Guide to the Human Genome
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Search of human proteins with 4826675

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4826675 cyclin-dependent kinase 5 [Homo sapiens]
         (292 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4826675 cyclin-dependent kinase 5 [Homo sapiens]                   603   e-173
gi|4557439 cyclin-dependent kinase 3 [Homo sapiens]                   362   e-100
gi|16936528 cyclin-dependent kinase 2 isoform 1 [Homo sapiens]        350   8e-97
gi|197333744 PCTAIRE protein kinase 1 isoform 2 [Homo sapiens]        339   2e-93
gi|5453860 PCTAIRE protein kinase 1 isoform 1 [Homo sapiens]          339   2e-93
gi|37595545 PCTAIRE protein kinase 2 [Homo sapiens]                   338   3e-93
gi|47078233 PCTAIRE protein kinase 3 isoform a [Homo sapiens]         329   2e-90
gi|47078231 PCTAIRE protein kinase 3 isoform b [Homo sapiens]         329   2e-90
gi|47078229 PCTAIRE protein kinase 3 isoform b [Homo sapiens]         329   2e-90
gi|4502709 cell division cycle 2 isoform 1 [Homo sapiens]             326   1e-89
gi|195927041 cell division cycle 2 isoform 3 [Homo sapiens]           324   5e-89
gi|6912584 PFTAIRE protein kinase 1 [Homo sapiens]                    305   3e-83
gi|21040235 PFTAIRE protein kinase 2 [Homo sapiens]                   286   1e-77
gi|166362719 cyclin-dependent kinase 2 isoform 2 [Homo sapiens]       284   7e-77
gi|4502743 cyclin-dependent kinase 7 [Homo sapiens]                   258   3e-69
gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens]    240   1e-63
gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens]    240   1e-63
gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isof...   240   1e-63
gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isof...   240   1e-63
gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isof...   240   1e-63
gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isof...   240   1e-63
gi|16332360 cell division cycle 2-like 1 (PITSLRE proteins) isof...   240   1e-63
gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isof...   240   1e-63
gi|223718134 cyclin-dependent kinase 6 [Homo sapiens]                 239   3e-63
gi|4502741 cyclin-dependent kinase 6 [Homo sapiens]                   239   3e-63
gi|148596926 cyclin-dependent kinase 10 isoform a [Homo sapiens]      239   3e-63
gi|89903018 cell cycle related kinase isoform 3 [Homo sapiens]        237   8e-63
gi|157817073 Cdc2-related kinase, arginine/serine-rich isoform 2...   224   7e-59
gi|157817023 Cdc2-related kinase, arginine/serine-rich isoform 1...   224   7e-59
gi|4502735 cyclin-dependent kinase 4 [Homo sapiens]                   224   9e-59

>gi|4826675 cyclin-dependent kinase 5 [Homo sapiens]
          Length = 292

 Score =  603 bits (1555), Expect = e-173
 Identities = 292/292 (100%), Positives = 292/292 (100%)

Query: 1   MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKH 60
           MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKH
Sbjct: 1   MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKH 60

Query: 61  KNIVRLHDVLHSDKKLTLVFEFCDQDLKKYFDSCNGDLDPEIVKSFLFQLLKGLGFCHSR 120
           KNIVRLHDVLHSDKKLTLVFEFCDQDLKKYFDSCNGDLDPEIVKSFLFQLLKGLGFCHSR
Sbjct: 61  KNIVRLHDVLHSDKKLTLVFEFCDQDLKKYFDSCNGDLDPEIVKSFLFQLLKGLGFCHSR 120

Query: 121 NVLHRDLKPQNLLINRNGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPDVLFGAKLYS 180
           NVLHRDLKPQNLLINRNGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPDVLFGAKLYS
Sbjct: 121 NVLHRDLKPQNLLINRNGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPDVLFGAKLYS 180

Query: 181 TSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIFRLLGTPTEEQWPSMTKLPDYKPYP 240
           TSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIFRLLGTPTEEQWPSMTKLPDYKPYP
Sbjct: 181 TSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIFRLLGTPTEEQWPSMTKLPDYKPYP 240

Query: 241 MYPATTSLVNVVPKLNATGRDLLQNLLKCNPVQRISAEEALQHPYFSDFCPP 292
           MYPATTSLVNVVPKLNATGRDLLQNLLKCNPVQRISAEEALQHPYFSDFCPP
Sbjct: 241 MYPATTSLVNVVPKLNATGRDLLQNLLKCNPVQRISAEEALQHPYFSDFCPP 292


>gi|4557439 cyclin-dependent kinase 3 [Homo sapiens]
          Length = 305

 Score =  362 bits (928), Expect = e-100
 Identities = 179/289 (61%), Positives = 227/289 (78%), Gaps = 4/289 (1%)

Query: 1   MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKH 60
           M  ++K+EKIGEGTYG V+KAKNRET ++VALK++RLD + EGVPS+A+REI LLKELKH
Sbjct: 1   MDMFQKVEKIGEGTYGVVYKAKNRETGQLVALKKIRLDLEMEGVPSTAIREISLLKELKH 60

Query: 61  KNIVRLHDVLHSDKKLTLVFEFCDQDLKKYFDSCNG-DLDPEIVKSFLFQLLKGLGFCHS 119
            NIVRL DV+H+++KL LVFEF  QDLKKY DS  G +L   ++KS+LFQLL+G+ FCHS
Sbjct: 61  PNIVRLLDVVHNERKLYLVFEFLSQDLKKYMDSTPGSELPLHLIKSYLFQLLQGVSFCHS 120

Query: 120 RNVLHRDLKPQNLLINRNGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPDVLFGAKLY 179
             V+HRDLKPQNLLIN  G +KLADFGLARAFG+P+R Y+ EVVTLWYR P++L G+K Y
Sbjct: 121 HRVIHRDLKPQNLLINELGAIKLADFGLARAFGVPLRTYTHEVVTLWYRAPEILLGSKFY 180

Query: 180 STSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIFRLLGTPTEEQWPSMTKLPDYK-P 238
           +T++D+WS GCIFAE+    + LFPG+   DQL RIFR+LGTP+E+ WP +T+LPDYK  
Sbjct: 181 TTAVDIWSIGCIFAEMVTR-KALFPGDSEIDQLFRIFRMLGTPSEDTWPGVTQLPDYKGS 239

Query: 239 YPMYPATTSLVNVVPKLNATGRDLLQNLLKCNPVQRISAEEALQHPYFS 287
           +P +     L  +VP L   GRDLL  LL+ +P QRI+A+ AL HPYFS
Sbjct: 240 FPKW-TRKGLEEIVPNLEPEGRDLLMQLLQYDPSQRITAKTALAHPYFS 287


>gi|16936528 cyclin-dependent kinase 2 isoform 1 [Homo sapiens]
          Length = 298

 Score =  350 bits (898), Expect = 8e-97
 Identities = 176/294 (59%), Positives = 219/294 (74%), Gaps = 4/294 (1%)

Query: 1   MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKH 60
           M+ ++K+EKIGEGTYG V+KA+N+ T E+VALK++RLD + EGVPS+A+REI LLKEL H
Sbjct: 1   MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNH 60

Query: 61  KNIVRLHDVLHSDKKLTLVFEFCDQDLKKYFD-SCNGDLDPEIVKSFLFQLLKGLGFCHS 119
            NIV+L DV+H++ KL LVFEF  QDLKK+ D S    +   ++KS+LFQLL+GL FCHS
Sbjct: 61  PNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHS 120

Query: 120 RNVLHRDLKPQNLLINRNGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPDVLFGAKLY 179
             VLHRDLKPQNLLIN  G +KLADFGLARAFG+PVR Y+ EVVTLWYR P++L G K Y
Sbjct: 121 HRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYY 180

Query: 180 STSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIFRLLGTPTEEQWPSMTKLPDYKP- 238
           ST++D+WS GCIFAE+    R LFPG+   DQL RIFR LGTP E  WP +T +PDYKP 
Sbjct: 181 STAVDIWSLGCIFAEMVTR-RALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPS 239

Query: 239 YPMYPATTSLVNVVPKLNATGRDLLQNLLKCNPVQRISAEEALQHPYFSDFCPP 292
           +P + A      VVP L+  GR LL  +L  +P +RISA+ AL HP+F D   P
Sbjct: 240 FPKW-ARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKP 292


>gi|197333744 PCTAIRE protein kinase 1 isoform 2 [Homo sapiens]
          Length = 502

 Score =  339 bits (869), Expect = 2e-93
 Identities = 167/288 (57%), Positives = 216/288 (75%), Gaps = 5/288 (1%)

Query: 1   MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKH 60
           ++ Y KL+K+GEGTY TV+K K++ T  +VALK +RL+ + EG P +A+RE+ LLK+LKH
Sbjct: 168 LETYIKLDKLGEGTYATVYKGKSKLTDNLVALKEIRLEHE-EGAPCTAIREVSLLKDLKH 226

Query: 61  KNIVRLHDVLHSDKKLTLVFEFCDQDLKKYFDSCNGDLDPEIVKSFLFQLLKGLGFCHSR 120
            NIV LHD++H++K LTLVFE+ D+DLK+Y D C   ++   VK FLFQLL+GL +CH +
Sbjct: 227 ANIVTLHDIIHTEKSLTLVFEYLDKDLKQYLDDCGNIINMHNVKLFLFQLLRGLAYCHRQ 286

Query: 121 NVLHRDLKPQNLLINRNGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPDVLFGAKLYS 180
            VLHRDLKPQNLLIN  GELKLADFGLARA  IP + YS EVVTLWYRPPD+L G+  YS
Sbjct: 287 KVLHRDLKPQNLLINERGELKLADFGLARAKSIPTKTYSNEVVTLWYRPPDILLGSTDYS 346

Query: 181 TSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIFRLLGTPTEEQWPSMTKLPDYKP-- 238
           T IDMW  GCIF E+A  GRPLFPG+ V++QL  IFR+LGTPTEE WP +    ++K   
Sbjct: 347 TQIDMWGVGCIFYEMA-TGRPLFPGSTVEEQLHFIFRILGTPTEETWPGILSNEEFKTYN 405

Query: 239 YPMYPATTSLVNVVPKLNATGRDLLQNLLKCNPVQRISAEEALQHPYF 286
           YP Y A  +L++  P+L++ G DLL  LL+     RISAE+A++HP+F
Sbjct: 406 YPKYRA-EALLSHAPRLDSDGADLLTKLLQFEGRNRISAEDAMKHPFF 452


>gi|5453860 PCTAIRE protein kinase 1 isoform 1 [Homo sapiens]
          Length = 496

 Score =  339 bits (869), Expect = 2e-93
 Identities = 167/288 (57%), Positives = 216/288 (75%), Gaps = 5/288 (1%)

Query: 1   MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKH 60
           ++ Y KL+K+GEGTY TV+K K++ T  +VALK +RL+ + EG P +A+RE+ LLK+LKH
Sbjct: 162 LETYIKLDKLGEGTYATVYKGKSKLTDNLVALKEIRLEHE-EGAPCTAIREVSLLKDLKH 220

Query: 61  KNIVRLHDVLHSDKKLTLVFEFCDQDLKKYFDSCNGDLDPEIVKSFLFQLLKGLGFCHSR 120
            NIV LHD++H++K LTLVFE+ D+DLK+Y D C   ++   VK FLFQLL+GL +CH +
Sbjct: 221 ANIVTLHDIIHTEKSLTLVFEYLDKDLKQYLDDCGNIINMHNVKLFLFQLLRGLAYCHRQ 280

Query: 121 NVLHRDLKPQNLLINRNGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPDVLFGAKLYS 180
            VLHRDLKPQNLLIN  GELKLADFGLARA  IP + YS EVVTLWYRPPD+L G+  YS
Sbjct: 281 KVLHRDLKPQNLLINERGELKLADFGLARAKSIPTKTYSNEVVTLWYRPPDILLGSTDYS 340

Query: 181 TSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIFRLLGTPTEEQWPSMTKLPDYKP-- 238
           T IDMW  GCIF E+A  GRPLFPG+ V++QL  IFR+LGTPTEE WP +    ++K   
Sbjct: 341 TQIDMWGVGCIFYEMA-TGRPLFPGSTVEEQLHFIFRILGTPTEETWPGILSNEEFKTYN 399

Query: 239 YPMYPATTSLVNVVPKLNATGRDLLQNLLKCNPVQRISAEEALQHPYF 286
           YP Y A  +L++  P+L++ G DLL  LL+     RISAE+A++HP+F
Sbjct: 400 YPKYRA-EALLSHAPRLDSDGADLLTKLLQFEGRNRISAEDAMKHPFF 446


>gi|37595545 PCTAIRE protein kinase 2 [Homo sapiens]
          Length = 523

 Score =  338 bits (867), Expect = 3e-93
 Identities = 165/293 (56%), Positives = 215/293 (73%), Gaps = 5/293 (1%)

Query: 1   MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKH 60
           M+ Y KLEK+GEGTY TV+K +++ T  +VALK +RL+ + EG P +A+RE+ LLK+LKH
Sbjct: 189 METYIKLEKLGEGTYATVYKGRSKLTENLVALKEIRLEHE-EGAPCTAIREVSLLKDLKH 247

Query: 61  KNIVRLHDVLHSDKKLTLVFEFCDQDLKKYFDSCNGDLDPEIVKSFLFQLLKGLGFCHSR 120
            NIV LHD++H+DK LTLVFE+ D+DLK+Y D C   +    VK FL+Q+L+GL +CH R
Sbjct: 248 ANIVTLHDIVHTDKSLTLVFEYLDKDLKQYMDDCGNIMSMHNVKLFLYQILRGLAYCHRR 307

Query: 121 NVLHRDLKPQNLLINRNGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPDVLFGAKLYS 180
            VLHRDLKPQNLLIN  GELKLADFGLARA  +P + YS EVVTLWYRPPDVL G+  YS
Sbjct: 308 KVLHRDLKPQNLLINEKGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSSEYS 367

Query: 181 TSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIFRLLGTPTEEQWPSMTKLPDYKPY- 239
           T IDMW  GCIF E+A +GRPLFPG+ V+D+L  IFRLLGTP++E WP ++   ++K Y 
Sbjct: 368 TQIDMWGVGCIFFEMA-SGRPLFPGSTVEDELHLIFRLLGTPSQETWPGISSNEEFKNYN 426

Query: 240 -PMYPATTSLVNVVPKLNATGRDLLQNLLKCNPVQRISAEEALQHPYFSDFCP 291
            P Y     L+N  P+L++ G +L+   L+    +R+SAEEA++H YF    P
Sbjct: 427 FPKY-KPQPLINHAPRLDSEGIELITKFLQYESKKRVSAEEAMKHVYFRSLGP 478


>gi|47078233 PCTAIRE protein kinase 3 isoform a [Homo sapiens]
          Length = 504

 Score =  329 bits (843), Expect = 2e-90
 Identities = 164/288 (56%), Positives = 205/288 (71%), Gaps = 5/288 (1%)

Query: 1   MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKH 60
           ++ Y KL+K+GEGTY TVFK +++ T  +VALK +RL+ + EG P +A+RE+ LLK LKH
Sbjct: 171 LETYVKLDKLGEGTYATVFKGRSKLTENLVALKEIRLEHE-EGAPCTAIREVSLLKNLKH 229

Query: 61  KNIVRLHDVLHSDKKLTLVFEFCDQDLKKYFDSCNGDLDPEIVKSFLFQLLKGLGFCHSR 120
            NIV LHD++H+D+ LTLVFE+ D DLK+Y D C   +    VK F+FQLL+GL +CH R
Sbjct: 230 ANIVTLHDLIHTDRSLTLVFEYLDSDLKQYLDHCGNLMSMHNVKIFMFQLLRGLAYCHHR 289

Query: 121 NVLHRDLKPQNLLINRNGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPDVLFGAKLYS 180
            +LHRDLKPQNLLIN  GELKLADFGLARA  +P + YS EVVTLWYRPPDVL G+  YS
Sbjct: 290 KILHRDLKPQNLLINERGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTEYS 349

Query: 181 TSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIFRLLGTPTEEQWPSMTKLPDYKPY- 239
           T IDMW  GCI  E+A  GRPLFPG+ V ++L  IFRLLGTPTEE WP +T   +++ Y 
Sbjct: 350 TPIDMWGVGCIHYEMA-TGRPLFPGSTVKEELHLIFRLLGTPTEETWPGVTAFSEFRTYS 408

Query: 240 -PMYPATTSLVNVVPKLNATGRDLLQNLLKCNPVQRISAEEALQHPYF 286
            P Y     L+N  P+L+  G  LL +LL      R+SAE AL H YF
Sbjct: 409 FPCY-LPQPLINHAPRLDTDGIHLLSSLLLYESKSRMSAEAALSHSYF 455


>gi|47078231 PCTAIRE protein kinase 3 isoform b [Homo sapiens]
          Length = 474

 Score =  329 bits (843), Expect = 2e-90
 Identities = 164/288 (56%), Positives = 205/288 (71%), Gaps = 5/288 (1%)

Query: 1   MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKH 60
           ++ Y KL+K+GEGTY TVFK +++ T  +VALK +RL+ + EG P +A+RE+ LLK LKH
Sbjct: 141 LETYVKLDKLGEGTYATVFKGRSKLTENLVALKEIRLEHE-EGAPCTAIREVSLLKNLKH 199

Query: 61  KNIVRLHDVLHSDKKLTLVFEFCDQDLKKYFDSCNGDLDPEIVKSFLFQLLKGLGFCHSR 120
            NIV LHD++H+D+ LTLVFE+ D DLK+Y D C   +    VK F+FQLL+GL +CH R
Sbjct: 200 ANIVTLHDLIHTDRSLTLVFEYLDSDLKQYLDHCGNLMSMHNVKIFMFQLLRGLAYCHHR 259

Query: 121 NVLHRDLKPQNLLINRNGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPDVLFGAKLYS 180
            +LHRDLKPQNLLIN  GELKLADFGLARA  +P + YS EVVTLWYRPPDVL G+  YS
Sbjct: 260 KILHRDLKPQNLLINERGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTEYS 319

Query: 181 TSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIFRLLGTPTEEQWPSMTKLPDYKPY- 239
           T IDMW  GCI  E+A  GRPLFPG+ V ++L  IFRLLGTPTEE WP +T   +++ Y 
Sbjct: 320 TPIDMWGVGCIHYEMA-TGRPLFPGSTVKEELHLIFRLLGTPTEETWPGVTAFSEFRTYS 378

Query: 240 -PMYPATTSLVNVVPKLNATGRDLLQNLLKCNPVQRISAEEALQHPYF 286
            P Y     L+N  P+L+  G  LL +LL      R+SAE AL H YF
Sbjct: 379 FPCY-LPQPLINHAPRLDTDGIHLLSSLLLYESKSRMSAEAALSHSYF 425


>gi|47078229 PCTAIRE protein kinase 3 isoform b [Homo sapiens]
          Length = 474

 Score =  329 bits (843), Expect = 2e-90
 Identities = 164/288 (56%), Positives = 205/288 (71%), Gaps = 5/288 (1%)

Query: 1   MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKH 60
           ++ Y KL+K+GEGTY TVFK +++ T  +VALK +RL+ + EG P +A+RE+ LLK LKH
Sbjct: 141 LETYVKLDKLGEGTYATVFKGRSKLTENLVALKEIRLEHE-EGAPCTAIREVSLLKNLKH 199

Query: 61  KNIVRLHDVLHSDKKLTLVFEFCDQDLKKYFDSCNGDLDPEIVKSFLFQLLKGLGFCHSR 120
            NIV LHD++H+D+ LTLVFE+ D DLK+Y D C   +    VK F+FQLL+GL +CH R
Sbjct: 200 ANIVTLHDLIHTDRSLTLVFEYLDSDLKQYLDHCGNLMSMHNVKIFMFQLLRGLAYCHHR 259

Query: 121 NVLHRDLKPQNLLINRNGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPDVLFGAKLYS 180
            +LHRDLKPQNLLIN  GELKLADFGLARA  +P + YS EVVTLWYRPPDVL G+  YS
Sbjct: 260 KILHRDLKPQNLLINERGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTEYS 319

Query: 181 TSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIFRLLGTPTEEQWPSMTKLPDYKPY- 239
           T IDMW  GCI  E+A  GRPLFPG+ V ++L  IFRLLGTPTEE WP +T   +++ Y 
Sbjct: 320 TPIDMWGVGCIHYEMA-TGRPLFPGSTVKEELHLIFRLLGTPTEETWPGVTAFSEFRTYS 378

Query: 240 -PMYPATTSLVNVVPKLNATGRDLLQNLLKCNPVQRISAEEALQHPYF 286
            P Y     L+N  P+L+  G  LL +LL      R+SAE AL H YF
Sbjct: 379 FPCY-LPQPLINHAPRLDTDGIHLLSSLLLYESKSRMSAEAALSHSYF 425


>gi|4502709 cell division cycle 2 isoform 1 [Homo sapiens]
          Length = 297

 Score =  326 bits (836), Expect = 1e-89
 Identities = 166/291 (57%), Positives = 212/291 (72%), Gaps = 5/291 (1%)

Query: 1   MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKH 60
           M+ Y K+EKIGEGTYG V+K +++ T ++VA+K++RL+ ++EGVPS+A+REI LLKEL+H
Sbjct: 1   MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRH 60

Query: 61  KNIVRLHDVLHSDKKLTLVFEFCDQDLKKYFDSCNGD--LDPEIVKSFLFQLLKGLGFCH 118
            NIV L DVL  D +L L+FEF   DLKKY DS      +D  +VKS+L+Q+L+G+ FCH
Sbjct: 61  PNIVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFCH 120

Query: 119 SRNVLHRDLKPQNLLINRNGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPDVLFGAKL 178
           SR VLHRDLKPQNLLI+  G +KLADFGLARAFGIP+R Y+ EVVTLWYR P+VL G+  
Sbjct: 121 SRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEVVTLWYRSPEVLLGSAR 180

Query: 179 YSTSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIFRLLGTPTEEQWPSMTKLPDYK- 237
           YST +D+WS G IFAELA   +PLF G+   DQL RIFR LGTP  E WP +  L DYK 
Sbjct: 181 YSTPVDIWSIGTIFAELATK-KPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKN 239

Query: 238 PYPMYPATTSLVNVVPKLNATGRDLLQNLLKCNPVQRISAEEALQHPYFSD 288
            +P +    SL + V  L+  G DLL  +L  +P +RIS + AL HPYF+D
Sbjct: 240 TFPKW-KPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFND 289


>gi|195927041 cell division cycle 2 isoform 3 [Homo sapiens]
          Length = 297

 Score =  324 bits (831), Expect = 5e-89
 Identities = 164/291 (56%), Positives = 211/291 (72%), Gaps = 5/291 (1%)

Query: 1   MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKH 60
           M+ Y K+EKIGEGTYG V+K +++ T ++VA+K++RL+ ++EGVPS+A+REI LLKEL+H
Sbjct: 1   MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRH 60

Query: 61  KNIVRLHDVLHSDKKLTLVFEFCDQDLKKYFDSCNGD--LDPEIVKSFLFQLLKGLGFCH 118
            NIV L DVL  D +L L+FEF   DLKKY DS      +D  +VKS+L+Q+L+G+ FCH
Sbjct: 61  PNIVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFCH 120

Query: 119 SRNVLHRDLKPQNLLINRNGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPDVLFGAKL 178
           SR VLHRDLKPQNLLI+  G +KLADFGLARAFGIP+R Y+ E +TLWYR P+VL G+  
Sbjct: 121 SRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEAITLWYRSPEVLLGSAR 180

Query: 179 YSTSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIFRLLGTPTEEQWPSMTKLPDYK- 237
           YST +D+WS G IFAELA   +PLF G+   DQL RIFR LGTP  E WP +  L DYK 
Sbjct: 181 YSTPVDIWSIGTIFAELATK-KPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKN 239

Query: 238 PYPMYPATTSLVNVVPKLNATGRDLLQNLLKCNPVQRISAEEALQHPYFSD 288
            +P +    SL + V  L+  G DLL  +L  +P +RIS + AL HPYF+D
Sbjct: 240 TFPKW-KPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFND 289


>gi|6912584 PFTAIRE protein kinase 1 [Homo sapiens]
          Length = 451

 Score =  305 bits (781), Expect = 3e-83
 Identities = 160/293 (54%), Positives = 203/293 (69%), Gaps = 8/293 (2%)

Query: 4   YEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKHKNI 63
           YEKLEK+GEG+Y TV+K K++   ++VALK +RL ++ EG P +A+RE  LLK LKH NI
Sbjct: 117 YEKLEKLGEGSYATVYKGKSKVNGKLVALKVIRLQEE-EGTPFTAIREASLLKGLKHANI 175

Query: 64  VRLHDVLHSDKKLTLVFEFCDQDLKKYFDSCNGDLDPEIVKSFLFQLLKGLGFCHSRNVL 123
           V LHD++H+ + LTLVFE+   DL +Y D   G L P+ VK FLFQLL+GL + H R +L
Sbjct: 176 VLLHDIIHTKETLTLVFEYVHTDLCQYMDKHPGGLHPDNVKLFLFQLLRGLSYIHQRYIL 235

Query: 124 HRDLKPQNLLINRNGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPDVLFGAKLYSTSI 183
           HRDLKPQNLLI+  GELKLADFGLARA  +P   YS EVVTLWYRPPDVL G+  YST +
Sbjct: 236 HRDLKPQNLLISDTGELKLADFGLARAKSVPSHTYSNEVVTLWYRPPDVLLGSTEYSTCL 295

Query: 184 DMWSAGCIFAELANAGRPLFPG-NDVDDQLKRIFRLLGTPTEEQWPSMTKLPDYKP--YP 240
           DMW  GCIF E+   G   FPG  D+ DQL+RIF +LGTP E+ WP +  LP +KP  + 
Sbjct: 296 DMWGVGCIFVEMIQ-GVAAFPGMKDIQDQLERIFLVLGTPNEDTWPGVHSLPHFKPERFT 354

Query: 241 MYPATTSLVNVVPKLNAT--GRDLLQNLLKCNPVQRISAEEALQHPYFSDFCP 291
           +Y ++ +L     KL+      DL   LL+C+P  R+SA+ AL H YFSD  P
Sbjct: 355 LY-SSKNLRQAWNKLSYVNHAEDLASKLLQCSPKNRLSAQAALSHEYFSDLPP 406


>gi|21040235 PFTAIRE protein kinase 2 [Homo sapiens]
          Length = 384

 Score =  286 bits (732), Expect = 1e-77
 Identities = 152/289 (52%), Positives = 202/289 (69%), Gaps = 8/289 (2%)

Query: 4   YEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKHKNI 63
           Y  LEK+GEG+Y TV+K  +R   ++VALK + ++ + EGVP +A+RE  LLK LKH NI
Sbjct: 52  YLNLEKLGEGSYATVYKGISRINGQLVALKVISMNAE-EGVPFTAIREASLLKGLKHANI 110

Query: 64  VRLHDVLHSDKKLTLVFEFCDQDLKKYFDSCNGDLDPEIVKSFLFQLLKGLGFCHSRNVL 123
           V LHD++H+ + LT VFE+   DL +Y     G L P  V+ F+FQLL+GL + H ++VL
Sbjct: 111 VLLHDIIHTKETLTFVFEYMHTDLAQYMSQHPGGLHPHNVRLFMFQLLRGLAYIHHQHVL 170

Query: 124 HRDLKPQNLLINRNGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPDVLFGAKLYSTSI 183
           HRDLKPQNLLI+  GELKLADFGLARA  IP + YS+EVVTLWYRPPD L GA  YS+ +
Sbjct: 171 HRDLKPQNLLISHLGELKLADFGLARAKSIPSQTYSSEVVTLWYRPPDALLGATEYSSEL 230

Query: 184 DMWSAGCIFAELANAGRPLFPG-NDVDDQLKRIFRLLGTPTEEQWPSMTKLPDYKP--YP 240
           D+W AGCIF E+   G+PLFPG +++ +QL++I+ +LG PTE+ WP ++KLP+Y P  +P
Sbjct: 231 DIWGAGCIFIEMFQ-GQPLFPGVSNILEQLEKIWEVLGVPTEDTWPGVSKLPNYNPEWFP 289

Query: 241 MYPATTSLVNVVPKLNAT--GRDLLQNLLKCNPVQRISAEEALQHPYFS 287
           + P   SL  V  +L       DL   +LK  P  R+SA+EAL H YFS
Sbjct: 290 L-PTPRSLHVVWNRLGRVPEAEDLASQMLKGFPRDRVSAQEALVHDYFS 337


>gi|166362719 cyclin-dependent kinase 2 isoform 2 [Homo sapiens]
          Length = 264

 Score =  284 bits (726), Expect = 7e-77
 Identities = 154/294 (52%), Positives = 191/294 (64%), Gaps = 38/294 (12%)

Query: 1   MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKH 60
           M+ ++K+EKIGEGTYG V+KA+N+ T E+VALK++RLD + EGVPS+A+REI LLKEL H
Sbjct: 1   MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNH 60

Query: 61  KNIVRLHDVLHSDKKLTLVFEFCDQDLKKYFD-SCNGDLDPEIVKSFLFQLLKGLGFCHS 119
            NIV+L DV+H++ KL LVFEF  QDLKK+ D S    +   ++KS+LFQLL+GL FCHS
Sbjct: 61  PNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHS 120

Query: 120 RNVLHRDLKPQNLLINRNGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPDVLFGAKLY 179
             VLHRDLKPQNLLIN  G +KLADFGLARAFG+PVR Y+ EV                 
Sbjct: 121 HRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVTR--------------- 165

Query: 180 STSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIFRLLGTPTEEQWPSMTKLPDYKP- 238
                               R LFPG+   DQL RIFR LGTP E  WP +T +PDYKP 
Sbjct: 166 --------------------RALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPS 205

Query: 239 YPMYPATTSLVNVVPKLNATGRDLLQNLLKCNPVQRISAEEALQHPYFSDFCPP 292
           +P + A      VVP L+  GR LL  +L  +P +RISA+ AL HP+F D   P
Sbjct: 206 FPKW-ARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKP 258


>gi|4502743 cyclin-dependent kinase 7 [Homo sapiens]
          Length = 346

 Score =  258 bits (660), Expect = 3e-69
 Identities = 133/290 (45%), Positives = 187/290 (64%), Gaps = 5/290 (1%)

Query: 2   QKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDE---GVPSSALREICLLKEL 58
           ++YEKL+ +GEG + TV+KA+++ T++IVA+K+++L    E   G+  +ALREI LL+EL
Sbjct: 10  KRYEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQEL 69

Query: 59  KHKNIVRLHDVLHSDKKLTLVFEFCDQDLKKYFDSCNGDLDPEIVKSFLFQLLKGLGFCH 118
            H NI+ L D       ++LVF+F + DL+      +  L P  +K+++   L+GL + H
Sbjct: 70  SHPNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSHIKAYMLMTLQGLEYLH 129

Query: 119 SRNVLHRDLKPQNLLINRNGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPDVLFGAKL 178
              +LHRDLKP NLL++ NG LKLADFGLA++FG P R Y+ +VVT WYR P++LFGA++
Sbjct: 130 QHWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARM 189

Query: 179 YSTSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIFRLLGTPTEEQWPSMTKLPDYKP 238
           Y   +DMW+ GCI AEL     P  PG+   DQL RIF  LGTPTEEQWP M  LPDY  
Sbjct: 190 YGVGVDMWAVGCILAELL-LRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYVT 248

Query: 239 YPMYPATTSLVNVVPKLNATGRDLLQNLLKCNPVQRISAEEALQHPYFSD 288
           +  +P    L ++         DL+Q L   NP  RI+A +AL+  YFS+
Sbjct: 249 FKSFPG-IPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSN 297


>gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens]
          Length = 770

 Score =  240 bits (612), Expect = 1e-63
 Identities = 122/292 (41%), Positives = 186/292 (63%), Gaps = 5/292 (1%)

Query: 1   MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKH 60
           +++++ L +I EGTYG V++AK+++T EIVALKR++++ + EG P ++LREI  + + +H
Sbjct: 410 VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQH 469

Query: 61  KNIVRLHDVLHSDK--KLTLVFEFCDQDLKKYFDSCNGDLDPEIVKSFLFQLLKGLGFCH 118
            NIV + +++      K+ +V  + + DLK   ++      P  VK+ + QLL+G+   H
Sbjct: 470 PNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLH 529

Query: 119 SRNVLHRDLKPQNLLINRNGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPDVLFGAKL 178
              +LHRDLK  NLL++  G LK+ DFGLAR +G P++ Y+  VVT WYR P++L GAK 
Sbjct: 530 DNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKE 589

Query: 179 YSTSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIFRLLGTPTEEQWPSMTKLPDYK- 237
           YST++DMWS GCIF EL    +PLFPGN   DQ+ ++F+ LGTP+E+ WP  ++LP  K 
Sbjct: 590 YSTAVDMWSVGCIFGELLTQ-KPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKK 648

Query: 238 -PYPMYPATTSLVNVVPKLNATGRDLLQNLLKCNPVQRISAEEALQHPYFSD 288
             +  +P           L+  G DL+   L   P +RISAE+ L+H YF +
Sbjct: 649 MTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRE 700


>gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens]
          Length = 780

 Score =  240 bits (612), Expect = 1e-63
 Identities = 122/292 (41%), Positives = 186/292 (63%), Gaps = 5/292 (1%)

Query: 1   MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKH 60
           +++++ L +I EGTYG V++AK+++T EIVALKR++++ + EG P ++LREI  + + +H
Sbjct: 420 VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQH 479

Query: 61  KNIVRLHDVLHSDK--KLTLVFEFCDQDLKKYFDSCNGDLDPEIVKSFLFQLLKGLGFCH 118
            NIV + +++      K+ +V  + + DLK   ++      P  VK+ + QLL+G+   H
Sbjct: 480 PNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLH 539

Query: 119 SRNVLHRDLKPQNLLINRNGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPDVLFGAKL 178
              +LHRDLK  NLL++  G LK+ DFGLAR +G P++ Y+  VVT WYR P++L GAK 
Sbjct: 540 DNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAKE 599

Query: 179 YSTSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIFRLLGTPTEEQWPSMTKLPDYK- 237
           YST++DMWS GCIF EL    +PLFPGN   DQ+ ++F+ LGTP+E+ WP  ++LP  K 
Sbjct: 600 YSTAVDMWSVGCIFGELLTQ-KPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKK 658

Query: 238 -PYPMYPATTSLVNVVPKLNATGRDLLQNLLKCNPVQRISAEEALQHPYFSD 288
             +  +P           L+  G DL+   L   P +RISAE+ L+H YF +
Sbjct: 659 MTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRE 710


>gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isoform
           9 [Homo sapiens]
          Length = 771

 Score =  240 bits (612), Expect = 1e-63
 Identities = 122/292 (41%), Positives = 186/292 (63%), Gaps = 5/292 (1%)

Query: 1   MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKH 60
           +++++ L +I EGTYG V++AK+++T EIVALKR++++ + EG P ++LREI  + + +H
Sbjct: 411 VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQH 470

Query: 61  KNIVRLHDVLHSDK--KLTLVFEFCDQDLKKYFDSCNGDLDPEIVKSFLFQLLKGLGFCH 118
            NIV + +++      K+ +V  + + DLK   ++      P  VK+ + QLL+G+   H
Sbjct: 471 PNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLH 530

Query: 119 SRNVLHRDLKPQNLLINRNGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPDVLFGAKL 178
              +LHRDLK  NLL++  G LK+ DFGLAR +G P++ Y+  VVTLWYR P++L GAK 
Sbjct: 531 DNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAKE 590

Query: 179 YSTSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIFRLLGTPTEEQWPSMTKLPDYK- 237
           YST++DMWS GCIF EL    +PLFPG    DQ+ ++F+ LGTP+E+ WP  ++LP  K 
Sbjct: 591 YSTAVDMWSVGCIFGELLTQ-KPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKK 649

Query: 238 -PYPMYPATTSLVNVVPKLNATGRDLLQNLLKCNPVQRISAEEALQHPYFSD 288
             +  +P           L+  G DL+   L   P +RISAE+ L+H YF +
Sbjct: 650 MTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRE 701


>gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isoform
           8 [Homo sapiens]
          Length = 780

 Score =  240 bits (612), Expect = 1e-63
 Identities = 122/292 (41%), Positives = 186/292 (63%), Gaps = 5/292 (1%)

Query: 1   MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKH 60
           +++++ L +I EGTYG V++AK+++T EIVALKR++++ + EG P ++LREI  + + +H
Sbjct: 420 VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQH 479

Query: 61  KNIVRLHDVLHSDK--KLTLVFEFCDQDLKKYFDSCNGDLDPEIVKSFLFQLLKGLGFCH 118
            NIV + +++      K+ +V  + + DLK   ++      P  VK+ + QLL+G+   H
Sbjct: 480 PNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLH 539

Query: 119 SRNVLHRDLKPQNLLINRNGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPDVLFGAKL 178
              +LHRDLK  NLL++  G LK+ DFGLAR +G P++ Y+  VVTLWYR P++L GAK 
Sbjct: 540 DNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAKE 599

Query: 179 YSTSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIFRLLGTPTEEQWPSMTKLPDYK- 237
           YST++DMWS GCIF EL    +PLFPG    DQ+ ++F+ LGTP+E+ WP  ++LP  K 
Sbjct: 600 YSTAVDMWSVGCIFGELLTQ-KPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKK 658

Query: 238 -PYPMYPATTSLVNVVPKLNATGRDLLQNLLKCNPVQRISAEEALQHPYFSD 288
             +  +P           L+  G DL+   L   P +RISAE+ L+H YF +
Sbjct: 659 MTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRE 710


>gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isoform
           5 [Homo sapiens]
          Length = 748

 Score =  240 bits (612), Expect = 1e-63
 Identities = 122/292 (41%), Positives = 186/292 (63%), Gaps = 5/292 (1%)

Query: 1   MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKH 60
           +++++ L +I EGTYG V++AK+++T EIVALKR++++ + EG P ++LREI  + + +H
Sbjct: 388 VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQH 447

Query: 61  KNIVRLHDVLHSDK--KLTLVFEFCDQDLKKYFDSCNGDLDPEIVKSFLFQLLKGLGFCH 118
            NIV + +++      K+ +V  + + DLK   ++      P  VK+ + QLL+G+   H
Sbjct: 448 PNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLH 507

Query: 119 SRNVLHRDLKPQNLLINRNGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPDVLFGAKL 178
              +LHRDLK  NLL++  G LK+ DFGLAR +G P++ Y+  VVTLWYR P++L GAK 
Sbjct: 508 DNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAKE 567

Query: 179 YSTSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIFRLLGTPTEEQWPSMTKLPDYK- 237
           YST++DMWS GCIF EL    +PLFPG    DQ+ ++F+ LGTP+E+ WP  ++LP  K 
Sbjct: 568 YSTAVDMWSVGCIFGELLTQ-KPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKK 626

Query: 238 -PYPMYPATTSLVNVVPKLNATGRDLLQNLLKCNPVQRISAEEALQHPYFSD 288
             +  +P           L+  G DL+   L   P +RISAE+ L+H YF +
Sbjct: 627 MTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRE 678


>gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isoform
           4 [Homo sapiens]
          Length = 737

 Score =  240 bits (612), Expect = 1e-63
 Identities = 122/292 (41%), Positives = 186/292 (63%), Gaps = 5/292 (1%)

Query: 1   MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKH 60
           +++++ L +I EGTYG V++AK+++T EIVALKR++++ + EG P ++LREI  + + +H
Sbjct: 377 VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQH 436

Query: 61  KNIVRLHDVLHSDK--KLTLVFEFCDQDLKKYFDSCNGDLDPEIVKSFLFQLLKGLGFCH 118
            NIV + +++      K+ +V  + + DLK   ++      P  VK+ + QLL+G+   H
Sbjct: 437 PNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLH 496

Query: 119 SRNVLHRDLKPQNLLINRNGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPDVLFGAKL 178
              +LHRDLK  NLL++  G LK+ DFGLAR +G P++ Y+  VVTLWYR P++L GAK 
Sbjct: 497 DNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAKE 556

Query: 179 YSTSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIFRLLGTPTEEQWPSMTKLPDYK- 237
           YST++DMWS GCIF EL    +PLFPG    DQ+ ++F+ LGTP+E+ WP  ++LP  K 
Sbjct: 557 YSTAVDMWSVGCIFGELLTQ-KPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKK 615

Query: 238 -PYPMYPATTSLVNVVPKLNATGRDLLQNLLKCNPVQRISAEEALQHPYFSD 288
             +  +P           L+  G DL+   L   P +RISAE+ L+H YF +
Sbjct: 616 MTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRE 667


>gi|16332360 cell division cycle 2-like 1 (PITSLRE proteins) isoform
           3 [Homo sapiens]
          Length = 526

 Score =  240 bits (612), Expect = 1e-63
 Identities = 122/292 (41%), Positives = 186/292 (63%), Gaps = 5/292 (1%)

Query: 1   MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKH 60
           +++++ L +I EGTYG V++AK+++T EIVALKR++++ + EG P ++LREI  + + +H
Sbjct: 166 VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQH 225

Query: 61  KNIVRLHDVLHSDK--KLTLVFEFCDQDLKKYFDSCNGDLDPEIVKSFLFQLLKGLGFCH 118
            NIV + +++      K+ +V  + + DLK   ++      P  VK+ + QLL+G+   H
Sbjct: 226 PNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLH 285

Query: 119 SRNVLHRDLKPQNLLINRNGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPDVLFGAKL 178
              +LHRDLK  NLL++  G LK+ DFGLAR +G P++ Y+  VVTLWYR P++L GAK 
Sbjct: 286 DNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAKE 345

Query: 179 YSTSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIFRLLGTPTEEQWPSMTKLPDYK- 237
           YST++DMWS GCIF EL    +PLFPG    DQ+ ++F+ LGTP+E+ WP  ++LP  K 
Sbjct: 346 YSTAVDMWSVGCIFGELLTQ-KPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKK 404

Query: 238 -PYPMYPATTSLVNVVPKLNATGRDLLQNLLKCNPVQRISAEEALQHPYFSD 288
             +  +P           L+  G DL+   L   P +RISAE+ L+H YF +
Sbjct: 405 MTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRE 456


>gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isoform
           2 [Homo sapiens]
          Length = 782

 Score =  240 bits (612), Expect = 1e-63
 Identities = 122/292 (41%), Positives = 186/292 (63%), Gaps = 5/292 (1%)

Query: 1   MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKH 60
           +++++ L +I EGTYG V++AK+++T EIVALKR++++ + EG P ++LREI  + + +H
Sbjct: 422 VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQH 481

Query: 61  KNIVRLHDVLHSDK--KLTLVFEFCDQDLKKYFDSCNGDLDPEIVKSFLFQLLKGLGFCH 118
            NIV + +++      K+ +V  + + DLK   ++      P  VK+ + QLL+G+   H
Sbjct: 482 PNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGEVKTLMIQLLRGVKHLH 541

Query: 119 SRNVLHRDLKPQNLLINRNGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPDVLFGAKL 178
              +LHRDLK  NLL++  G LK+ DFGLAR +G P++ Y+  VVTLWYR P++L GAK 
Sbjct: 542 DNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAKE 601

Query: 179 YSTSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIFRLLGTPTEEQWPSMTKLPDYK- 237
           YST++DMWS GCIF EL    +PLFPG    DQ+ ++F+ LGTP+E+ WP  ++LP  K 
Sbjct: 602 YSTAVDMWSVGCIFGELLTQ-KPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKK 660

Query: 238 -PYPMYPATTSLVNVVPKLNATGRDLLQNLLKCNPVQRISAEEALQHPYFSD 288
             +  +P           L+  G DL+   L   P +RISAE+ L+H YF +
Sbjct: 661 MTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYFRE 712


>gi|223718134 cyclin-dependent kinase 6 [Homo sapiens]
          Length = 326

 Score =  239 bits (609), Expect = 3e-63
 Identities = 136/297 (45%), Positives = 182/297 (61%), Gaps = 15/297 (5%)

Query: 2   QKYEKLEKIGEGTYGTVFKAKN-RETHEIVALKRVRLDDDDEGVPSSALREICLLKELK- 59
           Q+YE + +IGEG YG VFKA++ +     VALKRVR+   +EG+P S +RE+ +L+ L+ 
Sbjct: 11  QQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEGMPLSTIREVAVLRHLET 70

Query: 60  --HKNIVRLHDVL-----HSDKKLTLVFEFCDQDLKKYFDSC-NGDLDPEIVKSFLFQLL 111
             H N+VRL DV        + KLTLVFE  DQDL  Y D      +  E +K  +FQLL
Sbjct: 71  FEHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPEPGVPTETIKDMMFQLL 130

Query: 112 KGLGFCHSRNVLHRDLKPQNLLINRNGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPD 171
           +GL F HS  V+HRDLKPQN+L+  +G++KLADFGLAR +   +   S  VVTLWYR P+
Sbjct: 131 RGLDFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLARIYSFQMALTSV-VVTLWYRAPE 189

Query: 172 VLFGAKLYSTSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIFRLLGTPTEEQWPSMT 231
           VL  +  Y+T +D+WS GCIFAE+    +PLF G+   DQL +I  ++G P EE WP   
Sbjct: 190 VLLQSS-YATPVDLWSVGCIFAEMFRR-KPLFRGSSDVDQLGKILDVIGLPGEEDWPRDV 247

Query: 232 KLPDYKPYPMYPATTSLVNVVPKLNATGRDLLQNLLKCNPVQRISAEEALQHPYFSD 288
            LP    +    +   +   V  ++  G+DLL   L  NP +RISA  AL HPYF D
Sbjct: 248 ALPRQAFHS--KSAQPIEKFVTDIDELGKDLLLKCLTFNPAKRISAYSALSHPYFQD 302


>gi|4502741 cyclin-dependent kinase 6 [Homo sapiens]
          Length = 326

 Score =  239 bits (609), Expect = 3e-63
 Identities = 136/297 (45%), Positives = 182/297 (61%), Gaps = 15/297 (5%)

Query: 2   QKYEKLEKIGEGTYGTVFKAKN-RETHEIVALKRVRLDDDDEGVPSSALREICLLKELK- 59
           Q+YE + +IGEG YG VFKA++ +     VALKRVR+   +EG+P S +RE+ +L+ L+ 
Sbjct: 11  QQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEGMPLSTIREVAVLRHLET 70

Query: 60  --HKNIVRLHDVL-----HSDKKLTLVFEFCDQDLKKYFDSC-NGDLDPEIVKSFLFQLL 111
             H N+VRL DV        + KLTLVFE  DQDL  Y D      +  E +K  +FQLL
Sbjct: 71  FEHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPEPGVPTETIKDMMFQLL 130

Query: 112 KGLGFCHSRNVLHRDLKPQNLLINRNGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPD 171
           +GL F HS  V+HRDLKPQN+L+  +G++KLADFGLAR +   +   S  VVTLWYR P+
Sbjct: 131 RGLDFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLARIYSFQMALTSV-VVTLWYRAPE 189

Query: 172 VLFGAKLYSTSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIFRLLGTPTEEQWPSMT 231
           VL  +  Y+T +D+WS GCIFAE+    +PLF G+   DQL +I  ++G P EE WP   
Sbjct: 190 VLLQSS-YATPVDLWSVGCIFAEMFRR-KPLFRGSSDVDQLGKILDVIGLPGEEDWPRDV 247

Query: 232 KLPDYKPYPMYPATTSLVNVVPKLNATGRDLLQNLLKCNPVQRISAEEALQHPYFSD 288
            LP    +    +   +   V  ++  G+DLL   L  NP +RISA  AL HPYF D
Sbjct: 248 ALPRQAFHS--KSAQPIEKFVTDIDELGKDLLLKCLTFNPAKRISAYSALSHPYFQD 302


>gi|148596926 cyclin-dependent kinase 10 isoform a [Homo sapiens]
          Length = 360

 Score =  239 bits (609), Expect = 3e-63
 Identities = 127/291 (43%), Positives = 184/291 (63%), Gaps = 4/291 (1%)

Query: 1   MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKH 60
           ++++EKL +IGEGTYG V++A++ +T EIVALK+VR+D + +G+P S+LREI LL  L+H
Sbjct: 36  VKEFEKLNRIGEGTYGIVYRARDTQTDEIVALKKVRMDKEKDGIPISSLREITLLLRLRH 95

Query: 61  KNIVRLHDVLHSD--KKLTLVFEFCDQDLKKYFDSCNGDLDPEIVKSFLFQLLKGLGFCH 118
            NIV L +V+  +  + + LV  +C+QDL    ++         VK  + Q+L+GL + H
Sbjct: 96  PNIVELKEVVVGNHLESIFLVMGYCEQDLASLLENMPTPFSEAQVKCIVLQVLRGLQYLH 155

Query: 119 SRNVLHRDLKPQNLLINRNGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPDVLFGAKL 178
              ++HRDLK  NLL+   G +K ADFGLARA+G+PV+  + +VVTLWYR P++L G   
Sbjct: 156 RNFIIHRDLKVSNLLMTDKGCVKTADFGLARAYGVPVKPMTPKVVTLWYRAPELLLGTTT 215

Query: 179 YSTSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIFRLLGTPTEEQWPSMTKLPDYKP 238
            +TSIDMW+ GCI AEL  A RPL PG     Q+  I +LLGTP+E  WP  +KLP    
Sbjct: 216 QTTSIDMWAVGCILAELL-AHRPLLPGTSEIHQIDLIVQLLGTPSENIWPGFSKLPLVGQ 274

Query: 239 YPMYPAT-TSLVNVVPKLNATGRDLLQNLLKCNPVQRISAEEALQHPYFSD 288
           Y +      +L +  P L+  G  LL  L   +P +R +A + L+  YF +
Sbjct: 275 YSLRKQPYNNLKHKFPWLSEAGLRLLHFLFMYDPKKRATAGDCLESSYFKE 325


>gi|89903018 cell cycle related kinase isoform 3 [Homo sapiens]
          Length = 346

 Score =  237 bits (605), Expect = 8e-63
 Identities = 133/289 (46%), Positives = 178/289 (61%), Gaps = 4/289 (1%)

Query: 1   MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELK- 59
           M +Y  L +IGEG +G VFKAK+ ET EIVALK+V L   ++G P+ ALREI  L+E++ 
Sbjct: 1   MDQYCILGRIGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGFPNQALREIKALQEMED 60

Query: 60  HKNIVRLHDVLHSDKKLTLVFEFCDQDLKKYFDSCNGDLDPEIVKSFLFQLLKGLGFCHS 119
           ++ +V+L  V        L FEF   DL +        L    VKS+L  LLKG+ FCH+
Sbjct: 61  NQYVVQLKAVFPHGGGFVLAFEFMLSDLAEVVRHAQRPLAQAQVKSYLQMLLKGVAFCHA 120

Query: 120 RNVLHRDLKPQNLLINRNGELKLADFGLARAFGIP-VRCYSAEVVTLWYRPPDVLFGAKL 178
            N++HRDLKP NLLI+ +G+LK+ADFGLAR F     R Y+ +V T WYR P++L+GA+ 
Sbjct: 121 NNIVHRDLKPANLLISASGQLKIADFGLARVFSPDGSRLYTHQVATRWYRAPELLYGARQ 180

Query: 179 YSTSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIFRLLGTPTEEQWPSMTKLPDYKP 238
           Y   +D+WS GCI  EL N G PLFPG +  +QL  + R+LGTP  + WP +T+LPDY  
Sbjct: 181 YDQGVDLWSVGCIMGELLN-GSPLFPGKNDIEQLCYVLRILGTPNPQVWPELTELPDYNK 239

Query: 239 YPM-YPATTSLVNVVPKLNATGRDLLQNLLKCNPVQRISAEEALQHPYF 286
                     L  V+P ++    DLL   L   P QRI+A +AL H YF
Sbjct: 240 ISFKEQVPMPLEEVLPDVSPQALDLLGQFLLYPPHQRIAASKALLHQYF 288


>gi|157817073 Cdc2-related kinase, arginine/serine-rich isoform 2
            [Homo sapiens]
          Length = 1481

 Score =  224 bits (571), Expect = 7e-59
 Identities = 123/303 (40%), Positives = 189/303 (62%), Gaps = 19/303 (6%)

Query: 1    MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKH 60
            + K++ +  IGEGTYG V+KAK+++T E+VALK+VRLD++ EG P +A+REI +L++L H
Sbjct: 724  VDKFDIIGIIGEGTYGQVYKAKDKDTGELVALKKVRLDNEKEGFPITAIREIKILRQLIH 783

Query: 61   KNIVRLHDVLHSDKK-----------LTLVFEFCDQDLKKYFDSCNGDLDPEIVKSFLFQ 109
            +++V + +++ +DK+             LVFE+ D DL    +S       + +KSF+ Q
Sbjct: 784  RSVVNMKEIV-TDKQDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFSEDHIKSFMKQ 842

Query: 110  LLKGLGFCHSRNVLHRDLKPQNLLINRNGELKLADFGLARAFGI-PVRCYSAEVVTLWYR 168
            L++GL +CH +N LHRD+K  N+L+N +G++KLADFGLAR +     R Y+ +V+TLWYR
Sbjct: 843  LMEGLEYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYNSEESRPYTNKVITLWYR 902

Query: 169  PPDVLFGAKLYSTSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIFRLLGTPTEEQWP 228
            PP++L G + Y+ +ID+WS GCI  EL    +P+F  N    QL+ I RL G+P    WP
Sbjct: 903  PPELLLGEERYTPAIDVWSCGCILGELFTK-KPIFQANLELAQLELISRLCGSPCPAVWP 961

Query: 229  SMTKLPDY---KPYPMYPATTSLVNVVPKLNATGRDLLQNLLKCNPVQRISAEEALQHPY 285
             + KLP +   KP   Y     L      + +   DLL ++L  +P +R +AE+ LQ  +
Sbjct: 962  DVIKLPYFNTMKPKKQY--RRRLREEFSFIPSAALDLLDHMLTLDPSKRCTAEQTLQSDF 1019

Query: 286  FSD 288
              D
Sbjct: 1020 LKD 1022


>gi|157817023 Cdc2-related kinase, arginine/serine-rich isoform 1
            [Homo sapiens]
          Length = 1490

 Score =  224 bits (571), Expect = 7e-59
 Identities = 123/303 (40%), Positives = 189/303 (62%), Gaps = 19/303 (6%)

Query: 1    MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKH 60
            + K++ +  IGEGTYG V+KAK+++T E+VALK+VRLD++ EG P +A+REI +L++L H
Sbjct: 724  VDKFDIIGIIGEGTYGQVYKAKDKDTGELVALKKVRLDNEKEGFPITAIREIKILRQLIH 783

Query: 61   KNIVRLHDVLHSDKK-----------LTLVFEFCDQDLKKYFDSCNGDLDPEIVKSFLFQ 109
            +++V + +++ +DK+             LVFE+ D DL    +S       + +KSF+ Q
Sbjct: 784  RSVVNMKEIV-TDKQDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFSEDHIKSFMKQ 842

Query: 110  LLKGLGFCHSRNVLHRDLKPQNLLINRNGELKLADFGLARAFGI-PVRCYSAEVVTLWYR 168
            L++GL +CH +N LHRD+K  N+L+N +G++KLADFGLAR +     R Y+ +V+TLWYR
Sbjct: 843  LMEGLEYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYNSEESRPYTNKVITLWYR 902

Query: 169  PPDVLFGAKLYSTSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIFRLLGTPTEEQWP 228
            PP++L G + Y+ +ID+WS GCI  EL    +P+F  N    QL+ I RL G+P    WP
Sbjct: 903  PPELLLGEERYTPAIDVWSCGCILGELFTK-KPIFQANLELAQLELISRLCGSPCPAVWP 961

Query: 229  SMTKLPDY---KPYPMYPATTSLVNVVPKLNATGRDLLQNLLKCNPVQRISAEEALQHPY 285
             + KLP +   KP   Y     L      + +   DLL ++L  +P +R +AE+ LQ  +
Sbjct: 962  DVIKLPYFNTMKPKKQY--RRRLREEFSFIPSAALDLLDHMLTLDPSKRCTAEQTLQSDF 1019

Query: 286  FSD 288
              D
Sbjct: 1020 LKD 1022


>gi|4502735 cyclin-dependent kinase 4 [Homo sapiens]
          Length = 303

 Score =  224 bits (570), Expect = 9e-59
 Identities = 131/295 (44%), Positives = 177/295 (60%), Gaps = 17/295 (5%)

Query: 3   KYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEG---VPSSALREICLLKELK 59
           +YE + +IG G YGTV+KA++  +   VALK VR+ +   G   +P S +RE+ LL+ L+
Sbjct: 5   RYEPVAEIGVGAYGTVYKARDPHSGHFVALKSVRVPNGGGGGGGLPISTVREVALLRRLE 64

Query: 60  ---HKNIVRLHDVLHSDK-----KLTLVFEFCDQDLKKYFDSCNGD-LDPEIVKSFLFQL 110
              H N+VRL DV  + +     K+TLVFE  DQDL+ Y D      L  E +K  + Q 
Sbjct: 65  AFEHPNVVRLMDVCATSRTDREIKVTLVFEHVDQDLRTYLDKAPPPGLPAETIKDLMRQF 124

Query: 111 LKGLGFCHSRNVLHRDLKPQNLLINRNGELKLADFGLARAFGIPVRCYSAEVVTLWYRPP 170
           L+GL F H+  ++HRDLKP+N+L+   G +KLADFGLAR +   +   +  VVTLWYR P
Sbjct: 125 LRGLDFLHANCIVHRDLKPENILVTSGGTVKLADFGLARIYSYQM-ALTPVVVTLWYRAP 183

Query: 171 DVLFGAKLYSTSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIFRLLGTPTEEQWPSM 230
           +VL     Y+T +DMWS GCIFAE+    +PLF GN   DQL +IF L+G P E+ WP  
Sbjct: 184 EVLL-QSTYATPVDMWSVGCIFAEMFRR-KPLFCGNSEADQLGKIFDLIGLPPEDDWPRD 241

Query: 231 TKLPDYKPYPMYPATTSLVNVVPKLNATGRDLLQNLLKCNPVQRISAEEALQHPY 285
             LP     P  P      +VVP++  +G  LL  +L  NP +RISA  ALQH Y
Sbjct: 242 VSLPRGAFPPRGPRPVQ--SVVPEMEESGAQLLLEMLTFNPHKRISAFRALQHSY 294


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.140    0.432 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,756,355
Number of Sequences: 37866
Number of extensions: 550338
Number of successful extensions: 3539
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 738
Number of HSP's successfully gapped in prelim test: 46
Number of HSP's that attempted gapping in prelim test: 1172
Number of HSP's gapped (non-prelim): 981
length of query: 292
length of database: 18,247,518
effective HSP length: 101
effective length of query: 191
effective length of database: 14,423,052
effective search space: 2754802932
effective search space used: 2754802932
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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