BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|47271443 splicing factor, arginine/serine-rich 2 [Homo sapiens] (221 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|47271443 splicing factor, arginine/serine-rich 2 [Homo sapiens] 437 e-123 gi|15055543 splicing factor, arginine/serine-rich 2B [Homo sapiens] 288 2e-78 gi|72534660 splicing factor, arginine/serine-rich 7 [Homo sapiens] 131 5e-31 gi|16905517 FUS interacting protein (serine-arginine rich) 1 iso... 129 3e-30 gi|148612890 serine-arginine repressor protein [Homo sapiens] 127 6e-30 gi|20127499 arginine/serine-rich splicing factor 6 [Homo sapiens] 103 9e-23 gi|5730079 FUS interacting protein (serine-arginine rich) 1 isof... 100 8e-22 gi|169161980 PREDICTED: similar to FUS interacting protein (seri... 99 2e-21 gi|29568103 U1 small nuclear ribonucleoprotein 70 kDa [Homo sapi... 98 6e-21 gi|4506901 splicing factor, arginine/serine-rich 3 [Homo sapiens] 96 2e-20 gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens] 95 4e-20 gi|86991440 splicing factor, arginine/serine-rich 5 [Homo sapiens] 94 7e-20 gi|86991438 splicing factor, arginine/serine-rich 5 [Homo sapiens] 94 7e-20 gi|133922600 splicing factor, arginine/serine-rich 16 [Homo sapi... 86 3e-17 gi|4502847 cold inducible RNA binding protein [Homo sapiens] 86 3e-17 gi|119226260 calcium homeostasis endoplasmic reticulum protein [... 85 4e-17 gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo sapi... 85 6e-17 gi|6857826 RNA-binding protein S1, serine-rich domain [Homo sapi... 84 1e-16 gi|18379334 RNA-binding protein S1, serine-rich domain [Homo sap... 84 1e-16 gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ... 83 2e-16 gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [... 83 2e-16 gi|56699409 RNA binding motif protein, X-linked [Homo sapiens] 83 2e-16 gi|4759098 splicing factor, arginine/serine-rich 10 [Homo sapiens] 82 3e-16 gi|242117971 RNA binding motif protein, X-linked-like 1 [Homo sa... 82 4e-16 gi|21361809 RNA binding motif protein, X-linked-like 1 [Homo sap... 82 4e-16 gi|4759100 splicing factor, arginine/serine-rich 11 [Homo sapiens] 81 8e-16 gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] 80 2e-15 gi|38146113 arginine/serine-rich coiled-coil 2 isoform b [Homo s... 79 3e-15 gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo s... 79 3e-15 gi|9558733 transformer-2 alpha [Homo sapiens] 78 7e-15 >gi|47271443 splicing factor, arginine/serine-rich 2 [Homo sapiens] Length = 221 Score = 437 bits (1125), Expect = e-123 Identities = 221/221 (100%), Positives = 221/221 (100%) Query: 1 MSYGRPPPDVEGMTSLKVDNLTYRTSPDTLRRVFEKYGRVGDVYIPRDRYTKESRGFAFV 60 MSYGRPPPDVEGMTSLKVDNLTYRTSPDTLRRVFEKYGRVGDVYIPRDRYTKESRGFAFV Sbjct: 1 MSYGRPPPDVEGMTSLKVDNLTYRTSPDTLRRVFEKYGRVGDVYIPRDRYTKESRGFAFV 60 Query: 61 RFHDKRDAEDAMDAMDGAVLDGRELRVQMARYGRPPDSHHSRRGPPPRRYGGGGYGRRSR 120 RFHDKRDAEDAMDAMDGAVLDGRELRVQMARYGRPPDSHHSRRGPPPRRYGGGGYGRRSR Sbjct: 61 RFHDKRDAEDAMDAMDGAVLDGRELRVQMARYGRPPDSHHSRRGPPPRRYGGGGYGRRSR 120 Query: 121 SPRRRRRSRSRSRSRSRSRSRSRYSRSKSRSRTRSRSRSTSKSRSARRSKSKSSSVSRSR 180 SPRRRRRSRSRSRSRSRSRSRSRYSRSKSRSRTRSRSRSTSKSRSARRSKSKSSSVSRSR Sbjct: 121 SPRRRRRSRSRSRSRSRSRSRSRYSRSKSRSRTRSRSRSTSKSRSARRSKSKSSSVSRSR 180 Query: 181 SRSRSRSRSRSPPPVSKRESKSRSRSKSPPKSPEEEGAVSS 221 SRSRSRSRSRSPPPVSKRESKSRSRSKSPPKSPEEEGAVSS Sbjct: 181 SRSRSRSRSRSPPPVSKRESKSRSRSKSPPKSPEEEGAVSS 221 >gi|15055543 splicing factor, arginine/serine-rich 2B [Homo sapiens] Length = 282 Score = 288 bits (738), Expect = 2e-78 Identities = 178/285 (62%), Positives = 190/285 (66%), Gaps = 67/285 (23%) Query: 1 MSYGRPPPDVEGMTSLKVDNLTYRTSPDTLRRVFEKYGRVGDVYIPRDRYTKESRGFAFV 60 MS GRPPPDV+GM +LKVDNLTYRTSPD+LRRVFEKYGRVGDVYIPR+ +TK RGFAFV Sbjct: 1 MSCGRPPPDVDGMITLKVDNLTYRTSPDSLRRVFEKYGRVGDVYIPREPHTKAPRGFAFV 60 Query: 61 RFHDKRDAEDAMDAMDGAVLDGRELRVQMARYGRPPDSHHSRRGPPPRRYGGGG------ 114 RFHD+RDA+DA AMDGA LDGRELRVQ+ARYGR D SR+G P R GGG Sbjct: 61 RFHDRRDAQDAEAAMDGAELDGRELRVQVARYGR-RDLPRSRQGEPRGRSRGGGYGRRSR 119 Query: 115 -YGRRSRSPRRRRRSRSR----SRSRSRSR----------------SRSRYSR------- 146 YGRRSRSPRRR RSRSR SRSRSRSR SRSRYSR Sbjct: 120 SYGRRSRSPRRRHRSRSRGPSCSRSRSRSRYRGSRYSRSPYSRSPYSRSRYSRSPYSRSR 179 Query: 147 ------------------------------SKSRSRTRSRSRSTSKSRSARRSKSKSSSV 176 SKS S T SRS STSKS SARR SKSSSV Sbjct: 180 YRESRYGGSHYSSSGYSNSRYSRYHSSRSHSKSGSSTSSRSASTSKSSSARR--SKSSSV 237 Query: 177 SRSRSRSRSRSRSRSPPPVSKRESKSRSRSKSPPKSPEEEGAVSS 221 SRSRSRSRS S +RSPP VSKR+SKSRSRSK PPKSPEEEG +SS Sbjct: 238 SRSRSRSRSSSMTRSPPRVSKRKSKSRSRSKRPPKSPEEEGQMSS 282 >gi|72534660 splicing factor, arginine/serine-rich 7 [Homo sapiens] Length = 238 Score = 131 bits (329), Expect = 5e-31 Identities = 101/229 (44%), Positives = 126/229 (55%), Gaps = 32/229 (13%) Query: 12 GMTSLKVDNLTYRTSPDTLRRVFEKYGRVGDVYIPRDRYTKESRGFAFVRFHDKRDAEDA 71 G T + V NL L R F YG + V+I R+ GFAFV F D RDAEDA Sbjct: 9 GETKVYVGNLGTGAGKGELERAFSYYGPLRTVWIARN-----PPGFAFVEFEDPRDAEDA 63 Query: 72 MDAMDGAVLDGRELRVQMA-------RYGRPPDSHHSRR--GPPPRRYGGGGYGRRSRSP 122 + +DG V+ G +RV+++ R+ RPP +RR P R Y G G + Sbjct: 64 VRGLDGKVICGSRVRVELSTGMPRRSRFDRPP----ARRPFDPNDRCYECGEKGHYAYDC 119 Query: 123 RR---RRRSRSRSRSRSRSRSRSRYSRSKSRSR-TRSRSRSTSKSRSARRSKSKSSSVSR 178 R RRRSRSRSRS SRSR R RYSRS+SRSR RSRS S +SRS +S+S+S+ R Sbjct: 120 HRYSRRRRSRSRSRSHSRSRGR-RYSRSRSRSRGRRSRSASPRRSRSISLRRSRSASLRR 178 Query: 179 SRS---------RSRSRSRSRSPPPVSKRESKSRSRSKSPPKSPEEEGA 218 SRS +S SRSRSRS R S+S+SRS SP +S G+ Sbjct: 179 SRSGSIKGSRYFQSPSRSRSRSRSISRPRSSRSKSRSPSPKRSRSPSGS 227 >gi|16905517 FUS interacting protein (serine-arginine rich) 1 isoform 2 [Homo sapiens] Length = 262 Score = 129 bits (323), Expect = 3e-30 Identities = 99/253 (39%), Positives = 132/253 (52%), Gaps = 48/253 (18%) Query: 3 YGRPPPDVEGMTSLKVDNLTYRTSPDTLRRVFEKYGRVGDVYIPRDRYTKESRGFAFVRF 62 Y RPP TSL V N+ T + LRR F +YG + DVY+P D YT+ RGFA+V+F Sbjct: 4 YLRPPN-----TSLFVRNVADDTRSEDLRREFGRYGPIVDVYVPLDFYTRRPRGFAYVQF 58 Query: 63 HDKRDAEDAMDAMDGAVLDGRELRVQMARYGR-PPDSHHSRRGP---PPRRYGGGGYGRR 118 D RDAEDA+ +D + GR++ +Q A+ R P+ ++ G RY RR Sbjct: 59 EDVRDAEDALHNLDRKWICGRQIEIQFAQGDRKTPNQMKAKEGRNVYSSSRYDDYDRYRR 118 Query: 119 SRS-PRRRRRSRSRS------RSRS-----------RSRSRSRYSRSKSRSRTRSRSRST 160 SRS RRRSRSRS RS S RSRS S R K R+R+ SRS+S Sbjct: 119 SRSRSYERRRSRSRSFDYNYRRSYSPRNSRPTGRPRRSRSHSDNDRFKHRNRSFSRSKSN 178 Query: 161 SKSRSARRSKSKSSSVSRSRSRSRSRSRSRS---------------------PPPVSKRE 199 S+SRS + K + + SRSRS S +++R S PP SK + Sbjct: 179 SRSRSKSQPKKEMKAKSRSRSASHTKTRGTSKTDSKTHYKSGSRYEKESRKKEPPRSKSQ 238 Query: 200 SKSRSRSKSPPKS 212 S+S+SRS+S +S Sbjct: 239 SRSQSRSRSKSRS 251 >gi|148612890 serine-arginine repressor protein [Homo sapiens] Length = 261 Score = 127 bits (320), Expect = 6e-30 Identities = 94/237 (39%), Positives = 131/237 (55%), Gaps = 36/237 (15%) Query: 3 YGRPPPDVEGMTSLKVDNLTYRTSPDTLRRVFEKYGRVGDVYIPRDRYTKESRGFAFVRF 62 Y RPP TSL + N+ T P+ LRR F +YG + DVYIP D YT+ RGFA+V+F Sbjct: 4 YTRPPN-----TSLFIRNVADATRPEDLRREFGRYGPIVDVYIPLDFYTRRPRGFAYVQF 58 Query: 63 HDKRDAEDAMDAMDGAVLDGRELRVQMARYGR--PPDSHHSRRGP-PPRRYGGGGYGRRS 119 D RDAEDA+ ++ + GR++ +Q A+ R P R P P + RRS Sbjct: 59 EDVRDAEDALYNLNRKWVCGRQIEIQFAQGDRKTPGQMKSKERHPCSPSDH------RRS 112 Query: 120 RSP-RRRRRSRSRSRSRSRSRSRS-------RYSRSKSRSRTRSRSRSTSKSRSARRSKS 171 RSP +RR RSRS S R+R RS S R+S S+S+SR++S R ++ +R +R + Sbjct: 113 RSPSQRRTRSRSSSWGRNRRRSDSLKESRHRRFSYSQSKSRSKSLPRRSTSARQSRTPRR 172 Query: 172 KSSSVSRSRS-----RSRSRSRSRSPPPVSKRESKSRSRS---------KSPPKSPE 214 S RSRS RS+S +S+S P + S ++SRS +SP KSP+ Sbjct: 173 NFGSRGRSRSKSLQKRSKSIGKSQSSSPQKQTSSGTKSRSHGRHSDSIARSPCKSPK 229 >gi|20127499 arginine/serine-rich splicing factor 6 [Homo sapiens] Length = 344 Score = 103 bits (258), Expect = 9e-23 Identities = 94/223 (42%), Positives = 115/223 (51%), Gaps = 39/223 (17%) Query: 8 PDVEGMTSLKVDNLTYRTSPDTLRRVFEKYGRV--GDVYIPRDRYTKESRGFAFVRFHDK 65 P V L V+NL+ R S L+ + G V D + KE + F Sbjct: 104 PPVRTEYRLIVENLSSRCSWQDLKDFMRQAGEVTYADAH-------KERTNEGVIEFRSY 156 Query: 66 RDAEDAMDAMDGAVLDGRELRVQMARYGRPPDSHHSRRGPPPRRYGGGGYGRRSRSPRRR 125 D + A+D +DG ++GR +R+ +P SH R Y G RSRS R R Sbjct: 157 SDMKRALDKLDGTEINGRNIRLIE---DKPRTSHR-------RSYSGS----RSRS-RSR 201 Query: 126 RRSRSRSRSRSRSRSRS-RYSRSKSRSRTRSRSRSTSKSRSAR-RSKSK------SSSVS 177 RRSRSRSR SRSRSRS SRS+SRSR++ RSRS SK R +R +SKSK S S S Sbjct: 202 RRSRSRSRRSSRSRSRSISKSRSRSRSRSKGRSRSRSKGRKSRSKSKSKPKSDRGSHSHS 261 Query: 178 RSRS-------RSRSRSRSRSPPPVSKRESKSRSRSKSPPKSP 213 RSRS RSRSRSRS +SKSRSRS+S SP Sbjct: 262 RSRSKDEYEKSRSRSRSRSPKENGKGDIKSKSRSRSQSRSNSP 304 Score = 71.6 bits (174), Expect = 5e-13 Identities = 76/251 (30%), Positives = 101/251 (40%), Gaps = 66/251 (26%) Query: 13 MTSLKVDNLTYRTSPDTLRRVFEKYGRVGDVYIPRDRYTKESRGFAFVRFHDKRDAEDAM 72 M + + L+Y ++R F YGR+ +V + G+ FV F D RDA+DA+ Sbjct: 1 MPRVYIGRLSYNVREKDIQRFFSGYGRLLEVDL--------KNGYGFVEFEDSRDADDAV 52 Query: 73 DAMDGAVLDGRELRVQMARYGRPPDSHHSRRGPPPRRYGGGGYGRRSRSPRRRRRSRSRS 132 ++G L G + V+ AR R +S R GGGGY R S R + R+ Sbjct: 53 YELNGKELCGERVIVEHARGPRRDRDGYSYGS----RSGGGGYSSRRTSGRDKYGPPVRT 108 Query: 133 RSR---SRSRSRSRYSRSKS--------------RSRTRS-----RSRSTSK-------- 162 R SR + K + RT RS S K Sbjct: 109 EYRLIVENLSSRCSWQDLKDFMRQAGEVTYADAHKERTNEGVIEFRSYSDMKRALDKLDG 168 Query: 163 ---------------------SRSARRSKSKSSSVSRSRSRSRSRSRSRSPPPVSKRESK 201 S S RS+S+S SRSRSR SRSRSRS +SK S+ Sbjct: 169 TEINGRNIRLIEDKPRTSHRRSYSGSRSRSRSRRRSRSRSRRSSRSRSRS---ISKSRSR 225 Query: 202 SRSRSKSPPKS 212 SRSRSK +S Sbjct: 226 SRSRSKGRSRS 236 Score = 53.9 bits (128), Expect = 1e-07 Identities = 37/87 (42%), Positives = 47/87 (54%), Gaps = 4/87 (4%) Query: 98 SHHSRRGPPPRRYGGGGYGRRSRSPRRRRRSRSRSRSRSRSRSRSR----YSRSKSRSRT 153 SH R Y RSRSP+ + +S+SRSRS+SRS SK+RS + Sbjct: 257 SHSHSRSRSKDEYEKSRSRSRSRSPKENGKGDIKSKSRSRSQSRSNSPLPVPPSKARSVS 316 Query: 154 RSRSRSTSKSRSARRSKSKSSSVSRSR 180 R+TS+SRS RSKS+S S S SR Sbjct: 317 PPPKRATSRSRSRSRSKSRSRSRSSSR 343 >gi|5730079 FUS interacting protein (serine-arginine rich) 1 isoform 1 [Homo sapiens] Length = 183 Score = 100 bits (250), Expect = 8e-22 Identities = 73/193 (37%), Positives = 97/193 (50%), Gaps = 32/193 (16%) Query: 3 YGRPPPDVEGMTSLKVDNLTYRTSPDTLRRVFEKYGRVGDVYIPRDRYTKESRGFAFVRF 62 Y RPP TSL V N+ T + LRR F +YG + DVY+P D YT+ RGFA+V+F Sbjct: 4 YLRPPN-----TSLFVRNVADDTRSEDLRREFGRYGPIVDVYVPLDFYTRRPRGFAYVQF 58 Query: 63 HDKRDAEDAMDAMDGAVLDGRELRVQMARYGRPPDSHHSRRGPPPRRYGGGGYGRRSRSP 122 D RDAEDA+ +D + GR++ +Q A+ R ++P Sbjct: 59 EDVRDAEDALHNLDRKWICGRQIEIQFAQGDR-------------------------KTP 93 Query: 123 RRRRRSRSRS-RSRSRSRSRSRYSRSKSRSRTRSRSRSTSKSRSARRSKSKSSSVSRSRS 181 + + R+ S SR RY RS+SRS R RSRS S + RRS S +S R Sbjct: 94 NQMKAKEGRNVYSSSRYDDYDRYRRSRSRSYERRRSRSRSFDYNYRRSYSPRNSRPTGRP 153 Query: 182 RSRSRSRSRSPPP 194 R RSRS S + P Sbjct: 154 R-RSRSHSDNDRP 165 >gi|169161980 PREDICTED: similar to FUS interacting protein (serine-arginine rich) 1, partial [Homo sapiens] Length = 181 Score = 99.4 bits (246), Expect = 2e-21 Identities = 74/183 (40%), Positives = 98/183 (53%), Gaps = 11/183 (6%) Query: 3 YGRPPPDVEGMTSLKVDNLTYRTSPDTLRRVFEKYGRVGDVYIPRDRYTKESRGFAFVRF 62 Y RPP TSL V N+ T + LRR F +YG + DVY+P D YT+ RGFA+V+F Sbjct: 4 YLRPPN-----TSLFVRNVADDTRSEDLRREFGRYGPIVDVYVPLDFYTRRPRGFAYVQF 58 Query: 63 HDKRDAEDAMDAMDGAVLDGRELRVQMARYGR-PPDSHHSRRGP---PPRRYGGGGYGRR 118 D RDAEDA+ +D + GR++ +Q A+ R P+ ++ G RY RR Sbjct: 59 EDVRDAEDALHNLDRKWICGRQIEIQFAQGDRKTPNQMKAKEGRNVYSSSRYDDYDRYRR 118 Query: 119 SRS-PRRRRRSRSRSRSRSRSRSRSRYSRSKSRSRTRSRSRSTSKSRSARRSKSKSSSVS 177 SRS RRRSRSRS + RS S +R R R RSRS S + + + SS+ Sbjct: 119 SRSRSYERRRSRSRSFDYNYRRSYSPRNRPTGRPR-RSRSHSDNDRPNCSWNTQYSSAYY 177 Query: 178 RSR 180 SR Sbjct: 178 TSR 180 >gi|29568103 U1 small nuclear ribonucleoprotein 70 kDa [Homo sapiens] Length = 437 Score = 97.8 bits (242), Expect = 6e-21 Identities = 75/226 (33%), Positives = 108/226 (47%), Gaps = 30/226 (13%) Query: 8 PDVEG--MTSLKVDNLTYRTSPDTLRRVFEKYGRVGDVYIPRDRYTKESRGFAFVRFHDK 65 P+ +G +L V + Y T+ LRR FE YG + +++ + + + RG+AF+ + + Sbjct: 95 PNAQGDAFKTLFVARVNYDTTESKLRREFEVYGPIKRIHMVYSKRSGKPRGYAFIEYEHE 154 Query: 66 RDAEDAMDAMDGAVLDGRELRVQMARYGRPPDSHHSRRGPPPRRYGGGGYGRR------- 118 RD A DG +DGR + V + R GR + +G PRR GGG G R Sbjct: 155 RDMHSAYKHADGKKIDGRRVLVDVER-GR------TVKGWRPRRLGGGLGGTRRGGADVN 207 Query: 119 ---------SRSPRRRRRSRSRSRSRSRSRSRSRYSRSKSRSRTRSRSRSTSKSRSARRS 169 SR R S R R R R R R RS+ R + R R RS S+ R RRS Sbjct: 208 IRHSGRDDTSRYDERPGPSPLPHRDRDRDRERERRERSRERDKERERRRSRSRDR-RRRS 266 Query: 170 KSKSSSVSRSRSRSRSRSRSRSPPPVSKRESKSRSRSKSPPKSPEE 215 +S+ R RSR RS+ + R +R S+SR R++ + EE Sbjct: 267 RSRDKE-ERRRSRERSKDKDRDR---KRRSSRSRERARRERERKEE 308 >gi|4506901 splicing factor, arginine/serine-rich 3 [Homo sapiens] Length = 164 Score = 95.9 bits (237), Expect = 2e-20 Identities = 72/171 (42%), Positives = 90/171 (52%), Gaps = 21/171 (12%) Query: 18 VDNLTYRTSPDTLRRVFEKYGRVGDVYIPRDRYTKESRGFAFVRFHDKRDAEDAMDAMDG 77 V NL + L R F YG + V++ R+ GFAFV F D RDA DA+ +DG Sbjct: 14 VGNLGNNGNKTELERAFGYYGPLRSVWVARN-----PPGFAFVEFEDPRDAADAVRELDG 68 Query: 78 AVLDGRELRVQMARYGRPPDSHHSRRGPPPRRYGGGGYGRRSRSPRRRRRSRSRSRSRSR 137 L G +RV+++ + RGPPP +GRR R RRR R RS R Sbjct: 69 RTLCGCRVRVELSN----GEKRSRNRGPPP------SWGRRPRDDYRRRSPPPRRRS-PR 117 Query: 138 SRSRSRYSRSKSRSRTRSRSRSTSKSRSARRSKSKSSSVSRSRSRSRSRSR 188 RS SR SRS+S SR R R RS S+ R+ + S+S SRSRSRSRS R Sbjct: 118 RRSFSR-SRSRSLSRDRRRERSLSRERNHKPSRS----FSRSRSRSRSNER 163 >gi|21361282 splicing factor, arginine/serine-rich 4 [Homo sapiens] Length = 494 Score = 95.1 bits (235), Expect = 4e-20 Identities = 81/234 (34%), Positives = 118/234 (50%), Gaps = 27/234 (11%) Query: 3 YGRPPPDVEGMTSLKVDNLTYRTSPDTLRRVFEKYGRVGDVYIPRDRYTKESRGFAFVRF 62 YG PP E L V+NL+ R S L+ + G V Y + K FV + Sbjct: 96 YG-PPTRTE--YRLIVENLSSRCSWQDLKDYMRQAGEV--TYADAHKGRKNEGVIEFVSY 150 Query: 63 HDKRDAEDAMDAMDGAVLDGRELRVQMARYGRPPDSHHSRRGPPPRRYGGGGYGRRSRS- 121 D + A ++ +DG ++GR++R+ + G +SR R + R+SRS Sbjct: 151 SDMKRA---LEKLDGTEVNGRKIRLVEDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSR 207 Query: 122 ------------PRRRRRSRSRSRSRSRSRSRSRYSRSKSRSRTRSRSRSTSKSRSARRS 169 R R SRSRS+SRSRS+SRSR + KSRS ++ +SRS S S RS Sbjct: 208 SGSSKSSHSKSRSRSRSGSRSRSKSRSRSQSRSRSKKEKSRSPSKEKSRSRSHSAGKSRS 267 Query: 170 KSKSSSVSRSRSRSR-SRSRSRSPPPVSKRESKSRSRSKSPPKSPEEE--GAVS 220 KSK + + ++ + +SRSP S+ +SKS+SRS+S + EEE G+VS Sbjct: 268 KSKDQAEEKIQNNDNVGKPKSRSP---SRHKSKSKSRSRSQERRVEEEKRGSVS 318 Score = 75.9 bits (185), Expect = 3e-14 Identities = 76/257 (29%), Positives = 109/257 (42%), Gaps = 64/257 (24%) Query: 13 MTSLKVDNLTYRTSPDTLRRVFEKYGRVGDVYIPRDRYTKESRGFAFVRFHDKRDAEDAM 72 M + + L+Y+ + R F+ YG++ +V + G+ FV F D RDA+DA+ Sbjct: 1 MPRVYIGRLSYQARERDVERFFKGYGKILEVDL--------KNGYGFVEFDDLRDADDAV 52 Query: 73 DAMDGAVLDGRELRVQMARYGRPPDSHHSRR-------------GPPPR----------- 108 ++G L G + V+ AR R S+ S R GPP R Sbjct: 53 YELNGKDLCGERVIVEHARGPRRDGSYGSGRSGYGYRRSGRDKYGPPTRTEYRLIVENLS 112 Query: 109 ------------------RYGGGGYGRR--------SRSPRRRRRSRSRSRSRSRSRSRS 142 Y GR+ S S +R + + + R Sbjct: 113 SRCSWQDLKDYMRQAGEVTYADAHKGRKNEGVIEFVSYSDMKRALEKLDGTEVNGRKIRL 172 Query: 143 RYSRSKSRSR---TRSRSRSTSKSRSARRSKSKSSSVSRSRSRSRSRSRSRSPPPVSKRE 199 + SR R +RSRS S S+SRS KS+S S S S S+SRSRSRS S+ Sbjct: 173 VEDKPGSRRRRSYSRSRSHSRSRSRSRHSRKSRSRSGSSKSSHSKSRSRSRSG---SRSR 229 Query: 200 SKSRSRSKSPPKSPEEE 216 SKSRSRS+S +S +E+ Sbjct: 230 SKSRSRSQSRSRSKKEK 246 Score = 75.1 bits (183), Expect = 4e-14 Identities = 49/119 (41%), Positives = 62/119 (52%), Gaps = 6/119 (5%) Query: 98 SHHSRRGPPPRRYGGGGYGRRSRSPRRRRRSRSRSRSRSRSRSRSRYSRSKSRSRTRSRS 157 S R + G GR R+ RSRSRS+ SRSRSRSR S+SK + + R RS Sbjct: 302 SRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSR-SKSKDKRKGRKRS 360 Query: 158 RSTSKSRSARRSKSKSSSVSRSRSRSRSRSRSRSPPPVSKRESKSRSRSKSPPKSPEEE 216 R S+SRS RSKS+ RSR R R K+E RS+S+SP +S +E Sbjct: 361 REESRSRSRSRSKSE-----RSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKE 414 Score = 71.2 bits (173), Expect = 6e-13 Identities = 52/124 (41%), Positives = 68/124 (54%), Gaps = 18/124 (14%) Query: 98 SHHSRRGPPPRRYGGGGYGRRSRSPRRRRRSRSRSRSRSRSRSRSRYSRSKSRSR----- 152 S SR+ R G ++ + R +SRS SRS S+ R ++ S+ R Sbjct: 374 SERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSESSQREGRGESEN 433 Query: 153 ------TRSRSRSTSKSR----SARRSKSKSSSVSRSRSRSRSRSRSRSPPPVSKRESKS 202 TRSRSRS SKS+ S RS+SKS+S +RSRS+SRSRS SRSP S+ S+S Sbjct: 434 AGTNQETRSRSRSNSKSKPNLPSESRSRSKSASKTRSRSKSRSRSASRSP---SRSRSRS 490 Query: 203 RSRS 206 SRS Sbjct: 491 HSRS 494 Score = 70.9 bits (172), Expect = 8e-13 Identities = 54/113 (47%), Positives = 68/113 (60%), Gaps = 15/113 (13%) Query: 118 RSRSPRRRRRSRSRSRSRSRSR-----SRSRYSRSKSR------SRTRSRSRSTSKSRSA 166 +SRSP R + S+S+SRSRS+ R R SR +S+ SR+RSRS+ S+SRS Sbjct: 287 KSRSPSRHK-SKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSR 345 Query: 167 RRSKSKSSSVSRSRSR--SRSRSRSRSPPPVS-KRESKSRSRSKSPPKSPEEE 216 RSKSK R RSR SRSRSRSRS S KR SK S++ S K +E+ Sbjct: 346 SRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKED 398 Score = 67.4 bits (163), Expect = 9e-12 Identities = 63/174 (36%), Positives = 78/174 (44%), Gaps = 44/174 (25%) Query: 83 RELRVQMARYG---RPPDSHHSRRGPPPRRYGGGGYGRRSRSPRR---RRRSRSRSRSRS 136 +E RV+ + G R S R R GG RSRS + +R+ R RSR S Sbjct: 305 QERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREES 364 Query: 137 RSRSRSRYSRSKSRSR-------------------TRSRSRSTSKSRSARRSKSKSSSVS 177 RSRSRSR +SR R RS+SRS S+S S R +KS S Sbjct: 365 RSRSRSRSKSERSRKRGSKRDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSESSQ 424 Query: 178 R------------SRSRSRSRSRSRSPPPV-------SKRESKSRSRSKSPPKS 212 R +RSRSRS S+S P + SK SK+RSRSKS +S Sbjct: 425 REGRGESENAGTNQETRSRSRSNSKSKPNLPSESRSRSKSASKTRSRSKSRSRS 478 Score = 66.2 bits (160), Expect = 2e-11 Identities = 43/102 (42%), Positives = 63/102 (61%), Gaps = 10/102 (9%) Query: 122 PRRRRRSRSRSRSRSRSRSRSRYSRSKSR---SRTRSRSRSTSKSRSARRSK--SKSSSV 176 P+ R SR +S+S+SRSRS+ R + R SR RS+ +S +SRS RSK S+S S Sbjct: 286 PKSRSPSRHKSKSKSRSRSQERRVEEEKRGSVSRGRSQEKSLRQSRSRSRSKGGSRSRSR 345 Query: 177 SRSRSRSRSRSRSRSPPPVSKRESKSRSRSKSPPKSPEEEGA 218 SRS+S+ + + R R S+ ES+SRSRS+S + + G+ Sbjct: 346 SRSKSKDKRKGRKR-----SREESRSRSRSRSKSERSRKRGS 382 Score = 65.9 bits (159), Expect = 3e-11 Identities = 43/105 (40%), Positives = 60/105 (57%), Gaps = 7/105 (6%) Query: 117 RRSRSPRRRR---RSRSRSRSRSRSRSRSR-YSRSKSRSRTRSRSRSTSKSRSARRSKSK 172 R+SRS R + RSRSRSRS+S+ + + R SR +SRSR+RSRS+S + + SK Sbjct: 328 RQSRSRSRSKGGSRSRSRSRSKSKDKRKGRKRSREESRSRSRSRSKSERSRKRGSKRDSK 387 Query: 173 SSSVSRSRSRSRSRSRSRSPPPVSKRESKSRSRSKSPPKSPEEEG 217 + S + + RS+SRSP S+ SK R +KS E G Sbjct: 388 AGSSKKKKKEDTDRSQSRSP---SRSVSKEREHAKSESSQREGRG 429 Score = 62.0 bits (149), Expect = 4e-10 Identities = 45/110 (40%), Positives = 60/110 (54%), Gaps = 2/110 (1%) Query: 83 RELRVQMARYGRPPDSHHSRRGPPPRRYGGGGYGRRSRSPRRRRRSRSRSRSRSR-SRSR 141 R+ + ++ + D+ S+ P R +S S +R R S + ++ +RSR Sbjct: 384 RDSKAGSSKKKKKEDTDRSQSRSPSRSVSKEREHAKSESSQREGRGESENAGTNQETRSR 443 Query: 142 SRYSRSKSRSRTRSRSRSTSKSRSARRSKSKSSSVSRSRSRSRSRSRSRS 191 SR S SKS+ S SRS SKS S RS+SKS S S SRS SRSRSRS S Sbjct: 444 SR-SNSKSKPNLPSESRSRSKSASKTRSRSKSRSRSASRSPSRSRSRSHS 492 >gi|86991440 splicing factor, arginine/serine-rich 5 [Homo sapiens] Length = 272 Score = 94.4 bits (233), Expect = 7e-20 Identities = 76/204 (37%), Positives = 103/204 (50%), Gaps = 35/204 (17%) Query: 5 RPPPDVEGMTSLKVDNLTYRTSPDTLRRVFEKYGRVGDVYIPRDRYTKESRGFAFVRFHD 64 R P V L V+NL+ R S L+ + G V R + + V F Sbjct: 99 RNAPPVRTENRLIVENLSSRVSWQDLKDFMRQAGEVTFADAHRPKLNE-----GVVEFAS 153 Query: 65 KRDAEDAMDAMDGAVLDGRELRVQMARYGRPPDSHHSRRGPPPRRYGGGGYGRRSRSPRR 124 D ++A++ + G ++GR++++ HSR RSRS R Sbjct: 154 YGDLKNAIEKLSGKEINGRKIKLIEG------SKRHSRS--------------RSRS-RS 192 Query: 125 RRRSRSRSRSRSRSRSRSRYSRSKSRSRTRSRSRSTSKSRSARRSKSKSSSVSRSRSRSR 184 R RS SRSRSRSRSRSR YSRS+SRSR+RSRS+S S SRS KS+ + Sbjct: 193 RTRSSSRSRSRSRSRSRKSYSRSRSRSRSRSRSKSRSVSRSPVPEKSQ---------KRG 243 Query: 185 SRSRSRSPPPVSKRESKSRSRSKS 208 S SRS+SP V ++ S+SRSRS+S Sbjct: 244 SSSRSKSPASVDRQRSRSRSRSRS 267 Score = 71.2 bits (173), Expect = 6e-13 Identities = 74/236 (31%), Positives = 103/236 (43%), Gaps = 54/236 (22%) Query: 30 LRRVFEKYGRVGDVYIPRDRYTKESRGFAFVRFHDKRDAEDAMDAMDGAVLDGRELRVQM 89 + R F+ YGR+ D+ + RGF FV F D RDA+DA+ +DG L + ++ Sbjct: 20 VERFFKGYGRIRDIDL--------KRGFGFVEFEDPRDADDAVYELDGKELCSERVTIEH 71 Query: 90 ARY--------GRPPDSHHSRR-------GPPPR-----------------------RYG 111 AR GR D SRR PP R R Sbjct: 72 ARARSRGGRGRGRYSDRFSSRRPRNDRRNAPPVRTENRLIVENLSSRVSWQDLKDFMRQA 131 Query: 112 GGGYGRRSRSPRRRR---RSRSRSRSRSRSRSRSRYSRSKSRSRTRSRSRSTSKSRSARR 168 G + P+ S ++ S + + + S+ S+SRS R Sbjct: 132 GEVTFADAHRPKLNEGVVEFASYGDLKNAIEKLSGKEINGRKIKLIEGSKRHSRSRSRSR 191 Query: 169 SKSKSSSVSRSRSRSRSR---SRSRSPPPVSKRESKSRSRSKSP-PKSPEEEGAVS 220 S+++SSS SRSRSRSRSR SRSRS S+ SKSRS S+SP P+ ++ G+ S Sbjct: 192 SRTRSSSRSRSRSRSRSRKSYSRSRSRSR-SRSRSKSRSVSRSPVPEKSQKRGSSS 246 >gi|86991438 splicing factor, arginine/serine-rich 5 [Homo sapiens] Length = 272 Score = 94.4 bits (233), Expect = 7e-20 Identities = 76/204 (37%), Positives = 103/204 (50%), Gaps = 35/204 (17%) Query: 5 RPPPDVEGMTSLKVDNLTYRTSPDTLRRVFEKYGRVGDVYIPRDRYTKESRGFAFVRFHD 64 R P V L V+NL+ R S L+ + G V R + + V F Sbjct: 99 RNAPPVRTENRLIVENLSSRVSWQDLKDFMRQAGEVTFADAHRPKLNE-----GVVEFAS 153 Query: 65 KRDAEDAMDAMDGAVLDGRELRVQMARYGRPPDSHHSRRGPPPRRYGGGGYGRRSRSPRR 124 D ++A++ + G ++GR++++ HSR RSRS R Sbjct: 154 YGDLKNAIEKLSGKEINGRKIKLIEG------SKRHSRS--------------RSRS-RS 192 Query: 125 RRRSRSRSRSRSRSRSRSRYSRSKSRSRTRSRSRSTSKSRSARRSKSKSSSVSRSRSRSR 184 R RS SRSRSRSRSRSR YSRS+SRSR+RSRS+S S SRS KS+ + Sbjct: 193 RTRSSSRSRSRSRSRSRKSYSRSRSRSRSRSRSKSRSVSRSPVPEKSQ---------KRG 243 Query: 185 SRSRSRSPPPVSKRESKSRSRSKS 208 S SRS+SP V ++ S+SRSRS+S Sbjct: 244 SSSRSKSPASVDRQRSRSRSRSRS 267 Score = 71.2 bits (173), Expect = 6e-13 Identities = 74/236 (31%), Positives = 103/236 (43%), Gaps = 54/236 (22%) Query: 30 LRRVFEKYGRVGDVYIPRDRYTKESRGFAFVRFHDKRDAEDAMDAMDGAVLDGRELRVQM 89 + R F+ YGR+ D+ + RGF FV F D RDA+DA+ +DG L + ++ Sbjct: 20 VERFFKGYGRIRDIDL--------KRGFGFVEFEDPRDADDAVYELDGKELCSERVTIEH 71 Query: 90 ARY--------GRPPDSHHSRR-------GPPPR-----------------------RYG 111 AR GR D SRR PP R R Sbjct: 72 ARARSRGGRGRGRYSDRFSSRRPRNDRRNAPPVRTENRLIVENLSSRVSWQDLKDFMRQA 131 Query: 112 GGGYGRRSRSPRRRR---RSRSRSRSRSRSRSRSRYSRSKSRSRTRSRSRSTSKSRSARR 168 G + P+ S ++ S + + + S+ S+SRS R Sbjct: 132 GEVTFADAHRPKLNEGVVEFASYGDLKNAIEKLSGKEINGRKIKLIEGSKRHSRSRSRSR 191 Query: 169 SKSKSSSVSRSRSRSRSR---SRSRSPPPVSKRESKSRSRSKSP-PKSPEEEGAVS 220 S+++SSS SRSRSRSRSR SRSRS S+ SKSRS S+SP P+ ++ G+ S Sbjct: 192 SRTRSSSRSRSRSRSRSRKSYSRSRSRSR-SRSRSKSRSVSRSPVPEKSQKRGSSS 246 >gi|133922600 splicing factor, arginine/serine-rich 16 [Homo sapiens] Length = 674 Score = 85.9 bits (211), Expect = 3e-17 Identities = 74/154 (48%), Positives = 83/154 (53%), Gaps = 33/154 (21%) Query: 94 RPPDSHHSRRGPPPRRYGGGGY--GRRSRSPRRRRRSRSRSRSRSRSRSRSR-------- 143 R S S R R GGG Y GR +RS R R SRSRSRSR SRSRSR Sbjct: 388 RTSSSRSSSRSSSRSRRGGGYYRSGRHARS-RSRSWSRSRSRSRRYSRSRSRGRRHSGGG 446 Query: 144 ------YSRSKSRS-----RTRSRSRSTSKSRSAR---------RSKSKSS-SVSRSRSR 182 YSRS +R R RSRSRS S R R S+S+SS S+S SRSR Sbjct: 447 SRDGHRYSRSPARRGGYGPRRRSRSRSHSGDRYRRGGRGLRHHSSSRSRSSWSLSPSRSR 506 Query: 183 SRSRSRSRSPPPVSKRESKSRSRSKSPPKSPEEE 216 S +RSRS SP P S+ S+SRSRS+SP SP E Sbjct: 507 SLTRSRSHSPSP-SQSRSRSRSRSQSPSPSPARE 539 Score = 68.9 bits (167), Expect = 3e-12 Identities = 59/146 (40%), Positives = 69/146 (47%), Gaps = 43/146 (29%) Query: 93 GRPPDSHHSRRGPPPRRYGGGGYGRRSRSPRRRRRSRSRS-----------RSRSRSRSR 141 G D H R P R GGYG PRRR RSRS S R S SRSR Sbjct: 445 GGSRDGHRYSRSPARR----GGYG-----PRRRSRSRSHSGDRYRRGGRGLRHHSSSRSR 495 Query: 142 SRYSRSKSRSRTRSRSRSTSKSRSARRSKSKSSSVSRSRSRSRSRSRSRSPPPVSKRESK 201 S +S S SRSR+ +RSR S S S S+SRSRSRSRS+SP P RE Sbjct: 496 SSWSLSPSRSRSLTRSR--------------SHSPSPSQSRSRSRSRSQSPSPSPAREKL 541 Query: 202 SRSRS---------KSPPKSPEEEGA 218 +R + K+ P + +E GA Sbjct: 542 TRPAASPAVGEKLKKTEPAAGKETGA 567 Score = 62.0 bits (149), Expect = 4e-10 Identities = 50/106 (47%), Positives = 59/106 (55%), Gaps = 10/106 (9%) Query: 105 PPPRRYGGGGYGRRSRSPRRRRRSRSRSRSRSRSRSRSRYSRSKSRSRTRSRSRSTSKSR 164 P P + GG GR + + RRRS S S S S SR+ S SRS SRS +RSR R R Sbjct: 357 PAPPQPGGPAPGRNASA---RRRSSSSSSSSSASRTSS--SRSSSRSSSRSR-RGGGYYR 410 Query: 165 SARRSKSKSSSVSRSRSRS----RSRSRSRSPPPVSKRESKSRSRS 206 S R ++S+S S SRSRSRS RSRSR R R+ SRS Sbjct: 411 SGRHARSRSRSWSRSRSRSRRYSRSRSRGRRHSGGGSRDGHRYSRS 456 Score = 56.6 bits (135), Expect = 2e-08 Identities = 45/96 (46%), Positives = 49/96 (51%), Gaps = 2/96 (2%) Query: 77 GAVLDGRELRVQMARYGRPPDSHHSR-RGPPPRRYGGGGYGRRSRSPRRRRRSRSRSRSR 135 G DG AR G SR R RY GG G R S R R S S S SR Sbjct: 445 GGSRDGHRYSRSPARRGGYGPRRRSRSRSHSGDRYRRGGRGLRHHSSSRSRSSWSLSPSR 504 Query: 136 SRSRSRSR-YSRSKSRSRTRSRSRSTSKSRSARRSK 170 SRS +RSR +S S S+SR+RSRSRS S S S R K Sbjct: 505 SRSLTRSRSHSPSPSQSRSRSRSRSQSPSPSPAREK 540 Score = 40.4 bits (93), Expect = 0.001 Identities = 45/185 (24%), Positives = 74/185 (40%), Gaps = 13/185 (7%) Query: 24 RTSPDTLRRVFEKYGRVGDVYIPRDRYTKESRGFAFVRFHDKRDAEDAMDAMDGAVLDGR 83 R S D +++ EK +G Y D E A ++ AE+ ++ + V+ Sbjct: 147 RPSEDEKKKLAEKKASIGYTY--EDSTVAEVEKAAEKPEEEESAAEEESNSDEDEVIPDI 204 Query: 84 ELRVQMARYGRPPDSHHSRRGPPPRRYG--GGGYGRRSRSPRRRRRSRSRSRSRSRSRS- 140 ++ V + + + +++ YG G + R R + + +++ ++ Sbjct: 205 DVEVDVDELNQEQVADLNKQATT---YGMADGDFVRMLRKDKEEAEAIKHAKALEEEKAM 261 Query: 141 ----RSRYSRSKSRSRTRSRSRSTSKSRSARRSKSKSSSVSRSRSRSRSRSRSRSPPPVS 196 RSR R + R + R R R S ARR RS S S S SRSRS P Sbjct: 262 YSGRRSRRQRREFREK-RLRGRKISPPSYARRDSPTYDPYKRSPSESSSESRSRSRSPTP 320 Query: 197 KRESK 201 RE K Sbjct: 321 GREEK 325 Score = 40.0 bits (92), Expect = 0.002 Identities = 25/78 (32%), Positives = 39/78 (50%), Gaps = 1/78 (1%) Query: 117 RRSRSPRRRRRSRSRSRSRSRSRSRSRYSRSKSRSRTRSRSRSTSKSRSARRSKSKSSSV 176 +++ + ++ R R+ +R R K R R R + R + + +R+S+S S Sbjct: 594 KKAAQEKMIQQEHERQEREDELRAMARKIRMKERER-REKEREEWERQYSRQSRSPSPRY 652 Query: 177 SRSRSRSRSRSRSRSPPP 194 SR S SR RSRSRS P Sbjct: 653 SREYSSSRRRSRSRSRSP 670 Score = 34.7 bits (78), Expect = 0.066 Identities = 29/85 (34%), Positives = 40/85 (47%), Gaps = 18/85 (21%) Query: 63 HDKRDAEDAMDAMDGAVLDGRELRVQMARYGRPPDSHHSRRGPPPRRYGGGGYGRRSRSP 122 H++++ ED + AM R++R++ R R Y R+SRSP Sbjct: 606 HERQEREDELRAM------ARKIRMK-----------ERERREKEREEWERQYSRQSRSP 648 Query: 123 RRR-RRSRSRSRSRSRSRSRSRYSR 146 R R S SR RSRSRSRS + R Sbjct: 649 SPRYSREYSSSRRRSRSRSRSPHYR 673 Score = 33.9 bits (76), Expect = 0.11 Identities = 51/165 (30%), Positives = 58/165 (35%), Gaps = 69/165 (41%) Query: 116 GRRSRSPRRR-RRSRSRSRS------------------RSRSRSRSRYSRSKSRSRTRSR 156 GRRSR RR R R R R RS S S S SRS+SRS T R Sbjct: 264 GRRSRRQRREFREKRLRGRKISPPSYARRDSPTYDPYKRSPSESSSE-SRSRSRSPTPGR 322 Query: 157 SR-----------------------------------------STSKSRSARRSKSKSS- 174 + ++ SARR S SS Sbjct: 323 EEKITFITSFGGSDEEAAAAAAAAAASGVTTGKPPAPPQPGGPAPGRNASARRRSSSSSS 382 Query: 175 -------SVSRSRSRSRSRSRSRSPPPVSKRESKSRSRSKSPPKS 212 S SRS SRS SRSR S R ++SRSRS S +S Sbjct: 383 SSSASRTSSSRSSSRSSSRSRRGGGYYRSGRHARSRSRSWSRSRS 427 Score = 32.3 bits (72), Expect = 0.33 Identities = 25/89 (28%), Positives = 39/89 (43%), Gaps = 7/89 (7%) Query: 126 RRSRSRSRSRSRSRSRSRYSRSKSRSRTRSRSRSTSKSRSARRSKSKSSSVSRSRSRSRS 185 R+ ++ ++ + + R + R+ +R RR K + R S Sbjct: 588 RQFKADKKAAQEKMIQQEHERQEREDELRAMARKIRMKERERREKEREEW-----ERQYS 642 Query: 186 RSRSRSPPPVSKRE-SKSRSRSKSPPKSP 213 R +SRSP P RE S SR RS+S +SP Sbjct: 643 R-QSRSPSPRYSREYSSSRRRSRSRSRSP 670 Score = 29.3 bits (64), Expect = 2.8 Identities = 21/102 (20%), Positives = 42/102 (41%), Gaps = 3/102 (2%) Query: 118 RSRSP---RRRRRSRSRSRSRSRSRSRSRYSRSKSRSRTRSRSRSTSKSRSARRSKSKSS 174 RS SP + R RSRSRS+S S S +R + +R + + + T + +K Sbjct: 512 RSHSPSPSQSRSRSRSRSQSPSPSPAREKLTRPAASPAVGEKLKKTEPAAGKETGAAKPK 571 Query: 175 SVSRSRSRSRSRSRSRSPPPVSKRESKSRSRSKSPPKSPEEE 216 + + + R + K+ ++ + + + E+ Sbjct: 572 LTPQEKLKLRMQKALNRQFKADKKAAQEKMIQQEHERQERED 613 Score = 28.5 bits (62), Expect = 4.7 Identities = 22/67 (32%), Positives = 30/67 (44%), Gaps = 19/67 (28%) Query: 165 SARRSKSKSSSVSRSRSRSRSRSRSRSPPPVSKRE---------------SKSRSRSKSP 209 S RRS+ + R R R R SPP ++R+ S+SRSRS+SP Sbjct: 263 SGRRSRRQR----REFREKRLRGRKISPPSYARRDSPTYDPYKRSPSESSSESRSRSRSP 318 Query: 210 PKSPEEE 216 EE+ Sbjct: 319 TPGREEK 325 >gi|4502847 cold inducible RNA binding protein [Homo sapiens] Length = 172 Score = 85.5 bits (210), Expect = 3e-17 Identities = 62/162 (38%), Positives = 83/162 (51%), Gaps = 15/162 (9%) Query: 16 LKVDNLTYRTSPDTLRRVFEKYGRVGDVYIPRDRYTKESRGFAFVRFHDKRDAEDAMDAM 75 L V L++ T+ +L +VF KYG++ +V + +DR T+ SRGF FV F + DA+DAM AM Sbjct: 8 LFVGGLSFDTNEQSLEQVFSKYGQISEVVVVKDRETQRSRGFGFVTFENIDDAKDAMMAM 67 Query: 76 DGAVLDGRELRVQMARYGRPPDSHHSRRGPPPRRYGGGGYGRRSRSPRRRRRSRSRSRSR 135 +G +DGR++RV A G+ D+ R Y GG G R R R R R Sbjct: 68 NGKSVDGRQIRVDQA--GKSSDNR-------SRGYRGGSAGGRGFF----RGGRGRGRGF 114 Query: 136 SRSRSRSRY--SRSKSRSRTRSRSRSTSKSRSARRSKSKSSS 175 SR Y +R +SRS SR SRS S SS Sbjct: 115 SRGGGDRGYGGNRFESRSGGYGGSRDYYSSRSQSGGYSDRSS 156 >gi|119226260 calcium homeostasis endoplasmic reticulum protein [Homo sapiens] Length = 916 Score = 85.1 bits (209), Expect = 4e-17 Identities = 57/102 (55%), Positives = 68/102 (66%), Gaps = 9/102 (8%) Query: 114 GYGRRSRSPRRRRRSRSRSRSRSRSRSRSRYSRSK---SRSRTRSRSRSTSKSRSARRSK 170 G +R+ P R R SRS+SR RS SRS SR S+S SRSR+RS SRS S+SRS RS+ Sbjct: 728 GQEKRNSGPSRSR-SRSKSRGRSSSRSNSRSSKSSGSYSRSRSRSCSRSYSRSRSRSRSR 786 Query: 171 SKSSSVSRSRSRSRSRSRSRSPPPVSKRESKSRSRSKSPPKS 212 S+SS RSRSRS+SRSRS R +SRSRS +PP S Sbjct: 787 SRSS-----RSRSRSQSRSRSKSYSPGRRRRSRSRSPTPPSS 823 Score = 81.3 bits (199), Expect = 6e-16 Identities = 53/115 (46%), Positives = 67/115 (58%), Gaps = 3/115 (2%) Query: 95 PPDSHHSRRGPPPRRYGGGGYGRRSRSPRRRRRSRSRSRSRSRSRSRSRYSRSKSRSRTR 154 PP R + G + R RRR+ R+ SRSRSRS+ S+ RS +R Sbjct: 696 PPSHDRPRNSEGWEQNGLYEFFRAKMRARRRKGQEKRNSGPSRSRSRSK---SRGRSSSR 752 Query: 155 SRSRSTSKSRSARRSKSKSSSVSRSRSRSRSRSRSRSPPPVSKRESKSRSRSKSP 209 S SRS+ S S RS+S+S S S SRSRSRSRSRSRS S+ +S+SRS+S SP Sbjct: 753 SNSRSSKSSGSYSRSRSRSCSRSYSRSRSRSRSRSRSSRSRSRSQSRSRSKSYSP 807 Score = 79.7 bits (195), Expect = 2e-15 Identities = 58/111 (52%), Positives = 66/111 (59%), Gaps = 11/111 (9%) Query: 117 RRSRSPRRRRRSRSRSRSRSRSRSRSR-----YSRSKSRSRTRSRSRSTSKSRS-ARRSK 170 R S R R RS+SR RS SRS SRS YSRS+SRS +RS SRS S+SRS +R S+ Sbjct: 732 RNSGPSRSRSRSKSRGRSSSRSNSRSSKSSGSYSRSRSRSCSRSYSRSRSRSRSRSRSSR 791 Query: 171 SKSSSVSRSRSRS-----RSRSRSRSPPPVSKRESKSRSRSKSPPKSPEEE 216 S+S S SRSRS+S R RSRSRSP P S S S P EE Sbjct: 792 SRSRSQSRSRSKSYSPGRRRRSRSRSPTPPSSAGLGSNSAPPIPDSRLGEE 842 Score = 42.0 bits (97), Expect = 4e-04 Identities = 27/53 (50%), Positives = 30/53 (56%) Query: 101 SRRGPPPRRYGGGGYGRRSRSPRRRRRSRSRSRSRSRSRSRSRYSRSKSRSRT 153 SR R Y RSRS R RSRS+SRSRS+S S R RS+SRS T Sbjct: 767 SRSRSCSRSYSRSRSRSRSRSRSSRSRSRSQSRSRSKSYSPGRRRRSRSRSPT 819 >gi|41327773 DEAD (Asp-Glu-Ala-Asp) box polypeptide 46 [Homo sapiens] Length = 1031 Score = 84.7 bits (208), Expect = 6e-17 Identities = 63/132 (47%), Positives = 74/132 (56%), Gaps = 15/132 (11%) Query: 81 DGRELRVQMARYGRPPDSHHSRRGPPPRRYGGGGYGRRSRS---PRRRRRSRSRSRSRSR 137 + R R + A GR SR P + G RRSRS RRR RSRSR + RSR Sbjct: 4 ESRHYRKRSASRGR--SGSRSRSRSPSDKRSKRGDDRRSRSRDRDRRRERSRSRDKRRSR 61 Query: 138 SRSRSRYSRSKSRSRTRSRSRSTSKSRSARRSKSKSSSVSRSRSRSRSRSRSRSPPPVSK 197 SR R R RS+SR R RSR R S+SR RR SRSRSR R RSRS SP SK Sbjct: 62 SRDRKRLRRSRSRERDRSRERRRSRSRDRRR--------SRSRSRGR-RSRSSSPGNKSK 112 Query: 198 R-ESKSRSRSKS 208 + E++SRS+ K+ Sbjct: 113 KTENRSRSKEKT 124 Score = 72.4 bits (176), Expect = 3e-13 Identities = 52/112 (46%), Positives = 61/112 (54%), Gaps = 13/112 (11%) Query: 116 GRRSRSPRRRRRSRSRSRSRSRSRSRS-----RYSRSKSRSRTRSRSRSTSKSRSARRSK 170 GR SR R+R SR RS SRSRSRS S R +SRSR R R R S+SR RRS+ Sbjct: 2 GRESRHYRKRSASRGRSGSRSRSRSPSDKRSKRGDDRRSRSRDRDRRRERSRSRDKRRSR 61 Query: 171 SKSSS-VSRSRSRSRSRSRSRSPPPVSKRESKSRSRSKSPPKSPEEEGAVSS 221 S+ + RSRSR R RSR R R S+SR R +S +S SS Sbjct: 62 SRDRKRLRRSRSRERDRSRER-------RRSRSRDRRRSRSRSRGRRSRSSS 106 Score = 70.9 bits (172), Expect = 8e-13 Identities = 51/124 (41%), Positives = 65/124 (52%), Gaps = 4/124 (3%) Query: 94 RPPDSHHSRRGPPPRRYGGGGYGRRSRSPRR-RRRSRSRSRSR-SRSRSRSRYSRSKSRS 151 R P S+RG R RR RS R +RRSRSR R R RSRSR R RS+ R Sbjct: 25 RSPSDKRSKRGDDRRSRSRDRDRRRERSRSRDKRRSRSRDRKRLRRSRSRER-DRSRERR 83 Query: 152 RTRSRSRSTSKSRS-ARRSKSKSSSVSRSRSRSRSRSRSRSPPPVSKRESKSRSRSKSPP 210 R+RSR R S+SRS RRS+S S ++ +RSRS+ ++ S +E K K Sbjct: 84 RSRSRDRRRSRSRSRGRRSRSSSPGNKSKKTENRSRSKEKTDGGESSKEKKKDKDDKEDE 143 Query: 211 KSPE 214 K + Sbjct: 144 KEKD 147 Score = 47.4 bits (111), Expect = 1e-05 Identities = 39/100 (39%), Positives = 51/100 (51%), Gaps = 8/100 (8%) Query: 117 RRSRSPRRRRRSRSRSRSRSRSRSRSRYSRSKSRSRTRSRSRSTSKSRSARRSKSKSSSV 176 RRSRS R RRRSRSRSR R RSRS S ++SK +T +RSRS K+ SK K Sbjct: 83 RRSRS-RDRRRSRSRSRGR-RSRSSSPGNKSK---KTENRSRSKEKTDGGESSKEKKKD- 136 Query: 177 SRSRSRSRSRSRSRSPPPVSKRESKSRSRSKSPPKSPEEE 216 + + + +K E + R R + K EE+ Sbjct: 137 --KDDKEDEKEKDAGNFDQNKLEEEMRKRKERVEKWREEQ 174 Score = 28.9 bits (63), Expect = 3.6 Identities = 23/102 (22%), Positives = 39/102 (38%), Gaps = 1/102 (0%) Query: 65 KRDAEDAMDAMDGAVLDGRELRVQMARYGRPPDSHHSRRGPPPRRYGGGGYGRRSRSPRR 124 +R+ + D D + LR +R R RR GRRSRS Sbjct: 48 RRERSRSRDKRRSRSRDRKRLRRSRSRERDRSRERRRSRSRDRRRSRSRSRGRRSRSSSP 107 Query: 125 RRRSRSRSRSRSRSRSRSRYSRSKSRSRTRSRSRSTSKSRSA 166 +S+ ++ +RSRS+ ++ S + + K + A Sbjct: 108 GNKSK-KTENRSRSKEKTDGGESSKEKKKDKDDKEDEKEKDA 148 >gi|6857826 RNA-binding protein S1, serine-rich domain [Homo sapiens] Length = 305 Score = 83.6 bits (205), Expect = 1e-16 Identities = 55/145 (37%), Positives = 78/145 (53%), Gaps = 8/145 (5%) Query: 14 TSLKVDNLTYRTSPDTLRRVFEKYGRVGDVYIPRDR-YTKESRGFAFVRFHDKRDAEDAM 72 T + + LT + D + +F YG++ + +P +R + S+G+A+V F + +AE A+ Sbjct: 161 TKVHIGRLTRNVTKDHIMEIFSTYGKIKMIDMPVERMHPHLSKGYAYVEFENPDEAEKAL 220 Query: 73 DAMDGAVLDGRELRVQ--MARYGRPPDSHHS---RRGPPPR--RYGGGGYGRRSRSPRRR 125 MDG +DG+E+ +A + RPP S R PPP R RRSRSPRRR Sbjct: 221 KHMDGGQIDGQEITATAVLAPWPRPPPRRFSPPRRMLPPPPMWRRSPPRMRRRSRSPRRR 280 Query: 126 RRSRSRSRSRSRSRSRSRYSRSKSR 150 R RSRS R R RSR S + SR Sbjct: 281 SPVRRRSRSPGRRRHRSRSSSNSSR 305 Score = 63.9 bits (154), Expect = 1e-10 Identities = 52/129 (40%), Positives = 66/129 (51%), Gaps = 13/129 (10%) Query: 101 SRRGPPP-RRYGGGGYGRRSRSPRRRRRSRSRSRSRSRSRSRSRYSRSKSRSRTRSRSRS 159 S R P P +R + RS + S + R R ++R R S S S TRSRS S Sbjct: 22 STRAPSPTKRKDRSDEKSKDRSKDKGATKESSEKDRGRDKTRKRRSASSGSSSTRSRSSS 81 Query: 160 TSKSRSARRS-----KSKSSSVSRSRSRSRSRSRSRS-----PPPVSKR-ESKSRSRSKS 208 TS S S+ + S SS+ SRS S S SRS S S P P +R +++ RSRSKS Sbjct: 82 TSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSSSGSPSPSRRRHDNRRRSRSKS 141 Query: 209 -PPKSPEEE 216 PPK E+E Sbjct: 142 KPPKRDEKE 150 Score = 61.2 bits (147), Expect = 7e-10 Identities = 46/105 (43%), Positives = 53/105 (50%), Gaps = 13/105 (12%) Query: 118 RSRSPRRRRRSRSRSRSRSRSRSRSRYSRSKSRSR----------TRSRSRSTSKSRSAR 167 R R R+RRS S S +RSRS S S S S SRS S+S SRS+ Sbjct: 57 RGRDKTRKRRSASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSS 116 Query: 168 RSKSKSS-SVSRSRSRSRSRSRSRSPPPVSKRESKSRSRSKSPPK 211 S S S S SR R +R RSRS+S PP KR+ K R R PK Sbjct: 117 SSSSSGSPSPSRRRHDNRRRSRSKSKPP--KRDEKERKRRSPSPK 159 Score = 49.7 bits (117), Expect = 2e-06 Identities = 36/105 (34%), Positives = 52/105 (49%), Gaps = 10/105 (9%) Query: 118 RSRSPRRRR-RSRSRSRSRSRSRSRSRYSRSKSRSRTRSRSRSTSKSRSARRSKSKSSSV 176 R+ SP +R+ RS +S+ RS+ + ++ S K R R ++R R RS S SS Sbjct: 24 RAPSPTKRKDRSDEKSKDRSKDKGATKESSEKDRGRDKTRKR---------RSASSGSSS 74 Query: 177 SRSRSRSRSRSRSRSPPPVSKRESKSRSRSKSPPKSPEEEGAVSS 221 +RSRS S S S S + S S S + S+S S + SS Sbjct: 75 TRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSS 119 Score = 39.3 bits (90), Expect = 0.003 Identities = 32/80 (40%), Positives = 35/80 (43%), Gaps = 8/80 (10%) Query: 116 GRRSRSPRRRRRSRSRSRSRSRSRSRSRYSRSKSRSRTRSRSRSTSKSRSARRSKSKSSS 175 G S S SRS S S SRS S S S S S SR R +R RRS+SKS Sbjct: 92 GSSSGSSSSSASSRSGSSSTSRSSSSSSSSGSPSPSRRRHDNR--------RRSRSKSKP 143 Query: 176 VSRSRSRSRSRSRSRSPPPV 195 R + RS S P V Sbjct: 144 PKRDEKERKRRSPSPKPTKV 163 Score = 37.0 bits (84), Expect = 0.013 Identities = 27/66 (40%), Positives = 32/66 (48%) Query: 114 GYGRRSRSPRRRRRSRSRSRSRSRSRSRSRYSRSKSRSRTRSRSRSTSKSRSARRSKSKS 173 G S S RS S S SRS S S S S S SR R +R RS SKS+ +R + + Sbjct: 92 GSSSGSSSSSASSRSGSSSTSRSSSSSSSSGSPSPSRRRHDNRRRSRSKSKPPKRDEKER 151 Query: 174 SSVSRS 179 S S Sbjct: 152 KRRSPS 157 Score = 35.8 bits (81), Expect = 0.030 Identities = 27/66 (40%), Positives = 30/66 (45%), Gaps = 2/66 (3%) Query: 112 GGGYGRRSRSPRRRRRSRSRSRSRSRSRSRSRYSRSKSRSRTRSRSRSTSK--SRSARRS 169 G G S S R S S SRS S S S S S+ R R RSRS SK R + Sbjct: 92 GSSSGSSSSSASSRSGSSSTSRSSSSSSSSGSPSPSRRRHDNRRRSRSKSKPPKRDEKER 151 Query: 170 KSKSSS 175 K +S S Sbjct: 152 KRRSPS 157 Score = 28.5 bits (62), Expect = 4.7 Identities = 23/67 (34%), Positives = 31/67 (46%), Gaps = 5/67 (7%) Query: 118 RSRSPRRRRRSRSRSRSRSRSRSRSRY-----SRSKSRSRTRSRSRSTSKSRSARRSKSK 172 RS S R S S S S S S SR R+ SRSKS+ R +S S + +K Sbjct: 105 RSGSSSTSRSSSSSSSSGSPSPSRRRHDNRRRSRSKSKPPKRDEKERKRRSPSPKPTKVH 164 Query: 173 SSSVSRS 179 ++R+ Sbjct: 165 IGRLTRN 171 >gi|18379334 RNA-binding protein S1, serine-rich domain [Homo sapiens] Length = 305 Score = 83.6 bits (205), Expect = 1e-16 Identities = 55/145 (37%), Positives = 78/145 (53%), Gaps = 8/145 (5%) Query: 14 TSLKVDNLTYRTSPDTLRRVFEKYGRVGDVYIPRDR-YTKESRGFAFVRFHDKRDAEDAM 72 T + + LT + D + +F YG++ + +P +R + S+G+A+V F + +AE A+ Sbjct: 161 TKVHIGRLTRNVTKDHIMEIFSTYGKIKMIDMPVERMHPHLSKGYAYVEFENPDEAEKAL 220 Query: 73 DAMDGAVLDGRELRVQ--MARYGRPPDSHHS---RRGPPPR--RYGGGGYGRRSRSPRRR 125 MDG +DG+E+ +A + RPP S R PPP R RRSRSPRRR Sbjct: 221 KHMDGGQIDGQEITATAVLAPWPRPPPRRFSPPRRMLPPPPMWRRSPPRMRRRSRSPRRR 280 Query: 126 RRSRSRSRSRSRSRSRSRYSRSKSR 150 R RSRS R R RSR S + SR Sbjct: 281 SPVRRRSRSPGRRRHRSRSSSNSSR 305 Score = 63.9 bits (154), Expect = 1e-10 Identities = 52/129 (40%), Positives = 66/129 (51%), Gaps = 13/129 (10%) Query: 101 SRRGPPP-RRYGGGGYGRRSRSPRRRRRSRSRSRSRSRSRSRSRYSRSKSRSRTRSRSRS 159 S R P P +R + RS + S + R R ++R R S S S TRSRS S Sbjct: 22 STRAPSPTKRKDRSDEKSKDRSKDKGATKESSEKDRGRDKTRKRRSASSGSSSTRSRSSS 81 Query: 160 TSKSRSARRS-----KSKSSSVSRSRSRSRSRSRSRS-----PPPVSKR-ESKSRSRSKS 208 TS S S+ + S SS+ SRS S S SRS S S P P +R +++ RSRSKS Sbjct: 82 TSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSSSSGSPSPSRRRHDNRRRSRSKS 141 Query: 209 -PPKSPEEE 216 PPK E+E Sbjct: 142 KPPKRDEKE 150 Score = 61.2 bits (147), Expect = 7e-10 Identities = 46/105 (43%), Positives = 53/105 (50%), Gaps = 13/105 (12%) Query: 118 RSRSPRRRRRSRSRSRSRSRSRSRSRYSRSKSRSR----------TRSRSRSTSKSRSAR 167 R R R+RRS S S +RSRS S S S S SRS S+S SRS+ Sbjct: 57 RGRDKTRKRRSASSGSSSTRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSS 116 Query: 168 RSKSKSS-SVSRSRSRSRSRSRSRSPPPVSKRESKSRSRSKSPPK 211 S S S S SR R +R RSRS+S PP KR+ K R R PK Sbjct: 117 SSSSSGSPSPSRRRHDNRRRSRSKSKPP--KRDEKERKRRSPSPK 159 Score = 49.7 bits (117), Expect = 2e-06 Identities = 36/105 (34%), Positives = 52/105 (49%), Gaps = 10/105 (9%) Query: 118 RSRSPRRRR-RSRSRSRSRSRSRSRSRYSRSKSRSRTRSRSRSTSKSRSARRSKSKSSSV 176 R+ SP +R+ RS +S+ RS+ + ++ S K R R ++R R RS S SS Sbjct: 24 RAPSPTKRKDRSDEKSKDRSKDKGATKESSEKDRGRDKTRKR---------RSASSGSSS 74 Query: 177 SRSRSRSRSRSRSRSPPPVSKRESKSRSRSKSPPKSPEEEGAVSS 221 +RSRS S S S S + S S S + S+S S + SS Sbjct: 75 TRSRSSSTSSSGSSTSTGSSSGSSSSSASSRSGSSSTSRSSSSSS 119 Score = 39.3 bits (90), Expect = 0.003 Identities = 32/80 (40%), Positives = 35/80 (43%), Gaps = 8/80 (10%) Query: 116 GRRSRSPRRRRRSRSRSRSRSRSRSRSRYSRSKSRSRTRSRSRSTSKSRSARRSKSKSSS 175 G S S SRS S S SRS S S S S S SR R +R RRS+SKS Sbjct: 92 GSSSGSSSSSASSRSGSSSTSRSSSSSSSSGSPSPSRRRHDNR--------RRSRSKSKP 143 Query: 176 VSRSRSRSRSRSRSRSPPPV 195 R + RS S P V Sbjct: 144 PKRDEKERKRRSPSPKPTKV 163 Score = 37.0 bits (84), Expect = 0.013 Identities = 27/66 (40%), Positives = 32/66 (48%) Query: 114 GYGRRSRSPRRRRRSRSRSRSRSRSRSRSRYSRSKSRSRTRSRSRSTSKSRSARRSKSKS 173 G S S RS S S SRS S S S S S SR R +R RS SKS+ +R + + Sbjct: 92 GSSSGSSSSSASSRSGSSSTSRSSSSSSSSGSPSPSRRRHDNRRRSRSKSKPPKRDEKER 151 Query: 174 SSVSRS 179 S S Sbjct: 152 KRRSPS 157 Score = 35.8 bits (81), Expect = 0.030 Identities = 27/66 (40%), Positives = 30/66 (45%), Gaps = 2/66 (3%) Query: 112 GGGYGRRSRSPRRRRRSRSRSRSRSRSRSRSRYSRSKSRSRTRSRSRSTSK--SRSARRS 169 G G S S R S S SRS S S S S S+ R R RSRS SK R + Sbjct: 92 GSSSGSSSSSASSRSGSSSTSRSSSSSSSSGSPSPSRRRHDNRRRSRSKSKPPKRDEKER 151 Query: 170 KSKSSS 175 K +S S Sbjct: 152 KRRSPS 157 Score = 28.5 bits (62), Expect = 4.7 Identities = 23/67 (34%), Positives = 31/67 (46%), Gaps = 5/67 (7%) Query: 118 RSRSPRRRRRSRSRSRSRSRSRSRSRY-----SRSKSRSRTRSRSRSTSKSRSARRSKSK 172 RS S R S S S S S S SR R+ SRSKS+ R +S S + +K Sbjct: 105 RSGSSSTSRSSSSSSSSGSPSPSRRRHDNRRRSRSKSKPPKRDEKERKRRSPSPKPTKVH 164 Query: 173 SSSVSRS 179 ++R+ Sbjct: 165 IGRLTRN 171 >gi|116089325 splicing factor, arginine/serine-rich 12 isoform a [Homo sapiens] Length = 624 Score = 83.2 bits (204), Expect = 2e-16 Identities = 68/210 (32%), Positives = 103/210 (49%), Gaps = 21/210 (10%) Query: 25 TSPDTLRRVFEKYGRVGDVYIPRDRYTKESRGFAFVRFHDKRDAEDAMDAMDGAVLDGRE 84 T+ D L F++ G V V + D T+ +R FAFV F D+ A+ A +G + R Sbjct: 194 TTADQLLEFFKQVGEVKFVRMAGDE-TQPTR-FAFVEFADQNSVPRAL-AFNGVMFGDRP 250 Query: 85 LRVQMARYG--RPPD----------SHHSRRGPPPRRYGGGGY----GRRSRSPRRRRRS 128 L++ + +PP+ +R + + G+ + R RS Sbjct: 251 LKINHSNNAIVKPPEMTPQAAAKELEEVMKRVREAQSFISAAIEPESGKSNERKGGRSRS 310 Query: 129 RSRSRSRSRSRSRSRYSRSKSRSRTRSRSRSTSKSRSARRSKS--KSSSVSRSRSRSRSR 186 +RS+SRS S+S SR RS+S+ R+RS +RS S+ + RRSKS K S SR R +SRSR Sbjct: 311 HTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSR 370 Query: 187 SRSRSPPPVSKRESKSRSRSKSPPKSPEEE 216 S SR ++ + K + R K + E E Sbjct: 371 SHSRDKRKDTREKIKEKERVKEKDREKERE 400 Score = 61.2 bits (147), Expect = 7e-10 Identities = 40/132 (30%), Positives = 59/132 (44%), Gaps = 9/132 (6%) Query: 94 RPPDSHHSRRGPPPRRYGGGGYGR-RSRSPRRRR-------RSRSRSRSRSRSRSRSRYS 145 R HSRR ++ + R RSR RRR RS+SR R +SRSRS SR Sbjct: 317 RSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDK 376 Query: 146 RSKSRSRTRSRSRSTSKSRSARRSKSKSSSVSRSRSRSRSRSRSRSPP-PVSKRESKSRS 204 R +R + + + R K R R + K + R +++ R + R K + + R Sbjct: 377 RKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDRERE 436 Query: 205 RSKSPPKSPEEE 216 R K K ++E Sbjct: 437 REKEHEKDRDKE 448 Score = 57.0 bits (136), Expect = 1e-08 Identities = 36/91 (39%), Positives = 54/91 (59%), Gaps = 2/91 (2%) Query: 118 RSRSPRRRRRSRSRSRSRSRSRSRSRYSRSKSRSRTRSRSRSTSKS-RSARRSKSKSSSV 176 RS+ +R+ +SR+ RS + SR SRS SR R R RSRS+S+S R+++ K KSS Sbjct: 463 RSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRS 522 Query: 177 SRSRSRS-RSRSRSRSPPPVSKRESKSRSRS 206 RSR+ + + R + +S+R + RS S Sbjct: 523 PSPRSRNKKDKKREKERDHISERRERERSTS 553 Score = 50.8 bits (120), Expect = 9e-07 Identities = 39/116 (33%), Positives = 53/116 (45%), Gaps = 8/116 (6%) Query: 106 PPRRYGGGGYGRRSRSPRRRRRSRSRSRSRSRSRSRSRYSRSKSRSRTRSRS-RSTSKSR 164 PPR Y R S RRRRRSRS SRS R S++ R +RS S RS +K Sbjct: 480 PPRSYNASRRSRSSSRERRRRRSRSSSRS-------PRTSKTIKRKSSRSPSPRSRNKKD 532 Query: 165 SARRSKSKSSSVSRSRSRSRSRSRSRSPPPVSKRESKSRSRSKSPPKSPEEEGAVS 220 R + S R R RS S +S + ++ K+ + K + E + +VS Sbjct: 533 KKREKERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVS 588 Score = 48.9 bits (115), Expect = 3e-06 Identities = 33/126 (26%), Positives = 52/126 (41%), Gaps = 4/126 (3%) Query: 94 RPPDSHHSRRGPPPRRYGGGGYGRRSRSPRRRR-RSRSRSRSRSRSRSR--SRYSRSKSR 150 R + SR RR + +RS+S RR+ RSRS SR + + R K + Sbjct: 334 RSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEK 393 Query: 151 SRTRSRSRSTSKSRSARRSKSKSSSVSRSRSRSRSRSRSRSPPPVSKRESKSRSRSKSPP 210 R + R R + + R K+K R + R + + + R K K R + K Sbjct: 394 DREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDRERER-EKEHEKDRDKEKEKE 452 Query: 211 KSPEEE 216 + E+E Sbjct: 453 QDKEKE 458 Score = 48.1 bits (113), Expect = 6e-06 Identities = 36/112 (32%), Positives = 56/112 (50%), Gaps = 15/112 (13%) Query: 123 RRRRRSRSRSRSRSRSRSRSRYSRSKSRSRTRSRS-----RSTSKSRSARRSKS---KSS 174 R R R + + R + + + + + K R + RS+ + KSR+ RS + +S Sbjct: 433 REREREKEHEKDRDKEKEKEQ-DKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSR 491 Query: 175 SVSRSRSRSRSRSRSRSP---PPVSKRESKS---RSRSKSPPKSPEEEGAVS 220 S SR R R RSRS SRSP + ++ S+S RSR+K K +E +S Sbjct: 492 SSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHIS 543 Score = 47.0 bits (110), Expect = 1e-05 Identities = 40/117 (34%), Positives = 52/117 (44%), Gaps = 18/117 (15%) Query: 117 RRSRSPRRRRRSRSRSRSRSRSRSRSRYSRSKSR----SRTRSRSRSTSKSRSARRSKSK 172 ++SR+P R + RSRS SR R R R SRS SR S+T R S S S +R K K Sbjct: 475 KKSRTPPRSYNASRRSRSSSRERRRRR-SRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDK 533 Query: 173 S-----SSVSRSRSRSRSRSRSRSPPPVSKRES--------KSRSRSKSPPKSPEEE 216 +S R R RS S +S +E K + +K P S +E Sbjct: 534 KREKERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSKE 590 Score = 44.3 bits (103), Expect = 8e-05 Identities = 20/90 (22%), Positives = 43/90 (47%), Gaps = 5/90 (5%) Query: 123 RRRRRSRSRSRSRSRSRSRSRYSRSKSRSRTRSRSRSTSKSRSARRSKSKSSSVSRSRSR 182 R R + R + + R +++ R + R K R + + + R + + + + K + + + Sbjct: 399 REREKEREKEKERGKNKDRDK-EREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEK 457 Query: 183 SRSRSRSRSPPPVSKRESKSRSRSKSPPKS 212 R + RS+ K++ KSR +PP+S Sbjct: 458 EREKDRSKEIDEKRKKDKKSR----TPPRS 483 >gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [Homo sapiens] Length = 508 Score = 83.2 bits (204), Expect = 2e-16 Identities = 68/210 (32%), Positives = 103/210 (49%), Gaps = 21/210 (10%) Query: 25 TSPDTLRRVFEKYGRVGDVYIPRDRYTKESRGFAFVRFHDKRDAEDAMDAMDGAVLDGRE 84 T+ D L F++ G V V + D T+ +R FAFV F D+ A+ A +G + R Sbjct: 78 TTADQLLEFFKQVGEVKFVRMAGDE-TQPTR-FAFVEFADQNSVPRAL-AFNGVMFGDRP 134 Query: 85 LRVQMARYG--RPPD----------SHHSRRGPPPRRYGGGGY----GRRSRSPRRRRRS 128 L++ + +PP+ +R + + G+ + R RS Sbjct: 135 LKINHSNNAIVKPPEMTPQAAAKELEEVMKRVREAQSFISAAIEPESGKSNERKGGRSRS 194 Query: 129 RSRSRSRSRSRSRSRYSRSKSRSRTRSRSRSTSKSRSARRSKS--KSSSVSRSRSRSRSR 186 +RS+SRS S+S SR RS+S+ R+RS +RS S+ + RRSKS K S SR R +SRSR Sbjct: 195 HTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSR 254 Query: 187 SRSRSPPPVSKRESKSRSRSKSPPKSPEEE 216 S SR ++ + K + R K + E E Sbjct: 255 SHSRDKRKDTREKIKEKERVKEKDREKERE 284 Score = 61.2 bits (147), Expect = 7e-10 Identities = 40/132 (30%), Positives = 59/132 (44%), Gaps = 9/132 (6%) Query: 94 RPPDSHHSRRGPPPRRYGGGGYGR-RSRSPRRRR-------RSRSRSRSRSRSRSRSRYS 145 R HSRR ++ + R RSR RRR RS+SR R +SRSRS SR Sbjct: 201 RSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDK 260 Query: 146 RSKSRSRTRSRSRSTSKSRSARRSKSKSSSVSRSRSRSRSRSRSRSPP-PVSKRESKSRS 204 R +R + + + R K R R + K + R +++ R + R K + + R Sbjct: 261 RKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDRERE 320 Query: 205 RSKSPPKSPEEE 216 R K K ++E Sbjct: 321 REKEHEKDRDKE 332 Score = 57.0 bits (136), Expect = 1e-08 Identities = 36/91 (39%), Positives = 54/91 (59%), Gaps = 2/91 (2%) Query: 118 RSRSPRRRRRSRSRSRSRSRSRSRSRYSRSKSRSRTRSRSRSTSKS-RSARRSKSKSSSV 176 RS+ +R+ +SR+ RS + SR SRS SR R R RSRS+S+S R+++ K KSS Sbjct: 347 RSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRS 406 Query: 177 SRSRSRS-RSRSRSRSPPPVSKRESKSRSRS 206 RSR+ + + R + +S+R + RS S Sbjct: 407 PSPRSRNKKDKKREKERDHISERRERERSTS 437 Score = 50.8 bits (120), Expect = 9e-07 Identities = 39/116 (33%), Positives = 53/116 (45%), Gaps = 8/116 (6%) Query: 106 PPRRYGGGGYGRRSRSPRRRRRSRSRSRSRSRSRSRSRYSRSKSRSRTRSRS-RSTSKSR 164 PPR Y R S RRRRRSRS SRS R S++ R +RS S RS +K Sbjct: 364 PPRSYNASRRSRSSSRERRRRRSRSSSRS-------PRTSKTIKRKSSRSPSPRSRNKKD 416 Query: 165 SARRSKSKSSSVSRSRSRSRSRSRSRSPPPVSKRESKSRSRSKSPPKSPEEEGAVS 220 R + S R R RS S +S + ++ K+ + K + E + +VS Sbjct: 417 KKREKERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVS 472 Score = 48.9 bits (115), Expect = 3e-06 Identities = 33/126 (26%), Positives = 52/126 (41%), Gaps = 4/126 (3%) Query: 94 RPPDSHHSRRGPPPRRYGGGGYGRRSRSPRRRR-RSRSRSRSRSRSRSR--SRYSRSKSR 150 R + SR RR + +RS+S RR+ RSRS SR + + R K + Sbjct: 218 RSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEK 277 Query: 151 SRTRSRSRSTSKSRSARRSKSKSSSVSRSRSRSRSRSRSRSPPPVSKRESKSRSRSKSPP 210 R + R R + + R K+K R + R + + + R K K R + K Sbjct: 278 DREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDRERER-EKEHEKDRDKEKEKE 336 Query: 211 KSPEEE 216 + E+E Sbjct: 337 QDKEKE 342 Score = 48.1 bits (113), Expect = 6e-06 Identities = 36/112 (32%), Positives = 56/112 (50%), Gaps = 15/112 (13%) Query: 123 RRRRRSRSRSRSRSRSRSRSRYSRSKSRSRTRSRS-----RSTSKSRSARRSKS---KSS 174 R R R + + R + + + + + K R + RS+ + KSR+ RS + +S Sbjct: 317 REREREKEHEKDRDKEKEKEQ-DKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSR 375 Query: 175 SVSRSRSRSRSRSRSRSP---PPVSKRESKS---RSRSKSPPKSPEEEGAVS 220 S SR R R RSRS SRSP + ++ S+S RSR+K K +E +S Sbjct: 376 SSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHIS 427 Score = 47.0 bits (110), Expect = 1e-05 Identities = 40/117 (34%), Positives = 52/117 (44%), Gaps = 18/117 (15%) Query: 117 RRSRSPRRRRRSRSRSRSRSRSRSRSRYSRSKSR----SRTRSRSRSTSKSRSARRSKSK 172 ++SR+P R + RSRS SR R R R SRS SR S+T R S S S +R K K Sbjct: 359 KKSRTPPRSYNASRRSRSSSRERRRRR-SRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDK 417 Query: 173 S-----SSVSRSRSRSRSRSRSRSPPPVSKRES--------KSRSRSKSPPKSPEEE 216 +S R R RS S +S +E K + +K P S +E Sbjct: 418 KREKERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSKE 474 Score = 44.3 bits (103), Expect = 8e-05 Identities = 20/90 (22%), Positives = 43/90 (47%), Gaps = 5/90 (5%) Query: 123 RRRRRSRSRSRSRSRSRSRSRYSRSKSRSRTRSRSRSTSKSRSARRSKSKSSSVSRSRSR 182 R R + R + + R +++ R + R K R + + + R + + + + K + + + Sbjct: 283 REREKEREKEKERGKNKDRDK-EREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEK 341 Query: 183 SRSRSRSRSPPPVSKRESKSRSRSKSPPKS 212 R + RS+ K++ KSR +PP+S Sbjct: 342 EREKDRSKEIDEKRKKDKKSR----TPPRS 367 >gi|56699409 RNA binding motif protein, X-linked [Homo sapiens] Length = 391 Score = 82.8 bits (203), Expect = 2e-16 Identities = 66/189 (34%), Positives = 83/189 (43%), Gaps = 15/189 (7%) Query: 16 LKVDNLTYRTSPDTLRRVFEKYGRVGDVYIPRDRYTKESRGFAFVRFHDKRDAEDAMDAM 75 L + L T+ L VF KYGR+ +V + +DR T +SRGFAFV F DA+DA M Sbjct: 10 LFIGGLNTETNEKALEAVFGKYGRIVEVLLMKDRETNKSRGFAFVTFESPADAKDAARDM 69 Query: 76 DGAVLDGRELRVQMARYGRPPDSHHSRRGPPP----------RRYGGGGYGRRSRSPRRR 125 +G LDG+ ++V+ A P RRGPPP R G GG G P R Sbjct: 70 NGKSLDGKAIKVEQA---TKPSFESGRRGPPPPPRSRGPPRGLRGGRGGSGGTRGPPSRG 126 Query: 126 RRSRSRSRSRSRSRSRSRYSRSKSRSRTRSRSRSTSKSRSARRSKSKSSSVSRSRSR-SR 184 S + + S SR R RS RSA +SSS R+ SR Sbjct: 127 GHMDDGGYSMNFNMSSSRGPLPVKRG-PPPRSGGPPPKRSAPSGPVRSSSGMGGRAPVSR 185 Query: 185 SRSRSRSPP 193 R PP Sbjct: 186 GRDSYGGPP 194 >gi|4759098 splicing factor, arginine/serine-rich 10 [Homo sapiens] Length = 288 Score = 82.4 bits (202), Expect = 3e-16 Identities = 66/178 (37%), Positives = 83/178 (46%), Gaps = 13/178 (7%) Query: 16 LKVDNLTYRTSPDTLRRVFEKYGRVGDVYIPRDRYTKESRGFAFVRFHDKRDAEDAMDAM 75 L V L+ T+ LR VF KYG + DV I D+ ++ SRGFAFV F + DA++A + Sbjct: 120 LGVFGLSLYTTERDLREVFSKYGPIADVSIVYDQQSRRSRGFAFVYFENVDDAKEAKERA 179 Query: 76 DGAVLDGRELRVQMARYGRPPDSHHSRRGPPPRRYGGGGYGRRSRSPRRRRRSRSRSRSR 135 +G LDGR +RV + RP P P Y GR + RRR R R Sbjct: 180 NGMELDGRRIRVDFSITKRP-------HTPTPGIY----MGRPTYGSSRRRDYYDRGYDR 228 Query: 136 SRSRSRSRYSRS-KSRSRTRSRSRSTSKSRSARRSKSKSSSVSRSRSRSRSRSRSRSP 192 R YSRS + R+ R +S S SR RSRSRSRS SP Sbjct: 229 GYD-DRDYYSRSYRGGGGGGGGWRAAQDRDQIYRRRSPSPYYSRGGYRSRSRSRSYSP 285 Score = 67.0 bits (162), Expect = 1e-11 Identities = 49/101 (48%), Positives = 55/101 (54%), Gaps = 13/101 (12%) Query: 92 YGRPPDSHHSRRGPPPRRYGGGGYGR----RSRSPRRRRRSRSRSRSRSRSRSRSR---- 143 YG SR G +G G R RSRS RRSRS+SRSRS SRSRSR Sbjct: 9 YGERESRSASRSGSA---HGSGKSARHTPARSRSKEDSRRSRSKSRSRSESRSRSRRSSR 65 Query: 144 --YSRSKSRSRTRSRSRSTSKSRSARRSKSKSSSVSRSRSR 182 Y+RS+SRSR+ RSRS S SR RR S S S +R R Sbjct: 66 RHYTRSRSRSRSHRRSRSRSYSRDYRRRHSHSHSPMSTRRR 106 Score = 60.5 bits (145), Expect = 1e-09 Identities = 46/113 (40%), Positives = 60/113 (53%), Gaps = 14/113 (12%) Query: 111 GGGGYGRR-----SRSPRRRRRSRSRSRSRSRSRSRSRYSRSKSRSRTRSRSRSTSKSRS 165 G YG R SRS +S + +RSRS+ RS+S+SR+RS SRS S+ RS Sbjct: 5 GEQNYGERESRSASRSGSAHGSGKSARHTPARSRSKEDSRRSRSKSRSRSESRSRSR-RS 63 Query: 166 ARRSKSKSSSVSRSRSRSRSRSRSR--------SPPPVSKRESKSRSRSKSPP 210 +RR ++S S SRS RSRSRS SR S P+S R +R+ P Sbjct: 64 SRRHYTRSRSRSRSHRRSRSRSYSRDYRRRHSHSHSPMSTRRRHVGNRANPDP 116 Score = 53.5 bits (127), Expect = 1e-07 Identities = 38/79 (48%), Positives = 46/79 (58%), Gaps = 7/79 (8%) Query: 134 SRSRSRSRSRYSRSKSRSRTRSRSRSTSKSRSARRSKSKSSSVSRSRSRSRSRSRSRSPP 193 SRS SRS S + KS T +RSRS SR RS+SKS RSRS SRSRSR S Sbjct: 14 SRSASRSGSAHGSGKSARHTPARSRSKEDSR---RSRSKS----RSRSESRSRSRRSSRR 66 Query: 194 PVSKRESKSRSRSKSPPKS 212 ++ S+SRS +S +S Sbjct: 67 HYTRSRSRSRSHRRSRSRS 85 Score = 41.2 bits (95), Expect = 7e-04 Identities = 32/83 (38%), Positives = 37/83 (44%), Gaps = 3/83 (3%) Query: 82 GRELRVQMARYGRPPDSHHSRRGPPPRRYGGGGYGRRSRSPRRRRRSRSRSRSRSRSRSR 141 G+ R AR DS SR R R SR R RSRSRS RSRSRS Sbjct: 27 GKSARHTPARSRSKEDSRRSRSKSRSRSESRSRSRRSSRRHYTRSRSRSRSHRRSRSRS- 85 Query: 142 SRYSRSKSRSRTRSRSRSTSKSR 164 YSR R + S S +++ R Sbjct: 86 --YSRDYRRRHSHSHSPMSTRRR 106 Score = 35.8 bits (81), Expect = 0.030 Identities = 30/66 (45%), Positives = 39/66 (59%), Gaps = 5/66 (7%) Query: 145 SRSKSRSRTRSRSRSTSKSRSARRS-KSKSSSVSRSRSRSRSR-SRSRSPPPVSKRESKS 202 S S ++ SRS S+S SA S KS + +RSRS+ SR SRS+S S+ ES+S Sbjct: 2 SDSGEQNYGERESRSASRSGSAHGSGKSARHTPARSRSKEDSRRSRSKSR---SRSESRS 58 Query: 203 RSRSKS 208 RSR S Sbjct: 59 RSRRSS 64 >gi|242117971 RNA binding motif protein, X-linked-like 1 [Homo sapiens] Length = 390 Score = 82.0 bits (201), Expect = 4e-16 Identities = 67/189 (35%), Positives = 86/189 (45%), Gaps = 15/189 (7%) Query: 16 LKVDNLTYRTSPDTLRRVFEKYGRVGDVYIPRDRYTKESRGFAFVRFHDKRDAEDAMDAM 75 L + L T+ L VF KYGR+ +V + +DR T +SRGFAFV F DA+DA M Sbjct: 10 LFIGGLNTETNEKALETVFGKYGRIVEVLLIKDRETNKSRGFAFVTFESPADAKDAARDM 69 Query: 76 DGAVLDGRELRVQMA--------RYGRPPDSHHSRRGPPPRRYGG--GGYGRRSRSPRRR 125 +G LDG+ ++V+ A R+G PP R PPR +G GG G P R Sbjct: 70 NGKSLDGKAIKVEQATKPSFERGRHGPPPP---PRSRGPPRGFGAGRGGSGGTRGPPSRG 126 Query: 126 RRSRSRSRSRSRSRSRSRYSRSKSRSRTRSRSRSTSKSRSARRSKSKSSSVSRSRS-RSR 184 S + + S SR R RS S RSA +SSS R+ SR Sbjct: 127 GHMDDGGYSMNFNMSSSRGPLPVKRG-PPPRSGGPSPKRSAPSGLVRSSSGMGGRAPLSR 185 Query: 185 SRSRSRSPP 193 R PP Sbjct: 186 GRDSYGGPP 194 >gi|21361809 RNA binding motif protein, X-linked-like 1 [Homo sapiens] Length = 390 Score = 82.0 bits (201), Expect = 4e-16 Identities = 67/189 (35%), Positives = 86/189 (45%), Gaps = 15/189 (7%) Query: 16 LKVDNLTYRTSPDTLRRVFEKYGRVGDVYIPRDRYTKESRGFAFVRFHDKRDAEDAMDAM 75 L + L T+ L VF KYGR+ +V + +DR T +SRGFAFV F DA+DA M Sbjct: 10 LFIGGLNTETNEKALETVFGKYGRIVEVLLIKDRETNKSRGFAFVTFESPADAKDAARDM 69 Query: 76 DGAVLDGRELRVQMA--------RYGRPPDSHHSRRGPPPRRYGG--GGYGRRSRSPRRR 125 +G LDG+ ++V+ A R+G PP R PPR +G GG G P R Sbjct: 70 NGKSLDGKAIKVEQATKPSFERGRHGPPPP---PRSRGPPRGFGAGRGGSGGTRGPPSRG 126 Query: 126 RRSRSRSRSRSRSRSRSRYSRSKSRSRTRSRSRSTSKSRSARRSKSKSSSVSRSRS-RSR 184 S + + S SR R RS S RSA +SSS R+ SR Sbjct: 127 GHMDDGGYSMNFNMSSSRGPLPVKRG-PPPRSGGPSPKRSAPSGLVRSSSGMGGRAPLSR 185 Query: 185 SRSRSRSPP 193 R PP Sbjct: 186 GRDSYGGPP 194 >gi|4759100 splicing factor, arginine/serine-rich 11 [Homo sapiens] Length = 484 Score = 80.9 bits (198), Expect = 8e-16 Identities = 51/92 (55%), Positives = 58/92 (63%), Gaps = 2/92 (2%) Query: 122 PRRRRRSRSRSRSRSRSRSRSRYSRSKSR-SRTRSRSRSTSKSRSARRSKSKSSSVSRSR 180 P ++ R SRSRSRSR R S S+ R SR+RSR RS SKSRS RRSKS S SR Sbjct: 239 PDKKEEKRRHSRSRSRSRRRRTPSSSRHRRSRSRSRRRSHSKSRSRRRSKSPRRRRSHSR 298 Query: 181 SRSRSRSRSRSPPPVSKRESKSRSRSKSPPKS 212 R R RSRS S K+E K + RSK+PPKS Sbjct: 299 ERGR-RSRSTSKTRDKKKEDKEKKRSKTPPKS 329 Score = 72.0 bits (175), Expect = 4e-13 Identities = 60/133 (45%), Positives = 74/133 (55%), Gaps = 22/133 (16%) Query: 91 RYGRPPDSHHSRRGPPPRRYGGGGYGRRSRSPRRRRRSRSRSRSRSRSRSRSRYSRSKSR 150 R+ R RR P R+ RRSRS R RRRS S+SRSR RS+S R RS SR Sbjct: 247 RHSRSRSRSRRRRTPSSSRH------RRSRS-RSRRRSHSKSRSRRRSKS-PRRRRSHSR 298 Query: 151 SRTRSRSRSTSKSR-------SARRSKSKSSSVSRSRSRSRSRSRSRSPPPVSKRESKSR 203 R R RSRSTSK+R +RSK+ S S +R RSRS SR R +R S+S Sbjct: 299 ERGR-RSRSTSKTRDKKKEDKEKKRSKTPPKSYSTAR-RSRSASRER-----RRRRSRSG 351 Query: 204 SRSKSPPKSPEEE 216 +RS P+SP+ + Sbjct: 352 TRSPKKPRSPKRK 364 Score = 70.1 bits (170), Expect = 1e-12 Identities = 53/142 (37%), Positives = 72/142 (50%), Gaps = 15/142 (10%) Query: 86 RVQMARYGRPPDSHHSRRGPPPRR--YGGGGYGRRSRSPRRRRRSRS-----RSRSRSRS 138 R + R P S H R RR + RRS+SPRRRR S S RSRS S++ Sbjct: 252 RSRSRRRRTPSSSRHRRSRSRSRRRSHSKSRSRRRSKSPRRRR-SHSRERGRRSRSTSKT 310 Query: 139 RSRSRYSRSKSRSRTRSRS-----RSTSKSRSARRSKSKSSSVSRSRSRSRSRSRSRSPP 193 R + + + K RS+T +S RS S SR RR +S+S + S + RS R SRSP Sbjct: 311 RDKKKEDKEKKRSKTPPKSYSTARRSRSASRERRRRRSRSGTRSPKKPRSPKRKLSRSPS 370 Query: 194 PVSKRESKSRSRSKSPPKSPEE 215 P +R K + + K +S +E Sbjct: 371 P--RRHKKEKKKDKDKERSRDE 390 Score = 69.7 bits (169), Expect = 2e-12 Identities = 62/141 (43%), Positives = 73/141 (51%), Gaps = 32/141 (22%) Query: 100 HSRRGPPPRRYGGGGYGRRSRSPRRRRRSRSRSRSRSRSRSRSRYSRSKSRSRTRS---- 155 HSR RR RR+ S R RRSRSRSR RS S+SRSR RSKS R RS Sbjct: 248 HSRSRSRSRR-------RRTPSSSRHRRSRSRSRRRSHSKSRSR-RRSKSPRRRRSHSRE 299 Query: 156 ---RSRSTSKSRSAR-------RSKS---------KSSSVSRSRSRSRSRSRSRSPP-PV 195 RSRSTSK+R + RSK+ +S S SR R R RSRS +RSP P Sbjct: 300 RGRRSRSTSKTRDKKKEDKEKKRSKTPPKSYSTARRSRSASRERRRRRSRSGTRSPKKPR 359 Query: 196 SKRESKSRSRSKSPPKSPEEE 216 S + SRS S K +++ Sbjct: 360 SPKRKLSRSPSPRRHKKEKKK 380 Score = 57.0 bits (136), Expect = 1e-08 Identities = 39/122 (31%), Positives = 56/122 (45%), Gaps = 3/122 (2%) Query: 98 SHHSRRGPPPRRYGGGGYGRRSRSPRRRRRSRSRSRSRSRSRSRSRYSRSKSRSRTRSRS 157 S + P RR GRRSRS + R + + + RS++ + + RSR+ SR Sbjct: 283 SRRRSKSPRRRRSHSRERGRRSRSTSKTRDKKKEDKEKKRSKTPPKSYSTARRSRSASRE 342 Query: 158 RSTSKSRSARRSKSKSSSVSRSRSRSRSRSRSRSPPPVSKRESKS---RSRSKSPPKSPE 214 R +SRS RS K S R SRS S R + K + +S R RS S K + Sbjct: 343 RRRRRSRSGTRSPKKPRSPKRKLSRSPSPRRHKKEKKKDKDKERSRDERERSTSKKKKSK 402 Query: 215 EE 216 ++ Sbjct: 403 DK 404 Score = 53.1 bits (126), Expect = 2e-07 Identities = 39/147 (26%), Positives = 58/147 (39%), Gaps = 11/147 (7%) Query: 83 RELRVQMARYGRPPDSHHSRRGPPPRRYGGGGYGRRSRSPRRRRRSRSRSRS-------- 134 R R + D R PP+ Y R + RRRRRSRS +RS Sbjct: 303 RSRSTSKTRDKKKEDKEKKRSKTPPKSYSTARRSRSASRERRRRRSRSGTRSPKKPRSPK 362 Query: 135 --RSRSRSRSRYSRSKSRSRTRSRSRSTSKSRSARRSKSKSSSVSRSRSRSRSRSRSRSP 192 SRS S R+ + K + + + RSR + ++++ KSK R R + + Sbjct: 363 RKLSRSPSPRRHKKEKKKDKDKERSRDERERSTSKKKKSKDKEKDRERKSESDKDVKQVT 422 Query: 193 PPVSKRESKSRS-RSKSPPKSPEEEGA 218 + E S + K K P E G+ Sbjct: 423 RDYDEEEQGYDSEKEKKEEKKPIETGS 449 Score = 40.4 bits (93), Expect = 0.001 Identities = 29/89 (32%), Positives = 40/89 (44%), Gaps = 5/89 (5%) Query: 121 SPRRRRRSRSRSRSRSRSRSRSRYSRSKSRSRTRSRSRSTSKSRSARRSKSKSSSVSRSR 180 SP + + S+ + R R S + + SRS RS+ + + S Sbjct: 207 SPSLKSDTSSKEIEEAMKRVREAQSLISAAIEPDKKEEKRRHSRSRSRSRRRRTPSSSRH 266 Query: 181 SRSRSRSRSRSPPPVSKRESKSRSRSKSP 209 RSRSRSR R S +S+SR RSKSP Sbjct: 267 RRSRSRSRRR-----SHSKSRSRRRSKSP 290 >gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens] Length = 2752 Score = 79.7 bits (195), Expect = 2e-15 Identities = 65/159 (40%), Positives = 80/159 (50%), Gaps = 49/159 (30%) Query: 101 SRRGPPPRRYGGGGYGRRS-------RSPRRRRRSRSRSRSRSRSRSRSR---------- 143 SR RR GG GY RS R+ RRRR RSR+ SR RSRSR Sbjct: 1806 SRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSR 1865 Query: 144 -----------------YSRSKSRSRTRSRSRSTSKSRSA---RRSKSKSSSVSRSRSRS 183 SR +SRSRT SR S+SR++ RRS+S++S VSR RSRS Sbjct: 1866 SRASPATHRRSRSRTPLISRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRS 1925 Query: 184 RS----RSRSRSPPPVSKRESKSR--------SRSKSPP 210 R+ R RSRS P ++R S+SR SRS++PP Sbjct: 1926 RTPPVTRRRSRSRTPTTRRRSRSRTPPVTRRRSRSRTPP 1964 Score = 79.0 bits (193), Expect = 3e-15 Identities = 64/149 (42%), Positives = 83/149 (55%), Gaps = 17/149 (11%) Query: 82 GRELRVQMARYGR-----PPDSHHSR-RGPPPRRYGGGGYGRRSRSPRRRRRSRSRSR-- 133 GR A+ GR P HSR R P RR RSRSP+RR RSRS R Sbjct: 482 GRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPG 541 Query: 134 -SRSRSRSRSRYSRSKSRSRTRSRSRST---SKSRS-ARRSKSKSSSVSRSRSRSRS--- 185 SRSR+ R SRS R R+ SRS +T S+SR+ ARR +S+S + +R RSRSR+ Sbjct: 542 WSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTR 601 Query: 186 -RSRSRSPPPVSKRESKSRSRSKSPPKSP 213 RSRSR+P + S++ +R +S +SP Sbjct: 602 RRSRSRTPARRGRSRSRTPARRRSRTRSP 630 Score = 79.0 bits (193), Expect = 3e-15 Identities = 58/140 (41%), Positives = 79/140 (56%), Gaps = 12/140 (8%) Query: 83 RELRVQMARYGRPPDSHHSRRGPPPRRYGGGGYGRRSRSPRRRRRSRSRSRSRSRSRSRS 142 R R + AR GR + RG R RSR+P RRR SRSR+ +R RSRSR+ Sbjct: 550 RRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRR-SRSRTPTRRRSRSRT 608 Query: 143 RYSRSKSRSRTRSRSRSTSKSRSARRSKSKSSSVSRSRSRSRS-----RSRSRSPPPVSK 197 R +SRSRT +R RS ++S RRS+S+S + RSRSR+ RSRSR+P + Sbjct: 609 PARRGRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGR 668 Query: 198 RESKS------RSRSKSPPK 211 S++ RSRS++P + Sbjct: 669 SRSRTPARRSGRSRSRTPAR 688 Score = 76.6 bits (187), Expect = 2e-14 Identities = 61/140 (43%), Positives = 75/140 (53%), Gaps = 21/140 (15%) Query: 94 RPPDSHHSRRGPPPRRYG------GGGYGR-RSRSPRRRRRSRSRSRSRSRSRSRSRYSR 146 R P SR P RR G GR RSR+P RR RSRSR+ +R RSRSR Sbjct: 628 RSPVRRRSRSRSPARRSGRSRSRTPARRGRSRSRTPARRGRSRSRTPARRSGRSRSRTPA 687 Query: 147 SKSRSRTRSRSRSTSKSRS------------ARRSKSKSSSVSRSRSR-SRSRSRSRSPP 193 + RSR+R+ R S+SRS RR +S SSS +++SR S+ RSRS S P Sbjct: 688 RRGRSRSRTPRRGRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSP 747 Query: 194 PVSK-RESKSRSRSKSPPKS 212 + K R S RSRS S P+S Sbjct: 748 EMKKSRISSRRSRSLSSPRS 767 Score = 75.9 bits (185), Expect = 3e-14 Identities = 57/117 (48%), Positives = 76/117 (64%), Gaps = 24/117 (20%) Query: 117 RRSRS---PRRRRRSRSRSR--SRSRSRSRSRYSRSKSRSR----TRSRSRSTSKSRSAR 167 RRSRS P RRRSRSR+ +R RSRSR+ +R +SRSR TR RSRS + + R Sbjct: 1909 RRSRSRASPVSRRRSRSRTPPVTRRRSRSRTPTTRRRSRSRTPPVTRRRSRSRTPPVTRR 1968 Query: 168 RSKSKSSSVSRSRSRSRS------RSRSRSPPPVSKRESKS--------RSRSKSPP 210 RS+S++S ++R RSRSR+ RSRSR+ PV++R S+S RSRS++PP Sbjct: 1969 RSRSRTSPITRRRSRSRTSPVTRRRSRSRT-SPVTRRRSRSRTSPVTRRRSRSRTPP 2024 Score = 74.7 bits (182), Expect = 6e-14 Identities = 65/151 (43%), Positives = 80/151 (52%), Gaps = 21/151 (13%) Query: 82 GRELRVQMARYGRPPDSHHSRRGPPPRRYGGGGYGR-RSRSPRRRRRSRSRSRSRSRSRS 140 GR AR GR +RRG R GR RSR+P RR RSRSR+ R RSRS Sbjct: 645 GRSRSRTPARRGRSRSRTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRS 704 Query: 141 RSRYSRSKSRSRT---RSRSRSTS----KSR-SARRSKS------KSSSVSRSRSRSRSR 186 RS R +S SRT R RS S+S KSR S RRS+S K S +S RSRS S Sbjct: 705 RSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSRISSRRSRSLSS 764 Query: 187 SRSRSPPPVSKRESKS------RSRSKSPPK 211 RS++ +S R S S + +S++PP+ Sbjct: 765 PRSKAKSRLSLRRSLSGSSPCPKQKSQTPPR 795 Score = 73.2 bits (178), Expect = 2e-13 Identities = 64/149 (42%), Positives = 83/149 (55%), Gaps = 30/149 (20%) Query: 94 RPPDSHHSRRGPPPRRYGGGGYGRRSRSPRRRRRSRSRSRSRSRSRSRS---RYSRSKSR 150 R P SR P RR RSR+P RR RSRSR+ +R RSR+RS R SRS+S Sbjct: 587 RTPARRRSRSRTPTRRRS------RSRTPARRGRSRSRTPARRRSRTRSPVRRRSRSRSP 640 Query: 151 SRT--RSRSRSTS---KSRS---ARRSKSKSSSVSRSRSRSRSRS-----RSRSPPPVSK 197 +R RSRSR+ + +SRS ARR +S+S + +R RSRSR+ RSRS P Sbjct: 641 ARRSGRSRSRTPARRGRSRSRTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSRTP--- 697 Query: 198 RESKSRSRS-----KSPPKSPEEEGAVSS 221 R +SRSRS +S ++P+ G S Sbjct: 698 RRGRSRSRSLVRRGRSHSRTPQRRGRSGS 726 Score = 70.9 bits (172), Expect = 8e-13 Identities = 67/154 (43%), Positives = 82/154 (53%), Gaps = 38/154 (24%) Query: 94 RPPDSHHSRRGPPPRRYGGGGYGR-------RSRSP-RRRRRSRSRSRSRSRSRSRSRYS 145 R P SR P RR G R R+RSP RRR RSRS +R RSRSR+ Sbjct: 597 RTPTRRRSRSRTPARR--GRSRSRTPARRRSRTRSPVRRRSRSRSPARRSGRSRSRTPAR 654 Query: 146 RSKSRSRT-----RSRSRS----TSKSRS---ARRSKSKSSSVSRSRSRSRS-----RSR 188 R +SRSRT RSRSR+ + +SRS ARR +S+S + R RSRSRS RS Sbjct: 655 RGRSRSRTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRRGRSRSRSLVRRGRSH 714 Query: 189 SRSPP------PVSKRESKS-----RSRSKSPPK 211 SR+P S+R++KS RSRS S P+ Sbjct: 715 SRTPQRRGRSGSSSERKNKSRTSQRRSRSNSSPE 748 Score = 70.5 bits (171), Expect = 1e-12 Identities = 65/151 (43%), Positives = 78/151 (51%), Gaps = 44/151 (29%) Query: 103 RGPPPRRYGGGGYGRRSRS---PRRRRRSRSRSRSRSRSRSRSRYS---RSKSRSRT--- 153 R PP R RRSRS P RRRSRSR+ +R RSRSR S R +SRSRT Sbjct: 1961 RTPPVTR-------RRSRSRTSPITRRRSRSRTSPVTRRRSRSRTSPVTRRRSRSRTSPV 2013 Query: 154 ---RSRSRSTSKSRSARRSKSKSSSVSRSRSRSRS------RSRSRSP------------ 192 RSRSR+ R RRS+S++ + R RSRSRS RSRSR+P Sbjct: 2014 TRRRSRSRTPPAIR--RRSRSRTPLLPRKRSRSRSPLAIRRRSRSRTPRTARGKRSLTRS 2071 Query: 193 PPVSKRESKS-----RSRSKSPPKSPEEEGA 218 PP +R S S RSRS +PP + G+ Sbjct: 2072 PPAIRRRSASGSSSDRSRSATPPATRNHSGS 2102 Score = 70.1 bits (170), Expect = 1e-12 Identities = 62/154 (40%), Positives = 82/154 (53%), Gaps = 27/154 (17%) Query: 82 GRELRVQMARYGRPPDSHHSRRGPPPRRYGGGGYGRR----SRSPRRRRRSRSRS----- 132 GR Q R P R +R G RR SRSP R RSRSR+ Sbjct: 523 GRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRG 582 Query: 133 RSRSRSRSRSRYSRSKSRSRTRSRSRSTSKSRSARRSKSKSSSVSRSRSRSRS----RSR 188 RSRSR+ +R R SRS++ +R RSRSR+ ARR +S+S + +R RSR+RS RSR Sbjct: 583 RSRSRTPARRR-SRSRTPTRRRSRSRT-----PARRGRSRSRTPARRRSRTRSPVRRRSR 636 Query: 189 SRSPPPVSKRESKSRSRS-----KSPPKSPEEEG 217 SRSP ++R +SRSR+ +S ++P G Sbjct: 637 SRSP---ARRSGRSRSRTPARRGRSRSRTPARRG 667 Score = 69.7 bits (169), Expect = 2e-12 Identities = 53/118 (44%), Positives = 70/118 (59%), Gaps = 18/118 (15%) Query: 118 RSRSPRRRRRSRSRSRSRSRSRSRSRYSRSKS---RSRTRS-------RSRSTSK---SR 164 RSR+P +R SRSRS RSRS R+ RS+S R R+RS RSR+T + SR Sbjct: 496 RSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRNTQRRGRSR 555 Query: 165 SARRSKSKSSS-VSRSRSRSRS---RSRSRSPPPVSKR-ESKSRSRSKSPPKSPEEEG 217 SARR +S S S +R RSRSR+ R RSRS P +R S++ +R +S ++P G Sbjct: 556 SARRGRSHSRSPATRGRSRSRTPARRGRSRSRTPARRRSRSRTPTRRRSRSRTPARRG 613 Score = 63.2 bits (152), Expect = 2e-10 Identities = 50/122 (40%), Positives = 61/122 (50%), Gaps = 14/122 (11%) Query: 98 SHHSRRGPPPRRYGGGGYGRR-SRSPRRRRRSRSRSR------SRSRSRSRSRYSRSKSR 150 S R PR GR S PR +RSRSRSR +R R RS S S S+ R Sbjct: 1742 SRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRR 1801 Query: 151 SRTRSRSRSTSKSR--SARRSKSKSSSVSRSRSRSRSRSRSRSPPPVSKRESKSRSRSKS 208 R+RSRSR T + R S S+S + S S R R RSR+PP S+ RSRS++ Sbjct: 1802 QRSRSRSRVTRRRRGGSGYHSRSPARQESSRTSSRRRRGRSRTPP-----TSRKRSRSRT 1856 Query: 209 PP 210 P Sbjct: 1857 SP 1858 Score = 62.0 bits (149), Expect = 4e-10 Identities = 53/140 (37%), Positives = 69/140 (49%), Gaps = 28/140 (20%) Query: 101 SRRGPPPRRYGGGGYGRRSRSPRRRRRS-RSRSRSRSRSRSRSRYSRSKSRSRTRSR--- 156 SRRG P G RSRS R + R+ R R RS S + R RS+SRSR R Sbjct: 1757 SRRGRSPSPKPRGLQRSRSRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRG 1816 Query: 157 -----SRSTSKSRSA------RRSKSKSSSVSRSRSRSRS------RSRSRSPPPVSKRE 199 SRS ++ S+ RR +S++ SR RSRSR+ RSRSR+ P +R Sbjct: 1817 GSGYHSRSPARQESSRTSSRRRRGRSRTPPTSRKRSRSRTSPAPWKRSRSRASPATHRRS 1876 Query: 200 -------SKSRSRSKSPPKS 212 S+ RSRS++ P S Sbjct: 1877 RSRTPLISRRRSRSRTSPVS 1896 Score = 61.6 bits (148), Expect = 5e-10 Identities = 55/148 (37%), Positives = 71/148 (47%), Gaps = 35/148 (23%) Query: 95 PPDSHHSRRGP------------PPRRYGGGGYGRRSRSPRRRRRSRSRSRS-RSRSRSR 141 PP S +RRG PPRR +R R RRSRS S S +RSR+ Sbjct: 1662 PPKSRTARRGSRSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTP 1721 Query: 142 SRYSRS----------KSRSRTRSRSRSTSKSRS-ARRSKS---KSSSVSRSRSRS---- 183 R+ RS KSRS R RS S+ ++++ +RR +S K + RSRSRS Sbjct: 1722 PRHRRSPSVSSPEPAEKSRSSRRRRSASSPRTKTTSRRGRSPSPKPRGLQRSRSRSRREK 1781 Query: 184 ----RSRSRSRSPPPVSKRESKSRSRSK 207 R R RS S S+R +SRSRS+ Sbjct: 1782 TRTTRRRDRSGSSQSTSRRRQRSRSRSR 1809 Score = 58.5 bits (140), Expect = 4e-09 Identities = 53/129 (41%), Positives = 65/129 (50%), Gaps = 30/129 (23%) Query: 116 GRRSRS--PRR-RRRSRSRSRSRSRSRSRSRYSRS-------KSRSRTRSRSRSTS---K 162 GRRS S PRR R++S + + RS S S+ R RS KS+ + R RSRST+ K Sbjct: 197 GRRSESSSPRRERKKSSKKKKHRSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTPAPK 256 Query: 163 SRSARRSKS--KSSSVSRSRSRSRSRS--------RSRSPPPVSKRE-------SKSRSR 205 SR A RS S +SS SRSRSRS + RSP P S R S+ + Sbjct: 257 SRRAHRSTSADSASSSDTSRSRSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTT 316 Query: 206 SKSPPKSPE 214 S P SPE Sbjct: 317 STQRPSSPE 325 Score = 57.8 bits (138), Expect = 7e-09 Identities = 34/101 (33%), Positives = 51/101 (50%), Gaps = 4/101 (3%) Query: 106 PPRRYG--GGGYGRRSRSPRRRRRSRSRSRSRSRSRSRSRYSRSKSRSRTRSRSRSTSKS 163 PP+ Y RS +P+++++ + + R R S R R KS + + RS S SK Sbjct: 167 PPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRRSESSSPRRERKKSSKKKKHRSESESKK 226 Query: 164 RSARRSKSKSSSVSRSRSRSRSRSRSRSPPPVSKRESKSRS 204 R R KS +S+ + R RSRS +P P S+R +S S Sbjct: 227 RKHRSPTPKSKR--KSKDKKRKRSRSTTPAPKSRRAHRSTS 265 Score = 56.6 bits (135), Expect = 2e-08 Identities = 39/105 (37%), Positives = 53/105 (50%), Gaps = 11/105 (10%) Query: 119 SRSPRRRRRSRSR---------SRSRSRSRSRSRYSRSKSRSRTRSRSRSTSKSRSARRS 169 S P+RR R + S R S SRS + K + + + R R S+S S RR Sbjct: 150 SFDPQRRAREAKQPAPEPPKPYSLVRESSSSRSPTPKQKKKKKKKDRGRR-SESSSPRRE 208 Query: 170 KSKSSSVSRSRSRSRSRSRS-RSPPPVSKRESKSRSRSKSPPKSP 213 + KSS + RS S S+ R RSP P SKR+SK + R +S +P Sbjct: 209 RKKSSKKKKHRSESESKKRKHRSPTPKSKRKSKDKKRKRSRSTTP 253 Score = 55.5 bits (132), Expect = 4e-08 Identities = 49/134 (36%), Positives = 63/134 (47%), Gaps = 21/134 (15%) Query: 96 PDSHHSRRGPPPRRYGGGGYGRRSRSPRRRRRSRSRSRSRSRSRSRSRYSRSKSRSRT-- 153 P SH P + G +R +S S + SR RSRS + R +SRSRT Sbjct: 447 PGSHREISSSPTSKNRSHGRAKRDKS-----HSHTPSRRMGRSRSPATAKRGRSRSRTPT 501 Query: 154 -----RSRSRSTSKSRSARRSKSKSSSVSRSRSRSRSR---SRSRSPPPVSKRESKSRS- 204 RSRS +SRSA+R S R RSRS R SRSR+ ++R +SRS Sbjct: 502 KRGHSRSRSPQWRRSRSAQRWGRSRSPQRRGRSRSPQRPGWSRSRN----TQRRGRSRSA 557 Query: 205 -RSKSPPKSPEEEG 217 R +S +SP G Sbjct: 558 RRGRSHSRSPATRG 571 Score = 55.1 bits (131), Expect = 5e-08 Identities = 57/166 (34%), Positives = 77/166 (46%), Gaps = 34/166 (20%) Query: 82 GRELRVQMARYGRPPDSHHSRRGPPPRRYGGGGYGRR---SRSPRRR------------- 125 GR + R GR HSR P RR G R SR+ +RR Sbjct: 700 GRSRSRSLVRRGRS----HSRT--PQRRGRSGSSSERKNKSRTSQRRSRSNSSPEMKKSR 753 Query: 126 ---RRSRSRSRSRSRSRSRSRYSRSKSRSRTRSRSRSTSKSRSARRSKSKSSSVSRSRSR 182 RRSRS S RS+++SR RS S S + +S + R +R S+ + SR+ R Sbjct: 754 ISSRRSRSLSSPRSKAKSRLSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPR 813 Query: 183 SRSRSRSRSPPPVSKRESKSR-SRSKSPPK------SPEEEGAVSS 221 RSRS S SPPP K ++ SR S S S P +P +G+++S Sbjct: 814 -RSRS-SSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQGSITS 857 Score = 54.3 bits (129), Expect = 8e-08 Identities = 49/144 (34%), Positives = 62/144 (43%), Gaps = 20/144 (13%) Query: 86 RVQMARYGRPPDSHHSRRGPPPRRYGGGGYGRRSRSPRRRRRSRSRSRSRSRSRSRSRYS 145 R Q P + R P R G R SP + S +SR+ R S Sbjct: 1613 RAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARRGS 1672 Query: 146 RS----KSRSRTRSRSRS-------TSKSRSARRSKSKSSSVSRSRSRSRSRSRSR---- 190 RS K++SRT R RS T K+R +RRS+S SSS +RSR+ R R Sbjct: 1673 RSSPEPKTKSRTPPRRRSSRSSPELTRKARLSRRSRSASSS---PETRSRTPPRHRRSPS 1729 Query: 191 --SPPPVSKRESKSRSRSKSPPKS 212 SP P K S R RS S P++ Sbjct: 1730 VSSPEPAEKSRSSRRRRSASSPRT 1753 Score = 48.5 bits (114), Expect = 4e-06 Identities = 34/108 (31%), Positives = 52/108 (48%), Gaps = 9/108 (8%) Query: 118 RSRSPRRRRRSRSRSRSRSRSRSRSRYSRSKSRSRTRSRSRSTSKSRSARRSKSKSSSVS 177 RS +P+ +R+S+ + R RSRS + + SR RS + + S+ SRS RS + + + Sbjct: 230 RSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHTT 289 Query: 178 RSRSRSRSRS---RSRSPPPVSKRESKSRSRSKSP------PKSPEEE 216 RS S + R P S+ + S R SP P SP E+ Sbjct: 290 ALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYED 337 Score = 48.1 bits (113), Expect = 6e-06 Identities = 44/132 (33%), Positives = 59/132 (44%), Gaps = 15/132 (11%) Query: 105 PPPRRYGGGGYGRRSRSPRRRRRSRSRSRSRSRSRSRSRYSRSKSRSRTRSRSRSTSKSR 164 P P+ G +R+RRS S S S S S S S S S S S + S S S+S S Sbjct: 2584 PAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2643 Query: 165 SARRSKSKSSSVSRSRSRSRS---------RSRSRSPPPVSKRESKSRS------RSKSP 209 S+ S S + ++ + S RSRS P S R+S+S S R SP Sbjct: 2644 SSSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSP 2703 Query: 210 PKSPEEEGAVSS 221 SP ++ + SS Sbjct: 2704 QPSPRDQQSSSS 2715 Score = 47.4 bits (111), Expect = 1e-05 Identities = 44/133 (33%), Positives = 61/133 (45%), Gaps = 11/133 (8%) Query: 85 LRVQMARYGRPPDSHHSRRGPPPRRYGGGGYGRRSRSPRRRRRSRSRSRSRSRSRSRSRY 144 L + +R G P+ R P R G ++P R R RSRS S S+ R Sbjct: 1591 LSPRRSRSGSSPEVKDKPRAAP-RAQSGSDSSPEPKAPAPRALPR---RSRSGSSSKGRG 1646 Query: 145 SRSKSRSRTRSRSRSTSKSRSARRSKSKSSSVSRSRSRSRSRSR---SRSPPPVSKRESK 201 + S T S KSR+ARR S S +++SR+ R SRS P ++++ Sbjct: 1647 PSPEGSSSTESSPEHPPKSRTARRG---SRSSPEPKTKSRTPPRRRSSRSSPELTRKARL 1703 Query: 202 SRSRSKSPPKSPE 214 SR RS+S SPE Sbjct: 1704 SR-RSRSASSSPE 1715 Score = 46.6 bits (109), Expect = 2e-05 Identities = 36/100 (36%), Positives = 52/100 (52%), Gaps = 7/100 (7%) Query: 118 RSRSP-RRRRRSRSRSRSRSRSRSRSRYSRSKS----RSRTRSRSRSTSKSRSARRSKSK 172 ++R+P R+R RS S S+SR R SRS S + + R+ R+ S S S+ K+ Sbjct: 1568 KTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAP 1627 Query: 173 SSSVSRSRSRSRSRSRSRSPPPVSKRESKSRSRSKSPPKS 212 + RSRS S S+ R P P + S + S + PPKS Sbjct: 1628 APRALPRRSRSGSSSKGRGPSP--EGSSSTESSPEHPPKS 1665 Score = 45.8 bits (107), Expect = 3e-05 Identities = 36/132 (27%), Positives = 56/132 (42%), Gaps = 17/132 (12%) Query: 106 PPRRYGGGGY--GRRSRSPRRRRRSRSRSRSRSRSRSRSRYSRSKSRSRTRSRSRSTSKS 163 PPRR G +SR+P RR RS S + +S++ SR S S S + +S + + Sbjct: 793 PPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSRQSHSSSSPHPKVKSGTPPRQ 852 Query: 164 RSARRSKSKSSSVS---------------RSRSRSRSRSRSRSPPPVSKRESKSRSRSKS 208 S ++ SV+ +SR+ SR SPP V +S S+S Sbjct: 853 GSITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGSSPPRVKSSTPPRQSPSRS 912 Query: 209 PPKSPEEEGAVS 220 P+ + +S Sbjct: 913 SSPQPKVKAIIS 924 Score = 45.4 bits (106), Expect = 4e-05 Identities = 40/127 (31%), Positives = 56/127 (44%), Gaps = 11/127 (8%) Query: 96 PDSHHSRRGPPP------RRYGGGGYGRRSRSPRRRRRSRSRSRSRSRSRSRSRYSRSKS 149 P S S PP R+ +P S S++RS R R KS Sbjct: 413 PQSSSSESSPPSPQPTKVSRHASSSPESPKPAPAPGSHREISSSPTSKNRSHGRAKRDKS 472 Query: 150 RSRTRSRSRSTSKS-RSARRSKSKSSSVSR---SRSRSRSRSRSRSPPPVSK-RESKSRS 204 S T SR S+S +A+R +S+S + ++ SRSRS RSRS + R + R Sbjct: 473 HSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSRSPQRRG 532 Query: 205 RSKSPPK 211 RS+SP + Sbjct: 533 RSRSPQR 539 Score = 45.4 bits (106), Expect = 4e-05 Identities = 40/143 (27%), Positives = 61/143 (42%), Gaps = 18/143 (12%) Query: 85 LRVQMARYGRPPDSHHSRRGPPPRRYGGGGYGR-RSRSPRRRRRSRSRSRSRSRSRSRSR 143 L ++ + G P + PP R G + +SR+P RR RS S + +S++ SR Sbjct: 773 LSLRRSLSGSSPCPKQKSQTPPRRSRSGSSQPKAKSRTPPRRSRSSSSPPPKQKSKTPSR 832 Query: 144 YSRSKSRSRTRSRSRSTSKSRSARRSKSKSSSVS---------------RSRSRSRSRSR 188 S S S + +S + + S ++ SV+ +SR+ SR Sbjct: 833 QSHSSSSPHPKVKSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCS 892 Query: 189 SRSPPPV--SKRESKSRSRSKSP 209 SPP V S +S SRS SP Sbjct: 893 GSSPPRVKSSTPPRQSPSRSSSP 915 Score = 45.4 bits (106), Expect = 4e-05 Identities = 43/118 (36%), Positives = 58/118 (49%), Gaps = 7/118 (5%) Query: 102 RRGPPPRR--YGGGGYGRRSRSPRRRRRSRSRSRSRSRSRSRSRYSRSKSRSRTRSRSRS 159 + G PPR+ +S +P+RR S +SR+ SR+S S S S R +S S Sbjct: 845 KSGTPPRQGSITSPQANEQSVTPQRRSCFESSPDPELKSRTPSRHSCSGS-SPPRVKS-S 902 Query: 160 TSKSRSARRSKS---KSSSVSRSRSRSRSRSRSRSPPPVSKRESKSRSRSKSPPKSPE 214 T +S RS S K ++ R RS S S S SP V+ R + RSRS SP + E Sbjct: 903 TPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSSPSPSRVTSRTTPRRSRSVSPCSNVE 960 Score = 45.4 bits (106), Expect = 4e-05 Identities = 49/127 (38%), Positives = 62/127 (48%), Gaps = 24/127 (18%) Query: 101 SRRGPPPRRYGGGGYGRRSRSP---RRRRRSR--------SRSRS--RSRSRSRSRYSRS 147 SR P RR RSR+P RRR RSR SRSRS R RSRSR R+ Sbjct: 2008 SRTSPVTRRRS------RSRTPPAIRRRSRSRTPLLPRKRSRSRSPLAIRRRSRSRTPRT 2061 Query: 148 KSRSRTRSRSRSTSKSRSARRSKS-KSSSVSRSRSRSRSRSRSRSPPPVSKRESKSRSRS 206 R+ +RS + RSA S S +S S + +R+ S SR+ PPV+ S+ S Sbjct: 2062 ARGKRSLTRSPPAIRRRSASGSSSDRSRSATPPATRNHSGSRT---PPVALNSSRMSCFS 2118 Query: 207 KSPPKSP 213 + P SP Sbjct: 2119 R-PSMSP 2124 Score = 43.9 bits (102), Expect = 1e-04 Identities = 46/123 (37%), Positives = 63/123 (51%), Gaps = 18/123 (14%) Query: 116 GRRSRSPRRRRRSRSRSRS---RSRSRSRSRYSRSKSRSRTRSRSRS------TSKSR-S 165 G+RSRS + S S RS S S S S++K+R+ R RSRS SKSR S Sbjct: 1534 GQRSRSGSSQELDVKPSASPQERSESDS-SPDSKAKTRTPLRQRSRSGSSPEVDSKSRLS 1592 Query: 166 ARRSKSKSSSVSRSRSRSRSRSRS---RSPPPVSKR----ESKSRSRSKSPPKSPEEEGA 218 RRS+S SS + + R+ R++S SP P + +SRS S S + P EG+ Sbjct: 1593 PRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGS 1652 Query: 219 VSS 221 S+ Sbjct: 1653 SST 1655 Score = 40.4 bits (93), Expect = 0.001 Identities = 32/94 (34%), Positives = 38/94 (40%) Query: 117 RRSRSPRRRRRSRSRSRSRSRSRSRSRYSRSKSRSRTRSRSRSTSKSRSARRSKSKSSSV 176 +R SP + R R RS S S + S S S+S S S+ S S SSS Sbjct: 2577 KRVPSPTPAPKEAVREGRPPEPTPAKRKRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2636 Query: 177 SRSRSRSRSRSRSRSPPPVSKRESKSRSRSKSPP 210 S S S S S S P + K S K PP Sbjct: 2637 SSSSSSSSSSSSPSPAKPGPQALPKPASPKKPPP 2670 Score = 40.0 bits (92), Expect = 0.002 Identities = 35/102 (34%), Positives = 44/102 (43%), Gaps = 14/102 (13%) Query: 101 SRRGPPPRRYGGGGYGRRSRSPRRRRRSRSRSRSRSRSRSRSRYSRSKSRSRTRSRSRST 160 S + PPP RRSRSPR+ S SRS S S R + R + S S Sbjct: 2664 SPKKPPPGE-------RRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQPSPRDQQSSSSE 2716 Query: 161 SKSRSARRSKSKSSSVSRSRSRSRSRSRSRSPPPVSKRESKS 202 SR +R S+S S R R + SP P+ R S+S Sbjct: 2717 RGSRRGQRGDSRSPSHKR-------RRETPSPRPMRHRSSRS 2751 Score = 39.3 bits (90), Expect = 0.003 Identities = 39/114 (34%), Positives = 55/114 (48%), Gaps = 13/114 (11%) Query: 117 RRSRSPRRRRRSRSRSRSRSRSRSRSRYSRSKSRSRTRSRSRSTS--------KSRSARR 168 R SP + + R RS S S S ++ +R+ RSRS S + R Sbjct: 1498 RSPSSPELNNKCLTPQRERSGSES-SVDQKTVARTPLGQRSRSGSSQELDVKPSASPQER 1556 Query: 169 SKSKSSSVSRSRSRS--RSRSRSRSPPPV--SKRESKSRSRSKSPPKSPEEEGA 218 S+S SS S++++R+ R RSRS S P V R S RSRS S P+ ++ A Sbjct: 1557 SESDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRA 1610 Score = 38.1 bits (87), Expect = 0.006 Identities = 45/139 (32%), Positives = 54/139 (38%), Gaps = 20/139 (14%) Query: 94 RPPDSHHSRRGPPPRRYGGGGYGRRSRSPRRRRRSRSRSRSRSRSRSRSRYSRSKSRSRT 153 R P H PPR +S +P R+ SRS S S RS S S + Sbjct: 884 RTPSRHSCSGSSPPRV--------KSSTPPRQSPSRSSSPQPKVKAIISPRQRSHSGSSS 935 Query: 154 RSRSRSTSKSRSAR-RSKSKSSSVSRSRSRSRSRSRSRSP-----PPVSKRESKSRSRSK 207 S SR TS++ R RS S S+V S S S SP P R+S S S S Sbjct: 936 PSPSRVTSRTTPRRSRSVSPCSNVESRLLPRYSHSGSSSPDTKVKPETPPRQSHSGSISP 995 Query: 208 SP------PKSPEEEGAVS 220 P P P G+ S Sbjct: 996 YPKVKAQTPPGPSLSGSKS 1014 Score = 38.1 bits (87), Expect = 0.006 Identities = 30/93 (32%), Positives = 40/93 (43%), Gaps = 1/93 (1%) Query: 120 RSPRRRRRSRSRSRSRSRSRSRSRYSRSKSRSRTRSRSRSTSKSR-SARRSKSKSSSVSR 178 R+P R R S + S R+ RS+S S R S + SR S S + R Sbjct: 1412 RTPSRERSSSASSPEMKDGLPRTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPR 1471 Query: 179 SRSRSRSRSRSRSPPPVSKRESKSRSRSKSPPK 211 + SR RS S P + + RSRS S P+ Sbjct: 1472 TPSRGRSECDSSPEPKALPQTPRPRSRSPSSPE 1504 Score = 36.6 bits (83), Expect = 0.017 Identities = 30/92 (32%), Positives = 46/92 (50%), Gaps = 6/92 (6%) Query: 120 RSPRRRRRSRSRSRSRSRSRSRSRYSRSKSRSRTRSRSRSTSKSRSARRSKSKSSSVSRS 179 R+P RR RS S R S + SR+S S S + R+ S+ RS S + ++ ++ Sbjct: 1433 RTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEPKALPQT 1492 Query: 180 RSRSRSRSRSRSPPPVSKR---ESKSRSRSKS 208 R RSRS S P ++ + + RS S+S Sbjct: 1493 ---PRPRSRSPSSPELNNKCLTPQRERSGSES 1521 Score = 36.2 bits (82), Expect = 0.023 Identities = 39/137 (28%), Positives = 54/137 (39%), Gaps = 21/137 (15%) Query: 98 SHHSRRGPPPR-RYGGGGYGRRSRS---------PRRRRRSRSRSRSRSRSRSRSRYSRS 147 S SR G P R G G R S S PR R RS S ++ + R Sbjct: 1436 SRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRTPSRGRSECDSSPEPKALPQTPRP 1495 Query: 148 KSRS----RTRSRSRSTSKSRSARRSKSKSSSVSRSRSRSRSRSRSR-------SPPPVS 196 +SRS ++ + + RS S +V+R+ RSRS S S P Sbjct: 1496 RSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDVKPSASPQE 1555 Query: 197 KRESKSRSRSKSPPKSP 213 + ES S SK+ ++P Sbjct: 1556 RSESDSSPDSKAKTRTP 1572 Score = 35.8 bits (81), Expect = 0.030 Identities = 38/128 (29%), Positives = 56/128 (43%), Gaps = 14/128 (10%) Query: 100 HSRRGPPPRRYGGGGYGRRSRS----PRRRRRSRSRSR----SRSRSRSRSRYSRSKSRS 151 H P +R +RSRS P+ RR RS S S SRSRSR + +K+ + Sbjct: 229 HRSPTPKSKRKSKDKKRKRSRSTTPAPKSRRAHRSTSADSASSSDTSRSRSRSAAAKTHT 288 Query: 152 RT-RSRSRSTSKSR----SARRSKSKSSSVSRSRSRSRSRSRSRSPPPVSKRESKSRSRS 206 RS S + R A S+ ++S R S + + SP ++ K +S + Sbjct: 289 TALAGRSPSPASGRRGEGDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSAT 348 Query: 207 KSPPKSPE 214 + P SPE Sbjct: 349 R-PSPSPE 355 Score = 35.4 bits (80), Expect = 0.039 Identities = 30/82 (36%), Positives = 39/82 (47%), Gaps = 6/82 (7%) Query: 117 RRSRSP--RRRRRSRSRSRS----RSRSRSRSRYSRSKSRSRTRSRSRSTSKSRSARRSK 170 RRSRS R R RS +RS R RS S S RS+S + +R+ S S++ + Sbjct: 2052 RRSRSRTPRTARGKRSLTRSPPAIRRRSASGSSSDRSRSATPPATRNHSGSRTPPVALNS 2111 Query: 171 SKSSSVSRSRSRSRSRSRSRSP 192 S+ S SR R RSP Sbjct: 2112 SRMSCFSRPSMSPTPLDRCRSP 2133 Score = 35.0 bits (79), Expect = 0.051 Identities = 26/63 (41%), Positives = 30/63 (47%), Gaps = 1/63 (1%) Query: 156 RSRSTSKSRSARRSKSKSSSVSRSRSRSRSRSRSRSPPPVSKRESKSRSRSKSP-PKSPE 214 RS S+S S S+ S S SSS S S S S S S PV + R S +P PK Sbjct: 2531 RSSSSSSSSSSSSSSSSSSSSSSSSSGSSSSDSEGSSLPVQPEVALKRVPSPTPAPKEAV 2590 Query: 215 EEG 217 EG Sbjct: 2591 REG 2593 Score = 34.7 bits (78), Expect = 0.066 Identities = 21/58 (36%), Positives = 30/58 (51%) Query: 148 KSRSRTRSRSRSTSKSRSARRSKSKSSSVSRSRSRSRSRSRSRSPPPVSKRESKSRSR 205 K +S+T RS + S R+S S+S S+ S RSRS PV++ S+S R Sbjct: 1058 KGQSQTSPDHRSDTSSPEVRQSHSESPSLQSKSQTSPKGGRSRSSSPVTELASRSPIR 1115 Score = 31.6 bits (70), Expect = 0.56 Identities = 31/127 (24%), Positives = 48/127 (37%), Gaps = 12/127 (9%) Query: 93 GRPPDSHHSRRGPPPRRYGGGGYGRRSRSPRRRRRSRSRSRSRSRSRSRSRYSRSKSRSR 152 GR P RRG G + + +R S + + S + K +S Sbjct: 293 GRSPSPASGRRGE-----GDAPFSEPGTTSTQRPSSPETATKQPSSPYEDKDKDKKEKSA 347 Query: 153 TRSRSRSTSKSRSARRSKSKSSSVSRSRSRSRSRSRSRSPP----PVSKRESKSRSRSKS 208 TR S S RS+ + + + + S + P PV+ S +R +S Sbjct: 348 TRP---SPSPERSSTGPEPPAPTPLLAERHGGSPQPLATTPLSQEPVNPPSEASPTRDRS 404 Query: 209 PPKSPEE 215 PPKSPE+ Sbjct: 405 PPKSPEK 411 Score = 30.8 bits (68), Expect = 0.96 Identities = 32/106 (30%), Positives = 48/106 (45%), Gaps = 6/106 (5%) Query: 116 GRRSRS---PRRRRRSRSRSRSRSRSRSRS-RYSRSKSRSRTRSRSRSTSKSRSARRSKS 171 G+RS + P RRRS S S S RSRS + +R+ S SRT + ++S+ R Sbjct: 2064 GKRSLTRSPPAIRRRSASGS-SSDRSRSATPPATRNHSGSRTPPVALNSSRMSCFSRPSM 2122 Query: 172 KSSSVSRSRSRSRSRSRSRSPPPVSKRESKSRSRSKSP-PKSPEEE 216 + + R RS S P+S + S P P+ P+ + Sbjct: 2123 SPTPLDRCRSPGMLEPLGSSRTPMSVLQQAGGSMMDGPGPRIPDHQ 2168 Score = 30.8 bits (68), Expect = 0.96 Identities = 48/168 (28%), Positives = 57/168 (33%), Gaps = 48/168 (28%) Query: 88 QMARYGRPPDSHHSRRGPPPRRYGGGGYGRRSRSPRRRRRSRSRSRSRSRSRSRSRYSRS 147 + R GRPP+ ++R RR S S S S S S S S S S S S Sbjct: 2588 EAVREGRPPEPTPAKR---KRRSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSSS 2644 Query: 148 KSRS-------------------------RTRS-----------RSRSTSKSRSARRS-- 169 S S R+RS RS S S R S Sbjct: 2645 SSSSPSPAKPGPQALPKPASPKKPPPGERRSRSPRKPIDSLRDSRSLSYSPVERRRPSPQ 2704 Query: 170 ---KSKSSSVSRSRSRSRSRSRSRSPPPVSKRESKS----RSRSKSPP 210 + + SS S SR R SRSP +RE+ S R RS P Sbjct: 2705 PSPRDQQSSSSERGSRRGQRGDSRSPSHKRRRETPSPRPMRHRSSRSP 2752 >gi|38146113 arginine/serine-rich coiled-coil 2 isoform b [Homo sapiens] Length = 375 Score = 79.0 bits (193), Expect = 3e-15 Identities = 52/116 (44%), Positives = 62/116 (53%), Gaps = 10/116 (8%) Query: 99 HHSRRGPPPRRYGGGGYGRRSRSPRRRRRSRSRSRSRSRSRSRSRYSRSKSRSRTRSRSR 158 H S +G G R R R+ R RS SRSRSR R SR + +SR+RSR R Sbjct: 34 HSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRER 93 Query: 159 STSKSRSARRSKSKSSSV-------SRSRSRSRSRSRSRSPPPVSKRESKSRSRSK 207 S+SRS R KS+S S SRSRSRSR R R+RS S+ S+SR R K Sbjct: 94 KKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSR---SRTRSRSRDRKK 146 Score = 78.2 bits (191), Expect = 5e-15 Identities = 55/154 (35%), Positives = 77/154 (50%), Gaps = 5/154 (3%) Query: 52 KESRGFAFVRFHDKRDAEDAMDAMDGAVLDGRELRVQMARYGRPPDSHHSRRGPPPRRYG 111 K S+ +DK + D + +G + + R SH R R Sbjct: 19 KSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRERRHRS 78 Query: 112 GGGYGRRSRS-PRRRRRSRSRSR----SRSRSRSRSRYSRSKSRSRTRSRSRSTSKSRSA 166 ++SRS R R++SRSRSR SRSRSR R R RS+SRSR+R R R+ S+SR+ Sbjct: 79 RSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRTR 138 Query: 167 RRSKSKSSSVSRSRSRSRSRSRSRSPPPVSKRES 200 RS+ + + + R SRS SR+ SPPP R + Sbjct: 139 SRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNT 172 Score = 76.6 bits (187), Expect = 2e-14 Identities = 46/97 (47%), Positives = 61/97 (62%), Gaps = 6/97 (6%) Query: 123 RRRRRSRSRSRSRSRSRSRSRYSRSKSRSRTRSRSRSTSKSRSARRSKSKSSSVSRSRSR 182 R +R+ R SR RS SRSRSR R +SRSR R +SRS S+ R RS+S+ SRSRSR Sbjct: 52 RHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSR 111 Query: 183 SRS---RSRSRSPPPVSKRESKSRSRSKSPPKSPEEE 216 R RSRSRS S+ ++RSRS++ +S + + Sbjct: 112 ERKRRIRSRSRSR---SRHRHRTRSRSRTRSRSRDRK 145 Score = 73.9 bits (180), Expect = 1e-13 Identities = 52/105 (49%), Positives = 62/105 (59%), Gaps = 13/105 (12%) Query: 118 RSRSPRRRRRSRSRSRSRSRSRSRSRYSRSKSRSRTRSRSRSTSKSRS-----ARRSKSK 172 R RS R R R RSRSR R +SR SRS+ R ++RSRSR KSRS RR +S+ Sbjct: 62 RGRSHSRSRSRERRHRSRSRERKKSR-SRSRERKKSRSRSRERKKSRSRSRERKRRIRSR 120 Query: 173 SSSVSRSRSRSRSRSRSRSPPPVSK-------RESKSRSRSKSPP 210 S S SR R R+RSRSR+RS K R S+S SR+ SPP Sbjct: 121 SRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPP 165 Score = 54.3 bits (129), Expect = 8e-08 Identities = 32/84 (38%), Positives = 39/84 (46%) Query: 129 RSRSRSRSRSRSRSRYSRSKSRSRTRSRSRSTSKSRSARRSKSKSSSVSRSRSRSRSRSR 188 R S+ +S + +S K S + R R S R K K SR RS SRSRSR Sbjct: 13 RHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSR 72 Query: 189 SRSPPPVSKRESKSRSRSKSPPKS 212 R S+ KSRSRS+ KS Sbjct: 73 ERRHRSRSRERKKSRSRSRERKKS 96 Score = 52.8 bits (125), Expect = 2e-07 Identities = 28/94 (29%), Positives = 45/94 (47%) Query: 123 RRRRRSRSRSRSRSRSRSRSRYSRSKSRSRTRSRSRSTSKSRSARRSKSKSSSVSRSRSR 182 ++ RR S+ +S + +S + S + R R S+ + K + SS RS SR Sbjct: 9 KQGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSR 68 Query: 183 SRSRSRSRSPPPVSKRESKSRSRSKSPPKSPEEE 216 SRSR R +++S+SRSR + +S E Sbjct: 69 SRSRERRHRSRSRERKKSRSRSRERKKSRSRSRE 102 Score = 51.2 bits (121), Expect = 7e-07 Identities = 33/102 (32%), Positives = 53/102 (51%), Gaps = 7/102 (6%) Query: 112 GGGYGRRSRSPRRRRRSRSRSRSRSRSRSRSRYSRSKS-RSRTRSRSRSTSKSRSARRSK 170 G + + +S ++ + + S + R R + S++ R + + R +S+ RS RS+ Sbjct: 11 GRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSR 70 Query: 171 SKSSSVSRSRSRSRSRSRSRSPPPVSKRESKSRSRSKSPPKS 212 S+ RSRSR R +SRSRS + KSRSRS+ KS Sbjct: 71 SRERR-HRSRSRERKKSRSRS-----RERKKSRSRSRERKKS 106 Score = 50.4 bits (119), Expect = 1e-06 Identities = 29/93 (31%), Positives = 41/93 (44%) Query: 124 RRRRSRSRSRSRSRSRSRSRYSRSKSRSRTRSRSRSTSKSRSARRSKSKSSSVSRSRSRS 183 RR S+ +S + +S + S + R R S + R R+ + S S SRSRS Sbjct: 12 RRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRS 71 Query: 184 RSRSRSRSPPPVSKRESKSRSRSKSPPKSPEEE 216 R R K S+SR R KS +S E + Sbjct: 72 RERRHRSRSRERKKSRSRSRERKKSRSRSRERK 104 >gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo sapiens] Length = 434 Score = 79.0 bits (193), Expect = 3e-15 Identities = 52/116 (44%), Positives = 62/116 (53%), Gaps = 10/116 (8%) Query: 99 HHSRRGPPPRRYGGGGYGRRSRSPRRRRRSRSRSRSRSRSRSRSRYSRSKSRSRTRSRSR 158 H S +G G R R R+ R RS SRSRSR R SR + +SR+RSR R Sbjct: 93 HSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRER 152 Query: 159 STSKSRSARRSKSKSSSV-------SRSRSRSRSRSRSRSPPPVSKRESKSRSRSK 207 S+SRS R KS+S S SRSRSRSR R R+RS S+ S+SR R K Sbjct: 153 KKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSR---SRTRSRSRDRKK 205 Score = 78.2 bits (191), Expect = 5e-15 Identities = 55/154 (35%), Positives = 77/154 (50%), Gaps = 5/154 (3%) Query: 52 KESRGFAFVRFHDKRDAEDAMDAMDGAVLDGRELRVQMARYGRPPDSHHSRRGPPPRRYG 111 K S+ +DK + D + +G + + R SH R R Sbjct: 78 KSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRERRHRS 137 Query: 112 GGGYGRRSRS-PRRRRRSRSRSR----SRSRSRSRSRYSRSKSRSRTRSRSRSTSKSRSA 166 ++SRS R R++SRSRSR SRSRSR R R RS+SRSR+R R R+ S+SR+ Sbjct: 138 RSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRTR 197 Query: 167 RRSKSKSSSVSRSRSRSRSRSRSRSPPPVSKRES 200 RS+ + + + R SRS SR+ SPPP R + Sbjct: 198 SRSRDRKKRIEKPRRFSRSLSRTPSPPPFRGRNT 231 Score = 76.6 bits (187), Expect = 2e-14 Identities = 46/97 (47%), Positives = 61/97 (62%), Gaps = 6/97 (6%) Query: 123 RRRRRSRSRSRSRSRSRSRSRYSRSKSRSRTRSRSRSTSKSRSARRSKSKSSSVSRSRSR 182 R +R+ R SR RS SRSRSR R +SRSR R +SRS S+ R RS+S+ SRSRSR Sbjct: 111 RHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSR 170 Query: 183 SRS---RSRSRSPPPVSKRESKSRSRSKSPPKSPEEE 216 R RSRSRS S+ ++RSRS++ +S + + Sbjct: 171 ERKRRIRSRSRSR---SRHRHRTRSRSRTRSRSRDRK 204 Score = 73.9 bits (180), Expect = 1e-13 Identities = 52/105 (49%), Positives = 62/105 (59%), Gaps = 13/105 (12%) Query: 118 RSRSPRRRRRSRSRSRSRSRSRSRSRYSRSKSRSRTRSRSRSTSKSRS-----ARRSKSK 172 R RS R R R RSRSR R +SR SRS+ R ++RSRSR KSRS RR +S+ Sbjct: 121 RGRSHSRSRSRERRHRSRSRERKKSR-SRSRERKKSRSRSRERKKSRSRSRERKRRIRSR 179 Query: 173 SSSVSRSRSRSRSRSRSRSPPPVSK-------RESKSRSRSKSPP 210 S S SR R R+RSRSR+RS K R S+S SR+ SPP Sbjct: 180 SRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSRSLSRTPSPP 224 Score = 61.2 bits (147), Expect = 7e-10 Identities = 40/104 (38%), Positives = 50/104 (48%), Gaps = 8/104 (7%) Query: 117 RRSRSPRRRRRSRSRSRSRSRSRSRSRYSRS--------KSRSRTRSRSRSTSKSRSARR 168 R+S + R+ RSRSRS+ R S+ + S+ K S + R R S R Sbjct: 52 RKSDNEGRKHRSRSRSKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDR 111 Query: 169 SKSKSSSVSRSRSRSRSRSRSRSPPPVSKRESKSRSRSKSPPKS 212 K K SR RS SRSRSR R S+ KSRSRS+ KS Sbjct: 112 HKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKS 155 Score = 57.0 bits (136), Expect = 1e-08 Identities = 38/124 (30%), Positives = 55/124 (44%), Gaps = 6/124 (4%) Query: 99 HH---SRRGPPPRRYGGGGYGRRSRSPRRR---RRSRSRSRSRSRSRSRSRYSRSKSRSR 152 HH SR R+ GR+ RS R RR S+ +S + +S + S + Sbjct: 38 HHYSRSRSRSRERKRKSDNEGRKHRSRSRSKEGRRHESKDKSSKKHKSEEHNDKEHSSDK 97 Query: 153 TRSRSRSTSKSRSARRSKSKSSSVSRSRSRSRSRSRSRSPPPVSKRESKSRSRSKSPPKS 212 R R S+ + K + SS RS SRSRSR R +++S+SRSR + +S Sbjct: 98 GRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSRS 157 Query: 213 PEEE 216 E Sbjct: 158 RSRE 161 Score = 39.7 bits (91), Expect = 0.002 Identities = 33/108 (30%), Positives = 42/108 (38%), Gaps = 12/108 (11%) Query: 114 GYGRRSRSPRRRRRSRSRSRSRSRSRSRSRYSRSKSRSRTRSRSRSTSKSRSARRSKSKS 173 G SP R ++ S S S+ YSRS+SRSR R R +S ++ R Sbjct: 10 GLAPEKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKR-KSDNEGRK-------- 60 Query: 174 SSVSRSRSRSRSRSRSRSPPPVSKRESKSRSRSKSPPKSPEEEGAVSS 221 RSRSRS+ R S SK+ K E SS Sbjct: 61 ---HRSRSRSKEGRRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSS 105 >gi|9558733 transformer-2 alpha [Homo sapiens] Length = 282 Score = 77.8 bits (190), Expect = 7e-15 Identities = 68/180 (37%), Positives = 84/180 (46%), Gaps = 26/180 (14%) Query: 2 SYGRPPPDVEGMTSLKVDNLTYRTSPDTLRRVFEKYGRVGDVYIPRDRYTKESRGFAFVR 61 S P P+ T L V L+ T+ LR VF +YG + V + D+ T SRGFAFV Sbjct: 111 SRANPDPN----TCLGVFGLSLYTTERDLREVFSRYGPLSGVNVVYDQRTGRSRGFAFVY 166 Query: 62 FHDKRDAEDAMDAMDGAVLDGRELRVQMA------------RYGRPPDSHHSRRGPPPRR 109 F D+++AM+ +G LDGR +RV + GRP +H G Sbjct: 167 FERIDDSKEAMERANGMELDGRRIRVDYSITKRAHTPTPGIYMGRP--THSGGGGGGGGG 224 Query: 110 YGGGGYGRRSRSPRRRRRSRSRSR-----SRSRSRSRSRYSRSKSRSRTRSRSRSTSKSR 164 GGGG GRR S R R R R R RS S Y SR R+RSRSRS S R Sbjct: 225 GGGGGGGRRRDSYYDRGYDRGYDRYEDYDYRYRRRSPSPY---YSRYRSRSRSRSYSPRR 281 Score = 55.8 bits (133), Expect = 3e-08 Identities = 34/66 (51%), Positives = 44/66 (66%) Query: 143 RYSRSKSRSRTRSRSRSTSKSRSARRSKSKSSSVSRSRSRSRSRSRSRSPPPVSKRESKS 202 R SRS+S+S T + +R S+SRS RS S+ S S S SRSRS+SRSRS +R ++S Sbjct: 12 RESRSQSKSPTGTPARVKSESRSGSRSPSRVSKHSESHSRSRSKSRSRSRRHSHRRYTRS 71 Query: 203 RSRSKS 208 RS S S Sbjct: 72 RSHSHS 77 Score = 55.5 bits (132), Expect = 4e-08 Identities = 46/119 (38%), Positives = 58/119 (48%), Gaps = 17/119 (14%) Query: 81 DGRELRVQMARYGRPPDSHHSRRGPPPR-----RYGGGGYGRRSRSPRRRRRSRSRSRSR 135 +GRE R Q S G P R R G R S+ RSRS+SRSR Sbjct: 10 EGRESRSQSK----------SPTGTPARVKSESRSGSRSPSRVSKHSESHSRSRSKSRSR 59 Query: 136 SRSRSRSRYSRSKSRSRT-RSRSRSTSKSRSARRSKSKSSSVSRSRSRSRSRSRSRSPP 193 SR S RY+RS+S S + R RSRS S + RR +S+S S +R R + SR+ P Sbjct: 60 SRRHSHRRYTRSRSHSHSHRRRSRSRSYTPEYRRRRSRSHSPMSNR-RRHTGSRANPDP 117 Score = 54.7 bits (130), Expect = 6e-08 Identities = 52/116 (44%), Positives = 60/116 (51%), Gaps = 26/116 (22%) Query: 116 GRRSRSPRR-------RRRSRSRSRSRSRSR------SRSRYSRSKSRSRTRSRSRSTSK 162 GR SRS + R +S SRS SRS SR S SR SRSKSRSR+R S Sbjct: 11 GRESRSQSKSPTGTPARVKSESRSGSRSPSRVSKHSESHSR-SRSKSRSRSRRHSH---- 65 Query: 163 SRSARRSKSKSSSVSRSRSRSRS------RSRSRSPPPVSKRESKSRSRSKSPPKS 212 R RS+S S S R RSRSRS R RSRS P+S R + SR+ P + Sbjct: 66 -RRYTRSRSHSHS-HRRRSRSRSYTPEYRRRRSRSHSPMSNRRRHTGSRANPDPNT 119 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.312 0.126 0.352 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 9,343,396 Number of Sequences: 37866 Number of extensions: 434647 Number of successful extensions: 19297 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 702 Number of HSP's successfully gapped in prelim test: 498 Number of HSP's that attempted gapping in prelim test: 4606 Number of HSP's gapped (non-prelim): 5287 length of query: 221 length of database: 18,247,518 effective HSP length: 98 effective length of query: 123 effective length of database: 14,536,650 effective search space: 1788007950 effective search space used: 1788007950 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.9 bits) S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.