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Search of human proteins with 48255883
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|48255883 troponin T type 2, cardiac isoform 4 [Homo sapiens]
(282 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|48255883 troponin T type 2, cardiac isoform 4 [Homo sapiens] 555 e-158
gi|48255879 troponin T type 2, cardiac isoform 2 [Homo sapiens] 544 e-155
gi|48255881 troponin T type 2, cardiac isoform 3 [Homo sapiens] 540 e-154
gi|48255877 troponin T type 2, cardiac isoform 1 [Homo sapiens] 536 e-153
gi|187173290 troponin T1, skeletal, slow isoform b [Homo sapiens] 318 4e-87
gi|187173292 troponin T1, skeletal, slow isoform c [Homo sapiens] 315 3e-86
gi|187173288 troponin T1, skeletal, slow isoform a [Homo sapiens] 307 6e-84
gi|5803203 troponin T3, skeletal, fast isoform 1 [Homo sapiens] 305 4e-83
gi|112789541 troponin T3, skeletal, fast isoform 4 [Homo sapiens] 297 8e-81
gi|112789538 troponin T3, skeletal, fast isoform 2 [Homo sapiens] 296 1e-80
gi|112789536 troponin T3, skeletal, fast isoform 3 [Homo sapiens] 289 2e-78
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 76 4e-14
gi|239749449 PREDICTED: hypothetical protein [Homo sapiens] 72 4e-13
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] 72 4e-13
gi|55741709 RNA binding motif protein 25 [Homo sapiens] 72 5e-13
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 72 5e-13
gi|50726968 microfibrillar-associated protein 1 [Homo sapiens] 72 7e-13
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 71 9e-13
gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ... 70 2e-12
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 69 4e-12
gi|102467235 inner centromere protein antigens 135/155kDa isofor... 68 8e-12
gi|102467242 inner centromere protein antigens 135/155kDa isofor... 68 8e-12
gi|148746195 trichohyalin [Homo sapiens] 68 1e-11
gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi... 67 1e-11
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 67 1e-11
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 67 2e-11
gi|155030232 proline, glutamic acid and leucine rich protein 1 [... 67 2e-11
gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sap... 66 3e-11
gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sap... 66 3e-11
gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo sap... 66 3e-11
>gi|48255883 troponin T type 2, cardiac isoform 4 [Homo sapiens]
Length = 282
Score = 555 bits (1429), Expect = e-158
Identities = 282/282 (100%), Positives = 282/282 (100%)
Query: 1 MSDIEEVVEEYEEEEQEEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDGPMEESKP 60
MSDIEEVVEEYEEEEQEEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDGPMEESKP
Sbjct: 1 MSDIEEVVEEYEEEEQEEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDGPMEESKP 60
Query: 61 KPRSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHFENRKKEEEELVSLKD 120
KPRSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHFENRKKEEEELVSLKD
Sbjct: 61 KPRSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHFENRKKEEEELVSLKD 120
Query: 121 RIERRRAERAEQQRIRNEREKERQNRLAEERARREEEENRRKAEDEARKKKALSNMMHFG 180
RIERRRAERAEQQRIRNEREKERQNRLAEERARREEEENRRKAEDEARKKKALSNMMHFG
Sbjct: 121 RIERRRAERAEQQRIRNEREKERQNRLAEERARREEEENRRKAEDEARKKKALSNMMHFG 180
Query: 181 GYIQKAQTERKSGKRQTEREKKKKILAERRKVLAIDHLNEDQLREKAKELWQSIYNLEAE 240
GYIQKAQTERKSGKRQTEREKKKKILAERRKVLAIDHLNEDQLREKAKELWQSIYNLEAE
Sbjct: 181 GYIQKAQTERKSGKRQTEREKKKKILAERRKVLAIDHLNEDQLREKAKELWQSIYNLEAE 240
Query: 241 KFDLQEKFKQQKYEINVLRNRINDNQKVSKTRGKAKVTGRWK 282
KFDLQEKFKQQKYEINVLRNRINDNQKVSKTRGKAKVTGRWK
Sbjct: 241 KFDLQEKFKQQKYEINVLRNRINDNQKVSKTRGKAKVTGRWK 282
>gi|48255879 troponin T type 2, cardiac isoform 2 [Homo sapiens]
Length = 288
Score = 544 bits (1401), Expect = e-155
Identities = 282/288 (97%), Positives = 282/288 (97%), Gaps = 6/288 (2%)
Query: 1 MSDIEEVVEEYEEEEQEE-----QEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDGPM 55
MSDIEEVVEEYEEEEQEE QEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDGPM
Sbjct: 1 MSDIEEVVEEYEEEEQEEAAVEEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDGPM 60
Query: 56 EESKPKPRSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHFENRKKEEEEL 115
EESKPKPRSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHFENRKKEEEEL
Sbjct: 61 EESKPKPRSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHFENRKKEEEEL 120
Query: 116 VSLKDRIERRRAERAEQQRIRNEREKERQNRLAEERARREEEENRRKAEDEARKKKALSN 175
VSLKDRIERRRAERAEQQRIRNEREKERQNRLAEERARREEEENRRKAEDEARKKKALSN
Sbjct: 121 VSLKDRIERRRAERAEQQRIRNEREKERQNRLAEERARREEEENRRKAEDEARKKKALSN 180
Query: 176 MMHFGGYIQK-AQTERKSGKRQTEREKKKKILAERRKVLAIDHLNEDQLREKAKELWQSI 234
MMHFGGYIQK AQTERKSGKRQTEREKKKKILAERRKVLAIDHLNEDQLREKAKELWQSI
Sbjct: 181 MMHFGGYIQKQAQTERKSGKRQTEREKKKKILAERRKVLAIDHLNEDQLREKAKELWQSI 240
Query: 235 YNLEAEKFDLQEKFKQQKYEINVLRNRINDNQKVSKTRGKAKVTGRWK 282
YNLEAEKFDLQEKFKQQKYEINVLRNRINDNQKVSKTRGKAKVTGRWK
Sbjct: 241 YNLEAEKFDLQEKFKQQKYEINVLRNRINDNQKVSKTRGKAKVTGRWK 288
>gi|48255881 troponin T type 2, cardiac isoform 3 [Homo sapiens]
Length = 285
Score = 540 bits (1391), Expect = e-154
Identities = 280/287 (97%), Positives = 280/287 (97%), Gaps = 7/287 (2%)
Query: 1 MSDIEEVVEEYEEEEQEE-----QEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDGPM 55
MSDIEEVVEEYEEEEQEE QEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDGPM
Sbjct: 1 MSDIEEVVEEYEEEEQEEAAVEEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDGPM 60
Query: 56 EESKPKPRSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHFENRKKEEEEL 115
EESKPKPRSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHFENRKKEEEEL
Sbjct: 61 EESKPKPRSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHFENRKKEEEEL 120
Query: 116 VSLKDRIERRRAERAEQQRIRNEREKERQNRLAEERARREEEENRRKAEDEARKKKALSN 175
VSLKDRIERRRAERAEQQRIRNEREKERQNRLAEERARREEEENRRKAEDEARKKKALSN
Sbjct: 121 VSLKDRIERRRAERAEQQRIRNEREKERQNRLAEERARREEEENRRKAEDEARKKKALSN 180
Query: 176 MMHFGGYIQKAQTERKSGKRQTEREKKKKILAERRKVLAIDHLNEDQLREKAKELWQSIY 235
MMHFGGYIQK TERKSGKRQTEREKKKKILAERRKVLAIDHLNEDQLREKAKELWQSIY
Sbjct: 181 MMHFGGYIQK--TERKSGKRQTEREKKKKILAERRKVLAIDHLNEDQLREKAKELWQSIY 238
Query: 236 NLEAEKFDLQEKFKQQKYEINVLRNRINDNQKVSKTRGKAKVTGRWK 282
NLEAEKFDLQEKFKQQKYEINVLRNRINDNQKVSKTRGKAKVTGRWK
Sbjct: 239 NLEAEKFDLQEKFKQQKYEINVLRNRINDNQKVSKTRGKAKVTGRWK 285
>gi|48255877 troponin T type 2, cardiac isoform 1 [Homo sapiens]
Length = 295
Score = 536 bits (1381), Expect = e-153
Identities = 280/297 (94%), Positives = 280/297 (94%), Gaps = 17/297 (5%)
Query: 1 MSDIEEVVEEYEEEEQEE---------------QEEAAEEDAEAEAETEETRAEEDEEEE 45
MSDIEEVVEEYEEEEQEE QEEAAEEDAEAEAETEETRAEEDEEEE
Sbjct: 1 MSDIEEVVEEYEEEEQEEAAVEEEEDWREDEDEQEEAAEEDAEAEAETEETRAEEDEEEE 60
Query: 46 EAKEAEDGPMEESKPKPRSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHF 105
EAKEAEDGPMEESKPKPRSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHF
Sbjct: 61 EAKEAEDGPMEESKPKPRSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHF 120
Query: 106 ENRKKEEEELVSLKDRIERRRAERAEQQRIRNEREKERQNRLAEERARREEEENRRKAED 165
ENRKKEEEELVSLKDRIERRRAERAEQQRIRNEREKERQNRLAEERARREEEENRRKAED
Sbjct: 121 ENRKKEEEELVSLKDRIERRRAERAEQQRIRNEREKERQNRLAEERARREEEENRRKAED 180
Query: 166 EARKKKALSNMMHFGGYIQKAQTERKSGKRQTEREKKKKILAERRKVLAIDHLNEDQLRE 225
EARKKKALSNMMHFGGYIQK TERKSGKRQTEREKKKKILAERRKVLAIDHLNEDQLRE
Sbjct: 181 EARKKKALSNMMHFGGYIQK--TERKSGKRQTEREKKKKILAERRKVLAIDHLNEDQLRE 238
Query: 226 KAKELWQSIYNLEAEKFDLQEKFKQQKYEINVLRNRINDNQKVSKTRGKAKVTGRWK 282
KAKELWQSIYNLEAEKFDLQEKFKQQKYEINVLRNRINDNQKVSKTRGKAKVTGRWK
Sbjct: 239 KAKELWQSIYNLEAEKFDLQEKFKQQKYEINVLRNRINDNQKVSKTRGKAKVTGRWK 295
>gi|187173290 troponin T1, skeletal, slow isoform b [Homo sapiens]
Length = 262
Score = 318 bits (814), Expect = 4e-87
Identities = 176/284 (61%), Positives = 211/284 (74%), Gaps = 24/284 (8%)
Query: 1 MSDIEEVVEEYEEEEQEEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDGPMEESKP 60
MSD EE +EYEEE+ EE EAAEE+ EA E E E+E +P
Sbjct: 1 MSDTEE--QEYEEEQPEE--EAAEEEEEAPEEPEPVAEPEEE----------------RP 40
Query: 61 KP-RSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHFENRKKEEEELVSLK 119
KP R +P L+PPKIP+GERVDFDDIHRKRMEKDL ELQ LI+ HFE RKKEEEELV+LK
Sbjct: 41 KPSRPVVPPLIPPKIPEGERVDFDDIHRKRMEKDLLELQTLIDVHFEQRKKEEEELVALK 100
Query: 120 DRIERRRAERAEQQRIRNEREKERQNRLAEERARREEEENRRKAEDEARKKKALSNM-MH 178
+RIERRR+ERAEQQR R E+E+ERQ +LAEE+ R+EEEE +++AED+A+KKK LSNM H
Sbjct: 101 ERIERRRSERAEQQRFRTEKERERQAKLAEEKMRKEEEEAKKRAEDDAKKKKVLSNMGAH 160
Query: 179 FGGYIQKAQTERKSGKRQTEREKKKKILAERRKVLAIDHLNEDQLREKAKELWQSIYNLE 238
FGGY+ KA E+K GKRQT RE K +IL+ER+K L ID++ E+QLREKA+EL I+ LE
Sbjct: 161 FGGYLVKA--EQKRGKRQTGREMKVRILSERKKPLDIDYMGEEQLREKAQELSDWIHQLE 218
Query: 239 AEKFDLQEKFKQQKYEINVLRNRINDNQKVSKTRGKAKVTGRWK 282
+EKFDL K KQQKYEINVL NRI+ QK K GK +V GRWK
Sbjct: 219 SEKFDLMAKLKQQKYEINVLYNRISHAQKFRKGAGKGRVGGRWK 262
>gi|187173292 troponin T1, skeletal, slow isoform c [Homo sapiens]
Length = 251
Score = 315 bits (807), Expect = 3e-86
Identities = 166/254 (65%), Positives = 202/254 (79%), Gaps = 6/254 (2%)
Query: 31 AETEETRAEEDEEEEEAKEAEDGPMEESKPKP-RSFMPNLVPPKIPDGERVDFDDIHRKR 89
++TEE EE++ EEEA E E+ EE +PKP R +P L+PPKIP+GERVDFDDIHRKR
Sbjct: 2 SDTEEQEYEEEQPEEEAAEEEEE--EEERPKPSRPVVPPLIPPKIPEGERVDFDDIHRKR 59
Query: 90 MEKDLNELQALIEAHFENRKKEEEELVSLKDRIERRRAERAEQQRIRNEREKERQNRLAE 149
MEKDL ELQ LI+ HFE RKKEEEELV+LK+RIERRR+ERAEQQR R E+E+ERQ +LAE
Sbjct: 60 MEKDLLELQTLIDVHFEQRKKEEEELVALKERIERRRSERAEQQRFRTEKERERQAKLAE 119
Query: 150 ERARREEEENRRKAEDEARKKKALSNM-MHFGGYIQKAQTERKSGKRQTEREKKKKILAE 208
E+ R+EEEE +++AED+A+KKK LSNM HFGGY+ KA E+K GKRQT RE K +IL+E
Sbjct: 120 EKMRKEEEEAKKRAEDDAKKKKVLSNMGAHFGGYLVKA--EQKRGKRQTGREMKVRILSE 177
Query: 209 RRKVLAIDHLNEDQLREKAKELWQSIYNLEAEKFDLQEKFKQQKYEINVLRNRINDNQKV 268
R+K L ID++ E+QLREKA+EL I+ LE+EKFDL K KQQKYEINVL NRI+ QK
Sbjct: 178 RKKPLDIDYMGEEQLREKAQELSDWIHQLESEKFDLMAKLKQQKYEINVLYNRISHAQKF 237
Query: 269 SKTRGKAKVTGRWK 282
K GK +V GRWK
Sbjct: 238 RKGAGKGRVGGRWK 251
>gi|187173288 troponin T1, skeletal, slow isoform a [Homo sapiens]
Length = 278
Score = 307 bits (787), Expect = 6e-84
Identities = 176/300 (58%), Positives = 211/300 (70%), Gaps = 40/300 (13%)
Query: 1 MSDIEEVVEEYEEEEQEEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDGPMEESKP 60
MSD EE +EYEEE+ EE EAAEE+ EA E E E+E +P
Sbjct: 1 MSDTEE--QEYEEEQPEE--EAAEEEEEAPEEPEPVAEPEEE----------------RP 40
Query: 61 KP-RSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHFENRKKEEEELVSLK 119
KP R +P L+PPKIP+GERVDFDDIHRKRMEKDL ELQ LI+ HFE RKKEEEELV+LK
Sbjct: 41 KPSRPVVPPLIPPKIPEGERVDFDDIHRKRMEKDLLELQTLIDVHFEQRKKEEEELVALK 100
Query: 120 DRIERRRAERAEQQRIRNEREKERQNRLAEERARREEEENRRKAEDEARKKKALSNM-MH 178
+RIERRR+ERAEQQR R E+E+ERQ +LAEE+ R+EEEE +++AED+A+KKK LSNM H
Sbjct: 101 ERIERRRSERAEQQRFRTEKERERQAKLAEEKMRKEEEEAKKRAEDDAKKKKVLSNMGAH 160
Query: 179 FGGYIQKAQTERKSGKRQTEREKKKKILAERRKVLAIDHLNEDQL--------------- 223
FGGY+ KA E+K GKRQT RE K +IL+ER+K L ID++ E+QL
Sbjct: 161 FGGYLVKA--EQKRGKRQTGREMKVRILSERKKPLDIDYMGEEQLRARSAWLPPSQPSCP 218
Query: 224 -REKAKELWQSIYNLEAEKFDLQEKFKQQKYEINVLRNRINDNQKVSKTRGKAKVTGRWK 282
REKA+EL I+ LE+EKFDL K KQQKYEINVL NRI+ QK K GK +V GRWK
Sbjct: 219 AREKAQELSDWIHQLESEKFDLMAKLKQQKYEINVLYNRISHAQKFRKGAGKGRVGGRWK 278
>gi|5803203 troponin T3, skeletal, fast isoform 1 [Homo sapiens]
Length = 258
Score = 305 bits (780), Expect = 4e-83
Identities = 166/284 (58%), Positives = 209/284 (73%), Gaps = 34/284 (11%)
Query: 3 DIEEVVEEYEEEEQEEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDGPMEESKPKP 62
++E+V E+YEEEE+ ++EE +ED AEED EEE KP
Sbjct: 5 EVEQVEEQYEEEEEAQEEEEVQEDT----------AEEDAEEE---------------KP 39
Query: 63 RSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHFENRKKEEEELVSLKDRI 122
R P L PKIP+GE+VDFDDI +KR KDL ELQALI++HFE RKKEEEELV+LK+RI
Sbjct: 40 R---PKLTAPKIPEGEKVDFDDIQKKRQNKDLMELQALIDSHFEARKKEEEELVALKERI 96
Query: 123 ERRRAERAEQQRIRNEREKERQNRLAEERARREEEENRRKAEDEARKKKALSNM-MHFGG 181
E+RRAERAEQQRIR E+E+ERQNRLAEE+ARREEE+ +R+AED+ +KKKALS+M ++
Sbjct: 97 EKRRAERAEQQRIRAEKERERQNRLAEEKARREEEDAKRRAEDDLKKKKALSSMGANYSS 156
Query: 182 YIQKAQTERKSGKRQTEREKKKKILAERRKVLAIDHLNEDQLREKAKELWQSIYNLEAEK 241
Y+ KA ++K GK+QT RE KKKILAERRK L IDHL ED+LR+KAKELW++++ LE +K
Sbjct: 157 YLAKA--DQKRGKKQTAREMKKKILAERRKPLNIDHLGEDKLRDKAKELWETLHQLEIDK 214
Query: 242 FDLQEKFKQQKYEINVLRNRINDNQKVSKTRG---KAKVTGRWK 282
F+ EK K+QKY+I LR+RI+ QK SK G K KV GRWK
Sbjct: 215 FEFGEKLKRQKYDITTLRSRIDQAQKHSKKAGTPAKGKVGGRWK 258
>gi|112789541 troponin T3, skeletal, fast isoform 4 [Homo sapiens]
Length = 250
Score = 297 bits (760), Expect = 8e-81
Identities = 156/256 (60%), Positives = 198/256 (77%), Gaps = 11/256 (4%)
Query: 31 AETEETRAEEDEEEEEAKEAEDGPMEESKPKPRSFMPNLVPPKIPDGERVDFDDIHRKRM 90
++ E + EE EEEE + E+ EE KP+P+ L PKIP+GE+VDFDDI +KR
Sbjct: 2 SDEEVEQVEEQYEEEEEAQEEEEVQEEEKPRPK-----LTAPKIPEGEKVDFDDIQKKRQ 56
Query: 91 EKDLNELQALIEAHFENRKKEEEELVSLKDRIERRRAERAEQQRIRNEREKERQNRLAEE 150
KDL ELQALI++HFE RKKEEEELV+LK+RIE+RRAERAEQQRIR E+E+ERQNRLAEE
Sbjct: 57 NKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRLAEE 116
Query: 151 RARREEEENRRKAEDEARKKKALSNM-MHFGGYIQKAQTERKSGKRQTEREKKKKILAER 209
+ARREEE+ +R+AED+ +KKKALS+M ++ Y+ KA ++K GK+QT RE KKKILAER
Sbjct: 117 KARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKA--DQKRGKKQTAREMKKKILAER 174
Query: 210 RKVLAIDHLNEDQLREKAKELWQSIYNLEAEKFDLQEKFKQQKYEINVLRNRINDNQKVS 269
RK L IDHL ED+LR+KAKELW++++ LE +KF+ EK K+QKY+I LR+RI+ QK S
Sbjct: 175 RKPLNIDHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDITTLRSRIDQAQKHS 234
Query: 270 KTRG---KAKVTGRWK 282
K G K KV GRWK
Sbjct: 235 KKAGTPAKGKVGGRWK 250
>gi|112789538 troponin T3, skeletal, fast isoform 2 [Homo sapiens]
Length = 256
Score = 296 bits (759), Expect = 1e-80
Identities = 162/274 (59%), Positives = 201/274 (73%), Gaps = 24/274 (8%)
Query: 13 EEEQEEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDGPMEESKPKPRSFMPNLVPP 72
+EE E+ EE EE+ EA+ E E E E EE KPR P L P
Sbjct: 3 DEEVEQVEEQYEEEEEAQEEAAEVHEEVHEPEE---------------KPR---PKLTAP 44
Query: 73 KIPDGERVDFDDIHRKRMEKDLNELQALIEAHFENRKKEEEELVSLKDRIERRRAERAEQ 132
KIP+GE+VDFDDI +KR KDL ELQALI++HFE RKKEEEELV+LK+RIE+RRAERAEQ
Sbjct: 45 KIPEGEKVDFDDIQKKRQNKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQ 104
Query: 133 QRIRNEREKERQNRLAEERARREEEENRRKAEDEARKKKALSNM-MHFGGYIQKAQTERK 191
QRIR E+E+ERQNRLAEE+ARREEE+ +R+AED+ +KKKALS+M ++ Y+ KA ++K
Sbjct: 105 QRIRAEKERERQNRLAEEKARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKA--DQK 162
Query: 192 SGKRQTEREKKKKILAERRKVLAIDHLNEDQLREKAKELWQSIYNLEAEKFDLQEKFKQQ 251
GK+QT RE KKKILAERRK L IDHL ED+LR+KAKELW++++ LE +KF+ EK K+Q
Sbjct: 163 RGKKQTAREMKKKILAERRKPLNIDHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQ 222
Query: 252 KYEINVLRNRINDNQKVSKTRG---KAKVTGRWK 282
KY+I LR+RI+ QK SK G K KV GRWK
Sbjct: 223 KYDITTLRSRIDQAQKHSKKAGTPAKGKVGGRWK 256
>gi|112789536 troponin T3, skeletal, fast isoform 3 [Homo sapiens]
Length = 250
Score = 289 bits (739), Expect = 2e-78
Identities = 153/256 (59%), Positives = 195/256 (76%), Gaps = 11/256 (4%)
Query: 31 AETEETRAEEDEEEEEAKEAEDGPMEESKPKPRSFMPNLVPPKIPDGERVDFDDIHRKRM 90
++ E + EE EEEE + E+ EE KP+P+ L PKIP+GE+VDFDDI +KR
Sbjct: 2 SDEEVEQVEEQYEEEEEAQEEEEVQEEEKPRPK-----LTAPKIPEGEKVDFDDIQKKRQ 56
Query: 91 EKDLNELQALIEAHFENRKKEEEELVSLKDRIERRRAERAEQQRIRNEREKERQNRLAEE 150
KDL ELQALI++HFE RKKEEEELV+LK+RIE+RRAERAEQQRIR E+E+ERQNRLAEE
Sbjct: 57 NKDLMELQALIDSHFEARKKEEEELVALKERIEKRRAERAEQQRIRAEKERERQNRLAEE 116
Query: 151 RARREEEENRRKAEDEARKKKALSNM-MHFGGYIQKAQTERKSGKRQTEREKKKKILAER 209
+ARREEE+ +R+AED+ +KKKALS+M ++ Y+ KA ++K GK+QT RE KKKILAER
Sbjct: 117 KARREEEDAKRRAEDDLKKKKALSSMGANYSSYLAKA--DQKRGKKQTAREMKKKILAER 174
Query: 210 RKVLAIDHLNEDQLREKAKELWQSIYNLEAEKFDLQEKFKQQKYEINVLRNRINDNQKVS 269
RK L IDHL ED+LR+KAKELW++++ LE +KF+ EK K+QKY+I +R R+ K S
Sbjct: 175 RKPLNIDHLGEDKLRDKAKELWETLHQLEIDKFEFGEKLKRQKYDIMNVRARVQMLAKFS 234
Query: 270 KTRG---KAKVTGRWK 282
K G K KV GRWK
Sbjct: 235 KKAGTPAKGKVGGRWK 250
>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
Length = 245
Score = 75.9 bits (185), Expect = 4e-14
Identities = 61/217 (28%), Positives = 102/217 (47%), Gaps = 21/217 (9%)
Query: 19 QEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDGPMEESKPKPRSFMPNLVPPKIPDGE 78
Q E E + E E E + E E ++E +E E E K + R K GE
Sbjct: 35 QSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRER-----GKKEKKGE 89
Query: 79 RVDFDDIHRKRMEKDLNELQALIEAHFENRKKEE----EELVSLKDRIERRRAERAEQQR 134
R + +KR + N+ E + KKE +E + + ER+R ER E++R
Sbjct: 90 RKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERER 149
Query: 135 IRNEREKERQNRLAEERARR---EEEENRRKAEDEARKKKALSNMMHFGGYIQKAQTERK 191
+ EREKER+ + ++R R+ E+EE R++ E + RKK+ + +K + + +
Sbjct: 150 KKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERN---------RKERKKER 200
Query: 192 SGKRQTEREKKKKILAERRKVLAIDHLNEDQLREKAK 228
K + ER+K++K ER+K D + +E+ K
Sbjct: 201 ERKERRERKKERKKKEERKKERQKDRQTNWREKERGK 237
Score = 68.2 bits (165), Expect = 8e-12
Identities = 52/195 (26%), Positives = 94/195 (48%), Gaps = 26/195 (13%)
Query: 13 EEEQEEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEAED---GPMEESKPKPRSFMPNL 69
E E+E + E +++ + E + EE ++ E+E KE E+ +E K + R+
Sbjct: 72 EREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGK 131
Query: 70 VPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHFENRKKEEEELVSLK--DRIERRRA 127
+ + +R + + RK+ E++ E + RKK E + V K +R E+ R
Sbjct: 132 ERERKEERKREERKERERKKEEREK-------ERERKERKKRERKQVGEKEEERKEKERK 184
Query: 128 ERAEQQRIRNEREKERQNRLAEERARREEEENRRKAEDEARKKKALSNMMHFGGYIQKAQ 187
ER +++R R ER+KER ER R E + RK ++E +K++ ++
Sbjct: 185 ERKKRERNRKERKKER------ERKERRERKKERKKKEERKKERQKDRQTNW-------- 230
Query: 188 TERKSGKRQTEREKK 202
E++ GKR+ + KK
Sbjct: 231 REKERGKRERKERKK 245
Score = 65.5 bits (158), Expect = 5e-11
Identities = 58/211 (27%), Positives = 101/211 (47%), Gaps = 19/211 (9%)
Query: 91 EKDLNELQALIEAHFENRKKEEEELVSLKDRIERRRAER-AEQQRIRNEREK--ERQNRL 147
+ ++ E + IE E +K+ E E + E+R+ ER E++R R ++EK ER+
Sbjct: 35 QSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEE 94
Query: 148 AEERARREEEENRRKAEDEARKKKALSNMMHFG------------GYIQKAQTERKSGKR 195
E + RR E+EN+ E E RKKK ++ + ERK +R
Sbjct: 95 RERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEER 154
Query: 196 QTEREKKKKILAERRKVLAIDHLNEDQLRE--KAKELWQSIYNLEAEKFDLQEKFKQQKY 253
+ ERE+K++ ER++V + +++ R+ K +E + E E+ + +E+ K++K
Sbjct: 155 EKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKK 214
Query: 254 EINVLRNRINDNQK--VSKTRGKAKVTGRWK 282
+ + R D Q K RGK + R K
Sbjct: 215 KEERKKERQKDRQTNWREKERGKRERKERKK 245
Score = 55.1 bits (131), Expect = 7e-08
Identities = 47/159 (29%), Positives = 78/159 (49%), Gaps = 26/159 (16%)
Query: 6 EVVEEYEEEEQEEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDGPMEESKPKPRSF 65
E E+ +++E++E+ ++E E E + EE + EE +E E KE + E + K R
Sbjct: 110 EEKEKRKKKEKKERGRTSKEGKERERK-EERKREERKERERKKEEREKERERKERKKR-- 166
Query: 66 MPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHFENRKKEEEELVSLKDRIER- 124
ER + +R EK+ E + E + + RKKE E R ER
Sbjct: 167 ------------ERKQVGEKEEERKEKERKERKKR-ERNRKERKKERE-------RKERR 206
Query: 125 -RRAERAEQQRIRNEREKERQNRLAE-ERARREEEENRR 161
R+ ER +++ + ER+K+RQ E ER +RE +E ++
Sbjct: 207 ERKKERKKKEERKKERQKDRQTNWREKERGKRERKERKK 245
>gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]
Length = 275
Score = 72.4 bits (176), Expect = 4e-13
Identities = 63/266 (23%), Positives = 119/266 (44%), Gaps = 34/266 (12%)
Query: 12 EEEEQEEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDGPMEESKPKPRSFMPNLVP 71
+ E + ++E E + E E E R +E+++ K+ E G E K K R
Sbjct: 31 QRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKER-------- 82
Query: 72 PKIPDGERVDFDDIHRKRMEKDLNELQALIEAHFENRKKEEEELVSLKDRIERRRAERAE 131
+ +R + + R++ +K+ + + E +KK+E + ++R ++R ER
Sbjct: 83 ----EKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKE---RERENKQRRERKR 135
Query: 132 QQRIRNEREKERQNRLAEERARREEEENRRKAEDEARKKKALSNMMHFGGYIQKAQTERK 191
++R + +R KER+ +ER +RE + +RK E+ R+KK N ++ + +
Sbjct: 136 KKRRKKKRRKERKRE--KERGKRERKRKKRKKEE--REKKRERNRKERKKERERKERRER 191
Query: 192 SGKRQTEREKKKKILAERRKVLAIDHLNEDQ----LREKAKE-------LWQSIYNLEAE 240
+R+ ER KKK ER+K D + Q LRE A I++ +
Sbjct: 192 KKERKKERRKKK----ERKKDRKTDRQTDSQVFRPLRESAFNRVTVTGVFRYRIFHTGLD 247
Query: 241 KFDLQEKFKQQKYEINVLRNRINDNQ 266
F ++ ++E+N +ND +
Sbjct: 248 HFPIKTNILLSRHEVNDGEIEVNDGE 273
Score = 60.1 bits (144), Expect = 2e-09
Identities = 48/185 (25%), Positives = 91/185 (49%), Gaps = 28/185 (15%)
Query: 102 EAHFENRKKEEEELVSLKDRIERRRAERA-EQQRIRNEREKERQNRLAEERARREEEENR 160
E R+KE + K++ +R++ ER E++R R EREK+R+ R +ER +R++E+ +
Sbjct: 44 EKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERRKRKKEKKK 103
Query: 161 RKAEDEARKKKALSNMMHFGGYIQKAQTERK----SGKRQTEREKKKKILAERRKVLAID 216
R+ + R+++ K + ERK K++ ER++KK+ +RRK +
Sbjct: 104 RERKQRGRRER-------------KKKKERKERERENKQRRERKRKKRRKKKRRKERKRE 150
Query: 217 ----------HLNEDQLREKAKELWQSIYNLEAEKFDLQEKFKQQKYEINVLRNRINDNQ 266
+ + REK +E + E E+ + +E+ K++K E + R D +
Sbjct: 151 KERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKERKKDRK 210
Query: 267 KVSKT 271
+T
Sbjct: 211 TDRQT 215
Score = 49.3 bits (116), Expect = 4e-06
Identities = 38/156 (24%), Positives = 74/156 (47%), Gaps = 8/156 (5%)
Query: 124 RRRAERAEQQRIRNEREKERQNRLAEERARREEEENRRKAEDEARKKKALSNMMHFGGYI 183
+R +ER +++R R +R++ER+ ER ++E+++ +++ + R++K
Sbjct: 31 QRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERR 90
Query: 184 QKAQTERKSGKRQTERE-------KKKKILAERRKVLAIDHLNEDQLREKAKELWQSIYN 236
+K + +RK K++ ER+ KKKK ER + + + R K K +
Sbjct: 91 EKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKRE 150
Query: 237 LEAEKFDLQEKFKQQKYEINVLRNRINDNQKVSKTR 272
E K + + K K++K E R R +K + R
Sbjct: 151 KERGKRERKRK-KRKKEEREKKRERNRKERKKERER 185
Score = 41.6 bits (96), Expect = 8e-04
Identities = 36/146 (24%), Positives = 70/146 (47%), Gaps = 9/146 (6%)
Query: 137 NEREKERQNRLAEERARREEEENRRKAEDEARKKKALSNMMHFGGYIQKAQTERKSGKRQ 196
+ER+KER+ R E+R R E+E +R+ + +KK+ +K + +++ +R+
Sbjct: 34 SERKKERRER--EKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERRE 91
Query: 197 TEREKKKKILAERRKVLAIDHLNEDQLREKAKELWQSIYNLEAEKFDLQEKFKQQKYEIN 256
ER K+KK +R + + RE+ K+ + E ++ +++ K++K +
Sbjct: 92 KERRKRKKEKKKRER-------KQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRR 144
Query: 257 VLRNRINDNQKVSKTRGKAKVTGRWK 282
R R + K + R K K R K
Sbjct: 145 KERKREKERGKRERKRKKRKKEEREK 170
Score = 37.4 bits (85), Expect = 0.015
Identities = 32/147 (21%), Positives = 66/147 (44%), Gaps = 3/147 (2%)
Query: 134 RIRNEREKERQNRLAEERARREEEENRRKAEDEARKKKALSNMMHFGGYIQKAQTERKSG 193
++ E + + +++ +RE E + + E E RK++ G +K + +RK
Sbjct: 12 KLNTELQMVSCSHISKPCTQRESERKKERREREKRKREREKERKRERG--KKEKKKRKKR 69
Query: 194 KRQTEREKKKKILAERRKVLAIDHLNEDQLREKAKELWQSIYNLEAEKFDLQEKFKQQKY 253
+R ERE+K+K ++RK + + +K +E Q +K + +E+ ++ K
Sbjct: 70 ERGKERERKRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQ 129
Query: 254 EINVLRNRINDNQKVSKTRGKAKVTGR 280
R + +K K R + K G+
Sbjct: 130 RRERKRKK-RRKKKRRKERKREKERGK 155
>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
Length = 793
Score = 72.4 bits (176), Expect = 4e-13
Identities = 63/284 (22%), Positives = 129/284 (45%), Gaps = 19/284 (6%)
Query: 3 DIEEVVEEYEEEEQEEQEEAAEEDAEAEAETE---ETRAEEDEEEEEAKEAEDGPMEESK 59
D EE +E ++E++EE+EE + + E + E E + E +EE ++G + +
Sbjct: 179 DAEENKKE-DKEKEEEEEEKPKRGSIGENQVEVMVEEKTTESQEETVVMSLKNGQISSEE 237
Query: 60 PKPRSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHFENRKKEEEELVSLK 119
PK +I E+++ +D R E+ E + E KK +E ++
Sbjct: 238 PKQEEEREQ-GSDEISHHEKMEEEDKERAEAERARLEAEERERIKAEQDKKIADERARIE 296
Query: 120 DRIERRRAERAEQQRIRNEREKERQNRLAEERARREEEENRRKAEDEAR----KKKALSN 175
+ ER ++ ER +E + R AEER R +EEE +R AE+ R +K+A
Sbjct: 297 AEEKAAAQERERREAEERERMREEEKRAAEERQRIKEEE-KRAAEERQRIKEEEKRAAEE 355
Query: 176 MMHFGGYIQKAQTERKSG------KRQTEREKKKKILAERRKVLAIDHLNEDQLREKAKE 229
++A ER+ K + E +K+ K L E++ + + +++ +K +
Sbjct: 356 RQRIKEEEKRAAEERQRARAEEEEKAKVEEQKRNKQLEEKKHAMQETKIKGEKVEQKIEG 415
Query: 230 LWQSIYNLEAEKFD---LQEKFKQQKYEINVLRNRINDNQKVSK 270
W + + +K L+++ +++ ++ R ++ +++ K
Sbjct: 416 KWVNEKKAQEDKLQTAVLKKQGEEKGTKVQAKREKLQEDKPTFK 459
Score = 70.9 bits (172), Expect = 1e-12
Identities = 66/288 (22%), Positives = 126/288 (43%), Gaps = 43/288 (14%)
Query: 9 EEYEEEEQEEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDGPMEES-----KPKPR 63
E YE EE E ++ +++ +AE + +E EEEEE K E + K
Sbjct: 158 ERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQVEVMVEEKTT 217
Query: 64 SFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHFENRKKEEEELVSLKDRIE 123
V + +G+ + + E+ +E+ +H E ++E++E + E
Sbjct: 218 ESQEETVVMSLKNGQISSEEPKQEEEREQGSDEI-----SHHEKMEEEDKE----RAEAE 268
Query: 124 RRRAERAEQQRIRNEREKE----------RQNRLAEERARREEEENRRKAEDEARKKKAL 173
R R E E++RI+ E++K+ + A+ER RRE EE R E+E R +
Sbjct: 269 RARLEAEERERIKAEQDKKIADERARIEAEEKAAAQERERREAEERERMREEEKRAAEER 328
Query: 174 SNMMHFGGYIQKAQTERKSGKRQTEREKKKKILAERRKVLAIDHLNEDQLREKAKELWQS 233
+ K + +R + +RQ +E++K+ ER+++ + ++A E Q
Sbjct: 329 QRI--------KEEEKRAAEERQRIKEEEKRAAEERQRI--------KEEEKRAAEERQR 372
Query: 234 IYNLEAEKFDLQEKFKQQKYEINVLRNRINDNQKVSKTRGKAKVTGRW 281
E EK ++E+ + ++ E + K+ + + K+ G+W
Sbjct: 373 ARAEEEEKAKVEEQKRNKQLE---EKKHAMQETKIKGEKVEQKIEGKW 417
Score = 52.8 bits (125), Expect = 3e-07
Identities = 45/173 (26%), Positives = 86/173 (49%), Gaps = 18/173 (10%)
Query: 5 EEVVEEYEEEEQEEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDGPMEESKPKPRS 64
EE+ +E ++++E +EE + TE + + K E+ S+P R+
Sbjct: 461 EEIKDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQNGEFMTHKLKHTEN---TFSRPGGRA 517
Query: 65 FMPNLVP---PKIPDGERVDFDDIHRKRMEKDLNELQALIEAHFENRKKEEE---ELVSL 118
+ P++ G+R++ ++ R+R E + E + L ++K++E EL L
Sbjct: 518 SVDTKEAEGAPQVEAGKRLE--ELRRRRGETESEEFEKL-------KQKQQEAALELEEL 568
Query: 119 KDRIERRRAERAEQQRIRNEREKERQNRLAEERARREEEENRRKAEDEARKKK 171
K + E RR E+++ R + E +R+ R EE+ R +EE RR+AE +++K
Sbjct: 569 KKKREERRKVLEEEEQRRKQEEADRKLREEEEKRRLKEEIERRRAEAAEKRQK 621
Score = 45.8 bits (107), Expect = 4e-05
Identities = 52/241 (21%), Positives = 98/241 (40%), Gaps = 40/241 (16%)
Query: 4 IEEVVEEYEEEEQEEQEEAAE--------EDAEAEAETEETRAEEDE---EEEEAKEAED 52
+E+ +E E++ QE+ + E+ + + + + +ED+ ++EE K+ +
Sbjct: 409 VEQKIEGKWVNEKKAQEDKLQTAVLKKQGEEKGTKVQAKREKLQEDKPTFKKEEIKDEKI 468
Query: 53 GPMEESKPKPRSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHFENRKKEE 112
+E K + +SFM + +F K E + A + ++ E
Sbjct: 469 KKDKEPKEEVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPGG--RASVDTKEAEG 526
Query: 113 EELVSLKDRIERRRAERAEQQRIRNEREKERQNRLA-----------EERARREEEENRR 161
V R+E R R E + E+ K++Q A E R EEEE RR
Sbjct: 527 APQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRR 586
Query: 162 KAEDEARKKKALSNMMHFGGYIQKAQTERKSGKRQTEREKKKKILAERRKVLAIDHLNED 221
K E+ R K + E + + + E E+++ AE+R+ + D L++D
Sbjct: 587 KQEEADR----------------KLREEEEKRRLKEEIERRRAEAAEKRQKMPEDGLSDD 630
Query: 222 Q 222
+
Sbjct: 631 K 631
Score = 44.3 bits (103), Expect = 1e-04
Identities = 55/283 (19%), Positives = 111/283 (39%), Gaps = 34/283 (12%)
Query: 11 YEEEEQEEQEEAAEEDAEAEAETEETRAEEDE-----EEEEAKEAEDGPMEESKPKPRSF 65
Y+ + +E+E A E A E + EE+ ++ E P EE+K +
Sbjct: 27 YQRNDDDEEEAARERRRRARQERLRQKQEEESLGQVTDQVEVNAQNSVPDEEAKTTTTN- 85
Query: 66 MPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHFENRKKEEEELVSL------K 119
++ + F + +R E+ LQ +E E + +SL
Sbjct: 86 ------TQVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQN 139
Query: 120 DRIERRRAERAEQQRIRNER----EKERQNRLAEERARREEEENRR----KAEDEARKKK 171
D E E+ E+ R ER E E + ++ R+ EEN++ K E+E K K
Sbjct: 140 DTAENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPK 199
Query: 172 ALSNMMHFGGYIQKAQTERKSGKRQTEREKKKKILAERRKVLAIDHLNEDQLREKAKELW 231
G I + Q E ++ TE +++ +++ + ++ + +++ RE+ +
Sbjct: 200 R--------GSIGENQVEVMVEEKTTESQEETVVMSLKNGQISSEEPKQEEEREQGSDEI 251
Query: 232 QSIYNLEAEKFDLQEKFKQQKYEINVLRNRINDNQKVSKTRGK 274
+E E + E + + R + ++K++ R +
Sbjct: 252 SHHEKMEEEDKERAEAERARLEAEERERIKAEQDKKIADERAR 294
Score = 41.6 bits (96), Expect = 8e-04
Identities = 50/254 (19%), Positives = 96/254 (37%), Gaps = 52/254 (20%)
Query: 14 EEQEEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDGPMEESKPKPRSFMPNLVPPK 73
E + E E+ EAE + +D+EEE A+E
Sbjct: 5 ERRRELRRQKREEMRLEAERIAYQRNDDDEEEAARERR---------------------- 42
Query: 74 IPDGERVDFDDIHRKRMEKDLNELQALIEAHFENRKKEEEELVSLKDRIERRRAERAEQQ 133
R + + +K+ E+ L ++ +E + +N +EE A+
Sbjct: 43 ----RRARQERLRQKQEEESLGQVTDQVEVNAQNSVPDEE----------------AKTT 82
Query: 134 RIRNEREKERQNRLAEERARREEEENRRKAEDEARKKKALSNMMHFGGYIQKAQTERKSG 193
+ E + + E ARREE +R E R+K+ + + + + +
Sbjct: 83 TTNTQVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTA 142
Query: 194 KRQ-TEREKKKKILAERRKVLAIDHLNEDQLREKAKELWQSIYNLEAEKFDLQEKFKQQK 252
+ + TE+E+K + ER ++ E + K W+ +AE+ ++K K+++
Sbjct: 143 ENETTEKEEKSESRQERYEI----EETETVTKSYQKNDWR-----DAEENKKEDKEKEEE 193
Query: 253 YEINVLRNRINDNQ 266
E R I +NQ
Sbjct: 194 EEEKPKRGSIGENQ 207
Score = 38.5 bits (88), Expect = 0.007
Identities = 38/176 (21%), Positives = 76/176 (43%), Gaps = 16/176 (9%)
Query: 102 EAHFENRKKEEEELVSLKDRIERRRAERAEQQRIRNEREKERQNRLAEERARREEEENRR 161
E E R+++ EE+ +RI +R + E++ R R + RQ RL + ++EEE+
Sbjct: 5 ERRRELRRQKREEMRLEAERIAYQRNDDDEEEAARERRRRARQERLRQ----KQEEESLG 60
Query: 162 KAEDEA----------RKKKALSNMMHFGGYIQKAQTERKSGKRQTEREKKKKILAERRK 211
+ D+ + K + G + A ER + +R+ R+K+ + ER+K
Sbjct: 61 QVTDQVEVNAQNSVPDEEAKTTTTNTQVEGDDEAAFLERLA-RREERRQKRLQEALERQK 119
Query: 212 VLAIDHLNEDQLREKAKELWQSIYNLEAEKFDLQEKFKQQKYEINVLRNRINDNQK 267
+ + L ++ + E + + + + +Q++YEI QK
Sbjct: 120 EFD-PTITDASLSLPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQK 174
Score = 34.7 bits (78), Expect = 0.097
Identities = 32/121 (26%), Positives = 59/121 (48%), Gaps = 15/121 (12%)
Query: 3 DIEEVVEEYEE-----EEQEEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEAE------ 51
++EE+ ++ EE EE+E++ + E D + E E+ R +E+ E A+ AE
Sbjct: 564 ELEELKKKREERRKVLEEEEQRRKQEEADRKLREEEEKRRLKEEIERRRAEAAEKRQKMP 623
Query: 52 -DGPMEESKPKPRSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHFENRKK 110
DG ++ KP + F P KI ER +F + ++ + QA I + ++R +
Sbjct: 624 EDGLSDDKKPF-KCFTPKGSSLKIE--ERAEFLNKSVQKSSGVKSTHQAAIVSKIDSRLE 680
Query: 111 E 111
+
Sbjct: 681 Q 681
>gi|55741709 RNA binding motif protein 25 [Homo sapiens]
Length = 843
Score = 72.0 bits (175), Expect = 5e-13
Identities = 69/267 (25%), Positives = 122/267 (45%), Gaps = 15/267 (5%)
Query: 4 IEEVVEEYEEEEQEEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDGPMEESKPKPR 63
+EE + E+E QE ++E E + E E E E E + E E +E E E + + R
Sbjct: 291 LEEEKGKKEKERQEIEKERRERERERERERERREREREREREREREKEK---ERERERER 347
Query: 64 SFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHFENRKKEEEELVSLKDRIE 123
+ + D +R D R+R D N+ ++ +R++E E + E
Sbjct: 348 DRDRDRTKERDRDRDRERDRDRDRER-SSDRNKDRSRSREKSRDRERERERERERERERE 406
Query: 124 RRRAERAEQQRIRNEREKERQNRLAEERARREEEEN---RRKAEDEARKKKALSNMMHFG 180
R R E++R R ERE+ER+ ++R R E+EE+ RRK E + R+K+A
Sbjct: 407 RERERERERERER-EREREREK--DKKRDREEDEEDAYERRKLERKLREKEAAYQERLKN 463
Query: 181 GYIQKAQTERKSGKRQTEREKKKKILAERRKVLA-----IDHLNEDQLREKAKELWQSIY 235
I++ + R+ K E++++ +A+ K L D +D + L + +
Sbjct: 464 WEIRERKKTREYEKEAEREEERRREMAKEAKRLKEFLEDYDDDRDDPKYYRGSALQKRLR 523
Query: 236 NLEAEKFDLQEKFKQQKYEINVLRNRI 262
+ E E + K++K E+ +R R+
Sbjct: 524 DREKEMEADERDRKREKEELEEIRQRL 550
Score = 63.2 bits (152), Expect = 3e-10
Identities = 68/294 (23%), Positives = 125/294 (42%), Gaps = 42/294 (14%)
Query: 6 EVVEEYEEEEQEEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDGPMEESKPKPRSF 65
E V +EE +E+ + ++ + E R E ++E++ P ++ K K
Sbjct: 186 ETVTNDDEEALDEETKRRDQMIKGAIEVL-IREYSSELNAPSQESDSHPRKKKKEKKEDI 244
Query: 66 MPNL-VPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHF---------ENRKKEEEEL 115
V P IP + +DI+ ME+D +L + + F E KKE+E
Sbjct: 245 FRRFPVAPLIPY-PLITKEDINAIEMEEDKRDLISREISKFRDTHKKLEEEKGKKEKERQ 303
Query: 116 VSLKDRIERRRAERAEQQRIRNEREKERQNRLAEERARREEEE---------------NR 160
K+R ER R E++R ERE+ER+ +E+ R E E +R
Sbjct: 304 EIEKERRERERERERERERREREREREREREREKEKERERERERDRDRDRTKERDRDRDR 363
Query: 161 RKAEDEARKKKALSNMMHFGGYIQKAQTERKSGKRQTEREKKKKILAERRKVLAIDHLNE 220
+ D R++ + N ++++ KS R+ ERE++++ ER + + E
Sbjct: 364 ERDRDRDRERSSDRNK-------DRSRSREKSRDRERERERERERERERERERERERERE 416
Query: 221 DQLREKAKELWQSIYNLEAEKFDLQEKFKQQKYEINVLRNRINDNQKVSKTRGK 274
+ RE+ +E E +K +E+ ++ YE L ++ + + + R K
Sbjct: 417 RE-RERERE-------REKDKKRDREEDEEDAYERRKLERKLREKEAAYQERLK 462
Score = 61.2 bits (147), Expect = 1e-09
Identities = 45/167 (26%), Positives = 82/167 (49%), Gaps = 9/167 (5%)
Query: 3 DIEEVVEEYEEEEQEEQEEAAEEDAEAEAETEETR-AEEDEEEEEAKEAEDGPMEESKPK 61
D E+ E + E + ++EAA ++ E E + E E+E E +E M + +
Sbjct: 436 DEEDAYERRKLERKLREKEAAYQERLKNWEIRERKKTREYEKEAEREEERRREMAKEAKR 495
Query: 62 PRSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHFENRKKEEEELVSLKDR 121
+ F+ + D +R D ++K L + + +EA +RK+E+EEL ++ R
Sbjct: 496 LKEFLEDY------DDDRDDPKYYRGSALQKRLRDREKEMEADERDRKREKEELEEIRQR 549
Query: 122 I--ERRRAERAEQQRIRNEREKERQNRLAEERARREEEENRRKAEDE 166
+ E AE QR+ E E+ RQ ++ +E EEEE +++ E++
Sbjct: 550 LLAEGHPDPDAELQRMEQEAERRRQPQIKQEPESEEEEEEKQEKEEK 596
Score = 60.5 bits (145), Expect = 2e-09
Identities = 49/220 (22%), Positives = 100/220 (45%), Gaps = 27/220 (12%)
Query: 10 EYEEEEQEEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDGPMEESK------PKPR 63
E E E + E+E E + E E E E R E +++ + +E E+ E K K
Sbjct: 396 EREREREREREREREREREREREREREREREKDKKRDREEDEEDAYERRKLERKLREKEA 455
Query: 64 SFMPNLVPPKIPDGERV-------DFDDIHRKRMEKDLNELQALIEAHFENRKKEEEELV 116
++ L +I + ++ + ++ R+ M K+ L+ +E + ++R +
Sbjct: 456 AYQERLKNWEIRERKKTREYEKEAEREEERRREMAKEAKRLKEFLEDYDDDRDDPKYYRG 515
Query: 117 S-----LKDRIERRRAERAEQQRIRNEREKERQNRLAEERARREEEENRRKAEDEARKKK 171
S L+DR + A+ +++R + E E+ RQ LAE + E R + E E R++
Sbjct: 516 SALQKRLRDREKEMEADERDRKREKEELEEIRQRLLAEGHPDPDAELQRMEQEAERRRQP 575
Query: 172 ALSNMMHFGGYIQKAQTERKSGKRQTEREKKKKILAERRK 211
+ Q+ ++E + ++Q + EK+++ + E +
Sbjct: 576 QIK---------QEPESEEEEEEKQEKEEKREEPMEEEEE 606
Score = 56.6 bits (135), Expect = 2e-08
Identities = 43/152 (28%), Positives = 79/152 (51%), Gaps = 7/152 (4%)
Query: 9 EEYEEEEQEEQEEAAEEDAEAEAETEETRAEEDEEEEEAKE-AEDGPMEESKPKPRSFMP 67
E + E E+++ E + EAE E EE R E +E + KE ED ++ + P+ +
Sbjct: 459 ERLKNWEIRERKKTREYEKEAERE-EERRREMAKEAKRLKEFLED--YDDDRDDPKYYRG 515
Query: 68 NLVPPKIPDGER-VDFDDIHRKRMEKDLNELQALIEAHFENRKKEEEELVSLKDRIERRR 126
+ + ++ D E+ ++ D+ RKR +++L E++ + A E + EL ++ ERRR
Sbjct: 516 SALQKRLRDREKEMEADERDRKREKEELEEIRQRLLA--EGHPDPDAELQRMEQEAERRR 573
Query: 127 AERAEQQRIRNEREKERQNRLAEERARREEEE 158
+ +Q+ E E+E+Q + + EEEE
Sbjct: 574 QPQIKQEPESEEEEEEKQEKEEKREEPMEEEE 605
Score = 35.0 bits (79), Expect = 0.074
Identities = 23/70 (32%), Positives = 37/70 (52%), Gaps = 5/70 (7%)
Query: 2 SDIEEVVEEYEEEEQEE--QEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDGPMEESK 59
++++ + +E E Q + QE +EE+ E + E EE R E EEEE E E P +
Sbjct: 560 AELQRMEQEAERRRQPQIKQEPESEEEEEEKQEKEEKREEPMEEEE---EPEQKPCLKPT 616
Query: 60 PKPRSFMPNL 69
+P S P++
Sbjct: 617 LRPISSAPSV 626
Score = 34.7 bits (78), Expect = 0.097
Identities = 17/60 (28%), Positives = 35/60 (58%), Gaps = 1/60 (1%)
Query: 3 DIEEVVEEYEEEEQEEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDGPMEESKPKP 62
D + ++ E+E + ++ +++ E+E E EE + E++E+ EE E E+ P ++ KP
Sbjct: 557 DPDAELQRMEQEAERRRQPQIKQEPESE-EEEEEKQEKEEKREEPMEEEEEPEQKPCLKP 615
Score = 30.8 bits (68), Expect = 1.4
Identities = 17/59 (28%), Positives = 26/59 (44%)
Query: 13 EEEQEEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDGPMEESKPKPRSFMPNLVP 71
E ++ EQE + + E E EE+++E+E K E EE + P L P
Sbjct: 561 ELQRMEQEAERRRQPQIKQEPESEEEEEEKQEKEEKREEPMEEEEEPEQKPCLKPTLRP 619
Score = 28.1 bits (61), Expect = 9.0
Identities = 23/90 (25%), Positives = 36/90 (40%), Gaps = 19/90 (21%)
Query: 1 MSDIEEVVEEYEEEEQEEQEEAAE----------EDAEAEAETEETRAE---------ED 41
+ D E+ +E E + + E+EE E D +AE + E AE E
Sbjct: 522 LRDREKEMEADERDRKREKEELEEIRQRLLAEGHPDPDAELQRMEQEAERRRQPQIKQEP 581
Query: 42 EEEEEAKEAEDGPMEESKPKPRSFMPNLVP 71
E EEE +E ++ + +P P P
Sbjct: 582 ESEEEEEEKQEKEEKREEPMEEEEEPEQKP 611
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
sapiens]
Length = 570
Score = 72.0 bits (175), Expect = 5e-13
Identities = 62/277 (22%), Positives = 139/277 (50%), Gaps = 28/277 (10%)
Query: 5 EEVVEEYEEEEQEEQEEAAEEDAEAEAE-------TEETRAEED---EEEEEAKEAEDGP 54
EE ++E EE+ QE++E+ E++ + + E+ R +E+ E+EE+ +E E+
Sbjct: 294 EEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKM 353
Query: 55 MEESKPKPRSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHFENRKKEEEE 114
E+ K + + KI + E+ + R E+ + E + I E +++EE+
Sbjct: 354 HEQEKIREQE-EKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEK 412
Query: 115 LVSLKDRIERRRAERAEQ-QRIRNEREKERQNRLAEERARREEEENRRKAED--EARKKK 171
+ ++++ + E EQ +++R + EK R+ +E+ RE+EE R+ E+ + +++K
Sbjct: 413 MGEQEEKMWEQEEEMQEQEEKMRRQEEKIRE----QEKKIREQEEKIREQEEMMQEQEEK 468
Query: 172 ALSNMMHFGGYIQKAQTERKSGKRQTE--REKKKKILAERRKVLAIDHLNEDQLREKAKE 229
K Q + + +RQ E RE++KKI + K+ E+ ++E+ ++
Sbjct: 469 MGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKI----REQEEMMQEQEEK 524
Query: 230 LWQSIYNLEAEKFDLQEKFKQQKYEINVLRNRINDNQ 266
+W+ E + + +EK ++Q+ ++ ++ + +
Sbjct: 525 MWEQ----EEKMCEQEEKMQEQEEKMRRQEEKMREQE 557
Score = 59.7 bits (143), Expect = 3e-09
Identities = 50/230 (21%), Positives = 111/230 (48%), Gaps = 15/230 (6%)
Query: 3 DIEEVVEEYE-----EEEQEEQEEAAEEDAEAEAETEETRAEED--EEEEEAKEAEDGPM 55
++EE + E E EE+++E+E+ E++ E E + R EE E+EE+ +E E+ M
Sbjct: 348 ELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEE-MM 406
Query: 56 EESKPKPRSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHFENRKKEEEEL 115
+E + K M E + + +R E+ + E + I E +++EE +
Sbjct: 407 QEQEEK----MGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMM 462
Query: 116 VSLKDRIERRRAERAEQQRIRNEREKERQNRLAEERARREEEENRRKAEDEARKKKALSN 175
++++ + + EQ+ E+E++ + +E RE+E+ R+ E++ R+++ +
Sbjct: 463 QEQEEKMGEQEGKMCEQEAKMQEQEEKMRR---QEEKIREQEKKIREQEEKIREQEEMMQ 519
Query: 176 MMHFGGYIQKAQTERKSGKRQTEREKKKKILAERRKVLAIDHLNEDQLRE 225
+ Q+ + + K Q + EK ++ + R+ E++++E
Sbjct: 520 EQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMREQEVRLRQQEEKMQE 569
Score = 56.6 bits (135), Expect = 2e-08
Identities = 55/276 (19%), Positives = 122/276 (44%), Gaps = 37/276 (13%)
Query: 15 EQEEQEEAAEEDAEAEAETEETRAEEDEEE--EEAKEAEDGPM--EESKPKPRSFMPNLV 70
+Q+ Q EA E ++ + + +A+ +E E + ++ M +E K + R
Sbjct: 248 QQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQERE------ 301
Query: 71 PPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHFENRKKEEEELVSLKDRIERRRAERA 130
E++ + + E+ + + ++ E +++EE + +++I +
Sbjct: 302 -------EKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMH 354
Query: 131 EQQRIRNEREKERQNRLAEERARREEEE-----NRRKAEDEARKKKALSNMMH-----FG 180
EQ++IR + EK ++ E+ +R+E+E K ++ K + MM G
Sbjct: 355 EQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMG 414
Query: 181 GYIQK-------AQTERKSGKRQTE--REKKKKILAERRKVLAIDHLNEDQLREKAKELW 231
+K Q + + +RQ E RE++KKI + K+ + + ++Q EK E
Sbjct: 415 EQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQ-EEKMGEQE 473
Query: 232 QSIYNLEAEKFDLQEKFKQQKYEINVLRNRINDNQK 267
+ EA+ + +EK ++Q+ +I +I + ++
Sbjct: 474 GKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEE 509
Score = 49.3 bits (116), Expect = 4e-06
Identities = 33/147 (22%), Positives = 78/147 (53%), Gaps = 4/147 (2%)
Query: 1 MSDIEEVVEEYEEEEQEEQEEAAEEDAEAEAETEETRAEED--EEEEEAKEAEDGPM--E 56
M + EE ++E EE+ + ++E+ E++ + + E+ R +E+ +E+EE ++G M +
Sbjct: 420 MWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQ 479
Query: 57 ESKPKPRSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHFENRKKEEEELV 116
E+K + + KI + E+ + + R ++++ + Q E + E+EE +
Sbjct: 480 EAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKM 539
Query: 117 SLKDRIERRRAERAEQQRIRNEREKER 143
++ RR+ E+ +Q +R +++E+
Sbjct: 540 QEQEEKMRRQEEKMREQEVRLRQQEEK 566
Score = 35.0 bits (79), Expect = 0.074
Identities = 30/145 (20%), Positives = 71/145 (48%), Gaps = 14/145 (9%)
Query: 123 ERRRAERAEQQRIRNEREKERQN-------RLAEERARREEEENRRKAEDEARKK-KALS 174
+ ++A Q+ +R E E + Q + + A + ++ E EAR L
Sbjct: 97 DEQKASHQHQEALRRELEAQVQTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRLH 156
Query: 175 NMMHFGGYIQKAQTERKSGKRQTEREKKKKILAERRKVLAID----HLNEDQLREKAKEL 230
+ F G +++A + + K++ +R ++ L + R L+++ + +++L+EK +L
Sbjct: 157 DSWKFAGELEQALSAVATQKKKADRYIEE--LTKERDALSLELYRNTITDEELKEKNAKL 214
Query: 231 WQSIYNLEAEKFDLQEKFKQQKYEI 255
+ + +E+EK ++Q K+ K ++
Sbjct: 215 QEKLQLVESEKSEIQLNVKELKRKL 239
>gi|50726968 microfibrillar-associated protein 1 [Homo sapiens]
Length = 439
Score = 71.6 bits (174), Expect = 7e-13
Identities = 73/294 (24%), Positives = 137/294 (46%), Gaps = 35/294 (11%)
Query: 1 MSDIEEVVEEYE----EEEQEEQEEAAEEDAEAEAETE--ETRAEEDEEEEEAK-----E 49
M +E EE++ +EQE + E EED+ ++ + R ED EE A+ E
Sbjct: 50 MESSDEEDEEFQFIKKAKEQEAEPEEQEEDSSSDPRLRRLQNRISEDVEERLARHRKIVE 109
Query: 50 AEDGPMEESKPKPRSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHFENRK 109
E +S+ + ++ + E +D ++I R+R ++ + RK
Sbjct: 110 PEVVGESDSEVEGDAWRMEREDSSEEEEEEIDDEEIERRR---------GMMRQRAQERK 160
Query: 110 KEEEELVSLKDRIERRRAERAEQQRIRNE---REKERQNRLAEERARREEEENRRKAEDE 166
EE E++ ++D E R E +E + E E E + RL R+++ ++ E E
Sbjct: 161 NEEMEVMEVED--EGRSGEESESESEYEEYTDSEDEMEPRLKPVFIRKKDRVTVQEREAE 218
Query: 167 ARKKKALSNMMHFGGYIQKAQTERKSGKRQTEREKKKKILAERRKVLAIDHLN-EDQLRE 225
A K+K L + A+ RK + E E KK++ +R + A+D LN +D+ E
Sbjct: 219 ALKQKELEQEAK-----RMAEERRKYTLKIVEEETKKELEENKRSLAALDALNTDDENDE 273
Query: 226 KAKELW--QSIYNLEAEKFDLQEKFKQQKYEINVLRNRINDNQKVSKTRGKAKV 277
+ E W + + ++ ++ D +E +++K EI +RN + + ++ ++ R KV
Sbjct: 274 EEYEAWKVRELKRIKRDRED-REALEKEKAEIERMRN-LTEEERRAELRANGKV 325
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 71.2 bits (173), Expect = 9e-13
Identities = 63/270 (23%), Positives = 136/270 (50%), Gaps = 34/270 (12%)
Query: 5 EEVVEEYEEEEQEEQEEAAEEDAEAEAETEETRAEED---EEEEEAKEAEDGPME-ESKP 60
EE ++E+EE+ QE++E+ E++ + + E+ R +E+ E+EE+ + E+ E E K
Sbjct: 306 EEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKM 365
Query: 61 KPRSFMPNLVPPKIPDGERVDFDDIHR-KRMEKDLNELQALIEAHFENRKKEEEELVSLK 119
+ + M K+ E + ++ + + +E+ ++E + + E E +++EEE++ +
Sbjct: 366 RRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQ--EEKRQEEEKIREQE 423
Query: 120 DRIERRRAERAEQQRIRNEREK--------ERQNRLAEERARREEEENRRKAEDEARKKK 171
R E+ ++++IR + EK RQ E+ + EEE R++ E+ R+++
Sbjct: 424 KRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEE 483
Query: 172 ALSNMMHFGGYIQKAQTERKSGKRQTE---------REKKKKILAERRKVLAIDHLNEDQ 222
+ +K + + ++Q E RE+++KI + K+ E++
Sbjct: 484 KIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWR----QEEK 539
Query: 223 LREKAKELWQSIYNLEAEKFDLQEKFKQQK 252
+RE+ +E+W+ E EK QEK +++
Sbjct: 540 IREQ-EEMWR-----EEEKMHEQEKIWEEE 563
Score = 65.9 bits (159), Expect = 4e-11
Identities = 61/277 (22%), Positives = 138/277 (49%), Gaps = 37/277 (13%)
Query: 3 DIEEVVEEYEEEEQEEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDGPMEESKPKP 62
++EE + E E+ ++E++ EE + + +E A+ +EE+ +E E+ E+ K
Sbjct: 395 ELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMW 454
Query: 63 RSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHFENRKKEEEELVSLKDRI 122
R KI + E++ ++ KR E++ Q E + E+EE+ K+++
Sbjct: 455 RQ------EEKIHEQEKIREEE---KRQEQEEMWRQ-------EEKIHEQEEIWRQKEKM 498
Query: 123 -ERRRAERAEQQRIRNEREKERQNRLAEERARREEEENRRKAEDEARKKKAL---SNMMH 178
E+ R +++++ + EK R+ +E RE+EE + E++ R+++ + MH
Sbjct: 499 HEQEEKIRKQEEKVWRQEEKIRE----QEEKIREQEEKMWRQEEKIREQEEMWREEEKMH 554
Query: 179 FGGYI---QKAQTERKSGKRQTE--REKKKKILAERRKVLAIDHLNEDQLREKAKELWQS 233
I +K Q + RQ E RE+++K+ + K+ E++ +E+ +++W+
Sbjct: 555 EQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKI----REQEEKRQEQEEKMWKQ 610
Query: 234 IYNLEAEKFDLQEKFKQQKYEINVLRNRINDNQKVSK 270
E + + +EK ++Q+ +I +I + +++++
Sbjct: 611 ----EEKIREQEEKIQEQEEKIREQEEKIREQEEMTQ 643
Score = 62.0 bits (149), Expect = 6e-10
Identities = 43/194 (22%), Positives = 104/194 (53%), Gaps = 8/194 (4%)
Query: 89 RMEKDLNELQALIEAHFENRKKEEEELVSLKDRIERRRA---ERAEQQRIRNER--EKER 143
R E+ + E + I+ E +++EE++ ++++ R+ E+ E+ R + E EKE
Sbjct: 304 RQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEE 363
Query: 144 QNRLAEERARREEEENRRKAE---DEARKKKALSNMMHFGGYIQKAQTERKSGKRQTERE 200
+ R EE +EE+ RR+ E ++ K + L MH I++ + +R+ ++ E+E
Sbjct: 364 KMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQE 423
Query: 201 KKKKILAERRKVLAIDHLNEDQLREKAKELWQSIYNLEAEKFDLQEKFKQQKYEINVLRN 260
K+++ A+ + E+++RE+ K++W+ + ++ +E+ +Q++ E+
Sbjct: 424 KRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEE 483
Query: 261 RINDNQKVSKTRGK 274
+I++ +++ + + K
Sbjct: 484 KIHEQEEIWRQKEK 497
Score = 61.2 bits (147), Expect = 1e-09
Identities = 59/286 (20%), Positives = 133/286 (46%), Gaps = 22/286 (7%)
Query: 1 MSDIEEVVEEYEEEEQE----EQEEAAEEDAEAEAETEETRAEEDE----------EEEE 46
M + E++ E+ E+ ++E EQE+ E++A+ + E+ R +E++ +EE+
Sbjct: 400 MHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEK 459
Query: 47 AKEAEDGPMEESKPKPRSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHFE 106
E E EE + + KI + E + E+ + + + + E
Sbjct: 460 IHEQEKIREEEKRQEQEEMWRQ--EEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEE 517
Query: 107 NRKKEEEELVSLKDRIERRRAERAEQQRIRNEREK-ERQNRLAEERARREEEENRRKAED 165
+++EE++ ++++ R+ + EQ+ + E EK Q ++ EE R+E+E+ + E+
Sbjct: 518 KIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEE 577
Query: 166 EAR--KKKALSNMMHFGGYIQKAQTERKSGKRQTE--REKKKKILAERRKVLAIDHLNED 221
+ R ++K +K Q + + +Q E RE+++KI + K+ + +
Sbjct: 578 KIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIRE 637
Query: 222 QLREKAKELWQSIYNLEAEKFDLQEKFKQQKYEINVLRNRINDNQK 267
Q E +E + + E + + +EK ++Q+ + +I + +K
Sbjct: 638 Q-EEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEK 682
Score = 52.8 bits (125), Expect = 3e-07
Identities = 40/217 (18%), Positives = 101/217 (46%), Gaps = 19/217 (8%)
Query: 1 MSDIEEVVEEYEEEEQEEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDGPMEESKP 60
M + E++ EE + +EQE++ EE + E + E+ E+EE ++ ++ M + +
Sbjct: 553 MHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEE 612
Query: 61 KPRSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHFENRKKEEEELVSLKD 120
K R E++ + + E+ + E + + + E ++EE++ ++
Sbjct: 613 KIRE-----------QEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEE 661
Query: 121 RIERRRAERAEQQRIRNEREKERQNRLAEERARREEEENRRKAEDEARKKKALSNMMHFG 180
+++ + Q+ RE+E++ R EE+ R +EE + + E +++ +
Sbjct: 662 KMQEQEETMWRQE--EKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQE--- 716
Query: 181 GYIQKAQTERKSGKRQTEREKKKKILAERRKVLAIDH 217
+K Q + + +RQ E+ ++++ +++ +H
Sbjct: 717 ---EKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEH 750
>gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo
sapiens]
Length = 600
Score = 70.5 bits (171), Expect = 2e-12
Identities = 60/273 (21%), Positives = 115/273 (42%), Gaps = 7/273 (2%)
Query: 9 EEYEEEEQEEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDGPMEESKPKPRSFMPN 68
+E E E++ ++E ED +E E R E E E E K D + + R
Sbjct: 186 QERRERERQREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQ 245
Query: 69 LVPPKIPDGERVDFDDIHRKR-MEKDLNELQALIEAHFENRKKEEEELVSLKDRIERRRA 127
+ + E + R+R ++D + Q E + +++ E +DR R+
Sbjct: 246 AERERASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTE----RDRETERKR 301
Query: 128 ERAEQQRIRNEREKERQNRLAEERARREEEENRRKAEDEARKKKALSNMMHFGGYIQKAQ 187
ER ++ ER ++R+ ER R + E R E E +K+ M Q +
Sbjct: 302 ERQRERERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGR 361
Query: 188 TERKSGKRQTEREKKKKILAERRKVLAIDHLNEDQLREKAKELWQSIYNLEAEKFDLQEK 247
R+ +R+ ERE+++ + R + + D+ +E+ ++ + + + E +E+
Sbjct: 362 EGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQT-EKDRDGQRETEKQRER 420
Query: 248 FKQQKYEINVLRNRINDNQKVSKTRGKAKVTGR 280
K ++ E R R + QK + R + + T R
Sbjct: 421 EKDRESERGRERGREREKQK-GRERDRERQTDR 452
Score = 68.2 bits (165), Expect = 8e-12
Identities = 60/261 (22%), Positives = 118/261 (45%), Gaps = 13/261 (4%)
Query: 10 EYEEEEQEEQEEAAEEDAEAEAETEETRAEEDEEE---EEAKEAEDGPMEESKPKPRSFM 66
E E + E+E + D E + +TE R +E E E +E +E E +E+K + R
Sbjct: 148 ERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDR--- 204
Query: 67 PNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHFENRKKEEEELVSLKDRIERRR 126
+ + + ER + RKR + Q E E + + E +R + R
Sbjct: 205 -HSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERE 263
Query: 127 AERAEQQRIRNEREKERQNRLAEERARREEEENRRKAEDEARKKKALSNMMHFGGYIQKA 186
ER ++ R R+ R+KER+ + +R RR E + + + E ++++ + ++
Sbjct: 264 RER-DRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERE 322
Query: 187 QTERKSGKRQTEREKKKKILAERRKVLAIDHLNEDQLREKAKELWQSIYNLEAEKFDLQE 246
+ + +R+TER+++K+ +R++ +D Q + + + E E+ D Q
Sbjct: 323 RERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERER-DRQS 381
Query: 247 KFKQQKYEINVLRNRINDNQK 267
++++ E R+R D QK
Sbjct: 382 AREREERE----RDRDRDRQK 398
Score = 60.5 bits (145), Expect = 2e-09
Identities = 56/258 (21%), Positives = 118/258 (45%), Gaps = 19/258 (7%)
Query: 9 EEYEEEEQEEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDGPMEESKPKPRSFMPN 68
+ E+E+ Q+E E + E E E R + + E E + + E + R
Sbjct: 114 DRQREKERNRQKE-RERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTE 172
Query: 69 LVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHFENRKKEEEELVSLKDRIERRRAE 128
K + E+ + R+R + N+ + + H E ++ E E + + +R+ +
Sbjct: 173 RNRQKEREREKNRQERRERERQREKENKTE---DRHSERGRERERERETETETERKRQTD 229
Query: 129 RAEQQRIRNEREKERQ---NRLAEERARREEEENRRKAEDEARKKKALSNMMHFGGYIQK 185
R ++ + ERE+E+Q R +E R++E R + D R ++ ++
Sbjct: 230 RERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKE---------RE 280
Query: 186 AQTERKSGKRQTEREKKKKILAERRKVLAID-HLNEDQLREKAKELWQSIY-NLEAEKFD 243
QT+RK +R+TER+++ + ER++ + N + RE+ +E + E ++
Sbjct: 281 RQTDRKR-QRRTERDRETERKRERQRERERERERNRKRERERERERERERQRETERDREK 339
Query: 244 LQEKFKQQKYEINVLRNR 261
+E+ ++++ E++ RNR
Sbjct: 340 ERERKRKRQTEMDRERNR 357
Score = 57.8 bits (138), Expect = 1e-08
Identities = 56/258 (21%), Positives = 112/258 (43%), Gaps = 26/258 (10%)
Query: 12 EEEEQEEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDGPMEESKPKPRSFMPNLVP 71
E E ++E E+D + + R + E+E E + + + K + R
Sbjct: 72 ERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERET 131
Query: 72 PKIPDGERVDFDDIHRKRMEKDLNELQALIEAHFENRKKEEEELVSLKDRIERRRAERAE 131
+ + R D R+R E Q E E + E + + ++R + R E+
Sbjct: 132 EREGERGRDRQTDGQRER------ERQRDAEKERERQTDRERQRQTERNRQKEREREKNR 185
Query: 132 QQRIRNEREKERQNRLAEERARR-EEEENRRKAEDEARKKKALSNMMHFGGYIQKAQTER 190
Q+R ER++E++N+ + + R E E R+ E E +K+ QT+R
Sbjct: 186 QERRERERQREKENKTEDRHSERGRERERERETETETERKR---------------QTDR 230
Query: 191 -KSGKRQTEREKKKKILAERRKVLAIDHLNEDQLREKAKELWQSIYNLEAEKFDLQEKFK 249
+ +R+TERE++K+ AER + + D+ RE+ ++ + + E+ ++ +
Sbjct: 231 ERDRQRKTEREREKQ--AERERA-SERETERDKERERERDRDRDRDRRQKERERQTDRKR 287
Query: 250 QQKYEINVLRNRINDNQK 267
Q++ E + R + Q+
Sbjct: 288 QRRTERDRETERKRERQR 305
Score = 56.2 bits (134), Expect = 3e-08
Identities = 53/262 (20%), Positives = 104/262 (39%), Gaps = 21/262 (8%)
Query: 16 QEEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDGPMEESKPKPRSFMPNLVPPKIP 75
QE A +A+ ++ +E E +E E + + R
Sbjct: 34 QESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRERR----------R 83
Query: 76 DGERVDFDDIHRKRMEKDLNELQALIEAHFENRKKEEEELVSLKDRIERRRAERAEQQRI 135
+ +R D HR+R E + + + ++++E ++R R ER ++
Sbjct: 84 EKDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQT 143
Query: 136 RNEREKERQNRLAEERARREEEENRRKAE-----DEARKKKALSNMMHFGGYIQKAQTER 190
+RE+ERQ +ER R+ + E +R+ E + R+K ++ +TE
Sbjct: 144 DGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTED 203
Query: 191 KSGKRQTEREKKKKILAERRKVLAIDHLNEDQLREKAKELWQSIYNLEAEKFDLQEKFKQ 250
+ +R ERE++++ E + D D+ R+ +E +AE+ E+ +
Sbjct: 204 RHSERGRERERERETETETERKRQTDR-ERDRQRKTERE-----REKQAERERASERETE 257
Query: 251 QKYEINVLRNRINDNQKVSKTR 272
+ E R+R D + K R
Sbjct: 258 RDKERERERDRDRDRDRRQKER 279
Score = 56.2 bits (134), Expect = 3e-08
Identities = 44/203 (21%), Positives = 84/203 (41%), Gaps = 19/203 (9%)
Query: 9 EEYEEEEQEEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDGPMEESKPKPRSFMPN 68
+E E + +++ E D E E + E R E E E K + E + + R
Sbjct: 277 KERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQR----- 331
Query: 69 LVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHFENRKKEEEELVSLKDRIERRRAE 128
+ ER + RKR + + + + E R++ E E ER R
Sbjct: 332 -------ETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERER-------ERERER 377
Query: 129 RAEQQRIRNEREKERQNRLAEERARREEEENRRKAEDEARKKKALSNMMHFGGYIQKAQT 188
+ R R ERE++R +ER R+ E++ + E E ++++ G + +
Sbjct: 378 DRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQREREKDRESERGRERGRERE 437
Query: 189 ERKSGKRQTEREKKKKILAERRK 211
++K +R ER+ ++ +R++
Sbjct: 438 KQKGRERDRERQTDRQAGRQRKR 460
Score = 49.3 bits (116), Expect = 4e-06
Identities = 45/190 (23%), Positives = 77/190 (40%), Gaps = 18/190 (9%)
Query: 10 EYEEEEQEEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDGPMEESKPKPRSFMPNL 69
E E E ++E E + E E + E R E E E + K + E ++ R
Sbjct: 308 ERERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQA 367
Query: 70 VPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHFENRKKEEEELVSLKDRIERRRAER 129
+ + ER R+ E+D + +R+KE E KDR +R E+
Sbjct: 368 ERERERERERDRQSAREREERERDRDR----------DRQKERERQTE-KDRDGQRETEK 416
Query: 130 AEQQRIRNEREKERQNRLAEERAR-REEEENRRKAEDEARKKKALSNMMHFGGYIQKAQT 188
+ EREK+R++ ER R RE+++ R + + ++A Y+
Sbjct: 417 ------QREREKDRESERGRERGREREKQKGRERDRERQTDRQAGRQRKRSTLYVNPPPR 470
Query: 189 ERKSGKRQTE 198
+SG Q++
Sbjct: 471 TARSGVVQSD 480
Score = 41.2 bits (95), Expect = 0.001
Identities = 41/164 (25%), Positives = 74/164 (45%), Gaps = 12/164 (7%)
Query: 127 AERAEQQRIRN-EREKERQNRLAEERARREEEENRRKAEDEARKKKALSNMMHFGGYIQK 185
A+ +++R R ERE+ R+ R E R+ E RR+ +D RK+ ++
Sbjct: 49 ADGDDRERNRQKERERRREKRQTERETDRKRE--RRREKDRHRKRDRHRERQRDREKERE 106
Query: 186 AQTER-------KSGKRQTEREKKKKILAERRKVLAIDHLNEDQLREKAKELWQSIYNLE 238
QT+R K RQ ERE++ + ER + D E + + A++ + + E
Sbjct: 107 RQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRE 166
Query: 239 AEKFDLQEKFKQQKYEIN--VLRNRINDNQKVSKTRGKAKVTGR 280
++ + + K+++ E N R R +K +KT + GR
Sbjct: 167 RQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGR 210
Score = 35.4 bits (80), Expect = 0.057
Identities = 17/59 (28%), Positives = 29/59 (49%)
Query: 5 EEVVEEYEEEEQEEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDGPMEESKPKPR 63
EE + + + Q+E+E E+D + + ETE+ R E + E E E+ K + R
Sbjct: 386 EERERDRDRDRQKERERQTEKDRDGQRETEKQREREKDRESERGRERGREREKQKGRER 444
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 69.3 bits (168), Expect = 4e-12
Identities = 51/269 (18%), Positives = 135/269 (50%), Gaps = 34/269 (12%)
Query: 5 EEVVEEYEEEEQEEQEEAAEEDAEAEAETEETRAEEDE--EEEEAKEAEDGPMEESKPKP 62
EE ++E+EE+ QE++E+ E++ + + E+ R +E+ E+EE ++ M E + K
Sbjct: 306 EEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKM 365
Query: 63 RSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHFENRKKEEEELVSLKDRI 122
R + + E++ + +E+ ++E + + E + K++EEE K R
Sbjct: 366 RRLEEMMWEKE----EKI-------RELEEKMHEQEKIRE---QEEKRQEEE----KIRE 407
Query: 123 ERRRAERAEQQRIRNEREKERQNRLAEERARREEEENRRKAEDEARKKKALSNMMHFGGY 182
+ +R E+ + + E+ +E++ ++ E+ + +E + +++ R+++
Sbjct: 408 QEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQ 467
Query: 183 IQKAQTERKSGKRQTEREKKKKILAERRKVLAID---HLNEDQLREKAKELWQSIYNLEA 239
+K + + + +++ + +++KI + KV + H E+++RE+ +++W+
Sbjct: 468 EEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQ------ 521
Query: 240 EKFDLQEKFKQQKYEINVLRNRINDNQKV 268
+EK ++Q+ +I +I + +++
Sbjct: 522 -----EEKIREQEEKIREQEEKIREQEEM 545
Score = 68.6 bits (166), Expect = 6e-12
Identities = 61/274 (22%), Positives = 130/274 (47%), Gaps = 45/274 (16%)
Query: 1 MSDIEEVVEEYEEEEQEEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDGPMEESKP 60
M +EE++ E EE+ +E +E+ E++ E E E+ + EE E+E ++ ++ M +
Sbjct: 365 MRRLEEMMWEKEEKIRELEEKMHEQEKIREQE-EKRQEEEKIREQEKRQEQEAKMWRQEE 423
Query: 61 KPRSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHFENRKKE---EEELVS 117
K R E++ + R E+ ++E + + E ++E +EE +
Sbjct: 424 KIRE-----------QEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIR 472
Query: 118 LKDRIERRRAERAEQQRIRNEREK-----------ERQNRLAEERARREEE---ENRRKA 163
++ I R++ + EQ++IR + EK E + R EE+ R+EE E K
Sbjct: 473 EQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKI 532
Query: 164 EDEARKKKALSNMMHFGGYIQKAQTERKSGKRQTEREKKKKILAERRKVLAIDHL---NE 220
++ K + MM + E K G+++ + ++++K+ + K+ + +
Sbjct: 533 REQEEKIREQEEMMQ--------EQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQK 584
Query: 221 DQLREKAKELWQSIYNLEAEKFDLQEKFKQQKYE 254
+++RE+ +++W+ + EK QE+ Q++ E
Sbjct: 585 EKIREQEEKIWE-----QEEKIREQEEMMQEQEE 613
Score = 60.5 bits (145), Expect = 2e-09
Identities = 52/249 (20%), Positives = 115/249 (46%), Gaps = 25/249 (10%)
Query: 5 EEVVEEYE------EEEQEEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDGPMEES 58
EE + E E EE+ EQE+ EE+ E E + E+ E+EE ++ E+
Sbjct: 429 EEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQE 488
Query: 59 KPKPRSFMPNLVPPKIPDGE-RVDFDDIHRKRMEKDLNELQALIEAHFENRKKEEEELVS 117
K + + K+ D E ++ + R E+ + E + I E +++EE +
Sbjct: 489 KIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQE 548
Query: 118 LKDRIERRRAERAEQQRIRNEREKERQNRLAEERARREEEENRRKAEDEARKKKALSNMM 177
++++ + + EQ+++R + EK R+ EE+ R ++E+ R + E +++ +
Sbjct: 549 QEEKMGEQEEKMQEQEKMRRQEEKIREQ---EEKIREQKEKIREQEEKIWEQEEKI---- 601
Query: 178 HFGGYIQKAQTERKSGKRQTEREKKKKILAERRKVLAIDHLNEDQLREKAKELWQSIYNL 237
+ Q E + + E+++K+ + K+ E+++R + +++W+ L
Sbjct: 602 -------REQEEMMQEQEEKMWEQEEKMCEQEEKM----QEQEEKMRRQEEKMWEQEVRL 650
Query: 238 EAEKFDLQE 246
++ +QE
Sbjct: 651 RQQEEKMQE 659
Score = 53.1 bits (126), Expect = 3e-07
Identities = 59/309 (19%), Positives = 141/309 (45%), Gaps = 58/309 (18%)
Query: 4 IEEVVEEYEEEEQE------EQEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDGPMEE 57
IEE+ +E + E EE E++A+ + + + +E+ E + KE ++
Sbjct: 195 IEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKE-----LKR 249
Query: 58 SKPKPRSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHFENRK-------K 110
+ + +P +++ + H + K+L + A ++A E + +
Sbjct: 250 KLERAKLLLPQ---------QQLQAEADH---LGKELQSVSAKLQAQVEENELWNRLNQQ 297
Query: 111 EEEELVSLKDRIERRRAERAEQQ-RIRNEREKERQNRLAEERARREE------EENRRKA 163
+EE++ +++I+ + EQ+ +IR + EK R+ EE+ RR+E EE R+
Sbjct: 298 QEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQ---EEKMRRQEEMMWEKEEKMRRQ 354
Query: 164 E------------------DEARKKKALSNMMHFGGYIQKAQTERKSGKRQTEREKKKKI 205
E ++ K + L MH I++ + +R+ ++ E+EK+++
Sbjct: 355 EEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQ 414
Query: 206 LAERRKVLAIDHLNEDQLREKAKELWQSIYNLEAEKFDLQEKFKQQKYEINVLRNRINDN 265
A+ + E+++RE+ K++W+ + ++ +E+ +Q++ E+ +I +
Sbjct: 415 EAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQ 474
Query: 266 QKVSKTRGK 274
+++ + + K
Sbjct: 475 EEIWRQKEK 483
Score = 50.4 bits (119), Expect = 2e-06
Identities = 42/173 (24%), Positives = 82/173 (47%), Gaps = 20/173 (11%)
Query: 1 MSDIEEVVEEYEE------EEQEEQEEAAEEDAEAEAETEETRAEEDE----EEEEAKEA 50
M D EE + E EE E+ EQEE E E E EE E++E +EE+ +E
Sbjct: 504 MHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQ 563
Query: 51 EDGPMEESKPKPRSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHFENRKK 110
E +E K + + KI + E ++ E+ + E + +++ E +
Sbjct: 564 EKMRRQEEKIREQEEKIREQKEKIREQEEKIWE------QEEKIREQEEMMQEQEEKMWE 617
Query: 111 EEEELVSLKDRIERRRAERAEQQRIRNEREKERQNRLAEERARREEEENRRKA 163
+EE++ +++++ E+ E+ R + E+ E++ RL ++ + +E + +A
Sbjct: 618 QEEKMCEQEEKMQ----EQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLEA 666
>gi|102467235 inner centromere protein antigens 135/155kDa isoform 1
[Homo sapiens]
Length = 918
Score = 68.2 bits (165), Expect = 8e-12
Identities = 63/231 (27%), Positives = 113/231 (48%), Gaps = 44/231 (19%)
Query: 9 EEYEEEEQEEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDGPMEESKPKPRSFMPN 68
E E+ ++E++++ ++ A+ + +TE+ + E EE+ K+A MEE +
Sbjct: 586 ERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEA-------- 637
Query: 69 LVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHFENR------KKEEEELVSLKDRI 122
R++ E++ L+ L + E R KK+EEE L+
Sbjct: 638 ------------------RRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAA 679
Query: 123 ERRR-AERAEQQRIRNEREKERQNRLAEERARREE---EENRRKAEDEARKKKALSNMMH 178
E +R AE+ EQ+R RE+ER+ + E+ RRE+ E+ R+ AE E R+++ +
Sbjct: 680 EAKRLAEQREQER----REQERREQERREQERREQERREQERQLAEQERRREQ---ERLQ 732
Query: 179 FGGYIQKAQTERKSGKRQTEREKKKKILAERRKVLAIDHLNEDQLREKAKE 229
+Q+ + + K Q +RE ++K E ++ LA L E+Q +KAKE
Sbjct: 733 AERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQ-EKKAKE 782
Score = 61.2 bits (147), Expect = 1e-09
Identities = 61/245 (24%), Positives = 109/245 (44%), Gaps = 29/245 (11%)
Query: 32 ETEETRAEEDEEEEEAKEAEDGPMEESKPKPRSFMPNLVPPKIPDGERVDFDDIHRKRME 91
E E R E +EEA++ +EE K + L K+ ER+ R+R+E
Sbjct: 536 EKERQRLENLRRKEEAEQLRRQKVEEDKRR------RLEEVKLKREERLRKVLQARERVE 589
Query: 92 KDLNELQALIEAHFENRKKEEEELVSLKDRIERRRAERAEQQRIRNEREKERQNRLAEER 151
+ E + IE F ++ E K + ER E+A+++ + E+ R EE
Sbjct: 590 QMKEEKKKQIEQKFAQIDEKTE-----KAKEERLAEEKAKKKAAAKKMEEVEARRKQEEE 644
Query: 152 ARR-----EEEENRRKAEDEARKKKALSNMMHFGGYIQKAQTERKSGKRQTEREKKKKIL 206
ARR +EEE RR E +KK+ + ++ +R+ +R+ ER ++++
Sbjct: 645 ARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERRE 704
Query: 207 AERRKVLAIDHLNEDQLREKAKELWQSIYNLEAEKF----DLQEKFKQQKYEINVLRNRI 262
ERR E + RE+ ++L + E E+ +LQE+ K + + L+ +
Sbjct: 705 QERR---------EQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQREL 755
Query: 263 NDNQK 267
+ +K
Sbjct: 756 EEKKK 760
Score = 60.1 bits (144), Expect = 2e-09
Identities = 49/174 (28%), Positives = 84/174 (48%), Gaps = 47/174 (27%)
Query: 5 EEVVEEYEEEEQEEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDGPMEESKPKPRS 64
+E++++ +EEEQE +AAE AE + E+ R E++ E+E +E E E
Sbjct: 661 QELLQKKKEEEQERLRKAAEAKRLAE-QREQERREQERREQERREQERREQE-------- 711
Query: 65 FMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHFENRKKEEEELVSLKDRIER 124
R+ E+ L E + R++E+E L + ++ ER
Sbjct: 712 ----------------------RREQERQLAE---------QERRREQERLQAERELQER 740
Query: 125 RRAERAEQQRIRNERE----KERQNRLAEERARREEEENRRKAEDEARKKKALS 174
+A R ++++++ E E KE Q RLAE R+ +EE +KA++ A KAL+
Sbjct: 741 EKALRLQKEQLQRELEEKKKKEEQQRLAE---RQLQEEQEKKAKEAAGASKALN 791
>gi|102467242 inner centromere protein antigens 135/155kDa isoform 2
[Homo sapiens]
Length = 914
Score = 68.2 bits (165), Expect = 8e-12
Identities = 63/231 (27%), Positives = 113/231 (48%), Gaps = 44/231 (19%)
Query: 9 EEYEEEEQEEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDGPMEESKPKPRSFMPN 68
E E+ ++E++++ ++ A+ + +TE+ + E EE+ K+A MEE +
Sbjct: 582 ERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEA-------- 633
Query: 69 LVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHFENR------KKEEEELVSLKDRI 122
R++ E++ L+ L + E R KK+EEE L+
Sbjct: 634 ------------------RRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAA 675
Query: 123 ERRR-AERAEQQRIRNEREKERQNRLAEERARREE---EENRRKAEDEARKKKALSNMMH 178
E +R AE+ EQ+R RE+ER+ + E+ RRE+ E+ R+ AE E R+++ +
Sbjct: 676 EAKRLAEQREQER----REQERREQERREQERREQERREQERQLAEQERRREQ---ERLQ 728
Query: 179 FGGYIQKAQTERKSGKRQTEREKKKKILAERRKVLAIDHLNEDQLREKAKE 229
+Q+ + + K Q +RE ++K E ++ LA L E+Q +KAKE
Sbjct: 729 AERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQ-EKKAKE 778
Score = 61.2 bits (147), Expect = 1e-09
Identities = 61/245 (24%), Positives = 109/245 (44%), Gaps = 29/245 (11%)
Query: 32 ETEETRAEEDEEEEEAKEAEDGPMEESKPKPRSFMPNLVPPKIPDGERVDFDDIHRKRME 91
E E R E +EEA++ +EE K + L K+ ER+ R+R+E
Sbjct: 532 EKERQRLENLRRKEEAEQLRRQKVEEDKRR------RLEEVKLKREERLRKVLQARERVE 585
Query: 92 KDLNELQALIEAHFENRKKEEEELVSLKDRIERRRAERAEQQRIRNEREKERQNRLAEER 151
+ E + IE F ++ E K + ER E+A+++ + E+ R EE
Sbjct: 586 QMKEEKKKQIEQKFAQIDEKTE-----KAKEERLAEEKAKKKAAAKKMEEVEARRKQEEE 640
Query: 152 ARR-----EEEENRRKAEDEARKKKALSNMMHFGGYIQKAQTERKSGKRQTEREKKKKIL 206
ARR +EEE RR E +KK+ + ++ +R+ +R+ ER ++++
Sbjct: 641 ARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERRE 700
Query: 207 AERRKVLAIDHLNEDQLREKAKELWQSIYNLEAEKF----DLQEKFKQQKYEINVLRNRI 262
ERR E + RE+ ++L + E E+ +LQE+ K + + L+ +
Sbjct: 701 QERR---------EQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQREL 751
Query: 263 NDNQK 267
+ +K
Sbjct: 752 EEKKK 756
Score = 60.1 bits (144), Expect = 2e-09
Identities = 49/174 (28%), Positives = 84/174 (48%), Gaps = 47/174 (27%)
Query: 5 EEVVEEYEEEEQEEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDGPMEESKPKPRS 64
+E++++ +EEEQE +AAE AE + E+ R E++ E+E +E E E
Sbjct: 657 QELLQKKKEEEQERLRKAAEAKRLAE-QREQERREQERREQERREQERREQE-------- 707
Query: 65 FMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHFENRKKEEEELVSLKDRIER 124
R+ E+ L E + R++E+E L + ++ ER
Sbjct: 708 ----------------------RREQERQLAE---------QERRREQERLQAERELQER 736
Query: 125 RRAERAEQQRIRNERE----KERQNRLAEERARREEEENRRKAEDEARKKKALS 174
+A R ++++++ E E KE Q RLAE R+ +EE +KA++ A KAL+
Sbjct: 737 EKALRLQKEQLQRELEEKKKKEEQQRLAE---RQLQEEQEKKAKEAAGASKALN 787
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 67.8 bits (164), Expect = 1e-11
Identities = 57/276 (20%), Positives = 126/276 (45%), Gaps = 30/276 (10%)
Query: 9 EEYEEEEQEEQEEAAEEDAEAEAETEET--RAEEDEEEEEAKEAEDGPMEESKPKPRSFM 66
EE +++ +E Q+ +E+ E E ET R EE++ +EE + + EE +
Sbjct: 224 EEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQL----- 278
Query: 67 PNLVPPKIPDGERVDFDDIHRKRMEKD-----LNELQALIEAHFENRKKEEEELVSLKDR 121
+++ ++ R+R E++ L Q L E R++++EE ++R
Sbjct: 279 -----------RKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQER 327
Query: 122 IERRRAERAEQQRIRNEREKERQNRLAEERARREEEENRRKAEDEARKKKALSNMMHFGG 181
E++ R +Q R E +E+Q R +E RRE++ R + E+ ++ +
Sbjct: 328 REQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQ 387
Query: 182 YIQKAQTERKSGKRQTEREKKKKILAERRKVLAIDHLNEDQLREKAKELWQSIYNLEAEK 241
+++ Q R+ + + E++ +++ R + L E QLR + +E + + E+
Sbjct: 388 QLRREQQLRREQQLRREQQLRREQQLRREQQLR----REQQLRREQEE---ERHEQKHEQ 440
Query: 242 FDLQEKFKQQKYEINVLRNRINDNQKVSKTRGKAKV 277
+++ K+++ E R + ++ + R K ++
Sbjct: 441 ERREQRLKREQEERRDWLKREEETERHEQERRKQQL 476
Score = 67.8 bits (164), Expect = 1e-11
Identities = 61/266 (22%), Positives = 123/266 (46%), Gaps = 24/266 (9%)
Query: 5 EEVVEEYEEEEQEEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDGPMEESKPKPRS 64
+E+ +Y +EE+ +QEE E E + R + EEEE ++ E+ + E + K R
Sbjct: 1074 QELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRR 1133
Query: 65 FMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHFENRKKEEEELVSLKDRIER 124
+ + + E V ++ R E + Q L + E + ++EE L++ E+
Sbjct: 1134 ---QELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEK 1190
Query: 125 RRAERAEQQRIRNEREKERQNRLAEERARREEEENRRKAEDEARKKKALSNMMHFGGYIQ 184
RR ER +++ R E E +RQ R ++R R E++ + K + E K+ A ++
Sbjct: 1191 RRQER--ERQYREEEELQRQKR--KQRYRDEDQRSDLKWQWEPEKENA----------VR 1236
Query: 185 KAQTERKSGKRQTEREKKKKILAERRKVLAIDHL---NEDQLREKAKELWQSIYNLEAEK 241
+ K + + R+ + L +R+ + HL +++ RE+ + WQ
Sbjct: 1237 DNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQ----RDRH 1292
Query: 242 FDLQEKFKQQKYEINVLRNRINDNQK 267
F +E+ ++++ + R+R + +K
Sbjct: 1293 FPEEEQLEREEQKEAKRRDRKSQEEK 1318
Score = 67.4 bits (163), Expect = 1e-11
Identities = 67/282 (23%), Positives = 122/282 (43%), Gaps = 28/282 (9%)
Query: 9 EEYEEEEQEEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDGPMEESKPK-----PR 63
EE E EQE +++ + D E E + EE+E E+ + E E + + R
Sbjct: 462 EETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKR 521
Query: 64 SFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHFENRKKEEEELVSLKDRIE 123
+ ++ +++ + R+ E + L + E R K E+E +D++
Sbjct: 522 QEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQE--ERRDQLL 579
Query: 124 RRRAERAEQQRIRNEREKERQNRLAEERARREEEENRRKA-------EDEARKK--KALS 174
+R ER QQR++ E+E+ + RL E R E+E RR+ E+E R++ K+
Sbjct: 580 KREEER-RQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEE 638
Query: 175 NMMHFGGYIQKAQTERKSGKRQTEREKK------KKILAERRKVLAIDHLNEDQLREKAK 228
+++ Q ER+ + + E E++ K+ E R+ + ++Q RE+ K
Sbjct: 639 QEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIK 698
Query: 229 E---LWQSIYNLEAEKFDLQEKFKQQKYEINVLRNRINDNQK 267
WQ + LE+E Q K + + R R +K
Sbjct: 699 SRIPKWQ--WQLESEADARQSKVYSRPRKQEGQRRRQEQEEK 738
Score = 67.4 bits (163), Expect = 1e-11
Identities = 59/252 (23%), Positives = 118/252 (46%), Gaps = 21/252 (8%)
Query: 12 EEEEQEEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDGPMEESKPKPRSFMPNLVP 71
EEE+++ + + E + E + EE + + E ++ +E EDG ++E + + RS
Sbjct: 814 EEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDG-LQEDQERRRS-----QE 867
Query: 72 PKIPDGERVDFDDIHRKRMEKDLNELQALIEAHFENRK--KEEEELVSLKDRIERRRAER 129
+ R ++ RKR L AL E + ++ +EEEE + ++R +RRR E+
Sbjct: 868 QRRDQKWRWQLEE-ERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQ 926
Query: 130 AEQQRIRNEREKERQNRLAEERARREEEENRRKAEDEARKKKALSNMMHFGGYIQKAQTE 189
Q R + ++E + L EER +R +E R + RK K L ++ Q
Sbjct: 927 ERQYREEEQLQQEEEQLLREEREKRRRQERER----QYRKDKKLQQ--------KEEQLL 974
Query: 190 RKSGKRQTEREKKKKILAERRKVLAIDHLNEDQLREKAKELWQSIYNLEAEKFDLQEKFK 249
+ +++ +E++KK E + L ++ ++ ++ W+ Y + E +E+
Sbjct: 975 GEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLL 1034
Query: 250 QQKYEINVLRNR 261
+++ E L+ R
Sbjct: 1035 REEREKRRLQER 1046
Score = 67.4 bits (163), Expect = 1e-11
Identities = 61/254 (24%), Positives = 118/254 (46%), Gaps = 19/254 (7%)
Query: 4 IEEVVEEYEEEEQEEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDGPMEESKPKPR 63
++E +Y EEE+ +QEE E E + + +EEE ++ E+ + E K R
Sbjct: 1043 LQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRR 1102
Query: 64 SFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHFENRKKEEEELVSLKDRIE 123
+ + E + ++ R E++ Q L + E + ++EE L++ E
Sbjct: 1103 R---QERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPE 1159
Query: 124 RRRAERAEQQRIRNEREKERQNRLAEERARREEEENRRKAEDEARKKKALSNMMHFGGYI 183
+RR + E+Q RE+E + E+ R E+E+ R++ E + R+++ L Y
Sbjct: 1160 KRRRQELERQ----YREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRY- 1214
Query: 184 QKAQTERKSGKRQTEREKK-----KKILAERRKVLAIDHLNEDQLREKAKELWQSIYNLE 238
+ + +R K Q E EK+ K+ + R+ L + QLR++ + Q + +L
Sbjct: 1215 -RDEDQRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQ--QDLQHLL 1271
Query: 239 AEKFDLQEKFKQQK 252
E+ QE+ ++Q+
Sbjct: 1272 GEQ---QERDREQE 1282
Score = 66.2 bits (160), Expect = 3e-11
Identities = 60/243 (24%), Positives = 116/243 (47%), Gaps = 28/243 (11%)
Query: 12 EEEEQEEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDGPMEESKPKPRSFMPNLVP 71
E +E+E+Q++ + + + EE R E+ EE E +E + E + + R
Sbjct: 289 ERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERRE 348
Query: 72 PKIPDGERVDFDDIHRKRMEKDLNELQALIEAHFENRKKE--EEELVSLKDRIERRRAER 129
++ R+ E++ E Q E E R+++ E+ + + ++ R + R
Sbjct: 349 QQL------------RREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLR 396
Query: 130 AEQQRIRNEREKERQNRLAEERARREEEENRRKAEDEARKKKALSNMMHFGGYIQKAQTE 189
EQQ +R E++ R+ +L E+ R E++ RR+ E+E ++K +++ Q E
Sbjct: 397 REQQ-LRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERRE--QRLKREQEE 453
Query: 190 RKSG-KRQTEREKKKKILAERRKVLAIDHLNEDQLREKAKELWQSIYNLEAEKFDLQEKF 248
R+ KR+ E E+ ++ ERRK + E++ RE+ W + E E+ + QE+
Sbjct: 454 RRDWLKREEETERHEQ---ERRKQ-QLKRDQEEERRER----WLKLE--EEERREQQERR 503
Query: 249 KQQ 251
+QQ
Sbjct: 504 EQQ 506
Score = 66.2 bits (160), Expect = 3e-11
Identities = 55/244 (22%), Positives = 117/244 (47%), Gaps = 8/244 (3%)
Query: 9 EEYEEEEQEEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDGPMEESKPKPRSFMPN 68
+E + QE++E+ ++E + + EE + +EEE+ ++ E K + +
Sbjct: 726 QEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLS 785
Query: 69 LVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHFENRKKEEEELVSLKDRIERRRAE 128
PP ER + ++R ++ L E + E R++ E+EL L++ + +R E
Sbjct: 786 ARPPLREQRERQLRAEERQQREQRFLPEEEEK-EQRRRQRREREKELQFLEEEEQLQRRE 844
Query: 129 RAEQQRIRNEREKERQNRLAEERARREEEENRRKAEDEARKKKALSNMMHFGGYIQKAQT 188
RA+Q + + +E Q R + RR+++ + E+ R++ L ++K Q
Sbjct: 845 RAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQ 904
Query: 189 ERKSGKRQTEREKKKKILAERRKVLAIDHLNEDQLREKAKELWQSIYNLEAEKFDLQEKF 248
+ + + +RE+++K RR+ + E+QL+++ ++L + E EK QE+
Sbjct: 905 LLQEEEEELQREEREK---RRRQEQERQYREEEQLQQEEEQLLRE----EREKRRRQERE 957
Query: 249 KQQK 252
+Q +
Sbjct: 958 RQYR 961
Score = 66.2 bits (160), Expect = 3e-11
Identities = 63/259 (24%), Positives = 121/259 (46%), Gaps = 30/259 (11%)
Query: 9 EEYEEEEQEEQEEAAEEDAEAEAETEETRAEEDE----EEEEAKEAEDGPMEESKPKPRS 64
EE EE ++EE+E+ ++ E + EE +E+E EE E + ++ + K K
Sbjct: 908 EEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQ 967
Query: 65 FMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHFENRKKEEEELVSLKDRIER 124
+ + P+ R R+ EK E E ++EEE + ++R +R
Sbjct: 968 QKEEQLLGEEPEKRR-------RQEREKKYRE---------EEELQQEEEQLLREEREKR 1011
Query: 125 RRAERAEQQRIRNEREKERQNRLAEERARREEEENRRKAEDEARKKKALSNMMHFGGYIQ 184
RR E Q R ++E ++E + L EER +R +E R+ +E ++ ++ +
Sbjct: 1012 RRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETR 1071
Query: 185 KAQ-TERKSGKRQTEREKKKKILAE-----RRKVLAIDHLNEDQLREKAKELWQSIYNLE 238
+ Q ER+ K + +++++++L E RR+ E++L+++ ++L + E
Sbjct: 1072 RRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLRE----E 1127
Query: 239 AEKFDLQEKFKQQKYEINV 257
EK QE +Q + E V
Sbjct: 1128 REKRRRQELERQYREEEEV 1146
Score = 65.9 bits (159), Expect = 4e-11
Identities = 61/278 (21%), Positives = 123/278 (44%), Gaps = 51/278 (18%)
Query: 8 VEEYEEEEQEEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDGPMEESKPKPRSFMP 67
+EE + ++E+E+ D + + EE +E EE++ ++ D E + + R
Sbjct: 1646 LEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLR---- 1701
Query: 68 NLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHFENRKKEEEELVSLKDRIERRRA 127
++R K L E Q L E + +EEE+L ++ + RR
Sbjct: 1702 ------------------RQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQ 1743
Query: 128 ER----AEQQRIRNEREKERQNRLAEERARREEEENRRKAED------EARKKKALSNMM 177
ER E++++R ERE+++ R +R REEE+ R++ E+ E+ +K +
Sbjct: 1744 ERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQL 1803
Query: 178 HFGGYIQKAQTERKSGKRQTE------REKKKKILAERRKVLAIDH--LNEDQLREKAKE 229
Q+ + +++ GK + E E+++++ ER + + +++ R + +E
Sbjct: 1804 RQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQE 1863
Query: 230 LWQSIYNLEAEKFDLQEKFKQQKYEINVLRNRINDNQK 267
LWQ +E+ ++Q+ E + I QK
Sbjct: 1864 LWQE-----------EEQKRRQERERKLREEHIRRQQK 1890
Score = 65.5 bits (158), Expect = 5e-11
Identities = 67/276 (24%), Positives = 124/276 (44%), Gaps = 56/276 (20%)
Query: 9 EEYEEEEQEEQEEAAEEDAEAEAETEETRAEEDE----EEEEAKEAEDGPMEESKPKPRS 64
+E+E + +++ E EE+ E E+ R +E E EEEE ++ E+ + E + R
Sbjct: 1014 QEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRR- 1072
Query: 65 FMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHFENRK-------KEEEELVS 117
R + + +RK E E Q L E + R+ +EEEEL
Sbjct: 1073 --------------RQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQ 1118
Query: 118 LKDRIERRRAERAEQQRIRNEREKERQNRLAEERARREEEENRRKAEDEARKKKALSNMM 177
++++ R E+ +Q + + +E + + EE+ REE E RR+ E E + ++
Sbjct: 1119 EEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYRE------ 1172
Query: 178 HFGGYIQKAQTERKSGKRQTEREKKKKILAERRKVLAIDHLNEDQL-REKAKELWQSIYN 236
+ E + + Q RE+++K ER + + E++L R+K K+ Y
Sbjct: 1173 ---------EEELQQEEEQLLREEQEKRRQERER----QYREEEELQRQKRKQR----YR 1215
Query: 237 LEAEKFDLQEKFKQQKYEINVLRNRINDNQKVSKTR 272
E ++ DL+ +++ +K N + DN+ K R
Sbjct: 1216 DEDQRSDLKWQWEPEK------ENAVRDNKVYCKGR 1245
Score = 65.1 bits (157), Expect = 7e-11
Identities = 57/250 (22%), Positives = 118/250 (47%), Gaps = 24/250 (9%)
Query: 5 EEVVEEYEEEEQEEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDGPMEESKPKPRS 64
E+ ++ EEEEQ ++ E A++ E E +E + +E+ + +EE + + R
Sbjct: 828 EKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRH 887
Query: 65 FMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHFENRKKEEEELVSLKDRIER 124
+ P + + R + + + E E + E + +EEE+L ++++ R
Sbjct: 888 TL--YAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLR 945
Query: 125 RRAERAEQQRIRNEREKERQNRLAEERARREEEENRRKAEDEARKKKALSNMMHFGGYIQ 184
E+ +Q + K+++ + EE+ EE E RR+ E E + ++ +
Sbjct: 946 EEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREE-----------E 994
Query: 185 KAQTERKSGKRQTEREKKKKILAERRKVLAIDHLNEDQLREKAKELWQSIYNLEAEKFDL 244
+ Q E + R+ EREK+++ ER+ + +D+L+++ ++L + E EK L
Sbjct: 995 ELQQEEEQLLRE-EREKRRRQEWERQ------YRKKDELQQEEEQLLRE----EREKRRL 1043
Query: 245 QEKFKQQKYE 254
QE+ +Q + E
Sbjct: 1044 QERERQYREE 1053
Score = 63.2 bits (152), Expect = 3e-10
Identities = 56/260 (21%), Positives = 121/260 (46%), Gaps = 23/260 (8%)
Query: 13 EEEQEEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDGPMEESKPKPRSFMPNLVPP 72
E+E+E +E+ + E E ++ R E+ E+ E E + + +
Sbjct: 354 EQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRR--EQ 411
Query: 73 KIPDGERVDFDDIHRKRMEKDLNELQALIEAHFENRKKEEEEL---VSLKDRIERRRAER 129
++ +++ + R+ E++ +E + E + K+E+EE + ++ ER ER
Sbjct: 412 QLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQER 471
Query: 130 AEQQRIRNEREKERQNRLA-------------EERARREEEENRRKAEDEARKKKALSNM 176
+QQ R++ E+ R+ L E++ RRE+EE R + +++ L
Sbjct: 472 RKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQR 531
Query: 177 MHFGGYIQKAQTERKSGKRQTEREKKKKILAERR--KVLAIDHLNEDQLREKAKELWQSI 234
+ +++ Q ER+ ++ +RE++K++ ERR ++ DQL ++ +E Q
Sbjct: 532 LRSEQQLRREQEERR--EQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQR 589
Query: 235 YNLEAEKFDLQEKFKQQKYE 254
E E+ L+++ K+++ E
Sbjct: 590 LKREQEE-RLEQRLKREEVE 608
Score = 61.2 bits (147), Expect = 1e-09
Identities = 65/280 (23%), Positives = 128/280 (45%), Gaps = 29/280 (10%)
Query: 5 EEVVEEYEEEEQEEQEEAA---EEDAEAEAETEETRAEEDEEEEEAKEAEDGPMEESKPK 61
+E ++ EEE QE+ EE+ + E + ++E++ +E E ++ K
Sbjct: 1356 QERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRK 1415
Query: 62 PRSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHFENRKKEEEELVSLKDR 121
R L + R + + R+ E+ E + + + +EEE+L+
Sbjct: 1416 FREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQ---- 1471
Query: 122 IERRRAERAEQQRIRNEREKERQNRLAEERARREEEENRRKAEDEARKKKALSNMMHFGG 181
ER EQQ R ER+++ L EE+ R +E +R+ E E R ++ +
Sbjct: 1472 ------EREEQQLHRQERDRK---FLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQ 1522
Query: 182 YIQKAQTERK--SGKRQTEREKKKKILAERRKVLAIDHLNEDQLREKAKELWQSIYNLEA 239
+ + Q +RK ++Q R+++ + +RR+ E+QLR++ +E Q + E
Sbjct: 1523 QLHRQQRQRKFLQEEQQLRRQERGQ---QRRQDRDRKFREEEQLRQEREE--QQLSRQER 1577
Query: 240 E-KFDLQE-KFKQQKYEINVLRNRINDNQKVSKTRGKAKV 277
+ KF L+E K ++Q+ E R + D Q++ + G+ ++
Sbjct: 1578 DRKFRLEEQKVRRQEQE----RKFMEDEQQLRRQEGQQQL 1613
Score = 58.9 bits (141), Expect = 5e-09
Identities = 58/275 (21%), Positives = 131/275 (47%), Gaps = 22/275 (8%)
Query: 5 EEVVEEYEEEEQ------EEQEEAAEEDAEAEAETEETRAE-EDEEEEEAKEAEDGPMEE 57
+E E EEEQ E EE +E+ E E R + +E++++ +E +D +E
Sbjct: 181 QEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQE 240
Query: 58 SKPKPRSFMPNLVPPKIPDGERVDFDDIHRKR-MEKDLNELQALIEAHFENRKKEEEELV 116
+ K ++ + E++ ++ R+R ++++ +L+ L ++EEE+
Sbjct: 241 EEEKEWRKRETVLRK---EEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQ 297
Query: 117 SLKDRIERRRAERAEQQRIRNEREKERQNRLAEERARRE-----EEENR-----RKAEDE 166
R ++ R ++ E++R + E +E+Q R ++ RRE E+E R R+ ++E
Sbjct: 298 QRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEE 357
Query: 167 ARKKKALSNMMHFGGYIQKAQTERKSGKRQTEREKKKKILAERRKVLAIDHLNEDQLREK 226
R+++ L Q+ + E++ +R+ + +++++ E++ E QLR +
Sbjct: 358 ERREQQLRREQEEERREQQLRREQQL-RREQQLRREQQLRREQQLRREQQLRREQQLRRE 416
Query: 227 AKELWQSIYNLEAEKFDLQEKFKQQKYEINVLRNR 261
+ + E E+ ++K +Q++ E + R +
Sbjct: 417 QQLRREQQLRREQEEERHEQKHEQERREQRLKREQ 451
Score = 58.5 bits (140), Expect = 6e-09
Identities = 65/292 (22%), Positives = 136/292 (46%), Gaps = 57/292 (19%)
Query: 5 EEVVEEYEEEE--QEEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDGPMEESKP-- 60
+E+ +Y EEE Q+E+E+ E+ E + E + E+EE + K + E+ +
Sbjct: 1164 QELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDL 1223
Query: 61 -------KPRSFMPNLVPPKIPDGER---VDFDDIHRKRMEKDLNELQALIEAHFENRKK 110
K + N V K + E+ ++ + ++ ++DL L L E +R++
Sbjct: 1224 KWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHL--LGEQQERDREQ 1281
Query: 111 E------------EEELVSLKDRIERRRAERA---EQQRIRNEREKERQNRLAEERAR-- 153
E EEE + +++ E +R +R E+Q +R ERE++R+ + + + R
Sbjct: 1282 ERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREE 1341
Query: 154 ------REEEENRRKAEDEARKKKALSNMMHFGGYIQKAQTERKSGKRQTEREKKKKILA 207
REE+ RR+ D +++ L + ++++ Q R+ +E+++K L
Sbjct: 1342 EQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRR-------QERERKFLK 1394
Query: 208 ERRKVLAIDHLNEDQLRE----KAKELWQSIYNLEAEKFDLQEKFKQQKYEI 255
E +++ + E QLR+ K +E Q + E ++ KF++++ ++
Sbjct: 1395 EEQQLRCQE--REQQLRQDRDRKFREEEQQLSRQERDR-----KFREEEQQV 1439
Score = 56.6 bits (135), Expect = 2e-08
Identities = 67/299 (22%), Positives = 129/299 (43%), Gaps = 50/299 (16%)
Query: 5 EEVVEEYEEEEQEEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDGPMEESKPKP-R 63
+++++ EE Q+ + EE E + EE E EE E + + P EE + + +
Sbjct: 576 DQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLK 635
Query: 64 SFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHFENRKKEE---EELVSLKD 120
S + E+ + + KR E++ Q L H E R+++E EE ++
Sbjct: 636 SEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARE 695
Query: 121 RIERR---------------------RAERAEQQRIRNEREKERQNRLAEERARREEEEN 159
RI+ R R + E QR R E+E++R+ R +E + + EE +
Sbjct: 696 RIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAH 755
Query: 160 RRKAEDEARK---------KKALSNMMHFGG-------------YIQKAQTERKSGKRQT 197
R++ E+E R+ +K+ ++ Q E++ +
Sbjct: 756 RQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEE 815
Query: 198 EREKKKKILAERRKVLA-IDHLNEDQLREKAKELWQSIYNL--EAEKFDLQEKFKQQKY 253
E+E++++ ER K L ++ + Q RE+A++L + L + E+ QE+ + QK+
Sbjct: 816 EKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKW 874
Score = 55.5 bits (132), Expect = 5e-08
Identities = 57/248 (22%), Positives = 113/248 (45%), Gaps = 29/248 (11%)
Query: 5 EEVVEEYEEEEQEEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDGPMEESKPKPRS 64
E ++++ +EE + + E + E E + R + E+E E E E+ ++ + + R
Sbjct: 107 ESLLQDRRQEEDQRRFEPRDRQLEEEPG-QRRRQKRQEQERELAEGEEQSEKQERLEQR- 164
Query: 65 FMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHFENRKKEEEELVSLKDRIER 124
D +R D +++ R+R E E R+ EEE+L S K E
Sbjct: 165 -----------DRQRRD-EELWRQRQEWQERE----------ERRAEEEQLQSCKGH-ET 201
Query: 125 RRAERAEQQRIRNEREKERQNRLAEERARREEEENRRKAEDEARKKKALSNMMHFGGYIQ 184
EQ R R E R+ R +++ RRE ++ + E+E +K + + +Q
Sbjct: 202 EEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQ 261
Query: 185 KAQTERKSGKRQTEREKKKKILAERRKVLAIDHLNEDQLREKAKELWQSIYNLEAEKFDL 244
+ + +R+ + Q E E+ +K+ R+ L + E+Q +++ + Q E E+ +
Sbjct: 262 EEEPQRQR-ELQEEEEQLRKL---ERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQ 317
Query: 245 QEKFKQQK 252
QE+ ++Q+
Sbjct: 318 QEERREQQ 325
Score = 53.9 bits (128), Expect = 2e-07
Identities = 53/245 (21%), Positives = 108/245 (44%), Gaps = 41/245 (16%)
Query: 10 EYEEEEQEEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDGPMEESKPKPRSFMPNL 69
E E+ E+EEQ+EA D +++ E + R E +E+ + EE + R P
Sbjct: 1295 EEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQP-- 1352
Query: 70 VPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHFENRKKEEEELVSLKDRIERRRAER 129
+R E+D + + + RK EEE R+ R+ ER
Sbjct: 1353 -----------------LRRQERDRKFREEELRHQEQGRKFLEEE-----QRLRRQERER 1390
Query: 130 AEQQRIRNEREKERQNRLAEERARREEEENRRKAEDEARKKKALSNMMHFGGYIQKAQTE 189
+ + R +ER+ +L ++R R+ EE ++ + E +K + ++ Q
Sbjct: 1391 KFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRK-----------FREEEQQV 1439
Query: 190 RKSGKRQTEREKKKKILAERRKVLAIDHLNEDQLREKAKELWQSIYNLEAEKFDLQEKFK 249
R+ + + E+++++ ER + E+QL ++ +E Q ++ E ++ L+E+ +
Sbjct: 1440 RRQERERKFLEEEQQLRQERHRKFR----EEEQLLQEREE--QQLHRQERDRKFLEEEQQ 1493
Query: 250 QQKYE 254
++ E
Sbjct: 1494 LRRQE 1498
Score = 52.8 bits (125), Expect = 3e-07
Identities = 51/261 (19%), Positives = 120/261 (45%), Gaps = 12/261 (4%)
Query: 4 IEEVVEEYEEEEQEEQEEAAEEDAEAEAETEETRAE-----EDEEEEEAKEAEDGPMEES 58
+E+ ++ EEE+ EQE A EE +A + + E E + + P ++
Sbjct: 668 LEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQE 727
Query: 59 KPKPRSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNE---LQALIEAHFENRKKEEEEL 115
+ R + + + + + HR++ E++ Q E E ++
Sbjct: 728 GQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSAR 787
Query: 116 VSLKDRIERR-RAERAEQQRIRNEREKERQNRLAEERARREEEENRRKAEDEARKKKALS 174
L+++ ER+ RAE +Q+ R E+E + + +R RE+E + E++ ++++
Sbjct: 788 PPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQ 847
Query: 175 NMMHFGGYIQKAQTERKSGKRQTEREKKKKILAE---RRKVLAIDHLNEDQLREKAKELW 231
+ +Q+ Q R+S +++ +++ + ++ E RR L ++QLR++ + L
Sbjct: 848 QLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQ 907
Query: 232 QSIYNLEAEKFDLQEKFKQQK 252
+ L+ E+ + + + +Q++
Sbjct: 908 EEEEELQREEREKRRRQEQER 928
Score = 52.8 bits (125), Expect = 3e-07
Identities = 62/285 (21%), Positives = 122/285 (42%), Gaps = 42/285 (14%)
Query: 5 EEVVEEYEEEE---QEEQEEAAEEDAEAEAETEETRAEEDE---EEEEAKEAEDGPMEES 58
E++++E EE++ QE + EE+ + + + + E E +E E K E+
Sbjct: 1467 EQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHR 1526
Query: 59 KPKPRSFMPN---LVPPKIPDGERVDFD-------DIHRKRMEKDLNELQALIEAHFENR 108
+ + R F+ L + R D D + ++R E+ L+ + + E +
Sbjct: 1527 QQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQ 1586
Query: 109 K--KEEEELVSLKDRIERRRAERAEQQRIRNEREK--------------------ERQNR 146
K ++E+E ++D + RR E QQ++R ER++ ER +
Sbjct: 1587 KVRRQEQERKFMEDEQQLRRQEG--QQQLRQERDRKFREDEQLLQEREEQQLHRQERDRK 1644
Query: 147 LAEERAR-REEEENRRKAEDEARKKKALSNMMHFGGYIQKAQTERKSGKRQTEREKKKKI 205
EE + R +E ++ D RK + ++ G Q + ER R+ E++ +++
Sbjct: 1645 FLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQ- 1703
Query: 206 LAERRKVLAIDHLNEDQLREKAKELWQSIYNLEAEKFDLQEKFKQ 250
ER+ + L +L K +E Q E E+ QE++++
Sbjct: 1704 ERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRK 1748
Score = 52.4 bits (124), Expect = 4e-07
Identities = 62/266 (23%), Positives = 122/266 (45%), Gaps = 35/266 (13%)
Query: 1 MSDIEEVVEEYEEEEQEEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDGPMEE--- 57
+ + +++ +E + +EE++ E + + E R +EE++ ++ D E
Sbjct: 1449 LEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQEL 1508
Query: 58 -SKPKPRSFMPNLVPPKIPDGERVDFDDIHR-KRMEKDLNELQALIEAHFENRKKEEEEL 115
S+ R F+ + +HR +R K L E Q L +++++ +
Sbjct: 1509 RSQEPERKFLE-------------EEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDR 1555
Query: 116 VSLKDRIERRRAERAEQQRIRNEREKERQNRLAEERARREEEENR-RKAEDEARKKKALS 174
++ E+ R ER EQQ R ER +R+ RL E++ RR+E+E + + E + R+++
Sbjct: 1556 KFREE--EQLRQEREEQQLSRQER--DRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQ 1611
Query: 175 NMMHFGGYIQKAQTERKSGKRQTEREKKKKILAER-RKVLAIDHLNEDQLREKAKELWQS 233
+ ++ + R+ + ERE+++ ER RK L E QLR + +E Q
Sbjct: 1612 QLRQ-----ERDRKFREDEQLLQEREEQQLHRQERDRKFLE----EEPQLRRQERE--QQ 1660
Query: 234 IYNLEAEKFDLQEKFKQQKYEINVLR 259
+ + KF +E+ Q+ E + R
Sbjct: 1661 LRHDRDRKFREEEQLLQEGEEQQLRR 1686
Score = 49.7 bits (117), Expect = 3e-06
Identities = 41/201 (20%), Positives = 89/201 (44%), Gaps = 10/201 (4%)
Query: 5 EEVVEEYEEEEQEEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDGPMEESKPKPRS 64
E+ + E E + +EE ++ E E + R + EEE+ + + + + R
Sbjct: 1713 EQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRK 1772
Query: 65 FMPNLVPPKIPDGERVDFDDIHRKRMEKDL----NELQALIEAHFENRKKEEEELVSLKD 120
F + + +++ + RK E++ E Q L + + + EEE + L++
Sbjct: 1773 FREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEE 1832
Query: 121 RIERRRAERAEQQRIRNEREKERQNRLAEERARREEEENRRKAEDEARKKKALSNMMHFG 180
+ +R R ER Q R + + ++R E+ +EEE+ RR+ + +++ H
Sbjct: 1833 QEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREE------HIR 1886
Query: 181 GYIQKAQTERKSGKRQTEREK 201
++ Q R+ G+ +++ K
Sbjct: 1887 RQQKEEQRHRQVGEIKSQEGK 1907
Score = 46.6 bits (109), Expect = 2e-05
Identities = 55/230 (23%), Positives = 99/230 (43%), Gaps = 40/230 (17%)
Query: 5 EEVVEEYEEEE---QEEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDGPMEESKPK 61
E+ + E E QEEQ+ +E E E+ R E ++E+ +E +EE + +
Sbjct: 1697 EQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLR 1756
Query: 62 PRSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHFENRKKEEEELVSLKDR 121
P L + D + + + + ++R E+ L ++ + + +EEE+L R
Sbjct: 1757 PEREEQQLRRQE-RDRKFREEEQLRQEREEQQLRSQES------DRKFREEEQL-----R 1804
Query: 122 IERRRAERAEQQRIRNEREKERQNRLAEE--RARREEEENRRKAEDEARKKKALSNMMHF 179
ER + QQR R +E Q +L E+ R R+E + R E A ++K+
Sbjct: 1805 QEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRRE---- 1860
Query: 180 GGYIQKAQTERKSGKRQTEREKKKKILAERRKVLAIDHLNEDQLREKAKE 229
++ + + KR+ ERE+K L E+ +R + KE
Sbjct: 1861 ----EQELWQEEEQKRRQERERK---------------LREEHIRRQQKE 1891
Score = 39.7 bits (91), Expect = 0.003
Identities = 50/227 (22%), Positives = 99/227 (43%), Gaps = 41/227 (18%)
Query: 77 GERVDFDDIHRKRMEKDLNELQALIEAHFENRKKEEEELVSLKDRI------ERRRAERA 130
G+ D+ R R + + LQ + R++E++ +DR +RRR +R
Sbjct: 90 GQATGLDEEKRARCDGKESLLQ-------DRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQ 142
Query: 131 EQQR--IRNEREKERQNRLAEERARRE------------EEENRRKAEDEARKKKALSNM 176
EQ+R E + E+Q RL E+R R+ +E R+AE+E +
Sbjct: 143 EQERELAEGEEQSEKQERL-EQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHET 201
Query: 177 MHFGGYIQKAQTE----RKSG---KRQTEREKKKKILAER-----RKVLAIDHLNEDQLR 224
F Q + E R+ G K+Q RE++ ++ E RK + E++L+
Sbjct: 202 EEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQ 261
Query: 225 EKAKELWQSIYNLEAEKFDLQ-EKFKQQKYEINVLRNRINDNQKVSK 270
E+ + + + E + L+ ++ ++++ E + R+ Q++ +
Sbjct: 262 EEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRR 308
>gi|169218106 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 436
Score = 67.4 bits (163), Expect = 1e-11
Identities = 45/226 (19%), Positives = 112/226 (49%), Gaps = 26/226 (11%)
Query: 1 MSDIEEVVEEYEEEEQEEQEEAAEEDAEAEAETEETRAEED---EEEEEAKEAEDGPMEE 57
M + EE + + EE+ E++E+ +++ + + + E+ R +E+ E+EE+ +E E+ +++
Sbjct: 222 MGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQ 281
Query: 58 SKPKPRSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHFENRKKEEEELVS 117
+ + ++ + E + E+ + E + + E K+EE++
Sbjct: 282 KEQTEQEEQTGEQEEQMREQEE------QMREQEEQMREQEEQMREQEEQMGKQEEQMWE 335
Query: 118 LKDRI----------ERRRAERAEQQRIRNE--REKERQNRLAEERARREEEENRRKAED 165
K+++ E + E+ EQ + + E R++E Q R EE+ R++EE+ R++ E
Sbjct: 336 QKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQ 395
Query: 166 EARKKKALSNMMHFGGYIQKAQTERKSGKRQTEREKKKKILAERRK 211
+K+ + Q + E + G+++ + K+++ + E+++
Sbjct: 396 MGEQKEQMGEQKE-----QMREQEEQMGEQKEQMRKQEEHMGEQKE 436
Score = 63.5 bits (153), Expect = 2e-10
Identities = 50/254 (19%), Positives = 114/254 (44%), Gaps = 12/254 (4%)
Query: 12 EEEEQEEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDGPMEESKPKPRSFMPNLVP 71
E+E Q ++E + E + +E + E EE+ + +E + G EE K M
Sbjct: 182 EQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEE 241
Query: 72 PKIPDGERVDFDDIHRKRMEKDLNELQALIEAHFENRKKEEEELVSLKDRIERRRAERAE 131
E+V + ++ E+ + E + + E K++E+ + E+ R +
Sbjct: 242 QVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQ 301
Query: 132 QQRIRNE----REKERQNRLAEERARREEEENRRKAEDEARKKKALSNMMHFGGYIQKAQ 187
++++R + RE+E Q R EE+ ++EE+ + E +K+ + + Q+ Q
Sbjct: 302 EEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQM--------WKQEEQ 353
Query: 188 TERKSGKRQTEREKKKKILAERRKVLAIDHLNEDQLREKAKELWQSIYNLEAEKFDLQEK 247
+ + Q + E+ +K + RK E+Q+R++ +++ + + +K ++E+
Sbjct: 354 MGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQ 413
Query: 248 FKQQKYEINVLRNR 261
+Q + +R +
Sbjct: 414 EEQMGEQKEQMRKQ 427
Score = 60.1 bits (144), Expect = 2e-09
Identities = 47/263 (17%), Positives = 125/263 (47%), Gaps = 27/263 (10%)
Query: 5 EEVVEEYEEEEQEEQEEAAEEDAEAEAETEETRAEEDE--EEEEAKEAEDGPMEESKPKP 62
E V E E + +E++ + E++ + + + R +E + E+E ++G + E + +
Sbjct: 121 EGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQV 180
Query: 63 RSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHFENRKKEEEELVSLKDRI 122
R + + GE+ E + E + + E +K+EE++ ++++
Sbjct: 181 REQEGQVREQEGQMGEQ-----------EGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQM 229
Query: 123 ERRRAERAEQ----QRIRNEREKERQNRLAEERARREEEENRRKAEDEARKKKALSNMMH 178
++ + EQ Q+ + +K+ + +E RE+EE R+ E++ K+K +
Sbjct: 230 RKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEE 289
Query: 179 FGGYIQKAQTERKSGKRQTE---REKKKKILAERRKVLAIDHLNEDQLREKAKELW---Q 232
G ++ E++ R+ E RE+++++ + ++ E+Q+ E+ +++W +
Sbjct: 290 QTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQM----GKQEEQMWEQKEQMWEQKE 345
Query: 233 SIYNLEAEKFDLQEKFKQQKYEI 255
++ E + + +E+ ++Q+ ++
Sbjct: 346 QMWKQEEQMGEQEEQMQKQEEQV 368
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 67.4 bits (163), Expect = 1e-11
Identities = 57/291 (19%), Positives = 137/291 (47%), Gaps = 19/291 (6%)
Query: 5 EEVVEEYEEEEQEEQEEAAEEDAEAEAETEETRAEED---EEEEEAKEAEDGPMEESKPK 61
E+ + + EE+ ++E E++ + + E+ R +E E+E+E +E E E+ K +
Sbjct: 247 EKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQKKLR 306
Query: 62 PRSFMPNLVPPKI-PDGERVDFDDIHRKRMEKDLNELQALIEAHFENRKKEEEELVSLKD 120
+ K+ E++ + R E+ L E + + + + +EE + +
Sbjct: 307 EQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDE 366
Query: 121 RIERRRAERAEQQRIRNEREK-ERQNRLAE-ERARREEEENRRKAEDEARKKKALSNMMH 178
R+ + EQ+++ + EK + + R+ E E+ REEEE R+ E++ +K++
Sbjct: 367 RLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQE 426
Query: 179 FGGYIQKAQTERKSGKRQTER--EKKKKILAERRKVLAIDHL--------NEDQLREKAK 228
+ Q+ E+K + E+ E+++KI + K+ + + ++++RE+
Sbjct: 427 EKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQED 486
Query: 229 ELW---QSIYNLEAEKFDLQEKFKQQKYEINVLRNRINDNQKVSKTRGKAK 276
++W + + + E + +D +E+ +Q + R+ + +K+ + K +
Sbjct: 487 QMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMR 537
Score = 61.2 bits (147), Expect = 1e-09
Identities = 60/294 (20%), Positives = 131/294 (44%), Gaps = 27/294 (9%)
Query: 1 MSDIEEVVEEYEEEEQEEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDGPMEESKP 60
M + EE ++E E + E++ EE+ E E + + EE+ E+E KE + + E K
Sbjct: 381 MWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKE 440
Query: 61 K--PRSFMPNL------VPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHFENRKKE- 111
K + M KI D E + + R EK + + E + R +E
Sbjct: 441 KLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQ 500
Query: 112 -----EEELVSLKDRIERRRAERAEQQRIRNEREKERQNRLAEERARR---EEEENRRKA 163
EE + +R+ + EQ+++ + EK R+ + +E+ ++ +EE+ R +
Sbjct: 501 KMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEE 560
Query: 164 EDEARKKKALSNMMHFGGYIQKAQTERKSGKRQTER--EKKKKILAERRKVLAIDHL--- 218
R+KK +K Q + + + Q E+ E+++K+ + K+ +
Sbjct: 561 RMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWE 620
Query: 219 --NEDQLREKAKELW---QSIYNLEAEKFDLQEKFKQQKYEINVLRNRINDNQK 267
ED+++E+ + +W + + E + ++ +EK ++Q+ ++ ++ ++
Sbjct: 621 QEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEE 674
Score = 59.3 bits (142), Expect = 4e-09
Identities = 54/267 (20%), Positives = 126/267 (47%), Gaps = 26/267 (9%)
Query: 5 EEVVEEYEEEEQEEQEEAAEEDAEAEAETEETRAEEDE--EEEEAKEAEDGPMEESKPKP 62
E+ + +E+E+ +EQEE E E + EE +E + +E+ +E ED M E + K
Sbjct: 437 EQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQED-QMWEQEEKM 495
Query: 63 RSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALI--EAHFENRKKEEEELVSLKD 120
R + + ER+ D + E+ + E + + E KK +E+ D
Sbjct: 496 RDQEQKMWDQE----ERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWD 551
Query: 121 RIERRRAERAEQQRIRNEREKERQNRLAEERARREEEENRRKAEDEARKKKALSNMMHFG 180
+ E+ R E ++R + RE+E R EE+ + +EE+ R + E +++ +
Sbjct: 552 QEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQ------ 605
Query: 181 GYIQKAQTERKSGKRQTEREKKKKILAERRKVLAIDHLNEDQLREKAKELWQSIYNLEAE 240
++ + + ++ E+E++ K+ + + E++++E+ +++W+ E +
Sbjct: 606 ---EQEEKMWEQEEKMWEQEEEDKMQEQEEMMWE----QEEKMQEQEEKMWEQ----EEK 654
Query: 241 KFDLQEKFKQQKYEINVLRNRINDNQK 267
+ +EK ++Q+ ++ ++ + ++
Sbjct: 655 MREQEEKMREQEEKMQGQEEKMREQEE 681
Score = 56.2 bits (134), Expect = 3e-08
Identities = 60/284 (21%), Positives = 124/284 (43%), Gaps = 49/284 (17%)
Query: 12 EEEEQEEQEEAAEEDAEAEAETEETRAEEDEE--EEEAKEAEDGPMEESKPKPRSFMPNL 69
+E++ EQEE + + + EE E+DE E+E + E M + + K R
Sbjct: 484 QEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMWQQEEKMRE----- 538
Query: 70 VPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHFENRKKEEEELVSLKDRIERRRAER 129
K + E+ +D + R E+ + E E + +EEEE++ + E + E+
Sbjct: 539 -EKKTQEQEKKTWDQEEKMREEERMRER--------EKKMREEEEMMREQ---EEKMQEQ 586
Query: 130 AEQQRIRNEREKERQNRLAEERARR-EEEENRRKAEDEARKKKALSNMMHFGGYIQ---- 184
E+ R + E+ E++ ++ E+ + E+EE + E+E + ++ M +Q
Sbjct: 587 EEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEE 646
Query: 185 ----------------KAQTERKSGKRQTEREKKKKILAERRKVLAIDHLNEDQLREKAK 228
+ Q E+ G+ + RE+++K+ + K+ E+++R + +
Sbjct: 647 KMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKM----REQEEKMRGQEE 702
Query: 229 ELWQSIYNLEAEKFDLQEKFKQQKYEINVLRNRINDNQKVSKTR 272
++W + EK QE+ + E+ RI D ++ + R
Sbjct: 703 KMWG-----QEEKMWGQEEKMWGQEEMREKEERIRDQKEKMQER 741
Score = 51.2 bits (121), Expect = 1e-06
Identities = 55/276 (19%), Positives = 124/276 (44%), Gaps = 31/276 (11%)
Query: 4 IEEVVEEYEEEEQE------EQEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDGPMEE 57
IEE+ +E + E EE +++AE + + +E+ E + KE ++
Sbjct: 161 IEELTKERDALSLELYRNTITNEELKKKNAELQEKLRLAESEKSEIQLNVKE-----LKR 215
Query: 58 SKPKPRSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHFENRKKEEEELVS 117
+ + +P + + + R E++L E + I E ++EE L
Sbjct: 216 KLERAKFLLPQVQTNTLQE---------EMWRQEEELREQEKKIRKQEEKMWRQEERLRE 266
Query: 118 LKDRIERRRAERAEQQRIRNEREK---ERQNRLAEERARREEEENRRKAEDEARKKKALS 174
+ ++ + + Q++ E+EK E++ L E++ RE+EE ++ E++ +++
Sbjct: 267 QEGKMREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQE--- 323
Query: 175 NMMHFGGYIQKAQTERKSGKRQTEREKKKKILAERRKVLAIDHL---NEDQLREKAKELW 231
M Q ER + + RE+++K+ + ++ D E+++RE+ K +W
Sbjct: 324 EKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEK-MW 382
Query: 232 QSIYNLEAEKFDLQEKFKQQKYEINVLRNRINDNQK 267
+ ++ E+ ++E+ K+ + E +R + QK
Sbjct: 383 EQEEKMQEEE-RIREREKKMREEEETMREQEEKMQK 417
Score = 50.8 bits (120), Expect = 1e-06
Identities = 48/212 (22%), Positives = 104/212 (49%), Gaps = 11/212 (5%)
Query: 5 EEVVEEYEEEEQEEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDGPMEESKPKPRS 64
E++ EE + +EQE++ EE E E + EEEE +E E+ M+E + K R
Sbjct: 534 EKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEE-KMQEQEEKMRE 592
Query: 65 FMPNL--VPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHFENRKK--EEEELVSLKD 120
+ K+ + E ++ + +++ +++Q E +E +K E+EE + ++
Sbjct: 593 QEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQE 652
Query: 121 RIERRRAERAEQQRIRNEREKERQNRLAEERARREEEENRRKAEDEARKKKALSNMMHFG 180
R + E+ +Q + + ++E+ R EE+ + +EE+ R + E +++ + +G
Sbjct: 653 EKMREQEEKMREQEEKMQGQEEKM-REQEEKMQGQEEKMREQEEKMRGQEEKM-----WG 706
Query: 181 GYIQKAQTERKSGKRQTEREKKKKILAERRKV 212
+ E K ++ REK+++I ++ K+
Sbjct: 707 QEEKMWGQEEKMWGQEEMREKEERIRDQKEKM 738
Score = 50.4 bits (119), Expect = 2e-06
Identities = 47/200 (23%), Positives = 89/200 (44%), Gaps = 25/200 (12%)
Query: 1 MSDIEEVVEEYEEEE-QEEQEEAAEEDAEAEAETEETRAEEDE---EEEEAKEAEDGPME 56
M + EE + E EE+ ++E+E+ +E E E EE E++E E+EE ++ M
Sbjct: 604 MQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMR 663
Query: 57 ESKPKPRSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHFENRKKEEEELV 116
E + K + E++ + + E+ + E + + E +EE++
Sbjct: 664 EQEEKMQG-----------QEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKMW 712
Query: 117 SLKDRIERRRAERAEQQRIRNEREKERQNRLAEERARREEEENRRKAEDEARKKKALSNM 176
++++ + R +++RIR+++EK ++ R E R +E K L NM
Sbjct: 713 GQEEKMWGQEEMREKEERIRDQKEKMQE---------RLPEHEERCSEPCLPPSKVLCNM 763
Query: 177 MHFGGYIQKAQTERKSGKRQ 196
H G ++ A E G Q
Sbjct: 764 SHTGS-VEPAGGEAGEGSPQ 782
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 67.0 bits (162), Expect = 2e-11
Identities = 57/265 (21%), Positives = 130/265 (49%), Gaps = 32/265 (12%)
Query: 3 DIEEVVEEYEEEEQEEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDGPMEESKPKP 62
++EE + E E+ ++E++ EE + + +E A+ +EE+ +E E+ E+ +
Sbjct: 442 ELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMW 501
Query: 63 RSFMPNLVPPKIPDGE-RVDFDDIHRK-----------RMEKDLNELQALIEAHFENRKK 110
R KI + E R + +++ R+ R ++ ++E + I E +
Sbjct: 502 RQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWR 561
Query: 111 EEEELVSLKDRI-ERRRAERAEQQRIRNEREKERQNRLAEERARREEEENRRKAEDEARK 169
+EE++ +++I E+ ++++IR + EK R+ EE+ R +EE + + E +
Sbjct: 562 QEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQ---EEKIREQEEMTQEQEEKMGEQ 618
Query: 170 KKALSNMMHFGGYIQKAQTERKSGKRQTE--REKKKKILAERRKVLAIDHLNEDQLREKA 227
++ + +K Q + + +RQ E RE++KKI + K+ E+ ++E+
Sbjct: 619 EEKMCEQE------EKMQEQEEKMRRQEEKIREQEKKIREQEEKI----REQEEMMQEQE 668
Query: 228 KELWQSIYNLEAEKFDLQEKFKQQK 252
+++W+ E + + +EK ++Q+
Sbjct: 669 EKMWEQ----EEKMCEQEEKMQEQE 689
Score = 62.8 bits (151), Expect = 3e-10
Identities = 52/281 (18%), Positives = 123/281 (43%), Gaps = 73/281 (25%)
Query: 5 EEVVEEYEEEEQEEQEEAAEEDAEAEAETEETRAEED---EEEEEAKEAEDGPMEESKPK 61
EE ++E+EE+ QE++E+ E++ + + E+ R +E+ E+EE+ + E+ E+
Sbjct: 367 EEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKE--- 423
Query: 62 PRSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHFENRKKEEEELVSLKDR 121
E +++EE + +++
Sbjct: 424 --------------------------------------------EKMRRQEEMMWEKEEK 439
Query: 122 IERRRAERAEQQRIRNEREKERQNRLAEERARREEEE------NRRKAEDEARKKKALSN 175
I + EQ++IR + EK ++ E+ +R+E+E + E E + ++
Sbjct: 440 IRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEK 499
Query: 176 MMHFGGYIQKAQTERKSGKRQTERE---------KKKKILAERRKVLAIDHLNEDQLREK 226
M I + + R+ KRQ + E ++++I ++ K+ H E+++R++
Sbjct: 500 MWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKI----HEQEEKIRKQ 555
Query: 227 AKELWQSIYNLEAEKFDLQEKFKQQKYEINVLRNRINDNQK 267
+++W+ E + D +EK ++Q+ ++ +I + ++
Sbjct: 556 EEKMWRQ----EEKMHDQEEKIREQEEKVWRQEEKIREQEE 592
Score = 58.2 bits (139), Expect = 8e-09
Identities = 58/294 (19%), Positives = 140/294 (47%), Gaps = 28/294 (9%)
Query: 4 IEEVVEEYEEEEQE------EQEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDGPMEE 57
IEE+ +E + E EE E++A+ + + + +E+ E + KE ++
Sbjct: 256 IEELTKERDALSLELYRNTITDEELKEKNAKLQEKLQLVESEKSEIQLNVKE-----LKR 310
Query: 58 SKPKPRSFMPNLVPPKIPDGERVDFDDIHRK-RMEKDLNEL-QALIEAHFENRKKEEEEL 115
+ + +P D + + K + + + NEL L + E ++EE++
Sbjct: 311 KLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKI 370
Query: 116 VSLKDRIERRRAE-RAEQQRIRNEREKERQNRLA----EERARREEE------ENRRKAE 164
+++I+ + + R ++++IR + EK R+ EE+ RR+EE E R+ E
Sbjct: 371 QEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQE 430
Query: 165 D----EARKKKALSNMMHFGGYIQKAQTERKSGKRQTEREKKKKILAERRKVLAIDHLNE 220
+ + K + L MH I++ + +R+ ++ E+EK+++ A+ + E
Sbjct: 431 EMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQE 490
Query: 221 DQLREKAKELWQSIYNLEAEKFDLQEKFKQQKYEINVLRNRINDNQKVSKTRGK 274
+++RE+ +++W+ + ++ +E+ +Q++ E+ +I + +++ + + K
Sbjct: 491 EKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEK 544
Score = 52.0 bits (123), Expect = 6e-07
Identities = 41/172 (23%), Positives = 81/172 (47%), Gaps = 24/172 (13%)
Query: 1 MSDIEEVVEEYEE------EEQEEQEEAAEEDAEAEAETEETRAEEDE---EEEEAKEAE 51
M D EE + E EE E+ EQEE E E E EE E++E E+EE +
Sbjct: 566 MHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQ 625
Query: 52 DGPMEESKPKPRSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHFENRKKE 111
+ M+E + K R E++ + + E+ + E + +++ E ++
Sbjct: 626 EEKMQEQEEKMRR-----------QEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQ 674
Query: 112 EEELVSLKDRIERRRAERAEQQRIRNEREKERQNRLAEERARREEEENRRKA 163
EE++ +++++ E+ E+ R + E+ E++ RL ++ + +E + +A
Sbjct: 675 EEKMCEQEEKMQ----EQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLEA 722
Score = 48.5 bits (114), Expect = 6e-06
Identities = 43/223 (19%), Positives = 106/223 (47%), Gaps = 27/223 (12%)
Query: 5 EEVVEEYEEEEQEE---QEEAAEEDAEAEAETEETRAEEDE--EEEEAKEAEDGPMEESK 59
E++ EE + +EQEE QEE E E + E+ +E++ ++EE ++ M + +
Sbjct: 511 EKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQE 570
Query: 60 PKPRSFMPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHFENRKKEEEELVSLK 119
K R + + E++ + + E+ + E + + + E ++EE++ +
Sbjct: 571 EKIREQEEKVWRQE----EKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQE 626
Query: 120 DRIERRRAE-RAEQQRIRNE----REKERQNRLAEERARREEEENRRKAEDEARKKKALS 174
++++ + + R ++++IR + RE+E + R EE + +EE+ + E ++
Sbjct: 627 EKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQE---- 682
Query: 175 NMMHFGGYIQKAQTERKSGKRQTEREKKKKILAERRKVLAIDH 217
+K Q + + +RQ E+ ++++ +++ +H
Sbjct: 683 ---------EKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEH 716
Score = 47.8 bits (112), Expect = 1e-05
Identities = 32/158 (20%), Positives = 71/158 (44%), Gaps = 4/158 (2%)
Query: 12 EEEEQEEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDGPMEESKPKPRSFMPNLVP 71
+EE+ +QEE E E EE + E EE+ +E + EE + M
Sbjct: 562 QEEKMHDQEEKIREQEEKVWRQEE-KIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEE 620
Query: 72 PKIPDGERVDFDDIHRKRMEKDLNELQALIEAHFENRKKEEEELVSLKDRI---ERRRAE 128
E++ + +R E+ + E + I E +++EE + ++++ E + E
Sbjct: 621 KMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCE 680
Query: 129 RAEQQRIRNEREKERQNRLAEERARREEEENRRKAEDE 166
+ E+ + + E+ + ++ ++ E+ R ++E + + E
Sbjct: 681 QEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQE 718
Score = 33.1 bits (74), Expect = 0.28
Identities = 29/145 (20%), Positives = 70/145 (48%), Gaps = 14/145 (9%)
Query: 123 ERRRAERAEQQRIRNEREKERQN-------RLAEERARREEEENRRKAEDEARKK-KALS 174
+ ++A Q+ +R E E + + + A + ++ E EAR L
Sbjct: 170 DEQKASHQHQEALRRELEAQVHTIRILTCQKTELQMALYYSQHAVKQLEGEARDLISRLH 229
Query: 175 NMMHFGGYIQKAQTERKSGKRQTEREKKKKILAERRKVLAID----HLNEDQLREKAKEL 230
+ F G +++A + + K++ +R ++ L + R L+++ + +++L+EK +L
Sbjct: 230 DSWKFAGELEQALSAVATQKKKADRYIEE--LTKERDALSLELYRNTITDEELKEKNAKL 287
Query: 231 WQSIYNLEAEKFDLQEKFKQQKYEI 255
+ + +E+EK ++Q K+ K ++
Sbjct: 288 QEKLQLVESEKSEIQLNVKELKRKL 312
>gi|155030232 proline, glutamic acid and leucine rich protein 1
[Homo sapiens]
Length = 1130
Score = 66.6 bits (161), Expect = 2e-11
Identities = 40/79 (50%), Positives = 46/79 (58%), Gaps = 8/79 (10%)
Query: 5 EEVVEEYEEEEQEEQEEAAEEDAEAEAETEETRAEED-EEEEEAKEAED-------GPME 56
EE EEY EEE+EE+EE EE E E E EE EED EEEEE +E ED G +E
Sbjct: 914 EEDEEEYFEEEEEEEEEFEEEFEEEEGELEEEEEEEDEEEEEELEEVEDLEFGTAGGEVE 973
Query: 57 ESKPKPRSFMPNLVPPKIP 75
E P P + P L PP+ P
Sbjct: 974 EGAPPPPTLPPALPPPESP 992
Score = 45.8 bits (107), Expect = 4e-05
Identities = 40/151 (26%), Positives = 63/151 (41%), Gaps = 13/151 (8%)
Query: 7 VVEEYEEEEQEEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDGPMEESKPKPRSFM 66
V+ +E+EE+EE EE+ E E E EE EE+E+EEE E E+ EE + F
Sbjct: 880 VININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEE---EEEEEFEEEF- 935
Query: 67 PNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHFENRKKEEEELVSLKDRIERRR 126
+ E + ++ + E++ EL+ + + F E EE +
Sbjct: 936 ---------EEEEGELEEEEEEEDEEEEEELEEVEDLEFGTAGGEVEEGAPPPPTLPPAL 986
Query: 127 AERAEQQRIRNEREKERQNRLAEERARREEE 157
+++ E E E L E EEE
Sbjct: 987 PPPESPPKVQPEPEPEPGLLLEVEEPGTEEE 1017
Score = 39.3 bits (90), Expect = 0.004
Identities = 36/136 (26%), Positives = 49/136 (36%), Gaps = 18/136 (13%)
Query: 42 EEEEEAKEAEDGPMEESKPKPRSFM-------PNLVPPKIPDGERVDFDDIHRKRMEKDL 94
+EE E A GP+ P P P LVP P G +E+DL
Sbjct: 826 KEEPEELPAAPGPLPPPPPPPPPVPGPVTLPPPQLVPEGTPGGGGPP-------ALEEDL 878
Query: 95 NELQALI----EAHFENRKKEEEELVSLKDRIERRRAERAEQQRIRNEREKERQNRLAEE 150
+ E E ++EEEE ++ E + E E E+E + EE
Sbjct: 879 TVININSSDEEEEEEEEEEEEEEEEEEEEEDFEEEEEDEEEYFEEEEEEEEEFEEEFEEE 938
Query: 151 RARREEEENRRKAEDE 166
EEEE E+E
Sbjct: 939 EGELEEEEEEEDEEEE 954
Score = 34.3 bits (77), Expect = 0.13
Identities = 20/61 (32%), Positives = 34/61 (55%), Gaps = 3/61 (4%)
Query: 4 IEEVVEEYEEEEQEEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEAE--DGPMEESKPK 61
+EE E+ ++ Q E AEE+ E E E E + E+++++ A A+ D P ++ KP
Sbjct: 1065 LEEETEDGSDKVQPPPETPAEEEMETETEAEALQ-EKEQDDTAAMLADFIDCPPDDEKPP 1123
Query: 62 P 62
P
Sbjct: 1124 P 1124
Score = 33.5 bits (75), Expect = 0.22
Identities = 32/121 (26%), Positives = 48/121 (39%), Gaps = 38/121 (31%)
Query: 22 AAEEDAEAEAETEETRAEEDEEEEEAKEAEDGPMEESKPKPRSFMPNLVPPKIPDGERVD 81
A EED EE+EEEEE +E E+ EE D
Sbjct: 873 ALEEDLTVININSSDEEEEEEEEEEEEEEEEEEEEE-----------------------D 909
Query: 82 FDDIHRKRMEKDLNELQALIEAHFENRKKEEEELVSLKDRIERRRAERAEQQRIRNEREK 141
F+ E++ +E E +FE ++EEEE ++ E E E++ +E E+
Sbjct: 910 FE-------EEEEDE-----EEYFEEEEEEEEE---FEEEFEEEEGELEEEEEEEDEEEE 954
Query: 142 E 142
E
Sbjct: 955 E 955
>gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo
sapiens]
Length = 1293
Score = 66.2 bits (160), Expect = 3e-11
Identities = 64/283 (22%), Positives = 128/283 (45%), Gaps = 33/283 (11%)
Query: 6 EVVEEYEEEEQEEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDGPMEESKPKPRSF 65
E+ + EEEE++ QEE + E +E + EEEE A+ ++ + + + +
Sbjct: 739 EMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIAL 798
Query: 66 MPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHFENRKKEEEELVSLKDRIERR 125
R++ E++ + Q E R++EEEE ++ + ++
Sbjct: 799 ---------------------RRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQ 837
Query: 126 RAERAEQQRIRNEREKERQNRLAEERARREEEENRRKAEDEARKKKALSNMMHFGGYIQK 185
E A+ R E+E Q RL E R R EEE R + E+E RK+K L + + +
Sbjct: 838 EEEAAKWAR----EEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELE--VQRQKELMR 891
Query: 186 AQTERKSGKRQTEREKKKKILAERRKVLAI---DHLNEDQLREKAKELWQSIYNLEAEK- 241
+ +++ R+ +++++++ LA+ + + N + +A I LE E+
Sbjct: 892 QRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERE 951
Query: 242 FDLQEKFKQQKYEI--NVLRNRINDNQKVSKTRGKAKVTGRWK 282
L+E+ ++Q+ E+ + + + QK+S +K +G K
Sbjct: 952 RQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTK 994
Score = 58.2 bits (139), Expect = 8e-09
Identities = 44/162 (27%), Positives = 85/162 (52%), Gaps = 7/162 (4%)
Query: 94 LNELQALIEAHFENRKKEEEELVSLKDRIERRRAERAEQQRIRNEREKERQNRLAEERAR 153
L +LQ L +A K E+E + R +R ER Q+ +R ++E+ + + EER R
Sbjct: 717 LEQLQQLEKA---KAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKR 773
Query: 154 REEEE-NRRKAEDEARKKKALSNMMHFGGYIQKAQTERKSGKRQTEREKKKKILAERRKV 212
REEEE RRK E+ R+++ + ++ Q + ++ +R ER ++++ ERRK
Sbjct: 774 REEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEE---ERRKQ 830
Query: 213 LAIDHLNEDQLREKAKELWQSIYNLEAEKFDLQEKFKQQKYE 254
+ E++ + A+E ++ LE + ++E+ + ++E
Sbjct: 831 EELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHE 872
Score = 57.8 bits (138), Expect = 1e-08
Identities = 58/266 (21%), Positives = 119/266 (44%), Gaps = 42/266 (15%)
Query: 12 EEEEQEEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDGPMEESKPKPRSFMPNLVP 71
EEEE+++QEEA E E EE R +E+ ++ +EA EE + + R
Sbjct: 803 EEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRL------- 855
Query: 72 PKIPDGERVDFDDIHRKRMEKDLNELQALIEAHFENRKKEEEELVSLKDRIERRRAERAE 131
+ +R RME++ L+ H E +K +E V + + R+R + +
Sbjct: 856 ------------EENRLRMEEEAARLR-----HEEEERKRKELEVQRQKELMRQRQQ--Q 896
Query: 132 QQRIRNEREKERQNRLAEERARREEEENRRKAEDEARKKKALSNMMHFGGYIQKAQTERK 191
Q+ +R +++++Q +LA+ + ++ + + LS IQK + ER+
Sbjct: 897 QEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSL-----AEIQKLEEERE 951
Query: 192 SGKRQTEREKKKKIL--------AERRKVLAIDHLNEDQLREKAKELWQSIYNLEAEKFD 243
R+ +R ++++++ +++K+ ++++ K+ I EA +
Sbjct: 952 RQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKS---LLEIQQEEARQMQ 1008
Query: 244 LQEKFKQQKYEINVLRNRINDNQKVS 269
Q++ +QQ + N RN + N S
Sbjct: 1009 KQQQQQQQHQQPNRARNNTHSNLHTS 1034
Score = 52.8 bits (125), Expect = 3e-07
Identities = 50/222 (22%), Positives = 106/222 (47%), Gaps = 29/222 (13%)
Query: 14 EEQEEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDGPMEESKPKPRSFMPNLVPPK 73
E+ ++ E+A E E E RA+ +EEE + +E EE + +
Sbjct: 718 EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQE--------- 768
Query: 74 IPDGERVDFDDIHRKRMEKDLNELQALIEAHFENRKKEEEELVSLKDRIERRRAERAEQQ 133
+ +R + +++ R++ E+ L + E R++ EEE ER++ E A ++
Sbjct: 769 -EERKRREEEELARRKQEEALRRQR---EQEIALRRQREEE--------ERQQQEEALRR 816
Query: 134 RIRNEREKERQNRLAEERARREEEENRRKAEDEARKKKALS----NMMHFGGYIQKAQTE 189
RE+E + R EE R++EEE + A +E ++ L M ++ + E
Sbjct: 817 LEERRREEEER-RKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEE 875
Query: 190 RKSGKRQTEREKKKKILAERRKVL-AIDHLNEDQLREKAKEL 230
RK +++ E +++K+++ +R++ A+ L + Q +++ ++
Sbjct: 876 RK--RKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQM 915
Score = 49.7 bits (117), Expect = 3e-06
Identities = 40/142 (28%), Positives = 73/142 (51%), Gaps = 13/142 (9%)
Query: 121 RIERRRAERAEQQRIRNEREKERQNRLA---EERARREEEENRRKAEDEARKKKALSNMM 177
++E+ R E AE + R E E++RQ L EE RR++EE R++ E+E ++ +
Sbjct: 730 KLEQERRE-AEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEAL 788
Query: 178 HFGGYIQKAQTERKSGKRQTEREKKKKILAERRKVLAIDHLNEDQLREKAKELWQSIYNL 237
+ A ++ + + ++E+ + L ERR+ E++ R K +EL +
Sbjct: 789 RRQREQEIALRRQREEEERQQQEEALRRLEERRR--------EEEERRKQEELLRK-QEE 839
Query: 238 EAEKFDLQEKFKQQKYEINVLR 259
EA K+ +E+ Q++ E N LR
Sbjct: 840 EAAKWAREEEEAQRRLEENRLR 861
Score = 28.1 bits (61), Expect = 9.0
Identities = 26/92 (28%), Positives = 36/92 (39%), Gaps = 25/92 (27%)
Query: 9 EEYEEEEQEEQEEAAEED--------------AEAEAETEETRAE-------EDEEEEEA 47
EE + E EEA E D EA ET +T + D + +EA
Sbjct: 326 EECSDSEGSHNEEAKEPDKTNKKEGEKTDRVGVEASEETPQTSSSSARPGTPSDHQSQEA 385
Query: 48 K--EAEDGPMEE--SKPKPRSFMPNLVPPKIP 75
E +D P E K + + M N +P K+P
Sbjct: 386 SQFERKDEPKTEQTEKAEEETRMENSLPAKVP 417
>gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sapiens]
Length = 1320
Score = 66.2 bits (160), Expect = 3e-11
Identities = 64/283 (22%), Positives = 128/283 (45%), Gaps = 33/283 (11%)
Query: 6 EVVEEYEEEEQEEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDGPMEESKPKPRSF 65
E+ + EEEE++ QEE + E +E + EEEE A+ ++ + + + +
Sbjct: 766 EMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIAL 825
Query: 66 MPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHFENRKKEEEELVSLKDRIERR 125
R++ E++ + Q E R++EEEE ++ + ++
Sbjct: 826 ---------------------RRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQ 864
Query: 126 RAERAEQQRIRNEREKERQNRLAEERARREEEENRRKAEDEARKKKALSNMMHFGGYIQK 185
E A+ R E+E Q RL E R R EEE R + E+E RK+K L + + +
Sbjct: 865 EEEAAKWAR----EEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELE--VQRQKELMR 918
Query: 186 AQTERKSGKRQTEREKKKKILAERRKVLAI---DHLNEDQLREKAKELWQSIYNLEAEK- 241
+ +++ R+ +++++++ LA+ + + N + +A I LE E+
Sbjct: 919 QRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERE 978
Query: 242 FDLQEKFKQQKYEI--NVLRNRINDNQKVSKTRGKAKVTGRWK 282
L+E+ ++Q+ E+ + + + QK+S +K +G K
Sbjct: 979 RQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTK 1021
Score = 58.2 bits (139), Expect = 8e-09
Identities = 44/162 (27%), Positives = 85/162 (52%), Gaps = 7/162 (4%)
Query: 94 LNELQALIEAHFENRKKEEEELVSLKDRIERRRAERAEQQRIRNEREKERQNRLAEERAR 153
L +LQ L +A K E+E + R +R ER Q+ +R ++E+ + + EER R
Sbjct: 744 LEQLQQLEKA---KAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKR 800
Query: 154 REEEE-NRRKAEDEARKKKALSNMMHFGGYIQKAQTERKSGKRQTEREKKKKILAERRKV 212
REEEE RRK E+ R+++ + ++ Q + ++ +R ER ++++ ERRK
Sbjct: 801 REEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEE---ERRKQ 857
Query: 213 LAIDHLNEDQLREKAKELWQSIYNLEAEKFDLQEKFKQQKYE 254
+ E++ + A+E ++ LE + ++E+ + ++E
Sbjct: 858 EELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHE 899
Score = 57.8 bits (138), Expect = 1e-08
Identities = 58/266 (21%), Positives = 119/266 (44%), Gaps = 42/266 (15%)
Query: 12 EEEEQEEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDGPMEESKPKPRSFMPNLVP 71
EEEE+++QEEA E E EE R +E+ ++ +EA EE + + R
Sbjct: 830 EEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRL------- 882
Query: 72 PKIPDGERVDFDDIHRKRMEKDLNELQALIEAHFENRKKEEEELVSLKDRIERRRAERAE 131
+ +R RME++ L+ H E +K +E V + + R+R + +
Sbjct: 883 ------------EENRLRMEEEAARLR-----HEEEERKRKELEVQRQKELMRQRQQ--Q 923
Query: 132 QQRIRNEREKERQNRLAEERARREEEENRRKAEDEARKKKALSNMMHFGGYIQKAQTERK 191
Q+ +R +++++Q +LA+ + ++ + + LS IQK + ER+
Sbjct: 924 QEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSL-----AEIQKLEEERE 978
Query: 192 SGKRQTEREKKKKIL--------AERRKVLAIDHLNEDQLREKAKELWQSIYNLEAEKFD 243
R+ +R ++++++ +++K+ ++++ K+ I EA +
Sbjct: 979 RQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKS---LLEIQQEEARQMQ 1035
Query: 244 LQEKFKQQKYEINVLRNRINDNQKVS 269
Q++ +QQ + N RN + N S
Sbjct: 1036 KQQQQQQQHQQPNRARNNTHSNLHTS 1061
Score = 52.8 bits (125), Expect = 3e-07
Identities = 50/222 (22%), Positives = 106/222 (47%), Gaps = 29/222 (13%)
Query: 14 EEQEEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDGPMEESKPKPRSFMPNLVPPK 73
E+ ++ E+A E E E RA+ +EEE + +E EE + +
Sbjct: 745 EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQE--------- 795
Query: 74 IPDGERVDFDDIHRKRMEKDLNELQALIEAHFENRKKEEEELVSLKDRIERRRAERAEQQ 133
+ +R + +++ R++ E+ L + E R++ EEE ER++ E A ++
Sbjct: 796 -EERKRREEEELARRKQEEALRRQR---EQEIALRRQREEE--------ERQQQEEALRR 843
Query: 134 RIRNEREKERQNRLAEERARREEEENRRKAEDEARKKKALS----NMMHFGGYIQKAQTE 189
RE+E + R EE R++EEE + A +E ++ L M ++ + E
Sbjct: 844 LEERRREEEER-RKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEE 902
Query: 190 RKSGKRQTEREKKKKILAERRKVL-AIDHLNEDQLREKAKEL 230
RK +++ E +++K+++ +R++ A+ L + Q +++ ++
Sbjct: 903 RK--RKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQM 942
Score = 49.7 bits (117), Expect = 3e-06
Identities = 40/142 (28%), Positives = 73/142 (51%), Gaps = 13/142 (9%)
Query: 121 RIERRRAERAEQQRIRNEREKERQNRLA---EERARREEEENRRKAEDEARKKKALSNMM 177
++E+ R E AE + R E E++RQ L EE RR++EE R++ E+E ++ +
Sbjct: 757 KLEQERRE-AEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEAL 815
Query: 178 HFGGYIQKAQTERKSGKRQTEREKKKKILAERRKVLAIDHLNEDQLREKAKELWQSIYNL 237
+ A ++ + + ++E+ + L ERR+ E++ R K +EL +
Sbjct: 816 RRQREQEIALRRQREEEERQQQEEALRRLEERRR--------EEEERRKQEELLRK-QEE 866
Query: 238 EAEKFDLQEKFKQQKYEINVLR 259
EA K+ +E+ Q++ E N LR
Sbjct: 867 EAAKWAREEEEAQRRLEENRLR 888
>gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo sapiens]
Length = 1299
Score = 66.2 bits (160), Expect = 3e-11
Identities = 64/283 (22%), Positives = 128/283 (45%), Gaps = 33/283 (11%)
Query: 6 EVVEEYEEEEQEEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDGPMEESKPKPRSF 65
E+ + EEEE++ QEE + E +E + EEEE A+ ++ + + + +
Sbjct: 745 EMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIAL 804
Query: 66 MPNLVPPKIPDGERVDFDDIHRKRMEKDLNELQALIEAHFENRKKEEEELVSLKDRIERR 125
R++ E++ + Q E R++EEEE ++ + ++
Sbjct: 805 ---------------------RRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQ 843
Query: 126 RAERAEQQRIRNEREKERQNRLAEERARREEEENRRKAEDEARKKKALSNMMHFGGYIQK 185
E A+ R E+E Q RL E R R EEE R + E+E RK+K L + + +
Sbjct: 844 EEEAAKWAR----EEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELE--VQRQKELMR 897
Query: 186 AQTERKSGKRQTEREKKKKILAERRKVLAI---DHLNEDQLREKAKELWQSIYNLEAEK- 241
+ +++ R+ +++++++ LA+ + + N + +A I LE E+
Sbjct: 898 QRQQQQEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERE 957
Query: 242 FDLQEKFKQQKYEI--NVLRNRINDNQKVSKTRGKAKVTGRWK 282
L+E+ ++Q+ E+ + + + QK+S +K +G K
Sbjct: 958 RQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTK 1000
Score = 58.2 bits (139), Expect = 8e-09
Identities = 44/162 (27%), Positives = 85/162 (52%), Gaps = 7/162 (4%)
Query: 94 LNELQALIEAHFENRKKEEEELVSLKDRIERRRAERAEQQRIRNEREKERQNRLAEERAR 153
L +LQ L +A K E+E + R +R ER Q+ +R ++E+ + + EER R
Sbjct: 723 LEQLQQLEKA---KAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKR 779
Query: 154 REEEE-NRRKAEDEARKKKALSNMMHFGGYIQKAQTERKSGKRQTEREKKKKILAERRKV 212
REEEE RRK E+ R+++ + ++ Q + ++ +R ER ++++ ERRK
Sbjct: 780 REEEELARRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEE---ERRKQ 836
Query: 213 LAIDHLNEDQLREKAKELWQSIYNLEAEKFDLQEKFKQQKYE 254
+ E++ + A+E ++ LE + ++E+ + ++E
Sbjct: 837 EELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHE 878
Score = 57.8 bits (138), Expect = 1e-08
Identities = 58/266 (21%), Positives = 119/266 (44%), Gaps = 42/266 (15%)
Query: 12 EEEEQEEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDGPMEESKPKPRSFMPNLVP 71
EEEE+++QEEA E E EE R +E+ ++ +EA EE + + R
Sbjct: 809 EEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRL------- 861
Query: 72 PKIPDGERVDFDDIHRKRMEKDLNELQALIEAHFENRKKEEEELVSLKDRIERRRAERAE 131
+ +R RME++ L+ H E +K +E V + + R+R + +
Sbjct: 862 ------------EENRLRMEEEAARLR-----HEEEERKRKELEVQRQKELMRQRQQ--Q 902
Query: 132 QQRIRNEREKERQNRLAEERARREEEENRRKAEDEARKKKALSNMMHFGGYIQKAQTERK 191
Q+ +R +++++Q +LA+ + ++ + + LS IQK + ER+
Sbjct: 903 QEALRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSL-----AEIQKLEEERE 957
Query: 192 SGKRQTEREKKKKIL--------AERRKVLAIDHLNEDQLREKAKELWQSIYNLEAEKFD 243
R+ +R ++++++ +++K+ ++++ K+ I EA +
Sbjct: 958 RQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKS---LLEIQQEEARQMQ 1014
Query: 244 LQEKFKQQKYEINVLRNRINDNQKVS 269
Q++ +QQ + N RN + N S
Sbjct: 1015 KQQQQQQQHQQPNRARNNTHSNLHTS 1040
Score = 52.8 bits (125), Expect = 3e-07
Identities = 50/222 (22%), Positives = 106/222 (47%), Gaps = 29/222 (13%)
Query: 14 EEQEEQEEAAEEDAEAEAETEETRAEEDEEEEEAKEAEDGPMEESKPKPRSFMPNLVPPK 73
E+ ++ E+A E E E RA+ +EEE + +E EE + +
Sbjct: 724 EQLQQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQE--------- 774
Query: 74 IPDGERVDFDDIHRKRMEKDLNELQALIEAHFENRKKEEEELVSLKDRIERRRAERAEQQ 133
+ +R + +++ R++ E+ L + E R++ EEE ER++ E A ++
Sbjct: 775 -EERKRREEEELARRKQEEALRRQR---EQEIALRRQREEE--------ERQQQEEALRR 822
Query: 134 RIRNEREKERQNRLAEERARREEEENRRKAEDEARKKKALS----NMMHFGGYIQKAQTE 189
RE+E + R EE R++EEE + A +E ++ L M ++ + E
Sbjct: 823 LEERRREEEER-RKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEE 881
Query: 190 RKSGKRQTEREKKKKILAERRKVL-AIDHLNEDQLREKAKEL 230
RK +++ E +++K+++ +R++ A+ L + Q +++ ++
Sbjct: 882 RK--RKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQM 921
Score = 49.7 bits (117), Expect = 3e-06
Identities = 40/142 (28%), Positives = 73/142 (51%), Gaps = 13/142 (9%)
Query: 121 RIERRRAERAEQQRIRNEREKERQNRLA---EERARREEEENRRKAEDEARKKKALSNMM 177
++E+ R E AE + R E E++RQ L EE RR++EE R++ E+E ++ +
Sbjct: 736 KLEQERRE-AEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEAL 794
Query: 178 HFGGYIQKAQTERKSGKRQTEREKKKKILAERRKVLAIDHLNEDQLREKAKELWQSIYNL 237
+ A ++ + + ++E+ + L ERR+ E++ R K +EL +
Sbjct: 795 RRQREQEIALRRQREEEERQQQEEALRRLEERRR--------EEEERRKQEELLRK-QEE 845
Query: 238 EAEKFDLQEKFKQQKYEINVLR 259
EA K+ +E+ Q++ E N LR
Sbjct: 846 EAAKWAREEEEAQRRLEENRLR 867
Score = 28.1 bits (61), Expect = 9.0
Identities = 26/92 (28%), Positives = 36/92 (39%), Gaps = 25/92 (27%)
Query: 9 EEYEEEEQEEQEEAAEED--------------AEAEAETEETRAE-------EDEEEEEA 47
EE + E EEA E D EA ET +T + D + +EA
Sbjct: 332 EECSDSEGSHNEEAKEPDKTNKKEGEKTDRVGVEASEETPQTSSSSARPGTPSDHQSQEA 391
Query: 48 K--EAEDGPMEE--SKPKPRSFMPNLVPPKIP 75
E +D P E K + + M N +P K+P
Sbjct: 392 SQFERKDEPKTEQTEKAEEETRMENSLPAKVP 423
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.305 0.124 0.324
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,037,878
Number of Sequences: 37866
Number of extensions: 630409
Number of successful extensions: 44392
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1359
Number of HSP's successfully gapped in prelim test: 1115
Number of HSP's that attempted gapping in prelim test: 7682
Number of HSP's gapped (non-prelim): 14645
length of query: 282
length of database: 18,247,518
effective HSP length: 101
effective length of query: 181
effective length of database: 14,423,052
effective search space: 2610572412
effective search space used: 2610572412
T: 11
A: 40
X1: 16 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.9 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.