Guide to the Human Genome
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Search of human proteins with 4759066

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4759066 sodium channel, voltage-gated, type II, beta [Homo
sapiens]
         (215 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4759066 sodium channel, voltage-gated, type II, beta [Homo sa...   444   e-125
gi|21536337 myelin protein zero-like 2 precursor [Homo sapiens]        92   3e-19
gi|5032247 myelin protein zero-like 2 precursor [Homo sapiens]         92   3e-19
gi|28372555 sodium channel, voltage-gated, type IV, beta isoform...    82   3e-16
gi|4506357 myelin protein zero-like 1 isoform a [Homo sapiens]         69   4e-12
gi|46358426 myelin protein zero-like 1 isoform b [Homo sapiens]        67   9e-12
gi|4505243 myelin protein zero [Homo sapiens]                          66   3e-11
gi|38093645 myelin protein zero-like 3 [Homo sapiens]                  65   6e-11
gi|215272334 sodium channel, voltage-gated, type IV, beta isofor...    56   3e-08
gi|148664224 adhesion molecule, interacts with CXADR antigen 1 i...    53   2e-07
gi|148664207 adhesion molecule, interacts with CXADR antigen 1 i...    53   2e-07
gi|32699028 V-set and immunoglobulin domain containing 1 [Homo s...    53   2e-07
gi|62865876 immunoglobulin superfamily, member 11 isoform b [Hom...    52   5e-07
gi|62865874 immunoglobulin superfamily, member 11 isoform a [Hom...    51   6e-07
gi|21361429 V-set and immunoglobulin domain containing 2 [Homo s...    46   3e-05
gi|13489095 sialoadhesin precursor [Homo sapiens]                      45   6e-05
gi|42560233 poliovirus receptor-related 1 isoform 3 [Homo sapiens]     43   2e-04
gi|42560231 poliovirus receptor-related 1 isoform 2 [Homo sapiens]     43   2e-04
gi|42560237 poliovirus receptor-related 1 isoform 1 [Homo sapiens]     43   2e-04
gi|4503173 coxsackie virus and adenovirus receptor precursor [Ho...    42   5e-04
gi|9055238 voltage-gated sodium channel beta-3 subunit precursor...    40   0.001
gi|93587332 voltage-gated sodium channel beta-3 subunit precurso...    40   0.001
gi|61966777 V-set and immunoglobulin domain containing 8 [Homo s...    40   0.002
gi|226529863 T-cell immunoglobulin and mucin domain containing 4...    39   0.003
gi|226498466 T-cell immunoglobulin and mucin domain containing 4...    39   0.003
gi|239753613 PREDICTED: similar to hCG1657343 [Homo sapiens]           38   0.006
gi|239748209 PREDICTED: similar to hCG1657343 [Homo sapiens]           38   0.006
gi|239742107 PREDICTED: similar to hCG1657343 [Homo sapiens]           38   0.006
gi|222136611 poliovirus receptor-related 4 [Homo sapiens]              38   0.006
gi|5031561 transmembrane glycoprotein A33 precursor [Homo sapiens]     38   0.006

>gi|4759066 sodium channel, voltage-gated, type II, beta [Homo
           sapiens]
          Length = 215

 Score =  444 bits (1142), Expect = e-125
 Identities = 215/215 (100%), Positives = 215/215 (100%)

Query: 1   MHRDAWLPRPAFSLTGLSLFFSLVPPGRSMEVTVPATLNVLNGSDARLPCTFNSCYTVNH 60
           MHRDAWLPRPAFSLTGLSLFFSLVPPGRSMEVTVPATLNVLNGSDARLPCTFNSCYTVNH
Sbjct: 1   MHRDAWLPRPAFSLTGLSLFFSLVPPGRSMEVTVPATLNVLNGSDARLPCTFNSCYTVNH 60

Query: 61  KQFSLNWTYQECNNCSEEMFLQFRMKIINLKLERFQDRVEFSGNPSKYDVSVMLRNVQPE 120
           KQFSLNWTYQECNNCSEEMFLQFRMKIINLKLERFQDRVEFSGNPSKYDVSVMLRNVQPE
Sbjct: 61  KQFSLNWTYQECNNCSEEMFLQFRMKIINLKLERFQDRVEFSGNPSKYDVSVMLRNVQPE 120

Query: 121 DEGIYNCYIMNPPDRHRGHGKIHLQVLMEEPPERDSTVAVIVGASVGGFLAVVILVLMVV 180
           DEGIYNCYIMNPPDRHRGHGKIHLQVLMEEPPERDSTVAVIVGASVGGFLAVVILVLMVV
Sbjct: 121 DEGIYNCYIMNPPDRHRGHGKIHLQVLMEEPPERDSTVAVIVGASVGGFLAVVILVLMVV 180

Query: 181 KCVRRKKEQKLSTDDLKTEEEGKTDGEGNPDDGAK 215
           KCVRRKKEQKLSTDDLKTEEEGKTDGEGNPDDGAK
Sbjct: 181 KCVRRKKEQKLSTDDLKTEEEGKTDGEGNPDDGAK 215


>gi|21536337 myelin protein zero-like 2 precursor [Homo sapiens]
          Length = 215

 Score = 92.0 bits (227), Expect = 3e-19
 Identities = 56/201 (27%), Positives = 104/201 (51%), Gaps = 6/201 (2%)

Query: 9   RPAFSLTGLSLFFSLVPPGRSMEVTVPATLNVLNGSDARLPCTFNSCYTVNHKQFSLNWT 68
           R    L G+ L  + + P  ++E+     L  +NG+DARL CTF+S   V     ++ W 
Sbjct: 8   RAVLLLLGIQL--TALWPIAAVEIYTSRVLEAVNGTDARLKCTFSSFAPVGDA-LTVTWN 64

Query: 69  YQECNNCSEEMFLQFRMKIINLKLERFQDRVEFSGNPSKYDVSVMLRNVQPEDEGIYNCY 128
           ++  +   E+    + +        RF+DRV + GNP +YD S++L  +Q +D G Y C 
Sbjct: 65  FRPLDGGPEQFVFYYHIDPFQPMSGRFKDRVSWDGNPERYDASILLWKLQFDDNGTYTCQ 124

Query: 129 IMNPPDRHRGHGKIHLQVLMEEPPERDSTVAVIVGASVGGFLAVVILVLMVVKCVRRKK- 187
           + NPPD     G+I L V+          +A+ +G S    + ++++V+++ +  R+K+ 
Sbjct: 125 VKNPPDVDGVIGEIRLSVVHTVRFSEIHFLALAIG-SACALMIIIVIVVVLFQHYRKKRW 183

Query: 188 -EQKLSTDDLKTEEEGKTDGE 207
            E+     ++K++EE + + E
Sbjct: 184 AERAHKVVEIKSKEEERLNQE 204


>gi|5032247 myelin protein zero-like 2 precursor [Homo sapiens]
          Length = 215

 Score = 92.0 bits (227), Expect = 3e-19
 Identities = 56/201 (27%), Positives = 104/201 (51%), Gaps = 6/201 (2%)

Query: 9   RPAFSLTGLSLFFSLVPPGRSMEVTVPATLNVLNGSDARLPCTFNSCYTVNHKQFSLNWT 68
           R    L G+ L  + + P  ++E+     L  +NG+DARL CTF+S   V     ++ W 
Sbjct: 8   RAVLLLLGIQL--TALWPIAAVEIYTSRVLEAVNGTDARLKCTFSSFAPVGDA-LTVTWN 64

Query: 69  YQECNNCSEEMFLQFRMKIINLKLERFQDRVEFSGNPSKYDVSVMLRNVQPEDEGIYNCY 128
           ++  +   E+    + +        RF+DRV + GNP +YD S++L  +Q +D G Y C 
Sbjct: 65  FRPLDGGPEQFVFYYHIDPFQPMSGRFKDRVSWDGNPERYDASILLWKLQFDDNGTYTCQ 124

Query: 129 IMNPPDRHRGHGKIHLQVLMEEPPERDSTVAVIVGASVGGFLAVVILVLMVVKCVRRKK- 187
           + NPPD     G+I L V+          +A+ +G S    + ++++V+++ +  R+K+ 
Sbjct: 125 VKNPPDVDGVIGEIRLSVVHTVRFSEIHFLALAIG-SACALMIIIVIVVVLFQHYRKKRW 183

Query: 188 -EQKLSTDDLKTEEEGKTDGE 207
            E+     ++K++EE + + E
Sbjct: 184 AERAHKVVEIKSKEEERLNQE 204


>gi|28372555 sodium channel, voltage-gated, type IV, beta isoform 1
           precursor [Homo sapiens]
          Length = 228

 Score = 82.4 bits (202), Expect = 3e-16
 Identities = 63/206 (30%), Positives = 108/206 (52%), Gaps = 26/206 (12%)

Query: 15  TGLSLFFSLVPPGRSMEVTVPATLNV--LNGSDARLPCTFNSCYTVNHKQFSLNWTYQEC 72
           TGL   F L+P   S+EV+V    ++  +NG++  LPCTF+SC+      F   WTY   
Sbjct: 17  TGLLGLF-LLPVTLSLEVSVGKATDIYAVNGTEILLPCTFSSCFGFEDLHF--RWTY--- 70

Query: 73  NNCSEEMFLQFRMKIINLKLE-----RFQDRVEFSGNPSKY--DVSVMLRNVQPEDEGIY 125
            N S+   +     + N K +     +  DR+   G+  +   ++S++LR+++  D G Y
Sbjct: 71  -NSSDAFKILIEGTVKNEKSDPKVTLKDDDRITLVGSTKEKMNNISIVLRDLEFSDTGKY 129

Query: 126 NCYIMNPPDRH-RGHGKIHLQVLMEEPPERDSTVAVIVGASVGGFLAVVILVLMVVKCV- 183
            C++ NP + + + H  I LQV ++   E D+TV +I+ A VGG + ++IL+L++ K + 
Sbjct: 130 TCHVKNPKENNLQHHATIFLQV-VDRLEEVDNTVTLIILAVVGGVIGLLILILLIKKLII 188

Query: 184 -------RRKKEQKLSTDDLKTEEEG 202
                   +KKE  +S+      E G
Sbjct: 189 FILKKTREKKKECLVSSSGNDNTENG 214


>gi|4506357 myelin protein zero-like 1 isoform a [Homo sapiens]
          Length = 269

 Score = 68.6 bits (166), Expect = 4e-12
 Identities = 49/173 (28%), Positives = 80/173 (46%), Gaps = 3/173 (1%)

Query: 29  SMEVTVPATLNVLNGSDARLPCTFNSCYTVNHKQFSLNWTYQECNNCSEEMFLQFRMKII 88
           ++EV  P  + V NG+  +L C F S  T      S++W++Q     +   F  +    +
Sbjct: 37  ALEVYTPKEIFVANGTQGKLTCKFKSTSTTGGLT-SVSWSFQPEGADTTVSFFHYSQGQV 95

Query: 89  NL-KLERFQDRVEFSGNPSKYDVSVMLRNVQPEDEGIYNCYIMNPPDRHRGHGKIHLQVL 147
            L     F+DR+ ++G+  K D S+ + N+Q    G Y C + NPPD     G I L V 
Sbjct: 96  YLGNYPPFKDRISWAGDLDKKDASINIENMQFIHNGTYICDVKNPPDIVVQPGHIRLYV- 154

Query: 148 MEEPPERDSTVAVIVGASVGGFLAVVILVLMVVKCVRRKKEQKLSTDDLKTEE 200
           +E+       V V+VG      L + +L+ M++  + R+K  K       T E
Sbjct: 155 VEKENLPVFPVWVVVGIVTAVVLGLTLLISMILAVLYRRKNSKRDYTGCSTSE 207


>gi|46358426 myelin protein zero-like 1 isoform b [Homo sapiens]
          Length = 209

 Score = 67.4 bits (163), Expect = 9e-12
 Identities = 47/163 (28%), Positives = 78/163 (47%), Gaps = 3/163 (1%)

Query: 29  SMEVTVPATLNVLNGSDARLPCTFNSCYTVNHKQFSLNWTYQECNNCSEEMFLQFRMKII 88
           ++EV  P  + V NG+  +L C F S  T      S++W++Q     +   F  +    +
Sbjct: 37  ALEVYTPKEIFVANGTQGKLTCKFKSTSTTGGLT-SVSWSFQPEGADTTVSFFHYSQGQV 95

Query: 89  NL-KLERFQDRVEFSGNPSKYDVSVMLRNVQPEDEGIYNCYIMNPPDRHRGHGKIHLQVL 147
            L     F+DR+ ++G+  K D S+ + N+Q    G Y C + NPPD     G I L V 
Sbjct: 96  YLGNYPPFKDRISWAGDLDKKDASINIENMQFIHNGTYICDVKNPPDIVVQPGHIRLYV- 154

Query: 148 MEEPPERDSTVAVIVGASVGGFLAVVILVLMVVKCVRRKKEQK 190
           +E+       V V+VG      L + +L+ M++  + R+K  K
Sbjct: 155 VEKENLPVFPVWVVVGIVTAVVLGLTLLISMILAVLYRRKNSK 197


>gi|4505243 myelin protein zero [Homo sapiens]
          Length = 258

 Score = 65.9 bits (159), Expect = 3e-11
 Identities = 55/194 (28%), Positives = 93/194 (47%), Gaps = 9/194 (4%)

Query: 19  LFFSLV-PPGRSMEVTVPATLNVLNGSDARLPCTFNSCYTVNHKQFSLNWTYQ-ECNNCS 76
           LF SLV  P +++ V     ++   GS   L C+F S   V+    S  W YQ E    +
Sbjct: 28  LFSSLVLSPAQAIVVYTDREVHGAVGSRVTLHCSFWSSEWVSD-DISFTWRYQPEGGRDA 86

Query: 77  EEMFLQFRMKIINLKLERFQDRVEFSGNPSKYDVSVMLRNVQPEDEGIYNCYIMNPPDRH 136
             +F   + +    ++  F++R+++ G+P   D S+++ N+   D G + C + NPPD  
Sbjct: 87  ISIFHYAKGQPYIDEVGTFKERIQWVGDPRWKDGSIVIHNLDYSDNGTFTCDVKNPPDIV 146

Query: 137 RGHGKIHLQVLMEEPPERDSTVAVIVGASVGGFLAVVILVLMVVKCVRR--KKEQKLSTD 194
               ++ L V  + P    +   V++GA +GG L VV+L+L++   VR    + Q     
Sbjct: 147 GKTSQVTLYVFEKVP----TRYGVVLGAVIGGVLGVVLLLLLLFYVVRYCWLRRQAALQR 202

Query: 195 DLKTEEEGKTDGEG 208
            L   E+GK    G
Sbjct: 203 RLSAMEKGKLHKPG 216


>gi|38093645 myelin protein zero-like 3 [Homo sapiens]
          Length = 235

 Score = 64.7 bits (156), Expect = 6e-11
 Identities = 56/203 (27%), Positives = 91/203 (44%), Gaps = 18/203 (8%)

Query: 12  FSLTGLSLFFSLVPPGRSMEVTVPATLNVLNGSDARLPCTFNSCYTVNHKQFSLNWTYQE 71
           F L G+ LFF  V    S+E+   A +    G   +L CTF S   V  K  +++WTY+ 
Sbjct: 15  FPLLGV-LFFQGVYIVFSLEIRADAHVRGYVGEKIKLKCTFKSTSDVTDK-LTIDWTYRP 72

Query: 72  CNNCSEEMFLQFRMKIINLKLERFQDRVEFSGNPSKYDVSVMLRNVQPEDEGIYNCYIMN 131
            ++        ++          F+DR+ + GN  K D S+ + N   +D G ++C + N
Sbjct: 73  PSSSHTVSIFHYQSFQYPTTAGTFRDRISWVGNVYKGDASISISNPTIKDNGTFSCAVKN 132

Query: 132 PPDRHRGHGKIHLQVLMEEPPERDSTVAVIVGASVGGFL-AVVILVLMVVKCVRR----- 185
           PPD H       L V         S+VA++   S+  F+ + V++ L++V+  R+     
Sbjct: 133 PPDVHHNIPMTELTVTERGFGTMLSSVALL---SILVFVPSAVVVALLLVRMGRKAAGLK 189

Query: 186 -------KKEQKLSTDDLKTEEE 201
                  KK     +DD   EEE
Sbjct: 190 KRSRSGYKKSSIEVSDDTDQEEE 212


>gi|215272334 sodium channel, voltage-gated, type IV, beta isoform 3
           [Homo sapiens]
          Length = 118

 Score = 55.8 bits (133), Expect = 3e-08
 Identities = 33/103 (32%), Positives = 60/103 (58%), Gaps = 10/103 (9%)

Query: 109 DVSVMLRNVQPEDEGIYNCYIMNPPDRH-RGHGKIHLQVLMEEPPERDSTVAVIVGASVG 167
           ++S++LR+++  D G Y C++ NP + + + H  I LQV ++   E D+TV +I+ A VG
Sbjct: 3   NISIVLRDLEFSDTGKYTCHVKNPKENNLQHHATIFLQV-VDRLEEVDNTVTLIILAVVG 61

Query: 168 GFLAVVILVLMVVKCV--------RRKKEQKLSTDDLKTEEEG 202
           G + ++IL+L++ K +         +KKE  +S+      E G
Sbjct: 62  GVIGLLILILLIKKLIIFILKKTREKKKECLVSSSGNDNTENG 104


>gi|148664224 adhesion molecule, interacts with CXADR antigen 1
           isoform 2 [Homo sapiens]
          Length = 384

 Score = 53.1 bits (126), Expect = 2e-07
 Identities = 37/119 (31%), Positives = 57/119 (47%), Gaps = 3/119 (2%)

Query: 35  PATLNVLNGSDARLPCTFNSCYTVNHKQFSLNWTYQECNNCSEEMFLQFRMKIINLKLER 94
           P  L V  G  A + C F S  T +   F ++WT     +  +E  L +   + ++ + R
Sbjct: 17  PPELTVHVGDSALMGCVFQS--TEDKCIFKIDWTLSPGEHAKDEYVLYYYSNL-SVPIGR 73

Query: 95  FQDRVEFSGNPSKYDVSVMLRNVQPEDEGIYNCYIMNPPDRHRGHGKIHLQVLMEEPPE 153
           FQ+RV   G+    D S++L++VQ  D+G Y C I    +       + L VL EEP E
Sbjct: 74  FQNRVHLMGDILCNDGSLLLQDVQEADQGTYICEIRLKGESQVFKKAVVLHVLPEEPKE 132



 Score = 38.9 bits (89), Expect = 0.003
 Identities = 41/172 (23%), Positives = 68/172 (39%), Gaps = 28/172 (16%)

Query: 35  PATLNVLNGSDARLPCTFNSCYTVNHKQFSLNWTYQECNNCSEEMFLQFRMKIINLKLER 94
           P  L V  G   ++ C F S   V H    + W +       E +F  +    ++++  +
Sbjct: 130 PKELMVHVGGLIQMGCVFQST-EVKHVT-KVEWIFSGRRAKEEIVFRYYHKLRMSVEYSQ 187

Query: 95  ----FQDRVEFSGNPSKYDVSVMLRNVQPEDEGIYNCYIMNPPDRHRGHGKIHLQVLMEE 150
               FQ+RV   G+  + D S+ML+ V+  D G Y C I      H G+      +++  
Sbjct: 188 SWGHFQNRVNLVGDIFRNDGSIMLQGVRESDGGNYTCSI------HLGNLVFKKTIVLHV 241

Query: 151 PPERDST----------------VAVIVGASVGGFLAVVILVLMVVKCVRRK 186
            PE   T                + +IVG      L + +L+L+V K    K
Sbjct: 242 SPEEPRTLVTPAALRPLVLGGNQLVIIVGIVCATILLLPVLILIVKKTCGNK 293


>gi|148664207 adhesion molecule, interacts with CXADR antigen 1
           isoform 1 [Homo sapiens]
          Length = 394

 Score = 53.1 bits (126), Expect = 2e-07
 Identities = 37/119 (31%), Positives = 57/119 (47%), Gaps = 3/119 (2%)

Query: 35  PATLNVLNGSDARLPCTFNSCYTVNHKQFSLNWTYQECNNCSEEMFLQFRMKIINLKLER 94
           P  L V  G  A + C F S  T +   F ++WT     +  +E  L +   + ++ + R
Sbjct: 27  PPELTVHVGDSALMGCVFQS--TEDKCIFKIDWTLSPGEHAKDEYVLYYYSNL-SVPIGR 83

Query: 95  FQDRVEFSGNPSKYDVSVMLRNVQPEDEGIYNCYIMNPPDRHRGHGKIHLQVLMEEPPE 153
           FQ+RV   G+    D S++L++VQ  D+G Y C I    +       + L VL EEP E
Sbjct: 84  FQNRVHLMGDILCNDGSLLLQDVQEADQGTYICEIRLKGESQVFKKAVVLHVLPEEPKE 142



 Score = 38.9 bits (89), Expect = 0.003
 Identities = 41/172 (23%), Positives = 68/172 (39%), Gaps = 28/172 (16%)

Query: 35  PATLNVLNGSDARLPCTFNSCYTVNHKQFSLNWTYQECNNCSEEMFLQFRMKIINLKLER 94
           P  L V  G   ++ C F S   V H    + W +       E +F  +    ++++  +
Sbjct: 140 PKELMVHVGGLIQMGCVFQST-EVKHVT-KVEWIFSGRRAKEEIVFRYYHKLRMSVEYSQ 197

Query: 95  ----FQDRVEFSGNPSKYDVSVMLRNVQPEDEGIYNCYIMNPPDRHRGHGKIHLQVLMEE 150
               FQ+RV   G+  + D S+ML+ V+  D G Y C I      H G+      +++  
Sbjct: 198 SWGHFQNRVNLVGDIFRNDGSIMLQGVRESDGGNYTCSI------HLGNLVFKKTIVLHV 251

Query: 151 PPERDST----------------VAVIVGASVGGFLAVVILVLMVVKCVRRK 186
            PE   T                + +IVG      L + +L+L+V K    K
Sbjct: 252 SPEEPRTLVTPAALRPLVLGGNQLVIIVGIVCATILLLPVLILIVKKTCGNK 303


>gi|32699028 V-set and immunoglobulin domain containing 1 [Homo
           sapiens]
          Length = 387

 Score = 52.8 bits (125), Expect = 2e-07
 Identities = 34/122 (27%), Positives = 66/122 (54%), Gaps = 6/122 (4%)

Query: 30  MEVTVP-ATLNVLNGSDARLPCTFNSCYTVNHKQFSLNWTYQECNNCSEEMFLQFRMKII 88
           ++VT+P   +NV  GS+  L C + +    + +Q S+ W++       E + + F     
Sbjct: 22  VQVTIPDGFVNVTVGSNVTLICIYTTT-VASREQLSIQWSFFHKKEM-EPISIYFSQGGQ 79

Query: 89  NLKLERFQDRVEFSGNPSKYDVSVMLRNVQPEDEGIYNCYIMNPPD-RHRGHGKIHLQVL 147
            + + +F+DR+  S +P   + S+ + ++QP D GIY C + NPPD   +  G +++ VL
Sbjct: 80  AVAIGQFKDRITGSNDPG--NASITISHMQPADSGIYICDVNNPPDFLGQNQGILNVSVL 137

Query: 148 ME 149
           ++
Sbjct: 138 VK 139


>gi|62865876 immunoglobulin superfamily, member 11 isoform b [Homo
           sapiens]
          Length = 431

 Score = 51.6 bits (122), Expect = 5e-07
 Identities = 38/120 (31%), Positives = 56/120 (46%), Gaps = 8/120 (6%)

Query: 19  LFFSLVPPGRSMEVTV-PATLNVLNGSDARLPCTFNSCYTVNHKQFSLN--WTYQECNNC 75
           L  SL     S+EV+  P ++ V  G  A LPCTF    T +    +LN  W     +N 
Sbjct: 12  LLLSLHGVAASLEVSESPGSIQVARGQPAVLPCTF----TTSAALINLNVIWMVTPLSNA 67

Query: 76  SE-EMFLQFRMKIINLKLERFQDRVEFSGNPSKYDVSVMLRNVQPEDEGIYNCYIMNPPD 134
           ++ E  + ++   +     RF  RV F+G     +VS+ + N Q  D G Y C + N PD
Sbjct: 68  NQPEQVILYQGGQMFDGAPRFHGRVGFTGTMPATNVSIFINNTQLSDTGTYQCLVNNLPD 127


>gi|62865874 immunoglobulin superfamily, member 11 isoform a [Homo
           sapiens]
          Length = 430

 Score = 51.2 bits (121), Expect = 6e-07
 Identities = 37/118 (31%), Positives = 55/118 (46%), Gaps = 8/118 (6%)

Query: 21  FSLVPPGRSMEVTV-PATLNVLNGSDARLPCTFNSCYTVNHKQFSLN--WTYQECNNCSE 77
           FS      S+EV+  P ++ V  G  A LPCTF    T +    +LN  W     +N ++
Sbjct: 13  FSRTGVAASLEVSESPGSIQVARGQPAVLPCTF----TTSAALINLNVIWMVTPLSNANQ 68

Query: 78  -EMFLQFRMKIINLKLERFQDRVEFSGNPSKYDVSVMLRNVQPEDEGIYNCYIMNPPD 134
            E  + ++   +     RF  RV F+G     +VS+ + N Q  D G Y C + N PD
Sbjct: 69  PEQVILYQGGQMFDGAPRFHGRVGFTGTMPATNVSIFINNTQLSDTGTYQCLVNNLPD 126


>gi|21361429 V-set and immunoglobulin domain containing 2 [Homo
           sapiens]
          Length = 327

 Score = 45.8 bits (107), Expect = 3e-05
 Identities = 55/172 (31%), Positives = 75/172 (43%), Gaps = 13/172 (7%)

Query: 5   AWLPRPAFSLTGLSLFFSLVPPGRSMEVTVPAT-LNVLNGSDARLPCTFNSCYTVNHKQF 63
           A LP P   L G  L F L   G ++EV VP   L+   G  A L CT++   T     F
Sbjct: 2   AELPGPF--LCGALLGF-LCLSGLAVEVKVPTEPLSTPLGKTAELTCTYS---TSVGDSF 55

Query: 64  SLNWTY-QECNNCSEEMFLQFRMKIINLKLERFQDRVEFSGNPSKYDVSVM-LRNVQPED 121
           +L W++ Q     SE   + +              RV    NP    V+ + L +V P D
Sbjct: 56  ALEWSFVQPGKPISESHPILYFTNGHLYPTGSKSKRVSLLQNPPTVGVATLKLTDVHPSD 115

Query: 122 EGIYNCYIMNPPDRH-RGHGKIHLQVLMEEPPERDSTVAVIVGASVGGFLAV 172
            G Y C + NPPD +  G G I+L VL+   P  +   +     SVGG  A+
Sbjct: 116 TGTYLCQVNNPPDFYTNGLGLINLTVLV---PPSNPLCSQSGQTSVGGSTAL 164


>gi|13489095 sialoadhesin precursor [Homo sapiens]
          Length = 1709

 Score = 44.7 bits (104), Expect = 6e-05
 Identities = 43/156 (27%), Positives = 65/156 (41%), Gaps = 6/156 (3%)

Query: 14  LTGLSLFFSLVPPGR-SMEVTVPATLNVLNGSDARLPCTFNSCYTVNHKQFSLNWTYQEC 72
           L  L L  S  P G+ S  V+ P  +  + GS   +PC F+    V          Y + 
Sbjct: 4   LPKLLLLASFFPAGQASWGVSSPQDVQGVKGSCLLIPCIFSFPADVEVPDGITAIWYYDY 63

Query: 73  NNCSEEMFLQFRMKIINLKLERFQDRVEFSGNPSKYDVSVMLRNVQPEDEGIYNCYIMNP 132
           +   + +      K++     RF+ R EF GNP     +++L+++QPED G YN      
Sbjct: 64  SGQRQVVSHSADPKLVEA---RFRGRTEFMGNPEHRVCNLLLKDLQPEDSGSYNFRFEIS 120

Query: 133 PDRHRGHGKIHLQVLMEEP--PERDSTVAVIVGASV 166
                   K  L  + EEP  P   S V ++ G  V
Sbjct: 121 EVNRWSDVKGTLVTVTEEPRVPTIASPVELLEGTEV 156


>gi|42560233 poliovirus receptor-related 1 isoform 3 [Homo sapiens]
          Length = 352

 Score = 43.1 bits (100), Expect = 2e-04
 Identities = 42/147 (28%), Positives = 71/147 (48%), Gaps = 9/147 (6%)

Query: 16  GLSLFFSLVPPGRSMEVTVPATLNVLNGSDARLPCTF-NSCYTVNHKQFSLNWTYQECNN 74
           GL+ FF  +P   S  V V  ++    G+D  L C+F N   +V   Q     T+Q+  N
Sbjct: 19  GLTAFF--LPGVHSQVVQVNDSMYGFIGTDVVLHCSFANPLPSVKITQV----TWQKSTN 72

Query: 75  CSEEMFLQFRMKIINLKLERFQDRVEFSGNPSKYDVSVMLRNVQPEDEGIYNCYIMNPPD 134
            S++    +   +    L  +++RVEF   PS  D ++ L  ++ EDEG+Y C     P 
Sbjct: 73  GSKQNVAIYNPSMGVSVLAPYRERVEFL-RPSFTDGTIRLSRLELEDEGVYICEFATFPT 131

Query: 135 RHRGHGKIHLQVLMEEPPERDSTVAVI 161
            +R   +++L V+ +     + T AV+
Sbjct: 132 GNR-ESQLNLTVMAKPTNWIEGTQAVL 157


>gi|42560231 poliovirus receptor-related 1 isoform 2 [Homo sapiens]
          Length = 458

 Score = 43.1 bits (100), Expect = 2e-04
 Identities = 42/147 (28%), Positives = 71/147 (48%), Gaps = 9/147 (6%)

Query: 16  GLSLFFSLVPPGRSMEVTVPATLNVLNGSDARLPCTF-NSCYTVNHKQFSLNWTYQECNN 74
           GL+ FF  +P   S  V V  ++    G+D  L C+F N   +V   Q     T+Q+  N
Sbjct: 19  GLTAFF--LPGVHSQVVQVNDSMYGFIGTDVVLHCSFANPLPSVKITQV----TWQKSTN 72

Query: 75  CSEEMFLQFRMKIINLKLERFQDRVEFSGNPSKYDVSVMLRNVQPEDEGIYNCYIMNPPD 134
            S++    +   +    L  +++RVEF   PS  D ++ L  ++ EDEG+Y C     P 
Sbjct: 73  GSKQNVAIYNPSMGVSVLAPYRERVEFL-RPSFTDGTIRLSRLELEDEGVYICEFATFPT 131

Query: 135 RHRGHGKIHLQVLMEEPPERDSTVAVI 161
            +R   +++L V+ +     + T AV+
Sbjct: 132 GNR-ESQLNLTVMAKPTNWIEGTQAVL 157


>gi|42560237 poliovirus receptor-related 1 isoform 1 [Homo sapiens]
          Length = 517

 Score = 43.1 bits (100), Expect = 2e-04
 Identities = 42/147 (28%), Positives = 71/147 (48%), Gaps = 9/147 (6%)

Query: 16  GLSLFFSLVPPGRSMEVTVPATLNVLNGSDARLPCTF-NSCYTVNHKQFSLNWTYQECNN 74
           GL+ FF  +P   S  V V  ++    G+D  L C+F N   +V   Q     T+Q+  N
Sbjct: 19  GLTAFF--LPGVHSQVVQVNDSMYGFIGTDVVLHCSFANPLPSVKITQV----TWQKSTN 72

Query: 75  CSEEMFLQFRMKIINLKLERFQDRVEFSGNPSKYDVSVMLRNVQPEDEGIYNCYIMNPPD 134
            S++    +   +    L  +++RVEF   PS  D ++ L  ++ EDEG+Y C     P 
Sbjct: 73  GSKQNVAIYNPSMGVSVLAPYRERVEFL-RPSFTDGTIRLSRLELEDEGVYICEFATFPT 131

Query: 135 RHRGHGKIHLQVLMEEPPERDSTVAVI 161
            +R   +++L V+ +     + T AV+
Sbjct: 132 GNR-ESQLNLTVMAKPTNWIEGTQAVL 157



 Score = 30.4 bits (67), Expect = 1.2
 Identities = 22/87 (25%), Positives = 34/87 (39%), Gaps = 13/87 (14%)

Query: 96  QDRVEFSGNPSKYDVSVMLRNVQPEDEGIYNCYIMNPPDRHRGHGKIHLQVL--MEEPPE 153
           Q+R  F   P  Y ++           G Y C   NP     G  ++++        PPE
Sbjct: 296 QNRTLFFKGPINYSLA-----------GTYICEATNPIGTRSGQVEVNITEFPYTPSPPE 344

Query: 154 RDSTVAVIVGASVGGFLAVVILVLMVV 180
                  +  A +GG    ++LVL+VV
Sbjct: 345 HGRRAGPVPTAIIGGVAGSILLVLIVV 371


>gi|4503173 coxsackie virus and adenovirus receptor precursor [Homo
           sapiens]
          Length = 365

 Score = 41.6 bits (96), Expect = 5e-04
 Identities = 37/135 (27%), Positives = 57/135 (42%), Gaps = 7/135 (5%)

Query: 19  LFFSLVPPGRSMEVTVPATL-NVLNGSDARLPCTFNSCYTVNHKQFSLNWTYQECNN--C 75
           L   +V   RS+ +T P  +     G  A LPC F +    +     + W     +N   
Sbjct: 9   LLCGVVDFARSLSITTPEEMIEKAKGETAYLPCKF-TLSPEDQGPLDIEWLISPADNQKV 67

Query: 76  SEEMFLQFRMKIINLKLERFQDRVEFSGNPSKY-DVSVMLRNVQPEDEGIYNCYIMNPPD 134
            + + L    KI +      + RV F+ N  K  D S+ + N+Q  D G Y C +   P 
Sbjct: 68  DQVIILYSGDKIYDDYYPDLKGRVHFTSNDLKSGDASINVTNLQLSDIGTYQCKVKKAPG 127

Query: 135 RHRGHGKIHLQVLME 149
               + KIHL VL++
Sbjct: 128 --VANKKIHLVVLVK 140


>gi|9055238 voltage-gated sodium channel beta-3 subunit precursor
           [Homo sapiens]
          Length = 215

 Score = 40.0 bits (92), Expect = 0.001
 Identities = 47/186 (25%), Positives = 85/186 (45%), Gaps = 20/186 (10%)

Query: 32  VTVPATLNVLNGSDARLPCTFNSCYTVNHKQFS--LNWTYQECNNCSEEMFLQFRMKIIN 89
           V VP+    + G+  +L C   SC      + +  + W Y+       + FL +  +  +
Sbjct: 27  VEVPSETEAVQGNPMKLRCI--SCMKREEVEATTVVEWFYRPEGG---KDFLIYEYRNGH 81

Query: 90  LKLER-FQDRVEFSGNPSKYDVSVMLRNVQPEDEGIYNCYIMN--PPDRHRGHGK----I 142
            ++E  FQ R++++G+    DVS+ + NV   D G+Y C +      + HR   K    I
Sbjct: 82  QEVESPFQGRLQWNGSKDLQDVSITVLNVTLNDSGLYTCNVSREFEFEAHRPFVKTTRLI 141

Query: 143 HLQVLMEEPPERDSTVAVIVGASVGGFLAVVILVLMVVKCVRR-----KKEQKLSTDDLK 197
            L+V  E   +  S V+ I+   +  FL + +L+ M+  C R+     +  Q+ ++D L 
Sbjct: 142 PLRVTEEAGEDFTSVVSEIMMYILLVFLTLWLLIEMIY-CYRKVSKAEEAAQENASDYLA 200

Query: 198 TEEEGK 203
              E K
Sbjct: 201 IPSENK 206


>gi|93587332 voltage-gated sodium channel beta-3 subunit precursor
           [Homo sapiens]
          Length = 215

 Score = 40.0 bits (92), Expect = 0.001
 Identities = 47/186 (25%), Positives = 85/186 (45%), Gaps = 20/186 (10%)

Query: 32  VTVPATLNVLNGSDARLPCTFNSCYTVNHKQFS--LNWTYQECNNCSEEMFLQFRMKIIN 89
           V VP+    + G+  +L C   SC      + +  + W Y+       + FL +  +  +
Sbjct: 27  VEVPSETEAVQGNPMKLRCI--SCMKREEVEATTVVEWFYRPEGG---KDFLIYEYRNGH 81

Query: 90  LKLER-FQDRVEFSGNPSKYDVSVMLRNVQPEDEGIYNCYIMN--PPDRHRGHGK----I 142
            ++E  FQ R++++G+    DVS+ + NV   D G+Y C +      + HR   K    I
Sbjct: 82  QEVESPFQGRLQWNGSKDLQDVSITVLNVTLNDSGLYTCNVSREFEFEAHRPFVKTTRLI 141

Query: 143 HLQVLMEEPPERDSTVAVIVGASVGGFLAVVILVLMVVKCVRR-----KKEQKLSTDDLK 197
            L+V  E   +  S V+ I+   +  FL + +L+ M+  C R+     +  Q+ ++D L 
Sbjct: 142 PLRVTEEAGEDFTSVVSEIMMYILLVFLTLWLLIEMIY-CYRKVSKAEEAAQENASDYLA 200

Query: 198 TEEEGK 203
              E K
Sbjct: 201 IPSENK 206


>gi|61966777 V-set and immunoglobulin domain containing 8 [Homo
           sapiens]
          Length = 414

 Score = 39.7 bits (91), Expect = 0.002
 Identities = 22/55 (40%), Positives = 31/55 (56%), Gaps = 2/55 (3%)

Query: 77  EEMFLQFRMKIINL-KLERFQDRVEFSGN-PSKYDVSVMLRNVQPEDEGIYNCYI 129
           E +FL ++ K IN   L   Q RV F+ + PS+YD S+ L N+Q  D   Y C +
Sbjct: 74  ENVFLSYQDKRINHGSLPHLQQRVRFAASDPSQYDASINLMNLQVSDTATYECRV 128



 Score = 29.3 bits (64), Expect = 2.6
 Identities = 20/84 (23%), Positives = 38/84 (45%), Gaps = 10/84 (11%)

Query: 95  FQDRVEFSGNPSKYDVSVMLRNVQPEDEGIYNCYIMNPPDRHRGHGKIHLQVLMEEPPER 154
           +Q+    S N    +  ++L+++   D+G+Y C + N          +   V + E    
Sbjct: 207 YQESFHSSINQGLNNGDLVLKDISRADDGLYQCTVAN---------NVGYSVCVVEVKVS 257

Query: 155 DS-TVAVIVGASVGGFLAVVILVL 177
           DS  + VI+G  +G  LA+  L +
Sbjct: 258 DSRRIGVIIGIVLGSLLALGCLAV 281


>gi|226529863 T-cell immunoglobulin and mucin domain containing 4
           isoform 1 [Homo sapiens]
          Length = 378

 Score = 38.9 bits (89), Expect = 0.003
 Identities = 26/103 (25%), Positives = 45/103 (43%), Gaps = 9/103 (8%)

Query: 32  VTVPATLNVLNGSDARLPCTFNSCYTVNHKQFSLNWTYQEC--NNCSEEMFLQFRMKIIN 89
           VT    +  + G    LPC ++S    +H   S+ W   +C  + C E +     M++ +
Sbjct: 22  VTSETVVTEVLGHRVTLPCLYSSW---SHNSNSMCWGKDQCPYSGCKEALIRTDGMRVTS 78

Query: 90  LKLERFQDRVEFSGNPSKYDVSVMLRNVQPEDEGIYNCYIMNP 132
            K  +++      G   + DVS+ + N    D G+Y C I  P
Sbjct: 79  RKSAKYR----LQGTIPRGDVSLTILNPSESDSGVYCCRIEVP 117


>gi|226498466 T-cell immunoglobulin and mucin domain containing 4
           isoform 2 [Homo sapiens]
          Length = 350

 Score = 38.9 bits (89), Expect = 0.003
 Identities = 26/103 (25%), Positives = 45/103 (43%), Gaps = 9/103 (8%)

Query: 32  VTVPATLNVLNGSDARLPCTFNSCYTVNHKQFSLNWTYQEC--NNCSEEMFLQFRMKIIN 89
           VT    +  + G    LPC ++S    +H   S+ W   +C  + C E +     M++ +
Sbjct: 22  VTSETVVTEVLGHRVTLPCLYSSW---SHNSNSMCWGKDQCPYSGCKEALIRTDGMRVTS 78

Query: 90  LKLERFQDRVEFSGNPSKYDVSVMLRNVQPEDEGIYNCYIMNP 132
            K  +++      G   + DVS+ + N    D G+Y C I  P
Sbjct: 79  RKSAKYR----LQGTIPRGDVSLTILNPSESDSGVYCCRIEVP 117


>gi|239753613 PREDICTED: similar to hCG1657343 [Homo sapiens]
          Length = 346

 Score = 38.1 bits (87), Expect = 0.006
 Identities = 30/126 (23%), Positives = 60/126 (47%), Gaps = 7/126 (5%)

Query: 59  NHKQFSLNWTYQECNNCSEEMFLQFRMKIINLKLER--FQDRVEFS-GNPSKYDVSVMLR 115
           ++K++ L + Y +      ++  QF      L+ +   ++ RV       S+  +S++LR
Sbjct: 115 DNKEYYLLFKYLDFFEVFSKLVYQFHNNTEQLEDQNSLYEGRVSVDQAEISEGTLSLLLR 174

Query: 116 NVQPEDEGIYNCYIMNPPDRHRGHGKIHLQVLMEEPPERDSTVAVIVGASVGGFLAVVIL 175
           NV   DE IY C  + P     G G+  +++++EE    + ++  I+   + GF  V  +
Sbjct: 175 NVDFMDEAIYKCSAITPD----GRGESTIKLIVEERDLSNHSIVEILEEQMNGFYRVFSI 230

Query: 176 VLMVVK 181
           +   VK
Sbjct: 231 LKYPVK 236


>gi|239748209 PREDICTED: similar to hCG1657343 [Homo sapiens]
          Length = 346

 Score = 38.1 bits (87), Expect = 0.006
 Identities = 30/126 (23%), Positives = 60/126 (47%), Gaps = 7/126 (5%)

Query: 59  NHKQFSLNWTYQECNNCSEEMFLQFRMKIINLKLER--FQDRVEFS-GNPSKYDVSVMLR 115
           ++K++ L + Y +      ++  QF      L+ +   ++ RV       S+  +S++LR
Sbjct: 115 DNKEYYLLFKYLDFFEVFSKLVYQFHNNTEQLEDQNSLYEGRVSVDQAEISEGTLSLLLR 174

Query: 116 NVQPEDEGIYNCYIMNPPDRHRGHGKIHLQVLMEEPPERDSTVAVIVGASVGGFLAVVIL 175
           NV   DE IY C  + P     G G+  +++++EE    + ++  I+   + GF  V  +
Sbjct: 175 NVDFMDEAIYKCSAITPD----GRGESTIKLIVEERDLSNHSIVEILEEQMNGFYRVFSI 230

Query: 176 VLMVVK 181
           +   VK
Sbjct: 231 LKYPVK 236


>gi|239742107 PREDICTED: similar to hCG1657343 [Homo sapiens]
          Length = 346

 Score = 38.1 bits (87), Expect = 0.006
 Identities = 30/126 (23%), Positives = 60/126 (47%), Gaps = 7/126 (5%)

Query: 59  NHKQFSLNWTYQECNNCSEEMFLQFRMKIINLKLER--FQDRVEFS-GNPSKYDVSVMLR 115
           ++K++ L + Y +      ++  QF      L+ +   ++ RV       S+  +S++LR
Sbjct: 115 DNKEYYLLFKYLDFFEVFSKLVYQFHNNTEQLEDQNSLYEGRVSVDQAEISEGTLSLLLR 174

Query: 116 NVQPEDEGIYNCYIMNPPDRHRGHGKIHLQVLMEEPPERDSTVAVIVGASVGGFLAVVIL 175
           NV   DE IY C  + P     G G+  +++++EE    + ++  I+   + GF  V  +
Sbjct: 175 NVDFMDEAIYKCSAITPD----GRGESTIKLIVEERDLSNHSIVEILEEQMNGFYRVFSI 230

Query: 176 VLMVVK 181
           +   VK
Sbjct: 231 LKYPVK 236


>gi|222136611 poliovirus receptor-related 4 [Homo sapiens]
          Length = 510

 Score = 38.1 bits (87), Expect = 0.006
 Identities = 39/150 (26%), Positives = 64/150 (42%), Gaps = 14/150 (9%)

Query: 4   DAWLPRPAFSLTGLSLFFSLVPPGRSMEVTVPATLNVLNGSDARLPCTFNSCYTVNHKQF 63
           +AWL      L  L+ F    P G   E+     + V+ G DA+LPC +        +  
Sbjct: 13  EAWL----LLLLLLASFTGRCPAG---ELETSDVVTVVLGQDAKLPCFYRG--DSGEQVG 63

Query: 64  SLNWTYQECNNCSEEMFLQFRMKIINLKLERFQDRVEFSGNP-SKYDVSVMLRNVQPEDE 122
            + W   +    ++E+ L      +++    ++ RVE    P +  D SV+LRN    DE
Sbjct: 64  QVAWARVDAGEGAQELALLHSKYGLHVS-PAYEGRVEQPPPPRNPLDGSVLLRNAVQADE 122

Query: 123 GIYNCYIMNPPDRHRGHGKIHLQVLMEEPP 152
           G Y C +   P    G  +  L++ +  PP
Sbjct: 123 GEYECRVSTFP---AGSFQARLRLRVLVPP 149


>gi|5031561 transmembrane glycoprotein A33 precursor [Homo sapiens]
          Length = 319

 Score = 38.1 bits (87), Expect = 0.006
 Identities = 26/117 (22%), Positives = 51/117 (43%), Gaps = 4/117 (3%)

Query: 38  LNVLNGSDARLPCTFNSCYTVNHKQFSLNWTYQECNNCSEEMFLQFRMKIINLKLERFQD 97
           L    G    LPCT+++  + + ++  + W      +    +   F  K   +  E +++
Sbjct: 31  LRASQGKSVTLPCTYHT--STSSREGLIQWDKLLLTHTERVVIWPFSNKNY-IHGELYKN 87

Query: 98  RVEFSGNPSKYDVSVMLRNVQPEDEGIYNCYIMNPPDRHRGHGKIHLQVLMEEPPER 154
           RV  S N  + D S+ +  +   D G Y C +    D   G+ K  +++L+  PP +
Sbjct: 88  RVSISNNAEQSDASITIDQLTMADNGTYECSVSLMSDL-EGNTKSRVRLLVLVPPSK 143


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.136    0.414 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,433,774
Number of Sequences: 37866
Number of extensions: 419961
Number of successful extensions: 1976
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 68
Number of HSP's successfully gapped in prelim test: 113
Number of HSP's that attempted gapping in prelim test: 1789
Number of HSP's gapped (non-prelim): 283
length of query: 215
length of database: 18,247,518
effective HSP length: 98
effective length of query: 117
effective length of database: 14,536,650
effective search space: 1700788050
effective search space used: 1700788050
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 60 (27.7 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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