Search of human proteins with 4758766

Search of human proteins with 4758766

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4758766 N-deacetylase/N-sulfotransferase (heparan
glucosaminyl) 3 [Homo sapiens]
         (873 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4758766 N-deacetylase/N-sulfotransferase (heparan glucosaminy...  1809   0.0  
gi|12007650 heparan sulfate N-deacetylase/N-sulfotransferase 4 [...  1520   0.0  
gi|4505351 N-deacetylase/N-sulfotransferase (heparan glucosaminy...  1318   0.0  
gi|4505353 heparan glucosaminyl N-deacetylase/N-sulfotransferase...  1232   0.0  
gi|104876423 heparan sulfate D-glucosaminyl 3-O-sulfotransferase...   131   2e-30
gi|5174463 heparan sulfate D-glucosaminyl  3-O-sulfotransferase ...   129   9e-30
gi|45267824 heparan sulfate (glucosamine) 3-O-sulfotransferase 5...   128   2e-29
gi|5174467 heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3...   128   3e-29
gi|5174465 heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3...   128   3e-29
gi|4826764 heparan sulfate D-glucosaminyl 3-O-sulfotransferase 1...   128   3e-29
gi|116089312 heparan sulfate (glucosamine) 3-O-sulfotransferase ...   124   4e-28
gi|45505173 B cell RAG associated protein [Homo sapiens]               47   8e-05
gi|56847626 sulfotransferase family, cytosolic, 1C, member 3 [Ho...    34   0.52 
gi|4557481 ATP-binding cassette, sub-family C (CFTR/MRP), member...    32   2.0  
gi|7657633 sulfotransferase family 4A, member 1 [Homo sapiens]         32   3.4  
gi|33350932 cytoplasmic dynein 1 heavy chain 1 [Homo sapiens]          32   3.4  
gi|190014581 leucine rich repeat containing 2 [Homo sapiens]           32   3.4  
gi|27545328 leucine rich repeat containing 2 [Homo sapiens]            32   3.4  
gi|45446740 ATP-binding cassette, sub-family A, member 2 isoform...    31   4.4  
gi|47078218 ATP-binding cassette, sub-family A, member 2 isoform...    31   4.4  
gi|116517224 coiled-coil domain containing 144B [Homo sapiens]         31   4.4  
gi|62868225 aryl sulfotransferase [Homo sapiens]                       31   5.7  
gi|62868223 aryl sulfotransferase [Homo sapiens]                       31   5.7  
gi|29550921 sulfotransferase family, cytosolic, 1A, phenol-prefe...    31   5.7  
gi|10835035 sulfotransferase family, cytosolic, 1A, phenol-prefe...    31   5.7  
gi|197333706 leucine rich repeat containing 8 family, member D [...    30   7.5  
gi|34222199 leucine rich repeat containing 8 family, member D [H...    30   7.5  
gi|166999223 glutamate receptor, metabotropic 1 isoform beta pre...    30   9.8  
gi|166999098 glutamate receptor, metabotropic 1 isoform alpha pr...    30   9.8  

>gi|4758766 N-deacetylase/N-sulfotransferase (heparan glucosaminyl)
           3 [Homo sapiens]
          Length = 873

 Score = 1809 bits (4685), Expect = 0.0
 Identities = 873/873 (100%), Positives = 873/873 (100%)

Query: 1   MSFIMKLHRHFQRTVILLATFCMVSIIISAYYLYSGYKQENELSETASEVDCGDLQHLPY 60
           MSFIMKLHRHFQRTVILLATFCMVSIIISAYYLYSGYKQENELSETASEVDCGDLQHLPY
Sbjct: 1   MSFIMKLHRHFQRTVILLATFCMVSIIISAYYLYSGYKQENELSETASEVDCGDLQHLPY 60

Query: 61  QLMEVKAMKLFDASRTDPTVLVFVESQYSSLGQDIIMILESSRFQYHIEIAPGKGDLPVL 120
           QLMEVKAMKLFDASRTDPTVLVFVESQYSSLGQDIIMILESSRFQYHIEIAPGKGDLPVL
Sbjct: 61  QLMEVKAMKLFDASRTDPTVLVFVESQYSSLGQDIIMILESSRFQYHIEIAPGKGDLPVL 120

Query: 121 IDKMKGKYILIIYENILKYINMDSWNRSLLDKYCVEYGVGVIGFHKTSEKSVQSFQLKGF 180
           IDKMKGKYILIIYENILKYINMDSWNRSLLDKYCVEYGVGVIGFHKTSEKSVQSFQLKGF
Sbjct: 121 IDKMKGKYILIIYENILKYINMDSWNRSLLDKYCVEYGVGVIGFHKTSEKSVQSFQLKGF 180

Query: 181 PFSIYGNLAVKDCCINPHSPLIRVTKSSKLEKGSLPGTDWTVFQINHSAYQPVIFAKVKT 240
           PFSIYGNLAVKDCCINPHSPLIRVTKSSKLEKGSLPGTDWTVFQINHSAYQPVIFAKVKT
Sbjct: 181 PFSIYGNLAVKDCCINPHSPLIRVTKSSKLEKGSLPGTDWTVFQINHSAYQPVIFAKVKT 240

Query: 241 PENLSPSISKGAFYATIIHDLGLHDGIQRVLFGNNLNFWLHKLIFIDAISFLSGKRLTLS 300
           PENLSPSISKGAFYATIIHDLGLHDGIQRVLFGNNLNFWLHKLIFIDAISFLSGKRLTLS
Sbjct: 241 PENLSPSISKGAFYATIIHDLGLHDGIQRVLFGNNLNFWLHKLIFIDAISFLSGKRLTLS 300

Query: 301 LDRYILVDIDDIFVGKEGTRMNTNDVKALLDTQNLLRAQITNFTFNLGFSGKFYHTGTEE 360
           LDRYILVDIDDIFVGKEGTRMNTNDVKALLDTQNLLRAQITNFTFNLGFSGKFYHTGTEE
Sbjct: 301 LDRYILVDIDDIFVGKEGTRMNTNDVKALLDTQNLLRAQITNFTFNLGFSGKFYHTGTEE 360

Query: 361 EDEGDDCLLGSVDEFWWFPHMWSHMQPHLFHNESSLVEQMILNKKFALEHGIPTDMGYAV 420
           EDEGDDCLLGSVDEFWWFPHMWSHMQPHLFHNESSLVEQMILNKKFALEHGIPTDMGYAV
Sbjct: 361 EDEGDDCLLGSVDEFWWFPHMWSHMQPHLFHNESSLVEQMILNKKFALEHGIPTDMGYAV 420

Query: 421 APHHSGVYPVHVQLYEAWKKVWNIKITSTEEYPHLKPARYRRGFIHKNIMVLPRQTCGLF 480
           APHHSGVYPVHVQLYEAWKKVWNIKITSTEEYPHLKPARYRRGFIHKNIMVLPRQTCGLF
Sbjct: 421 APHHSGVYPVHVQLYEAWKKVWNIKITSTEEYPHLKPARYRRGFIHKNIMVLPRQTCGLF 480

Query: 481 THTIFYKEYPGGPKELDKSIQGGELFFTVVLNPISIFMTHLSNYGNDRLGLYTFVNLANF 540
           THTIFYKEYPGGPKELDKSIQGGELFFTVVLNPISIFMTHLSNYGNDRLGLYTFVNLANF
Sbjct: 481 THTIFYKEYPGGPKELDKSIQGGELFFTVVLNPISIFMTHLSNYGNDRLGLYTFVNLANF 540

Query: 541 VKSWTNLRLQTLPPVQLAHKYFELFPDQKDPLWQNPCDDKRHRDIWSKEKTCDRLPKFLV 600
           VKSWTNLRLQTLPPVQLAHKYFELFPDQKDPLWQNPCDDKRHRDIWSKEKTCDRLPKFLV
Sbjct: 541 VKSWTNLRLQTLPPVQLAHKYFELFPDQKDPLWQNPCDDKRHRDIWSKEKTCDRLPKFLV 600

Query: 601 IGPQKTGTTALYLFLVMHPSILSNSPSPKTFEEVQFFNRNNYHRGIDWYMDFFPVPSNVT 660
           IGPQKTGTTALYLFLVMHPSILSNSPSPKTFEEVQFFNRNNYHRGIDWYMDFFPVPSNVT
Sbjct: 601 IGPQKTGTTALYLFLVMHPSILSNSPSPKTFEEVQFFNRNNYHRGIDWYMDFFPVPSNVT 660

Query: 661 TDFLFEKSANYFHSEEAPKRAASLVPKAKIITILIDPSDRAYSWYQHQRSHEDPAALKFS 720
           TDFLFEKSANYFHSEEAPKRAASLVPKAKIITILIDPSDRAYSWYQHQRSHEDPAALKFS
Sbjct: 661 TDFLFEKSANYFHSEEAPKRAASLVPKAKIITILIDPSDRAYSWYQHQRSHEDPAALKFS 720

Query: 721 FYEVISAGPRAPSELRALQKRCLVPGWYASHIERWLVYFPPFQLLIIDGQQLRTDPATVM 780
           FYEVISAGPRAPSELRALQKRCLVPGWYASHIERWLVYFPPFQLLIIDGQQLRTDPATVM
Sbjct: 721 FYEVISAGPRAPSELRALQKRCLVPGWYASHIERWLVYFPPFQLLIIDGQQLRTDPATVM 780

Query: 781 DEVQKFLGVLPHYNYSEALTFDSHKGFWCQLLEEGKTKCLGKSKGRKYPPMDSDSRTFLS 840
           DEVQKFLGVLPHYNYSEALTFDSHKGFWCQLLEEGKTKCLGKSKGRKYPPMDSDSRTFLS
Sbjct: 781 DEVQKFLGVLPHYNYSEALTFDSHKGFWCQLLEEGKTKCLGKSKGRKYPPMDSDSRTFLS 840

Query: 841 SYYRDHNVELSKLLHKLGQPLPSWLRQELQKVR 873
           SYYRDHNVELSKLLHKLGQPLPSWLRQELQKVR
Sbjct: 841 SYYRDHNVELSKLLHKLGQPLPSWLRQELQKVR 873


>gi|12007650 heparan sulfate N-deacetylase/N-sulfotransferase 4
           [Homo sapiens]
          Length = 872

 Score = 1520 bits (3936), Expect = 0.0
 Identities = 712/873 (81%), Positives = 790/873 (90%), Gaps = 1/873 (0%)

Query: 1   MSFIMKLHRHFQRTVILLATFCMVSIIISAYYLYSGYKQENELSETASEVDCGDLQHLPY 60
           M+ I+KL R F+  ++LLATFC+VSI+ISAY+LYSGYKQE  L ET +E +C D++ LPY
Sbjct: 1   MNLIVKLRRSFRTLIVLLATFCLVSIVISAYFLYSGYKQEMTLIETTAEAECTDIKILPY 60

Query: 61  QLMEVKAMKLFDASRTDPTVLVFVESQYSSLGQDIIMILESSRFQYHIEIAPGKGDLPVL 120
           + ME+K +K  D S+TDPTVL+FVESQYS LGQDII ILESSRFQYH+ IAPGKGD+P L
Sbjct: 61  RSMELKTVKPIDTSKTDPTVLLFVESQYSQLGQDIIAILESSRFQYHMVIAPGKGDIPPL 120

Query: 121 IDKMKGKYILIIYENILKYINMDSWNRSLLDKYCVEYGVGVIGFHKTSEKSVQSFQLKGF 180
            D  KGKY L+IYENILKY++MDSWNR LL+KYCVEY V +IGFHK +E S+ S QLKGF
Sbjct: 121 TDNGKGKYTLVIYENILKYVSMDSWNRELLEKYCVEYSVSIIGFHKANENSLPSTQLKGF 180

Query: 181 PFSIYGNLAVKDCCINPHSPLIRVTKSSKLEKGSLPGTDWTVFQINHSAYQPVIFAKVKT 240
           P +++ NLA+KDC +NP SPL+ +TK+ K+EKG LPG DWT+FQ NHS YQPV+  +++T
Sbjct: 181 PLNLFNNLALKDCFVNPQSPLLHITKAPKVEKGPLPGEDWTIFQYNHSTYQPVLLTELQT 240

Query: 241 PENLSPSISKGAFYATIIHDLGLHDGIQRVLFGNNLNFWLHKLIFIDAISFLSGKRLTLS 300
            ++LS S+S    +AT+I DLGLHDGIQRVLFGNNLNFWLHKLIFIDAISFLSGKRLTLS
Sbjct: 241 EKSLS-SLSSKTLFATVIQDLGLHDGIQRVLFGNNLNFWLHKLIFIDAISFLSGKRLTLS 299

Query: 301 LDRYILVDIDDIFVGKEGTRMNTNDVKALLDTQNLLRAQITNFTFNLGFSGKFYHTGTEE 360
           LDRYILVDIDDIFVGKEGTRMN  DVKALL+TQNLLR Q+ NFTFNLGFSGKFYHTGTEE
Sbjct: 300 LDRYILVDIDDIFVGKEGTRMNVKDVKALLETQNLLRTQVANFTFNLGFSGKFYHTGTEE 359

Query: 361 EDEGDDCLLGSVDEFWWFPHMWSHMQPHLFHNESSLVEQMILNKKFALEHGIPTDMGYAV 420
           EDEGDD LL SVDEFWWFPHMWSHMQPHLFHNESSLVEQMILNK+FALEHGIP +MGYAV
Sbjct: 360 EDEGDDLLLRSVDEFWWFPHMWSHMQPHLFHNESSLVEQMILNKEFALEHGIPINMGYAV 419

Query: 421 APHHSGVYPVHVQLYEAWKKVWNIKITSTEEYPHLKPARYRRGFIHKNIMVLPRQTCGLF 480
           APHHSGVYPVH+QLY AWKKVW I++TSTEEYPHLKPARYR+GFIH +IMVLPRQTCGLF
Sbjct: 420 APHHSGVYPVHIQLYAAWKKVWGIQVTSTEEYPHLKPARYRKGFIHNSIMVLPRQTCGLF 479

Query: 481 THTIFYKEYPGGPKELDKSIQGGELFFTVVLNPISIFMTHLSNYGNDRLGLYTFVNLANF 540
           THTIFYKEYPGGP+ELDKSI+GGELF T++LNPISIFMTHLSNYGNDRLGLYTFVNL NF
Sbjct: 480 THTIFYKEYPGGPQELDKSIRGGELFLTILLNPISIFMTHLSNYGNDRLGLYTFVNLVNF 539

Query: 541 VKSWTNLRLQTLPPVQLAHKYFELFPDQKDPLWQNPCDDKRHRDIWSKEKTCDRLPKFLV 600
           V+SWTNL+LQTLPPVQLAH+YFELFP+QKDPLWQNPCDDKRH+DIWS+EKTCD LPKFLV
Sbjct: 540 VQSWTNLKLQTLPPVQLAHQYFELFPEQKDPLWQNPCDDKRHKDIWSREKTCDHLPKFLV 599

Query: 601 IGPQKTGTTALYLFLVMHPSILSNSPSPKTFEEVQFFNRNNYHRGIDWYMDFFPVPSNVT 660
           IGPQKTGTTALYLFL+MHPSI+SN PSPKTFEEVQFFN NNYH+GIDWYMDFFP PSN T
Sbjct: 600 IGPQKTGTTALYLFLLMHPSIISNLPSPKTFEEVQFFNGNNYHKGIDWYMDFFPTPSNTT 659

Query: 661 TDFLFEKSANYFHSEEAPKRAASLVPKAKIITILIDPSDRAYSWYQHQRSHEDPAALKFS 720
           +DFLFEKSANYFHSEEAP+RAASLVPKAKIITILIDPSDRAYSWYQHQRSHEDPAAL+F+
Sbjct: 660 SDFLFEKSANYFHSEEAPRRAASLVPKAKIITILIDPSDRAYSWYQHQRSHEDPAALRFN 719

Query: 721 FYEVISAGPRAPSELRALQKRCLVPGWYASHIERWLVYFPPFQLLIIDGQQLRTDPATVM 780
           FYEVIS G  APS+L+ LQ+RCLVPGWYA HIERWL YF   QLLIIDGQQLR+DPATVM
Sbjct: 720 FYEVISTGHWAPSDLKTLQRRCLVPGWYAVHIERWLTYFATSQLLIIDGQQLRSDPATVM 779

Query: 781 DEVQKFLGVLPHYNYSEALTFDSHKGFWCQLLEEGKTKCLGKSKGRKYPPMDSDSRTFLS 840
           DEVQKFLGV P YNYSEALTFD  KGFWCQLLE GKTKCLGKSKGRKYPPMD +SRTFLS
Sbjct: 780 DEVQKFLGVTPRYNYSEALTFDPQKGFWCQLLEGGKTKCLGKSKGRKYPPMDPESRTFLS 839

Query: 841 SYYRDHNVELSKLLHKLGQPLPSWLRQELQKVR 873
           +YYRDHNVELSKLLH+LGQPLPSWLRQELQKVR
Sbjct: 840 NYYRDHNVELSKLLHRLGQPLPSWLRQELQKVR 872


>gi|4505351 N-deacetylase/N-sulfotransferase (heparan glucosaminyl)
           1 [Homo sapiens]
          Length = 882

 Score = 1318 bits (3411), Expect = 0.0
 Identities = 622/881 (70%), Positives = 730/881 (82%), Gaps = 10/881 (1%)

Query: 1   MSFIMKLHRHF--QRTVILLATFCMVSIIISAYYLYSGYKQENELSETASEVDCGDLQHL 58
           ++ + +L RH   Q  + LL  FC+ S+ ISAYYLY G+K+  E S  A E DCGD   +
Sbjct: 4   LACLRRLCRHVSPQAVLFLLFIFCLFSVFISAYYLY-GWKRGLEPSADAPEPDCGDPPPV 62

Query: 59  -PYQLMEVKAMKLFDASRTDPTVLVFVESQYSSLGQDIIMILESSRFQYHIEIAPGKGDL 117
            P +L+ +K ++    SRTDP VLVFVES YS LGQ+++ ILESSRF+Y  EIAPGKGD+
Sbjct: 63  APSRLLPLKPVQAATPSRTDPLVLVFVESLYSQLGQEVVAILESSRFKYRTEIAPGKGDM 122

Query: 118 PVLIDKMKGKYILIIYENILKYINMDSWNRSLLDKYCVEYGVGVIGFHKTSEKSVQSFQL 177
           P L DK +G++ LIIYENILKY+N+D+WNR LLDKYCV YGVG+IGF K +E S+ S QL
Sbjct: 123 PTLTDKGRGRFALIIYENILKYVNLDAWNRELLDKYCVAYGVGIIGFFKANENSLLSAQL 182

Query: 178 KGFPFSIYGNLAVKDCCINPHSPLIRVTKSSKLEKGSLPGTDWTVFQINHSAYQPVIFAK 237
           KGFP  ++ NL +KDC INP SPL+ VT+ S++EKG LPG DWTVFQ NHS Y+PV+ AK
Sbjct: 183 KGFPLFLHSNLGLKDCSINPKSPLLYVTRPSEVEKGVLPGEDWTVFQSNHSTYEPVLLAK 242

Query: 238 VKTPENLSPSISK-----GAFYATIIHDLGLHDGIQRVLFGNNLNFWLHKLIFIDAISFL 292
            ++ E++ P +        A +AT++ DLGLHDGIQRVLFGNNLNFWLHKL+F+DA++FL
Sbjct: 243 TRSSESI-PHLGADAGLHAALHATVVQDLGLHDGIQRVLFGNNLNFWLHKLVFVDAVAFL 301

Query: 293 SGKRLTLSLDRYILVDIDDIFVGKEGTRMNTNDVKALLDTQNLLRAQITNFTFNLGFSGK 352
           +GKRL+L LDRYILVDIDDIFVGKEGTRM   DVKAL DTQN LRA I NFTFNLG+SGK
Sbjct: 302 TGKRLSLPLDRYILVDIDDIFVGKEGTRMKVEDVKALFDTQNELRAHIPNFTFNLGYSGK 361

Query: 353 FYHTGTEEEDEGDDCLLGSVDEFWWFPHMWSHMQPHLFHNESSLVEQMILNKKFALEHGI 412
           F+HTGT  ED GDD LL  V EFWWFPHMWSHMQPHLFHN+S L EQM LNKKFA+EHGI
Sbjct: 362 FFHTGTNAEDAGDDLLLSYVKEFWWFPHMWSHMQPHLFHNQSVLAEQMALNKKFAVEHGI 421

Query: 413 PTDMGYAVAPHHSGVYPVHVQLYEAWKKVWNIKITSTEEYPHLKPARYRRGFIHKNIMVL 472
           PTDMGYAVAPHHSGVYPVHVQLYEAWK+VW+I++TSTEEYPHLKPARYRRGFIH  IMVL
Sbjct: 422 PTDMGYAVAPHHSGVYPVHVQLYEAWKQVWSIRVTSTEEYPHLKPARYRRGFIHNGIMVL 481

Query: 473 PRQTCGLFTHTIFYKEYPGGPKELDKSIQGGELFFTVVLNPISIFMTHLSNYGNDRLGLY 532
           PRQTCGLFTHTIFY EYPGG  ELDK I GGELF TV+LNPISIFMTHLSNYGNDRLGLY
Sbjct: 482 PRQTCGLFTHTIFYNEYPGGSSELDKIINGGELFLTVLLNPISIFMTHLSNYGNDRLGLY 541

Query: 533 TFVNLANFVKSWTNLRLQTLPPVQLAHKYFELFPDQKDPLWQNPCDDKRHRDIWSKEKTC 592
           TF +L  F+ SWTNLRLQTLPPVQLA KYF++F ++KDPLWQ+PC+DKRH+DIWSKEKTC
Sbjct: 542 TFKHLVRFLHSWTNLRLQTLPPVQLAQKYFQIFSEEKDPLWQDPCEDKRHKDIWSKEKTC 601

Query: 593 DRLPKFLVIGPQKTGTTALYLFLVMHPSILSNSPSPKTFEEVQFFNRNNYHRGIDWYMDF 652
           DR PK L+IGPQKTGTTALYLFL MHP + SN PS +TFEE+QFFN +NYH+GIDWYM+F
Sbjct: 602 DRFPKLLIIGPQKTGTTALYLFLGMHPDLSSNYPSSETFEEIQFFNGHNYHKGIDWYMEF 661

Query: 653 FPVPSNVTTDFLFEKSANYFHSEEAPKRAASLVPKAKIITILIDPSDRAYSWYQHQRSHE 712
           FP+PSN T+DF FEKSANYF SE AP+RAA+L+PKAK++TILI+P+DRAYSWYQHQR+H+
Sbjct: 662 FPIPSNTTSDFYFEKSANYFDSEVAPRRAAALLPKAKVLTILINPADRAYSWYQHQRAHD 721

Query: 713 DPAALKFSFYEVISAGPRAPSELRALQKRCLVPGWYASHIERWLVYFPPFQLLIIDGQQL 772
           DP ALK++F+EVI+AG  A S+LRALQ RCLVPGWYA+HIERWL  +   Q+L++DG+ L
Sbjct: 722 DPVALKYTFHEVITAGSDASSKLRALQNRCLVPGWYATHIERWLSAYHANQILVLDGKLL 781

Query: 773 RTDPATVMDEVQKFLGVLPHYNYSEALTFDSHKGFWCQLLEEGKTKCLGKSKGRKYPPMD 832
           RT+PA VMD VQKFLGV    +Y + L FD  KGFWCQLLE GKTKCLGKSKGRKYP MD
Sbjct: 782 RTEPAKVMDMVQKFLGVTNTIDYHKTLAFDPKKGFWCQLLEGGKTKCLGKSKGRKYPEMD 841

Query: 833 SDSRTFLSSYYRDHNVELSKLLHKLGQPLPSWLRQELQKVR 873
            DSR FL  YYRDHN+ELSKLL+K+GQ LP+WLR++LQ  R
Sbjct: 842 LDSRAFLKDYYRDHNIELSKLLYKMGQTLPTWLREDLQNTR 882


>gi|4505353 heparan glucosaminyl N-deacetylase/N-sulfotransferase 2
           [Homo sapiens]
          Length = 883

 Score = 1232 bits (3188), Expect = 0.0
 Identities = 567/861 (65%), Positives = 693/861 (80%), Gaps = 3/861 (0%)

Query: 13  RTVILLATFCMVSIIISAYYLYSGYKQENELSETASEVDCGDLQHLPYQLMEV--KAMKL 70
           R ++LL  F + S+   AYY+ +  K +  L     +   G           V  +  + 
Sbjct: 18  RLILLLIAFSLGSMGFLAYYVSTSPKAKEPLPLPLGDCSSGGAAGPGPARPPVPPRPPRP 77

Query: 71  FDASRTDPTVLVFVESQYSSLGQDIIMILESSRFQYHIEIAPGKGDLPVLIDKMKGKYIL 130
            + +RT+P VLVFVES YS LGQ+I+ ILESSRF+Y  E+APG+GD+P L D   G+Y+L
Sbjct: 78  PETARTEPVVLVFVESAYSQLGQEIVAILESSRFRYSTELAPGRGDMPTLTDNTHGRYVL 137

Query: 131 IIYENILKYINMDSWNRSLLDKYCVEYGVGVIGFHKTSEKSVQSFQLKGFPFSIYGNLAV 190
           +IYEN+LKY+N+D+W+R LLD+YCVEYGVG+IGF +  E S+ S QLKGFP  ++ NL +
Sbjct: 138 VIYENLLKYVNLDAWSRELLDRYCVEYGVGIIGFFRAHEHSLLSAQLKGFPLFLHSNLGL 197

Query: 191 KDCCINPHSPLIRVTKSSKLEKGSLPGTDWTVFQINHSAYQPVIFAKVKTPENLSPS-IS 249
           +D  +NP +PL+ +T+ S+LE G LPG DWT+FQ NHS Y+PV+ A ++  E   P  + 
Sbjct: 198 RDYQVNPSAPLLHLTRPSRLEPGPLPGDDWTIFQSNHSTYEPVLLASLRPAEPAVPGPVL 257

Query: 250 KGAFYATIIHDLGLHDGIQRVLFGNNLNFWLHKLIFIDAISFLSGKRLTLSLDRYILVDI 309
           + A   T++ DLGLHDGIQRVLFG+ L+FWLHKLIF+DA+++L+GKRL L LDRYILVDI
Sbjct: 258 RRARLPTVVQDLGLHDGIQRVLFGHGLSFWLHKLIFVDAVAYLTGKRLCLDLDRYILVDI 317

Query: 310 DDIFVGKEGTRMNTNDVKALLDTQNLLRAQITNFTFNLGFSGKFYHTGTEEEDEGDDCLL 369
           DDIFVGKEGTRM   DV+ALL TQN LR  + NFTFNLGFSGKFYHTGTEEED GDD LL
Sbjct: 318 DDIFVGKEGTRMKVADVEALLTTQNKLRTLVPNFTFNLGFSGKFYHTGTEEEDAGDDMLL 377

Query: 370 GSVDEFWWFPHMWSHMQPHLFHNESSLVEQMILNKKFALEHGIPTDMGYAVAPHHSGVYP 429
               EFWWFPHMWSHMQPHLFHN S L +QM LNK+FALEHGIPTD+GYAVAPHHSGVYP
Sbjct: 378 KHRKEFWWFPHMWSHMQPHLFHNRSVLADQMRLNKQFALEHGIPTDLGYAVAPHHSGVYP 437

Query: 430 VHVQLYEAWKKVWNIKITSTEEYPHLKPARYRRGFIHKNIMVLPRQTCGLFTHTIFYKEY 489
           +H QLYEAWK VW I++TSTEEYPHL+PARYRRGFIH  IMVLPRQTCGLFTHTIFY EY
Sbjct: 438 IHTQLYEAWKSVWGIQVTSTEEYPHLRPARYRRGFIHNGIMVLPRQTCGLFTHTIFYNEY 497

Query: 490 PGGPKELDKSIQGGELFFTVVLNPISIFMTHLSNYGNDRLGLYTFVNLANFVKSWTNLRL 549
           PGG +ELD+SI+GGELF TV+LNPISIFMTHLSNYGNDRLGLYTF +L  F++ WT LRL
Sbjct: 498 PGGSRELDRSIRGGELFLTVLLNPISIFMTHLSNYGNDRLGLYTFESLVRFLQCWTRLRL 557

Query: 550 QTLPPVQLAHKYFELFPDQKDPLWQNPCDDKRHRDIWSKEKTCDRLPKFLVIGPQKTGTT 609
           QTLPPV LA KYFELFP ++ PLWQNPCDDKRH+DIWSKEKTCDRLPKFL++GPQKTGTT
Sbjct: 558 QTLPPVPLAQKYFELFPQERSPLWQNPCDDKRHKDIWSKEKTCDRLPKFLIVGPQKTGTT 617

Query: 610 ALYLFLVMHPSILSNSPSPKTFEEVQFFNRNNYHRGIDWYMDFFPVPSNVTTDFLFEKSA 669
           A++ FL +HP++ S+ PSP TFEE+QFFN  NYH+GIDWYMDFFPVPSN +TDFLFEKSA
Sbjct: 618 AIHFFLSLHPAVTSSFPSPSTFEEIQFFNSPNYHKGIDWYMDFFPVPSNASTDFLFEKSA 677

Query: 670 NYFHSEEAPKRAASLVPKAKIITILIDPSDRAYSWYQHQRSHEDPAALKFSFYEVISAGP 729
            YF SE  P+R A+L+P+AKIIT+L +P+DRAYSWYQHQR+H DP AL ++FY+VISA  
Sbjct: 678 TYFDSEVVPRRGAALLPRAKIITVLTNPADRAYSWYQHQRAHGDPVALNYTFYQVISASS 737

Query: 730 RAPSELRALQKRCLVPGWYASHIERWLVYFPPFQLLIIDGQQLRTDPATVMDEVQKFLGV 789
           + P  LR+LQ RCLVPG+Y++H++RWL Y+P  QLLI+DGQ+LRT+PA  M+ +QKFLG+
Sbjct: 738 QTPLALRSLQNRCLVPGYYSTHLQRWLTYYPSGQLLIVDGQELRTNPAASMESIQKFLGI 797

Query: 790 LPHYNYSEALTFDSHKGFWCQLLEEGKTKCLGKSKGRKYPPMDSDSRTFLSSYYRDHNVE 849
            P  NY+  L FD  KGFWCQ LE GKT+CLG+SKGR+YP MD++SR FL+ ++R+HN+E
Sbjct: 798 TPFLNYTRTLRFDDDKGFWCQGLEGGKTRCLGRSKGRRYPDMDTESRLFLTDFFRNHNLE 857

Query: 850 LSKLLHKLGQPLPSWLRQELQ 870
           LSKLL +LGQP+PSWLR+ELQ
Sbjct: 858 LSKLLSRLGQPVPSWLREELQ 878


>gi|104876423 heparan sulfate D-glucosaminyl 3-O-sulfotransferase 4
           [Homo sapiens]
          Length = 456

 Score =  131 bits (330), Expect = 2e-30
 Identities = 88/257 (34%), Positives = 133/257 (51%), Gaps = 17/257 (6%)

Query: 594 RLPKFLVIGPQKTGTTALYLFLVMHPSILSNSPSPKTFEEVQFFNRNNYHRGIDWYMDFF 653
           +LP+ L+IG +K GT AL   + +HP + +    P       FF+RN Y +G++WY +  
Sbjct: 196 KLPQALIIGVKKGGTRALLEAIRVHPDVRAVGVEP------HFFDRN-YEKGLEWYRNV- 247

Query: 654 PVPSNVTTDFLFEKSANYFHSEEAPKRAASLVPKAKIITILIDPSDRAYSWYQHQRSHED 713
            +P  +      EK+ +YF + EAPKR  S+    K+I ++ +P  RA S Y    S + 
Sbjct: 248 -MPKTLDGQITMEKTPSYFVTNEAPKRIHSMAKDIKLIVVVRNPVTRAISDYTQTLSKKP 306

Query: 714 PAALKFSFYEVISAGPRAPSELRALQKRCLVPGWYASHIERWLVYFPPFQLLIIDGQQLR 773
               +   +EV++   R    + A      + G YA H+E WL YFP  Q+L + G++L 
Sbjct: 307 ----EIPTFEVLAFKNRTLGLIDASWSAIRI-GIYALHLENWLQYFPLSQILFVSGERLI 361

Query: 774 TDPATVMDEVQKFLGVLPHYNYSEALTFDSHKGFWCQLLEEGKT--KCLGKSKGRKYPPM 831
            DPA  M +VQ FLG L      +   F+  KGF C    E  +  +CLGKSKGR +P +
Sbjct: 362 VDPAGEMAKVQDFLG-LKRVVTEKHFYFNKTKGFPCLKKPEDSSAPRCLGKSKGRTHPRI 420

Query: 832 DSDSRTFLSSYYRDHNV 848
           D D    L  +Y+  N+
Sbjct: 421 DPDVIHRLRKFYKPFNL 437


>gi|5174463 heparan sulfate D-glucosaminyl  3-O-sulfotransferase 2
           [Homo sapiens]
          Length = 367

 Score =  129 bits (325), Expect = 9e-30
 Identities = 85/258 (32%), Positives = 132/258 (51%), Gaps = 17/258 (6%)

Query: 594 RLPKFLVIGPQKTGTTALYLFLVMHPSILSNSPSPKTFEEVQFFNRNNYHRGIDWYMDFF 653
           RLP+ L++G +K GT A+  F+ +HP + +    P       FF+RN Y RG+DWY    
Sbjct: 113 RLPQALIVGVKKGGTRAVLEFIRVHPDVRALGTEP------HFFDRN-YGRGLDWYRSL- 164

Query: 654 PVPSNVTTDFLFEKSANYFHSEEAPKRAASLVPKAKIITILIDPSDRAYSWYQHQRSHED 713
            +P  + +    EK+ +YF ++EAP+R  ++    K+I ++ +P  RA S Y    S + 
Sbjct: 165 -MPRTLESQITLEKTPSYFVTQEAPRRIFNMSRDTKLIVVVRNPVTRAISDYTQTLSKKP 223

Query: 714 PAALKFSFYEVISAGPRAPSELRALQKRCLVPGWYASHIERWLVYFPPFQLLIIDGQQLR 773
                   +E +S   R    L  +    +  G Y  H+E WL YFP  Q+  + G++L 
Sbjct: 224 DIPT----FEGLSFRNRTLG-LVDVSWNAIRIGMYVLHLESWLQYFPLAQIHFVSGERLI 278

Query: 774 TDPATVMDEVQKFLGVLPHYNYSEALTFDSHKGFWCQLLEEGK--TKCLGKSKGRKYPPM 831
           TDPA  M  VQ FLG+   +   +   F+  KGF C    E     +CLGKSKGR +  +
Sbjct: 279 TDPAGEMGRVQDFLGI-KRFITDKHFYFNKTKGFPCLKKTESSLLPRCLGKSKGRTHVQI 337

Query: 832 DSDSRTFLSSYYRDHNVE 849
           D +    L  +YR +N++
Sbjct: 338 DPEVIDQLREFYRPYNIK 355


>gi|45267824 heparan sulfate (glucosamine) 3-O-sulfotransferase 5
           [Homo sapiens]
          Length = 346

 Score =  128 bits (322), Expect = 2e-29
 Identities = 84/257 (32%), Positives = 130/257 (50%), Gaps = 16/257 (6%)

Query: 594 RLPKFLVIGPQKTGTTALYLFLVMHPSILSNSPSPKTFEEVQFF-NRNNYHRGIDWYMDF 652
           +LPK ++IG +K GT AL   L +HP+++      K  +E+ FF N  NY +GI+WY   
Sbjct: 89  QLPKAIIIGVRKGGTRALLEMLNLHPAVV------KASQEIHFFDNDENYGKGIEWYRKK 142

Query: 653 FPV--PSNVTTDFLFEKSANYFHSEEAPKRAASLVPKAKIITILIDPSDRAYSWYQHQRS 710
            P   P  +T     EKS  YF +EE P+R   +    K++ I+ +P+ RA S Y     
Sbjct: 143 MPFSYPQQIT----IEKSPAYFITEEVPERIYKMNSSIKLLIIVREPTTRAISDYTQVLE 198

Query: 711 HEDPAALKFSFYEVISAGPRAPSELRALQKRCLVPGWYASHIERWLVYFPPFQLLIIDGQ 770
            ++     +  +E ++  P    E+    K  +    Y  H+ERWL YFP  Q  ++DG 
Sbjct: 199 GKERKNKTYYKFEKLAIDPNT-CEVNTKYK-AVRTSIYTKHLERWLKYFPIEQFHVVDGD 256

Query: 771 QLRTDPATVMDEVQKFLGVLPHYNYSEALTFDSHKGFWCQLLEEGKTKCLGKSKGRKYPP 830
           +L T+P   +  V+KFL + P  +    L F++ +GF+C        KCL  SKGR +P 
Sbjct: 257 RLITEPLPELQLVEKFLNLPPRISQYN-LYFNATRGFYCLRFNIIFNKCLAGSKGRIHPE 315

Query: 831 MDSDSRTFLSSYYRDHN 847
           +D    T L  ++   N
Sbjct: 316 VDPSVITKLRKFFHPFN 332


>gi|5174467 heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3B1
           [Homo sapiens]
          Length = 390

 Score =  128 bits (321), Expect = 3e-29
 Identities = 86/263 (32%), Positives = 135/263 (51%), Gaps = 19/263 (7%)

Query: 594 RLPKFLVIGPQKTGTTALYLFLVMHPSILSNSPSPKTFEEVQFFNRNNYHRGIDWYMDFF 653
           +LP+ ++IG +K GT AL  FL +HP + +    P       FF+R+ Y +G+ WY D  
Sbjct: 136 QLPQAIIIGVKKGGTRALLEFLRVHPDVRAVGAEP------HFFDRS-YDKGLAWYRDL- 187

Query: 654 PVPSNVTTDFLFEKSANYFHSEEAPKRAASLVPKAKIITILIDPSDRAYSWYQHQRSHE- 712
            +P  +      EK+ +YF + EAP R +++    K+I ++ DP  RA S Y    S   
Sbjct: 188 -MPRTLDGQITMEKTPSYFVTREAPARISAMSKDTKLIVVVRDPVTRAISDYTQTLSKRP 246

Query: 713 DPAALKFSFYEVISAGPRAPSELRALQKRCLVPGWYASHIERWLVYFPPFQLLIIDGQQL 772
           D    +   ++  +AG      L       +  G YA H+E WL +FP  Q+L + G++L
Sbjct: 247 DIPTFESLTFKNRTAG------LIDTSWSAIQIGIYAKHLEHWLRHFPIRQMLFVSGERL 300

Query: 773 RTDPATVMDEVQKFLGVLPHYNYSEALTFDSHKGFWCQLLEEGKTK--CLGKSKGRKYPP 830
            +DPA  +  VQ FLG L      +   F+  KGF C    EG ++  CLGK+KGR +P 
Sbjct: 301 ISDPAGELGRVQDFLG-LKRIITDKHFYFNKTKGFPCLKKAEGSSRPHCLGKTKGRTHPE 359

Query: 831 MDSDSRTFLSSYYRDHNVELSKL 853
           +D +    L  +YR  N++  ++
Sbjct: 360 IDREVVRRLREFYRPFNLKFYQM 382


>gi|5174465 heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3A1
           [Homo sapiens]
          Length = 406

 Score =  128 bits (321), Expect = 3e-29
 Identities = 86/263 (32%), Positives = 135/263 (51%), Gaps = 19/263 (7%)

Query: 594 RLPKFLVIGPQKTGTTALYLFLVMHPSILSNSPSPKTFEEVQFFNRNNYHRGIDWYMDFF 653
           +LP+ ++IG +K GT AL  FL +HP + +    P       FF+R+ Y +G+ WY D  
Sbjct: 151 QLPQAIIIGVKKGGTRALLEFLRVHPDVRAVGAEP------HFFDRS-YDKGLAWYRDL- 202

Query: 654 PVPSNVTTDFLFEKSANYFHSEEAPKRAASLVPKAKIITILIDPSDRAYSWYQHQRSHE- 712
            +P  +      EK+ +YF + EAP R +++    K+I ++ DP  RA S Y    S   
Sbjct: 203 -MPRTLDGQITMEKTPSYFVTREAPARISAMSKDTKLIVVVRDPVTRAISDYTQTLSKRP 261

Query: 713 DPAALKFSFYEVISAGPRAPSELRALQKRCLVPGWYASHIERWLVYFPPFQLLIIDGQQL 772
           D    +   ++  +AG      L       +  G YA H+E WL +FP  Q+L + G++L
Sbjct: 262 DIPTFESLTFKNRTAG------LIDTSWSAIQIGIYAKHLEHWLRHFPIRQMLFVSGERL 315

Query: 773 RTDPATVMDEVQKFLGVLPHYNYSEALTFDSHKGFWCQLLEEGKTK--CLGKSKGRKYPP 830
            +DPA  +  VQ FLG L      +   F+  KGF C    EG ++  CLGK+KGR +P 
Sbjct: 316 ISDPAGELGRVQDFLG-LKRIITDKHFYFNKTKGFPCLKKAEGSSRPHCLGKTKGRTHPE 374

Query: 831 MDSDSRTFLSSYYRDHNVELSKL 853
           +D +    L  +YR  N++  ++
Sbjct: 375 IDREVVRRLREFYRPFNLKFYQM 397


>gi|4826764 heparan sulfate D-glucosaminyl 3-O-sulfotransferase 1
           precursor [Homo sapiens]
          Length = 307

 Score =  128 bits (321), Expect = 3e-29
 Identities = 85/280 (30%), Positives = 142/280 (50%), Gaps = 29/280 (10%)

Query: 583 RDIWSKEKTCDRLPKFLVIGPQKTGTTALYLFLVMHPSILSNSPSPKTFEEVQFFN-RNN 641
           RD  +   +  +LP+ ++IG +K GT AL   L +HP + +         EV FF+   +
Sbjct: 42  RDGVAPNGSAQQLPQTIIIGVRKGGTRALLEMLSLHPDVAAAE------NEVHFFDWEEH 95

Query: 642 YHRGIDWYMDFFPV--PSNVTTDFLFEKSANYFHSEEAPKRAASLVPKAKIITILIDPSD 699
           Y  G+ WY+   P   P  +T     EK+  YF S + P+R  S+ P  +++ IL DPS+
Sbjct: 96  YSHGLGWYLSQMPFSWPHQLTV----EKTPAYFTSPKVPERVYSMNPSIRLLLILRDPSE 151

Query: 700 RAYS-----WYQHQRSHEDPAALKFSFYEVISAGPRAPSELRALQKRCLVPGWYASHIER 754
           R  S     +Y H + H+   +++    E +    R   + +AL +       Y  H++ 
Sbjct: 152 RVLSDYTQVFYNHMQKHKPYPSIE----EFLVRDGRLNVDYKALNRSL-----YHVHMQN 202

Query: 755 WLVYFPPFQLLIIDGQQLRTDPATVMDEVQKFLGVLPHYNYSEALTFDSHKGFWCQLLEE 814
           WL +FP   + I+DG +L  DP   + +V++FL + P  N S    F+  KGF+C L + 
Sbjct: 203 WLRFFPLRHIHIVDGDRLIRDPFPEIQKVERFLKLSPQINASN-FYFNKTKGFYC-LRDS 260

Query: 815 GKTKCLGKSKGRKYPPMDSDSRTFLSSYYRDHNVELSKLL 854
           G+ +CL +SKGR +P +D      L  Y+ + N +  +L+
Sbjct: 261 GRDRCLHESKGRAHPQVDPKLLNKLHEYFHEPNKKFFELV 300


>gi|116089312 heparan sulfate (glucosamine) 3-O-sulfotransferase 6
           [Homo sapiens]
          Length = 311

 Score =  124 bits (311), Expect = 4e-28
 Identities = 83/258 (32%), Positives = 124/258 (48%), Gaps = 22/258 (8%)

Query: 594 RLPKFLVIGPQKTGTTALYLFLVMHPSILSNSPSPKTFEEVQFFNRNNYHRGIDWYMDFF 653
           R P+ L++G +K GT AL  FL +HP + +    P  F+         Y RG+ WY    
Sbjct: 58  RFPQALIVGVKKGGTRALLEFLRLHPDVRALGSEPHFFDRC-------YERGLAWYRSL- 109

Query: 654 PVPSNVTTDFLFEKSANYFHSEEAPKRAASLVPKAKIITILIDPSDRAYSWYQHQRSHED 713
            +P  +      EK+ +YF + EAP+R  ++ P  K+I ++ +P  RA S Y    S   
Sbjct: 110 -MPRTLDGQITMEKTPSYFVTREAPRRIHAMSPDTKLIVVVRNPVTRAISDYAQTLSKTP 168

Query: 714 --PAALKFSFYEVISAGPRAPSELRALQKRCLVPGWYASHIERWLVYFPPFQLLIIDGQQ 771
             P+    +F   +     A S +R         G YA H++ WL YFP    L + G++
Sbjct: 169 GLPSFRALAFRHGLGPVDTAWSAVRI--------GLYAQHLDHWLRYFPLSHFLFVSGER 220

Query: 772 LRTDPATVMDEVQKFLGVLPHYNYSEALTFDSHKGFWCQLLEEG--KTKCLGKSKGRKYP 829
           L +DPA  +  VQ FLG L      +   F++ KGF C    +G  + +CLGKSKGR +P
Sbjct: 221 LVSDPAGEVGRVQDFLG-LKRVVTDKHFYFNATKGFPCLKKAQGGSRPRCLGKSKGRPHP 279

Query: 830 PMDSDSRTFLSSYYRDHN 847
            +       L  +YR  N
Sbjct: 280 RVPQALVRRLQEFYRPFN 297


>gi|45505173 B cell RAG associated protein [Homo sapiens]
          Length = 561

 Score = 47.0 bits (110), Expect = 8e-05
 Identities = 73/311 (23%), Positives = 115/311 (36%), Gaps = 63/311 (20%)

Query: 595 LPKFLVIGPQKTGTTALYLFLVMHPSI-LSNSPSP-----KTFEEVQFFNRNNYHRGIDW 648
           LP F +IG  K GTT LY  L +HP +  S    P     K F  V+  +       ++ 
Sbjct: 253 LPHFYIIGQPKCGTTDLYDRLRLHPEVKFSAIKEPHWWTRKRFGIVRLRDGLRDRYPVED 312

Query: 649 YMDFFPV----------------PSNVTTDFLFEKSAN---------YFHSEEAPKRAAS 683
           Y+D F +                 S + T  + E SA+         +F+          
Sbjct: 313 YLDLFDLAAHQIHQGLQASSAKEQSKMNTIIIGEASASTMWDNNAWTFFYDNSTDGEPPF 372

Query: 684 LV--------PKAKIITILIDPSDRAYSWYQHQRSHEDPA---------ALKFSFYEVIS 726
           L         P A++I +L DP +R YS Y +  S    A         AL+     ++ 
Sbjct: 373 LTQDFIHAFQPNARLIVMLRDPVERLYSDYLYFASSNKSADDFHEKVTEALQLFENCMLD 432

Query: 727 AGPRA---PSELRALQKRCLVPGWYASHIERWLVYFPPFQLLIIDGQQLRTDPATVMDEV 783
              RA    + L       L  G YA ++  WL  F   Q LI+  +   ++    M +V
Sbjct: 433 YSLRACVYNNTLNNAMPVRLQVGLYAVYLLDWLSVFDKQQFLILRLEDHASNVKYTMHKV 492

Query: 784 QKFLGVLPHYNYSEALTFDSHKGFWCQLLEEGKTKCLGKSKGRKYPPMDSDSRTFLSSYY 843
            +FL + P     EA            L+ +       + + R   PM   ++  L  +Y
Sbjct: 493 FQFLNLGPLSEKQEA------------LMTKSPASNARRPEDRNLGPMWPITQKILRDFY 540

Query: 844 RDHNVELSKLL 854
           R  N  L+++L
Sbjct: 541 RPFNARLAQVL 551


>gi|56847626 sulfotransferase family, cytosolic, 1C, member 3 [Homo
           sapiens]
          Length = 304

 Score = 34.3 bits (77), Expect = 0.52
 Identities = 45/216 (20%), Positives = 85/216 (39%), Gaps = 39/216 (18%)

Query: 583 RDIWSKEKTCDRLPKFLVIGPQ-KTGTTALYLFLVMHPSILSNSPSPKTFEEVQFFNRNN 641
           ++ W K       P  L++    K+GTT ++  L M    + N    +  +  Q  +R+ 
Sbjct: 33  KEWWEKVCNFQAKPDDLILATYPKSGTTWMHEILDM----ILNDGDVEKCKRAQTLDRHA 88

Query: 642 YHRGIDWYMDF-FPVPSNVTTDFLFEKSANYFHSEEAPKRAASLVPKA------KIITIL 694
           +       ++  FP       +F+ E S+        P     L+P +      KI+ + 
Sbjct: 89  F-------LELKFPHKEKPDLEFVLEMSSPQLIKTHLPSH---LIPPSIWKENCKIVYVA 138

Query: 695 IDPSDRAYSWYQHQRSHE---DPAALKFSFYEVISAGPRAPSELRALQKRCLVPGWYASH 751
            +P D   S+Y   R      DP  L+  FYE   +G              +V G +  H
Sbjct: 139 RNPKDCLVSYYHFHRMASFMPDPQNLE-EFYEKFMSGK-------------VVGGSWFDH 184

Query: 752 IERWLVYFPPFQLLIIDGQQLRTDPATVMDEVQKFL 787
           ++ W       ++L +  + ++ DP   ++++ KFL
Sbjct: 185 VKGWWAAKDMHRILYLFYEDIKKDPKREIEKILKFL 220


>gi|4557481 ATP-binding cassette, sub-family C (CFTR/MRP), member 2
           [Homo sapiens]
          Length = 1545

 Score = 32.3 bits (72), Expect = 2.0
 Identities = 27/85 (31%), Positives = 41/85 (48%), Gaps = 3/85 (3%)

Query: 292 LSGK-RLTLSLDRYILVDIDDIFVGKEGTRMNTNDVKALLDTQNLLRAQITNFTFNLGFS 350
           L GK RL ++   + L  +D+I V   GT +      ALL  +      +  F  + G  
Sbjct: 810 LKGKTRLLVTHSMHFLPQVDEIVVLGNGTIVEKGSYSALLAKKGEFAKNLKTFLRHTGPE 869

Query: 351 GK-FYHTGTEEEDEGDDCLLGSVDE 374
            +   H G+EEED+ D  L+ SV+E
Sbjct: 870 EEATVHDGSEEEDD-DYGLISSVEE 893


>gi|7657633 sulfotransferase family 4A, member 1 [Homo sapiens]
          Length = 284

 Score = 31.6 bits (70), Expect = 3.4
 Identities = 26/118 (22%), Positives = 52/118 (44%), Gaps = 11/118 (9%)

Query: 688 AKIITILIDPSDRAYSWYQHQRSHEDPAALKFSFYEVISAGPRAPSELRALQKRCLVPGW 747
           +K+I +  +P D   S+YQ  RS     + + +F E            R +  +     W
Sbjct: 126 SKVIYMARNPKDLVVSYYQFHRSLRT-MSYRGTFQEFCR---------RFMNDKLGYGSW 175

Query: 748 YASHIERWLVYFPPFQLLIIDGQQLRTDPATVMDEVQKFLGVLPHYNYSEALTFDSHK 805
           +  H++ +  +     +L +  + +  D  T+++++ +FLGV       EALT   H+
Sbjct: 176 F-EHVQEFWEHRMDSNVLFLKYEDMHRDLVTMVEQLARFLGVSCDKAQLEALTEHCHQ 232


>gi|33350932 cytoplasmic dynein 1 heavy chain 1 [Homo sapiens]
          Length = 4646

 Score = 31.6 bits (70), Expect = 3.4
 Identities = 23/95 (24%), Positives = 45/95 (47%), Gaps = 9/95 (9%)

Query: 85   ESQYSSLGQDIIMILESSRFQ-YHIEIAPGKGDLPVLIDKMKGKYILIIYENILKYINM- 142
            E+ Y+ LG+D+      +++Q   ++I   +G       K +   ++I Y  +   +N+ 
Sbjct: 1066 ENIYNRLGEDL------NKWQALLVQIRKARGTFDNAETKKEFGPVVIDYGKVQSKVNLK 1119

Query: 143  -DSWNRSLLDKYCVEYGVGVIGFHKTSEKSVQSFQ 176
             DSW++ +L K+    G  +  FH    KS Q  +
Sbjct: 1120 YDSWHKEVLSKFGQMLGSNMTEFHSQISKSRQELE 1154


>gi|190014581 leucine rich repeat containing 2 [Homo sapiens]
          Length = 371

 Score = 31.6 bits (70), Expect = 3.4
 Identities = 25/99 (25%), Positives = 45/99 (45%), Gaps = 16/99 (16%)

Query: 45  ETASEVDCG---DLQHLPYQLMEVKAMKLFDASRTDPTVLVFVESQYSSLGQDIIMILES 101
           E    +DC    +L  LP++L  +K +   D S           +++SS+    I +L  
Sbjct: 190 ENLERLDCSGNLELMELPFELSNLKQVTFVDISA----------NKFSSVP---ICVLRM 236

Query: 102 SRFQYHIEIAPGKGDLPVLIDKMKGKYILIIYENILKYI 140
           S  Q+    +    DLP  ID+++     ++Y+N L Y+
Sbjct: 237 SNLQWLDISSNNLTDLPQDIDRLEELQSFLLYKNKLTYL 275


>gi|27545328 leucine rich repeat containing 2 [Homo sapiens]
          Length = 371

 Score = 31.6 bits (70), Expect = 3.4
 Identities = 25/99 (25%), Positives = 45/99 (45%), Gaps = 16/99 (16%)

Query: 45  ETASEVDCG---DLQHLPYQLMEVKAMKLFDASRTDPTVLVFVESQYSSLGQDIIMILES 101
           E    +DC    +L  LP++L  +K +   D S           +++SS+    I +L  
Sbjct: 190 ENLERLDCSGNLELMELPFELSNLKQVTFVDISA----------NKFSSVP---ICVLRM 236

Query: 102 SRFQYHIEIAPGKGDLPVLIDKMKGKYILIIYENILKYI 140
           S  Q+    +    DLP  ID+++     ++Y+N L Y+
Sbjct: 237 SNLQWLDISSNNLTDLPQDIDRLEELQSFLLYKNKLTYL 275


>gi|45446740 ATP-binding cassette, sub-family A, member 2 isoform a
            [Homo sapiens]
          Length = 2436

 Score = 31.2 bits (69), Expect = 4.4
 Identities = 31/113 (27%), Positives = 50/113 (44%), Gaps = 24/113 (21%)

Query: 759  FPPFQ-LLIIDGQQLRTDPATVMDEVQKFLGVLPHYN-YSEALTFDSHKGFWCQLLEEGK 816
            FPP      I G  +RT+    MDE++K LG+ P +N   + LT + H  F+ +L     
Sbjct: 1042 FPPTSGSATIYGHDIRTE----MDEIRKNLGMCPQHNVLFDRLTVEEHLWFYSRL----- 1092

Query: 817  TKCLGKSKGRKYPPMDSDSRTFLSSYYRDHNVELSKLLHKLGQPLPSWLRQEL 869
                 KS  ++    + D            ++ELS   H L Q L   ++++L
Sbjct: 1093 -----KSMAQEEIRREMDKMI--------EDLELSNKRHSLVQTLSGGMKRKL 1132


>gi|47078218 ATP-binding cassette, sub-family A, member 2 isoform b
            [Homo sapiens]
          Length = 2466

 Score = 31.2 bits (69), Expect = 4.4
 Identities = 31/113 (27%), Positives = 50/113 (44%), Gaps = 24/113 (21%)

Query: 759  FPPFQ-LLIIDGQQLRTDPATVMDEVQKFLGVLPHYN-YSEALTFDSHKGFWCQLLEEGK 816
            FPP      I G  +RT+    MDE++K LG+ P +N   + LT + H  F+ +L     
Sbjct: 1072 FPPTSGSATIYGHDIRTE----MDEIRKNLGMCPQHNVLFDRLTVEEHLWFYSRL----- 1122

Query: 817  TKCLGKSKGRKYPPMDSDSRTFLSSYYRDHNVELSKLLHKLGQPLPSWLRQEL 869
                 KS  ++    + D            ++ELS   H L Q L   ++++L
Sbjct: 1123 -----KSMAQEEIRREMDKMI--------EDLELSNKRHSLVQTLSGGMKRKL 1162


>gi|116517224 coiled-coil domain containing 144B [Homo sapiens]
          Length = 725

 Score = 31.2 bits (69), Expect = 4.4
 Identities = 37/163 (22%), Positives = 53/163 (32%), Gaps = 23/163 (14%)

Query: 562 FELFPDQKDPLWQNPCDDKRHRDIWSKEKTCDRLPKFLVIGPQKTGTTALYLFLVMHPSI 621
           FE FP+QK+P  +N      H    S+E  C    K                 L +H + 
Sbjct: 358 FETFPEQKEPSLKNIIHPYYHPYSGSQEHVCQSSSK-----------------LHLHENK 400

Query: 622 LSNSPSPKTFEEVQFFNRNNYHRGIDWYMDFFP------VPSNVTTDFLFEKSANYFHSE 675
           L      K      F   NN+H          P      +  +   D    K+ N     
Sbjct: 401 LDCDNDNKLGIGHIFSTDNNFHNDASTKKARNPEVVTVEMKEDQEFDLQMTKNMNQNSDS 460

Query: 676 EAPKRAASLVPKAKIITILIDPSDRAYSWYQHQRSHEDPAALK 718
            +     SL PK + ++ L   SDR    Y H+   +D    K
Sbjct: 461 GSTNNYKSLKPKLENLSSLPPDSDRTSEVYLHEELQQDMQKFK 503


>gi|62868225 aryl sulfotransferase [Homo sapiens]
          Length = 295

 Score = 30.8 bits (68), Expect = 5.7
 Identities = 23/105 (21%), Positives = 43/105 (40%), Gaps = 17/105 (16%)

Query: 687 KAKIITILIDPSDRAYSWYQHQR---SHEDPAALKFSFYEVISAGPRAPSELRALQKRCL 743
           K K++ +  +P D A S+Y   R   +H +P     SF E   AG               
Sbjct: 122 KVKVVYVARNPKDVAVSYYHFHRMEKAHPEPGTWD-SFLEKFMAG------------EVS 168

Query: 744 VPGWYASHIERWLVYFPPFQLLIIDGQQLRTDPATVMDEVQKFLG 788
              WY  H++ W        +L +  + ++ +P   + ++ +F+G
Sbjct: 169 YGSWY-QHVQEWWELSRTHPVLYLFYEDMKENPKREIQKILEFVG 212


>gi|62868223 aryl sulfotransferase [Homo sapiens]
          Length = 295

 Score = 30.8 bits (68), Expect = 5.7
 Identities = 23/105 (21%), Positives = 43/105 (40%), Gaps = 17/105 (16%)

Query: 687 KAKIITILIDPSDRAYSWYQHQR---SHEDPAALKFSFYEVISAGPRAPSELRALQKRCL 743
           K K++ +  +P D A S+Y   R   +H +P     SF E   AG               
Sbjct: 122 KVKVVYVARNPKDVAVSYYHFHRMEKAHPEPGTWD-SFLEKFMAG------------EVS 168

Query: 744 VPGWYASHIERWLVYFPPFQLLIIDGQQLRTDPATVMDEVQKFLG 788
              WY  H++ W        +L +  + ++ +P   + ++ +F+G
Sbjct: 169 YGSWY-QHVQEWWELSRTHPVLYLFYEDMKENPKREIQKILEFVG 212


>gi|29550921 sulfotransferase family, cytosolic, 1A,
           phenol-preferring, member 3 [Homo sapiens]
          Length = 295

 Score = 30.8 bits (68), Expect = 5.7
 Identities = 23/105 (21%), Positives = 43/105 (40%), Gaps = 17/105 (16%)

Query: 687 KAKIITILIDPSDRAYSWYQHQR---SHEDPAALKFSFYEVISAGPRAPSELRALQKRCL 743
           K K++ +  +P D A S+Y   R   +H +P     SF E   AG               
Sbjct: 122 KVKVVYVARNPKDVAVSYYHFHRMEKAHPEPGTWD-SFLEKFMAG------------EVS 168

Query: 744 VPGWYASHIERWLVYFPPFQLLIIDGQQLRTDPATVMDEVQKFLG 788
              WY  H++ W        +L +  + ++ +P   + ++ +F+G
Sbjct: 169 YGSWY-QHVQEWWELSRTHPVLYLFYEDMKENPKREIQKILEFVG 212


>gi|10835035 sulfotransferase family, cytosolic, 1A,
           phenol-preferring, member 3 [Homo sapiens]
          Length = 295

 Score = 30.8 bits (68), Expect = 5.7
 Identities = 23/105 (21%), Positives = 43/105 (40%), Gaps = 17/105 (16%)

Query: 687 KAKIITILIDPSDRAYSWYQHQR---SHEDPAALKFSFYEVISAGPRAPSELRALQKRCL 743
           K K++ +  +P D A S+Y   R   +H +P     SF E   AG               
Sbjct: 122 KVKVVYVARNPKDVAVSYYHFHRMEKAHPEPGTWD-SFLEKFMAG------------EVS 168

Query: 744 VPGWYASHIERWLVYFPPFQLLIIDGQQLRTDPATVMDEVQKFLG 788
              WY  H++ W        +L +  + ++ +P   + ++ +F+G
Sbjct: 169 YGSWY-QHVQEWWELSRTHPVLYLFYEDMKENPKREIQKILEFVG 212


>gi|197333706 leucine rich repeat containing 8 family, member D
           [Homo sapiens]
          Length = 858

 Score = 30.4 bits (67), Expect = 7.5
 Identities = 13/42 (30%), Positives = 21/42 (50%)

Query: 631 FEEVQFFNRNNYHRGIDWYMDFFPVPSNVTTDFLFEKSANYF 672
           F++  F N+  YH  + WY  +FP  + + T  L   S  +F
Sbjct: 143 FQQYVFINQMCYHLALPWYSKYFPYLALIHTIILMVSSNFWF 184


>gi|34222199 leucine rich repeat containing 8 family, member D [Homo
           sapiens]
          Length = 858

 Score = 30.4 bits (67), Expect = 7.5
 Identities = 13/42 (30%), Positives = 21/42 (50%)

Query: 631 FEEVQFFNRNNYHRGIDWYMDFFPVPSNVTTDFLFEKSANYF 672
           F++  F N+  YH  + WY  +FP  + + T  L   S  +F
Sbjct: 143 FQQYVFINQMCYHLALPWYSKYFPYLALIHTIILMVSSNFWF 184


>gi|166999223 glutamate receptor, metabotropic 1 isoform beta
           precursor [Homo sapiens]
          Length = 906

 Score = 30.0 bits (66), Expect = 9.8
 Identities = 21/84 (25%), Positives = 30/84 (35%), Gaps = 14/84 (16%)

Query: 377 WFPHMWSH-----MQPHLFHN---------ESSLVEQMILNKKFALEHGIPTDMGYAVAP 422
           WFP  W H     +  HL  N           SL E  + + K          M + +  
Sbjct: 367 WFPEFWQHRFQCRLPGHLLENPNFKRICTGNESLEENYVQDSKMGFVINAIYAMAHGLQN 426

Query: 423 HHSGVYPVHVQLYEAWKKVWNIKI 446
            H  + P HV L +A K +   K+
Sbjct: 427 MHHALCPGHVGLCDAMKPIDGSKL 450


>gi|166999098 glutamate receptor, metabotropic 1 isoform alpha
           precursor [Homo sapiens]
          Length = 1194

 Score = 30.0 bits (66), Expect = 9.8
 Identities = 21/84 (25%), Positives = 30/84 (35%), Gaps = 14/84 (16%)

Query: 377 WFPHMWSH-----MQPHLFHN---------ESSLVEQMILNKKFALEHGIPTDMGYAVAP 422
           WFP  W H     +  HL  N           SL E  + + K          M + +  
Sbjct: 367 WFPEFWQHRFQCRLPGHLLENPNFKRICTGNESLEENYVQDSKMGFVINAIYAMAHGLQN 426

Query: 423 HHSGVYPVHVQLYEAWKKVWNIKI 446
            H  + P HV L +A K +   K+
Sbjct: 427 MHHALCPGHVGLCDAMKPIDGSKL 450


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.139    0.434 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 34,885,987
Number of Sequences: 37866
Number of extensions: 1615768
Number of successful extensions: 3198
Number of sequences better than 10.0: 29
Number of HSP's better than 10.0 without gapping: 14
Number of HSP's successfully gapped in prelim test: 15
Number of HSP's that attempted gapping in prelim test: 3132
Number of HSP's gapped (non-prelim): 40
length of query: 873
length of database: 18,247,518
effective HSP length: 111
effective length of query: 762
effective length of database: 14,044,392
effective search space: 10701826704
effective search space used: 10701826704
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.