Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 4758648
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4758648 kinesin family member 5B [Homo sapiens]
(963 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4758648 kinesin family member 5B [Homo sapiens] 1876 0.0
gi|4758650 kinesin family member 5C [Homo sapiens] 1409 0.0
gi|45446749 kinesin family member 5A [Homo sapiens] 1332 0.0
gi|71061468 centromere protein E [Homo sapiens] 294 3e-79
gi|116686122 kinesin family member 4 [Homo sapiens] 290 4e-78
gi|46852174 kinesin family member 3A [Homo sapiens] 290 6e-78
gi|4758646 kinesin family member 3B [Homo sapiens] 282 9e-76
gi|150010604 kinesin family member 4B [Homo sapiens] 280 5e-75
gi|38569484 kinesin family member 21A [Homo sapiens] 273 6e-73
gi|30794488 kinesin family member 27 [Homo sapiens] 269 8e-72
gi|13699824 kinesin family member 11 [Homo sapiens] 267 3e-71
gi|83716024 kinesin family member 21B [Homo sapiens] 266 7e-71
gi|9910266 kinesin family member 15 [Homo sapiens] 262 1e-69
gi|41393559 kinesin family member 1B isoform alpha [Homo sapiens] 254 4e-67
gi|41393563 kinesin family member 1B isoform b [Homo sapiens] 254 4e-67
gi|170784809 kinesin family member 17 isoform b [Homo sapiens] 253 6e-67
gi|170784807 kinesin family member 17 isoform a [Homo sapiens] 253 6e-67
gi|19924175 axonal transport of synaptic vesicles [Homo sapiens] 249 9e-66
gi|41327691 kinesin-like motor protein C20orf23 [Homo sapiens] 247 3e-65
gi|203096856 kinesin family member 7 [Homo sapiens] 243 6e-64
gi|41352705 kinesin family member 3C [Homo sapiens] 241 2e-63
gi|157738629 kinesin family member 13A isoform d [Homo sapiens] 237 3e-62
gi|157738627 kinesin family member 13A isoform c [Homo sapiens] 237 3e-62
gi|157738625 kinesin family member 13A isoform b [Homo sapiens] 237 3e-62
gi|157738621 kinesin family member 13A isoform a [Homo sapiens] 237 3e-62
gi|40254834 kinesin family member 1C [Homo sapiens] 236 8e-62
gi|46852172 kinesin family member 13B [Homo sapiens] 226 6e-59
gi|194294510 kinesin family member C3 isoform 2 [Homo sapiens] 222 1e-57
gi|194294508 kinesin family member C3 isoform 3 [Homo sapiens] 222 1e-57
gi|94536858 kinesin family member C3 isoform 1 [Homo sapiens] 222 1e-57
>gi|4758648 kinesin family member 5B [Homo sapiens]
Length = 963
Score = 1876 bits (4860), Expect = 0.0
Identities = 963/963 (100%), Positives = 963/963 (100%)
Query: 1 MADLAECNIKVMCRFRPLNESEVNRGDKYIAKFQGEDTVVIASKPYAFDRVFQSSTSQEQ 60
MADLAECNIKVMCRFRPLNESEVNRGDKYIAKFQGEDTVVIASKPYAFDRVFQSSTSQEQ
Sbjct: 1 MADLAECNIKVMCRFRPLNESEVNRGDKYIAKFQGEDTVVIASKPYAFDRVFQSSTSQEQ 60
Query: 61 VYNDCAKKIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPEGMGIIPRIVQDIFNYIY 120
VYNDCAKKIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPEGMGIIPRIVQDIFNYIY
Sbjct: 61 VYNDCAKKIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPEGMGIIPRIVQDIFNYIY 120
Query: 121 SMDENLEFHIKVSYFEIYLDKIRDLLDVSKTNLSVHEDKNRVPYVKGCTERFVCSPDEVM 180
SMDENLEFHIKVSYFEIYLDKIRDLLDVSKTNLSVHEDKNRVPYVKGCTERFVCSPDEVM
Sbjct: 121 SMDENLEFHIKVSYFEIYLDKIRDLLDVSKTNLSVHEDKNRVPYVKGCTERFVCSPDEVM 180
Query: 181 DTIDEGKSNRHVAVTNMNEHSSRSHSIFLINVKQENTQTEQKLSGKLYLVDLAGSEKVSK 240
DTIDEGKSNRHVAVTNMNEHSSRSHSIFLINVKQENTQTEQKLSGKLYLVDLAGSEKVSK
Sbjct: 181 DTIDEGKSNRHVAVTNMNEHSSRSHSIFLINVKQENTQTEQKLSGKLYLVDLAGSEKVSK 240
Query: 241 TGAEGAVLDEAKNINKSLSALGNVISALAEGSTYVPYRDSKMTRILQDSLGGNCRTTIVI 300
TGAEGAVLDEAKNINKSLSALGNVISALAEGSTYVPYRDSKMTRILQDSLGGNCRTTIVI
Sbjct: 241 TGAEGAVLDEAKNINKSLSALGNVISALAEGSTYVPYRDSKMTRILQDSLGGNCRTTIVI 300
Query: 301 CCSPSSYNESETKSTLLFGQRAKTIKNTVCVNVELTAEQWKKKYEKEKEKNKILRNTIQW 360
CCSPSSYNESETKSTLLFGQRAKTIKNTVCVNVELTAEQWKKKYEKEKEKNKILRNTIQW
Sbjct: 301 CCSPSSYNESETKSTLLFGQRAKTIKNTVCVNVELTAEQWKKKYEKEKEKNKILRNTIQW 360
Query: 361 LENELNRWRNGETVPIDEQFDKEKANLEAFTVDKDITLTNDKPATAIGVIGNFTDAERRK 420
LENELNRWRNGETVPIDEQFDKEKANLEAFTVDKDITLTNDKPATAIGVIGNFTDAERRK
Sbjct: 361 LENELNRWRNGETVPIDEQFDKEKANLEAFTVDKDITLTNDKPATAIGVIGNFTDAERRK 420
Query: 421 CEEEIAKLYKQLDDKDEEINQQSQLVEKLKTQMLDQEELLASTRRDQDNMQAELNRLQAE 480
CEEEIAKLYKQLDDKDEEINQQSQLVEKLKTQMLDQEELLASTRRDQDNMQAELNRLQAE
Sbjct: 421 CEEEIAKLYKQLDDKDEEINQQSQLVEKLKTQMLDQEELLASTRRDQDNMQAELNRLQAE 480
Query: 481 NDASKEEVKEVLQALEELAVNYDQKSQEVEDKTKEYELLSDELNQKSATLASIDAELQKL 540
NDASKEEVKEVLQALEELAVNYDQKSQEVEDKTKEYELLSDELNQKSATLASIDAELQKL
Sbjct: 481 NDASKEEVKEVLQALEELAVNYDQKSQEVEDKTKEYELLSDELNQKSATLASIDAELQKL 540
Query: 541 KEMTNHQKKRAAEMMASLLKDLAEIGIAVGNNDVKQPEGTGMIDEEFTVARLYISKMKSE 600
KEMTNHQKKRAAEMMASLLKDLAEIGIAVGNNDVKQPEGTGMIDEEFTVARLYISKMKSE
Sbjct: 541 KEMTNHQKKRAAEMMASLLKDLAEIGIAVGNNDVKQPEGTGMIDEEFTVARLYISKMKSE 600
Query: 601 VKTMVKRCKQLESTQTESNKKMEENEKELAACQLRISQHEAKIKSLTEYLQNVEQKKRQL 660
VKTMVKRCKQLESTQTESNKKMEENEKELAACQLRISQHEAKIKSLTEYLQNVEQKKRQL
Sbjct: 601 VKTMVKRCKQLESTQTESNKKMEENEKELAACQLRISQHEAKIKSLTEYLQNVEQKKRQL 660
Query: 661 EESVDALSEELVQLRAQEKVHEMEKEHLNKVQTANEVKQAVEQQIQSHRETHQKQISSLR 720
EESVDALSEELVQLRAQEKVHEMEKEHLNKVQTANEVKQAVEQQIQSHRETHQKQISSLR
Sbjct: 661 EESVDALSEELVQLRAQEKVHEMEKEHLNKVQTANEVKQAVEQQIQSHRETHQKQISSLR 720
Query: 721 DEVEAKAKLITDLQDQNQKMMLEQERLRVEHEKLKATDQEKSRKLHELTVMQDRREQARQ 780
DEVEAKAKLITDLQDQNQKMMLEQERLRVEHEKLKATDQEKSRKLHELTVMQDRREQARQ
Sbjct: 721 DEVEAKAKLITDLQDQNQKMMLEQERLRVEHEKLKATDQEKSRKLHELTVMQDRREQARQ 780
Query: 781 DLKGLEETVAKELQTLHNLRKLFVQDLATRVKKSAEIDSDDTGGSAAQKQKISFLENNLE 840
DLKGLEETVAKELQTLHNLRKLFVQDLATRVKKSAEIDSDDTGGSAAQKQKISFLENNLE
Sbjct: 781 DLKGLEETVAKELQTLHNLRKLFVQDLATRVKKSAEIDSDDTGGSAAQKQKISFLENNLE 840
Query: 841 QLTKVHKQLVRDNADLRCELPKLEKRLRATAERVKALESALKEAKENASRDRKRYQQEVD 900
QLTKVHKQLVRDNADLRCELPKLEKRLRATAERVKALESALKEAKENASRDRKRYQQEVD
Sbjct: 841 QLTKVHKQLVRDNADLRCELPKLEKRLRATAERVKALESALKEAKENASRDRKRYQQEVD 900
Query: 901 RIKEAVRSKNMARRGHSAQIAKPIRPGQHPAASPTHPSAIRGGGAFVQNSQPVAVRGGGG 960
RIKEAVRSKNMARRGHSAQIAKPIRPGQHPAASPTHPSAIRGGGAFVQNSQPVAVRGGGG
Sbjct: 901 RIKEAVRSKNMARRGHSAQIAKPIRPGQHPAASPTHPSAIRGGGAFVQNSQPVAVRGGGG 960
Query: 961 KQV 963
KQV
Sbjct: 961 KQV 963
>gi|4758650 kinesin family member 5C [Homo sapiens]
Length = 957
Score = 1409 bits (3648), Expect = 0.0
Identities = 727/959 (75%), Positives = 829/959 (86%), Gaps = 16/959 (1%)
Query: 1 MADLAECNIKVMCRFRPLNESEVNRGDKYIAKFQGEDTVVIAS-KPYAFDRVFQSSTSQE 59
MAD AEC+IKVMCRFRPLNE+E+ RGDK+I KF+G++TVVI KPY FDRV +T+QE
Sbjct: 1 MADPAECSIKVMCRFRPLNEAEILRGDKFIPKFKGDETVVIGQGKPYVFDRVLPPNTTQE 60
Query: 60 QVYNDCAKKIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPEGMGIIPRIVQDIFNYI 119
QVYN CAK+IVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDP+ MGIIPRI DIF++I
Sbjct: 61 QVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPRIAHDIFDHI 120
Query: 120 YSMDENLEFHIKVSYFEIYLDKIRDLLDVSKTNLSVHEDKNRVPYVKGCTERFVCSPDEV 179
YSMDENLEFHIKVSYFEIYLDKIRDLLDVSKTNL+VHEDKNRVPYVKGCTERFV SP+EV
Sbjct: 121 YSMDENLEFHIKVSYFEIYLDKIRDLLDVSKTNLAVHEDKNRVPYVKGCTERFVSSPEEV 180
Query: 180 MDTIDEGKSNRHVAVTNMNEHSSRSHSIFLINVKQENTQTEQKLSGKLYLVDLAGSEKVS 239
MD IDEGK+NRHVAVTNMNEHSSRSHSIFLIN+KQEN +TE+KLSGKLYLVDLAGSEKVS
Sbjct: 181 MDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQENVETEKKLSGKLYLVDLAGSEKVS 240
Query: 240 KTGAEGAVLDEAKNINKSLSALGNVISALAEGS-TYVPYRDSKMTRILQDSLGGNCRTTI 298
KTGAEGAVLDEAKNINKSLSALGNVISALAEG+ T+VPYRDSKMTRILQDSLGGNCRTTI
Sbjct: 241 KTGAEGAVLDEAKNINKSLSALGNVISALAEGTKTHVPYRDSKMTRILQDSLGGNCRTTI 300
Query: 299 VICCSPSSYNESETKSTLLFGQRAKTIKNTVCVNVELTAEQWKKKYEKEKEKNKILRNTI 358
VICCSPS +NE+ETKSTL+FGQRAKTIKNTV VN+ELTAE+WKKKYEKEKEKNK L+N I
Sbjct: 301 VICCSPSVFNEAETKSTLMFGQRAKTIKNTVSVNLELTAEEWKKKYEKEKEKNKTLKNVI 360
Query: 359 QWLENELNRWRNGETVPIDEQFD-KEKANLEAFTVDKDITLTNDKPATAIGVIGNFTDAE 417
Q LE ELNRWRNGE VP DEQ K++ NLE D + N P V+ + E
Sbjct: 361 QHLEMELNRWRNGEAVPEDEQISAKDQKNLE--PCDNTPIIDNIAP-----VVAGISTEE 413
Query: 418 RRKCEEEIAKLYKQLDDKDEEINQQSQLVEKLKTQMLDQEELLASTRRDQDNMQAELNRL 477
+ K +EEI+ LY+QLDDKD+EINQQSQL EKLK QMLDQ+ELLASTRRD + +Q EL RL
Sbjct: 414 KEKYDEEISSLYRQLDDKDDEINQQSQLAEKLKQQMLDQDELLASTRRDYEKIQEELTRL 473
Query: 478 QAENDASKEEVKEVLQALEELAVNYDQKSQEVEDKTKEYELLSDELNQKSATLASIDAEL 537
Q EN+A+K+EVKEVLQALEELAVNYDQKSQEVEDKT+ E L+DEL QK+ TL + EL
Sbjct: 474 QIENEAAKDEVKEVLQALEELAVNYDQKSQEVEDKTRANEQLTDELAQKTTTLTTTQREL 533
Query: 538 QKLKEMTNHQKKRAAEMMASLLKDLAEIGIAVGNNDVKQ-PEGTGMIDEEFTVARLYISK 596
+L+E++NHQKKRA E++ LLKDL EIG +G NDVK + G+I+EEFT+ARLYISK
Sbjct: 534 SQLQELSNHQKKRATEILNLLLKDLGEIGGIIGTNDVKTLADVNGVIEEEFTMARLYISK 593
Query: 597 MKSEVKTMVKRCKQLESTQTESNKKMEENEKELAACQLRISQHEAKIKSLTEYLQNVEQK 656
MKSEVK++V R KQLES Q +SN+KM +E+ELAACQL ISQHEAKIKSLT+Y+QN+EQK
Sbjct: 594 MKSEVKSLVNRSKQLESAQMDSNRKMNASERELAACQLLISQHEAKIKSLTDYMQNMEQK 653
Query: 657 KRQLEESVDALSEELVQLRAQEKVHEM-----EKEHLNKVQTANEVKQAVEQQIQSHRET 711
+RQLEES D+LSEEL +LRAQEK+HE+ EKEHL ++Q A E+K+A+EQQ++SHRE
Sbjct: 654 RRQLEESQDSLSEELAKLRAQEKMHEVSFQDKEKEHLTRLQDAEEMKKALEQQMESHREA 713
Query: 712 HQKQISSLRDEVEAKAKLITDLQDQNQKMMLEQERLRVEHEKLKATDQEKSRKLHELTVM 771
HQKQ+S LRDE+E K K+I +++D NQK+ LEQE+L ++ KLK DQE+ KL +L ++
Sbjct: 714 HQKQLSRLRDEIEEKQKIIDEIRDLNQKLQLEQEKLSSDYNKLKIEDQEREMKLEKLLLL 773
Query: 772 QDRREQARQDLKGLEETVAKELQTLHNLRKLFVQDLATRVKKSAEIDSDDTGGSAAQKQK 831
D+REQAR+DLKGLEETV++ELQTLHNLRKLFVQDL TRVKKS E+D+DD GGSAAQKQK
Sbjct: 774 NDKREQAREDLKGLEETVSRELQTLHNLRKLFVQDLTTRVKKSVELDNDDGGGSAAQKQK 833
Query: 832 ISFLENNLEQLTKVHKQLVRDNADLRCELPKLEKRLRATAERVKALESALKEAKENASRD 891
ISFLENNLEQLTKVHKQLVRDNADLRCELPKLEKRLRATAERVKALESALKEAKENA RD
Sbjct: 834 ISFLENNLEQLTKVHKQLVRDNADLRCELPKLEKRLRATAERVKALESALKEAKENAMRD 893
Query: 892 RKRYQQEVDRIKEAVRSKNMARRGHSAQIAKPIRPGQHPAASPTHPSAIRGGGAFVQNS 950
RKRYQQEVDRIKEAVR+KNMARR HSAQIAKPIRPG +PA+SPT AIRGGG NS
Sbjct: 894 RKRYQQEVDRIKEAVRAKNMARRAHSAQIAKPIRPGHYPASSPTAVHAIRGGGGSSSNS 952
>gi|45446749 kinesin family member 5A [Homo sapiens]
Length = 1032
Score = 1332 bits (3446), Expect = 0.0
Identities = 677/939 (72%), Positives = 806/939 (85%), Gaps = 9/939 (0%)
Query: 6 ECNIKVMCRFRPLNESEVNRGDKYIAKFQGEDTVVIASKPYAFDRVFQSSTSQEQVYNDC 65
EC+IKV+CRFRPLN++E+ RGDK+I FQG+D+VVI KPY FDRVF +T+QEQVY+ C
Sbjct: 7 ECSIKVLCRFRPLNQAEILRGDKFIPIFQGDDSVVIGGKPYVFDRVFPPNTTQEQVYHAC 66
Query: 66 AKKIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPEGMGIIPRIVQDIFNYIYSMDEN 125
A +IVKDVL GYNGTIFAYGQTSSGKTHTMEGKLHDP+ MGIIPRI +DIFN+IYSMDEN
Sbjct: 67 AMQIVKDVLAGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPRIARDIFNHIYSMDEN 126
Query: 126 LEFHIKVSYFEIYLDKIRDLLDVSKTNLSVHEDKNRVPYVKGCTERFVCSPDEVMDTIDE 185
LEFHIKVSYFEIYLDKIRDLLDV+KTNLSVHEDKNRVP+VKGCTERFV SP+E++D IDE
Sbjct: 127 LEFHIKVSYFEIYLDKIRDLLDVTKTNLSVHEDKNRVPFVKGCTERFVSSPEEILDVIDE 186
Query: 186 GKSNRHVAVTNMNEHSSRSHSIFLINVKQENTQTEQKLSGKLYLVDLAGSEKVSKTGAEG 245
GKSNRHVAVTNMNEHSSRSHSIFLIN+KQEN +TEQKLSGKLYLVDLAGSEKVSKTGAEG
Sbjct: 187 GKSNRHVAVTNMNEHSSRSHSIFLINIKQENMETEQKLSGKLYLVDLAGSEKVSKTGAEG 246
Query: 246 AVLDEAKNINKSLSALGNVISALAEGS-TYVPYRDSKMTRILQDSLGGNCRTTIVICCSP 304
AVLDEAKNINKSLSALGNVISALAEG+ +YVPYRDSKMTRILQDSLGGNCRTT+ ICCSP
Sbjct: 247 AVLDEAKNINKSLSALGNVISALAEGTKSYVPYRDSKMTRILQDSLGGNCRTTMFICCSP 306
Query: 305 SSYNESETKSTLLFGQRAKTIKNTVCVNVELTAEQWKKKYEKEKEKNKILRNTIQWLENE 364
SSYN++ETKSTL+FGQRAKTIKNT VN+ELTAEQWKKKYEKEKEK K + TI LE E
Sbjct: 307 SSYNDAETKSTLMFGQRAKTIKNTASVNLELTAEQWKKKYEKEKEKTKAQKETIAKLEAE 366
Query: 365 LNRWRNGETVPIDEQFDKEKANLEAFTVDKDITLTNDKPATAIGVIGNFTDAERRKCEEE 424
L+RWRNGE VP E+ E+A L A ++ T ND + ++ ER+K EEE
Sbjct: 367 LSRWRNGENVPETERLAGEEAALGAELCEE--TPVNDNSS----IVVRIAPEERQKYEEE 420
Query: 425 IAKLYKQLDDKDEEINQQSQLVEKLKTQMLDQEELLASTRRDQDNMQAELNRLQAENDAS 484
I +LYKQLDDKD+EINQQSQL+EKLK QMLDQEELL STR D + +Q EL+ LQ+ENDA+
Sbjct: 421 IRRLYKQLDDKDDEINQQSQLIEKLKQQMLDQEELLVSTRGDNEKVQRELSHLQSENDAA 480
Query: 485 KEEVKEVLQALEELAVNYDQKSQEVEDKTKEYELLSDELNQKSATLASIDAELQKLKEMT 544
K+EVKEVLQALEELAVNYDQKSQEVE+K+++ +LL DEL+QK AT+ S+++ELQ+L+E++
Sbjct: 481 KDEVKEVLQALEELAVNYDQKSQEVEEKSQQNQLLVDELSQKVATMLSLESELQRLQEVS 540
Query: 545 NHQKKRAAEMMASLLKDLAEIGIAVGNNDVKQP-EGTGMIDEEFTVARLYISKMKSEVKT 603
HQ+KR AE++ L+KDL+E + VGN ++K P E +G I+EEFTVARLYISK+KSEVK+
Sbjct: 541 GHQRKRIAEVLNGLMKDLSEFSVIVGNGEIKLPVEISGAIEEEFTVARLYISKIKSEVKS 600
Query: 604 MVKRCKQLESTQTESNKKMEENEKELAACQLRISQHEAKIKSLTEYLQNVEQKKRQLEES 663
+VKRC+QLE+ Q E ++KME +EL++CQL ISQHEAKI+SLTEY+Q+VE KKR LEES
Sbjct: 601 VVKRCRQLENLQVECHRKMEVTGRELSSCQLLISQHEAKIRSLTEYMQSVELKKRHLEES 660
Query: 664 VDALSEELVQLRAQEKVHEME-KEHLNKVQTANEVKQAVEQQIQSHRETHQKQISSLRDE 722
D+LS+EL +L+AQE VHE+ K+ Q A+EVK+A+E Q++SHRE H +Q++ LRDE
Sbjct: 661 YDSLSDELAKLQAQETVHEVALKDKEPDTQDADEVKKALELQMESHREAHHRQLARLRDE 720
Query: 723 VEAKAKLITDLQDQNQKMMLEQERLRVEHEKLKATDQEKSRKLHELTVMQDRREQARQDL 782
+ K K I +L+D NQK+ LE E+L+ ++EKLK+ + EKS KL ELT + +R EQ++QDL
Sbjct: 721 INEKQKTIDELKDLNQKLQLELEKLQADYEKLKSEEHEKSTKLQELTFLYERHEQSKQDL 780
Query: 783 KGLEETVAKELQTLHNLRKLFVQDLATRVKKSAEIDSDDTGGSAAQKQKISFLENNLEQL 842
KGLEETVA+ELQTLHNLRKLFVQD+ TRVKKSAE++ +D+GG +QKQKISFLENNLEQL
Sbjct: 781 KGLEETVARELQTLHNLRKLFVQDVTTRVKKSAEMEPEDSGGIHSQKQKISFLENNLEQL 840
Query: 843 TKVHKQLVRDNADLRCELPKLEKRLRATAERVKALESALKEAKENASRDRKRYQQEVDRI 902
TKVHKQLVRDNADLRCELPKLEKRLRATAERVKALE ALKEAKE A +D++RYQQEVDRI
Sbjct: 841 TKVHKQLVRDNADLRCELPKLEKRLRATAERVKALEGALKEAKEGAMKDKRRYQQEVDRI 900
Query: 903 KEAVRSKNMARRGHSAQIAKPIRPGQHPAASPTHPSAIR 941
KEAVR K+ +RGHSAQIAKP+RPG +PA+SPT+P R
Sbjct: 901 KEAVRYKSSGKRGHSAQIAKPVRPGHYPASSPTNPYGTR 939
>gi|71061468 centromere protein E [Homo sapiens]
Length = 2701
Score = 294 bits (752), Expect = 3e-79
Identities = 271/982 (27%), Positives = 457/982 (46%), Gaps = 120/982 (12%)
Query: 9 IKVMCRFRPLNESEVNRGDKYIAKFQGEDTVVI---ASKPYAFDRVFQSSTSQEQVYNDC 65
+ V R RPLN E + G+ ++ ++ V+ SK + FDRVF + + + VY +
Sbjct: 7 VAVCVRVRPLNSREESLGETAQVYWKTDNNVIYQVDGSKSFNFDRVFHGNETTKNVYEEI 66
Query: 66 AKKIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPEGMGIIPRIVQDIFNYIYSMDEN 125
A I+ ++GYNGTIFAYGQT+SGKT+TM G + +G+IPR + DIF I +
Sbjct: 67 AAPIIDSAIQGYNGTIFAYGQTASGKTYTMMG---SEDHLGVIPRAIHDIFQKIKKFPDR 123
Query: 126 LEFHIKVSYFEIYLDKIRDLL--DVSKTNLSVHEDKNRVPYVKGCTERFVCSPDEVMDTI 183
EF ++VSY EIY + I DLL L + ED NR YV TE V + + + I
Sbjct: 124 -EFLLRVSYMEIYNETITDLLCGTQKMKPLIIREDVNRNVYVADLTEEVVYTSEMALKWI 182
Query: 184 DEGKSNRHVAVTNMNEHSSRSHSIFLINVKQENTQTEQKLSGK-----LYLVDLAGSEKV 238
+G+ +RH T MN+ SSRSH+IF + ++ G L LVDLAGSE+
Sbjct: 183 TKGEKSRHYGETKMNQRSSRSHTIFRMILESREKGEPSNCEGSVKVSHLNLVDLAGSERA 242
Query: 239 SKTGAEGAVLDEAKNINKSLSALGNVISALAEGST--YVPYRDSKMTRILQDSLGGNCRT 296
++TGA G L E NIN+SL LG VI L++G ++ YRDSK+TRILQ+SLGGN +T
Sbjct: 243 AQTGAAGVRLKEGCNINRSLFILGQVIKKLSDGQVGGFINYRDSKLTRILQNSLGGNAKT 302
Query: 297 TIVICCSPSSYNESETKSTLLFGQRAKTIKNTVCVNVELTAEQWKKKYEKE--------- 347
I+ +P S++ ET + L F AK +KNT VN T E K+Y KE
Sbjct: 303 RIICTITPVSFD--ETLTALQFASTAKYMKNTPYVNEVSTDEALLKRYRKEIMDLKKQLE 360
Query: 348 --------------------KEKNKILRNTIQWLENELNRWRNGETVPIDEQFDKEKANL 387
+EK+ + + + +EN ++ + ++ ++
Sbjct: 361 EVSLETRAQAMEKDQLAQLLEEKDLLQKVQNEKIENLTRMLVTSSSLTLQQELKAKRKRR 420
Query: 388 EAFTVDKDITLTNDKPATAIGVIGNFTDAERRKCEEEIAKLYKQLDDK--------DEEI 439
+ + K + N A + N T K + L +++D+ +
Sbjct: 421 VTWCLGKINKMKNSNYADQFNIPTNIT----TKTHKLSINLLREIDESVCSESDVFSNTL 476
Query: 440 NQQSQLVEKLKTQMLDQEEL---LASTRRDQDNMQAELNRLQAENDASKEEVKE-----V 491
+ S++ T++L+QE + L S R D DN+ + +L+ E + + ++KE
Sbjct: 477 DTLSEIEWNPATKLLNQENIESELNSLRADYDNLVLDYEQLRTEKEEMELKLKEKNDLDE 536
Query: 492 LQALEELAVNYDQKSQEVEDKTKEYEL----------LSDELNQKSATLASIDAELQKLK 541
+ALE DQ+ Q + + + L L +EL+ K L + +++KL+
Sbjct: 537 FEALER-KTKKDQEMQLIHEISNLKNLVKHAEVYNQDLENELSSKVELLREKEDQIKKLQ 595
Query: 542 EMTNHQKKRAAEMMASLLKDLAEIGIAVGNNDVKQPEGTGMIDEEFTV--ARLYISKMKS 599
E + QK +M S + E D KQ + T + D E A+ + ++S
Sbjct: 596 EYIDSQKLENIKMDLSYSLESIE--------DPKQMKQT-LFDAETVALDAKRESAFLRS 646
Query: 600 EVKTMVKRCKQLESTQTESNKKMEENEKELAACQLRISQHEAKIK---SLTEYLQNVEQK 656
E + ++ K+L +T K+ME + QL SQ EAK K L + LQ+ +
Sbjct: 647 ENLELKEKMKELATTY----KQMEND------IQLYQSQLEAKKKMQVDLEKELQSAFNE 696
Query: 657 KRQLEESVDAL--SEELVQLRAQEKVHEMEKEHLNKVQTANEVKQAVEQQIQSHRETHQK 714
+L +D + L L + K+ +++KE LNK NE + E + S ++
Sbjct: 697 ITKLTSLIDGKVPKDLLCNLELEGKITDLQKE-LNKEVEENEALRE-EVILLSELKSLPS 754
Query: 715 QISSLRDEVEAKAKLITDLQDQNQKMMLEQERLRVEHEKLKATDQEKSRKLHELTVMQDR 774
++ LR E++ K++ + + + K+ E + +++ +E + +L Q
Sbjct: 755 EVERLRKEIQDKSEELHIITSEKDKLFSEVVH---KESRVQGLLEEIGKTKDDLATTQSN 811
Query: 775 ---REQARQDLKGLEETVAKELQTLHNLRKLFVQDLATRVKKSAEIDSDDTGGSAAQKQK 831
+Q Q+ K L ++ + + + Q++ K++ + DS A K +
Sbjct: 812 YKSTDQEFQNFKTLHMDFEQKYKMVLEENERMNQEIVNLSKEAQKFDS----SLGALKTE 867
Query: 832 ISFLENNLEQLTKVHKQLVRDNADLRCELPKLEKRLRATAERVKALESALKEAKENASRD 891
+S+ L++ T+ ++ + + L+ +L + L+ T ER K L + E + +
Sbjct: 868 LSYKTQELQEKTREVQERLNEMEQLKEQLENRDSTLQ-TVEREKTL---ITEKLQQTLEE 923
Query: 892 RKRYQQEVDRIKEAVRSKNMAR 913
K QE D +K+ S + R
Sbjct: 924 VKTLTQEKDDLKQLQESLQIER 945
Score = 96.3 bits (238), Expect = 1e-19
Identities = 135/625 (21%), Positives = 284/625 (45%), Gaps = 98/625 (15%)
Query: 333 VELTAEQWKKKYEKEKEKNKILRNTIQWLENELNRWRNGETVPIDEQFDKEKANLEAFTV 392
+E T Q K++ + K + TI +EL R + +T I D EK++ + +
Sbjct: 1226 IEATGLQTKEELKIAHIHLKEHQETI----DELRRSVSEKTAQIINTQDLEKSHTK---L 1278
Query: 393 DKDITLTNDKPATAIGVIGNFTD-AERRKCEEEIAKLYKQLDDKDEEINQQSQLVE-KLK 450
++I + +++ ++ N + +E ++ E+ L +Q KD + ++ +L
Sbjct: 1279 QEEIPVLHEEQE----LLPNVKEVSETQETMNELELLTEQSTTKDSTTLARIEMERLRLN 1334
Query: 451 TQMLDQEELLASTRRDQDNMQAELNRLQAENDASKEEVKEVL------QALEELAVNYDQ 504
+ + +E + S +++DN++ L+ ++D KE ++E L Q+ +E ++N +
Sbjct: 1335 EKFQESQEEIKSLTKERDNLKTIKEALEVKHDQLKEHIRETLAKIQESQSKQEQSLNMKE 1394
Query: 505 KSQEVEDKTKEYEL-----------------LSDELNQKSATLASIDAE---LQKLKEMT 544
K E E E LS L + + S+ E LQ+L+E+
Sbjct: 1395 KDNETTKIVSEMEQFKPKDSALLRIEIEMLGLSKRLQESHDEMKSVAKEKDDLQRLQEVL 1454
Query: 545 NHQ----KKRAAEMMASLLKDLAEIGIAVGNNDVKQPEGTGMIDEEFTVARLYISKMKSE 600
+ K+ E++A L+ E+ +A + +K+ E T I+E R+ +S+ ++E
Sbjct: 1455 QSESDQLKENIKEIVAKHLETEEELKVA--HCCLKEQEET--INE----LRVNLSEKETE 1506
Query: 601 VKTMVKRCKQLESTQTESNKKMEE-NEKELAACQLRISQHEAKIKSLTEYLQNVEQKKRQ 659
+ T+ K QLE+ + K++E EKE +IS+ + K+ L ++ ++ + K
Sbjct: 1507 ISTIQK---QLEAINDKLQNKIQEIYEKEEQFNIKQISEVQEKVNELKQFKEHRKAKDSA 1563
Query: 660 LEESVDALSEELVQLRAQEKVHEM-----EKEHLNKVQTA-----NEVKQAVEQQIQSHR 709
L +S+++ EL R QE E+ EKE + +VQ A +++K+ ++ + +
Sbjct: 1564 L-QSIESKMLELTN-RLQESQEEIQIMIKEKEEMKRVQEALQIERDQLKENTKEIVAKMK 1621
Query: 710 ETHQKQISSLR----DEVEAKAKLITDLQDQNQKMMLEQERLRVEHEKLKATDQEKSRKL 765
E+ +K+ L+ +E + K I L++Q + L E + E+ +L E ++
Sbjct: 1622 ESQEKEYQFLKMTAVNETQEKMCEIEHLKEQFETQKLNLENIETENIRLTQILHENLEEM 1681
Query: 766 HELTVMQDRREQARQDLKGLEETVAKELQTL-HNLRKLFVQDLATRVKKSAEIDSDDTGG 824
+T + R DL+ +EET+ E L NLR+ +DL
Sbjct: 1682 RSVT-------KERDDLRSVEETLKVERDQLKENLRETITRDL----------------- 1717
Query: 825 SAAQKQKISFLENNLEQLTKVHKQLVRDNADLRCELPKLEKRLRATAERVKALESALKEA 884
+++++ + +L++ + +L ++ E+ ++K L + + +KA + ++E
Sbjct: 1718 --EKQEELKIVHMHLKEHQETIDKLRGIVSEKTNEISNMQKDLEHSNDALKAQDLKIQEE 1775
Query: 885 KENASRDRKRYQQEVDRIKEAVRSK 909
A K Q+ +D+++ V K
Sbjct: 1776 LRIAHMHLKEQQETIDKLRGIVSEK 1800
Score = 90.5 bits (223), Expect = 7e-18
Identities = 154/802 (19%), Positives = 326/802 (40%), Gaps = 80/802 (9%)
Query: 151 TNLSVHEDKNRVPYVKGCTERFVCSPDEV----MDTIDEGKSNRHVAVTNMNEHSSRSHS 206
TN++ K + ++ E VCS +V +DT+ E + N + N S +S
Sbjct: 444 TNITTKTHKLSINLLREIDES-VCSESDVFSNTLDTLSEIEWNPATKLLNQENIESELNS 502
Query: 207 I------FLINVKQENTQTEQ---KLSGKLYLVDLAGSEKVSKTGAEGAVLDEAKNINKS 257
+ +++ +Q T+ E+ KL K L + E+ +K E ++ E N+ K+
Sbjct: 503 LRADYDNLVLDYEQLRTEKEEMELKLKEKNDLDEFEALERKTKKDQEMQLIHEISNL-KN 561
Query: 258 LSALGNVISALAEG--STYVPYRDSKMTRI--LQDSLGGNCRTTIVICCSPSSYNESETK 313
L V + E S+ V K +I LQ+ + I + S S + + K
Sbjct: 562 LVKHAEVYNQDLENELSSKVELLREKEDQIKKLQEYIDSQKLENIKMDLSYSLESIEDPK 621
Query: 314 STLLFGQRAKTI--KNTVCVNVELTAEQWKKKYEKEKEKNKILRNTIQWLENELNRWRNG 371
Q +T+ TV ++ + + + + + KEK K L T + +EN++ +++
Sbjct: 622 ------QMKQTLFDAETVALDAKRESAFLRSENLELKEKMKELATTYKQMENDIQLYQSQ 675
Query: 372 ETVPIDEQFDKEKANLEAFT-VDKDITLTNDKPATAIGVIGNFTDAERRKCEEEIAKLYK 430
Q D EK AF + K +L + K + C E L
Sbjct: 676 LEAKKKMQVDLEKELQSAFNEITKLTSLIDGKVPKDL------------LCNLE---LEG 720
Query: 431 QLDDKDEEINQQSQLVEKLKTQMLDQEELLASTRRDQDNMQAELNRLQAENDASKEEVKE 490
++ D +E+N++ + E L+ +++ EL ++ +E+ RL+ E EE+
Sbjct: 721 KITDLQKELNKEVEENEALREEVILLSEL--------KSLPSEVERLRKEIQDKSEELHI 772
Query: 491 VLQALEELAVNYDQKSQEVEDKTKEYELLSDELNQKSATLASIDAELQKLKEMTNHQKKR 550
+ ++L K V+ +E D+L + S D E Q K + +++
Sbjct: 773 ITSEKDKLFSEVVHKESRVQGLLEEIGKTKDDLATTQSNYKSTDQEFQNFKTLHMDFEQK 832
Query: 551 AAEMMASLLKDLAEIGIAVGNNDVKQPEGTGMIDEEFTVARLYISKMKSEVKTMVKRCKQ 610
++ + EI + + K G + E + + + EV+ + +Q
Sbjct: 833 YKMVLEENERMNQEI-VNLSKEAQKFDSSLGALKTELSYKTQELQEKTREVQERLNEMEQ 891
Query: 611 LESTQTESNKKMEENEKELAACQLRISQHEAKIKSLTEYLQNVEQKKRQLEESVDALSEE 670
L+ + ++ E+E ++ Q ++K+LT+ +++Q + L+ D L +
Sbjct: 892 LKEQLENRDSTLQTVEREKTLITEKLQQTLEEVKTLTQEKDDLKQLQESLQIERDQLKSD 951
Query: 671 L-----VQLRAQEKVHEMEKEHLNKVQTANEVKQAVEQQIQSHRETH-QKQISSLRDEVE 724
+ + + QE++ + +T N +K + +++ R H ++ +DE +
Sbjct: 952 IHDTVNMNIDTQEQLRNALESLKQHQETINTLKSKISEEVS--RNLHMEENTGETKDEFQ 1009
Query: 725 AKAKLITDLQDQNQKMM------LEQERLRVEHEKLKATDQEKSRKLHELTVMQDRREQA 778
K I QD K ++ + + K+ + QEK+ L + +EQ
Sbjct: 1010 QKMVGIDKKQDLEAKNTQTLTADVKDNEIIEQQRKIFSLIQEKNELQQMLESVIAEKEQL 1069
Query: 779 RQDLKGLEETVAKELQTLHNLRKLFVQDLATRVKKSAEIDSDDTGGSAAQKQKISFLENN 838
+ DLK E + ++ LR L +KK EI + + + ++ ++S +
Sbjct: 1070 KTDLK---ENIEMTIENQEELRL-----LGDELKKQQEIVAQEKNHAIKKEGELSRTCDR 1121
Query: 839 LEQLTKVHKQLVRDNADLRCELPKLEKRLRATAERVKALESALKEAK------ENASRDR 892
L ++ + K+ + + + +L +++ + +++ +E+ E K E+ +R
Sbjct: 1122 LAEVEEKLKEKSQQLQEKQQQLLNVQEEMSEMQKKINEIENLKNELKNKELTLEHMETER 1181
Query: 893 KRYQQEVDRIKEAVRSKNMARR 914
Q+++ E V+S R+
Sbjct: 1182 LELAQKLNENYEEVKSITKERK 1203
Score = 90.1 bits (222), Expect = 9e-18
Identities = 137/697 (19%), Positives = 288/697 (41%), Gaps = 140/697 (20%)
Query: 320 QRAKTIKNTVCVNVELTAEQWKKKYEKEKEKNKILRNTIQWLENELNRWRNGE--TVPID 377
Q I +TV +N++ T EQ + E K+ + + + E++R + E T
Sbjct: 947 QLKSDIHDTVNMNID-TQEQLRNALESLKQHQETINTLKSKISEEVSRNLHMEENTGETK 1005
Query: 378 EQFDKEKANLEAFTVDKDITLTNDKPATAIGVIGNFTDAERRKCEEEIAKLYKQLDDKDE 437
++F ++ ++ +D+ N + TA D KD
Sbjct: 1006 DEFQQKMVGIDK---KQDLEAKNTQTLTA--------------------------DVKDN 1036
Query: 438 EINQQSQLV---------------------EKLKTQMLD--------------------- 455
EI +Q + + E+LKT + +
Sbjct: 1037 EIIEQQRKIFSLIQEKNELQQMLESVIAEKEQLKTDLKENIEMTIENQEELRLLGDELKK 1096
Query: 456 QEELLASTRRDQDNMQAELNRL---QAENDASKEEVKEVLQALEELAVNYDQKSQEVEDK 512
Q+E++A + + EL+R AE + +E + LQ ++ +N ++ E++ K
Sbjct: 1097 QQEIVAQEKNHAIKKEGELSRTCDRLAEVEEKLKEKSQQLQEKQQQLLNVQEEMSEMQKK 1156
Query: 513 TKEYELLSDELNQKSATLASIDAE----LQKLKEMTNHQKKRAAEMMASLLKDLAEIGIA 568
E E L +EL K TL ++ E QKL E N+++ ++ +LK+L +
Sbjct: 1157 INEIENLKNELKNKELTLEHMETERLELAQKLNE--NYEEVKSITKERKVLKELQKSFET 1214
Query: 569 VGNN---DVKQPEGTGM-IDEEFTVARLYISKMKSEV----KTMVKRCKQLESTQ--TES 618
++ +++ E TG+ EE +A +++ + + + +++ ++ Q+ +TQ +S
Sbjct: 1215 ERDHLRGYIREIEATGLQTKEELKIAHIHLKEHQETIDELRRSVSEKTAQIINTQDLEKS 1274
Query: 619 NKKMEE-------------NEKELAACQLRISQHEAKIKSLT----EYLQNVEQKKRQLE 661
+ K++E N KE++ Q +++ E + T L +E ++ +L
Sbjct: 1275 HTKLQEEIPVLHEEQELLPNVKEVSETQETMNELELLTEQSTTKDSTTLARIEMERLRLN 1334
Query: 662 ESVDALSEELVQLRAQEKVHEMEKEHLNKVQTANEV-----KQAVEQQIQSHRETHQKQI 716
E EE+ L E+++L ++ A EV K+ + + + +E+ KQ
Sbjct: 1335 EKFQESQEEIKSL-------TKERDNLKTIKEALEVKHDQLKEHIRETLAKIQESQSKQE 1387
Query: 717 SSL--RDEVEAKAKLITDLQDQNQK----------MMLEQERLRVEHEKLKATDQEKSRK 764
SL +++ K++++++ K M+ +RL+ H+++K+ +EK
Sbjct: 1388 QSLNMKEKDNETTKIVSEMEQFKPKDSALLRIEIEMLGLSKRLQESHDEMKSVAKEKDDL 1447
Query: 765 LHELTVMQDRREQARQDLKGLEETVAKELQTLHNLRK---LFVQDLATRVKKSAEIDSDD 821
V+Q +Q ++++K E VAK L+T L+ + T + + +
Sbjct: 1448 QRLQEVLQSESDQLKENIK---EIVAKHLETEEELKVAHCCLKEQEETINELRVNLSEKE 1504
Query: 822 TGGSAAQKQKISFLENNLEQLTKVHKQLVRDNADLRCELPKLEKRLRATAERVKALESAL 881
T S QKQ + + ++ +++++ + N E+ + L+ E KA +SAL
Sbjct: 1505 TEISTIQKQLEAINDKLQNKIQEIYEKEEQFNIKQISEVQEKVNELKQFKEHRKAKDSAL 1564
Query: 882 KEAKENASRDRKRYQQEVDRIKEAVRSKNMARRGHSA 918
+ + R Q+ + I+ ++ K +R A
Sbjct: 1565 QSIESKMLELTNRLQESQEEIQIMIKEKEEMKRVQEA 1601
Score = 78.6 bits (192), Expect = 3e-14
Identities = 154/829 (18%), Positives = 316/829 (38%), Gaps = 162/829 (19%)
Query: 184 DEGKSNRHVAVTNMNEHSSRSHSIFLINVKQENTQT--------EQKLSGKLYLVDLAGS 235
D+ K N V M E + + + E + EQ + KL L ++ +
Sbjct: 1607 DQLKENTKEIVAKMKESQEKEYQFLKMTAVNETQEKMCEIEHLKEQFETQKLNLENIE-T 1665
Query: 236 EKVSKTGAEGAVLDEAKNINKSLSALGNVISALAEGSTYVPYRDSKMTRILQDSLGGNCR 295
E + T L+E +++ K L +V L ++ +D L N R
Sbjct: 1666 ENIRLTQILHENLEEMRSVTKERDDLRSVEETL---------------KVERDQLKENLR 1710
Query: 296 TTI-----------VICCSPSSYNESETKSTLLFGQRAKTIKNTVCVNVELTAEQWKKKY 344
TI ++ + E+ K + ++ I N + ++E + + K +
Sbjct: 1711 ETITRDLEKQEELKIVHMHLKEHQETIDKLRGIVSEKTNEISN-MQKDLEHSNDALKAQD 1769
Query: 345 EKEKEKNKILRNTIQWLENELNRWRNGETVPIDEQFDKEKANLEAFTVDKDITLTNDKPA 404
K +E+ +I ++ + +++ R + E+ DK + KD+ +N K
Sbjct: 1770 LKIQEELRIAHMHLKEQQETIDKLRG----IVSEKTDKLS------NMQKDLENSNAKLQ 1819
Query: 405 TAIGVIGNFTDAERRKCEEEIAKLYKQLDDKDEEINQQSQLVEKLKTQMLDQEEL----- 459
I E + E ++ L K +++ +++++ QL +++K Q L +L
Sbjct: 1820 EKI--------QELKANEHQLITLKKDVNETQKKVSEMEQLKKQIKDQSLTLSKLEIENL 1871
Query: 460 ------------LASTRRDQDNMQAELNRLQAENDASKEEV------------------- 488
+ S +++DN++ L+ E D KE +
Sbjct: 1872 NLAQKLHENLEEMKSVMKERDNLRRVEETLKLERDQLKESLQETKARDLEIQQELKTARM 1931
Query: 489 --KEVLQALEELAVNYDQKSQEVEDKTKEYELLSDELNQKSATLASIDAELQKLKEMTNH 546
KE + +++L +K+ ++ D K+ + DEL +K L + +L ++KE N
Sbjct: 1932 LSKEHKETVDKLREKISEKTIQISDIQKDLDKSKDELQKKIQELQKKELQLLRVKEDVNM 1991
Query: 547 QKKRAAEMMASLLKDLAEIGIAVGNNDVKQPEGTGMIDEEFTVARLYISKMKSEVKTMVK 606
K+ E M L K +++ + + + T + E R+ ++K + E++ + +
Sbjct: 1992 SHKKINE-MEQLKKQFEAQNLSMQSVRMDNFQLTKKLHESLEEIRI-VAKERDELRRIKE 2049
Query: 607 RCK----QLESTQTESNKKMEEN-----EKELAA-------------CQLRISQHEAKIK 644
K Q +T E + +N EK L + C RI + +
Sbjct: 2050 SLKMERDQFIATLREMIARDRQNHQVKPEKRLLSDGQQHLTESLREKCS-RIKELLKRYS 2108
Query: 645 SLTEYLQNVEQKKRQLEESVDALSEELVQLRAQEKVHEMEKEHLNKVQTANE-------- 696
+ ++ + + + LE+ ++ E ++++A + ++ +H+ K+ TAN+
Sbjct: 2109 EMDDHYECLNRLSLDLEKEIEFQKELSMRVKANLSLPYLQTKHIEKLFTANQRCSMEFHR 2168
Query: 697 -------VKQAVEQQIQSHRETHQKQISSLRDEVEAKAKLITDLQ--------------- 734
V V + + E+ K DEVE + +L+ +Q
Sbjct: 2169 IMKKLKYVLSYVTKIKEEQHESINKFEMDFIDEVEKQKELLIKIQHLQQDCDVPSRELRD 2228
Query: 735 -DQNQKMMLEQERL-----RVEHEKLKATDQEKSRKLHELTVMQDRREQARQDLKGLEET 788
NQ M L E + E +K Q+ E+T + R D++ L+
Sbjct: 2229 LKLNQNMDLHIEEILKDFSESEFPSIKTEFQQVLSNRKEMTQFLEEWLNTRFDIEKLKNG 2288
Query: 789 VAKELQTLHNLRKLFVQDLATRVKKSAEIDSDDTGGSAAQKQKISFLENNLEQLTKVHKQ 848
+ KE + + F + + +S E + S +Q + L+ E+L K ++
Sbjct: 2289 IQKENDRICQVNNFFNNRIIAIMNESTEFEERSATISKEWEQDLKSLKEKNEKLFKNYQT 2348
Query: 849 LVRDNADLRCELPKLE---------KRLRATAERVKALESALKEAKENA 888
L A P + + + T E+++ LE++L EAKE+A
Sbjct: 2349 LKTSLASGAQVNPTTQDNKNPHVTSRATQLTTEKIRELENSLHEAKESA 2397
Score = 76.3 bits (186), Expect = 1e-13
Identities = 149/713 (20%), Positives = 296/713 (41%), Gaps = 142/713 (19%)
Query: 309 ESETKSTLLFGQRAKTIKNTVCVNVELTAEQWKKKYE-KEKEKNKILRNTIQWLENELNR 367
E E T L TI+N + L ++ KK+ E +EKN ++ E EL+R
Sbjct: 1065 EKEQLKTDLKENIEMTIENQE--ELRLLGDELKKQQEIVAQEKNHAIKK-----EGELSR 1117
Query: 368 WRNGETVPIDEQFDKEKANLEAFTVDKDITLTNDKPATAIGVIGNFTDAERRKCEEEIAK 427
+ ++E+ ++ L+ +K L N + + E +K EI
Sbjct: 1118 TCD-RLAEVEEKLKEKSQQLQ----EKQQQLLNVQEEMS----------EMQKKINEIEN 1162
Query: 428 LYKQLDDKD--------------EEINQQSQLVEKLKTQMLDQEELLASTRRDQDNMQAE 473
L +L +K+ +++N+ + V+ + + +EL S ++D+++
Sbjct: 1163 LKNELKNKELTLEHMETERLELAQKLNENYEEVKSITKERKVLKELQKSFETERDHLRGY 1222
Query: 474 LNRLQAENDASKEEVKEVLQALEELAVNYDQKSQEVEDKT-------------------- 513
+ ++A +KEE+K L+E D+ + V +KT
Sbjct: 1223 IREIEATGLQTKEELKIAHIHLKEHQETIDELRRSVSEKTAQIINTQDLEKSHTKLQEEI 1282
Query: 514 -----------------------KEYELLSDELNQK-SATLASIDAELQKLKEMTNHQKK 549
E ELL+++ K S TLA I+ E +L N + +
Sbjct: 1283 PVLHEEQELLPNVKEVSETQETMNELELLTEQSTTKDSTTLARIEMERLRL----NEKFQ 1338
Query: 550 RAAEMMASLLKDLAEIGIAVGNNDVKQPEGTGMIDEEFTVARLYISKMKSEVKTMVKRCK 609
+ E + SL K+ + +VK + I E T+A++ S+ K E +K K
Sbjct: 1339 ESQEEIKSLTKERDNLKTIKEALEVKHDQLKEHIRE--TLAKIQESQSKQEQSLNMKE-K 1395
Query: 610 QLESTQTES--------NKKMEENEKELAACQLRISQHEAKIKSLTEYLQNVEQKKRQLE 661
E+T+ S + + E E+ R+ + ++KS+ + ++++ + L+
Sbjct: 1396 DNETTKIVSEMEQFKPKDSALLRIEIEMLGLSKRLQESHDEMKSVAKEKDDLQRLQEVLQ 1455
Query: 662 ESVDALSEELVQLRAQ--EKVHEMEKEHL---NKVQTANEVKQAVEQQIQSHRETHQKQI 716
D L E + ++ A+ E E++ H + +T NE++ + ++ ++ T QKQ+
Sbjct: 1456 SESDQLKENIKEIVAKHLETEEELKVAHCCLKEQEETINELRVNLSEK-ETEISTIQKQL 1514
Query: 717 SSLRDEVEAKAKLITDLQDQ-NQKMMLE-QERLR-----VEHEKLK--ATDQEKSRKLHE 767
++ D+++ K + I + ++Q N K + E QE++ EH K K A +S+ L
Sbjct: 1515 EAINDKLQNKIQEIYEKEEQFNIKQISEVQEKVNELKQFKEHRKAKDSALQSIESKMLEL 1574
Query: 768 LTVMQDRREQARQDLKGLEE--TVAKELQTLHNLRKLFVQDLATRVKKSAEIDSDDTGGS 825
+Q+ +E+ + +K EE V + LQ + K +++ ++K+S E + +
Sbjct: 1575 TNRLQESQEEIQIMIKEKEEMKRVQEALQIERDQLKENTKEIVAKMKESQEKEYQFLKMT 1634
Query: 826 AAQ------------KQKISFLENNLEQLTKVH---KQLVRDNADLRCELPKLEKRLRAT 870
A K++ + NLE + + Q++ +N + + K LR+
Sbjct: 1635 AVNETQEKMCEIEHLKEQFETQKLNLENIETENIRLTQILHENLEEMRSVTKERDDLRSV 1694
Query: 871 AERVKALESALKE-AKENASRD-------------RKRYQQEVDRIKEAVRSK 909
E +K LKE +E +RD K +Q+ +D+++ V K
Sbjct: 1695 EETLKVERDQLKENLRETITRDLEKQEELKIVHMHLKEHQETIDKLRGIVSEK 1747
Score = 50.4 bits (119), Expect = 8e-06
Identities = 114/631 (18%), Positives = 255/631 (40%), Gaps = 92/631 (14%)
Query: 326 KNTVCVNVELTAEQWKKKYEKEKEKNKIL---RNTIQWLENELNRWRNGETVPIDEQFDK 382
+N +V + Q KK + E+ +I+ R+ ++ ++ L R+ + E +
Sbjct: 2009 QNLSMQSVRMDNFQLTKKLHESLEEIRIVAKERDELRRIKESLKMERDQFIATLREMIAR 2068
Query: 383 EKANLEAFTVDKDITLTNDKPATAIGVIGNFTDAERRKCE--EEIAKLYKQLDDKDEEIN 440
++ N + V + L +D + T++ R KC +E+ K Y ++DD E +N
Sbjct: 2069 DRQNHQ---VKPEKRLLSDGQQ-------HLTESLREKCSRIKELLKRYSEMDDHYECLN 2118
Query: 441 Q----------------------------QSQLVEKLKTQ-----------MLDQEELLA 461
+ Q++ +EKL T M + +L+
Sbjct: 2119 RLSLDLEKEIEFQKELSMRVKANLSLPYLQTKHIEKLFTANQRCSMEFHRIMKKLKYVLS 2178
Query: 462 STRRDQDNMQAELNRLQAENDASKEEVKEVLQALEELAVNYDQKSQEVEDK--TKEYELL 519
+ ++ +N+ + + E+ KE+L ++ L + D S+E+ D + +L
Sbjct: 2179 YVTKIKEEQHESINKFEMDFIDEVEKQKELLIKIQHLQQDCDVPSRELRDLKLNQNMDLH 2238
Query: 520 SDELNQ--KSATLASIDAELQKLKEMTNHQKKRAAEMMASLLKDLAEIGIAVGNNDVKQP 577
+E+ + + SI E Q++ +K + + L +I + N K+
Sbjct: 2239 IEEILKDFSESEFPSIKTEFQQVLS----NRKEMTQFLEEWLNTRFDIE-KLKNGIQKEN 2293
Query: 578 EGTGMIDEEFTVARLYISKMKSEVK----TMVKRCKQLESTQTESNKKMEENEKEL---- 629
+ ++ F + I +E + T+ K +Q + E N+K+ +N + L
Sbjct: 2294 DRICQVNNFFNNRIIAIMNESTEFEERSATISKEWEQDLKSLKEKNEKLFKNYQTLKTSL 2353
Query: 630 -AACQLRISQHEAKIKSLTEYL-QNVEQKKRQLEESVDALSEELVQLRAQEKVHEMEKEH 687
+ Q+ + + K +T Q +K R+LE S+ E + + K+ +M+KE
Sbjct: 2354 ASGAQVNPTTQDNKNPHVTSRATQLTTEKIRELENSLHEAKESA--MHKESKIIKMQKE- 2410
Query: 688 LNKVQTANEVKQAVEQQIQSHRETHQKQ---ISSLRDEVEAKAKLITD-LQDQNQKMM-L 742
++ N++ ++ ++ + +K I L+D+V AK + ++D K++ +
Sbjct: 2411 ---LEVTNDIIAKLQAKVHESNKCLEKTKETIQVLQDKVALGAKPYKEEIEDLKMKLVKI 2467
Query: 743 EQERLRVEHEKLKATDQEKSRKLHELTVMQDRREQARQDLKGLEETVAKELQTLHNLRKL 802
+ E+++ E K K+ ++ V++ RE R+ + + +V E K
Sbjct: 2468 DLEKMKNAKEFEKEISATKATVEYQKEVIRLLRENLRRSQQAQDTSVISEHTDPQPSNKP 2527
Query: 803 FVQDLATRVKKSAEIDSDDTGGSAAQKQKISFLENNLEQLTKVHKQLVRDNADLRCELPK 862
+ + ++ + + K + LE + +L + ++QL++ +L
Sbjct: 2528 LTCGGGSGIVQNTK--------ALILKSEHIRLEKEISKLKQQNEQLIKQKNELLSNNQH 2579
Query: 863 LEKRLRATAERVKALESALKEAKENASRDRK 893
L ++ ER E+ + EN+ + K
Sbjct: 2580 LSNEVKTWKERTLKREAHKQVTCENSPKSPK 2610
>gi|116686122 kinesin family member 4 [Homo sapiens]
Length = 1232
Score = 290 bits (742), Expect = 4e-78
Identities = 262/958 (27%), Positives = 454/958 (47%), Gaps = 94/958 (9%)
Query: 9 IKVMCRFRPLNESEVNRGDKYIAKF-QGEDTVVIAS-KPYAFDRVFQSSTSQEQVYNDCA 66
++V R RPL E++ G + F GE VV+ + K + +D VF ST QE+V+N
Sbjct: 10 VRVALRCRPLVPKEISEGCQMCLSFVPGEPQVVVGTDKSFTYDFVFDPSTEQEEVFNTAV 69
Query: 67 KKIVKDVLEGYNGTIFAYGQTSSGKTHTMEG----KLHDPEGMGIIPRIVQDIFNYIYSM 122
++K V +GYN T+ AYGQT SGKT++M G + + +G+IPR++Q +F I
Sbjct: 70 APLIKGVFKGYNATVLAYGQTGSGKTYSMGGAYTAEQENEPTVGVIPRVIQLLFKEI-DK 128
Query: 123 DENLEFHIKVSYFEIYLDKIRDLLDVS--KTNLSVHEDKNRVPYVKGCTERFVCSPDEVM 180
+ EF +KVSY EIY ++I DLL S K +++ ED + G TE+ V + +
Sbjct: 129 KSDFEFTLKVSYLEIYNEEILDLLCPSREKAQINIREDPKEGIKIVGLTEKTVLVALDTV 188
Query: 181 DTIDEGKSNRHVAVTNMNEHSSRSHSIFLINVKQ-ENTQTEQKLSGKLYLVDLAGSEKVS 239
+++G ++R VA T MN SSRSH+IF I+++Q + + KL+LVDLAGSE+
Sbjct: 189 SCLEQGNNSRTVASTAMNSQSSRSHAIFTISLEQRKKSDKNSSFRSKLHLVDLAGSERQK 248
Query: 240 KTGAEGAVLDEAKNINKSLSALGNVISALAEGST--YVPYRDSKMTRILQDSLGGNCRTT 297
KT AEG L E NIN+ L LGNVISAL + +VPYRDSK+TR+LQDSLGGN T
Sbjct: 249 KTKAEGDRLKEGININRGLLCLGNVISALGDDKKGGFVPYRDSKLTRLLQDSLGGNSHTL 308
Query: 298 IVICCSPSSYNESETKSTLLFGQRAKTIKNTVCVNVE-LTAEQWKKKYEKEKEKNKILRN 356
++ C SP+ N ET +TL + RA+ IKN VN++ TAE K + ++ + +L+
Sbjct: 309 MIACVSPADSNLEETLNTLRYADRARKIKNKPIVNIDPQTAELNHLKQQVQQLQVLLLQA 368
Query: 357 ---------TIQWLEN-ELNRWRNGETVPIDEQFDK---EKANLEAFTVDKDITL--TND 401
T++ EN + +N V +E+ + E A A +++ I N+
Sbjct: 369 HGGTLPGSITVEPSENLQSLMEKNQSLVEENEKLSRGLSEAAGQTAQMLERIILTEQANE 428
Query: 402 KPATAIGVIGNFTDAERRKCEEEIAKLYKQLDDKDEEINQQSQLV---EKLKTQMLD--- 455
K + + + C+ ++ KL + L+ D+E+ + +++ ++L TQ+ D
Sbjct: 429 KMNAKLEEL-----RQHAACKLDLQKLVETLE--DQELKENVEIICNLQQLITQLSDETV 481
Query: 456 ---------------QEELLASTRRDQDNMQAELNRLQAENDASKEEVKEVLQALEELAV 500
Q E T R D + QA+ E+ + L E LA
Sbjct: 482 ACMAAAIDTAVEQEAQVETSPETSRSSDAFTTQHALRQAQMSKELVELNKALALKEALAR 541
Query: 501 NYDQKSQEVEDKTKEYELLSDELNQKSATLASIDAELQKLKEMTNHQKKRA--AEMMASL 558
Q +++ +Y+ D + + + ++ E ++L KK A A++
Sbjct: 542 KMTQNDSQLQPIQYQYQ---DNIKELELEVINLQKEKEELVLELQTAKKDANQAKLSERR 598
Query: 559 LKDLAEIGIAVGNNDVKQPEGTGMIDEEFTVARLYISKMKSEVKTMVKRCKQLESTQTES 618
K L E+ + + K E + ++ + + R +SK+ E++ M + QL E
Sbjct: 599 RKRLQELEGQIADLKKKLNEQSKLLKLKESTERT-VSKLNQEIRMMKNQRVQLMRQMKED 657
Query: 619 NKKM----EENEKELAACQLRISQHEAKIKSLTEYLQNVEQKKRQLEESVDALSEELVQ- 673
+K ++ +KE+ + R + + ++ L Q R+ E A ++ L
Sbjct: 658 AEKFRQWKQKKDKEVIQLKERDRKRQYELLKLERNFQKQSNVLRRKTEEAAAANKRLKDA 717
Query: 674 LRAQEKVHEMEKEHLNKVQ--TANEVKQAVEQQIQSHRETHQKQISSLRDEVEAKAKLIT 731
L+ Q +V + KE ++ TA VK + +I+ T EAK L
Sbjct: 718 LQKQREVADKRKETQSRGMEGTAARVKNWLGNEIEVMVSTE-----------EAKRHL-N 765
Query: 732 DLQDQNQKMMLEQERLRVEHEKLKATDQEKSRKLHELTVMQDRREQARQDLKGLEETVAK 791
DL + + + + +L+ + E + + R+ LT + R + E+++ K
Sbjct: 766 DLLEDRKILAQDVAQLKEKKESGENPPPKLRRRTFSLT-------EVRGQVSESEDSITK 818
Query: 792 ELQTLHNLRKLFVQDLATRVKKSAEIDSDDTGGSAAQKQKISFLENNLEQLTKVHKQLVR 851
++++L + +A +K + +S+D KQ+ + LE + K L+
Sbjct: 819 QIESLETEMEFRSAQIADLQQKLLDAESED-----RPKQRWENIATILEAKCAL-KYLIG 872
Query: 852 DNADLRCELPKLEKRLRATAERVKALESALKEAKENASRDRKRYQQEVDRIKEAVRSK 909
+ + ++ KLE L+ + ++ L E + + + Q E+ R+++ + K
Sbjct: 873 ELVSSKIQVSKLESSLKQSKTSCADMQKMLFEERNHFAEIETELQAELVRMEQQHQEK 930
Score = 69.7 bits (169), Expect = 1e-11
Identities = 83/373 (22%), Positives = 162/373 (43%), Gaps = 47/373 (12%)
Query: 339 QWKKKYEKEKEKNKILRNTIQWLENELNRWRNGETVPIDEQFDKEKANLEAFTVDKDITL 398
QWK+K +KE + K E +R R E + ++ F K+ L T ++
Sbjct: 663 QWKQKKDKEVIQLK-----------ERDRKRQYELLKLERNFQKQSNVLRRKT--EEAAA 709
Query: 399 TNDKPATAIG----VIGNFTDAERRKCEEEIAKLYKQLDDKDEEINQQSQLVEKLKTQML 454
N + A+ V + + R E A++ L + + E+ ++ ++ +L
Sbjct: 710 ANKRLKDALQKQREVADKRKETQSRGMEGTAARVKNWLGN-EIEVMVSTEEAKRHLNDLL 768
Query: 455 DQEELLASTRRDQDNMQAELNRLQAENDASKEEVKEVLQALEELAVNYDQKSQEVEDKTK 514
+ ++LA QD Q + + EN K ++ +L E+ Q S+ + TK
Sbjct: 769 EDRKILA-----QDVAQLKEKKESGENPPPK--LRRRTFSLTEVR---GQVSESEDSITK 818
Query: 515 EYELLSDELNQKSATLASIDAELQKLKEMTNHQKKRAAEMMASLLKDLAEIGIAVGNNDV 574
+ E L E+ +SA +A + +L L + + K+ E +A++L+ + +G
Sbjct: 819 QIESLETEMEFRSAQIADLQQKL--LDAESEDRPKQRWENIATILEAKCALKYLIG---- 872
Query: 575 KQPEGTGMIDEEFTVARLYISKMKSEVKTMVKRCKQLESTQTESNKKMEENEKELAACQL 634
E +++ +SK++S +K C ++ E E E EL A +
Sbjct: 873 -----------ELVSSKIQVSKLESSLKQSKTSCADMQKMLFEERNHFAEIETELQAELV 921
Query: 635 RISQ-HEAKIKSLTEYLQNVEQKKRQLEESVDALSEELVQ-LRAQEKVHEMEKEHLNKVQ 692
R+ Q H+ K+ L LQ + ++QLEESV ++L+ L+ Q++ E +E + Q
Sbjct: 922 RMEQQHQEKVLYLLSQLQQSQMAEKQLEESVSEKEQQLLSTLKCQDEELEKMREVCEQNQ 981
Query: 693 TANEVKQAVEQQI 705
+ ++Q++
Sbjct: 982 QLLRENEIIKQKL 994
Score = 61.2 bits (147), Expect = 4e-09
Identities = 91/510 (17%), Positives = 216/510 (42%), Gaps = 44/510 (8%)
Query: 423 EEIAKLYKQLDDKDEEINQQSQLVEKLKTQMLDQEELLASTRRDQDNMQAELNRLQAEND 482
+E+ +L K L K+ + +Q +L+ ++ + + N+Q E L E
Sbjct: 524 KELVELNKALALKEALARKMTQNDSQLQPIQYQYQDNIKELELEVINLQKEKEELVLELQ 583
Query: 483 ASKEEVKEVLQALEELAVNYDQKSQEVEDKTKEYELLSDELNQKSATLA---SIDAELQK 539
+K++ + +L+ ++ QE+E + + L +LN++S L S + + K
Sbjct: 584 TAKKDANQA-----KLSERRRKRLQELEGQIAD---LKKKLNEQSKLLKLKESTERTVSK 635
Query: 540 LKEMTNHQKKRAAEMMASLLKDLAEIG----------IAVGNNDVKQPEGTGMIDEEFTV 589
L + K + ++M + +D + I + D K+ ++ F
Sbjct: 636 LNQEIRMMKNQRVQLMRQMKEDAEKFRQWKQKKDKEVIQLKERDRKRQYELLKLERNFQK 695
Query: 590 ARLYISKMKSEVKTMVKRCKQLESTQTE-SNKKMEENEKELAACQLRISQHEAKIKSLTE 648
+ + E KR K Q E ++K+ E + + R+ + + E
Sbjct: 696 QSNVLRRKTEEAAAANKRLKDALQKQREVADKRKETQSRGMEGTAARVKNW---LGNEIE 752
Query: 649 YLQNVEQKKRQLEESVD---ALSEELVQLRAQEKVHEMEKEHLNKVQTANEVKQAVEQQI 705
+ + E+ KR L + ++ L++++ QL+ +++ E L + +T + + V Q+
Sbjct: 753 VMVSTEEAKRHLNDLLEDRKILAQDVAQLKEKKESGENPPPKLRR-RTFSLTE--VRGQV 809
Query: 706 QSHRETHQKQISSLRDEVEAKAKLITDLQDQNQKMM--LEQERLRVEHEKLKATDQEKSR 763
++ KQI SL E+E ++ I DLQ QK++ ++R + E + + K
Sbjct: 810 SESEDSITKQIESLETEMEFRSAQIADLQ---QKLLDAESEDRPKQRWENIATILEAKCA 866
Query: 764 KLHELTVMQDRREQARQDLKGLEETVAKELQTLHNLRKLFVQDLATRVKKSAEIDSDDTG 823
+ + + + Q + LE ++ + + +++K+ ++ + E+ ++
Sbjct: 867 LKYLIGELVSSKIQVSK----LESSLKQSKTSCADMQKMLFEERNHFAEIETELQAELVR 922
Query: 824 GSAAQKQKISFLENNLEQLTKVHKQLVRDNADLRCELPKLEKRLRATAERVKALESALKE 883
++K+ +L + L+Q KQL ++ + +L L+ E ++ + E
Sbjct: 923 MEQQHQEKVLYLLSQLQQSQMAEKQLEESVSE---KEQQLLSTLKCQDEELEKMREVC-E 978
Query: 884 AKENASRDRKRYQQEVDRIKEAVRSKNMAR 913
+ R+ + +Q++ ++ A R K++ +
Sbjct: 979 QNQQLLRENEIIKQKLTLLQVASRQKHLPK 1008
>gi|46852174 kinesin family member 3A [Homo sapiens]
Length = 699
Score = 290 bits (741), Expect = 6e-78
Identities = 212/564 (37%), Positives = 301/564 (53%), Gaps = 40/564 (7%)
Query: 8 NIKVMCRFRPLNESEVNRGDKY---IAKFQGEDTVVIAS------KPYAFDRVFQSSTSQ 58
N+KV+ R RPLNE E + K + + +G TV K + FD VF + Q
Sbjct: 14 NVKVVVRCRPLNEREKSMCYKQAVSVDEMRGTITVHKTDSSNEPPKTFTFDTVFGPESKQ 73
Query: 59 EQVYNDCAKKIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPEGMGIIPRIVQDIFNY 118
VYN A+ I+ VLEGYNGTIFAYGQT +GKT TMEG PE GIIP IF +
Sbjct: 74 LDVYNLTARPIIDSVLEGYNGTIFAYGQTGTGKTFTMEGVRAIPELRGIIPNSFAHIFGH 133
Query: 119 IYSMDENLEFHIKVSYFEIYLDKIRDLLDVSKT-NLSVHEDKNRVPYVKGCTERFVCSPD 177
I + + F ++VSY EIY +++RDLL +T L V E + Y+K + V + D
Sbjct: 134 IAKAEGDTRFLVRVSYLEIYNEEVRDLLGKDQTQRLEVKERPDVGVYIKDLSAYVVNNAD 193
Query: 178 EVMDTIDEGKSNRHVAVTNMNEHSSRSHSIFLINVKQENTQTEQKL---SGKLYLVDLAG 234
++ + G NR V TNMNEHSSRSH+IF I ++ + + GKL+LVDLAG
Sbjct: 194 DMDRIMTLGHKNRSVGATNMNEHSSRSHAIFTITIECSEKGIDGNMHVRMGKLHLVDLAG 253
Query: 235 SEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAEG-STYVPYRDSKMTRILQDSLGGN 293
SE+ +KTGA G L EA IN SLS LGNVISAL +G ST+VPYR+SK+TR+LQDSLGGN
Sbjct: 254 SERQAKTGATGQRLKEATKINLSLSTLGNVISALVDGKSTHVPYRNSKLTRLLQDSLGGN 313
Query: 294 CRTTIVICCSPSSYNESETKSTLLFGQRAKTIKNTVCVN---VELTAEQWKKKYEKEKEK 350
+T + P+ YN ET STL + RAK IKN +N + Q++K+ E+ K+K
Sbjct: 314 SKTMMCANIGPADYNYDETISTLRYANRAKNIKNKARINEDPKDALLRQFQKEIEELKKK 373
Query: 351 ----NKILRNTIQWLENELNRWRNGETVPIDEQFDKEKANLEAFTVDKDITLTN--DKPA 404
+I + I E + + GE V D + K++ + + DK I + D+
Sbjct: 374 LEEGEEISGSDISGSEEDDD--EEGE-VGEDGEKRKKRRGKKKVSPDKMIEMQAKIDEER 430
Query: 405 TAIGVIGNFTDAERRKCEEEIAKLYKQLDDKDEEINQQSQLVEKL----KTQMLDQEELL 460
A+ + + ER K E+ K K L +E L+EKL K ++ +LL
Sbjct: 431 KALETKLDMEEEERNKARAELEKREKDLLKAQQE---HQSLLEKLSALEKKVIVGGVDLL 487
Query: 461 ASTRR-----DQDNMQAELNRLQAENDASKEEVKEVLQALEELAVNYDQKSQEVEDKTKE 515
A ++ NM+ E R +AE + E++E Q ++ Y +E + KTK+
Sbjct: 488 AKAEEQEKLLEESNMELEERRKRAEQ--LRRELEEKEQERLDIEEKYTSLQEEAQGKTKK 545
Query: 516 YELLSDELNQKSATLASIDAELQK 539
+ + L + +A + E Q+
Sbjct: 546 LKKVWTMLMAAKSEMADLQQEHQR 569
Score = 42.4 bits (98), Expect = 0.002
Identities = 67/354 (18%), Positives = 139/354 (39%), Gaps = 20/354 (5%)
Query: 394 KDITLTNDKPATAIGVIGNFTDAERRKCEEEIAKLYKQLDDKDEEINQQSQLVEKLKTQM 453
K+ T N +T VI D + +KL + L D N ++ + +
Sbjct: 268 KEATKINLSLSTLGNVISALVDGKSTHVPYRNSKLTRLLQDSLGG-NSKTMMCANIGPAD 326
Query: 454 LDQEELLASTRRDQDNMQAELNRLQAENDASKEEVKEVLQALEELAVNYDQKSQEVEDKT 513
+ +E + ST R + + N+ + D +++ + +EEL +K E ++
Sbjct: 327 YNYDETI-STLRYANRAKNIKNKARINEDPKDALLRQFQKEIEEL-----KKKLEEGEEI 380
Query: 514 KEYELLSDELNQKSATLASIDAELQKLKEMTNHQKKRAAEMMASLLKDLAEIGIAVGNND 573
++ E + D E +K + +KK + + M + + E A+
Sbjct: 381 SGSDISGSEEDDDEEGEVGEDGEKRKKRR---GKKKVSPDKMIEMQAKIDEERKALETKL 437
Query: 574 VKQPEGTGMIDEEFTVARLYISKMKSEVKTMVKRCKQLESTQTESN----KKMEENEKEL 629
+ E E + K + E ++++++ LE K EE EK L
Sbjct: 438 DMEEEERNKARAELEKREKDLLKAQQEHQSLLEKLSALEKKVIVGGVDLLAKAEEQEKLL 497
Query: 630 AACQLRISQHEAKIKSLTEYLQNVEQKKRQLEESVDALSEELVQLRAQEKVHEMEKEHLN 689
+ + + + + L L+ EQ++ +EE +L EE AQ K +++K
Sbjct: 498 EESNMELEERRKRAEQLRRELEEKEQERLDIEEKYTSLQEE-----AQGKTKKLKKVWTM 552
Query: 690 KVQTANEVKQAVEQQIQSHRETHQKQISSLRDEVEAKAKLITDLQDQNQKMMLE 743
+ +E+ ++Q+ Q E + I L E+ + +I + ++ + M+E
Sbjct: 553 LMAAKSEMAD-LQQEHQREIEGLLENIRQLSRELRLQMLIIDNFIPRDYQEMIE 605
Score = 40.0 bits (92), Expect = 0.010
Identities = 49/266 (18%), Positives = 120/266 (45%), Gaps = 38/266 (14%)
Query: 651 QNVEQKKRQLEESVDALSEELVQLRAQEKVHEMEKEHLNKVQTANEVKQAVEQQIQSHRE 710
+N++ K R E+ DAL + Q+++ E++K K++ E+ + I E
Sbjct: 343 KNIKNKARINEDPKDALLRQF-----QKEIEELKK----KLEEGEEISGS---DISGSEE 390
Query: 711 THQKQISSLRDEVEAKAKLITDLQDQNQKMMLEQERLRVEHEKLKATDQEKSRKLHELTV 770
++ + ++ E + K + KM+ Q ++ E + L+ +L +
Sbjct: 391 DDDEE-GEVGEDGEKRKKRRGKKKVSPDKMIEMQAKIDEERKALET----------KLDM 439
Query: 771 MQDRREQARQDLKGLEETVAKELQTLHNLRKLFVQDLATRVKKSAEIDSDDTGGSAAQKQ 830
++ R +AR +L+ E+ + K Q +L + + ++K + D A +++
Sbjct: 440 EEEERNKARAELEKREKDLLKAQQEHQSL-----LEKLSALEKKVIVGGVDLLAKAEEQE 494
Query: 831 KISFLENNL---------EQLTKVHKQLVRDNADLRCELPKLEKRLRATAERVKALESAL 881
K+ E+N+ EQL + ++ ++ D+ + L++ + +++K + + L
Sbjct: 495 KL-LEESNMELEERRKRAEQLRRELEEKEQERLDIEEKYTSLQEEAQGKTKKLKKVWTML 553
Query: 882 KEAKENASRDRKRYQQEVDRIKEAVR 907
AK + ++ +Q+E++ + E +R
Sbjct: 554 MAAKSEMADLQQEHQREIEGLLENIR 579
Score = 38.1 bits (87), Expect = 0.040
Identities = 52/246 (21%), Positives = 117/246 (47%), Gaps = 33/246 (13%)
Query: 609 KQLESTQTESNKKMEENEKELAACQLRISQHEAKIKSLTEYLQNVEQKKRQLEE---SVD 665
+Q + E KK+EE E E++ + S+ + + E ++ E++K++ + S D
Sbjct: 361 RQFQKEIEELKKKLEEGE-EISGSDISGSEEDDDEEG--EVGEDGEKRKKRRGKKKVSPD 417
Query: 666 ALSEELVQLRAQEKVHE----MEKEHLNKVQTANEVKQAVEQQIQSHRETHQKQISSLRD 721
+ E ++ + K E ME+E NK + E ++ + Q ++ +++S+L
Sbjct: 418 KMIEMQAKIDEERKALETKLDMEEEERNKARAELEKREKDLLKAQQEHQSLLEKLSALEK 477
Query: 722 EVEAKAKLITDL--QDQNQKMMLEQERLRVEHEKLKATDQEKSRKLHELTVMQDRREQAR 779
+V DL + + Q+ +LE+ + +E + +A ++ R+L E +EQ R
Sbjct: 478 KVIVGG---VDLLAKAEEQEKLLEESNMELEERRKRA--EQLRRELEE-------KEQER 525
Query: 780 QDLKGLEETVAKELQ-TLHNLRKLFVQDLATRVKKSAEIDSDDTGGSAAQKQKISFLENN 838
D++ ++ +E Q L+K++ +A + + A++ + +++I L N
Sbjct: 526 LDIEEKYTSLQEEAQGKTKKLKKVWTMLMAAK-SEMADLQQE-------HQREIEGLLEN 577
Query: 839 LEQLTK 844
+ QL++
Sbjct: 578 IRQLSR 583
>gi|4758646 kinesin family member 3B [Homo sapiens]
Length = 747
Score = 282 bits (722), Expect = 9e-76
Identities = 203/578 (35%), Positives = 305/578 (52%), Gaps = 37/578 (6%)
Query: 8 NIKVMCRFRPLNESE------------VNRGDKYIAKFQGEDTVVIASKPYAFDRVFQSS 55
+++V+ R RP+N E V G + +G T K + FD V+ +
Sbjct: 9 SVRVVVRCRPMNGKEKAASYDKVVDVDVKLGQVSVKNPKG--TAHEMPKTFTFDAVYDWN 66
Query: 56 TSQEQVYNDCAKKIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPEGMGIIPRIVQDI 115
Q ++Y++ + +V VL+G+NGTIFAYGQT +GKT+TMEG DPE G+IP I
Sbjct: 67 AKQFELYDETFRPLVDSVLQGFNGTIFAYGQTGTGKTYTMEGIRGDPEKRGVIPNSFDHI 126
Query: 116 FNYIYSMDENLEFHIKVSYFEIYLDKIRDLLDVSKT-NLSVHEDKNRVPYVKGCTERFVC 174
F +I S +N ++ ++ SY EIY ++IRDLL +T L + E + YVK +
Sbjct: 127 FTHI-SRSQNQQYLVRASYLEIYQEEIRDLLSKDQTKRLELKERPDTGVYVKDLSSFVTK 185
Query: 175 SPDEVMDTIDEGKSNRHVAVTNMNEHSSRSHSIFLINVKQENTQTEQK---LSGKLYLVD 231
S E+ ++ G NR V TNMNEHSSRSH+IF+I ++ + + GKL LVD
Sbjct: 186 SVKEIEHVMNVGNQNRSVGATNMNEHSSRSHAIFVITIECSEVGLDGENHIRVGKLNLVD 245
Query: 232 LAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAEG-STYVPYRDSKMTRILQDSL 290
LAGSE+ +KTGA+G L EA IN SLSALGNVISAL +G ST++PYRDSK+TR+LQDSL
Sbjct: 246 LAGSERQAKTGAQGERLKEATKINLSLSALGNVISALVDGKSTHIPYRDSKLTRLLQDSL 305
Query: 291 GGNCRTTIVICCSPSSYNESETKSTLLFGQRAKTIKNTVCVNVELTAEQWKKKYEKE--K 348
GGN +T +V P+SYN ET +TL + RAK IKN VN E + +++++E +
Sbjct: 306 GGNAKTVMVANVGPASYNVEETLTTLRYANRAKNIKNKPRVN-EDPKDALLREFQEEIAR 364
Query: 349 EKNKILRNTIQWLENELNRWRNGETVPIDEQFDKEKANLEAFTVDKDITLTNDKPATAIG 408
K ++ + +I + R G + E+ ++E E DKD + I
Sbjct: 365 LKAQLEKRSIGRRKRREKRREGGGSGGGGEEEEEEGEEGEEEGDDKDDYWREQQEKLEIE 424
Query: 409 VIGNFTDAERRKCEEEIAKLYKQLDDKDEEINQQSQLVEKLKTQMLDQE-ELLASTRRDQ 467
D EE +L K+ + K E++ ++ E L ++ E +LL +
Sbjct: 425 KRAIVED--HSLVAEEKMRLLKEKEKKMEDLRREKDAAEMLGAKIKAMESKLLVGGKNIV 482
Query: 468 DN---MQAELNRLQAENDASKEEVKEVLQALE-------ELAVNYDQKSQEVEDKTKEYE 517
D+ Q L + + E K +E+ Q +E EL Y QEV+ KTK+ +
Sbjct: 483 DHTNEQQKILEQKRQEIAEQKRREREIQQQMESRDEETLELKETYSSLQQEVDIKTKKLK 542
Query: 518 LLSDELNQKSATLASIDAE-LQKLKEMTNHQKKRAAEM 554
L +L A + + E +++ +E+ Q + E+
Sbjct: 543 KLFSKLQAVKAEIHDLQEEHIKERQELEQTQNELTREL 580
Score = 41.6 bits (96), Expect = 0.004
Identities = 50/272 (18%), Positives = 116/272 (42%), Gaps = 35/272 (12%)
Query: 651 QNVEQKKRQLEESVDAL----SEELVQLRAQEKVHEMEKEHLNKVQTANEVKQAVEQQIQ 706
+N++ K R E+ DAL EE+ +L+AQ +EK + + + + ++
Sbjct: 338 KNIKNKPRVNEDPKDALLREFQEEIARLKAQ-----LEKRSIGRRKRREKRREGGGSGGG 392
Query: 707 SHRETHQKQISSLRDEVEAKAKLITDLQDQNQKMMLEQERLRVEHEKLKATDQ-----EK 761
E + + E E + D + Q+ + ++R VE L A ++ EK
Sbjct: 393 GEEEEEEGE------EGEEEGDDKDDYWREQQEKLEIEKRAIVEDHSLVAEEKMRLLKEK 446
Query: 762 SRKLHELTVMQDRREQARQDLKGLEETVAKELQTLHNLRKLFV--QDLATRVKKSAEIDS 819
+K+ +L +D E +K +E KL V +++ + +I
Sbjct: 447 EKKMEDLRREKDAAEMLGAKIKAMES-------------KLLVGGKNIVDHTNEQQKILE 493
Query: 820 DDTGGSAAQKQKISFLENNLEQLTKVHKQLVRDNADLRCELPKLEKRLRATAERVKALES 879
A QK++ ++ +E + +L + L+ E+ K+L+ +++A+++
Sbjct: 494 QKRQEIAEQKRREREIQQQMESRDEETLELKETYSSLQQEVDIKTKKLKKLFSKLQAVKA 553
Query: 880 ALKEAKENASRDRKRYQQEVDRIKEAVRSKNM 911
+ + +E ++R+ +Q + + ++ K++
Sbjct: 554 EIHDLQEEHIKERQELEQTQNELTRELKLKHL 585
Score = 40.0 bits (92), Expect = 0.010
Identities = 52/269 (19%), Positives = 117/269 (43%), Gaps = 33/269 (12%)
Query: 586 EFTVARLYISKMKSEVKTMVKRCKQLESTQTESNKKMEENEKELAACQLRISQHEAKIKS 645
E A + +K+K+ ++ K + E K +E+ +E+A + R + + +++S
Sbjct: 456 EKDAAEMLGAKIKAMESKLLVGGKNIVDHTNEQQKILEQKRQEIAEQKRREREIQQQMES 515
Query: 646 LTEYLQNVEQKKRQLEESVDALSEELVQL-----RAQEKVHEMEKEHLNK----VQTANE 696
E +++ L++ VD +++L +L + ++H++++EH+ + QT NE
Sbjct: 516 RDEETLELKETYSSLQQEVDIKTKKLKKLFSKLQAVKAEIHDLQEEHIKERQELEQTQNE 575
Query: 697 ------VKQAVEQQIQSHRETHQKQISSLRDEVEAKAKLITDLQDQNQKMM------LEQ 744
+K + + E + + DE E KL + +NQ+MM +
Sbjct: 576 LTRELKLKHLIIENFIPLEEKSKIMNRAFFDEEEDHWKLHPITRLENQQMMKRPVSAVGY 635
Query: 745 ERLRVEHEKLKATDQEKSRKLHELTVM--QDRREQARQDLKGLEETVAKELQTLHNLRKL 802
+R +H ++ + ++R E V+ D + +D +G +A ++Q
Sbjct: 636 KRPLSQHARMSMMIRPEARYRAENIVLLELDMPSRTTRDYEG--PAIAPKVQA------- 686
Query: 803 FVQDLATRVKKSAEIDSDDTGGSAAQKQK 831
D A + + ++D+ +A +K K
Sbjct: 687 -ALDAALQDEDEIQVDASSFESTANKKSK 714
>gi|150010604 kinesin family member 4B [Homo sapiens]
Length = 1234
Score = 280 bits (716), Expect = 5e-75
Identities = 261/956 (27%), Positives = 446/956 (46%), Gaps = 90/956 (9%)
Query: 9 IKVMCRFRPLNESEVNRGDKYIAKF-QGEDTVVIAS-KPYAFDRVFQSSTSQEQVYNDCA 66
++V R RPL E++ G + F GE VV+ + K + +D VF T QE+V+N
Sbjct: 10 VRVALRCRPLVPKEISEGCQMCLSFVPGETQVVVGTDKSFTYDFVFDPCTEQEEVFNKAV 69
Query: 67 KKIVKDVLEGYNGTIFAYGQTSSGKTHTMEG----KLHDPEGMGIIPRIVQDIFNYIYSM 122
++K + +GYN T+ AYGQT SGKT++M G + + +GIIPR++Q +F I
Sbjct: 70 APLIKGIFKGYNATVLAYGQTGSGKTYSMGGAYTAEQENEPTVGIIPRVIQLLFKEI-DK 128
Query: 123 DENLEFHIKVSYFEIYLDKIRDLLDVS--KTNLSVHEDKNRVPYVKGCTERFVCSPDEVM 180
+ EF +KVSY EIY ++I DLL S K +++ ED + G TE+ V + +
Sbjct: 129 KSDFEFTLKVSYLEIYNEEILDLLCPSREKAQINIREDPKEGIKIVGLTEKTVLVALDTV 188
Query: 181 DTIDEGKSNRHVAVTNMNEHSSRSHSIFLINVKQENTQTEQ-KLSGKLYLVDLAGSEKVS 239
+++G ++R VA T MN SSRSH+IF I+++Q + KL+LVDLAGSE+
Sbjct: 189 SCLEQGNNSRTVASTAMNSQSSRSHAIFTISIEQRKKSDKNCSFRSKLHLVDLAGSERQK 248
Query: 240 KTGAEGAVLDEAKNINKSLSALGNVISALAEGS--TYVPYRDSKMTRILQDSLGGNCRTT 297
KT AEG L E NIN+ L LGNVISAL + ++VPYRDSK+TR+LQDSLGGN T
Sbjct: 249 KTKAEGDRLKEGININRGLLCLGNVISALGDDKKGSFVPYRDSKLTRLLQDSLGGNSHTL 308
Query: 298 IVICCSPSSYNESETKSTLLFGQRAKTIKNTVCVNVE-LTAEQWKKKYEKEKEKNKILRN 356
++ C SP+ N ET STL + RA+ IKN VN++ TAE K + ++ + +L+
Sbjct: 309 MIACVSPADSNLEETLSTLRYADRARKIKNKPIVNIDPHTAELNHLKQQVQQLQVLLLQA 368
Query: 357 TIQWLENELN----------RWRNGETVPIDEQFDK--EKANLEAFTVDKDITLT---ND 401
L +N +N V +E+ + KA + + + I LT N+
Sbjct: 369 HGGTLPGSINAEPSENLQSLMEKNQSLVEENEKLSRCLSKAAGQTAQMLERIILTEQVNE 428
Query: 402 KPATAIGVIGNFTDAERRKCEEEIAKLYKQLDDKDEEINQQSQLV---EKLKTQMLD--- 455
K + + + C+ ++ KL + L+ D+E+ + +++ ++L TQ+ D
Sbjct: 429 KLNAKLEEL-----RQHVACKLDLQKLVETLE--DQELKENVEIICNLQQLITQLSDETV 481
Query: 456 ---------------QEELLASTRRDQDNMQAELNRLQAENDASKEEVKEVLQALEELAV 500
Q E T R D + QA+ E+ L E L
Sbjct: 482 ACTAAAIDTAVEEEAQVETSPETSRSSDAFTTQHALHQAQMSKEVVELNNALALKEALVR 541
Query: 501 NYDQKSQEVEDKTKEYELLSDELNQKSATLASIDAELQKLKEMTNHQKKRA--AEMMASL 558
Q +++ +Y+ D + + ++ E ++L KK A++
Sbjct: 542 KMTQNDNQLQPIQFQYQ---DNIKNLELEVINLQKEKEELVRELQTAKKNVNQAKLSEHR 598
Query: 559 LKDLAEIGIAVGNNDVKQPEGTGMIDEEFTVARLYISKMKSEVKTMVKRCKQLESTQTES 618
K L E+ + + K E + ++ + + R +SK+ E+ M + QL E
Sbjct: 599 HKLLQELEGQIADLKKKLNEQSKLLKLKESTERT-VSKLNQEIWMMKNQRVQLMRQMKED 657
Query: 619 NKKM----EENEKELAACQLRISQHEAKIKSLTEYLQNVEQKKRQLEESVDALSEELVQ- 673
+K ++ +KE+ + R + + ++ L Q R+ E A ++ L
Sbjct: 658 AEKFRQWKQKKDKEVIQLKERDRKRQYELLKLERNFQKQSSVLRRKTEEAAAANKRLKDA 717
Query: 674 LRAQEKVHEMEKEHLNKVQTANEVKQAVEQQIQSHRETHQKQISSLRDEVEAKAKLITDL 733
L+ Q +V + KE T + K+ + ++ R +I + EAK L L
Sbjct: 718 LQKQREVTDKRKE------TQSHGKEGIAARV---RNWLGNEIEVMVSTEEAKRHLNDLL 768
Query: 734 QDQNQKMMLEQERLRVEHEKLKATDQEKSRKLHELTVMQDRREQARQDLKGLEETVAKEL 793
+D + +L Q+ ++++ + K + + KL + T + + E+ + K++
Sbjct: 769 ED---RKILAQDVVQLKEK--KESRENPPPKLRKCTF---SLSEVHGQVLESEDCITKQI 820
Query: 794 QTLHNLRKLFVQDLATRVKKSAEIDSDDTGGSAAQKQKISFLENNLEQLTKVHKQLVRDN 853
++L +L +A +K + +S+D KQ + LE + K L+ +
Sbjct: 821 ESLETEMELRSAQIADLQQKLLDAESED-----RPKQCWENIATILEAKCAL-KYLIGEL 874
Query: 854 ADLRCELPKLEKRLRATAERVKALESALKEAKENASRDRKRYQQEVDRIKEAVRSK 909
+ + KLE LR + ++ L E + + S Q E+ R+++ + K
Sbjct: 875 VSSKIHVTKLENSLRQSKASCADMQKMLFEEQNHFSEIETELQAELVRMEQQHQEK 930
Score = 70.1 bits (170), Expect = 9e-12
Identities = 78/372 (20%), Positives = 164/372 (44%), Gaps = 45/372 (12%)
Query: 339 QWKKKYEKEKEKNKILRNTIQWLENELNRWRNGETVPIDEQFDKEKANLEAFTVDKDITL 398
QWK+K +KE + K E +R R E + ++ F K+ + L T ++
Sbjct: 663 QWKQKKDKEVIQLK-----------ERDRKRQYELLKLERNFQKQSSVLRRKT--EEAAA 709
Query: 399 TNDKPATAIGVIGNFTDAERRKC---EEEIAKLYKQLDDKDEEINQQSQLVEKLKTQMLD 455
N + A+ TD + +E IA + + E+ ++ ++ +L+
Sbjct: 710 ANKRLKDALQKQREVTDKRKETQSHGKEGIAARVRNWLGNEIEVMVSTEEAKRHLNDLLE 769
Query: 456 QEELLASTRRDQDNMQAELNRLQAENDASKEEVKEVLQALEELAVNYDQKSQEVEDKTKE 515
++LA QD +Q + + EN K +++ +L E+ + Q + + TK+
Sbjct: 770 DRKILA-----QDVVQLKEKKESRENPPPK--LRKCTFSLSEV---HGQVLESEDCITKQ 819
Query: 516 YELLSDELNQKSATLASIDAELQKLKEMTNHQKKRAAEMMASLLKDLAEIGIAVGNNDVK 575
E L E+ +SA +A + +L L + + K+ E +A++L+ + +G
Sbjct: 820 IESLETEMELRSAQIADLQQKL--LDAESEDRPKQCWENIATILEAKCALKYLIG----- 872
Query: 576 QPEGTGMIDEEFTVARLYISKMKSEVKTMVKRCKQLESTQTESNKKMEENEKELAACQLR 635
E ++++++K+++ ++ C ++ E E E EL A +R
Sbjct: 873 ----------ELVSSKIHVTKLENSLRQSKASCADMQKMLFEEQNHFSEIETELQAELVR 922
Query: 636 ISQ-HEAKIKSLTEYLQNVEQKKRQLEESVDALSEELVQ-LRAQEKVHEMEKEHLNKVQT 693
+ Q H+ K+ L LQ + ++QLE+S ++LV L+ Q++ E +E + Q
Sbjct: 923 MEQQHQEKVLYLVSQLQESQMAEKQLEKSASEKEQQLVSTLQCQDEELEKMREVCEQNQQ 982
Query: 694 ANEVKQAVEQQI 705
+ + ++Q++
Sbjct: 983 LLQENEIIKQKL 994
>gi|38569484 kinesin family member 21A [Homo sapiens]
Length = 1661
Score = 273 bits (698), Expect = 6e-73
Identities = 244/900 (27%), Positives = 423/900 (47%), Gaps = 130/900 (14%)
Query: 6 ECNIKVMCRFRPLNESEVNRGDKYIAKFQ-GEDTVVIAS-KPYAFDRVFQSSTSQEQVYN 63
E +++V R RP E G GE V + K + FD VF + QEQ+Y
Sbjct: 7 ESSVRVAVRIRPQLAKEKIEGCHICTSVTPGEPQVFLGKDKAFTFDYVFDIDSQQEQIYI 66
Query: 64 DCAKKIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHD----PEGMGIIPRIVQDIFNYI 119
C +K+++ EGYN T+FAYGQT +GKT+TM G D E +GII R V+ +F I
Sbjct: 67 QCIEKLIEGCFEGYNATVFAYGQTGAGKTYTM-GTGFDVNIVEEELGIISRAVKHLFKSI 125
Query: 120 -----YSMDENL---EFHIKVSYFEIYLDKIRDLLDVS--------KTNLSVHEDKNRVP 163
++ L +F + + E+Y +++ DL D + K+N+ +HED
Sbjct: 126 EEKKHIAIKNGLPAPDFKVNAQFLELYNEEVLDLFDTTRDIDAKSKKSNIRIHEDSTGGI 185
Query: 164 YVKGCTERFVCSPDEVMDTIDEGKSNRHVAVTNMNEHSSRSHSIFLINVKQE-------- 215
Y G T R V + E+M + G +R A T MN SSRSH+IF I+V Q
Sbjct: 186 YTVGVTTRTVNTESEMMQCLKLGALSRTTASTQMNVQSSRSHAIFTIHVCQTRVCPQIDA 245
Query: 216 NTQTEQK-------------LSGKLYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSALG 262
+ T+ K L+ K + VDLAGSE++ +TGA G E +IN L ALG
Sbjct: 246 DNATDNKIISESAQMNEFETLTAKFHFVDLAGSERLKRTGATGERAKEGISINCGLLALG 305
Query: 263 NVISALAEGS---TYVPYRDSKMTRILQDSLGGNCRTTIVICCSPSSYNESETKSTLLFG 319
NVISAL + S T+VPYRDSK+TR+LQDSLGGN +T ++ C SPS + ET +TL +
Sbjct: 306 NVISALGDKSKRATHVPYRDSKLTRLLQDSLGGNSQTIMIACVSPSDRDFMETLNTLKYA 365
Query: 320 QRAKTIKNTVCVNVELTAEQWKKKYEKEKEKNKILRNTIQWLENELNRWRNGETVPIDEQ 379
RA+ IKN V VN + ++Q LR+ I L+ EL ++ G+ + IDE+
Sbjct: 366 NRARNIKNKVMVNQDRASQQ-----------INALRSEITRLQMELMEYKTGKRI-IDEE 413
Query: 380 FDKEKANLEAFTVDKDITLTNDKPATAIGVIGNFTDAERRKCEEEIA----KLYKQLDDK 435
E N + F + + N+ I + DA R + + ++ + + +
Sbjct: 414 -GVESIN-DMFHENAMLQTENNNLRVRIKAMQETVDALRSRITQLVSDQANHVLARAGEG 471
Query: 436 DEEINQQ----SQLVEKLKTQMLDQEELLASTRRDQDNMQAELNRLQAEND------ASK 485
+EEI+ + +E L+ ++L+ E + + R++ A + +S
Sbjct: 472 NEEISNMIHSYIKEIEDLRAKLLESEAVNENLRKNLTRATARAPYFSGSSTFSPTILSSD 531
Query: 486 EEVKEVL----QALEELAVNYDQKSQEVEDKTKEYELLSDELNQKSAT-LASIDAELQKL 540
+E E++ + LE+L +K + V K + ++ +K + + + E+++
Sbjct: 532 KETIEIIDLAKKDLEKLKRKEKRKKKSVAGKEDNTDTDQEKKEEKGVSERENNELEVEES 591
Query: 541 KEMTNHQKKRAAEMMASLLKDLAEIGIAVGNNDVKQPEGTGMIDEEFTVARLY---ISKM 597
+E+++H+ + E +D+ E + D E Y ++ +
Sbjct: 592 QEVSDHEDEEEEE--------------EEEEDDIDGGESSDESDSESDEKANYQADLANI 637
Query: 598 KSEVKTMVKRCKQLESTQTESNKKMEENEKELAACQLRISQHEAKIKSLTEYLQNVEQKK 657
E+ K +LE++Q K+++ +K Q+E K+ L +++ + ++
Sbjct: 638 TCEIAIKQKLIDELENSQ----KRLQTLKK----------QYEEKLMMLQHKIRDTQLER 683
Query: 658 RQLEESVDALSEELVQLRAQEKVHEMEKEHLNKVQTANEVKQAVEQQIQSH------RET 711
Q+ +++ + V+ ++EK ++ E+ K+Q N+ Q ++ + H +
Sbjct: 684 DQVLQNLGS-----VESYSEEKAKKVRSEYEKKLQAMNKELQRLQAAQKEHARLLKNQSQ 738
Query: 712 HQKQISSLRDEV----EAKAKLITDLQDQNQKMMLEQERLRVEHEKLKATDQEKSRKLHE 767
++KQ+ L+ +V + K +L+ ++++ +K L + R E +LK +++ +L
Sbjct: 739 YEKQLKKLQQDVMEMKKTKVRLMKQMKEEQEKARLTESRRNREIAQLKKDQRKRDHQLRL 798
Query: 768 LTVMQDRREQARQDLKGLEETVAKELQTLHNLRKLFVQDLATRVKKSAEIDSDDTGGSAA 827
L + +E + + EE A Q K V TR S++ + DTG SAA
Sbjct: 799 LEAQKRNQEVVLR--RKTEEVTALRRQVRPMSDK--VAGKVTRKLSSSDAPAQDTGSSAA 854
Score = 32.7 bits (73), Expect = 1.7
Identities = 32/190 (16%), Positives = 82/190 (43%), Gaps = 25/190 (13%)
Query: 444 QLVEKLKTQMLDQEELLASTRRDQDNMQAELNRLQAENDASKEEVKEVLQALEELAVNYD 503
QL+E+ T ++ Q+ ++ NM+A++NRL + + + +++ + E++
Sbjct: 911 QLLERRVTDIIMQKMTIS-------NMEADMNRLLKQREELTKRREKLSKRREKIVKENG 963
Query: 504 QKSQEVEDKTKEYELLSDELNQKSATLASIDAELQKLKEMTNHQKKRAAEMMASLLKDLA 563
+ + V + +E E L+ ++ + +++ A + +++E +
Sbjct: 964 EGDKNVANINEEMESLTANIDYINDSISDCQANIMQMEEAKEEGE--------------- 1008
Query: 564 EIGIAVGNNDVKQPEGTGMIDEEFTVA---RLYISKMKSEVKTMVKRCKQLESTQTESNK 620
+ + N E ++D ++ L ++ ++++K + R KQ E T N+
Sbjct: 1009 TLDVTAVINACTLTEARYLLDHFLSMGINKGLQAAQKEAQIKVLEGRLKQTEITSATQNQ 1068
Query: 621 KMEENEKELA 630
+ KE A
Sbjct: 1069 LLFHMLKEKA 1078
>gi|30794488 kinesin family member 27 [Homo sapiens]
Length = 1401
Score = 269 bits (688), Expect = 8e-72
Identities = 252/937 (26%), Positives = 455/937 (48%), Gaps = 125/937 (13%)
Query: 4 LAECNIKVMCRFRPLNESEVNRGDKYIAKF--QGEDTVVIASKPYAFDRVFQSSTSQEQV 61
+ E +KV R RPL E + + + ++ + + FD VF +++Q++V
Sbjct: 1 MEEIPVKVAVRIRPLLCKEALHNHQVCVRVIPNSQQVIIGRDRVFTFDFVFGKNSTQDEV 60
Query: 62 YNDCAKKIVKDVLEGYNGTIFAYGQTSSGKTHTMEGK--LHDPEGM-GIIPRIVQDIFNY 118
YN C K +V ++EGYN T+FAYGQT SGKT+T+ G EG GIIPR +Q+IF
Sbjct: 61 YNTCIKPLVLSLIEGYNATVFAYGQTGSGKTYTIGGGHIASVVEGQKGIIPRAIQEIFQS 120
Query: 119 IYSMDENLEFHIKVSYFEIYLDKIRDLLDV--SKTNLSVHEDKNRVPYVKGCTERFVCSP 176
I S +++F++KVSY E+Y + +RDLL++ S +L + ED+ + G E V S
Sbjct: 121 I-SEHPSIDFNVKVSYIEVYKEDLRDLLELETSMKDLHIREDEKGNTVIVGAKECHVESA 179
Query: 177 DEVMDTIDEGKSNRHVAVTNMNEHSSRSHSIFLINVKQENTQTEQKLSG----------K 226
EVM ++ G + RH T MNEHSSRSH+IF I++ Q + E G K
Sbjct: 180 GEVMSLLEMGNAARHTGTTQMNEHSSRSHAIFTISICQVHKNMEAAEDGSWYSPRHIVSK 239
Query: 227 LYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAE---GSTYVPYRDSKMT 283
+ VDLAGSE+V+KTG G E+ IN L ALGNVISAL + S+++PYRD+K+T
Sbjct: 240 FHFVDLAGSERVTKTGNTGERFKESIQINSGLLALGNVISALGDPRRKSSHIPYRDAKIT 299
Query: 284 RILQDSLGGNCRTTIVICCSPSSYNESETKSTLLFGQRAKTIKNTVCVNVELTAEQWKKK 343
R+L+DSLGG+ +T ++ C SPSS N E+ ++L + RA+ I+N VN ++ +
Sbjct: 300 RLLKDSLGGSAKTVMITCVSPSSSNFDESLNSLKYANRARNIRNKPTVNFSPESD----R 355
Query: 344 YEKEKEKNKILRNTIQWLE------NELNRWRNGETVPIDEQFDKEKANLEAFTVDKDIT 397
++ + + K+LR +Q + ++NR + +T I +++ A L+ +
Sbjct: 356 IDEMEFEIKLLREALQSQQAGVSQTTQINREGSPDTNRI-HSLEEQVAQLQGECLGYQCC 414
Query: 398 LTNDKPATAIGVIGNFTDAERRKCEEEIAKLYKQLDDKDE-EINQQSQLVEKLKTQMLDQ 456
+ A + + D R L++K + ++ + ++++++ +L
Sbjct: 415 VEE-----AFTFLVDLKDTVR-------------LNEKQQHKLQEWFNMIQEVRKAVLTS 456
Query: 457 EELLASTRRDQDNMQAELNRLQAENDASKEEVKEVLQALEELAVNYDQKSQEVEDKTKEY 516
+ T ++ Q + LQ K E+K+ L V ++QK EV++ +
Sbjct: 457 FRGIGGTASLEEGPQ-HVTVLQL-----KRELKKCQCVLAADEVVFNQKELEVKELKNQV 510
Query: 517 ELLSDELNQKSATLASIDAELQKLKEMTNHQKKRAAEMMASLLKDLAEIGIAVGNNDVKQ 576
+++ E + +L E QK+ + N + ++ L ++L ++ ++V + K+
Sbjct: 511 QMMVQENKGHAVSL----KEAQKVNRLQNEKIIEQQLLVDQLSEELTKLNLSV-TSSAKE 565
Query: 577 PEGTGMIDEEFTVARLYISKMKSEVKTMVKRCKQLESTQTESNKKMEENEKELAACQLRI 636
G G D R Y + + + + +S + ++ M ++ A + R
Sbjct: 566 NCGDGP-DARIPERRPYTVPFDTHLGHYIYIPSRQDSRKVHTSPPMYSLDRIFAGFRTRS 624
Query: 637 SQHEAKIKSLTEYLQNVEQKKRQLEESVDALSEELVQLRAQEKVHEMEKEHLNKVQTANE 696
L ++E++ + L S++ + QEK + + +Q +
Sbjct: 625 QM----------LLGHIEEQDKVLHCQFSDNSDD-EESEGQEKSGTRCRSR-SWIQKPDS 672
Query: 697 VKQAVEQQIQSHRETHQKQISSLRDEVEAKAKLITDLQDQNQKMMLEQERLRVEHEKLKA 756
V VE +S +DE + +DL++++ K+ QE + +KLK
Sbjct: 673 VCSLVE-------------LSDTQDETQK-----SDLENEDLKIDCLQESQELNLQKLKN 714
Query: 757 TDQ---EKSRKLHELTVMQDRREQARQDLKGLEETVAKELQTLHNLRKLFVQDLATRVKK 813
+++ E +K+ ELT+ ++K ++E + KEL N K + + +V K
Sbjct: 715 SERILTEAKQKMRELTI----------NIK-MKEDLIKELIKTGNDAKSVSKQYSLKVTK 763
Query: 814 SAEIDSDDTGGSAAQKQKISFLENNLEQLTKVHKQLVRDNADLRCELPK-LEKRLRATAE 872
++ D A++ K+ +E +QL ++ + + D A ++ +L K K++ A
Sbjct: 764 ---LEHD------AEQAKVELIETQ-KQLQELENKDLSDVA-MKVKLQKEFRKKMDAAKL 812
Query: 873 RVKALESALKEAKENAS---RDRKR---YQQEVDRIK 903
RV+ L+ +++K+ AS ++ KR +Q VD +K
Sbjct: 813 RVQVLQKKQQDSKKLASLSIQNEKRANELEQSVDHMK 849
Score = 60.8 bits (146), Expect = 6e-09
Identities = 104/500 (20%), Positives = 215/500 (43%), Gaps = 78/500 (15%)
Query: 422 EEEIAKLYKQLDDKDEEINQQSQLVEKLKTQMLDQEELLASTRRDQDNMQAELNRLQAEN 481
EE+ L+ Q D ++ + Q EK T+ + + + D++ + + ++
Sbjct: 632 EEQDKVLHCQFSDNSDDEESEGQ--EKSGTRCRSRSWI-----QKPDSVCSLVELSDTQD 684
Query: 482 DASKEEVKEVLQALEELAVNYDQKSQEVE-DKTKEYELLSDELNQKSATLASIDAELQKL 540
+ K +++ E+L ++ Q+SQE+ K K E + E QK +
Sbjct: 685 ETQKSDLEN-----EDLKIDCLQESQELNLQKLKNSERILTEAKQK-------------M 726
Query: 541 KEMTNHQKKRAAEMMASLLKDLAEIGIAVGNNDVKQPEGTGMIDEEFTVARLYISKMKSE 600
+E+T + K M L+K+L + G ND K + +++++ + +
Sbjct: 727 RELTINIK-----MKEDLIKELIKTG-----NDAKS------VSKQYSLKVTKLEHDAEQ 770
Query: 601 VKT-MVKRCKQLESTQTESN-------KKMEENEKELAACQLRIS------QHEAKIKSL 646
K +++ KQL+ + + K +E K++ A +LR+ Q K+ SL
Sbjct: 771 AKVELIETQKQLQELENKDLSDVAMKVKLQKEFRKKMDAAKLRVQVLQKKQQDSKKLASL 830
Query: 647 TEYLQNVEQKKRQLEESVDALSEELVQLRAQEKVHEMEKEHLNKVQTANEVKQAVEQQIQ 706
+ +QN E++ +LE+SVD + + +QL+ + + +++ L+ V ++ K E Q++
Sbjct: 831 S--IQN-EKRANELEQSVDHMKYQKIQLQRKLREENEKRKQLDAVIKRDQQK-IKEIQLK 886
Query: 707 SHRETHQKQISSLRDEVEAKAK-----LITDLQD-QNQKMMLEQERLRVEHEKLKATDQE 760
+ +E K + D K + I LQ QK L++E +V +++ + + E
Sbjct: 887 TGQEEGLKPKAEDLDACNLKRRKGSFGSIDHLQKLDEQKKWLDEEVEKVLNQRQELEELE 946
Query: 761 KSRKLHELTVMQDRREQARQDLKGLEETVAKELQTLH-------NLRKLFVQDLATRVKK 813
K E V ++E Q+ LE + Q L+ L Q+L+ +K
Sbjct: 947 ADLKKREAIV--SKKEALLQEKSHLENKKLRSSQALNTDSLKISTRLNLLEQELS---EK 1001
Query: 814 SAEIDSDDTGGSAAQKQKISFLENNLEQLTKVHKQLVRDNADLRCELPKLEKRLRATAER 873
+ ++ + +++ L+ +QL K + + R P+ E L E
Sbjct: 1002 NVQLQTSTAEEKTKISEQVEVLQKEKDQLQKRRHNVDEKLKNGRVLSPEEEHVLFQLEEG 1061
Query: 874 VKALESALKEAKENASRDRK 893
++ALE+A++ E+ +K
Sbjct: 1062 IEALEAAIEYRNESIQNRQK 1081
Score = 53.1 bits (126), Expect = 1e-06
Identities = 84/401 (20%), Positives = 166/401 (41%), Gaps = 33/401 (8%)
Query: 418 RRKCEEEIAKLYKQLD-------DKDEEINQQSQLVEKLKTQMLDQEELLASTRRDQDNM 470
+RK EE K KQLD K +EI ++ E LK + D + R+
Sbjct: 856 QRKLREENEKR-KQLDAVIKRDQQKIKEIQLKTGQEEGLKPKAEDLDACNLKRRKGSFGS 914
Query: 471 QAELNRLQAENDASKEEVKEVL---QALEELAVNYDQKSQEVEDKTKEYELLSDELNQKS 527
L +L + EEV++VL Q LEEL + ++ V K + S N+K
Sbjct: 915 IDHLQKLDEQKKWLDEEVEKVLNQRQELEELEADLKKREAIVSKKEALLQEKSHLENKKL 974
Query: 528 ATLASIDAELQKLKEMTNHQKKRAAEMMASLLKDLAEIGIAVGNN-DVKQPEGTGM---- 582
+ +++ + K+ N ++ +E L AE + +V Q E +
Sbjct: 975 RSSQALNTDSLKISTRLNLLEQELSEKNVQLQTSTAEEKTKISEQVEVLQKEKDQLQKRR 1034
Query: 583 --IDEEFTVARLYISKMKSEVKTMVKRCKQLESTQTESNKKMEENEKELAACQLRISQHE 640
+DE+ R+ + + + + + + LE+ N+ ++ +K L A +S+ E
Sbjct: 1035 HNVDEKLKNGRVLSPEEEHVLFQLEEGIEALEAAIEYRNESIQNRQKSLRASFHNLSRGE 1094
Query: 641 AKIKSLTEYLQNVEQKKRQLEESVDALSEELVQLRAQEKVHEMEKEHLN-KVQTANEVKQ 699
A + L VE + + ++V LR E+ ++ E + KV + + +
Sbjct: 1095 ANVLEKLACLSPVE-----IRTILFRYFNKVVNLREAERKQQLYNEEMKMKVLERDNMVR 1149
Query: 700 AVEQQIQSHRETHQKQISSLRDEVEAKAKLIT-DLQDQNQKMMLEQ--------ERLRVE 750
+E + + ++++ + E E K +L+ ++Q+ + ++E ++L +
Sbjct: 1150 ELESALDHLKLQCDRRLTLQQKEHEQKMQLLLHHFKEQDGEGIMETFKTYEDKIQQLEKD 1209
Query: 751 HEKLKATDQEKSRKLHELTVMQDRREQARQDLKGLEETVAK 791
K T ++ +KL EL RR+ A + + + V K
Sbjct: 1210 LYFYKKTSRDHKKKLKELVGEAIRRQLAPSEYQEAGDGVLK 1250
Score = 38.9 bits (89), Expect = 0.023
Identities = 45/197 (22%), Positives = 88/197 (44%), Gaps = 26/197 (13%)
Query: 440 NQQSQLVEKLKTQMLDQEELLASTRRDQDNMQAELN------RLQAENDASKEEVKEVLQ 493
N+ L E + Q L EE+ ++DNM EL +LQ + + ++ KE Q
Sbjct: 1118 NKVVNLREAERKQQLYNEEMKMKVL-ERDNMVRELESALDHLKLQCDRRLTLQQ-KEHEQ 1175
Query: 494 ALEELAVNYDQKSQEVEDKTKEYELLSDELNQKSATLASIDAELQKLKEMTNHQKKRAAE 553
++ L ++ K Q+ E + ++ D++ Q ++ +L K+ + KK+ E
Sbjct: 1176 KMQLLLHHF--KEQDGEGIMETFKTYEDKIQQ-------LEKDLYFYKKTSRDHKKKLKE 1226
Query: 554 MMASLLK-DLAEIGIAVGNNDVKQPEGTGMIDEEFTVARLYISKMKSEVKTMVKRCKQLE 612
++ ++ LA + V +PEG GM+ EE K S ++M ++ E
Sbjct: 1227 LVGEAIRRQLAPSEYQEAGDGVLKPEGGGMLSEEL--------KWASRPESMKLSGRERE 1278
Query: 613 STQTESNKKMEENEKEL 629
+ S+ + + N ++L
Sbjct: 1279 MDSSASSLRTQPNPQKL 1295
>gi|13699824 kinesin family member 11 [Homo sapiens]
Length = 1056
Score = 267 bits (683), Expect = 3e-71
Identities = 246/909 (27%), Positives = 411/909 (45%), Gaps = 88/909 (9%)
Query: 8 NIKVMCRFRPLNESEVNRGD----------KYIAKFQGEDTVVIASKPYAFDRVFQSSTS 57
NI+V+ R RP N +E K ++ G + K Y FD VF +ST
Sbjct: 18 NIQVVVRCRPFNLAERKASAHSIVECDPVRKEVSVRTGGLADKSSRKTYTFDMVFGASTK 77
Query: 58 QEQVYNDCAKKIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPEGM--------GIIP 109
Q VY I+ +V+ GYN TIFAYGQT +GKT TMEG+ E GIIP
Sbjct: 78 QIDVYRSVVCPILDEVIMGYNCTIFAYGQTGTGKTFTMEGERSPNEEYTWEEDPLAGIIP 137
Query: 110 RIVQDIFNYIYSMDENLEFHIKVSYFEIYLDKIRDLL----DVSKTNLSVHEDKN-RVPY 164
R + IF + D EF +KVS EIY +++ DLL DVS+ + +N R
Sbjct: 138 RTLHQIFEKL--TDNGTEFSVKVSLLEIYNEELFDLLNPSSDVSERLQMFDDPRNKRGVI 195
Query: 165 VKGCTERFVCSPDEVMDTIDEGKSNRHVAVTNMNEHSSRSHSIFLINVKQENTQTEQK-- 222
+KG E V + DEV +++G + R A T MN +SSRSHS+F + + + T + +
Sbjct: 196 IKGLEEITVHNKDEVYQILEKGAAKRTTAATLMNAYSSRSHSVFSVTIHMKETTIDGEEL 255
Query: 223 -LSGKLYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAEGSTYVPYRDSK 281
GKL LVDLAGSE + ++GA EA NIN+SL LG VI+AL E + +VPYR+SK
Sbjct: 256 VKIGKLNLVDLAGSENIGRSGAVDKRAREAGNINQSLLTLGRVITALVERTPHVPYRESK 315
Query: 282 MTRILQDSLGGNCRTTIVICCSPSSYNESETKSTLLFGQRAKTIKNTVCVNVELTAEQWK 341
+TRILQDSLGG RT+I+ SP+S N ET STL + RAK I N VN +LT +
Sbjct: 316 LTRILQDSLGGRTRTSIIATISPASLNLEETLSTLEYAHRAKNILNKPEVNQKLTKKALI 375
Query: 342 KKYEKEKEKNKILRNTIQWLENELNRWRNGETVPIDEQFDKEKANLEAFTVDKDITLTND 401
K+Y +E E+ L+ +L R V I E+ + + +T+ +
Sbjct: 376 KEYTEEIER----------LKRDLAAAREKNGVYISEENFR--------VMSGKLTVQEE 417
Query: 402 KPATAIGVIGNFTDAERRKCE------EEIAKLYKQLDDKDEEINQQSQLVEKLKTQMLD 455
+ I IG + R E E+ + L +K +E+ + +++ K Q++
Sbjct: 418 QIVELIEKIGAVEEELNRVTELFMDNKNELDQCKSDLQNKTQELETTQKHLQETKLQLVK 477
Query: 456 QEELLASTRRDQDNMQAELNRLQAENDASKEEVKEVLQALEELAVNYDQKSQEVEDKTKE 515
+E + ++ ++ + ++L V+E + + L D+K + +
Sbjct: 478 EEYITSALESTEEKLHDAASKL-------LNTVEETTKDVSGLHSKLDRKKAVDQHNAEA 530
Query: 516 YELLSDELNQKSATLASIDAE-LQKLKEMTNHQKKRAAEMMASLLKDLAEIGIAVGNNDV 574
++ LN + + + K K M K +++S + L I +
Sbjct: 531 QDIFGKNLNSLFNNMEELIKDGSSKQKAMLEVHKTLFGNLLSSSVSALDTITTVALGSLT 590
Query: 575 KQPEGTGMIDEEFTVARLYISKMKSEVKTMVKRCKQLESTQTESNKKMEENEKELAACQL 634
PE + L + +E KT+++ + T S+ +M + ++ ++
Sbjct: 591 SIPENVSTHVSQIFNMILKEQSLAAESKTVLQELINVLKTDLLSSLEMILSPTVVSILKI 650
Query: 635 RISQHEAKIKSLTEYLQNVEQKKRQLEESVDALSEELVQLRAQE--KVHEMEKEHLNKVQ 692
SQ + K+ +E +K++L+ + L L +L+ + E +K+ N +
Sbjct: 651 N-SQLKHIFKTSLTVADKIEDQKKELDGFLSILCNNLHELQENTICSLVESQKQCGNLTE 709
Query: 693 TANEVKQAVEQQ--------------IQSHRETHQKQISSLRDEVEAKAK-LITDLQDQN 737
+KQ Q+ ++ E QK +SS+++ ++ K+K ++ + +
Sbjct: 710 DLKTIKQTHSQELCKLMNLWTERFCALEEKCENIQKPLSSVQENIQQKSKDIVNKMTFHS 769
Query: 738 QKMMLEQE-------RLRVEHEKLKATDQEKSRKLH-ELTVMQDRREQARQDLKGLEETV 789
QK + + E KL + S KL+ L + EQ + L
Sbjct: 770 QKFCADSDGFSQELRNFNQEGTKLVEESVKHSDKLNGNLEKISQETEQRCESLNTRTVYF 829
Query: 790 AKELQTLHNLRKLFVQDLATRVKKSAEIDSDDTGGSAAQKQKISFLENN--LEQLTKVHK 847
+++ + N R+ + +L V + E S D + ++ ++N L+Q+T
Sbjct: 830 SEQWVSSLNEREQELHNLLEVVSQCCEASSSDITEKSDGRKAAHEKQHNIFLDQMTIDED 889
Query: 848 QLVRDNADL 856
+L+ N +L
Sbjct: 890 KLIAQNLEL 898
>gi|83716024 kinesin family member 21B [Homo sapiens]
Length = 1624
Score = 266 bits (680), Expect = 7e-71
Identities = 247/912 (27%), Positives = 412/912 (45%), Gaps = 139/912 (15%)
Query: 1 MADLAECNIKVMCRFRP-LNESEVNRGDKYIAKFQGEDTVVIAS-KPYAFDRVFQSSTSQ 58
MA +C +KV R RP L++ ++ + GE V++ K + +D VF T Q
Sbjct: 1 MAGQGDCCVKVAVRIRPQLSKEKIEGCHICTSVTPGEPQVLLGKDKAFTYDFVFDLDTWQ 60
Query: 59 EQVYNDCAKKIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLH---DPEGMGIIPRIVQDI 115
EQ+Y+ C K+++ EGYN T+ AYGQT +GKT+TM E GIIPR + +
Sbjct: 61 EQIYSTCVSKLIEGCFEGYNATVLAYGQTGAGKTYTMGTGFDMATSEEEQGIIPRAIAHL 120
Query: 116 FNYIYSMDENL--------EFHIKVSYFEIYLDKIRDLLDVSK--------TNLSVHEDK 159
F I EF + + E+Y ++I DL D ++ +N+ +HED
Sbjct: 121 FGGIAERKRRAQEQGVAGPEFKVSAQFLELYNEEILDLFDSTRDPDTRHRRSNIKIHEDA 180
Query: 160 NRVPYVKGCTERFVCSPDEVMDTIDEGKSNRHVAVTNMNEHSSRSHSIFLINVKQENTQT 219
N Y G T R + S +E++ + +G +R A T MN SSRSH+IF I++ Q T
Sbjct: 181 NGGIYTTGVTSRLIHSQEELIQCLKQGALSRTTASTQMNVQSSRSHAIFTIHLCQMRMCT 240
Query: 220 E---------------------QKLSGKLYLVDLAGSEKVSKTGAEGAVLDEAKNINKSL 258
+ + L+ K + VDLAGSE++ +TGA G E +IN L
Sbjct: 241 QPDLVNEAVTGLPDGTPPSSEYETLTAKFHFVDLAGSERLKRTGATGERAKEGISINCGL 300
Query: 259 SALGNVISALAEGS---TYVPYRDSKMTRILQDSLGGNCRTTIVICCSPSSYNESETKST 315
ALGNVISAL + S +VPYRDSK+TR+LQDSLGGN +T ++ C SPS + ET +T
Sbjct: 301 LALGNVISALGDQSKKVVHVPYRDSKLTRLLQDSLGGNSQTIMIACVSPSDRDFMETLNT 360
Query: 316 LLFGQRAKTIKNTVCVNVELTAEQWKKKYEKEKEKNKILRNTIQWLENELNRWRNGETVP 375
L + RA+ IKN V VN + T++Q LR I L+ EL ++ G+ V
Sbjct: 361 LKYANRARNIKNKVVVNQDKTSQQ-----------ISALRAEIARLQMELMEYKAGKRV- 408
Query: 376 IDEQFDKEKANLEAFTVDKDITLTNDKPATAIGVIGNFTDAERRK----CEEEIAKLYKQ 431
I E D + + F + + N + + DA + +E L +
Sbjct: 409 IGE--DGAEGYSDLFRENAMLQKENGALRLRVKAMQEAIDAINNRVTQLMSQEANLLLAK 466
Query: 432 LDDKDEEINQQSQ----LVEKLKTQMLDQEELLASTRRDQDNMQAELNRLQAENDA---- 483
D +E I Q +E+L+T++L+ E + S RR A + A
Sbjct: 467 AGDGNEAIGALIQNYIREIEELRTKLLESEAMNESLRRSLSRASARSPYSLGASPAAPAF 526
Query: 484 ------SKEEVKEVL----QALEELAVNYDQKSQEVEDKTKEYELLSDELNQKSATLASI 533
S E+ EV+ Q LE L K +EV + K E E +K A L
Sbjct: 527 GGSPASSMEDASEVIRRAKQDLERL------KKKEVRQRRKSPE---KEAFKKRAKLQQE 577
Query: 534 DAELQKLKEMTNHQKKRAAEMMASLLKDLAEIGIAVGNNDVKQPEGT--GMID------E 585
++E E +++R D + G D + G+ ++D E
Sbjct: 578 NSEETDENEAEEEEEER----------DESGCEEEEGREDEDEDSGSEESLVDSDSDPEE 627
Query: 586 EFTVARLYISKMKSEVKTMVKRCKQLESTQTESNKKMEENEKELAACQLRISQHEAKIKS 645
+ + ++ + E++ K +LE++Q + E++L Q +I + +
Sbjct: 628 KEVNFQADLADLTCEIEIKQKLIDELENSQRRLQTLKHQYEEKLILLQNKIRDTQLE--- 684
Query: 646 LTEYLQNVEQKKRQLEESVDALSEELVQLRAQEKVHEMEKEHLNKVQTANEVKQAVEQQI 705
LQN+ + EE + + + ++++ EM ++ L K+Q A Q ++
Sbjct: 685 RDRVLQNLSTMECYTEEKANKIKADY-----EKRLREMNRD-LQKLQAA----QKEHARL 734
Query: 706 QSHRETHQKQISSLRDEV----EAKAKLITDLQDQNQKMMLEQERLRVEHEKLKATDQEK 761
++ +++++ L+ EV +AK L+ ++++ Q+ L + + E +LK +E+
Sbjct: 735 LKNQSRYERELKKLQAEVAEMKKAKVALMKQMREEQQRRRLVETKRNREIAQLK---KEQ 791
Query: 762 SRKLHELTVMQDRREQARQDLKGLEETVAKELQTLHNLRKLFVQDLATR-------VKKS 814
R+ ++ ++ ++ Q L+ +E+ L L K + +A R +
Sbjct: 792 RRQEFQIRALESQKRQQEMVLR----RKTQEVSALRRLAKPMSERVAGRAGLKPPMLDSG 847
Query: 815 AEIDSDDTGGSA 826
AE+ + T A
Sbjct: 848 AEVSASTTSSEA 859
Score = 43.9 bits (102), Expect = 7e-04
Identities = 100/505 (19%), Positives = 200/505 (39%), Gaps = 61/505 (12%)
Query: 394 KDITLTNDKPATAIGVIGNFTDAERRKCEEEIAKLYKQLDDKDEEINQQSQLVEKLKTQM 453
+D L D+ + + +T+ + K + D ++ + + ++ ++KL+
Sbjct: 679 RDTQLERDRVLQNLSTMECYTEEKANKIKA----------DYEKRLREMNRDLQKLQAAQ 728
Query: 454 LDQEELLASTRRDQDNMQAELNRLQAENDASKEEVKEVLQALEELAVNYDQKSQEVEDK- 512
+ LL ++Q + EL +LQAE E+K+ AL + Q+ + VE K
Sbjct: 729 KEHARLL----KNQSRYERELKKLQAE----VAEMKKAKVALMKQMREEQQRRRLVETKR 780
Query: 513 TKEYELLSDELNQKSATLASIDAELQKLKEMTNHQKKRAAEMMASLLKDLAEIGIAVGNN 572
+E L E ++ + +++++ ++ +EM +K + + L K ++E G
Sbjct: 781 NREIAQLKKEQRRQEFQIRALESQ-KRQQEMVLRRKTQEVSALRRLAKPMSER--VAGRA 837
Query: 573 DVKQPEGTGMIDEEFTVARLYISKMKSEVKTMVKRCKQLESTQTESNKKMEENEKELAAC 632
+K P M+D A + S SE ++ + + S + N+K+ + A
Sbjct: 838 GLKPP----MLDSG---AEVSASTTSSEAES---GARSVSSIVRQWNRKINHFLGDHPAP 887
Query: 633 QLRISQHEAKIKSLTEYLQNVEQKKRQLEESVDALSEELVQLRAQEKVHEMEKEHLNKVQ 692
+ ++ K Q+ + R +S++ ++V R E + E L K +
Sbjct: 888 TVNGTRPARKKFQKKGASQSFSKAARLKWQSLERRIIDIVMQRMTIVNLEADMERLIKKR 947
Query: 693 TA----NEVKQAVEQQIQSHRETHQKQISSLRDEVEAKAKLITDLQDQNQKMMLEQERLR 748
E + +++Q+ +K + L +E+E A I + D +L
Sbjct: 948 EELFLLQEALRRKRERLQAESPEEEKGLQELAEEIEVLAANIDYINDGITDCQATIVQLE 1007
Query: 749 VEHEKLKATDQE---KSRKLHELTVMQDRREQARQDLKGLEETVAKELQTLHNLRKLFVQ 805
E+L +TD S L E ++ D +A D KGL + KE Q +L
Sbjct: 1008 ETKEELDSTDTSVVISSCSLAEARLLLDNFLKASID-KGL-QVAQKEAQIRLLEGRLRQT 1065
Query: 806 DLATRVKKSAEIDS------------------DDTGGSAAQKQKIS-FLENNLEQLTKVH 846
D+A + +D+ G A+ ++IS F E + Q +
Sbjct: 1066 DMAGSSQNHLLLDALREKAEAHPELQALIYNVQQENGYASTDEEISEFSEGSFSQSFTMK 1125
Query: 847 KQLVRDNADLRCELPKLEKRLRATA 871
D+ + E PKL +++A +
Sbjct: 1126 GSTSHDDFKFKSE-PKLSAQMKAVS 1149
>gi|9910266 kinesin family member 15 [Homo sapiens]
Length = 1388
Score = 262 bits (669), Expect = 1e-69
Identities = 260/933 (27%), Positives = 437/933 (46%), Gaps = 108/933 (11%)
Query: 44 KPYAFDRVFQSSTSQEQVYNDCAKKIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPE 103
K + FD V T+QE V+ AK IV+ + GYNGTIFAYGQT SGKT TM G
Sbjct: 68 KTFTFDHVADVDTTQESVFATVAKSIVESCMSGYNGTIFAYGQTGSGKTFTMMGPSESDN 127
Query: 104 G----MGIIPRIVQDIFNYIYSMDENL----EFHIKVSYFEIYLDKIRDLLDVSKTNLSV 155
G+IPR + +F+ I E F K S+ EIY ++I DLLD + L +
Sbjct: 128 FSHNLRGVIPRSFEYLFSLIDREKEKAGAGKSFLCKCSFIEIYNEQIYDLLDSASAGLYL 187
Query: 156 HEDKNRVPYVKGCTERFVCSPDEVMDTIDEGKSNRHVAVTNMNEHSSRSHSIFLINVK-- 213
E + +V G E+ V S E + G NR VA T+MN SSRSH++F I ++
Sbjct: 188 REHIKKGVFVVGAVEQVVTSAAEAYQVLSGGWRNRRVASTSMNRESSRSHAVFTITIESM 247
Query: 214 QENTQTEQKLSGKLYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAE--- 270
+++ + + L LVDLAGSE+ T AEG L EA NIN+SLS LG VI+AL +
Sbjct: 248 EKSNEIVNIRTSLLNLVDLAGSERQKDTHAEGMRLKEAGNINRSLSCLGQVITALVDVGN 307
Query: 271 -GSTYVPYRDSKMTRILQDSLGGNCRTTIVICCSPSSYNESETKSTLLFGQRAKTIKNTV 329
+V YRDSK+T +L+DSLGGN +T I+ P S ET STL F QRAK IKN
Sbjct: 308 GKQRHVCYRDSKLTFLLRDSLGGNAKTAIIANVHPGSRCFGETLSTLNFAQRAKLIKNKA 367
Query: 330 CVNVEL--TAEQWKKKYEKEKEKNKILRNTIQWLENELNRWRN--------GETVPIDEQ 379
VN + Q + + ++ KE+ L + E+ L R + E + ++
Sbjct: 368 VVNEDTQGNVSQLQAEVKRLKEQLAELASGQTPPESFLTRDKKKTNYMEYFQEAMLFFKK 427
Query: 380 FDKEKANL-EAFTVDKDITLTNDKPATAIGVIGNFTDAERRKCEEEIAKLYKQL------ 432
++EK +L E T +D+TL +K + +I F + + + E KL+K+
Sbjct: 428 SEQEKKSLIEKVTQLEDLTLKKEKFIQSNKMIVKFREDQIIRLE----KLHKESRGGFLP 483
Query: 433 DDKDEEINQQSQLVEKLKTQMLDQEELLASTRRDQDNMQAELNRLQ------------AE 480
+++D +++ ++ L+ Q ++ +A + +++ E RL+ A+
Sbjct: 484 EEQDRLLSELRNEIQTLREQ-IEHHPRVAKYAMENHSLREENRRLRLLEPVKRAQEMDAQ 542
Query: 481 NDASKEEVKEVLQALEELAVN---YDQKSQEVEDKTKEYELLSDELNQKSATLASIDAEL 537
A E+ + +E+ N + K+Q+ E L +L Q L + E
Sbjct: 543 TIAKLEKAFSEISGMEKSDKNQQGFSPKAQKEPCLFANTEKLKAQLLQIQTELNNSKQEY 602
Query: 538 QKLKEMTNHQKKRAAEMMASL------LKDLAEIGIAVGNNDVKQ-----PEGTGMIDEE 586
++ KE+T ++ + SL L++L E A +V Q E +I
Sbjct: 603 EEFKELTRKRQLELESELQSLQKANLNLENLLEATKACKRQEVSQLNKIHAETLKIITTP 662
Query: 587 FTVARLY---ISKMKSEVKTMVKRCKQ----------LESTQTESNKKMEEN-------- 625
+L+ + K+ E+ + Q E E N++ E
Sbjct: 663 TKAYQLHSRPVPKLSPEMGSFGSLYTQNSSILDNDILNEPVPPEMNEQAFEAISEELRTV 722
Query: 626 EKELAACQLRISQHEAKIKSLTEYLQNVEQKKRQLEESVDALSEELVQLRAQE----KVH 681
+++++A Q ++ + E K L +++ +E Q++E SE + + QE +++
Sbjct: 723 QEQMSALQAKLDEEEHKNLKLQQHVDKLEHHSTQMQELFS--SERIDWTKQQEELLSQLN 780
Query: 682 EMEKEHLNKVQTANEVKQAVEQQIQSHRETHQKQISSLRDEVEA----KAKLITDLQDQN 737
+EK+ L + QT N+ ++ ++ + K++SS++ E + + K L +++
Sbjct: 781 VLEKQ-LQETQTKNDFLKSEVHDLRVVLHSADKELSSVKLEYSSFKTNQEKEFNKLSERH 839
Query: 738 QKMMLEQERLRVEHEKL---KATDQEKSRKLHELTVMQ-DRREQARQDLKGLEETVAKEL 793
+ L+ + LR+E+EKL KA Q+ L E+ + D+ + Q+ K ET+ +
Sbjct: 840 MHVQLQLDNLRLENEKLLESKACLQDSYDNLQEIMKFEIDQLSRNLQNFKKENETLKSD- 898
Query: 794 QTLHNLRKLFVQDLATRVKKSAEIDSDDTGGSAAQKQKISFLENNLEQLTKVHKQLVRDN 853
L+NL +L + K S + + D S K+ + LE ++ K + +
Sbjct: 899 --LNNLMELLEAEKERNNKLSLQFEEDKENSS---KEILKVLEAVRQEKQKETAKCEQQM 953
Query: 854 ADLRCELPKLEKRLRATAERVKALESALKEAKE 886
A ++ KLE+ L AT + + +LE + K+
Sbjct: 954 A----KVQKLEESLLATEKVISSLEKSRDSDKK 982
Score = 70.9 bits (172), Expect = 6e-12
Identities = 112/524 (21%), Positives = 221/524 (42%), Gaps = 63/524 (12%)
Query: 417 ERRKCEEEIAKLYKQLDDKDEEINQQSQLVEKLKTQMLDQEELLASTRRD----QDNMQA 472
E R +E+++ L +LD+++ + + Q V+KL+ +EL +S R D Q+ + +
Sbjct: 718 ELRTVQEQMSALQAKLDEEEHKNLKLQQHVDKLEHHSTQMQELFSSERIDWTKQQEELLS 777
Query: 473 ELNRL-------QAENDASKEEVKEVLQAL----EELAVNYDQKSQEVEDKTKEYELLSD 521
+LN L Q +ND K EV ++ L +EL+ + S ++ KE+ LS+
Sbjct: 778 QLNVLEKQLQETQTKNDFLKSEVHDLRVVLHSADKELSSVKLEYSSFKTNQEKEFNKLSE 837
Query: 522 ELNQKSATLASIDAELQKLKEMTNHQKKRAAEMMASLLKDLAEIGIAVGNNDVKQPEGTG 581
L ++ E +KL E + + + ++ ++ + N K+ T
Sbjct: 838 RHMHVQLQLDNLRLENEKLLESKACLQDSYDNLQEIMKFEIDQLSRNLQN--FKKENETL 895
Query: 582 MIDEEFTVARLYISKMKSEVKTMVKRCKQLESTQTESNKKM--------EENEKELAACQ 633
D + L K ++ K Q E + S+K++ +E +KE A C+
Sbjct: 896 KSDLNNLMELLEAEKERNN-----KLSLQFEEDKENSSKEILKVLEAVRQEKQKETAKCE 950
Query: 634 LRISQHEAKIKSLTEYLQNVEQKKRQLEESVDALSEELVQLRAQEKVHEMEKEHLNKVQT 693
Q AK++ L E L E+ LE+S D S++ V ++ E+ K +T
Sbjct: 951 ----QQMAKVQKLEESLLATEKVISSLEKSRD--SDKKVVADLMNQIQELRTSVCEKTET 1004
Query: 694 ANEVKQAVEQQIQSHRETHQKQISSLRDEVEAKA---KLITDLQDQNQKMMLEQERLRVE 750
+ +KQ + ++ + K S+L D E++ K D+ D + + L +E
Sbjct: 1005 IDTLKQEL-------KDINCKYNSALVDREESRVLIKKQEVDILDLKETLRLRILSEDIE 1057
Query: 751 HEKLKATDQEKSRKLHELTVMQDRREQARQDLKGLEETVAKELQTLHNLRKLFVQDLATR 810
+ L + +L+ LT +A + GL ++ +EL ++ +Q+L +
Sbjct: 1058 RDMLCEDLAHATEQLNMLT-------EASKKHSGLLQSAQEELTK----KEALIQELQHK 1106
Query: 811 V-KKSAEIDSDDTGGSAAQKQKISFLENNLEQLTKVHKQLVRDNADLRCELPKLEKRLRA 869
+ +K E++ + +Q +++ E Q + + L KL +
Sbjct: 1107 LNQKKEEVEQKKNEYNFKMRQLEHVMDSAAED-----PQSPKTPPHFQTHLAKLLETQEQ 1161
Query: 870 TAERVKALESALKEAKENASRDRKRYQQEVDRIKEAVRSKNMAR 913
E +A +++L+ + DR+ E+ R+KE +R R
Sbjct: 1162 EIEDGRASKTSLEHLVTKLNEDREVKNAEILRMKEQLREMENLR 1205
Score = 60.5 bits (145), Expect = 8e-09
Identities = 102/494 (20%), Positives = 200/494 (40%), Gaps = 92/494 (18%)
Query: 342 KKYEKEKEKNKI-LRNTIQWLENELNRWRNGETVPIDEQFDKEKANLEAFTVDKDITLTN 400
+ ++KE E K L N ++ LE E R N ++ +E DKE ++ E V + +
Sbjct: 886 QNFKKENETLKSDLNNLMELLEAEKER-NNKLSLQFEE--DKENSSKEILKVLEAVRQEK 942
Query: 401 DKPATAIGVIGNFTDAERRKCEEEIAKLYKQLDDKDEEINQQSQLVEKLKTQMLDQEELL 460
K E KCE+++AK V+KL+ +L E+++
Sbjct: 943 QK--------------ETAKCEQQMAK------------------VQKLEESLLATEKVI 970
Query: 461 ASTRRDQDNMQAELNRLQAENDASKEEVKEVLQALEELAVNYDQKSQEVEDKTKEYELLS 520
+S + +D+ + + L +++E+ ++ E D QE++D +Y
Sbjct: 971 SSLEKSRDSDKKVVADLM-------NQIQELRTSVCEKTETIDTLKQELKDINCKYNSAL 1023
Query: 521 DELNQKSATLASIDAELQKLKEMTNHQKKRAAEMMASLLKDLAEIGIAVGNNDVKQPEGT 580
+ + + + ++ LKE + L +DLA + + +
Sbjct: 1024 VDREESRVLIKKQEVDILDLKETLRLRILSEDIERDMLCEDLAHATEQLNMLTEASKKHS 1083
Query: 581 GMID---EEFTVARLYISKMKSEVKTMVKRCKQLESTQTESNKKMEENEKELAACQL--- 634
G++ EE T I +++ ++ ++ +++E + E N KM + E + +
Sbjct: 1084 GLLQSAQEELTKKEALIQELQHKLN---QKKEEVEQKKNEYNFKMRQLEHVMDSAAEDPQ 1140
Query: 635 ------RISQHEAKIKSLTEY-LQNVEQKKRQLEESVDALSEELVQ-----LRAQEKVHE 682
H AK+ E +++ K LE V L+E+ LR +E++ E
Sbjct: 1141 SPKTPPHFQTHLAKLLETQEQEIEDGRASKTSLEHLVTKLNEDREVKNAEILRMKEQLRE 1200
Query: 683 MEKEHLNKVQTA----------NEVKQAVEQQIQSHRETHQ---KQISSLRDEVEAKAKL 729
ME L Q +++K+ E Q+H + Q +Q S+++ + AK+K+
Sbjct: 1201 MENLRLESQQLIEKNWLLQGQLDDIKRQKENSDQNHPDNQQLKNEQEESIKERL-AKSKI 1259
Query: 730 ITDLQDQNQKMMLEQERL-RVEHEKLKATD-------------QEKSRKLHELTVMQDRR 775
+ ++ + Q L E E L+ TD QEK + +L M + R
Sbjct: 1260 VEEMLKMKADLEEVQSALYNKEMECLRMTDEVERTQTLESKAFQEKEQLRSKLEEMYEER 1319
Query: 776 EQARQDLKGLEETV 789
E+ Q+++ L + V
Sbjct: 1320 ERTSQEMEMLRKQV 1333
Score = 57.0 bits (136), Expect = 8e-08
Identities = 113/542 (20%), Positives = 208/542 (38%), Gaps = 96/542 (17%)
Query: 302 CSPSSYNESETKSTLLFGQRAKTIKNTVCVNVELTAE--QWKKKYEKEKEKNKILRNTIQ 359
C SY+ + Q ++ ++N N L ++ + E EKE+N L ++Q
Sbjct: 862 CLQDSYDNLQEIMKFEIDQLSRNLQNFKKENETLKSDLNNLMELLEAEKERNNKL--SLQ 919
Query: 360 WLENELN-------------RWRNGETVPIDEQFDK----EKANLEAFTVDKDITLTNDK 402
+ E++ N + + ET ++Q K E++ L V + + D
Sbjct: 920 FEEDKENSSKEILKVLEAVRQEKQKETAKCEQQMAKVQKLEESLLATEKVISSLEKSRDS 979
Query: 403 PATAIGVIGNFTDAERRK-CE--EEIAKLYKQLDDKDEEIN-------QQSQLVEKLKTQ 452
+ + N R CE E I L ++L D + + N + L++K +
Sbjct: 980 DKKVVADLMNQIQELRTSVCEKTETIDTLKQELKDINCKYNSALVDREESRVLIKKQEVD 1039
Query: 453 MLDQEELLA------STRRDQ--DNMQAELNRLQAENDASK----------EEVKEVLQA 494
+LD +E L RD +++ +L +ASK EE+ +
Sbjct: 1040 ILDLKETLRLRILSEDIERDMLCEDLAHATEQLNMLTEASKKHSGLLQSAQEELTKKEAL 1099
Query: 495 LEELAVNYDQKSQEVEDKTKEYELLSDELN----------QKSATLASIDAELQKLKEMT 544
++EL +QK +EVE K EY +L Q T L KL E
Sbjct: 1100 IQELQHKLNQKKEEVEQKKNEYNFKMRQLEHVMDSAAEDPQSPKTPPHFQTHLAKLLETQ 1159
Query: 545 NHQKKRAAEMMASLLKDLAEIGIAVGNNDVKQPEGTGMIDEEFTVARLYISKMKSEVKTM 604
+ + SL + ++ + +VK E M ++ + L + + K
Sbjct: 1160 EQEIEDGRASKTSLEHLVTKLN---EDREVKNAEILRMKEQLREMENLRLESQQLIEKNW 1216
Query: 605 --------VKRCKQLESTQTESNKKMEENEKELAACQLRISQHEAKIKSLTEYLQNVEQK 656
+KR K+ N++++ ++E I + AK K + E L +
Sbjct: 1217 LLQGQLDDIKRQKENSDQNHPDNQQLKNEQEE------SIKERLAKSKIVEEML----KM 1266
Query: 657 KRQLEESVDAL-SEELVQLRAQEKVHEMEKEHLNKVQTANEVKQAVEQQIQSHRETHQ-- 713
K LEE AL ++E+ LR ++V + Q +++ +E+ + T Q
Sbjct: 1267 KADLEEVQSALYNKEMECLRMTDEVERTQTLESKAFQEKEQLRSKLEEMYEERERTSQEM 1326
Query: 714 ----KQISSLRDE---------VEAKAKLITDLQDQNQKMMLEQERLRVEHEKLKATDQE 760
KQ+ L +E + K + + L+ +N ++ E E+LR E+ LK +
Sbjct: 1327 EMLRKQVECLAEENGKLVGHQNLHQKIQYVVRLKKENVRLAEETEKLRAENVFLKEKKRS 1386
Query: 761 KS 762
+S
Sbjct: 1387 ES 1388
>gi|41393559 kinesin family member 1B isoform alpha [Homo sapiens]
Length = 1153
Score = 254 bits (648), Expect = 4e-67
Identities = 155/379 (40%), Positives = 221/379 (58%), Gaps = 28/379 (7%)
Query: 4 LAECNIKVMCRFRPLNESEVNRGDKYIAKFQGEDTVVI-------ASKPYAFDRVFQSST 56
++ ++KV R RP N E ++ K I + QG T +I A K ++FD + S T
Sbjct: 1 MSGASVKVAVRVRPFNSRETSKESKCIIQMQGNSTSIINPKNPKEAPKSFSFDYSYWSHT 60
Query: 57 S--------QEQVYNDCAKKIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPEGMGII 108
S Q +VYND K+++ EGYN IFAYGQT +GK++TM GK + + GII
Sbjct: 61 SPEDPCFASQNRVYNDIGKEMLLHAFEGYNVCIFAYGQTGAGKSYTMMGKQEESQA-GII 119
Query: 109 PRIVQDIFNYIY-SMDENLEFHIKVSYFEIYLDKIRDLLDV-SKTNLSVHEDKNRVPYVK 166
P++ +++F I + +E + + ++VSY EIY +++RDLL+ +K NL V E PYV+
Sbjct: 120 PQLCEELFEKINDNCNEEMSYSVEVSYMEIYCERVRDLLNPKNKGNLRVREHPLLGPYVE 179
Query: 167 GCTERFVCSPDEVMDTIDEGKSNRHVAVTNMNEHSSRSHSIFLINVKQENTQTEQKLS-- 224
++ V S ++ D +D G R VA TNMNE SSRSH++F I Q+ E LS
Sbjct: 180 DLSKLAVTSYTDIADLMDAGNKARTVAATNMNETSSRSHAVFTIVFTQKKHDNETNLSTE 239
Query: 225 --GKLYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAEGST------YVP 276
K+ LVDLAGSE+ TGA+G L E NINKSL+ LG VISALAE S ++P
Sbjct: 240 KVSKISLVDLAGSERADSTGAKGTRLKEGANINKSLTTLGKVISALAEVSKKKKKTDFIP 299
Query: 277 YRDSKMTRILQDSLGGNCRTTIVICCSPSSYNESETKSTLLFGQRAKTIKNTVCVNVELT 336
YRDS +T +L+++LGGN RT +V SP+ N ET STL + RAK IK +N +
Sbjct: 300 YRDSVLTWLLRENLGGNSRTAMVAALSPADINYDETLSTLRYADRAKQIKCNAVINEDPN 359
Query: 337 AEQWKKKYEKEKEKNKILR 355
A+ ++ E+ +LR
Sbjct: 360 AKLVRELKEEVTRLKDLLR 378
>gi|41393563 kinesin family member 1B isoform b [Homo sapiens]
Length = 1770
Score = 254 bits (648), Expect = 4e-67
Identities = 155/379 (40%), Positives = 221/379 (58%), Gaps = 28/379 (7%)
Query: 4 LAECNIKVMCRFRPLNESEVNRGDKYIAKFQGEDTVVI-------ASKPYAFDRVFQSST 56
++ ++KV R RP N E ++ K I + QG T +I A K ++FD + S T
Sbjct: 1 MSGASVKVAVRVRPFNSRETSKESKCIIQMQGNSTSIINPKNPKEAPKSFSFDYSYWSHT 60
Query: 57 S--------QEQVYNDCAKKIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPEGMGII 108
S Q +VYND K+++ EGYN IFAYGQT +GK++TM GK + + GII
Sbjct: 61 SPEDPCFASQNRVYNDIGKEMLLHAFEGYNVCIFAYGQTGAGKSYTMMGKQEESQA-GII 119
Query: 109 PRIVQDIFNYIY-SMDENLEFHIKVSYFEIYLDKIRDLLDV-SKTNLSVHEDKNRVPYVK 166
P++ +++F I + +E + + ++VSY EIY +++RDLL+ +K NL V E PYV+
Sbjct: 120 PQLCEELFEKINDNCNEEMSYSVEVSYMEIYCERVRDLLNPKNKGNLRVREHPLLGPYVE 179
Query: 167 GCTERFVCSPDEVMDTIDEGKSNRHVAVTNMNEHSSRSHSIFLINVKQENTQTEQKLS-- 224
++ V S ++ D +D G R VA TNMNE SSRSH++F I Q+ E LS
Sbjct: 180 DLSKLAVTSYTDIADLMDAGNKARTVAATNMNETSSRSHAVFTIVFTQKKHDNETNLSTE 239
Query: 225 --GKLYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAEGST------YVP 276
K+ LVDLAGSE+ TGA+G L E NINKSL+ LG VISALAE S ++P
Sbjct: 240 KVSKISLVDLAGSERADSTGAKGTRLKEGANINKSLTTLGKVISALAEVSKKKKKTDFIP 299
Query: 277 YRDSKMTRILQDSLGGNCRTTIVICCSPSSYNESETKSTLLFGQRAKTIKNTVCVNVELT 336
YRDS +T +L+++LGGN RT +V SP+ N ET STL + RAK IK +N +
Sbjct: 300 YRDSVLTWLLRENLGGNSRTAMVAALSPADINYDETLSTLRYADRAKQIKCNAVINEDPN 359
Query: 337 AEQWKKKYEKEKEKNKILR 355
A+ ++ E+ +LR
Sbjct: 360 AKLVRELKEEVTRLKDLLR 378
>gi|170784809 kinesin family member 17 isoform b [Homo sapiens]
Length = 1028
Score = 253 bits (646), Expect = 6e-67
Identities = 262/943 (27%), Positives = 423/943 (44%), Gaps = 123/943 (13%)
Query: 9 IKVMCRFRPLNESEVNRGDKYIAK---------FQGEDTVVIASKPYAFDRVFQSSTSQE 59
+KV+ R RP+N+ E + + Q K + FD + E
Sbjct: 6 VKVVVRCRPMNQRERELRCQPVVTVDCARAQCCIQNPGAADEPPKQFTFDGAYHVDHVTE 65
Query: 60 QVYNDCAKKIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPEGMGIIPRIVQDIFNYI 119
Q+YN+ A +V+ V EGYNGTIFAYGQT SGK+ TM+G P GIIPR + +F +
Sbjct: 66 QIYNEIAYPLVEGVTEGYNGTIFAYGQTGSGKSFTMQGLPDPPSQRGIIPRAFEHVFESV 125
Query: 120 YSMDENLEFHIKVSYFEIYLDKIRDLLDV-SKTNLSVHEDKNRVPYVKGCTERFVCSPDE 178
EN +F ++ SY EIY + +RDLL +K L + E + YVKG + V S +
Sbjct: 126 -QCAENTKFLVRASYLEIYNEDVRDLLGADTKQKLELKEHPEKGVYVKGLSMHTVHSVAQ 184
Query: 179 VMDTIDEGKSNRHVAVTNMNEHSSRSHSIFLINVKQENTQTEQK---LSGKLYLVDLAGS 235
++ G NR V T MN+ SSRSHSIF I+++ K +GKL LVDLAGS
Sbjct: 185 CEHIMETGWKNRSVGYTLMNKDSSRSHSIFTISIEMSAVDERGKDHLRAGKLNLVDLAGS 244
Query: 236 EKVSKTGAEGAVLDEAKNINKSLSALGNVISALAEG-STYVPYRDSKMTRILQDSLGGNC 294
E+ SKTGA G L EA IN SLSALGNVISAL +G +VPYRDSK+TR+LQDSLGGN
Sbjct: 245 ERQSKTGATGERLKEATKINLSLSALGNVISALVDGRCKHVPYRDSKLTRLLQDSLGGNT 304
Query: 295 RTTIVICCSPSSYNESETKSTLLFGQRAKTIKNTVCVNVELTAEQWKKKYEKEKEKNKIL 354
+T +V C SP+ N ET STL + RAK I+N +N E + ++Y++E +K K +
Sbjct: 305 KTLMVACLSPADNNYDETLSTLRYANRAKNIRNKPRIN-EDPKDALLREYQEEIKKLKAI 363
Query: 355 RNTIQWLENELNRWRNGETVPIDEQFDKEKANLEAFTVDKDITLTNDKPATAIGVIGNFT 414
T Q + L+ + + P Q +++ +P VI +
Sbjct: 364 L-TQQMSPSSLSALLSRQVPPDPVQVEEKLL---------------PQP-----VIQHDV 402
Query: 415 DAERRKCEEEIAKLYKQLD-DKDEEINQQSQLVEKLKTQMLDQEELLASTRRDQDNMQAE 473
+AE++ EE + +L D E +++L E + T M + ++ ST ++N++ E
Sbjct: 403 EAEKQLIREEYEERLARLKADYKAEQESRARLEEDI-TAMRNSYDVRLSTL--EENLRKE 459
Query: 474 LNRLQAENDASKEEVKEVLQALEELAVNYDQKSQEVEDKTKEYELLSDELNQKSATLASI 533
+ K EV + E A S E + ++ ++ + TL S
Sbjct: 460 TEAVLQVGVLYKAEV----MSRAEFA-----SSAEYPPAFQYETVVKPKVFSTTDTLPSD 510
Query: 534 DAELQKLKEMTNHQKKRAAEMMASLLK-DLAEIGIAVGNNDVKQPEGTGMID-----EEF 587
D K + + A L K + ++ I++G+++ E T + + EE
Sbjct: 511 DV-----------SKTQVSSRFAELPKVEPSKSEISLGSSESSSLEETSVSEAFPGPEEP 559
Query: 588 TVARLYISKMKSEVKTMVKRCKQLEST---QTESNKKMEENEKE-----LAACQLRISQH 639
+ + + +S + + C E+ E N +E +E L Q ++
Sbjct: 560 SNVEVSMPTEESRSRYFLDECLGQEAAGHLLGEQNYLPQEEPQEVPLQGLLGLQDPFAEV 619
Query: 640 EAKIKSLTEYLQNVEQKKRQLEE---SVDALSEELVQLRAQEKVHEMEKEHLNKVQTANE 696
EAK+ L+ + + + + + V A ++ L A+ E E + E
Sbjct: 620 EAKLARLSSTVARTDAPQADVPKVPVQVPAPTDLLEPSDARP-----EAEAADDFPPRPE 674
Query: 697 VKQAVEQQIQSHRETHQKQISSLRDEVEAKAKLITDLQDQNQKMMLEQERLRVE-----H 751
V A E ++ R + E +A L+ + +++E + +E
Sbjct: 675 VDLASEVALEVVRTAE----PGVWLEAQAPVALVAQPEPLPATAGVKRESVGMEVAVLTD 730
Query: 752 EKLKATDQEKSRKLHELTVMQDRREQARQDLKGLEETVAKELQTLHNLRKLFVQDLATRV 811
+ L DQ++ + R + Q + G E+ K+L+ H RK + + ++
Sbjct: 731 DPLPVVDQQQ---------VLARLQLLEQQVVGGEQAKNKDLKEKHKRRKRYADERRKQL 781
Query: 812 KKSAEIDSDDTGGSAAQKQKISFLENNLEQLTKVHKQLVRDNADLRCELPKLEKRLRATA 871
+ + +D+G S E VR + L L K++++LRA
Sbjct: 782 VAALQNSDEDSGDWVLLNVYDSIQEE------------VRAKSKL---LEKMQRKLRAAE 826
Query: 872 ERVKALESALKEAK-------ENASRDRKRYQQEVDRIKEAVR 907
+K L+S + K RD QQ +++++ +R
Sbjct: 827 VEIKDLQSEFQLEKIDYLATIRRQERDSMLLQQLLEQVQPLIR 869
>gi|170784807 kinesin family member 17 isoform a [Homo sapiens]
Length = 1029
Score = 253 bits (646), Expect = 6e-67
Identities = 262/943 (27%), Positives = 423/943 (44%), Gaps = 123/943 (13%)
Query: 9 IKVMCRFRPLNESEVNRGDKYIAK---------FQGEDTVVIASKPYAFDRVFQSSTSQE 59
+KV+ R RP+N+ E + + Q K + FD + E
Sbjct: 6 VKVVVRCRPMNQRERELRCQPVVTVDCARAQCCIQNPGAADEPPKQFTFDGAYHVDHVTE 65
Query: 60 QVYNDCAKKIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPEGMGIIPRIVQDIFNYI 119
Q+YN+ A +V+ V EGYNGTIFAYGQT SGK+ TM+G P GIIPR + +F +
Sbjct: 66 QIYNEIAYPLVEGVTEGYNGTIFAYGQTGSGKSFTMQGLPDPPSQRGIIPRAFEHVFESV 125
Query: 120 YSMDENLEFHIKVSYFEIYLDKIRDLLDV-SKTNLSVHEDKNRVPYVKGCTERFVCSPDE 178
EN +F ++ SY EIY + +RDLL +K L + E + YVKG + V S +
Sbjct: 126 -QCAENTKFLVRASYLEIYNEDVRDLLGADTKQKLELKEHPEKGVYVKGLSMHTVHSVAQ 184
Query: 179 VMDTIDEGKSNRHVAVTNMNEHSSRSHSIFLINVKQENTQTEQK---LSGKLYLVDLAGS 235
++ G NR V T MN+ SSRSHSIF I+++ K +GKL LVDLAGS
Sbjct: 185 CEHIMETGWKNRSVGYTLMNKDSSRSHSIFTISIEMSAVDERGKDHLRAGKLNLVDLAGS 244
Query: 236 EKVSKTGAEGAVLDEAKNINKSLSALGNVISALAEG-STYVPYRDSKMTRILQDSLGGNC 294
E+ SKTGA G L EA IN SLSALGNVISAL +G +VPYRDSK+TR+LQDSLGGN
Sbjct: 245 ERQSKTGATGERLKEATKINLSLSALGNVISALVDGRCKHVPYRDSKLTRLLQDSLGGNT 304
Query: 295 RTTIVICCSPSSYNESETKSTLLFGQRAKTIKNTVCVNVELTAEQWKKKYEKEKEKNKIL 354
+T +V C SP+ N ET STL + RAK I+N +N E + ++Y++E +K K +
Sbjct: 305 KTLMVACLSPADNNYDETLSTLRYANRAKNIRNKPRIN-EDPKDALLREYQEEIKKLKAI 363
Query: 355 RNTIQWLENELNRWRNGETVPIDEQFDKEKANLEAFTVDKDITLTNDKPATAIGVIGNFT 414
T Q + L+ + + P Q +++ +P VI +
Sbjct: 364 L-TQQMSPSSLSALLSRQVPPDPVQVEEKLL---------------PQP-----VIQHDV 402
Query: 415 DAERRKCEEEIAKLYKQLD-DKDEEINQQSQLVEKLKTQMLDQEELLASTRRDQDNMQAE 473
+AE++ EE + +L D E +++L E + T M + ++ ST ++N++ E
Sbjct: 403 EAEKQLIREEYEERLARLKADYKAEQESRARLEEDI-TAMRNSYDVRLSTL--EENLRKE 459
Query: 474 LNRLQAENDASKEEVKEVLQALEELAVNYDQKSQEVEDKTKEYELLSDELNQKSATLASI 533
+ K EV + E A S E + ++ ++ + TL S
Sbjct: 460 TEAVLQVGVLYKAEV----MSRAEFA-----SSAEYPPAFQYETVVKPKVFSTTDTLPSD 510
Query: 534 DAELQKLKEMTNHQKKRAAEMMASLLK-DLAEIGIAVGNNDVKQPEGTGMID-----EEF 587
D K + + A L K + ++ I++G+++ E T + + EE
Sbjct: 511 DV-----------SKTQVSSRFAELPKVEPSKSEISLGSSESSSLEETSVSEAFPGPEEP 559
Query: 588 TVARLYISKMKSEVKTMVKRCKQLEST---QTESNKKMEENEKE-----LAACQLRISQH 639
+ + + +S + + C E+ E N +E +E L Q ++
Sbjct: 560 SNVEVSMPTEESRSRYFLDECLGQEAAGHLLGEQNYLPQEEPQEVPLQGLLGLQDPFAEV 619
Query: 640 EAKIKSLTEYLQNVEQKKRQLEE---SVDALSEELVQLRAQEKVHEMEKEHLNKVQTANE 696
EAK+ L+ + + + + + V A ++ L A+ E E + E
Sbjct: 620 EAKLARLSSTVARTDAPQADVPKVPVQVPAPTDLLEPSDARP-----EAEAADDFPPRPE 674
Query: 697 VKQAVEQQIQSHRETHQKQISSLRDEVEAKAKLITDLQDQNQKMMLEQERLRVE-----H 751
V A E ++ R + E +A L+ + +++E + +E
Sbjct: 675 VDLASEVALEVVRTAE----PGVWLEAQAPVALVAQPEPLPATAGVKRESVGMEVAVLTD 730
Query: 752 EKLKATDQEKSRKLHELTVMQDRREQARQDLKGLEETVAKELQTLHNLRKLFVQDLATRV 811
+ L DQ++ + R + Q + G E+ K+L+ H RK + + ++
Sbjct: 731 DPLPVVDQQQ---------VLARLQLLEQQVVGGEQAKNKDLKEKHKRRKRYADERRKQL 781
Query: 812 KKSAEIDSDDTGGSAAQKQKISFLENNLEQLTKVHKQLVRDNADLRCELPKLEKRLRATA 871
+ + +D+G S E VR + L L K++++LRA
Sbjct: 782 VAALQNSDEDSGDWVLLNVYDSIQEE------------VRAKSKL---LEKMQRKLRAAE 826
Query: 872 ERVKALESALKEAK-------ENASRDRKRYQQEVDRIKEAVR 907
+K L+S + K RD QQ +++++ +R
Sbjct: 827 VEIKDLQSEFQLEKIDYLATIRRQERDSMLLQQLLEQVQPLIR 869
>gi|19924175 axonal transport of synaptic vesicles [Homo sapiens]
Length = 1690
Score = 249 bits (636), Expect = 9e-66
Identities = 154/400 (38%), Positives = 228/400 (57%), Gaps = 52/400 (13%)
Query: 4 LAECNIKVMCRFRPLNESEVNRGDKYIAKFQGEDTVVI-------ASKPYAFDRVFQSST 56
+A ++KV R RP N E++R K I + G T ++ K ++FD + S T
Sbjct: 1 MAGASVKVAVRVRPFNSREMSRDSKCIIQMSGSTTTIVNPKQPKETPKSFSFDYSYWSHT 60
Query: 57 S--------QEQVYNDCAKKIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPEGMGII 108
S Q+QVY D +++++ EGYN IFAYGQT +GK++TM GK + + GII
Sbjct: 61 SPEDINYASQKQVYRDIGEEMLQHAFEGYNVCIFAYGQTGAGKSYTMMGK-QEKDQQGII 119
Query: 109 PRIVQDIFNYIY-SMDENLEFHIKVSYFEIYLDKIRDLLDV-SKTNLSVHEDKNRVPYVK 166
P++ +D+F+ I + ++N+ + ++VSY EIY +++RDLL+ +K NL V E PYV+
Sbjct: 120 PQLCEDLFSRINDTTNDNMSYSVEVSYMEIYCERVRDLLNPKNKGNLRVREHPLLGPYVE 179
Query: 167 GCTERFVCSPDEVMDTIDEGKSNRHVAVTNMNEHSSRSHSIFLINVKQENTQTEQKLS-- 224
++ V S +++ D +D G R VA TNMNE SSRSH++F I Q+ E ++
Sbjct: 180 DLSKLAVTSYNDIQDLMDSGNKARTVAATNMNETSSRSHAVFNIIFTQKRHDAETNITTE 239
Query: 225 --GKLYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAEGST--------- 273
K+ LVDLAGSE+ TGA+G L E NINKSL+ LG VISALAE +
Sbjct: 240 KVSKISLVDLAGSERADSTGAKGTRLKEGANINKSLTTLGKVISALAEMDSGPNKNKKKK 299
Query: 274 ---YVPYRDSKMTRILQDSLGGNCRTTIVICCSPSSYNESETKSTLLFGQRAKTIKNTVC 330
++PYRDS +T +L+++LGGN RT +V SP+ N ET STL + RAK I+
Sbjct: 300 KTDFIPYRDSVLTWLLRENLGGNSRTAMVAALSPADINYDETLSTLRYADRAKQIRCNAV 359
Query: 331 VNVELTAEQWKKKYEKEKEKNKILRNTIQWLENELNRWRN 370
+N E NK++R L++E+ R R+
Sbjct: 360 IN--------------EDPNNKLIRE----LKDEVTRLRD 381
>gi|41327691 kinesin-like motor protein C20orf23 [Homo sapiens]
Length = 1317
Score = 247 bits (631), Expect = 3e-65
Identities = 272/1115 (24%), Positives = 494/1115 (44%), Gaps = 201/1115 (18%)
Query: 8 NIKVMCRFRPLNESEVNRGDKYIAKFQGEDTVVI---------------ASKPYAFDRVF 52
++KV R RP+N E + K+I + + T + +K + +D F
Sbjct: 3 SVKVAVRVRPMNRREKDLEAKFIIQMEKSKTTITNLKIPEGGTGDSGRERTKTFTYDFSF 62
Query: 53 QSS-------TSQEQVYNDCAKKIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPEGM 105
S+ SQE V+ +VK EGYN +FAYGQT SGK++TM G D
Sbjct: 63 YSADTKSPDYVSQEMVFKTLGTDVVKSAFEGYNACVFAYGQTGSGKSYTMMGNSGDS--- 119
Query: 106 GIIPRIVQDIFNYIYSMD--ENLEFHIKVSYFEIYLDKIRDLL--DVSKT-NLSVHEDKN 160
G+IPRI + +F+ I + F +VSY EIY +++RDLL SKT NL V E
Sbjct: 120 GLIPRICEGLFSRINETTRWDEASFRTEVSYLEIYNERVRDLLRRKSSKTFNLRVREHPK 179
Query: 161 RVPYVKGCTERFVCSPDEVMDTIDEGKSNRHVAVTNMNEHSSRSHSIFLINVKQENTQTE 220
PYV+ ++ V + +V + +D G NR A T MN+ SSRSH+IF I Q +E
Sbjct: 180 EGPYVEDLSKHLVQNYGDVEELMDAGNINRTTAATGMNDVSSRSHAIFTIKFTQAKFDSE 239
Query: 221 QKLS--GKLYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAEGS------ 272
K++LVDLAGSE+ TGA G L E NINKSL LGNVISALA+ S
Sbjct: 240 MPCETVSKIHLVDLAGSERADATGATGVRLKEGGNINKSLVTLGNVISALADLSQDAANT 299
Query: 273 ------TYVPYRDSKMTRILQDSLGGNCRTTIVICCSPSSYNESETKSTLLFGQRAKTIK 326
+VPYRDS +T +L+DSLGGN +T ++ SP+ N ET STL + RAK I
Sbjct: 300 LAKKKQVFVPYRDSVLTWLLKDSLGGNSKTIMIATISPADVNYGETLSTLRYANRAKNII 359
Query: 327 NTVCVNV--------ELTAEQWKKK-------------------YEKEKEKN--KILRNT 357
N +N EL AE + K E++ ++N ++ T
Sbjct: 360 NKPTINEDANVKLIRELRAEIARLKTLLAQGNQIALLDSPTALSMEEKLQQNEARVQELT 419
Query: 358 IQWLENELNRWRNGETVPIDEQFDKEKANLEAFTVDKDI--TLTNDKPATAIGVI----- 410
+W N+W + + ++ K + +D ++ + D + G+I
Sbjct: 420 KEW----TNKWNETQNILKEQTLALRKEGI-GVVLDSELPHLIGIDDDLLSTGIILYHLK 474
Query: 411 --GNFTDAERRKCEEEIAKLYKQLDDKD---EEINQQSQLVEKLKTQ-MLDQEELLASTR 464
+ + E++I L+ + E I L+ +Q ++ +++ +T
Sbjct: 475 EGQTYVGRDDASTEQDIVLHGLDLESEHCIFENIGGTVTLIPLSGSQCSVNGVQIVEATH 534
Query: 465 RDQDNM----QAELNRLQAENDASK--EEVKEVLQALEELAVNYDQKSQEVEDKTKEYEL 518
+Q + + + R +A+K E+ K L + L++ KS+E Y
Sbjct: 535 LNQGAVILLGRTNMFRFNHPKEAAKLREKRKSGLLSSFSLSMTDLSKSRENLSAVMLYNP 594
Query: 519 LSDELNQKSATLASIDAELQKLKEMTNHQKKRAAEM------MASLLKDLAEIGIAVGNN 572
+ Q+ L ++++ + ++EM QK AE+ + + K+ + + +
Sbjct: 595 GLEFERQQREELEKLESKRKLIEEMEEKQKSDKAELERMQQEVETQRKETEIVQLQIRKQ 654
Query: 573 DVKQPEGTGMID----------EEFTVARL------YISKMKSEVKTMVK------RCKQ 610
+ + I+ E+F RL + K + E +T ++ R K+
Sbjct: 655 EESLKRRSFHIENKLKDLLAEKEKFEEERLREQQEIELQKKRQEEETFLRVQEELQRLKE 714
Query: 611 LESTQ--------TESNKKMEENEKELAACQLRISQHEAKIKSLTEYLQNVEQKKRQLEE 662
L + + E ++ +E +++ A +L + E + K + ++E++ R+ +E
Sbjct: 715 LNNNEKAEKFQIFQELDQLQKEKDEQYAKLELEKKRLEEQEKEQVMLVAHLEEQLREKQE 774
Query: 663 SVDALSEELVQLRAQEKVHEME--KEHLNKVQTA--------NEVKQAVEQQIQSHRETH 712
+ L VQ +EK ++E +E L +V+ A E+++A + + R
Sbjct: 775 MIQLLRRGEVQWVEEEK-RDLEGIRESLLRVKEARAGGDEDGEELEKAQLRFFEFKRRQL 833
Query: 713 QKQISSLRDEVEAKAKLITDLQDQNQKMML------EQERLRVEH--------------E 752
K ++ +D V+ K L ++Q++ + + ++ RL +H E
Sbjct: 834 VKLVNLEKDLVQQKDILKKEVQEEQEILECLKCEHDKESRLLEKHDESVTDVTEVPQDFE 893
Query: 753 KLKATD---QEKSRKL------HELTVMQDRRE-----------------QARQDLKGLE 786
K+K + Q K R+L H T++++++ Q ++++ E
Sbjct: 894 KIKPVEYRLQYKERQLQYLLQNHLPTLLEEKQRAFEILDRGPLSLDNTLYQVEKEMEEKE 953
Query: 787 ETVAKELQTLHNLRKL-----FVQDLATRVKKSAEIDSDDTGGSAAQKQKISFLENNLEQ 841
E +A+ + L+KL F ++A + +K + + + + +KQ+ LE L +
Sbjct: 954 EQLAQYQANANQLQKLQATFEFTANIARQEEKVRKKEKEIL--ESREKQQREALERALAR 1011
Query: 842 LTKVHKQLVRDNADLRCELPKLEKR---LRATAERVKALESALKEAKENASRDRKRYQQE 898
L + H L R ++ L E+ + ++ L + + L+++L+ +E +D++R + E
Sbjct: 1012 LERRHSALQR-HSTLGMEIEEQRQKLASLNSGSREQSGLQASLEAEQEALEKDQERLEYE 1070
Query: 899 VDRIKEAVRSKNMARRGHSAQIAKPIRPGQHPAAS 933
+ ++K+ + + ++ H + + P ++
Sbjct: 1071 IQQLKQKIYEVDGVQKDHHGTLEGKVASSSLPVSA 1105
Score = 74.3 bits (181), Expect = 5e-13
Identities = 117/535 (21%), Positives = 231/535 (43%), Gaps = 67/535 (12%)
Query: 419 RKCEEEIAKLYKQLDDKDEEINQQSQLVEKLKTQMLDQEELLASTRRDQDN----MQAEL 474
RK EE + + +++K +++ + + E+ ++ +Q+E+ +R ++ +Q EL
Sbjct: 652 RKQEESLKRRSFHIENKLKDLLAEKEKFEE--ERLREQQEIELQKKRQEEETFLRVQEEL 709
Query: 475 NRLQAENDASKEEVKEVLQALEELAVNYDQKSQEVEDKTKEYELLSDELNQKSATLASID 534
RL+ N+ K E ++ Q L++L D++ ++E + K E ++ ++ +A ++
Sbjct: 710 QRLKELNNNEKAEKFQIFQELDQLQKEKDEQYAKLELEKKRLE---EQEKEQVMLVAHLE 766
Query: 535 AELQKLKEMTNHQKKRAAEMMASLLKDLAEIGIAVGNNDVKQPEGTGMID-EEFTVARLY 593
+L++ +EM ++ + + +DL GI VK+ G D EE A+L
Sbjct: 767 EQLREKQEMIQLLRRGEVQWVEEEKRDLE--GIRESLLRVKEARAGGDEDGEELEKAQLR 824
Query: 594 ISKMKSEVKTMVKRCKQLESTQTESNKKMEENEKELAAC--------QLRISQHEAKIKS 645
+ K + ++ Q + KK + E+E+ C + +H+ +
Sbjct: 825 FFEFKRRQLVKLVNLEKDLVQQKDILKKEVQEEQEILECLKCEHDKESRLLEKHDESVTD 884
Query: 646 LTEYLQNVEQ----------KKRQ----LEESVDALSEELVQ---------LRAQEKVHE 682
+TE Q+ E+ K+RQ L+ + L EE + L +++
Sbjct: 885 VTEVPQDFEKIKPVEYRLQYKERQLQYLLQNHLPTLLEEKQRAFEILDRGPLSLDNTLYQ 944
Query: 683 MEKEHLNKVQTANEVKQAVEQQIQSHRETHQ--KQISSLRDEVEAKAKLITDLQDQNQKM 740
+EKE K + + QA Q+Q + T + I+ ++V K K I + +++ Q+
Sbjct: 945 VEKEMEEKEEQLAQY-QANANQLQKLQATFEFTANIARQEEKVRKKEKEILESREKQQRE 1003
Query: 741 MLEQERLRVE--------HEKLKATDQEKSRKLHELTVMQDRREQARQDLKGLEETVAKE 792
LE+ R+E H L +E+ +KL L REQ+ GL+ ++ E
Sbjct: 1004 ALERALARLERRHSALQRHSTLGMEIEEQRQKLASLN--SGSREQS-----GLQASLEAE 1056
Query: 793 LQTLHNLRKLFVQDLATRVKKSAEID--SDDTGGSAAQKQKISFLENNLEQLTKVHKQLV 850
+ L ++ ++ +K E+D D G+ K S L + E+ V
Sbjct: 1057 QEALEKDQERLEYEIQQLKQKIYEVDGVQKDHHGTLEGKVASSSLPVSAEKSHLVPLMDA 1116
Query: 851 RDNADLRCELP-KLEKRLRATAERVKALESALK--EAKENASRDRK-RYQQEVDR 901
R NA + E+ +L+ R +E +K E N + RK +Y++ V R
Sbjct: 1117 RINAYIEEEVQRRLQDLHRVISEGCSTSADTMKDNEKLHNGTIQRKLKYERMVSR 1171
Score = 43.5 bits (101), Expect = 0.001
Identities = 94/472 (19%), Positives = 190/472 (40%), Gaps = 101/472 (21%)
Query: 333 VELTAEQWKKKYEKEKEKNKILRNTIQWLENELNRWRNGETVPIDEQFDKEKANLEAFTV 392
V L A ++ EK++ + R +QW+E +EK +LE
Sbjct: 759 VMLVAHLEEQLREKQEMIQLLRRGEVQWVE-------------------EEKRDLEGIRE 799
Query: 393 DKDITLTNDKPATAIGVIGNFTDAERRKCEEEIAKLYK-------QLDDKDEEINQQSQL 445
+L K A A G D + + E+ + ++ +L + ++++ QQ +
Sbjct: 800 ----SLLRVKEARAGG------DEDGEELEKAQLRFFEFKRRQLVKLVNLEKDLVQQKDI 849
Query: 446 VEKLKTQMLDQEELLASTRRDQDNMQAELNRLQAENDASKEEVKEVLQALEEL-AVNYDQ 504
LK ++ +++E+L + + D + +RL ++D S +V EV Q E++ V Y
Sbjct: 850 ---LKKEVQEEQEILECLKCEHD----KESRLLEKHDESVTDVTEVPQDFEKIKPVEYRL 902
Query: 505 KSQE--------------VEDKTKEYELLSDELNQKSATLASIDAELQKLKEMTNHQKKR 550
+ +E +E+K + +E+L TL ++ E+++ +E +
Sbjct: 903 QYKERQLQYLLQNHLPTLLEEKQRAFEILDRGPLSLDNTLYQVEKEMEEKEEQLAQYQAN 962
Query: 551 AAEMMASLLKDLAEIGIAVGNNDVKQPEGTGMIDEEFTVARLYISKMKSEVKTMVKRCKQ 610
A N +++ + T EFT I++ + +V R K+
Sbjct: 963 A--------------------NQLQKLQAT----FEFTA---NIARQEEKV-----RKKE 990
Query: 611 LESTQTESNKKMEENEKELAACQLRISQHEAKIKSLTEYLQNVEQKKRQLEESVDALSEE 670
E ++ ++ E E+ LA + R S + + +L ++ QK L S
Sbjct: 991 KEILESREKQQREALERALARLERRHSALQ-RHSTLGMEIEEQRQKLASLNSGSREQSGL 1049
Query: 671 LVQLRAQEKVHEMEKEHLN-KVQTANEVKQAVEQQIQSHRETHQKQISSLRDEVEAKAKL 729
L A+++ E ++E L ++Q + V+ + H T + +++S V A+
Sbjct: 1050 QASLEAEQEALEKDQERLEYEIQQLKQKIYEVDGVQKDHHGTLEGKVASSSLPVSAEKSH 1109
Query: 730 ITDLQDQNQKMMLEQE---RLRVEHEKL------KATDQEKSRKLHELTVMQ 772
+ L D +E+E RL+ H + A + + KLH T+ +
Sbjct: 1110 LVPLMDARINAYIEEEVQRRLQDLHRVISEGCSTSADTMKDNEKLHNGTIQR 1161
>gi|203096856 kinesin family member 7 [Homo sapiens]
Length = 1343
Score = 243 bits (620), Expect = 6e-64
Identities = 264/1027 (25%), Positives = 451/1027 (43%), Gaps = 142/1027 (13%)
Query: 6 ECNIKVMCRFRPLNESEVNRGDKYIAKFQ-GEDTVVIA-SKPYAFDRVFQSSTSQEQVYN 63
E ++V R RPL E+ G + + + G V + + + F V QE VY
Sbjct: 13 EAPVRVALRVRPLLPKELLHGHQSCLQVEPGLGRVTLGRDRHFGFHVVLAEDAGQEAVYQ 72
Query: 64 DCAKKIVKDVLEGYNGTIFAYGQTSSGKTHTM-----EGKLHDPEGMGIIPRIVQDIFNY 118
C + +++ EG+N T+FAYGQT SGKT+TM L D +G I+PR + + F
Sbjct: 73 ACVQPLLEAFFEGFNATVFAYGQTGSGKTYTMGEASVASLLEDEQG--IVPRAMAEAFKL 130
Query: 119 IYSMDEN--LEFHIKVSYFEIYLDKIRDLLDV--SKTNLSVHEDKNRVPYVKGCTERFVC 174
I DEN L+ + VSY E+Y ++ RDLL+V + ++ + ED+ + G E V
Sbjct: 131 I---DENDLLDCLVHVSYLEVYKEEFRDLLEVGTASRDIQLREDERGNVVLCGVKEVDVE 187
Query: 175 SPDEVMDTIDEGKSNRHVAVTNMNEHSSRSHSIFLINVKQENTQTE--------QKLSGK 226
DEV+ ++ G + RH T++N SSRSH++F + ++Q Q L K
Sbjct: 188 GLDEVLSLLEMGNAARHTGATHLNHLSSRSHTVFTVTLEQRGRAPSRLPRPAPGQLLVSK 247
Query: 227 LYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAEGS---TYVPYRDSKMT 283
+ VDLAGSE+V KTG+ G L E+ IN SL ALGNVISAL + +++PYRDSK+T
Sbjct: 248 FHFVDLAGSERVLKTGSTGERLKESIQINSSLLALGNVISALGDPQRRGSHIPYRDSKIT 307
Query: 284 RILQDSLGGNCRTTIVICCSPSSYNESETKSTLLFGQRAKTIKNTVCVNVELTAEQWKKK 343
RIL+DSLGGN +T ++ C SPSS + ET +TL + RA+ I+N VN W+ +
Sbjct: 308 RILKDSLGGNAKTVMIACVSPSSSDFDETLNTLNYASRAQNIRNRATVN-------WRPE 360
Query: 344 YEKEKEKNKILRNTIQWLENELNRWRNGETVP--------IDEQFDKEKANLEAFTVDKD 395
E+ E+ +E G P + E A A T D
Sbjct: 361 AERPPEETASGARGPPRHRSETRIIHRGRRAPGPATASAAAAMRLGAECARYRACT-DAA 419
Query: 396 ITLTNDKPATAIGVIGNFTDAERRKCEEEIAKLYKQLDDKDEEINQQSQLVEKLKTQMLD 455
+L + A G+ G A RK + + ++ + ++ S +++ ++
Sbjct: 420 YSLLRELQAEP-GLPG----AAARKVRDWLC----AVEGERSALSSASGPDSGIESASVE 470
Query: 456 QEELLASTRRDQDNMQAELNRLQAENDASKEEVKEVLQALEELAVNYDQKSQEVEDKTKE 515
+ + R +D +L LQ + +EE ++ L ALE+ Y +S + ++ +E
Sbjct: 471 DQAAQGAGGRKEDEGAQQLLTLQNQVARLEEENRDFLAALEDAMEQYKLQSDRLREQQEE 530
Query: 516 YELLSDEL-----------------------NQKSATLASIDAELQKL------------ 540
L L +A L A + +
Sbjct: 531 MVELRLRLELVRPGWGGPRLLNGLPPGSFVPRPHTAPLGGAHAHVLGMVPPACLPGDEVG 590
Query: 541 KEMTNHQKKRAAEMMASLLKDLAEIGIAVGNNDVKQPEGTGMIDEEFTVARLYISKMKSE 600
E Q E A LL ++ +G G++ + E +EE R + ++
Sbjct: 591 SEQRGEQVTNGREAGAELLTEVNRLG--SGSSAASEEE-----EEEEEPPRRTLHLRRNR 643
Query: 601 VKTMVKRCKQLESTQTESNKK---MEE------NEKELAACQLRISQHEAKIKSLTEY-L 650
+ +R + E +EE + + + R+ + + +E+ L
Sbjct: 644 ISNCSQRAGARPGSLPERKGPELCLEELDAAIPGSRAVGGSKARVQARQVPPATASEWRL 703
Query: 651 QNVEQKKRQLEESVDALSEELV--QLRAQEKVHEMEKEHLNKVQTANEVKQAVEQQIQSH 708
+QK R+L ++ + EEL+ +R + + ++H +++ E++Q E Q+++
Sbjct: 704 AQAQQKIRELAINI-RMKEELIGELVRTGKAAQALNRQHSQRIR---ELEQEAE-QVRAE 758
Query: 709 RETHQKQISSLRDEVEAKAKLITDLQDQNQKMMLEQERLRVEHEKLKATDQ------EKS 762
Q+Q+ L + A + LQ+ +++ Q +++V EK +AT++ +
Sbjct: 759 LSEGQRQLRELEGKELQDAGERSRLQEFRRRVAAAQSQVQVLKEKKQATERLVSLSAQSE 818
Query: 763 RKLHEL--TVMQDRREQARQDLKGLEETV---------------AKELQTLH----NLRK 801
++L EL V R++Q + + EET KEL+ H + K
Sbjct: 819 KRLQELERNVQLMRQQQGQLQRRLREETEQKRRLEAEMSKRQHRVKELELKHEQQQKILK 878
Query: 802 LFVQDLATRVKKSAEIDSDDTGGSAAQKQKISFLENNLEQLTKVHKQLVRDNADLRCELP 861
+ +++A +K S+ + S Q+QKI + L+Q + Q R +L EL
Sbjct: 879 IKTEEIAAFQRKRRS-GSNGSVVSLEQQQKIEEQKKWLDQEMEKVLQQRRALEELGEELH 937
Query: 862 KLEKRL---RATAERVKALESALKEAKENASRDRKRYQQEVDRIKEAVRSKNMARRGHSA 918
K E L A + LES + + + D R ++ +++ + K+ R SA
Sbjct: 938 KREAILAKKEALMQEKTGLESKRLRSSQALNEDIVRVSSRLEHLEKELSEKSGQLRQGSA 997
Query: 919 QIAKPIR 925
Q + IR
Sbjct: 998 QSQQQIR 1004
Score = 62.8 bits (151), Expect = 2e-09
Identities = 83/395 (21%), Positives = 178/395 (45%), Gaps = 43/395 (10%)
Query: 417 ERRKCEEEIAKLYKQLDDKDEEINQQSQLVEKLKTQMLDQEELLASTRRDQDNMQAELNR 476
++R+ E E++K ++ + + + QQ +++ K+KT EE+ A R+ + +
Sbjct: 848 QKRRLEAEMSKRQHRVKELELKHEQQQKIL-KIKT-----EEIAAFQRKRRSGSNGSVVS 901
Query: 477 LQAENDASKEEVKEVLQALEELAVNYDQKSQEVEDKTKEYELLSDELNQKSATLASIDAE 536
L+ + Q +EE DQ+ ++V + + E L +EL+++ A LA +A
Sbjct: 902 LEQQ------------QKIEEQKKWLDQEMEKVLQQRRALEELGEELHKREAILAKKEAL 949
Query: 537 LQKLKEMTNHQKKRAAEMMASLLKDLAEIGIAVGNNDVKQPEGTGMIDEEFTVA----RL 592
+Q E T + KR A L +D+ + + + + + E +G + + + R
Sbjct: 950 MQ---EKTGLESKRLRSSQA-LNEDIVRVSSRLEHLEKELSEKSGQLRQGSAQSQQQIRG 1005
Query: 593 YISKMKSEVKTMVKRCKQLESTQTESNKKMEENEKELAACQLRISQHEAKIKSLTEYLQN 652
I ++ E +++K+ +++ + + E E+ L I +A I+ E
Sbjct: 1006 EIDSLRQEKDSLLKQRLEIDGKLRQGSLLSPEEERTLFQLDEAIEALDAAIEYKNE---A 1062
Query: 653 VEQKKRQLEESVDALSEELVQLRAQEKVHEMEKEHLNKVQTANEVKQAVEQQIQSHRETH 712
+ ++R L S LS+ + L A + +L+ +T + + ++ + E H
Sbjct: 1063 ITCRQRVLRASASLLSQCEMNLMA-------KLSYLSSSETRALLCKYFDKVVTLREEQH 1115
Query: 713 QKQI--SSLRDEVEAKAKLITDLQDQNQKMMLEQER----LRVEHEKLKATDQEKSRKLH 766
Q+QI S L ++E + +L+ L+ ++ LE +R + EHE+ ++SR H
Sbjct: 1116 QQQIAFSELEMQLEEQQRLVYWLEVALERQRLEMDRQLTLQQKEHEQNMQLLLQQSRD-H 1174
Query: 767 ELTVMQDRREQARQDLKGLEETVAKELQTLHNLRK 801
+ D R Q ++ LE+ + + + L++
Sbjct: 1175 LGEGLADSRRQYEARIQALEKELGRYMWINQELKQ 1209
Score = 53.5 bits (127), Expect = 9e-07
Identities = 78/418 (18%), Positives = 171/418 (40%), Gaps = 50/418 (11%)
Query: 483 ASKEEVKEVLQALEELAVNYDQKSQEVEDKTKEYELLSDELNQKSATLASIDAELQKLKE 542
AS+ + + Q + ELA+N K + + + + + Q S + ++ E ++++
Sbjct: 698 ASEWRLAQAQQKIRELAINIRMKEELIGELVRTGKAAQALNRQHSQRIRELEQEAEQVRA 757
Query: 543 MTNHQKKRAAEMMASLLKDLAEIG--------IAVGNNDVK----QPEGTGMIDEEFTVA 590
+ +++ E+ L+D E +A + V+ + + T + +
Sbjct: 758 ELSEGQRQLRELEGKELQDAGERSRLQEFRRRVAAAQSQVQVLKEKKQATERLVSLSAQS 817
Query: 591 RLYISKMKSEVKTMVKRCKQLESTQTESNKKMEENEKELAACQLRISQHEAK-------I 643
+ +++ V+ M ++ QL+ E ++ E E++ Q R+ + E K +
Sbjct: 818 EKRLQELERNVQLMRQQQGQLQRRLREETEQKRRLEAEMSKRQHRVKELELKHEQQQKIL 877
Query: 644 KSLTEYLQNVEQKKRQLEESVDALSEELVQLRAQEKVHEMEKEHLNKVQTANEVKQAVEQ 703
K TE + ++K+R + +V L Q+K+ E +K +++ + ++A+E
Sbjct: 878 KIKTEEIAAFQRKRR------SGSNGSVVSLEQQQKIEEQKKWLDQEMEKVLQQRRALE- 930
Query: 704 QIQSHRETHQKQISSLRDEVEAKAKLITDLQDQNQKMMLEQERLRVEHEKLKATDQEKSR 763
+ E H+ R+ + AK + + +K LE +RLR + + SR
Sbjct: 931 --ELGEELHK------REAILAKKEAL-----MQEKTGLESKRLRSSQALNEDIVRVSSR 977
Query: 764 KLHELTVMQDRREQARQDLKGLEETVAKELQTLHNLRKLFVQDLATRVKKSAEIDSDDTG 823
H + ++ Q RQ ++ + E+ +L Q+ + +K+ EID
Sbjct: 978 LEHLEKELSEKSGQLRQGSAQSQQQIRGEIDSLR-------QEKDSLLKQRLEIDGKLRQ 1030
Query: 824 GSAAQKQKISFLENNLEQLTKVHKQLVRDNADLRCELPKLEKRLRATAERVKALESAL 881
GS ++ L E + + + N + C ++ LRA+A + E L
Sbjct: 1031 GSLLSPEEERTLFQLDEAIEALDAAIEYKNEAITCR----QRVLRASASLLSQCEMNL 1084
>gi|41352705 kinesin family member 3C [Homo sapiens]
Length = 793
Score = 241 bits (615), Expect = 2e-63
Identities = 183/597 (30%), Positives = 292/597 (48%), Gaps = 72/597 (12%)
Query: 9 IKVMCRFRPLNESEVNRGDKYIAKFQGEDTVVIASKP----------YAFDRVFQSSTSQ 58
+KV+ R RPL+ E G + I + V P + FD V+ +S+ Q
Sbjct: 11 LKVVARCRPLSRKEEAAGHEQILTMDVKLGQVTLRNPRAAPGELPKTFTFDAVYDASSKQ 70
Query: 59 EQVYNDCAKKIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPEGMGIIPRIVQDIFNY 118
+Y++ + ++ VL+G+NGT+FAYGQT +GKT+TM+G +PE G+IP + IF +
Sbjct: 71 ADLYDETVRPLIDSVLQGFNGTVFAYGQTGTGKTYTMQGTWVEPELRGVIPNAFEHIFTH 130
Query: 119 IYSMDENLEFHIKVSYFEIYLDKIRDLLDVSK-TNLSVHEDKNRVPYVKGCTERFVCSPD 177
I S +N ++ ++ SY EIY ++IRDLL L + E+ Y+K + +
Sbjct: 131 I-SRSQNQQYLVRASYLEIYQEEIRDLLSKEPGKRLELKENPETGVYIKDLSSFVTKNVK 189
Query: 178 EVMDTIDEGKSNRHVAVTNMNEHSSRSHSIFLINVKQENTQTEQK---LSGKLYLVDLAG 234
E+ ++ G R V T+MNE SSRSH+IF+I V+ ++ + GKL LVDLAG
Sbjct: 190 EIEHVMNLGNQTRAVGSTHMNEVSSRSHAIFIITVECSERGSDGQDHIRVGKLNLVDLAG 249
Query: 235 SEKVSKT------------------------GAEGAVLDEAKNINKSLSALGNVISALA- 269
SE+ +K GA G EA IN SLSALGNVI+ALA
Sbjct: 250 SERQNKAGPNTAGGAATPSSGGGGGGGGSGGGAGGERPKEASKINLSLSALGNVIAALAG 309
Query: 270 EGSTYVPYRDSKMTRILQDSLGGNCRTTIVICCSPSSYNESETKSTLLFGQRAKTIKNTV 329
ST++PYRDSK+TR+LQDSLGGN +T +V P+S++ E+ STL F RAK IKN
Sbjct: 310 NRSTHIPYRDSKLTRLLQDSLGGNAKTIMVATLGPASHSYDESLSTLRFANRAKNIKNKP 369
Query: 330 CVNVELTAEQWKKKYEKE--KEKNKILRNTIQWLENELNRWRNGETVPIDEQFDKEKANL 387
VN E + +++++E + K ++ + + R + V + E +
Sbjct: 370 RVN-EDPKDTLLREFQEEIARLKAQLEKRGMLGKRPRRKSSRRKKAVSAPPGY-PEGPVI 427
Query: 388 EAFTV-DKDITLTNDKPATAIGVIGNFTDAERRKCEEEIAKLYKQLDDKDEEINQQSQLV 446
EA+ ++D N +P I A + E + + ++L+++ I LV
Sbjct: 428 EAWVAEEEDDNNNNHRPPQPI-----LESALEKNMENYLQEQKERLEEEKAAIQDDRSLV 482
Query: 447 EKLKTQMLDQ-EELLASTRRDQD---------------------NMQAELNRLQAENDAS 484
+ K ++L++ E++L RR+Q N+ N Q +
Sbjct: 483 SEEKQKLLEEKEKMLEDLRREQQATELLAAKYKAMESKLLIGGRNIMDHTNEQQKMLELK 542
Query: 485 KEEVKEVLQALEELAVNYDQKSQEVEDKTKEYELLSDELNQKSATLASIDAELQKLK 541
++E+ E + E+ + +E + Y L E+ K+ L + A+LQ +K
Sbjct: 543 RQEIAEQKRREREMQQEMMLRDEETMELRGTYTSLQQEVEVKTKKLKKLYAKLQAVK 599
Score = 45.8 bits (107), Expect = 2e-04
Identities = 52/190 (27%), Positives = 90/190 (47%), Gaps = 35/190 (18%)
Query: 644 KSLTEYLQNVEQKKRQLEESVDALSEE--LVQLRAQEKVHEMEK--EHLNKVQTANEVKQ 699
K++ YLQ EQK+R LEE A+ ++ LV Q+ + E EK E L + Q A E+
Sbjct: 455 KNMENYLQ--EQKER-LEEEKAAIQDDRSLVSEEKQKLLEEKEKMLEDLRREQQATELLA 511
Query: 700 AVEQQIQS-----------HRETHQKQISSLRDEVEAKAKLITDLQDQNQKMMLEQER-- 746
A + ++S H QK + R E+ + + ++Q Q+MML E
Sbjct: 512 AKYKAMESKLLIGGRNIMDHTNEQQKMLELKRQEIAEQKRREREMQ---QEMMLRDEETM 568
Query: 747 -LRVEHEKLKATDQEKSRKLHELTV--------MQDRREQ---ARQDLKGLEETVAKELQ 794
LR + L+ + K++KL +L +QD+ ++ RQDL+ + +EL+
Sbjct: 569 ELRGTYTSLQQEVEVKTKKLKKLYAKLQAVKAEIQDQHDEYIRVRQDLEEAQNEQTRELK 628
Query: 795 TLHNLRKLFV 804
+ + + F+
Sbjct: 629 LKYLIIENFI 638
>gi|157738629 kinesin family member 13A isoform d [Homo sapiens]
Length = 1749
Score = 237 bits (605), Expect = 3e-62
Identities = 158/422 (37%), Positives = 236/422 (55%), Gaps = 47/422 (11%)
Query: 4 LAECNIKVMCRFRPLNESEVNRGDKYIAKFQGEDTVVIAS------------KPYAFDRV 51
+++ +KV R RP+N E+ K + + +G TV+ K +AFD
Sbjct: 1 MSDTKVKVAVRVRPMNRRELELNTKCVVEMEGNQTVLHPPPSNTKQGERKPPKVFAFDYC 60
Query: 52 F----QSSTS----QEQVYNDCAKKIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPE 103
F +S+T+ QE V+ + I++ +GYN IFAYGQT SGK+ +M G E
Sbjct: 61 FWSMDESNTTKYAGQEVVFKCLGEGILEKAFQGYNACIFAYGQTGSGKSFSMMGHA---E 117
Query: 104 GMGIIPRIVQDIFNYI-YSMDENLEFHIKVSYFEIYLDKIRDLLDV--SKTNLSVHEDKN 160
+G+IPR+ +F I +E+ F ++VSY EIY +K+RDLLD S+ +L V E K
Sbjct: 118 QLGLIPRLCCALFKRISLEQNESQTFKVEVSYMEIYNEKVRDLLDPKGSRQSLKVREHKV 177
Query: 161 RVPYVKGCTERFVCSPDEVMDTIDEGKSNRHVAVTNMNEHSSRSHSIFLINVKQENTQTE 220
PYV G ++ V S +++ + EG +R VA TNMNE SSRSH++F I + Q +
Sbjct: 178 LGPYVDGLSQLAVTSFEDIESLMSEGNKSRTVAATNMNEESSRSHAVFNIIITQTLYDLQ 237
Query: 221 QKLSG----KLYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAEG----- 271
SG K+ LVDLAGSE+VSKTGA G L E NINKSL+ LG VIS+LA+
Sbjct: 238 SGNSGEKVSKVSLVDLAGSERVSKTGAAGERLKEGSNINKSLTTLGLVISSLADQAAGKG 297
Query: 272 -STYVPYRDSKMTRILQDSLGGNCRTTIVICCSPSSYNESETKSTLLFGQRAKTIKNTVC 330
S +VPYRDS +T +L+D+LGGN +T+++ SP++ N ET STL + RAK I N
Sbjct: 298 KSKFVPYRDSVLTWLLKDNLGGNSQTSMIATISPAADNYEETLSTLRYADRAKRIVNHAV 357
Query: 331 VNVELTAEQWKKKYEKEKEKNKILRNTIQWLENELNRWRNGETVPIDEQFDKEKANLEAF 390
VN + A+ ++ LR ++ L +L++ + + E+ ++ + ++
Sbjct: 358 VNEDPNAKVIRE-----------LREEVEKLREQLSQAEAMKAPELKEKLEESEKLIKEL 406
Query: 391 TV 392
TV
Sbjct: 407 TV 408
>gi|157738627 kinesin family member 13A isoform c [Homo sapiens]
Length = 1757
Score = 237 bits (605), Expect = 3e-62
Identities = 158/422 (37%), Positives = 236/422 (55%), Gaps = 47/422 (11%)
Query: 4 LAECNIKVMCRFRPLNESEVNRGDKYIAKFQGEDTVVIAS------------KPYAFDRV 51
+++ +KV R RP+N E+ K + + +G TV+ K +AFD
Sbjct: 1 MSDTKVKVAVRVRPMNRRELELNTKCVVEMEGNQTVLHPPPSNTKQGERKPPKVFAFDYC 60
Query: 52 F----QSSTS----QEQVYNDCAKKIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPE 103
F +S+T+ QE V+ + I++ +GYN IFAYGQT SGK+ +M G E
Sbjct: 61 FWSMDESNTTKYAGQEVVFKCLGEGILEKAFQGYNACIFAYGQTGSGKSFSMMGHA---E 117
Query: 104 GMGIIPRIVQDIFNYI-YSMDENLEFHIKVSYFEIYLDKIRDLLDV--SKTNLSVHEDKN 160
+G+IPR+ +F I +E+ F ++VSY EIY +K+RDLLD S+ +L V E K
Sbjct: 118 QLGLIPRLCCALFKRISLEQNESQTFKVEVSYMEIYNEKVRDLLDPKGSRQSLKVREHKV 177
Query: 161 RVPYVKGCTERFVCSPDEVMDTIDEGKSNRHVAVTNMNEHSSRSHSIFLINVKQENTQTE 220
PYV G ++ V S +++ + EG +R VA TNMNE SSRSH++F I + Q +
Sbjct: 178 LGPYVDGLSQLAVTSFEDIESLMSEGNKSRTVAATNMNEESSRSHAVFNIIITQTLYDLQ 237
Query: 221 QKLSG----KLYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAEG----- 271
SG K+ LVDLAGSE+VSKTGA G L E NINKSL+ LG VIS+LA+
Sbjct: 238 SGNSGEKVSKVSLVDLAGSERVSKTGAAGERLKEGSNINKSLTTLGLVISSLADQAAGKG 297
Query: 272 -STYVPYRDSKMTRILQDSLGGNCRTTIVICCSPSSYNESETKSTLLFGQRAKTIKNTVC 330
S +VPYRDS +T +L+D+LGGN +T+++ SP++ N ET STL + RAK I N
Sbjct: 298 KSKFVPYRDSVLTWLLKDNLGGNSQTSMIATISPAADNYEETLSTLRYADRAKRIVNHAV 357
Query: 331 VNVELTAEQWKKKYEKEKEKNKILRNTIQWLENELNRWRNGETVPIDEQFDKEKANLEAF 390
VN + A+ ++ LR ++ L +L++ + + E+ ++ + ++
Sbjct: 358 VNEDPNAKVIRE-----------LREEVEKLREQLSQAEAMKAPELKEKLEESEKLIKEL 406
Query: 391 TV 392
TV
Sbjct: 407 TV 408
>gi|157738625 kinesin family member 13A isoform b [Homo sapiens]
Length = 1770
Score = 237 bits (605), Expect = 3e-62
Identities = 158/422 (37%), Positives = 236/422 (55%), Gaps = 47/422 (11%)
Query: 4 LAECNIKVMCRFRPLNESEVNRGDKYIAKFQGEDTVVIAS------------KPYAFDRV 51
+++ +KV R RP+N E+ K + + +G TV+ K +AFD
Sbjct: 1 MSDTKVKVAVRVRPMNRRELELNTKCVVEMEGNQTVLHPPPSNTKQGERKPPKVFAFDYC 60
Query: 52 F----QSSTS----QEQVYNDCAKKIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPE 103
F +S+T+ QE V+ + I++ +GYN IFAYGQT SGK+ +M G E
Sbjct: 61 FWSMDESNTTKYAGQEVVFKCLGEGILEKAFQGYNACIFAYGQTGSGKSFSMMGHA---E 117
Query: 104 GMGIIPRIVQDIFNYI-YSMDENLEFHIKVSYFEIYLDKIRDLLDV--SKTNLSVHEDKN 160
+G+IPR+ +F I +E+ F ++VSY EIY +K+RDLLD S+ +L V E K
Sbjct: 118 QLGLIPRLCCALFKRISLEQNESQTFKVEVSYMEIYNEKVRDLLDPKGSRQSLKVREHKV 177
Query: 161 RVPYVKGCTERFVCSPDEVMDTIDEGKSNRHVAVTNMNEHSSRSHSIFLINVKQENTQTE 220
PYV G ++ V S +++ + EG +R VA TNMNE SSRSH++F I + Q +
Sbjct: 178 LGPYVDGLSQLAVTSFEDIESLMSEGNKSRTVAATNMNEESSRSHAVFNIIITQTLYDLQ 237
Query: 221 QKLSG----KLYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAEG----- 271
SG K+ LVDLAGSE+VSKTGA G L E NINKSL+ LG VIS+LA+
Sbjct: 238 SGNSGEKVSKVSLVDLAGSERVSKTGAAGERLKEGSNINKSLTTLGLVISSLADQAAGKG 297
Query: 272 -STYVPYRDSKMTRILQDSLGGNCRTTIVICCSPSSYNESETKSTLLFGQRAKTIKNTVC 330
S +VPYRDS +T +L+D+LGGN +T+++ SP++ N ET STL + RAK I N
Sbjct: 298 KSKFVPYRDSVLTWLLKDNLGGNSQTSMIATISPAADNYEETLSTLRYADRAKRIVNHAV 357
Query: 331 VNVELTAEQWKKKYEKEKEKNKILRNTIQWLENELNRWRNGETVPIDEQFDKEKANLEAF 390
VN + A+ ++ LR ++ L +L++ + + E+ ++ + ++
Sbjct: 358 VNEDPNAKVIRE-----------LREEVEKLREQLSQAEAMKAPELKEKLEESEKLIKEL 406
Query: 391 TV 392
TV
Sbjct: 407 TV 408
>gi|157738621 kinesin family member 13A isoform a [Homo sapiens]
Length = 1805
Score = 237 bits (605), Expect = 3e-62
Identities = 158/422 (37%), Positives = 236/422 (55%), Gaps = 47/422 (11%)
Query: 4 LAECNIKVMCRFRPLNESEVNRGDKYIAKFQGEDTVVIAS------------KPYAFDRV 51
+++ +KV R RP+N E+ K + + +G TV+ K +AFD
Sbjct: 1 MSDTKVKVAVRVRPMNRRELELNTKCVVEMEGNQTVLHPPPSNTKQGERKPPKVFAFDYC 60
Query: 52 F----QSSTS----QEQVYNDCAKKIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPE 103
F +S+T+ QE V+ + I++ +GYN IFAYGQT SGK+ +M G E
Sbjct: 61 FWSMDESNTTKYAGQEVVFKCLGEGILEKAFQGYNACIFAYGQTGSGKSFSMMGHA---E 117
Query: 104 GMGIIPRIVQDIFNYI-YSMDENLEFHIKVSYFEIYLDKIRDLLDV--SKTNLSVHEDKN 160
+G+IPR+ +F I +E+ F ++VSY EIY +K+RDLLD S+ +L V E K
Sbjct: 118 QLGLIPRLCCALFKRISLEQNESQTFKVEVSYMEIYNEKVRDLLDPKGSRQSLKVREHKV 177
Query: 161 RVPYVKGCTERFVCSPDEVMDTIDEGKSNRHVAVTNMNEHSSRSHSIFLINVKQENTQTE 220
PYV G ++ V S +++ + EG +R VA TNMNE SSRSH++F I + Q +
Sbjct: 178 LGPYVDGLSQLAVTSFEDIESLMSEGNKSRTVAATNMNEESSRSHAVFNIIITQTLYDLQ 237
Query: 221 QKLSG----KLYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAEG----- 271
SG K+ LVDLAGSE+VSKTGA G L E NINKSL+ LG VIS+LA+
Sbjct: 238 SGNSGEKVSKVSLVDLAGSERVSKTGAAGERLKEGSNINKSLTTLGLVISSLADQAAGKG 297
Query: 272 -STYVPYRDSKMTRILQDSLGGNCRTTIVICCSPSSYNESETKSTLLFGQRAKTIKNTVC 330
S +VPYRDS +T +L+D+LGGN +T+++ SP++ N ET STL + RAK I N
Sbjct: 298 KSKFVPYRDSVLTWLLKDNLGGNSQTSMIATISPAADNYEETLSTLRYADRAKRIVNHAV 357
Query: 331 VNVELTAEQWKKKYEKEKEKNKILRNTIQWLENELNRWRNGETVPIDEQFDKEKANLEAF 390
VN + A+ ++ LR ++ L +L++ + + E+ ++ + ++
Sbjct: 358 VNEDPNAKVIRE-----------LREEVEKLREQLSQAEAMKAPELKEKLEESEKLIKEL 406
Query: 391 TV 392
TV
Sbjct: 407 TV 408
>gi|40254834 kinesin family member 1C [Homo sapiens]
Length = 1103
Score = 236 bits (602), Expect = 8e-62
Identities = 144/378 (38%), Positives = 215/378 (56%), Gaps = 28/378 (7%)
Query: 4 LAECNIKVMCRFRPLNESEVNRGDKYIAKFQGEDTVVI-------ASKPYAFDRVFQSST 56
+A ++KV R RP N E ++ K + QG T +I A K + FD + S T
Sbjct: 1 MAGASVKVAVRVRPFNARETSQDAKCVVSMQGNTTSIINPKQSKDAPKSFTFDYSYWSHT 60
Query: 57 S--------QEQVYNDCAKKIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPEGMGII 108
S Q+QVY D ++++ EGYN IFAYGQT +GK++TM G+ +P GI+
Sbjct: 61 STEDPQFASQQQVYRDIGEEMLLHAFEGYNVCIFAYGQTGAGKSYTMMGR-QEPGQQGIV 119
Query: 109 PRIVQDIFNYIY-SMDENLEFHIKVSYFEIYLDKIRDLLDV-SKTNLSVHEDKNRVPYVK 166
P++ +D+F+ + + L + ++VSY EIY +++RDLL+ S+ +L V E PYV+
Sbjct: 120 PQLCEDLFSRVSENQSAQLSYSVEVSYMEIYCERVRDLLNPKSRGSLRVREHPILGPYVQ 179
Query: 167 GCTERFVCSPDEVMDTIDEGKSNRHVAVTNMNEHSSRSHSIFLINVKQ----ENTQTEQK 222
++ V S ++ D +D G R VA TNMNE SSRSH++F I Q + T + +
Sbjct: 180 DLSKLAVTSYADIADLMDCGNKARTVAATNMNETSSRSHAVFTIVFTQRCHDQLTGLDSE 239
Query: 223 LSGKLYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAE------GSTYVP 276
K+ LVDLAGSE+ +GA G L E NINKSL+ LG VISALA+ S ++P
Sbjct: 240 KVSKISLVDLAGSERADSSGARGMRLKEGANINKSLTTLGKVISALADMQSKKRKSDFIP 299
Query: 277 YRDSKMTRILQDSLGGNCRTTIVICCSPSSYNESETKSTLLFGQRAKTIKNTVCVNVELT 336
YRDS +T +L+++LGGN RT ++ SP+ N ET STL + R K I+ +N +
Sbjct: 300 YRDSVLTWLLKENLGGNSRTAMIAALSPADINYEETLSTLRYADRTKQIRCNAIINEDPN 359
Query: 337 AEQWKKKYEKEKEKNKIL 354
A ++ E+ ++L
Sbjct: 360 ARLIRELQEEVARLRELL 377
>gi|46852172 kinesin family member 13B [Homo sapiens]
Length = 1826
Score = 226 bits (577), Expect = 6e-59
Identities = 148/384 (38%), Positives = 206/384 (53%), Gaps = 40/384 (10%)
Query: 4 LAECNIKVMCRFRPLNESEVNRGDKYIAKFQGEDTVVIA-------------SKPYAFDR 50
+ + +KV R RP+N E + K + ++ K +A+D
Sbjct: 1 MGDSKVKVAVRIRPMNRRETDLHTKCVVDVDANKVILNPVNTNLSKGDARGQPKVFAYDH 60
Query: 51 VFQSS--------TSQEQVYNDCAKKIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDP 102
F S Q+ V+ + I+++ +GYN IFAYGQT SGK++TM G P
Sbjct: 61 CFWSMDESVKEKYAGQDIVFKCLGENILQNAFDGYNACIFAYGQTGSGKSYTMMGTADQP 120
Query: 103 EGMGIIPRIVQDIFNYIYSMD-ENLEFHIKVSYFEIYLDKIRDLLDV--SKTNLSVHEDK 159
G+IPR+ +F + E F ++VSY EIY +K+RDLLD S+ L V E
Sbjct: 121 ---GLIPRLCSGLFERTQKEENEEQSFKVEVSYMEIYNEKVRDLLDPKGSRQTLKVREHS 177
Query: 160 NRVPYVKGCTERFVCSPDEVMDTIDEGKSNRHVAVTNMNEHSSRSHSIFLINVKQE---- 215
PYV G ++ V S ++ + EG +R VA TNMNE SSRSH++F I +
Sbjct: 178 VLGPYVDGLSKLAVTSYKDIESLMSEGNKSRTVAATNMNEESSRSHAVFKITLTHTLYDV 237
Query: 216 NTQTEQKLSGKLYLVDLAGSEKVSKTGAEGAVLDEAKNINKSLSALGNVISALAEGST-- 273
+ T + GKL LVDLAGSE+ +KTGA G L E NINKSL+ LG VISALA+ S
Sbjct: 238 KSGTSGEKVGKLSLVDLAGSERATKTGAAGDRLKEGSNINKSLTTLGLVISALADQSAGK 297
Query: 274 ----YVPYRDSKMTRILQDSLGGNCRTTIVICCSPSSYNESETKSTLLFGQRAKTIKNTV 329
+VPYRDS +T +L+DSLGGN +T +V SP++ N ET STL + RAK I N
Sbjct: 298 NKNKFVPYRDSVLTWLLKDSLGGNSKTAMVATVSPAADNYDETLSTLRYADRAKHIVNHA 357
Query: 330 CVNVELTA---EQWKKKYEKEKEK 350
VN + A +++ EK +E+
Sbjct: 358 VVNEDPNARIIRDLREEVEKLREQ 381
>gi|194294510 kinesin family member C3 isoform 2 [Homo sapiens]
Length = 826
Score = 222 bits (566), Expect = 1e-57
Identities = 134/329 (40%), Positives = 201/329 (61%), Gaps = 14/329 (4%)
Query: 8 NIKVMCRFRPLNESEVNRGDKYIA-KFQGEDTVVI----ASKPYAF--DRVFQSSTSQEQ 60
NI+V+ R RP+ + + + A F +D +I KP +F D+VF SQ+
Sbjct: 445 NIRVIARVRPVTKEDGEGPEATNAVTFDADDDSIIHLLHKGKPVSFELDKVFSPQASQQD 504
Query: 61 VYNDCAKKIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPEGMGIIPRIVQDIFNYIY 120
V+ + + +V ++G+N IFAYGQT +GKT+TMEG +P GI R +Q +F+ +
Sbjct: 505 VFQE-VQALVTSCIDGFNVCIFAYGQTGAGKTYTMEGTAENP---GINQRALQLLFSEVQ 560
Query: 121 SMDENLEFHIKVSYFEIYLDKIRDLLDVS---KTNLSVHEDKNRVPYVKGCTERFVCSPD 177
+ E+ I VS EIY + +RDLL K + + D + YV G TE V S D
Sbjct: 561 EKASDWEYTITVSAAEIYNEVLRDLLGKEPQEKLEIRLCPDGSGQLYVPGLTEFQVQSVD 620
Query: 178 EVMDTIDEGKSNRHVAVTNMNEHSSRSHSIFLINVKQENTQTEQKLSGKLYLVDLAGSEK 237
++ + G +NR TN+NEHSSRSH++ ++ V+ + T + +GKL LVDLAGSE+
Sbjct: 621 DINKVFEFGHTNRTTEFTNLNEHSSRSHALLIVTVRGVDCSTGLRTTGKLNLVDLAGSER 680
Query: 238 VSKTGAEGAVLDEAKNINKSLSALGNVISALAEGSTYVPYRDSKMTRILQDSLGGNCRTT 297
V K+GAEG+ L EA++INKSLSALG+VI+AL +VP+R+SK+T +LQDSL G+ +T
Sbjct: 681 VGKSGAEGSRLREAQHINKSLSALGDVIAALRSRQGHVPFRNSKLTYLLQDSLSGDSKTL 740
Query: 298 IVICCSPSSYNESETKSTLLFGQRAKTIK 326
+V+ SP N SET +L F +R ++++
Sbjct: 741 MVVQVSPVEKNTSETLYSLKFAERVRSVE 769
Score = 34.3 bits (77), Expect = 0.58
Identities = 43/214 (20%), Positives = 92/214 (42%), Gaps = 34/214 (15%)
Query: 714 KQISSLRDEVEAKAKLITDLQDQNQKMMLEQERLRVEHEKLKAT---------------- 757
+++S LR E+ TDL+ +M+E ERLR E + +A
Sbjct: 118 QEVSRLRSELGG-----TDLEKHRDLLMVENERLRQEMRRCEAELQELRTKPAGPCPGCE 172
Query: 758 -DQEKSRKLHELTVMQDRREQARQDLKGLEETVAKELQTLHNLRKLFVQDLATRVKKSAE 816
QE ++ +L+ +Q +++ L L V ++ L + LA + ++
Sbjct: 173 HSQESAQLRDKLSQLQLEMAESKGMLSELNLEVQQKTDRLAEVELRLKDCLAEKAQEEER 232
Query: 817 I-----DSDDTGGS-AAQKQKISFLENNLEQLTKVHKQLVRDNADLRCELPKLEKRLRAT 870
+ DS +T S AQ + ++ +E + KQ + ++ + L++++
Sbjct: 233 LSRRLRDSHETIASLRAQSPPVKYVIKTVEVESSKTKQALSES---QARNQHLQEQVAMQ 289
Query: 871 AERVKALESALKEAKENASRDRKR---YQQEVDR 901
+ +K +E L+ + + +R R + Y+ E++R
Sbjct: 290 RQVLKEMEQQLQSSHQLTARLRAQIAMYESELER 323
>gi|194294508 kinesin family member C3 isoform 3 [Homo sapiens]
Length = 687
Score = 222 bits (566), Expect = 1e-57
Identities = 134/329 (40%), Positives = 201/329 (61%), Gaps = 14/329 (4%)
Query: 8 NIKVMCRFRPLNESEVNRGDKYIA-KFQGEDTVVI----ASKPYAF--DRVFQSSTSQEQ 60
NI+V+ R RP+ + + + A F +D +I KP +F D+VF SQ+
Sbjct: 306 NIRVIARVRPVTKEDGEGPEATNAVTFDADDDSIIHLLHKGKPVSFELDKVFSPQASQQD 365
Query: 61 VYNDCAKKIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPEGMGIIPRIVQDIFNYIY 120
V+ + + +V ++G+N IFAYGQT +GKT+TMEG +P GI R +Q +F+ +
Sbjct: 366 VFQE-VQALVTSCIDGFNVCIFAYGQTGAGKTYTMEGTAENP---GINQRALQLLFSEVQ 421
Query: 121 SMDENLEFHIKVSYFEIYLDKIRDLLDVS---KTNLSVHEDKNRVPYVKGCTERFVCSPD 177
+ E+ I VS EIY + +RDLL K + + D + YV G TE V S D
Sbjct: 422 EKASDWEYTITVSAAEIYNEVLRDLLGKEPQEKLEIRLCPDGSGQLYVPGLTEFQVQSVD 481
Query: 178 EVMDTIDEGKSNRHVAVTNMNEHSSRSHSIFLINVKQENTQTEQKLSGKLYLVDLAGSEK 237
++ + G +NR TN+NEHSSRSH++ ++ V+ + T + +GKL LVDLAGSE+
Sbjct: 482 DINKVFEFGHTNRTTEFTNLNEHSSRSHALLIVTVRGVDCSTGLRTTGKLNLVDLAGSER 541
Query: 238 VSKTGAEGAVLDEAKNINKSLSALGNVISALAEGSTYVPYRDSKMTRILQDSLGGNCRTT 297
V K+GAEG+ L EA++INKSLSALG+VI+AL +VP+R+SK+T +LQDSL G+ +T
Sbjct: 542 VGKSGAEGSRLREAQHINKSLSALGDVIAALRSRQGHVPFRNSKLTYLLQDSLSGDSKTL 601
Query: 298 IVICCSPSSYNESETKSTLLFGQRAKTIK 326
+V+ SP N SET +L F +R ++++
Sbjct: 602 MVVQVSPVEKNTSETLYSLKFAERVRSVE 630
>gi|94536858 kinesin family member C3 isoform 1 [Homo sapiens]
Length = 833
Score = 222 bits (566), Expect = 1e-57
Identities = 134/329 (40%), Positives = 201/329 (61%), Gaps = 14/329 (4%)
Query: 8 NIKVMCRFRPLNESEVNRGDKYIA-KFQGEDTVVI----ASKPYAF--DRVFQSSTSQEQ 60
NI+V+ R RP+ + + + A F +D +I KP +F D+VF SQ+
Sbjct: 445 NIRVIARVRPVTKEDGEGPEATNAVTFDADDDSIIHLLHKGKPVSFELDKVFSPQASQQD 504
Query: 61 VYNDCAKKIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPEGMGIIPRIVQDIFNYIY 120
V+ + + +V ++G+N IFAYGQT +GKT+TMEG +P GI R +Q +F+ +
Sbjct: 505 VFQE-VQALVTSCIDGFNVCIFAYGQTGAGKTYTMEGTAENP---GINQRALQLLFSEVQ 560
Query: 121 SMDENLEFHIKVSYFEIYLDKIRDLLDVS---KTNLSVHEDKNRVPYVKGCTERFVCSPD 177
+ E+ I VS EIY + +RDLL K + + D + YV G TE V S D
Sbjct: 561 EKASDWEYTITVSAAEIYNEVLRDLLGKEPQEKLEIRLCPDGSGQLYVPGLTEFQVQSVD 620
Query: 178 EVMDTIDEGKSNRHVAVTNMNEHSSRSHSIFLINVKQENTQTEQKLSGKLYLVDLAGSEK 237
++ + G +NR TN+NEHSSRSH++ ++ V+ + T + +GKL LVDLAGSE+
Sbjct: 621 DINKVFEFGHTNRTTEFTNLNEHSSRSHALLIVTVRGVDCSTGLRTTGKLNLVDLAGSER 680
Query: 238 VSKTGAEGAVLDEAKNINKSLSALGNVISALAEGSTYVPYRDSKMTRILQDSLGGNCRTT 297
V K+GAEG+ L EA++INKSLSALG+VI+AL +VP+R+SK+T +LQDSL G+ +T
Sbjct: 681 VGKSGAEGSRLREAQHINKSLSALGDVIAALRSRQGHVPFRNSKLTYLLQDSLSGDSKTL 740
Query: 298 IVICCSPSSYNESETKSTLLFGQRAKTIK 326
+V+ SP N SET +L F +R ++++
Sbjct: 741 MVVQVSPVEKNTSETLYSLKFAERVRSVE 769
Score = 34.3 bits (77), Expect = 0.58
Identities = 43/214 (20%), Positives = 92/214 (42%), Gaps = 34/214 (15%)
Query: 714 KQISSLRDEVEAKAKLITDLQDQNQKMMLEQERLRVEHEKLKAT---------------- 757
+++S LR E+ TDL+ +M+E ERLR E + +A
Sbjct: 118 QEVSRLRSELGG-----TDLEKHRDLLMVENERLRQEMRRCEAELQELRTKPAGPCPGCE 172
Query: 758 -DQEKSRKLHELTVMQDRREQARQDLKGLEETVAKELQTLHNLRKLFVQDLATRVKKSAE 816
QE ++ +L+ +Q +++ L L V ++ L + LA + ++
Sbjct: 173 HSQESAQLRDKLSQLQLEMAESKGMLSELNLEVQQKTDRLAEVELRLKDCLAEKAQEEER 232
Query: 817 I-----DSDDTGGS-AAQKQKISFLENNLEQLTKVHKQLVRDNADLRCELPKLEKRLRAT 870
+ DS +T S AQ + ++ +E + KQ + ++ + L++++
Sbjct: 233 LSRRLRDSHETIASLRAQSPPVKYVIKTVEVESSKTKQALSES---QARNQHLQEQVAMQ 289
Query: 871 AERVKALESALKEAKENASRDRKR---YQQEVDR 901
+ +K +E L+ + + +R R + Y+ E++R
Sbjct: 290 RQVLKEMEQQLQSSHQLTARLRAQIAMYESELER 323
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.310 0.126 0.338
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 31,884,913
Number of Sequences: 37866
Number of extensions: 1423180
Number of successful extensions: 21920
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 544
Number of HSP's successfully gapped in prelim test: 1215
Number of HSP's that attempted gapping in prelim test: 7511
Number of HSP's gapped (non-prelim): 6786
length of query: 963
length of database: 18,247,518
effective HSP length: 112
effective length of query: 851
effective length of database: 14,006,526
effective search space: 11919553626
effective search space used: 11919553626
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.