Guide to the Human Genome
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Search of human proteins with 4759184

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4759184 syntaxin 3 [Homo sapiens]
         (289 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4759184 syntaxin 3 [Homo sapiens]                                  550   e-157
gi|37577162 syntaxin 2 isoform 2 [Homo sapiens]                       350   1e-96
gi|4759182 syntaxin 1A (brain) [Homo sapiens]                         346   2e-95
gi|37577287 syntaxin 2 isoform 1 [Homo sapiens]                       343   1e-94
gi|16418379 syntaxin 1B [Homo sapiens]                                327   6e-90
gi|20149560 syntaxin 4 [Homo sapiens]                                 213   2e-55
gi|33667038 syntaxin 11 [Homo sapiens]                                144   9e-35
gi|49258196 syntaxin 19 [Homo sapiens]                                141   6e-34
gi|28933465 syntaxin 12 [Homo sapiens]                                 97   1e-20
gi|170932494 syntaxin 7 [Homo sapiens]                                 97   2e-20
gi|34447229 syntaxin 16 isoform b [Homo sapiens]                       82   4e-16
gi|47778943 syntaxin 16 isoform a [Homo sapiens]                       80   3e-15
gi|198041692 syntaxin 16 isoform d [Homo sapiens]                      80   3e-15
gi|198041688 syntaxin 16 isoform c [Homo sapiens]                      80   3e-15
gi|223972648 t-SNARE domain containing 1 [Homo sapiens]                53   4e-07
gi|94400932 syntaxin 5 [Homo sapiens]                                  48   1e-05
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]    46   3e-05
gi|38348356 testis expressed 9 [Homo sapiens]                          46   3e-05
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]     45   7e-05
gi|64085252 hypothetical protein LOC145508 [Homo sapiens]              45   1e-04
gi|4507285 syntaxin 10 [Homo sapiens]                                  44   2e-04
gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens]               42   5e-04
gi|110815815 centlein isoform 1 [Homo sapiens]                         42   5e-04
gi|167555106 centlein isoform 2 [Homo sapiens]                         42   5e-04
gi|4502443 dystonin isoform 1e precursor [Homo sapiens]                42   6e-04
gi|114155142 nuclear pore complex-associated protein TPR [Homo s...    42   8e-04
gi|31982906 cingulin-like 1 [Homo sapiens]                             42   8e-04
gi|90652855 EF-hand calcium binding domain 5 isoform a [Homo sap...    41   0.001
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho...    40   0.002
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho...    40   0.002

>gi|4759184 syntaxin 3 [Homo sapiens]
          Length = 289

 Score =  550 bits (1416), Expect = e-157
 Identities = 289/289 (100%), Positives = 289/289 (100%)

Query: 1   MKDRLEQLKAKQLTQDDDTDAVEIAIDNTAFMDEFFSEIEETRLNIDKISEHVEEAKKLY 60
           MKDRLEQLKAKQLTQDDDTDAVEIAIDNTAFMDEFFSEIEETRLNIDKISEHVEEAKKLY
Sbjct: 1   MKDRLEQLKAKQLTQDDDTDAVEIAIDNTAFMDEFFSEIEETRLNIDKISEHVEEAKKLY 60

Query: 61  SIILSAPIPEPKTKDDLEQLTTEIKKRANNVRNKLKSMEKHIEEDEVRSSADLRIRKSQH 120
           SIILSAPIPEPKTKDDLEQLTTEIKKRANNVRNKLKSMEKHIEEDEVRSSADLRIRKSQH
Sbjct: 61  SIILSAPIPEPKTKDDLEQLTTEIKKRANNVRNKLKSMEKHIEEDEVRSSADLRIRKSQH 120

Query: 121 SVLSRKFVEVMTKYNEAQVDFRERSKGRIQRQLEITGKKTTDEELEEMLESGNPAIFTSG 180
           SVLSRKFVEVMTKYNEAQVDFRERSKGRIQRQLEITGKKTTDEELEEMLESGNPAIFTSG
Sbjct: 121 SVLSRKFVEVMTKYNEAQVDFRERSKGRIQRQLEITGKKTTDEELEEMLESGNPAIFTSG 180

Query: 181 IIDSQISKQALSEIEGRHKDIVRLESSIKELHDMFMDIAMLVENQGEMLDNIELNVMHTV 240
           IIDSQISKQALSEIEGRHKDIVRLESSIKELHDMFMDIAMLVENQGEMLDNIELNVMHTV
Sbjct: 181 IIDSQISKQALSEIEGRHKDIVRLESSIKELHDMFMDIAMLVENQGEMLDNIELNVMHTV 240

Query: 241 DHVEKARDETKKAVKYQSQARKKLIIIIVLVVVLLGILALIIGLSVGLN 289
           DHVEKARDETKKAVKYQSQARKKLIIIIVLVVVLLGILALIIGLSVGLN
Sbjct: 241 DHVEKARDETKKAVKYQSQARKKLIIIIVLVVVLLGILALIIGLSVGLN 289


>gi|37577162 syntaxin 2 isoform 2 [Homo sapiens]
          Length = 288

 Score =  350 bits (897), Expect = 1e-96
 Identities = 186/290 (64%), Positives = 234/290 (80%), Gaps = 6/290 (2%)

Query: 1   MKDRLEQLKAKQLTQDDDTDAVEIAIDNTAFMDEFFSEIEETRLNIDKISEHVEEAKKLY 60
           M+DRL  L A +   D DT  V   ++   FMD+FF ++EE R +IDKI+++VEE KK +
Sbjct: 1   MRDRLPDLTACRKNDDGDTVVV---VEKDHFMDDFFHQVEEIRNSIDKITQYVEEVKKNH 57

Query: 61  SIILSAPIPEPKTKDDLEQLTTEIKKRANNVRNKLKSMEKHIEEDEV--RSSADLRIRKS 118
           SIILSAP PE K K++LE L  EIKK AN +R KLK++E+  ++DE   R+S DLRIR++
Sbjct: 58  SIILSAPNPEGKIKEELEDLNKEIKKTANKIRAKLKAIEQSFDQDESGNRTSVDLRIRRT 117

Query: 119 QHSVLSRKFVEVMTKYNEAQVDFRERSKGRIQRQLEITGKKTTDEELEEMLESGNPAIFT 178
           QHSVLSRKFVE M +YNEAQ  FRERSKGRIQRQLEITG+ TTD+ELEEMLESG P+IFT
Sbjct: 118 QHSVLSRKFVEAMAEYNEAQTLFRERSKGRIQRQLEITGRTTTDDELEEMLESGKPSIFT 177

Query: 179 SGII-DSQISKQALSEIEGRHKDIVRLESSIKELHDMFMDIAMLVENQGEMLDNIELNVM 237
           S II DSQI++QAL+EIE RHKDI++LE+SI+ELH+MFMD+AM VE QGEM++NIE NVM
Sbjct: 178 SDIISDSQITRQALNEIESRHKDIMKLETSIRELHEMFMDMAMFVETQGEMINNIERNVM 237

Query: 238 HTVDHVEKARDETKKAVKYQSQARKKLIIIIVLVVVLLGILALIIGLSVG 287
           +  D+VE A++ETKKA+KYQS+AR+K  III + VVL+ I+ALIIGLSVG
Sbjct: 238 NATDYVEHAKEETKKAIKYQSKARRKKWIIIAVSVVLVAIIALIIGLSVG 287


>gi|4759182 syntaxin 1A (brain) [Homo sapiens]
          Length = 288

 Score =  346 bits (887), Expect = 2e-95
 Identities = 181/286 (63%), Positives = 231/286 (80%), Gaps = 5/286 (1%)

Query: 1   MKDRLEQLKAKQLTQDDDTDAVEIAIDNTAFMDEFFSEIEETRLNIDKISEHVEEAKKLY 60
           MKDR ++L+  +    DD D V + +D   FMDEFF ++EE R  IDKI+E+VEE K+ +
Sbjct: 1   MKDRTQELRTAK--DSDDDDDVAVTVDRDRFMDEFFEQVEEIRGFIDKIAENVEEVKRKH 58

Query: 61  SIILSAPIPEPKTKDDLEQLTTEIKKRANNVRNKLKSMEKHIEEDEV--RSSADLRIRKS 118
           S IL++P P+ KTK++LE+L ++IKK AN VR+KLKS+E+ IE++E   RSSADLRIRK+
Sbjct: 59  SAILASPNPDEKTKEELEELMSDIKKTANKVRSKLKSIEQSIEQEEGLNRSSADLRIRKT 118

Query: 119 QHSVLSRKFVEVMTKYNEAQVDFRERSKGRIQRQLEITGKKTTDEELEEMLESGNPAIFT 178
           QHS LSRKFVEVM++YN  Q D+RER KGRIQRQLEITG+ TT EELE+MLESGNPAIF 
Sbjct: 119 QHSTLSRKFVEVMSEYNATQSDYRERCKGRIQRQLEITGRTTTSEELEDMLESGNPAIFA 178

Query: 179 SGII-DSQISKQALSEIEGRHKDIVRLESSIKELHDMFMDIAMLVENQGEMLDNIELNVM 237
           SGII DS ISKQALSEIE RH +I++LE+SI+ELHDMFMD+AMLVE+QGEM+D IE NV 
Sbjct: 179 SGIIMDSSISKQALSEIETRHSEIIKLENSIRELHDMFMDMAMLVESQGEMIDRIEYNVE 238

Query: 238 HTVDHVEKARDETKKAVKYQSQARKKLIIIIVLVVVLLGILALIIG 283
           H VD+VE+A  +TKKAVKYQS+AR+K I+II+  V+L  ++A  +G
Sbjct: 239 HAVDYVERAVSDTKKAVKYQSKARRKKIMIIICCVILGIVIASTVG 284


>gi|37577287 syntaxin 2 isoform 1 [Homo sapiens]
          Length = 287

 Score =  343 bits (880), Expect = 1e-94
 Identities = 180/289 (62%), Positives = 232/289 (80%), Gaps = 6/289 (2%)

Query: 1   MKDRLEQLKAKQLTQDDDTDAVEIAIDNTAFMDEFFSEIEETRLNIDKISEHVEEAKKLY 60
           M+DRL  L A +   D DT  V   ++   FMD+FF ++EE R +IDKI+++VEE KK +
Sbjct: 1   MRDRLPDLTACRKNDDGDTVVV---VEKDHFMDDFFHQVEEIRNSIDKITQYVEEVKKNH 57

Query: 61  SIILSAPIPEPKTKDDLEQLTTEIKKRANNVRNKLKSMEKHIEEDEV--RSSADLRIRKS 118
           SIILSAP PE K K++LE L  EIKK AN +R KLK++E+  ++DE   R+S DLRIR++
Sbjct: 58  SIILSAPNPEGKIKEELEDLNKEIKKTANKIRAKLKAIEQSFDQDESGNRTSVDLRIRRT 117

Query: 119 QHSVLSRKFVEVMTKYNEAQVDFRERSKGRIQRQLEITGKKTTDEELEEMLESGNPAIFT 178
           QHSVLSRKFVE M +YNEAQ  FRERSKGRIQRQLEITG+ TTD+ELEEMLESG P+IFT
Sbjct: 118 QHSVLSRKFVEAMAEYNEAQTLFRERSKGRIQRQLEITGRTTTDDELEEMLESGKPSIFT 177

Query: 179 SGII-DSQISKQALSEIEGRHKDIVRLESSIKELHDMFMDIAMLVENQGEMLDNIELNVM 237
           S II DSQI++QAL+EIE RHKDI++LE+SI+ELH+MFMD+AM VE QGEM++NIE NVM
Sbjct: 178 SDIISDSQITRQALNEIESRHKDIMKLETSIRELHEMFMDMAMFVETQGEMINNIERNVM 237

Query: 238 HTVDHVEKARDETKKAVKYQSQARKKLIIIIVLVVVLLGILALIIGLSV 286
           +  D+VE A++ETKKA+KYQS+AR+KL+ II+ V+VLL IL +I+  ++
Sbjct: 238 NATDYVEHAKEETKKAIKYQSKARRKLMFIIICVIVLLVILGIILATTL 286


>gi|16418379 syntaxin 1B [Homo sapiens]
          Length = 288

 Score =  327 bits (839), Expect = 6e-90
 Identities = 175/291 (60%), Positives = 230/291 (79%), Gaps = 6/291 (2%)

Query: 1   MKDRLEQLKAKQLTQDDDTDAVEIAIDNTAFMDEFFSEIEETRLNIDKISEHVEEAKKLY 60
           MKDR ++L++    +D D +   + +D   FMDEFF ++EE R  I+K+SE VE+ KK +
Sbjct: 1   MKDRTQELRS---AKDSDDEEEVVHVDRDHFMDEFFEQVEEIRGCIEKLSEDVEQVKKQH 57

Query: 61  SIILSAPIPEPKTKDDLEQLTTEIKKRANNVRNKLKSMEKHIEEDEV--RSSADLRIRKS 118
           S IL+AP P+ KTK +LE LT +IKK AN VR+KLK++E+ IE++E   RSSADLRIRK+
Sbjct: 58  SAILAAPNPDEKTKQELEDLTADIKKTANKVRSKLKAIEQSIEQEEGLNRSSADLRIRKT 117

Query: 119 QHSVLSRKFVEVMTKYNEAQVDFRERSKGRIQRQLEITGKKTTDEELEEMLESGNPAIFT 178
           QHS LSRKFVEVMT+YN  Q  +R+R K RIQRQLEITG+ TT+EELE+MLESG  AIFT
Sbjct: 118 QHSTLSRKFVEVMTEYNATQSKYRDRCKDRIQRQLEITGRTTTNEELEDMLESGKLAIFT 177

Query: 179 SGI-IDSQISKQALSEIEGRHKDIVRLESSIKELHDMFMDIAMLVENQGEMLDNIELNVM 237
             I +DSQ++KQAL+EIE RH +I++LE+SI+ELHDMF+D+AMLVE+QGEM+D IE NV 
Sbjct: 178 DDIKMDSQMTKQALNEIETRHNEIIKLETSIRELHDMFVDMAMLVESQGEMIDRIEYNVE 237

Query: 238 HTVDHVEKARDETKKAVKYQSQARKKLIIIIVLVVVLLGILALIIGLSVGL 288
           H+VD+VE+A  +TKKAVKYQS+AR+K I+II+  VVL  +LA  IG ++GL
Sbjct: 238 HSVDYVERAVSDTKKAVKYQSKARRKKIMIIICCVVLGVVLASSIGGTLGL 288


>gi|20149560 syntaxin 4 [Homo sapiens]
          Length = 297

 Score =  213 bits (542), Expect = 2e-55
 Identities = 120/295 (40%), Positives = 194/295 (65%), Gaps = 9/295 (3%)

Query: 1   MKDRLEQLKAKQLTQDD-DTDAVEIAID-NTAFM----DEFFSEIEETRLNIDKISEHVE 54
           M+DR  +L+    + D+ D + V + +   TA +    +EFF ++   R  I K+   V+
Sbjct: 1   MRDRTHELRQGDDSSDEEDKERVALVVHPGTARLGSPDEEFFHKVRTIRQTIVKLGNKVQ 60

Query: 55  EAKKLYSIILSAPIPEPKTKDDLEQLTTEIKKRANNVRNKLKSMEKHIEE-DEVRSSADL 113
           E +K    IL+ P+PE   K +L+ L  EIK+    +R +LK++E   EE DE  +S + 
Sbjct: 61  ELEKQQVTILATPLPEESMKQELQNLRDEIKQLGREIRLQLKAIEPQKEEADENYNSVNT 120

Query: 114 RIRKSQHSVLSRKFVEVMTKYNEAQVDFRERSKGRIQRQLEITGK-KTTDEELEEMLESG 172
           R+RK+QH VLS++FVE++ K N  Q ++RE++  RI+RQL+IT     +DEELE+ML+SG
Sbjct: 121 RMRKTQHGVLSQQFVELINKCNSMQSEYREKNVERIRRQLKITNAGMVSDEELEQMLDSG 180

Query: 173 NPAIFTSGII-DSQISKQALSEIEGRHKDIVRLESSIKELHDMFMDIAMLVENQGEMLDN 231
              +F S I+ D+Q+++QAL+EI  RH +I +LE SI+ELHD+F  +A  VE QGEM++ 
Sbjct: 181 QSEVFVSNILKDTQVTRQALNEISARHSEIQQLERSIRELHDIFTFLATEVEMQGEMINR 240

Query: 232 IELNVMHTVDHVEKARDETKKAVKYQSQARKKLIIIIVLVVVLLGILALIIGLSV 286
           IE N++ + D+VE+ ++  K A++ Q +ARKK ++I + V + + +LA+IIG++V
Sbjct: 241 IEKNILSSADYVERGQEHVKTALENQKKARKKKVLIAICVSITVVLLAVIIGVTV 295


>gi|33667038 syntaxin 11 [Homo sapiens]
          Length = 287

 Score =  144 bits (363), Expect = 9e-35
 Identities = 89/272 (32%), Positives = 158/272 (58%), Gaps = 13/272 (4%)

Query: 1   MKDRLEQLK--AKQLTQ-----DDDTDAV--EIAIDNTAFMDEFFSEIEETRLNIDKISE 51
           MKDRL +L   +KQ  Q     DD+ D+   +I  +    ++  + +I + +     +  
Sbjct: 1   MKDRLAELLDLSKQYDQQFPDGDDEFDSPHEDIVFETDHILESLYRDIRDIQDENQLLVA 60

Query: 52  HVEEAKKLYSIILSAPIPEPKTKDDLEQLTTEIKKRANNVRNKLKSMEKHIEEDEVRS-- 109
            V+   K  +  L++       K D   +   IK R   +  KL++M++  E  E +   
Sbjct: 61  DVKRLGKQNARFLTSMRRLSSIKRDTNSIAKAIKARGEVIHCKLRAMKELSEAAEAQHGP 120

Query: 110 -SADLRIRKSQHSVLSRKFVEVMTKYNEAQVDFRERSKGRIQRQLEITGKKTTDEELEEM 168
            SA  RI ++Q++ L+  F   M  YN+A++  R+  K RIQRQLEI GK+ + +++E+M
Sbjct: 121 HSAVARISRAQYNALTLTFQRAMHDYNQAEMKQRDNCKIRIQRQLEIMGKEVSGDQIEDM 180

Query: 169 LESGNPAIFTSGII-DSQISKQALSEIEGRHKDIVRLESSIKELHDMFMDIAMLVENQGE 227
            E G   +F+  ++ D + ++ AL+EIE RH++++RLES I+++H++F+ +A+LVE Q +
Sbjct: 181 FEQGKWDVFSENLLADVKGARAALNEIESRHRELLRLESRIRDVHELFLQMAVLVEKQAD 240

Query: 228 MLDNIELNVMHTVDHVEKARDETKKAVKYQSQ 259
            L+ IELNV  TVD+  +A+ + +KAV+Y+ +
Sbjct: 241 TLNVIELNVQKTVDYTGQAKAQVRKAVQYEEK 272


>gi|49258196 syntaxin 19 [Homo sapiens]
          Length = 294

 Score =  141 bits (356), Expect = 6e-34
 Identities = 86/278 (30%), Positives = 156/278 (56%), Gaps = 20/278 (7%)

Query: 1   MKDRLEQLKAK----QLTQDDDTDAVE-----------IAIDNTAFMDEFFSEIEETRLN 45
           MKDRL++LK +    +L++D      E           +  +     +    EI++ + +
Sbjct: 1   MKDRLQELKQRTKEIELSRDSHVSTTETEEQGVFLQQAVIYEREPVAERHLHEIQKLQES 60

Query: 46  IDKISEHVEEAKKLYSIILSAPIPEPKTKDDLEQLTTEIKKRANNVRNKLKSMEKHIEED 105
           I+ ++++V++  +    ++++       K +   +T EIK +A  +   L  + K +++ 
Sbjct: 61  INNLADNVQKFGQQQKSLVASMRRFSLLKRE-STITKEIKIQAEYINRSLNDLVKEVKKS 119

Query: 106 EVR---SSADLRIRKSQHSVLSRKFVEVMTKYNEAQVDFRERSKGRIQRQLEITGKKTTD 162
           EV    SS   RI KSQH+ + R F ++M  YN+     +E+ K  I RQLE+ GK+ ++
Sbjct: 120 EVENGPSSVVTRILKSQHAAMFRHFQQIMFIYNDTIAAKQEKCKTFILRQLEVAGKEMSE 179

Query: 163 EELEEMLESGNPAIFTSGII-DSQISKQALSEIEGRHKDIVRLESSIKELHDMFMDIAML 221
           E++ +ML  G   +F   ++ +  I+K  LSEIE RHK++V LE+ IK+L D+F+ I++L
Sbjct: 180 EDVNDMLHQGKWEVFNESLLTEINITKAQLSEIEQRHKELVNLENQIKDLRDLFIQISLL 239

Query: 222 VENQGEMLDNIELNVMHTVDHVEKARDETKKAVKYQSQ 259
           VE QGE ++NIE+ V  T ++V   +++   AVKY+ +
Sbjct: 240 VEEQGESINNIEMTVNSTKEYVNNTKEKFGLAVKYKKR 277


>gi|28933465 syntaxin 12 [Homo sapiens]
          Length = 276

 Score = 97.4 bits (241), Expect = 1e-20
 Identities = 73/258 (28%), Positives = 134/258 (51%), Gaps = 14/258 (5%)

Query: 34  EFFSEIEETRLNIDKISEHVEEAKKLYSIILSAPIPEPKTKDDLEQL---TTEIKKRANN 90
           +F S I+    NI +IS+   + K L S  L       K +++L+QL   T ++ K  N 
Sbjct: 21  DFSSIIQTCSGNIQRISQATAQIKNLMSQ-LGTKQDSSKLQENLQQLQHSTNQLAKETNE 79

Query: 91  VRNKLKSMEKHIEEDEVRSSADLRIRKSQHSVLSRKFVEVMTKYNEAQVDFRERSKGRIQ 150
           +  +L S+   +   E R     R++K +   L   F   +  +   Q    E+ K  I 
Sbjct: 80  LLKELGSLPLPLSTSEQRQQ---RLQKER---LMNDFSAALNNFQAVQRRVSEKEKESIA 133

Query: 151 RQLEITGKKTTDEELEEMLESGNPAIFTSGIIDSQ----ISKQALSEIEGRHKDIVRLES 206
           R    +     + + EE L S +     + +   +    I++Q L  I+ R   I +LE+
Sbjct: 134 RARAGSRLSAEERQREEQLVSFDSHEEWNQMQSQEDEVAITEQDLELIKERETAIRQLEA 193

Query: 207 SIKELHDMFMDIAMLVENQGEMLDNIELNVMHTVDHVEKARDETKKAVKYQSQARKKLII 266
            I +++ +F D+AM++ +QG+++D+IE NV  +  HVE+A ++ ++A  YQ ++RKK+ I
Sbjct: 194 DILDVNQIFKDLAMMIHDQGDLIDSIEANVESSEVHVERATEQLQRAAYYQKKSRKKMCI 253

Query: 267 IIVLVVVLLGILALIIGL 284
           +++++ V++ IL LII L
Sbjct: 254 LVLVLSVIILILGLIIWL 271


>gi|170932494 syntaxin 7 [Homo sapiens]
          Length = 261

 Score = 96.7 bits (239), Expect = 2e-20
 Identities = 63/241 (26%), Positives = 125/241 (51%), Gaps = 7/241 (2%)

Query: 48  KISEHVEEAKKLYSIILSAPIPEPKTKDDLEQLTTEIKKRANNVRNKLKSMEKHIEE--D 105
           +IS ++++  +  S+ +   + +  T  D  +L  +++++        K  +K+I+E   
Sbjct: 17  RISSNIQKITQC-SVEIQRTLNQLGTPQDSPELRQQLQQKQQYTNQLAKETDKYIKEFGS 75

Query: 106 EVRSSADLRIRKSQHSVLSRKFVEVMTKYNEAQVDFRERSK---GRIQRQLEITGKKTTD 162
              + ++ R RK Q   L  +F   +T + + Q    ER K    R++    ++G    D
Sbjct: 76  LPTTPSEQRQRKIQKDRLVAEFTTSLTNFQKVQRQAAEREKEFVARVRASSRVSGSFPED 135

Query: 163 EELEEMLESGNPAIFTS-GIIDSQISKQALSEIEGRHKDIVRLESSIKELHDMFMDIAML 221
              E  L S          + D +I++  L  I  R   I +LE+ I +++++F D+ M+
Sbjct: 136 SSKERNLVSWESQTQPQVQVQDEEITEDDLRLIHERESSIRQLEADIMDINEIFKDLGMM 195

Query: 222 VENQGEMLDNIELNVMHTVDHVEKARDETKKAVKYQSQARKKLIIIIVLVVVLLGILALI 281
           +  QG+++D+IE NV +   HV++A  +  +A  YQ ++RK L III+++V+ + I++LI
Sbjct: 196 IHEQGDVIDSIEANVENAEVHVQQANQQLSRAADYQRKSRKTLCIIILILVIGVAIISLI 255

Query: 282 I 282
           I
Sbjct: 256 I 256


>gi|34447229 syntaxin 16 isoform b [Homo sapiens]
          Length = 304

 Score = 82.4 bits (202), Expect = 4e-16
 Identities = 63/286 (22%), Positives = 139/286 (48%), Gaps = 19/286 (6%)

Query: 7   QLKAKQLTQDDDTDAVEIAIDNTAFMD-------EFFSEIEETRLNIDKISEHVEEAKKL 59
           QL A+QL  D       I++D  A +        ++   ++E + ++ +I + ++E   L
Sbjct: 22  QLLAEQLADDRMALVSGISLDPEAAIGVTKRPPPKWVDGVDEIQYDVGRIKQKMKELASL 81

Query: 60  YSIILSAPIPEPKTKDD--LEQLTTEIKKRANNVRNKLKSMEKHIEEDEVRSSADLRIRK 117
           +   L+ P  +  ++++  +E  T EI +  +  +  ++++          S  + R+  
Sbjct: 82  HDKHLNRPTLDDSSEEEHAIEITTQEITQLFHRCQRAVQALPSRAR---ACSEQEGRLLG 138

Query: 118 SQHSVLSRKFVEVMTKYNEAQVDFRERSKGRIQRQLEITGKKTTDEELEEMLESGNPAIF 177
           +  + L++   E+ T +  AQ  + +R K R +R          D  +  M +  +  ++
Sbjct: 139 NVVASLAQALQELSTSFRHAQSGYLKRMKNREERSQHFF-----DTSVPLMDDGDDNTLY 193

Query: 178 TSGIIDSQIS--KQALSEIEGRHKDIVRLESSIKELHDMFMDIAMLVENQGEMLDNIELN 235
             G  + Q+   +Q    +E R ++I ++  SI +L+++F D+  ++  QG +LD I+ N
Sbjct: 194 HRGFTEDQLVLVEQNTLMVEEREREIRQIVQSISDLNEIFRDLGAMIVEQGTVLDRIDYN 253

Query: 236 VMHTVDHVEKARDETKKAVKYQSQARKKLIIIIVLVVVLLGILALI 281
           V  +    E    +  KA +YQ + RK L+I+I+ V++++ I+ L+
Sbjct: 254 VEQSCIKTEDGLKQLHKAEQYQKKNRKMLVILILFVIIIVLIVVLV 299


>gi|47778943 syntaxin 16 isoform a [Homo sapiens]
          Length = 325

 Score = 79.7 bits (195), Expect = 3e-15
 Identities = 54/247 (21%), Positives = 124/247 (50%), Gaps = 12/247 (4%)

Query: 39  IEETRLNIDKISEHVEEAKKLYSIILSAPIPEPKTKDD--LEQLTTEIKKRANNVRNKLK 96
           ++E + ++ +I + ++E   L+   L+ P  +  ++++  +E  T EI +  +  +  ++
Sbjct: 82  VDEIQYDVGRIKQKMKELASLHDKHLNRPTLDDSSEEEHAIEITTQEITQLFHRCQRAVQ 141

Query: 97  SMEKHIEEDEVRSSADLRIRKSQHSVLSRKFVEVMTKYNEAQVDFRERSKGRIQRQLEIT 156
           ++          S  + R+  +  + L++   E+ T +  AQ  + +R K R +R     
Sbjct: 142 ALPSRAR---ACSEQEGRLLGNVVASLAQALQELSTSFRHAQSGYLKRMKNREERSQHFF 198

Query: 157 GKKTTDEELEEMLESGNPAIFTSGIIDSQIS--KQALSEIEGRHKDIVRLESSIKELHDM 214
                D  +  M +  +  ++  G  + Q+   +Q    +E R ++I ++  SI +L+++
Sbjct: 199 -----DTSVPLMDDGDDNTLYHRGFTEDQLVLVEQNTLMVEEREREIRQIVQSISDLNEI 253

Query: 215 FMDIAMLVENQGEMLDNIELNVMHTVDHVEKARDETKKAVKYQSQARKKLIIIIVLVVVL 274
           F D+  ++  QG +LD I+ NV  +    E    +  KA +YQ + RK L+I+I+ V+++
Sbjct: 254 FRDLGAMIVEQGTVLDRIDYNVEQSCIKTEDGLKQLHKAEQYQKKNRKMLVILILFVIII 313

Query: 275 LGILALI 281
           + I+ L+
Sbjct: 314 VLIVVLV 320


>gi|198041692 syntaxin 16 isoform d [Homo sapiens]
          Length = 308

 Score = 79.7 bits (195), Expect = 3e-15
 Identities = 54/247 (21%), Positives = 124/247 (50%), Gaps = 12/247 (4%)

Query: 39  IEETRLNIDKISEHVEEAKKLYSIILSAPIPEPKTKDD--LEQLTTEIKKRANNVRNKLK 96
           ++E + ++ +I + ++E   L+   L+ P  +  ++++  +E  T EI +  +  +  ++
Sbjct: 65  VDEIQYDVGRIKQKMKELASLHDKHLNRPTLDDSSEEEHAIEITTQEITQLFHRCQRAVQ 124

Query: 97  SMEKHIEEDEVRSSADLRIRKSQHSVLSRKFVEVMTKYNEAQVDFRERSKGRIQRQLEIT 156
           ++          S  + R+  +  + L++   E+ T +  AQ  + +R K R +R     
Sbjct: 125 ALPSRAR---ACSEQEGRLLGNVVASLAQALQELSTSFRHAQSGYLKRMKNREERSQHFF 181

Query: 157 GKKTTDEELEEMLESGNPAIFTSGIIDSQIS--KQALSEIEGRHKDIVRLESSIKELHDM 214
                D  +  M +  +  ++  G  + Q+   +Q    +E R ++I ++  SI +L+++
Sbjct: 182 -----DTSVPLMDDGDDNTLYHRGFTEDQLVLVEQNTLMVEEREREIRQIVQSISDLNEI 236

Query: 215 FMDIAMLVENQGEMLDNIELNVMHTVDHVEKARDETKKAVKYQSQARKKLIIIIVLVVVL 274
           F D+  ++  QG +LD I+ NV  +    E    +  KA +YQ + RK L+I+I+ V+++
Sbjct: 237 FRDLGAMIVEQGTVLDRIDYNVEQSCIKTEDGLKQLHKAEQYQKKNRKMLVILILFVIII 296

Query: 275 LGILALI 281
           + I+ L+
Sbjct: 297 VLIVVLV 303


>gi|198041688 syntaxin 16 isoform c [Homo sapiens]
          Length = 321

 Score = 79.7 bits (195), Expect = 3e-15
 Identities = 54/247 (21%), Positives = 124/247 (50%), Gaps = 12/247 (4%)

Query: 39  IEETRLNIDKISEHVEEAKKLYSIILSAPIPEPKTKDD--LEQLTTEIKKRANNVRNKLK 96
           ++E + ++ +I + ++E   L+   L+ P  +  ++++  +E  T EI +  +  +  ++
Sbjct: 78  VDEIQYDVGRIKQKMKELASLHDKHLNRPTLDDSSEEEHAIEITTQEITQLFHRCQRAVQ 137

Query: 97  SMEKHIEEDEVRSSADLRIRKSQHSVLSRKFVEVMTKYNEAQVDFRERSKGRIQRQLEIT 156
           ++          S  + R+  +  + L++   E+ T +  AQ  + +R K R +R     
Sbjct: 138 ALPSRAR---ACSEQEGRLLGNVVASLAQALQELSTSFRHAQSGYLKRMKNREERSQHFF 194

Query: 157 GKKTTDEELEEMLESGNPAIFTSGIIDSQIS--KQALSEIEGRHKDIVRLESSIKELHDM 214
                D  +  M +  +  ++  G  + Q+   +Q    +E R ++I ++  SI +L+++
Sbjct: 195 -----DTSVPLMDDGDDNTLYHRGFTEDQLVLVEQNTLMVEEREREIRQIVQSISDLNEI 249

Query: 215 FMDIAMLVENQGEMLDNIELNVMHTVDHVEKARDETKKAVKYQSQARKKLIIIIVLVVVL 274
           F D+  ++  QG +LD I+ NV  +    E    +  KA +YQ + RK L+I+I+ V+++
Sbjct: 250 FRDLGAMIVEQGTVLDRIDYNVEQSCIKTEDGLKQLHKAEQYQKKNRKMLVILILFVIII 309

Query: 275 LGILALI 281
           + I+ L+
Sbjct: 310 VLIVVLV 316


>gi|223972648 t-SNARE domain containing 1 [Homo sapiens]
          Length = 513

 Score = 52.8 bits (125), Expect = 4e-07
 Identities = 55/257 (21%), Positives = 107/257 (41%), Gaps = 17/257 (6%)

Query: 40  EETRLNIDKISEHVEEAKKLYSIILSAPIPEPKTKDDLEQLTTEIKKRANNVRNKLKSME 99
           +E   N+ +I+  V   ++     L  P    + +D L     E  K      + +K M 
Sbjct: 262 QEMSANVFRINSSVTSLERSLQS-LGTPSDTQELRDSLHTAQQETNKTIAASASSVKQMA 320

Query: 100 KHIEEDEVRSSAD---LRIRKSQHSVLSRKFVEVMTKYNEAQVDFRERSKGRIQRQLEIT 156
           + +     RSS     L+  + Q   L  +  + +  Y   Q    E+S+  +    +  
Sbjct: 321 ELL-----RSSCPQERLQQERPQLDRLKTQLSDAIQCYGVVQKKIAEKSRALLP-MAQRG 374

Query: 157 GKKTTDEELEEMLESGNPAIFTSGIIDSQ-------ISKQALSEIEGRHKDIVRLESSIK 209
            K++      E+ +       +  +   Q       I+++ L  I  R + I+++ES++ 
Sbjct: 375 SKQSPQAPFAELADDEKVFNGSDNMWQGQEQALLPDITEEDLEAIRLREEAILQMESNLL 434

Query: 210 ELHDMFMDIAMLVENQGEMLDNIELNVMHTVDHVEKARDETKKAVKYQSQARKKLIIIIV 269
           +++ +  D+A +V  QGE +D+IE ++     H E AR     A ++Q Q  K     + 
Sbjct: 435 DVNQIIKDLASMVSEQGEAVDSIEASLEAASSHAEAARQLLAGASRHQLQRHKIKCCFLS 494

Query: 270 LVVVLLGILALIIGLSV 286
             V  L ++ +II  SV
Sbjct: 495 AGVTALLVIIIIIATSV 511


>gi|94400932 syntaxin 5 [Homo sapiens]
          Length = 355

 Score = 47.8 bits (112), Expect = 1e-05
 Identities = 47/218 (21%), Positives = 94/218 (43%), Gaps = 8/218 (3%)

Query: 74  KDDLEQLTTEIKKRANNVRNKLKSMEKHIEEDEVRSSADLRIRKSQHSVLSRKFVEVMTK 133
           K D+  L  +I +  + VR K     +H++         L+ + +  S   +  +EV T+
Sbjct: 140 KQDINSLNKQIAQLQDFVRAKGSQSGRHLQTHSNTIVVSLQSKLASMSNDFKSVLEVRTE 199

Query: 134 YNEAQVDFRERSKGRIQRQLEITGKKTTDEELEEMLESGNPAIFTSGIIDSQISKQAL-- 191
             + Q   RE+        L +         +    ES         ++DS+ S+Q    
Sbjct: 200 NLKQQRSRREQFSRAPVSALPLAPNHLGGGAVVLGAESHASKDVAIDMMDSRTSQQLQLI 259

Query: 192 ----SEIEGRHKDIVRLESSIKELHDMFMDIAMLVENQGEMLDNIELNVMHTVDHVEKAR 247
               S I+ R   +  +ES+I EL  +F  +A +V+ Q E +  I+ NV+     VE A 
Sbjct: 260 DEQDSYIQSRADTMQNIESTIVELGSIFQQLAHMVKEQEETIQRIDENVLGAQLDVEAAH 319

Query: 248 DETKKAVKYQSQARKKLIIIIVLVVVLLGILALIIGLS 285
            E  K   +QS    + +++ + +++++  +  ++ L+
Sbjct: 320 SEILK--YFQSVTSNRWLMVKIFLILIVFFIIFVVFLA 355


>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
          Length = 1976

 Score = 46.2 bits (108), Expect = 3e-05
 Identities = 62/275 (22%), Positives = 126/275 (45%), Gaps = 28/275 (10%)

Query: 2    KDRLEQLKAKQLTQDDDTDAVEIAIDNTAFMDEFFSEIEETRLNI-------DKISEHVE 54
            K R E  KAK+    + TD  +   +  A +DE   ++ +    +       D  + H  
Sbjct: 1048 KTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEEELQGALARGDDETLHKN 1107

Query: 55   EAKKLYSIILSAPIPEPKTKDDLEQLT-TEIKKRANNVRNKLKSMEKHIEE--DEVRSSA 111
             A K+    L A I E +   + E+ +  + +K+  ++  +L++++  +E+  D   +  
Sbjct: 1108 NALKVVRE-LQAQIAELQEDFESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQ 1166

Query: 112  DLRIRKSQHSVLSRKFVEVMTKYNEAQV-DFRER---SKGRIQRQLEITGK-KTTDEELE 166
            +LR ++ Q     +K +E  TK +EAQ+ D R+R   +   +  QLE   + K   E+ +
Sbjct: 1167 ELRTKREQEVAELKKALEEETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNK 1226

Query: 167  EMLESGNPAIFTSGIIDSQISKQALSEIEGRHKDIVRLESSIKELHDMFMDIAMLVENQG 226
            + LE+ N  +      + ++ +Q  +E E + K   +L++ ++ELH    +   L     
Sbjct: 1227 QGLETDNKEL----ACEVKVLQQVKAESEHKRK---KLDAQVQELHAKVSEGDRLRVELA 1279

Query: 227  EMLDNIELNVMHTVDHVEKARDET-KKAVKYQSQA 260
            E    ++    + +D+V    +E  KK +K+   A
Sbjct: 1280 EKASKLQ----NELDNVSTLLEEAEKKGIKFAKDA 1310



 Score = 41.2 bits (95), Expect = 0.001
 Identities = 60/287 (20%), Positives = 125/287 (43%), Gaps = 32/287 (11%)

Query: 1    MKDRLEQLKAKQLTQDDDTDAVEIAIDNTAFMDEFFSEIEETRLNIDKI-SEHVEEAKKL 59
            +KD   Q++A    +D+    ++      A M ++  E+EE R + D+I ++  E  KKL
Sbjct: 1626 LKDLEAQIEAANKARDE---VIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKL 1682

Query: 60   YSI----------ILSAPIPEPKTKDDLEQLTTEIKKRANNVRNKLKSMEKHIEEDEVRS 109
             S+          + S+       + + ++L  EI   A+  ++ L   ++ +E    + 
Sbjct: 1683 KSLEAEILQLQEELASSERARRHAEQERDELADEITNSASG-KSALLDEKRRLEARIAQL 1741

Query: 110  SADLRIRKSQHSVLSRKFVEVMTKYNEAQVDF-RERSKGR----IQRQLEITGK--KTTD 162
              +L   +S   +L+ +F +   + +    +   ERS  +     ++QLE   K  K   
Sbjct: 1742 EEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQNKELKAKL 1801

Query: 163  EELEEMLESGNPAIFTS-----GIIDSQISKQALSEIEGRHKDIVRLESSIKELHDMFMD 217
            +ELE  ++S   A  ++     G ++ Q+ ++A  E    +K + R E  +KE+     D
Sbjct: 1802 QELEGAVKSKFKATISALEAKIGQLEEQLEQEA-KERAAANKLVRRTEKKLKEIFMQVED 1860

Query: 218  IAMLVENQGEMLDNIELNVMHTVDHVEKARDETKKAVKYQSQARKKL 264
                 +   E ++     +      +E+A +E  +A    + +R+KL
Sbjct: 1861 ERRHADQYKEQMEKANARMKQLKRQLEEAEEEATRA----NASRRKL 1903



 Score = 33.9 bits (76), Expect = 0.17
 Identities = 42/221 (19%), Positives = 92/221 (41%), Gaps = 39/221 (17%)

Query: 73   TKDDLEQLTTEIKKRANNVRNKLKSMEKHIE--EDEVRSSADLRIRKSQHSVLSRKFVEV 130
            +KDD+ +   E++K    +  +++ M   +E  EDE++++ D ++R   +    +   E 
Sbjct: 1519 SKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFER 1578

Query: 131  MTKYNEAQVDFRER-------------SKGRIQRQLEITGKKTTD---EELEEMLESGNP 174
              +  + Q + ++R                R QR L +  KK  +   ++LE  +E+ N 
Sbjct: 1579 DLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIEAANK 1638

Query: 175  AIFTSGIIDSQISKQALSEIEGRHKDIVRLESSIKELHDMFMDIAMLVENQGEMLDNIEL 234
            A         ++ KQ L +++ + KD  R    ++E      +I    +   + L ++E 
Sbjct: 1639 A-------RDEVIKQ-LRKLQAQMKDYQR---ELEEARASRDEIFAQSKESEKKLKSLEA 1687

Query: 235  NVMHTVD----------HVEKARDETKKAVKYQSQARKKLI 265
             ++   +          H E+ RDE    +   +  +  L+
Sbjct: 1688 EILQLQEELASSERARRHAEQERDELADEITNSASGKSALL 1728



 Score = 32.7 bits (73), Expect = 0.38
 Identities = 58/301 (19%), Positives = 127/301 (42%), Gaps = 52/301 (17%)

Query: 2    KDRLEQLKAKQLTQDDDTDAVEIAIDNTAFMDEFFSEIEETRLN--IDKISEHVEEAKKL 59
            K +LE++ A+   +  + + + +   N+ F+ E   ++ E R+     +++E  E+AK L
Sbjct: 968  KLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKE--KKLMEDRIAECSSQLAEEEEKAKNL 1025

Query: 60   YSIILSAPI----------PEPKTKDDLEQLTTEIKKRANNVRNKLKSMEKHIE------ 103
              I     +           E KT+ +LE+   ++     ++++++  ++  I+      
Sbjct: 1026 AKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQL 1085

Query: 104  ---EDEVRSSADLRIRKSQHSVLSRKFV-EVMTKYNEAQVDFRERSKGRIQRQLEITGKK 159
               E+E++ +      ++ H   + K V E+  +  E Q DF      R + + +   K+
Sbjct: 1086 AKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQ---KR 1142

Query: 160  TTDEELEEMLESGNPAIFTSGIIDSQISKQALSEIEGRHKDIVRLESSIKE--------L 211
               EELE +             +D+  ++Q L     R +++  L+ +++E        +
Sbjct: 1143 DLSEELEALKTE------LEDTLDTTAAQQELR--TKREQEVAELKKALEEETKNHEAQI 1194

Query: 212  HDMFMDIAMLVENQGEMLD-------NIELNVMHTVDHVEKARDETK--KAVKYQSQARK 262
             DM    A  +E   E L+       N+E N        ++   E K  + VK +S+ ++
Sbjct: 1195 QDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHKR 1254

Query: 263  K 263
            K
Sbjct: 1255 K 1255



 Score = 32.3 bits (72), Expect = 0.50
 Identities = 30/175 (17%), Positives = 83/175 (47%), Gaps = 22/175 (12%)

Query: 38   EIEETRLNIDKISEHV---EEAKKLYSIILSAPIPEPKTKDDLEQLTTEIKKRANNVRNK 94
            ++EE R  ++++ + +   E+AK    + + A   + + + DL+    + +++   +  +
Sbjct: 1540 QVEEMRTQLEELEDELQATEDAKLRLEVNMQAM--KAQFERDLQTRDEQNEEKKRLLIKQ 1597

Query: 95   LKSMEKHIEEDEVRSSADLRIRKSQHSVLSRKFVEVMTKYNEAQVDFRERSKGRIQRQLE 154
            ++ +E  +E++  + +          +V S+K +E+  K  EAQ++   +++  + +QL 
Sbjct: 1598 VRELEAELEDERKQRAL---------AVASKKKMEIDLKDLEAQIEAANKARDEVIKQLR 1648

Query: 155  ITGKKTTDEELE-EMLESGNPAIFTSGIIDSQISKQALSEIEGRHKDIVRLESSI 208
                +  D + E E   +    IF         SK++  +++    +I++L+  +
Sbjct: 1649 KLQAQMKDYQRELEEARASRDEIFAQ-------SKESEKKLKSLEAEILQLQEEL 1696



 Score = 30.0 bits (66), Expect = 2.5
 Identities = 35/172 (20%), Positives = 69/172 (40%), Gaps = 30/172 (17%)

Query: 1    MKDRLEQLKAK--QLTQDDDTDAVEIAIDNTAFMDEFFSEIEETRLNIDKISEHVEEAKK 58
            ++  LE+++ K  QL ++ +  A ++  +      E F+E EE R  +    + +EE   
Sbjct: 871  VEGELEEMERKHQQLLEEKNILAEQLQAET-----ELFAEAEEMRARLAAKKQELEEILH 925

Query: 59   LYSIILSAPIPEPKTKDDLEQLTTEIKKRANNVRNKLKSMEKHIE------EDEVRSSAD 112
                             DLE    E ++R   ++N+ K M+ HI+      ++E  +   
Sbjct: 926  -----------------DLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQK 968

Query: 113  LRIRKSQHSVLSRKFVEVMTKYNEAQVDFRERSKGRIQRQLEITGKKTTDEE 164
            L++ K       +K  E +    +    F +  K    R  E + +   +EE
Sbjct: 969  LQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEE 1020


>gi|38348356 testis expressed 9 [Homo sapiens]
          Length = 391

 Score = 46.2 bits (108), Expect = 3e-05
 Identities = 42/170 (24%), Positives = 79/170 (46%), Gaps = 11/170 (6%)

Query: 74  KDDLEQLTTEIKKRANNVRNKLKSMEKHIEEDEVRSSADLRIRKSQHSVLSRKFVEVMTK 133
           +++L+ +  E  K+ + ++N LKS  K+ EED +R    + +++SQ       F E   K
Sbjct: 205 QEELDNVVCECNKKEDEIQN-LKSQVKNFEEDFMRQQRTINMQQSQVEKYKTLFEEANKK 263

Query: 134 YNEAQ-----VDFRERSKGRIQRQLEITGKKTTDEELEEMLESGNPAIFTSGIIDSQISK 188
           Y+  Q     V+    +K R+Q+Q   + +  T+  L   LE           +  Q +K
Sbjct: 264 YDGLQQQLSSVERELENKRRLQKQ-AASSQSATEVRLNRALEEAEKYKLELSKL-RQNNK 321

Query: 189 QALSEIEGRHKDIVRLESSIKELHDMFMDIAMLVENQGEMLDNIELNVMH 238
              +E    HK I  L+S  K+L     ++ +  + Q +++D ++   MH
Sbjct: 322 DIANE---EHKKIEVLKSENKKLEKQKGELMIGFKKQLKLIDVLKRQKMH 368


>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
          Length = 2230

 Score = 45.1 bits (105), Expect = 7e-05
 Identities = 48/278 (17%), Positives = 120/278 (43%), Gaps = 19/278 (6%)

Query: 4   RLEQLKAKQLTQDDDTDAVEIAIDNTAFMDEFFSEIEETRLNIDKISEHVE--EAKKLYS 61
           +L++L  K+L + +     ++      F ++    +E+++    KIS+  E  E+  L  
Sbjct: 480 KLQKLHEKELARKEQELTKKLQTREREFQEQMKVALEKSQSEYLKISQEKEQQESLALEE 539

Query: 62  IILSAPIPEPKTKDDLEQLTTEIKKRANNVRNKLKSMEKHIEEDEVRSSADLRIRKSQHS 121
           + L       ++++ L  L  E +     +     S+EK ++E++   S DL +      
Sbjct: 540 LELQKKAILTESENKLRDLQQEAETYRTRILELESSLEKSLQENK-NQSKDLAVHLEAEK 598

Query: 122 VLSRKFVEVMTKYNEAQVDFRERSKGRI----------QRQLEITGKKTTDEELEEMLES 171
               K + VM + ++ +++  +  +  +          Q Q E+   +   E+ +E L  
Sbjct: 599 NKHNKEITVMVEKHKTELESLKHQQDALWTEKLQVLKQQYQTEMEKLREKCEQEKETLLK 658

Query: 172 GNPAIFTSGIIDSQISKQALSEIEGRHKDIVRLESSIKEL----HDMFMDIAMLVENQGE 227
               IF + I   +++++ L +++ +  ++  L S + E+    H +  ++++L +   +
Sbjct: 659 DKEIIFQAHI--EEMNEKTLEKLDVKQTELESLSSELSEVLKARHKLEEELSVLKDQTDK 716

Query: 228 MLDNIELNVMHTVDHVEKARDETKKAVKYQSQARKKLI 265
           M   +E  +    +H ++  D   K  +   Q  +K +
Sbjct: 717 MKQELEAKMDEQKNHHQQQVDSIIKEHEVSIQRTEKAL 754



 Score = 40.0 bits (92), Expect = 0.002
 Identities = 54/219 (24%), Positives = 100/219 (45%), Gaps = 19/219 (8%)

Query: 54  EEAKKLYSIILSAPIPEPKTKDDLEQLTTEIKKRANNVRNKLKSMEKHIEE---DEVRSS 110
           EE +K  S          K K ++++    I+K +   R  L+     +++   D ++ S
Sbjct: 414 EELEKALSTAQKTEEARRKLKAEMDEQIKTIEKTSEEERISLQQELSRVKQEVVDVMKKS 473

Query: 111 ADLRIRKSQ---HSVLSRKFVEVMTKYNEAQVDFRERSKGRIQRQ----LEITGKKTTDE 163
           ++ +I K Q      L+RK  E+  K    + +F+E+ K  +++     L+I+ +K   E
Sbjct: 474 SEEQIAKLQKLHEKELARKEQELTKKLQTREREFQEQMKVALEKSQSEYLKISQEKEQQE 533

Query: 164 ELE-EMLESGNPAIFTSGIIDSQISKQALSEIEGRHKDI-VRLESSIKELHDMFMDIAML 221
            L  E LE    AI T      +  +Q       R  ++   LE S++E  +   D+A+ 
Sbjct: 534 SLALEELELQKKAILTESENKLRDLQQEAETYRTRILELESSLEKSLQENKNQSKDLAVH 593

Query: 222 VENQGEMLDNIELNVMHTVDHVEKARDETKKAVKYQSQA 260
           +E + +   N E+ VM     VEK + E  +++K+Q  A
Sbjct: 594 LEAE-KNKHNKEITVM-----VEKHKTEL-ESLKHQQDA 625



 Score = 32.7 bits (73), Expect = 0.38
 Identities = 35/182 (19%), Positives = 77/182 (42%), Gaps = 22/182 (12%)

Query: 41   ETRLNIDKISEHVEEAKKLYSIILSAPIPEPKTKDDLEQLTTEIKKRANNVRNKLKSMEK 100
            E +  I  + E +EE  K YS+I++  + +   K++++           N+ N    ++K
Sbjct: 1789 EDQSMIGHLQEELEEKNKKYSLIVAQHVEKEGGKNNIQ--------AKQNLENVFDDVQK 1840

Query: 101  HIEEDEVRSSADLRIRKSQHSVLSRKFVEVMTKYNEAQVDFRERSKGRIQRQLEITGKKT 160
             ++E E+      +  K   S L R+      + +  +++       ++Q   ++ G+  
Sbjct: 1841 TLQEKELTCQILEQKIKELDSCLVRQ-----KEVHRVEMEELTSKYEKLQALQQMDGRNK 1895

Query: 161  TDEELEEMLESGNPAIFTSGIIDSQISKQALSEIEGRHKDI-VRLESSIKELHDMFMDIA 219
              E LEE  E  + +          +  + LS +E +H D+  +L  + +E   +  +I 
Sbjct: 1896 PTELLEENTEEKSKS--------HLVQPKLLSNMEAQHNDLEFKLAGAEREKQKLGKEIV 1947

Query: 220  ML 221
             L
Sbjct: 1948 RL 1949


>gi|64085252 hypothetical protein LOC145508 [Homo sapiens]
          Length = 1094

 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 59/245 (24%), Positives = 113/245 (46%), Gaps = 35/245 (14%)

Query: 43  RLNIDKISEHVEEAKKLYSIILSAPIPEPKTKD------DLEQLTTEIK---KRANNVRN 93
           +LN   ++  +EE K+           E K K+       +E LT E++   K+   + +
Sbjct: 371 QLNFSAMASELEEVKRCM---------ERKDKEKAHLASQVENLTRELENGEKQQLQMLD 421

Query: 94  KLKSMEKHIEEDEV-RSSADLRIRK-SQHSVLSRKFVE-VMTKYNEAQVDFRERSKGR-- 148
           +LK ++ H +  E  R  ADL+I + ++H+  + K  E  +++  +++    E  K R  
Sbjct: 422 RLKEIQNHFDTCEAERKHADLQISELTRHAEDATKQAERYLSELQQSEALKEEAEKRRED 481

Query: 149 --IQRQLEITGKKTTDEELEEMLESGNPAIFTSGIIDSQISKQALSEIEGRHKDIVRLES 206
             ++ Q  I   K   ++LE  LE  +  +      ++QI K+        +  + ++E+
Sbjct: 482 LKLKAQESIRQWKLKHKKLERALEKQSETVDELTGKNNQILKEKDELKTQLYAALQQIEN 541

Query: 207 SIKELHDMFMDIAMLVE---NQGEMLDNI-------ELNVMHTVDHVEKARDETKKAVKY 256
             KEL+D+    A+  E   ++ E L +I       EL V +++D + +   E KK  K 
Sbjct: 542 LRKELNDVLTKRALQEEELHSKEEKLRDIKSHQADLELEVKNSLDTIHRLESELKKQSKI 601

Query: 257 QSQAR 261
           QSQ +
Sbjct: 602 QSQMK 606


>gi|4507285 syntaxin 10 [Homo sapiens]
          Length = 249

 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 50/219 (22%), Positives = 100/219 (45%), Gaps = 17/219 (7%)

Query: 74  KDDLEQLTTEIKKRANNVRNKLKSMEKHIEEDEVRS------SADLRIRKSQHSVLSRKF 127
           +++L+  T E++    ++   L+ +E+ I   E         + DL+ RK     + R+ 
Sbjct: 40  REELDWTTNELRNGLRSIEWDLEDLEETIGIVEANPGKFKLPAGDLQERKVFVERM-REA 98

Query: 128 VEVMTKY--NEAQVDFRERSKGRIQRQLEITGKKTTDEELEEMLESGNPAIFTSGIIDSQ 185
           V+ M  +  +   V F ER+   I     + GK    +   ++L++   +  +  I + Q
Sbjct: 99  VQEMKDHMVSPTAVAFLERNNREI-----LAGKPAAQKSPSDLLDASAVSATSRYIEEQQ 153

Query: 186 ISKQALSEIEGRHKDIVRLESSIKELHDMFMDIAMLVENQGEMLDNIELNVMHTVDHVEK 245
            ++Q + + + +  ++V    SI+ L  M   +   ++ QG MLD     + HT   ++ 
Sbjct: 154 ATQQLIMDEQDQQLEMV--SGSIQVLKHMSGRVGEELDEQGIMLDAFAQEMDHTQSRMDG 211

Query: 246 ARDETKKAVKYQSQARKKLIIIIVLVVVLLGILALIIGL 284
              +  K V + +  R++   I VLV VLL +L L+  L
Sbjct: 212 VLRKLAK-VSHMTSDRRQWCAIAVLVGVLLLVLILLFSL 249


>gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens]
          Length = 1946

 Score = 42.4 bits (98), Expect = 5e-04
 Identities = 52/253 (20%), Positives = 113/253 (44%), Gaps = 35/253 (13%)

Query: 6    EQLKAKQ--LTQDDDTDAVEIAIDNT--AFMDEFFSEIEETRLNID----KISEHVEEAK 57
            E+LKAKQ  LTQ+ +   +++  +    A ++E    + ++++ ++    ++SE VEE +
Sbjct: 883  EELKAKQVSLTQEKNDLILQLQAEQETLANVEEQCEWLIKSKIQLEARVKELSERVEEEE 942

Query: 58   KLYSIILSAP-------IPEPKTKDDLEQLTTEIKKRANNVRNKLKSMEKHIE------- 103
            ++ S + +             K  DDLE +  + +K      +K+K++ + +E       
Sbjct: 943  EINSELTARGRKLEDECFELKKEIDDLETMLVKSEKEKRTTEHKVKNLTEEVEFLNEDIS 1002

Query: 104  ----------EDEVRSSADLRIRKSQHSVLSRKFVEVMTKYNEAQVDFRERSKGRI--QR 151
                      E   ++  DL + + + S LS+  +++  + +E +    +  K R+  +R
Sbjct: 1003 KLNRAAKVVQEAHQQTLDDLHMEEEKLSSLSKANLKLEQQVDELEGALEQERKARMNCER 1062

Query: 152  QL-EITGKKTTDEELEEMLESGNPAIFTSGIIDSQISKQALSEIEGRHKDIVRLESSIKE 210
            +L ++ G    + E  E LES    +            Q  S++E     + +L+ ++KE
Sbjct: 1063 ELHKLEGNLKLNRESMENLESSQRHLAEELRKKELELSQMNSKVENEKGLVAQLQKTVKE 1122

Query: 211  LHDMFMDIAMLVE 223
            L     D+   +E
Sbjct: 1123 LQTQIKDLKEKLE 1135


>gi|110815815 centlein isoform 1 [Homo sapiens]
          Length = 1406

 Score = 42.4 bits (98), Expect = 5e-04
 Identities = 39/174 (22%), Positives = 84/174 (48%), Gaps = 14/174 (8%)

Query: 6   EQLKAKQLTQDDDTDAVEIAIDN-TAFMDEFFSEIEETRLNIDKISEHVEEAKKLYSIIL 64
           EQ ++    + +D    +IA+D   AF+ + FS++E+      K  +  +E K     + 
Sbjct: 177 EQRESVLKQEINDLVKRKIAVDEENAFLRKEFSDLEK------KFKDKSQEIKDTKECVQ 230

Query: 65  SAPIPEPKTKDDLEQLTTEIKKRANNVRN---KLKSMEKHIEEDEVRSSADLRIRKSQHS 121
           +          +LE+   ++  R  ++ N   KL+  E H+ +++   S D +I+  + +
Sbjct: 231 NKEEQNRLVIKNLEEENKKLSTRCTDLLNDLEKLRKQEAHLRKEKY--STDAKIKTFEDN 288

Query: 122 VL-SRKFVEV-MTKYNEAQVDFRERSKGRIQRQLEITGKKTTDEELEEMLESGN 173
           ++ +RK VEV  +KYN   +    +    IQ+ ++IT  +   +EL+ + +  +
Sbjct: 289 LIEARKEVEVSQSKYNALSLQLSNKQTELIQKDMDITLVRKELQELQNLYKQNS 342


>gi|167555106 centlein isoform 2 [Homo sapiens]
          Length = 391

 Score = 42.4 bits (98), Expect = 5e-04
 Identities = 39/174 (22%), Positives = 84/174 (48%), Gaps = 14/174 (8%)

Query: 6   EQLKAKQLTQDDDTDAVEIAIDN-TAFMDEFFSEIEETRLNIDKISEHVEEAKKLYSIIL 64
           EQ ++    + +D    +IA+D   AF+ + FS++E+      K  +  +E K     + 
Sbjct: 177 EQRESVLKQEINDLVKRKIAVDEENAFLRKEFSDLEK------KFKDKSQEIKDTKECVQ 230

Query: 65  SAPIPEPKTKDDLEQLTTEIKKRANNVRN---KLKSMEKHIEEDEVRSSADLRIRKSQHS 121
           +          +LE+   ++  R  ++ N   KL+  E H+ +++   S D +I+  + +
Sbjct: 231 NKEEQNRLVIKNLEEENKKLSTRCTDLLNDLEKLRKQEAHLRKEKY--STDAKIKTFEDN 288

Query: 122 VL-SRKFVEV-MTKYNEAQVDFRERSKGRIQRQLEITGKKTTDEELEEMLESGN 173
           ++ +RK VEV  +KYN   +    +    IQ+ ++IT  +   +EL+ + +  +
Sbjct: 289 LIEARKEVEVSQSKYNALSLQLSNKQTELIQKDMDITLVRKELQELQNLYKQNS 342


>gi|4502443 dystonin isoform 1e precursor [Homo sapiens]
          Length = 2649

 Score = 42.0 bits (97), Expect = 6e-04
 Identities = 41/193 (21%), Positives = 88/193 (45%), Gaps = 15/193 (7%)

Query: 76   DLEQLTTEIKKRANNVRNKLKSMEKHIEEDEVRSSADLRIRKSQHSV----LSRKFVEVM 131
            +LE++  E+KK+ + V  +L          +VR +A+  +RK Q +V    L +   E  
Sbjct: 1142 ELERMVAELKKQKSRVEEEL---------PKVREAAENELRKQQRNVEDISLQKIRAESE 1192

Query: 132  TKYNEAQVDFRERSKGRIQRQLEITGKKTTDEELEEMLESGNPAIFTSGIIDSQISKQAL 191
             K    +++   R K   +R+LE   + T + E +      N   F + + ++  +++ L
Sbjct: 1193 AKQYRRELETIVREKEAAERELERVRQLTIEAEAKRAAVEENLLNFRNQLEENTFTRRTL 1252

Query: 192  SEIEGRHKDIVRLESSIKELHDMFMDIAMLVENQGEMLDNIELNVMHTVDHVEKARDETK 251
             E   + KD+  L    ++ + +  ++    +N+ E+L  I+          + A  + K
Sbjct: 1253 -EDHLKRKDL-SLNDLEQQKNKLMEELRRKRDNEEELLKLIKQMEKDLAFQKQVAEKQLK 1310

Query: 252  KAVKYQSQARKKL 264
            +  K + +AR+K+
Sbjct: 1311 EKQKIELEARRKI 1323


>gi|114155142 nuclear pore complex-associated protein TPR [Homo
            sapiens]
          Length = 2363

 Score = 41.6 bits (96), Expect = 8e-04
 Identities = 34/157 (21%), Positives = 75/157 (47%), Gaps = 29/157 (18%)

Query: 70   EPKTKDDLEQLTTEIKK---RANNVRNKLKSMEKHIEE-------------------DEV 107
            +P  K+D++ L +++++   + N+++ +LK+   ++E+                   +EV
Sbjct: 927  QPSNKEDVDDLVSQLRQTEEQVNDLKERLKTSTSNVEQYQAMVTSLEESLNKEKQVTEEV 986

Query: 108  RSSADLRIRKSQ--HSVLSRKFVEVMTKYNEAQVDFRERSKGRIQRQLEITGKKT---TD 162
            R + ++R+++S    + L +K +EV  +  E Q D R   +   Q+  E+  KKT     
Sbjct: 987  RKNIEVRLKESAEFQTQLEKKLMEVEKEKQELQDDKRRAIESMEQQLSEL--KKTLSSVQ 1044

Query: 163  EELEEMLESGNPAIFTSGIIDSQISKQALSEIEGRHK 199
             E++E L+  + A+           +QA   +E ++K
Sbjct: 1045 NEVQEALQRASTALSNEQQARRDCQEQAKIAVEAQNK 1081



 Score = 28.9 bits (63), Expect = 5.5
 Identities = 21/107 (19%), Positives = 50/107 (46%), Gaps = 7/107 (6%)

Query: 83   EIKKRANNVRNKLKSMEKHIEEDEVRSSADLRIRKSQHSVLSRKFVEVMTKYNEAQVDFR 142
            E+K+  N    K KS+E  +E         L  ++++   L  + V++ ++ +  + D +
Sbjct: 1478 ELKETLNQAETKSKSLESQVE----NLQKTLSEKETEARNLQEQTVQLQSELSRLRQDLQ 1533

Query: 143  ERSKGRIQRQLEITGKKTTDEELEEMLESGNPAIFTSGIIDSQISKQ 189
            +R+    Q + +IT K   +E+  + + +    I     +  Q++K+
Sbjct: 1534 DRTTQEEQLRQQITEK---EEKTRKAIVAAKSKIAHLAGVKDQLTKE 1577


>gi|31982906 cingulin-like 1 [Homo sapiens]
          Length = 1302

 Score = 41.6 bits (96), Expect = 8e-04
 Identities = 52/235 (22%), Positives = 99/235 (42%), Gaps = 27/235 (11%)

Query: 1    MKDRLEQLKAKQLTQDDDTDAVEIAIDNTAFMDEFFSEIEETRLNIDKISEHVEEAKKLY 60
            +KD   +L+AK   +DD +  V+   D  + ++    E+EE R N D +SE +  +++  
Sbjct: 1042 LKDLEYELEAKSHLKDDRSRLVKQMEDKVSQLE---MELEEERNNSDLLSERISRSREQM 1098

Query: 61   SIILSAPIPEPKTKDD-------LEQLTTEIKKRANNVRNKLKS--------MEKHIEED 105
              + +  + E   + D       LE+   ++K R  ++    +S        ME  I E 
Sbjct: 1099 EQLRNELLQERAARQDLECDKISLERQNKDLKSRIIHLEGSYRSSKEGLVVQMEARIAEL 1158

Query: 106  EVRSSADLRIRKS---QHSVLSRKFVEVMTKYNEAQVDFRERSKGRIQRQLEITGKKTTD 162
            E R  ++ R R +    +  L RK  E++ + ++  +   ++   + Q  L +   K   
Sbjct: 1159 EDRLESEERDRANLQLSNRRLERKVKELVMQVDDEHLSLTDQ---KDQLSLRLKAMKRQV 1215

Query: 163  EELEE---MLESGNPAIFTSGIIDSQISKQALSEIEGRHKDIVRLESSIKELHDM 214
            EE EE    LES    +         +++    ++    KD+   +   K L DM
Sbjct: 1216 EEAEEEIDRLESSKKKLQRELEEQMDMNEHLQGQLNSMKKDLRLKKLPSKVLDDM 1270


>gi|90652855 EF-hand calcium binding domain 5 isoform a [Homo
           sapiens]
          Length = 1503

 Score = 40.8 bits (94), Expect = 0.001
 Identities = 37/151 (24%), Positives = 69/151 (45%), Gaps = 4/151 (2%)

Query: 28  NTAFMDEFFSEIEETRLNIDKISEHVEEAKKLYSIILSAP-IP-EPKTKDDLEQLTTEIK 85
           N +   E     +E R    +   ++ E K+L+  + S P +P +  T   +E+   EIK
Sbjct: 2   NESASQEELRPAQENRKEDKERKWNLTEVKELHETLQSVPDVPVKEDTNSVVEKAMDEIK 61

Query: 86  KRANNVRNKLKSMEKHIEEDEVRSSADLRIRKSQHSVLSRKFVEVMTKYNEA-QVDFRER 144
            +  N+  + K     I++ +  +S ++ IRKS   + +    E+ +K     + +  ER
Sbjct: 62  SQELNLEGQRKISPGSIKDSKTEASGNIAIRKSAKVIFALDETELKSKPEHTWKKNLFER 121

Query: 145 SKGRIQ-RQLEITGKKTTDEELEEMLESGNP 174
            + R Q  Q +I  K+   +ELE+  E   P
Sbjct: 122 MEARAQAMQQKIIDKENLKKELEKKAEKKLP 152


>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
            sapiens]
          Length = 1972

 Score = 40.4 bits (93), Expect = 0.002
 Identities = 59/278 (21%), Positives = 121/278 (43%), Gaps = 35/278 (12%)

Query: 2    KDRLEQLKAKQLTQDDDTDAVEIAIDNTAFMDEFFSEI----EETRLNIDKISEHVEEAK 57
            K R E  K K+  + D +D  E   D  A + E   ++    EE +  + ++ + + +  
Sbjct: 1048 KSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKN 1107

Query: 58   KLYSIILSAPIPEPKTKDDLEQ---LTTEIKKRANNVRNKLKSMEKHIEE--DEVRSSAD 112
                 I          ++DL+       + +K+  ++  +L++++  +E+  D   +  +
Sbjct: 1108 NALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQE 1167

Query: 113  LRIRKSQHSVLSRKFVEVMTKYNEAQV-DFRERSKGRIQ---RQLE-ITGKKTTDEELEE 167
            LR ++ Q   + +K ++  T+ +EAQV + R++    ++    QLE     K   ++ ++
Sbjct: 1168 LRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQ 1227

Query: 168  MLESGNPAIFTSGIIDSQISKQALSEIEGRHKDIVRLESSIKELHDMFMDIAMLVENQGE 227
             LE  N  +      + ++  QA  E+E + K   +LE+ ++EL     D        GE
Sbjct: 1228 TLEKENADLAG----ELRVLGQAKQEVEHKKK---KLEAQVQELQSKCSD--------GE 1272

Query: 228  MLDNIELNVMHTVDHVEKARDETKKAVKYQSQARKKLI 265
                 ELN     D V K ++E +      ++A  K I
Sbjct: 1273 RA-RAELN-----DKVHKLQNEVESVTGMLNEAEGKAI 1304



 Score = 34.7 bits (78), Expect = 0.10
 Identities = 55/271 (20%), Positives = 116/271 (42%), Gaps = 35/271 (12%)

Query: 1    MKDRL-EQLKAKQ-LTQDDDTDAVEIAIDNTAFMDEFFSEIEETRLNIDKISEHVEEAKK 58
            ++D+L E+++AKQ L +   T  ++++ D+   + +F S +E       +  + +E   +
Sbjct: 1348 LQDQLDEEMEAKQNLERHISTLNIQLS-DSKKKLQDFASTVEALEEGKKRFQKEIENLTQ 1406

Query: 59   LYSIILSAPIPEPKTKDDLEQLTTEIKKRANNVRNKLKSMEKHIEEDEVRSSADLRIRKS 118
             Y    +A     KTK+ L+Q   ++    +N R  + ++EK             + RK 
Sbjct: 1407 QYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEK-------------KQRKF 1453

Query: 119  QHSVLSRKFVEVMTKYNEAQVDFRERSKGRIQRQLEITGKKTTDEELEEMLESGNPAIFT 178
               +   K   + +KY +      ER +   + + + T   +    LEE LE+      T
Sbjct: 1454 DQLLAEEK--NISSKYAD------ERDRAEAEAREKETKALSLARALEEALEAKEELERT 1505

Query: 179  SGIIDSQISKQALSEIEGRHKDIVRLESSIKELHDMFMDIAMLVENQGEMLD-------N 231
            + ++ +++ +  +S  +   K++  LE S + L     ++   +E   + L         
Sbjct: 1506 NKMLKAEM-EDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLR 1564

Query: 232  IELNVMHTVDHVEK---ARDETKKAVKYQSQ 259
            +E+N+       E+   ARDE  +  + Q Q
Sbjct: 1565 LEVNMQALKGQFERDLQARDEQNEEKRRQLQ 1595



 Score = 32.3 bits (72), Expect = 0.50
 Identities = 39/185 (21%), Positives = 85/185 (45%), Gaps = 16/185 (8%)

Query: 38   EIEETRLNIDKISEHVEEAKKLYSIILSAPIPEPKTKDDLEQLTTEIKKRANNVRNKLKS 97
            E+++T+    K    ++E ++ +S +      E     +  Q  TE+   A  +R +L +
Sbjct: 860  ELQKTKERQQKAENELKELEQKHSQLTE----EKNLLQEQLQAETELYAEAEEMRVRLAA 915

Query: 98   MEKHIEE--DEVRSSADLRIRKSQHSVLSRKFVEVMTKYNEAQVDFRERSKGRIQRQLEI 155
             ++ +EE   E+ +  +    + Q     RK +       E Q++  E ++ ++Q + ++
Sbjct: 916  KKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLE-KV 974

Query: 156  TGK---KTTDEELEEMLESGNPAIFTSGIIDSQISKQA--LSEIEGRHKDIVRL----ES 206
            T +   K  ++E+  M +  N       +++ +IS     L+E E + K++ +L    ES
Sbjct: 975  TAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHES 1034

Query: 207  SIKEL 211
             I EL
Sbjct: 1035 MISEL 1039


>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
            sapiens]
          Length = 1979

 Score = 40.4 bits (93), Expect = 0.002
 Identities = 59/278 (21%), Positives = 121/278 (43%), Gaps = 35/278 (12%)

Query: 2    KDRLEQLKAKQLTQDDDTDAVEIAIDNTAFMDEFFSEI----EETRLNIDKISEHVEEAK 57
            K R E  K K+  + D +D  E   D  A + E   ++    EE +  + ++ + + +  
Sbjct: 1055 KSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKN 1114

Query: 58   KLYSIILSAPIPEPKTKDDLEQ---LTTEIKKRANNVRNKLKSMEKHIEE--DEVRSSAD 112
                 I          ++DL+       + +K+  ++  +L++++  +E+  D   +  +
Sbjct: 1115 NALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQE 1174

Query: 113  LRIRKSQHSVLSRKFVEVMTKYNEAQV-DFRERSKGRIQ---RQLE-ITGKKTTDEELEE 167
            LR ++ Q   + +K ++  T+ +EAQV + R++    ++    QLE     K   ++ ++
Sbjct: 1175 LRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQ 1234

Query: 168  MLESGNPAIFTSGIIDSQISKQALSEIEGRHKDIVRLESSIKELHDMFMDIAMLVENQGE 227
             LE  N  +      + ++  QA  E+E + K   +LE+ ++EL     D        GE
Sbjct: 1235 TLEKENADLAG----ELRVLGQAKQEVEHKKK---KLEAQVQELQSKCSD--------GE 1279

Query: 228  MLDNIELNVMHTVDHVEKARDETKKAVKYQSQARKKLI 265
                 ELN     D V K ++E +      ++A  K I
Sbjct: 1280 RA-RAELN-----DKVHKLQNEVESVTGMLNEAEGKAI 1311



 Score = 34.7 bits (78), Expect = 0.10
 Identities = 55/271 (20%), Positives = 116/271 (42%), Gaps = 35/271 (12%)

Query: 1    MKDRL-EQLKAKQ-LTQDDDTDAVEIAIDNTAFMDEFFSEIEETRLNIDKISEHVEEAKK 58
            ++D+L E+++AKQ L +   T  ++++ D+   + +F S +E       +  + +E   +
Sbjct: 1355 LQDQLDEEMEAKQNLERHISTLNIQLS-DSKKKLQDFASTVEALEEGKKRFQKEIENLTQ 1413

Query: 59   LYSIILSAPIPEPKTKDDLEQLTTEIKKRANNVRNKLKSMEKHIEEDEVRSSADLRIRKS 118
             Y    +A     KTK+ L+Q   ++    +N R  + ++EK             + RK 
Sbjct: 1414 QYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEK-------------KQRKF 1460

Query: 119  QHSVLSRKFVEVMTKYNEAQVDFRERSKGRIQRQLEITGKKTTDEELEEMLESGNPAIFT 178
               +   K   + +KY +      ER +   + + + T   +    LEE LE+      T
Sbjct: 1461 DQLLAEEK--NISSKYAD------ERDRAEAEAREKETKALSLARALEEALEAKEELERT 1512

Query: 179  SGIIDSQISKQALSEIEGRHKDIVRLESSIKELHDMFMDIAMLVENQGEMLD-------N 231
            + ++ +++ +  +S  +   K++  LE S + L     ++   +E   + L         
Sbjct: 1513 NKMLKAEM-EDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLR 1571

Query: 232  IELNVMHTVDHVEK---ARDETKKAVKYQSQ 259
            +E+N+       E+   ARDE  +  + Q Q
Sbjct: 1572 LEVNMQALKGQFERDLQARDEQNEEKRRQLQ 1602



 Score = 32.3 bits (72), Expect = 0.50
 Identities = 39/185 (21%), Positives = 85/185 (45%), Gaps = 16/185 (8%)

Query: 38   EIEETRLNIDKISEHVEEAKKLYSIILSAPIPEPKTKDDLEQLTTEIKKRANNVRNKLKS 97
            E+++T+    K    ++E ++ +S +      E     +  Q  TE+   A  +R +L +
Sbjct: 867  ELQKTKERQQKAENELKELEQKHSQLTE----EKNLLQEQLQAETELYAEAEEMRVRLAA 922

Query: 98   MEKHIEE--DEVRSSADLRIRKSQHSVLSRKFVEVMTKYNEAQVDFRERSKGRIQRQLEI 155
             ++ +EE   E+ +  +    + Q     RK +       E Q++  E ++ ++Q + ++
Sbjct: 923  KKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKLQLE-KV 981

Query: 156  TGK---KTTDEELEEMLESGNPAIFTSGIIDSQISKQA--LSEIEGRHKDIVRL----ES 206
            T +   K  ++E+  M +  N       +++ +IS     L+E E + K++ +L    ES
Sbjct: 982  TAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHES 1041

Query: 207  SIKEL 211
             I EL
Sbjct: 1042 MISEL 1046


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.131    0.338 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,668,505
Number of Sequences: 37866
Number of extensions: 348362
Number of successful extensions: 2131
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 52
Number of HSP's successfully gapped in prelim test: 267
Number of HSP's that attempted gapping in prelim test: 1864
Number of HSP's gapped (non-prelim): 507
length of query: 289
length of database: 18,247,518
effective HSP length: 101
effective length of query: 188
effective length of database: 14,423,052
effective search space: 2711533776
effective search space used: 2711533776
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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