+ R KKEK+E + +E +ER+ KE+ + ++RKERE E +K +
Sbjct: 100 RRREKENKEGEEKEK-RKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKER 158
Query: 128 EKKEKEEALQKMLDQAENE 146
E+KE+++ +K + + E E
Sbjct: 159 ERKERKKRERKQVGEKEEE 177
Score = 63.2 bits (152), Expect = 5e-10
Identities = 44/139 (31%), Positives = 80/139 (57%), Gaps = 17/139 (12%)
Query: 16 KKYRAALKKEKRKKR-RQELARLRDSGLSQKEEEEDTFIEEQQLEEEKLLERERQRLHEE 74
K+ + +KEKRKK+ ++E R G ++E +E+ EE++ E K ERE++R +E
Sbjct: 104 KENKEGEEKEKRKKKEKKERGRTSKEG-KERERKEERKREERKERERKKEEREKERERKE 162
Query: 75 WLLREQKA---QEEFRIKKEKEEAAKK------------RQEEQERKLKEQWEEQQRKER 119
RE+K +EE R +KE++E K+ R+E +ERK + + +E+++KER
Sbjct: 163 RKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKKEERKKER 222
Query: 120 EEEEQKRQEKKEKEEALQK 138
+++ Q +KE+ + +K
Sbjct: 223 QKDRQTNWREKERGKRERK 241
Score = 63.2 bits (152), Expect = 5e-10
Identities = 33/111 (29%), Positives = 71/111 (63%), Gaps = 1/111 (0%)
Query: 23 KKEKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQLEEEKLLERERQRLHEEWLLREQKA 82
K+E++++ R+E R ++ ++E +E E +Q+ E++ +E++R + R +K
Sbjct: 136 KEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKE 195
Query: 83 QEEFRIKKEKEEAAKKRQEEQERKLKEQWEEQQRKEREEEEQKRQEKKEKE 133
+++ R +KE+ E K+R++++ERK KE+ +++Q RE+E KR+ K+ K+
Sbjct: 196 RKKERERKERRERKKERKKKEERK-KERQKDRQTNWREKERGKRERKERKK 245
Score = 59.7 bits (143), Expect = 6e-09
Identities = 41/133 (30%), Positives = 81/133 (60%), Gaps = 13/133 (9%)
Query: 12 KPSHKKYRAALKKE-KRKKRRQELARLRDSGLSQKEEEEDTFIEEQQLEEEKLLER---- 66
K KK R KE K ++R++E R +K+EE + +E++ +E K ER
Sbjct: 116 KKKEKKERGRTSKEGKERERKEERKREERKERERKKEERE---KERERKERKKRERKQVG 172
Query: 67 ERQRLHEEWLLREQKAQEEFRIKKEKEEAAKKRQE-EQERKLKEQWEEQQRKERE----E 121
E++ +E +E+K +E R +++KE K+R+E ++ERK KE+ +++++K+R+ E
Sbjct: 173 EKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKKEERKKERQKDRQTNWRE 232
Query: 122 EEQKRQEKKEKEE 134
+E+ ++E+KE+++
Sbjct: 233 KERGKRERKERKK 245
Score = 57.4 bits (137), Expect = 3e-08
Identities = 31/121 (25%), Positives = 71/121 (58%), Gaps = 2/121 (1%)
Query: 28 KKRRQELARLRDSGLSQKEEEEDTFIEEQQLEEEKLLERERQRLHEEWLLREQKAQEEFR 87
++R +E+ ++ ++ E + E ++ + E+ ER+R+R +E + ++ +EE
Sbjct: 39 REREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKE--KKGERKKEERE 96
Query: 88 IKKEKEEAAKKRQEEQERKLKEQWEEQQRKEREEEEQKRQEKKEKEEALQKMLDQAENEL 147
KK + E K EE+E++ K++ +E+ R +E +E++R+E++++EE ++ + E E
Sbjct: 97 RKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREK 156
Query: 148 E 148
E
Sbjct: 157 E 157
Score = 55.8 bits (133), Expect = 8e-08
Identities = 35/124 (28%), Positives = 68/124 (54%), Gaps = 7/124 (5%)
Query: 29 KRRQELARLRDSGLSQKEEEEDTFIEEQQLEEEKLLERERQRLHEEWLLR---EQKAQEE 85
+ R+ R G ++E E +E++ E++ ERE++R E E+K +E
Sbjct: 39 REREREIETRKEGKKERESERK---KERREREKRKREREKERKRERGKKEKKGERKKEER 95
Query: 86 FRIKKEKEEAAKKRQEEQERKLKEQWEE-QQRKEREEEEQKRQEKKEKEEALQKMLDQAE 144
R K+ +E+ K+ +E+++RK KE+ E + KE +E E+K + K+E+ + ++ ++ E
Sbjct: 96 ERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEERE 155
Query: 145 NELE 148
E E
Sbjct: 156 KERE 159
Score = 52.4 bits (124), Expect = 9e-07
Identities = 27/124 (21%), Positives = 48/124 (38%)
Query: 359 KNSERRERMGHHDDYYSRLRGRRNPSPDHSYKRNGESERKSSRHRGKKSHKRTSKSRERH 418
+ ER+ G + R + R K N E E K R + +K + + +
Sbjct: 73 REKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKE 132
Query: 419 NSRSRGRNRDRSRDRSRGRGSRSRSRSRSRRSRRSRSQSSSRSRSRGRRRSGNRDRTVQS 478
R R R+ ++R R + R + R R R +R R Q + R + R + ++
Sbjct: 133 RERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERN 192
Query: 479 PKSK 482
K +
Sbjct: 193 RKER 196
Score = 51.2 bits (121), Expect = 2e-06
Identities = 34/130 (26%), Positives = 76/130 (58%), Gaps = 5/130 (3%)
Query: 40 SGLSQKEEEEDTFIEEQQLEEEKLLERERQRLHEEWLLREQKAQEEFRIKKEKEEAAKKR 99
S + ++E E +T ++ ++E+ ER+++R E RE++ +E R + +KE+ +++
Sbjct: 36 SEIREREREIET---RKEGKKERESERKKERREREKRKRERE-KERKRERGKKEKKGERK 91
Query: 100 QEEQERKLKEQWEEQQRKEREEEEQKRQEKKEKEEALQKMLDQAENELENGTTWQNPEPP 159
+EE+ERK K + E++ ++ E+E++K++EKKE+ ++ ++ E + E
Sbjct: 92 KEERERK-KRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERK 150
Query: 160 VDFRVMEKDR 169
+ R E++R
Sbjct: 151 KEEREKERER 160
Score = 46.2 bits (108), Expect = 7e-05
Identities = 28/125 (22%), Positives = 51/125 (40%), Gaps = 2/125 (1%)
Query: 359 KNSERRERMGHHDDYYSRLRGRRNPSPDHSYKRNGESERKSSRHRGKKSHKRTSKSRERH 418
+ RRE+ + + + + + K E ERK R R ++ +R K ER
Sbjct: 97 RKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERK-ERERKKEERE 155
Query: 419 NSRSRGRNRDRSRDRSRGRGSRSRSRSRSRRSRRSRSQSS-SRSRSRGRRRSGNRDRTVQ 477
R R + R R + + + + R R +R R++ + R R RR ++R +
Sbjct: 156 KERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKK 215
Query: 478 SPKSK 482
+ K
Sbjct: 216 EERKK 220
Score = 46.2 bits (108), Expect = 7e-05
Identities = 34/124 (27%), Positives = 53/124 (42%), Gaps = 14/124 (11%)
Query: 355 SSFGKNSERRERMGHHDDYYSRLRGRRNPSPDHSYKRNGESERKSSRHRGKKS---HKRT 411
S GK ER+E R R R +R E ERK + R +K +
Sbjct: 127 SKEGKERERKEE---------RKREERKERERKKEEREKERERKERKKRERKQVGEKEEE 177
Query: 412 SKSRERHNSRSRGRNR-DRSRDRSRGRGSRSRSRSRSRRSRRSRSQSSSRSRSRGRRRSG 470
K +ER + R RNR +R ++R R + R R + R ++ R + + R + + G
Sbjct: 178 RKEKERKERKKRERNRKERKKERER-KERRERKKERKKKEERKKERQKDRQTNWREKERG 236
Query: 471 NRDR 474
R+R
Sbjct: 237 KRER 240
Score = 44.3 bits (103), Expect = 2e-04
Identities = 20/104 (19%), Positives = 46/104 (44%), Gaps = 11/104 (10%)
Query: 390 KRNGESERKSSRHRGKKSHKRTSKSRERHNSRSRGRNRDRSRDRSRGRGSRSRSR----- 444
++ G+ ER+S R + ++ ++ + RE+ R RG+ + + R + R R
Sbjct: 48 RKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKENK 107
Query: 445 ------SRSRRSRRSRSQSSSRSRSRGRRRSGNRDRTVQSPKSK 482
R ++ ++ R ++S + R R+ R+ + + K
Sbjct: 108 EGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKK 151
Score = 44.3 bits (103), Expect = 2e-04
Identities = 30/119 (25%), Positives = 46/119 (38%), Gaps = 3/119 (2%)
Query: 358 GKNSERRERMGHHDDYYSRLRGRRNPSPDHSYKRNGESERKSSR-HRGKKSHKRTSKSRE 416
GK ER + R R R K+ + ERK R K+ ++ +K E
Sbjct: 51 GKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKENKEGE 110
Query: 417 RHNSRSRGRNRDRSRDRSRGRGSRSRSRSRSRRSRRSRS-QSSSRSRSRGRRRSGNRDR 474
R + ++R R G+ R R R R R+ R + R + R R+ R+R
Sbjct: 111 EKEKRKKKEKKERGRTSKEGK-ERERKEERKREERKERERKKEEREKERERKERKKRER 168
Score = 43.9 bits (102), Expect = 3e-04
Identities = 24/94 (25%), Positives = 41/94 (43%), Gaps = 5/94 (5%)
Query: 394 ESERKSSRHRGKKSHKRTSKSRERHNSRSRGRNRDRSRDRSRG----RGSRSR-SRSRSR 448
E ER+ + K + + + +ER R R R++ R R RG +G R + R R +
Sbjct: 40 EREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKK 99
Query: 449 RSRRSRSQSSSRSRSRGRRRSGNRDRTVQSPKSK 482
R R ++ R ++ R RT + K +
Sbjct: 100 RRREKENKEGEEKEKRKKKEKKERGRTSKEGKER 133
Score = 43.1 bits (100), Expect = 6e-04
Identities = 22/118 (18%), Positives = 47/118 (39%), Gaps = 3/118 (2%)
Query: 358 GKNSERRERMGHHDDYYSRLRGRRNPSPDHSYKRNGESERKSSRHRGKKSHKRTSKSRER 417
G+ E+R++ + + G+ + + + + R K+ ++ K RER
Sbjct: 109 GEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERKERKKRER 168
Query: 418 H---NSRSRGRNRDRSRDRSRGRGSRSRSRSRSRRSRRSRSQSSSRSRSRGRRRSGNR 472
+ ++R + R R + R + R R+ RR R + + R + R +R
Sbjct: 169 KQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKKEERKKERQKDR 226
Score = 41.2 bits (95), Expect = 0.002
Identities = 16/64 (25%), Positives = 44/64 (68%)
Query: 83 QEEFRIKKEKEEAAKKRQEEQERKLKEQWEEQQRKEREEEEQKRQEKKEKEEALQKMLDQ 142
Q E R ++ + E K+ ++E+E + K++ E+++++RE E+++++E+ +KE+ ++ ++
Sbjct: 35 QSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEE 94
Query: 143 AENE 146
E +
Sbjct: 95 RERK 98
Score = 36.6 bits (83), Expect = 0.052
Identities = 17/60 (28%), Positives = 41/60 (68%), Gaps = 2/60 (3%)
Query: 79 EQKAQEEFRIKKEKEEAAKKRQEEQERKLKEQWEEQQRKEREEEEQKRQEKKEKEEALQK 138
+ + +E R + ++E K+R+ E++++ +E+ E++++ERE+E ++ + KKEK+ +K
Sbjct: 35 QSEIREREREIETRKEGKKERESERKKERRER--EKRKREREKERKRERGKKEKKGERKK 92
Score = 33.1 bits (74), Expect = 0.58
Identities = 17/68 (25%), Positives = 30/68 (44%), Gaps = 5/68 (7%)
Query: 401 RHRGKKSHKRTSKSRERHNSRSRGRNRDRSRDRSRGRGSRSRSRSRSRRSRRSRSQSSSR 460
R R ++ R +ER + R + R R+R + + R + R R R + + +
Sbjct: 39 REREREIETRKEGKKERESERKKER-----REREKRKREREKERKRERGKKEKKGERKKE 93
Query: 461 SRSRGRRR 468
R R +RR
Sbjct: 94 ERERKKRR 101
>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 73.2 bits (178), Expect = 5e-13
Identities = 47/165 (28%), Positives = 95/165 (57%), Gaps = 17/165 (10%)
Query: 5 EKMTFPEKPSHKKYRAALKKEKRKKRRQELARLRDSGLSQKEE----------EEDTFIE 54
EKM E+ H++ ++E + R++E R ++ + ++EE E+D I+
Sbjct: 325 EKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQ 384
Query: 55 EQQLE----EEKLLERERQRLHEEWLLREQKAQEEFRIKKEKEEAAKKRQEEQERKLKEQ 110
EQ+ E EEK+ E+E +R + W ++ +++ +I++++EE RQEE+ R+L+E
Sbjct: 385 EQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMW--RQEEKIRELEEM 442
Query: 111 WEEQQRKEREEEEQKRQEKKEKEEALQKMLDQAEN-ELENGTTWQ 154
++Q+ K RE EE+ ++E+++ +E +K+ Q E + + TW+
Sbjct: 443 MQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWR 487
Score = 65.5 bits (158), Expect = 1e-10
Identities = 43/148 (29%), Positives = 86/148 (58%), Gaps = 7/148 (4%)
Query: 26 KRKKRRQELARLRDSGLSQKEEEEDTFIEEQQL--EEEKLLERERQRLHEEWLLREQKAQ 83
+ +K +++ ++ + L +E+EE + +E+++ +EEK+ E+E + +E +REQ +
Sbjct: 302 QEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQ--E 359
Query: 84 EEFRIKKEKEEAAKKRQEEQERKLKEQWEEQQRKERE--EEEQKRQEKKEKEEALQKMLD 141
E+ R ++EK +++ EQ+ K++EQ EE R+E + E+E+KRQEK ++E + D
Sbjct: 360 EKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQD 419
Query: 142 QAENELENGTTWQNPEPPVDFRVMEKDR 169
+ E E W+ E + M +D+
Sbjct: 420 EKIREQEE-EMWRQEEKIRELEEMMQDQ 446
Score = 65.1 bits (157), Expect = 1e-10
Identities = 55/210 (26%), Positives = 101/210 (48%), Gaps = 9/210 (4%)
Query: 16 KKYRAALKKEKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQLEEEKLLERERQRLHEEW 75
K+ ++EK+ + + E R ++ + ++EE+ E Q +EEKL E E + EE
Sbjct: 403 KRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEE 462
Query: 76 LLREQKAQEEFRIKKEKEEAAKKRQEEQERKLKEQ---WEEQQRKEREEEEQKRQEKKEK 132
++EQ +E+ + ++EK + +++ QE+ LK++ WE++++ R+EE+ QE+K +
Sbjct: 463 KMQEQ--EEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQ 520
Query: 133 EEALQKMLDQAENELENGT-TWQNPE--PPVDFRVMEKDRANCPFYSKTGACRFGDRCSR 189
E+ +KM Q E E WQ E + R+ E + K R S
Sbjct: 521 EQE-EKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRESG 579
Query: 190 KHNFPTSSPTLLIKSMFTTFGMEQCRRDDY 219
PT +P L ++ Q ++D Y
Sbjct: 580 SQRLPTLTPILQVELKSQEAQSLQQQQDHY 609
Score = 63.9 bits (154), Expect = 3e-10
Identities = 40/146 (27%), Positives = 88/146 (60%), Gaps = 5/146 (3%)
Query: 5 EKMTFPEKPSHKKYRAALKKEKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQLEEEKLL 64
EKM EK ++ ++E+ R++E R + + +EE+ E+ Q EEEK+
Sbjct: 406 EKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQ 465
Query: 65 ERERQRLHEEWLLREQKAQEEFRIKK--EKEEAAKKRQEEQERKLKEQWEEQQRKEREEE 122
E+E + +E ++EQ+ ++ +R +K ++EE +++E+ R+ ++ WE++++ + +EE
Sbjct: 466 EQEEKIQRQEEKIQEQE-EKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEE 524
Query: 123 EQKRQEKKEKEEALQKMLDQAENELE 148
+ +RQE+K +E+ ++ L Q E +++
Sbjct: 525 KMQRQEEKMREQEVR--LWQQEEKMQ 548
Score = 58.9 bits (141), Expect = 1e-08
Identities = 38/134 (28%), Positives = 80/134 (59%), Gaps = 11/134 (8%)
Query: 22 LKKEKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQL--EEEKLLERERQRLHEEWLLRE 79
+++++ K RQE ++ + +E+E+ + +E+++ +EEK+ E+E + +E +RE
Sbjct: 320 IREQEEKMWRQE-EKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIRE 378
Query: 80 Q------KAQEEFRIKKEKEEAAKKRQEEQERKLKEQWEEQQRKEREEEEQKRQEKKEKE 133
Q + +E +R +++ E +KRQE+ R+ K+ E+ ++ +EEE RQE+K +E
Sbjct: 379 QDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRE 438
Query: 134 EALQKMLDQAENEL 147
L++M+ E +L
Sbjct: 439 --LEEMMQDQEEKL 450
Score = 51.2 bits (121), Expect = 2e-06
Identities = 37/136 (27%), Positives = 81/136 (59%), Gaps = 9/136 (6%)
Query: 42 LSQKEEEEDTFIEEQ-QLEEEKLLERE---RQRLHEEWLLREQKAQEEFRIKKEKEEAAK 97
L+Q++EE+ EE+ Q +EEK+ E+E R++ + W E+ ++E +I++++++ +
Sbjct: 291 LNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWR 350
Query: 98 KRQE--EQERKLKEQWEEQQRKERE--EEEQKRQEKKEKE-EALQKMLDQAENELENGTT 152
+ ++ EQE K++EQ E+ R+E + E+++K QE++E+ +K+ +Q E E
Sbjct: 351 QEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWR 410
Query: 153 WQNPEPPVDFRVMEKD 168
+ D ++ E++
Sbjct: 411 QEKKMREQDEKIREQE 426
Score = 50.1 bits (118), Expect = 5e-06
Identities = 50/176 (28%), Positives = 86/176 (48%), Gaps = 37/176 (21%)
Query: 5 EKMTFP-EKPSHKKYRAALKKEKRKKRRQELA-------------RLRDSGLSQKEEEED 50
EK+T + PS + YR + E+ K++ EL +L L +K E
Sbjct: 193 EKLTKERDAPSLELYRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQ 252
Query: 51 TFIEEQQLE-EEKLLERERQRL----------HEEWLLREQKAQEEFRIKKEKEEAAKKR 99
+ +QQL+ E L +E Q + +E W L Q+ +E+ ++EK + +++
Sbjct: 253 LLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEK 312
Query: 100 QEEQERKLKEQWE----------EQQRKEREEEEQK-RQEKKEKEEALQKMLDQAE 144
EQE K++EQ E EQ+ K RE+E++ RQE+K +E+ +K+ +Q E
Sbjct: 313 MCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQE-EKIREQEE 367
Score = 49.7 bits (117), Expect = 6e-06
Identities = 39/140 (27%), Positives = 76/140 (54%), Gaps = 10/140 (7%)
Query: 5 EKMTFPEKPSHKKYRAALKKEKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQLEEEKLL 64
E+M ++ ++ +++E+ K + QE R Q++EE+ E+ +EEK+
Sbjct: 440 EEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIW 499
Query: 65 ERERQRLHEEWLLREQKAQEEFRIKKEKEEAAKKRQEEQERKLKEQWEEQQRKEREEEEQ 124
E+E + +E + EQ +E+ + ++EK + +++ EQE +L W QQ ++ +E+E
Sbjct: 500 EQEEKMWRQEEKMWEQ--EEKMQEQEEKMQRQEEKMREQEVRL---W--QQEEKMQEQEV 552
Query: 125 KRQEKKEKEEALQKMLDQAE 144
+ Q E EE L K+ +AE
Sbjct: 553 RLQ---ELEERLGKLGQKAE 569
Score = 47.4 bits (111), Expect = 3e-05
Identities = 35/112 (31%), Positives = 66/112 (58%), Gaps = 14/112 (12%)
Query: 43 SQKEEEEDTFIEEQQLEE------EKLLERERQRLHEEWLLREQKAQEEFRIKKEKEEAA 96
+Q EE E + QQ EE EK+ E+E + +E +REQ+ + + +K E+
Sbjct: 280 AQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEE 339
Query: 97 KKRQEE-----QERKLKEQWEEQQRKEREEEEQKRQEK-KEKEEALQKMLDQ 142
K R++E QE K++EQ E++ +E+EE+ +++EK +E++E +Q+ ++
Sbjct: 340 KIREQEDKMWRQEEKIREQ--EEKIREQEEKMWRQEEKIREQDEKIQEQEEE 389
Score = 40.8 bits (94), Expect = 0.003
Identities = 39/163 (23%), Positives = 80/163 (49%), Gaps = 22/163 (13%)
Query: 5 EKMTFPEKPSHKKYRAALKKEKRKKRRQELARLRDSGLSQKE----EEEDTFIEEQQL-- 58
EKM E+ ++ ++E++ + ++E ++ L Q+E +EE + +E+++
Sbjct: 455 EKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWE 514
Query: 59 EEEKLLERERQRLHEEWLLREQKA----QEEFRIKKEKEEAAKKRQEEQERKLKEQWEEQ 114
+EEK+ E+E + +E +REQ+ QEE K +++E + EE+ KL ++ E
Sbjct: 515 QEEKMQEQEEKMQRQEEKMREQEVRLWQQEE---KMQEQEVRLQELEERLGKLGQKAELL 571
Query: 115 QRKEREEEEQKR---------QEKKEKEEALQKMLDQAENELE 148
RE Q+ + K ++ ++LQ+ D L+
Sbjct: 572 GGAGRESGSQRLPTLTPILQVELKSQEAQSLQQQQDHYRGHLQ 614
Score = 29.6 bits (65), Expect = 6.4
Identities = 24/134 (17%), Positives = 60/134 (44%)
Query: 17 KYRAALKKEKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQLEEEKLLERERQRLHEEWL 76
K + +++ K RQE Q++EE+ EE+ E+E L ++ +++ E+ +
Sbjct: 493 KQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEV 552
Query: 77 LREQKAQEEFRIKKEKEEAAKKRQEEQERKLKEQWEEQQRKEREEEEQKRQEKKEKEEAL 136
++ + ++ ++ E +E ++L Q + + +E Q Q++++
Sbjct: 553 RLQELEERLGKLGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQSLQQQQDHYRGH 612
Query: 137 QKMLDQAENELENG 150
+ A +L +G
Sbjct: 613 LQQYVAAYQQLASG 626
>gi|239745127 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 73.2 bits (178), Expect = 5e-13
Identities = 47/165 (28%), Positives = 95/165 (57%), Gaps = 17/165 (10%)
Query: 5 EKMTFPEKPSHKKYRAALKKEKRKKRRQELARLRDSGLSQKEE----------EEDTFIE 54
EKM E+ H++ ++E + R++E R ++ + ++EE E+D I+
Sbjct: 325 EKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQ 384
Query: 55 EQQLE----EEKLLERERQRLHEEWLLREQKAQEEFRIKKEKEEAAKKRQEEQERKLKEQ 110
EQ+ E EEK+ E+E +R + W ++ +++ +I++++EE RQEE+ R+L+E
Sbjct: 385 EQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMW--RQEEKIRELEEM 442
Query: 111 WEEQQRKEREEEEQKRQEKKEKEEALQKMLDQAEN-ELENGTTWQ 154
++Q+ K RE EE+ ++E+++ +E +K+ Q E + + TW+
Sbjct: 443 MQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWR 487
Score = 65.5 bits (158), Expect = 1e-10
Identities = 43/148 (29%), Positives = 86/148 (58%), Gaps = 7/148 (4%)
Query: 26 KRKKRRQELARLRDSGLSQKEEEEDTFIEEQQL--EEEKLLERERQRLHEEWLLREQKAQ 83
+ +K +++ ++ + L +E+EE + +E+++ +EEK+ E+E + +E +REQ +
Sbjct: 302 QEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQ--E 359
Query: 84 EEFRIKKEKEEAAKKRQEEQERKLKEQWEEQQRKERE--EEEQKRQEKKEKEEALQKMLD 141
E+ R ++EK +++ EQ+ K++EQ EE R+E + E+E+KRQEK ++E + D
Sbjct: 360 EKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQD 419
Query: 142 QAENELENGTTWQNPEPPVDFRVMEKDR 169
+ E E W+ E + M +D+
Sbjct: 420 EKIREQEE-EMWRQEEKIRELEEMMQDQ 446
Score = 65.1 bits (157), Expect = 1e-10
Identities = 55/210 (26%), Positives = 101/210 (48%), Gaps = 9/210 (4%)
Query: 16 KKYRAALKKEKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQLEEEKLLERERQRLHEEW 75
K+ ++EK+ + + E R ++ + ++EE+ E Q +EEKL E E + EE
Sbjct: 403 KRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEE 462
Query: 76 LLREQKAQEEFRIKKEKEEAAKKRQEEQERKLKEQ---WEEQQRKEREEEEQKRQEKKEK 132
++EQ +E+ + ++EK + +++ QE+ LK++ WE++++ R+EE+ QE+K +
Sbjct: 463 KMQEQ--EEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQ 520
Query: 133 EEALQKMLDQAENELENGT-TWQNPE--PPVDFRVMEKDRANCPFYSKTGACRFGDRCSR 189
E+ +KM Q E E WQ E + R+ E + K R S
Sbjct: 521 EQE-EKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRESG 579
Query: 190 KHNFPTSSPTLLIKSMFTTFGMEQCRRDDY 219
PT +P L ++ Q ++D Y
Sbjct: 580 SQRLPTLTPILQVELKSQEAQSLQQQQDHY 609
Score = 63.9 bits (154), Expect = 3e-10
Identities = 40/146 (27%), Positives = 88/146 (60%), Gaps = 5/146 (3%)
Query: 5 EKMTFPEKPSHKKYRAALKKEKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQLEEEKLL 64
EKM EK ++ ++E+ R++E R + + +EE+ E+ Q EEEK+
Sbjct: 406 EKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQ 465
Query: 65 ERERQRLHEEWLLREQKAQEEFRIKK--EKEEAAKKRQEEQERKLKEQWEEQQRKEREEE 122
E+E + +E ++EQ+ ++ +R +K ++EE +++E+ R+ ++ WE++++ + +EE
Sbjct: 466 EQEEKIQRQEEKIQEQE-EKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEE 524
Query: 123 EQKRQEKKEKEEALQKMLDQAENELE 148
+ +RQE+K +E+ ++ L Q E +++
Sbjct: 525 KMQRQEEKMREQEVR--LWQQEEKMQ 548
Score = 58.9 bits (141), Expect = 1e-08
Identities = 38/134 (28%), Positives = 80/134 (59%), Gaps = 11/134 (8%)
Query: 22 LKKEKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQL--EEEKLLERERQRLHEEWLLRE 79
+++++ K RQE ++ + +E+E+ + +E+++ +EEK+ E+E + +E +RE
Sbjct: 320 IREQEEKMWRQE-EKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQEEKMWRQEEKIRE 378
Query: 80 Q------KAQEEFRIKKEKEEAAKKRQEEQERKLKEQWEEQQRKEREEEEQKRQEKKEKE 133
Q + +E +R +++ E +KRQE+ R+ K+ E+ ++ +EEE RQE+K +E
Sbjct: 379 QDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRE 438
Query: 134 EALQKMLDQAENEL 147
L++M+ E +L
Sbjct: 439 --LEEMMQDQEEKL 450
Score = 51.2 bits (121), Expect = 2e-06
Identities = 37/136 (27%), Positives = 81/136 (59%), Gaps = 9/136 (6%)
Query: 42 LSQKEEEEDTFIEEQ-QLEEEKLLERE---RQRLHEEWLLREQKAQEEFRIKKEKEEAAK 97
L+Q++EE+ EE+ Q +EEK+ E+E R++ + W E+ ++E +I++++++ +
Sbjct: 291 LNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWR 350
Query: 98 KRQE--EQERKLKEQWEEQQRKERE--EEEQKRQEKKEKE-EALQKMLDQAENELENGTT 152
+ ++ EQE K++EQ E+ R+E + E+++K QE++E+ +K+ +Q E E
Sbjct: 351 QEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWR 410
Query: 153 WQNPEPPVDFRVMEKD 168
+ D ++ E++
Sbjct: 411 QEKKMREQDEKIREQE 426
Score = 49.7 bits (117), Expect = 6e-06
Identities = 39/140 (27%), Positives = 76/140 (54%), Gaps = 10/140 (7%)
Query: 5 EKMTFPEKPSHKKYRAALKKEKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQLEEEKLL 64
E+M ++ ++ +++E+ K + QE R Q++EE+ E+ +EEK+
Sbjct: 440 EEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIW 499
Query: 65 ERERQRLHEEWLLREQKAQEEFRIKKEKEEAAKKRQEEQERKLKEQWEEQQRKEREEEEQ 124
E+E + +E + EQ +E+ + ++EK + +++ EQE +L W QQ ++ +E+E
Sbjct: 500 EQEEKMWRQEEKMWEQ--EEKMQEQEEKMQRQEEKMREQEVRL---W--QQEEKMQEQEV 552
Query: 125 KRQEKKEKEEALQKMLDQAE 144
+ Q E EE L K+ +AE
Sbjct: 553 RLQ---ELEERLGKLGQKAE 569
Score = 47.4 bits (111), Expect = 3e-05
Identities = 35/112 (31%), Positives = 66/112 (58%), Gaps = 14/112 (12%)
Query: 43 SQKEEEEDTFIEEQQLEE------EKLLERERQRLHEEWLLREQKAQEEFRIKKEKEEAA 96
+Q EE E + QQ EE EK+ E+E + +E +REQ+ + + +K E+
Sbjct: 280 AQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEE 339
Query: 97 KKRQEE-----QERKLKEQWEEQQRKEREEEEQKRQEK-KEKEEALQKMLDQ 142
K R++E QE K++EQ E++ +E+EE+ +++EK +E++E +Q+ ++
Sbjct: 340 KIREQEDKMWRQEEKIREQ--EEKIREQEEKMWRQEEKIREQDEKIQEQEEE 389
Score = 46.6 bits (109), Expect = 5e-05
Identities = 45/162 (27%), Positives = 78/162 (48%), Gaps = 36/162 (22%)
Query: 18 YRAALKKEKRKKRRQELA-------------RLRDSGLSQKEEEEDTFIEEQQLE-EEKL 63
YR + E+ K++ EL +L L +K E + +QQL+ E
Sbjct: 207 YRNTITDEELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADR 266
Query: 64 LERERQRL----------HEEWLLREQKAQEEFRIKKEKEEAAKKRQEEQERKLKEQWE- 112
L +E Q + +E W L Q+ +E+ ++EK + +++ EQE K++EQ E
Sbjct: 267 LGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEK 326
Query: 113 ---------EQQRKEREEEEQK-RQEKKEKEEALQKMLDQAE 144
EQ+ K RE+E++ RQE+K +E+ +K+ +Q E
Sbjct: 327 MWRQEEKMHEQEEKIREQEDKMWRQEEKIREQE-EKIREQEE 367
Score = 40.8 bits (94), Expect = 0.003
Identities = 39/163 (23%), Positives = 80/163 (49%), Gaps = 22/163 (13%)
Query: 5 EKMTFPEKPSHKKYRAALKKEKRKKRRQELARLRDSGLSQKE----EEEDTFIEEQQL-- 58
EKM E+ ++ ++E++ + ++E ++ L Q+E +EE + +E+++
Sbjct: 455 EKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWE 514
Query: 59 EEEKLLERERQRLHEEWLLREQKA----QEEFRIKKEKEEAAKKRQEEQERKLKEQWEEQ 114
+EEK+ E+E + +E +REQ+ QEE K +++E + EE+ KL ++ E
Sbjct: 515 QEEKMQEQEEKMQRQEEKMREQEVRLWQQEE---KMQEQEVRLQELEERLGKLGQKAELL 571
Query: 115 QRKEREEEEQKR---------QEKKEKEEALQKMLDQAENELE 148
RE Q+ + K ++ ++LQ+ D L+
Sbjct: 572 GGAGRESGSQRLPTLTPILQVELKSQEAQSLQQQQDHYRGHLQ 614
Score = 29.6 bits (65), Expect = 6.4
Identities = 24/134 (17%), Positives = 60/134 (44%)
Query: 17 KYRAALKKEKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQLEEEKLLERERQRLHEEWL 76
K + +++ K RQE Q++EE+ EE+ E+E L ++ +++ E+ +
Sbjct: 493 KQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEV 552
Query: 77 LREQKAQEEFRIKKEKEEAAKKRQEEQERKLKEQWEEQQRKEREEEEQKRQEKKEKEEAL 136
++ + ++ ++ E +E ++L Q + + +E Q Q++++
Sbjct: 553 RLQELEERLGKLGQKAELLGGAGRESGSQRLPTLTPILQVELKSQEAQSLQQQQDHYRGH 612
Query: 137 QKMLDQAENELENG 150
+ A +L +G
Sbjct: 613 LQQYVAAYQQLASG 626
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 73.2 bits (178), Expect = 5e-13
Identities = 49/145 (33%), Positives = 88/145 (60%), Gaps = 11/145 (7%)
Query: 11 EKPSHKKYRAALKKEKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQLEEEKLLE-RERQ 69
E+ +K L+KE+ K + +E R R+ Q+EEE+ +E Q+L E+ E +++Q
Sbjct: 242 EEKEWRKRETVLRKEEEKLQEEEPQRQREL---QEEEEQLRKLERQELRRERQEEEQQQQ 298
Query: 70 RLHEEWLLREQKA------QEEFRIKKEKEEAAKKRQEEQERKLKEQWEEQQ-RKEREEE 122
RL E LR ++ QEE R ++E+ E ++R+E+Q R+ +E+ EQQ R+E+EEE
Sbjct: 299 RLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEE 358
Query: 123 EQKRQEKKEKEEALQKMLDQAENEL 147
+++Q ++E+EE ++ + E +L
Sbjct: 359 RREQQLRREQEEERREQQLRREQQL 383
Score = 73.2 bits (178), Expect = 5e-13
Identities = 50/140 (35%), Positives = 82/140 (58%), Gaps = 15/140 (10%)
Query: 5 EKMTFPEKPSHKKYRAALKKEKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQLEEEKLL 64
E+ E+ ++ L++E K+RRQE R Q EEE+ EE+QL E+
Sbjct: 1077 ERQYRKEEELQQEEEQLLREEPEKRRRQERER-------QCREEEELQQEEEQLLREERE 1129
Query: 65 ERERQRLHEEWLLREQKAQEEFRIKKEKEEAAKKRQEEQERKLKEQWEEQQRKE---REE 121
+R RQ L ++ E+ QEE ++ +E+ E K+R++E ER+ +E+ E QQ +E REE
Sbjct: 1130 KRRRQELERQYREEEEVQQEEEQLLREEPE--KRRRQELERQYREEEELQQEEEQLLREE 1187
Query: 122 EEQKRQEKK---EKEEALQK 138
+E++RQE++ +EE LQ+
Sbjct: 1188 QEKRRQERERQYREEEELQR 1207
Score = 72.8 bits (177), Expect = 7e-13
Identities = 52/167 (31%), Positives = 94/167 (56%), Gaps = 24/167 (14%)
Query: 5 EKMTFPEKPSHKKYRAALKKEKRKKRRQELARL--RDSGLSQKEEE-------------- 48
EK E+ ++ L++E+ K+RRQE R + L Q+EE+
Sbjct: 987 EKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQER 1046
Query: 49 EDTFIEEQQL--EEEKLLERERQRLHEEWLLREQKAQEEFRIKKE---KEEAAKKRQEEQ 103
E + EE++L EEE+LL ER+ + L R+ + +EE + ++E +EE K+R++E+
Sbjct: 1047 ERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQER 1106
Query: 104 ERKLKEQWEEQQRKE---REEEEQKRQEKKEKEEALQKMLDQAENEL 147
ER+ +E+ E QQ +E REE E++R+++ E++ ++ + Q E +L
Sbjct: 1107 ERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQL 1153
Score = 71.6 bits (174), Expect = 1e-12
Identities = 48/140 (34%), Positives = 81/140 (57%), Gaps = 17/140 (12%)
Query: 5 EKMTFPEKPSHKKYRAALKKEKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQLEEEKLL 64
E+ E+ ++ L++E+ K+RRQEL R Q EEE+ EE+QL E+
Sbjct: 1107 ERQCREEEELQQEEEQLLREEREKRRRQELER-------QYREEEEVQQEEEQLLREEPE 1159
Query: 65 ERERQRLHEEWLLREQKAQEEFRIKKEKEEAAKKRQEEQERKLKEQWE--EQQRKEREEE 122
+R RQ L ++ E+ QEE ++ +E++E KR++E+ER+ +E+ E Q+RK+R +
Sbjct: 1160 KRRRQELERQYREEEELQQEEEQLLREEQE---KRRQERERQYREEEELQRQKRKQRYRD 1216
Query: 123 EQKRQEKK-----EKEEALQ 137
E +R + K EKE A++
Sbjct: 1217 EDQRSDLKWQWEPEKENAVR 1236
Score = 71.2 bits (173), Expect = 2e-12
Identities = 43/141 (30%), Positives = 81/141 (57%), Gaps = 11/141 (7%)
Query: 11 EKPSHKKYRAALKKEKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQLEEEKLLERERQR 70
E+ ++ + ++++ ++R Q+L R Q+ E EQQL E+ L RE+Q
Sbjct: 354 EQEEERREQQLRREQEEERREQQLRR------EQQLRREQQLRREQQLRREQQLRREQQL 407
Query: 71 LHEEWLLREQKAQEEFRIKKEKEEAAKKRQEEQER---KLKEQWEEQQRKEREEEEQKRQ 127
E+ L REQ+ + E ++++E+EE +++ EQER +LK + EE++ + EEE +R
Sbjct: 408 RREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERH 467
Query: 128 EKKEKEEALQKMLDQAENELE 148
E++ +++ L++ DQ E E
Sbjct: 468 EQERRKQQLKR--DQEEERRE 486
Score = 70.5 bits (171), Expect = 3e-12
Identities = 36/124 (29%), Positives = 82/124 (66%), Gaps = 7/124 (5%)
Query: 23 KKEKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQLEEEKLLERERQRLHEEWLLREQKA 82
++EK ++R+ + R + L ++E + ++E EEE+L + ERQ L E R+++
Sbjct: 241 EEEKEWRKRETVLRKEEEKLQEEEPQRQRELQE---EEEQLRKLERQELRRE---RQEEE 294
Query: 83 QEEFRIKKEKEEAAKKRQEEQERKLKEQWEEQQRKEREEEEQKRQEKKEKEEALQKMLDQ 142
Q++ R+++E ++ +K++EE+ + +E+ E+Q+R+E++EE +++Q ++E+EE ++ L +
Sbjct: 295 QQQQRLRRE-QQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRR 353
Query: 143 AENE 146
+ E
Sbjct: 354 EQEE 357
Score = 69.7 bits (169), Expect = 6e-12
Identities = 39/128 (30%), Positives = 80/128 (62%), Gaps = 9/128 (7%)
Query: 22 LKKEKRKKRRQELAR-----LRDSGLSQKEEEEDTFIEEQQLEEEKLLERERQRLHEEWL 76
L++E+ ++R Q+L R R+ L +++EEE EQQL E+ L RE+Q E+ L
Sbjct: 339 LRREQEERREQQLRREQEEERREQQLRREQEEER---REQQLRREQQLRREQQLRREQQL 395
Query: 77 LREQKAQEEFRIKKEKEEAAKKRQEEQERKLKEQWEEQQRKEREEEEQKRQEKKEKEEAL 136
REQ+ + E ++++E ++ +++Q +E++L+ + EE++ +++ E+E++ Q K ++E
Sbjct: 396 RREQQLRREQQLRRE-QQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEER 454
Query: 137 QKMLDQAE 144
+ L + E
Sbjct: 455 RDWLKREE 462
Score = 69.7 bits (169), Expect = 6e-12
Identities = 41/136 (30%), Positives = 86/136 (63%), Gaps = 14/136 (10%)
Query: 22 LKKEKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQLEEEKLLERERQRLHEEWLLREQK 81
L++E++ +R Q+L R + Q+EE + E+++ E+ E+E +R +WL RE++
Sbjct: 407 LRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERR---DWLKREEE 463
Query: 82 AQ------EEFRIKKEKEEAAKKR----QEEQERKLKEQWEEQQRKEREEEEQKRQEKKE 131
+ + ++K+++EE ++R +EE+ R+ +E+ E+Q R+E+EE ++R +++E
Sbjct: 464 TERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQE 523
Query: 132 KEEALQKMLDQAENEL 147
+EE LQ+ L ++E +L
Sbjct: 524 EEERLQQRL-RSEQQL 538
Score = 69.7 bits (169), Expect = 6e-12
Identities = 39/136 (28%), Positives = 83/136 (61%), Gaps = 5/136 (3%)
Query: 12 KPSHKKYRAALKKEKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQLEEEKLLERERQRL 71
K ++ R LK+E+ +R ++ R + Q+EE + +++ LEEE+ RE+Q
Sbjct: 448 KREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLK---LEEEE--RREQQER 502
Query: 72 HEEWLLREQKAQEEFRIKKEKEEAAKKRQEEQERKLKEQWEEQQRKEREEEEQKRQEKKE 131
E+ L REQ+ + E R+K+++EE +++ E++L+ + EE++ + + EE+KR E++
Sbjct: 503 REQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQER 562
Query: 132 KEEALQKMLDQAENEL 147
+E+ L++ ++ ++L
Sbjct: 563 REQRLKREQEERRDQL 578
Score = 69.7 bits (169), Expect = 6e-12
Identities = 44/140 (31%), Positives = 86/140 (61%), Gaps = 14/140 (10%)
Query: 16 KKYRAALKKEKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQL--EEEKLLERERQRLHE 73
+K + L++E+ + +R+E + R ++E+E + EE+QL EEE+LL ER++
Sbjct: 900 RKEQQLLQEEEEELQREEREKRR------RQEQERQYREEEQLQQEEEQLLREEREKRRR 953
Query: 74 EWLLREQKAQEEFRIKKEK---EEAAKKRQEEQERKLKEQWEEQQRKE---REEEEQKRQ 127
+ R+ + ++ + K+E+ EE K+R++E+E+K +E+ E QQ +E REE E++R+
Sbjct: 954 QERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRR 1013
Query: 128 EKKEKEEALQKMLDQAENEL 147
++ E++ + L Q E +L
Sbjct: 1014 QEWERQYRKKDELQQEEEQL 1033
Score = 68.9 bits (167), Expect = 9e-12
Identities = 36/130 (27%), Positives = 84/130 (64%), Gaps = 3/130 (2%)
Query: 11 EKPSHKKYRAALKKEKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQLEEEKLLERERQR 70
E+ K R L++E++++ +Q+ R+ L +K+EEE +E++ E+++ E++ +R
Sbjct: 275 EEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEER 334
Query: 71 LHEEWLLREQKAQEEFRIKKEKEEAAKKRQ--EEQERKLKEQWEEQQRKEREEEEQKRQE 128
E+ L REQ+ + E ++++E+EE +++Q EQE + +EQ ++++ R E++ +R++
Sbjct: 335 -REQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQ 393
Query: 129 KKEKEEALQK 138
+ +E+ L++
Sbjct: 394 QLRREQQLRR 403
Score = 68.9 bits (167), Expect = 9e-12
Identities = 44/142 (30%), Positives = 80/142 (56%), Gaps = 18/142 (12%)
Query: 23 KKEKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQLEEEKLLERERQRLHEEWLLREQKA 82
++E++ +R Q+L R + Q+ E EQQL E+ L RE+Q E+ L REQ+
Sbjct: 372 RREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEE 431
Query: 83 QE----------EFRIKKEKEEAAK--KRQEEQERKLKEQWEEQQRKEREEEEQKR---- 126
+ E R+K+E+EE KR+EE ER +E+ ++Q ++++EEE ++R
Sbjct: 432 ERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKL 491
Query: 127 --QEKKEKEEALQKMLDQAENE 146
+E++E++E ++ L + + E
Sbjct: 492 EEEERREQQERREQQLRREQEE 513
Score = 68.9 bits (167), Expect = 9e-12
Identities = 47/146 (32%), Positives = 82/146 (56%), Gaps = 12/146 (8%)
Query: 5 EKMTFPEKPSHKKYRAALKKEKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQLEEEKLL 64
E+ E+ ++ L +E+ +RRQEL R Q +EE+ EE+QL E+
Sbjct: 1047 ERQYREEEELQQEEEQLLGEERETRRRQELER-------QYRKEEELQQEEEQLLREEPE 1099
Query: 65 ERERQRLHEEWLLREQKAQEEFRIKKEKEEAAKKRQEEQERKLKEQWEEQQRKE---REE 121
+R RQ + E+ QEE ++ +E+ E K+R++E ER+ +E+ E QQ +E REE
Sbjct: 1100 KRRRQERERQCREEEELQQEEEQLLREERE--KRRRQELERQYREEEEVQQEEEQLLREE 1157
Query: 122 EEQKRQEKKEKEEALQKMLDQAENEL 147
E++R+++ E++ ++ L Q E +L
Sbjct: 1158 PEKRRRQELERQYREEEELQQEEEQL 1183
Score = 68.6 bits (166), Expect = 1e-11
Identities = 41/130 (31%), Positives = 81/130 (62%), Gaps = 7/130 (5%)
Query: 22 LKKEKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQLEEEKLLERERQRLHEEWLLREQK 81
L++E+ ++R Q L R + L Q E E EQ+ ++LL+RE +R ++ L REQ+
Sbjct: 538 LRREQEERREQLLKREEEKRLEQ-ERREQRLKREQEERRDQLLKREEER-RQQRLKREQE 595
Query: 82 AQEEFRIKKEKEEAAKKRQEEQERKLKEQWEEQQRKE---REEEEQKRQE--KKEKEEAL 136
+ E R+K+E+ E ++ + ++R +E+ EE++R++ EE+E++RQ+ ++E++E
Sbjct: 596 ERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERR 655
Query: 137 QKMLDQAENE 146
++ L + E E
Sbjct: 656 EQRLKREEEE 665
Score = 68.6 bits (166), Expect = 1e-11
Identities = 45/146 (30%), Positives = 82/146 (56%), Gaps = 12/146 (8%)
Query: 5 EKMTFPEKPSHKKYRAALKKEKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQLEEEKLL 64
E+ +K +K L +E K+RRQE + + EEE+ EE+QL E+
Sbjct: 957 ERQYRKDKKLQQKEEQLLGEEPEKRRRQEREK-------KYREEEELQQEEEQLLREERE 1009
Query: 65 ERERQRLHEEWLLREQKAQEEFRIKKEKEEAAKKRQEEQERKLKEQWEEQQRKER---EE 121
+R RQ ++ +++ QEE ++ +E+ E K+R +E+ER+ +E+ E QQ +E+ EE
Sbjct: 1010 KRRRQEWERQYRKKDELQQEEEQLLREERE--KRRLQERERQYREEEELQQEEEQLLGEE 1067
Query: 122 EEQKRQEKKEKEEALQKMLDQAENEL 147
E +R+++ E++ ++ L Q E +L
Sbjct: 1068 RETRRRQELERQYRKEEELQQEEEQL 1093
Score = 68.2 bits (165), Expect = 2e-11
Identities = 43/131 (32%), Positives = 82/131 (62%), Gaps = 8/131 (6%)
Query: 23 KKEKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQL---EEEKLLERERQRLHEEWLLRE 79
++E+R KR++E RL+ S+++ + +QL EEEK LE+ER+ E+ L RE
Sbjct: 514 RREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERR---EQRLKRE 570
Query: 80 QKAQEEFRIKKEKEEAAKKRQEEQERKLKEQW--EEQQRKEREEEEQKRQEKKEKEEALQ 137
Q+ + + +K+E+E ++ + EQE +L+++ EE +R E+EE ++R +++E EE +
Sbjct: 571 QEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERR 630
Query: 138 KMLDQAENELE 148
+ L ++E + E
Sbjct: 631 QQLLKSEEQEE 641
Score = 67.4 bits (163), Expect = 3e-11
Identities = 48/159 (30%), Positives = 87/159 (54%), Gaps = 25/159 (15%)
Query: 24 KEKRKKRRQELARL--RDSGLSQKEEEEDT--------FIEEQQL----EEEKLLERERQ 69
+E+++ RRQEL R + L Q+ E+E +EE+QL EE++L +ER
Sbjct: 1711 QEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERD 1770
Query: 70 R-LHEEWLLREQKAQEEFRIK------KEKEEAAKKRQEEQ----ERKLKEQWEEQQRKE 118
R EE LR+++ +++ R + +E+E+ ++R+E+Q +R K +WEE+Q +
Sbjct: 1771 RKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQL 1830
Query: 119 REEEEQKRQEKKEKEEALQKMLDQAENELENGTTWQNPE 157
E+E++ RQE+ + A ++ Q ++ E WQ E
Sbjct: 1831 EEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEE 1869
Score = 67.0 bits (162), Expect = 4e-11
Identities = 42/126 (33%), Positives = 78/126 (61%), Gaps = 7/126 (5%)
Query: 22 LKKEKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQLEEEKLLERERQRLH-EEWLLREQ 80
LK E+ ++R Q+ R+ L +++EE EQ+L+ ++ ER +QRL E+ L REQ
Sbjct: 489 LKLEEEERREQQ--ERREQQLRREQEER----REQRLKRQEEEERLQQRLRSEQQLRREQ 542
Query: 81 KAQEEFRIKKEKEEAAKKRQEEQERKLKEQWEEQQRKEREEEEQKRQEKKEKEEALQKML 140
+ + E +K+E+E+ ++ + EQ K +++ Q +REEE ++++ K+E+EE L++ L
Sbjct: 543 EERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRL 602
Query: 141 DQAENE 146
+ E E
Sbjct: 603 KREEVE 608
Score = 67.0 bits (162), Expect = 4e-11
Identities = 42/148 (28%), Positives = 89/148 (60%), Gaps = 10/148 (6%)
Query: 5 EKMTFPEKPSHKKYRAALKKEKRKKRRQELARLRDSGLSQKEEEEDTFI--EEQQLEEEK 62
E+ E+ +K+R L++E++++R A+ L ++ +E + EE++L+ E+
Sbjct: 861 ERRRSQEQRRDQKWRWQLEEERKRRRHTLYAK---PALQEQLRKEQQLLQEEEEELQREE 917
Query: 63 LLERERQRLHEEWLLREQKAQEEFRIKKEKEEAAKKRQEEQERKLKEQWEEQQRKER--- 119
+R RQ ++ EQ QEE ++ +E+ E K+R++E+ER+ ++ + QQ++E+
Sbjct: 918 REKRRRQEQERQYREEEQLQQEEEQLLREERE--KRRRQERERQYRKDKKLQQKEEQLLG 975
Query: 120 EEEEQKRQEKKEKEEALQKMLDQAENEL 147
EE E++R++++EK+ ++ L Q E +L
Sbjct: 976 EEPEKRRRQEREKKYREEEELQQEEEQL 1003
Score = 67.0 bits (162), Expect = 4e-11
Identities = 44/145 (30%), Positives = 83/145 (57%), Gaps = 10/145 (6%)
Query: 5 EKMTFPEKPSHKKYRAALKKEKRKKRRQELARL--RDSGLSQKEEEEDTFIEEQQLEEEK 62
E+ E+ ++ L++E+ K+RRQE R +D L QKEE+ + ++ E+ +
Sbjct: 927 ERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQ----LLGEEPEKRR 982
Query: 63 LLERERQRLHEEWLLREQKAQEEFRIKKEKEEAAKKRQEEQERKLKEQWEEQQRKEREEE 122
ERE++ EE L +E EE +++E+E+ ++ E Q RK E +E+++ REE
Sbjct: 983 RQEREKKYREEEELQQE----EEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREER 1038
Query: 123 EQKRQEKKEKEEALQKMLDQAENEL 147
E++R +++E++ ++ L Q E +L
Sbjct: 1039 EKRRLQERERQYREEEELQQEEEQL 1063
Score = 66.2 bits (160), Expect = 6e-11
Identities = 52/160 (32%), Positives = 89/160 (55%), Gaps = 18/160 (11%)
Query: 23 KKEKRKKRRQELAR-LRDSGLSQKEEEEDTFIEEQQLEEEKLLERERQRLHEEWLLREQK 81
++E++ RRQE R R+ L +E+ EEQ+L + ERER+ L EE LR Q+
Sbjct: 1347 EREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQ---ERERKFLKEEQQLRCQE 1403
Query: 82 AQEEFRI---KKEKEEAAKKRQEEQERKLKEQWEEQQRKERE-----EEEQKRQEK---- 129
+++ R +K +EE + ++E++RK +E+ ++ +R+ERE EE+Q RQE+
Sbjct: 1404 REQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKF 1463
Query: 130 KEKEEALQKMLDQAENELENGTTWQNPEPPVDFRVMEKDR 169
+E+E+ LQ+ +Q + E + E R E+DR
Sbjct: 1464 REEEQLLQEREEQQLHRQERDRKFLEEEQ--QLRRQERDR 1501
Score = 65.9 bits (159), Expect = 8e-11
Identities = 42/133 (31%), Positives = 76/133 (57%), Gaps = 13/133 (9%)
Query: 23 KKEKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQLEEEKLLERERQRLHEEWLL----- 77
+K ++++R Q L R ++ + EE+T EQ+ +++L + + E WL
Sbjct: 436 QKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEE 495
Query: 78 -REQKAQEEFRIKKEKEEAAK---KRQEEQERKLKEQWEEQQRKEREEEEQKRQEKKEKE 133
REQ+ + E ++++E+EE + KRQEE+ER L+++ +Q+ RE+EE++ Q K +E
Sbjct: 496 RREQQERREQQLRREQEERREQRLKRQEEEER-LQQRLRSEQQLRREQEERREQLLKREE 554
Query: 134 EALQKMLDQAENE 146
E K L+Q E
Sbjct: 555 E---KRLEQERRE 564
Score = 65.5 bits (158), Expect = 1e-10
Identities = 37/131 (28%), Positives = 80/131 (61%), Gaps = 11/131 (8%)
Query: 11 EKPSHKKYRAALKKEKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQL---EEEKLLERE 67
E+P ++ +++ RK RQEL R R ++E+++ EQQL +EE+ E++
Sbjct: 263 EEPQRQRELQEEEEQLRKLERQELRRERQ----EEEQQQQRLRREQQLRRKQEEERREQQ 318
Query: 68 RQRLHEEWLLREQKAQEEFRIKKEKEEAAKKRQEEQERKLKEQWEEQQRKEREEEEQKRQ 127
+R ++ +Q+ + E ++++E+EE R+E+Q R+ +E+ +Q+ RE+EE++R+
Sbjct: 319 EERREQQERREQQEERREQQLRREQEE----RREQQLRREQEEERREQQLRREQEEERRE 374
Query: 128 EKKEKEEALQK 138
++ +E+ L++
Sbjct: 375 QQLRREQQLRR 385
Score = 65.5 bits (158), Expect = 1e-10
Identities = 47/140 (33%), Positives = 80/140 (57%), Gaps = 21/140 (15%)
Query: 23 KKEKRKKRRQELAR----LRDSGLSQKEEEEDTFIEEQQLEEEKLLERERQRLHEEWLLR 78
++E++++R Q+L R R+ L ++EEEE +Q+L E+ L RE++ E+ L R
Sbjct: 496 RREQQERREQQLRREQEERREQRLKRQEEEERL---QQRLRSEQQLRREQEERREQLLKR 552
Query: 79 EQKAQEEFRIKKEKEEAAKKRQEEQERK---LKEQWEEQQRKEREEEEQKRQ-------E 128
E EE R+++E+ E KR++E+ R +E+ QQR +RE+EE+ Q E
Sbjct: 553 E----EEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVE 608
Query: 129 KKEKEEALQKMLDQAENELE 148
+ E+EE ++ L + E E E
Sbjct: 609 RLEQEERREQRLKREEPEEE 628
Score = 65.1 bits (157), Expect = 1e-10
Identities = 42/159 (26%), Positives = 87/159 (54%), Gaps = 9/159 (5%)
Query: 11 EKPSHKKYRAALKKEKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQLEEEKLLERERQR 70
E+ ++ R ++ + ++ R+E R+ L +++EEE EQQL E+ ER Q+
Sbjct: 320 ERREQQERREQQEERREQQLRREQEERREQQLRREQEEER---REQQLRREQEEERREQQ 376
Query: 71 LH-EEWLLREQKAQEEFRIKKEKEEAAKKR-QEEQERKLKEQWEEQQRKEREEEEQKRQE 128
L E+ L REQ+ + E ++++E++ +++ + EQ+ + ++Q +Q+ RE+EE++ ++
Sbjct: 377 LRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQ 436
Query: 129 KKEKEEALQKMLDQAENELENGTTWQNPEPPVDFRVMEK 167
K E+E Q++ + E E W E + E+
Sbjct: 437 KHEQERREQRL----KREQEERRDWLKREEETERHEQER 471
Score = 64.7 bits (156), Expect = 2e-10
Identities = 61/236 (25%), Positives = 107/236 (45%), Gaps = 28/236 (11%)
Query: 11 EKPSHKKYRAALKKEKRKKRRQELARL-----RDSGLSQKEEEEDTFIEEQQLEEEKLLE 65
E+P ++ + LK E++++RRQ+ R R+ L ++EEEE EQ+L+ E E
Sbjct: 623 EEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERL---EQRLKREHEEE 679
Query: 66 RERQRLHEEWLLREQKAQEEFRIKKEK-----EEAAKKRQEEQERKLKEQWEEQQRKERE 120
R Q L EE +++A+E + + K E A RQ + + ++Q +++R+E+E
Sbjct: 680 RREQELAEE---EQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQE 736
Query: 121 EEEQKRQEKKEKEEALQKMLDQAENELENGTTWQNPEPPVDFRVMEKDRANCPF-YSKTG 179
E+ ++R+ + + +E + Q E E TWQ R ++ A P +
Sbjct: 737 EKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRER 796
Query: 180 ACRFGDRCSRKHNFPTSSPTLLIKSMFTTFGMEQCRRDDYDPDASLEYSEEETYQQ 235
R +R R+ F EQ RR + + L++ EEE Q
Sbjct: 797 QLRAEERQQREQRFLPEEEE-----------KEQRRRQRREREKELQFLEEEEQLQ 841
Score = 64.3 bits (155), Expect = 2e-10
Identities = 54/174 (31%), Positives = 91/174 (52%), Gaps = 25/174 (14%)
Query: 5 EKMTFPEKPSHKKYRAALKKEKRKKRRQELARLRDSGLSQKEEEEDTFI---EEQQL--- 58
E+ + +K+ + +R++R Q+L RD +K EE+ + EEQQL
Sbjct: 1632 EEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRD----RKFREEEQLLQEGEEQQLRRQ 1687
Query: 59 -------EEEKLL---ERERQRLHEEWLLREQKAQEEFRIKKE-KEEAAKKRQEEQERKL 107
EEE+ L ERER+ L EE LR Q+ + +FR +++ ++E +++ QER
Sbjct: 1688 ERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYR 1747
Query: 108 KEQWEEQQRKEREEEEQKRQEK----KEKEEALQKMLDQAENELENGTTWQNPE 157
K EEQ R EREE++ +RQE+ +E+E+ Q+ +Q E+ ++ E
Sbjct: 1748 KILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEE 1801
Score = 63.9 bits (154), Expect = 3e-10
Identities = 52/171 (30%), Positives = 84/171 (49%), Gaps = 36/171 (21%)
Query: 19 RAALKKEKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQLEEEKLLERERQRLHEEWLLR 78
R L++E++ +R++ + R+ L +E E EEQQL + +R+R+ L EE LR
Sbjct: 1485 RKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQ---QRQRKFLQEEQQLR 1541
Query: 79 EQ------------KAQEEFRIKKEKEEAAKKRQE---------------EQERKLKEQW 111
Q K +EE ++++E+EE RQE EQERK E
Sbjct: 1542 RQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFME-- 1599
Query: 112 EEQQRKEREEEEQKRQEK----KEKEEALQKMLDQAENELENGTTWQNPEP 158
+EQQ + +E ++Q RQE+ +E E+ LQ+ +Q + E + EP
Sbjct: 1600 DEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEP 1650
Score = 63.9 bits (154), Expect = 3e-10
Identities = 46/139 (33%), Positives = 79/139 (56%), Gaps = 17/139 (12%)
Query: 23 KKEKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQLEEEKLLERERQRLHEEWLL----- 77
++E+ +K QE +LR L +K EE+ +E + E+ + ER R+ L EE L
Sbjct: 1702 RQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREE 1761
Query: 78 -------REQKAQEEFRIKKEKEEAAKKRQEEQERKLKEQWEEQQRKEREEEEQKRQEK- 129
R++K +EE ++++E+EE + R +E +RK +E EEQ R+EREE++ + Q++
Sbjct: 1762 QQLRRQERDRKFREEEQLRQEREEQ-QLRSQESDRKFRE--EEQLRQEREEQQLRPQQRD 1818
Query: 130 -KEKEEALQKMLDQAENEL 147
K + E Q L++ E L
Sbjct: 1819 GKYRWEEEQLQLEEQEQRL 1837
Score = 63.5 bits (153), Expect = 4e-10
Identities = 46/154 (29%), Positives = 89/154 (57%), Gaps = 20/154 (12%)
Query: 11 EKPSHKKYRAALKKEKRKKRRQELARLRDSGLSQKEEEEDTFIEEQ--------QLEEEK 62
++ +K L++E++ +RR+ +L++ +E++E +EQ QLEEE+
Sbjct: 823 QRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEER 882
Query: 63 LLERERQRLHEEWLLREQKAQEEFRIKKEKEEAAK------KRQEEQERKLKEQWEEQQR 116
+R R L+ + L+EQ +E+ +++E+EE + +RQ EQER+ +E+ + QQ
Sbjct: 883 --KRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQ-EQERQYREEEQLQQE 939
Query: 117 KE---REEEEQKRQEKKEKEEALQKMLDQAENEL 147
+E REE E++R++++E++ K L Q E +L
Sbjct: 940 EEQLLREEREKRRRQERERQYRKDKKLQQKEEQL 973
Score = 62.4 bits (150), Expect = 9e-10
Identities = 42/132 (31%), Positives = 74/132 (56%), Gaps = 8/132 (6%)
Query: 23 KKEKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQLE--EEKLLERERQRLHEE----WL 76
++E+R KR QE RD L ++EE ++ +Q E E++L E +RL +E
Sbjct: 562 RREQRLKREQE--ERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQR 619
Query: 77 LREQKAQEEFRIKKEKEEAAKKRQEEQERKLKEQWEEQQRKEREEEEQKRQEKKEKEEAL 136
L+ ++ +EE R + K E ++R+++Q R+ +++ EQ+ K EEEE+ Q K + E
Sbjct: 620 LKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEE 679
Query: 137 QKMLDQAENELE 148
++ + AE E E
Sbjct: 680 RREQELAEEEQE 691
Score = 62.0 bits (149), Expect = 1e-09
Identities = 36/123 (29%), Positives = 68/123 (55%)
Query: 12 KPSHKKYRAALKKEKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQLEEEKLLERERQRL 71
K ++ R L K + ++R+Q L R ++ L Q+ + E+ EQ+ E+ L+RE
Sbjct: 568 KREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEE 627
Query: 72 HEEWLLREQKAQEEFRIKKEKEEAAKKRQEEQERKLKEQWEEQQRKEREEEEQKRQEKKE 131
L + + QEE R ++ + E ++R++ +R+ +E+ EQ+ K EEE++ QE E
Sbjct: 628 ERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAE 687
Query: 132 KEE 134
+E+
Sbjct: 688 EEQ 690
Score = 61.2 bits (147), Expect = 2e-09
Identities = 44/158 (27%), Positives = 87/158 (55%), Gaps = 33/158 (20%)
Query: 23 KKEKRKK----------------------RRQELARLRDSGLSQK-----EEEEDTFIEE 55
++E+R+ RR+EL LR G +K E ++ F EE
Sbjct: 182 EREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEE 241
Query: 56 QQLE---EEKLLERERQRLHEEWLLREQKAQEEFR--IKKEKEEAAKKRQEEQERKLKEQ 110
++ E E +L +E ++L EE R+++ QEE K E++E ++RQEE++++ + +
Sbjct: 242 EEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLR 301
Query: 111 WEEQQRKEREEEEQKRQ-EKKEKEEALQKMLDQAENEL 147
E+Q R+++EEE +++Q E++E++E ++ ++ E +L
Sbjct: 302 REQQLRRKQEEERREQQEERREQQERREQQEERREQQL 339
Score = 61.2 bits (147), Expect = 2e-09
Identities = 35/130 (26%), Positives = 84/130 (64%), Gaps = 5/130 (3%)
Query: 11 EKPSHKKYRAALKKEKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQLEEEKLLERERQR 70
E+ ++ + L++E++ +R+QE R R+ ++E++E E+Q+ E+ L RE++
Sbjct: 289 ERQEEEQQQQRLRREQQLRRKQEEER-REQQEERREQQERR--EQQEERREQQLRREQEE 345
Query: 71 LHEEWLLREQKAQE-EFRIKKEKEEAAKKRQEEQERKL-KEQWEEQQRKEREEEEQKRQE 128
E+ L REQ+ + E ++++E+EE +++Q +E++L +EQ ++++ R E++ +R++
Sbjct: 346 RREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQ 405
Query: 129 KKEKEEALQK 138
+ +E+ L++
Sbjct: 406 QLRREQQLRR 415
Score = 60.5 bits (145), Expect = 3e-09
Identities = 41/146 (28%), Positives = 86/146 (58%), Gaps = 9/146 (6%)
Query: 5 EKMTFPEKPSHKKYRAALKKEKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQLEEEKLL 64
E+ + +K+ ++ +R++ +Q+L + RD +K E++ ++E++ ++
Sbjct: 1584 EEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERD----RKFREDEQLLQEREEQQLHRQ 1639
Query: 65 ERERQRLHEEWLLREQKAQEEFRIKKEKE--EAAKKRQEEQERKLKEQWEEQQRKEREEE 122
ER+R+ L EE LR Q+ +++ R ++++ E + QE +E++L+ Q E+ RK REEE
Sbjct: 1640 ERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQ--ERDRKFREEE 1697
Query: 123 EQKRQEKKEKEEALQKMLDQAENELE 148
+Q R++++E+ + LQ+ ELE
Sbjct: 1698 QQLRRQERER-KFLQEEQQLRRQELE 1722
Score = 60.1 bits (144), Expect = 4e-09
Identities = 42/132 (31%), Positives = 73/132 (55%), Gaps = 15/132 (11%)
Query: 10 PEKPSHKKYRAALKKEKRKKRRQELARLRDSGLSQKEEEEDT---FIEEQQLEEEKLLER 66
P K ++ R ++EKR++R EL + ++++EE+ F + Q EE+ ER
Sbjct: 723 PRKQEGQRRRQE-QEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKS--ER 779
Query: 67 ERQRLHEEWLLREQKAQEEFRIKKEKEEAAKKRQEEQERKLKEQWEEQQRKEREEEEQKR 126
RQRL LREQ +E++ A++RQ+ ++R L E+ E++QR+ + E +K
Sbjct: 780 GRQRLSARPPLREQ---------RERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKE 830
Query: 127 QEKKEKEEALQK 138
+ E+EE LQ+
Sbjct: 831 LQFLEEEEQLQR 842
Score = 59.7 bits (143), Expect = 6e-09
Identities = 43/147 (29%), Positives = 82/147 (55%), Gaps = 23/147 (15%)
Query: 12 KPSHKKYRAALKKEKRKK-----RRQELARL-----RDSGLSQKEEEEDTFIEEQQLEEE 61
K ++ + LK+E+ ++ +R+E+ RL R+ L ++E EE+ +Q L+ E
Sbjct: 580 KREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEER--RQQLLKSE 637
Query: 62 KLLERERQRLHEEWLLREQKAQEEFRIKKEKEEAAKKRQEEQERKLKEQWEEQQRKEREE 121
+ ER +Q+L REQ+ + E R+K+E+EE E E++LK + EE++R++
Sbjct: 638 EQEERRQQQLR-----REQQERREQRLKREEEE------ERLEQRLKREHEEERREQELA 686
Query: 122 EEQKRQEKKEKEEALQKMLDQAENELE 148
EE++ Q ++ + + K Q E+E +
Sbjct: 687 EEEQEQARERIKSRIPKWQWQLESEAD 713
Score = 59.7 bits (143), Expect = 6e-09
Identities = 46/154 (29%), Positives = 86/154 (55%), Gaps = 17/154 (11%)
Query: 10 PEKPSHKKYRAALKKEKRKKRRQELARLR--DSGLSQKEEEEDTFIEEQQL----EEEKL 63
PE+ ++ + ++++++K QE +LR + G ++++ + F EE+QL EE++L
Sbjct: 1513 PERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQL 1572
Query: 64 LERERQRLHEEWLLREQKAQEEFRIKKEKEEAAKKRQEE------QERKLKEQWEEQQRK 117
+ER R ++ L EQK + + + +K E+ + R++E QER K + +EQ +
Sbjct: 1573 SRQERDR---KFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQ 1629
Query: 118 EREEEEQKRQEKKEK--EEALQKMLDQAENELEN 149
EREE++ RQE+ K EE Q + E +L +
Sbjct: 1630 EREEQQLHRQERDRKFLEEEPQLRRQEREQQLRH 1663
Score = 58.9 bits (141), Expect = 1e-08
Identities = 42/142 (29%), Positives = 85/142 (59%), Gaps = 19/142 (13%)
Query: 22 LKKEKRKKRRQE--LARLRDSGLSQKEEEEDTFIEE------QQLEEEKLLERERQRLHE 73
L++E+ +K R++ L + R+ ++E + F+EE Q+ E++ +R+R+ E
Sbjct: 1613 LRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREE 1672
Query: 74 EWLLR---EQKAQEEFRIKKEKEEAAKKRQEEQERKLKEQWEEQQRKERE----EEEQKR 126
E LL+ EQ+ + + R +K +EE + R++E+ERK ++ ++ +R+E E EEEQ R
Sbjct: 1673 EQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLR 1732
Query: 127 QEKKE----KEEALQKMLDQAE 144
QE ++ ++E +K+L++ +
Sbjct: 1733 QETEQEQLRRQERYRKILEEEQ 1754
Score = 58.5 bits (140), Expect = 1e-08
Identities = 39/125 (31%), Positives = 76/125 (60%), Gaps = 13/125 (10%)
Query: 22 LKKEKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQ-----LEEEKLLERERQR--LHEE 74
L++++ +K R+E +L +K EE+ + Q+ LEEE+ L +ER R EE
Sbjct: 1408 LRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEE 1467
Query: 75 WLLREQKAQEEFRIKKEK---EEAAKKRQEEQERKLKEQ---WEEQQRKEREEEEQKRQE 128
LL+E++ Q+ R ++++ EE + R++E++RK +EQ +E +RK EEE+Q ++
Sbjct: 1468 QLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQ 1527
Query: 129 KKEKE 133
+++++
Sbjct: 1528 QRQRK 1532
Score = 57.8 bits (138), Expect = 2e-08
Identities = 46/142 (32%), Positives = 82/142 (57%), Gaps = 19/142 (13%)
Query: 16 KKYRAALKKEKR---KKRRQELARLRD-------SGLSQKEEEEDTFIEEQQLEEEKLLE 65
++ R LK+E++ ++R Q+L + RD LS++E + EEQQ+ + E
Sbjct: 1387 ERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQ---E 1443
Query: 66 RERQRLHEEWLLREQ---KAQEEFRIKKEKEEAAKKRQEEQERKLKEQWEEQQRKEREEE 122
RER+ L EE LR++ K +EE ++ +E+EE RQ E++RK E EEQQ + +E +
Sbjct: 1444 RERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQ-ERDRKFLE--EEQQLRRQERD 1500
Query: 123 EQKRQEKKEKEEALQKMLDQAE 144
+ R+++ +E +K L++ +
Sbjct: 1501 RKFREQELRSQEPERKFLEEEQ 1522
Score = 57.4 bits (137), Expect = 3e-08
Identities = 48/165 (29%), Positives = 89/165 (53%), Gaps = 20/165 (12%)
Query: 23 KKEKRKKRRQELAR-LRDSGLSQKEEEEDTFIEEQQL----EEEKL--LERERQRLHEEW 75
++E+++ RRQE R + ++E F EE+QL EE++L ER+R+ L EE
Sbjct: 1433 REEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQ 1492
Query: 76 LLREQKAQEEFRIKKEKEEAAKKRQEEQERKLKEQ-------WEEQQRKEREEEEQKRQE 128
LR Q+ +FR ++ + + +++ E+E++L Q EEQQ + +E +Q+RQ+
Sbjct: 1493 QLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQD 1552
Query: 129 K----KEKEEALQKMLDQAENELENGTTWQNPEPPVDFRVMEKDR 169
+ +E+E+ Q+ +Q + E ++ E V R E++R
Sbjct: 1553 RDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKV--RRQEQER 1595
Score = 57.0 bits (136), Expect = 4e-08
Identities = 47/153 (30%), Positives = 80/153 (52%), Gaps = 35/153 (22%)
Query: 22 LKKEKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQLEEEKLLERERQRLHE-------E 74
L++E ++RRQ+ Q++E E EEQ ++E+L +R+RQR E E
Sbjct: 129 LEEEPGQRRRQK---------RQEQERELAEGEEQSEKQERLEQRDRQRRDEELWRQRQE 179
Query: 75 WLLREQKAQEEFRIKKEK---------EEAAKKRQEEQERKLKEQWEEQQRKER-----E 120
W RE++ EE +++ K EE ++R+ + R+ + ++QQR+ER +
Sbjct: 180 WQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQ 239
Query: 121 EEEQKRQEKKE-----KEEALQKMLDQAENELE 148
EEE+K K+E +EE LQ+ Q + EL+
Sbjct: 240 EEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQ 272
Score = 57.0 bits (136), Expect = 4e-08
Identities = 41/140 (29%), Positives = 80/140 (57%), Gaps = 16/140 (11%)
Query: 11 EKPSHKKYRAALKKEKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQLEEEKLLERERQR 70
++ + +R + ++R++RR E +L+ S K E + F +E+QL +LLE R+
Sbjct: 167 QRRDEELWRQRQEWQEREERRAEEEQLQ----SCKGHETEEFPDEEQLRRRELLELRRKG 222
Query: 71 LHEEWLLREQKAQEEFRIKKEKE----------EAAKKRQEEQERKLKEQWEEQQ-RK-E 118
E+ R ++ F+ ++EKE E K ++EE +R+ + Q EE+Q RK E
Sbjct: 223 REEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLE 282
Query: 119 REEEEQKRQEKKEKEEALQK 138
R+E ++RQE++++++ L++
Sbjct: 283 RQELRRERQEEEQQQQRLRR 302
Score = 56.6 bits (135), Expect = 5e-08
Identities = 50/180 (27%), Positives = 90/180 (50%), Gaps = 30/180 (16%)
Query: 11 EKPSHKKYRAALKKEKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQLEEEKLLE---RE 67
++ S + + L +++ + R QE R ++ + F EE+QLE E+ E R+
Sbjct: 1260 DRQSQQDLQHLLGEQQERDREQERRRW--------QQRDRHFPEEEQLEREEQKEAKRRD 1311
Query: 68 RQRLHEEWLLREQ------------KAQEEFRIKKEKEEAAKKRQEEQERKLKEQ---WE 112
R+ E+ LLRE+ K +EE ++ +E+EE +RQ E++RK +E+ +
Sbjct: 1312 RKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQ-ERDRKFREEELRHQ 1370
Query: 113 EQQRKEREEEEQKRQEKKEK---EEALQKMLDQAENELENGTTWQNPEPPVDFRVMEKDR 169
EQ RK EEE++ R++++E+ +E Q + E +L + E E+DR
Sbjct: 1371 EQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDR 1430
Score = 56.6 bits (135), Expect = 5e-08
Identities = 50/170 (29%), Positives = 84/170 (49%), Gaps = 27/170 (15%)
Query: 22 LKKEKRKKRRQE--LARLRDSGLSQKEEEEDTFIEEQQLEEEKLLERERQRLHEEWLLRE 79
L++E+ +K R+E L + R+ ++E + F+EE+Q +L +ER R E LR
Sbjct: 1455 LRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQ----QLRRQERDRKFREQELRS 1510
Query: 80 QKAQEEF-----------RIKKEKEEAAKKRQEE------QERKLKEQWEEQQRKEREEE 122
Q+ + +F R +K +E + R++E Q+R K + EEQ R+EREE+
Sbjct: 1511 QEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQ 1570
Query: 123 EQKRQEKKEK---EEALQKMLDQAENELENGTTWQNPEPPVDFRVMEKDR 169
+ RQE+ K EE + +Q +E+ + E R E+DR
Sbjct: 1571 QLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLR-QERDR 1619
Score = 56.2 bits (134), Expect = 6e-08
Identities = 41/141 (29%), Positives = 79/141 (56%), Gaps = 17/141 (12%)
Query: 23 KKEKRKKRRQELARL--RDSGLSQKEEEEDTFIEEQ----QLEEEKL--LERERQRLHEE 74
++E+ ++RRQ+ R + L Q+ EE+ +E+ +LEE+K+ E+ER+ + +E
Sbjct: 1542 RQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDE 1601
Query: 75 WLLREQKAQEEFRIK-----KEKEEAAKKRQEE----QERKLKEQWEEQQRKEREEEEQK 125
LR Q+ Q++ R + +E E+ ++R+E+ QER K EE Q + +E E+Q
Sbjct: 1602 QQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQL 1661
Query: 126 RQEKKEKEEALQKMLDQAENE 146
R ++ K +++L + E +
Sbjct: 1662 RHDRDRKFREEEQLLQEGEEQ 1682
Score = 55.8 bits (133), Expect = 8e-08
Identities = 41/136 (30%), Positives = 79/136 (58%), Gaps = 13/136 (9%)
Query: 11 EKPSHKKYRAALKKEKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQL------EEEKLL 64
E+ S K+ R L++ R++R +EL R R + +E E+ EE+QL E E+
Sbjct: 152 EEQSEKQER--LEQRDRQRRDEELWRQRQ----EWQEREERRAEEEQLQSCKGHETEEFP 205
Query: 65 ERERQRLHEEWLLREQKAQEEFRIKKEKEEAAKKRQEEQERKLKEQWEEQQRKEREEEEQ 124
+ E+ R E LR + +E+ + ++E+++ + +EE+E + +E ++ ++ +EEE
Sbjct: 206 DEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEP 265
Query: 125 KRQ-EKKEKEEALQKM 139
+RQ E +E+EE L+K+
Sbjct: 266 QRQRELQEEEEQLRKL 281
Score = 55.8 bits (133), Expect = 8e-08
Identities = 43/156 (27%), Positives = 84/156 (53%), Gaps = 21/156 (13%)
Query: 9 FPEKPS--HKKYRAALKKEKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQL----EEEK 62
FPE+ ++ + A +++++ + ++L R +++E + F EE+QL EE+
Sbjct: 1293 FPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQP 1352
Query: 63 LLERERQRLHEEWLLREQKA-----QEEFRIKKEKEEAAKKRQEEQ------ERKLKEQW 111
L +ER R E LR Q+ +EE R+++++ E ++E+Q E++L+
Sbjct: 1353 LRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLR--- 1409
Query: 112 EEQQRKEREEEEQ-KRQEKKEKEEALQKMLDQAENE 146
+++ RK REEE+Q RQE+ K ++ + + E E
Sbjct: 1410 QDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERE 1445
Score = 55.8 bits (133), Expect = 8e-08
Identities = 59/244 (24%), Positives = 118/244 (48%), Gaps = 30/244 (12%)
Query: 11 EKPSHKKYRAALKKEKRKKRRQELARLR----DSGLSQKEEEEDTFIEEQQLEEEKLLER 66
E+ ++ R +++ R ++ +E +LR + LS++E + +EEQ++ + E+
Sbjct: 1537 EQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQ---EQ 1593
Query: 67 ERQRLHEEWLLREQKAQEEFRIKKEKE--EAAKKRQEEQERKLKEQWEEQQRKEREEEEQ 124
ER+ + +E LR Q+ Q++ R +++++ E + QE +E++L Q E+ RK EEE Q
Sbjct: 1594 ERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQ--ERDRKFLEEEPQ 1651
Query: 125 KRQEKKEKE--EALQKMLDQAENELENGTTWQNPEPPVDFRVMEKDRANCPFYSKTGACR 182
R++++E++ + + E L+ G Q R E+DR F + R
Sbjct: 1652 LRRQEREQQLRHDRDRKFREEEQLLQEGEEQQ-------LRRQERDR---KFREEEQQLR 1701
Query: 183 FGDRCSRKHNFPTSSPTLLIKSMFTTFGMEQCRRDDYDPDASLEYSEEETYQQFLDFYED 242
R R+ F L + + F E+ R + + + + +E Y++ L+ E
Sbjct: 1702 ---RQERERKFLQEEQQLRRQELERKFREEEQLRQETEQE---QLRRQERYRKILE-EEQ 1754
Query: 243 VLPE 246
+ PE
Sbjct: 1755 LRPE 1758
Score = 55.8 bits (133), Expect = 8e-08
Identities = 45/173 (26%), Positives = 91/173 (52%), Gaps = 24/173 (13%)
Query: 5 EKMTFPEKPSHKKYRAALKKEKRKKRRQELARLRDSGLSQKEEEE-DTFIEEQQL----- 58
E+ + +K+R +++ R++R ++ R ++S +EEE+ EEQQL
Sbjct: 1760 EEQQLRRQERDRKFRE--EEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQR 1817
Query: 59 ------EEEKL-LERERQRLHEEWLLREQKAQEEFRIKKEK--------EEAAKKRQEEQ 103
EEE+L LE + QRL +E R+ +A+E+F +++ +E +KR++E+
Sbjct: 1818 DGKYRWEEEQLQLEEQEQRLRQE-RDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQER 1876
Query: 104 ERKLKEQWEEQQRKEREEEEQKRQEKKEKEEALQKMLDQAENELENGTTWQNP 156
ERKL+E+ +Q+KE + Q + K ++ + ++L+ ++ + +P
Sbjct: 1877 ERKLREEHIRRQQKEEQRHRQVGEIKSQEGKGHGRLLEPGTHQFASVPVRSSP 1929
Score = 55.1 bits (131), Expect = 1e-07
Identities = 38/149 (25%), Positives = 76/149 (51%), Gaps = 12/149 (8%)
Query: 25 EKRKKRRQELARLRDSGLSQKE----EEEDTFIEEQQLEEEKLLERERQRLHEEWLLREQ 80
++ + RR+EL LR G +K+ E +D +E+ EE++ +RE EE L+E+
Sbjct: 206 DEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEE--EEKEWRKRETVLRKEEEKLQEE 263
Query: 81 KAQEEFRIKKEKEEAAKKRQEEQERKLKEQWEEQQRKEREEEEQKRQEKKEKEEALQKML 140
+ Q + +++E+E+ K ++E R+ +E+ ++QQR RE Q+ + K+E ++
Sbjct: 264 EPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRRE------QQLRRKQEEERREQ 317
Query: 141 DQAENELENGTTWQNPEPPVDFRVMEKDR 169
+ E + Q R +++R
Sbjct: 318 QEERREQQERREQQEERREQQLRREQEER 346
Score = 55.1 bits (131), Expect = 1e-07
Identities = 45/133 (33%), Positives = 76/133 (57%), Gaps = 11/133 (8%)
Query: 23 KKEKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQL-EEEKLLERERQRLHEEWLLREQK 81
++EK ++RRQ R ++ ++EE+ QQL EEE L+ +++R + R+QK
Sbjct: 814 EEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQK 873
Query: 82 AQ---EEFRIKKEKEEAAKKRQEEQERK----LKEQWEEQQRKEREEEEQKRQEKKEKEE 134
+ EE R ++ AK +EQ RK L+E+ EE QR+ERE+ ++RQE +E++
Sbjct: 874 WRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREK--RRRQE-QERQY 930
Query: 135 ALQKMLDQAENEL 147
++ L Q E +L
Sbjct: 931 REEEQLQQEEEQL 943
Score = 54.3 bits (129), Expect = 2e-07
Identities = 33/129 (25%), Positives = 74/129 (57%), Gaps = 7/129 (5%)
Query: 23 KKEKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQLE--EEKLLERERQRLHEEWLLREQ 80
K+E+ ++ +QE R + Q+EE + + +Q E E++L + + E+ L REQ
Sbjct: 309 KQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQ 368
Query: 81 KAQEEFRIKKEKEEAAKKRQEEQERKLKEQWEEQQRKE---REEEEQKRQEKKEKEEALQ 137
+EE R ++ + E +R+++ R+ + + E+Q R+E R E++ +R+++ +E+ L+
Sbjct: 369 --EEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLR 426
Query: 138 KMLDQAENE 146
+ ++ +E
Sbjct: 427 REQEEERHE 435
Score = 53.9 bits (128), Expect = 3e-07
Identities = 39/153 (25%), Positives = 84/153 (54%), Gaps = 19/153 (12%)
Query: 29 KRRQELARLRDSGLSQKEEEEDTFIEEQQLEEEKLLERERQRLHEEWLLREQKAQEEFRI 88
+ ++ +L DS L ++ ++D + L E++ +RE++R W R++ EE ++
Sbjct: 1245 RENEQFRQLEDSQLRDRQSQQDL---QHLLGEQQERDREQER--RRWQQRDRHFPEEEQL 1299
Query: 89 KKEKEEAAKKR---QEEQERKLKEQWEEQQRKER-----EEEEQKRQEKKE----KEEAL 136
++E+++ AK+R +E+++ L+E+ EE++R++ EEEQ QE++E ++E
Sbjct: 1300 EREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERD 1359
Query: 137 QKMLDQAENELENGTTWQNPEPPVDFRVMEKDR 169
+K ++ E G + E + R E++R
Sbjct: 1360 RKFREEELRHQEQGRKFLEEEQRL--RRQERER 1390
Score = 53.1 bits (126), Expect = 5e-07
Identities = 35/149 (23%), Positives = 78/149 (52%), Gaps = 20/149 (13%)
Query: 11 EKPSHKKYRAALKKEKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQLEEEKLLERERQR 70
EK + R + + R++R ++L ++++ E F+ E++ +E++ +R +
Sbjct: 775 EKSERGRQRLSARPPLREQRERQLRA------EERQQREQRFLPEEEEKEQRRRQRRERE 828
Query: 71 LHEEWLLREQKAQEEFRIKKEKEEAAKKRQEEQERKLKEQWEEQQRKEREEEEQKR---- 126
++L E++ Q R ++ +EE +++++ R+ +EQ +Q+ + + EEE+KR
Sbjct: 829 KELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHT 888
Query: 127 -------QEKKEKEEALQKMLDQAENELE 148
QE+ KE Q++L + E EL+
Sbjct: 889 LYAKPALQEQLRKE---QQLLQEEEEELQ 914
Score = 51.6 bits (122), Expect = 2e-06
Identities = 55/200 (27%), Positives = 88/200 (44%), Gaps = 68/200 (34%)
Query: 5 EKMTFPEKPSHKKYRAALKKEKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQL----EE 60
E+ E+ ++ L++E K+RRQEL R Q EEE+ EE+QL +E
Sbjct: 1137 ERQYREEEEVQQEEEQLLREEPEKRRRQELER-------QYREEEELQQEEEQLLREEQE 1189
Query: 61 EKLLERERQRLHEEWLLREQKAQE----------EFRIKKEKEEAA-------KKRQEEQ 103
++ ERERQ EE L R+++ Q +++ + EKE A K R+ EQ
Sbjct: 1190 KRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQ 1249
Query: 104 ERKLKE-----------------------------QW--------EEQQRKEREEEEQKR 126
R+L++ +W EE+Q + E++E KR
Sbjct: 1250 FRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKR 1309
Query: 127 QEKKEKEEALQKMLDQAENE 146
+++K +EE K L + E E
Sbjct: 1310 RDRKSQEE---KQLLREERE 1326
Score = 49.3 bits (116), Expect = 8e-06
Identities = 42/150 (28%), Positives = 79/150 (52%), Gaps = 21/150 (14%)
Query: 11 EKPSHKKYRAALKKEKRKKRRQELAR--LRDSGLSQKEEEEDTFIEEQQL----EEEKLL 64
E+ H++ +E+++ RRQE R L++ + +E E +++ EE++L
Sbjct: 1365 EELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLS 1424
Query: 65 ERERQRLHEEWLLREQKAQEEFRIKKEKEEAAKKRQE------EQERKLKEQWEEQ---- 114
+ER R E EQ+ + + R +K EE + RQE E+E+ L+E+ E+Q
Sbjct: 1425 RQERDRKFRE---EEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQ 1481
Query: 115 --QRKEREEEEQKRQEKKEKEEALQKMLDQ 142
RK EEE+Q R+++++++ Q++ Q
Sbjct: 1482 ERDRKFLEEEQQLRRQERDRKFREQELRSQ 1511
Score = 48.1 bits (113), Expect = 2e-05
Identities = 33/114 (28%), Positives = 66/114 (57%), Gaps = 6/114 (5%)
Query: 22 LKKEKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQLEEEKLLERERQRLHEEWLLREQK 81
L +EKR + + + L+D Q+E++ ++QLEEE R ++R +E L E +
Sbjct: 95 LDEEKRARCDGKESLLQDR--RQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGE 152
Query: 82 AQEEFRIKKEK-EEAAKKRQEEQERKLKEQWEEQQRKEREEEEQKRQEKKEKEE 134
Q E K+E+ E+ ++R++E+ + +++W+E++ + EEE+ + + E EE
Sbjct: 153 EQSE---KQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEE 203
Score = 45.8 bits (107), Expect = 9e-05
Identities = 30/91 (32%), Positives = 53/91 (58%), Gaps = 3/91 (3%)
Query: 48 EEDTFIEEQQLEEEKLLE-RERQRLHEEWLLREQKAQEEFRIKKEKEEAAKKRQEEQERK 106
+E + +Q E+++ E R+RQ E R QK QE+ R E EE ++K++ ++R
Sbjct: 106 KESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRD 165
Query: 107 LKEQWEEQQRKEREEEEQKRQEKKEKEEALQ 137
+ + EE R + +E Q+R+E++ +EE LQ
Sbjct: 166 RQRRDEELWR--QRQEWQEREERRAEEEQLQ 194
Score = 43.9 bits (102), Expect = 3e-04
Identities = 36/164 (21%), Positives = 74/164 (45%), Gaps = 25/164 (15%)
Query: 4 PEKMTFPEKPSHKKYRAALKKEKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQLEEEKL 63
PEK E + L++E+ + R+E + R Q EEE+ ++ Q+ ++
Sbjct: 1158 PEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEE--LQRQKRKQRYR 1215
Query: 64 LERERQRLHEEWLLREQKA------------QEEFRIKKEKEEAAKKRQEEQERKLKEQ- 110
E +R L +W ++ A E+FR ++ + ++ Q++ + L EQ
Sbjct: 1216 DEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQ 1275
Query: 111 ----------WEEQQRKEREEEEQKRQEKKEKEEALQKMLDQAE 144
W+++ R EEE+ +R+E+KE + +K ++ +
Sbjct: 1276 ERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQ 1319
Score = 38.5 bits (88), Expect = 0.014
Identities = 23/93 (24%), Positives = 53/93 (56%), Gaps = 9/93 (9%)
Query: 65 ERERQRLH-EEWLLREQKAQEEFR--------IKKEKEEAAKKRQEEQERKLKEQWEEQQ 115
E +R R +E LL++++ +E+ R +++E + +++++EQER+L E E+ +
Sbjct: 97 EEKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSE 156
Query: 116 RKEREEEEQKRQEKKEKEEALQKMLDQAENELE 148
++ER E+ +++ +E Q+ ++ E E
Sbjct: 157 KQERLEQRDRQRRDEELWRQRQEWQEREERRAE 189
Score = 36.2 bits (82), Expect = 0.068
Identities = 15/71 (21%), Positives = 44/71 (61%), Gaps = 1/71 (1%)
Query: 84 EEFRIKKEKEEAAKKRQEEQERKLKEQWEEQQRKEREEEEQKRQEKKEKEEALQKMLDQA 143
+E ++ ++E ++R E ++R+L+E+ Q+R+++ +E+++ + E++ Q+ L+Q
Sbjct: 106 KESLLQDRRQEEDQRRFEPRDRQLEEE-PGQRRRQKRQEQERELAEGEEQSEKQERLEQR 164
Query: 144 ENELENGTTWQ 154
+ + + W+
Sbjct: 165 DRQRRDEELWR 175
Score = 34.3 bits (77), Expect = 0.26
Identities = 21/105 (20%), Positives = 39/105 (37%)
Query: 363 RRERMGHHDDYYSRLRGRRNPSPDHSYKRNGESERKSSRHRGKKSHKRTSKSRERHNSRS 422
RRER R ++ +R + ER+ + R ++ +R + R
Sbjct: 287 RRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEER 346
Query: 423 RGRNRDRSRDRSRGRGSRSRSRSRSRRSRRSRSQSSSRSRSRGRR 467
R + R ++ R R + RR ++ R + R + RR
Sbjct: 347 REQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRR 391
Score = 33.9 bits (76), Expect = 0.34
Identities = 25/115 (21%), Positives = 45/115 (39%), Gaps = 9/115 (7%)
Query: 363 RRERMGHHDDYYSRLRGRRNPSPDHSYKRNGESERKSSRHRGKKSHKRTSKSRERHNSR- 421
RRE+ + R + R + +++ E ER+ R + ++ +R RE R
Sbjct: 408 RREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERH 467
Query: 422 -SRGRNRDRSRDRSRGRGSR-------SRSRSRSRRSRRSRSQSSSRSRSRGRRR 468
R + RD+ R R R + RR ++ R + R R +R+
Sbjct: 468 EQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQ 522
Score = 31.2 bits (69), Expect = 2.2
Identities = 30/131 (22%), Positives = 50/131 (38%), Gaps = 10/131 (7%)
Query: 359 KNSERRERMGHHDDYYSRLRGRRNPSPDHSYKRNGESERKSSRHRGKKSHKRTSKSRERH 418
+ ERRE+ + RL+ R R + ER+ + ++ + + RE+
Sbjct: 510 EQEERREQRLKRQEEEERLQQRLR---SEQQLRREQEERREQLLKREEEKRLEQERREQR 566
Query: 419 NSRSRGRNRD----RSRDRSRGRGSR---SRSRSRSRRSRRSRSQSSSRSRSRGRRRSGN 471
R + RD R +R + R R R R +R R + R R +R
Sbjct: 567 LKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPE 626
Query: 472 RDRTVQSPKSK 482
+R Q KS+
Sbjct: 627 EERRQQLLKSE 637
Score = 30.4 bits (67), Expect = 3.7
Identities = 28/119 (23%), Positives = 42/119 (35%), Gaps = 7/119 (5%)
Query: 359 KNSERRERMGHHDDYYSRLRGRRNPSPDHSYKRNGESERKSSRHRGKKSHKRTSKSRERH 418
+ ER E+ + RL+ + D KR E+ER R K+ KR + R
Sbjct: 429 QEEERHEQKHEQERREQRLKREQEERRDW-LKREEETERHEQERR-KQQLKRDQEEERRE 486
Query: 419 -----NSRSRGRNRDRSRDRSRGRGSRSRSRSRSRRSRRSRSQSSSRSRSRGRRRSGNR 472
R ++R + R R + R+ R Q RS + RR R
Sbjct: 487 RWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEER 545
Score = 30.0 bits (66), Expect = 4.9
Identities = 23/114 (20%), Positives = 46/114 (40%), Gaps = 1/114 (0%)
Query: 362 ERRERMGHHDDYYSRLRGRRNPSPDHSYKRNGESERKSSRHRGKKSHKRTSKSRERHNSR 421
+ RER ++ R R + + E ++ + R +K + + R + R
Sbjct: 1442 QERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDR 1501
Query: 422 SRGRNRDRSRDRSRGRGSRSRSRSRSRRSRRS-RSQSSSRSRSRGRRRSGNRDR 474
RS++ R + R +R R+ + + R + RG++R +RDR
Sbjct: 1502 KFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDR 1555
Score = 29.3 bits (64), Expect = 8.3
Identities = 23/114 (20%), Positives = 46/114 (40%), Gaps = 6/114 (5%)
Query: 359 KNSERRERMGHHDDYYSRLRGRRNPSPDHSYKRNGESERKSSRHRGKKSHKRTSKSRERH 418
+ ERR+ + ++ + RR KR+ E ER+ + ++ +R + +ER
Sbjct: 450 EQEERRDWLKREEETERHEQERRK----QQLKRDQEEERRERWLKLEEEERR--EQQERR 503
Query: 419 NSRSRGRNRDRSRDRSRGRGSRSRSRSRSRRSRRSRSQSSSRSRSRGRRRSGNR 472
+ R +R R + + R + R R ++ R + R +R R
Sbjct: 504 EQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKR 557
Score = 29.3 bits (64), Expect = 8.3
Identities = 25/108 (23%), Positives = 45/108 (41%), Gaps = 7/108 (6%)
Query: 362 ERRERMGHHDDYYSRLRGRRNPSPDHSYKRNGESERKSSRHRGKKSHKRTSKSRERHNSR 421
E++ER + + R R P + + E+K ++ R +KS + RE +
Sbjct: 1273 EQQERDREQERRRWQQRDRHFPEEEQLERE----EQKEAKRRDRKSQEEKQLLREEREEK 1328
Query: 422 SRGRNRDRSRDRSRGRGSRSRSRSRSRRSRRSRS--QSSSRSRSRGRR 467
R + DR + R + + R RR R R + R + +GR+
Sbjct: 1329 RRRQETDR-KFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRK 1375
>gi|47271443 splicing factor, arginine/serine-rich 2 [Homo sapiens]
Length = 221
Score = 72.8 bits (177), Expect = 7e-13
Identities = 47/96 (48%), Positives = 60/96 (62%), Gaps = 5/96 (5%)
Query: 385 PDHSYKRNGESERK---SSRHRGKKSHKRTSKSRERHNSRSRGRNRDR-SRDRSRGR-GS 439
PD + R G R+ R +S +R +SR R SRSR R+R R SR +SR R S
Sbjct: 96 PDSHHSRRGPPPRRYGGGGYGRRSRSPRRRRRSRSRSRSRSRSRSRSRYSRSKSRSRTRS 155
Query: 440 RSRSRSRSRRSRRSRSQSSSRSRSRGRRRSGNRDRT 475
RSRS S+SR +RRS+S+SSS SRSR R RS +R R+
Sbjct: 156 RSRSTSKSRSARRSKSKSSSVSRSRSRSRSRSRSRS 191
Score = 57.0 bits (136), Expect = 4e-08
Identities = 70/251 (27%), Positives = 98/251 (39%), Gaps = 55/251 (21%)
Query: 232 TYQQFLDFYEDVLPEFKNVGKVIQFKVSCNLEPHLRGNVYVQYQSEEECQAALSLFNGRW 291
TY+ D V ++ VG V + E RG +V++ + + + A+ +G
Sbjct: 22 TYRTSPDTLRRVFEKYGRVGDVYIPRDRYTKES--RGFAFVRFHDKRDAEDAMDAMDGAV 79
Query: 292 YAGRQLQCEFCPVTRWKMAICGLFEIQQCPRGKHCNFLHVFRNPNNEFWEANRDIYLSPD 351
GR+L+ +Q G+ + H R P P
Sbjct: 80 LDGRELR------------------VQMARYGRPPDSHHSRRGP--------------PP 107
Query: 352 RT--GSSFGKNSE--RRERMGHHDDYYSRLRGRRNPSPDHSYKRNGESERKSSRHRGKKS 407
R G +G+ S RR R SR R R Y R+ R SR R
Sbjct: 108 RRYGGGGYGRRSRSPRRRRRSR-----SRSRSRSRSRSRSRYSRSKSRSRTRSRSRS--- 159
Query: 408 HKRTSKSRERHNSRSRGRNRDRSRDRSRGRGSRSRSRSRSRRSRRSRSQSSSRSRSRGRR 467
TSKSR S+S+ + RSR RSR SRSRSRS S+R +S SRSRS+
Sbjct: 160 ---TSKSRSARRSKSKSSSVSRSRSRSR---SRSRSRSPPPVSKR---ESKSRSRSKSPP 210
Query: 468 RSGNRDRTVQS 478
+S + V S
Sbjct: 211 KSPEEEGAVSS 221
>gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo
sapiens]
Length = 1293
Score = 72.4 bits (176), Expect = 9e-13
Identities = 42/142 (29%), Positives = 76/142 (53%), Gaps = 8/142 (5%)
Query: 25 EKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQLEEEKLLERERQRLHEEWLLREQKAQE 84
EK K + E R +++EEEE EE + ++E++L R+++ E+K +E
Sbjct: 724 EKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEE--------ERKRRE 775
Query: 85 EFRIKKEKEEAAKKRQEEQERKLKEQWEEQQRKEREEEEQKRQEKKEKEEALQKMLDQAE 144
E + + K+E A +RQ EQE L+ Q EE++R+++EE ++ +E++ +EE +K +
Sbjct: 776 EEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLR 835
Query: 145 NELENGTTWQNPEPPVDFRVME 166
+ E W E R+ E
Sbjct: 836 KQEEEAAKWAREEEEAQRRLEE 857
Score = 70.5 bits (171), Expect = 3e-12
Identities = 46/160 (28%), Positives = 91/160 (56%), Gaps = 25/160 (15%)
Query: 19 RAALKKEKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQLEEEKLLERER-QRLHEEWLL 77
R ++E++++ +ELAR + +++ E++ + Q+ EEE+ + E +RL E
Sbjct: 764 RRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRRE 823
Query: 78 REQKAQEEFRIKKEKEEAAK--KRQEEQERKLKE----QWEEQQRKEREEEEQKRQE--- 128
E++ ++E ++K++EEAAK + +EE +R+L+E EE R EEEE+KR+E
Sbjct: 824 EEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEV 883
Query: 129 ---------KKEKEEALQKMLDQ------AENELENGTTW 153
+++++EAL+++ Q A+ +L + +TW
Sbjct: 884 QRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTW 923
Score = 55.5 bits (132), Expect = 1e-07
Identities = 44/192 (22%), Positives = 92/192 (47%), Gaps = 48/192 (25%)
Query: 11 EKPSHKKYRAALKKEKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQLEEEKLLERERQR 70
E+ ++ AL++ + ++R +E R ++ L ++EEE + E++ E ++ LE R R
Sbjct: 803 EEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEE-EAQRRLEENRLR 861
Query: 71 LHEEWLL----REQKAQEEFRIKKEKEEAAKKRQEEQE--RKLKEQWEEQQ--------- 115
+ EE E++ ++E ++++KE ++RQ++QE R+L++Q ++QQ
Sbjct: 862 MEEEAARLRHEEEERKRKELEVQRQKE-LMRQRQQQQEALRRLQQQQQQQQLAQMKLPSS 920
Query: 116 ----------------------------RKEREEEEQKRQEKKEKEEALQKMLDQAENEL 147
+ER+ E++R++++E +ALQ+ Q + +L
Sbjct: 921 STWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKL 980
Query: 148 ENGTTWQNPEPP 159
W N P
Sbjct: 981 SG---WGNVSKP 989
Score = 50.8 bits (120), Expect = 3e-06
Identities = 30/87 (34%), Positives = 51/87 (58%), Gaps = 13/87 (14%)
Query: 56 QQLEEEKLLERERQRLHEEWLLREQKAQEEFRIKKEKEEAAKKRQEEQERKLKEQWEEQQ 115
QQLE+ K + E++R + E R K+E+EE +KRQEE R+ +E QQ
Sbjct: 721 QQLEKAKAAKLEQER-----------REAEMRAKREEEE--RKRQEELRRQQEEILRRQQ 767
Query: 116 RKEREEEEQKRQEKKEKEEALQKMLDQ 142
+ER+ E++ ++++EEAL++ +Q
Sbjct: 768 EEERKRREEEELARRKQEEALRRQREQ 794
Score = 39.7 bits (91), Expect = 0.006
Identities = 29/138 (21%), Positives = 76/138 (55%), Gaps = 14/138 (10%)
Query: 16 KKYRAALKKEKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQLEEEKLLERERQRLHEEW 75
++ + AL++ ++++++Q+LA+++ S ++ +T + Q L E Q+L EE
Sbjct: 894 QQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQAT---LSLAEIQKLEEE- 949
Query: 76 LLREQKAQEEFRIKKEKEEAAKKRQEEQERKLKEQWEEQQRK--------EREEEEQKRQ 127
RE++ +EE R ++ + A ++Q++Q+++ W + E ++EE ++
Sbjct: 950 --RERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQM 1007
Query: 128 EKKEKEEALQKMLDQAEN 145
+K+++++ + ++A N
Sbjct: 1008 QKQQQQQQQHQQPNRARN 1025
Score = 33.1 bits (74), Expect = 0.58
Identities = 21/57 (36%), Positives = 33/57 (57%), Gaps = 8/57 (14%)
Query: 100 QEEQERKLKEQWEEQQRKE------REEEEQKRQE--KKEKEEALQKMLDQAENELE 148
Q +Q K K EQ+R+E REEEE+KRQE ++++EE L++ ++ E
Sbjct: 719 QLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRRE 775
>gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo
sapiens]
Length = 1320
Score = 72.4 bits (176), Expect = 9e-13
Identities = 42/142 (29%), Positives = 76/142 (53%), Gaps = 8/142 (5%)
Query: 25 EKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQLEEEKLLERERQRLHEEWLLREQKAQE 84
EK K + E R +++EEEE EE + ++E++L R+++ E+K +E
Sbjct: 751 EKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEE--------ERKRRE 802
Query: 85 EFRIKKEKEEAAKKRQEEQERKLKEQWEEQQRKEREEEEQKRQEKKEKEEALQKMLDQAE 144
E + + K+E A +RQ EQE L+ Q EE++R+++EE ++ +E++ +EE +K +
Sbjct: 803 EEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLR 862
Query: 145 NELENGTTWQNPEPPVDFRVME 166
+ E W E R+ E
Sbjct: 863 KQEEEAAKWAREEEEAQRRLEE 884
Score = 70.5 bits (171), Expect = 3e-12
Identities = 46/160 (28%), Positives = 91/160 (56%), Gaps = 25/160 (15%)
Query: 19 RAALKKEKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQLEEEKLLERER-QRLHEEWLL 77
R ++E++++ +ELAR + +++ E++ + Q+ EEE+ + E +RL E
Sbjct: 791 RRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRRE 850
Query: 78 REQKAQEEFRIKKEKEEAAK--KRQEEQERKLKE----QWEEQQRKEREEEEQKRQE--- 128
E++ ++E ++K++EEAAK + +EE +R+L+E EE R EEEE+KR+E
Sbjct: 851 EEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEV 910
Query: 129 ---------KKEKEEALQKMLDQ------AENELENGTTW 153
+++++EAL+++ Q A+ +L + +TW
Sbjct: 911 QRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTW 950
Score = 55.5 bits (132), Expect = 1e-07
Identities = 44/192 (22%), Positives = 92/192 (47%), Gaps = 48/192 (25%)
Query: 11 EKPSHKKYRAALKKEKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQLEEEKLLERERQR 70
E+ ++ AL++ + ++R +E R ++ L ++EEE + E++ E ++ LE R R
Sbjct: 830 EEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEE-EAQRRLEENRLR 888
Query: 71 LHEEWLL----REQKAQEEFRIKKEKEEAAKKRQEEQE--RKLKEQWEEQQ--------- 115
+ EE E++ ++E ++++KE ++RQ++QE R+L++Q ++QQ
Sbjct: 889 MEEEAARLRHEEEERKRKELEVQRQKE-LMRQRQQQQEALRRLQQQQQQQQLAQMKLPSS 947
Query: 116 ----------------------------RKEREEEEQKRQEKKEKEEALQKMLDQAENEL 147
+ER+ E++R++++E +ALQ+ Q + +L
Sbjct: 948 STWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKL 1007
Query: 148 ENGTTWQNPEPP 159
W N P
Sbjct: 1008 SG---WGNVSKP 1016
Score = 50.8 bits (120), Expect = 3e-06
Identities = 30/87 (34%), Positives = 51/87 (58%), Gaps = 13/87 (14%)
Query: 56 QQLEEEKLLERERQRLHEEWLLREQKAQEEFRIKKEKEEAAKKRQEEQERKLKEQWEEQQ 115
QQLE+ K + E++R + E R K+E+EE +KRQEE R+ +E QQ
Sbjct: 748 QQLEKAKAAKLEQER-----------REAEMRAKREEEE--RKRQEELRRQQEEILRRQQ 794
Query: 116 RKEREEEEQKRQEKKEKEEALQKMLDQ 142
+ER+ E++ ++++EEAL++ +Q
Sbjct: 795 EEERKRREEEELARRKQEEALRRQREQ 821
Score = 39.7 bits (91), Expect = 0.006
Identities = 29/138 (21%), Positives = 76/138 (55%), Gaps = 14/138 (10%)
Query: 16 KKYRAALKKEKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQLEEEKLLERERQRLHEEW 75
++ + AL++ ++++++Q+LA+++ S ++ +T + Q L E Q+L EE
Sbjct: 921 QQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQAT---LSLAEIQKLEEE- 976
Query: 76 LLREQKAQEEFRIKKEKEEAAKKRQEEQERKLKEQWEEQQRK--------EREEEEQKRQ 127
RE++ +EE R ++ + A ++Q++Q+++ W + E ++EE ++
Sbjct: 977 --RERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQM 1034
Query: 128 EKKEKEEALQKMLDQAEN 145
+K+++++ + ++A N
Sbjct: 1035 QKQQQQQQQHQQPNRARN 1052
Score = 33.1 bits (74), Expect = 0.58
Identities = 21/57 (36%), Positives = 33/57 (57%), Gaps = 8/57 (14%)
Query: 100 QEEQERKLKEQWEEQQRKE------REEEEQKRQE--KKEKEEALQKMLDQAENELE 148
Q +Q K K EQ+R+E REEEE+KRQE ++++EE L++ ++ E
Sbjct: 746 QLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRRE 802
>gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo
sapiens]
Length = 1299
Score = 72.4 bits (176), Expect = 9e-13
Identities = 42/142 (29%), Positives = 76/142 (53%), Gaps = 8/142 (5%)
Query: 25 EKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQLEEEKLLERERQRLHEEWLLREQKAQE 84
EK K + E R +++EEEE EE + ++E++L R+++ E+K +E
Sbjct: 730 EKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEE--------ERKRRE 781
Query: 85 EFRIKKEKEEAAKKRQEEQERKLKEQWEEQQRKEREEEEQKRQEKKEKEEALQKMLDQAE 144
E + + K+E A +RQ EQE L+ Q EE++R+++EE ++ +E++ +EE +K +
Sbjct: 782 EEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLR 841
Query: 145 NELENGTTWQNPEPPVDFRVME 166
+ E W E R+ E
Sbjct: 842 KQEEEAAKWAREEEEAQRRLEE 863
Score = 70.5 bits (171), Expect = 3e-12
Identities = 46/160 (28%), Positives = 91/160 (56%), Gaps = 25/160 (15%)
Query: 19 RAALKKEKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQLEEEKLLERER-QRLHEEWLL 77
R ++E++++ +ELAR + +++ E++ + Q+ EEE+ + E +RL E
Sbjct: 770 RRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRRE 829
Query: 78 REQKAQEEFRIKKEKEEAAK--KRQEEQERKLKE----QWEEQQRKEREEEEQKRQE--- 128
E++ ++E ++K++EEAAK + +EE +R+L+E EE R EEEE+KR+E
Sbjct: 830 EEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEV 889
Query: 129 ---------KKEKEEALQKMLDQ------AENELENGTTW 153
+++++EAL+++ Q A+ +L + +TW
Sbjct: 890 QRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTW 929
Score = 55.5 bits (132), Expect = 1e-07
Identities = 44/192 (22%), Positives = 92/192 (47%), Gaps = 48/192 (25%)
Query: 11 EKPSHKKYRAALKKEKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQLEEEKLLERERQR 70
E+ ++ AL++ + ++R +E R ++ L ++EEE + E++ E ++ LE R R
Sbjct: 809 EEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEE-EAQRRLEENRLR 867
Query: 71 LHEEWLL----REQKAQEEFRIKKEKEEAAKKRQEEQE--RKLKEQWEEQQ--------- 115
+ EE E++ ++E ++++KE ++RQ++QE R+L++Q ++QQ
Sbjct: 868 MEEEAARLRHEEEERKRKELEVQRQKE-LMRQRQQQQEALRRLQQQQQQQQLAQMKLPSS 926
Query: 116 ----------------------------RKEREEEEQKRQEKKEKEEALQKMLDQAENEL 147
+ER+ E++R++++E +ALQ+ Q + +L
Sbjct: 927 STWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKL 986
Query: 148 ENGTTWQNPEPP 159
W N P
Sbjct: 987 SG---WGNVSKP 995
Score = 50.8 bits (120), Expect = 3e-06
Identities = 30/87 (34%), Positives = 51/87 (58%), Gaps = 13/87 (14%)
Query: 56 QQLEEEKLLERERQRLHEEWLLREQKAQEEFRIKKEKEEAAKKRQEEQERKLKEQWEEQQ 115
QQLE+ K + E++R + E R K+E+EE +KRQEE R+ +E QQ
Sbjct: 727 QQLEKAKAAKLEQER-----------REAEMRAKREEEE--RKRQEELRRQQEEILRRQQ 773
Query: 116 RKEREEEEQKRQEKKEKEEALQKMLDQ 142
+ER+ E++ ++++EEAL++ +Q
Sbjct: 774 EEERKRREEEELARRKQEEALRRQREQ 800
Score = 39.7 bits (91), Expect = 0.006
Identities = 29/138 (21%), Positives = 76/138 (55%), Gaps = 14/138 (10%)
Query: 16 KKYRAALKKEKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQLEEEKLLERERQRLHEEW 75
++ + AL++ ++++++Q+LA+++ S ++ +T + Q L E Q+L EE
Sbjct: 900 QQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQAT---LSLAEIQKLEEE- 955
Query: 76 LLREQKAQEEFRIKKEKEEAAKKRQEEQERKLKEQWEEQQRK--------EREEEEQKRQ 127
RE++ +EE R ++ + A ++Q++Q+++ W + E ++EE ++
Sbjct: 956 --RERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQM 1013
Query: 128 EKKEKEEALQKMLDQAEN 145
+K+++++ + ++A N
Sbjct: 1014 QKQQQQQQQHQQPNRARN 1031
Score = 33.1 bits (74), Expect = 0.58
Identities = 21/57 (36%), Positives = 33/57 (57%), Gaps = 8/57 (14%)
Query: 100 QEEQERKLKEQWEEQQRKE------REEEEQKRQE--KKEKEEALQKMLDQAENELE 148
Q +Q K K EQ+R+E REEEE+KRQE ++++EE L++ ++ E
Sbjct: 725 QLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRRE 781
>gi|42476299 GRB10 interacting GYF protein 2 isoform b [Homo
sapiens]
Length = 1299
Score = 72.4 bits (176), Expect = 9e-13
Identities = 42/142 (29%), Positives = 76/142 (53%), Gaps = 8/142 (5%)
Query: 25 EKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQLEEEKLLERERQRLHEEWLLREQKAQE 84
EK K + E R +++EEEE EE + ++E++L R+++ E+K +E
Sbjct: 730 EKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEE--------ERKRRE 781
Query: 85 EFRIKKEKEEAAKKRQEEQERKLKEQWEEQQRKEREEEEQKRQEKKEKEEALQKMLDQAE 144
E + + K+E A +RQ EQE L+ Q EE++R+++EE ++ +E++ +EE +K +
Sbjct: 782 EEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLR 841
Query: 145 NELENGTTWQNPEPPVDFRVME 166
+ E W E R+ E
Sbjct: 842 KQEEEAAKWAREEEEAQRRLEE 863
Score = 70.5 bits (171), Expect = 3e-12
Identities = 46/160 (28%), Positives = 91/160 (56%), Gaps = 25/160 (15%)
Query: 19 RAALKKEKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQLEEEKLLERER-QRLHEEWLL 77
R ++E++++ +ELAR + +++ E++ + Q+ EEE+ + E +RL E
Sbjct: 770 RRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRRE 829
Query: 78 REQKAQEEFRIKKEKEEAAK--KRQEEQERKLKE----QWEEQQRKEREEEEQKRQE--- 128
E++ ++E ++K++EEAAK + +EE +R+L+E EE R EEEE+KR+E
Sbjct: 830 EEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEV 889
Query: 129 ---------KKEKEEALQKMLDQ------AENELENGTTW 153
+++++EAL+++ Q A+ +L + +TW
Sbjct: 890 QRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTW 929
Score = 55.5 bits (132), Expect = 1e-07
Identities = 44/192 (22%), Positives = 92/192 (47%), Gaps = 48/192 (25%)
Query: 11 EKPSHKKYRAALKKEKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQLEEEKLLERERQR 70
E+ ++ AL++ + ++R +E R ++ L ++EEE + E++ E ++ LE R R
Sbjct: 809 EEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEE-EAQRRLEENRLR 867
Query: 71 LHEEWLL----REQKAQEEFRIKKEKEEAAKKRQEEQE--RKLKEQWEEQQ--------- 115
+ EE E++ ++E ++++KE ++RQ++QE R+L++Q ++QQ
Sbjct: 868 MEEEAARLRHEEEERKRKELEVQRQKE-LMRQRQQQQEALRRLQQQQQQQQLAQMKLPSS 926
Query: 116 ----------------------------RKEREEEEQKRQEKKEKEEALQKMLDQAENEL 147
+ER+ E++R++++E +ALQ+ Q + +L
Sbjct: 927 STWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKL 986
Query: 148 ENGTTWQNPEPP 159
W N P
Sbjct: 987 SG---WGNVSKP 995
Score = 50.8 bits (120), Expect = 3e-06
Identities = 30/87 (34%), Positives = 51/87 (58%), Gaps = 13/87 (14%)
Query: 56 QQLEEEKLLERERQRLHEEWLLREQKAQEEFRIKKEKEEAAKKRQEEQERKLKEQWEEQQ 115
QQLE+ K + E++R + E R K+E+EE +KRQEE R+ +E QQ
Sbjct: 727 QQLEKAKAAKLEQER-----------REAEMRAKREEEE--RKRQEELRRQQEEILRRQQ 773
Query: 116 RKEREEEEQKRQEKKEKEEALQKMLDQ 142
+ER+ E++ ++++EEAL++ +Q
Sbjct: 774 EEERKRREEEELARRKQEEALRRQREQ 800
Score = 39.7 bits (91), Expect = 0.006
Identities = 29/138 (21%), Positives = 76/138 (55%), Gaps = 14/138 (10%)
Query: 16 KKYRAALKKEKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQLEEEKLLERERQRLHEEW 75
++ + AL++ ++++++Q+LA+++ S ++ +T + Q L E Q+L EE
Sbjct: 900 QQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQAT---LSLAEIQKLEEE- 955
Query: 76 LLREQKAQEEFRIKKEKEEAAKKRQEEQERKLKEQWEEQQRK--------EREEEEQKRQ 127
RE++ +EE R ++ + A ++Q++Q+++ W + E ++EE ++
Sbjct: 956 --RERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQM 1013
Query: 128 EKKEKEEALQKMLDQAEN 145
+K+++++ + ++A N
Sbjct: 1014 QKQQQQQQQHQQPNRARN 1031
Score = 33.1 bits (74), Expect = 0.58
Identities = 21/57 (36%), Positives = 33/57 (57%), Gaps = 8/57 (14%)
Query: 100 QEEQERKLKEQWEEQQRKE------REEEEQKRQE--KKEKEEALQKMLDQAENELE 148
Q +Q K K EQ+R+E REEEE+KRQE ++++EE L++ ++ E
Sbjct: 725 QLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRRE 781
>gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]
Length = 2817
Score = 72.0 bits (175), Expect = 1e-12
Identities = 48/133 (36%), Positives = 83/133 (62%), Gaps = 9/133 (6%)
Query: 21 ALKKEKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQLEEEKLLERERQRLHEEWLLREQ 80
A K+ + ++RR E R K +E I E+Q E++ ERER++ E RE+
Sbjct: 462 ARKRREEEERRMEEQRKAACAEKLKRLDEKLGILEKQPSPEEIREREREKERE----REK 517
Query: 81 KAQEEFRIKKEKE-EAAKKRQEEQERKLKEQWEEQQRKEREEEEQKRQE---KKEKEEAL 136
+ ++E ++EKE E ++RQ+E+E++L+++ E+Q+ E+E +++K +E +KEKE+ L
Sbjct: 518 ELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQREMEKERKQEKEKELERQKEKEKEL 577
Query: 137 QKMLDQ-AENELE 148
QKM +Q E ELE
Sbjct: 578 QKMKEQEKECELE 590
Score = 66.2 bits (160), Expect = 6e-11
Identities = 48/145 (33%), Positives = 90/145 (62%), Gaps = 20/145 (13%)
Query: 5 EKMTFPEK-PSHKKYRAALKKEKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQLEEEKL 63
EK+ EK PS ++ R ++EK ++R +EL +KE +EQ+ E+E+
Sbjct: 490 EKLGILEKQPSPEEIRER-EREKEREREKEL---------EKE-------QEQEREKERE 532
Query: 64 LERERQRLHEEWLLREQKAQEEF-RIKKEKEEAAKKRQEEQERKLKEQWEEQQRKEREEE 122
+RERQ+ E+ L +EQ+ Q E + +K+++E +RQ+E+E++L++ E+++ E E+E
Sbjct: 533 KDRERQQEKEKELEKEQEKQREMEKERKQEKEKELERQKEKEKELQKMKEQEKECELEKE 592
Query: 123 EQKRQEKKE-KEEALQKMLDQAENE 146
+K +EK E +E L+ M+++ E+E
Sbjct: 593 REKLEEKIEPREPNLEPMVEKQESE 617
Score = 36.2 bits (82), Expect = 0.068
Identities = 17/102 (16%), Positives = 47/102 (46%), Gaps = 5/102 (4%)
Query: 381 RNPSPDHSYKRNGESERKSSRHRGKKSHKRTSKSRERHNSRSRGRNRDRSRDRSRGRGSR 440
+ PSP+ +R ER+ R R K+ K + RE+ + R R +++ ++ + + +
Sbjct: 497 KQPSPEEIRER----EREKEREREKELEKEQEQEREKEREKDRERQQEKEKELEKEQ-EK 551
Query: 441 SRSRSRSRRSRRSRSQSSSRSRSRGRRRSGNRDRTVQSPKSK 482
R + R+ + + + + + ++ +++ + K +
Sbjct: 552 QREMEKERKQEKEKELERQKEKEKELQKMKEQEKECELEKER 593
Score = 35.8 bits (81), Expect = 0.089
Identities = 31/169 (18%), Positives = 73/169 (43%), Gaps = 13/169 (7%)
Query: 3 APEKMTFPEKPSHKKYRAALKKEKRKKRRQELARLRDSGLSQKEEEEDTF--IEEQQLEE 60
AP++ T P ++ A + RK+ + Q+ E + + ++
Sbjct: 898 APDQKTL-SAPQEERISAVESQPSRKRSVSHGSNHTQKPDEQRSEPSAGIPKVTSRCIDS 956
Query: 61 EKLLERERQRLHEEWLLREQKAQEEFRIKKEKEE-------AAKKRQEEQERKLKEQWEE 113
++ +ER ++ +E +R + + ++ K K E ++ +R+E +R ++
Sbjct: 957 KEPIERPEEKPKKEGFIRSSEGPKPEKVYKSKSETRWGPRPSSNRREEVNDRPVRRSGPI 1016
Query: 114 QQ---RKEREEEEQKRQEKKEKEEALQKMLDQAENELENGTTWQNPEPP 159
++ R +EE EQ+++++ EK E + + + + E P PP
Sbjct: 1017 KKPVLRDMKEEREQRKEKEGEKAEKVTEKVVVKPEKTEKKDLPPPPPPP 1065
Score = 34.7 bits (78), Expect = 0.20
Identities = 30/158 (18%), Positives = 66/158 (41%), Gaps = 51/158 (32%)
Query: 11 EKPSHKKYRAALKKEKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQLEEEKLLERERQR 70
E+ K+ ++EK+++ +E + ++ L +++E+E + ++ E+E LE+ER++
Sbjct: 536 ERQQEKEKELEKEQEKQREMEKERKQEKEKELERQKEKEKELQKMKEQEKECELEKEREK 595
Query: 71 LHEEWLLRE-------QKAQEEFRIKKEKEEAAKKR------------------------ 99
L E+ RE +K + E KE+E ++
Sbjct: 596 LEEKIEPREPNLEPMVEKQESENSCNKEEEPVFTRQDSNRSEKEATPVVHETEPESGSQP 655
Query: 100 --------------------QEEQERKLKEQWEEQQRK 117
Q +QE+ ++QW++QQ++
Sbjct: 656 RPAVLSGYFKQFQKSLPPRFQRQQEQMKQQQWQQQQQQ 693
Score = 31.6 bits (70), Expect = 1.7
Identities = 29/140 (20%), Positives = 50/140 (35%), Gaps = 11/140 (7%)
Query: 335 PNNEFWEANRDIYLSPDRTGSSFGKNSERRERMGHHDDYYSRLRGRRNPSPDHSYKRNGE 394
P +W+ R+ PD+ G+ + Y R RG R + D+ R+
Sbjct: 1166 PPRTYWKEARERDWFPDQGYRGRGRGEYYSRGRSYRGSYGGRGRGGRGHTRDYPQYRD-- 1223
Query: 395 SERKSSRHRGKKSHKRTSKSRERHNSRSRGRNRDRS--RDRSRGRGSRSRSRSRSRRSRR 452
++ + H + R+R S +R + D R R RGS + + S S
Sbjct: 1224 -------NKPRAEHIPSGPLRQREESETRSESSDFEVVPKRRRQRGSETDTDSEIHESAS 1276
Query: 453 SRSQSSSRSRSRGRRRSGNR 472
+ S + R N+
Sbjct: 1277 DKDSLSKGKLPKREERPENK 1296
>gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo
sapiens]
Length = 1031
Score = 71.6 bits (174), Expect = 1e-12
Identities = 51/118 (43%), Positives = 65/118 (55%), Gaps = 10/118 (8%)
Query: 367 MGHHDDYYSRLRGRRNPSPDHSYKRNGESERKSSRHRGKKSHKRTSKSRERHNSRSRGRN 426
MG +Y + R S S R+ S+++S R ++S S+ R+R RSR R+
Sbjct: 1 MGRESRHYRKRSASRGRSGSRSRSRS-PSDKRSKRGDDRRSR---SRDRDRRRERSRSRD 56
Query: 427 --RDRSRDRSRGRGSRSRSRSRSRRSRRSRSQSSSRSRSRGRRRSGNRDRTVQSPKSK 482
R RSRDR R R SRSR R RSR RRSRS+ RSRSR R G R R+ SP +K
Sbjct: 57 KRRSRSRDRKRLRRSRSRERDRSRERRRSRSRDRRRSRSRSR---GRRSRS-SSPGNK 110
Score = 70.1 bits (170), Expect = 4e-12
Identities = 44/127 (34%), Positives = 68/127 (53%), Gaps = 6/127 (4%)
Query: 349 SPDRTGSSFGKNSERRERMGHHDDYYSRLRGRRNPSPDHSYKRNGESERKSSRHRGKKSH 408
S R+GS S +R DD SR R R D +R+ +++ SR R +K
Sbjct: 14 SRGRSGSRSRSRSPSDKRSKRGDDRRSRSRDR-----DRRRERSRSRDKRRSRSRDRKRL 68
Query: 409 KRT-SKSRERHNSRSRGRNRDRSRDRSRGRGSRSRSRSRSRRSRRSRSQSSSRSRSRGRR 467
+R+ S+ R+R R R R+RDR R RSR RG RSRS S +S+++ ++S S+ ++ G
Sbjct: 69 RRSRSRERDRSRERRRSRSRDRRRSRSRSRGRRSRSSSPGNKSKKTENRSRSKEKTDGGE 128
Query: 468 RSGNRDR 474
S + +
Sbjct: 129 SSKEKKK 135
Score = 39.3 bits (90), Expect = 0.008
Identities = 30/152 (19%), Positives = 68/152 (44%), Gaps = 11/152 (7%)
Query: 13 PSHKKYRAALKKEKRKK---RRQELARLRDSGLSQKEEEEDTFIEEQQLEEEKLLERERQ 69
PS K+ + + R + RR+E +R RD S+ + + + E ++ ER R
Sbjct: 27 PSDKRSKRGDDRRSRSRDRDRRRERSRSRDKRRSRSRDRK-RLRRSRSRERDRSRERRRS 85
Query: 70 RLHEEWLLREQKAQEEFRIKKEKEEAAKKRQEEQERKLKEQWEE-QQRKEREEEEQKRQE 128
R + R +++ R + K ++ E + KE+ + + KE+++++ +++
Sbjct: 86 RSRDR---RRSRSRSRGRRSRSSSPGNKSKKTENRSRSKEKTDGGESSKEKKKDKDDKED 142
Query: 129 KKEKEEA---LQKMLDQAENELENGTTWQNPE 157
+KEK+ K+ ++ E W+ +
Sbjct: 143 EKEKDAGNFDQNKLEEEMRKRKERVEKWREEQ 174
Score = 38.1 bits (87), Expect = 0.018
Identities = 30/138 (21%), Positives = 62/138 (44%), Gaps = 5/138 (3%)
Query: 16 KKYRAALKKEKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQLEEEKLLERERQRLHEEW 75
K+ R + +E+ + R + +R RD S+ + K E R R E+
Sbjct: 66 KRLRRSRSRERDRSRERRRSRSRDRRRSRSRSRGRRSRSSSPGNKSKKTEN-RSRSKEKT 124
Query: 76 LLREQKAQEEFRIKKEKEEAAKKRQEEQERKLKEQWEEQQRKEREEEEQKRQEKKEKEEA 135
E ++ KK+K++ +++++ + + EE+ RK +E E+ R+E+++K
Sbjct: 125 DGGESSKEK----KKDKDDKEDEKEKDAGNFDQNKLEEEMRKRKERVEKWREEQRKKAME 180
Query: 136 LQKMLDQAENELENGTTW 153
L + E++ G W
Sbjct: 181 NIGELKKEIEEMKQGKKW 198
Score = 38.1 bits (87), Expect = 0.018
Identities = 34/139 (24%), Positives = 63/139 (45%), Gaps = 12/139 (8%)
Query: 10 PEKPSHKKYRAALKKEKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQLEEEKLLERERQ 69
P S K + KEK + +D + E+E+D +Q EE++ R+R+
Sbjct: 107 PGNKSKKTENRSRSKEKTDGGESSKEKKKDKDDKEDEKEKDAGNFDQNKLEEEM--RKRK 164
Query: 70 RLHEEWLLREQKAQEEFRIKKEKEEAAKKRQEEQERKLKEQWEEQQRKEREEEEQKRQEK 129
E+W +EE R KK E + ++E +E K ++W + + ++E+ + +
Sbjct: 165 ERVEKW-------REEQR-KKAMENIGELKKEIEEMKQGKKWSLED--DDDDEDDPAEAE 214
Query: 130 KEKEEALQKMLDQAENELE 148
KE E + LD + +E
Sbjct: 215 KEGNEMEGEELDPLDAYME 233
Score = 37.7 bits (86), Expect = 0.023
Identities = 52/229 (22%), Positives = 95/229 (41%), Gaps = 26/229 (11%)
Query: 16 KKYRAALKKEKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQLEEEKLLERERQRLHEEW 75
++ R+ ++ R + R +R G K+ E + +E+ E E+++ + +E
Sbjct: 83 RRSRSRDRRRSRSRSRGRRSRSSSPGNKSKKTENRSRSKEKTDGGESSKEKKKDKDDKE- 141
Query: 76 LLREQKAQEEFRIKKEK-EEAAKKRQEEQERKLKEQWEEQQRK---------EREEEEQK 125
++K ++ + K EE +KR+E E+ W E+QRK ++E EE K
Sbjct: 142 ---DEKEKDAGNFDQNKLEEEMRKRKERVEK-----WREEQRKKAMENIGELKKEIEEMK 193
Query: 126 RQEKKEKEEALQKMLDQAENELENGTTWQNPEPPVDFRVMEKDRANCPFYSKTGACRFGD 185
+ +K E+ D AE E E P+D + E F ++ G
Sbjct: 194 QGKKWSLEDDDDDEDDPAEAEKEGNEMEGEELDPLDAYMEEVKEEVKKFNMRSVK---GG 250
Query: 186 RCSRKHNFPTSSPTLLI---KSMFTTFGMEQCRRDDYDPDASLEYSEEE 231
+ K + PT + + + K ++ + D DA +EYS EE
Sbjct: 251 GGNEKKSGPTVTKVVTVVTTKKAVVDSDKKKGELMENDQDA-MEYSSEE 298
Score = 34.3 bits (77), Expect = 0.26
Identities = 22/146 (15%), Positives = 61/146 (41%), Gaps = 2/146 (1%)
Query: 24 KEKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQLEEEKLLERERQRLHEEWLLREQKAQ 83
+E R R++ +R R S+ D ++ ++ + R+R R E R+++
Sbjct: 3 RESRHYRKRSASRGRSGSRSRSRSPSDK--RSKRGDDRRSRSRDRDRRRERSRSRDKRRS 60
Query: 84 EEFRIKKEKEEAAKKRQEEQERKLKEQWEEQQRKEREEEEQKRQEKKEKEEALQKMLDQA 143
K+ + +++R +ER+ + ++ + R + R + + ++
Sbjct: 61 RSRDRKRLRRSRSRERDRSRERRRSRSRDRRRSRSRSRGRRSRSSSPGNKSKKTENRSRS 120
Query: 144 ENELENGTTWQNPEPPVDFRVMEKDR 169
+ + + G + + + D + EK++
Sbjct: 121 KEKTDGGESSKEKKKDKDDKEDEKEK 146
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 70.9 bits (172), Expect = 2e-12
Identities = 45/159 (28%), Positives = 89/159 (55%), Gaps = 10/159 (6%)
Query: 5 EKMTFPEKPSHKKYRAALKKEKRKKRRQELARLRDSGLSQKEE------EEDTFIEEQQL 58
EK+ E+ ++ +KE++ +R++E+ ++ + ++EE E+ +EE+
Sbjct: 389 EKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMH 448
Query: 59 EEEKLLERERQRLHEEWLLREQKAQEEFRIKKEKEEAAKKRQEEQERKLKEQWEEQQRKE 118
E+EK+ E+E +R EE +REQ+ ++E K ++E ++ EQE K++EQ E+ R+E
Sbjct: 449 EQEKIREQEEKRQEEE-KIREQEKRQEQEAKMWRQE---EKIREQEEKIREQEEKMWRQE 504
Query: 119 REEEEQKRQEKKEKEEALQKMLDQAENELENGTTWQNPE 157
+ EQ++ ++EK + ++M Q E E W+ E
Sbjct: 505 EKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKE 543
Score = 67.8 bits (164), Expect = 2e-11
Identities = 45/147 (30%), Positives = 84/147 (57%), Gaps = 5/147 (3%)
Query: 5 EKMTFPEKPSHKKYRAALKKEKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQLEEEKLL 64
EKM E+ H + ++E++ R++E R ++ + ++EE+ E Q +EEK+
Sbjct: 557 EKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMG 616
Query: 65 ERERQRLHEEWLLREQKAQEEFRIKKEKEEAAKKRQEEQERKLKEQWE---EQQRKEREE 121
E+E + +E ++EQ +E+ R ++EK +K+ EQE K++EQ E EQ+ K E+
Sbjct: 617 EQEEKMCEQEEKMQEQ--EEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQ 674
Query: 122 EEQKRQEKKEKEEALQKMLDQAENELE 148
EE+ +++++ +E +KM Q E E
Sbjct: 675 EEKMCEQEEKMQEQEEKMRRQEEKMWE 701
Score = 67.4 bits (163), Expect = 3e-11
Identities = 43/141 (30%), Positives = 84/141 (59%), Gaps = 8/141 (5%)
Query: 22 LKKEKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQL--EEEKLLERERQRLHEEWLLRE 79
++K++ K RQE ++ D +E+EE + +E+++ +EEK+ E+E + +E + +E
Sbjct: 552 IRKQEEKMWRQE-EKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQE 610
Query: 80 QKAQEEFRIKKEKEEAAKKRQEEQERKLKEQWE---EQQRKEREEEEQKRQEKKEKEEAL 136
Q +E+ ++EK +++ +EQE K++ Q E EQ++K RE+EE+ R++++ +E
Sbjct: 611 Q--EEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQE 668
Query: 137 QKMLDQAENELENGTTWQNPE 157
+KM +Q E E Q E
Sbjct: 669 EKMWEQEEKMCEQEEKMQEQE 689
Score = 64.3 bits (155), Expect = 2e-10
Identities = 53/189 (28%), Positives = 95/189 (50%), Gaps = 36/189 (19%)
Query: 5 EKMTFPEK---PSHKKYRAALKKEKRKKRRQELA------RLRDSGLSQKEEEEDTFIEE 55
EKM EK K+ +E+ K++ QE ++R+ +E+EE + +E
Sbjct: 445 EKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQE 504
Query: 56 QQL-EEEKLLERERQRLHEEWLLREQKAQEEFRIKKEKE------EAAKKRQE------- 101
+++ E+EK+ E E+++ EE +E+K +E+ I ++KE E +K++E
Sbjct: 505 EKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEE 564
Query: 102 ---EQERKLKEQWE----------EQQRKEREEEEQKRQEKKEKEEALQKMLDQAENELE 148
+QE K++EQ E EQ+ K RE+EE+ R++++ +E +KM +Q E E
Sbjct: 565 KMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCE 624
Query: 149 NGTTWQNPE 157
Q E
Sbjct: 625 QEEKMQEQE 633
Score = 63.2 bits (152), Expect = 5e-10
Identities = 35/149 (23%), Positives = 86/149 (57%), Gaps = 15/149 (10%)
Query: 23 KKEKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQLEEEKLLERERQRLHEE-------- 74
K +++++ E ++R+ +++E+E+ + +E+++ E++ + R+++++HE+
Sbjct: 499 KMWRQEEKIHEQEKIREE--EKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQE 556
Query: 75 ---WLLREQKAQEEFRIKKEKEEAAKKRQEEQERKLKEQWEEQQRKEREEEEQKRQEKKE 131
W E+ +E +I++++E+ RQEE+ R+ +E+ EQ+ K RE+EE ++++++
Sbjct: 557 EKMWRQEEKMHDQEEKIREQEEKVW--RQEEKIREQEEKIREQEEKIREQEEMTQEQEEK 614
Query: 132 KEEALQKMLDQAENELENGTTWQNPEPPV 160
E +KM +Q E E + E +
Sbjct: 615 MGEQEEKMCEQEEKMQEQEEKMRRQEEKI 643
Score = 62.0 bits (149), Expect = 1e-09
Identities = 45/158 (28%), Positives = 88/158 (55%), Gaps = 15/158 (9%)
Query: 5 EKMTFPEKPSHKKYRAALKKEKRK---KRRQELARLRDSGLSQKEEEEDTFIEEQQLEEE 61
EK+ E+ H++ + ++EKR+ K R++ R ++EE+ EE+ E+E
Sbjct: 438 EKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQE 497
Query: 62 KLLERERQRLHEEWLLREQKAQEEFRIKKEKEEAAKKRQEEQERKLKEQWEEQQR-KERE 120
+ + R+ +++HE+ +RE+ +K +E+ RQEE+ R+ +E W ++++ E+E
Sbjct: 498 EKMWRQEEKIHEQEKIREE--------EKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQE 549
Query: 121 EEEQKRQEKKEKEEALQKMLDQAENELE-NGTTWQNPE 157
E+ +K++EK ++E +KM DQ E E W+ E
Sbjct: 550 EKIRKQEEKMWRQE--EKMHDQEEKIREQEEKVWRQEE 585
Score = 61.2 bits (147), Expect = 2e-09
Identities = 44/154 (28%), Positives = 90/154 (58%), Gaps = 14/154 (9%)
Query: 5 EKMTFPEKPSHKKYRAALKKEKRKKRRQELARLRDSGLSQKE----EEEDTFIEEQQL-- 58
E+ E+ ++ ++E++ + ++E+ R ++ Q+E +EE + +E+++
Sbjct: 509 EQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHD 568
Query: 59 EEEKLLERERQRLHEEWLLREQ--KAQEEFRIKKEKEEAAKKRQE---EQERKLKEQWE- 112
+EEK+ E+E + +E +REQ K +E+ +E+EE ++++E EQE K+ EQ E
Sbjct: 569 QEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEK 628
Query: 113 --EQQRKEREEEEQKRQEKKEKEEALQKMLDQAE 144
EQ+ K R +EE+ R+++K+ E +K+ +Q E
Sbjct: 629 MQEQEEKMRRQEEKIREQEKKIREQEEKIREQEE 662
Score = 60.8 bits (146), Expect = 3e-09
Identities = 38/131 (29%), Positives = 79/131 (60%), Gaps = 7/131 (5%)
Query: 24 KEKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQL--EEEKLLERERQRLHEEWLLREQK 81
+E+ +K R++ ++R+ +E+EE +E+++ +EEK+ E+E + +E +REQ
Sbjct: 588 REQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQ- 646
Query: 82 AQEEFRIKKEKEEAAKKRQEEQERKLKEQWE---EQQRKEREEEEQKRQEKKEKEEALQK 138
+++ R ++EK ++ +EQE K+ EQ E EQ+ K +E+EE+ R+++++ E +
Sbjct: 647 -EKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVR 705
Query: 139 MLDQAENELEN 149
+ Q E E+
Sbjct: 706 LRQQEEKMQEH 716
Score = 60.5 bits (145), Expect = 3e-09
Identities = 39/146 (26%), Positives = 88/146 (60%), Gaps = 7/146 (4%)
Query: 5 EKMTFPEKPSHKKYRAALKKEKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQLEEEKLL 64
EK+ E+ ++ ++E++ + ++E+ + ++ + ++EE+ E+ Q +EEK+
Sbjct: 578 EKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMR 637
Query: 65 ERERQRLHEEWLLREQ--KAQEEFRIKKEKEEAAKKRQE---EQERKLKEQWEEQQRKER 119
+E + +E +REQ K +E+ + +E+EE +++E EQE K++EQ E+ +R+E
Sbjct: 638 RQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEE 697
Query: 120 E--EEEQKRQEKKEKEEALQKMLDQA 143
+ E+E + ++++EK + Q+ L+ A
Sbjct: 698 KMWEQEVRLRQQEEKMQEHQEHLEAA 723
Score = 58.2 bits (139), Expect = 2e-08
Identities = 35/156 (22%), Positives = 86/156 (55%), Gaps = 3/156 (1%)
Query: 5 EKMTFPEKPSHKKYRAALKKEKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQLEEEKLL 64
EK+ E+ ++ ++E++ +R++E+ ++ + ++EE E+ + +EE +
Sbjct: 375 EKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMW 434
Query: 65 ERERQRLHEEWLLREQKAQEEFRIKKEKEEAAKKRQEEQERKLKEQWEEQQRKEREEEEQ 124
E+E + E + EQ+ E K+++EE +++++ QE++ K +E++ +E+EE+ +
Sbjct: 435 EKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIR 494
Query: 125 KRQEKKEKEEAL---QKMLDQAENELENGTTWQNPE 157
+++EK ++E Q+ + + E E W+ E
Sbjct: 495 EQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEE 530
Score = 57.0 bits (136), Expect = 4e-08
Identities = 34/128 (26%), Positives = 77/128 (60%), Gaps = 15/128 (11%)
Query: 45 KEEEEDTFIEEQQLEE--EKLLERERQRLHEEWLLREQ--KAQEEFRIKKEKEEAAKKRQ 100
+++EE + +E++++E EK+ E+E + +E +REQ K + + + EKEE ++++
Sbjct: 357 QQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQE 416
Query: 101 E---EQERKLKEQ----WEEQQR----KEREEEEQKRQEKKEKEEALQKMLDQAENELEN 149
E E+E K++ Q WE++++ +E+ E++K +E++EK + +K+ +Q + + +
Sbjct: 417 EMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQE 476
Query: 150 GTTWQNPE 157
W+ E
Sbjct: 477 AKMWRQEE 484
Score = 56.6 bits (135), Expect = 5e-08
Identities = 39/155 (25%), Positives = 89/155 (57%), Gaps = 14/155 (9%)
Query: 5 EKMTFPEKPSHKKYRAALKKEKRKKRRQELARLRDSGLSQKE---EEEDTFIEEQQL--E 59
EKM E+ H++ + +++E++++ ++E+ R + Q+E ++E +E+++ +
Sbjct: 498 EKMWRQEEKIHEQEK--IREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQ 555
Query: 60 EEKLLERERQRLHEEWLLREQ-----KAQEEFRIKKEKEEAAKKRQEEQERKLKEQWEEQ 114
EEK+ +E + +E +REQ + +E+ R ++EK +++ EQE +EQ E+
Sbjct: 556 EEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKM 615
Query: 115 QRKERE--EEEQKRQEKKEKEEALQKMLDQAENEL 147
+E + E+E+K QE++EK ++ + + E ++
Sbjct: 616 GEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKI 650
Score = 54.3 bits (129), Expect = 2e-07
Identities = 35/124 (28%), Positives = 75/124 (60%), Gaps = 6/124 (4%)
Query: 23 KKEKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQLEEEKLLERERQRLHEEWLL--REQ 80
++E++ + +E + ++ + ++EE+ E+ + +EE + E+E + +E ++ +E+
Sbjct: 365 RQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEE 424
Query: 81 KAQEEFRIKKEKEEAAKKRQEEQERKLKEQWEEQQRKEREEEEQKRQEKKEKEEALQKML 140
K + + + EKEE K R+ E++ +E+ EQ+ K +EEE+ + QEK++++EA KM
Sbjct: 425 KMRRQEEMMWEKEE--KIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEA--KMW 480
Query: 141 DQAE 144
Q E
Sbjct: 481 RQEE 484
Score = 52.4 bits (124), Expect = 9e-07
Identities = 30/112 (26%), Positives = 65/112 (58%), Gaps = 9/112 (8%)
Query: 42 LSQKEEEEDTFIEEQQLEEEKLLERERQRLHEEWLLREQKAQEEFRIKKEKEEAAKKRQE 101
L+Q++EE+ EE+ E E+ ++ + +++ E+ E+K +E+ + +EE +++E
Sbjct: 355 LNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQ----EEKIREQEEKMRRQEEMMWEKEE 410
Query: 102 EQERKLKEQWEEQQRKEREEE-----EQKRQEKKEKEEALQKMLDQAENELE 148
+ R+ + WE++++ R+EE E+K +E +EK +K+ +Q E E
Sbjct: 411 KMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQE 462
Score = 52.0 bits (123), Expect = 1e-06
Identities = 30/108 (27%), Positives = 62/108 (57%), Gaps = 6/108 (5%)
Query: 42 LSQKEEEEDTFIEEQQLEEEKLLERERQRLHEEWLLREQKAQEEFRIKKEKEEAAKKRQE 101
L + EE + + Q +EEK+ +E + +EW E+K QE+ +E+EE ++++E
Sbjct: 342 LQAQVEENELWNRLNQQQEEKMWRQEEK--IQEW---EEKIQEQEEKIREQEEKIREQEE 396
Query: 102 EQERKLKEQWEEQQRKEREEEEQ-KRQEKKEKEEALQKMLDQAENELE 148
+ R+ + WE++++ R+EE +++EK ++E + ++ ELE
Sbjct: 397 KMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELE 444
Score = 48.5 bits (114), Expect = 1e-05
Identities = 39/131 (29%), Positives = 71/131 (54%), Gaps = 12/131 (9%)
Query: 22 LKKEKRKKRRQELARLRDSGLSQ-----KEEEEDTFIEEQQLEEEKLLERERQRLHEEWL 76
+K+ KRK R +L + ++ KE + + + Q+EE +L R Q+ E+
Sbjct: 305 VKELKRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMW 364
Query: 77 LREQKAQEEFRIKKEKEEAAKKRQEEQERKLKEQWEEQQRKER---EEEEQKRQEKKEKE 133
+E+K QE +EK + +++ EQE K++EQ E+ +R+E E+EE+ R++++
Sbjct: 365 RQEEKIQEW----EEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMW 420
Query: 134 EALQKMLDQAE 144
E +KM Q E
Sbjct: 421 EKEEKMRRQEE 431
Score = 44.3 bits (103), Expect = 2e-04
Identities = 38/138 (27%), Positives = 72/138 (52%), Gaps = 11/138 (7%)
Query: 26 KRKKRRQELARLRDSGLSQKEEEEDTFIEEQQLEEEKLLERERQRLHEEWLLREQKAQEE 85
K KR+ E A+L Q + E D +E Q KL + + +E W Q+ +E+
Sbjct: 306 KELKRKLERAKLL-LPQQQLQAEADHLGKELQSVSAKLQAQVEE--NELWNRLNQQQEEK 362
Query: 86 FRIKKEKEEAAKKRQEEQERKLKEQWEEQQRKEREE----EEQKRQEKKEKEEALQKMLD 141
++EK + +++ +EQE K++EQ E++ +E+EE +E+ EK+EK ++M+
Sbjct: 363 MWRQEEKIQEWEEKIQEQEEKIREQ--EEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMW 420
Query: 142 QAENEL--ENGTTWQNPE 157
+ E ++ + W+ E
Sbjct: 421 EKEEKMRRQEEMMWEKEE 438
Score = 40.4 bits (93), Expect = 0.004
Identities = 28/112 (25%), Positives = 58/112 (51%), Gaps = 15/112 (13%)
Query: 1 MAAPEKMTFPEKPSHKKYRAALKKEKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQLEE 60
M E+ ++ ++ ++++++K R QE +K E++ ++EQ E
Sbjct: 622 MCEQEEKMQEQEEKMRRQEEKIREQEKKIREQE----------EKIREQEEMMQEQ---E 668
Query: 61 EKLLERERQRLHEEWLLREQKAQEEFRIKKEKEEAAKKRQEEQERKLKEQWE 112
EK+ E+E + +E ++EQ +E+ R ++EK + R +QE K++E E
Sbjct: 669 EKMWEQEEKMCEQEEKMQEQ--EEKMRRQEEKMWEQEVRLRQQEEKMQEHQE 718
Score = 37.7 bits (86), Expect = 0.023
Identities = 34/128 (26%), Positives = 69/128 (53%), Gaps = 10/128 (7%)
Query: 18 YRAALKKEKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQLEEEKLLERERQRLHEEWLL 77
YR + E+ K++ A+L++ Q E E + I+ E ++ LER + L ++ L
Sbjct: 271 YRNTITDEELKEKN---AKLQEK--LQLVESEKSEIQLNVKELKRKLERAKLLLPQQQL- 324
Query: 78 REQKAQEEFRIKKEKEEAAKKRQEEQERKLKEQWEEQQRKEREEEEQKRQEKKEK-EEAL 136
+A+ + K+ + +AK + + +E +L + +QQ ++ +E+K QE +EK +E
Sbjct: 325 ---QAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQE 381
Query: 137 QKMLDQAE 144
+K+ +Q E
Sbjct: 382 EKIREQEE 389
>gi|116089325 splicing factor, arginine/serine-rich 12 isoform a
[Homo sapiens]
Length = 624
Score = 70.9 bits (172), Expect = 2e-12
Identities = 63/255 (24%), Positives = 99/255 (38%), Gaps = 16/255 (6%)
Query: 228 SEEETYQQFLDFYEDVLPEFKNVGKVIQFKVSCNLEPHLRGNVYVQYQSEEECQAALSLF 287
S+ T Q L+F FK VG+V +F E +V++ + AL+ F
Sbjct: 191 SQTTTADQLLEF-------FKQVGEV-KFVRMAGDETQPTRFAFVEFADQNSVPRALA-F 241
Query: 288 NGRWYAGRQLQCEFCPVTRWKMAICGLFEIQQCPRGKHCNFLHVFRNPNNEFWEANRDIY 347
NG + R L+ + AI E+ P+ V + + I
Sbjct: 242 NGVMFGDRPLK-----INHSNNAIVKPPEMT--PQAAAKELEEVMKRVREAQSFISAAIE 294
Query: 348 LSPDRTGSSFGKNSERRERMGHHDDYYSRLRGRRNPSPDHSYKRNGESERKSSRHRGKKS 407
++ G S R S R +R+ S S N R+ R R K
Sbjct: 295 PESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSP 354
Query: 408 HKRTSKSRERHNSRSRGRNRDRSRDRSRGRGSRSRSRSRSRRSRRSRSQSSSRSRSRGRR 467
HK+ SKSRER SRSR +RD+ +D + R + + R R R + + + RG+
Sbjct: 355 HKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKN 414
Query: 468 RSGNRDRTVQSPKSK 482
+ +++R K K
Sbjct: 415 KDRDKEREKDREKDK 429
Score = 60.5 bits (145), Expect = 3e-09
Identities = 40/159 (25%), Positives = 84/159 (52%), Gaps = 9/159 (5%)
Query: 14 SHKKYRAALKKEKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQLEEEKLLERERQRLHE 73
S +K R K +K+ + R S +++ +DT E+ E+E++ E++R++ E
Sbjct: 343 SRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDT--REKIKEKERVKEKDREKERE 400
Query: 74 EWLLREQKAQEEFRIKKEKEEAAKKRQEEQERKLKEQWEEQQRKEREEEEQKRQEK-KEK 132
RE K +E + K +E K R++++E+ + + E++ K+R++E++K Q+K KE+
Sbjct: 401 REKERE-KEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKER 459
Query: 133 EEALQKMLDQAENELENGTTWQNPEPPVDFRVMEKDRAN 171
E+ K +D+ + + T PP + + R++
Sbjct: 460 EKDRSKEIDEKRKKDKKSRT-----PPRSYNASRRSRSS 493
Score = 57.0 bits (136), Expect = 4e-08
Identities = 41/131 (31%), Positives = 59/131 (45%), Gaps = 10/131 (7%)
Query: 359 KNSERRERMGHHDDYYSRLRGRRNPSPDHSYKRNGESERKSSRHRGKKSHKRTSKSRERH 418
+ + +ER + D R + R D R E E++ + R K+ K K +ER
Sbjct: 404 EREKEKERGKNKDRDKEREKDREK---DKEKDREREREKEHEKDRDKEKEKEQDKEKERE 460
Query: 419 NSRSRGRNRDRSRD-------RSRGRGSRSRSRSRSRRSRRSRSQSSSRSRSRGRRRSGN 471
RS+ + R +D RS RSRS SR RR RRSRS S S S+ +R +
Sbjct: 461 KDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSS 520
Query: 472 RDRTVQSPKSK 482
R + +S K
Sbjct: 521 RSPSPRSRNKK 531
Score = 54.3 bits (129), Expect = 2e-07
Identities = 36/158 (22%), Positives = 77/158 (48%), Gaps = 6/158 (3%)
Query: 14 SHKKYRAALKKEKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQLEEEKLLERERQRLHE 73
+ K R++ K R+KR Q R R S+ +++ + + K ER + R
Sbjct: 312 TRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRS 371
Query: 74 EWLLREQKAQEEFRIKKEKEEAAKKRQEEQERKLKEQWEEQQRKEREEEEQKRQEK-KEK 132
+ + +E+ + K+ +E ++++ E+E++ +++ E + K+R++E +K +EK KEK
Sbjct: 372 HSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEK 431
Query: 133 EEALQKMLDQAENELENGTTWQNPEPPVDFRVMEKDRA 170
+ ++ E E E + + + EKDR+
Sbjct: 432 DRERER-----EKEHEKDRDKEKEKEQDKEKEREKDRS 464
Score = 45.8 bits (107), Expect = 9e-05
Identities = 29/128 (22%), Positives = 69/128 (53%), Gaps = 11/128 (8%)
Query: 5 EKMTFPEKPSHKKYRAALKKEKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQLEEEKLL 64
EK+ E+ K ++EK +++ +E + +D KE E+D ++ ++EK
Sbjct: 382 EKIKEKERVKEKDREKEREREKEREKEKERGKNKDR---DKEREKD-----REKDKEKDR 433
Query: 65 ERERQRLHEEWLLREQKAQEEFRIKKEKE---EAAKKRQEEQERKLKEQWEEQQRKEREE 121
ERER++ HE+ +E++ +++ ++EK+ E +KR+++++ + + R+ R
Sbjct: 434 EREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSS 493
Query: 122 EEQKRQEK 129
++R+ +
Sbjct: 494 SRERRRRR 501
Score = 44.3 bits (103), Expect = 2e-04
Identities = 41/129 (31%), Positives = 59/129 (45%), Gaps = 17/129 (13%)
Query: 358 GKNSER---RERMGHHDDYYSRLRGRRNPSPDHSYKRNGESERKSSRHRGKKS------- 407
GKN +R RE+ D R R R +H R+ E E++ + + ++
Sbjct: 412 GKNKDRDKEREKDREKDKEKDREREREK---EHEKDRDKEKEKEQDKEKEREKDRSKEID 468
Query: 408 --HKRTSKSRERHNSRSRGRNRDRSRDRSRGRGSRSRSRSRSRRSRRSRSQSSSRSRSRG 465
K+ KSR S + R R RS R R R RSRS SRS R+ ++ + SSRS S
Sbjct: 469 EKRKKDKKSRTPPRSYNASR-RSRSSSRERRR-RRSRSSSRSPRTSKTIKRKSSRSPSPR 526
Query: 466 RRRSGNRDR 474
R ++ R
Sbjct: 527 SRNKKDKKR 535
Score = 42.7 bits (99), Expect = 7e-04
Identities = 34/173 (19%), Positives = 75/173 (43%), Gaps = 18/173 (10%)
Query: 11 EKPSHKKYRAALKKEKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQLEEEKLL------ 64
EK K +KE K R +E + +D ++E++ I+E++ +++K
Sbjct: 426 EKDKEKDREREREKEHEKDRDKEKEKEQDKE-KEREKDRSKEIDEKRKKDKKSRTPPRSY 484
Query: 65 ---------ERERQRLHEEWLLREQKAQEEFRIKKEKEEAAKKRQEEQERKLKEQWEEQQ 115
RER+R R + + + K + + + R ++ +++ KE+ +
Sbjct: 485 NASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISE 544
Query: 116 RKEREEEEQKRQEKKEKEEALQKMLDQAENELENGTTWQNPEPPVDFRVMEKD 168
R+ERE R+ +++ ++ L++ L+ + P+ V V +KD
Sbjct: 545 RRERERSTSMRKSSNDRDG--KEKLEKNSTSLKEKEHNKEPDSSVSKEVDDKD 595
Score = 42.4 bits (98), Expect = 0.001
Identities = 34/128 (26%), Positives = 52/128 (40%), Gaps = 6/128 (4%)
Query: 359 KNSERRERMGHHDDYYSRLRGRRNPSPDHSYKRNGESERKSSRHRGKKSHKRT--SKSRE 416
K+ ER H D ++ + R+ E + K + + ++ R+ + R
Sbjct: 431 KDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRS 490
Query: 417 RHNSRSRGRNRDRSRDRSRGRG---SRSRSRSRSRRSRRSRSQSSSRSRSRGRRRSGNRD 473
R +SR R R R RS RS R SRS S RSR + + + R R R+
Sbjct: 491 RSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERR-ERE 549
Query: 474 RTVQSPKS 481
R+ KS
Sbjct: 550 RSTSMRKS 557
Score = 41.2 bits (95), Expect = 0.002
Identities = 32/117 (27%), Positives = 48/117 (41%), Gaps = 13/117 (11%)
Query: 359 KNSERRERMGHHDDYYSRLRGRRNPSPDHSYK-----RNGESERKSSRHRGKKSHKRTSK 413
K ER + D R + +++ +P SY R+ ER+ R R RTSK
Sbjct: 455 KEKEREKDRSKEIDE-KRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSK 513
Query: 414 SRERHNSRSRGRNRDRSRDRSRGRGSRSRSRSRSRRSRRSRSQSSSRSRSRGRRRSG 470
+ +R +SRS RSR + + R + R S R + S+ R R G
Sbjct: 514 TIKRKSSRSPS-------PRSRNKKDKKREKERDHISERRERERSTSMRKSSNDRDG 563
Score = 40.4 bits (93), Expect = 0.004
Identities = 29/166 (17%), Positives = 71/166 (42%), Gaps = 1/166 (0%)
Query: 5 EKMTFPEKPSHKKYRAALKKEKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQLEEEKLL 64
EK EK K+ K++ K+R ++ + ++ ++ E+E +++ E+E+
Sbjct: 396 EKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDK 455
Query: 65 ERERQRLHEEWLLREQKAQEEFRIKKEKEEAAKKRQEEQERKLKEQWEEQQRKEREEEEQ 124
E+ER++ + + ++K ++ R A+++ + + + + R R +
Sbjct: 456 EKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTI 515
Query: 125 KRQEKKEKEEALQKMLD-QAENELENGTTWQNPEPPVDFRVMEKDR 169
KR+ + + D + E E ++ + + E R DR
Sbjct: 516 KRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKSSNDR 561
Score = 37.7 bits (86), Expect = 0.023
Identities = 27/100 (27%), Positives = 43/100 (43%), Gaps = 7/100 (7%)
Query: 381 RNPSPDHSYKRNGESERKSSRHRGKKSHKRTSKSRERHNSRSRGRNRDRS----RDRSRG 436
R+ D K++ +S + + + +S+ R R SRS R+ S R SR
Sbjct: 463 RSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRS 522
Query: 437 RGSRSRSRSRSRRSRRSRSQSSSRSRSRG---RRRSGNRD 473
RSR++ +R + S R R R R+ S +RD
Sbjct: 523 PSPRSRNKKDKKREKERDHISERRERERSTSMRKSSNDRD 562
Score = 35.8 bits (81), Expect = 0.089
Identities = 30/152 (19%), Positives = 65/152 (42%), Gaps = 17/152 (11%)
Query: 8 TFPEKPSHKKYRAALKKEKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQLEEEKLLERE 67
T P + + + +E+R++R + +R + + K + + + +++K E+E
Sbjct: 479 TPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKE 538
Query: 68 RQRLHEEWLLREQKAQEEFRIKKEKEEAAKKRQEEQERKLKEQWEEQQRKEREEEEQKRQ 127
R + E ++E+E + R+ +R KE+ E+ +E+E K
Sbjct: 539 RDHISE---------------RRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEP 583
Query: 128 EKKEKEEALQKMLDQA-ENELE-NGTTWQNPE 157
+ +E K + EN+++ NG N E
Sbjct: 584 DSSVSKEVDDKDAPRTEENKIQHNGNCQLNEE 615
>gi|21040255 splicing factor, arginine/serine-rich 12 isoform b
[Homo sapiens]
Length = 508
Score = 70.9 bits (172), Expect = 2e-12
Identities = 63/255 (24%), Positives = 99/255 (38%), Gaps = 16/255 (6%)
Query: 228 SEEETYQQFLDFYEDVLPEFKNVGKVIQFKVSCNLEPHLRGNVYVQYQSEEECQAALSLF 287
S+ T Q L+F FK VG+V +F E +V++ + AL+ F
Sbjct: 75 SQTTTADQLLEF-------FKQVGEV-KFVRMAGDETQPTRFAFVEFADQNSVPRALA-F 125
Query: 288 NGRWYAGRQLQCEFCPVTRWKMAICGLFEIQQCPRGKHCNFLHVFRNPNNEFWEANRDIY 347
NG + R L+ + AI E+ P+ V + + I
Sbjct: 126 NGVMFGDRPLK-----INHSNNAIVKPPEMT--PQAAAKELEEVMKRVREAQSFISAAIE 178
Query: 348 LSPDRTGSSFGKNSERRERMGHHDDYYSRLRGRRNPSPDHSYKRNGESERKSSRHRGKKS 407
++ G S R S R +R+ S S N R+ R R K
Sbjct: 179 PESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSP 238
Query: 408 HKRTSKSRERHNSRSRGRNRDRSRDRSRGRGSRSRSRSRSRRSRRSRSQSSSRSRSRGRR 467
HK+ SKSRER SRSR +RD+ +D + R + + R R R + + + RG+
Sbjct: 239 HKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKN 298
Query: 468 RSGNRDRTVQSPKSK 482
+ +++R K K
Sbjct: 299 KDRDKEREKDREKDK 313
Score = 60.5 bits (145), Expect = 3e-09
Identities = 40/159 (25%), Positives = 84/159 (52%), Gaps = 9/159 (5%)
Query: 14 SHKKYRAALKKEKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQLEEEKLLERERQRLHE 73
S +K R K +K+ + R S +++ +DT E+ E+E++ E++R++ E
Sbjct: 227 SRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDT--REKIKEKERVKEKDREKERE 284
Query: 74 EWLLREQKAQEEFRIKKEKEEAAKKRQEEQERKLKEQWEEQQRKEREEEEQKRQEK-KEK 132
RE K +E + K +E K R++++E+ + + E++ K+R++E++K Q+K KE+
Sbjct: 285 REKERE-KEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKER 343
Query: 133 EEALQKMLDQAENELENGTTWQNPEPPVDFRVMEKDRAN 171
E+ K +D+ + + T PP + + R++
Sbjct: 344 EKDRSKEIDEKRKKDKKSRT-----PPRSYNASRRSRSS 377
Score = 57.0 bits (136), Expect = 4e-08
Identities = 41/131 (31%), Positives = 59/131 (45%), Gaps = 10/131 (7%)
Query: 359 KNSERRERMGHHDDYYSRLRGRRNPSPDHSYKRNGESERKSSRHRGKKSHKRTSKSRERH 418
+ + +ER + D R + R D R E E++ + R K+ K K +ER
Sbjct: 288 EREKEKERGKNKDRDKEREKDREK---DKEKDREREREKEHEKDRDKEKEKEQDKEKERE 344
Query: 419 NSRSRGRNRDRSRD-------RSRGRGSRSRSRSRSRRSRRSRSQSSSRSRSRGRRRSGN 471
RS+ + R +D RS RSRS SR RR RRSRS S S S+ +R +
Sbjct: 345 KDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSS 404
Query: 472 RDRTVQSPKSK 482
R + +S K
Sbjct: 405 RSPSPRSRNKK 415
Score = 54.3 bits (129), Expect = 2e-07
Identities = 36/158 (22%), Positives = 77/158 (48%), Gaps = 6/158 (3%)
Query: 14 SHKKYRAALKKEKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQLEEEKLLERERQRLHE 73
+ K R++ K R+KR Q R R S+ +++ + + K ER + R
Sbjct: 196 TRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRS 255
Query: 74 EWLLREQKAQEEFRIKKEKEEAAKKRQEEQERKLKEQWEEQQRKEREEEEQKRQEK-KEK 132
+ + +E+ + K+ +E ++++ E+E++ +++ E + K+R++E +K +EK KEK
Sbjct: 256 HSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEK 315
Query: 133 EEALQKMLDQAENELENGTTWQNPEPPVDFRVMEKDRA 170
+ ++ E E E + + + EKDR+
Sbjct: 316 DRERER-----EKEHEKDRDKEKEKEQDKEKEREKDRS 348
Score = 45.8 bits (107), Expect = 9e-05
Identities = 29/128 (22%), Positives = 69/128 (53%), Gaps = 11/128 (8%)
Query: 5 EKMTFPEKPSHKKYRAALKKEKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQLEEEKLL 64
EK+ E+ K ++EK +++ +E + +D KE E+D ++ ++EK
Sbjct: 266 EKIKEKERVKEKDREKEREREKEREKEKERGKNKDR---DKEREKD-----REKDKEKDR 317
Query: 65 ERERQRLHEEWLLREQKAQEEFRIKKEKE---EAAKKRQEEQERKLKEQWEEQQRKEREE 121
ERER++ HE+ +E++ +++ ++EK+ E +KR+++++ + + R+ R
Sbjct: 318 EREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSS 377
Query: 122 EEQKRQEK 129
++R+ +
Sbjct: 378 SRERRRRR 385
Score = 44.3 bits (103), Expect = 2e-04
Identities = 41/129 (31%), Positives = 59/129 (45%), Gaps = 17/129 (13%)
Query: 358 GKNSER---RERMGHHDDYYSRLRGRRNPSPDHSYKRNGESERKSSRHRGKKS------- 407
GKN +R RE+ D R R R +H R+ E E++ + + ++
Sbjct: 296 GKNKDRDKEREKDREKDKEKDREREREK---EHEKDRDKEKEKEQDKEKEREKDRSKEID 352
Query: 408 --HKRTSKSRERHNSRSRGRNRDRSRDRSRGRGSRSRSRSRSRRSRRSRSQSSSRSRSRG 465
K+ KSR S + R R RS R R R RSRS SRS R+ ++ + SSRS S
Sbjct: 353 EKRKKDKKSRTPPRSYNASR-RSRSSSRERRR-RRSRSSSRSPRTSKTIKRKSSRSPSPR 410
Query: 466 RRRSGNRDR 474
R ++ R
Sbjct: 411 SRNKKDKKR 419
Score = 42.7 bits (99), Expect = 7e-04
Identities = 34/173 (19%), Positives = 75/173 (43%), Gaps = 18/173 (10%)
Query: 11 EKPSHKKYRAALKKEKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQLEEEKLL------ 64
EK K +KE K R +E + +D ++E++ I+E++ +++K
Sbjct: 310 EKDKEKDREREREKEHEKDRDKEKEKEQDKE-KEREKDRSKEIDEKRKKDKKSRTPPRSY 368
Query: 65 ---------ERERQRLHEEWLLREQKAQEEFRIKKEKEEAAKKRQEEQERKLKEQWEEQQ 115
RER+R R + + + K + + + R ++ +++ KE+ +
Sbjct: 369 NASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISE 428
Query: 116 RKEREEEEQKRQEKKEKEEALQKMLDQAENELENGTTWQNPEPPVDFRVMEKD 168
R+ERE R+ +++ ++ L++ L+ + P+ V V +KD
Sbjct: 429 RRERERSTSMRKSSNDRDG--KEKLEKNSTSLKEKEHNKEPDSSVSKEVDDKD 479
Score = 42.4 bits (98), Expect = 0.001
Identities = 34/128 (26%), Positives = 52/128 (40%), Gaps = 6/128 (4%)
Query: 359 KNSERRERMGHHDDYYSRLRGRRNPSPDHSYKRNGESERKSSRHRGKKSHKRT--SKSRE 416
K+ ER H D ++ + R+ E + K + + ++ R+ + R
Sbjct: 315 KDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRS 374
Query: 417 RHNSRSRGRNRDRSRDRSRGRG---SRSRSRSRSRRSRRSRSQSSSRSRSRGRRRSGNRD 473
R +SR R R R RS RS R SRS S RSR + + + R R R+
Sbjct: 375 RSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERR-ERE 433
Query: 474 RTVQSPKS 481
R+ KS
Sbjct: 434 RSTSMRKS 441
Score = 41.2 bits (95), Expect = 0.002
Identities = 32/117 (27%), Positives = 48/117 (41%), Gaps = 13/117 (11%)
Query: 359 KNSERRERMGHHDDYYSRLRGRRNPSPDHSYK-----RNGESERKSSRHRGKKSHKRTSK 413
K ER + D R + +++ +P SY R+ ER+ R R RTSK
Sbjct: 339 KEKEREKDRSKEIDE-KRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSK 397
Query: 414 SRERHNSRSRGRNRDRSRDRSRGRGSRSRSRSRSRRSRRSRSQSSSRSRSRGRRRSG 470
+ +R +SRS RSR + + R + R S R + S+ R R G
Sbjct: 398 TIKRKSSRSPS-------PRSRNKKDKKREKERDHISERRERERSTSMRKSSNDRDG 447
Score = 40.4 bits (93), Expect = 0.004
Identities = 29/166 (17%), Positives = 71/166 (42%), Gaps = 1/166 (0%)
Query: 5 EKMTFPEKPSHKKYRAALKKEKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQLEEEKLL 64
EK EK K+ K++ K+R ++ + ++ ++ E+E +++ E+E+
Sbjct: 280 EKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDK 339
Query: 65 ERERQRLHEEWLLREQKAQEEFRIKKEKEEAAKKRQEEQERKLKEQWEEQQRKEREEEEQ 124
E+ER++ + + ++K ++ R A+++ + + + + R R +
Sbjct: 340 EKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTI 399
Query: 125 KRQEKKEKEEALQKMLD-QAENELENGTTWQNPEPPVDFRVMEKDR 169
KR+ + + D + E E ++ + + E R DR
Sbjct: 400 KRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKSSNDR 445
Score = 37.7 bits (86), Expect = 0.023
Identities = 27/100 (27%), Positives = 43/100 (43%), Gaps = 7/100 (7%)
Query: 381 RNPSPDHSYKRNGESERKSSRHRGKKSHKRTSKSRERHNSRSRGRNRDRS----RDRSRG 436
R+ D K++ +S + + + +S+ R R SRS R+ S R SR
Sbjct: 347 RSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRS 406
Query: 437 RGSRSRSRSRSRRSRRSRSQSSSRSRSRG---RRRSGNRD 473
RSR++ +R + S R R R R+ S +RD
Sbjct: 407 PSPRSRNKKDKKREKERDHISERRERERSTSMRKSSNDRD 446
Score = 35.8 bits (81), Expect = 0.089
Identities = 30/152 (19%), Positives = 65/152 (42%), Gaps = 17/152 (11%)
Query: 8 TFPEKPSHKKYRAALKKEKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQLEEEKLLERE 67
T P + + + +E+R++R + +R + + K + + + +++K E+E
Sbjct: 363 TPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKE 422
Query: 68 RQRLHEEWLLREQKAQEEFRIKKEKEEAAKKRQEEQERKLKEQWEEQQRKEREEEEQKRQ 127
R + E ++E+E + R+ +R KE+ E+ +E+E K
Sbjct: 423 RDHISE---------------RRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEP 467
Query: 128 EKKEKEEALQKMLDQA-ENELE-NGTTWQNPE 157
+ +E K + EN+++ NG N E
Sbjct: 468 DSSVSKEVDDKDAPRTEENKIQHNGNCQLNEE 499
>gi|102467235 inner centromere protein antigens 135/155kDa isoform 1
[Homo sapiens]
Length = 918
Score = 70.9 bits (172), Expect = 2e-12
Identities = 45/138 (32%), Positives = 84/138 (60%), Gaps = 11/138 (7%)
Query: 17 KYRAALKK----EKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQLEEEKLLER--ERQR 70
K +AA KK E R+K+ +E RLR ++E +++++ EE++ L + E +R
Sbjct: 624 KKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKR 683
Query: 71 LHEEWLLREQKAQEEFRIKKEKEEAAKKRQEEQERKLKEQWEEQQRKEREEEEQKRQEKK 130
L E+ REQ+ +E+ R ++E+ E ++R+E++ R+ + Q EQ+R+ +E Q +E +
Sbjct: 684 LAEQ---REQERREQERREQERRE--QERREQERREQERQLAEQERRREQERLQAERELQ 738
Query: 131 EKEEALQKMLDQAENELE 148
E+E+AL+ +Q + ELE
Sbjct: 739 EREKALRLQKEQLQRELE 756
Score = 65.5 bits (158), Expect = 1e-10
Identities = 42/153 (27%), Positives = 81/153 (52%), Gaps = 4/153 (2%)
Query: 22 LKKEKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQLEEEKLLERERQRLHEEWLLREQK 81
+K+EK+K+ Q+ A++ + KEE +++ +K+ E E +R EE R +
Sbjct: 591 MKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRW 650
Query: 82 AQEEFRIKKEKEEAAKKRQEEQERKLK----EQWEEQQRKEREEEEQKRQEKKEKEEALQ 137
Q+E ++ +E KK++EEQER K ++ EQ+ +ER E+E++ QE++E+E Q
Sbjct: 651 LQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQ 710
Query: 138 KMLDQAENELENGTTWQNPEPPVDFRVMEKDRA 170
+ +Q E + + + E+++A
Sbjct: 711 ERREQERQLAEQERRREQERLQAERELQEREKA 743
Score = 62.4 bits (150), Expect = 9e-10
Identities = 37/122 (30%), Positives = 75/122 (61%), Gaps = 8/122 (6%)
Query: 23 KKEKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQLEEEKLLERERQRLHE------EWL 76
K E+ K+RR E +L+ +K + +E+ + E++K +E++ ++ E E
Sbjct: 558 KVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEER 617
Query: 77 LREQKAQEEFRIKKEKEEAAKKRQEEQERKLKEQWEEQQRKEREEEEQKRQEKKEKEEAL 136
L E+KA+++ KK +E A+++QEE+ R+L+ W +Q+ +ER +E +++K+E++E L
Sbjct: 618 LAEEKAKKKAAAKKMEEVEARRKQEEEARRLR--WLQQEEEERRHQELLQKKKEEEQERL 675
Query: 137 QK 138
+K
Sbjct: 676 RK 677
Score = 58.5 bits (140), Expect = 1e-08
Identities = 42/134 (31%), Positives = 78/134 (58%), Gaps = 14/134 (10%)
Query: 22 LKKEKRKKRRQELARLRDSGLSQKEEEEDTF---IEEQQLEEEKLLERERQRLHEEWLLR 78
L++E+ ++R QEL + +KEEE++ E ++L E++ ER Q E+ R
Sbjct: 651 LQQEEEERRHQELLQ------KKKEEEQERLRKAAEAKRLAEQREQERREQERREQER-R 703
Query: 79 EQKAQEEFRIKKEKEEAAKKRQEEQERKLKE----QWEEQQRKEREEEEQKRQEKKEKEE 134
EQ+ +E+ R ++E++ A ++R+ EQER E + E+ R ++E+ +++ +EKK+KEE
Sbjct: 704 EQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEE 763
Query: 135 ALQKMLDQAENELE 148
+ Q + E E
Sbjct: 764 QQRLAERQLQEEQE 777
Score = 57.8 bits (138), Expect = 2e-08
Identities = 42/130 (32%), Positives = 79/130 (60%), Gaps = 6/130 (4%)
Query: 11 EKPSHKKYRAALKKEKRKKRRQ--ELARLRDSGLSQKEEEEDTFIE--EQQLEEEKLLER 66
E+ H++ K+E++++ R+ E RL + ++ E+E E EQ+ E++ E+
Sbjct: 656 EERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQ 715
Query: 67 ERQRLHEEWLLREQKAQEEFRIKKEKEEAAKKRQEEQERKLKE-QWEEQQRKEREEEEQK 125
ERQ L E+ REQ+ + R +E+E+A + ++E+ +R+L+E + +E+Q++ E + Q+
Sbjct: 716 ERQ-LAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQE 774
Query: 126 RQEKKEKEEA 135
QEKK KE A
Sbjct: 775 EQEKKAKEAA 784
Score = 54.7 bits (130), Expect = 2e-07
Identities = 35/123 (28%), Positives = 76/123 (61%), Gaps = 9/123 (7%)
Query: 27 RKKRRQELARLRDSGLSQK--EEEEDTFIEEQQLEEEKLLERERQRLHEEWLLREQKAQE 84
+KK+ +E RLR + +++ E+ E E+++ E+E+ RE++R +E +E++ E
Sbjct: 665 QKKKEEEQERLRKAAEAKRLAEQREQERREQERREQER---REQERREQERREQERQLAE 721
Query: 85 EFRIKKEKEEAAKKRQEEQERKLKEQWEEQQR----KEREEEEQKRQEKKEKEEALQKML 140
+ R ++++ A++ +E+E+ L+ Q E+ QR K+++EE+Q+ E++ +EE +K
Sbjct: 722 QERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAK 781
Query: 141 DQA 143
+ A
Sbjct: 782 EAA 784
Score = 50.8 bits (120), Expect = 3e-06
Identities = 32/117 (27%), Positives = 67/117 (57%), Gaps = 16/117 (13%)
Query: 28 KKRRQELARLRDSGLSQKEEEEDTFIEEQQLEEEKLLERERQRLHEEWLLREQKAQEEFR 87
+K RQ L LR +KEE E QL +K+ E +R+RL E L RE++ ++ +
Sbjct: 536 EKERQRLENLR-----RKEEAE-------QLRRQKVEEDKRRRLEEVKLKREERLRKVLQ 583
Query: 88 IKKEKEEAAKKRQEEQERKLKEQWEEQQRKEREEEEQKRQEKKEKEEALQKMLDQAE 144
+ E ++ +EE+++++++++ + K + +E++ E+K K++A K +++ E
Sbjct: 584 AR----ERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVE 636
Score = 50.8 bits (120), Expect = 3e-06
Identities = 35/119 (29%), Positives = 70/119 (58%), Gaps = 11/119 (9%)
Query: 25 EKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQLEEEKLLERERQRLHEEWLLREQKAQE 84
E+R++ R+E R Q+ E++ +E+QL E++ RE++RL E L+E+ ++
Sbjct: 686 EQREQERREQERREQERREQERREQERREQERQLAEQER-RREQERLQAERELQER--EK 742
Query: 85 EFRIKKEK--EEAAKKRQEEQERKLKEQWEEQQRKEREEEEQKRQEKKEKEEALQKMLD 141
R++KE+ E +K+++E++++L E R+ +EE+E+K +E +AL +D
Sbjct: 743 ALRLQKEQLQRELEEKKKKEEQQRLAE------RQLQEEQEKKAKEAAGASKALNVTVD 795
Score = 43.1 bits (100), Expect = 6e-04
Identities = 29/85 (34%), Positives = 50/85 (58%), Gaps = 8/85 (9%)
Query: 64 LERERQRLHEEWLLREQKAQEEFRIKKEKEEAAKKRQEEQERKLKEQWEEQQRKEREEEE 123
+E+ERQRL LR ++ E+ R +K +E+ KR+ +E KLK EE+ RK + E
Sbjct: 535 VEKERQRLEN---LRRKEEAEQLRRQKVEED---KRRRLEEVKLKR--EERLRKVLQARE 586
Query: 124 QKRQEKKEKEEALQKMLDQAENELE 148
+ Q K+EK++ +++ Q + + E
Sbjct: 587 RVEQMKEEKKKQIEQKFAQIDEKTE 611
Score = 35.4 bits (80), Expect = 0.12
Identities = 24/67 (35%), Positives = 33/67 (49%), Gaps = 2/67 (2%)
Query: 394 ESERKSSRHRGKKSH--KRTSKSRERHNSRSRGRNRDRSRDRSRGRGSRSRSRSRSRRSR 451
E+ER +R K+ +T + R R +D +RD R R SR +SRS SR
Sbjct: 40 EAERMFTREFSKEPELMPKTPSQKNRRKKRRISYVQDENRDPIRRRLSRRKSRSSQLSSR 99
Query: 452 RSRSQSS 458
R RS+ S
Sbjct: 100 RLRSKDS 106
Score = 30.4 bits (67), Expect = 3.7
Identities = 16/90 (17%), Positives = 41/90 (45%), Gaps = 1/90 (1%)
Query: 394 ESERKSSRHRGKKSHKRTSKSRERHNSRSRGRNRDRSRDRSRGRGSRS-RSRSRSRRSRR 452
E ER+ R ++ ++ + +ER + ++R R++ R + R + R ++ R ++
Sbjct: 689 EQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQK 748
Query: 453 SRSQSSSRSRSRGRRRSGNRDRTVQSPKSK 482
+ Q + + + +R +Q + K
Sbjct: 749 EQLQRELEEKKKKEEQQRLAERQLQEEQEK 778
>gi|102467242 inner centromere protein antigens 135/155kDa isoform 2
[Homo sapiens]
Length = 914
Score = 70.9 bits (172), Expect = 2e-12
Identities = 45/138 (32%), Positives = 84/138 (60%), Gaps = 11/138 (7%)
Query: 17 KYRAALKK----EKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQLEEEKLLER--ERQR 70
K +AA KK E R+K+ +E RLR ++E +++++ EE++ L + E +R
Sbjct: 620 KKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKR 679
Query: 71 LHEEWLLREQKAQEEFRIKKEKEEAAKKRQEEQERKLKEQWEEQQRKEREEEEQKRQEKK 130
L E+ REQ+ +E+ R ++E+ E ++R+E++ R+ + Q EQ+R+ +E Q +E +
Sbjct: 680 LAEQ---REQERREQERREQERRE--QERREQERREQERQLAEQERRREQERLQAERELQ 734
Query: 131 EKEEALQKMLDQAENELE 148
E+E+AL+ +Q + ELE
Sbjct: 735 EREKALRLQKEQLQRELE 752
Score = 65.5 bits (158), Expect = 1e-10
Identities = 42/153 (27%), Positives = 81/153 (52%), Gaps = 4/153 (2%)
Query: 22 LKKEKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQLEEEKLLERERQRLHEEWLLREQK 81
+K+EK+K+ Q+ A++ + KEE +++ +K+ E E +R EE R +
Sbjct: 587 MKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRW 646
Query: 82 AQEEFRIKKEKEEAAKKRQEEQERKLK----EQWEEQQRKEREEEEQKRQEKKEKEEALQ 137
Q+E ++ +E KK++EEQER K ++ EQ+ +ER E+E++ QE++E+E Q
Sbjct: 647 LQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQ 706
Query: 138 KMLDQAENELENGTTWQNPEPPVDFRVMEKDRA 170
+ +Q E + + + E+++A
Sbjct: 707 ERREQERQLAEQERRREQERLQAERELQEREKA 739
Score = 62.4 bits (150), Expect = 9e-10
Identities = 37/122 (30%), Positives = 75/122 (61%), Gaps = 8/122 (6%)
Query: 23 KKEKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQLEEEKLLERERQRLHE------EWL 76
K E+ K+RR E +L+ +K + +E+ + E++K +E++ ++ E E
Sbjct: 554 KVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEER 613
Query: 77 LREQKAQEEFRIKKEKEEAAKKRQEEQERKLKEQWEEQQRKEREEEEQKRQEKKEKEEAL 136
L E+KA+++ KK +E A+++QEE+ R+L+ W +Q+ +ER +E +++K+E++E L
Sbjct: 614 LAEEKAKKKAAAKKMEEVEARRKQEEEARRLR--WLQQEEEERRHQELLQKKKEEEQERL 671
Query: 137 QK 138
+K
Sbjct: 672 RK 673
Score = 58.5 bits (140), Expect = 1e-08
Identities = 42/134 (31%), Positives = 78/134 (58%), Gaps = 14/134 (10%)
Query: 22 LKKEKRKKRRQELARLRDSGLSQKEEEEDTF---IEEQQLEEEKLLERERQRLHEEWLLR 78
L++E+ ++R QEL + +KEEE++ E ++L E++ ER Q E+ R
Sbjct: 647 LQQEEEERRHQELLQ------KKKEEEQERLRKAAEAKRLAEQREQERREQERREQER-R 699
Query: 79 EQKAQEEFRIKKEKEEAAKKRQEEQERKLKE----QWEEQQRKEREEEEQKRQEKKEKEE 134
EQ+ +E+ R ++E++ A ++R+ EQER E + E+ R ++E+ +++ +EKK+KEE
Sbjct: 700 EQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEE 759
Query: 135 ALQKMLDQAENELE 148
+ Q + E E
Sbjct: 760 QQRLAERQLQEEQE 773
Score = 57.8 bits (138), Expect = 2e-08
Identities = 42/130 (32%), Positives = 79/130 (60%), Gaps = 6/130 (4%)
Query: 11 EKPSHKKYRAALKKEKRKKRRQ--ELARLRDSGLSQKEEEEDTFIE--EQQLEEEKLLER 66
E+ H++ K+E++++ R+ E RL + ++ E+E E EQ+ E++ E+
Sbjct: 652 EERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQ 711
Query: 67 ERQRLHEEWLLREQKAQEEFRIKKEKEEAAKKRQEEQERKLKE-QWEEQQRKEREEEEQK 125
ERQ L E+ REQ+ + R +E+E+A + ++E+ +R+L+E + +E+Q++ E + Q+
Sbjct: 712 ERQ-LAEQERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQE 770
Query: 126 RQEKKEKEEA 135
QEKK KE A
Sbjct: 771 EQEKKAKEAA 780
Score = 54.7 bits (130), Expect = 2e-07
Identities = 34/128 (26%), Positives = 72/128 (56%), Gaps = 16/128 (12%)
Query: 17 KYRAALKKEKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQLEEEKLLERERQRLHEEWL 76
K L+ + ++K RQ L LR +KEE E QL +K+ E +R+RL E L
Sbjct: 521 KRNTPLRMDPKEKERQRLENLR-----RKEEAE-------QLRRQKVEEDKRRRLEEVKL 568
Query: 77 LREQKAQEEFRIKKEKEEAAKKRQEEQERKLKEQWEEQQRKEREEEEQKRQEKKEKEEAL 136
RE++ ++ + + E ++ +EE+++++++++ + K + +E++ E+K K++A
Sbjct: 569 KREERLRKVLQAR----ERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAA 624
Query: 137 QKMLDQAE 144
K +++ E
Sbjct: 625 AKKMEEVE 632
Score = 54.7 bits (130), Expect = 2e-07
Identities = 35/123 (28%), Positives = 76/123 (61%), Gaps = 9/123 (7%)
Query: 27 RKKRRQELARLRDSGLSQK--EEEEDTFIEEQQLEEEKLLERERQRLHEEWLLREQKAQE 84
+KK+ +E RLR + +++ E+ E E+++ E+E+ RE++R +E +E++ E
Sbjct: 661 QKKKEEEQERLRKAAEAKRLAEQREQERREQERREQER---REQERREQERREQERQLAE 717
Query: 85 EFRIKKEKEEAAKKRQEEQERKLKEQWEEQQR----KEREEEEQKRQEKKEKEEALQKML 140
+ R ++++ A++ +E+E+ L+ Q E+ QR K+++EE+Q+ E++ +EE +K
Sbjct: 718 QERRREQERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAK 777
Query: 141 DQA 143
+ A
Sbjct: 778 EAA 780
Score = 50.8 bits (120), Expect = 3e-06
Identities = 35/119 (29%), Positives = 70/119 (58%), Gaps = 11/119 (9%)
Query: 25 EKRKKRRQELARLRDSGLSQKEEEEDTFIEEQQLEEEKLLERERQRLHEEWLLREQKAQE 84
E+R++ R+E R Q+ E++ +E+QL E++ RE++RL E L+E+ ++
Sbjct: 682 EQREQERREQERREQERREQERREQERREQERQLAEQER-RREQERLQAERELQER--EK 738
Query: 85 EFRIKKEK--EEAAKKRQEEQERKLKEQWEEQQRKEREEEEQKRQEKKEKEEALQKMLD 141
R++KE+ E +K+++E++++L E R+ +EE+E+K +E +AL +D
Sbjct: 739 ALRLQKEQLQRELEEKKKKEEQQRLAE------RQLQEEQEKKAKEAAGASKALNVTVD 791
Score = 39.7 bits (91), Expect = 0.006
Identities = 27/106 (25%), Positives = 54/106 (50%), Gaps = 4/106 (3%)
Query: 65 ERERQRLHEEWLLREQKAQEEFRIKKEKEEAAKKRQEEQERKLKEQWEEQQRKEREEEEQ 124
E+ERQRL LR ++ E+ R +++ EE ++R EE + K +E+ + + E+
Sbjct: 532 EKERQRLEN---LRRKEEAEQLR-RQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQM 587
Query: 125 KRQEKKEKEEALQKMLDQAENELENGTTWQNPEPPVDFRVMEKDRA 170
K ++KK+ E+ ++ ++ E E + + + ME+ A
Sbjct: 588 KEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEA 633
Score = 35.4 bits (80), Expect = 0.12
Identities = 24/67 (35%), Positives = 33/67 (49%), Gaps = 2/67 (2%)
Query: 394 ESERKSSRHRGKKSH--KRTSKSRERHNSRSRGRNRDRSRDRSRGRGSRSRSRSRSRRSR 451
E+ER +R K+ +T + R R +D +RD R R SR +SRS SR
Sbjct: 40 EAERMFTREFSKEPELMPKTPSQKNRRKKRRISYVQDENRDPIRRRLSRRKSRSSQLSSR 99
Query: 452 RSRSQSS 458
R RS+ S
Sbjct: 100 RLRSKDS 106
Score = 34.3 bits (77), Expect = 0.26
Identities = 20/66 (30%), Positives = 39/66 (59%), Gaps = 7/66 (10%)
Query: 90 KEKEEAAK---KRQEEQERKLKEQWEEQQRKEREEEEQKRQEKKEK----EEALQKMLDQ 142
KEKE +R+EE E+ +++ EE +R+ EE + KR+E+ K E +++M ++
Sbjct: 531 KEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEE 590
Query: 143 AENELE 148
+ ++E
Sbjct: 591 KKKQIE 596
Score = 30.4 bits (67), Expect = 3.7
Identities = 16/90 (17%), Positives = 41/90 (45%), Gaps = 1/90 (1%)
Query: 394 ESERKSSRHRGKKSHKRTSKSRERHNSRSRGRNRDRSRDRSRGRGSRS-RSRSRSRRSRR 452
E ER+ R ++ ++ + +ER + ++R R++ R + R + R ++ R ++
Sbjct: 685 EQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQK 744
Query: 453 SRSQSSSRSRSRGRRRSGNRDRTVQSPKSK 482
+ Q + + + +R +Q + K
Sbjct: 745 EQLQRELEEKKKKEEQQRLAERQLQEEQEK 774
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.129 0.376
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,864,039
Number of Sequences: 37866
Number of extensions: 1161073
Number of successful extensions: 68961
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1481
Number of HSP's successfully gapped in prelim test: 1140
Number of HSP's that attempted gapping in prelim test: 11053
Number of HSP's gapped (non-prelim): 21901
length of query: 482
length of database: 18,247,518
effective HSP length: 106
effective length of query: 376
effective length of database: 14,233,722
effective search space: 5351879472
effective search space used: 5351879472
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.