Guide to the Human Genome
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Search of human proteins with 4758436

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4758436 gastric inhibitory polypeptide preproprotein [Homo
sapiens]
         (153 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4758436 gastric inhibitory polypeptide preproprotein [Homo sa...   305   1e-83
gi|4503945 glucagon preproprotein [Homo sapiens]                       45   3e-05
gi|194294523 intersectin 2 isoform 3 [Homo sapiens]                    31   0.36 
gi|194294521 intersectin 2 isoform 1 [Homo sapiens]                    31   0.36 
gi|194294525 intersectin 2 isoform 2 [Homo sapiens]                    31   0.36 
gi|31324577 molecule interacting with Rab13 [Homo sapiens]             30   0.62 
gi|33620755 YEATS domain containing 2 [Homo sapiens]                   30   1.1  
gi|23397642 GREB1 protein isoform a [Homo sapiens]                     29   1.4  
gi|157738619 smoothelin-like 1 [Homo sapiens]                          29   1.4  
gi|4757900 calreticulin precursor [Homo sapiens]                       28   2.3  
gi|55741709 RNA binding motif protein 25 [Homo sapiens]                28   3.1  
gi|239757254 PREDICTED: hypothetical protein [Homo sapiens]            28   4.0  
gi|21361684 G patch domain containing 1 [Homo sapiens]                 28   4.0  
gi|223278381 ribosomal RNA processing 12 homolog isoform 2 [Homo...    27   5.2  
gi|223278379 ribosomal RNA processing 12 homolog isoform 1 [Homo...    27   5.2  
gi|41872631 fatty acid synthase [Homo sapiens]                         27   5.2  
gi|64276808 ADAM metallopeptidase with thrombospondin type 1 mot...    27   5.2  
gi|9951927 adducin 3 (gamma) isoform b [Homo sapiens]                  27   6.8  
gi|62912453 adducin 3 (gamma) isoform b [Homo sapiens]                 27   6.8  
gi|9943848 adducin 3 (gamma) isoform a [Homo sapiens]                  27   6.8  
gi|17402882 deoxyribonuclease II beta isoform 2 [Homo sapiens]         27   6.8  
gi|194473657 deoxyribonuclease II beta isoform 1 precursor [Homo...    27   6.8  
gi|87116683 proline/serine-rich coiled-coil 2 [Homo sapiens]           27   6.8  
gi|148806908 fibronectin type III domain containing 1 [Homo sapi...    27   8.9  
gi|33356174 pinin, desmosome associated protein [Homo sapiens]         27   8.9  
gi|104526627 triadin [Homo sapiens]                                    27   8.9  
gi|32567784 T-box 10 [Homo sapiens]                                    27   8.9  

>gi|4758436 gastric inhibitory polypeptide preproprotein [Homo
           sapiens]
          Length = 153

 Score =  305 bits (781), Expect = 1e-83
 Identities = 153/153 (100%), Positives = 153/153 (100%)

Query: 1   MVATKTFALLLLSLFLAVGLGEKKEGHFSALPSLPVGSHAKVSSPQPRGPRYAEGTFISD 60
           MVATKTFALLLLSLFLAVGLGEKKEGHFSALPSLPVGSHAKVSSPQPRGPRYAEGTFISD
Sbjct: 1   MVATKTFALLLLSLFLAVGLGEKKEGHFSALPSLPVGSHAKVSSPQPRGPRYAEGTFISD 60

Query: 61  YSIAMDKIHQQDFVNWLLAQKGKKNDWKHNITQREARALELASQANRKEEEAVEPQSSPA 120
           YSIAMDKIHQQDFVNWLLAQKGKKNDWKHNITQREARALELASQANRKEEEAVEPQSSPA
Sbjct: 61  YSIAMDKIHQQDFVNWLLAQKGKKNDWKHNITQREARALELASQANRKEEEAVEPQSSPA 120

Query: 121 KNPSDEDLLRDLLIQELLACLLDQTNLCRLRSR 153
           KNPSDEDLLRDLLIQELLACLLDQTNLCRLRSR
Sbjct: 121 KNPSDEDLLRDLLIQELLACLLDQTNLCRLRSR 153


>gi|4503945 glucagon preproprotein [Homo sapiens]
          Length = 180

 Score = 44.7 bits (104), Expect = 3e-05
 Identities = 28/95 (29%), Positives = 50/95 (52%), Gaps = 6/95 (6%)

Query: 22  EKKEGHFSALPSLPVGSHAKVSSPQPRGPRYAEGTFISDYSIAMDKIHQQDFVNWLLAQK 81
           E+K   FSA  + P+    +++  +    R+++GTF SDYS  +D    QDFV WL+  K
Sbjct: 27  EEKSRSFSASQADPLSDPDQMNEDK----RHSQGTFTSDYSKYLDSRRAQDFVQWLMNTK 82

Query: 82  GKKND--WKHNITQREARALELASQANRKEEEAVE 114
             +N+   +H+  +R A     +  ++  E +A +
Sbjct: 83  RNRNNIAKRHDEFERHAEGTFTSDVSSYLEGQAAK 117



 Score = 34.7 bits (78), Expect = 0.033
 Identities = 13/41 (31%), Positives = 26/41 (63%)

Query: 41  KVSSPQPRGPRYAEGTFISDYSIAMDKIHQQDFVNWLLAQK 81
           +V+  +  G R+A+G+F  + +  +D +  +DF+NWL+  K
Sbjct: 135 EVAIVEELGRRHADGSFSDEMNTILDNLAARDFINWLIQTK 175



 Score = 32.7 bits (73), Expect = 0.12
 Identities = 13/35 (37%), Positives = 24/35 (68%)

Query: 51  RYAEGTFISDYSIAMDKIHQQDFVNWLLAQKGKKN 85
           R+AEGTF SD S  ++    ++F+ WL+  +G+++
Sbjct: 97  RHAEGTFTSDVSSYLEGQAAKEFIAWLVKGRGRRD 131


>gi|194294523 intersectin 2 isoform 3 [Homo sapiens]
          Length = 1670

 Score = 31.2 bits (69), Expect = 0.36
 Identities = 14/52 (26%), Positives = 27/52 (51%)

Query: 79  AQKGKKNDWKHNITQREARALELASQANRKEEEAVEPQSSPAKNPSDEDLLR 130
           A++GK+N WK N+ + E    +   +   +E+   E + +  K   D+D L+
Sbjct: 669 AKQGKENLWKENLRKEEEEKQKRLQEEKTQEKIQEEERKAEEKQRKDKDTLK 720


>gi|194294521 intersectin 2 isoform 1 [Homo sapiens]
          Length = 1697

 Score = 31.2 bits (69), Expect = 0.36
 Identities = 14/52 (26%), Positives = 27/52 (51%)

Query: 79  AQKGKKNDWKHNITQREARALELASQANRKEEEAVEPQSSPAKNPSDEDLLR 130
           A++GK+N WK N+ + E    +   +   +E+   E + +  K   D+D L+
Sbjct: 696 AKQGKENLWKENLRKEEEEKQKRLQEEKTQEKIQEEERKAEEKQRKDKDTLK 747


>gi|194294525 intersectin 2 isoform 2 [Homo sapiens]
          Length = 1249

 Score = 31.2 bits (69), Expect = 0.36
 Identities = 14/52 (26%), Positives = 27/52 (51%)

Query: 79  AQKGKKNDWKHNITQREARALELASQANRKEEEAVEPQSSPAKNPSDEDLLR 130
           A++GK+N WK N+ + E    +   +   +E+   E + +  K   D+D L+
Sbjct: 696 AKQGKENLWKENLRKEEEEKQKRLQEEKTQEKIQEEERKAEEKQRKDKDTLK 747


>gi|31324577 molecule interacting with Rab13 [Homo sapiens]
          Length = 863

 Score = 30.4 bits (67), Expect = 0.62
 Identities = 18/65 (27%), Positives = 37/65 (56%), Gaps = 6/65 (9%)

Query: 88  KHNITQREARALELASQANRKEEEA-VEPQ-----SSPAKNPSDEDLLRDLLIQELLACL 141
           KH + +RE+  + +  Q N ++ +A VE +     + P K+ ++ED  R+ ++ + L  L
Sbjct: 732 KHLLVRRESELIYVFKQQNLEQRQADVEYELRCLLNKPEKDWTEEDRAREKVLMQELVTL 791

Query: 142 LDQTN 146
           ++Q N
Sbjct: 792 IEQRN 796


>gi|33620755 YEATS domain containing 2 [Homo sapiens]
          Length = 1422

 Score = 29.6 bits (65), Expect = 1.1
 Identities = 12/27 (44%), Positives = 21/27 (77%), Gaps = 1/27 (3%)

Query: 22  EKKEGHFSALPSL-PVGSHAKVSSPQP 47
           ++++  F+++P L P+GSH KV SP+P
Sbjct: 552 KQEDSLFASMPPLCPIGSHPKVQSPKP 578


>gi|23397642 GREB1 protein isoform a [Homo sapiens]
          Length = 1949

 Score = 29.3 bits (64), Expect = 1.4
 Identities = 17/31 (54%), Positives = 19/31 (61%), Gaps = 3/31 (9%)

Query: 21   GEKKEGHFSALPS-LPVGSHAKVSSPQPRGP 50
            G    G  SA P+ LP G HA+  SPQPRGP
Sbjct: 1138 GSALGGESSAQPTALPQGEHAR--SPQPRGP 1166


>gi|157738619 smoothelin-like 1 [Homo sapiens]
          Length = 512

 Score = 29.3 bits (64), Expect = 1.4
 Identities = 13/46 (28%), Positives = 24/46 (52%)

Query: 82  GKKNDWKHNITQREARALELASQANRKEEEAVEPQSSPAKNPSDED 127
           G+K + K    + E +   LAS+  + EE+  +P+S    + +D D
Sbjct: 131 GRKEETKSEPKEAEEKESTLASEKQKAEEKEAKPESGQKADANDRD 176


>gi|4757900 calreticulin precursor [Homo sapiens]
          Length = 417

 Score = 28.5 bits (62), Expect = 2.3
 Identities = 19/75 (25%), Positives = 31/75 (41%), Gaps = 4/75 (5%)

Query: 55  GTFISDYSIAMDKIHQQDFVN--WLLAQKGKKNDWKHNITQREARALELASQANRKEEEA 112
           GT   ++ I  D+ + ++F N  W + +  +K     +    E R  E      RKEEE 
Sbjct: 324 GTIFDNFLITNDEAYAEEFGNETWGVTKAAEKQ--MKDKQDEEQRLKEEEEDKKRKEEEE 381

Query: 113 VEPQSSPAKNPSDED 127
            E +        DE+
Sbjct: 382 AEDKEDDEDKDEDEE 396


>gi|55741709 RNA binding motif protein 25 [Homo sapiens]
          Length = 843

 Score = 28.1 bits (61), Expect = 3.1
 Identities = 11/42 (26%), Positives = 23/42 (54%)

Query: 69  HQQDFVNWLLAQKGKKNDWKHNITQREARALELASQANRKEE 110
           +Q+   NW + ++ K  +++    + E R  E+A +A R +E
Sbjct: 457 YQERLKNWEIRERKKTREYEKEAEREEERRREMAKEAKRLKE 498


>gi|239757254 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 247

 Score = 27.7 bits (60), Expect = 4.0
 Identities = 12/22 (54%), Positives = 15/22 (68%)

Query: 29  SALPSLPVGSHAKVSSPQPRGP 50
           ++L SLP GSH    SP+PR P
Sbjct: 79  ASLLSLPYGSHRHPPSPRPRDP 100


>gi|21361684 G patch domain containing 1 [Homo sapiens]
          Length = 931

 Score = 27.7 bits (60), Expect = 4.0
 Identities = 19/69 (27%), Positives = 30/69 (43%), Gaps = 10/69 (14%)

Query: 80  QKGKKNDWKHNITQREARALE----------LASQANRKEEEAVEPQSSPAKNPSDEDLL 129
           +K KKN  KH   +   R  E             Q N+K E++   +SS + +   ++  
Sbjct: 852 EKHKKNKDKHKAKKEHRRKKEKKKKHRKHKHKGKQKNKKPEKSSSSESSDSSDSQSDEET 911

Query: 130 RDLLIQELL 138
            D+  QELL
Sbjct: 912 ADVSPQELL 920


>gi|223278381 ribosomal RNA processing 12 homolog isoform 2 [Homo
            sapiens]
          Length = 1236

 Score = 27.3 bits (59), Expect = 5.2
 Identities = 19/46 (41%), Positives = 25/46 (54%), Gaps = 4/46 (8%)

Query: 90   NITQREARALE--LASQANRKEEEAVEPQSSPAKNPSD--EDLLRD 131
            NI + EARA      SQA  +EEE  E +  PA+   D  E++L D
Sbjct: 973  NIRKAEARAKRHRALSQAAVEEEEEEEEEEEPAQGKGDSIEEILAD 1018


>gi|223278379 ribosomal RNA processing 12 homolog isoform 1 [Homo
            sapiens]
          Length = 1297

 Score = 27.3 bits (59), Expect = 5.2
 Identities = 19/46 (41%), Positives = 25/46 (54%), Gaps = 4/46 (8%)

Query: 90   NITQREARALE--LASQANRKEEEAVEPQSSPAKNPSD--EDLLRD 131
            NI + EARA      SQA  +EEE  E +  PA+   D  E++L D
Sbjct: 1034 NIRKAEARAKRHRALSQAAVEEEEEEEEEEEPAQGKGDSIEEILAD 1079


>gi|41872631 fatty acid synthase [Homo sapiens]
          Length = 2511

 Score = 27.3 bits (59), Expect = 5.2
 Identities = 21/64 (32%), Positives = 27/64 (42%), Gaps = 4/64 (6%)

Query: 12  LSLFLAVGLGEKKEGHFSALPSLPVGSHAKVSSPQPRGPRYAEGTFISDYSIAMDKIHQQ 71
           L  FLA G+G     H S + + P      V  P PRG          D+S+A D    +
Sbjct: 793 LEFFLA-GIGRL---HLSGIDANPNALFPPVEFPAPRGTPLISPLIKWDHSLAWDVPAAE 848

Query: 72  DFVN 75
           DF N
Sbjct: 849 DFPN 852


>gi|64276808 ADAM metallopeptidase with thrombospondin type 1 motif,
           6 preproprotein [Homo sapiens]
          Length = 1117

 Score = 27.3 bits (59), Expect = 5.2
 Identities = 33/114 (28%), Positives = 52/114 (45%), Gaps = 18/114 (15%)

Query: 25  EGHFSALPSLPVGSHAKVSSPQPRGPRYAEGTFISDYSIAMDKIHQQDFVNWLLAQKGKK 84
           EG F+   SLP G + +V    PRG  + E        +AM K +        +A K + 
Sbjct: 720 EGFFN--DSLPRGGYMEVVQI-PRGSVHIEVR-----EVAMSKNY--------IALKSEG 763

Query: 85  NDWKHN--ITQREARALELASQANRKEEEAVEPQSSPAKNPSDEDLLRDLLIQE 136
           +D+  N   T    R  ++A  A   +    EP+S  A  P+ E+L+  +L+QE
Sbjct: 764 DDYYINGAWTIDWPRKFDVAGTAFHYKRPTDEPESLEALGPTSENLIVMVLLQE 817


>gi|9951927 adducin 3 (gamma) isoform b [Homo sapiens]
          Length = 674

 Score = 26.9 bits (58), Expect = 6.8
 Identities = 10/26 (38%), Positives = 18/26 (69%)

Query: 99  LELASQANRKEEEAVEPQSSPAKNPS 124
           +E+  ++  K EE + P+ SP+K+PS
Sbjct: 626 IEITIKSPEKIEEVLSPEGSPSKSPS 651


>gi|62912453 adducin 3 (gamma) isoform b [Homo sapiens]
          Length = 674

 Score = 26.9 bits (58), Expect = 6.8
 Identities = 10/26 (38%), Positives = 18/26 (69%)

Query: 99  LELASQANRKEEEAVEPQSSPAKNPS 124
           +E+  ++  K EE + P+ SP+K+PS
Sbjct: 626 IEITIKSPEKIEEVLSPEGSPSKSPS 651


>gi|9943848 adducin 3 (gamma) isoform a [Homo sapiens]
          Length = 706

 Score = 26.9 bits (58), Expect = 6.8
 Identities = 10/26 (38%), Positives = 18/26 (69%)

Query: 99  LELASQANRKEEEAVEPQSSPAKNPS 124
           +E+  ++  K EE + P+ SP+K+PS
Sbjct: 658 IEITIKSPEKIEEVLSPEGSPSKSPS 683


>gi|17402882 deoxyribonuclease II beta isoform 2 [Homo sapiens]
          Length = 153

 Score = 26.9 bits (58), Expect = 6.8
 Identities = 9/17 (52%), Positives = 11/17 (64%)

Query: 71  QDFVNWLLAQKGKKNDW 87
           QD   W ++QKG KN W
Sbjct: 95  QDHAKWCISQKGTKNRW 111


>gi|194473657 deoxyribonuclease II beta isoform 1 precursor [Homo
           sapiens]
          Length = 361

 Score = 26.9 bits (58), Expect = 6.8
 Identities = 9/17 (52%), Positives = 11/17 (64%)

Query: 71  QDFVNWLLAQKGKKNDW 87
           QD   W ++QKG KN W
Sbjct: 303 QDHAKWCISQKGTKNRW 319


>gi|87116683 proline/serine-rich coiled-coil 2 [Homo sapiens]
          Length = 1989

 Score = 26.9 bits (58), Expect = 6.8
 Identities = 14/34 (41%), Positives = 18/34 (52%)

Query: 26  GHFSALPSLPVGSHAKVSSPQPRGPRYAEGTFIS 59
           G+FS  PSL +    +VSS  P    Y EG  +S
Sbjct: 558 GYFSPAPSLSLPPPPQVSSLPPLSQPYVEGLCVS 591


>gi|148806908 fibronectin type III domain containing 1 [Homo
           sapiens]
          Length = 1894

 Score = 26.6 bits (57), Expect = 8.9
 Identities = 28/101 (27%), Positives = 37/101 (36%), Gaps = 11/101 (10%)

Query: 32  PSLPVGSHAKVSSPQPRGPRYAEGTFISDYSIAMDKIHQQDFVNWLLAQKGKKNDWKHNI 91
           PS P    A  SS  P  P   +G    D  +        D  N +LA  G     K  +
Sbjct: 477 PSSP-SPRAPASSQHPSVPASPQGRNAKDLLL--------DLKNKILANGGAPR--KPQL 525

Query: 92  TQREARALELASQANRKEEEAVEPQSSPAKNPSDEDLLRDL 132
             ++A  L+L S     EEE    + SP      +D  R L
Sbjct: 526 RAKKAEELDLQSTEITGEEELGSREDSPMSPSDTQDQKRTL 566


>gi|33356174 pinin, desmosome associated protein [Homo sapiens]
          Length = 717

 Score = 26.6 bits (57), Expect = 8.9
 Identities = 10/29 (34%), Positives = 16/29 (55%)

Query: 98  ALELASQANRKEEEAVEPQSSPAKNPSDE 126
           AL++  ++  KEE+  EPQ  P   P  +
Sbjct: 451 ALDMEKESEEKEEKESEPQPEPVAQPQPQ 479


>gi|104526627 triadin [Homo sapiens]
          Length = 729

 Score = 26.6 bits (57), Expect = 8.9
 Identities = 17/58 (29%), Positives = 28/58 (48%), Gaps = 6/58 (10%)

Query: 77  LLAQKGKKNDWKHNITQREARALELASQANRKEEEA---VEPQSSPAKN---PSDEDL 128
           + AQ   K D K   +++  +  E+     +K+E+    VEP  SP K    PSD+ +
Sbjct: 365 IAAQAAAKKDEKKEDSKKTKKPAEVEQPKGKKQEKKEKHVEPAKSPKKEHSVPSDKQV 422


>gi|32567784 T-box 10 [Homo sapiens]
          Length = 385

 Score = 26.6 bits (57), Expect = 8.9
 Identities = 13/39 (33%), Positives = 19/39 (48%)

Query: 12 LSLFLAVGLGEKKEGHFSALPSLPVGSHAKVSSPQPRGP 50
          ++ FL+ GLG         LP+   G   ++ SP P GP
Sbjct: 1  MAAFLSAGLGILAPSETYPLPTTSSGWEPRLGSPFPSGP 39


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.131    0.377 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 6,053,853
Number of Sequences: 37866
Number of extensions: 264627
Number of successful extensions: 1254
Number of sequences better than 10.0: 27
Number of HSP's better than 10.0 without gapping: 17
Number of HSP's successfully gapped in prelim test: 10
Number of HSP's that attempted gapping in prelim test: 1229
Number of HSP's gapped (non-prelim): 33
length of query: 153
length of database: 18,247,518
effective HSP length: 93
effective length of query: 60
effective length of database: 14,725,980
effective search space: 883558800
effective search space used: 883558800
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 57 (26.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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