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Search of human proteins with 4826914
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4826914 JMJD7-PLA2G4B protein [Homo sapiens]
(1012 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4826914 JMJD7-PLA2G4B protein [Homo sapiens] 2077 0.0
gi|167860120 phospholipase A2, group IVB [Homo sapiens] 1592 0.0
gi|116174754 phospholipase A2, group IVD [Homo sapiens] 766 0.0
gi|122937428 phospholipase A2, group 4E [Homo sapiens] 628 e-179
gi|67972429 phospholipase A2, group IVF [Homo sapiens] 584 e-166
gi|167860114 jumonji domain containing 7 [Homo sapiens] 490 e-138
gi|23943920 cytosolic phospholipase A2, group IVA [Homo sapiens] 241 3e-63
gi|226693363 phospholipase A2, group IVC isoform 3 [Homo sapiens] 165 2e-40
gi|226693357 phospholipase A2, group IVC isoform 2 precursor [Ho... 165 2e-40
gi|226693354 phospholipase A2, group IVC isoform 1 precursor [Ho... 165 2e-40
gi|223942018 jumonji domain containing 5 isoform 1 [Homo sapiens] 67 1e-10
gi|223942014 jumonji domain containing 5 isoform 2 [Homo sapiens] 67 1e-10
gi|38570146 synaptotagmin VII [Homo sapiens] 57 1e-07
gi|222352090 neural precursor cell expressed, developmentally do... 54 1e-06
gi|222352088 neural precursor cell expressed, developmentally do... 54 1e-06
gi|45504376 synaptotagmin VI [Homo sapiens] 54 1e-06
gi|21361472 neural precursor cell expressed, developmentally dow... 53 1e-06
gi|222352086 neural precursor cell expressed, developmentally do... 53 1e-06
gi|114520609 neural precursor cell expressed, developmentally do... 53 1e-06
gi|239743309 PREDICTED: similar to calcium-promoted Ras inactiva... 52 3e-06
gi|239743307 PREDICTED: similar to calcium-promoted Ras inactiva... 52 3e-06
gi|239508992 PREDICTED: similar to calcium-promoted Ras inactiva... 52 3e-06
gi|239508990 PREDICTED: similar to calcium-promoted Ras inactiva... 52 3e-06
gi|121114292 RAS p21 protein activator 4 isoform 2 [Homo sapiens] 52 3e-06
gi|121114294 RAS p21 protein activator 4 isoform 1 [Homo sapiens] 52 3e-06
gi|122937247 unc-13 homolog A [Homo sapiens] 50 8e-06
gi|110611226 UNC13 (C. elegans)-like [Homo sapiens] 49 2e-05
gi|122937514 unc-13 homolog C [Homo sapiens] 49 3e-05
gi|39752671 synaptotagmin X [Homo sapiens] 48 4e-05
gi|227496489 multiple C2 domains, transmembrane 2 isoform 2 [Hom... 47 9e-05
>gi|4826914 JMJD7-PLA2G4B protein [Homo sapiens]
Length = 1012
Score = 2077 bits (5381), Expect = 0.0
Identities = 1012/1012 (100%), Positives = 1012/1012 (100%)
Query: 1 MAEAALEAVRSELREFPAAARELCVPLAVPYLDKPPTPLHFYRDWVCPNRPCIIRNALQH 60
MAEAALEAVRSELREFPAAARELCVPLAVPYLDKPPTPLHFYRDWVCPNRPCIIRNALQH
Sbjct: 1 MAEAALEAVRSELREFPAAARELCVPLAVPYLDKPPTPLHFYRDWVCPNRPCIIRNALQH 60
Query: 61 WPALQKWSLPYFRATVGSTEVSVAVTPDGYADAVRGDRFMMPAERRLPLSFVLDVLEGRA 120
WPALQKWSLPYFRATVGSTEVSVAVTPDGYADAVRGDRFMMPAERRLPLSFVLDVLEGRA
Sbjct: 61 WPALQKWSLPYFRATVGSTEVSVAVTPDGYADAVRGDRFMMPAERRLPLSFVLDVLEGRA 120
Query: 121 QHPGVLYVQKQCSNLPSELPQLLPDLESHVPWASEALGKMPDAVNFWLGEAAAVTSLHKD 180
QHPGVLYVQKQCSNLPSELPQLLPDLESHVPWASEALGKMPDAVNFWLGEAAAVTSLHKD
Sbjct: 121 QHPGVLYVQKQCSNLPSELPQLLPDLESHVPWASEALGKMPDAVNFWLGEAAAVTSLHKD 180
Query: 181 HYENLYCVVSGEKHFLFHPPSDRPFIPYELYTPATYQLTEEGTFKVVDEEAMEKAEVSRT 240
HYENLYCVVSGEKHFLFHPPSDRPFIPYELYTPATYQLTEEGTFKVVDEEAMEKAEVSRT
Sbjct: 181 HYENLYCVVSGEKHFLFHPPSDRPFIPYELYTPATYQLTEEGTFKVVDEEAMEKAEVSRT 240
Query: 241 CLLTVRVLQAHRLPSKDLVTPSDCYVTLWLPTACSHRLQTRTVKNSSSPVWNQSFHFRIH 300
CLLTVRVLQAHRLPSKDLVTPSDCYVTLWLPTACSHRLQTRTVKNSSSPVWNQSFHFRIH
Sbjct: 241 CLLTVRVLQAHRLPSKDLVTPSDCYVTLWLPTACSHRLQTRTVKNSSSPVWNQSFHFRIH 300
Query: 301 RQLKNVMELKVFDQDLVTGDDPVLSVLFDAGTLRAGEFRRESFSLSPQGEGRLEVEFRLQ 360
RQLKNVMELKVFDQDLVTGDDPVLSVLFDAGTLRAGEFRRESFSLSPQGEGRLEVEFRLQ
Sbjct: 301 RQLKNVMELKVFDQDLVTGDDPVLSVLFDAGTLRAGEFRRESFSLSPQGEGRLEVEFRLQ 360
Query: 361 SLADRGEWLVSNGVLVARELSCLHVQLEETGDQKSSEHRVQLVVPGSCEGPQEASVGTGT 420
SLADRGEWLVSNGVLVARELSCLHVQLEETGDQKSSEHRVQLVVPGSCEGPQEASVGTGT
Sbjct: 361 SLADRGEWLVSNGVLVARELSCLHVQLEETGDQKSSEHRVQLVVPGSCEGPQEASVGTGT 420
Query: 421 FRFHCPACWEQELSIRLQDAPEEQLKAPLSALPSGQVVRLVFPTSQEPLMRVELKKEAGL 480
FRFHCPACWEQELSIRLQDAPEEQLKAPLSALPSGQVVRLVFPTSQEPLMRVELKKEAGL
Sbjct: 421 FRFHCPACWEQELSIRLQDAPEEQLKAPLSALPSGQVVRLVFPTSQEPLMRVELKKEAGL 480
Query: 481 RELAVRLGFGPCAEEQAFLSRRKQVVAAALRQALQLDGDLQEDEIPVVAIMATGGGIRAM 540
RELAVRLGFGPCAEEQAFLSRRKQVVAAALRQALQLDGDLQEDEIPVVAIMATGGGIRAM
Sbjct: 481 RELAVRLGFGPCAEEQAFLSRRKQVVAAALRQALQLDGDLQEDEIPVVAIMATGGGIRAM 540
Query: 541 TSLYGQLAGLKELGLLDCVSYITGASGSTWALANLYEDPEWSQKDLAGPTELLKTQVTKN 600
TSLYGQLAGLKELGLLDCVSYITGASGSTWALANLYEDPEWSQKDLAGPTELLKTQVTKN
Sbjct: 541 TSLYGQLAGLKELGLLDCVSYITGASGSTWALANLYEDPEWSQKDLAGPTELLKTQVTKN 600
Query: 601 KLGVLAPSQLQRYRQELAERARLGYPSCFTNLWALINEALLHDEPHDHKLSDQREALSHG 660
KLGVLAPSQLQRYRQELAERARLGYPSCFTNLWALINEALLHDEPHDHKLSDQREALSHG
Sbjct: 601 KLGVLAPSQLQRYRQELAERARLGYPSCFTNLWALINEALLHDEPHDHKLSDQREALSHG 660
Query: 661 QNPLPIYCALNTKGQSLTTFEFGEWCEFSPYEVGFPKYGAFIPSELFGSEFFMGQLMKRL 720
QNPLPIYCALNTKGQSLTTFEFGEWCEFSPYEVGFPKYGAFIPSELFGSEFFMGQLMKRL
Sbjct: 661 QNPLPIYCALNTKGQSLTTFEFGEWCEFSPYEVGFPKYGAFIPSELFGSEFFMGQLMKRL 720
Query: 721 PESRICFLEGIWSNLYAANLQDSLYWASEPSQFWDRWVRNQANLDKEQVPLLKIEEPPST 780
PESRICFLEGIWSNLYAANLQDSLYWASEPSQFWDRWVRNQANLDKEQVPLLKIEEPPST
Sbjct: 721 PESRICFLEGIWSNLYAANLQDSLYWASEPSQFWDRWVRNQANLDKEQVPLLKIEEPPST 780
Query: 781 AGRIAEFFTDLLTWRPLAQATHNFLRGLHFHKDYFQHPHFSTWKATTLDGLPNQLTPSEP 840
AGRIAEFFTDLLTWRPLAQATHNFLRGLHFHKDYFQHPHFSTWKATTLDGLPNQLTPSEP
Sbjct: 781 AGRIAEFFTDLLTWRPLAQATHNFLRGLHFHKDYFQHPHFSTWKATTLDGLPNQLTPSEP 840
Query: 841 HLCLLDVGYLINTSCLPLLQPTRDVDLILSLDYNLHGAFQQLQLLGRFCQEQGIPFPPIS 900
HLCLLDVGYLINTSCLPLLQPTRDVDLILSLDYNLHGAFQQLQLLGRFCQEQGIPFPPIS
Sbjct: 841 HLCLLDVGYLINTSCLPLLQPTRDVDLILSLDYNLHGAFQQLQLLGRFCQEQGIPFPPIS 900
Query: 901 PSPEEQLQPRECHTFSDPTCPGAPAVLHFPLVSDSFREYSAPGVRRTPEEAAAGEVNLSS 960
PSPEEQLQPRECHTFSDPTCPGAPAVLHFPLVSDSFREYSAPGVRRTPEEAAAGEVNLSS
Sbjct: 901 PSPEEQLQPRECHTFSDPTCPGAPAVLHFPLVSDSFREYSAPGVRRTPEEAAAGEVNLSS 960
Query: 961 SDSPYHYTKVTYSQEDVDKLLHLTHYNVCNNQEQLLEALRQAVQRRRQRRPH 1012
SDSPYHYTKVTYSQEDVDKLLHLTHYNVCNNQEQLLEALRQAVQRRRQRRPH
Sbjct: 961 SDSPYHYTKVTYSQEDVDKLLHLTHYNVCNNQEQLLEALRQAVQRRRQRRPH 1012
>gi|167860120 phospholipase A2, group IVB [Homo sapiens]
Length = 781
Score = 1592 bits (4121), Expect = 0.0
Identities = 779/781 (99%), Positives = 779/781 (99%)
Query: 232 MEKAEVSRTCLLTVRVLQAHRLPSKDLVTPSDCYVTLWLPTACSHRLQTRTVKNSSSPVW 291
M AEVSRTCLLTVRVLQAHRLPSKDLVTPSDCYVTLWLPTACSHRLQTRTVKNSSSPVW
Sbjct: 1 MAVAEVSRTCLLTVRVLQAHRLPSKDLVTPSDCYVTLWLPTACSHRLQTRTVKNSSSPVW 60
Query: 292 NQSFHFRIHRQLKNVMELKVFDQDLVTGDDPVLSVLFDAGTLRAGEFRRESFSLSPQGEG 351
NQSFHFRIHRQLKNVMELKVFDQDLVTGDDPVLSVLFDAGTLRAGEFRRESFSLSPQGEG
Sbjct: 61 NQSFHFRIHRQLKNVMELKVFDQDLVTGDDPVLSVLFDAGTLRAGEFRRESFSLSPQGEG 120
Query: 352 RLEVEFRLQSLADRGEWLVSNGVLVARELSCLHVQLEETGDQKSSEHRVQLVVPGSCEGP 411
RLEVEFRLQSLADRGEWLVSNGVLVARELSCLHVQLEETGDQKSSEHRVQLVVPGSCEGP
Sbjct: 121 RLEVEFRLQSLADRGEWLVSNGVLVARELSCLHVQLEETGDQKSSEHRVQLVVPGSCEGP 180
Query: 412 QEASVGTGTFRFHCPACWEQELSIRLQDAPEEQLKAPLSALPSGQVVRLVFPTSQEPLMR 471
QEASVGTGTFRFHCPACWEQELSIRLQDAPEEQLKAPLSALPSGQVVRLVFPTSQEPLMR
Sbjct: 181 QEASVGTGTFRFHCPACWEQELSIRLQDAPEEQLKAPLSALPSGQVVRLVFPTSQEPLMR 240
Query: 472 VELKKEAGLRELAVRLGFGPCAEEQAFLSRRKQVVAAALRQALQLDGDLQEDEIPVVAIM 531
VELKKEAGLRELAVRLGFGPCAEEQAFLSRRKQVVAAALRQALQLDGDLQEDEIPVVAIM
Sbjct: 241 VELKKEAGLRELAVRLGFGPCAEEQAFLSRRKQVVAAALRQALQLDGDLQEDEIPVVAIM 300
Query: 532 ATGGGIRAMTSLYGQLAGLKELGLLDCVSYITGASGSTWALANLYEDPEWSQKDLAGPTE 591
ATGGGIRAMTSLYGQLAGLKELGLLDCVSYITGASGSTWALANLYEDPEWSQKDLAGPTE
Sbjct: 301 ATGGGIRAMTSLYGQLAGLKELGLLDCVSYITGASGSTWALANLYEDPEWSQKDLAGPTE 360
Query: 592 LLKTQVTKNKLGVLAPSQLQRYRQELAERARLGYPSCFTNLWALINEALLHDEPHDHKLS 651
LLKTQVTKNKLGVLAPSQLQRYRQELAERARLGYPSCFTNLWALINEALLHDEPHDHKLS
Sbjct: 361 LLKTQVTKNKLGVLAPSQLQRYRQELAERARLGYPSCFTNLWALINEALLHDEPHDHKLS 420
Query: 652 DQREALSHGQNPLPIYCALNTKGQSLTTFEFGEWCEFSPYEVGFPKYGAFIPSELFGSEF 711
DQREALSHGQNPLPIYCALNTKGQSLTTFEFGEWCEFSPYEVGFPKYGAFIPSELFGSEF
Sbjct: 421 DQREALSHGQNPLPIYCALNTKGQSLTTFEFGEWCEFSPYEVGFPKYGAFIPSELFGSEF 480
Query: 712 FMGQLMKRLPESRICFLEGIWSNLYAANLQDSLYWASEPSQFWDRWVRNQANLDKEQVPL 771
FMGQLMKRLPESRICFLEGIWSNLYAANLQDSLYWASEPSQFWDRWVRNQANLDKEQVPL
Sbjct: 481 FMGQLMKRLPESRICFLEGIWSNLYAANLQDSLYWASEPSQFWDRWVRNQANLDKEQVPL 540
Query: 772 LKIEEPPSTAGRIAEFFTDLLTWRPLAQATHNFLRGLHFHKDYFQHPHFSTWKATTLDGL 831
LKIEEPPSTAGRIAEFFTDLLTWRPLAQATHNFLRGLHFHKDYFQHPHFSTWKATTLDGL
Sbjct: 541 LKIEEPPSTAGRIAEFFTDLLTWRPLAQATHNFLRGLHFHKDYFQHPHFSTWKATTLDGL 600
Query: 832 PNQLTPSEPHLCLLDVGYLINTSCLPLLQPTRDVDLILSLDYNLHGAFQQLQLLGRFCQE 891
PNQLTPSEPHLCLLDVGYLINTSCLPLLQPTRDVDLILSLDYNLHGAFQQLQLLGRFCQE
Sbjct: 601 PNQLTPSEPHLCLLDVGYLINTSCLPLLQPTRDVDLILSLDYNLHGAFQQLQLLGRFCQE 660
Query: 892 QGIPFPPISPSPEEQLQPRECHTFSDPTCPGAPAVLHFPLVSDSFREYSAPGVRRTPEEA 951
QGIPFPPISPSPEEQLQPRECHTFSDPTCPGAPAVLHFPLVSDSFREYSAPGVRRTPEEA
Sbjct: 661 QGIPFPPISPSPEEQLQPRECHTFSDPTCPGAPAVLHFPLVSDSFREYSAPGVRRTPEEA 720
Query: 952 AAGEVNLSSSDSPYHYTKVTYSQEDVDKLLHLTHYNVCNNQEQLLEALRQAVQRRRQRRP 1011
AAGEVNLSSSDSPYHYTKVTYSQEDVDKLLHLTHYNVCNNQEQLLEALRQAVQRRRQRRP
Sbjct: 721 AAGEVNLSSSDSPYHYTKVTYSQEDVDKLLHLTHYNVCNNQEQLLEALRQAVQRRRQRRP 780
Query: 1012 H 1012
H
Sbjct: 781 H 781
>gi|116174754 phospholipase A2, group IVD [Homo sapiens]
Length = 818
Score = 766 bits (1979), Expect = 0.0
Identities = 403/797 (50%), Positives = 532/797 (66%), Gaps = 28/797 (3%)
Query: 234 KAEVSRTCLLTVRVLQAHRLPSKDLVTPSDCYVTLWLPTACSHRLQTRTVKNSSSPVWNQ 293
+ E S LTVRVL+A L DL++ +D YV L L TA + +T+T+ ++S PVWN+
Sbjct: 15 QGEASTCWQLTVRVLEARNLRWADLLSEADPYVILQLSTAPGMKFKTKTLTDTSHPVWNE 74
Query: 294 SFHFRIHRQLKNVMELKVFDQDLVTGDDPVLSVLFDAGTLRAGEFRRESFSLSPQGEGRL 353
+F F I Q+KNV+EL ++D+D VT DD VL+D + G+ R++FS SPQGE L
Sbjct: 75 AFRFLIQSQVKNVLELSIYDEDSVTEDDICFKVLYDISEVLPGKLLRKTFSQSPQGEEEL 134
Query: 354 EVEFRLQSLADRGEWLVSNGVLVARELSCLHVQLEETG------DQKSSEHRVQLVVPGS 407
+VEF ++ +DR E L++N V+VARELSCL V L+ TG DQ E ++LV+ GS
Sbjct: 135 DVEFLMEETSDRPENLITNKVIVARELSCLDVHLDSTGSTAVVADQDKLE--LELVLKGS 192
Query: 408 CEGPQEASVGTGT-FRFHCPACWEQELSIRLQ---------DAPEEQLKAPLSALPSGQV 457
E Q + +GT + FRFH A E ELS RL+ D L PL L G+
Sbjct: 193 YEDTQTSFLGTASAFRFHYMAALETELSGRLRSSRSNGWNGDNSAGYLTVPLRPLTIGKE 252
Query: 458 VRLVFPTSQEPLMRVELKKEAGLRELAVRLGFGPCAEEQAFLSRRKQVVAAALRQALQLD 517
V + P P +R++LK E ELAV LGF CAEEQAFLSRRKQVVA AL+QALQLD
Sbjct: 253 VTMDVPAPNAPGVRLQLKAEGCPEELAVHLGFNLCAEEQAFLSRRKQVVAKALKQALQLD 312
Query: 518 GDLQEDEIPVVAIMATGGGIRAMTSLYGQLAGLKELGLLDCVSYITGASGSTWALANLYE 577
DLQEDE+PVV IMATGGG RAMTSLYG L L++LGLLDCV+Y +G SGSTW +A+LY
Sbjct: 313 RDLQEDEVPVVGIMATGGGARAMTSLYGHLLALQKLGLLDCVTYFSGISGSTWTMAHLYG 372
Query: 578 DPEWSQKDLAGPTELLKTQVTKNKLGVLAPSQLQRYRQELAERARLGYPSCFTNLWALIN 637
DPEWSQ+DL GP + + K+KL V +P +L YR+EL RA G+P+ F +LWAL+
Sbjct: 373 DPEWSQRDLEGPIRYAREHLAKSKLEVFSPERLASYRRELELRAEQGHPTTFVDLWALVL 432
Query: 638 EALLHDEPHDHKLSDQREALSHGQNPLPIYCALNTKGQSLTTFEFGEWCEFSPYEVGFPK 697
E++LH + D KLS QR AL GQNPLP+Y +LN K +L T +F EW EFSPYEVGF K
Sbjct: 433 ESMLHGQVMDQKLSGQRAALERGQNPLPLYLSLNVKENNLETLDFKEWVEFSPYEVGFLK 492
Query: 698 YGAFIPSELFGSEFFMGQLMKRLPESRICFLEGIWSNLYAANLQDSLYWASEPSQFWDRW 757
YGAF+P ELFGSEFFMG+LM+R+PE RICFLE IWSN+++ NL D+ Y + + W +
Sbjct: 493 YGAFVPPELFGSEFFMGRLMRRIPEPRICFLEAIWSNIFSLNLLDAWYDLTSSGESWKQH 552
Query: 758 VRNQA-NLDKEQVPLLKIEE-------PPSTAGRIAEFFTDLLTWRPLAQATHNFLRGLH 809
++++ +L+KE + P TA +A+ F LT RPL Q + NFL+GL
Sbjct: 553 IKDKTRSLEKEPLTTSGTSSRLEASWLQPGTA--LAQAFKGFLTGRPLHQRSPNFLQGLQ 610
Query: 810 FHKDYFQHPHFSTWKATTLDGLPNQLTPSEPHLCLLDVGYLINTSCLPLLQPTRDVDLIL 869
H+DY H FSTW LD +P+QLTP EP LCL+D Y INTS + +P R +DLIL
Sbjct: 611 LHQDYCSHKDFSTWADYQLDSMPSQLTPKEPRLCLVDAAYFINTSSPSMFRPGRRLDLIL 670
Query: 870 SLDYNLHGAFQQLQLLGRFCQEQGIPFPPISPSPEEQLQPRECHTFSDPTCPGAPAVLHF 929
S DY+L F+ LQ +C+ +G+PFP + PSP++Q QPRECH FSDP CP AP +LHF
Sbjct: 671 SFDYSLSAPFEALQQTELYCRARGLPFPRVEPSPQDQHQPRECHLFSDPACPEAPILLHF 730
Query: 930 PLVSDSFREYSAPGVRRTPEEAAAGEVNLSSSDSPYHYTKVTYSQEDVDKLLHLTHYNVC 989
PLV+ SF+++SAPGV+R+P E G+V+L+ + PY + +TY +ED ++LL L+ YNV
Sbjct: 731 PLVNASFKDHSAPGVQRSPAELQGGQVDLTGATCPYTLSNMTYKEEDFERLLRLSDYNVQ 790
Query: 990 NNQEQLLEALRQAVQRR 1006
+Q +L+ALR A++ R
Sbjct: 791 TSQGAILQALRTALKHR 807
>gi|122937428 phospholipase A2, group 4E [Homo sapiens]
Length = 839
Score = 628 bits (1619), Expect = e-179
Identities = 346/786 (44%), Positives = 476/786 (60%), Gaps = 46/786 (5%)
Query: 259 VTPSDCYVTLWLPTACSHRLQTRTVKNSSSPVWNQSFHFRIHRQLKNVMELKVFDQDLVT 318
V+ +DC+V+LWLPTA +L+TRT+ N +P WN+SF+F+I ++KNV+EL V D+D VT
Sbjct: 57 VSQTDCFVSLWLPTASQKKLRTRTISNCPNPEWNESFNFQIQSRVKNVLELSVCDEDTVT 116
Query: 319 GDDPVLSVLFDAGTLRAGEFRRESFSLSPQGEGRLEVEFRLQSLADRGEWLVSNGVLVAR 378
DD +L+VL+D L + F L+PQG LEVEF L+ E LV+NGVLV+R
Sbjct: 117 PDDHLLTVLYDLTKLCFRKKTHVKFPLNPQGMEELEVEFLLEESPSPPETLVTNGVLVSR 176
Query: 379 ELSCLHVQLEETGDQKSSEHRVQLV-VPGSCEG------------PQEASVGTGTFRFHC 425
++SCL V + +K + + LV V S E P A T FH
Sbjct: 177 QVSCLEVHAQSRRRRKREKMKDLLVMVNESFENTQRVRPCLEPCCPTSACFQTAAC-FHY 235
Query: 426 PACWEQELSIRL-----------QDAPEEQLKAPLSALPSGQVVRLVFPTSQEPLMRVEL 474
P ++ ++ + + + + + PL L GQV+ L S E + +
Sbjct: 236 PKYFQSQVHVEVPKSHWSCGLCCRSRKKGPISQPLDCLSDGQVMTLPVGESYE----LHM 291
Query: 475 KKEAGLRELAVRLGFGPCAEEQAFLSRRKQVVAAALRQALQLDGDLQEDEIPVVAIMATG 534
K L VRLGF C E FL +RK VVA AL+Q LQL+ DLQEDE+P++AIMATG
Sbjct: 292 KSTPCPETLDVRLGFSLCPAELEFLQKRKVVVAKALKQVLQLEEDLQEDEVPLIAIMATG 351
Query: 535 GGIRAMTSLYGQLAGLKELGLLDCVSYITGASGSTWALANLYEDPEWSQKDLAGPTELLK 594
GG R+MTS+YG L GL++L LLDC SYITG SG+TW +A LY DP+WS K+L +
Sbjct: 352 GGTRSMTSMYGHLLGLQKLNLLDCASYITGLSGATWTMATLYRDPDWSSKNLEPAIFEAR 411
Query: 595 TQVTKNKLGVLAPSQLQRYRQELAERARLGYPSCFTNLWALINEALLHDEPHDHKLSDQR 654
V K+KL L P QL+++++EL +R++ GY FT+ W L+ E L DE ++ KLSDQR
Sbjct: 412 RHVVKDKLPSLFPDQLRKFQEELRQRSQEGYRVTFTDFWGLLIETCLGDERNECKLSDQR 471
Query: 655 EALSHGQNPLPIYCALNTKGQSLTTFEFGEWCEFSPYEVGFPKYGAFIPSELFGSEFFMG 714
ALS GQNPLPIY +N K ++ +F EW EFSPYEVG KYGAFIPSELFGSEFFMG
Sbjct: 472 AALSCGQNPLPIYLTINVK-DDVSNQDFREWFEFSPYEVGLQKYGAFIPSELFGSEFFMG 530
Query: 715 QLMKRLPESRICFLEGIWSNLYAANLQDSLYWASEPSQFWDRWVRNQANLDKEQVPLLKI 774
+L+KR+PESRIC++ G+WS++++ NL D+ + +F+ RW R + D E P+L
Sbjct: 531 RLVKRIPESRICYMLGLWSSIFSLNLLDAWNLSHTSEEFFHRWTREKVQ-DIEDEPIL-- 587
Query: 775 EEPPSTAGRIAE------------FFTDLLTWRPLAQATHNFLRGLHFHKDYFQHPHFST 822
E P I E F ++LT R HNFL GL H +Y Q+ FS
Sbjct: 588 PEIPKCDANILETTVVIPGSWLSNSFREILTHRSFVSEFHNFLSGLQLHTNYLQNGQFSR 647
Query: 823 WKATTLDGLPNQLTPSEPHLCLLDVGYLINTSCLPLLQPTRDVDLILSLDYNLHGAFQQL 882
WK T LDG PNQLT S HLCLLD + +N+S PLL+P R DLI+ L+Y + L
Sbjct: 648 WKDTVLDGFPNQLTESANHLCLLDTAFFVNSSYPPLLRPERKADLIIHLNYCAGSQTKPL 707
Query: 883 QLLGRFCQEQGIPFPPISPSPEEQLQPRECHTFSDPTCPGAPAVLHFPLVSDSFREYSAP 942
+ +C Q IPFP P+E +EC+ +P P AP V FPL++D+FR+Y AP
Sbjct: 708 KQTCEYCTVQNIPFPKYE-LPDENENLKECYLMENPQEPDAPIVTFFPLINDTFRKYKAP 766
Query: 943 GVRRTPEEAAAGEVNLSSSDSPYHYTKVTYSQEDVDKLLHLTHYNVCNNQEQLLEALRQA 1002
GV R+PEE G+V++ +PY ++TY++ DKL+ L+ YN+ NN++ LL+ALR A
Sbjct: 767 GVERSPEELEQGQVDIYGPKTPYATKELTYTEATFDKLVKLSEYNILNNKDTLLQALRLA 826
Query: 1003 VQRRRQ 1008
V+++++
Sbjct: 827 VEKKKR 832
>gi|67972429 phospholipase A2, group IVF [Homo sapiens]
Length = 849
Score = 584 bits (1506), Expect = e-166
Identities = 336/803 (41%), Positives = 465/803 (57%), Gaps = 40/803 (4%)
Query: 243 LTVRVLQAHRLPSKDLVTPSDCYVTLWLPTACSHRLQTRTVKNSSSPVWNQSFHFRIHRQ 302
L V+VL+A + DL++ +DCYV LWLPTA QTR V N S P WN++FH++IH
Sbjct: 46 LQVKVLRATNIRGTDLLSKADCYVQLWLPTASPSPAQTRIVANCSDPEWNETFHYQIHGA 105
Query: 303 LKNVMELKVFDQDLVTGDDPVLSVLFDAGTLRAGEFRRESFSLSPQGEGRLEVEFRLQSL 362
+KNV+EL ++D+D++ G D + +LFD +L+ G+ + +F L+ Q L+VEF L+
Sbjct: 106 VKNVLELTLYDKDIL-GSDQLSLLLFDLRSLKCGQPHKHTFPLNHQDSQELQVEFVLEKS 164
Query: 363 ADRGEWLVSNGVLVARELSCLHVQLEETGD-----QKSSEHRVQLVVPGSCEGPQ----E 413
+++NGVLVA CL +Q GD ++ ++QL VPG+ E PQ +
Sbjct: 165 QVPASEVITNGVLVAHP--CLRIQGTLRGDGTAPREEYGSRQLQLAVPGAYEKPQLLPLQ 222
Query: 414 ASVGTG---TFRFHCPACWEQELSIRL-------QDAPEEQLKAPLSALPSGQVVRLVFP 463
G TF FH L + L Q P +L+A S L G ++ P
Sbjct: 223 PPTEPGLPPTFTFHVNPVLSSRLHVELMELLAAVQSGPSAELEAQTSKLGEGGILLSSLP 282
Query: 464 TSQEPLMRVEL----------KKEAGLRELAVRLGFGPCAEEQAFLSRRKQVVAAALRQA 513
QE V L K E +L +RLGF EQ FL RRKQVV+ AL+Q
Sbjct: 283 LGQEEQCSVALGEGQEVALSMKVEMSSGDLDLRLGFDLSDGEQEFLDRRKQVVSKALQQV 342
Query: 514 LQLDGDLQEDEIPVVAIMATGGGIRAMTSLYGQLAGLKELGLLDCVSYITGASGSTWALA 573
L L L ++PVVA++ +GGG RAM+SLYG LAGL+ELGLLD V+Y++G SGSTW ++
Sbjct: 343 LGLSEALDSGQVPVVAVLGSGGGTRAMSSLYGSLAGLQELGLLDTVTYLSGVSGSTWCIS 402
Query: 574 NLYEDPEWSQKDLAGPTELLKTQVTKNKLGVLAPSQLQRYRQELAERARLGYPSCFTNLW 633
LY DP WSQ L GP E + V +K+G L+ +LQ Y QEL R R G+ +LW
Sbjct: 403 TLYRDPAWSQVALQGPIERAQVHVCSSKMGALSTERLQYYTQELGVRERSGHSVSLIDLW 462
Query: 634 ALINEALLHDEPHDHKLSDQREALSHGQNPLPIYCALNTKGQSLTTFEFGEWCEFSPYEV 693
L+ E LL+ E + KLSDQ+EA+ GQNP PIY ++N + +L+ +F EWCEF+PYEV
Sbjct: 463 GLLVEYLLYQEENPAKLSDQQEAVRQGQNPYPIYTSVNVR-TNLSGEDFAEWCEFTPYEV 521
Query: 694 GFPKYGAFIPSELFGSEFFMGQLMKRLPESRICFLEGIWSNLYAANLQDSLYWASEPSQF 753
GFPKYGA++P+ELFGSE FMG+L++ PE RIC+L+G+W + +A +L + +
Sbjct: 522 GFPKYGAYVPTELFGSELFMGRLLQLQPEPRICYLQGMWGSAFATSLDEIFLKTAGSGLS 581
Query: 754 WDRWVRNQANL-DKEQVPLLKIEEPPST-----AGRIAEFFTDLLTWRPLAQATHNFLRG 807
+ W R N+ D Q P L T G ++ D+ T R + + NF RG
Sbjct: 582 FLEWYRGSVNITDDCQKPQLHNPSRLRTRLLTPQGPFSQAVLDIFTSRFTSAQSFNFTRG 641
Query: 808 LHFHKDYFQHPHFSTWKATTLDGLPNQLTPSEPHLCLLDVGYLINTSCLPLLQPTRDVDL 867
L HKDY F WK T D PNQLTP L L+D G+ IN+ L P R VDL
Sbjct: 642 LCLHKDYVAGREFVAWKDTHPDAFPNQLTPMRDCLYLVDGGFAINSPFPLALLPQRAVDL 701
Query: 868 ILSLDYNLHGAFQQLQLLGRFCQEQGIPFPPISPSPEEQLQPRECHTFSDPTCPGAPAVL 927
ILS DY+L F+ L++ ++C ++GIPFP I PE+ + REC+ F+ P +P VL
Sbjct: 702 ILSFDYSLEAPFEVLKMTEKYCLDRGIPFPSIEVGPEDVEEARECYLFAKAEDPRSPIVL 761
Query: 928 HFPLVSDSFREYSAPGV-RRTPEEAAAGEVNLSSSDSPYHYTKVTYSQEDVDKLLHLTHY 986
HFPLV+ +FR + APGV R+T EE A G+ ++ D+PY TY +D +L+ L+ Y
Sbjct: 762 HFPLVNRTFRTHLAPGVERQTAEEKAFGDFVINRPDTPYGMMNFTYEPQDFYRLVALSRY 821
Query: 987 NVCNNQEQLLEALRQAVQRRRQR 1009
NV NN E L AL+ A+ R + R
Sbjct: 822 NVLNNVETLKCALQLALDRHQAR 844
>gi|167860114 jumonji domain containing 7 [Homo sapiens]
Length = 316
Score = 490 bits (1262), Expect = e-138
Identities = 234/234 (100%), Positives = 234/234 (100%)
Query: 1 MAEAALEAVRSELREFPAAARELCVPLAVPYLDKPPTPLHFYRDWVCPNRPCIIRNALQH 60
MAEAALEAVRSELREFPAAARELCVPLAVPYLDKPPTPLHFYRDWVCPNRPCIIRNALQH
Sbjct: 1 MAEAALEAVRSELREFPAAARELCVPLAVPYLDKPPTPLHFYRDWVCPNRPCIIRNALQH 60
Query: 61 WPALQKWSLPYFRATVGSTEVSVAVTPDGYADAVRGDRFMMPAERRLPLSFVLDVLEGRA 120
WPALQKWSLPYFRATVGSTEVSVAVTPDGYADAVRGDRFMMPAERRLPLSFVLDVLEGRA
Sbjct: 61 WPALQKWSLPYFRATVGSTEVSVAVTPDGYADAVRGDRFMMPAERRLPLSFVLDVLEGRA 120
Query: 121 QHPGVLYVQKQCSNLPSELPQLLPDLESHVPWASEALGKMPDAVNFWLGEAAAVTSLHKD 180
QHPGVLYVQKQCSNLPSELPQLLPDLESHVPWASEALGKMPDAVNFWLGEAAAVTSLHKD
Sbjct: 121 QHPGVLYVQKQCSNLPSELPQLLPDLESHVPWASEALGKMPDAVNFWLGEAAAVTSLHKD 180
Query: 181 HYENLYCVVSGEKHFLFHPPSDRPFIPYELYTPATYQLTEEGTFKVVDEEAMEK 234
HYENLYCVVSGEKHFLFHPPSDRPFIPYELYTPATYQLTEEGTFKVVDEEAMEK
Sbjct: 181 HYENLYCVVSGEKHFLFHPPSDRPFIPYELYTPATYQLTEEGTFKVVDEEAMEK 234
>gi|23943920 cytosolic phospholipase A2, group IVA [Homo sapiens]
Length = 749
Score = 241 bits (615), Expect = 3e-63
Identities = 187/656 (28%), Positives = 313/656 (47%), Gaps = 75/656 (11%)
Query: 420 TFRFHCPACWEQELSIRLQDAP---EEQLKAP---LSALPSGQVVRLVFPTSQEPLMRVE 473
TF F E L I L DA +E L +S++ G+ + F +Q M +E
Sbjct: 74 TFEFILDPNQENVLEITLMDANYVMDETLGTATFTVSSMKVGEKKEVPFIFNQVTEMVLE 133
Query: 474 LKKEAGLRELAVRLGFGPCAEEQAFLSRRKQVVAAALRQAL---QLDGDLQEDEIPVVAI 530
+ E +R C +E+ F +RK+ + ++++ L +G ++PVVAI
Sbjct: 134 MSLEVCSCP-DLRFSMALCDQEKTFRQQRKEHIRESMKKLLGPKNSEGLHSARDVPVVAI 192
Query: 531 MATGGGIRAMTSLYGQLAGLKELGLLDCVSYITGASGSTWALANLYEDPEWSQKDLAGPT 590
+ +GGG RAM G + L E G+LDC +Y+ G SGSTW ++ LY P++ +K
Sbjct: 193 LGSGGGFRAMVGFSGVMKALYESGILDCATYVAGLSGSTWYMSTLYSHPDFPEKGPEEIN 252
Query: 591 ELLKTQVTKNKLGVLAPSQLQRYRQELAERARLGYPSCFTNLWA-LINEALLHDEPHDHK 649
E L V+ N L +L P +++RY + L ++ G P FT+++ LI E L+H+ +
Sbjct: 253 EELMKNVSHNPLLLLTPQKVKRYVESLWKKKSSGQPVTFTDIFGMLIGETLIHNRMNT-T 311
Query: 650 LSDQREALSHGQNPLPIYCALNTKGQSLTTFEFGEWCEFSPYEVGFPKYGAFIPSELFGS 709
LS +E ++ Q PLP++ L+ K ++ F +W EFSPYE+G KYG F+ +LFGS
Sbjct: 312 LSSLKEKVNTAQCPLPLFTCLHVK-PDVSELMFADWVEFSPYEIGMAKYGTFMAPDLFGS 370
Query: 710 EFFMGQLMKRLPESRICFLEGIWSNLYAANLQDSLYWASEPSQ----------FWDRWVR 759
+FFMG ++K+ E+ + FL G+W + ++ L + S+ + +
Sbjct: 371 KFFMGTVVKKYEENPLHFLMGVWGSAFSILFNRVLGVSGSQSRGSTMEEELENITTKHIV 430
Query: 760 NQANLDKEQVPLLKIEEPPSTAGRIA--EFFTD-------------------LLTWRPLA 798
+ + D + + EP T A ++ +D T A
Sbjct: 431 SNDSSDSDD----ESHEPKGTENEDAGSDYQSDNQASWIHRMIMALVSDSALFNTREGRA 486
Query: 799 QATHNFLRGLHFHKDYFQHP--HFSTWKATTLDGL------PNQ-------LTPSEPHLC 843
HNF+ GL+ + Y P F+T + D L P++ L +
Sbjct: 487 GKVHNFMLGLNLNTSYPLSPLSDFATQDSFDDDELDAAVADPDEFERIYEPLDVKSKKIH 546
Query: 844 LLDVGYLINTSCLPLLQPTRDVDLILSLDYNLHGA-----FQQLQLLGRFCQEQGIPFPP 898
++D G N +L+P R VDLI+S D++ + F++L L ++ + +PFP
Sbjct: 547 VVDSGLTFNLPYPLILRPQRGVDLIISFDFSARPSDSSPPFKELLLAEKWAKMNKLPFPK 606
Query: 899 ISPSPEEQLQPRECHTFSDPTCP----GAPAVLHFPLVSDSFREYSAPGV-RRTPEEAAA 953
I P ++ +EC+ F P P P ++HF L + +FR+Y APGV R T EE
Sbjct: 607 IDPYVFDREGLKECYVFK-PKNPDMEKDCPTIIHFVLANINFRKYKAPGVPRETEEEKEI 665
Query: 954 GEVNL-SSSDSPYHYTKVTYSQEDVDKLLHLTHYNVCNNQEQLLEALRQAVQRRRQ 1008
+ ++ +SP+ Y + +L L H+N NN + + EA+ ++++ RRQ
Sbjct: 666 ADFDIFDDPESPFSTFNFQYPNQAFKRLHDLMHFNTLNNIDVIKEAMVESIEYRRQ 721
Score = 56.2 bits (134), Expect = 1e-07
Identities = 36/124 (29%), Positives = 63/124 (50%), Gaps = 4/124 (3%)
Query: 244 TVRVLQAHRLPSK---DLVTPSDCYVTLWLPTACSHRLQTRTVKNSSSPVWNQSFHFRIH 300
TV VL+A ++ D++ D YV L++ T R +TR N +PVWN++F F +
Sbjct: 21 TVVVLRATKVTKGAFGDMLDTPDPYVELFISTTPDSRKRTRHFNNDINPVWNETFEFILD 80
Query: 301 RQLKNVMELKVFDQDLVTGDDPVLSVLFDAGTLRAGEFRRESFSLSPQGEGRLEVEFRLQ 360
+NV+E+ + D + V D+ + + F +++ GE + F + E LE+ +
Sbjct: 81 PNQENVLEITLMDANYVM-DETLGTATFTVSSMKVGEKKEVPFIFNQVTEMVLEMSLEVC 139
Query: 361 SLAD 364
S D
Sbjct: 140 SCPD 143
>gi|226693363 phospholipase A2, group IVC isoform 3 [Homo sapiens]
Length = 527
Score = 165 bits (418), Expect = 2e-40
Identities = 153/569 (26%), Positives = 241/569 (42%), Gaps = 124/569 (21%)
Query: 494 EEQAFLSRRKQVVAAALRQALQLDGDLQEDEIPVVAIMATGGGIRAMTSLYGQLAGLKEL 553
EE+A + RR+ V AL++ ++ DE PVVA++ +GGG+RA + G L+ +KE
Sbjct: 15 EEKAAVERRRLHVLKALKKLR-----IEADEAPVVAVLGSGGGLRAHIACLGVLSEMKEQ 69
Query: 554 GLLDCVSYITGASGSTWALANLYEDPEWSQKDLAGPTELLKTQVTKNKLGVLAPSQLQRY 613
GLLD V+Y+ G SGSTWA+++LY + D+ LK + T+ + L +
Sbjct: 70 GLLDAVTYLAGVSGSTWAISSLYT----NDGDMEALEADLKHRFTRQEW------DLAKS 119
Query: 614 RQELAERARLGYPSCFTNLWA-LINEALLHDEPHDHKLSDQREALSHGQNPLPIYCALNT 672
Q+ + AR S T+ WA ++ + P H LS+ ++ + G P PI+ A++
Sbjct: 120 LQKTIQAARSENYS-LTDFWAYMVISKQTRELPESH-LSNMKKPVEEGTLPYPIFAAIDN 177
Query: 673 KGQ-SLTTFEFGE-WCEFSPYEVGFPKYGAFIPSELFGSEFFMGQLMKRLPESRICFLEG 730
Q S E W EF+P+ GF GAF+ FGS+F G+L++ PE + FL G
Sbjct: 178 DLQPSWQEARAPETWFEFTPHHAGFSALGAFVSITHFGSKFKKGRLVRTHPERDLTFLRG 237
Query: 731 IWSNLYA-------------ANLQDSLYW------------------------------- 746
+W + NL W
Sbjct: 238 LWGSALGNTEVIREYIFDQLRNLTLKGLWRRAVANAKSIGHLIFARLLRLQESSQGEHPP 297
Query: 747 ----ASEPSQFW-----DRWVRNQANLDKEQVPLLKIEEPPSTAGRIAEFF-----TDLL 792
EP W + W R +L+K++ P E P G ++ T +
Sbjct: 298 PEDEGGEPEHTWLTEMLENWTR--TSLEKQEQP----HEDPERKGSLSNLMDFVKKTGIC 351
Query: 793 TWRPLAQATHNFLRGLHFHKDYFQHPHFSTWKATTLDGLPNQLTPSEPHLCLLDVGYLIN 852
+ THNFL ++H G+ +++ S HL L+D G IN
Sbjct: 352 ASKWEWGTTHNFL---------YKH-----------GGIRDKIMSSRKHLHLVDAGLAIN 391
Query: 853 TSCLPLLQPTRDVDLILSLDYNLHGAFQQLQLLGRFCQEQGIPFPPISPSPEE--QLQPR 910
T +L PTR+V LILS D++ F+ ++ +C+ IPFP + + + P
Sbjct: 392 TPFPLVLPPTREVHLILSFDFSAGDPFETIRATTDYCRRHKIPFPQVEEAELDLWSKAPA 451
Query: 911 ECHTFSDPTCPGAPAVLHFPLVSDSFREYSAPGVRRTPEEAAAGEVNLSSSDSPYHYTKV 970
C+ T P V+HFPL + +A G++ S
Sbjct: 452 SCYILKGET---GPVVMHFPLFN---------------IDACGGDIEAWSDTYDTFKLAD 493
Query: 971 TYSQEDVDKLLHLTHYNVCNNQEQLLEAL 999
TY+ + V LL L NV N++++L L
Sbjct: 494 TYTLDVVVLLLALAKKNVRENKKKILREL 522
>gi|226693357 phospholipase A2, group IVC isoform 2 precursor [Homo
sapiens]
Length = 551
Score = 165 bits (418), Expect = 2e-40
Identities = 153/569 (26%), Positives = 241/569 (42%), Gaps = 124/569 (21%)
Query: 494 EEQAFLSRRKQVVAAALRQALQLDGDLQEDEIPVVAIMATGGGIRAMTSLYGQLAGLKEL 553
EE+A + RR+ V AL++ ++ DE PVVA++ +GGG+RA + G L+ +KE
Sbjct: 25 EEKAAVERRRLHVLKALKKLR-----IEADEAPVVAVLGSGGGLRAHIACLGVLSEMKEQ 79
Query: 554 GLLDCVSYITGASGSTWALANLYEDPEWSQKDLAGPTELLKTQVTKNKLGVLAPSQLQRY 613
GLLD V+Y+ G SGSTWA+++LY + D+ LK + T+ + L +
Sbjct: 80 GLLDAVTYLAGVSGSTWAISSLYT----NDGDMEALEADLKHRFTRQEW------DLAKS 129
Query: 614 RQELAERARLGYPSCFTNLWA-LINEALLHDEPHDHKLSDQREALSHGQNPLPIYCALNT 672
Q+ + AR S T+ WA ++ + P H LS+ ++ + G P PI+ A++
Sbjct: 130 LQKTIQAARSENYS-LTDFWAYMVISKQTRELPESH-LSNMKKPVEEGTLPYPIFAAIDN 187
Query: 673 KGQ-SLTTFEFGE-WCEFSPYEVGFPKYGAFIPSELFGSEFFMGQLMKRLPESRICFLEG 730
Q S E W EF+P+ GF GAF+ FGS+F G+L++ PE + FL G
Sbjct: 188 DLQPSWQEARAPETWFEFTPHHAGFSALGAFVSITHFGSKFKKGRLVRTHPERDLTFLRG 247
Query: 731 IWSNLYA-------------ANLQDSLYW------------------------------- 746
+W + NL W
Sbjct: 248 LWGSALGNTEVIREYIFDQLRNLTLKGLWRRAVANAKSIGHLIFARLLRLQESSQGEHPP 307
Query: 747 ----ASEPSQFW-----DRWVRNQANLDKEQVPLLKIEEPPSTAGRIAEFF-----TDLL 792
EP W + W R +L+K++ P E P G ++ T +
Sbjct: 308 PEDEGGEPEHTWLTEMLENWTR--TSLEKQEQP----HEDPERKGSLSNLMDFVKKTGIC 361
Query: 793 TWRPLAQATHNFLRGLHFHKDYFQHPHFSTWKATTLDGLPNQLTPSEPHLCLLDVGYLIN 852
+ THNFL ++H G+ +++ S HL L+D G IN
Sbjct: 362 ASKWEWGTTHNFL---------YKH-----------GGIRDKIMSSRKHLHLVDAGLAIN 401
Query: 853 TSCLPLLQPTRDVDLILSLDYNLHGAFQQLQLLGRFCQEQGIPFPPISPSPEE--QLQPR 910
T +L PTR+V LILS D++ F+ ++ +C+ IPFP + + + P
Sbjct: 402 TPFPLVLPPTREVHLILSFDFSAGDPFETIRATTDYCRRHKIPFPQVEEAELDLWSKAPA 461
Query: 911 ECHTFSDPTCPGAPAVLHFPLVSDSFREYSAPGVRRTPEEAAAGEVNLSSSDSPYHYTKV 970
C+ T P V+HFPL + +A G++ S
Sbjct: 462 SCYILKGET---GPVVMHFPLFN---------------IDACGGDIEAWSDTYDTFKLAD 503
Query: 971 TYSQEDVDKLLHLTHYNVCNNQEQLLEAL 999
TY+ + V LL L NV N++++L L
Sbjct: 504 TYTLDVVVLLLALAKKNVRENKKKILREL 532
>gi|226693354 phospholipase A2, group IVC isoform 1 precursor [Homo
sapiens]
Length = 541
Score = 165 bits (418), Expect = 2e-40
Identities = 153/569 (26%), Positives = 241/569 (42%), Gaps = 124/569 (21%)
Query: 494 EEQAFLSRRKQVVAAALRQALQLDGDLQEDEIPVVAIMATGGGIRAMTSLYGQLAGLKEL 553
EE+A + RR+ V AL++ ++ DE PVVA++ +GGG+RA + G L+ +KE
Sbjct: 15 EEKAAVERRRLHVLKALKKLR-----IEADEAPVVAVLGSGGGLRAHIACLGVLSEMKEQ 69
Query: 554 GLLDCVSYITGASGSTWALANLYEDPEWSQKDLAGPTELLKTQVTKNKLGVLAPSQLQRY 613
GLLD V+Y+ G SGSTWA+++LY + D+ LK + T+ + L +
Sbjct: 70 GLLDAVTYLAGVSGSTWAISSLYT----NDGDMEALEADLKHRFTRQEW------DLAKS 119
Query: 614 RQELAERARLGYPSCFTNLWA-LINEALLHDEPHDHKLSDQREALSHGQNPLPIYCALNT 672
Q+ + AR S T+ WA ++ + P H LS+ ++ + G P PI+ A++
Sbjct: 120 LQKTIQAARSENYS-LTDFWAYMVISKQTRELPESH-LSNMKKPVEEGTLPYPIFAAIDN 177
Query: 673 KGQ-SLTTFEFGE-WCEFSPYEVGFPKYGAFIPSELFGSEFFMGQLMKRLPESRICFLEG 730
Q S E W EF+P+ GF GAF+ FGS+F G+L++ PE + FL G
Sbjct: 178 DLQPSWQEARAPETWFEFTPHHAGFSALGAFVSITHFGSKFKKGRLVRTHPERDLTFLRG 237
Query: 731 IWSNLYA-------------ANLQDSLYW------------------------------- 746
+W + NL W
Sbjct: 238 LWGSALGNTEVIREYIFDQLRNLTLKGLWRRAVANAKSIGHLIFARLLRLQESSQGEHPP 297
Query: 747 ----ASEPSQFW-----DRWVRNQANLDKEQVPLLKIEEPPSTAGRIAEFF-----TDLL 792
EP W + W R +L+K++ P E P G ++ T +
Sbjct: 298 PEDEGGEPEHTWLTEMLENWTR--TSLEKQEQP----HEDPERKGSLSNLMDFVKKTGIC 351
Query: 793 TWRPLAQATHNFLRGLHFHKDYFQHPHFSTWKATTLDGLPNQLTPSEPHLCLLDVGYLIN 852
+ THNFL ++H G+ +++ S HL L+D G IN
Sbjct: 352 ASKWEWGTTHNFL---------YKH-----------GGIRDKIMSSRKHLHLVDAGLAIN 391
Query: 853 TSCLPLLQPTRDVDLILSLDYNLHGAFQQLQLLGRFCQEQGIPFPPISPSPEE--QLQPR 910
T +L PTR+V LILS D++ F+ ++ +C+ IPFP + + + P
Sbjct: 392 TPFPLVLPPTREVHLILSFDFSAGDPFETIRATTDYCRRHKIPFPQVEEAELDLWSKAPA 451
Query: 911 ECHTFSDPTCPGAPAVLHFPLVSDSFREYSAPGVRRTPEEAAAGEVNLSSSDSPYHYTKV 970
C+ T P V+HFPL + +A G++ S
Sbjct: 452 SCYILKGET---GPVVMHFPLFN---------------IDACGGDIEAWSDTYDTFKLAD 493
Query: 971 TYSQEDVDKLLHLTHYNVCNNQEQLLEAL 999
TY+ + V LL L NV N++++L L
Sbjct: 494 TYTLDVVVLLLALAKKNVRENKKKILREL 522
>gi|223942018 jumonji domain containing 5 isoform 1 [Homo sapiens]
Length = 454
Score = 66.6 bits (161), Expect = 1e-10
Identities = 50/175 (28%), Positives = 75/175 (42%), Gaps = 14/175 (8%)
Query: 29 VPYLDKPPTPLHFYRDWVCPNRPCIIRNALQHWPALQKWSLPYFRATVGSTEVSVAVTPD 88
VP L +P HF ++ P RP I++ HWP +QKWSL Y + G V V V
Sbjct: 222 VPRLHRPSLQ-HFREQFLVPGRPVILKGVADHWPCMQKWSLEYIQEIAGCRTVPVEV-GS 279
Query: 89 GYADAVRGDRFMMPAERRLPLSFVLDVLEGRAQHPGVLYVQKQCSNLPSELPQLLPDLES 148
Y D M E F+ + + G L Q Q L ++P+L D+ S
Sbjct: 280 RYTDEEWSQTLMTVNE------FISKYIVNEPRDVGYL-AQHQ---LFDQIPELKQDI-S 328
Query: 149 HVPWASEALGKMPD-AVNFWLGEAAAVTSLHKDHYENLYCVVSGEKHFLFHPPSD 202
+ S G+ + +N W G ++ LH+D +N V G K+ + P +
Sbjct: 329 IPDYCSLGDGEEEEITINAWFGPQGTISPLHQDPQQNFLVQVMGRKYIRLYSPQE 383
>gi|223942014 jumonji domain containing 5 isoform 2 [Homo sapiens]
Length = 416
Score = 66.6 bits (161), Expect = 1e-10
Identities = 50/175 (28%), Positives = 75/175 (42%), Gaps = 14/175 (8%)
Query: 29 VPYLDKPPTPLHFYRDWVCPNRPCIIRNALQHWPALQKWSLPYFRATVGSTEVSVAVTPD 88
VP L +P HF ++ P RP I++ HWP +QKWSL Y + G V V V
Sbjct: 184 VPRLHRPSLQ-HFREQFLVPGRPVILKGVADHWPCMQKWSLEYIQEIAGCRTVPVEV-GS 241
Query: 89 GYADAVRGDRFMMPAERRLPLSFVLDVLEGRAQHPGVLYVQKQCSNLPSELPQLLPDLES 148
Y D M E F+ + + G L Q Q L ++P+L D+ S
Sbjct: 242 RYTDEEWSQTLMTVNE------FISKYIVNEPRDVGYL-AQHQ---LFDQIPELKQDI-S 290
Query: 149 HVPWASEALGKMPD-AVNFWLGEAAAVTSLHKDHYENLYCVVSGEKHFLFHPPSD 202
+ S G+ + +N W G ++ LH+D +N V G K+ + P +
Sbjct: 291 IPDYCSLGDGEEEEITINAWFGPQGTISPLHQDPQQNFLVQVMGRKYIRLYSPQE 345
>gi|38570146 synaptotagmin VII [Homo sapiens]
Length = 403
Score = 56.6 bits (135), Expect = 1e-07
Identities = 35/132 (26%), Positives = 65/132 (49%), Gaps = 13/132 (9%)
Query: 243 LTVRVLQAHRLPSKDLVTPSDCYVTLWLPTACSHRLQTRTVKNSSSPVWNQSFHFR---I 299
LTV++++A LP+KD SD +V ++L H+L+T+ + + +P WN++F F
Sbjct: 152 LTVKIMKAQELPAKDFSGTSDPFVKIYLLPDKKHKLETKVKRKNLNPHWNETFLFEGFPY 211
Query: 300 HRQLKNVMELKVFDQDLVTGDDPVLSVLFDAGTLRAGEFRRESFSLSPQGEGRLEVEFRL 359
+ ++ ++ L+V D D + +DP+ V + + + L P +G
Sbjct: 212 EKVVQRILYLQVLDYDRFSRNDPIGEVSIPLNKVDLTQMQTFWKDLKPCSDGS------- 264
Query: 360 QSLADRGEWLVS 371
RGE L+S
Sbjct: 265 ---GSRGELLLS 273
Score = 38.9 bits (89), Expect = 0.025
Identities = 23/85 (27%), Positives = 47/85 (55%), Gaps = 4/85 (4%)
Query: 243 LTVRVLQAHRLPSKDLVTPSDCYVTLWL--PTACSHRLQTRTVKNSSSPVWNQSFHFRI- 299
+ V +++A L + D+ SD YV +WL + +T T+K + +P++N+SF F I
Sbjct: 283 IIVNIIKARNLKAMDIGGTSDPYVKVWLMYKDKRVEKKKTVTMKRNLNPIFNESFAFDIP 342
Query: 300 -HRQLKNVMELKVFDQDLVTGDDPV 323
+ + + + V D+D ++ +D +
Sbjct: 343 TEKLRETTIIITVMDKDKLSRNDVI 367
>gi|222352090 neural precursor cell expressed, developmentally
down-regulated 4-like isoform 5 [Homo sapiens]
Length = 947
Score = 53.5 bits (127), Expect = 1e-06
Identities = 31/90 (34%), Positives = 52/90 (57%), Gaps = 5/90 (5%)
Query: 236 EVSRTCLLTVRVLQAHRLPSKDLVTPSDCYVTLWLPTACSHR----LQTRTVKNSSSPVW 291
E + +L V+V+ L KD+ SD YV L L A +R +QT+T+K + +P W
Sbjct: 7 EQGESRILRVKVVSGIDLAKKDIFGASDPYVKLSLYVADENRELALVQTKTIKKTLNPKW 66
Query: 292 NQSFHFRIHRQLKNVMELKVFDQDLVTGDD 321
N+ F+FR++ ++ +VFD++ +T DD
Sbjct: 67 NEEFYFRVNPSNHRLL-FEVFDENRLTRDD 95
>gi|222352088 neural precursor cell expressed, developmentally
down-regulated 4-like isoform 4 [Homo sapiens]
Length = 967
Score = 53.5 bits (127), Expect = 1e-06
Identities = 31/90 (34%), Positives = 52/90 (57%), Gaps = 5/90 (5%)
Query: 236 EVSRTCLLTVRVLQAHRLPSKDLVTPSDCYVTLWLPTACSHR----LQTRTVKNSSSPVW 291
E + +L V+V+ L KD+ SD YV L L A +R +QT+T+K + +P W
Sbjct: 7 EQGESRILRVKVVSGIDLAKKDIFGASDPYVKLSLYVADENRELALVQTKTIKKTLNPKW 66
Query: 292 NQSFHFRIHRQLKNVMELKVFDQDLVTGDD 321
N+ F+FR++ ++ +VFD++ +T DD
Sbjct: 67 NEEFYFRVNPSNHRLL-FEVFDENRLTRDD 95
>gi|45504376 synaptotagmin VI [Homo sapiens]
Length = 425
Score = 53.5 bits (127), Expect = 1e-06
Identities = 44/172 (25%), Positives = 80/172 (46%), Gaps = 16/172 (9%)
Query: 243 LTVRVLQAHRLPSKDLVTPSDCYVTLWLPTACSHRLQTRTVKNSSSPVWNQSFHFRI-HR 301
L VR+L+A LP+KD SD YV ++L +LQTR + + +P ++++FHF + +
Sbjct: 161 LIVRILKAFDLPAKDFCGSSDPYVKIYLLPDRKCKLQTRVHRKTLNPTFDENFHFPVPYE 220
Query: 302 QLKN-VMELKVFDQDLVTGDDPVLSVLFDAGTLRAGEFRRESFSLSPQGEGRLEVEFRLQ 360
+L + + L VFD D + D + V+ D A + RE+ ++++
Sbjct: 221 ELADRKLHLSVFDFDRFSRHDMIGEVILD-NLFEASDLSRETSIWK-------DIQYATS 272
Query: 361 SLADRGE------WLVSNGVLVARELSCLHVQLEETGDQKSSEHRVQLVVPG 406
D GE +L + G L + C +++ + +V L+ G
Sbjct: 273 ESVDLGEIMFSLCYLPTAGRLTLTVIKCRNLKAMDITGYSDPYVKVSLLCDG 324
>gi|21361472 neural precursor cell expressed, developmentally
down-regulated 4-like isoform 3 [Homo sapiens]
Length = 955
Score = 53.1 bits (126), Expect = 1e-06
Identities = 30/84 (35%), Positives = 50/84 (59%), Gaps = 5/84 (5%)
Query: 242 LLTVRVLQAHRLPSKDLVTPSDCYVTLWLPTACSHR----LQTRTVKNSSSPVWNQSFHF 297
+L V+V+ L KD+ SD YV L L A +R +QT+T+K + +P WN+ F+F
Sbjct: 21 ILRVKVVSGIDLAKKDIFGASDPYVKLSLYVADENRELALVQTKTIKKTLNPKWNEEFYF 80
Query: 298 RIHRQLKNVMELKVFDQDLVTGDD 321
R++ ++ +VFD++ +T DD
Sbjct: 81 RVNPSNHRLL-FEVFDENRLTRDD 103
>gi|222352086 neural precursor cell expressed, developmentally
down-regulated 4-like isoform 1 [Homo sapiens]
Length = 975
Score = 53.1 bits (126), Expect = 1e-06
Identities = 30/84 (35%), Positives = 50/84 (59%), Gaps = 5/84 (5%)
Query: 242 LLTVRVLQAHRLPSKDLVTPSDCYVTLWLPTACSHR----LQTRTVKNSSSPVWNQSFHF 297
+L V+V+ L KD+ SD YV L L A +R +QT+T+K + +P WN+ F+F
Sbjct: 21 ILRVKVVSGIDLAKKDIFGASDPYVKLSLYVADENRELALVQTKTIKKTLNPKWNEEFYF 80
Query: 298 RIHRQLKNVMELKVFDQDLVTGDD 321
R++ ++ +VFD++ +T DD
Sbjct: 81 RVNPSNHRLL-FEVFDENRLTRDD 103
>gi|114520609 neural precursor cell expressed, developmentally
down-regulated 4 isoform 1 [Homo sapiens]
Length = 900
Score = 53.1 bits (126), Expect = 1e-06
Identities = 35/93 (37%), Positives = 54/93 (58%), Gaps = 6/93 (6%)
Query: 232 MEKAEVSRTCLLTVRVLQAHRLPSKDLVTPSDCYV--TLWLP-TACSHRLQTRTVKNSSS 288
+E E SR ++ VRV+ L KD++ SD YV TL+ P +QT+T+K S +
Sbjct: 12 LEDEENSR--IVRVRVIAGIGLAKKDILGASDPYVRVTLYDPMNGVLTSVQTKTIKKSLN 69
Query: 289 PVWNQSFHFRIHRQLKNVMELKVFDQDLVTGDD 321
P WN+ FR+H Q ++ +VFD++ +T DD
Sbjct: 70 PKWNEEILFRVHPQQHRLL-FEVFDENRLTRDD 101
>gi|239743309 PREDICTED: similar to calcium-promoted Ras inactivator
isoform 2 [Homo sapiens]
Length = 731
Score = 52.0 bits (123), Expect = 3e-06
Identities = 46/149 (30%), Positives = 66/149 (44%), Gaps = 7/149 (4%)
Query: 218 LTEEGTFKVVDEEAMEKAEV---SRTCLLTVRVLQAHRLPSKDLVTPSDCYVTLWLPTAC 274
LTE + V E + EV +R C L VL+A L KD SD +V +
Sbjct: 35 LTEVDPDEEVQGEIHLRLEVWPGARACRLRCSVLEARDLAPKDRNGTSDPFVRVRYK--- 91
Query: 275 SHRLQTRTVKNSSSPVWNQSFHFRIHRQLKNVMELKVFDQDLVTGDDPVLSVLFDAGTLR 334
+T VK S P WN++F F + + ++ +D DLV+ +D + V+ D LR
Sbjct: 92 GRTRETSIVKKSCYPRWNETFEFELQEGAMEALCVEAWDWDLVSRNDFLGKVVIDVQRLR 151
Query: 335 AGEFRRESFSLSP-QGEGRLEVEFRLQSL 362
+ F L P Q + R E L SL
Sbjct: 152 VVQQEEGWFRLQPDQSKSRRHDEGNLGSL 180
>gi|239743307 PREDICTED: similar to calcium-promoted Ras inactivator
isoform 1 [Homo sapiens]
Length = 757
Score = 52.0 bits (123), Expect = 3e-06
Identities = 46/149 (30%), Positives = 66/149 (44%), Gaps = 7/149 (4%)
Query: 218 LTEEGTFKVVDEEAMEKAEV---SRTCLLTVRVLQAHRLPSKDLVTPSDCYVTLWLPTAC 274
LTE + V E + EV +R C L VL+A L KD SD +V +
Sbjct: 107 LTEVDPDEEVQGEIHLRLEVWPGARACRLRCSVLEARDLAPKDRNGTSDPFVRVRYK--- 163
Query: 275 SHRLQTRTVKNSSSPVWNQSFHFRIHRQLKNVMELKVFDQDLVTGDDPVLSVLFDAGTLR 334
+T VK S P WN++F F + + ++ +D DLV+ +D + V+ D LR
Sbjct: 164 GRTRETSIVKKSCYPRWNETFEFELQEGAMEALCVEAWDWDLVSRNDFLGKVVIDVQRLR 223
Query: 335 AGEFRRESFSLSP-QGEGRLEVEFRLQSL 362
+ F L P Q + R E L SL
Sbjct: 224 VVQQEEGWFRLQPDQSKSRRHDEGNLGSL 252
Score = 37.0 bits (84), Expect = 0.094
Identities = 33/146 (22%), Positives = 63/146 (43%), Gaps = 13/146 (8%)
Query: 243 LTVRVLQAHRLPSKDLVTPSDCYVTLWLPTACSHRLQTRTVKNSSSPVWNQSFHFRIHRQ 302
L +R+++ LP+KD+ SD Y + + ++T TV + P W + + +
Sbjct: 7 LYIRIVEGKNLPAKDITGSSDPYCIVKVDN--EPIIRTATVWKTLCPFWGEEYQVHLPPT 64
Query: 303 LKNVMELKVFDQDLVTGDDPVLSVLFDAGTLRAGEFRRESFS-------LSPQGEGRLEV 355
+ + V D+D ++ DD + V T+ + + FS + P E + E+
Sbjct: 65 F-HAVAFYVMDEDALSRDDVIGKVCLTRDTIAS---HPKGFSGWAHLTEVDPDEEVQGEI 120
Query: 356 EFRLQSLADRGEWLVSNGVLVARELS 381
RL+ + VL AR+L+
Sbjct: 121 HLRLEVWPGARACRLRCSVLEARDLA 146
>gi|239508992 PREDICTED: similar to calcium-promoted Ras inactivator
isoform 1 [Homo sapiens]
Length = 731
Score = 52.0 bits (123), Expect = 3e-06
Identities = 46/149 (30%), Positives = 66/149 (44%), Gaps = 7/149 (4%)
Query: 218 LTEEGTFKVVDEEAMEKAEV---SRTCLLTVRVLQAHRLPSKDLVTPSDCYVTLWLPTAC 274
LTE + V E + EV +R C L VL+A L KD SD +V +
Sbjct: 35 LTEVDPDEEVQGEIHLRLEVWPGARACRLRCSVLEARDLAPKDRNGTSDPFVRVRYK--- 91
Query: 275 SHRLQTRTVKNSSSPVWNQSFHFRIHRQLKNVMELKVFDQDLVTGDDPVLSVLFDAGTLR 334
+T VK S P WN++F F + + ++ +D DLV+ +D + V+ D LR
Sbjct: 92 GRTRETSIVKKSCYPRWNETFEFELQEGAMEALCVEAWDWDLVSRNDFLGKVVIDVQRLR 151
Query: 335 AGEFRRESFSLSP-QGEGRLEVEFRLQSL 362
+ F L P Q + R E L SL
Sbjct: 152 VVQQEEGWFRLQPDQSKSRRHDEGNLGSL 180
>gi|239508990 PREDICTED: similar to calcium-promoted Ras inactivator
isoform 2 [Homo sapiens]
Length = 757
Score = 52.0 bits (123), Expect = 3e-06
Identities = 46/149 (30%), Positives = 66/149 (44%), Gaps = 7/149 (4%)
Query: 218 LTEEGTFKVVDEEAMEKAEV---SRTCLLTVRVLQAHRLPSKDLVTPSDCYVTLWLPTAC 274
LTE + V E + EV +R C L VL+A L KD SD +V +
Sbjct: 107 LTEVDPDEEVQGEIHLRLEVWPGARACRLRCSVLEARDLAPKDRNGTSDPFVRVRYK--- 163
Query: 275 SHRLQTRTVKNSSSPVWNQSFHFRIHRQLKNVMELKVFDQDLVTGDDPVLSVLFDAGTLR 334
+T VK S P WN++F F + + ++ +D DLV+ +D + V+ D LR
Sbjct: 164 GRTRETSIVKKSCYPRWNETFEFELQEGAMEALCVEAWDWDLVSRNDFLGKVVIDVQRLR 223
Query: 335 AGEFRRESFSLSP-QGEGRLEVEFRLQSL 362
+ F L P Q + R E L SL
Sbjct: 224 VVQQEEGWFRLQPDQSKSRRHDEGNLGSL 252
Score = 37.0 bits (84), Expect = 0.094
Identities = 33/146 (22%), Positives = 63/146 (43%), Gaps = 13/146 (8%)
Query: 243 LTVRVLQAHRLPSKDLVTPSDCYVTLWLPTACSHRLQTRTVKNSSSPVWNQSFHFRIHRQ 302
L +R+++ LP+KD+ SD Y + + ++T TV + P W + + +
Sbjct: 7 LYIRIVEGKNLPAKDITGSSDPYCIVKVDN--EPIIRTATVWKTLCPFWGEEYQVHLPPT 64
Query: 303 LKNVMELKVFDQDLVTGDDPVLSVLFDAGTLRAGEFRRESFS-------LSPQGEGRLEV 355
+ + V D+D ++ DD + V T+ + + FS + P E + E+
Sbjct: 65 F-HAVAFYVMDEDALSRDDVIGKVCLTRDTIAS---HPKGFSGWAHLTEVDPDEEVQGEI 120
Query: 356 EFRLQSLADRGEWLVSNGVLVARELS 381
RL+ + VL AR+L+
Sbjct: 121 HLRLEVWPGARACRLRCSVLEARDLA 146
>gi|121114292 RAS p21 protein activator 4 isoform 2 [Homo sapiens]
Length = 757
Score = 52.0 bits (123), Expect = 3e-06
Identities = 46/149 (30%), Positives = 66/149 (44%), Gaps = 7/149 (4%)
Query: 218 LTEEGTFKVVDEEAMEKAEV---SRTCLLTVRVLQAHRLPSKDLVTPSDCYVTLWLPTAC 274
LTE + V E + EV +R C L VL+A L KD SD +V +
Sbjct: 107 LTEVDPDEEVQGEIHLRLEVWPGARACRLRCSVLEARDLAPKDRNGTSDPFVRVRYK--- 163
Query: 275 SHRLQTRTVKNSSSPVWNQSFHFRIHRQLKNVMELKVFDQDLVTGDDPVLSVLFDAGTLR 334
+T VK S P WN++F F + + ++ +D DLV+ +D + V+ D LR
Sbjct: 164 GRTRETSIVKKSCYPRWNETFEFELQEGAMEALCVEAWDWDLVSRNDFLGKVVIDVQRLR 223
Query: 335 AGEFRRESFSLSP-QGEGRLEVEFRLQSL 362
+ F L P Q + R E L SL
Sbjct: 224 VVQQEEGWFRLQPDQSKSRRHDEGNLGSL 252
Score = 37.0 bits (84), Expect = 0.094
Identities = 33/146 (22%), Positives = 63/146 (43%), Gaps = 13/146 (8%)
Query: 243 LTVRVLQAHRLPSKDLVTPSDCYVTLWLPTACSHRLQTRTVKNSSSPVWNQSFHFRIHRQ 302
L +R+++ LP+KD+ SD Y + + ++T TV + P W + + +
Sbjct: 7 LYIRIVEGKNLPAKDITGSSDPYCIVKVDN--EPIIRTATVWKTLCPFWGEEYQVHLPPT 64
Query: 303 LKNVMELKVFDQDLVTGDDPVLSVLFDAGTLRAGEFRRESFS-------LSPQGEGRLEV 355
+ + V D+D ++ DD + V T+ + + FS + P E + E+
Sbjct: 65 F-HAVAFYVMDEDALSRDDVIGKVCLTRDTIAS---HPKGFSGWAHLTEVDPDEEVQGEI 120
Query: 356 EFRLQSLADRGEWLVSNGVLVARELS 381
RL+ + VL AR+L+
Sbjct: 121 HLRLEVWPGARACRLRCSVLEARDLA 146
>gi|121114294 RAS p21 protein activator 4 isoform 1 [Homo sapiens]
Length = 803
Score = 52.0 bits (123), Expect = 3e-06
Identities = 46/149 (30%), Positives = 66/149 (44%), Gaps = 7/149 (4%)
Query: 218 LTEEGTFKVVDEEAMEKAEV---SRTCLLTVRVLQAHRLPSKDLVTPSDCYVTLWLPTAC 274
LTE + V E + EV +R C L VL+A L KD SD +V +
Sbjct: 107 LTEVDPDEEVQGEIHLRLEVWPGARACRLRCSVLEARDLAPKDRNGTSDPFVRVRYK--- 163
Query: 275 SHRLQTRTVKNSSSPVWNQSFHFRIHRQLKNVMELKVFDQDLVTGDDPVLSVLFDAGTLR 334
+T VK S P WN++F F + + ++ +D DLV+ +D + V+ D LR
Sbjct: 164 GRTRETSIVKKSCYPRWNETFEFELQEGAMEALCVEAWDWDLVSRNDFLGKVVIDVQRLR 223
Query: 335 AGEFRRESFSLSP-QGEGRLEVEFRLQSL 362
+ F L P Q + R E L SL
Sbjct: 224 VVQQEEGWFRLQPDQSKSRRHDEGNLGSL 252
Score = 37.0 bits (84), Expect = 0.094
Identities = 33/146 (22%), Positives = 63/146 (43%), Gaps = 13/146 (8%)
Query: 243 LTVRVLQAHRLPSKDLVTPSDCYVTLWLPTACSHRLQTRTVKNSSSPVWNQSFHFRIHRQ 302
L +R+++ LP+KD+ SD Y + + ++T TV + P W + + +
Sbjct: 7 LYIRIVEGKNLPAKDITGSSDPYCIVKVDN--EPIIRTATVWKTLCPFWGEEYQVHLPPT 64
Query: 303 LKNVMELKVFDQDLVTGDDPVLSVLFDAGTLRAGEFRRESFS-------LSPQGEGRLEV 355
+ + V D+D ++ DD + V T+ + + FS + P E + E+
Sbjct: 65 F-HAVAFYVMDEDALSRDDVIGKVCLTRDTIAS---HPKGFSGWAHLTEVDPDEEVQGEI 120
Query: 356 EFRLQSLADRGEWLVSNGVLVARELS 381
RL+ + VL AR+L+
Sbjct: 121 HLRLEVWPGARACRLRCSVLEARDLA 146
>gi|122937247 unc-13 homolog A [Homo sapiens]
Length = 1791
Score = 50.4 bits (119), Expect = 8e-06
Identities = 38/159 (23%), Positives = 76/159 (47%), Gaps = 18/159 (11%)
Query: 243 LTVRVLQAHRLPSKDLVTPSDCYVTLWLPTACSHRLQTRTVKNSSSPVWNQSFHFRIHRQ 302
+++ V+ A L +KD SD YVT+ + + +T+T+ + +PVW ++FHF H
Sbjct: 766 ISITVVCAQGLQAKDKTGSSDPYVTVQVGKT---KKRTKTIYGNLNPVWEENFHFECHNS 822
Query: 303 LKNVMELKVFDQDLVTGDDPVLSVLFDAGTLRAGEFRRESFSLSPQGEGRLEVEFRLQSL 362
+ +++V+D+ DD + S + + +F ++ G ++V + L
Sbjct: 823 SDRI-KVRVWDE-----DDDIKSRVKQRFKRESDDFLGQTIIEVRTLSGEMDVWYNLDKR 876
Query: 363 ADRGEWLVSNGVLVARELSCLHVQLEETGDQKSSEHRVQ 401
D+ VS + LH+ +E G++K + + VQ
Sbjct: 877 TDKS--AVSGAIR-------LHISVEIKGEEKVAPYHVQ 906
>gi|110611226 UNC13 (C. elegans)-like [Homo sapiens]
Length = 1591
Score = 48.9 bits (115), Expect = 2e-05
Identities = 38/159 (23%), Positives = 75/159 (47%), Gaps = 18/159 (11%)
Query: 243 LTVRVLQAHRLPSKDLVTPSDCYVTLWLPTACSHRLQTRTVKNSSSPVWNQSFHFRIHRQ 302
+T+ V+ A L +KD SD YVT+ + + +T+T+ + +PVW + FHF H
Sbjct: 602 ITITVVCAQGLQAKDKTGSSDPYVTVQVSKT---KKRTKTIFGNLNPVWEEKFHFECHNS 658
Query: 303 LKNVMELKVFDQDLVTGDDPVLSVLFDAGTLRAGEFRRESFSLSPQGEGRLEVEFRLQSL 362
+ +++V+D+ DD + S + + +F ++ G ++V + L+
Sbjct: 659 SDRI-KVRVWDE-----DDDIKSRVKQRLKRESDDFLGQTIIEVRTLSGEMDVWYNLEKR 712
Query: 363 ADRGEWLVSNGVLVARELSCLHVQLEETGDQKSSEHRVQ 401
D+ VS + L + +E G++K + + VQ
Sbjct: 713 TDKS--AVSGAIR-------LQISVEIKGEEKVAPYHVQ 742
>gi|122937514 unc-13 homolog C [Homo sapiens]
Length = 2214
Score = 48.5 bits (114), Expect = 3e-05
Identities = 41/199 (20%), Positives = 94/199 (47%), Gaps = 29/199 (14%)
Query: 213 PATYQLTEEGTFKVVDEEAMEKAEVSRTCLL----------TVRVLQAHRLPSKDLVTPS 262
P +++ +E F++ E+ ++ + ++ +L T+ V+ A L +KD S
Sbjct: 1183 PEVFEVIQE-MFQISKEDFVQFTKAAKQSVLDGTSKWSAKITITVVSAQGLQAKDKTGSS 1241
Query: 263 DCYVTLWLPTACSHRLQTRTVKNSSSPVWNQSFHFRIHRQLKNVMELKVFDQDLVTGDDP 322
D YVT+ + ++ +T+T+ + +PVW++ F+F H + +++V+D+ DD
Sbjct: 1242 DPYVTVQVG---KNKRRTKTIFGNLNPVWDEKFYFECHNSTDRI-KVRVWDE-----DDD 1292
Query: 323 VLSVLFDAGTLRAGEFRRESFSLSPQGEGRLEVEFRLQSLADRGEWLVSNGVLVARELSC 382
+ S + + +F ++ G ++V + L+ D+ VS +
Sbjct: 1293 IKSRVKQHFKKESDDFLGQTIVEVRTLSGEMDVWYNLEKRTDKS--AVSGAIR------- 1343
Query: 383 LHVQLEETGDQKSSEHRVQ 401
L + +E G++K + + +Q
Sbjct: 1344 LKINVEIKGEEKVAPYHIQ 1362
>gi|39752671 synaptotagmin X [Homo sapiens]
Length = 523
Score = 48.1 bits (113), Expect = 4e-05
Identities = 28/90 (31%), Positives = 51/90 (56%), Gaps = 2/90 (2%)
Query: 242 LLTVRVLQAHRLPSKDLVTPSDCYVTLWLPTACSHRLQTRTVKNSSSPVWNQSFHFRI-H 300
LL V++++A LP+KD SD YV ++L + QTR + + +P+++++F F + +
Sbjct: 247 LLVVKIIKALDLPAKDFTGTSDPYVKMYLLPDRKKKFQTRVHRKTLNPLFDETFQFPVAY 306
Query: 301 RQLKN-VMELKVFDQDLVTGDDPVLSVLFD 329
QL N + V+D D + D + V+ D
Sbjct: 307 DQLSNRKLHFSVYDFDRFSRHDMIGEVILD 336
Score = 32.3 bits (72), Expect = 2.3
Identities = 28/90 (31%), Positives = 46/90 (51%), Gaps = 9/90 (10%)
Query: 243 LTVRVLQAHRLPSKDLVTPSDCYVTLWLPTACSHRL----QTRTVKNSSSPVWNQSFHFR 298
+T+ V++ L + D+ SD YV + L C R +T T KN+ +PV+N++ F
Sbjct: 380 MTLTVIKCRNLKAMDITGSSDPYVKVSL--MCEGRRLKKRKTTTKKNTLNPVYNEAIIFD 437
Query: 299 IHRQLKNVMELK--VFDQDLVTGDDPVLSV 326
I + + + L V D D V G + V+ V
Sbjct: 438 IPPENVDQVSLSIAVMDYDRV-GHNEVIGV 466
>gi|227496489 multiple C2 domains, transmembrane 2 isoform 2 [Homo
sapiens]
Length = 823
Score = 47.0 bits (110), Expect = 9e-05
Identities = 33/87 (37%), Positives = 49/87 (56%), Gaps = 7/87 (8%)
Query: 236 EVSRTCLLTVRVLQAHRLPSKDLVTPSDCYVTLWLPTACSHRLQTRTVKNSSSPVWNQSF 295
+V +L V+VL+A L + D SD + L L + RLQT TV + +P WN+ F
Sbjct: 504 DVKDVGILQVKVLKAADLLAADFSGKSDPFCLLELG---NDRLQTHTVYKNLNPEWNKVF 560
Query: 296 HFRIHRQLKNVMELKVFDQDLVTGDDP 322
F I + + +V+E+ VFD+D GD P
Sbjct: 561 TFPI-KDIHDVLEVTVFDED---GDKP 583
Score = 34.7 bits (78), Expect = 0.47
Identities = 22/79 (27%), Positives = 40/79 (50%), Gaps = 3/79 (3%)
Query: 242 LLTVRVLQAHRLPSKDLVTPSDCYVTLWLPTACSHRLQTRTVKNSSSPVWNQSFHFRIHR 301
LLT+ + + L +D SD YV L ++ ++ + + +PVW++ I +
Sbjct: 195 LLTIHLKEGRNLVVRDRCGTSDPYVKFKLNGKTLYK--SKVIYKNLNPVWDEIVVLPI-Q 251
Query: 302 QLKNVMELKVFDQDLVTGD 320
L + +KV+D+DL T D
Sbjct: 252 SLDQKLRVKVYDRDLTTSD 270
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.135 0.421
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 42,825,740
Number of Sequences: 37866
Number of extensions: 2123553
Number of successful extensions: 5317
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 45
Number of HSP's successfully gapped in prelim test: 65
Number of HSP's that attempted gapping in prelim test: 5156
Number of HSP's gapped (non-prelim): 196
length of query: 1012
length of database: 18,247,518
effective HSP length: 112
effective length of query: 900
effective length of database: 14,006,526
effective search space: 12605873400
effective search space used: 12605873400
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.