Guide to the Human Genome
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Name: PDGFA Sequence: fasta or formatted (211aa) NCBI GI: 77695917
Description:

platelet-derived growth factor alpha isoform 1 preproprotein

Referenced in:

Platelets and Megakaryocytes

Other entries for this name:
alt prot [196aa] platelet-derived growth factor alpha isoform 2 preproprotein
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             6.2         13           1
 C cysteine            4.7         10           2
 D aspartate           3.3          7           1
 E glutamate           9.5         20           2
 F phenylalanine       0.5          1           1
 G glycine             3.3          7           1
 H histidine           3.8          8           2
 I isoleucine          4.7         10           1
 K lysine              8.1         17           2
 L leucine             9.5         20           4
 M methionine          0.5          1           1
 N asparagine          1.4          3           1
 P proline             6.6         14           2
 Q glutamine           2.4          5           1
 R arginine           11.4         24           2
 S serine              7.1         15           2
 T threonine           5.7         12           2
 V valine              9.0         19           1
 W tryptophan          0.5          1           1
 Y tyrosine            1.9          4           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   platelet-derived growth factor alpha isoform 1 prepr... 
PDGFA                 0.908   platelet-derived growth factor alpha isoform 2 prepr...
PDGFB                 0.302   platelet-derived growth factor beta isoform 1 preprop...
PDGFB                 0.282   platelet-derived growth factor beta isoform 2 prepro...
PGF                   0.069   placental growth factor, vascular endothelial growth...
VEGFB                 0.064   vascular endothelial growth factor B 
VEGFA                 0.062   vascular endothelial growth factor A isoform c precu...
VEGFA                 0.054   vascular endothelial growth factor A isoform b precu...
VEGFA                 0.054   vascular endothelial growth factor A isoform a precu...
FIGF                  0.052   vascular endothelial growth factor D preproprotein [H...
VEGFC                 0.045   vascular endothelial growth factor C preproprotein [H...
PDGFC                 0.037   platelet-derived growth factor C precursor 
VEGFA                 0.037   vascular endothelial growth factor A isoform f precu...
VEGFA                 0.035   vascular endothelial growth factor A isoform e precu...
VEGFA                 0.035   vascular endothelial growth factor A isoform d precu...
VEGFA                 0.035   vascular endothelial growth factor A isoform g precu...
PDGFD                 0.027   platelet derived growth factor D isoform 1 precursor...
PDGFD                 0.027   platelet derived growth factor D isoform 2 precursor...
CXCL12                0.017   chemokine (C-X-C motif) ligand 12 (stromal cell-deri...
APC2                  0.015   adenomatosis polyposis coli 2 
C1orf68               0.012   skin-specific protein 32 
TBCKL                 0.010   TBC domain-containing protein kinase-like 
LOC100294088          0.007   PREDICTED: hypothetical protein, partial 
SPANXN3               0.007   SPANX-N3 protein 
NF2                   0.007   neurofibromin 2 isoform 7 
NF2                   0.007   neurofibromin 2 isoform 2 
NF2                   0.007   neurofibromin 2 isoform 2 
NF2                   0.007   neurofibromin 2 isoform 7 
NF2                   0.007   neurofibromin 2 isoform 6 
NF2                   0.007   neurofibromin 2 isoform 5 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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