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Search of human proteins with 4758630
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4758630 potassium voltage-gated channel KQT-like protein 3
[Homo sapiens]
(872 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4758630 potassium voltage-gated channel KQT-like protein 3 [H... 1760 0.0
gi|26051260 potassium voltage-gated channel KQT-like protein 2 i... 670 0.0
gi|26051262 potassium voltage-gated channel KQT-like protein 2 i... 665 0.0
gi|26051266 potassium voltage-gated channel KQT-like protein 2 i... 662 0.0
gi|26051264 potassium voltage-gated channel KQT-like protein 2 i... 660 0.0
gi|28373065 potassium voltage-gated channel, KQT-like subfamily,... 597 e-170
gi|236461719 potassium voltage-gated channel, KQT-like subfamily... 587 e-167
gi|236462079 potassium voltage-gated channel, KQT-like subfamily... 585 e-167
gi|236461942 potassium voltage-gated channel, KQT-like subfamily... 582 e-166
gi|26638655 potassium voltage-gated channel KQT-like protein 4 i... 571 e-162
gi|26638653 potassium voltage-gated channel KQT-like protein 4 i... 559 e-159
gi|26051268 potassium voltage-gated channel KQT-like protein 2 i... 462 e-130
gi|236462242 potassium voltage-gated channel, KQT-like subfamily... 442 e-124
gi|32479527 potassium voltage-gated channel, KQT-like subfamily,... 363 e-100
gi|32479525 potassium voltage-gated channel, KQT-like subfamily,... 342 1e-93
gi|119395748 potassium voltage-gated channel subfamily A member ... 86 2e-16
gi|4826782 potassium voltage-gated channel, shaker-related subfa... 83 1e-15
gi|88758576 Shaw-related voltage-gated potassium channel protein... 82 2e-15
gi|24497462 Shaw-related voltage-gated potassium channel protein... 82 2e-15
gi|24497464 Shaw-related voltage-gated potassium channel protein... 82 2e-15
gi|88758565 potassium voltage-gated channel, shaker-related subf... 80 6e-15
gi|21217561 Shaw-related voltage-gated potassium channel protein... 80 6e-15
gi|21217563 Shaw-related voltage-gated potassium channel protein... 80 6e-15
gi|24497458 Shaw-related voltage-gated potassium channel protein... 80 6e-15
gi|24497460 Shaw-related voltage-gated potassium channel protein... 80 1e-14
gi|4504817 potassium voltage-gated channel, shaker-related subfa... 79 2e-14
gi|4826784 potassium voltage-gated channel, Shab-related subfami... 79 2e-14
gi|4826786 Shaw-related voltage-gated potassium channel protein ... 78 3e-14
gi|163792201 Shaw-related voltage-gated potassium channel protei... 78 3e-14
gi|5031819 potassium voltage-gated channel, shaker-related subfa... 78 3e-14
>gi|4758630 potassium voltage-gated channel KQT-like protein 3 [Homo
sapiens]
Length = 872
Score = 1760 bits (4558), Expect = 0.0
Identities = 872/872 (100%), Positives = 872/872 (100%)
Query: 1 MGLKARRAAGAAGGGGDGGGGGGGAANPAGGDAAAAGDEERKVGLAPGDVEQVTLALGAG 60
MGLKARRAAGAAGGGGDGGGGGGGAANPAGGDAAAAGDEERKVGLAPGDVEQVTLALGAG
Sbjct: 1 MGLKARRAAGAAGGGGDGGGGGGGAANPAGGDAAAAGDEERKVGLAPGDVEQVTLALGAG 60
Query: 61 ADKDGTLLLEGGGRDEGQRRTPQGIGLLAKTPLSRPVKRNNAKYRRIQTLIYDALERPRG 120
ADKDGTLLLEGGGRDEGQRRTPQGIGLLAKTPLSRPVKRNNAKYRRIQTLIYDALERPRG
Sbjct: 61 ADKDGTLLLEGGGRDEGQRRTPQGIGLLAKTPLSRPVKRNNAKYRRIQTLIYDALERPRG 120
Query: 121 WALLYHALVFLIVLGCLILAVLTTFKEYETVSGDWLLLLETFAIFIFGAEFALRIWAAGC 180
WALLYHALVFLIVLGCLILAVLTTFKEYETVSGDWLLLLETFAIFIFGAEFALRIWAAGC
Sbjct: 121 WALLYHALVFLIVLGCLILAVLTTFKEYETVSGDWLLLLETFAIFIFGAEFALRIWAAGC 180
Query: 181 CCRYKGWRGRLKFARKPLCMLDIFVLIASVPVVAVGNQGNVLATSLRSLRFLQILRMLRM 240
CCRYKGWRGRLKFARKPLCMLDIFVLIASVPVVAVGNQGNVLATSLRSLRFLQILRMLRM
Sbjct: 181 CCRYKGWRGRLKFARKPLCMLDIFVLIASVPVVAVGNQGNVLATSLRSLRFLQILRMLRM 240
Query: 241 DRRGGTWKLLGSAICAHSKELITAWYIGFLTLILSSFLVYLVEKDVPEVDAQGEEMKEEF 300
DRRGGTWKLLGSAICAHSKELITAWYIGFLTLILSSFLVYLVEKDVPEVDAQGEEMKEEF
Sbjct: 241 DRRGGTWKLLGSAICAHSKELITAWYIGFLTLILSSFLVYLVEKDVPEVDAQGEEMKEEF 300
Query: 301 ETYADALWWGLITLATIGYGDKTPKTWEGRLIAATFSLIGVSFFALPAGILGSGLALKVQ 360
ETYADALWWGLITLATIGYGDKTPKTWEGRLIAATFSLIGVSFFALPAGILGSGLALKVQ
Sbjct: 301 ETYADALWWGLITLATIGYGDKTPKTWEGRLIAATFSLIGVSFFALPAGILGSGLALKVQ 360
Query: 361 EQHRQKHFEKRRKPAAELIQAAWRYYATNPNRIDLVATWRFYESVVSFPFFRKEQLEAAS 420
EQHRQKHFEKRRKPAAELIQAAWRYYATNPNRIDLVATWRFYESVVSFPFFRKEQLEAAS
Sbjct: 361 EQHRQKHFEKRRKPAAELIQAAWRYYATNPNRIDLVATWRFYESVVSFPFFRKEQLEAAS 420
Query: 421 SQKLGLLDRVRLSNPRGSNTKGKLFTPLNVDAIEESPSKEPKPVGLNNKERFRTAFRMKA 480
SQKLGLLDRVRLSNPRGSNTKGKLFTPLNVDAIEESPSKEPKPVGLNNKERFRTAFRMKA
Sbjct: 421 SQKLGLLDRVRLSNPRGSNTKGKLFTPLNVDAIEESPSKEPKPVGLNNKERFRTAFRMKA 480
Query: 481 YAFWQSSEDAGTGDPMAEDRGYGNDFPIEDMIPTLKAAIRAVRILQFRLYKKKFKETLRP 540
YAFWQSSEDAGTGDPMAEDRGYGNDFPIEDMIPTLKAAIRAVRILQFRLYKKKFKETLRP
Sbjct: 481 YAFWQSSEDAGTGDPMAEDRGYGNDFPIEDMIPTLKAAIRAVRILQFRLYKKKFKETLRP 540
Query: 541 YDVKDVIEQYSAGHLDMLSRIKYLQTRIDMIFTPGPPSTPKHKKSQKGSAFTFPSQQSPR 600
YDVKDVIEQYSAGHLDMLSRIKYLQTRIDMIFTPGPPSTPKHKKSQKGSAFTFPSQQSPR
Sbjct: 541 YDVKDVIEQYSAGHLDMLSRIKYLQTRIDMIFTPGPPSTPKHKKSQKGSAFTFPSQQSPR 600
Query: 601 NEPYVARPSTSEIEDQSMMGKFVKVERQVQDMGKKLDFLVDMHMQHMERLQVQVTEYYPT 660
NEPYVARPSTSEIEDQSMMGKFVKVERQVQDMGKKLDFLVDMHMQHMERLQVQVTEYYPT
Sbjct: 601 NEPYVARPSTSEIEDQSMMGKFVKVERQVQDMGKKLDFLVDMHMQHMERLQVQVTEYYPT 660
Query: 661 KGTSSPAEAEKKEDNRYSDLKTIICNYSETGPPEPPYSFHQVTIDKVSPYGFFAHDPVNL 720
KGTSSPAEAEKKEDNRYSDLKTIICNYSETGPPEPPYSFHQVTIDKVSPYGFFAHDPVNL
Sbjct: 661 KGTSSPAEAEKKEDNRYSDLKTIICNYSETGPPEPPYSFHQVTIDKVSPYGFFAHDPVNL 720
Query: 721 PRGGPSSGKVQATPPSSATTYVERPTVLPILTLLDSRVSCHSQADLQGPYSDRISPRQRR 780
PRGGPSSGKVQATPPSSATTYVERPTVLPILTLLDSRVSCHSQADLQGPYSDRISPRQRR
Sbjct: 721 PRGGPSSGKVQATPPSSATTYVERPTVLPILTLLDSRVSCHSQADLQGPYSDRISPRQRR 780
Query: 781 SITRDSDTPLSLMSVNHEELERSPSGFSISQDRDDYVFGPNGGSSWMREKRYLAEGETDT 840
SITRDSDTPLSLMSVNHEELERSPSGFSISQDRDDYVFGPNGGSSWMREKRYLAEGETDT
Sbjct: 781 SITRDSDTPLSLMSVNHEELERSPSGFSISQDRDDYVFGPNGGSSWMREKRYLAEGETDT 840
Query: 841 DTDPFTPSGSMPLSSTGDGISDSVWTPSNKPI 872
DTDPFTPSGSMPLSSTGDGISDSVWTPSNKPI
Sbjct: 841 DTDPFTPSGSMPLSSTGDGISDSVWTPSNKPI 872
>gi|26051260 potassium voltage-gated channel KQT-like protein 2
isoform c [Homo sapiens]
Length = 844
Score = 670 bits (1728), Expect = 0.0
Identities = 419/897 (46%), Positives = 530/897 (59%), Gaps = 121/897 (13%)
Query: 39 EERKVGLAPGDVEQVTLALG-AGAD-------KDGTLLLEGGGRDEGQRRTPQGIGLLAK 90
+ R G+ PG + L +G G D +DG LL+ G P+ +L+K
Sbjct: 4 KSRNGGVYPGPSGEKKLKVGFVGLDPGAPDSTRDGALLIAGS-------EAPKRGSILSK 56
Query: 91 -----TPLSRPVKRNNAKYRRIQTLIYDALERPRGWALLYHALVFLIVLGCLILAVLTTF 145
+P KRN A YR++Q +Y+ LERPRGWA +YHA VFL+V CL+L+V +T
Sbjct: 57 PRAGGAGAGKPPKRN-AFYRKLQNFLYNVLERPRGWAFIYHAYVFLLVFSCLVLSVFSTI 115
Query: 146 KEYETVSGDWLLLLETFAIFIFGAEFALRIWAAGCCCRYKGWRGRLKFARKPLCMLDIFV 205
KEYE S L +LE I +FG E+ +RIWAAGCCCRY+GWRGRLKFARKP C++DI V
Sbjct: 116 KEYEKSSEGALYILEIVTIVVFGVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMV 175
Query: 206 LIASVPVVAVGNQGNVLATS-LRSLRFLQILRMLRMDRRGGTWKLLGSAICAHSKELITA 264
LIAS+ V+A G+QGNV ATS LRSLRFLQILRM+RMDRRGGTWKLLGS + AHSKEL+TA
Sbjct: 176 LIASIAVLAAGSQGNVFATSALRSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELVTA 235
Query: 265 WYIGFLTLILSSFLVYLVEKDVPEVDAQGEEMKEEFETYADALWWGLITLATIGYGDKTP 324
WYIGFL LIL+SFLVYL EK GE + F+TYADALWWGLITL TIGYGDK P
Sbjct: 236 WYIGFLCLILASFLVYLAEK--------GEN--DHFDTYADALWWGLITLTTIGYGDKYP 285
Query: 325 KTWEGRLIAATFSLIGVSFFALPAGILGSGLALKVQEQHRQKHFEKRRKPAAELIQAAWR 384
+TW GRL+AATF+LIGVSFFALPAGILGSG ALKVQEQHRQKHFEKRR PAA LIQ+AWR
Sbjct: 286 QTWNGRLLAATFTLIGVSFFALPAGILGSGFALKVQEQHRQKHFEKRRNPAAGLIQSAWR 345
Query: 385 YYATNPNRIDLVATWRFYESVVSFPFFR----KEQL--------------------EAAS 420
+YATN +R DL +TW++YE V+ P +R QL E +
Sbjct: 346 FYATNLSRTDLHSTWQYYERTVTVPMYRLIPPLNQLELLRNLKSKSGLAFRKDPPPEPSP 405
Query: 421 SQKLGLLDRVRLSNPRGSNTKGK--------LFTPLNVDAIEESPSKEPKPVGLNNKERF 472
SQK+ L DRV S+PRG KGK +P ++E+SPSK PK ++ R
Sbjct: 406 SQKVSLKDRV-FSSPRGVAAKGKGSPQAQTVRRSPSADQSLEDSPSKVPKSWSFGDRSRA 464
Query: 473 RTAFRMKAYAFWQSSEDAG-TGDPMAEDRGYGNDFPIEDMIPTLKAAIRAVRILQFRLYK 531
R AFR+K A Q+SE+A G+ + +D+ +F ED+ P LK +IRAV +++F + K
Sbjct: 465 RQAFRIKGAASRQNSEEASLPGEDIVDDKSCPCEFVTEDLTPGLKVSIRAVCVMRFLVSK 524
Query: 532 KKFKETLRPYDVKDVIEQYSAGHLDMLSRIKYLQTRIDMIFTPGPPSTPKHKKSQKGSAF 591
+KFKE+LRPYDV DVIEQYSAGHLDMLSRIK LQ+R+D I GP T K + KG
Sbjct: 525 RKFKESLRPYDVMDVIEQYSAGHLDMLSRIKSLQSRVDQIVGRGPAITDKDR--TKG--- 579
Query: 592 TFPSQQSPRNEPYVARPSTSEI-EDQSMMGKFVKVERQVQDMGKKLDFLVDMHMQHMERL 650
P+ +E+ ED SMMG+ KVE+QV M KKLDFLV+++MQ M
Sbjct: 580 ----------------PAEAELPEDPSMMGRLGKVEKQVLSMEKKLDFLVNIYMQRMGIP 623
Query: 651 QVQVTEYYPTKGTSSPAEAEKKED-----NRYSDLKTIICNYSETG-------PPEPPYS 698
+ Y+ K ED +R+ + I+ + S TG P PP
Sbjct: 624 PTETEAYFGAKEPEPAPPYHSPEDSREHVDRHGCIVKIVRSSSSTGQKNFSAPPAAPPVQ 683
Query: 699 FHQVTIDKVSPYGFFAHDPVNLPRGGPSSGKVQATPPSSATTYVERPTVLPILTLLDSRV 758
T + P + PR G T P + R P S
Sbjct: 684 CPPST----------SWQPQSHPRQG------HGTSPVGDHGSLVRIPPPPAHERSLSAY 727
Query: 759 SCHSQADLQG-PYSDRISPRQRRSITRDSDTPLSLMSVNHEELERSPSGFSISQDRDDYV 817
++A ++ D R RDSDT +S+ SV+HEELERS SGFSISQ +++
Sbjct: 728 GGGNRASMEFLRQEDTPGCRPPEGNLRDSDTSISIPSVDHEELERSFSGFSISQSKENLD 787
Query: 818 FGPN---GGSSWMREKRYLAEGETDTDTDPFTPSGSMPLSSTGDG-ISDSVWTPSNK 870
+ + + + Y+AEGE+DTD+D TP G P S+TG+G D W K
Sbjct: 788 ALNSCYAAVAPCAKVRPYIAEGESDTDSDLCTPCGPPPRSATGEGPFGDVGWAGPRK 844
>gi|26051262 potassium voltage-gated channel KQT-like protein 2
isoform b [Homo sapiens]
Length = 854
Score = 665 bits (1717), Expect = 0.0
Identities = 419/907 (46%), Positives = 530/907 (58%), Gaps = 131/907 (14%)
Query: 39 EERKVGLAPGDVEQVTLALG-AGAD-------KDGTLLLEGGGRDEGQRRTPQGIGLLAK 90
+ R G+ PG + L +G G D +DG LL+ G P+ +L+K
Sbjct: 4 KSRNGGVYPGPSGEKKLKVGFVGLDPGAPDSTRDGALLIAGS-------EAPKRGSILSK 56
Query: 91 -----TPLSRPVKRNNAKYRRIQTLIYDALERPRGWALLYHALVFLIVLGCLILAVLTTF 145
+P KRN A YR++Q +Y+ LERPRGWA +YHA VFL+V CL+L+V +T
Sbjct: 57 PRAGGAGAGKPPKRN-AFYRKLQNFLYNVLERPRGWAFIYHAYVFLLVFSCLVLSVFSTI 115
Query: 146 KEYETVSGDWLLLLETFAIFIFGAEFALRIWAAGCCCRYKGWRGRLKFARKPLCMLDIFV 205
KEYE S L +LE I +FG E+ +RIWAAGCCCRY+GWRGRLKFARKP C++DI V
Sbjct: 116 KEYEKSSEGALYILEIVTIVVFGVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMV 175
Query: 206 LIASVPVVAVGNQGNVLATS-LRSLRFLQILRMLRMDRRGGTWKLLGSAICAHSKELITA 264
LIAS+ V+A G+QGNV ATS LRSLRFLQILRM+RMDRRGGTWKLLGS + AHSKEL+TA
Sbjct: 176 LIASIAVLAAGSQGNVFATSALRSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELVTA 235
Query: 265 WYIGFLTLILSSFLVYLVEKDVPEVDAQGEEMKEEFETYADALWWGLITLATIGYGDKTP 324
WYIGFL LIL+SFLVYL EK GE + F+TYADALWWGLITL TIGYGDK P
Sbjct: 236 WYIGFLCLILASFLVYLAEK--------GEN--DHFDTYADALWWGLITLTTIGYGDKYP 285
Query: 325 KTWEGRLIAATFSLIGVSFFALPAGILGSGLALKVQEQHRQKHFEKRRKPAAELIQAAWR 384
+TW GRL+AATF+LIGVSFFALPAGILGSG ALKVQEQHRQKHFEKRR PAA LIQ+AWR
Sbjct: 286 QTWNGRLLAATFTLIGVSFFALPAGILGSGFALKVQEQHRQKHFEKRRNPAAGLIQSAWR 345
Query: 385 YYATNPNRIDLVATWRFYESVVSFPF---------------------------------F 411
+YATN +R DL +TW++YE V+ P F
Sbjct: 346 FYATNLSRTDLHSTWQYYERTVTVPMYSSQTQTYGASRLIPPLNQLELLRNLKSKSGLAF 405
Query: 412 RKEQL-EAASSQKLGLLDRVRLSNPRGSNTKGK--------LFTPLNVDAIEESPSKEPK 462
RK+ E + SQK+ L DRV S+PRG KGK +P ++E+SPSK PK
Sbjct: 406 RKDPPPEPSPSQKVSLKDRV-FSSPRGVAAKGKGSPQAQTVRRSPSADQSLEDSPSKVPK 464
Query: 463 PVGLNNKERFRTAFRMKAYAFWQSSEDAGT-GDPMAEDRGYGNDFPIEDMIPTLKAAIRA 521
++ R R AFR+K A Q+SE+A G+ + +D+ +F ED+ P LK +IRA
Sbjct: 465 SWSFGDRSRARQAFRIKGAASRQNSEEASLPGEDIVDDKSCPCEFVTEDLTPGLKVSIRA 524
Query: 522 VRILQFRLYKKKFKETLRPYDVKDVIEQYSAGHLDMLSRIKYLQTRIDMIFTPGPPSTPK 581
V +++F + K+KFKE+LRPYDV DVIEQYSAGHLDMLSRIK LQ+R+D I GP T K
Sbjct: 525 VCVMRFLVSKRKFKESLRPYDVMDVIEQYSAGHLDMLSRIKSLQSRVDQIVGRGPAITDK 584
Query: 582 HKKSQKGSAFTFPSQQSPRNEPYVARPSTSEI-EDQSMMGKFVKVERQVQDMGKKLDFLV 640
+ KG P+ +E+ ED SMMG+ KVE+QV M KKLDFLV
Sbjct: 585 DR--TKG-------------------PAEAELPEDPSMMGRLGKVEKQVLSMEKKLDFLV 623
Query: 641 DMHMQHMERLQVQVTEYYPTKGTSSPAEAEKKED-----NRYSDLKTIICNYSETG---- 691
+++MQ M + Y+ K ED +R+ + I+ + S TG
Sbjct: 624 NIYMQRMGIPPTETEAYFGAKEPEPAPPYHSPEDSREHVDRHGCIVKIVRSSSSTGQKNF 683
Query: 692 ---PPEPPYSFHQVTIDKVSPYGFFAHDPVNLPRGGPSSGKVQATPPSSATTYVERPTVL 748
P PP T + P + PR G T P + R
Sbjct: 684 SAPPAAPPVQCPPST----------SWQPQSHPRQG------HGTSPVGDHGSLVRIPPP 727
Query: 749 PILTLLDSRVSCHSQADLQG-PYSDRISPRQRRSITRDSDTPLSLMSVNHEELERSPSGF 807
P S ++A ++ D R RDSDT +S+ SV+HEELERS SGF
Sbjct: 728 PAHERSLSAYGGGNRASMEFLRQEDTPGCRPPEGNLRDSDTSISIPSVDHEELERSFSGF 787
Query: 808 SISQDRDDYVFGPN---GGSSWMREKRYLAEGETDTDTDPFTPSGSMPLSSTGDG-ISDS 863
SISQ +++ + + + + Y+AEGE+DTD+D TP G P S+TG+G D
Sbjct: 788 SISQSKENLDALNSCYAAVAPCAKVRPYIAEGESDTDSDLCTPCGPPPRSATGEGPFGDV 847
Query: 864 VWTPSNK 870
W K
Sbjct: 848 GWAGPRK 854
>gi|26051266 potassium voltage-gated channel KQT-like protein 2
isoform d [Homo sapiens]
Length = 841
Score = 662 bits (1709), Expect = 0.0
Identities = 409/893 (45%), Positives = 525/893 (58%), Gaps = 116/893 (12%)
Query: 39 EERKVGLAPGDVEQVTLALG-AGAD-------KDGTLLLEGGGRDEGQRRTPQGIGLLAK 90
+ R G+ PG + L +G G D +DG LL+ G P+ +L+K
Sbjct: 4 KSRNGGVYPGPSGEKKLKVGFVGLDPGAPDSTRDGALLIAGS-------EAPKRGSILSK 56
Query: 91 -----TPLSRPVKRNNAKYRRIQTLIYDALERPRGWALLYHALVFLIVLGCLILAVLTTF 145
+P KRN A YR++Q +Y+ LERPRGWA +YHA VFL+V CL+L+V +T
Sbjct: 57 PRAGGAGAGKPPKRN-AFYRKLQNFLYNVLERPRGWAFIYHAYVFLLVFSCLVLSVFSTI 115
Query: 146 KEYETVSGDWLLLLETFAIFIFGAEFALRIWAAGCCCRYKGWRGRLKFARKPLCMLDIFV 205
KEYE S L +LE I +FG E+ +RIWAAGCCCRY+GWRGRLKFARKP C++DI V
Sbjct: 116 KEYEKSSEGALYILEIVTIVVFGVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMV 175
Query: 206 LIASVPVVAVGNQGNVLATS-LRSLRFLQILRMLRMDRRGGTWKLLGSAICAHSKELITA 264
LIAS+ V+A G+QGNV ATS LRSLRFLQILRM+RMDRRGGTWKLLGS + AHSKEL+TA
Sbjct: 176 LIASIAVLAAGSQGNVFATSALRSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELVTA 235
Query: 265 WYIGFLTLILSSFLVYLVEKDVPEVDAQGEEMKEEFETYADALWWGLITLATIGYGDKTP 324
WYIGFL LIL+SFLVYL EK GE + F+TYADALWWGLITL TIGYGDK P
Sbjct: 236 WYIGFLCLILASFLVYLAEK--------GEN--DHFDTYADALWWGLITLTTIGYGDKYP 285
Query: 325 KTWEGRLIAATFSLIGVSFFALPAGILGSGLALKVQEQHRQKHFEKRRKPAAELIQAAWR 384
+TW GRL+AATF+LIGVSFFALPAGILGSG ALKVQEQHRQKHFEKRR PAA LIQ+AWR
Sbjct: 286 QTWNGRLLAATFTLIGVSFFALPAGILGSGFALKVQEQHRQKHFEKRRNPAAGLIQSAWR 345
Query: 385 YYATNPNRIDLVATWRFYESVVSFPFFRKEQLEAASSQKLGLLDRVRL------------ 432
+YATN +R DL +TW++YE V+ P + + +S+ + L+++ L
Sbjct: 346 FYATNLSRTDLHSTWQYYERTVTVPMYSSQTQTYGASRLIPPLNQLELLRNLKSKSGLAF 405
Query: 433 ---------SNPRGSNTKGK--------LFTPLNVDAIEESPSKEPKPVGLNNKERFRTA 475
+PRG KGK +P ++E+SPSK PK ++ R R A
Sbjct: 406 RKDPPPEPSPSPRGVAAKGKGSPQAQTVRRSPSADQSLEDSPSKVPKSWSFGDRSRARQA 465
Query: 476 FRMKAYAFWQSSEDAGTGDPMAEDRGYGNDFPIEDMIPTLKAAIRAVRILQFRLYKKKFK 535
FR+K A Q+SE + G+ + +D+ +F ED+ P LK +IRAV +++F + K+KFK
Sbjct: 466 FRIKGAASRQNSEASLPGEDIVDDKSCPCEFVTEDLTPGLKVSIRAVCVMRFLVSKRKFK 525
Query: 536 ETLRPYDVKDVIEQYSAGHLDMLSRIKYLQTRIDMIFTPGPPSTPKHKKSQKGSAFTFPS 595
E+LRPYDV DVIEQYSAGHLDMLSRIK LQ+R+D I GP T K + KG
Sbjct: 526 ESLRPYDVMDVIEQYSAGHLDMLSRIKSLQSRVDQIVGRGPAITDKDR--TKG------- 576
Query: 596 QQSPRNEPYVARPSTSEI-EDQSMMGKFVKVERQVQDMGKKLDFLVDMHMQHMERLQVQV 654
P+ +E+ ED SMMG+ KVE+QV M KKLDFLV+++MQ M +
Sbjct: 577 ------------PAEAELPEDPSMMGRLGKVEKQVLSMEKKLDFLVNIYMQRMGIPPTET 624
Query: 655 TEYYPTKGTSSPAEAEKKED-----NRYSDLKTIICNYSETG-------PPEPPYSFHQV 702
Y+ K ED +R+ + I+ + S TG P PP
Sbjct: 625 EAYFGAKEPEPAPPYHSPEDSREHVDRHGCIVKIVRSSSSTGQKNFSAPPAAPPVQCPPS 684
Query: 703 TIDKVSPYGFFAHDPVNLPRGGPSSGKVQATPPSSATTYVERPTVLPILTLLDSRVSCHS 762
T + P + PR G T P + R P S +
Sbjct: 685 T----------SWQPQSHPRQG------HGTSPVGDHGSLVRIPPPPAHERSLSAYGGGN 728
Query: 763 QADLQG-PYSDRISPRQRRSITRDSDTPLSLMSVNHEELERSPSGFSISQDRDDYVFGPN 821
+A ++ D R RDSDT +S+ SV+HEELERS SGFSISQ +++ +
Sbjct: 729 RASMEFLRQEDTPGCRPPEGNLRDSDTSISIPSVDHEELERSFSGFSISQSKENLDALNS 788
Query: 822 ---GGSSWMREKRYLAEGETDTDTDPFTPSGSMPLSSTGDG-ISDSVWTPSNK 870
+ + + Y+AEGE+DTD+D TP G P S+TG+G D W K
Sbjct: 789 CYAAVAPCAKVRPYIAEGESDTDSDLCTPCGPPPRSATGEGPFGDVGWAGPRK 841
>gi|26051264 potassium voltage-gated channel KQT-like protein 2
isoform a [Homo sapiens]
Length = 872
Score = 660 bits (1702), Expect = 0.0
Identities = 419/925 (45%), Positives = 530/925 (57%), Gaps = 149/925 (16%)
Query: 39 EERKVGLAPGDVEQVTLALG-AGAD-------KDGTLLLEGGGRDEGQRRTPQGIGLLAK 90
+ R G+ PG + L +G G D +DG LL+ G P+ +L+K
Sbjct: 4 KSRNGGVYPGPSGEKKLKVGFVGLDPGAPDSTRDGALLIAGS-------EAPKRGSILSK 56
Query: 91 -----TPLSRPVKRNNAKYRRIQTLIYDALERPRGWALLYHALVFLIVLGCLILAVLTTF 145
+P KRN A YR++Q +Y+ LERPRGWA +YHA VFL+V CL+L+V +T
Sbjct: 57 PRAGGAGAGKPPKRN-AFYRKLQNFLYNVLERPRGWAFIYHAYVFLLVFSCLVLSVFSTI 115
Query: 146 KEYETVSGDWLLLLETFAIFIFGAEFALRIWAAGCCCRYKGWRGRLKFARKPLCMLDIFV 205
KEYE S L +LE I +FG E+ +RIWAAGCCCRY+GWRGRLKFARKP C++DI V
Sbjct: 116 KEYEKSSEGALYILEIVTIVVFGVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMV 175
Query: 206 LIASVPVVAVGNQGNVLATS-LRSLRFLQILRMLRMDRRGGTWKLLGSAICAHSKELITA 264
LIAS+ V+A G+QGNV ATS LRSLRFLQILRM+RMDRRGGTWKLLGS + AHSKEL+TA
Sbjct: 176 LIASIAVLAAGSQGNVFATSALRSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELVTA 235
Query: 265 WYIGFLTLILSSFLVYLVEKDVPEVDAQGEEMKEEFETYADALWWGLITLATIGYGDKTP 324
WYIGFL LIL+SFLVYL EK GE + F+TYADALWWGLITL TIGYGDK P
Sbjct: 236 WYIGFLCLILASFLVYLAEK--------GEN--DHFDTYADALWWGLITLTTIGYGDKYP 285
Query: 325 KTWEGRLIAATFSLIGVSFFALPAGILGSGLALKVQEQHRQKHFEKRRKPAAELIQAAWR 384
+TW GRL+AATF+LIGVSFFALPAGILGSG ALKVQEQHRQKHFEKRR PAA LIQ+AWR
Sbjct: 286 QTWNGRLLAATFTLIGVSFFALPAGILGSGFALKVQEQHRQKHFEKRRNPAAGLIQSAWR 345
Query: 385 YYATNPNRIDLVATWRFYESVVSFPFFRKE--------------QLE------------- 417
+YATN +R DL +TW++YE V+ P + + QLE
Sbjct: 346 FYATNLSRTDLHSTWQYYERTVTVPMYSSQTQTYGASRLIPPLNQLELLRNLKSKSGLAF 405
Query: 418 -------------------------AASSQKLGLLDRVRLSNPRGSNTKGK--------L 444
SSQK+ L DRV S+PRG KGK
Sbjct: 406 RKDPPPEPSPSKGSPCRGPLCGCCPGRSSQKVSLKDRV-FSSPRGVAAKGKGSPQAQTVR 464
Query: 445 FTPLNVDAIEESPSKEPKPVGLNNKERFRTAFRMKAYAFWQSSEDAG-TGDPMAEDRGYG 503
+P ++E+SPSK PK ++ R R AFR+K A Q+SE+A G+ + +D+
Sbjct: 465 RSPSADQSLEDSPSKVPKSWSFGDRSRARQAFRIKGAASRQNSEEASLPGEDIVDDKSCP 524
Query: 504 NDFPIEDMIPTLKAAIRAVRILQFRLYKKKFKETLRPYDVKDVIEQYSAGHLDMLSRIKY 563
+F ED+ P LK +IRAV +++F + K+KFKE+LRPYDV DVIEQYSAGHLDMLSRIK
Sbjct: 525 CEFVTEDLTPGLKVSIRAVCVMRFLVSKRKFKESLRPYDVMDVIEQYSAGHLDMLSRIKS 584
Query: 564 LQTRIDMIFTPGPPSTPKHKKSQKGSAFTFPSQQSPRNEPYVARPSTSEI-EDQSMMGKF 622
LQ+R+D I GP T K + KG P+ +E+ ED SMMG+
Sbjct: 585 LQSRVDQIVGRGPAITDKDR--TKG-------------------PAEAELPEDPSMMGRL 623
Query: 623 VKVERQVQDMGKKLDFLVDMHMQHMERLQVQVTEYYPTKGTSSPAEAEKKED-----NRY 677
KVE+QV M KKLDFLV+++MQ M + Y+ K ED +R+
Sbjct: 624 GKVEKQVLSMEKKLDFLVNIYMQRMGIPPTETEAYFGAKEPEPAPPYHSPEDSREHVDRH 683
Query: 678 SDLKTIICNYSETG-------PPEPPYSFHQVTIDKVSPYGFFAHDPVNLPRGGPSSGKV 730
+ I+ + S TG P PP T + P + PR G
Sbjct: 684 GCIVKIVRSSSSTGQKNFSAPPAAPPVQCPPST----------SWQPQSHPRQG------ 727
Query: 731 QATPPSSATTYVERPTVLPILTLLDSRVSCHSQADLQG-PYSDRISPRQRRSITRDSDTP 789
T P + R P S ++A ++ D R RDSDT
Sbjct: 728 HGTSPVGDHGSLVRIPPPPAHERSLSAYGGGNRASMEFLRQEDTPGCRPPEGNLRDSDTS 787
Query: 790 LSLMSVNHEELERSPSGFSISQDRDDYVFGPN---GGSSWMREKRYLAEGETDTDTDPFT 846
+S+ SV+HEELERS SGFSISQ +++ + + + + Y+AEGE+DTD+D T
Sbjct: 788 ISIPSVDHEELERSFSGFSISQSKENLDALNSCYAAVAPCAKVRPYIAEGESDTDSDLCT 847
Query: 847 PSGSMPLSSTGDG-ISDSVWTPSNK 870
P G P S+TG+G D W K
Sbjct: 848 PCGPPPRSATGEGPFGDVGWAGPRK 872
>gi|28373065 potassium voltage-gated channel, KQT-like subfamily,
member 5 isoform 1 [Homo sapiens]
Length = 932
Score = 597 bits (1539), Expect = e-170
Identities = 343/665 (51%), Positives = 429/665 (64%), Gaps = 67/665 (10%)
Query: 14 GGGDGGGGG-----GGAANPAGGDAAAAGDEERKVGLAPGDVEQVTLALGAGADKDGTLL 68
GG +GG G G AA AGG +G ++ + G L A A DG LL
Sbjct: 7 GGEEGGAAGLWVKSGAAAAAAGGGRLGSGMKDVESGRGR------VLLNSAAARGDGLLL 60
Query: 69 L--------EGGGRDEGQRRTPQG--IGLLAKTPLSRPVK---RNNAKYRRIQTLIYDAL 115
L GGG RR QG + LL K PLS R N KYRR+Q +Y+ L
Sbjct: 61 LGTRAATLGGGGGGLRESRRGKQGARMSLLGK-PLSYTSSQSCRRNVKYRRVQNYLYNVL 119
Query: 116 ERPRGWALLYHALVFLIVLGCLILAVLTTFKEYETVSGDWLLLLETFAIFIFGAEFALRI 175
ERPRGWA +YHA VFL+V GCLIL+V +T E+ ++ LL+LE I +FG EF +RI
Sbjct: 120 ERPRGWAFIYHAFVFLLVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVFGLEFIIRI 179
Query: 176 WAAGCCCRYKGWRGRLKFARKPLCMLDIFVLIASVPVVAVGNQGNVLATS-LRSLRFLQI 234
W+AGCCCRY+GW+GRL+FARKP C++D VLIAS+ VV+ QGN+ ATS LRSLRFLQI
Sbjct: 180 WSAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSALRSLRFLQI 239
Query: 235 LRMLRMDRRGGTWKLLGSAICAHSKELITAWYIGFLTLILSSFLVYLVEKDVPEVDAQGE 294
LRM+RMDRRGGTWKLLGS + AHSKELITAWYIGFL LI SSFLVYLVEKD
Sbjct: 240 LRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDA-------- 291
Query: 295 EMKEEFETYADALWWGLITLATIGYGDKTPKTWEGRLIAATFSLIGVSFFALPAGILGSG 354
+EF TYADALWWG ITL TIGYGDKTP TW GRL++A F+L+G+SFFALPAGILGSG
Sbjct: 292 --NKEFSTYADALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSG 349
Query: 355 LALKVQEQHRQKHFEKRRKPAAELIQAAWRYYATNPNRIDLVATWR-FYESVVSFPFFRK 413
ALKVQEQHRQKHFEKRR PAA LIQ WR YA + + +ATW+ +++ + +K
Sbjct: 350 FALKVQEQHRQKHFEKRRNPAANLIQCVWRSYAADEKSVS-IATWKPHLKALHTCSPTKK 408
Query: 414 EQLEAASSQKLGLLDRVRLSNPRGSNTK------GKLFTPLNVDAIEESPSKEPKPVGLN 467
EQ EA+SSQKL +RVR+++PRG + K G +P E SP+K K N
Sbjct: 409 EQGEASSSQKLSFKERVRMASPRGQSIKSRQASVGDRRSPSTDITAEGSPTKVQKSWSFN 468
Query: 468 NKERFRTAFRMKAYAFWQSSEDAGTG---DPMAEDRGYGNDFPIEDMIPTLKAAIRAVRI 524
++ RFR + R+K+ + + DA T D + +++G D +ED+ P LK IRA+RI
Sbjct: 469 DRTRFRPSLRLKS-SQPKPVIDADTALGTDDVYDEKGCQCDVSVEDLTPPLKTVIRAIRI 527
Query: 525 LQFRLYKKKFKETLRPYDVKDVIEQYSAGHLDMLSRIKYLQTRIDMIFTPGPPSTPKHKK 584
++F + K+KFKETLRPYDVKDVIEQYSAGHLDML RIK LQTR+D I G ++ K +
Sbjct: 528 MKFHVAKRKFKETLRPYDVKDVIEQYSAGHLDMLCRIKSLQTRVDQILGKGQITSDKKSR 587
Query: 585 SQKGSAFTFPSQQSPRNEPYVARPSTSEIEDQSMMGKFVKVERQVQDMGKKLDFLVDMHM 644
E A T+ +D SM+G+ VKVE+QVQ + KLD L+D++
Sbjct: 588 -----------------EKITAEHETT--DDLSMLGRVVKVEKQVQSIESKLDCLLDIYQ 628
Query: 645 QHMER 649
Q + +
Sbjct: 629 QVLRK 633
>gi|236461719 potassium voltage-gated channel, KQT-like subfamily,
member 5 isoform 2 [Homo sapiens]
Length = 923
Score = 587 bits (1512), Expect = e-167
Identities = 337/664 (50%), Positives = 421/664 (63%), Gaps = 74/664 (11%)
Query: 14 GGGDGGGGG-----GGAANPAGGDAAAAGDEERKVGLAPGDVEQVTLALGAGADKDGTLL 68
GG +GG G G AA AGG +G ++ + G L A A DG LL
Sbjct: 7 GGEEGGAAGLWVKSGAAAAAAGGGRLGSGMKDVESGRGR------VLLNSAAARGDGLLL 60
Query: 69 L--------EGGGRDEGQRRTPQG--IGLLAKTPLSRPVK---RNNAKYRRIQTLIYDAL 115
L GGG RR QG + LL K PLS R N KYRR+Q +Y+ L
Sbjct: 61 LGTRAATLGGGGGGLRESRRGKQGARMSLLGK-PLSYTSSQSCRRNVKYRRVQNYLYNVL 119
Query: 116 ERPRGWALLYHALVFLIVLGCLILAVLTTFKEYETVSGDWLLLLETFAIFIFGAEFALRI 175
ERPRGWA +YHA VFL+V GCLIL+V +T E+ ++ LL+LE I +FG EF +RI
Sbjct: 120 ERPRGWAFIYHAFVFLLVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVFGLEFIIRI 179
Query: 176 WAAGCCCRYKGWRGRLKFARKPLCMLDIFVLIASVPVVAVGNQGNVLATS-LRSLRFLQI 234
W+AGCCCRY+GW+GRL+FARKP C++D VLIAS+ VV+ QGN+ ATS LRSLRFLQI
Sbjct: 180 WSAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSALRSLRFLQI 239
Query: 235 LRMLRMDRRGGTWKLLGSAICAHSKELITAWYIGFLTLILSSFLVYLVEKDVPEVDAQGE 294
LRM+RMDRRGGTWKLLGS + AHSKELITAWYIGFL LI SSFLVYLVEKD
Sbjct: 240 LRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDA-------- 291
Query: 295 EMKEEFETYADALWWGLITLATIGYGDKTPKTWEGRLIAATFSLIGVSFFALPAGILGSG 354
+EF TYADALWWG ITL TIGYGDKTP TW GRL++A F+L+G+SFFALPAGILGSG
Sbjct: 292 --NKEFSTYADALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSG 349
Query: 355 LALKVQEQHRQKHFEKRRKPAAELIQAAWRYYATNPNRIDLVATWRFYESVVSFPFFRKE 414
ALKVQEQHRQKHFEKRR PAA LIQ WR YA + + +ATW+ P +
Sbjct: 350 FALKVQEQHRQKHFEKRRNPAANLIQCVWRSYAADEKSVS-IATWK--------PHLKAL 400
Query: 415 QLEAASSQKLGLLDRVRLSNPRGSNTK------GKLFTPLNVDAIEESPSKEPKPVGLNN 468
+ ++QKL +RVR+++PRG + K G +P E SP+K K N+
Sbjct: 401 HTCSPTNQKLSFKERVRMASPRGQSIKSRQASVGDRRSPSTDITAEGSPTKVQKSWSFND 460
Query: 469 KERFRTAFRMKAYAFWQSSEDAGTG---DPMAEDRGYGNDFPIEDMIPTLKAAIRAVRIL 525
+ RFR + R+K+ + + DA T D + +++G D +ED+ P LK IRA+RI+
Sbjct: 461 RTRFRPSLRLKS-SQPKPVIDADTALGTDDVYDEKGCQCDVSVEDLTPPLKTVIRAIRIM 519
Query: 526 QFRLYKKKFKETLRPYDVKDVIEQYSAGHLDMLSRIKYLQTRIDMIFTPGPPSTPKHKKS 585
+F + K+KFKETLRPYDVKDVIEQYSAGHLDML RIK LQTR+D I G ++ K +
Sbjct: 520 KFHVAKRKFKETLRPYDVKDVIEQYSAGHLDMLCRIKSLQTRVDQILGKGQITSDKKSR- 578
Query: 586 QKGSAFTFPSQQSPRNEPYVARPSTSEIEDQSMMGKFVKVERQVQDMGKKLDFLVDMHMQ 645
E A T+ +D SM+G+ VKVE+QVQ + KLD L+D++ Q
Sbjct: 579 ----------------EKITAEHETT--DDLSMLGRVVKVEKQVQSIESKLDCLLDIYQQ 620
Query: 646 HMER 649
+ +
Sbjct: 621 VLRK 624
>gi|236462079 potassium voltage-gated channel, KQT-like subfamily,
member 5 isoform 4 [Homo sapiens]
Length = 951
Score = 585 bits (1509), Expect = e-167
Identities = 343/684 (50%), Positives = 429/684 (62%), Gaps = 86/684 (12%)
Query: 14 GGGDGGGGG-----GGAANPAGGDAAAAGDEERKVGLAPGDVEQVTLALGAGADKDGTLL 68
GG +GG G G AA AGG +G ++ + G L A A DG LL
Sbjct: 7 GGEEGGAAGLWVKSGAAAAAAGGGRLGSGMKDVESGRGR------VLLNSAAARGDGLLL 60
Query: 69 L--------EGGGRDEGQRRTPQG--IGLLAKTPLSRPVK---RNNAKYRRIQTLIYDAL 115
L GGG RR QG + LL K PLS R N KYRR+Q +Y+ L
Sbjct: 61 LGTRAATLGGGGGGLRESRRGKQGARMSLLGK-PLSYTSSQSCRRNVKYRRVQNYLYNVL 119
Query: 116 ERPRGWALLYHALVFLIVLGCLILAVLTTFKEYETVSGDWLLLLETFAIFIFGAEFALRI 175
ERPRGWA +YHA VFL+V GCLIL+V +T E+ ++ LL+LE I +FG EF +RI
Sbjct: 120 ERPRGWAFIYHAFVFLLVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVFGLEFIIRI 179
Query: 176 WAAGCCCRYKGWRGRLKFARKPLCMLDIFVLIASVPVVAVGNQGNVLATS-LRSLRFLQI 234
W+AGCCCRY+GW+GRL+FARKP C++D VLIAS+ VV+ QGN+ ATS LRSLRFLQI
Sbjct: 180 WSAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSALRSLRFLQI 239
Query: 235 LRMLRMDRRGGTWKLLGSAICAHSKELITAWYIGFLTLILSSFLVYLVEKDVPEVDAQGE 294
LRM+RMDRRGGTWKLLGS + AHSKELITAWYIGFL LI SSFLVYLVEKD
Sbjct: 240 LRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDA-------- 291
Query: 295 EMKEEFETYADALWWGLITLATIGYGDKTPKTWEGRLIAATFSLIGVSFFALPAGILGSG 354
+EF TYADALWWG ITL TIGYGDKTP TW GRL++A F+L+G+SFFALPAGILGSG
Sbjct: 292 --NKEFSTYADALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSG 349
Query: 355 LALKVQEQHRQKHFEKRRKPAAELIQAAWRYYATNPNRIDLVATWR-FYESVVSFPFFRK 413
ALKVQEQHRQKHFEKRR PAA LIQ WR YA + + +ATW+ +++ + +K
Sbjct: 350 FALKVQEQHRQKHFEKRRNPAANLIQCVWRSYAADEKSVS-IATWKPHLKALHTCSPTKK 408
Query: 414 EQLEAAS-------------------SQKLGLLDRVRLSNPRGSNTK------GKLFTPL 448
EQ EA+S SQKL +RVR+++PRG + K G +P
Sbjct: 409 EQGEASSSKFCSNKQKLFRMYTSRKQSQKLSFKERVRMASPRGQSIKSRQASVGDRRSPS 468
Query: 449 NVDAIEESPSKEPKPVGLNNKERFRTAFRMKAYAFWQSSEDAGTG---DPMAEDRGYGND 505
E SP+K K N++ RFR + R+K+ + + DA T D + +++G D
Sbjct: 469 TDITAEGSPTKVQKSWSFNDRTRFRPSLRLKS-SQPKPVIDADTALGTDDVYDEKGCQCD 527
Query: 506 FPIEDMIPTLKAAIRAVRILQFRLYKKKFKETLRPYDVKDVIEQYSAGHLDMLSRIKYLQ 565
+ED+ P LK IRA+RI++F + K+KFKETLRPYDVKDVIEQYSAGHLDML RIK LQ
Sbjct: 528 VSVEDLTPPLKTVIRAIRIMKFHVAKRKFKETLRPYDVKDVIEQYSAGHLDMLCRIKSLQ 587
Query: 566 TRIDMIFTPGPPSTPKHKKSQKGSAFTFPSQQSPRNEPYVARPSTSEIEDQSMMGKFVKV 625
TR+D I G ++ K + E A T+ +D SM+G+ VKV
Sbjct: 588 TRVDQILGKGQITSDKKSR-----------------EKITAEHETT--DDLSMLGRVVKV 628
Query: 626 ERQVQDMGKKLDFLVDMHMQHMER 649
E+QVQ + KLD L+D++ Q + +
Sbjct: 629 EKQVQSIESKLDCLLDIYQQVLRK 652
>gi|236461942 potassium voltage-gated channel, KQT-like subfamily,
member 5 isoform 3 [Homo sapiens]
Length = 942
Score = 582 bits (1500), Expect = e-166
Identities = 339/675 (50%), Positives = 422/675 (62%), Gaps = 77/675 (11%)
Query: 14 GGGDGGGGG-----GGAANPAGGDAAAAGDEERKVGLAPGDVEQVTLALGAGADKDGTLL 68
GG +GG G G AA AGG +G ++ + G L A A DG LL
Sbjct: 7 GGEEGGAAGLWVKSGAAAAAAGGGRLGSGMKDVESGRGR------VLLNSAAARGDGLLL 60
Query: 69 L--------EGGGRDEGQRRTPQG--IGLLAKTPLSRPVK---RNNAKYRRIQTLIYDAL 115
L GGG RR QG + LL K PLS R N KYRR+Q +Y+ L
Sbjct: 61 LGTRAATLGGGGGGLRESRRGKQGARMSLLGK-PLSYTSSQSCRRNVKYRRVQNYLYNVL 119
Query: 116 ERPRGWALLYHALVFLIVLGCLILAVLTTFKEYETVSGDWLLLLETFAIFIFGAEFALRI 175
ERPRGWA +YHA VFL+V GCLIL+V +T E+ ++ LL+LE I +FG EF +RI
Sbjct: 120 ERPRGWAFIYHAFVFLLVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVFGLEFIIRI 179
Query: 176 WAAGCCCRYKGWRGRLKFARKPLCMLDIFVLIASVPVVAVGNQGNVLATS-LRSLRFLQI 234
W+AGCCCRY+GW+GRL+FARKP C++D VLIAS+ VV+ QGN+ ATS LRSLRFLQI
Sbjct: 180 WSAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSALRSLRFLQI 239
Query: 235 LRMLRMDRRGGTWKLLGSAICAHSKELITAWYIGFLTLILSSFLVYLVEKDVPEVDAQGE 294
LRM+RMDRRGGTWKLLGS + AHSKELITAWYIGFL LI SSFLVYLVEKD
Sbjct: 240 LRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDA-------- 291
Query: 295 EMKEEFETYADALWWGLITLATIGYGDKTPKTWEGRLIAATFSLIGVSFFALPAGILGSG 354
+EF TYADALWWG ITL TIGYGDKTP TW GRL++A F+L+G+SFFALPAGILGSG
Sbjct: 292 --NKEFSTYADALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSG 349
Query: 355 LALKVQEQHRQKHFEKRRKPAAELIQAAWRYYATNPNRIDLVATWR-----FYESVVSFP 409
ALKVQEQHRQKHFEKRR PAA LIQ WR YA + + +ATW+ + +
Sbjct: 350 FALKVQEQHRQKHFEKRRNPAANLIQCVWRSYAADEKSVS-IATWKPHLKALHTCSPTNK 408
Query: 410 FFRKEQ------LEAASSQKLGLLDRVRLSNPRGSNTK------GKLFTPLNVDAIEESP 457
F +Q SQKL +RVR+++PRG + K G +P E SP
Sbjct: 409 FCSNKQKLFRMYTSRKQSQKLSFKERVRMASPRGQSIKSRQASVGDRRSPSTDITAEGSP 468
Query: 458 SKEPKPVGLNNKERFRTAFRMKAYAFWQSSEDAGTG---DPMAEDRGYGNDFPIEDMIPT 514
+K K N++ RFR + R+K+ + + DA T D + +++G D +ED+ P
Sbjct: 469 TKVQKSWSFNDRTRFRPSLRLKS-SQPKPVIDADTALGTDDVYDEKGCQCDVSVEDLTPP 527
Query: 515 LKAAIRAVRILQFRLYKKKFKETLRPYDVKDVIEQYSAGHLDMLSRIKYLQTRIDMIFTP 574
LK IRA+RI++F + K+KFKETLRPYDVKDVIEQYSAGHLDML RIK LQTR+D I
Sbjct: 528 LKTVIRAIRIMKFHVAKRKFKETLRPYDVKDVIEQYSAGHLDMLCRIKSLQTRVDQILGK 587
Query: 575 GPPSTPKHKKSQKGSAFTFPSQQSPRNEPYVARPSTSEIEDQSMMGKFVKVERQVQDMGK 634
G ++ K + E A T+ +D SM+G+ VKVE+QVQ +
Sbjct: 588 GQITSDKKSR-----------------EKITAEHETT--DDLSMLGRVVKVEKQVQSIES 628
Query: 635 KLDFLVDMHMQHMER 649
KLD L+D++ Q + +
Sbjct: 629 KLDCLLDIYQQVLRK 643
>gi|26638655 potassium voltage-gated channel KQT-like protein 4
isoform b [Homo sapiens]
Length = 641
Score = 571 bits (1471), Expect = e-162
Identities = 316/628 (50%), Positives = 413/628 (65%), Gaps = 73/628 (11%)
Query: 41 RKVGLAP--GDVEQVTL-ALGAGADKDGTLLLEGGGRDEGQRRTPQGIGLLAKTPLSRPV 97
R++GL P GD + L AL A + G E GG +R G L PL P
Sbjct: 7 RRLGLGPPPGDAPRAELVALTAVQSEQG----EAGGGGSPRRLGLLGSPLPPGAPLPGPG 62
Query: 98 --------KRNNA---KYRRIQTLIYDALERPRGWALLYHALVFLIVLGCLILAVLTTFK 146
+R++A +YRR+Q +Y+ LERPRGWA +YH +FL+V CL+L+VL+T +
Sbjct: 63 SGSGSACGQRSSAAHKRYRRLQNWVYNVLERPRGWAFVYHVFIFLLVFSCLVLSVLSTIQ 122
Query: 147 EYETVSGDWLLLLETFAIFIFGAEFALRIWAAGCCCRYKGWRGRLKFARKPLCMLDIFVL 206
E++ ++ + LL+LE I +FG E+ +R+W+AGCCCRY+GW+GR +FARKP C++D V
Sbjct: 123 EHQELANECLLILEFVMIVVFGLEYIVRVWSAGCCCRYRGWQGRFRFARKPFCVIDFIVF 182
Query: 207 IASVPVVAVGNQGNVLATS-LRSLRFLQILRMLRMDRRGGTWKLLGSAICAHSKELITAW 265
+ASV V+A G QGN+ ATS LRS+RFLQILRM+RMDRRGGTWKLLGS + AHSKELITAW
Sbjct: 183 VASVAVIAAGTQGNIFATSALRSMRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAW 242
Query: 266 YIGFLTLILSSFLVYLVEKDVPEVDAQGEEMKEEFETYADALWWGLITLATIGYGDKTPK 325
YIGFL LI +SFLVYL EKD +F +YAD+LWWG ITL TIGYGDKTP
Sbjct: 243 YIGFLVLIFASFLVYLAEKDA----------NSDFSSYADSLWWGTITLTTIGYGDKTPH 292
Query: 326 TWEGRLIAATFSLIGVSFFALPAGILGSGLALKVQEQHRQKHFEKRRKPAAELIQAAWRY 385
TW GR++AA F+L+G+SFFALPAGILGSG ALKVQEQHRQKHFEKRR PAA LIQAAWR
Sbjct: 293 TWLGRVLAAGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEKRRMPAANLIQAAWRL 352
Query: 386 YATNPNRIDLVATWRFYESVVSFPFFRKEQLEAASSQKLGLLDRVRL--SNPRGSNTKGK 443
Y+T+ +R L ATW +Y+S++ P F S ++G+ DR+R+ S R +K
Sbjct: 353 YSTDMSRAYLTATWYYYDSIL--PSF---------SSRMGIKDRIRMGSSQRRTGPSKQH 401
Query: 444 LFTPL-----NVDAIEE--SPSKEPKPVGLNNKERFRTAFRMKAYAFWQSSEDAGTGDPM 496
L P + + + E SP+K K N++ RFR + R+K S+EDA + +
Sbjct: 402 LAPPTMPTSPSSEQVGEATSPTKVQKSWSFNDRTRFRASLRLKPRT---SAEDA-PSEEV 457
Query: 497 AEDRGYGNDFPIEDMIPTLKAAIRAVRILQFRLYKKKFKETLRPYDVKDVIEQYSAGHLD 556
AE++ Y + ++D++P +K IR++RIL+F + K+KFKETLRPYDVKDVIEQYSAGHLD
Sbjct: 458 AEEKSYQCELTVDDIMPAVKTVIRSIRILKFLVAKRKFKETLRPYDVKDVIEQYSAGHLD 517
Query: 557 MLSRIKYLQTRIDMIFTPGPPSTPKHKKSQKGSAFTFPSQQSPRNEPYVARPSTSEIEDQ 616
ML RIK LQTR+D I GP +K KG PS +E+ D+
Sbjct: 518 MLGRIKSLQTRVDQIVGRGPGDRKAREKGDKG-------------------PSDAEVVDE 558
Query: 617 -SMMGKFVKVERQVQDMGKKLDFLVDMH 643
SMMG+ VKVE+QVQ + KLD L+ +
Sbjct: 559 ISMMGRVVKVEKQVQSIEHKLDLLLGFY 586
>gi|26638653 potassium voltage-gated channel KQT-like protein 4
isoform a [Homo sapiens]
Length = 695
Score = 559 bits (1441), Expect = e-159
Identities = 319/673 (47%), Positives = 419/673 (62%), Gaps = 109/673 (16%)
Query: 41 RKVGLAP--GDVEQVTL-ALGAGADKDGTLLLEGGGRDEGQRRTPQGIGLLAKTPLSRPV 97
R++GL P GD + L AL A + G E GG +R G L PL P
Sbjct: 7 RRLGLGPPPGDAPRAELVALTAVQSEQG----EAGGGGSPRRLGLLGSPLPPGAPLPGPG 62
Query: 98 --------KRNNA---KYRRIQTLIYDALERPRGWALLYHALVFLIVLGCLILAVLTTFK 146
+R++A +YRR+Q +Y+ LERPRGWA +YH +FL+V CL+L+VL+T +
Sbjct: 63 SGSGSACGQRSSAAHKRYRRLQNWVYNVLERPRGWAFVYHVFIFLLVFSCLVLSVLSTIQ 122
Query: 147 EYETVSGDWLLLLETFAIFIFGAEFALRIWAAGCCCRYKGWRGRLKFARKPLCMLDIFVL 206
E++ ++ + LL+LE I +FG E+ +R+W+AGCCCRY+GW+GR +FARKP C++D V
Sbjct: 123 EHQELANECLLILEFVMIVVFGLEYIVRVWSAGCCCRYRGWQGRFRFARKPFCVIDFIVF 182
Query: 207 IASVPVVAVGNQGNVLATS-LRSLRFLQILRMLRMDRRGGTWKLLGSAICAHSKELITAW 265
+ASV V+A G QGN+ ATS LRS+RFLQILRM+RMDRRGGTWKLLGS + AHSKELITAW
Sbjct: 183 VASVAVIAAGTQGNIFATSALRSMRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAW 242
Query: 266 YIGFLTLILSSFLVYLVEKDVPEVDAQGEEMKEEFETYADALWWGLITLATIGYGDKTPK 325
YIGFL LI +SFLVYL EKD +F +YAD+LWWG ITL TIGYGDKTP
Sbjct: 243 YIGFLVLIFASFLVYLAEKDA----------NSDFSSYADSLWWGTITLTTIGYGDKTPH 292
Query: 326 TWEGRLIAATFSLIGVSFFALPAGILGSGLALKVQEQHRQKHFEKRRKPAAELIQAAWRY 385
TW GR++AA F+L+G+SFFALPAGILGSG ALKVQEQHRQKHFEKRR PAA LIQAAWR
Sbjct: 293 TWLGRVLAAGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEKRRMPAANLIQAAWRL 352
Query: 386 YATNPNRIDLVATWRFYESVVSFPFFRK-----EQLEAA--------------------- 419
Y+T+ +R L ATW +Y+S++ P FR+ E ++ A
Sbjct: 353 YSTDMSRAYLTATWYYYDSIL--PSFRELALLFEHVQRARNGGLRPLEVRRAPVPDGAPS 410
Query: 420 -------------------SSQKLGLLDRVRL--SNPRGSNTKGKLFTPL-----NVDAI 453
S ++G+ DR+R+ S R +K L P + + +
Sbjct: 411 RYPPVATCHRPGSTSFCPGESSRMGIKDRIRMGSSQRRTGPSKQHLAPPTMPTSPSSEQV 470
Query: 454 EE--SPSKEPKPVGLNNKERFRTAFRMKAYAFWQSSEDAGTGDPMAEDRGYGNDFPIEDM 511
E SP+K K N++ RFR + R+K S+EDA + +AE++ Y + ++D+
Sbjct: 471 GEATSPTKVQKSWSFNDRTRFRASLRLKPRT---SAEDA-PSEEVAEEKSYQCELTVDDI 526
Query: 512 IPTLKAAIRAVRILQFRLYKKKFKETLRPYDVKDVIEQYSAGHLDMLSRIKYLQTRIDMI 571
+P +K IR++RIL+F + K+KFKETLRPYDVKDVIEQYSAGHLDML RIK LQTR+D I
Sbjct: 527 MPAVKTVIRSIRILKFLVAKRKFKETLRPYDVKDVIEQYSAGHLDMLGRIKSLQTRVDQI 586
Query: 572 FTPGPPSTPKHKKSQKGSAFTFPSQQSPRNEPYVARPSTSEIEDQ-SMMGKFVKVERQVQ 630
GP +K KG PS +E+ D+ SMMG+ VKVE+QVQ
Sbjct: 587 VGRGPGDRKAREKGDKG-------------------PSDAEVVDEISMMGRVVKVEKQVQ 627
Query: 631 DMGKKLDFLVDMH 643
+ KLD L+ +
Sbjct: 628 SIEHKLDLLLGFY 640
>gi|26051268 potassium voltage-gated channel KQT-like protein 2
isoform e [Homo sapiens]
Length = 393
Score = 462 bits (1190), Expect = e-130
Identities = 241/398 (60%), Positives = 289/398 (72%), Gaps = 32/398 (8%)
Query: 39 EERKVGLAPGDVEQVTLALG-AGAD-------KDGTLLLEGGGRDEGQRRTPQGIGLLAK 90
+ R G+ PG + L +G G D +DG LL+ G P+ +L+K
Sbjct: 4 KSRNGGVYPGPSGEKKLKVGFVGLDPGAPDSTRDGALLIAGS-------EAPKRGSILSK 56
Query: 91 -----TPLSRPVKRNNAKYRRIQTLIYDALERPRGWALLYHALVFLIVLGCLILAVLTTF 145
+P KRN A YR++Q +Y+ LERPRGWA +YHA VFL+V CL+L+V +T
Sbjct: 57 PRAGGAGAGKPPKRN-AFYRKLQNFLYNVLERPRGWAFIYHAYVFLLVFSCLVLSVFSTI 115
Query: 146 KEYETVSGDWLLLLETFAIFIFGAEFALRIWAAGCCCRYKGWRGRLKFARKPLCMLDIFV 205
KEYE S L +LE I +FG E+ +RIWAAGCCCRY+GWRGRLKFARKP C++DI V
Sbjct: 116 KEYEKSSEGALYILEIVTIVVFGVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMV 175
Query: 206 LIASVPVVAVGNQGNVLATS-LRSLRFLQILRMLRMDRRGGTWKLLGSAICAHSKELITA 264
LIAS+ V+A G+QGNV ATS LRSLRFLQILRM+RMDRRGGTWKLLGS + AHSKEL+TA
Sbjct: 176 LIASIAVLAAGSQGNVFATSALRSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELVTA 235
Query: 265 WYIGFLTLILSSFLVYLVEKDVPEVDAQGEEMKEEFETYADALWWGLITLATIGYGDKTP 324
WYIGFL LIL+SFLVYL EK GE + F+TYADALWWGLITL TIGYGDK P
Sbjct: 236 WYIGFLCLILASFLVYLAEK--------GEN--DHFDTYADALWWGLITLTTIGYGDKYP 285
Query: 325 KTWEGRLIAATFSLIGVSFFALPAGILGSGLALKVQEQHRQKHFEKRRKPAAELIQAAWR 384
+TW GRL+AATF+LIGVSFFALPAGILGSG ALKVQEQHRQKHFEKRR PAA LIQ+AWR
Sbjct: 286 QTWNGRLLAATFTLIGVSFFALPAGILGSGFALKVQEQHRQKHFEKRRNPAAGLIQSAWR 345
Query: 385 YYATNPNRIDLVATWRFYESVVSFPFFRKEQLEAASSQ 422
+YATN +R DL +TW++YE V+ P +R + A+ Q
Sbjct: 346 FYATNLSRTDLHSTWQYYERTVTVPMYRYRRRAPATKQ 383
>gi|236462242 potassium voltage-gated channel, KQT-like subfamily,
member 5 isoform 5 [Homo sapiens]
Length = 822
Score = 442 bits (1138), Expect = e-124
Identities = 244/427 (57%), Positives = 290/427 (67%), Gaps = 38/427 (8%)
Query: 14 GGGDGGGGG-----GGAANPAGGDAAAAGDEERKVGLAPGDVEQVTLALGAGADKDGTLL 68
GG +GG G G AA AGG +G ++ + G L A A DG LL
Sbjct: 7 GGEEGGAAGLWVKSGAAAAAAGGGRLGSGMKDVESGRGR------VLLNSAAARGDGLLL 60
Query: 69 L--------EGGGRDEGQRRTPQG--IGLLAKTPLSRPVK---RNNAKYRRIQTLIYDAL 115
L GGG RR QG + LL K PLS R N KYRR+Q +Y+ L
Sbjct: 61 LGTRAATLGGGGGGLRESRRGKQGARMSLLGK-PLSYTSSQSCRRNVKYRRVQNYLYNVL 119
Query: 116 ERPRGWALLYHALVFLIVLGCLILAVLTTFKEYETVSGDWLLLLETFAIFIFGAEFALRI 175
ERPRGWA +YHA VFL+V GCLIL+V +T E+ ++ LL+LE I +FG EF +RI
Sbjct: 120 ERPRGWAFIYHAFVFLLVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVFGLEFIIRI 179
Query: 176 WAAGCCCRYKGWRGRLKFARKPLCMLDIFVLIASVPVVAVGNQGNVLATS-LRSLRFLQI 234
W+AGCCCRY+GW+GRL+FARKP C++D VLIAS+ VV+ QGN+ ATS LRSLRFLQI
Sbjct: 180 WSAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSALRSLRFLQI 239
Query: 235 LRMLRMDRRGGTWKLLGSAICAHSKELITAWYIGFLTLILSSFLVYLVEKDVPEVDAQGE 294
LRM+RMDRRGGTWKLLGS + AHSKELITAWYIGFL LI SSFLVYLVEKD
Sbjct: 240 LRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDA-------- 291
Query: 295 EMKEEFETYADALWWGLITLATIGYGDKTPKTWEGRLIAATFSLIGVSFFALPAGILGSG 354
+EF TYADALWWG ITL TIGYGDKTP TW GRL++A F+L+G+SFFALPAGILGSG
Sbjct: 292 --NKEFSTYADALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSG 349
Query: 355 LALKVQEQHRQKHFEKRRKPAAELIQAAWRYYATNPNRIDLVATWR-FYESVVSFPFFRK 413
ALKVQEQHRQKHFEKRR PAA LIQ WR YA + + +ATW+ +++ + +K
Sbjct: 350 FALKVQEQHRQKHFEKRRNPAANLIQCVWRSYAADEKSVS-IATWKPHLKALHTCSPTKK 408
Query: 414 EQLEAAS 420
EQ EA+S
Sbjct: 409 EQGEASS 415
Score = 108 bits (269), Expect = 3e-23
Identities = 61/127 (48%), Positives = 80/127 (62%), Gaps = 19/127 (14%)
Query: 523 RILQFRLYKKKFKETLRPYDVKDVIEQYSAGHLDMLSRIKYLQTRIDMIFTPGPPSTPKH 582
RI++F + K+KFKETLRPYDVKDVIEQYSAGHLDML RIK LQTR+D I G ++ K
Sbjct: 416 RIMKFHVAKRKFKETLRPYDVKDVIEQYSAGHLDMLCRIKSLQTRVDQILGKGQITSDKK 475
Query: 583 KKSQKGSAFTFPSQQSPRNEPYVARPSTSEIEDQSMMGKFVKVERQVQDMGKKLDFLVDM 642
+ E A T+ +D SM+G+ VKVE+QVQ + KLD L+D+
Sbjct: 476 SR-----------------EKITAEHETT--DDLSMLGRVVKVEKQVQSIESKLDCLLDI 516
Query: 643 HMQHMER 649
+ Q + +
Sbjct: 517 YQQVLRK 523
>gi|32479527 potassium voltage-gated channel, KQT-like subfamily,
member 1 isoform 1 [Homo sapiens]
Length = 676
Score = 363 bits (931), Expect = e-100
Identities = 211/504 (41%), Positives = 294/504 (58%), Gaps = 45/504 (8%)
Query: 107 IQTLIYDALERPRGW-ALLYHALVFLIVLGCLILAVLTTFKEYETVSGDWLLLLETFAIF 165
+Q +Y+ LERP GW +YH VFLIVL CLI +VL+T ++Y ++ L +E +
Sbjct: 106 VQGRVYNFLERPTGWKCFVYHFAVFLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLVV 165
Query: 166 IFGAEFALRIWAAGCCCRYKGWRGRLKFARKPLCMLDIFVLIASVPVVAVGNQGNVLATS 225
FG E+ +R+W+AGC +Y G GRL+FARKP+ ++D+ V++AS+ V+ VG++G V ATS
Sbjct: 166 FFGTEYVVRLWSAGCRSKYVGLWGRLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATS 225
Query: 226 -LRSLRFLQILRMLRMDRRGGTWKLLGSAICAHSKELITAWYIGFLTLILSSFLVYLVEK 284
+R +RFLQILRML +DR+GGTW+LLGS + H +ELIT YIGFL LI SS+ VYL EK
Sbjct: 226 AIRGIRFLQILRMLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEK 285
Query: 285 DVPEVDAQGEEMKEEFETYADALWWGLITLATIGYGDKTPKTWEGRLIAATFSLIGVSFF 344
D A E + EF +YADALWWG++T+ TIGYGDK P+TW G+ IA+ FS+ +SFF
Sbjct: 286 D-----AVNESGRVEFGSYADALWWGVVTVTTIGYGDKVPQTWVGKTIASCFSVFAISFF 340
Query: 345 ALPAGILGSGLALKVQEQHRQKHFEKRRKPAAELIQAAWRYYAT-NPNRIDLVATWRFYE 403
ALPAGILGSG ALKVQ++ RQKHF ++ AA LIQ AWR YA NP+ +TW+ Y
Sbjct: 341 ALPAGILGSGFALKVQQKQRQKHFNRQIPAAASLIQTAWRCYAAENPDS----STWKIYI 396
Query: 404 SVVSFPFFRKEQLEAASSQKLGLLDRVRLSNPRGSNTKGKLFT---------------PL 448
+ + +L G K+ T
Sbjct: 397 RKAPRSHTLLSPSPKPKKSVVVKKKKFKLDKDNGVTPGEKMLTVPHITCDPPEERRLDHF 456
Query: 449 NVDAIEESPSKEPKPVGLNNKERFRTAFRMKAYAFWQSSEDAGTGDPMAEDRGYGNDFPI 508
+VD + S K P + ++ RT ++A E P+ I
Sbjct: 457 SVDGYDSSVRKSPTLLEVSMPHFMRT----NSFAEDLDLEGETLLTPITH---------I 503
Query: 509 EDMIPTLKAAIRAVRILQFRLYKKKFKETLRPYDVKDVIEQYSAGHLDMLSRIKYLQTRI 568
+ +A I+ +R +Q+ + KKKF++ +PYDV+DVIEQYS GHL+++ RIK LQ R+
Sbjct: 504 SQLREHHRATIKVIRRMQYFVAKKKFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRL 563
Query: 569 DMIFTPGPPS---TPKHKKSQKGS 589
D + G PS + K +GS
Sbjct: 564 DQ--SIGKPSLFISVSEKSKDRGS 585
>gi|32479525 potassium voltage-gated channel, KQT-like subfamily,
member 1 isoform 2 [Homo sapiens]
Length = 549
Score = 342 bits (876), Expect = 1e-93
Identities = 200/480 (41%), Positives = 279/480 (58%), Gaps = 44/480 (9%)
Query: 130 FLIVLGCLILAVLTTFKEYETVSGDWLLLLETFAIFIFGAEFALRIWAAGCCCRYKGWRG 189
FLIVL CLI +VL+T ++Y ++ L +E + FG E+ +R+W+AGC +Y G G
Sbjct: 3 FLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGLWG 62
Query: 190 RLKFARKPLCMLDIFVLIASVPVVAVGNQGNVLATS-LRSLRFLQILRMLRMDRRGGTWK 248
RL+FARKP+ ++D+ V++AS+ V+ VG++G V ATS +R +RFLQILRML +DR+GGTW+
Sbjct: 63 RLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWR 122
Query: 249 LLGSAICAHSKELITAWYIGFLTLILSSFLVYLVEKDVPEVDAQGEEMKEEFETYADALW 308
LLGS + H +ELIT YIGFL LI SS+ VYL EKD A E + EF +YADALW
Sbjct: 123 LLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKD-----AVNESGRVEFGSYADALW 177
Query: 309 WGLITLATIGYGDKTPKTWEGRLIAATFSLIGVSFFALPAGILGSGLALKVQEQHRQKHF 368
WG++T+ TIGYGDK P+TW G+ IA+ FS+ +SFFALPAGILGSG ALKVQ++ RQKHF
Sbjct: 178 WGVVTVTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHF 237
Query: 369 EKRRKPAAELIQAAWRYYAT-NPNRIDLVATWRFYESVVSFPFFRKEQLEAASSQKLGLL 427
++ AA LIQ AWR YA NP+ +TW+ Y +
Sbjct: 238 NRQIPAAASLIQTAWRCYAAENPDS----STWKIYIRKAPRSHTLLSPSPKPKKSVVVKK 293
Query: 428 DRVRLSNPRGSNTKGKLFT---------------PLNVDAIEESPSKEPKPVGLNNKERF 472
+ +L G K+ T +VD + S K P + ++
Sbjct: 294 KKFKLDKDNGVTPGEKMLTVPHITCDPPEERRLDHFSVDGYDSSVRKSPTLLEVSMPHFM 353
Query: 473 RTAFRMKAYAFWQSSEDAGTGDPMAEDRGYGNDFPIEDMIPTLKAAIRAVRILQFRLYKK 532
RT ++A E P+ I + +A I+ +R +Q+ + KK
Sbjct: 354 RT----NSFAEDLDLEGETLLTPITH---------ISQLREHHRATIKVIRRMQYFVAKK 400
Query: 533 KFKETLRPYDVKDVIEQYSAGHLDMLSRIKYLQTRIDMIFTPGPPS---TPKHKKSQKGS 589
KF++ +PYDV+DVIEQYS GHL+++ RIK LQ R+D + G PS + K +GS
Sbjct: 401 KFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLDQ--SIGKPSLFISVSEKSKDRGS 458
>gi|119395748 potassium voltage-gated channel subfamily A member 1
[Homo sapiens]
Length = 495
Score = 85.5 bits (210), Expect = 2e-16
Identities = 57/214 (26%), Positives = 102/214 (47%), Gaps = 15/214 (7%)
Query: 143 TTFKEYETVSGDWLLLLETFAIFIFGAEFALRIWAAGCCCRYKGWRGRLKFARKPLCMLD 202
TT + D ++ET I F E +R +A C + ++ + F + ++
Sbjct: 208 TTVIYNSNIFTDPFFIVETLCIIWFSFELVVRFFA--CPSKTDFFKNIMNFI-DIVAIIP 264
Query: 203 IFVLIASVPVVAVGNQGNVLATSL---RSLRFLQILRMLRMDRRGGTWKLLGSAICAHSK 259
F+ + + GNQ ATSL R +R +++ R+ ++ R ++LG + A +
Sbjct: 265 YFITLGTEIAEQEGNQKGEQATSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMR 324
Query: 260 ELITAWYIGFLTLILSSFLVYLVEKDVPEVDAQGEEMKEEFETYADALWWGLITLATIGY 319
EL + F+ +IL S VY A+ EE + F + DA WW ++++ T+GY
Sbjct: 325 ELGLLIFFLFIGVILFSSAVYF---------AEAEEAESHFSSIPDAFWWAVVSMTTVGY 375
Query: 320 GDKTPKTWEGRLIAATFSLIGVSFFALPAGILGS 353
GD P T G+++ + ++ GV ALP ++ S
Sbjct: 376 GDMYPVTIGGKIVGSLCAIAGVLTIALPVPVIVS 409
>gi|4826782 potassium voltage-gated channel, shaker-related
subfamily, member 2 [Homo sapiens]
Length = 499
Score = 82.8 bits (203), Expect = 1e-15
Identities = 54/204 (26%), Positives = 96/204 (47%), Gaps = 16/204 (7%)
Query: 154 DWLLLLETFAIFIFGAEFALRIWAAGCCCRYKGWRGRLKFARKPLCMLDIFVLI----AS 209
D ++ET I F EF +R +A C G+ + + ++ F+ + A
Sbjct: 220 DPFFIVETLCIIWFSFEFLVRFFA---CPSKAGFFTNIMNIIDIVAIIPYFITLGTELAE 276
Query: 210 VPVVAVGNQGNVLATSLRSLRFLQILRMLRMDRRGGTWKLLGSAICAHSKELITAWYIGF 269
P A Q + LR +R +++ R+ ++ R ++LG + A +EL + F
Sbjct: 277 KPEDAQQGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLF 336
Query: 270 LTLILSSFLVYLVEKDVPEVDAQGEEMKEEFETYADALWWGLITLATIGYGDKTPKTWEG 329
+ +IL S VY E D E + +F + DA WW ++++ T+GYGD P T G
Sbjct: 337 IGVILFSSAVYFAEAD---------ERESQFPSIPDAFWWAVVSMTTVGYGDMVPTTIGG 387
Query: 330 RLIAATFSLIGVSFFALPAGILGS 353
+++ + ++ GV ALP ++ S
Sbjct: 388 KIVGSLCAIAGVLTIALPVPVIVS 411
>gi|88758576 Shaw-related voltage-gated potassium channel protein 4
isoform c [Homo sapiens]
Length = 626
Score = 82.0 bits (201), Expect = 2e-15
Identities = 57/223 (25%), Positives = 101/223 (45%), Gaps = 15/223 (6%)
Query: 156 LLLLETFAIFIFGAEFALRIWAAGCCCRYKGWRGRLKFARKPLCMLDIFVLIASVPVVAV 215
L +E + F EF +RI CC L F + L ++D ++ V +
Sbjct: 281 LTYIEGVCVLWFTLEFLVRI----VCCP-----DTLDFVKNLLNIIDFVAILPFYLEVGL 331
Query: 216 GNQGNVLATS----LRSLRFLQILRMLRMDRRGGTWKLLGSAICAHSKE-LITAWYIGFL 270
+ A LR +RF++ILR+ ++ R ++LG + A + E L+ ++
Sbjct: 332 SGLSSKAARDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALG 391
Query: 271 TLILSSFLVYLVEKDVPEVDAQGEEMKEEFETYADALWWGLITLATIGYGDKTPKTWEGR 330
LI ++ + Y D +G + +F+ WW ++T+ T+GYGD PKTW G
Sbjct: 392 VLIFATMIYYAERIGARPSDPRGND-HTDFKNIPIGFWWAVVTMTTLGYGDMYPKTWSGM 450
Query: 331 LIAATFSLIGVSFFALPAGILGSGLALKVQEQHRQKHFEKRRK 373
L+ A +L GV A+P ++ + + ++ K+RK
Sbjct: 451 LVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKRK 493
>gi|24497462 Shaw-related voltage-gated potassium channel protein 4
isoform a [Homo sapiens]
Length = 635
Score = 82.0 bits (201), Expect = 2e-15
Identities = 57/223 (25%), Positives = 101/223 (45%), Gaps = 15/223 (6%)
Query: 156 LLLLETFAIFIFGAEFALRIWAAGCCCRYKGWRGRLKFARKPLCMLDIFVLIASVPVVAV 215
L +E + F EF +RI CC L F + L ++D ++ V +
Sbjct: 281 LTYIEGVCVLWFTLEFLVRI----VCCP-----DTLDFVKNLLNIIDFVAILPFYLEVGL 331
Query: 216 GNQGNVLATS----LRSLRFLQILRMLRMDRRGGTWKLLGSAICAHSKE-LITAWYIGFL 270
+ A LR +RF++ILR+ ++ R ++LG + A + E L+ ++
Sbjct: 332 SGLSSKAARDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALG 391
Query: 271 TLILSSFLVYLVEKDVPEVDAQGEEMKEEFETYADALWWGLITLATIGYGDKTPKTWEGR 330
LI ++ + Y D +G + +F+ WW ++T+ T+GYGD PKTW G
Sbjct: 392 VLIFATMIYYAERIGARPSDPRGND-HTDFKNIPIGFWWAVVTMTTLGYGDMYPKTWSGM 450
Query: 331 LIAATFSLIGVSFFALPAGILGSGLALKVQEQHRQKHFEKRRK 373
L+ A +L GV A+P ++ + + ++ K+RK
Sbjct: 451 LVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKRK 493
>gi|24497464 Shaw-related voltage-gated potassium channel protein 4
isoform b [Homo sapiens]
Length = 582
Score = 82.0 bits (201), Expect = 2e-15
Identities = 57/223 (25%), Positives = 101/223 (45%), Gaps = 15/223 (6%)
Query: 156 LLLLETFAIFIFGAEFALRIWAAGCCCRYKGWRGRLKFARKPLCMLDIFVLIASVPVVAV 215
L +E + F EF +RI CC L F + L ++D ++ V +
Sbjct: 281 LTYIEGVCVLWFTLEFLVRI----VCCP-----DTLDFVKNLLNIIDFVAILPFYLEVGL 331
Query: 216 GNQGNVLATS----LRSLRFLQILRMLRMDRRGGTWKLLGSAICAHSKE-LITAWYIGFL 270
+ A LR +RF++ILR+ ++ R ++LG + A + E L+ ++
Sbjct: 332 SGLSSKAARDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALG 391
Query: 271 TLILSSFLVYLVEKDVPEVDAQGEEMKEEFETYADALWWGLITLATIGYGDKTPKTWEGR 330
LI ++ + Y D +G + +F+ WW ++T+ T+GYGD PKTW G
Sbjct: 392 VLIFATMIYYAERIGARPSDPRGND-HTDFKNIPIGFWWAVVTMTTLGYGDMYPKTWSGM 450
Query: 331 LIAATFSLIGVSFFALPAGILGSGLALKVQEQHRQKHFEKRRK 373
L+ A +L GV A+P ++ + + ++ K+RK
Sbjct: 451 LVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKRK 493
>gi|88758565 potassium voltage-gated channel, shaker-related
subfamily, member 3 [Homo sapiens]
Length = 575
Score = 80.5 bits (197), Expect = 6e-15
Identities = 55/207 (26%), Positives = 95/207 (45%), Gaps = 25/207 (12%)
Query: 154 DWLLLLETFAIFIFGAEFALRIWAAGCCCRYKGWRGRLKFARKPLCMLDIFVLIA---SV 210
D ++ET I F E +R +A + F+R + ++DI +I ++
Sbjct: 293 DPFFVVETLCIIWFSFELLVRFFACP---------SKATFSRNIMNLIDIVAIIPYFITL 343
Query: 211 PVVAVGNQGN----VLATSLRSLRFLQILRMLRMDRRGGTWKLLGSAICAHSKELITAWY 266
QGN + LR +R +++ R+ ++ R ++LG + A +EL +
Sbjct: 344 GTELAERQGNGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIF 403
Query: 267 IGFLTLILSSFLVYLVEKDVPEVDAQGEEMKEEFETYADALWWGLITLATIGYGDKTPKT 326
F+ +IL S VY E D P F + DA WW ++T+ T+GYGD P T
Sbjct: 404 FLFIGVILFSSAVYFAEADDPT---------SGFSSIPDAFWWAVVTMTTVGYGDMHPVT 454
Query: 327 WEGRLIAATFSLIGVSFFALPAGILGS 353
G+++ + ++ GV ALP ++ S
Sbjct: 455 IGGKIVGSLCAIAGVLTIALPVPVIVS 481
>gi|21217561 Shaw-related voltage-gated potassium channel protein 2
isoform KV3.2a [Homo sapiens]
Length = 613
Score = 80.5 bits (197), Expect = 6e-15
Identities = 74/341 (21%), Positives = 145/341 (42%), Gaps = 37/341 (10%)
Query: 69 LEGGGRDEGQRRTPQGIGLLAKTPLSRPVKRNNAKYRRIQTLIYDALERP---RGWALLY 125
L GG + + + +G+ L P ++ ++RR+Q ++ E P R +
Sbjct: 174 LIGGDPGDDEDLAAKRLGIEDAAGLGGPDGKSG-RWRRLQPRMWALFEDPYSSRAARFIA 232
Query: 126 HALVFLIVLG----CL---------------ILAVLTTFKEYETVSGDWLLLLETFAIFI 166
A +F I++ CL ++ + +YE + L +E +
Sbjct: 233 FASLFFILVSITTFCLETHEAFNIVKNKTEPVINGTSVVLQYEIETDPALTYVEGVCVVW 292
Query: 167 FGAEFALRIWAAGCCCRYKGWRGRLKFARKPLCMLDIFVLIASVPVVAVGNQGNVLATS- 225
F EF +RI + +L+F + L ++D ++ V + + A
Sbjct: 293 FTFEFLVRIVFSP---------NKLEFIKNLLNIIDFVAILPFYLEVGLSGLSSKAAKDV 343
Query: 226 ---LRSLRFLQILRMLRMDRRGGTWKLLGSAICAHSKELITAWYIGFLTLILSSFLVYLV 282
LR +RF++ILR+ ++ R ++LG + A + E + L +++ + ++Y
Sbjct: 344 LGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYA 403
Query: 283 EKDVPEVDAQGEEMKEEFETYADALWWGLITLATIGYGDKTPKTWEGRLIAATFSLIGVS 342
E+ + + +F+ WW ++T+ T+GYGD P+TW G L+ A +L GV
Sbjct: 404 ERVGAQPNDPSASEHTQFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVL 463
Query: 343 FFALPAGILGSGLALKVQ-EQHRQKHFEKRRKPAAELIQAA 382
A+P ++ + + +QK KR+K QA+
Sbjct: 464 TIAMPVPVIVNNFGMYYSLAMAKQKLPRKRKKHIPPAPQAS 504
>gi|21217563 Shaw-related voltage-gated potassium channel protein 2
isoform KV3.2b [Homo sapiens]
Length = 638
Score = 80.5 bits (197), Expect = 6e-15
Identities = 74/341 (21%), Positives = 145/341 (42%), Gaps = 37/341 (10%)
Query: 69 LEGGGRDEGQRRTPQGIGLLAKTPLSRPVKRNNAKYRRIQTLIYDALERP---RGWALLY 125
L GG + + + +G+ L P ++ ++RR+Q ++ E P R +
Sbjct: 174 LIGGDPGDDEDLAAKRLGIEDAAGLGGPDGKSG-RWRRLQPRMWALFEDPYSSRAARFIA 232
Query: 126 HALVFLIVLG----CL---------------ILAVLTTFKEYETVSGDWLLLLETFAIFI 166
A +F I++ CL ++ + +YE + L +E +
Sbjct: 233 FASLFFILVSITTFCLETHEAFNIVKNKTEPVINGTSVVLQYEIETDPALTYVEGVCVVW 292
Query: 167 FGAEFALRIWAAGCCCRYKGWRGRLKFARKPLCMLDIFVLIASVPVVAVGNQGNVLATS- 225
F EF +RI + +L+F + L ++D ++ V + + A
Sbjct: 293 FTFEFLVRIVFSP---------NKLEFIKNLLNIIDFVAILPFYLEVGLSGLSSKAAKDV 343
Query: 226 ---LRSLRFLQILRMLRMDRRGGTWKLLGSAICAHSKELITAWYIGFLTLILSSFLVYLV 282
LR +RF++ILR+ ++ R ++LG + A + E + L +++ + ++Y
Sbjct: 344 LGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYA 403
Query: 283 EKDVPEVDAQGEEMKEEFETYADALWWGLITLATIGYGDKTPKTWEGRLIAATFSLIGVS 342
E+ + + +F+ WW ++T+ T+GYGD P+TW G L+ A +L GV
Sbjct: 404 ERVGAQPNDPSASEHTQFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVL 463
Query: 343 FFALPAGILGSGLALKVQ-EQHRQKHFEKRRKPAAELIQAA 382
A+P ++ + + +QK KR+K QA+
Sbjct: 464 TIAMPVPVIVNNFGMYYSLAMAKQKLPRKRKKHIPPAPQAS 504
>gi|24497458 Shaw-related voltage-gated potassium channel protein 2
isoform KV3.2c [Homo sapiens]
Length = 558
Score = 80.5 bits (197), Expect = 6e-15
Identities = 74/341 (21%), Positives = 145/341 (42%), Gaps = 37/341 (10%)
Query: 69 LEGGGRDEGQRRTPQGIGLLAKTPLSRPVKRNNAKYRRIQTLIYDALERP---RGWALLY 125
L GG + + + +G+ L P ++ ++RR+Q ++ E P R +
Sbjct: 174 LIGGDPGDDEDLAAKRLGIEDAAGLGGPDGKSG-RWRRLQPRMWALFEDPYSSRAARFIA 232
Query: 126 HALVFLIVLG----CL---------------ILAVLTTFKEYETVSGDWLLLLETFAIFI 166
A +F I++ CL ++ + +YE + L +E +
Sbjct: 233 FASLFFILVSITTFCLETHEAFNIVKNKTEPVINGTSVVLQYEIETDPALTYVEGVCVVW 292
Query: 167 FGAEFALRIWAAGCCCRYKGWRGRLKFARKPLCMLDIFVLIASVPVVAVGNQGNVLATS- 225
F EF +RI + +L+F + L ++D ++ V + + A
Sbjct: 293 FTFEFLVRIVFSP---------NKLEFIKNLLNIIDFVAILPFYLEVGLSGLSSKAAKDV 343
Query: 226 ---LRSLRFLQILRMLRMDRRGGTWKLLGSAICAHSKELITAWYIGFLTLILSSFLVYLV 282
LR +RF++ILR+ ++ R ++LG + A + E + L +++ + ++Y
Sbjct: 344 LGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYA 403
Query: 283 EKDVPEVDAQGEEMKEEFETYADALWWGLITLATIGYGDKTPKTWEGRLIAATFSLIGVS 342
E+ + + +F+ WW ++T+ T+GYGD P+TW G L+ A +L GV
Sbjct: 404 ERVGAQPNDPSASEHTQFKNIPIGFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVL 463
Query: 343 FFALPAGILGSGLALKVQ-EQHRQKHFEKRRKPAAELIQAA 382
A+P ++ + + +QK KR+K QA+
Sbjct: 464 TIAMPVPVIVNNFGMYYSLAMAKQKLPRKRKKHIPPAPQAS 504
>gi|24497460 Shaw-related voltage-gated potassium channel protein 3
[Homo sapiens]
Length = 757
Score = 79.7 bits (195), Expect = 1e-14
Identities = 93/383 (24%), Positives = 151/383 (39%), Gaps = 41/383 (10%)
Query: 5 ARRAAGAAGGGGDGGGGGGGAANPAGGDAAAAGDEERKVGLAPGDVEQVTLALGAGADKD 64
A AAGA GG D G GG GG A G+ +R G GAG
Sbjct: 213 AANAAGAHDGGLDDEAGAGG-----GGLDGAGGELKRLCFQDAGG--------GAGGPPG 259
Query: 65 GTLLLEGGGRDEGQRRTPQGIGLLAKTPLSRPVKRNNAKYRRIQTLIYDA---LERPRGW 121
G GG RR + L + P S R A LI LE G+
Sbjct: 260 GA----GGAGGTWWRRWQPRVWALFEDPYSSRAARYVAFASLFFILISITTFCLETHEGF 315
Query: 122 ALLYHALVFLIVLGCLILAVLTTFKEYETVSGDWLLLLETFAIFIFGAEFALRIWAAGCC 181
+ + V + A E + +L +E + F EF +RI
Sbjct: 316 IHISNKTV--TQASPIPGAPPENITNVEVETEPFLTYVEGVCVVWFTFEFLMRITFCP-- 371
Query: 182 CRYKGWRGRLKFARKPLCMLDIFVLIASVPVVAVGNQGNVLATS----LRSLRFLQILRM 237
+++F + L ++D ++ V + + A LR +RF++ILR+
Sbjct: 372 -------DKVEFLKSSLNIIDCVAILPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRI 424
Query: 238 LRMDRRGGTWKLLGSAICAHSKELITAWYIGFLTLILSSFLVYLVEKDVPEVDAQGEEMK 297
++ R ++LG + A + E + L +++ + ++Y E+ + D
Sbjct: 425 FKLTRHFVGLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERIGADPDDILGSNH 484
Query: 298 EEFETYADALWWGLITLATIGYGDKTPKTWEGRLIAATFSLIGVSFFALPAGILGS---- 353
F+ WW ++T+ T+GYGD PKTW G L+ A +L GV A+P ++ +
Sbjct: 485 TYFKNIPIGFWWAVVTMTTLGYGDMYPKTWSGMLVGALCALAGVLTIAMPVPVIVNNFGM 544
Query: 354 --GLALKVQEQHRQKHFEKRRKP 374
LA+ Q+ ++K+ R P
Sbjct: 545 YYSLAMAKQKLPKKKNKHIPRPP 567
>gi|4504817 potassium voltage-gated channel, shaker-related
subfamily, member 4 [Homo sapiens]
Length = 653
Score = 79.0 bits (193), Expect = 2e-14
Identities = 54/215 (25%), Positives = 98/215 (45%), Gaps = 29/215 (13%)
Query: 150 TVSGDWLLLLETFAIFIFGAEFALRIWAAGCCCRYKGWRGRLKFARKPLCMLDIFVLIAS 209
T+ D ++ET I F EF +R +A + F + + ++DI ++
Sbjct: 365 TIFNDPFFIVETVCIVWFSFEFVVRCFACP---------SQALFFKNIMNIIDIVSILPY 415
Query: 210 VPVVAV----------GNQGNVLATS-LRSLRFLQILRMLRMDRRGGTWKLLGSAICAHS 258
+ G Q ++ + LR +R +++ R+ ++ R ++LG + A
Sbjct: 416 FITLGTDLAQQQGGGNGQQQQAMSFAILRIIRLVRVFRIFKLSRHSKGLQILGHTLRASM 475
Query: 259 KELITAWYIGFLTLILSSFLVYLVEKDVPEVDAQGEEMKEEFETYADALWWGLITLATIG 318
+EL + F+ +IL S VY E D P F++ DA WW ++T+ T+G
Sbjct: 476 RELGLLIFFLFIGVILFSSAVYFAEADEPTT---------HFQSIPDAFWWAVVTMTTVG 526
Query: 319 YGDKTPKTWEGRLIAATFSLIGVSFFALPAGILGS 353
YGD P T G+++ + ++ GV ALP ++ S
Sbjct: 527 YGDMKPITVGGKIVGSLCAIAGVLTIALPVPVIVS 561
>gi|4826784 potassium voltage-gated channel, Shab-related subfamily,
member 1 [Homo sapiens]
Length = 858
Score = 78.6 bits (192), Expect = 2e-14
Identities = 72/278 (25%), Positives = 126/278 (45%), Gaps = 33/278 (11%)
Query: 111 IYDALERPRGWA---LLYHALVFLIVLGCLILAV-----LTTFKEY-ETVSGDWLLLLET 161
++D LE+P +L + IVL + L++ L + E+ ++ L +E
Sbjct: 175 LWDLLEKPNSSVAAKILAIISIMFIVLSTIALSLNTLPELQSLDEFGQSTDNPQLAHVEA 234
Query: 162 FAIFIFGAEFALRIWAAGCCCRYKGWRGRLKFARKPLCMLDIFVLIAS-VPVVAVGNQGN 220
I F E+ LR ++ K W KF + PL +D+ ++ V + + +
Sbjct: 235 VCIAWFTMEYLLRFLSSP-----KKW----KFFKGPLNAIDLLAILPYYVTIFLTESNKS 285
Query: 221 VLATS-----LRSLRFLQILRMLRMDRRGGTWKLLGSAICAHSKELITAWYIGFLTLILS 275
VL ++ R ++ILR+L++ R + LG + EL + +++
Sbjct: 286 VLQFQNVRRVVQIFRIMRILRILKLARHSTGLQSLGFTLRRSYNELGLLILFLAMGIMIF 345
Query: 276 SFLVYLVEKDVPEVDAQGEEMKEEFETYADALWWGLITLATIGYGDKTPKTWEGRLIAAT 335
S LV+ EKD E +F++ + WW IT+ T+GYGD PKT G+++
Sbjct: 346 SSLVFFAEKD---------EDDTKFKSIPASFWWATITMTTVGYGDIYPKTLLGKIVGGL 396
Query: 336 FSLIGVSFFALPAGILGSGLALKVQEQHRQKHFEKRRK 373
+ GV ALP I+ + + +EQ RQ+ KRR+
Sbjct: 397 CCIAGVLVIALPIPIIVNNFSEFYKEQKRQEKAIKRRE 434
>gi|4826786 Shaw-related voltage-gated potassium channel protein 1
isoform B [Homo sapiens]
Length = 511
Score = 78.2 bits (191), Expect = 3e-14
Identities = 53/233 (22%), Positives = 107/233 (45%), Gaps = 15/233 (6%)
Query: 145 FKEYETVSGDWLLLLETFAIFIFGAEFALRIWAAGCCCRYKGWRGRLKFARKPLCMLDIF 204
++E ET + +L +E + F EF +R+ C K ++F + L ++D
Sbjct: 236 YREAETEA--FLTYIEGVCVVWFTFEFLMRV----IFCPNK-----VEFIKNSLNIIDFV 284
Query: 205 VLIASVPVVAVGNQGNVLATS----LRSLRFLQILRMLRMDRRGGTWKLLGSAICAHSKE 260
++ V + + A LR +RF++ILR+ ++ R ++LG + A + E
Sbjct: 285 AILPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNE 344
Query: 261 LITAWYIGFLTLILSSFLVYLVEKDVPEVDAQGEEMKEEFETYADALWWGLITLATIGYG 320
+ L +++ + ++Y E+ + + F+ WW ++T+ T+GYG
Sbjct: 345 FLLLIIFLALGVLIFATMIYYAERIGAQPNDPSASEHTHFKNIPIGFWWAVVTMTTLGYG 404
Query: 321 DKTPKTWEGRLIAATFSLIGVSFFALPAGILGSGLALKVQEQHRQKHFEKRRK 373
D P+TW G L+ A +L GV A+P ++ + + ++ K++K
Sbjct: 405 DMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKKK 457
>gi|163792201 Shaw-related voltage-gated potassium channel protein 1
isoform A [Homo sapiens]
Length = 585
Score = 78.2 bits (191), Expect = 3e-14
Identities = 53/233 (22%), Positives = 107/233 (45%), Gaps = 15/233 (6%)
Query: 145 FKEYETVSGDWLLLLETFAIFIFGAEFALRIWAAGCCCRYKGWRGRLKFARKPLCMLDIF 204
++E ET + +L +E + F EF +R+ C K ++F + L ++D
Sbjct: 236 YREAETEA--FLTYIEGVCVVWFTFEFLMRV----IFCPNK-----VEFIKNSLNIIDFV 284
Query: 205 VLIASVPVVAVGNQGNVLATS----LRSLRFLQILRMLRMDRRGGTWKLLGSAICAHSKE 260
++ V + + A LR +RF++ILR+ ++ R ++LG + A + E
Sbjct: 285 AILPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNE 344
Query: 261 LITAWYIGFLTLILSSFLVYLVEKDVPEVDAQGEEMKEEFETYADALWWGLITLATIGYG 320
+ L +++ + ++Y E+ + + F+ WW ++T+ T+GYG
Sbjct: 345 FLLLIIFLALGVLIFATMIYYAERIGAQPNDPSASEHTHFKNIPIGFWWAVVTMTTLGYG 404
Query: 321 DKTPKTWEGRLIAATFSLIGVSFFALPAGILGSGLALKVQEQHRQKHFEKRRK 373
D P+TW G L+ A +L GV A+P ++ + + ++ K++K
Sbjct: 405 DMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKKK 457
>gi|5031819 potassium voltage-gated channel, shaker-related
subfamily, member 10 [Homo sapiens]
Length = 511
Score = 78.2 bits (191), Expect = 3e-14
Identities = 45/161 (27%), Positives = 77/161 (47%), Gaps = 12/161 (7%)
Query: 218 QGNVLATSLRSLRFLQILRMLRMDRRGGTWKLLGSAICAHSKELITAWYIGFLTLILSSF 277
Q N+ LR +R +++ R+ ++ R ++LG + A +EL + F+ +IL S
Sbjct: 332 QQNMSLAILRIIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSS 391
Query: 278 LVYLVEKDVPEVDAQGEEMKEEFETYADALWWGLITLATIGYGDKTPKTWEGRLIAATFS 337
VY E D PE F + D WW ++T+ T+GYGD P T G+++ +
Sbjct: 392 AVYFAEVDEPE---------SHFSSIPDGFWWAVVTMTTVGYGDMCPTTPGGKIVGTLCA 442
Query: 338 LIGVSFFALPAGILGSGLALKVQEQHRQKHFEKRRKPAAEL 378
+ GV ALP ++ S HR+ E+++ E+
Sbjct: 443 IAGVLTIALPVPVIVSNFN---YFYHRETENEEKQNIPGEI 480
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.136 0.408
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 36,676,410
Number of Sequences: 37866
Number of extensions: 1888873
Number of successful extensions: 18548
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 318
Number of HSP's successfully gapped in prelim test: 159
Number of HSP's that attempted gapping in prelim test: 11853
Number of HSP's gapped (non-prelim): 3890
length of query: 872
length of database: 18,247,518
effective HSP length: 111
effective length of query: 761
effective length of database: 14,044,392
effective search space: 10687782312
effective search space used: 10687782312
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.