Search of human proteins with 4758012

Search of human proteins with 4758012

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4758012 clathrin heavy chain 1 [Homo sapiens]
         (1675 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4758012 clathrin heavy chain 1 [Homo sapiens]                     3354   0.0  
gi|242246985 clathrin, heavy polypeptide-like 1 isoform 1 [Homo ...  2840   0.0  
gi|242247001 clathrin, heavy polypeptide-like 1 isoform 2 [Homo ...  2610   0.0  
gi|208022639 hypothetical protein LOC130162 isoform 2 [Homo sapi...    69   5e-11
gi|208022637 hypothetical protein LOC130162 isoform 1 [Homo sapi...    69   5e-11
gi|56243599 WD repeat domain 35 isoform 2 [Homo sapiens]               36   0.27 
gi|55743161 WD repeat domain 35 isoform 1 [Homo sapiens]               36   0.27 
gi|7706127 core 2 beta-1,6-N-acetylglucosaminyltransferase 3 [Ho...    35   0.47 
gi|114199473 vacuolar protein sorting 41 isoform 2 [Homo sapiens]      33   2.3  
gi|114199475 vacuolar protein sorting 41 isoform 1 [Homo sapiens]      33   2.3  
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ...    32   4.0  
gi|194294521 intersectin 2 isoform 1 [Homo sapiens]                    32   4.0  
gi|194294525 intersectin 2 isoform 2 [Homo sapiens]                    32   4.0  
gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo s...    32   5.2  
gi|21361320 TRK-fused [Homo sapiens]                                   32   6.8  
gi|56090139 TRK-fused [Homo sapiens]                                   32   6.8  
gi|72534736 zinc finger protein 613 isoform 1 [Homo sapiens]           32   6.8  
gi|21362003 zinc finger protein 613 isoform 2 [Homo sapiens]           32   6.8  
gi|154277118 spectrin repeat containing, nuclear envelope 1 isof...    31   8.8  
gi|23097308 spectrin repeat containing, nuclear envelope 1 isofo...    31   8.8  
gi|154277116 spectrin repeat containing, nuclear envelope 1 isof...    31   8.8  
gi|55770846 catenin, alpha 2 [Homo sapiens]                            31   8.8  
gi|148727333 adenylate kinase 7 [Homo sapiens]                         31   8.8  
gi|134142824 forkhead box D2 [Homo sapiens]                            31   8.8  

>gi|4758012 clathrin heavy chain 1 [Homo sapiens]
          Length = 1675

 Score = 3354 bits (8697), Expect = 0.0
 Identities = 1675/1675 (100%), Positives = 1675/1675 (100%)

Query: 1    MAQILPIRFQEHLQLQNLGINPANIGFSTLTMESDKFICIREKVGEQAQVVIIDMNDPSN 60
            MAQILPIRFQEHLQLQNLGINPANIGFSTLTMESDKFICIREKVGEQAQVVIIDMNDPSN
Sbjct: 1    MAQILPIRFQEHLQLQNLGINPANIGFSTLTMESDKFICIREKVGEQAQVVIIDMNDPSN 60

Query: 61   PIRRPISADSAIMNPASKVIALKAGKTLQIFNIEMKSKMKAHTMTDDVTFWKWISLNTVA 120
            PIRRPISADSAIMNPASKVIALKAGKTLQIFNIEMKSKMKAHTMTDDVTFWKWISLNTVA
Sbjct: 61   PIRRPISADSAIMNPASKVIALKAGKTLQIFNIEMKSKMKAHTMTDDVTFWKWISLNTVA 120

Query: 121  LVTDNAVYHWSMEGESQPVKMFDRHSSLAGCQIINYRTDAKQKWLLLTGISAQQNRVVGA 180
            LVTDNAVYHWSMEGESQPVKMFDRHSSLAGCQIINYRTDAKQKWLLLTGISAQQNRVVGA
Sbjct: 121  LVTDNAVYHWSMEGESQPVKMFDRHSSLAGCQIINYRTDAKQKWLLLTGISAQQNRVVGA 180

Query: 181  MQLYSVDRKVSQPIEGHAASFAQFKMEGNAEESTLFCFAVRGQAGGKLHIIEVGTPPTGN 240
            MQLYSVDRKVSQPIEGHAASFAQFKMEGNAEESTLFCFAVRGQAGGKLHIIEVGTPPTGN
Sbjct: 181  MQLYSVDRKVSQPIEGHAASFAQFKMEGNAEESTLFCFAVRGQAGGKLHIIEVGTPPTGN 240

Query: 241  QPFPKKAVDVFFPPEAQNDFPVAMQISEKHDVVFLITKYGYIHLYDLETGTCIYMNRISG 300
            QPFPKKAVDVFFPPEAQNDFPVAMQISEKHDVVFLITKYGYIHLYDLETGTCIYMNRISG
Sbjct: 241  QPFPKKAVDVFFPPEAQNDFPVAMQISEKHDVVFLITKYGYIHLYDLETGTCIYMNRISG 300

Query: 301  ETIFVTAPHEATAGIIGVNRKGQVLSVCVEEENIIPYITNVLQNPDLALRMAVRNNLAGA 360
            ETIFVTAPHEATAGIIGVNRKGQVLSVCVEEENIIPYITNVLQNPDLALRMAVRNNLAGA
Sbjct: 301  ETIFVTAPHEATAGIIGVNRKGQVLSVCVEEENIIPYITNVLQNPDLALRMAVRNNLAGA 360

Query: 361  EELFARKFNALFAQGNYSEAAKVAANAPKGILRTPDTIRRFQSVPAQPGQTSPLLQYFGI 420
            EELFARKFNALFAQGNYSEAAKVAANAPKGILRTPDTIRRFQSVPAQPGQTSPLLQYFGI
Sbjct: 361  EELFARKFNALFAQGNYSEAAKVAANAPKGILRTPDTIRRFQSVPAQPGQTSPLLQYFGI 420

Query: 421  LLDQGQLNKYESLELCRPVLQQGRKQLLEKWLKEDKLECSEELGDLVKSVDPTLALSVYL 480
            LLDQGQLNKYESLELCRPVLQQGRKQLLEKWLKEDKLECSEELGDLVKSVDPTLALSVYL
Sbjct: 421  LLDQGQLNKYESLELCRPVLQQGRKQLLEKWLKEDKLECSEELGDLVKSVDPTLALSVYL 480

Query: 481  RANVPNKVIQCFAETGQVQKIVLYAKKVGYTPDWIFLLRNVMRISPDQGQQFAQMLVQDE 540
            RANVPNKVIQCFAETGQVQKIVLYAKKVGYTPDWIFLLRNVMRISPDQGQQFAQMLVQDE
Sbjct: 481  RANVPNKVIQCFAETGQVQKIVLYAKKVGYTPDWIFLLRNVMRISPDQGQQFAQMLVQDE 540

Query: 541  EPLADITQIVDVFMEYNLIQQCTAFLLDALKNNRPSEGPLQTRLLEMNLMHAPQVADAIL 600
            EPLADITQIVDVFMEYNLIQQCTAFLLDALKNNRPSEGPLQTRLLEMNLMHAPQVADAIL
Sbjct: 541  EPLADITQIVDVFMEYNLIQQCTAFLLDALKNNRPSEGPLQTRLLEMNLMHAPQVADAIL 600

Query: 601  GNQMFTHYDRAHIAQLCEKAGLLQRALEHFTDLYDIKRAVVHTHLLNPEWLVNYFGSLSV 660
            GNQMFTHYDRAHIAQLCEKAGLLQRALEHFTDLYDIKRAVVHTHLLNPEWLVNYFGSLSV
Sbjct: 601  GNQMFTHYDRAHIAQLCEKAGLLQRALEHFTDLYDIKRAVVHTHLLNPEWLVNYFGSLSV 660

Query: 661  EDSLECLRAMLSANIRQNLQICVQVASKYHEQLSTQSLIELFESFKSFEGLFYFLGSIVN 720
            EDSLECLRAMLSANIRQNLQICVQVASKYHEQLSTQSLIELFESFKSFEGLFYFLGSIVN
Sbjct: 661  EDSLECLRAMLSANIRQNLQICVQVASKYHEQLSTQSLIELFESFKSFEGLFYFLGSIVN 720

Query: 721  FSQDPDVHFKYIQAACKTGQIKEVERICRESNCYDPERVKNFLKEAKLTDQLPLIIVCDR 780
            FSQDPDVHFKYIQAACKTGQIKEVERICRESNCYDPERVKNFLKEAKLTDQLPLIIVCDR
Sbjct: 721  FSQDPDVHFKYIQAACKTGQIKEVERICRESNCYDPERVKNFLKEAKLTDQLPLIIVCDR 780

Query: 781  FDFVHDLVLYLYRNNLQKYIEIYVQKVNPSRLPVVIGGLLDVDCSEDVIKNLILVVRGQF 840
            FDFVHDLVLYLYRNNLQKYIEIYVQKVNPSRLPVVIGGLLDVDCSEDVIKNLILVVRGQF
Sbjct: 781  FDFVHDLVLYLYRNNLQKYIEIYVQKVNPSRLPVVIGGLLDVDCSEDVIKNLILVVRGQF 840

Query: 841  STDELVAEVEKRNRLKLLLPWLEARIHEGCEEPATHNALAKIYIDSNNNPERFLRENPYY 900
            STDELVAEVEKRNRLKLLLPWLEARIHEGCEEPATHNALAKIYIDSNNNPERFLRENPYY
Sbjct: 841  STDELVAEVEKRNRLKLLLPWLEARIHEGCEEPATHNALAKIYIDSNNNPERFLRENPYY 900

Query: 901  DSRVVGKYCEKRDPHLACVAYERGQCDLELINVCNENSLFKSLSRYLVRRKDPELWGSVL 960
            DSRVVGKYCEKRDPHLACVAYERGQCDLELINVCNENSLFKSLSRYLVRRKDPELWGSVL
Sbjct: 901  DSRVVGKYCEKRDPHLACVAYERGQCDLELINVCNENSLFKSLSRYLVRRKDPELWGSVL 960

Query: 961  LESNPYRRPLIDQVVQTALSETQDPEEVSVTVKAFMTADLPNELIELLEKIVLDNSVFSE 1020
            LESNPYRRPLIDQVVQTALSETQDPEEVSVTVKAFMTADLPNELIELLEKIVLDNSVFSE
Sbjct: 961  LESNPYRRPLIDQVVQTALSETQDPEEVSVTVKAFMTADLPNELIELLEKIVLDNSVFSE 1020

Query: 1021 HRNLQNLLILTAIKADRTRVMEYINRLDNYDAPDIANIAISNELFEEAFAIFRKFDVNTS 1080
            HRNLQNLLILTAIKADRTRVMEYINRLDNYDAPDIANIAISNELFEEAFAIFRKFDVNTS
Sbjct: 1021 HRNLQNLLILTAIKADRTRVMEYINRLDNYDAPDIANIAISNELFEEAFAIFRKFDVNTS 1080

Query: 1081 AVQVLIEHIGNLDRAYEFAERCNEPAVWSQLAKAQLQKGMVKEAIDSYIKADDPSSYMEV 1140
            AVQVLIEHIGNLDRAYEFAERCNEPAVWSQLAKAQLQKGMVKEAIDSYIKADDPSSYMEV
Sbjct: 1081 AVQVLIEHIGNLDRAYEFAERCNEPAVWSQLAKAQLQKGMVKEAIDSYIKADDPSSYMEV 1140

Query: 1141 VQAANTSGNWEELVKYLQMARKKARESYVETELIFALAKTNRLAELEEFINGPNNAHIQQ 1200
            VQAANTSGNWEELVKYLQMARKKARESYVETELIFALAKTNRLAELEEFINGPNNAHIQQ
Sbjct: 1141 VQAANTSGNWEELVKYLQMARKKARESYVETELIFALAKTNRLAELEEFINGPNNAHIQQ 1200

Query: 1201 VGDRCYDEKMYDAAKLLYNNVSNFGRLASTLVHLGEYQAAVDGARKANSTRTWKEVCFAC 1260
            VGDRCYDEKMYDAAKLLYNNVSNFGRLASTLVHLGEYQAAVDGARKANSTRTWKEVCFAC
Sbjct: 1201 VGDRCYDEKMYDAAKLLYNNVSNFGRLASTLVHLGEYQAAVDGARKANSTRTWKEVCFAC 1260

Query: 1261 VDGKEFRLAQMCGLHIVVHADELEELINYYQDRGYFEELITMLEAALGLERAHMGMFTEL 1320
            VDGKEFRLAQMCGLHIVVHADELEELINYYQDRGYFEELITMLEAALGLERAHMGMFTEL
Sbjct: 1261 VDGKEFRLAQMCGLHIVVHADELEELINYYQDRGYFEELITMLEAALGLERAHMGMFTEL 1320

Query: 1321 AILYSKFKPQKMREHLELFWSRVNIPKVLRAAEQAHLWAELVFLYDKYEEYDNAIITMMN 1380
            AILYSKFKPQKMREHLELFWSRVNIPKVLRAAEQAHLWAELVFLYDKYEEYDNAIITMMN
Sbjct: 1321 AILYSKFKPQKMREHLELFWSRVNIPKVLRAAEQAHLWAELVFLYDKYEEYDNAIITMMN 1380

Query: 1381 HPTDAWKEGQFKDIITKVANVELYYRAIQFYLEFKPLLLNDLLMVLSPRLDHTRAVNYFS 1440
            HPTDAWKEGQFKDIITKVANVELYYRAIQFYLEFKPLLLNDLLMVLSPRLDHTRAVNYFS
Sbjct: 1381 HPTDAWKEGQFKDIITKVANVELYYRAIQFYLEFKPLLLNDLLMVLSPRLDHTRAVNYFS 1440

Query: 1441 KVKQLPLVKPYLRSVQNHNNKSVNESLNNLFITEEDYQALRTSIDAYDNFDNISLAQRLE 1500
            KVKQLPLVKPYLRSVQNHNNKSVNESLNNLFITEEDYQALRTSIDAYDNFDNISLAQRLE
Sbjct: 1441 KVKQLPLVKPYLRSVQNHNNKSVNESLNNLFITEEDYQALRTSIDAYDNFDNISLAQRLE 1500

Query: 1501 KHELIEFRRIAAYLFKGNNRWKQSVELCKKDSLYKDAMQYASESKDTELAEELLQWFLQE 1560
            KHELIEFRRIAAYLFKGNNRWKQSVELCKKDSLYKDAMQYASESKDTELAEELLQWFLQE
Sbjct: 1501 KHELIEFRRIAAYLFKGNNRWKQSVELCKKDSLYKDAMQYASESKDTELAEELLQWFLQE 1560

Query: 1561 EKRECFGACLFTCYDLLRPDVVLETAWRHNIMDFAMPYFIQVMKEYLTKVDKLDASESLR 1620
            EKRECFGACLFTCYDLLRPDVVLETAWRHNIMDFAMPYFIQVMKEYLTKVDKLDASESLR
Sbjct: 1561 EKRECFGACLFTCYDLLRPDVVLETAWRHNIMDFAMPYFIQVMKEYLTKVDKLDASESLR 1620

Query: 1621 KEEEQATETQPIVYGQPQLMLTAGPSVAVPPQAPFGYGYTAPPYGQPQPGFGYSM 1675
            KEEEQATETQPIVYGQPQLMLTAGPSVAVPPQAPFGYGYTAPPYGQPQPGFGYSM
Sbjct: 1621 KEEEQATETQPIVYGQPQLMLTAGPSVAVPPQAPFGYGYTAPPYGQPQPGFGYSM 1675


>gi|242246985 clathrin, heavy polypeptide-like 1 isoform 1 [Homo
            sapiens]
          Length = 1640

 Score = 2840 bits (7362), Expect = 0.0
 Identities = 1389/1634 (85%), Positives = 1529/1634 (93%)

Query: 1    MAQILPIRFQEHLQLQNLGINPANIGFSTLTMESDKFICIREKVGEQAQVVIIDMNDPSN 60
            MAQILP+RFQEH QLQNLGINPANIGFSTLTMESDKFICIREKVGEQAQV IIDM+DP  
Sbjct: 1    MAQILPVRFQEHFQLQNLGINPANIGFSTLTMESDKFICIREKVGEQAQVTIIDMSDPMA 60

Query: 61   PIRRPISADSAIMNPASKVIALKAGKTLQIFNIEMKSKMKAHTMTDDVTFWKWISLNTVA 120
            PIRRPISA+SAIMNPASKVIALKAGKTLQIFNIEMKSKMKAHTM ++V FWKW+S+NTVA
Sbjct: 61   PIRRPISAESAIMNPASKVIALKAGKTLQIFNIEMKSKMKAHTMAEEVIFWKWVSVNTVA 120

Query: 121  LVTDNAVYHWSMEGESQPVKMFDRHSSLAGCQIINYRTDAKQKWLLLTGISAQQNRVVGA 180
            LVT+ AVYHWSMEG+SQP+KMFDRH+SL GCQ+I+YRTD  QKWLLL GISAQQNRVVGA
Sbjct: 121  LVTETAVYHWSMEGDSQPMKMFDRHTSLVGCQVIHYRTDEYQKWLLLVGISAQQNRVVGA 180

Query: 181  MQLYSVDRKVSQPIEGHAASFAQFKMEGNAEESTLFCFAVRGQAGGKLHIIEVGTPPTGN 240
            MQLYSVDRKVSQPIEGHAA+FA+FKMEGNA+ +TLFCFAVR   GGKLHIIEVG P  GN
Sbjct: 181  MQLYSVDRKVSQPIEGHAAAFAEFKMEGNAKPATLFCFAVRNPTGGKLHIIEVGQPAAGN 240

Query: 241  QPFPKKAVDVFFPPEAQNDFPVAMQISEKHDVVFLITKYGYIHLYDLETGTCIYMNRISG 300
            QPF KKAVDVFFPPEAQNDFPVAMQI  KH V++LITKYGY+HLYDLE+G CI MNRIS 
Sbjct: 241  QPFVKKAVDVFFPPEAQNDFPVAMQIGAKHGVIYLITKYGYLHLYDLESGVCICMNRISA 300

Query: 301  ETIFVTAPHEATAGIIGVNRKGQVLSVCVEEENIIPYITNVLQNPDLALRMAVRNNLAGA 360
            +TIFVTAPH+ T+GIIGVN+KGQVLSVCVEE+NI+ Y TNVLQNPDL LR+AVR+NLAGA
Sbjct: 301  DTIFVTAPHKPTSGIIGVNKKGQVLSVCVEEDNIVNYATNVLQNPDLGLRLAVRSNLAGA 360

Query: 361  EELFARKFNALFAQGNYSEAAKVAANAPKGILRTPDTIRRFQSVPAQPGQTSPLLQYFGI 420
            E+LF RKFN LFAQG+Y+EAAKVAA+APKGILRT +T+++FQS+PAQ GQ SPLLQYFGI
Sbjct: 361  EKLFVRKFNTLFAQGSYAEAAKVAASAPKGILRTRETVQKFQSIPAQSGQASPLLQYFGI 420

Query: 421  LLDQGQLNKYESLELCRPVLQQGRKQLLEKWLKEDKLECSEELGDLVKSVDPTLALSVYL 480
            LLDQGQLNK ESLELC  VLQQGRKQLLEKWLKEDKLECSEELGDLVK+ DP LALSVYL
Sbjct: 421  LLDQGQLNKLESLELCHLVLQQGRKQLLEKWLKEDKLECSEELGDLVKTTDPMLALSVYL 480

Query: 481  RANVPNKVIQCFAETGQVQKIVLYAKKVGYTPDWIFLLRNVMRISPDQGQQFAQMLVQDE 540
            RANVP+KVIQCFAETGQ QKIVLYAKKVGYTPDWIFLLR VM+ISP+QG QF++MLVQDE
Sbjct: 481  RANVPSKVIQCFAETGQFQKIVLYAKKVGYTPDWIFLLRGVMKISPEQGLQFSRMLVQDE 540

Query: 541  EPLADITQIVDVFMEYNLIQQCTAFLLDALKNNRPSEGPLQTRLLEMNLMHAPQVADAIL 600
            EPLA+I+QIVD+FME +LIQQCT+FLLDALKNNRP+EG LQT LLEMNL+HAPQVADAIL
Sbjct: 541  EPLANISQIVDIFMENSLIQQCTSFLLDALKNNRPAEGLLQTWLLEMNLVHAPQVADAIL 600

Query: 601  GNQMFTHYDRAHIAQLCEKAGLLQRALEHFTDLYDIKRAVVHTHLLNPEWLVNYFGSLSV 660
            GN+MFTHYDRAHIAQLCEKAGLLQ+ALEH+TDLYDIKRAVVHTHLLNPEWLVN+FGSLSV
Sbjct: 601  GNKMFTHYDRAHIAQLCEKAGLLQQALEHYTDLYDIKRAVVHTHLLNPEWLVNFFGSLSV 660

Query: 661  EDSLECLRAMLSANIRQNLQICVQVASKYHEQLSTQSLIELFESFKSFEGLFYFLGSIVN 720
            EDS+ECL AMLSANIRQNLQ+CVQVASKYHEQL TQ+L+ELFESFKS++GLFYFLGSIVN
Sbjct: 661  EDSVECLHAMLSANIRQNLQLCVQVASKYHEQLGTQALVELFESFKSYKGLFYFLGSIVN 720

Query: 721  FSQDPDVHFKYIQAACKTGQIKEVERICRESNCYDPERVKNFLKEAKLTDQLPLIIVCDR 780
            FSQDPDVH KYIQAACKTGQIKEVERICRES+CY+PERVKNFLKEAKLTDQLPLIIVCDR
Sbjct: 721  FSQDPDVHLKYIQAACKTGQIKEVERICRESSCYNPERVKNFLKEAKLTDQLPLIIVCDR 780

Query: 781  FDFVHDLVLYLYRNNLQKYIEIYVQKVNPSRLPVVIGGLLDVDCSEDVIKNLILVVRGQF 840
            F FVHDLVLYLYRNNLQ+YIEIYVQKVNPSR P VIGGLLDVDCSE+VIK+LI+ VRGQF
Sbjct: 781  FGFVHDLVLYLYRNNLQRYIEIYVQKVNPSRTPAVIGGLLDVDCSEEVIKHLIMAVRGQF 840

Query: 841  STDELVAEVEKRNRLKLLLPWLEARIHEGCEEPATHNALAKIYIDSNNNPERFLRENPYY 900
            STDELVAEVEKRNRLKLLLPWLE++I EGCEEPATHNALAKIYIDSNN+PE FLREN YY
Sbjct: 841  STDELVAEVEKRNRLKLLLPWLESQIQEGCEEPATHNALAKIYIDSNNSPECFLRENAYY 900

Query: 901  DSRVVGKYCEKRDPHLACVAYERGQCDLELINVCNENSLFKSLSRYLVRRKDPELWGSVL 960
            DS VVG+YCEKRDPHLACVAYERGQCDLELI VCNENSLFKS +RYLV RKDPELW  VL
Sbjct: 901  DSSVVGRYCEKRDPHLACVAYERGQCDLELIKVCNENSLFKSEARYLVCRKDPELWAHVL 960

Query: 961  LESNPYRRPLIDQVVQTALSETQDPEEVSVTVKAFMTADLPNELIELLEKIVLDNSVFSE 1020
             E+NP RR LIDQVVQTALSET+DPEE+SVTVKAFMTADLPNELIELLEKIVLDNSVFSE
Sbjct: 961  EETNPSRRQLIDQVVQTALSETRDPEEISVTVKAFMTADLPNELIELLEKIVLDNSVFSE 1020

Query: 1021 HRNLQNLLILTAIKADRTRVMEYINRLDNYDAPDIANIAISNELFEEAFAIFRKFDVNTS 1080
            HRNLQNLLILTAIKADRTRVMEYI+RLDNYDA DIA+IA+S+ L+EEAF +F KFD+N S
Sbjct: 1021 HRNLQNLLILTAIKADRTRVMEYISRLDNYDALDIASIAVSSALYEEAFTVFHKFDMNAS 1080

Query: 1081 AVQVLIEHIGNLDRAYEFAERCNEPAVWSQLAKAQLQKGMVKEAIDSYIKADDPSSYMEV 1140
            A+QVLIEHIGNLDRAYEFAERCNEPAVWSQLA+AQLQK +VKEAI+SYI+ DDPSSY+EV
Sbjct: 1081 AIQVLIEHIGNLDRAYEFAERCNEPAVWSQLAQAQLQKDLVKEAINSYIRGDDPSSYLEV 1140

Query: 1141 VQAANTSGNWEELVKYLQMARKKARESYVETELIFALAKTNRLAELEEFINGPNNAHIQQ 1200
            VQ+A+ S NWE+LVK+LQMARKK RESY+ETELIFALAKT+R++ELE+FINGPNNAHIQQ
Sbjct: 1141 VQSASRSNNWEDLVKFLQMARKKGRESYIETELIFALAKTSRVSELEDFINGPNNAHIQQ 1200

Query: 1201 VGDRCYDEKMYDAAKLLYNNVSNFGRLASTLVHLGEYQAAVDGARKANSTRTWKEVCFAC 1260
            VGDRCY+E MY+AAKLLY+NVSNF RLASTLVHLGEYQAAVD +RKA+STRTWKEVCFAC
Sbjct: 1201 VGDRCYEEGMYEAAKLLYSNVSNFARLASTLVHLGEYQAAVDNSRKASSTRTWKEVCFAC 1260

Query: 1261 VDGKEFRLAQMCGLHIVVHADELEELINYYQDRGYFEELITMLEAALGLERAHMGMFTEL 1320
            +DG+EFR AQ+CGLHIV+HADELEEL+ YYQDRGYFEELI +LEAALGLERAHMGMFTEL
Sbjct: 1261 MDGQEFRFAQLCGLHIVIHADELEELMCYYQDRGYFEELILLLEAALGLERAHMGMFTEL 1320

Query: 1321 AILYSKFKPQKMREHLELFWSRVNIPKVLRAAEQAHLWAELVFLYDKYEEYDNAIITMMN 1380
            AILYSKFKPQKM EHLELFWSRVNIPKVLRAAEQAHLWAELVFLYDKYEEYDNA++TMM+
Sbjct: 1321 AILYSKFKPQKMLEHLELFWSRVNIPKVLRAAEQAHLWAELVFLYDKYEEYDNAVLTMMS 1380

Query: 1381 HPTDAWKEGQFKDIITKVANVELYYRAIQFYLEFKPLLLNDLLMVLSPRLDHTRAVNYFS 1440
            HPT+AWKEGQFKDIITKVANVEL YRA+QFYL++KPLL+NDLL+VLSPRLDHT  V++FS
Sbjct: 1381 HPTEAWKEGQFKDIITKVANVELCYRALQFYLDYKPLLINDLLLVLSPRLDHTWTVSFFS 1440

Query: 1441 KVKQLPLVKPYLRSVQNHNNKSVNESLNNLFITEEDYQALRTSIDAYDNFDNISLAQRLE 1500
            K  QLPLVKPYLRSVQ+HNNKSVNE+LN+L   EEDYQ LR SIDAYDNFDNISLAQ+LE
Sbjct: 1441 KAGQLPLVKPYLRSVQSHNNKSVNEALNHLLTEEEDYQGLRASIDAYDNFDNISLAQQLE 1500

Query: 1501 KHELIEFRRIAAYLFKGNNRWKQSVELCKKDSLYKDAMQYASESKDTELAEELLQWFLQE 1560
            KH+L+EFR IAAYL+KGNN W QSVELCKKD LYKDAMQ+A+ES+D ELA++LLQWFL+E
Sbjct: 1501 KHQLMEFRCIAAYLYKGNNWWAQSVELCKKDHLYKDAMQHAAESRDAELAQKLLQWFLEE 1560

Query: 1561 EKRECFGACLFTCYDLLRPDVVLETAWRHNIMDFAMPYFIQVMKEYLTKVDKLDASESLR 1620
             KRECF ACLFTCYDLLRPD+VLE AWRHN++D AMPYFIQVM+EYL+KVDKLDA ESLR
Sbjct: 1561 GKRECFAACLFTCYDLLRPDMVLELAWRHNLVDLAMPYFIQVMREYLSKVDKLDALESLR 1620

Query: 1621 KEEEQATETQPIVY 1634
            K+EE  TE  P+V+
Sbjct: 1621 KQEEHVTEPAPLVF 1634


>gi|242247001 clathrin, heavy polypeptide-like 1 isoform 2 [Homo
            sapiens]
          Length = 1583

 Score = 2610 bits (6766), Expect = 0.0
 Identities = 1309/1637 (79%), Positives = 1454/1637 (88%), Gaps = 63/1637 (3%)

Query: 1    MAQILPIRFQEHLQLQNLGINPANIGFSTLTMESDKFICIREKVGEQAQVVIIDMNDPSN 60
            MAQILP+RFQEH QLQNLGINPANIGFSTLTMESDKFICIREKVGEQAQV IIDM+DP  
Sbjct: 1    MAQILPVRFQEHFQLQNLGINPANIGFSTLTMESDKFICIREKVGEQAQVTIIDMSDPMA 60

Query: 61   PIRRPISADSAIMNPASKVIALKAGKTLQIFNIEMKSKMKAHTMTDDVTFWKWISLNTVA 120
            PIRRPISA+SAIMNPASKVIALKAGKTLQIFNIEMKSKMKAHTM ++V FWKW+S+NTVA
Sbjct: 61   PIRRPISAESAIMNPASKVIALKAGKTLQIFNIEMKSKMKAHTMAEEVIFWKWVSVNTVA 120

Query: 121  LVTDNAVYHWSMEGESQPVKMFDRHSSLAGCQIINYRTDAKQKWLLLTGISAQQNRVVGA 180
            LVT+ AVYHWSMEG+SQP+KMFDRH+SL GCQ+I+YRTD  QKWLLL GISAQQNRVVGA
Sbjct: 121  LVTETAVYHWSMEGDSQPMKMFDRHTSLVGCQVIHYRTDEYQKWLLLVGISAQQNRVVGA 180

Query: 181  MQLYSVDRKVSQPIEGHAASFAQFKMEGNAEESTLFCFAVRGQAGGKLHIIEVGTPPTGN 240
            MQLYSVDRKVSQPIEGHAA+FA+FKMEGNA+ +TLFCFAVR   GGKLHIIEVG P  GN
Sbjct: 181  MQLYSVDRKVSQPIEGHAAAFAEFKMEGNAKPATLFCFAVRNPTGGKLHIIEVGQPAAGN 240

Query: 241  QPFPKKAVDVFFPPEAQNDFPVAMQISEKHDVVFLITKYGYIHLYDLETGTCIYMNRISG 300
            QPF KKAVDVFFPPEAQNDFPVAMQI  KH V++LITKYGY+HLYDLE+G CI MNRIS 
Sbjct: 241  QPFVKKAVDVFFPPEAQNDFPVAMQIGAKHGVIYLITKYGYLHLYDLESGVCICMNRISA 300

Query: 301  ETIFVTAPHEATAGIIGVNRKGQVLSVCVEEENIIPYITNVLQNPDLALRMAVRNNLAGA 360
            +TIFVTAPH+ T+GIIGVN+KGQVLSVCVEE+NI+ Y TNVLQNPDL LR+AVR+NLAGA
Sbjct: 301  DTIFVTAPHKPTSGIIGVNKKGQVLSVCVEEDNIVNYATNVLQNPDLGLRLAVRSNLAGA 360

Query: 361  EELFARKFNALFAQGNYSEAAKVAANAPKGILRTPDTIRRFQSVPAQPGQTSPLLQYFGI 420
            E+LF RKFN LFAQG+Y+EAAKVAA+APKGILRT +T+++FQS+PAQ GQ SPLLQYFGI
Sbjct: 361  EKLFVRKFNTLFAQGSYAEAAKVAASAPKGILRTRETVQKFQSIPAQSGQASPLLQYFGI 420

Query: 421  LLDQGQLNKYESLELCRPVLQQGRKQLLEKWLKEDKLECSEELGDLVKSVDPTLALSVYL 480
            LLDQGQLNK ESLELC  VLQQGRKQLLEKWLKEDKLECSEELGDLVK+ DP LALSVYL
Sbjct: 421  LLDQGQLNKLESLELCHLVLQQGRKQLLEKWLKEDKLECSEELGDLVKTTDPMLALSVYL 480

Query: 481  RANVPNKVIQCFAETGQVQKIVLYAKKVGYTPDWIFLLRNVMRISPDQGQQFAQMLVQDE 540
            RANVP+KVIQCFAETGQ QKIVLYAKKVGYTPDWIFLLR VM+ISP+QG QF++MLVQDE
Sbjct: 481  RANVPSKVIQCFAETGQFQKIVLYAKKVGYTPDWIFLLRGVMKISPEQGLQFSRMLVQDE 540

Query: 541  EPLADITQIVDVFMEYNLIQQCTAFLLDALKNNRPSEGPLQTRLLEMNLMHAPQVADAIL 600
            EPLA+I+QIVD+FME +LIQQCT+FLLDALKNNRP+EG LQT LLEMNL+HAPQVADAIL
Sbjct: 541  EPLANISQIVDIFMENSLIQQCTSFLLDALKNNRPAEGLLQTWLLEMNLVHAPQVADAIL 600

Query: 601  GNQMFTHYDRAHIAQLCEKAGLLQRALEHFTDLYDIKRAVVHTHLLNPEWLVNYFGSLSV 660
            GN+MFTHYDRAHIAQLCEKAGLLQ+ALEH+TDLYDIKRAVVHTHLLNPEWLVN+FGSLSV
Sbjct: 601  GNKMFTHYDRAHIAQLCEKAGLLQQALEHYTDLYDIKRAVVHTHLLNPEWLVNFFGSLSV 660

Query: 661  EDSLECLRAMLSANIRQNLQICVQVASKYHEQLSTQSLIELFESFKSFEGLFYFLGSIVN 720
            EDS+ECL AMLSANIRQNLQ+CVQVASKYHEQL TQ+L+ELFESFKS++GLFYFLGSIVN
Sbjct: 661  EDSVECLHAMLSANIRQNLQLCVQVASKYHEQLGTQALVELFESFKSYKGLFYFLGSIVN 720

Query: 721  FSQDPDVHFKYIQAACKTGQIKEVERICRESNCYDPERVKNFLKEAKLTDQLPLIIVCDR 780
            FSQDPDVH KYIQAACKTGQIKEVERICRES+CY+PERVKNFLKEAKLTDQLPLIIVCDR
Sbjct: 721  FSQDPDVHLKYIQAACKTGQIKEVERICRESSCYNPERVKNFLKEAKLTDQLPLIIVCDR 780

Query: 781  FDFVHDLVLYLYRNNLQKYIEIYVQKVNPSRLPVVIGGLLDVDCSEDVIKNLILVVRGQF 840
            F FVHDLVLYLYRNNLQ+YIEIYVQKVNPSR P VIGGLLDVDCSE+VIK+LI+ VRGQF
Sbjct: 781  FGFVHDLVLYLYRNNLQRYIEIYVQKVNPSRTPAVIGGLLDVDCSEEVIKHLIMAVRGQF 840

Query: 841  STDELVAEVEKRNRLKLLLPWLEARIHEGCEEPATHNALAKIYIDSNNNPERFLRENPYY 900
            STDELVAEVEKRNRLKLLLPWLE++I EGCEEPATHNALAKIYIDSNN+PE FLREN YY
Sbjct: 841  STDELVAEVEKRNRLKLLLPWLESQIQEGCEEPATHNALAKIYIDSNNSPECFLRENAYY 900

Query: 901  DSRVVGKYCEKRDPHLACVAYERGQCDLELINVCNENSLFKSLSRYLVRRKDPELWGSVL 960
            DS VVG+YCEKRDPHLACVAYERGQCDLELI VCNENSLFKS +RYLV RKDPELW  VL
Sbjct: 901  DSSVVGRYCEKRDPHLACVAYERGQCDLELIKVCNENSLFKSEARYLVCRKDPELWAHVL 960

Query: 961  LESNPYRRPLIDQVVQTALSETQDPEEVSVTVKAFMTADLPNELIELLEKIVLDNSVFSE 1020
             E+NP RR LIDQVVQTALSET+DPEE+SVTVKAFMTADLPNELIELLEKIVLDNSVFSE
Sbjct: 961  EETNPSRRQLIDQVVQTALSETRDPEEISVTVKAFMTADLPNELIELLEKIVLDNSVFSE 1020

Query: 1021 HRNLQNLLILTAIKADRTRVMEYINRLDNYDAPDIANIAISNELFEEAFAIFRKFDVNTS 1080
            HRNLQNLLILTAIKADRTRVMEYI+RLDNYDA DIA+IA+S+ L+EEAF +F KFD+N S
Sbjct: 1021 HRNLQNLLILTAIKADRTRVMEYISRLDNYDALDIASIAVSSALYEEAFTVFHKFDMNAS 1080

Query: 1081 AVQVLIEHIGNLDRAYEFAERCNEPAVWSQLAKAQLQKGMVKEAIDSYIKADDPSSYMEV 1140
            A+QVLIEHIGNLDRAYEFAERCNEPAVWSQLA+AQLQK +VKEAI+SYI+ DDPSSY+EV
Sbjct: 1081 AIQVLIEHIGNLDRAYEFAERCNEPAVWSQLAQAQLQKDLVKEAINSYIRGDDPSSYLEV 1140

Query: 1141 VQAANTSGNWEELVKYLQMARKKARESYVETELIFALAKTNRLAELEEFINGPNNAHIQQ 1200
            VQ+A+ S NWE+LVK+LQMARKK RESY+ETELIFALAKT+R++ELE+FINGPNNAHIQQ
Sbjct: 1141 VQSASRSNNWEDLVKFLQMARKKGRESYIETELIFALAKTSRVSELEDFINGPNNAHIQQ 1200

Query: 1201 VGDRCYDEKMYDAAKLLYNNVSNFGRLASTLVHLGEYQAAVDGARKANSTRTWKEVCFAC 1260
            VGDRCY+E MY+AAKLLY+NVSNF RLASTLVHLGEYQAAVD +RKA+STRTWKEVCFAC
Sbjct: 1201 VGDRCYEEGMYEAAKLLYSNVSNFARLASTLVHLGEYQAAVDNSRKASSTRTWKEVCFAC 1260

Query: 1261 VDGKEFRLAQMCGLHIVVHADELEELINYYQDRGYFEELITMLEAALGLERAHMGMFTEL 1320
            +DG+EFR AQ+CGLHIV+HADELEEL+ YYQDRGYFEELI +LEAALGLERAHMGMFTEL
Sbjct: 1261 MDGQEFRFAQLCGLHIVIHADELEELMCYYQDRGYFEELILLLEAALGLERAHMGMFTEL 1320

Query: 1321 AILYSKFKPQKMREHLELFWSRVNIPKVLRAAEQAHLWAELVFLYDKYEEYDNAIITMMN 1380
            AILYSKFKPQKM EHLELFWSRVNIPKVLRAAEQAHLWAELVFLYDKYEEYDNA++TMM+
Sbjct: 1321 AILYSKFKPQKMLEHLELFWSRVNIPKVLRAAEQAHLWAELVFLYDKYEEYDNAVLTMMS 1380

Query: 1381 HPTDAWKEGQFKDIITKVANVELYYRAIQFYLEFKPLLLNDLLMVLSPRLDHTRAVNYFS 1440
            HPT+AWKEGQFKDIITKVANVEL YRA+QFYL++KPLL+NDLL+VLSPRLDHT  V++FS
Sbjct: 1381 HPTEAWKEGQFKDIITKVANVELCYRALQFYLDYKPLLINDLLLVLSPRLDHTWTVSFFS 1440

Query: 1441 KVKQLPLVKPYLRSVQNHNNKSVNESLNNLFITEEDYQ-ALRTSIDAYDNFDNISLAQRL 1499
            K  QLPLVKPYLRSVQ+HNNKSVNE+LN+L   EEDYQ A++ + ++ D      LAQ+L
Sbjct: 1441 KAGQLPLVKPYLRSVQSHNNKSVNEALNHLLTEEEDYQDAMQHAAESRD----AELAQKL 1496

Query: 1500 EKHELIEFRR--IAAYLFKGNNRWKQSVELCKKDSLYKDAMQYASESKDTELAEELLQWF 1557
             +  L E +R   AA LF          +L + D + + A ++        L +  + +F
Sbjct: 1497 LQWFLEEGKRECFAACLF-------TCYDLLRPDMVLELAWRH-------NLVDLAMPYF 1542

Query: 1558 LQEEKRECFGACLFTCYDLLRPDVVLETAWRHNIMDFAMPYFIQVMKEYLTKVDKLDASE 1617
            +Q                                          VM+EYL+KVDKLDA E
Sbjct: 1543 IQ------------------------------------------VMREYLSKVDKLDALE 1560

Query: 1618 SLRKEEEQATETQPIVY 1634
            SLRK+EE  TE  P+V+
Sbjct: 1561 SLRKQEEHVTEPAPLVF 1577


>gi|208022639 hypothetical protein LOC130162 isoform 2 [Homo
           sapiens]
          Length = 464

 Score = 68.6 bits (166), Expect = 5e-11
 Identities = 46/160 (28%), Positives = 78/160 (48%), Gaps = 15/160 (9%)

Query: 364 FARKFNALFAQGNYSEAAKVAANAPKGILRTPDTIRRFQSVPAQPGQTSPLLQYFGILLD 423
           +  +FN L + G Y +AA  AAN+P+ ILR   T+  F++V    G+  PLL +F  L  
Sbjct: 175 YIERFNELISLGEYEKAACYAANSPRRILRNIGTMNTFKAVGKIRGKPLPLLLFFEALFI 234

Query: 424 QGQ-----LNKYESLELCRPVLQQGRKQLLEKWLKEDKLECSEELGDLV----------K 468
                   ++   +LE  +  L + R  L+  W+ +++L  SEE GD++          K
Sbjct: 235 TSHAFPCPVDAALTLEGIKCGLSEKRLDLVTNWVTQERLTFSEEAGDVICDYGEQDTYNK 294

Query: 469 SVDPTLALSVYLRANVPNKVIQCFAETGQVQKIVLYAKKV 508
           +    LA  VY    +  K I C  + GQ  +++ Y +++
Sbjct: 295 AKCLALAQIVYSECGLHKKAILCLCKQGQTHRVMEYIQQL 334


>gi|208022637 hypothetical protein LOC130162 isoform 1 [Homo
           sapiens]
          Length = 586

 Score = 68.6 bits (166), Expect = 5e-11
 Identities = 46/160 (28%), Positives = 78/160 (48%), Gaps = 15/160 (9%)

Query: 364 FARKFNALFAQGNYSEAAKVAANAPKGILRTPDTIRRFQSVPAQPGQTSPLLQYFGILLD 423
           +  +FN L + G Y +AA  AAN+P+ ILR   T+  F++V    G+  PLL +F  L  
Sbjct: 297 YIERFNELISLGEYEKAACYAANSPRRILRNIGTMNTFKAVGKIRGKPLPLLLFFEALFI 356

Query: 424 QGQ-----LNKYESLELCRPVLQQGRKQLLEKWLKEDKLECSEELGDLV----------K 468
                   ++   +LE  +  L + R  L+  W+ +++L  SEE GD++          K
Sbjct: 357 TSHAFPCPVDAALTLEGIKCGLSEKRLDLVTNWVTQERLTFSEEAGDVICDYGEQDTYNK 416

Query: 469 SVDPTLALSVYLRANVPNKVIQCFAETGQVQKIVLYAKKV 508
           +    LA  VY    +  K I C  + GQ  +++ Y +++
Sbjct: 417 AKCLALAQIVYSECGLHKKAILCLCKQGQTHRVMEYIQQL 456


>gi|56243599 WD repeat domain 35 isoform 2 [Homo sapiens]
          Length = 1170

 Score = 36.2 bits (82), Expect = 0.27
 Identities = 45/174 (25%), Positives = 70/174 (40%), Gaps = 23/174 (13%)

Query: 1083 QVLIEHIGNLDRAYEFAERCNEPAVWSQLAKAQLQKGMVKEAIDSYIKADD--------- 1133
            + LIE +G  D A +F E    P +W  LA+A LQK  +  A  ++++  D         
Sbjct: 664  RALIEKVGIKD-ASQFIEDNPHPRLWRLLAEAALQKLDLYTAEQAFVRCKDYQGIKFVKR 722

Query: 1134 ----PSSYMEVVQAANTSGNWEELVK-YLQMARKK----ARESYVETELIFALAKTNRLA 1184
                 S  M+  +     G +EE  + YL+M R+      R    +   +  L KT    
Sbjct: 723  LGKLLSESMKQAEVVGYFGRFEEAERTYLEMDRRDLAIGLRLKLGDWFRVLQLLKTGSGD 782

Query: 1185 ELEEFINGPNNAHIQQVGDRCYDEKMYDAAKLLYNNVSNFGRLASTLVHLGEYQ 1238
              +  +   NNA    +GD   D + +  A   Y    N  RLA     L +Y+
Sbjct: 783  ADDSLLEQANNA----IGDYFADRQKWLNAVQYYVQGRNQERLAECYYMLEDYE 832


>gi|55743161 WD repeat domain 35 isoform 1 [Homo sapiens]
          Length = 1181

 Score = 36.2 bits (82), Expect = 0.27
 Identities = 45/174 (25%), Positives = 70/174 (40%), Gaps = 23/174 (13%)

Query: 1083 QVLIEHIGNLDRAYEFAERCNEPAVWSQLAKAQLQKGMVKEAIDSYIKADD--------- 1133
            + LIE +G  D A +F E    P +W  LA+A LQK  +  A  ++++  D         
Sbjct: 675  RALIEKVGIKD-ASQFIEDNPHPRLWRLLAEAALQKLDLYTAEQAFVRCKDYQGIKFVKR 733

Query: 1134 ----PSSYMEVVQAANTSGNWEELVK-YLQMARKK----ARESYVETELIFALAKTNRLA 1184
                 S  M+  +     G +EE  + YL+M R+      R    +   +  L KT    
Sbjct: 734  LGKLLSESMKQAEVVGYFGRFEEAERTYLEMDRRDLAIGLRLKLGDWFRVLQLLKTGSGD 793

Query: 1185 ELEEFINGPNNAHIQQVGDRCYDEKMYDAAKLLYNNVSNFGRLASTLVHLGEYQ 1238
              +  +   NNA    +GD   D + +  A   Y    N  RLA     L +Y+
Sbjct: 794  ADDSLLEQANNA----IGDYFADRQKWLNAVQYYVQGRNQERLAECYYMLEDYE 843


>gi|7706127 core 2 beta-1,6-N-acetylglucosaminyltransferase 3 [Homo
            sapiens]
          Length = 453

 Score = 35.4 bits (80), Expect = 0.47
 Identities = 42/147 (28%), Positives = 60/147 (40%), Gaps = 17/147 (11%)

Query: 1468 NNLFITEEDYQALRTSIDAYDN----FDNISLAQRLEKHELIEFRRIAAYL------FKG 1517
            +N++    D +A  T   A +N    F NI +A +LE  E     R+ A L       K 
Sbjct: 157  HNIYCIHYDRKAPDTFKVAMNNLAKCFSNIFIASKLEAVEYAHISRLQADLNCLSDLLKS 216

Query: 1518 NNRWKQSVELCKKDSLYKDAMQYASESKDTELAEELLQWFLQEEKRECFGACLFTCYDLL 1577
            + +WK  + LC +D   K   +  SE K    A  L        K E      FT +  L
Sbjct: 217  SIQWKYVINLCGQDFPLKSNFELVSELKKLNGANMLETVKPPNSKLE-----RFTYHHEL 271

Query: 1578 R--PDVVLETAWRHNIMDFAMPYFIQV 1602
            R  P   ++   R NI   A P+ IQ+
Sbjct: 272  RRVPYEYVKLPIRTNISKEAPPHNIQI 298


>gi|114199473 vacuolar protein sorting 41 isoform 2 [Homo sapiens]
          Length = 829

 Score = 33.1 bits (74), Expect = 2.3
 Identities = 16/83 (19%), Positives = 38/83 (45%)

Query: 1036 DRTRVMEYINRLDNYDAPDIANIAISNELFEEAFAIFRKFDVNTSAVQVLIEHIGNLDRA 1095
            DR  ++ ++    +        I       EE   +  +   + SA+++++E + ++D+A
Sbjct: 599  DRPNLLPFLRDSTHCPLEKALEICQQRNFVEETVYLLSRMGNSRSALKMIMEELHDVDKA 658

Query: 1096 YEFAERCNEPAVWSQLAKAQLQK 1118
             EFA+  ++  +W  L    + K
Sbjct: 659  IEFAKEQDDGELWEDLILYSIDK 681


>gi|114199475 vacuolar protein sorting 41 isoform 1 [Homo sapiens]
          Length = 854

 Score = 33.1 bits (74), Expect = 2.3
 Identities = 16/83 (19%), Positives = 38/83 (45%)

Query: 1036 DRTRVMEYINRLDNYDAPDIANIAISNELFEEAFAIFRKFDVNTSAVQVLIEHIGNLDRA 1095
            DR  ++ ++    +        I       EE   +  +   + SA+++++E + ++D+A
Sbjct: 624  DRPNLLPFLRDSTHCPLEKALEICQQRNFVEETVYLLSRMGNSRSALKMIMEELHDVDKA 683

Query: 1096 YEFAERCNEPAVWSQLAKAQLQK 1118
             EFA+  ++  +W  L    + K
Sbjct: 684  IEFAKEQDDGELWEDLILYSIDK 706


>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin (with
            transmembrane signal), 1 [Homo sapiens]
          Length = 3259

 Score = 32.3 bits (72), Expect = 4.0
 Identities = 98/512 (19%), Positives = 194/512 (37%), Gaps = 65/512 (12%)

Query: 901  DSRVVGKYCEKRDPHLACVAYERGQCDLELINVCNENSLFKSLSRYLVRRKDPELWGSVL 960
            + +++     K +     +A  R Q D E+          K L   L + ++  +   VL
Sbjct: 2381 EQKIISLLSGKEEAIQVAIAELRQQHDKEI----------KELENLLSQEEEENI---VL 2427

Query: 961  LESNPYRRPLIDQVVQTALSETQDPEEVSVTVKAFMTADLPNELIELLEKIVLDNSVFSE 1020
             E N       +Q+++T  +  ++  +    + +F+ +   + L    ++IV D     E
Sbjct: 2428 EEENKKAVDKTNQLMETLKTIKKENIQQKAQLDSFVKS--MSSLQNDRDRIVGDYQQLEE 2485

Query: 1021 HRNLQNLL----ILTAIKADRTRVMEYINRLDNY-DAPDIANIAISNELFEEAFAIFRKF 1075
             R+L  +L    ++    A+  ++ E I  L ++ D  +  N  +  EL +    + +  
Sbjct: 2486 -RHLSIILEKDQLIQEAAAENNKLKEEIRGLRSHMDDLNSENAKLDAELIQYREDLNQVI 2544

Query: 1076 DVNTSAVQVLIE-----------HIGNLDRAYEFAERCNEPAVWSQLAKAQLQKGMVKEA 1124
             +  S  + L+E               L+   + +E  NE    S  A  + ++ + KE 
Sbjct: 2545 TIKDSQQKQLLEVQLQQNKELENKYAKLEEKLKESEEANEDLRRSFNALQEEKQDLSKEI 2604

Query: 1125 IDSYIKADDPSSYMEVVQAANTSGNWEELVKYLQMARKKARESYVETELIFALAKTNRLA 1184
                +     +  +  +Q   T G        L  A+ K +E  V        +   R+A
Sbjct: 2605 ESLKVSISQLTRQVTALQEEGTLG--------LYHAQLKVKEEEVHRLSALFSSSQKRIA 2656

Query: 1185 ELEEFINGPNNAHIQQVGDRCYDEKMYDAAKLLYNNVSNFG--------RLASTLVHLGE 1236
            ELEE +        ++VG+   ++K+    K L+++             R+A     L E
Sbjct: 2657 ELEEELVCVQKEAAKKVGE--IEDKLKKELKHLHHDAGIMRNETETAEERVAELARDLVE 2714

Query: 1237 YQAAVDGARKANSTRTWKEVCFACVDGKEFRLAQMCGLHIVVHADELEELINYYQDRGYF 1296
             +  +    K N   T +   F    G+     Q    H     +EL+EL   Y      
Sbjct: 2715 MEQKLLMVTKENKGLTAQIQSF----GRSMSSLQNSRDHA---NEELDELKRKYD--ASL 2765

Query: 1297 EELITMLEAALGLERAHMGMFTELAILYSKFKPQKMREHLELFWSRVNIPKVLRAAEQAH 1356
            +EL  + E  L L R    + +E A   +  +   +  HLE    ++N   + +  +  H
Sbjct: 2766 KELAQLKEQGL-LNRERDALLSETAFSMNSTEENSL-SHLE----KLNQQLLSKDEQLLH 2819

Query: 1357 LWAELVFLYDKYEEYDNAIITMMNHPTDAWKE 1388
            L ++L   Y++ + +  A+ ++ N     W E
Sbjct: 2820 LSSQLEDSYNQVQSFSKAMASLQNERDHLWNE 2851


>gi|194294521 intersectin 2 isoform 1 [Homo sapiens]
          Length = 1697

 Score = 32.3 bits (72), Expect = 4.0
 Identities = 28/107 (26%), Positives = 53/107 (49%), Gaps = 11/107 (10%)

Query: 1462 SVNESLNNLFITEEDYQALRTSIDAYDNFDNISLAQ--RLEKHELIEFRRIAAYLFKGNN 1519
            S+   LNNLF+  ++ +      + Y N   ++L Q  ++++ +L E  R    L +   
Sbjct: 635  SLLSCLNNLFLLLKELR------ETY-NTQQLALEQLYKIKRDKLKEIERKRLELMQKKK 687

Query: 1520 RWKQSVELCK--KDSLYKDAMQYASESKDTELAEELLQWFLQEEKRE 1564
               ++    K  K++L+K+ ++   E K   L EE  Q  +QEE+R+
Sbjct: 688  LEDEAARKAKQGKENLWKENLRKEEEEKQKRLQEEKTQEKIQEEERK 734


>gi|194294525 intersectin 2 isoform 2 [Homo sapiens]
          Length = 1249

 Score = 32.3 bits (72), Expect = 4.0
 Identities = 28/107 (26%), Positives = 53/107 (49%), Gaps = 11/107 (10%)

Query: 1462 SVNESLNNLFITEEDYQALRTSIDAYDNFDNISLAQ--RLEKHELIEFRRIAAYLFKGNN 1519
            S+   LNNLF+  ++ +      + Y N   ++L Q  ++++ +L E  R    L +   
Sbjct: 635  SLLSCLNNLFLLLKELR------ETY-NTQQLALEQLYKIKRDKLKEIERKRLELMQKKK 687

Query: 1520 RWKQSVELCK--KDSLYKDAMQYASESKDTELAEELLQWFLQEEKRE 1564
               ++    K  K++L+K+ ++   E K   L EE  Q  +QEE+R+
Sbjct: 688  LEDEAARKAKQGKENLWKENLRKEEEEKQKRLQEEKTQEKIQEEERK 734


>gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo
            sapiens]
          Length = 1935

 Score = 32.0 bits (71), Expect = 5.2
 Identities = 21/70 (30%), Positives = 35/70 (50%), Gaps = 5/70 (7%)

Query: 947  LVRRKDPELWGSVLLESNPYRRPLIDQVVQTALSETQDPEEVSVTVKAF----MTADLPN 1002
            ++  K PEL   +L+ +NPY    I Q  +T ++   D EE+  T  AF     T++  N
Sbjct: 289  ILSNKKPELLDMLLITNNPYDYAFISQ-GETTVASIDDAEELMATDNAFDVLGFTSEEKN 347

Query: 1003 ELIELLEKIV 1012
             + +L   I+
Sbjct: 348  SMYKLTGAIM 357


>gi|21361320 TRK-fused [Homo sapiens]
          Length = 400

 Score = 31.6 bits (70), Expect = 6.8
 Identities = 20/49 (40%), Positives = 26/49 (53%), Gaps = 5/49 (10%)

Query: 1629 TQPIVYGQPQLMLTA--GPSVAVPPQAPFGYGYTAPPYGQ--PQPGFGY 1673
            +QP  Y QP+   T+  G ++  PP  P  Y    PP+GQ   QPG GY
Sbjct: 352  SQPGAY-QPRPGFTSLPGSTMTPPPSGPNPYARNRPPFGQGYTQPGPGY 399


>gi|56090139 TRK-fused [Homo sapiens]
          Length = 400

 Score = 31.6 bits (70), Expect = 6.8
 Identities = 20/49 (40%), Positives = 26/49 (53%), Gaps = 5/49 (10%)

Query: 1629 TQPIVYGQPQLMLTA--GPSVAVPPQAPFGYGYTAPPYGQ--PQPGFGY 1673
            +QP  Y QP+   T+  G ++  PP  P  Y    PP+GQ   QPG GY
Sbjct: 352  SQPGAY-QPRPGFTSLPGSTMTPPPSGPNPYARNRPPFGQGYTQPGPGY 399


>gi|72534736 zinc finger protein 613 isoform 1 [Homo sapiens]
          Length = 617

 Score = 31.6 bits (70), Expect = 6.8
 Identities = 30/99 (30%), Positives = 44/99 (44%), Gaps = 18/99 (18%)

Query: 865 RIHEGCEEPATHNALAKIYIDS---NNNPERFLRENPYYDSRVVGKYCEKRDPHLACVAY 921
           RIH G E+P T +   K + D    N +      E PY  S      C K   HL+C+ Y
Sbjct: 476 RIHTG-EKPYTCSDCGKAFRDKSCLNRHRRTHTGERPYGCSD-----CGKAFSHLSCLVY 529

Query: 922 ERGQC--------DLELINVCNENSLFKSLSRYLVRRKD 952
            +G           ++L N C+E+    S +R L++ KD
Sbjct: 530 HKGMLHAREKCVGSVKLENPCSESHSL-SHTRDLIQDKD 567


>gi|21362003 zinc finger protein 613 isoform 2 [Homo sapiens]
          Length = 581

 Score = 31.6 bits (70), Expect = 6.8
 Identities = 30/99 (30%), Positives = 44/99 (44%), Gaps = 18/99 (18%)

Query: 865 RIHEGCEEPATHNALAKIYIDS---NNNPERFLRENPYYDSRVVGKYCEKRDPHLACVAY 921
           RIH G E+P T +   K + D    N +      E PY  S      C K   HL+C+ Y
Sbjct: 440 RIHTG-EKPYTCSDCGKAFRDKSCLNRHRRTHTGERPYGCSD-----CGKAFSHLSCLVY 493

Query: 922 ERGQC--------DLELINVCNENSLFKSLSRYLVRRKD 952
            +G           ++L N C+E+    S +R L++ KD
Sbjct: 494 HKGMLHAREKCVGSVKLENPCSESHSL-SHTRDLIQDKD 531


>gi|154277118 spectrin repeat containing, nuclear envelope 1 isoform 4
            [Homo sapiens]
          Length = 3321

 Score = 31.2 bits (69), Expect = 8.8
 Identities = 32/132 (24%), Positives = 54/132 (40%), Gaps = 8/132 (6%)

Query: 1117 QKGMVKEAIDSYIKADDPSSYMEVVQAANTSGNWEELVKYLQMARKKARESYVETELIFA 1176
            Q  ++K+ + +YI ADD S   E V+       WEEL   L + R++  E   E  +   
Sbjct: 2254 QLSLLKDTLSAYISADDISILNERVELLQR--QWEELCHQLSLRRQQIGERLNEWAVF-- 2309

Query: 1177 LAKTNRLAELEEFINGPNNAHIQQVGDRCYDEKMYDAAKLLYNNVSNFGRLASTLVHLGE 1236
               + +  EL E++     + + Q GD   +E +    K     ++        L  +GE
Sbjct: 2310 ---SEKNKELCEWLT-QMESKVSQNGDILIEEMIEKLKKDYQEEIAIAQENKIQLQQMGE 2365

Query: 1237 YQAAVDGARKAN 1248
              A      KA+
Sbjct: 2366 RLAKASHESKAS 2377


>gi|23097308 spectrin repeat containing, nuclear envelope 1 isoform 2
            [Homo sapiens]
          Length = 8749

 Score = 31.2 bits (69), Expect = 8.8
 Identities = 32/132 (24%), Positives = 54/132 (40%), Gaps = 8/132 (6%)

Query: 1117 QKGMVKEAIDSYIKADDPSSYMEVVQAANTSGNWEELVKYLQMARKKARESYVETELIFA 1176
            Q  ++K+ + +YI ADD S   E V+       WEEL   L + R++  E   E  +   
Sbjct: 7659 QLSLLKDTLSAYISADDISILNERVELLQR--QWEELCHQLSLRRQQIGERLNEWAVF-- 7714

Query: 1177 LAKTNRLAELEEFINGPNNAHIQQVGDRCYDEKMYDAAKLLYNNVSNFGRLASTLVHLGE 1236
               + +  EL E++     + + Q GD   +E +    K     ++        L  +GE
Sbjct: 7715 ---SEKNKELCEWLT-QMESKVSQNGDILIEEMIEKLKKDYQEEIAIAQENKIQLQQMGE 7770

Query: 1237 YQAAVDGARKAN 1248
              A      KA+
Sbjct: 7771 RLAKASHESKAS 7782


>gi|154277116 spectrin repeat containing, nuclear envelope 1 isoform 1
            [Homo sapiens]
          Length = 8797

 Score = 31.2 bits (69), Expect = 8.8
 Identities = 32/132 (24%), Positives = 54/132 (40%), Gaps = 8/132 (6%)

Query: 1117 QKGMVKEAIDSYIKADDPSSYMEVVQAANTSGNWEELVKYLQMARKKARESYVETELIFA 1176
            Q  ++K+ + +YI ADD S   E V+       WEEL   L + R++  E   E  +   
Sbjct: 7730 QLSLLKDTLSAYISADDISILNERVELLQR--QWEELCHQLSLRRQQIGERLNEWAVF-- 7785

Query: 1177 LAKTNRLAELEEFINGPNNAHIQQVGDRCYDEKMYDAAKLLYNNVSNFGRLASTLVHLGE 1236
               + +  EL E++     + + Q GD   +E +    K     ++        L  +GE
Sbjct: 7786 ---SEKNKELCEWLT-QMESKVSQNGDILIEEMIEKLKKDYQEEIAIAQENKIQLQQMGE 7841

Query: 1237 YQAAVDGARKAN 1248
              A      KA+
Sbjct: 7842 RLAKASHESKAS 7853


>gi|55770846 catenin, alpha 2 [Homo sapiens]
          Length = 905

 Score = 31.2 bits (69), Expect = 8.8
 Identities = 61/272 (22%), Positives = 106/272 (38%), Gaps = 30/272 (11%)

Query: 959  VLLESNPYRRPLIDQVVQ----TALSETQDPEEVSVTVKAFMTADLPNELIELLEKIVLD 1014
            ++ E N  R+ L D + +    T   E  DP  +++      T DL  +L + +   + D
Sbjct: 331  IVAECNAVRQALQDLLSEYMNNTGRKEKGDPLNIAIDKMTKKTRDLRRQLRKAVMDHISD 390

Query: 1015 NSVFSEHRNLQNLLILTAIKADRTR-VMEY--INRLDNYDAPDIANIAISNELFEEAFAI 1071
            + +     N+  L+++ A K+   + V EY  + R       ++AN+A S    EE   +
Sbjct: 391  SFL---ETNVPLLVLIEAAKSGNEKEVKEYAQVFREHANKLVEVANLACSISNNEEGVKL 447

Query: 1072 FRKF--DVNTSAVQVLIEHIGNLDRAYEFAERCNEPAVWSQLAKAQLQKGMVKEAIDSYI 1129
             R     +++   QV+   +    R      + N      Q  K   Q  ++ EA+D   
Sbjct: 448  VRMAATQIDSLCPQVINAALTLAARPQSKVAQDNMDVFKDQWEK---QVRVLTEAVDDIT 504

Query: 1130 KADDPSSYMEVVQAANTSGNWEELVKYLQMARKKARESYVETELIFALAKTNRLAELEEF 1189
              DD  S  E             +++ +       +E  V+T    A A   R A +   
Sbjct: 505  SVDDFLSVSE-----------NHILEDVNKCVIALQEGDVDTLDRTAGAIRGRAARVIHI 553

Query: 1190 INGPNNAHIQQVGDRCYDEKMYDAAKLLYNNV 1221
            IN    A ++      Y EK+ +A KLL   V
Sbjct: 554  IN----AEMENYEAGVYTEKVLEATKLLSETV 581


>gi|148727333 adenylate kinase 7 [Homo sapiens]
          Length = 723

 Score = 31.2 bits (69), Expect = 8.8
 Identities = 41/167 (24%), Positives = 64/167 (38%), Gaps = 26/167 (15%)

Query: 1000 LPNELIELLEKIVLDNSVFSEHRNLQNLLILTAIKADRTRVMEYINRLDNYDAPDIANIA 1059
            L   +I L E IV     +S+ R L+ L     I  D   V  Y + L+      I  I 
Sbjct: 531  LKERVINLPESIVAGTH-YSQDRFLRALSNYRDINIDDETVFNYFDELE------IHPIH 583

Query: 1060 ISNELFEEAFAIFRKFDVNTSAVQVLIEHIGNLDRAYEFAERCNEPAVWSQLAKAQLQKG 1119
            I     E+A         N  A++ LI+ IG   R Y   +            KA+ ++ 
Sbjct: 584  IDVGKLEDA--------QNRLAIKQLIKEIGE-PRNYGLTDE----------EKAEEERK 624

Query: 1120 MVKEAIDSYIKADDPSSYMEVVQAANTSGNWEELVKYLQMARKKARE 1166
              +E +      +    + E V+ A     WEE  K L+  +++ RE
Sbjct: 625  AAEERLAREAAEEAEREHQEAVEMAEKIARWEEWNKRLEEVKREERE 671


>gi|134142824 forkhead box D2 [Homo sapiens]
          Length = 495

 Score = 31.2 bits (69), Expect = 8.8
 Identities = 21/75 (28%), Positives = 29/75 (38%), Gaps = 15/75 (20%)

Query: 1611 DKLDASESLRKEE----EQATETQPIVYGQPQLMLTAGPSVAVPPQA-----------PF 1655
            D  D    LR+ +    +      P  +  P+L+L  G + A  P A            +
Sbjct: 209  DMFDNGSFLRRRKRFKRQPLPPPHPHPHPHPELLLRGGAAAAGDPGAFLPGFAAYGAYGY 268

Query: 1656 GYGYTAPPYGQPQPG 1670
            GYG   P YG P PG
Sbjct: 269  GYGLALPAYGAPPPG 283


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.135    0.398 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 60,071,815
Number of Sequences: 37866
Number of extensions: 2631646
Number of successful extensions: 6759
Number of sequences better than 10.0: 24
Number of HSP's better than 10.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 17
Number of HSP's that attempted gapping in prelim test: 6709
Number of HSP's gapped (non-prelim): 45
length of query: 1675
length of database: 18,247,518
effective HSP length: 116
effective length of query: 1559
effective length of database: 13,855,062
effective search space: 21600041658
effective search space used: 21600041658
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 69 (31.2 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.