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Search of human proteins with 4758378
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4758378 vascular endothelial growth factor D preproprotein
[Homo sapiens]
(354 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4758378 vascular endothelial growth factor D preproprotein [H... 760 0.0
gi|4885653 vascular endothelial growth factor C preproprotein [H... 258 4e-69
gi|76781480 vascular endothelial growth factor A isoform a precu... 70 2e-12
gi|76781482 vascular endothelial growth factor A isoform c precu... 69 5e-12
gi|76781484 vascular endothelial growth factor A isoform e precu... 69 6e-12
gi|76781483 vascular endothelial growth factor A isoform d precu... 69 6e-12
gi|76781481 vascular endothelial growth factor A isoform b precu... 69 6e-12
gi|76781487 vascular endothelial growth factor A isoform g precu... 69 6e-12
gi|76781485 vascular endothelial growth factor A isoform f precu... 68 1e-11
gi|20149543 placental growth factor, vascular endothelial growth... 65 7e-11
gi|4507887 vascular endothelial growth factor B [Homo sapiens] 60 4e-09
gi|9994187 platelet-derived growth factor C precursor [Homo sapi... 54 2e-07
gi|15451786 platelet-derived growth factor beta isoform 2 prepro... 51 1e-06
gi|4505681 platelet-derived growth factor beta isoform 1 preprop... 51 1e-06
gi|15208656 platelet-derived growth factor alpha isoform 2 prepr... 46 6e-05
gi|77695917 platelet-derived growth factor alpha isoform 1 prepr... 46 6e-05
gi|13376808 platelet derived growth factor D isoform 1 precursor... 42 0.001
gi|15451921 platelet derived growth factor D isoform 2 precursor... 42 0.001
gi|54292117 ADAM metallopeptidase domain 28 isoform 3 preproprot... 34 0.17
gi|98985828 ADAM metallopeptidase domain 28 isoform 1 preproprot... 34 0.17
gi|89363020 nuclear transcription factor, X-box binding-like 1 [... 34 0.17
gi|122937257 thrombospondin, type I, domain containing 7B [Homo ... 34 0.23
gi|33598931 scavenger receptor class F, member 1 isoform 3 precu... 33 0.30
gi|33598929 scavenger receptor class F, member 1 isoform 1 precu... 33 0.30
gi|145309306 scavenger receptor class F, member 1 isoform 5 prec... 33 0.30
gi|22212927 nuclear transcription factor, X-box binding 1 isofor... 33 0.30
gi|20336246 proprotein convertase subtilisin/kexin type 5 prepro... 33 0.30
gi|58082087 late cornified envelope-like proline-rich 1 [Homo sa... 33 0.51
gi|22212925 nuclear transcription factor, X-box binding 1 isofor... 32 0.66
gi|21361137 nuclear transcription factor, X-box binding 1 isofor... 32 0.66
>gi|4758378 vascular endothelial growth factor D preproprotein [Homo
sapiens]
Length = 354
Score = 760 bits (1963), Expect = 0.0
Identities = 354/354 (100%), Positives = 354/354 (100%)
Query: 1 MYREWVVVNVFMMLYVQLVQGSSNEHGPVKRSSQSTLERSEQQIRAASSLEELLRITHSE 60
MYREWVVVNVFMMLYVQLVQGSSNEHGPVKRSSQSTLERSEQQIRAASSLEELLRITHSE
Sbjct: 1 MYREWVVVNVFMMLYVQLVQGSSNEHGPVKRSSQSTLERSEQQIRAASSLEELLRITHSE 60
Query: 61 DWKLWRCRLRLKSFTSMDSRSASHRSTRFAATFYDIETLKVIDEEWQRTQCSPRETCVEV 120
DWKLWRCRLRLKSFTSMDSRSASHRSTRFAATFYDIETLKVIDEEWQRTQCSPRETCVEV
Sbjct: 61 DWKLWRCRLRLKSFTSMDSRSASHRSTRFAATFYDIETLKVIDEEWQRTQCSPRETCVEV 120
Query: 121 ASELGKSTNTFFKPPCVNVFRCGGCCNEESLICMNTSTSYISKQLFEISVPLTSVPELVP 180
ASELGKSTNTFFKPPCVNVFRCGGCCNEESLICMNTSTSYISKQLFEISVPLTSVPELVP
Sbjct: 121 ASELGKSTNTFFKPPCVNVFRCGGCCNEESLICMNTSTSYISKQLFEISVPLTSVPELVP 180
Query: 181 VKVANHTGCKCLPTAPRHPYSIIRRSIQIPEEDRCSHSKKLCPIDMLWDSNKCKCVLQEE 240
VKVANHTGCKCLPTAPRHPYSIIRRSIQIPEEDRCSHSKKLCPIDMLWDSNKCKCVLQEE
Sbjct: 181 VKVANHTGCKCLPTAPRHPYSIIRRSIQIPEEDRCSHSKKLCPIDMLWDSNKCKCVLQEE 240
Query: 241 NPLAGTEDHSHLQEPALCGPHMMFDEDRCECVCKTPCPKDLIQHPKNCSCFECKESLETC 300
NPLAGTEDHSHLQEPALCGPHMMFDEDRCECVCKTPCPKDLIQHPKNCSCFECKESLETC
Sbjct: 241 NPLAGTEDHSHLQEPALCGPHMMFDEDRCECVCKTPCPKDLIQHPKNCSCFECKESLETC 300
Query: 301 CQKHKLFHPDTCSCEDRCPFHTRPCASGKTACAKHCRFPKEKRAAQGPHSRKNP 354
CQKHKLFHPDTCSCEDRCPFHTRPCASGKTACAKHCRFPKEKRAAQGPHSRKNP
Sbjct: 301 CQKHKLFHPDTCSCEDRCPFHTRPCASGKTACAKHCRFPKEKRAAQGPHSRKNP 354
>gi|4885653 vascular endothelial growth factor C preproprotein [Homo
sapiens]
Length = 419
Score = 258 bits (660), Expect = 4e-69
Identities = 139/358 (38%), Positives = 199/358 (55%), Gaps = 67/358 (18%)
Query: 41 EQQIRAASSLEELLRITHSEDWKLWRCRLRLKSFT----SMDSRSASHRSTRFAATFYDI 96
E+Q+R+ SS++EL+ + + E WK+++C+LR + + S + + +FAA Y+
Sbjct: 57 EEQLRSVSSVDELMTVLYPEYWKMYKCQLRKGGWQHNREQANLNSRTEETIKFAAAHYNT 116
Query: 97 ETLKVIDEEWQRTQCSPRETCVEVASELGKSTNTFFKPPCVNVFRCGGCCNEESLICMNT 156
E LK ID EW++TQC PRE C++V E G +TNTFFKPPCV+V+RCGGCCN E L CMNT
Sbjct: 117 EILKSIDNEWRKTQCMPREVCIDVGKEFGVATNTFFKPPCVSVYRCGGCCNSEGLQCMNT 176
Query: 157 STSYISKQLFEISVPLTSVPELVPVKVANHTGCKCLPTAP--RHPYSIIRRSI--QIPEE 212
STSY+SK LFEI+VPL+ P+ V + ANHT C+C+ R +SIIRRS+ +P+
Sbjct: 177 STSYLSKTLFEITVPLSQGPKPVTISFANHTSCRCMSKLDVYRQVHSIIRRSLPATLPQ- 235
Query: 213 DRCSHSKKLCPIDMLWDSNKCKCVLQEE---NPLAGTED----------HSHLQE----- 254
C + K CP + +W+++ C+C+ QE+ + AG + + L E
Sbjct: 236 --CQAANKTCPTNYMWNNHICRCLAQEDFMFSSDAGDDSTDGFHDICGPNKELDEETCQC 293
Query: 255 -------PALCGPH------------------------MMFDEDRCECVCKTPCPKDLIQ 283
PA CGPH FDE+ C+CVCK CP++
Sbjct: 294 VCRAGLRPASCGPHKELDRNSCQCVCKNKLFPSQCGANREFDENTCQCVCKRTCPRNQPL 353
Query: 284 HPKNCSCFECKESLETCCQKHKLFHPDTCSCEDRCPFHTRPCASGKTACAKHCRFPKE 341
+P C+C EC ES + C K K FH TCSC + RPC + + AC + +E
Sbjct: 354 NPGKCAC-ECTESPQKCLLKGKKFHHQTCSC------YRRPCTNRQKACEPGFSYSEE 404
>gi|76781480 vascular endothelial growth factor A isoform a
precursor [Homo sapiens]
Length = 412
Score = 70.5 bits (171), Expect = 2e-12
Identities = 58/220 (26%), Positives = 86/220 (39%), Gaps = 31/220 (14%)
Query: 97 ETLKVIDEEWQRTQCSPRETCVEVASELGKSTNTFFKPPCVNVFRCGGCCNEESLICMNT 156
E +K +D +QR+ C P ET V++ E FKP CV + RCGGCCN+E L C+ T
Sbjct: 219 EVVKFMDV-YQRSYCHPIETLVDIFQEYPDEIEYIFKPSCVPLMRCGGCCNDEGLECVPT 277
Query: 157 STSYISKQLFEISVPLTSVPELVPVKVANHTGCKCLPTAPRHPYSIIRRSIQIPEEDRCS 216
S I+ Q+ I + + H C+C P R ++S++ + +
Sbjct: 278 EESNITMQIMRIKP--HQGQHIGEMSFLQHNKCECRPKKDRARQE--KKSVRGKGKGQKR 333
Query: 217 HSKKLCPIDMLWDSN-KCKCVLQEENPLAGTEDHSHLQEPALCGPHMMFDEDRCECVCKT 275
KK W +C L + L P CGP C
Sbjct: 334 KRKK--SRYKSWSVYVGARCCLMPWS----------LPGPHPCGP------------CSE 369
Query: 276 PCPKDLIQHPKNCSCFECKESLETCCQKHKLFHPDTCSCE 315
+Q P+ C C CK + C + + TC C+
Sbjct: 370 RRKHLFVQDPQTCKC-SCKNTDSRCKARQLELNERTCRCD 408
>gi|76781482 vascular endothelial growth factor A isoform c
precursor [Homo sapiens]
Length = 389
Score = 69.3 bits (168), Expect = 5e-12
Identities = 50/194 (25%), Positives = 78/194 (40%), Gaps = 28/194 (14%)
Query: 97 ETLKVIDEEWQRTQCSPRETCVEVASELGKSTNTFFKPPCVNVFRCGGCCNEESLICMNT 156
E +K +D +QR+ C P ET V++ E FKP CV + RCGGCCN+E L C+ T
Sbjct: 219 EVVKFMDV-YQRSYCHPIETLVDIFQEYPDEIEYIFKPSCVPLMRCGGCCNDEGLECVPT 277
Query: 157 STSYISKQLFEISVPLTSVPELVPVKVANHTGCKCLPTAPRHPYSIIRRSIQIPEEDRCS 216
S I+ Q+ I + + H C+C P R ++S++ + +
Sbjct: 278 EESNITMQIMRIKP--HQGQHIGEMSFLQHNKCECRPKKDRARQE--KKSVRGKGKGQKR 333
Query: 217 HSKKLCPIDMLWDSNKCKCVLQEENPLAGTEDHSHLQEPALCGPHMMFDEDRCECVCKTP 276
KK P P + H +Q+P C + RC+
Sbjct: 334 KRKKSRPC----------------GPCSERRKHLFVQDPQTCKCSCKNTDSRCKA----- 372
Query: 277 CPKDLIQHPKNCSC 290
+ L + + C C
Sbjct: 373 --RQLELNERTCRC 384
>gi|76781484 vascular endothelial growth factor A isoform e
precursor [Homo sapiens]
Length = 354
Score = 68.9 bits (167), Expect = 6e-12
Identities = 42/131 (32%), Positives = 60/131 (45%), Gaps = 10/131 (7%)
Query: 97 ETLKVIDEEWQRTQCSPRETCVEVASELGKSTNTFFKPPCVNVFRCGGCCNEESLICMNT 156
E +K +D +QR+ C P ET V++ E FKP CV + RCGGCCN+E L C+ T
Sbjct: 219 EVVKFMDV-YQRSYCHPIETLVDIFQEYPDEIEYIFKPSCVPLMRCGGCCNDEGLECVPT 277
Query: 157 STSYISKQLFEISVPLTSVPELVPVKVANHTGCKCLPTA-------PRHPYSIIRRSIQI 209
S I+ Q+ I + + H C+C P P P S R+ + +
Sbjct: 278 EESNITMQIMRIKP--HQGQHIGEMSFLQHNKCECRPKKDRARQENPCGPCSERRKHLFV 335
Query: 210 PEEDRCSHSKK 220
+ C S K
Sbjct: 336 QDPQTCKCSCK 346
>gi|76781483 vascular endothelial growth factor A isoform d
precursor [Homo sapiens]
Length = 371
Score = 68.9 bits (167), Expect = 6e-12
Identities = 42/131 (32%), Positives = 60/131 (45%), Gaps = 10/131 (7%)
Query: 97 ETLKVIDEEWQRTQCSPRETCVEVASELGKSTNTFFKPPCVNVFRCGGCCNEESLICMNT 156
E +K +D +QR+ C P ET V++ E FKP CV + RCGGCCN+E L C+ T
Sbjct: 219 EVVKFMDV-YQRSYCHPIETLVDIFQEYPDEIEYIFKPSCVPLMRCGGCCNDEGLECVPT 277
Query: 157 STSYISKQLFEISVPLTSVPELVPVKVANHTGCKCLPTA-------PRHPYSIIRRSIQI 209
S I+ Q+ I + + H C+C P P P S R+ + +
Sbjct: 278 EESNITMQIMRIKP--HQGQHIGEMSFLQHNKCECRPKKDRARQENPCGPCSERRKHLFV 335
Query: 210 PEEDRCSHSKK 220
+ C S K
Sbjct: 336 QDPQTCKCSCK 346
>gi|76781481 vascular endothelial growth factor A isoform b
precursor [Homo sapiens]
Length = 395
Score = 68.9 bits (167), Expect = 6e-12
Identities = 51/194 (26%), Positives = 80/194 (41%), Gaps = 22/194 (11%)
Query: 97 ETLKVIDEEWQRTQCSPRETCVEVASELGKSTNTFFKPPCVNVFRCGGCCNEESLICMNT 156
E +K +D +QR+ C P ET V++ E FKP CV + RCGGCCN+E L C+ T
Sbjct: 219 EVVKFMDV-YQRSYCHPIETLVDIFQEYPDEIEYIFKPSCVPLMRCGGCCNDEGLECVPT 277
Query: 157 STSYISKQLFEISVPLTSVPELVPVKVANHTGCKCLPTAPRHPYSIIRRSIQIPEEDRCS 216
S I+ Q+ I + + H C+C P R ++S++ + +
Sbjct: 278 EESNITMQIMRIKP--HQGQHIGEMSFLQHNKCECRPKKDRARQE--KKSVRGKGKGQKR 333
Query: 217 HSKKLCPIDMLWDSNKCKCVLQEENPLAGTEDHSHLQEPALCGPHMMFDEDRCECVCKTP 276
KK + S C P + H +Q+P C + RC+
Sbjct: 334 KRKK-----SRYKSWSVPC-----GPCSERRKHLFVQDPQTCKCSCKNTDSRCKA----- 378
Query: 277 CPKDLIQHPKNCSC 290
+ L + + C C
Sbjct: 379 --RQLELNERTCRC 390
>gi|76781487 vascular endothelial growth factor A isoform g
precursor [Homo sapiens]
Length = 371
Score = 68.9 bits (167), Expect = 6e-12
Identities = 42/131 (32%), Positives = 60/131 (45%), Gaps = 10/131 (7%)
Query: 97 ETLKVIDEEWQRTQCSPRETCVEVASELGKSTNTFFKPPCVNVFRCGGCCNEESLICMNT 156
E +K +D +QR+ C P ET V++ E FKP CV + RCGGCCN+E L C+ T
Sbjct: 219 EVVKFMDV-YQRSYCHPIETLVDIFQEYPDEIEYIFKPSCVPLMRCGGCCNDEGLECVPT 277
Query: 157 STSYISKQLFEISVPLTSVPELVPVKVANHTGCKCLPTA-------PRHPYSIIRRSIQI 209
S I+ Q+ I + + H C+C P P P S R+ + +
Sbjct: 278 EESNITMQIMRIKP--HQGQHIGEMSFLQHNKCECRPKKDRARQENPCGPCSERRKHLFV 335
Query: 210 PEEDRCSHSKK 220
+ C S K
Sbjct: 336 QDPQTCKCSCK 346
>gi|76781485 vascular endothelial growth factor A isoform f
precursor [Homo sapiens]
Length = 327
Score = 68.2 bits (165), Expect = 1e-11
Identities = 36/101 (35%), Positives = 50/101 (49%), Gaps = 3/101 (2%)
Query: 97 ETLKVIDEEWQRTQCSPRETCVEVASELGKSTNTFFKPPCVNVFRCGGCCNEESLICMNT 156
E +K +D +QR+ C P ET V++ E FKP CV + RCGGCCN+E L C+ T
Sbjct: 219 EVVKFMDV-YQRSYCHPIETLVDIFQEYPDEIEYIFKPSCVPLMRCGGCCNDEGLECVPT 277
Query: 157 STSYISKQLFEISVPLTSVPELVPVKVANHTGCKCLPTAPR 197
S I+ Q+ I + + H C+C P R
Sbjct: 278 EESNITMQIMRIKP--HQGQHIGEMSFLQHNKCECRPKKDR 316
>gi|20149543 placental growth factor, vascular endothelial growth
factor-related protein [Homo sapiens]
Length = 170
Score = 65.5 bits (158), Expect = 7e-11
Identities = 31/90 (34%), Positives = 45/90 (50%), Gaps = 2/90 (2%)
Query: 104 EEWQRTQCSPRETCVEVASELGKSTNTFFKPPCVNVFRCGGCCNEESLICMNTSTSYISK 163
E W R+ C E V+V SE F P CV++ RC GCC +E+L C+ T+ ++
Sbjct: 45 EVWGRSYCRALERLVDVVSEYPSEVEHMFSPSCVSLLRCTGCCGDENLHCVPVETANVTM 104
Query: 164 QLFEISVPLTSVPELVPVKVANHTGCKCLP 193
QL +I P V + + H C+C P
Sbjct: 105 QLLKIR--SGDRPSYVELTFSQHVRCECRP 132
>gi|4507887 vascular endothelial growth factor B [Homo sapiens]
Length = 207
Score = 59.7 bits (143), Expect = 4e-09
Identities = 29/88 (32%), Positives = 43/88 (48%), Gaps = 3/88 (3%)
Query: 106 WQRTQCSPRETCVEVASELGKSTNTFFKPPCVNVFRCGGCCNEESLICMNTSTSYISKQL 165
+ R C PRE V + EL + P CV V RCGGCC ++ L C+ T + Q+
Sbjct: 42 YTRATCQPREVVVPLTVELMGTVAKQLVPSCVTVQRCGGCCPDDGLECVPTGQHQVRMQI 101
Query: 166 FEISVPLTSVPELVPVKVANHTGCKCLP 193
I P + + E+ + H+ C+C P
Sbjct: 102 LMIRYPSSQLGEM---SLEEHSQCECRP 126
>gi|9994187 platelet-derived growth factor C precursor [Homo
sapiens]
Length = 345
Score = 53.9 bits (128), Expect = 2e-07
Identities = 54/193 (27%), Positives = 81/193 (41%), Gaps = 24/193 (12%)
Query: 9 NVFMMLYVQLVQGSSNEHGPVKRSSQSTLERSEQQIRAASSLEELLRITHSEDWKLWRCR 68
N+ M + + V S V S L+ I A S+LE+L+R E W+L
Sbjct: 161 NIVMPQFTEAVSPS------VLPPSALPLDLLNNAITAFSTLEDLIRYLEPERWQLDLED 214
Query: 69 LRLKSFTSMDSRSASHRSTRFAATFYDIETLKVIDEEWQRTQCSPRETCVEVASELGKST 128
L ++ + R +R + L ++ EE + C+PR V + EL K T
Sbjct: 215 LYRPTWQLLGKAFVFGRKSR-------VVDLNLLTEEVRLYSCTPRNFSVSIREEL-KRT 266
Query: 129 NTFFKPPCVNVFRCGG---CCNEESLICMNTSTSYISKQLFEISV--PLTSV----PELV 179
+T F P C+ V RCGG CC C S ++K+ E+ P T V L
Sbjct: 267 DTIFWPGCLLVKRCGGNCACCLHNCNEC-QCVPSKVTKKYHEVLQLRPKTGVRGLHKSLT 325
Query: 180 PVKVANHTGCKCL 192
V + +H C C+
Sbjct: 326 DVALEHHEECDCV 338
>gi|15451786 platelet-derived growth factor beta isoform 2
preproprotein [Homo sapiens]
Length = 226
Score = 51.2 bits (121), Expect = 1e-06
Identities = 30/93 (32%), Positives = 41/93 (44%), Gaps = 3/93 (3%)
Query: 110 QCSPRETCVEVASELGKSTNTFFK--PPCVNVFRCGGCCNEESLICMNTSTSYISKQLFE 167
+C R E++ L TN F PPCV V RC GCCN ++ C T Q+ +
Sbjct: 81 ECKTRTEVFEISRRLIDRTNANFLVWPPCVEVQRCSGCCNNRNVQCRPTQVQLRPVQVRK 140
Query: 168 IS-VPLTSVPELVPVKVANHTGCKCLPTAPRHP 199
I V + + V + +H CKC A P
Sbjct: 141 IEIVRKKPIFKKATVTLEDHLACKCETVAAARP 173
>gi|4505681 platelet-derived growth factor beta isoform 1
preproprotein [Homo sapiens]
Length = 241
Score = 51.2 bits (121), Expect = 1e-06
Identities = 30/93 (32%), Positives = 41/93 (44%), Gaps = 3/93 (3%)
Query: 110 QCSPRETCVEVASELGKSTNTFFK--PPCVNVFRCGGCCNEESLICMNTSTSYISKQLFE 167
+C R E++ L TN F PPCV V RC GCCN ++ C T Q+ +
Sbjct: 96 ECKTRTEVFEISRRLIDRTNANFLVWPPCVEVQRCSGCCNNRNVQCRPTQVQLRPVQVRK 155
Query: 168 IS-VPLTSVPELVPVKVANHTGCKCLPTAPRHP 199
I V + + V + +H CKC A P
Sbjct: 156 IEIVRKKPIFKKATVTLEDHLACKCETVAAARP 188
>gi|15208656 platelet-derived growth factor alpha isoform 2
preproprotein [Homo sapiens]
Length = 196
Score = 45.8 bits (107), Expect = 6e-05
Identities = 25/76 (32%), Positives = 37/76 (48%), Gaps = 3/76 (3%)
Query: 127 STNTFFKPPCVNVFRCGGCCNEESLICMNTSTSYISKQLFEISVPLTSVPEL--VPVKVA 184
S N PPCV V RC GCCN S+ C + + S ++ ++ + P+L V V++
Sbjct: 114 SANFLIWPPCVEVKRCTGCCNTSSVKCQPSRVHHRSVKVAKVEY-VRKKPKLKEVQVRLE 172
Query: 185 NHTGCKCLPTAPRHPY 200
H C C T+ Y
Sbjct: 173 EHLECACATTSLNPDY 188
>gi|77695917 platelet-derived growth factor alpha isoform 1
preproprotein [Homo sapiens]
Length = 211
Score = 45.8 bits (107), Expect = 6e-05
Identities = 25/76 (32%), Positives = 37/76 (48%), Gaps = 3/76 (3%)
Query: 127 STNTFFKPPCVNVFRCGGCCNEESLICMNTSTSYISKQLFEISVPLTSVPEL--VPVKVA 184
S N PPCV V RC GCCN S+ C + + S ++ ++ + P+L V V++
Sbjct: 114 SANFLIWPPCVEVKRCTGCCNTSSVKCQPSRVHHRSVKVAKVEY-VRKKPKLKEVQVRLE 172
Query: 185 NHTGCKCLPTAPRHPY 200
H C C T+ Y
Sbjct: 173 EHLECACATTSLNPDY 188
>gi|13376808 platelet derived growth factor D isoform 1 precursor
[Homo sapiens]
Length = 370
Score = 41.6 bits (96), Expect = 0.001
Identities = 39/163 (23%), Positives = 69/163 (42%), Gaps = 21/163 (12%)
Query: 41 EQQIRAASSLEELLRITHSEDWKLWRCRLRLKSFTSMDSRSASHRSTRFAATFYDIETLK 100
+++I ++E+LL+ + E W+ + L D+ RS + D++ L
Sbjct: 211 DKKIAEFDTVEDLLKYFNPESWQEDLENMYL------DTPRYRGRSYHDRKSKVDLDRL- 263
Query: 101 VIDEEWQRTQCSPRETCVEVASELGKSTNTFFKPPCVNVFRCGGCC-----NEESLICMN 155
+++ +R C+PR V + EL K N F P C+ V RCGG C N S C +
Sbjct: 264 --NDDAKRYSCTPRNYSVNIREEL-KLANVVFFPRCLLVQRCGGNCGCGTVNWRSCTCNS 320
Query: 156 TSTSYISKQLFEISV------PLTSVPELVPVKVANHTGCKCL 192
T ++ + LV +++ +H C C+
Sbjct: 321 GKTVKKYHEVLQFEPGHIKRRGRAKTMALVDIQLDHHERCDCI 363
>gi|15451921 platelet derived growth factor D isoform 2 precursor
[Homo sapiens]
Length = 364
Score = 41.6 bits (96), Expect = 0.001
Identities = 39/163 (23%), Positives = 69/163 (42%), Gaps = 21/163 (12%)
Query: 41 EQQIRAASSLEELLRITHSEDWKLWRCRLRLKSFTSMDSRSASHRSTRFAATFYDIETLK 100
+++I ++E+LL+ + E W+ + L D+ RS + D++ L
Sbjct: 205 DKKIAEFDTVEDLLKYFNPESWQEDLENMYL------DTPRYRGRSYHDRKSKVDLDRL- 257
Query: 101 VIDEEWQRTQCSPRETCVEVASELGKSTNTFFKPPCVNVFRCGGCC-----NEESLICMN 155
+++ +R C+PR V + EL K N F P C+ V RCGG C N S C +
Sbjct: 258 --NDDAKRYSCTPRNYSVNIREEL-KLANVVFFPRCLLVQRCGGNCGCGTVNWRSCTCNS 314
Query: 156 TSTSYISKQLFEISV------PLTSVPELVPVKVANHTGCKCL 192
T ++ + LV +++ +H C C+
Sbjct: 315 GKTVKKYHEVLQFEPGHIKRRGRAKTMALVDIQLDHHERCDCI 357
>gi|54292117 ADAM metallopeptidase domain 28 isoform 3 preproprotein
[Homo sapiens]
Length = 540
Score = 34.3 bits (77), Expect = 0.17
Identities = 22/87 (25%), Positives = 35/87 (40%), Gaps = 23/87 (26%)
Query: 264 FDEDRCECVCKTPCPKDLIQHP----------KNCSCFECKESLETCCQKHKLFHPDTCS 313
F++ C+ P P D+I P ++C C +E CC D +
Sbjct: 387 FEDKLSNCLFNAPLPTDIISTPICGNQLVEMGEDCDCGTSEECTNICC--------DAKT 438
Query: 314 CEDRCPFHTRPCASGKTACAKHCRFPK 340
C+ + F CA G+ C + C+F K
Sbjct: 439 CKIKATFQ---CALGE--CCEKCQFKK 460
>gi|98985828 ADAM metallopeptidase domain 28 isoform 1 preproprotein
[Homo sapiens]
Length = 775
Score = 34.3 bits (77), Expect = 0.17
Identities = 22/87 (25%), Positives = 35/87 (40%), Gaps = 23/87 (26%)
Query: 264 FDEDRCECVCKTPCPKDLIQHP----------KNCSCFECKESLETCCQKHKLFHPDTCS 313
F++ C+ P P D+I P ++C C +E CC D +
Sbjct: 387 FEDKLSNCLFNAPLPTDIISTPICGNQLVEMGEDCDCGTSEECTNICC--------DAKT 438
Query: 314 CEDRCPFHTRPCASGKTACAKHCRFPK 340
C+ + F CA G+ C + C+F K
Sbjct: 439 CKIKATFQ---CALGE--CCEKCQFKK 460
>gi|89363020 nuclear transcription factor, X-box binding-like 1
[Homo sapiens]
Length = 911
Score = 34.3 bits (77), Expect = 0.17
Identities = 26/98 (26%), Positives = 35/98 (35%), Gaps = 16/98 (16%)
Query: 257 LCGPHMMFDEDRCECVCKT----PCPKDLIQHPKNCSC------FECKESLETCCQK-HK 305
+CG + CE VC CP+ + C C C E + TC K
Sbjct: 364 VCGKTLPCGNHTCEQVCHVGACGECPRS---GKRFCPCQKSKFSLPCTEDVPTCGDSCDK 420
Query: 306 LFHPDTCSCEDRCPFHTRPCASGKTACAKHCRFPKEKR 343
+ C RC H PC + + KHCR K +
Sbjct: 421 VLECGIHRCSQRC--HRGPCETCRQEVEKHCRCGKHTK 456
>gi|122937257 thrombospondin, type I, domain containing 7B [Homo
sapiens]
Length = 1577
Score = 33.9 bits (76), Expect = 0.23
Identities = 28/86 (32%), Positives = 40/86 (46%), Gaps = 11/86 (12%)
Query: 254 EPALCGPHMMFDEDRCECVCKTPCPKD--LIQHPKNCSC-FECKE--SLETCCQ--KHKL 306
E ALCG M F + + +C PCP D L + + +C C + S ET + + +
Sbjct: 1316 EDALCG-EMPFQDSILKQLCSVPCPGDCHLTEWSEWSTCELTCIDGRSFETVGRQSRSRT 1374
Query: 307 FHPDTCSCEDRCP---FHTRPCASGK 329
F + +D CP TRPC GK
Sbjct: 1375 FIIQSFENQDSCPQQVLETRPCTGGK 1400
>gi|33598931 scavenger receptor class F, member 1 isoform 3
precursor [Homo sapiens]
Length = 569
Score = 33.5 bits (75), Expect = 0.30
Identities = 23/82 (28%), Positives = 31/82 (37%), Gaps = 7/82 (8%)
Query: 255 PALCGPHMMFDEDRCECVCKTPCPKDLIQHPKNC--SCFECKESLETCCQKHKLFHPDTC 312
P CGPH D C C+ + P C + C+++ C K +
Sbjct: 132 PCACGPHGRCDPATGVCHCEPGWWSSTCRRPCQCNTAAARCEQATGACVCKPGWWGR--- 188
Query: 313 SCEDRCPFHTRPCA--SGKTAC 332
C RC H PC SG+ AC
Sbjct: 189 RCSFRCNCHGSPCEQDSGRCAC 210
>gi|33598929 scavenger receptor class F, member 1 isoform 1
precursor [Homo sapiens]
Length = 830
Score = 33.5 bits (75), Expect = 0.30
Identities = 23/82 (28%), Positives = 31/82 (37%), Gaps = 7/82 (8%)
Query: 255 PALCGPHMMFDEDRCECVCKTPCPKDLIQHPKNC--SCFECKESLETCCQKHKLFHPDTC 312
P CGPH D C C+ + P C + C+++ C K +
Sbjct: 132 PCACGPHGRCDPATGVCHCEPGWWSSTCRRPCQCNTAAARCEQATGACVCKPGWWGR--- 188
Query: 313 SCEDRCPFHTRPCA--SGKTAC 332
C RC H PC SG+ AC
Sbjct: 189 RCSFRCNCHGSPCEQDSGRCAC 210
>gi|145309306 scavenger receptor class F, member 1 isoform 5
precursor [Homo sapiens]
Length = 744
Score = 33.5 bits (75), Expect = 0.30
Identities = 23/82 (28%), Positives = 31/82 (37%), Gaps = 7/82 (8%)
Query: 255 PALCGPHMMFDEDRCECVCKTPCPKDLIQHPKNC--SCFECKESLETCCQKHKLFHPDTC 312
P CGPH D C C+ + P C + C+++ C K +
Sbjct: 132 PCACGPHGRCDPATGVCHCEPGWWSSTCRRPCQCNTAAARCEQATGACVCKPGWWGR--- 188
Query: 313 SCEDRCPFHTRPCA--SGKTAC 332
C RC H PC SG+ AC
Sbjct: 189 RCSFRCNCHGSPCEQDSGRCAC 210
>gi|22212927 nuclear transcription factor, X-box binding 1 isoform 3
[Homo sapiens]
Length = 833
Score = 33.5 bits (75), Expect = 0.30
Identities = 56/262 (21%), Positives = 90/262 (34%), Gaps = 53/262 (20%)
Query: 107 QRTQCSP-RETCVEVASELGKSTNTFFKPPCVNVFRCGGCCNEESLICMNTSTSYISKQL 165
Q +C P +T + ELG S+ P V CG C + L C + + ++L
Sbjct: 589 QLVRCCPCGQTPLSQLLELGSSSRKTCMDP---VPSCGKVCGKP-LPCGSLDFIHTCEKL 644
Query: 166 FEISVPLTSVPELVPVKVANHTGCKCLPTAPRHPYSIIRRSIQIPEEDRCSHSKKLCPID 225
+ P + C+C P + ++ ED K C
Sbjct: 645 CHEG-------DCGPCSRTSVISCRCSFRTKELPCTSLK------SEDATFMCDKRCNKK 691
Query: 226 MLWDSNKCK--CVLQEENPLAGTEDHSHLQEPALCGPHMMFDEDRCECVCKTP------- 276
L +KC C + +E+ P +CG + RCE C
Sbjct: 692 RLCGRHKCNEICCVDKEHKC-----------PLICGRKLRCGLHRCEEPCHRGNCQTCWQ 740
Query: 277 ---------CPKDLIQHPKNCSCFECKESLETCCQKHKLFHP--DTCSCEDRCP---FHT 322
C +I P C E +TC + H+ HP +C E++CP F T
Sbjct: 741 ASFDELTCHCGASVIYPPVPCGT-RPPECTQTCARVHECDHPVYHSCHSEEKCPPCTFLT 799
Query: 323 RPCASGKTACAKHCRFPKEKRA 344
+ GK + + ++KR+
Sbjct: 800 QKWCMGKHEQSHYWASTQKKRS 821
>gi|20336246 proprotein convertase subtilisin/kexin type 5
preproprotein [Homo sapiens]
Length = 913
Score = 33.5 bits (75), Expect = 0.30
Identities = 26/94 (27%), Positives = 35/94 (37%), Gaps = 12/94 (12%)
Query: 250 SHLQEPALCGPHMMFDEDRCECVCKTPCPKDLIQHPKNCSCFECKESLETCCQKHKL--- 306
SH + C +E+ CV T CP Q K C +C E+ +TC + H
Sbjct: 699 SHGDQCMSCKYGYFLNEETNSCV--THCPDGSYQDTKKNLCRKCSENCKTCTEFHNCTEC 756
Query: 307 -----FHPDTC--SCEDRCPFHTRPCASGKTACA 333
C SCED F+ + C CA
Sbjct: 757 RDGLSLQGSRCSVSCEDGRYFNGQDCQPCHRFCA 790
>gi|58082087 late cornified envelope-like proline-rich 1 [Homo
sapiens]
Length = 98
Score = 32.7 bits (73), Expect = 0.51
Identities = 21/81 (25%), Positives = 25/81 (30%), Gaps = 13/81 (16%)
Query: 254 EPALCGPHMMFDEDRCECVCKTPCPKDLIQH----------PKNCSCFECKESLETCCQK 303
EP C P E +CE C+ C K L+Q P C C + C
Sbjct: 15 EPKNCDPKC---EQKCESKCQPSCLKKLLQRCFEKCPWEKCPAPPKCLPCPSQSPSSCPP 71
Query: 304 HKLFHPDTCSCEDRCPFHTRP 324
P C CP P
Sbjct: 72 QPCTKPCPPKCPSSCPHACPP 92
>gi|22212925 nuclear transcription factor, X-box binding 1 isoform 2
[Homo sapiens]
Length = 1024
Score = 32.3 bits (72), Expect = 0.66
Identities = 54/247 (21%), Positives = 83/247 (33%), Gaps = 53/247 (21%)
Query: 107 QRTQCSP-RETCVEVASELGKSTNTFFKPPCVNVFRCGGCCNEESLICMNTSTSYISKQL 165
Q +C P +T + ELG S+ P V CG C + L C + + ++L
Sbjct: 589 QLVRCCPCGQTPLSQLLELGSSSRKTCMDP---VPSCGKVCGKP-LPCGSLDFIHTCEKL 644
Query: 166 FEISVPLTSVPELVPVKVANHTGCKCLPTAPRHPYSIIRRSIQIPEEDRCSHSKKLCPID 225
+ P + C+C P + ++ ED K C
Sbjct: 645 CHEG-------DCGPCSRTSVISCRCSFRTKELPCTSLK------SEDATFMCDKRCNKK 691
Query: 226 MLWDSNKCK--CVLQEENPLAGTEDHSHLQEPALCGPHMMFDEDRCECVCKTP------- 276
L +KC C + +E+ P +CG + RCE C
Sbjct: 692 RLCGRHKCNEICCVDKEHKC-----------PLICGRKLRCGLHRCEEPCHRGNCQTCWQ 740
Query: 277 ---------CPKDLIQHPKNCSCFECKESLETCCQKHKLFHP--DTCSCEDRCP---FHT 322
C +I P C E +TC + H+ HP +C E++CP F T
Sbjct: 741 ASFDELTCHCGASVIYPPVPCGT-RPPECTQTCARVHECDHPVYHSCHSEEKCPPCTFLT 799
Query: 323 RPCASGK 329
+ GK
Sbjct: 800 QKWCMGK 806
>gi|21361137 nuclear transcription factor, X-box binding 1 isoform 1
[Homo sapiens]
Length = 1120
Score = 32.3 bits (72), Expect = 0.66
Identities = 54/247 (21%), Positives = 83/247 (33%), Gaps = 53/247 (21%)
Query: 107 QRTQCSP-RETCVEVASELGKSTNTFFKPPCVNVFRCGGCCNEESLICMNTSTSYISKQL 165
Q +C P +T + ELG S+ P V CG C + L C + + ++L
Sbjct: 589 QLVRCCPCGQTPLSQLLELGSSSRKTCMDP---VPSCGKVCGKP-LPCGSLDFIHTCEKL 644
Query: 166 FEISVPLTSVPELVPVKVANHTGCKCLPTAPRHPYSIIRRSIQIPEEDRCSHSKKLCPID 225
+ P + C+C P + ++ ED K C
Sbjct: 645 CHEG-------DCGPCSRTSVISCRCSFRTKELPCTSLK------SEDATFMCDKRCNKK 691
Query: 226 MLWDSNKCK--CVLQEENPLAGTEDHSHLQEPALCGPHMMFDEDRCECVCKTP------- 276
L +KC C + +E+ P +CG + RCE C
Sbjct: 692 RLCGRHKCNEICCVDKEHKC-----------PLICGRKLRCGLHRCEEPCHRGNCQTCWQ 740
Query: 277 ---------CPKDLIQHPKNCSCFECKESLETCCQKHKLFHP--DTCSCEDRCP---FHT 322
C +I P C E +TC + H+ HP +C E++CP F T
Sbjct: 741 ASFDELTCHCGASVIYPPVPCGT-RPPECTQTCARVHECDHPVYHSCHSEEKCPPCTFLT 799
Query: 323 RPCASGK 329
+ GK
Sbjct: 800 QKWCMGK 806
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.132 0.436
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,939,256
Number of Sequences: 37866
Number of extensions: 797815
Number of successful extensions: 2090
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 20
Number of HSP's successfully gapped in prelim test: 77
Number of HSP's that attempted gapping in prelim test: 2003
Number of HSP's gapped (non-prelim): 158
length of query: 354
length of database: 18,247,518
effective HSP length: 103
effective length of query: 251
effective length of database: 14,347,320
effective search space: 3601177320
effective search space used: 3601177320
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.