Guide to the Human Genome
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Name: PDGFB Sequence: fasta or formatted (241aa) NCBI GI: 4505681
Description:

platelet-derived growth factor beta isoform 1 preproprotein

Referenced in:

Retroviral Oncogene Homologs
Platelets and Megakaryocytes

Other entries for this name:
alt prot [226aa] platelet-derived growth factor beta isoform 2 preproprotein
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             6.6         16           3
 C cysteine            4.6         11           2
 D aspartate           4.1         10           2
 E glutamate           7.9         19           2
 F phenylalanine       2.5          6           1
 G glycine             5.4         13           2
 H histidine           2.9          7           1
 I isoleucine          4.1         10           1
 K lysine              5.8         14           2
 L leucine             9.5         23           2
 M methionine          1.7          4           1
 N asparagine          2.9          7           2
 P proline             5.8         14           2
 Q glutamine           3.7          9           1
 R arginine           11.2         27           2
 S serine              5.8         14           1
 T threonine           7.1         17           1
 V valine              6.6         16           1
 W tryptophan          0.8          2           1
 Y tyrosine            0.8          2           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   platelet-derived growth factor beta isoform 1 preprop... 
PDGFB                 0.904   platelet-derived growth factor beta isoform 2 prepro...
PDGFA                 0.260   platelet-derived growth factor alpha isoform 2 prepr...
PDGFA                 0.260   platelet-derived growth factor alpha isoform 1 prepr...
VEGFB                 0.058   vascular endothelial growth factor B 
FIGF                  0.055   vascular endothelial growth factor D preproprotein [H...
VEGFC                 0.055   vascular endothelial growth factor C preproprotein [H...
PGF                   0.045   placental growth factor, vascular endothelial growth...
VEGFA                 0.038   vascular endothelial growth factor A isoform c precu...
VEGFA                 0.038   vascular endothelial growth factor A isoform b precu...
VEGFA                 0.038   vascular endothelial growth factor A isoform a precu...
VEGFA                 0.036   vascular endothelial growth factor A isoform e precu...
VEGFA                 0.036   vascular endothelial growth factor A isoform d precu...
VEGFA                 0.036   vascular endothelial growth factor A isoform g precu...
VEGFA                 0.036   vascular endothelial growth factor A isoform f precu...
PDGFC                 0.030   platelet-derived growth factor C precursor 
PDGFD                 0.011   platelet derived growth factor D isoform 1 precursor...
PDGFD                 0.011   platelet derived growth factor D isoform 2 precursor...
L1CAM                 0.009   L1 cell adhesion molecule isoform 3 precursor [Homo...
L1CAM                 0.009   L1 cell adhesion molecule isoform 2 precursor 
WIBG                  0.009   within bgcn homolog isoform 2 
WIBG                  0.009   within bgcn homolog isoform 1 
MRPL46                0.009   mitochondrial ribosomal protein L46 
CLASP1                0.006   CLIP-associating protein 1 isoform 3 
CLASP1                0.006   CLIP-associating protein 1 isoform 2 
CLASP1                0.006   CLIP-associating protein 1 isoform 1 
EPPK1                 0.006   epiplakin 1 
NPHP1                 0.006   nephrocystin 1 isoform 4 
NPHP1                 0.006   nephrocystin 1 isoform 3 
NPHP1                 0.006   nephrocystin 1 isoform 2 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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