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Search of human proteins with 4759128
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4759128 solute carrier family 24 (sodium/potassium/calcium
exchanger), member 1 [Homo sapiens]
(1099 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4759128 solute carrier family 24 (sodium/potassium/calcium ex... 2183 0.0
gi|9966787 solute carrier family 24 (sodium/potassium/calcium ex... 346 6e-95
gi|29788985 solute carrier family 24 member 4 isoform 2 precurso... 222 1e-57
gi|29788987 solute carrier family 24 member 4 isoform 3 [Homo sa... 215 2e-55
gi|24111228 solute carrier family 24 member 4 isoform 1 precurso... 215 2e-55
gi|31563526 solute carrier family 24 (sodium/potassium/calcium e... 209 9e-54
gi|45504369 solute carrier family 24, member 5 [Homo sapiens] 169 1e-41
gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Hom... 126 1e-28
gi|13540523 nucleosomal binding protein 1 [Homo sapiens] 93 1e-18
gi|17975763 myelin transcription factor 1 [Homo sapiens] 89 3e-17
gi|21735415 centromere protein B [Homo sapiens] 84 6e-16
gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens] 81 5e-15
gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi... 80 1e-14
gi|55956788 nucleolin [Homo sapiens] 79 2e-14
gi|39995086 solute carrier family 24 member 6 [Homo sapiens] 78 4e-14
gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens] 74 6e-13
gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens] 74 6e-13
gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1 ... 73 2e-12
gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2 ... 73 2e-12
gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens] 72 3e-12
gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens] 72 3e-12
gi|60498973 myelin transcription factor 1-like [Homo sapiens] 71 5e-12
gi|156142199 euchromatic histone-lysine N-methyltransferase 2 is... 70 1e-11
gi|156142197 euchromatic histone-lysine N-methyltransferase 2 is... 70 1e-11
gi|61676188 HECT, UBA and WWE domain containing 1 [Homo sapiens] 70 1e-11
gi|116284392 mucin 2 precursor [Homo sapiens] 69 3e-11
gi|4504487 histidine rich calcium binding protein precursor [Hom... 69 3e-11
gi|100816397 MYST histone acetyltransferase (monocytic leukemia)... 67 9e-11
gi|24415404 MDN1, midasin homolog [Homo sapiens] 67 9e-11
gi|22749303 hypothetical protein LOC196477 [Homo sapiens] 67 9e-11
>gi|4759128 solute carrier family 24 (sodium/potassium/calcium
exchanger), member 1 [Homo sapiens]
Length = 1099
Score = 2183 bits (5656), Expect = 0.0
Identities = 1099/1099 (100%), Positives = 1099/1099 (100%)
Query: 1 MGKLIRMGPQERWLLRTKRLHWSRLLFLLGMLIIGSTYQHLRRPRGLSSLWAAVSSHQPI 60
MGKLIRMGPQERWLLRTKRLHWSRLLFLLGMLIIGSTYQHLRRPRGLSSLWAAVSSHQPI
Sbjct: 1 MGKLIRMGPQERWLLRTKRLHWSRLLFLLGMLIIGSTYQHLRRPRGLSSLWAAVSSHQPI 60
Query: 61 KLASRDLSSEEMMMMSSSPSKPSSEMGGKMLVPQASVGSDEATLSMTVENIPSMPKRTAK 120
KLASRDLSSEEMMMMSSSPSKPSSEMGGKMLVPQASVGSDEATLSMTVENIPSMPKRTAK
Sbjct: 61 KLASRDLSSEEMMMMSSSPSKPSSEMGGKMLVPQASVGSDEATLSMTVENIPSMPKRTAK 120
Query: 121 MIPTTTKNNYSPTAAGTERRKEDTPTSSRTLTYYTSTSSRQIVKKYTPTPRGEMKSYSPT 180
MIPTTTKNNYSPTAAGTERRKEDTPTSSRTLTYYTSTSSRQIVKKYTPTPRGEMKSYSPT
Sbjct: 121 MIPTTTKNNYSPTAAGTERRKEDTPTSSRTLTYYTSTSSRQIVKKYTPTPRGEMKSYSPT 180
Query: 181 QVREKVKYTPSPRGRRVGTYVPSTFMTMETSHAITPRTTVKDSDITATYKILETNSLKRI 240
QVREKVKYTPSPRGRRVGTYVPSTFMTMETSHAITPRTTVKDSDITATYKILETNSLKRI
Sbjct: 181 QVREKVKYTPSPRGRRVGTYVPSTFMTMETSHAITPRTTVKDSDITATYKILETNSLKRI 240
Query: 241 MEETTPTTLKGMFDSTPTFLTHEVEANVLTSPRSVMEKNNLFPPRRVESNSSAHPWGLVG 300
MEETTPTTLKGMFDSTPTFLTHEVEANVLTSPRSVMEKNNLFPPRRVESNSSAHPWGLVG
Sbjct: 241 MEETTPTTLKGMFDSTPTFLTHEVEANVLTSPRSVMEKNNLFPPRRVESNSSAHPWGLVG 300
Query: 301 KSNPKTPQGTVLLHTPATSEGQVTISTMTGSSPAETKAFTAAWSLRNPSPRTSVSAIKTA 360
KSNPKTPQGTVLLHTPATSEGQVTISTMTGSSPAETKAFTAAWSLRNPSPRTSVSAIKTA
Sbjct: 301 KSNPKTPQGTVLLHTPATSEGQVTISTMTGSSPAETKAFTAAWSLRNPSPRTSVSAIKTA 360
Query: 361 PAIVWRLAKKPSTAPSTSTTPTVRAKLTMQVHHCVVVKPTPAMLTTPSPSLTTALLPEEL 420
PAIVWRLAKKPSTAPSTSTTPTVRAKLTMQVHHCVVVKPTPAMLTTPSPSLTTALLPEEL
Sbjct: 361 PAIVWRLAKKPSTAPSTSTTPTVRAKLTMQVHHCVVVKPTPAMLTTPSPSLTTALLPEEL 420
Query: 421 SPSPSVLPPSLPDLHPKGEYPPDLFSVEERRQGWVVLHVFGMMYVFVALAIVCDEYFVPA 480
SPSPSVLPPSLPDLHPKGEYPPDLFSVEERRQGWVVLHVFGMMYVFVALAIVCDEYFVPA
Sbjct: 421 SPSPSVLPPSLPDLHPKGEYPPDLFSVEERRQGWVVLHVFGMMYVFVALAIVCDEYFVPA 480
Query: 481 LGVITDKLQISEDVAGATFMAAGGSAPELFTSLIGVFISHSNVGIGTIVGSAVFNILFVI 540
LGVITDKLQISEDVAGATFMAAGGSAPELFTSLIGVFISHSNVGIGTIVGSAVFNILFVI
Sbjct: 481 LGVITDKLQISEDVAGATFMAAGGSAPELFTSLIGVFISHSNVGIGTIVGSAVFNILFVI 540
Query: 541 GTCSLFSREILNLTWWPLFRDVSFYILDLIMLILFFLDSLIAWWESLLLLLAYAFYVFTM 600
GTCSLFSREILNLTWWPLFRDVSFYILDLIMLILFFLDSLIAWWESLLLLLAYAFYVFTM
Sbjct: 541 GTCSLFSREILNLTWWPLFRDVSFYILDLIMLILFFLDSLIAWWESLLLLLAYAFYVFTM 600
Query: 601 KWNKHIEVWVKEQLSRRPVAKVMALEDLSKPGDGAIAVDELQDNKKLKLPSLLTRGSSST 660
KWNKHIEVWVKEQLSRRPVAKVMALEDLSKPGDGAIAVDELQDNKKLKLPSLLTRGSSST
Sbjct: 601 KWNKHIEVWVKEQLSRRPVAKVMALEDLSKPGDGAIAVDELQDNKKLKLPSLLTRGSSST 660
Query: 661 SLHNSTIRSTIYQLMLHSLDPLREVRLAKEKEEESLNQGARAQPQAKAESKPEEEEPAKL 720
SLHNSTIRSTIYQLMLHSLDPLREVRLAKEKEEESLNQGARAQPQAKAESKPEEEEPAKL
Sbjct: 661 SLHNSTIRSTIYQLMLHSLDPLREVRLAKEKEEESLNQGARAQPQAKAESKPEEEEPAKL 720
Query: 721 PAVTVTPAPVPDIKGDQKENPGGQEDVAEAESTGEMPGEEGETAGEGETEEKSGGETQPE 780
PAVTVTPAPVPDIKGDQKENPGGQEDVAEAESTGEMPGEEGETAGEGETEEKSGGETQPE
Sbjct: 721 PAVTVTPAPVPDIKGDQKENPGGQEDVAEAESTGEMPGEEGETAGEGETEEKSGGETQPE 780
Query: 781 GEGETETQGKGEECEDENEAEGKGDNEGEDEGEIHAEDGEMKGNEGETESQELSAENHGE 840
GEGETETQGKGEECEDENEAEGKGDNEGEDEGEIHAEDGEMKGNEGETESQELSAENHGE
Sbjct: 781 GEGETETQGKGEECEDENEAEGKGDNEGEDEGEIHAEDGEMKGNEGETESQELSAENHGE 840
Query: 841 AKNDEKGVEDGGGSDGGDSEEEEEEEEEQEEEEEEEEQEEEEEEEEEEEEKGNEEPLSLD 900
AKNDEKGVEDGGGSDGGDSEEEEEEEEEQEEEEEEEEQEEEEEEEEEEEEKGNEEPLSLD
Sbjct: 841 AKNDEKGVEDGGGSDGGDSEEEEEEEEEQEEEEEEEEQEEEEEEEEEEEEKGNEEPLSLD 900
Query: 901 WPETRQKQAIYLFLLPIVFPLWLTVPDVRRQESRKFFVFTFLGSIMWIAMFSYLMVWWAH 960
WPETRQKQAIYLFLLPIVFPLWLTVPDVRRQESRKFFVFTFLGSIMWIAMFSYLMVWWAH
Sbjct: 901 WPETRQKQAIYLFLLPIVFPLWLTVPDVRRQESRKFFVFTFLGSIMWIAMFSYLMVWWAH 960
Query: 961 QVGETIGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPV 1020
QVGETIGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPV
Sbjct: 961 QVGETIGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPV 1020
Query: 1021 PWLLFSLINGLQPVPVSSNGLFCAIVLLFLMLLFVISSIASCKWRMNKILGFTMFLLYFV 1080
PWLLFSLINGLQPVPVSSNGLFCAIVLLFLMLLFVISSIASCKWRMNKILGFTMFLLYFV
Sbjct: 1021 PWLLFSLINGLQPVPVSSNGLFCAIVLLFLMLLFVISSIASCKWRMNKILGFTMFLLYFV 1080
Query: 1081 FLIISVMLEDRIISCPVSV 1099
FLIISVMLEDRIISCPVSV
Sbjct: 1081 FLIISVMLEDRIISCPVSV 1099
>gi|9966787 solute carrier family 24 (sodium/potassium/calcium
exchanger), member 2 [Homo sapiens]
Length = 661
Score = 346 bits (888), Expect = 6e-95
Identities = 192/351 (54%), Positives = 241/351 (68%), Gaps = 17/351 (4%)
Query: 435 HPKGEYPPDLFSVEERRQGWVVLHVFGMMYVFVALAIVCDEYFVPALGVITDKLQISEDV 494
H +G+YP D+FS+EERR+G ++LHV GM+Y+F+ALAIVCDE+FVP+L VIT+KL IS+DV
Sbjct: 115 HAQGDYPKDIFSLEERRKGAIILHVIGMIYMFIALAIVCDEFFVPSLTVITEKLGISDDV 174
Query: 495 AGATFMAAGGSAPELFTSLIGVFISHSNVGIGTIVGSAVFNILFVIGTCSLFSREILNLT 554
AGATFMAAGGSAPELFTSLIGVFI+HSNVGIGTIVGSAVFNILFVIG C+LFSREILNLT
Sbjct: 175 AGATFMAAGGSAPELFTSLIGVFIAHSNVGIGTIVGSAVFNILFVIGMCALFSREILNLT 234
Query: 555 WWPLFRDVSFYILDLIMLILFFLDSLIAWWESLLLLLAYAFYVFTMKWNKHIEVWVKEQL 614
WWPLFRDVSFYI+DLIMLI+FFLD++I WWESLLLL AY YV MK+N +E WVK+ +
Sbjct: 235 WWPLFRDVSFYIVDLIMLIIFFLDNVIMWWESLLLLTAYFCYVVFMKFNVQVEKWVKQMI 294
Query: 615 SRRPVAKVMALEDLSKPGDGAIAVDELQDNKKLKLPSLLTRGSSSTSLHNSTIRSTIYQL 674
+R V KV A E +KP + A D +D L L RG SS SLHNS +R++I+QL
Sbjct: 295 NRNKVVKVTAPEAQAKP---SAARD--KDEPTLPAKPRLQRGGSSASLHNSLMRNSIFQL 349
Query: 675 MLHSLDPLREV--RLAKEKEEESLNQGARAQPQ-------AKAESKPEEEEPAKLPAVTV 725
M+H+LDPL E K K +++ + R + + AK + +E E A V
Sbjct: 350 MIHTLDPLAEELGSYGKLKYYDTMTEEGRFREKASILHKIAKKKCHVDENERQNGAANHV 409
Query: 726 TPAPVPDIKGDQKE---NPGGQEDVAEAESTGEMPGEEGETAGEGETEEKS 773
+P+ E + E V + + G E +TA E E + S
Sbjct: 410 EKIELPNSTSTDVEMTPSSDASEPVQNGNLSHNIEGAEAQTADEEEDQPLS 460
Score = 343 bits (881), Expect = 4e-94
Identities = 175/262 (66%), Positives = 203/262 (77%), Gaps = 3/262 (1%)
Query: 838 HGEAKNDEKGVEDGGGSDGGDSEEEEEEEEEQEEEEEEEEQEEEEEEEEEEEEKGNEEPL 897
+G A + EK S + + E + E E + +EEE ++PL
Sbjct: 403 NGAANHVEKIELPNSTSTDVEMTPSSDASEPVQNGNLSHNIEGAEAQTADEEE---DQPL 459
Query: 898 SLDWPETRQKQAIYLFLLPIVFPLWLTVPDVRRQESRKFFVFTFLGSIMWIAMFSYLMVW 957
SL WP +KQ +L + PIVFPLW+T+PDVR+ SRKFF TF GSI WIA+FSYLMVW
Sbjct: 460 SLAWPSETRKQVTFLIVFPIVFPLWITLPDVRKPSSRKFFPITFFGSITWIAVFSYLMVW 519
Query: 958 WAHQVGETIGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVG 1017
WAHQVGETIGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVG
Sbjct: 520 WAHQVGETIGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVG 579
Query: 1018 LPVPWLLFSLINGLQPVPVSSNGLFCAIVLLFLMLLFVISSIASCKWRMNKILGFTMFLL 1077
LP+PWLL+++I+ QPV VSSNGLFCAIVLLF+MLLFVI SIA CKWRMNKILGF MF L
Sbjct: 580 LPLPWLLYTVIHRFQPVAVSSNGLFCAIVLLFIMLLFVILSIALCKWRMNKILGFIMFGL 639
Query: 1078 YFVFLIISVMLEDRIISCPVSV 1099
YFVFL++SV+LEDRI++CPVS+
Sbjct: 640 YFVFLVVSVLLEDRILTCPVSI 661
Score = 52.8 bits (125), Expect = 2e-06
Identities = 37/128 (28%), Positives = 66/128 (51%), Gaps = 4/128 (3%)
Query: 962 VGETIGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPVP 1021
+ E +GIS+++ G T +AAG S P+L TS+I ++ + + VGS +F+I + +
Sbjct: 164 ITEKLGISDDVAGATFMAAGGSAPELFTSLIGVFIAHSNVGIGTIVGSAVFNILFVIGMC 223
Query: 1022 WLLFSLINGLQPVPVSSNGLFCAIVLLFLMLLFVISSIASCKWRMNKILGFTMFLLYFVF 1081
L I L P+ + F + L+ L++ F+ + I W +L T + Y VF
Sbjct: 224 ALFSREILNLTWWPLFRDVSFYIVDLIMLIIFFLDNVI---MW-WESLLLLTAYFCYVVF 279
Query: 1082 LIISVMLE 1089
+ +V +E
Sbjct: 280 MKFNVQVE 287
Score = 39.7 bits (91), Expect = 0.016
Identities = 19/53 (35%), Positives = 33/53 (62%)
Query: 484 ITDKLQISEDVAGATFMAAGGSAPELFTSLIGVFISHSNVGIGTIVGSAVFNI 536
+ + + ISE++ G T +AAG S P+L TS+I ++ + + VGS +F+I
Sbjct: 524 VGETIGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDI 576
>gi|29788985 solute carrier family 24 member 4 isoform 2 precursor
[Homo sapiens]
Length = 586
Score = 222 bits (566), Expect = 1e-57
Identities = 129/329 (39%), Positives = 194/329 (58%), Gaps = 26/329 (7%)
Query: 432 PDLHPKGEYPPDLFSVEERRQGWVVLHVFGMMYVFVALAIVCDEYFVPALGVITDKLQIS 491
P +H E+P DLFS +ER+ G V+LH+ G +Y+F ALAIVCD++FVP+L I ++L +S
Sbjct: 63 PAIH---EFPTDLFSNKERQHGAVLLHILGALYMFYALAIVCDDFFVPSLEKICERLHLS 119
Query: 492 EDVAGATFMAAGGSAPELFTSLIGVFISHSNVGIGTIVGSAVFNILFVIGTCSLFSREIL 551
EDVAGATFMAAG S PELF S+IGVFI+H +VG+GTIVGSAVFNIL +IG C LF+ +++
Sbjct: 120 EDVAGATFMAAGSSTPELFASVIGVFITHGDVGVGTIVGSAVFNILCIIGVCGLFAGQVV 179
Query: 552 NLTWWPLFRDVSFYILDLIMLILFFLDSLIAWWESLLLLLAYAFYVFTMKWNKHIEVWV- 610
LTWW + RD +Y + +I+LI+F D I WWE L+L++ Y FY+ MK+N ++ +
Sbjct: 180 RLTWWAVCRDSVYYTISVIVLIVFIYDEQIVWWEGLVLIILYVFYILIMKYNVKMQAFFT 239
Query: 611 ---KEQLSRRPV-AKVMALEDLSKPG-DGAIAVDELQDNK--KLKLPSLLTR-------G 656
K + PV +++ A+++ + G + + VDE+ + K P R G
Sbjct: 240 VKQKSIANGNPVNSELEAVKEKPQYGKNPVVMVDEIMSSSPPKFTFPEAGLRIMITNKFG 299
Query: 657 SSSTSLHNSTIRSTIYQLMLHSLDPLREVRLAKEKEEESLNQGARAQ----PQAKAESKP 712
+ S I Q +++S + + L + E N + PQ E +P
Sbjct: 300 PRTRLRMASRIIINERQRLINSANGVSSKPLQNGRHENIENGNVPVENPEDPQQNQEQQP 359
Query: 713 EEE----EPAKLPAVTVTPAPVPDIKGDQ 737
+ EP + A ++P VP+ +GD+
Sbjct: 360 PPQPPPPEPEPVEADFLSPFSVPEARGDK 388
Score = 184 bits (466), Expect = 5e-46
Identities = 95/244 (38%), Positives = 149/244 (61%), Gaps = 7/244 (2%)
Query: 858 DSEEEEEEEEEQEEEEEEEEQEEEEEEEEEEEEKGNEEPLSLDW------PETRQKQAIY 911
+ E E E E+ Q+ +E++ + EP+ D+ PE R + +
Sbjct: 332 NGRHENIENGNVPVENPEDPQQNQEQQPPPQPPPPEPEPVEADFLSPFSVPEARGDKVKW 391
Query: 912 LFLLPIVFPLWLTVPDVRRQESRKFFVFTFLGSIMWIAMFSYLMVWWAHQVGETIGISEE 971
+F P++F L +T+P+ + KFF+ TF+ + +WIA+FSY+MVW +G T+GI +
Sbjct: 392 VFTWPLIFLLCVTIPNCSKPRWEKFFMVTFITATLWIAVFSYIMVWLVTIIGYTLGIPDV 451
Query: 972 IMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPVPW-LLFSLING 1030
IMG+T LAAGTS+PD + S+IVAR+GLGDMAVS+++GSN+FDI VGL VPW L ++N
Sbjct: 452 IMGITFLAAGTSVPDCMASLIVARQGLGDMAVSNTIGSNVFDILVGLGVPWGLQTMVVNY 511
Query: 1031 LQPVPVSSNGLFCAIVLLFLMLLFVISSIASCKWRMNKILGFTMFLLYFVFLIISVMLED 1090
V ++S GL ++VLL + + I KWR+++ LG + +LY +FL S+M+E
Sbjct: 512 GSTVKINSRGLVYSVVLLLGSVALTVLGIHLNKWRLDRKLGVYVLVLYAIFLCFSIMIEF 571
Query: 1091 RIIS 1094
+ +
Sbjct: 572 NVFT 575
Score = 48.1 bits (113), Expect = 4e-05
Identities = 34/124 (27%), Positives = 61/124 (49%), Gaps = 7/124 (5%)
Query: 961 QVGETIGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPV 1020
++ E + +SE++ G T +AAG+S P+L SVI GD+ V + VGS +F+I + V
Sbjct: 111 KICERLHLSEDVAGATFMAAGSSTPELFASVIGVFITHGDVGVGTIVGSAVFNILCIIGV 170
Query: 1021 PWLLFSLINGLQPVPVSSNGLFCAIVLLFLMLLFVISSIASCKWRMNKILGFTMFLLYFV 1080
L + L V + ++ I ++ L++ I W G + +LY
Sbjct: 171 CGLFAGQVVRLTWWAVCRDSVYYTISVIVLIVFIYDEQIV--WWE-----GLVLIILYVF 223
Query: 1081 FLII 1084
+++I
Sbjct: 224 YILI 227
Score = 38.5 bits (88), Expect = 0.035
Identities = 26/83 (31%), Positives = 41/83 (49%), Gaps = 1/83 (1%)
Query: 460 FGMMYVFVALAIVCDEYFVPAL-GVITDKLQISEDVAGATFMAAGGSAPELFTSLIGVFI 518
F + ++ L I Y + L +I L I + + G TF+AAG S P+ SLI
Sbjct: 417 FMVTFITATLWIAVFSYIMVWLVTIIGYTLGIPDVIMGITFLAAGTSVPDCMASLIVARQ 476
Query: 519 SHSNVGIGTIVGSAVFNILFVIG 541
++ + +GS VF+IL +G
Sbjct: 477 GLGDMAVSNTIGSNVFDILVGLG 499
>gi|29788987 solute carrier family 24 member 4 isoform 3 [Homo
sapiens]
Length = 558
Score = 215 bits (548), Expect = 2e-55
Identities = 131/348 (37%), Positives = 191/348 (54%), Gaps = 45/348 (12%)
Query: 432 PDLHPKGEYPPDLFSVEERRQGWVVLHVFGMMYVFVALAIVCDEYFVPALGVITDKLQIS 491
P +H E+P DLFS +ER+ G V+LH+ G +Y+F ALAIVCD++FVP+L I ++L +S
Sbjct: 16 PAIH---EFPTDLFSNKERQHGAVLLHILGALYMFYALAIVCDDFFVPSLEKICERLHLS 72
Query: 492 EDVAGATFMAAGGSAPELFTSLIGVFISHSNVGIGTIVGSAVFNILFVIGTCSLFSREIL 551
EDVAGATFMAAG S PELF S+IGVFI+H +VG+GTIVGSAVFNIL +IG C LF+ +++
Sbjct: 73 EDVAGATFMAAGSSTPELFASVIGVFITHGDVGVGTIVGSAVFNILCIIGVCGLFAGQVV 132
Query: 552 NLTWWPLFRDVSFYILDLIMLILFFLDSLIAWWESLLLLLAYAFYVFTMKWNKHIEVWV- 610
LTWW + RD +Y + +I+LI+F D I WWE L+L++ Y FY+ MK+N ++ +
Sbjct: 133 RLTWWAVCRDSVYYTISVIVLIVFIYDEQIVWWEGLVLIILYVFYILIMKYNVKMQAFFT 192
Query: 611 ---KEQLSRRPVAKVM---------ALEDLSKPGDG------------AIAVDELQDNK- 645
K + PV + + +D S P G + VDE+ +
Sbjct: 193 VKQKSIANGNPVNSELEAGNDFYDGSYDDPSVPLLGQVKEKPQYGKNPVVMVDEIMSSSP 252
Query: 646 -KLKLPSLLTR-------GSSSTSLHNSTIRSTIYQLMLHSLDPLREVRLAKEKEEESLN 697
K P R G + S I Q +++S + + L + E N
Sbjct: 253 PKFTFPEAGLRIMITNKFGPRTRLRMASRIIINERQRLINSANGVSSKPLQNGRHENIEN 312
Query: 698 QGARAQ----PQAKAESKPEEE----EPAKLPAVTVTPAPVPDIKGDQ 737
+ PQ E +P + EP + A ++P VP+ +GD+
Sbjct: 313 GNVPVENPEDPQQNQEQQPPPQPPPPEPEPVEADFLSPFSVPEARGDK 360
Score = 184 bits (466), Expect = 5e-46
Identities = 95/244 (38%), Positives = 149/244 (61%), Gaps = 7/244 (2%)
Query: 858 DSEEEEEEEEEQEEEEEEEEQEEEEEEEEEEEEKGNEEPLSLDW------PETRQKQAIY 911
+ E E E E+ Q+ +E++ + EP+ D+ PE R + +
Sbjct: 304 NGRHENIENGNVPVENPEDPQQNQEQQPPPQPPPPEPEPVEADFLSPFSVPEARGDKVKW 363
Query: 912 LFLLPIVFPLWLTVPDVRRQESRKFFVFTFLGSIMWIAMFSYLMVWWAHQVGETIGISEE 971
+F P++F L +T+P+ + KFF+ TF+ + +WIA+FSY+MVW +G T+GI +
Sbjct: 364 VFTWPLIFLLCVTIPNCSKPRWEKFFMVTFITATLWIAVFSYIMVWLVTIIGYTLGIPDV 423
Query: 972 IMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPVPW-LLFSLING 1030
IMG+T LAAGTS+PD + S+IVAR+GLGDMAVS+++GSN+FDI VGL VPW L ++N
Sbjct: 424 IMGITFLAAGTSVPDCMASLIVARQGLGDMAVSNTIGSNVFDILVGLGVPWGLQTMVVNY 483
Query: 1031 LQPVPVSSNGLFCAIVLLFLMLLFVISSIASCKWRMNKILGFTMFLLYFVFLIISVMLED 1090
V ++S GL ++VLL + + I KWR+++ LG + +LY +FL S+M+E
Sbjct: 484 GSTVKINSRGLVYSVVLLLGSVALTVLGIHLNKWRLDRKLGVYVLVLYAIFLCFSIMIEF 543
Query: 1091 RIIS 1094
+ +
Sbjct: 544 NVFT 547
Score = 48.1 bits (113), Expect = 4e-05
Identities = 34/124 (27%), Positives = 61/124 (49%), Gaps = 7/124 (5%)
Query: 961 QVGETIGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPV 1020
++ E + +SE++ G T +AAG+S P+L SVI GD+ V + VGS +F+I + V
Sbjct: 64 KICERLHLSEDVAGATFMAAGSSTPELFASVIGVFITHGDVGVGTIVGSAVFNILCIIGV 123
Query: 1021 PWLLFSLINGLQPVPVSSNGLFCAIVLLFLMLLFVISSIASCKWRMNKILGFTMFLLYFV 1080
L + L V + ++ I ++ L++ I W G + +LY
Sbjct: 124 CGLFAGQVVRLTWWAVCRDSVYYTISVIVLIVFIYDEQIV--WWE-----GLVLIILYVF 176
Query: 1081 FLII 1084
+++I
Sbjct: 177 YILI 180
Score = 38.5 bits (88), Expect = 0.035
Identities = 26/83 (31%), Positives = 41/83 (49%), Gaps = 1/83 (1%)
Query: 460 FGMMYVFVALAIVCDEYFVPAL-GVITDKLQISEDVAGATFMAAGGSAPELFTSLIGVFI 518
F + ++ L I Y + L +I L I + + G TF+AAG S P+ SLI
Sbjct: 389 FMVTFITATLWIAVFSYIMVWLVTIIGYTLGIPDVIMGITFLAAGTSVPDCMASLIVARQ 448
Query: 519 SHSNVGIGTIVGSAVFNILFVIG 541
++ + +GS VF+IL +G
Sbjct: 449 GLGDMAVSNTIGSNVFDILVGLG 471
>gi|24111228 solute carrier family 24 member 4 isoform 1 precursor
[Homo sapiens]
Length = 605
Score = 215 bits (548), Expect = 2e-55
Identities = 131/348 (37%), Positives = 191/348 (54%), Gaps = 45/348 (12%)
Query: 432 PDLHPKGEYPPDLFSVEERRQGWVVLHVFGMMYVFVALAIVCDEYFVPALGVITDKLQIS 491
P +H E+P DLFS +ER+ G V+LH+ G +Y+F ALAIVCD++FVP+L I ++L +S
Sbjct: 63 PAIH---EFPTDLFSNKERQHGAVLLHILGALYMFYALAIVCDDFFVPSLEKICERLHLS 119
Query: 492 EDVAGATFMAAGGSAPELFTSLIGVFISHSNVGIGTIVGSAVFNILFVIGTCSLFSREIL 551
EDVAGATFMAAG S PELF S+IGVFI+H +VG+GTIVGSAVFNIL +IG C LF+ +++
Sbjct: 120 EDVAGATFMAAGSSTPELFASVIGVFITHGDVGVGTIVGSAVFNILCIIGVCGLFAGQVV 179
Query: 552 NLTWWPLFRDVSFYILDLIMLILFFLDSLIAWWESLLLLLAYAFYVFTMKWNKHIEVWV- 610
LTWW + RD +Y + +I+LI+F D I WWE L+L++ Y FY+ MK+N ++ +
Sbjct: 180 RLTWWAVCRDSVYYTISVIVLIVFIYDEQIVWWEGLVLIILYVFYILIMKYNVKMQAFFT 239
Query: 611 ---KEQLSRRPVAKVM---------ALEDLSKPGDG------------AIAVDELQDNK- 645
K + PV + + +D S P G + VDE+ +
Sbjct: 240 VKQKSIANGNPVNSELEAGNDFYDGSYDDPSVPLLGQVKEKPQYGKNPVVMVDEIMSSSP 299
Query: 646 -KLKLPSLLTR-------GSSSTSLHNSTIRSTIYQLMLHSLDPLREVRLAKEKEEESLN 697
K P R G + S I Q +++S + + L + E N
Sbjct: 300 PKFTFPEAGLRIMITNKFGPRTRLRMASRIIINERQRLINSANGVSSKPLQNGRHENIEN 359
Query: 698 QGARAQ----PQAKAESKPEEE----EPAKLPAVTVTPAPVPDIKGDQ 737
+ PQ E +P + EP + A ++P VP+ +GD+
Sbjct: 360 GNVPVENPEDPQQNQEQQPPPQPPPPEPEPVEADFLSPFSVPEARGDK 407
Score = 184 bits (466), Expect = 5e-46
Identities = 95/244 (38%), Positives = 149/244 (61%), Gaps = 7/244 (2%)
Query: 858 DSEEEEEEEEEQEEEEEEEEQEEEEEEEEEEEEKGNEEPLSLDW------PETRQKQAIY 911
+ E E E E+ Q+ +E++ + EP+ D+ PE R + +
Sbjct: 351 NGRHENIENGNVPVENPEDPQQNQEQQPPPQPPPPEPEPVEADFLSPFSVPEARGDKVKW 410
Query: 912 LFLLPIVFPLWLTVPDVRRQESRKFFVFTFLGSIMWIAMFSYLMVWWAHQVGETIGISEE 971
+F P++F L +T+P+ + KFF+ TF+ + +WIA+FSY+MVW +G T+GI +
Sbjct: 411 VFTWPLIFLLCVTIPNCSKPRWEKFFMVTFITATLWIAVFSYIMVWLVTIIGYTLGIPDV 470
Query: 972 IMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPVPW-LLFSLING 1030
IMG+T LAAGTS+PD + S+IVAR+GLGDMAVS+++GSN+FDI VGL VPW L ++N
Sbjct: 471 IMGITFLAAGTSVPDCMASLIVARQGLGDMAVSNTIGSNVFDILVGLGVPWGLQTMVVNY 530
Query: 1031 LQPVPVSSNGLFCAIVLLFLMLLFVISSIASCKWRMNKILGFTMFLLYFVFLIISVMLED 1090
V ++S GL ++VLL + + I KWR+++ LG + +LY +FL S+M+E
Sbjct: 531 GSTVKINSRGLVYSVVLLLGSVALTVLGIHLNKWRLDRKLGVYVLVLYAIFLCFSIMIEF 590
Query: 1091 RIIS 1094
+ +
Sbjct: 591 NVFT 594
Score = 48.1 bits (113), Expect = 4e-05
Identities = 34/124 (27%), Positives = 61/124 (49%), Gaps = 7/124 (5%)
Query: 961 QVGETIGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPV 1020
++ E + +SE++ G T +AAG+S P+L SVI GD+ V + VGS +F+I + V
Sbjct: 111 KICERLHLSEDVAGATFMAAGSSTPELFASVIGVFITHGDVGVGTIVGSAVFNILCIIGV 170
Query: 1021 PWLLFSLINGLQPVPVSSNGLFCAIVLLFLMLLFVISSIASCKWRMNKILGFTMFLLYFV 1080
L + L V + ++ I ++ L++ I W G + +LY
Sbjct: 171 CGLFAGQVVRLTWWAVCRDSVYYTISVIVLIVFIYDEQIV--WWE-----GLVLIILYVF 223
Query: 1081 FLII 1084
+++I
Sbjct: 224 YILI 227
Score = 38.5 bits (88), Expect = 0.035
Identities = 26/83 (31%), Positives = 41/83 (49%), Gaps = 1/83 (1%)
Query: 460 FGMMYVFVALAIVCDEYFVPAL-GVITDKLQISEDVAGATFMAAGGSAPELFTSLIGVFI 518
F + ++ L I Y + L +I L I + + G TF+AAG S P+ SLI
Sbjct: 436 FMVTFITATLWIAVFSYIMVWLVTIIGYTLGIPDVIMGITFLAAGTSVPDCMASLIVARQ 495
Query: 519 SHSNVGIGTIVGSAVFNILFVIG 541
++ + +GS VF+IL +G
Sbjct: 496 GLGDMAVSNTIGSNVFDILVGLG 518
>gi|31563526 solute carrier family 24 (sodium/potassium/calcium
exchanger), member 3 [Homo sapiens]
Length = 644
Score = 209 bits (533), Expect = 9e-54
Identities = 136/347 (39%), Positives = 198/347 (57%), Gaps = 15/347 (4%)
Query: 432 PDLHPKGEYPPDLFSVEERRQGWVVLHVFGMMYVFVALAIVCDEYFVPALGVITDKLQIS 491
P LH E+P D+F+ E+RRQG VVLHV +Y+F ALAIVCD++FVP+L I ++L +S
Sbjct: 90 PALH---EFPNDIFTNEDRRQGAVVLHVLCAIYMFYALAIVCDDFFVPSLEKICERLHLS 146
Query: 492 EDVAGATFMAAGGSAPELFTSLIGVFISHSNVGIGTIVGSAVFNILFVIGTCSLFSREIL 551
EDVAGATFMAAG SAPELFTS+IGVFI+ +VG+GTIVGSAVFNIL +IG C LF+ +++
Sbjct: 147 EDVAGATFMAAGSSAPELFTSVIGVFITKGDVGVGTIVGSAVFNILCIIGVCGLFAGQVV 206
Query: 552 NLTWWPLFRDVSFYILDLIMLILFFLDSLIAWWESLLLLLAYAFYVFTMKWNKHIEVWVK 611
L+ W L RD +Y L +I LI+F D ++WWESL+L+L Y Y+ MK+N I +
Sbjct: 207 ALSSWCLLRDSIYYTLSVIALIVFIYDEKVSWWESLVLVLMYLIYIVIMKYNACIHQCFE 266
Query: 612 EQLSR-----RPVAKVMALEDLSKPGDGAIAVDELQDNKKLKLPSLLTRGSSSTSLHNST 666
+ +A ++D S + + + ++K + ++ S H +
Sbjct: 267 RRTKGAGNMVNGLANNAEIDDSSNCDATVVLLKKANFHRKASV--IMVDELLSAYPHQLS 324
Query: 667 IRSTIYQLMLHSLDPLREVRLAKEKEEESLNQGARAQPQAKAESKPEEEEPAKLPAV-TV 725
++M+ S P + RL+ +N+ R ++A + E E K+P TV
Sbjct: 325 FSEAGLRIMITSHFP-PKTRLSM-ASRMLINERQRL-INSRAYTNGESEVAIKIPIKHTV 381
Query: 726 TPAPVPDIKGDQKENPGGQED-VAEAESTGEMPGEEGETAGEGETEE 771
P D+ N ++D VAEA + E E+ E E E +E
Sbjct: 382 ENGTGPSSAPDRGVNGTRRDDVVAEAGNETENENEDNENDEEEEEDE 428
Score = 188 bits (477), Expect = 3e-47
Identities = 97/243 (39%), Positives = 151/243 (62%), Gaps = 3/243 (1%)
Query: 853 GSDGGDSEEEEEEEEEQEEEEEEEEQEEEEEEEEEEEEKGNEEPLSLDWPETRQKQAIYL 912
G +G ++ E + E E E+ + +EEEEE+E++++G P D P + + +
Sbjct: 394 GVNGTRRDDVVAEAGNETENENEDNENDEEEEEDEDDDEGPYTPF--DTPSGKLETVKWA 451
Query: 913 FLLPIVFPLWLTVPDVRRQESRKFFVFTFLGSIMWIAMFSYLMVWWAHQVGETIGISEEI 972
F P+ F L+ TVP+ + K+F+ TF S +WIA FSY+MVW +G T+GI + I
Sbjct: 452 FTWPLSFVLYFTVPNCNKPRWEKWFMVTFASSTLWIAAFSYMMVWMVTIIGYTLGIPDVI 511
Query: 973 MGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPVPWLLFSL-INGL 1031
MG+T LAAGTS+PD + S+IVAR+G+GDMAVS+S+GSN+FDI +GL +PW L +L ++
Sbjct: 512 MGITFLAAGTSVPDCMASLIVARQGMGDMAVSNSIGSNVFDILIGLGLPWALQTLAVDYG 571
Query: 1032 QPVPVSSNGLFCAIVLLFLMLLFVISSIASCKWRMNKILGFTMFLLYFVFLIISVMLEDR 1091
+ ++S GL ++ LL + + + KW+++K LG LLY VFL S+M E
Sbjct: 572 SYIRLNSRGLIYSVGLLLASVFVTVFGVHLNKWQLDKKLGCGCLLLYGVFLCFSIMTEFN 631
Query: 1092 IIS 1094
+ +
Sbjct: 632 VFT 634
Score = 50.4 bits (119), Expect = 9e-06
Identities = 33/122 (27%), Positives = 64/122 (52%), Gaps = 4/122 (3%)
Query: 961 QVGETIGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPV 1020
++ E + +SE++ G T +AAG+S P+L TSVI GD+ V + VGS +F+I + V
Sbjct: 138 KICERLHLSEDVAGATFMAAGSSAPELFTSVIGVFITKGDVGVGTIVGSAVFNILCIIGV 197
Query: 1021 PWLLFSLINGLQPVPVSSNGLFCAIVLLFLMLLFVISSIASCKWRMNKILGFTMFLLYFV 1080
L + L + + ++ + ++ L++ ++ W + +L M+L+Y V
Sbjct: 198 CGLFAGQVVALSSWCLLRDSIYYTLSVIALIVFIYDEKVS---WWESLVL-VLMYLIYIV 253
Query: 1081 FL 1082
+
Sbjct: 254 IM 255
Score = 38.5 bits (88), Expect = 0.035
Identities = 21/59 (35%), Positives = 32/59 (54%)
Query: 483 VITDKLQISEDVAGATFMAAGGSAPELFTSLIGVFISHSNVGIGTIVGSAVFNILFVIG 541
+I L I + + G TF+AAG S P+ SLI ++ + +GS VF+IL +G
Sbjct: 500 IIGYTLGIPDVIMGITFLAAGTSVPDCMASLIVARQGMGDMAVSNSIGSNVFDILIGLG 558
>gi|45504369 solute carrier family 24, member 5 [Homo sapiens]
Length = 500
Score = 169 bits (429), Expect = 1e-41
Identities = 84/203 (41%), Positives = 130/203 (64%), Gaps = 9/203 (4%)
Query: 413 TALLPEELSPSPSVLPPSLPD-----LHPKGEYPPDLFSVEERRQGWVVLHVFGMMYVFV 467
TA LP + P LP + + + P E+P F+ +ERR G ++++ ++Y+F+
Sbjct: 22 TAHLPLSGTSLPQRLPRATGNSTQCVISPSSEFPEGFFTRQERRDGGIIIYFLIIVYMFM 81
Query: 468 ALAIVCDEYFVPALGVITDKLQISEDVAGATFMAAGGSAPELFTSLIGVFISHSNVGIGT 527
A++IVCDEYF+P+L +I++ L +S+DVAG TFMAAG SAPEL T+ +GVFI+ ++GI T
Sbjct: 82 AISIVCDEYFLPSLEIISESLGLSQDVAGTTFMAAGSSAPELVTAFLGVFITKGDIGIST 141
Query: 528 IVGSAVFNILFVIGTCSLFSREILNLTWWPLFRDVSFYILDLIMLILFFLDSLIAWWESL 587
I+GSA++N+L + C L S + L+ WPLFRD + Y + ++ D+ + W+E
Sbjct: 142 ILGSAIYNLLGICAACGLLSNTVSTLSCWPLFRDCAAYTISAAAVLGIIYDNQVYWYEGA 201
Query: 588 LLLLAYAFYV----FTMKWNKHI 606
LLLL Y YV F +K N++I
Sbjct: 202 LLLLIYGLYVLVLCFDIKINQYI 224
Score = 157 bits (397), Expect = 5e-38
Identities = 85/203 (41%), Positives = 130/203 (64%), Gaps = 3/203 (1%)
Query: 893 NEEPLSL-DWPETRQKQAIYLFLLPIVFPLWLTVPDVRRQESRKFFVFTFLGSIMWIAMF 951
+E+P S+ + PE K+ ++ LPI+ L+LT PD R++ + +FV TF S +WI+ F
Sbjct: 289 SEDPPSVFNMPEADLKRIFWVLSLPIITLLFLTTPDCRKKFWKNYFVITFFMSAIWISAF 348
Query: 952 SYLMVWWAHQVGETIGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNI 1011
+Y++VW GET+ I + +MGLT+LAAGTSIPD I SV+VARKG GDMA+S+ VGSN+
Sbjct: 349 TYILVWMVTITGETLEIPDTVMGLTLLAAGTSIPDTIASVLVARKGKGDMAMSNIVGSNV 408
Query: 1012 FDITVGLPVPWLL-FSLINGLQPVPVSSNGLFCAIVLLFLMLLFVISSIASCKWRMNKIL 1070
FD+ + L +PW + + ING P V+S GL + L + ++F+ ++ W++++ L
Sbjct: 409 FDM-LCLGIPWFIKTAFINGSAPAEVNSRGLTYITISLNISIIFLFLAVHFNGWKLDRKL 467
Query: 1071 GFTMFLLYFVFLIISVMLEDRII 1093
G L Y +SV+ E II
Sbjct: 468 GIVCLLSYLGLATLSVLYELGII 490
Score = 46.6 bits (109), Expect = 1e-04
Identities = 32/132 (24%), Positives = 65/132 (49%), Gaps = 4/132 (3%)
Query: 962 VGETIGISEEIMGLTILAAGTSIPDLITSVIVARKGLGDMAVSSSVGSNIFDITVGLPVP 1021
+ E++G+S+++ G T +AAG+S P+L+T+ + GD+ +S+ +GS I+++
Sbjct: 98 ISESLGLSQDVAGTTFMAAGSSAPELVTAFLGVFITKGDIGISTILGSAIYNLLGICAAC 157
Query: 1022 WLLFSLINGLQPVPVSSNGLFCAIVLLFLMLLFVISSIASCKWRMNKILGFTMFLLYFVF 1081
LL + ++ L P+ + CA + + I W +L ++ LY +
Sbjct: 158 GLLSNTVSTLSCWPLFRD---CAAYTISAAAVLGIIYDNQVYWYEGALL-LLIYGLYVLV 213
Query: 1082 LIISVMLEDRII 1093
L + + II
Sbjct: 214 LCFDIKINQYII 225
Score = 39.3 bits (90), Expect = 0.021
Identities = 37/137 (27%), Positives = 60/137 (43%), Gaps = 24/137 (17%)
Query: 425 SVLPPSLPDLHPKGEYPPDLFSVEE---RRQGWVVL--------------------HVFG 461
S L SL L E PP +F++ E +R WV+ + F
Sbjct: 276 SQLSISLHGLSQVSEDPPSVFNMPEADLKRIFWVLSLPIITLLFLTTPDCRKKFWKNYFV 335
Query: 462 MMYVFVALAIVCDEYFVPALGVIT-DKLQISEDVAGATFMAAGGSAPELFTSLIGVFISH 520
+ + A+ I Y + + IT + L+I + V G T +AAG S P+ S++
Sbjct: 336 ITFFMSAIWISAFTYILVWMVTITGETLEIPDTVMGLTLLAAGTSIPDTIASVLVARKGK 395
Query: 521 SNVGIGTIVGSAVFNIL 537
++ + IVGS VF++L
Sbjct: 396 GDMAMSNIVGSNVFDML 412
>gi|78190492 retinitis pigmentosa GTPase regulator isoform C [Homo
sapiens]
Length = 1152
Score = 126 bits (317), Expect = 1e-28
Identities = 88/214 (41%), Positives = 115/214 (53%), Gaps = 24/214 (11%)
Query: 689 KEKEEESLNQGARAQPQAKAESKPEEEEPAKLPAVTVTPAPVPDIKGDQKENPGGQEDVA 748
+EKEE +G + + K E + EEEE + +G+++E G +E
Sbjct: 806 EEKEEGGEVEGGEVE-EGKGEREEEEEEGE---------GEEEEGEGEEEEGEGEEE--- 852
Query: 749 EAESTGEMPGEEGETAGEGETEEKSGGETQPEGEGETETQGKGEECEDENEAEGKGDNEG 808
E E GE GEEGE EGE E G E + EGEGE E +G+GEE E EG+G+ EG
Sbjct: 853 EGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEE----EEGEGEGEEEG 908
Query: 809 EDEGEIHAED--GEMKGNEGETESQELSAENHGE----AKNDEKGVEDGGGSDG-GDSEE 861
E EGE + GE +G EGE E +E E GE +E+G +G +G G+ EE
Sbjct: 909 EGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGEDGEGEGEEEEGEWEGEEEEGEGEGEE 968
Query: 862 EEEEEEEQEEEEEEEEQEEEEEEEEEEEEKGNEE 895
E E E E+ E E EEE+ E E EEEE EE+G EE
Sbjct: 969 EGEGEGEEGEGEGEEEEGEGEGEEEEGEEEGEEE 1002
Score = 119 bits (299), Expect = 1e-26
Identities = 88/225 (39%), Positives = 115/225 (51%), Gaps = 17/225 (7%)
Query: 693 EESLNQGARAQPQAKAESKPEEEEPAKLPAVTVTPAPVPDIKGDQKENPGGQEDVAEAES 752
EE +G + + K E + EE E + + +G+ +E G+ + E E
Sbjct: 843 EEEEGEGEEEEGEGKGEEEGEEGEGEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEG 902
Query: 753 TGEMPGE------EGETAGEGETEEKSGGETQPEGEGETETQGKGEECEDENEAEGK--- 803
GE GE EGE GE E EE G + EGEGE E G+GE E+E E EG+
Sbjct: 903 EGEEEGEGEGEEEEGEGKGEEEGEEGEGEGEEEEGEGEGE-DGEGEGEEEEGEWEGEEEE 961
Query: 804 GDNEGEDEGEIHAEDGEMKGNEGETESQELSAENHGEAKNDEKGVEDGGGSDGGDSEEEE 863
G+ EGE+EGE E+GE +G E E E + E GE E+G E+G G + G+ E EE
Sbjct: 962 GEGEGEEEGEGEGEEGEGEGEEEEGEGE--GEEEEGE----EEGEEEGEGEEEGEGEGEE 1015
Query: 864 EEEEEQEEEEEEEEQEEEEEEEEEEEEKGNEEPLSLDWPETRQKQ 908
EEE E E E E EE E E EEEE EEE G E + E R+ +
Sbjct: 1016 EEEGEVEGEVEGEEGEGEGEEEEGEEE-GEEREKEGEGEENRRNR 1059
Score = 116 bits (290), Expect = 1e-25
Identities = 80/210 (38%), Positives = 110/210 (52%), Gaps = 30/210 (14%)
Query: 690 EKEEESLNQGARAQPQAKAESKPEEEEPAKLPAVTVTPAPVPDIKGDQKENPG-GQEDVA 748
E EEE +G + + K E + EE E +G+++E G G++
Sbjct: 903 EGEEEGEGEGEEEEGEGKGEEEGEEGEG----------------EGEEEEGEGEGEDGEG 946
Query: 749 EAEST-GEMPGEEGETAGEGETEEKSGGETQPEGEGETET---QGKGEECEDENEAEGKG 804
E E GE GEE E GEGE E + GE + EGEGE E +G+ EE E+E E EG+G
Sbjct: 947 EGEEEEGEWEGEEEEGEGEGEEEGEGEGE-EGEGEGEEEEGEGEGEEEEGEEEGEEEGEG 1005
Query: 805 DNEGEDEGEIHAE---DGEMKGNEGETESQELSAENHGEAKNDEKGVEDGGGSDGGDSEE 861
+ EGE EGE E +GE++G EGE E +E E GE + E G G + + E
Sbjct: 1006 EEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKE-----GEGEENRRNRE 1060
Query: 862 EEEEEEEQEEEEEEEEQEEEEEEEEEEEEK 891
EEEEEE + +E EEE E ++ EE ++ K
Sbjct: 1061 EEEEEEGKYQETGEEENERQDGEEYKKVSK 1090
Score = 112 bits (281), Expect = 1e-24
Identities = 87/238 (36%), Positives = 112/238 (47%), Gaps = 46/238 (19%)
Query: 686 RLAKEKEEESLNQGARAQPQAKAESKPEEEEPAKLPAVTVTPAPVPDIKGDQKENPGGQE 745
R +E+E++ QG + + + E EEE G+ +E G +E
Sbjct: 705 RDGEEQEQKEREQGHQKERNQEMEEGGEEEH------------------GEGEEEEGDRE 746
Query: 746 DVAEAESTGEMPGEEGETAGEGETEE------------KSGGETQPEGEGETE-TQGKGE 792
+ E E G+ GE E GE E EE + G E +GEGE E T+G+GE
Sbjct: 747 EEEEKEGEGKEEGEGEEVEGEREKEEGERKKEERAGKEEKGEEEGDQGEGEEEETEGRGE 806
Query: 793 ECEDENEAEGKGDNEGEDEGEIHAEDGEMKGNEGETESQELSAENH-GEAKNDEKGVEDG 851
E E+ E EG EG+ E E E+GE + EGE E +E E GE K +E+G E
Sbjct: 807 EKEEGGEVEGGEVEEGKGEREEEEEEGEGEEEEGEGEEEEGEGEEEEGEGKGEEEGEEGE 866
Query: 852 GGSDG-----------GDSEEEEEEEEEQEEEEEEEEQEEE---EEEEEEEEEKGNEE 895
G +G G+ E EEE E E EEEE E E EEE E EEEE E KG EE
Sbjct: 867 GEEEGEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGEGEEEGEGEGEEEEGEGKGEEE 924
Score = 105 bits (262), Expect = 2e-22
Identities = 82/210 (39%), Positives = 104/210 (49%), Gaps = 25/210 (11%)
Query: 689 KEKEEESLNQGARAQPQAKAESKPEEEEPAKLPAVTVTPAPVPDIKGDQKENPGGQEDVA 748
+EK E+ +G +P + E+EE K + +QKE G +
Sbjct: 674 REKGEKDKGRGEMERPGEGEKELAEKEEWKKRDGE----------EQEQKEREQGHQK-- 721
Query: 749 EAESTGEMPGEEGETAGEGETEEKSGGETQPEGEGETETQGKGEECEDENEAEGKGDNEG 808
E EM E GEGE EE+ E + E EGE + +G+GEE E E E E EG
Sbjct: 722 --ERNQEMEEGGEEEHGEGE-EEEGDREEEEEKEGEGKEEGEGEEVEGEREKE-----EG 773
Query: 809 EDEGEIHA---EDGEMKGNEGETESQELSAENHGEAKNDEKGVEDGGGSDGGDSEEEEEE 865
E + E A E GE +G++GE E +E E GE K + VE G +G EEEEE
Sbjct: 774 ERKKEERAGKEEKGEEEGDQGEGEEEE--TEGRGEEKEEGGEVEGGEVEEGKGEREEEEE 831
Query: 866 EEEQEEEEEEEEQEEEEEEEEEEEEKGNEE 895
E E EEEE E E+EE E EEEE E KG EE
Sbjct: 832 EGEGEEEEGEGEEEEGEGEEEEGEGKGEEE 861
Score = 70.1 bits (170), Expect = 1e-11
Identities = 78/322 (24%), Positives = 143/322 (44%), Gaps = 44/322 (13%)
Query: 622 VMALEDLSKPGDGAIAVDELQDNKKLKLPSLLTRGSSSTSLHNSTIRSTIYQLMLHSLDP 681
V++ +DL +P + +DE+ ++ S + +T + N T + + L+S +
Sbjct: 459 VLSEQDLMQPEEPDYLLDEMTKEAEIDNSSTVESLGETTDILNMT-----HIMSLNSNEK 513
Query: 682 -LREVRLAKEKEEESLNQGARAQPQAKAESKPEEEEPAKL------------------PA 722
L+ + K+K+++++ + + + + E EE +++ PA
Sbjct: 514 SLKLSPVQKQKKQQTIGELTQDTALTENDDSDEYEEMSEMKEGKACKQHVSQGIFMTQPA 573
Query: 723 VTVTP-----APVPDIKGDQKENPGG---QEDVAEAESTGEMPG---EEGETAGEGETE- 770
T+ +P+ K +++ G +++V E ++ G E+ E + T+
Sbjct: 574 TTIEAFSDEEVEIPEEKEGAEDSKGNGIEEQEVEANEENVKVHGGRKEKTEILSDDLTDK 633
Query: 771 -EKSGGETQPEGEGETETQGKGE-ECEDENEAEGKGDNEGEDEGEIHAEDGEM-KGNEGE 827
E S G+ + GE E +G+G+ CE+ + +E ++GE GEM + EGE
Sbjct: 634 AEVSEGKAKSVGEAEDGPEGRGDGTCEEGSSGAEHWQDEEREKGEKDKGRGEMERPGEGE 693
Query: 828 TESQELSAENHGEAKNDEKGVEDGGGSDGGDSEEEEEEEEEQEEEEEEEEQEE-EEEEEE 886
E AE K D + E G E +E EE EEE E E+EE + EEEE
Sbjct: 694 KEL----AEKEEWKKRDGEEQEQKEREQGHQKERNQEMEEGGEEEHGEGEEEEGDREEEE 749
Query: 887 EEEEKGNEEPLSLDWPETRQKQ 908
E+E +G EE + R+K+
Sbjct: 750 EKEGEGKEEGEGEEVEGEREKE 771
Score = 53.1 bits (126), Expect = 1e-06
Identities = 48/142 (33%), Positives = 64/142 (45%), Gaps = 28/142 (19%)
Query: 689 KEKEEESLNQGARAQPQAKAESKPEEEEPAKLPAVTVTPAPVPDIKGDQKENPGGQEDVA 748
+E E E +G + + E + EE E +G+++E E+
Sbjct: 960 EEGEGEGEEEGEGEGEEGEGEGEEEEGEG----------------EGEEEEGEEEGEEEG 1003
Query: 749 EAESTGEMPGEE---GETAGEGETEEKSGGETQPEGEGE-TET--QGKGEE----CEDEN 798
E E GE GEE GE GE E EE G + EGE E E +G+GEE E+E
Sbjct: 1004 EGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEEGEEEGEEREKEGEGEENRRNREEEE 1063
Query: 799 EAEGKGDNEGEDEGEIHAEDGE 820
E EGK GE+E E +DGE
Sbjct: 1064 EEEGKYQETGEEENE--RQDGE 1083
Score = 52.4 bits (124), Expect = 2e-06
Identities = 41/139 (29%), Positives = 67/139 (48%), Gaps = 26/139 (18%)
Query: 693 EESLNQGARAQPQAKAESKPEEEEPAKLPAVTVTPAPVPDIKGD-QKENPGGQEDVAEAE 751
EE +G + + + E + EEE + +G+ ++E G E+ E E
Sbjct: 975 EEGEGEGEEEEGEGEGEEEEGEEEGEE--------------EGEGEEEGEGEGEEEEEGE 1020
Query: 752 STGEMPGEEGE-----TAGEGETEEKSGGETQPEGEGETETQGKGEECEDENEAEGKGDN 806
GE+ GEEGE GE E EE+ + EGEGE + + EE E+E + + G+
Sbjct: 1021 VEGEVEGEEGEGEGEEEEGEEEGEER-----EKEGEGEENRRNREEEEEEEGKYQETGEE 1075
Query: 807 EGE-DEGEIHAEDGEMKGN 824
E E +GE + + ++KG+
Sbjct: 1076 ENERQDGEEYKKVSKIKGS 1094
Score = 35.4 bits (80), Expect = 0.30
Identities = 37/153 (24%), Positives = 56/153 (36%), Gaps = 47/153 (30%)
Query: 691 KEEESLNQGARAQPQAKAESKPEEEEPAKLPAVTVTPAPVP-DIKGDQKENPGGQEDVAE 749
+EEE +G + + + E + E EE + V +++G++ E G +E+
Sbjct: 982 EEEEGEGEGEEEEGEEEGEEEGEGEEEGEGEGEEEEEGEVEGEVEGEEGEGEGEEEE--- 1038
Query: 750 AESTGEMPGEEGETAGEGET-------EEKSGGETQPEGEGETE---------------- 786
GE GEE E GEGE EE+ G+ Q GE E E
Sbjct: 1039 ----GEEEGEEREKEGEGEENRRNREEEEEEEGKYQETGEEENERQDGEEYKKVSKIKGS 1094
Query: 787 ----------------TQGKGEECEDENEAEGK 803
TQG G+E + + K
Sbjct: 1095 VKYGKHKTYQKKSVTNTQGNGKEQRSKMPVQSK 1127
>gi|13540523 nucleosomal binding protein 1 [Homo sapiens]
Length = 282
Score = 93.2 bits (230), Expect = 1e-18
Identities = 67/227 (29%), Positives = 116/227 (51%), Gaps = 18/227 (7%)
Query: 683 REVRLAKEKEEESLNQGARAQPQAKAESKPEEE--EPAKLPAVTVTPAPVPDIKGDQKEN 740
R+++ + EE+++ A+A + K E+ EE+ E AK +T AP + + + +
Sbjct: 43 RKMKTKSDMMEENIDTSAQAVAETKQEAVVEEDYNENAKNGEAKITEAPASEKEIVEVK- 101
Query: 741 PGGQEDVAEA-ESTGEMPGEEGETAGEGETEEKSGGETQPEGEGETETQGKGEECEDENE 799
+E++ +A E GE E ++K E Q E +GE + K E+ E++ +
Sbjct: 102 ---EENIEDATEKGGEKKEAVAAEVKNEEEDQKEDEEDQNEEKGEAGKEDKDEKGEEDGK 158
Query: 800 AEGKGDNEGEDEGEIH----AEDGEMKGNEG----ETESQELSAENHGEAKNDEKGVEDG 851
+ G+ +GED E EDG+ G +G E E +E + G+ K +E G E G
Sbjct: 159 EDKNGNEKGEDAKEKEDGKKGEDGKGNGEDGKEKGEDEKEEEDRKETGDGKENEDGKEKG 218
Query: 852 GGSDGGD---SEEEEEEEEEQEEEEEEEEQEEEEEEEEEEEEKGNEE 895
+G D E+E+E E+ +E+E EE+ +E+E+ +EEE+G EE
Sbjct: 219 DKKEGKDVKVKEDEKEREDGKEDEGGNEEEAGKEKEDLKEEEEGKEE 265
>gi|17975763 myelin transcription factor 1 [Homo sapiens]
Length = 1121
Score = 88.6 bits (218), Expect = 3e-17
Identities = 71/205 (34%), Positives = 93/205 (45%), Gaps = 15/205 (7%)
Query: 692 EEESLNQGARAQPQAKAESKPEEEEPAKLPAVTVTPAPVPDIKGDQKENPGGQEDVAEAE 751
E E +GA A+ + E E + P +K NP G A A
Sbjct: 107 ESEGTLEGAEAETSGQDEIHRPETAEGRSP-----------VKSHFGSNPIGS---ATAS 152
Query: 752 STGEMPGEEGETAGEGETEEKSGGETQPEGE-GETETQGKGEECEDENEAEGKGDNEGED 810
S G +G A + ET E + G+ G G + AEG EGE
Sbjct: 153 SKGSYSSYQGIIATSLLNLGQIAEETLVEEDLGQAAKPGPGIVHLLQEAAEGAASEEGEK 212
Query: 811 EGEIHAEDGEMKGNEGETESQELSAENHGEAKNDEKGVEDGGGSDGGDSEEEEEEEEEQE 870
I ED E SQ+L ++ +A ++E + G S + EEEEEEEEE+E
Sbjct: 213 GLFIQPEDAEEVVEVTTERSQDLCPQSLEDAASEESSKQKGILSHEEEDEEEEEEEEEEE 272
Query: 871 EEEEEEEQEEEEEEEEEEEEKGNEE 895
E+EEEEE+EEEEEEEEEEEE+ EE
Sbjct: 273 EDEEEEEEEEEEEEEEEEEEEEEEE 297
Score = 45.8 bits (107), Expect = 2e-04
Identities = 48/206 (23%), Positives = 78/206 (37%), Gaps = 26/206 (12%)
Query: 693 EESLNQGARAQP------QAKAESKPEEEEPAKLPAVTVTPAPVPDIKGDQKEN--PGGQ 744
EE L Q A+ P Q AE EE L V ++ ++ ++ P
Sbjct: 181 EEDLGQAAKPGPGIVHLLQEAAEGAASEEGEKGLFIQPEDAEEVVEVTTERSQDLCPQSL 240
Query: 745 EDVAEAESTGEMPGEEGETAGEGETEEKSGGETQPEGEGETETQGKGEECEDENEAEGKG 804
ED A ES+ K G E E E E + + EE EDE E E +
Sbjct: 241 EDAASEESS------------------KQKGILSHEEEDEEEEEEEEEEEEDEEEEEEEE 282
Query: 805 DNEGEDEGEIHAEDGEMKGNEGETESQELSAENHGEAKNDEKGVEDGGGSDGGDSEEEEE 864
+ E E+E E E+ E + E E + ++ + + +K E G E
Sbjct: 283 EEEEEEEEEEEEEEEEEEEEEEEEAAPDVIFQEDTSHTSAQKAPELRGPESPSPKPEYSV 342
Query: 865 EEEEQEEEEEEEEQEEEEEEEEEEEE 890
E + +++++E+ + +E E
Sbjct: 343 IVEVRSDDDKDEDTHSRKSTVTDESE 368
>gi|21735415 centromere protein B [Homo sapiens]
Length = 599
Score = 84.3 bits (207), Expect = 6e-16
Identities = 55/159 (34%), Positives = 85/159 (53%), Gaps = 31/159 (19%)
Query: 751 ESTGEMPGEEGETAGEGETEEKSGGETQPEGEGETETQGKGEECEDENEAEGKGDNEGED 810
+S GE EE E E E EE G E + EGE E E G+GEE +E E E
Sbjct: 402 KSEGE---EEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVE--------- 449
Query: 811 EGEIHAEDGEMKGNEGETESQELSAENHGEAKNDEKGVEDGGGSDGGDSEEEE------- 863
E+G++ +E E E +E S+E EA++ +GV + GGS G +EE
Sbjct: 450 ------EEGDVDSDEEEEEDEESSSEGL-EAEDWAQGVVEAGGSFGAYGAQEEAQCPTLH 502
Query: 864 -----EEEEEQEEEEEEEEQEEEEEEEEEEEEKGNEEPL 897
E+ + EEE++EE+++E+E+++++EE G+E P+
Sbjct: 503 FLEGGEDSDSDSEEEDDEEEDDEDEDDDDDEEDGDEVPV 541
Score = 59.7 bits (143), Expect = 1e-08
Identities = 49/177 (27%), Positives = 80/177 (45%), Gaps = 40/177 (22%)
Query: 707 KAESKPEEEEPAKLPAVTVTPAPVPDIKGDQKENPGGQEDVAEAESTGEMPGEEGETAGE 766
K+E + EEEE + +++E G+E+ E E E GE E E
Sbjct: 402 KSEGEEEEEEEEE----------------EEEEEGEGEEEEEEGEEEEEEGGEGEELGEE 445
Query: 767 GETEEKSGGETQPEGEGETETQGKGEECEDENEAEGKGDNEGEDEGEIHAEDGEMKGNEG 826
E EE+ ++ E E + E+ +G E ED A+G E G+ G
Sbjct: 446 EEVEEEGDVDSDEEEEEDEESSSEGLEAED--WAQGV---------------VEAGGSFG 488
Query: 827 ETESQELSAENHGEAKNDEKGVEDGGGSDGGDSEEEEEEEEEQEEEEEEEEQEEEEE 883
+QE EA+ +GG DSEEE++EEE+ E+E++++++E+ +E
Sbjct: 489 AYGAQE-------EAQCPTLHFLEGGEDSDSDSEEEDDEEEDDEDEDDDDDEEDGDE 538
Score = 55.1 bits (131), Expect = 4e-07
Identities = 35/88 (39%), Positives = 48/88 (54%), Gaps = 7/88 (7%)
Query: 823 GNEGETESQELSAENHGEAKNDEKGVEDGGGSDGGDSEEEEEEEEEQEEEE--EEEEQEE 880
G T + L +E E + +E+ E+ G + + E EEEEEE E EE EEEE EE
Sbjct: 391 GGPNATITTSLKSEGEEEEEEEEEEEEEEGEGEEEEEEGEEEEEEGGEGEELGEEEEVEE 450
Query: 881 E-----EEEEEEEEEKGNEEPLSLDWPE 903
E +EEEEE+EE +E + DW +
Sbjct: 451 EGDVDSDEEEEEDEESSSEGLEAEDWAQ 478
Score = 46.2 bits (108), Expect = 2e-04
Identities = 24/44 (54%), Positives = 27/44 (61%)
Query: 852 GGSDGGDSEEEEEEEEEQEEEEEEEEQEEEEEEEEEEEEKGNEE 895
GG + E E+EEEEEEEE+EEE E EEEEEE EE
Sbjct: 390 GGGPNATITTSLKSEGEEEEEEEEEEEEEEGEGEEEEEEGEEEE 433
Score = 45.1 bits (105), Expect = 4e-04
Identities = 25/47 (53%), Positives = 31/47 (65%), Gaps = 1/47 (2%)
Query: 850 DGGGSDGGDSEEEEEEEEEQEEEEEEEEQEEEEE-EEEEEEEKGNEE 895
+ G G ++ + E EEEEEEEE+EEEEE E EEEEE+G EE
Sbjct: 386 EAGFGGGPNATITTSLKSEGEEEEEEEEEEEEEEGEGEEEEEEGEEE 432
>gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]
Length = 2400
Score = 81.3 bits (199), Expect = 5e-15
Identities = 69/225 (30%), Positives = 106/225 (47%), Gaps = 17/225 (7%)
Query: 680 DPLREVRLAKEKEEESLNQGARAQPQAKAESKPEEEEPAKLPAVTVTPAPVP-DIKGDQK 738
+P E A+E EE + + QP+++ E EE A+ + V V + + +
Sbjct: 1932 EPESEGAEAQEAEEAAQEAEGQTQPESEVIESQEAEEEAQPESEDVEALEVEVETQEAEG 1991
Query: 739 ENPGGQEDVAEAESTGEMPGEEGETAGEGETEEKSGGETQPEGEGE--TETQGKGEECED 796
E EDV E+ GEM E E E + G E QP+ EGE E +G+ ++ E
Sbjct: 1992 EAQPESEDVEAPEAEGEMQEAEEEAQPESD-----GVEAQPKSEGEEAQEVEGETQKTEG 2046
Query: 797 ENEAEGKGDNEGEDEGEIHAEDGEMKGNEGET--ESQELSA-ENHGEAKNDEKGVEDGGG 853
+ + E G E E E +GE++ EGE ES+++ A E GEA+ + +GVE
Sbjct: 2047 DAQPESDGVEAPEAEEEAQEAEGEVQEAEGEAHPESEDVDAQEAEGEAQPESEGVE---- 2102
Query: 854 SDGGDSEEEEEEEEEQEEEEEEEEQEEEEEEEEEEEEKGNEEPLS 898
++E E ++ E E E E E + E E E E +G +P S
Sbjct: 2103 --APEAEGEAQKAEGIEAPETEGEAQPESEGIEAPEAEGEAQPES 2145
Score = 78.6 bits (192), Expect = 3e-14
Identities = 65/223 (29%), Positives = 105/223 (47%), Gaps = 20/223 (8%)
Query: 690 EKEEESLNQGARAQPQAKAESKPEEEEPAKLPAVTVTPAPVPDIKGDQKENPGGQEDVAE 749
E+E + + G AQP+++ E E E + P + D E P +E+ E
Sbjct: 2013 EEEAQPESDGVEAQPKSEGEEAQEVEGETQKTEGDAQP------ESDGVEAPEAEEEAQE 2066
Query: 750 AESTGEMPGEEGETAGEGET--EEKSGGETQPEGEG--ETETQGKGEECEDENEAEGKGD 805
AE GE+ EGE E E +++ GE QPE EG E +G+ ++ E E +G+
Sbjct: 2067 AE--GEVQEAEGEAHPESEDVDAQEAEGEAQPESEGVEAPEAEGEAQKAEGIEAPETEGE 2124
Query: 806 NEGEDEGEIHAEDGEMKGNEGETESQELSAEN-HGEAKNDEKGVEDGGGSDGGDSEEEEE 864
+ E EG I A + E E + ES+ + A++ GEA+ + +G+E + + + E
Sbjct: 2125 AQPESEG-IEAPEAE---GEAQPESEGVEAQDAEGEAQPESEGIE---AQEAEEEAQPEL 2177
Query: 865 EEEEQEEEEEEEEQEEEEEEEEEEEEKGNEEPLSLDWPETRQK 907
E E E E E + E E E E E + E ++ PE ++
Sbjct: 2178 EGVEAPEAEGEAQPESEGIEAPEAEGEAQPELEGVEAPEAEEE 2220
Score = 76.6 bits (187), Expect = 1e-13
Identities = 75/230 (32%), Positives = 101/230 (43%), Gaps = 39/230 (16%)
Query: 681 PLREVRLAKEKEEESLNQGARAQPQAKAESKPEEEEPAKLPAVTVTPAPVPDIKGDQKEN 740
P E A+E E E+ AQP++ PE EE A+ + +G+ +E
Sbjct: 2027 PKSEGEEAQEVEGETQKTEGDAQPESDGVEAPEAEEEAQ------------EAEGEVQEA 2074
Query: 741 PGG----QEDVAEAESTGE-MPGEEGETAGEGETE-EKSGGETQPEGEGETETQGKG--- 791
G EDV E+ GE P EG A E E E +K+ G PE EGE + + +G
Sbjct: 2075 EGEAHPESEDVDAQEAEGEAQPESEGVEAPEAEGEAQKAEGIEAPETEGEAQPESEGIEA 2134
Query: 792 EECEDENEAEGKGDNEGEDEGEIHAEDGEMKGNEGETESQ-ELSA----ENHGEAKNDEK 846
E E E + E +G + EGE E ++ E E E+Q EL E GEA+ + +
Sbjct: 2135 PEAEGEAQPESEGVEAQDAEGEAQPESEGIEAQEAEEEAQPELEGVEAPEAEGEAQPESE 2194
Query: 847 GVEDGGGSDGGDSEEEEEEEEEQEEEEEEEEQEEEEEEEEEEEEKGNEEP 896
G+E E E E Q E E E E EEE + E E G E P
Sbjct: 2195 GIE-----------APEAEGEAQPELEGVEAPEAEEEAQPEPE--GVETP 2231
Score = 73.6 bits (179), Expect = 1e-12
Identities = 63/229 (27%), Positives = 108/229 (47%), Gaps = 27/229 (11%)
Query: 690 EKEEESLNQGARAQPQAKAESKPEEEEPAKLPAVTVTPAPVPDIKGDQKENPGGQEDVAE 749
E E + ++GA A P+A+ E++PE E + A+ P+ +G + + AE
Sbjct: 1896 EWEVQPESEGAEA-PEAEKEAQPETES---VEALETEGEDEPESEGAEAQEAEEAAQEAE 1951
Query: 750 AESTGE---MPGEEGETAGEGETEE-----------KSGGETQPEGEGETETQGKGEECE 795
++ E + +E E + E+E+ ++ GE QPE E + +GE E
Sbjct: 1952 GQTQPESEVIESQEAEEEAQPESEDVEALEVEVETQEAEGEAQPESEDVEAPEAEGEMQE 2011
Query: 796 DENEAEGKGD-------NEGEDEGEIHAEDGEMKGNEGETESQELSA-ENHGEAKNDEKG 847
E EA+ + D +EGE+ E+ E + +G + + ES + A E EA+ E
Sbjct: 2012 AEEEAQPESDGVEAQPKSEGEEAQEVEGETQKTEG-DAQPESDGVEAPEAEEEAQEAEGE 2070
Query: 848 VEDGGGSDGGDSEEEEEEEEEQEEEEEEEEQEEEEEEEEEEEEKGNEEP 896
V++ G +SE+ + +E E E + E E E E E E ++ +G E P
Sbjct: 2071 VQEAEGEAHPESEDVDAQEAEGEAQPESEGVEAPEAEGEAQKAEGIEAP 2119
Score = 70.5 bits (171), Expect = 8e-12
Identities = 60/208 (28%), Positives = 88/208 (42%), Gaps = 42/208 (20%)
Query: 734 KGDQKENPGGQEDVAEAESTGEMPGEEGETAGEGETEE---------------------- 771
K E G E + EAE GE E GET G+G E
Sbjct: 1775 KTHNSETSAGSE-LGEAEQEGEGISERGETGGQGSGHEDNLQGEAAAGGDQDPGQSDGAE 1833
Query: 772 -----KSGGETQPEGEG--ETETQGKGEECEDENEAEGKGDNEGEDEGEIHAEDGEMKGN 824
++ GE QPE EG E +G +E E E + E + E EGE E +++
Sbjct: 1834 GIEAPEAEGEAQPESEGVEAPEAEGDAQEAEGEAQPESEDVEAPEAEGEAQPESEDVETP 1893
Query: 825 EGETESQELS-----AENHGEAKNDEKGV-------EDGGGSDGGDSEEEEEEEEEQEEE 872
E E E Q S E EA+ + + V ED S+G +++E EE +E E +
Sbjct: 1894 EAEWEVQPESEGAEAPEAEKEAQPETESVEALETEGEDEPESEGAEAQEAEEAAQEAEGQ 1953
Query: 873 EEEEEQEEEEEEEEEEEEKGNEEPLSLD 900
+ E + E +E EEE + +E+ +L+
Sbjct: 1954 TQPESEVIESQEAEEEAQPESEDVEALE 1981
Score = 70.5 bits (171), Expect = 8e-12
Identities = 68/241 (28%), Positives = 104/241 (43%), Gaps = 52/241 (21%)
Query: 704 PQAKAESKPEEEEPAKLPAVTVTPAPVPDIKGDQKENPGG----QEDVAEAESTGEMPGE 759
P+A+ E++PE E P+ +GD +E G EDV E+ GE E
Sbjct: 1838 PEAEGEAQPESEG-----------VEAPEAEGDAQEAEGEAQPESEDVEAPEAEGEAQPE 1886
Query: 760 EGETA---GEGETEEKSGGETQPEGEGETETQGKGEEC-----EDENEAEGKGDNEGED- 810
+ E E + +S G PE E E + + + E EDE E+EG E E+
Sbjct: 1887 SEDVETPEAEWEVQPESEGAEAPEAEKEAQPETESVEALETEGEDEPESEGAEAQEAEEA 1946
Query: 811 ----EGEIHAEDGEMKGNEGETESQELSA------------ENHGEAKNDEKGVEDGGGS 854
EG+ E ++ E E E+Q S E GEA+ + + VE +
Sbjct: 1947 AQEAEGQTQPESEVIESQEAEEEAQPESEDVEALEVEVETQEAEGEAQPESEDVE----A 2002
Query: 855 DGGDSEEEEEEEEEQEEEEEEEEQEEEEEEEEEEEE------KGNEEPLS--LDWPETRQ 906
+ E +E EEE Q E + E Q + E EE +E E +G+ +P S ++ PE +
Sbjct: 2003 PEAEGEMQEAEEEAQPESDGVEAQPKSEGEEAQEVEGETQKTEGDAQPESDGVEAPEAEE 2062
Query: 907 K 907
+
Sbjct: 2063 E 2063
Score = 68.9 bits (167), Expect = 2e-11
Identities = 73/264 (27%), Positives = 110/264 (41%), Gaps = 45/264 (17%)
Query: 688 AKEKEEESLNQGARAQPQAKAESKPEEEEPAKLPAVTV-TPAPVPDIKGDQKENPGGQED 746
A E E ++ AQP+++ PE E A+ + V TP ++ Q E+ G +
Sbjct: 1853 APEAEGDAQEAEGEAQPESEDVEAPEAEGEAQPESEDVETPEAEWEV---QPESEGAEAP 1909
Query: 747 VAEAESTGEMPGEEG-ETAGEGETE-------------EKSGGETQPEGE------GETE 786
AE E+ E E ET GE E E +++ G+TQPE E E E
Sbjct: 1910 EAEKEAQPETESVEALETEGEDEPESEGAEAQEAEEAAQEAEGQTQPESEVIESQEAEEE 1969
Query: 787 TQGKGEECE------DENEAEGKGDNEGED------EGEIHAEDGEMKGNEGETESQELS 834
Q + E+ E + EAEG+ E ED EGE+ + E + E+Q S
Sbjct: 1970 AQPESEDVEALEVEVETQEAEGEAQPESEDVEAPEAEGEMQEAEEEAQPESDGVEAQPKS 2029
Query: 835 AENHGEAKNDEKGVEDGGG---SDGGDSEEEEEEEEEQEEEEEEEE------QEEEEEEE 885
+ E +G SDG ++ E EEE +E E E +E E E+ + +E
Sbjct: 2030 EGEEAQEVEGETQKTEGDAQPESDGVEAPEAEEEAQEAEGEVQEAEGEAHPESEDVDAQE 2089
Query: 886 EEEEEKGNEEPLSLDWPETRQKQA 909
E E + E + E ++A
Sbjct: 2090 AEGEAQPESEGVEAPEAEGEAQKA 2113
Score = 61.6 bits (148), Expect = 4e-09
Identities = 54/190 (28%), Positives = 78/190 (41%), Gaps = 23/190 (12%)
Query: 688 AKEKEEESLNQGARAQPQAKAESKPEEEEPAKLPAVTVTPAPVPDIKGD-QKENPGGQED 746
A E E E+ P+ + E++PE E P+ +G+ Q E+ G +
Sbjct: 2103 APEAEGEAQKAEGIEAPETEGEAQPESEG-----------IEAPEAEGEAQPESEGVEAQ 2151
Query: 747 VAEAESTGEMPGEEGETAGEGETEEKSGGETQPEGEGETETQGKGEEC-----EDENEAE 801
AE E+ E G E + A E E G E PE EGE + + +G E E + E E
Sbjct: 2152 DAEGEAQPESEGIEAQEAEEEAQPELEGVEA-PEAEGEAQPESEGIEAPEAEGEAQPELE 2210
Query: 802 GKGDNEGEDEGEIHAEDGEMKGNEGETESQELSAENHGEAKNDEKGVEDGGGSDGGDSEE 861
G E E+E + E E EGE + E+ GE + ++KG DG E
Sbjct: 2211 GVEAPEAEEEAQPEPEGVETPEAEGEAQ-----PESEGETQGEKKGSPQVSLGDGQSEEA 2265
Query: 862 EEEEEEEQEE 871
E E+
Sbjct: 2266 SESSSPVPED 2275
Score = 61.2 bits (147), Expect = 5e-09
Identities = 51/169 (30%), Positives = 71/169 (42%), Gaps = 22/169 (13%)
Query: 732 DIKGDQKENPGGQEDVAEAESTGEMPGEEGETAGEGETEEKSGGETQPEGEG-----ETE 786
D +G Q+ N + EAE EG+T + GE + EGEG ET
Sbjct: 1745 DGEGSQRLNRDKDPKLGEAEGDAMAQEREGKTHNSETSAGSELGEAEQEGEGISERGETG 1804
Query: 787 TQGKGEECEDENEAEGKGDNEGEDEGEIHAEDGEMKGNEGETESQELSAENHGEAKNDEK 846
QG G E + EA GD + G+ G EG + E GEA+ + +
Sbjct: 1805 GQGSGHEDNLQGEAAAGGDQD----------PGQSDGAEGIE-----APEAEGEAQPESE 1849
Query: 847 GVEDGGGSDGGDSEEEEEEEEEQEEEEEEEEQEEEEEEEEEEEEKGNEE 895
GVE GD++E E E + + E+ E E E E + E E+ E E
Sbjct: 1850 GVE--APEAEGDAQEAEGEAQPESEDVEAPEAEGEAQPESEDVETPEAE 1896
Score = 57.4 bits (137), Expect = 7e-08
Identities = 44/149 (29%), Positives = 67/149 (44%), Gaps = 10/149 (6%)
Query: 757 PG-EEGETAGEGETEEKSGGETQPE-GEGETETQGKGEECEDENEAEGKGDNEGEDEGEI 814
PG +EGE +GE ++ + P+ GE E + + E + N G GE E
Sbjct: 1738 PGVDEGE---DGEGSQRLNRDKDPKLGEAEGDAMAQEREGKTHNSETSAGSELGEAE--- 1791
Query: 815 HAEDGEMKGNEGETESQELSAENHGEAKNDEKGVEDGGGSDGGDSEEEEEEEEEQEEEEE 874
++GE GET Q E++ + + G +D G SDG + E E E E + E E
Sbjct: 1792 --QEGEGISERGETGGQGSGHEDNLQGEAAAGGDQDPGQSDGAEGIEAPEAEGEAQPESE 1849
Query: 875 EEEQEEEEEEEEEEEEKGNEEPLSLDWPE 903
E E E + +E E + E ++ PE
Sbjct: 1850 GVEAPEAEGDAQEAEGEAQPESEDVEAPE 1878
Score = 48.9 bits (115), Expect = 3e-05
Identities = 62/225 (27%), Positives = 90/225 (40%), Gaps = 37/225 (16%)
Query: 690 EKEEESLNQGARAQPQAKAESKPEEEEPAKLPAVTVTPAPVPDIKGDQKENPGGQEDVAE 749
E E +S Q A + + AE+ +EE + + K + E G QE+ +
Sbjct: 1275 EAERDSEEQRASSNLEQLAENTVQEE------------VQLEETK-EGTEGEGLQEEAVQ 1321
Query: 750 AESTGEMPG--EEG-------ETAGEGETEEKSGGETQPEGEGETETQGKGEECEDENEA 800
E T G EEG ET GEG+ EE++ + E ET G+G + E
Sbjct: 1322 LEETKTEEGLQEEGVQLEETKETEGEGQQEEEA------QLEEIEETGGEGLQEEGVQLE 1375
Query: 801 EGKGDNEGEDEGEIHAEDGEMKG--NEGETESQELSAENHGEAK---NDEKGVEDGGGSD 855
E K EG +GE E + +G EG QELS + + K D+ E+ G
Sbjct: 1376 EVKEGPEGGLQGEALEEGLKEEGLPEEGSVHGQELSEASSPDGKGSQEDDPVQEEEAGRA 1435
Query: 856 GGDSE----EEEEEEEEQEEEEEEEEQEEEEEEEEEEEEKGNEEP 896
+E E EE E E + E + + E G E+P
Sbjct: 1436 SASAEPCPAEGTEEPTEPPSHLSETDPSASERQSGSQLEPGLEKP 1480
Score = 39.3 bits (90), Expect = 0.021
Identities = 46/154 (29%), Positives = 66/154 (42%), Gaps = 21/154 (13%)
Query: 745 EDVAEAESTGEMPGEEGETAGEGETEEKSGGETQPEGEGETETQGKGEECEDENEAEGKG 804
ED AE +S + E E +E+ E EG T+G+G + E+ + E
Sbjct: 1273 EDEAERDSEEQRASSNLEQLAENTVQEEVQLEETKEG-----TEGEGLQ-EEAVQLEETK 1326
Query: 805 DNEGEDEGEIHAEDGEMKGNEGETESQELSAENHGEAKNDEKGVEDGGG----SDGGDSE 860
EG E + E E K EGE + +E EA+ +E +E+ GG +G E
Sbjct: 1327 TEEGLQEEGVQLE--ETKETEGEGQQEE-------EAQLEE--IEETGGEGLQEEGVQLE 1375
Query: 861 EEEEEEEEQEEEEEEEEQEEEEEEEEEEEEKGNE 894
E +E E + E EE +EE EE G E
Sbjct: 1376 EVKEGPEGGLQGEALEEGLKEEGLPEEGSVHGQE 1409
Score = 37.7 bits (86), Expect = 0.060
Identities = 26/104 (25%), Positives = 49/104 (47%), Gaps = 2/104 (1%)
Query: 809 EDEGEIHAEDGEMKGNEGETESQELSAENHGEAKNDEKGVEDGGGSDGGDSEEEEEEEEE 868
EDE E +E E + + + E + + + + ++G E G + EE + EE
Sbjct: 1273 EDEAERDSE--EQRASSNLEQLAENTVQEEVQLEETKEGTEGEGLQEEAVQLEETKTEEG 1330
Query: 869 QEEEEEEEEQEEEEEEEEEEEEKGNEEPLSLDWPETRQKQAIYL 912
+EE + E+ +E E E ++EE+ E + E Q++ + L
Sbjct: 1331 LQEEGVQLEETKETEGEGQQEEEAQLEEIEETGGEGLQEEGVQL 1374
Score = 36.2 bits (82), Expect = 0.18
Identities = 33/114 (28%), Positives = 54/114 (47%), Gaps = 6/114 (5%)
Query: 784 ETETQGKGEECEDENEAEGKGDNEGEDEGEIHAEDGEMKGNEGETESQELSAENHGEAKN 843
E E + EE + E +N ++E ++ + +G EGE +E A E K
Sbjct: 1273 EDEAERDSEEQRASSNLEQLAENTVQEEVQL---EETKEGTEGEGLQEE--AVQLEETKT 1327
Query: 844 DEKGVEDGGG-SDGGDSEEEEEEEEEQEEEEEEEEQEEEEEEEEEEEEKGNEEP 896
+E E+G + ++E E ++EEE + EE EE E +EE + E+ E P
Sbjct: 1328 EEGLQEEGVQLEETKETEGEGQQEEEAQLEEIEETGGEGLQEEGVQLEEVKEGP 1381
Score = 34.3 bits (77), Expect = 0.67
Identities = 33/128 (25%), Positives = 51/128 (39%), Gaps = 15/128 (11%)
Query: 689 KEKEEESLNQGARAQPQAKAESKPEEEEPAKLPAVTVTPAPVPDIKGDQKENPGGQEDVA 748
KE E L QG + K E PEE + ++ A PD KG Q+++P +E+
Sbjct: 1378 KEGPEGGL-QGEALEEGLKEEGLPEE---GSVHGQELSEASSPDGKGSQEDDPVQEEEAG 1433
Query: 749 EAESTGE-MPGEEGETAGE----------GETEEKSGGETQPEGEGETETQGKGEECEDE 797
A ++ E P E E E +E +SG + +P E G+E
Sbjct: 1434 RASASAEPCPAEGTEEPTEPPSHLSETDPSASERQSGSQLEPGLEKPPGATMMGQEHTQA 1493
Query: 798 NEAEGKGD 805
+G +
Sbjct: 1494 QPTQGAAE 1501
Score = 33.5 bits (75), Expect = 1.1
Identities = 44/207 (21%), Positives = 76/207 (36%), Gaps = 27/207 (13%)
Query: 690 EKEEESLNQGARAQPQAKAESKPE---------EEEPAKLPAVTVTPAPVPDIKGDQKEN 740
E E + ++G A P+A+ E++PE EEE P TP + + + +
Sbjct: 2186 EGEAQPESEGIEA-PEAEGEAQPELEGVEAPEAEEEAQPEPEGVETPEAEGEAQPESEGE 2244
Query: 741 PGGQEDVAEAESTGEMPGEEGETAGEGETEEKSGGETQPEGEGETETQGKGEECEDENEA 800
G++ + S G+ EE + E++ P G+T Q G +
Sbjct: 2245 TQGEKKGSPQVSLGDGQSEEASESSSPVPEDRP--TPPPSPGGDTPHQRPGSQ------- 2295
Query: 801 EGKGDNEGEDEGEIHAEDGEMKGNEGETESQELSAEN--HGEAKNDEKGVEDGGGSDGGD 858
G + G +D E G+T S + + H E K E
Sbjct: 2296 TGPSSSRASSWGNCWQKDSENDHVLGDTRSPDAKSTGTPHAERKATRMYPE------SST 2349
Query: 859 SEEEEEEEEEQEEEEEEEEQEEEEEEE 885
SE+EE + E+ E + +E++
Sbjct: 2350 SEQEEAPLGSRTPEQGASEGYDLQEDQ 2376
Score = 30.4 bits (67), Expect = 9.6
Identities = 31/131 (23%), Positives = 46/131 (35%), Gaps = 11/131 (8%)
Query: 744 QEDVAEAESTGEMPGEEGETAGEGETEEKSGGETQPEGEGETETQGKGEECEDENEA-EG 802
Q+ + A STG G E E++ T E P + E + G ED +G
Sbjct: 450 QDSASPASSTGLPEGSEPESSCCPRTPEDGVDSASPSAQIGAERKAGGSLGEDPGLCIDG 509
Query: 803 KGDNEGEDEGEIHAEDGEMKGNEGETESQELSAENHGEAKNDEKGVEDGGGSDGGDSEEE 862
G E G + + EG + S +H +G + GG G +
Sbjct: 510 AGLGGPEQGGRL---TPRARSEEGASSDSSASTGSH-------EGSSEWGGRPQGCPGKA 559
Query: 863 EEEEEEQEEEE 873
E +QE E
Sbjct: 560 RAETSQQEASE 570
>gi|169218106 PREDICTED: hypothetical protein, partial [Homo
sapiens]
Length = 436
Score = 79.7 bits (195), Expect = 1e-14
Identities = 63/241 (26%), Positives = 114/241 (47%), Gaps = 21/241 (8%)
Query: 688 AKEKEEESLNQGARAQPQAKAESKPEEEEPAKLPA-----VTVTPAPVPDIKGDQKENPG 742
A+ +EE L + +++ Q + + E K+P V V + +G +E G
Sbjct: 14 AELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQVREQEGQVREQEG 73
Query: 743 G--QEDVAEAESTGEMPGEEGETAG-EGETEEKSGGETQPEG-----EGETETQGKGEEC 794
+++ E G++ +EG+ EG+ E+ G + EG EG+ Q +G+
Sbjct: 74 QVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ-EGQVR 132
Query: 795 EDENEAEGKGDNEGEDEGEIHAEDGEMKGNEGETESQELSA-ENHGEAKNDEKGVEDGGG 853
E E + + E EG++ ++G+++ EG+ QE E G+ + E V + G
Sbjct: 133 EQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEG 192
Query: 854 SDG------GDSEEEEEEEEEQEEEEEEEEQEEEEEEEEEEEEKGNEEPLSLDWPETRQK 907
G G+ EE+ E+EEQ +++EE+ E+EE+ ++EE+ G +E E QK
Sbjct: 193 QMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQK 252
Query: 908 Q 908
Q
Sbjct: 253 Q 253
Score = 63.2 bits (152), Expect = 1e-09
Identities = 49/216 (22%), Positives = 100/216 (46%), Gaps = 12/216 (5%)
Query: 689 KEKEEESLNQGARAQPQAKAESKPEEEEPAKLPAVTVTPAPVPDIKGDQKENPGG--QED 746
+E+E + Q + + Q + E + + V V + +G +E G +++
Sbjct: 118 REQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQE 177
Query: 747 VAEAESTGEMPGEEGETAGEGETEEKSGGETQPEGEGETETQGKGEECEDENEAEGKGDN 806
E G++ +EG+ GE E + G + + GE E + Q + E+ ++ E K +
Sbjct: 178 GQVREQEGQVREQEGQM---GEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEE 234
Query: 807 E-GEDEGEIHAEDGEMKGNEGETESQELSAENHGEAKNDE-----KGVEDGGGSDGGDSE 860
+ GE E ++ ++ +++ E + QE E ++ K E + +
Sbjct: 235 QMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQ 294
Query: 861 EEEEEEEEQEEEEEEEEQEEEEEE-EEEEEEKGNEE 895
EE+ E+E++ E+EE+ E+EE+ E+EE+ G +E
Sbjct: 295 EEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQE 330
Score = 62.8 bits (151), Expect = 2e-09
Identities = 53/227 (23%), Positives = 108/227 (47%), Gaps = 9/227 (3%)
Query: 689 KEKEEESLNQGARAQPQAKAESKPEEEEPAKLPAVTVTPAPVPDIKGDQKENPGG--QED 746
+E+E + Q + + Q + E + + V V + +G +E G +++
Sbjct: 97 REQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQE 156
Query: 747 VAEAESTGEMPGEEGETAG-EGETEEKSGGETQPEGE-GETETQ-GKGEEC--EDENEAE 801
E G++ +EG+ EG+ E+ G + EG+ GE E Q G+ EE E E + +
Sbjct: 157 GQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQ 216
Query: 802 GKGDNEGEDEGEIHAEDGEMKGNEGETESQELSAENHGEAKNDEKGVEDGGGSDGGDSEE 861
+ + GE E ++ ++ +M E + + QE + E ++ E + E+
Sbjct: 217 KQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQE--EQMREQEEQMREQ 274
Query: 862 EEEEEEEQEEEEEEEEQEEEEEEEEEEEEKGNEEPLSLDWPETRQKQ 908
EE+ +++E+ E+EE+ E+EE+ E+EE+ E+ + E + ++
Sbjct: 275 EEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMRE 321
Score = 60.5 bits (145), Expect = 9e-09
Identities = 54/227 (23%), Positives = 102/227 (44%), Gaps = 14/227 (6%)
Query: 689 KEKEEESLNQGARAQPQAKAESKPEEEEPAKLPAVTVTPAPVPDIKGDQKENPGGQEDVA 748
+E+E + Q + + Q + E + + V V + +G +E G V
Sbjct: 125 REQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEG---QVR 181
Query: 749 EAES-TGEMPGEEGETAGEGETEEKSGGETQPEGEGETETQGKGEECEDENEAEGKGDNE 807
E E E G+ GE G+ +E+ GE + + + + E G+ EE + + E G+ E
Sbjct: 182 EQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEE-QMRKQEEQMGEQE 240
Query: 808 GE---DEGEIHAEDGEMKGNEGETESQELSAENHGEA---KNDEKGVEDGGGSDGGDSEE 861
+ E ++ ++ +M+ E + QE E + ++ E+ G E
Sbjct: 241 EQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMRE 300
Query: 862 EEEEEEEQEEE--EEEEEQEEEEEEEEEEEEKGNEEPLSLDWPETRQ 906
+EE+ EQEE+ E+EE+ E+EE+ ++EE+ E+ + W + Q
Sbjct: 301 QEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQM-WEQKEQ 346
Score = 60.1 bits (144), Expect = 1e-08
Identities = 52/235 (22%), Positives = 107/235 (45%), Gaps = 17/235 (7%)
Query: 689 KEKEEESLNQGARAQPQAKAESKPEEEEPAKLPAVTVTPAPVPDIKGDQKENPGG--QED 746
+E+E + Q + + Q + E + + V V + +G +E G +++
Sbjct: 132 REQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQE 191
Query: 747 VAEAESTGEMPGEEGETAGE------------GETEEKSGGETQPEGEGETETQGKGEEC 794
E G+M GE+ E GE GE EE+ + + GE E + Q + E+
Sbjct: 192 GQMGEQEGQM-GEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQV 250
Query: 795 EDENEAEGKGDNE-GEDEGEIHAEDGEMKGNEGETESQELSAENHGEAKNDEKGVEDGGG 853
+ + E K + + E E ++ ++ +M + +TE +E + E + + E+ + +
Sbjct: 251 QKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEE 310
Query: 854 SDGGDSEEEEEEEEEQEEEEEEEEQEEEEEEEEEEEEKGNEEPLSLDWPETRQKQ 908
E+ E+EE+ ++EE+ +++E+ E++E+ EE + + E QKQ
Sbjct: 311 QMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMG-EQEEQMQKQ 364
Score = 53.9 bits (128), Expect = 8e-07
Identities = 43/207 (20%), Positives = 94/207 (45%), Gaps = 23/207 (11%)
Query: 690 EKEEESLNQGARAQPQAKAESKPEEEEPAKLPAVTVTPAPVPDIKGDQKENPGGQEDVAE 749
+K+EE + + + + + + +EE+ K T +Q+E G QE+
Sbjct: 251 QKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQT-----------EQEEQTGEQEEQMR 299
Query: 750 AESTGEMPGEEGETAGEGETEEKSGGETQPEGEGETETQGKGEECEDENEAEGKGDNE-G 808
E +M +E + E EE+ + + G+ E + + E+ ++ E K + + G
Sbjct: 300 -EQEEQMREQEEQMR---EQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMG 355
Query: 809 EDEGEIHAEDGEMKGNEGETESQELSAENHGEAKNDEKGVEDGGGSDGGDSEEEEEEEEE 868
E E ++ ++ +++ E + QE E ++ G+ +E+ E++E
Sbjct: 356 EQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQE-------EQMGEQKEQMGEQKE 408
Query: 869 QEEEEEEEEQEEEEEEEEEEEEKGNEE 895
Q E+EE+ E++E+ ++EE G ++
Sbjct: 409 QMREQEEQMGEQKEQMRKQEEHMGEQK 435
Score = 48.1 bits (113), Expect = 4e-05
Identities = 51/226 (22%), Positives = 98/226 (43%), Gaps = 22/226 (9%)
Query: 690 EKEEESLNQGARAQPQAKAESKPEEEEPAKLPAVTVTPAPVPDIKGDQKENPGGQEDVAE 749
E+EE+ Q + Q Q + + EE+ + + G+Q+E QE+ +
Sbjct: 203 EQEEQMGEQEEQMQKQEEQMGEQEEQMRKQ-----------EEQMGEQEEQVQKQEEQVQ 251
Query: 750 AESTGEMPGEEGETAGEGETEEKSGGETQPEGEGETETQGKGEECEDENEAEGKGDNEGE 809
+ EE E + E+ + + + E E Q GE+ E E E + E
Sbjct: 252 KQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQ-TGEQEEQMREQE---EQMRE 307
Query: 810 DEGEIHAEDGEMKGNEGETESQELSAENHGEAKNDEKGVEDGGGSDGGDSEEEEEEEEEQ 869
E ++ ++ +M+ E + QE E ++K G+ EE+ +++EEQ
Sbjct: 308 QEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQ 367
Query: 870 EEEEEE-----EEQEEEEEEE--EEEEEKGNEEPLSLDWPETRQKQ 908
++EE EEQ ++EE+ ++EE+ G ++ + E ++Q
Sbjct: 368 VRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQ 413
Score = 46.6 bits (109), Expect = 1e-04
Identities = 41/220 (18%), Positives = 95/220 (43%), Gaps = 8/220 (3%)
Query: 690 EKEEESLNQGARAQPQAKAESKPEEEEPAKLPAVTVTPAPVPDIKGDQKENPGGQEDVAE 749
+K+EE + G + + K E + E+E ++ +++ +E + E
Sbjct: 216 QKQEEQM--GEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMRE 273
Query: 750 AESTGEMPGEEGETAGE-GETEEKSGGETQPEGEGETETQGKGEECEDENEAEGKGDNEG 808
E E+ E + GE EE+ + + E E + + + E+ ++ E GK + +
Sbjct: 274 QEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQM 333
Query: 809 EDEGEIHAEDGEMKGNEGETESQELSAENHGEAKNDEKGVEDGGGSDGGDSEEEEEEEEE 868
++ E E E + +E E + + E+ V E+ ++EE+
Sbjct: 334 WEQKEQMWEQKEQMWKQ-----EEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQ 388
Query: 869 QEEEEEEEEQEEEEEEEEEEEEKGNEEPLSLDWPETRQKQ 908
++EE+ +++E+ E++E+ + EE + + R+++
Sbjct: 389 MRKQEEQMGEQKEQMGEQKEQMREQEEQMGEQKEQMRKQE 428
>gi|55956788 nucleolin [Homo sapiens]
Length = 710
Score = 79.3 bits (194), Expect = 2e-14
Identities = 62/221 (28%), Positives = 100/221 (45%), Gaps = 14/221 (6%)
Query: 700 ARAQPQAKAESKPEEEEPAKLPAVTVTPAPVPDIKGDQKENPGGQEDVAEAESTGEMPGE 759
A A P KA P ++ A TVTPA G + PG + +P +
Sbjct: 73 AVATPAKKAAVTPGKKAAATPAKKTVTPAKAVTTPGKKGATPGKALVATPGKKGAAIPAK 132
Query: 760 EGETAGEGETEEKSGGETQPEGEGETETQGKGEECEDENEAE------GKGDNEGEDEGE 813
A G+ +K + + + + E + + +E EDE+E E EDE +
Sbjct: 133 G---AKNGKNAKKEDSDEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAAPASEDEDD 189
Query: 814 IHAEDGEMKGNEGETESQELSAENH-GEAKNDEKGVEDGGGSDGGDSEEEEEEEEEQEEE 872
ED E ++ E +S+E + E + K K V + D +EEE++E+E +++
Sbjct: 190 EDDEDDEDDDDDEEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEEDDEDEDDDD 249
Query: 873 EEEEE----QEEEEEEEEEEEEKGNEEPLSLDWPETRQKQA 909
+E++E +++EEEEEEEEEE E P +QK A
Sbjct: 250 DEDDEDDDDEDDEEEEEEEEEEPVKEAPGKRKKEMAKQKAA 290
Score = 38.1 bits (87), Expect = 0.046
Identities = 34/161 (21%), Positives = 71/161 (44%), Gaps = 10/161 (6%)
Query: 689 KEKEEESLNQGARAQPQAKAESKPEEE-EPAKLPAVTVTPAPVPDIKGDQKENPGG---Q 744
++ +EE + + + E + E+E EPA + A PA + D +++ +
Sbjct: 143 EDSDEEEDDDSEEDEEDDEDEDEDEDEIEPAAMKAAAAAPASEDEDDEDDEDDEDDDDDE 202
Query: 745 EDVAEAESTGEMPGEEGETAGEGETEEKSGGETQPEGEGETETQGKGEECEDENEAEGKG 804
ED +E E+ P + + A + K+ E + E E + + +E +DE++ +
Sbjct: 203 EDDSEEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEEDDEDEDDDDDE-DDEDDDDEDD 261
Query: 805 DNEGEDEGEIHAEDGEMKGNEGETESQELSAENHGEAKNDE 845
+ E E+E E+ +K G+ + + + EAK +
Sbjct: 262 EEEEEEE-----EEEPVKEAPGKRKKEMAKQKAAPEAKKQK 297
Score = 33.1 bits (74), Expect = 1.5
Identities = 14/38 (36%), Positives = 23/38 (60%)
Query: 853 GSDGGDSEEEEEEEEEQEEEEEEEEQEEEEEEEEEEEE 890
G + GD ++ +E EE+ E+EE E+EE++ EE
Sbjct: 8 GKNQGDPKKMAPPPKEVEEDSEDEEMSEDEEDDSSGEE 45
>gi|39995086 solute carrier family 24 member 6 [Homo sapiens]
Length = 584
Score = 78.2 bits (191), Expect = 4e-14
Identities = 51/181 (28%), Positives = 86/181 (47%), Gaps = 20/181 (11%)
Query: 432 PDLHPKGEY-----------PPDLFSVEERRQGWVVLHVFGMMYVFVALAIVCDEYFVPA 480
PD H G Y PP L + V L+V ++Y+F+ L + ++F P
Sbjct: 72 PDCHSDGGYLDYLEGIFCHFPPSLLPLA------VTLYVSWLLYLFLILGVTAAKFFCPN 125
Query: 481 LGVITDKLQISEDVAGATFMAAGGSAPELFTSLIGVFISH-SNVGIGTIVGSAVFNILFV 539
L I+ L++S +VAG TF+A G AP++F++L+ H + + +G + G+ V V
Sbjct: 126 LSAISTTLKLSHNVAGVTFLAFGNGAPDIFSALVAFSDPHTAGLALGALFGAGVLVTTVV 185
Query: 540 IGTCSLFSREILNLTWWPLFRDVSFYILDLIMLILFFLDSLIAWWESLLLLLAYAFYVFT 599
G ++ + P FRD+ FY++ + + L + +L L Y FYV T
Sbjct: 186 AGGITILHPFMAASR--PFFRDIVFYMVAVFLTFLMLFRGRVTLAWALGYLGLYVFYVVT 243
Query: 600 M 600
+
Sbjct: 244 V 244
Score = 73.2 bits (178), Expect = 1e-12
Identities = 51/168 (30%), Positives = 89/168 (52%), Gaps = 6/168 (3%)
Query: 931 QESRKFFVFTFLG---SIMWIAMFSYLMVWWAHQVGETIGISEEIMGLTILAAGTSIPDL 987
Q R ++F FLG S +WI + +V +G +S ++GLT+LA G SI D
Sbjct: 413 QPPRLHWLFAFLGFLTSALWINAAATEVVNILRSLGVVFRLSNTVLGLTLLAWGNSIGDA 472
Query: 988 ITSVIVARKGLGDMAVSSSVGSNIFDITVGLPVPWLLFSLINGLQPVPVSSNGLFCAIV- 1046
+ +AR+G MA S+ G IF+I VG+ + LL + V + +GL ++
Sbjct: 473 FSDFTLARQGYPRMAFSACFGGIIFNILVGVGLGCLL-QISRSHTEVKLEPDGLLVWVLA 531
Query: 1047 -LLFLMLLFVISSIASCKWRMNKILGFTMFLLYFVFLIISVMLEDRII 1093
L L L+F + S+ ++++++ GF + L Y FL+++++ E +I
Sbjct: 532 GALGLSLVFSLVSVPLQCFQLSRVYGFCLLLFYLNFLVVALLTEFGVI 579
Score = 34.3 bits (77), Expect = 0.67
Identities = 29/132 (21%), Positives = 57/132 (43%), Gaps = 19/132 (14%)
Query: 962 VGETIGISEEIMGLTILAAGTSIPDLITSVIV-ARKGLGDMAVSSSVGSNIFDITVGLPV 1020
+ T+ +S + G+T LA G PD+ ++++ + +A+ + G+ + TV
Sbjct: 129 ISTTLKLSHNVAGVTFLAFGNGAPDIFSALVAFSDPHTAGLALGALFGAGVLVTTV---- 184
Query: 1021 PWLLFSLINGLQPVPVSSNGLFCAIVL----LFLMLLFVISSIASCKWRMNKILGFTMFL 1076
+ I L P +S F IV +FL L + + W + +L
Sbjct: 185 ---VAGGITILHPFMAASRPFFRDIVFYMVAVFLTFLMLFRGRVTLAWALG-------YL 234
Query: 1077 LYFVFLIISVML 1088
+VF +++V+L
Sbjct: 235 GLYVFYVVTVIL 246
>gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens]
Length = 2454
Score = 74.3 bits (181), Expect = 6e-13
Identities = 60/225 (26%), Positives = 98/225 (43%), Gaps = 34/225 (15%)
Query: 684 EVRLAKEKEEESLNQGARAQPQAKAESKPEEEEPAKLPAVTVTPAPVPDIKGDQ-KENPG 742
E R+AK+ E + + ++ +PEE + G Q +ENPG
Sbjct: 1230 ENRIAKKMLLEEIKANLSSDEDGSSDDEPEEGKKRT---------------GKQNEENPG 1274
Query: 743 GQEDVAEAESTGEMPGEEGE-------------TAGEGET--EEKSGGETQPEGEGETET 787
+E + S + EE + T +GE+ E+K+ + E +G
Sbjct: 1275 DEEAKNQVNSESDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRR 1334
Query: 788 QGKGEECEDENEAEGKGDNEGEDEGEIHAEDGEMKGNEGETESQELSAENHGEAKNDEKG 847
+ E+ ED + E G +E E E + E E + S + + K
Sbjct: 1335 KVSSEDSEDSDFQES-GVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQ--KKKRRRIK 1391
Query: 848 VEDGGGSDGGDSEEEEEEEEEQEEEEEEEEQEEEEEEEEEEEEKG 892
V++ S+ + EEEEEE+E+EEEEEEEE+EEEE+E ++ + G
Sbjct: 1392 VQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPG 1436
Score = 49.7 bits (117), Expect = 2e-05
Identities = 49/215 (22%), Positives = 93/215 (43%), Gaps = 42/215 (19%)
Query: 686 RLAKEKEEESLNQGARAQPQAKAESKPEE-EEPAKLPAVTVTPAPVPDIK-GDQKENPGG 743
R K+ EE ++ A+ Q ++++S EE ++P + V D + G++K+
Sbjct: 1264 RTGKQNEENPGDEEAKNQVNSESDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKPK 1323
Query: 744 QEDVAEAESTGEMPGEEGETAG---EGETEEKSGGETQPEGEGETETQGKGEECEDENEA 800
+ + + ++ E+ E + G +EE S E++ E T + K E E++
Sbjct: 1324 EHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVS--ESEDEQRPRTRSAKKAELEENQRSY 1381
Query: 801 EGKGDNEGEDEGEIHAEDGEMKGNEGETESQELSAENHGEAKNDEKGVEDGGGSDGGDSE 860
+ K + I ++ N+ +E +
Sbjct: 1382 KQK-----KKRRRIKVQEDSSSENKSNSEEE----------------------------- 1407
Query: 861 EEEEEEEEQEEEEEEEEQEEEEEEEEEEEEKGNEE 895
EEE+EEE+EEEEEEEE+EE+E ++ + KG ++
Sbjct: 1408 -EEEKEEEEEEEEEEEEEEEDENDDSKSPGKGRKK 1441
Score = 38.9 bits (89), Expect = 0.027
Identities = 40/200 (20%), Positives = 80/200 (40%), Gaps = 13/200 (6%)
Query: 691 KEEESLNQGARAQPQAKAESKPEEEEPAKLPAVTVTPAPVPDIKGDQKENPGGQEDVAEA 750
KE +S + + A+ ++ K ++ +K AV V ++ K Q D+ +
Sbjct: 1109 KEIQSGSSSSDAEESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRK---QADITSS 1165
Query: 751 ESTGEMPGEEGETAGEGETEEKSGGETQPEGEGETETQGKGEECEDENEAEGKGDNEGED 810
S+ ++ ++ + GEG ++E+ + +P E + G +EA K D
Sbjct: 1166 SSS-DIEDDDQNSIGEGSSDEQ---KIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVD 1221
Query: 811 EGEIHAEDGEMKGNEGETESQELSAENHGEAKNDEKGVEDGGGSDGGDSEEEEEEEEEQE 870
+ D + E + L E +DE G D +G ++ EE +
Sbjct: 1222 D------DDDDNDPENRIAKKMLLEEIKANLSSDEDGSSDDEPEEGKKRTGKQNEENPGD 1275
Query: 871 EEEEEEEQEEEEEEEEEEEE 890
EE + + E + + EE ++
Sbjct: 1276 EEAKNQVNSESDSDSEESKK 1295
Score = 36.2 bits (82), Expect = 0.18
Identities = 47/270 (17%), Positives = 102/270 (37%), Gaps = 44/270 (16%)
Query: 638 VDELQDNKKLKLPSLLTRGSSSTSLHNSTIRSTIYQLMLHSLDPLREVRLAKEKEEESLN 697
VD+L K+ SL R + T + +++ + + L + E L K++ +E+
Sbjct: 883 VDKLS-GKEQSFTSLEVRKVAETKEKSKHLKTKTCKKVQDGLSDIAEKFLKKDQSDETSE 941
Query: 698 QGARAQPQAKAESKPEEEEPAKLPAVTVTPAPVPDIKGDQK--ENPGGQEDVAEAESTGE 755
+ + E K + K+ IK +Q+ + G E + E E
Sbjct: 942 DDKKQSKKGTEEKKKPSDFKKKV------------IKMEQQYESSSDGTEKLPEREEICH 989
Query: 756 MPG-----EEGETAGEGETE---EKSGGETQPEGEGETETQGKGEECEDENEAE------ 801
P + G T GE +++ +K+ + + ++ GKG+ C+ + +
Sbjct: 990 FPKGIKQIKNGTTDGEKKSKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSEDKKSKNGAY 1049
Query: 802 ----------GKGDNEGEDEGEIHAEDGEMK-----GNEGETESQELSAENHGEAKNDEK 846
GK + +D E MK ++ + EL + +K + K
Sbjct: 1050 GREKKRCKLLGKSSRKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNLSSKRNTK 1109
Query: 847 GVEDGGGSDGGDSEEEEEEEEEQEEEEEEE 876
++ G S + E+ ++++Q +++
Sbjct: 1110 EIQSGSSSSDAEESSEDNKKKKQRTSSKKK 1139
Score = 32.3 bits (72), Expect = 2.5
Identities = 34/208 (16%), Positives = 81/208 (38%), Gaps = 20/208 (9%)
Query: 689 KEKEEESLNQGARAQPQAKAESKPEEEEPAKLPAVTVTPAPVPDIKG-----DQKENPGG 743
++ + ES N + + + K+ SK + A T +P+ K D+K + G
Sbjct: 770 RQTQSESSNYDSELEKEIKSMSK--------IGAARTTKKRIPNTKDFDSSEDEKHSKKG 821
Query: 744 QEDVAEAESTGEMPGEEGETAGEGETEEKSGGETQPEGEGETETQGKGEECEDENEAEGK 803
++ G + + + E K ET EG + E D + +
Sbjct: 822 MDN------QGHKNLKTSQEGSSDDAERKQERETFSSAEGTVDKDTTIMELRDRLPKKQQ 875
Query: 804 GDNEGEDEGEIHAEDGEMKGNEGETESQELSAENHGEAKNDEKGVEDGGGSDGGDSEEEE 863
+ ++ ++ E ++ H + K +K V+DG +++
Sbjct: 876 ASASTDGVDKLSGKEQSFTSLEVRKVAETKEKSKHLKTKTCKK-VQDGLSDIAEKFLKKD 934
Query: 864 EEEEEQEEEEEEEEQEEEEEEEEEEEEK 891
+ +E E+++++ ++ EE+++ + +K
Sbjct: 935 QSDETSEDDKKQSKKGTEEKKKPSDFKK 962
>gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens]
Length = 2492
Score = 74.3 bits (181), Expect = 6e-13
Identities = 60/225 (26%), Positives = 98/225 (43%), Gaps = 34/225 (15%)
Query: 684 EVRLAKEKEEESLNQGARAQPQAKAESKPEEEEPAKLPAVTVTPAPVPDIKGDQ-KENPG 742
E R+AK+ E + + ++ +PEE + G Q +ENPG
Sbjct: 1268 ENRIAKKMLLEEIKANLSSDEDGSSDDEPEEGKKRT---------------GKQNEENPG 1312
Query: 743 GQEDVAEAESTGEMPGEEGE-------------TAGEGET--EEKSGGETQPEGEGETET 787
+E + S + EE + T +GE+ E+K+ + E +G
Sbjct: 1313 DEEAKNQVNSESDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRR 1372
Query: 788 QGKGEECEDENEAEGKGDNEGEDEGEIHAEDGEMKGNEGETESQELSAENHGEAKNDEKG 847
+ E+ ED + E G +E E E + E E + S + + K
Sbjct: 1373 KVSSEDSEDSDFQES-GVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQ--KKKRRRIK 1429
Query: 848 VEDGGGSDGGDSEEEEEEEEEQEEEEEEEEQEEEEEEEEEEEEKG 892
V++ S+ + EEEEEE+E+EEEEEEEE+EEEE+E ++ + G
Sbjct: 1430 VQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPG 1474
Score = 49.7 bits (117), Expect = 2e-05
Identities = 49/215 (22%), Positives = 93/215 (43%), Gaps = 42/215 (19%)
Query: 686 RLAKEKEEESLNQGARAQPQAKAESKPEE-EEPAKLPAVTVTPAPVPDIK-GDQKENPGG 743
R K+ EE ++ A+ Q ++++S EE ++P + V D + G++K+
Sbjct: 1302 RTGKQNEENPGDEEAKNQVNSESDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKPK 1361
Query: 744 QEDVAEAESTGEMPGEEGETAG---EGETEEKSGGETQPEGEGETETQGKGEECEDENEA 800
+ + + ++ E+ E + G +EE S E++ E T + K E E++
Sbjct: 1362 EHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVS--ESEDEQRPRTRSAKKAELEENQRSY 1419
Query: 801 EGKGDNEGEDEGEIHAEDGEMKGNEGETESQELSAENHGEAKNDEKGVEDGGGSDGGDSE 860
+ K + I ++ N+ +E +
Sbjct: 1420 KQK-----KKRRRIKVQEDSSSENKSNSEEE----------------------------- 1445
Query: 861 EEEEEEEEQEEEEEEEEQEEEEEEEEEEEEKGNEE 895
EEE+EEE+EEEEEEEE+EE+E ++ + KG ++
Sbjct: 1446 -EEEKEEEEEEEEEEEEEEEDENDDSKSPGKGRKK 1479
Score = 38.9 bits (89), Expect = 0.027
Identities = 40/200 (20%), Positives = 80/200 (40%), Gaps = 13/200 (6%)
Query: 691 KEEESLNQGARAQPQAKAESKPEEEEPAKLPAVTVTPAPVPDIKGDQKENPGGQEDVAEA 750
KE +S + + A+ ++ K ++ +K AV V ++ K Q D+ +
Sbjct: 1147 KEIQSGSSSSDAEESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRK---QADITSS 1203
Query: 751 ESTGEMPGEEGETAGEGETEEKSGGETQPEGEGETETQGKGEECEDENEAEGKGDNEGED 810
S+ ++ ++ + GEG ++E+ + +P E + G +EA K D
Sbjct: 1204 SSS-DIEDDDQNSIGEGSSDEQ---KIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVD 1259
Query: 811 EGEIHAEDGEMKGNEGETESQELSAENHGEAKNDEKGVEDGGGSDGGDSEEEEEEEEEQE 870
+ D + E + L E +DE G D +G ++ EE +
Sbjct: 1260 D------DDDDNDPENRIAKKMLLEEIKANLSSDEDGSSDDEPEEGKKRTGKQNEENPGD 1313
Query: 871 EEEEEEEQEEEEEEEEEEEE 890
EE + + E + + EE ++
Sbjct: 1314 EEAKNQVNSESDSDSEESKK 1333
Score = 36.2 bits (82), Expect = 0.18
Identities = 47/270 (17%), Positives = 102/270 (37%), Gaps = 44/270 (16%)
Query: 638 VDELQDNKKLKLPSLLTRGSSSTSLHNSTIRSTIYQLMLHSLDPLREVRLAKEKEEESLN 697
VD+L K+ SL R + T + +++ + + L + E L K++ +E+
Sbjct: 921 VDKLS-GKEQSFTSLEVRKVAETKEKSKHLKTKTCKKVQDGLSDIAEKFLKKDQSDETSE 979
Query: 698 QGARAQPQAKAESKPEEEEPAKLPAVTVTPAPVPDIKGDQK--ENPGGQEDVAEAESTGE 755
+ + E K + K+ IK +Q+ + G E + E E
Sbjct: 980 DDKKQSKKGTEEKKKPSDFKKKV------------IKMEQQYESSSDGTEKLPEREEICH 1027
Query: 756 MPG-----EEGETAGEGETE---EKSGGETQPEGEGETETQGKGEECEDENEAE------ 801
P + G T GE +++ +K+ + + ++ GKG+ C+ + +
Sbjct: 1028 FPKGIKQIKNGTTDGEKKSKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSEDKKSKNGAY 1087
Query: 802 ----------GKGDNEGEDEGEIHAEDGEMK-----GNEGETESQELSAENHGEAKNDEK 846
GK + +D E MK ++ + EL + +K + K
Sbjct: 1088 GREKKRCKLLGKSSRKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNLSSKRNTK 1147
Query: 847 GVEDGGGSDGGDSEEEEEEEEEQEEEEEEE 876
++ G S + E+ ++++Q +++
Sbjct: 1148 EIQSGSSSSDAEESSEDNKKKKQRTSSKKK 1177
Score = 32.3 bits (72), Expect = 2.5
Identities = 34/208 (16%), Positives = 81/208 (38%), Gaps = 20/208 (9%)
Query: 689 KEKEEESLNQGARAQPQAKAESKPEEEEPAKLPAVTVTPAPVPDIKG-----DQKENPGG 743
++ + ES N + + + K+ SK + A T +P+ K D+K + G
Sbjct: 808 RQTQSESSNYDSELEKEIKSMSK--------IGAARTTKKRIPNTKDFDSSEDEKHSKKG 859
Query: 744 QEDVAEAESTGEMPGEEGETAGEGETEEKSGGETQPEGEGETETQGKGEECEDENEAEGK 803
++ G + + + E K ET EG + E D + +
Sbjct: 860 MDN------QGHKNLKTSQEGSSDDAERKQERETFSSAEGTVDKDTTIMELRDRLPKKQQ 913
Query: 804 GDNEGEDEGEIHAEDGEMKGNEGETESQELSAENHGEAKNDEKGVEDGGGSDGGDSEEEE 863
+ ++ ++ E ++ H + K +K V+DG +++
Sbjct: 914 ASASTDGVDKLSGKEQSFTSLEVRKVAETKEKSKHLKTKTCKK-VQDGLSDIAEKFLKKD 972
Query: 864 EEEEEQEEEEEEEEQEEEEEEEEEEEEK 891
+ +E E+++++ ++ EE+++ + +K
Sbjct: 973 QSDETSEDDKKQSKKGTEEKKKPSDFKK 1000
>gi|157738649 neurofilament, medium polypeptide 150kDa isoform 1
[Homo sapiens]
Length = 916
Score = 72.8 bits (177), Expect = 2e-12
Identities = 65/265 (24%), Positives = 117/265 (44%), Gaps = 46/265 (17%)
Query: 684 EVRLAKEKEEESLNQGARAQPQAKAESKPEEEEPAKLPAVTVTPAPVPDIKGDQKENPGG 743
E+ ++ ++E++ + +P+A+ EEE AK V T V + +G+++E G
Sbjct: 479 ELAVSMKEEKKEAAEEKEEEPEAE-----EEEVAAKKSPVKATAPEVKEEEGEKEEEEGQ 533
Query: 744 QEDVAEAESTGEMPGEEGETAGEGETEEKSGGETQPEGEGETETQGKGEECEDENEAEGK 803
+E+ E E EEG + EG +E++ G Q EGE E E +G+ E ++E + E K
Sbjct: 534 EEEEEEDEGAKSDQAEEGGSEKEGSSEKEEG--EQEEGETEAEAEGEEAEAKEEKKVEEK 591
Query: 804 GDNEGEDE---------------GEIHAEDGEMKGN----------EGETESQELSAENH 838
+ E + E KG +G++ + E
Sbjct: 592 SEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEK 651
Query: 839 GEAKNDEKGVEDGGGSDGGDSEEEEE----------EEEEQEEE----EEEEEQEEEEEE 884
G++ + VE+ G S S EE+ EE + + E E++EE+E+E +E
Sbjct: 652 GKSPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKE 711
Query: 885 EEEEEEKGNEEPLSLDWPETRQKQA 909
+EE+ +E D PE ++ ++
Sbjct: 712 APKEEKVEKKEEKPKDVPEKKKAES 736
Score = 63.9 bits (154), Expect = 8e-10
Identities = 50/148 (33%), Positives = 70/148 (47%), Gaps = 11/148 (7%)
Query: 762 ETAGEGETEEKSGGETQPEGEGETETQGKGEECEDENEAEGKGDNE--GEDEGEIHAEDG 819
ET E E E T E + + +E +E E E + + E + + A
Sbjct: 459 ETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAP 518
Query: 820 EMKGNEGETESQELSAENHGE---AKNDEKGVEDGGGSDGGDSEEEEEEEEEQEEEEEEE 876
E+K EGE E +E E E AK+D+ E+GG G SE+EE E+EE E E E E
Sbjct: 519 EVKEEEGEKEEEEGQEEEEEEDEGAKSDQ--AEEGGSEKEGSSEKEEGEQEEGETEAEAE 576
Query: 877 EQE----EEEEEEEEEEEKGNEEPLSLD 900
+E EE++ EE+ EE +E L D
Sbjct: 577 GEEAEAKEEKKVEEKSEEVATKEELVAD 604
Score = 56.2 bits (134), Expect = 2e-07
Identities = 49/184 (26%), Positives = 81/184 (44%), Gaps = 29/184 (15%)
Query: 709 ESKPEEEEPAKLPAVT-VTPAPVPDIKGDQKENPGGQEDVAEAESTGEMPGEEGETAGEG 767
E+K E+E+ A+T +T +K ++KE +E+ EAE + A
Sbjct: 459 ETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAP 518
Query: 768 ETEEKSGGETQPEGEGETETQGKGEECEDENEAEGKGDNEGEDEGEIHAEDGEMKGNEGE 827
E +E+ G + + EG+ E E + +G + + EG + EG E E EGE
Sbjct: 519 EVKEEEGEKEEEEGQEEEEEEDEG--AKSDQAEEGGSEKEGSSEKE-----------EGE 565
Query: 828 TESQELSAENHGEAKNDEKGVEDGGGSDGGDSEEEEEEEEEQEEEEEEEEQEEEEEEEEE 887
E E AE GE +++EE++ EE+ EE +EE + + E+
Sbjct: 566 QEEGETEAEAEGEE---------------AEAKEEKKVEEKSEEVATKEELVADAKVEKP 610
Query: 888 EEEK 891
E+ K
Sbjct: 611 EKAK 614
Score = 55.5 bits (132), Expect = 3e-07
Identities = 50/184 (27%), Positives = 75/184 (40%), Gaps = 27/184 (14%)
Query: 711 KPEEEEPAKLPAVTVTPAPVPDIKGDQKENPGGQEDVAEAESTGEMPGEEGETAGEGETE 770
KP+ E P + + K + +++ + A E EE + A E + E
Sbjct: 438 KPKVEAPKLKVQHKFVEEIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEE 497
Query: 771 EKSGGETQPEGEGETETQGKGEECEDENEAEGKGDNEGEDEGEIHAEDGEMKGNEGETES 830
E E + + E E+E E E + EG++E E
Sbjct: 498 EPEAEEEEVAAKKSPVKATAPEVKEEEGEKE---EEEGQEEEE----------------- 537
Query: 831 QELSAENHGEAKNDEKGVEDGGGSDGGDSEEEEEEEEEQEEEEEEEEQEEEEEEEEEEEE 890
E AK+D+ E+GG G SE+EE E+EE E E E E +E E +EE++ EE
Sbjct: 538 -----EEDEGAKSDQ--AEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEE 590
Query: 891 KGNE 894
K E
Sbjct: 591 KSEE 594
Score = 53.5 bits (127), Expect = 1e-06
Identities = 60/249 (24%), Positives = 103/249 (41%), Gaps = 39/249 (15%)
Query: 684 EVRLAKEKEEESLNQGARAQPQAKAESKPEEEEPAKLPAVTVTP------APVPDIKGDQ 737
E +EK+ E ++ + + A++K E+ E AK P V +P +PVP ++
Sbjct: 579 EAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSP-VPKSPVEEKGKSPVPKSPVEE 637
Query: 738 KENPGGQEDVAEAESTGEMPGEEGETAGEG-------ETEEKSGGETQPEGEGETETQ-G 789
K + E + +P E G+ E + KS P E +++ + G
Sbjct: 638 KGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVG 697
Query: 790 KGEECEDENEA--EGKGDNEGEDEGEIHAEDGEMKGNEGETESQ---------------- 831
KGE+ E+E + E + + E + E + E K E + +
Sbjct: 698 KGEQKEEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITKSVKVHL 757
Query: 832 ELSAENHGEAKNDEKGVEDGGGSDGGDSEEEEEEEEEQEEEEE-----EEEQEEEEEEEE 886
E + G+ EK E GG +GG EE ++ + +E+ E E +EE E+E
Sbjct: 758 EKETKEEGKPLQQEKEKEKAGG-EGGSEEEGSDKGAKGSRKEDIAVNGEVEGKEEVEQET 816
Query: 887 EEEEKGNEE 895
+E+ G EE
Sbjct: 817 KEKGSGREE 825
Score = 47.8 bits (112), Expect = 6e-05
Identities = 36/119 (30%), Positives = 61/119 (51%), Gaps = 6/119 (5%)
Query: 792 EECEDENEAEGKGDNEGEDEGEIHA--EDGEMKGNEGETESQELSAENHGEAKNDEKGVE 849
EE +E + E D + E E + A E+ + E + E+ E E EA+ +E +
Sbjct: 454 EEIIEETKVE---DEKSEMEEALTAITEELAVSMKEEKKEAAE-EKEEEPEAEEEEVAAK 509
Query: 850 DGGGSDGGDSEEEEEEEEEQEEEEEEEEQEEEEEEEEEEEEKGNEEPLSLDWPETRQKQ 908
+EEE E+E+EE +EEEE+E+E + ++ EE G+E+ S + E Q++
Sbjct: 510 KSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEE 568
Score = 47.8 bits (112), Expect = 6e-05
Identities = 54/201 (26%), Positives = 85/201 (42%), Gaps = 16/201 (7%)
Query: 683 REVRLA-KEKEEESLNQGARAQPQAKAESKPEEEEPAKLPAVTVTPAPVPDIKGDQKENP 741
+EV+ A KE++ E + + P+ K P +EE A VT+T + ++ + KE
Sbjct: 707 KEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKEE-AVAEVVTITKSVKVHLEKETKEEG 765
Query: 742 GGQEDVAEAESTGEMPGEEGETAGEGETEEKSGGETQPEGEGETETQGKGE-ECEDENEA 800
+ E E G GEG +EE+ G + +G + + GE E ++E E
Sbjct: 766 KPLQQEKEKEKAG----------GEGGSEEE-GSDKGAKGSRKEDIAVNGEVEGKEEVEQ 814
Query: 801 EGKGDNEGEDEGEIHAEDGEMKGNEGETESQELSAENHGEAKNDEKGVEDGGGSDGGDSE 860
E K G +E + +G E + + S E K EK +GG DG
Sbjct: 815 ETKEKGSGREEEKGVVTNGLDLSPADEKKGGDKSEEKVVVTKTVEKITSEGG--DGATKY 872
Query: 861 EEEEEEEEQEEEEEEEEQEEE 881
+ Q+ EE EE EE+
Sbjct: 873 ITKSVTVTQKVEEHEETFEEK 893
Score = 45.4 bits (106), Expect = 3e-04
Identities = 53/234 (22%), Positives = 97/234 (41%), Gaps = 23/234 (9%)
Query: 690 EKEEESLNQGARAQPQAKAESKPEE----EE---PAKLPAVTVTPAPVPDIKGDQKENPG 742
E E E+ + A A+ + K E K EE EE AK+ +PVP ++K
Sbjct: 570 ETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSP 629
Query: 743 GQEDVAEAESTGEMPGEEGETAGEG-------ETEEKSGGETQPEGEGETETQGKGEECE 795
+ E + +P E G+ E + KS P E K E
Sbjct: 630 VPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEE 689
Query: 796 DENEAE-GKGDNEGEDEGEIHAEDGEMKGNEGETESQELSAENHGEAKNDEKGVED---- 850
+++AE GKG+ + E+E E+ E K + E + +++ + E+ E+ V +
Sbjct: 690 AKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKEEAVAEVVTI 749
Query: 851 ----GGGSDGGDSEEEEEEEEEQEEEEEEEEQEEEEEEEEEEEEKGNEEPLSLD 900
+ EE + ++E+E+E+ E EEE ++ + +E ++++
Sbjct: 750 TKSVKVHLEKETKEEGKPLQQEKEKEKAGGEGGSEEEGSDKGAKGSRKEDIAVN 803
Score = 43.9 bits (102), Expect = 8e-04
Identities = 50/193 (25%), Positives = 79/193 (40%), Gaps = 22/193 (11%)
Query: 710 SKPEEEEPAKLPAVTVTPAPVPDIKGDQKENPGGQEDVAEAESTGEMPGEEGETAGEGET 769
SK EE AK P V +PV + K + G Q++ E E E P EE E +
Sbjct: 670 SKSPVEEKAKSP---VPKSPVEEAKSKAEVGKGEQKEEEEKE-VKEAPKEEKVEKKEEKP 725
Query: 770 E---EKSGGETQPEGEGETE----TQGKGEECEDENEAEGKGDNEGEDEGEIHAEDGEMK 822
+ EK E+ + E E T+ E E + EGK + +++ E
Sbjct: 726 KDVPEKKKAESPVKEEAVAEVVTITKSVKVHLEKETKEEGKPLQQEKEK--------EKA 777
Query: 823 GNEGETESQELSAENHGEAKNDEKGVEDGGGSDGGDSEEEEEEEEEQEEEEEEEEQEEEE 882
G EG +E + G K D + G +G + E+E +E+ EEE+
Sbjct: 778 GGEGGSEEEGSDKGAKGSRKED---IAVNGEVEGKEEVEQETKEKGSGREEEKGVVTNGL 834
Query: 883 EEEEEEEEKGNEE 895
+ +E+KG ++
Sbjct: 835 DLSPADEKKGGDK 847
Score = 43.1 bits (100), Expect = 0.001
Identities = 55/233 (23%), Positives = 97/233 (41%), Gaps = 30/233 (12%)
Query: 688 AKEKEEESLNQG---ARAQ-PQAKAESKPEEEE-------------PAKLPAVTVTPAPV 730
+ EKEE +G A A+ +A+A+ + + EE AK+ +PV
Sbjct: 558 SSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPV 617
Query: 731 PDIKGDQKENPGGQEDVAEAESTGEMPGEEGETAGEG-------ETEEKSGGETQPEGEG 783
P ++K + E + +P E G+ E + KS P E
Sbjct: 618 PKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSPVEEK 677
Query: 784 ETETQGKGEECEDENEAE-GKGDNEGEDEGEIHAEDGEMKGNEGETESQELSAENHGEAK 842
K E +++AE GKG+ + E+E E+ E K E +E ++ E K
Sbjct: 678 AKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEEK-----VEKKEEKPKDVPEKK 732
Query: 843 NDEKGVEDGGGSDGGDSEEEEEEEEEQEEEEEEEEQEEEEEEEEEEEEKGNEE 895
E V++ ++ + + E+E +EE + ++E+E+E+ E G+EE
Sbjct: 733 KAESPVKEEAVAEVVTITKSVKVHLEKETKEEGKPLQQEKEKEKAGGEGGSEE 785
Score = 40.4 bits (93), Expect = 0.009
Identities = 40/164 (24%), Positives = 67/164 (40%), Gaps = 26/164 (15%)
Query: 689 KEKEEESLNQGARAQPQAKAESKPEE-------EEPAKLPAV----TVTPAPVPDIKGDQ 737
KE+EE+ + + + + K E KP++ E P K AV T+T + ++ +
Sbjct: 702 KEEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITKSVKVHLEKET 761
Query: 738 KENPGGQEDVAEAESTGEMPGEEGETA---------------GEGETEEKSGGETQPEGE 782
KE + E E G G E E + GE E +E+ ET+ +G
Sbjct: 762 KEEGKPLQQEKEKEKAGGEGGSEEEGSDKGAKGSRKEDIAVNGEVEGKEEVEQETKEKGS 821
Query: 783 GETETQGKGEECEDENEAEGKGDNEGEDEGEIHAEDGEMKGNEG 826
G E +G D + A+ K + +E + + E +EG
Sbjct: 822 GREEEKGVVTNGLDLSPADEKKGGDKSEEKVVVTKTVEKITSEG 865
>gi|157738641 neurofilament, medium polypeptide 150kDa isoform 2
[Homo sapiens]
Length = 540
Score = 72.8 bits (177), Expect = 2e-12
Identities = 65/265 (24%), Positives = 117/265 (44%), Gaps = 46/265 (17%)
Query: 684 EVRLAKEKEEESLNQGARAQPQAKAESKPEEEEPAKLPAVTVTPAPVPDIKGDQKENPGG 743
E+ ++ ++E++ + +P+A+ EEE AK V T V + +G+++E G
Sbjct: 103 ELAVSMKEEKKEAAEEKEEEPEAE-----EEEVAAKKSPVKATAPEVKEEEGEKEEEEGQ 157
Query: 744 QEDVAEAESTGEMPGEEGETAGEGETEEKSGGETQPEGEGETETQGKGEECEDENEAEGK 803
+E+ E E EEG + EG +E++ G Q EGE E E +G+ E ++E + E K
Sbjct: 158 EEEEEEDEGAKSDQAEEGGSEKEGSSEKEEG--EQEEGETEAEAEGEEAEAKEEKKVEEK 215
Query: 804 GDNEGEDE---------------GEIHAEDGEMKGN----------EGETESQELSAENH 838
+ E + E KG +G++ + E
Sbjct: 216 SEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEK 275
Query: 839 GEAKNDEKGVEDGGGSDGGDSEEEEE----------EEEEQEEE----EEEEEQEEEEEE 884
G++ + VE+ G S S EE+ EE + + E E++EE+E+E +E
Sbjct: 276 GKSPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKE 335
Query: 885 EEEEEEKGNEEPLSLDWPETRQKQA 909
+EE+ +E D PE ++ ++
Sbjct: 336 APKEEKVEKKEEKPKDVPEKKKAES 360
Score = 63.9 bits (154), Expect = 8e-10
Identities = 50/148 (33%), Positives = 70/148 (47%), Gaps = 11/148 (7%)
Query: 762 ETAGEGETEEKSGGETQPEGEGETETQGKGEECEDENEAEGKGDNE--GEDEGEIHAEDG 819
ET E E E T E + + +E +E E E + + E + + A
Sbjct: 83 ETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAP 142
Query: 820 EMKGNEGETESQELSAENHGE---AKNDEKGVEDGGGSDGGDSEEEEEEEEEQEEEEEEE 876
E+K EGE E +E E E AK+D+ E+GG G SE+EE E+EE E E E E
Sbjct: 143 EVKEEEGEKEEEEGQEEEEEEDEGAKSDQ--AEEGGSEKEGSSEKEEGEQEEGETEAEAE 200
Query: 877 EQE----EEEEEEEEEEEKGNEEPLSLD 900
+E EE++ EE+ EE +E L D
Sbjct: 201 GEEAEAKEEKKVEEKSEEVATKEELVAD 228
Score = 56.2 bits (134), Expect = 2e-07
Identities = 49/184 (26%), Positives = 81/184 (44%), Gaps = 29/184 (15%)
Query: 709 ESKPEEEEPAKLPAVT-VTPAPVPDIKGDQKENPGGQEDVAEAESTGEMPGEEGETAGEG 767
E+K E+E+ A+T +T +K ++KE +E+ EAE + A
Sbjct: 83 ETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEEEPEAEEEEVAAKKSPVKATAP 142
Query: 768 ETEEKSGGETQPEGEGETETQGKGEECEDENEAEGKGDNEGEDEGEIHAEDGEMKGNEGE 827
E +E+ G + + EG+ E E + +G + + EG + EG E E EGE
Sbjct: 143 EVKEEEGEKEEEEGQEEEEEEDEG--AKSDQAEEGGSEKEGSSEKE-----------EGE 189
Query: 828 TESQELSAENHGEAKNDEKGVEDGGGSDGGDSEEEEEEEEEQEEEEEEEEQEEEEEEEEE 887
E E AE GE +++EE++ EE+ EE +EE + + E+
Sbjct: 190 QEEGETEAEAEGEE---------------AEAKEEKKVEEKSEEVATKEELVADAKVEKP 234
Query: 888 EEEK 891
E+ K
Sbjct: 235 EKAK 238
Score = 55.5 bits (132), Expect = 3e-07
Identities = 50/184 (27%), Positives = 75/184 (40%), Gaps = 27/184 (14%)
Query: 711 KPEEEEPAKLPAVTVTPAPVPDIKGDQKENPGGQEDVAEAESTGEMPGEEGETAGEGETE 770
KP+ E P + + K + +++ + A E EE + A E + E
Sbjct: 62 KPKVEAPKLKVQHKFVEEIIEETKVEDEKSEMEEALTAITEELAVSMKEEKKEAAEEKEE 121
Query: 771 EKSGGETQPEGEGETETQGKGEECEDENEAEGKGDNEGEDEGEIHAEDGEMKGNEGETES 830
E E + + E E+E E E + EG++E E
Sbjct: 122 EPEAEEEEVAAKKSPVKATAPEVKEEEGEKE---EEEGQEEEE----------------- 161
Query: 831 QELSAENHGEAKNDEKGVEDGGGSDGGDSEEEEEEEEEQEEEEEEEEQEEEEEEEEEEEE 890
E AK+D+ E+GG G SE+EE E+EE E E E E +E E +EE++ EE
Sbjct: 162 -----EEDEGAKSDQ--AEEGGSEKEGSSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEE 214
Query: 891 KGNE 894
K E
Sbjct: 215 KSEE 218
Score = 53.5 bits (127), Expect = 1e-06
Identities = 60/249 (24%), Positives = 103/249 (41%), Gaps = 39/249 (15%)
Query: 684 EVRLAKEKEEESLNQGARAQPQAKAESKPEEEEPAKLPAVTVTP------APVPDIKGDQ 737
E +EK+ E ++ + + A++K E+ E AK P V +P +PVP ++
Sbjct: 203 EAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSP-VPKSPVEEKGKSPVPKSPVEE 261
Query: 738 KENPGGQEDVAEAESTGEMPGEEGETAGEG-------ETEEKSGGETQPEGEGETETQ-G 789
K + E + +P E G+ E + KS P E +++ + G
Sbjct: 262 KGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEEAKSKAEVG 321
Query: 790 KGEECEDENEA--EGKGDNEGEDEGEIHAEDGEMKGNEGETESQ---------------- 831
KGE+ E+E + E + + E + E + E K E + +
Sbjct: 322 KGEQKEEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITKSVKVHL 381
Query: 832 ELSAENHGEAKNDEKGVEDGGGSDGGDSEEEEEEEEEQEEEEE-----EEEQEEEEEEEE 886
E + G+ EK E GG +GG EE ++ + +E+ E E +EE E+E
Sbjct: 382 EKETKEEGKPLQQEKEKEKAGG-EGGSEEEGSDKGAKGSRKEDIAVNGEVEGKEEVEQET 440
Query: 887 EEEEKGNEE 895
+E+ G EE
Sbjct: 441 KEKGSGREE 449
Score = 47.8 bits (112), Expect = 6e-05
Identities = 36/119 (30%), Positives = 61/119 (51%), Gaps = 6/119 (5%)
Query: 792 EECEDENEAEGKGDNEGEDEGEIHA--EDGEMKGNEGETESQELSAENHGEAKNDEKGVE 849
EE +E + E D + E E + A E+ + E + E+ E E EA+ +E +
Sbjct: 78 EEIIEETKVE---DEKSEMEEALTAITEELAVSMKEEKKEAAE-EKEEEPEAEEEEVAAK 133
Query: 850 DGGGSDGGDSEEEEEEEEEQEEEEEEEEQEEEEEEEEEEEEKGNEEPLSLDWPETRQKQ 908
+EEE E+E+EE +EEEE+E+E + ++ EE G+E+ S + E Q++
Sbjct: 134 KSPVKATAPEVKEEEGEKEEEEGQEEEEEEDEGAKSDQAEEGGSEKEGSSEKEEGEQEE 192
Score = 47.8 bits (112), Expect = 6e-05
Identities = 54/201 (26%), Positives = 85/201 (42%), Gaps = 16/201 (7%)
Query: 683 REVRLA-KEKEEESLNQGARAQPQAKAESKPEEEEPAKLPAVTVTPAPVPDIKGDQKENP 741
+EV+ A KE++ E + + P+ K P +EE A VT+T + ++ + KE
Sbjct: 331 KEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKEE-AVAEVVTITKSVKVHLEKETKEEG 389
Query: 742 GGQEDVAEAESTGEMPGEEGETAGEGETEEKSGGETQPEGEGETETQGKGE-ECEDENEA 800
+ E E G GEG +EE+ G + +G + + GE E ++E E
Sbjct: 390 KPLQQEKEKEKAG----------GEGGSEEE-GSDKGAKGSRKEDIAVNGEVEGKEEVEQ 438
Query: 801 EGKGDNEGEDEGEIHAEDGEMKGNEGETESQELSAENHGEAKNDEKGVEDGGGSDGGDSE 860
E K G +E + +G E + + S E K EK +GG DG
Sbjct: 439 ETKEKGSGREEEKGVVTNGLDLSPADEKKGGDKSEEKVVVTKTVEKITSEGG--DGATKY 496
Query: 861 EEEEEEEEQEEEEEEEEQEEE 881
+ Q+ EE EE EE+
Sbjct: 497 ITKSVTVTQKVEEHEETFEEK 517
Score = 45.4 bits (106), Expect = 3e-04
Identities = 53/234 (22%), Positives = 97/234 (41%), Gaps = 23/234 (9%)
Query: 690 EKEEESLNQGARAQPQAKAESKPEE----EE---PAKLPAVTVTPAPVPDIKGDQKENPG 742
E E E+ + A A+ + K E K EE EE AK+ +PVP ++K
Sbjct: 194 ETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPVPKSPVEEKGKSP 253
Query: 743 GQEDVAEAESTGEMPGEEGETAGEG-------ETEEKSGGETQPEGEGETETQGKGEECE 795
+ E + +P E G+ E + KS P E K E
Sbjct: 254 VPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSPVEEKAKSPVPKSPVEE 313
Query: 796 DENEAE-GKGDNEGEDEGEIHAEDGEMKGNEGETESQELSAENHGEAKNDEKGVED---- 850
+++AE GKG+ + E+E E+ E K + E + +++ + E+ E+ V +
Sbjct: 314 AKSKAEVGKGEQKEEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKEEAVAEVVTI 373
Query: 851 ----GGGSDGGDSEEEEEEEEEQEEEEEEEEQEEEEEEEEEEEEKGNEEPLSLD 900
+ EE + ++E+E+E+ E EEE ++ + +E ++++
Sbjct: 374 TKSVKVHLEKETKEEGKPLQQEKEKEKAGGEGGSEEEGSDKGAKGSRKEDIAVN 427
Score = 43.9 bits (102), Expect = 8e-04
Identities = 50/193 (25%), Positives = 79/193 (40%), Gaps = 22/193 (11%)
Query: 710 SKPEEEEPAKLPAVTVTPAPVPDIKGDQKENPGGQEDVAEAESTGEMPGEEGETAGEGET 769
SK EE AK P V +PV + K + G Q++ E E E P EE E +
Sbjct: 294 SKSPVEEKAKSP---VPKSPVEEAKSKAEVGKGEQKEEEEKE-VKEAPKEEKVEKKEEKP 349
Query: 770 E---EKSGGETQPEGEGETE----TQGKGEECEDENEAEGKGDNEGEDEGEIHAEDGEMK 822
+ EK E+ + E E T+ E E + EGK + +++ E
Sbjct: 350 KDVPEKKKAESPVKEEAVAEVVTITKSVKVHLEKETKEEGKPLQQEKEK--------EKA 401
Query: 823 GNEGETESQELSAENHGEAKNDEKGVEDGGGSDGGDSEEEEEEEEEQEEEEEEEEQEEEE 882
G EG +E + G K D + G +G + E+E +E+ EEE+
Sbjct: 402 GGEGGSEEEGSDKGAKGSRKED---IAVNGEVEGKEEVEQETKEKGSGREEEKGVVTNGL 458
Query: 883 EEEEEEEEKGNEE 895
+ +E+KG ++
Sbjct: 459 DLSPADEKKGGDK 471
Score = 43.1 bits (100), Expect = 0.001
Identities = 55/233 (23%), Positives = 97/233 (41%), Gaps = 30/233 (12%)
Query: 688 AKEKEEESLNQG---ARAQ-PQAKAESKPEEEE-------------PAKLPAVTVTPAPV 730
+ EKEE +G A A+ +A+A+ + + EE AK+ +PV
Sbjct: 182 SSEKEEGEQEEGETEAEAEGEEAEAKEEKKVEEKSEEVATKEELVADAKVEKPEKAKSPV 241
Query: 731 PDIKGDQKENPGGQEDVAEAESTGEMPGEEGETAGEG-------ETEEKSGGETQPEGEG 783
P ++K + E + +P E G+ E + KS P E
Sbjct: 242 PKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVPKSPVEEKGKSPVSKSPVEEK 301
Query: 784 ETETQGKGEECEDENEAE-GKGDNEGEDEGEIHAEDGEMKGNEGETESQELSAENHGEAK 842
K E +++AE GKG+ + E+E E+ E K E +E ++ E K
Sbjct: 302 AKSPVPKSPVEEAKSKAEVGKGEQKEEEEKEVKEAPKEEK-----VEKKEEKPKDVPEKK 356
Query: 843 NDEKGVEDGGGSDGGDSEEEEEEEEEQEEEEEEEEQEEEEEEEEEEEEKGNEE 895
E V++ ++ + + E+E +EE + ++E+E+E+ E G+EE
Sbjct: 357 KAESPVKEEAVAEVVTITKSVKVHLEKETKEEGKPLQQEKEKEKAGGEGGSEE 409
Score = 40.4 bits (93), Expect = 0.009
Identities = 40/164 (24%), Positives = 67/164 (40%), Gaps = 26/164 (15%)
Query: 689 KEKEEESLNQGARAQPQAKAESKPEE-------EEPAKLPAV----TVTPAPVPDIKGDQ 737
KE+EE+ + + + + K E KP++ E P K AV T+T + ++ +
Sbjct: 326 KEEEEKEVKEAPKEEKVEKKEEKPKDVPEKKKAESPVKEEAVAEVVTITKSVKVHLEKET 385
Query: 738 KENPGGQEDVAEAESTGEMPGEEGETA---------------GEGETEEKSGGETQPEGE 782
KE + E E G G E E + GE E +E+ ET+ +G
Sbjct: 386 KEEGKPLQQEKEKEKAGGEGGSEEEGSDKGAKGSRKEDIAVNGEVEGKEEVEQETKEKGS 445
Query: 783 GETETQGKGEECEDENEAEGKGDNEGEDEGEIHAEDGEMKGNEG 826
G E +G D + A+ K + +E + + E +EG
Sbjct: 446 GREEEKGVVTNGLDLSPADEKKGGDKSEEKVVVTKTVEKITSEG 489
>gi|94536805 splicing factor YT521-B isoform 2 [Homo sapiens]
Length = 709
Score = 72.0 bits (175), Expect = 3e-12
Identities = 45/130 (34%), Positives = 70/130 (53%), Gaps = 4/130 (3%)
Query: 766 EGETEEKSGGETQPEGEGETETQGKGEECEDENEAEGKGDNEGEDEGEIHAEDGEMKGNE 825
+ + E+ + PE ++ T E E + ++ E E+++E+ G++
Sbjct: 127 KNQPEKTCVRKRDPERRAKSPTPDGSERIGLEVDRRASRSSQSSKE-EVNSEE---YGSD 182
Query: 826 GETESQELSAENHGEAKNDEKGVEDGGGSDGGDSEEEEEEEEEQEEEEEEEEQEEEEEEE 885
ET S S E +N+E+GVE+ D E+ EE+EE E+ EEEEE+EEEEEEE
Sbjct: 183 HETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEE 242
Query: 886 EEEEEKGNEE 895
EEEEE+ E+
Sbjct: 243 EEEEEEEYEQ 252
Score = 70.9 bits (172), Expect = 6e-12
Identities = 74/274 (27%), Positives = 118/274 (43%), Gaps = 70/274 (25%)
Query: 615 SRRPVAKVMALEDLSKPGDGAIAVDELQDNKKLKLPSLLTRGSSSTSLHNSTIRSTIYQL 674
++R V + + +SKP +++ +NK++ + T+G S+T N + +
Sbjct: 57 TKRQKPSVHSRQLVSKPLSSSVS-----NNKRI----VSTKGKSATEYKNEEYQRSERN- 106
Query: 675 MLHSLDPLREVRLAKEKEEESLNQGARAQPQAKAESKPEEEEPAKLPAVTVTPAPVPDIK 734
LD R++RL+ E QP+ K + E AK P TP
Sbjct: 107 --KRLDADRKIRLSSSASREPYKN----QPEKTCVRKRDPERRAKSP----TP------- 149
Query: 735 GDQKENPGGQEDVAEAESTGEMPGEEGETAGEGETEEKSGGETQPEGEGETETQGKGEEC 794
D E G + D + S+ +++ E E+ G + + G ++ QG E
Sbjct: 150 -DGSERIGLEVDRRASRSS--------QSSKEEVNSEEYGSDHETGSSGSSDEQGNNTE- 199
Query: 795 EDENEAEGKGDNEGEDEGEIHAEDGEMKGNEGETESQELSAENHGEAKNDEKGVEDGGGS 854
NE EG ++ EDE E +A+ DE+ EDG
Sbjct: 200 ---NEEEGVEEDVEEDE------------------------EVEEDAEEDEEVDEDG--- 229
Query: 855 DGGDSEEEEEEEEEQEEEEEEEEQEEEEEEEEEE 888
+ EEEEEEEEE+EEEEEEEE E++E +++EE
Sbjct: 230 ---EEEEEEEEEEEEEEEEEEEEYEQDERDQKEE 260
Score = 57.4 bits (137), Expect = 7e-08
Identities = 40/128 (31%), Positives = 59/128 (46%), Gaps = 15/128 (11%)
Query: 794 CEDENEAEGKGDNEGEDEGE-IHAEDGEMKGNEGETESQELSAENHGEAKNDEKGVEDGG 852
C + + E + + D E I E ++ +E+++E +G + E G
Sbjct: 134 CVRKRDPERRAKSPTPDGSERIGLEVDRRASRSSQSSKEEVNSEEYGS--DHETGSSGSS 191
Query: 853 GSDGGDSEEEEEEEEEQEEEEEE------------EEQEEEEEEEEEEEEKGNEEPLSLD 900
G ++E EEE EE EE+EE E+ EEEEEEEEEEEE+ EE +
Sbjct: 192 DEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYE 251
Query: 901 WPETRQKQ 908
E QK+
Sbjct: 252 QDERDQKE 259
>gi|72534750 splicing factor YT521-B isoform 1 [Homo sapiens]
Length = 727
Score = 72.0 bits (175), Expect = 3e-12
Identities = 45/130 (34%), Positives = 70/130 (53%), Gaps = 4/130 (3%)
Query: 766 EGETEEKSGGETQPEGEGETETQGKGEECEDENEAEGKGDNEGEDEGEIHAEDGEMKGNE 825
+ + E+ + PE ++ T E E + ++ E E+++E+ G++
Sbjct: 127 KNQPEKTCVRKRDPERRAKSPTPDGSERIGLEVDRRASRSSQSSKE-EVNSEE---YGSD 182
Query: 826 GETESQELSAENHGEAKNDEKGVEDGGGSDGGDSEEEEEEEEEQEEEEEEEEQEEEEEEE 885
ET S S E +N+E+GVE+ D E+ EE+EE E+ EEEEE+EEEEEEE
Sbjct: 183 HETGSSGSSDEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEE 242
Query: 886 EEEEEKGNEE 895
EEEEE+ E+
Sbjct: 243 EEEEEEEYEQ 252
Score = 70.9 bits (172), Expect = 6e-12
Identities = 74/274 (27%), Positives = 118/274 (43%), Gaps = 70/274 (25%)
Query: 615 SRRPVAKVMALEDLSKPGDGAIAVDELQDNKKLKLPSLLTRGSSSTSLHNSTIRSTIYQL 674
++R V + + +SKP +++ +NK++ + T+G S+T N + +
Sbjct: 57 TKRQKPSVHSRQLVSKPLSSSVS-----NNKRI----VSTKGKSATEYKNEEYQRSERN- 106
Query: 675 MLHSLDPLREVRLAKEKEEESLNQGARAQPQAKAESKPEEEEPAKLPAVTVTPAPVPDIK 734
LD R++RL+ E QP+ K + E AK P TP
Sbjct: 107 --KRLDADRKIRLSSSASREPYKN----QPEKTCVRKRDPERRAKSP----TP------- 149
Query: 735 GDQKENPGGQEDVAEAESTGEMPGEEGETAGEGETEEKSGGETQPEGEGETETQGKGEEC 794
D E G + D + S+ +++ E E+ G + + G ++ QG E
Sbjct: 150 -DGSERIGLEVDRRASRSS--------QSSKEEVNSEEYGSDHETGSSGSSDEQGNNTE- 199
Query: 795 EDENEAEGKGDNEGEDEGEIHAEDGEMKGNEGETESQELSAENHGEAKNDEKGVEDGGGS 854
NE EG ++ EDE E +A+ DE+ EDG
Sbjct: 200 ---NEEEGVEEDVEEDE------------------------EVEEDAEEDEEVDEDG--- 229
Query: 855 DGGDSEEEEEEEEEQEEEEEEEEQEEEEEEEEEE 888
+ EEEEEEEEE+EEEEEEEE E++E +++EE
Sbjct: 230 ---EEEEEEEEEEEEEEEEEEEEYEQDERDQKEE 260
Score = 57.4 bits (137), Expect = 7e-08
Identities = 40/128 (31%), Positives = 59/128 (46%), Gaps = 15/128 (11%)
Query: 794 CEDENEAEGKGDNEGEDEGE-IHAEDGEMKGNEGETESQELSAENHGEAKNDEKGVEDGG 852
C + + E + + D E I E ++ +E+++E +G + E G
Sbjct: 134 CVRKRDPERRAKSPTPDGSERIGLEVDRRASRSSQSSKEEVNSEEYGS--DHETGSSGSS 191
Query: 853 GSDGGDSEEEEEEEEEQEEEEEE------------EEQEEEEEEEEEEEEKGNEEPLSLD 900
G ++E EEE EE EE+EE E+ EEEEEEEEEEEE+ EE +
Sbjct: 192 DEQGNNTENEEEGVEEDVEEDEEVEEDAEEDEEVDEDGEEEEEEEEEEEEEEEEEEEEYE 251
Query: 901 WPETRQKQ 908
E QK+
Sbjct: 252 QDERDQKE 259
Score = 41.6 bits (96), Expect = 0.004
Identities = 49/238 (20%), Positives = 89/238 (37%), Gaps = 23/238 (9%)
Query: 641 LQDNKKLKLPSLLTRGSSSTSLHNSTIRSTIYQLMLHSLDPLREVRLAKEKEEESLNQGA 700
L ++K++L S +R + +R + S P R+ E + +
Sbjct: 109 LDADRKIRLSSSASREPYKNQPEKTCVRKRDPERRAKSPTPDGSERIGLEVDRRASRSSQ 168
Query: 701 RAQPQAKAESKPEEEEPAKLPAVTVTPAPVPDIKGDQKENP--GGQEDVAEAESTGEMPG 758
++ + +E + E + D +G+ EN G +EDV E E E
Sbjct: 169 SSKEEVNSEEYGSDHETGSSGS--------SDEQGNNTENEEEGVEEDVEEDEEVEEDAE 220
Query: 759 EEGETAGEG-------ETEEKSGGETQPEGEGETETQGKGEECEDENEAEGKGDNEGEDE 811
E+ E +G E EE+ + E E E Q + ++ E+ N+ + + +
Sbjct: 221 EDEEVDEDGEEEEEEEEEEEE-----EEEEEEEEYEQDERDQKEEGNDYDTRSEASDSGS 275
Query: 812 GEIHAEDGEMKGNEGETESQELSAENHGEAKNDEKGVEDGGGSDGGDSEEEEEEEEEQ 869
+ DG ++ G S E E A+ V D GS +S E++ E+
Sbjct: 276 ESVSFTDGSVRSGSGTDGSDEKKKERK-RARGISPIVFDRSGSSASESYAGSEKKHEK 332
>gi|60498973 myelin transcription factor 1-like [Homo sapiens]
Length = 1184
Score = 71.2 bits (173), Expect = 5e-12
Identities = 43/137 (31%), Positives = 72/137 (52%), Gaps = 22/137 (16%)
Query: 764 AGEGETEEKSGGETQPEGE--GETETQGKGEECEDENEAEGKGDNEGEDEGEIHAEDGEM 821
A + +T++K E P+ + +EC+D + E + E EDEGE ++ED +
Sbjct: 58 AKKRKTQDKQPQEPAPKRKPFAVKADSSSVDECDDSDGTEDMDEKE-EDEGEEYSEDNDE 116
Query: 822 KGNEGETESQELSAENHGEAKNDEKGVEDGGGSDGGDSEEEEEEEEEQEEEEEEEEQEEE 881
G+E E + E+G + + EEE+E+++E E+ E+EE+EEE
Sbjct: 117 PGDEDEED-------------------EEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEE 157
Query: 882 EEEEEEEEEKGNEEPLS 898
EEEEEEEEE+ + ++
Sbjct: 158 EEEEEEEEEENEDHQMN 174
Score = 55.8 bits (133), Expect = 2e-07
Identities = 51/208 (24%), Positives = 86/208 (41%), Gaps = 22/208 (10%)
Query: 702 AQPQAKAESKPEEEEPAKLP-AVTVTPAPVPDIKGDQKENPGGQEDVAEAEST------- 753
A+ + + +P+E P + P AV + V D+ ++ G ED+ E E
Sbjct: 58 AKKRKTQDKQPQEPAPKRKPFAVKADSSSV-----DECDDSDGTEDMDEKEEDEGEEYSE 112
Query: 754 -GEMPGEEGETAGEGETEEKSGGETQPEGEGETETQGKGEECEDENEAEGKGDNEGEDEG 812
+ PG+E E EG+ EE+ E + E + E GE+ EDE E E + E E+E
Sbjct: 113 DNDEPGDEDEEDEEGDREEEEEIEEEDEDDDE-----DGEDVEDEEEEE---EEEEEEEE 164
Query: 813 EIHAEDGEMKGNEGETESQELSAENHGEAKNDEKGVEDGGGSDGGDSEEEEEEEEEQEEE 872
E ED +M + +N+ + ++ + + G E+ E E
Sbjct: 165 EEENEDHQMNCHNTRIMQDTEKDDNNNDEYDNYDELVAKSLLNLGKIAEDAAYRARTESE 224
Query: 873 EEEEEQEEEEEEEEEEEEKGNEEPLSLD 900
E++ ++ E G + LSLD
Sbjct: 225 MNSNTSNSLEDDSDKNENLGRKSELSLD 252
>gi|156142199 euchromatic histone-lysine N-methyltransferase 2
isoform b [Homo sapiens]
Length = 1176
Score = 69.7 bits (169), Expect = 1e-11
Identities = 64/222 (28%), Positives = 91/222 (40%), Gaps = 24/222 (10%)
Query: 695 SLNQGARAQPQAKAESKPEEEEPAKLPAVTVTPAPVPDIKG---------DQKENPGGQE 745
S ++G +AK + P + ++ + +P +G +P GQ
Sbjct: 119 SPSKGGSCPSRAKMSMTGAGKSPPSVQSLAMRLLSMPGAQGAAAAGSEPPPATTSPEGQP 178
Query: 746 DVAEAESTGEMPGEEGETAGEGETEEKSGGETQP-EGEGETETQGKGEECEDENEAEGKG 804
V A T PG G+ EK E Q + + GK + G
Sbjct: 179 KVHRARKTMSKPGN-----GQPPVPEKRPPEIQHFRMSDDVHSLGKVTSDLAKRRKLNSG 233
Query: 805 DNEGEDEGEIHAEDGEM---KGNEGETESQELSAENHGEAKNDEKGVEDGGGSDGGD--- 858
E+ G GE+ KG+ G E E + D V++ SD
Sbjct: 234 GGLSEELGSAR-RSGEVTLTKGDPGSLEEWETVVGDDFSLYYDSYSVDERVDSDSKSEVE 292
Query: 859 --SEEEEEEEEEQEEEEEEEEQEEEEEEEEEEEEKGNEEPLS 898
+E+ EEEEE+EEEEEEEE+EEEEEEEEE+EE GN+ S
Sbjct: 293 ALTEQLSEEEEEEEEEEEEEEEEEEEEEEEEDEESGNQSDRS 334
Score = 39.3 bits (90), Expect = 0.021
Identities = 47/208 (22%), Positives = 83/208 (39%), Gaps = 25/208 (12%)
Query: 699 GARAQPQAKAESKPEEEEPAKLPAV-----TVTPA-----PVPDIKGDQKENPGGQEDVA 748
GA+ A +E P P P V T++ PVP+ + + ++ +DV
Sbjct: 156 GAQGAAAAGSEPPPATTSPEGQPKVHRARKTMSKPGNGQPPVPEKRPPEIQHFRMSDDVH 215
Query: 749 E-AESTGEMPGEEGETAGEGETEEKSGGETQPEGEGETETQGKGEECEDENEAEGKGDNE 807
+ T ++ +G G +EE G + GE T T+G E+ G +
Sbjct: 216 SLGKVTSDLAKRRKLNSGGGLSEEL--GSARRSGE-VTLTKGDPGSLEEWETVVGDDFSL 272
Query: 808 GEDEGEIHAEDGEMKGNEGETESQELSAENHGEAKNDEKGVEDGGGSDGGDSEEEEEEEE 867
D + +E E +++LS E E + +E+ + EEEEEEEE
Sbjct: 273 YYDSYSVDERVDSDSKSEVEALTEQLSEEEEEEEEEEEE-----------EEEEEEEEEE 321
Query: 868 EQEEEEEEEEQEEEEEEEEEEEEKGNEE 895
E++EE + + ++K ++
Sbjct: 322 EEDEESGNQSDRSGSSGRRKAKKKWRKD 349
Score = 32.0 bits (71), Expect = 3.3
Identities = 47/207 (22%), Positives = 78/207 (37%), Gaps = 29/207 (14%)
Query: 691 KEEESLNQGARAQPQAKAESKPEEEEPAKLPAVTVTPAPVPDIKGDQKENPGG--QEDVA 748
+ +++++ QP + PE + V D+ +K N GG E++
Sbjct: 182 RARKTMSKPGNGQPPVPEKRPPEIQHFRMSDDVHSLGKVTSDLAKRRKLNSGGGLSEELG 241
Query: 749 EAESTGEM------PG--EEGETA-GEG--------------ETEEKSGGETQPEG---E 782
A +GE+ PG EE ET G+ +++ KS E E E
Sbjct: 242 SARRSGEVTLTKGDPGSLEEWETVVGDDFSLYYDSYSVDERVDSDSKSEVEALTEQLSEE 301
Query: 783 GETETQGKGEECEDENEAEGKGDNEGEDEGEIHAEDGEMKG-NEGETESQELSAENHGEA 841
E E + + EE E+E E E + D E ++ + G K + +S +
Sbjct: 302 EEEEEEEEEEEEEEEEEEEEEEDEESGNQSDRSGSSGRRKAKKKWRKDSPWVKPSRKRRK 361
Query: 842 KNDEKGVEDGGGSDGGDSEEEEEEEEE 868
+ + E G S+ S E E EE
Sbjct: 362 REPPRAKEPRGVSNDTSSLETERGFEE 388
>gi|156142197 euchromatic histone-lysine N-methyltransferase 2
isoform a [Homo sapiens]
Length = 1210
Score = 69.7 bits (169), Expect = 1e-11
Identities = 64/222 (28%), Positives = 91/222 (40%), Gaps = 24/222 (10%)
Query: 695 SLNQGARAQPQAKAESKPEEEEPAKLPAVTVTPAPVPDIKG---------DQKENPGGQE 745
S ++G +AK + P + ++ + +P +G +P GQ
Sbjct: 119 SPSKGGSCPSRAKMSMTGAGKSPPSVQSLAMRLLSMPGAQGAAAAGSEPPPATTSPEGQP 178
Query: 746 DVAEAESTGEMPGEEGETAGEGETEEKSGGETQP-EGEGETETQGKGEECEDENEAEGKG 804
V A T PG G+ EK E Q + + GK + G
Sbjct: 179 KVHRARKTMSKPGN-----GQPPVPEKRPPEIQHFRMSDDVHSLGKVTSDLAKRRKLNSG 233
Query: 805 DNEGEDEGEIHAEDGEM---KGNEGETESQELSAENHGEAKNDEKGVEDGGGSDGGD--- 858
E+ G GE+ KG+ G E E + D V++ SD
Sbjct: 234 GGLSEELGSAR-RSGEVTLTKGDPGSLEEWETVVGDDFSLYYDSYSVDERVDSDSKSEVE 292
Query: 859 --SEEEEEEEEEQEEEEEEEEQEEEEEEEEEEEEKGNEEPLS 898
+E+ EEEEE+EEEEEEEE+EEEEEEEEE+EE GN+ S
Sbjct: 293 ALTEQLSEEEEEEEEEEEEEEEEEEEEEEEEDEESGNQSDRS 334
Score = 39.3 bits (90), Expect = 0.021
Identities = 47/208 (22%), Positives = 83/208 (39%), Gaps = 25/208 (12%)
Query: 699 GARAQPQAKAESKPEEEEPAKLPAV-----TVTPA-----PVPDIKGDQKENPGGQEDVA 748
GA+ A +E P P P V T++ PVP+ + + ++ +DV
Sbjct: 156 GAQGAAAAGSEPPPATTSPEGQPKVHRARKTMSKPGNGQPPVPEKRPPEIQHFRMSDDVH 215
Query: 749 E-AESTGEMPGEEGETAGEGETEEKSGGETQPEGEGETETQGKGEECEDENEAEGKGDNE 807
+ T ++ +G G +EE G + GE T T+G E+ G +
Sbjct: 216 SLGKVTSDLAKRRKLNSGGGLSEEL--GSARRSGE-VTLTKGDPGSLEEWETVVGDDFSL 272
Query: 808 GEDEGEIHAEDGEMKGNEGETESQELSAENHGEAKNDEKGVEDGGGSDGGDSEEEEEEEE 867
D + +E E +++LS E E + +E+ + EEEEEEEE
Sbjct: 273 YYDSYSVDERVDSDSKSEVEALTEQLSEEEEEEEEEEEE-----------EEEEEEEEEE 321
Query: 868 EQEEEEEEEEQEEEEEEEEEEEEKGNEE 895
E++EE + + ++K ++
Sbjct: 322 EEDEESGNQSDRSGSSGRRKAKKKWRKD 349
Score = 30.8 bits (68), Expect = 7.4
Identities = 44/205 (21%), Positives = 76/205 (37%), Gaps = 28/205 (13%)
Query: 691 KEEESLNQGARAQPQAKAESKPEEEEPAKLPAVTVTPAPVPDIKGDQKENPGG--QEDVA 748
+ +++++ QP + PE + V D+ +K N GG E++
Sbjct: 182 RARKTMSKPGNGQPPVPEKRPPEIQHFRMSDDVHSLGKVTSDLAKRRKLNSGGGLSEELG 241
Query: 749 EAESTGEM------PG--EEGETA-GEG--------------ETEEKSGGETQPEG---E 782
A +GE+ PG EE ET G+ +++ KS E E E
Sbjct: 242 SARRSGEVTLTKGDPGSLEEWETVVGDDFSLYYDSYSVDERVDSDSKSEVEALTEQLSEE 301
Query: 783 GETETQGKGEECEDENEAEGKGDNEGEDEGEIHAEDGEMKGNEGETESQELSAENHGEAK 842
E E + + EE E+E E E + D E ++ + G K + + + K
Sbjct: 302 EEEEEEEEEEEEEEEEEEEEEEDEESGNQSDRSGSSGRRKAKKKWRKDSPWVKPSRKRRK 361
Query: 843 NDEKGVEDGGGSDGGDSEEEEEEEE 867
+ ++ G +G S E E
Sbjct: 362 REPPRAKEPRGVNGVGSSGPSEYME 386
>gi|61676188 HECT, UBA and WWE domain containing 1 [Homo sapiens]
Length = 4374
Score = 69.7 bits (169), Expect = 1e-11
Identities = 55/222 (24%), Positives = 98/222 (44%), Gaps = 39/222 (17%)
Query: 720 LPAVTVTPAPVPDIKGDQKENPGGQEDVAEAESTGEMPGEEGETAGEGETEEKSGGETQP 779
L + P+ + K +N Q+ ++ + + GE GE E +E+ TQ
Sbjct: 2253 LSRIVNQPSSLFGSKSASSKNKSEQDAQGASQDSSSNQQDPGEP-GEAEVQEEDHDVTQT 2311
Query: 780 EG------EGETETQG----------KGEECEDENEAE-----------GKGDN------ 806
E +GE ET +E + ENE E G G++
Sbjct: 2312 EVADGDIMDGEAETDSVVIAGQPEVLSSQEMQVENELEDLIDELLERDGGSGNSTIIVSR 2371
Query: 807 EGEDEGEIHAEDGEMKGNEGETESQELSAENH-----GEAKNDEKGVEDGGGSDGGDSEE 861
GEDE + E N + + + + E+ E + + ED GS+ + +
Sbjct: 2372 SGEDESQEDVLMDEAPSNLSQASTLQANREDSMNILDPEDEEEHTQEEDSSGSNEDEDDS 2431
Query: 862 EEEEEEEQEEEEEEEEQEEEEEEEEEEEEKGNEEPLSLDWPE 903
++EEEEE+E+EE+++E +E EE +E++++ G+E L D+P+
Sbjct: 2432 QDEEEEEEEDEEDDQEDDEGEEGDEDDDDDGSEMELDEDYPD 2473
Score = 43.9 bits (102), Expect = 8e-04
Identities = 41/173 (23%), Positives = 63/173 (36%), Gaps = 31/173 (17%)
Query: 760 EGETAGEGETEEKSGGETQPEGEGETETQGKGEECEDENEAEGK-GDNEGEDEGEIHAED 818
+ E +G +++ S + P GE E Q + + A+G D E E + + A
Sbjct: 2274 KSEQDAQGASQDSSSNQQDPGEPGEAEVQEEDHDVTQTEVADGDIMDGEAETDSVVIAGQ 2333
Query: 819 GEMKGNEGETESQELSAENHGEAKNDEKGVEDGGGSDGGDSEEEEEEEEEQEEEEEEE-- 876
E+ SQE+ EN E DE DGG + E+E QE+ +E
Sbjct: 2334 PEV------LSSQEMQVENELEDLIDELLERDGGSGNSTIIVSRSGEDESQEDVLMDEAP 2387
Query: 877 ----------------------EQEEEEEEEEEEEEKGNEEPLSLDWPETRQK 907
E EEE +EE+ +E S D E ++
Sbjct: 2388 SNLSQASTLQANREDSMNILDPEDEEEHTQEEDSSGSNEDEDDSQDEEEEEEE 2440
Score = 38.9 bits (89), Expect = 0.027
Identities = 48/229 (20%), Positives = 82/229 (35%), Gaps = 21/229 (9%)
Query: 684 EVRLAKEKEEESLNQGARAQPQAKAESKPEEE---EPAKLP-AVTVTPAPVPDIKGDQKE 739
E ++ + +E+ N+ AQ A + E+ + +P + TP+ + KE
Sbjct: 2701 ETKITDKGKEDKENRDQSAQCTASKSNDSTEQNLSDGTPMPDSYPTTPSSTDAATSESKE 2760
Query: 740 NPGG------QEDVAEAESTGEMPGEEGETAGEGETEEKSGGETQPEGEGETETQGKGE- 792
G Q + + GE+P E AGEG + + +PE G T G+ E
Sbjct: 2761 TLGTLQSSQQQPTLPTPPALGEVPQELQSPAGEGGSSTQLLMPVEPEELGPTRPSGEAET 2820
Query: 793 ---ECEDENEAEGKGDNEGEDEGEIHAEDGEMKGNEGETESQELSAENHGEAKNDEKGVE 849
E ED + A +++G+ +T S L++ EA D
Sbjct: 2821 TQMELSPAPTITSLSPERAEDSDALTAVSSQLEGSPMDTSS--LASCTLEEAVGDTSAAG 2878
Query: 850 D-----GGGSDGGDSEEEEEEEEEQEEEEEEEEQEEEEEEEEEEEEKGN 893
G S GD+ E + + + E Q E+ E +
Sbjct: 2879 SSEQPRAGSSTPGDAPPAVAEVQGRSDGSGESAQPPEDSSPPASSESSS 2927
Score = 35.8 bits (81), Expect = 0.23
Identities = 30/128 (23%), Positives = 54/128 (42%), Gaps = 16/128 (12%)
Query: 764 AGEGETEEKSGGETQPEGEGETET-QGKGEEC------EDENEAEGKGDNEGEDEGEIHA 816
+GE E++E + P + T Q E+ EDE E + D+ G +E E +
Sbjct: 2372 SGEDESQEDVLMDEAPSNLSQASTLQANREDSMNILDPEDEEEHTQEEDSSGSNEDEDDS 2431
Query: 817 EDGEMKGNEGETESQELSAENHGEAKNDEKGVEDGGGSDGGDSEEEEEEEEEQEEEEEEE 876
+D E + E E + QE G+ +D+ DG + E +E+ +
Sbjct: 2432 QDEEEEEEEDEEDDQEDDEGEEGDEDDDD---------DGSEMELDEDYPDMNASPLVRF 2482
Query: 877 EQEEEEEE 884
E+ + E++
Sbjct: 2483 ERFDREDD 2490
Score = 33.1 bits (74), Expect = 1.5
Identities = 29/96 (30%), Positives = 44/96 (45%), Gaps = 5/96 (5%)
Query: 319 SEGQVTISTMTGSSPAETKAFTAAWSLRNPSPRTSVSAIKTAPAIVWRLAKKP--STAPS 376
+ G ST T +S T TAA + P+P T+ + + +APA+V A A +
Sbjct: 3475 NSGSGASSTTTATSTTSTTTTTAAST--TPTPPTAPTPVTSAPALVAATAISTIVVAAST 3532
Query: 377 TSTTPTVRAKLTMQVHHCVVVKPTPAMLTTPSPSLT 412
T TTPT A T+ + +PA ++ S T
Sbjct: 3533 TVTTPTT-ATTTVSISPTTKGSKSPAKVSDGGSSST 3567
Score = 30.4 bits (67), Expect = 9.6
Identities = 17/45 (37%), Positives = 25/45 (55%), Gaps = 2/45 (4%)
Query: 858 DSEEEEEEEEEQEEEEEEEEQEEEEEEEEEE--EEKGNEEPLSLD 900
D E EE +EEEE + E++EEEE + E+ + +PL D
Sbjct: 1390 DQRAESPEEVACRKEEEERKAREKQEEEEAKCLEKFQDADPLEQD 1434
>gi|116284392 mucin 2 precursor [Homo sapiens]
Length = 5179
Score = 68.6 bits (166), Expect = 3e-11
Identities = 85/347 (24%), Positives = 126/347 (36%), Gaps = 44/347 (12%)
Query: 103 TLSMTVENIPSMPKRTAKMIPTTTKNNYSPTAAGTERRKED----------TPTSSRTLT 152
T++ T P+ P T I TTT +PT GT+ TPT + T T
Sbjct: 1884 TMTTTTTENPTPPTTTP--ITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQT 1941
Query: 153 YYTSTSSRQIVKKYTPTPRG-EMKSYSPTQVREKVKYTPSPRGRRVGTYVPSTFMTMETS 211
T+ + TPTP G + + +P V TP+P G + T P T T+
Sbjct: 1942 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT-----TT 1996
Query: 212 HAITPRTTVKDSDITATYKILETNSLKRIMEETTPTTLKGMFDSTPTFLTHEVEANVLTS 271
+TP T + T I T + + TPT + TPT V +
Sbjct: 1997 TTVTPTPTPTGTQTPTTTPITTTTT---VTPTPTPTGTQ-----TPTTTPITTTTTVTPT 2048
Query: 272 PRSVMEKNNLFPPRRVESNSSAHPWGLVGKSNPKTPQGTVL-LHTPATSEGQVTIS-TMT 329
P + P + + P TP GT TP T+ VT + T T
Sbjct: 2049 PTPTGTQTPTTTPITTTTTVTPTP----------TPTGTQTPTTTPITTTTTVTPTPTPT 2098
Query: 330 GSSPAETKAFTAAWSLRNPSPRTSVSAIKTAPAIVWRLAKKPSTAPSTSTTPTVRAKLTM 389
G+ T T ++ P+P + + T I P+ P+ + TPT T
Sbjct: 2099 GTQTPTTTPITTTTTV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT-----TT 2152
Query: 390 QVHHCVVVKPTPAMLTTPSPSLTTALLPEELSPSPSVLPPSLPDLHP 436
+ V PTP T +P+ T ++P+P+ P P
Sbjct: 2153 PITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2199
Score = 68.6 bits (166), Expect = 3e-11
Identities = 83/319 (26%), Positives = 117/319 (36%), Gaps = 41/319 (12%)
Query: 107 TVENIPSMPKRTAKMIPTTTKNNYSPTAAGTERRKEDTPTSSRTLTYYTSTSSRQIVKKY 166
T + P T PTTT + T T TPT ++T T T++ +
Sbjct: 4042 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-----TPTGTQTPTTTPITTTTTVTP-- 4094
Query: 167 TPTPRG-EMKSYSPTQVREKVKYTPSPRGRRVGTYVPSTFMTMETSHAITPRTTVKDSDI 225
TPTP G + + +P V TP+P G + T P T T+ +TP T +
Sbjct: 4095 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPTGTQT 4149
Query: 226 TATYKILETNSLKRI-------MEETTPTTLKGMFDSTPTFLTHEVEANVLTSPRSVMEK 278
T I T ++ TTP T TPT + TS + E
Sbjct: 4150 PTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTGPPTHTSTAPIAEL 4209
Query: 279 NNLFPPRRVESNSSAHPWGLVGKSNPKTPQGTVLLHTPATSEGQVTISTMTGSSPAETKA 338
PP S+ P S+P T T+L P E T T ++P T
Sbjct: 4210 TTSNPPPE-----SSTPQTSRSTSSPLTESTTLLSTLPPAIEMTSTAPPSTPTAPTTT-- 4262
Query: 339 FTAAWSLRNPSPRTSVSAIKTAPAIVWRLAKKPSTAPSTSTTPTVRAKLTMQVHHCVVVK 398
+ +P P T+ S T + +T S++ TP+ T+Q
Sbjct: 4263 --SGGHTLSPPPSTTTSPPGTP-------TRGTTTGSSSAPTPS-----TVQTTTTSAWT 4308
Query: 399 PTPAMLTTPSPSLTTALLP 417
PTP L+TPS TT L P
Sbjct: 4309 PTPTPLSTPSIIRTTGLRP 4327
Score = 68.2 bits (165), Expect = 4e-11
Identities = 81/333 (24%), Positives = 121/333 (36%), Gaps = 39/333 (11%)
Query: 107 TVENIPSMPKRTAKMIPTTTKNNYSPTAAGTERRKEDTPTSSRTLTYYTSTSSRQIVKKY 166
T + P T PTTT + T T TPT ++T T T++ +
Sbjct: 1926 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-----TPTGTQTPTTTPITTTTTVTP-- 1978
Query: 167 TPTPRG-EMKSYSPTQVREKVKYTPSPRGRRVGTYVPSTFMTMETSHAITPRTTVKDSDI 225
TPTP G + + +P V TP+P G + T P T T+ +TP T +
Sbjct: 1979 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPTGTQT 2033
Query: 226 TATYKILETNSLKRIMEETTPTTLKGMFDSTPTFLTHEVEANVLTSPRSVMEKNNLFPPR 285
T I T + + TPT + TPT V +P + P
Sbjct: 2034 PTTTPITTTTT---VTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2085
Query: 286 RVESNSSAHPWGLVGKSNPKTPQGTVL-LHTPATSEGQVTIS-TMTGSSPAETKAFTAAW 343
+ + P TP GT TP T+ VT + T TG+ T T
Sbjct: 2086 TTTTTVTPTP----------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2135
Query: 344 SLRNPSPRTSVSAIKTAPAIVWRLAKKPSTAPSTSTTPTVRAKLTMQVHHCVVVKPTPAM 403
++ P+P + + T I P+ P+ + TPT T + V PTP
Sbjct: 2136 TV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT-----TTPITTTTTVTPTPTP 2189
Query: 404 LTTPSPSLTTALLPEELSPSPSVLPPSLPDLHP 436
T +P+ T ++P+P+ P P
Sbjct: 2190 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2222
Score = 68.2 bits (165), Expect = 4e-11
Identities = 81/333 (24%), Positives = 121/333 (36%), Gaps = 39/333 (11%)
Query: 107 TVENIPSMPKRTAKMIPTTTKNNYSPTAAGTERRKEDTPTSSRTLTYYTSTSSRQIVKKY 166
T + P T PTTT + T T TPT ++T T T++ +
Sbjct: 1949 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-----TPTGTQTPTTTPITTTTTVTP-- 2001
Query: 167 TPTPRG-EMKSYSPTQVREKVKYTPSPRGRRVGTYVPSTFMTMETSHAITPRTTVKDSDI 225
TPTP G + + +P V TP+P G + T P T T+ +TP T +
Sbjct: 2002 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPTGTQT 2056
Query: 226 TATYKILETNSLKRIMEETTPTTLKGMFDSTPTFLTHEVEANVLTSPRSVMEKNNLFPPR 285
T I T + + TPT + TPT V +P + P
Sbjct: 2057 PTTTPITTTTT---VTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2108
Query: 286 RVESNSSAHPWGLVGKSNPKTPQGTVL-LHTPATSEGQVTIS-TMTGSSPAETKAFTAAW 343
+ + P TP GT TP T+ VT + T TG+ T T
Sbjct: 2109 TTTTTVTPTP----------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2158
Query: 344 SLRNPSPRTSVSAIKTAPAIVWRLAKKPSTAPSTSTTPTVRAKLTMQVHHCVVVKPTPAM 403
++ P+P + + T I P+ P+ + TPT T + V PTP
Sbjct: 2159 TV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT-----TTPITTTTTVTPTPTP 2212
Query: 404 LTTPSPSLTTALLPEELSPSPSVLPPSLPDLHP 436
T +P+ T ++P+P+ P P
Sbjct: 2213 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2245
Score = 68.2 bits (165), Expect = 4e-11
Identities = 81/333 (24%), Positives = 121/333 (36%), Gaps = 39/333 (11%)
Query: 107 TVENIPSMPKRTAKMIPTTTKNNYSPTAAGTERRKEDTPTSSRTLTYYTSTSSRQIVKKY 166
T + P T PTTT + T T TPT ++T T T++ +
Sbjct: 1972 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-----TPTGTQTPTTTPITTTTTVTP-- 2024
Query: 167 TPTPRG-EMKSYSPTQVREKVKYTPSPRGRRVGTYVPSTFMTMETSHAITPRTTVKDSDI 225
TPTP G + + +P V TP+P G + T P T T+ +TP T +
Sbjct: 2025 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPTGTQT 2079
Query: 226 TATYKILETNSLKRIMEETTPTTLKGMFDSTPTFLTHEVEANVLTSPRSVMEKNNLFPPR 285
T I T + + TPT + TPT V +P + P
Sbjct: 2080 PTTTPITTTTT---VTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2131
Query: 286 RVESNSSAHPWGLVGKSNPKTPQGTVL-LHTPATSEGQVTIS-TMTGSSPAETKAFTAAW 343
+ + P TP GT TP T+ VT + T TG+ T T
Sbjct: 2132 TTTTTVTPTP----------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2181
Query: 344 SLRNPSPRTSVSAIKTAPAIVWRLAKKPSTAPSTSTTPTVRAKLTMQVHHCVVVKPTPAM 403
++ P+P + + T I P+ P+ + TPT T + V PTP
Sbjct: 2182 TV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT-----TTPITTTTTVTPTPTP 2235
Query: 404 LTTPSPSLTTALLPEELSPSPSVLPPSLPDLHP 436
T +P+ T ++P+P+ P P
Sbjct: 2236 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2268
Score = 68.2 bits (165), Expect = 4e-11
Identities = 81/333 (24%), Positives = 121/333 (36%), Gaps = 39/333 (11%)
Query: 107 TVENIPSMPKRTAKMIPTTTKNNYSPTAAGTERRKEDTPTSSRTLTYYTSTSSRQIVKKY 166
T + P T PTTT + T T TPT ++T T T++ +
Sbjct: 1995 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-----TPTGTQTPTTTPITTTTTVTP-- 2047
Query: 167 TPTPRG-EMKSYSPTQVREKVKYTPSPRGRRVGTYVPSTFMTMETSHAITPRTTVKDSDI 225
TPTP G + + +P V TP+P G + T P T T+ +TP T +
Sbjct: 2048 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPTGTQT 2102
Query: 226 TATYKILETNSLKRIMEETTPTTLKGMFDSTPTFLTHEVEANVLTSPRSVMEKNNLFPPR 285
T I T + + TPT + TPT V +P + P
Sbjct: 2103 PTTTPITTTTT---VTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2154
Query: 286 RVESNSSAHPWGLVGKSNPKTPQGTVL-LHTPATSEGQVTIS-TMTGSSPAETKAFTAAW 343
+ + P TP GT TP T+ VT + T TG+ T T
Sbjct: 2155 TTTTTVTPTP----------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2204
Query: 344 SLRNPSPRTSVSAIKTAPAIVWRLAKKPSTAPSTSTTPTVRAKLTMQVHHCVVVKPTPAM 403
++ P+P + + T I P+ P+ + TPT T + V PTP
Sbjct: 2205 TV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT-----TTPITTTTTVTPTPTP 2258
Query: 404 LTTPSPSLTTALLPEELSPSPSVLPPSLPDLHP 436
T +P+ T ++P+P+ P P
Sbjct: 2259 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2291
Score = 68.2 bits (165), Expect = 4e-11
Identities = 81/333 (24%), Positives = 121/333 (36%), Gaps = 39/333 (11%)
Query: 107 TVENIPSMPKRTAKMIPTTTKNNYSPTAAGTERRKEDTPTSSRTLTYYTSTSSRQIVKKY 166
T + P T PTTT + T T TPT ++T T T++ +
Sbjct: 2018 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-----TPTGTQTPTTTPITTTTTVTP-- 2070
Query: 167 TPTPRG-EMKSYSPTQVREKVKYTPSPRGRRVGTYVPSTFMTMETSHAITPRTTVKDSDI 225
TPTP G + + +P V TP+P G + T P T T+ +TP T +
Sbjct: 2071 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPTGTQT 2125
Query: 226 TATYKILETNSLKRIMEETTPTTLKGMFDSTPTFLTHEVEANVLTSPRSVMEKNNLFPPR 285
T I T + + TPT + TPT V +P + P
Sbjct: 2126 PTTTPITTTTT---VTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2177
Query: 286 RVESNSSAHPWGLVGKSNPKTPQGTVL-LHTPATSEGQVTIS-TMTGSSPAETKAFTAAW 343
+ + P TP GT TP T+ VT + T TG+ T T
Sbjct: 2178 TTTTTVTPTP----------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2227
Query: 344 SLRNPSPRTSVSAIKTAPAIVWRLAKKPSTAPSTSTTPTVRAKLTMQVHHCVVVKPTPAM 403
++ P+P + + T I P+ P+ + TPT T + V PTP
Sbjct: 2228 TV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT-----TTPITTTTTVTPTPTP 2281
Query: 404 LTTPSPSLTTALLPEELSPSPSVLPPSLPDLHP 436
T +P+ T ++P+P+ P P
Sbjct: 2282 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2314
Score = 68.2 bits (165), Expect = 4e-11
Identities = 81/333 (24%), Positives = 121/333 (36%), Gaps = 39/333 (11%)
Query: 107 TVENIPSMPKRTAKMIPTTTKNNYSPTAAGTERRKEDTPTSSRTLTYYTSTSSRQIVKKY 166
T + P T PTTT + T T TPT ++T T T++ +
Sbjct: 2041 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-----TPTGTQTPTTTPITTTTTVTP-- 2093
Query: 167 TPTPRG-EMKSYSPTQVREKVKYTPSPRGRRVGTYVPSTFMTMETSHAITPRTTVKDSDI 225
TPTP G + + +P V TP+P G + T P T T+ +TP T +
Sbjct: 2094 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPTGTQT 2148
Query: 226 TATYKILETNSLKRIMEETTPTTLKGMFDSTPTFLTHEVEANVLTSPRSVMEKNNLFPPR 285
T I T + + TPT + TPT V +P + P
Sbjct: 2149 PTTTPITTTTT---VTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2200
Query: 286 RVESNSSAHPWGLVGKSNPKTPQGTVL-LHTPATSEGQVTIS-TMTGSSPAETKAFTAAW 343
+ + P TP GT TP T+ VT + T TG+ T T
Sbjct: 2201 TTTTTVTPTP----------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2250
Query: 344 SLRNPSPRTSVSAIKTAPAIVWRLAKKPSTAPSTSTTPTVRAKLTMQVHHCVVVKPTPAM 403
++ P+P + + T I P+ P+ + TPT T + V PTP
Sbjct: 2251 TV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT-----TTPITTTTTVTPTPTP 2304
Query: 404 LTTPSPSLTTALLPEELSPSPSVLPPSLPDLHP 436
T +P+ T ++P+P+ P P
Sbjct: 2305 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2337
Score = 68.2 bits (165), Expect = 4e-11
Identities = 81/333 (24%), Positives = 121/333 (36%), Gaps = 39/333 (11%)
Query: 107 TVENIPSMPKRTAKMIPTTTKNNYSPTAAGTERRKEDTPTSSRTLTYYTSTSSRQIVKKY 166
T + P T PTTT + T T TPT ++T T T++ +
Sbjct: 2064 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-----TPTGTQTPTTTPITTTTTVTP-- 2116
Query: 167 TPTPRG-EMKSYSPTQVREKVKYTPSPRGRRVGTYVPSTFMTMETSHAITPRTTVKDSDI 225
TPTP G + + +P V TP+P G + T P T T+ +TP T +
Sbjct: 2117 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPTGTQT 2171
Query: 226 TATYKILETNSLKRIMEETTPTTLKGMFDSTPTFLTHEVEANVLTSPRSVMEKNNLFPPR 285
T I T + + TPT + TPT V +P + P
Sbjct: 2172 PTTTPITTTTT---VTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2223
Query: 286 RVESNSSAHPWGLVGKSNPKTPQGTVL-LHTPATSEGQVTIS-TMTGSSPAETKAFTAAW 343
+ + P TP GT TP T+ VT + T TG+ T T
Sbjct: 2224 TTTTTVTPTP----------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2273
Query: 344 SLRNPSPRTSVSAIKTAPAIVWRLAKKPSTAPSTSTTPTVRAKLTMQVHHCVVVKPTPAM 403
++ P+P + + T I P+ P+ + TPT T + V PTP
Sbjct: 2274 TV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT-----TTPITTTTTVTPTPTP 2327
Query: 404 LTTPSPSLTTALLPEELSPSPSVLPPSLPDLHP 436
T +P+ T ++P+P+ P P
Sbjct: 2328 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2360
Score = 68.2 bits (165), Expect = 4e-11
Identities = 81/333 (24%), Positives = 121/333 (36%), Gaps = 39/333 (11%)
Query: 107 TVENIPSMPKRTAKMIPTTTKNNYSPTAAGTERRKEDTPTSSRTLTYYTSTSSRQIVKKY 166
T + P T PTTT + T T TPT ++T T T++ +
Sbjct: 2087 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-----TPTGTQTPTTTPITTTTTVTP-- 2139
Query: 167 TPTPRG-EMKSYSPTQVREKVKYTPSPRGRRVGTYVPSTFMTMETSHAITPRTTVKDSDI 225
TPTP G + + +P V TP+P G + T P T T+ +TP T +
Sbjct: 2140 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPTGTQT 2194
Query: 226 TATYKILETNSLKRIMEETTPTTLKGMFDSTPTFLTHEVEANVLTSPRSVMEKNNLFPPR 285
T I T + + TPT + TPT V +P + P
Sbjct: 2195 PTTTPITTTTT---VTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2246
Query: 286 RVESNSSAHPWGLVGKSNPKTPQGTVL-LHTPATSEGQVTIS-TMTGSSPAETKAFTAAW 343
+ + P TP GT TP T+ VT + T TG+ T T
Sbjct: 2247 TTTTTVTPTP----------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2296
Query: 344 SLRNPSPRTSVSAIKTAPAIVWRLAKKPSTAPSTSTTPTVRAKLTMQVHHCVVVKPTPAM 403
++ P+P + + T I P+ P+ + TPT T + V PTP
Sbjct: 2297 TV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT-----TTPITTTTTVTPTPTP 2350
Query: 404 LTTPSPSLTTALLPEELSPSPSVLPPSLPDLHP 436
T +P+ T ++P+P+ P P
Sbjct: 2351 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2383
Score = 68.2 bits (165), Expect = 4e-11
Identities = 81/333 (24%), Positives = 121/333 (36%), Gaps = 39/333 (11%)
Query: 107 TVENIPSMPKRTAKMIPTTTKNNYSPTAAGTERRKEDTPTSSRTLTYYTSTSSRQIVKKY 166
T + P T PTTT + T T TPT ++T T T++ +
Sbjct: 2110 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-----TPTGTQTPTTTPITTTTTVTP-- 2162
Query: 167 TPTPRG-EMKSYSPTQVREKVKYTPSPRGRRVGTYVPSTFMTMETSHAITPRTTVKDSDI 225
TPTP G + + +P V TP+P G + T P T T+ +TP T +
Sbjct: 2163 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPTGTQT 2217
Query: 226 TATYKILETNSLKRIMEETTPTTLKGMFDSTPTFLTHEVEANVLTSPRSVMEKNNLFPPR 285
T I T + + TPT + TPT V +P + P
Sbjct: 2218 PTTTPITTTTT---VTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2269
Query: 286 RVESNSSAHPWGLVGKSNPKTPQGTVL-LHTPATSEGQVTIS-TMTGSSPAETKAFTAAW 343
+ + P TP GT TP T+ VT + T TG+ T T
Sbjct: 2270 TTTTTVTPTP----------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2319
Query: 344 SLRNPSPRTSVSAIKTAPAIVWRLAKKPSTAPSTSTTPTVRAKLTMQVHHCVVVKPTPAM 403
++ P+P + + T I P+ P+ + TPT T + V PTP
Sbjct: 2320 TV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT-----TTPITTTTTVTPTPTP 2373
Query: 404 LTTPSPSLTTALLPEELSPSPSVLPPSLPDLHP 436
T +P+ T ++P+P+ P P
Sbjct: 2374 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2406
Score = 68.2 bits (165), Expect = 4e-11
Identities = 81/333 (24%), Positives = 121/333 (36%), Gaps = 39/333 (11%)
Query: 107 TVENIPSMPKRTAKMIPTTTKNNYSPTAAGTERRKEDTPTSSRTLTYYTSTSSRQIVKKY 166
T + P T PTTT + T T TPT ++T T T++ +
Sbjct: 2133 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-----TPTGTQTPTTTPITTTTTVTP-- 2185
Query: 167 TPTPRG-EMKSYSPTQVREKVKYTPSPRGRRVGTYVPSTFMTMETSHAITPRTTVKDSDI 225
TPTP G + + +P V TP+P G + T P T T+ +TP T +
Sbjct: 2186 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPTGTQT 2240
Query: 226 TATYKILETNSLKRIMEETTPTTLKGMFDSTPTFLTHEVEANVLTSPRSVMEKNNLFPPR 285
T I T + + TPT + TPT V +P + P
Sbjct: 2241 PTTTPITTTTT---VTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2292
Query: 286 RVESNSSAHPWGLVGKSNPKTPQGTVL-LHTPATSEGQVTIS-TMTGSSPAETKAFTAAW 343
+ + P TP GT TP T+ VT + T TG+ T T
Sbjct: 2293 TTTTTVTPTP----------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2342
Query: 344 SLRNPSPRTSVSAIKTAPAIVWRLAKKPSTAPSTSTTPTVRAKLTMQVHHCVVVKPTPAM 403
++ P+P + + T I P+ P+ + TPT T + V PTP
Sbjct: 2343 TV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT-----TTPITTTTTVTPTPTP 2396
Query: 404 LTTPSPSLTTALLPEELSPSPSVLPPSLPDLHP 436
T +P+ T ++P+P+ P P
Sbjct: 2397 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2429
Score = 68.2 bits (165), Expect = 4e-11
Identities = 81/333 (24%), Positives = 121/333 (36%), Gaps = 39/333 (11%)
Query: 107 TVENIPSMPKRTAKMIPTTTKNNYSPTAAGTERRKEDTPTSSRTLTYYTSTSSRQIVKKY 166
T + P T PTTT + T T TPT ++T T T++ +
Sbjct: 2156 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-----TPTGTQTPTTTPITTTTTVTP-- 2208
Query: 167 TPTPRG-EMKSYSPTQVREKVKYTPSPRGRRVGTYVPSTFMTMETSHAITPRTTVKDSDI 225
TPTP G + + +P V TP+P G + T P T T+ +TP T +
Sbjct: 2209 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPTGTQT 2263
Query: 226 TATYKILETNSLKRIMEETTPTTLKGMFDSTPTFLTHEVEANVLTSPRSVMEKNNLFPPR 285
T I T + + TPT + TPT V +P + P
Sbjct: 2264 PTTTPITTTTT---VTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2315
Query: 286 RVESNSSAHPWGLVGKSNPKTPQGTVL-LHTPATSEGQVTIS-TMTGSSPAETKAFTAAW 343
+ + P TP GT TP T+ VT + T TG+ T T
Sbjct: 2316 TTTTTVTPTP----------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2365
Query: 344 SLRNPSPRTSVSAIKTAPAIVWRLAKKPSTAPSTSTTPTVRAKLTMQVHHCVVVKPTPAM 403
++ P+P + + T I P+ P+ + TPT T + V PTP
Sbjct: 2366 TV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT-----TTPITTTTTVTPTPTP 2419
Query: 404 LTTPSPSLTTALLPEELSPSPSVLPPSLPDLHP 436
T +P+ T ++P+P+ P P
Sbjct: 2420 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2452
Score = 68.2 bits (165), Expect = 4e-11
Identities = 81/333 (24%), Positives = 121/333 (36%), Gaps = 39/333 (11%)
Query: 107 TVENIPSMPKRTAKMIPTTTKNNYSPTAAGTERRKEDTPTSSRTLTYYTSTSSRQIVKKY 166
T + P T PTTT + T T TPT ++T T T++ +
Sbjct: 2179 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-----TPTGTQTPTTTPITTTTTVTP-- 2231
Query: 167 TPTPRG-EMKSYSPTQVREKVKYTPSPRGRRVGTYVPSTFMTMETSHAITPRTTVKDSDI 225
TPTP G + + +P V TP+P G + T P T T+ +TP T +
Sbjct: 2232 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPTGTQT 2286
Query: 226 TATYKILETNSLKRIMEETTPTTLKGMFDSTPTFLTHEVEANVLTSPRSVMEKNNLFPPR 285
T I T + + TPT + TPT V +P + P
Sbjct: 2287 PTTTPITTTTT---VTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2338
Query: 286 RVESNSSAHPWGLVGKSNPKTPQGTVL-LHTPATSEGQVTIS-TMTGSSPAETKAFTAAW 343
+ + P TP GT TP T+ VT + T TG+ T T
Sbjct: 2339 TTTTTVTPTP----------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2388
Query: 344 SLRNPSPRTSVSAIKTAPAIVWRLAKKPSTAPSTSTTPTVRAKLTMQVHHCVVVKPTPAM 403
++ P+P + + T I P+ P+ + TPT T + V PTP
Sbjct: 2389 TV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT-----TTPITTTTTVTPTPTP 2442
Query: 404 LTTPSPSLTTALLPEELSPSPSVLPPSLPDLHP 436
T +P+ T ++P+P+ P P
Sbjct: 2443 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2475
Score = 68.2 bits (165), Expect = 4e-11
Identities = 81/333 (24%), Positives = 121/333 (36%), Gaps = 39/333 (11%)
Query: 107 TVENIPSMPKRTAKMIPTTTKNNYSPTAAGTERRKEDTPTSSRTLTYYTSTSSRQIVKKY 166
T + P T PTTT + T T TPT ++T T T++ +
Sbjct: 2202 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-----TPTGTQTPTTTPITTTTTVTP-- 2254
Query: 167 TPTPRG-EMKSYSPTQVREKVKYTPSPRGRRVGTYVPSTFMTMETSHAITPRTTVKDSDI 225
TPTP G + + +P V TP+P G + T P T T+ +TP T +
Sbjct: 2255 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPTGTQT 2309
Query: 226 TATYKILETNSLKRIMEETTPTTLKGMFDSTPTFLTHEVEANVLTSPRSVMEKNNLFPPR 285
T I T + + TPT + TPT V +P + P
Sbjct: 2310 PTTTPITTTTT---VTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2361
Query: 286 RVESNSSAHPWGLVGKSNPKTPQGTVL-LHTPATSEGQVTIS-TMTGSSPAETKAFTAAW 343
+ + P TP GT TP T+ VT + T TG+ T T
Sbjct: 2362 TTTTTVTPTP----------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2411
Query: 344 SLRNPSPRTSVSAIKTAPAIVWRLAKKPSTAPSTSTTPTVRAKLTMQVHHCVVVKPTPAM 403
++ P+P + + T I P+ P+ + TPT T + V PTP
Sbjct: 2412 TV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT-----TTPITTTTTVTPTPTP 2465
Query: 404 LTTPSPSLTTALLPEELSPSPSVLPPSLPDLHP 436
T +P+ T ++P+P+ P P
Sbjct: 2466 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2498
Score = 68.2 bits (165), Expect = 4e-11
Identities = 81/333 (24%), Positives = 121/333 (36%), Gaps = 39/333 (11%)
Query: 107 TVENIPSMPKRTAKMIPTTTKNNYSPTAAGTERRKEDTPTSSRTLTYYTSTSSRQIVKKY 166
T + P T PTTT + T T TPT ++T T T++ +
Sbjct: 2225 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-----TPTGTQTPTTTPITTTTTVTP-- 2277
Query: 167 TPTPRG-EMKSYSPTQVREKVKYTPSPRGRRVGTYVPSTFMTMETSHAITPRTTVKDSDI 225
TPTP G + + +P V TP+P G + T P T T+ +TP T +
Sbjct: 2278 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPTGTQT 2332
Query: 226 TATYKILETNSLKRIMEETTPTTLKGMFDSTPTFLTHEVEANVLTSPRSVMEKNNLFPPR 285
T I T + + TPT + TPT V +P + P
Sbjct: 2333 PTTTPITTTTT---VTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2384
Query: 286 RVESNSSAHPWGLVGKSNPKTPQGTVL-LHTPATSEGQVTIS-TMTGSSPAETKAFTAAW 343
+ + P TP GT TP T+ VT + T TG+ T T
Sbjct: 2385 TTTTTVTPTP----------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2434
Query: 344 SLRNPSPRTSVSAIKTAPAIVWRLAKKPSTAPSTSTTPTVRAKLTMQVHHCVVVKPTPAM 403
++ P+P + + T I P+ P+ + TPT T + V PTP
Sbjct: 2435 TV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT-----TTPITTTTTVTPTPTP 2488
Query: 404 LTTPSPSLTTALLPEELSPSPSVLPPSLPDLHP 436
T +P+ T ++P+P+ P P
Sbjct: 2489 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2521
Score = 68.2 bits (165), Expect = 4e-11
Identities = 81/333 (24%), Positives = 121/333 (36%), Gaps = 39/333 (11%)
Query: 107 TVENIPSMPKRTAKMIPTTTKNNYSPTAAGTERRKEDTPTSSRTLTYYTSTSSRQIVKKY 166
T + P T PTTT + T T TPT ++T T T++ +
Sbjct: 2248 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-----TPTGTQTPTTTPITTTTTVTP-- 2300
Query: 167 TPTPRG-EMKSYSPTQVREKVKYTPSPRGRRVGTYVPSTFMTMETSHAITPRTTVKDSDI 225
TPTP G + + +P V TP+P G + T P T T+ +TP T +
Sbjct: 2301 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPTGTQT 2355
Query: 226 TATYKILETNSLKRIMEETTPTTLKGMFDSTPTFLTHEVEANVLTSPRSVMEKNNLFPPR 285
T I T + + TPT + TPT V +P + P
Sbjct: 2356 PTTTPITTTTT---VTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2407
Query: 286 RVESNSSAHPWGLVGKSNPKTPQGTVL-LHTPATSEGQVTIS-TMTGSSPAETKAFTAAW 343
+ + P TP GT TP T+ VT + T TG+ T T
Sbjct: 2408 TTTTTVTPTP----------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2457
Query: 344 SLRNPSPRTSVSAIKTAPAIVWRLAKKPSTAPSTSTTPTVRAKLTMQVHHCVVVKPTPAM 403
++ P+P + + T I P+ P+ + TPT T + V PTP
Sbjct: 2458 TV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT-----TTPITTTTTVTPTPTP 2511
Query: 404 LTTPSPSLTTALLPEELSPSPSVLPPSLPDLHP 436
T +P+ T ++P+P+ P P
Sbjct: 2512 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2544
Score = 68.2 bits (165), Expect = 4e-11
Identities = 81/333 (24%), Positives = 121/333 (36%), Gaps = 39/333 (11%)
Query: 107 TVENIPSMPKRTAKMIPTTTKNNYSPTAAGTERRKEDTPTSSRTLTYYTSTSSRQIVKKY 166
T + P T PTTT + T T TPT ++T T T++ +
Sbjct: 2271 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-----TPTGTQTPTTTPITTTTTVTP-- 2323
Query: 167 TPTPRG-EMKSYSPTQVREKVKYTPSPRGRRVGTYVPSTFMTMETSHAITPRTTVKDSDI 225
TPTP G + + +P V TP+P G + T P T T+ +TP T +
Sbjct: 2324 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPTGTQT 2378
Query: 226 TATYKILETNSLKRIMEETTPTTLKGMFDSTPTFLTHEVEANVLTSPRSVMEKNNLFPPR 285
T I T + + TPT + TPT V +P + P
Sbjct: 2379 PTTTPITTTTT---VTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2430
Query: 286 RVESNSSAHPWGLVGKSNPKTPQGTVL-LHTPATSEGQVTIS-TMTGSSPAETKAFTAAW 343
+ + P TP GT TP T+ VT + T TG+ T T
Sbjct: 2431 TTTTTVTPTP----------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2480
Query: 344 SLRNPSPRTSVSAIKTAPAIVWRLAKKPSTAPSTSTTPTVRAKLTMQVHHCVVVKPTPAM 403
++ P+P + + T I P+ P+ + TPT T + V PTP
Sbjct: 2481 TV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT-----TTPITTTTTVTPTPTP 2534
Query: 404 LTTPSPSLTTALLPEELSPSPSVLPPSLPDLHP 436
T +P+ T ++P+P+ P P
Sbjct: 2535 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2567
Score = 68.2 bits (165), Expect = 4e-11
Identities = 81/333 (24%), Positives = 121/333 (36%), Gaps = 39/333 (11%)
Query: 107 TVENIPSMPKRTAKMIPTTTKNNYSPTAAGTERRKEDTPTSSRTLTYYTSTSSRQIVKKY 166
T + P T PTTT + T T TPT ++T T T++ +
Sbjct: 2294 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-----TPTGTQTPTTTPITTTTTVTP-- 2346
Query: 167 TPTPRG-EMKSYSPTQVREKVKYTPSPRGRRVGTYVPSTFMTMETSHAITPRTTVKDSDI 225
TPTP G + + +P V TP+P G + T P T T+ +TP T +
Sbjct: 2347 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPTGTQT 2401
Query: 226 TATYKILETNSLKRIMEETTPTTLKGMFDSTPTFLTHEVEANVLTSPRSVMEKNNLFPPR 285
T I T + + TPT + TPT V +P + P
Sbjct: 2402 PTTTPITTTTT---VTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2453
Query: 286 RVESNSSAHPWGLVGKSNPKTPQGTVL-LHTPATSEGQVTIS-TMTGSSPAETKAFTAAW 343
+ + P TP GT TP T+ VT + T TG+ T T
Sbjct: 2454 TTTTTVTPTP----------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2503
Query: 344 SLRNPSPRTSVSAIKTAPAIVWRLAKKPSTAPSTSTTPTVRAKLTMQVHHCVVVKPTPAM 403
++ P+P + + T I P+ P+ + TPT T + V PTP
Sbjct: 2504 TV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT-----TTPITTTTTVTPTPTP 2557
Query: 404 LTTPSPSLTTALLPEELSPSPSVLPPSLPDLHP 436
T +P+ T ++P+P+ P P
Sbjct: 2558 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2590
Score = 68.2 bits (165), Expect = 4e-11
Identities = 81/333 (24%), Positives = 121/333 (36%), Gaps = 39/333 (11%)
Query: 107 TVENIPSMPKRTAKMIPTTTKNNYSPTAAGTERRKEDTPTSSRTLTYYTSTSSRQIVKKY 166
T + P T PTTT + T T TPT ++T T T++ +
Sbjct: 2317 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-----TPTGTQTPTTTPITTTTTVTP-- 2369
Query: 167 TPTPRG-EMKSYSPTQVREKVKYTPSPRGRRVGTYVPSTFMTMETSHAITPRTTVKDSDI 225
TPTP G + + +P V TP+P G + T P T T+ +TP T +
Sbjct: 2370 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPTGTQT 2424
Query: 226 TATYKILETNSLKRIMEETTPTTLKGMFDSTPTFLTHEVEANVLTSPRSVMEKNNLFPPR 285
T I T + + TPT + TPT V +P + P
Sbjct: 2425 PTTTPITTTTT---VTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2476
Query: 286 RVESNSSAHPWGLVGKSNPKTPQGTVL-LHTPATSEGQVTIS-TMTGSSPAETKAFTAAW 343
+ + P TP GT TP T+ VT + T TG+ T T
Sbjct: 2477 TTTTTVTPTP----------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2526
Query: 344 SLRNPSPRTSVSAIKTAPAIVWRLAKKPSTAPSTSTTPTVRAKLTMQVHHCVVVKPTPAM 403
++ P+P + + T I P+ P+ + TPT T + V PTP
Sbjct: 2527 TV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT-----TTPITTTTTVTPTPTP 2580
Query: 404 LTTPSPSLTTALLPEELSPSPSVLPPSLPDLHP 436
T +P+ T ++P+P+ P P
Sbjct: 2581 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2613
Score = 68.2 bits (165), Expect = 4e-11
Identities = 81/333 (24%), Positives = 121/333 (36%), Gaps = 39/333 (11%)
Query: 107 TVENIPSMPKRTAKMIPTTTKNNYSPTAAGTERRKEDTPTSSRTLTYYTSTSSRQIVKKY 166
T + P T PTTT + T T TPT ++T T T++ +
Sbjct: 2340 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-----TPTGTQTPTTTPITTTTTVTP-- 2392
Query: 167 TPTPRG-EMKSYSPTQVREKVKYTPSPRGRRVGTYVPSTFMTMETSHAITPRTTVKDSDI 225
TPTP G + + +P V TP+P G + T P T T+ +TP T +
Sbjct: 2393 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPTGTQT 2447
Query: 226 TATYKILETNSLKRIMEETTPTTLKGMFDSTPTFLTHEVEANVLTSPRSVMEKNNLFPPR 285
T I T + + TPT + TPT V +P + P
Sbjct: 2448 PTTTPITTTTT---VTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2499
Query: 286 RVESNSSAHPWGLVGKSNPKTPQGTVL-LHTPATSEGQVTIS-TMTGSSPAETKAFTAAW 343
+ + P TP GT TP T+ VT + T TG+ T T
Sbjct: 2500 TTTTTVTPTP----------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2549
Query: 344 SLRNPSPRTSVSAIKTAPAIVWRLAKKPSTAPSTSTTPTVRAKLTMQVHHCVVVKPTPAM 403
++ P+P + + T I P+ P+ + TPT T + V PTP
Sbjct: 2550 TV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT-----TTPITTTTTVTPTPTP 2603
Query: 404 LTTPSPSLTTALLPEELSPSPSVLPPSLPDLHP 436
T +P+ T ++P+P+ P P
Sbjct: 2604 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2636
Score = 68.2 bits (165), Expect = 4e-11
Identities = 81/333 (24%), Positives = 121/333 (36%), Gaps = 39/333 (11%)
Query: 107 TVENIPSMPKRTAKMIPTTTKNNYSPTAAGTERRKEDTPTSSRTLTYYTSTSSRQIVKKY 166
T + P T PTTT + T T TPT ++T T T++ +
Sbjct: 2363 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-----TPTGTQTPTTTPITTTTTVTP-- 2415
Query: 167 TPTPRG-EMKSYSPTQVREKVKYTPSPRGRRVGTYVPSTFMTMETSHAITPRTTVKDSDI 225
TPTP G + + +P V TP+P G + T P T T+ +TP T +
Sbjct: 2416 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPTGTQT 2470
Query: 226 TATYKILETNSLKRIMEETTPTTLKGMFDSTPTFLTHEVEANVLTSPRSVMEKNNLFPPR 285
T I T + + TPT + TPT V +P + P
Sbjct: 2471 PTTTPITTTTT---VTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2522
Query: 286 RVESNSSAHPWGLVGKSNPKTPQGTVL-LHTPATSEGQVTIS-TMTGSSPAETKAFTAAW 343
+ + P TP GT TP T+ VT + T TG+ T T
Sbjct: 2523 TTTTTVTPTP----------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2572
Query: 344 SLRNPSPRTSVSAIKTAPAIVWRLAKKPSTAPSTSTTPTVRAKLTMQVHHCVVVKPTPAM 403
++ P+P + + T I P+ P+ + TPT T + V PTP
Sbjct: 2573 TV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT-----TTPITTTTTVTPTPTP 2626
Query: 404 LTTPSPSLTTALLPEELSPSPSVLPPSLPDLHP 436
T +P+ T ++P+P+ P P
Sbjct: 2627 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2659
Score = 68.2 bits (165), Expect = 4e-11
Identities = 81/333 (24%), Positives = 121/333 (36%), Gaps = 39/333 (11%)
Query: 107 TVENIPSMPKRTAKMIPTTTKNNYSPTAAGTERRKEDTPTSSRTLTYYTSTSSRQIVKKY 166
T + P T PTTT + T T TPT ++T T T++ +
Sbjct: 2386 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-----TPTGTQTPTTTPITTTTTVTP-- 2438
Query: 167 TPTPRG-EMKSYSPTQVREKVKYTPSPRGRRVGTYVPSTFMTMETSHAITPRTTVKDSDI 225
TPTP G + + +P V TP+P G + T P T T+ +TP T +
Sbjct: 2439 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPTGTQT 2493
Query: 226 TATYKILETNSLKRIMEETTPTTLKGMFDSTPTFLTHEVEANVLTSPRSVMEKNNLFPPR 285
T I T + + TPT + TPT V +P + P
Sbjct: 2494 PTTTPITTTTT---VTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2545
Query: 286 RVESNSSAHPWGLVGKSNPKTPQGTVL-LHTPATSEGQVTIS-TMTGSSPAETKAFTAAW 343
+ + P TP GT TP T+ VT + T TG+ T T
Sbjct: 2546 TTTTTVTPTP----------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2595
Query: 344 SLRNPSPRTSVSAIKTAPAIVWRLAKKPSTAPSTSTTPTVRAKLTMQVHHCVVVKPTPAM 403
++ P+P + + T I P+ P+ + TPT T + V PTP
Sbjct: 2596 TV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT-----TTPITTTTTVTPTPTP 2649
Query: 404 LTTPSPSLTTALLPEELSPSPSVLPPSLPDLHP 436
T +P+ T ++P+P+ P P
Sbjct: 2650 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2682
Score = 68.2 bits (165), Expect = 4e-11
Identities = 81/333 (24%), Positives = 121/333 (36%), Gaps = 39/333 (11%)
Query: 107 TVENIPSMPKRTAKMIPTTTKNNYSPTAAGTERRKEDTPTSSRTLTYYTSTSSRQIVKKY 166
T + P T PTTT + T T TPT ++T T T++ +
Sbjct: 2409 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-----TPTGTQTPTTTPITTTTTVTP-- 2461
Query: 167 TPTPRG-EMKSYSPTQVREKVKYTPSPRGRRVGTYVPSTFMTMETSHAITPRTTVKDSDI 225
TPTP G + + +P V TP+P G + T P T T+ +TP T +
Sbjct: 2462 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPTGTQT 2516
Query: 226 TATYKILETNSLKRIMEETTPTTLKGMFDSTPTFLTHEVEANVLTSPRSVMEKNNLFPPR 285
T I T + + TPT + TPT V +P + P
Sbjct: 2517 PTTTPITTTTT---VTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2568
Query: 286 RVESNSSAHPWGLVGKSNPKTPQGTVL-LHTPATSEGQVTIS-TMTGSSPAETKAFTAAW 343
+ + P TP GT TP T+ VT + T TG+ T T
Sbjct: 2569 TTTTTVTPTP----------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2618
Query: 344 SLRNPSPRTSVSAIKTAPAIVWRLAKKPSTAPSTSTTPTVRAKLTMQVHHCVVVKPTPAM 403
++ P+P + + T I P+ P+ + TPT T + V PTP
Sbjct: 2619 TV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT-----TTPITTTTTVTPTPTP 2672
Query: 404 LTTPSPSLTTALLPEELSPSPSVLPPSLPDLHP 436
T +P+ T ++P+P+ P P
Sbjct: 2673 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2705
Score = 68.2 bits (165), Expect = 4e-11
Identities = 81/333 (24%), Positives = 121/333 (36%), Gaps = 39/333 (11%)
Query: 107 TVENIPSMPKRTAKMIPTTTKNNYSPTAAGTERRKEDTPTSSRTLTYYTSTSSRQIVKKY 166
T + P T PTTT + T T TPT ++T T T++ +
Sbjct: 2432 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-----TPTGTQTPTTTPITTTTTVTP-- 2484
Query: 167 TPTPRG-EMKSYSPTQVREKVKYTPSPRGRRVGTYVPSTFMTMETSHAITPRTTVKDSDI 225
TPTP G + + +P V TP+P G + T P T T+ +TP T +
Sbjct: 2485 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPTGTQT 2539
Query: 226 TATYKILETNSLKRIMEETTPTTLKGMFDSTPTFLTHEVEANVLTSPRSVMEKNNLFPPR 285
T I T + + TPT + TPT V +P + P
Sbjct: 2540 PTTTPITTTTT---VTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2591
Query: 286 RVESNSSAHPWGLVGKSNPKTPQGTVL-LHTPATSEGQVTIS-TMTGSSPAETKAFTAAW 343
+ + P TP GT TP T+ VT + T TG+ T T
Sbjct: 2592 TTTTTVTPTP----------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2641
Query: 344 SLRNPSPRTSVSAIKTAPAIVWRLAKKPSTAPSTSTTPTVRAKLTMQVHHCVVVKPTPAM 403
++ P+P + + T I P+ P+ + TPT T + V PTP
Sbjct: 2642 TV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT-----TTPITTTTTVTPTPTP 2695
Query: 404 LTTPSPSLTTALLPEELSPSPSVLPPSLPDLHP 436
T +P+ T ++P+P+ P P
Sbjct: 2696 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2728
Score = 68.2 bits (165), Expect = 4e-11
Identities = 81/333 (24%), Positives = 121/333 (36%), Gaps = 39/333 (11%)
Query: 107 TVENIPSMPKRTAKMIPTTTKNNYSPTAAGTERRKEDTPTSSRTLTYYTSTSSRQIVKKY 166
T + P T PTTT + T T TPT ++T T T++ +
Sbjct: 2455 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-----TPTGTQTPTTTPITTTTTVTP-- 2507
Query: 167 TPTPRG-EMKSYSPTQVREKVKYTPSPRGRRVGTYVPSTFMTMETSHAITPRTTVKDSDI 225
TPTP G + + +P V TP+P G + T P T T+ +TP T +
Sbjct: 2508 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPTGTQT 2562
Query: 226 TATYKILETNSLKRIMEETTPTTLKGMFDSTPTFLTHEVEANVLTSPRSVMEKNNLFPPR 285
T I T + + TPT + TPT V +P + P
Sbjct: 2563 PTTTPITTTTT---VTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2614
Query: 286 RVESNSSAHPWGLVGKSNPKTPQGTVL-LHTPATSEGQVTIS-TMTGSSPAETKAFTAAW 343
+ + P TP GT TP T+ VT + T TG+ T T
Sbjct: 2615 TTTTTVTPTP----------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2664
Query: 344 SLRNPSPRTSVSAIKTAPAIVWRLAKKPSTAPSTSTTPTVRAKLTMQVHHCVVVKPTPAM 403
++ P+P + + T I P+ P+ + TPT T + V PTP
Sbjct: 2665 TV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT-----TTPITTTTTVTPTPTP 2718
Query: 404 LTTPSPSLTTALLPEELSPSPSVLPPSLPDLHP 436
T +P+ T ++P+P+ P P
Sbjct: 2719 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2751
Score = 68.2 bits (165), Expect = 4e-11
Identities = 81/333 (24%), Positives = 121/333 (36%), Gaps = 39/333 (11%)
Query: 107 TVENIPSMPKRTAKMIPTTTKNNYSPTAAGTERRKEDTPTSSRTLTYYTSTSSRQIVKKY 166
T + P T PTTT + T T TPT ++T T T++ +
Sbjct: 2478 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-----TPTGTQTPTTTPITTTTTVTP-- 2530
Query: 167 TPTPRG-EMKSYSPTQVREKVKYTPSPRGRRVGTYVPSTFMTMETSHAITPRTTVKDSDI 225
TPTP G + + +P V TP+P G + T P T T+ +TP T +
Sbjct: 2531 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPTGTQT 2585
Query: 226 TATYKILETNSLKRIMEETTPTTLKGMFDSTPTFLTHEVEANVLTSPRSVMEKNNLFPPR 285
T I T + + TPT + TPT V +P + P
Sbjct: 2586 PTTTPITTTTT---VTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2637
Query: 286 RVESNSSAHPWGLVGKSNPKTPQGTVL-LHTPATSEGQVTIS-TMTGSSPAETKAFTAAW 343
+ + P TP GT TP T+ VT + T TG+ T T
Sbjct: 2638 TTTTTVTPTP----------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2687
Query: 344 SLRNPSPRTSVSAIKTAPAIVWRLAKKPSTAPSTSTTPTVRAKLTMQVHHCVVVKPTPAM 403
++ P+P + + T I P+ P+ + TPT T + V PTP
Sbjct: 2688 TV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT-----TTPITTTTTVTPTPTP 2741
Query: 404 LTTPSPSLTTALLPEELSPSPSVLPPSLPDLHP 436
T +P+ T ++P+P+ P P
Sbjct: 2742 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2774
Score = 68.2 bits (165), Expect = 4e-11
Identities = 81/333 (24%), Positives = 121/333 (36%), Gaps = 39/333 (11%)
Query: 107 TVENIPSMPKRTAKMIPTTTKNNYSPTAAGTERRKEDTPTSSRTLTYYTSTSSRQIVKKY 166
T + P T PTTT + T T TPT ++T T T++ +
Sbjct: 2501 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-----TPTGTQTPTTTPITTTTTVTP-- 2553
Query: 167 TPTPRG-EMKSYSPTQVREKVKYTPSPRGRRVGTYVPSTFMTMETSHAITPRTTVKDSDI 225
TPTP G + + +P V TP+P G + T P T T+ +TP T +
Sbjct: 2554 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPTGTQT 2608
Query: 226 TATYKILETNSLKRIMEETTPTTLKGMFDSTPTFLTHEVEANVLTSPRSVMEKNNLFPPR 285
T I T + + TPT + TPT V +P + P
Sbjct: 2609 PTTTPITTTTT---VTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2660
Query: 286 RVESNSSAHPWGLVGKSNPKTPQGTVL-LHTPATSEGQVTIS-TMTGSSPAETKAFTAAW 343
+ + P TP GT TP T+ VT + T TG+ T T
Sbjct: 2661 TTTTTVTPTP----------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2710
Query: 344 SLRNPSPRTSVSAIKTAPAIVWRLAKKPSTAPSTSTTPTVRAKLTMQVHHCVVVKPTPAM 403
++ P+P + + T I P+ P+ + TPT T + V PTP
Sbjct: 2711 TV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT-----TTPITTTTTVTPTPTP 2764
Query: 404 LTTPSPSLTTALLPEELSPSPSVLPPSLPDLHP 436
T +P+ T ++P+P+ P P
Sbjct: 2765 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2797
Score = 68.2 bits (165), Expect = 4e-11
Identities = 81/333 (24%), Positives = 121/333 (36%), Gaps = 39/333 (11%)
Query: 107 TVENIPSMPKRTAKMIPTTTKNNYSPTAAGTERRKEDTPTSSRTLTYYTSTSSRQIVKKY 166
T + P T PTTT + T T TPT ++T T T++ +
Sbjct: 2524 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-----TPTGTQTPTTTPITTTTTVTP-- 2576
Query: 167 TPTPRG-EMKSYSPTQVREKVKYTPSPRGRRVGTYVPSTFMTMETSHAITPRTTVKDSDI 225
TPTP G + + +P V TP+P G + T P T T+ +TP T +
Sbjct: 2577 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPTGTQT 2631
Query: 226 TATYKILETNSLKRIMEETTPTTLKGMFDSTPTFLTHEVEANVLTSPRSVMEKNNLFPPR 285
T I T + + TPT + TPT V +P + P
Sbjct: 2632 PTTTPITTTTT---VTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2683
Query: 286 RVESNSSAHPWGLVGKSNPKTPQGTVL-LHTPATSEGQVTIS-TMTGSSPAETKAFTAAW 343
+ + P TP GT TP T+ VT + T TG+ T T
Sbjct: 2684 TTTTTVTPTP----------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2733
Query: 344 SLRNPSPRTSVSAIKTAPAIVWRLAKKPSTAPSTSTTPTVRAKLTMQVHHCVVVKPTPAM 403
++ P+P + + T I P+ P+ + TPT T + V PTP
Sbjct: 2734 TV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT-----TTPITTTTTVTPTPTP 2787
Query: 404 LTTPSPSLTTALLPEELSPSPSVLPPSLPDLHP 436
T +P+ T ++P+P+ P P
Sbjct: 2788 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2820
Score = 68.2 bits (165), Expect = 4e-11
Identities = 81/333 (24%), Positives = 121/333 (36%), Gaps = 39/333 (11%)
Query: 107 TVENIPSMPKRTAKMIPTTTKNNYSPTAAGTERRKEDTPTSSRTLTYYTSTSSRQIVKKY 166
T + P T PTTT + T T TPT ++T T T++ +
Sbjct: 2547 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-----TPTGTQTPTTTPITTTTTVTP-- 2599
Query: 167 TPTPRG-EMKSYSPTQVREKVKYTPSPRGRRVGTYVPSTFMTMETSHAITPRTTVKDSDI 225
TPTP G + + +P V TP+P G + T P T T+ +TP T +
Sbjct: 2600 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPTGTQT 2654
Query: 226 TATYKILETNSLKRIMEETTPTTLKGMFDSTPTFLTHEVEANVLTSPRSVMEKNNLFPPR 285
T I T + + TPT + TPT V +P + P
Sbjct: 2655 PTTTPITTTTT---VTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2706
Query: 286 RVESNSSAHPWGLVGKSNPKTPQGTVL-LHTPATSEGQVTIS-TMTGSSPAETKAFTAAW 343
+ + P TP GT TP T+ VT + T TG+ T T
Sbjct: 2707 TTTTTVTPTP----------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2756
Query: 344 SLRNPSPRTSVSAIKTAPAIVWRLAKKPSTAPSTSTTPTVRAKLTMQVHHCVVVKPTPAM 403
++ P+P + + T I P+ P+ + TPT T + V PTP
Sbjct: 2757 TV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT-----TTPITTTTTVTPTPTP 2810
Query: 404 LTTPSPSLTTALLPEELSPSPSVLPPSLPDLHP 436
T +P+ T ++P+P+ P P
Sbjct: 2811 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2843
Score = 68.2 bits (165), Expect = 4e-11
Identities = 81/333 (24%), Positives = 121/333 (36%), Gaps = 39/333 (11%)
Query: 107 TVENIPSMPKRTAKMIPTTTKNNYSPTAAGTERRKEDTPTSSRTLTYYTSTSSRQIVKKY 166
T + P T PTTT + T T TPT ++T T T++ +
Sbjct: 2570 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-----TPTGTQTPTTTPITTTTTVTP-- 2622
Query: 167 TPTPRG-EMKSYSPTQVREKVKYTPSPRGRRVGTYVPSTFMTMETSHAITPRTTVKDSDI 225
TPTP G + + +P V TP+P G + T P T T+ +TP T +
Sbjct: 2623 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPTGTQT 2677
Query: 226 TATYKILETNSLKRIMEETTPTTLKGMFDSTPTFLTHEVEANVLTSPRSVMEKNNLFPPR 285
T I T + + TPT + TPT V +P + P
Sbjct: 2678 PTTTPITTTTT---VTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2729
Query: 286 RVESNSSAHPWGLVGKSNPKTPQGTVL-LHTPATSEGQVTIS-TMTGSSPAETKAFTAAW 343
+ + P TP GT TP T+ VT + T TG+ T T
Sbjct: 2730 TTTTTVTPTP----------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2779
Query: 344 SLRNPSPRTSVSAIKTAPAIVWRLAKKPSTAPSTSTTPTVRAKLTMQVHHCVVVKPTPAM 403
++ P+P + + T I P+ P+ + TPT T + V PTP
Sbjct: 2780 TV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT-----TTPITTTTTVTPTPTP 2833
Query: 404 LTTPSPSLTTALLPEELSPSPSVLPPSLPDLHP 436
T +P+ T ++P+P+ P P
Sbjct: 2834 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2866
Score = 68.2 bits (165), Expect = 4e-11
Identities = 81/333 (24%), Positives = 121/333 (36%), Gaps = 39/333 (11%)
Query: 107 TVENIPSMPKRTAKMIPTTTKNNYSPTAAGTERRKEDTPTSSRTLTYYTSTSSRQIVKKY 166
T + P T PTTT + T T TPT ++T T T++ +
Sbjct: 2593 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-----TPTGTQTPTTTPITTTTTVTP-- 2645
Query: 167 TPTPRG-EMKSYSPTQVREKVKYTPSPRGRRVGTYVPSTFMTMETSHAITPRTTVKDSDI 225
TPTP G + + +P V TP+P G + T P T T+ +TP T +
Sbjct: 2646 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPTGTQT 2700
Query: 226 TATYKILETNSLKRIMEETTPTTLKGMFDSTPTFLTHEVEANVLTSPRSVMEKNNLFPPR 285
T I T + + TPT + TPT V +P + P
Sbjct: 2701 PTTTPITTTTT---VTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2752
Query: 286 RVESNSSAHPWGLVGKSNPKTPQGTVL-LHTPATSEGQVTIS-TMTGSSPAETKAFTAAW 343
+ + P TP GT TP T+ VT + T TG+ T T
Sbjct: 2753 TTTTTVTPTP----------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2802
Query: 344 SLRNPSPRTSVSAIKTAPAIVWRLAKKPSTAPSTSTTPTVRAKLTMQVHHCVVVKPTPAM 403
++ P+P + + T I P+ P+ + TPT T + V PTP
Sbjct: 2803 TV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT-----TTPITTTTTVTPTPTP 2856
Query: 404 LTTPSPSLTTALLPEELSPSPSVLPPSLPDLHP 436
T +P+ T ++P+P+ P P
Sbjct: 2857 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2889
Score = 68.2 bits (165), Expect = 4e-11
Identities = 81/333 (24%), Positives = 121/333 (36%), Gaps = 39/333 (11%)
Query: 107 TVENIPSMPKRTAKMIPTTTKNNYSPTAAGTERRKEDTPTSSRTLTYYTSTSSRQIVKKY 166
T + P T PTTT + T T TPT ++T T T++ +
Sbjct: 2616 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-----TPTGTQTPTTTPITTTTTVTP-- 2668
Query: 167 TPTPRG-EMKSYSPTQVREKVKYTPSPRGRRVGTYVPSTFMTMETSHAITPRTTVKDSDI 225
TPTP G + + +P V TP+P G + T P T T+ +TP T +
Sbjct: 2669 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPTGTQT 2723
Query: 226 TATYKILETNSLKRIMEETTPTTLKGMFDSTPTFLTHEVEANVLTSPRSVMEKNNLFPPR 285
T I T + + TPT + TPT V +P + P
Sbjct: 2724 PTTTPITTTTT---VTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2775
Query: 286 RVESNSSAHPWGLVGKSNPKTPQGTVL-LHTPATSEGQVTIS-TMTGSSPAETKAFTAAW 343
+ + P TP GT TP T+ VT + T TG+ T T
Sbjct: 2776 TTTTTVTPTP----------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2825
Query: 344 SLRNPSPRTSVSAIKTAPAIVWRLAKKPSTAPSTSTTPTVRAKLTMQVHHCVVVKPTPAM 403
++ P+P + + T I P+ P+ + TPT T + V PTP
Sbjct: 2826 TV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT-----TTPITTTTTVTPTPTP 2879
Query: 404 LTTPSPSLTTALLPEELSPSPSVLPPSLPDLHP 436
T +P+ T ++P+P+ P P
Sbjct: 2880 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2912
Score = 68.2 bits (165), Expect = 4e-11
Identities = 81/333 (24%), Positives = 121/333 (36%), Gaps = 39/333 (11%)
Query: 107 TVENIPSMPKRTAKMIPTTTKNNYSPTAAGTERRKEDTPTSSRTLTYYTSTSSRQIVKKY 166
T + P T PTTT + T T TPT ++T T T++ +
Sbjct: 2639 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-----TPTGTQTPTTTPITTTTTVTP-- 2691
Query: 167 TPTPRG-EMKSYSPTQVREKVKYTPSPRGRRVGTYVPSTFMTMETSHAITPRTTVKDSDI 225
TPTP G + + +P V TP+P G + T P T T+ +TP T +
Sbjct: 2692 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPTGTQT 2746
Query: 226 TATYKILETNSLKRIMEETTPTTLKGMFDSTPTFLTHEVEANVLTSPRSVMEKNNLFPPR 285
T I T + + TPT + TPT V +P + P
Sbjct: 2747 PTTTPITTTTT---VTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2798
Query: 286 RVESNSSAHPWGLVGKSNPKTPQGTVL-LHTPATSEGQVTIS-TMTGSSPAETKAFTAAW 343
+ + P TP GT TP T+ VT + T TG+ T T
Sbjct: 2799 TTTTTVTPTP----------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2848
Query: 344 SLRNPSPRTSVSAIKTAPAIVWRLAKKPSTAPSTSTTPTVRAKLTMQVHHCVVVKPTPAM 403
++ P+P + + T I P+ P+ + TPT T + V PTP
Sbjct: 2849 TV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT-----TTPITTTTTVTPTPTP 2902
Query: 404 LTTPSPSLTTALLPEELSPSPSVLPPSLPDLHP 436
T +P+ T ++P+P+ P P
Sbjct: 2903 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2935
Score = 68.2 bits (165), Expect = 4e-11
Identities = 81/333 (24%), Positives = 121/333 (36%), Gaps = 39/333 (11%)
Query: 107 TVENIPSMPKRTAKMIPTTTKNNYSPTAAGTERRKEDTPTSSRTLTYYTSTSSRQIVKKY 166
T + P T PTTT + T T TPT ++T T T++ +
Sbjct: 2662 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-----TPTGTQTPTTTPITTTTTVTP-- 2714
Query: 167 TPTPRG-EMKSYSPTQVREKVKYTPSPRGRRVGTYVPSTFMTMETSHAITPRTTVKDSDI 225
TPTP G + + +P V TP+P G + T P T T+ +TP T +
Sbjct: 2715 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPTGTQT 2769
Query: 226 TATYKILETNSLKRIMEETTPTTLKGMFDSTPTFLTHEVEANVLTSPRSVMEKNNLFPPR 285
T I T + + TPT + TPT V +P + P
Sbjct: 2770 PTTTPITTTTT---VTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2821
Query: 286 RVESNSSAHPWGLVGKSNPKTPQGTVL-LHTPATSEGQVTIS-TMTGSSPAETKAFTAAW 343
+ + P TP GT TP T+ VT + T TG+ T T
Sbjct: 2822 TTTTTVTPTP----------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2871
Query: 344 SLRNPSPRTSVSAIKTAPAIVWRLAKKPSTAPSTSTTPTVRAKLTMQVHHCVVVKPTPAM 403
++ P+P + + T I P+ P+ + TPT T + V PTP
Sbjct: 2872 TV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT-----TTPITTTTTVTPTPTP 2925
Query: 404 LTTPSPSLTTALLPEELSPSPSVLPPSLPDLHP 436
T +P+ T ++P+P+ P P
Sbjct: 2926 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2958
Score = 68.2 bits (165), Expect = 4e-11
Identities = 81/333 (24%), Positives = 121/333 (36%), Gaps = 39/333 (11%)
Query: 107 TVENIPSMPKRTAKMIPTTTKNNYSPTAAGTERRKEDTPTSSRTLTYYTSTSSRQIVKKY 166
T + P T PTTT + T T TPT ++T T T++ +
Sbjct: 2685 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-----TPTGTQTPTTTPITTTTTVTP-- 2737
Query: 167 TPTPRG-EMKSYSPTQVREKVKYTPSPRGRRVGTYVPSTFMTMETSHAITPRTTVKDSDI 225
TPTP G + + +P V TP+P G + T P T T+ +TP T +
Sbjct: 2738 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPTGTQT 2792
Query: 226 TATYKILETNSLKRIMEETTPTTLKGMFDSTPTFLTHEVEANVLTSPRSVMEKNNLFPPR 285
T I T + + TPT + TPT V +P + P
Sbjct: 2793 PTTTPITTTTT---VTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2844
Query: 286 RVESNSSAHPWGLVGKSNPKTPQGTVL-LHTPATSEGQVTIS-TMTGSSPAETKAFTAAW 343
+ + P TP GT TP T+ VT + T TG+ T T
Sbjct: 2845 TTTTTVTPTP----------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2894
Query: 344 SLRNPSPRTSVSAIKTAPAIVWRLAKKPSTAPSTSTTPTVRAKLTMQVHHCVVVKPTPAM 403
++ P+P + + T I P+ P+ + TPT T + V PTP
Sbjct: 2895 TV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT-----TTPITTTTTVTPTPTP 2948
Query: 404 LTTPSPSLTTALLPEELSPSPSVLPPSLPDLHP 436
T +P+ T ++P+P+ P P
Sbjct: 2949 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 2981
Score = 68.2 bits (165), Expect = 4e-11
Identities = 81/333 (24%), Positives = 121/333 (36%), Gaps = 39/333 (11%)
Query: 107 TVENIPSMPKRTAKMIPTTTKNNYSPTAAGTERRKEDTPTSSRTLTYYTSTSSRQIVKKY 166
T + P T PTTT + T T TPT ++T T T++ +
Sbjct: 2708 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-----TPTGTQTPTTTPITTTTTVTP-- 2760
Query: 167 TPTPRG-EMKSYSPTQVREKVKYTPSPRGRRVGTYVPSTFMTMETSHAITPRTTVKDSDI 225
TPTP G + + +P V TP+P G + T P T T+ +TP T +
Sbjct: 2761 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPTGTQT 2815
Query: 226 TATYKILETNSLKRIMEETTPTTLKGMFDSTPTFLTHEVEANVLTSPRSVMEKNNLFPPR 285
T I T + + TPT + TPT V +P + P
Sbjct: 2816 PTTTPITTTTT---VTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2867
Query: 286 RVESNSSAHPWGLVGKSNPKTPQGTVL-LHTPATSEGQVTIS-TMTGSSPAETKAFTAAW 343
+ + P TP GT TP T+ VT + T TG+ T T
Sbjct: 2868 TTTTTVTPTP----------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2917
Query: 344 SLRNPSPRTSVSAIKTAPAIVWRLAKKPSTAPSTSTTPTVRAKLTMQVHHCVVVKPTPAM 403
++ P+P + + T I P+ P+ + TPT T + V PTP
Sbjct: 2918 TV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT-----TTPITTTTTVTPTPTP 2971
Query: 404 LTTPSPSLTTALLPEELSPSPSVLPPSLPDLHP 436
T +P+ T ++P+P+ P P
Sbjct: 2972 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3004
Score = 68.2 bits (165), Expect = 4e-11
Identities = 81/333 (24%), Positives = 121/333 (36%), Gaps = 39/333 (11%)
Query: 107 TVENIPSMPKRTAKMIPTTTKNNYSPTAAGTERRKEDTPTSSRTLTYYTSTSSRQIVKKY 166
T + P T PTTT + T T TPT ++T T T++ +
Sbjct: 2731 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-----TPTGTQTPTTTPITTTTTVTP-- 2783
Query: 167 TPTPRG-EMKSYSPTQVREKVKYTPSPRGRRVGTYVPSTFMTMETSHAITPRTTVKDSDI 225
TPTP G + + +P V TP+P G + T P T T+ +TP T +
Sbjct: 2784 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPTGTQT 2838
Query: 226 TATYKILETNSLKRIMEETTPTTLKGMFDSTPTFLTHEVEANVLTSPRSVMEKNNLFPPR 285
T I T + + TPT + TPT V +P + P
Sbjct: 2839 PTTTPITTTTT---VTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2890
Query: 286 RVESNSSAHPWGLVGKSNPKTPQGTVL-LHTPATSEGQVTIS-TMTGSSPAETKAFTAAW 343
+ + P TP GT TP T+ VT + T TG+ T T
Sbjct: 2891 TTTTTVTPTP----------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2940
Query: 344 SLRNPSPRTSVSAIKTAPAIVWRLAKKPSTAPSTSTTPTVRAKLTMQVHHCVVVKPTPAM 403
++ P+P + + T I P+ P+ + TPT T + V PTP
Sbjct: 2941 TV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT-----TTPITTTTTVTPTPTP 2994
Query: 404 LTTPSPSLTTALLPEELSPSPSVLPPSLPDLHP 436
T +P+ T ++P+P+ P P
Sbjct: 2995 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3027
Score = 68.2 bits (165), Expect = 4e-11
Identities = 81/333 (24%), Positives = 121/333 (36%), Gaps = 39/333 (11%)
Query: 107 TVENIPSMPKRTAKMIPTTTKNNYSPTAAGTERRKEDTPTSSRTLTYYTSTSSRQIVKKY 166
T + P T PTTT + T T TPT ++T T T++ +
Sbjct: 2754 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-----TPTGTQTPTTTPITTTTTVTP-- 2806
Query: 167 TPTPRG-EMKSYSPTQVREKVKYTPSPRGRRVGTYVPSTFMTMETSHAITPRTTVKDSDI 225
TPTP G + + +P V TP+P G + T P T T+ +TP T +
Sbjct: 2807 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPTGTQT 2861
Query: 226 TATYKILETNSLKRIMEETTPTTLKGMFDSTPTFLTHEVEANVLTSPRSVMEKNNLFPPR 285
T I T + + TPT + TPT V +P + P
Sbjct: 2862 PTTTPITTTTT---VTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2913
Query: 286 RVESNSSAHPWGLVGKSNPKTPQGTVL-LHTPATSEGQVTIS-TMTGSSPAETKAFTAAW 343
+ + P TP GT TP T+ VT + T TG+ T T
Sbjct: 2914 TTTTTVTPTP----------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2963
Query: 344 SLRNPSPRTSVSAIKTAPAIVWRLAKKPSTAPSTSTTPTVRAKLTMQVHHCVVVKPTPAM 403
++ P+P + + T I P+ P+ + TPT T + V PTP
Sbjct: 2964 TV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT-----TTPITTTTTVTPTPTP 3017
Query: 404 LTTPSPSLTTALLPEELSPSPSVLPPSLPDLHP 436
T +P+ T ++P+P+ P P
Sbjct: 3018 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3050
Score = 68.2 bits (165), Expect = 4e-11
Identities = 81/333 (24%), Positives = 121/333 (36%), Gaps = 39/333 (11%)
Query: 107 TVENIPSMPKRTAKMIPTTTKNNYSPTAAGTERRKEDTPTSSRTLTYYTSTSSRQIVKKY 166
T + P T PTTT + T T TPT ++T T T++ +
Sbjct: 2777 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-----TPTGTQTPTTTPITTTTTVTP-- 2829
Query: 167 TPTPRG-EMKSYSPTQVREKVKYTPSPRGRRVGTYVPSTFMTMETSHAITPRTTVKDSDI 225
TPTP G + + +P V TP+P G + T P T T+ +TP T +
Sbjct: 2830 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPTGTQT 2884
Query: 226 TATYKILETNSLKRIMEETTPTTLKGMFDSTPTFLTHEVEANVLTSPRSVMEKNNLFPPR 285
T I T + + TPT + TPT V +P + P
Sbjct: 2885 PTTTPITTTTT---VTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2936
Query: 286 RVESNSSAHPWGLVGKSNPKTPQGTVL-LHTPATSEGQVTIS-TMTGSSPAETKAFTAAW 343
+ + P TP GT TP T+ VT + T TG+ T T
Sbjct: 2937 TTTTTVTPTP----------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 2986
Query: 344 SLRNPSPRTSVSAIKTAPAIVWRLAKKPSTAPSTSTTPTVRAKLTMQVHHCVVVKPTPAM 403
++ P+P + + T I P+ P+ + TPT T + V PTP
Sbjct: 2987 TV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT-----TTPITTTTTVTPTPTP 3040
Query: 404 LTTPSPSLTTALLPEELSPSPSVLPPSLPDLHP 436
T +P+ T ++P+P+ P P
Sbjct: 3041 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3073
Score = 68.2 bits (165), Expect = 4e-11
Identities = 81/333 (24%), Positives = 121/333 (36%), Gaps = 39/333 (11%)
Query: 107 TVENIPSMPKRTAKMIPTTTKNNYSPTAAGTERRKEDTPTSSRTLTYYTSTSSRQIVKKY 166
T + P T PTTT + T T TPT ++T T T++ +
Sbjct: 2800 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-----TPTGTQTPTTTPITTTTTVTP-- 2852
Query: 167 TPTPRG-EMKSYSPTQVREKVKYTPSPRGRRVGTYVPSTFMTMETSHAITPRTTVKDSDI 225
TPTP G + + +P V TP+P G + T P T T+ +TP T +
Sbjct: 2853 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPTGTQT 2907
Query: 226 TATYKILETNSLKRIMEETTPTTLKGMFDSTPTFLTHEVEANVLTSPRSVMEKNNLFPPR 285
T I T + + TPT + TPT V +P + P
Sbjct: 2908 PTTTPITTTTT---VTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2959
Query: 286 RVESNSSAHPWGLVGKSNPKTPQGTVL-LHTPATSEGQVTIS-TMTGSSPAETKAFTAAW 343
+ + P TP GT TP T+ VT + T TG+ T T
Sbjct: 2960 TTTTTVTPTP----------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3009
Query: 344 SLRNPSPRTSVSAIKTAPAIVWRLAKKPSTAPSTSTTPTVRAKLTMQVHHCVVVKPTPAM 403
++ P+P + + T I P+ P+ + TPT T + V PTP
Sbjct: 3010 TV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT-----TTPITTTTTVTPTPTP 3063
Query: 404 LTTPSPSLTTALLPEELSPSPSVLPPSLPDLHP 436
T +P+ T ++P+P+ P P
Sbjct: 3064 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3096
Score = 68.2 bits (165), Expect = 4e-11
Identities = 81/333 (24%), Positives = 121/333 (36%), Gaps = 39/333 (11%)
Query: 107 TVENIPSMPKRTAKMIPTTTKNNYSPTAAGTERRKEDTPTSSRTLTYYTSTSSRQIVKKY 166
T + P T PTTT + T T TPT ++T T T++ +
Sbjct: 2823 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-----TPTGTQTPTTTPITTTTTVTP-- 2875
Query: 167 TPTPRG-EMKSYSPTQVREKVKYTPSPRGRRVGTYVPSTFMTMETSHAITPRTTVKDSDI 225
TPTP G + + +P V TP+P G + T P T T+ +TP T +
Sbjct: 2876 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPTGTQT 2930
Query: 226 TATYKILETNSLKRIMEETTPTTLKGMFDSTPTFLTHEVEANVLTSPRSVMEKNNLFPPR 285
T I T + + TPT + TPT V +P + P
Sbjct: 2931 PTTTPITTTTT---VTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPI 2982
Query: 286 RVESNSSAHPWGLVGKSNPKTPQGTVL-LHTPATSEGQVTIS-TMTGSSPAETKAFTAAW 343
+ + P TP GT TP T+ VT + T TG+ T T
Sbjct: 2983 TTTTTVTPTP----------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3032
Query: 344 SLRNPSPRTSVSAIKTAPAIVWRLAKKPSTAPSTSTTPTVRAKLTMQVHHCVVVKPTPAM 403
++ P+P + + T I P+ P+ + TPT T + V PTP
Sbjct: 3033 TV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT-----TTPITTTTTVTPTPTP 3086
Query: 404 LTTPSPSLTTALLPEELSPSPSVLPPSLPDLHP 436
T +P+ T ++P+P+ P P
Sbjct: 3087 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3119
Score = 68.2 bits (165), Expect = 4e-11
Identities = 81/333 (24%), Positives = 121/333 (36%), Gaps = 39/333 (11%)
Query: 107 TVENIPSMPKRTAKMIPTTTKNNYSPTAAGTERRKEDTPTSSRTLTYYTSTSSRQIVKKY 166
T + P T PTTT + T T TPT ++T T T++ +
Sbjct: 2846 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-----TPTGTQTPTTTPITTTTTVTP-- 2898
Query: 167 TPTPRG-EMKSYSPTQVREKVKYTPSPRGRRVGTYVPSTFMTMETSHAITPRTTVKDSDI 225
TPTP G + + +P V TP+P G + T P T T+ +TP T +
Sbjct: 2899 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPTGTQT 2953
Query: 226 TATYKILETNSLKRIMEETTPTTLKGMFDSTPTFLTHEVEANVLTSPRSVMEKNNLFPPR 285
T I T + + TPT + TPT V +P + P
Sbjct: 2954 PTTTPITTTTT---VTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3005
Query: 286 RVESNSSAHPWGLVGKSNPKTPQGTVL-LHTPATSEGQVTIS-TMTGSSPAETKAFTAAW 343
+ + P TP GT TP T+ VT + T TG+ T T
Sbjct: 3006 TTTTTVTPTP----------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3055
Query: 344 SLRNPSPRTSVSAIKTAPAIVWRLAKKPSTAPSTSTTPTVRAKLTMQVHHCVVVKPTPAM 403
++ P+P + + T I P+ P+ + TPT T + V PTP
Sbjct: 3056 TV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT-----TTPITTTTTVTPTPTP 3109
Query: 404 LTTPSPSLTTALLPEELSPSPSVLPPSLPDLHP 436
T +P+ T ++P+P+ P P
Sbjct: 3110 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3142
Score = 68.2 bits (165), Expect = 4e-11
Identities = 81/333 (24%), Positives = 121/333 (36%), Gaps = 39/333 (11%)
Query: 107 TVENIPSMPKRTAKMIPTTTKNNYSPTAAGTERRKEDTPTSSRTLTYYTSTSSRQIVKKY 166
T + P T PTTT + T T TPT ++T T T++ +
Sbjct: 2869 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-----TPTGTQTPTTTPITTTTTVTP-- 2921
Query: 167 TPTPRG-EMKSYSPTQVREKVKYTPSPRGRRVGTYVPSTFMTMETSHAITPRTTVKDSDI 225
TPTP G + + +P V TP+P G + T P T T+ +TP T +
Sbjct: 2922 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPTGTQT 2976
Query: 226 TATYKILETNSLKRIMEETTPTTLKGMFDSTPTFLTHEVEANVLTSPRSVMEKNNLFPPR 285
T I T + + TPT + TPT V +P + P
Sbjct: 2977 PTTTPITTTTT---VTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3028
Query: 286 RVESNSSAHPWGLVGKSNPKTPQGTVL-LHTPATSEGQVTIS-TMTGSSPAETKAFTAAW 343
+ + P TP GT TP T+ VT + T TG+ T T
Sbjct: 3029 TTTTTVTPTP----------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3078
Query: 344 SLRNPSPRTSVSAIKTAPAIVWRLAKKPSTAPSTSTTPTVRAKLTMQVHHCVVVKPTPAM 403
++ P+P + + T I P+ P+ + TPT T + V PTP
Sbjct: 3079 TV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT-----TTPITTTTTVTPTPTP 3132
Query: 404 LTTPSPSLTTALLPEELSPSPSVLPPSLPDLHP 436
T +P+ T ++P+P+ P P
Sbjct: 3133 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3165
Score = 68.2 bits (165), Expect = 4e-11
Identities = 81/333 (24%), Positives = 121/333 (36%), Gaps = 39/333 (11%)
Query: 107 TVENIPSMPKRTAKMIPTTTKNNYSPTAAGTERRKEDTPTSSRTLTYYTSTSSRQIVKKY 166
T + P T PTTT + T T TPT ++T T T++ +
Sbjct: 2892 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-----TPTGTQTPTTTPITTTTTVTP-- 2944
Query: 167 TPTPRG-EMKSYSPTQVREKVKYTPSPRGRRVGTYVPSTFMTMETSHAITPRTTVKDSDI 225
TPTP G + + +P V TP+P G + T P T T+ +TP T +
Sbjct: 2945 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPTGTQT 2999
Query: 226 TATYKILETNSLKRIMEETTPTTLKGMFDSTPTFLTHEVEANVLTSPRSVMEKNNLFPPR 285
T I T + + TPT + TPT V +P + P
Sbjct: 3000 PTTTPITTTTT---VTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3051
Query: 286 RVESNSSAHPWGLVGKSNPKTPQGTVL-LHTPATSEGQVTIS-TMTGSSPAETKAFTAAW 343
+ + P TP GT TP T+ VT + T TG+ T T
Sbjct: 3052 TTTTTVTPTP----------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3101
Query: 344 SLRNPSPRTSVSAIKTAPAIVWRLAKKPSTAPSTSTTPTVRAKLTMQVHHCVVVKPTPAM 403
++ P+P + + T I P+ P+ + TPT T + V PTP
Sbjct: 3102 TV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT-----TTPITTTTTVTPTPTP 3155
Query: 404 LTTPSPSLTTALLPEELSPSPSVLPPSLPDLHP 436
T +P+ T ++P+P+ P P
Sbjct: 3156 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3188
Score = 68.2 bits (165), Expect = 4e-11
Identities = 81/333 (24%), Positives = 121/333 (36%), Gaps = 39/333 (11%)
Query: 107 TVENIPSMPKRTAKMIPTTTKNNYSPTAAGTERRKEDTPTSSRTLTYYTSTSSRQIVKKY 166
T + P T PTTT + T T TPT ++T T T++ +
Sbjct: 2915 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-----TPTGTQTPTTTPITTTTTVTP-- 2967
Query: 167 TPTPRG-EMKSYSPTQVREKVKYTPSPRGRRVGTYVPSTFMTMETSHAITPRTTVKDSDI 225
TPTP G + + +P V TP+P G + T P T T+ +TP T +
Sbjct: 2968 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPTGTQT 3022
Query: 226 TATYKILETNSLKRIMEETTPTTLKGMFDSTPTFLTHEVEANVLTSPRSVMEKNNLFPPR 285
T I T + + TPT + TPT V +P + P
Sbjct: 3023 PTTTPITTTTT---VTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3074
Query: 286 RVESNSSAHPWGLVGKSNPKTPQGTVL-LHTPATSEGQVTIS-TMTGSSPAETKAFTAAW 343
+ + P TP GT TP T+ VT + T TG+ T T
Sbjct: 3075 TTTTTVTPTP----------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3124
Query: 344 SLRNPSPRTSVSAIKTAPAIVWRLAKKPSTAPSTSTTPTVRAKLTMQVHHCVVVKPTPAM 403
++ P+P + + T I P+ P+ + TPT T + V PTP
Sbjct: 3125 TV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT-----TTPITTTTTVTPTPTP 3178
Query: 404 LTTPSPSLTTALLPEELSPSPSVLPPSLPDLHP 436
T +P+ T ++P+P+ P P
Sbjct: 3179 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3211
Score = 68.2 bits (165), Expect = 4e-11
Identities = 81/333 (24%), Positives = 121/333 (36%), Gaps = 39/333 (11%)
Query: 107 TVENIPSMPKRTAKMIPTTTKNNYSPTAAGTERRKEDTPTSSRTLTYYTSTSSRQIVKKY 166
T + P T PTTT + T T TPT ++T T T++ +
Sbjct: 2938 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-----TPTGTQTPTTTPITTTTTVTP-- 2990
Query: 167 TPTPRG-EMKSYSPTQVREKVKYTPSPRGRRVGTYVPSTFMTMETSHAITPRTTVKDSDI 225
TPTP G + + +P V TP+P G + T P T T+ +TP T +
Sbjct: 2991 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPTGTQT 3045
Query: 226 TATYKILETNSLKRIMEETTPTTLKGMFDSTPTFLTHEVEANVLTSPRSVMEKNNLFPPR 285
T I T + + TPT + TPT V +P + P
Sbjct: 3046 PTTTPITTTTT---VTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3097
Query: 286 RVESNSSAHPWGLVGKSNPKTPQGTVL-LHTPATSEGQVTIS-TMTGSSPAETKAFTAAW 343
+ + P TP GT TP T+ VT + T TG+ T T
Sbjct: 3098 TTTTTVTPTP----------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3147
Query: 344 SLRNPSPRTSVSAIKTAPAIVWRLAKKPSTAPSTSTTPTVRAKLTMQVHHCVVVKPTPAM 403
++ P+P + + T I P+ P+ + TPT T + V PTP
Sbjct: 3148 TV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT-----TTPITTTTTVTPTPTP 3201
Query: 404 LTTPSPSLTTALLPEELSPSPSVLPPSLPDLHP 436
T +P+ T ++P+P+ P P
Sbjct: 3202 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3234
Score = 68.2 bits (165), Expect = 4e-11
Identities = 81/333 (24%), Positives = 121/333 (36%), Gaps = 39/333 (11%)
Query: 107 TVENIPSMPKRTAKMIPTTTKNNYSPTAAGTERRKEDTPTSSRTLTYYTSTSSRQIVKKY 166
T + P T PTTT + T T TPT ++T T T++ +
Sbjct: 2961 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-----TPTGTQTPTTTPITTTTTVTP-- 3013
Query: 167 TPTPRG-EMKSYSPTQVREKVKYTPSPRGRRVGTYVPSTFMTMETSHAITPRTTVKDSDI 225
TPTP G + + +P V TP+P G + T P T T+ +TP T +
Sbjct: 3014 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPTGTQT 3068
Query: 226 TATYKILETNSLKRIMEETTPTTLKGMFDSTPTFLTHEVEANVLTSPRSVMEKNNLFPPR 285
T I T + + TPT + TPT V +P + P
Sbjct: 3069 PTTTPITTTTT---VTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3120
Query: 286 RVESNSSAHPWGLVGKSNPKTPQGTVL-LHTPATSEGQVTIS-TMTGSSPAETKAFTAAW 343
+ + P TP GT TP T+ VT + T TG+ T T
Sbjct: 3121 TTTTTVTPTP----------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3170
Query: 344 SLRNPSPRTSVSAIKTAPAIVWRLAKKPSTAPSTSTTPTVRAKLTMQVHHCVVVKPTPAM 403
++ P+P + + T I P+ P+ + TPT T + V PTP
Sbjct: 3171 TV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT-----TTPITTTTTVTPTPTP 3224
Query: 404 LTTPSPSLTTALLPEELSPSPSVLPPSLPDLHP 436
T +P+ T ++P+P+ P P
Sbjct: 3225 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3257
Score = 68.2 bits (165), Expect = 4e-11
Identities = 81/333 (24%), Positives = 121/333 (36%), Gaps = 39/333 (11%)
Query: 107 TVENIPSMPKRTAKMIPTTTKNNYSPTAAGTERRKEDTPTSSRTLTYYTSTSSRQIVKKY 166
T + P T PTTT + T T TPT ++T T T++ +
Sbjct: 2984 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-----TPTGTQTPTTTPITTTTTVTP-- 3036
Query: 167 TPTPRG-EMKSYSPTQVREKVKYTPSPRGRRVGTYVPSTFMTMETSHAITPRTTVKDSDI 225
TPTP G + + +P V TP+P G + T P T T+ +TP T +
Sbjct: 3037 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPTGTQT 3091
Query: 226 TATYKILETNSLKRIMEETTPTTLKGMFDSTPTFLTHEVEANVLTSPRSVMEKNNLFPPR 285
T I T + + TPT + TPT V +P + P
Sbjct: 3092 PTTTPITTTTT---VTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3143
Query: 286 RVESNSSAHPWGLVGKSNPKTPQGTVL-LHTPATSEGQVTIS-TMTGSSPAETKAFTAAW 343
+ + P TP GT TP T+ VT + T TG+ T T
Sbjct: 3144 TTTTTVTPTP----------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3193
Query: 344 SLRNPSPRTSVSAIKTAPAIVWRLAKKPSTAPSTSTTPTVRAKLTMQVHHCVVVKPTPAM 403
++ P+P + + T I P+ P+ + TPT T + V PTP
Sbjct: 3194 TV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT-----TTPITTTTTVTPTPTP 3247
Query: 404 LTTPSPSLTTALLPEELSPSPSVLPPSLPDLHP 436
T +P+ T ++P+P+ P P
Sbjct: 3248 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3280
Score = 68.2 bits (165), Expect = 4e-11
Identities = 81/333 (24%), Positives = 121/333 (36%), Gaps = 39/333 (11%)
Query: 107 TVENIPSMPKRTAKMIPTTTKNNYSPTAAGTERRKEDTPTSSRTLTYYTSTSSRQIVKKY 166
T + P T PTTT + T T TPT ++T T T++ +
Sbjct: 3007 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-----TPTGTQTPTTTPITTTTTVTP-- 3059
Query: 167 TPTPRG-EMKSYSPTQVREKVKYTPSPRGRRVGTYVPSTFMTMETSHAITPRTTVKDSDI 225
TPTP G + + +P V TP+P G + T P T T+ +TP T +
Sbjct: 3060 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPTGTQT 3114
Query: 226 TATYKILETNSLKRIMEETTPTTLKGMFDSTPTFLTHEVEANVLTSPRSVMEKNNLFPPR 285
T I T + + TPT + TPT V +P + P
Sbjct: 3115 PTTTPITTTTT---VTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3166
Query: 286 RVESNSSAHPWGLVGKSNPKTPQGTVL-LHTPATSEGQVTIS-TMTGSSPAETKAFTAAW 343
+ + P TP GT TP T+ VT + T TG+ T T
Sbjct: 3167 TTTTTVTPTP----------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3216
Query: 344 SLRNPSPRTSVSAIKTAPAIVWRLAKKPSTAPSTSTTPTVRAKLTMQVHHCVVVKPTPAM 403
++ P+P + + T I P+ P+ + TPT T + V PTP
Sbjct: 3217 TV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT-----TTPITTTTTVTPTPTP 3270
Query: 404 LTTPSPSLTTALLPEELSPSPSVLPPSLPDLHP 436
T +P+ T ++P+P+ P P
Sbjct: 3271 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3303
Score = 68.2 bits (165), Expect = 4e-11
Identities = 81/333 (24%), Positives = 121/333 (36%), Gaps = 39/333 (11%)
Query: 107 TVENIPSMPKRTAKMIPTTTKNNYSPTAAGTERRKEDTPTSSRTLTYYTSTSSRQIVKKY 166
T + P T PTTT + T T TPT ++T T T++ +
Sbjct: 3030 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-----TPTGTQTPTTTPITTTTTVTP-- 3082
Query: 167 TPTPRG-EMKSYSPTQVREKVKYTPSPRGRRVGTYVPSTFMTMETSHAITPRTTVKDSDI 225
TPTP G + + +P V TP+P G + T P T T+ +TP T +
Sbjct: 3083 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPTGTQT 3137
Query: 226 TATYKILETNSLKRIMEETTPTTLKGMFDSTPTFLTHEVEANVLTSPRSVMEKNNLFPPR 285
T I T + + TPT + TPT V +P + P
Sbjct: 3138 PTTTPITTTTT---VTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3189
Query: 286 RVESNSSAHPWGLVGKSNPKTPQGTVL-LHTPATSEGQVTIS-TMTGSSPAETKAFTAAW 343
+ + P TP GT TP T+ VT + T TG+ T T
Sbjct: 3190 TTTTTVTPTP----------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3239
Query: 344 SLRNPSPRTSVSAIKTAPAIVWRLAKKPSTAPSTSTTPTVRAKLTMQVHHCVVVKPTPAM 403
++ P+P + + T I P+ P+ + TPT T + V PTP
Sbjct: 3240 TV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT-----TTPITTTTTVTPTPTP 3293
Query: 404 LTTPSPSLTTALLPEELSPSPSVLPPSLPDLHP 436
T +P+ T ++P+P+ P P
Sbjct: 3294 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3326
Score = 68.2 bits (165), Expect = 4e-11
Identities = 81/333 (24%), Positives = 121/333 (36%), Gaps = 39/333 (11%)
Query: 107 TVENIPSMPKRTAKMIPTTTKNNYSPTAAGTERRKEDTPTSSRTLTYYTSTSSRQIVKKY 166
T + P T PTTT + T T TPT ++T T T++ +
Sbjct: 3053 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-----TPTGTQTPTTTPITTTTTVTP-- 3105
Query: 167 TPTPRG-EMKSYSPTQVREKVKYTPSPRGRRVGTYVPSTFMTMETSHAITPRTTVKDSDI 225
TPTP G + + +P V TP+P G + T P T T+ +TP T +
Sbjct: 3106 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPTGTQT 3160
Query: 226 TATYKILETNSLKRIMEETTPTTLKGMFDSTPTFLTHEVEANVLTSPRSVMEKNNLFPPR 285
T I T + + TPT + TPT V +P + P
Sbjct: 3161 PTTTPITTTTT---VTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3212
Query: 286 RVESNSSAHPWGLVGKSNPKTPQGTVL-LHTPATSEGQVTIS-TMTGSSPAETKAFTAAW 343
+ + P TP GT TP T+ VT + T TG+ T T
Sbjct: 3213 TTTTTVTPTP----------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3262
Query: 344 SLRNPSPRTSVSAIKTAPAIVWRLAKKPSTAPSTSTTPTVRAKLTMQVHHCVVVKPTPAM 403
++ P+P + + T I P+ P+ + TPT T + V PTP
Sbjct: 3263 TV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT-----TTPITTTTTVTPTPTP 3316
Query: 404 LTTPSPSLTTALLPEELSPSPSVLPPSLPDLHP 436
T +P+ T ++P+P+ P P
Sbjct: 3317 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3349
Score = 68.2 bits (165), Expect = 4e-11
Identities = 81/333 (24%), Positives = 121/333 (36%), Gaps = 39/333 (11%)
Query: 107 TVENIPSMPKRTAKMIPTTTKNNYSPTAAGTERRKEDTPTSSRTLTYYTSTSSRQIVKKY 166
T + P T PTTT + T T TPT ++T T T++ +
Sbjct: 3076 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-----TPTGTQTPTTTPITTTTTVTP-- 3128
Query: 167 TPTPRG-EMKSYSPTQVREKVKYTPSPRGRRVGTYVPSTFMTMETSHAITPRTTVKDSDI 225
TPTP G + + +P V TP+P G + T P T T+ +TP T +
Sbjct: 3129 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPTGTQT 3183
Query: 226 TATYKILETNSLKRIMEETTPTTLKGMFDSTPTFLTHEVEANVLTSPRSVMEKNNLFPPR 285
T I T + + TPT + TPT V +P + P
Sbjct: 3184 PTTTPITTTTT---VTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3235
Query: 286 RVESNSSAHPWGLVGKSNPKTPQGTVL-LHTPATSEGQVTIS-TMTGSSPAETKAFTAAW 343
+ + P TP GT TP T+ VT + T TG+ T T
Sbjct: 3236 TTTTTVTPTP----------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3285
Query: 344 SLRNPSPRTSVSAIKTAPAIVWRLAKKPSTAPSTSTTPTVRAKLTMQVHHCVVVKPTPAM 403
++ P+P + + T I P+ P+ + TPT T + V PTP
Sbjct: 3286 TV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT-----TTPITTTTTVTPTPTP 3339
Query: 404 LTTPSPSLTTALLPEELSPSPSVLPPSLPDLHP 436
T +P+ T ++P+P+ P P
Sbjct: 3340 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3372
Score = 68.2 bits (165), Expect = 4e-11
Identities = 81/333 (24%), Positives = 121/333 (36%), Gaps = 39/333 (11%)
Query: 107 TVENIPSMPKRTAKMIPTTTKNNYSPTAAGTERRKEDTPTSSRTLTYYTSTSSRQIVKKY 166
T + P T PTTT + T T TPT ++T T T++ +
Sbjct: 3099 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-----TPTGTQTPTTTPITTTTTVTP-- 3151
Query: 167 TPTPRG-EMKSYSPTQVREKVKYTPSPRGRRVGTYVPSTFMTMETSHAITPRTTVKDSDI 225
TPTP G + + +P V TP+P G + T P T T+ +TP T +
Sbjct: 3152 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPTGTQT 3206
Query: 226 TATYKILETNSLKRIMEETTPTTLKGMFDSTPTFLTHEVEANVLTSPRSVMEKNNLFPPR 285
T I T + + TPT + TPT V +P + P
Sbjct: 3207 PTTTPITTTTT---VTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3258
Query: 286 RVESNSSAHPWGLVGKSNPKTPQGTVL-LHTPATSEGQVTIS-TMTGSSPAETKAFTAAW 343
+ + P TP GT TP T+ VT + T TG+ T T
Sbjct: 3259 TTTTTVTPTP----------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3308
Query: 344 SLRNPSPRTSVSAIKTAPAIVWRLAKKPSTAPSTSTTPTVRAKLTMQVHHCVVVKPTPAM 403
++ P+P + + T I P+ P+ + TPT T + V PTP
Sbjct: 3309 TV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT-----TTPITTTTTVTPTPTP 3362
Query: 404 LTTPSPSLTTALLPEELSPSPSVLPPSLPDLHP 436
T +P+ T ++P+P+ P P
Sbjct: 3363 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3395
Score = 68.2 bits (165), Expect = 4e-11
Identities = 81/333 (24%), Positives = 121/333 (36%), Gaps = 39/333 (11%)
Query: 107 TVENIPSMPKRTAKMIPTTTKNNYSPTAAGTERRKEDTPTSSRTLTYYTSTSSRQIVKKY 166
T + P T PTTT + T T TPT ++T T T++ +
Sbjct: 3122 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-----TPTGTQTPTTTPITTTTTVTP-- 3174
Query: 167 TPTPRG-EMKSYSPTQVREKVKYTPSPRGRRVGTYVPSTFMTMETSHAITPRTTVKDSDI 225
TPTP G + + +P V TP+P G + T P T T+ +TP T +
Sbjct: 3175 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPTGTQT 3229
Query: 226 TATYKILETNSLKRIMEETTPTTLKGMFDSTPTFLTHEVEANVLTSPRSVMEKNNLFPPR 285
T I T + + TPT + TPT V +P + P
Sbjct: 3230 PTTTPITTTTT---VTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3281
Query: 286 RVESNSSAHPWGLVGKSNPKTPQGTVL-LHTPATSEGQVTIS-TMTGSSPAETKAFTAAW 343
+ + P TP GT TP T+ VT + T TG+ T T
Sbjct: 3282 TTTTTVTPTP----------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3331
Query: 344 SLRNPSPRTSVSAIKTAPAIVWRLAKKPSTAPSTSTTPTVRAKLTMQVHHCVVVKPTPAM 403
++ P+P + + T I P+ P+ + TPT T + V PTP
Sbjct: 3332 TV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT-----TTPITTTTTVTPTPTP 3385
Query: 404 LTTPSPSLTTALLPEELSPSPSVLPPSLPDLHP 436
T +P+ T ++P+P+ P P
Sbjct: 3386 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3418
Score = 68.2 bits (165), Expect = 4e-11
Identities = 81/333 (24%), Positives = 121/333 (36%), Gaps = 39/333 (11%)
Query: 107 TVENIPSMPKRTAKMIPTTTKNNYSPTAAGTERRKEDTPTSSRTLTYYTSTSSRQIVKKY 166
T + P T PTTT + T T TPT ++T T T++ +
Sbjct: 3145 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-----TPTGTQTPTTTPITTTTTVTP-- 3197
Query: 167 TPTPRG-EMKSYSPTQVREKVKYTPSPRGRRVGTYVPSTFMTMETSHAITPRTTVKDSDI 225
TPTP G + + +P V TP+P G + T P T T+ +TP T +
Sbjct: 3198 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPTGTQT 3252
Query: 226 TATYKILETNSLKRIMEETTPTTLKGMFDSTPTFLTHEVEANVLTSPRSVMEKNNLFPPR 285
T I T + + TPT + TPT V +P + P
Sbjct: 3253 PTTTPITTTTT---VTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3304
Query: 286 RVESNSSAHPWGLVGKSNPKTPQGTVL-LHTPATSEGQVTIS-TMTGSSPAETKAFTAAW 343
+ + P TP GT TP T+ VT + T TG+ T T
Sbjct: 3305 TTTTTVTPTP----------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3354
Query: 344 SLRNPSPRTSVSAIKTAPAIVWRLAKKPSTAPSTSTTPTVRAKLTMQVHHCVVVKPTPAM 403
++ P+P + + T I P+ P+ + TPT T + V PTP
Sbjct: 3355 TV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT-----TTPITTTTTVTPTPTP 3408
Query: 404 LTTPSPSLTTALLPEELSPSPSVLPPSLPDLHP 436
T +P+ T ++P+P+ P P
Sbjct: 3409 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3441
Score = 68.2 bits (165), Expect = 4e-11
Identities = 81/333 (24%), Positives = 121/333 (36%), Gaps = 39/333 (11%)
Query: 107 TVENIPSMPKRTAKMIPTTTKNNYSPTAAGTERRKEDTPTSSRTLTYYTSTSSRQIVKKY 166
T + P T PTTT + T T TPT ++T T T++ +
Sbjct: 3168 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-----TPTGTQTPTTTPITTTTTVTP-- 3220
Query: 167 TPTPRG-EMKSYSPTQVREKVKYTPSPRGRRVGTYVPSTFMTMETSHAITPRTTVKDSDI 225
TPTP G + + +P V TP+P G + T P T T+ +TP T +
Sbjct: 3221 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPTGTQT 3275
Query: 226 TATYKILETNSLKRIMEETTPTTLKGMFDSTPTFLTHEVEANVLTSPRSVMEKNNLFPPR 285
T I T + + TPT + TPT V +P + P
Sbjct: 3276 PTTTPITTTTT---VTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3327
Query: 286 RVESNSSAHPWGLVGKSNPKTPQGTVL-LHTPATSEGQVTIS-TMTGSSPAETKAFTAAW 343
+ + P TP GT TP T+ VT + T TG+ T T
Sbjct: 3328 TTTTTVTPTP----------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3377
Query: 344 SLRNPSPRTSVSAIKTAPAIVWRLAKKPSTAPSTSTTPTVRAKLTMQVHHCVVVKPTPAM 403
++ P+P + + T I P+ P+ + TPT T + V PTP
Sbjct: 3378 TV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT-----TTPITTTTTVTPTPTP 3431
Query: 404 LTTPSPSLTTALLPEELSPSPSVLPPSLPDLHP 436
T +P+ T ++P+P+ P P
Sbjct: 3432 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3464
Score = 68.2 bits (165), Expect = 4e-11
Identities = 81/333 (24%), Positives = 121/333 (36%), Gaps = 39/333 (11%)
Query: 107 TVENIPSMPKRTAKMIPTTTKNNYSPTAAGTERRKEDTPTSSRTLTYYTSTSSRQIVKKY 166
T + P T PTTT + T T TPT ++T T T++ +
Sbjct: 3191 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-----TPTGTQTPTTTPITTTTTVTP-- 3243
Query: 167 TPTPRG-EMKSYSPTQVREKVKYTPSPRGRRVGTYVPSTFMTMETSHAITPRTTVKDSDI 225
TPTP G + + +P V TP+P G + T P T T+ +TP T +
Sbjct: 3244 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPTGTQT 3298
Query: 226 TATYKILETNSLKRIMEETTPTTLKGMFDSTPTFLTHEVEANVLTSPRSVMEKNNLFPPR 285
T I T + + TPT + TPT V +P + P
Sbjct: 3299 PTTTPITTTTT---VTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3350
Query: 286 RVESNSSAHPWGLVGKSNPKTPQGTVL-LHTPATSEGQVTIS-TMTGSSPAETKAFTAAW 343
+ + P TP GT TP T+ VT + T TG+ T T
Sbjct: 3351 TTTTTVTPTP----------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3400
Query: 344 SLRNPSPRTSVSAIKTAPAIVWRLAKKPSTAPSTSTTPTVRAKLTMQVHHCVVVKPTPAM 403
++ P+P + + T I P+ P+ + TPT T + V PTP
Sbjct: 3401 TV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT-----TTPITTTTTVTPTPTP 3454
Query: 404 LTTPSPSLTTALLPEELSPSPSVLPPSLPDLHP 436
T +P+ T ++P+P+ P P
Sbjct: 3455 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3487
Score = 68.2 bits (165), Expect = 4e-11
Identities = 81/333 (24%), Positives = 121/333 (36%), Gaps = 39/333 (11%)
Query: 107 TVENIPSMPKRTAKMIPTTTKNNYSPTAAGTERRKEDTPTSSRTLTYYTSTSSRQIVKKY 166
T + P T PTTT + T T TPT ++T T T++ +
Sbjct: 3214 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-----TPTGTQTPTTTPITTTTTVTP-- 3266
Query: 167 TPTPRG-EMKSYSPTQVREKVKYTPSPRGRRVGTYVPSTFMTMETSHAITPRTTVKDSDI 225
TPTP G + + +P V TP+P G + T P T T+ +TP T +
Sbjct: 3267 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPTGTQT 3321
Query: 226 TATYKILETNSLKRIMEETTPTTLKGMFDSTPTFLTHEVEANVLTSPRSVMEKNNLFPPR 285
T I T + + TPT + TPT V +P + P
Sbjct: 3322 PTTTPITTTTT---VTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3373
Query: 286 RVESNSSAHPWGLVGKSNPKTPQGTVL-LHTPATSEGQVTIS-TMTGSSPAETKAFTAAW 343
+ + P TP GT TP T+ VT + T TG+ T T
Sbjct: 3374 TTTTTVTPTP----------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3423
Query: 344 SLRNPSPRTSVSAIKTAPAIVWRLAKKPSTAPSTSTTPTVRAKLTMQVHHCVVVKPTPAM 403
++ P+P + + T I P+ P+ + TPT T + V PTP
Sbjct: 3424 TV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT-----TTPITTTTTVTPTPTP 3477
Query: 404 LTTPSPSLTTALLPEELSPSPSVLPPSLPDLHP 436
T +P+ T ++P+P+ P P
Sbjct: 3478 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3510
Score = 68.2 bits (165), Expect = 4e-11
Identities = 81/333 (24%), Positives = 121/333 (36%), Gaps = 39/333 (11%)
Query: 107 TVENIPSMPKRTAKMIPTTTKNNYSPTAAGTERRKEDTPTSSRTLTYYTSTSSRQIVKKY 166
T + P T PTTT + T T TPT ++T T T++ +
Sbjct: 3237 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-----TPTGTQTPTTTPITTTTTVTP-- 3289
Query: 167 TPTPRG-EMKSYSPTQVREKVKYTPSPRGRRVGTYVPSTFMTMETSHAITPRTTVKDSDI 225
TPTP G + + +P V TP+P G + T P T T+ +TP T +
Sbjct: 3290 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPTGTQT 3344
Query: 226 TATYKILETNSLKRIMEETTPTTLKGMFDSTPTFLTHEVEANVLTSPRSVMEKNNLFPPR 285
T I T + + TPT + TPT V +P + P
Sbjct: 3345 PTTTPITTTTT---VTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3396
Query: 286 RVESNSSAHPWGLVGKSNPKTPQGTVL-LHTPATSEGQVTIS-TMTGSSPAETKAFTAAW 343
+ + P TP GT TP T+ VT + T TG+ T T
Sbjct: 3397 TTTTTVTPTP----------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3446
Query: 344 SLRNPSPRTSVSAIKTAPAIVWRLAKKPSTAPSTSTTPTVRAKLTMQVHHCVVVKPTPAM 403
++ P+P + + T I P+ P+ + TPT T + V PTP
Sbjct: 3447 TV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT-----TTPITTTTTVTPTPTP 3500
Query: 404 LTTPSPSLTTALLPEELSPSPSVLPPSLPDLHP 436
T +P+ T ++P+P+ P P
Sbjct: 3501 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3533
Score = 68.2 bits (165), Expect = 4e-11
Identities = 81/333 (24%), Positives = 121/333 (36%), Gaps = 39/333 (11%)
Query: 107 TVENIPSMPKRTAKMIPTTTKNNYSPTAAGTERRKEDTPTSSRTLTYYTSTSSRQIVKKY 166
T + P T PTTT + T T TPT ++T T T++ +
Sbjct: 3260 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-----TPTGTQTPTTTPITTTTTVTP-- 3312
Query: 167 TPTPRG-EMKSYSPTQVREKVKYTPSPRGRRVGTYVPSTFMTMETSHAITPRTTVKDSDI 225
TPTP G + + +P V TP+P G + T P T T+ +TP T +
Sbjct: 3313 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPTGTQT 3367
Query: 226 TATYKILETNSLKRIMEETTPTTLKGMFDSTPTFLTHEVEANVLTSPRSVMEKNNLFPPR 285
T I T + + TPT + TPT V +P + P
Sbjct: 3368 PTTTPITTTTT---VTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3419
Query: 286 RVESNSSAHPWGLVGKSNPKTPQGTVL-LHTPATSEGQVTIS-TMTGSSPAETKAFTAAW 343
+ + P TP GT TP T+ VT + T TG+ T T
Sbjct: 3420 TTTTTVTPTP----------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3469
Query: 344 SLRNPSPRTSVSAIKTAPAIVWRLAKKPSTAPSTSTTPTVRAKLTMQVHHCVVVKPTPAM 403
++ P+P + + T I P+ P+ + TPT T + V PTP
Sbjct: 3470 TV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT-----TTPITTTTTVTPTPTP 3523
Query: 404 LTTPSPSLTTALLPEELSPSPSVLPPSLPDLHP 436
T +P+ T ++P+P+ P P
Sbjct: 3524 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3556
Score = 68.2 bits (165), Expect = 4e-11
Identities = 81/333 (24%), Positives = 121/333 (36%), Gaps = 39/333 (11%)
Query: 107 TVENIPSMPKRTAKMIPTTTKNNYSPTAAGTERRKEDTPTSSRTLTYYTSTSSRQIVKKY 166
T + P T PTTT + T T TPT ++T T T++ +
Sbjct: 3283 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-----TPTGTQTPTTTPITTTTTVTP-- 3335
Query: 167 TPTPRG-EMKSYSPTQVREKVKYTPSPRGRRVGTYVPSTFMTMETSHAITPRTTVKDSDI 225
TPTP G + + +P V TP+P G + T P T T+ +TP T +
Sbjct: 3336 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPTGTQT 3390
Query: 226 TATYKILETNSLKRIMEETTPTTLKGMFDSTPTFLTHEVEANVLTSPRSVMEKNNLFPPR 285
T I T + + TPT + TPT V +P + P
Sbjct: 3391 PTTTPITTTTT---VTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3442
Query: 286 RVESNSSAHPWGLVGKSNPKTPQGTVL-LHTPATSEGQVTIS-TMTGSSPAETKAFTAAW 343
+ + P TP GT TP T+ VT + T TG+ T T
Sbjct: 3443 TTTTTVTPTP----------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3492
Query: 344 SLRNPSPRTSVSAIKTAPAIVWRLAKKPSTAPSTSTTPTVRAKLTMQVHHCVVVKPTPAM 403
++ P+P + + T I P+ P+ + TPT T + V PTP
Sbjct: 3493 TV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT-----TTPITTTTTVTPTPTP 3546
Query: 404 LTTPSPSLTTALLPEELSPSPSVLPPSLPDLHP 436
T +P+ T ++P+P+ P P
Sbjct: 3547 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3579
Score = 68.2 bits (165), Expect = 4e-11
Identities = 81/333 (24%), Positives = 121/333 (36%), Gaps = 39/333 (11%)
Query: 107 TVENIPSMPKRTAKMIPTTTKNNYSPTAAGTERRKEDTPTSSRTLTYYTSTSSRQIVKKY 166
T + P T PTTT + T T TPT ++T T T++ +
Sbjct: 3306 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-----TPTGTQTPTTTPITTTTTVTP-- 3358
Query: 167 TPTPRG-EMKSYSPTQVREKVKYTPSPRGRRVGTYVPSTFMTMETSHAITPRTTVKDSDI 225
TPTP G + + +P V TP+P G + T P T T+ +TP T +
Sbjct: 3359 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPTGTQT 3413
Query: 226 TATYKILETNSLKRIMEETTPTTLKGMFDSTPTFLTHEVEANVLTSPRSVMEKNNLFPPR 285
T I T + + TPT + TPT V +P + P
Sbjct: 3414 PTTTPITTTTT---VTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3465
Query: 286 RVESNSSAHPWGLVGKSNPKTPQGTVL-LHTPATSEGQVTIS-TMTGSSPAETKAFTAAW 343
+ + P TP GT TP T+ VT + T TG+ T T
Sbjct: 3466 TTTTTVTPTP----------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3515
Query: 344 SLRNPSPRTSVSAIKTAPAIVWRLAKKPSTAPSTSTTPTVRAKLTMQVHHCVVVKPTPAM 403
++ P+P + + T I P+ P+ + TPT T + V PTP
Sbjct: 3516 TV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT-----TTPITTTTTVTPTPTP 3569
Query: 404 LTTPSPSLTTALLPEELSPSPSVLPPSLPDLHP 436
T +P+ T ++P+P+ P P
Sbjct: 3570 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3602
Score = 68.2 bits (165), Expect = 4e-11
Identities = 81/333 (24%), Positives = 121/333 (36%), Gaps = 39/333 (11%)
Query: 107 TVENIPSMPKRTAKMIPTTTKNNYSPTAAGTERRKEDTPTSSRTLTYYTSTSSRQIVKKY 166
T + P T PTTT + T T TPT ++T T T++ +
Sbjct: 3329 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-----TPTGTQTPTTTPITTTTTVTP-- 3381
Query: 167 TPTPRG-EMKSYSPTQVREKVKYTPSPRGRRVGTYVPSTFMTMETSHAITPRTTVKDSDI 225
TPTP G + + +P V TP+P G + T P T T+ +TP T +
Sbjct: 3382 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPTGTQT 3436
Query: 226 TATYKILETNSLKRIMEETTPTTLKGMFDSTPTFLTHEVEANVLTSPRSVMEKNNLFPPR 285
T I T + + TPT + TPT V +P + P
Sbjct: 3437 PTTTPITTTTT---VTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3488
Query: 286 RVESNSSAHPWGLVGKSNPKTPQGTVL-LHTPATSEGQVTIS-TMTGSSPAETKAFTAAW 343
+ + P TP GT TP T+ VT + T TG+ T T
Sbjct: 3489 TTTTTVTPTP----------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3538
Query: 344 SLRNPSPRTSVSAIKTAPAIVWRLAKKPSTAPSTSTTPTVRAKLTMQVHHCVVVKPTPAM 403
++ P+P + + T I P+ P+ + TPT T + V PTP
Sbjct: 3539 TV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT-----TTPITTTTTVTPTPTP 3592
Query: 404 LTTPSPSLTTALLPEELSPSPSVLPPSLPDLHP 436
T +P+ T ++P+P+ P P
Sbjct: 3593 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3625
Score = 68.2 bits (165), Expect = 4e-11
Identities = 81/333 (24%), Positives = 121/333 (36%), Gaps = 39/333 (11%)
Query: 107 TVENIPSMPKRTAKMIPTTTKNNYSPTAAGTERRKEDTPTSSRTLTYYTSTSSRQIVKKY 166
T + P T PTTT + T T TPT ++T T T++ +
Sbjct: 3352 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-----TPTGTQTPTTTPITTTTTVTP-- 3404
Query: 167 TPTPRG-EMKSYSPTQVREKVKYTPSPRGRRVGTYVPSTFMTMETSHAITPRTTVKDSDI 225
TPTP G + + +P V TP+P G + T P T T+ +TP T +
Sbjct: 3405 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPTGTQT 3459
Query: 226 TATYKILETNSLKRIMEETTPTTLKGMFDSTPTFLTHEVEANVLTSPRSVMEKNNLFPPR 285
T I T + + TPT + TPT V +P + P
Sbjct: 3460 PTTTPITTTTT---VTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3511
Query: 286 RVESNSSAHPWGLVGKSNPKTPQGTVL-LHTPATSEGQVTIS-TMTGSSPAETKAFTAAW 343
+ + P TP GT TP T+ VT + T TG+ T T
Sbjct: 3512 TTTTTVTPTP----------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3561
Query: 344 SLRNPSPRTSVSAIKTAPAIVWRLAKKPSTAPSTSTTPTVRAKLTMQVHHCVVVKPTPAM 403
++ P+P + + T I P+ P+ + TPT T + V PTP
Sbjct: 3562 TV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT-----TTPITTTTTVTPTPTP 3615
Query: 404 LTTPSPSLTTALLPEELSPSPSVLPPSLPDLHP 436
T +P+ T ++P+P+ P P
Sbjct: 3616 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3648
Score = 68.2 bits (165), Expect = 4e-11
Identities = 81/333 (24%), Positives = 121/333 (36%), Gaps = 39/333 (11%)
Query: 107 TVENIPSMPKRTAKMIPTTTKNNYSPTAAGTERRKEDTPTSSRTLTYYTSTSSRQIVKKY 166
T + P T PTTT + T T TPT ++T T T++ +
Sbjct: 3375 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-----TPTGTQTPTTTPITTTTTVTP-- 3427
Query: 167 TPTPRG-EMKSYSPTQVREKVKYTPSPRGRRVGTYVPSTFMTMETSHAITPRTTVKDSDI 225
TPTP G + + +P V TP+P G + T P T T+ +TP T +
Sbjct: 3428 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPTGTQT 3482
Query: 226 TATYKILETNSLKRIMEETTPTTLKGMFDSTPTFLTHEVEANVLTSPRSVMEKNNLFPPR 285
T I T + + TPT + TPT V +P + P
Sbjct: 3483 PTTTPITTTTT---VTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3534
Query: 286 RVESNSSAHPWGLVGKSNPKTPQGTVL-LHTPATSEGQVTIS-TMTGSSPAETKAFTAAW 343
+ + P TP GT TP T+ VT + T TG+ T T
Sbjct: 3535 TTTTTVTPTP----------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3584
Query: 344 SLRNPSPRTSVSAIKTAPAIVWRLAKKPSTAPSTSTTPTVRAKLTMQVHHCVVVKPTPAM 403
++ P+P + + T I P+ P+ + TPT T + V PTP
Sbjct: 3585 TV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT-----TTPITTTTTVTPTPTP 3638
Query: 404 LTTPSPSLTTALLPEELSPSPSVLPPSLPDLHP 436
T +P+ T ++P+P+ P P
Sbjct: 3639 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3671
Score = 68.2 bits (165), Expect = 4e-11
Identities = 81/333 (24%), Positives = 121/333 (36%), Gaps = 39/333 (11%)
Query: 107 TVENIPSMPKRTAKMIPTTTKNNYSPTAAGTERRKEDTPTSSRTLTYYTSTSSRQIVKKY 166
T + P T PTTT + T T TPT ++T T T++ +
Sbjct: 3398 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-----TPTGTQTPTTTPITTTTTVTP-- 3450
Query: 167 TPTPRG-EMKSYSPTQVREKVKYTPSPRGRRVGTYVPSTFMTMETSHAITPRTTVKDSDI 225
TPTP G + + +P V TP+P G + T P T T+ +TP T +
Sbjct: 3451 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPTGTQT 3505
Query: 226 TATYKILETNSLKRIMEETTPTTLKGMFDSTPTFLTHEVEANVLTSPRSVMEKNNLFPPR 285
T I T + + TPT + TPT V +P + P
Sbjct: 3506 PTTTPITTTTT---VTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3557
Query: 286 RVESNSSAHPWGLVGKSNPKTPQGTVL-LHTPATSEGQVTIS-TMTGSSPAETKAFTAAW 343
+ + P TP GT TP T+ VT + T TG+ T T
Sbjct: 3558 TTTTTVTPTP----------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3607
Query: 344 SLRNPSPRTSVSAIKTAPAIVWRLAKKPSTAPSTSTTPTVRAKLTMQVHHCVVVKPTPAM 403
++ P+P + + T I P+ P+ + TPT T + V PTP
Sbjct: 3608 TV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT-----TTPITTTTTVTPTPTP 3661
Query: 404 LTTPSPSLTTALLPEELSPSPSVLPPSLPDLHP 436
T +P+ T ++P+P+ P P
Sbjct: 3662 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3694
Score = 68.2 bits (165), Expect = 4e-11
Identities = 81/333 (24%), Positives = 121/333 (36%), Gaps = 39/333 (11%)
Query: 107 TVENIPSMPKRTAKMIPTTTKNNYSPTAAGTERRKEDTPTSSRTLTYYTSTSSRQIVKKY 166
T + P T PTTT + T T TPT ++T T T++ +
Sbjct: 3421 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-----TPTGTQTPTTTPITTTTTVTP-- 3473
Query: 167 TPTPRG-EMKSYSPTQVREKVKYTPSPRGRRVGTYVPSTFMTMETSHAITPRTTVKDSDI 225
TPTP G + + +P V TP+P G + T P T T+ +TP T +
Sbjct: 3474 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPTGTQT 3528
Query: 226 TATYKILETNSLKRIMEETTPTTLKGMFDSTPTFLTHEVEANVLTSPRSVMEKNNLFPPR 285
T I T + + TPT + TPT V +P + P
Sbjct: 3529 PTTTPITTTTT---VTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3580
Query: 286 RVESNSSAHPWGLVGKSNPKTPQGTVL-LHTPATSEGQVTIS-TMTGSSPAETKAFTAAW 343
+ + P TP GT TP T+ VT + T TG+ T T
Sbjct: 3581 TTTTTVTPTP----------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3630
Query: 344 SLRNPSPRTSVSAIKTAPAIVWRLAKKPSTAPSTSTTPTVRAKLTMQVHHCVVVKPTPAM 403
++ P+P + + T I P+ P+ + TPT T + V PTP
Sbjct: 3631 TV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT-----TTPITTTTTVTPTPTP 3684
Query: 404 LTTPSPSLTTALLPEELSPSPSVLPPSLPDLHP 436
T +P+ T ++P+P+ P P
Sbjct: 3685 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3717
Score = 68.2 bits (165), Expect = 4e-11
Identities = 81/333 (24%), Positives = 121/333 (36%), Gaps = 39/333 (11%)
Query: 107 TVENIPSMPKRTAKMIPTTTKNNYSPTAAGTERRKEDTPTSSRTLTYYTSTSSRQIVKKY 166
T + P T PTTT + T T TPT ++T T T++ +
Sbjct: 3444 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-----TPTGTQTPTTTPITTTTTVTP-- 3496
Query: 167 TPTPRG-EMKSYSPTQVREKVKYTPSPRGRRVGTYVPSTFMTMETSHAITPRTTVKDSDI 225
TPTP G + + +P V TP+P G + T P T T+ +TP T +
Sbjct: 3497 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPTGTQT 3551
Query: 226 TATYKILETNSLKRIMEETTPTTLKGMFDSTPTFLTHEVEANVLTSPRSVMEKNNLFPPR 285
T I T + + TPT + TPT V +P + P
Sbjct: 3552 PTTTPITTTTT---VTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3603
Query: 286 RVESNSSAHPWGLVGKSNPKTPQGTVL-LHTPATSEGQVTIS-TMTGSSPAETKAFTAAW 343
+ + P TP GT TP T+ VT + T TG+ T T
Sbjct: 3604 TTTTTVTPTP----------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3653
Query: 344 SLRNPSPRTSVSAIKTAPAIVWRLAKKPSTAPSTSTTPTVRAKLTMQVHHCVVVKPTPAM 403
++ P+P + + T I P+ P+ + TPT T + V PTP
Sbjct: 3654 TV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT-----TTPITTTTTVTPTPTP 3707
Query: 404 LTTPSPSLTTALLPEELSPSPSVLPPSLPDLHP 436
T +P+ T ++P+P+ P P
Sbjct: 3708 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3740
Score = 68.2 bits (165), Expect = 4e-11
Identities = 81/333 (24%), Positives = 121/333 (36%), Gaps = 39/333 (11%)
Query: 107 TVENIPSMPKRTAKMIPTTTKNNYSPTAAGTERRKEDTPTSSRTLTYYTSTSSRQIVKKY 166
T + P T PTTT + T T TPT ++T T T++ +
Sbjct: 3467 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-----TPTGTQTPTTTPITTTTTVTP-- 3519
Query: 167 TPTPRG-EMKSYSPTQVREKVKYTPSPRGRRVGTYVPSTFMTMETSHAITPRTTVKDSDI 225
TPTP G + + +P V TP+P G + T P T T+ +TP T +
Sbjct: 3520 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPTGTQT 3574
Query: 226 TATYKILETNSLKRIMEETTPTTLKGMFDSTPTFLTHEVEANVLTSPRSVMEKNNLFPPR 285
T I T + + TPT + TPT V +P + P
Sbjct: 3575 PTTTPITTTTT---VTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3626
Query: 286 RVESNSSAHPWGLVGKSNPKTPQGTVL-LHTPATSEGQVTIS-TMTGSSPAETKAFTAAW 343
+ + P TP GT TP T+ VT + T TG+ T T
Sbjct: 3627 TTTTTVTPTP----------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3676
Query: 344 SLRNPSPRTSVSAIKTAPAIVWRLAKKPSTAPSTSTTPTVRAKLTMQVHHCVVVKPTPAM 403
++ P+P + + T I P+ P+ + TPT T + V PTP
Sbjct: 3677 TV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT-----TTPITTTTTVTPTPTP 3730
Query: 404 LTTPSPSLTTALLPEELSPSPSVLPPSLPDLHP 436
T +P+ T ++P+P+ P P
Sbjct: 3731 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3763
Score = 68.2 bits (165), Expect = 4e-11
Identities = 81/333 (24%), Positives = 121/333 (36%), Gaps = 39/333 (11%)
Query: 107 TVENIPSMPKRTAKMIPTTTKNNYSPTAAGTERRKEDTPTSSRTLTYYTSTSSRQIVKKY 166
T + P T PTTT + T T TPT ++T T T++ +
Sbjct: 3490 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-----TPTGTQTPTTTPITTTTTVTP-- 3542
Query: 167 TPTPRG-EMKSYSPTQVREKVKYTPSPRGRRVGTYVPSTFMTMETSHAITPRTTVKDSDI 225
TPTP G + + +P V TP+P G + T P T T+ +TP T +
Sbjct: 3543 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPTGTQT 3597
Query: 226 TATYKILETNSLKRIMEETTPTTLKGMFDSTPTFLTHEVEANVLTSPRSVMEKNNLFPPR 285
T I T + + TPT + TPT V +P + P
Sbjct: 3598 PTTTPITTTTT---VTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3649
Query: 286 RVESNSSAHPWGLVGKSNPKTPQGTVL-LHTPATSEGQVTIS-TMTGSSPAETKAFTAAW 343
+ + P TP GT TP T+ VT + T TG+ T T
Sbjct: 3650 TTTTTVTPTP----------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3699
Query: 344 SLRNPSPRTSVSAIKTAPAIVWRLAKKPSTAPSTSTTPTVRAKLTMQVHHCVVVKPTPAM 403
++ P+P + + T I P+ P+ + TPT T + V PTP
Sbjct: 3700 TV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT-----TTPITTTTTVTPTPTP 3753
Query: 404 LTTPSPSLTTALLPEELSPSPSVLPPSLPDLHP 436
T +P+ T ++P+P+ P P
Sbjct: 3754 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3786
Score = 68.2 bits (165), Expect = 4e-11
Identities = 81/333 (24%), Positives = 121/333 (36%), Gaps = 39/333 (11%)
Query: 107 TVENIPSMPKRTAKMIPTTTKNNYSPTAAGTERRKEDTPTSSRTLTYYTSTSSRQIVKKY 166
T + P T PTTT + T T TPT ++T T T++ +
Sbjct: 3513 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-----TPTGTQTPTTTPITTTTTVTP-- 3565
Query: 167 TPTPRG-EMKSYSPTQVREKVKYTPSPRGRRVGTYVPSTFMTMETSHAITPRTTVKDSDI 225
TPTP G + + +P V TP+P G + T P T T+ +TP T +
Sbjct: 3566 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPTGTQT 3620
Query: 226 TATYKILETNSLKRIMEETTPTTLKGMFDSTPTFLTHEVEANVLTSPRSVMEKNNLFPPR 285
T I T + + TPT + TPT V +P + P
Sbjct: 3621 PTTTPITTTTT---VTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3672
Query: 286 RVESNSSAHPWGLVGKSNPKTPQGTVL-LHTPATSEGQVTIS-TMTGSSPAETKAFTAAW 343
+ + P TP GT TP T+ VT + T TG+ T T
Sbjct: 3673 TTTTTVTPTP----------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3722
Query: 344 SLRNPSPRTSVSAIKTAPAIVWRLAKKPSTAPSTSTTPTVRAKLTMQVHHCVVVKPTPAM 403
++ P+P + + T I P+ P+ + TPT T + V PTP
Sbjct: 3723 TV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT-----TTPITTTTTVTPTPTP 3776
Query: 404 LTTPSPSLTTALLPEELSPSPSVLPPSLPDLHP 436
T +P+ T ++P+P+ P P
Sbjct: 3777 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3809
Score = 68.2 bits (165), Expect = 4e-11
Identities = 81/333 (24%), Positives = 121/333 (36%), Gaps = 39/333 (11%)
Query: 107 TVENIPSMPKRTAKMIPTTTKNNYSPTAAGTERRKEDTPTSSRTLTYYTSTSSRQIVKKY 166
T + P T PTTT + T T TPT ++T T T++ +
Sbjct: 3536 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-----TPTGTQTPTTTPITTTTTVTP-- 3588
Query: 167 TPTPRG-EMKSYSPTQVREKVKYTPSPRGRRVGTYVPSTFMTMETSHAITPRTTVKDSDI 225
TPTP G + + +P V TP+P G + T P T T+ +TP T +
Sbjct: 3589 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPTGTQT 3643
Query: 226 TATYKILETNSLKRIMEETTPTTLKGMFDSTPTFLTHEVEANVLTSPRSVMEKNNLFPPR 285
T I T + + TPT + TPT V +P + P
Sbjct: 3644 PTTTPITTTTT---VTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3695
Query: 286 RVESNSSAHPWGLVGKSNPKTPQGTVL-LHTPATSEGQVTIS-TMTGSSPAETKAFTAAW 343
+ + P TP GT TP T+ VT + T TG+ T T
Sbjct: 3696 TTTTTVTPTP----------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3745
Query: 344 SLRNPSPRTSVSAIKTAPAIVWRLAKKPSTAPSTSTTPTVRAKLTMQVHHCVVVKPTPAM 403
++ P+P + + T I P+ P+ + TPT T + V PTP
Sbjct: 3746 TV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT-----TTPITTTTTVTPTPTP 3799
Query: 404 LTTPSPSLTTALLPEELSPSPSVLPPSLPDLHP 436
T +P+ T ++P+P+ P P
Sbjct: 3800 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3832
Score = 68.2 bits (165), Expect = 4e-11
Identities = 81/333 (24%), Positives = 121/333 (36%), Gaps = 39/333 (11%)
Query: 107 TVENIPSMPKRTAKMIPTTTKNNYSPTAAGTERRKEDTPTSSRTLTYYTSTSSRQIVKKY 166
T + P T PTTT + T T TPT ++T T T++ +
Sbjct: 3559 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-----TPTGTQTPTTTPITTTTTVTP-- 3611
Query: 167 TPTPRG-EMKSYSPTQVREKVKYTPSPRGRRVGTYVPSTFMTMETSHAITPRTTVKDSDI 225
TPTP G + + +P V TP+P G + T P T T+ +TP T +
Sbjct: 3612 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPTGTQT 3666
Query: 226 TATYKILETNSLKRIMEETTPTTLKGMFDSTPTFLTHEVEANVLTSPRSVMEKNNLFPPR 285
T I T + + TPT + TPT V +P + P
Sbjct: 3667 PTTTPITTTTT---VTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3718
Query: 286 RVESNSSAHPWGLVGKSNPKTPQGTVL-LHTPATSEGQVTIS-TMTGSSPAETKAFTAAW 343
+ + P TP GT TP T+ VT + T TG+ T T
Sbjct: 3719 TTTTTVTPTP----------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3768
Query: 344 SLRNPSPRTSVSAIKTAPAIVWRLAKKPSTAPSTSTTPTVRAKLTMQVHHCVVVKPTPAM 403
++ P+P + + T I P+ P+ + TPT T + V PTP
Sbjct: 3769 TV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT-----TTPITTTTTVTPTPTP 3822
Query: 404 LTTPSPSLTTALLPEELSPSPSVLPPSLPDLHP 436
T +P+ T ++P+P+ P P
Sbjct: 3823 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3855
Score = 68.2 bits (165), Expect = 4e-11
Identities = 81/333 (24%), Positives = 121/333 (36%), Gaps = 39/333 (11%)
Query: 107 TVENIPSMPKRTAKMIPTTTKNNYSPTAAGTERRKEDTPTSSRTLTYYTSTSSRQIVKKY 166
T + P T PTTT + T T TPT ++T T T++ +
Sbjct: 3582 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-----TPTGTQTPTTTPITTTTTVTP-- 3634
Query: 167 TPTPRG-EMKSYSPTQVREKVKYTPSPRGRRVGTYVPSTFMTMETSHAITPRTTVKDSDI 225
TPTP G + + +P V TP+P G + T P T T+ +TP T +
Sbjct: 3635 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPTGTQT 3689
Query: 226 TATYKILETNSLKRIMEETTPTTLKGMFDSTPTFLTHEVEANVLTSPRSVMEKNNLFPPR 285
T I T + + TPT + TPT V +P + P
Sbjct: 3690 PTTTPITTTTT---VTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3741
Query: 286 RVESNSSAHPWGLVGKSNPKTPQGTVL-LHTPATSEGQVTIS-TMTGSSPAETKAFTAAW 343
+ + P TP GT TP T+ VT + T TG+ T T
Sbjct: 3742 TTTTTVTPTP----------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3791
Query: 344 SLRNPSPRTSVSAIKTAPAIVWRLAKKPSTAPSTSTTPTVRAKLTMQVHHCVVVKPTPAM 403
++ P+P + + T I P+ P+ + TPT T + V PTP
Sbjct: 3792 TV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT-----TTPITTTTTVTPTPTP 3845
Query: 404 LTTPSPSLTTALLPEELSPSPSVLPPSLPDLHP 436
T +P+ T ++P+P+ P P
Sbjct: 3846 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3878
Score = 68.2 bits (165), Expect = 4e-11
Identities = 81/333 (24%), Positives = 121/333 (36%), Gaps = 39/333 (11%)
Query: 107 TVENIPSMPKRTAKMIPTTTKNNYSPTAAGTERRKEDTPTSSRTLTYYTSTSSRQIVKKY 166
T + P T PTTT + T T TPT ++T T T++ +
Sbjct: 3605 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-----TPTGTQTPTTTPITTTTTVTP-- 3657
Query: 167 TPTPRG-EMKSYSPTQVREKVKYTPSPRGRRVGTYVPSTFMTMETSHAITPRTTVKDSDI 225
TPTP G + + +P V TP+P G + T P T T+ +TP T +
Sbjct: 3658 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPTGTQT 3712
Query: 226 TATYKILETNSLKRIMEETTPTTLKGMFDSTPTFLTHEVEANVLTSPRSVMEKNNLFPPR 285
T I T + + TPT + TPT V +P + P
Sbjct: 3713 PTTTPITTTTT---VTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3764
Query: 286 RVESNSSAHPWGLVGKSNPKTPQGTVL-LHTPATSEGQVTIS-TMTGSSPAETKAFTAAW 343
+ + P TP GT TP T+ VT + T TG+ T T
Sbjct: 3765 TTTTTVTPTP----------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3814
Query: 344 SLRNPSPRTSVSAIKTAPAIVWRLAKKPSTAPSTSTTPTVRAKLTMQVHHCVVVKPTPAM 403
++ P+P + + T I P+ P+ + TPT T + V PTP
Sbjct: 3815 TV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT-----TTPITTTTTVTPTPTP 3868
Query: 404 LTTPSPSLTTALLPEELSPSPSVLPPSLPDLHP 436
T +P+ T ++P+P+ P P
Sbjct: 3869 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3901
Score = 68.2 bits (165), Expect = 4e-11
Identities = 81/333 (24%), Positives = 121/333 (36%), Gaps = 39/333 (11%)
Query: 107 TVENIPSMPKRTAKMIPTTTKNNYSPTAAGTERRKEDTPTSSRTLTYYTSTSSRQIVKKY 166
T + P T PTTT + T T TPT ++T T T++ +
Sbjct: 3628 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-----TPTGTQTPTTTPITTTTTVTP-- 3680
Query: 167 TPTPRG-EMKSYSPTQVREKVKYTPSPRGRRVGTYVPSTFMTMETSHAITPRTTVKDSDI 225
TPTP G + + +P V TP+P G + T P T T+ +TP T +
Sbjct: 3681 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPTGTQT 3735
Query: 226 TATYKILETNSLKRIMEETTPTTLKGMFDSTPTFLTHEVEANVLTSPRSVMEKNNLFPPR 285
T I T + + TPT + TPT V +P + P
Sbjct: 3736 PTTTPITTTTT---VTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3787
Query: 286 RVESNSSAHPWGLVGKSNPKTPQGTVL-LHTPATSEGQVTIS-TMTGSSPAETKAFTAAW 343
+ + P TP GT TP T+ VT + T TG+ T T
Sbjct: 3788 TTTTTVTPTP----------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3837
Query: 344 SLRNPSPRTSVSAIKTAPAIVWRLAKKPSTAPSTSTTPTVRAKLTMQVHHCVVVKPTPAM 403
++ P+P + + T I P+ P+ + TPT T + V PTP
Sbjct: 3838 TV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT-----TTPITTTTTVTPTPTP 3891
Query: 404 LTTPSPSLTTALLPEELSPSPSVLPPSLPDLHP 436
T +P+ T ++P+P+ P P
Sbjct: 3892 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3924
Score = 68.2 bits (165), Expect = 4e-11
Identities = 81/333 (24%), Positives = 121/333 (36%), Gaps = 39/333 (11%)
Query: 107 TVENIPSMPKRTAKMIPTTTKNNYSPTAAGTERRKEDTPTSSRTLTYYTSTSSRQIVKKY 166
T + P T PTTT + T T TPT ++T T T++ +
Sbjct: 3651 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-----TPTGTQTPTTTPITTTTTVTP-- 3703
Query: 167 TPTPRG-EMKSYSPTQVREKVKYTPSPRGRRVGTYVPSTFMTMETSHAITPRTTVKDSDI 225
TPTP G + + +P V TP+P G + T P T T+ +TP T +
Sbjct: 3704 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPTGTQT 3758
Query: 226 TATYKILETNSLKRIMEETTPTTLKGMFDSTPTFLTHEVEANVLTSPRSVMEKNNLFPPR 285
T I T + + TPT + TPT V +P + P
Sbjct: 3759 PTTTPITTTTT---VTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3810
Query: 286 RVESNSSAHPWGLVGKSNPKTPQGTVL-LHTPATSEGQVTIS-TMTGSSPAETKAFTAAW 343
+ + P TP GT TP T+ VT + T TG+ T T
Sbjct: 3811 TTTTTVTPTP----------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3860
Query: 344 SLRNPSPRTSVSAIKTAPAIVWRLAKKPSTAPSTSTTPTVRAKLTMQVHHCVVVKPTPAM 403
++ P+P + + T I P+ P+ + TPT T + V PTP
Sbjct: 3861 TV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT-----TTPITTTTTVTPTPTP 3914
Query: 404 LTTPSPSLTTALLPEELSPSPSVLPPSLPDLHP 436
T +P+ T ++P+P+ P P
Sbjct: 3915 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3947
Score = 68.2 bits (165), Expect = 4e-11
Identities = 81/333 (24%), Positives = 121/333 (36%), Gaps = 39/333 (11%)
Query: 107 TVENIPSMPKRTAKMIPTTTKNNYSPTAAGTERRKEDTPTSSRTLTYYTSTSSRQIVKKY 166
T + P T PTTT + T T TPT ++T T T++ +
Sbjct: 3674 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-----TPTGTQTPTTTPITTTTTVTP-- 3726
Query: 167 TPTPRG-EMKSYSPTQVREKVKYTPSPRGRRVGTYVPSTFMTMETSHAITPRTTVKDSDI 225
TPTP G + + +P V TP+P G + T P T T+ +TP T +
Sbjct: 3727 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPTGTQT 3781
Query: 226 TATYKILETNSLKRIMEETTPTTLKGMFDSTPTFLTHEVEANVLTSPRSVMEKNNLFPPR 285
T I T + + TPT + TPT V +P + P
Sbjct: 3782 PTTTPITTTTT---VTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3833
Query: 286 RVESNSSAHPWGLVGKSNPKTPQGTVL-LHTPATSEGQVTIS-TMTGSSPAETKAFTAAW 343
+ + P TP GT TP T+ VT + T TG+ T T
Sbjct: 3834 TTTTTVTPTP----------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3883
Query: 344 SLRNPSPRTSVSAIKTAPAIVWRLAKKPSTAPSTSTTPTVRAKLTMQVHHCVVVKPTPAM 403
++ P+P + + T I P+ P+ + TPT T + V PTP
Sbjct: 3884 TV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT-----TTPITTTTTVTPTPTP 3937
Query: 404 LTTPSPSLTTALLPEELSPSPSVLPPSLPDLHP 436
T +P+ T ++P+P+ P P
Sbjct: 3938 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3970
Score = 68.2 bits (165), Expect = 4e-11
Identities = 81/333 (24%), Positives = 121/333 (36%), Gaps = 39/333 (11%)
Query: 107 TVENIPSMPKRTAKMIPTTTKNNYSPTAAGTERRKEDTPTSSRTLTYYTSTSSRQIVKKY 166
T + P T PTTT + T T TPT ++T T T++ +
Sbjct: 3697 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-----TPTGTQTPTTTPITTTTTVTP-- 3749
Query: 167 TPTPRG-EMKSYSPTQVREKVKYTPSPRGRRVGTYVPSTFMTMETSHAITPRTTVKDSDI 225
TPTP G + + +P V TP+P G + T P T T+ +TP T +
Sbjct: 3750 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPTGTQT 3804
Query: 226 TATYKILETNSLKRIMEETTPTTLKGMFDSTPTFLTHEVEANVLTSPRSVMEKNNLFPPR 285
T I T + + TPT + TPT V +P + P
Sbjct: 3805 PTTTPITTTTT---VTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3856
Query: 286 RVESNSSAHPWGLVGKSNPKTPQGTVL-LHTPATSEGQVTIS-TMTGSSPAETKAFTAAW 343
+ + P TP GT TP T+ VT + T TG+ T T
Sbjct: 3857 TTTTTVTPTP----------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3906
Query: 344 SLRNPSPRTSVSAIKTAPAIVWRLAKKPSTAPSTSTTPTVRAKLTMQVHHCVVVKPTPAM 403
++ P+P + + T I P+ P+ + TPT T + V PTP
Sbjct: 3907 TV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT-----TTPITTTTTVTPTPTP 3960
Query: 404 LTTPSPSLTTALLPEELSPSPSVLPPSLPDLHP 436
T +P+ T ++P+P+ P P
Sbjct: 3961 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 3993
Score = 68.2 bits (165), Expect = 4e-11
Identities = 81/333 (24%), Positives = 121/333 (36%), Gaps = 39/333 (11%)
Query: 107 TVENIPSMPKRTAKMIPTTTKNNYSPTAAGTERRKEDTPTSSRTLTYYTSTSSRQIVKKY 166
T + P T PTTT + T T TPT ++T T T++ +
Sbjct: 3720 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-----TPTGTQTPTTTPITTTTTVTP-- 3772
Query: 167 TPTPRG-EMKSYSPTQVREKVKYTPSPRGRRVGTYVPSTFMTMETSHAITPRTTVKDSDI 225
TPTP G + + +P V TP+P G + T P T T+ +TP T +
Sbjct: 3773 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPTGTQT 3827
Query: 226 TATYKILETNSLKRIMEETTPTTLKGMFDSTPTFLTHEVEANVLTSPRSVMEKNNLFPPR 285
T I T + + TPT + TPT V +P + P
Sbjct: 3828 PTTTPITTTTT---VTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3879
Query: 286 RVESNSSAHPWGLVGKSNPKTPQGTVL-LHTPATSEGQVTIS-TMTGSSPAETKAFTAAW 343
+ + P TP GT TP T+ VT + T TG+ T T
Sbjct: 3880 TTTTTVTPTP----------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3929
Query: 344 SLRNPSPRTSVSAIKTAPAIVWRLAKKPSTAPSTSTTPTVRAKLTMQVHHCVVVKPTPAM 403
++ P+P + + T I P+ P+ + TPT T + V PTP
Sbjct: 3930 TV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT-----TTPITTTTTVTPTPTP 3983
Query: 404 LTTPSPSLTTALLPEELSPSPSVLPPSLPDLHP 436
T +P+ T ++P+P+ P P
Sbjct: 3984 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 4016
Score = 68.2 bits (165), Expect = 4e-11
Identities = 81/333 (24%), Positives = 121/333 (36%), Gaps = 39/333 (11%)
Query: 107 TVENIPSMPKRTAKMIPTTTKNNYSPTAAGTERRKEDTPTSSRTLTYYTSTSSRQIVKKY 166
T + P T PTTT + T T TPT ++T T T++ +
Sbjct: 3743 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-----TPTGTQTPTTTPITTTTTVTP-- 3795
Query: 167 TPTPRG-EMKSYSPTQVREKVKYTPSPRGRRVGTYVPSTFMTMETSHAITPRTTVKDSDI 225
TPTP G + + +P V TP+P G + T P T T+ +TP T +
Sbjct: 3796 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPTGTQT 3850
Query: 226 TATYKILETNSLKRIMEETTPTTLKGMFDSTPTFLTHEVEANVLTSPRSVMEKNNLFPPR 285
T I T + + TPT + TPT V +P + P
Sbjct: 3851 PTTTPITTTTT---VTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3902
Query: 286 RVESNSSAHPWGLVGKSNPKTPQGTVL-LHTPATSEGQVTIS-TMTGSSPAETKAFTAAW 343
+ + P TP GT TP T+ VT + T TG+ T T
Sbjct: 3903 TTTTTVTPTP----------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3952
Query: 344 SLRNPSPRTSVSAIKTAPAIVWRLAKKPSTAPSTSTTPTVRAKLTMQVHHCVVVKPTPAM 403
++ P+P + + T I P+ P+ + TPT T + V PTP
Sbjct: 3953 TV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT-----TTPITTTTTVTPTPTP 4006
Query: 404 LTTPSPSLTTALLPEELSPSPSVLPPSLPDLHP 436
T +P+ T ++P+P+ P P
Sbjct: 4007 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 4039
Score = 68.2 bits (165), Expect = 4e-11
Identities = 81/333 (24%), Positives = 121/333 (36%), Gaps = 39/333 (11%)
Query: 107 TVENIPSMPKRTAKMIPTTTKNNYSPTAAGTERRKEDTPTSSRTLTYYTSTSSRQIVKKY 166
T + P T PTTT + T T TPT ++T T T++ +
Sbjct: 3766 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-----TPTGTQTPTTTPITTTTTVTP-- 3818
Query: 167 TPTPRG-EMKSYSPTQVREKVKYTPSPRGRRVGTYVPSTFMTMETSHAITPRTTVKDSDI 225
TPTP G + + +P V TP+P G + T P T T+ +TP T +
Sbjct: 3819 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPTGTQT 3873
Query: 226 TATYKILETNSLKRIMEETTPTTLKGMFDSTPTFLTHEVEANVLTSPRSVMEKNNLFPPR 285
T I T + + TPT + TPT V +P + P
Sbjct: 3874 PTTTPITTTTT---VTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3925
Query: 286 RVESNSSAHPWGLVGKSNPKTPQGTVL-LHTPATSEGQVTIS-TMTGSSPAETKAFTAAW 343
+ + P TP GT TP T+ VT + T TG+ T T
Sbjct: 3926 TTTTTVTPTP----------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3975
Query: 344 SLRNPSPRTSVSAIKTAPAIVWRLAKKPSTAPSTSTTPTVRAKLTMQVHHCVVVKPTPAM 403
++ P+P + + T I P+ P+ + TPT T + V PTP
Sbjct: 3976 TV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT-----TTPITTTTTVTPTPTP 4029
Query: 404 LTTPSPSLTTALLPEELSPSPSVLPPSLPDLHP 436
T +P+ T ++P+P+ P P
Sbjct: 4030 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 4062
Score = 68.2 bits (165), Expect = 4e-11
Identities = 81/333 (24%), Positives = 121/333 (36%), Gaps = 39/333 (11%)
Query: 107 TVENIPSMPKRTAKMIPTTTKNNYSPTAAGTERRKEDTPTSSRTLTYYTSTSSRQIVKKY 166
T + P T PTTT + T T TPT ++T T T++ +
Sbjct: 3789 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-----TPTGTQTPTTTPITTTTTVTP-- 3841
Query: 167 TPTPRG-EMKSYSPTQVREKVKYTPSPRGRRVGTYVPSTFMTMETSHAITPRTTVKDSDI 225
TPTP G + + +P V TP+P G + T P T T+ +TP T +
Sbjct: 3842 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPTGTQT 3896
Query: 226 TATYKILETNSLKRIMEETTPTTLKGMFDSTPTFLTHEVEANVLTSPRSVMEKNNLFPPR 285
T I T + + TPT + TPT V +P + P
Sbjct: 3897 PTTTPITTTTT---VTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3948
Query: 286 RVESNSSAHPWGLVGKSNPKTPQGTVL-LHTPATSEGQVTIS-TMTGSSPAETKAFTAAW 343
+ + P TP GT TP T+ VT + T TG+ T T
Sbjct: 3949 TTTTTVTPTP----------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 3998
Query: 344 SLRNPSPRTSVSAIKTAPAIVWRLAKKPSTAPSTSTTPTVRAKLTMQVHHCVVVKPTPAM 403
++ P+P + + T I P+ P+ + TPT T + V PTP
Sbjct: 3999 TV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT-----TTPITTTTTVTPTPTP 4052
Query: 404 LTTPSPSLTTALLPEELSPSPSVLPPSLPDLHP 436
T +P+ T ++P+P+ P P
Sbjct: 4053 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 4085
Score = 68.2 bits (165), Expect = 4e-11
Identities = 81/333 (24%), Positives = 121/333 (36%), Gaps = 39/333 (11%)
Query: 107 TVENIPSMPKRTAKMIPTTTKNNYSPTAAGTERRKEDTPTSSRTLTYYTSTSSRQIVKKY 166
T + P T PTTT + T T TPT ++T T T++ +
Sbjct: 3812 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-----TPTGTQTPTTTPITTTTTVTP-- 3864
Query: 167 TPTPRG-EMKSYSPTQVREKVKYTPSPRGRRVGTYVPSTFMTMETSHAITPRTTVKDSDI 225
TPTP G + + +P V TP+P G + T P T T+ +TP T +
Sbjct: 3865 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPTGTQT 3919
Query: 226 TATYKILETNSLKRIMEETTPTTLKGMFDSTPTFLTHEVEANVLTSPRSVMEKNNLFPPR 285
T I T + + TPT + TPT V +P + P
Sbjct: 3920 PTTTPITTTTT---VTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3971
Query: 286 RVESNSSAHPWGLVGKSNPKTPQGTVL-LHTPATSEGQVTIS-TMTGSSPAETKAFTAAW 343
+ + P TP GT TP T+ VT + T TG+ T T
Sbjct: 3972 TTTTTVTPTP----------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 4021
Query: 344 SLRNPSPRTSVSAIKTAPAIVWRLAKKPSTAPSTSTTPTVRAKLTMQVHHCVVVKPTPAM 403
++ P+P + + T I P+ P+ + TPT T + V PTP
Sbjct: 4022 TV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT-----TTPITTTTTVTPTPTP 4075
Query: 404 LTTPSPSLTTALLPEELSPSPSVLPPSLPDLHP 436
T +P+ T ++P+P+ P P
Sbjct: 4076 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 4108
Score = 68.2 bits (165), Expect = 4e-11
Identities = 81/333 (24%), Positives = 121/333 (36%), Gaps = 39/333 (11%)
Query: 107 TVENIPSMPKRTAKMIPTTTKNNYSPTAAGTERRKEDTPTSSRTLTYYTSTSSRQIVKKY 166
T + P T PTTT + T T TPT ++T T T++ +
Sbjct: 3835 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-----TPTGTQTPTTTPITTTTTVTP-- 3887
Query: 167 TPTPRG-EMKSYSPTQVREKVKYTPSPRGRRVGTYVPSTFMTMETSHAITPRTTVKDSDI 225
TPTP G + + +P V TP+P G + T P T T+ +TP T +
Sbjct: 3888 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPTGTQT 3942
Query: 226 TATYKILETNSLKRIMEETTPTTLKGMFDSTPTFLTHEVEANVLTSPRSVMEKNNLFPPR 285
T I T + + TPT + TPT V +P + P
Sbjct: 3943 PTTTPITTTTT---VTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPI 3994
Query: 286 RVESNSSAHPWGLVGKSNPKTPQGTVL-LHTPATSEGQVTIS-TMTGSSPAETKAFTAAW 343
+ + P TP GT TP T+ VT + T TG+ T T
Sbjct: 3995 TTTTTVTPTP----------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 4044
Query: 344 SLRNPSPRTSVSAIKTAPAIVWRLAKKPSTAPSTSTTPTVRAKLTMQVHHCVVVKPTPAM 403
++ P+P + + T I P+ P+ + TPT T + V PTP
Sbjct: 4045 TV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT-----TTPITTTTTVTPTPTP 4098
Query: 404 LTTPSPSLTTALLPEELSPSPSVLPPSLPDLHP 436
T +P+ T ++P+P+ P P
Sbjct: 4099 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 4131
Score = 68.2 bits (165), Expect = 4e-11
Identities = 81/333 (24%), Positives = 121/333 (36%), Gaps = 39/333 (11%)
Query: 107 TVENIPSMPKRTAKMIPTTTKNNYSPTAAGTERRKEDTPTSSRTLTYYTSTSSRQIVKKY 166
T + P T PTTT + T T TPT ++T T T++ +
Sbjct: 3858 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-----TPTGTQTPTTTPITTTTTVTP-- 3910
Query: 167 TPTPRG-EMKSYSPTQVREKVKYTPSPRGRRVGTYVPSTFMTMETSHAITPRTTVKDSDI 225
TPTP G + + +P V TP+P G + T P T T+ +TP T +
Sbjct: 3911 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPTGTQT 3965
Query: 226 TATYKILETNSLKRIMEETTPTTLKGMFDSTPTFLTHEVEANVLTSPRSVMEKNNLFPPR 285
T I T + + TPT + TPT V +P + P
Sbjct: 3966 PTTTPITTTTT---VTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPI 4017
Query: 286 RVESNSSAHPWGLVGKSNPKTPQGTVL-LHTPATSEGQVTIS-TMTGSSPAETKAFTAAW 343
+ + P TP GT TP T+ VT + T TG+ T T
Sbjct: 4018 TTTTTVTPTP----------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 4067
Query: 344 SLRNPSPRTSVSAIKTAPAIVWRLAKKPSTAPSTSTTPTVRAKLTMQVHHCVVVKPTPAM 403
++ P+P + + T I P+ P+ + TPT T + V PTP
Sbjct: 4068 TV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT-----TTPITTTTTVTPTPTP 4121
Query: 404 LTTPSPSLTTALLPEELSPSPSVLPPSLPDLHP 436
T +P+ T ++P+P+ P P
Sbjct: 4122 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 4154
Score = 68.2 bits (165), Expect = 4e-11
Identities = 81/333 (24%), Positives = 121/333 (36%), Gaps = 39/333 (11%)
Query: 107 TVENIPSMPKRTAKMIPTTTKNNYSPTAAGTERRKEDTPTSSRTLTYYTSTSSRQIVKKY 166
T + P T PTTT + T T TPT ++T T T++ +
Sbjct: 3881 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-----TPTGTQTPTTTPITTTTTVTP-- 3933
Query: 167 TPTPRG-EMKSYSPTQVREKVKYTPSPRGRRVGTYVPSTFMTMETSHAITPRTTVKDSDI 225
TPTP G + + +P V TP+P G + T P T T+ +TP T +
Sbjct: 3934 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPTGTQT 3988
Query: 226 TATYKILETNSLKRIMEETTPTTLKGMFDSTPTFLTHEVEANVLTSPRSVMEKNNLFPPR 285
T I T + + TPT + TPT V +P + P
Sbjct: 3989 PTTTPITTTTT---VTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPI 4040
Query: 286 RVESNSSAHPWGLVGKSNPKTPQGTVL-LHTPATSEGQVTIS-TMTGSSPAETKAFTAAW 343
+ + P TP GT TP T+ VT + T TG+ T T
Sbjct: 4041 TTTTTVTPTP----------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 4090
Query: 344 SLRNPSPRTSVSAIKTAPAIVWRLAKKPSTAPSTSTTPTVRAKLTMQVHHCVVVKPTPAM 403
++ P+P + + T I P+ P+ + TPT T + V PTP
Sbjct: 4091 TV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT-----TTPITTTTTVTPTPTP 4144
Query: 404 LTTPSPSLTTALLPEELSPSPSVLPPSLPDLHP 436
T +P+ T ++P+P+ P P
Sbjct: 4145 TGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTP 4177
Score = 68.2 bits (165), Expect = 4e-11
Identities = 98/361 (27%), Positives = 135/361 (37%), Gaps = 62/361 (17%)
Query: 107 TVENIPSMPKRTAKMIPTTTKNNYSPTAAGTERRKEDTPTSSRTLTYYTSTSSRQIVKKY 166
T + P T PTTT + T T TPT ++T T T++ +
Sbjct: 4088 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-----TPTGTQTPTTTPITTTTTVTP-- 4140
Query: 167 TPTPRG-EMKSYSPTQVREKVKYTPSPRGRRVGTYVPSTFMTMETSHAITPRTTVKDSDI 225
TPTP G + + +P V TP+P G + T P T T T T
Sbjct: 4141 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTGPPTH 4200
Query: 226 TATYKILETNSLKRIMEETTPTTLKGMFDSTPTFLTHEVEANVLTSPRSVMEKNNLFPPR 285
T+T I E + E +TP T + ST + LT E+ L S P
Sbjct: 4201 TSTAPIAELTTSNPPPESSTPQTSR----STSSPLT---ESTTLLSTL----------PP 4243
Query: 286 RVESNSSAHPWGLVGKSNPKTPQGTVLLHT----PATSE---GQVTISTMTGSSPAETKA 338
+E S+A P S P P T HT P+T+ G T T TGSS A T +
Sbjct: 4244 AIEMTSTAPP------STPTAPTTTSGGHTLSPPPSTTTSPPGTPTRGTTTGSSSAPTPS 4297
Query: 339 F-----TAAWSLRNPSPRTSVSAIKT-------APAIVWRLAKKPSTAPSTS-------- 378
T+AW+ P+P ++ S I+T + ++ + AP
Sbjct: 4298 TVQTTTTSAWT-PTPTPLSTPSIIRTTGLRPYPSSVLICCVLNDTYYAPGEEVYNGTYGD 4356
Query: 379 TTPTVRAKLTMQVHHCVVVKP-TPAMLTTPSPSLTTALLPEEL--SPSPSVLPPSLPDLH 435
T V L+ + P TP+ TPS S T P P+P PP PD
Sbjct: 4357 TCYFVNCSLSCTLEFYNWSCPSTPSPTPTPSKSTPTPSKPSSTPSKPTPGTKPPECPDFD 4416
Query: 436 P 436
P
Sbjct: 4417 P 4417
Score = 67.0 bits (162), Expect = 9e-11
Identities = 79/322 (24%), Positives = 119/322 (36%), Gaps = 39/322 (12%)
Query: 107 TVENIPSMPKRTAKMIPTTTKNNYSPTAAGTERRKEDTPTSSRTLTYYTSTSSRQIVKKY 166
T + P T PTTT + T T TPT ++T T T++ +
Sbjct: 3904 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-----TPTGTQTPTTTPITTTTTVTP-- 3956
Query: 167 TPTPRG-EMKSYSPTQVREKVKYTPSPRGRRVGTYVPSTFMTMETSHAITPRTTVKDSDI 225
TPTP G + + +P V TP+P G + T P T T+ +TP T +
Sbjct: 3957 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPTGTQT 4011
Query: 226 TATYKILETNSLKRIMEETTPTTLKGMFDSTPTFLTHEVEANVLTSPRSVMEKNNLFPPR 285
T I T + + TPT + TPT V +P + P
Sbjct: 4012 PTTTPITTTTT---VTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPI 4063
Query: 286 RVESNSSAHPWGLVGKSNPKTPQGTVL-LHTPATSEGQVTIS-TMTGSSPAETKAFTAAW 343
+ + P TP GT TP T+ VT + T TG+ T T
Sbjct: 4064 TTTTTVTPTP----------TPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTT 4113
Query: 344 SLRNPSPRTSVSAIKTAPAIVWRLAKKPSTAPSTSTTPTVRAKLTMQVHHCVVVKPTPAM 403
++ P+P + + T I P+ P+ + TPT T + V PTP
Sbjct: 4114 TV-TPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPT-----TTPITTTTTVTPTPTP 4167
Query: 404 LTTPSPSLTTALLPEELSPSPS 425
T +P+ T ++P+P+
Sbjct: 4168 TGTQTPTTTPITTTTTVTPTPT 4189
Score = 62.0 bits (149), Expect = 3e-09
Identities = 83/323 (25%), Positives = 110/323 (34%), Gaps = 32/323 (9%)
Query: 115 PKRTAKMIPTTTKNNYSPTAAGTERRKEDTPTSSRTLTYY---TSTSSRQIVKKYTPTPR 171
P T + PTTT + PT T TP+ T T T+T S I TP P
Sbjct: 1410 PTSTTTLPPTTTPS--PPTTTTTTPPPTTTPSPPITTTTTPPPTTTPSPPISTTTTPPPT 1467
Query: 172 GEMKSYSPTQVREKVKYTPSPRGRRVGTYVPSTFMTMETSHAITPRTTVKDSDITATYKI 231
PT TPSP T P+T + T+ ITP + T T
Sbjct: 1468 TTPSP--PTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPASTTTLPPTTTPSP 1525
Query: 232 LETNSLKRIMEETTPTTLKGMFDSTPTFLTHEVEANVL---TSPRSVMEKNNLFPPRRVE 288
T + TTP T T +T L T+P PP
Sbjct: 1526 PTTTT-------TTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTP 1578
Query: 289 SNSSAHPWGLVGKSNPKTPQGTVLLHTPATSEGQVTISTMTGSSPAETKAFTAAWSLRNP 348
S + + P P T P T+ T +T T P T + + P
Sbjct: 1579 SPPTT--------TTPSPPTITTTTPPPTTTPSPPTTTTTT-PPPTTTPSPPTTTPITPP 1629
Query: 349 SPRTSVSAIKT-APAIVWRLAKKPSTAPSTSTTPTVRAKLTMQVHHCVVVKPTPAMLTTP 407
+ T++ T +P P+T PS TT T +T P+ + TTP
Sbjct: 1630 TSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTTP 1689
Query: 408 SPSLTTALLPEELSPSPSVLPPS 430
SP TT +PSP+ P S
Sbjct: 1690 SPPTTTM-----TTPSPTTTPSS 1707
Score = 61.6 bits (148), Expect = 4e-09
Identities = 99/396 (25%), Positives = 133/396 (33%), Gaps = 48/396 (12%)
Query: 59 PIKLASRDLSSEEMMMMSSSPSKPSSEMGGKMLVPQASVGSDEATLSMTVE--NIPSMPK 116
P S +S + +++PS P++ P + S T + T PS P
Sbjct: 1402 PTTTPSPPPTSTTTLPPTTTPSPPTTTT---TTPPPTTTPSPPITTTTTPPPTTTPSPPI 1458
Query: 117 RTAKMIPTTTKNNYSPTAAGTERRKEDTPTSSRTLTYYTSTSSRQIVKKYTP-TPRGEMK 175
T P TT + T PT++ T T+T S TP TP
Sbjct: 1459 STTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTT---TPITPPASTT 1515
Query: 176 SYSPTQVREKVKYTPSPRGRRVGTYVPSTFMTMETSHAITPRTTVKDSDITATYKILETN 235
+ PT TPSP T P+T + T+ ITP T+ T T T
Sbjct: 1516 TLPPTT-------TPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTT 1568
Query: 236 SLKRIMEETTPTTLKGMFDSTPTFLTHEVEANVLTSPRSVMEKNNLFPPRRVESNSSAHP 295
+ TTP+ S PT T SP + PP S + P
Sbjct: 1569 TTTP-PPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTP--PPTTTPSPPTTTP 1625
Query: 296 -------WGLVGKSNPKTPQGTVLLHTPATSEGQVTISTMTGSSPAETKAFTAAWSLRNP 348
L + P P T P T+ T T T S P T P
Sbjct: 1626 ITPPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPT--TTTPSPPITTTT--------TP 1675
Query: 349 SPRTSVSA-IKTAPAIVWRLAKKPSTAPSTSTTPTVRAKLTMQVHHCVVVKPTPAMLTTP 407
P T+ S+ I T P+ T PS +TTP+ T P P +TTP
Sbjct: 1676 PPTTTPSSPITTTPSP----PTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTP 1731
Query: 408 SPSLTTA-------LLPEELSPSPSVLPPSLPDLHP 436
SP+ T + LP + SP P P + P
Sbjct: 1732 SPTTTPSPPTTTMTTLPPTTTSSPLTTTPLPPSITP 1767
Score = 60.5 bits (145), Expect = 9e-09
Identities = 80/333 (24%), Positives = 115/333 (34%), Gaps = 30/333 (9%)
Query: 107 TVENIPSMPKRTAKMIPTTTKNNYSPTAAGTERRKEDTPTSSRTLTYYTSTSSRQIVKKY 166
T + P T PTTT + T T TPT ++T T T++ +
Sbjct: 3973 TTTTVTPTPTPTGTQTPTTTPITTTTTVTPTP-----TPTGTQTPTTTPITTTTTVTP-- 4025
Query: 167 TPTPRG-EMKSYSPTQVREKVKYTPSPRGRRVGTYVPSTFMTMETSHAITPRTTVKDSDI 225
TPTP G + + +P V TP+P G + T P T T+ +TP T +
Sbjct: 4026 TPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPIT-----TTTTVTPTPTPTGTQT 4080
Query: 226 TATYKILETNSLKRIMEETTPTTLKGMFDSTPTFLTHEVEANVLTSPRSVMEKNNLFPPR 285
T I T + + TPT + TPT V +P + P
Sbjct: 4081 PTTTPITTTTT---VTPTPTPTGTQ-----TPTTTPITTTTTVTPTPTPTGTQTPTTTPI 4132
Query: 286 RVESNSSAHPWGLVGKSNPKTPQGTVLLHTPATSEGQVTISTMTGSSPAETKAFTAAWSL 345
+ + P ++ TP T TP + T T + T T +
Sbjct: 4133 TTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTGTQTPTTTPITTTTTVTPTPTPTG 4192
Query: 346 RNPSPRTSVSAIKTAPAIVWRLAKKPSTAPSTSTTPTVRAKLTMQVHHCVVVKPTPAMLT 405
P T S TAP + P + + T+ + + LT + P M +
Sbjct: 4193 TQTGPPTHTS---TAPIAELTTSNPPPESSTPQTSRSTSSPLTESTTLLSTLPPAIEMTS 4249
Query: 406 TPSPSLTTALLPEE----LSPSPSVL--PPSLP 432
T PS TA LSP PS PP P
Sbjct: 4250 TAPPSTPTAPTTTSGGHTLSPPPSTTTSPPGTP 4282
Score = 50.4 bits (119), Expect = 9e-06
Identities = 83/332 (25%), Positives = 103/332 (31%), Gaps = 54/332 (16%)
Query: 112 PSMPKRTAKMIPTTTKNNYSPTAAGTERRKEDTPTSSRTLTYYTSTSSRQIVKKYTPTPR 171
PS P T PT+T PT + PT++ T T+T S I TP P
Sbjct: 1399 PSPPTTTPSPPPTST-TTLPPTTTPSP------PTTTTTTPPPTTTPSPPITTTTTPPPT 1451
Query: 172 GEMKSYSPTQVREKVKYTPSPRGRRVGTYVPSTFMTMETSHAITPRTTVKDSDITATYKI 231
TPSP T P+T + T+ P TT T T
Sbjct: 1452 T----------------TPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPP 1495
Query: 232 LETNSLKRIMEETTPTTLKGMFDSTPTFLTHEVEANVLTSPRSVMEKNNLFPPRRVESNS 291
T TTP T + P T T+P + PP
Sbjct: 1496 PTTTPSP---PTTTPITPPASTTTLPPTTTPSPPTTTTTTPPPTTTPS---PPTTTPITP 1549
Query: 292 SAHPWGLVGKSNPKTPQGTVLLHTPATSEGQVTISTMTGSSPAETKAFTAAWSLRNPSPR 351
L + P P T P T+ T T T S P T T PSP
Sbjct: 1550 PTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPT--TTTPSPPTITT--TTPPPTTTPSPP 1605
Query: 352 TSVSAIKTAPAIVWRLAKKPSTAPST-STTPTVRAKLTMQVHHCVVVKPTPAMLTTPSPS 410
T+ + T P P+T PS +TTP T + P P TTP P+
Sbjct: 1606 TTTTT--TPP---------PTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTPPPT 1654
Query: 411 LTTALLPEELSPSPSVLPPSLPDLHPKGEYPP 442
T PSP P + PP
Sbjct: 1655 TT---------PSPPTTTTPSPPITTTTTPPP 1677
Score = 42.4 bits (98), Expect = 0.002
Identities = 30/93 (32%), Positives = 37/93 (39%), Gaps = 5/93 (5%)
Query: 345 LRNPSPRTSVSAIKTAPAIVWRLAKKPSTAPSTSTTPTVRAKLTMQVHHCVVVKPTPAML 404
+ PSP T+ + P P+T PS TT T T + TP
Sbjct: 1396 ITTPSPPTTTPS----PPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPT 1451
Query: 405 TTPSPSL-TTALLPEELSPSPSVLPPSLPDLHP 436
TTPSP + TT P +PSP PS P P
Sbjct: 1452 TTPSPPISTTTTPPPTTTPSPPTTTPSPPTTTP 1484
>gi|4504487 histidine rich calcium binding protein precursor [Homo
sapiens]
Length = 699
Score = 68.6 bits (166), Expect = 3e-11
Identities = 52/169 (30%), Positives = 75/169 (44%), Gaps = 26/169 (15%)
Query: 741 PGGQEDVAEAESTGEMPGE----EGETAGEGETEEKSGGETQPEGEGETETQGKGEECED 796
P +++ AE + P + E G G+ P G + + + +
Sbjct: 423 PREEDEEVSAELGHQAPSHRQSHQDEETGHGQRGSIKEMSHHPPGHTVVKDRSHLRKDDS 482
Query: 797 ENEAEGKGDNEGEDEGEIHAEDGEMKGNEGETESQELSAENHGEAKNDEKGVEDGGGSDG 856
E E E + D +E + +E GE KG + QE DE+ E+G G
Sbjct: 483 EEEKEKEEDPGSHEEDDESSEQGE-KGTHHGSRDQE-----------DEEDEEEGHGLSL 530
Query: 857 GDSEEEEEEEEEQEEEEEEEEQEEEEE----------EEEEEEEKGNEE 895
EEEEE++EE+EEEE+EE +EE E EEEEEEE+G EE
Sbjct: 531 NQEEEEEEDKEEEEEEEDEERREERAEVGAPLSPDHSEEEEEEEEGLEE 579
Score = 57.8 bits (138), Expect = 6e-08
Identities = 60/242 (24%), Positives = 100/242 (41%), Gaps = 42/242 (17%)
Query: 690 EKEEESLN-----QGARAQPQAKAESKPEEEEPAKLPAVTVTPAPVPDIKGDQKENPGGQ 744
E+E+E ++ QG + + + EEEE +T + Q
Sbjct: 351 EEEDEDVSTERWHQGPQHVHHGLVDEEEEEEE--------ITVQFGHYVASHQPRGHKSD 402
Query: 745 EDVAEAESTGEMPGEEGETAGEGETEEKSGGETQPEGEGETETQGKGEECEDENEAEGKG 804
E+ + E E+P E EE S E Q ++E G G
Sbjct: 403 EEDFQDEYKTEVPHHHHHRVPREEDEEVSA---------ELGHQAPSHRQSHQDEETGHG 453
Query: 805 DNEGEDEGEIHA-------EDGEMKGNEGETESQELSAENHGEAKNDEKGVEDGG-GSDG 856
E H + ++ ++ E E ++ E+ G + D++ E G G+
Sbjct: 454 QRGSIKEMSHHPPGHTVVKDRSHLRKDDSEEEKEK--EEDPGSHEEDDESSEQGEKGTHH 511
Query: 857 GDSEEEEEEEEEQEE----EEEEEEQEEEEEEEEEEEEKGNEE------PLSLDWPETRQ 906
G ++E+EE+EE+ +EEEE+E++EEEEEEE+E+ EE PLS D E +
Sbjct: 512 GSRDQEDEEDEEEGHGLSLNQEEEEEEDKEEEEEEEDEERREERAEVGAPLSPDHSEEEE 571
Query: 907 KQ 908
++
Sbjct: 572 EE 573
Score = 54.3 bits (129), Expect = 6e-07
Identities = 57/210 (27%), Positives = 87/210 (41%), Gaps = 33/210 (15%)
Query: 718 AKLPAVTVTPAPVPDIKGD-----QKENPGGQEDVAEAESTGEM------PGEEGETAGE 766
A + ++ + PA ++GD + N G ++E E++ E+ P + + +
Sbjct: 15 AGVASLLLPPAMTQQLRGDGLGFRNRNNSTGVAGLSE-EASAELRHHLHSPRDHPDENKD 73
Query: 767 GETEEKSGGETQPEGEGETETQGK--GEECEDENEAEGKGDNEGEDEGEIHAEDG-EMKG 823
TE + P+ E E E K G + K +EG E+ AE G + +G
Sbjct: 74 VSTENGHHFWSHPDREKEDEDVSKEYGHLLPGHRSQDHKVGDEGVSGEEVFAEHGGQARG 133
Query: 824 NEGE-TESQELSAEN---------HGEAKNDEKGVEDGG--------GSDGGDSEEEEEE 865
+ G +E E SAE+ H DE V G G D E++E E
Sbjct: 134 HRGHGSEDTEDSAEHRHHLPSHRSHSHQDEDEDEVVSSEHHHHILRHGHRGHDGEDDEGE 193
Query: 866 EEEQEEEEEEEEQEEEEEEEEEEEEKGNEE 895
EEE+EEEEEEE E + G+EE
Sbjct: 194 EEEEEEEEEEEASTEYGHQAHRHRGHGSEE 223
Score = 50.1 bits (118), Expect = 1e-05
Identities = 54/236 (22%), Positives = 87/236 (36%), Gaps = 52/236 (22%)
Query: 686 RLAKEKEEESLNQGARAQPQAKAESKPEEEEPAKLPAVTVTPAPVPDIKGDQKENPGGQE 745
R+ +E++EE + P + + EE + ++ P + + ++
Sbjct: 421 RVPREEDEEVSAELGHQAPSHRQSHQDEETGHGQRGSIKEMSHHPPGHTVVKDRSHLRKD 480
Query: 746 DVAEAESTGEMPG---EEGETAGEGETEEKSGGETQPEGEGETETQGKGEECEDENEAEG 802
D E + E PG E+ E++ +GE G Q + E E E G E+E E +
Sbjct: 481 DSEEEKEKEEDPGSHEEDDESSEQGEKGTHHGSRDQEDEEDEEEGHGLSLNQEEEEEEDK 540
Query: 803 KGDNEGEDEGEIHAEDGEMKGNEGETESQELSAENHGEAKNDEKGVEDGGGSDGGDSEEE 862
+ + E EDE + E+ E G SEEE
Sbjct: 541 EEEEEEEDE------------------------------ERREERAEVGAPLSPDHSEEE 570
Query: 863 EEEEEEQEEEE-------------------EEEEQEEEEEEEEEEEEKGNEEPLSL 899
EEEEE EE+E EE+ E+ ++ +E GN +P SL
Sbjct: 571 EEEEEGLEEDEPRFTIIPNPLDRREEAGGASSEEESGEDTGPQDAQEYGNYQPGSL 626
Score = 48.9 bits (115), Expect = 3e-05
Identities = 49/187 (26%), Positives = 70/187 (37%), Gaps = 21/187 (11%)
Query: 714 EEEPAKLPAVTVTPAPVPDIKGDQKENPGG---------QEDVAEAESTGEM-PGEEGET 763
EE A+L +P PD D G +ED ++ G + PG +
Sbjct: 51 EEASAELRHHLHSPRDHPDENKDVSTENGHHFWSHPDREKEDEDVSKEYGHLLPGHRSQD 110
Query: 764 AGEGETEEKSGGETQPEGEGETETQGKGEECEDENEAEGKGDNEGEDEGEIHAEDGEMKG 823
G+ E SG E E G Q +G + G D E E H
Sbjct: 111 HKVGD-EGVSGEEVFAEHGG----QARG------HRGHGSEDTEDSAEHRHHLPSHRSHS 159
Query: 824 NEGETESQELSAENHGEAKNDEKGVEDGGGSDGGDSEEEEEEEEEQEEEEEEEEQEEEEE 883
++ E E + +S+E+H DG +G + EEEEEEEEE E +
Sbjct: 160 HQDEDEDEVVSSEHHHHILRHGHRGHDGEDDEGEEEEEEEEEEEEASTEYGHQAHRHRGH 219
Query: 884 EEEEEEE 890
EE+E+
Sbjct: 220 GSEEDED 226
Score = 45.4 bits (106), Expect = 3e-04
Identities = 31/149 (20%), Positives = 62/149 (41%), Gaps = 25/149 (16%)
Query: 758 GEEGETAGEGETEEKSGGETQPEGEGETETQGKGE-------------ECEDENEA---- 800
G+EG +GE E G G G +T+ E + EDE+E
Sbjct: 114 GDEG-VSGEEVFAEHGGQARGHRGHGSEDTEDSAEHRHHLPSHRSHSHQDEDEDEVVSSE 172
Query: 801 -------EGKGDNEGEDEGEIHAEDGEMKGNEGETESQELSAENHGEAKNDEKGVEDGGG 853
G ++GED+ E+ E + E TE + + G +++ V DG
Sbjct: 173 HHHHILRHGHRGHDGEDDEGEEEEEEEEEEEEASTEYGHQAHRHRGHGSEEDEDVSDGHH 232
Query: 854 SDGGDSEEEEEEEEEQEEEEEEEEQEEEE 882
G + EE++ ++++++++ ++++
Sbjct: 233 HHGPSHRHQGHEEDDDDDDDDDDDDDDDD 261
Score = 39.7 bits (91), Expect = 0.016
Identities = 32/110 (29%), Positives = 48/110 (43%), Gaps = 5/110 (4%)
Query: 689 KEKEEE----SLNQGARAQPQAKAESKPEEEEPAKLPAVTVTPAPVPDIKGDQKENPGGQ 744
+E EEE SLNQ + + E + E+EE + A P PD +++E G
Sbjct: 519 EEDEEEGHGLSLNQEEEEEEDKEEEEEEEDEERREERAEVGAPLS-PDHSEEEEEEEEGL 577
Query: 745 EDVAEAESTGEMPGEEGETAGEGETEEKSGGETQPEGEGETETQGKGEEC 794
E+ + P + E AG +EE+SG +T P+ E G C
Sbjct: 578 EEDEPRFTIIPNPLDRREEAGGASSEEESGEDTGPQDAQEYGNYQPGSLC 627
Score = 39.3 bits (90), Expect = 0.021
Identities = 39/182 (21%), Positives = 69/182 (37%), Gaps = 25/182 (13%)
Query: 734 KGDQKENPGGQEDVAEAESTGEMPGEEGETA------GEGETEEKSGGETQPEGEGETET 787
+G E+ G+E+ E E E E G A G E E+ S G G +
Sbjct: 183 RGHDGEDDEGEEEEEEEEEEEEASTEYGHQAHRHRGHGSEEDEDVSDGHHH---HGPSHR 239
Query: 788 QGKGEECEDENEAEGKGDNEGEDEGEIHAEDGEMKGNEGETESQELSA-----------E 836
+G E +D+++ + D++ +D + G E +++S
Sbjct: 240 H-QGHEEDDDDDDDDDDDDDDDDVSIEYRHQAHRHQGHGIEEDEDVSDGHHHRDPSHRHR 298
Query: 837 NHGEAKNDEKGVEDGGGSDGGDSEEEEEEEEEQEEEEEE----EEQEEEEEEEEEEEEKG 892
+H E ND+ V G ++ +EE E E + + + +EEE+E+
Sbjct: 299 SHEEDDNDDDDVSTEYGHQAHRHQDHRKEEVEAVSGEHHHHVPDHRHQGHRDEEEDEDVS 358
Query: 893 NE 894
E
Sbjct: 359 TE 360
>gi|100816397 MYST histone acetyltransferase (monocytic leukemia) 4
[Homo sapiens]
Length = 2073
Score = 67.0 bits (162), Expect = 9e-11
Identities = 41/121 (33%), Positives = 59/121 (48%), Gaps = 5/121 (4%)
Query: 795 EDENEAEGKGDNEGEDEGEIHAEDGEMKGNEGETESQELSAEN-----HGEAKNDEKGVE 849
E+E EAE + + E E+ E+ + ++ H G
Sbjct: 999 EEEREAEKEAERLMEQASCWEKEEQEILSTRANSRQSPAKVQSKNKYLHSPESRPVTGER 1058
Query: 850 DGGGSDGGDSEEEEEEEEEQEEEEEEEEQEEEEEEEEEEEEKGNEEPLSLDWPETRQKQA 909
+S EEEEEEE++EEEEEEEE+EE+EEEEEEEEE+ EE + P + Q+
Sbjct: 1059 GQLLELSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQSSPPRLTKPQS 1118
Query: 910 I 910
+
Sbjct: 1119 V 1119
Score = 63.5 bits (153), Expect = 1e-09
Identities = 76/328 (23%), Positives = 135/328 (41%), Gaps = 49/328 (14%)
Query: 628 LSKPGDGAI------AVDELQDNKKLKLPSLLTRG--SSSTSLHNSTIRSTIYQLMLHSL 679
L+KP AI + + + K+ ++ S +T S +T + N ++ + + L
Sbjct: 1113 LTKPQSVAIKRKRPFVLKKKRGRKRRRINSSVTTETISETTEVLNEPFDNSDEERPMPQL 1172
Query: 680 DPLREVRLAKEKEEESLNQGARAQPQAKAESKPEEEEPAKL-----PAVTVTPAPVPDIK 734
+P E+ + ++ + L + + QP K +++ EE + P ++K
Sbjct: 1173 EPTCEIEVEEDGRKPVLRKAFQHQPGKKRQTEEEEGKDNHCFKNADPCRNNMNDDSSNLK 1232
Query: 735 GDQKENP-----------GGQEDVAE-----AESTG---------EMPGEEGETAGEGET 769
K+NP G + +++ TG E P E E E
Sbjct: 1233 EGSKDNPEPLKCKQVWPKGTKRGLSKWRQNKERKTGFKLNLYTPPETPMEPDEQVTVEEQ 1292
Query: 770 EEKSGGETQPEG---EGETETQGKGEECEDENEAEGKGDNEGEDEGEIHAEDGEMKGNEG 826
+E S G+T P E E + G+ ++EN E + + ++ E
Sbjct: 1293 KETSEGKTSPSPIRIEEEVKETGEALLPQEENRREETCAPVSPNTSPGEKPEDDLIKPEE 1352
Query: 827 ETESQELSAENHGEAKNDEKGVEDGGGS-----DGGDSEEEEEEEEEQEEEEEEEEQEEE 881
E E +E E E + +E E+GGG+ DG S+E+EE E E+E+ + E
Sbjct: 1353 EEEEEEEEEEEEEEEEGEE---EEGGGNVEKDPDGAKSQEKEEPEISTEKEDSARLDDHE 1409
Query: 882 EEEEEEEEEKGNEEPLSLDWPETRQKQA 909
EEEEE+EE NE+ + D ++ + A
Sbjct: 1410 EEEEEDEEPSHNEDHDADDEDDSHMESA 1437
Score = 58.2 bits (139), Expect = 4e-08
Identities = 65/284 (22%), Positives = 118/284 (41%), Gaps = 41/284 (14%)
Query: 668 RSTIYQLMLHS-----LDPLREVRLAKEKEE---ESLNQGARAQPQAKAESK---PEEEE 716
R T ++L L++ ++P +V + ++KE ++ R + + K + P+EE
Sbjct: 1265 RKTGFKLNLYTPPETPMEPDEQVTVEEQKETSEGKTSPSPIRIEEEVKETGEALLPQEEN 1324
Query: 717 PAKLPAVTVTPAPVPDIKGDQ---KENPGGQEDVAEAESTGEMPGEEGETAGEGE----- 768
+ V+P P K + K +E+ E E E GEE E G E
Sbjct: 1325 RREETCAPVSPNTSPGEKPEDDLIKPEEEEEEEEEEEEEEEEEEGEEEEGGGNVEKDPDG 1384
Query: 769 --TEEKSGGETQPEGEGETETQGKGEECEDENEAEGKGDNEGEDEGEIHAEDGEMKGNEG 826
++EK E E E EE E++ E D++ +DE + H E E++ E
Sbjct: 1385 AKSQEKEEPEISTEKEDSARLDDHEEEEEEDEEPSHNEDHDADDEDDSHMESAEVEKEEL 1444
Query: 827 ETESQELSAENH----------GEAKND---EKGVEDGGGSDG------GDSEEEEEEEE 867
ES + EN G + + + GV+ + GD E E +E
Sbjct: 1445 PRESFKEVLENQETFLDLNVQPGHSNPEVLMDCGVDLTASCNSEPKELAGDPEAVPESDE 1504
Query: 868 EQEEEEEEEEQEEEEEEEEEEE-EKGNEEPLSLDWPETRQKQAI 910
E E+ ++Q+++ +E + E ++GN + +D + Q++
Sbjct: 1505 EPPPGEQAQKQDQKNSKEVDTEFKEGNPATMEIDSETVQAVQSL 1548
Score = 56.2 bits (134), Expect = 2e-07
Identities = 51/187 (27%), Positives = 78/187 (41%), Gaps = 23/187 (12%)
Query: 736 DQKENPGGQEDVA------EAESTGE--MPGEEGETAGEGETEEKSGGETQPEGEGETET 787
+QKE G+ + E + TGE +P EE ET T P + E +
Sbjct: 1291 EQKETSEGKTSPSPIRIEEEVKETGEALLPQEENRRE---ETCAPVSPNTSPGEKPEDDL 1347
Query: 788 QGKGEECEDENEAEGKGDNEGEDEGEIHAEDGEMKGNEGETESQELSAENHGEAKNDEKG 847
EE E+E E E + E E+EGE G ++ + +SQE K D
Sbjct: 1348 IKPEEEEEEEEEEE---EEEEEEEGEEEEGGGNVEKDPDGAKSQEKEEPEISTEKEDSAR 1404
Query: 848 VEDGGGSDGGDSEEEEEEEEEQEEEEEEEEQEEEEEEEEEEEEKGNEEPLSLDWPETRQK 907
++D EEEEEE+E+ E+ + ++E++ E E EE + E +
Sbjct: 1405 LDD---------HEEEEEEDEEPSHNEDHDADDEDDSHMESAEVEKEELPRESFKEVLEN 1455
Query: 908 QAIYLFL 914
Q +L L
Sbjct: 1456 QETFLDL 1462
Score = 40.8 bits (94), Expect = 0.007
Identities = 34/143 (23%), Positives = 62/143 (43%), Gaps = 9/143 (6%)
Query: 776 ETQPEGEGETETQGKGEECEDENEAE--GKGDNEGEDEGEIHAEDGEMKGNEGET----- 828
E + E E E E + C ++ E E N + ++ +++ + E
Sbjct: 999 EEEREAEKEAERLMEQASCWEKEEQEILSTRANSRQSPAKVQSKNKYLHSPESRPVTGER 1058
Query: 829 -ESQELSAENHGEAKNDEKGVEDGGGSDGGDSEEEEEEEEEQEEEEEEEEQEEEEEEEEE 887
+ ELS E+ E + +E+ E+ + + +EEEEEEEE+EEEEE + + +
Sbjct: 1059 GQLLELSKES-SEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQSSPPRLTKPQ 1117
Query: 888 EEEKGNEEPLSLDWPETRQKQAI 910
+ P L R+++ I
Sbjct: 1118 SVAIKRKRPFVLKKKRGRKRRRI 1140
Score = 37.4 bits (85), Expect = 0.079
Identities = 75/315 (23%), Positives = 109/315 (34%), Gaps = 94/315 (29%)
Query: 673 QLMLHSLDPLREVRLAKEKEEESLNQGARAQPQAKAESKPEEEEP--AKLPAVTVTPAPV 730
QL+ S + E +++EEE + + + E + EEEE P P V
Sbjct: 1060 QLLELSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQSSPPRLTKPQSV 1119
Query: 731 PDIKGDQ----KENPGGQEDVAEAESTGEMPGEEGETAGE---GETEEKSGGETQPEGEG 783
IK + K+ G + + T E E E E EE+ + +P E
Sbjct: 1120 A-IKRKRPFVLKKKRGRKRRRINSSVTTETISETTEVLNEPFDNSDEERPMPQLEPTCEI 1178
Query: 784 ETETQGK------------GEECEDENEAEGKGDN--EGEDEGEIHAEDGEMKGNEGETE 829
E E G+ G++ + E E EGK ++ + D + D EG +
Sbjct: 1179 EVEEDGRKPVLRKAFQHQPGKKRQTEEE-EGKDNHCFKNADPCRNNMNDDSSNLKEGSKD 1237
Query: 830 SQELSAENHGEAKNDEKGV----------------------------------EDGGGSD 855
+ E K ++G+ E S+
Sbjct: 1238 NPEPLKCKQVWPKGTKRGLSKWRQNKERKTGFKLNLYTPPETPMEPDEQVTVEEQKETSE 1297
Query: 856 GGDS------EEEEEE-------EEEQEEEE----------------------EEEEQEE 880
G S EEE +E +EE EE EEEE+EE
Sbjct: 1298 GKTSPSPIRIEEEVKETGEALLPQEENRREETCAPVSPNTSPGEKPEDDLIKPEEEEEEE 1357
Query: 881 EEEEEEEEEEKGNEE 895
EEEEEEEEEE+G EE
Sbjct: 1358 EEEEEEEEEEEGEEE 1372
Score = 35.4 bits (80), Expect = 0.30
Identities = 30/127 (23%), Positives = 51/127 (40%), Gaps = 17/127 (13%)
Query: 690 EKEEESLNQGARAQPQAKAESKPEEEEPAKLPAVTVTPAPVPDIKGDQKENPGGQEDVAE 749
E+E E+ + R QA K E+E + + + +++P V
Sbjct: 999 EEEREAEKEAERLMEQASCWEKEEQE--------------ILSTRANSRQSPA---KVQS 1041
Query: 750 AESTGEMPGEEGETAGEGETEEKSGGETQPEGEGETETQGKGEECEDENEAEGKGDNEGE 809
P T G+ E S ++ E E E E + + EE E+E+E E + + E E
Sbjct: 1042 KNKYLHSPESRPVTGERGQLLELSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEE 1101
Query: 810 DEGEIHA 816
+E I +
Sbjct: 1102 EEENIQS 1108
Score = 31.2 bits (69), Expect = 5.6
Identities = 24/92 (26%), Positives = 39/92 (42%), Gaps = 2/92 (2%)
Query: 690 EKEEESL--NQGARAQPQAKAESKPEEEEPAKLPAVTVTPAPVPDIKGDQKENPGGQEDV 747
EKEE+ + + Q AK +SK + + VT + ++ + E +ED
Sbjct: 1019 EKEEQEILSTRANSRQSPAKVQSKNKYLHSPESRPVTGERGQLLELSKESSEEEEEEEDE 1078
Query: 748 AEAESTGEMPGEEGETAGEGETEEKSGGETQP 779
E E E +E E E E EE+ ++ P
Sbjct: 1079 EEEEEEEEEEEDEEEEEEEEEEEEEENIQSSP 1110
>gi|24415404 MDN1, midasin homolog [Homo sapiens]
Length = 5596
Score = 67.0 bits (162), Expect = 9e-11
Identities = 52/154 (33%), Positives = 79/154 (51%), Gaps = 22/154 (14%)
Query: 745 EDVAEAESTGEMPGEEGETAGEGE----TEEKSGGETQPEGEGETETQGKGEECEDENEA 800
ED A E E EG GEGE ++ G E Q E +T KG+E +D+ +
Sbjct: 4662 EDSA-GEGATEFHDYEGGGIGEGEGMKDVSDQIGNEEQVE-----DTFQKGQE-KDKEDP 4714
Query: 801 EGKGDNEGEDEGEIHAEDGEMKGNEGETESQELSAENHGEAKNDEKGVEDGGGSDG--GD 858
+ K D +GED +ED + K ++GE E QE ++DEK +GG D GD
Sbjct: 4715 DSKSDIKGEDNAIEMSEDFDGKMHDGELEEQE---------EDDEKSDSEGGDLDKHMGD 4765
Query: 859 SEEEEEEEEEQEEEEEEEEQEEEEEEEEEEEEKG 892
EE ++ ++ +++E+E+EEEE+ + EE G
Sbjct: 4766 LNGEEADKLDERLWGDDDEEEDEEEEDNKTEETG 4799
Score = 65.1 bits (157), Expect = 4e-10
Identities = 49/195 (25%), Positives = 87/195 (44%), Gaps = 12/195 (6%)
Query: 693 EESLNQGARAQPQAKAESKPEEEEPAKLPAVTVTPAPVPDIKGDQKENPGGQEDVAEAES 752
E+ +N+ + + E P K+P P D+ D ++ GG E
Sbjct: 4846 EDKINEQIDERDYDENEVDPYHGNQEKVPEPEALDLP-DDLNLDSEDKNGG-------ED 4897
Query: 753 TGEMPGEEGETAGEGETEEKSGGETQPEGEGETETQGKGEECEDENEAEGKGDN-EGEDE 811
T GEE E E++G E + GE ET+ Q + + ++ E + D EGE+E
Sbjct: 4898 TDNEEGEEENPLEIKEKPEEAGHEAEERGETETD-QNESQSPQEPEEGPSEDDKAEGEEE 4956
Query: 812 GEIHAEDGEMKGNEGETESQELSAENHGEAKNDEKGVEDGGGSDGGDSEEEEEEEEEQEE 871
+ A+D + G+ + + + + D++ E+GG + D + +EEEE+E+
Sbjct: 4957 MDTGADDQD--GDAAQHPEEHSEEQQQSVEEKDKEADEEGGENGPADQGFQPQEEEERED 5014
Query: 872 EEEEEEQEEEEEEEE 886
+ EE+ E E +E
Sbjct: 5015 SDTEEQVPEALERKE 5029
Score = 62.4 bits (150), Expect = 2e-09
Identities = 59/223 (26%), Positives = 94/223 (42%), Gaps = 27/223 (12%)
Query: 687 LAKEKEEESLNQGARAQPQAKAESKPEEEEPAKLPAVTVTPAPVPDIKGDQKE-NP--GG 743
+AK+ +S N Q K E K E E + + D+ E +P G
Sbjct: 4810 VAKDDNLDSGNSNKDKSQQDKKEEKEEAEADDGGQGEDKINEQIDERDYDENEVDPYHGN 4869
Query: 744 QEDVAEAESTGEMPGEEGETAGEGETEEKSGGETQPEGEGETETQGKGEECEDENEAEGK 803
QE V E E+ ++P + ++E+K+GGE EGE E + +E +E
Sbjct: 4870 QEKVPEPEAL-DLPDDLNL-----DSEDKNGGEDTDNEEGEEENPLEIKEKPEE------ 4917
Query: 804 GDNEGEDEGEIHAEDGEMKGNEGETESQELSAENHGEAKNDEKGVEDGGGSDGGDSEEEE 863
+E E+ GE + E + + E + GE + D G +D G EE
Sbjct: 4918 AGHEAEERGETETDQNESQSPQEPEEGPSEDDKAEGEEEMD-TGADDQDGDAAQHPEEHS 4976
Query: 864 EEEEEQEEEEEEEEQEE-----------EEEEEEEEEEKGNEE 895
EE+++ EE+++E EE + +EEEE E+ EE
Sbjct: 4977 EEQQQSVEEKDKEADEEGGENGPADQGFQPQEEEEREDSDTEE 5019
Score = 58.9 bits (141), Expect = 3e-08
Identities = 52/222 (23%), Positives = 95/222 (42%), Gaps = 21/222 (9%)
Query: 689 KEKEEESLNQGARAQPQAKAESKPEEEEPAKLPAVTVTPAPVPDIKGDQKENPGGQEDVA 748
+E EEE N+ P +EE ++L A K +++ +++ A
Sbjct: 4785 EEDEEEEDNKTEETGPGM-------DEEDSELVAKDDNLDSGNSNKDKSQQDKKEEKEEA 4837
Query: 749 EAESTGEMPGEEGETAGEGETEEKS------GGETQPEGEGETETQGKGEECEDENEAEG 802
EA+ G+ + E E + +E E PE E + ED+N E
Sbjct: 4838 EADDGGQGEDKINEQIDERDYDENEVDPYHGNQEKVPEPEALDLPDDLNLDSEDKNGGED 4897
Query: 803 KGDNEGEDEGEIHA-EDGEMKGNEGETESQELSAENHGEAKND-EKGVEDGGGSDG---- 856
+ EGE+E + E E G+E E + + +N ++ + E+G + ++G
Sbjct: 4898 TDNEEGEEENPLEIKEKPEEAGHEAEERGETETDQNESQSPQEPEEGPSEDDKAEGEEEM 4957
Query: 857 --GDSEEEEEEEEEQEEEEEEEEQEEEEEEEEEEEEKGNEEP 896
G +++ + + EE EE++Q EE+++E +EE G P
Sbjct: 4958 DTGADDQDGDAAQHPEEHSEEQQQSVEEKDKEADEEGGENGP 4999
Score = 56.2 bits (134), Expect = 2e-07
Identities = 44/175 (25%), Positives = 74/175 (42%), Gaps = 13/175 (7%)
Query: 742 GGQEDVAEAESTGEMPGEEGETAGEGETEEKSGGETQPEGE---------GETETQGKGE 792
G + D + G+ EE E + +TEE G + + E + K +
Sbjct: 4768 GEEADKLDERLWGDDDEEEDEEEEDNKTEETGPGMDEEDSELVAKDDNLDSGNSNKDKSQ 4827
Query: 793 ECEDENEAEGKGDNEGEDEGEIHAEDGEMKGNEGETE----SQELSAENHGEAKNDEKGV 848
+ + E + E + D+ G+ E +I+ + E +E E + +QE E D+ +
Sbjct: 4828 QDKKEEKEEAEADDGGQGEDKINEQIDERDYDENEVDPYHGNQEKVPEPEALDLPDDLNL 4887
Query: 849 EDGGGSDGGDSEEEEEEEEEQEEEEEEEEQEEEEEEEEEEEEKGNEEPLSLDWPE 903
+ + G D++ EE EEE E +E+ E+ E EE E E E S PE
Sbjct: 4888 DSEDKNGGEDTDNEEGEEENPLEIKEKPEEAGHEAEERGETETDQNESQSPQEPE 4942
Score = 52.8 bits (125), Expect = 2e-06
Identities = 57/236 (24%), Positives = 101/236 (42%), Gaps = 27/236 (11%)
Query: 687 LAKEKEEESLNQGARAQPQAKAESKPEEEEPAKLPAVTVTPAPVPDI--KGDQK--ENPG 742
L KE E+S +GA + E E + V D KG +K E+P
Sbjct: 4656 LPKEFMEDSAGEGATEFHDYEGGGIGEGEGMKDVSDQIGNEEQVEDTFQKGQEKDKEDPD 4715
Query: 743 GQEDVAEAESTGEMPGEEGETAGEGETEEKSGGETQPEGEGETETQG----KGEECEDEN 798
+ D+ ++ EM + +GE EE+ + + + EG + GEE + +
Sbjct: 4716 SKSDIKGEDNAIEMSEDFDGKMHDGELEEQEEDDEKSDSEGGDLDKHMGDLNGEEADKLD 4775
Query: 799 EAEGKGDNEGEDEGEIHAEDGEMKGNEGETESQELSAENHGEAKNDEKGVEDGGGSDGGD 858
E D+E EDE E + E E +S+ ++ +++ ++ N K D
Sbjct: 4776 ERLWGDDDEEEDEEEEDNKTEETGPGMDEEDSELVAKDDNLDSGNSNK--------DKSQ 4827
Query: 859 SEEEEEEEEEQ-------EEEEEEEEQEEEEEEEEEEEEKGNE----EPLSLDWPE 903
+++EE+EE + E++ E+ E + +E E + GN+ EP +LD P+
Sbjct: 4828 QDKKEEKEEAEADDGGQGEDKINEQIDERDYDENEVDPYHGNQEKVPEPEALDLPD 4883
Score = 47.8 bits (112), Expect = 6e-05
Identities = 45/200 (22%), Positives = 81/200 (40%), Gaps = 27/200 (13%)
Query: 735 GDQKENPGGQEDVAEAESTGEMPGEEG-----------------ETAGEGETEEKSGGET 777
GD E +E+ + E TG EE + + + + EEK E
Sbjct: 4780 GDDDEEEDEEEEDNKTEETGPGMDEEDSELVAKDDNLDSGNSNKDKSQQDKKEEKEEAEA 4839
Query: 778 QPEGEGETETQGKGEECE-DENEAE---GKGDNEGEDEG-----EIHAEDGEMKGNEGET 828
G+GE + + +E + DENE + G + E E +++ + + G E +T
Sbjct: 4840 DDGGQGEDKINEQIDERDYDENEVDPYHGNQEKVPEPEALDLPDDLNLDSEDKNGGE-DT 4898
Query: 829 ESQELSAENHGEAKNDEKGVEDGGGSDGGDSEEEEEEEEEQEEEEEEEEQEEEEEEEEEE 888
+++E EN E K + G ++ E + QE EE E ++ E EEE +
Sbjct: 4899 DNEEGEEENPLEIKEKPEEAGHEAEERGETETDQNESQSPQEPEEGPSEDDKAEGEEEMD 4958
Query: 889 EEKGNEEPLSLDWPETRQKQ 908
+++ + PE ++
Sbjct: 4959 TGADDQDGDAAQHPEEHSEE 4978
Score = 46.6 bits (109), Expect = 1e-04
Identities = 51/213 (23%), Positives = 80/213 (37%), Gaps = 30/213 (14%)
Query: 709 ESKPEEEEPAKLPAVTVTPAPVPD-------IKGDQKENPGGQEDVAEAESTGEMPGEEG 761
E + EEEE K T P D K D ++ +D ++ + E E
Sbjct: 4784 EEEDEEEEDNK----TEETGPGMDEEDSELVAKDDNLDSGNSNKDKSQQDKKEEKEEAEA 4839
Query: 762 ETAGEGETEEKSGGETQPEGEGETETQGKGEECEDENEAEGKGDN---EGEDEGEIHAED 818
+ G+GE + + + E E + +E E EA D+ + ED+ D
Sbjct: 4840 DDGGQGEDKINEQIDERDYDENEVDPYHGNQEKVPEPEALDLPDDLNLDSEDKNGGEDTD 4899
Query: 819 GEMKGNEGETESQELSAENHGEAKNDEKGVEDGGGSDGGDSEEEEEEEEEQEEEEEE--- 875
E E E +E E EA+ + D S EE E+++ E EEE
Sbjct: 4900 NEEGEEENPLEIKEKPEEAGHEAEERGETETDQNESQSPQEPEEGPSEDDKAEGEEEMDT 4959
Query: 876 -------------EEQEEEEEEEEEEEEKGNEE 895
EE EE+++ EE++K +E
Sbjct: 4960 GADDQDGDAAQHPEEHSEEQQQSVEEKDKEADE 4992
Score = 44.7 bits (104), Expect = 5e-04
Identities = 54/245 (22%), Positives = 93/245 (37%), Gaps = 38/245 (15%)
Query: 689 KEKEEESLNQGARAQPQAKAESKPEEEEPAKLPAVTVTPAPVPDIKGDQKENPGGQEDVA 748
+EK++E+ +G P + EEEE + T VP+ ++ GQ V
Sbjct: 4984 EEKDKEADEEGGENGPADQGFQPQEEEERED----SDTEEQVPEALERKEHASCGQTGVE 5039
Query: 749 EAESTG--EMPGEEGETAGEGETEEKSGGETQPEGEGETET--------QGKGEECEDEN 798
++T E+ G E +G+ E SG + EG + + +
Sbjct: 5040 NMQNTQAMELAGAAPEKE-QGKEEHGSGAADANQAEGHESNFIAQLASQKHTRKNTQSFK 5098
Query: 799 EAEGKGDNE---GEDEGEIHAE----DGEMKGNEGETESQELSAENHGEAKNDEKGVE-- 849
G+ DNE G+ +H D + +G + + E+ ++ ++G +
Sbjct: 5099 RKPGQADNERSMGDHNERVHKRLRTVDTDSHAEQGPAQQPQAQVEDADAFEHIKQGSDAY 5158
Query: 850 -------------DGGGSDGGDSEEEEEEEEEQEEEEEEEEQEEEEEEEEEEEEK-GNEE 895
G D EEEE E+ + EE+EE + + E+ + EE K G
Sbjct: 5159 DAQTYDVASKEQQQSAKDSGKDQEEEEIEDTLMDTEEQEEFKAADVEQLKPEEIKSGTTA 5218
Query: 896 PLSLD 900
PL D
Sbjct: 5219 PLGFD 5223
Score = 43.1 bits (100), Expect = 0.001
Identities = 62/252 (24%), Positives = 99/252 (39%), Gaps = 53/252 (21%)
Query: 689 KEKEEESLNQGARAQPQAKAESKPEEEEPAKLPAVTVTPAPVPDIKG-----DQKENPGG 743
K + EE ++ GA Q A PEE + +V + G DQ P
Sbjct: 4950 KAEGEEEMDTGADDQ-DGDAAQHPEEHSEEQQQSVEEKDKEADEEGGENGPADQGFQPQE 5008
Query: 744 QEDVAEAESTGEMPG--EEGETAGEGETEEKSGGETQ--------PEGEGETETQGKGEE 793
+E+ ++++ ++P E E A G+T ++ TQ PE E E G G
Sbjct: 5009 EEEREDSDTEEQVPEALERKEHASCGQTGVENMQNTQAMELAGAAPEKEQGKEEHGSG-- 5066
Query: 794 CEDENEAEGKGDN---------------EGEDEGEIHAEDGEMKGNEGETESQEL----- 833
D N+AEG N + A++ G+ E + L
Sbjct: 5067 AADANQAEGHESNFIAQLASQKHTRKNTQSFKRKPGQADNERSMGDHNERVHKRLRTVDT 5126
Query: 834 -SAENHGEAKNDEKGVEDGG-------GSDGGDSEEEE--EEEEEQEEEEEEEEQEEEEE 883
S G A+ + VED GSD D++ + +E++Q ++ ++QEEEE
Sbjct: 5127 DSHAEQGPAQQPQAQVEDADAFEHIKQGSDAYDAQTYDVASKEQQQSAKDSGKDQEEEEI 5186
Query: 884 EE-----EEEEE 890
E+ EE+EE
Sbjct: 5187 EDTLMDTEEQEE 5198
>gi|22749303 hypothetical protein LOC196477 [Homo sapiens]
Length = 406
Score = 67.0 bits (162), Expect = 9e-11
Identities = 67/223 (30%), Positives = 93/223 (41%), Gaps = 24/223 (10%)
Query: 698 QGARAQPQAKAESKPEEE-----EPAKL-----PAVTVTPAPVPDIKGDQKENPGGQEDV 747
+G R P+ P + P KL P + P I E+ QE V
Sbjct: 148 RGLRHHPRHSYPRSPPADVSTLPRPVKLYEWREPGMRAPPNTTQFIMNQIYEDMRQQEKV 207
Query: 748 AEAESTGEMPGEEGETAGEGETEEKSGGETQPEGEGETETQGKGEEC----EDENEAEGK 803
+ + ++ +GE SG + P G ET G E ++ + A
Sbjct: 208 ERQQEA--LRAQKATVSGEASPARSSGNDAPPGGS--KETWGLQETLYGFVQNPSLAFSP 263
Query: 804 GDNEGEDEGEIHAEDGEMKGNEGETESQELSAENHGEAKNDEKGVEDGGGSDGGDSEEEE 863
E + + E+ E K N+ E E + + EA +E+ VED + D EEEE
Sbjct: 264 NPEENQSLAPLLVEEEEEKKNDDEEEYDQEVCDAK-EASEEEEEVEDEE-EEVEDEEEEE 321
Query: 864 EEE----EEQEEEEEEEEQEEEEEEEEEEEEKGNEEPLSLDWP 902
EE EE EEE EEEE EEEEE EE E++G E L L+ P
Sbjct: 322 VEEAEYVEEGEEELEEEELEEEEEVLEENEQRGEEFHLPLEMP 364
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.130 0.378
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 46,796,854
Number of Sequences: 37866
Number of extensions: 2703236
Number of successful extensions: 109207
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 1295
Number of HSP's successfully gapped in prelim test: 872
Number of HSP's that attempted gapping in prelim test: 29777
Number of HSP's gapped (non-prelim): 26233
length of query: 1099
length of database: 18,247,518
effective HSP length: 113
effective length of query: 986
effective length of database: 13,968,660
effective search space: 13773098760
effective search space used: 13773098760
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.