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Search of human proteins with 13376146
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|13376146 zinc finger and BTB domain containing 3 [Homo
sapiens]
(574 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|13376146 zinc finger and BTB domain containing 3 [Homo sapiens] 1177 0.0
gi|45439302 zinc finger protein 238 isoform 1 [Homo sapiens] 269 5e-72
gi|19923354 zinc finger protein 238 isoform 2 [Homo sapiens] 269 6e-72
gi|212286156 zinc finger and BTB domain containing 42 [Homo sapi... 220 3e-57
gi|7705375 zinc finger and BTB domain containing 7A [Homo sapiens] 118 1e-26
gi|7662074 zinc finger and BTB domain containing 5 [Homo sapiens] 117 3e-26
gi|167234429 zinc finger and BTB domain containing 17 [Homo sapi... 112 9e-25
gi|148237270 hypermethylated in cancer 1 isoform 2 [Homo sapiens] 112 1e-24
gi|61676186 hypermethylated in cancer 1 isoform 1 [Homo sapiens] 112 1e-24
gi|139394599 hypermethylated in cancer 2 [Homo sapiens] 107 4e-23
gi|47679080 zinc finger and BTB domain containing 46 [Homo sapiens] 105 1e-22
gi|32469511 B-cell CLL/lymphoma 6, member B (zinc finger protein... 102 1e-21
gi|109134351 zinc finger and BTB domain containing 44 [Homo sapi... 100 6e-21
gi|223972645 zinc finger protein 509 [Homo sapiens] 96 9e-20
gi|94721342 zinc finger and BTB domain containing 8A [Homo sapiens] 94 4e-19
gi|224591419 zinc finger and BTB domain containing 8B [Homo sapi... 88 2e-17
gi|23308693 zinc finger and BTB domain containing 9 [Homo sapiens] 88 2e-17
gi|197927147 B-cell lymphoma 6 protein isoform 2 [Homo sapiens] 87 4e-17
gi|8923885 myoneurin [Homo sapiens] 87 4e-17
gi|84872173 zinc finger protein 131 [Homo sapiens] 86 9e-17
gi|21040324 B-cell lymphoma 6 protein isoform 1 [Homo sapiens] 82 1e-15
gi|195927002 B-cell lymphoma 6 protein isoform 1 [Homo sapiens] 82 1e-15
gi|223890203 zinc finger and BTB domain containing 22 [Homo sapi... 81 2e-15
gi|223890199 zinc finger and BTB domain containing 22 [Homo sapi... 81 2e-15
gi|139394579 zinc finger and BTB domain containing 40 [Homo sapi... 81 2e-15
gi|139394556 zinc finger and BTB domain containing 40 [Homo sapi... 81 2e-15
gi|182509180 zinc finger and BTB domain containing 1 isoform 1 [... 80 5e-15
gi|182509178 zinc finger and BTB domain containing 1 isoform 2 [... 80 5e-15
gi|23397572 kelch-like 34 [Homo sapiens] 79 1e-14
gi|157694497 zinc finger and BTB domain containing 10 isoform b ... 77 6e-14
>gi|13376146 zinc finger and BTB domain containing 3 [Homo sapiens]
Length = 574
Score = 1177 bits (3045), Expect = 0.0
Identities = 574/574 (100%), Positives = 574/574 (100%)
Query: 1 MLREFSKWGVEASPGKAWERKRSLLRGAVGRYRGATGGDLFWAPFPSWGTMEFPEHSQQL 60
MLREFSKWGVEASPGKAWERKRSLLRGAVGRYRGATGGDLFWAPFPSWGTMEFPEHSQQL
Sbjct: 1 MLREFSKWGVEASPGKAWERKRSLLRGAVGRYRGATGGDLFWAPFPSWGTMEFPEHSQQL 60
Query: 61 LQSLREQRSQGFLCDCTVMVGSTQFLAHRAVLASCSPFFQLFYKERELDKRDLVCIHNEI 120
LQSLREQRSQGFLCDCTVMVGSTQFLAHRAVLASCSPFFQLFYKERELDKRDLVCIHNEI
Sbjct: 61 LQSLREQRSQGFLCDCTVMVGSTQFLAHRAVLASCSPFFQLFYKERELDKRDLVCIHNEI 120
Query: 121 VTAPAFGLLLDFMYAGQLTLRGDTPVEDVLAAASYLHMNDIVKVCKRRLQARALAEADST 180
VTAPAFGLLLDFMYAGQLTLRGDTPVEDVLAAASYLHMNDIVKVCKRRLQARALAEADST
Sbjct: 121 VTAPAFGLLLDFMYAGQLTLRGDTPVEDVLAAASYLHMNDIVKVCKRRLQARALAEADST 180
Query: 181 KKEEETNSQLPSLEFLSSTSRGTQPSLASAETSGHWGKGEWKGSAAPSPTVRPPDEPPMS 240
KKEEETNSQLPSLEFLSSTSRGTQPSLASAETSGHWGKGEWKGSAAPSPTVRPPDEPPMS
Sbjct: 181 KKEEETNSQLPSLEFLSSTSRGTQPSLASAETSGHWGKGEWKGSAAPSPTVRPPDEPPMS 240
Query: 241 SGADTTQPGMEVDAPHLRAPHPPVADVSLASPSSSTETIPTNYFSSGISAVSLEPLPSLD 300
SGADTTQPGMEVDAPHLRAPHPPVADVSLASPSSSTETIPTNYFSSGISAVSLEPLPSLD
Sbjct: 241 SGADTTQPGMEVDAPHLRAPHPPVADVSLASPSSSTETIPTNYFSSGISAVSLEPLPSLD 300
Query: 301 VGPESLRVVEPKDPGGPLQGFYPPASAPTSAPAPVSAPVPSQAPAPAEAELVQVKVEAIV 360
VGPESLRVVEPKDPGGPLQGFYPPASAPTSAPAPVSAPVPSQAPAPAEAELVQVKVEAIV
Sbjct: 301 VGPESLRVVEPKDPGGPLQGFYPPASAPTSAPAPVSAPVPSQAPAPAEAELVQVKVEAIV 360
Query: 361 ISDEETDVSDEQPQGPERAFPSGGAVYGAQPSQPEAFEDPGAAGLEEVGPSDHFLPTDPH 420
ISDEETDVSDEQPQGPERAFPSGGAVYGAQPSQPEAFEDPGAAGLEEVGPSDHFLPTDPH
Sbjct: 361 ISDEETDVSDEQPQGPERAFPSGGAVYGAQPSQPEAFEDPGAAGLEEVGPSDHFLPTDPH 420
Query: 421 LPYHLLPGAGQYHRGLVTSPLPAPASLHEPLYLSSEYEAAPGSFGVFTEDVPTCKTCGKT 480
LPYHLLPGAGQYHRGLVTSPLPAPASLHEPLYLSSEYEAAPGSFGVFTEDVPTCKTCGKT
Sbjct: 421 LPYHLLPGAGQYHRGLVTSPLPAPASLHEPLYLSSEYEAAPGSFGVFTEDVPTCKTCGKT 480
Query: 481 FSCSYTLRRHATVHTRERPYECRYCLRSYTQSGDLYRHIRKAHNEDLAKRSKPDPEVGPL 540
FSCSYTLRRHATVHTRERPYECRYCLRSYTQSGDLYRHIRKAHNEDLAKRSKPDPEVGPL
Sbjct: 481 FSCSYTLRRHATVHTRERPYECRYCLRSYTQSGDLYRHIRKAHNEDLAKRSKPDPEVGPL 540
Query: 541 LGVQPLPGSPTADRQSSSGGGPPKDFVLAPKTNI 574
LGVQPLPGSPTADRQSSSGGGPPKDFVLAPKTNI
Sbjct: 541 LGVQPLPGSPTADRQSSSGGGPPKDFVLAPKTNI 574
>gi|45439302 zinc finger protein 238 isoform 1 [Homo sapiens]
Length = 531
Score = 269 bits (688), Expect = 5e-72
Identities = 205/531 (38%), Positives = 265/531 (49%), Gaps = 94/531 (17%)
Query: 50 TMEFPEHSQQLLQSLREQRSQGFLCDCTVMVGSTQFLAHRAVLASCSPFFQLFYKERELD 109
+MEFP+HS+ LLQ L EQR QGFLCDCTV+VG QF AHRAVLASCS +F LFYK+ +LD
Sbjct: 9 SMEFPDHSRHLLQCLSEQRHQGFLCDCTVLVGDAQFRAHRAVLASCSMYFHLFYKD-QLD 67
Query: 110 KRDLVCIHNEIVTAPAFGLLLDFMYAGQLTLRGDTPVEDVLAAASYLHMNDIVKVCKRRL 169
KRD+V ++++IVTAPAF LLL+FMY G+L + D P+EDVLAAASYLHM DIVKVCK++L
Sbjct: 68 KRDIVHLNSDIVTAPAFALLLEFMYEGKLQFK-DLPIEDVLAAASYLHMYDIVKVCKKKL 126
Query: 170 QARALAEADSTKKEEETNSQLPSLEFLSSTSRGTQPSLASAETSGHWGKGEWKGSAAPSP 229
+ +A EADSTKKEE+ +S +E LS S L S E G + K + PS
Sbjct: 127 KEKATTEADSTKKEEDASSCSDKVESLSDGSSHIAGDLPSDEDEGE----DEKLNILPSK 182
Query: 230 TVRPPDEPPM-----SSGADTTQPGMEVDAPHLRAPHPPVADVSLASPSSSTETIPTNYF 284
+ M S A Q G E + PH A ++ASP SSTE++
Sbjct: 183 RDLAAEPGNMWMRLPSDSAGIPQAGGEAE------PHATAAGKTVASPCSSTESLSQRSV 236
Query: 285 SSGISAVSLEPLPSLDVGPESLRVVEPKDPGGPLQGFYPPASAPTSAPAPVSAPVPSQAP 344
+S + ++ + L V SL VE + S+ SQ
Sbjct: 237 TSVRDSADVDCVLDLSV-KSSLSGVENLN----------------------SSYFSSQ-- 271
Query: 345 APAEAELVQVKVEAIVISDEE----TDVSDEQPQGPERAFPSGGAVYGAQPSQP------ 394
+ LVQVKVE DE D E E + Y P
Sbjct: 272 DVLRSNLVQVKVEKEASCDESDVGTNDYDMEHSTVKESVSTNNRVQYEPAHLAPLREDSV 331
Query: 395 --EAFEDPGAAGLEEVGPSDHFLPTD-----PHLPY--HLLPGAGQ-YHRGLVTSPLPAP 444
E + A+ E + P + + LPY ++L AGQ + L P+P
Sbjct: 332 LRELDREDKASDDEMMTPESERVQVEGGMESSLLPYVSNILSPAGQIFMCPLCNKVFPSP 391
Query: 445 ASLHEPLYLSSEYEAAPG--SFGVFTEDVPTCKTCGKTFSCSYTLR-------------- 488
L ++LS+ + G S +VPTC CGKTFSC YTL+
Sbjct: 392 HILQ--IHLSTHFREQDGIRSKPAADVNVPTCSLCGKTFSCMYTLKRHERTHSGEKPYTC 449
Query: 489 --------------RHATVHTRERPYECRYCLRSYTQSGDLYRHIRKAHNE 525
RHA VHTRE+P+ C++C R +TQSGDLYRHIRK H E
Sbjct: 450 TQCGKSFQYSHNLSRHAVVHTREKPHACKWCERRFTQSGDLYRHIRKFHCE 500
>gi|19923354 zinc finger protein 238 isoform 2 [Homo sapiens]
Length = 522
Score = 269 bits (687), Expect = 6e-72
Identities = 205/530 (38%), Positives = 264/530 (49%), Gaps = 94/530 (17%)
Query: 51 MEFPEHSQQLLQSLREQRSQGFLCDCTVMVGSTQFLAHRAVLASCSPFFQLFYKERELDK 110
MEFP+HS+ LLQ L EQR QGFLCDCTV+VG QF AHRAVLASCS +F LFYK+ +LDK
Sbjct: 1 MEFPDHSRHLLQCLSEQRHQGFLCDCTVLVGDAQFRAHRAVLASCSMYFHLFYKD-QLDK 59
Query: 111 RDLVCIHNEIVTAPAFGLLLDFMYAGQLTLRGDTPVEDVLAAASYLHMNDIVKVCKRRLQ 170
RD+V ++++IVTAPAF LLL+FMY G+L + D P+EDVLAAASYLHM DIVKVCK++L+
Sbjct: 60 RDIVHLNSDIVTAPAFALLLEFMYEGKLQFK-DLPIEDVLAAASYLHMYDIVKVCKKKLK 118
Query: 171 ARALAEADSTKKEEETNSQLPSLEFLSSTSRGTQPSLASAETSGHWGKGEWKGSAAPSPT 230
+A EADSTKKEE+ +S +E LS S L S E G + K + PS
Sbjct: 119 EKATTEADSTKKEEDASSCSDKVESLSDGSSHIAGDLPSDEDEGE----DEKLNILPSKR 174
Query: 231 VRPPDEPPM-----SSGADTTQPGMEVDAPHLRAPHPPVADVSLASPSSSTETIPTNYFS 285
+ M S A Q G E + PH A ++ASP SSTE++ +
Sbjct: 175 DLAAEPGNMWMRLPSDSAGIPQAGGEAE------PHATAAGKTVASPCSSTESLSQRSVT 228
Query: 286 SGISAVSLEPLPSLDVGPESLRVVEPKDPGGPLQGFYPPASAPTSAPAPVSAPVPSQAPA 345
S + ++ + L V SL VE + S+ SQ
Sbjct: 229 SVRDSADVDCVLDLSV-KSSLSGVENLN----------------------SSYFSSQ--D 263
Query: 346 PAEAELVQVKVEAIVISDEE----TDVSDEQPQGPERAFPSGGAVYGAQPSQP------- 394
+ LVQVKVE DE D E E + Y P
Sbjct: 264 VLRSNLVQVKVEKEASCDESDVGTNDYDMEHSTVKESVSTNNRVQYEPAHLAPLREDSVL 323
Query: 395 -EAFEDPGAAGLEEVGPSDHFLPTD-----PHLPY--HLLPGAGQ-YHRGLVTSPLPAPA 445
E + A+ E + P + + LPY ++L AGQ + L P+P
Sbjct: 324 RELDREDKASDDEMMTPESERVQVEGGMESSLLPYVSNILSPAGQIFMCPLCNKVFPSPH 383
Query: 446 SLHEPLYLSSEYEAAPG--SFGVFTEDVPTCKTCGKTFSCSYTLR--------------- 488
L ++LS+ + G S +VPTC CGKTFSC YTL+
Sbjct: 384 ILQ--IHLSTHFREQDGIRSKPAADVNVPTCSLCGKTFSCMYTLKRHERTHSGEKPYTCT 441
Query: 489 -------------RHATVHTRERPYECRYCLRSYTQSGDLYRHIRKAHNE 525
RHA VHTRE+P+ C++C R +TQSGDLYRHIRK H E
Sbjct: 442 QCGKSFQYSHNLSRHAVVHTREKPHACKWCERRFTQSGDLYRHIRKFHCE 491
>gi|212286156 zinc finger and BTB domain containing 42 [Homo
sapiens]
Length = 422
Score = 220 bits (560), Expect = 3e-57
Identities = 179/510 (35%), Positives = 224/510 (43%), Gaps = 134/510 (26%)
Query: 51 MEFPEHSQQLLQSLREQRSQGFLCDCTVMVGSTQFLAHRAVLASCSPFFQLFYKERELDK 110
MEFPEH +LL LR+QR GFLCDCTV+VG +F AHRAVLA+CS +F LFY++R
Sbjct: 1 MEFPEHGGRLLGRLRQQRELGFLCDCTVLVGDARFPAHRAVLAACSVYFHLFYRDRPAGS 60
Query: 111 RDLVCIHNEIVTAPAFGLLLDFMYAGQLTLRGDTPVEDVLAAASYLHMNDIVKVCKRRLQ 170
RD V ++ +IVTAPAFG LLDFMY G+L LR PVEDVLAAASYLHM DIVKVCK RLQ
Sbjct: 61 RDTVRLNGDIVTAPAFGRLLDFMYEGRLDLR-SLPVEDVLAAASYLHMYDIVKVCKGRLQ 119
Query: 171 ARALAEADSTKKEEETNSQLPSLEFLSSTSRGTQPSLASAETSGHWGKGEWKGSAAPSPT 230
+K+ + P+ P A+ W W +A P
Sbjct: 120 ----------EKDRSLDPGNPA------------PGAEPAQPPCPW--PVW--TADLCPA 153
Query: 231 VRPPDEPPMSSGADTTQPGMEVDAPHLRAPHPPVADVSLASPSSSTETIPTNYFSSGISA 290
R PP G++ P RA PP V P S + +
Sbjct: 154 ARKAKLPPF---------GVKAALPP-RASGPPPCQV----PEESDQALDL--------- 190
Query: 291 VSLEPLPSLDVGPESLRVVEPKDPGGPLQGFYPPASAPTSAPAPVSAPVPSQAPAPAEAE 350
SL GP RV +PP T P+ SQ A+
Sbjct: 191 -------SLKSGPRQERV-------------HPPCVLQT--------PLCSQRQPGAQP- 221
Query: 351 LVQVKVEAIVISDEETDVSDEQPQGPERAFPSGGAVYGAQPSQPEAFEDPGAAGLE---- 406
VK E +S++E S P P + P A QP G+ LE
Sbjct: 222 --LVKDERDSLSEQEESSSSRSPHSPPKPPPVPAAKGLVVGLQPLPLSGEGSRELELGAG 279
Query: 407 EVGPSDHFLPTDPHLPYHLLPGAGQYHRGLVTSPLPA---PASLHEPLYLSSEYEAAPGS 463
+ D P P L PL + P+S L+LS+ + +
Sbjct: 280 RLASEDELGPGGP----------------LCICPLCSKLFPSSHVLQLHLSAHFRERDST 323
Query: 464 FGVFTED--VPTCKTCGKTFSCSYTLR----------------------------RHATV 493
+ D PTC CGKTFSC+YTL+ RH V
Sbjct: 324 RARLSPDGVAPTCPLCGKTFSCTYTLKRHERTHSGEKPYTCVQCGKSFQYSHNLSRHTVV 383
Query: 494 HTRERPYECRYCLRSYTQSGDLYRHIRKAH 523
HTRE+P+ CR+C R +TQSGDLYRH+RK H
Sbjct: 384 HTREKPHACRWCERRFTQSGDLYRHVRKFH 413
>gi|7705375 zinc finger and BTB domain containing 7A [Homo sapiens]
Length = 584
Score = 118 bits (296), Expect = 1e-26
Identities = 131/540 (24%), Positives = 207/540 (38%), Gaps = 73/540 (13%)
Query: 53 FPEHSQQLLQSLREQRSQGFLCDCTVMVGSTQFLAHRAVLASCSPFF-QLFYKERELDKR 111
FP+HS +L L EQR+QG LCD ++V +F HR+VLA+CS +F +LF +D++
Sbjct: 13 FPDHSSDILSGLNEQRTQGLLCDVVILVEGREFPTHRSVLAACSQYFKKLFTSGAVVDQQ 72
Query: 112 DLVCIHNEIVTAPAFGLLLDFMYAGQLTLRGDTPVEDVLAAASYLHMNDIVKVCKRRLQA 171
++ I + V+A A L+DF Y LT+ V D+L+AA L + + VC L
Sbjct: 73 NVYEI--DFVSAEALTALMDFAYTATLTV-STANVGDILSAARLLEIPAVSHVCADLLDR 129
Query: 172 RAL-AEADSTKKEEETNSQLPS---------LEFLSSTSRGTQPSLASAETSGHWGKGEW 221
+ L A+A + + + Q+ LEF S + P A+A + W
Sbjct: 130 QILAADAGADAGQLDLVDQIDQRNLLRAKEYLEFFQSNPMNSLPPAAAAAAASF----PW 185
Query: 222 KGSAAPSPTVRPPDEPPMSSGADTTQPGMEVDAPHLRAPHPPVADVSLASPSSSTETIPT 281
A + E ++ A + + P PP E PT
Sbjct: 186 SAFGASDDDLDATKEAVAAAVAAVA--AGDCNGLDFYGPGPP------------AERPPT 231
Query: 282 NYFSSGISAVSLEPLPSLDVGPESLRVVEPKDPGGPLQGFYPPASAPTSAPAPVSAPVPS 341
G S L P D L P G Y +A +AP P
Sbjct: 232 GDGDEGDSNPGLWPERDEDAPTGGLFPPPVAPPAATQNGHYGRGGEEEAASLSEAAPEPG 291
Query: 342 QAP----APAEAE--------------LVQVKVEAIVISDEETDVSDEQPQGPERA---- 379
+P AE E L+Q + ++ + SDE+ + ++
Sbjct: 292 DSPGFLSGAAEGEDGDGPDVDGLAASTLLQQMMSSVGRAGAAAGDSDEESRADDKGVMDY 351
Query: 380 ---FPSGGAVYGAQPSQPEAFEDPGAAGLEEVGPSDHFLPTDPHLPYHLLPGAGQYHRGL 436
+ SG P+ + E A + P + ++ GAG+ R +
Sbjct: 352 YLKYFSGAHDGDVYPAWSQKVEKKIRAKAFQKCP----------ICEKVIQGAGKLPRHI 401
Query: 437 VTSPLPAPASLHEPLYLSSEYEAAPGSFGVFTEDVP-TCKTCGKTFSCSYTLRRHATVHT 495
T P + + + T + P C+ CG F+ +Y L+ H VHT
Sbjct: 402 RTHTGEKPYECNICKVRFTRQDKLKVHMRKHTGEKPYLCQQCGAAFAHNYDLKNHMRVHT 461
Query: 496 RERPYECRYCLRSYTQSGDLYRHIRKAHNEDLAKRSKPDPEV-----GPLLGVQPLPGSP 550
RPY+C C +++ +S L+RH++K + R P V P G PG+P
Sbjct: 462 GLRPYQCDSCCKTFVRSDHLHRHLKKDGCNGVPSRRGRKPRVRGGAPDPSPGATATPGAP 521
>gi|7662074 zinc finger and BTB domain containing 5 [Homo sapiens]
Length = 677
Score = 117 bits (293), Expect = 3e-26
Identities = 59/141 (41%), Positives = 91/141 (64%), Gaps = 2/141 (1%)
Query: 51 MEFPEHSQQLLQSLREQRSQGFLCDCTVMVGSTQFLAHRAVLASCSPFFQLFYKERELDK 110
M+FP H +Q+ Q L QR G LCDC ++VG+ F AHR+VLA+CS F+ + E D+
Sbjct: 1 MDFPGHFEQIFQQLNYQRLHGQLCDCVIVVGNRHFKAHRSVLAACSTHFRALFSVAEGDQ 60
Query: 111 -RDLVCIHNEIVTAPAFGLLLDFMYAGQLTLRGDTPVEDVLAAASYLHMNDIVKVCKRRL 169
+++ + +E+VTA AF L+D MY L L G++ V DVL AAS+LH+N +VK CK L
Sbjct: 61 TMNMIQLDSEVVTAEAFAALIDMMYTSTLML-GESNVMDVLLAASHLHLNSVVKACKHYL 119
Query: 170 QARALAEADSTKKEEETNSQL 190
R L + +++ +E ++++
Sbjct: 120 TTRTLPMSPPSERVQEQSARM 140
Score = 48.9 bits (115), Expect = 1e-05
Identities = 20/45 (44%), Positives = 27/45 (60%)
Query: 474 CKTCGKTFSCSYTLRRHATVHTRERPYECRYCLRSYTQSGDLYRH 518
CK C KTF ++H VHT E+PY C C + ++QS LY+H
Sbjct: 615 CKICCKTFLTLTDCKKHIRVHTGEKPYACLKCGKRFSQSSHLYKH 659
>gi|167234429 zinc finger and BTB domain containing 17 [Homo
sapiens]
Length = 803
Score = 112 bits (280), Expect = 9e-25
Identities = 71/209 (33%), Positives = 104/209 (49%), Gaps = 20/209 (9%)
Query: 51 MEFPEHSQQLLQSLREQRSQGFLCDCTVMVGSTQFLAHRAVLASCSPFFQLFYKERELDK 110
M+FP+HSQ +L+ L +QR G LCDCT +V F AH+AVLA+CS +F++ + +D+
Sbjct: 1 MDFPQHSQHVLEQLNQQRQLGLLCDCTFVVDGVHFKAHKAVLAACSEYFKMLF----VDQ 56
Query: 111 RDLVCIHNEIVTAPAFGLLLDFMYAGQLTLRGDTPVEDVLAAASYLHMNDIVKVCKRRL- 169
+D+V H +I A G +L+FMY +L+L + V+DVLA A++L M DI+ C
Sbjct: 57 KDVV--HLDISNAAGLGQVLEFMYTAKLSLSPEN-VDDVLAVATFLQMQDIITACHALKS 113
Query: 170 ----------QARALAEADSTKKEEETNSQLPSLEFLSSTSRGTQ--PSLASAETSGHWG 217
A ALA K+ +E +L L R T PS E G
Sbjct: 114 LAEPATSPGGNAEALATEGGDKRAKEEKVATSTLSRLEQAGRSTPIGPSRDLKEERGGQA 173
Query: 218 KGEWKGSAAPSPTVRPPDEPPMSSGADTT 246
+ G+ P + PP+ D T
Sbjct: 174 QSAASGAEQTEKADAPREPPPVELKPDPT 202
Score = 55.5 bits (132), Expect = 1e-07
Identities = 21/47 (44%), Positives = 30/47 (63%)
Query: 474 CKTCGKTFSCSYTLRRHATVHTRERPYECRYCLRSYTQSGDLYRHIR 520
C+ CGK F+ S L+RH +H+ E+PY C +C R + G L RH+R
Sbjct: 476 CRECGKQFTTSGNLKRHLRIHSGEKPYVCIHCQRQFADPGALQRHVR 522
Score = 54.7 bits (130), Expect = 2e-07
Identities = 23/53 (43%), Positives = 34/53 (64%), Gaps = 1/53 (1%)
Query: 474 CKTCGKTFSCSYTLRRHATVHTRERPYECRYCLRSYTQSGDLYRHIRKAHNED 526
C+ CGK F+ S L+RH VH+ E+PY+C YC RS++ RH+ + H+ D
Sbjct: 392 CEDCGKLFTTSGNLKRHQLVHSGEKPYQCDYCGRSFSDPTSKMRHL-ETHDTD 443
Score = 48.9 bits (115), Expect = 1e-05
Identities = 51/217 (23%), Positives = 78/217 (35%), Gaps = 62/217 (28%)
Query: 325 ASAPTSAPAPVSAPVPSQAPAPAEAELV-------QVKVEAIVISDEETDVSDEQPQ--- 374
A AP P P P+ A AEAE +++VE +EE +EQ +
Sbjct: 186 ADAPREPPPVELKPDPTSGMAAAEAEAALSESSEQEMEVEPARKGEEEQKEQEEQEEEGA 245
Query: 375 GPERAFPSGGAVY-GAQPSQPEAFEDPGAAGLEEVGPSDHFLPTDPHLPYHLLPGAGQYH 433
GP G + G P + E E G +E+G
Sbjct: 246 GPAEVKEEGSQLENGEAPEENENEESAGTDSGQELGSEA--------------------- 284
Query: 434 RGLVTSPLPAPASLHEPLYLSSEYEAAPGSFGVFTED------VPTCKTCGKTFSCSYTL 487
RGL + G++G TE + C+ CGK F+ +
Sbjct: 285 RGLRS-----------------------GTYGDRTESKAYGSVIHKCEDCGKEFTHTGNF 321
Query: 488 RRHATVHTRERPYECRYCLRSYTQSGDLYRHIRKAHN 524
+RH +HT E+P+ CR C ++++ H K H+
Sbjct: 322 KRHIRIHTGEKPFSCRECSKAFSDPAACKAH-EKTHS 357
Score = 47.4 bits (111), Expect = 4e-05
Identities = 21/51 (41%), Positives = 27/51 (52%)
Query: 474 CKTCGKTFSCSYTLRRHATVHTRERPYECRYCLRSYTQSGDLYRHIRKAHN 524
C CGK F+ + +L H HT E+PY C C + + QS L HIR N
Sbjct: 532 CVMCGKAFTQASSLIAHVRQHTGEKPYVCERCGKRFVQSSQLANHIRHHDN 582
Score = 44.7 bits (104), Expect = 2e-04
Identities = 19/53 (35%), Positives = 29/53 (54%)
Query: 468 TEDVPTCKTCGKTFSCSYTLRRHATVHTRERPYECRYCLRSYTQSGDLYRHIR 520
T+ C C K F+ L+ H +H + P +CR C + +T SG+L RH+R
Sbjct: 442 TDKEHKCPHCDKKFNQVGNLKAHLKIHIADGPLKCRECGKQFTTSGNLKRHLR 494
Score = 44.7 bits (104), Expect = 2e-04
Identities = 18/52 (34%), Positives = 30/52 (57%)
Query: 474 CKTCGKTFSCSYTLRRHATVHTRERPYECRYCLRSYTQSGDLYRHIRKAHNE 525
C C + F+ L+RH +HT E+P +C C +++TQ+ L H+R+ E
Sbjct: 504 CIHCQRQFADPGALQRHVRIHTGEKPCQCVMCGKAFTQASSLIAHVRQHTGE 555
Score = 43.5 bits (101), Expect = 5e-04
Identities = 18/46 (39%), Positives = 25/46 (54%)
Query: 474 CKTCGKTFSCSYTLRRHATVHTRERPYECRYCLRSYTQSGDLYRHI 519
C+ CGK F S L H H RP++C C +++ GDL +HI
Sbjct: 560 CERCGKRFVQSSQLANHIRHHDNIRPHKCSVCSKAFVNVGDLSKHI 605
Score = 42.7 bits (99), Expect = 9e-04
Identities = 17/50 (34%), Positives = 25/50 (50%)
Query: 474 CKTCGKTFSCSYTLRRHATVHTRERPYECRYCLRSYTQSGDLYRHIRKAH 523
C C K F L +H +HT E+PY C C R + + +L H++ H
Sbjct: 588 CSVCSKAFVNVGDLSKHIIIHTGEKPYLCDKCGRGFNRVDNLRSHVKTVH 637
Score = 39.7 bits (91), Expect = 0.008
Identities = 14/47 (29%), Positives = 27/47 (57%)
Query: 474 CKTCGKTFSCSYTLRRHATVHTRERPYECRYCLRSYTQSGDLYRHIR 520
C CG++FS + RH H ++ ++C +C + + Q G+L H++
Sbjct: 420 CDYCGRSFSDPTSKMRHLETHDTDKEHKCPHCDKKFNQVGNLKAHLK 466
>gi|148237270 hypermethylated in cancer 1 isoform 2 [Homo sapiens]
Length = 733
Score = 112 bits (279), Expect = 1e-24
Identities = 141/558 (25%), Positives = 205/558 (36%), Gaps = 112/558 (20%)
Query: 50 TMEFPEHSQQLLQSLREQRSQGFLCDCTVMVGSTQFLAHRAVLASCSPFFQLFYKERELD 109
TME P HS+QLL L QR++GFLCD ++V + F AH+ VLA+ S Y + +
Sbjct: 23 TMEAPGHSRQLLLQLNNQRTKGFLCDVIIVVQNALFRAHKNVLAASSA-----YLKSLVV 77
Query: 110 KRDLVCIHNEIVTAPAFGLLLDFMYAGQL-----------TLRGDTP-VEDVLAAASYLH 157
+L+ + +++V+ F L+LDF+Y G+L G P + VLAAASYL
Sbjct: 78 HDNLLNLDHDMVSPAVFRLVLDFIYTGRLADGAEAAAAAAVAPGAEPSLGAVLAAASYLQ 137
Query: 158 MNDIVKVCKRRLQARAL------------AEADSTKKEEETNSQLPSLEFLSSTSRGTQP 205
+ D+V +CK+RL+ A + + P ++ + G P
Sbjct: 138 IPDLVALCKKRLKRHGKYCHLRGGGGGGGGYAPYGRPGRGLRAATPVIQACYPSPVGPPP 197
Query: 206 SLASAETSG-------HWGKGEWKGSAAPSPTVRPPDEPPMSSGADTTQPGMEVDAPHLR 258
A+ SG H + G + G D ++ P
Sbjct: 198 PPAAEPPSGPEAAVNTHCAELYASGPGPAAALCASERRCSPLCGLDLSKK----SPPGSA 253
Query: 259 APHPPVADVSL-ASPSSSTETIPTNYFSSGISAVSLEPLP-----------------SLD 300
AP P+A+ L P S P Y ++ SL PLP S
Sbjct: 254 APERPLAERELPPRPDSPPSAGPAAYKEPPLALPSLPPLPFQKLEEAAPPSDPFRGGSGS 313
Query: 301 VGPESLRVVEPKDPGGP------------LQGFYPPASAPTSAPA--------------- 333
GPE P P GP L + +P+
Sbjct: 314 PGPE-----PPGRPDGPSLLYRWMKHEPGLGSYGDELGRERGSPSERCEERGGDAAVSPG 368
Query: 334 --PVSAPVPSQAPAPAEAELVQVKVEAIVISDEETDVSDE--QPQGPERAFPSGGAVYGA 389
P+ P + P + + S EET S++ P G +P YG
Sbjct: 369 GPPLGLAPPPRYPGSLDGPGAGGDGDDYKSSSEETGSSEDPSPPGGHLEGYPCPHLAYG- 427
Query: 390 QPSQPEAFED------PGAAGLEEVGPSDHFLPTDPHLPYHLLPGAGQYHRGLVTSPLPA 443
+PE+F D P G PS L + H+ H+ Y R
Sbjct: 428 ---EPESFGDNLYVCIPCGKGF----PSSEQL--NAHVEAHVEEEEALYGRAEAAEVAAG 478
Query: 444 PASLHEPLYLSSEYEA-APGSFGVFTEDVPTCKTCGKTFSCSYTLRRHATVHTRERPYEC 502
A L P + A APG G C +C K++ TLR+H H RPY C
Sbjct: 479 AAGLGPPFGGGGDKVAGAPGGLGELLRPY-RCASCDKSYKDPATLRQHEKTHWLTRPYPC 537
Query: 503 RYCLRSYTQSGDLYRHIR 520
C + +TQ G + RH+R
Sbjct: 538 TICGKKFTQRGTMTRHMR 555
Score = 50.4 bits (119), Expect = 4e-06
Identities = 28/80 (35%), Positives = 38/80 (47%), Gaps = 6/80 (7%)
Query: 474 CKTCGKTFSCSYTLRRHATVHTRERPYECRYCLRSYTQSGDLYRHIRKAHNEDLAKRSKP 533
C CG F+ Y L H +H+ E+PYEC+ C + Q +L H+ K H A +
Sbjct: 565 CDACGMRFTRQYRLTEHMRIHSGEKPYECQVCGGKFAQQRNLISHM-KMHAVGGAAGA-- 621
Query: 534 DPEVGPLLGVQPLPGSPTAD 553
G L G+ LPG P D
Sbjct: 622 ---AGALAGLGGLPGVPGPD 638
>gi|61676186 hypermethylated in cancer 1 isoform 1 [Homo sapiens]
Length = 714
Score = 112 bits (279), Expect = 1e-24
Identities = 141/558 (25%), Positives = 205/558 (36%), Gaps = 112/558 (20%)
Query: 50 TMEFPEHSQQLLQSLREQRSQGFLCDCTVMVGSTQFLAHRAVLASCSPFFQLFYKERELD 109
TME P HS+QLL L QR++GFLCD ++V + F AH+ VLA+ S Y + +
Sbjct: 4 TMEAPGHSRQLLLQLNNQRTKGFLCDVIIVVQNALFRAHKNVLAASSA-----YLKSLVV 58
Query: 110 KRDLVCIHNEIVTAPAFGLLLDFMYAGQL-----------TLRGDTP-VEDVLAAASYLH 157
+L+ + +++V+ F L+LDF+Y G+L G P + VLAAASYL
Sbjct: 59 HDNLLNLDHDMVSPAVFRLVLDFIYTGRLADGAEAAAAAAVAPGAEPSLGAVLAAASYLQ 118
Query: 158 MNDIVKVCKRRLQARAL------------AEADSTKKEEETNSQLPSLEFLSSTSRGTQP 205
+ D+V +CK+RL+ A + + P ++ + G P
Sbjct: 119 IPDLVALCKKRLKRHGKYCHLRGGGGGGGGYAPYGRPGRGLRAATPVIQACYPSPVGPPP 178
Query: 206 SLASAETSG-------HWGKGEWKGSAAPSPTVRPPDEPPMSSGADTTQPGMEVDAPHLR 258
A+ SG H + G + G D ++ P
Sbjct: 179 PPAAEPPSGPEAAVNTHCAELYASGPGPAAALCASERRCSPLCGLDLSKK----SPPGSA 234
Query: 259 APHPPVADVSL-ASPSSSTETIPTNYFSSGISAVSLEPLP-----------------SLD 300
AP P+A+ L P S P Y ++ SL PLP S
Sbjct: 235 APERPLAERELPPRPDSPPSAGPAAYKEPPLALPSLPPLPFQKLEEAAPPSDPFRGGSGS 294
Query: 301 VGPESLRVVEPKDPGGP------------LQGFYPPASAPTSAPA--------------- 333
GPE P P GP L + +P+
Sbjct: 295 PGPE-----PPGRPDGPSLLYRWMKHEPGLGSYGDELGRERGSPSERCEERGGDAAVSPG 349
Query: 334 --PVSAPVPSQAPAPAEAELVQVKVEAIVISDEETDVSDE--QPQGPERAFPSGGAVYGA 389
P+ P + P + + S EET S++ P G +P YG
Sbjct: 350 GPPLGLAPPPRYPGSLDGPGAGGDGDDYKSSSEETGSSEDPSPPGGHLEGYPCPHLAYG- 408
Query: 390 QPSQPEAFED------PGAAGLEEVGPSDHFLPTDPHLPYHLLPGAGQYHRGLVTSPLPA 443
+PE+F D P G PS L + H+ H+ Y R
Sbjct: 409 ---EPESFGDNLYVCIPCGKGF----PSSEQL--NAHVEAHVEEEEALYGRAEAAEVAAG 459
Query: 444 PASLHEPLYLSSEYEA-APGSFGVFTEDVPTCKTCGKTFSCSYTLRRHATVHTRERPYEC 502
A L P + A APG G C +C K++ TLR+H H RPY C
Sbjct: 460 AAGLGPPFGGGGDKVAGAPGGLGELLRPY-RCASCDKSYKDPATLRQHEKTHWLTRPYPC 518
Query: 503 RYCLRSYTQSGDLYRHIR 520
C + +TQ G + RH+R
Sbjct: 519 TICGKKFTQRGTMTRHMR 536
Score = 50.4 bits (119), Expect = 4e-06
Identities = 28/80 (35%), Positives = 38/80 (47%), Gaps = 6/80 (7%)
Query: 474 CKTCGKTFSCSYTLRRHATVHTRERPYECRYCLRSYTQSGDLYRHIRKAHNEDLAKRSKP 533
C CG F+ Y L H +H+ E+PYEC+ C + Q +L H+ K H A +
Sbjct: 546 CDACGMRFTRQYRLTEHMRIHSGEKPYECQVCGGKFAQQRNLISHM-KMHAVGGAAGA-- 602
Query: 534 DPEVGPLLGVQPLPGSPTAD 553
G L G+ LPG P D
Sbjct: 603 ---AGALAGLGGLPGVPGPD 619
>gi|139394599 hypermethylated in cancer 2 [Homo sapiens]
Length = 615
Score = 107 bits (266), Expect = 4e-23
Identities = 148/564 (26%), Positives = 213/564 (37%), Gaps = 127/564 (22%)
Query: 51 MEFPEHSQQLLQSLREQRSQGFLCDCTVMVGSTQFLAHRAVLASCSPFFQLFYKERELDK 110
ME P HS+QLL L +QR++GFLCD +MV ++ F AH+ VLA+ S +F+
Sbjct: 23 MELPSHSKQLLLQLNQQRTKGFLCDVIIMVENSIFRAHKNVLAASSIYFKSLVLH----- 77
Query: 111 RDLVCIHNEIVTAPAFGLLLDFMYAGQLTLRGDTPVE----DVLAAASYLHMNDIVKVCK 166
+L+ + ++V++ F +LDF+Y G+L L D P E +L AASYL + ++ +C+
Sbjct: 78 DNLINLDTDMVSSTVFQQILDFIYTGKL-LPSDQPAEPNFSTLLTAASYLQLPELAALCR 136
Query: 167 RRLQARALAEADSTKKEEETNSQLPSLEFLSSTSRGTQPSLASAETSGHWGKGEWKGSAA 226
R+L+ RA S + ST G P T+ + ++G
Sbjct: 137 RKLK-RAGKPFGSGR--------------AGSTGMGRPPRSQRLSTASVI-QARYQGLVD 180
Query: 227 PSPTVRPPDEPPMSSGADTT--QPGMEVDAPH--LRAPHPPVADVSLASPSSSTETIPTN 282
P E P + G+D G D+ RA P + L SSS TN
Sbjct: 181 GRKGAHAPQELPQAKGSDDELFLGGSNQDSVQGLGRAVCPAGGEAGLGGCSSS-----TN 235
Query: 283 YFSSGIS-------AVSLEPLPSLDVGPESLRVVEPKDPGGPLQGFYPPASAPTSAPAPV 335
S G + PLP GP L + G P ASAP A +
Sbjct: 236 GSSGGCEQELGLDLSKKSPPLPPATPGPH-LTPDDAAQLSDSQHGSPPAASAPPVANSAS 294
Query: 336 SAPVPSQAPAPAEAE--------LVQV-------------------KVEAIVISDEET-- 366
+ + P + E L++ K E + S E
Sbjct: 295 YSELGGTPDEPMDLEGAEDNHLSLLEAPGGQPRKSLRHSTRKKEWGKKEPVAGSPFERRE 354
Query: 367 -----DVSDEQPQGPERAFPSGGAVYGAQPSQP----------------EAFEDPGAAGL 405
E+ +G P+G GA PS P +A ED +G
Sbjct: 355 AGPKGPCPGEEGEGVGDRVPNGILASGAGPSGPYGEPPYPCKEEEENGKDASEDSAQSGS 414
Query: 406 EEVGPSDHFLPTDPHLPYH------LLPGAGQY-----HRGLVTS-PLPAPASLH--EPL 451
E G S H H Y + G Y +G +S L A H E L
Sbjct: 415 E--GGSGH---ASAHYMYRQEGYETVSYGDNLYVCIPCAKGFPSSEQLNAHVETHTEEEL 469
Query: 452 YLSSE--YEAAPGSFGVFTEDVPT-------------CKTCGKTFSCSYTLRRHATVHTR 496
++ E YE G ED+ C C KT+ TLR+H H
Sbjct: 470 FIKEEGAYETGSGGAEEEAEDLSAPSAAYTAEPRPFKCSVCEKTYKDPATLRQHEKTHWL 529
Query: 497 ERPYECRYCLRSYTQSGDLYRHIR 520
RP+ C C + +TQ G + RH+R
Sbjct: 530 TRPFPCNICGKMFTQRGTMTRHMR 553
Score = 49.7 bits (117), Expect = 7e-06
Identities = 20/47 (42%), Positives = 27/47 (57%)
Query: 474 CKTCGKTFSCSYTLRRHATVHTRERPYECRYCLRSYTQSGDLYRHIR 520
C CG F+ Y L H VH+ E+PYEC+ C +TQ +L H+R
Sbjct: 563 CDECGMRFTRQYRLTEHMRVHSGEKPYECQLCGGKFTQQRNLISHLR 609
>gi|47679080 zinc finger and BTB domain containing 46 [Homo sapiens]
Length = 589
Score = 105 bits (262), Expect = 1e-22
Identities = 122/507 (24%), Positives = 194/507 (38%), Gaps = 74/507 (14%)
Query: 51 MEFPEHSQQLLQSLREQRSQGFLCDCTVMVGSTQFLAHRAVLASCSPFFQLFYKERELDK 110
ME H + LL+ L EQR G LCD V+V F AH+ VL S +F+ Y + +
Sbjct: 8 MEITSHYRHLLRELNEQRQHGVLCDVCVVVEGKVFKAHKNVLLGSSRYFKTLYCQVQKTS 67
Query: 111 RDLVCIHNEIVTAPAFGLLLDFMYAGQLTLRGDTPVEDVLAAASYLHMNDIVKVCKRRLQ 170
H +IVTA F ++DFMY+ L L +E V++AAS+L M DIV+ C ++
Sbjct: 68 EQATVTHLDIVTAQGFKAIIDFMYSAHLALTSRNVIE-VMSAASFLQMTDIVQACHDFIK 126
Query: 171 ARALAEADSTKKEEETNSQLPSLEFLSSTSRGTQPSLASAETSGHWGKGEWKGSAAPSPT 230
A A + + + +L E +S+S T+ +L SA +G + SP
Sbjct: 127 A-----ALDISIKSDASDELAEFEIGASSSSSTE-ALISAVMAGR----------SISPW 170
Query: 231 VRPPDEPPMSSGADTTQPGMEVDAPHLRAPHPPVADVSLASPSSSTETIPTNYFSSGISA 290
+ P SSG + + + + P AD G
Sbjct: 171 LARRTSPADSSGDSAIASCHDGGSSYGKEDQEPKAD--------------------GPDD 210
Query: 291 VSLEPLPSLDVGPESLRVVEPKDPGGPLQGFYPPASAPTSAPAPVSAPVPSQAPAPAEAE 350
VS +PL DVG LR+ E + G P++ + S A P
Sbjct: 211 VSSQPLWPGDVGYGPLRIKEEQVSPSQYGGSELPSAKDGAVQNSFSEQSAGDAWQPTGRR 270
Query: 351 LVQVKVEAIVISDEETDVSDEQPQGPERAF-PSGGAVYGAQPSQPEAFEDPGAAGLEEVG 409
+ E + ++ + D + P +F P+ G + ++ S + ++
Sbjct: 271 KNRKNKETVRHITQQVE-DDSRASSPVPSFLPTSGWPFSSRDSNADLSVTEASSSDSRGE 329
Query: 410 PSDHFLPTDPHLPYHLLPGAGQY-------------HRGLVTSPLPAP-ASLHEPLYLSS 455
++ + + LL G Y H+ + L A S + L L +
Sbjct: 330 RAELYAQVEE----GLLGGEASYLGPPLTPEKDDALHQATAVANLRAALMSKNSLLSLKA 385
Query: 456 EYEAAPGSF-------GVFTEDVPTCKTCGKTFSCSY---------TLRRHATVHTRERP 499
+ GS G + + K F C Y L+RH HT ERP
Sbjct: 386 DVLGDDGSLLFEYLPRGAHSLSLNEFTVIRKKFKCPYCSFSAMHQCILKRHMRSHTGERP 445
Query: 500 YECRYCLRSYTQSGDLYRHIRKAHNED 526
Y C C + +T+ + RH H++D
Sbjct: 446 YPCEICGKKFTRREHMKRH-TLVHSKD 471
>gi|32469511 B-cell CLL/lymphoma 6, member B (zinc finger protein)
[Homo sapiens]
Length = 480
Score = 102 bits (253), Expect = 1e-21
Identities = 125/477 (26%), Positives = 170/477 (35%), Gaps = 67/477 (14%)
Query: 52 EFPEHSQQLLQSLREQRSQGFLCDCTVMVGSTQFLAHRAVLASCSPFFQLFYKERELDKR 111
EF HS +L +L E R +G L D T++VG AH+AVL +CS FF ++ R
Sbjct: 16 EFTRHSSDVLGNLNELRLRGILTDVTLLVGGQPLRAHKAVLIACSGFFYSIFRGRAGVGV 75
Query: 112 DLVCIHNEIVTAPAFGLLLDFMYAGQLTLRGDTPVEDVLAAASYLHMNDIVKVCKRRLQA 171
D++ + A F LLDFMY +L L T VLAAA+YL M +V+ C R +QA
Sbjct: 76 DVLSLPGG-PEARGFAPLLDFMYTSRLRLSPAT-APAVLAAATYLQMEHVVQACHRFIQA 133
Query: 172 RALAEADSTKKEEETNSQLPSLEFLSSTSRGTQPSLASAETSGHWGKGEWKGSAAPSPTV 231
E L LE T P + + GH S + P
Sbjct: 134 ----------SYEPLGISLRPLEAEPPTPPTAPPPGSPRRSEGHPDPPTESRSCSQGPPS 183
Query: 232 RPPDEPPMSSGADTTQPGMEVDAPHLRAPHPPVADVSLASPSSSTETIPTNYFSSGISAV 291
+P + + A SL SS + P SG A
Sbjct: 184 PASPDPKACNWKKYKYIVLNSQASQAG---------SLVGERSSGQPCPQARLPSGDEAS 234
Query: 292 SLEPLPSLDVGPESLRVVEPKDPGGPLQGFYPPASAPTSAPAPVSAPVPSQAPAPAEAEL 351
S S E GP+ G P S +P +A V + APA
Sbjct: 235 SSSSSSSSSSSEE-----------GPIPG-------PQSRLSPTAATVQFKCGAPASTPY 276
Query: 352 VQVKVEAIVISDEETDVSDEQPQGPERAFP-SGGAVYGAQPSQPEAFEDPGAAGLEEVGP 410
+ + D ERA P G + Q + A ++GL+ + P
Sbjct: 277 LLT-----------SQAQDTSGSPSERARPLPGSEFFSCQNCEAVA---GCSSGLDSLVP 322
Query: 411 SDHFLPTDPHLPYHLLPGAGQY--HRGLVTSPLPAPASL-----HEPLYLSSEYEAAPGS 463
D P L G HR + T P S+ + P L + G
Sbjct: 323 GDEDKPYKCQLCRSSFRYKGNLASHRTVHTGEKPYHCSICGARFNRPANLKTHSRIHSG- 381
Query: 464 FGVFTEDVPTCKTCGKTFSCSYTLRRHATVHTRERPYECRYCLRSYTQSGDLYRHIR 520
E C+TCG F LR H +HT E+PY C C + L H+R
Sbjct: 382 -----EKPYKCETCGSRFVQVAHLRAHVLIHTGEKPYPCPTCGTRFRHLQTLKSHVR 433
>gi|109134351 zinc finger and BTB domain containing 44 [Homo
sapiens]
Length = 453
Score = 99.8 bits (247), Expect = 6e-21
Identities = 108/480 (22%), Positives = 184/480 (38%), Gaps = 64/480 (13%)
Query: 56 HSQQLLQSLREQRSQGFLCDCTVMVGSTQFLAHRAVLASCSPFFQL-FYKERELDKRDLV 114
HSQ++L L R+ G CD T+ V F AH+ VLA+CS FF+ + E + ++++
Sbjct: 13 HSQEMLGKLNMLRNDGHFCDITIRVQDKIFRAHKVVLAACSDFFRTKLVGQAEDENKNVL 72
Query: 115 CIHNEIVTAPAFGLLLDFMYAGQLTLRGDTPVEDVLAAASYLHMNDIVKVCKRRLQARAL 174
+H+ VT F LL++ Y L++ + + DVLAAASY+ M + C +++ L
Sbjct: 73 DLHH--VTVTGFIPLLEYAYTATLSINTEN-IIDVLAAASYMQMFSVASTCSEFMKSSIL 129
Query: 175 AEADSTKKEEETNSQLPSLEFLSSTSRGTQPSLASAETS--------GHWGKGEWKGSAA 226
+++ E+ ++ + + TSR S S+E S + + K
Sbjct: 130 WNTPNSQPEKGLDAGQENNSNCNFTSRDGSISPVSSECSVVERTIPVCRESRRKRKSYIV 189
Query: 227 PSPTVRPPDEPPMSSGADTTQPG-MEVDAPHLRAPHPPVADVSLASPSSSTETIPTNYFS 285
SP E P+ G T+ P + A + + PV D SLA P + F
Sbjct: 190 MSP------ESPVKCGTQTSSPQVLNSSASYSENRNQPV-DSSLAFPWT---------FP 233
Query: 286 SGISAVSLEPLPSLDVGPESLRVVEPKDPGGPLQGFYPPASAPTSAPAPVSAPVPSQAPA 345
GI +L + P + G + + S T+ P V +
Sbjct: 234 FGIDRRIQPEKVKQAENTRTLELPGPSETGRRMADYVTCESTKTTLPLGTEEDVRVKVER 293
Query: 346 PAEAELVQ-----VKVEAIVISDEETDVSDEQPQGPERAFPSGGAVYGAQPSQPEAFEDP 400
++ E+ + V +SD++T EQ Q P ++ E
Sbjct: 294 LSDEEVHEEVSQPVSASQSSLSDQQTVPGSEQVQEDLLISPQSSSIGSVDEGVSEGLPTL 353
Query: 401 GAAGLEEVGPSDHFLPTDPHLPY--HLLPGAGQYHRGLVTSPLPAPASLHEPLYLSSEYE 458
+ P D + PY ++ P R P+P P
Sbjct: 354 QSTSSTNAPPDDDDRLENVQYPYQLYIAPSTSSTER-------PSPNGPDRPF------- 399
Query: 459 AAPGSFGVFTEDVPTCKTCGKTFSCSYTLRRHATVHTRERPYECRYCLRSYTQSGDLYRH 518
C TCG F+ L++H +H+ +P++C C + +T++ L H
Sbjct: 400 --------------QCPTCGVRFTRIQNLKQHMLIHSGIKPFQCDRCGKKFTRAYSLKMH 445
>gi|223972645 zinc finger protein 509 [Homo sapiens]
Length = 765
Score = 95.9 bits (237), Expect = 9e-20
Identities = 118/486 (24%), Positives = 185/486 (38%), Gaps = 44/486 (9%)
Query: 56 HSQQLLQSLREQRSQGFLCDCTVMVGSTQFLAHRAVLASCSPFFQLFYKERELDKRDLVC 115
HS LLQ L EQR QG LCDC ++V F AH+ VLA+ S +F+ ++ K D+
Sbjct: 7 HSCHLLQQLHEQRIQGLLCDCMLVVKGVCFKAHKNVLAAFSQYFRSLFQNSSSQKNDV-- 64
Query: 116 IHNEIVTAPAFGLLLDFMYAGQLTLRGDTPVEDVLAAASYLHMNDIVKVCKRRLQARALA 175
H ++ G +LDFMY L L D ++ +L A L + +++ +C L++ +
Sbjct: 65 FHLDVKNVSGIGQILDFMYTSHLDLNQDN-IQVMLDTAQCLQVQNVLSLCHTFLKSATVV 123
Query: 176 E-----ADSTKKEEET--------NSQLPSLEFLSSTSRGTQPSLASAETSGHWGKGEWK 222
+ +ST + T S+ L S Q + E+ H +
Sbjct: 124 QPPGMPCNSTLSLQSTLTPDATCVISENYPPHLLQECSADAQQNKTLDESHPHASPSVNR 183
Query: 223 GSAAPSPTVRPPDEPPMSSGADTTQPGMEVDAPH-LRAPHPPVADVSLASPSSSTETIPT 281
+A + + PD S G+ T P + + + LR + A PS
Sbjct: 184 HHSAGEISKQAPD---TSDGSCTELPFKQPNYYYKLRNFYSKQYHKHAAGPSQERVVEQP 240
Query: 282 NYFSSGISAVSLEPLPSLDVGPESLRVVEPKDPGG----PLQGFYPPASAPTSAPAPVSA 337
FS+ ++E P E + P P+ P + + PV
Sbjct: 241 FAFSTSTDLTTVESQPCAVSHSECILESPEHLPSNFLAQPVNDSAPHPESDATCQQPVKQ 300
Query: 338 PVPSQAPAPAEAELVQVKVEAIVISDEETDVSDEQPQGPERAFPSGGAVYGAQPSQPEAF 397
+A + ++ + A +S+ ++D D + E A S + A E
Sbjct: 301 MRLKKAIHLKKLNFLKSQKYAEQVSEPKSD--DGLTKRLESA--SKNTLEKASSQSAEEK 356
Query: 398 EDPGAAGLEEVG-PSDHFLPTDPHL---PYHLLPGAGQYHRGLVTSPLPAPASLHEPLYL 453
E E S+ P DP L QY L P P++L L+
Sbjct: 357 ESEEVVSCENFNCISETERPEDPAALEDQSQTLQSQRQYACELCGKPFKHPSNLE--LHK 414
Query: 454 SSEYEAAPGSFGVFTEDVPTCKTCGKTFSCSYTLRRHATVHTRERPYECRYCLRSYTQSG 513
S P C CGK FS + L+ H H+ E+PY C C + + SG
Sbjct: 415 RSHTGEKPFE----------CNICGKHFSQAGNLQTHLRRHSGEKPYICEICGKRFAASG 464
Query: 514 DLYRHI 519
D+ RHI
Sbjct: 465 DVQRHI 470
Score = 53.9 bits (128), Expect = 4e-07
Identities = 24/52 (46%), Positives = 31/52 (59%)
Query: 469 EDVPTCKTCGKTFSCSYTLRRHATVHTRERPYECRYCLRSYTQSGDLYRHIR 520
+ V TC CGK+F+ L +H HT ERPY C C + + SGDL RH+R
Sbjct: 504 DKVFTCDECGKSFNMQRKLVKHRIRHTGERPYSCSACGKCFGGSGDLRRHVR 555
Score = 53.9 bits (128), Expect = 4e-07
Identities = 35/98 (35%), Positives = 43/98 (43%), Gaps = 6/98 (6%)
Query: 473 TCKTCGKTFSCSYTLRRHATVHTRERPYECRYCLRSYTQSGDLYRHIRKAHNEDLAKRSK 532
+C CGK F S LRRH HT E+PY C C + +T+S L RH +K H K
Sbjct: 536 SCSACGKCFGGSGDLRRHVRTHTGEKPYTCEICNKCFTRSAVLRRH-KKMH----CKAGD 590
Query: 533 PDPEVGPLLGVQPLPGSPTADRQSSSGGGPPKDFVLAP 570
P+V L Q + S QSS L P
Sbjct: 591 ESPDVLEELS-QAIETSDLEKSQSSDSFSQDTSVTLMP 627
Score = 50.4 bits (119), Expect = 4e-06
Identities = 20/52 (38%), Positives = 30/52 (57%)
Query: 474 CKTCGKTFSCSYTLRRHATVHTRERPYECRYCLRSYTQSGDLYRHIRKAHNE 525
C+ CGK F L H HT E+P+EC C + ++Q+G+L H+R+ E
Sbjct: 397 CELCGKPFKHPSNLELHKRSHTGEKPFECNICGKHFSQAGNLQTHLRRHSGE 448
Score = 46.2 bits (108), Expect = 8e-05
Identities = 19/53 (35%), Positives = 31/53 (58%), Gaps = 1/53 (1%)
Query: 474 CKTCGKTFSCSYTLRRHATVHTRERPYECRYCLRSYTQSGDLYRHIRKAHNED 526
C+ CGK F+ S ++RH +H+ E+P+ C C R ++ +L H +K H D
Sbjct: 453 CEICGKRFAASGDVQRHIIIHSGEKPHLCDICGRGFSNFSNLKEH-KKTHTAD 504
>gi|94721342 zinc finger and BTB domain containing 8A [Homo sapiens]
Length = 441
Score = 93.6 bits (231), Expect = 4e-19
Identities = 63/217 (29%), Positives = 104/217 (47%), Gaps = 19/217 (8%)
Query: 51 MEFPEHSQQLLQSLREQRSQGFLCDCTVMVGSTQFLAHRAVLASCSPFFQLFYKERELDK 110
ME H LLQ L EQR Q CDC+++V F AHR VL + S +F++ + +
Sbjct: 1 MEISSHQSHLLQQLNEQRRQDVFCDCSILVEGKVFKAHRNVLFASSGYFKMLLSQNSKET 60
Query: 111 RDLVCIHNEIVTAPAFGLLLDFMYAGQLTLRGDTPVEDVLAAASYLHMNDIVKVCKRRLQ 170
+ + F ++LDF+Y+G+L+L G +E V++AAS+L M D++ VCK ++
Sbjct: 61 SQPTTATFQAFSPDTFTVILDFVYSGKLSLTGQNVIE-VMSAASFLQMTDVISVCKTFIK 119
Query: 171 ARALAEADSTKKEEETNSQLPSLEFLSSTSRGTQPSLASAETSGHWGKGEWKGSAAPSPT 230
+ D ++KE++ + SL + S G E S + G +GS++P
Sbjct: 120 ----SSLDISEKEKD---RYFSLSDKDANSNG-------VERSSFYSGGWQEGSSSPRSH 165
Query: 231 VRPPDEPPMSSGADTTQ----PGMEVDAPHLRAPHPP 263
+ P + SG + P + + A H P
Sbjct: 166 LSPEQGTGIISGKSWNKYNYHPASQKNTQQPLAKHEP 202
Score = 41.2 bits (95), Expect = 0.003
Identities = 20/61 (32%), Positives = 28/61 (45%), Gaps = 4/61 (6%)
Query: 467 FTEDVPT----CKTCGKTFSCSYTLRRHATVHTRERPYECRYCLRSYTQSGDLYRHIRKA 522
F +D+P C C L+RH HT ERPY C+ C + +++ L H R
Sbjct: 273 FPDDLPRMRFKCPYCTHVVKRKADLKRHLRCHTGERPYPCQACGKRFSRLDHLSSHFRTI 332
Query: 523 H 523
H
Sbjct: 333 H 333
>gi|224591419 zinc finger and BTB domain containing 8B [Homo
sapiens]
Length = 495
Score = 88.2 bits (217), Expect = 2e-17
Identities = 62/185 (33%), Positives = 92/185 (49%), Gaps = 24/185 (12%)
Query: 51 MEFPEHSQQLLQSLREQRSQGFLCDCTVMVGSTQFLAHRAVLASCSPFFQLFYKERELDK 110
ME + +LL L EQR + F CDC+++V F AHR +L + S +F+ D
Sbjct: 1 MEMQSYYAKLLGELNEQRKRDFFCDCSIIVEGRIFKAHRNILFANSGYFRALLIHYIQDS 60
Query: 111 RDLVCIHNEIVTAPAFGLLLDFMYAGQLTLRGDTPVEDVLAAASYLHMNDIVKVCKRRLQ 170
+IVT+ AF ++LDF+Y+G+L L G+ +E V++AASYL MND+V CK ++
Sbjct: 61 GRHSTASLDIVTSDAFSIILDFLYSGKLDLCGENVIE-VMSAASYLQMNDVVNFCKTYIR 119
Query: 171 ---------------------ARALAEADSTKKEEETNSQLPSLEFLSSTSRGTQPSLAS 209
A A A A + + +S+ PS TS GT+ SL S
Sbjct: 120 SSLDICRKMEKEAAVAAAVAAAAAAAAAAAAAAAHQVDSESPS-SGREGTSCGTK-SLVS 177
Query: 210 AETSG 214
+ G
Sbjct: 178 SPAEG 182
Score = 39.3 bits (90), Expect = 0.010
Identities = 18/53 (33%), Positives = 23/53 (43%)
Query: 474 CKTCGKTFSCSYTLRRHATVHTRERPYECRYCLRSYTQSGDLYRHIRKAHNED 526
C C T L+RH HT ERPY C C + +T+ L H H +
Sbjct: 343 CPFCPYTAKQKGILKRHIRSHTGERPYPCETCGKRFTRQEHLRSHALSVHRSN 395
Score = 39.3 bits (90), Expect = 0.010
Identities = 18/38 (47%), Positives = 24/38 (63%), Gaps = 1/38 (2%)
Query: 474 CKTCGKTFSCSYTLRRHA-TVHTRERPYECRYCLRSYT 510
C+TCGK F+ LR HA +VH RP C+ C R++T
Sbjct: 371 CETCGKRFTRQEHLRSHALSVHRSNRPIICKGCRRTFT 408
>gi|23308693 zinc finger and BTB domain containing 9 [Homo sapiens]
Length = 473
Score = 88.2 bits (217), Expect = 2e-17
Identities = 124/479 (25%), Positives = 174/479 (36%), Gaps = 67/479 (13%)
Query: 44 PFPSWGTMEFPEHSQQLLQSLREQRSQGFLCDCTVMVGSTQFLAHRAVLASCSPFFQLFY 103
P P +EFP+HS LL+SL R +G CD +++V + AH+AVLA+ SP+F
Sbjct: 18 PAPRTIQIEFPQHSSSLLESLNRHRLEGKFCDVSLLVQGRELRAHKAVLAAASPYFHDKL 77
Query: 104 KERELDKRDLVCIHNEIVTAPAFGLLLDFMYAGQLTLRGDTPVEDVLAAASYLHMNDIVK 163
+ + L ++ A AF LL +Y+G+L L D + L AS L M +V
Sbjct: 78 LLGDAPRLTL----PSVIEADAFEGLLQLIYSGRLRLPLDA-LPAHLLVASGLQMWQVVD 132
Query: 164 VCKRRLQARALAEADSTKKEEETNSQLPSLEFLSSTSRGTQPSLASAETSGHWGKGEWKG 223
C L R L + NS L SST G W
Sbjct: 133 QCSEIL--RELETSGGGISARGGNSYHALLSTTSST-------------------GGWCI 171
Query: 224 SAAPSPTVRPPDEPPMSSGADTTQPGMEVDAPHLRAPHPPVADVSLASPSSSTETIPTNY 283
++P T P+ S A T P ++P + + E +
Sbjct: 172 RSSPFQT-------PVQSSASTESPA-STESPVGGEGSELGEVLQIQVEEEEEEEEDDDD 223
Query: 284 FSSGISAVSLEPLPSLDVGPESLRVVEPKDPGGPLQGFYPPASAPTSAPAPVSAPVPSQA 343
G + +S P P G V P+ P GP P + P P SAP+ A
Sbjct: 224 EDQGSATLSQTPQPQRVSG------VFPR-PHGPHP--LPMTATPRKLPEGESAPLELPA 274
Query: 344 PAPAEAELVQVKVEAIVISDEETDVSDEQPQG--PERAFPSGGAVYGAQPSQPEAFEDPG 401
P ++ +K E EE S QP G E SGG G + F P
Sbjct: 275 PPALPPKIFYIKQEPFE-PKEEISGSGTQPGGAKEETKVFSGGDTEG---NGELGFLLPS 330
Query: 402 AAGLEEVGPSDHFLPTDPHLPYHLLPGAGQYHRGLVTSPLPAPASLHEPLYLSSEYEAAP 461
G G + P D H +L G G P A ++H P+ L A
Sbjct: 331 GPGPTSGGGGPSWKPVDLH-GNEILSGGG--------GPGGAGQAVHGPVKLGGTPPADG 381
Query: 462 GSFGVFTEDVPTCKTCGKTFSCSYTLRRHATVHTRERPYECRYCLRSYTQSGDLYRHIR 520
FG CGK F+ RH + RP+ C C + + L H++
Sbjct: 382 KRFGCL---------CGKRFAVKPKRDRHIMLTFSLRPFGCGICNKRFKLKHHLTEHMK 431
>gi|197927147 B-cell lymphoma 6 protein isoform 2 [Homo sapiens]
Length = 650
Score = 87.0 bits (214), Expect = 4e-17
Identities = 127/581 (21%), Positives = 210/581 (36%), Gaps = 126/581 (21%)
Query: 46 PSWGTMEFPEHSQQLLQSLREQRSQGFLCDCTVMVGSTQFLAHRAVLASCSPFFQLFYKE 105
P+ ++F H+ +L +L RS+ L D ++V QF AH+ VL +CS F + +
Sbjct: 4 PADSCIQFTRHASDVLLNLNRLRSRDILTDVVIVVSREQFRAHKTVLMACSGLFYSIFTD 63
Query: 106 RELDKRDLVCIHNEIVTAPAFGLLLDFMYAGQLTLRGDTPVEDVLAAASYLHMNDIVKVC 165
+ ++ + EI F +LLDFMY +L LR + + V+A A YL M +V C
Sbjct: 64 QLKCNLSVINLDPEI-NPEGFCILLDFMYTSRLNLR-EGNIMAVMATAMYLQMEHVVDTC 121
Query: 166 KRRLQA--RALAEADSTKKEEETNSQ-LPSLEFLSSTSRGTQPS---LASAE--TSGHWG 217
++ ++A + A +EE NS+ L + ++ R + L SA S +
Sbjct: 122 RKFIKASEAEMVSAIKPPREEFLNSRMLMPQDIMAYRGREVVENNLPLRSAPGCESRAFA 181
Query: 218 KGEWKGSAAPSPTVRPPDEPPMSSGADTTQPGMEVDAPHLRAPHPPVADVSLASPSSSTE 277
+ G + P + P+SS + + +V P + P P A P S
Sbjct: 182 PSLYSGLSTPPASYSMYSHLPVSSLLFSDEEFRDVRMP-VANPFPK----ERALPCDSAR 236
Query: 278 TIPTNYFSSGISAVSLEPLPSLDVGPE--SLRVVEPKDP----------GGPLQGFYPPA 325
+P Y P+L+V P + PK+ +G P A
Sbjct: 237 PVPGEY-----------SRPTLEVSPNVCHSNIYSPKETIPEEARSDMHYSVAEGLKPAA 285
Query: 326 SAPTSAPAPVSAPVPSQAPAPAEAELVQVKVEAI--------VISDEETDVSDEQPQGPE 377
+ +AP + P+ + + + E ++S + SD QP P
Sbjct: 286 PSARNAPYFPCDKASKEEERPSSEDEIALHFEPPNAPLNRKGLVSPQSPQKSDCQPNSPT 345
Query: 378 RAFPS--------GGAVYGAQPSQPEAF-------------------EDPGAAGLEEVGP 410
+ S G+ P+ P+A E P A L + P
Sbjct: 346 ESCSSKNACILQASGSPPAKSPTDPKACNWKKYKFIVLNSLNQNAKPEGPEQAELGRLSP 405
Query: 411 SDHFLP---TDPHLPYHL-------LPGAGQ-------------YHRGLVTSPLPAPASL 447
+ P P P +L L +G+ +R + SP + S
Sbjct: 406 RAYTAPPACQPPMEPENLDLQSPTKLSASGEDSTIPQASRLNNIVNRSMTGSPRSSSES- 464
Query: 448 HEPLYLSSEYEAAPGSFG-------------VFTEDVP----------------TCKTCG 478
H PLY+ + GS F E++ C CG
Sbjct: 465 HSPLYMHPPKCTSCGSQSPQHAEMCLHTAGPTFPEEMGETQSEYSDSSCGEKPYRCNICG 524
Query: 479 KTFSCSYTLRRHATVHTRERPYECRYCLRSYTQSGDLYRHI 519
F+ L+ H +H+ E+PY+C C + Q L H+
Sbjct: 525 AQFNRPANLKTHTRIHSGEKPYKCETCGARFVQVAHLRAHV 565
Score = 45.8 bits (107), Expect = 1e-04
Identities = 18/50 (36%), Positives = 25/50 (50%)
Query: 474 CKTCGKTFSCSYTLRRHATVHTRERPYECRYCLRSYTQSGDLYRHIRKAH 523
C+ CG F TL+ H +HT E+PY C C + L H+R+ H
Sbjct: 576 CEICGTRFRHLQTLKSHLRIHTGEKPYHCEKCNLHFRHKSQLRLHLRQKH 625
Score = 42.4 bits (98), Expect = 0.001
Identities = 78/348 (22%), Positives = 115/348 (33%), Gaps = 59/348 (16%)
Query: 210 AETSGHWGKGEWKGSAAPSPTVRPPDEPPMSSGADTTQPGMEVD-APHLRAPHPPVADVS 268
A + H+ E AAPS P P + + +P E + A H P+ P+
Sbjct: 269 ARSDMHYSVAEGLKPAAPSAR-NAPYFPCDKASKEEERPSSEDEIALHFEPPNAPLNRKG 327
Query: 269 LASPSSSTET-----IPTNYFSSGISAV---SLEPLPSLDVGPESLRVVEPK-------- 312
L SP S ++ PT SS + + S P P++ + K
Sbjct: 328 LVSPQSPQKSDCQPNSPTESCSSKNACILQASGSPPAKSPTDPKACNWKKYKFIVLNSLN 387
Query: 313 ---DPGGPLQGFY----------PPASAPTSAPAPVSAPVPSQAPAPAEAELV-QVKVEA 358
P GP Q PPA P P + P++ A E + Q
Sbjct: 388 QNAKPEGPEQAELGRLSPRAYTAPPACQPPMEPENLDLQSPTKLSASGEDSTIPQASRLN 447
Query: 359 IVISDEETDV--SDEQPQGPERAFPSGGAVYGAQPSQPE--AFEDPGAAGLEEVGP--SD 412
+++ T S + P P G+Q Q G EE+G S+
Sbjct: 448 NIVNRSMTGSPRSSSESHSPLYMHPPKCTSCGSQSPQHAEMCLHTAGPTFPEEMGETQSE 507
Query: 413 HFLPTDPHLPYHLLPGAGQYHRGLVTSPLPAPASLHEPLYLSSEYEAAPGSFGVFTEDVP 472
+ + PY Q++R PA H ++ E
Sbjct: 508 YSDSSCGEKPYRCNICGAQFNR-------PANLKTHTRIHSG--------------EKPY 546
Query: 473 TCKTCGKTFSCSYTLRRHATVHTRERPYECRYCLRSYTQSGDLYRHIR 520
C+TCG F LR H +HT E+PY C C + L H+R
Sbjct: 547 KCETCGARFVQVAHLRAHVLIHTGEKPYPCEICGTRFRHLQTLKSHLR 594
>gi|8923885 myoneurin [Homo sapiens]
Length = 610
Score = 87.0 bits (214), Expect = 4e-17
Identities = 50/132 (37%), Positives = 75/132 (56%), Gaps = 5/132 (3%)
Query: 51 MEFPEHSQQLLQSLREQRSQGFLCDCTVMVGSTQFLAHRAVLASCSPFFQLFYKERELDK 110
M++ H + LL+ L +QR GFLCDCT+++G QF AHR VLAS S +F Y+
Sbjct: 1 MQYSHHCEHLLERLNKQREAGFLCDCTIVIGEFQFKAHRNVLASFSEYFGAIYRS---TS 57
Query: 111 RDLVCIHNEIVTAPAFGLLLDFMYAGQLTLRGDTPVEDVLAAASYLHMNDIVKVCKRRLQ 170
+ V + V A F LL+F+Y G L L V+++ AA YL + ++V CK +++
Sbjct: 58 ENNVFLDQSQVKADGFQKLLEFIYTGTLNL-DSWNVKEIHQAADYLKVEEVVTKCKIKME 116
Query: 171 ARA-LAEADSTK 181
A +A ST+
Sbjct: 117 DFAFIANPSSTE 128
Score = 55.5 bits (132), Expect = 1e-07
Identities = 22/54 (40%), Positives = 33/54 (61%)
Query: 467 FTEDVPTCKTCGKTFSCSYTLRRHATVHTRERPYECRYCLRSYTQSGDLYRHIR 520
+++ P C TCGK FS + +LRRH +H +PY C C +++TQ L H+R
Sbjct: 297 YSKAKPMCNTCGKVFSEASSLRRHMRIHKGVKPYVCHLCGKAFTQCNQLKTHVR 350
Score = 53.1 bits (126), Expect = 7e-07
Identities = 23/52 (44%), Positives = 31/52 (59%)
Query: 474 CKTCGKTFSCSYTLRRHATVHTRERPYECRYCLRSYTQSGDLYRHIRKAHNE 525
C TCGK F+ S +L H+ HT E+PY C C +S+ SG+L +H R E
Sbjct: 445 CDTCGKAFAVSSSLITHSRKHTGEKPYICGICGKSFISSGELNKHFRSHTGE 496
Score = 50.8 bits (120), Expect = 3e-06
Identities = 30/86 (34%), Positives = 40/86 (46%), Gaps = 2/86 (2%)
Query: 474 CKTCGKTFSCSYTLRRHATVHTRERPYECRYCLRSYTQSGDLYRHIRKAHN--EDLAKRS 531
C CGK+F S L +H HT ERP+ C C SYT +L +H K H+ + S
Sbjct: 473 CGICGKSFISSGELNKHFRSHTGERPFICELCGNSYTDIKNLKKHKTKVHSGADKTLDSS 532
Query: 532 KPDPEVGPLLGVQPLPGSPTADRQSS 557
D + +Q P S T D + S
Sbjct: 533 AEDHTLSEQDSIQKSPLSETMDVKPS 558
Score = 48.9 bits (115), Expect = 1e-05
Identities = 20/53 (37%), Positives = 27/53 (50%)
Query: 474 CKTCGKTFSCSYTLRRHATVHTRERPYECRYCLRSYTQSGDLYRHIRKAHNED 526
C CGK F+ L+ H HT E+PY+C C + + Q L H R H E+
Sbjct: 332 CHLCGKAFTQCNQLKTHVRTHTGEKPYKCELCDKGFAQKCQLVFHSRMHHGEE 384
Score = 43.9 bits (102), Expect = 4e-04
Identities = 20/52 (38%), Positives = 27/52 (51%)
Query: 474 CKTCGKTFSCSYTLRRHATVHTRERPYECRYCLRSYTQSGDLYRHIRKAHNE 525
C CG+ F+ + TL H HT E+PY C C +++ S L H RK E
Sbjct: 417 CDRCGQRFAQASTLTYHVRRHTGEKPYVCDTCGKAFAVSSSLITHSRKHTGE 468
Score = 42.0 bits (97), Expect = 0.002
Identities = 18/52 (34%), Positives = 27/52 (51%)
Query: 474 CKTCGKTFSCSYTLRRHATVHTRERPYECRYCLRSYTQSGDLYRHIRKAHNE 525
C C F+ S L+ HA H+ E+PY C C + + Q+ L H+R+ E
Sbjct: 389 CDVCNLQFATSSNLKIHARKHSGEKPYVCDRCGQRFAQASTLTYHVRRHTGE 440
Score = 35.0 bits (79), Expect = 0.19
Identities = 18/53 (33%), Positives = 26/53 (49%), Gaps = 1/53 (1%)
Query: 474 CKTCGKTFSCSYTLRRHATVHT-RERPYECRYCLRSYTQSGDLYRHIRKAHNE 525
C+ C K F+ L H+ +H E+PY+C C + S +L H RK E
Sbjct: 360 CELCDKGFAQKCQLVFHSRMHHGEEKPYKCDVCNLQFATSSNLKIHARKHSGE 412
>gi|84872173 zinc finger protein 131 [Homo sapiens]
Length = 589
Score = 85.9 bits (211), Expect = 9e-17
Identities = 59/162 (36%), Positives = 86/162 (53%), Gaps = 11/162 (6%)
Query: 52 EFPEHSQQLLQSLREQRSQGFLCDCTVMVGSTQFLAHRAVLASCSPFFQLFYKERELDKR 111
EFPEH + +L L EQR Q D T++V F AH+AVLA+CS FF F+ +E +
Sbjct: 12 EFPEHHKMILDRLNEQREQDRFTDITLIVDGHHFKAHKAVLAACSKFFYKFF--QEFTQE 69
Query: 112 DLVCIHNEIVTAPAFGLLLDFMYAGQLTLRGDTPVEDVLAAASYLHMNDIVKVCK-RRLQ 170
LV I E V+ AF L++F Y +L ++G+ DV AA +L M + +K + R +
Sbjct: 70 PLVEI--EGVSKMAFRHLIEFTYTAKLMIQGEEEANDVWKAAEFLQMLEAIKALEVRNKE 127
Query: 171 ARALAEADSTKKEEETNSQLPSLEFLSSTSRGTQPSLASAET 212
A E ++T K E + ++ TS SL SAE+
Sbjct: 128 NSAPLEENTTGKNEAKKRK------IAETSNVITESLPSAES 163
Score = 42.0 bits (97), Expect = 0.002
Identities = 16/51 (31%), Positives = 25/51 (49%)
Query: 474 CKTCGKTFSCSYTLRRHATVHTRERPYECRYCLRSYTQSGDLYRHIRKAHN 524
C+ C F+ + H +HT ++P C C + Q +L RH+ AHN
Sbjct: 360 CQVCNSVFNSWDQFKDHLVIHTGDKPNHCTLCDLWFMQGNELRRHLSDAHN 410
Score = 35.4 bits (80), Expect = 0.14
Identities = 16/62 (25%), Positives = 27/62 (43%)
Query: 471 VPTCKTCGKTFSCSYTLRRHATVHTRERPYECRYCLRSYTQSGDLYRHIRKAHNEDLAKR 530
+ C+ C K F + H HT E+P+EC C + ++ L H+ AK+
Sbjct: 293 IHVCQYCEKQFDHFGHFKEHLRKHTGEKPFECPNCHERFARNSTLKCHLTACQTGVGAKK 352
Query: 531 SK 532
+
Sbjct: 353 GR 354
>gi|21040324 B-cell lymphoma 6 protein isoform 1 [Homo sapiens]
Length = 706
Score = 82.4 bits (202), Expect = 1e-15
Identities = 128/585 (21%), Positives = 208/585 (35%), Gaps = 136/585 (23%)
Query: 46 PSWGTMEFPEHSQQLLQSLREQRSQGFLCDCTVMVGSTQFLAHRAVLASCSPFFQLFYKE 105
P+ ++F H+ +L +L RS+ L D ++V QF AH+ VL +CS F + +
Sbjct: 4 PADSCIQFTRHASDVLLNLNRLRSRDILTDVVIVVSREQFRAHKTVLMACSGLFYSIFTD 63
Query: 106 RELDKRDLVCIHNEIVTAPAFGLLLDFMYAGQLTLRGDTPVEDVLAAASYLHMNDIVKVC 165
+ ++ + EI F +LLDFMY +L LR + + V+A A YL M +V C
Sbjct: 64 QLKCNLSVINLDPEI-NPEGFCILLDFMYTSRLNLR-EGNIMAVMATAMYLQMEHVVDTC 121
Query: 166 KRRLQA--RALAEADSTKKEEETNSQ-LPSLEFLSSTSRGTQPS---LASAE--TSGHWG 217
++ ++A + A +EE NS+ L + ++ R + L SA S +
Sbjct: 122 RKFIKASEAEMVSAIKPPREEFLNSRMLMPQDIMAYRGREVVENNLPLRSAPGCESRAFA 181
Query: 218 KGEWKGSAAPSPTVRPPDEPPMSSGADTTQPGMEVDAPHLRAPHPPVADVSLASPSSSTE 277
+ G + P + P+SS + + +V P + P P A P S
Sbjct: 182 PSLYSGLSTPPASYSMYSHLPVSSLLFSDEEFRDVRMP-VANPFPK----ERALPCDSAR 236
Query: 278 TIPTNYFSSGISAVSLEPLPSLDVGPE--SLRVVEPKDP----------GGPLQGFYPPA 325
+P Y P+L+V P + PK+ +G P A
Sbjct: 237 PVPGEY-----------SRPTLEVSPNVCHSNIYSPKETIPEEARSDMHYSVAEGLKPAA 285
Query: 326 SAPTSAPAPVSAPVPSQAPAPAEAELVQVKVEAI--------VISDEETDVSDEQPQGPE 377
+ +AP + P+ + + + E ++S + SD QP P
Sbjct: 286 PSARNAPYFPCDKASKEEERPSSEDEIALHFEPPNAPLNRKGLVSPQSPQKSDCQPNSPT 345
Query: 378 RAFPS--------GGAVYGAQPSQPEAF-------------------EDPGAAGLEEVGP 410
+ S G+ P+ P+A E P A L + P
Sbjct: 346 ESCSSKNACILQASGSPPAKSPTDPKACNWKKYKFIVLNSLNQNAKPEGPEQAELGRLSP 405
Query: 411 SDHFLP---TDPHLPYHL-------LPGAGQ-------------YHRGLVTSPLPAPASL 447
+ P P P +L L +G+ +R + SP + S
Sbjct: 406 RAYTAPPACQPPMEPENLDLQSPTKLSASGEDSTIPQASRLNNIVNRSMTGSPRSSSES- 464
Query: 448 HEPLYL----------------------------------SSEYEAAPGSFGVFTEDVPT 473
H PLY+ SEY + G F
Sbjct: 465 HSPLYMHPPKCTSCGSQSPQHAEMCLHTAGPTFPEEMGETQSEYSDSSCENGAF-----F 519
Query: 474 CKTCGKTFSCSYTLRRHATVHTRERPYECRYCLRSYTQSGDLYRH 518
C C FS +L+RH ++PY+C C S+ G+L H
Sbjct: 520 CNECDCRFSEEASLKRHTLQTHSDKPYKCDRCQASFRYKGNLASH 564
Score = 45.8 bits (107), Expect = 1e-04
Identities = 18/50 (36%), Positives = 25/50 (50%)
Query: 474 CKTCGKTFSCSYTLRRHATVHTRERPYECRYCLRSYTQSGDLYRHIRKAH 523
C+ CG F TL+ H +HT E+PY C C + L H+R+ H
Sbjct: 632 CEICGTRFRHLQTLKSHLRIHTGEKPYHCEKCNLHFRHKSQLRLHLRQKH 681
Score = 41.6 bits (96), Expect = 0.002
Identities = 18/47 (38%), Positives = 23/47 (48%)
Query: 474 CKTCGKTFSCSYTLRRHATVHTRERPYECRYCLRSYTQSGDLYRHIR 520
C+TCG F LR H +HT E+PY C C + L H+R
Sbjct: 604 CETCGARFVQVAHLRAHVLIHTGEKPYPCEICGTRFRHLQTLKSHLR 650
Score = 40.4 bits (93), Expect = 0.004
Identities = 17/47 (36%), Positives = 22/47 (46%)
Query: 474 CKTCGKTFSCSYTLRRHATVHTRERPYECRYCLRSYTQSGDLYRHIR 520
C C +F L H TVHT E+PY C C + + +L H R
Sbjct: 548 CDRCQASFRYKGNLASHKTVHTGEKPYRCNICGAQFNRPANLKTHTR 594
Score = 40.4 bits (93), Expect = 0.004
Identities = 15/46 (32%), Positives = 23/46 (50%)
Query: 474 CKTCGKTFSCSYTLRRHATVHTRERPYECRYCLRSYTQSGDLYRHI 519
C CG F+ L+ H +H+ E+PY+C C + Q L H+
Sbjct: 576 CNICGAQFNRPANLKTHTRIHSGEKPYKCETCGARFVQVAHLRAHV 621
>gi|195927002 B-cell lymphoma 6 protein isoform 1 [Homo sapiens]
Length = 706
Score = 82.4 bits (202), Expect = 1e-15
Identities = 128/585 (21%), Positives = 208/585 (35%), Gaps = 136/585 (23%)
Query: 46 PSWGTMEFPEHSQQLLQSLREQRSQGFLCDCTVMVGSTQFLAHRAVLASCSPFFQLFYKE 105
P+ ++F H+ +L +L RS+ L D ++V QF AH+ VL +CS F + +
Sbjct: 4 PADSCIQFTRHASDVLLNLNRLRSRDILTDVVIVVSREQFRAHKTVLMACSGLFYSIFTD 63
Query: 106 RELDKRDLVCIHNEIVTAPAFGLLLDFMYAGQLTLRGDTPVEDVLAAASYLHMNDIVKVC 165
+ ++ + EI F +LLDFMY +L LR + + V+A A YL M +V C
Sbjct: 64 QLKCNLSVINLDPEI-NPEGFCILLDFMYTSRLNLR-EGNIMAVMATAMYLQMEHVVDTC 121
Query: 166 KRRLQA--RALAEADSTKKEEETNSQ-LPSLEFLSSTSRGTQPS---LASAE--TSGHWG 217
++ ++A + A +EE NS+ L + ++ R + L SA S +
Sbjct: 122 RKFIKASEAEMVSAIKPPREEFLNSRMLMPQDIMAYRGREVVENNLPLRSAPGCESRAFA 181
Query: 218 KGEWKGSAAPSPTVRPPDEPPMSSGADTTQPGMEVDAPHLRAPHPPVADVSLASPSSSTE 277
+ G + P + P+SS + + +V P + P P A P S
Sbjct: 182 PSLYSGLSTPPASYSMYSHLPVSSLLFSDEEFRDVRMP-VANPFPK----ERALPCDSAR 236
Query: 278 TIPTNYFSSGISAVSLEPLPSLDVGPE--SLRVVEPKDP----------GGPLQGFYPPA 325
+P Y P+L+V P + PK+ +G P A
Sbjct: 237 PVPGEY-----------SRPTLEVSPNVCHSNIYSPKETIPEEARSDMHYSVAEGLKPAA 285
Query: 326 SAPTSAPAPVSAPVPSQAPAPAEAELVQVKVEAI--------VISDEETDVSDEQPQGPE 377
+ +AP + P+ + + + E ++S + SD QP P
Sbjct: 286 PSARNAPYFPCDKASKEEERPSSEDEIALHFEPPNAPLNRKGLVSPQSPQKSDCQPNSPT 345
Query: 378 RAFPS--------GGAVYGAQPSQPEAF-------------------EDPGAAGLEEVGP 410
+ S G+ P+ P+A E P A L + P
Sbjct: 346 ESCSSKNACILQASGSPPAKSPTDPKACNWKKYKFIVLNSLNQNAKPEGPEQAELGRLSP 405
Query: 411 SDHFLP---TDPHLPYHL-------LPGAGQ-------------YHRGLVTSPLPAPASL 447
+ P P P +L L +G+ +R + SP + S
Sbjct: 406 RAYTAPPACQPPMEPENLDLQSPTKLSASGEDSTIPQASRLNNIVNRSMTGSPRSSSES- 464
Query: 448 HEPLYL----------------------------------SSEYEAAPGSFGVFTEDVPT 473
H PLY+ SEY + G F
Sbjct: 465 HSPLYMHPPKCTSCGSQSPQHAEMCLHTAGPTFPEEMGETQSEYSDSSCENGAF-----F 519
Query: 474 CKTCGKTFSCSYTLRRHATVHTRERPYECRYCLRSYTQSGDLYRH 518
C C FS +L+RH ++PY+C C S+ G+L H
Sbjct: 520 CNECDCRFSEEASLKRHTLQTHSDKPYKCDRCQASFRYKGNLASH 564
Score = 45.8 bits (107), Expect = 1e-04
Identities = 18/50 (36%), Positives = 25/50 (50%)
Query: 474 CKTCGKTFSCSYTLRRHATVHTRERPYECRYCLRSYTQSGDLYRHIRKAH 523
C+ CG F TL+ H +HT E+PY C C + L H+R+ H
Sbjct: 632 CEICGTRFRHLQTLKSHLRIHTGEKPYHCEKCNLHFRHKSQLRLHLRQKH 681
Score = 41.6 bits (96), Expect = 0.002
Identities = 18/47 (38%), Positives = 23/47 (48%)
Query: 474 CKTCGKTFSCSYTLRRHATVHTRERPYECRYCLRSYTQSGDLYRHIR 520
C+TCG F LR H +HT E+PY C C + L H+R
Sbjct: 604 CETCGARFVQVAHLRAHVLIHTGEKPYPCEICGTRFRHLQTLKSHLR 650
Score = 40.4 bits (93), Expect = 0.004
Identities = 17/47 (36%), Positives = 22/47 (46%)
Query: 474 CKTCGKTFSCSYTLRRHATVHTRERPYECRYCLRSYTQSGDLYRHIR 520
C C +F L H TVHT E+PY C C + + +L H R
Sbjct: 548 CDRCQASFRYKGNLASHKTVHTGEKPYRCNICGAQFNRPANLKTHTR 594
Score = 40.4 bits (93), Expect = 0.004
Identities = 15/46 (32%), Positives = 23/46 (50%)
Query: 474 CKTCGKTFSCSYTLRRHATVHTRERPYECRYCLRSYTQSGDLYRHI 519
C CG F+ L+ H +H+ E+PY+C C + Q L H+
Sbjct: 576 CNICGAQFNRPANLKTHTRIHSGEKPYKCETCGARFVQVAHLRAHV 621
>gi|223890203 zinc finger and BTB domain containing 22 [Homo
sapiens]
Length = 634
Score = 81.3 bits (199), Expect = 2e-15
Identities = 119/524 (22%), Positives = 180/524 (34%), Gaps = 78/524 (14%)
Query: 51 MEFPEHSQQLLQSLREQRSQGFLCDCTVMVGSTQFLAHRAVLASCSPFFQLFYKERELDK 110
+ FPE + LL+SL +QR QG LCD ++ V +F AHRAVLA+ SP+F ++ L K
Sbjct: 34 VSFPEVTSALLESLNQQRLQGQLCDVSIRVQGREFRAHRAVLAASSPYFH----DQVLLK 89
Query: 111 RDLVCIHNEIVTAPAFGLLLDFMYAGQLTLRGDTPVEDVLAAASYLHMNDIVKVCKRRLQ 170
++ AF +L Y G+L++ + + L S L M IV C L+
Sbjct: 90 GMTSISLPSVMDPGAFETVLASAYTGRLSMAA-ADIVNFLTVGSVLQMWHIVDKCTELLR 148
Query: 171 ARALAEADSTKKEEETNSQLPSLEFLSSTSRGTQPSLASAETSGHWGKGEWKGSAAPSPT 230
+ + T+ +P S + P+ + S + S + S
Sbjct: 149 EGRASATTTITTAAATSVTVPGAGVPSGSGGTVAPATMGSARSHASSRASENQSPSSSNY 208
Query: 231 VRPPDEPPMSSGADTTQPGMEVDAPHLRAPHPPVADVSLASPSSSTETIPTNYFSSGISA 290
P + SS + V + R P + S +++
Sbjct: 209 FSPRESTDFSSSSQEAFAASAVGSGERRGGGPVFPAPVVGSGGATS------------GK 256
Query: 291 VSLEPLPSLDVGPESLRVVEPKDPGGPLQGFYPPASAP--------TSAPAPVSAPVPSQ 342
+ LE D G + V P G + PP+ P P P+ Q
Sbjct: 257 LLLEADELCDDGGDGRGAVVP-GAGLRRPTYTPPSIMPQKHWVYVKRGGNCPAPTPLVPQ 315
Query: 343 APAPAEAELVQVKVEAIVISDEETDVSDEQPQGPERAFPSGGAVYGAQPSQPEAFEDPGA 402
P E E + E +V++ E D DE+ G R GG S +P
Sbjct: 316 DPDLEEEE----EEEDLVLTCE--DDEDEELGGSSRVPVGGGPEATLSISDVRTLSEPPD 369
Query: 403 AGLEEV-------------------GPSDHFLPT-----DPHLPYHLLPGAGQYHRGLVT 438
G E+V G D PT H P LLP Q ++ LV
Sbjct: 370 KGEEQVNFCESSNDFGPYEGGGPVAGLDDSGGPTPSSYAPSHPPRPLLPLDMQGNQILVF 429
Query: 439 SPLPAPASLHEP----------------------LYLSSEYEAAPGSFGVFTEDVPTCKT 476
+ +S P L + PG G +
Sbjct: 430 PSSSSSSSSQAPGQPPGNQAEHGAVTVGGTSVGSLGVPGSVGGVPGGTGSGDGNKIFLCH 489
Query: 477 CGKTFSCSYTLRRHATVHTRERPYECRYCLRSYTQSGDLYRHIR 520
CGK FS RH +H RP++C C + + L H++
Sbjct: 490 CGKAFSHKSMRDRHVNMHLNLRPFDCPVCNKKFKMKHHLTEHMK 533
Score = 43.1 bits (100), Expect = 7e-04
Identities = 28/97 (28%), Positives = 38/97 (39%), Gaps = 15/97 (15%)
Query: 474 CKTCGKTFSCSYTLRRHATVHTRERPYECRYCLRSYTQSGDLYRHIRKAHNEDLAKRSKP 533
C C K F + L H HT +PYEC C + + RH + H E +
Sbjct: 515 CPVCNKKFKMKHHLTEHMKTHTGLKPYECGVCAKKFMWRDSFMRH--RGHCERRHRLGG- 571
Query: 534 DPEVGPLLGVQPLPGSPT-----ADRQSSSGGGPPKD 565
+G P PG+PT + R+S GG D
Sbjct: 572 -------VGAVPGPGTPTGPSLPSKRESPGVGGGSGD 601
>gi|223890199 zinc finger and BTB domain containing 22 [Homo
sapiens]
Length = 634
Score = 81.3 bits (199), Expect = 2e-15
Identities = 119/524 (22%), Positives = 180/524 (34%), Gaps = 78/524 (14%)
Query: 51 MEFPEHSQQLLQSLREQRSQGFLCDCTVMVGSTQFLAHRAVLASCSPFFQLFYKERELDK 110
+ FPE + LL+SL +QR QG LCD ++ V +F AHRAVLA+ SP+F ++ L K
Sbjct: 34 VSFPEVTSALLESLNQQRLQGQLCDVSIRVQGREFRAHRAVLAASSPYFH----DQVLLK 89
Query: 111 RDLVCIHNEIVTAPAFGLLLDFMYAGQLTLRGDTPVEDVLAAASYLHMNDIVKVCKRRLQ 170
++ AF +L Y G+L++ + + L S L M IV C L+
Sbjct: 90 GMTSISLPSVMDPGAFETVLASAYTGRLSMAA-ADIVNFLTVGSVLQMWHIVDKCTELLR 148
Query: 171 ARALAEADSTKKEEETNSQLPSLEFLSSTSRGTQPSLASAETSGHWGKGEWKGSAAPSPT 230
+ + T+ +P S + P+ + S + S + S
Sbjct: 149 EGRASATTTITTAAATSVTVPGAGVPSGSGGTVAPATMGSARSHASSRASENQSPSSSNY 208
Query: 231 VRPPDEPPMSSGADTTQPGMEVDAPHLRAPHPPVADVSLASPSSSTETIPTNYFSSGISA 290
P + SS + V + R P + S +++
Sbjct: 209 FSPRESTDFSSSSQEAFAASAVGSGERRGGGPVFPAPVVGSGGATS------------GK 256
Query: 291 VSLEPLPSLDVGPESLRVVEPKDPGGPLQGFYPPASAP--------TSAPAPVSAPVPSQ 342
+ LE D G + V P G + PP+ P P P+ Q
Sbjct: 257 LLLEADELCDDGGDGRGAVVP-GAGLRRPTYTPPSIMPQKHWVYVKRGGNCPAPTPLVPQ 315
Query: 343 APAPAEAELVQVKVEAIVISDEETDVSDEQPQGPERAFPSGGAVYGAQPSQPEAFEDPGA 402
P E E + E +V++ E D DE+ G R GG S +P
Sbjct: 316 DPDLEEEE----EEEDLVLTCE--DDEDEELGGSSRVPVGGGPEATLSISDVRTLSEPPD 369
Query: 403 AGLEEV-------------------GPSDHFLPT-----DPHLPYHLLPGAGQYHRGLVT 438
G E+V G D PT H P LLP Q ++ LV
Sbjct: 370 KGEEQVNFCESSNDFGPYEGGGPVAGLDDSGGPTPSSYAPSHPPRPLLPLDMQGNQILVF 429
Query: 439 SPLPAPASLHEP----------------------LYLSSEYEAAPGSFGVFTEDVPTCKT 476
+ +S P L + PG G +
Sbjct: 430 PSSSSSSSSQAPGQPPGNQAEHGAVTVGGTSVGSLGVPGSVGGVPGGTGSGDGNKIFLCH 489
Query: 477 CGKTFSCSYTLRRHATVHTRERPYECRYCLRSYTQSGDLYRHIR 520
CGK FS RH +H RP++C C + + L H++
Sbjct: 490 CGKAFSHKSMRDRHVNMHLNLRPFDCPVCNKKFKMKHHLTEHMK 533
Score = 43.1 bits (100), Expect = 7e-04
Identities = 28/97 (28%), Positives = 38/97 (39%), Gaps = 15/97 (15%)
Query: 474 CKTCGKTFSCSYTLRRHATVHTRERPYECRYCLRSYTQSGDLYRHIRKAHNEDLAKRSKP 533
C C K F + L H HT +PYEC C + + RH + H E +
Sbjct: 515 CPVCNKKFKMKHHLTEHMKTHTGLKPYECGVCAKKFMWRDSFMRH--RGHCERRHRLGG- 571
Query: 534 DPEVGPLLGVQPLPGSPT-----ADRQSSSGGGPPKD 565
+G P PG+PT + R+S GG D
Sbjct: 572 -------VGAVPGPGTPTGPSLPSKRESPGVGGGSGD 601
>gi|139394579 zinc finger and BTB domain containing 40 [Homo
sapiens]
Length = 1239
Score = 81.3 bits (199), Expect = 2e-15
Identities = 70/240 (29%), Positives = 105/240 (43%), Gaps = 25/240 (10%)
Query: 51 MEFPEHSQQLLQSLREQRSQGFLCDCTVMVGSTQFLAHRAVLASCSPFFQLFYKERELDK 110
ME P +S+QLLQ L + CDCT+ +G+ F AH+ VLA+ S F+ LD
Sbjct: 1 MELPNYSRQLLQQLYTLCKEQQFCDCTISIGTIYFRAHKLVLAAASLLFKTL-----LDN 55
Query: 111 RDLVCIHNEIVTAPAFGLLLDFMYAGQLTLRGDTPVEDVLAAASYLHMNDIVKVCKRRL- 169
D + I +V+ F LLL+ MY G+L + G +++ A L M D+ CK L
Sbjct: 56 TDTISIDASVVSPEEFALLLEMMYTGKLPV-GKHNFSKIISLADSLQMFDVAVSCKNLLT 114
Query: 170 -------QARALAEADSTKKEE-ETNSQLPSLEFLSSTSRG---TQPSLASAETSGHWGK 218
Q + + + + E + P +E LSS G + P LA+ T G K
Sbjct: 115 SLVNCSVQGQVVRDVSAPSSETFRKEPEKPQVEILSSEGAGEPHSSPELAA--TPGGPVK 172
Query: 219 GEWKGSA---APSPTVRPPDEPPMSSGADTTQPGMEVDAPHLRAPHPPVADVSLASPSSS 275
E + +A + +V P A+T P +P P V S A +S+
Sbjct: 173 AETEEAAHSVSQEMSVNSPTAQESQRNAET--PAETPTTAEACSPSPAVQTFSEAKKTST 230
Score = 58.9 bits (141), Expect = 1e-08
Identities = 23/59 (38%), Positives = 38/59 (64%)
Query: 467 FTEDVPTCKTCGKTFSCSYTLRRHATVHTRERPYECRYCLRSYTQSGDLYRHIRKAHNE 525
F E +C+ CG F+ + TL+ H +HT +RP+ C++CL ++TQ+ L H +K H+E
Sbjct: 831 FDEKPFSCEECGAKFAANSTLKNHLRLHTGDRPFMCKHCLMTFTQASALAYHTKKKHSE 889
Score = 50.1 bits (118), Expect = 6e-06
Identities = 22/66 (33%), Positives = 33/66 (50%)
Query: 466 VFTEDVPTCKTCGKTFSCSYTLRRHATVHTRERPYECRYCLRSYTQSGDLYRHIRKAHNE 525
V +++ C TCGK FS L RH H +P+ C C ++Y Q L+ H R H +
Sbjct: 972 VHSKEYHPCPTCGKIFSAPSMLERHVVTHVGGKPFSCGICNKAYQQLSGLWYHNRTHHPD 1031
Query: 526 DLAKRS 531
A ++
Sbjct: 1032 VFAAQN 1037
Score = 46.2 bits (108), Expect = 8e-05
Identities = 19/51 (37%), Positives = 27/51 (52%)
Query: 474 CKTCGKTFSCSYTLRRHATVHTRERPYECRYCLRSYTQSGDLYRHIRKAHN 524
C+ C F+ S L RH HT ++PY CR C + + Q+ L H+ HN
Sbjct: 895 CQYCDAVFAQSIELSRHVRTHTGDKPYVCRDCGKGFRQANGLSIHLHTFHN 945
Score = 41.6 bits (96), Expect = 0.002
Identities = 22/61 (36%), Positives = 32/61 (52%), Gaps = 2/61 (3%)
Query: 468 TEDVP-TCKTCGKTFSCSYTLRRHA-TVHTRERPYECRYCLRSYTQSGDLYRHIRKAHNE 525
T D P C+ CGK F + L H T H E PY+C+ C S+ D +HI + H++
Sbjct: 916 TGDKPYVCRDCGKGFRQANGLSIHLHTFHNIEDPYDCKKCRMSFPTLQDHRKHIHEVHSK 975
Query: 526 D 526
+
Sbjct: 976 E 976
Score = 35.0 bits (79), Expect = 0.19
Identities = 15/49 (30%), Positives = 25/49 (51%), Gaps = 1/49 (2%)
Query: 473 TCKTCGKTFSCSYTLRRHA-TVHTRERPYECRYCLRSYTQSGDLYRHIR 520
TC CG+ F+ + ++ H T H E+P+ C C + + L H+R
Sbjct: 808 TCDLCGREFAHASGMQYHKLTEHFDEKPFSCEECGAKFAANSTLKNHLR 856
Score = 32.0 bits (71), Expect = 1.6
Identities = 14/51 (27%), Positives = 22/51 (43%), Gaps = 1/51 (1%)
Query: 474 CKTCGKTFSCSYTLRRHATV-HTRERPYECRYCLRSYTQSGDLYRHIRKAH 523
C C + F L+ H H+ +P+ C YC ++ G L H+ H
Sbjct: 1077 CDQCKELFPTPALLQVHVKCQHSGSQPFRCLYCAATFRFPGALQHHVTTEH 1127
>gi|139394556 zinc finger and BTB domain containing 40 [Homo
sapiens]
Length = 1239
Score = 81.3 bits (199), Expect = 2e-15
Identities = 70/240 (29%), Positives = 105/240 (43%), Gaps = 25/240 (10%)
Query: 51 MEFPEHSQQLLQSLREQRSQGFLCDCTVMVGSTQFLAHRAVLASCSPFFQLFYKERELDK 110
ME P +S+QLLQ L + CDCT+ +G+ F AH+ VLA+ S F+ LD
Sbjct: 1 MELPNYSRQLLQQLYTLCKEQQFCDCTISIGTIYFRAHKLVLAAASLLFKTL-----LDN 55
Query: 111 RDLVCIHNEIVTAPAFGLLLDFMYAGQLTLRGDTPVEDVLAAASYLHMNDIVKVCKRRL- 169
D + I +V+ F LLL+ MY G+L + G +++ A L M D+ CK L
Sbjct: 56 TDTISIDASVVSPEEFALLLEMMYTGKLPV-GKHNFSKIISLADSLQMFDVAVSCKNLLT 114
Query: 170 -------QARALAEADSTKKEE-ETNSQLPSLEFLSSTSRG---TQPSLASAETSGHWGK 218
Q + + + + E + P +E LSS G + P LA+ T G K
Sbjct: 115 SLVNCSVQGQVVRDVSAPSSETFRKEPEKPQVEILSSEGAGEPHSSPELAA--TPGGPVK 172
Query: 219 GEWKGSA---APSPTVRPPDEPPMSSGADTTQPGMEVDAPHLRAPHPPVADVSLASPSSS 275
E + +A + +V P A+T P +P P V S A +S+
Sbjct: 173 AETEEAAHSVSQEMSVNSPTAQESQRNAET--PAETPTTAEACSPSPAVQTFSEAKKTST 230
Score = 58.9 bits (141), Expect = 1e-08
Identities = 23/59 (38%), Positives = 38/59 (64%)
Query: 467 FTEDVPTCKTCGKTFSCSYTLRRHATVHTRERPYECRYCLRSYTQSGDLYRHIRKAHNE 525
F E +C+ CG F+ + TL+ H +HT +RP+ C++CL ++TQ+ L H +K H+E
Sbjct: 831 FDEKPFSCEECGAKFAANSTLKNHLRLHTGDRPFMCKHCLMTFTQASALAYHTKKKHSE 889
Score = 50.1 bits (118), Expect = 6e-06
Identities = 22/66 (33%), Positives = 33/66 (50%)
Query: 466 VFTEDVPTCKTCGKTFSCSYTLRRHATVHTRERPYECRYCLRSYTQSGDLYRHIRKAHNE 525
V +++ C TCGK FS L RH H +P+ C C ++Y Q L+ H R H +
Sbjct: 972 VHSKEYHPCPTCGKIFSAPSMLERHVVTHVGGKPFSCGICNKAYQQLSGLWYHNRTHHPD 1031
Query: 526 DLAKRS 531
A ++
Sbjct: 1032 VFAAQN 1037
Score = 46.2 bits (108), Expect = 8e-05
Identities = 19/51 (37%), Positives = 27/51 (52%)
Query: 474 CKTCGKTFSCSYTLRRHATVHTRERPYECRYCLRSYTQSGDLYRHIRKAHN 524
C+ C F+ S L RH HT ++PY CR C + + Q+ L H+ HN
Sbjct: 895 CQYCDAVFAQSIELSRHVRTHTGDKPYVCRDCGKGFRQANGLSIHLHTFHN 945
Score = 41.6 bits (96), Expect = 0.002
Identities = 22/61 (36%), Positives = 32/61 (52%), Gaps = 2/61 (3%)
Query: 468 TEDVP-TCKTCGKTFSCSYTLRRHA-TVHTRERPYECRYCLRSYTQSGDLYRHIRKAHNE 525
T D P C+ CGK F + L H T H E PY+C+ C S+ D +HI + H++
Sbjct: 916 TGDKPYVCRDCGKGFRQANGLSIHLHTFHNIEDPYDCKKCRMSFPTLQDHRKHIHEVHSK 975
Query: 526 D 526
+
Sbjct: 976 E 976
Score = 35.0 bits (79), Expect = 0.19
Identities = 15/49 (30%), Positives = 25/49 (51%), Gaps = 1/49 (2%)
Query: 473 TCKTCGKTFSCSYTLRRHA-TVHTRERPYECRYCLRSYTQSGDLYRHIR 520
TC CG+ F+ + ++ H T H E+P+ C C + + L H+R
Sbjct: 808 TCDLCGREFAHASGMQYHKLTEHFDEKPFSCEECGAKFAANSTLKNHLR 856
Score = 32.0 bits (71), Expect = 1.6
Identities = 14/51 (27%), Positives = 22/51 (43%), Gaps = 1/51 (1%)
Query: 474 CKTCGKTFSCSYTLRRHATV-HTRERPYECRYCLRSYTQSGDLYRHIRKAH 523
C C + F L+ H H+ +P+ C YC ++ G L H+ H
Sbjct: 1077 CDQCKELFPTPALLQVHVKCQHSGSQPFRCLYCAATFRFPGALQHHVTTEH 1127
>gi|182509180 zinc finger and BTB domain containing 1 isoform 1
[Homo sapiens]
Length = 713
Score = 80.1 bits (196), Expect = 5e-15
Identities = 44/140 (31%), Positives = 72/140 (51%), Gaps = 2/140 (1%)
Query: 51 MEFPEHSQQLLQSLREQRSQGFLCDCTVMVGSTQFLAHRAVLASCSPFFQLFYKERELDK 110
M P HS +LQ L QR GFLCDC + + F AH+AVLA+CS +F++F+ +
Sbjct: 1 MAKPSHSSYVLQQLNNQREWGFLCDCCIAIDDIYFQAHKAVLAACSSYFRMFFMNHQHST 60
Query: 111 RDLVCIHNEIVTAPAFGLLLDFMYAGQLTLRGDTPVEDVLAAASYLHMNDIVKVCKRRLQ 170
L + N ++A F L+L FMY G++ + + E A +YL + ++ +
Sbjct: 61 AQL-NLSNMKISAECFDLILQFMYLGKI-MTAPSSFEQFKVAMNYLQLYNVPDCLEDIQD 118
Query: 171 ARALAEADSTKKEEETNSQL 190
A + S+ + NS++
Sbjct: 119 ADCSSSKCSSSASSKQNSKM 138
Score = 40.0 bits (92), Expect = 0.006
Identities = 17/45 (37%), Positives = 24/45 (53%)
Query: 474 CKTCGKTFSCSYTLRRHATVHTRERPYECRYCLRSYTQSGDLYRH 518
C CGK F LR H TVHT+E+ + C+ C + + + L H
Sbjct: 580 CNLCGKGFYQRCHLREHYTVHTKEKQFVCQTCGKQFLRERQLRLH 624
Score = 33.1 bits (74), Expect = 0.71
Identities = 16/46 (34%), Positives = 21/46 (45%)
Query: 474 CKTCGKTFSCSYTLRRHATVHTRERPYECRYCLRSYTQSGDLYRHI 519
C+TCGK F LR H +H Y C C + + D RH+
Sbjct: 608 CQTCGKQFLRERQLRLHNDMHKGMARYVCSICDQGNFRKHDHVRHM 653
>gi|182509178 zinc finger and BTB domain containing 1 isoform 2
[Homo sapiens]
Length = 644
Score = 80.1 bits (196), Expect = 5e-15
Identities = 44/140 (31%), Positives = 72/140 (51%), Gaps = 2/140 (1%)
Query: 51 MEFPEHSQQLLQSLREQRSQGFLCDCTVMVGSTQFLAHRAVLASCSPFFQLFYKERELDK 110
M P HS +LQ L QR GFLCDC + + F AH+AVLA+CS +F++F+ +
Sbjct: 1 MAKPSHSSYVLQQLNNQREWGFLCDCCIAIDDIYFQAHKAVLAACSSYFRMFFMNHQHST 60
Query: 111 RDLVCIHNEIVTAPAFGLLLDFMYAGQLTLRGDTPVEDVLAAASYLHMNDIVKVCKRRLQ 170
L + N ++A F L+L FMY G++ + + E A +YL + ++ +
Sbjct: 61 AQL-NLSNMKISAECFDLILQFMYLGKI-MTAPSSFEQFKVAMNYLQLYNVPDCLEDIQD 118
Query: 171 ARALAEADSTKKEEETNSQL 190
A + S+ + NS++
Sbjct: 119 ADCSSSKCSSSASSKQNSKM 138
Score = 40.4 bits (93), Expect = 0.004
Identities = 21/66 (31%), Positives = 32/66 (48%), Gaps = 7/66 (10%)
Query: 474 CKTCGKTFSCSYTLRRHATVHTRERPYECRYCLRSYTQSGDLYRHIRKAHNEDLAKRSKP 533
C CGK F LR H TVHT+E+ + C+ C + + + L + HN+ +
Sbjct: 580 CNLCGKGFYQRCHLREHYTVHTKEKQFVCQTCGKQFLRERQL-----RLHND--MHKGMA 632
Query: 534 DPEVGP 539
E+GP
Sbjct: 633 SGEIGP 638
>gi|23397572 kelch-like 34 [Homo sapiens]
Length = 644
Score = 79.0 bits (193), Expect = 1e-14
Identities = 46/121 (38%), Positives = 68/121 (56%), Gaps = 2/121 (1%)
Query: 56 HSQQLLQSLREQRSQGFLCDCTVMVGSTQFLAHRAVLASCSPFFQLFYKERELDKRDLVC 115
H LL + R++GFLCD T+ ++F AHR++LA S +F+ +K + R V
Sbjct: 11 HGGALLTGYQALRAEGFLCDVTLETEGSEFPAHRSLLACSSDYFRALFKSHTQESRARV- 69
Query: 116 IHNEIVTAPAFGLLLDFMYAGQLTLRGDTPVEDVLAAASYLHMNDIVKVCKRRLQARALA 175
IH + +A LLDF+Y L+L DT VED L AASYL + + + +C R L+ +
Sbjct: 70 IHLHVPSAAGLQRLLDFIYTAWLSLSMDT-VEDTLEAASYLQVTEALGLCGRYLERQLAP 128
Query: 176 E 176
E
Sbjct: 129 E 129
>gi|157694497 zinc finger and BTB domain containing 10 isoform b
[Homo sapiens]
Length = 847
Score = 76.6 bits (187), Expect = 6e-14
Identities = 40/110 (36%), Positives = 64/110 (58%), Gaps = 4/110 (3%)
Query: 59 QLLQSLREQRSQGFLCDCTVMVGSTQFLAHRAVLASCSPFFQLFY--KERELDKRDLVCI 116
QLL+ L EQR +G LCD +++V F AH+ +L + S FF+ Y +E ++
Sbjct: 349 QLLRQLNEQRKKGILCDVSIVVSGKIFKAHKNILVAGSRFFKTLYCFSNKESPNQNNT-T 407
Query: 117 HNEIVTAPAFGLLLDFMYAGQLTLRGDTPVEDVLAAASYLHMNDIVKVCK 166
H +I F ++LDF+Y+G L L +E V+ ASYL M+++V+ C+
Sbjct: 408 HLDIAAVQGFSVILDFLYSGNLVLTSQNAIE-VMTVASYLQMSEVVQTCR 456
Score = 39.3 bits (90), Expect = 0.010
Identities = 19/69 (27%), Positives = 37/69 (53%), Gaps = 3/69 (4%)
Query: 473 TCKTCGKTFSCSYTLRRHATVHTRERPYECRYCLRSYTQSGDL-YRHIRKAHN--EDLAK 529
+C CGK F+ ++RH+ VH +++ Y+C C + + + + RH + + D A
Sbjct: 727 SCDICGKLFTRREHVKRHSLVHKKDKKYKCMVCKKIFMLAASVGIRHGSRRYGVCVDCAD 786
Query: 530 RSKPDPEVG 538
+S+P + G
Sbjct: 787 KSQPGGQEG 795
Score = 37.0 bits (84), Expect = 0.049
Identities = 39/167 (23%), Positives = 59/167 (35%), Gaps = 24/167 (14%)
Query: 363 DEETDVSDEQPQGPERAFPSGGAVY--------GAQPSQPEAFEDPGAAGLEEVGPSDHF 414
+ ET++ D P A+P + GA S P+ + A L E G S
Sbjct: 591 NNETNLEDCSVMQPPVAYPEENTLLIKEEPDLDGALLSGPDGDRNVNANLLAEAGTSQDG 650
Query: 415 --LPTDPHLPYHLLPGAGQ-YHRGLVTSPLPAPASLHEPLYLSSEYEAAPGSFGVFTEDV 471
T Y L+PGA + GL+ P + G + +
Sbjct: 651 GDAGTSHDFKYGLMPGASNDFKYGLLPESWPKQETWEN------------GESSLIMNKL 698
Query: 472 PTCKTCGKTFSCSYTLRRHATVHTRERPYECRYCLRSYTQSGDLYRH 518
C C TL+RH +HT R + C C + +T+ + RH
Sbjct: 699 K-CPHCSYVAKYRRTLKRHLLIHTGVRSFSCDICGKLFTRREHVKRH 744
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.132 0.402
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 28,416,395
Number of Sequences: 37866
Number of extensions: 1721430
Number of successful extensions: 23052
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1174
Number of HSP's successfully gapped in prelim test: 778
Number of HSP's that attempted gapping in prelim test: 8254
Number of HSP's gapped (non-prelim): 13497
length of query: 574
length of database: 18,247,518
effective HSP length: 108
effective length of query: 466
effective length of database: 14,157,990
effective search space: 6597623340
effective search space used: 6597623340
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.