Search of human proteins with 47419907

Search of human proteins with 47419907

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|47419907 T-box 3 protein isoform 2 [Homo sapiens]
         (743 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|47419907 T-box 3 protein isoform 2 [Homo sapiens]                 1481   0.0  
gi|47419905 T-box 3 protein isoform 1 [Homo sapiens]                 1425   0.0  
gi|197333868 T-box 2 [Homo sapiens]                                   675   0.0  
gi|18201894 T-box 5 isoform 3 [Homo sapiens]                          239   5e-63
gi|18201892 T-box 5 isoform 1 [Homo sapiens]                          239   5e-63
gi|31652232 T-box 5 isoform 1 [Homo sapiens]                          239   5e-63
gi|18129690 T-box 4 [Homo sapiens]                                    238   1e-62
gi|18201896 T-box 5 isoform 2 [Homo sapiens]                          236   4e-62
gi|117676399 T-box transcription factor TBX20 [Homo sapiens]          236   6e-62
gi|5174711 T-box 1 isoform B [Homo sapiens]                           221   2e-57
gi|18104952 T-box 1 isoform C [Homo sapiens]                          221   2e-57
gi|18104950 T-box 1 isoform A [Homo sapiens]                          221   2e-57
gi|32567784 T-box 10 [Homo sapiens]                                   220   3e-57
gi|18201900 T-box 6 [Homo sapiens]                                    218   2e-56
gi|122937456 T-box 18 [Homo sapiens]                                  213   4e-55
gi|55770860 T-box 15 [Homo sapiens]                                   206   6e-53
gi|122937388 MAX gene associated [Homo sapiens]                       197   4e-50
gi|158187509 T-box 22 isoform 1 [Homo sapiens]                        193   6e-49
gi|18375603 T-box 22 isoform 1 [Homo sapiens]                         193   6e-49
gi|4507339 transcription factor T [Homo sapiens]                      186   9e-47
gi|5730081 T-box, brain, 1 [Homo sapiens]                             181   2e-45
gi|7019549 T-box 21 [Homo sapiens]                                    177   4e-44
gi|22538470 eomesodermin [Homo sapiens]                               174   3e-43
gi|4827024 T-box 19 [Homo sapiens]                                    166   9e-41
gi|158187511 T-box 22 isoform 2 [Homo sapiens]                        154   2e-37
gi|146219843 Snf2-related CBP activator protein [Homo sapiens]         54   7e-07
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]     46   1e-04
gi|7662228 synaptosomal-associated protein, 91kDa homolog [Homo ...    45   2e-04
gi|19111150 angiomotin isoform 2 [Homo sapiens]                        44   7e-04
gi|166064029 angiomotin isoform 1 [Homo sapiens]                       44   7e-04

>gi|47419907 T-box 3 protein isoform 2 [Homo sapiens]
          Length = 743

 Score = 1481 bits (3833), Expect = 0.0
 Identities = 743/743 (100%), Positives = 743/743 (100%)

Query: 1   MSLSMRDPVIPGTSMAYHPFLPHRAPDFAMSAVLGHQPPFFPALTLPPNGAAALSLPGAL 60
           MSLSMRDPVIPGTSMAYHPFLPHRAPDFAMSAVLGHQPPFFPALTLPPNGAAALSLPGAL
Sbjct: 1   MSLSMRDPVIPGTSMAYHPFLPHRAPDFAMSAVLGHQPPFFPALTLPPNGAAALSLPGAL 60

Query: 61  AKPIMDQLVGAAETGIPFSSLGPQAHLRPLKTMEPEEEVEDDPKVHLEAKELWDQFHKRG 120
           AKPIMDQLVGAAETGIPFSSLGPQAHLRPLKTMEPEEEVEDDPKVHLEAKELWDQFHKRG
Sbjct: 61  AKPIMDQLVGAAETGIPFSSLGPQAHLRPLKTMEPEEEVEDDPKVHLEAKELWDQFHKRG 120

Query: 121 TEMVITKSGRRMFPPFKVRCSGLDKKAKYILLMDIIAADDCRYKFHNSRWMVAGKADPEM 180
           TEMVITKSGRRMFPPFKVRCSGLDKKAKYILLMDIIAADDCRYKFHNSRWMVAGKADPEM
Sbjct: 121 TEMVITKSGRRMFPPFKVRCSGLDKKAKYILLMDIIAADDCRYKFHNSRWMVAGKADPEM 180

Query: 181 PKRMYIHPDSPATGEQWMSKVVTFHKLKLTNNISDKHGFTLAFPSDHATWQGNYSFGTQT 240
           PKRMYIHPDSPATGEQWMSKVVTFHKLKLTNNISDKHGFTLAFPSDHATWQGNYSFGTQT
Sbjct: 181 PKRMYIHPDSPATGEQWMSKVVTFHKLKLTNNISDKHGFTLAFPSDHATWQGNYSFGTQT 240

Query: 241 ILNSMHKYQPRFHIVRANDILKLPYSTFRTYLFPETEFIAVTAYQNDKITQLKIDNNPFA 300
           ILNSMHKYQPRFHIVRANDILKLPYSTFRTYLFPETEFIAVTAYQNDKITQLKIDNNPFA
Sbjct: 241 ILNSMHKYQPRFHIVRANDILKLPYSTFRTYLFPETEFIAVTAYQNDKITQLKIDNNPFA 300

Query: 301 KGFRDTGNGRREKRKQLTLQSMRVFDERHKKENGTSDESSSEQAAFNCFAQASSPAASTV 360
           KGFRDTGNGRREKRKQLTLQSMRVFDERHKKENGTSDESSSEQAAFNCFAQASSPAASTV
Sbjct: 301 KGFRDTGNGRREKRKQLTLQSMRVFDERHKKENGTSDESSSEQAAFNCFAQASSPAASTV 360

Query: 361 GTSNLKDLCPSEGESDAEAESKEEHGPEACDAAKISTTTSEEPCRDKGSPAVKAHLFAAE 420
           GTSNLKDLCPSEGESDAEAESKEEHGPEACDAAKISTTTSEEPCRDKGSPAVKAHLFAAE
Sbjct: 361 GTSNLKDLCPSEGESDAEAESKEEHGPEACDAAKISTTTSEEPCRDKGSPAVKAHLFAAE 420

Query: 421 RPRDSGRLDKASPDSRHSPATISSSTRGLGAEERRSPVREGTAPAKVEEARALPGKEAFA 480
           RPRDSGRLDKASPDSRHSPATISSSTRGLGAEERRSPVREGTAPAKVEEARALPGKEAFA
Sbjct: 421 RPRDSGRLDKASPDSRHSPATISSSTRGLGAEERRSPVREGTAPAKVEEARALPGKEAFA 480

Query: 481 PLTVQTDAAAAHLAQGPLPGLGFAPGLAGQQFFNGHPLFLHPSQFAMGGAFSSMAAAGMG 540
           PLTVQTDAAAAHLAQGPLPGLGFAPGLAGQQFFNGHPLFLHPSQFAMGGAFSSMAAAGMG
Sbjct: 481 PLTVQTDAAAAHLAQGPLPGLGFAPGLAGQQFFNGHPLFLHPSQFAMGGAFSSMAAAGMG 540

Query: 541 PLLATVSGASTGVSGLDSTAMASAAAAQGLSGASAATLPFHLQQHVLASQGLAMSPFGSL 600
           PLLATVSGASTGVSGLDSTAMASAAAAQGLSGASAATLPFHLQQHVLASQGLAMSPFGSL
Sbjct: 541 PLLATVSGASTGVSGLDSTAMASAAAAQGLSGASAATLPFHLQQHVLASQGLAMSPFGSL 600

Query: 601 FPYPYTYMAAAAAASSAAASSSVHRHPFLNLNTMRPRLRYSPYSIPVPVPDGSSLLTTAL 660
           FPYPYTYMAAAAAASSAAASSSVHRHPFLNLNTMRPRLRYSPYSIPVPVPDGSSLLTTAL
Sbjct: 601 FPYPYTYMAAAAAASSAAASSSVHRHPFLNLNTMRPRLRYSPYSIPVPVPDGSSLLTTAL 660

Query: 661 PSMAAAAGPLDGKVAALAASPASVAVDSGSELNSRSSTLSSSSMSLSPKLCAEKEAATSE 720
           PSMAAAAGPLDGKVAALAASPASVAVDSGSELNSRSSTLSSSSMSLSPKLCAEKEAATSE
Sbjct: 661 PSMAAAAGPLDGKVAALAASPASVAVDSGSELNSRSSTLSSSSMSLSPKLCAEKEAATSE 720

Query: 721 LQSIQRLVSGLEAKPDRSRSASP 743
           LQSIQRLVSGLEAKPDRSRSASP
Sbjct: 721 LQSIQRLVSGLEAKPDRSRSASP 743


>gi|47419905 T-box 3 protein isoform 1 [Homo sapiens]
          Length = 723

 Score = 1425 bits (3688), Expect = 0.0
 Identities = 723/743 (97%), Positives = 723/743 (97%), Gaps = 20/743 (2%)

Query: 1   MSLSMRDPVIPGTSMAYHPFLPHRAPDFAMSAVLGHQPPFFPALTLPPNGAAALSLPGAL 60
           MSLSMRDPVIPGTSMAYHPFLPHRAPDFAMSAVLGHQPPFFPALTLPPNGAAALSLPGAL
Sbjct: 1   MSLSMRDPVIPGTSMAYHPFLPHRAPDFAMSAVLGHQPPFFPALTLPPNGAAALSLPGAL 60

Query: 61  AKPIMDQLVGAAETGIPFSSLGPQAHLRPLKTMEPEEEVEDDPKVHLEAKELWDQFHKRG 120
           AKPIMDQLVGAAETGIPFSSLGPQAHLRPLKTMEPEEEVEDDPKVHLEAKELWDQFHKRG
Sbjct: 61  AKPIMDQLVGAAETGIPFSSLGPQAHLRPLKTMEPEEEVEDDPKVHLEAKELWDQFHKRG 120

Query: 121 TEMVITKSGRRMFPPFKVRCSGLDKKAKYILLMDIIAADDCRYKFHNSRWMVAGKADPEM 180
           TEMVITKSGRRMFPPFKVRCSGLDKKAKYILLMDIIAADDCRYKFHNSRWMVAGKADPEM
Sbjct: 121 TEMVITKSGRRMFPPFKVRCSGLDKKAKYILLMDIIAADDCRYKFHNSRWMVAGKADPEM 180

Query: 181 PKRMYIHPDSPATGEQWMSKVVTFHKLKLTNNISDKHGFTLAFPSDHATWQGNYSFGTQT 240
           PKRMYIHPDSPATGEQWMSKVVTFHKLKLTNNISDKHGFT                    
Sbjct: 181 PKRMYIHPDSPATGEQWMSKVVTFHKLKLTNNISDKHGFT-------------------- 220

Query: 241 ILNSMHKYQPRFHIVRANDILKLPYSTFRTYLFPETEFIAVTAYQNDKITQLKIDNNPFA 300
           ILNSMHKYQPRFHIVRANDILKLPYSTFRTYLFPETEFIAVTAYQNDKITQLKIDNNPFA
Sbjct: 221 ILNSMHKYQPRFHIVRANDILKLPYSTFRTYLFPETEFIAVTAYQNDKITQLKIDNNPFA 280

Query: 301 KGFRDTGNGRREKRKQLTLQSMRVFDERHKKENGTSDESSSEQAAFNCFAQASSPAASTV 360
           KGFRDTGNGRREKRKQLTLQSMRVFDERHKKENGTSDESSSEQAAFNCFAQASSPAASTV
Sbjct: 281 KGFRDTGNGRREKRKQLTLQSMRVFDERHKKENGTSDESSSEQAAFNCFAQASSPAASTV 340

Query: 361 GTSNLKDLCPSEGESDAEAESKEEHGPEACDAAKISTTTSEEPCRDKGSPAVKAHLFAAE 420
           GTSNLKDLCPSEGESDAEAESKEEHGPEACDAAKISTTTSEEPCRDKGSPAVKAHLFAAE
Sbjct: 341 GTSNLKDLCPSEGESDAEAESKEEHGPEACDAAKISTTTSEEPCRDKGSPAVKAHLFAAE 400

Query: 421 RPRDSGRLDKASPDSRHSPATISSSTRGLGAEERRSPVREGTAPAKVEEARALPGKEAFA 480
           RPRDSGRLDKASPDSRHSPATISSSTRGLGAEERRSPVREGTAPAKVEEARALPGKEAFA
Sbjct: 401 RPRDSGRLDKASPDSRHSPATISSSTRGLGAEERRSPVREGTAPAKVEEARALPGKEAFA 460

Query: 481 PLTVQTDAAAAHLAQGPLPGLGFAPGLAGQQFFNGHPLFLHPSQFAMGGAFSSMAAAGMG 540
           PLTVQTDAAAAHLAQGPLPGLGFAPGLAGQQFFNGHPLFLHPSQFAMGGAFSSMAAAGMG
Sbjct: 461 PLTVQTDAAAAHLAQGPLPGLGFAPGLAGQQFFNGHPLFLHPSQFAMGGAFSSMAAAGMG 520

Query: 541 PLLATVSGASTGVSGLDSTAMASAAAAQGLSGASAATLPFHLQQHVLASQGLAMSPFGSL 600
           PLLATVSGASTGVSGLDSTAMASAAAAQGLSGASAATLPFHLQQHVLASQGLAMSPFGSL
Sbjct: 521 PLLATVSGASTGVSGLDSTAMASAAAAQGLSGASAATLPFHLQQHVLASQGLAMSPFGSL 580

Query: 601 FPYPYTYMAAAAAASSAAASSSVHRHPFLNLNTMRPRLRYSPYSIPVPVPDGSSLLTTAL 660
           FPYPYTYMAAAAAASSAAASSSVHRHPFLNLNTMRPRLRYSPYSIPVPVPDGSSLLTTAL
Sbjct: 581 FPYPYTYMAAAAAASSAAASSSVHRHPFLNLNTMRPRLRYSPYSIPVPVPDGSSLLTTAL 640

Query: 661 PSMAAAAGPLDGKVAALAASPASVAVDSGSELNSRSSTLSSSSMSLSPKLCAEKEAATSE 720
           PSMAAAAGPLDGKVAALAASPASVAVDSGSELNSRSSTLSSSSMSLSPKLCAEKEAATSE
Sbjct: 641 PSMAAAAGPLDGKVAALAASPASVAVDSGSELNSRSSTLSSSSMSLSPKLCAEKEAATSE 700

Query: 721 LQSIQRLVSGLEAKPDRSRSASP 743
           LQSIQRLVSGLEAKPDRSRSASP
Sbjct: 701 LQSIQRLVSGLEAKPDRSRSASP 723


>gi|197333868 T-box 2 [Homo sapiens]
          Length = 712

 Score =  675 bits (1741), Expect = 0.0
 Identities = 425/781 (54%), Positives = 488/781 (62%), Gaps = 117/781 (14%)

Query: 5   MRDPVIPGTSMAYHPFLPHRAPDFAMSAVLGH-QPPFFPALTLPPNGAAALSLPGALAKP 63
           MR+P +  ++MAYHPF   R  DF MSA L   QP FFPAL LPP         GALAKP
Sbjct: 1   MREPALAASAMAYHPFHAPRPADFPMSAFLAAAQPSFFPALALPP---------GALAKP 51

Query: 64  IMDQ-----------LVGAAETGIPFSSLGPQ---AHLRPLKTMEPEEEVEDDPKVHLEA 109
           + D               AAE G+  S+LGP    AHLR LK++EPE+EVEDDPKV LEA
Sbjct: 52  LPDPGLAGAAAAAAAAAAAAEAGLHVSALGPHPPAAHLRSLKSLEPEDEVEDDPKVTLEA 111

Query: 110 KELWDQFHKRGTEMVITKSGRRMFPPFKVRCSGLDKKAKYILLMDIIAADDCRYKFHNSR 169
           KELWDQFHK GTEMVITKSGRRMFPPFKVR SGLDKKAKYILLMDI+AADDCRYKFHNSR
Sbjct: 112 KELWDQFHKLGTEMVITKSGRRMFPPFKVRVSGLDKKAKYILLMDIVAADDCRYKFHNSR 171

Query: 170 WMVAGKADPEMPKRMYIHPDSPATGEQWMSKVVTFHKLKLTNNISDKHGFTLAFPSDHAT 229
           WMVAGKADPEMPKRMYIHPDSPATGEQWM+K V FHKLKLTNNISDKHGF          
Sbjct: 172 WMVAGKADPEMPKRMYIHPDSPATGEQWMAKPVAFHKLKLTNNISDKHGF---------- 221

Query: 230 WQGNYSFGTQTILNSMHKYQPRFHIVRANDILKLPYSTFRTYLFPETEFIAVTAYQNDKI 289
                     TILNSMHKYQPRFHIVRANDILKLPYSTFRTY+FPET+FIAVTAYQNDKI
Sbjct: 222 ----------TILNSMHKYQPRFHIVRANDILKLPYSTFRTYVFPETDFIAVTAYQNDKI 271

Query: 290 TQLKIDNNPFAKGFRDTGNGRREKRKQLTLQSMRVFDERHKKENGTSDESSSEQAAFNCF 349
           TQLKIDNNPFAKGFRDTGNGRREKRKQLTL S+R+++E  K E    D + S+ ++ +  
Sbjct: 272 TQLKIDNNPFAKGFRDTGNGRREKRKQLTLPSLRLYEEHCKPER---DGAESDASSCDPP 328

Query: 350 AQASSPAASTVGTSNLKDLCPSEGESDAEAESKEEHGPEACDAAKISTTTSEEPCRDKGS 409
                P +     S L+       E    A+S  E  PE     +        P  D  S
Sbjct: 329 PAREPPTSPGAAPSPLRLHRARAEEKSCAADSDPE--PERLSEERAGAPLGRSPAPDSAS 386

Query: 410 PAVKAHLFAAERPRDSGRLDKASPDSRHSPATISSSTRGLGAEERRSPVREGTAPAKVEE 469
           P     L   ER R     ++ SP+    PA     + G G    RS  +E     + +E
Sbjct: 387 P---TRLTEPERAR-----ERRSPERGKEPA----ESGGDGPFGLRSLEKERAEARRKDE 434

Query: 470 AR--ALPGKE-AFAPLTVQTDAAAAHLAQGPLPGLGFAPGLAGQQFFN----GHPLFLHP 522
            R  A  GKE   APL VQTD+A+  L  G LPGL F+  L GQQFF     G PLFLHP
Sbjct: 435 GRKEAAEGKEQGLAPLVVQTDSASP-LGAGHLPGLAFSSHLHGQQFFGPLGAGQPLFLHP 493

Query: 523 SQFAMG-GAFSSMAAAGMGPLLATVSGASTG-------VSGLDSTAMASAAAAQGLSGAS 574
            QF MG GAFS+M   GMG LLA+V+G   G        +GLD+  +  AA+A     ++
Sbjct: 494 GQFTMGPGAFSAM---GMGHLLASVAGGGNGGGGGPGTAAGLDAGGLGPAASA----AST 546

Query: 575 AATLPFHLQQHVLASQGLAMSPFGSLFPYPYTYMAAAAAASS-----------AAASSSV 623
           AA  PFHL QH+LASQG+ M  FG LFPYPYTYMAAAAAA+S           AAA+ S+
Sbjct: 547 AAPFPFHLSQHMLASQGIPMPTFGGLFPYPYTYMAAAAAAASALPATSAAAAAAAAAGSL 606

Query: 624 HRHPFLNLNTMRPRLRYSPYSIPVPVPDGSSLLTTALPSMAA-AAGPLDGKVAALAASPA 682
            R PF  L + RPRLR+SPY IPV +P  +SLLTT L S  + AAG    + + L     
Sbjct: 607 SRSPF--LGSARPRLRFSPYQIPVTIPPSTSLLTTGLASEGSKAAGGNSREPSPL----- 659

Query: 683 SVAVDSGSELNSRSSTLSSSSMSLSPKLCAEKEAATSELQSIQRLVSGLEAKPDRSRSAS 742
                   EL  R     S   +LSP   A KEAA +ELQSIQRLVSGLE++    R+ S
Sbjct: 660 -------PELALRKVGAPSRG-ALSPSGSA-KEAA-NELQSIQRLVSGLESQ----RALS 705

Query: 743 P 743
           P
Sbjct: 706 P 706


>gi|18201894 T-box 5 isoform 3 [Homo sapiens]
          Length = 468

 Score =  239 bits (611), Expect = 5e-63
 Identities = 162/444 (36%), Positives = 223/444 (50%), Gaps = 57/444 (12%)

Query: 104 KVHLEAKELWDQFHKRGTEMVITKSGRRMFPPFKVRCSGLDKKAKYILLMDIIAADDCRY 163
           KV L  +ELW +FH+ GTEM+ITK+GRRMFP +KV+ +GL+ K KYILLMDI+ ADD RY
Sbjct: 5   KVFLHERELWLKFHEVGTEMIITKAGRRMFPSYKVKVTGLNPKTKYILLMDIVPADDHRY 64

Query: 164 KFHNSRWMVAGKADPEMPKRMYIHPDSPATGEQWMSKVVTFHKLKLTNNISDKHGFTLAF 223
           KF +++W V GKA+P MP R+Y+HPDSPATG  WM ++V+F KLKLTNN  D  G     
Sbjct: 65  KFADNKWSVTGKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDPFG----- 119

Query: 224 PSDHATWQGNYSFGTQTILNSMHKYQPRFHIVRA--NDILKLPYSTFRTYLFPETEFIAV 281
                            ILNSMHKYQPR HIV+A  N+      + F T++FPET FIAV
Sbjct: 120 ---------------HIILNSMHKYQPRLHIVKADENNGFGSKNTAFCTHVFPETAFIAV 164

Query: 282 TAYQNDKITQLKIDNNPFAKGFRDTGNGRREKRKQLTLQSMRVFDERHKKENGTSDES-- 339
           T+YQN KITQLKI+NNPFAKGFR + +    +  ++  +   V      ++   S+ S  
Sbjct: 165 TSYQNHKITQLKIENNPFAKGFRGSDDMELHRMSRMQSKEYPVVPRSTVRQKVASNHSPF 224

Query: 340 SSEQAAFNCFAQASSPAASTVGTSN-LKDLCPSEGESDAEAESKEEHGPEACDAAKISTT 398
           SSE  A +  +   S      G S   +DL P         E  + +        + STT
Sbjct: 225 SSESRALSTSSNLGSQYQCENGVSGPSQDLLPPPNPYPLPQEHSQIYHCTKRKEEECSTT 284

Query: 399 TSEEPCRD---KGSPAVKAHLFAAERPRDSGRLDKASPDSRHSPATISSSTRGLGAEERR 455
             + P +    + SP+ +   + +  P+  G       +S    A + +S+         
Sbjct: 285 --DHPYKKPYMETSPSEEDSFYRSSYPQQQGLGASYRTESAQRQACMYASS--------- 333

Query: 456 SPVREGTAPAKVEEARALPGKEAFAPLTVQT---------DAAAAHLAQGPLPGLGFAPG 506
           +P  E     +       P   +++  TV T            +AH   GPL      P 
Sbjct: 334 APPSEPVPSLEDISCNTWPSMPSYSSCTVTTVQPMDRLPYQHFSAHFTSGPL-----VPR 388

Query: 507 LAGQQFFN----GHPLFLHPSQFA 526
           LAG         G  +F H +  A
Sbjct: 389 LAGMANHGSPQLGEGMFQHQTSVA 412


>gi|18201892 T-box 5 isoform 1 [Homo sapiens]
          Length = 518

 Score =  239 bits (611), Expect = 5e-63
 Identities = 162/444 (36%), Positives = 223/444 (50%), Gaps = 57/444 (12%)

Query: 104 KVHLEAKELWDQFHKRGTEMVITKSGRRMFPPFKVRCSGLDKKAKYILLMDIIAADDCRY 163
           KV L  +ELW +FH+ GTEM+ITK+GRRMFP +KV+ +GL+ K KYILLMDI+ ADD RY
Sbjct: 55  KVFLHERELWLKFHEVGTEMIITKAGRRMFPSYKVKVTGLNPKTKYILLMDIVPADDHRY 114

Query: 164 KFHNSRWMVAGKADPEMPKRMYIHPDSPATGEQWMSKVVTFHKLKLTNNISDKHGFTLAF 223
           KF +++W V GKA+P MP R+Y+HPDSPATG  WM ++V+F KLKLTNN  D  G     
Sbjct: 115 KFADNKWSVTGKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDPFG----- 169

Query: 224 PSDHATWQGNYSFGTQTILNSMHKYQPRFHIVRA--NDILKLPYSTFRTYLFPETEFIAV 281
                            ILNSMHKYQPR HIV+A  N+      + F T++FPET FIAV
Sbjct: 170 ---------------HIILNSMHKYQPRLHIVKADENNGFGSKNTAFCTHVFPETAFIAV 214

Query: 282 TAYQNDKITQLKIDNNPFAKGFRDTGNGRREKRKQLTLQSMRVFDERHKKENGTSDES-- 339
           T+YQN KITQLKI+NNPFAKGFR + +    +  ++  +   V      ++   S+ S  
Sbjct: 215 TSYQNHKITQLKIENNPFAKGFRGSDDMELHRMSRMQSKEYPVVPRSTVRQKVASNHSPF 274

Query: 340 SSEQAAFNCFAQASSPAASTVGTSN-LKDLCPSEGESDAEAESKEEHGPEACDAAKISTT 398
           SSE  A +  +   S      G S   +DL P         E  + +        + STT
Sbjct: 275 SSESRALSTSSNLGSQYQCENGVSGPSQDLLPPPNPYPLPQEHSQIYHCTKRKEEECSTT 334

Query: 399 TSEEPCRD---KGSPAVKAHLFAAERPRDSGRLDKASPDSRHSPATISSSTRGLGAEERR 455
             + P +    + SP+ +   + +  P+  G       +S    A + +S+         
Sbjct: 335 --DHPYKKPYMETSPSEEDSFYRSSYPQQQGLGASYRTESAQRQACMYASS--------- 383

Query: 456 SPVREGTAPAKVEEARALPGKEAFAPLTVQT---------DAAAAHLAQGPLPGLGFAPG 506
           +P  E     +       P   +++  TV T            +AH   GPL      P 
Sbjct: 384 APPSEPVPSLEDISCNTWPSMPSYSSCTVTTVQPMDRLPYQHFSAHFTSGPL-----VPR 438

Query: 507 LAGQQFFN----GHPLFLHPSQFA 526
           LAG         G  +F H +  A
Sbjct: 439 LAGMANHGSPQLGEGMFQHQTSVA 462


>gi|31652232 T-box 5 isoform 1 [Homo sapiens]
          Length = 518

 Score =  239 bits (611), Expect = 5e-63
 Identities = 162/444 (36%), Positives = 223/444 (50%), Gaps = 57/444 (12%)

Query: 104 KVHLEAKELWDQFHKRGTEMVITKSGRRMFPPFKVRCSGLDKKAKYILLMDIIAADDCRY 163
           KV L  +ELW +FH+ GTEM+ITK+GRRMFP +KV+ +GL+ K KYILLMDI+ ADD RY
Sbjct: 55  KVFLHERELWLKFHEVGTEMIITKAGRRMFPSYKVKVTGLNPKTKYILLMDIVPADDHRY 114

Query: 164 KFHNSRWMVAGKADPEMPKRMYIHPDSPATGEQWMSKVVTFHKLKLTNNISDKHGFTLAF 223
           KF +++W V GKA+P MP R+Y+HPDSPATG  WM ++V+F KLKLTNN  D  G     
Sbjct: 115 KFADNKWSVTGKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDPFG----- 169

Query: 224 PSDHATWQGNYSFGTQTILNSMHKYQPRFHIVRA--NDILKLPYSTFRTYLFPETEFIAV 281
                            ILNSMHKYQPR HIV+A  N+      + F T++FPET FIAV
Sbjct: 170 ---------------HIILNSMHKYQPRLHIVKADENNGFGSKNTAFCTHVFPETAFIAV 214

Query: 282 TAYQNDKITQLKIDNNPFAKGFRDTGNGRREKRKQLTLQSMRVFDERHKKENGTSDES-- 339
           T+YQN KITQLKI+NNPFAKGFR + +    +  ++  +   V      ++   S+ S  
Sbjct: 215 TSYQNHKITQLKIENNPFAKGFRGSDDMELHRMSRMQSKEYPVVPRSTVRQKVASNHSPF 274

Query: 340 SSEQAAFNCFAQASSPAASTVGTSN-LKDLCPSEGESDAEAESKEEHGPEACDAAKISTT 398
           SSE  A +  +   S      G S   +DL P         E  + +        + STT
Sbjct: 275 SSESRALSTSSNLGSQYQCENGVSGPSQDLLPPPNPYPLPQEHSQIYHCTKRKEEECSTT 334

Query: 399 TSEEPCRD---KGSPAVKAHLFAAERPRDSGRLDKASPDSRHSPATISSSTRGLGAEERR 455
             + P +    + SP+ +   + +  P+  G       +S    A + +S+         
Sbjct: 335 --DHPYKKPYMETSPSEEDSFYRSSYPQQQGLGASYRTESAQRQACMYASS--------- 383

Query: 456 SPVREGTAPAKVEEARALPGKEAFAPLTVQT---------DAAAAHLAQGPLPGLGFAPG 506
           +P  E     +       P   +++  TV T            +AH   GPL      P 
Sbjct: 384 APPSEPVPSLEDISCNTWPSMPSYSSCTVTTVQPMDRLPYQHFSAHFTSGPL-----VPR 438

Query: 507 LAGQQFFN----GHPLFLHPSQFA 526
           LAG         G  +F H +  A
Sbjct: 439 LAGMANHGSPQLGEGMFQHQTSVA 462


>gi|18129690 T-box 4 [Homo sapiens]
          Length = 545

 Score =  238 bits (608), Expect = 1e-62
 Identities = 119/210 (56%), Positives = 150/210 (71%), Gaps = 22/210 (10%)

Query: 97  EEVEDDPKVHLEAKELWDQFHKRGTEMVITKSGRRMFPPFKVRCSGLDKKAKYILLMDII 156
           E+  ++ KV L  KELW +FH+ GTEM+ITK+GRRMFP +KV+ +G++ K KYILL+DI+
Sbjct: 61  EQTIENIKVGLHEKELWKKFHEAGTEMIITKAGRRMFPSYKVKVTGMNPKTKYILLIDIV 120

Query: 157 AADDCRYKFHNSRWMVAGKADPEMPKRMYIHPDSPATGEQWMSKVVTFHKLKLTNNISDK 216
            ADD RYKF +++WMVAGKA+P MP R+Y+HPDSPATG  WM ++V+F KLKLTNN  D 
Sbjct: 121 PADDHRYKFCDNKWMVAGKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDP 180

Query: 217 HGFTLAFPSDHATWQGNYSFGTQTILNSMHKYQPRFHIVRA--NDILKLPYSTFRTYLFP 274
            G                      ILNSMHKYQPR HIV+A  N+      + F T++FP
Sbjct: 181 FG--------------------HIILNSMHKYQPRLHIVKADENNAFGSKNTAFCTHVFP 220

Query: 275 ETEFIAVTAYQNDKITQLKIDNNPFAKGFR 304
           ET FI+VT+YQN KITQLKI+NNPFAKGFR
Sbjct: 221 ETSFISVTSYQNHKITQLKIENNPFAKGFR 250


>gi|18201896 T-box 5 isoform 2 [Homo sapiens]
          Length = 349

 Score =  236 bits (603), Expect = 4e-62
 Identities = 131/272 (48%), Positives = 169/272 (62%), Gaps = 25/272 (9%)

Query: 104 KVHLEAKELWDQFHKRGTEMVITKSGRRMFPPFKVRCSGLDKKAKYILLMDIIAADDCRY 163
           KV L  +ELW +FH+ GTEM+ITK+GRRMFP +KV+ +GL+ K KYILLMDI+ ADD RY
Sbjct: 55  KVFLHERELWLKFHEVGTEMIITKAGRRMFPSYKVKVTGLNPKTKYILLMDIVPADDHRY 114

Query: 164 KFHNSRWMVAGKADPEMPKRMYIHPDSPATGEQWMSKVVTFHKLKLTNNISDKHGFTLAF 223
           KF +++W V GKA+P MP R+Y+HPDSPATG  WM ++V+F KLKLTNN  D  G     
Sbjct: 115 KFADNKWSVTGKAEPAMPGRLYVHPDSPATGAHWMRQLVSFQKLKLTNNHLDPFG----- 169

Query: 224 PSDHATWQGNYSFGTQTILNSMHKYQPRFHIVRA--NDILKLPYSTFRTYLFPETEFIAV 281
                            ILNSMHKYQPR HIV+A  N+      + F T++FPET FIAV
Sbjct: 170 ---------------HIILNSMHKYQPRLHIVKADENNGFGSKNTAFCTHVFPETAFIAV 214

Query: 282 TAYQNDKITQLKIDNNPFAKGFRDTGNGRREKRKQLTLQSMRVFDERHKKENGTSDES-- 339
           T+YQN KITQLKI+NNPFAKGFR + +    +  ++  +   V      ++   S+ S  
Sbjct: 215 TSYQNHKITQLKIENNPFAKGFRGSDDMELHRMSRMQSKEYPVVPRSTVRQKVASNHSPF 274

Query: 340 SSEQAAFNCFAQASSPAASTVGTSN-LKDLCP 370
           SSE  A +  +   S      G S   +DL P
Sbjct: 275 SSESRALSTSSNLGSQYQCENGVSGPSQDLLP 306


>gi|117676399 T-box transcription factor TBX20 [Homo sapiens]
          Length = 447

 Score =  236 bits (602), Expect = 6e-62
 Identities = 142/340 (41%), Positives = 190/340 (55%), Gaps = 35/340 (10%)

Query: 70  GAAETGIPFSSLGPQAHLRPLKTMEPEEEVEDDPKVHLEAKELWDQFHKRGTEMVITKSG 129
           G      P SS      L P   + P EE+       LE KELWD+FH+ GTEM+ITKSG
Sbjct: 68  GGGSGSSPSSSSLCTEPLIPTTPIIPSEEMAKIA-CSLETKELWDKFHELGTEMIITKSG 126

Query: 130 RRMFPPFKVRCSGLDKKAKYILLMDIIAADDCRYK--FHNSRWMVAGKADPEMPKRMYIH 187
           RRMFP  +V  SG+D +AKYI+LMDI+  D+ RY+  +H S W+VAGKADP +P R+Y+H
Sbjct: 127 RRMFPTIRVSFSGVDPEAKYIVLMDIVPVDNKRYRYAYHRSSWLVAGKADPPLPARLYVH 186

Query: 188 PDSPATGEQWMSKVVTFHKLKLTNNISDKHGFTLAFPSDHATWQGNYSFGTQTILNSMHK 247
           PDSP TGEQ + ++V+F K+KLTNN  D+HG                      ILNSMHK
Sbjct: 187 PDSPFTGEQLLKQMVSFEKVKLTNNELDQHG--------------------HIILNSMHK 226

Query: 248 YQPRFHIVRAND----ILKLPYSTFRTYLFPETEFIAVTAYQNDKITQLKIDNNPFAKGF 303
           YQPR HI++  D    +L L    FRT++FPET F AVTAYQN  IT+LKID+NPFAKGF
Sbjct: 227 YQPRVHIIKKKDHTASLLNLKSEEFRTFIFPETVFTAVTAYQNQLITKLKIDSNPFAKGF 286

Query: 304 RDTGNGRREKRKQLTLQSMRVFDERHKKENGTSDESSSEQAAFNCFAQASSPAASTVGTS 363
           RD+      +   +  +S+    ++H            E+      +Q +    S   TS
Sbjct: 287 RDS-----SRLTDIERESVESLIQKHSYARSPIRTYGGEEDVLGDESQTTPNRGSAFTTS 341

Query: 364 NLKDLCPSEGESDAEAESKEEHGPEACDAAKISTTTSEEP 403
           +  +L  S   S + +    +H P++  A   ST +   P
Sbjct: 342 D--NLSLSSWVSSSSSFPGFQH-PQSLTALGTSTASIATP 378


>gi|5174711 T-box 1 isoform B [Homo sapiens]
          Length = 372

 Score =  221 bits (562), Expect = 2e-57
 Identities = 111/206 (53%), Positives = 140/206 (67%), Gaps = 25/206 (12%)

Query: 105 VHLEAKELWDQFHKRGTEMVITKSGRRMFPPFKVRCSGLDKKAKYILLMDIIAADDCRYK 164
           V LE K LWD+F++ GTEM++TK+GRRMFP F+V+  G+D  A Y+LLMD +  DD RY+
Sbjct: 112 VQLEMKALWDEFNQLGTEMIVTKAGRRMFPTFQVKLFGMDPMADYMLLMDFVPVDDKRYR 171

Query: 165 --FHNSRWMVAGKADPEMPKRMYIHPDSPATGEQWMSKVVTFHKLKLTNNISDKHGFTLA 222
             FH+S W+VAGKADP  P R++ HPDSPA G QWM ++V+F KLKLTNN+ D +G    
Sbjct: 172 YAFHSSSWLVAGKADPATPGRVHYHPDSPAKGAQWMKQIVSFDKLKLTNNLLDDNG---- 227

Query: 223 FPSDHATWQGNYSFGTQTILNSMHKYQPRFHIVRAN---DILKLPYSTFRTYLFPETEFI 279
                             ILNSMH+YQPRFH+V  +   D  K     F+T++F ET F 
Sbjct: 228 ----------------HIILNSMHRYQPRFHVVYVDPRKDSEKYAEENFKTFVFEETRFT 271

Query: 280 AVTAYQNDKITQLKIDNNPFAKGFRD 305
           AVTAYQN +ITQLKI +NPFAKGFRD
Sbjct: 272 AVTAYQNHRITQLKIASNPFAKGFRD 297


>gi|18104952 T-box 1 isoform C [Homo sapiens]
          Length = 495

 Score =  221 bits (562), Expect = 2e-57
 Identities = 111/206 (53%), Positives = 140/206 (67%), Gaps = 25/206 (12%)

Query: 105 VHLEAKELWDQFHKRGTEMVITKSGRRMFPPFKVRCSGLDKKAKYILLMDIIAADDCRYK 164
           V LE K LWD+F++ GTEM++TK+GRRMFP F+V+  G+D  A Y+LLMD +  DD RY+
Sbjct: 112 VQLEMKALWDEFNQLGTEMIVTKAGRRMFPTFQVKLFGMDPMADYMLLMDFVPVDDKRYR 171

Query: 165 --FHNSRWMVAGKADPEMPKRMYIHPDSPATGEQWMSKVVTFHKLKLTNNISDKHGFTLA 222
             FH+S W+VAGKADP  P R++ HPDSPA G QWM ++V+F KLKLTNN+ D +G    
Sbjct: 172 YAFHSSSWLVAGKADPATPGRVHYHPDSPAKGAQWMKQIVSFDKLKLTNNLLDDNG---- 227

Query: 223 FPSDHATWQGNYSFGTQTILNSMHKYQPRFHIVRAN---DILKLPYSTFRTYLFPETEFI 279
                             ILNSMH+YQPRFH+V  +   D  K     F+T++F ET F 
Sbjct: 228 ----------------HIILNSMHRYQPRFHVVYVDPRKDSEKYAEENFKTFVFEETRFT 271

Query: 280 AVTAYQNDKITQLKIDNNPFAKGFRD 305
           AVTAYQN +ITQLKI +NPFAKGFRD
Sbjct: 272 AVTAYQNHRITQLKIASNPFAKGFRD 297


>gi|18104950 T-box 1 isoform A [Homo sapiens]
          Length = 398

 Score =  221 bits (562), Expect = 2e-57
 Identities = 111/206 (53%), Positives = 140/206 (67%), Gaps = 25/206 (12%)

Query: 105 VHLEAKELWDQFHKRGTEMVITKSGRRMFPPFKVRCSGLDKKAKYILLMDIIAADDCRYK 164
           V LE K LWD+F++ GTEM++TK+GRRMFP F+V+  G+D  A Y+LLMD +  DD RY+
Sbjct: 112 VQLEMKALWDEFNQLGTEMIVTKAGRRMFPTFQVKLFGMDPMADYMLLMDFVPVDDKRYR 171

Query: 165 --FHNSRWMVAGKADPEMPKRMYIHPDSPATGEQWMSKVVTFHKLKLTNNISDKHGFTLA 222
             FH+S W+VAGKADP  P R++ HPDSPA G QWM ++V+F KLKLTNN+ D +G    
Sbjct: 172 YAFHSSSWLVAGKADPATPGRVHYHPDSPAKGAQWMKQIVSFDKLKLTNNLLDDNG---- 227

Query: 223 FPSDHATWQGNYSFGTQTILNSMHKYQPRFHIVRAN---DILKLPYSTFRTYLFPETEFI 279
                             ILNSMH+YQPRFH+V  +   D  K     F+T++F ET F 
Sbjct: 228 ----------------HIILNSMHRYQPRFHVVYVDPRKDSEKYAEENFKTFVFEETRFT 271

Query: 280 AVTAYQNDKITQLKIDNNPFAKGFRD 305
           AVTAYQN +ITQLKI +NPFAKGFRD
Sbjct: 272 AVTAYQNHRITQLKIASNPFAKGFRD 297


>gi|32567784 T-box 10 [Homo sapiens]
          Length = 385

 Score =  220 bits (561), Expect = 3e-57
 Identities = 116/233 (49%), Positives = 150/233 (64%), Gaps = 26/233 (11%)

Query: 79  SSLGPQAHLRPLKTMEPEEEVEDDPKVHLEAKELWDQFHKRGTEMVITKSGRRMFPPFKV 138
           SS G QA   P     P+        V LE K LW++F++ GTEM++TK+GRRMFPPF+V
Sbjct: 42  SSTGAQAVAEPTG-QGPKNPRVSRVTVQLEMKPLWEEFNQLGTEMIVTKAGRRMFPPFQV 100

Query: 139 RCSGLDKKAKYILLMDIIAADDCRYK--FHNSRWMVAGKADPEMPKRMYIHPDSPATGEQ 196
           +  G+D  A Y LLMD I  DD RY+  FH+S W+VAGKADP  P R++ HPDSPA G Q
Sbjct: 101 KILGMDSLADYALLMDFIPLDDKRYRYAFHSSAWLVAGKADPATPGRVHFHPDSPAKGAQ 160

Query: 197 WMSKVVTFHKLKLTNNISDKHGFTLAFPSDHATWQGNYSFGTQTILNSMHKYQPRFHIVR 256
           WM ++V+F KLKLTNN+ D +G                      ILNSMH+YQPRFH+V 
Sbjct: 161 WMRQIVSFDKLKLTNNLLDDNG--------------------HIILNSMHRYQPRFHVVF 200

Query: 257 AN---DILKLPYSTFRTYLFPETEFIAVTAYQNDKITQLKIDNNPFAKGFRDT 306
            +   D  +     F++++F ET+F AVTAYQN +ITQLKI +NPFAKGFR++
Sbjct: 201 VDPRKDSERYAQENFKSFIFTETQFTAVTAYQNHRITQLKIASNPFAKGFRES 253


>gi|18201900 T-box 6 [Homo sapiens]
          Length = 436

 Score =  218 bits (554), Expect = 2e-56
 Identities = 118/273 (43%), Positives = 165/273 (60%), Gaps = 34/273 (12%)

Query: 107 LEAKELWDQFHKRGTEMVITKSGRRMFPPFKVRCSGLDKKAKYILLMDIIAADDCRYKFH 166
           LE +ELW +F   GTEM+ITK+GRRMFP  +V  +GLD +A+Y+ L+D+I  D  RY++ 
Sbjct: 95  LENRELWKEFSSVGTEMIITKAGRRMFPACRVSVTGLDPEARYLFLLDVIPVDGARYRWQ 154

Query: 167 NSRWMVAGKADPEMPKRMYIHPDSPATGEQWMSKVVTFHKLKLTNNISDKHGFTLAFPSD 226
             RW  +GKA+P +P R+YIHPDSPATG  WM + V+FH++KLTN+  D HG        
Sbjct: 155 GRRWEPSGKAEPRLPDRVYIHPDSPATGAHWMRQPVSFHRVKLTNSTLDPHG-------- 206

Query: 227 HATWQGNYSFGTQTILNSMHKYQPRFHIVRANDILKLPYSTFRTYLFPETEFIAVTAYQN 286
                         IL+SMHKYQPR H+VRA  +    +    ++ FPET FI+VTAYQN
Sbjct: 207 ------------HLILHSMHKYQPRIHLVRAAQLCSQHWGGMASFRFPETTFISVTAYQN 254

Query: 287 DKITQLKIDNNPFAKGFRDTGNGRREKRKQLTLQSMRVFDERHKKENGTSDESSSEQAAF 346
            +ITQLKI  NPFAKGFR+  NGR  KR++         D R K++    + +++E  A+
Sbjct: 255 PQITQLKIAANPFAKGFRE--NGRNCKRER---------DARVKRKLRGPEPAATE--AY 301

Query: 347 NCFAQASSPAASTVGTSNLKDLCPSEGESDAEA 379
                   P  ST+G  ++++  P +  +  EA
Sbjct: 302 GSGDTPGGPCDSTLG-GDIRESDPEQAPAPGEA 333


>gi|122937456 T-box 18 [Homo sapiens]
          Length = 607

 Score =  213 bits (543), Expect = 4e-55
 Identities = 124/282 (43%), Positives = 162/282 (57%), Gaps = 38/282 (13%)

Query: 46  LPPNGAAALSLPGALAKPIMDQLVGAAETGI-----PFSSLGPQAHLRPLKTM-EPEEEV 99
           LPP  A A S P      +     G  E G      P +S G      P +++  P   +
Sbjct: 75  LPPP-AGATSGPARSGADLERGAAGGCEDGFQQGASPLASPGGSPKGSPARSLARPGTPL 133

Query: 100 EDD--PKVHLEAKELWDQFHKRGTEMVITKSGRRMFPPFKVRCSGLDKKAKYILLMDIIA 157
                P+V L+  ELW +FH+ GTEM+ITK+GRRMFP  +V+ SGLD   +Y + MDI+ 
Sbjct: 134 PSPQAPRVDLQGAELWKRFHEIGTEMIITKAGRRMFPAMRVKISGLDPHQQYYIAMDIVP 193

Query: 158 ADDCRYKF--HNSRWMVAGKADPEMPKRMYIHPDSPATGEQWMSKVVTFHKLKLTNNISD 215
            D+ RY++  H+S+WMVAG AD  +P R+YIHPDSPA+GE WM +V++F KLKLTNN  D
Sbjct: 194 VDNKRYRYVYHSSKWMVAGNADSPVPPRVYIHPDSPASGETWMRQVISFDKLKLTNNELD 253

Query: 216 KHGFTLAFPSDHATWQGNYSFGTQTILNSMHKYQPRFHIVR------ANDILKLPYST-F 268
             G                      IL+SMHKYQPR H++R       + I  +P     
Sbjct: 254 DQG--------------------HIILHSMHKYQPRVHVIRKDCGDDLSPIKPVPSGEGV 293

Query: 269 RTYLFPETEFIAVTAYQNDKITQLKIDNNPFAKGFRDTGNGR 310
           + + FPET F  VTAYQN +IT+LKID NPFAKGFRD+G  R
Sbjct: 294 KAFSFPETVFTTVTAYQNQQITRLKIDRNPFAKGFRDSGRNR 335


>gi|55770860 T-box 15 [Homo sapiens]
          Length = 496

 Score =  206 bits (524), Expect = 6e-53
 Identities = 113/263 (42%), Positives = 153/263 (58%), Gaps = 42/263 (15%)

Query: 101 DDPKVHLEAKELWDQFHKRGTEMVITKSGRRMFPPFKVRCSGLDKKAKYILLMDIIAADD 160
           ++ +V L+  +LW +FH  GTEM+ITK+GRRMFP  +V+ +GLD   +Y + MDI+  D+
Sbjct: 5   EEIQVELQCADLWKRFHDIGTEMIITKAGRRMFPAMRVKITGLDPHQQYYIAMDIVPVDN 64

Query: 161 CRYKF--HNSRWMVAGKADPEMPKRMYIHPDSPATGEQWMSKVVTFHKLKLTNNISDKHG 218
            RY++  H+S+WMVAG AD  +P R+YIHPDS A+G+ WM +VV+F KLKLTNN  D  G
Sbjct: 65  KRYRYVYHSSKWMVAGNADSPVPPRVYIHPDSLASGDTWMRQVVSFDKLKLTNNELDDQG 124

Query: 219 FTLAFPSDHATWQGNYSFGTQTILNSMHKYQPRFHIVRANDILKLPYST-------FRTY 271
                                 IL+SMHKYQPR H++R +    L  +         +T+
Sbjct: 125 --------------------HIILHSMHKYQPRVHVIRKDFSSDLSPTKPVPVGDGVKTF 164

Query: 272 LFPETEFIAVTAYQNDKITQLKIDNNPFAKGFRDTGNGR-------------REKRKQLT 318
            FPET F  VTAYQN +IT+LKID NPFAKGFRD+G  R             R   + LT
Sbjct: 165 NFPETVFTTVTAYQNQQITRLKIDRNPFAKGFRDSGRNRTGLEAIMETYAFWRPPVRTLT 224

Query: 319 LQSMRVFDERHKKENGTSDESSS 341
            +      ++     GTS  +SS
Sbjct: 225 FEDFTTMQKQQGGSTGTSPTTSS 247


>gi|122937388 MAX gene associated [Homo sapiens]
          Length = 3114

 Score =  197 bits (500), Expect = 4e-50
 Identities = 117/285 (41%), Positives = 156/285 (54%), Gaps = 35/285 (12%)

Query: 33  VLGHQPPFFPALTLPPNGAAALSLPGALAKPIMDQLVGAAETGIPFSSLGPQAHLRPLKT 92
           V G  P FF  L  P NG       G L     D    A+    P  S G        K 
Sbjct: 17  VAGAAPTFFVILKQPGNGKTD---QGILVTN-QDACALASSVSSPVKSKG--------KI 64

Query: 93  MEPEEEVEDDPKVHLEAKELWDQFHKRGTEMVITKSGRRMFPPFKVRCSGLDKKAKYILL 152
             P +       V L+   +W++F+ R TEM++TK GRRMFP  +   +GLD   KYIL+
Sbjct: 65  CLPADCTVGGITVTLDNNSMWNEFYHRSTEMILTKQGRRMFPYCRYWITGLDSNLKYILV 124

Query: 153 MDIIAADDCRYKFHNSRWMVAGKADPEMPKRMYIHPDSPATGEQWMSKVVTFHKLKLTNN 212
           MDI   D+ RYK++   W  +GKA+P +  R++IHP+SP+TG  WM + V+F+KLKLTNN
Sbjct: 125 MDISPVDNHRYKWNGRWWEPSGKAEPHVLGRVFIHPESPSTGHYWMHQPVSFYKLKLTNN 184

Query: 213 ISDKHGFTLAFPSDHATWQGNYSFGTQTILNSMHKYQPRFHIV---RANDILKLPYSTFR 269
             D+ G                      IL+SMH+Y PR H+V   +A ++++L      
Sbjct: 185 TLDQEG--------------------HIILHSMHRYLPRLHLVPAEKAVEVIQLNGPGVH 224

Query: 270 TYLFPETEFIAVTAYQNDKITQLKIDNNPFAKGFRDTGNGRREKR 314
           T+ FP+TEF AVTAYQN +ITQLKID NPFAKGFRD G   + +R
Sbjct: 225 TFTFPQTEFFAVTAYQNIQITQLKIDYNPFAKGFRDDGLNNKPQR 269


>gi|158187509 T-box 22 isoform 1 [Homo sapiens]
          Length = 520

 Score =  193 bits (490), Expect = 6e-49
 Identities = 99/220 (45%), Positives = 134/220 (60%), Gaps = 29/220 (13%)

Query: 100 EDDPKVHLEAKELWDQFHKRGTEMVITKSGRRMFPPFKVRCSGLDKKAKYILLMDIIAAD 159
           E D ++ L+  ELW +FH  GTEM+ITK+GRRMFP  +V+  GLD   +Y + +D++  D
Sbjct: 89  EKDIQMELQGSELWKRFHDIGTEMIITKAGRRMFPSVRVKVKGLDPGKQYHVAIDVVPVD 148

Query: 160 DCRYK--FHNSRWMVAGKADPE-MPKRMYIHPDSPATGEQWMSKVVTFHKLKLTNNISDK 216
             RY+  +H+S+WMVAG  D   +  R Y+HPDSP +GE WM ++++F ++KLTNN  D 
Sbjct: 149 SKRYRYVYHSSQWMVAGNTDHLCIIPRFYVHPDSPCSGETWMRQIISFDRMKLTNNEMDD 208

Query: 217 HGFTLAFPSDHATWQGNYSFGTQTILNSMHKYQPRFHIVR------ANDILKLPYSTFRT 270
            G                      IL SMHKY+PR H++        + I  LP    +T
Sbjct: 209 KG--------------------HIILQSMHKYKPRVHVIEQGSSVDLSQIQSLPTEGVKT 248

Query: 271 YLFPETEFIAVTAYQNDKITQLKIDNNPFAKGFRDTGNGR 310
           + F ETEF  VTAYQN +IT+LKI+ NPFAKGFRDTG  R
Sbjct: 249 FSFKETEFTTVTAYQNQQITKLKIERNPFAKGFRDTGRNR 288


>gi|18375603 T-box 22 isoform 1 [Homo sapiens]
          Length = 520

 Score =  193 bits (490), Expect = 6e-49
 Identities = 99/220 (45%), Positives = 134/220 (60%), Gaps = 29/220 (13%)

Query: 100 EDDPKVHLEAKELWDQFHKRGTEMVITKSGRRMFPPFKVRCSGLDKKAKYILLMDIIAAD 159
           E D ++ L+  ELW +FH  GTEM+ITK+GRRMFP  +V+  GLD   +Y + +D++  D
Sbjct: 89  EKDIQMELQGSELWKRFHDIGTEMIITKAGRRMFPSVRVKVKGLDPGKQYHVAIDVVPVD 148

Query: 160 DCRYK--FHNSRWMVAGKADPE-MPKRMYIHPDSPATGEQWMSKVVTFHKLKLTNNISDK 216
             RY+  +H+S+WMVAG  D   +  R Y+HPDSP +GE WM ++++F ++KLTNN  D 
Sbjct: 149 SKRYRYVYHSSQWMVAGNTDHLCIIPRFYVHPDSPCSGETWMRQIISFDRMKLTNNEMDD 208

Query: 217 HGFTLAFPSDHATWQGNYSFGTQTILNSMHKYQPRFHIVR------ANDILKLPYSTFRT 270
            G                      IL SMHKY+PR H++        + I  LP    +T
Sbjct: 209 KG--------------------HIILQSMHKYKPRVHVIEQGSSVDLSQIQSLPTEGVKT 248

Query: 271 YLFPETEFIAVTAYQNDKITQLKIDNNPFAKGFRDTGNGR 310
           + F ETEF  VTAYQN +IT+LKI+ NPFAKGFRDTG  R
Sbjct: 249 FSFKETEFTTVTAYQNQQITKLKIERNPFAKGFRDTGRNR 288


>gi|4507339 transcription factor T [Homo sapiens]
          Length = 435

 Score =  186 bits (471), Expect = 9e-47
 Identities = 97/212 (45%), Positives = 126/212 (59%), Gaps = 25/212 (11%)

Query: 94  EPEEEVEDDPKVHLEAKELWDQFHKRGTEMVITKSGRRMFPPFKVRCSGLDKKAKYILLM 153
           E  +  E + +V LE  ELW +F +   EM++TK+GRRMFP  KV  SGLD  A Y  L+
Sbjct: 33  EKGDPTERELRVGLEESELWLRFKELTNEMIVTKNGRRMFPVLKVNVSGLDPNAMYSFLL 92

Query: 154 DIIAADDCRYKFHNSRWMVAGKADPEMPKRMYIHPDSPATGEQWMSKVVTFHKLKLTNNI 213
           D +AAD+ R+K+ N  W+  GK +P+ P  +YIHPDSP  G  WM   V+F K+KLTN +
Sbjct: 93  DFVAADNHRWKYVNGEWVPGGKPEPQAPSCVYIHPDSPNFGAHWMKAPVSFSKVKLTNKL 152

Query: 214 SDKHGFTLAFPSDHATWQGNYSFGTQTILNSMHKYQPRFHIVRANDILKLPYSTFRTYLF 273
           +                      G Q +LNS+HKY+PR HIVR       P     ++ F
Sbjct: 153 NG---------------------GGQIMLNSLHKYEPRIHIVRVGG----PQRMITSHCF 187

Query: 274 PETEFIAVTAYQNDKITQLKIDNNPFAKGFRD 305
           PET+FIAVTAYQN++IT LKI  NPFAK F D
Sbjct: 188 PETQFIAVTAYQNEEITALKIKYNPFAKAFLD 219


>gi|5730081 T-box, brain, 1 [Homo sapiens]
          Length = 682

 Score =  181 bits (459), Expect = 2e-45
 Identities = 115/300 (38%), Positives = 151/300 (50%), Gaps = 53/300 (17%)

Query: 11  PGTSMAYHPFLPHRAPDFAMSAVLGHQPPFFPALTLPPNGAAALSLPGALAKPIMDQLVG 70
           P   MA+HP + + A +  +S      P  +P    P                   Q  G
Sbjct: 142 PSRYMAHHPVITNGAYNSLLS---NSSPQGYPTAGYP-----------------YPQQYG 181

Query: 71  AAETGIPFSSLGP-QAHLRPLKTMEPEEEVEDDPKVHLEAKELWDQFHKRGTEMVITKSG 129
            +  G PF      Q  L P K            +V+L  + LW +FH+  TEM+ITK G
Sbjct: 182 HSYQGAPFYQFSSTQPGLVPGKA-----------QVYLCNRPLWLKFHRHQTEMIITKQG 230

Query: 130 RRMFPPFKVRCSGLDKKAKYILLMDIIAADDCRYKFHNSRWMVAGKADPEMP-KRMYIHP 188
           RRMFP      SGLD  A Y + +D+I AD   ++F   +W+  GKAD  +   R+Y+HP
Sbjct: 231 RRMFPFLSFNISGLDPTAHYNIFVDVILADPNHWRFQGGKWVPCGKADTNVQGNRVYMHP 290

Query: 189 DSPATGEQWMSKVVTFHKLKLTNNISDKHGFTLAFPSDHATWQGNYSFGTQTILNSMHKY 248
           DSP TG  WM + ++F KLKLTNN                    + + G   +L S+HKY
Sbjct: 291 DSPNTGAHWMRQEISFGKLKLTNNKG-----------------ASNNNGQMVVLQSLHKY 333

Query: 249 QPRFHIVRANDILKLPYS---TFRTYLFPETEFIAVTAYQNDKITQLKIDNNPFAKGFRD 305
           QPR H+V  N+      S     +T+ FPET+FIAVTAYQN  ITQLKID+NPFAKGFRD
Sbjct: 334 QPRLHVVEVNEDGTEDTSQPGRVQTFTFPETQFIAVTAYQNTDITQLKIDHNPFAKGFRD 393


>gi|7019549 T-box 21 [Homo sapiens]
          Length = 535

 Score =  177 bits (448), Expect = 4e-44
 Identities = 111/282 (39%), Positives = 146/282 (51%), Gaps = 36/282 (12%)

Query: 38  PP--FFPALTLPPNGAAALSLPGALAKPIMDQLVGAAETGIPFSSLGPQAHLRPLKTMEP 95
           PP  F  A   PP   AA   PGA             + G  +++  P+A L P     P
Sbjct: 67  PPSRFLGAYAYPPRPQAA-GFPGAGESFPPPADAEGYQPGEGYAAPDPRAGLYP----GP 121

Query: 96  EE--------EVEDDPKVHLEAKELWDQFHKRGTEMVITKSGRRMFPPFKVRCSGLDKKA 147
            E        EV    +V L    LW +F++  TEM+ITK GRRMFP      +GL+  +
Sbjct: 122 REDYALPAGLEVSGKLRVALNNHLLWSKFNQHQTEMIITKQGRRMFPFLSFTVAGLEPTS 181

Query: 148 KYILLMDIIAADDCRYKFHNSRWMVAGKADPEMP-KRMYIHPDSPATGEQWMSKVVTFHK 206
            Y + +D++  D   +++ + +W+  GKA+  MP  R+Y+HPDSP TG  WM + V+F K
Sbjct: 182 HYRMFVDVVLVDQHHWRYQSGKWVQCGKAEGSMPGNRLYVHPDSPNTGAHWMRQEVSFGK 241

Query: 207 LKLTNNISDKHGFTLAFPSDHATWQGNYSFGTQTILNSMHKYQPRFHIVRAND---ILKL 263
           LKLTNN    +  T                    +L S+HKYQPR HIV  ND       
Sbjct: 242 LKLTNNKGASNNVT-----------------QMIVLQSLHKYQPRLHIVEVNDGEPEAAC 284

Query: 264 PYSTFRTYLFPETEFIAVTAYQNDKITQLKIDNNPFAKGFRD 305
             S    + F ET+FIAVTAYQN +ITQLKIDNNPFAKGFR+
Sbjct: 285 NASNTHIFTFQETQFIAVTAYQNAEITQLKIDNNPFAKGFRE 326


>gi|22538470 eomesodermin [Homo sapiens]
          Length = 686

 Score =  174 bits (441), Expect = 3e-43
 Identities = 96/207 (46%), Positives = 126/207 (60%), Gaps = 25/207 (12%)

Query: 105 VHLEAKELWDQFHKRGTEMVITKSGRRMFPPFKVRCSGLDKKAKYILLMDIIAADDCRYK 164
           V+L  + LW +FH+  TEM+ITK GRRMFP      +GL+  A Y + ++++ AD   ++
Sbjct: 269 VYLCNRPLWLKFHRHQTEMIITKQGRRMFPFLSFNINGLNPTAHYNVFVEVVLADPNHWR 328

Query: 165 FHNSRWMVAGKADPEMP-KRMYIHPDSPATGEQWMSKVVTFHKLKLTNNISDKHGFTLAF 223
           F   +W+  GKAD  M   +MY+HP+SP TG  WM + ++F KLKLTNN           
Sbjct: 329 FQGGKWVTCGKADNNMQGNKMYVHPESPNTGSHWMRQEISFGKLKLTNN----------- 377

Query: 224 PSDHATWQGNYSFGTQTI-LNSMHKYQPRFHIVRAN----DILKLPYSTFRTYLFPETEF 278
                  +G  +  TQ I L S+HKYQPR HIV       + L  P  T +T+ F ET+F
Sbjct: 378 -------KGANNNNTQMIVLQSLHKYQPRLHIVEVTEDGVEDLNEPSKT-QTFTFSETQF 429

Query: 279 IAVTAYQNDKITQLKIDNNPFAKGFRD 305
           IAVTAYQN  ITQLKID+NPFAKGFRD
Sbjct: 430 IAVTAYQNTDITQLKIDHNPFAKGFRD 456



 Score = 39.7 bits (91), Expect = 0.010
 Identities = 45/158 (28%), Positives = 63/158 (39%), Gaps = 15/158 (9%)

Query: 520 LHPSQFAMGGAFSSMAAAGMGPLLATVSGASTGVSGLDSTAMASAAAAQGLSGASAATLP 579
           L  ++   GG+   + +A   P    +  AS   SG  S    S   A   +GA AA L 
Sbjct: 22  LESARGGSGGSAGHLPSAAPSPQKLDLDKASKKFSGSLSCEAVSGEPAAASAGAPAAMLS 81

Query: 580 FHLQQHVLASQGLAMSPF------GSLFPYPYTYMAAAAAASSAAASSSVHRHPFLNLNT 633
                   AS      P       GS         AAAAAA++AAA+++  R+   +L++
Sbjct: 82  DTDAGDAFASAAAVAKPGPPDGRKGSPCGEEELPSAAAAAAAAAAAAAATARYSMDSLSS 141

Query: 634 MRPRLRYSPYSIPVPVPDGSSLLT--TALPSMAAAAGP 669
            R       Y +  P P GS L    +  P  AAA  P
Sbjct: 142 ER-------YYLQSPGPQGSELAAPCSLFPYQAAAGAP 172


>gi|4827024 T-box 19 [Homo sapiens]
          Length = 448

 Score =  166 bits (419), Expect = 9e-41
 Identities = 88/212 (41%), Positives = 119/212 (56%), Gaps = 25/212 (11%)

Query: 94  EPEEEVEDDPKVHLEAKELWDQFHKRGTEMVITKSGRRMFPPFKVRCSGLDKKAKYILLM 153
           E  +  E   ++ LE   LW +F +   EM++TK+GRRMFP  K+  +GLD  A Y LL+
Sbjct: 32  EKGDPTEKQLQIILEDAPLWQRFKEVTNEMIVTKNGRRMFPVLKISVTGLDPNAMYSLLL 91

Query: 154 DIIAADDCRYKFHNSRWMVAGKADPEMPKRMYIHPDSPATGEQWMSKVVTFHKLKLTNNI 213
           D +  D  R+K+ N  W+ AGK +      +YIHPDSP  G  WM   ++F K+KLTN +
Sbjct: 92  DFVPTDSHRWKYVNGEWVPAGKPEVSSHSCVYIHPDSPNFGAHWMKAPISFSKVKLTNKL 151

Query: 214 SDKHGFTLAFPSDHATWQGNYSFGTQTILNSMHKYQPRFHIVRANDILKLPYSTFRTYLF 273
           +                      G Q +LNS+HKY+P+ HIVR     ++         F
Sbjct: 152 NG---------------------GGQIMLNSLHKYEPQVHIVRVGSAHRM----VTNCSF 186

Query: 274 PETEFIAVTAYQNDKITQLKIDNNPFAKGFRD 305
           PET+FIAVTAYQN++IT LKI  NPFAK F D
Sbjct: 187 PETQFIAVTAYQNEEITALKIKYNPFAKAFLD 218


>gi|158187511 T-box 22 isoform 2 [Homo sapiens]
          Length = 400

 Score =  154 bits (390), Expect = 2e-37
 Identities = 81/188 (43%), Positives = 110/188 (58%), Gaps = 29/188 (15%)

Query: 132 MFPPFKVRCSGLDKKAKYILLMDIIAADDCRYKF--HNSRWMVAGKADPE-MPKRMYIHP 188
           MFP  +V+  GLD   +Y + +D++  D  RY++  H+S+WMVAG  D   +  R Y+HP
Sbjct: 1   MFPSVRVKVKGLDPGKQYHVAIDVVPVDSKRYRYVYHSSQWMVAGNTDHLCIIPRFYVHP 60

Query: 189 DSPATGEQWMSKVVTFHKLKLTNNISDKHGFTLAFPSDHATWQGNYSFGTQTILNSMHKY 248
           DSP +GE WM ++++F ++KLTNN  D  G                      IL SMHKY
Sbjct: 61  DSPCSGETWMRQIISFDRMKLTNNEMDDKG--------------------HIILQSMHKY 100

Query: 249 QPRFHIVRA------NDILKLPYSTFRTYLFPETEFIAVTAYQNDKITQLKIDNNPFAKG 302
           +PR H++        + I  LP    +T+ F ETEF  VTAYQN +IT+LKI+ NPFAKG
Sbjct: 101 KPRVHVIEQGSSVDLSQIQSLPTEGVKTFSFKETEFTTVTAYQNQQITKLKIERNPFAKG 160

Query: 303 FRDTGNGR 310
           FRDTG  R
Sbjct: 161 FRDTGRNR 168


>gi|146219843 Snf2-related CBP activator protein [Homo sapiens]
          Length = 3230

 Score = 53.5 bits (127), Expect = 7e-07
 Identities = 66/230 (28%), Positives = 90/230 (39%), Gaps = 15/230 (6%)

Query: 472  ALPGKEAFAPLTVQTDAAAAHLAQGPLPGLGFAPGLAGQQFFNGHPLFLHPSQFAMGGAF 531
            A PG  + AP      A+A  L      GL  AP L+  Q   GHPL L P+   + G  
Sbjct: 1486 AAPGPPSLAPSGASPSASALTL------GLATAPSLSSSQT-PGHPLLLAPTSSHVPGLN 1538

Query: 532  SSMAAAGMGPLLATVSGASTGVSGLDSTAMASAAAAQGLSGASAATLPFHLQQHVLASQG 591
            S++A A   P+L   S  ++      + A A A+     S AS A            +  
Sbjct: 1539 STVAPA-CSPVLVPASALASPFPSAPNPAPAQASLLAPASSASQALATPLAPMAAPQTAI 1597

Query: 592  LAMSPFGSLFPYPYTYMAAAAAASSAAASSSVHRHPFLNLNTMRPRLRYSPYSIPVPVPD 651
            LA SP   L P P    +  AA   A++ + V   P +  ++       S   +P P P 
Sbjct: 1598 LAPSPAPPLAPLPVLAPSPGAAPVLASSQTPV---PVMAPSSTPGTSLASASPVPAPTPV 1654

Query: 652  -GSSLLTTALPSMAAAAGPLDGKVAALAASPASVAVDSGSELNSRSSTLS 700
               S   T LP+   +  P       LA +PA      GS   S S TLS
Sbjct: 1655 LAPSSTQTMLPAPVPSPLPSPASTQTLALAPALAPTLGGS---SPSQTLS 1701



 Score = 37.4 bits (85), Expect = 0.051
 Identities = 66/299 (22%), Positives = 99/299 (33%), Gaps = 45/299 (15%)

Query: 432  SPDSRHSPATISSSTRGLG-----AEERRSPVREGTAPAKVEEARALPGKEAF----APL 482
            +P S H P   S+           A    SP      PA  + +   P   A      PL
Sbjct: 1528 APTSSHVPGLNSTVAPACSPVLVPASALASPFPSAPNPAPAQASLLAPASSASQALATPL 1587

Query: 483  TVQTDAAAAHLAQGPLPGLGFAPGLAGQQFFNGHPLFLHPSQFAMGGAFSSMAAAGMGPL 542
                    A LA  P P L   P LA                           + G  P+
Sbjct: 1588 APMAAPQTAILAPSPAPPLAPLPVLA--------------------------PSPGAAPV 1621

Query: 543  LATVSGASTGVSGLDSTAMASAAAAQGLSGASAATLPFHLQQHVLASQGLAMSPFGSLFP 602
            LA+ S     V    ST   S A+A  +   +    P        ++Q +  +P  S  P
Sbjct: 1622 LAS-SQTPVPVMAPSSTPGTSLASASPVPAPTPVLAPS-------STQTMLPAPVPSPLP 1673

Query: 603  YPYTYMAAAAAASSAAASSSVHRHPFLNLNTMRPRLRYSPYSIPVPVPDGSSLLTTALPS 662
             P +    A A + A           L+L T  P+  +   ++ +     SSL+ T   +
Sbjct: 1674 SPASTQTLALAPALAPTLGGSSPSQTLSLGTGNPQGPFPTQTLSLT--PASSLVPTPAQT 1731

Query: 663  MAAAAGPLDGKVAALAASPASVAVDSGSELNSRSSTLSSSSMSLSPKLCAEKEAATSEL 721
            ++ A GP  G    L+ +PA     +     + + TL+ +  S S  L A     T  L
Sbjct: 1732 LSLAPGPPLGPTQTLSLAPAPPLAPASPVGPAPAHTLTLAPASSSASLLAPASVQTLTL 1790



 Score = 31.2 bits (69), Expect = 3.6
 Identities = 61/247 (24%), Positives = 88/247 (35%), Gaps = 34/247 (13%)

Query: 478  AFAPLTVQTDAAAAHLAQGPLPGLGFAPGLAGQQFFNGHPLFLHPSQFAMGGAFSSMAAA 537
            A APLT+   A     A GP       P LA        P    P   A  GA  S +A 
Sbjct: 1451 ASAPLTIPISAPLTVSASGPALLTSVTPPLAPVV-----PAAPGPPSLAPSGASPSASAL 1505

Query: 538  GMGPLLATVSGASTGVSGLDSTAMASAAAAQGLSGASAATLPFHLQQHVLASQGLAMSPF 597
             +G  LAT    S+  S      +  A  +  + G ++   P      VL       SPF
Sbjct: 1506 TLG--LATAPSLSS--SQTPGHPLLLAPTSSHVPGLNSTVAP--ACSPVLVPASALASPF 1559

Query: 598  GSLFPYPYTYMAAAAAASSAAASSSVHRHPFLNLNTMRPRLRYSPYSIPVPVPDGSSLLT 657
             S  P P    A+  A +S+A+ +                   +P + P+  P  + L  
Sbjct: 1560 PSA-PNPAPAQASLLAPASSASQALA-----------------TPLA-PMAAPQTAILA- 1599

Query: 658  TALPSMAAAAGPLDGKVAALAASPASVAVDSGSELNSRSSTLSSSSMSLSPKLCAEKEAA 717
               PS A    PL     +  A+P   +  +   + + SST  +S  S SP        A
Sbjct: 1600 ---PSPAPPLAPLPVLAPSPGAAPVLASSQTPVPVMAPSSTPGTSLASASPVPAPTPVLA 1656

Query: 718  TSELQSI 724
             S  Q++
Sbjct: 1657 PSSTQTM 1663


>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
          Length = 1020

 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 43/179 (24%), Positives = 79/179 (44%), Gaps = 9/179 (5%)

Query: 316 QLTLQSMRVFDERHKKENGTSDESSSEQAAFNCFAQASSPAASTVGTSNLKDLCPSEGES 375
           Q+T +     ++  K+E G  +E   E+ A     +  SP A    +   +   P + E+
Sbjct: 465 QVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPVKEEA 524

Query: 376 DAEAESKEEHGPEACDAAKI-STTTSEEPCRDKGSPAVKAHLFAAERPRDSGRLDKASPD 434
            + AE+K     EA   A++ S   ++ P +++     +A   + E+       +  SP+
Sbjct: 525 KSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAK--SPEKEEAKSPAEVKSPE 582

Query: 435 SRHSPA--TISSSTRGLGAEERRSPVR-EGTAPAKVEEARALPGKEAFAPLTVQTDAAA 490
              SPA     S       E+ +SPV+ E  +PA   EA++   +EA +P  V++   A
Sbjct: 583 KAKSPAKEEAKSPAEAKSPEKAKSPVKEEAKSPA---EAKSPVKEEAKSPAEVKSPEKA 638



 Score = 37.7 bits (86), Expect = 0.039
 Identities = 35/144 (24%), Positives = 56/144 (38%), Gaps = 12/144 (8%)

Query: 359 TVGTSNLKDLCPSEGESDAEAESKEEHGPEACDAAKISTTTSEEPCRDKGSPAVKAHLFA 418
           T  T   +++   E +   E E KEE G E  +A      T   P  +  SP  +A    
Sbjct: 461 TEETQVTEEVTEEEEKEAKEEEGKEEEGGEEEEAEGGEEETKSPPAEEAASPEKEAKSPV 520

Query: 419 AERPRDSGRLDKASPDSRHSPATISS--STRGLGAEERRSP-------VREGTAPAKV-- 467
            E  +          +   SPA + S    +    EE +SP         E  +PA+V  
Sbjct: 521 KEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKS 580

Query: 468 -EEARALPGKEAFAPLTVQTDAAA 490
            E+A++   +EA +P   ++   A
Sbjct: 581 PEKAKSPAKEEAKSPAEAKSPEKA 604



 Score = 35.8 bits (81), Expect = 0.15
 Identities = 41/168 (24%), Positives = 70/168 (41%), Gaps = 16/168 (9%)

Query: 336 SDESSSEQAAFNCFAQASSPAASTVGTSNLKDLCPSEGESDAEAESKEEHGPEACDAAKI 395
           ++  S E+A      +A SPA +    S +K+   S  E  +  ++K     EA    K 
Sbjct: 596 AEAKSPEKAKSPVKEEAKSPAEAK---SPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKA 652

Query: 396 STTTSEEP-CRDKGSPAVKAHLFAAERPRDSGRLDKASPDSRHSPATISSSTRGLGAEER 454
            +   EE    +K    VKA   + E+ +   + +  SP+   SP    + +     E+ 
Sbjct: 653 KSPEKEEAKSPEKAKSPVKAEAKSPEKAKSPVKAEAKSPEKAKSPVKEEAKS----PEKA 708

Query: 455 RSPVREGT-----APAKVEEARALPGKEAFAPLTVQTDAAAAHLAQGP 497
           +SPV+E       A + V+E    P K   A   V+ +A +   A+ P
Sbjct: 709 KSPVKEEAKSPEKAKSPVKEEAKTPEK---AKSPVKEEAKSPEKAKSP 753



 Score = 31.2 bits (69), Expect = 3.6
 Identities = 26/126 (20%), Positives = 46/126 (36%), Gaps = 14/126 (11%)

Query: 370 PSEGESDAEAESKEEHGPEACDAAKISTTTSEEPCRDKGSPAVKAHLFAAERPRDSGRLD 429
           P + +S  +A++ +   PEA   AK    +  +   +K    VK  + + E+ +   + D
Sbjct: 747 PEKAKSPEKAKTLDVKSPEAKTPAKEEARSPADKFPEKAKSPVKEEVKSPEKAKSPLKED 806

Query: 430 KASPDSR--------------HSPATISSSTRGLGAEERRSPVREGTAPAKVEEARALPG 475
             +P+                  P  +        AEE ++P    T   K  +    P 
Sbjct: 807 AKAPEKEIPKKEEVKSPVKEEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPK 866

Query: 476 KEAFAP 481
           KEA  P
Sbjct: 867 KEAPKP 872


>gi|7662228 synaptosomal-associated protein, 91kDa homolog [Homo
           sapiens]
          Length = 907

 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 100/389 (25%), Positives = 142/389 (36%), Gaps = 53/389 (13%)

Query: 333 NGTSDESSSEQAAFNCFAQASS--PAASTVGTSNLKDLCPSEGESDAEAESKEEHGPEAC 390
           N T  ++       + FA AS+  P +++  +S+L DL P      A A +     P A 
Sbjct: 315 NSTPAKTIDTSPPVDLFATASAAVPVSTSKPSSDLLDLQPDFSSGGAAAAAAPAPPPPAG 374

Query: 391 DAAKISTTTSEEPCRDKGSPAVKAHL---FAAER--PRDSGRLDKASPDSRHSPATISSS 445
            A        E+      S   +A +   FA E   P  +  +  AS  S  +  T+++ 
Sbjct: 375 GATAWGDLLGEDSLAALSSVPSEAQISDPFAPEPTPPTTTAEIATASA-SASTTTTVTAV 433

Query: 446 TRGLGAEERRSPVREGTAPAKVEEARALPGKEAFAPLTVQTDAAAAHLAQGPLPGLGFAP 505
           T  +           G APA  E A A        P T    AAA     G  P   FAP
Sbjct: 434 TAEVDLFGDAFAASPGEAPAASEGAAA--------PATPTPVAAALDACSGNDP---FAP 482

Query: 506 GLAGQQFFNGHPLF-LHPSQFAMGGAFSSMAAAGMGPLLATVSGASTGVSGLDSTAMASA 564
                +      LF + P + ++     + + A   P+ AT    +  V+   +   A+ 
Sbjct: 483 SEGSAEAAPELDLFAMKPPETSVPVVTPTASTAP--PVPATAPSPAPAVAAAAAATTAAT 540

Query: 565 AAAQGLSGASAATLPFHLQQHVLASQGLAMSPFGSLFPYPYTYMAAAAAASSAAASSSVH 624
           AAA   +  SAAT           +   A+  FG LF    T   AAA    AA S  + 
Sbjct: 541 AAATTTTTTSAAT---------ATTAPPALDIFGDLF--ESTPEVAAAPKPDAAPSIDLF 589

Query: 625 RHPFLNLNTMRPRLRYSPYSIPVPVPDGSSLLTTALPSMAAAAGPLDGKVAALAASPASV 684
                +          SP     PVP+ S  LT  L S+ A A P     A+ A   +S 
Sbjct: 590 STDAFS----------SPPQGASPVPESS--LTADLLSVDAFAAPSPATTASPAKVDSSG 637

Query: 685 AVD--------SGSELNSRSSTLSSSSMS 705
            +D        S SE    S   SSSS S
Sbjct: 638 VIDLFGDAFGSSASEPQPASQAASSSSAS 666


>gi|19111150 angiomotin isoform 2 [Homo sapiens]
          Length = 675

 Score = 43.5 bits (101), Expect = 7e-04
 Identities = 46/163 (28%), Positives = 67/163 (41%), Gaps = 23/163 (14%)

Query: 535 AAAGMGPLLATVSGASTGVSGLDSTAMASAAAAQGLSGASAATLPFHLQQHVLASQGLAM 594
           AAA    + AT +  +T +      A+A+AAA    +  S AT          A+   A+
Sbjct: 480 AAATAAAITATAATITTTMVAAAPVAVAAAAAPAAAAAPSPAT---------AAATAAAV 530

Query: 595 SPFGS-LFPYPYTYMAAAAAASSAAASSSVHRHPFLNLNTMRPRLRYSPYSIPVPVP--- 650
           SP  +   P   +  +AAA A SAAA+++V   P        P    +P  +PVP P   
Sbjct: 531 SPAAAGQIPAAASVASAAAVAPSAAAAAAVQVAP------AAPAPVPAPALVPVPAPAAA 584

Query: 651 ----DGSSLLTTALPSMAAAAGPLDGKVAALAASPASVAVDSG 689
                  +   T+ P++A    P      A A  PAS A   G
Sbjct: 585 QASAPAQTQAPTSAPAVAPTPAPTPTPAVAQAEVPASPATGPG 627



 Score = 32.0 bits (71), Expect = 2.1
 Identities = 42/159 (26%), Positives = 63/159 (39%), Gaps = 26/159 (16%)

Query: 526 AMGGAFSSMAAAGMGPLLATVSGASTGVSG---LDSTAMASAAAAQGLSGASAATLPFHL 582
           A+  A +  AAA   P  A  + A+   +    + + A  ++AAA   S A+AA +    
Sbjct: 505 AVAAAAAPAAAAAPSPATAAATAAAVSPAAAGQIPAAASVASAAAVAPSAAAAAAVQ--- 561

Query: 583 QQHVLASQGLAMSPFGSLFPYPYTYMAAAAAASSAAASSSVHRHPFLNLNTMRPRLRYSP 642
               +A    A  P  +L P P    A AAA +SA A +           T  P +  +P
Sbjct: 562 ----VAPAAPAPVPAPALVPVP----APAAAQASAPAQTQA--------PTSAPAV--AP 603

Query: 643 YSIPVPVPDGSSLLTTALPSMAAAAGPLDGKVAALAASP 681
              P P P  +     A P  A   GP    + +L  +P
Sbjct: 604 TPAPTPTPAVAQAEVPASP--ATGPGPHRLSIPSLTCNP 640


>gi|166064029 angiomotin isoform 1 [Homo sapiens]
          Length = 1084

 Score = 43.5 bits (101), Expect = 7e-04
 Identities = 46/163 (28%), Positives = 67/163 (41%), Gaps = 23/163 (14%)

Query: 535  AAAGMGPLLATVSGASTGVSGLDSTAMASAAAAQGLSGASAATLPFHLQQHVLASQGLAM 594
            AAA    + AT +  +T +      A+A+AAA    +  S AT          A+   A+
Sbjct: 889  AAATAAAITATAATITTTMVAAAPVAVAAAAAPAAAAAPSPAT---------AAATAAAV 939

Query: 595  SPFGS-LFPYPYTYMAAAAAASSAAASSSVHRHPFLNLNTMRPRLRYSPYSIPVPVP--- 650
            SP  +   P   +  +AAA A SAAA+++V   P        P    +P  +PVP P   
Sbjct: 940  SPAAAGQIPAAASVASAAAVAPSAAAAAAVQVAP------AAPAPVPAPALVPVPAPAAA 993

Query: 651  ----DGSSLLTTALPSMAAAAGPLDGKVAALAASPASVAVDSG 689
                   +   T+ P++A    P      A A  PAS A   G
Sbjct: 994  QASAPAQTQAPTSAPAVAPTPAPTPTPAVAQAEVPASPATGPG 1036



 Score = 32.0 bits (71), Expect = 2.1
 Identities = 42/159 (26%), Positives = 63/159 (39%), Gaps = 26/159 (16%)

Query: 526  AMGGAFSSMAAAGMGPLLATVSGASTGVSG---LDSTAMASAAAAQGLSGASAATLPFHL 582
            A+  A +  AAA   P  A  + A+   +    + + A  ++AAA   S A+AA +    
Sbjct: 914  AVAAAAAPAAAAAPSPATAAATAAAVSPAAAGQIPAAASVASAAAVAPSAAAAAAVQ--- 970

Query: 583  QQHVLASQGLAMSPFGSLFPYPYTYMAAAAAASSAAASSSVHRHPFLNLNTMRPRLRYSP 642
                +A    A  P  +L P P    A AAA +SA A +           T  P +  +P
Sbjct: 971  ----VAPAAPAPVPAPALVPVP----APAAAQASAPAQTQA--------PTSAPAV--AP 1012

Query: 643  YSIPVPVPDGSSLLTTALPSMAAAAGPLDGKVAALAASP 681
               P P P  +     A P  A   GP    + +L  +P
Sbjct: 1013 TPAPTPTPAVAQAEVPASP--ATGPGPHRLSIPSLTCNP 1049


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.128    0.374 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 30,025,106
Number of Sequences: 37866
Number of extensions: 1476583
Number of successful extensions: 8002
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 53
Number of HSP's successfully gapped in prelim test: 260
Number of HSP's that attempted gapping in prelim test: 7188
Number of HSP's gapped (non-prelim): 863
length of query: 743
length of database: 18,247,518
effective HSP length: 110
effective length of query: 633
effective length of database: 14,082,258
effective search space: 8914069314
effective search space used: 8914069314
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.