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Search of human proteins with 13325055
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|13325055 solute carrier family 27 (fatty acid transporter),
member 6 [Homo sapiens]
(619 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|62865631 solute carrier family 27 (fatty acid transporter), m... 1255 0.0
gi|13325055 solute carrier family 27 (fatty acid transporter), m... 1255 0.0
gi|227499619 solute carrier family 27 (fatty acid transporter), ... 648 0.0
gi|227499621 solute carrier family 27 (fatty acid transporter), ... 571 e-163
gi|13236579 solute carrier family 27 member 3 [Homo sapiens] 518 e-147
gi|13325057 solute carrier family 27 (fatty acid transporter), m... 497 e-140
gi|40807357 solute carrier family 27 (fatty acid transporter), m... 422 e-118
gi|38524616 solute carrier family 27, member 1 [Homo sapiens] 410 e-114
gi|28416953 acyl-CoA synthetase short-chain family member 1 [Hom... 69 1e-11
gi|42544132 SA hypertension-associated homolog isoform 1 [Homo s... 67 5e-11
gi|122937307 acyl-CoA synthetase medium-chain family member 4 [H... 64 3e-10
gi|157311624 acyl-CoA synthetase medium-chain family member 2B [... 64 4e-10
gi|157311622 acyl-CoA synthetase medium-chain family member 2B [... 64 4e-10
gi|38505220 acyl-CoA synthetase medium-chain family member 5 [Ho... 62 2e-09
gi|115511026 acyl-CoA synthetase medium-chain family member 1 [H... 62 2e-09
gi|239756507 PREDICTED: similar to Acyl-coenzyme A synthetase AC... 61 3e-09
gi|239756505 PREDICTED: similar to Acyl-coenzyme A synthetase AC... 61 3e-09
gi|58082049 acyl-CoA synthetase medium-chain family member 2A [H... 60 6e-09
gi|187761345 acyl-CoA synthetase family member 3 [Homo sapiens] 60 8e-09
gi|187761343 acyl-CoA synthetase family member 3 [Homo sapiens] 60 8e-09
gi|13375727 acyl-CoA synthetase short-chain family member 3 [Hom... 58 3e-08
gi|42544134 SA hypertension-associated homolog isoform 2 [Homo s... 54 6e-07
gi|8923896 acyl-CoA synthetase short-chain family member 2 isofo... 50 6e-06
gi|253970489 acyl-CoA synthetase short-chain family member 2 iso... 45 2e-04
gi|156151445 acyl-CoA synthetase family member 2 [Homo sapiens] 42 0.001
gi|195947378 acyl-coenzyme A synthetase ACSM6, mitochondrial [Ho... 42 0.002
gi|27477105 lipidosin [Homo sapiens] 40 0.006
gi|42794760 acyl-CoA synthetase long-chain family member 5 isofo... 37 0.041
gi|42794758 acyl-CoA synthetase long-chain family member 5 isofo... 37 0.041
gi|42794756 acyl-CoA synthetase long-chain family member 5 isofo... 37 0.041
>gi|62865631 solute carrier family 27 (fatty acid transporter),
member 6 [Homo sapiens]
Length = 619
Score = 1255 bits (3247), Expect = 0.0
Identities = 619/619 (100%), Positives = 619/619 (100%)
Query: 1 MLLSWLTVLGAGMVVLHFLQKLLFPYFWDDFWFVLKVVLIIIRLKKYEKRGELVTVLDKF 60
MLLSWLTVLGAGMVVLHFLQKLLFPYFWDDFWFVLKVVLIIIRLKKYEKRGELVTVLDKF
Sbjct: 1 MLLSWLTVLGAGMVVLHFLQKLLFPYFWDDFWFVLKVVLIIIRLKKYEKRGELVTVLDKF 60
Query: 61 LSHAKRQPRKPFIIYEGDIYTYQDVDKRSSRVAHVFLNHSSLKKGDTVALLMSNEPDFVH 120
LSHAKRQPRKPFIIYEGDIYTYQDVDKRSSRVAHVFLNHSSLKKGDTVALLMSNEPDFVH
Sbjct: 61 LSHAKRQPRKPFIIYEGDIYTYQDVDKRSSRVAHVFLNHSSLKKGDTVALLMSNEPDFVH 120
Query: 121 VWFGLAKLGCVVAFLNTNIRSNSLLNCIRACGPRALVVGADLLGTVEEILPSLSENISVW 180
VWFGLAKLGCVVAFLNTNIRSNSLLNCIRACGPRALVVGADLLGTVEEILPSLSENISVW
Sbjct: 121 VWFGLAKLGCVVAFLNTNIRSNSLLNCIRACGPRALVVGADLLGTVEEILPSLSENISVW 180
Query: 181 GMKDSVPQGVISLKEKLSTSPDEPVPRSHHVVSLLKSTCLYIFTSGTTGLPKAAVISQLQ 240
GMKDSVPQGVISLKEKLSTSPDEPVPRSHHVVSLLKSTCLYIFTSGTTGLPKAAVISQLQ
Sbjct: 181 GMKDSVPQGVISLKEKLSTSPDEPVPRSHHVVSLLKSTCLYIFTSGTTGLPKAAVISQLQ 240
Query: 241 VLRGSAVLWAFGCTAHDIVYITLPLYHSSAAILGISGCVELGATCVLKKKFSASQFWSDC 300
VLRGSAVLWAFGCTAHDIVYITLPLYHSSAAILGISGCVELGATCVLKKKFSASQFWSDC
Sbjct: 241 VLRGSAVLWAFGCTAHDIVYITLPLYHSSAAILGISGCVELGATCVLKKKFSASQFWSDC 300
Query: 301 KKYDVTVFQYIGELCRYLCKQSKREGEKDHKVRLAIGNGIRSDVWREFLDRFGNIKVCEL 360
KKYDVTVFQYIGELCRYLCKQSKREGEKDHKVRLAIGNGIRSDVWREFLDRFGNIKVCEL
Sbjct: 301 KKYDVTVFQYIGELCRYLCKQSKREGEKDHKVRLAIGNGIRSDVWREFLDRFGNIKVCEL 360
Query: 361 YAATESSISFMNYTGRIGAIGRTNLFYKLLSTFDLIKYDFQKDEPMRNEQGWCIHVKKGE 420
YAATESSISFMNYTGRIGAIGRTNLFYKLLSTFDLIKYDFQKDEPMRNEQGWCIHVKKGE
Sbjct: 361 YAATESSISFMNYTGRIGAIGRTNLFYKLLSTFDLIKYDFQKDEPMRNEQGWCIHVKKGE 420
Query: 421 PGLLISRVNAKNPFFGYAGPYKHTKDKLLCDVFKKGDVYLNTGDLIVQDQDNFLYFWDRT 480
PGLLISRVNAKNPFFGYAGPYKHTKDKLLCDVFKKGDVYLNTGDLIVQDQDNFLYFWDRT
Sbjct: 421 PGLLISRVNAKNPFFGYAGPYKHTKDKLLCDVFKKGDVYLNTGDLIVQDQDNFLYFWDRT 480
Query: 481 GDTFRWKGENVATTEVADVIGMLDFIQEANVYGVAISGYEGRAGMASIILKPNTSLDLEK 540
GDTFRWKGENVATTEVADVIGMLDFIQEANVYGVAISGYEGRAGMASIILKPNTSLDLEK
Sbjct: 481 GDTFRWKGENVATTEVADVIGMLDFIQEANVYGVAISGYEGRAGMASIILKPNTSLDLEK 540
Query: 541 VYEQVVTFLPAYACPRFLRIQEKMEATGTFKLLKHQLVEDGFNPLKISEPLYFMDNLKKS 600
VYEQVVTFLPAYACPRFLRIQEKMEATGTFKLLKHQLVEDGFNPLKISEPLYFMDNLKKS
Sbjct: 541 VYEQVVTFLPAYACPRFLRIQEKMEATGTFKLLKHQLVEDGFNPLKISEPLYFMDNLKKS 600
Query: 601 YVLLTRELYDQIMLGEIKL 619
YVLLTRELYDQIMLGEIKL
Sbjct: 601 YVLLTRELYDQIMLGEIKL 619
>gi|13325055 solute carrier family 27 (fatty acid transporter),
member 6 [Homo sapiens]
Length = 619
Score = 1255 bits (3247), Expect = 0.0
Identities = 619/619 (100%), Positives = 619/619 (100%)
Query: 1 MLLSWLTVLGAGMVVLHFLQKLLFPYFWDDFWFVLKVVLIIIRLKKYEKRGELVTVLDKF 60
MLLSWLTVLGAGMVVLHFLQKLLFPYFWDDFWFVLKVVLIIIRLKKYEKRGELVTVLDKF
Sbjct: 1 MLLSWLTVLGAGMVVLHFLQKLLFPYFWDDFWFVLKVVLIIIRLKKYEKRGELVTVLDKF 60
Query: 61 LSHAKRQPRKPFIIYEGDIYTYQDVDKRSSRVAHVFLNHSSLKKGDTVALLMSNEPDFVH 120
LSHAKRQPRKPFIIYEGDIYTYQDVDKRSSRVAHVFLNHSSLKKGDTVALLMSNEPDFVH
Sbjct: 61 LSHAKRQPRKPFIIYEGDIYTYQDVDKRSSRVAHVFLNHSSLKKGDTVALLMSNEPDFVH 120
Query: 121 VWFGLAKLGCVVAFLNTNIRSNSLLNCIRACGPRALVVGADLLGTVEEILPSLSENISVW 180
VWFGLAKLGCVVAFLNTNIRSNSLLNCIRACGPRALVVGADLLGTVEEILPSLSENISVW
Sbjct: 121 VWFGLAKLGCVVAFLNTNIRSNSLLNCIRACGPRALVVGADLLGTVEEILPSLSENISVW 180
Query: 181 GMKDSVPQGVISLKEKLSTSPDEPVPRSHHVVSLLKSTCLYIFTSGTTGLPKAAVISQLQ 240
GMKDSVPQGVISLKEKLSTSPDEPVPRSHHVVSLLKSTCLYIFTSGTTGLPKAAVISQLQ
Sbjct: 181 GMKDSVPQGVISLKEKLSTSPDEPVPRSHHVVSLLKSTCLYIFTSGTTGLPKAAVISQLQ 240
Query: 241 VLRGSAVLWAFGCTAHDIVYITLPLYHSSAAILGISGCVELGATCVLKKKFSASQFWSDC 300
VLRGSAVLWAFGCTAHDIVYITLPLYHSSAAILGISGCVELGATCVLKKKFSASQFWSDC
Sbjct: 241 VLRGSAVLWAFGCTAHDIVYITLPLYHSSAAILGISGCVELGATCVLKKKFSASQFWSDC 300
Query: 301 KKYDVTVFQYIGELCRYLCKQSKREGEKDHKVRLAIGNGIRSDVWREFLDRFGNIKVCEL 360
KKYDVTVFQYIGELCRYLCKQSKREGEKDHKVRLAIGNGIRSDVWREFLDRFGNIKVCEL
Sbjct: 301 KKYDVTVFQYIGELCRYLCKQSKREGEKDHKVRLAIGNGIRSDVWREFLDRFGNIKVCEL 360
Query: 361 YAATESSISFMNYTGRIGAIGRTNLFYKLLSTFDLIKYDFQKDEPMRNEQGWCIHVKKGE 420
YAATESSISFMNYTGRIGAIGRTNLFYKLLSTFDLIKYDFQKDEPMRNEQGWCIHVKKGE
Sbjct: 361 YAATESSISFMNYTGRIGAIGRTNLFYKLLSTFDLIKYDFQKDEPMRNEQGWCIHVKKGE 420
Query: 421 PGLLISRVNAKNPFFGYAGPYKHTKDKLLCDVFKKGDVYLNTGDLIVQDQDNFLYFWDRT 480
PGLLISRVNAKNPFFGYAGPYKHTKDKLLCDVFKKGDVYLNTGDLIVQDQDNFLYFWDRT
Sbjct: 421 PGLLISRVNAKNPFFGYAGPYKHTKDKLLCDVFKKGDVYLNTGDLIVQDQDNFLYFWDRT 480
Query: 481 GDTFRWKGENVATTEVADVIGMLDFIQEANVYGVAISGYEGRAGMASIILKPNTSLDLEK 540
GDTFRWKGENVATTEVADVIGMLDFIQEANVYGVAISGYEGRAGMASIILKPNTSLDLEK
Sbjct: 481 GDTFRWKGENVATTEVADVIGMLDFIQEANVYGVAISGYEGRAGMASIILKPNTSLDLEK 540
Query: 541 VYEQVVTFLPAYACPRFLRIQEKMEATGTFKLLKHQLVEDGFNPLKISEPLYFMDNLKKS 600
VYEQVVTFLPAYACPRFLRIQEKMEATGTFKLLKHQLVEDGFNPLKISEPLYFMDNLKKS
Sbjct: 541 VYEQVVTFLPAYACPRFLRIQEKMEATGTFKLLKHQLVEDGFNPLKISEPLYFMDNLKKS 600
Query: 601 YVLLTRELYDQIMLGEIKL 619
YVLLTRELYDQIMLGEIKL
Sbjct: 601 YVLLTRELYDQIMLGEIKL 619
>gi|227499619 solute carrier family 27 (fatty acid transporter),
member 2 isoform 1 [Homo sapiens]
Length = 620
Score = 648 bits (1672), Expect = 0.0
Identities = 316/621 (50%), Positives = 431/621 (69%), Gaps = 3/621 (0%)
Query: 1 MLLSWLTVLGAGMVVLHFLQKLLFPYFWDDFWFVLKVVLIIIRLKKYEKRGELVTVLDKF 60
ML + TVL AG++ L L L PYF+ D + LKV + R++ Y KR T+L F
Sbjct: 1 MLSAIYTVL-AGLLFLPLLVNLCCPYFFQDIGYFLKVAAVGRRVRSYGKRRPARTILRAF 59
Query: 61 LSHAKRQPRKPFIIYEGDIYTYQDVDKRSSRVAHVFLNHSSLKKGDTVALLMSNEPDFVH 120
L A++ P KPF+++ + TY VD+RS++VA +H L++GD VALLM NEP +V
Sbjct: 60 LEKARQTPHKPFLLFRDETLTYAQVDRRSNQVARALHDHLGLRQGDCVALLMGNEPAYVW 119
Query: 121 VWFGLAKLGCVVAFLNTNIRSNSLLNCIRACGPRALVVGADLLGTVEEILPSLS-ENISV 179
+W GL KLGC +A LN NIR+ SLL+C + CG + L+V +L VEEILPSL +++S+
Sbjct: 120 LWLGLVKLGCAMACLNYNIRAKSLLHCFQCCGAKVLLVSPELQAAVEEILPSLKKDDVSI 179
Query: 180 WGM-KDSVPQGVISLKEKLSTSPDEPVPRSHHVVSLLKSTCLYIFTSGTTGLPKAAVISQ 238
+ + + S G+ S +K+ EP+P S + LYI+TSGTTGLPKAA+I+
Sbjct: 180 YYVSRTSNTDGIDSFLDKVDEVSTEPIPESWRSEVTFSTPALYIYTSGTTGLPKAAMITH 239
Query: 239 LQVLRGSAVLWAFGCTAHDIVYITLPLYHSSAAILGISGCVELGATCVLKKKFSASQFWS 298
++ G+ + + G A D++YITLP YHS+A ++GI GC+ GAT L+ KFSASQFW
Sbjct: 240 QRIWYGTGLTFVSGLKADDVIYITLPFYHSAALLIGIHGCIVAGATLALRTKFSASQFWD 299
Query: 299 DCKKYDVTVFQYIGELCRYLCKQSKREGEKDHKVRLAIGNGIRSDVWREFLDRFGNIKVC 358
DC+KY+VTV QYIGEL RYLC ++ ++DHKVRLA+GNG+R DVWR+F+ RFG+I +
Sbjct: 300 DCRKYNVTVIQYIGELLRYLCNSPQKPNDRDHKVRLALGNGLRGDVWRQFVKRFGDICIY 359
Query: 359 ELYAATESSISFMNYTGRIGAIGRTNLFYKLLSTFDLIKYDFQKDEPMRNEQGWCIHVKK 418
E YAATE +I FMNY ++GA+GR N K + T+DLIKYD +KDEP+R+E G+C+ V K
Sbjct: 360 EFYAATEGNIGFMNYARKVGAVGRVNYLQKKIITYDLIKYDVEKDEPVRDENGYCVRVPK 419
Query: 419 GEPGLLISRVNAKNPFFGYAGPYKHTKDKLLCDVFKKGDVYLNTGDLIVQDQDNFLYFWD 478
GE GLL+ ++ PF GYAG T+ K L DVFKKGD+Y N+GDL++ D +NF+YF D
Sbjct: 420 GEVGLLVCKITQLTPFNGYAGAKAQTEKKKLRDVFKKGDLYFNSGDLLMVDHENFIYFHD 479
Query: 479 RTGDTFRWKGENVATTEVADVIGMLDFIQEANVYGVAISGYEGRAGMASIILKPNTSLDL 538
R GDTFRWKGENVATTEVAD +G++DF+QE NVYGV + +EGR GMASI +K N D
Sbjct: 480 RVGDTFRWKGENVATTEVADTVGLVDFVQEVNVYGVHVPDHEGRIGMASIKMKENHEFDG 539
Query: 539 EKVYEQVVTFLPAYACPRFLRIQEKMEATGTFKLLKHQLVEDGFNPLKISEPLYFMDNLK 598
+K+++ + +LP+YA PRFLRIQ+ +E TGTFK K LVE+GFNP I + LYF+D+
Sbjct: 540 KKLFQHIADYLPSYARPRFLRIQDTIEITGTFKHRKMTLVEEGFNPAVIKDALYFLDDTA 599
Query: 599 KSYVLLTRELYDQIMLGEIKL 619
K YV +T ++Y+ I +KL
Sbjct: 600 KMYVPMTEDIYNAISAKTLKL 620
>gi|227499621 solute carrier family 27 (fatty acid transporter),
member 2 isoform 2 [Homo sapiens]
Length = 567
Score = 571 bits (1471), Expect = e-163
Identities = 292/621 (47%), Positives = 394/621 (63%), Gaps = 56/621 (9%)
Query: 1 MLLSWLTVLGAGMVVLHFLQKLLFPYFWDDFWFVLKVVLIIIRLKKYEKRGELVTVLDKF 60
ML + TVL AG++ L L L PYF+ D + LKV + R++ Y KR T+L F
Sbjct: 1 MLSAIYTVL-AGLLFLPLLVNLCCPYFFQDIGYFLKVAAVGRRVRSYGKRRPARTILRAF 59
Query: 61 LSHAKRQPRKPFIIYEGDIYTYQDVDKRSSRVAHVFLNHSSLKKGDTVALLMSNEPDFVH 120
L A++ P KPF+++ + TY VD+RS++VA +H L++GD VALLM NEP +V
Sbjct: 60 LEKARQTPHKPFLLFRDETLTYAQVDRRSNQVARALHDHLGLRQGDCVALLMGNEPAYVW 119
Query: 121 VWFGLAKLGCVVAFLNTNIRSNSLLNCIRACGPRALVVGADLLGTVEEILPSLS-ENISV 179
+W GL KLGC +A LN NIR+ SLL+C + CG + L+V +L VEEILPSL +++S+
Sbjct: 120 LWLGLVKLGCAMACLNYNIRAKSLLHCFQCCGAKVLLVSPELQAAVEEILPSLKKDDVSI 179
Query: 180 WGM-KDSVPQGVISLKEKLSTSPDEPVPRSHHVVSLLKSTCLYIFTSGTTGLPKAAVISQ 238
+ + + S G+ S +K+ EP+P S + LYI+TSGTT
Sbjct: 180 YYVSRTSNTDGIDSFLDKVDEVSTEPIPESWRSEVTFSTPALYIYTSGTT---------- 229
Query: 239 LQVLRGSAVLWAFGCTAHDIVYITLPLYHSSAAILGISGCVELGATCVLKKKFSASQFWS 298
GAT L+ KFSASQFW
Sbjct: 230 -------------------------------------------GATLALRTKFSASQFWD 246
Query: 299 DCKKYDVTVFQYIGELCRYLCKQSKREGEKDHKVRLAIGNGIRSDVWREFLDRFGNIKVC 358
DC+KY+VTV QYIGEL RYLC ++ ++DHKVRLA+GNG+R DVWR+F+ RFG+I +
Sbjct: 247 DCRKYNVTVIQYIGELLRYLCNSPQKPNDRDHKVRLALGNGLRGDVWRQFVKRFGDICIY 306
Query: 359 ELYAATESSISFMNYTGRIGAIGRTNLFYKLLSTFDLIKYDFQKDEPMRNEQGWCIHVKK 418
E YAATE +I FMNY ++GA+GR N K + T+DLIKYD +KDEP+R+E G+C+ V K
Sbjct: 307 EFYAATEGNIGFMNYARKVGAVGRVNYLQKKIITYDLIKYDVEKDEPVRDENGYCVRVPK 366
Query: 419 GEPGLLISRVNAKNPFFGYAGPYKHTKDKLLCDVFKKGDVYLNTGDLIVQDQDNFLYFWD 478
GE GLL+ ++ PF GYAG T+ K L DVFKKGD+Y N+GDL++ D +NF+YF D
Sbjct: 367 GEVGLLVCKITQLTPFNGYAGAKAQTEKKKLRDVFKKGDLYFNSGDLLMVDHENFIYFHD 426
Query: 479 RTGDTFRWKGENVATTEVADVIGMLDFIQEANVYGVAISGYEGRAGMASIILKPNTSLDL 538
R GDTFRWKGENVATTEVAD +G++DF+QE NVYGV + +EGR GMASI +K N D
Sbjct: 427 RVGDTFRWKGENVATTEVADTVGLVDFVQEVNVYGVHVPDHEGRIGMASIKMKENHEFDG 486
Query: 539 EKVYEQVVTFLPAYACPRFLRIQEKMEATGTFKLLKHQLVEDGFNPLKISEPLYFMDNLK 598
+K+++ + +LP+YA PRFLRIQ+ +E TGTFK K LVE+GFNP I + LYF+D+
Sbjct: 487 KKLFQHIADYLPSYARPRFLRIQDTIEITGTFKHRKMTLVEEGFNPAVIKDALYFLDDTA 546
Query: 599 KSYVLLTRELYDQIMLGEIKL 619
K YV +T ++Y+ I +KL
Sbjct: 547 KMYVPMTEDIYNAISAKTLKL 567
>gi|13236579 solute carrier family 27 member 3 [Homo sapiens]
Length = 730
Score = 518 bits (1334), Expect = e-147
Identities = 258/520 (49%), Positives = 349/520 (67%), Gaps = 2/520 (0%)
Query: 102 LKKGDTVALLMSNEPDFVHVWFGLAKLGCVVAFLNTNIRSNSLLNCIRACGPRALVVGAD 161
L G TVALL+ P+F+ +WFGLAK G AF+ T +R LL+C+R+CG RALV+ +
Sbjct: 211 LSPGATVALLLPAGPEFLWLWFGLAKAGLRTAFVPTALRRGPLLHCLRSCGARALVLAPE 270
Query: 162 LLGTVEEILPSL-SENISVWGMKDSV-PQGVISLKEKLSTSPDEPVPRSHHVVSLLKSTC 219
L ++E LP+L + + +W P G+ L ++S D PVP + TC
Sbjct: 271 FLESLEPDLPALRAMGLHLWAAGPGTHPAGISDLLAEVSAEVDGPVPGYLSSPQSITDTC 330
Query: 220 LYIFTSGTTGLPKAAVISQLQVLRGSAVLWAFGCTAHDIVYITLPLYHSSAAILGISGCV 279
LYIFTSGTTGLPKAA IS L++L+ G D++Y+ LPLYH S ++LGI GC+
Sbjct: 331 LYIFTSGTTGLPKAARISHLKILQCQGFYQLCGVHQEDVIYLALPLYHMSGSLLGIVGCM 390
Query: 280 ELGATCVLKKKFSASQFWSDCKKYDVTVFQYIGELCRYLCKQSKREGEKDHKVRLAIGNG 339
+GAT VLK KFSA QFW DC+++ VTVFQYIGELCRYL Q + E+ HKVRLA+G+G
Sbjct: 391 GIGATVVLKSKFSAGQFWEDCQQHRVTVFQYIGELCRYLVNQPPSKAERGHKVRLAVGSG 450
Query: 340 IRSDVWREFLDRFGNIKVCELYAATESSISFMNYTGRIGAIGRTNLFYKLLSTFDLIKYD 399
+R D W F+ RFG ++V E Y TE +++ +NYTG+ GA+GR + YK + F LI+YD
Sbjct: 451 LRPDTWERFVRRFGPLQVLETYGLTEGNVATINYTGQRGAVGRASWLYKHIFPFSLIRYD 510
Query: 400 FQKDEPMRNEQGWCIHVKKGEPGLLISRVNAKNPFFGYAGPYKHTKDKLLCDVFKKGDVY 459
EP+R+ QG C+ GEPGLL++ V+ ++PF GYAG + + KLL DVF+ GDV+
Sbjct: 511 VTTGEPIRDPQGHCMATSPGEPGLLVAPVSQQSPFLGYAGGPELAQGKLLKDVFRPGDVF 570
Query: 460 LNTGDLIVQDQDNFLYFWDRTGDTFRWKGENVATTEVADVIGMLDFIQEANVYGVAISGY 519
NTGDL+V D FL F DRTGDTFRWKGENVATTEVA+V LDF+QE NVYGV + G+
Sbjct: 571 FNTGDLLVCDDQGFLRFHDRTGDTFRWKGENVATTEVAEVFEALDFLQEVNVYGVTVPGH 630
Query: 520 EGRAGMASIILKPNTSLDLEKVYEQVVTFLPAYACPRFLRIQEKMEATGTFKLLKHQLVE 579
EGRAGMA+++L+P +LDL ++Y V LP YA PRFLR+QE + T TFK K ++
Sbjct: 631 EGRAGMAALVLRPPHALDLMQLYTHVSENLPPYARPRFLRLQESLATTETFKQQKVRMAN 690
Query: 580 DGFNPLKISEPLYFMDNLKKSYVLLTRELYDQIMLGEIKL 619
+GF+P +S+PLY +D +Y+ LT Y ++ G +++
Sbjct: 691 EGFDPSTLSDPLYVLDQAVGAYLPLTTARYSALLAGNLRI 730
>gi|13325057 solute carrier family 27 (fatty acid transporter),
member 5 [Homo sapiens]
Length = 690
Score = 497 bits (1280), Expect = e-140
Identities = 259/601 (43%), Positives = 385/601 (64%), Gaps = 11/601 (1%)
Query: 30 DFWFVLKVVLIIIRLKKYEKRGELVTVLDKFLSHAKRQPRKPFIIYEGD---IYTYQDVD 86
D F+ K++ + ++++ R T +D F A+ QP + +++ G T+ ++D
Sbjct: 90 DVIFLAKILHLGLKIRGCLSRQPPDTFVDAFERRARAQPGRALLVWTGPGAGSVTFGELD 149
Query: 87 KRSSRVAHVFL----NHSSLKKGDTVALLM--SNEPDFVHVWFGLAKLGCVVAFLNTNIR 140
R+ + A + +SL G+ ALL+ S + +W GLAKLGC A++N + R
Sbjct: 150 ARACQAAWALKAELGDPASLCAGEPTALLVLASQAVPALCMWLGLAKLGCPTAWINPHGR 209
Query: 141 SNSLLNCIRACGPRALVVGADLLGTVEEILPSL-SENISVWGMKDSVPQ-GVISLKEKLS 198
L + + + G R LVV DL ++EEILP L +ENI + + + P GV +L L
Sbjct: 210 GMPLAHSVLSSGARVLVVDPDLRESLEEILPKLQAENIRCFYLSHTSPTPGVGALGAALD 269
Query: 199 TSPDEPVPRSHHVVSLLKSTCLYIFTSGTTGLPKAAVISQLQVLRGSAVLWAFGCTAHDI 258
+P PVP +S L+I+TSGTTGLPK A+++ +VL+ S +L G TA D+
Sbjct: 270 AAPSHPVPADLRAGITWRSPALFIYTSGTTGLPKPAILTHERVLQMSKMLSLSGATADDV 329
Query: 259 VYITLPLYHSSAAILGISGCVELGATCVLKKKFSASQFWSDCKKYDVTVFQYIGELCRYL 318
VY LPLYH ++GI GC++LGATCVL KFS S FW DC+++ VTV Y+GEL RYL
Sbjct: 330 VYTVLPLYHVMGLVVGILGCLDLGATCVLAPKFSTSCFWDDCRQHGVTVILYVGELLRYL 389
Query: 319 CKQSKREGEKDHKVRLAIGNGIRSDVWREFLDRFGNIKVCELYAATESSISFMNYTGRIG 378
C ++ ++ H VRLA+GNG+R+DVW F RFG I++ E+Y +TE ++ +NY GR G
Sbjct: 390 CNIPQQPEDRTHTVRLAMGNGLRADVWETFQQRFGPIRIWEVYGSTEGNMGLVNYVGRCG 449
Query: 379 AIGRTNLFYKLLSTFDLIKYDFQKDEPMRNEQGWCIHVKKGEPGLLISRVNAKNPFFGYA 438
A+G+ + ++LS F+L+++D + EP+R+ QG+CI V GEPGLL+++V ++ PF GY
Sbjct: 450 ALGKMSCLLRMLSPFELVQFDMEAAEPVRDNQGFCIPVGLGEPGLLLTKVVSQQPFVGYR 509
Query: 439 GPYKHTKDKLLCDVFKKGDVYLNTGDLIVQDQDNFLYFWDRTGDTFRWKGENVATTEVAD 498
GP + ++ KL+ +V + GDVY NTGD++ D++ FLYF DR GDTFRWKGENV+T EV
Sbjct: 510 GPRELSERKLVRNVRQSGDVYYNTGDVLAMDREGFLYFRDRLGDTFRWKGENVSTHEVEG 569
Query: 499 VIGMLDFIQEANVYGVAISGYEGRAGMASIILKPNTSLDLEKVYEQVVTFLPAYACPRFL 558
V+ +DF+Q+ NVYGV + G EG+ GMA++ L P + D EK+Y+ V +LPAYA P F+
Sbjct: 570 VLSQVDFLQQVNVYGVCVPGCEGKVGMAAVQLAPGQTFDGEKLYQHVRAWLPAYATPHFI 629
Query: 559 RIQEKMEATGTFKLLKHQLVEDGFNPLKISEPLYFMDNLKKSYVLLTRELYDQIMLGEIK 618
RIQ+ ME T TFKL+K +LV +GFN + +PL+ +DN +S+ LT E+Y + G +
Sbjct: 630 RIQDAMEVTSTFKLMKTRLVREGFNVGIVVDPLFVLDNRAQSFRPLTAEMYQAVCEGTWR 689
Query: 619 L 619
L
Sbjct: 690 L 690
>gi|40807357 solute carrier family 27 (fatty acid transporter),
member 4 [Homo sapiens]
Length = 643
Score = 422 bits (1084), Expect = e-118
Identities = 249/618 (40%), Positives = 350/618 (56%), Gaps = 23/618 (3%)
Query: 22 LLFPYFWDDFWFVLKV-------------VLIIIRLKKYEKRGELVTVLDKFLSHAKRQP 68
LLF Y W ++V VL+ ++ K + E TV F S +R P
Sbjct: 29 LLFLYLGSGGWRFIRVFIKTIRRDIFGGLVLLKVKAKVRQCLQERRTVPILFASTVRRHP 88
Query: 69 RKPFIIYEGDI--YTYQDVDKRSSRVAHVFLNHSSLKKGDTVALLMSNEPDFVHVWFGLA 126
K +I+EG +T++ +D+ SS VA+ FL L GD A+ M N +FV +W G+A
Sbjct: 89 DKTALIFEGTDTHWTFRQLDEYSSSVAN-FLQARGLASGDVAAIFMENRNEFVGLWLGMA 147
Query: 127 KLGCVVAFLNTNIRSNSLLNCIRACGPRALVVGADLLGTVEEILPSLSENISVWGMKDSV 186
KLG A +NTN+R ++LL+C+ RALV G+++ + E+ SL ++S++
Sbjct: 148 KLGVEAALINTNLRRDALLHCLTTSRARALVFGSEMASAICEVHASLDPSLSLFCSGSWE 207
Query: 187 PQGVISLKEKLSTS-PDEPVPRSHHVVSLLKSTCLYIFTSGTTGLPKAAVISQLQVLRGS 245
P V E L D P YI+TSGTTGLPKAA++ + R +
Sbjct: 208 PGAVPPSTEHLDPLLKDAPKHLPSCPDKGFTDKLFYIYTSGTTGLPKAAIVVHSRYYRMA 267
Query: 246 A-VLWAFGCTAHDIVYITLPLYHSSAAILGISGCVELGATCVLKKKFSASQFWSDCKKYD 304
A V + F +DIVY LPLYHS+ I+GI C+ G T V++KKFSAS+FW DC KY+
Sbjct: 268 ALVYYGFRMRPNDIVYDCLPLYHSAGNIVGIGQCLLHGMTVVIRKKFSASRFWDDCIKYN 327
Query: 305 VTVFQYIGELCRYLCKQSKREGEKDHKVRLAIGNGIRSDVWREFLDRFGNIKVCELYAAT 364
T+ QYIGELCRYL Q RE E H+VR+A+GNG+R +W F RF +V E Y AT
Sbjct: 328 CTIVQYIGELCRYLLNQPPREAENQHQVRMALGNGLRQSIWTNFSSRFHIPQVAEFYGAT 387
Query: 365 ESSISFMNYTGRIGAIGRTNLFYKLLSTFDLIKYDFQKDEPMRNEQGWCIHVKKGEPGLL 424
E + S N+ ++GA G + + L++ + E +R G CI + GEPG L
Sbjct: 388 ECNCSLGNFDSQVGACGFNSRILSFVYPIRLVRVNEDTMELIRGPDGVCIPCQPGEPGQL 447
Query: 425 ISRVNAKNP---FFGYAGPYKHTKDKLLCDVFKKGDVYLNTGDLIVQDQDNFLYFWDRTG 481
+ R+ K+P F GY + K K+ DVFKKGD TGD++V D+ +LYF DRTG
Sbjct: 448 VGRIIQKDPLRRFDGYLNQGANNK-KIAKDVFKKGDQAYLTGDVLVMDELGYLYFRDRTG 506
Query: 482 DTFRWKGENVATTEVADVIGMLDFIQEANVYGVAISGYEGRAGMASIILKPNTSLDLEKV 541
DTFRWKGENV+TTEV + L + + VYGV + G EGRAGMA+ + P + DLE+
Sbjct: 507 DTFRWKGENVSTTEVEGTLSRLLDMADVAVYGVEVPGTEGRAGMAA-VASPTGNCDLERF 565
Query: 542 YEQVVTFLPAYACPRFLRIQEKMEATGTFKLLKHQLVEDGFNPLKISEPLYFMDNLKKSY 601
+ + LP YA P FLR+ ++ TGT+K K +L ++GF+P + +PL+++D K Y
Sbjct: 566 AQVLEKELPLYARPIFLRLLPELHKTGTYKFQKTELRKEGFDPAIVKDPLFYLDAQKGRY 625
Query: 602 VLLTRELYDQIMLGEIKL 619
V L +E Y +I GE KL
Sbjct: 626 VPLDQEAYSRIQAGEEKL 643
>gi|38524616 solute carrier family 27, member 1 [Homo sapiens]
Length = 646
Score = 410 bits (1053), Expect = e-114
Identities = 227/603 (37%), Positives = 354/603 (58%), Gaps = 23/603 (3%)
Query: 30 DFWFVLKVVLIIIRLKKYEKRGELVTVLDKFLSHAKRQPRKPFIIYEG--DIYTYQDVDK 87
D + + ++ + + L+++++ G + + F + +RQP + ++ G + +T+ +D
Sbjct: 54 DLFGLSVLIRVRLELRRHQRAGHTIPRI--FQAVVQRQPERLALVDAGTGECWTFAQLDA 111
Query: 88 RSSRVAHVFLNHSSLKKGDTVALLMSNEPDFVHVWFGLAKLGCVVAFLNTNIRSNSLLNC 147
S+ VA++F GD VA+ + P+FV +W GLAK G A LN N+R L C
Sbjct: 112 YSNAVANLF-RQLGFAPGDVVAIFLEGRPEFVGLWLGLAKAGMEAALLNVNLRREPLAFC 170
Query: 148 IRACGPRALVVGADLLGTVEEILPSLSENISVWGMKDSVPQGVIS-------LKEKLSTS 200
+ G +AL+ G +++ V E+ L +++ + D P+G++ L ++ ST+
Sbjct: 171 LGTSGAKALIFGGEMVAAVAEVSGHLGKSLIKFCSGDLGPEGILPDTHLLDPLLKEASTA 230
Query: 201 PDEPVPRSHHVVSLLKSTCLYIFTSGTTGLPKAAVISQLQVLRGSAV-LWAFGCTAHDIV 259
P +P + YI+TSGTTGLPKAA++ + R +A A+ A D++
Sbjct: 231 PLAQIPSKG-----MDDRLFYIYTSGTTGLPKAAIVVHSRYYRMAAFGHHAYRMQAADVL 285
Query: 260 YITLPLYHSSAAILGISGCVELGATCVLKKKFSASQFWSDCKKYDVTVFQYIGELCRYLC 319
Y LPLYHS+ I+G+ C+ G T VL+KKFSAS+FW DC KY+ TV QYIGE+CRYL
Sbjct: 286 YDCLPLYHSAGNIIGVGQCLIYGLTVVLRKKFSASRFWDDCIKYNCTVVQYIGEICRYLL 345
Query: 320 KQSKREGEKDHKVRLAIGNGIRSDVWREFLDRFGNIKVCELYAATESSISFMNYTGRIGA 379
KQ RE E+ H+VRLA+GNG+R +W EF +RFG ++ E Y ATE + S N G++G+
Sbjct: 346 KQPVREAERRHRVRLAVGNGLRPAIWEEFTERFGVRQIGEFYGATECNCSIANMDGKVGS 405
Query: 380 IGRTNLFYKLLSTFDLIKYDFQKDEPMRNEQGWCIHVKKGEPGLLISRVNAKNP---FFG 436
G + + L+K + E +R+ QG CI + GEPGLL+ ++N ++P F G
Sbjct: 406 CGFNSRILPHVYPIRLVKVNEDTMELLRDAQGLCIPCQAGEPGLLVGQINQQDPLRRFDG 465
Query: 437 YAGPYKHTKDKLLCDVFKKGDVYLNTGDLIVQDQDNFLYFWDRTGDTFRWKGENVATTEV 496
Y T K+ VF KGD +GD++V D+ ++YF DR+GDTFRW+GENV+TTEV
Sbjct: 466 YVSE-SATSKKIAHSVFSKGDSAYLSGDVLVMDELGYMYFRDRSGDTFRWRGENVSTTEV 524
Query: 497 ADVIGMLDFIQEANVYGVAISGYEGRAGMASIILKPNTSLDLEKVYEQVVTFLPAYACPR 556
V+ L + VYGVA+ G EG+AGMA+ + P++ LD +Y+++ L YA P
Sbjct: 525 EGVLSRLLGQTDVAVYGVAVPGVEGKAGMAA-VADPHSLLDPNAIYQELQKVLAPYARPI 583
Query: 557 FLRIQEKMEATGTFKLLKHQLVEDGFNPLKISEPLYFMDNLKKSYVLLTRELYDQIMLGE 616
FLR+ +++ TGTFK+ K +L +GF+P + S+ L+F+D + Y+ L +Y +I G
Sbjct: 584 FLRLLPQVDTTGTFKIQKTRLQREGFDPRQTSDRLFFLDLKQGHYLPLNEAVYTRICSGA 643
Query: 617 IKL 619
L
Sbjct: 644 FAL 646
>gi|28416953 acyl-CoA synthetase short-chain family member 1 [Homo
sapiens]
Length = 689
Score = 68.9 bits (167), Expect = 1e-11
Identities = 116/566 (20%), Positives = 218/566 (38%), Gaps = 62/566 (10%)
Query: 51 GELVTVLDKFLSHAKRQPRKPFIIYEGDI------YTYQDVDKRSSRVAHVFLNHSSLKK 104
G+L ++ H ++ P +I+E D TY+++ + + R+A+ H + +
Sbjct: 106 GQLNVSVNCLDQHVRKSPESVALIWERDEPGTEVRITYRELLETTCRLANTLKRHG-VHR 164
Query: 105 GDTVALLMSNEPDFVHVWFGLAKLGCVVAFLNTNIRSNSLLNCIRACGPRALVVG----- 159
GD VA+ M P V A++G V + + SL I + ++
Sbjct: 165 GDRVAIYMPVSPLAVAAMLACARIGAVHTVIFAGFSAESLAGRINDAKCKVVITFNQGLR 224
Query: 160 ----ADLLGTVEEIL---PSLSENISVWGMKDSVPQGVISLKEKLSTSPDEPVPRSHHVV 212
+L V+E + P++ + + V G + + + + ++PV +
Sbjct: 225 GGRVVELKKIVDEAVKHCPTVQHVLVAHRTDNKVHMGDLDVPLEQEMAKEDPVCAPESMG 284
Query: 213 SLLKSTCLYIFTSGTTGLPKAAVISQLQVLRGSAVLW----------AFGCTAHDIVYIT 262
S + ++TSG+TG+PK V +Q L +A+ FGC A DI +IT
Sbjct: 285 S--EDMLFMLYTSGSTGMPKGIVHTQAGYLLYAALTHKLVFDHQPGDIFGCVA-DIGWIT 341
Query: 263 LPLYHSSAAILGISGCVELGATCVLKKKF----SASQFWSDCKKYDVTVFQYIGELCRYL 318
Y + G + GAT VL + +A ++W ++ + F R L
Sbjct: 342 GHSY-------VVYGPLCNGATSVLFESTPVYPNAGRYWETVERLKINQFYGAPTAVRLL 394
Query: 319 CKQS----KREGEKDHKVRLAIGNGIRSDVWREFLDRFGNIKVCELYAATESSISFMNYT 374
K K+ + ++G I + W E+L R C L + T
Sbjct: 395 LKYGDAWVKKYDRSSLRTLGSVGEPINCEAW-EWLHRVVGDSRCTLV-----DTWWQTET 448
Query: 375 GRIGAIGRTNLFYKLLSTFDLIKYDFQKDEPMRNEQGWCIHVKKGEPGLLISRVNAKNPF 434
G I R + + ++ F + +E+G + L IS+ +
Sbjct: 449 GGICIAPRPSEEGAEILPAMAMRPFFGIVPVLMDEKGSVVEGSNVSGALCISQA-----W 503
Query: 435 FGYAGPYKHTKDKLLCDVFKKGDVYLNTGDLIVQDQDNFLYFWDRTGDTFRWKGENVATT 494
G A + + FK Y TGD + + + R D G + T
Sbjct: 504 PGMARTIYGDHQRFVDAYFKAYPGYYFTGDGAYRTEGGYYQITGRMDDVINISGHRLGTA 563
Query: 495 EVADVIGMLDFIQEANVYGVAISGYEGRAGMASIILKP---NTSLDLEKVYEQVVTFLPA 551
E+ D I + E+ V G +G A A I++K ++ + ++++ V T +
Sbjct: 564 EIEDAIADHPAVPESAVIGYP-HDIKGEAAFAFIVVKDSAGDSDVVVQELKSMVATKIAK 622
Query: 552 YACPRFLRIQEKMEATGTFKLLKHQL 577
YA P + + +++ T + K+++ L
Sbjct: 623 YAVPDEILVVKRLPKTRSGKVMRRLL 648
>gi|42544132 SA hypertension-associated homolog isoform 1 [Homo
sapiens]
Length = 586
Score = 67.0 bits (162), Expect = 5e-11
Identities = 108/514 (21%), Positives = 210/514 (40%), Gaps = 46/514 (8%)
Query: 80 YTYQDVDKRSSRVAHVFLNHSSLKKGDTVALLMSNEPDFVHVWFGLAKLGCVVAFLNTNI 139
++++++ S + A++ SL++GD V L++ P++ + G V+ T +
Sbjct: 95 WSFEELGSLSRKFANILSEACSLQRGDRVILILPRVPEWWLANVACLRTGTVLIPGTTQL 154
Query: 140 RSNSLLNCIRACGPRALVVGADLLGTVEEILPSLSENI-SVWGMKDSVPQGVISLKEKLS 198
+L +++ ++ D+L + + S EN+ S + ++ +G +LKE +
Sbjct: 155 TQKDILYRLQSSKANCIITN-DVLAPAVDAVASKCENLHSKLIVSENSREGWGNLKELMK 213
Query: 199 TSPDEPVPRSHHVVSLLKSTCLYIF-TSGTTGLPKAAVISQLQVLRGSAVLWAF--GCTA 255
+ D SH V + + IF TSGT+G PK + G +V F T
Sbjct: 214 HASD-----SHTCVKTKHNEIMAIFFTSGTSGYPKMTAHTHSSFGLGLSVNGRFWLDLTP 268
Query: 256 HDIVYITLPLYHSSAAILGISGCVELGATCVLKK---KFSASQFWSDCKKYDVTVFQYIG 312
D+++ T + +A + GA CV +F + KY +TVF
Sbjct: 269 SDVMWNTSDTGWAKSAWSSVFSPWIQGA-CVFTHHLPRFEPTSILQTLSKYPITVFCSAP 327
Query: 313 ELCRYLCKQSKREGE-KDHKVRLAIGNGIRSDVWREFLDRFGNIKVCELYAATESSISFM 371
+ R L + + K K ++ G I DV ++ ++ G + + E Y TE+ +
Sbjct: 328 TVYRMLVQNDITSYKFKSLKHCVSAGEPITPDVTEKWRNKTG-LDIYEGYGQTETVLICG 386
Query: 372 NYTG---RIGAIGRTNLFYKLLSTFDLIKYDFQKDEPMRNEQGWCIHVKKGEPGLLISRV 428
N+ G + G++G+ + FD+ D + + G+ G + +V
Sbjct: 387 NFKGMKIKPGSMGKPS------PAFDVKIVDVNGNV-----------LPPGQEGDIGIQV 429
Query: 429 NAKNPFFGYAGPYKHTKDKLLCDVFKKGDVYLNTGDLIVQDQDNFLYFWDRTGDTFRWKG 488
PF G Y K + +G+ Y+ TGD D+D + +F R D G
Sbjct: 430 LPNRPF-GLFTHYVDNPSKTASTL--RGNFYI-TGDRGYMDKDGYFWFVARADDVILSSG 485
Query: 489 ENVATTEVADVIGMLDFIQEANVYGVAISGYEGRAGMASIILKPNTSLD-----LEKVYE 543
+ EV + + + E+ V + G A ++L P+ ++++ E
Sbjct: 486 YRIGPFEVENALNEHPSVAESAVVS-SPDPIRGEVVKAFVVLNPDYKSHDQEQLIKEIQE 544
Query: 544 QVVTFLPAYACPRFLRIQEKMEATGTFKLLKHQL 577
V Y PR + +++ T + K +++L
Sbjct: 545 HVKKTTAPYKYPRKVEFIQELPKTISGKTKRNEL 578
>gi|122937307 acyl-CoA synthetase medium-chain family member 4 [Homo
sapiens]
Length = 580
Score = 64.3 bits (155), Expect = 3e-10
Identities = 114/518 (22%), Positives = 203/518 (39%), Gaps = 54/518 (10%)
Query: 80 YTYQDVDKRSSRVAHVFLNHSSLKKGDTVALLMSNEPDFVHVWFGLAKLGCVVAFLNTNI 139
++++++ S + A+V L++GD +A+++ P++ V + G + +
Sbjct: 89 WSFRELGSLSRKAANVLTKPCGLQRGDRLAVILPRIPEWWLVNVACIRTGIIFMPGTIQL 148
Query: 140 RSNSLLNCIRACGPRALVVGADLLGTVEEIL---PSLSENISVWGMKDSVPQ---GVISL 193
+ +L +RA + +V ++ VE I+ P L + V PQ G +S
Sbjct: 149 TAKDILYRLRASKAKCIVASEEVAPAVESIVLECPDLKTKLLV------SPQSWNGWLSF 202
Query: 194 KEKLSTSPDEPVPRSHHVVSLLKSTCLYI-FTSGTTGLPKAAVISQLQVLRGSAVLWAF- 251
+E + +E H V + I FTSGTTG PK A SQ + G + +
Sbjct: 203 QELFQFASEE-----HSCVETGSQEPMTIYFTSGTTGFPKMAQHSQSSLGIGFTLCGRYW 257
Query: 252 -GCTAHDIVYITLPLYHSSAAILGISGCVELGATCVLKK--KFSASQFWSDCKKYDVTVF 308
+ DI++ AAI + GA + + +F F Y +T
Sbjct: 258 LDLKSSDIIWNMSDTGWVKAAIGSVFSSWLCGACVFVHRMAQFDTDTFLDTLTTYPITTL 317
Query: 309 QYIGELCRYLC-KQSKREGEKDHKVRLAIGNGIRSDVWREFLDRFGNIKVCELYAATESS 367
+ R L K KR K + L G + +V ++ + G +++ E Y TE
Sbjct: 318 CSPPTVYRMLVQKDLKRYKFKSLRHCLTGGEPLNPEVLEQWRVQTG-LELYEGYGQTEVG 376
Query: 368 ISFMNYTG---RIGAIGRTNLFYKLLSTFDLIKYDFQKDEPMRNEQGWCIHVKKGEPGLL 424
+ N G + G++G+ ++ YD Q + N + G+ G +
Sbjct: 377 MICANQKGQEIKPGSMGK-----------GMLPYDVQIIDENGNV------LPPGKEGEI 419
Query: 425 ISRVNAKNPFFGYAGPYKHTKDKLLCDVFKKGDVYLNTGDLIVQDQDNFLYFWDRTGDTF 484
R+ PF + Y K + +GD Y+ TGD V D D + +F R D
Sbjct: 420 ALRLKPTRPFC-FFSKYVDNPQKTAATI--RGDFYV-TGDRGVMDSDGYFWFVGRADDVI 475
Query: 485 RWKGENVATTEVADVIGMLDFIQEANVYGVAISGYEGRAGMASIIL-KPNTSLDLEK--- 540
G + EV + + E+ V + G A ++L P S + EK
Sbjct: 476 ISSGYRIGPFEVESALIEHPAVVESAVVS-SPDQIRGEVVKAFVVLAAPFKSYNPEKLTL 534
Query: 541 -VYEQVVTFLPAYACPRFLRIQEKMEATGTFKLLKHQL 577
+ + V Y PR + +++ T T K+ ++ L
Sbjct: 535 ELQDHVKKSTAPYKYPRKVEFVQELPKTITGKIKRNVL 572
>gi|157311624 acyl-CoA synthetase medium-chain family member 2B
[Homo sapiens]
Length = 577
Score = 63.9 bits (154), Expect = 4e-10
Identities = 110/516 (21%), Positives = 207/516 (40%), Gaps = 49/516 (9%)
Query: 79 IYTYQDVDKRSSRVAHVFLNHSSLKKGDTVALLMSNEPDFVHVWFGLAKLGCVVAFLNTN 138
++ ++++ + S + A++ L++GD VA+++ P++ V G + G +
Sbjct: 80 MWNFRELSENSQQAANILSGACGLQRGDRVAVMLPRVPEWWLVILGCIRAGLIFMPGTIQ 139
Query: 139 IRSNSLLNCIRACGPRALVVGADLLGTVEEIL---PSLSENISVWGMKDSVPQGVISLKE 195
++S +L ++ +A+V G +++ V+ + PSL + V + G ++ K+
Sbjct: 140 MKSTDILYRLQMSKAKAIVAGDEVIQEVDTVASECPSLRIKLLV---SEKSCDGWLNFKK 196
Query: 196 KLSTSPDEPVPRSHHVVSL--LKSTCLYIFTSGTTGLPKAAVISQLQV-LRGSAVLWAFG 252
L+ + +HH V +++ +Y FTSGT+GLPK A S + L+ G
Sbjct: 197 LLNEAST-----THHCVETGSQEASAIY-FTSGTSGLPKMAEHSYSSLGLKAKMDAGWTG 250
Query: 253 CTAHDIVYITLPLYHSSAAILGISGCV----ELGATCV--LKKKFSASQFWSDCKKYDVT 306
A DI++ + IL I G + LGA L KF Y +
Sbjct: 251 LQASDIMW----TISDTGWILNILGSLLESWTLGACTFVHLLPKFDPLVILKTLSSYPIK 306
Query: 307 VFQYIGELCRYLCKQSKREGEKDHKVR-LAIGNGIRSDVWREFLDRFGNIKVCELYAATE 365
+ R L +Q + H LA G + + + + G + + E Y TE
Sbjct: 307 SMMGAPIVYRMLLQQDLSSYKFPHLQNCLAGGESLLPETLENWRAQTG-LDIREFYGQTE 365
Query: 366 SSISFMNYTGRIGAIGRTNLFYKLLSTFDLIKYDFQKDEPMRNEQGWCIHVKKGEPGLLI 425
+ ++ M + +T YD Q + N + G G +
Sbjct: 366 TGLTCM--------VSKTMKIKPGYMGTAASCYDVQVIDDKGNV------LPPGTEGDIG 411
Query: 426 SRVNAKNPFFGYAGPYKHTKDKLLCDVFKKGDVYLNTGDLIVQDQDNFLYFWDRTGDTFR 485
RV P ++G Y DK ++ +GD +L GD ++D+D + F R D
Sbjct: 412 IRVKPIRPIGIFSG-YVENPDKTAANI--RGDFWL-LGDRGIKDEDGYFQFMGRADDIIN 467
Query: 486 WKGENVATTEVADVIGMLDFIQEANVYGV--AISGYEGRAG--MASIILKPNTSLDLEKV 541
G + +EV + + + E V + G +A +AS L + +++
Sbjct: 468 SSGYRIGPSEVENALMKHPAVVETAVISSPDPVRGEVVKAFVILASQFLSHDPEQLTKEL 527
Query: 542 YEQVVTFLPAYACPRFLRIQEKMEATGTFKLLKHQL 577
+ V + Y PR + + T T K+ + +L
Sbjct: 528 QQHVKSVTAPYKYPRKIEFVLNLPKTVTGKIQRTKL 563
>gi|157311622 acyl-CoA synthetase medium-chain family member 2B
[Homo sapiens]
Length = 577
Score = 63.9 bits (154), Expect = 4e-10
Identities = 110/516 (21%), Positives = 207/516 (40%), Gaps = 49/516 (9%)
Query: 79 IYTYQDVDKRSSRVAHVFLNHSSLKKGDTVALLMSNEPDFVHVWFGLAKLGCVVAFLNTN 138
++ ++++ + S + A++ L++GD VA+++ P++ V G + G +
Sbjct: 80 MWNFRELSENSQQAANILSGACGLQRGDRVAVMLPRVPEWWLVILGCIRAGLIFMPGTIQ 139
Query: 139 IRSNSLLNCIRACGPRALVVGADLLGTVEEIL---PSLSENISVWGMKDSVPQGVISLKE 195
++S +L ++ +A+V G +++ V+ + PSL + V + G ++ K+
Sbjct: 140 MKSTDILYRLQMSKAKAIVAGDEVIQEVDTVASECPSLRIKLLV---SEKSCDGWLNFKK 196
Query: 196 KLSTSPDEPVPRSHHVVSL--LKSTCLYIFTSGTTGLPKAAVISQLQV-LRGSAVLWAFG 252
L+ + +HH V +++ +Y FTSGT+GLPK A S + L+ G
Sbjct: 197 LLNEAST-----THHCVETGSQEASAIY-FTSGTSGLPKMAEHSYSSLGLKAKMDAGWTG 250
Query: 253 CTAHDIVYITLPLYHSSAAILGISGCV----ELGATCV--LKKKFSASQFWSDCKKYDVT 306
A DI++ + IL I G + LGA L KF Y +
Sbjct: 251 LQASDIMW----TISDTGWILNILGSLLESWTLGACTFVHLLPKFDPLVILKTLSSYPIK 306
Query: 307 VFQYIGELCRYLCKQSKREGEKDHKVR-LAIGNGIRSDVWREFLDRFGNIKVCELYAATE 365
+ R L +Q + H LA G + + + + G + + E Y TE
Sbjct: 307 SMMGAPIVYRMLLQQDLSSYKFPHLQNCLAGGESLLPETLENWRAQTG-LDIREFYGQTE 365
Query: 366 SSISFMNYTGRIGAIGRTNLFYKLLSTFDLIKYDFQKDEPMRNEQGWCIHVKKGEPGLLI 425
+ ++ M + +T YD Q + N + G G +
Sbjct: 366 TGLTCM--------VSKTMKIKPGYMGTAASCYDVQVIDDKGNV------LPPGTEGDIG 411
Query: 426 SRVNAKNPFFGYAGPYKHTKDKLLCDVFKKGDVYLNTGDLIVQDQDNFLYFWDRTGDTFR 485
RV P ++G Y DK ++ +GD +L GD ++D+D + F R D
Sbjct: 412 IRVKPIRPIGIFSG-YVENPDKTAANI--RGDFWL-LGDRGIKDEDGYFQFMGRADDIIN 467
Query: 486 WKGENVATTEVADVIGMLDFIQEANVYGV--AISGYEGRAG--MASIILKPNTSLDLEKV 541
G + +EV + + + E V + G +A +AS L + +++
Sbjct: 468 SSGYRIGPSEVENALMKHPAVVETAVISSPDPVRGEVVKAFVILASQFLSHDPEQLTKEL 527
Query: 542 YEQVVTFLPAYACPRFLRIQEKMEATGTFKLLKHQL 577
+ V + Y PR + + T T K+ + +L
Sbjct: 528 QQHVKSVTAPYKYPRKIEFVLNLPKTVTGKIQRTKL 563
>gi|38505220 acyl-CoA synthetase medium-chain family member 5 [Homo
sapiens]
Length = 579
Score = 62.0 bits (149), Expect = 2e-09
Identities = 114/517 (22%), Positives = 202/517 (39%), Gaps = 53/517 (10%)
Query: 80 YTYQDVDKRSSRVAHVFLNHSSLKKGDTVALLMSNEPDFVHVWFGLAKLGCVVAFLNTNI 139
++++++ K+S + A+V L+ GD + L++ P++ V + G V+ T +
Sbjct: 90 WSFEELGKQSRKAANVLGGACGLQPGDRMMLVLPRLPEWWLVSVACMRTGTVMIPGVTQL 149
Query: 140 RSNSLLNCIRACGPRALVVGADLLGTVEEI---LPSLSENISVWGMKDSVPQGVISLKEK 196
L ++A ++++ L V+ I PSL + V DS G ++ +E
Sbjct: 150 TEKDLKYRLQASRAKSIITSDSLAPRVDAISAECPSLQTKLLV---SDSSRPGWLNFREL 206
Query: 197 LSTSPDEPVPRSHHVVSLLKSTCLYI-FTSGTTGLPKAAVISQLQVLRG---SAVLWAFG 252
L + E H+ + L I FTSGTTG PK SQ G S W
Sbjct: 207 LREASTE-----HNCMRTKSRDPLAIYFTSGTTGAPKMVEHSQSSYGLGFVASGRRWV-A 260
Query: 253 CTAHDIVYITLPLYHSSAAILGISGCVELGATCVL---KKKFSASQFWSDCKKYDVTVFQ 309
T DI + T AA S +C+ + A + K+ +T
Sbjct: 261 LTESDIFWNTTDTGWVKAAWTLFSAWP--NGSCIFVHELPRVDAKVILNTLSKFPITTLC 318
Query: 310 YIGELCRYLCKQS-KREGEKDHKVRLAIGNGIRSDVWREFLDRFGNIKVCELYAATESSI 368
+ + R L ++ R + + L G + DV ++ + G +++ E Y +E+ +
Sbjct: 319 CVPTIFRLLVQEDLTRYQFQSLRHCLTGGEALNPDVREKWKHQTG-VELYEGYGQSETVV 377
Query: 369 SFMNYTG---RIGAIGRTNLFYKLLSTFDLIKYDFQKDEPMRNEQGWCIHVKKGEPGLLI 425
N G + G++G+ + YD Q + N + GE G +
Sbjct: 378 ICANPKGMKIKSGSMGKAS-----------PPYDVQIVDDEGNV------LPPGEEGNVA 420
Query: 426 SRVNAKNPFFGYAGPYKHTKDKLLCDVFKKGDVYLNTGDLIVQDQDNFLYFWDRTGDTFR 485
R+ PF + Y +K ++GD Y+ TGD D+D + +F R D
Sbjct: 421 VRIRPTRPFC-FFNCYLDNPEKTAAS--EQGDFYI-TGDRARMDKDGYFWFMGRNDDVIN 476
Query: 486 WKGENVATTEVADVIGMLDFIQEANVYGVAISGYEGRAGMASIILKP-NTSLDLE----K 540
+ EV + + E+ V + G A I+L P +S D E +
Sbjct: 477 SSSYRIGPVEVESALAEHPAVLESAVVS-SPDPIRGEVVKAFIVLTPAYSSHDPEALTRE 535
Query: 541 VYEQVVTFLPAYACPRFLRIQEKMEATGTFKLLKHQL 577
+ E V Y PR + ++ T + K+ + +L
Sbjct: 536 LQEHVKRVTAPYKYPRKVAFVSELPKTVSGKIQRSKL 572
>gi|115511026 acyl-CoA synthetase medium-chain family member 1 [Homo
sapiens]
Length = 577
Score = 61.6 bits (148), Expect = 2e-09
Identities = 120/557 (21%), Positives = 213/557 (38%), Gaps = 77/557 (13%)
Query: 56 VLDKFLSHAKRQPRKP-----FIIYEGDI--YTYQDVDKRSSRVAHVFLNHSSLKKGDTV 108
VLD + K R P ++ +GD ++++++ + RVA+VF L++GD +
Sbjct: 55 VLDYWAQKEKEGKRGPNPAFWWVNGQGDEVKWSFREMGDLTRRVANVFTQTCGLQQGDHL 114
Query: 109 ALLMSNEPDFVHVWFGLAKLGCVVAFLNTNIRSNSLLNCIRACGPRALVVGADLLGTVEE 168
AL++ P++ V G + G + +++ +L ++ + +V L V+
Sbjct: 115 ALMLPRVPEWWLVAVGCMRTGIIFIPATILLKAKDILYRLQLSKAKGIVTIDALASEVDS 174
Query: 169 I---LPSLSENISVWGMKDSVPQGVISLKEKL-STSPDEPVPRSHHVVSLLKSTCLYIFT 224
I PSL + V D +G + + + S SP+ +S + + FT
Sbjct: 175 IASQCPSLKTKLLV---SDHSREGWLDFRSLVKSASPEHTCVKSKTL-----DPMVIFFT 226
Query: 225 SGTTGLPKAAVIS-------------QLQVLRGSAVLWAFGCTAHDIVYITLPLYHSSAA 271
SGTTG PK A S +L+ L+ S V W + + I + +A
Sbjct: 227 SGTTGFPKMAKHSHGLALQPSFPGSRKLRSLKTSDVSWCLSDSGWIVATIWTLVEPWTA- 285
Query: 272 ILGISGCVELGATCVLK--KKFSASQFWSDCKKYDVTVFQYIGELCRYLCKQSKREGEKD 329
G T + +F KY + F + + R + +Q
Sbjct: 286 ----------GCTVFIHHLPQFDTKVIIQTLLKYPINHFWGVSSIYRMILQQDFTSIRFP 335
Query: 330 HKVRLAIGNGIRSDVWREFLDRFGNIKVCELYAATESSISFMNYTG---RIGAIGRTNLF 386
G + +E R + + E Y +E+ + Y G + G +G+
Sbjct: 336 ALEHCYTGGEVVLPKDQEEWKRRTGLLLYENYGQSETGLICATYWGMKIKPGFMGKATPP 395
Query: 387 YKLLSTFDLIKYDFQKDEPMRNEQGWCIHVK-KGEPGLLISRVNAKNPFFGYAGPYKHTK 445
Y D + +++G + +G G+ I V + F Y G + T
Sbjct: 396 Y---------------DVQVIDDKGSILPPNTEGNIGIRIKPVRPVSLFMCYEGDPEKTA 440
Query: 446 DKLLCDVFKKGDVYLNTGDLIVQDQDNFLYFWDRTGDTFRWKGENVATTEVADVIGMLDF 505
K+ C GD Y NTGD D++ ++ F R+ D G + EV +
Sbjct: 441 -KVEC-----GDFY-NTGDRGKMDEEGYICFLGRSDDIINASGYRIGPAEVESALVEHPA 493
Query: 506 IQEANVYGVAISGYEGRAGMASIILKP----NTSLDLEKVYEQVVTFLPA-YACPRFLRI 560
+ E+ V G + G A I+L P + L K +Q V + A Y PR +
Sbjct: 494 VAESAVVG-SPDPIRGEVVKAFIVLTPQFLSHDKDQLTKELQQHVKSVTAPYKYPRKVEF 552
Query: 561 QEKMEATGTFKLLKHQL 577
++ T T K+ + +L
Sbjct: 553 VSELPKTITGKIERKEL 569
>gi|239756507 PREDICTED: similar to Acyl-coenzyme A synthetase
ACSM2B, mitochondrial isoform 2 [Homo sapiens]
Length = 571
Score = 60.8 bits (146), Expect = 3e-09
Identities = 108/517 (20%), Positives = 207/517 (40%), Gaps = 57/517 (11%)
Query: 79 IYTYQDVDKRSSRVAHVFLNHSSLKKGDTVALLMSNEPDFVHVWFGLAKLGCVVAFLNTN 138
++ ++++ + S + A+V L++GD VA+++ P++ V G + G +
Sbjct: 80 MWNFRELSENSQQAANVLSGACGLQRGDRVAVMLPRVPEWWLVILGCIRAGLIFMPGTIQ 139
Query: 139 IRSNSLLNCIRACGPRALVVGADLLGTVEEIL---PSLSENISVWGMKDSVPQGVISLKE 195
++S +L ++ +A+V G +++ V+ + PSL + V + G ++ K+
Sbjct: 140 MKSTDILYRLQMSKAKAIVAGDEVIQEVDTVASECPSLRIKLLV---SEKSCDGWLNFKK 196
Query: 196 KLSTSPDEPVPRSHHVVSL--LKSTCLYIFTSGTTGLPKAAVISQLQV-LRGSAVLWAFG 252
L+ + +HH V +++ +Y FTSGT+GLPK A S + L+ G
Sbjct: 197 LLNEAST-----THHCVETGSQEASAIY-FTSGTSGLPKMAEHSYSSLGLKAKMDAGWTG 250
Query: 253 CTAHDIVYITLPLYHSSAAILGISGCV----ELGATCV--LKKKFSASQFWSDCKKYDVT 306
A DI++ + IL I G + LGA L KF Y +
Sbjct: 251 LQASDIMW----TISDTGWILNILGSLLESWTLGACTFVHLLPKFDPLVILKTLSSYPIK 306
Query: 307 VFQYIGELCRYLCKQSKREGEKDHKVR-LAIGNGIRSDVWREFLDRFGNIKVCELYAATE 365
+ R L +Q + H LA G + + + + G + + E Y TE
Sbjct: 307 SMMGAPIVYRMLLQQDLSSYKFPHLQNCLAGGESLLPETLENWRAQTG-LDIREFYGQTE 365
Query: 366 SSISFM-NYTGRIGAIGRTNLFYKLLSTFDLIKYDFQKDEPMRNEQGWCIHVKKGEPGLL 424
+ ++ M + T +I + S +D+ F P + G+
Sbjct: 366 TGLTCMVSKTMKI----KPGYMGTAASCYDVQVIAFVHGSPRAGDLGF------------ 409
Query: 425 ISRVNAKNPFFGYAGPYKHTKDKLLCDVFKKGDVYLNTGDLIVQDQDNFLYFWDRTGDTF 484
A + G ++ DK ++ +GD +L GD ++D+D + F R D
Sbjct: 410 -----AGTMTLSFCG-HQENPDKTAANI--RGDFWL-LGDRGIKDEDGYFQFMGRADDII 460
Query: 485 RWKGENVATTEVADVIGMLDFIQEANVYGV--AISGYEGRAG--MASIILKPNTSLDLEK 540
G + +EV + + + E V + G +A +AS L + ++
Sbjct: 461 NSSGYRIGPSEVENALMKHPAVVETAVISSPDPVRGEVVKAFVILASQFLSHDPEQLTKE 520
Query: 541 VYEQVVTFLPAYACPRFLRIQEKMEATGTFKLLKHQL 577
+ + V + Y PR + + T T K+ + +L
Sbjct: 521 LQQHVKSVTAPYKYPRKIEFVLNLPKTVTGKIQRTKL 557
>gi|239756505 PREDICTED: similar to Acyl-coenzyme A synthetase
ACSM2B, mitochondrial isoform 1 [Homo sapiens]
Length = 571
Score = 60.8 bits (146), Expect = 3e-09
Identities = 108/517 (20%), Positives = 207/517 (40%), Gaps = 57/517 (11%)
Query: 79 IYTYQDVDKRSSRVAHVFLNHSSLKKGDTVALLMSNEPDFVHVWFGLAKLGCVVAFLNTN 138
++ ++++ + S + A+V L++GD VA+++ P++ V G + G +
Sbjct: 80 MWNFRELSENSQQAANVLSGACGLQRGDRVAVMLPRVPEWWLVILGCIRAGLIFMPGTIQ 139
Query: 139 IRSNSLLNCIRACGPRALVVGADLLGTVEEIL---PSLSENISVWGMKDSVPQGVISLKE 195
++S +L ++ +A+V G +++ V+ + PSL + V + G ++ K+
Sbjct: 140 MKSTDILYRLQMSKAKAIVAGDEVIQEVDTVASECPSLRIKLLV---SEKSCDGWLNFKK 196
Query: 196 KLSTSPDEPVPRSHHVVSL--LKSTCLYIFTSGTTGLPKAAVISQLQV-LRGSAVLWAFG 252
L+ + +HH V +++ +Y FTSGT+GLPK A S + L+ G
Sbjct: 197 LLNEAST-----THHCVETGSQEASAIY-FTSGTSGLPKMAEHSYSSLGLKAKMDAGWTG 250
Query: 253 CTAHDIVYITLPLYHSSAAILGISGCV----ELGATCV--LKKKFSASQFWSDCKKYDVT 306
A DI++ + IL I G + LGA L KF Y +
Sbjct: 251 LQASDIMW----TISDTGWILNILGSLLESWTLGACTFVHLLPKFDPLVILKTLSSYPIK 306
Query: 307 VFQYIGELCRYLCKQSKREGEKDHKVR-LAIGNGIRSDVWREFLDRFGNIKVCELYAATE 365
+ R L +Q + H LA G + + + + G + + E Y TE
Sbjct: 307 SMMGAPIVYRMLLQQDLSSYKFPHLQNCLAGGESLLPETLENWRAQTG-LDIREFYGQTE 365
Query: 366 SSISFM-NYTGRIGAIGRTNLFYKLLSTFDLIKYDFQKDEPMRNEQGWCIHVKKGEPGLL 424
+ ++ M + T +I + S +D+ F P + G+
Sbjct: 366 TGLTCMVSKTMKI----KPGYMGTAASCYDVQVIAFVHGSPRAGDLGF------------ 409
Query: 425 ISRVNAKNPFFGYAGPYKHTKDKLLCDVFKKGDVYLNTGDLIVQDQDNFLYFWDRTGDTF 484
A + G ++ DK ++ +GD +L GD ++D+D + F R D
Sbjct: 410 -----AGTMTLSFCG-HQENPDKTAANI--RGDFWL-LGDRGIKDEDGYFQFMGRADDII 460
Query: 485 RWKGENVATTEVADVIGMLDFIQEANVYGV--AISGYEGRAG--MASIILKPNTSLDLEK 540
G + +EV + + + E V + G +A +AS L + ++
Sbjct: 461 NSSGYRIGPSEVENALMKHPAVVETAVISSPDPVRGEVVKAFVILASQFLSHDPEQLTKE 520
Query: 541 VYEQVVTFLPAYACPRFLRIQEKMEATGTFKLLKHQL 577
+ + V + Y PR + + T T K+ + +L
Sbjct: 521 LQQHVKSVTAPYKYPRKIEFVLNLPKTVTGKIQRTKL 557
>gi|58082049 acyl-CoA synthetase medium-chain family member 2A [Homo
sapiens]
Length = 577
Score = 60.1 bits (144), Expect = 6e-09
Identities = 90/431 (20%), Positives = 173/431 (40%), Gaps = 37/431 (8%)
Query: 79 IYTYQDVDKRSSRVAHVFLNHSSLKKGDTVALLMSNEPDFVHVWFGLAKLGCVVAFLNTN 138
++ ++++ + S + A+V L++GD VA+++ P++ V G + G +
Sbjct: 80 MWNFRELSENSQQAANVLSGACGLQRGDRVAVVLPRVPEWWLVILGCIRAGLIFMPGTIQ 139
Query: 139 IRSNSLLNCIRACGPRALVVGADLLGTVEEIL---PSLSENISVWGMKDSVPQGVISLKE 195
++S +L ++ +A+V G +++ V+ + PSL + V + G ++ K+
Sbjct: 140 MKSTDILYRLQMSKAKAIVAGDEVIQEVDTVASECPSLRIKLLV---SEKSCDGWLNFKK 196
Query: 196 KLSTSPDEPVPRSHHVVSL--LKSTCLYIFTSGTTGLPKAAVISQLQV-LRGSAVLWAFG 252
L+ + +HH V +++ +Y FTSGT+GLPK A S + L+ G
Sbjct: 197 LLNEAST-----THHCVETGSQEASAIY-FTSGTSGLPKMAEHSYSSLGLKAKMDAGWTG 250
Query: 253 CTAHDIVYITLPLYHSSAAILGISGCVELGATCV--LKKKFSASQFWSDCKKYDVTVFQY 310
A DI++ + + LGA L KF Y +
Sbjct: 251 LQASDIMWTISDTGWILNILCSLMEPWALGACTFVHLLPKFDPLVILKTLSSYPIKSMMG 310
Query: 311 IGELCRYLCKQSKREGEKDHKVR-LAIGNGIRSDVWREFLDRFGNIKVCELYAATESSIS 369
+ R L +Q + H + +G + + + + G + + E Y TE+ ++
Sbjct: 311 APIVYRMLLQQDLSSYKFPHLQNCVTVGESLLPETLENWRAQTG-LDIRESYGQTETGLT 369
Query: 370 FMNYTGRIGAIGRTNLFYKLLSTFDLIKYDFQKDEPMRNEQGWCIHVKKGEPGLLISRVN 429
M + +T YD Q + N + G G + RV
Sbjct: 370 CM--------VSKTMKIKPGYMGTAASCYDVQIIDDKGNV------LPPGTEGDIGIRVK 415
Query: 430 AKNPFFGYAGPYKHTKDKLLCDVFKKGDVYLNTGDLIVQDQDNFLYFWDRTGDTFRWKGE 489
P ++G Y DK ++ +GD +L GD ++D+D + F R D G
Sbjct: 416 PIRPIGIFSG-YVDNPDKTAANI--RGDFWL-LGDRGIKDEDGYFQFMGRADDIINSSGY 471
Query: 490 NVATTEVADVI 500
+ +EV + +
Sbjct: 472 RIGPSEVENAL 482
>gi|187761345 acyl-CoA synthetase family member 3 [Homo sapiens]
Length = 576
Score = 59.7 bits (143), Expect = 8e-09
Identities = 89/399 (22%), Positives = 153/399 (38%), Gaps = 55/399 (13%)
Query: 220 LYIFTSGTTGLPKAAVISQLQ---VLRGSAVLWAFGCTAHDIVYITLPLYHSSAAILGIS 276
+ I+TSGTTG PK + + V+ G WA+ T D++ LPL+H + +
Sbjct: 198 MIIYTSGTTGRPKGVLSTHQNIRAVVTGLVHKWAW--TKDDVILHVLPLHHVHGVVNALL 255
Query: 277 GCVELGATCVLKKKFSASQFWSDCKKYD---VTVFQYIGELCRYLCKQSKREGEKDH--- 330
+ +GATCV+ +FS Q W + + VF + + L + R + H
Sbjct: 256 CPLWVGATCVMMPEFSPQQVWEKFLSSETPRINVFMAVPTIYTKLMEYYDRHFTQPHAQD 315
Query: 331 --------KVRLAIGNGIRSDVWREFLDRFGNI---KVCELYAATESSISF---MNYTGR 376
K+RL + + L+++ NI + E Y TE ++ + R
Sbjct: 316 FLRAVCEEKIRLMVSGSAALPL--PVLEKWKNITGHTLLERYGMTEIGMALSGPLTTAVR 373
Query: 377 I-GAIGRTNLFYKLLSTFDLIKYDFQKDEPMRNEQGWCIHVKKGEPGLLIS--------- 426
+ G++G + ++ + P R + IH + E G ++
Sbjct: 374 LPGSVG---------TPLPGVQVRIVSENPQREACSYTIHAEGDERGTKVTPGFEEKEGE 424
Query: 427 -RVNAKNPFFGYAGPYKHTKDKLLCDVFKKGDVYLNTGDLIVQDQDNFLYFWDRTGDTFR 485
V + F Y + TK D + K TGD +V + + D +
Sbjct: 425 LLVRGPSVFREYWNKPEETKSAFTLDGWFK------TGDTVVFKDGQYWIRGRTSVDIIK 478
Query: 486 WKGENVATTEVADVIGMLDFIQEANVYGVAISGYEGRAGMASIILKPNTSLDLEKVYEQV 545
G V+ EV + I + V GV + G+ A + L+ SL ++ E
Sbjct: 479 TGGYKVSALEVEWHLLAHPSITDVAVIGVPDMTW-GQRVTAVVTLREGHSLSHRELKEWA 537
Query: 546 VTFLPAYACPRFLRIQEKMEATGTFKLLKHQLVEDGFNP 584
L YA P L + E++ K+ K L+ F+P
Sbjct: 538 RNVLAPYAVPSELVLVEEIPRNQMGKIDKKALIRH-FHP 575
>gi|187761343 acyl-CoA synthetase family member 3 [Homo sapiens]
Length = 576
Score = 59.7 bits (143), Expect = 8e-09
Identities = 89/399 (22%), Positives = 153/399 (38%), Gaps = 55/399 (13%)
Query: 220 LYIFTSGTTGLPKAAVISQLQ---VLRGSAVLWAFGCTAHDIVYITLPLYHSSAAILGIS 276
+ I+TSGTTG PK + + V+ G WA+ T D++ LPL+H + +
Sbjct: 198 MIIYTSGTTGRPKGVLSTHQNIRAVVTGLVHKWAW--TKDDVILHVLPLHHVHGVVNALL 255
Query: 277 GCVELGATCVLKKKFSASQFWSDCKKYD---VTVFQYIGELCRYLCKQSKREGEKDH--- 330
+ +GATCV+ +FS Q W + + VF + + L + R + H
Sbjct: 256 CPLWVGATCVMMPEFSPQQVWEKFLSSETPRINVFMAVPTIYTKLMEYYDRHFTQPHAQD 315
Query: 331 --------KVRLAIGNGIRSDVWREFLDRFGNI---KVCELYAATESSISF---MNYTGR 376
K+RL + + L+++ NI + E Y TE ++ + R
Sbjct: 316 FLRAVCEEKIRLMVSGSAALPL--PVLEKWKNITGHTLLERYGMTEIGMALSGPLTTAVR 373
Query: 377 I-GAIGRTNLFYKLLSTFDLIKYDFQKDEPMRNEQGWCIHVKKGEPGLLIS--------- 426
+ G++G + ++ + P R + IH + E G ++
Sbjct: 374 LPGSVG---------TPLPGVQVRIVSENPQREACSYTIHAEGDERGTKVTPGFEEKEGE 424
Query: 427 -RVNAKNPFFGYAGPYKHTKDKLLCDVFKKGDVYLNTGDLIVQDQDNFLYFWDRTGDTFR 485
V + F Y + TK D + K TGD +V + + D +
Sbjct: 425 LLVRGPSVFREYWNKPEETKSAFTLDGWFK------TGDTVVFKDGQYWIRGRTSVDIIK 478
Query: 486 WKGENVATTEVADVIGMLDFIQEANVYGVAISGYEGRAGMASIILKPNTSLDLEKVYEQV 545
G V+ EV + I + V GV + G+ A + L+ SL ++ E
Sbjct: 479 TGGYKVSALEVEWHLLAHPSITDVAVIGVPDMTW-GQRVTAVVTLREGHSLSHRELKEWA 537
Query: 546 VTFLPAYACPRFLRIQEKMEATGTFKLLKHQLVEDGFNP 584
L YA P L + E++ K+ K L+ F+P
Sbjct: 538 RNVLAPYAVPSELVLVEEIPRNQMGKIDKKALIRH-FHP 575
>gi|13375727 acyl-CoA synthetase short-chain family member 3 [Homo
sapiens]
Length = 686
Score = 57.8 bits (138), Expect = 3e-08
Identities = 52/200 (26%), Positives = 93/200 (46%), Gaps = 27/200 (13%)
Query: 57 LDKFLSHAKRQPRKPFIIYEGDI------YTYQDVDKRSSRVAHVFLNHSSLKKGDTVAL 110
+D+ + + K K IIY+ + +TY++V ++ S++A V + H +KKGDTV +
Sbjct: 117 VDRHIENGKGD--KIAIIYDSPVTNTKATFTYKEVLEQVSKLAGVLVKHG-IKKGDTVVI 173
Query: 111 LMSNEPDFVHVWFGLAKLGCVVAFLNTNIRSNSLLNCIRACGPRALVVGADLL--GTVEE 168
M P ++ A++G + + + S L + I P+ +V + + G E
Sbjct: 174 YMPMIPQAMYTMLACARIGAIHSLIFGGFASKELSSRIDHVKPKVVVTASFGIEPGRRVE 233
Query: 169 ILPSLSENISVWGMK------------DSVPQGVISLKEKLSTSPDEPVPRSHHVVSLLK 216
+P + E + + K ++VP ++ L + +SH V +L
Sbjct: 234 YVPLVEEALKIGQHKPDKILIYNRPNMEAVP---LAPGRDLDWDEEMAKAQSHDCVPVLS 290
Query: 217 STCLYI-FTSGTTGLPKAAV 235
LYI +TSGTTGLPK +
Sbjct: 291 EHPLYILYTSGTTGLPKGVI 310
Score = 33.1 bits (74), Expect = 0.78
Identities = 23/98 (23%), Positives = 42/98 (42%), Gaps = 9/98 (9%)
Query: 453 FKKGDVYLNTGDLIVQDQDNFLYFWDRTGDTFRWKGENVATTEVADVIGMLDFIQEANVY 512
F+K Y +T D D++ +LY R D G ++ + + I + V
Sbjct: 528 FEKFPGYYDTMDAGYMDEEGYLYVMSRVDDVINVAGHRISAGAIEESI-----LSHGTVA 582
Query: 513 GVAISGYE----GRAGMASIILKPNTSLDLEKVYEQVV 546
A+ G E G +A +L+ + + E+V E++V
Sbjct: 583 DCAVVGKEDPLKGHVPLALCVLRKDINATEEQVLEEIV 620
>gi|42544134 SA hypertension-associated homolog isoform 2 [Homo
sapiens]
Length = 438
Score = 53.5 bits (127), Expect = 6e-07
Identities = 70/314 (22%), Positives = 137/314 (43%), Gaps = 19/314 (6%)
Query: 80 YTYQDVDKRSSRVAHVFLNHSSLKKGDTVALLMSNEPDFVHVWFGLAKLGCVVAFLNTNI 139
++++++ S + A++ SL++GD V L++ P++ + G V+ T +
Sbjct: 95 WSFEELGSLSRKFANILSEACSLQRGDRVILILPRVPEWWLANVACLRTGTVLIPGTTQL 154
Query: 140 RSNSLLNCIRACGPRALVVGADLLGTVEEILPSLSENI-SVWGMKDSVPQGVISLKEKLS 198
+L +++ ++ D+L + + S EN+ S + ++ +G +LKE +
Sbjct: 155 TQKDILYRLQSSKANCIITN-DVLAPAVDAVASKCENLHSKLIVSENSREGWGNLKELMK 213
Query: 199 TSPDEPVPRSHHVVSLLKSTCLYIF-TSGTTGLPKAAVISQLQVLRGSAVLWAF--GCTA 255
+ D SH V + + IF TSGT+G PK + G +V F T
Sbjct: 214 HASD-----SHTCVKTKHNEIMAIFFTSGTSGYPKMTAHTHSSFGLGLSVNGRFWLDLTP 268
Query: 256 HDIVYITLPLYHSSAAILGISGCVELGATCVLK---KKFSASQFWSDCKKYDVTVFQYIG 312
D+++ T + +A + GA CV +F + KY +TVF
Sbjct: 269 SDVMWNTSDTGWAKSAWSSVFSPWIQGA-CVFTHHLPRFEPTSILQTLSKYPITVFCSAP 327
Query: 313 ELCRYLCKQSKREGE-KDHKVRLAIGNGIRSDVWREFLDRFGNIKVCELYAATESSISFM 371
+ R L + + K K ++ G I DV ++ ++ G + + E Y TE+ +
Sbjct: 328 TVYRMLVQNDITSYKFKSLKHCVSAGEPITPDVTEKWRNKTG-LDIYEGYGQTETVLICG 386
Query: 372 NYTG---RIGAIGR 382
N+ G + G++G+
Sbjct: 387 NFKGMKIKPGSMGK 400
>gi|8923896 acyl-CoA synthetase short-chain family member 2 isoform
1 [Homo sapiens]
Length = 701
Score = 50.1 bits (118), Expect = 6e-06
Identities = 111/517 (21%), Positives = 184/517 (35%), Gaps = 81/517 (15%)
Query: 56 VLDKFLSHAKRQPRKPFIIYEGDI------YTYQDVDKRSSRVAHVFLNHSSLKKGDTVA 109
VLD+ + H K+ K +EG+ TY + + + ++V L ++KGD VA
Sbjct: 107 VLDRNV-HEKKLGDKVAFYWEGNEPGETTQITYHQLLVQVCQFSNV-LRKQGIQKGDRVA 164
Query: 110 LLMSNEPDFVHVWFGLAKLGCVVAFLNTNIRSNSLLNCI--RACGPRALVVGADLLGTVE 167
+ M P+ V A++G + + + S SL I +C +L++ D E
Sbjct: 165 IYMPMIPELVVAMLACARIGALHSIVFAGFSSESLCERILDSSC---SLLITTDAFYRGE 221
Query: 168 EI--LPSLSENISVWGMKDSVPQGVISLKEKL---------STSPDEPVPRS-------- 208
++ L L++ + P + + L STS P+ RS
Sbjct: 222 KLVNLKELADEALQKCQEKGFPVRCCIVVKHLGRAELGMGDSTSQSPPIKRSCPDVQISW 281
Query: 209 --------HHVVSLLKSTC-----------LYIFTSGTTGLPKAAV--ISQLQVLRGSAV 247
H ++ C ++TSG+TG PK V + + +
Sbjct: 282 NQGIDLWWHELMQEAGDECEPEWCDAEDPLFILYTSGSTGKPKGVVHTVGGYMLYVATTF 341
Query: 248 LWAFGCTAHDIVYITLPLYHSSAAILGISGCVELGATCVLKKKF----SASQFWSDCKKY 303
+ F A D+ + T + + G + GAT VL + ++ WS KY
Sbjct: 342 KYVFDFHAEDVFWCTADIGWITGHSYVTYGPLANGATSVLFEGIPTYPDVNRLWSIVDKY 401
Query: 304 DVTVFQYIGELCRYLCKQSKREGEKDHKVRL----AIGNGIRSDVWREFLDRFG--NIKV 357
VT F R L K K + L +G I + W + G +
Sbjct: 402 KVTKFYTAPTAIRLLMKFGDEPVTKHSRASLQVLGTVGEPINPEAWLWYHRVVGAQRCPI 461
Query: 358 CELYAATESSISFMNYTGRIGAIGRTNLFYKLLSTFDLIKYDFQKDEPMRNEQGWCIHVK 417
+ + TE+ + + +TF F + NE G
Sbjct: 462 VDTFWQTETGGHMLT------PLPGATPMKPGSATFPF----FGVAPAILNESG---EEL 508
Query: 418 KGE-PGLLISRVNAKNPFFGYAGPYKHTKDKLLCDVFKKGDVYLNTGDLIVQDQDNFLYF 476
+GE G L+ K P+ G ++ FKK Y TGD +DQD + +
Sbjct: 509 EGEAEGYLV----FKQPWPGIMRTVYGNHERFETTYFKKFPGYYVTGDGCQRDQDGYYWI 564
Query: 477 WDRTGDTFRWKGENVATTEVADVIGMLDFIQEANVYG 513
R D G ++T EV + + + EA V G
Sbjct: 565 TGRIDDMLNVSGHLLSTAEVESALVEHEAVAEAAVVG 601
>gi|253970489 acyl-CoA synthetase short-chain family member 2
isoform 2 [Homo sapiens]
Length = 714
Score = 45.1 bits (105), Expect = 2e-04
Identities = 111/530 (20%), Positives = 184/530 (34%), Gaps = 94/530 (17%)
Query: 56 VLDKFLSHAKRQPRKPFIIYEGDI------YTYQDVDKRSSRVAHVFLNHSSLKKGDTVA 109
VLD+ + H K+ K +EG+ TY + + + ++V L ++KGD VA
Sbjct: 107 VLDRNV-HEKKLGDKVAFYWEGNEPGETTQITYHQLLVQVCQFSNV-LRKQGIQKGDRVA 164
Query: 110 LLMSNEPDFVHVWFGLAKLGCVVAFLNTNIRSNSLLNCI--RACGPRALVVGADLLGTVE 167
+ M P+ V A++G + + + S SL I +C +L++ D E
Sbjct: 165 IYMPMIPELVVAMLACARIGALHSIVFAGFSSESLCERILDSSC---SLLITTDAFYRGE 221
Query: 168 EI--LPSLSENISVWGMKDSVPQGVISLKEKL---------STSPDEPVPRS-------- 208
++ L L++ + P + + L STS P+ RS
Sbjct: 222 KLVNLKELADEALQKCQEKGFPVRCCIVVKHLGRAELGMGDSTSQSPPIKRSCPDVQGKL 281
Query: 209 ---------------------HHVVSLLKSTC-----------LYIFTSGTTGLPKAAV- 235
H ++ C ++TSG+TG PK V
Sbjct: 282 KEKSKRVQPQISWNQGIDLWWHELMQEAGDECEPEWCDAEDPLFILYTSGSTGKPKGVVH 341
Query: 236 -ISQLQVLRGSAVLWAFGCTAHDIVYITLPLYHSSAAILGISGCVELGATCVLKKKF--- 291
+ + + + F A D+ + T + + G + GAT VL +
Sbjct: 342 TVGGYMLYVATTFKYVFDFHAEDVFWCTADIGWITGHSYVTYGPLANGATSVLFEGIPTY 401
Query: 292 -SASQFWSDCKKYDVTVFQYIGELCRYLCKQSKREGEKDHKVRL----AIGNGIRSDVWR 346
++ WS KY VT F R L K K + L +G I + W
Sbjct: 402 PDVNRLWSIVDKYKVTKFYTAPTAIRLLMKFGDEPVTKHSRASLQVLGTVGEPINPEAWL 461
Query: 347 EFLDRFG--NIKVCELYAATESSISFMNYTGRIGAIGRTNLFYKLLSTFDLIKYDFQKDE 404
+ G + + + TE+ + + +TF F
Sbjct: 462 WYHRVVGAQRCPIVDTFWQTETGGHMLT------PLPGATPMKPGSATFPF----FGVAP 511
Query: 405 PMRNEQGWCIHVKKGE-PGLLISRVNAKNPFFGYAGPYKHTKDKLLCDVFKKGDVYLNTG 463
+ NE G +GE G L+ K P+ G ++ FKK Y TG
Sbjct: 512 AILNESG---EELEGEAEGYLV----FKQPWPGIMRTVYGNHERFETTYFKKFPGYYVTG 564
Query: 464 DLIVQDQDNFLYFWDRTGDTFRWKGENVATTEVADVIGMLDFIQEANVYG 513
D +DQD + + R D G ++T EV + + + EA V G
Sbjct: 565 DGCQRDQDGYYWITGRIDDMLNVSGHLLSTAEVESALVEHEAVAEAAVVG 614
>gi|156151445 acyl-CoA synthetase family member 2 [Homo sapiens]
Length = 615
Score = 42.4 bits (98), Expect = 0.001
Identities = 53/232 (22%), Positives = 95/232 (40%), Gaps = 34/232 (14%)
Query: 83 QDVDKRSSRVAHVFLNHSSLKKGDTVALLMSNEPDFVHVWFGLAKLGCVVAFLNTNIRSN 142
++VDK +S + + L KGD + + N +V + A+ G ++ +N ++
Sbjct: 107 EEVDKAASGLLSI-----GLCKGDRLGMWGPNSYAWVLMQLATAQAGIILVSVNPAYQAM 161
Query: 143 SLLNCIRACGPRALVVGADL-----LGTVEEILPSLSENISVWGMK-------------D 184
L ++ G +ALV +++I P + EN +K D
Sbjct: 162 ELEYVLKKVGCKALVFPKQFKTQQYYNVLKQICPEV-ENAQPGALKSQRLPDLTTVISVD 220
Query: 185 SVPQGVISLKEKLST-SPDEPVPRSHHVVSLLK--STCLYIFTSGTTGLPKAAVISQLQV 241
+ G + L E ++ S + + + + L FTSGTTG PK A +S +
Sbjct: 221 APLPGTLLLDEVVAAGSTRQHLDQLQYNQQFLSCHDPINIQFTSGTTGSPKGATLSHYNI 280
Query: 242 LRGSAVLWAFGCTAHD------IVYITLPLYHSSAAILGISGCVELGATCVL 287
+ S +L H+ + + PLYH ++ G C+ GAT +L
Sbjct: 281 VNNSNIL-GERLKLHEKTPEQLRMILPNPLYHCLGSVAGTMMCLMYGATLIL 331
Score = 32.0 bits (71), Expect = 1.7
Identities = 29/123 (23%), Positives = 48/123 (39%), Gaps = 1/123 (0%)
Query: 457 DVYLNTGDLIVQDQDNFLYFWDRTGDTFRWKGENVATTEVADVIGMLDFIQEANVYGVAI 516
D + TGD+ ++ F R+ D GEN+ E+ D +QE V GV
Sbjct: 486 DKWYWTGDVATMNEQGFCKIVGRSKDMIIRGGENIYPAELEDFFHTHPKVQEVQVVGVK- 544
Query: 517 SGYEGRAGMASIILKPNTSLDLEKVYEQVVTFLPAYACPRFLRIQEKMEATGTFKLLKHQ 576
G A I LK +E++ + + P+++ T + K+ K +
Sbjct: 545 DDRMGEEICACIRLKDGEETTVEEIKAFCKGKISHFKIPKYIVFVTNYPLTISGKIQKFK 604
Query: 577 LVE 579
L E
Sbjct: 605 LRE 607
>gi|195947378 acyl-coenzyme A synthetase ACSM6, mitochondrial [Homo
sapiens]
Length = 480
Score = 42.0 bits (97), Expect = 0.002
Identities = 81/428 (18%), Positives = 160/428 (37%), Gaps = 41/428 (9%)
Query: 76 EGDIYTYQDVDKRSSRVAHVFLNHSSLKKGDTVALLMSNEPDFVHVWFGLAKLGCVVAFL 135
E D ++++ + + S + A + + +L GD + +++ P+ + +LG
Sbjct: 82 EEDKWSFERMTQLSKKAASILSDTCALSHGDRLMIILPPTPEAYWICLACVRLGITFVPG 141
Query: 136 NTNIRSNSLLNCIRACGPRALVVG---ADLLGTVEEILPSLSENISVWGMKDSVPQGVIS 192
+ + + + +R + +V A ++ + P+L + V D G +
Sbjct: 142 SPQLTAKKIRYQLRMSKAQCIVANEAMAPVVNSAVSDCPTLKTKLLV---SDKSYDGWLD 198
Query: 193 LKEKLSTSPDEPVPRSHHVVSLLKSTCLYIFTSGTTGLPKAAVISQLQVLRG---SAVLW 249
K+ + +P P+ ++ + + FT GTTG PK SQ + G ++ W
Sbjct: 199 FKKLIQVAP----PKQTYMRTKSQDPMAIFFTKGTTGAPKMVEYSQYGLGMGFSQASRRW 254
Query: 250 AFGCTAHDIVYITLPLYHSSAAILGISGCVELGATCVL--KKKFSASQFWSDCKKYDVTV 307
D+++ + S ++ + G GA L F + ++ +T
Sbjct: 255 -MDLQPTDVLWSLGDAFGGSLSLSAVLGTWFQGACVFLCHMPTFCPETVLNVLSRFPITT 313
Query: 308 F----QYIGELCRYLCKQSKREGEKDHKVRLAIGNGIRSDVWREFLDRFGNIKVCELYAA 363
+ EL ++ C S R K K +A G I V ++ R + + E Y
Sbjct: 314 LSANPEMYQELLQHKCFTSYR--FKSLKQCVAAGGPISPGVIEDW-KRITKLDIYEGYGQ 370
Query: 364 TESSISFMNYTGRIGAIGRTNLFYKLLSTFDLIKYDFQKDEPMRNEQGWCIHVKKGEPGL 423
TE TG + A +T L Y Q + N + GE G
Sbjct: 371 TE--------TGLLCATSKTIKLKPSSLGKPLPPYIVQIVDENSN------LLPPGEEGN 416
Query: 424 LISRVNAKNPFFGYAGPYKHTKDKLLCDVFKKGDVYLNTGDLIVQDQDNFLYFWDRTGDT 483
+ R+ P Y P+ + ++ +G + TGD + D+D + ++ R D
Sbjct: 417 IAIRIKLNQPASLYC-PHMVSWEEY---ASARGHMLYLTGDRGIMDEDGYFWWSGRVDDV 472
Query: 484 FRWKGENV 491
G+ +
Sbjct: 473 ANALGQRL 480
>gi|27477105 lipidosin [Homo sapiens]
Length = 724
Score = 40.0 bits (92), Expect = 0.006
Identities = 51/210 (24%), Positives = 84/210 (40%), Gaps = 24/210 (11%)
Query: 91 RVAHVFLNHSSLKKGDTVALLMSNEPDFVHVWFGLAKLGCVVAFLNTNIRSNSLLNCIRA 150
R A FL LK+ +VA+L N P++ G G +V + T +
Sbjct: 144 RAAKGFLK-LGLKQAHSVAILGFNSPEWFFSAVGTVFAGGIVTGIYTTSSPEACQYIAYD 202
Query: 151 CGPRALVVGADL-LGTVEEILPSLSENISVWGMKDSVPQ---GVISLKEKLSTSPDEPVP 206
C ++V L + +I L +V K+ P V +++E + + P
Sbjct: 203 CCANVIMVDTQKQLEKILKIWKQLPHLKAVVIYKEPPPNKMANVYTMEEFMELGNEVPEE 262
Query: 207 RSHHVVSLLKST--CLYIFTSGTTGLPKAAVISQLQVLRGSAVLWA--FGCTAHDI---- 258
++ + C+ ++TSGTTG PK ++SQ + W +G A DI
Sbjct: 263 ALDAIIDTQQPNQCCVLVYTSGTTGNPKGVMLSQ------DNITWTARYGSQAGDIRPAE 316
Query: 259 -----VYITLPLYHSSAAILGISGCVELGA 283
V LPL H +A I + ++ GA
Sbjct: 317 VQQEVVVSYLPLSHIAAQIYDLWTGIQWGA 346
Score = 29.6 bits (65), Expect = 8.6
Identities = 31/115 (26%), Positives = 52/115 (45%), Gaps = 15/115 (13%)
Query: 441 YKHTKDKLLCDVFKKGDVYLNTGDLIVQDQDNFLYFWDRTGD-TFRWKGENVATTEVADV 499
Y + +DK + ++G +L+TGD D D FLY R + GENV + +
Sbjct: 529 YLNMEDKTCEAIDEEG--WLHTGDAGRLDADGFLYITGRLKELIITAGGENVPPVPIEEA 586
Query: 500 IGM-LDFIQEANVYGVAISGYEGRAGMASII-----LKPNTSLDLEKVYEQVVTF 548
+ M L I A + G + R ++ ++ L P+TS + + EQ + F
Sbjct: 587 VKMELPIISNAMLIG------DQRKFLSMLLTLKCTLDPDTSDQTDNLTEQAMEF 635
>gi|42794760 acyl-CoA synthetase long-chain family member 5 isoform
b [Homo sapiens]
Length = 683
Score = 37.4 bits (85), Expect = 0.041
Identities = 50/224 (22%), Positives = 90/224 (40%), Gaps = 33/224 (14%)
Query: 66 RQPRKPFIIYEGDIYTYQDVDKRSSRVAHVFLNHSSLKKGDT-VALLMSNEPDFVHVWFG 124
R+P +P+ +Y+ V R+ + L+ D V + N P+++
Sbjct: 97 RKPNQPY-----RWLSYKQVSDRAEYLGSCLLHKGYKSSPDQFVGIFAQNRPEWIISELA 151
Query: 125 LAKLGCVVAFLNTNIRSNSLLNCIRACGPRALVVGAD-----LLGTVEE-ILPSLSENIS 178
V L + ++++ + ++ L+G VE+ PSL I
Sbjct: 152 CYTYSMVAVPLYDTLGPEAIVHIVNKADIAMVICDTPQKALVLIGNVEKGFTPSLKVIIL 211
Query: 179 VWGMKDSVPQG-------VISLKEKLSTSPD---EPVPRSHHVVSLLKSTCLYIFTSGTT 228
+ D + Q ++SL + + + +PVP S +S++ FTSGTT
Sbjct: 212 MDPFDDDLKQRGEKSGIEILSLYDAENLGKEHFRKPVPPSPEDLSVI------CFTSGTT 265
Query: 229 GLPKAAVISQLQVLRGSA-----VLWAFGCTAHDIVYITLPLYH 267
G PK A+I+ ++ +A V A+ T D+ LPL H
Sbjct: 266 GDPKGAMITHQNIVSNAAAFLKCVEHAYEPTPDDVAISYLPLAH 309
>gi|42794758 acyl-CoA synthetase long-chain family member 5 isoform
b [Homo sapiens]
Length = 683
Score = 37.4 bits (85), Expect = 0.041
Identities = 50/224 (22%), Positives = 90/224 (40%), Gaps = 33/224 (14%)
Query: 66 RQPRKPFIIYEGDIYTYQDVDKRSSRVAHVFLNHSSLKKGDT-VALLMSNEPDFVHVWFG 124
R+P +P+ +Y+ V R+ + L+ D V + N P+++
Sbjct: 97 RKPNQPY-----RWLSYKQVSDRAEYLGSCLLHKGYKSSPDQFVGIFAQNRPEWIISELA 151
Query: 125 LAKLGCVVAFLNTNIRSNSLLNCIRACGPRALVVGAD-----LLGTVEE-ILPSLSENIS 178
V L + ++++ + ++ L+G VE+ PSL I
Sbjct: 152 CYTYSMVAVPLYDTLGPEAIVHIVNKADIAMVICDTPQKALVLIGNVEKGFTPSLKVIIL 211
Query: 179 VWGMKDSVPQG-------VISLKEKLSTSPD---EPVPRSHHVVSLLKSTCLYIFTSGTT 228
+ D + Q ++SL + + + +PVP S +S++ FTSGTT
Sbjct: 212 MDPFDDDLKQRGEKSGIEILSLYDAENLGKEHFRKPVPPSPEDLSVI------CFTSGTT 265
Query: 229 GLPKAAVISQLQVLRGSA-----VLWAFGCTAHDIVYITLPLYH 267
G PK A+I+ ++ +A V A+ T D+ LPL H
Sbjct: 266 GDPKGAMITHQNIVSNAAAFLKCVEHAYEPTPDDVAISYLPLAH 309
>gi|42794756 acyl-CoA synthetase long-chain family member 5 isoform
a [Homo sapiens]
Length = 739
Score = 37.4 bits (85), Expect = 0.041
Identities = 50/224 (22%), Positives = 90/224 (40%), Gaps = 33/224 (14%)
Query: 66 RQPRKPFIIYEGDIYTYQDVDKRSSRVAHVFLNHSSLKKGDT-VALLMSNEPDFVHVWFG 124
R+P +P+ +Y+ V R+ + L+ D V + N P+++
Sbjct: 153 RKPNQPY-----RWLSYKQVSDRAEYLGSCLLHKGYKSSPDQFVGIFAQNRPEWIISELA 207
Query: 125 LAKLGCVVAFLNTNIRSNSLLNCIRACGPRALVVGAD-----LLGTVEE-ILPSLSENIS 178
V L + ++++ + ++ L+G VE+ PSL I
Sbjct: 208 CYTYSMVAVPLYDTLGPEAIVHIVNKADIAMVICDTPQKALVLIGNVEKGFTPSLKVIIL 267
Query: 179 VWGMKDSVPQG-------VISLKEKLSTSPD---EPVPRSHHVVSLLKSTCLYIFTSGTT 228
+ D + Q ++SL + + + +PVP S +S++ FTSGTT
Sbjct: 268 MDPFDDDLKQRGEKSGIEILSLYDAENLGKEHFRKPVPPSPEDLSVI------CFTSGTT 321
Query: 229 GLPKAAVISQLQVLRGSA-----VLWAFGCTAHDIVYITLPLYH 267
G PK A+I+ ++ +A V A+ T D+ LPL H
Sbjct: 322 GDPKGAMITHQNIVSNAAAFLKCVEHAYEPTPDDVAISYLPLAH 365
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.323 0.140 0.429
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,207,007
Number of Sequences: 37866
Number of extensions: 961339
Number of successful extensions: 2096
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 24
Number of HSP's successfully gapped in prelim test: 27
Number of HSP's that attempted gapping in prelim test: 2031
Number of HSP's gapped (non-prelim): 69
length of query: 619
length of database: 18,247,518
effective HSP length: 108
effective length of query: 511
effective length of database: 14,157,990
effective search space: 7234732890
effective search space used: 7234732890
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.