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Search of human proteins with 47132557
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|47132557 fibronectin 1 isoform 1 preproprotein [Homo
sapiens]
(2477 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|47132557 fibronectin 1 isoform 1 preproprotein [Homo sapiens] 5150 0.0
gi|47132551 fibronectin 1 isoform 2 preproprotein [Homo sapiens] 5000 0.0
gi|47132555 fibronectin 1 isoform 4 preproprotein [Homo sapiens] 3009 0.0
gi|16933542 fibronectin 1 isoform 3 preproprotein [Homo sapiens] 3002 0.0
gi|47132553 fibronectin 1 isoform 5 preproprotein [Homo sapiens] 2990 0.0
gi|47132549 fibronectin 1 isoform 6 preproprotein [Homo sapiens] 2989 0.0
gi|47132547 fibronectin 1 isoform 7 preproprotein [Homo sapiens] 1440 0.0
gi|93141047 collagen, type XII, alpha 1 long isoform precursor [... 386 e-106
gi|153946395 tenascin C precursor [Homo sapiens] 380 e-105
gi|188528648 tenascin XB isoform 1 precursor [Homo sapiens] 338 4e-92
gi|157384973 tenascin R [Homo sapiens] 329 2e-89
gi|62988324 tenascin N [Homo sapiens] 316 2e-85
gi|93141049 collagen, type XII, alpha 1 short isoform precursor ... 289 2e-77
gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens] 220 1e-56
gi|55743096 collagen, type XIV, alpha 1 [Homo sapiens] 211 7e-54
gi|157952215 protein tyrosine phosphatase, receptor type, B isof... 188 5e-47
gi|157952213 protein tyrosine phosphatase, receptor type, B isof... 188 5e-47
gi|110349719 titin isoform N2-A [Homo sapiens] 175 6e-43
gi|110349717 titin isoform novex-2 [Homo sapiens] 175 6e-43
gi|110349713 titin isoform novex-1 [Homo sapiens] 175 6e-43
gi|110349715 titin isoform N2-B [Homo sapiens] 175 6e-43
gi|119220552 sidekick 1 [Homo sapiens] 166 3e-40
gi|222352127 sidekick 2 [Homo sapiens] 165 5e-40
gi|109633039 protein tyrosine phosphatase, receptor type, F isof... 153 2e-36
gi|112734845 collagen, type XX, alpha 1 [Homo sapiens] 152 5e-36
gi|18860892 protein tyrosine phosphatase, receptor type, D isofo... 149 3e-35
gi|109633041 protein tyrosine phosphatase, receptor type, F isof... 147 1e-34
gi|20665034 tenascin XB isoform 2 [Homo sapiens] 147 2e-34
gi|189217853 matrix metalloproteinase 2 isoform b [Homo sapiens] 146 3e-34
gi|11342666 matrix metalloproteinase 2 isoform a preproprotein [... 146 3e-34
>gi|47132557 fibronectin 1 isoform 1 preproprotein [Homo sapiens]
Length = 2477
Score = 5150 bits (13359), Expect = 0.0
Identities = 2477/2477 (100%), Positives = 2477/2477 (100%)
Query: 1 MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ 60
MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ
Sbjct: 1 MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ 60
Query: 61 INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI 120
INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI
Sbjct: 61 INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI 120
Query: 121 WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK 180
WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK
Sbjct: 121 WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK 180
Query: 181 PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY 240
PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY
Sbjct: 181 PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY 240
Query: 241 RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP 300
RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP
Sbjct: 241 RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP 300
Query: 301 QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC 360
QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC
Sbjct: 301 QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC 360
Query: 361 VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC 420
VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC
Sbjct: 361 VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC 420
Query: 421 HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI 480
HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI
Sbjct: 421 HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI 480
Query: 481 GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM 540
GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM
Sbjct: 481 GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM 540
Query: 541 LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ 600
LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ
Sbjct: 541 LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ 600
Query: 601 PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP 660
PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP
Sbjct: 601 PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP 660
Query: 661 GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP 720
GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP
Sbjct: 661 GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP 720
Query: 721 LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL 780
LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL
Sbjct: 721 LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL 780
Query: 781 LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITG 840
LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITG
Sbjct: 781 LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITG 840
Query: 841 YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG 900
YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG
Sbjct: 841 YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG 900
Query: 901 TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT 960
TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT
Sbjct: 901 TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT 960
Query: 961 FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP 1020
FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP
Sbjct: 961 FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP 1020
Query: 1021 RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG 1080
RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG
Sbjct: 1021 RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG 1080
Query: 1081 VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV 1140
VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV
Sbjct: 1081 VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV 1140
Query: 1141 SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT 1200
SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT
Sbjct: 1141 SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT 1200
Query: 1201 PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS 1260
PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS
Sbjct: 1201 PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS 1260
Query: 1261 DTIIPEVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIFEDFVDSSV 1320
DTIIPEVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIFEDFVDSSV
Sbjct: 1261 DTIIPEVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIFEDFVDSSV 1320
Query: 1321 GYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAP 1380
GYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAP
Sbjct: 1321 GYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAP 1380
Query: 1381 PPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTP 1440
PPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTP
Sbjct: 1381 PPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTP 1440
Query: 1441 LRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHS 1500
LRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHS
Sbjct: 1441 LRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHS 1500
Query: 1501 RNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWD 1560
RNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWD
Sbjct: 1501 RNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWD 1560
Query: 1561 APAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPA 1620
APAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPA
Sbjct: 1561 APAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPA 1620
Query: 1621 SSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKT 1680
SSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKT
Sbjct: 1621 SSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKT 1680
Query: 1681 AGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIK 1740
AGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIK
Sbjct: 1681 AGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIK 1740
Query: 1741 IAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDM 1800
IAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDM
Sbjct: 1741 IAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDM 1800
Query: 1801 ESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEIN 1860
ESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEIN
Sbjct: 1801 ESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEIN 1860
Query: 1861 LAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETT 1920
LAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETT
Sbjct: 1861 LAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETT 1920
Query: 1921 ITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDN 1980
ITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDN
Sbjct: 1921 ITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDN 1980
Query: 1981 ARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVP 2040
ARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVP
Sbjct: 1981 ARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVP 2040
Query: 2041 RPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELPQLVTLPHPNLHGPE 2100
RPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELPQLVTLPHPNLHGPE
Sbjct: 2041 RPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELPQLVTLPHPNLHGPE 2100
Query: 2101 ILDVPSTVQKTPFVTHPGYDTGNGIQLPGTSGQQPSVGQQMIFEEHGFRRTTPPTTATPI 2160
ILDVPSTVQKTPFVTHPGYDTGNGIQLPGTSGQQPSVGQQMIFEEHGFRRTTPPTTATPI
Sbjct: 2101 ILDVPSTVQKTPFVTHPGYDTGNGIQLPGTSGQQPSVGQQMIFEEHGFRRTTPPTTATPI 2160
Query: 2161 RHRPRPYPPNVGEEIQIGHIPREDVDYHLYPHGPGLNPNASTGQEALSQTTISWAPFQDT 2220
RHRPRPYPPNVGEEIQIGHIPREDVDYHLYPHGPGLNPNASTGQEALSQTTISWAPFQDT
Sbjct: 2161 RHRPRPYPPNVGEEIQIGHIPREDVDYHLYPHGPGLNPNASTGQEALSQTTISWAPFQDT 2220
Query: 2221 SEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHKVREEVVT 2280
SEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHKVREEVVT
Sbjct: 2221 SEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHKVREEVVT 2280
Query: 2281 VGNSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSR 2340
VGNSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSR
Sbjct: 2281 VGNSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSR 2340
Query: 2341 WCHDNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEATCYDDGKTYHVGEQWQ 2400
WCHDNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEATCYDDGKTYHVGEQWQ
Sbjct: 2341 WCHDNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEATCYDDGKTYHVGEQWQ 2400
Query: 2401 KEYLGAICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYSQRYHQRTNTNVNCPI 2460
KEYLGAICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYSQRYHQRTNTNVNCPI
Sbjct: 2401 KEYLGAICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYSQRYHQRTNTNVNCPI 2460
Query: 2461 ECFMPLDVQADREDSRE 2477
ECFMPLDVQADREDSRE
Sbjct: 2461 ECFMPLDVQADREDSRE 2477
>gi|47132551 fibronectin 1 isoform 2 preproprotein [Homo sapiens]
Length = 2421
Score = 5000 bits (12969), Expect = 0.0
Identities = 2421/2477 (97%), Positives = 2421/2477 (97%), Gaps = 56/2477 (2%)
Query: 1 MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ 60
MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ
Sbjct: 1 MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ 60
Query: 61 INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI 120
INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI
Sbjct: 61 INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI 120
Query: 121 WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK 180
WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK
Sbjct: 121 WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK 180
Query: 181 PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY 240
PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY
Sbjct: 181 PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY 240
Query: 241 RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP 300
RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP
Sbjct: 241 RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP 300
Query: 301 QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC 360
QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC
Sbjct: 301 QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC 360
Query: 361 VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC 420
VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC
Sbjct: 361 VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC 420
Query: 421 HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI 480
HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI
Sbjct: 421 HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI 480
Query: 481 GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM 540
GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM
Sbjct: 481 GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM 540
Query: 541 LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ 600
LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ
Sbjct: 541 LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ 600
Query: 601 PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP 660
PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP
Sbjct: 601 PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP 660
Query: 661 GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP 720
GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP
Sbjct: 661 GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP 720
Query: 721 LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL 780
LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL
Sbjct: 721 LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL 780
Query: 781 LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITG 840
LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITG
Sbjct: 781 LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITG 840
Query: 841 YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG 900
YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG
Sbjct: 841 YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG 900
Query: 901 TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT 960
TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT
Sbjct: 901 TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT 960
Query: 961 FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP 1020
FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP
Sbjct: 961 FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP 1020
Query: 1021 RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG 1080
RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG
Sbjct: 1021 RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG 1080
Query: 1081 VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV 1140
VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV
Sbjct: 1081 VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV 1140
Query: 1141 SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT 1200
SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT
Sbjct: 1141 SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT 1200
Query: 1201 PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS 1260
PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS
Sbjct: 1201 PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS 1260
Query: 1261 DTIIPEVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIFEDFVDSSV 1320
DTIIPEVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIFEDFVDSSV
Sbjct: 1261 DTIIPEVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIFEDFVDSSV 1320
Query: 1321 GYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAP 1380
GYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAP
Sbjct: 1321 GYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAP 1380
Query: 1381 PPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTP 1440
PPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTP
Sbjct: 1381 PPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTP 1440
Query: 1441 LRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHS 1500
LRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHS
Sbjct: 1441 LRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHS 1500
Query: 1501 RNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWD 1560
RNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWD
Sbjct: 1501 RNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWD 1560
Query: 1561 APAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPA 1620
APAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPA
Sbjct: 1561 APAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPA 1620
Query: 1621 SSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKT 1680
SSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKT
Sbjct: 1621 SSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKT 1680
Query: 1681 AGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIK 1740
AGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIK
Sbjct: 1681 AGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIK 1740
Query: 1741 IAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDM 1800
IAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDM
Sbjct: 1741 IAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDM 1800
Query: 1801 ESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEIN 1860
ESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEIN
Sbjct: 1801 ESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEIN 1860
Query: 1861 LAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETT 1920
LAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETT
Sbjct: 1861 LAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETT 1920
Query: 1921 ITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDN 1980
ITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDN
Sbjct: 1921 ITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDN 1980
Query: 1981 ARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVP 2040
ARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVP
Sbjct: 1981 ARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVP 2040
Query: 2041 RPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELPQLVTLPHPNLHGPE 2100
RPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKT
Sbjct: 2041 RPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKT------------------ 2082
Query: 2101 ILDVPSTVQKTPFVTHPGYDTGNGIQLPGTSGQQPSVGQQMIFEEHGFRRTTPPTTATPI 2160
VQKTPFVTHPGYDTGNGIQLPGTSGQQPSVGQQMIFEEHGFRRTTPPTTATPI
Sbjct: 2083 -------VQKTPFVTHPGYDTGNGIQLPGTSGQQPSVGQQMIFEEHGFRRTTPPTTATPI 2135
Query: 2161 RHRPRPYPPNVGEEIQIGHIPREDVDYHLYPHGPGLNPNASTGQEALSQTTISWAPFQDT 2220
RHRPRPYPPNVG QEALSQTTISWAPFQDT
Sbjct: 2136 RHRPRPYPPNVG-------------------------------QEALSQTTISWAPFQDT 2164
Query: 2221 SEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHKVREEVVT 2280
SEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHKVREEVVT
Sbjct: 2165 SEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHKVREEVVT 2224
Query: 2281 VGNSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSR 2340
VGNSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSR
Sbjct: 2225 VGNSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSR 2284
Query: 2341 WCHDNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEATCYDDGKTYHVGEQWQ 2400
WCHDNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEATCYDDGKTYHVGEQWQ
Sbjct: 2285 WCHDNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEATCYDDGKTYHVGEQWQ 2344
Query: 2401 KEYLGAICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYSQRYHQRTNTNVNCPI 2460
KEYLGAICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYSQRYHQRTNTNVNCPI
Sbjct: 2345 KEYLGAICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYSQRYHQRTNTNVNCPI 2404
Query: 2461 ECFMPLDVQADREDSRE 2477
ECFMPLDVQADREDSRE
Sbjct: 2405 ECFMPLDVQADREDSRE 2421
>gi|47132555 fibronectin 1 isoform 4 preproprotein [Homo sapiens]
Length = 2330
Score = 3009 bits (7800), Expect = 0.0
Identities = 1515/2136 (70%), Positives = 1655/2136 (77%), Gaps = 76/2136 (3%)
Query: 1 MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ 60
MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ
Sbjct: 1 MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ 60
Query: 61 INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI 120
INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI
Sbjct: 61 INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI 120
Query: 121 WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK 180
WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK
Sbjct: 121 WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK 180
Query: 181 PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY 240
PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY
Sbjct: 181 PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY 240
Query: 241 RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP 300
RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP
Sbjct: 241 RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP 300
Query: 301 QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC 360
QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC
Sbjct: 301 QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC 360
Query: 361 VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC 420
VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC
Sbjct: 361 VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC 420
Query: 421 HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI 480
HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI
Sbjct: 421 HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI 480
Query: 481 GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM 540
GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM
Sbjct: 481 GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM 540
Query: 541 LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ 600
LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ
Sbjct: 541 LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ 600
Query: 601 PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP 660
PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP
Sbjct: 601 PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP 660
Query: 661 GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP 720
GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP
Sbjct: 661 GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP 720
Query: 721 LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL 780
LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL
Sbjct: 721 LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL 780
Query: 781 LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITG 840
LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITG
Sbjct: 781 LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITG 840
Query: 841 YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG 900
YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG
Sbjct: 841 YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG 900
Query: 901 TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT 960
TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT
Sbjct: 901 TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT 960
Query: 961 FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP 1020
FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP
Sbjct: 961 FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP 1020
Query: 1021 RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG 1080
RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG
Sbjct: 1021 RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG 1080
Query: 1081 VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV 1140
VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV
Sbjct: 1081 VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV 1140
Query: 1141 SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT 1200
SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT
Sbjct: 1141 SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT 1200
Query: 1201 PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS 1260
PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS
Sbjct: 1201 PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS 1260
Query: 1261 DTIIPEVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIFEDFVDSSV 1320
DTIIP VP TDL F +I ++ + W P S + + + + E + S
Sbjct: 1261 DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSD 1320
Query: 1321 GYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAP 1380
+T L PG +Y +SV ++ ES P Q+T + PT + F++I ++ V W
Sbjct: 1321 NAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIA 1380
Query: 1381 PPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTP 1440
P + +T + +R+ P E + S N++ LTNL PGTEYVVS+ ++ + ES
Sbjct: 1381 PRA-TITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPL 1439
Query: 1441 LRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHS 1500
L G+Q T D P ++ T S + W AP T+ YRI + + +E VP S
Sbjct: 1440 LIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGS 1499
Query: 1501 RNSITLTNLTPGTEYVVSIVALNGREESPL----LIGQQSTVSDVPRDLEVVAATPTSLL 1556
+++ T++ L PG +Y +++ A+ GR +SP + T D P ++V S+
Sbjct: 1500 KSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSIS 1559
Query: 1557 ISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRG 1616
+ W + V YR+T G P + T ++ TI GL+P V+Y ++VYA G
Sbjct: 1560 VKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSG 1619
Query: 1617 DSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVT-TTPKNGPGP 1675
+ S+P+ T ID+P + TDV +SI + W V+ YRVT ++P++G
Sbjct: 1620 E----SQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHE 1675
Query: 1676 TKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVD 1735
G + T ++GL+P EY VSV A + ESQPL+ T T I P L FT V
Sbjct: 1676 LFPAPDGEEDT-AELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVT 1734
Query: 1736 VDSIKIAWESPQGQVSRYRVTYSSPE--DGIHELFPAPDGEEDTAELQGLRPGSEYTVSV 1793
S+ W P Q++ YRV + E + E+ APD + + GL ++Y VSV
Sbjct: 1735 PTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPD--SSSVVVSGLMVATKYEVSV 1792
Query: 1794 VALHDDMESQPLIGTQSTA--IPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKE 1851
AL D + S+P G +T + P + T T T+++ W +TG++V P
Sbjct: 1793 YALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPAN 1852
Query: 1852 KTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRA 1911
P++ + PD S ++GL T Y++ +Y L D S P V+ + P
Sbjct: 1853 GQTPIQR-TIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPV--VIDASTAIDAPSNL 1909
Query: 1912 RVTDATETTITISWRTKTETITGFQVD-AVPANGQTPIQRTIKPDVRSYTITGLQPGTDY 1970
R T ++ +SW+ ITG+ + P + + +P V TITGL+PGT+Y
Sbjct: 1910 RFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEY 1969
Query: 1971 KIYLYTLNDNARSSPVV----------------IDASTAIDAPSNL-------------- 2000
IY+ L +N +S P++ D I P
Sbjct: 1970 TIYVIALKNNQKSEPLIGRKKTVQKTPFVTHPGYDTGNGIQLPGTSGQQPSVGQQMIFEE 2029
Query: 2001 -RFLATTP-----------------------NSLLVSWQPPRARITGYIIKYEKPGSPPR 2036
F TTP + +SW P + + YII G+
Sbjct: 2030 HGFRRTTPPTTATPIRHRPRPYPPNVGQEALSQTTISWAPFQ-DTSEYIISCHPVGTDEE 2088
Query: 2037 EVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQK 2072
+ R T AT+TGL G Y I V ALK+ Q+
Sbjct: 2089 PLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQR 2124
Score = 2356 bits (6106), Expect = 0.0
Identities = 1233/1749 (70%), Positives = 1345/1749 (76%), Gaps = 116/1749 (6%)
Query: 768 LPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAP------------- 814
+P S I L PG Y + I + G Q + TT+ P
Sbjct: 659 IPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPF 718
Query: 815 -----PDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTE-LNLPETANSVTLS 868
+V ++ +S VV W ++G+R+ Y S EG + L+LP TA SV +
Sbjct: 719 SPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIP 778
Query: 869 DLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWT 928
DL PG +Y + +Y + E+ E + ++ +TT +P D +V D + + W+
Sbjct: 779 DLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPD------APPDPTVDQVDDTSIVVRWS 832
Query: 929 PPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKP 988
P++ +TGYR+ P LP + N+ ++ L PGV Y ++AV +ES P
Sbjct: 833 RPQAPITGYRIVYSPSVEGSSTELNLPETANSVT-LSDLQPGVQYNITIYAVEENQESTP 891
Query: 989 LTAQQTTK-------LDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQ 1041
+ QQ T + +P +LQFV TD V + WTPP + +TGYR+ V P +
Sbjct: 892 VVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDV--IPVNLPGE 949
Query: 1042 YNVGPSVSKYP---LRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEV 1098
+ +S+ + L P Y + A+ +ES T TT + + E
Sbjct: 950 HGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNE- 1008
Query: 1099 TETTIVITWTP--APRIGFKLGVRPSQGGEAPRE--VTSDSGSIVVSGLTPGVEYVYTIQ 1154
T++T+++ WTP A G++L V ++ G+ PR+ V + L P EY ++
Sbjct: 1009 TDSTVLVRWTPPRAQITGYRLTVGLTRRGQ-PRQYNVGPSVSKYPLRNLQPASEYTVSLV 1067
Query: 1155 VLRDGQERDAPIVNKVVTPLSPPTNL---HLEANPDTGVLTVSWERSTTPDITGYRITTT 1211
++ QE +P V T L P +++ + E T V+T W T G+++
Sbjct: 1068 AIKGNQE--SPKATGVFTTLQPGSSIPPYNTEVTETTIVIT--W---TPAPRIGFKLGVR 1120
Query: 1212 PTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKE-SVPISDTIIPEVPQL 1270
P+ QG V +D S L+PG+EY ++ ++D +E PI + ++ +
Sbjct: 1121 PS---QGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPP 1177
Query: 1271 TDLSFVDITDSSI-GLRWTPLNSSTIIGYRITVVAA-GEGIPIFEDFVDSSVGYYTVTGL 1328
T+L D+ + + W + I GYRIT G+ E+ V + T L
Sbjct: 1178 TNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNL 1237
Query: 1329 EPGIDYDISVITLINGGESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTN 1388
PG++Y++SV T+ + ES P + T AVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTN
Sbjct: 1238 SPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTN 1297
Query: 1389 FLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTG 1448
FLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTG
Sbjct: 1298 FLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTG 1357
Query: 1449 LDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTN 1508
LDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTN
Sbjct: 1358 LDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTN 1417
Query: 1509 LTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRY 1568
LTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRY
Sbjct: 1418 LTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRY 1477
Query: 1569 YRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISIN 1628
YRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISIN
Sbjct: 1478 YRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISIN 1537
Query: 1629 YRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEM 1688
YRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEM
Sbjct: 1538 YRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEM 1597
Query: 1689 TIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQG 1748
TIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQG
Sbjct: 1598 TIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQG 1657
Query: 1749 QVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGT 1808
QVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGT
Sbjct: 1658 QVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGT 1717
Query: 1809 QSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSV 1868
QSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSV
Sbjct: 1718 QSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSV 1777
Query: 1869 VVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTK 1928
VVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTK
Sbjct: 1778 VVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTK 1837
Query: 1929 TETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVI 1988
TETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVI
Sbjct: 1838 TETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVI 1897
Query: 1989 DASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTE 2048
DASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTE
Sbjct: 1898 DASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTE 1957
Query: 2049 ATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELPQLVTLPHPNLHGPEILDVPSTV 2108
ATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKT V
Sbjct: 1958 ATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKT-------------------------V 1992
Query: 2109 QKTPFVTHPGYDTGNGIQLPGTSGQQPSVGQQMIFEEHGFRRTTPPTTATPIRHRPRPYP 2168
QKTPFVTHPGYDTGNGIQLPGTSGQQPSVGQQMIFEEHGFRRTTPPTTATPIRHRPRPYP
Sbjct: 1993 QKTPFVTHPGYDTGNGIQLPGTSGQQPSVGQQMIFEEHGFRRTTPPTTATPIRHRPRPYP 2052
Query: 2169 PNVGEEIQIGHIPREDVDYHLYPHGPGLNPNASTGQEALSQTTISWAPFQDTSEYIISCH 2228
PNVG QEALSQTTISWAPFQDTSEYIISCH
Sbjct: 2053 PNVG-------------------------------QEALSQTTISWAPFQDTSEYIISCH 2081
Query: 2229 PVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHKVREEVVTVGNSVNEG 2288
PVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHKVREEVVTVGNSVNEG
Sbjct: 2082 PVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHKVREEVVTVGNSVNEG 2141
Query: 2289 LNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHDNGVN 2348
LNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHDNGVN
Sbjct: 2142 LNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHDNGVN 2201
Query: 2349 YKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEATCYDDGKTYHVGEQWQKEYLGAIC 2408
YKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEATCYDDGKTYHVGEQWQKEYLGAIC
Sbjct: 2202 YKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEATCYDDGKTYHVGEQWQKEYLGAIC 2261
Query: 2409 SCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYSQRYHQRTNTNVNCPIECFMPLDV 2468
SCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYSQRYHQRTNTNVNCPIECFMPLDV
Sbjct: 2262 SCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYSQRYHQRTNTNVNCPIECFMPLDV 2321
Query: 2469 QADREDSRE 2477
QADREDSRE
Sbjct: 2322 QADREDSRE 2330
Score = 115 bits (287), Expect = 7e-25
Identities = 57/129 (44%), Positives = 74/129 (57%), Gaps = 5/129 (3%)
Query: 2294 DDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHDNGVNYKIGE 2353
+++CFD YT + Y VGD +ER +S C C+G G G C + CH+ G +YKIG+
Sbjct: 94 EETCFDKYTGNTYRVGDTYERPKDSMI-WDCTCIGAGRGRISCTIANRCHEGGQSYKIGD 152
Query: 2354 KWDRQGE-NGQMMSCTCLGNGKGEFKCDPHEATCYDD--GKTYHVGEQWQKEYLG-AICS 2409
W R E G M+ C CLGNGKGE+ C P C+D G +Y VGE W+K Y G +
Sbjct: 153 TWRRPHETGGYMLECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQGWMMVD 212
Query: 2410 CTCFGGQRG 2418
CTC G G
Sbjct: 213 CTCLGEGSG 221
Score = 115 bits (287), Expect = 7e-25
Identities = 57/129 (44%), Positives = 74/129 (57%), Gaps = 5/129 (3%)
Query: 94 EETCFDKYTGNTYRVGDTYERPKDSMI-WDCTCIGAGRGRISCTIANRCHEGGQSYKIGD 152
+++CFD YT + Y VGD +ER +S C C+G G G C + CH+ G +YKIG+
Sbjct: 2147 DDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHDNGVNYKIGE 2206
Query: 153 TWRRPHETGGYMLECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQGWMMVD 212
W R E G M+ C CLGNGKGE+ C P C+D G +Y VGE W+K Y G +
Sbjct: 2207 KWDRQGE-NGQMMSCTCLGNGKGEFKCDPHEATCYDD--GKTYHVGEQWQKEYLG-AICS 2262
Query: 213 CTCLGEGSG 221
CTC G G
Sbjct: 2263 CTCFGGQRG 2271
Score = 98.6 bits (244), Expect = 7e-20
Identities = 54/172 (31%), Positives = 73/172 (42%), Gaps = 34/172 (19%)
Query: 2277 EVVTVGNSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRC 2336
E V +GN E +P + CFD + Y VG+ WE+ + + C CLG GSG C
Sbjct: 166 ECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITC 225
Query: 2337 DSSRWCHDNG--VNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPH------------ 2382
S C+D +Y+IG+ W ++ G ++ C C GNG+GE+KC+ H
Sbjct: 226 TSRNRCNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGP 285
Query: 2383 ----EATCY----------------DDGKTYHVGEQWQKEYLGAICSCTCFG 2414
A Y D G Y VG QW K CTC G
Sbjct: 286 FTDVRAAVYQPQPHPQPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLG 337
Score = 98.6 bits (244), Expect = 7e-20
Identities = 54/172 (31%), Positives = 73/172 (42%), Gaps = 34/172 (19%)
Query: 166 ECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITC 225
E V +GN E +P + CFD + Y VG+ WE+ + + C CLG GSG C
Sbjct: 2130 EVVTVGNSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRC 2189
Query: 226 TSRNRCNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGP 285
S C+D +Y+IG+ W ++ G ++ C C GNG+GE+KC+ H
Sbjct: 2190 DSSRWCHDNG--VNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPH------------ 2235
Query: 286 FTDVRAAVYQPQPHPQPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLG 337
A Y D G Y VG QW K CTC G
Sbjct: 2236 ----EATCY----------------DDGKTYHVGEQWQKEYLGAICSCTCFG 2267
Score = 90.9 bits (224), Expect = 1e-17
Identities = 40/123 (32%), Positives = 65/123 (52%), Gaps = 8/123 (6%)
Query: 2306 YAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHD----NGVNYKIGEKWDRQGEN 2361
Y +GD+W++ + G + C C+G G G + C + D + + Y + + + ++ E
Sbjct: 478 YRIGDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEE 537
Query: 2362 GQMMSCTCLGNGKGEFKCDPHEATCYDD--GKTYHVGEQWQKEYLGAICSCTCFG-GQRG 2418
G M++CTC G G+G +KCDP + C D G Y +G+ W+K G C C+G G
Sbjct: 538 GHMLNCTCFGQGRGRWKCDPVD-QCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGE 596
Query: 2419 WRC 2421
W C
Sbjct: 597 WHC 599
Score = 90.9 bits (224), Expect = 1e-17
Identities = 40/123 (32%), Positives = 65/123 (52%), Gaps = 8/123 (6%)
Query: 478 YRIGDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEE 537
Y +GD+W++ + G + C C+G G G + C + D + + Y + + + ++ E
Sbjct: 2159 YAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHD----NGVNYKIGEKWDRQGEN 2214
Query: 538 GHMLNCTCFGQGRGRWKCDPVD-QCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGE 596
G M++CTC G G+G +KCDP + C D G Y +G+ W+K G C C+G G
Sbjct: 2215 GQMMSCTCLGNGKGEFKCDPHEATCYDD--GKTYHVGEQWQKEYLGAICSCTCFG-GQRG 2271
Query: 597 WHC 599
W C
Sbjct: 2272 WRC 2274
Score = 88.2 bits (217), Expect = 9e-17
Identities = 45/124 (36%), Positives = 65/124 (52%), Gaps = 7/124 (5%)
Query: 2306 YAVGDEWERMSESG-FKLLCQCLGFGSGHFRCDS-SRWCHDN--GVNYKIGEKWDRQGEN 2361
Y +GD W R E+G + L C CLG G G + C + C D+ G +Y +GE W++ +
Sbjct: 148 YKIGDTWRRPHETGGYMLECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQG 207
Query: 2362 GQMMSCTCLGNGKGEFKCDPHEATCYDDGKT-YHVGEQW-QKEYLGAICSCTCFGGQRG- 2418
M+ CTCLG G G C D +T Y +G+ W +K+ G + C C G RG
Sbjct: 208 WMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGE 267
Query: 2419 WRCD 2422
W+C+
Sbjct: 268 WKCE 271
Score = 88.2 bits (217), Expect = 9e-17
Identities = 45/124 (36%), Positives = 65/124 (52%), Gaps = 7/124 (5%)
Query: 148 YKIGDTWRRPHETGGYMLECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQG 207
Y +GD W R E+G + L C CLG G G + C + C D+ G +Y +GE W++ +
Sbjct: 2159 YAVGDEWERMSESG-FKLLCQCLGFGSGHFRCDS-SRWCHDN--GVNYKIGEKWDRQGEN 2214
Query: 208 WMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGE 267
M+ CTCLG G G C D +T Y +G+ W +K+ G + C C G RG
Sbjct: 2215 GQMMSCTCLGNGKGEFKCDPHEATCYDDGKT-YHVGEQW-QKEYLGAICSCTCFGGQRG- 2271
Query: 268 WKCE 271
W+C+
Sbjct: 2272 WRCD 2275
Score = 79.7 bits (195), Expect = 3e-14
Identities = 37/84 (44%), Positives = 54/84 (64%), Gaps = 5/84 (5%)
Query: 2344 DNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEA---TCYDDGKTYHVGEQWQ 2400
+ GV Y+IG++WD+Q + G MM CTC+GNG+GE+ C + C D TY+V + +
Sbjct: 473 NEGVMYRIGDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFH 532
Query: 2401 KEY-LGAICSCTCFGGQRG-WRCD 2422
K + G + +CTCFG RG W+CD
Sbjct: 533 KRHEEGHMLNCTCFGQGRGRWKCD 556
Score = 79.7 bits (195), Expect = 3e-14
Identities = 37/84 (44%), Positives = 54/84 (64%), Gaps = 5/84 (5%)
Query: 473 NEGVMYRIGDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFH 532
+ GV Y+IG++WD+Q + G MM CTC+GNG+GE+ C + C D TY+V + +
Sbjct: 2197 DNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEA---TCYDDGKTYHVGEQWQ 2253
Query: 533 KRHEEGHMLNCTCFGQGRGRWKCD 556
K + G + +CTCFG RG W+CD
Sbjct: 2254 KEY-LGAICSCTCFGGQRG-WRCD 2275
Score = 63.5 bits (153), Expect = 2e-09
Identities = 32/82 (39%), Positives = 46/82 (56%), Gaps = 7/82 (8%)
Query: 2342 CHDNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPH---EATCYD--DGKTYHVG 2396
C+DNG +Y+I ++W+R G + CTC G +G F C+ E TC+D G TY VG
Sbjct: 52 CYDNGKHYQINQQWERT-YLGNALVCTCYGGSRG-FNCESKPEAEETCFDKYTGNTYRVG 109
Query: 2397 EQWQKEYLGAICSCTCFGGQRG 2418
+ +++ I CTC G RG
Sbjct: 110 DTYERPKDSMIWDCTCIGAGRG 131
Score = 63.5 bits (153), Expect = 2e-09
Identities = 32/82 (39%), Positives = 46/82 (56%), Gaps = 7/82 (8%)
Query: 52 CYDNGKHYQINQQWERT-YLGNALVCTCYGGSRG-FNCESKPEAEETCFDKYTGNTYRVG 109
C+DNG +Y+I ++W+R G + CTC G +G F C+ E TC+D G TY VG
Sbjct: 2195 CHDNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPH---EATCYD--DGKTYHVG 2249
Query: 110 DTYERPKDSMIWDCTCIGAGRG 131
+ +++ I CTC G RG
Sbjct: 2250 EQWQKEYLGAICSCTCFGGQRG 2271
Score = 62.0 bits (149), Expect = 7e-09
Identities = 37/107 (34%), Positives = 49/107 (45%), Gaps = 10/107 (9%)
Query: 2281 VGNSVNE----GLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRC 2336
VGN E +Q D D T Y V D + + E G L C C G G G ++C
Sbjct: 499 VGNGRGEWTCIAYSQLRDQCIVDDIT---YNVNDTFHKRHEEGHMLNCTCFGQGRGRWKC 555
Query: 2337 DSSRWCHDN--GVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDP 2381
D C D+ G Y+IG+ W++ +G C C G G GE+ C P
Sbjct: 556 DPVDQCQDSETGTFYQIGDSWEKY-VHGVRYQCYCYGRGIGEWHCQP 601
Score = 62.0 bits (149), Expect = 7e-09
Identities = 37/107 (34%), Positives = 49/107 (45%), Gaps = 10/107 (9%)
Query: 499 VGNGRGEWTCIAYSQLRDQCIVDDIT---YNVNDTFHKRHEEGHMLNCTCFGQGRGRWKC 555
VGN E +Q D D T Y V D + + E G L C C G G G ++C
Sbjct: 2134 VGNSVNE----GLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRC 2189
Query: 556 DPVDQCQDSETGTFYQIGDSWEKY-VHGVRYQCYCYGRGIGEWHCQP 601
D C D+ G Y+IG+ W++ +G C C G G GE+ C P
Sbjct: 2190 DSSRWCHDN--GVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDP 2234
Score = 57.8 bits (138), Expect = 1e-07
Identities = 24/62 (38%), Positives = 35/62 (56%), Gaps = 6/62 (9%)
Query: 2386 CYDDGKTYHVGEQWQKEYLGAICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYS 2445
CYD+GK Y + +QW++ YLG CTC+GG RG+ C++ +P E T Y +
Sbjct: 52 CYDNGKHYQINQQWERTYLGNALVCTCYGGSRGFNCES------KPEAEETCFDKYTGNT 105
Query: 2446 QR 2447
R
Sbjct: 106 YR 107
Score = 57.8 bits (138), Expect = 1e-07
Identities = 24/62 (38%), Positives = 35/62 (56%), Gaps = 6/62 (9%)
Query: 52 CYDNGKHYQINQQWERTYLGNALVCTCYGGSRGFNCES------KPEAEETCFDKYTGNT 105
CYD+GK Y + +QW++ YLG CTC+GG RG+ C++ +P E T Y +
Sbjct: 2239 CYDDGKTYHVGEQWQKEYLGAICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYS 2298
Query: 106 YR 107
R
Sbjct: 2299 QR 2300
Score = 50.1 bits (118), Expect = 3e-05
Identities = 31/110 (28%), Positives = 42/110 (38%), Gaps = 34/110 (30%)
Query: 2297 CFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDS------------------ 2338
C D T + Y +GD W + G L C C G G G ++C+
Sbjct: 231 CNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVR 290
Query: 2339 ---------------SRWCHDNGVNYKIGEKWDRQGENGQMMSCTCLGNG 2373
D+GV Y +G +W + N QM+ CTCLGNG
Sbjct: 291 AAVYQPQPHPQPPPYGHCVTDSGVVYSVGMQWLKTQGNKQML-CTCLGNG 339
Score = 50.1 bits (118), Expect = 3e-05
Identities = 31/110 (28%), Positives = 42/110 (38%), Gaps = 34/110 (30%)
Query: 231 CNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVR 290
C D T + Y +GD W + G L C C G G G ++C+
Sbjct: 2150 CFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDS------------------ 2191
Query: 291 AAVYQPQPHPQPPPYGHCVTDSGVVYSVGMQWLKTQGNKQML-CTCLGNG 339
D+GV Y +G +W + N QM+ CTCLGNG
Sbjct: 2192 ---------------SRWCHDNGVNYKIGEKWDRQGENGQMMSCTCLGNG 2226
>gi|16933542 fibronectin 1 isoform 3 preproprotein [Homo sapiens]
Length = 2355
Score = 3002 bits (7783), Expect = 0.0
Identities = 1486/1997 (74%), Positives = 1617/1997 (80%), Gaps = 21/1997 (1%)
Query: 1 MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ 60
MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ
Sbjct: 1 MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ 60
Query: 61 INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI 120
INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI
Sbjct: 61 INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI 120
Query: 121 WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK 180
WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK
Sbjct: 121 WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK 180
Query: 181 PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY 240
PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY
Sbjct: 181 PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY 240
Query: 241 RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP 300
RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP
Sbjct: 241 RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP 300
Query: 301 QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC 360
QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC
Sbjct: 301 QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC 360
Query: 361 VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC 420
VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC
Sbjct: 361 VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC 420
Query: 421 HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI 480
HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI
Sbjct: 421 HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI 480
Query: 481 GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM 540
GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM
Sbjct: 481 GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM 540
Query: 541 LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ 600
LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ
Sbjct: 541 LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ 600
Query: 601 PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP 660
PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP
Sbjct: 601 PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP 660
Query: 661 GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP 720
GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP
Sbjct: 661 GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP 720
Query: 721 LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL 780
LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL
Sbjct: 721 LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL 780
Query: 781 LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITG 840
LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITG
Sbjct: 781 LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITG 840
Query: 841 YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG 900
YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG
Sbjct: 841 YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG 900
Query: 901 TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT 960
TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT
Sbjct: 901 TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT 960
Query: 961 FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP 1020
FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP
Sbjct: 961 FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP 1020
Query: 1021 RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG 1080
RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG
Sbjct: 1021 RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG 1080
Query: 1081 VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV 1140
VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV
Sbjct: 1081 VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV 1140
Query: 1141 SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT 1200
SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT
Sbjct: 1141 SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT 1200
Query: 1201 PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS 1260
PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS
Sbjct: 1201 PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS 1260
Query: 1261 DTIIPEVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIFEDFVDSSV 1320
DTIIP VP TDL F +I ++ + W P S + + + + E + S
Sbjct: 1261 DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSD 1320
Query: 1321 GYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAP 1380
+T L PG +Y +SV ++ ES P Q+T + PT + F++I ++ V W
Sbjct: 1321 NAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIA 1380
Query: 1381 PPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTP 1440
P + +T + +R+ P E + S N++ LTNL PGTEYVVS+ ++ + ES
Sbjct: 1381 PRA-TITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPL 1439
Query: 1441 LRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHS 1500
L G+Q T D P ++ T S + W AP T+ YRI + + +E VP S
Sbjct: 1440 LIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGS 1499
Query: 1501 RNSITLTNLTPGTEYVVSIVALNGREESPL----LIGQQSTVSDVPRDLEVVAATPTSLL 1556
+++ T++ L PG +Y +++ A+ GR +SP + T D P ++V S+
Sbjct: 1500 KSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSIS 1559
Query: 1557 ISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRG 1616
+ W + V YR+T G P + T ++ TI GL+P V+Y ++VYA G
Sbjct: 1560 VKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSG 1619
Query: 1617 DSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVT-TTPKNGPGP 1675
+ S+P+ T ID+P + TDV +SI + W V+ YRVT ++P++G
Sbjct: 1620 E----SQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHE 1675
Query: 1676 TKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVD 1735
G + T ++GL+P EY VSV A + ESQPL+ T T I P L FT V
Sbjct: 1676 LFPAPDGEEDT-AELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVT 1734
Query: 1736 VDSIKIAWESPQGQVSRYRVTYSSPE--DGIHELFPAPDGEEDTAELQGLRPGSEYTVSV 1793
S+ W P Q++ YRV + E + E+ APD + + GL ++Y VSV
Sbjct: 1735 PTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPD--SSSVVVSGLMVATKYEVSV 1792
Query: 1794 VALHDDMESQPLIGTQSTA--IPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKE 1851
AL D + S+P G +T + P + T T T+++ W +TG++V P
Sbjct: 1793 YALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPAN 1852
Query: 1852 KTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRA 1911
P++ + PD S ++GL T Y++ +Y L D S P V+ + P
Sbjct: 1853 GQTPIQR-TIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPV--VIDASTAIDAPSNL 1909
Query: 1912 RVTDATETTITISWRTKTETITGFQVD-AVPANGQTPIQRTIKPDVRSYTITGLQPGTDY 1970
R T ++ +SW+ ITG+ + P + + +P V TITGL+PGT+Y
Sbjct: 1910 RFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEY 1969
Query: 1971 KIYLYTLNDNARSSPVV 1987
IY+ L +N +S P++
Sbjct: 1970 TIYVIALKNNQKSEPLI 1986
Score = 2422 bits (6278), Expect = 0.0
Identities = 1258/1749 (71%), Positives = 1370/1749 (78%), Gaps = 91/1749 (5%)
Query: 768 LPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAP------------- 814
+P S I L PG Y + I + G Q + TT+ P
Sbjct: 659 IPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPF 718
Query: 815 -----PDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTE-LNLPETANSVTLS 868
+V ++ +S VV W ++G+R+ Y S EG + L+LP TA SV +
Sbjct: 719 SPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIP 778
Query: 869 DLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWT 928
DL PG +Y + +Y + E+ E + ++ +TT +P D +V D + + W+
Sbjct: 779 DLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPD------APPDPTVDQVDDTSIVVRWS 832
Query: 929 PPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKP 988
P++ +TGYR+ P LP + N+ ++ L PGV Y ++AV +ES P
Sbjct: 833 RPQAPITGYRIVYSPSVEGSSTELNLPETANSVT-LSDLQPGVQYNITIYAVEENQESTP 891
Query: 989 LTAQQTTK-------LDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQ 1041
+ QQ T + +P +LQFV TD V + WTPP + +TGYR+ V P +
Sbjct: 892 VVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDV--IPVNLPGE 949
Query: 1042 YNVGPSVSKYP---LRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEV 1098
+ +S+ + L P Y + A+ +ES T TT + + E
Sbjct: 950 HGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNE- 1008
Query: 1099 TETTIVITWTP--APRIGFKLGVRPSQGGEAPRE--VTSDSGSIVVSGLTPGVEYVYTIQ 1154
T++T+++ WTP A G++L V ++ G+ PR+ V + L P EY ++
Sbjct: 1009 TDSTVLVRWTPPRAQITGYRLTVGLTRRGQ-PRQYNVGPSVSKYPLRNLQPASEYTVSLV 1067
Query: 1155 VLRDGQERDAPIVNKVVTPLSPPTNL---HLEANPDTGVLTVSWERSTTPDITGYRITTT 1211
++ QE +P V T L P +++ + E T V+T W T G+++
Sbjct: 1068 AIKGNQE--SPKATGVFTTLQPGSSIPPYNTEVTETTIVIT--W---TPAPRIGFKLGVR 1120
Query: 1212 PTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKE-SVPISDTIIPEVPQL 1270
P+ QG V +D S L+PG+EY ++ ++D +E PI + ++ +
Sbjct: 1121 PS---QGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPP 1177
Query: 1271 TDLSFVDITDSSI-GLRWTPLNSSTIIGYRITVVAA-GEGIPIFEDFVDSSVGYYTVTGL 1328
T+L D+ + + W + I GYRIT G+ E+ V + T L
Sbjct: 1178 TNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNL 1237
Query: 1329 EPGIDYDISVITLINGGESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTN 1388
PG++Y++SV T+ + ES P + T AVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTN
Sbjct: 1238 SPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTN 1297
Query: 1389 FLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTG 1448
FLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTG
Sbjct: 1298 FLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTG 1357
Query: 1449 LDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTN 1508
LDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTN
Sbjct: 1358 LDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTN 1417
Query: 1509 LTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRY 1568
LTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRY
Sbjct: 1418 LTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRY 1477
Query: 1569 YRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISIN 1628
YRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISIN
Sbjct: 1478 YRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISIN 1537
Query: 1629 YRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEM 1688
YRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEM
Sbjct: 1538 YRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEM 1597
Query: 1689 TIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQG 1748
TIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQG
Sbjct: 1598 TIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQG 1657
Query: 1749 QVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGT 1808
QVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGT
Sbjct: 1658 QVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGT 1717
Query: 1809 QSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSV 1868
QSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSV
Sbjct: 1718 QSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSV 1777
Query: 1869 VVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTK 1928
VVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTK
Sbjct: 1778 VVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTK 1837
Query: 1929 TETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVI 1988
TETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVI
Sbjct: 1838 TETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVI 1897
Query: 1989 DASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTE 2048
DASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTE
Sbjct: 1898 DASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTE 1957
Query: 2049 ATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELPQLVTLPHPNLHGPEILDVPSTV 2108
ATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELPQLVTLPHPNLHGPEILDVPSTV
Sbjct: 1958 ATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELPQLVTLPHPNLHGPEILDVPSTV 2017
Query: 2109 QKTPFVTHPGYDTGNGIQLPGTSGQQPSVGQQMIFEEHGFRRTTPPTTATPIRHRPRPYP 2168
QKTPFVTHPGYDTGNGIQLPGTSGQQPSVGQQMIFEEHGFRRTTPPTTATPIRHRPRPYP
Sbjct: 2018 QKTPFVTHPGYDTGNGIQLPGTSGQQPSVGQQMIFEEHGFRRTTPPTTATPIRHRPRPYP 2077
Query: 2169 PNVGEEIQIGHIPREDVDYHLYPHGPGLNPNASTGQEALSQTTISWAPFQDTSEYIISCH 2228
PNVG QEALSQTTISWAPFQDTSEYIISCH
Sbjct: 2078 PNVG-------------------------------QEALSQTTISWAPFQDTSEYIISCH 2106
Query: 2229 PVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHKVREEVVTVGNSVNEG 2288
PVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHKVREEVVTVGNSVNEG
Sbjct: 2107 PVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHKVREEVVTVGNSVNEG 2166
Query: 2289 LNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHDNGVN 2348
LNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHDNGVN
Sbjct: 2167 LNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHDNGVN 2226
Query: 2349 YKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEATCYDDGKTYHVGEQWQKEYLGAIC 2408
YKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEATCYDDGKTYHVGEQWQKEYLGAIC
Sbjct: 2227 YKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEATCYDDGKTYHVGEQWQKEYLGAIC 2286
Query: 2409 SCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYSQRYHQRTNTNVNCPIECFMPLDV 2468
SCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYSQRYHQRTNTNVNCPIECFMPLDV
Sbjct: 2287 SCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYSQRYHQRTNTNVNCPIECFMPLDV 2346
Query: 2469 QADREDSRE 2477
QADREDSRE
Sbjct: 2347 QADREDSRE 2355
Score = 115 bits (287), Expect = 7e-25
Identities = 57/129 (44%), Positives = 74/129 (57%), Gaps = 5/129 (3%)
Query: 2294 DDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHDNGVNYKIGE 2353
+++CFD YT + Y VGD +ER +S C C+G G G C + CH+ G +YKIG+
Sbjct: 94 EETCFDKYTGNTYRVGDTYERPKDSMI-WDCTCIGAGRGRISCTIANRCHEGGQSYKIGD 152
Query: 2354 KWDRQGE-NGQMMSCTCLGNGKGEFKCDPHEATCYDD--GKTYHVGEQWQKEYLG-AICS 2409
W R E G M+ C CLGNGKGE+ C P C+D G +Y VGE W+K Y G +
Sbjct: 153 TWRRPHETGGYMLECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQGWMMVD 212
Query: 2410 CTCFGGQRG 2418
CTC G G
Sbjct: 213 CTCLGEGSG 221
Score = 115 bits (287), Expect = 7e-25
Identities = 57/129 (44%), Positives = 74/129 (57%), Gaps = 5/129 (3%)
Query: 94 EETCFDKYTGNTYRVGDTYERPKDSMI-WDCTCIGAGRGRISCTIANRCHEGGQSYKIGD 152
+++CFD YT + Y VGD +ER +S C C+G G G C + CH+ G +YKIG+
Sbjct: 2172 DDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHDNGVNYKIGE 2231
Query: 153 TWRRPHETGGYMLECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQGWMMVD 212
W R E G M+ C CLGNGKGE+ C P C+D G +Y VGE W+K Y G +
Sbjct: 2232 KWDRQGE-NGQMMSCTCLGNGKGEFKCDPHEATCYDD--GKTYHVGEQWQKEYLG-AICS 2287
Query: 213 CTCLGEGSG 221
CTC G G
Sbjct: 2288 CTCFGGQRG 2296
Score = 98.6 bits (244), Expect = 7e-20
Identities = 54/172 (31%), Positives = 73/172 (42%), Gaps = 34/172 (19%)
Query: 2277 EVVTVGNSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRC 2336
E V +GN E +P + CFD + Y VG+ WE+ + + C CLG GSG C
Sbjct: 166 ECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITC 225
Query: 2337 DSSRWCHDNG--VNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPH------------ 2382
S C+D +Y+IG+ W ++ G ++ C C GNG+GE+KC+ H
Sbjct: 226 TSRNRCNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGP 285
Query: 2383 ----EATCY----------------DDGKTYHVGEQWQKEYLGAICSCTCFG 2414
A Y D G Y VG QW K CTC G
Sbjct: 286 FTDVRAAVYQPQPHPQPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLG 337
Score = 98.6 bits (244), Expect = 7e-20
Identities = 54/172 (31%), Positives = 73/172 (42%), Gaps = 34/172 (19%)
Query: 166 ECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITC 225
E V +GN E +P + CFD + Y VG+ WE+ + + C CLG GSG C
Sbjct: 2155 EVVTVGNSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRC 2214
Query: 226 TSRNRCNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGP 285
S C+D +Y+IG+ W ++ G ++ C C GNG+GE+KC+ H
Sbjct: 2215 DSSRWCHDNG--VNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPH------------ 2260
Query: 286 FTDVRAAVYQPQPHPQPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLG 337
A Y D G Y VG QW K CTC G
Sbjct: 2261 ----EATCY----------------DDGKTYHVGEQWQKEYLGAICSCTCFG 2292
Score = 90.9 bits (224), Expect = 1e-17
Identities = 40/123 (32%), Positives = 65/123 (52%), Gaps = 8/123 (6%)
Query: 2306 YAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHD----NGVNYKIGEKWDRQGEN 2361
Y +GD+W++ + G + C C+G G G + C + D + + Y + + + ++ E
Sbjct: 478 YRIGDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEE 537
Query: 2362 GQMMSCTCLGNGKGEFKCDPHEATCYDD--GKTYHVGEQWQKEYLGAICSCTCFG-GQRG 2418
G M++CTC G G+G +KCDP + C D G Y +G+ W+K G C C+G G
Sbjct: 538 GHMLNCTCFGQGRGRWKCDPVD-QCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGE 596
Query: 2419 WRC 2421
W C
Sbjct: 597 WHC 599
Score = 90.9 bits (224), Expect = 1e-17
Identities = 40/123 (32%), Positives = 65/123 (52%), Gaps = 8/123 (6%)
Query: 478 YRIGDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEE 537
Y +GD+W++ + G + C C+G G G + C + D + + Y + + + ++ E
Sbjct: 2184 YAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHD----NGVNYKIGEKWDRQGEN 2239
Query: 538 GHMLNCTCFGQGRGRWKCDPVD-QCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGE 596
G M++CTC G G+G +KCDP + C D G Y +G+ W+K G C C+G G
Sbjct: 2240 GQMMSCTCLGNGKGEFKCDPHEATCYDD--GKTYHVGEQWQKEYLGAICSCTCFG-GQRG 2296
Query: 597 WHC 599
W C
Sbjct: 2297 WRC 2299
Score = 88.2 bits (217), Expect = 9e-17
Identities = 45/124 (36%), Positives = 65/124 (52%), Gaps = 7/124 (5%)
Query: 2306 YAVGDEWERMSESG-FKLLCQCLGFGSGHFRCDS-SRWCHDN--GVNYKIGEKWDRQGEN 2361
Y +GD W R E+G + L C CLG G G + C + C D+ G +Y +GE W++ +
Sbjct: 148 YKIGDTWRRPHETGGYMLECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQG 207
Query: 2362 GQMMSCTCLGNGKGEFKCDPHEATCYDDGKT-YHVGEQW-QKEYLGAICSCTCFGGQRG- 2418
M+ CTCLG G G C D +T Y +G+ W +K+ G + C C G RG
Sbjct: 208 WMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGE 267
Query: 2419 WRCD 2422
W+C+
Sbjct: 268 WKCE 271
Score = 88.2 bits (217), Expect = 9e-17
Identities = 45/124 (36%), Positives = 65/124 (52%), Gaps = 7/124 (5%)
Query: 148 YKIGDTWRRPHETGGYMLECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQG 207
Y +GD W R E+G + L C CLG G G + C + C D+ G +Y +GE W++ +
Sbjct: 2184 YAVGDEWERMSESG-FKLLCQCLGFGSGHFRCDS-SRWCHDN--GVNYKIGEKWDRQGEN 2239
Query: 208 WMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGE 267
M+ CTCLG G G C D +T Y +G+ W +K+ G + C C G RG
Sbjct: 2240 GQMMSCTCLGNGKGEFKCDPHEATCYDDGKT-YHVGEQW-QKEYLGAICSCTCFGGQRG- 2296
Query: 268 WKCE 271
W+C+
Sbjct: 2297 WRCD 2300
Score = 79.7 bits (195), Expect = 3e-14
Identities = 37/84 (44%), Positives = 54/84 (64%), Gaps = 5/84 (5%)
Query: 2344 DNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEA---TCYDDGKTYHVGEQWQ 2400
+ GV Y+IG++WD+Q + G MM CTC+GNG+GE+ C + C D TY+V + +
Sbjct: 473 NEGVMYRIGDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFH 532
Query: 2401 KEY-LGAICSCTCFGGQRG-WRCD 2422
K + G + +CTCFG RG W+CD
Sbjct: 533 KRHEEGHMLNCTCFGQGRGRWKCD 556
Score = 79.7 bits (195), Expect = 3e-14
Identities = 37/84 (44%), Positives = 54/84 (64%), Gaps = 5/84 (5%)
Query: 473 NEGVMYRIGDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFH 532
+ GV Y+IG++WD+Q + G MM CTC+GNG+GE+ C + C D TY+V + +
Sbjct: 2222 DNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEA---TCYDDGKTYHVGEQWQ 2278
Query: 533 KRHEEGHMLNCTCFGQGRGRWKCD 556
K + G + +CTCFG RG W+CD
Sbjct: 2279 KEY-LGAICSCTCFGGQRG-WRCD 2300
Score = 63.5 bits (153), Expect = 2e-09
Identities = 32/82 (39%), Positives = 46/82 (56%), Gaps = 7/82 (8%)
Query: 2342 CHDNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPH---EATCYD--DGKTYHVG 2396
C+DNG +Y+I ++W+R G + CTC G +G F C+ E TC+D G TY VG
Sbjct: 52 CYDNGKHYQINQQWERT-YLGNALVCTCYGGSRG-FNCESKPEAEETCFDKYTGNTYRVG 109
Query: 2397 EQWQKEYLGAICSCTCFGGQRG 2418
+ +++ I CTC G RG
Sbjct: 110 DTYERPKDSMIWDCTCIGAGRG 131
Score = 63.5 bits (153), Expect = 2e-09
Identities = 32/82 (39%), Positives = 46/82 (56%), Gaps = 7/82 (8%)
Query: 52 CYDNGKHYQINQQWERT-YLGNALVCTCYGGSRG-FNCESKPEAEETCFDKYTGNTYRVG 109
C+DNG +Y+I ++W+R G + CTC G +G F C+ E TC+D G TY VG
Sbjct: 2220 CHDNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPH---EATCYD--DGKTYHVG 2274
Query: 110 DTYERPKDSMIWDCTCIGAGRG 131
+ +++ I CTC G RG
Sbjct: 2275 EQWQKEYLGAICSCTCFGGQRG 2296
Score = 62.0 bits (149), Expect = 7e-09
Identities = 37/107 (34%), Positives = 49/107 (45%), Gaps = 10/107 (9%)
Query: 2281 VGNSVNE----GLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRC 2336
VGN E +Q D D T Y V D + + E G L C C G G G ++C
Sbjct: 499 VGNGRGEWTCIAYSQLRDQCIVDDIT---YNVNDTFHKRHEEGHMLNCTCFGQGRGRWKC 555
Query: 2337 DSSRWCHDN--GVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDP 2381
D C D+ G Y+IG+ W++ +G C C G G GE+ C P
Sbjct: 556 DPVDQCQDSETGTFYQIGDSWEKY-VHGVRYQCYCYGRGIGEWHCQP 601
Score = 62.0 bits (149), Expect = 7e-09
Identities = 37/107 (34%), Positives = 49/107 (45%), Gaps = 10/107 (9%)
Query: 499 VGNGRGEWTCIAYSQLRDQCIVDDIT---YNVNDTFHKRHEEGHMLNCTCFGQGRGRWKC 555
VGN E +Q D D T Y V D + + E G L C C G G G ++C
Sbjct: 2159 VGNSVNE----GLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRC 2214
Query: 556 DPVDQCQDSETGTFYQIGDSWEKY-VHGVRYQCYCYGRGIGEWHCQP 601
D C D+ G Y+IG+ W++ +G C C G G GE+ C P
Sbjct: 2215 DSSRWCHDN--GVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDP 2259
Score = 57.8 bits (138), Expect = 1e-07
Identities = 24/62 (38%), Positives = 35/62 (56%), Gaps = 6/62 (9%)
Query: 2386 CYDDGKTYHVGEQWQKEYLGAICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYS 2445
CYD+GK Y + +QW++ YLG CTC+GG RG+ C++ +P E T Y +
Sbjct: 52 CYDNGKHYQINQQWERTYLGNALVCTCYGGSRGFNCES------KPEAEETCFDKYTGNT 105
Query: 2446 QR 2447
R
Sbjct: 106 YR 107
Score = 57.8 bits (138), Expect = 1e-07
Identities = 24/62 (38%), Positives = 35/62 (56%), Gaps = 6/62 (9%)
Query: 52 CYDNGKHYQINQQWERTYLGNALVCTCYGGSRGFNCES------KPEAEETCFDKYTGNT 105
CYD+GK Y + +QW++ YLG CTC+GG RG+ C++ +P E T Y +
Sbjct: 2264 CYDDGKTYHVGEQWQKEYLGAICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYS 2323
Query: 106 YR 107
R
Sbjct: 2324 QR 2325
Score = 50.1 bits (118), Expect = 3e-05
Identities = 31/110 (28%), Positives = 42/110 (38%), Gaps = 34/110 (30%)
Query: 2297 CFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDS------------------ 2338
C D T + Y +GD W + G L C C G G G ++C+
Sbjct: 231 CNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVR 290
Query: 2339 ---------------SRWCHDNGVNYKIGEKWDRQGENGQMMSCTCLGNG 2373
D+GV Y +G +W + N QM+ CTCLGNG
Sbjct: 291 AAVYQPQPHPQPPPYGHCVTDSGVVYSVGMQWLKTQGNKQML-CTCLGNG 339
Score = 50.1 bits (118), Expect = 3e-05
Identities = 31/110 (28%), Positives = 42/110 (38%), Gaps = 34/110 (30%)
Query: 231 CNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVR 290
C D T + Y +GD W + G L C C G G G ++C+
Sbjct: 2175 CFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDS------------------ 2216
Query: 291 AAVYQPQPHPQPPPYGHCVTDSGVVYSVGMQWLKTQGNKQML-CTCLGNG 339
D+GV Y +G +W + N QM+ CTCLGNG
Sbjct: 2217 ---------------SRWCHDNGVNYKIGEKWDRQGENGQMMSCTCLGNG 2251
Score = 45.8 bits (107), Expect = 5e-04
Identities = 83/370 (22%), Positives = 138/370 (37%), Gaps = 83/370 (22%)
Query: 1949 QRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVID---ASTAIDAPSNLRFLAT 2005
+ TI + SYTI GL+PG Y+ L ++ D ST+ SN T
Sbjct: 656 EATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGET 715
Query: 2006 TP----------------NSLLVSWQPPRARITGYIIKYE--KPGSPPREV-VPRPRPGV 2046
TP +S +VSW ++G+ ++YE + G P+ + +P
Sbjct: 716 TPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPST---A 772
Query: 2047 TEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKT--------------DELPQLV--T 2090
T I L PG +Y + V + + + ++ +T D+ +V +
Sbjct: 773 TSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWS 832
Query: 2091 LPHPNLHGPEILDVPSTVQKTPFVTHPGYDTGNGIQLPGTSGQQPSVGQQM-IFEEHGFR 2149
P + G I+ PS + + P +T N + L S QP V + I+ +
Sbjct: 833 RPQAPITGYRIVYSPSVEGSSTELNLP--ETANSVTL---SDLQPGVQYNITIYAVEENQ 887
Query: 2150 RTTP-----PTTATPIRHRPRPYPPNVGEEIQIGHIPREDVDYHLYPHGPGLNPNASTGQ 2204
+TP TT TP R P P ++ + +++ +
Sbjct: 888 ESTPVVIQQETTGTP-RSDTVPSPRDL-QFVEVTDV------------------------ 921
Query: 2205 EALSQTTISWAPFQD-TSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIV 2263
+ TI W P + + Y + PV E Q +T A +TGL+ G TY V
Sbjct: 922 ----KVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKV 977
Query: 2264 EALKDQQRHK 2273
A+ + K
Sbjct: 978 FAVSHGRESK 987
Score = 32.7 bits (73), Expect = 4.6
Identities = 29/126 (23%), Positives = 53/126 (42%), Gaps = 20/126 (15%)
Query: 670 GLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVT 729
G +P V GQ + +++G + T+ P T+ + P+ P V E+++
Sbjct: 2041 GQQPSV---GQQMIFEEHGFRR----------TTPPTTATPIRHRPRPYPPNVG-QEALS 2086
Query: 730 EITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVN 789
+ T +SW DT S + + +EP +P T+TS + L G Y +
Sbjct: 2087 QTT-----ISWAPFQDT-SEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNII 2140
Query: 790 VYQISE 795
V + +
Sbjct: 2141 VEALKD 2146
>gi|47132553 fibronectin 1 isoform 5 preproprotein [Homo sapiens]
Length = 2296
Score = 2990 bits (7751), Expect = 0.0
Identities = 1509/2120 (71%), Positives = 1652/2120 (77%), Gaps = 78/2120 (3%)
Query: 1 MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ 60
MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ
Sbjct: 1 MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ 60
Query: 61 INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI 120
INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI
Sbjct: 61 INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI 120
Query: 121 WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK 180
WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK
Sbjct: 121 WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK 180
Query: 181 PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY 240
PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY
Sbjct: 181 PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY 240
Query: 241 RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP 300
RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP
Sbjct: 241 RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP 300
Query: 301 QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC 360
QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC
Sbjct: 301 QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC 360
Query: 361 VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC 420
VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC
Sbjct: 361 VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC 420
Query: 421 HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI 480
HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI
Sbjct: 421 HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI 480
Query: 481 GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM 540
GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM
Sbjct: 481 GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM 540
Query: 541 LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ 600
LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ
Sbjct: 541 LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ 600
Query: 601 PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP 660
PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP
Sbjct: 601 PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP 660
Query: 661 GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP 720
GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP
Sbjct: 661 GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP 720
Query: 721 LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL 780
LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL
Sbjct: 721 LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL 780
Query: 781 LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITG 840
LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITG
Sbjct: 781 LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITG 840
Query: 841 YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG 900
YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG
Sbjct: 841 YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG 900
Query: 901 TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT 960
TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT
Sbjct: 901 TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT 960
Query: 961 FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP 1020
FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP
Sbjct: 961 FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP 1020
Query: 1021 RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG 1080
RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG
Sbjct: 1021 RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG 1080
Query: 1081 VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV 1140
VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV
Sbjct: 1081 VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV 1140
Query: 1141 SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT 1200
SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT
Sbjct: 1141 SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT 1200
Query: 1201 PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS 1260
PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS
Sbjct: 1201 PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS 1260
Query: 1261 DTIIPEVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIFEDFVDSSV 1320
DTIIP VP TDL F +I ++ + W P S + + + + E + S
Sbjct: 1261 DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSD 1320
Query: 1321 GYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAP 1380
+T L PG +Y +SV ++ ES P Q+T + PT + F++I ++ V W
Sbjct: 1321 NAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIA 1380
Query: 1381 PPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTP 1440
P + +T + +R+ P E + S N++ LTNL PGTEYVVS+ ++ + ES
Sbjct: 1381 PRA-TITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPL 1439
Query: 1441 LRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHS 1500
L G+Q T D P ++ T S + W AP T+ YRI + + +E VP S
Sbjct: 1440 LIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGS 1499
Query: 1501 RNSITLTNLTPGTEYVVSIVALNGREESPL----LIGQQSTVSDVPRDLEVVAATPTSLL 1556
+++ T++ L PG +Y +++ A+ GR +SP + T D P ++V S+
Sbjct: 1500 KSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSIS 1559
Query: 1557 ISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRG 1616
+ W + V YR+T G P + T ++ TI GL+P V+Y ++VYA G
Sbjct: 1560 VKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSG 1619
Query: 1617 DSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPT 1676
+ S+P+ T I P+ ++ T V S+S +W P + +TGYRV TPK GP
Sbjct: 1620 E----SQPLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPM 1675
Query: 1677 KTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPL--VQTAVTNIDRPKGLAFTDV 1734
K PD + + + GL +Y VSVYA + S+P V T + N+ P+ TD
Sbjct: 1676 KEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDA 1735
Query: 1735 DVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVV 1794
+I I+W + ++ ++V + P +G + + + + GL+PG++Y + +
Sbjct: 1736 TETTITISWRTKTETITGFQVD-AVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLY 1794
Query: 1795 ALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTG 1854
L+D+ S P++ STAI AP++L+F TP SL W PP ++TGY ++ EK G
Sbjct: 1795 TLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKY---EKPG 1851
Query: 1855 -PMKEI--NLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLE-------- 1903
P +E+ P + ++GL T+Y + V ALK+ S P G T E
Sbjct: 1852 SPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELPQLVTLP 1911
Query: 1904 --NVSPPRRARVTDATETTITISWRTKTETITGFQVDAV----PANGQ------------ 1945
N+ P V + T ++ +T G Q+ P+ GQ
Sbjct: 1912 HPNLHGPEILDVPSTVQKTPFVT-HPGYDTGNGIQLPGTSGQQPSVGQQMIFEEHGFRRT 1970
Query: 1946 ------TPIQ---RTIKPDVRSYTITGLQPGTDYKIYLYT----LNDNARSSPVVIDAST 1992
TPI+ R P+V G P D +LY LN NA + + +T
Sbjct: 1971 TPPTTATPIRHRPRPYPPNVGEEIQIGHIPREDVDYHLYPHGPGLNPNASTGQEALSQTT 2030
Query: 1993 AIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATIT 2052
+SW P + + YII G+ + R T AT+T
Sbjct: 2031 -------------------ISWAPFQ-DTSEYIISCHPVGTDEEPLQFRVPGTSTSATLT 2070
Query: 2053 GLEPGTEYTIYVIALKNNQK 2072
GL G Y I V ALK+ Q+
Sbjct: 2071 GLTRGATYNIIVEALKDQQR 2090
Score = 1788 bits (4630), Expect = 0.0
Identities = 971/1688 (57%), Positives = 1153/1688 (68%), Gaps = 58/1688 (3%)
Query: 829 VRWSRPQ-APITGYRIVYSPSVE-GSSTELNLPETANSVTLSDLQPGVQYNITIYAVEE- 885
++W+ PQ + I+ Y + + P G E +P NS T+ L+PGV Y + ++++
Sbjct: 628 IQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQY 687
Query: 886 -NQESTPVVIQQETTGTPRSDTVPSPRDLQF----------VEVTDVKVTIMWTPPESAV 934
+QE T +T TP + + F E+T + W V
Sbjct: 688 GHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTV 747
Query: 935 TGYRVDVIPVNLPGEHGQRLPI-SRNTFAEVTGLSPGVTYYFKVFAVSH-GRESKPLTAQ 992
+G+RV+ ++ G+ Q L + S T + L PG Y V+ +S G +S L+
Sbjct: 748 SGFRVEY-ELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTS 806
Query: 993 QTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYP 1052
QTT DAP + D++++VRW+ P+A ITGYR+ + G + N+ + +
Sbjct: 807 QTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVT 866
Query: 1053 LRNLQPASEYTVSLVAIKGNQES-PKATGVFTTLQPGSSIPPYN-----TEVTETTIVIT 1106
L +LQP +Y +++ A++ NQES P TT P S P EVT+ + I
Sbjct: 867 LSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIM 926
Query: 1107 WTPAPRI--GFKLGVRPSQ--GGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQER 1162
WTP G+++ V P G R S + V+GL+PGV Y + + + G+E
Sbjct: 927 WTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRE- 985
Query: 1163 DAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTP--DITGYRITTTPTNGQQGNS 1220
P+ + T L PTNL D+ VL V W T P ITGYR+T T ++G
Sbjct: 986 SKPLTAQQTTKLDAPTNLQFVNETDSTVL-VRW---TPPRAQITGYRLTVGLT--RRGQP 1039
Query: 1221 LEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPEVPQLTDLSF-VDIT 1279
+ V S NL P EY VS+ +K ++ES + P + + ++T
Sbjct: 1040 RQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVT 1099
Query: 1280 DSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVI 1339
+++I + WTP + IG+++ V + G E V S G V+GL PG++Y ++
Sbjct: 1100 ETTIVITWTP---APRIGFKLGVRPSQGGEAPRE--VTSDSGSIVVSGLTPGVEYVYTIQ 1154
Query: 1340 TLINGGE-SAPTTLTQQTAVPPPTDLRFTNIGPDT--MRVTWAPPPSIDLTNFLVRYSPV 1396
L +G E AP T + PPT+L PDT + V+W + D+T + + +P
Sbjct: 1155 VLRDGQERDAPIVNKVVTPLSPPTNLHL-EANPDTGVLTVSWERSTTPDITGYRITTTPT 1213
Query: 1397 KNEE-DVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGI 1455
++ + E + ++ NL PG EY VSV +V + ES P+ + PT +
Sbjct: 1214 NGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDL 1273
Query: 1456 DFSDITANSFTVHWIAPRAT-ITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTE 1514
F++I ++ V W P + +T + +R+ P E + S N++ LTNL PGTE
Sbjct: 1274 RFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTE 1333
Query: 1515 YVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYG 1574
YVVS+ ++ + ES L G+Q T D P ++ T S + W AP T+ YRI +
Sbjct: 1334 YVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHH 1393
Query: 1575 ETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEID 1634
+ +E VP S+++ T++ L PG +Y +++ A+ GR +SP S T D
Sbjct: 1394 PEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQS----TVSD 1449
Query: 1635 KPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQ 1694
P ++V S+ + W + V YR+T G P + T ++ TI GL+
Sbjct: 1450 VPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLK 1509
Query: 1695 PTVEYVVSVYAQNPSGES----QPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQV 1750
P V+Y ++VYA G+S +P+ T ID+P + TDV +SI + W V
Sbjct: 1510 PGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPV 1569
Query: 1751 SRYRVTYSSPEDGIHELFPAPDGEEDTA-ELQGLRPGSEYTVSVVALHDDMESQPLIGTQ 1809
+ YRVT ++P++G G + T ++GL+P EY VSV A + ESQPL+ T
Sbjct: 1570 TGYRVT-TTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTA 1628
Query: 1810 STAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVV 1869
T IPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVV
Sbjct: 1629 VTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVV 1688
Query: 1870 VSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKT 1929
VSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKT
Sbjct: 1689 VSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKT 1748
Query: 1930 ETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVID 1989
ETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVID
Sbjct: 1749 ETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVID 1808
Query: 1990 ASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEA 2049
ASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEA
Sbjct: 1809 ASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEA 1868
Query: 2050 TITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELPQLVTLPHPNLHGPEILDVPSTVQ 2109
TITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELPQLVTLPHPNLHGPEILDVPSTVQ
Sbjct: 1869 TITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELPQLVTLPHPNLHGPEILDVPSTVQ 1928
Query: 2110 KTPFVTHPGYDTGNGIQLPGTSGQQPSVGQQMIFEEHGFRRTTPPTTATPIRHRPRPYPP 2169
KTPFVTHPGYDTGNGIQLPGTSGQQPSVGQQMIFEEHGFRRTTPPTTATPIRHRPRPYPP
Sbjct: 1929 KTPFVTHPGYDTGNGIQLPGTSGQQPSVGQQMIFEEHGFRRTTPPTTATPIRHRPRPYPP 1988
Query: 2170 NVGEEIQIGHIPREDVDYHLYPHGPGLNPNASTGQEALSQTTISWAPFQDTSEYIISCHP 2229
NVGEEIQIGHIPREDVDYHLYPHGPGLNPNASTGQEALSQTTISWAPFQDTSEYIISCHP
Sbjct: 1989 NVGEEIQIGHIPREDVDYHLYPHGPGLNPNASTGQEALSQTTISWAPFQDTSEYIISCHP 2048
Query: 2230 VGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHKVREEVVTVGNSVNEGL 2289
VGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHKVREEVVTVGNSVNEGL
Sbjct: 2049 VGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHKVREEVVTVGNSVNEGL 2108
Query: 2290 NQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHDNGVNY 2349
NQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHDNGVNY
Sbjct: 2109 NQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHDNGVNY 2168
Query: 2350 KIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEATCYDDGKTYHVGEQWQKEYLGAICS 2409
KIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEATCYDDGKTYHVGEQWQKEYLGAICS
Sbjct: 2169 KIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEATCYDDGKTYHVGEQWQKEYLGAICS 2228
Query: 2410 CTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYSQRYHQRTNTNVNCPIECFMPLDVQ 2469
CTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYSQRYHQRTNTNVNCPIECFMPLDVQ
Sbjct: 2229 CTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYSQRYHQRTNTNVNCPIECFMPLDVQ 2288
Query: 2470 ADREDSRE 2477
ADREDSRE
Sbjct: 2289 ADREDSRE 2296
Score = 115 bits (287), Expect = 7e-25
Identities = 57/129 (44%), Positives = 74/129 (57%), Gaps = 5/129 (3%)
Query: 2294 DDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHDNGVNYKIGE 2353
+++CFD YT + Y VGD +ER +S C C+G G G C + CH+ G +YKIG+
Sbjct: 94 EETCFDKYTGNTYRVGDTYERPKDSMI-WDCTCIGAGRGRISCTIANRCHEGGQSYKIGD 152
Query: 2354 KWDRQGE-NGQMMSCTCLGNGKGEFKCDPHEATCYDD--GKTYHVGEQWQKEYLG-AICS 2409
W R E G M+ C CLGNGKGE+ C P C+D G +Y VGE W+K Y G +
Sbjct: 153 TWRRPHETGGYMLECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQGWMMVD 212
Query: 2410 CTCFGGQRG 2418
CTC G G
Sbjct: 213 CTCLGEGSG 221
Score = 115 bits (287), Expect = 7e-25
Identities = 57/129 (44%), Positives = 74/129 (57%), Gaps = 5/129 (3%)
Query: 94 EETCFDKYTGNTYRVGDTYERPKDSMI-WDCTCIGAGRGRISCTIANRCHEGGQSYKIGD 152
+++CFD YT + Y VGD +ER +S C C+G G G C + CH+ G +YKIG+
Sbjct: 2113 DDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHDNGVNYKIGE 2172
Query: 153 TWRRPHETGGYMLECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQGWMMVD 212
W R E G M+ C CLGNGKGE+ C P C+D G +Y VGE W+K Y G +
Sbjct: 2173 KWDRQGE-NGQMMSCTCLGNGKGEFKCDPHEATCYDD--GKTYHVGEQWQKEYLG-AICS 2228
Query: 213 CTCLGEGSG 221
CTC G G
Sbjct: 2229 CTCFGGQRG 2237
Score = 98.6 bits (244), Expect = 7e-20
Identities = 54/172 (31%), Positives = 73/172 (42%), Gaps = 34/172 (19%)
Query: 2277 EVVTVGNSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRC 2336
E V +GN E +P + CFD + Y VG+ WE+ + + C CLG GSG C
Sbjct: 166 ECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITC 225
Query: 2337 DSSRWCHDNG--VNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPH------------ 2382
S C+D +Y+IG+ W ++ G ++ C C GNG+GE+KC+ H
Sbjct: 226 TSRNRCNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGP 285
Query: 2383 ----EATCY----------------DDGKTYHVGEQWQKEYLGAICSCTCFG 2414
A Y D G Y VG QW K CTC G
Sbjct: 286 FTDVRAAVYQPQPHPQPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLG 337
Score = 98.6 bits (244), Expect = 7e-20
Identities = 54/172 (31%), Positives = 73/172 (42%), Gaps = 34/172 (19%)
Query: 166 ECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITC 225
E V +GN E +P + CFD + Y VG+ WE+ + + C CLG GSG C
Sbjct: 2096 EVVTVGNSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRC 2155
Query: 226 TSRNRCNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGP 285
S C+D +Y+IG+ W ++ G ++ C C GNG+GE+KC+ H
Sbjct: 2156 DSSRWCHDNG--VNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPH------------ 2201
Query: 286 FTDVRAAVYQPQPHPQPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLG 337
A Y D G Y VG QW K CTC G
Sbjct: 2202 ----EATCY----------------DDGKTYHVGEQWQKEYLGAICSCTCFG 2233
Score = 90.9 bits (224), Expect = 1e-17
Identities = 40/123 (32%), Positives = 65/123 (52%), Gaps = 8/123 (6%)
Query: 2306 YAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHD----NGVNYKIGEKWDRQGEN 2361
Y +GD+W++ + G + C C+G G G + C + D + + Y + + + ++ E
Sbjct: 478 YRIGDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEE 537
Query: 2362 GQMMSCTCLGNGKGEFKCDPHEATCYDD--GKTYHVGEQWQKEYLGAICSCTCFG-GQRG 2418
G M++CTC G G+G +KCDP + C D G Y +G+ W+K G C C+G G
Sbjct: 538 GHMLNCTCFGQGRGRWKCDPVD-QCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGE 596
Query: 2419 WRC 2421
W C
Sbjct: 597 WHC 599
Score = 90.9 bits (224), Expect = 1e-17
Identities = 40/123 (32%), Positives = 65/123 (52%), Gaps = 8/123 (6%)
Query: 478 YRIGDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEE 537
Y +GD+W++ + G + C C+G G G + C + D + + Y + + + ++ E
Sbjct: 2125 YAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHD----NGVNYKIGEKWDRQGEN 2180
Query: 538 GHMLNCTCFGQGRGRWKCDPVD-QCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGE 596
G M++CTC G G+G +KCDP + C D G Y +G+ W+K G C C+G G
Sbjct: 2181 GQMMSCTCLGNGKGEFKCDPHEATCYDD--GKTYHVGEQWQKEYLGAICSCTCFG-GQRG 2237
Query: 597 WHC 599
W C
Sbjct: 2238 WRC 2240
Score = 88.2 bits (217), Expect = 9e-17
Identities = 45/124 (36%), Positives = 65/124 (52%), Gaps = 7/124 (5%)
Query: 2306 YAVGDEWERMSESG-FKLLCQCLGFGSGHFRCDS-SRWCHDN--GVNYKIGEKWDRQGEN 2361
Y +GD W R E+G + L C CLG G G + C + C D+ G +Y +GE W++ +
Sbjct: 148 YKIGDTWRRPHETGGYMLECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQG 207
Query: 2362 GQMMSCTCLGNGKGEFKCDPHEATCYDDGKT-YHVGEQW-QKEYLGAICSCTCFGGQRG- 2418
M+ CTCLG G G C D +T Y +G+ W +K+ G + C C G RG
Sbjct: 208 WMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGE 267
Query: 2419 WRCD 2422
W+C+
Sbjct: 268 WKCE 271
Score = 88.2 bits (217), Expect = 9e-17
Identities = 45/124 (36%), Positives = 65/124 (52%), Gaps = 7/124 (5%)
Query: 148 YKIGDTWRRPHETGGYMLECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQG 207
Y +GD W R E+G + L C CLG G G + C + C D+ G +Y +GE W++ +
Sbjct: 2125 YAVGDEWERMSESG-FKLLCQCLGFGSGHFRCDS-SRWCHDN--GVNYKIGEKWDRQGEN 2180
Query: 208 WMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGE 267
M+ CTCLG G G C D +T Y +G+ W +K+ G + C C G RG
Sbjct: 2181 GQMMSCTCLGNGKGEFKCDPHEATCYDDGKT-YHVGEQW-QKEYLGAICSCTCFGGQRG- 2237
Query: 268 WKCE 271
W+C+
Sbjct: 2238 WRCD 2241
Score = 79.7 bits (195), Expect = 3e-14
Identities = 37/84 (44%), Positives = 54/84 (64%), Gaps = 5/84 (5%)
Query: 2344 DNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEA---TCYDDGKTYHVGEQWQ 2400
+ GV Y+IG++WD+Q + G MM CTC+GNG+GE+ C + C D TY+V + +
Sbjct: 473 NEGVMYRIGDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFH 532
Query: 2401 KEY-LGAICSCTCFGGQRG-WRCD 2422
K + G + +CTCFG RG W+CD
Sbjct: 533 KRHEEGHMLNCTCFGQGRGRWKCD 556
Score = 79.7 bits (195), Expect = 3e-14
Identities = 37/84 (44%), Positives = 54/84 (64%), Gaps = 5/84 (5%)
Query: 473 NEGVMYRIGDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFH 532
+ GV Y+IG++WD+Q + G MM CTC+GNG+GE+ C + C D TY+V + +
Sbjct: 2163 DNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEA---TCYDDGKTYHVGEQWQ 2219
Query: 533 KRHEEGHMLNCTCFGQGRGRWKCD 556
K + G + +CTCFG RG W+CD
Sbjct: 2220 KEY-LGAICSCTCFGGQRG-WRCD 2241
Score = 63.5 bits (153), Expect = 2e-09
Identities = 32/82 (39%), Positives = 46/82 (56%), Gaps = 7/82 (8%)
Query: 2342 CHDNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPH---EATCYD--DGKTYHVG 2396
C+DNG +Y+I ++W+R G + CTC G +G F C+ E TC+D G TY VG
Sbjct: 52 CYDNGKHYQINQQWERT-YLGNALVCTCYGGSRG-FNCESKPEAEETCFDKYTGNTYRVG 109
Query: 2397 EQWQKEYLGAICSCTCFGGQRG 2418
+ +++ I CTC G RG
Sbjct: 110 DTYERPKDSMIWDCTCIGAGRG 131
Score = 63.5 bits (153), Expect = 2e-09
Identities = 32/82 (39%), Positives = 46/82 (56%), Gaps = 7/82 (8%)
Query: 52 CYDNGKHYQINQQWERT-YLGNALVCTCYGGSRG-FNCESKPEAEETCFDKYTGNTYRVG 109
C+DNG +Y+I ++W+R G + CTC G +G F C+ E TC+D G TY VG
Sbjct: 2161 CHDNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPH---EATCYD--DGKTYHVG 2215
Query: 110 DTYERPKDSMIWDCTCIGAGRG 131
+ +++ I CTC G RG
Sbjct: 2216 EQWQKEYLGAICSCTCFGGQRG 2237
Score = 62.0 bits (149), Expect = 7e-09
Identities = 37/107 (34%), Positives = 49/107 (45%), Gaps = 10/107 (9%)
Query: 2281 VGNSVNE----GLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRC 2336
VGN E +Q D D T Y V D + + E G L C C G G G ++C
Sbjct: 499 VGNGRGEWTCIAYSQLRDQCIVDDIT---YNVNDTFHKRHEEGHMLNCTCFGQGRGRWKC 555
Query: 2337 DSSRWCHDN--GVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDP 2381
D C D+ G Y+IG+ W++ +G C C G G GE+ C P
Sbjct: 556 DPVDQCQDSETGTFYQIGDSWEKY-VHGVRYQCYCYGRGIGEWHCQP 601
Score = 62.0 bits (149), Expect = 7e-09
Identities = 37/107 (34%), Positives = 49/107 (45%), Gaps = 10/107 (9%)
Query: 499 VGNGRGEWTCIAYSQLRDQCIVDDIT---YNVNDTFHKRHEEGHMLNCTCFGQGRGRWKC 555
VGN E +Q D D T Y V D + + E G L C C G G G ++C
Sbjct: 2100 VGNSVNE----GLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRC 2155
Query: 556 DPVDQCQDSETGTFYQIGDSWEKY-VHGVRYQCYCYGRGIGEWHCQP 601
D C D+ G Y+IG+ W++ +G C C G G GE+ C P
Sbjct: 2156 DSSRWCHDN--GVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDP 2200
Score = 57.8 bits (138), Expect = 1e-07
Identities = 24/62 (38%), Positives = 35/62 (56%), Gaps = 6/62 (9%)
Query: 2386 CYDDGKTYHVGEQWQKEYLGAICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYS 2445
CYD+GK Y + +QW++ YLG CTC+GG RG+ C++ +P E T Y +
Sbjct: 52 CYDNGKHYQINQQWERTYLGNALVCTCYGGSRGFNCES------KPEAEETCFDKYTGNT 105
Query: 2446 QR 2447
R
Sbjct: 106 YR 107
Score = 57.8 bits (138), Expect = 1e-07
Identities = 24/62 (38%), Positives = 35/62 (56%), Gaps = 6/62 (9%)
Query: 52 CYDNGKHYQINQQWERTYLGNALVCTCYGGSRGFNCES------KPEAEETCFDKYTGNT 105
CYD+GK Y + +QW++ YLG CTC+GG RG+ C++ +P E T Y +
Sbjct: 2205 CYDDGKTYHVGEQWQKEYLGAICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYS 2264
Query: 106 YR 107
R
Sbjct: 2265 QR 2266
Score = 50.1 bits (118), Expect = 3e-05
Identities = 31/110 (28%), Positives = 42/110 (38%), Gaps = 34/110 (30%)
Query: 2297 CFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDS------------------ 2338
C D T + Y +GD W + G L C C G G G ++C+
Sbjct: 231 CNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVR 290
Query: 2339 ---------------SRWCHDNGVNYKIGEKWDRQGENGQMMSCTCLGNG 2373
D+GV Y +G +W + N QM+ CTCLGNG
Sbjct: 291 AAVYQPQPHPQPPPYGHCVTDSGVVYSVGMQWLKTQGNKQML-CTCLGNG 339
Score = 50.1 bits (118), Expect = 3e-05
Identities = 31/110 (28%), Positives = 42/110 (38%), Gaps = 34/110 (30%)
Query: 231 CNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVR 290
C D T + Y +GD W + G L C C G G G ++C+
Sbjct: 2116 CFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDS------------------ 2157
Query: 291 AAVYQPQPHPQPPPYGHCVTDSGVVYSVGMQWLKTQGNKQML-CTCLGNG 339
D+GV Y +G +W + N QM+ CTCLGNG
Sbjct: 2158 ---------------SRWCHDNGVNYKIGEKWDRQGENGQMMSCTCLGNG 2192
>gi|47132549 fibronectin 1 isoform 6 preproprotein [Homo sapiens]
Length = 2176
Score = 2989 bits (7749), Expect = 0.0
Identities = 1479/1992 (74%), Positives = 1612/1992 (80%), Gaps = 32/1992 (1%)
Query: 1 MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ 60
MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ
Sbjct: 1 MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ 60
Query: 61 INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI 120
INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI
Sbjct: 61 INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI 120
Query: 121 WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK 180
WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK
Sbjct: 121 WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK 180
Query: 181 PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY 240
PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY
Sbjct: 181 PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY 240
Query: 241 RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP 300
RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP
Sbjct: 241 RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP 300
Query: 301 QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC 360
QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC
Sbjct: 301 QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC 360
Query: 361 VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC 420
VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC
Sbjct: 361 VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC 420
Query: 421 HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI 480
HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI
Sbjct: 421 HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI 480
Query: 481 GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM 540
GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM
Sbjct: 481 GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM 540
Query: 541 LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ 600
LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ
Sbjct: 541 LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ 600
Query: 601 PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP 660
PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP
Sbjct: 601 PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP 660
Query: 661 GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP 720
GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP
Sbjct: 661 GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP 720
Query: 721 LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL 780
LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL
Sbjct: 721 LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL 780
Query: 781 LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITG 840
LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITG
Sbjct: 781 LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITG 840
Query: 841 YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG 900
YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG
Sbjct: 841 YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG 900
Query: 901 TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT 960
TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT
Sbjct: 901 TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT 960
Query: 961 FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP 1020
FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP
Sbjct: 961 FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP 1020
Query: 1021 RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG 1080
RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG
Sbjct: 1021 RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG 1080
Query: 1081 VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV 1140
VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV
Sbjct: 1081 VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV 1140
Query: 1141 SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT 1200
SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT
Sbjct: 1141 SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT 1200
Query: 1201 PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS 1260
PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS
Sbjct: 1201 PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS 1260
Query: 1261 DTIIPEVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIFEDFVDSSV 1320
DTIIP VP TDL F +I ++ + W P S + + + + E + S
Sbjct: 1261 DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSD 1320
Query: 1321 GYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAP 1380
+T L PG +Y +SV ++ ES P Q+T + PT + F++I ++ V W
Sbjct: 1321 NAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIA 1380
Query: 1381 PPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTP 1440
P + +T + +R+ P E + S N++ LTNL PGTEYVVS+ ++ + ES
Sbjct: 1381 PRA-TITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPL 1439
Query: 1441 LRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHS 1500
L G+Q T D P ++ T S + W AP T+ YRI + + +E VP S
Sbjct: 1440 LIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGS 1499
Query: 1501 RNSITLTNLTPGTEYVVSIVALNGREESPL----LIGQQSTVSDVPRDLEVVAATPTSLL 1556
+++ T++ L PG +Y +++ A+ GR +SP + T D P ++V S+
Sbjct: 1500 KSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSIS 1559
Query: 1557 ISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRG 1616
+ W + V YR+T G P + T ++ TI GL+P V+Y ++VYA G
Sbjct: 1560 VKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSG 1619
Query: 1617 DSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPT 1676
+ S+P+ T I P+ ++ T V S+S +W P + +TGYRV TPK GP
Sbjct: 1620 E----SQPLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPM 1675
Query: 1677 KTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPL--VQTAVTNIDRPKGLAFTDV 1734
K PD + + + GL +Y VSVYA + S+P V T + N+ P+ TD
Sbjct: 1676 KEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDA 1735
Query: 1735 DVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVV 1794
+I I+W + ++ ++V + P +G + + + + GL+PG++Y + +
Sbjct: 1736 TETTITISWRTKTETITGFQVD-AVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLY 1794
Query: 1795 ALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTG 1854
L+D+ S P++ STAI AP++L+F TP SL W PP ++TGY ++ EK G
Sbjct: 1795 TLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKY---EKPG 1851
Query: 1855 -PMKEI--NLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRA 1911
P +E+ P + ++GL T+Y + V ALK+ S P G R
Sbjct: 1852 SPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIG------------RK 1899
Query: 1912 RVTDATETTITISWRTKTETITGFQVDAVP-ANGQTPIQRTIKPDVRSYTITGLQPGTDY 1970
+ + TISW +T + + + P + P+Q + S T+TGL G Y
Sbjct: 1900 KTGQEALSQTTISWAPFQDT-SEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATY 1958
Query: 1971 KIYLYTLNDNAR 1982
I + L D R
Sbjct: 1959 NIIVEALKDQQR 1970
Score = 1038 bits (2685), Expect = 0.0
Identities = 636/1617 (39%), Positives = 872/1617 (53%), Gaps = 132/1617 (8%)
Query: 925 IMWTPPE-SAVTGYRVDVIPVNLPGEHGQR-LPISRNTFAEVTGLSPGVTYYFKVFAVS- 981
I W P+ S ++ Y + P N G + +P N++ + GL PGV Y ++ ++
Sbjct: 628 IQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYT-IKGLKPGVVYEGQLISIQQ 686
Query: 982 HGRE------------SKPLTAQQTTKLDAP------TNLQFVNETDSTVLVRWTPPRAQ 1023
+G + S P+T+ T P T+ T S+ +V W
Sbjct: 687 YGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDT 746
Query: 1024 ITGYRLTVGLTRRGQPRQYNVGPSVS-KYPLRNLQPASEYTVSLVAIKGNQESPKATGVF 1082
++G+R+ L+ G QY PS + + +L P +Y V++ I + E
Sbjct: 747 VSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTS 806
Query: 1083 TTLQPGSSIPPYNTEVTETTIVITWT--PAPRIGFKLGVRPS-QGGEAPREVTSDSGSIV 1139
T P + P +V +T+IV+ W+ AP G+++ PS +G + + S+
Sbjct: 807 QTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVT 866
Query: 1140 VSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVT------PLSPPTNLHLEANPDTGVLTV 1193
+S L PGV+Y TI + + QE ++ + T + P +L D V T+
Sbjct: 867 LSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKV-TI 925
Query: 1194 SWERSTTPD--ITGYRITTTPTN--GQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYT 1249
W T P+ +TGYR+ P N G+ G L + + LSPG+ Y V+
Sbjct: 926 MW---TPPESAVTGYRVDVIPVNLPGEHGQRLPI---SRNTFAEVTGLSPGVTYYFKVFA 979
Query: 1250 VKDDKESVPISDTIIPEVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGEGI 1309
V +ES P++ ++ T+L FV+ TDS++ +RWTP + I GYR+TV G
Sbjct: 980 VSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQ-ITGYRLTVGLTRRGQ 1038
Query: 1310 PIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAP------TTLTQQTAVPPPTD 1363
P + V SV Y + L+P +Y +S++ I G + +P TTL +++PP
Sbjct: 1039 PRQYN-VGPSVSKYPLRNLQPASEYTVSLVA-IKGNQESPKATGVFTTLQPGSSIPPYN- 1095
Query: 1364 LRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGT 1423
T + T+ +TW P P I F + P + E A ++ ++V++ L PG
Sbjct: 1096 ---TEVTETTIVITWTPAPRI---GFKLGVRPSQGGE--APREVTSDSGSIVVSGLTPGV 1147
Query: 1424 EYVVSVSSVYE-QHESTPLRGRQKTGLDSPTGIDF-SDITANSFTVHWIAPRAT---ITG 1478
EYV ++ + + Q P+ + T L PT + ++ TV W R+T ITG
Sbjct: 1148 EYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSW--ERSTTPDITG 1205
Query: 1479 YRIRHHPEHFS-GRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQST 1537
YRI P + G E+ V ++S T NL+PG EY VS+ + +ES +
Sbjct: 1206 YRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIP 1265
Query: 1538 VSDVPRDLEVVAATPTSLLISW-DAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATI 1596
P DL P ++ ++W P++ + + + Y V E ++ S + +
Sbjct: 1266 AVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVL 1325
Query: 1597 SGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPS 1656
+ L PG +Y ++V +V + +S P+ +T +D P+ + +D+ NS +V W+
Sbjct: 1326 TNLLPGTEYVVSVSSVYEQHEST----PLRGRQKTGLDSPTGIDFSDITANSFTVHWIAP 1381
Query: 1657 SSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLV 1716
+ +TGYR+ P++ G + + +T+ L P EYVVS+ A N ES L+
Sbjct: 1382 RATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLI 1441
Query: 1717 QTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSP--EDGIHELFPAPDGE 1774
T D P+ L S+ I+W++P V YR+TY + E F P G
Sbjct: 1442 GQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQE-FTVP-GS 1499
Query: 1775 EDTAELQGLRPGSEYTVSVVAL----HDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLS 1830
+ TA + GL+PG +YT++V A+ S+P+ T I P+ ++ T V S+S
Sbjct: 1500 KSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSIS 1559
Query: 1831 AQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTL 1890
+W P + +TGYRV TPK GP K PD + + + GL +Y VSVYA +
Sbjct: 1560 VKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSG 1619
Query: 1891 TSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQR 1950
S+P V T + + P + T T T+++ W +TG++V P P++
Sbjct: 1620 ESQPL--VQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKE 1677
Query: 1951 -TIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPV--VIDASTAIDAPSNLRFLATTP 2007
+ PD S ++GL T Y++ +Y L D S P V+ + P R T
Sbjct: 1678 INLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATE 1737
Query: 2008 NSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIAL 2067
++ +SW+ ITG+ + P + + +P V TITGL+PGT+Y IY+ L
Sbjct: 1738 TTITISWRTKTETITGFQVD-AVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTL 1796
Query: 2068 KNNQKSEPLIGRKKTDELPQLVTLPHPNLHGPEILDVPSTVQKTPFVTHPGYDTGNGIQL 2127
+N +S P++ + +D PS ++ F+ T N + +
Sbjct: 1797 NDNARSSPVV------------------IDASTAIDAPSNLR---FLA----TTPNSLLV 1831
Query: 2128 PGTSGQQPSVGQQMIFEEHGFRRTTPPTTATPIRHRPRPYPPNVGEEIQIGHIPREDVDY 2187
+ G + +E+ G +PP P RPRP V E G P +Y
Sbjct: 1832 SWQPPRARITGYIIKYEKPG----SPPREVVP---RPRP---GVTEATITGLEP--GTEY 1879
Query: 2188 HLYPHGPGLNPNAS-------TGQEALSQTTISWAPFQDTSEYIISCHPVGTDEEPLQFR 2240
+Y N + TGQEALSQTTISWAPFQDTSEYIISCHPVGTDEEPLQFR
Sbjct: 1880 TIYVIALKNNQKSEPLIGRKKTGQEALSQTTISWAPFQDTSEYIISCHPVGTDEEPLQFR 1939
Query: 2241 VPGTSTSATLTGLTRGATYNIIVEALKDQQRHKVREEVVTVGNSVNEGLNQPTDDSCFDP 2300
VPGTSTSATLTGLTRGATYNIIVEALKDQQRHKVREEVVTVGNSVNEGLNQPTDDSCFDP
Sbjct: 1940 VPGTSTSATLTGLTRGATYNIIVEALKDQQRHKVREEVVTVGNSVNEGLNQPTDDSCFDP 1999
Query: 2301 YTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHDNGVNYKIGEKWDRQGE 2360
YTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHDNGVNYKIGEKWDRQGE
Sbjct: 2000 YTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHDNGVNYKIGEKWDRQGE 2059
Query: 2361 NGQMMSCTCLGNGKGEFKCDPHEATCYDDGKTYHVGEQWQKEYLGAICSCTCFGGQRGWR 2420
NGQMMSCTCLGNGKGEFKCDPHEATCYDDGKTYHVGEQWQKEYLGAICSCTCFGGQRGWR
Sbjct: 2060 NGQMMSCTCLGNGKGEFKCDPHEATCYDDGKTYHVGEQWQKEYLGAICSCTCFGGQRGWR 2119
Query: 2421 CDNCRRPGGEPSPEGTTGQSYNQYSQRYHQRTNTNVNCPIECFMPLDVQADREDSRE 2477
CDNCRRPGGEPSPEGTTGQSYNQYSQRYHQRTNTNVNCPIECFMPLDVQADREDSRE
Sbjct: 2120 CDNCRRPGGEPSPEGTTGQSYNQYSQRYHQRTNTNVNCPIECFMPLDVQADREDSRE 2176
Score = 115 bits (287), Expect = 7e-25
Identities = 57/129 (44%), Positives = 74/129 (57%), Gaps = 5/129 (3%)
Query: 2294 DDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHDNGVNYKIGE 2353
+++CFD YT + Y VGD +ER +S C C+G G G C + CH+ G +YKIG+
Sbjct: 94 EETCFDKYTGNTYRVGDTYERPKDSMI-WDCTCIGAGRGRISCTIANRCHEGGQSYKIGD 152
Query: 2354 KWDRQGE-NGQMMSCTCLGNGKGEFKCDPHEATCYDD--GKTYHVGEQWQKEYLG-AICS 2409
W R E G M+ C CLGNGKGE+ C P C+D G +Y VGE W+K Y G +
Sbjct: 153 TWRRPHETGGYMLECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQGWMMVD 212
Query: 2410 CTCFGGQRG 2418
CTC G G
Sbjct: 213 CTCLGEGSG 221
Score = 115 bits (287), Expect = 7e-25
Identities = 57/129 (44%), Positives = 74/129 (57%), Gaps = 5/129 (3%)
Query: 94 EETCFDKYTGNTYRVGDTYERPKDSMI-WDCTCIGAGRGRISCTIANRCHEGGQSYKIGD 152
+++CFD YT + Y VGD +ER +S C C+G G G C + CH+ G +YKIG+
Sbjct: 1993 DDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHDNGVNYKIGE 2052
Query: 153 TWRRPHETGGYMLECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQGWMMVD 212
W R E G M+ C CLGNGKGE+ C P C+D G +Y VGE W+K Y G +
Sbjct: 2053 KWDRQGE-NGQMMSCTCLGNGKGEFKCDPHEATCYDD--GKTYHVGEQWQKEYLG-AICS 2108
Query: 213 CTCLGEGSG 221
CTC G G
Sbjct: 2109 CTCFGGQRG 2117
Score = 98.6 bits (244), Expect = 7e-20
Identities = 54/172 (31%), Positives = 73/172 (42%), Gaps = 34/172 (19%)
Query: 2277 EVVTVGNSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRC 2336
E V +GN E +P + CFD + Y VG+ WE+ + + C CLG GSG C
Sbjct: 166 ECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITC 225
Query: 2337 DSSRWCHDNG--VNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPH------------ 2382
S C+D +Y+IG+ W ++ G ++ C C GNG+GE+KC+ H
Sbjct: 226 TSRNRCNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGP 285
Query: 2383 ----EATCY----------------DDGKTYHVGEQWQKEYLGAICSCTCFG 2414
A Y D G Y VG QW K CTC G
Sbjct: 286 FTDVRAAVYQPQPHPQPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLG 337
Score = 98.6 bits (244), Expect = 7e-20
Identities = 54/172 (31%), Positives = 73/172 (42%), Gaps = 34/172 (19%)
Query: 166 ECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITC 225
E V +GN E +P + CFD + Y VG+ WE+ + + C CLG GSG C
Sbjct: 1976 EVVTVGNSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRC 2035
Query: 226 TSRNRCNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGP 285
S C+D +Y+IG+ W ++ G ++ C C GNG+GE+KC+ H
Sbjct: 2036 DSSRWCHDNG--VNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPH------------ 2081
Query: 286 FTDVRAAVYQPQPHPQPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLG 337
A Y D G Y VG QW K CTC G
Sbjct: 2082 ----EATCY----------------DDGKTYHVGEQWQKEYLGAICSCTCFG 2113
Score = 90.9 bits (224), Expect = 1e-17
Identities = 40/123 (32%), Positives = 65/123 (52%), Gaps = 8/123 (6%)
Query: 2306 YAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHD----NGVNYKIGEKWDRQGEN 2361
Y +GD+W++ + G + C C+G G G + C + D + + Y + + + ++ E
Sbjct: 478 YRIGDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEE 537
Query: 2362 GQMMSCTCLGNGKGEFKCDPHEATCYDD--GKTYHVGEQWQKEYLGAICSCTCFG-GQRG 2418
G M++CTC G G+G +KCDP + C D G Y +G+ W+K G C C+G G
Sbjct: 538 GHMLNCTCFGQGRGRWKCDPVD-QCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGE 596
Query: 2419 WRC 2421
W C
Sbjct: 597 WHC 599
Score = 90.9 bits (224), Expect = 1e-17
Identities = 40/123 (32%), Positives = 65/123 (52%), Gaps = 8/123 (6%)
Query: 478 YRIGDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEE 537
Y +GD+W++ + G + C C+G G G + C + D + + Y + + + ++ E
Sbjct: 2005 YAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHD----NGVNYKIGEKWDRQGEN 2060
Query: 538 GHMLNCTCFGQGRGRWKCDPVD-QCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGE 596
G M++CTC G G+G +KCDP + C D G Y +G+ W+K G C C+G G
Sbjct: 2061 GQMMSCTCLGNGKGEFKCDPHEATCYDD--GKTYHVGEQWQKEYLGAICSCTCFG-GQRG 2117
Query: 597 WHC 599
W C
Sbjct: 2118 WRC 2120
Score = 88.2 bits (217), Expect = 9e-17
Identities = 45/124 (36%), Positives = 65/124 (52%), Gaps = 7/124 (5%)
Query: 2306 YAVGDEWERMSESG-FKLLCQCLGFGSGHFRCDS-SRWCHDN--GVNYKIGEKWDRQGEN 2361
Y +GD W R E+G + L C CLG G G + C + C D+ G +Y +GE W++ +
Sbjct: 148 YKIGDTWRRPHETGGYMLECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQG 207
Query: 2362 GQMMSCTCLGNGKGEFKCDPHEATCYDDGKT-YHVGEQW-QKEYLGAICSCTCFGGQRG- 2418
M+ CTCLG G G C D +T Y +G+ W +K+ G + C C G RG
Sbjct: 208 WMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGE 267
Query: 2419 WRCD 2422
W+C+
Sbjct: 268 WKCE 271
Score = 88.2 bits (217), Expect = 9e-17
Identities = 45/124 (36%), Positives = 65/124 (52%), Gaps = 7/124 (5%)
Query: 148 YKIGDTWRRPHETGGYMLECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQG 207
Y +GD W R E+G + L C CLG G G + C + C D+ G +Y +GE W++ +
Sbjct: 2005 YAVGDEWERMSESG-FKLLCQCLGFGSGHFRCDS-SRWCHDN--GVNYKIGEKWDRQGEN 2060
Query: 208 WMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGE 267
M+ CTCLG G G C D +T Y +G+ W +K+ G + C C G RG
Sbjct: 2061 GQMMSCTCLGNGKGEFKCDPHEATCYDDGKT-YHVGEQW-QKEYLGAICSCTCFGGQRG- 2117
Query: 268 WKCE 271
W+C+
Sbjct: 2118 WRCD 2121
Score = 79.7 bits (195), Expect = 3e-14
Identities = 37/84 (44%), Positives = 54/84 (64%), Gaps = 5/84 (5%)
Query: 2344 DNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEA---TCYDDGKTYHVGEQWQ 2400
+ GV Y+IG++WD+Q + G MM CTC+GNG+GE+ C + C D TY+V + +
Sbjct: 473 NEGVMYRIGDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFH 532
Query: 2401 KEY-LGAICSCTCFGGQRG-WRCD 2422
K + G + +CTCFG RG W+CD
Sbjct: 533 KRHEEGHMLNCTCFGQGRGRWKCD 556
Score = 79.7 bits (195), Expect = 3e-14
Identities = 37/84 (44%), Positives = 54/84 (64%), Gaps = 5/84 (5%)
Query: 473 NEGVMYRIGDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFH 532
+ GV Y+IG++WD+Q + G MM CTC+GNG+GE+ C + C D TY+V + +
Sbjct: 2043 DNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEA---TCYDDGKTYHVGEQWQ 2099
Query: 533 KRHEEGHMLNCTCFGQGRGRWKCD 556
K + G + +CTCFG RG W+CD
Sbjct: 2100 KEY-LGAICSCTCFGGQRG-WRCD 2121
Score = 63.5 bits (153), Expect = 2e-09
Identities = 32/82 (39%), Positives = 46/82 (56%), Gaps = 7/82 (8%)
Query: 2342 CHDNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPH---EATCYD--DGKTYHVG 2396
C+DNG +Y+I ++W+R G + CTC G +G F C+ E TC+D G TY VG
Sbjct: 52 CYDNGKHYQINQQWERT-YLGNALVCTCYGGSRG-FNCESKPEAEETCFDKYTGNTYRVG 109
Query: 2397 EQWQKEYLGAICSCTCFGGQRG 2418
+ +++ I CTC G RG
Sbjct: 110 DTYERPKDSMIWDCTCIGAGRG 131
Score = 63.5 bits (153), Expect = 2e-09
Identities = 32/82 (39%), Positives = 46/82 (56%), Gaps = 7/82 (8%)
Query: 52 CYDNGKHYQINQQWERT-YLGNALVCTCYGGSRG-FNCESKPEAEETCFDKYTGNTYRVG 109
C+DNG +Y+I ++W+R G + CTC G +G F C+ E TC+D G TY VG
Sbjct: 2041 CHDNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPH---EATCYD--DGKTYHVG 2095
Query: 110 DTYERPKDSMIWDCTCIGAGRG 131
+ +++ I CTC G RG
Sbjct: 2096 EQWQKEYLGAICSCTCFGGQRG 2117
Score = 62.0 bits (149), Expect = 7e-09
Identities = 37/107 (34%), Positives = 49/107 (45%), Gaps = 10/107 (9%)
Query: 2281 VGNSVNE----GLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRC 2336
VGN E +Q D D T Y V D + + E G L C C G G G ++C
Sbjct: 499 VGNGRGEWTCIAYSQLRDQCIVDDIT---YNVNDTFHKRHEEGHMLNCTCFGQGRGRWKC 555
Query: 2337 DSSRWCHDN--GVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDP 2381
D C D+ G Y+IG+ W++ +G C C G G GE+ C P
Sbjct: 556 DPVDQCQDSETGTFYQIGDSWEKY-VHGVRYQCYCYGRGIGEWHCQP 601
Score = 62.0 bits (149), Expect = 7e-09
Identities = 37/107 (34%), Positives = 49/107 (45%), Gaps = 10/107 (9%)
Query: 499 VGNGRGEWTCIAYSQLRDQCIVDDIT---YNVNDTFHKRHEEGHMLNCTCFGQGRGRWKC 555
VGN E +Q D D T Y V D + + E G L C C G G G ++C
Sbjct: 1980 VGNSVNE----GLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRC 2035
Query: 556 DPVDQCQDSETGTFYQIGDSWEKY-VHGVRYQCYCYGRGIGEWHCQP 601
D C D+ G Y+IG+ W++ +G C C G G GE+ C P
Sbjct: 2036 DSSRWCHDN--GVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDP 2080
Score = 57.8 bits (138), Expect = 1e-07
Identities = 24/62 (38%), Positives = 35/62 (56%), Gaps = 6/62 (9%)
Query: 2386 CYDDGKTYHVGEQWQKEYLGAICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYS 2445
CYD+GK Y + +QW++ YLG CTC+GG RG+ C++ +P E T Y +
Sbjct: 52 CYDNGKHYQINQQWERTYLGNALVCTCYGGSRGFNCES------KPEAEETCFDKYTGNT 105
Query: 2446 QR 2447
R
Sbjct: 106 YR 107
Score = 57.8 bits (138), Expect = 1e-07
Identities = 24/62 (38%), Positives = 35/62 (56%), Gaps = 6/62 (9%)
Query: 52 CYDNGKHYQINQQWERTYLGNALVCTCYGGSRGFNCES------KPEAEETCFDKYTGNT 105
CYD+GK Y + +QW++ YLG CTC+GG RG+ C++ +P E T Y +
Sbjct: 2085 CYDDGKTYHVGEQWQKEYLGAICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYS 2144
Query: 106 YR 107
R
Sbjct: 2145 QR 2146
Score = 50.1 bits (118), Expect = 3e-05
Identities = 31/110 (28%), Positives = 42/110 (38%), Gaps = 34/110 (30%)
Query: 2297 CFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDS------------------ 2338
C D T + Y +GD W + G L C C G G G ++C+
Sbjct: 231 CNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVR 290
Query: 2339 ---------------SRWCHDNGVNYKIGEKWDRQGENGQMMSCTCLGNG 2373
D+GV Y +G +W + N QM+ CTCLGNG
Sbjct: 291 AAVYQPQPHPQPPPYGHCVTDSGVVYSVGMQWLKTQGNKQML-CTCLGNG 339
Score = 50.1 bits (118), Expect = 3e-05
Identities = 31/110 (28%), Positives = 42/110 (38%), Gaps = 34/110 (30%)
Query: 231 CNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVR 290
C D T + Y +GD W + G L C C G G G ++C+
Sbjct: 1996 CFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDS------------------ 2037
Query: 291 AAVYQPQPHPQPPPYGHCVTDSGVVYSVGMQWLKTQGNKQML-CTCLGNG 339
D+GV Y +G +W + N QM+ CTCLGNG
Sbjct: 2038 ---------------SRWCHDNGVNYKIGEKWDRQGENGQMMSCTCLGNG 2072
>gi|47132547 fibronectin 1 isoform 7 preproprotein [Homo sapiens]
Length = 657
Score = 1440 bits (3728), Expect = 0.0
Identities = 647/647 (100%), Positives = 647/647 (100%)
Query: 1 MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ 60
MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ
Sbjct: 1 MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ 60
Query: 61 INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI 120
INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI
Sbjct: 61 INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI 120
Query: 121 WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK 180
WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK
Sbjct: 121 WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK 180
Query: 181 PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY 240
PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY
Sbjct: 181 PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY 240
Query: 241 RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP 300
RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP
Sbjct: 241 RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP 300
Query: 301 QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC 360
QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC
Sbjct: 301 QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC 360
Query: 361 VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC 420
VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC
Sbjct: 361 VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC 420
Query: 421 HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI 480
HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI
Sbjct: 421 HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI 480
Query: 481 GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM 540
GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM
Sbjct: 481 GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM 540
Query: 541 LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ 600
LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ
Sbjct: 541 LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ 600
Query: 601 PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRP 647
PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRP
Sbjct: 601 PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRP 647
Score = 115 bits (287), Expect = 7e-25
Identities = 57/129 (44%), Positives = 74/129 (57%), Gaps = 5/129 (3%)
Query: 2294 DDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHDNGVNYKIGE 2353
+++CFD YT + Y VGD +ER +S C C+G G G C + CH+ G +YKIG+
Sbjct: 94 EETCFDKYTGNTYRVGDTYERPKDSMI-WDCTCIGAGRGRISCTIANRCHEGGQSYKIGD 152
Query: 2354 KWDRQGE-NGQMMSCTCLGNGKGEFKCDPHEATCYDD--GKTYHVGEQWQKEYLG-AICS 2409
W R E G M+ C CLGNGKGE+ C P C+D G +Y VGE W+K Y G +
Sbjct: 153 TWRRPHETGGYMLECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQGWMMVD 212
Query: 2410 CTCFGGQRG 2418
CTC G G
Sbjct: 213 CTCLGEGSG 221
Score = 98.6 bits (244), Expect = 7e-20
Identities = 54/172 (31%), Positives = 73/172 (42%), Gaps = 34/172 (19%)
Query: 2277 EVVTVGNSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRC 2336
E V +GN E +P + CFD + Y VG+ WE+ + + C CLG GSG C
Sbjct: 166 ECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITC 225
Query: 2337 DSSRWCHDNG--VNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPH------------ 2382
S C+D +Y+IG+ W ++ G ++ C C GNG+GE+KC+ H
Sbjct: 226 TSRNRCNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGP 285
Query: 2383 ----EATCY----------------DDGKTYHVGEQWQKEYLGAICSCTCFG 2414
A Y D G Y VG QW K CTC G
Sbjct: 286 FTDVRAAVYQPQPHPQPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLG 337
Score = 90.9 bits (224), Expect = 1e-17
Identities = 40/123 (32%), Positives = 65/123 (52%), Gaps = 8/123 (6%)
Query: 2306 YAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHD----NGVNYKIGEKWDRQGEN 2361
Y +GD+W++ + G + C C+G G G + C + D + + Y + + + ++ E
Sbjct: 478 YRIGDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEE 537
Query: 2362 GQMMSCTCLGNGKGEFKCDPHEATCYDD--GKTYHVGEQWQKEYLGAICSCTCFG-GQRG 2418
G M++CTC G G+G +KCDP + C D G Y +G+ W+K G C C+G G
Sbjct: 538 GHMLNCTCFGQGRGRWKCDPVD-QCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGE 596
Query: 2419 WRC 2421
W C
Sbjct: 597 WHC 599
Score = 88.2 bits (217), Expect = 9e-17
Identities = 45/124 (36%), Positives = 65/124 (52%), Gaps = 7/124 (5%)
Query: 2306 YAVGDEWERMSESG-FKLLCQCLGFGSGHFRCDS-SRWCHDN--GVNYKIGEKWDRQGEN 2361
Y +GD W R E+G + L C CLG G G + C + C D+ G +Y +GE W++ +
Sbjct: 148 YKIGDTWRRPHETGGYMLECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQG 207
Query: 2362 GQMMSCTCLGNGKGEFKCDPHEATCYDDGKT-YHVGEQW-QKEYLGAICSCTCFGGQRG- 2418
M+ CTCLG G G C D +T Y +G+ W +K+ G + C C G RG
Sbjct: 208 WMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGE 267
Query: 2419 WRCD 2422
W+C+
Sbjct: 268 WKCE 271
Score = 79.7 bits (195), Expect = 3e-14
Identities = 37/84 (44%), Positives = 54/84 (64%), Gaps = 5/84 (5%)
Query: 2344 DNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEA---TCYDDGKTYHVGEQWQ 2400
+ GV Y+IG++WD+Q + G MM CTC+GNG+GE+ C + C D TY+V + +
Sbjct: 473 NEGVMYRIGDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFH 532
Query: 2401 KEY-LGAICSCTCFGGQRG-WRCD 2422
K + G + +CTCFG RG W+CD
Sbjct: 533 KRHEEGHMLNCTCFGQGRGRWKCD 556
Score = 63.5 bits (153), Expect = 2e-09
Identities = 32/82 (39%), Positives = 46/82 (56%), Gaps = 7/82 (8%)
Query: 2342 CHDNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPH---EATCYD--DGKTYHVG 2396
C+DNG +Y+I ++W+R G + CTC G +G F C+ E TC+D G TY VG
Sbjct: 52 CYDNGKHYQINQQWERT-YLGNALVCTCYGGSRG-FNCESKPEAEETCFDKYTGNTYRVG 109
Query: 2397 EQWQKEYLGAICSCTCFGGQRG 2418
+ +++ I CTC G RG
Sbjct: 110 DTYERPKDSMIWDCTCIGAGRG 131
Score = 62.0 bits (149), Expect = 7e-09
Identities = 37/107 (34%), Positives = 49/107 (45%), Gaps = 10/107 (9%)
Query: 2281 VGNSVNE----GLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRC 2336
VGN E +Q D D T Y V D + + E G L C C G G G ++C
Sbjct: 499 VGNGRGEWTCIAYSQLRDQCIVDDIT---YNVNDTFHKRHEEGHMLNCTCFGQGRGRWKC 555
Query: 2337 DSSRWCHDN--GVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDP 2381
D C D+ G Y+IG+ W++ +G C C G G GE+ C P
Sbjct: 556 DPVDQCQDSETGTFYQIGDSWEKY-VHGVRYQCYCYGRGIGEWHCQP 601
Score = 57.8 bits (138), Expect = 1e-07
Identities = 24/62 (38%), Positives = 35/62 (56%), Gaps = 6/62 (9%)
Query: 2386 CYDDGKTYHVGEQWQKEYLGAICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYS 2445
CYD+GK Y + +QW++ YLG CTC+GG RG+ C++ +P E T Y +
Sbjct: 52 CYDNGKHYQINQQWERTYLGNALVCTCYGGSRGFNCES------KPEAEETCFDKYTGNT 105
Query: 2446 QR 2447
R
Sbjct: 106 YR 107
Score = 50.1 bits (118), Expect = 3e-05
Identities = 31/110 (28%), Positives = 42/110 (38%), Gaps = 34/110 (30%)
Query: 2297 CFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDS------------------ 2338
C D T + Y +GD W + G L C C G G G ++C+
Sbjct: 231 CNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVR 290
Query: 2339 ---------------SRWCHDNGVNYKIGEKWDRQGENGQMMSCTCLGNG 2373
D+GV Y +G +W + N QM+ CTCLGNG
Sbjct: 291 AAVYQPQPHPQPPPYGHCVTDSGVVYSVGMQWLKTQGNKQML-CTCLGNG 339
>gi|93141047 collagen, type XII, alpha 1 long isoform precursor [Homo
sapiens]
Length = 3063
Score = 386 bits (991), Expect = e-106
Identities = 377/1533 (24%), Positives = 640/1533 (41%), Gaps = 144/1533 (9%)
Query: 628 IQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQY 687
+ W+ P + +Y++ + P G +E T+ G + ++GLK G
Sbjct: 832 LSWSGA-PGKVKQYLVTYTPVAG-GETQEVTVRGDTTNTVLQGLKEG------------- 876
Query: 688 GHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVT-EITASSFVVSWVSASDT 746
T++ + T+ + + GE T + + VT +IT +S W SA
Sbjct: 877 -----TQYALSVTALYASGAGDALFGEGTTLEERGSPQDLVTKDITDTSIGAYWTSAPGM 931
Query: 747 VSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTS 806
V G+RV ++ + + +LP A I +L P KY ++V+ GE + +
Sbjct: 932 VRGYRVSWKSLYDDVDTGEKNLPEDAIHTMIENLQPETKYRISVFATYSSGEGEPLTGDA 991
Query: 807 QTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVT 866
T VD+ + ++ V W + YR+VY P G +P T S
Sbjct: 992 TTELSQDSKTLKVDEETENTMRVTWKPAPGKVVNYRVVYRPHGRGKQMVAKVPPTVTSTV 1051
Query: 867 LSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIM 926
L LQP Y+IT+ + + E ++ +GT S SPR+L+ + T +
Sbjct: 1052 LKRLQPQTTYDITVLPIYKMGEGK----LRQGSGTTAS-RFKSPRNLKTSDPTMSSFRVT 1106
Query: 927 WTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRES 986
W P V GY+V P G+ + + + L G TY VF + G ES
Sbjct: 1107 WEPAPGEVKGYKVTFHPTGDDRRLGELVVGPYDNTVVLEELRAGTTYKVNVFGMFDGGES 1166
Query: 987 KPLTAQQTTKLDAPTNLQFVN---------ETDSTVLV--RWTPPRAQITGYRLTVGLTR 1035
PL Q+ T L T + ++ E D +LV W+ RA R +
Sbjct: 1167 SPLVGQEMTTLSDTTVMPILSSGMECLTRAEADIVLLVDGSWSIGRANFRTVRSFISRI- 1225
Query: 1036 RGQPRQYNVGPSVSKYPLRNLQ--PASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPP 1093
+++GP + L P +E+ ++ K + LQ +++P
Sbjct: 1226 ---VEVFDIGPKRVQIALAQYSGDPRTEWQLNAHRDKKS-----------LLQAVANLP- 1270
Query: 1094 YNTEVTETTIVITWTPAPRIGFKLGVRP--------------SQGGEAPREVTSDSG--- 1136
Y T T + + + + G+RP EAP + D G
Sbjct: 1271 YKGGNTLTGMALNFIRQQNFRTQAGMRPRARKIGVLITDGKSQDDVEAPSKKLKDEGVEL 1330
Query: 1137 -----------SIVVSGLTPGVEYVYTI----QVLRDGQERDAPIVNKVVTP--LSPPTN 1179
+ + P + Y + + R + + N V P L P+N
Sbjct: 1331 FAIGIKNADEVELKMIATDPDDTHAYNVADFESLSRIVDDLTINLCNSVKGPGDLEAPSN 1390
Query: 1180 LHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSP 1239
L + VSW + + Y++ P +G G E V ++S +L P
Sbjct: 1391 LVISERTHRS-FRVSWT-PPSDSVDRYKVEYYPVSG--GKRQEFYVSRMETSTVLKDLKP 1446
Query: 1240 GLEYNVSVYTVKDDKESVPISDTIIPEVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGYR 1299
EY V+VY+V +D+ S P+ T + L+ D+ +++ ++W P+ +T GY
Sbjct: 1447 ETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVVSLNIYDVGPTTMHVQWQPVGGAT--GYI 1504
Query: 1300 ITVVAAGEGIPIF--EDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTA 1357
++ + P E + +V +T L P +Y ++V +++ S P T+ + T
Sbjct: 1505 LSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEPVTVREVTL 1564
Query: 1358 -VPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVL 1416
+P P DL+ ++ TM V W P P + ++VRY EEDV E+ + S+ + L
Sbjct: 1565 PLPRPQDLKLRDVTHSTMNVFWEPVPG-KVRKYIVRYKTP--EEDVKEVEVDRSETSTSL 1621
Query: 1417 TNLLPGTEYVVSVSSVYEQHESTPLRGRQKTG-LDSPTGIDFSDITANSFTVHWIAPRAT 1475
+L T Y VSVS+V+++ ES P+ ++ T + +PT + +++T+ F W +
Sbjct: 1622 KDLFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPAPTNLKITEVTSEGFRGTWDHGASD 1681
Query: 1476 ITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGRE-ESPLLIGQ 1534
++ YRI P S + E + N++ NL P T Y VSI A+ E ES LIG
Sbjct: 1682 VSLYRITWAPFGSSDK-METILNGDENTLVFENLNPNTIYEVSITAIYPDESESDDLIGS 1740
Query: 1535 QSTVSDV--------PRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFT 1586
+ T+ + PR+L+V AT SL + WD + V+ YRITY + G Q T
Sbjct: 1741 ERTLPILTTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQTTT 1800
Query: 1587 VPGSKSTATISGLKPGVDYTITVYAVT-----GRGDSPASSKPISINYRTEIDKPSQMQV 1641
+ G +++ + LKP YTITV ++ GR +KP++ ++V
Sbjct: 1801 IGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNT--------VRNLRV 1852
Query: 1642 TDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEY-- 1699
D ++++V+W + Y++ P G GP + + + LQP Y
Sbjct: 1853 YDPSTSTLNVRWDHAEGNPRQYKLFYAPAAG-GPEELVPIPGNTNYAILRNLQPDTSYTV 1911
Query: 1700 -VVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYS 1758
VV VY + G + +T + + R + + +S+ + W+ G V +YRV YS
Sbjct: 1912 TVVPVYTEGDGGRTSDTGRTLMRGLAR--NVQVYNPTPNSLDVRWDPAPGPVLQYRVVYS 1969
Query: 1759 SPEDGIH--ELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIP-- 1814
P DG E P G L+ L P + Y+V++VAL+ D E P Q +P
Sbjct: 1970 -PVDGTRPSESIVVP-GNTRMVHLERLIPDTLYSVNLVALYSDGEGNPS-PAQGRTLPRS 2026
Query: 1815 APTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDS-SSVVVSGL 1873
P +L+ T SLS W + + YR+ +P P+ E P ++V++ L
Sbjct: 2027 GPRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGD-PIDEYTTVPGRRNNVILQPL 2085
Query: 1874 MVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETIT 1933
T Y+++V A+ + G T+ + PP+ ++D T +SW +
Sbjct: 2086 QPDTPYKITVIAVYEDGDGGHLTGNGRTV-GLLPPQNIHISDEWYTRFRVSWDPSPSPVL 2144
Query: 1934 GFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTA 1993
G+++ P P++ + ++ SYT+ L P T Y + +Y D+ S P+ +T
Sbjct: 2145 GYKIVYKPVGSNEPMEAFVG-EMTSYTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQGTTL 2203
Query: 1994 IDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITG 2053
++L+ ++ V W P RA T Y +K P R R T TG
Sbjct: 2204 YLNVTDLKTYQIGWDTFCVKWSPHRA-ATSYRLKL-SPADGTRGQEITVRGSETSHCFTG 2261
Query: 2054 LEPGTEYTIYVIALKNNQKSEPLIGRKKTDELP 2086
L P T+Y + V N + + ++ T P
Sbjct: 2262 LSPDTDYGVTVFVQTPNLEGPGVSVKEHTTVKP 2294
Score = 297 bits (760), Expect = 1e-79
Identities = 307/1324 (23%), Positives = 527/1324 (39%), Gaps = 86/1324 (6%)
Query: 798 EQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELN 857
EQ L + P P D + +V WS + Y I Y + +
Sbjct: 621 EQELAAIKKKAYVP--PKDLSFSEVTSYGFKTNWSPAGENVFSYHITYKEAAGDDEVTVV 678
Query: 858 LPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVE 917
P ++ SV LS L+P Y + + A E+ S P+ ++ T + +PR+L+ +
Sbjct: 679 EPASSTSVVLSSLKPETLYLVNVTAEYEDGFSIPLAGEETT-----EEVKGAPRNLKVTD 733
Query: 918 VTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKV 977
T I WT V YR+ PV GE + + L P Y V
Sbjct: 734 ETTDSFKITWTQAPGRVLRYRIIYRPV-AGGESREVTTPPNQRRRTLENLIPDTKYEVSV 792
Query: 978 FAVSHGRESKPLTAQQTTK--LDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTR 1035
PLT T+ P +L+ + T ST+ + W+ ++ Y +T
Sbjct: 793 IPEYFSGPGTPLTGNAATEEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTYTPVA 852
Query: 1036 RGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQP-GSSIPPY 1094
G+ ++ V + L+ L+ ++Y +S+ A+ + G TTL+ GS
Sbjct: 853 GGETQEVTVRGDTTNTVLQGLKEGTQYALSVTALYASGAGDALFGEGTTLEERGSPQDLV 912
Query: 1095 NTEVTETTIVITWTPAP------RIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVE 1148
++T+T+I WT AP R+ +K GE + + D+ ++ L P +
Sbjct: 913 TKDITDTSIGAYWTSAPGMVRGYRVSWKSLYDDVDTGE--KNLPEDAIHTMIENLQPETK 970
Query: 1149 YVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRI 1208
Y ++ E + P+ T LS + + V+W + + YR+
Sbjct: 971 YRISVFATYSSGEGE-PLTGDATTELSQDSKTLKVDEETENTMRVTW-KPAPGKVVNYRV 1028
Query: 1209 TTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESV--PISDTIIPE 1266
P +G + V +S L P Y+++V + E S T
Sbjct: 1029 VYRPHG--RGKQMVAKVPPTVTSTVLKRLQPQTTYDITVLPIYKMGEGKLRQGSGTTASR 1086
Query: 1267 VPQLTDLSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIFEDFVDSSVGYYTVT 1326
+L D T SS + W P + GY++T G+ + E V +
Sbjct: 1087 FKSPRNLKTSDPTMSSFRVTWEPA-PGEVKGYKVTFHPTGDDRRLGELVVGPYDNTVVLE 1145
Query: 1327 GLEPGIDYDISVITLINGGESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAP------ 1380
L G Y ++V + +GGES+P + T + T + + G + + A
Sbjct: 1146 ELRAGTTYKVNVFGMFDGGESSPLVGQEMTTLSDTTVMPILSSGMECLTRAEADIVLLVD 1205
Query: 1381 -PPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSV----SSVYEQ 1435
SI NF S + +V ++ A+ + P TE+ ++ S+ +
Sbjct: 1206 GSWSIGRANFRTVRSFISRIVEVFDIGPKRVQIALAQYSGDPRTEWQLNAHRDKKSLLQA 1265
Query: 1436 HESTPLRGRQKTGLDSPTGIDFSDITANSF-TVHWIAPRATITGYRIRHHPEHFSGRPRE 1494
+ P +G ++ TG+ + I +F T + PRA G I
Sbjct: 1266 VANLPYKGG-----NTLTGMALNFIRQQNFRTQAGMRPRARKIGVLITDGKSQDDVEAPS 1320
Query: 1495 DRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVS--------------- 1539
++ + + E + ++A + + + ++S
Sbjct: 1321 KKLKDEGVELFAIGIKNADEVELKMIATDPDDTHAYNVADFESLSRIVDDLTINLCNSVK 1380
Query: 1540 -----DVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTA 1594
+ P +L + T S +SW P+ +V Y++ Y G QEF V +++
Sbjct: 1381 GPGDLEAPSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSGGKR-QEFYVSRMETST 1439
Query: 1595 TISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWL 1654
+ LKP +Y + VY+V S+P+ +T + + DV ++ V+W
Sbjct: 1440 VLKDLKPETEYVVNVYSVV----EDEYSEPLKGTEKTLPVPVVSLNIYDVGPTTMHVQWQ 1495
Query: 1655 PSSSPVTGYRVTTTPKNGPGPTKTKTA--GPDQTEMTIEGLQPTVEYVVSVYAQNPSGES 1712
P TGY ++ P PT+ K GP +M + L P EY V+V A S
Sbjct: 1496 PVGG-ATGYILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTS 1554
Query: 1713 QPLVQTAVT-NIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAP 1771
+P+ VT + RP+ L DV ++ + WE G+V +Y V Y +PE+ + E+
Sbjct: 1555 EPVTVREVTLPLPRPQDLKLRDVTHSTMNVFWEPVPGKVRKYIVRYKTPEEDVKEV--EV 1612
Query: 1772 DGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQST-AIPAPTDLKFTQVTPTSLS 1830
D E + L+ L + YTVSV A+HD+ ES P+ ++T +PAPT+LK T+VT
Sbjct: 1613 DRSETSTSLKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPAPTNLKITEVTSEGFR 1672
Query: 1831 AQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYAL---- 1886
W ++ YR+ P + M+ I L D +++V L T YEVS+ A+
Sbjct: 1673 GTWDHGASDVSLYRITWAPFGSSDKMETI-LNGDENTLVFENLNPNTIYEVSITAIYPDE 1731
Query: 1887 ---KDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPAN 1943
D + S ++TT S PR +V +AT ++T+ W + + +++ P+
Sbjct: 1732 SESDDLIGSERTLPILTTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPST 1791
Query: 1944 GQTPIQ-RTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDAST-AIDAPSNLR 2001
G+ Q TI S + L+P T Y I + +L + + T ++ NLR
Sbjct: 1792 GEGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLR 1851
Query: 2002 FLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYT 2061
+ ++L V W Y + Y P E+VP P A + L+P T YT
Sbjct: 1852 VYDPSTSTLNVRWDHAEGNPRQYKLFYAPAAGGPEELVPIP-GNTNYAILRNLQPDTSYT 1910
Query: 2062 IYVI 2065
+ V+
Sbjct: 1911 VTVV 1914
Score = 261 bits (667), Expect = 6e-69
Identities = 250/933 (26%), Positives = 398/933 (42%), Gaps = 51/933 (5%)
Query: 728 VTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYI 787
++E T SF VSW SD+V ++VEY G + Q + TS + DL P +Y+
Sbjct: 1393 ISERTHRSFRVSWTPPSDSVDRYKVEY-YPVSGGKRQEFYVSRMETSTVLKDLKPETEYV 1451
Query: 788 VNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSP 847
VNVY + ED E S L ++ T P + V T++ V+W +P TGY + Y P
Sbjct: 1452 VNVYSVVED-EYSEPLKGTEKTLPVPVVSLNIYDVGPTTMHVQW-QPVGGATGYILSYKP 1509
Query: 848 SVEGSST---ELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRS 904
+ T E+ L T N + L+DL P +Y +T+ AV + S PV +++ T PR
Sbjct: 1510 VKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEPVTVREVTLPLPR- 1568
Query: 905 DTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRN-TFAE 963
P+DL+ +VT + + W P V Y ++ P E + + + R+ T
Sbjct: 1569 -----PQDLKLRDVTHSTMNVFWEPVPGKVRKY---IVRYKTPEEDVKEVEVDRSETSTS 1620
Query: 964 VTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTK-LDAPTNLQFVNETDSTVLVRWTPPRA 1022
+ L Y V AV ES P+TAQ+TT+ + APTNL+ T W +
Sbjct: 1621 LKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPAPTNLKITEVTSEGFRGTWDHGAS 1680
Query: 1023 QITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQE-------S 1075
++ YR+T + + + NL P + Y VS+ AI ++ S
Sbjct: 1681 DVSLYRITWAPFGSSDKMETILNGDENTLVFENLNPNTIYEVSITAIYPDESESDDLIGS 1740
Query: 1076 PKATGVFTTLQPGSSIPPYNTEV---TETTIVITWTPAP-RI-GFKLGVRPS--QGGEAP 1128
+ + TT P S P N +V T ++ + W PA R+ +++ +PS +G E
Sbjct: 1741 ERTLPILTTQAPKSG--PRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQT 1798
Query: 1129 REVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDT 1188
+ S+V+ L P Y T+ L E PL+ NL + +P T
Sbjct: 1799 TTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRV-YDPST 1857
Query: 1189 GVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVY 1248
L V W+ + + Y++ P G G + + + NL P Y V+V
Sbjct: 1858 STLNVRWDHA-EGNPRQYKLFYAPAAG--GPEELVPIPGNTNYAILRNLQPDTSYTVTVV 1914
Query: 1249 TVKDDKESVPISDTIIPEVPQLT-DLSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGE 1307
V + + SDT + L ++ + T +S+ +RW P ++ YR+
Sbjct: 1915 PVYTEGDGGRTSDTGRTLMRGLARNVQVYNPTPNSLDVRWDPA-PGPVLQYRVVYSPVDG 1973
Query: 1308 GIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAV-PPPTDLRF 1366
P V + + L P Y ++++ L + GE P+ +T P +LR
Sbjct: 1974 TRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGRTLPRSGPRNLRV 2033
Query: 1367 TNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYV 1426
+++ V W + + + YSP + ++ N V+L L P T Y
Sbjct: 2034 FGETTNSLSVAWDHADG-PVQQYRIIYSPTVGDPIDEYTTVPGRRNNVILQPLQPDTPYK 2092
Query: 1427 VSVSSVYEQHESTPLRGRQKT-GLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHP 1485
++V +VYE + L G +T GL P I SD F V W + + GY+I + P
Sbjct: 2093 ITVIAVYEDGDGGHLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPSPVLGYKIVYKP 2152
Query: 1486 EHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDL 1545
S P E V S TL NL P T Y V++ A S L Q +T+ DL
Sbjct: 2153 VG-SNEPMEAFV-GEMTSYTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQGTTLYLNVTDL 2210
Query: 1546 EVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDY 1605
+ + + W +P YR+ G QE TV GS+++ +GL P DY
Sbjct: 2211 KTYQIGWDTFCVKW-SPHRAATSYRLKLSPADGTRG-QEITVRGSETSHCFTGLSPDTDY 2268
Query: 1606 TITVYAVTGRGDSPASSKPISINYRTEIDKPSQ 1638
+TV+ T + P +S+ T + KP++
Sbjct: 2269 GVTVFVQTPNLEGPG----VSVKEHTTV-KPTE 2296
Score = 225 bits (573), Expect = 5e-58
Identities = 250/1005 (24%), Positives = 410/1005 (40%), Gaps = 90/1005 (8%)
Query: 1354 QQTAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNA 1413
++ A PP DL F+ + + W+P ++ ++ + Y +++V + + S +
Sbjct: 628 KKKAYVPPKDLSFSEVTSYGFKTNWSPAGE-NVFSYHITYKEAAGDDEVTVVEPA-SSTS 685
Query: 1414 VVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTG--LDSPTGIDFSDITANSFTVHWIA 1471
VVL++L P T Y+V+V++ YE S PL G + T +P + +D T +SF + W
Sbjct: 686 VVLSSLKPETLYLVNVTAEYEDGFSIPLAGEETTEEVKGAPRNLKVTDETTDSFKITWTQ 745
Query: 1472 PRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLL 1531
+ YRI + P G RE P ++ TL NL P T+Y VS++ L
Sbjct: 746 APGRVLRYRIIYRPVA-GGESREVTTPPNQRRRTLENLIPDTKYEVSVIPEYFSGPGTPL 804
Query: 1532 IGQQST--VSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPG 1589
G +T V PRDL V T +++ +SW V+ Y +TY G QE TV G
Sbjct: 805 TGNAATEEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTYTPVAGGE-TQEVTVRG 863
Query: 1590 SKSTATISGLKPGVDYTITVYAV--TGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDN 1647
+ + GLK G Y ++V A+ +G GD+ E P + D+ D
Sbjct: 864 DTTNTVLQGLKEGTQYALSVTALYASGAGDALFGEGTTL----EERGSPQDLVTKDITDT 919
Query: 1648 SISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQN 1707
SI W + V GYRV+ T K D IE LQP +Y +SV+A
Sbjct: 920 SIGAYWTSAPGMVRGYRVSWKSLYDDVDTGEKNLPEDAIHTMIENLQPETKYRISVFATY 979
Query: 1708 PSGESQPLVQTAVTNIDR-PKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHE 1766
SGE +PL A T + + K L + +++++ W+ G+V YRV Y G
Sbjct: 980 SSGEGEPLTGDATTELSQDSKTLKVDEETENTMRVTWKPAPGKVVNYRVVYRPHGRGKQM 1039
Query: 1767 LFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTA--IPAPTDLKFTQV 1824
+ P T L+ L+P + Y ++V+ ++ E + G+ +TA +P +LK +
Sbjct: 1040 VAKVPPTVTSTV-LKRLQPQTTYDITVLPIYKMGEGKLRQGSGTTASRFKSPRNLKTSDP 1098
Query: 1825 TPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVY 1884
T +S W P ++ GY+V P + E+ + P ++VV+ L T Y+V+V+
Sbjct: 1099 TMSSFRVTWEPAPGEVKGYKVTFHPTGDDRRLGELVVGPYDNTVVLEELRAGTTYKVNVF 1158
Query: 1885 ALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAV-PAN 1943
+ D S P G +T ++TT+ + E +T + D V +
Sbjct: 1159 GMFDGGESSPLVG-------------QEMTTLSDTTVMPILSSGMECLTRAEADIVLLVD 1205
Query: 1944 GQTPIQRTIKPDVRSYTITGLQPGTDY--KIYLYTLNDNARSSPVVIDASTAIDAPSNLR 2001
G I R VRS+ I+ + D K L + + D S L+
Sbjct: 1206 GSWSIGRANFRTVRSF-ISRIVEVFDIGPKRVQIALAQYSGDPRTEWQLNAHRDKKSLLQ 1264
Query: 2002 FLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYT 2061
+A P +TG + + + + + RPR IT + +
Sbjct: 1265 AVANLP-------YKGGNTLTGMALNFIRQQNFRTQAGMRPRARKIGVLITDGKSQDDVE 1317
Query: 2062 IYVIALKNNQKSEPLIGRKKTDELP-QLVTLPHPNLHGPEILDVPSTVQKTPFVTHPGYD 2120
LK+ IG K DE+ +++ + H + D S + +T +
Sbjct: 1318 APSKKLKDEGVELFAIGIKNADEVELKMIATDPDDTHAYNVADFESLSRIVDDLT---IN 1374
Query: 2121 TGNGIQLPGTSGQQPSVGQQMIFEE---HGFRRTTPPTTATPIRHRPRPYPPNVG--EEI 2175
N ++ PG + PS ++ E FR + P + + R++ YP + G +E
Sbjct: 1375 LCNSVKGPGDL-EAPS---NLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSGGKRQEF 1430
Query: 2176 QIGHIPREDVDYHLYPHGPGLNPNASTGQEALSQ-----------------------TT- 2211
+ + V L P + S ++ S+ TT
Sbjct: 1431 YVSRMETSTVLKDLKPETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVVSLNIYDVGPTTM 1490
Query: 2212 -ISWAPFQDTSEYIISCHPVGTDE--EPLQFRVPGTSTSATLTGLTRGATYNIIVEALKD 2268
+ W P + YI+S PV E P + R+ T LT L Y + V+A+
Sbjct: 1491 HVQWQPVGGATGYILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAV-- 1548
Query: 2269 QQRHKVREEVVTVGNSVNEGLNQPTDDSCFDPYTVSHYAVGDEWE 2313
H + E VTV V L +P D D V+H + WE
Sbjct: 1549 --LHDLTSEPVTV-REVTLPLPRPQDLKLRD---VTHSTMNVFWE 1587
Score = 201 bits (510), Expect = 1e-50
Identities = 214/835 (25%), Positives = 345/835 (41%), Gaps = 77/835 (9%)
Query: 623 PNSHPIQWNAPQP-SHISKYILRWRPKNSVG--RWKEATIPGHLNSYTIKGLKPGVVYEG 679
P + +QW QP + YIL ++P R KE + +N + L P Y
Sbjct: 1487 PTTMHVQW---QPVGGATGYILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYA- 1542
Query: 680 QLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSE-SVTEITASSFVV 738
+++Q H TS PVT VT PL + + ++T S+ V
Sbjct: 1543 --VTVQAVLHD----------LTSEPVTVREVT------LPLPRPQDLKLRDVTHSTMNV 1584
Query: 739 SWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGE 798
W V + V Y+ EE + +D T+TS+ DL Y V+V + ++GE
Sbjct: 1585 FWEPVPGKVRKYIVRYKTPEEDVKEVEVDRSETSTSLK--DLFSQTLYTVSVSAVHDEGE 1642
Query: 799 QSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNL 858
+ + T AP + + +V W + ++ YRI ++P E L
Sbjct: 1643 SPPVTAQETTRPVPAPTNLKITEVTSEGFRGTWDHGASDVSLYRITWAPFGSSDKMETIL 1702
Query: 859 PETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQE------TTGTPRSDTVPSPRD 912
N++ +L P Y ++I A+ ++ + +I E TT P+S PR+
Sbjct: 1703 NGDENTLVFENLNPNTIYEVSITAIYPDESESDDLIGSERTLPILTTQAPKS----GPRN 1758
Query: 913 LQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVT 972
LQ T +T+ W P V YR+ P G R + L P
Sbjct: 1759 LQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQTTTIGGRQNSVVLQKLKPDTP 1818
Query: 973 YYFKVFAVSHGRESKPLTAQQTTK-LDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTV 1031
Y V ++ E +T + TK L+ NL+ + + ST+ VRW Y+L
Sbjct: 1819 YTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRVYDPSTSTLNVRWDHAEGNPRQYKLFY 1878
Query: 1032 GLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPG--S 1089
G + + + LRNLQP + YTV++V + + + + TL G
Sbjct: 1879 APAAGGPEELVPIPGNTNYAILRNLQPDTSYTVTVVPVYTEGDGGRTSDTGRTLMRGLAR 1938
Query: 1090 SIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSG------- 1142
++ YN T ++ + W PAP + V S P + T S SIVV G
Sbjct: 1939 NVQVYNP--TPNSLDVRWDPAPGPVLQYRVVYS-----PVDGTRPSESIVVPGNTRMVHL 1991
Query: 1143 --LTPGVEY-VYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERST 1199
L P Y V + + DG+ +P + + P S P NL + T L+V+W+ +
Sbjct: 1992 ERLIPDTLYSVNLVALYSDGEGNPSPAQGRTL-PRSGPRNLRV-FGETTNSLSVAWDHAD 2049
Query: 1200 TPDITGYRITTTPTNGQQGNSLEE--VVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESV 1257
P + YRI +PT G+ ++E V +++ L P Y ++V V +D +
Sbjct: 2050 GP-VQQYRIIYSPT---VGDPIDEYTTVPGRRNNVILQPLQPDTPYKITVIAVYEDGDGG 2105
Query: 1258 PISD---TIIPEVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIFED 1314
++ T+ PQ +S D + + W P + S ++GY+I G P+ E
Sbjct: 2106 HLTGNGRTVGLLPPQNIHIS--DEWYTRFRVSWDP-SPSPVLGYKIVYKPVGSNEPM-EA 2161
Query: 1315 FVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAVPPPTDLRFTNIGPDTM 1374
FV YT+ L P YD++V + G S P T T TDL+ IG DT
Sbjct: 2162 FVGEMTS-YTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQGTTLYLNVTDLKTYQIGWDTF 2220
Query: 1375 RVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSV 1429
V W+P + T++ ++ SP E+++ S+ + T L P T+Y V+V
Sbjct: 2221 CVKWSPHRA--ATSYRLKLSPADGTRG-QEITVRGSETSHCFTGLSPDTDYGVTV 2272
Score = 173 bits (439), Expect = 2e-42
Identities = 183/796 (22%), Positives = 324/796 (40%), Gaps = 75/796 (9%)
Query: 1323 YTVTGLEPGIDYDISVITLINGG--ESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAP 1380
+ V + +D +I+ + G E ++ + V PP++L + +++ W P
Sbjct: 297 FNVANFDAIVDIQNEIISQVCSGVDEQLGELVSGEEVVEPPSNLIAMEVSSKYVKLNWNP 356
Query: 1381 PPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTP 1440
PS +T + V +P+ LS+ P + + +L TEY +SVS++ S P
Sbjct: 357 SPS-PVTGYKVILTPMTAGSRQHALSVGPQTTTLSVRDLSADTEYQISVSAMKGMTSSEP 415
Query: 1441 LRGRQKT-----------GLDSPTGIDFSDITANSFTV---HWIAPRA----TITGYRIR 1482
+ +KT G+D I F + S+++ +++ RA + + I
Sbjct: 416 ISIMEKTQPMKVQVECSRGVDIKADIVF--LVDGSYSIGIANFVKVRAFLEVLVKSFEIS 473
Query: 1483 HHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREES------------PL 1530
+ S + R PH+ TL T + + +I R S +
Sbjct: 474 PNRVQIS-LVQYSRDPHT--EFTLKKFTKVEDIIEAINTFPYRGGSTNTGKAMTYVREKI 530
Query: 1531 LIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTV--- 1587
+ + + S+VP+ + ++ +S ++ PA+ +R NS V+ F V
Sbjct: 531 FVPSKGSRSNVPKVMILITDGKSS--DAFRDPAIKLR-----------NSDVEIFAVGVK 577
Query: 1588 PGSKSTATISGLKPGVDYTITVYAVTG-RGDSPASSKPISINYRTEID--------KPSQ 1638
+S P + TV + S ++ I + E+ P
Sbjct: 578 DAVRSELEAIASPPAETHVFTVEDFDAFQRISFELTQSICLRIEQELAAIKKKAYVPPKD 637
Query: 1639 MQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGP-DQTEMTIEGLQPTV 1697
+ ++V W P+ V Y +T K G + P T + + L+P
Sbjct: 638 LSFSEVTSYGFKTNWSPAGENVFSYHITY--KEAAGDDEVTVVEPASSTSVVLSSLKPET 695
Query: 1698 EYVVSVYAQNPSGESQPLVQTAVTNIDR--PKGLAFTDVDVDSIKIAWESPQGQVSRYRV 1755
Y+V+V A+ G S PL T + P+ L TD DS KI W G+V RYR+
Sbjct: 696 LYLVNVTAEYEDGFSIPLAGEETTEEVKGAPRNLKVTDETTDSFKITWTQAPGRVLRYRI 755
Query: 1756 TYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQST--AI 1813
Y G P + L+ L P ++Y VSV+ + PL G +T
Sbjct: 756 IYRPVAGGESREVTTPPNQR-RRTLENLIPDTKYEVSVIPEYFSGPGTPLTGNAATEEVR 814
Query: 1814 PAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGL 1873
P DL+ + T +++ W+ ++ Y V TP G +E+ + D+++ V+ GL
Sbjct: 815 GNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTYTP-VAGGETQEVTVRGDTTNTVLQGL 873
Query: 1874 MVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETIT 1933
T+Y +SV AL + G TTLE P+ D T+T+I W + +
Sbjct: 874 KEGTQYALSVTALYASGAGDALFGEGTTLEERGSPQDLVTKDITDTSIGAYWTSAPGMVR 933
Query: 1934 GFQVDAVPANGQTPI-QRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDAST 1992
G++V ++ + D I LQP T Y+I ++ + P+ DA+T
Sbjct: 934 GYRVSWKSLYDDVDTGEKNLPEDAIHTMIENLQPETKYRISVFATYSSGEGEPLTGDATT 993
Query: 1993 AIDAPS-NLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATI 2051
+ S L+ T N++ V+W+P ++ Y + Y +P +++V + P VT +
Sbjct: 994 ELSQDSKTLKVDEETENTMRVTWKPAPGKVVNYRVVY-RPHGRGKQMVAKVPPTVTSTVL 1052
Query: 2052 TGLEPGTEYTIYVIAL 2067
L+P T Y I V+ +
Sbjct: 1053 KRLQPQTTYDITVLPI 1068
Score = 161 bits (407), Expect = 8e-39
Identities = 149/568 (26%), Positives = 249/568 (43%), Gaps = 27/568 (4%)
Query: 727 SVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKY 786
S +E+T+ F +W A + V + + Y+ + DE ++ P+++TSV + L P Y
Sbjct: 639 SFSEVTSYGFKTNWSPAGENVFSYHITYKEAAGDDEVTVVE-PASSTSVVLSSLKPETLY 697
Query: 787 IVNVYQISEDGEQSLILSTSQTT--APDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIV 844
+VNV EDG S+ L+ +TT AP + V S + W++ + YRI+
Sbjct: 698 LVNVTAEYEDGF-SIPLAGEETTEEVKGAPRNLKVTDETTDSFKITWTQAPGRVLRYRII 756
Query: 845 YSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRS 904
Y P G S E+ P TL +L P +Y +++ + TP+ TG +
Sbjct: 757 YRPVAGGESREVTTPPNQRRRTLENLIPDTKYEVSVIPEYFSGPGTPL------TGNAAT 810
Query: 905 DTV-PSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAE 963
+ V +PRDL+ + T + + W+ V Y V PV G Q + + +T
Sbjct: 811 EEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTYTPV--AGGETQEVTVRGDTTNT 868
Query: 964 V-TGLSPGVTYYFKVFAVSHGRESKPLTAQQTT--KLDAPTNLQFVNETDSTVLVRWTPP 1020
V GL G Y V A+ L + TT + +P +L + TD+++ WT
Sbjct: 869 VLQGLKEGTQYALSVTALYASGAGDALFGEGTTLEERGSPQDLVTKDITDTSIGAYWTSA 928
Query: 1021 RAQITGYRLT-VGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKAT 1079
+ GYR++ L + N+ + NLQP ++Y +S+ A + E T
Sbjct: 929 PGMVRGYRVSWKSLYDDVDTGEKNLPEDAIHTMIENLQPETKYRISVFATYSSGEGEPLT 988
Query: 1080 GVFTTLQPGSSIPPYNTEVTETTIVITWTPAPR--IGFKLGVRP-SQGGEAPREVTSDSG 1136
G TT S E TE T+ +TW PAP + +++ RP +G + +V
Sbjct: 989 GDATTELSQDSKTLKVDEETENTMRVTWKPAPGKVVNYRVVYRPHGRGKQMVAKVPPTVT 1048
Query: 1137 SIVVSGLTPGVEYVYTI-QVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSW 1195
S V+ L P Y T+ + + G+ + + P NL ++P V+W
Sbjct: 1049 STVLKRLQPQTTYDITVLPIYKMGEGKLRQGSGTTASRFKSPRNLK-TSDPTMSSFRVTW 1107
Query: 1196 ERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKE 1255
E ++ GY++T PT G E VV ++ + L G Y V+V+ + D E
Sbjct: 1108 E-PAPGEVKGYKVTFHPT-GDDRRLGELVVGPYDNTVVLEELRAGTTYKVNVFGMFDGGE 1165
Query: 1256 SVPISDTIIPEVPQLTDLSFVDITDSSI 1283
S P+ + E+ L+D + + I S +
Sbjct: 1166 SSPL---VGQEMTTLSDTTVMPILSSGM 1190
Score = 160 bits (405), Expect = 1e-38
Identities = 151/584 (25%), Positives = 255/584 (43%), Gaps = 28/584 (4%)
Query: 885 ENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPV 944
E +S + I+QE + VP P+DL F EVT W+P V Y +
Sbjct: 611 ELTQSICLRIEQELAAIKKKAYVP-PKDLSFSEVTSYGFKTNWSPAGENVFSYHITYKEA 669
Query: 945 NLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTK--LDAPTN 1002
E P S +T ++ L P Y V A S PL ++TT+ AP N
Sbjct: 670 AGDDEVTVVEPAS-STSVVLSSLKPETLYLVNVTAEYEDGFSIPLAGEETTEEVKGAPRN 728
Query: 1003 LQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEY 1062
L+ +ET + + WT ++ YR+ G+ R+ P+ + L NL P ++Y
Sbjct: 729 LKVTDETTDSFKITWTQAPGRVLRYRIIYRPVAGGESREVTTPPNQRRRTLENLIPDTKY 788
Query: 1063 TVSLVAIKGNQESPKATGVFTTLQ-PGSSIPPYNTEVTETTIVITWTPAPR--IGFKLGV 1119
VS++ + TG T + G+ ++ T +T+ ++W+ AP + +
Sbjct: 789 EVSVIPEYFSGPGTPLTGNAATEEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTY 848
Query: 1120 RPSQGGEAPREVT--SDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPI-VNKVVTPLSP 1176
P GGE +EVT D+ + V+ GL G +Y ++ L DA +
Sbjct: 849 TPVAGGET-QEVTVRGDTTNTVLQGLKEGTQYALSVTALYASGAGDALFGEGTTLEERGS 907
Query: 1177 PTNLHLEANPDTGVLTVSWERSTTPDITGYRIT----TTPTNGQQGNSLEEVVHADQSSC 1232
P +L + DT + ++ S + GYR++ + + N E+ +H
Sbjct: 908 PQDLVTKDITDTSI--GAYWTSAPGMVRGYRVSWKSLYDDVDTGEKNLPEDAIHT----- 960
Query: 1233 TFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPEVPQLTDLSFVD-ITDSSIGLRWTPLN 1291
+NL P +Y +SV+ E P++ E+ Q + VD T++++ + W P
Sbjct: 961 MIENLQPETKYRISVFATYSSGEGEPLTGDATTELSQDSKTLKVDEETENTMRVTWKPA- 1019
Query: 1292 SSTIIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTT 1351
++ YR+ G G + V +V + L+P YDI+V+ + GE
Sbjct: 1020 PGKVVNYRVVYRPHGRGKQMVAK-VPPTVTSTVLKRLQPQTTYDITVLPIYKMGEGKLRQ 1078
Query: 1352 LTQQTA--VPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISP 1409
+ TA P +L+ ++ + RVTW P P ++ + V + P ++ + EL + P
Sbjct: 1079 GSGTTASRFKSPRNLKTSDPTMSSFRVTWEPAPG-EVKGYKVTFHPTGDDRRLGELVVGP 1137
Query: 1410 SDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPT 1453
DN VVL L GT Y V+V +++ ES+PL G++ T L T
Sbjct: 1138 YDNTVVLEELRAGTTYKVNVFGMFDGGESSPLVGQEMTTLSDTT 1181
Score = 159 bits (403), Expect = 2e-38
Identities = 201/869 (23%), Positives = 340/869 (39%), Gaps = 73/869 (8%)
Query: 905 DTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPIS-RNTFAE 963
+ V P +L +EV+ V + W P S VTGY+V + P+ G L + + T
Sbjct: 332 EVVEPPSNLIAMEVSSKYVKLNWNPSPSPVTGYKVILTPMT-AGSRQHALSVGPQTTTLS 390
Query: 964 VTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTK-----------LDAPTNLQF-VNETDS 1011
V LS Y V A+ S+P++ + T+ +D ++ F V+ + S
Sbjct: 391 VRDLSADTEYQISVSAMKGMTSSEPISIMEKTQPMKVQVECSRGVDIKADIVFLVDGSYS 450
Query: 1012 TVLVRWTPPRA---------QITGYRLTVGL-----------TRRGQPRQYNVGPSVSKY 1051
+ + RA +I+ R+ + L T + + ++ +++ +
Sbjct: 451 IGIANFVKVRAFLEVLVKSFEISPNRVQISLVQYSRDPHTEFTLKKFTKVEDIIEAINTF 510
Query: 1052 PLR----NLQPASEYTVSLVAI--KGNQES-PKATGVFTTLQPGSSIPPYNTEVTETTIV 1104
P R N A Y + + KG++ + PK + T + + ++ + +
Sbjct: 511 PYRGGSTNTGKAMTYVREKIFVPSKGSRSNVPKVMILITDGKSSDAFRDPAIKLRNSDVE 570
Query: 1105 ITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDA 1164
I +G K VR A + ++ + + T + ++ A
Sbjct: 571 IF-----AVGVKDAVRSELEAIASPPAETHVFTVEDFDAFQRISFELTQSICLRIEQELA 625
Query: 1165 PIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEV 1224
I K P P +L G T +W ++ Y IT G + + V
Sbjct: 626 AIKKKAYVP---PKDLSFSEVTSYGFKT-NWS-PAGENVFSYHITYKEAAGD--DEVTVV 678
Query: 1225 VHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS--DTIIPEVPQLTDLSFVDITDSS 1282
A +S +L P Y V+V +D S+P++ +T +L D T S
Sbjct: 679 EPASSTSVVLSSLKPETLYLVNVTAEYEDGFSIPLAGEETTEEVKGAPRNLKVTDETTDS 738
Query: 1283 IGLRWTPLNSSTIIGYRITV--VAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVIT 1340
+ WT ++ YRI VA GE E + T+ L P Y++SVI
Sbjct: 739 FKITWTQA-PGRVLRYRIIYRPVAGGES---REVTTPPNQRRRTLENLIPDTKYEVSVIP 794
Query: 1341 LINGGESAPTT--LTQQTAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKN 1398
G P T + P DLR ++ TM+++W+ P + +LV Y+PV
Sbjct: 795 EYFSGPGTPLTGNAATEEVRGNPRDLRVSDPTTSTMKLSWSGAPG-KVKQYLVTYTPVAG 853
Query: 1399 EEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKT--GLDSPTGID 1456
E E+++ VL L GT+Y +SV+++Y L G T SP +
Sbjct: 854 GE-TQEVTVRGDTTNTVLQGLKEGTQYALSVTALYASGAGDALFGEGTTLEERGSPQDLV 912
Query: 1457 FSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYV 1516
DIT S +W + + GYR+ + E +P + NL P T+Y
Sbjct: 913 TKDITDTSIGAYWTSAPGMVRGYRVSWKSLYDDVDTGEKNLPEDAIHTMIENLQPETKYR 972
Query: 1517 VSIVALNGREESPLLIGQQST-VSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGE 1575
+S+ A E L G +T +S + L+V T ++ ++W V YR+ Y
Sbjct: 973 ISVFATYSSGEGEPLTGDATTELSQDSKTLKVDEETENTMRVTWKPAPGKVVNYRVVYRP 1032
Query: 1576 TG-GNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEID 1634
G G V + VP + ++ + L+P Y ITV + G+ + S +
Sbjct: 1033 HGRGKQMVAK--VPPTVTSTVLKRLQPQTTYDITVLPIYKMGE--GKLRQGSGTTASRFK 1088
Query: 1635 KPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQ 1694
P ++ +D +S V W P+ V GY+VT P GP + +E L+
Sbjct: 1089 SPRNLKTSDPTMSSFRVTWEPAPGEVKGYKVTFHPTGDDRRLGELVVGPYDNTVVLEELR 1148
Query: 1695 PTVEYVVSVYAQNPSGESQPLVQTAVTNI 1723
Y V+V+ GES PLV +T +
Sbjct: 1149 AGTTYKVNVFGMFDGGESSPLVGQEMTTL 1177
Score = 104 bits (259), Expect = 1e-21
Identities = 135/566 (23%), Positives = 212/566 (37%), Gaps = 91/566 (16%)
Query: 1803 QPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLA 1862
Q L + A P DL F++VT W+P + Y +T KE G + +
Sbjct: 622 QELAAIKKKAYVPPKDLSFSEVTSYGFKTNWSPAGENVFSY--HITYKEAAGDDEVTVVE 679
Query: 1863 PDSS-SVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTI 1921
P SS SVV+S L T Y V+V A + S P G TT E PR +VTD T +
Sbjct: 680 PASSTSVVLSSLKPETLYLVNVTAEYEDGFSIPLAGEETTEEVKGAPRNLKVTDETTDSF 739
Query: 1922 TISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNA 1981
I+W + +++ P G + T P+ R T+ L P T Y++ + +
Sbjct: 740 KITWTQAPGRVLRYRIIYRPVAGGESREVTTPPNQRRRTLENLIPDTKYEVSVIPEYFSG 799
Query: 1982 RSSPVVIDAST--AIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEK-PGSPPREV 2038
+P+ +A+T P +LR T +++ +SW ++ Y++ Y G +EV
Sbjct: 800 PGTPLTGNAATEEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTYTPVAGGETQEV 859
Query: 2039 VPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDE---LPQ-LVT---- 2090
R T + GL+ GT+Y + V AL + + L G T E PQ LVT
Sbjct: 860 T--VRGDTTNTVLQGLKEGTQYALSVTALYASGAGDALFGEGTTLEERGSPQDLVTKDIT 917
Query: 2091 -----------------------------------LPHPNLHGP-EILDVPSTVQKTPFV 2114
LP +H E L + + + F
Sbjct: 918 DTSIGAYWTSAPGMVRGYRVSWKSLYDDVDTGEKNLPEDAIHTMIENLQPETKYRISVFA 977
Query: 2115 THPGYDTGNGIQLPGTSGQQPSVGQQMI----FEEHGFRRTTPPTTATPIRHRP--RPY- 2167
T Y +G G L G + + S + + E+ R T P + +R RP+
Sbjct: 978 T---YSSGEGEPLTGDATTELSQDSKTLKVDEETENTMRVTWKPAPGKVVNYRVVYRPHG 1034
Query: 2168 ---------PPNVGEEIQIGHIPREDVDYHLYP----------HGPGLNP-------NAS 2201
PP V + P+ D + P G G N
Sbjct: 1035 RGKQMVAKVPPTVTSTVLKRLQPQTTYDITVLPIYKMGEGKLRQGSGTTASRFKSPRNLK 1094
Query: 2202 TGQEALSQTTISWAPFQ-DTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYN 2260
T +S ++W P + Y ++ HP G D + V + L L G TY
Sbjct: 1095 TSDPTMSSFRVTWEPAPGEVKGYKVTFHPTGDDRRLGELVVGPYDNTVVLEELRAGTTYK 1154
Query: 2261 IIVEALKD--QQRHKVREEVVTVGNS 2284
+ V + D + V +E+ T+ ++
Sbjct: 1155 VNVFGMFDGGESSPLVGQEMTTLSDT 1180
Score = 85.9 bits (211), Expect = 5e-16
Identities = 99/497 (19%), Positives = 183/497 (36%), Gaps = 61/497 (12%)
Query: 1633 IDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEG 1692
++ PS + +V + + W PS SPVTGY+V TP + GP T +++
Sbjct: 334 VEPPSNLIAMEVSSKYVKLNWNPSPSPVTGYKVILTPMTAGSRQHALSVGPQTTTLSVRD 393
Query: 1693 LQPTVEYVVSVYAQNPSGESQPL-----VQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQ 1747
L EY +SV A S+P+ Q ++ +G+ D+ D + + S
Sbjct: 394 LSADTEYQISVSAMKGMTSSEPISIMEKTQPMKVQVECSRGV---DIKADIVFLVDGSYS 450
Query: 1748 GQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDD----MESQ 1803
++ + + E + +P+ + + P +E+T+ +D + +
Sbjct: 451 IGIANFVKVRAFLEVLVKSFEISPNRVQISLVQYSRDPHTEFTLKKFTKVEDIIEAINTF 510
Query: 1804 PLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKE--INL 1861
P G + A T ++ P+ S P + +T + + ++ I L
Sbjct: 511 PYRGGSTNTGKAMTYVREKIFVPSKGSRSNVPK------VMILITDGKSSDAFRDPAIKL 564
Query: 1862 APDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVS--------------- 1906
+ G+ A + E+ + + S PA+ V T+E+
Sbjct: 565 RNSDVEIFAVGVKDAVRSEL------EAIASPPAETHVFTVEDFDAFQRISFELTQSICL 618
Query: 1907 ---------------PPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRT 1951
PP+ ++ T +W E + + + A G +
Sbjct: 619 RIEQELAAIKKKAYVPPKDLSFSEVTSYGFKTNWSPAGENVFSYHITYKEAAGDDEVTVV 678
Query: 1952 IKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDAST--AIDAPSNLRFLATTPNS 2009
S ++ L+P T Y + + ++ S P+ + +T AP NL+ T +S
Sbjct: 679 EPASSTSVVLSSLKPETLYLVNVTAEYEDGFSIPLAGEETTEEVKGAPRNLKVTDETTDS 738
Query: 2010 LLVSWQPPRARITGYIIKYEK-PGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALK 2068
++W R+ Y I Y G REV P T+ L P T+Y + VI
Sbjct: 739 FKITWTQAPGRVLRYRIIYRPVAGGESREVTTPPNQ--RRRTLENLIPDTKYEVSVIPEY 796
Query: 2069 NNQKSEPLIGRKKTDEL 2085
+ PL G T+E+
Sbjct: 797 FSGPGTPLTGNAATEEV 813
Score = 76.3 bits (186), Expect = 4e-13
Identities = 87/374 (23%), Positives = 149/374 (39%), Gaps = 54/374 (14%)
Query: 1904 NVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITG 1963
++ P +++ T + +SW ++++ ++V+ P +G + + S +
Sbjct: 1384 DLEAPSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSGGKRQEFYVSRMETSTVLKD 1443
Query: 1964 LQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITG 2023
L+P T+Y + +Y++ ++ S P+ T +L P ++ V WQP TG
Sbjct: 1444 LKPETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVVSLNIYDVGPTTMHVQWQPVGGA-TG 1502
Query: 2024 YIIKYE--KPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKK 2081
YI+ Y+ K P R R P V + +T L P TEY + V A+ ++ SEP+ R+
Sbjct: 1503 YILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEPVTVRE- 1561
Query: 2082 TDELPQLVTLPHPNLHGPEILDVPSTVQKTPFVTHPG--------YDT-GNGIQLPGTSG 2132
VTLP P ++ DV + + PG Y T ++
Sbjct: 1562 -------VTLPLPRPQDLKLRDVTHSTMNVFWEPVPGKVRKYIVRYKTPEEDVKEVEVDR 1614
Query: 2133 QQPSVGQQMIFEEHGF---------RRTTPPTTATPIRHRPRPYPPNVGEEIQIGHIPRE 2183
+ S + +F + + +PP TA RP P P N ++I + E
Sbjct: 1615 SETSTSLKDLFSQTLYTVSVSAVHDEGESPPVTAQETT-RPVPAPTN----LKITEVTSE 1669
Query: 2184 DVDYHLYPHGPGLNPNASTGQEALSQTTISWAPF--QDTSEYIISCHPVGTDEEPLQFR- 2240
G G +S I+WAPF D E I++ DE L F
Sbjct: 1670 -----------GFRGTWDHGASDVSLYRITWAPFGSSDKMETILN-----GDENTLVFEN 1713
Query: 2241 -VPGTSTSATLTGL 2253
P T ++T +
Sbjct: 1714 LNPNTIYEVSITAI 1727
Score = 66.6 bits (161), Expect = 3e-10
Identities = 37/123 (30%), Positives = 64/123 (52%), Gaps = 4/123 (3%)
Query: 800 SLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLP 859
+L+LS+ + D P D +D+ ++ + W++P PI GYRI P+ +G + E L
Sbjct: 15 ALLLSSIEAEV-DPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTTDGPTKEFTLS 73
Query: 860 ETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQ---QETTGTPRSDTVPSPRDLQFV 916
+ LS+L P +Y +TI + +E +ES PV+ Q Q + T + P ++Q
Sbjct: 74 ASTTETLLSELVPETEYVVTITSYDEVEESVPVIGQLTIQTGSSTKPVEKKPGKTEIQKC 133
Query: 917 EVT 919
V+
Sbjct: 134 SVS 136
Score = 65.9 bits (159), Expect = 5e-10
Identities = 75/320 (23%), Positives = 125/320 (39%), Gaps = 32/320 (10%)
Query: 595 GEWHCQPLQ--TYPSSSGP--VEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNS 650
GE + P Q T P S GP + VF T NS + W+ + +Y + + P
Sbjct: 2011 GEGNPSPAQGRTLPRS-GPRNLRVFGETT----NSLSVAWDHAD-GPVQQYRIIYSPTVG 2064
Query: 651 VGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNT 710
+ T+PG N+ ++ L+P Y+ +I++ + G
Sbjct: 2065 DPIDEYTTVPGRRNNVILQPLQPDTPYKITVIAVYEDGD------------------GGH 2106
Query: 711 VTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPS 770
+TG L + +++ + F VSW + V G+++ Y+ G
Sbjct: 2107 LTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPSPVLGYKIVYK--PVGSNEPMEAFVG 2164
Query: 771 TATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVR 830
TS + +L P Y VNVY + G S+ L+ TT D Q+ + V+
Sbjct: 2165 EMTSYTLHNLNPSTTYDVNVYAQYDSG-LSVPLTDQGTTLYLNVTDLKTYQIGWDTFCVK 2223
Query: 831 WSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQEST 890
WS P T YR+ SP+ E+ + + S + L P Y +T++ N E
Sbjct: 2224 WS-PHRAATSYRLKLSPADGTRGQEITVRGSETSHCFTGLSPDTDYGVTVFVQTPNLEGP 2282
Query: 891 PVVIQQETTGTPRSDTVPSP 910
V +++ TT P P
Sbjct: 2283 GVSVKEHTTVKPTEAPTEPP 2302
Score = 59.7 bits (143), Expect = 3e-08
Identities = 28/85 (32%), Positives = 44/85 (51%), Gaps = 1/85 (1%)
Query: 1632 EIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIE 1691
E+D PS + + +N++ + W P+ GYR+T P GPTK T TE +
Sbjct: 24 EVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTT-DGPTKEFTLSASTTETLLS 82
Query: 1692 GLQPTVEYVVSVYAQNPSGESQPLV 1716
L P EYVV++ + + ES P++
Sbjct: 83 ELVPETEYVVTITSYDEVEESVPVI 107
Score = 58.9 bits (141), Expect = 6e-08
Identities = 37/117 (31%), Positives = 59/117 (50%), Gaps = 5/117 (4%)
Query: 996 KLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRN 1055
++D P++L F ++TV + W P I GYR+TV T G +++ + S ++ L
Sbjct: 24 EVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTTDGPTKEFTLSASTTETLLSE 83
Query: 1056 LQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTI----VITWT 1108
L P +EY V++ + +ES G T+Q GSS P + +T I V WT
Sbjct: 84 LVPETEYVVTITSYDEVEESVPVIGQL-TIQTGSSTKPVEKKPGKTEIQKCSVSAWT 139
Score = 53.9 bits (128), Expect = 2e-06
Identities = 29/90 (32%), Positives = 49/90 (54%), Gaps = 2/90 (2%)
Query: 1355 QTAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAV 1414
+ V PP+DL F I +T+ ++WA P + + + P + E ++S S
Sbjct: 22 EAEVDPPSDLNFKIIDENTVHMSWAKPVD-PIVGYRITVDPT-TDGPTKEFTLSASTTET 79
Query: 1415 VLTNLLPGTEYVVSVSSVYEQHESTPLRGR 1444
+L+ L+P TEYVV+++S E ES P+ G+
Sbjct: 80 LLSELVPETEYVVTITSYDEVEESVPVIGQ 109
Score = 50.1 bits (118), Expect = 3e-05
Identities = 35/125 (28%), Positives = 58/125 (46%), Gaps = 7/125 (5%)
Query: 1715 LVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGE 1774
L+ + +D P L F +D +++ ++W P + YR+T DG + F
Sbjct: 17 LLSSIEAEVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTTDGPTKEFTLSAST 76
Query: 1775 EDTAELQGLRPGSEYTVSVVALHDDMESQPLIG-----TQSTAIPAPTDLKFTQVTPTSL 1829
+T L L P +EY V++ + + ES P+IG T S+ P T++ S+
Sbjct: 77 TETL-LSELVPETEYVVTITSYDEVEESVPVIGQLTIQTGSSTKPVEKKPGKTEIQKCSV 135
Query: 1830 SAQWT 1834
SA WT
Sbjct: 136 SA-WT 139
Score = 50.1 bits (118), Expect = 3e-05
Identities = 31/86 (36%), Positives = 44/86 (51%), Gaps = 1/86 (1%)
Query: 1449 LDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTN 1508
+D P+ ++F I N+ + W P I GYRI P G +E + S L+
Sbjct: 25 VDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTT-DGPTKEFTLSASTTETLLSE 83
Query: 1509 LTPGTEYVVSIVALNGREESPLLIGQ 1534
L P TEYVV+I + + EES +IGQ
Sbjct: 84 LVPETEYVVTITSYDEVEESVPVIGQ 109
Score = 48.9 bits (115), Expect = 6e-05
Identities = 26/96 (27%), Positives = 47/96 (48%), Gaps = 1/96 (1%)
Query: 1805 LIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPD 1864
L+ + + P+DL F + ++ W P + GYR+ V P GP KE L+
Sbjct: 17 LLSSIEAEVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDP-TTDGPTKEFTLSAS 75
Query: 1865 SSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVT 1900
++ ++S L+ T+Y V++ + + S P G +T
Sbjct: 76 TTETLLSELVPETEYVVTITSYDEVEESVPVIGQLT 111
Score = 45.1 bits (105), Expect = 9e-04
Identities = 28/96 (29%), Positives = 49/96 (51%), Gaps = 4/96 (4%)
Query: 1164 APIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEE 1223
A +++ + + PP++L+ + D + +SW + P I GYRIT PT G + E
Sbjct: 15 ALLLSSIEAEVDPPSDLNFKII-DENTVHMSWAKPVDP-IVGYRITVDPTT--DGPTKEF 70
Query: 1224 VVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPI 1259
+ A + L P EY V++ + + +ESVP+
Sbjct: 71 TLSASTTETLLSELVPETEYVVTITSYDEVEESVPV 106
Score = 45.1 bits (105), Expect = 9e-04
Identities = 23/110 (20%), Positives = 53/110 (48%), Gaps = 1/110 (0%)
Query: 790 VYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSV 849
+ Q+ ++ L S + P + +V + + W+ +P+TGY+++ +P
Sbjct: 313 ISQVCSGVDEQLGELVSGEEVVEPPSNLIAMEVSSKYVKLNWNPSPSPVTGYKVILTPMT 372
Query: 850 EGSSTE-LNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQET 898
GS L++ ++++ DL +Y I++ A++ S P+ I ++T
Sbjct: 373 AGSRQHALSVGPQTTTLSVRDLSADTEYQISVSAMKGMTSSEPISIMEKT 422
Score = 45.1 bits (105), Expect = 9e-04
Identities = 25/99 (25%), Positives = 45/99 (45%)
Query: 1987 VIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGV 2046
++ ++ PSNL + + + ++W P + +TGY + + R+ P
Sbjct: 327 LVSGEEVVEPPSNLIAMEVSSKYVKLNWNPSPSPVTGYKVILTPMTAGSRQHALSVGPQT 386
Query: 2047 TEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDEL 2085
T ++ L TEY I V A+K SEP+ +KT +
Sbjct: 387 TTLSVRDLSADTEYQISVSAMKGMTSSEPISIMEKTQPM 425
Score = 44.3 bits (103), Expect = 0.002
Identities = 36/131 (27%), Positives = 52/131 (39%), Gaps = 21/131 (16%)
Query: 1530 LLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPG 1589
LL+ D P DL ++ +SW P + YRIT T + P +EFT+
Sbjct: 16 LLLSSIEAEVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTT-DGPTKEFTLSA 74
Query: 1590 SKSTATISGLKPGVDYTITVYAV----------------TGRGDSPASSKPISINYRTEI 1633
S + +S L P +Y +T+ + TG P KP +TEI
Sbjct: 75 STTETLLSELVPETEYVVTITSYDEVEESVPVIGQLTIQTGSSTKPVEKKP----GKTEI 130
Query: 1634 DKPSQMQVTDV 1644
K S TD+
Sbjct: 131 QKCSVSAWTDL 141
Score = 42.7 bits (99), Expect = 0.004
Identities = 25/86 (29%), Positives = 41/86 (47%), Gaps = 1/86 (1%)
Query: 1994 IDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITG 2053
+D PS+L F N++ +SW P I GY I + P + TE ++
Sbjct: 25 VDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTTDGPTKEFTL-SASTTETLLSE 83
Query: 2054 LEPGTEYTIYVIALKNNQKSEPLIGR 2079
L P TEY + + + ++S P+IG+
Sbjct: 84 LVPETEYVVTITSYDEVEESVPVIGQ 109
Score = 36.2 bits (82), Expect = 0.41
Identities = 22/103 (21%), Positives = 45/103 (43%), Gaps = 1/103 (0%)
Query: 1886 LKDTLTSRPAQGVVTTLE-NVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANG 1944
L L + A +++++E V PP E T+ +SW + I G+++ P
Sbjct: 5 LPPALAALGAALLLSSIEAEVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTTD 64
Query: 1945 QTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVV 1987
+ T+ ++ L P T+Y + + + ++ S PV+
Sbjct: 65 GPTKEFTLSASTTETLLSELVPETEYVVTITSYDEVEESVPVI 107
Score = 35.0 bits (79), Expect = 0.92
Identities = 24/95 (25%), Positives = 38/95 (40%), Gaps = 1/95 (1%)
Query: 907 VPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTG 966
V P DL F + + V + W P + GYR+ V P G + + T ++
Sbjct: 25 VDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTT-DGPTKEFTLSASTTETLLSE 83
Query: 967 LSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPT 1001
L P Y + + ES P+ Q T + + T
Sbjct: 84 LVPETEYVVTITSYDEVEESVPVIGQLTIQTGSST 118
Score = 33.5 bits (75), Expect = 2.7
Identities = 18/79 (22%), Positives = 37/79 (46%), Gaps = 6/79 (7%)
Query: 738 VSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDG 797
+SW D + G+R+ + + +G ++ L ++ T + +L+P +Y+V + E
Sbjct: 43 MSWAKPVDPIVGYRITVDPTTDGPTKEF-TLSASTTETLLSELVPETEYVVTITSYDEVE 101
Query: 798 EQ-----SLILSTSQTTAP 811
E L + T +T P
Sbjct: 102 ESVPVIGQLTIQTGSSTKP 120
>gi|153946395 tenascin C precursor [Homo sapiens]
Length = 2201
Score = 380 bits (977), Expect = e-105
Identities = 314/1291 (24%), Positives = 542/1291 (41%), Gaps = 51/1291 (3%)
Query: 814 PPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGS-STELNLPETANSVTLSDLQP 872
P D V +V + ++ + W + +T Y +VY+P+ EG + +P S + +L+P
Sbjct: 626 PKDLVVTEVTEETVNLAWDN-EMRVTEYLVVYTPTHEGGLEMQFRVPGDQTSTIIQELEP 684
Query: 873 GVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPES 932
GV+Y I ++A+ EN++S PV + T +P+P L+F + + V + W P +
Sbjct: 685 GVEYFIRVFAILENKKSIPVSARVATY-------LPAPEGLKFKSIKETSVEVEWDPLDI 737
Query: 933 AVTGYRVDVIPVNLPGEHGQRLPISR-NTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTA 991
A + + +N E + R T TGL+PG Y + V + L
Sbjct: 738 AFETWEIIFRNMNKEDEGEITKSLRRPETSYRQTGLAPGQEYEISLHIVKNNTRGPGLKR 797
Query: 992 QQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTR-RGQPRQYNVGPSVSK 1050
TT+LDAP+ ++ + TD+T L+ W P A+I G LT G+ G ++ ++
Sbjct: 798 VTTTRLDAPSQIEVKDVTDTTALITWFKPLAEIDGIELTYGIKDVPGDRTTIDLTEDENQ 857
Query: 1051 YPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTET--TIVITWT 1108
Y + NL+P +EY VSL++ +G+ S A FTT G P V++T +I + W
Sbjct: 858 YSIGNLKPDTEYEVSLISRRGDMSSNPAKETFTT---GLDAPRNLRRVSQTDNSITLEWR 914
Query: 1109 --PAPRIGFKLGVRPSQGGE-----APREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQE 1161
A +++ P GG+ P+ + + + ++GL PG EY + +++ +E
Sbjct: 915 NGKAAIDSYRIKYAPISGGDHAEVDVPKSQQATTKT-TLTGLRPGTEYGIGVSAVKEDKE 973
Query: 1162 RDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRIT-TTPTNGQQGNS 1220
+ +N T L P +L + +T LT+ W ++ YR+ + PT G
Sbjct: 974 SNPATIN-AATELDTPKDLQVSETAETS-LTLLW-KTPLAKFDRYRLNYSLPTGQWVGVQ 1030
Query: 1221 LEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPE-VPQLTDLSFVDIT 1279
L + +S L PG EYNV + K +S P E P+L +L+ ++
Sbjct: 1031 LPR----NTTSYVLRGLEPGQEYNVLLTAEKGRHKSKPARVKASTEQAPELENLTVTEVG 1086
Query: 1280 DSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVI 1339
+ L WT + + + I V A + V S+ + GL+ Y +S+
Sbjct: 1087 WDGLRLNWTAADQA-YEHFIIQVQEANKVEAARNLTVPGSLRAVDIPGLKAATPYTVSIY 1145
Query: 1340 TLINGGESAPTTLTQQTAVPPPT-DLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKN 1398
+I G + + T P ++ +G D +++ W P F ++
Sbjct: 1146 GVIQGYRTPVLSAEASTGETPNLGEVVVAEVGWDALKLNWTAPEGA-YEYFFIQVQEADT 1204
Query: 1399 EEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTG-IDF 1457
E L++ + L L T Y +++ V + +TPL T G +
Sbjct: 1205 VEAAQNLTVPGGLRSTDLPGLKAATHYTITIRGVTQDFSTTPLSVEVLTEEVPDMGNLTV 1264
Query: 1458 SDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVV 1517
++++ ++ ++W P T + I+ VP S S+ + L GT Y V
Sbjct: 1265 TEVSWDALRLNWTTPDGTYDQFTIQVQEADQVEEAHNLTVPGSLRSMEIPGLRAGTPYTV 1324
Query: 1518 SIVA-LNGREESPLLIGQQSTVSDVPR--DLEVVAATPTSLLISWDAPAVTVRYYRITYG 1574
++ + G PL + + D+P+ DL V L ++W A ++ I
Sbjct: 1325 TLHGEVRGHSTRPLAV--EVVTEDLPQLGDLAVSEVGWDGLRLNWTAADNAYEHFVIQVQ 1382
Query: 1575 ETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEID 1634
E Q T+PGS I GL+ Y +++Y V +P S S EI
Sbjct: 1383 EVNKVEAAQNLTLPGSLRAVDIPGLEAATPYRVSIYGVIRGYRTPVLSAEASTAKEPEI- 1441
Query: 1635 KPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQ 1694
+ V+D+ S ++ W+ + + + N T + I GL
Sbjct: 1442 --GNLNVSDITPESFNLSWMATDGIFETFTIEIIDSNRLLETVEYNISGAERTAHISGLP 1499
Query: 1695 PTVEYVVSVYAQNPSGESQPLVQTAVTN-IDRPKGLAFTDVDVDSIKIAWESPQGQVSRY 1753
P+ +++V + PS ++ + TA T + + L +D++ ++W + + +
Sbjct: 1500 PSTDFIVYLSGLAPSIRTKTISATATTEALPLLENLTISDINPYGFTVSWMASENAFDSF 1559
Query: 1754 RVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQST-A 1812
VT + G + EL+GL G Y V V +++PL T A
Sbjct: 1560 LVTVVDSGKLLDPQEFTLSGTQRKLELRGLITGIGYEVMVSGFTQGHQTKPLRAEIVTEA 1619
Query: 1813 IPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSG 1872
P +L + TP WT + +++ +K EI L + ++G
Sbjct: 1620 EPEVDNLLVSDATPDGFRLSWTADEGVFDNFVLKIRDTKKQSEPLEITLLAPERTRDITG 1679
Query: 1873 LMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETI 1932
L AT+YE+ +Y + S+ + TT + P+ +D TE + T+SWR T +
Sbjct: 1680 LREATEYEIELYGISKGRRSQTVSAIATTA--MGSPKEVIFSDITENSATVSWRAPTAQV 1737
Query: 1933 TGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDAST 1992
F++ VP G TP T+ + L PG +Y + + + S PV +T
Sbjct: 1738 ESFRITYVPITGGTPSMVTVDGTKTQTRLVKLIPGVEYLVSIIAMKGFEESEPVSGSFTT 1797
Query: 1993 AIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATIT 2052
A+D PS L T + L WQP A + Y+I Y G E+ E +T
Sbjct: 1798 ALDGPSGLVTANITDSEALARWQPAIATVDSYVISY--TGEKVPEITRTVSGNTVEYALT 1855
Query: 2053 GLEPGTEYTIYVIALKNNQKSEPLIGRKKTD 2083
LEP TEYT+ + A K QKS + + TD
Sbjct: 1856 DLEPATEYTLRIFAEKGPQKSSTITAKFTTD 1886
Score = 366 bits (939), Expect = e-100
Identities = 337/1402 (24%), Positives = 598/1402 (42%), Gaps = 82/1402 (5%)
Query: 609 SGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTI 668
S P ++ +TE + + + W+ +++Y++ + P + G + +PG S I
Sbjct: 624 SPPKDLVVTEVTEETVN--LAWD--NEMRVTEYLVVYTPTHEGGLEMQFRVPGDQTSTII 679
Query: 669 KGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESV 728
+ L+PGV Y ++ +I + S PV++ T P
Sbjct: 680 QELEPGVEYFIRVFAILE-------------NKKSIPVSARVATYLPAP------EGLKF 720
Query: 729 TEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYL-DLPSTATSVNIPDLLPGRKYI 787
I +S V W + + + + DE + L TS L PG++Y
Sbjct: 721 KSIKETSVEVEWDPLDIAFETWEIIFRNMNKEDEGEITKSLRRPETSYRQTGLAPGQEYE 780
Query: 788 VNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYS- 846
++++ I ++ + L TT DAP V V DT+ ++ W +P A I G + Y
Sbjct: 781 ISLH-IVKNNTRGPGLKRVTTTRLDAPSQIEVKDVTDTTALITWFKPLAEIDGIELTYGI 839
Query: 847 PSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDT 906
V G T ++L E N ++ +L+P +Y +++ + + S P + TTG
Sbjct: 840 KDVPGDRTTIDLTEDENQYSIGNLKPDTEYEVSLISRRGDMSSNPAK-ETFTTG------ 892
Query: 907 VPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQ-RLPISRN--TFAE 963
+ +PR+L+ V TD +T+ W ++A+ YR+ P++ G+H + +P S+ T
Sbjct: 893 LDAPRNLRRVSQTDNSITLEWRNGKAAIDSYRIKYAPIS-GGDHAEVDVPKSQQATTKTT 951
Query: 964 VTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQ 1023
+TGL PG Y V AV +ES P T T+LD P +LQ ++++ + W P A+
Sbjct: 952 LTGLRPGTEYGIGVSAVKEDKESNPATINAATELDTPKDLQVSETAETSLTLLWKTPLAK 1011
Query: 1024 ITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFT 1083
YRL L GQ + + + Y LR L+P EY V L A KG +S A +
Sbjct: 1012 FDRYRLNYSLPT-GQWVGVQLPRNTTSYVLRGLEPGQEYNVLLTAEKGRHKSKPARVKAS 1070
Query: 1084 TLQPGSSIPPYNTEVTETTIVITWTPAPRI--GFKLGVRPSQGGEAPREVTSDSG--SIV 1139
T Q TEV + + WT A + F + V+ + EA R +T ++
Sbjct: 1071 TEQAPELENLTVTEVGWDGLRLNWTAADQAYEHFIIQVQEANKVEAARNLTVPGSLRAVD 1130
Query: 1140 VSGLTPGVEYVYTIQVLRDGQERDAPIVN-KVVTPLSPPTNLHLEANPDTGVLTVSWERS 1198
+ GL Y +I + G P+++ + T +P + A L ++W
Sbjct: 1131 IPGLKAATPYTVSIYGVIQGYR--TPVLSAEASTGETPNLGEVVVAEVGWDALKLNW--- 1185
Query: 1199 TTPDITGYRITTTPTNGQQGNSLEEV----VHADQSSCTFDNLSPGLEYNVSVYTVKDDK 1254
T P+ Y Q+ +++E V S L Y +++ V D
Sbjct: 1186 TAPE-GAYEYFFIQV--QEADTVEAAQNLTVPGGLRSTDLPGLKAATHYTITIRGVTQDF 1242
Query: 1255 ESVPIS-DTIIPEVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIFE 1313
+ P+S + + EVP + +L+ +++ ++ L WT + T + I V A +
Sbjct: 1243 STTPLSVEVLTEEVPDMGNLTVTEVSWDALRLNWTTPDG-TYDQFTIQVQEADQVEEAHN 1301
Query: 1314 DFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTA-VPPPTDLRFTNIGPD 1372
V S+ + GL G Y +++ + G + P + T +P DL + +G D
Sbjct: 1302 LTVPGSLRSMEIPGLRAGTPYTVTLHGEVRGHSTRPLAVEVVTEDLPQLGDLAVSEVGWD 1361
Query: 1373 TMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSV 1432
+R+ W + +F+++ V E L++ S AV + L T Y VS+ V
Sbjct: 1362 GLRLNWTAADNA-YEHFVIQVQEVNKVEAAQNLTLPGSLRAVDIPGLEAATPYRVSIYGV 1420
Query: 1433 YEQHESTPLRGRQKTGLDSPTG-IDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGR 1491
+ + L T + G ++ SDIT SF + W+A + I +
Sbjct: 1421 IRGYRTPVLSAEASTAKEPEIGNLNVSDITPESFNLSWMATDGIFETFTIEIIDSNRLLE 1480
Query: 1492 PREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVP--RDLEVVA 1549
E + + + ++ L P T+++V + L + I +T +P +L +
Sbjct: 1481 TVEYNISGAERTAHISGLPPSTDFIVYLSGLAPSIRTKT-ISATATTEALPLLENLTISD 1539
Query: 1550 ATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITV 1609
P +SW A + +T ++G QEFT+ G++ + GL G+ Y + V
Sbjct: 1540 INPYGFTVSWMASENAFDSFLVTVVDSGKLLDPQEFTLSGTQRKLELRGLITGIGYEVMV 1599
Query: 1610 YAVTGRGDSPASSKPISINYRTEID-KPSQMQVTDVQDNSISVKWLPSSSPVTGY--RVT 1666
T +KP+ TE + + + V+D + + W + ++
Sbjct: 1600 SGFT----QGHQTKPLRAEIVTEAEPEVDNLLVSDATPDGFRLSWTADEGVFDNFVLKIR 1655
Query: 1667 TTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRP 1726
T K P + P++T I GL+ EY + +Y + SQ + A T + P
Sbjct: 1656 DTKKQSE-PLEITLLAPERTR-DITGLREATEYEIELYGISKGRRSQTVSAIATTAMGSP 1713
Query: 1727 KGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPG 1786
K + F+D+ +S ++W +P QV +R+TY G + DG + L L PG
Sbjct: 1714 KEVIFSDITENSATVSWRAPTAQVESFRITYVPITGGTPSMVTV-DGTKTQTRLVKLIPG 1772
Query: 1787 SEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVR 1846
EY VS++A+ ES+P+ G+ +TA+ P+ L +T + A+W P + Y +
Sbjct: 1773 VEYLVSIIAMKGFEESEPVSGSFTTALDGPSGLVTANITDSEALARWQPAIATVDSYVIS 1832
Query: 1847 VTPKEKTGPMKEINLAPDSSSV--VVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLEN 1904
T ++ + EI ++V ++ L AT+Y + ++A K S TT +
Sbjct: 1833 YTGEK----VPEITRTVSGNTVEYALTDLEPATEYTLRIFAEKGPQKSSTITAKFTT--D 1886
Query: 1905 VSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGL 1964
+ PR T+ T ++WR ++TG+ + +G T + + PD SY++ L
Sbjct: 1887 LDSPRDLTATEVQSETALLTWRPPRASVTGYLLVYESVDG-TVKEVIVGPDTTSYSLADL 1945
Query: 1965 QPGTDYKIYLYTLNDNARSSPV 1986
P T Y + LN RS+ +
Sbjct: 1946 SPSTHYTAKIQALNGPLRSNMI 1967
Score = 337 bits (863), Expect = 1e-91
Identities = 324/1285 (25%), Positives = 539/1285 (41%), Gaps = 63/1285 (4%)
Query: 907 VPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTG 966
V P+DL EVT+ V + W E VT Y V P + G Q T +
Sbjct: 623 VSPPKDLVVTEVTEETVNLAW-DNEMRVTEYLVVYTPTHEGGLEMQFRVPGDQTSTIIQE 681
Query: 967 LSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITG 1026
L PGV Y+ +VFA+ ++S P++A+ T L AP L+F + +++V V W P
Sbjct: 682 LEPGVEYFIRVFAILENKKSIPVSARVATYLPAPEGLKFKSIKETSVEVEWDPLDIAFET 741
Query: 1027 YRL---TVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFT 1083
+ + + G+ + P S Y L P EY +SL +K N P V T
Sbjct: 742 WEIIFRNMNKEDEGEITKSLRRPETS-YRQTGLAPGQEYEISLHIVKNNTRGPGLKRVTT 800
Query: 1084 T-LQPGSSIPPYNTEVTETTIVITW-TPAPRI-GFKL--GVRPSQGGEAPREVTSDSGSI 1138
T L S I +VT+TT +ITW P I G +L G++ G ++T D
Sbjct: 801 TRLDAPSQIEV--KDVTDTTALITWFKPLAEIDGIELTYGIKDVPGDRTTIDLTEDENQY 858
Query: 1139 VVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERS 1198
+ L P EY ++ + R G P T L P NL + D + T+ W R+
Sbjct: 859 SIGNLKPDTEYEVSL-ISRRGDMSSNPAKETFTTGLDAPRNLRRVSQTDNSI-TLEW-RN 915
Query: 1199 TTPDITGYRITTTPTNGQQGNSLEEVVHADQ---SSCTFDNLSPGLEYNVSVYTVKDDKE 1255
I YRI P +G G+ E V Q + T L PG EY + V VK+DKE
Sbjct: 916 GKAAIDSYRIKYAPISG--GDHAEVDVPKSQQATTKTTLTGLRPGTEYGIGVSAVKEDKE 973
Query: 1256 SVPISDTIIPEVPQLTDLSFVDITDSSIGLRW-TPLNSSTIIGYRITV-VAAGEGIPIFE 1313
S P + E+ DL + ++S+ L W TPL + YR+ + G+ + +
Sbjct: 974 SNPATINAATELDTPKDLQVSETAETSLTLLWKTPL--AKFDRYRLNYSLPTGQWVGV-- 1029
Query: 1314 DFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAVPPPTD-LRFTNIGPD 1372
+ + Y + GLEPG +Y++ + +S P + T P + L T +G D
Sbjct: 1030 -QLPRNTTSYVLRGLEPGQEYNVLLTAEKGRHKSKPARVKASTEQAPELENLTVTEVGWD 1088
Query: 1373 TMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSV 1432
+R+ W +F+++ E L++ S AV + L T Y VS+ V
Sbjct: 1089 GLRLNWTAADQA-YEHFIIQVQEANKVEAARNLTVPGSLRAVDIPGLKAATPYTVSIYGV 1147
Query: 1433 YEQHESTPLRGRQKTGLDSPTG-IDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGR 1491
+ + + L TG G + +++ ++ ++W AP + I+
Sbjct: 1148 IQGYRTPVLSAEASTGETPNLGEVVVAEVGWDALKLNWTAPEGAYEYFFIQVQEADTVEA 1207
Query: 1492 PREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVP--RDLEVVA 1549
+ VP S L L T Y ++I + ++ S + + +VP +L V
Sbjct: 1208 AQNLTVPGGLRSTDLPGLKAATHYTITIRGVT-QDFSTTPLSVEVLTEEVPDMGNLTVTE 1266
Query: 1550 ATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITV 1609
+ +L ++W P T + I E TVPGS + I GL+ G YT+T+
Sbjct: 1267 VSWDALRLNWTTPDGTYDQFTIQVQEADQVEEAHNLTVPGSLRSMEIPGLRAGTPYTVTL 1326
Query: 1610 YAVTGRGDSPASSKPISINYRTE-IDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTT 1668
+ RG S++P+++ TE + + + V++V + + + W + + + +
Sbjct: 1327 HGEV-RGH---STRPLAVEVVTEDLPQLGDLAVSEVGWDGLRLNWTAADNAYEHFVIQVQ 1382
Query: 1669 PKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPK- 1727
N + T + I GL+ Y VS+Y G P++ + P+
Sbjct: 1383 EVNKVEAAQNLTLPGSLRAVDIPGLEAATPYRVSIYGV-IRGYRTPVLSAEASTAKEPEI 1441
Query: 1728 -GLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPG 1786
L +D+ +S ++W + G + + + + G E TA + GL P
Sbjct: 1442 GNLNVSDITPESFNLSWMATDGIFETFTIEIIDSNRLLETVEYNISGAERTAHISGLPPS 1501
Query: 1787 SEYTVSVVALHDDMESQPLIGTQST-AIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRV 1845
+++ V + L + ++ + T +T A+P +L + + P + W + V
Sbjct: 1502 TDFIVYLSGLAPSIRTKTISATATTEALPLLENLTISDINPYGFTVSWMASENAFDSFLV 1561
Query: 1846 RVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENV 1905
V K +E L+ + + GL+ YEV V ++P + + T E
Sbjct: 1562 TVVDSGKLLDPQEFTLSGTQRKLELRGLITGIGYEVMVSGFTQGHQTKPLRAEIVT-EAE 1620
Query: 1906 SPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQT-PIQRTIKPDVRSYTITGL 1964
V+DAT +SW F + Q+ P++ T+ R+ ITGL
Sbjct: 1621 PEVDNLLVSDATPDGFRLSWTADEGVFDNFVLKIRDTKKQSEPLEITLLAPERTRDITGL 1680
Query: 1965 QPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGY 2024
+ T+Y+I LY ++ RS V A+TA+ +P + F T NS VSW+ P A++ +
Sbjct: 1681 REATEYEIELYGISKGRRSQTVSAIATTAMGSPKEVIFSDITENSATVSWRAPTAQVESF 1740
Query: 2025 IIKYE--KPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKT 2082
I Y G+P V + T+ + L PG EY + +IA+K ++SEP+ G T
Sbjct: 1741 RITYVPITGGTPSMVTVDGTK---TQTRLVKLIPGVEYLVSIIAMKGFEESEPVSGSFTT 1797
Query: 2083 --DELPQLVTLPHPNLHG-----PEILDVPS-----TVQKTPFVTHPGYDTGNGIQLPGT 2130
D LVT + P I V S T +K P +T +GN ++ T
Sbjct: 1798 ALDGPSGLVTANITDSEALARWQPAIATVDSYVISYTGEKVPEITRT--VSGNTVEYALT 1855
Query: 2131 SGQQPSVGQQMIFEEHGFRRTTPPT 2155
+ + IF E G ++++ T
Sbjct: 1856 DLEPATEYTLRIFAEKGPQKSSTIT 1880
Score = 334 bits (856), Expect = 7e-91
Identities = 315/1382 (22%), Positives = 570/1382 (41%), Gaps = 84/1382 (6%)
Query: 728 VTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYI 787
VTE+T + ++W + V+ + V Y + EG +P TS I +L PG +Y
Sbjct: 631 VTEVTEETVNLAWDNEM-RVTEYLVVYTPTHEGGLEMQFRVPGDQTSTIIQELEPGVEYF 689
Query: 788 VNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVY-- 845
+ V+ I E+ ++S+ +S T AP + +TS+ V W + I++
Sbjct: 690 IRVFAILEN-KKSIPVSARVATYLPAPEGLKFKSIKETSVEVEWDPLDIAFETWEIIFRN 748
Query: 846 -SPSVEGSSTE-LNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPR 903
+ EG T+ L PET+ T L PG +Y I+++ V+ N + + T R
Sbjct: 749 MNKEDEGEITKSLRRPETSYRQT--GLAPGQEYEISLHIVKNNTRGPGL----KRVTTTR 802
Query: 904 SDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQ-RLPISRNTFA 962
D +P ++ +VTD I W P + + G + ++PG+ L N ++
Sbjct: 803 LD---APSQIEVKDVTDTTALITWFKPLAEIDGIELTYGIKDVPGDRTTIDLTEDENQYS 859
Query: 963 EVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRA 1022
+ L P Y + + S P TT LDAP NL+ V++TD+++ + W +A
Sbjct: 860 -IGNLKPDTEYEVSLISRRGDMSSNPAKETFTTGLDAPRNLRRVSQTDNSITLEWRNGKA 918
Query: 1023 QITGYRLTVGLTRRGQPRQYNVGPS---VSKYPLRNLQPASEYTVSLVAIKGNQESPKAT 1079
I YR+ G + +V S +K L L+P +EY + + A+K ++ES AT
Sbjct: 919 AIDSYRIKYAPISGGDHAEVDVPKSQQATTKTTLTGLRPGTEYGIGVSAVKEDKESNPAT 978
Query: 1080 -GVFTTLQPGSSIPPYNTEVTETTIVITW-TPAP-----RIGFKLGVRPSQGGEAPREVT 1132
T L + +E ET++ + W TP R+ + L G + PR T
Sbjct: 979 INAATELDTPKDLQV--SETAETSLTLLWKTPLAKFDRYRLNYSLPTGQWVGVQLPRNTT 1036
Query: 1133 SDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLT 1192
S V+ GL PG EY + G+ + P K T +P + V
Sbjct: 1037 S----YVLRGLEPGQEY-NVLLTAEKGRHKSKPARVKASTEQAPELE-------NLTVTE 1084
Query: 1193 VSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPG------------ 1240
V W+ G R+ T + + + +V A++ + PG
Sbjct: 1085 VGWD--------GLRLNWTAADQAYEHFIIQVQEANKVEAARNLTVPGSLRAVDIPGLKA 1136
Query: 1241 -LEYNVSVY-TVKDDKESVPISDTIIPEVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGY 1298
Y VS+Y ++ + V ++ E P L ++ ++ ++ L WT + Y
Sbjct: 1137 ATPYTVSIYGVIQGYRTPVLSAEASTGETPNLGEVVVAEVGWDALKLNWTAPEGA--YEY 1194
Query: 1299 RITVVAAGEGIPIFEDF-VDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTA 1357
V + + ++ V + + GL+ Y I++ + + P ++ T
Sbjct: 1195 FFIQVQEADTVEAAQNLTVPGGLRSTDLPGLKAATHYTITIRGVTQDFSTTPLSVEVLTE 1254
Query: 1358 -VPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVL 1416
VP +L T + D +R+ W P F ++ E+ L++ S ++ +
Sbjct: 1255 EVPDMGNLTVTEVSWDALRLNWTTPDGT-YDQFTIQVQEADQVEEAHNLTVPGSLRSMEI 1313
Query: 1417 TNLLPGTEYVVSVSSVYEQHESTPLRGRQKT-GLDSPTGIDFSDITANSFTVHWIAPRAT 1475
L GT Y V++ H + PL T L + S++ + ++W A
Sbjct: 1314 PGLRAGTPYTVTLHGEVRGHSTRPLAVEVVTEDLPQLGDLAVSEVGWDGLRLNWTAADNA 1373
Query: 1476 ITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQ 1535
+ I+ + + +P S ++ + L T Y VSI + +P+L +
Sbjct: 1374 YEHFVIQVQEVNKVEAAQNLTLPGSLRAVDIPGLEAATPYRVSIYGVIRGYRTPVLSAEA 1433
Query: 1536 STVSDVP-RDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTA 1594
ST + +L V TP S +SW A + I ++ E+ + G++ TA
Sbjct: 1434 STAKEPEIGNLNVSDITPESFNLSWMATDGIFETFTIEIIDSNRLLETVEYNISGAERTA 1493
Query: 1595 TISGLKPGVDYTITVYAVTGRGDSPA-SSKPISINYRTE-IDKPSQMQVTDVQDNSISVK 1652
ISGL P D+ + + G +P+ +K IS TE + + ++D+ +V
Sbjct: 1494 HISGLPPSTDFIVYL-----SGLAPSIRTKTISATATTEALPLLENLTISDINPYGFTVS 1548
Query: 1653 WLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGES 1712
W+ S + + VT + T Q ++ + GL + Y V V ++
Sbjct: 1549 WMASENAFDSFLVTVVDSGKLLDPQEFTLSGTQRKLELRGLITGIGYEVMVSGFTQGHQT 1608
Query: 1713 QPLVQTAVTNID-RPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAP 1771
+PL VT + L +D D +++W + +G + + + L
Sbjct: 1609 KPLRAEIVTEAEPEVDNLLVSDATPDGFRLSWTADEGVFDNFVLKIRDTKKQSEPLEITL 1668
Query: 1772 DGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSA 1831
E T ++ GLR +EY + + + SQ + +TA+ +P ++ F+ +T S +
Sbjct: 1669 LAPERTRDITGLREATEYEIELYGISKGRRSQTVSAIATTAMGSPKEVIFSDITENSATV 1728
Query: 1832 QWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLT 1891
W P Q+ +R+ P P + + + + L+ +Y VS+ A+K
Sbjct: 1729 SWRAPTAQVESFRITYVPITGGTPSM-VTVDGTKTQTRLVKLIPGVEYLVSIIAMKGFEE 1787
Query: 1892 SRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRT 1951
S P G TT + P + T++ W+ T+ + + + I RT
Sbjct: 1788 SEPVSGSFTTA--LDGPSGLVTANITDSEALARWQPAIATVDSYVI-SYTGEKVPEITRT 1844
Query: 1952 IKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLL 2011
+ + Y +T L+P T+Y + ++ +SS + +T +D+P +L + L
Sbjct: 1845 VSGNTVEYALTDLEPATEYTLRIFAEKGPQKSSTITAKFTTDLDSPRDLTATEVQSETAL 1904
Query: 2012 VSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQ 2071
++W+PPRA +TGY++ YE +EV+ P T ++ L P T YT + AL
Sbjct: 1905 LTWRPPRASVTGYLLVYESVDGTVKEVI--VGPDTTSYSLADLSPSTHYTAKIQALNGPL 1962
Query: 2072 KS 2073
+S
Sbjct: 1963 RS 1964
Score = 314 bits (805), Expect = 6e-85
Identities = 310/1276 (24%), Positives = 535/1276 (41%), Gaps = 96/1276 (7%)
Query: 665 SYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVAT 724
SY GL PG YE L ++ +T P T S +
Sbjct: 767 SYRQTGLAPGQEYEISLHIVKN--------------NTRGPGLKRVTTTRLDAPSQI--- 809
Query: 725 SESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGR 784
V ++T ++ +++W + G + Y + + + +DL +I +L P
Sbjct: 810 --EVKDVTDTTALITWFKPLAEIDGIELTYGIKDVPGDRTTIDLTEDENQYSIGNLKPDT 867
Query: 785 KYIVNVYQISEDGEQSLILSTSQ-TTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRI 843
+Y V++ IS G+ S + TT DAP + D SI + W +A I YRI
Sbjct: 868 EYEVSL--ISRRGDMSSNPAKETFTTGLDAPRNLRRVSQTDNSITLEWRNGKAAIDSYRI 925
Query: 844 VYSPSVEGSSTELNLPETANSVT---LSDLQPGVQYNITIYAVEENQESTPVVIQQETTG 900
Y+P G E+++P++ + T L+ L+PG +Y I + AV+E++ES P I T
Sbjct: 926 KYAPISGGDHAEVDVPKSQQATTKTTLTGLRPGTEYGIGVSAVKEDKESNPATINAATE- 984
Query: 901 TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT 960
+ +P+DLQ E + +T++W P + YR++ +LP + + RNT
Sbjct: 985 ------LDTPKDLQVSETAETSLTLLWKTPLAKFDRYRLNY---SLPTGQWVGVQLPRNT 1035
Query: 961 FAEVT-GLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPT--NLQFVNETDSTVLVRW 1017
+ V GL PG Y + A +SKP + +T+ AP NL + + W
Sbjct: 1036 TSYVLRGLEPGQEYNVLLTAEKGRHKSKPARVKASTE-QAPELENLTVTEVGWDGLRLNW 1094
Query: 1018 TPPRAQITGYRLTVGLTRRGQP-RQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESP 1076
T + + V + + R V S+ + L+ A+ YTVS+ + +P
Sbjct: 1095 TAADQAYEHFIIQVQEANKVEAARNLTVPGSLRAVDIPGLKAATPYTVSIYGVIQGYRTP 1154
Query: 1077 KATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFK---LGVRPSQGGEAPREVTS 1133
+ +T + + EV + + WT AP ++ + V+ + EA + +T
Sbjct: 1155 VLSAEASTGETPNLGEVVVAEVGWDALKLNWT-APEGAYEYFFIQVQEADTVEAAQNLTV 1213
Query: 1134 DSG--SIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVL 1191
G S + GL Y TI+ G +D TPLS + E PD G L
Sbjct: 1214 PGGLRSTDLPGLKAATHYTITIR----GVTQDFS-----TTPLS--VEVLTEEVPDMGNL 1262
Query: 1192 TV---SWERS----TTPDITGYRITTTPTNGQQGNSLEEV----VHADQSSCTFDNLSPG 1240
TV SW+ TTPD T + T Q+ + +EE V S L G
Sbjct: 1263 TVTEVSWDALRLNWTTPDGTYDQFTIQV---QEADQVEEAHNLTVPGSLRSMEIPGLRAG 1319
Query: 1241 LEYNVSVYTVKDDKESVPISDTIIPE-VPQLTDLSFVDITDSSIGLRWTPLNSS----TI 1295
Y V+++ + P++ ++ E +PQL DL+ ++ + L WT +++ I
Sbjct: 1320 TPYTVTLHGEVRGHSTRPLAVEVVTEDLPQLGDLAVSEVGWDGLRLNWTAADNAYEHFVI 1379
Query: 1296 IGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQ 1355
+ V A + + + S+ + GLE Y +S+ +I G + +
Sbjct: 1380 QVQEVNKVEAAQNLTL-----PGSLRAVDIPGLEAATPYRVSIYGVIRGYRTPVLSAEAS 1434
Query: 1356 TAVPPPT-DLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAV 1414
TA P +L ++I P++ ++W I T F + + E +IS ++
Sbjct: 1435 TAKEPEIGNLNVSDITPESFNLSWMATDGIFET-FTIEIIDSNRLLETVEYNISGAERTA 1493
Query: 1415 VLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKT-GLDSPTGIDFSDITANSFTVHWIAPR 1473
++ L P T+++V +S + + + T L + SDI FTV W+A
Sbjct: 1494 HISGLPPSTDFIVYLSGLAPSIRTKTISATATTEALPLLENLTISDINPYGFTVSWMASE 1553
Query: 1474 ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN-GREESPLLI 1532
+ + P+E + ++ + L L G Y V + G + PL
Sbjct: 1554 NAFDSFLVTVVDSGKLLDPQEFTLSGTQRKLELRGLITGIGYEVMVSGFTQGHQTKPLRA 1613
Query: 1533 GQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKS 1592
+ +L V ATP +SW A + + +T S E T+ +
Sbjct: 1614 EIVTEAEPEVDNLLVSDATPDGFRLSWTADEGVFDNFVLKIRDTKKQSEPLEITLLAPER 1673
Query: 1593 TATISGLKPGVDYTITVYAVT-GRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISV 1651
T I+GL+ +Y I +Y ++ GR S+ +S T + P ++ +D+ +NS +V
Sbjct: 1674 TRDITGLREATEYEIELYGISKGR-----RSQTVSAIATTAMGSPKEVIFSDITENSATV 1728
Query: 1652 KWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE 1711
W ++ V +R+T P G P+ G +T+ + L P VEY+VS+ A E
Sbjct: 1729 SWRAPTAQVESFRITYVPITGGTPSMVTVDGT-KTQTRLVKLIPGVEYLVSIIAMKGFEE 1787
Query: 1712 SQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAP 1771
S+P+ + T +D P GL ++ W+ V Y ++Y+ + + E+
Sbjct: 1788 SEPVSGSFTTALDGPSGLVTANITDSEALARWQPAIATVDSYVISYTGEK--VPEITRTV 1845
Query: 1772 DGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSA 1831
G L L P +EYT+ + A +S + +T + +P DL T+V +
Sbjct: 1846 SGNTVEYALTDLEPATEYTLRIFAEKGPQKSSTITAKFTTDLDSPRDLTATEVQSETALL 1905
Query: 1832 QWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLT 1891
W PP +TGY + + G +KE+ + PD++S ++ L +T Y + AL L
Sbjct: 1906 TWRPPRASVTGYLL--VYESVDGTVKEVIVGPDTTSYSLADLSPSTHYTAKIQALNGPLR 1963
Query: 1892 SRPAQGVVTTLENVSP 1907
S Q + TT+ + P
Sbjct: 1964 SNMIQTIFTTIGLLYP 1979
Score = 221 bits (564), Expect = 5e-57
Identities = 247/1093 (22%), Positives = 427/1093 (39%), Gaps = 117/1093 (10%)
Query: 1266 EVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIFEDFVDSSVGYYTV 1325
EV DL ++T+ ++ L W N + Y + EG + V +
Sbjct: 622 EVSPPKDLVVTEVTEETVNLAWD--NEMRVTEYLVVYTPTHEGGLEMQFRVPGDQTSTII 679
Query: 1326 TGLEPGIDYDISVITLINGGESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAPPPSID 1385
LEPG++Y I V ++ +S P + T +P P L+F +I ++ V W P
Sbjct: 680 QELEPGVEYFIRVFAILENKKSIPVSARVATYLPAPEGLKFKSIKETSVEVEWDPLDIAF 739
Query: 1386 LTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQ 1445
T ++ + K +E S+ + + T L PG EY +S+ V L+
Sbjct: 740 ETWEIIFRNMNKEDEGEITKSLRRPETSYRQTGLAPGQEYEISLHIVKNNTRGPGLKRVT 799
Query: 1446 KTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSIT 1505
T LD+P+ I+ D+T + + W P A I G + + + G + N +
Sbjct: 800 TTRLDAPSQIEVKDVTDTTALITWFKPLAEIDGIELTYGIKDVPGDRTTIDLTEDENQYS 859
Query: 1506 LTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVT 1565
+ NL P TEY VS+++ G S +T D PR+L V+ T S+ + W
Sbjct: 860 IGNLKPDTEYEVSLISRRGDMSSNPAKETFTTGLDAPRNLRRVSQTDNSITLEWRNGKAA 919
Query: 1566 VRYYRITYGETGGNSPVQEFTVPGSK---STATISGLKPGVDYTITVYAVTGRGDSPASS 1622
+ YRI Y G E VP S+ + T++GL+PG +Y I V AV S
Sbjct: 920 IDSYRIKYAPISGGDHA-EVDVPKSQQATTKTTLTGLRPGTEYGIGVSAV----KEDKES 974
Query: 1623 KPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPG-----PTK 1677
P +IN TE+D P +QV++ + S+++ W + YR+ + G P
Sbjct: 975 NPATINAATELDTPKDLQVSETAETSLTLLWKTPLAKFDRYRLNYSLPTGQWVGVQLPRN 1034
Query: 1678 TKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPL-VQTAVTNIDRPKGLAFTDVDV 1736
T T + GL+P EY V + A+ +S+P V+ + + L T+V
Sbjct: 1035 T-------TSYVLRGLEPGQEYNVLLTAEKGRHKSKPARVKASTEQAPELENLTVTEVGW 1087
Query: 1737 DSIKIAWESPQGQVSRY--RVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVV 1794
D +++ W + + +V ++ + L G ++ GL+ + YTVS+
Sbjct: 1088 DGLRLNWTAADQAYEHFIIQVQEANKVEAARNL--TVPGSLRAVDIPGLKAATPYTVSIY 1145
Query: 1795 ALHDDMESQPLIGTQSTA-IPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKT 1853
+ + L ST P ++ +V +L WT P + ++V +
Sbjct: 1146 GVIQGYRTPVLSAEASTGETPNLGEVVVAEVGWDALKLNWTAPEGAYEYFFIQVQEADTV 1205
Query: 1854 GPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARV 1913
+ + + S + GL AT Y +++ + ++ P V T E V V
Sbjct: 1206 EAAQNLTVPGGLRSTDLPGLKAATHYTITIRGVTQDFSTTPLSVEVLT-EEVPDMGNLTV 1264
Query: 1914 TDATETTITISWRTKTETITGFQVDAVPANG-QTPIQRTIKPDVRSYTITGLQPGTDYKI 1972
T+ + + ++W T T F + A+ + T+ +RS I GL+ GT Y +
Sbjct: 1265 TEVSWDALRLNWTTPDGTYDQFTIQVQEADQVEEAHNLTVPGSLRSMEIPGLRAGTPYTV 1324
Query: 1973 YLYTLNDNARSSPVVIDASTAIDAP--SNLRFLATTPNSLLVSWQPPRARITGYIIKYEK 2030
L+ + P+ ++ T D P +L + L ++W ++I+ ++
Sbjct: 1325 TLHGEVRGHSTRPLAVEVVTE-DLPQLGDLAVSEVGWDGLRLNWTAADNAYEHFVIQVQE 1383
Query: 2031 PGSPPREVVPRPRPGVTEAT-ITGLEPGTEY--TIY---------VIALKNNQKSEPLIG 2078
+ PG A I GLE T Y +IY V++ + + EP IG
Sbjct: 1384 V-NKVEAAQNLTLPGSLRAVDIPGLEAATPYRVSIYGVIRGYRTPVLSAEASTAKEPEIG 1442
Query: 2079 RKKTDEL-PQLVTLPHPNLHG------PEILDVPSTVQKTPFVTHPGYDTGNGIQLPGT- 2130
++ P+ L G EI+D ++ + T + LP +
Sbjct: 1443 NLNVSDITPESFNLSWMATDGIFETFTIEIIDSNRLLETVEYNISGAERTAHISGLPPST 1502
Query: 2131 ------SGQQPSVGQQMIFEEHGFRRTTPPTTATPIRHRPRPYPPNVGEEIQIGHIPRED 2184
SG PS+ + I T T A P+ E + I I
Sbjct: 1503 DFIVYLSGLAPSIRTKTI-------SATATTEALPLL-----------ENLTISDI---- 1540
Query: 2185 VDYHLYPHGPGLNPNASTGQEALSQTTISWAPFQDT-SEYIISCHPVGTDEEPLQFRVPG 2243
NP T +SW ++ ++++ G +P +F + G
Sbjct: 1541 ------------NPYGFT---------VSWMASENAFDSFLVTVVDSGKLLDPQEFTLSG 1579
Query: 2244 TSTSATLTGLTRGATYNIIVEAL-KDQQRHKVREEVVT----------VGNSVNEG--LN 2290
T L GL G Y ++V + Q +R E+VT V ++ +G L+
Sbjct: 1580 TQRKLELRGLITGIGYEVMVSGFTQGHQTKPLRAEIVTEAEPEVDNLLVSDATPDGFRLS 1639
Query: 2291 QPTDDSCFDPYTV 2303
D+ FD + +
Sbjct: 1640 WTADEGVFDNFVL 1652
Score = 213 bits (541), Expect = 2e-54
Identities = 156/656 (23%), Positives = 288/656 (43%), Gaps = 17/656 (2%)
Query: 1443 GRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRN 1502
G + + P + +++T + + W +T Y + + P H G + RVP +
Sbjct: 617 GEDCSEVSPPKDLVVTEVTEETVNLAW-DNEMRVTEYLVVYTPTHEGGLEMQFRVPGDQT 675
Query: 1503 SITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAP 1562
S + L PG EY + + A+ ++S + + +T P L+ + TS+ + WD
Sbjct: 676 STIIQELEPGVEYFIRVFAILENKKSIPVSARVATYLPAPEGLKFKSIKETSVEVEWDPL 735
Query: 1563 AVTVRYYRITYGETGGNSPVQ-EFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPAS 1621
+ + I + + ++ +++ +GL PG +Y I+++ V P
Sbjct: 736 DIAFETWEIIFRNMNKEDEGEITKSLRRPETSYRQTGLAPGQEYEISLHIVKNNTRGPGL 795
Query: 1622 SKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTA 1681
+ + T +D PSQ++V DV D + + W + + G +T K+ PG T
Sbjct: 796 KRVTT----TRLDAPSQIEVKDVTDTTALITWFKPLAEIDGIELTYGIKDVPGDRTTIDL 851
Query: 1682 GPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKI 1741
D+ + +I L+P EY VS+ ++ S P +T T +D P+ L +SI +
Sbjct: 852 TEDENQYSIGNLKPDTEYEVSLISRRGDMSSNPAKETFTTGLDAPRNLRRVSQTDNSITL 911
Query: 1742 AWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAE--LQGLRPGSEYTVSVVALHDD 1799
W + + + YR+ Y+ G H P ++ T + L GLRPG+EY + V A+ +D
Sbjct: 912 EWRNGKAAIDSYRIKYAPISGGDHAEVDVPKSQQATTKTTLTGLRPGTEYGIGVSAVKED 971
Query: 1800 MESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEI 1859
ES P +T + P DL+ ++ TSL+ W P + YR+ + TG +
Sbjct: 972 KESNPATINAATELDTPKDLQVSETAETSLTLLWKTPLAKFDRYRLNYS--LPTGQWVGV 1029
Query: 1860 NLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATET 1919
L +++S V+ GL +Y V + A K S+PA+ V + E VT+
Sbjct: 1030 QLPRNTTSYVLRGLEPGQEYNVLLTAEKGRHKSKPAR-VKASTEQAPELENLTVTEVGWD 1088
Query: 1920 TITISWRTKTETITGFQVDAVPANG-QTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLN 1978
+ ++W + F + AN + T+ +R+ I GL+ T Y + +Y +
Sbjct: 1089 GLRLNWTAADQAYEHFIIQVQEANKVEAARNLTVPGSLRAVDIPGLKAATPYTVSIYGVI 1148
Query: 1979 DNARSSPVVIDASTAIDAPSNLRFLATTP---NSLLVSWQPPRARITGYIIKYEKPGSPP 2035
R+ + +AST + P NL + ++L ++W P + I+ ++ +
Sbjct: 1149 QGYRTPVLSAEASTG-ETP-NLGEVVVAEVGWDALKLNWTAPEGAYEYFFIQVQEADTVE 1206
Query: 2036 REVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELPQLVTL 2091
G+ + GL+ T YTI + + + + PL T+E+P + L
Sbjct: 1207 AAQNLTVPGGLRSTDLPGLKAATHYTITIRGVTQDFSTTPLSVEVLTEEVPDMGNL 1262
Score = 152 bits (385), Expect = 3e-36
Identities = 152/694 (21%), Positives = 275/694 (39%), Gaps = 47/694 (6%)
Query: 628 IQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQY 687
+ W A ++ ++++ + N V + T+PG L + I GL+ Y + + +
Sbjct: 1365 LNWTAADNAY-EHFVIQVQEVNKVEAAQNLTLPGSLRAVDIPGLEAATPYRVSIYGVIR- 1422
Query: 688 GHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTV 747
G++ TPV S + P + +V++IT SF +SW++
Sbjct: 1423 GYR-------------TPVLSAEASTAKEP----EIGNLNVSDITPESFNLSWMATDGIF 1465
Query: 748 SGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQ 807
F +E S E ++ + +I L P +IV + ++ I +T+
Sbjct: 1466 ETFTIEIIDSNRLLETVEYNISGAERTAHISGLPPSTDFIVYLSGLAPSIRTKTISATAT 1525
Query: 808 TTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEG-SSTELNLPETANSVT 866
T A + T+ ++ V W + + + S + E L T +
Sbjct: 1526 TEALPLLENLTISDINPYGFTVSWMASENAFDSFLVTVVDSGKLLDPQEFTLSGTQRKLE 1585
Query: 867 LSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIM 926
L L G+ Y + + + ++ P+ + T P D +L + T +
Sbjct: 1586 LRGLITGIGYEVMVSGFTQGHQTKPLRAEIVTEAEPEVD------NLLVSDATPDGFRLS 1639
Query: 927 WTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRES 986
WT E + + + E + ++ ++TGL Y +++ +S GR S
Sbjct: 1640 WTADEGVFDNFVLKIRDTKKQSEPLEITLLAPERTRDITGLREATEYEIELYGISKGRRS 1699
Query: 987 KPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGP 1046
+ ++A TT + +P + F + T+++ V W P AQ+ +R+T G P V
Sbjct: 1700 QTVSAIATTAMGSPKEVIFSDITENSATVSWRAPTAQVESFRITYVPITGGTPSMVTVDG 1759
Query: 1047 SVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVIT 1106
+ ++ L L P EY VS++A+KG +ES +G FTT G S +T++ +
Sbjct: 1760 TKTQTRLVKLIPGVEYLVSIIAMKGFEESEPVSGSFTTALDGPS-GLVTANITDSEALAR 1818
Query: 1107 WTPAPRI--GFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDA 1164
W PA + + + E R V+ ++ ++ L P EY I G ++ +
Sbjct: 1819 WQPAIATVDSYVISYTGEKVPEITRTVSGNTVEYALTDLEPATEYTLRI-FAEKGPQKSS 1877
Query: 1165 PIVNKVVTPLSPPTNL-HLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEE 1223
I K T L P +L E +T +LT W R +TGY + + G E
Sbjct: 1878 TITAKFTTDLDSPRDLTATEVQSETALLT--W-RPPRASVTGYLLVYESVD---GTVKEV 1931
Query: 1224 VVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPEVPQLTDLSFVDITDSSI 1283
+V D +S + +LSP Y + + P+ +I + L + D S
Sbjct: 1932 IVGPDTTSYSLADLSPSTHYTAKIQALNG-----PLRSNMIQTIFTTIGLLYPFPKDCSQ 1986
Query: 1284 GLRWTPLNSSTIIGYRITVVAAGEGIPIFEDFVD 1317
+ LN T G T+ G+ E F D
Sbjct: 1987 AM----LNGDTTSGL-YTIYLNGDKAEALEVFCD 2015
>gi|188528648 tenascin XB isoform 1 precursor [Homo sapiens]
Length = 4242
Score = 338 bits (867), Expect = 4e-92
Identities = 430/1924 (22%), Positives = 730/1924 (37%), Gaps = 329/1924 (17%)
Query: 616 ITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGV 675
+T T S P+S + W PQ S S + ++++ ++ GR + + G + T+ GL+PG
Sbjct: 1378 LTVTGSSPDSLSLFWTVPQGSFDS-FTVQYKDRD--GRPRAVRVGGKESEVTVGGLEPGH 1434
Query: 676 VYEGQLISIQQYGHQEVTRFD-FTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITAS 734
Y+ L YG E R + + P T +P P + +VT++T +
Sbjct: 1435 KYKMHL-----YGLHEGQRVGPVSAVGVTAPQQEETPPATESPLEPRLGEL-TVTDVTPN 1488
Query: 735 SFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQIS 794
S +SW F V+Y+ ++ +PQ + + + V + +L P RKY +N+Y +
Sbjct: 1489 SVGLSWTVPEGQFDSFIVQYK--DKDGQPQVVPVAADQREVTVYNLEPERKYKMNMYGL- 1545
Query: 795 EDGEQSLILSTSQTTAPDAPPDP----------------TVDQVDDTSIVVRWSRPQAPI 838
DG++ LS TAP PP P TV + S+ + W+ P+
Sbjct: 1546 HDGQRMGPLSVVIVTAP-LPPAPATEASKPPLEPRLGELTVTDITPDSVGLSWTVPEGEF 1604
Query: 839 TGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQET 898
+ + Y +G + + VT+ DL+P +Y ++ +++ + +PV ++ +T
Sbjct: 1605 DSFVVQYKDR-DGQPQVVPVAADQREVTIPDLEPSRKYKFLLFGIQDGKRRSPVSVEAKT 1663
Query: 899 TGTPRSDTVPSPR--DLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPI 956
+ PR +L + T + + WT PE + V + P Q +P+
Sbjct: 1664 VARGDASPGAPPRLGELWVTDPTPDSLRLSWTVPEGQFDSFVVQFKDKDGP----QVVPV 1719
Query: 957 S-RNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTN------------- 1002
VT L G Y F ++ + + PLTA TT+ + +
Sbjct: 1720 EGHERSVTVTPLDAGRKYRFLLYGLLGKKRHGPLTADGTTEARSAMDDTGTKRPPKPRLG 1779
Query: 1003 --LQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPAS 1060
LQ T ++V + WT P Q + + R GQP+ V S+ + + L PA
Sbjct: 1780 EELQVTTVTQNSVGLSWTVPEGQFDSFVVQYK-DRDGQPQVVPVEGSLREVSVPGLDPAH 1838
Query: 1061 EYT--------------VSLVAIK-GNQESPKATGVFTTLQPGSSIPPYNTE-VTETTIV 1104
Y +S VAI G +E+ T T P + E T T+
Sbjct: 1839 RYKLLLYGLHHGKRVGPISAVAITAGREETETETTAPTPPAPEPHLGELTVEEATSHTLH 1898
Query: 1105 ITW--TPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQER 1162
++W T F++ G + D I +SGL Y+ T+ DG+
Sbjct: 1899 LSWMVTEGEFDSFEIQYTDRDGQLQMVRIGGDRNDITLSGLESDHRYLVTLYGFSDGKHV 1958
Query: 1163 -----DAPIVNKVVTPLSPPTNL-HLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQ 1216
+A V + P PPT P G LTV+ TPD ++ T GQ
Sbjct: 1959 GPVHVEALTVPEEEKPSEPPTATPEPPIKPRLGELTVT---DATPD--SLSLSWTVPEGQ 2013
Query: 1217 QGNSLEEVVHAD-----------QSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS----- 1260
+ L + + D + T L P +Y +++Y + P+S
Sbjct: 2014 FDHFLVQYRNGDGQPKAVRVPGHEEGVTISGLEPDHKYKMNLYGFHGGQRMGPVSVVGVT 2073
Query: 1261 ----DTIIP-----------EVPQLTDLSFVDITDSSIGLRWTPLNS---STIIGYRITV 1302
+T P E P L +L+ + S+ L WT S + Y+
Sbjct: 2074 AAEEETPSPTEPSMEAPEPAEEPLLGELTVTGSSPDSLSLSWTVPQGRFDSFTVQYKDR- 2132
Query: 1303 VAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAVP--- 1359
+G P V TV GLEPG Y + + L G P + TA
Sbjct: 2133 ----DGRPQVVR-VGGEESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVSAVGVTAPEEES 2187
Query: 1360 ---PPTDLRF-----TNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSD 1411
P LR +I D++ ++W P +FLV++ + + + +
Sbjct: 2188 PDAPLAKLRLGQMTVRDITSDSLSLSWTVPEG-QFDHFLVQFK--NGDGQPKAVRVPGHE 2244
Query: 1412 NAVVLTNLLPGTEYVVSVSSVYEQHESTPLR--GRQKTGLDS---------PTG------ 1454
+ V ++ L P +Y +++ + P+ G G D PT
Sbjct: 2245 DGVTISGLEPDHKYKMNLYGFHGGQRVGPVSAVGLTAPGKDEEMAPASTEPPTPEPPIKP 2304
Query: 1455 ----IDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLT 1510
+ +D T +S ++ W P + +++ ++ G+P+ RVP + +T++ L
Sbjct: 2305 RLEELTVTDATPDSLSLSWTVPEGQFDHFLVQY--KNGDGQPKATRVPGHEDRVTISGLE 2362
Query: 1511 PGTEYVVSIVALNG---------------REESPLLIGQQSTVSDVPRD-----LEVVAA 1550
P +Y +++ +G EE+P + P + L V +
Sbjct: 2363 PDNKYKMNLYGFHGGQRVGPVSAIGVTAAEEETPSPTEPSMEAPEPPEEPLLGELTVTGS 2422
Query: 1551 TPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVY 1610
+P SL +SW P + + Y + G V V G +S T+ GL+PG Y + +Y
Sbjct: 2423 SPDSLSLSWTVPQGRFDSFTVQYKDRDGRPQVVR--VGGEESEVTVGGLEPGRKYKMHLY 2480
Query: 1611 AV-TGRGDSPASSKPISINYRTEIDKPS------------------QMQVTDVQDNSISV 1651
+ GR P S+ ++ + PS ++ VT +S+S+
Sbjct: 2481 GLHEGRRVGPVSTVGVTAPQEDVDETPSPTEPGTEAPGPPEEPLLGELTVTGSSPDSLSL 2540
Query: 1652 KWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE 1711
W + T K+ G + G ++++T+ GL+P +Y + +Y +
Sbjct: 2541 SWTVPQGRFDSF--TVQYKDRDGRPQAVRVGGQESKVTVRGLEPGRKYKMHLYGLHEGRR 2598
Query: 1712 SQPLVQTAVTNID------------------RPKGLAFTDVDVDSIKIAWESPQGQVSRY 1753
P+ VT + R L TD DS+ ++W P+GQ +
Sbjct: 2599 LGPVSAVGVTEDEAETTQAVPTMTPEPPIKPRLGELTMTDATPDSLSLSWTVPEGQFDHF 2658
Query: 1754 RVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAI 1813
V Y + DG + P G ED + GL P +Y +++ H P+ TA
Sbjct: 2659 LVQYRNG-DGQPKAVRVP-GHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPISVIGVTAA 2716
Query: 1814 ----PAPTDLK----------------FTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKT 1853
P+PT+L T +P SLS WT P + V+ K++
Sbjct: 2717 EEETPSPTELSTEAPEPPEEPLLGELTVTGSSPDSLSLSWTIPQGHFDSFTVQY--KDRD 2774
Query: 1854 GPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVS------- 1906
G + + + + S V V GL KY++ +Y L + P V T +
Sbjct: 2775 GRPQVMRVRGEESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVSTVGVTEDEAETTQAVPT 2834
Query: 1907 ----PPRRAR-----VTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVR 1957
PP + R VTDAT ++++SW F V +GQ + R +
Sbjct: 2835 TTPEPPNKPRLGELTVTDATPDSLSLSWMVPEGQFDHFLVQYRNGDGQPKVVR-VPGHED 2893
Query: 1958 SYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAID----APSN-------------- 1999
TI+GL+P YK+ LY + R P+ + TA + AP+
Sbjct: 2894 GVTISGLEPDHKYKMNLYGFHGGQRVGPISVIGVTAAEEETPAPTEPSTEAPEPPEEPLL 2953
Query: 2000 --LRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPG 2057
L ++P+SL +SW P+ R + ++Y+ P+ V R R +E T+ GLEPG
Sbjct: 2954 GELTVTGSSPDSLSLSWTIPQGRFDSFTVQYKDRDGRPQVV--RVRGEESEVTVGGLEPG 3011
Query: 2058 TEYTIYVIALKNNQKSEPLIG---------RKKTDELPQLVTLP--HPNLHGPEILDVPS 2106
+Y +++ L Q+ P+ + T +P + P P L + D
Sbjct: 3012 CKYKMHLYGLHEGQRVGPVSAVGVTAPKDEAETTQAVPTMTPEPPIKPRLGELTVTDATP 3071
Query: 2107 TVQKTPFVTHPG--------YDTGNG----IQLPG------TSGQQPSVGQQM-IFEEHG 2147
++ G Y G+G +++PG SG +P +M ++ HG
Sbjct: 3072 DSLSLSWMVPEGQFDHFLVQYRNGDGQPKAVRVPGHEDGVTISGLEPDHKYKMNLYGFHG 3131
Query: 2148 FRRTTPPTTATPIRHRPRPYPPNVGEEIQIGHIPREDVDYHLYPHGPGLNPNASTGQEAL 2207
+R P +A + P P E P P L TG
Sbjct: 3132 GQR-VGPVSAIGVTEEETPSPTEPSTEAPEA------------PEEPLLGELTVTGSSP- 3177
Query: 2208 SQTTISWAPFQDTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALK 2267
++SW Q + + D +P RV G + T+ GL G Y + + L
Sbjct: 3178 DSLSLSWTVPQGRFD-SFTVQYKDRDGQPQVVRVRGEESEVTVGGLEPGRKYKMHLYGLH 3236
Query: 2268 DQQR 2271
+ QR
Sbjct: 3237 EGQR 3240
Score = 307 bits (787), Expect = 7e-83
Identities = 362/1637 (22%), Positives = 630/1637 (38%), Gaps = 236/1637 (14%)
Query: 616 ITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGV 675
+T T S P+S + W PQ + ++++ ++ GR + + G + T+ GL+PG
Sbjct: 2417 LTVTGSSPDSLSLSWTVPQ-GRFDSFTVQYKDRD--GRPQVVRVGGEESEVTVGGLEPGR 2473
Query: 676 VYEGQLISIQQYGHQEVTRFD-FTTTSTSTPVTSNTVTGETT---------PFSPLVATS 725
Y+ L YG E R +T + P T T P PL+
Sbjct: 2474 KYKMHL-----YGLHEGRRVGPVSTVGVTAPQEDVDETPSPTEPGTEAPGPPEEPLLGEL 2528
Query: 726 ESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRK 785
+VT + S +SW F V+Y+ + PQ + + + V + L PGRK
Sbjct: 2529 -TVTGSSPDSLSLSWTVPQGRFDSFTVQYK--DRDGRPQAVRVGGQESKVTVRGLEPGRK 2585
Query: 786 YIVNVYQISED---GEQSLILSTSQ---------TTAPDAPPDPTVDQVDDT-----SIV 828
Y +++Y + E G S + T T P+ P P + ++ T S+
Sbjct: 2586 YKMHLYGLHEGRRLGPVSAVGVTEDEAETTQAVPTMTPEPPIKPRLGELTMTDATPDSLS 2645
Query: 829 VRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQE 888
+ W+ P+ + + Y +G + +P + VT+S L+P +Y + +Y Q
Sbjct: 2646 LSWTVPEGQFDHFLVQYRNG-DGQPKAVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQR 2704
Query: 889 STPVVI-----QQETTGTPRSDTVPSPRDLQFVEVTDVKVT--------IMWTPPESAVT 935
P+ + +E T +P + +P + + ++ VT + WT P+
Sbjct: 2705 VGPISVIGVTAAEEETPSPTELSTEAPEPPEEPLLGELTVTGSSPDSLSLSWTIPQG--- 2761
Query: 936 GYRVDVIPVNLPGEHGQ-RLPISRNTFAEVT--GLSPGVTYYFKVFAVSHGRESKPLTAQ 992
D V G+ ++ R +EVT GL PG Y ++ + GR P++
Sbjct: 2762 --HFDSFTVQYKDRDGRPQVMRVRGEESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVSTV 2819
Query: 993 QTTKLDAPTN------------------LQFVNETDSTVLVRWTPPRAQITGYRLTVGLT 1034
T+ +A T L + T ++ + W P Q + L
Sbjct: 2820 GVTEDEAETTQAVPTTTPEPPNKPRLGELTVTDATPDSLSLSWMVPEGQFDHF-LVQYRN 2878
Query: 1035 RRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTL--------- 1085
GQP+ V + L+P +Y ++L G Q + + T
Sbjct: 2879 GDGQPKVVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPISVIGVTAAEEETPAPT 2938
Query: 1086 QPGSSIP-----PYNTEVTET-----TIVITWT-PAPRI-GFKLGVRPSQGGEAPREVTS 1133
+P + P P E+T T ++ ++WT P R F + + G V
Sbjct: 2939 EPSTEAPEPPEEPLLGELTVTGSSPDSLSLSWTIPQGRFDSFTVQYKDRDGRPQVVRVRG 2998
Query: 1134 DSGSIVVSGLTPGVEYVYTIQVLRDGQERD--------APIVNKVVTPLSPPTNLHLEAN 1185
+ + V GL PG +Y + L +GQ AP T P
Sbjct: 2999 EESEVTVGGLEPGCKYKMHLYGLHEGQRVGPVSAVGVTAPKDEAETTQAVPTMTPEPPIK 3058
Query: 1186 PDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHAD-----------QSSCTF 1234
P G LTV+ TPD ++ GQ + L + + D + T
Sbjct: 3059 PRLGELTVT---DATPD--SLSLSWMVPEGQFDHFLVQYRNGDGQPKAVRVPGHEDGVTI 3113
Query: 1235 DNLSPGLEYNVSVYTVKDDKESVPISDTII------------------PEVPQLTDLSFV 1276
L P +Y +++Y + P+S + PE P L +L+
Sbjct: 3114 SGLEPDHKYKMNLYGFHGGQRVGPVSAIGVTEEETPSPTEPSTEAPEAPEEPLLGELTVT 3173
Query: 1277 DITDSSIGLRWTP----LNSSTII-----GYRITVVAAGEGIPIFEDFVDSSVGYYTVTG 1327
+ S+ L WT +S T+ G V GE +S V TV G
Sbjct: 3174 GSSPDSLSLSWTVPQGRFDSFTVQYKDRDGQPQVVRVRGE---------ESEV---TVGG 3221
Query: 1328 LEPGIDYDISVITLINGGESAPTTLTQQTAVPPPT---------DLRFTNIGPDTMRVTW 1378
LEPG Y + + L G P + TA P PT +L + D++ ++W
Sbjct: 3222 LEPGRKYKMHLYGLHEGQRVGPVSTVGITA-PLPTPLPVEPRLGELAVAAVTSDSVGLSW 3280
Query: 1379 APPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHES 1438
+FLV+Y + + + +S AV ++ L P +Y + +
Sbjct: 3281 TVAQG-PFDSFLVQYRDAQGQPQA--VPVSGDLRAVAVSGLDPARKYKFLLFGLQNGKRH 3337
Query: 1439 TPLRGRQKTGLDSPTG-----IDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPR 1493
P+ +T D+ + +D T +S + W P + +++ + GR +
Sbjct: 3338 GPVPVEARTAPDTKPSPRLGELTVTDATPDSVGLSWTVPEGEFDSFVVQYKDK--DGRLQ 3395
Query: 1494 EDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTV---SDVPR---DLEV 1547
V ++ +T+ L P +Y + L+GR+ + +T ++P +L V
Sbjct: 3396 VVPVAANQREVTVQGLEPSRKYRFLLYGLSGRKRLGPISADSTTAPLEKELPPHLGELTV 3455
Query: 1548 VAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTI 1607
T +SL +SW + + Y +T G + V + T T+ L+PG Y
Sbjct: 3456 AEETSSSLRLSWTVAQGPFDSFVVQYRDTDGQP--RAVPVAADQRTVTVEDLEPGKKYKF 3513
Query: 1608 TVYAVTG---------------RGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVK 1652
+Y + G D+PA E + + VTD +S+ +
Sbjct: 3514 LLYGLLGGKRLGPVSALGMTAPEEDTPAPELAPEAPEPPEEPRLGVLTVTDTTPDSMRLS 3573
Query: 1653 WLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGES 1712
W + P + V NG P G DQ+++ I GL+P+ Y +Y +
Sbjct: 3574 WSVAQGPFDSFVVQYEDTNGQ-PQALLVDG-DQSKILISGLEPSTPYRFLLYGLHEGKRL 3631
Query: 1713 QPLVQTAVTNI---------DRPK--GLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPE 1761
PL T + RP+ L+ TDV S+++ WE+P G + + + P
Sbjct: 3632 GPLSAEGTTGLAPAGQTSEESRPRLSQLSVTDVTTSSLRLNWEAPPGAFDSFLLRFGVPS 3691
Query: 1762 DGIHELFPAP--------DGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAI 1813
E P P G +A L+ LR G+ Y++++ L ++ + GT T
Sbjct: 3692 PSTLEPHPRPLLQRELMVPGTRHSAVLRDLRSGTLYSLTLYGLRGPHKADSIQGTARTLS 3751
Query: 1814 P---APTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVV 1870
P +P DL+F+++ TS W PP + ++V + P + + + + + +
Sbjct: 3752 PVLESPRDLQFSEIRETSAKVNWMPPPSRADSFKVSYQLADGGEP-QSVQVDGQARTQKL 3810
Query: 1871 SGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTE 1930
GL+ +YEV+V +++ S P G +TT+ + P + R + TE + W+
Sbjct: 3811 QGLIPGARYEVTVVSVRGFEESEPLTGFLTTVPD--GPTQLRALNLTEGFAVLHWKPPQN 3868
Query: 1931 TITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDA 1990
+ + V V A G P+Q Y + L T+Y + L +SP I
Sbjct: 3869 PVDTYDVQ-VTAPGAPPLQAETPGSAVDYPLHDLVLHTNYTATVRGLRGPNLTSPASITF 3927
Query: 1991 STAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEAT 2050
+T ++AP +L TP + L++W P R GY++ + PG +E++ G+T
Sbjct: 3928 TTGLEAPRDLEAKEVTPRTALLTWTEPPVRPAGYLLSFHTPGGQNQEIL--LPGGITSHQ 3985
Query: 2051 ITGLEPGTEYTIYVIAL 2067
+ GL P T Y + A+
Sbjct: 3986 LLGLFPSTSYNARLQAM 4002
Score = 304 bits (779), Expect = 6e-82
Identities = 385/1785 (21%), Positives = 665/1785 (37%), Gaps = 280/1785 (15%)
Query: 616 ITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGV 675
+T T + P+S + W P+ +++++ KN G+ K +PGH + TI GL+P
Sbjct: 2309 LTVTDATPDSLSLSWTVPE-GQFDHFLVQY--KNGDGQPKATRVPGHEDRVTISGLEPDN 2365
Query: 676 VYEGQLISIQQYGHQEV---TRFDFTTTSTSTPV-TSNTVTGETTPFSPLVATSESVTEI 731
Y+ L +G Q V + T TP T ++ P PL+ +VT
Sbjct: 2366 KYKMNLYGF--HGGQRVGPVSAIGVTAAEEETPSPTEPSMEAPEPPEEPLLGEL-TVTGS 2422
Query: 732 TASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVY 791
+ S +SW F V+Y+ + PQ + + + V + L PGRKY +++Y
Sbjct: 2423 SPDSLSLSWTVPQGRFDSFTVQYK--DRDGRPQVVRVGGEESEVTVGGLEPGRKYKMHLY 2480
Query: 792 QI-----------------SEDGEQSLILSTSQTTAPDAPPDPTVDQVDDT-----SIVV 829
+ ED +++ + T AP P +P + ++ T S+ +
Sbjct: 2481 GLHEGRRVGPVSTVGVTAPQEDVDETPSPTEPGTEAPGPPEEPLLGELTVTGSSPDSLSL 2540
Query: 830 RWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQES 889
W+ PQ + + Y +G + + + VT+ L+PG +Y + +Y + E +
Sbjct: 2541 SWTVPQGRFDSFTVQYKDR-DGRPQAVRVGGQESKVTVRGLEPGRKYKMHLYGLHEGRRL 2599
Query: 890 TPV-----------VIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYR 938
PV Q T TP P +L + T +++ WT PE +
Sbjct: 2600 GPVSAVGVTEDEAETTQAVPTMTPEPPIKPRLGELTMTDATPDSLSLSWTVPEG-----Q 2654
Query: 939 VDVIPVNLPGEHGQ----RLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQT 994
D V GQ R+P ++GL P Y ++ G+ P++
Sbjct: 2655 FDHFLVQYRNGDGQPKAVRVP-GHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPISVIGV 2713
Query: 995 TKLDAPT--------------------NLQFVNETDSTVLVRWTPPRAQITGYRLTVGLT 1034
T + T L + ++ + WT P+ + +
Sbjct: 2714 TAAEEETPSPTELSTEAPEPPEEPLLGELTVTGSSPDSLSLSWTIPQGHFDSFTVQYK-D 2772
Query: 1035 RRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAI-KGNQESPKAT-GVF------TTLQ 1086
R G+P+ V S+ + L+P +Y + L + +G + P +T GV T
Sbjct: 2773 RDGRPQVMRVRGEESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVSTVGVTEDEAETTQAV 2832
Query: 1087 PGSSIPPYN---------TEVTETTIVITW-TPAPRIG-FKLGVRPSQGGEAPREVTSDS 1135
P ++ P N T+ T ++ ++W P + F + R G V
Sbjct: 2833 PTTTPEPPNKPRLGELTVTDATPDSLSLSWMVPEGQFDHFLVQYRNGDGQPKVVRVPGHE 2892
Query: 1136 GSIVVSGLTPGVEYVYTIQVLRDGQERDAPI----VNKVVTPLSPPTNLHLEA-----NP 1186
+ +SGL P +Y + GQ R PI V PT EA P
Sbjct: 2893 DGVTISGLEPDHKYKMNLYGFHGGQ-RVGPISVIGVTAAEEETPAPTEPSTEAPEPPEEP 2951
Query: 1187 DTGVLTVSWERSTTPDITGYRIT---------TTPTNGQQGNSLEEVVHADQSSCTFDNL 1237
G LTV+ ++PD T T + G V ++S T L
Sbjct: 2952 LLGELTVT---GSSPDSLSLSWTIPQGRFDSFTVQYKDRDGRPQVVRVRGEESEVTVGGL 3008
Query: 1238 SPGLEYNVSVYTV-----------------KDDKESVPISDTIIPEVP---QLTDLSFVD 1277
PG +Y + +Y + KD+ E+ T+ PE P +L +L+ D
Sbjct: 3009 EPGCKYKMHLYGLHEGQRVGPVSAVGVTAPKDEAETTQAVPTMTPEPPIKPRLGELTVTD 3068
Query: 1278 ITDSSIGLRWTPLNSST---IIGYRITVVAAGEG------IPIFEDFVDSSVGYYTVTGL 1328
T S+ L W ++ YR G+G +P ED V T++GL
Sbjct: 3069 ATPDSLSLSWMVPEGQFDHFLVQYR-----NGDGQPKAVRVPGHEDGV-------TISGL 3116
Query: 1329 EPGIDYDISVITLINGGESAPTTLTQQTA--VPPPTD----------------LRFTNIG 1370
EP Y +++ G P + T P PT+ L T
Sbjct: 3117 EPDHKYKMNLYGFHGGQRVGPVSAIGVTEEETPSPTEPSTEAPEAPEEPLLGELTVTGSS 3176
Query: 1371 PDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVS 1430
PD++ ++W P +F V+Y + V + ++ V + L PG +Y + +
Sbjct: 3177 PDSLSLSWTVPQG-RFDSFTVQYKDRDGQPQVVR--VRGEESEVTVGGLEPGRKYKMHLY 3233
Query: 1431 SVYEQHESTPLRGRQKTG-LDSPTGID-------FSDITANSFTVHWIAPRATITGYRIR 1482
++E P+ T L +P ++ + +T++S + W + + ++
Sbjct: 3234 GLHEGQRVGPVSTVGITAPLPTPLPVEPRLGELAVAAVTSDSVGLSWTVAQGPFDSFLVQ 3293
Query: 1483 HHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVAL-NGREESPLLIGQQSTVSDV 1541
+ G+P+ V ++ ++ L P +Y + L NG+ P+ + ++
Sbjct: 3294 YRDAQ--GQPQAVPVSGDLRAVAVSGLDPARKYKFLLFGLQNGKRHGPVPVEARTAPDTK 3351
Query: 1542 PR----DLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATIS 1597
P +L V ATP S+ +SW P + + Y + G +Q V ++ T+
Sbjct: 3352 PSPRLGELTVTDATPDSVGLSWTVPEGEFDSFVVQYKDKDGR--LQVVPVAANQREVTVQ 3409
Query: 1598 GLKPGVDYTITVYAVTGRGD-SPASSKPISINYRTEIDKP-SQMQVTDVQDNSISVKWLP 1655
GL+P Y +Y ++GR P S+ + E+ ++ V + +S+ + W
Sbjct: 3410 GLEPSRKYRFLLYGLSGRKRLGPISADSTTAPLEKELPPHLGELTVAEETSSSLRLSWTV 3469
Query: 1656 SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYV--------------V 1701
+ P + V ++ G + DQ +T+E L+P +Y V
Sbjct: 3470 AQGPFDSFVVQY--RDTDGQPRAVPVAADQRTVTVEDLEPGKKYKFLLYGLLGGKRLGPV 3527
Query: 1702 SVYAQNPSGESQPLVQTAVTNIDRPKG-----LAFTDVDVDSIKIAWESPQGQVSRYRVT 1756
S E P + A + P+ L TD DS++++W QG + V
Sbjct: 3528 SALGMTAPEEDTPAPELAPEAPEPPEEPRLGVLTVTDTTPDSMRLSWSVAQGPFDSFVVQ 3587
Query: 1757 YSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAI--- 1813
Y L DG++ + GL P + Y + LH+ PL +T +
Sbjct: 3588 YEDTNGQPQALLV--DGDQSKILISGLEPSTPYRFLLYGLHEGKRLGPLSAEGTTGLAPA 3645
Query: 1814 --------PAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVR--------VTPKEKTGPMK 1857
P + L T VT +SL W P + +R + P + +
Sbjct: 3646 GQTSEESRPRLSQLSVTDVTTSSLRLNWEAPPGAFDSFLLRFGVPSPSTLEPHPRPLLQR 3705
Query: 1858 EINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENV-SPPRRARVTDA 1916
E+ + S V+ L T Y +++Y L+ + QG TL V PR + ++
Sbjct: 3706 ELMVPGTRHSAVLRDLRSGTLYSLTLYGLRGPHKADSIQGTARTLSPVLESPRDLQFSEI 3765
Query: 1917 TETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYT 1976
ET+ ++W F+V A+G P + R+ + GL PG Y++ + +
Sbjct: 3766 RETSAKVNWMPPPSRADSFKVSYQLADGGEPQSVQVDGQARTQKLQGLIPGARYEVTVVS 3825
Query: 1977 LNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPR 2036
+ S P+ +T D P+ LR L T ++ W+PP+ + Y ++ PG+PP
Sbjct: 3826 VRGFEESEPLTGFLTTVPDGPTQLRALNLTEGFAVLHWKPPQNPVDTYDVQVTAPGAPPL 3885
Query: 2037 EVVPRPRPG-VTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELPQLVTLPHPN 2095
+ PG + + L T YT V L+ + P T
Sbjct: 3886 QA---ETPGSAVDYPLHDLVLHTNYTATVRGLRGPNLTSPASITFTT------------G 3930
Query: 2096 LHGPEILDVPSTVQKTPFVT---------------HPGYDTGNGIQLPG--TS----GQQ 2134
L P L+ +T +T H I LPG TS G
Sbjct: 3931 LEAPRDLEAKEVTPRTALLTWTEPPVRPAGYLLSFHTPGGQNQEILLPGGITSHQLLGLF 3990
Query: 2135 PSVGQQMIFEEHGFRRTTPPTTATPIRHRPR-PYPPNVGEEIQIG 2178
PS + + PP + + R P+P + GEE+Q G
Sbjct: 3991 PSTSYNARLQAMWGQSLLPPVSTSFTTGGLRIPFPRDCGEEMQNG 4035
Score = 296 bits (757), Expect = 2e-79
Identities = 435/2000 (21%), Positives = 750/2000 (37%), Gaps = 365/2000 (18%)
Query: 582 GVRYQCYCYGRGIGEWHCQPL--------QTYPSSSGPVEVF-ITETPSQPNSHPIQWNA 632
G +Y+ YG +G+ PL Q+ PS P + + T P+S + W
Sbjct: 1123 GRKYKFVLYGF-VGKKRHGPLVAEAKILPQSDPSPGTPPHLGNLWVTDPTPDSLHLSWTV 1181
Query: 633 PQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISI---QQYGH 689
P+ +++++R ++ GR + + G S+ + L P Y L I ++YG
Sbjct: 1182 PE-GQFDTFMVQYRDRD--GRPQVVPVEGPERSFVVSSLDPDHKYRFTLFGIANKKRYG- 1237
Query: 690 QEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSG 749
T T+ P PL+ +VT +T S +SW A
Sbjct: 1238 ------PLTADGTTAPERKEEPPRPEFLEQPLLGEL-TVTGVTPDSLRLSWTVAQGPFDS 1290
Query: 750 FRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQI---SEDGEQSLILSTS 806
F V+Y+ + +PQ + + V +P L P RKY +N+Y + G +S++ T+
Sbjct: 1291 FMVQYK--DAQGQPQAVPVAGDENEVTVPGLDPDRKYKMNLYGLRGRQRVGPESVVAKTA 1348
Query: 807 Q--------------TTAPDAPPDPTVDQVDDT-----SIVVRWSRPQAPITGYRIVYSP 847
T AP++P +P + ++ T S+ + W+ PQ + + Y
Sbjct: 1349 PQEDVDETPSPTELGTEAPESPEEPLLGELTVTGSSPDSLSLFWTVPQGSFDSFTVQYKD 1408
Query: 848 SVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVI-------QQETTG 900
+G + + + VT+ L+PG +Y + +Y + E Q PV Q+ET
Sbjct: 1409 R-DGRPRAVRVGGKESEVTVGGLEPGHKYKMHLYGLHEGQRVGPVSAVGVTAPQQEETPP 1467
Query: 901 TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT 960
S P +L +VT V + WT PE + ++ Q +P++ +
Sbjct: 1468 ATESPLEPRLGELTVTDVTPNSVGLSWTVPEGQFDSF---IVQYKDKDGQPQVVPVAADQ 1524
Query: 961 FAEVT--GLSPGVTYYFKVFAVSHGRESKPLT------------AQQTTKLDAPTNLQFV 1006
EVT L P Y ++ + G+ PL+ A + +K L +
Sbjct: 1525 -REVTVYNLEPERKYKMNMYGLHDGQRMGPLSVVIVTAPLPPAPATEASKPPLEPRLGEL 1583
Query: 1007 NETDST---VLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYT 1063
TD T V + WT P + + + R GQP+ V + + +L+P+ +Y
Sbjct: 1584 TVTDITPDSVGLSWTVPEGEFDSF-VVQYKDRDGQPQVVPVAADQREVTIPDLEPSRKYK 1642
Query: 1064 VSLVAIK-GNQESPKATGVFTTLQPGSS--IPP-----YNTEVTETTIVITWTPAPRIGF 1115
L I+ G + SP + T + +S PP + T+ T ++ ++WT P F
Sbjct: 1643 FLLFGIQDGKRRSPVSVEAKTVARGDASPGAPPRLGELWVTDPTPDSLRLSWT-VPEGQF 1701
Query: 1116 KLGVRPSQGGEAPR--EVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVT- 1172
V + + P+ V S+ V+ L G +Y + + L G++R P+ T
Sbjct: 1702 DSFVVQFKDKDGPQVVPVEGHERSVTVTPLDAGRKYRFLLYGLL-GKKRHGPLTADGTTE 1760
Query: 1173 ------------PLSPPTNLHLEANPDT-GVLTVSWERSTTPD--ITGYRITTTPTNGQQ 1217
P P L+ T + +SW T P+ + + +GQ
Sbjct: 1761 ARSAMDDTGTKRPPKPRLGEELQVTTVTQNSVGLSW---TVPEGQFDSFVVQYKDRDGQ- 1816
Query: 1218 GNSLEEVVHADQS--SCTFDNLSPGLEYNVSVYTVKDDKESVPISDTII----------- 1264
+VV + S + L P Y + +Y + K PIS I
Sbjct: 1817 ----PQVVPVEGSLREVSVPGLDPAHRYKLLLYGLHHGKRVGPISAVAITAGREETETET 1872
Query: 1265 -------PEVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIFEDFVD 1317
PE P L +L+ + T ++ L W + + I + + +
Sbjct: 1873 TAPTPPAPE-PHLGELTVEEATSHTLHLSWM-VTEGEFDSFEIQYTDRDGQLQMVR--IG 1928
Query: 1318 SSVGYYTVTGLEPGIDYDISVITLINGGESAP------TTLTQQTAVPPPT--------- 1362
T++GLE Y +++ +G P T ++ PPT
Sbjct: 1929 GDRNDITLSGLESDHRYLVTLYGFSDGKHVGPVHVEALTVPEEEKPSEPPTATPEPPIKP 1988
Query: 1363 ---DLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNL 1419
+L T+ PD++ ++W P +FLV+Y + + + + V ++ L
Sbjct: 1989 RLGELTVTDATPDSLSLSWTVPEG-QFDHFLVQYR--NGDGQPKAVRVPGHEEGVTISGL 2045
Query: 1420 LPGTEY--------------VVSVSSVYEQHESTPLRGRQKTGLDSPT------GIDFSD 1459
P +Y VSV V E TP P + +
Sbjct: 2046 EPDHKYKMNLYGFHGGQRMGPVSVVGVTAAEEETPSPTEPSMEAPEPAEEPLLGELTVTG 2105
Query: 1460 ITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSI 1519
+ +S ++ W P+ + +++ GRP+ RV + +T+ L PG +Y + +
Sbjct: 2106 SSPDSLSLSWTVPQGRFDSFTVQYKDR--DGRPQVVRVGGEESEVTVGGLEPGRKYKMHL 2163
Query: 1520 VALN-GREESPL-LIGQQSTVSDVP---------RDLEVVAATPTSLLISWDAPAVTVRY 1568
L+ GR P+ +G + + P + V T SL +SW P +
Sbjct: 2164 YGLHEGRRVGPVSAVGVTAPEEESPDAPLAKLRLGQMTVRDITSDSLSLSWTVPEGQFDH 2223
Query: 1569 YRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAV-TGRGDSPASSKPISI 1627
+ + + G+ + VPG + TISGL+P Y + +Y G+ P S+ ++
Sbjct: 2224 FLVQF--KNGDGQPKAVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPVSAVGLTA 2281
Query: 1628 NYRTEIDKPS----------------QMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKN 1671
+ E P+ ++ VTD +S+S+ W + V KN
Sbjct: 2282 PGKDEEMAPASTEPPTPEPPIKPRLEELTVTDATPDSLSLSWTVPEGQFDHFLVQY--KN 2339
Query: 1672 GPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVT---------- 1721
G G K + +TI GL+P +Y +++Y + P+ VT
Sbjct: 2340 GDGQPKATRVPGHEDRVTISGLEPDNKYKMNLYGFHGGQRVGPVSAIGVTAAEEETPSPT 2399
Query: 1722 --NIDRPK--------GLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAP 1771
+++ P+ L T DS+ ++W PQG+ + V Y DG ++
Sbjct: 2400 EPSMEAPEPPEEPLLGELTVTGSSPDSLSLSWTVPQGRFDSFTVQYKD-RDGRPQVVRV- 2457
Query: 1772 DGEEDTAELQGLRPGSEY-----------------TVSVVALHDDMESQPLIGTQSTAIP 1814
GEE + GL PG +Y TV V A +D++ P T P
Sbjct: 2458 GGEESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVSTVGVTAPQEDVDETPSPTEPGTEAP 2517
Query: 1815 APT------DLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSV 1868
P +L T +P SLS WT P + + V+ K++ G + + + S V
Sbjct: 2518 GPPEEPLLGELTVTGSSPDSLSLSWTVPQGRFDSFTVQY--KDRDGRPQAVRVGGQESKV 2575
Query: 1869 VVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENV-----------SPPRRAR----- 1912
V GL KY++ +Y L + P V T + PP + R
Sbjct: 2576 TVRGLEPGRKYKMHLYGLHEGRRLGPVSAVGVTEDEAETTQAVPTMTPEPPIKPRLGELT 2635
Query: 1913 VTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKI 1972
+TDAT ++++SW F V +GQ R + TI+GL+P YK+
Sbjct: 2636 MTDATPDSLSLSWTVPEGQFDHFLVQYRNGDGQPKAVR-VPGHEDGVTISGLEPDHKYKM 2694
Query: 1973 YLYTLNDNARSSPVVIDASTA------------IDAP--------SNLRFLATTPNSLLV 2012
LY + R P+ + TA +AP L ++P+SL +
Sbjct: 2695 NLYGFHGGQRVGPISVIGVTAAEEETPSPTELSTEAPEPPEEPLLGELTVTGSSPDSLSL 2754
Query: 2013 SWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQK 2072
SW P+ + ++Y+ P+ V R R +E T+ GLEPG +Y +++ L ++
Sbjct: 2755 SWTIPQGHFDSFTVQYKDRDGRPQ--VMRVRGEESEVTVGGLEPGRKYKMHLYGLHEGRR 2812
Query: 2073 SEPL--IG-----RKKTDELPQLVTLP--HPNLHGPEILDVPSTVQKTPFVTHPG----- 2118
P+ +G + T +P P P L + D ++ G
Sbjct: 2813 VGPVSTVGVTEDEAETTQAVPTTTPEPPNKPRLGELTVTDATPDSLSLSWMVPEGQFDHF 2872
Query: 2119 ---YDTGNG----IQLPG------TSGQQPSVGQQM-IFEEHGFRRTTPPTT-------- 2156
Y G+G +++PG SG +P +M ++ HG +R P +
Sbjct: 2873 LVQYRNGDGQPKVVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPISVIGVTAAEE 2932
Query: 2157 ATPIRHRPRPYPPNVGEEIQIGHIPREDVDYHLYPHGPGLNPNASTGQEALSQTTISWAP 2216
TP P P EE +G + G +P++ ++SW
Sbjct: 2933 ETPAPTEPSTEAPEPPEEPLLGELT-----------VTGSSPDS---------LSLSWTI 2972
Query: 2217 FQDTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHKVRE 2276
Q + + D P RV G + T+ GL G Y + + L + QR
Sbjct: 2973 PQGRFD-SFTVQYKDRDGRPQVVRVRGEESEVTVGGLEPGCKYKMHLYGLHEGQR----- 3026
Query: 2277 EVVTVGNSVNEGLNQPTDDS 2296
VG G+ P D++
Sbjct: 3027 ----VGPVSAVGVTAPKDEA 3042
Score = 294 bits (753), Expect = 6e-79
Identities = 379/1729 (21%), Positives = 635/1729 (36%), Gaps = 315/1729 (18%)
Query: 616 ITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGV 675
+T T P+S + W P+ ++++++ ++ G+ + + TI L+P
Sbjct: 1583 LTVTDITPDSVGLSWTVPE-GEFDSFVVQYKDRD--GQPQVVPVAADQREVTIPDLEPSR 1639
Query: 676 VYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASS 735
Y+ L IQ D S + G+ +P +P VT+ T S
Sbjct: 1640 KYKFLLFGIQ----------DGKRRSPVSVEAKTVARGDASPGAPPRLGELWVTDPTPDS 1689
Query: 736 FVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISE 795
+SW F V+++ + D PQ + + SV + L GRKY +Y +
Sbjct: 1690 LRLSWTVPEGQFDSFVVQFK---DKDGPQVVPVEGHERSVTVTPLDAGRKYRFLLYGLLG 1746
Query: 796 DGEQSLILSTSQTTAPDA--------PPDPTVDQ------VDDTSIVVRWSRPQAPITGY 841
+ + T A A PP P + + V S+ + W+ P+ +
Sbjct: 1747 KKRHGPLTADGTTEARSAMDDTGTKRPPKPRLGEELQVTTVTQNSVGLSWTVPEGQFDSF 1806
Query: 842 RIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGT 901
+ Y +G + + + V++ L P +Y + +Y + + P+ T G
Sbjct: 1807 VVQYKDR-DGQPQVVPVEGSLREVSVPGLDPAHRYKLLLYGLHHGKRVGPISAVAITAGR 1865
Query: 902 PRSDT--------VPSPR--DLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHG 951
++T P P +L E T + + W VT D + G
Sbjct: 1866 EETETETTAPTPPAPEPHLGELTVEEATSHTLHLSWM-----VTEGEFDSFEIQYTDRDG 1920
Query: 952 Q----RLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKP-----LTAQQTTKLDAPTN 1002
Q R+ RN ++GL Y ++ S G+ P LT + K P
Sbjct: 1921 QLQMVRIGGDRNDIT-LSGLESDHRYLVTLYGFSDGKHVGPVHVEALTVPEEEKPSEPPT 1979
Query: 1003 -------------LQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVS 1049
L + T ++ + WT P Q + L GQP+ V
Sbjct: 1980 ATPEPPIKPRLGELTVTDATPDSLSLSWTVPEGQFDHF-LVQYRNGDGQPKAVRVPGHEE 2038
Query: 1050 KYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTL---------QPGSSIP-----PYN 1095
+ L+P +Y ++L G Q + V T +P P P
Sbjct: 2039 GVTISGLEPDHKYKMNLYGFHGGQRMGPVSVVGVTAAEEETPSPTEPSMEAPEPAEEPLL 2098
Query: 1096 TEVTET-----TIVITWT-PAPRI-GFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVE 1148
E+T T ++ ++WT P R F + + G V + + V GL PG +
Sbjct: 2099 GELTVTGSSPDSLSLSWTVPQGRFDSFTVQYKDRDGRPQVVRVGGEESEVTVGGLEPGRK 2158
Query: 1149 YVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITG--Y 1206
Y + L +G+ R P+ VT E +PD + + + T DIT
Sbjct: 2159 YKMHLYGLHEGR-RVGPVSAVGVTAPE-------EESPDAPLAKLRLGQMTVRDITSDSL 2210
Query: 1207 RITTTPTNGQQGNSLEEVVHAD-----------QSSCTFDNLSPGLEYNVSVYTVKDDKE 1255
++ T GQ + L + + D + T L P +Y +++Y +
Sbjct: 2211 SLSWTVPEGQFDHFLVQFKNGDGQPKAVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQR 2270
Query: 1256 SVPISDTII---------------------PEVPQLTDLSFVDITDSSIGLRWTPLNSST 1294
P+S + P P+L +L+ D T S+ L WT
Sbjct: 2271 VGPVSAVGLTAPGKDEEMAPASTEPPTPEPPIKPRLEELTVTDATPDSLSLSWTVPEGQ- 2329
Query: 1295 IIGYRITVVAAGEG------IPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESA 1348
+ + G+G +P ED V T++GLEP Y +++ G
Sbjct: 2330 -FDHFLVQYKNGDGQPKATRVPGHEDRV-------TISGLEPDNKYKMNLYGFHGGQRVG 2381
Query: 1349 PTTLTQQTAV----PPPTD----------------LRFTNIGPDTMRVTWAPPPSIDLTN 1388
P + TA P PT+ L T PD++ ++W P +
Sbjct: 2382 PVSAIGVTAAEEETPSPTEPSMEAPEPPEEPLLGELTVTGSSPDSLSLSWTVPQG-RFDS 2440
Query: 1389 FLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEY-----------------VVSVSS 1431
F V+Y V + ++ V + L PG +Y V V++
Sbjct: 2441 FTVQYKDRDGRPQVVR--VGGEESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVSTVGVTA 2498
Query: 1432 VYEQHESTPLRGRQKTGLDSPTG------IDFSDITANSFTVHWIAPRATITGYRIRHHP 1485
E + TP T P + + + +S ++ W P+ + +++
Sbjct: 2499 PQEDVDETPSPTEPGTEAPGPPEEPLLGELTVTGSSPDSLSLSWTVPQGRFDSFTVQYKD 2558
Query: 1486 EHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN-GREESPL-LIG----QQSTVS 1539
GRP+ RV + +T+ L PG +Y + + L+ GR P+ +G + T
Sbjct: 2559 R--DGRPQAVRVGGQESKVTVRGLEPGRKYKMHLYGLHEGRRLGPVSAVGVTEDEAETTQ 2616
Query: 1540 DVPR------------DLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTV 1587
VP +L + ATP SL +SW P ++ + Y G+ + V
Sbjct: 2617 AVPTMTPEPPIKPRLGELTMTDATPDSLSLSWTVPEGQFDHFLVQY--RNGDGQPKAVRV 2674
Query: 1588 PGSKSTATISGLKPGVDYTITVYAVTGR---------GDSPASSK-PISINYRTEIDKP- 1636
PG + TISGL+P Y + +Y G G + A + P TE +P
Sbjct: 2675 PGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPISVIGVTAAEEETPSPTELSTEAPEPP 2734
Query: 1637 -----SQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIE 1691
++ VT +S+S+ W + V ++G P + G +++E+T+
Sbjct: 2735 EEPLLGELTVTGSSPDSLSLSWTIPQGHFDSFTVQYKDRDGR-PQVMRVRG-EESEVTVG 2792
Query: 1692 GLQPTVEYVVSVYAQNPSGESQPLVQTAVT------------------NIDRPKGLAFTD 1733
GL+P +Y + +Y + P+ VT N R L TD
Sbjct: 2793 GLEPGRKYKMHLYGLHEGRRVGPVSTVGVTEDEAETTQAVPTTTPEPPNKPRLGELTVTD 2852
Query: 1734 VDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSV 1793
DS+ ++W P+GQ + V Y + DG ++ P G ED + GL P +Y +++
Sbjct: 2853 ATPDSLSLSWMVPEGQFDHFLVQYRNG-DGQPKVVRVP-GHEDGVTISGLEPDHKYKMNL 2910
Query: 1794 VALHDDMESQPLIGTQSTAI----PAPTD----------------LKFTQVTPTSLSAQW 1833
H P+ TA PAPT+ L T +P SLS W
Sbjct: 2911 YGFHGGQRVGPISVIGVTAAEEETPAPTEPSTEAPEPPEEPLLGELTVTGSSPDSLSLSW 2970
Query: 1834 TPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSR 1893
T P + + V+ K++ G + + + + S V V GL KY++ +Y L +
Sbjct: 2971 TIPQGRFDSFTVQY--KDRDGRPQVVRVRGEESEVTVGGLEPGCKYKMHLYGLHEGQRVG 3028
Query: 1894 PAQGVVTTLEN-------------VSPPRRAR-----VTDATETTITISWRTKTETITGF 1935
P V T PP + R VTDAT ++++SW F
Sbjct: 3029 PVSAVGVTAPKDEAETTQAVPTMTPEPPIKPRLGELTVTDATPDSLSLSWMVPEGQFDHF 3088
Query: 1936 QVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAID 1995
V +GQ R + TI+GL+P YK+ LY + R PV T +
Sbjct: 3089 LVQYRNGDGQPKAVR-VPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPVSAIGVTEEE 3147
Query: 1996 APS------------------NLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPRE 2037
PS L ++P+SL +SW P+ R + ++Y+ P+
Sbjct: 3148 TPSPTEPSTEAPEAPEEPLLGELTVTGSSPDSLSLSWTVPQGRFDSFTVQYKDRDGQPQV 3207
Query: 2038 VVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELP 2086
V R R +E T+ GLEPG +Y +++ L Q+ P+ T LP
Sbjct: 3208 V--RVRGEESEVTVGGLEPGRKYKMHLYGLHEGQRVGPVSTVGITAPLP 3254
Score = 283 bits (725), Expect = 1e-75
Identities = 418/1893 (22%), Positives = 698/1893 (36%), Gaps = 312/1893 (16%)
Query: 629 QWNAPQPSHISKYILRWRPKNSVGRWK-EATIPGHLNSYTIKGLKPGVVYEGQLISIQQY 687
+W P P + Y +++ P A +P ++Y +GL PG Y
Sbjct: 768 EWT-PAPGPVDAYEIQFIPTTEGASPPFTARVPSSASAYDQRGLAPGQEY---------- 816
Query: 688 GHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTV 747
+VT TS P + T P V +T ++ + W+ V
Sbjct: 817 ---QVTVRALRGTSWGLPASKTITTMIDGP------QDLRVVAVTPTTLELGWLRPQAEV 867
Query: 748 SGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNV---------YQIS---E 795
F V Y G++ L++P A + DL+PG +Y+V V Y S
Sbjct: 868 DRFVVSY--VSAGNQRVRLEVPPEADGTLLTDLMPGVEYVVTVTAERGRAVSYPASVRAN 925
Query: 796 DGEQSL-ILSTSQTTAPDAPPD------PTVDQ------------VDDTS-IVVRWSRPQ 835
G L +L T+ P P P + Q D+T + V W+
Sbjct: 926 TGSSPLGLLGTTDEPPPSGPSTTQGAQAPLLQQRPQELGELRVLGRDETGRLRVVWTAQP 985
Query: 836 APITGYRI-VYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEE-NQESTPVV 893
+++ + P G+ E+ LP + PG Y ++++ V + S P++
Sbjct: 986 DTFAYFQLRMRVPEGPGAHEEV-LPGDVRQALVPPPPPGTPYELSLHGVPPGGKPSDPII 1044
Query: 894 IQ----QETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRV-----DVIPV 944
Q ++ +S P +L + T + + WT PE + + D P
Sbjct: 1045 YQGIMDKDEEKPGKSSGPPRLGELTVTDRTSDSLLLRWTVPEGEFDSFVIQYKDRDGQPQ 1104
Query: 945 NLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTA------QQTTKLD 998
+P E QR A +T L PG Y F ++ + PL A Q
Sbjct: 1105 VVPVEGPQR-------SAVITSLDPGRKYKFVLYGFVGKKRHGPLVAEAKILPQSDPSPG 1157
Query: 999 APT---NLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRN 1055
P NL + T ++ + WT P Q + + R G+P+ V + + +
Sbjct: 1158 TPPHLGNLWVTDPTPDSLHLSWTVPEGQFDTFMVQY-RDRDGRPQVVPVEGPERSFVVSS 1216
Query: 1056 LQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYN-------------TEVTETT 1102
L P +Y +L I + T TT PP T VT +
Sbjct: 1217 LDPDHKYRFTLFGIANKKRYGPLTADGTTAPERKEEPPRPEFLEQPLLGELTVTGVTPDS 1276
Query: 1103 IVITWTPA--PRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQ 1160
+ ++WT A P F + + +QG V D + V GL P +Y + LR G+
Sbjct: 1277 LRLSWTVAQGPFDSFMVQYKDAQGQPQAVPVAGDENEVTVPGLDPDRKYKMNLYGLR-GR 1335
Query: 1161 ERDAPIVNKVVTPLSP---------PTNLHLEA-----NPDTGVLTVSWERSTTPDITGY 1206
+R P VV +P PT L EA P G LTV+ ++PD
Sbjct: 1336 QRVGP--ESVVAKTAPQEDVDETPSPTELGTEAPESPEEPLLGELTVT---GSSPDSLSL 1390
Query: 1207 RIT---------TTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESV 1257
T T + G V +S T L PG +Y + +Y + + +
Sbjct: 1391 FWTVPQGSFDSFTVQYKDRDGRPRAVRVGGKESEVTVGGLEPGHKYKMHLYGLHEGQRVG 1450
Query: 1258 PIS--------------DTIIPEVPQLTDLSFVDITDSSIGLRWTPLN---SSTIIGYRI 1300
P+S T P P+L +L+ D+T +S+GL WT S I+ Y+
Sbjct: 1451 PVSAVGVTAPQQEETPPATESPLEPRLGELTVTDVTPNSVGLSWTVPEGQFDSFIVQYK- 1509
Query: 1301 TVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAVPP 1360
+ +P+ D + TV LEP Y +++ L +G P ++ TA P
Sbjct: 1510 DKDGQPQVVPVAADQRE-----VTVYNLEPERKYKMNMYGLHDGQRMGPLSVVIVTAPLP 1564
Query: 1361 PT---------------DLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAEL 1405
P +L T+I PD++ ++W P + +F+V+Y + V +
Sbjct: 1565 PAPATEASKPPLEPRLGELTVTDITPDSVGLSWTVPEG-EFDSFVVQYKDRDGQPQV--V 1621
Query: 1406 SISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKT---GLDSPTG------ID 1456
++ V + +L P +Y + + + +P+ KT G SP +
Sbjct: 1622 PVAADQREVTIPDLEPSRKYKFLLFGIQDGKRRSPVSVEAKTVARGDASPGAPPRLGELW 1681
Query: 1457 FSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYV 1516
+D T +S + W P + ++ + P+ V S+T+T L G +Y
Sbjct: 1682 VTDPTPDSLRLSWTVPEGQFDSFVVQFKDK---DGPQVVPVEGHERSVTVTPLDAGRKYR 1738
Query: 1517 VSIVALNGREESPLLIGQ-----QSTVSDV-------PR---DLEVVAATPTSLLISWDA 1561
+ L G++ L +S + D PR +L+V T S+ +SW
Sbjct: 1739 FLLYGLLGKKRHGPLTADGTTEARSAMDDTGTKRPPKPRLGEELQVTTVTQNSVGLSWTV 1798
Query: 1562 PAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAV-TGRGDSPA 1620
P + + Y + G Q V GS ++ GL P Y + +Y + G+ P
Sbjct: 1799 PEGQFDSFVVQYKDRDGQP--QVVPVEGSLREVSVPGLDPAHRYKLLLYGLHHGKRVGPI 1856
Query: 1621 SSKPISI---NYRTEIDKPS---------QMQVTDVQDNSISVKWLPSSSPVTGYRVTTT 1668
S+ I+ TE P+ ++ V + +++ + W+ + + + T
Sbjct: 1857 SAVAITAGREETETETTAPTPPAPEPHLGELTVEEATSHTLHLSWMVTEGEFDSFEIQYT 1916
Query: 1669 PKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPK- 1727
++ G + G D+ ++T+ GL+ Y+V++Y + P+ A+T + K
Sbjct: 1917 DRD--GQLQMVRIGGDRNDITLSGLESDHRYLVTLYGFSDGKHVGPVHVEALTVPEEEKP 1974
Query: 1728 -----------------GLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPA 1770
L TD DS+ ++W P+GQ + V Y + DG +
Sbjct: 1975 SEPPTATPEPPIKPRLGELTVTDATPDSLSLSWTVPEGQFDHFLVQYRN-GDGQPKAVRV 2033
Query: 1771 PDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTA----IPAPT--------- 1817
P G E+ + GL P +Y +++ H P+ TA P+PT
Sbjct: 2034 P-GHEEGVTISGLEPDHKYKMNLYGFHGGQRMGPVSVVGVTAAEEETPSPTEPSMEAPEP 2092
Query: 1818 -------DLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVV 1870
+L T +P SLS WT P + + V+ K++ G + + + + S V V
Sbjct: 2093 AEEPLLGELTVTGSSPDSLSLSWTVPQGRFDSFTVQY--KDRDGRPQVVRVGGEESEVTV 2150
Query: 1871 SGLMVATKYEVSVYALKDTLTSRPAQGV-VTTLENVSPPR--------RARVTDATETTI 1921
GL KY++ +Y L + P V VT E SP + V D T ++
Sbjct: 2151 GGLEPGRKYKMHLYGLHEGRRVGPVSAVGVTAPEEESPDAPLAKLRLGQMTVRDITSDSL 2210
Query: 1922 TISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNA 1981
++SW F V +GQ R + TI+GL+P YK+ LY +
Sbjct: 2211 SLSWTVPEGQFDHFLVQFKNGDGQPKAVR-VPGHEDGVTISGLEPDHKYKMNLYGFHGGQ 2269
Query: 1982 RSSPV-------------VIDASTAIDAP--------SNLRFLATTPNSLLVSWQPPRAR 2020
R PV + AST P L TP+SL +SW P +
Sbjct: 2270 RVGPVSAVGLTAPGKDEEMAPASTEPPTPEPPIKPRLEELTVTDATPDSLSLSWTVPEGQ 2329
Query: 2021 ITGYIIKYEK-PGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGR 2079
++++Y+ G P VP V TI+GLEP +Y + + Q+ P+
Sbjct: 2330 FDHFLVQYKNGDGQPKATRVPGHEDRV---TISGLEPDNKYKMNLYGFHGGQRVGPVSAI 2386
Query: 2080 KKTDELPQLVTLPHPNLHGPEILDVPSTVQKTPFVTHP-----GYDTGNGIQLPGTSGQQ 2134
T + + P++ PE + P + T + P + G T +
Sbjct: 2387 GVTAAEEETPSPTEPSMEAPEPPEEPLLGELTVTGSSPDSLSLSWTVPQGRFDSFTVQYK 2446
Query: 2135 PSVGQQMIFEEHGFRRTTPPTTATPIR-HRPRPYPPNVGEEI----QIG-HIPREDVDYH 2188
G+ + G P R ++ Y + G + +G P+EDVD
Sbjct: 2447 DRDGRPQVVRVGGEESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVSTVGVTAPQEDVDET 2506
Query: 2189 LYPHGPGLNPNASTGQEALSQTTI----------SWAPFQDTSEYIISCHPVGTDEEPLQ 2238
P PG + L + T+ SW Q + + D P
Sbjct: 2507 PSPTEPGTEAPGPPEEPLLGELTVTGSSPDSLSLSWTVPQGRFD-SFTVQYKDRDGRPQA 2565
Query: 2239 FRVPGTSTSATLTGLTRGATYNIIVEALKDQQR 2271
RV G + T+ GL G Y + + L + +R
Sbjct: 2566 VRVGGQESKVTVRGLEPGRKYKMHLYGLHEGRR 2598
Score = 269 bits (688), Expect = 2e-71
Identities = 403/1792 (22%), Positives = 669/1792 (37%), Gaps = 294/1792 (16%)
Query: 740 WVSASDTVSGFRVEYELSEEGDEPQYLD-LPSTATSVNIPDLLPGRKYIVNVYQISEDGE 798
W A V + +++ + EG P + +PS+A++ + L PG++Y V V +
Sbjct: 769 WTPAPGPVDAYEIQFIPTTEGASPPFTARVPSSASAYDQRGLAPGQEYQVTVRAL-RGTS 827
Query: 799 QSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNL 858
L S + TT D P D V V T++ + W RPQA + + + Y S L +
Sbjct: 828 WGLPASKTITTMIDGPQDLRVVAVTPTTLELGWLRPQAEVDRFVVSYV-SAGNQRVRLEV 886
Query: 859 PETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTP------RSDTVPS--- 909
P A+ L+DL PGV+Y +T+ A S P ++ T +P + PS
Sbjct: 887 PPEADGTLLTDLMPGVEYVVTVTAERGRAVSYPASVRANTGSSPLGLLGTTDEPPPSGPS 946
Query: 910 -------------PRDLQFVEVTDVKVT----IMWTPPESAVTGYRVDVIPVNLPGEHGQ 952
P++L + V T ++WT +++ + PG H +
Sbjct: 947 TTQGAQAPLLQQRPQELGELRVLGRDETGRLRVVWTAQPDTFAYFQLRMRVPEGPGAHEE 1006
Query: 953 RLPISRNTFAEVTGLSPGVTYYFKVFAVSHG-RESKPLTAQ--------QTTKLDAPTNL 1003
LP A V PG Y + V G + S P+ Q + K P L
Sbjct: 1007 VLPGDVRQ-ALVPPPPPGTPYELSLHGVPPGGKPSDPIIYQGIMDKDEEKPGKSSGPPRL 1065
Query: 1004 QFVNETDST---VLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPAS 1060
+ TD T +L+RWT P + + + R GQP+ V + +L P
Sbjct: 1066 GELTVTDRTSDSLLLRWTVPEGEFDSFVIQYK-DRDGQPQVVPVEGPQRSAVITSLDPGR 1124
Query: 1061 EYTVSLVAIKGNQESPKATG---VFTTLQPGSSIPPYN-----TEVTETTIVITWT-PAP 1111
+Y L G + + P PP+ T+ T ++ ++WT P
Sbjct: 1125 KYKFVLYGFVGKKRHGPLVAEAKILPQSDPSPGTPPHLGNLWVTDPTPDSLHLSWTVPEG 1184
Query: 1112 RIG-FKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKV 1170
+ F + R G V S VVS L P +Y +T+ + + ++R P+
Sbjct: 1185 QFDTFMVQYRDRDGRPQVVPVEGPERSFVVSSLDPDHKYRFTLFGIAN-KKRYGPLTADG 1243
Query: 1171 VTPLS----PPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQ---------- 1216
T PP LE P G LTV+ TPD R++ T G
Sbjct: 1244 TTAPERKEEPPRPEFLE-QPLLGELTVT---GVTPD--SLRLSWTVAQGPFDSFMVQYKD 1297
Query: 1217 -QGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVK-----------------DDKESVP 1258
QG V D++ T L P +Y +++Y ++ +D + P
Sbjct: 1298 AQGQPQAVPVAGDENEVTVPGLDPDRKYKMNLYGLRGRQRVGPESVVAKTAPQEDVDETP 1357
Query: 1259 ISDTI------IPEVPQLTDLSFVDITDSSIGLRWT-PLNS--STIIGYRITVVAAGEGI 1309
+ PE P L +L+ + S+ L WT P S S + Y+ +G
Sbjct: 1358 SPTELGTEAPESPEEPLLGELTVTGSSPDSLSLFWTVPQGSFDSFTVQYKDR-----DGR 1412
Query: 1310 PIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPT-----TLTQQTAVPPPTD- 1363
P V TV GLEPG Y + + L G P T QQ PP T+
Sbjct: 1413 PRAVR-VGGKESEVTVGGLEPGHKYKMHLYGLHEGQRVGPVSAVGVTAPQQEETPPATES 1471
Query: 1364 --------LRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVV 1415
L T++ P+++ ++W P +F+V+Y + V + ++ V
Sbjct: 1472 PLEPRLGELTVTDVTPNSVGLSWTVPEG-QFDSFIVQYKDKDGQPQV--VPVAADQREVT 1528
Query: 1416 LTNLLPGTEYVVSVSSVYEQHESTPLR--------------GRQKTGLDSPTG-IDFSDI 1460
+ NL P +Y +++ +++ PL K L+ G + +DI
Sbjct: 1529 VYNLEPERKYKMNMYGLHDGQRMGPLSVVIVTAPLPPAPATEASKPPLEPRLGELTVTDI 1588
Query: 1461 TANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIV 1520
T +S + W P + +++ G+P+ V + +T+ +L P +Y +
Sbjct: 1589 TPDSVGLSWTVPEGEFDSFVVQYKDR--DGQPQVVPVAADQREVTIPDLEPSRKYKFLLF 1646
Query: 1521 AL-NGREESPLLIGQQSTVSD------VPR--DLEVVAATPTSLLISWDAPAVTVRYYRI 1571
+ +G+ SP+ + ++ PR +L V TP SL +SW P + +
Sbjct: 1647 GIQDGKRRSPVSVEAKTVARGDASPGAPPRLGELWVTDPTPDSLRLSWTVPEGQFDSFVV 1706
Query: 1572 TYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRT 1631
+ + G V V G + + T++ L G Y +Y + G+ + + R+
Sbjct: 1707 QFKDKDGPQVVP---VEGHERSVTVTPLDAGRKYRFLLYGLLGKKRHGPLTADGTTEARS 1763
Query: 1632 EID--------KP---SQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKT 1680
+D KP ++QVT V NS+ + W + V ++G P
Sbjct: 1764 AMDDTGTKRPPKPRLGEELQVTTVTQNSVGLSWTVPEGQFDSFVVQYKDRDGQ-PQVVPV 1822
Query: 1681 AGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVT----------NIDRPKG-- 1728
G E+++ GL P Y + +Y + P+ A+T P
Sbjct: 1823 EG-SLREVSVPGLDPAHRYKLLLYGLHHGKRVGPISAVAITAGREETETETTAPTPPAPE 1881
Query: 1729 -----LAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGL 1783
L + ++ ++W +G+ + + Y+ DG ++ G+ + L GL
Sbjct: 1882 PHLGELTVEEATSHTLHLSWMVTEGEFDSFEIQYTD-RDGQLQMVRI-GGDRNDITLSGL 1939
Query: 1784 RPGSEYTVSVVALHDDMESQPLI------------GTQSTAIPAPT------DLKFTQVT 1825
Y V++ D P+ TA P P +L T T
Sbjct: 1940 ESDHRYLVTLYGFSDGKHVGPVHVEALTVPEEEKPSEPPTATPEPPIKPRLGELTVTDAT 1999
Query: 1826 PTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYA 1885
P SLS WT P Q + V+ + G K + + V +SGL KY++++Y
Sbjct: 2000 PDSLSLSWTVPEGQFDHFLVQY--RNGDGQPKAVRVPGHEEGVTISGLEPDHKYKMNLYG 2057
Query: 1886 LKDTLTSRPAQGV-VTTLENVSP---------PRRAR--------VTDATETTITISWRT 1927
P V VT E +P P A VT ++ ++++SW
Sbjct: 2058 FHGGQRMGPVSVVGVTAAEEETPSPTEPSMEAPEPAEEPLLGELTVTGSSPDSLSLSWTV 2117
Query: 1928 KTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVV 1987
F V +G+ + R + + T+ GL+PG YK++LY L++ R PV
Sbjct: 2118 PQGRFDSFTVQYKDRDGRPQVVR-VGGEESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVS 2176
Query: 1988 IDASTA-----IDAP------SNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPR 2036
TA DAP + T +SL +SW P + ++++++ P+
Sbjct: 2177 AVGVTAPEEESPDAPLAKLRLGQMTVRDITSDSLSLSWTVPEGQFDHFLVQFKNGDGQPK 2236
Query: 2037 EV-VPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEP-----LIGRKKTDELPQLVT 2090
V VP GV TI+GLEP +Y + + Q+ P L K +E+ T
Sbjct: 2237 AVRVPGHEDGV---TISGLEPDHKYKMNLYGFHGGQRVGPVSAVGLTAPGKDEEMAPAST 2293
Query: 2091 LP-------HPNLH-------GPEILDVPSTVQKTPFVTH--PGYDTGNG----IQLPG- 2129
P P L P+ L + TV + F H Y G+G ++PG
Sbjct: 2294 EPPTPEPPIKPRLEELTVTDATPDSLSLSWTVPEGQF-DHFLVQYKNGDGQPKATRVPGH 2352
Query: 2130 -----TSGQQPSVGQQM-IFEEHGFRRTTPPTTATPIRHRPRPYPPNVGEEIQIGHIPRE 2183
SG +P +M ++ HG +R P +A + P ++ P E
Sbjct: 2353 EDRVTISGLEPDNKYKMNLYGFHGGQR-VGPVSAIGVTAAEEETPSPTEPSMEAPEPPEE 2411
Query: 2184 DVDYHLYPHGPGLNPNASTGQEALSQTTISWAPFQDTSEYIISCHPVGTDEEPLQFRVPG 2243
P L TG ++SW Q + + D P RV G
Sbjct: 2412 ----------PLLGELTVTGSSP-DSLSLSWTVPQGRFD-SFTVQYKDRDGRPQVVRVGG 2459
Query: 2244 TSTSATLTGLTRGATYNIIVEALKDQQRHKVREEVVTVGNSVNEGLNQPTDD 2295
+ T+ GL G Y + + L + +R VG G+ P +D
Sbjct: 2460 EESEVTVGGLEPGRKYKMHLYGLHEGRR---------VGPVSTVGVTAPQED 2502
Score = 233 bits (594), Expect = 2e-60
Identities = 345/1590 (21%), Positives = 575/1590 (36%), Gaps = 279/1590 (17%)
Query: 900 GTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGE--HGQRLPIS 957
G + VP+ ++ + + V WTP V Y + IP R+P S
Sbjct: 742 GEDCGEEVPTIEGMRMHLLEETTVRTEWTPAPGPVDAYEIQFIPTTEGASPPFTARVPSS 801
Query: 958 RNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRW 1017
+ + + GL+PG Y V A+ P + TT +D P +L+ V T +T+ + W
Sbjct: 802 ASAYDQ-RGLAPGQEYQVTVRALRGTSWGLPASKTITTMIDGPQDLRVVAVTPTTLELGW 860
Query: 1018 TPPRAQITGYRLTVGLTRRGQPR-QYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESP 1076
P+A++ R V G R + V P L +L P EY V++ A +G S
Sbjct: 861 LRPQAEVD--RFVVSYVSAGNQRVRLEVPPEADGTLLTDLMPGVEYVVTVTAERGRAVSY 918
Query: 1077 KAT----------GVFTTLQPGSSIPPYNTEVTETTIV---------------------- 1104
A+ G+ T P T+ + ++
Sbjct: 919 PASVRANTGSSPLGLLGTTDEPPPSGPSTTQGAQAPLLQQRPQELGELRVLGRDETGRLR 978
Query: 1105 ITWTPAPR--IGFKLGVRPSQGGEAPREV-TSDSGSIVVSGLTPGVEYVYTIQVLRDGQE 1161
+ WT P F+L +R +G A EV D +V PG Y ++ + G +
Sbjct: 979 VVWTAQPDTFAYFQLRMRVPEGPGAHEEVLPGDVRQALVPPPPPGTPYELSLHGVPPGGK 1038
Query: 1162 RDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERS-------TTPDITGYRITTTPTN 1214
PI+ + + P G LTV+ S T P+ +
Sbjct: 1039 PSDPIIYQGIMDKDEEKPGKSSGPPRLGELTVTDRTSDSLLLRWTVPE-GEFDSFVIQYK 1097
Query: 1215 GQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPI---------SDTIIP 1265
+ G V Q S +L PG +Y +Y K P+ SD
Sbjct: 1098 DRDGQPQVVPVEGPQRSAVITSLDPGRKYKFVLYGFVGKKRHGPLVAEAKILPQSDPSPG 1157
Query: 1266 EVPQLTDLSFVDITDSSIGLRWTPLN---SSTIIGYRITVVAAGEGIPIFEDFVDSSVGY 1322
P L +L D T S+ L WT + ++ YR +G P V+
Sbjct: 1158 TPPHLGNLWVTDPTPDSLHLSWTVPEGQFDTFMVQYR-----DRDGRPQVVP-VEGPERS 1211
Query: 1323 YTVTGLEPGIDYDISVITLINGGESAPTTLTQQTA----VPPPT----------DLRFTN 1368
+ V+ L+P Y ++ + N P T TA PP +L T
Sbjct: 1212 FVVSSLDPDHKYRFTLFGIANKKRYGPLTADGTTAPERKEEPPRPEFLEQPLLGELTVTG 1271
Query: 1369 IGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLP------- 1421
+ PD++R++W +F+V+Y + + + ++ +N V + L P
Sbjct: 1272 VTPDSLRLSWTVAQG-PFDSFMVQYKDAQGQPQA--VPVAGDENEVTVPGLDPDRKYKMN 1328
Query: 1422 ----------GTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTG--------IDFSDITAN 1463
G E VV+ ++ E + TP + G ++P + + + +
Sbjct: 1329 LYGLRGRQRVGPESVVAKTAPQEDVDETP--SPTELGTEAPESPEEPLLGELTVTGSSPD 1386
Query: 1464 SFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEY-------- 1515
S ++ W P+ + + +++ GRPR RV + +T+ L PG +Y
Sbjct: 1387 SLSLFWTVPQGSFDSFTVQYKDR--DGRPRAVRVGGKESEVTVGGLEPGHKYKMHLYGLH 1444
Query: 1516 ------VVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYY 1569
VS V + ++ +S + +L V TP S+ +SW P +
Sbjct: 1445 EGQRVGPVSAVGVTAPQQEETPPATESPLEPRLGELTVTDVTPNSVGLSWTVPEGQFDSF 1504
Query: 1570 RITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAV-TGRGDSPAS----SKP 1624
+ Y + G Q V + T+ L+P Y + +Y + G+ P S + P
Sbjct: 1505 IVQYKDKDGQP--QVVPVAADQREVTVYNLEPERKYKMNMYGLHDGQRMGPLSVVIVTAP 1562
Query: 1625 ISINYRTEIDKP------SQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKT 1678
+ TE KP ++ VTD+ +S+ + W + V K+ G +
Sbjct: 1563 LPPAPATEASKPPLEPRLGELTVTDITPDSVGLSWTVPEGEFDSFVVQY--KDRDGQPQV 1620
Query: 1679 KTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTA--VTNIDRPKG-------L 1729
DQ E+TI L+P+ +Y ++ P+ A V D G L
Sbjct: 1621 VPVAADQREVTIPDLEPSRKYKFLLFGIQDGKRRSPVSVEAKTVARGDASPGAPPRLGEL 1680
Query: 1730 AFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEY 1789
TD DS++++W P+GQ + V + +DG ++ P +G E + + L G +Y
Sbjct: 1681 WVTDPTPDSLRLSWTVPEGQFDSFVVQFKD-KDG-PQVVPV-EGHERSVTVTPLDAGRKY 1737
Query: 1790 TVSVVALHDDMESQPLIGTQSTAI------------PAP---TDLKFTQVTPTSLSAQWT 1834
+ L PL +T P P +L+ T VT S+ WT
Sbjct: 1738 RFLLYGLLGKKRHGPLTADGTTEARSAMDDTGTKRPPKPRLGEELQVTTVTQNSVGLSWT 1797
Query: 1835 PPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRP 1894
P Q + V+ K++ G + + + V V GL A +Y++ +Y L P
Sbjct: 1798 VPEGQFDSFVVQY--KDRDGQPQVVPVEGSLREVSVPGLDPAHRYKLLLYGLHHGKRVGP 1855
Query: 1895 AQGVV-------TTLENVSPPRRA--------RVTDATETTITISWRTKTETITGFQVDA 1939
V T E +P A V +AT T+ +SW F++
Sbjct: 1856 ISAVAITAGREETETETTAPTPPAPEPHLGELTVEEATSHTLHLSWMVTEGEFDSFEIQY 1915
Query: 1940 VPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDA--------- 1990
+GQ + R I D T++GL+ Y + LY +D PV ++A
Sbjct: 1916 TDRDGQLQMVR-IGGDRNDITLSGLESDHRYLVTLYGFSDGKHVGPVHVEALTVPEEEKP 1974
Query: 1991 ---STAIDAP------SNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREV-VP 2040
TA P L TP+SL +SW P + ++++Y P+ V VP
Sbjct: 1975 SEPPTATPEPPIKPRLGELTVTDATPDSLSLSWTVPEGQFDHFLVQYRNGDGQPKAVRVP 2034
Query: 2041 RPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELPQLVTLPHPNLHGPE 2100
GV TI+GLEP +Y + + Q+ P+
Sbjct: 2035 GHEEGV---TISGLEPDHKYKMNLYGFHGGQRMGPV-----------------------S 2068
Query: 2101 ILDVPSTVQKTPFVTHPGYDTGNGIQLP-----GTSGQQP-SVGQQMIFEEHGFRRTTPP 2154
++ V + ++TP T P + + P +G P S+ + F T
Sbjct: 2069 VVGVTAAEEETPSPTEPSMEAPEPAEEPLLGELTVTGSSPDSLSLSWTVPQGRFDSFT-- 2126
Query: 2155 TTATPIRHRPRPYPPNV----GEEIQI---GHIPREDVDYHLYPHGPGL----------- 2196
++++ R P V GEE ++ G P HLY G
Sbjct: 2127 -----VQYKDRDGRPQVVRVGGEESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVSAVGVT 2181
Query: 2197 -----NPNASTGQEALSQTTI----------SWAPFQDTSEYIISCHPVGTDEEPLQFRV 2241
+P+A + L Q T+ SW + ++ + G D +P RV
Sbjct: 2182 APEEESPDAPLAKLRLGQMTVRDITSDSLSLSWTVPEGQFDHFLVQFKNG-DGQPKAVRV 2240
Query: 2242 PGTSTSATLTGLTRGATYNIIVEALKDQQR 2271
PG T++GL Y + + QR
Sbjct: 2241 PGHEDGVTISGLEPDHKYKMNLYGFHGGQR 2270
Score = 224 bits (570), Expect = 1e-57
Identities = 359/1680 (21%), Positives = 628/1680 (37%), Gaps = 290/1680 (17%)
Query: 822 VDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTEL--NLPETANSVTLSDLQPGVQYNIT 879
+++T++ W+ P+ Y I + P+ EG+S +P +A++ L PG +Y +T
Sbjct: 760 LEETTVRTEWTPAPGPVDAYEIQFIPTTEGASPPFTARVPSSASAYDQRGLAPGQEYQVT 819
Query: 880 IYAVEENQESTPVVIQQETTGTPRSDTVPS----PRDLQFVEVTDVKVTIMWTPPESAVT 935
+ A ++ + G P S T+ + P+DL+ V VT + + W P++ V
Sbjct: 820 VRA-----------LRGTSWGLPASKTITTMIDGPQDLRVVAVTPTTLELGWLRPQAEVD 868
Query: 936 GYRVDVIPVNLPGEHGQRLPISRNTFAE-VTGLSPGVTYYFKVFA-----------VSHG 983
+ V + G RL + +T L PGV Y V A V
Sbjct: 869 RFVVSYVSA---GNQRVRLEVPPEADGTLLTDLMPGVEYVVTVTAERGRAVSYPASVRAN 925
Query: 984 RESKPLTAQQTTKLDAPTNLQFVNETDSTVL----------------------VRWTPPR 1021
S PL TT P+ + +L V WT
Sbjct: 926 TGSSPLGLLGTTDEPPPSGPSTTQGAQAPLLQQRPQELGELRVLGRDETGRLRVVWTAQP 985
Query: 1022 AQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIK--GNQESPKA- 1078
++L + + + + V + + P + Y +SL + G P
Sbjct: 986 DTFAYFQLRMRVPEGPGAHEEVLPGDVRQALVPPPPPGTPYELSLHGVPPGGKPSDPIIY 1045
Query: 1079 TGVF--TTLQPG-SSIPPYNTEVTET-----TIVITWT-PAPRI-GFKLGVRPSQGGEAP 1128
G+ +PG SS PP E+T T ++++ WT P F + + G
Sbjct: 1046 QGIMDKDEEKPGKSSGPPRLGELTVTDRTSDSLLLRWTVPEGEFDSFVIQYKDRDGQPQV 1105
Query: 1129 REVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKV-VTPLSPPTNLHLEANPD 1187
V S V++ L PG +Y + + G++R P+V + + P S P+ P
Sbjct: 1106 VPVEGPQRSAVITSLDPGRKYKFVLYGF-VGKKRHGPLVAEAKILPQSDPSP---GTPPH 1161
Query: 1188 TGVLTVSWERSTTPDITGYRITTTPTNGQ-----------QGNSLEEVVHADQSSCTFDN 1236
G L W TPD ++ T GQ G V + S +
Sbjct: 1162 LGNL---WVTDPTPD--SLHLSWTVPEGQFDTFMVQYRDRDGRPQVVPVEGPERSFVVSS 1216
Query: 1237 LSPGLEYNVSVYTVKDDKESVPIS--DTIIP------------EVPQLTDLSFVDITDSS 1282
L P +Y +++ + + K P++ T P E P L +L+ +T S
Sbjct: 1217 LDPDHKYRFTLFGIANKKRYGPLTADGTTAPERKEEPPRPEFLEQPLLGELTVTGVTPDS 1276
Query: 1283 IGLRWTPLN---SSTIIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVI 1339
+ L WT S ++ Y+ + +P+ D ++ V TV GL+P Y +++
Sbjct: 1277 LRLSWTVAQGPFDSFMVQYK-DAQGQPQAVPVAGD--ENEV---TVPGLDPDRKYKMNLY 1330
Query: 1340 TLINGGESAPTTLTQQTA-------VPPPT----------------DLRFTNIGPDTMRV 1376
L P ++ +TA P PT +L T PD++ +
Sbjct: 1331 GLRGRQRVGPESVVAKTAPQEDVDETPSPTELGTEAPESPEEPLLGELTVTGSSPDSLSL 1390
Query: 1377 TWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYE-- 1434
W P +F V+Y + + + ++ V + L PG +Y + + ++E
Sbjct: 1391 FWTVPQG-SFDSFTVQYK--DRDGRPRAVRVGGKESEVTVGGLEPGHKYKMHLYGLHEGQ 1447
Query: 1435 -------------QHESTPLRGRQKTGLDSPTG-IDFSDITANSFTVHWIAPRATITGYR 1480
Q E TP ++ L+ G + +D+T NS + W P +
Sbjct: 1448 RVGPVSAVGVTAPQQEETP--PATESPLEPRLGELTVTDVTPNSVGLSWTVPEGQFDSFI 1505
Query: 1481 IRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVAL-NGREESPLLI------- 1532
+++ + G+P+ V + +T+ NL P +Y +++ L +G+ PL +
Sbjct: 1506 VQYKDK--DGQPQVVPVAADQREVTVYNLEPERKYKMNMYGLHDGQRMGPLSVVIVTAPL 1563
Query: 1533 -----GQQSTVSDVPR--DLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEF 1585
+ S PR +L V TP S+ +SW P + + Y + G Q
Sbjct: 1564 PPAPATEASKPPLEPRLGELTVTDITPDSVGLSWTVPEGEFDSFVVQYKDRDGQP--QVV 1621
Query: 1586 TVPGSKSTATISGLKPGVDYTITVYAV-TGRGDSPAS--SKPISINYRTEIDKP--SQMQ 1640
V + TI L+P Y ++ + G+ SP S +K ++ + P ++
Sbjct: 1622 PVAADQREVTIPDLEPSRKYKFLLFGIQDGKRRSPVSVEAKTVARGDASPGAPPRLGELW 1681
Query: 1641 VTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYV 1700
VTD +S+ + W + V K+GP + + +T+ L +Y
Sbjct: 1682 VTDPTPDSLRLSWTVPEGQFDSFVVQFKDKDGP---QVVPVEGHERSVTVTPLDAGRKYR 1738
Query: 1701 VSVYAQNPSGESQPLVQTAV---------TNIDRP------KGLAFTDVDVDSIKIAWES 1745
+Y PL T RP + L T V +S+ ++W
Sbjct: 1739 FLLYGLLGKKRHGPLTADGTTEARSAMDDTGTKRPPKPRLGEELQVTTVTQNSVGLSWTV 1798
Query: 1746 PQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPL 1805
P+GQ + V Y DG ++ P +G + GL P Y + + LH P+
Sbjct: 1799 PEGQFDSFVVQYKD-RDGQPQVVPV-EGSLREVSVPGLDPAHRYKLLLYGLHHGKRVGPI 1856
Query: 1806 IGTQSTA--------IPAPT---------DLKFTQVTPTSLSAQWTPPNVQLTGYRVRVT 1848
TA APT +L + T +L W + + ++ T
Sbjct: 1857 SAVAITAGREETETETTAPTPPAPEPHLGELTVEEATSHTLHLSWMVTEGEFDSFEIQYT 1916
Query: 1849 PKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKD----------TLT----SRP 1894
++ G ++ + + D + + +SGL +Y V++Y D LT +P
Sbjct: 1917 --DRDGQLQMVRIGGDRNDITLSGLESDHRYLVTLYGFSDGKHVGPVHVEALTVPEEEKP 1974
Query: 1895 AQGVVTTLENVSPPR--RARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTI 1952
++ T E PR VTDAT ++++SW F V +GQ R +
Sbjct: 1975 SEPPTATPEPPIKPRLGELTVTDATPDSLSLSWTVPEGQFDHFLVQYRNGDGQPKAVR-V 2033
Query: 1953 KPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTA------------IDAP--- 1997
TI+GL+P YK+ LY + R PV + TA ++AP
Sbjct: 2034 PGHEEGVTISGLEPDHKYKMNLYGFHGGQRMGPVSVVGVTAAEEETPSPTEPSMEAPEPA 2093
Query: 1998 -----SNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATIT 2052
L ++P+SL +SW P+ R + ++Y+ P+ V R +E T+
Sbjct: 2094 EEPLLGELTVTGSSPDSLSLSWTVPQGRFDSFTVQYKDRDGRPQ--VVRVGGEESEVTVG 2151
Query: 2053 GLEPGTEYTIYVIALKNNQKSEPL--IGRKKTDELPQLVTLPHPNLHGPEILDVPSTVQK 2110
GLEPG +Y +++ L ++ P+ +G +E L L + D+ S
Sbjct: 2152 GLEPGRKYKMHLYGLHEGRRVGPVSAVGVTAPEEESPDAPLAKLRLGQMTVRDITSDSLS 2211
Query: 2111 TPFVTHPG--------YDTGNG----IQLPG------TSGQQPSVGQQM-IFEEHGFRRT 2151
+ G + G+G +++PG SG +P +M ++ HG +R
Sbjct: 2212 LSWTVPEGQFDHFLVQFKNGDGQPKAVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQRV 2271
Query: 2152 TPPTTATPIRHRPRPYPPNVGEEIQIGHIPREDVDYHLYPHGPGLNPNASTGQEALSQTT 2211
P + P EE+ + + P L +T ++LS
Sbjct: 2272 GPVSAVGLT-------APGKDEEMAPASTEPPTPEPPIKPRLEELTVTDAT-PDSLS--- 2320
Query: 2212 ISWAPFQDTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQR 2271
+SW + ++ + + G D +P RVPG T++GL Y + + QR
Sbjct: 2321 LSWTVPEGQFDHFLVQYKNG-DGQPKATRVPGHEDRVTISGLEPDNKYKMNLYGFHGGQR 2379
Score = 206 bits (523), Expect = 3e-52
Identities = 291/1263 (23%), Positives = 464/1263 (36%), Gaps = 195/1263 (15%)
Query: 1192 TVSWERSTTPD-ITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDN--LSPGLEYNVSVY 1248
TV E + P + Y I PT +G S S+ +D L+PG EY V+V
Sbjct: 764 TVRTEWTPAPGPVDAYEIQFIPTT--EGASPPFTARVPSSASAYDQRGLAPGQEYQVTVR 821
Query: 1249 TVKDDKESVPISDTIIPEVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGEG 1308
++ +P S TI + DL V +T +++ L W + + + ++ V+AG
Sbjct: 822 ALRGTSWGLPASKTITTMIDGPQDLRVVAVTPTTLELGWLRPQAE-VDRFVVSYVSAGNQ 880
Query: 1309 IPIFEDFVDSSVGYYTVTGLEPGIDYDISVIT------------LINGGESAPTTLTQQT 1356
E V +T L PG++Y ++V N G S+P L T
Sbjct: 881 RVRLE--VPPEADGTLLTDLMPGVEYVVTVTAERGRAVSYPASVRANTG-SSPLGLLGTT 937
Query: 1357 AVPPPTDLRFTN-------------------IGPDT---MRVTWAPPPSIDLTNFLVRY- 1393
PPP+ T +G D +RV W P F +R
Sbjct: 938 DEPPPSGPSTTQGAQAPLLQQRPQELGELRVLGRDETGRLRVVWTAQPDT-FAYFQLRMR 996
Query: 1394 ---SPVKNEE----DVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHE-STPL---- 1441
P +EE DV + + P PGT Y +S+ V + S P+
Sbjct: 997 VPEGPGAHEEVLPGDVRQALVPPPP---------PGTPYELSLHGVPPGGKPSDPIIYQG 1047
Query: 1442 ---RGRQKTGLDSPTG----IDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPRE 1494
+ +K G S + +D T++S + W P + I++ G+P+
Sbjct: 1048 IMDKDEEKPGKSSGPPRLGELTVTDRTSDSLLLRWTVPEGEFDSFVIQYKDR--DGQPQV 1105
Query: 1495 DRVPHSRNSITLTNLTPGTEYVVSIVALNGRE-------ESPLLIGQQSTVSDVPR--DL 1545
V + S +T+L PG +Y + G++ E+ +L + P +L
Sbjct: 1106 VPVEGPQRSAVITSLDPGRKYKFVLYGFVGKKRHGPLVAEAKILPQSDPSPGTPPHLGNL 1165
Query: 1546 EVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDY 1605
V TP SL +SW P + + Y + G V V G + + +S L P Y
Sbjct: 1166 WVTDPTPDSLHLSWTVPEGQFDTFMVQYRDRDGRPQV--VPVEGPERSFVVSSLDPDHKY 1223
Query: 1606 TITVYAVTGRGD-SPASSKPISINYRTE-------IDKP--SQMQVTDVQDNSISVKWLP 1655
T++ + + P ++ + R E +++P ++ VT V +S+ + W
Sbjct: 1224 RFTLFGIANKKRYGPLTADGTTAPERKEEPPRPEFLEQPLLGELTVTGVTPDSLRLSWTV 1283
Query: 1656 SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYA----QNPSGE 1711
+ P + V G P AG D+ E+T+ GL P +Y +++Y Q E
Sbjct: 1284 AQGPFDSFMVQYKDAQGQ-PQAVPVAG-DENEVTVPGLDPDRKYKMNLYGLRGRQRVGPE 1341
Query: 1712 SQPLVQTAVTNIDRPKG-------------------LAFTDVDVDSIKIAWESPQGQVSR 1752
S ++D L T DS+ + W PQG
Sbjct: 1342 SVVAKTAPQEDVDETPSPTELGTEAPESPEEPLLGELTVTGSSPDSLSLFWTVPQGSFDS 1401
Query: 1753 YRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIG----- 1807
+ V Y DG G+E + GL PG +Y + + LH+ P+
Sbjct: 1402 FTVQYKD-RDGRPRAVRV-GGKESEVTVGGLEPGHKYKMHLYGLHEGQRVGPVSAVGVTA 1459
Query: 1808 ---------TQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKE 1858
T+S P +L T VTP S+ WT P Q + V+ K+K G +
Sbjct: 1460 PQQEETPPATESPLEPRLGELTVTDVTPNSVGLSWTVPEGQFDSFIVQY--KDKDGQPQV 1517
Query: 1859 INLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTL--------ENVSPPRR 1910
+ +A D V V L KY++++Y L D P V+ T E PP
Sbjct: 1518 VPVAADQREVTVYNLEPERKYKMNMYGLHDGQRMGPLSVVIVTAPLPPAPATEASKPPLE 1577
Query: 1911 AR-----VTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQ 1965
R VTD T ++ +SW F V +GQ + + D R TI L+
Sbjct: 1578 PRLGELTVTDITPDSVGLSWTVPEGEFDSFVVQYKDRDGQPQVV-PVAADQREVTIPDLE 1636
Query: 1966 PGTDYKIYLYTLNDNARSSPVVIDASTAI------DAPSNLRFL---ATTPNSLLVSWQP 2016
P YK L+ + D R SPV ++A T AP L L TP+SL +SW
Sbjct: 1637 PSRKYKFLLFGIQDGKRRSPVSVEAKTVARGDASPGAPPRLGELWVTDPTPDSLRLSWTV 1696
Query: 2017 PRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPL 2076
P + ++++++ P +VVP T+T L+ G +Y + L ++ PL
Sbjct: 1697 PEGQFDSFVVQFKDKDGP--QVVP-VEGHERSVTVTPLDAGRKYRFLLYGLLGKKRHGPL 1753
Query: 2077 IGRKKTD---ELPQLVTLPHPNLHGPEILDVPSTVQKT---PFVTHPGYDTGNGIQLPGT 2130
T+ + T P E L V + Q + + G +Q
Sbjct: 1754 TADGTTEARSAMDDTGTKRPPKPRLGEELQVTTVTQNSVGLSWTVPEGQFDSFVVQYKDR 1813
Query: 2131 SGQQPSVGQQMIFEEHGFRRTTPPTTATPIRHRPRPYPPNVGEE--------IQIGHIPR 2182
GQ Q++ E R + P R++ Y + G+ I G
Sbjct: 1814 DGQ-----PQVVPVEGSLREVSVPGLDPAHRYKLLLYGLHHGKRVGPISAVAITAGREET 1868
Query: 2183 EDVDYHLYPHGPGLNPNASTGQEALSQTT-ISWAPFQDTSEYIISCHPVGTDEEPLQFRV 2241
E P P + T +EA S T +SW + + D + R+
Sbjct: 1869 ETETTAPTPPAPEPHLGELTVEEATSHTLHLSWMVTEGEFD-SFEIQYTDRDGQLQMVRI 1927
Query: 2242 PGTSTSATLTGLTRGATYNIIVEALKDQQRHKVREEVVTVGNSVNEGLNQPTDDSCFDPY 2301
G TL+GL Y + + D + VG E L P ++ +P
Sbjct: 1928 GGDRNDITLSGLESDHRYLVTLYGFSDGKH---------VGPVHVEALTVPEEEKPSEPP 1978
Query: 2302 TVS 2304
T +
Sbjct: 1979 TAT 1981
Score = 103 bits (258), Expect = 2e-21
Identities = 103/429 (24%), Positives = 166/429 (38%), Gaps = 62/429 (14%)
Query: 1704 YAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDG 1763
YA GE P ++ G+ ++ +++ W G V Y + + +G
Sbjct: 740 YAGEDCGEEVPTIE----------GMRMHLLEETTVRTEWTPAPGPVDAYEIQFIPTTEG 789
Query: 1764 IHELFPAPDGEEDTA-ELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFT 1822
F A +A + +GL PG EY V+V AL P T +T I P DL+
Sbjct: 790 ASPPFTARVPSSASAYDQRGLAPGQEYQVTVRALRGTSWGLPASKTITTMIDGPQDLRVV 849
Query: 1823 QVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVS 1882
VTPT+L W P ++ R V+ + + P++ +++ LM +Y V+
Sbjct: 850 AVTPTTLELGWLRPQAEVD--RFVVSYVSAGNQRVRLEVPPEADGTLLTDLMPGVEYVVT 907
Query: 1883 VYALKDTLTSRPAQ----------GVVTTLENVSPP--------------------RRAR 1912
V A + S PA G++ T + P R
Sbjct: 908 VTAERGRAVSYPASVRANTGSSPLGLLGTTDEPPPSGPSTTQGAQAPLLQQRPQELGELR 967
Query: 1913 VTDATET-TITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYK 1971
V ET + + W + +T FQ+ G + + DVR + PGT Y+
Sbjct: 968 VLGRDETGRLRVVWTAQPDTFAYFQLRMRVPEGPGAHEEVLPGDVRQALVPPPPPGTPYE 1027
Query: 1972 IYLYTLNDNAR-SSPVVIDASTAID--------APSNLRFLAT---TPNSLLVSWQPPRA 2019
+ L+ + + S P++ D P L L T +SLL+ W P
Sbjct: 1028 LSLHGVPPGGKPSDPIIYQGIMDKDEEKPGKSSGPPRLGELTVTDRTSDSLLLRWTVPEG 1087
Query: 2020 RITGYIIKY-EKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIG 2078
++I+Y ++ G P +VVP P A IT L+PG +Y + ++ PL+
Sbjct: 1088 EFDSFVIQYKDRDGQP--QVVPVEGP-QRSAVITSLDPGRKYKFVLYGFVGKKRHGPLVA 1144
Query: 2079 RKKTDELPQ 2087
K LPQ
Sbjct: 1145 EAKI--LPQ 1151
Score = 89.0 bits (219), Expect = 5e-17
Identities = 93/400 (23%), Positives = 144/400 (36%), Gaps = 67/400 (16%)
Query: 1918 ETTITISWRTKTETITGFQVDAVPAN--GQTPIQRTIKPDVRSYTITGLQPGTDYKIYLY 1975
ETT+ W + +++ +P P + +Y GL PG +Y++ +
Sbjct: 762 ETTVRTEWTPAPGPVDAYEIQFIPTTEGASPPFTARVPSSASAYDQRGLAPGQEYQVTVR 821
Query: 1976 TLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPP 2035
L + P +T ID P +LR +A TP +L + W P+A + +++ Y G+
Sbjct: 822 ALRGTSWGLPASKTITTMIDGPQDLRVVAVTPTTLELGWLRPQAEVDRFVVSYVSAGN-- 879
Query: 2036 REVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELPQLVTLPHPN 2095
+ V P +T L PG EY + V A + S P R T P
Sbjct: 880 QRVRLEVPPEADGTLLTDLMPGVEYVVTVTAERGRAVSYPASVRANTGSSP--------- 930
Query: 2096 LHGPEILDVPSTVQKTPFVTHPGYDTGNGIQLPGTSGQQPSVGQQMIF--EEHGFRR--- 2150
L + T + P G T G Q P + +G+ + +E G R
Sbjct: 931 ------LGLLGTTDEPP---PSGPSTTQGAQAPLLQQRPQELGELRVLGRDETGRLRVVW 981
Query: 2151 TTPPTTATPIRHRPR-PYPPNVGEEIQIGHI-------PREDVDYHLYPHG--PG----- 2195
T P T + R R P P EE+ G + P Y L HG PG
Sbjct: 982 TAQPDTFAYFQLRMRVPEGPGAHEEVLPGDVRQALVPPPPPGTPYELSLHGVPPGGKPSD 1041
Query: 2196 ------------LNPNASTGQEALSQTTIS----------W-APFQDTSEYIISCHPVGT 2232
P S+G L + T++ W P + ++I
Sbjct: 1042 PIIYQGIMDKDEEKPGKSSGPPRLGELTVTDRTSDSLLLRWTVPEGEFDSFVIQYK--DR 1099
Query: 2233 DEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRH 2272
D +P V G SA +T L G Y ++ ++RH
Sbjct: 1100 DGQPQVVPVEGPQRSAVITSLDPGRKYKFVLYGFVGKKRH 1139
>gi|157384973 tenascin R [Homo sapiens]
Length = 1358
Score = 329 bits (844), Expect = 2e-89
Identities = 237/807 (29%), Positives = 374/807 (46%), Gaps = 32/807 (3%)
Query: 1272 DLSFVDITDSSIGLRWTPLNSST--IIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLE 1329
DL I+D SI L W + T +I Y+ T + + + V T+T LE
Sbjct: 331 DLRVAGISDRSIELEWDGPMAVTEYVISYQPTALGGLQ----LQQRVPGDWSGVTITELE 386
Query: 1330 PGIDYDISVITLINGGESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNF 1389
PG+ Y+ISV +I+ S P T T + P L+F I T+ V W P S +
Sbjct: 387 PGLTYNISVYAVISNILSLPITAKVATHLSTPQGLQFKTITETTVEVQWEPF-SFSFDGW 445
Query: 1390 LVRYSPVKNEEDVAELSISPSD-NAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTG 1448
+ + P NE V ++ PSD + T L PG EY+V+V ++ EQ S P T
Sbjct: 446 EISFIPKNNEGGV--IAQVPSDVTSFNQTGLKPGEEYIVNVVALKEQARSPPTSASVSTV 503
Query: 1449 LDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTN 1508
+D PT I D++ V WI PRA + +++ G R+ + ++
Sbjct: 504 IDGPTQILVRDVSDTVAFVEWIPPRAKVDFILLKYGLVGGEGGRTTFRLQPPLSQYSVQA 563
Query: 1509 LTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRY 1568
L PG+ Y VS+ A+ G ES Q +T D P++L V + T TSL + WD V+
Sbjct: 564 LRPGSRYEVSVSAVRGTNESDSATTQFTTEIDAPKNLRVGSRTATSLDLEWDNSEAEVQE 623
Query: 1569 YRITYGETGGNSPVQEFTVP---GSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPI 1625
Y++ Y G E VP G + AT++ L PG +Y + + AV + S P
Sbjct: 624 YKVVYSTLAGEQ-YHEVLVPRGIGPTTRATLTDLVPGTEYGVGISAVM----NSQQSVPA 678
Query: 1626 SINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQ 1685
++N RTE+D P + VT + SIS+ W +S P+ YR+T TP +G T D+
Sbjct: 679 TMNARTELDSPRDLMVTASSETSISLIWTKASGPIDHYRITFTPSSGIA--SEVTVPKDR 736
Query: 1686 TEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWES 1745
T T+ L+P EY++SV A+ +S A T L F+ V S+ I W
Sbjct: 737 TSYTLTDLEPGAEYIISVTAERGRQQSLESTVDAFTGFRPISHLHFSHVTSSSVNITWSD 796
Query: 1746 PQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPL 1805
P R + YS ++ + + D + A L GL+P +EY V++VA+H + S+P+
Sbjct: 797 PSPPADRLILNYSPRDEEEEMMEVSLDATKRHAVLMGLQPATEYIVNLVAVHGTVTSEPI 856
Query: 1806 IGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDS 1865
+G+ +T I P D+ + VT S+ W+PP YRV P + G + +
Sbjct: 857 VGSITTGIDPPKDITISNVTKDSVMVSWSPPVASFDYYRVSYRPTQ-VGRLDSSVVPNTV 915
Query: 1866 SSVVVSGLMVATKYEVSVYALKDTLTS-RPAQGVVTTLENVSPPRRARVTDATETTITIS 1924
+ ++ L AT+YE+S+ +++ S R V T ++N P T+ T T +
Sbjct: 916 TEFTITRLNPATEYEISLNSVRGREESERICTLVHTAMDN---PVDLIATNITPTEALLQ 972
Query: 1925 WRTKTETITGFQV--DAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNAR 1982
W+ + + + G+T + + + R + L P T Y +Y N
Sbjct: 973 WKAPVGEVENYVIVLTHFAVAGETILVDGVSEEFR---LVDLLPSTHYTATMYATNGPLT 1029
Query: 1983 SSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRP 2042
S + + ST +D P+NL T S L+SWQPPRA I Y++ Y+ +E++
Sbjct: 1030 SGTISTNFSTLLDPPANLTASEVTRQSALISWQPPRAEIENYVLTYKSTDGSRKELIVDA 1089
Query: 2043 RPGVTEATITGLEPGTEYTIYVIALKN 2069
T + GL T+YT+ + A ++
Sbjct: 1090 ED--TWIRLEGLLENTDYTVLLQAAQD 1114
Score = 315 bits (807), Expect = 4e-85
Identities = 243/828 (29%), Positives = 372/828 (44%), Gaps = 30/828 (3%)
Query: 902 PRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTF 961
P V P DL+ ++D + + W P AVT Y + P L G Q+ +
Sbjct: 321 PDCSAVAPPEDLRVAGISDRSIELEWDGP-MAVTEYVISYQPTALGGLQLQQRVPGDWSG 379
Query: 962 AEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPR 1021
+T L PG+TY V+AV S P+TA+ T L P LQF T++TV V+W P
Sbjct: 380 VTITELEPGLTYNISVYAVISNILSLPITAKVATHLSTPQGLQFKTITETTVEVQWEPFS 439
Query: 1022 AQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGV 1081
G+ ++ V V+ + L+P EY V++VA+K SP +
Sbjct: 440 FSFDGWEISFIPKNNEGGVIAQVPSDVTSFNQTGLKPGEEYIVNVVALKEQARSPPTSAS 499
Query: 1082 FTTLQPGSSIPPYNTEVTETTIVITWTPAPR-----IGFKLGVRPSQGGEAPREVTSDSG 1136
+T+ G + +V++T + W P PR I K G+ +GG +
Sbjct: 500 VSTVIDGPT-QILVRDVSDTVAFVEWIP-PRAKVDFILLKYGLVGGEGGRTTFRLQPPLS 557
Query: 1137 SIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWE 1196
V L PG Y ++ +R E D+ + T + P NL + + T L + W+
Sbjct: 558 QYSVQALRPGSRYEVSVSAVRGTNESDS-ATTQFTTEIDAPKNLRVGSRTATS-LDLEWD 615
Query: 1197 RSTTPDITGYRITTTPTNGQQGNS-LEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKE 1255
S ++ Y++ + G+Q + L + T +L PG EY V + V + ++
Sbjct: 616 NSEA-EVQEYKVVYSTLAGEQYHEVLVPRGIGPTTRATLTDLVPGTEYGVGISAVMNSQQ 674
Query: 1256 SVPISDTIIPEVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIFEDF 1315
SVP + E+ DL +++SI L WT S I YRIT + GI E
Sbjct: 675 SVPATMNARTELDSPRDLMVTASSETSISLIWTKA-SGPIDHYRITFTPS-SGI-ASEVT 731
Query: 1316 VDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAVPPPTDLRFTNIGPDTMR 1375
V YT+T LEPG +Y ISV +S +T+ T P + L F+++ ++
Sbjct: 732 VPKDRTSYTLTDLEPGAEYIISVTAERGRQQSLESTVDAFTGFRPISHLHFSHVTSSSVN 791
Query: 1376 VTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQ 1435
+TW+ PS ++ YSP EE++ E+S+ + VL L P TEY+V++ +V+
Sbjct: 792 ITWS-DPSPPADRLILNYSPRDEEEEMMEVSLDATKRHAVLMGLQPATEYIVNLVAVHGT 850
Query: 1436 HESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPRED 1495
S P+ G TG+D P I S++T +S V W P A+ YR+ + P GR
Sbjct: 851 VTSEPIVGSITTGIDPPKDITISNVTKDSVMVSWSPPVASFDYYRVSYRPTQV-GRLDSS 909
Query: 1496 RVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSL 1555
VP++ T+T L P TEY +S+ ++ GREES + T D P DL TPT
Sbjct: 910 VVPNTVTEFTITRLNPATEYEISLNSVRGREESERICTLVHTAMDNPVDLIATNITPTEA 969
Query: 1556 LISWDAPAVTVRYYRI--TYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVT 1613
L+ W AP V Y I T+ G + V G + L P YT T+YA
Sbjct: 970 LLQWKAPVGEVENYVIVLTHFAVAG----ETILVDGVSEEFRLVDLLPSTHYTATMYATN 1025
Query: 1614 GRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGP 1673
G P +S IS N+ T +D P+ + ++V S + W P + + Y T K+
Sbjct: 1026 G----PLTSGTISTNFSTLLDPPANLTASEVTRQSALISWQPPRAEIENY--VLTYKSTD 1079
Query: 1674 GPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVT 1721
G K + T + +EGL +Y V + A + S + TA T
Sbjct: 1080 GSRKELIVDAEDTWIRLEGLLENTDYTVLLQAAQDTTWSS-ITSTAFT 1126
Score = 308 bits (788), Expect = 6e-83
Identities = 243/852 (28%), Positives = 391/852 (45%), Gaps = 56/852 (6%)
Query: 783 GRKYIVNVYQISEDGEQSLILSTSQTTAPD----APP-DPTVDQVDDTSIVVRWSRPQAP 837
G++ +N E+ L + PD APP D V + D SI + W P A
Sbjct: 293 GQRQCLNACSGRGQCEEGLCVCEEGYQGPDCSAVAPPEDLRVAGISDRSIELEWDGPMA- 351
Query: 838 ITGYRIVYSPSVEGS-STELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQ 896
+T Y I Y P+ G + +P + VT+++L+PG+ YNI++YAV N S P+ +
Sbjct: 352 VTEYVISYQPTALGGLQLQQRVPGDWSGVTITELEPGLTYNISVYAVISNILSLPITAKV 411
Query: 897 ETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPI 956
T + +P+ LQF +T+ V + W P + G+ + IP N G ++P
Sbjct: 412 AT-------HLSTPQGLQFKTITETTVEVQWEPFSFSFDGWEISFIPKNNEGGVIAQVPS 464
Query: 957 SRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVR 1016
+F + TGL PG Y V A+ S P +A +T +D PT + + +D+ V
Sbjct: 465 DVTSFNQ-TGLKPGEEYIVNVVALKEQARSPPTSASVSTVIDGPTQILVRDVSDTVAFVE 523
Query: 1017 WTPPRAQITGYRLTVGLT-RRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQES 1075
W PPRA++ L GL G + + P +S+Y ++ L+P S Y VS+ A++G ES
Sbjct: 524 WIPPRAKVDFILLKYGLVGGEGGRTTFRLQPPLSQYSVQALRPGSRYEVSVSAVRGTNES 583
Query: 1076 PKATGVFTTLQPGSSIPPYNTEV---TETTIVITW--TPAPRIGFKLGVRPSQGGEAPRE 1130
AT FTT P N V T T++ + W + A +K+ V + GE E
Sbjct: 584 DSATTQFTT----EIDAPKNLRVGSRTATSLDLEWDNSEAEVQEYKV-VYSTLAGEQYHE 638
Query: 1131 VTSDSG-----SIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEAN 1185
V G ++ L PG EY I + + Q+ P T L P +L + A+
Sbjct: 639 VLVPRGIGPTTRATLTDLVPGTEYGVGISAVMNSQQ-SVPATMNARTELDSPRDLMVTAS 697
Query: 1186 PDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNV 1245
+T + ++ W +++ P I YRIT TP++ G + E V D++S T +L PG EY +
Sbjct: 698 SETSI-SLIWTKASGP-IDHYRITFTPSS---GIASEVTVPKDRTSYTLTDLEPGAEYII 752
Query: 1246 SVYTVKDDKESVPISDTIIPEVPQLTDLSFVDITDSSIGLRW---TPLNSSTIIGYRITV 1302
SV + ++S+ + ++ L F +T SS+ + W +P I+ Y
Sbjct: 753 SVTAERGRQQSLESTVDAFTGFRPISHLHFSHVTSSSVNITWSDPSPPADRLILNYS--- 809
Query: 1303 VAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAVPPPT 1362
E + E +D++ + + GL+P +Y ++++ + S P + T + PP
Sbjct: 810 -PRDEEEEMMEVSLDATKRHAVLMGLQPATEYIVNLVAVHGTVTSEPIVGSITTGIDPPK 868
Query: 1363 DLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAV---VLTNL 1419
D+ +N+ D++ V+W+PP + + V Y P + V L S N V +T L
Sbjct: 869 DITISNVTKDSVMVSWSPPVA-SFDYYRVSYRPTQ----VGRLDSSVVPNTVTEFTITRL 923
Query: 1420 LPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGY 1479
P TEY +S++SV + ES + T +D+P + ++IT + W AP + Y
Sbjct: 924 NPATEYEISLNSVRGREESERICTLVHTAMDNPVDLIATNITPTEALLQWKAPVGEVENY 983
Query: 1480 RIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVS 1539
I HF+ V L +L P T Y ++ A NG S + ST+
Sbjct: 984 VI--VLTHFAVAGETILVDGVSEEFRLVDLLPSTHYTATMYATNGPLTSGTISTNFSTLL 1041
Query: 1540 DVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGL 1599
D P +L T S LISW P + Y +TY T G+ +E V + + GL
Sbjct: 1042 DPPANLTASEVTRQSALISWQPPRAEIENYVLTYKSTDGSR--KELIVDAEDTWIRLEGL 1099
Query: 1600 KPGVDYTITVYA 1611
DYT+ + A
Sbjct: 1100 LENTDYTVLLQA 1111
Score = 265 bits (676), Expect = 5e-70
Identities = 216/817 (26%), Positives = 357/817 (43%), Gaps = 27/817 (3%)
Query: 1098 VTETTIVITWT-PAPRIGFKLGVRPSQGG--EAPREVTSDSGSIVVSGLTPGVEYVYTIQ 1154
+++ +I + W P + + +P+ G + + V D + ++ L PG+ Y ++
Sbjct: 337 ISDRSIELEWDGPMAVTEYVISYQPTALGGLQLQQRVPGDWSGVTITELEPGLTYNISVY 396
Query: 1155 VLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTN 1214
+ PI KV T LS P L + +T V V WE + G+ I+ P N
Sbjct: 397 AVISNI-LSLPITAKVATHLSTPQGLQFKTITETTV-EVQWEPFSF-SFDGWEISFIPKN 453
Query: 1215 GQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPEVPQLTDLS 1274
+ G + V +D +S L PG EY V+V +K+ S P S ++ + T +
Sbjct: 454 NEGGVIAQ--VPSDVTSFNQTGLKPGEEYIVNVVALKEQARSPPTSASVSTVIDGPTQIL 511
Query: 1275 FVDITDSSIGLRWTPLNSST-IIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGID 1333
D++D+ + W P + I + +V G F + + Y+V L PG
Sbjct: 512 VRDVSDTVAFVEWIPPRAKVDFILLKYGLVGGEGGRTTFR--LQPPLSQYSVQALRPGSR 569
Query: 1334 YDISVITLINGGESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRY 1393
Y++SV + ES T T + P +LR + ++ + W + ++ + V Y
Sbjct: 570 YEVSVSAVRGTNESDSATTQFTTEIDAPKNLRVGSRTATSLDLEWDNSEA-EVQEYKVVY 628
Query: 1394 SPVKNE---EDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLD 1450
S + E E + I P+ A LT+L+PGTEY V +S+V +S P +T LD
Sbjct: 629 STLAGEQYHEVLVPRGIGPTTRAT-LTDLVPGTEYGVGISAVMNSQQSVPATMNARTELD 687
Query: 1451 SPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLT 1510
SP + + + S ++ W I YRI P SG E VP R S TLT+L
Sbjct: 688 SPRDLMVTASSETSISLIWTKASGPIDHYRITFTPS--SGIASEVTVPKDRTSYTLTDLE 745
Query: 1511 PGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYR 1570
PG EY++S+ A GR++S T L T +S+ I+W P+
Sbjct: 746 PGAEYIISVTAERGRQQSLESTVDAFTGFRPISHLHFSHVTSSSVNITWSDPSPPADRLI 805
Query: 1571 ITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYR 1630
+ Y + E ++ +K A + GL+P +Y + + AV G +S+PI +
Sbjct: 806 LNYSPRDEEEEMMEVSLDATKRHAVLMGLQPATEYIVNLVAVHGT----VTSEPIVGSIT 861
Query: 1631 TEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTI 1690
T ID P + +++V +S+ V W P + YRV+ P G + TE TI
Sbjct: 862 TGIDPPKDITISNVTKDSVMVSWSPPVASFDYYRVSYRPTQ-VGRLDSSVVPNTVTEFTI 920
Query: 1691 EGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQV 1750
L P EY +S+ + ES+ + T +D P L T++ + W++P G+V
Sbjct: 921 TRLNPATEYEISLNSVRGREESERICTLVHTAMDNPVDLIATNITPTEALLQWKAPVGEV 980
Query: 1751 SRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQS 1810
Y + + + DG + L L P + YT ++ A + + S + S
Sbjct: 981 ENYVIVLTHFAVAGETILV--DGVSEEFRLVDLLPSTHYTATMYATNGPLTSGTISTNFS 1038
Query: 1811 TAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVV 1870
T + P +L ++VT S W PP ++ Y + T K G KE+ + + + + +
Sbjct: 1039 TLLDPPANLTASEVTRQSALISWQPPRAEIENYVL--TYKSTDGSRKELIVDAEDTWIRL 1096
Query: 1871 SGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSP 1907
GL+ T Y V + A +DT S TT V P
Sbjct: 1097 EGLLENTDYTVLLQAAQDTTWSSITSTAFTTGGRVFP 1133
Score = 243 bits (620), Expect = 2e-63
Identities = 217/855 (25%), Positives = 356/855 (41%), Gaps = 53/855 (6%)
Query: 1442 RGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSR 1501
+G + + P + + I+ S + W P A +T Y I + P G + RVP
Sbjct: 319 QGPDCSAVAPPEDLRVAGISDRSIELEWDGPMA-VTEYVISYQPTALGGLQLQQRVPGDW 377
Query: 1502 NSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDA 1561
+ +T+T L PG Y +S+ A+ S + + +T P+ L+ T T++ + W+
Sbjct: 378 SGVTITELEPGLTYNISVYAVISNILSLPITAKVATHLSTPQGLQFKTITETTVEVQWEP 437
Query: 1562 PAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPAS 1621
+ + + I++ V VP ++ +GLKPG +Y + V A+ + SP +
Sbjct: 438 FSFSFDGWEISFIPKNNEGGVIA-QVPSDVTSFNQTGLKPGEEYIVNVVALKEQARSPPT 496
Query: 1622 SKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTA 1681
S +S T ID P+Q+ V DV D V+W+P + V + G G T
Sbjct: 497 SASVS----TVIDGPTQILVRDVSDTVAFVEWIPPRAKVDFILLKYGLVGGEGGRTTFRL 552
Query: 1682 GPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKI 1741
P ++ +++ L+P Y VSV A + ES T ID PK L S+ +
Sbjct: 553 QPPLSQYSVQALRPGSRYEVSVSAVRGTNESDSATTQFTTEIDAPKNLRVGSRTATSLDL 612
Query: 1742 AWESPQGQVSRYRVTYSS-PEDGIHE-LFPAPDGEEDTAELQGLRPGSEYTVSVVALHDD 1799
W++ + +V Y+V YS+ + HE L P G A L L PG+EY V + A+ +
Sbjct: 613 EWDNSEAEVQEYKVVYSTLAGEQYHEVLVPRGIGPTTRATLTDLVPGTEYGVGISAVMNS 672
Query: 1800 MESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEI 1859
+S P T + +P DL T + TS+S WT + + YR+ TP +G E+
Sbjct: 673 QQSVPATMNARTELDSPRDLMVTASSETSISLIWTKASGPIDHYRITFTPS--SGIASEV 730
Query: 1860 NLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATET 1919
+ D +S ++ L +Y +SV A + S + V P + T +
Sbjct: 731 TVPKDRTSYTLTDLEPGAEYIISVTAERGRQQS--LESTVDAFTGFRPISHLHFSHVTSS 788
Query: 1920 TITISWRTKTETITGFQVDAVPANGQTPIQR-TIKPDVRSYTITGLQPGTDYKIYLYTLN 1978
++ I+W + ++ P + + + ++ R + GLQP T+Y + L ++
Sbjct: 789 SVNITWSDPSPPADRLILNYSPRDEEEEMMEVSLDATKRHAVLMGLQPATEYIVNLVAVH 848
Query: 1979 DNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYE--KPGSPPR 2036
S P+V +T ID P ++ T +S++VSW PP A Y + Y + G
Sbjct: 849 GTVTSEPIVGSITTGIDPPKDITISNVTKDSVMVSWSPPVASFDYYRVSYRPTQVGRLDS 908
Query: 2037 EVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELPQLVTLPHPNL 2096
VVP VTE TIT L P TEY I + +++ ++SE ++ TL H +
Sbjct: 909 SVVPNT---VTEFTITRLNPATEYEISLNSVRGREESE------------RICTLVHTAM 953
Query: 2097 HGPEIL---DVPSTVQKTPFVTHPGYDTGNGIQLPGTSGQQPSVGQQMIFEEHGFRRTTP 2153
P L ++ T + G I L + ++ + EE P
Sbjct: 954 DNPVDLIATNITPTEALLQWKAPVGEVENYVIVLTHFAVAGETILVDGVSEEFRLVDLLP 1013
Query: 2154 PTTATPIRHRPRPYPPNVGEEIQIGHIPREDVDYHLYPHGPGLNPNAS--TGQEALSQTT 2211
T T + P I D P N AS T Q AL
Sbjct: 1014 STHYTATMYATN--GPLTSGTISTNFSTLLD---------PPANLTASEVTRQSAL---- 1058
Query: 2212 ISWAPFQ-DTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQ 2270
ISW P + + Y+++ TD + V T L GL Y ++++A +D
Sbjct: 1059 ISWQPPRAEIENYVLTYK--STDGSRKELIVDAEDTWIRLEGLLENTDYTVLLQAAQDTT 1116
Query: 2271 RHKVREEVVTVGNSV 2285
+ T G V
Sbjct: 1117 WSSITSTAFTTGGRV 1131
Score = 237 bits (604), Expect = 1e-61
Identities = 228/901 (25%), Positives = 383/901 (42%), Gaps = 108/901 (11%)
Query: 628 IQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQY 687
++W+ P +++Y++ ++P G + +PG + TI L+PG+ Y
Sbjct: 344 LEWDGPMA--VTEYVISYQPTALGGLQLQQRVPGDWSGVTITELEPGLTY---------- 391
Query: 688 GHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTV 747
++ + + S P+T+ T +TP T IT ++ V W S +
Sbjct: 392 ---NISVYAVISNILSLPITAKVATHLSTPQGLQFKT------ITETTVEVQWEPFSFSF 442
Query: 748 SGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQ 807
G+ + + + + + +PS TS N L PG +YIVNV + E +S S S
Sbjct: 443 DGWEISF-IPKNNEGGVIAQVPSDVTSFNQTGLKPGEEYIVNVVALKEQA-RSPPTSASV 500
Query: 808 TTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYS-PSVEGSSTELNLPETANSVT 866
+T D P V V DT V W P+A + + Y EG T L + +
Sbjct: 501 STVIDGPTQILVRDVSDTVAFVEWIPPRAKVDFILLKYGLVGGEGGRTTFRLQPPLSQYS 560
Query: 867 LSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIM 926
+ L+PG +Y +++ AV ES Q T + +P++L+ T + +
Sbjct: 561 VQALRPGSRYEVSVSAVRGTNESDSATTQFTT-------EIDAPKNLRVGSRTATSLDLE 613
Query: 927 WTPPESAVTGYRVDVIPVNLPGEHGQRLPISR----NTFAEVTGLSPGVTYYFKVFAVSH 982
W E+ V Y+ V+ L GE + + R T A +T L PG Y + AV +
Sbjct: 614 WDNSEAEVQEYK--VVYSTLAGEQYHEVLVPRGIGPTTRATLTDLVPGTEYGVGISAVMN 671
Query: 983 GRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQY 1042
++S P T T+LD+P +L +++++ + WT I YR+T G +
Sbjct: 672 SQQSVPATMNARTELDSPRDLMVTASSETSISLIWTKASGPIDHYRITF-TPSSGIASEV 730
Query: 1043 NVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKAT-GVFTTLQPGSSIPPYNTEVTET 1101
V + Y L +L+P +EY +S+ A +G Q+S ++T FT +P S + + + VT +
Sbjct: 731 TVPKDRTSYTLTDLEPGAEYIISVTAERGRQQSLESTVDAFTGFRPISHL--HFSHVTSS 788
Query: 1102 TIVITWT----PAPRIGFKLGVRPSQGGEAPREVTSDSGS--IVVSGLTPGVEYVYTIQV 1155
++ ITW+ PA R+ L P E EV+ D+ V+ GL P EY+ + V
Sbjct: 789 SVNITWSDPSPPADRL--ILNYSPRDEEEEMMEVSLDATKRHAVLMGLQPATEYIVNL-V 845
Query: 1156 LRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNG 1215
G PIV + T + PP ++ + +N + VSW YR++ PT
Sbjct: 846 AVHGTVTSEPIVGSITTGIDPPKDITI-SNVTKDSVMVSWS-PPVASFDYYRVSYRPT-- 901
Query: 1216 QQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPEVPQLTDLSF 1275
Q G VV + T L+P EY +S+ +V+ +ES I + + DL
Sbjct: 902 QVGRLDSSVVPNTVTEFTITRLNPATEYEISLNSVRGREESERICTLVHTAMDNPVDLIA 961
Query: 1276 VDITDSSIGLRW-TPLNSSTIIGYRITV---VAAGEGIPIFEDFVDSSVGYYTVTGLEPG 1331
+IT + L+W P+ + Y I + AGE I VD + + L P
Sbjct: 962 TNITPTEALLQWKAPVGE--VENYVIVLTHFAVAGETI-----LVDGVSEEFRLVDLLPS 1014
Query: 1332 IDYDISVITLINGGESAPTTLTQ-QTAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFL 1390
Y ++ NG ++ T T T + PP +L + + + ++W PP + ++ N++
Sbjct: 1015 THYTATMYA-TNGPLTSGTISTNFSTLLDPPANLTASEVTRQSALISWQPPRA-EIENYV 1072
Query: 1391 VRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLD 1450
+ Y EL + D + L LL T+Y V + + +
Sbjct: 1073 LTYKSTDGSR--KELIVDAEDTWIRLEGLLENTDYTVLLQAAQD---------------- 1114
Query: 1451 SPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLT 1510
+S IT+ +FT TG R+ HP +D H N TL+ +
Sbjct: 1115 ----TTWSSITSTAFT----------TGGRVFPHP--------QDCAQHLMNGDTLSGVY 1152
Query: 1511 P 1511
P
Sbjct: 1153 P 1153
Score = 166 bits (421), Expect = 2e-40
Identities = 159/647 (24%), Positives = 273/647 (42%), Gaps = 42/647 (6%)
Query: 610 GPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIK 669
GP ++ + + ++W P+ + + +L++ G + L+ Y+++
Sbjct: 506 GPTQILVRDVSDTVAF--VEWIPPR-AKVDFILLKYGLVGGEGGRTTFRLQPPLSQYSVQ 562
Query: 670 GLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVT 729
L+PG YE + +++ + FTT N G T S + S
Sbjct: 563 ALRPGSRYEVSVSAVRGTNESDSATTQFTT---EIDAPKNLRVGSRTATSLDLEWDNSEA 619
Query: 730 EITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVN 789
E+ V S T++G + L G P T + DL+PG +Y V
Sbjct: 620 EVQEYKVVYS------TLAGEQYHEVLVPRGIGP--------TTRATLTDLVPGTEYGVG 665
Query: 790 VYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSV 849
+ + + +QS+ + + T D+P D V +TSI + W++ PI YRI ++PS
Sbjct: 666 ISAVM-NSQQSVPATMNARTELDSPRDLMVTASSETSISLIWTKASGPIDHYRITFTPS- 723
Query: 850 EGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPS 909
G ++E+ +P+ S TL+DL+PG +Y I++ A Q+S + T P S
Sbjct: 724 SGIASEVTVPKDRTSYTLTDLEPGAEYIISVTAERGRQQSLESTVDAFTGFRPISH---- 779
Query: 910 PRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSP 969
L F VT V I W+ P ++ P + E + + A + GL P
Sbjct: 780 ---LHFSHVTSSSVNITWSDPSPPADRLILNYSPRDEEEEMMEVSLDATKRHAVLMGLQP 836
Query: 970 GVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRL 1029
Y + AV S+P+ TT +D P ++ N T +V+V W+PP A YR+
Sbjct: 837 ATEYIVNLVAVHGTVTSEPIVGSITTGIDPPKDITISNVTKDSVMVSWSPPVASFDYYRV 896
Query: 1030 TVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPK-ATGVFTTLQPG 1088
+ T+ G+ V +V+++ + L PA+EY +SL +++G +ES + T V T +
Sbjct: 897 SYRPTQVGRLDSSVVPNTVTEFTITRLNPATEYEISLNSVRGREESERICTLVHTAMD-- 954
Query: 1089 SSIPPYNTEVTETTIVITW-TPAPRIGFKLGVRP--SQGGEAPREVTSDSGSIVVSGLTP 1145
+ + T +T T ++ W P + + V + GE V S + L P
Sbjct: 955 NPVDLIATNITPTEALLQWKAPVGEVENYVIVLTHFAVAGETIL-VDGVSEEFRLVDLLP 1013
Query: 1146 GVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITG 1205
Y T+ +G I T L PP NL L +SW+ +I
Sbjct: 1014 STHYTATMYA-TNGPLTSGTISTNFSTLLDPPANLTASEVTRQSAL-ISWQ-PPRAEIEN 1070
Query: 1206 YRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKD 1252
Y +T T+G + E +V A+ + + L +Y V + +D
Sbjct: 1071 YVLTYKSTDGSR---KELIVDAEDTWIRLEGLLENTDYTVLLQAAQD 1114
>gi|62988324 tenascin N [Homo sapiens]
Length = 1299
Score = 316 bits (810), Expect = 2e-85
Identities = 233/805 (28%), Positives = 375/805 (46%), Gaps = 26/805 (3%)
Query: 1273 LSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGI 1332
L + T+ S+ + W P SS + Y ++ G+ + + V Y + GL PG
Sbjct: 268 LQLLKNTEDSLLVSWEP--SSQVDHYLLSYYPLGKELSGKQIQVPKEQHSYEILGLLPGT 325
Query: 1333 DYDISVITLINGGESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVR 1392
Y +++ + N S+P L T + T+ +++ V W P S ++ + +R
Sbjct: 326 KYIVTLRNVKNEVSSSPQHLLATTDLAVLGTAWVTDETENSLDVEWENP-STEVDYYKLR 384
Query: 1393 YSPVKNEEDVAELSISPSDNAVV---LTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGL 1449
Y P+ +E VAE+++ S + +T L PGTEY ++V + + E P+ +T +
Sbjct: 385 YGPMTGQE-VAEVTVPKSSDPKSRYDITGLHPGTEYKITVVPMRGELEGKPILLNGRTEI 443
Query: 1450 DSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNL 1509
DSPT + +T ++ TV W +A I Y +R+ G +E V +S LT L
Sbjct: 444 DSPTNVVTDRVTEDTATVSWDPVQAVIDKYVVRYTSA--DGDTKEMAVHKDESSTVLTGL 501
Query: 1510 TPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYY 1569
PG Y V + A G + S T D P +L T + ISWD T+ Y
Sbjct: 502 KPGEAYKVYVWAERGNQGSKKADTNALTEIDSPANLVTDRVTENTATISWDPVQATIDKY 561
Query: 1570 RITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINY 1629
+ Y + + +E V +S+ ++GL+PGV+YT+ V+A G +S K N
Sbjct: 562 VVRY-TSADDQETREVLVGKEQSSTVLTGLRPGVEYTVHVWAQKGDRES----KKADTNA 616
Query: 1630 RTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMT 1689
T+ID P + V +N +V W P + + Y V T + G T+ G +Q+
Sbjct: 617 PTDIDSPKNLVTDRVTENMATVSWDPVQAAIDKYVVRYT--SAGGETREVPVGKEQSSTV 674
Query: 1690 IEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQ 1749
+ GL+P +EY+V V+AQ ES+ A T+ID P+ L V + ++W+ +
Sbjct: 675 LTGLRPGMEYMVHVWAQKGDQESKKADTKAQTDIDSPQNLVTDRVTENMATVSWDPVRAT 734
Query: 1750 VSRYRVTYSSPEDGIHELFPAPDGEEDTAE-LQGLRPGSEYTVSVVALHDDMESQPLIGT 1808
+ RY V Y+S +DG E P G+E ++ L GLRPG EYTV V A ES+
Sbjct: 735 IDRYVVRYTSAKDG--ETREVPVGKEQSSTVLTGLRPGVEYTVHVWAQKGAQESKKADTK 792
Query: 1809 QSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSV 1868
T I +P +L VT + + W P + Y V T G +E+ + + SS
Sbjct: 793 AQTDIDSPQNLVTDWVTENTATVSWDPVQATIDRYVVHYT--SANGETREVPVGKEQSST 850
Query: 1869 VVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTK 1928
V++GL +Y V V+A K S+ A T + P+ TE T+SW
Sbjct: 851 VLTGLRPGMEYTVHVWAQKGNQESKKADTKAQT--EIDGPKNLVTDWVTENMATVSWDPV 908
Query: 1929 TETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVI 1988
TI + V A+G+T + + + S +TGL+PG +Y ++++ S
Sbjct: 909 QATIDKYMVRYTSADGETR-EVPVGKEHSSTVLTGLRPGMEYMVHVWAQKGAQESKKADT 967
Query: 1989 DASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTE 2048
A T +D P NLR A T + +++W PP A+I GYI+ Y+ P +E+
Sbjct: 968 KAQTELDPPRNLRPSAVTQSGGILTWTPPSAQIHGYILTYQFPDGTVKEMQLGRED--QR 1025
Query: 2049 ATITGLEPGTEYTIYVIALKNNQKS 2073
+ GLE G Y + ++A K ++S
Sbjct: 1026 FALQGLEQGATYPVSLVAFKGGRRS 1050
Score = 313 bits (801), Expect = 2e-84
Identities = 226/760 (29%), Positives = 348/760 (45%), Gaps = 31/760 (4%)
Query: 1358 VPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLT 1417
V P L+ D++ V+W P +D ++L+ Y P+ E ++ + ++ +
Sbjct: 262 VVTPQGLQLLKNTEDSLLVSWEPSSQVD--HYLLSYYPLGKELSGKQIQVPKEQHSYEIL 319
Query: 1418 NLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATIT 1477
LLPGT+Y+V++ +V + S+P T L +D T NS V W P +
Sbjct: 320 GLLPGTKYIVTLRNVKNEVSSSPQHLLATTDLAVLGTAWVTDETENSLDVEWENPSTEVD 379
Query: 1478 GYRIRHHPEHFSGRP-REDRVPHS---RNSITLTNLTPGTEYVVSIVALNGREESPLLIG 1533
Y++R+ P +G+ E VP S ++ +T L PGTEY +++V + G E ++
Sbjct: 380 YYKLRYGP--MTGQEVAEVTVPKSSDPKSRYDITGLHPGTEYKITVVPMRGELEGKPILL 437
Query: 1534 QQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKST 1593
T D P ++ T + +SWD + Y + Y G++ +E V +S+
Sbjct: 438 NGRTEIDSPTNVVTDRVTEDTATVSWDPVQAVIDKYVVRYTSADGDT--KEMAVHKDESS 495
Query: 1594 ATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKW 1653
++GLKPG Y + V+A G SK N TEID P+ + V +N+ ++ W
Sbjct: 496 TVLTGLKPGEAYKVYVWAERGN----QGSKKADTNALTEIDSPANLVTDRVTENTATISW 551
Query: 1654 LPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQ 1713
P + + Y V T + T+ G +Q+ + GL+P VEY V V+AQ ES+
Sbjct: 552 DPVQATIDKYVVRYTSADDQ-ETREVLVGKEQSSTVLTGLRPGVEYTVHVWAQKGDRESK 610
Query: 1714 PLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDG 1773
A T+ID PK L V + ++W+ Q + +Y V Y+S E+ P G
Sbjct: 611 KADTNAPTDIDSPKNLVTDRVTENMATVSWDPVQAAIDKYVVRYTSAGGETREV---PVG 667
Query: 1774 EEDTAE-LQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQ 1832
+E ++ L GLRPG EY V V A D ES+ T I +P +L +VT +
Sbjct: 668 KEQSSTVLTGLRPGMEYMVHVWAQKGDQESKKADTKAQTDIDSPQNLVTDRVTENMATVS 727
Query: 1833 WTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTS 1892
W P + Y VR T K G +E+ + + SS V++GL +Y V V+A K S
Sbjct: 728 WDPVRATIDRYVVRYT-SAKDGETREVPVGKEQSSTVLTGLRPGVEYTVHVWAQKGAQES 786
Query: 1893 RPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTI 1952
+ A T ++ P+ TE T T+SW TI + V ANG+T + +
Sbjct: 787 KKADTKAQT--DIDSPQNLVTDWVTENTATVSWDPVQATIDRYVVHYTSANGETR-EVPV 843
Query: 1953 KPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLV 2012
+ S +TGL+PG +Y ++++ N S A T ID P NL T N V
Sbjct: 844 GKEQSSTVLTGLRPGMEYTVHVWAQKGNQESKKADTKAQTEIDGPKNLVTDWVTENMATV 903
Query: 2013 SWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQK 2072
SW P +A I Y+++Y REV T +TGL PG EY ++V A K Q+
Sbjct: 904 SWDPVQATIDKYMVRYTSADGETREVPVGKEHSST--VLTGLRPGMEYMVHVWAQKGAQE 961
Query: 2073 SEPLIGRKKTDELPQLVTLPHPNLHGPEILDVPSTVQKTP 2112
S KK D Q P NL + + TP
Sbjct: 962 S------KKADTKAQTELDPPRNLRPSAVTQSGGILTWTP 995
Score = 270 bits (691), Expect = 1e-71
Identities = 198/646 (30%), Positives = 299/646 (46%), Gaps = 25/646 (3%)
Query: 1447 TGLD-----SPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSR 1501
TGLD +P G+ T +S V W P + + Y + ++P ++ +VP +
Sbjct: 255 TGLDCAQVVTPQGLQLLKNTEDSLLVSW-EPSSQVDHYLLSYYPLGKELSGKQIQVPKEQ 313
Query: 1502 NSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDA 1561
+S + L PGT+Y+V++ + S +T V V T SL + W+
Sbjct: 314 HSYEILGLLPGTKYIVTLRNVKNEVSSSPQHLLATTDLAVLGTAWVTDETENSLDVEWEN 373
Query: 1562 PAVTVRYYRITYGETGGNSPVQEFTVPGS---KSTATISGLKPGVDYTITVYAVTGRGDS 1618
P+ V YY++ YG G V E TVP S KS I+GL PG +Y ITV + G
Sbjct: 374 PSTEVDYYKLRYGPMTGQE-VAEVTVPKSSDPKSRYDITGLHPGTEYKITVVPMRGE--- 429
Query: 1619 PASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKT 1678
KPI +N RTEID P+ + V +++ +V W P + + Y V T + G TK
Sbjct: 430 -LEGKPILLNGRTEIDSPTNVVTDRVTEDTATVSWDPVQAVIDKYVVRYT--SADGDTKE 486
Query: 1679 KTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDS 1738
D++ + GL+P Y V V+A+ + S+ A+T ID P L V ++
Sbjct: 487 MAVHKDESSTVLTGLKPGEAYKVYVWAERGNQGSKKADTNALTEIDSPANLVTDRVTENT 546
Query: 1739 IKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAE-LQGLRPGSEYTVSVVALH 1797
I+W+ Q + +Y V Y+S +D E G+E ++ L GLRPG EYTV V A
Sbjct: 547 ATISWDPVQATIDKYVVRYTSADD--QETREVLVGKEQSSTVLTGLRPGVEYTVHVWAQK 604
Query: 1798 DDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMK 1857
D ES+ T I +P +L +VT + W P + Y VR T G +
Sbjct: 605 GDRESKKADTNAPTDIDSPKNLVTDRVTENMATVSWDPVQAAIDKYVVRYT--SAGGETR 662
Query: 1858 EINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDAT 1917
E+ + + SS V++GL +Y V V+A K S+ A T ++ P+ T
Sbjct: 663 EVPVGKEQSSTVLTGLRPGMEYMVHVWAQKGDQESKKADTKAQT--DIDSPQNLVTDRVT 720
Query: 1918 ETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTL 1977
E T+SW TI + V A + + + S +TGL+PG +Y ++++
Sbjct: 721 ENMATVSWDPVRATIDRYVVRYTSAKDGETREVPVGKEQSSTVLTGLRPGVEYTVHVWAQ 780
Query: 1978 NDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPRE 2037
S A T ID+P NL T N+ VSW P +A I Y++ Y RE
Sbjct: 781 KGAQESKKADTKAQTDIDSPQNLVTDWVTENTATVSWDPVQATIDRYVVHYTSANGETRE 840
Query: 2038 VVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTD 2083
V T +TGL PG EYT++V A K NQ+S+ + +T+
Sbjct: 841 VPVGKEQSST--VLTGLRPGMEYTVHVWAQKGNQESKKADTKAQTE 884
Score = 261 bits (667), Expect = 6e-69
Identities = 221/826 (26%), Positives = 366/826 (44%), Gaps = 39/826 (4%)
Query: 907 VPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVN--LPGEHGQRLPISRNTFAEV 964
V +P+ LQ ++ T+ + + W P S V Y + P+ L G+ Q +P ++++ E+
Sbjct: 262 VVTPQGLQLLKNTEDSLLVSWEP-SSQVDHYLLSYYPLGKELSGKQIQ-VPKEQHSY-EI 318
Query: 965 TGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQI 1024
GL PG Y + V + S P TT L +ET++++ V W P ++
Sbjct: 319 LGLLPGTKYIVTLRNVKNEVSSSPQHLLATTDLAVLGTAWVTDETENSLDVEWENPSTEV 378
Query: 1025 TGYRLTVGLTRRGQPRQYNVGPS---VSKYPLRNLQPASEYTVSLVAIKGNQE-SPKATG 1080
Y+L G + + V S S+Y + L P +EY +++V ++G E P
Sbjct: 379 DYYKLRYGPMTGQEVAEVTVPKSSDPKSRYDITGLHPGTEYKITVVPMRGELEGKPILLN 438
Query: 1081 VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVR--PSQGGEAPREVTSDSGSI 1138
T + +++ VTE T ++W P + K VR + G V D S
Sbjct: 439 GRTEIDSPTNV--VTDRVTEDTATVSWDPVQAVIDKYVVRYTSADGDTKEMAVHKDESST 496
Query: 1139 VVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERS 1198
V++GL PG Y + R Q N +T + P NL + + T+SW+
Sbjct: 497 VLTGLKPGEAYKVYVWAERGNQGSKKADTN-ALTEIDSPANLVTDRVTE-NTATISWD-P 553
Query: 1199 TTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVP 1258
I Y + T + Q+ + E +V +QSS L PG+EY V V+ K D+ES
Sbjct: 554 VQATIDKYVVRYTSADDQE--TREVLVGKEQSSTVLTGLRPGVEYTVHVWAQKGDRESKK 611
Query: 1259 ISDTIIPEVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAG---EGIPIFEDF 1315
++ +L +T++ + W P+ ++ I Y + +AG +P+ ++
Sbjct: 612 ADTNAPTDIDSPKNLVTDRVTENMATVSWDPVQAA-IDKYVVRYTSAGGETREVPVGKE- 669
Query: 1316 VDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAVPPPTDLRFTNIGPDTMR 1375
SS +TGL PG++Y + V ES QT + P +L + +
Sbjct: 670 -QSST---VLTGLRPGMEYMVHVWAQKGDQESKKADTKAQTDIDSPQNLVTDRVTENMAT 725
Query: 1376 VTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQ 1435
V+W P + ++VRY+ K+ E E+ + ++ VLT L PG EY V V +
Sbjct: 726 VSW-DPVRATIDRYVVRYTSAKDGE-TREVPVGKEQSSTVLTGLRPGVEYTVHVWAQKGA 783
Query: 1436 HESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPRED 1495
ES + +T +DSP + +T N+ TV W +ATI Y + H +G RE
Sbjct: 784 QESKKADTKAQTDIDSPQNLVTDWVTENTATVSWDPVQATIDRYVV--HYTSANGETREV 841
Query: 1496 RVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSL 1555
V ++S LT L PG EY V + A G +ES + T D P++L T
Sbjct: 842 PVGKEQSSTVLTGLRPGMEYTVHVWAQKGNQESKKADTKAQTEIDGPKNLVTDWVTENMA 901
Query: 1556 LISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGR 1615
+SWD T+ Y + Y T + +E V S+ ++GL+PG++Y + V+A G
Sbjct: 902 TVSWDPVQATIDKYMVRY--TSADGETREVPVGKEHSSTVLTGLRPGMEYMVHVWAQKGA 959
Query: 1616 GDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGP 1675
+ SK +TE+D P ++ + V + + W P S+ + GY +T + G
Sbjct: 960 QE----SKKADTKAQTELDPPRNLRPSAVTQSGGILTWTPPSAQIHGYILTY--QFPDGT 1013
Query: 1676 TKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVT 1721
K G + ++GL+ Y VS+ A S+ + T T
Sbjct: 1014 VKEMQLGREDQRFALQGLEQGATYPVSLVAFKGGRRSRNVSTTLST 1059
Score = 225 bits (574), Expect = 4e-58
Identities = 227/841 (26%), Positives = 360/841 (42%), Gaps = 61/841 (7%)
Query: 636 SHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRF 695
S + Y+L + P K+ +P +SY I GL PG T++
Sbjct: 286 SQVDHYLLSYYPLGKELSGKQIQVPKEQHSYEILGLLPG------------------TKY 327
Query: 696 DFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYE 755
T + V+S+ T ++ T+ VT+ T +S V W + S V +++ Y
Sbjct: 328 IVTLRNVKNEVSSSPQHLLATTDLAVLGTA-WVTDETENSLDVEWENPSTEVDYYKLRYG 386
Query: 756 LSEEGDEPQYLDLPSTA---TSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPD 812
G E + +P ++ + +I L PG +Y + V + + E IL +T D
Sbjct: 387 -PMTGQEVAEVTVPKSSDPKSRYDITGLHPGTEYKITVVPMRGELEGKPILLNGRTEI-D 444
Query: 813 APPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQP 872
+P + D+V + + V W QA I Y + Y+ S +G + E+ + + +S L+ L+P
Sbjct: 445 SPTNVVTDRVTEDTATVSWDPVQAVIDKYVVRYT-SADGDTKEMAVHKDESSTVLTGLKP 503
Query: 873 GVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPES 932
G Y + ++A NQ S + T + SP +L VT+ TI W P ++
Sbjct: 504 GEAYKVYVWAERGNQGS-------KKADTNALTEIDSPANLVTDRVTENTATISWDPVQA 556
Query: 933 AVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQ 992
+ Y V + E + L + +TGL PGV Y V+A RESK
Sbjct: 557 TIDKYVVRYTSAD-DQETREVLVGKEQSSTVLTGLRPGVEYTVHVWAQKGDRESKKADTN 615
Query: 993 QTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYP 1052
T +D+P NL T++ V W P +A I Y + + G+ R+ VG S
Sbjct: 616 APTDIDSPKNLVTDRVTENMATVSWDPVQAAIDKYVVRY-TSAGGETREVPVGKEQSSTV 674
Query: 1053 LRNLQPASEYTVSLVAIKGNQESPKA-TGVFTTLQPGSSIPPYNTEVTETTIVITWTPAP 1111
L L+P EY V + A KG+QES KA T T + ++ VTE ++W P
Sbjct: 675 LTGLRPGMEYMVHVWAQKGDQESKKADTKAQTDIDSPQNL--VTDRVTENMATVSWDPVR 732
Query: 1112 RIGFKLGVR--PSQGGEAPREVT--SDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIV 1167
+ VR ++ GE REV + S V++GL PGVEY + + QE
Sbjct: 733 ATIDRYVVRYTSAKDGET-REVPVGKEQSSTVLTGLRPGVEYTVHVWAQKGAQE-SKKAD 790
Query: 1168 NKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHA 1227
K T + P NL + + TVSW+ I Y + T NG+ + E V
Sbjct: 791 TKAQTDIDSPQNLVTDWVTE-NTATVSWD-PVQATIDRYVVHYTSANGE---TREVPVGK 845
Query: 1228 DQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPEVPQLTDLSFVDITDSSIGLRW 1287
+QSS L PG+EY V V+ K ++ES E+ +L +T++ + W
Sbjct: 846 EQSSTVLTGLRPGMEYTVHVWAQKGNQESKKADTKAQTEIDGPKNLVTDWVTENMATVSW 905
Query: 1288 TPLNSSTIIGYRITVVAA-GE--GIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLING 1344
P+ +TI Y + +A GE +P+ ++ + +TGL PG++Y + V
Sbjct: 906 DPV-QATIDKYMVRYTSADGETREVPVGKEHSST-----VLTGLRPGMEYMVHVWAQKGA 959
Query: 1345 GESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAE 1404
ES QT + PP +LR + + +TW PPS + +++ Y + V E
Sbjct: 960 QESKKADTKAQTELDPPRNLRPSAVTQSGGILTWT-PPSAQIHGYILTYQ--FPDGTVKE 1016
Query: 1405 LSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKT-GLDSPTGIDFSDITAN 1463
+ + D L L G Y VS+ + S + T G P D S + N
Sbjct: 1017 MQLGREDQRFALQGLEQGATYPVSLVAFKGGRRSRNVSTTLSTVGARFPHPSDCSQVQQN 1076
Query: 1464 S 1464
S
Sbjct: 1077 S 1077
Score = 220 bits (560), Expect = 2e-56
Identities = 210/756 (27%), Positives = 330/756 (43%), Gaps = 57/756 (7%)
Query: 619 TPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNS---YTIKGLKPGV 675
T NS ++W P + + Y LR+ P E T+P + Y I GL PG
Sbjct: 360 TDETENSLDVEWENPS-TEVDYYKLRYGPMTGQ-EVAEVTVPKSSDPKSRYDITGLHPGT 417
Query: 676 VYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASS 735
Y+ ++ ++ G E P+ N G T SP ++ VTE TA+
Sbjct: 418 EYKITVVPMR--GELE-----------GKPILLN---GRTEIDSPTNVVTDRVTEDTAT- 460
Query: 736 FVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISE 795
VSW + + V Y S +GD + + + +S + L PG Y VY +E
Sbjct: 461 --VSWDPVQAVIDKYVVRYT-SADGDTKE-MAVHKDESSTVLTGLKPGEAY--KVYVWAE 514
Query: 796 DGEQ-SLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSST 854
G Q S T+ T D+P + D+V + + + W QA I Y + Y+ + + +
Sbjct: 515 RGNQGSKKADTNALTEIDSPANLVTDRVTENTATISWDPVQATIDKYVVRYTSADDQETR 574
Query: 855 ELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQ 914
E+ + + +S L+ L+PGV+Y + ++A + ++ES ++ T P + SP++L
Sbjct: 575 EVLVGKEQSSTVLTGLRPGVEYTVHVWAQKGDRES-----KKADTNAPTD--IDSPKNLV 627
Query: 915 FVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEV-TGLSPGVTY 973
VT+ T+ W P ++A+ Y V+ G + +P+ + + V TGL PG+ Y
Sbjct: 628 TDRVTENMATVSWDPVQAAIDKY---VVRYTSAGGETREVPVGKEQSSTVLTGLRPGMEY 684
Query: 974 YFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGL 1033
V+A +ESK + T +D+P NL T++ V W P RA I Y +
Sbjct: 685 MVHVWAQKGDQESKKADTKAQTDIDSPQNLVTDRVTENMATVSWDPVRATIDRYVVRYTS 744
Query: 1034 TRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKA-TGVFTTLQPGSSIP 1092
+ G+ R+ VG S L L+P EYTV + A KG QES KA T T + ++
Sbjct: 745 AKDGETREVPVGKEQSSTVLTGLRPGVEYTVHVWAQKGAQESKKADTKAQTDIDSPQNL- 803
Query: 1093 PYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVT--SDSGSIVVSGLTPGVEYV 1150
VTE T ++W P + V + REV + S V++GL PG+EY
Sbjct: 804 -VTDWVTENTATVSWDPVQATIDRYVVHYTSANGETREVPVGKEQSSTVLTGLRPGMEYT 862
Query: 1151 YTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITT 1210
+ + QE K T + P NL + + + TVSW+ I Y +
Sbjct: 863 VHVWAQKGNQE-SKKADTKAQTEIDGPKNLVTDWVTE-NMATVSWD-PVQATIDKYMVRY 919
Query: 1211 TPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPEVPQL 1270
T +G+ + E V + SS L PG+EY V V+ K +ES E+
Sbjct: 920 TSADGE---TREVPVGKEHSSTVLTGLRPGMEYMVHVWAQKGAQESKKADTKAQTELDPP 976
Query: 1271 TDLSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEP 1330
+L +T S L WTP S+ I GY +T + E + + + GLE
Sbjct: 977 RNLRPSAVTQSGGILTWTP-PSAQIHGYILTYQFPDGTVK--EMQLGREDQRFALQGLEQ 1033
Query: 1331 GIDYDISVITLINGGESAPTTLTQQTA---VPPPTD 1363
G Y +S++ G S + T T P P+D
Sbjct: 1034 GATYPVSLVAFKGGRRSRNVSTTLSTVGARFPHPSD 1069
Score = 196 bits (499), Expect = 2e-49
Identities = 180/689 (26%), Positives = 289/689 (41%), Gaps = 44/689 (6%)
Query: 1632 EIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIE 1691
++ P +Q+ ++S+ V W PSS V Y ++ P K +Q I
Sbjct: 261 QVVTPQGLQLLKNTEDSLLVSWEPSSQ-VDHYLLSYYPLGKELSGKQIQVPKEQHSYEIL 319
Query: 1692 GLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVS 1751
GL P +Y+V++ S P A T++ TD +S+ + WE+P +V
Sbjct: 320 GLLPGTKYIVTLRNVKNEVSSSPQHLLATTDLAVLGTAWVTDETENSLDVEWENPSTEVD 379
Query: 1752 RYRVTYS--SPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQ 1809
Y++ Y + ++ P + ++ GL PG+EY ++VV + ++E +P++
Sbjct: 380 YYKLRYGPMTGQEVAEVTVPKSSDPKSRYDITGLHPGTEYKITVVPMRGELEGKPILLNG 439
Query: 1810 STAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVV 1869
T I +PT++ +VT + + W P + Y VR T + G KE+ + D SS V
Sbjct: 440 RTEIDSPTNVVTDRVTEDTATVSWDPVQAVIDKYVVRYTSAD--GDTKEMAVHKDESSTV 497
Query: 1870 VSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKT 1929
++GL Y+V V+A + S+ A L + P TE T TISW
Sbjct: 498 LTGLKPGEAYKVYVWAERGNQGSKKAD--TNALTEIDSPANLVTDRVTENTATISWDPVQ 555
Query: 1930 ETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVID 1989
TI + V A+ Q + + + S +TGL+PG +Y ++++ + S +
Sbjct: 556 ATIDKYVVRYTSADDQETREVLVGKEQSSTVLTGLRPGVEYTVHVWAQKGDRESKKADTN 615
Query: 1990 ASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEA 2049
A T ID+P NL T N VSW P +A I Y+++Y G REV T
Sbjct: 616 APTDIDSPKNLVTDRVTENMATVSWDPVQAAIDKYVVRYTSAGGETREVPVGKEQSST-- 673
Query: 2050 TITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTD-ELPQLVTLPHPNLHGPEILDVPSTV 2108
+TGL PG EY ++V A K +Q+S+ + +TD + PQ NL + + +TV
Sbjct: 674 VLTGLRPGMEYMVHVWAQKGDQESKKADTKAQTDIDSPQ-------NLVTDRVTENMATV 726
Query: 2109 QKTPF-VTHPGYDTGNGIQLPGTSGQQPSVGQQMIFEEHGFRRTTPPTTATPIRHRPRPY 2167
P T Y G + + P VG++ T T +R Y
Sbjct: 727 SWDPVRATIDRYVVRYTSAKDGETREVP-VGKEQ-----------SSTVLTGLRPGVE-Y 773
Query: 2168 PPNVGEEIQIGHIPREDVDYHLYPHGPGLNPNASTGQEALSQTTISWAPFQDT-SEYIIS 2226
+V + + D P N T + T+SW P Q T Y++
Sbjct: 774 TVHVWAQKGAQESKKADTKAQTDIDSP---QNLVTDWVTENTATVSWDPVQATIDRYVV- 829
Query: 2227 CHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRH-----KVREEVVTV 2281
H + E + V +S LTGL G Y + V A K Q K + E+
Sbjct: 830 -HYTSANGETREVPVGKEQSSTVLTGLRPGMEYTVHVWAQKGNQESKKADTKAQTEIDGP 888
Query: 2282 GNSVNEGLNQPTDDSCFDPY--TVSHYAV 2308
N V + + + +DP T+ Y V
Sbjct: 889 KNLVTDWVTENMATVSWDPVQATIDKYMV 917
Score = 79.3 bits (194), Expect = 4e-14
Identities = 100/425 (23%), Positives = 161/425 (37%), Gaps = 44/425 (10%)
Query: 1905 VSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQ-TPIQRTIKPDVRSYTITG 1963
V P+ ++ TE ++ +SW ++ + + + P + + Q + + SY I G
Sbjct: 262 VVTPQGLQLLKNTEDSLLVSWEPSSQ-VDHYLLSYYPLGKELSGKQIQVPKEQHSYEILG 320
Query: 1964 LQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITG 2023
L PGT Y + L + + SSP + A+T + T NSL V W+ P +
Sbjct: 321 LLPGTKYIVTLRNVKNEVSSSPQHLLATTDLAVLGTAWVTDETENSLDVEWENPSTEVDY 380
Query: 2024 YIIKY-EKPGSPPREV-VPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKK 2081
Y ++Y G EV VP+ + ITGL PGTEY I V+ ++ + +P++
Sbjct: 381 YKLRYGPMTGQEVAEVTVPKSSDPKSRYDITGLHPGTEYKITVVPMRGELEGKPIL---- 436
Query: 2082 TDELPQLVTLPHPNLHGPEILDVPSTV---QKTPFVTHPGYDTGNGIQLPGTSGQQPSVG 2138
L+G +D P+ V + T +D + + G
Sbjct: 437 --------------LNGRTEIDSPTNVVTDRVTEDTATVSWDPVQAVIDKYVVRYTSADG 482
Query: 2139 QQMIFEEHGFRRTTPPTTATPIRHRPRPYPPNVGEEIQIGHIPREDVDYHLYPHGPGLNP 2198
H +T T P Y V E + D + P
Sbjct: 483 DTKEMAVHKDESSTVLTGLKP----GEAYKVYVWAERGNQGSKKADTNALTEIDSPA--- 535
Query: 2199 NASTGQEALSQTTISWAPFQDTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGAT 2258
N T + + TISW P Q T + + + D+E + V +S LTGL G
Sbjct: 536 NLVTDRVTENTATISWDPVQATIDKYVVRYTSADDQETREVLVGKEQSSTVLTGLRPGVE 595
Query: 2259 YNIIVEALK-DQQRHKVREEVVT--------VGNSVNEGLNQPTDD---SCFDPYTVSHY 2306
Y + V A K D++ K T V + V E + + D + D Y V +
Sbjct: 596 YTVHVWAQKGDRESKKADTNAPTDIDSPKNLVTDRVTENMATVSWDPVQAAIDKYVVRYT 655
Query: 2307 AVGDE 2311
+ G E
Sbjct: 656 SAGGE 660
>gi|93141049 collagen, type XII, alpha 1 short isoform precursor [Homo
sapiens]
Length = 1899
Score = 289 bits (740), Expect = 2e-77
Identities = 253/949 (26%), Positives = 427/949 (44%), Gaps = 57/949 (6%)
Query: 1166 IVNKVVTP--LSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEE 1223
+ N V P L P+NL + VSW + + Y++ P +G G E
Sbjct: 211 LCNSVKGPGDLEAPSNLVISERTHRS-FRVSWT-PPSDSVDRYKVEYYPVSG--GKRQEF 266
Query: 1224 VVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPEVPQLTDLSFVDITDSSI 1283
V ++S +L P EY V+VY+V +D+ S P+ T + L+ D+ +++
Sbjct: 267 YVSRMETSTVLKDLKPETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVVSLNIYDVGPTTM 326
Query: 1284 GLRWTPLNSSTIIGYRITVVAAGEGIPIF--EDFVDSSVGYYTVTGLEPGIDYDISVITL 1341
++W P+ +T GY ++ + P E + +V +T L P +Y ++V +
Sbjct: 327 HVQWQPVGGAT--GYILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAV 384
Query: 1342 INGGESAPTTLTQQTA-VPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEE 1400
++ S P T+ + T +P P DL+ ++ TM V W P P + ++VRY EE
Sbjct: 385 LHDLTSEPVTVREVTLPLPRPQDLKLRDVTHSTMNVFWEPVPG-KVRKYIVRYKTP--EE 441
Query: 1401 DVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTG-LDSPTGIDFSD 1459
DV E+ + S+ + L +L T Y VSVS+V+++ ES P+ ++ T + +PT + ++
Sbjct: 442 DVKEVEVDRSETSTSLKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPAPTNLKITE 501
Query: 1460 ITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSI 1519
+T+ F W + ++ YRI P S + E + N++ NL P T Y VSI
Sbjct: 502 VTSEGFRGTWDHGASDVSLYRITWAPFGSSDK-METILNGDENTLVFENLNPNTIYEVSI 560
Query: 1520 VALNGRE-ESPLLIGQQSTVSDV--------PRDLEVVAATPTSLLISWDAPAVTVRYYR 1570
A+ E ES LIG + T+ + PR+L+V AT SL + WD + V+ YR
Sbjct: 561 TAIYPDESESDDLIGSERTLPILTTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYR 620
Query: 1571 ITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVT-----GRGDSPASSKPI 1625
ITY + G Q T+ G +++ + LKP YTITV ++ GR +KP+
Sbjct: 621 ITYQPSTGEGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPL 680
Query: 1626 SINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQ 1685
+ ++V D ++++V+W + Y++ P G GP + +
Sbjct: 681 NT--------VRNLRVYDPSTSTLNVRWDHAEGNPRQYKLFYAPAAG-GPEELVPIPGNT 731
Query: 1686 TEMTIEGLQPTVEY---VVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIA 1742
+ LQP Y VV VY + G + +T + + R + + +S+ +
Sbjct: 732 NYAILRNLQPDTSYTVTVVPVYTEGDGGRTSDTGRTLMRGLAR--NVQVYNPTPNSLDVR 789
Query: 1743 WESPQGQVSRYRVTYSSPEDGIH--ELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDM 1800
W+ G V +YRV YS P DG E P G L+ L P + Y+V++VAL+ D
Sbjct: 790 WDPAPGPVLQYRVVYS-PVDGTRPSESIVVP-GNTRMVHLERLIPDTLYSVNLVALYSDG 847
Query: 1801 ESQPLIGTQSTAIP--APTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKE 1858
E P Q +P P +L+ T SLS W + + YR+ +P P+ E
Sbjct: 848 EGNPS-PAQGRTLPRSGPRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGD-PIDE 905
Query: 1859 INLAPDS-SSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDAT 1917
P ++V++ L T Y+++V A+ + G T+ + PP+ ++D
Sbjct: 906 YTTVPGRRNNVILQPLQPDTPYKITVIAVYEDGDGGHLTGNGRTV-GLLPPQNIHISDEW 964
Query: 1918 ETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTL 1977
T +SW + G+++ P P++ + ++ SYT+ L P T Y + +Y
Sbjct: 965 YTRFRVSWDPSPSPVLGYKIVYKPVGSNEPMEAFVG-EMTSYTLHNLNPSTTYDVNVYAQ 1023
Query: 1978 NDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPRE 2037
D+ S P+ +T ++L+ ++ V W P RA T Y +K P R
Sbjct: 1024 YDSGLSVPLTDQGTTLYLNVTDLKTYQIGWDTFCVKWSPHRA-ATSYRLKL-SPADGTRG 1081
Query: 2038 VVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELP 2086
R T TGL P T+Y + V N + + ++ T P
Sbjct: 1082 QEITVRGSETSHCFTGLSPDTDYGVTVFVQTPNLEGPGVSVKEHTTVKP 1130
Score = 261 bits (667), Expect = 6e-69
Identities = 250/933 (26%), Positives = 398/933 (42%), Gaps = 51/933 (5%)
Query: 728 VTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYI 787
++E T SF VSW SD+V ++VEY G + Q + TS + DL P +Y+
Sbjct: 229 ISERTHRSFRVSWTPPSDSVDRYKVEY-YPVSGGKRQEFYVSRMETSTVLKDLKPETEYV 287
Query: 788 VNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSP 847
VNVY + ED E S L ++ T P + V T++ V+W +P TGY + Y P
Sbjct: 288 VNVYSVVED-EYSEPLKGTEKTLPVPVVSLNIYDVGPTTMHVQW-QPVGGATGYILSYKP 345
Query: 848 SVEGSST---ELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRS 904
+ T E+ L T N + L+DL P +Y +T+ AV + S PV +++ T PR
Sbjct: 346 VKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEPVTVREVTLPLPR- 404
Query: 905 DTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRN-TFAE 963
P+DL+ +VT + + W P V Y ++ P E + + + R+ T
Sbjct: 405 -----PQDLKLRDVTHSTMNVFWEPVPGKVRKY---IVRYKTPEEDVKEVEVDRSETSTS 456
Query: 964 VTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTK-LDAPTNLQFVNETDSTVLVRWTPPRA 1022
+ L Y V AV ES P+TAQ+TT+ + APTNL+ T W +
Sbjct: 457 LKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPAPTNLKITEVTSEGFRGTWDHGAS 516
Query: 1023 QITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQE-------S 1075
++ YR+T + + + NL P + Y VS+ AI ++ S
Sbjct: 517 DVSLYRITWAPFGSSDKMETILNGDENTLVFENLNPNTIYEVSITAIYPDESESDDLIGS 576
Query: 1076 PKATGVFTTLQPGSSIPPYNTEV---TETTIVITWTPAP-RI-GFKLGVRPS--QGGEAP 1128
+ + TT P S P N +V T ++ + W PA R+ +++ +PS +G E
Sbjct: 577 ERTLPILTTQAPKSG--PRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQT 634
Query: 1129 REVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDT 1188
+ S+V+ L P Y T+ L E PL+ NL + +P T
Sbjct: 635 TTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRV-YDPST 693
Query: 1189 GVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVY 1248
L V W+ + + Y++ P G G + + + NL P Y V+V
Sbjct: 694 STLNVRWDHA-EGNPRQYKLFYAPAAG--GPEELVPIPGNTNYAILRNLQPDTSYTVTVV 750
Query: 1249 TVKDDKESVPISDTIIPEVPQLT-DLSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGE 1307
V + + SDT + L ++ + T +S+ +RW P ++ YR+
Sbjct: 751 PVYTEGDGGRTSDTGRTLMRGLARNVQVYNPTPNSLDVRWDPA-PGPVLQYRVVYSPVDG 809
Query: 1308 GIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAV-PPPTDLRF 1366
P V + + L P Y ++++ L + GE P+ +T P +LR
Sbjct: 810 TRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGRTLPRSGPRNLRV 869
Query: 1367 TNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYV 1426
+++ V W + + + YSP + ++ N V+L L P T Y
Sbjct: 870 FGETTNSLSVAWDHADG-PVQQYRIIYSPTVGDPIDEYTTVPGRRNNVILQPLQPDTPYK 928
Query: 1427 VSVSSVYEQHESTPLRGRQKT-GLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHP 1485
++V +VYE + L G +T GL P I SD F V W + + GY+I + P
Sbjct: 929 ITVIAVYEDGDGGHLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPSPVLGYKIVYKP 988
Query: 1486 EHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDL 1545
S P E V S TL NL P T Y V++ A S L Q +T+ DL
Sbjct: 989 VG-SNEPMEAFV-GEMTSYTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQGTTLYLNVTDL 1046
Query: 1546 EVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDY 1605
+ + + W +P YR+ G QE TV GS+++ +GL P DY
Sbjct: 1047 KTYQIGWDTFCVKW-SPHRAATSYRLKLSPADGTRG-QEITVRGSETSHCFTGLSPDTDY 1104
Query: 1606 TITVYAVTGRGDSPASSKPISINYRTEIDKPSQ 1638
+TV+ T + P +S+ T + KP++
Sbjct: 1105 GVTVFVQTPNLEGPG----VSVKEHTTV-KPTE 1132
Score = 259 bits (661), Expect = 3e-68
Identities = 236/916 (25%), Positives = 391/916 (42%), Gaps = 55/916 (6%)
Query: 997 LDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNL 1056
L+AP+NL T + V WTPP + Y++ G+ +++ V + L++L
Sbjct: 221 LEAPSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSGGKRQEFYVSRMETSTVLKDL 280
Query: 1057 QPASEYTVSLVAIKGNQESPKATGVFTTLQ-PGSSIPPYNTEVTETTIVITWTP-APRIG 1114
+P +EY V++ ++ ++ S G TL P S+ Y +V TT+ + W P G
Sbjct: 281 KPETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVVSLNIY--DVGPTTMHVQWQPVGGATG 338
Query: 1115 FKLGVRPSQGGEAPREVTSDSGSIV----VSGLTPGVEYVYTIQVLRDGQERDAPIVNKV 1170
+ L +P + E R G V ++ L P EY T+Q + + V +V
Sbjct: 339 YILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEPVTVREV 398
Query: 1171 VTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQS 1230
PL P +L L + + V WE P I T + +E V ++
Sbjct: 399 TLPLPRPQDLKLR-DVTHSTMNVFWE--PVPGKVRKYIVRYKTPEEDVKEVE--VDRSET 453
Query: 1231 SCTFDNLSPGLEYNVSVYTVKDDKESVPIS--DTIIPEVPQLTDLSFVDITDSSIGLRWT 1288
S + +L Y VSV V D+ ES P++ +T P VP T+L ++T W
Sbjct: 454 STSLKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRP-VPAPTNLKITEVTSEGFRGTWD 512
Query: 1289 PLNSSTIIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITL------- 1341
+S + YRIT G + E ++ L P Y++S+ +
Sbjct: 513 H-GASDVSLYRITWAPFGSSDKM-ETILNGDENTLVFENLNPNTIYEVSITAIYPDESES 570
Query: 1342 --INGGESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNE 1399
+ G E LT Q P +L+ N +++ V W P S + + + Y P E
Sbjct: 571 DDLIGSERTLPILTTQAPKSGPRNLQVYNATSNSLTVKW-DPASGRVQKYRITYQPSTGE 629
Query: 1400 EDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKT-GLDSPTGIDFS 1458
+ +I N+VVL L P T Y ++VSS+Y E + GR KT L++ +
Sbjct: 630 GNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRVY 689
Query: 1459 DITANSFTVHWIAPRATITGYRIRHHPEHFSGRPRE-DRVPHSRNSITLTNLTPGTEYVV 1517
D + ++ V W Y++ + P +G P E +P + N L NL P T Y V
Sbjct: 690 DPSTSTLNVRWDHAEGNPRQYKLFYAPA--AGGPEELVPIPGNTNYAILRNLQPDTSYTV 747
Query: 1518 SIVAL-----NGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRIT 1572
++V + GR ++ + + R+++V TP SL + WD V YR+
Sbjct: 748 TVVPVYTEGDGGRTSDT----GRTLMRGLARNVQVYNPTPNSLDVRWDPAPGPVLQYRVV 803
Query: 1573 YGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGD---SPASSKPISINY 1629
Y G P + VPG+ + L P Y++ + A+ G+ SPA + + +
Sbjct: 804 YSPVDGTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGRTLPRS- 862
Query: 1630 RTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMT 1689
P ++V NS+SV W + PV YR+ +P G + T + +
Sbjct: 863 -----GPRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVPGRRNNVI 917
Query: 1690 IEGLQPTVEYVVSVYAQNPSGESQPLVQTAVT-NIDRPKGLAFTDVDVDSIKIAWESPQG 1748
++ LQP Y ++V A G+ L T + P+ + +D +++W+
Sbjct: 918 LQPLQPDTPYKITVIAVYEDGDGGHLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPS 977
Query: 1749 QVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGT 1808
V Y++ Y G +E A GE + L L P + Y V+V A +D S PL
Sbjct: 978 PVLGYKIVYKPV--GSNEPMEAFVGEMTSYTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQ 1035
Query: 1809 QSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSV 1868
+T TDLK Q+ + +W+P T YR++++P + T +EI + +S
Sbjct: 1036 GTTLYLNVTDLKTYQIGWDTFCVKWSPHRA-ATSYRLKLSPADGTRG-QEITVRGSETSH 1093
Query: 1869 VVSGLMVATKYEVSVY 1884
+GL T Y V+V+
Sbjct: 1094 CFTGLSPDTDYGVTVF 1109
Score = 244 bits (622), Expect = 1e-63
Identities = 235/925 (25%), Positives = 386/925 (41%), Gaps = 55/925 (5%)
Query: 812 DAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQ 871
+AP + + + S V W+ P + Y++ Y P G E + S L DL+
Sbjct: 222 EAPSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSGGKRQEFYVSRMETSTVLKDLK 281
Query: 872 PGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE 931
P +Y + +Y+V E++ S P+ GT ++ VP L +V + + W P
Sbjct: 282 PETEYVVNVYSVVEDEYSEPL------KGTEKTLPVPVV-SLNIYDVGPTTMHVQWQPVG 334
Query: 932 SAVTGYRVDVIPV-----NLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRES 986
A TGY + PV P E RL + N ++T L P Y V AV H S
Sbjct: 335 GA-TGYILSYKPVKDTEPTRPKE--VRLGPTVNDM-QLTDLVPNTEYAVTVQAVLHDLTS 390
Query: 987 KPLTAQQTT-KLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVG 1045
+P+T ++ T L P +L+ + T ST+ V W P ++ Y + T ++ V
Sbjct: 391 EPVTVREVTLPLPRPQDLKLRDVTHSTMNVFWEPVPGKVRKY-IVRYKTPEEDVKEVEVD 449
Query: 1046 PSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVI 1105
S + L++L + YTVS+ A+ ESP T TT + TEVT
Sbjct: 450 RSETSTSLKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPAPTNLKITEVTSEGFRG 509
Query: 1106 TWTPAPRIGFKLGVRPSQGGEAPREVT---SDSGSIVVSGLTPGVEYVYTIQVLRD---- 1158
TW + + G + + T D ++V L P Y +I +
Sbjct: 510 TWDHGASDVSLYRITWAPFGSSDKMETILNGDENTLVFENLNPNTIYEVSITAIYPDESE 569
Query: 1159 -----GQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPT 1213
G ER PI+ P S P NL + N + LTV W+ + + YRIT P+
Sbjct: 570 SDDLIGSERTLPILT-TQAPKSGPRNLQV-YNATSNSLTVKWD-PASGRVQKYRITYQPS 626
Query: 1214 NGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDT-IIPEVPQLTD 1272
G +GN + Q+S L P Y ++V ++ D E ++ + + +
Sbjct: 627 TG-EGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVRN 685
Query: 1273 LSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAG---EGIPIFEDFVDSSVGYYTVTGLE 1329
L D + S++ +RW + AAG E +PI + Y + L+
Sbjct: 686 LRVYDPSTSTLNVRWDHAEGNPRQYKLFYAPAAGGPEELVPI-----PGNTNYAILRNLQ 740
Query: 1330 PGIDYDISVITLINGGESAPTTLTQQTAVPP-PTDLRFTNIGPDTMRVTWAPPPSIDLTN 1388
P Y ++V+ + G+ T+ T +T + +++ N P+++ V W P P +
Sbjct: 741 PDTSYTVTVVPVYTEGDGGRTSDTGRTLMRGLARNVQVYNPTPNSLDVRWDPAPG-PVLQ 799
Query: 1389 FLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKT- 1447
+ V YSPV + + + V L L+P T Y V++ ++Y E P + +T
Sbjct: 800 YRVVYSPVDGTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGRTL 859
Query: 1448 GLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLT 1507
P + T NS +V W + YRI + P VP RN++ L
Sbjct: 860 PRSGPRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVPGRRNNVILQ 919
Query: 1508 NLTPGTEYVVSIVALNGREESPLLIGQQSTVSDV-PRDLEVVAATPTSLLISWDAPAVTV 1566
L P T Y ++++A+ + L G TV + P+++ + T +SWD V
Sbjct: 920 PLQPDTPYKITVIAVYEDGDGGHLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPSPV 979
Query: 1567 RYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPIS 1626
Y+I Y G N P++ F G ++ T+ L P Y + VYA G S P++
Sbjct: 980 LGYKIVYKPVGSNEPMEAFV--GEMTSYTLHNLNPSTTYDVNVYAQYDSG----LSVPLT 1033
Query: 1627 INYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQT 1686
T + ++ + ++ VKW P + T YR+ +P +G + G +T
Sbjct: 1034 DQGTTLYLNVTDLKTYQIGWDTFCVKWSPHRA-ATSYRLKLSPADGTRGQEITVRG-SET 1091
Query: 1687 EMTIEGLQPTVEYVVSVYAQNPSGE 1711
GL P +Y V+V+ Q P+ E
Sbjct: 1092 SHCFTGLSPDTDYGVTVFVQTPNLE 1116
Score = 201 bits (510), Expect = 1e-50
Identities = 214/835 (25%), Positives = 345/835 (41%), Gaps = 77/835 (9%)
Query: 623 PNSHPIQWNAPQP-SHISKYILRWRPKNSVG--RWKEATIPGHLNSYTIKGLKPGVVYEG 679
P + +QW QP + YIL ++P R KE + +N + L P Y
Sbjct: 323 PTTMHVQW---QPVGGATGYILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYA- 378
Query: 680 QLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSE-SVTEITASSFVV 738
+++Q H TS PVT VT PL + + ++T S+ V
Sbjct: 379 --VTVQAVLHD----------LTSEPVTVREVT------LPLPRPQDLKLRDVTHSTMNV 420
Query: 739 SWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGE 798
W V + V Y+ EE + +D T+TS+ DL Y V+V + ++GE
Sbjct: 421 FWEPVPGKVRKYIVRYKTPEEDVKEVEVDRSETSTSLK--DLFSQTLYTVSVSAVHDEGE 478
Query: 799 QSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNL 858
+ + T AP + + +V W + ++ YRI ++P E L
Sbjct: 479 SPPVTAQETTRPVPAPTNLKITEVTSEGFRGTWDHGASDVSLYRITWAPFGSSDKMETIL 538
Query: 859 PETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQE------TTGTPRSDTVPSPRD 912
N++ +L P Y ++I A+ ++ + +I E TT P+S PR+
Sbjct: 539 NGDENTLVFENLNPNTIYEVSITAIYPDESESDDLIGSERTLPILTTQAPKS----GPRN 594
Query: 913 LQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVT 972
LQ T +T+ W P V YR+ P G R + L P
Sbjct: 595 LQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQTTTIGGRQNSVVLQKLKPDTP 654
Query: 973 YYFKVFAVSHGRESKPLTAQQTTK-LDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTV 1031
Y V ++ E +T + TK L+ NL+ + + ST+ VRW Y+L
Sbjct: 655 YTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRVYDPSTSTLNVRWDHAEGNPRQYKLFY 714
Query: 1032 GLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPG--S 1089
G + + + LRNLQP + YTV++V + + + + TL G
Sbjct: 715 APAAGGPEELVPIPGNTNYAILRNLQPDTSYTVTVVPVYTEGDGGRTSDTGRTLMRGLAR 774
Query: 1090 SIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSG------- 1142
++ YN T ++ + W PAP + V S P + T S SIVV G
Sbjct: 775 NVQVYNP--TPNSLDVRWDPAPGPVLQYRVVYS-----PVDGTRPSESIVVPGNTRMVHL 827
Query: 1143 --LTPGVEY-VYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERST 1199
L P Y V + + DG+ +P + + P S P NL + T L+V+W+ +
Sbjct: 828 ERLIPDTLYSVNLVALYSDGEGNPSPAQGRTL-PRSGPRNLRV-FGETTNSLSVAWDHAD 885
Query: 1200 TPDITGYRITTTPTNGQQGNSLEE--VVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESV 1257
P + YRI +PT G+ ++E V +++ L P Y ++V V +D +
Sbjct: 886 GP-VQQYRIIYSPT---VGDPIDEYTTVPGRRNNVILQPLQPDTPYKITVIAVYEDGDGG 941
Query: 1258 PISD---TIIPEVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIFED 1314
++ T+ PQ +S D + + W P + S ++GY+I G P+ E
Sbjct: 942 HLTGNGRTVGLLPPQNIHIS--DEWYTRFRVSWDP-SPSPVLGYKIVYKPVGSNEPM-EA 997
Query: 1315 FVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAVPPPTDLRFTNIGPDTM 1374
FV YT+ L P YD++V + G S P T T TDL+ IG DT
Sbjct: 998 FVGEMTS-YTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQGTTLYLNVTDLKTYQIGWDTF 1056
Query: 1375 RVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSV 1429
V W+P + T++ ++ SP E+++ S+ + T L P T+Y V+V
Sbjct: 1057 CVKWSPHRA--ATSYRLKLSPADGTRG-QEITVRGSETSHCFTGLSPDTDYGVTV 1108
Score = 152 bits (385), Expect = 3e-36
Identities = 148/634 (23%), Positives = 250/634 (39%), Gaps = 37/634 (5%)
Query: 636 SHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRF 695
S +S Y + W P S + E + G N+ + L P +YE +SI E
Sbjct: 516 SDVSLYRITWAPFGSSDKM-ETILNGDENTLVFENLNPNTIYE---VSITAIYPDESESD 571
Query: 696 DFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYE 755
D + + P+ TT + V T++S V W AS V +R+ Y+
Sbjct: 572 DLIGSERTLPIL-------TTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQ 624
Query: 756 LSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPP 815
S Q + SV + L P Y + V + DGE + +T +
Sbjct: 625 PSTGEGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVR 684
Query: 816 DPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQ 875
+ V +++ VRW + Y++ Y+P+ G + +P N L +LQP
Sbjct: 685 NLRVYDPSTSTLNVRWDHAEGNPRQYKLFYAPAAGGPEELVPIPGNTNYAILRNLQPDTS 744
Query: 876 YNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVT 935
Y +T+ V + T+ T R+ R++Q T + + W P V
Sbjct: 745 YTVTVVPVYTEGDG------GRTSDTGRTLMRGLARNVQVYNPTPNSLDVRWDPAPGPVL 798
Query: 936 GYRVDVIPVNLPGEHGQRLPISRNT-FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQ-Q 993
YRV PV+ + + + NT + L P Y + A+ E P AQ +
Sbjct: 799 QYRVVYSPVD-GTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGR 857
Query: 994 TTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPS-VSKYP 1052
T P NL+ ET +++ V W + YR+ T +Y P +
Sbjct: 858 TLPRSGPRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVPGRRNNVI 917
Query: 1053 LRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTE---TTIVITW-- 1107
L+ LQP + Y ++++A+ + + TG T+ +PP N +++ T ++W
Sbjct: 918 LQPLQPDTPYKITVIAVYEDGDGGHLTGNGRTV---GLLPPQNIHISDEWYTRFRVSWDP 974
Query: 1108 TPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIV 1167
+P+P +G+K+ +P E + S + L P Y + D P+
Sbjct: 975 SPSPVLGYKIVYKPVGSNEPMEAFVGEMTSYTLHNLNPSTTYDVNVYAQYD-SGLSVPLT 1033
Query: 1168 NKVVTPLSPPTNLH-LEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVH 1226
++ T T+L + DT V W S T YR+ +P +G +G E V
Sbjct: 1034 DQGTTLYLNVTDLKTYQIGWDT--FCVKW--SPHRAATSYRLKLSPADGTRGQ--EITVR 1087
Query: 1227 ADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS 1260
++S F LSP +Y V+V+ + E +S
Sbjct: 1088 GSETSHCFTGLSPDTDYGVTVFVQTPNLEGPGVS 1121
Score = 76.3 bits (186), Expect = 4e-13
Identities = 87/374 (23%), Positives = 149/374 (39%), Gaps = 54/374 (14%)
Query: 1904 NVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITG 1963
++ P +++ T + +SW ++++ ++V+ P +G + + S +
Sbjct: 220 DLEAPSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSGGKRQEFYVSRMETSTVLKD 279
Query: 1964 LQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITG 2023
L+P T+Y + +Y++ ++ S P+ T +L P ++ V WQP TG
Sbjct: 280 LKPETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVVSLNIYDVGPTTMHVQWQPVGGA-TG 338
Query: 2024 YIIKYE--KPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKK 2081
YI+ Y+ K P R R P V + +T L P TEY + V A+ ++ SEP+ R+
Sbjct: 339 YILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEPVTVRE- 397
Query: 2082 TDELPQLVTLPHPNLHGPEILDVPSTVQKTPFVTHPG--------YDT-GNGIQLPGTSG 2132
VTLP P ++ DV + + PG Y T ++
Sbjct: 398 -------VTLPLPRPQDLKLRDVTHSTMNVFWEPVPGKVRKYIVRYKTPEEDVKEVEVDR 450
Query: 2133 QQPSVGQQMIFEEHGF---------RRTTPPTTATPIRHRPRPYPPNVGEEIQIGHIPRE 2183
+ S + +F + + +PP TA RP P P N ++I + E
Sbjct: 451 SETSTSLKDLFSQTLYTVSVSAVHDEGESPPVTAQETT-RPVPAPTN----LKITEVTSE 505
Query: 2184 DVDYHLYPHGPGLNPNASTGQEALSQTTISWAPF--QDTSEYIISCHPVGTDEEPLQFR- 2240
G G +S I+WAPF D E I++ DE L F
Sbjct: 506 -----------GFRGTWDHGASDVSLYRITWAPFGSSDKMETILN-----GDENTLVFEN 549
Query: 2241 -VPGTSTSATLTGL 2253
P T ++T +
Sbjct: 550 LNPNTIYEVSITAI 563
Score = 65.9 bits (159), Expect = 5e-10
Identities = 75/320 (23%), Positives = 125/320 (39%), Gaps = 32/320 (10%)
Query: 595 GEWHCQPLQ--TYPSSSGP--VEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNS 650
GE + P Q T P S GP + VF T NS + W+ + +Y + + P
Sbjct: 847 GEGNPSPAQGRTLPRS-GPRNLRVFGETT----NSLSVAWDHAD-GPVQQYRIIYSPTVG 900
Query: 651 VGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNT 710
+ T+PG N+ ++ L+P Y+ +I++ + G
Sbjct: 901 DPIDEYTTVPGRRNNVILQPLQPDTPYKITVIAVYEDGD------------------GGH 942
Query: 711 VTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPS 770
+TG L + +++ + F VSW + V G+++ Y+ G
Sbjct: 943 LTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPSPVLGYKIVYK--PVGSNEPMEAFVG 1000
Query: 771 TATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVR 830
TS + +L P Y VNVY + G S+ L+ TT D Q+ + V+
Sbjct: 1001 EMTSYTLHNLNPSTTYDVNVYAQYDSG-LSVPLTDQGTTLYLNVTDLKTYQIGWDTFCVK 1059
Query: 831 WSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQEST 890
WS P T YR+ SP+ E+ + + S + L P Y +T++ N E
Sbjct: 1060 WS-PHRAATSYRLKLSPADGTRGQEITVRGSETSHCFTGLSPDTDYGVTVFVQTPNLEGP 1118
Query: 891 PVVIQQETTGTPRSDTVPSP 910
V +++ TT P P
Sbjct: 1119 GVSVKEHTTVKPTEAPTEPP 1138
>gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]
Length = 2944
Score = 220 bits (561), Expect = 1e-56
Identities = 217/858 (25%), Positives = 372/858 (43%), Gaps = 62/858 (7%)
Query: 988 PLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLT-VGLTRRGQP-----RQ 1041
P+T AP +L + ++ V+WT +TGY++ LT GQP ++
Sbjct: 223 PVTRPPDDSTSAPRDLVLSEPSSQSLRVQWTAASGPVTGYKVQYTPLTGLGQPLPSERQE 282
Query: 1042 YNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVF-TTLQPGSSIPPYNTEVTE 1100
NV + LR L+P +EY V+++A+ N +G TT G + NT T
Sbjct: 283 VNVPAGETSVRLRGLRPLTEYQVTVIALYANSIGEAVSGTARTTALEGPELTIQNT--TA 340
Query: 1101 TTIVITWTPAP-RIGFKLGVRPSQGGEAPR-EVTSDSGSIVVSGLTPGVEYVYTIQVLRD 1158
++++ W P G+++ R GG + E+ GS+++ L PG +Y T+ L
Sbjct: 341 HSLLVAWRSVPGATGYRVTWRVLSGGPTQQQELGPGQGSVLLRDLEPGTDYEVTVSTLF- 399
Query: 1159 GQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQG 1218
G+ T S L T +L +SW + P+ GYR+ G +
Sbjct: 400 GRSVGPATSLMARTDASVEQTLRPVILGPTSIL-LSW--NLVPEARGYRLEWRRETGLEP 456
Query: 1219 NSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPEVPQL-----TDL 1273
+ V+ +D + D L PG EY +++YT+ + E V T++P P+L TDL
Sbjct: 457 PQ-KVVLPSDVTRYQLDGLQPGTEYRLTLYTLLEGHE-VATPATVVPTGPELPVSPVTDL 514
Query: 1274 SFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGID 1333
++ + + W+P+ +T YRI +V + +G+ S + + ++ G+
Sbjct: 515 QATELPGQRVRVSWSPVPGAT--QYRI-IVRSTQGVERTLVLPGSQTAF-DLDDVQAGLS 570
Query: 1334 YDISVITLINGGESAPTTLTQQTAVPPPT---DLRFTNIGPDTMRVTWAPPPSIDLTNFL 1390
Y + V + E + + LT + P LR +RV W P P + F
Sbjct: 571 YTVRVSARVGPREGSASVLTVRREPETPLAVPGLRVVVSDATRVRVAWGPVPGA--SGFR 628
Query: 1391 VRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLD 1450
+ +S E + ++ P A +T L PGT Y V+VS + + E +T
Sbjct: 629 ISWSTGSGPE--SSQTLPPDSTATDITGLQPGTTYQVAVSVLRGREEGPAAVIVARTDPL 686
Query: 1451 SPTG-IDFSDITANSFTVHWI-APRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTN 1508
P + + +++S T+ W P AT GYR+ H H G + V L
Sbjct: 687 GPVRTVHVTQASSSSVTITWTRVPGAT--GYRVSWHSAH--GPEKSQLVSGEATVAELDG 742
Query: 1509 LTPGTEYVVSIVA----LNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAV 1564
L P TEY V + A ++G S ++ V V R L+++ A+ L I+W
Sbjct: 743 LEPDTEYTVHVRAHVAGVDGPPASVVVRTAPEPVGRVSR-LQILNASSDVLRITW-VGVT 800
Query: 1565 TVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKP 1624
YR+ +G + G P++ +PG+ +A I GL+ GV Y++ V A+ G + P
Sbjct: 801 GATAYRLAWGRSEGG-PMRHQILPGNTDSAEIRGLEGGVSYSVRVTALVGDREGT----P 855
Query: 1625 ISINYRTEIDKP---SQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTA 1681
+SI T + P + V ++S+ ++W P G+ + P+ G +++
Sbjct: 856 VSIVVTTPPEAPPALGTLHVVQRGEHSLRLRWEPVPR-AQGFLLHWQPEGGQ--EQSRVL 912
Query: 1682 GPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKG--LAFTDVDVDSI 1739
GP+ + ++GL+P +Y V + P+GE TA T R L D +DS+
Sbjct: 913 GPELSSYHLDGLEPATQYRVRLSVLGPAGEGPSAEVTARTESPRVPSIELRVVDTSIDSV 972
Query: 1740 KIAWESPQGQVSRYRVTYSSPEDGIHELFPAPD---GEEDTAELQGLRPGSEYTVSVVAL 1796
+AW +P + S Y +++ E+ +P G + + GL PG Y S+ +
Sbjct: 973 TLAW-TPVSRASSYILSWRPLRGPGQEVPGSPQTLPGISSSQRVTGLEPGVSYIFSLTPV 1031
Query: 1797 HDDMESQPLIGTQSTAIP 1814
D + TQ+ P
Sbjct: 1032 LDGVRGPEASVTQTPVCP 1049
Score = 218 bits (556), Expect = 4e-56
Identities = 223/844 (26%), Positives = 359/844 (42%), Gaps = 56/844 (6%)
Query: 1165 PIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSL--- 1221
P+ S P +L L + P + L V W ++ P +TGY++ TP G G L
Sbjct: 223 PVTRPPDDSTSAPRDLVL-SEPSSQSLRVQWTAASGP-VTGYKVQYTPLTGL-GQPLPSE 279
Query: 1222 --EEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPEVPQLTDLSFVDIT 1279
E V A ++S L P EY V+V + + +S T + +L+ + T
Sbjct: 280 RQEVNVPAGETSVRLRGLRPLTEYQVTVIALYANSIGEAVSGTARTTALEGPELTIQNTT 339
Query: 1280 DSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVI 1339
S+ + W + +T GYR+T G P + + G + LEPG DY+++V
Sbjct: 340 AHSLLVAWRSVPGAT--GYRVTWRVLSGG-PTQQQELGPGQGSVLLRDLEPGTDYEVTVS 396
Query: 1340 TLINGGESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNE 1399
TL T+L +T LR +GP ++ ++W P + + + +
Sbjct: 397 TLFGRSVGPATSLMARTDASVEQTLRPVILGPTSILLSWNLVP--EARGYRLEWRRETGL 454
Query: 1400 EDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSP----TGI 1455
E ++ + L L PGTEY +++ ++ E HE TG + P T +
Sbjct: 455 EPPQKVVLPSDVTRYQLDGLQPGTEYRLTLYTLLEGHEVATPATVVPTGPELPVSPVTDL 514
Query: 1456 DFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEY 1515
+++ V W +P T YRI G R +P S+ + L ++ G Y
Sbjct: 515 QATELPGQRVRVSW-SPVPGATQYRIIVRSTQ--GVERTLVLPGSQTAFDLDDVQAGLSY 571
Query: 1516 VVSIVALNGREE---SPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRIT 1572
V + A G E S L + ++ L VV + T + ++W P +RI+
Sbjct: 572 TVRVSARVGPREGSASVLTVRREPETPLAVPGLRVVVSDATRVRVAW-GPVPGASGFRIS 630
Query: 1573 YGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTE 1632
+ G+ P T+P + I+GL+PG Y + V + GR + PA+ I RT+
Sbjct: 631 WST--GSGPESSQTLPPDSTATDITGLQPGTTYQVAVSVLRGREEGPAAV----IVARTD 684
Query: 1633 IDKPSQ-MQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIE 1691
P + + VT +S+++ W TGYRV+ + GP K++ + T ++
Sbjct: 685 PLGPVRTVHVTQASSSSVTITWTRVPG-ATGYRVSW--HSAHGPEKSQLVSGEATVAELD 741
Query: 1692 GLQPTVEYVVSVYAQNPSGESQP---LVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQG 1748
GL+P EY V V A + P +V+TA + R L + D ++I W G
Sbjct: 742 GLEPDTEYTVHVRAHVAGVDGPPASVVVRTAPEPVGRVSRLQILNASSDVLRITWVGVTG 801
Query: 1749 QVSRYRVTYSSPEDGI--HELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPL- 1805
+ YR+ + E G H++ P G D+AE++GL G Y+V V AL D E P+
Sbjct: 802 ATA-YRLAWGRSEGGPMRHQILP---GNTDSAEIRGLEGGVSYSVRVTALVGDREGTPVS 857
Query: 1806 --IGTQSTAIPAPTDLKFTQVTPTSLSAQWTP-PNVQLTGYRVRVTPKEKTGPMKEINLA 1862
+ T A PA L Q SL +W P P Q G+ + P+ G + L
Sbjct: 858 IVVTTPPEAPPALGTLHVVQRGEHSLRLRWEPVPRAQ--GFLLHWQPEG--GQEQSRVLG 913
Query: 1863 PDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTIT 1922
P+ SS + GL AT+Y V + L A+ T P RV D + ++T
Sbjct: 914 PELSSYHLDGLEPATQYRVRLSVLGPAGEGPSAEVTARTESPRVPSIELRVVDTSIDSVT 973
Query: 1923 ISWRTKTETITGFQVDAVPANG---QTPIQRTIKPDVRS-YTITGLQPGTDYKIYLYTLN 1978
++W T + + + P G + P P + S +TGL+PG Y L +
Sbjct: 974 LAW-TPVSRASSYILSWRPLRGPGQEVPGSPQTLPGISSSQRVTGLEPGVSYIFSLTPVL 1032
Query: 1979 DNAR 1982
D R
Sbjct: 1033 DGVR 1036
Score = 202 bits (514), Expect = 3e-51
Identities = 226/893 (25%), Positives = 371/893 (41%), Gaps = 69/893 (7%)
Query: 696 DFTTTSTSTPVTSN----TVTGETTPFSPLVATSES----VTEITASSFVVSWVSASDTV 747
DF+ T P+ S T G P +TS ++E ++ S V W +AS V
Sbjct: 200 DFSILRTLLPLVSRRVCTTAGGVPVTRPPDDSTSAPRDLVLSEPSSQSLRVQWTAASGPV 259
Query: 748 SGFRVEYE-LSEEGD----EPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLI 802
+G++V+Y L+ G E Q +++P+ TSV + L P +Y V V + + +
Sbjct: 260 TGYKVQYTPLTGLGQPLPSERQEVNVPAGETSVRLRGLRPLTEYQVTVIALYANSIGEAV 319
Query: 803 LSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETA 862
T++TTA + P + T+ S++V W R TGYR+ + G + + L
Sbjct: 320 SGTARTTALEGP-ELTIQNTTAHSLLVAW-RSVPGATGYRVTWRVLSGGPTQQQELGPGQ 377
Query: 863 NSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVK 922
SV L DL+PG Y +T+ + + T + P V +
Sbjct: 378 GSVLLRDLEPGTDYEVTVSTLFGRSVGPATSLMARTDASVEQTLRP-------VILGPTS 430
Query: 923 VTIMWTPPESAVTGYRVDVI-PVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVS 981
+ + W A GYR++ L LP S T ++ GL PG Y ++ +
Sbjct: 431 ILLSWNLVPEA-RGYRLEWRRETGLEPPQKVVLP-SDVTRYQLDGLQPGTEYRLTLYTLL 488
Query: 982 HGRE-SKPLTAQQT---TKLDAPTNLQFVNETDSTVLVRWTP-PRAQITGYRLTVGLTRR 1036
G E + P T T + T+LQ V V W+P P A T YR+ V T+
Sbjct: 489 EGHEVATPATVVPTGPELPVSPVTDLQATELPGQRVRVSWSPVPGA--TQYRIIVRSTQ- 545
Query: 1037 GQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGS--SIPPY 1094
G R + S + + L ++Q YTV + A G +E A+ + +P + ++P
Sbjct: 546 GVERTLVLPGSQTAFDLDDVQAGLSYTVRVSARVGPREG-SASVLTVRREPETPLAVPGL 604
Query: 1095 NTEVTETTIV-ITWTPAPRI-GFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYT 1152
V++ T V + W P P GF++ G E+ + + DS + ++GL PG Y
Sbjct: 605 RVVVSDATRVRVAWGPVPGASGFRISWSTGSGPESSQTLPPDSTATDITGLQPGTTYQVA 664
Query: 1153 IQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTP 1212
+ VLR +E A ++ PL P +H+ + V T++W R P TGYR++
Sbjct: 665 VSVLRGREEGPAAVIVARTDPLGPVRTVHVTQASSSSV-TITWTR--VPGATGYRVSWHS 721
Query: 1213 TNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTI--IPE-VPQ 1269
+G + + L V + + D L P EY V V + P S + PE V +
Sbjct: 722 AHGPEKSQL---VSGEATVAELDGLEPDTEYTVHVRAHVAGVDGPPASVVVRTAPEPVGR 778
Query: 1270 LTDLSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLE 1329
++ L ++ + + + W + +T YR+ EG P+ + + + GLE
Sbjct: 779 VSRLQILNASSDVLRITWVGVTGAT--AYRL-AWGRSEGGPMRHQILPGNTDSAEIRGLE 835
Query: 1330 PGIDYDISVITLINGGESAPTTL---TQQTAVPPPTDLRFTNIGPDTMRVTWAPPPSIDL 1386
G+ Y + V L+ E P ++ T A P L G ++R+ W P P
Sbjct: 836 GGVSYSVRVTALVGDREGTPVSIVVTTPPEAPPALGTLHVVQRGEHSLRLRWEPVPRAQ- 894
Query: 1387 TNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQK 1446
FL+ + P +E L P ++ L L P T+Y V +S + E +
Sbjct: 895 -GFLLHWQPEGGQEQSRVL--GPELSSYHLDGLEPATQYRVRLSVLGPAGEGPSAEVTAR 951
Query: 1447 TGLDSPTGIDFS--DITANSFTVHWIAPRATITGYRIRHHP-----EHFSGRPREDRVPH 1499
T I+ D + +S T+ W P + + Y + P + G P+ +P
Sbjct: 952 TESPRVPSIELRVVDTSIDSVTLAW-TPVSRASSYILSWRPLRGPGQEVPGSPQ--TLPG 1008
Query: 1500 SRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATP 1552
+S +T L PG Y+ S+ + P Q+ V PR L V P
Sbjct: 1009 ISSSQRVTGLEPGVSYIFSLTPVLDGVRGPEASVTQTPV--CPRGLADVVFLP 1059
Score = 201 bits (511), Expect = 7e-51
Identities = 212/810 (26%), Positives = 338/810 (41%), Gaps = 43/810 (5%)
Query: 1272 DLSFVDITDSSIGLRWTPLNSSTIIGYRIT---VVAAGEGIPIFEDFVDSSVGYYTVT-- 1326
DL + + S+ ++WT S + GY++ + G+ +P V+ G +V
Sbjct: 237 DLVLSEPSSQSLRVQWTAA-SGPVTGYKVQYTPLTGLGQPLPSERQEVNVPAGETSVRLR 295
Query: 1327 GLEPGIDYDISVITLINGGESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAPPPSIDL 1386
GL P +Y ++VI L + T +T +L N ++ V W P
Sbjct: 296 GLRPLTEYQVTVIALYANSIGEAVSGTARTTALEGPELTIQNTTAHSLLVAWRSVPGA-- 353
Query: 1387 TNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQK 1446
T + V + V + + + P +V+L +L PGT+Y V+VS+++ + +
Sbjct: 354 TGYRVTWR-VLSGGPTQQQELGPGQGSVLLRDLEPGTDYEVTVSTLFGRSVGPATSLMAR 412
Query: 1447 TGLDSPTGIDFSDITANSFTVHW-IAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSIT 1505
T + + S + W + P A GYR+ E P++ +P
Sbjct: 413 TDASVEQTLRPVILGPTSILLSWNLVPEAR--GYRLEWRRETGLEPPQKVVLPSDVTRYQ 470
Query: 1506 LTNLTPGTEYVVSIVAL-NGRE-ESPLLI---GQQSTVSDVPRDLEVVAATPTSLLISWD 1560
L L PGTEY +++ L G E +P + G + VS V DL+ + +SW
Sbjct: 471 LDGLQPGTEYRLTLYTLLEGHEVATPATVVPTGPELPVSPVT-DLQATELPGQRVRVSW- 528
Query: 1561 APAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPA 1620
+P YRI T G + +PGS++ + ++ G+ YT+ V A G + A
Sbjct: 529 SPVPGATQYRIIVRSTQGVE--RTLVLPGSQTAFDLDDVQAGLSYTVRVSARVGPREGSA 586
Query: 1621 SSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKT 1680
S + T + P ++V + V W P +G+R++ + G GP ++T
Sbjct: 587 SVLTVRREPETPLAVPG-LRVVVSDATRVRVAWGPVPG-ASGFRISWS--TGSGPESSQT 642
Query: 1681 AGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRP-KGLAFTDVDVDSI 1739
PD T I GLQP Y V+V E V A T+ P + + T S+
Sbjct: 643 LPPDSTATDITGLQPGTTYQVAVSVLRGREEGPAAVIVARTDPLGPVRTVHVTQASSSSV 702
Query: 1740 KIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSV---VAL 1796
I W G YRV++ S E GE AEL GL P +EYTV V VA
Sbjct: 703 TITWTRVPGATG-YRVSWHSAHGP--EKSQLVSGEATVAELDGLEPDTEYTVHVRAHVAG 759
Query: 1797 HDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPM 1856
D + ++ T + + L+ + L W T YR+ + + GPM
Sbjct: 760 VDGPPASVVVRTAPEPVGRVSRLQILNASSDVLRITWVGVT-GATAYRL-AWGRSEGGPM 817
Query: 1857 KEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRA-RVTD 1915
+ L ++ S + GL Y V V AL P VVTT P V
Sbjct: 818 RHQILPGNTDSAEIRGLEGGVSYSVRVTALVGDREGTPVSIVVTTPPEAPPALGTLHVVQ 877
Query: 1916 ATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLY 1975
E ++ + W GF + P GQ R + P++ SY + GL+P T Y++ L
Sbjct: 878 RGEHSLRLRWEPVPRA-QGFLLHWQPEGGQEQ-SRVLGPELSSYHLDGLEPATQYRVRLS 935
Query: 1976 TLNDNARSSPVVIDASTAID-APS-NLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGS 2033
L + A T PS LR + T+ +S+ ++W P +R + YI+ +
Sbjct: 936 VLGPAGEGPSAEVTARTESPRVPSIELRVVDTSIDSVTLAWTPV-SRASSYILSWRPLRG 994
Query: 2034 PPREVVPRPR--PGVTEAT-ITGLEPGTEY 2060
P +EV P+ PG++ + +TGLEPG Y
Sbjct: 995 PGQEVPGSPQTLPGISSSQRVTGLEPGVSY 1024
Score = 198 bits (504), Expect = 5e-50
Identities = 198/815 (24%), Positives = 344/815 (42%), Gaps = 45/815 (5%)
Query: 1349 PTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKN-----EEDVA 1403
P T + P DL + ++RV W S +T + V+Y+P+ +
Sbjct: 223 PVTRPPDDSTSAPRDLVLSEPSSQSLRVQWTAA-SGPVTGYKVQYTPLTGLGQPLPSERQ 281
Query: 1404 ELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITAN 1463
E+++ + +V L L P TEY V+V ++Y + G +T + + TA+
Sbjct: 282 EVNVPAGETSVRLRGLRPLTEYQVTVIALYANSIGEAVSGTARTTALEGPELTIQNTTAH 341
Query: 1464 SFTVHWIAPRATITGYRIRHHPEHFSGRP-REDRVPHSRNSITLTNLTPGTEYVVSIVAL 1522
S V W + TGYR+ SG P ++ + + S+ L +L PGT+Y V++ L
Sbjct: 342 SLLVAWRSVPGA-TGYRVTWRV--LSGGPTQQQELGPGQGSVLLRDLEPGTDYEVTVSTL 398
Query: 1523 NGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPV 1582
GR P T + V + L V PTS+L+SW+ R YR+ + G P
Sbjct: 399 FGRSVGPATSLMARTDASVEQTLRPVILGPTSILLSWNL-VPEARGYRLEWRRETGLEPP 457
Query: 1583 QEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVT 1642
Q+ +P + + GL+PG +Y +T+Y + + + + + + +Q T
Sbjct: 458 QKVVLPSDVTRYQLDGLQPGTEYRLTLYTLLEGHEVATPATVVPTGPELPVSPVTDLQAT 517
Query: 1643 DVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVS 1702
++ + V W P T YR+ ++ G +T QT ++ +Q + Y V
Sbjct: 518 ELPGQRVRVSWSPVPG-ATQYRIIV--RSTQGVERTLVLPGSQTAFDLDDVQAGLSYTVR 574
Query: 1703 VYAQNPSGESQPLVQTAVTNIDRP---KGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSS 1759
V A+ E V T + P GL D +++AW P S +R+++S+
Sbjct: 575 VSARVGPREGSASVLTVRREPETPLAVPGLRVVVSDATRVRVAW-GPVPGASGFRISWST 633
Query: 1760 PEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPT-D 1818
PD ++ GL+PG+ Y V+V L E + T P
Sbjct: 634 GSGPESSQTLPPD--STATDITGLQPGTTYQVAVSVLRGREEGPAAVIVARTDPLGPVRT 691
Query: 1819 LKFTQVTPTSLSAQWT-PPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVAT 1877
+ TQ + +S++ WT P TGY RV+ GP K ++ +++ + GL T
Sbjct: 692 VHVTQASSSSVTITWTRVPGA--TGY--RVSWHSAHGPEKSQLVSGEATVAELDGLEPDT 747
Query: 1878 KYEVSVYALKDTLTSRPAQGVVTTL-ENVSPPRRARVTDATETTITISWRTKTETITGFQ 1936
+Y V V A + PA VV T E V R ++ +A+ + I+W T T ++
Sbjct: 748 EYTVHVRAHVAGVDGPPASVVVRTAPEPVGRVSRLQILNASSDVLRITWVGVTGA-TAYR 806
Query: 1937 VDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDA 1996
+ + G + + + S I GL+ G Y + + L + +PV I +T +A
Sbjct: 807 LAWGRSEGGPMRHQILPGNTDSAEIRGLEGGVSYSVRVTALVGDREGTPVSIVVTTPPEA 866
Query: 1997 P---SNLRFLATTPNSLLVSWQP-PRARITGYIIKYEKPGSPPREVVPRPRPGVTEATIT 2052
P L + +SL + W+P PRA+ G+++ ++ G + V P ++ +
Sbjct: 867 PPALGTLHVVQRGEHSLRLRWEPVPRAQ--GFLLHWQPEGGQEQSRVLGPE--LSSYHLD 922
Query: 2053 GLEPGTEYTI--YVIALKNNQKSEPLIGRKKTDELPQL------VTLPHPNLHGPEILDV 2104
GLEP T+Y + V+ S + R ++ +P + ++ L +
Sbjct: 923 GLEPATQYRVRLSVLGPAGEGPSAEVTARTESPRVPSIELRVVDTSIDSVTLAWTPVSRA 982
Query: 2105 PSTVQKTPFVTHPGYDT-GNGIQLPGTSGQQPSVG 2138
S + + PG + G+ LPG S Q G
Sbjct: 983 SSYILSWRPLRGPGQEVPGSPQTLPGISSSQRVTG 1017
Score = 194 bits (493), Expect = 9e-49
Identities = 212/841 (25%), Positives = 347/841 (41%), Gaps = 82/841 (9%)
Query: 1451 SPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRP-----REDRVPHSRNSIT 1505
+P + S+ ++ S V W A +TGY++++ P G+P +E VP S+
Sbjct: 234 APRDLVLSEPSSQSLRVQWTAASGPVTGYKVQYTPLTGLGQPLPSERQEVNVPAGETSVR 293
Query: 1506 LTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISW-DAPAV 1564
L L P TEY V+++AL + G T + +L + T SLL++W P
Sbjct: 294 LRGLRPLTEYQVTVIALYANSIGEAVSGTARTTALEGPELTIQNTTAHSLLVAWRSVPGA 353
Query: 1565 TVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKP 1624
T YR+T+ G Q+ PG S + L+PG DY +TV + GR PA+S
Sbjct: 354 TG--YRVTWRVLSGGPTQQQELGPGQGSVL-LRDLEPGTDYEVTVSTLFGRSVGPATS-- 408
Query: 1625 ISINYRTEIDKPSQMQVTDVQDNSISVKW--LPSSSPVTGYRVTTTPKNGPGPTKTKTAG 1682
+ RT+ ++ + SI + W +P + GYR+ + G P +
Sbjct: 409 --LMARTDASVEQTLRPVILGPTSILLSWNLVPEAR---GYRLEWRRETGLEPPQKVVLP 463
Query: 1683 PDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKG----LAFTDVDVDS 1738
D T ++GLQP EY +++Y E T + P L T++
Sbjct: 464 SDVTRYQLDGLQPGTEYRLTLYTLLEGHEVATPATVVPTGPELPVSPVTDLQATELPGQR 523
Query: 1739 IKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHD 1798
++++W SP ++YR+ S + G+ P G + +L ++ G YTV V A
Sbjct: 524 VRVSW-SPVPGATQYRIIVRSTQ-GVERTLVLP-GSQTAFDLDDVQAGLSYTVRVSARVG 580
Query: 1799 DMESQPLIGT----QSTAIPAPTDLKFTQVTPTSLSAQWTP-PNVQLTGYRVRVTPKEKT 1853
E + T T + P L+ T + W P P +G+R+ + +
Sbjct: 581 PREGSASVLTVRREPETPLAVP-GLRVVVSDATRVRVAWGPVPGA--SGFRISWSTG--S 635
Query: 1854 GPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARV 1913
GP L PDS++ ++GL T Y+V+V L+ PA +V + + P R V
Sbjct: 636 GPESSQTLPPDSTATDITGLQPGTTYQVAVSVLRGR-EEGPAAVIVARTDPLGPVRTVHV 694
Query: 1914 TDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIY 1973
T A+ +++TI+W T+ TG++V A+G Q + + + GL+P T+Y ++
Sbjct: 695 TQASSSSVTITW-TRVPGATGYRVSWHSAHGPEKSQ-LVSGEATVAELDGLEPDTEYTVH 752
Query: 1974 LYTLN---DNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEK 2030
+ D +S VV A + S L+ L + + L ++W +
Sbjct: 753 VRAHVAGVDGPPASVVVRTAPEPVGRVSRLQILNASSDVLRITWVGVTGATAYRLAWGRS 812
Query: 2031 PGSPPREVVPRPRPGVTE-ATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELPQLV 2089
G P R + PG T+ A I GLE G Y++ V AL +++ P+ +V
Sbjct: 813 EGGPMRHQI---LPGNTDSAEIRGLEGGVSYSVRVTALVGDREGTPV---------SIVV 860
Query: 2090 TLPHPNLHGPEILDVPSTVQKTPFVTHPGYDTGNGIQLPGTSG----QQPSVGQQ---MI 2142
T P P L VQ+ ++ +P G QP GQ+ ++
Sbjct: 861 TTPP---EAPPALGTLHVVQRGEHSLRLRWEP-----VPRAQGFLLHWQPEGGQEQSRVL 912
Query: 2143 FEEHGFRRTTPPTTATPIRHRPRPYPPNVGEEIQIGHIPREDVDYHLY-PHGPGLNPNAS 2201
E AT R R P G P +V P P +
Sbjct: 913 GPELSSYHLDGLEPATQYRVRLSVLGP-------AGEGPSAEVTARTESPRVPSIELRVV 965
Query: 2202 TGQEALSQTTISWAPFQDTSEYIISCHPV---GTDEEPLQFRVPGTSTSATLTGLTRGAT 2258
++ T++W P S YI+S P+ G + +PG S+S +TGL G +
Sbjct: 966 --DTSIDSVTLAWTPVSRASSYILSWRPLRGPGQEVPGSPQTLPGISSSQRVTGLEPGVS 1023
Query: 2259 Y 2259
Y
Sbjct: 1024 Y 1024
Score = 182 bits (463), Expect = 3e-45
Identities = 211/856 (24%), Positives = 366/856 (42%), Gaps = 81/856 (9%)
Query: 607 SSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGR-----WKEATIPG 661
S+S P ++ ++E SQ S +QW A ++ Y +++ P +G+ +E +P
Sbjct: 231 STSAPRDLVLSEPSSQ--SLRVQWTAAS-GPVTGYKVQYTPLTGLGQPLPSERQEVNVPA 287
Query: 662 HLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPL 721
S ++GL+P Y+ +I++ E TT+ P
Sbjct: 288 GETSVRLRGLRPLTEYQVTVIALYANSIGEAVSGTARTTALEGP---------------- 331
Query: 722 VATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLL 781
++ TA S +V+W S +G+RV + + G Q +L SV + DL
Sbjct: 332 ---ELTIQNTTAHSLLVAWRSVPG-ATGYRVTWRVL-SGGPTQQQELGPGQGSVLLRDLE 386
Query: 782 PGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQV--DDTSIVVRWSR-PQAPI 838
PG Y V V + +S+ +TS DA + T+ V TSI++ W+ P+A
Sbjct: 387 PGTDYEVTVSTLF---GRSVGPATSLMARTDASVEQTLRPVILGPTSILLSWNLVPEA-- 441
Query: 839 TGYRIVYSPSVE-GSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQE-STPVVIQQ 896
GYR+ + ++ LP L LQPG +Y +T+Y + E E +TP +
Sbjct: 442 RGYRLEWRRETGLEPPQKVVLPSDVTRYQLDGLQPGTEYRLTLYTLLEGHEVATPATVVP 501
Query: 897 ETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPI 956
P S DLQ E+ +V + W+P A T YR+ ++ E LP
Sbjct: 502 TGPELPVSPVT----DLQATELPGQRVRVSWSPVPGA-TQYRI-IVRSTQGVERTLVLPG 555
Query: 957 SRNTFAEVTGLSPGVTYYFKVFAVSHGRESK----PLTAQQTTKLDAPTNLQFVNETDST 1012
S+ F ++ + G++Y +V A RE + + T L P L+ V +
Sbjct: 556 SQTAF-DLDDVQAGLSYTVRVSARVGPREGSASVLTVRREPETPLAVP-GLRVVVSDATR 613
Query: 1013 VLVRWTP-PRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKG 1071
V V W P P A +G+R++ T G + P + + LQP + Y V++ ++G
Sbjct: 614 VRVAWGPVPGA--SGFRISWS-TGSGPESSQTLPPDSTATDITGLQPGTTYQVAVSVLRG 670
Query: 1072 NQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAP-RIGFKLGVRPSQGGEAPRE 1130
+E P A V T G + T+ + +++ ITWT P G+++ + G E +
Sbjct: 671 REEGPAAVIVARTDPLGPVRTVHVTQASSSSVTITWTRVPGATGYRVSWHSAHGPEKSQL 730
Query: 1131 VTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAP----IVNKVVTPLSPPTNLHLEANP 1186
V+ ++ + GL P E YT+ V D P +V P+ + L + N
Sbjct: 731 VSGEATVAELDGLEPDTE--YTVHVRAHVAGVDGPPASVVVRTAPEPVGRVSRLQI-LNA 787
Query: 1187 DTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVS 1246
+ VL ++W T T YR+ + G G +++ + S L G+ Y+V
Sbjct: 788 SSDVLRITWVGVT--GATAYRLAWGRSEG--GPMRHQILPGNTDSAEIRGLEGGVSYSVR 843
Query: 1247 VYTVKDDKESVPISDTII--PEV-PQLTDLSFVDITDSSIGLRWTPLNSSTIIGYRITVV 1303
V + D+E P+S + PE P L L V + S+ LRW P+ + G+ +
Sbjct: 844 VTALVGDREGTPVSIVVTTPPEAPPALGTLHVVQRGEHSLRLRWEPVPRAQ--GFLLH-- 899
Query: 1304 AAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAVP--PP 1361
EG + + Y + GLEP Y + + L GE +T +T P P
Sbjct: 900 WQPEGGQEQSRVLGPELSSYHLDGLEPATQYRVRLSVLGPAGEGPSAEVTARTESPRVPS 959
Query: 1362 TDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVK---NEEDVAELSISPSDNAVVLTN 1418
+LR + D++ + W P +++++ + P++ E + ++ ++ +T
Sbjct: 960 IELRVVDTSIDSVTLAWTPVSR--ASSYILSWRPLRGPGQEVPGSPQTLPGISSSQRVTG 1017
Query: 1419 LLPGTEYVVSVSSVYE 1434
L PG Y+ S++ V +
Sbjct: 1018 LEPGVSYIFSLTPVLD 1033
Score = 177 bits (449), Expect = 1e-43
Identities = 210/854 (24%), Positives = 367/854 (42%), Gaps = 76/854 (8%)
Query: 808 TTAPD----APPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSP------SVEGSSTELN 857
T PD AP D + + S+ V+W+ P+TGY++ Y+P + E+N
Sbjct: 225 TRPPDDSTSAPRDLVLSEPSSQSLRVQWTAASGPVTGYKVQYTPLTGLGQPLPSERQEVN 284
Query: 858 LPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVE 917
+P SV L L+P +Y +T+ A+ N I + +GT R+ + P +L
Sbjct: 285 VPAGETSVRLRGLRPLTEYQVTVIALYANS------IGEAVSGTARTTALEGP-ELTIQN 337
Query: 918 VTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKV 977
T + + W A TGYRV ++ Q L + + + L PG Y V
Sbjct: 338 TTAHSLLVAWRSVPGA-TGYRVTWRVLSGGPTQQQELGPGQGSVL-LRDLEPGTDYEVTV 395
Query: 978 FAVSHGRESKPLTAQQT-TKLDAPTNLQFVNETDSTVLVRWT-PPRAQITGYRLTVGLTR 1035
+ GR P T+ T L+ V +++L+ W P A+ GYRL
Sbjct: 396 STL-FGRSVGPATSLMARTDASVEQTLRPVILGPTSILLSWNLVPEAR--GYRLEWRRET 452
Query: 1036 RGQPRQYNVGPS-VSKYPLRNLQPASEYTVSLVAI-KGNQESPKATGVFTTLQ-PGSSIP 1092
+P Q V PS V++Y L LQP +EY ++L + +G++ + AT V T + P S +
Sbjct: 453 GLEPPQKVVLPSDVTRYQLDGLQPGTEYRLTLYTLLEGHEVATPATVVPTGPELPVSPVT 512
Query: 1093 PYN-TEVTETTIVITWTPAP-RIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYV 1150
TE+ + ++W+P P +++ VR +QG E + + + + G+ Y
Sbjct: 513 DLQATELPGQRVRVSWSPVPGATQYRIIVRSTQGVERTLVLPGSQTAFDLDDVQAGLSYT 572
Query: 1151 YTIQVL---RDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYR 1207
+ R+G + + TPL+ P L + + T V V+W P +G+R
Sbjct: 573 VRVSARVGPREGSASVLTVRREPETPLAVP-GLRVVVSDATRV-RVAW--GPVPGASGFR 628
Query: 1208 ITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPEV 1267
I+ + +G + + + + D ++ L PG Y V+V ++ +E + I+
Sbjct: 629 ISWSTGSGPESS---QTLPPDSTATDITGLQPGTTYQVAVSVLRGREEGP--AAVIVART 683
Query: 1268 PQLTDLSFVDITD---SSIGLRWTPLNSSTIIGYRITVVAAGEGIPIFEDFVDSSVGYYT 1324
L + V +T SS+ + WT + +T GYR++ +A P V
Sbjct: 684 DPLGPVRTVHVTQASSSSVTITWTRVPGAT--GYRVSWHSAHG--PEKSQLVSGEATVAE 739
Query: 1325 VTGLEPGIDYDISVITLINGGESAPTTLTQQTAVPPP---TDLRFTNIGPDTMRVTWAPP 1381
+ GLEP +Y + V + G + P ++ +TA P + L+ N D +R+TW
Sbjct: 740 LDGLEPDTEYTVHVRAHVAGVDGPPASVVVRTAPEPVGRVSRLQILNASSDVLRITW--- 796
Query: 1382 PSIDLTNFLV-RYSPVKNEEDVAELSISPSD-NAVVLTNLLPGTEYVVSVSSVYEQHEST 1439
+ +T R + ++E I P + ++ + L G Y V V+++ E T
Sbjct: 797 --VGVTGATAYRLAWGRSEGGPMRHQILPGNTDSAEIRGLEGGVSYSVRVTALVGDREGT 854
Query: 1440 PLRGRQKTGLDSPTGIDFSDITA---NSFTVHWI-APRATITGYRIRHHPEHFSGRPRED 1495
P+ T ++P + + +S + W PRA G+ + PE G+ +
Sbjct: 855 PVSIVVTTPPEAPPALGTLHVVQRGEHSLRLRWEPVPRAQ--GFLLHWQPE--GGQEQSR 910
Query: 1496 RVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPR----DLEVVAAT 1551
+ +S L L P T+Y V + L E P + + ++ PR +L VV +
Sbjct: 911 VLGPELSSYHLDGLEPATQYRVRLSVLGPAGEGPS--AEVTARTESPRVPSIELRVVDTS 968
Query: 1552 PTSLLISWDAPAVTVRYYRITYGETGGNS---PVQEFTVPGSKSTATISGLKPGVDYTIT 1608
S+ ++W P Y +++ G P T+PG S+ ++GL+PGV Y +
Sbjct: 969 IDSVTLAW-TPVSRASSYILSWRPLRGPGQEVPGSPQTLPGISSSQRVTGLEPGVSYIFS 1027
Query: 1609 VYAVTGRGDSPASS 1622
+ V P +S
Sbjct: 1028 LTPVLDGVRGPEAS 1041
Score = 160 bits (405), Expect = 1e-38
Identities = 184/729 (25%), Positives = 293/729 (40%), Gaps = 67/729 (9%)
Query: 562 QDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQPLQTYPSSSGPVEVFITETPS 621
+D E GT Y++ S +GR +G +T S VE +
Sbjct: 383 RDLEPGTDYEVTVST------------LFGRSVGPATSLMARTDAS----VEQTLRPVIL 426
Query: 622 QPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQL 681
P S + WN + Y L WR + + ++ +P + Y + GL+PG Y L
Sbjct: 427 GPTSILLSWNLVPEAR--GYRLEWRRETGLEPPQKVVLPSDVTRYQLDGLQPGTEYRLTL 484
Query: 682 ISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWV 741
++ + GH+ +TP T TG P SP+ T TE+ VSW
Sbjct: 485 YTLLE-GHE-----------VATPATV-VPTGPELPVSPV--TDLQATELPGQRVRVSW- 528
Query: 742 SASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQI--SEDGEQ 799
S + +R+ S +G E + L LP + T+ ++ D+ G Y V V +G
Sbjct: 529 SPVPGATQYRIIVR-STQGVE-RTLVLPGSQTAFDLDDVQAGLSYTVRVSARVGPREGSA 586
Query: 800 SLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLP 859
S++ + P A P V D T + V W P +G+RI +S G + LP
Sbjct: 587 SVLTVRREPETPLAVPGLRVVVSDATRVRVAWG-PVPGASGFRISWSTG-SGPESSQTLP 644
Query: 860 ETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVT 919
+ + ++ LQPG Y + + + +E VI R+D + R + + +
Sbjct: 645 PDSTATDITGLQPGTTYQVAVSVLRGREEGPAAVI------VARTDPLGPVRTVHVTQAS 698
Query: 920 DVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFA 979
VTI WT A TGYRV + G +L T AE+ GL P Y V A
Sbjct: 699 SSSVTITWTRVPGA-TGYRVSWHSAH--GPEKSQLVSGEATVAELDGLEPDTEYTVHVRA 755
Query: 980 VSHGRESKPLTAQQTT---KLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRR 1036
G + P + T + + LQ +N + + + W T YRL G +
Sbjct: 756 HVAGVDGPPASVVVRTAPEPVGRVSRLQILNASSDVLRITWVGVTG-ATAYRLAWGRSEG 814
Query: 1037 GQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNT 1096
G R + + +R L+ Y+V + A+ G++E + V TT P + P T
Sbjct: 815 GPMRHQILPGNTDSAEIRGLEGGVSYSVRVTALVGDREGTPVSIVVTT--PPEAPPALGT 872
Query: 1097 ----EVTETTIVITWTPAPRI-GFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVY 1151
+ E ++ + W P PR GF L +P G E R + + S + GL P +Y
Sbjct: 873 LHVVQRGEHSLRLRWEPVPRAQGFLLHWQPEGGQEQSRVLGPELSSYHLDGLEPATQYRV 932
Query: 1152 TIQVLRD-GQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITT 1210
+ VL G+ A + + +P P L + DT + +V+ + + Y ++
Sbjct: 933 RLSVLGPAGEGPSAEVTARTESPRVPSIELRV---VDTSIDSVTLAWTPVSRASSYILSW 989
Query: 1211 TPTN--GQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPEVP 1268
P GQ+ + + SS L PG+ Y S+ V D S T P P
Sbjct: 990 RPLRGPGQEVPGSPQTLPGISSSQRVTGLEPGVSYIFSLTPVLDGVRGPEASVTQTPVCP 1049
Query: 1269 Q-LTDLSFV 1276
+ L D+ F+
Sbjct: 1050 RGLADVVFL 1058
Score = 119 bits (298), Expect = 4e-26
Identities = 127/480 (26%), Positives = 204/480 (42%), Gaps = 43/480 (8%)
Query: 1804 PLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGP-----MKE 1858
P+ + AP DL ++ + SL QWT + +TGY+V+ TP G +E
Sbjct: 223 PVTRPPDDSTSAPRDLVLSEPSSQSLRVQWTAASGPVTGYKVQYTPLTGLGQPLPSERQE 282
Query: 1859 INLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATE 1918
+N+ +SV + GL T+Y+V+V AL G T P + + T
Sbjct: 283 VNVPAGETSVRLRGLRPLTEYQVTVIALYANSIGEAVSGTARTTALEGP--ELTIQNTTA 340
Query: 1919 TTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLN 1978
++ ++WR+ TG++V +G Q+ + P S + L+PGTDY++ + TL
Sbjct: 341 HSLLVAWRS-VPGATGYRVTWRVLSGGPTQQQELGPGQGSVLLRDLEPGTDYEVTVSTLF 399
Query: 1979 DNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQ-PPRARITGYIIKYEKPGS--PP 2035
+ + A T LR + P S+L+SW P AR GY +++ + PP
Sbjct: 400 GRSVGPATSLMARTDASVEQTLRPVILGPTSILLSWNLVPEAR--GYRLEWRRETGLEPP 457
Query: 2036 REVVPRPRPGVTEATITGLEPGTEY--TIYVIALKNNQKSEPLIGRKKTDELPQLVTLPH 2093
++VV VT + GL+PGTEY T+Y + L+ ++ + P ELP P
Sbjct: 458 QKVVLPS--DVTRYQLDGLQPGTEYRLTLYTL-LEGHEVATPATVVPTGPELP---VSPV 511
Query: 2094 PNLHGPEILDVPSTVQKTPFVTHPGYDTGNGIQLPGTSGQQPSV---GQQMIFEEHGFRR 2150
+L E+ V +P PG T I + T G + ++ G Q F+ +
Sbjct: 512 TDLQATELPGQRVRVSWSPV---PGA-TQYRIIVRSTQGVERTLVLPGSQTAFDLDDVQA 567
Query: 2151 TTPPTTATPIRHRPRPYPPNVGEEIQIGHIPREDVDYHLYPHGPGLNPNASTGQEALSQT 2210
T R PR +V + RE P P P ++
Sbjct: 568 GLSYTVRVSARVGPREGSASVLT------VRRE-------PETPLAVPGLRVVVSDATRV 614
Query: 2211 TISWAPFQDTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQ 2270
++W P S + IS G+ E Q +P ST+ +TGL G TY + V L+ ++
Sbjct: 615 RVAWGPVPGASGFRISWS-TGSGPESSQ-TLPPDSTATDITGLQPGTTYQVAVSVLRGRE 672
Score = 117 bits (294), Expect = 1e-25
Identities = 155/681 (22%), Positives = 264/681 (38%), Gaps = 70/681 (10%)
Query: 1612 VTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKN 1671
V+ R + A P++ P + +++ S+ V+W +S PVTGY+V TP
Sbjct: 211 VSRRVCTTAGGVPVTRPPDDSTSAPRDLVLSEPSSQSLRVQWTAASGPVTGYKVQYTPLT 270
Query: 1672 G-----PGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRP 1726
G P + +T + + GL+P EY V+V A + + + TA T
Sbjct: 271 GLGQPLPSERQEVNVPAGETSVRLRGLRPLTEYQVTVIALYANSIGEAVSGTARTTALEG 330
Query: 1727 KGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDG---IHELFPAPDGEEDTAELQGL 1783
L + S+ +AW S G + YRVT+ G EL P + + L+ L
Sbjct: 331 PELTIQNTTAHSLLVAWRSVPG-ATGYRVTWRVLSGGPTQQQELGPG----QGSVLLRDL 385
Query: 1784 RPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQ------VTPTSLSAQWTPPN 1837
PG++Y V+V L +T++ A TD Q + PTS+ W
Sbjct: 386 EPGTDYEVTVSTLFGRSVG------PATSLMARTDASVEQTLRPVILGPTSILLSWNLV- 438
Query: 1838 VQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYA-LKDTLTSRPAQ 1896
+ GYR+ + P +++ L D + + GL T+Y +++Y L+ + PA
Sbjct: 439 PEARGYRLEWRRETGLEPPQKVVLPSDVTRYQLDGLQPGTEYRLTLYTLLEGHEVATPAT 498
Query: 1897 GVVTTLE-NVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRT--IK 1953
V T E VSP + T+ + +SW + G + ++RT +
Sbjct: 499 VVPTGPELPVSPVTDLQATELPGQRVRVSW----SPVPGATQYRIIVRSTQGVERTLVLP 554
Query: 1954 PDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAP---SNLRFLATTPNSL 2010
++ + +Q G Y + + S V+ + P LR + + +
Sbjct: 555 GSQTAFDLDDVQAGLSYTVRVSARVGPREGSASVLTVRREPETPLAVPGLRVVVSDATRV 614
Query: 2011 LVSWQP-PRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKN 2069
V+W P P A +G+ I + GS P P P T ITGL+PGT Y + V L+
Sbjct: 615 RVAWGPVPGA--SGFRISW-STGSGPESSQTLP-PDSTATDITGLQPGTTYQVAVSVLRG 670
Query: 2070 NQKSEPLIGRKKTDELPQLVTLPHPNLHGPEILDVPSTVQKTPFVTHPGYDTGNGIQLPG 2129
++ + +TD L + T+ + S+ + PG TG +
Sbjct: 671 REEGPAAVIVARTDPLGPVRTV--------HVTQASSSSVTITWTRVPG-ATGYRVSWHS 721
Query: 2130 TSGQQPS---VGQQMIFEEHGFRRTTPPTTATPIRHRPRPYPPNVGEEIQIGHIPREDVD 2186
G + S G+ + E G T Y +V + P V
Sbjct: 722 AHGPEKSQLVSGEATVAELDGLEPDT-------------EYTVHVRAHVAGVDGPPASVV 768
Query: 2187 YHLYPHGPGLNPNASTGQEALSQTTISWAPFQDTSEYIISCHPVGTDEEPLQFRV-PGTS 2245
P G + I+W + Y ++ ++ P++ ++ PG +
Sbjct: 769 VRTAPEPVGRVSRLQILNASSDVLRITWVGVTGATAYRLAWG--RSEGGPMRHQILPGNT 826
Query: 2246 TSATLTGLTRGATYNIIVEAL 2266
SA + GL G +Y++ V AL
Sbjct: 827 DSAEIRGLEGGVSYSVRVTAL 847
>gi|55743096 collagen, type XIV, alpha 1 [Homo sapiens]
Length = 1796
Score = 211 bits (537), Expect = 7e-54
Identities = 246/1013 (24%), Positives = 420/1013 (41%), Gaps = 134/1013 (13%)
Query: 907 VPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTG 966
V P L++ ++ + I W P GY++ V P + G+ Q + T A + G
Sbjct: 30 VAPPTRLRYNVISHDSIQISWKAPRGKFGGYKLLVTPTS-GGKTNQLNLQNTATKAIIQG 88
Query: 967 LSPGVTYYFKVFAVSHGRESKPLTAQ----------------------QTTKLDAPTNLQ 1004
L P Y ++ A + +ESKP Q ++ +P ++
Sbjct: 89 LMPDQNYTVQIIAYNKDKESKPAQGQFRIKDLEKRKDPKPRVKVVDRGNGSRPSSPEEVK 148
Query: 1005 FVNET----DSTVLV--RWTPPRAQ-----------ITGYRLTVGLTRRGQPRQYNVGPS 1047
FV +T D +LV W+ R +T + + TR G QY+ P
Sbjct: 149 FVCQTPAIADIVILVDGSWSIGRFNFRLVRHFLENLVTAFDVGSEKTRIGLA-QYSGDPR 207
Query: 1048 VSKY------------PLRNLQPASEYTVSLVAIK---GNQESPKA---TGV------FT 1083
+ + +RNL T++ +A+ N P+A TGV T
Sbjct: 208 IEWHLNAFSTKDEVIEAVRNLPYKGGNTLTGLALNYIFENSFKPEAGSRTGVSKIGILIT 267
Query: 1084 TLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGL 1143
+ I P + + E+ + + F +GV+ + E +E+ S+ S V +
Sbjct: 268 DGKSQDDIIPPSRNLRESGVEL---------FAIGVKNADVNEL-QEIASEPDSTHVYNV 317
Query: 1144 TPGVEYVYTI------QVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWER 1197
+ ++T+ + +E+D I PPT L + + V+W
Sbjct: 318 AE-FDLMHTVVESLTRTLCSRVEEQDREIKASAHAITGPPTEL-ITSEVTARSFMVNWTH 375
Query: 1198 STTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESV 1257
+ ++ YR+ PT G G E VV SS NL EY ++V+ + S
Sbjct: 376 APG-NVEKYRVVYYPTRG--GKPDEVVVDGTVSSTVLKNLMSLTEYQIAVFAIYAHTASE 432
Query: 1258 PISDTIIP-EVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIFEDFV 1316
+ T +P +DL D+T++S+ ++W + ++ GY I EG+ D
Sbjct: 433 GLRGTETTLALPMASDLLLYDVTENSMRVKWDAVPGAS--GYLILYAPLTEGLA--GDEK 488
Query: 1317 DSSVGY----YTVTGLEPGIDYDISVITLINGGESAPTTLTQQT-AVPPPTDLRFTNIGP 1371
+ +G ++GL P +Y ++V + S P T + T A+ PP +LR +N+G
Sbjct: 489 EMKIGETHTDIELSGLLPNTEYTVTVYAMFGEEASDPVTGQETTLALSPPRNLRISNVGS 548
Query: 1372 DTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSS 1431
++ R+TW P S + + + Y+ E + E+ + P L L P TEY +++ S
Sbjct: 549 NSARLTW-DPTSRQINGYRIVYNNADGTE-INEVEVDPI-TTFPLKGLTPLTEYTIAIFS 605
Query: 1432 VYEQHESTPLRGRQKTG-LDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSG 1490
+Y++ +S PL G T + + ++ ++T +SF V W A +++ P + G
Sbjct: 606 IYDEGQSEPLTGVFTTEEVPAQQYLEIDEVTTDSFRVTWHPLSADEGLHKLMWIPV-YGG 664
Query: 1491 RPREDRVPHSRNSITLTNLTPGTEYVVSIVA-LNGREESPLLIGQQSTVSD--------- 1540
+ E + ++S + L PGTEY VS++A L+ ES ++ +T+
Sbjct: 665 KTEEVVLKEEQDSHVIEGLEPGTEYEVSLLAVLDDGSESEVVTAVGTTLDSFWTEPATTI 724
Query: 1541 VP------------RDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFT-- 1586
VP R+L V T +SL + WD V+ +R+TY G+ P +E
Sbjct: 725 VPTTSVTSVFQTGIRNLVVGDETTSSLRVKWDISDSDVQQFRVTYMTAQGD-PEEEVIGT 783
Query: 1587 --VPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDV 1644
VPGS++ + L P +Y +TV + G+ + S P P ++V++
Sbjct: 784 VMVPGSQNNLLLKPLLPDTEYKVTVTPIYTDGEGVSVSAP---GKTLPSSGPQNLRVSEE 840
Query: 1645 QDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVY 1704
N + + W P SSPV GYR+ P + PGPT G D + I L ++Y V ++
Sbjct: 841 WYNRLRITWDPPSSPVKGYRIVYKPVSVPGPTLETFVGADINTILITNLLSGMDYNVKIF 900
Query: 1705 AQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGI 1764
A SG S L T L V++ S+ W+ + + YRV S +D
Sbjct: 901 ASQASGFSDALTGMVKTLFLGVTNLQAKHVEMTSLCAHWQVHR-HATAYRVVIESLQDRQ 959
Query: 1765 HELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPT 1817
+ G GL+P SEY +SV ++E P + PT
Sbjct: 960 KQESTVGGGTTRHC-FYGLQPDSEYKISVYTKLQEIEG-PSVSIMEKTQSLPT 1010
Score = 208 bits (529), Expect = 6e-53
Identities = 169/651 (25%), Positives = 298/651 (45%), Gaps = 50/651 (7%)
Query: 1360 PPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNL 1419
PPT+L + + + V W P ++ + V Y P + + E+ + + ++ VL NL
Sbjct: 355 PPTELITSEVTARSFMVNWTHAPG-NVEKYRVVYYPTRGGKP-DEVVVDGTVSSTVLKNL 412
Query: 1420 LPGTEYVVSVSSVYEQHESTPLRGRQKT-GLDSPTGIDFSDITANSFTVHWIAPRATITG 1478
+ TEY ++V ++Y S LRG + T L + + D+T NS V W A +G
Sbjct: 413 MSLTEYQIAVFAIYAHTASEGLRGTETTLALPMASDLLLYDVTENSMRVKWDAVPGA-SG 471
Query: 1479 YRIRHHP--EHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQS 1536
Y I + P E +G +E ++ + I L+ L P TEY V++ A+ G E S + GQ++
Sbjct: 472 YLILYAPLTEGLAGDEKEMKIGETHTDIELSGLLPNTEYTVTVYAMFGEEASDPVTGQET 531
Query: 1537 TVS-DVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTAT 1595
T++ PR+L + S ++WD + + YRI Y G + E V +T
Sbjct: 532 TLALSPPRNLRISNVGSNSARLTWDPTSRQINGYRIVYNNADGTE-INEVEVDPI-TTFP 589
Query: 1596 ISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQ--MQVTDVQDNSISVKW 1653
+ GL P +YTI ++++ G S +P++ + TE + P+Q +++ +V +S V W
Sbjct: 590 LKGLTPLTEYTIAIFSIYDEGQS----EPLTGVFTTE-EVPAQQYLEIDEVTTDSFRVTW 644
Query: 1654 LPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQ 1713
P S+ +++ P G G T+ +Q IEGL+P EY VS+ A G
Sbjct: 645 HPLSADEGLHKLMWIPVYG-GKTEEVVLKEEQDSHVIEGLEPGTEYEVSLLAVLDDGSES 703
Query: 1714 PLVQTAVTNIDR----------------------PKGLAFTDVDVDSIKIAWESPQGQVS 1751
+V T +D + L D S+++ W+ V
Sbjct: 704 EVVTAVGTTLDSFWTEPATTIVPTTSVTSVFQTGIRNLVVGDETTSSLRVKWDISDSDVQ 763
Query: 1752 RYRVTYSS----PEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIG 1807
++RVTY + PE+ + P G ++ L+ L P +EY V+V ++ D E +
Sbjct: 764 QFRVTYMTAQGDPEEEVIGTVMVP-GSQNNLLLKPLLPDTEYKVTVTPIYTDGEGVSVSA 822
Query: 1808 TQSTAIPA--PTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDS 1865
T +P+ P +L+ ++ L W PP+ + GYR+ P GP E + D
Sbjct: 823 PGKT-LPSSGPQNLRVSEEWYNRLRITWDPPSSPVKGYRIVYKPVSVPGPTLETFVGADI 881
Query: 1866 SSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISW 1925
++++++ L+ Y V ++A + + S G+V TL +A+ + T++ W
Sbjct: 882 NTILITNLLSGMDYNVKIFASQASGFSDALTGMVKTLFLGVTNLQAKHVEM--TSLCAHW 939
Query: 1926 RTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYT 1976
+ T ++V + + T+ + GLQP ++YKI +YT
Sbjct: 940 QVHRHA-TAYRVVIESLQDRQKQESTVGGGTTRHCFYGLQPDSEYKISVYT 989
Score = 183 bits (465), Expect = 2e-45
Identities = 174/687 (25%), Positives = 291/687 (42%), Gaps = 54/687 (7%)
Query: 795 EDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSST 854
E+ ++ + S T P P + +V S +V W+ + YR+VY P+ G
Sbjct: 339 EEQDREIKASAHAITGP--PTELITSEVTARSFMVNWTHAPGNVEKYRVVYYPTRGGKPD 396
Query: 855 ELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQ 914
E+ + T +S L +L +Y I ++A+ + S + GT + +P DL
Sbjct: 397 EVVVDGTVSSTVLKNLMSLTEYQIAVFAIYAHTAS------EGLRGTETTLALPMASDLL 450
Query: 915 FVEVTDVKVTIMWTPPESAVTGYRVDVIPV--NLPGEHGQRLPISRNTFAEVTGLSPGVT 972
+VT+ + + W A +GY + P+ L G+ + +T E++GL P
Sbjct: 451 LYDVTENSMRVKWDAVPGA-SGYLILYAPLTEGLAGDEKEMKIGETHTDIELSGLLPNTE 509
Query: 973 YYFKVFAVSHGRESKPLTAQQTT-KLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTV 1031
Y V+A+ S P+T Q+TT L P NL+ N ++ + W P QI GYR+
Sbjct: 510 YTVTVYAMFGEEASDPVTGQETTLALSPPRNLRISNVGSNSARLTWDPTSRQINGYRIVY 569
Query: 1032 GLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSI 1091
+ + V P ++ +PL+ L P +EYT+++ +I +S TGVFTT + +
Sbjct: 570 NNADGTEINEVEVDP-ITTFPLKGLTPLTEYTIAIFSIYDEGQSEPLTGVFTTEEVPAQQ 628
Query: 1092 PPYNTEVTETTIVITWTP--APRIGFKLGVRPSQGGEAPREV-TSDSGSIVVSGLTPGVE 1148
EVT + +TW P A KL P GG+ V + S V+ GL PG E
Sbjct: 629 YLEIDEVTTDSFRVTWHPLSADEGLHKLMWIPVYGGKTEEVVLKEEQDSHVIEGLEPGTE 688
Query: 1149 Y-VYTIQVLRDGQERDAPIV---------NKVVTPLSPPTNLH----------LEANPDT 1188
Y V + VL DG E + + T + P T++ + + T
Sbjct: 689 YEVSLLAVLDDGSESEVVTAVGTTLDSFWTEPATTIVPTTSVTSVFQTGIRNLVVGDETT 748
Query: 1189 GVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEV-----VHADQSSCTFDNLSPGLEY 1243
L V W+ S + D+ +R+T QG+ EEV V Q++ L P EY
Sbjct: 749 SSLRVKWDISDS-DVQQFRVTYMTA---QGDPEEEVIGTVMVPGSQNNLLLKPLLPDTEY 804
Query: 1244 NVSVYTVKDDKESVPIS---DTIIPEVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGYRI 1300
V+V + D E V +S T+ PQ +L + + + + W P SS + GYRI
Sbjct: 805 KVTVTPIYTDGEGVSVSAPGKTLPSSGPQ--NLRVSEEWYNRLRITWDP-PSSPVKGYRI 861
Query: 1301 TVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAVPP 1360
P E FV + + +T L G+DY++ + G S T +T
Sbjct: 862 VYKPVSVPGPTLETFVGADINTILITNLLSGMDYNVKIFASQASGFSDALTGMVKTLFLG 921
Query: 1361 PTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLL 1420
T+L+ ++ ++ W ++ + ++ E ++ L
Sbjct: 922 VTNLQAKHVEMTSLCAHWQVHRHATAYRVVIESLQDRQKQ---ESTVGGGTTRHCFYGLQ 978
Query: 1421 PGTEYVVSVSSVYEQHESTPLRGRQKT 1447
P +EY +SV + ++ E + +KT
Sbjct: 979 PDSEYKISVYTKLQEIEGPSVSIMEKT 1005
Score = 183 bits (464), Expect = 2e-45
Identities = 170/701 (24%), Positives = 295/701 (42%), Gaps = 71/701 (10%)
Query: 1430 SSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFS 1489
S V EQ TG PT + S++TA SF V+W + YR+ ++P
Sbjct: 336 SRVEEQDREIKASAHAITG--PPTELITSEVTARSFMVNWTHAPGNVEKYRVVYYPTR-G 392
Query: 1490 GRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVS-DVPRDLEVV 1548
G+P E V + +S L NL TEY +++ A+ S L G ++T++ + DL +
Sbjct: 393 GKPDEVVVDGTVSSTVLKNLMSLTEYQIAVFAIYAHTASEGLRGTETTLALPMASDLLLY 452
Query: 1549 AATPTSLLISWDA----PAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVD 1604
T S+ + WDA + Y +T G G +E + + + +SGL P +
Sbjct: 453 DVTENSMRVKWDAVPGASGYLILYAPLTEGLAGDE---KEMKIGETHTDIELSGLLPNTE 509
Query: 1605 YTITVYAVTGRGDSPASSKPISINYRT-EIDKPSQMQVTDVQDNSISVKWLPSSSPVTGY 1663
YT+TVYA+ G +S P++ T + P +++++V NS + W P+S + GY
Sbjct: 510 YTVTVYAMFGE----EASDPVTGQETTLALSPPRNLRISNVGSNSARLTWDPTSRQINGY 565
Query: 1664 RVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTN- 1722
R+ N G + T ++GL P EY +++++ G+S+PL T
Sbjct: 566 RIVYN--NADGTEINEVEVDPITTFPLKGLTPLTEYTIAIFSIYDEGQSEPLTGVFTTEE 623
Query: 1723 IDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAP----------- 1771
+ + L +V DS ++ W S ++G+H+L P
Sbjct: 624 VPAQQYLEIDEVTTDSFRVTWHP------------LSADEGLHKLMWIPVYGGKTEEVVL 671
Query: 1772 DGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAI------PAPTDLKFTQVT 1825
E+D+ ++GL PG+EY VS++A+ DD ++ T + PA T + T VT
Sbjct: 672 KEEQDSHVIEGLEPGTEYEVSLLAVLDDGSESEVVTAVGTTLDSFWTEPATTIVPTTSVT 731
Query: 1826 P----------------TSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEIN--LAPDS-S 1866
+SL +W + + +RV + + I + P S +
Sbjct: 732 SVFQTGIRNLVVGDETTSSLRVKWDISDSDVQQFRVTYMTAQGDPEEEVIGTVMVPGSQN 791
Query: 1867 SVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWR 1926
++++ L+ T+Y+V+V + TL + S P+ RV++ + I+W
Sbjct: 792 NLLLKPLLPDTEYKVTVTPIYTDGEGVSVSAPGKTLPS-SGPQNLRVSEEWYNRLRITWD 850
Query: 1927 TKTETITGFQVDAVPANGQTPIQRT-IKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSP 1985
+ + G+++ P + P T + D+ + IT L G DY + ++ + S
Sbjct: 851 PPSSPVKGYRIVYKPVSVPGPTLETFVGADINTILITNLLSGMDYNVKIFASQASGFSDA 910
Query: 1986 VVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPG 2045
+ T +NL+ SL WQ R T Y + E ++ G
Sbjct: 911 LTGMVKTLFLGVTNLQAKHVEMTSLCAHWQVHR-HATAYRVVIESLQDRQKQ-ESTVGGG 968
Query: 2046 VTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELP 2086
T GL+P +EY I V + + +KT LP
Sbjct: 969 TTRHCFYGLQPDSEYKISVYTKLQEIEGPSVSIMEKTQSLP 1009
Score = 171 bits (434), Expect = 6e-42
Identities = 167/672 (24%), Positives = 288/672 (42%), Gaps = 57/672 (8%)
Query: 729 TEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIV 788
+E+TA SF+V+W A V +RV Y G +P + + T +S + +L+ +Y +
Sbjct: 362 SEVTARSFMVNWTHAPGNVEKYRVVY-YPTRGGKPDEVVVDGTVSSTVLKNLMSLTEYQI 420
Query: 789 NVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPS 848
V+ I + T T A D + V + S+ V+W +GY I+Y+P
Sbjct: 421 AVFAIYAHTASEGLRGTETTLALPMASDLLLYDVTENSMRVKWDAVPG-ASGYLILYAPL 479
Query: 849 VE---GSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSD 905
E G E+ + ET + LS L P +Y +T+YA+ + S PV Q+ T
Sbjct: 480 TEGLAGDEKEMKIGETHTDIELSGLLPNTEYTVTVYAMFGEEASDPVTGQETTL------ 533
Query: 906 TVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVT 965
+ PR+L+ V + W P + GYR ++ N G + + T +
Sbjct: 534 ALSPPRNLRISNVGSNSARLTWDPTSRQINGYR--IVYNNADGTEINEVEVDPITTFPLK 591
Query: 966 GLSPGVTYYFKVFAVSHGRESKPLTAQQTT-KLDAPTNLQFVNETDSTVLVRWTPPRAQI 1024
GL+P Y +F++ +S+PLT TT ++ A L+ T + V W P A
Sbjct: 592 GLTPLTEYTIAIFSIYDEGQSEPLTGVFTTEEVPAQQYLEIDEVTTDSFRVTWHPLSADE 651
Query: 1025 TGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAI-KGNQESPKATGVFT 1083
++L G+ + + + + L+P +EY VSL+A+ ES T V T
Sbjct: 652 GLHKLMWIPVYGGKTEEVVLKEEQDSHVIEGLEPGTEYEVSLLAVLDDGSESEVVTAVGT 711
Query: 1084 TL-----QPGSSIPPYNT---------------EVTETTIVITW--TPAPRIGFKLGVRP 1121
TL +P ++I P + + T +++ + W + + F++
Sbjct: 712 TLDSFWTEPATTIVPTTSVTSVFQTGIRNLVVGDETTSSLRVKWDISDSDVQQFRVTYMT 771
Query: 1122 SQGGEAPRE-------VTSDSGSIVVSGLTPGVEYVYTI-QVLRDGQERDAPIVNKVVTP 1173
+QG P E V ++++ L P EY T+ + DG+ K + P
Sbjct: 772 AQGD--PEEEVIGTVMVPGSQNNLLLKPLLPDTEYKVTVTPIYTDGEGVSVSAPGKTL-P 828
Query: 1174 LSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCT 1233
S P NL + + L ++W+ ++P + GYRI P + G +LE V AD ++
Sbjct: 829 SSGPQNLRV-SEEWYNRLRITWDPPSSP-VKGYRIVYKPVS-VPGPTLETFVGADINTIL 885
Query: 1234 FDNLSPGLEYNVSVYTVKDDKESVPISDTIIPEVPQLTDLSFVDITDSSIGLRWTPLNSS 1293
NL G++YNV ++ + S ++ + +T+L + +S+ W +
Sbjct: 886 ITNLLSGMDYNVKIFASQASGFSDALTGMVKTLFLGVTNLQAKHVEMTSLCAHWQVHRHA 945
Query: 1294 TIIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTL- 1352
T YR+ V+ + + E V + GL+P +Y ISV T + E ++
Sbjct: 946 T--AYRV-VIESLQDRQKQESTVGGGTTRHCFYGLQPDSEYKISVYTKLQEIEGPSVSIM 1002
Query: 1353 --TQQTAVPPPT 1362
TQ PPT
Sbjct: 1003 EKTQSLPTRPPT 1014
Score = 100 bits (248), Expect = 2e-20
Identities = 130/581 (22%), Positives = 232/581 (39%), Gaps = 53/581 (9%)
Query: 624 NSHPIQWNAPQPSHISKYILRWRP--KNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQL 681
NS ++W+A + S Y++ + P + G KE I + GL P Y
Sbjct: 457 NSMRVKWDAVPGA--SGYLILYAPLTEGLAGDEKEMKIGETHTDIELSGLLPNTEYT--- 511
Query: 682 ISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWV 741
VT + S PVT T +P L ++ + ++S ++W
Sbjct: 512 ----------VTVYAMFGEEASDPVTGQETTLALSPPRNL-----RISNVGSNSARLTWD 556
Query: 742 SASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSL 801
S ++G+R+ Y + +G E +++ T+ + L P +Y + ++ I ++G+
Sbjct: 557 PTSRQINGYRIVYN-NADGTEINEVEV-DPITTFPLKGLTPLTEYTIAIFSIYDEGQSEP 614
Query: 802 ILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPET 861
+ T A +D+V S V W A +++++ P G + E+ L E
Sbjct: 615 LTGVFTTEEVPAQQYLEIDEVTTDSFRVTWHPLSADEGLHKLMWIPVYGGKTEEVVLKEE 674
Query: 862 ANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETT-----GTPRSDTVPSP------ 910
+S + L+PG +Y +++ AV ++ + VV TT P + VP+
Sbjct: 675 QDSHVIEGLEPGTEYEVSLLAVLDDGSESEVVTAVGTTLDSFWTEPATTIVPTTSVTSVF 734
Query: 911 ----RDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEH----GQRLPISRNTFA 962
R+L + T + + W +S V +RV + E +P S+N
Sbjct: 735 QTGIRNLVVGDETTSSLRVKWDISDSDVQQFRVTYMTAQGDPEEEVIGTVMVPGSQNNLL 794
Query: 963 EVTGLSPGVTYYFKVFAVSHGRESKPLTAQ-QTTKLDAPTNLQFVNETDSTVLVRWTPPR 1021
+ L P Y V + E ++A +T P NL+ E + + + W PP
Sbjct: 795 -LKPLLPDTEYKVTVTPIYTDGEGVSVSAPGKTLPSSGPQNLRVSEEWYNRLRITWDPPS 853
Query: 1022 AQITGYRLTV-GLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG 1080
+ + GYR+ ++ G + VG ++ + NL +Y V + A + + S TG
Sbjct: 854 SPVKGYRIVYKPVSVPGPTLETFVGADINTILITNLLSGMDYNVKIFASQASGFSDALTG 913
Query: 1081 VFTTLQPG-SSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSI- 1138
+ TL G +++ + E+ T++ W V S +E T G+
Sbjct: 914 MVKTLFLGVTNLQAKHVEM--TSLCAHWQVHRHATAYRVVIESLQDRQKQESTVGGGTTR 971
Query: 1139 -VVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPT 1178
GL P E Y I V QE + P V+ + S PT
Sbjct: 972 HCFYGLQPDSE--YKISVYTKLQEIEGPSVSIMEKTQSLPT 1010
Score = 53.1 bits (126), Expect = 3e-06
Identities = 31/106 (29%), Positives = 51/106 (48%), Gaps = 4/106 (3%)
Query: 1813 IPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSG 1872
+ PT L++ ++ S+ W P + GY++ VTP G ++NL ++ ++ G
Sbjct: 30 VAPPTRLRYNVISHDSIQISWKAPRGKFGGYKLLVTPTSG-GKTNQLNLQNTATKAIIQG 88
Query: 1873 LMVATKYEVSVYALKDTLTSRPAQGV--VTTLENVSPPR-RARVTD 1915
LM Y V + A S+PAQG + LE P+ R +V D
Sbjct: 89 LMPDQNYTVQIIAYNKDKESKPAQGQFRIKDLEKRKDPKPRVKVVD 134
Score = 50.1 bits (118), Expect = 3e-05
Identities = 21/70 (30%), Positives = 36/70 (51%)
Query: 822 VDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIY 881
+ SI + W P+ GY+++ +P+ G + +LNL TA + L P Y + I
Sbjct: 41 ISHDSIQISWKAPRGKFGGYKLLVTPTSGGKTNQLNLQNTATKAIIQGLMPDQNYTVQII 100
Query: 882 AVEENQESTP 891
A +++ES P
Sbjct: 101 AYNKDKESKP 110
Score = 48.1 bits (113), Expect = 1e-04
Identities = 33/125 (26%), Positives = 59/125 (47%), Gaps = 8/125 (6%)
Query: 1997 PSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEP 2056
P+ LR+ + +S+ +SW+ PR + GY + P S + + T+A I GL P
Sbjct: 33 PTRLRYNVISHDSIQISWKAPRGKFGGYKLLVT-PTSGGKTNQLNLQNTATKAIIQGLMP 91
Query: 2057 GTEYTIYVIALKNNQKSEPLIGR-------KKTDELPQLVTLPHPNLHGPEILDVPSTVQ 2109
YT+ +IA +++S+P G+ K+ D P++ + N P + V
Sbjct: 92 DQNYTVQIIAYNKDKESKPAQGQFRIKDLEKRKDPKPRVKVVDRGNGSRPSSPEEVKFVC 151
Query: 2110 KTPFV 2114
+TP +
Sbjct: 152 QTPAI 156
Score = 45.8 bits (107), Expect = 5e-04
Identities = 23/83 (27%), Positives = 39/83 (46%), Gaps = 1/83 (1%)
Query: 1632 EIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIE 1691
++ P++++ + +SI + W GY++ TP +G G T T+ I+
Sbjct: 29 QVAPPTRLRYNVISHDSIQISWKAPRGKFGGYKLLVTPTSG-GKTNQLNLQNTATKAIIQ 87
Query: 1692 GLQPTVEYVVSVYAQNPSGESQP 1714
GL P Y V + A N ES+P
Sbjct: 88 GLMPDQNYTVQIIAYNKDKESKP 110
Score = 41.6 bits (96), Expect = 0.010
Identities = 21/81 (25%), Positives = 35/81 (43%)
Query: 1905 VSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGL 1964
V+PP R R + +I ISW+ G+++ P +G Q ++ I GL
Sbjct: 30 VAPPTRLRYNVISHDSIQISWKAPRGKFGGYKLLVTPTSGGKTNQLNLQNTATKAIIQGL 89
Query: 1965 QPGTDYKIYLYTLNDNARSSP 1985
P +Y + + N + S P
Sbjct: 90 MPDQNYTVQIIAYNKDKESKP 110
Score = 38.9 bits (89), Expect = 0.064
Identities = 21/90 (23%), Positives = 43/90 (47%), Gaps = 2/90 (2%)
Query: 1355 QTAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAV 1414
Q V PPT LR+ I D+++++W P + + +P + +L++ +
Sbjct: 27 QGQVAPPTRLRYNVISHDSIQISWKAPRG-KFGGYKLLVTPTSGGK-TNQLNLQNTATKA 84
Query: 1415 VLTNLLPGTEYVVSVSSVYEQHESTPLRGR 1444
++ L+P Y V + + + ES P +G+
Sbjct: 85 IIQGLMPDQNYTVQIIAYNKDKESKPAQGQ 114
Score = 32.3 bits (72), Expect = 5.9
Identities = 31/123 (25%), Positives = 52/123 (42%), Gaps = 11/123 (8%)
Query: 731 ITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNV 790
I+ S +SW + G+++ + G Q L+L +TAT I L+P + Y V +
Sbjct: 41 ISHDSIQISWKAPRGKFGGYKLLVTPTSGGKTNQ-LNLQNTATKAIIQGLMPDQNYTVQI 99
Query: 791 YQISEDGEQSLILSTSQTTAPD----APPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYS 846
++D E + Q D P P V VD + SRP +P + +
Sbjct: 100 IAYNKDKESK--PAQGQFRIKDLEKRKDPKPRVKVVDRGN----GSRPSSPEEVKFVCQT 153
Query: 847 PSV 849
P++
Sbjct: 154 PAI 156
>gi|157952215 protein tyrosine phosphatase, receptor type, B isoform a
[Homo sapiens]
Length = 2215
Score = 188 bits (478), Expect = 5e-47
Identities = 290/1361 (21%), Positives = 539/1361 (39%), Gaps = 104/1361 (7%)
Query: 768 LPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSI 827
+ +T N+ DL G Y N IS D E++++L T P A + ++ TS+
Sbjct: 291 IDNTTYGCNLQDLQAGTIY--NFRIISLDEERTVVLQTDPL--PPARFGVSKEKTTSTSL 346
Query: 828 VVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETA--NSVTLSDLQPGVQYNITIYAVEE 885
V W+ +T Y + + + E+ N T +L G +YNI I AV
Sbjct: 347 HVWWTPSSGKVTSYEVQLFDENNQKIQGVQIQESTSWNEYTFFNLTAGSKYNIAITAVSG 406
Query: 886 NQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVN 945
+ S V T G+ TVPSP + + I W+ V YR+ ++
Sbjct: 407 GKRSFSVY----TNGS----TVPSPVKDIGISTKANSLLISWSHGSGNVERYRLMLMDKG 458
Query: 946 LPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQF 1005
+ HG + ++A GL+PG Y V + G ++ +T ++ +NL+
Sbjct: 459 IL-VHGGVVDKHATSYA-FHGLTPGYLYNLTVMTEAAGLQNYRWKLVRTAPMEV-SNLKV 515
Query: 1006 VNETDSTVL-VRWTPPRAQITGYRLTVGLTRRGQPRQYNV-GPSVSKYPLRNLQPASEYT 1063
N+ T L V+W P + Y +T L+ +G ++ V P +++ + L P Y
Sbjct: 516 TNDGSLTSLKVKWQRPPGNVDSYNIT--LSHKGTIKESRVLAPWITETHFKELVPGRLYQ 573
Query: 1064 VSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGV---- 1119
V++ + G + K V T + N ++V++W+P + +
Sbjct: 574 VTVSCVSGELSAQKMA-VGRTFPDKVANLEANNNGRMRSLVVSWSPPAGDWEQYRILLFN 632
Query: 1120 ------RPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTP 1173
+ G E + V D+G L PG +Y + ++ G +++ P
Sbjct: 633 DSVVLLNITVGKEETQYVMDDTG------LVPGRQYEVEV-IVESGNLKNSERCQGRTVP 685
Query: 1174 LSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCT 1233
L+ AN + L++ W+ TP + + + + + + D T
Sbjct: 686 LAVLQLRVKHANETS--LSIMWQ---TP-VAEWEKYIISLADRDLLLIHKSLSKDAKEFT 739
Query: 1234 FDNLSPGLEYNVSVYTVKDD-KESVPISDTIIPEVPQLTDLSFVDI-TDSSIGLRWTPLN 1291
F +L PG +Y +V ++ D K S + +P Q+TDL + SS+ WT
Sbjct: 740 FTDLVPGRKYMATVTSISGDLKNSSSVKGRTVPA--QVTDLHVANQGMTSSLFTNWTQAQ 797
Query: 1292 SSTIIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTT 1351
Y++ ++ E + I + + S Y+ L+ G Y + V+T ++GG S+
Sbjct: 798 GDVEF-YQVLLIH--ENVVIKNESISSETSRYSFHSLKSGSLYSV-VVTTVSGGISSRQV 853
Query: 1352 LTQQTAVPPPTD-LRFTNIGP-DTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISP 1409
+ + VP + N G D + V+W P D+ N+ V S + + V L I+
Sbjct: 854 VVEGRTVPSSVSGVTVNNSGRNDYLSVSWLLAPG-DVDNYEVTLS--HDGKVVQSLVIAK 910
Query: 1410 SDNAVVLTNLLPGTEYVVSV---SSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFT 1466
S ++L PG Y V++ S YE H + +++T D G+ S+ + +
Sbjct: 911 SVRECSFSSLTPGRLYTVTITTRSGKYENHSFS----QERTVPDKVQGVSVSNSARSDYL 966
Query: 1467 -VHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGR 1525
V W+ Y + ++ + + +P S N L PG Y V++ +G+
Sbjct: 967 RVSWVHATGDFDHYEVTIKNKNNFIQTKS--IPKSENECVFVQLVPGRLYSVTVTTKSGQ 1024
Query: 1526 EESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRIT--YGETGGNSPVQ 1583
E+ G T+ + +DL + + L ++W V Y I + + P
Sbjct: 1025 YEANEQ-GNGRTIPEPVKDLTLRNRSTEDLHVTWSGANGDVDQYEIQLLFNDMKVFPP-- 1081
Query: 1584 EFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTD 1643
F + + + + L PG Y I V ++G A + ++ + S TD
Sbjct: 1082 -FHLVNTATEYRFTSLTPGRQYKILVLTISGDVQQSAFIEGFTVPSAVKNIHISPNGATD 1140
Query: 1644 VQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSV 1703
S++V W P V Y V+ + ++T E T L+ +Y + +
Sbjct: 1141 ----SLTVNWTPGGGDVDSYTVSAFRHSQK--VDSQTIPKHVFEHTFHRLEAGEQYQIMI 1194
Query: 1704 YAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDG 1763
+ + S ++Q V +A S+ ++W+ G RY + + E+G
Sbjct: 1195 ASVSGSLKNQINVVGRTVPASVQGVIADNAYSSYSLIVSWQKAAGVAERYDILLLT-ENG 1253
Query: 1764 IHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQ 1823
I + + + L PG +Y + ++ + + S+ T A TDL+ T+
Sbjct: 1254 ILLRNTSEPATTKQHKFEDLTPGKKYKIQILTVSGGLFSKEAQTEGRTVPAAVTDLRITE 1313
Query: 1824 VTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKE-INLAPDSSSVVVSGLMVATKYEVS 1882
+ LS +WT +L+ Y + + + G ++E + P S L+ Y++
Sbjct: 1314 NSTRHLSFRWTASEGELSWYNIFLYNPD--GNLQERAQVDPLVQSFSFQNLLQGRMYKMV 1371
Query: 1883 VYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPA 1942
+ L++ T +VS R + T ++ +W + +++
Sbjct: 1372 IVTHSGELSNESFIFGRTVPASVSHLRGSNRN--TTDSLWFNWSPASGDFDFYELILYNP 1429
Query: 1943 NGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRF 2002
NG T + D+ + GL PG Y +++ T + S+ V ++ TA PS + F
Sbjct: 1430 NG-TKKENWKDKDLTEWRFQGLVPGRKYVLWVVT-HSGDLSNKVTAESRTAPSPPSLMSF 1487
Query: 2003 LATTPNSLLVSWQ--PPRARITGYIIKYEKPGSPPREVVPRPRPGVTEAT----ITGLEP 2056
SL ++W+ P + +++ PR+ + P + + GL P
Sbjct: 1488 ADIANTSLAITWKGPPDWTDYNDFELQW-----LPRDALTVFNPYNNRKSEGRIVYGLRP 1542
Query: 2057 GTEYTIYVIALKNNQ---KSEPLIG--RKKTDELPQLVTLP 2092
G Y V + + S+P+ G R K D++ L P
Sbjct: 1543 GRSYQFNVKTVSGDSWKTYSKPIFGSVRTKPDKIQNLHCRP 1583
Score = 169 bits (429), Expect = 2e-41
Identities = 299/1449 (20%), Positives = 554/1449 (38%), Gaps = 137/1449 (9%)
Query: 668 IKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSES 727
++ L+ G +Y ++IS+ + TV +T P P S
Sbjct: 300 LQDLQAGTIYNFRIISLDE---------------------ERTVVLQTDPLPP-ARFGVS 337
Query: 728 VTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTAT--SVNIPDLLPGRK 785
+ T++S V W +S V+ + V+ E + Q + + + + +L G K
Sbjct: 338 KEKTTSTSLHVWWTPSSGKVTSYEVQL-FDENNQKIQGVQIQESTSWNEYTFFNLTAGSK 396
Query: 786 YIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVY 845
Y + + +S G++S + T+ +T P D + S+++ WS + YR++
Sbjct: 397 YNIAITAVS-GGKRSFSVYTNGSTVPSPVKDIGIS-TKANSLLISWSHGSGNVERYRLML 454
Query: 846 SPS---VEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTP 902
V G + + A S L PG YN+T+ ++ + +
Sbjct: 455 MDKGILVHGGVVDKH----ATSYAFHGLTPGYLYNLTVMTEAAGLQNYRWKLVRT----- 505
Query: 903 RSDTVPSPRDLQFVEVTD----VKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLP-IS 957
+P ++ ++VT+ + + W P V Y + + E P I+
Sbjct: 506 ------APMEVSNLKVTNDGSLTSLKVKWQRPPGNVDSYNITLSHKGTIKESRVLAPWIT 559
Query: 958 RNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDS-TVLVR 1016
F E L PG Y V VS G S A T D NL+ N +++V
Sbjct: 560 ETHFKE---LVPGRLYQVTVSCVS-GELSAQKMAVGRTFPDKVANLEANNNGRMRSLVVS 615
Query: 1017 WTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRN--LQPASEYTVSLVAIKGNQE 1074
W+PP YR+ + VG ++Y + + L P +Y V ++ GN +
Sbjct: 616 WSPPAGDWEQYRILL-FNDSVVLLNITVGKEETQYVMDDTGLVPGRQYEVEVIVESGNLK 674
Query: 1075 SPKATGVFTTLQPGSSIPPYNTEVTETTIVITW-TP-APRIGFKLGVRPSQGGEAPREVT 1132
+ + T P + + ET++ I W TP A + + + + ++
Sbjct: 675 NSERCQGRTV--PLAVLQLRVKHANETSLSIMWQTPVAEWEKYIISLADRDLLLIHKSLS 732
Query: 1133 SDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLT 1192
D+ + L PG +Y+ T+ + + + + + V + T+LH+ T L
Sbjct: 733 KDAKEFTFTDLVPGRKYMATVTSISGDLKNSSSVKGRTVP--AQVTDLHVANQGMTSSLF 790
Query: 1193 VSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKD 1252
+W ++ D+ Y++ N N E + ++ S +F +L G Y+V V TV
Sbjct: 791 TNWTQAQG-DVEFYQVLLIHENVVIKN---ESISSETSRYSFHSLKSGSLYSVVVTTVSG 846
Query: 1253 DKES--VPISDTIIPEVPQLTDLSFVDITDSS----IGLRWTPLNSSTIIGYRITVVAAG 1306
S V + +P + +S V + +S + + W L + Y +T+ G
Sbjct: 847 GISSRQVVVEGRTVP-----SSVSGVTVNNSGRNDYLSVSWL-LAPGDVDNYEVTLSHDG 900
Query: 1307 EGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAVPPPTD-LR 1365
+ + + SV + + L PG Y +++ T G+ + +Q+ VP +
Sbjct: 901 KVVQSL--VIAKSVRECSFSSLTPGRLYTVTITT--RSGKYENHSFSQERTVPDKVQGVS 956
Query: 1366 FTNIG-PDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAEL-SISPSDNAVVLTNLLPGT 1423
+N D +RV+W D ++ V +KN+ + + SI S+N V L+PG
Sbjct: 957 VSNSARSDYLRVSWVHATG-DFDHYEVT---IKNKNNFIQTKSIPKSENECVFVQLVPGR 1012
Query: 1424 EYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRH 1483
Y V+V++ Q+E+ +G +T + + + + V W + Y I+
Sbjct: 1013 LYSVTVTTKSGQYEANE-QGNGRTIPEPVKDLTLRNRSTEDLHVTWSGANGDVDQYEIQL 1071
Query: 1484 HPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPR 1543
P V ++ T+LTPG +Y + ++ ++G + I + TV +
Sbjct: 1072 LFNDMKVFPPFHLV-NTATEYRFTSLTPGRQYKILVLTISGDVQQSAFI-EGFTVPSAVK 1129
Query: 1544 DLEVVAATPT-SLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPG 1602
++ + T SL ++W V Y T + V T+P T L+ G
Sbjct: 1130 NIHISPNGATDSLTVNWTPGGGDVDSY--TVSAFRHSQKVDSQTIPKHVFEHTFHRLEAG 1187
Query: 1603 VDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSIS-----VKWLPSS 1657
Y I + +V+G + I++ RT P+ +Q + DN+ S V W ++
Sbjct: 1188 EQYQIMIASVSG-----SLKNQINVVGRTV---PASVQGV-IADNAYSSYSLIVSWQKAA 1238
Query: 1658 SPVTGYRVTTTPKNGPGPTKTKTAGPDQTEM-TIEGLQPTVEYVVSVYAQNP---SGESQ 1713
Y + +NG T+ P T+ E L P +Y + + + S E+Q
Sbjct: 1239 GVAERYDILLLTENGI--LLRNTSEPATTKQHKFEDLTPGKKYKIQILTVSGGLFSKEAQ 1296
Query: 1714 P---LVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPA 1770
V AVT+ L T+ + W + +G++S Y + +P+ + E
Sbjct: 1297 TEGRTVPAAVTD------LRITENSTRHLSFRWTASEGELSWYNIFLYNPDGNLQERAQV 1350
Query: 1771 PDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLS 1830
D + Q L G Y + +V ++ ++ I ++ + T SL
Sbjct: 1351 -DPLVQSFSFQNLLQGRMYKMVIVTHSGELSNESFIFGRTVPASVSHLRGSNRNTTDSLW 1409
Query: 1831 AQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTL 1890
W+P + Y + + G KE D + GL+ KY + V L
Sbjct: 1410 FNWSPASGDFDFYELILY--NPNGTKKENWKDKDLTEWRFQGLVPGRKYVLWVVTHSGDL 1467
Query: 1891 TSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTE--TITGFQVDAVPANGQTPI 1948
+++ T SPP D T++ I+W+ + F++ +P + T
Sbjct: 1468 SNKVTAESRTA---PSPPSLMSFADIANTSLAITWKGPPDWTDYNDFELQWLPRDALTVF 1524
Query: 1949 QRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNA---RSSPVVIDASTAIDAPSNLRFLAT 2005
+ GL+PG Y+ + T++ ++ S P+ T D NL
Sbjct: 1525 NPYNNRKSEGRIVYGLRPGRSYQFNVKTVSGDSWKTYSKPIFGSVRTKPDKIQNLHCRPQ 1584
Query: 2006 TPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVI 2065
++ SW PP + GY I+ K + E + + I L P Y + +
Sbjct: 1585 NSTAIACSWIPPDSDFDGYSIECRKMDTQEVEFSRKLEKEKSLLNIMMLVPHKRYLVSIK 1644
Query: 2066 ALKNNQKSE 2074
SE
Sbjct: 1645 VQSAGMTSE 1653
Score = 164 bits (416), Expect = 8e-40
Identities = 288/1338 (21%), Positives = 506/1338 (37%), Gaps = 116/1338 (8%)
Query: 662 HLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPL 721
H SY GL PG +Y L + + + R+ T +P+
Sbjct: 469 HATSYAFHGLTPGYLY--NLTVMTEAAGLQNYRWKLVRT------------------APM 508
Query: 722 VATSESVT-EITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL 780
++ VT + + +S V W V + + LS +G + L T + +L
Sbjct: 509 EVSNLKVTNDGSLTSLKVKWQRPPGNVDSYNI--TLSHKGTIKESRVLAPWITETHFKEL 566
Query: 781 LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDD-TSIVVRWSRPQAPIT 839
+PGR Y V V +S GE S T PD + + S+VV WS P
Sbjct: 567 VPGRLYQVTVSCVS--GELSAQKMAVGRTFPDKVANLEANNNGRMRSLVVSWSPPAGDWE 624
Query: 840 GYRI-VYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQET 898
YRI +++ SV + + ET + + L PG QY + + N +++
Sbjct: 625 QYRILLFNDSVVLLNITVGKEETQYVMDDTGLVPGRQYEVEVIVESGNLKNSE------- 677
Query: 899 TGTPRSDTVP-SPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPIS 957
+ TVP + L+ + ++IMW P + Y + + +L H + L
Sbjct: 678 --RCQGRTVPLAVLQLRVKHANETSLSIMWQTPVAEWEKYIISLADRDLLLIH-KSLSKD 734
Query: 958 RNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNE-TDSTVLVR 1016
F T L PG Y V ++S ++ +T T+L N+ S++
Sbjct: 735 AKEFT-FTDLVPGRKYMATVTSISGDLKNSSSVKGRTVPAQV-TDLHVANQGMTSSLFTN 792
Query: 1017 WTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESP 1076
WT + + Y++ + + + ++ S+Y +L+ S Y+V + + G S
Sbjct: 793 WTQAQGDVEFYQVLL-IHENVVIKNESISSETSRYSFHSLKSGSLYSVVVTTVSGGISSR 851
Query: 1077 KATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPRE--VTSD 1134
+ T+ S N + ++W AP V S G+ + +
Sbjct: 852 QVVVEGRTVPSSVSGVTVNNSGRNDYLSVSWLLAPGDVDNYEVTLSHDGKVVQSLVIAKS 911
Query: 1135 SGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVS 1194
S LTPG Y TI E + + V ++ A D L VS
Sbjct: 912 VRECSFSSLTPGRLYTVTITTRSGKYENHSFSQERTVPDKVQGVSVSNSARSD--YLRVS 969
Query: 1195 WERSTTPDITGYRITTTPTNGQQGNSLE-EVVHADQSSCTFDNLSPGLEYNVSVYTVKDD 1253
W + T D Y +T N N ++ + + ++ C F L PG Y+V+V T
Sbjct: 970 WVHA-TGDFDHYEVTIKNKN----NFIQTKSIPKSENECVFVQLVPGRLYSVTVTTKSGQ 1024
Query: 1254 KESVPISD-TIIPEVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIF 1312
E+ + IPE + DL+ + + + + W+ N + Y I ++ + +F
Sbjct: 1025 YEANEQGNGRTIPE--PVKDLTLRNRSTEDLHVTWSGANGD-VDQYEIQLLF--NDMKVF 1079
Query: 1313 EDF-VDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAVPPPTDLRFTNIGP 1371
F + ++ Y T L PG Y I V+T+ G+ + + V P+ ++ +I P
Sbjct: 1080 PPFHLVNTATEYRFTSLTPGRQYKILVLTI--SGDVQQSAFIEGFTV--PSAVKNIHISP 1135
Query: 1372 ----DTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVV 1427
D++ V W P D+ ++ V S ++ + V +I L G +Y +
Sbjct: 1136 NGATDSLTVNWTPGGG-DVDSYTV--SAFRHSQKVDSQTIPKHVFEHTFHRLEAGEQYQI 1192
Query: 1428 SVSSVYEQHESTPLRGR-QKTGLDSPTGID--FSDITANSFT--VHWIAPRATITGYRIR 1482
++SV S L+ + G P + +D +S++ V W Y I
Sbjct: 1193 MIASV-----SGSLKNQINVVGRTVPASVQGVIADNAYSSYSLIVSWQKAAGVAERYDIL 1247
Query: 1483 HHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVP 1542
E+ R P + +LTPG +Y + I+ ++G S + TV
Sbjct: 1248 LLTEN-GILLRNTSEPATTKQHKFEDLTPGKKYKIQILTVSGGLFSKEAQTEGRTVPAAV 1306
Query: 1543 RDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPG 1602
DL + + L W A + +Y I GN + P +S + L G
Sbjct: 1307 TDLRITENSTRHLSFRWTASEGELSWYNIFLYNPDGNLQERAQVDPLVQS-FSFQNLLQG 1365
Query: 1603 VDYTITVYAVTGRGDSPA----SSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSS 1658
Y + + +G + + + P S+++ + S TD S+ W P+S
Sbjct: 1366 RMYKMVIVTHSGELSNESFIFGRTVPASVSHL----RGSNRNTTD----SLWFNWSPASG 1417
Query: 1659 PVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE-SQPLVQ 1717
Y + N G K D TE +GL P +YV+ V SG+ S +
Sbjct: 1418 DFDFYELILYNPN--GTKKENWKDKDLTEWRFQGLVPGRKYVLWVVTH--SGDLSNKVTA 1473
Query: 1718 TAVTNIDRPKGLAFTDVDVDSIKIAWESPQG--QVSRYRVTYSSPEDGIHELFPAPDGEE 1775
+ T P ++F D+ S+ I W+ P + + + + P D + P + +
Sbjct: 1474 ESRTAPSPPSLMSFADIANTSLAITWKGPPDWTDYNDFELQW-LPRDALTVFNPYNNRKS 1532
Query: 1776 DTAELQGLRPGSEYTVSVVALHDD---MESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQ 1832
+ + GLRPG Y +V + D S+P+ G+ T +L T+++
Sbjct: 1533 EGRIVYGLRPGRSYQFNVKTVSGDSWKTYSKPIFGSVRTKPDKIQNLHCRPQNSTAIACS 1592
Query: 1833 WTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTS 1892
W PP+ GY + + L + S + + L+ +Y VS+ +TS
Sbjct: 1593 WIPPDSDFDGYSIECRKMDTQEVEFSRKLEKEKSLLNIMMLVPHKRYLVSIKVQSAGMTS 1652
Query: 1893 RPAQGVVTTL--ENVSPPRRARVTD--------ATETTITISWRTKTE-TITGFQVDAVP 1941
+ T+ PP RV + + T+ SW + T + F V
Sbjct: 1653 EVVEDSTITMIDRPPPPPPHIRVNEKDVLISKSSINFTVNCSWFSDTNGAVKYFTVVVRE 1712
Query: 1942 ANGQTPIQRTIKPDVRSY 1959
A+G ++ + + SY
Sbjct: 1713 ADGSDELKPEQQHPLPSY 1730
Score = 137 bits (346), Expect = 1e-31
Identities = 272/1338 (20%), Positives = 499/1338 (37%), Gaps = 115/1338 (8%)
Query: 798 EQSLILSTSQ----TTAPDAPPDP-------TVDQVDDTSIVVRWSRPQAPITGYRIVYS 846
+ S +LST+Q TT +P + S+ ++W +P + ++YS
Sbjct: 219 DTSWVLSTTQPFSSTTEETGLAEPERCNFTLAESKASSHSVSIQWRILGSPCN-FSLIYS 277
Query: 847 PSVEGSST--ELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRS 904
G++ + T L DLQ G YN I +++E + VV+Q +
Sbjct: 278 SDTLGAALCPTFRIDNTTYGCNLQDLQAGTIYNFRIISLDEERT---VVLQ--------T 326
Query: 905 DTVPSPR-DLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAE 963
D +P R + + T + + WTP VT Y V + N G ++ S ++ E
Sbjct: 327 DPLPPARFGVSKEKTTSTSLHVWWTPSSGKVTSYEVQLFDENNQKIQGVQIQES-TSWNE 385
Query: 964 VT--GLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPR 1021
T L+ G Y + AVS G+ S + +T + +P ++ +++L+ W+
Sbjct: 386 YTFFNLTAGSKYNIAITAVSGGKRSFSVYTNGST-VPSPVKDIGISTKANSLLISWSHGS 444
Query: 1022 AQITGYRLTV---GLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKA 1078
+ YRL + G+ G V + Y L P Y ++++ ++ +
Sbjct: 445 GNVERYRLMLMDKGILVHGGV----VDKHATSYAFHGLTPGYLYNLTVMTEAAGLQNYRW 500
Query: 1079 TGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGG--EAPREVTSDSG 1136
V T S++ N + + T++ + W P + S G + R +
Sbjct: 501 KLVRTAPMEVSNLKVTN-DGSLTSLKVKWQRPPGNVDSYNITLSHKGTIKESRVLAPWIT 559
Query: 1137 SIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGV--LTVS 1194
L PG Y T+ + V + P +LEAN + + L VS
Sbjct: 560 ETHFKELVPGRLYQVTVSCVSGELSAQKMAVGRTF----PDKVANLEANNNGRMRSLVVS 615
Query: 1195 WERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDN--LSPGLEYNVSVYTVKD 1252
W D YRI L V +++ D+ L PG +Y V V
Sbjct: 616 WS-PPAGDWEQYRILLF---NDSVVLLNITVGKEETQYVMDDTGLVPGRQYEVEVIVESG 671
Query: 1253 D-KESVPISDTIIPEVPQLTDLSFVDITDSSIGLRW-TPLNSSTIIGYRITVVAAGEGIP 1310
+ K S +P + L ++S+ + W TP+ + + A +
Sbjct: 672 NLKNSERCQGRTVPLA--VLQLRVKHANETSLSIMWQTPVAEWE----KYIISLADRDLL 725
Query: 1311 IFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAVPPPTDLRFTNIG 1370
+ + +T T L PG Y ++ +T I+G +++ +T TDL N G
Sbjct: 726 LIHKSLSKDAKEFTFTDLVPGRKY-MATVTSISGDLKNSSSVKGRTVPAQVTDLHVANQG 784
Query: 1371 PDTMRVT-WAPPPS-IDLTNFLVRYSPV--KNEEDVAELSISPSDNAVVLTNLLPGTEYV 1426
+ T W ++ L+ + V KNE SIS + +L G+ Y
Sbjct: 785 MTSSLFTNWTQAQGDVEFYQVLLIHENVVIKNE------SISSETSRYSFHSLKSGSLYS 838
Query: 1427 VSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSF-TVHWIAPRATITGYRIRHHP 1485
V V++V S + +T S +G+ ++ N + +V W+ + Y +
Sbjct: 839 VVVTTVSGGISSRQVVVEGRTVPSSVSGVTVNNSGRNDYLSVSWLLAPGDVDNYEVTL-- 896
Query: 1486 EHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDL 1545
H + + S + ++LTPG Y V+I +G+ E+ Q+ TV D + +
Sbjct: 897 SHDGKVVQSLVIAKSVRECSFSSLTPGRLYTVTITTRSGKYENHSF-SQERTVPDKVQGV 955
Query: 1546 EVV-AATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVD 1604
V +A L +SW +Y +T N+ +Q ++P S++ L PG
Sbjct: 956 SVSNSARSDYLRVSWVHATGDFDHYEVTIKNK--NNFIQTKSIPKSENECVFVQLVPGRL 1013
Query: 1605 YTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYR 1664
Y++TV +G+ ++ N RT + + + + + V W ++ V Y
Sbjct: 1014 YSVTVTTKSGQYEANEQG-----NGRTIPEPVKDLTLRNRSTEDLHVTWSGANGDVDQYE 1068
Query: 1665 VT---TTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQ---- 1717
+ K P TA TE L P +Y + V + + ++
Sbjct: 1069 IQLLFNDMKVFPPFHLVNTA----TEYRFTSLTPGRQYKILVLTISGDVQQSAFIEGFTV 1124
Query: 1718 -TAVTNID-RPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEE 1775
+AV NI P G DS+ + W G V Y V+ + E
Sbjct: 1125 PSAVKNIHISPNGAT------DSLTVNWTPGGGDVDSYTVSAFRHSQKVDSQTIPKHVFE 1178
Query: 1776 DTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTD--LKFTQVTPTSLSAQW 1833
T L G +Y + + ++ +++Q I +PA + + SL W
Sbjct: 1179 HT--FHRLEAGEQYQIMIASVSGSLKNQ--INVVGRTVPASVQGVIADNAYSSYSLIVSW 1234
Query: 1834 TPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSR 1893
Y + + E ++ + + L KY++ + + L S+
Sbjct: 1235 QKAAGVAERYDILLLT-ENGILLRNTSEPATTKQHKFEDLTPGKKYKIQILTVSGGLFSK 1293
Query: 1894 PAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIK 1953
AQ T+ + R+T+ + ++ W ++ + + +G + +
Sbjct: 1294 EAQTEGRTVP--AAVTDLRITENSTRHLSFRWTASEGELSWYNIFLYNPDGNLQERAQVD 1351
Query: 1954 PDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFL-ATTPNSLLV 2012
P V+S++ L G YK+ + T + S+ I T + S+LR T +SL
Sbjct: 1352 PLVQSFSFQNLLQGRMYKMVIVT-HSGELSNESFIFGRTVPASVSHLRGSNRNTTDSLWF 1410
Query: 2013 SWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQK 2072
+W P Y + P +E +TE GL PG +Y ++V+ +
Sbjct: 1411 NWSPASGDFDFYELILYNPNGTKKE--NWKDKDLTEWRFQGLVPGRKYVLWVVTHSGDLS 1468
Query: 2073 SEPLIGRKKTDELPQLVT 2090
++ + P L++
Sbjct: 1469 NKVTAESRTAPSPPSLMS 1486
Score = 35.4 bits (80), Expect = 0.70
Identities = 37/194 (19%), Positives = 76/194 (39%), Gaps = 25/194 (12%)
Query: 628 IQWNAPQP-SHISKYILRWRPKNSV---GRWKEATIPGHLNSYTIKGLKPGVVYEGQLIS 683
I W P + + + L+W P++++ + G + + GL+PG Y+ + +
Sbjct: 1497 ITWKGPPDWTDYNDFELQWLPRDALTVFNPYNNRKSEGRI----VYGLRPGRSYQFNVKT 1552
Query: 684 IQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSA 743
+ + ++ F + T N L ++ T I S W+
Sbjct: 1553 VSGDSWKTYSKPIFGSVRTKPDKIQN-----------LHCRPQNSTAIACS-----WIPP 1596
Query: 744 SDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLIL 803
G+ +E + + L + +NI L+P ++Y+V++ ++ G S ++
Sbjct: 1597 DSDFDGYSIECRKMDTQEVEFSRKLEKEKSLLNIMMLVPHKRYLVSI-KVQSAGMTSEVV 1655
Query: 804 STSQTTAPDAPPDP 817
S T D PP P
Sbjct: 1656 EDSTITMIDRPPPP 1669
>gi|157952213 protein tyrosine phosphatase, receptor type, B isoform b
precursor [Homo sapiens]
Length = 1997
Score = 188 bits (478), Expect = 5e-47
Identities = 290/1361 (21%), Positives = 539/1361 (39%), Gaps = 104/1361 (7%)
Query: 768 LPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSI 827
+ +T N+ DL G Y N IS D E++++L T P A + ++ TS+
Sbjct: 73 IDNTTYGCNLQDLQAGTIY--NFRIISLDEERTVVLQTDPL--PPARFGVSKEKTTSTSL 128
Query: 828 VVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETA--NSVTLSDLQPGVQYNITIYAVEE 885
V W+ +T Y + + + E+ N T +L G +YNI I AV
Sbjct: 129 HVWWTPSSGKVTSYEVQLFDENNQKIQGVQIQESTSWNEYTFFNLTAGSKYNIAITAVSG 188
Query: 886 NQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVN 945
+ S V T G+ TVPSP + + I W+ V YR+ ++
Sbjct: 189 GKRSFSVY----TNGS----TVPSPVKDIGISTKANSLLISWSHGSGNVERYRLMLMDKG 240
Query: 946 LPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQF 1005
+ HG + ++A GL+PG Y V + G ++ +T ++ +NL+
Sbjct: 241 IL-VHGGVVDKHATSYA-FHGLTPGYLYNLTVMTEAAGLQNYRWKLVRTAPMEV-SNLKV 297
Query: 1006 VNETDSTVL-VRWTPPRAQITGYRLTVGLTRRGQPRQYNV-GPSVSKYPLRNLQPASEYT 1063
N+ T L V+W P + Y +T L+ +G ++ V P +++ + L P Y
Sbjct: 298 TNDGSLTSLKVKWQRPPGNVDSYNIT--LSHKGTIKESRVLAPWITETHFKELVPGRLYQ 355
Query: 1064 VSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGV---- 1119
V++ + G + K V T + N ++V++W+P + +
Sbjct: 356 VTVSCVSGELSAQKMA-VGRTFPDKVANLEANNNGRMRSLVVSWSPPAGDWEQYRILLFN 414
Query: 1120 ------RPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTP 1173
+ G E + V D+G L PG +Y + ++ G +++ P
Sbjct: 415 DSVVLLNITVGKEETQYVMDDTG------LVPGRQYEVEV-IVESGNLKNSERCQGRTVP 467
Query: 1174 LSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCT 1233
L+ AN + L++ W+ TP + + + + + + D T
Sbjct: 468 LAVLQLRVKHANETS--LSIMWQ---TP-VAEWEKYIISLADRDLLLIHKSLSKDAKEFT 521
Query: 1234 FDNLSPGLEYNVSVYTVKDD-KESVPISDTIIPEVPQLTDLSFVDI-TDSSIGLRWTPLN 1291
F +L PG +Y +V ++ D K S + +P Q+TDL + SS+ WT
Sbjct: 522 FTDLVPGRKYMATVTSISGDLKNSSSVKGRTVPA--QVTDLHVANQGMTSSLFTNWTQAQ 579
Query: 1292 SSTIIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTT 1351
Y++ ++ E + I + + S Y+ L+ G Y + V+T ++GG S+
Sbjct: 580 GDVEF-YQVLLIH--ENVVIKNESISSETSRYSFHSLKSGSLYSV-VVTTVSGGISSRQV 635
Query: 1352 LTQQTAVPPPTD-LRFTNIGP-DTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISP 1409
+ + VP + N G D + V+W P D+ N+ V S + + V L I+
Sbjct: 636 VVEGRTVPSSVSGVTVNNSGRNDYLSVSWLLAPG-DVDNYEVTLS--HDGKVVQSLVIAK 692
Query: 1410 SDNAVVLTNLLPGTEYVVSV---SSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFT 1466
S ++L PG Y V++ S YE H + +++T D G+ S+ + +
Sbjct: 693 SVRECSFSSLTPGRLYTVTITTRSGKYENHSFS----QERTVPDKVQGVSVSNSARSDYL 748
Query: 1467 -VHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGR 1525
V W+ Y + ++ + + +P S N L PG Y V++ +G+
Sbjct: 749 RVSWVHATGDFDHYEVTIKNKNNFIQTKS--IPKSENECVFVQLVPGRLYSVTVTTKSGQ 806
Query: 1526 EESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRIT--YGETGGNSPVQ 1583
E+ G T+ + +DL + + L ++W V Y I + + P
Sbjct: 807 YEANEQ-GNGRTIPEPVKDLTLRNRSTEDLHVTWSGANGDVDQYEIQLLFNDMKVFPP-- 863
Query: 1584 EFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTD 1643
F + + + + L PG Y I V ++G A + ++ + S TD
Sbjct: 864 -FHLVNTATEYRFTSLTPGRQYKILVLTISGDVQQSAFIEGFTVPSAVKNIHISPNGATD 922
Query: 1644 VQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSV 1703
S++V W P V Y V+ + ++T E T L+ +Y + +
Sbjct: 923 ----SLTVNWTPGGGDVDSYTVSAFRHSQK--VDSQTIPKHVFEHTFHRLEAGEQYQIMI 976
Query: 1704 YAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDG 1763
+ + S ++Q V +A S+ ++W+ G RY + + E+G
Sbjct: 977 ASVSGSLKNQINVVGRTVPASVQGVIADNAYSSYSLIVSWQKAAGVAERYDILLLT-ENG 1035
Query: 1764 IHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQ 1823
I + + + L PG +Y + ++ + + S+ T A TDL+ T+
Sbjct: 1036 ILLRNTSEPATTKQHKFEDLTPGKKYKIQILTVSGGLFSKEAQTEGRTVPAAVTDLRITE 1095
Query: 1824 VTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKE-INLAPDSSSVVVSGLMVATKYEVS 1882
+ LS +WT +L+ Y + + + G ++E + P S L+ Y++
Sbjct: 1096 NSTRHLSFRWTASEGELSWYNIFLYNPD--GNLQERAQVDPLVQSFSFQNLLQGRMYKMV 1153
Query: 1883 VYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPA 1942
+ L++ T +VS R + T ++ +W + +++
Sbjct: 1154 IVTHSGELSNESFIFGRTVPASVSHLRGSNRN--TTDSLWFNWSPASGDFDFYELILYNP 1211
Query: 1943 NGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRF 2002
NG T + D+ + GL PG Y +++ T + S+ V ++ TA PS + F
Sbjct: 1212 NG-TKKENWKDKDLTEWRFQGLVPGRKYVLWVVT-HSGDLSNKVTAESRTAPSPPSLMSF 1269
Query: 2003 LATTPNSLLVSWQ--PPRARITGYIIKYEKPGSPPREVVPRPRPGVTEAT----ITGLEP 2056
SL ++W+ P + +++ PR+ + P + + GL P
Sbjct: 1270 ADIANTSLAITWKGPPDWTDYNDFELQW-----LPRDALTVFNPYNNRKSEGRIVYGLRP 1324
Query: 2057 GTEYTIYVIALKNNQ---KSEPLIG--RKKTDELPQLVTLP 2092
G Y V + + S+P+ G R K D++ L P
Sbjct: 1325 GRSYQFNVKTVSGDSWKTYSKPIFGSVRTKPDKIQNLHCRP 1365
Score = 169 bits (429), Expect = 2e-41
Identities = 299/1449 (20%), Positives = 554/1449 (38%), Gaps = 137/1449 (9%)
Query: 668 IKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSES 727
++ L+ G +Y ++IS+ + TV +T P P S
Sbjct: 82 LQDLQAGTIYNFRIISLDE---------------------ERTVVLQTDPLPP-ARFGVS 119
Query: 728 VTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTAT--SVNIPDLLPGRK 785
+ T++S V W +S V+ + V+ E + Q + + + + +L G K
Sbjct: 120 KEKTTSTSLHVWWTPSSGKVTSYEVQL-FDENNQKIQGVQIQESTSWNEYTFFNLTAGSK 178
Query: 786 YIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVY 845
Y + + +S G++S + T+ +T P D + S+++ WS + YR++
Sbjct: 179 YNIAITAVS-GGKRSFSVYTNGSTVPSPVKDIGIS-TKANSLLISWSHGSGNVERYRLML 236
Query: 846 SPS---VEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTP 902
V G + + A S L PG YN+T+ ++ + +
Sbjct: 237 MDKGILVHGGVVDKH----ATSYAFHGLTPGYLYNLTVMTEAAGLQNYRWKLVRT----- 287
Query: 903 RSDTVPSPRDLQFVEVTD----VKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLP-IS 957
+P ++ ++VT+ + + W P V Y + + E P I+
Sbjct: 288 ------APMEVSNLKVTNDGSLTSLKVKWQRPPGNVDSYNITLSHKGTIKESRVLAPWIT 341
Query: 958 RNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDS-TVLVR 1016
F E L PG Y V VS G S A T D NL+ N +++V
Sbjct: 342 ETHFKE---LVPGRLYQVTVSCVS-GELSAQKMAVGRTFPDKVANLEANNNGRMRSLVVS 397
Query: 1017 WTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRN--LQPASEYTVSLVAIKGNQE 1074
W+PP YR+ + VG ++Y + + L P +Y V ++ GN +
Sbjct: 398 WSPPAGDWEQYRILL-FNDSVVLLNITVGKEETQYVMDDTGLVPGRQYEVEVIVESGNLK 456
Query: 1075 SPKATGVFTTLQPGSSIPPYNTEVTETTIVITW-TP-APRIGFKLGVRPSQGGEAPREVT 1132
+ + T P + + ET++ I W TP A + + + + ++
Sbjct: 457 NSERCQGRTV--PLAVLQLRVKHANETSLSIMWQTPVAEWEKYIISLADRDLLLIHKSLS 514
Query: 1133 SDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLT 1192
D+ + L PG +Y+ T+ + + + + + V + T+LH+ T L
Sbjct: 515 KDAKEFTFTDLVPGRKYMATVTSISGDLKNSSSVKGRTVP--AQVTDLHVANQGMTSSLF 572
Query: 1193 VSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKD 1252
+W ++ D+ Y++ N N E + ++ S +F +L G Y+V V TV
Sbjct: 573 TNWTQAQG-DVEFYQVLLIHENVVIKN---ESISSETSRYSFHSLKSGSLYSVVVTTVSG 628
Query: 1253 DKES--VPISDTIIPEVPQLTDLSFVDITDSS----IGLRWTPLNSSTIIGYRITVVAAG 1306
S V + +P + +S V + +S + + W L + Y +T+ G
Sbjct: 629 GISSRQVVVEGRTVP-----SSVSGVTVNNSGRNDYLSVSWL-LAPGDVDNYEVTLSHDG 682
Query: 1307 EGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAVPPPTD-LR 1365
+ + + SV + + L PG Y +++ T G+ + +Q+ VP +
Sbjct: 683 KVVQSL--VIAKSVRECSFSSLTPGRLYTVTITT--RSGKYENHSFSQERTVPDKVQGVS 738
Query: 1366 FTNIG-PDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAEL-SISPSDNAVVLTNLLPGT 1423
+N D +RV+W D ++ V +KN+ + + SI S+N V L+PG
Sbjct: 739 VSNSARSDYLRVSWVHATG-DFDHYEVT---IKNKNNFIQTKSIPKSENECVFVQLVPGR 794
Query: 1424 EYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRH 1483
Y V+V++ Q+E+ +G +T + + + + V W + Y I+
Sbjct: 795 LYSVTVTTKSGQYEANE-QGNGRTIPEPVKDLTLRNRSTEDLHVTWSGANGDVDQYEIQL 853
Query: 1484 HPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPR 1543
P V ++ T+LTPG +Y + ++ ++G + I + TV +
Sbjct: 854 LFNDMKVFPPFHLV-NTATEYRFTSLTPGRQYKILVLTISGDVQQSAFI-EGFTVPSAVK 911
Query: 1544 DLEVVAATPT-SLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPG 1602
++ + T SL ++W V Y T + V T+P T L+ G
Sbjct: 912 NIHISPNGATDSLTVNWTPGGGDVDSY--TVSAFRHSQKVDSQTIPKHVFEHTFHRLEAG 969
Query: 1603 VDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSIS-----VKWLPSS 1657
Y I + +V+G + I++ RT P+ +Q + DN+ S V W ++
Sbjct: 970 EQYQIMIASVSG-----SLKNQINVVGRTV---PASVQGV-IADNAYSSYSLIVSWQKAA 1020
Query: 1658 SPVTGYRVTTTPKNGPGPTKTKTAGPDQTEM-TIEGLQPTVEYVVSVYAQNP---SGESQ 1713
Y + +NG T+ P T+ E L P +Y + + + S E+Q
Sbjct: 1021 GVAERYDILLLTENGI--LLRNTSEPATTKQHKFEDLTPGKKYKIQILTVSGGLFSKEAQ 1078
Query: 1714 P---LVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPA 1770
V AVT+ L T+ + W + +G++S Y + +P+ + E
Sbjct: 1079 TEGRTVPAAVTD------LRITENSTRHLSFRWTASEGELSWYNIFLYNPDGNLQERAQV 1132
Query: 1771 PDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLS 1830
D + Q L G Y + +V ++ ++ I ++ + T SL
Sbjct: 1133 -DPLVQSFSFQNLLQGRMYKMVIVTHSGELSNESFIFGRTVPASVSHLRGSNRNTTDSLW 1191
Query: 1831 AQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTL 1890
W+P + Y + + G KE D + GL+ KY + V L
Sbjct: 1192 FNWSPASGDFDFYELILY--NPNGTKKENWKDKDLTEWRFQGLVPGRKYVLWVVTHSGDL 1249
Query: 1891 TSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTE--TITGFQVDAVPANGQTPI 1948
+++ T SPP D T++ I+W+ + F++ +P + T
Sbjct: 1250 SNKVTAESRTA---PSPPSLMSFADIANTSLAITWKGPPDWTDYNDFELQWLPRDALTVF 1306
Query: 1949 QRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNA---RSSPVVIDASTAIDAPSNLRFLAT 2005
+ GL+PG Y+ + T++ ++ S P+ T D NL
Sbjct: 1307 NPYNNRKSEGRIVYGLRPGRSYQFNVKTVSGDSWKTYSKPIFGSVRTKPDKIQNLHCRPQ 1366
Query: 2006 TPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVI 2065
++ SW PP + GY I+ K + E + + I L P Y + +
Sbjct: 1367 NSTAIACSWIPPDSDFDGYSIECRKMDTQEVEFSRKLEKEKSLLNIMMLVPHKRYLVSIK 1426
Query: 2066 ALKNNQKSE 2074
SE
Sbjct: 1427 VQSAGMTSE 1435
Score = 164 bits (416), Expect = 8e-40
Identities = 288/1338 (21%), Positives = 506/1338 (37%), Gaps = 116/1338 (8%)
Query: 662 HLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPL 721
H SY GL PG +Y L + + + R+ T +P+
Sbjct: 251 HATSYAFHGLTPGYLY--NLTVMTEAAGLQNYRWKLVRT------------------APM 290
Query: 722 VATSESVT-EITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL 780
++ VT + + +S V W V + + LS +G + L T + +L
Sbjct: 291 EVSNLKVTNDGSLTSLKVKWQRPPGNVDSYNI--TLSHKGTIKESRVLAPWITETHFKEL 348
Query: 781 LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDD-TSIVVRWSRPQAPIT 839
+PGR Y V V +S GE S T PD + + S+VV WS P
Sbjct: 349 VPGRLYQVTVSCVS--GELSAQKMAVGRTFPDKVANLEANNNGRMRSLVVSWSPPAGDWE 406
Query: 840 GYRI-VYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQET 898
YRI +++ SV + + ET + + L PG QY + + N +++
Sbjct: 407 QYRILLFNDSVVLLNITVGKEETQYVMDDTGLVPGRQYEVEVIVESGNLKNSE------- 459
Query: 899 TGTPRSDTVP-SPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPIS 957
+ TVP + L+ + ++IMW P + Y + + +L H + L
Sbjct: 460 --RCQGRTVPLAVLQLRVKHANETSLSIMWQTPVAEWEKYIISLADRDLLLIH-KSLSKD 516
Query: 958 RNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNE-TDSTVLVR 1016
F T L PG Y V ++S ++ +T T+L N+ S++
Sbjct: 517 AKEFT-FTDLVPGRKYMATVTSISGDLKNSSSVKGRTVPAQV-TDLHVANQGMTSSLFTN 574
Query: 1017 WTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESP 1076
WT + + Y++ + + + ++ S+Y +L+ S Y+V + + G S
Sbjct: 575 WTQAQGDVEFYQVLL-IHENVVIKNESISSETSRYSFHSLKSGSLYSVVVTTVSGGISSR 633
Query: 1077 KATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPRE--VTSD 1134
+ T+ S N + ++W AP V S G+ + +
Sbjct: 634 QVVVEGRTVPSSVSGVTVNNSGRNDYLSVSWLLAPGDVDNYEVTLSHDGKVVQSLVIAKS 693
Query: 1135 SGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVS 1194
S LTPG Y TI E + + V ++ A D L VS
Sbjct: 694 VRECSFSSLTPGRLYTVTITTRSGKYENHSFSQERTVPDKVQGVSVSNSARSD--YLRVS 751
Query: 1195 WERSTTPDITGYRITTTPTNGQQGNSLE-EVVHADQSSCTFDNLSPGLEYNVSVYTVKDD 1253
W + T D Y +T N N ++ + + ++ C F L PG Y+V+V T
Sbjct: 752 WVHA-TGDFDHYEVTIKNKN----NFIQTKSIPKSENECVFVQLVPGRLYSVTVTTKSGQ 806
Query: 1254 KESVPISD-TIIPEVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIF 1312
E+ + IPE + DL+ + + + + W+ N + Y I ++ + +F
Sbjct: 807 YEANEQGNGRTIPE--PVKDLTLRNRSTEDLHVTWSGANGD-VDQYEIQLLF--NDMKVF 861
Query: 1313 EDF-VDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAVPPPTDLRFTNIGP 1371
F + ++ Y T L PG Y I V+T+ G+ + + V P+ ++ +I P
Sbjct: 862 PPFHLVNTATEYRFTSLTPGRQYKILVLTI--SGDVQQSAFIEGFTV--PSAVKNIHISP 917
Query: 1372 ----DTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVV 1427
D++ V W P D+ ++ V S ++ + V +I L G +Y +
Sbjct: 918 NGATDSLTVNWTPGGG-DVDSYTV--SAFRHSQKVDSQTIPKHVFEHTFHRLEAGEQYQI 974
Query: 1428 SVSSVYEQHESTPLRGR-QKTGLDSPTGID--FSDITANSFT--VHWIAPRATITGYRIR 1482
++SV S L+ + G P + +D +S++ V W Y I
Sbjct: 975 MIASV-----SGSLKNQINVVGRTVPASVQGVIADNAYSSYSLIVSWQKAAGVAERYDIL 1029
Query: 1483 HHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVP 1542
E+ R P + +LTPG +Y + I+ ++G S + TV
Sbjct: 1030 LLTEN-GILLRNTSEPATTKQHKFEDLTPGKKYKIQILTVSGGLFSKEAQTEGRTVPAAV 1088
Query: 1543 RDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPG 1602
DL + + L W A + +Y I GN + P +S + L G
Sbjct: 1089 TDLRITENSTRHLSFRWTASEGELSWYNIFLYNPDGNLQERAQVDPLVQS-FSFQNLLQG 1147
Query: 1603 VDYTITVYAVTGRGDSPA----SSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSS 1658
Y + + +G + + + P S+++ + S TD S+ W P+S
Sbjct: 1148 RMYKMVIVTHSGELSNESFIFGRTVPASVSHL----RGSNRNTTD----SLWFNWSPASG 1199
Query: 1659 PVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE-SQPLVQ 1717
Y + N G K D TE +GL P +YV+ V SG+ S +
Sbjct: 1200 DFDFYELILYNPN--GTKKENWKDKDLTEWRFQGLVPGRKYVLWVVTH--SGDLSNKVTA 1255
Query: 1718 TAVTNIDRPKGLAFTDVDVDSIKIAWESPQG--QVSRYRVTYSSPEDGIHELFPAPDGEE 1775
+ T P ++F D+ S+ I W+ P + + + + P D + P + +
Sbjct: 1256 ESRTAPSPPSLMSFADIANTSLAITWKGPPDWTDYNDFELQW-LPRDALTVFNPYNNRKS 1314
Query: 1776 DTAELQGLRPGSEYTVSVVALHDD---MESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQ 1832
+ + GLRPG Y +V + D S+P+ G+ T +L T+++
Sbjct: 1315 EGRIVYGLRPGRSYQFNVKTVSGDSWKTYSKPIFGSVRTKPDKIQNLHCRPQNSTAIACS 1374
Query: 1833 WTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTS 1892
W PP+ GY + + L + S + + L+ +Y VS+ +TS
Sbjct: 1375 WIPPDSDFDGYSIECRKMDTQEVEFSRKLEKEKSLLNIMMLVPHKRYLVSIKVQSAGMTS 1434
Query: 1893 RPAQGVVTTL--ENVSPPRRARVTD--------ATETTITISWRTKTE-TITGFQVDAVP 1941
+ T+ PP RV + + T+ SW + T + F V
Sbjct: 1435 EVVEDSTITMIDRPPPPPPHIRVNEKDVLISKSSINFTVNCSWFSDTNGAVKYFTVVVRE 1494
Query: 1942 ANGQTPIQRTIKPDVRSY 1959
A+G ++ + + SY
Sbjct: 1495 ADGSDELKPEQQHPLPSY 1512
Score = 137 bits (345), Expect = 1e-31
Identities = 264/1299 (20%), Positives = 486/1299 (37%), Gaps = 104/1299 (8%)
Query: 826 SIVVRWSRPQAPITGYRIVYSPSVEGSST--ELNLPETANSVTLSDLQPGVQYNITIYAV 883
S+ ++W +P + ++YS G++ + T L DLQ G YN I ++
Sbjct: 40 SVSIQWRILGSPCN-FSLIYSSDTLGAALCPTFRIDNTTYGCNLQDLQAGTIYNFRIISL 98
Query: 884 EENQESTPVVIQQETTGTPRSDTVPSPR-DLQFVEVTDVKVTIMWTPPESAVTGYRVDVI 942
+E + VV+Q +D +P R + + T + + WTP VT Y V +
Sbjct: 99 DEERT---VVLQ--------TDPLPPARFGVSKEKTTSTSLHVWWTPSSGKVTSYEVQLF 147
Query: 943 PVNLPGEHGQRLPISRNTFAEVT--GLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAP 1000
N G ++ S ++ E T L+ G Y + AVS G+ S + +T + +P
Sbjct: 148 DENNQKIQGVQIQES-TSWNEYTFFNLTAGSKYNIAITAVSGGKRSFSVYTNGST-VPSP 205
Query: 1001 TNLQFVNETDSTVLVRWTPPRAQITGYRLTV---GLTRRGQPRQYNVGPSVSKYPLRNLQ 1057
++ +++L+ W+ + YRL + G+ G V + Y L
Sbjct: 206 VKDIGISTKANSLLISWSHGSGNVERYRLMLMDKGILVHGGV----VDKHATSYAFHGLT 261
Query: 1058 PASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKL 1117
P Y ++++ ++ + V T S++ N + + T++ + W P
Sbjct: 262 PGYLYNLTVMTEAAGLQNYRWKLVRTAPMEVSNLKVTN-DGSLTSLKVKWQRPPGNVDSY 320
Query: 1118 GVRPSQGG--EAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLS 1175
+ S G + R + L PG Y T+ + V +
Sbjct: 321 NITLSHKGTIKESRVLAPWITETHFKELVPGRLYQVTVSCVSGELSAQKMAVGRTF---- 376
Query: 1176 PPTNLHLEANPDTGV--LTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCT 1233
P +LEAN + + L VSW D YRI L V +++
Sbjct: 377 PDKVANLEANNNGRMRSLVVSWS-PPAGDWEQYRILLF---NDSVVLLNITVGKEETQYV 432
Query: 1234 FDN--LSPGLEYNVSVYTVKDD-KESVPISDTIIPEVPQLTDLSFVDITDSSIGLRW-TP 1289
D+ L PG +Y V V + K S +P + L ++S+ + W TP
Sbjct: 433 MDDTGLVPGRQYEVEVIVESGNLKNSERCQGRTVPLA--VLQLRVKHANETSLSIMWQTP 490
Query: 1290 LNSSTIIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAP 1349
+ + + A + + + +T T L PG Y ++ +T I+G
Sbjct: 491 VAEWE----KYIISLADRDLLLIHKSLSKDAKEFTFTDLVPGRKY-MATVTSISGDLKNS 545
Query: 1350 TTLTQQTAVPPPTDLRFTNIGPDTMRVT-WAPPPS-IDLTNFLVRYSPV--KNEEDVAEL 1405
+++ +T TDL N G + T W ++ L+ + V KNE
Sbjct: 546 SSVKGRTVPAQVTDLHVANQGMTSSLFTNWTQAQGDVEFYQVLLIHENVVIKNE------ 599
Query: 1406 SISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSF 1465
SIS + +L G+ Y V V++V S + +T S +G+ ++ N +
Sbjct: 600 SISSETSRYSFHSLKSGSLYSVVVTTVSGGISSRQVVVEGRTVPSSVSGVTVNNSGRNDY 659
Query: 1466 -TVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNG 1524
+V W+ + Y + H + + S + ++LTPG Y V+I +G
Sbjct: 660 LSVSWLLAPGDVDNYEVTL--SHDGKVVQSLVIAKSVRECSFSSLTPGRLYTVTITTRSG 717
Query: 1525 REESPLLIGQQSTVSDVPRDLEVV-AATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQ 1583
+ E+ Q+ TV D + + V +A L +SW +Y +T N+ +Q
Sbjct: 718 KYENHSF-SQERTVPDKVQGVSVSNSARSDYLRVSWVHATGDFDHYEVTIKNK--NNFIQ 774
Query: 1584 EFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTD 1643
++P S++ L PG Y++TV +G+ ++ N RT + + + +
Sbjct: 775 TKSIPKSENECVFVQLVPGRLYSVTVTTKSGQYEANEQG-----NGRTIPEPVKDLTLRN 829
Query: 1644 VQDNSISVKWLPSSSPVTGYRVT---TTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYV 1700
+ V W ++ V Y + K P TA TE L P +Y
Sbjct: 830 RSTEDLHVTWSGANGDVDQYEIQLLFNDMKVFPPFHLVNTA----TEYRFTSLTPGRQYK 885
Query: 1701 VSVYAQNPSGESQPLVQ-----TAVTNID-RPKGLAFTDVDVDSIKIAWESPQGQVSRYR 1754
+ V + + ++ +AV NI P G DS+ + W G V Y
Sbjct: 886 ILVLTISGDVQQSAFIEGFTVPSAVKNIHISPNGAT------DSLTVNWTPGGGDVDSYT 939
Query: 1755 VTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIP 1814
V+ + E T L G +Y + + ++ +++Q I +P
Sbjct: 940 VSAFRHSQKVDSQTIPKHVFEHT--FHRLEAGEQYQIMIASVSGSLKNQ--INVVGRTVP 995
Query: 1815 APTD--LKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSG 1872
A + + SL W Y + + E ++ + +
Sbjct: 996 ASVQGVIADNAYSSYSLIVSWQKAAGVAERYDILLLT-ENGILLRNTSEPATTKQHKFED 1054
Query: 1873 LMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETI 1932
L KY++ + + L S+ AQ T+ + R+T+ + ++ W +
Sbjct: 1055 LTPGKKYKIQILTVSGGLFSKEAQTEGRTVP--AAVTDLRITENSTRHLSFRWTASEGEL 1112
Query: 1933 TGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDAST 1992
+ + + +G + + P V+S++ L G YK+ + T + S+ I T
Sbjct: 1113 SWYNIFLYNPDGNLQERAQVDPLVQSFSFQNLLQGRMYKMVIVT-HSGELSNESFIFGRT 1171
Query: 1993 AIDAPSNLRFL-ATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATI 2051
+ S+LR T +SL +W P Y + P +E +TE
Sbjct: 1172 VPASVSHLRGSNRNTTDSLWFNWSPASGDFDFYELILYNPNGTKKE--NWKDKDLTEWRF 1229
Query: 2052 TGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELPQLVT 2090
GL PG +Y ++V+ + ++ + P L++
Sbjct: 1230 QGLVPGRKYVLWVVTHSGDLSNKVTAESRTAPSPPSLMS 1268
Score = 35.4 bits (80), Expect = 0.70
Identities = 37/194 (19%), Positives = 76/194 (39%), Gaps = 25/194 (12%)
Query: 628 IQWNAPQP-SHISKYILRWRPKNSV---GRWKEATIPGHLNSYTIKGLKPGVVYEGQLIS 683
I W P + + + L+W P++++ + G + + GL+PG Y+ + +
Sbjct: 1279 ITWKGPPDWTDYNDFELQWLPRDALTVFNPYNNRKSEGRI----VYGLRPGRSYQFNVKT 1334
Query: 684 IQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSA 743
+ + ++ F + T N L ++ T I S W+
Sbjct: 1335 VSGDSWKTYSKPIFGSVRTKPDKIQN-----------LHCRPQNSTAIACS-----WIPP 1378
Query: 744 SDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLIL 803
G+ +E + + L + +NI L+P ++Y+V++ ++ G S ++
Sbjct: 1379 DSDFDGYSIECRKMDTQEVEFSRKLEKEKSLLNIMMLVPHKRYLVSI-KVQSAGMTSEVV 1437
Query: 804 STSQTTAPDAPPDP 817
S T D PP P
Sbjct: 1438 EDSTITMIDRPPPP 1451
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 175 bits (443), Expect = 6e-43
Identities = 375/1615 (23%), Positives = 611/1615 (37%), Gaps = 226/1615 (13%)
Query: 630 WNAPQPSHISK---YILRWRPKNSVG--RWKEA--TIPGHLNSYTIKGLKPGVVYEGQLI 682
W+AP SK YI+ +P + VG RW + TI N +T+ L G YE +++
Sbjct: 28959 WSAPAYDGGSKVVGYIIERKPVSEVGDGRWLKCNYTIVSD-NFFTVTALSEGDTYEFRVL 29017
Query: 683 SIQQYGHQEVTRFDFTTTSTST-PVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWV 741
+ G + S ST PVT + VT S V+
Sbjct: 29018 AKNAAGV-------ISKGSESTGPVTCRDEYAPPKAELDARLHGDLVTIRAGSDLVL--- 29067
Query: 742 SASDTVSGFRVEYELS-EEGDEP---------QYLDLPSTATSVNIPDLLPGRKYIVNVY 791
D G + E ++ +GD+ QY +TA + D KY + V
Sbjct: 29068 ---DAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAV-IKFCDRSDSGKYTLTVK 29123
Query: 792 QISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ----APITGYRIVYSP 847
S G +++ + +P TV +V + WS PQ A IT Y +
Sbjct: 29124 NAS--GTKAVSVMVKVLDSPGPCGKLTVSRVTQEKCTLAWSLPQEDGGAEITHYIVERRE 29181
Query: 848 S-------VEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG 900
+ VEG L S ++ L +Y + AV + PV + E
Sbjct: 29182 TSRLNWVIVEGECPTL-------SYVVTRLIKNNEYIFRVRAVNKYGPGVPV--ESEPIV 29232
Query: 901 TPRSDTVPSPRDL-QFVEVTDVKVTIMWTPPES----AVTGYRVDVIPV-NLPGEHGQRL 954
S T+PSP + + V + I WT PES ++ Y VD +L +
Sbjct: 29233 ARNSFTIPSPPGIPEEVGTGKEHIIIQWTKPESDGGNEISNYLVDKREKKSLRWTRVNKD 29292
Query: 955 PISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNL-------QFVN 1007
+ +T +VT L G Y F+V AV+ S+P A P+ + V+
Sbjct: 29293 YVVYDTRLKVTSLMEGCDYQFRVTAVNAAGNSEPSEASNFISCREPSYTPGPPSAPRVVD 29352
Query: 1008 ETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSV--SKYPLRNLQPASE 1061
T ++ + WT P I GY L + Q + + ++ +++ + +L+ +
Sbjct: 29353 TTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDTDQWYRVHTNATIRNTEFTVPDLKMGQK 29412
Query: 1062 YT--VSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGV 1119
Y+ V+ V +KG E ++ ++P I + E+ + + T R G L +
Sbjct: 29413 YSFRVAAVNVKGMSEYSES---IAEIEPVERIEIPDLELADD---LKKTVTIRAGASLRL 29466
Query: 1120 RPSQGGEAPREVT-----SDSGSIVVSGLTPGVEYV------------YTIQVLRDGQER 1162
S G P +T D S + T + YTI+ ++
Sbjct: 29467 MVSVSGRPPPVITWSKQGIDLASRAIIDTTESYSLLIVDKVNRYDAGKYTIEAENQSGKK 29526
Query: 1163 DAPIVNKVV-TPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSL 1221
A ++ KV TP P+ E + D+ +T++WE P I G P N
Sbjct: 29527 SATVLVKVYDTPGPCPSVKVKEVSRDS--VTITWE---IPTIDG----GAPVNNYIVEKR 29577
Query: 1222 EEVVHA-----DQSSCTFDNLSPGLEYNVSVYTVKDDK-----ESVPISDTI-IPEVPQL 1270
E + A + S T +S +E + + V + E SD + + EVP +
Sbjct: 29578 EAAMRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYGIGEPCETSDAVLVSEVPLV 29637
Query: 1271 -TDLSFVDITDSSIGLRW-TPL--NSSTIIGYRITVVAAGEGIPIFEDFVDSSVGYYTVT 1326
L VD+T S++ L W PL S + GY + AG + + +V +TVT
Sbjct: 29638 PAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGTERWMKVVTLKPTVLEHTVT 29697
Query: 1327 GLEPGIDYDISVITLINGGESAP----TTLT-QQTAVPPPTDLRFTNIGPDTMRV----- 1376
L G Y + G S P T +T Q V P DL + + T+ V
Sbjct: 29698 SLNEGEQYLFRIRAQNEKGVSEPRETVTAVTVQDLRVLPTIDL--STMPQKTIHVPAGRP 29755
Query: 1377 -------TWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSV 1429
PPP+ F ++E E + + T + EY + +
Sbjct: 29756 VELVIPIAGRPPPAASW--FFAGSKLRESERVTVETHTKVAKLTIRETTIRDTGEYTLEL 29813
Query: 1430 SSVY-EQHESTPLRGRQKTGLDSPTG-IDFSDITANSFTVHWIAPR----ATITGYRIRH 1483
+V E+ + K G PTG I +I A S T+ W P A ++GY +
Sbjct: 29814 KNVTGTTSETIKVIILDKPG--PPTGPIKIDEIDATSITISWEPPELDGGAPLSGYVVEQ 29871
Query: 1484 HPEHFSG-RPREDRVPHSRNSITLTNLTPGTEYVVSIVALN----GREESPLLIGQQST- 1537
H G P + V +R++ T LT G EYV + A N G +I +S+
Sbjct: 29872 RDAHRPGWLPVSESV--TRSTFKFTRLTEGNEYVFRVAATNRFGIGSYLQSEVIECRSSI 29929
Query: 1538 -VSDVPRDLEVVAATPTSLLISWDAP----AVTVRYYRITYGETGGNSPVQEFTVPGSKS 1592
+ P L++ + + ++W P V Y + E + V+ VP + +
Sbjct: 29930 RIPGPPETLQIFDVSRDGMTLTWYPPEDDGGSQVTGYIVERKEVRADRWVRVNKVPVTMT 29989
Query: 1593 TATISGLKPGVDYTITVYAVTGRGDSPAS--SKPI-SINYRTEIDKPSQMQVTDVQDNSI 1649
+GL G++Y V A+ RG S SKPI +++ KP +VTD S+
Sbjct: 29990 RYRSTGLTEGLEYEHRVTAINARGSGKPSRPSKPIVAMDPIAPPGKPQNPRVTDTTRTSV 30049
Query: 1650 SVKWL----PSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYA 1705
S+ W S VTGY + + TK T E T+ L EY V A
Sbjct: 30050 SLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTKCNTTPTKIREYTLTHLPQGAEYRFRVLA 30109
Query: 1706 QNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDS-IKIAWESPQGQVSRYRVTYSSPEDGI 1764
N G +P + + L + D ++D + QG V R + I
Sbjct: 30110 CNAGGPGEPAEVPGTVKV--TEMLEYPDYELDERYQEGIFVRQGGVIRLTIPIKGKPFPI 30167
Query: 1765 HELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMES------------QPLIGTQSTA 1812
+ +G +D ++ + +T V+ D +S + + +
Sbjct: 30168 CKW--TKEG-QDISKRAMIATSETHTELVIKEADRGDSGTYDLVLENKCGKKAVYIKVRV 30224
Query: 1813 IPAPTD----LKFTQVTPTSLSAQWTPP----NVQLTGYRV--RVTPKEKTGPMKEINLA 1862
I +P L++ + S+ W PP + GY + R PK I+
Sbjct: 30225 IGSPNSPEGPLEYDDIQVRSVRVSWRPPADDGGADILGYILERREVPK---AAWYTIDSR 30281
Query: 1863 PDSSSVVVSGLMVATKYEVSVYALKDTLTSRP--AQGVVTTLENVSPP----RRARVTDA 1916
+S+VV GL +Y V A S+P ++ VT ++PP V D
Sbjct: 30282 VRGTSLVVKGLKENVEYHFRVSAENQFGISKPLKSEEPVTPKTPLNPPEPPSNPPEVLDV 30341
Query: 1917 TETTITISW-RTKTE---TITGFQVDAVPANGQTPIQRT-IKPDVRSYTITGLQPGTDYK 1971
T++++++SW R K + +TG+ ++ + ++ + YT+TGL P +Y+
Sbjct: 30342 TKSSVSLSWSRPKDDGGSRVTGYYIERKETSTDKWVRHNKTQITTTMYTVTGLVPDAEYQ 30401
Query: 1972 IYLYTLND------NARSSPVVI-DASTAIDAPSNLRFLATTPNSLLVSWQPPRA----R 2020
+ ND + S PVV D P L L+ + +S+ + W+ P
Sbjct: 30402 FRIIAQNDVGLSETSPASEPVVCKDPFDKPSQPGELEILSISKDSVTLQWEKPECDGGKE 30461
Query: 2021 ITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEP 2075
I GY ++Y + G + + R + TI GL TEY V A S P
Sbjct: 30462 ILGYWVEYRQSGDSAWKKSNKERIKDKQFTIGGLLEATEYEFRVFAENETGLSRP 30516
Score = 147 bits (371), Expect = 1e-34
Identities = 366/1672 (21%), Positives = 605/1672 (36%), Gaps = 240/1672 (14%)
Query: 612 VEVFITETPSQPNSHPIQ----------WNAPQP---SHISKYILRWRPKNSVGRWKEAT 658
VEV + + P P + I WN P+ S I+ Y++ R +S W + +
Sbjct: 13776 VEVNVLDKPGPPAAFDITDVTNESCLLTWNPPRDDGGSKITNYVVERRATDSEV-WHKLS 13834
Query: 659 IPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPF 718
++ L P Y ++ + YG E PV ++ +T +
Sbjct: 13835 STVKDTNFKATKLIPNKEYIFRVAAENMYGVGE-------------PVQASPITAKYQFD 13881
Query: 719 SPLVATSESVTEITASSFVVSWVSASDT----VSGFRVEYELSEEGDEPQYLDLPSTATS 774
P T ++IT + ++W D ++G+ VE + + +P T+
Sbjct: 13882 PPGPPTRLEPSDITKDAVTLTWCEPDDDGGSPITGYWVERLDPDTDKWVRCNKMPVKDTT 13941
Query: 775 VNIPDLLPGRKYIVNVY--QISEDGEQSL----ILSTSQTTAPDAPPDPTVDQVDDTSIV 828
+ L +KY V ++ G+ S IL P P PTV V TS+
Sbjct: 13942 YRVKGLTNKKKYRFRVLAENLAGPGKPSKSTEPILIKDPIDPPWPPGKPTVKDVGKTSVR 14001
Query: 829 VRWSRPQ----APITGY--RIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYA 882
+ W++P+ A I Y ++ + + E +P T + L L G +Y+ + A
Sbjct: 14002 LNWTKPEHDGGAKIESYVIEMLKTGTDEWVRVAEGVPTTQH--LLPGLMEGQEYSFRVRA 14059
Query: 883 VEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYR 938
V + ES P + PR L+ + +T + WT PE S +T Y
Sbjct: 14060 VNKAGESEPSEPSDPVLCREKLYPPSPPRWLEVINITKNTADLKWTVPEKDGGSPITNYI 14119
Query: 939 VDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSH-GR------ESKPLTA 991
V+ V G + ++T VT L+ G Y F+V A + G+ E L
Sbjct: 14120 VEKRDVRRKGWQTVDTTV-KDTKCTVTPLTEGSLYVFRVAAENAIGQSDYTEIEDSVLAK 14178
Query: 992 QQTTKLDAPTNLQFVNETDSTVLVRWTPPR--AQITGYRLTVGLTRRGQPRQYNVGPSVS 1049
T P L V+ T V ++W PP+ R + R R G +
Sbjct: 14179 DTFTTPGPPYALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKERLGTRWVKAGKTAG 14238
Query: 1050 KYPLRNLQPASEYTVSLVAIKGNQES-----PKATGVFTTLQPGS-SIPPYNTEVTET-- 1101
+ E T ++ E+ + T + + P S PP + VT+
Sbjct: 14239 PDCNFRVTDVIEGTEVQFQVRAENEAGVGHPSEPTEILSIEDPTSPPSPPLDLHVTDAGR 14298
Query: 1102 -TIVITWTP------APRIGFKLGVRPSQGGEAPREVTS----DSGSIVVSGLTPGVEYV 1150
I I W P +P IG+ + + P G E V S D V G+ P EYV
Sbjct: 14299 KHIAIAWKPPEKNGGSPIIGYHVEMCP-VGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYV 14357
Query: 1151 YTIQVLRD-GQERDAPIVNKVVT--PLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYR 1207
++ + G + I VV P PT + LE + ++ + E+ + P +R
Sbjct: 14358 LRVRAVNAIGVSEPSEISENVVAKDPDCKPT-IDLETH---DIIVIEGEKLSIP--VPFR 14411
Query: 1208 ITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEY------NVSVYTV----KDDKESV 1257
PT + +EV +D+ + D++S LE + +YT+ K +
Sbjct: 14412 AVPVPTVSWHKDG-KEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATA 14470
Query: 1258 PISDTIIPEVPQLTDLSFVDITDSSIGLRWTPL---NSSTIIGYRITVVAAGEG--IPIF 1312
I+ +I D+ DIT SS L W P + I+ Y + AG IP+
Sbjct: 14471 SINVKVIGLPGPCKDIKASDITKSSCKLTWEPPEFDGGTPILHYVLERREAGRRTYIPVM 14530
Query: 1313 EDFVDSSVGYYTVTGLEPGIDY--DISVITLINGGESAP---TTLTQQTAVP--PPTDLR 1365
S +TV L P +Y + + + GGE + Q P PP D+
Sbjct: 14531 SGENKLS---WTVKDLIPNGEYFFRVKAVNKVGGGEYIELKNPVIAQDPKQPPDPPVDVE 14587
Query: 1366 FTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLT----NLLP 1421
N + M +TW PP D + ++ Y K + +LT L
Sbjct: 14588 VHNPTAEAMTITW-KPPLYDGGSKIMGYIIEKIAKGEERWKRCNEHLVPILTYTAKGLEE 14646
Query: 1422 GTEYVVSVSSVYEQHESTPLRGRQKT----GLDSP---------------TGIDFSDITA 1462
G EY V + S P R T +D+P +D S +
Sbjct: 14647 GKEYQFRVRAENAAGISEPSRATPPTKAVDPIDAPKVILRTSLEVKRGDEIALDASISGS 14706
Query: 1463 NSFTVHWIAPRATITGYRIRHHPEHFSGRPR------EDRVPHSRNSITLTNLTPGTE-- 1514
T+ WI I I+ R + E V +++ N G
Sbjct: 14707 PYPTITWIKDENVIVPEEIKKRAAPLVRRRKGEVQEEEPFVLPLTQRLSIDNSKKGESQL 14766
Query: 1515 ------------YVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAP 1562
Y++ + +G ++P + T P + TS+L W+ P
Sbjct: 14767 RVRDSLRPDHGLYMIKVENDHGIAKAPCTVSVLDTPGP-PINFVFEDIRKTSVLCKWEPP 14825
Query: 1563 -----AVTVRYYRITYGETGGNSPVQEFTVPGS---KSTATISGLKPGVDYTITVYAVTG 1614
+ + Y T + P E+ V S +++ L G +Y V A
Sbjct: 14826 LDDGGSEIINY---TLEKKDKTKPDSEWIVVTSTLRHCKYSVTKLIEGKEYLFRVRAENR 14882
Query: 1615 RGDS-PASSKP-ISINYRTEIDKPSQMQVTDVQDNSISVKW---LPSSSPVTGYRVTTTP 1669
G P SKP ++ + D P + V DV NS+ VKW + SP+ GY +
Sbjct: 14883 FGPGPPCVSKPLVAKDPFGPPDAPDKPIVEDVTSNSMLVKWNEPKDNGSPILGYWLEKRE 14942
Query: 1670 KNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSG------ESQPLVQTAVTNI 1723
N ++ + + + ++GL + YV V A+N +G S P +
Sbjct: 14943 VNSTHWSRVNKSLLNALKANVDGLLEGLTYVFRVCAENAAGPGKFSPPSDPKTAHDPISP 15002
Query: 1724 DRPKGLAFTDVDVDSIKIAWESPQ----GQVSRYRVTYSSPEDGIHELFPAPDGEEDTAE 1779
P TD +I++ WE P G++ Y V G +E + +
Sbjct: 15003 PGPPIPRVTDTSSTTIELEWEPPAFNGGGEIVGYFV--DKQLVGTNEWSRCTEKMIKVRQ 15060
Query: 1780 --LQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPN 1837
++ +R G++Y + V A++ E P TQ + P + ++ +
Sbjct: 15061 YTVKEIREGADYKLRVSAVNAAGEGPP-GETQPVTVAEPQEPPAVELDVS------VKGG 15113
Query: 1838 VQLTGYRVRVTPKEKTG---PMKEINLAP---DSSSVVVSGLMVATKYEVSVYALKDTLT 1891
+Q+ + P TG P K D VV+ V TK E+ +KD L
Sbjct: 15114 IQIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKDRVVIDN--VGTKSEL---IIKDALR 15168
Query: 1892 SRPAQGVVTTLENVS---PPRRARVTDATETTI------------TISWRTKTE----TI 1932
+ V+T + R V D + ++W + I
Sbjct: 15169 KDHGRYVITATNSCGSKFAAARVEVFDVPGPVLDLKPVVTNRKMCLLNWSDPEDDGGSEI 15228
Query: 1933 TGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDAST 1992
TGF ++ A T ++ I+ + ITGL G +YK + N PV I
Sbjct: 15229 TGFIIERKDAKMHT-WRQPIETERSKCDITGLLEGQEYKFRVIAKNKFGCGPPVEIGPIL 15287
Query: 1993 AID------APSNLRFLATTPNSLLVSWQPPRAR----ITGYIIKYEKPGSPPREVVPRP 2042
A+D +P L + T +++ + W+ PR+ I GYII+ + P E V +
Sbjct: 15288 AVDPLGPPTSPERLTYTERTKSTITLDWKEPRSNGGSPIQGYIIEKRRHDKPDFERVNKR 15347
Query: 2043 RPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRK---KTDELPQLVTL 2091
T + L+ Y V A+ +SEP + + DE+P + L
Sbjct: 15348 LCPTTSFLVENLDEHQMYEFRVKAVNEIGESEPSLPLNVVIQDDEVPPTIKL 15399
Score = 144 bits (362), Expect = 1e-33
Identities = 288/1427 (20%), Positives = 522/1427 (36%), Gaps = 163/1427 (11%)
Query: 696 DFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYE 755
D+T T+ ++ + + P S + ++ + ++SW + Y
Sbjct: 19365 DYTITAENSSGSKSATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYI 19424
Query: 756 LSE-EGDEPQYLDLPSTA--TSVNIPDLLPGRKY-----IVNVYQISEDGEQSLILSTSQ 807
+ + E P + + +T TS ++ L+ G +Y N Y + + ++ +
Sbjct: 19425 VDKRETSRPNWAQVSATVPITSCSVEKLIEGHEYQFRICAENKYGVGDPVFTEPAIAKNP 19484
Query: 808 TTAPDAPPDPTVDQVDDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNL-PETA 862
P P + + + V W P +PITGY + + + T++N P
Sbjct: 19485 YDPPGRCDPPVISNITKDHMTVSWKPPADDGGSPITGYLLEKRETQAVNWTKVNRKPIIE 19544
Query: 863 NSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVK 922
++ + LQ G +Y + A+ + P + P + + T
Sbjct: 19545 RTLKATGLQEGTEYEFRVTAINKAGPGKPSDASKAAYARDPQYPPGPPAFPKVYDTTRSS 19604
Query: 923 VTIMWTPPE----SAVTGYRVDVIPVNLPGEHGQRLPIS-RNTFAEVTGLSPGVTYYFKV 977
V++ W P S + GY V+V + LP + + T EVTGL Y F+V
Sbjct: 19605 VSLSWGKPAYDGGSPIIGYLVEVKRADSDNWVRCNLPQNLQKTRFEVTGLMEDTQYQFRV 19664
Query: 978 FAVSHGRESKP-----------LTAQQTTKLDAPTNLQFVNETDST----VLVRWTPPRA 1022
+AV+ S P + +LDA + T V V+ PP
Sbjct: 19665 YAVNKIGYSDPSDVPDKHYPKDILIPPEGELDADLRKTLILRAGVTMRLYVPVKGRPP-P 19723
Query: 1023 QITGYRLTVGLTRR-GQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGV 1081
+IT + V L R G + + + N A +Y ++L G +E V
Sbjct: 19724 KITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKYILTLENSCGKKEYTIVVKV 19783
Query: 1082 FTTLQPGSSIPPYNTEVTETTIVITWTP------APRIGFKLGVRPSQGGEAPREVTSDS 1135
T PG + E+++ + +TW P +P I + + R ++ T S
Sbjct: 19784 LDT--PGPPVNVTVKEISKDSAYVTWEPPIIDGGSPIINYVVQKRDAERKSWSTVTTECS 19841
Query: 1136 -GSIVVSGLTPGVEYVYTIQVLRD------GQERDAPIVNKVVTPLSPPTNLHLEANPDT 1188
S V+ L G Y + + + G+ RDA V TP P +L + + +
Sbjct: 19842 KTSFRVANLEEGKSYFFRVFAENEYGIGDPGETRDA--VKASQTP-GPVVDLKVRSVSKS 19898
Query: 1189 GVLTVSWERSTTPD---ITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNV 1245
++ W++ + I GY + + N + V+ + + +L+ G EY
Sbjct: 19899 S-CSIGWKKPHSDGGSRIIGYVVDFL----TEENKWQRVMKSLSLQYSAKDLTEGKEYTF 19953
Query: 1246 SVYTVKDDKESVPISDTIIP---------EVPQLTDLSFVDITDSSIGLR---------- 1286
V ++ E P T++ ++ L DL ++ +S+ L+
Sbjct: 19954 RVSAENENGEGTPSEITVVARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPIKGKPAPS 20013
Query: 1287 --WTPLNSSTIIGYRITVVAAGEGIP-IFEDFVDSSVGYYTVTGLEPGIDYDISVITLIN 1343
W R++V ++ I D S G YT+T + ++ +
Sbjct: 20014 VSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKEGTISIKVV 20073
Query: 1344 GGESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAPPP---SIDLTNFLVRYSPVKNEE 1400
G PT ++F + + M + WAPP ++TN+++ N +
Sbjct: 20074 GKPGIPT-----------GPIKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDSVNNK 20122
Query: 1401 DVAELSISPSDNAVVLTNLLPGTEYVVSVSS-----VYEQHESTPLRGRQKTGL-DSPTG 1454
V S + +T L G EY VS+ V E +S P+ R + D+P
Sbjct: 20123 WVTCAS-AVQKTTFRVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVPDAPPP 20181
Query: 1455 IDFSDITANSFTVHWIAPRAT----ITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLT 1510
+ D+ +S ++ W P+ T ITGY + + R ++ P +T LT
Sbjct: 20182 PNIVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTPIRMRDFKVTGLT 20241
Query: 1511 PGTEYVVSIVALN----GREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAV-- 1564
G EY ++A+N G+ P D P EV+ T S+ + W P
Sbjct: 20242 EGLEYEFRVMAINLAGVGKPSLPSEPVVALDPIDPPGKPEVINITRNSVTLIWTEPKYDG 20301
Query: 1565 --TVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASS 1622
+ Y + + S ++ V + T++ L G Y + A G A S
Sbjct: 20302 GHKLTGYIVEKRDLPSKSWMKANHVNVPECAFTVTDLVEGGKYEFRIRAKNTAGAISAPS 20361
Query: 1623 KPI-SINYRTEIDKPSQMQVTDVQD------------NSISV--KWLPSSS-PVTGYRVT 1666
+ +I + E + P+ + ++D N+IS+ K LP SS G +
Sbjct: 20362 ESTETIICKDEYEAPTIVLDPTIKDGLTIKAGDTIVLNAISILGKPLPKSSWSKAGKDIR 20421
Query: 1667 TTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRP 1726
P T+ P + +TI+ ++ A NP G V+ V ++ P
Sbjct: 20422 ------PSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFGTKVEHVKVTVLDVPGP 20475
Query: 1727 KG-LAFTDVDVDSIKIAWESP---QGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQG 1782
G + ++V + + W P G + + + + D +
Sbjct: 20476 PGPVEISNVSAEKATLTWTPPLEDGGSPIKSYILEKRETSRLLWTVVSEDIQSCRHVATK 20535
Query: 1783 LRPGSEYTVSVVALH-----DDMESQPLIGTQSTAIPAPTDL-KFTQVTPTSLSAQWTPP 1836
L G+EY V A++ + ++S+P+ P P + + + VT + + W P
Sbjct: 20536 LIQGNEYIFRVSAVNHYGKGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSWKRP 20595
Query: 1837 ----NVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTS 1892
++TGY V K+ ++ I V+GL + YE V A
Sbjct: 20596 VDDGGSEITGYHVERREKKSLRWVRAIKTPVSDLRCKVTGLQEGSTYEFRVSAENRAGIG 20655
Query: 1893 RPAQGVVTTLEN-----VSPPRRARVTDATETTITISWRTKTE----TITGFQVDAVPAN 1943
P++ + L PP VTD T+ + +++W ITG+ V+
Sbjct: 20656 PPSEASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLAWGKPHYDGGLEITGYVVEHQKVG 20715
Query: 1944 GQTPIQRTIKPDVR--SYTITGLQPGTDYKIYLYTLNDNARSSPVVI 1988
+ I+ T +R + + LQ Y + +ND P VI
Sbjct: 20716 DEAWIKDTTGTALRITQFVVPDLQTKEKYNFRISAINDAGVGEPAVI 20762
Score = 136 bits (342), Expect = 3e-31
Identities = 287/1435 (20%), Positives = 516/1435 (35%), Gaps = 196/1435 (13%)
Query: 794 SEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ----APITGYRIVYSPSV 849
+ G +S + P P ++++ ++ W P + IT Y + +
Sbjct: 19372 NSSGSKSATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYIVDKRETS 19431
Query: 850 EGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPS 909
+ +++ S ++ L G +Y I A + PV + P P
Sbjct: 19432 RPNWAQVSATVPITSCSVEKLIEGHEYQFRICAENKYGVGDPVFTEPAIAKNPYDP--PG 19489
Query: 910 PRDLQFVE-VTDVKVTIMWTPPE----SAVTGYRVDVIPVNLPG-EHGQRLPISRNTFAE 963
D + +T +T+ W PP S +TGY ++ R PI T +
Sbjct: 19490 RCDPPVISNITKDHMTVSWKPPADDGGSPITGYLLEKRETQAVNWTKVNRKPIIERTL-K 19548
Query: 964 VTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKL-------DAPTNLQFVNETDSTVLVR 1016
TGL G Y F+V A++ KP A + P + + T S+V +
Sbjct: 19549 ATGLQEGTEYEFRVTAINKAGPGKPSDASKAAYARDPQYPPGPPAFPKVYDTTRSSVSLS 19608
Query: 1017 WTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSVSK--YPLRNLQPASEYTVSLVAIK 1070
W P + I GY + V + N+ ++ K + + L ++Y + A+
Sbjct: 19609 WGKPAYDGGSPIIGYLVEVKRADSDNWVRCNLPQNLQKTRFEVTGLMEDTQYQFRVYAVN 19668
Query: 1071 GNQESPKATGVFTTLQPGSSIPP---YNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEA 1127
S + IPP + ++ +T I+ R G + + G
Sbjct: 19669 KIGYSDPSDVPDKHYPKDILIPPEGELDADLRKTLIL-------RAGVTMRLYVPVKGRP 19721
Query: 1128 PREVTSDSGSIVVS---GLT------------------PGVEYVYTIQVLRDGQERDAPI 1166
P ++T ++ + GL +Y+ T++ +++ I
Sbjct: 19722 PPKITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKYILTLE--NSCGKKEYTI 19779
Query: 1167 VNKVVTPLSPPTNLHL-EANPDTGVLTVSWERSTTPDITG----YRITTTPTNGQQGNSL 1221
V KV+ PP N+ + E + D+ +T WE P I G + ++ +
Sbjct: 19780 VVKVLDTPGPPVNVTVKEISKDSAYVT--WE---PPIIDGGSPIINYVVQKRDAERKSWS 19834
Query: 1222 EEVVHADQSSCTFDNLSPGLEYNVSVYTVKD--------DKESVPISDTIIPEVPQLTDL 1273
++S NL G Y V+ + +++V S T P V DL
Sbjct: 19835 TVTTECSKTSFRVANLEEGKSYFFRVFAENEYGIGDPGETRDAVKASQTPGPVV----DL 19890
Query: 1274 SFVDITDSSIGLRWTPLNS---STIIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEP 1330
++ SS + W +S S IIGY + + ++ + S Y+ L
Sbjct: 19891 KVRSVSKSSCSIGWKKPHSDGGSRIIGYVVDFLTEENK---WQRVMKSLSLQYSAKDLTE 19947
Query: 1331 GIDYDISVITLINGGESAPTTLT---QQTAVPPPTDLRFTNIGPDT-------------M 1374
G +Y V GE P+ +T + V P DL+ PD +
Sbjct: 19948 GKEYTFRVSAENENGEGTPSEITVVARDDVVAPDLDLKGL---PDLCYLAKENSNFRLKI 20004
Query: 1375 RVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLL-------PGTEYVV 1427
+ P PS+ S K E+ +A + +++ V T L+ +Y +
Sbjct: 20005 PIKGKPAPSV---------SWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTI 20055
Query: 1428 SVSSVYEQHEST-PLRGRQKTGLDSPTG-IDFSDITANSFTVHWIAPR----ATITGYRI 1481
++ +V E T ++ K G+ PTG I F ++TA + T+ W P+ + IT Y I
Sbjct: 20056 TLKNVAGTKEGTISIKVVGKPGI--PTGPIKFDEVTAEAMTLKWAPPKDDGGSEITNY-I 20112
Query: 1482 RHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN------GREESPLLIGQQ 1535
+ + + + + +T L G EY + A N G + P++
Sbjct: 20113 LEKRDSVNNKWVTCASAVQKTTFRVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHP 20172
Query: 1536 STVSDVPRDLEVVAATPTSLLISWDAPAVT----VRYYRITYGETGGNSPVQEFTVPGSK 1591
V D P +V S+ ++W P T + Y + + E + P
Sbjct: 20173 FDVPDAPPPPNIVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTPIRM 20232
Query: 1592 STATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISV 1651
++GL G++Y V A+ G S + ID P + +V ++ NS+++
Sbjct: 20233 RDFKVTGLTEGLEYEFRVMAINLAGVGKPSLPSEPVVALDPIDPPGKPEVINITRNSVTL 20292
Query: 1652 KWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQN 1707
W +TGY V K + T+ L +Y + A+N
Sbjct: 20293 IWTEPKYDGGHKLTGYIVEKRDLPSKSWMKANHVNVPECAFTVTDLVEGGKYEFRIRAKN 20352
Query: 1708 PSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQV----------------S 1751
+G ++ T I + + A T V +IK G S
Sbjct: 20353 TAGAISAPSESTETIICKDEYEAPTIVLDPTIKDGLTIKAGDTIVLNAISILGKPLPKSS 20412
Query: 1752 RYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQST 1811
+ I ++ P T + + EYT++ +
Sbjct: 20413 WSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFGTKVEHVKVTVLDV 20472
Query: 1812 AIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVR--VTPKEKTGPMKEINLAPDSSSV- 1868
P P ++ + V+ + WTPP ++ G ++ + K +T + ++ D S
Sbjct: 20473 PGP-PGPVEISNVSAEKATLTWTPP-LEDGGSPIKSYILEKRETSRLLWTVVSEDIQSCR 20530
Query: 1869 -VVSGLMVATKYEVSVYALKDTLTSRPAQG----VVTTLENVSPPRRARVTDATETTITI 1923
V + L+ +Y V A+ P Q +V PP + V++ T+ T T+
Sbjct: 20531 HVATKLIQGNEYIFRVSAVNHYGKGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTATV 20590
Query: 1924 SWRTKTE----TITGFQVDAVPANGQTPIQRTIKPDVRSY--TITGLQPGTDYKIYLYTL 1977
SW+ + ITG+ V+ + R IK V +TGLQ G+ Y+ +
Sbjct: 20591 SWKRPVDDGGSEITGYHVERREKKSLRWV-RAIKTPVSDLRCKVTGLQEGSTYEFRVSAE 20649
Query: 1978 N-------DNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYII 2026
N A S ++ DA+ PSN TT S ++W P ITGY++
Sbjct: 20650 NRAGIGPPSEASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLAWGKPHYDGGLEITGYVV 20709
Query: 2027 KYEKPGSPPREVVPRPRPG----VTEATITGLEPGTEYTIYVIALKNNQKSEPLI 2077
+++K G E + G +T+ + L+ +Y + A+ + EP +
Sbjct: 20710 EHQKVGD---EAWIKDTTGTALRITQFVVPDLQTKEKYNFRISAINDAGVGEPAV 20761
Score = 134 bits (338), Expect = 9e-31
Identities = 378/1880 (20%), Positives = 675/1880 (35%), Gaps = 278/1880 (14%)
Query: 628 IQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISI 684
+ W P S I+ Y+L R +V K P + GL+ G YE ++ +I
Sbjct: 19506 VSWKPPADDGGSPITGYLLEKRETQAVNWTKVNRKPIIERTLKATGLQEGTEYEFRVTAI 19565
Query: 685 QQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSW---- 740
+ G + + S + P V + T SS +SW
Sbjct: 19566 NKAGPGKPSD------------ASKAAYARDPQYPPGPPAFPKVYDTTRSSVSLSWGKPA 19613
Query: 741 VSASDTVSGFRVEYELSEEGDEPQYLDLPST--ATSVNIPDLLPGRKYIVNVYQISEDGE 798
+ G+ VE + + + D +LP T + L+ +Y VY +++ G
Sbjct: 19614 YDGGSPIIGYLVEVKRA-DSDNWVRCNLPQNLQKTRFEVTGLMEDTQYQFRVYAVNKIG- 19671
Query: 799 QSLILSTSQTTAPD--------APPDPTVDQVDDTSIVVR---WSRPQAPITGYRIVYSP 847
+ + PD PP+ +D ++++R R P+ G P
Sbjct: 19672 -----YSDPSDVPDKHYPKDILIPPEGELDADLRKTLILRAGVTMRLYVPVKGRP---PP 19723
Query: 848 SVEGSSTELNLPETAN-SVTLSDLQPGV-----------QYNITIYAVEENQESTPVVIQ 895
+ S +NL + + +D + +Y +T+ +E T VV
Sbjct: 19724 KITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKYILTLENSCGKKEYTIVVKV 19783
Query: 896 QETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPGEHG 951
+T G P + TV E++ + W PP S + Y V
Sbjct: 19784 LDTPGPPVNVTVK--------EISKDSAYVTWEPPIIDGGSPIINYVVQKRDAERKSWST 19835
Query: 952 QRLPISRNTFAEVTGLSPGVTYYFKVFAVSH---GRESKPLTAQQTTKLDAP-TNLQFVN 1007
S+ +F V L G +Y+F+VFA + G + A + ++ P +L+ +
Sbjct: 19836 VTTECSKTSF-RVANLEEGKSYFFRVFAENEYGIGDPGETRDAVKASQTPGPVVDLKVRS 19894
Query: 1008 ETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYT 1063
+ S+ + W P ++I GY + LT + ++ S+ +Y ++L EYT
Sbjct: 19895 VSKSSCSIGWKKPHSDGGSRIIGYVVDF-LTEENKWQRVMKSLSL-QYSAKDLTEGKEYT 19952
Query: 1064 VSLVAIKGNQE-SPKATGVFT---TLQPG---SSIPPYNTEVTETT-----IVITWTPAP 1111
+ A N E +P V + P +P E + I I PAP
Sbjct: 19953 FRVSAENENGEGTPSEITVVARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPIKGKPAP 20012
Query: 1112 RIGFKLGVRP-SQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKV 1170
+ +K G P + E ++ + +++V YTI + ++ I KV
Sbjct: 20013 SVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKEGTISIKV 20072
Query: 1171 VTPLSPPTNLHLEANPDTGVLTVSW---ERSTTPDITGYRITTTPTNGQQGNSLEEVVHA 1227
V PT +T+ W + +IT Y + + + + V
Sbjct: 20073 VGKPGIPTGPIKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDSVNNKWVTCASAV-- 20130
Query: 1228 DQSSCTFDNLSPGLEYNVSV-----YTVKDDKESVPI---SDTIIPEVPQLTDLSFVDIT 1279
+++ L G+EY V Y V + +S PI +P+ P ++ VD+
Sbjct: 20131 QKTTFRVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVPDAPPPPNI--VDVR 20188
Query: 1280 DSSIGLRWT---PLNSSTIIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDI 1336
S+ L WT S I GY + + + + + VTGL G++Y+
Sbjct: 20189 HDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTPIRMRDFKVTGLTEGLEYEF 20248
Query: 1337 SVITLINGGESAPTTLTQQTA----VPPPTDLRFTNIGPDTMRVTWAPPP---SIDLTNF 1389
V+ + G P+ ++ + PP NI +++ + W P LT +
Sbjct: 20249 RVMAINLAGVGKPSLPSEPVVALDPIDPPGKPEVINITRNSVTLIWTEPKYDGGHKLTGY 20308
Query: 1390 LVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEY---------VVSVSSVYEQHESTP 1440
+V + ++ + ++ + A +T+L+ G +Y ++S+ E E+
Sbjct: 20309 IVEKRDLPSKSWMKANHVNVPECAFTVTDLVEGGKYEFRIRAKNTAGAISAPSESTETII 20368
Query: 1441 LRGRQK--TGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVP 1498
+ + T + PT D I A V +I G + P+ + +D P
Sbjct: 20369 CKDEYEAPTIVLDPTIKDGLTIKAGDTIV---LNAISILGKPL---PKSSWSKAGKDIRP 20422
Query: 1499 HSRNSITLTNLT-----------PGTEYVVSIVALNGREESPLLIGQQSTVSDV---PRD 1544
IT T + EY ++ G + + + TV DV P
Sbjct: 20423 SDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFGTKVEHVKV----TVLDVPGPPGP 20478
Query: 1545 LEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATI-------- 1596
+E+ + ++W P E GG SP++ + + +++ +
Sbjct: 20479 VEISNVSAEKATLTWTPPL-----------EDGG-SPIKSYILEKRETSRLLWTVVSEDI 20526
Query: 1597 -------SGLKPGVDYTITVYAVT--GRGDSPASSKPISINYR-TEIDKPSQMQVTDVQD 1646
+ L G +Y V AV G+G+ P S+P+ + R P + +V++V
Sbjct: 20527 QSCRHVATKLIQGNEYIFRVSAVNHYGKGE-PVQSEPVKMVDRFGPPGPPEKPEVSNVTK 20585
Query: 1647 NSISVKWL----PSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVS 1702
N+ +V W S +TGY V K + + GLQ Y
Sbjct: 20586 NTATVSWKRPVDDGGSEITGYHVERREKKSLRWVRAIKTPVSDLRCKVTGLQEGSTYEFR 20645
Query: 1703 VYAQNPSGESQP-------LVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQG----QVS 1751
V A+N +G P L++ A P TD S +AW P +++
Sbjct: 20646 VSAENRAGIGPPSEASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLAWGKPHYDGGLEIT 20705
Query: 1752 RYRVTYSSPEDGIHELFPAPDGEEDTA-ELQGLRPGSEYTVSVVALHDDMESQPLIGTQS 1810
Y V + D T + L+ +Y + A++D +P +
Sbjct: 20706 GYVVEHQKVGDEAWIKDTTGTALRITQFVVPDLQTKEKYNFRISAINDAGVGEPAV---- 20761
Query: 1811 TAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPD------ 1864
IP ++ L A+ V G +R+ K P E+ D
Sbjct: 20762 --IPDVEIVEREMAPDFELDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKN 20819
Query: 1865 ------SSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVT--TLENVSPPRRARVTDA 1916
+ S + + +Y+ + + + G V L+ P R TD
Sbjct: 20820 RANIENTESFTLLIIPECNRYDTGKFVMTIENPAGKKSGFVNVRVLDTPGPVLNLRPTDI 20879
Query: 1917 TETTITISWRTKT----ETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKI 1972
T+ ++T+ W IT + V+ A ++ T K +Y +TGL G +Y
Sbjct: 20880 TKDSVTLHWDLPLIDGGSRITNYIVEKREATRKSYSTATTKCHKCTYKVTGLSEGCEYFF 20939
Query: 1973 YLYTLNDNARSSPV----VIDASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGY 2024
+ N+ P + AS A P +L + T +++ ++W P+ ++ITGY
Sbjct: 20940 RVMAENEYGIGEPTETTEPVKASEAPSPPDSLNIMDITKSTVSLAWPKPKHDGGSKITGY 20999
Query: 2025 IIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDE 2084
+I+ ++ GS + + E + L G EYT V+A+ + +S P R
Sbjct: 21000 VIEAQRKGSDQWTHITTVKG--LECVVRNLTEGEEYTFQVMAVNSAGRSAPRESRPVI-- 21055
Query: 2085 LPQLVTLPHPNLHGPEILDVPSTVQKTPFVTHPGYDTGNGIQLPGTSGQQPSV----GQQ 2140
+ + LP +L G + + + G + +++P +P+V G Q
Sbjct: 21056 VKEQTMLPELDLRG---------IYQKLVIAKAGDNI--KVEIPVLGRPKPTVTWKKGDQ 21104
Query: 2141 MIFEEHGFRRTTPPTTATP--------IRHRPRPYPPN----VGEEIQIGHIPREDVDYH 2188
++ + +R TTAT +R PYP VGE + I D+
Sbjct: 21105 ILKQT---QRVNFETTATSTILNINECVRSDSGPYPLTARNIVGEVGDVITIQVHDIP-- 21159
Query: 2189 LYPHGPGLNPNASTGQEALSQTTISWAPFQDTSEYIISCHPV---GTDEEP-LQFRVPGT 2244
GP P + + T SW P ++ IS + V TD ++
Sbjct: 21160 ----GPPTGP-IKFDEVSSDFVTFSWDPPENDGGVPISNYVVEMRQTDSTTWVELATTVI 21214
Query: 2245 STSATLTGLTRGATYNIIVEALKDQQRHKVREEVVTVGNSVNEGLNQPTDDSCFDPYTVS 2304
T+ T LT G Y V+A Q R+ V + + N P V+
Sbjct: 21215 RTTYKATRLTTGLEYQFRVKA---QNRYGVGPGITSACIVANYPFKVPGPPGTPQVTAVT 21271
Query: 2305 HYAVGDEW-ERMSESGFKLL 2323
++ W E +S+ G +L
Sbjct: 21272 KDSMTISWHEPLSDGGSPIL 21291
Score = 128 bits (322), Expect = 6e-29
Identities = 343/1604 (21%), Positives = 574/1604 (35%), Gaps = 260/1604 (16%)
Query: 611 PVEVFITETPSQPNSHPIQWNAPQ---PSHISKYILRWRPKNSVGRWKEATIPGHLNS-- 665
P ++ I + S +S + W+ P S ++ Y++ R + W + G + +
Sbjct: 27170 PAKIRIAD--STKSSITLGWSKPVYDGGSAVTGYVVEIR-QGEEEEWTTVSTKGEVRTTE 27226
Query: 666 YTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATS 725
Y + LKPGV Y ++ ++ G E + + S +
Sbjct: 27227 YVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQAKDILEAPEIDLDVALRTSVIAKAG 27286
Query: 726 ESVTEITASSF----VVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLL 781
E V + V+W + G Y + E D L +P +
Sbjct: 27287 EDVQVLIPFKGRPPPTVTWRKDEKNL-GSDARYSI-ENTDSSSLLTIPQVTRNDT----- 27339
Query: 782 PGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ----AP 837
KYI+ + + + S + S P A V V ++ + W P +P
Sbjct: 27340 --GKYILTIENGVGEPKSSTV-SVKVLDTPAACQKLQVKHVSRGTVTLLWDPPLIDGGSP 27396
Query: 838 ITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQE 897
I Y I + + + + ++ ++ S L DL + + A E P E
Sbjct: 27397 IINYVIEKRDATKRTWSVVSHKCSSTSFKLIDLSEKTPFFFRVLAENEIGIGEPC----E 27452
Query: 898 TTGTPRSDTVPSP-RDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPVNLPGEHG- 951
TT ++ VP+P RDL + T V + WT P+ S +T Y V+ GE
Sbjct: 27453 TTEPVKAAEVPAPIRDLSMKDSTKTSVILSWTKPDFDGGSVITEY---VVERKGKGEQTW 27509
Query: 952 QRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDS 1011
IS+ EV+ L F+VFA + S P+T T + L E D
Sbjct: 27510 SHAGISKTCEIEVSQLKEQSVLEFRVFAKNEKGLSDPVTIGPITVKE----LIITPEVDL 27565
Query: 1012 TVLVRWTPPRAQIT---GYRLTVGLTRRGQPRQYNVGPSVS----KYPLRNLQ------P 1058
+ + P AQ+T G+ + + L +G+P+ PS+S PL+ +
Sbjct: 27566 SDI-----PGAQVTVRIGHNVHLELPYKGKPK-----PSISWLKDGLPLKESEFVRFSKT 27615
Query: 1059 ASEYTVSLVAIKGNQESPKATGVFT-------------TLQPGSSI--PPYNTEVTETTI 1103
++ T+S+ K + K T + TL P S P E+ ++
Sbjct: 27616 ENKITLSIKNAK-KEHGGKYTVILDNAVCRIAVPITVITLGPPSKPKGPIRFDEIKADSV 27674
Query: 1104 VITWTPAPRIGFKLGVRPSQGGEAP------REVTSDSGSIVVSG----------LTPGV 1147
+++W G GGE RE + + +V S L
Sbjct: 27675 ILSWDVPEDNG---------GGEITCYSIEKRETSQTNWKMVCSSVARTTFKVPNLVKDA 27725
Query: 1148 EYVYTIQVLRDGQERDAPIVNKVVTP-----LSPPTNLHLEANPDTGVLTVSWERSTTP- 1201
EY + ++ + P+V+ ++ + P + N + ++++W+
Sbjct: 27726 EYQFRVRA-ENRYGVSQPLVSSIIVAKHQFRIPGPPGKPVIYNVTSDGMSLTWDAPVYDG 27784
Query: 1202 --DITGYRITTTPTNG---QQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKES 1256
++TG+ + N Q+ N+ + + T L GL+Y VY S
Sbjct: 27785 GSEVTGFHVEKKERNSILWQKVNT--SPISGREYRAT--GLVEGLDYQFRVYAENSAGLS 27840
Query: 1257 VPISDT-----IIPEVPQLTDLSFVDITDSSIGLRWTPL---NSSTIIGYRITVVAAGEG 1308
P + + P P T ++D+T +I L+W P S I+GY I E
Sbjct: 27841 SPSDPSKFTLAVSPVDPPGTP-DYIDVTRETITLKWNPPLRDGGSKIVGYSIEKRQGNER 27899
Query: 1309 IPIFEDFVDSSVGYYTVTGLEPGIDYDISVI------TLINGGESAPTTLTQQTAVPPPT 1362
+ +F D S YTVTGL PG Y+ +I T+ +S+ +T+ VPP
Sbjct: 27900 W-VRCNFTDVSECQYTVTGLSPGDRYEFRIIARNAVGTISPPSQSSGIIMTRDENVPP-- 27956
Query: 1363 DLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNE---EDVAELSISPSDNAVVLTNL 1419
GP+ LV+ PV +D E+ + + +T++
Sbjct: 27957 ---IVEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMN---MEITDV 28010
Query: 1420 LPGTEYVV--------SVSSVYEQHESTPLRGRQKTGLDSPTG-----IDFSDITANSFT 1466
L T V V +V ++ S + K + G I F++IT T
Sbjct: 28011 LGSTSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQDTPGKVVGPIRFTNITGEKMT 28070
Query: 1467 VHWIAPR----ATITGYRI-RHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVA 1521
+ W AP A IT Y I + + ED+ S T L G EY + A
Sbjct: 28071 LWWDAPLNDGCAPITHYIIEKRETSRLAWALIEDKC--EAQSYTAIKLINGNEYQFRVSA 28128
Query: 1522 LN----GR--EESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGE 1575
+N GR + P++ Q TV D P E T S+ ++W P E
Sbjct: 28129 VNKFGVGRPLDSDPVVAQIQYTVPDAPGIPEPSNITGNSITLTWARP------------E 28176
Query: 1576 TGGNSPVQEFTV-----------------PGSKSTATISGLKPGVDYTITVYAVTGRGDS 1618
+ G S +Q++ + P S++ ++GL G +Y V A G
Sbjct: 28177 SDGGSEIQQYILERREKKSTRWVKVISKRPISETRFKVTGLTEGNEYEFHVMAENAAGVG 28236
Query: 1619 PASSKPISINYRTEIDKPSQ---MQVTDVQDNSISVKW----LPSSSPVTGYRVTTTPKN 1671
PAS I R ++ P ++VTD ++S++W + GY + +
Sbjct: 28237 PASGISRLIKCREPVNPPGPPTVVKVTDTSKTTVSLEWSKPVFDGGMEIIGYIIEMCKAD 28296
Query: 1672 GPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTA-VTNIDRPKGLA 1730
K +T T+ LQ EY V A N +G+ T + +DR L
Sbjct: 28297 LGDWHKVNAEACVKTRYTVTDLQAGEEYKFRVSAINGAGKGDSCEVTGTIKAVDR---LT 28353
Query: 1731 FTDVDVDS-IKIAWESPQGQVSRYRVTY----------SSPEDGIH---ELFPAPDGEED 1776
++D+D+ K G R + Y S P+ + ++
Sbjct: 28354 APELDIDANFKQTHVVRAGASIRLFIAYQGRPTPTAVWSKPDSNLSLRADIHTTDSFSTL 28413
Query: 1777 TAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPP 1836
T E +YT++V + T P P + F VT S + W P
Sbjct: 28414 TVENCNRNDAGKYTLTVENNSGSKSITFTVKVLDTPGP-PGPITFKDVTRGSATLMWDAP 28472
Query: 1837 NVQLTGYRVRVTPKEKTGPMKE----INLAPDSSSVVVSGLMVATKYEVSVYALKDTLTS 1892
+ G R+ EK + I+ V+ L Y V A+ +
Sbjct: 28473 LLD-GGARIHHYVVEKREASRRSWQVISEKCTRQIFKVNDLAEGVPYYFRVSAVNEYGVG 28531
Query: 1893 RPAQ--GVVTTLENVSPPRRARVTDATETTITISW----RTKTETITGFQVDAVPANGQT 1946
P + + E +PPRR V D ++++ ++W ITG+ ++
Sbjct: 28532 EPYEMPEPIVATEQPAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSDF 28591
Query: 1947 PIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATT 2006
++ + ++T+ L T+Y+ + ND S P +S I P
Sbjct: 28592 WVEAGHTKQL-TFTVERLVEKTEYEFRVKAKNDAGYSEPREAFSSVIIKEPQ------IE 28644
Query: 2007 PNSLLVSWQPPRARITGYIIKYEKPGSPPREVVP---RPRPGVT 2047
P + L IT +I K GSP VP RP P VT
Sbjct: 28645 PTADLTG-------ITNQLITC-KAGSPFTIDVPISGRPAPKVT 28680
Score = 124 bits (311), Expect = 1e-27
Identities = 291/1338 (21%), Positives = 513/1338 (38%), Gaps = 174/1338 (13%)
Query: 780 LLPGRKYI-----VNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRP 834
++ G +YI VN Y I E E +++ + P P P V ++ S+ V WSRP
Sbjct: 27030 IIKGNEYIFRVRAVNKYGIGEPLESDSVVAKNAFVTPGPPGIPEVTKITKNSMTVVWSRP 27089
Query: 835 QA----PITGYRIVYSPSVEGSSTEL---NLPETANSVTLSDLQPGVQYNI-TIYAVEEN 886
A I+GY + ++ + +T VT QY + + A +
Sbjct: 27090 IADGGSDISGYFLEKRDKKSLGWFKVLKETIRDTRQKVTGLTENSDYQYRVCAVNAAGQG 27149
Query: 887 QESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVI 942
S P + D P ++ + T +T+ W+ P SAVTGY V++
Sbjct: 27150 PFSEP---SEFYKAADPIDPPGPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVVEI- 27205
Query: 943 PVNLPGEHGQRLPIS-----RNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTK- 996
GE + +S R T V+ L PGV YYF+V AV+ + +P+ + +
Sbjct: 27206 ---RQGEEEEWTTVSTKGEVRTTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQA 27262
Query: 997 ---LDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQP--------RQYNVG 1045
L+AP E D V +R T A+ G + V + +G+P + N+G
Sbjct: 27263 KDILEAP-------EIDLDVALR-TSVIAK-AGEDVQVLIPFKGRPPPTVTWRKDEKNLG 27313
Query: 1046 PSVSKYPLRNLQPASEYTVS----------LVAIKGNQESPKATGVFTTL--QPGSSIPP 1093
S ++Y + N +S T+ ++ I+ PK++ V + P +
Sbjct: 27314 -SDARYSIENTDSSSLLTIPQVTRNDTGKYILTIENGVGEPKSSTVSVKVLDTPAACQKL 27372
Query: 1094 YNTEVTETTIVITWTP------APRIGFKLGVRPS---QGGEAPREVTSDSGSIV-VSGL 1143
V+ T+ + W P +P I + + R + + +S S ++ +S
Sbjct: 27373 QVKHVSRGTVTLLWDPPLIDGGSPIINYVIEKRDATKRTWSVVSHKCSSTSFKLIDLSEK 27432
Query: 1144 TPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDI 1203
TP V + G+ + K +P +L ++ + T V+ +SW T PD
Sbjct: 27433 TPFFFRVLAENEIGIGEPCETTEPVKAAEVPAPIRDLSMKDSTKTSVI-LSW---TKPDF 27488
Query: 1204 TGYRITTTPTNGQQGNSLEEVVHADQS-SCTFD----NLSPGLEYNVSVYTVKDDKESVP 1258
G + T ++G + HA S +C + LE+ V K + V
Sbjct: 27489 DGGSVITEYVVERKGKGEQTWSHAGISKTCEIEVSQLKEQSVLEFRVFAKNEKGLSDPVT 27548
Query: 1259 ISDTIIPEVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGY----RITVVAAGEGIPIFE- 1313
I + E+ ++ DI + + +R N + Y + ++ +G+P+ E
Sbjct: 27549 IGPITVKELIITPEVDLSDIPGAQVTVR-IGHNVHLELPYKGKPKPSISWLKDGLPLKES 27607
Query: 1314 DFVDSSVGYYTVT------GLEPGIDYDISVITLINGGESAPTTLTQQTAVPPPTDLRFT 1367
+FV S +T E G Y + + + T +T P +RF
Sbjct: 27608 EFVRFSKTENKITLSIKNAKKEHGGKYTVILDNAVCRIAVPITVITLGPPSKPKGPIRFD 27667
Query: 1368 NIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSI---SPSDNAVVLTNLLPGTE 1424
I D++ ++W P + + YS K E + S + + NL+ E
Sbjct: 27668 EIKADSVILSWDVPED-NGGGEITCYSIEKRETSQTNWKMVCSSVARTTFKVPNLVKDAE 27726
Query: 1425 YVVSVSSVYEQHESTPL-----RGRQKTGLDSPTGID-FSDITANSFTVHWIAP----RA 1474
Y V + S PL + + + P G ++T++ ++ W AP +
Sbjct: 27727 YQFRVRAENRYGVSQPLVSSIIVAKHQFRIPGPPGKPVIYNVTSDGMSLTWDAPVYDGGS 27786
Query: 1475 TITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQ 1534
+TG+ + + + + P S T L G +Y + A N S
Sbjct: 27787 EVTGFHVEKKERNSILWQKVNTSPISGREYRATGLVEGLDYQFRVYAENSAGLSSPSDPS 27846
Query: 1535 QSTVS----DVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYG---ETGGNSPVQEFTV 1587
+ T++ D P + + T ++ + W+ P + Y G V+
Sbjct: 27847 KFTLAVSPVDPPGTPDYIDVTRETITLKWNPPLRDGGSKIVGYSIEKRQGNERWVRCNFT 27906
Query: 1588 PGSKSTATISGLKPGVDYTITVYAVTGRGD-SPASSKPISINYRTEIDKPSQMQVTDVQD 1646
S+ T++GL PG Y + A G SP S I R E P + D
Sbjct: 27907 DVSECQYTVTGLSPGDRYEFRIIARNAVGTISPPSQSSGIIMTRDENVPPIVEFGPEYFD 27966
Query: 1647 -------NSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTK----TAGPDQTEMTIEGLQP 1695
S+ +K L PV RVT K+G K T T + +
Sbjct: 27967 GLIIKSGESLRIKALVQGRPVP--RVTWF-KDGVEIEKRMNMEITDVLGSTSLFVRDATR 28023
Query: 1696 TVEYVVSVYAQNPSGESQPLVQTAVTNIDRP----KGLAFTDVDVDSIKIAWESPQGQ-- 1749
V +V A+N SG ++ ++ V D P + FT++ + + + W++P
Sbjct: 28024 DHRGVYTVEAKNASGSAKAEIKVKVQ--DTPGKVVGPIRFTNITGEKMTLWWDAPLNDGC 28081
Query: 1750 --VSRYRVTYSSPEDGIHELFPAPDGEEDTAELQG-----LRPGSEYTVSVVALHD---- 1798
++ Y + L ED E Q L G+EY V A++
Sbjct: 28082 APITHYIIEKRETSRLAWALI------EDKCEAQSYTAIKLINGNEYQFRVSAVNKFGVG 28135
Query: 1799 -DMESQPLIGTQSTAIP-APTDLKFTQVTPTSLSAQWTPP----NVQLTGYRVRVTPKEK 1852
++S P++ +P AP + + +T S++ W P ++ Y + K+
Sbjct: 28136 RPLDSDPVVAQIQYTVPDAPGIPEPSNITGNSITLTWARPESDGGSEIQQYILERREKKS 28195
Query: 1853 TGPMKEINLAPDSSS-VVVSGLMVATKYEVSVYALKDTLTSRPAQGV---VTTLENVS-- 1906
T +K I+ P S + V+GL +YE V A ++ PA G+ + E V+
Sbjct: 28196 TRWVKVISKRPISETRFKVTGLTEGNEYEFHVMA-ENAAGVGPASGISRLIKCREPVNPP 28254
Query: 1907 -PPRRARVTDATETTITISWRTKT----ETITGFQVDAVPANGQTPIQRTIKPDVRS-YT 1960
PP +VTD ++TT+++ W I G+ ++ A+ + + V++ YT
Sbjct: 28255 GPPTVVKVTDTSKTTVSLEWSKPVFDGGMEIIGYIIEMCKADLGDWHKVNAEACVKTRYT 28314
Query: 1961 ITGLQPGTDYKIYLYTLN 1978
+T LQ G +YK + +N
Sbjct: 28315 VTDLQAGEEYKFRVSAIN 28332
Score = 124 bits (310), Expect = 2e-27
Identities = 338/1629 (20%), Positives = 573/1629 (35%), Gaps = 196/1629 (12%)
Query: 624 NSHPIQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNS--YTIKGLKPGVVYE 678
NS + W P+ S I +YIL R K S RW + ++ + + GL G YE
Sbjct: 28166 NSITLTWARPESDGGSEIQQYILERREKKST-RWVKVISKRPISETRFKVTGLTEGNEYE 28224
Query: 679 GQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVV 738
+++ G + PV P P V VT+ + ++ +
Sbjct: 28225 FHVMAENAAGVGPASGIS-RLIKCREPVNP--------PGPPTVV---KVTDTSKTTVSL 28272
Query: 739 SW----VSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQIS 794
W + G+ +E ++ GD + T + DL G +Y V I+
Sbjct: 28273 EWSKPVFDGGMEIIGYIIEMCKADLGDWHKVNAEACVKTRYTVTDLQAGEEYKFRVSAIN 28332
Query: 795 EDGEQSLILSTSQTTAPD--APPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGS 852
G+ T A D P+ +D + VVR Y+ +P+ S
Sbjct: 28333 GAGKGDSCEVTGTIKAVDRLTAPELDIDANFKQTHVVRAGASIRLFIAYQGRPTPTAVWS 28392
Query: 853 STELNLPETANSVTLSDLQPGVQYNIT-------IYAVEENQESTPVVIQQETTGTPRSD 905
+ NL A+ T N VE N S + + TP
Sbjct: 28393 KPDSNLSLRADIHTTDSFSTLTVENCNRNDAGKYTLTVENNSGSKSITFTVKVLDTPGP- 28451
Query: 906 TVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPGEHGQRLPISRNTF 961
P + F +VT T+MW P + + Y V+ + +R F
Sbjct: 28452 ----PGPITFKDVTRGSATLMWDAPLLDGGARIHHYVVEKREASRRSWQVISEKCTRQIF 28507
Query: 962 AEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQ----TTKLDAPTNLQFVNETDSTVLVRW 1017
+V L+ GV YYF+V AV+ +P + T + P L V+ + S+ ++ W
Sbjct: 28508 -KVNDLAEGVPYYFRVSAVNEYGVGEPYEMPEPIVATEQPAPPRRLDVVDTSKSSAVLAW 28566
Query: 1018 TPP----RAQITGYRLTVGLTRRGQPRQYNVGPSVS-KYPLRNLQPASEY---------- 1062
P ++ITGY L + ++G G + + + L +EY
Sbjct: 28567 LKPDHDGGSRITGYLLE--MRQKGSDFWVEAGHTKQLTFTVERLVEKTEYEFRVKAKNDA 28624
Query: 1063 -------TVSLVAIKGNQESPKA--TGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRI 1113
S V IK Q P A TG+ L + P+ +V I+ PAP++
Sbjct: 28625 GYSEPREAFSSVIIKEPQIEPTADLTGITNQLITCKAGSPFTIDVP-----ISGRPAPKV 28679
Query: 1114 GFKL-GVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVT 1172
+KL +R + T D ++ V G Y + + + + V+
Sbjct: 28680 TWKLEEMRLKETDRVSITTTKDRTTLTVKDSMRGDSGRYFLTLENTAGVKTFSVTVVVIG 28739
Query: 1173 PLSPPTNLHLEANPDTGVLTVSW---ERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQ 1229
P T ++ +SW + +IT Y + + + V Q
Sbjct: 28740 RPGPVTGPIEVSSVSAESCVLSWGEPKDGGGTEITNYIVEKRESGTTAWQLVNSSVKRTQ 28799
Query: 1230 SSCTFDNLSPGLEYNVSV-----YTVKDDKESVPI---SDTIIPEVPQLTDLSFVDITDS 1281
T +L+ +EY+ V + V ES PI + P P T ++ +
Sbjct: 28800 IKVT--HLTKYMEYSFRVSSENRFGVSKPLESAPIIAEHPFVPPSAP--TRPEVYHVSAN 28855
Query: 1282 SIGLRWTPL---NSSTIIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISV 1338
++ +RW S IIGY + + + E+ V Y VTGL G++Y
Sbjct: 28856 AMSIRWEEPYHDGGSKIIGYWVEKKERNTILWVKENKVPCLECNYKVTGLVEGLEYQFRT 28915
Query: 1339 ITLINGGES----APTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAPPP---SIDLTNFLV 1391
L G S A + Q V P T++ T+ + W+ P + +++
Sbjct: 28916 YALNAAGVSKASEASRPIMAQNPVDAPGRPEVTDVTRSTVSLIWSAPAYDGGSKVVGYII 28975
Query: 1392 RYSPVKNEEDVAELSIS---PSDNAVVLTNLLPGTEYVVSVSS------VYEQHEST-PL 1441
PV D L + SDN +T L G Y V + + + EST P+
Sbjct: 28976 ERKPVSEVGDGRWLKCNYTIVSDNFFTVTALSEGDTYEFRVLAKNAAGVISKGSESTGPV 29035
Query: 1442 RGRQ-----KTGLDSPTGIDFSDITANSFTVHWIA----PRATITGYRIRHHPEHFSGRP 1492
R K LD+ D I A S V A P I + +
Sbjct: 29036 TCRDEYAPPKAELDARLHGDLVTIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVS 29095
Query: 1493 REDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVP---RDLEVVA 1549
+ + I + + +Y +++ +G + +++ V D P L V
Sbjct: 29096 LQYTGKRATAVIKFCDRSDSGKYTLTVKNASGTKAVSVMV----KVLDSPGPCGKLTVSR 29151
Query: 1550 ATPTSLLISWDAP----AVTVRYYRITYGETGGNSPVQEFTVPGSKSTAT--ISGLKPGV 1603
T ++W P + +Y + ET S + V G T + ++ L
Sbjct: 29152 VTQEKCTLAWSLPQEDGGAEITHYIVERRET---SRLNWVIVEGECPTLSYVVTRLIKNN 29208
Query: 1604 DYTITVYAVTGRGDS-PASSKPI-SINYRTEIDKPSQMQVTDVQDNSISVKWLPSSS--- 1658
+Y V AV G P S+PI + N T P + I ++W S
Sbjct: 29209 EYIFRVRAVNKYGPGVPVESEPIVARNSFTIPSPPGIPEEVGTGKEHIIIQWTKPESDGG 29268
Query: 1659 -PVTGYRVTTTPKNGPGPTK-TKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLV 1716
++ Y V K T+ K T + + L +Y V A N +G S+P
Sbjct: 29269 NEISNYLVDKREKKSLRWTRVNKDYVVYDTRLKVTSLMEGCDYQFRVTAVNAAGNSEPSE 29328
Query: 1717 QTAVTNIDR-------PKGLAFTDVDVDSIKIAWESPQGQVSRYRVTY-----SSPEDGI 1764
+ + P D SI +AW P V Y D
Sbjct: 29329 ASNFISCREPSYTPGPPSAPRVVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDTDQW 29388
Query: 1765 HELFPAPDGEEDTAELQGLRPGSEYTVSVVALH---------DDMESQPLIGTQSTAIPA 1815
+ + + L+ G +Y+ V A++ E +P+ + +
Sbjct: 29389 YRVHTNATIRNTEFTVPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEIPDLEL 29448
Query: 1816 PTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTG---PMKEINLAPDSSSVVVSG 1872
DLK T S + V ++G V K G + I +S S+++
Sbjct: 29449 ADDLKKTVTIRAGASLRLM---VSVSGRPPPVITWSKQGIDLASRAIIDTTESYSLLI-- 29503
Query: 1873 LMVATKYEVSVYALKDTLTS--RPAQGVVTTLENVSPPRRARVTDATETTITISWRTKT- 1929
+ +Y+ Y ++ S + A +V + P +V + + ++TI+W T
Sbjct: 29504 VDKVNRYDAGKYTIEAENQSGKKSATVLVKVYDTPGPCPSVKVKEVSRDSVTITWEIPTI 29563
Query: 1930 ---ETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKI-----YLYTLNDNA 1981
+ + V+ A + T K Y I+GL GT Y +Y + +
Sbjct: 29564 DGGAPVNNYIVEKREAAMRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYGIGEPC 29623
Query: 1982 RSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPP----RARITGYIIKYEKPGSPPRE 2037
+S V+ + + P+ L + T +++ ++W+ P +R+TGY+++ K G+
Sbjct: 29624 ETSDAVLVSEVPL-VPAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGTERWM 29682
Query: 2038 VVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEP-----LIGRKKTDELP--QLVT 2090
V +P V E T+T L G +Y + A SEP + + LP L T
Sbjct: 29683 KVVTLKPTVLEHTVTSLNEGEQYLFRIRAQNEKGVSEPRETVTAVTVQDLRVLPTIDLST 29742
Query: 2091 LPHPNLHGP 2099
+P +H P
Sbjct: 29743 MPQKTIHVP 29751
Score = 123 bits (309), Expect = 2e-27
Identities = 310/1432 (21%), Positives = 508/1432 (35%), Gaps = 230/1432 (16%)
Query: 814 PPDPT-VDQVDDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTLS 868
PP P + V + W+ P +PI Y + + T ++ + +
Sbjct: 20475 PPGPVEISNVSAEKATLTWTPPLEDGGSPIKSYILEKRETSRLLWTVVSEDIQSCRHVAT 20534
Query: 869 DLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVE-VTDVKVTIMW 927
L G +Y + AV + PV Q E P P + V VT T+ W
Sbjct: 20535 KLIQGNEYIFRVSAVNHYGKGEPV--QSEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSW 20592
Query: 928 TPPE----SAVTGYRVDVIPV-NLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSH 982
P S +TGY V+ +L + P+S + +VTGL G TY F+V A +
Sbjct: 20593 KRPVDDGGSEITGYHVERREKKSLRWVRAIKTPVS-DLRCKVTGLQEGSTYEFRVSAENR 20651
Query: 983 GRESKPLTAQQTTKL-DA------PTNLQFVNETDSTVLVRWTPPR----AQITGYRLTV 1031
P A + + DA P+N + T + + W P +ITGY +
Sbjct: 20652 AGIGPPSEASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLAWGKPHYDGGLEITGYVVEH 20711
Query: 1032 GLTRRGQPRQYNVGPS--VSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGS 1089
+ G + ++++ + +LQ +Y + AI A +
Sbjct: 20712 QKVGDEAWIKDTTGTALRITQFVVPDLQTKEKYNFRISAINDAGVGEPAVIPDVEIVERE 20771
Query: 1090 SIPPY--NTEVTETTIVITWTPAPRIGFKLGVR-PSQGGEAPREVTSDSGSIVVSG---- 1142
P + + E+ T +V R G + + P +G AP EVT +I +
Sbjct: 20772 MAPDFELDAELRRTLVV-------RAGLSIRIFVPIKGRPAP-EVTWTKDNINLKNRANI 20823
Query: 1143 ---------LTPGVEYVYT---IQVLRDGQERDAPIVN-KVVTPLSPPTNLH-LEANPDT 1188
+ P T + + + + + VN +V+ P NL + D+
Sbjct: 20824 ENTESFTLLIIPECNRYDTGKFVMTIENPAGKKSGFVNVRVLDTPGPVLNLRPTDITKDS 20883
Query: 1189 GVLTVSWERSTTPD---ITGYRITTTPTNGQQGNSLEEVVHADQSSCTFD--NLSPGLEY 1243
+T+ W+ IT Y + + ++ H CT+ LS G EY
Sbjct: 20884 --VTLHWDLPLIDGGSRITNYIVEKREATRKSYSTATTKCH----KCTYKVTGLSEGCEY 20937
Query: 1244 NVSV-----YTVKDDKESV-PISDTIIPEVPQLTDLSFVDITDSSIGLRWTPLN---SST 1294
V Y + + E+ P+ + P P L+ +DIT S++ L W S
Sbjct: 20938 FFRVMAENEYGIGEPTETTEPVKASEAPSPPD--SLNIMDITKSTVSLAWPKPKHDGGSK 20995
Query: 1295 IIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLE-------PGIDYDISVITLINGGES 1347
I GY I G D TV GLE G +Y V+ + + G S
Sbjct: 20996 ITGYVIEAQRKGS---------DQWTHITTVKGLECVVRNLTEGEEYTFQVMAVNSAGRS 21046
Query: 1348 APT----TLTQQTAVPPPTDLR-------FTNIGPDT---MRVTWAPPPSIDLTNFLVRY 1393
AP + ++ + P DLR G + + V P P++
Sbjct: 21047 APRESRPVIVKEQTMLPELDLRGIYQKLVIAKAGDNIKVEIPVLGRPKPTVTW------- 21099
Query: 1394 SPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGL---- 1449
K + + + + + + +L E V S S Y PL R G
Sbjct: 21100 ---KKGDQILKQTQRVNFETTATSTILNINECVRSDSGPY------PLTARNIVGEVGDV 21150
Query: 1450 ---------DSPTG-IDFSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPRED 1495
PTG I F +++++ T W P I+ Y + S E
Sbjct: 21151 ITIQVHDIPGPPTGPIKFDEVSSDFVTFSWDPPENDGGVPISNYVVEMRQTD-STTWVEL 21209
Query: 1496 RVPHSRNSITLTNLTPGTEYVVSIVALN------GREESPLLIGQQSTVSDVPRDLEVVA 1549
R + T LT G EY + A N G + ++ V P +V A
Sbjct: 21210 ATTVIRTTYKATRLTTGLEYQFRVKAQNRYGVGPGITSACIVANYPFKVPGPPGTPQVTA 21269
Query: 1550 ATPTSLLISWDAP----AVTVRYYRITYGETGGN--SPVQEFTVPGSKSTATISGLKPGV 1603
T S+ ISW P + Y + E G V + VPG+ + SGL G+
Sbjct: 21270 VTKDSMTISWHEPLSDGGSPILGYHVERKERNGILWQTVSKALVPGNIFKS--SGLTDGI 21327
Query: 1604 DYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKW----LPSSSP 1659
Y V A G S S + ID P + ++ +++++KW
Sbjct: 21328 AYEFRVIAENMAGKSKPSKPSEPMLALDPIDPPGKPVPLNITRHTVTLKWAKPEYTGGFK 21387
Query: 1660 VTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQ-- 1717
+T Y V K + + E T+ GL Y V A+N +G P +
Sbjct: 21388 ITSYIVEKRDLPNGRWLKANFSNILENEFTVSGLTEDAAYEFRVIAKNAAGAISPPSEPS 21447
Query: 1718 TAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDT 1777
A+T D DV+ IK+ + + + + D P + +D
Sbjct: 21448 DAITCRD--------DVEAPKIKVDVKFKDTVILKAGEAFRLEADVSGRPPPTMEWSKDG 21499
Query: 1778 AELQGL---------------------RPGSEYTVSVVALHDDMESQPLIGTQSTAIPAP 1816
EL+G R YT++ A + ++ + + P P
Sbjct: 21500 KELEGTAKLEIKIADFSTNLVNKDSTRRDSGAYTLT--ATNPGGFAKHIFNVKVLDRPGP 21557
Query: 1817 TD--LKFTQVTPTSLSAQWTPP----NVQLTGYRVRVTPKEKTGPMKEINLAPD--SSSV 1868
+ L T+VT W PP ++ Y + K +T + N+A + + +
Sbjct: 21558 PEGPLAVTEVTSEKCVLSWFPPLDDGGAKIDHY---IVQKRETSRLAWTNVASEVQVTKL 21614
Query: 1869 VVSGLMVATKY-----EVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITI 1923
V+ L+ +Y V+ Y + + L S P V PP+ VT T+ ++ +
Sbjct: 21615 KVTKLLKGNEYIFRVMAVNKYGVGEPLESEPVL-AVNPYGPPDPPKNPEVTTITKDSMVV 21673
Query: 1924 SW----RTKTETITGFQVDAVPANGQTPIQRTIK--PDVRSYTITGLQPGTDYKIYLYTL 1977
W I + V+ GQ I+ K D+R Y ++GL G +Y+ +
Sbjct: 21674 CWGHPDSDGGSEIINYIVERRDKAGQRWIKCNKKTLTDLR-YKVSGLTEGHEYEFRIMAE 21732
Query: 1978 NDNARSSP-------VVIDASTAIDAPSNLRFLATTPNSLLVSWQPP----RARITGYII 2026
N S+P D P N R L T+ +S+ ++W P + ITGY++
Sbjct: 21733 NAAGISAPSPTSPFYKACDTVFKPGPPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMV 21792
Query: 2027 KYEKPGSPPREVVPRPRP-GVTEATITGLEPGTEYTIYVIALKNNQKSEPLI 2077
+ P ++V P T TITGL EY I + A+ + EP +
Sbjct: 21793 EIALPEEDEWQIVTPPAGLKATSYTITGLTENQEYKIRIYAMNSEGLGEPAL 21844
Score = 123 bits (309), Expect = 2e-27
Identities = 338/1634 (20%), Positives = 602/1634 (36%), Gaps = 228/1634 (13%)
Query: 613 EVFITETPSQPNSHP-----------IQWNAPQ---PSHISKYILRWRPKNSVGRWKEAT 658
E ++ P P P +QW P S I+ YI+ R GRW +A+
Sbjct: 23513 ECYVARDPCDPPGTPEPIMVKRNEITLQWTKPVYDGGSMITGYIVEKRDLPD-GRWMKAS 23571
Query: 659 IPGHLNS-YTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTP 717
+ + +T+ GL YE ++I+ G + S ST +T +
Sbjct: 23572 FTNVIETQFTVSGLTEDQRYEFRVIAKNAAGA-------ISKPSDST----GPITAKDEV 23620
Query: 718 FSPLVATSESVTEITASSFVVSWVSASD-------TVSGFRVEYELSEEGD-EPQYLDLP 769
P ++ + + ++ +D T+ R + E+ E E + D
Sbjct: 23621 ELPRISMDPKFRDTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFK 23680
Query: 770 STATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPT-VDQVDDTSIV 828
+ V + G +YI+ ++ G +S ++ P P P V V
Sbjct: 23681 ALLI-VKDAIRIDGGQYILRASNVA--GSKSFPVNVKVLDRPGPPEGPVQVTGVTSEKCS 23737
Query: 829 VRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITI---- 880
+ WS P + I+ Y + + + T + NS+ ++ L G +Y I
Sbjct: 23738 LTWSPPLQDGGSDISHYVVEKRETSRLAWTVVASEVVTNSLKVTKLLEGNEYVFRIMAVN 23797
Query: 881 -YAVEENQESTPVVIQQETTGTPRSDTVPSP-RDLQFVEVTDVKVTIMWTPPES----AV 934
Y V E ES PV+++ +P P + L+ + +T+ W P+S +
Sbjct: 23798 KYGVGEPLESAPVLMKNPFV-------LPGPPKSLEVTNIAKDSMTVCWNRPDSDGGSEI 23850
Query: 935 TGYRV---DVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTA 991
GY V D + + +R+ R VTGL+ Y F+V A + +P A
Sbjct: 23851 IGYIVEKRDRSGIRWIKCNKRRITDLR---LRVTGLTEDHEYEFRVSAENAAGVGEPSPA 23907
Query: 992 -------QQTTKLDAPTNLQFVNETDSTVLVRWTPP----RAQITGYRLTVGLTRRGQPR 1040
K PTN V+ T +++ + W P ++I GY V + + +
Sbjct: 23908 TVYYKACDPVFKPGPPTNAHIVDTTKNSITLAWGKPIYDGGSEILGY--VVEICKADEEE 23965
Query: 1041 QYNVGPS----VSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNT 1096
V P V+++ + L EY + + A+ +AT V T++P +
Sbjct: 23966 WQIVTPQTGLRVTRFEISKLTEHQEYKIRVCALN-KVGLGEATSVPGTVKPEDKLEAPEL 24024
Query: 1097 EVTETT---IVITWTPAPRIGFKLGVRPS-------QGGEAPREVTSDSG----SIVVSG 1142
++ IV+ + RI RP+ + GE +V + G + +
Sbjct: 24025 DLDSELRKGIVVRAGGSARIHIPFKGRPTPEITWSREEGEFTDKVQIEKGVNYTQLSIDN 24084
Query: 1143 LTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHL-EANPDTGVLTVSWERSTTP 1201
Y +++ + A + KV+ PP NL + E D+ L WE P
Sbjct: 24085 CDRNDAGKYILKLENSSGSKSAFVTVKVLDTPGPPQNLAVKEVRKDSAFLV--WE---PP 24139
Query: 1202 DITGYRITTTPTNGQQGNSLEEVVHAD----QSSCTFDNLSPGLEYNVSVYTVKDDKESV 1257
I G ++ ++ + + ++S +NL+ G Y V + V
Sbjct: 24140 IIDGGAKVKNYVIDKRESTRKAYANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFGVGV 24199
Query: 1258 PIS--DTIIPEVPQLTD--LSFVDITDSSIGLRWTPLN---SSTIIGYRITVVAAGEGIP 1310
P+ D + P ++ D++ +S L W S ++GY V +G
Sbjct: 24200 PVETVDAVKAAEPPSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLGY--VVEMQPKGTE 24257
Query: 1311 IFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTT---------LTQQTAVPPP 1361
+ +S V VTGL G +Y V G+S P LT Q ++ P
Sbjct: 24258 KWSIVAESKVCNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKLP 24317
Query: 1362 TDLRFTNIGPD---TMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTN 1418
+ G D + V P P+I +++ P+K +++ + + VL +
Sbjct: 24318 FNTYSIQAGEDLKIEIPVIGRPRPNI---SWVKDGEPLK---QTTRVNVEETATSTVL-H 24370
Query: 1419 LLPGTE------YVVSVSSVYEQHESTPLRGRQKTGLDSPTG-IDFSDITANSFTVHWIA 1471
+ G + V + +S E+ + +K G P G + F +++A+ + W
Sbjct: 24371 IKEGNKDDFGKYTVTATNSAGTATENLSVIVLEKPG--PPVGPVRFDEVSADFVVISWEP 24428
Query: 1472 PRAT----ITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREE 1527
P T I+ Y + + + +R +I +T L GTEY I A N +
Sbjct: 24429 PAYTGGCQISNYIVEKR-DTTTTTWHMVSATVARTTIKITKLKTGTEYQFRIFAENRYGK 24487
Query: 1528 SPLLIGQQSTVS------DVPRDLEVVAATPTSLLISWDAP----AVTVRYYRITYGETG 1577
S L + V P V + + +L+ W P + Y + E
Sbjct: 24488 SAPLDSKAVIVQYPFKEPGPPGTPFVTSISKDQMLVQWHEPVNDGGTKIIGYHLEQKEKN 24547
Query: 1578 GNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPS 1637
V+ P + +GL G++Y V A G S R D P
Sbjct: 24548 SILWVKLNKTPIQDTKFKTTGLDEGLEYEFKVSAENIVGIGKPSKVSECFVARDPCDPPG 24607
Query: 1638 QMQVTDVQDNSISVKW----LPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGL 1693
+ + + N++++KW S +TGY V K +TE T+ GL
Sbjct: 24608 RPEAIVITRNNVTLKWKKPAYDGGSKITGYIVEKKDLPDGRWMKASFTNVLETEFTVSGL 24667
Query: 1694 QPTVEYVVSVYAQNPSGE-SQPLVQT-AVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVS 1751
Y V A+N +G S+P + A+T D ++D + + + V
Sbjct: 24668 VEDQRYEFRVIARNAAGNFSEPSDSSGAITARD--------EIDAPNASLDPKYKDVIVV 24719
Query: 1752 RYRVTYSSPED----GIHELFPAPDGE--EDTAELQGLRPGSEYTVSVV--ALHDD---- 1799
T+ D I ++ + DG+ E+TA ++ + T VV + D
Sbjct: 24720 HAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQY 24779
Query: 1800 -MESQPLIGTQSTAI-------PAPTD--LKFTQVTPTSLSAQWTPPNVQLTGYRVR--V 1847
++ + GT+S I P P + LK T VT W PP +Q G + +
Sbjct: 24780 ILKLSNVGGTKSIPITVKVLDRPGPPEGPLKVTGVTAEKCYLAWNPP-LQDGGANISHYI 24838
Query: 1848 TPKEKTGPMK--EINLAPDSSSVVVSGLMVATKY-----EVSVYALKDTLTSRPAQGVVT 1900
K +T + +++ + + V+ L+ +Y V+ Y + + L S P
Sbjct: 24839 IEKRETSRLSWTQVSTEVQALNYKVTKLLPGNEYIFRVMAVNKYGIGEPLESGPVT-ACN 24897
Query: 1901 TLENVSPPRRARVTDATETTITISWRTKTE----TITGFQVDAVPANG--QTPIQRTIKP 1954
+ PP V+ T+ ++ ++W + I G+ ++ G T +
Sbjct: 24898 PYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDKEGVRWTKCNKKTLT 24957
Query: 1955 DVRSYTITGLQPGTDYKIYLYTLNDNARSSPV-------VIDASTAIDAPSNLRFLATTP 2007
D+R +TGL G Y+ + N P DA PSN + T+
Sbjct: 24958 DLR-LRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRACDALYPPGPPSNPKVTDTSR 25016
Query: 2008 NSLLVSWQPP----RARITGYIIKYEKPGSPPREVVPRPRPGV--TEATITGLEPGTEYT 2061
+S+ ++W P A + GY+++ K + P G+ + T+T L+ TEY
Sbjct: 25017 SSVSLAWSKPIYDGGAPVKGYVVEV-KEAAADEWTTCTPPTGLQGKQFTVTKLKENTEYN 25075
Query: 2062 IYVIALKNNQKSEP 2075
+ A+ + EP
Sbjct: 25076 FRICAINSEGVGEP 25089
Score = 123 bits (309), Expect = 2e-27
Identities = 314/1502 (20%), Positives = 546/1502 (36%), Gaps = 190/1502 (12%)
Query: 619 TPSQPNSHPIQWNAP---QPSHISKYILRWRPKNSVGRWKEATIPGHLNS--YTIKGLKP 673
T + +S + W+ P + + Y++ + + + W T P L +T+ LK
Sbjct: 25012 TDTSRSSVSLAWSKPIYDGGAPVKGYVVEVK-EAAADEWTTCTPPTGLQGKQFTVTKLKE 25070
Query: 674 GVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITA 733
Y ++ +I G E T + V + P L A V + A
Sbjct: 25071 NTEYNFRICAINSEGVGE------PATLPGSVVAQERIE---PPEIELDADLRKVVVLRA 25121
Query: 734 SSFVVSWVSASDTVSGFRVEYELSEEGDEP-----QYLDLPSTATSVNIPDLLPGRKYIV 788
S+ + +V T+ G R E E+ E E +++ S+ T + I ++
Sbjct: 25122 SATLRLFV----TIKG-RPEPEVKWEKAEGILTDRAQIEVTSSFTMLVIDNVTRFDSGRY 25176
Query: 789 NVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ----APITGYRIV 844
N+ + G ++ ++ +P AP + T+ +V S+ + W P A IT Y +
Sbjct: 25177 NLTLENNSGSKTAFVNVRVLDSPSAPVNLTIREVKKDSVTLSWEPPLIDGGAKITNYIVE 25236
Query: 845 YSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRS 904
+ + + T + + +LQ G Y + A E P ETT +
Sbjct: 25237 KRETTRKAYATITNNCTKTTFRIENLQEGCSYYFRVLASNEYGIGLPA----ETTEPVKV 25292
Query: 905 DTVPSPRD-LQFVEVTDVKVTIMWTPPES----AVTGYRVDVIPVNLPGEHGQRLPISRN 959
P P + V+VT TI W PES +TGY V++ E +
Sbjct: 25293 SEPPLPPGRVTLVDVTRNTATIKWEKPESDGGSKITGYVVEMQTKG--SEKWSTCTQVKT 25350
Query: 960 TFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWT- 1018
A ++GL+ G Y F+V AV+ S P +L P + + S L T
Sbjct: 25351 LEATISGLTAGEEYVFRVAAVNEKGRSDP------RQLGVPVIARDIEIKPSVELPFHTF 25404
Query: 1019 --PPRAQIT-------GYRLTVGLTRRGQP----RQYNVGPSVSKYPLRNLQPASEYTVS 1065
R Q+ + TV + GQ + NV S + L +++ AS+ V
Sbjct: 25405 NVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSL-SIKEASKEDVG 25463
Query: 1066 LVAIKGNQESPKATGVFTTL---QPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPS 1122
+ + + T T + +PG P EV+ +I I+W P G G + S
Sbjct: 25464 TYELCVSNSAGSITVPITIIVLDRPGPPGPIRIDEVSCDSITISWNPPEYDG---GCQIS 25520
Query: 1123 QGGEAPREVTSDSGSIV----------VSGLTPGVEYVYTIQVL-RDGQ----ERDAPIV 1167
+E TS + IV + LT G EY + + R G+ E A +
Sbjct: 25521 NYIVEKKETTSTTWHIVSQAVARTSIKIVRLTTGSEYQFRVCAENRYGKSSYSESSAVVA 25580
Query: 1168 NKVVTPLSPP-TNLHLEANPDTGVLTVSWERSTTPD---ITGYRITTTPTNGQQGNSLEE 1223
+P PP T + A T + V+W+ + GY + + + +
Sbjct: 25581 EYPFSPPGPPGTPKVVHATKST--MLVTWQVPVNDGGSRVIGYHLEYKERSSILWSKANK 25638
Query: 1224 VVHADQSSCTFDNLSPGLEYNVSVYT--------VKDDKESVPISDTIIPE-VPQLTDLS 1274
++ AD + L GL Y VY E VP D P P++T+
Sbjct: 25639 ILIAD-TQMKVSGLDEGLMYEYRVYAENIAGIGKCSKSCEPVPARDPCDPPGQPEVTN-- 25695
Query: 1275 FVDITDSSIGLRWTPLN---SSTIIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPG 1331
IT S+ L+W+ + + I GY + +G + ++ + Y+ VT L
Sbjct: 25696 ---ITRKSVSLKWSKPHYDGGAKITGYIVERRELPDGRWLKCNYTNIQETYFEVTELTED 25752
Query: 1332 IDYDISVI------TLINGGESAPTTLTQQTAVPPPT--DLRFTNI----GPDTMRVT-- 1377
Y+ V ++ ES + + PP D++F ++ + +++
Sbjct: 25753 QRYEFRVFARNAADSVSEPSESTGPIIVKDDVEPPRVMMDVKFRDVIVVKAGEVLKINAD 25812
Query: 1378 --WAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNL----LPGTEYVVSVSS 1431
P P I + E+ A I +DN +LT +YV+++ +
Sbjct: 25813 IAGRPLPVISWAKDGIEI------EERARTEIISTDNHTLLTVKDCIRRDTGQYVLTLKN 25866
Query: 1432 VYEQHE-STPLRGRQKTGLDSPTG-IDFSDITANSFTVHWIAPR----ATITGYRI-RHH 1484
V + + K G P G ++ + +TA ++ W P+ A I Y + +
Sbjct: 25867 VAGTRSVAVNCKVLDKPG--PPAGPLEINGLTAEKCSLSWGRPQEDGGADIDYYIVEKRE 25924
Query: 1485 PEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGR------EESPLLIGQQSTV 1538
H + E + S +T L G EY+ + +N E + TV
Sbjct: 25925 TSHLAWTICEGEL--QMTSCKVTKLLKGNEYIFRVTGVNKYGVGEPLESVAIKALDPFTV 25982
Query: 1539 SDVPRDLEVVAATPTSLLISWDAP----AVTVRYYRITYGETGGNSPVQEFTVPGSKSTA 1594
P LE+ + T S+ + W P + Y I E V+ P
Sbjct: 25983 PSPPTSLEITSVTKESMTLCWSRPESDGGSEISGYIIERREKNSLRWVRVNKKPVYDLRV 26042
Query: 1595 TISGLKPGVDYTITVYAVTGRGDS-PASSKPISINYRTEI---DKPSQMQVTDVQDNSIS 1650
+GL+ G +Y VYA G S P+ + P+ I + PS+ ++ D +I+
Sbjct: 26043 KSTGLREGCEYEYRVYAENAAGLSLPSETSPL-IRAEDPVFLPSPPSKPKIVDSGKTTIT 26101
Query: 1651 VKWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQ 1706
+ W+ +P+TGY V K+ KT TE TI GL EYV V +
Sbjct: 26102 IAWVKPLFDGGAPITGYTVEYK-KSDDTDWKTSIQSLRGTEYTISGLTTGAEYVFRVKSV 26160
Query: 1707 NPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRY---------RVTY 1757
N G S P + + D+D + K + V +
Sbjct: 26161 NKVGASDPSDSSDPQIAKEREEEPLFDIDSEMRKTLIVKAGASFTMTVPFRGRPVPNVLW 26220
Query: 1758 SSPEDGIHELFPAPDGEEDTA---ELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIP 1814
S P+ + + T+ E +YT+++ + ++ T P
Sbjct: 26221 SKPDTDLRTRAYVDTTDSRTSLTIENANRNDSGKYTLTIQNVLSAASLTLVVKVLDTPGP 26280
Query: 1815 APTDLKFTQVTPTSLSAQWTPP----NVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVV 1870
PT++ VT S W P + Y + K + N + S V
Sbjct: 26281 -PTNITVQDVTKESAVLSWDVPENDGGAPVKNYHIEKREASKKAWVSVTNNC-NRLSYKV 26338
Query: 1871 SGLMVATKYEVSVYALKDTLTSRPA---QGVVTTLENVSPPRRARVTDATETTITISW-- 1925
+ L Y V + PA +GV T E SPP + VT ++ +++++W
Sbjct: 26339 TNLQEGAIYYFRVSGENEFGVGIPAETKEGVKIT-EKPSPPEKLGVTSISKDSVSLTWLK 26397
Query: 1926 --RTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARS 1983
I + V+A+ + ++ + + ++GL+ ++Y ++ N S
Sbjct: 26398 PEHDGGSRIVHYVVEALEKGQKNWVKCAVAKSTH-HVVSGLRENSEYFFRVFAENQAGLS 26456
Query: 1984 SP 1985
P
Sbjct: 26457 DP 26458
Score = 120 bits (301), Expect = 2e-26
Identities = 286/1368 (20%), Positives = 511/1368 (37%), Gaps = 206/1368 (15%)
Query: 866 TLSDLQPGVQYNITIYAVEENQEST-PVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVT 924
T++ L G +Y + A EN+ T P + + D P + +V+ ++T
Sbjct: 18356 TVTRLIEGNEYIFRVRA--ENKIGTGPPTESKPVIAKTKYDKPGRPDPPEVTKVSKEEMT 18413
Query: 925 IMWTPPE----SAVTGYRVDVIPVNLPGEHGQR-LPISRNTFAE----VTGLSPGVTYYF 975
++W PPE ++TGY ++ +H R +P++++ E V L P Y F
Sbjct: 18414 VVWNPPEYDGGKSITGYFLEK-----KEKHSTRWVPVNKSAIPERRMKVQNLLPDHEYQF 18468
Query: 976 KVFAVSH------GRESKPLTAQQTTKLDAP-TNLQFVNETDSTVLVRWTPP----RAQI 1024
+V A + S+P+ A+ + P TN + V+ T ++ + W P A I
Sbjct: 18469 RVKAENEIGIGEPSLPSRPVVAKDPIEPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAPI 18528
Query: 1025 TGY------RLTVGLTRRGQPRQYNVGPSVSK-YPLRNLQPASEYTVSL-----VAIKGN 1072
GY ++ G R V K + + +L EY + V I
Sbjct: 18529 IGYVVEMRPKIADASPDEGWKRCNAAAQLVRKEFTVTSLDENQEYEFRVCAQNQVGIGRP 18588
Query: 1073 QESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWT-------------PAPRIGFKLGV 1119
E +A L+P P + + + +VI PAP++ ++
Sbjct: 18589 AELKEAIKPKEILEP----PEIDLDASMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVG 18644
Query: 1120 RPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTN 1179
+ + ++ +V+ T Y++ ++ E+ + +V+ P ++
Sbjct: 18645 IDNVVRKGQVDLVDTMAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFVNVRVLDTPGPVSD 18704
Query: 1180 LHLEANPDTGVLTVSW---ERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDN 1236
L + T VSW E +T Y + + + +++ V ++S N
Sbjct: 18705 LKVSDVTKTSC-HVSWAPPENDGGSQVTHYIVEKREADRKTWSTVTPEVK--KTSFHVTN 18761
Query: 1237 LSPGLEYNVSVYTVKDDKESVPI--------SDTII-PEVPQLTDLSFVDITDSSIGLRW 1287
L PG EY V V + VP SD + P+ P+ L ++T +S L W
Sbjct: 18762 LVPGNEYYFRVTAVNEYGPGVPTDVPKPVLASDPLSEPDPPR--KLEVTEMTKNSATLAW 18819
Query: 1288 TPL---NSSTIIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLING 1344
P + I GY + + + ++ VTGL+ G Y V
Sbjct: 18820 LPPLRDGGAKIDGYITSYREEEQPADRWTEYSVVKDLSLVVTGLKEGKKYKFRVAARNAV 18879
Query: 1345 GESAPTTL-----TQQTAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVK-- 1397
G S P ++ +PP + P+ + + I+ + + K
Sbjct: 18880 GVSLPREAEGVYEAKEQLLPPKI------LMPEQITIKAGKKLRIEAHVYGKPHPTCKWK 18933
Query: 1398 -NEEDV---AELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSP- 1452
E++V + L++ +D++ +L + S E T + + +D+P
Sbjct: 18934 KGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPG 18993
Query: 1453 ---TGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPH----SRNSIT 1505
D SDI A++ ++ W P G I ++ R D V ++ S
Sbjct: 18994 PPQPPFDISDIDADACSLSWHIPLED-GGSNITNYIVEKCDVSRGDWVTALASVTKTSCR 19052
Query: 1506 LTNLTPGTEYVVSIVALN--GREE---SPLLIGQ-QSTVSDVPRDLEVVAATPTSLLISW 1559
+ L PG EY+ + A N G E SP ++ Q V P++ V + ++W
Sbjct: 19053 VGKLIPGQEYIFRVRAENRFGISEPLTSPKMVAQFPFGVPSEPKNARVTKVNKDCIFVAW 19112
Query: 1560 DAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATI----------------SGLKPGV 1603
D P ++ G SP+ + + + + + +GL G+
Sbjct: 19113 DRP------------DSDGGSPIIGYLIERKERNSLLWVKANDTLVRSTEYPCAGLVEGL 19160
Query: 1604 DYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWL----PSSSP 1659
+Y+ +YA+ G SP S + R +D P + +V DV +++S+ W S
Sbjct: 19161 EYSFRIYALNKAGSSPPSKPTEYVTARMPVDPPGKPEVIDVTKSTVSLIWARPKHDGGSK 19220
Query: 1660 VTGYRVTTTPKNGPGPTKTKTAGPD--QTEMTIEGLQPTVEYVVSVYAQN------PSGE 1711
+ GY V G + TA Q E T GL+ +Y A+ PS
Sbjct: 19221 IIGYFVEACKLPGDKWVRCNTAPHQIPQEEYTATGLEEKAQYQFRAIARTAVNISPPSEP 19280
Query: 1712 SQP---LVQTAVTNIDRPKGL-------AFTDVDVDSIKIAWESPQGQVS-RYRVTYSSP 1760
S P L + ID + A T+V +D+ + P VS + T P
Sbjct: 19281 SDPVTILAENVPPRIDLSVAMKSLLTVKAGTNVCLDA--TVFGKPMPTVSWKKDGTLLKP 19338
Query: 1761 EDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPA-PTDL 1819
+GI A T EL + ++ A + I + P P +
Sbjct: 19339 AEGIK---MAMQRNLCTLELFSVNRKDSGDYTITAENSSGSKSATIKLKVLDKPGPPASV 19395
Query: 1820 KFTQVTPTSLSAQWTPP----NVQLTGYRVRVTPKEKTGP-MKEINLAPDSSSVVVSGLM 1874
K ++ W PP ++T Y V +E + P +++ +S V L+
Sbjct: 19396 KINKMYSDRAMLSWEPPLEDGGSEITNY--IVDKRETSRPNWAQVSATVPITSCSVEKLI 19453
Query: 1875 VATKYEVSV-----YALKDTLTSRPAQGVVTTLENVSPPRRAR---VTDATETTITISWR 1926
+Y+ + Y + D + + PA PP R +++ T+ +T+SW+
Sbjct: 19454 EGHEYQFRICAENKYGVGDPVFTEPA----IAKNPYDPPGRCDPPVISNITKDHMTVSWK 19509
Query: 1927 TKTE----TITGFQVDAVPANGQTPIQRTIKPDV-RSYTITGLQPGTDYKIYLYTLNDNA 1981
+ ITG+ ++ + KP + R+ TGLQ GT+Y+ + +N
Sbjct: 19510 PPADDGGSPITGYLLEKRETQAVNWTKVNRKPIIERTLKATGLQEGTEYEFRVTAINKAG 19569
Query: 1982 RSSPVVIDASTAIDA---------PSNLRFLATTPNSLLVSWQPPR----ARITGYIIKY 2028
P DAS A A P+ + TT +S+ +SW P + I GY+++
Sbjct: 19570 PGKP--SDASKAAYARDPQYPPGPPAFPKVYDTTRSSVSLSWGKPAYDGGSPIIGYLVEV 19627
Query: 2029 EKPGSPPREVVPRPRP-GVTEATITGLEPGTEYTIYVIALKNNQKSEP 2075
++ S P+ T +TGL T+Y V A+ S+P
Sbjct: 19628 KRADSDNWVRCNLPQNLQKTRFEVTGLMEDTQYQFRVYAVNKIGYSDP 19675
Score = 120 bits (301), Expect = 2e-26
Identities = 304/1512 (20%), Positives = 534/1512 (35%), Gaps = 204/1512 (13%)
Query: 718 FSPLVATSESVTEITASSFVVSW----VSASDTVSGFRVEYELSEEGDEPQYLDLPSTA- 772
F P T+ + + T +S ++W + G+ VE + + +E + P T
Sbjct: 23918 FKPGPPTNAHIVDTTKNSITLAWGKPIYDGGSEILGYVVE--ICKADEEEWQIVTPQTGL 23975
Query: 773 --TSVNIPDLLPGRKYIVNVYQISEDG--EQSLILSTSQTTAPDAPPDPTVDQVDDTSIV 828
T I L ++Y + V +++ G E + + T + P+ +D IV
Sbjct: 23976 RVTRFEISKLTEHQEYKIRVCALNKVGLGEATSVPGTVKPEDKLEAPELDLDSELRKGIV 24035
Query: 829 VRW---SRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYN-ITIYAVE 884
VR +R P G +P + S E + ++ GV Y ++I +
Sbjct: 24036 VRAGGSARIHIPFKGRP---TPEITWSREEGEFTDKVQ------IEKGVNYTQLSIDNCD 24086
Query: 885 ENQESTPVVIQQETTGTPRS-------DTVPSPRDLQFVEVTDVKVTIMWTPP----ESA 933
N ++ + ++G+ + DT P++L EV ++W PP +
Sbjct: 24087 RNDAGKYILKLENSSGSKSAFVTVKVLDTPGPPQNLAVKEVRKDSAFLVWEPPIIDGGAK 24146
Query: 934 VTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQ 993
V Y +D S+ +F +V L+ G YYF+V A + P+
Sbjct: 24147 VKNYVIDKRESTRKAYANVSSKCSKTSF-KVENLTEGAIYYFRVMAENEFGVGVPVETVD 24205
Query: 994 TTKLDAPTN------LQFVNETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYN 1043
K P + L V++T ++++ W P +++ GY V + +G +
Sbjct: 24206 AVKAAEPPSPPGKVTLTDVSQTSASLM--WEKPEHDGGSRVLGY--VVEMQPKGTEKWSI 24261
Query: 1044 VGPS-VSKYPLRNLQPASEYTVSLVAIKGNQES-PKATGVFT-----TLQPGSSIPPYNT 1096
V S V + L EY + A +S P+ GV T+QP +P +NT
Sbjct: 24262 VAESKVCNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKLP-FNT 24320
Query: 1097 ------EVTETTIVITWTPAPRIGF-KLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEY 1149
E + I + P P I + K G Q E T+ S + +
Sbjct: 24321 YSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFG 24380
Query: 1150 VYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTP---DITGY 1206
YT+ + V+ PP + +SWE I+ Y
Sbjct: 24381 KYTVTATNSAGTATENLSVIVLEKPGPPVGPVRFDEVSADFVVISWEPPAYTGGCQISNY 24440
Query: 1207 RITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTII-- 1264
+ T + + V +++ L G EY ++ +S P+ +
Sbjct: 24441 IVEKRDTTTTTWHMVSATVA--RTTIKITKLKTGTEYQFRIFAENRYGKSAPLDSKAVIV 24498
Query: 1265 ---------PEVPQLTDLSFVDITDSSIGLRW-TPLNS--STIIGYRITVVAAGEGIPIF 1312
P P +T +S + ++W P+N + IIGY + + +
Sbjct: 24499 QYPFKEPGPPGTPFVTSIS-----KDQMLVQWHEPVNDGGTKIIGYHLEQKEKNSILWVK 24553
Query: 1313 EDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQ----QTAVPPPTDLRFTN 1368
+ + TGL+ G++Y+ V G P+ +++ + PP
Sbjct: 24554 LNKTPIQDTKFKTTGLDEGLEYEFKVSAENIVGIGKPSKVSECFVARDPCDPPGRPEAIV 24613
Query: 1369 IGPDTMRVTWAPPP---SIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEY 1425
I + + + W P +T ++V K+ D + S TN+L TE+
Sbjct: 24614 ITRNNVTLKWKKPAYDGGSKITGYIVEK---KDLPDGRWMKAS-------FTNVLE-TEF 24662
Query: 1426 VVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITG-YR---I 1481
VS V +Q + R G S ITA AP A++ Y+ +
Sbjct: 24663 TVS-GLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARD---EIDAPNASLDPKYKDVIV 24718
Query: 1482 RHHPEHF------SGRPREDRV--------------PHSRNSITLTNL-------TPGTE 1514
H E F G+P D V +++I T L T G +
Sbjct: 24719 VHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQ 24778
Query: 1515 YVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAP----AVTVRYYR 1570
Y++ + + G + P+ + L+V T ++W+ P + +Y
Sbjct: 24779 YILKLSNVGGTKSIPITVKVLDRPGPPEGPLKVTGVTAEKCYLAWNPPLQDGGANISHYI 24838
Query: 1571 ITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRG-DSPASSKPISI-N 1628
I ET S Q T + + ++ L PG +Y V AV G P S P++ N
Sbjct: 24839 IEKRETSRLSWTQVSTEVQALNYK-VTKLLPGNEYIFRVMAVNKYGIGEPLESGPVTACN 24897
Query: 1629 YRTEIDKPSQMQVTDVQDNSISVKWL----PSSSPVTGYRVTTTPKNGPGPTKTKTAGPD 1684
PS +V+ + +S+ V W + + GY + K G TK
Sbjct: 24898 PYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDKEGVRWTKCNKKTLT 24957
Query: 1685 QTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQT-------AVTNIDRPKGLAFTDVDVD 1737
+ + GL Y V A+N +G +P + A+ P TD
Sbjct: 24958 DLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRACDALYPPGPPSNPKVTDTSRS 25017
Query: 1738 SIKIAWESP----QGQVSRYRVTYSSPEDGIHELFPAPDGEEDTA-ELQGLRPGSEYTVS 1792
S+ +AW P V Y V P G + + L+ +EY
Sbjct: 25018 SVSLAWSKPIYDGGAPVKGYVVEVKEAAADEWTTCTPPTGLQGKQFTVTKLKENTEYNFR 25077
Query: 1793 VVALHDDMESQPL-----IGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRV 1847
+ A++ + +P + Q P +L L A T R+ V
Sbjct: 25078 ICAINSEGVGEPATLPGSVVAQERIEPPEIELDADLRKVVVLRASAT--------LRLFV 25129
Query: 1848 TPKEKTGPM----KEINLAPDSSSVVVSGLMV------ATKYEVSVY--ALKDTLTSRPA 1895
T K + P K + D + + V+ T+++ Y L++ S+ A
Sbjct: 25130 TIKGRPEPEVKWEKAEGILTDRAQIEVTSSFTMLVIDNVTRFDSGRYNLTLENNSGSKTA 25189
Query: 1896 QGVVTTLENVSPPRRARVTDATETTITISWRTKT----ETITGFQVDAVPANGQTPIQRT 1951
V L++ S P + + + ++T+SW IT + V+ + T
Sbjct: 25190 FVNVRVLDSPSAPVNLTIREVKKDSVTLSWEPPLIDGGAKITNYIVEKRETTRKAYATIT 25249
Query: 1952 IKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAP----SNLRFLATTP 2007
++ I LQ G Y + N+ P + P + + T
Sbjct: 25250 NNCTKTTFRIENLQEGCSYYFRVLASNEYGIGLPAETTEPVKVSEPPLPPGRVTLVDVTR 25309
Query: 2008 NSLLVSWQPPRA----RITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIY 2063
N+ + W+ P + +ITGY+++ + GS + + EATI+GL G EY
Sbjct: 25310 NTATIKWEKPESDGGSKITGYVVEMQTKGSEKWSTCTQVK--TLEATISGLTAGEEYVFR 25367
Query: 2064 VIALKNNQKSEP 2075
V A+ +S+P
Sbjct: 25368 VAAVNEKGRSDP 25379
Score = 119 bits (298), Expect = 4e-26
Identities = 329/1550 (21%), Positives = 553/1550 (35%), Gaps = 222/1550 (14%)
Query: 601 PLQTYPSSSGPVEVFITETPSQPN-------SHPIQWNAPQ---PSHISKYILRWRPKNS 650
P +T P VF+ PS+P + I W P + I+ Y + ++ +
Sbjct: 26068 PSETSPLIRAEDPVFLPSPPSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEYKKSDD 26127
Query: 651 VGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNT 710
WK + YTI GL G Y ++ S+ + G + + +S P +
Sbjct: 26128 TD-WKTSIQSLRGTEYTISGLTTGAEYVFRVKSVNKVGASD-------PSDSSDPQIAKE 26179
Query: 711 VTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVS--GFRVEYELSEEGDEP----Q 764
E PL +E+ + V + S + TV G V L + D
Sbjct: 26180 REEE-----PLFDID---SEMRKTLIVKAGASFTMTVPFRGRPVPNVLWSKPDTDLRTRA 26231
Query: 765 YLDLPSTATSVNIPDLL--PGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQV 822
Y+D + TS+ I + KY + + + +L++ T P P + TV V
Sbjct: 26232 YVDTTDSRTSLTIENANRNDSGKYTLTIQNVLSAASLTLVVKVLDTPGP--PTNITVQDV 26289
Query: 823 DDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNI 878
S V+ W P+ AP+ Y I + + + + S +++LQ G Y
Sbjct: 26290 TKESAVLSWDVPENDGGAPVKNYHIEKREASKKAWVSVTNNCNRLSYKVTNLQEGAIYYF 26349
Query: 879 TIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAV 934
+ E P ++ G ++ P L ++ V++ W PE S +
Sbjct: 26350 RVSGENEFGVGIPAETKE---GVKITEKPSPPEKLGVTSISKDSVSLTWLKPEHDGGSRI 26406
Query: 935 TGYRVDVIPVNLPGEHGQR----LPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKP-- 988
Y V+ + E GQ+ ++++T V+GL Y+F+VFA + S P
Sbjct: 26407 VHYVVEAL------EKGQKNWVKCAVAKSTHHVVSGLRENSEYFFRVFAENQAGLSDPRE 26460
Query: 989 -LTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPS 1047
L + P + N TV VR G L V + G+P V S
Sbjct: 26461 LLLPVLIKEQLEPPEIDMKNFPSHTVYVR--------AGSNLKVDIPISGKPLP-KVTLS 26511
Query: 1048 VSKYPLR-NLQPASEYTV---------SLVAIKGNQESPKATGVFTTL---------QPG 1088
PL+ ++ +E T S+ A G E A TT +PG
Sbjct: 26512 RDGVPLKATMRFNTEITAENLTINLKESVTADAGRYEITAANSSGTTKAFINIVVLDRPG 26571
Query: 1089 SSI-PPYNTEVTETTIVITWTPAPRIG-------FKLGVRPSQGGEAPREVTSDSGSIVV 1140
P +++TE ++ + W P G L S T + V
Sbjct: 26572 PPTGPVVISDITEESVTLKWEPPKYDGGSQVTNYILLKRETSTAVWTEVSATVARTMMKV 26631
Query: 1141 SGLTPGVEYVYTIQV-----LRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSW 1195
LT G EY + I+ + D + V T PP+ + N +TV W
Sbjct: 26632 MKLTTGEEYQFRIKAENRFGISDHIDSACVTVKLPYTTPGPPSTPWV-TNVTRESITVGW 26690
Query: 1196 ERSTT---PDITGYRITTTPTNG---QQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYT 1249
+ + GY + N Q+ N L V+ T +S GL Y VY
Sbjct: 26691 HEPVSNGGSAVVGYHLEMKDRNSILWQKANKL--VIRTTHFKVT--TISAGLIYEFRVYA 26746
Query: 1250 V------KDDKESVPISDTIIPEVPQLTDLSFVDITDSSIGLRWTPL---NSSTIIGYRI 1300
K S P+ E P+ ++ DI+ +S+ L W S I GY +
Sbjct: 26747 ENAAGVGKPSHPSEPVLAIDACEPPR--NVRITDISKNSVSLSWQQPAFDGGSKITGYIV 26804
Query: 1301 TVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISV------------------ITLI 1342
+G F + + + ++GL Y+ V IT I
Sbjct: 26805 ERRDLPDGRWTKASFTNVTETQFIISGLTQNSQYEFRVFARNAVGSISNPSEVVGPITCI 26864
Query: 1343 N--GGE--SAPTTLTQQTAVPPPTD--LRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPV 1396
+ GG P T+ T LR G + W TN LV V
Sbjct: 26865 DSYGGPVIDLPLEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALV---CV 26921
Query: 1397 KNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTG-I 1455
+N D+A + I +D L Y + + + +T +R + P G I
Sbjct: 26922 ENTTDLASILIKDADR-------LNSGCYELKLRNAMGSASAT-IRVQILDKPGPPGGPI 26973
Query: 1456 DFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNS-------ITLTN 1508
+F +TA T+ W P A G +I H + + RV S S IT T
Sbjct: 26974 EFKTVTAEKITLLW-RPPADDGGAKITH---YIVEKRETSRVVWSMVSEHLEECIITTTK 27029
Query: 1509 LTPGTEYVVSIVALNGRE-----ESPLLIGQQSTVSDVPRDL-EVVAATPTSLLISWDAP 1562
+ G EY+ + A+N ES ++ + + V+ P + EV T S+ + W P
Sbjct: 27030 IIKGNEYIFRVRAVNKYGIGEPLESDSVVAKNAFVTPGPPGIPEVTKITKNSMTVVWSRP 27089
Query: 1563 A------VTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRG 1616
++ + ++ G V + T+ ++ T GL DY V AV G
Sbjct: 27090 IADGGSDISGYFLEKRDKKSLGWFKVLKETIRDTRQKVT--GLTENSDYQYRVCAVNAAG 27147
Query: 1617 DSPASSKPISINYRTEID---KPSQMQVTDVQDNSISVKW----LPSSSPVTGYRVTTTP 1669
P S ID P+++++ D +SI++ W S VTGY V
Sbjct: 27148 QGPFSEPSEFYKAADPIDPPGPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVVEIRQ 27207
Query: 1670 KNGPGPTKTKTAGPDQ-TEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKG 1728
T T G + TE + L+P V Y V A N +G+ +P+ +
Sbjct: 27208 GEEEEWTTVSTKGEVRTTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMN--EPVQAKDI 27265
Query: 1729 LAFTDVDVD-SIKIAWESPQGQVSRYRVTYSS--PEDGIHELFPAPDGEEDTAELQGLRP 1785
L ++D+D +++ + + G+ + + + P G + ++
Sbjct: 27266 LEAPEIDLDVALRTSVIAKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYSIENTDS 27325
Query: 1786 GSEYTVSVVALHDDME---------SQPLIGTQSTAI----PAPTDLKFTQVTPTSLSAQ 1832
S T+ V +D + +P T S + A L+ V+ +++
Sbjct: 27326 SSLLTIPQVTRNDTGKYILTIENGVGEPKSSTVSVKVLDTPAACQKLQVKHVSRGTVTLL 27385
Query: 1833 WTPPNVQLTGYRVRVTPKEKTGPMKEINLAP---DSSSVVVSGLMVATKYEVSVYALKDT 1889
W PP + + +++ + ++ S+S + L T + V A +
Sbjct: 27386 WDPPLIDGGSPIINYVIEKRDATKRTWSVVSHKCSSTSFKLIDLSEKTPFFFRVLAENEI 27445
Query: 1890 LTSRPAQGV--VTTLENVSPPRRARVTDATETTITISWRTKTE-----TITGFQVDAVPA 1942
P + V E +P R + D+T+T++ +SW TK + IT + V+
Sbjct: 27446 GIGEPCETTEPVKAAEVPAPIRDLSMKDSTKTSVILSW-TKPDFDGGSVITEYVVERKGK 27504
Query: 1943 NGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDAST 1992
QT I ++ L+ + + ++ N+ S PV I T
Sbjct: 27505 GEQTWSHAGISKTC-EIEVSQLKEQSVLEFRVFAKNEKGLSDPVTIGPIT 27553
Score = 118 bits (296), Expect = 6e-26
Identities = 330/1625 (20%), Positives = 588/1625 (36%), Gaps = 230/1625 (14%)
Query: 611 PVEVFITETPSQPNSHPIQWNAP---QPSHISKYILRWRPKNSVGRWKEATIPGHLNSYT 667
PV V + E +S + W P S I Y+++ R W T S+
Sbjct: 19790 PVNVTVKEISK--DSAYVTWEPPIIDGGSPIINYVVQKRDAERKS-WSTVTTECSKTSFR 19846
Query: 668 IKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSES 727
+ L+ G Y ++ + +YG + T + V TP P+V
Sbjct: 19847 VANLEEGKSYFFRVFAENEYGIGDPGE------------TRDAVKASQTP-GPVVDLK-- 19891
Query: 728 VTEITASSFVVSWVS----ASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPG 783
V ++ SS + W + G+ V++ L+EE + + S + + DL G
Sbjct: 19892 VRSVSKSSCSIGWKKPHSDGGSRIIGYVVDF-LTEENKWQRVMK--SLSLQYSAKDLTEG 19948
Query: 784 RKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWS---RPQAPITG 840
++Y V +E+GE + T PD + + D + + + R + PI G
Sbjct: 19949 KEYTFRVSAENENGEGTPSEITVVARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPIKG 20008
Query: 841 YRIVYSPSVE--------GSSTELNLPETANSVTLS--DLQPGV--QYNITIYAVEENQE 888
+PSV + T +++ +A + TL D Q +Y IT+ V +E
Sbjct: 20009 KP---APSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKE 20065
Query: 889 STPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPV 944
T I + G P T P ++F EVT +T+ W PP+ S +T Y ++
Sbjct: 20066 GT---ISIKVVGKPGIPTGP----IKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRD- 20117
Query: 945 NLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKV-----FAVSHGRESKPLTAQQTTKL-D 998
++ + + T VT L G+ Y F+V + V G +S+P+ A+ + D
Sbjct: 20118 SVNNKWVTCASAVQKTTFRVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVPD 20177
Query: 999 APTNLQFVNETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGP-SVSKYPL 1053
AP V+ +V + WT P+ + ITGY L ++ N P + + +
Sbjct: 20178 APPPPNIVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTPIRMRDFKV 20237
Query: 1054 RNLQPASEYTVSLVAI------KGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITW 1107
L EY ++AI K + S + PG P +T ++ + W
Sbjct: 20238 TGLTEGLEYEFRVMAINLAGVGKPSLPSEPVVALDPIDPPGK---PEVINITRNSVTLIW 20294
Query: 1108 T-PAPRIGFKL-------GVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDG 1159
T P G KL PS+ V + V+ L G +Y + I+
Sbjct: 20295 TEPKYDGGHKLTGYIVEKRDLPSKSWMKANHVNVPECAFTVTDLVEGGKYEFRIRAKNTA 20354
Query: 1160 QERDAPIVN----------KVVTPLSPPT---NLHLEANPDTGVLTV-----------SW 1195
AP + + T + PT L ++A DT VL SW
Sbjct: 20355 GAISAPSESTETIICKDEYEAPTIVLDPTIKDGLTIKAG-DTIVLNAISILGKPLPKSSW 20413
Query: 1196 ERS----TTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVK 1251
++ DIT +IT+TPT+ +++ D T +P + K
Sbjct: 20414 SKAGKDIRPSDIT--QITSTPTSSML--TIKYATRKDAGEYTITATNP--------FGTK 20461
Query: 1252 DDKESVPISDTIIPEVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGEGIPI 1311
+ V + D +P P ++S +++ L WTP + ++ E +
Sbjct: 20462 VEHVKVTVLD--VPGPPGPVEIS--NVSAEKATLTWTPPLEDGGSPIKSYILEKRETSRL 20517
Query: 1312 FEDFVDSSVG--YYTVTGLEPGIDYDISVITLINGG-----ESAPTTLTQQTAVP-PPTD 1363
V + + T L G +Y V + + G +S P + + P PP
Sbjct: 20518 LWTVVSEDIQSCRHVATKLIQGNEYIFRVSAVNHYGKGEPVQSEPVKMVDRFGPPGPPEK 20577
Query: 1364 LRFTNIGPDTMRVTWAPP---PSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLL 1420
+N+ +T V+W P ++T + V K+ V + SD +T L
Sbjct: 20578 PEVSNVTKNTATVSWKRPVDDGGSEITGYHVERREKKSLRWVRAIKTPVSDLRCKVTGLQ 20637
Query: 1421 PGTEYVVSVSSVYEQHESTPLRGRQKTGLDS-------PTGIDFSDITANSFTVHWIAPR 1473
G+ Y VS+ P + P+ +D T S ++ W P
Sbjct: 20638 EGSTYEFRVSAENRAGIGPPSEASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLAWGKPH 20697
Query: 1474 ----ATITGYRIRHHPEHFSGRPREDRVPHSR-NSITLTNLTPGTEYVVSIVALN--GRE 1526
ITGY + H ++ R + +L +Y I A+N G
Sbjct: 20698 YDGGLEITGYVVEHQKVGDEAWIKDTTGTALRITQFVVPDLQTKEKYNFRISAINDAGVG 20757
Query: 1527 ESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFT 1586
E ++ + ++ D E+ A +L++ +++R + G P E T
Sbjct: 20758 EPAVIPDVEIVEREMAPDFELDAELRRTLVV---RAGLSIRIFVPIKGR-----PAPEVT 20809
Query: 1587 -VPGSKSTATISGLKPGVDYTITVYAVTGRGD---------SPASSKPISINYRTEIDKP 1636
+ + + ++ +T+ + R D +PA K +N R +D P
Sbjct: 20810 WTKDNINLKNRANIENTESFTLLIIPECNRYDTGKFVMTIENPAGKKSGFVNVRV-LDTP 20868
Query: 1637 S---QMQVTDVQDNSISVKW----LPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMT 1689
++ TD+ +S+++ W + S +T Y V T T +
Sbjct: 20869 GPVLNLRPTDITKDSVTLHWDLPLIDGGSRITNYIVEKREATRKS-YSTATTKCHKCTYK 20927
Query: 1690 IEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDR----PKGLAFTDVDVDSIKIAWES 1745
+ GL EY V A+N G +P T P L D+ ++ +AW
Sbjct: 20928 VTGLSEGCEYFFRVMAENEYGIGEPTETTEPVKASEAPSPPDSLNIMDITKSTVSLAWPK 20987
Query: 1746 PQ----GQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHD--- 1798
P+ +++ Y + G E ++ L G EYT V+A++
Sbjct: 20988 PKHDGGSKITGYVIEAQRKGSDQWTHITTVKGLE--CVVRNLTEGEEYTFQVMAVNSAGR 21045
Query: 1799 --DMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPM 1856
ES+P+I + T +P Q + + + + G R + T K G
Sbjct: 21046 SAPRESRPVIVKEQTMLPELDLRGIYQKLVIAKAGDNIKVEIPVLG-RPKPTVTWKKGDQ 21104
Query: 1857 -----KEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVS----- 1906
+ +N ++S +++ + + + Y LT+R G V + +
Sbjct: 21105 ILKQTQRVNFETTATSTILN-INECVRSDSGPY----PLTARNIVGEVGDVITIQVHDIP 21159
Query: 1907 --PPRRARVTDATETTITISWRTKTE----TITGFQVDAVPANGQTPIQRTIKPDVRSYT 1960
P + + + +T SW I+ + V+ + T ++ +Y
Sbjct: 21160 GPPTGPIKFDEVSSDFVTFSWDPPENDGGVPISNYVVEMRQTDSTTWVELATTVIRTTYK 21219
Query: 1961 ITGLQPGTDYKIYL-----YTLNDNARSSPVVIDASTAIDAPSNL-RFLATTPNSLLVSW 2014
T L G +Y+ + Y + S+ +V + + P + A T +S+ +SW
Sbjct: 21220 ATRLTTGLEYQFRVKAQNRYGVGPGITSACIVANYPFKVPGPPGTPQVTAVTKDSMTISW 21279
Query: 2015 QPP----RARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNN 2070
P + I GY ++ ++ + V + +GL G Y VIA
Sbjct: 21280 HEPLSDGGSPILGYHVERKERNGILWQTVSKALVPGNIFKSSGLTDGIAYEFRVIAENMA 21339
Query: 2071 QKSEP 2075
KS+P
Sbjct: 21340 GKSKP 21344
Score = 116 bits (291), Expect = 2e-25
Identities = 288/1381 (20%), Positives = 498/1381 (36%), Gaps = 191/1381 (13%)
Query: 766 LDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDT 825
+D + TS I + G K + ++ G+ ++ P + V + D
Sbjct: 13045 IDTTAEQTSFRILEAKKGDKGRYKIVLQNKHGKAEGFINLKVIDVPGPVRNLEVTETFDG 13104
Query: 826 SIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETAN-SVTLSDLQPG-VQYNIT 879
+ + W P + I GY +V ++ + L + T++ LQ G V+Y
Sbjct: 13105 EVSLAWEEPLTDGGSKIIGY-VVERRDIKRKTWVLATDRAESCEFTVTGLQKGGVEYLFR 13163
Query: 880 IYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVT 935
+ A PV + D P ++ +V V++ W PPE + +T
Sbjct: 13164 VSARNRVGTGEPVETDNPVEARSKYDVPGPPLNVTITDVNRFGVSLTWEPPEYDGGAEIT 13223
Query: 936 GYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTT 995
Y +++ + + A VT + G Y F+V A + KP A
Sbjct: 13224 NYVIELRDKTSIRWDTAMTVRAEDLSATVTDVVEGQEYSFRVRAQNRIGVGKPSAATPFV 13283
Query: 996 KL-------DAPTNLQFVNETDSTVLVRWTPP----RAQITGYRLTVGLTRRGQPR---- 1040
K+ P NL ++T S+V ++W PP + I GY + G+
Sbjct: 13284 KVADPIERPSPPVNLTSSDQTQSSVQLKWEPPLKDGGSPILGY--IIERCEEGKDNWIRC 13341
Query: 1041 QYNVGPSVSKYPLRNLQPASE--YTVSLVAIKGNQESPKATGVFTT----LQPGSSIPPY 1094
+ P ++ Y + L+ ++ Y VS G + + G T ++P + +
Sbjct: 13342 NMKLVPELT-YKVTGLEKGNKYLYRVSAENKAGVSDPSEILGPLTADDAFVEPTMDLSAF 13400
Query: 1095 NTEV-----TETTIVI--TWTPAPRIGFKLGVRPSQGGEAPREVT-SDSGSIVVSGLTPG 1146
+ TI++ T P P + G + + G+ + T S +V+S
Sbjct: 13401 KDGLEVIVPNPITILVPSTGYPRPTATWCFGDKVLETGDRVKMKTLSAYAELVISPSERS 13460
Query: 1147 VEYVYTIQVLRDGQERDAPI-VNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPD--- 1202
+ +YT+++ + I VN + P +P + D+ LT WE PD
Sbjct: 13461 DKGIYTLKLENRVKTISGEIDVNVIARPSAPKELKFGDITKDSVHLT--WE---PPDDDG 13515
Query: 1203 ---ITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSV------------ 1247
+TGY + + + + + V T +L G EY V
Sbjct: 13516 GSPLTGYVVEKREVSRKTWTKVMDFV--TDLEFTVPDLVQGKEYLFKVCARNKCGPGEPA 13573
Query: 1248 YTVKDDKESVPISDTIIPEVPQLTDLSFVDITDSSIGLRWTPLNS---STIIGYRITVVA 1304
Y + S P + +P+ P+ ++ + D T +SI L W P + S I GY +
Sbjct: 13574 YVDEPVNMSTPAT---VPDPPE--NVKWRDRTANSIFLTWDPPKNDGGSRIKGYIVERCP 13628
Query: 1305 AGE------GIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQ--- 1355
G G P+ E ++ VTGLE G Y V L G S P+ T++
Sbjct: 13629 RGSDKWVACGEPVAETKME-------VTGLEEGKWYAYRVKALNRQGASKPSRPTEEIQA 13681
Query: 1356 --TAVPPPTDLRFTNIGPDTMR----------VTWAPPPSIDLTNFLVRYSPVKNEEDVA 1403
T P L + T++ VT P P I T + + ++
Sbjct: 13682 VDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWT----KADMILKQDKRI 13737
Query: 1404 ELSISPSDNAVVLTNLL---PGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDI 1460
+ P + V + + GT + +V+ + K G P D +D+
Sbjct: 13738 TIENVPKKSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNVLDKPG--PPAAFDITDV 13795
Query: 1461 TANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRNS------ITLTNLT 1510
T S + W PR + IT Y + R + V H +S T L
Sbjct: 13796 TNESCLLTWNPPRDDGGSKITNYVVER-------RATDSEVWHKLSSTVKDTNFKATKLI 13848
Query: 1511 PGTEYVVSIVALN------GREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAP-- 1562
P EY+ + A N + SP+ Q P LE T ++ ++W P
Sbjct: 13849 PNKEYIFRVAAENMYGVGEPVQASPITAKYQFDPPGPPTRLEPSDITKDAVTLTWCEPDD 13908
Query: 1563 --AVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYA--VTGRGDS 1618
+ Y + + + V+ +P +T + GL Y V A + G G
Sbjct: 13909 DGGSPITGYWVERLDPDTDKWVRCNKMPVKDTTYRVKGLTNKKKYRFRVLAENLAGPGKP 13968
Query: 1619 PASSKPISINYRTEID---KPSQMQVTDVQDNSISVKWL----PSSSPVTGYRVTTTPKN 1671
S++PI I + ID P + V DV S+ + W + + Y V K
Sbjct: 13969 SKSTEPILI--KDPIDPPWPPGKPTVKDVGKTSVRLNWTKPEHDGGAKIESY-VIEMLKT 14025
Query: 1672 GPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQP-------LVQTAVTNID 1724
G G T+ + GL EY V A N +GES+P L + +
Sbjct: 14026 GTDEWVRVAEGVPTTQHLLPGLMEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPS 14085
Query: 1725 RPKGLAFTDVDVDSIKIAWESPQ----GQVSRYRVTYSSPEDGIHELFPAPDG--EEDTA 1778
P+ L ++ ++ + W P+ ++ Y V D + + D ++
Sbjct: 14086 PPRWLEVINITKNTADLKWTVPEKDGGSPITNYIV---EKRDVRRKGWQTVDTTVKDTKC 14142
Query: 1779 ELQGLRPGSEYTVSVVAL-------HDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSA 1831
+ L GS Y V A + ++E L T P L VT +
Sbjct: 14143 TVTPLTEGSLYVFRVAAENAIGQSDYTEIEDSVLAKDTFTTPGPPYALAVVDVTKRHVDL 14202
Query: 1832 QWTPPNVQ--LTGYRVRVTPKEKTGP--MKEINLAPDSSSVVVSGLMVATKYEVSVYALK 1887
+W PP R + KE+ G +K A + V+ ++ T+ + V A
Sbjct: 14203 KWEPPKNDGGRPIQRYVIEKKERLGTRWVKAGKTAGPDCNFRVTDVIEGTEVQFQVRAEN 14262
Query: 1888 DTLTSRPAQGV-VTTLEN----VSPPRRARVTDATETTITISWRTKTET----ITGFQVD 1938
+ P++ + ++E+ SPP VTDA I I+W+ + I G+ V+
Sbjct: 14263 EAGVGHPSEPTEILSIEDPTSPPSPPLDLHVTDAGRKHIAIAWKPPEKNGGSPIIGYHVE 14322
Query: 1939 AVPANGQTPIQRTIKP--DVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDA 1996
P + ++ +P D++ G+ P +Y + + +N S P I +
Sbjct: 14323 MCPVGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAIGVSEPSEISENVVAKD 14382
Query: 1997 P 1997
P
Sbjct: 14383 P 14383
Score = 115 bits (287), Expect = 7e-25
Identities = 286/1430 (20%), Positives = 524/1430 (36%), Gaps = 172/1430 (12%)
Query: 785 KYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPT-VDQVDDTSIVVRWSRPQ----APIT 839
+Y++ + ++ G +S+ ++ P P P ++ + + W RPQ A I
Sbjct: 25859 QYVLTLKNVA--GTRSVAVNCKVLDKPGPPAGPLEINGLTAEKCSLSWGRPQEDGGADID 25916
Query: 840 GYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETT 899
Y + + + T S ++ L G +Y + V + P+ E+
Sbjct: 25917 YYIVEKRETSHLAWTICEGELQMTSCKVTKLLKGNEYIFRVTGVNKYGVGEPL----ESV 25972
Query: 900 GTPRSD--TVPSP-RDLQFVEVTDVKVTIMWTPPES----AVTGYRVDVIPVN-LPGEHG 951
D TVPSP L+ VT +T+ W+ PES ++GY ++ N L
Sbjct: 25973 AIKALDPFTVPSPPTSLEITSVTKESMTLCWSRPESDGGSEISGYIIERREKNSLRWVRV 26032
Query: 952 QRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNL-------Q 1004
+ P+ + + TGL G Y ++V+A + S P + + P L +
Sbjct: 26033 NKKPVY-DLRVKSTGLREGCEYEYRVYAENAAGLSLPSETSPLIRAEDPVFLPSPPSKPK 26091
Query: 1005 FVNETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPAS 1060
V+ +T+ + W P A ITGY + + + ++Y + L +
Sbjct: 26092 IVDSGKTTITIAWVKPLFDGGAPITGYTVEYKKSDDTDWKTSIQSLRGTEYTISGLTTGA 26151
Query: 1061 EYTVSLVAIK---GNQESPKATGVFTTLQPGSSIPPYNTEVTETTIV-----ITWT---- 1108
EY + ++ + S + + + ++E+ +T IV T T
Sbjct: 26152 EYVFRVKSVNKVGASDPSDSSDPQIAKEREEEPLFDIDSEMRKTLIVKAGASFTMTVPFR 26211
Query: 1109 --PAPRIGFKLGVRPSQG--GEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDA 1164
P P + L +P A + T S+ + YT+ +
Sbjct: 26212 GRPVPNV---LWSKPDTDLRTRAYVDTTDSRTSLTIENANRNDSGKYTLTIQNVLSAASL 26268
Query: 1165 PIVNKVVTPLSPPTNLHLE-ANPDTGVLTVSW---ERSTTPDITGYRITTTPTNGQQGNS 1220
+V KV+ PPTN+ ++ ++ VL SW E + Y I + + S
Sbjct: 26269 TLVVKVLDTPGPPTNITVQDVTKESAVL--SWDVPENDGGAPVKNYHIEKREASKKAWVS 26326
Query: 1221 LE--------EVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPEVPQLTD 1272
+ +V + + + + +S E+ V + + KE V I++ P P+
Sbjct: 26327 VTNNCNRLSYKVTNLQEGAIYYFRVSGENEFGVGIPA--ETKEGVKITEK--PSPPE--K 26380
Query: 1273 LSFVDITDSSIGLRWTPLN---SSTIIGYRITVVAAGEGIPIFEDFVDSSVG---YYTVT 1326
L I+ S+ L W S I+ Y + + G+ +++V +V ++ V+
Sbjct: 26381 LGVTSISKDSVSLTWLKPEHDGGSRIVHYVVEALEKGQ-----KNWVKCAVAKSTHHVVS 26435
Query: 1327 GLEPGIDYDISVITLINGGESAPT-----TLTQQTAVPPPTDLRFTNIGPDTMRVTWAPP 1381
GL +Y V G S P L ++ PP D++ N T+ V
Sbjct: 26436 GLRENSEYFFRVFAENQAGLSDPRELLLPVLIKEQLEPPEIDMK--NFPSHTVYVRAGSN 26493
Query: 1382 PSIDLTNFLVRYSPVKNEEDVAELSISPSDNA-VVLTNLLPGTEYVVSVSSVYEQHESTP 1440
+D+ V D L + N + NL + V+ + + +
Sbjct: 26494 LKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADAGRYEITAAN 26553
Query: 1441 LRGRQKTGLD--------SPTG-IDFSDITANSFTVHWIAPR----ATITGYRIRHHPEH 1487
G K ++ PTG + SDIT S T+ W P+ + +T Y + E
Sbjct: 26554 SSGTTKAFINIVVLDRPGPPTGPVVISDITEESVTLKWEPPKYDGGSQVTNYILLKR-ET 26612
Query: 1488 FSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGR------EESPLLIGQQSTVSDV 1541
+ E +R + + LT G EY I A N + + + + T
Sbjct: 26613 STAVWTEVSATVARTMMKVMKLTTGEEYQFRIKAENRFGISDHIDSACVTVKLPYTTPGP 26672
Query: 1542 PRDLEVVAATPTSLLISWDAPAVT----VRYYRITYGETGGNSPVQEFTVPGSKSTATIS 1597
P V T S+ + W P V Y + + + + + ++
Sbjct: 26673 PSTPWVTNVTRESITVGWHEPVSNGGSAVVGYHLEMKDRNSILWQKANKLVIRTTHFKVT 26732
Query: 1598 GLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKW---- 1653
+ G+ Y VYA G S + + P +++TD+ NS+S+ W
Sbjct: 26733 TISAGLIYEFRVYAENAAGVGKPSHPSEPVLAIDACEPPRNVRITDISKNSVSLSWQQPA 26792
Query: 1654 LPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE-S 1712
S +TGY V TK +T+ I GL +Y V+A+N G S
Sbjct: 26793 FDGGSKITGYIVERRDLPDGRWTKASFTNVTETQFIISGLTQNSQYEFRVFARNAVGSIS 26852
Query: 1713 QPL-VQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAP 1771
P V +T ID G D+ ++ ++ + G + R S E +
Sbjct: 26853 NPSEVVGPITCIDSYGGPVI-DLPLEYTEVV-KYRAGTSVKLRAGISGKPAPTIEWYK-D 26909
Query: 1772 DGEEDTAELQGLRPGSEYTVSVVALHDDMES-------QPLIGTQSTAI---------PA 1815
D E T L + ++ ++ D + S + +G+ S I P
Sbjct: 26910 DKELQTNALVCVENTTDLASILIKDADRLNSGCYELKLRNAMGSASATIRVQILDKPGPP 26969
Query: 1816 PTDLKFTQVTPTSLSAQWTPP----NVQLTGYRVRVTPKEKTGPM--KEINLAPDSSSVV 1869
++F VT ++ W PP ++T Y + K +T + ++ + +
Sbjct: 26970 GGPIEFKTVTAEKITLLWRPPADDGGAKITHY---IVEKRETSRVVWSMVSEHLEECIIT 27026
Query: 1870 VSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENV----SPPRRARVTDATETTITISW 1925
+ ++ +Y V A+ P + +N PP VT T+ ++T+ W
Sbjct: 27027 TTKIIKGNEYIFRVRAVNKYGIGEPLESDSVVAKNAFVTPGPPGIPEVTKITKNSMTVVW 27086
Query: 1926 RTKT----ETITGFQV---DAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLN 1978
I+G+ + D ++ TI+ D R +TGL +DY+ + +N
Sbjct: 27087 SRPIADGGSDISGYFLEKRDKKSLGWFKVLKETIR-DTRQ-KVTGLTENSDYQYRVCAVN 27144
Query: 1979 DNAR---SSPVVI-DASTAIDAP---SNLRFLATTPNSLLVSWQPP----RARITGYIIK 2027
+ S P A+ ID P + +R +T +S+ + W P + +TGY+++
Sbjct: 27145 AAGQGPFSEPSEFYKAADPIDPPGPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVVE 27204
Query: 2028 YEKPGSPPREVVP-RPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPL 2076
+ V + TE ++ L+PG Y V A+ + EP+
Sbjct: 27205 IRQGEEEEWTTVSTKGEVRTTEYVVSNLKPGVNYYFRVSAVNCAGQGEPI 27254
Score = 114 bits (286), Expect = 9e-25
Identities = 308/1475 (20%), Positives = 520/1475 (35%), Gaps = 204/1475 (13%)
Query: 806 SQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ----APITGYRIVYSPSVEGS-STELNLPE 860
S+ P P + T+ V+ + + W P+ A IT Y I T + +
Sbjct: 13186 SKYDVPGPPLNVTITDVNRFGVSLTWEPPEYDGGAEITNYVIELRDKTSIRWDTAMTVRA 13245
Query: 861 TANSVTLSDLQPGVQYNITIYA-----VEENQESTPVVIQQETTGTPRSDTVPSPRDLQF 915
S T++D+ G +Y+ + A V + +TP V + P P +L
Sbjct: 13246 EDLSATVTDVVEGQEYSFRVRAQNRIGVGKPSAATPFVKVADPIERPSP-----PVNLTS 13300
Query: 916 VEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGV 971
+ T V + W PP S + GY ++ + + +VTGL G
Sbjct: 13301 SDQTQSSVQLKWEPPLKDGGSPILGYIIERCEEGKDNWIRCNMKLVPELTYKVTGLEKGN 13360
Query: 972 TYYFKVFAVSHGRESKP------LTA-----QQTTKLDA-PTNLQFVNETDSTVLVRWTP 1019
Y ++V A + S P LTA + T L A L+ + T+LV T
Sbjct: 13361 KYLYRVSAENKAGVSDPSEILGPLTADDAFVEPTMDLSAFKDGLEVIVPNPITILVPSTG 13420
Query: 1020 -PRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKA 1078
PR T L + + ++S Y + P+ + +K
Sbjct: 13421 YPRPTATWCFGDKVLETGDRVKM----KTLSAYAELVISPSERSDKGIYTLKLENRVKTI 13476
Query: 1079 TG---VFTTLQPGSSIPPYNTEVTETTIVITWTP------APRIGFKLGVRPSQGGEAPR 1129
+G V +P + ++T+ ++ +TW P +P G+ + R E R
Sbjct: 13477 SGEIDVNVIARPSAPKELKFGDITKDSVHLTWEPPDDDGGSPLTGYVVEKR-----EVSR 13531
Query: 1130 EVTSDSGSIV------VSGLTPGVEYVYTIQVLRDGQERDAPIVNKVV---TPLS---PP 1177
+ + V V L G EY++ + + V++ V TP + PP
Sbjct: 13532 KTWTKVMDFVTDLEFTVPDLVQGKEYLFKVCARNKCGPGEPAYVDEPVNMSTPATVPDPP 13591
Query: 1178 TNLHLEANPDTGVLTVSWERSTTPD---ITGYRITTTPTNGQQGNSLEEVVHADQSSCTF 1234
N+ + ++W+ I GY + P + + E V + T
Sbjct: 13592 ENVKWRDRTANSIF-LTWDPPKNDGGSRIKGYIVERCPRGSDKWVACGEPVAETKMEVT- 13649
Query: 1235 DNLSPGLEYNVSVYTVKDDKESVPISDT-------------IIPEVPQLTDLSF-----V 1276
L G Y V + S P T I +V L L+ +
Sbjct: 13650 -GLEEGKWYAYRVKALNRQGASKPSRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKI 13708
Query: 1277 DITDSSIG-----LRWTPLNSSTIIGYRITVVAAGEGIP-----IFEDFVDSSVGYYTVT 1326
++ + G + WT + RIT+ E +P D S G Y +
Sbjct: 13709 ELPATVTGKPEPKITWTKADMILKQDKRITI----ENVPKKSTVTIVDSKRSDTGTYIIE 13764
Query: 1327 GLEPGIDYDISVITLINGGESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAPPPS--- 1383
+ + G +A + PP T++ ++ +TW PP
Sbjct: 13765 AVN------------VCGRATAVVEVNVLDKPGPPAAFDITDVTNESCLLTWNPPRDDGG 13812
Query: 1384 IDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSS-----VYEQHES 1438
+TN++V +E +LS + D T L+P EY+ V++ V E ++
Sbjct: 13813 SKITNYVVERRATDSEV-WHKLSSTVKDTNFKATKLIPNKEYIFRVAAENMYGVGEPVQA 13871
Query: 1439 TPLRGR-QKTGLDSPTGIDFSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPR 1493
+P+ + Q PT ++ SDIT ++ T+ W P + ITGY + R
Sbjct: 13872 SPITAKYQFDPPGPPTRLEPSDITKDAVTLTWCEPDDDGGSPITGYWVERLDPDTDKWVR 13931
Query: 1494 EDRVPHSRNSITLTNLTPGTEYVVSIVALN-------GREESPLLIGQQSTVSDVPRDLE 1546
+++P + + LT +Y ++A N + P+LI P
Sbjct: 13932 CNKMPVKDTTYRVKGLTNKKKYRFRVLAENLAGPGKPSKSTEPILIKDPIDPPWPPGKPT 13991
Query: 1547 VVAATPTSLLISWDAP----AVTVRYYRITYGETGGNSPVQEFTVPGSKSTA-TISGLKP 1601
V TS+ ++W P + Y I +TG + V+ G +T + GL
Sbjct: 13992 VKDVGKTSVRLNWTKPEHDGGAKIESYVIEMLKTGTDEWVR--VAEGVPTTQHLLPGLME 14049
Query: 1602 GVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQ---MQVTDVQDNSISVKWL---- 1654
G +Y+ V AV G+S S + R ++ PS ++V ++ N+ +KW
Sbjct: 14050 GQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLEVINITKNTADLKWTVPEK 14109
Query: 1655 PSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQ- 1713
SP+T Y V G T D T+ T+ L YV V A+N G+S
Sbjct: 14110 DGGSPITNYIVEKRDVRRKGWQTVDTTVKD-TKCTVTPLTEGSLYVFRVAAENAIGQSDY 14168
Query: 1714 ------PLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQ----VSRYRVTYSSPEDG 1763
L + T P LA DV + + WE P+ + RY +
Sbjct: 14169 TEIEDSVLAKDTFTTPGPPYALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKERLGT 14228
Query: 1764 IHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPT------ 1817
G + + + G+E V A ++ P T+ +I PT
Sbjct: 14229 RWVKAGKTAGPDCNFRVTDVIEGTEVQFQVRAENEAGVGHPSEPTEILSIEDPTSPPSPP 14288
Query: 1818 -DLKFTQVTPTSLSAQWTPPNVQ----LTGYRVRVTPKEKTGPMKEINLAP--DSSSVVV 1870
DL T ++ W PP + GY V + P T +N P D V
Sbjct: 14289 LDLHVTDAGRKHIAIAWKPPEKNGGSPIIGYHVEMCP-VGTEKWMRVNSRPIKDLKFKVE 14347
Query: 1871 SGLMVATKYEVSVYALKDTLTSRP---AQGVVTTLENVSP-----PRRARVTDATETTIT 1922
G++ +Y + V A+ S P ++ VV + P V + + +I
Sbjct: 14348 EGVVPDKEYVLRVRAVNAIGVSEPSEISENVVAKDPDCKPTIDLETHDIIVIEGEKLSIP 14407
Query: 1923 ISWRTKTETITGFQVDAVPANGQTPIQRTIKPD-VRSYTITGLQPGTDYKIYLYTLNDNA 1981
+ +R + D + T+K D + ++ D IY TL +
Sbjct: 14408 VPFRAVPVPTVSWHKDGKEVKASDRL--TMKNDHISAHLEVPKSVRADAGIYTITLENKL 14465
Query: 1982 RSSPVVIDAST-AIDAP-SNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPP 2035
S+ I+ + P +++ T +S ++W+PP I Y+++ + G
Sbjct: 14466 GSATASINVKVIGLPGPCKDIKASDITKSSCKLTWEPPEFDGGTPILHYVLERREAGR-- 14523
Query: 2036 REVVP-RPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELPQLVTLPHP 2094
R +P T+ L P EY V A+ +G + EL V P
Sbjct: 14524 RTYIPVMSGENKLSWTVKDLIPNGEYFFRVKAVNK-------VGGGEYIELKNPVIAQDP 14576
Query: 2095 NLHGPEILDV----PSTVQKTPFVTHPGYDTGNGI 2125
+DV P+ T P YD G+ I
Sbjct: 14577 KQPPDPPVDVEVHNPTAEAMTITWKPPLYDGGSKI 14611
Score = 114 bits (286), Expect = 9e-25
Identities = 280/1356 (20%), Positives = 495/1356 (36%), Gaps = 217/1356 (16%)
Query: 727 SVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQ--YLDLPSTA--TSVNIPDLLP 782
+VTE+T+ V+SW D G ++++ + ++ + + + ++ S T + + LL
Sbjct: 21563 AVTEVTSEKCVLSWFPPLDD-GGAKIDHYIVQKRETSRLAWTNVASEVQVTKLKVTKLLK 21621
Query: 783 GRKYI-----VNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAP 837
G +YI VN Y + E E +L+ + PD P +P V + S+VV W P +
Sbjct: 21622 GNEYIFRVMAVNKYGVGEPLESEPVLAVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDS- 21680
Query: 838 ITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQ-------PGVQYNITIYAVEENQEST 890
G + + VE N TL+DL+ G +Y I A S
Sbjct: 21681 -DGGSEIINYIVERRDKAGQRWIKCNKKTLTDLRYKVSGLTEGHEYEFRIMAENAAGISA 21739
Query: 891 PVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNL 946
P P + + ++ + ++I W P S +TGY V++ L
Sbjct: 21740 PSPTSPFYKACDTVFKPGPPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIA---L 21796
Query: 947 PGEHGQRLPIS----RNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLD---A 999
P E ++ + T +TGL+ Y +++A++ +P T K +
Sbjct: 21797 PEEDEWQIVTPPAGLKATSYTITGLTENQEYKIRIYAMNSEGLGEPALVPGTPKAEDRML 21856
Query: 1000 PTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPR---QYNVGPSVSKYPLRNL 1056
P ++ + V +R RL V + R P + G S+ K ++
Sbjct: 21857 PPEIELDADLRKVVTIR------ACCTLRLFVPIKGRPAPEVKWARDHGESLDK---ASI 21907
Query: 1057 QPASEYTVSLVAIKGNQESPK----------ATGVFTTLQ----PGSSIPPYNTEVTETT 1102
+ S YT+ +V +S K + F ++ PG EVT+T+
Sbjct: 21908 ESTSSYTLLIVGNVNRFDSGKYILTVENSSGSKSAFVNVRVLDTPGPPQDLKVKEVTKTS 21967
Query: 1103 IVITWTPAPRI--GFKLGVRPSQGGEAPREVTS------DSGSIVVSGLTPGVEYVYTIQ 1154
+ +TW P P + G K+ + E+ R+ S S V L G Y + +
Sbjct: 21968 VTLTWDP-PLLDGGSKIKNYIVEKRESTRKAYSTVATNCHKTSWKVDQLQEGCSYYF--R 22024
Query: 1155 VLRDGQ------ERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPD---ITG 1205
VL + + A V PL P ++ ++ +++SWE+ I G
Sbjct: 22025 VLAENEYGIGLPAETAESVKASERPLPPGKITLMDVTRNS--VSLSWEKPEHDGGSRILG 22082
Query: 1206 YRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYT-----VKDDKE-SVPI 1259
Y I T G + V +++ T L G EY+ V + D ++ SVP+
Sbjct: 22083 Y-IVEMQTKGSDKWATCATVKVTEATIT--GLIQGEEYSFRVSAQNEKGISDPRQLSVPV 22139
Query: 1260 --SDTIIPEVPQLTDLSFVDITDSSI------------GLRW----TPLNSSTIIGYRIT 1301
D +IP +L +F + + + W PL +T + T
Sbjct: 22140 IAKDLVIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAEST 22199
Query: 1302 VVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTL---TQQTAV 1358
+ +D VG+Y V+ L N A TL
Sbjct: 22200 ---ENNSLLTIKDACREDVGHY--------------VVKLTNSAGEAIETLNVIVLDKPG 22242
Query: 1359 PPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAE---LSISPSDNAVV 1415
PP ++ + D++ ++W PP D + + Y K + +S + + +
Sbjct: 22243 PPTGPVKMDEVTADSITLSWG-PPKYDGGSSINNYIVEKRDTSTTTWQIVSATVARTTIK 22301
Query: 1416 LTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTG-----LDSPTGIDFSDITA-NSFTVHW 1469
L G EY +++ +ST L + P G +++ +S V W
Sbjct: 22302 ACRLKTGCEYQFRIAAENRYGKSTYLNSEPTVAQYPFKVPGPPGTPVVTLSSRDSMEVQW 22361
Query: 1470 IAP----RATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGR 1525
P + + GY + + + ++ P + T L G EY + A
Sbjct: 22362 NEPISDGGSRVIGYHLERKERNSILWVKLNKTPIPQTKFKTTGLEEGVEYEFRVSA---- 22417
Query: 1526 EESPLLIGQQSTVSD--VPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQ 1583
E+ + IG+ S VS+ V RD P +++++ + +VT+++ + TY G S +
Sbjct: 22418 -ENIVGIGKPSKVSECYVARDPCDPPGRPEAIIVTRN--SVTLQWKKPTY---DGGSKIT 22471
Query: 1584 EFTVPGS--------KSTAT--------ISGLKPGVDYTITVYAVTGRG-DSPASSKPIS 1626
+ V K++ T ++GL Y V A G S S +
Sbjct: 22472 GYIVEKKELPEGRWMKASFTNIIDTHFEVTGLVEDHRYEFRVIARNAAGVFSEPSESTGA 22531
Query: 1627 INYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQT 1686
I R E+D P +D + ++V P PT G +
Sbjct: 22532 ITARDEVDPPRISMDPKYKDTIV-------VHAGESFKVDADIYGKPIPTIQWIKGDQEL 22584
Query: 1687 EMTIEGLQPTVEYVVS---------------VYAQNPSGESQPLVQTAVTNIDRP----K 1727
T + ++ S + A+N +GE V V +DRP
Sbjct: 22585 SNTARLEIKSTDFATSLSVKDAVRVDSGNYILKAKNVAGERSVTVNVKV--LDRPGPPEG 22642
Query: 1728 GLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHEL-FPAPDGEEDT--AELQGLR 1784
+ + V + +AW+ P + Y L + D T ++ L
Sbjct: 22643 PVVISGVTAEKCTLAWKPPLQDGGSDIINYIVERRETSRLVWTVVDANVQTLSCKVTKLL 22702
Query: 1785 PGSEYTVSVVALH-----DDMESQPLIGTQSTAIP-APTDLKFTQVTPTSLSAQWTPP-- 1836
G+EYT ++A++ + +ES+P++ +P AP + T VT S+ W P
Sbjct: 22703 EGNEYTFRIMAVNKYGVGEPLESEPVVAKNPFVVPDAPKAPEVTTVTKDSMIVVWERPAS 22762
Query: 1837 --NVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRP 1894
++ GY + KE + + V+GL+ YE V A S P
Sbjct: 22763 DGGSEILGYVLEKRDKEGIRWTRCHKRLIGELRLRVTGLIENHDYEFRVSAENAAGLSEP 22822
Query: 1895 A-----QGVVTTLENVSPPRRARVTDATETTITISW 1925
+ Q + PP +V D T +++ +SW
Sbjct: 22823 SPPSAYQKACDPIYKPGPPNNPKVIDITRSSVFLSW 22858
Score = 114 bits (284), Expect = 2e-24
Identities = 358/1658 (21%), Positives = 597/1658 (36%), Gaps = 251/1658 (15%)
Query: 607 SSSGPVEVFIT----ETPSQPNSHPIQWNAPQPSHISKYILRWRP---------KNSVGR 653
+SSG F+T +TP P + ++ + L W P KN V
Sbjct: 24099 NSSGSKSAFVTVKVLDTPGPPQNLAVKEVRKDSA-----FLVWEPPIIDGGAKVKNYVID 24153
Query: 654 WKEATIPGHLN--------SYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTP 705
+E+T + N S+ ++ L G +Y ++++ ++G P
Sbjct: 24154 KRESTRKAYANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFG-------------VGVP 24200
Query: 706 VTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVS----ASDTVSGFRVEYELSEEGD 761
V + P SP ++T+++ +S + W V G+ VE + +G
Sbjct: 24201 VETVDAVKAAEPPSP--PGKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVE--MQPKGT 24256
Query: 762 EPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQ 821
E + S + + L G++Y V +E G+ + A D P++
Sbjct: 24257 EKWSIVAESKVCNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKL 24316
Query: 822 VDDTSIVVRWS--RPQAPITGY-RIVYSPSVEGS----STELNLPETANSVTLSDLQPGV 874
+T + + + P+ G R S +G +T +N+ ETA S L ++ G
Sbjct: 24317 PFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLH-IKEGN 24375
Query: 875 QYNITIYAVEENQESTPV-----VIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTP 929
+ + Y V + VI E G P ++F EV+ V I W P
Sbjct: 24376 KDDFGKYTVTATNSAGTATENLSVIVLEKPGPPVGP-------VRFDEVSADFVVISWEP 24428
Query: 930 PESA----VTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRE 985
P ++ Y V+ H ++R T ++T L G Y F++FA + +
Sbjct: 24429 PAYTGGCQISNYIVEKRDTTTTTWHMVSATVARTTI-KITKLKTGTEYQFRIFAENRYGK 24487
Query: 986 SKPLTA-----QQTTKLDAPTNLQFVNE-TDSTVLVRWTPP----RAQITGYRLTVGLTR 1035
S PL + Q K P FV + +LV+W P +I GY L
Sbjct: 24488 SAPLDSKAVIVQYPFKEPGPPGTPFVTSISKDQMLVQWHEPVNDGGTKIIGYHLEQKEKN 24547
Query: 1036 RGQPRQYNVGP-SVSKYPLRNLQPASEY--TVSLVAIKGNQESPKATGVFTTLQPGSSIP 1092
+ N P +K+ L EY VS I G + K + F P P
Sbjct: 24548 SILWVKLNKTPIQDTKFKTTGLDEGLEYEFKVSAENIVGIGKPSKVSECFVARDPCD--P 24605
Query: 1093 PYNTE---VTETTIVITW-TPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVE 1148
P E +T + + W PA G K+ G + G + + T +E
Sbjct: 24606 PGRPEAIVITRNNVTLKWKKPAYDGGSKI------TGYIVEKKDLPDGRWMKASFTNVLE 24659
Query: 1149 YVYTIQVLRDGQERDAPIV-NKVVTPLSPPT---------------NLHLEAN-PDTGVL 1191
+T+ L + Q + ++ S P+ N L+ D V+
Sbjct: 24660 TEFTVSGLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARDEIDAPNASLDPKYKDVIVV 24719
Query: 1192 TVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNL---------SPGLE 1242
DI G I + + G LEE + T + G +
Sbjct: 24720 HAGETFVLEADIRGKPIPDVVWS-KDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQ 24778
Query: 1243 YNVSVYTVKDDKESVPISDTIIPEV-PQLTDLSFVDITDSSIGLRWTP--LNSSTIIGYR 1299
Y + + V K S+PI+ ++ P L +T L W P + I +
Sbjct: 24779 YILKLSNVGGTK-SIPITVKVLDRPGPPEGPLKVTGVTAEKCYLAWNPPLQDGGANISHY 24837
Query: 1300 ITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGG-----ESAPTTLTQ 1354
I + + + Y VT L PG +Y V+ + G ES P T
Sbjct: 24838 IIEKRETSRLSWTQVSTEVQALNYKVTKLLPGNEYIFRVMAVNKYGIGEPLESGPVTACN 24897
Query: 1355 QTAVP-PPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISP---S 1410
P PP+ + I D+M VTWA P T +++E V + +
Sbjct: 24898 PYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDKEGVRWTKCNKKTLT 24957
Query: 1411 DNAVVLTNLLPGTEYVVSVSS-----VYEQHESTPLRGRQKTGL---DSPTGIDFSDITA 1462
D + +T L G Y V++ V E E + R L P+ +D +
Sbjct: 24958 DLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFY-RACDALYPPGPPSNPKVTDTSR 25016
Query: 1463 NSFTVHWIAP----RATITGYRIRHHPEHFSGRPREDRVPHS---RNSITLTNLTPGTEY 1515
+S ++ W P A + GY + + + P + T+T L TEY
Sbjct: 25017 SSVSLAWSKPIYDGGAPVKGYVV--EVKEAAADEWTTCTPPTGLQGKQFTVTKLKENTEY 25074
Query: 1516 VVSIVALN--GREESPLLIGQQSTVSDV-PRDLEVVAATPTSLLISWDAPAVTVRYYRIT 1572
I A+N G E L G + P ++E+ A +++ A T+R +
Sbjct: 25075 NFRICAINSEGVGEPATLPGSVVAQERIEPPEIELDADLRKVVVLRASA---TLRLFVTI 25131
Query: 1573 YGETGGNSPVQEFTVPGSKSTAT-ISGLKPGVDYTITVYAVTGRGDS---------PASS 1622
G P E ++ T + ++ +T+ V R DS + S
Sbjct: 25132 KGR-----PEPEVKWEKAEGILTDRAQIEVTSSFTMLVIDNVTRFDSGRYNLTLENNSGS 25186
Query: 1623 KPISINYRTEIDKPS---QMQVTDVQDNSISVKWLP----SSSPVTGYRV---TTTPKNG 1672
K +N R +D PS + + +V+ +S+++ W P + +T Y V TT K
Sbjct: 25187 KTAFVNVRV-LDSPSAPVNLTIREVKKDSVTLSWEPPLIDGGAKITNYIVEKRETTRK-- 25243
Query: 1673 PGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPK----G 1728
T T +T IE LQ Y V A N G P T + P
Sbjct: 25244 --AYATITNNCTKTTFRIENLQEGCSYYFRVLASNEYGIGLPAETTEPVKVSEPPLPPGR 25301
Query: 1729 LAFTDVDVDSIKIAWESPQ----GQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLR 1784
+ DV ++ I WE P+ +++ Y V + G + + A + GL
Sbjct: 25302 VTLVDVTRNTATIKWEKPESDGGSKITGYVVEMQT--KGSEKWSTCTQVKTLEATISGLT 25359
Query: 1785 PGSEYTVSVVALHDDMESQPL-----IGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQ 1839
G EY V A+++ S P + + I +L F T + + +V
Sbjct: 25360 AGEEYVFRVAAVNEKGRSDPRQLGVPVIARDIEIKPSVELPFH--TFNVKAREQLKIDVP 25417
Query: 1840 LTGYRVRVTPKEKTG-PMKEINLAPDSSSVVVSGLMV--ATKYEVSVYAL--KDTLTSRP 1894
G K G +KE SSS V+ L + A+K +V Y L ++ S
Sbjct: 25418 FKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSNSAGSIT 25477
Query: 1895 AQGVVTTLENVSPPRRARVTDATETTITISWRTKTE----TITGFQVDAVPANGQT---- 1946
+ L+ PP R+ + + +ITISW I+ + V+ T
Sbjct: 25478 VPITIIVLDRPGPPGPIRIDEVSCDSITISWNPPEYDGGCQISNYIVEKKETTSTTWHIV 25537
Query: 1947 --PIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDA-------- 1996
+ RT S I L G++Y+ + N +SS S+A+ A
Sbjct: 25538 SQAVART------SIKIVRLTTGSEYQFRVCAENRYGKSS---YSESSAVVAEYPFSPPG 25588
Query: 1997 -PSNLRFLATTPNSLLVSWQPP----RARITGYIIKYEKPGSPPREVVPRPRPGVTEATI 2051
P + + T +++LV+WQ P +R+ GY ++Y++ S + T+ +
Sbjct: 25589 PPGTPKVVHATKSTMLVTWQVPVNDGGSRVIGYHLEYKERSSILWSKANKILIADTQMKV 25648
Query: 2052 TGLEPGT--EYTIYVIAL----KNNQKSEPLIGRKKTD 2083
+GL+ G EY +Y + K ++ EP+ R D
Sbjct: 25649 SGLDEGLMYEYRVYAENIAGIGKCSKSCEPVPARDPCD 25686
Score = 111 bits (278), Expect = 8e-24
Identities = 306/1510 (20%), Positives = 522/1510 (34%), Gaps = 241/1510 (15%)
Query: 758 EEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLI---LSTSQTTAPDAP 814
E GD + L + A V + P + +Y + + I + + P AP
Sbjct: 13436 ETGDRVKMKTLSAYAELV----ISPSERSDKGIYTLKLENRVKTISGEIDVNVIARPSAP 13491
Query: 815 PDPTVDQVDDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTLSDL 870
+ + S+ + W P +P+TGY + + T++ T T+ DL
Sbjct: 13492 KELKFGDITKDSVHLTWEPPDDDGGSPLTGYVVEKREVSRKTWTKVMDFVTDLEFTVPDL 13551
Query: 871 QPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP 930
G +Y + A + P + + + + P ++++ + T + + W PP
Sbjct: 13552 VQGKEYLFKVCARNKCGPGEPAYVDEPVNMSTPATVPDPPENVKWRDRTANSIFLTWDPP 13611
Query: 931 E----SAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRES 986
+ S + GY V+ P P++ T EVTGL G Y ++V A++ S
Sbjct: 13612 KNDGGSRIKGYIVERCPRGSDKWVACGEPVA-ETKMEVTGLEEGKWYAYRVKALNRQGAS 13670
Query: 987 KP---------------------------LTAQQTTKLDAPTNLQFVNETDSTVLVRWTP 1019
KP LT + TK++ P + E T WT
Sbjct: 13671 KPSRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKIT----WT- 13725
Query: 1020 PRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKAT 1079
+A + + +T P++ V SK Y + V + G +
Sbjct: 13726 -KADMI-LKQDKRITIENVPKKSTVTIVDSK-----RSDTGTYIIEAVNVCGRATAVVEV 13778
Query: 1080 GVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRI--GFKLGVRPSQGGEAPREVTSDSGS 1137
V +PG T+VT + ++TW P PR G K+ + EV S
Sbjct: 13779 NVLD--KPGPPAAFDITDVTNESCLLTWNP-PRDDGGSKITNYVVERRATDSEVWHKLSS 13835
Query: 1138 IV------VSGLTPGVEYVYTI---QVLRDGQERDA-PIVNKV-VTPLSPPTNLHLEANP 1186
V + L P EY++ + + G+ A PI K P PPT L ++
Sbjct: 13836 TVKDTNFKATKLIPNKEYIFRVAAENMYGVGEPVQASPITAKYQFDPPGPPTRLE-PSDI 13894
Query: 1187 DTGVLTVSW---ERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEY 1243
+T++W + ITGY + + + ++ D ++ L+ +Y
Sbjct: 13895 TKDAVTLTWCEPDDDGGSPITGYWVERLDPDTDKWVRCNKMPVKD-TTYRVKGLTNKKKY 13953
Query: 1244 NVSVYTV------KDDKESVP--ISDTIIPEVPQLTDLSFVDITDSSIGLRWTPL---NS 1292
V K K + P I D I P P + D+ +S+ L WT
Sbjct: 13954 RFRVLAENLAGPGKPSKSTEPILIKDPIDPPWPP-GKPTVKDVGKTSVRLNWTKPEHDGG 14012
Query: 1293 STIIGYRITVVAAG--------EGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLING 1344
+ I Y I ++ G EG+P + + + GL G +Y V +
Sbjct: 14013 AKIESYVIEMLKTGTDEWVRVAEGVPTTQ---------HLLPGLMEGQEYSFRVRAVNKA 14063
Query: 1345 GESAPT-----TLTQQTAVP--PPTDLRFTNIGPDTMRVTWAPPP---SIDLTNFLVRYS 1394
GES P+ L ++ P PP L NI +T + W P +TN++V
Sbjct: 14064 GESEPSEPSDPVLCREKLYPPSPPRWLEVINITKNTADLKWTVPEKDGGSPITNYIVEKR 14123
Query: 1395 PVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVS-------SVYEQHESTPLRGRQKT 1447
V+ + + + D +T L G+ YV V+ S Y + E + L T
Sbjct: 14124 DVR-RKGWQTVDTTVKDTKCTVTPLTEGSLYVFRVAAENAIGQSDYTEIEDSVLAKDTFT 14182
Query: 1448 GLDSPTGIDFSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRNS 1503
P + D+T + W P+ I Y I + + + +
Sbjct: 14183 TPGPPYALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKERLGTRWVKAGKTAGPDCN 14242
Query: 1504 ITLTNLTPGTEYVVSIVALN----GREESP---LLIGQQSTVSDVPRDLEVVAATPTSLL 1556
+T++ GTE + A N G P L I ++ P DL V A +
Sbjct: 14243 FRVTDVIEGTEVQFQVRAENEAGVGHPSEPTEILSIEDPTSPPSPPLDLHVTDAGRKHIA 14302
Query: 1557 ISWDAPAVTVRYYRITYGETGGNSPVQEFTVP----GSKSTATIS-------------GL 1599
I+W P E G SP+ + V G++ ++ G+
Sbjct: 14303 IAWKPP------------EKNGGSPIIGYHVEMCPVGTEKWMRVNSRPIKDLKFKVEEGV 14350
Query: 1600 KPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSP 1659
P +Y + V AV G S+P I+ P D++ + I V S
Sbjct: 14351 VPDKEYVLRVRAVNAIG----VSEPSEISENVVAKDPDCKPTIDLETHDIIVIEGEKLSI 14406
Query: 1660 VTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYA---------QNPSG 1710
+R P + D+ M + + +E SV A +N G
Sbjct: 14407 PVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLG 14466
Query: 1711 ESQPLVQTAVTNIDRP-KGLAFTDVDVDSIKIAWESPQ--GQVSRYRVTYSSPEDGIHEL 1767
+ + V + P K + +D+ S K+ WE P+ G E G
Sbjct: 14467 SATASINVKVIGLPGPCKDIKASDITKSSCKLTWEPPEFDGGTPILHYVLERREAGRRTY 14526
Query: 1768 FPAPDGEEDTA-ELQGLRPGSEYTVSVVALH-----DDME-SQPLIGTQSTAIP-APTDL 1819
P GE + ++ L P EY V A++ + +E P+I P P D+
Sbjct: 14527 IPVMSGENKLSWTVKDLIPNGEYFFRVKAVNKVGGGEYIELKNPVIAQDPKQPPDPPVDV 14586
Query: 1820 KFTQVTPTSLSAQWTPP----NVQLTGYRV-RVTPKEKTGPMKEINLAPDSSSVVVSGLM 1874
+ T +++ W PP ++ GY + ++ E+ +L P + GL
Sbjct: 14587 EVHNPTAEAMTITWKPPLYDGGSKIMGYIIEKIAKGEERWKRCNEHLVP-ILTYTAKGLE 14645
Query: 1875 VATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTI------------- 1921
+Y+ V A S P++ T + V P +V T +
Sbjct: 14646 EGKEYQFRVRAENAAGISEPSRATPPT-KAVDPIDAPKVILRTSLEVKRGDEIALDASIS 14704
Query: 1922 -----TISWRTKTETITGFQVD--------------------AVPANGQTPIQRTIKPDV 1956
TI+W I ++ +P + I + K +
Sbjct: 14705 GSPYPTITWIKDENVIVPEEIKKRAAPLVRRRKGEVQEEEPFVLPLTQRLSIDNSKKGES 14764
Query: 1957 RSYTITGLQPGTDYKIYLYTL-NDNA-RSSPVVIDASTAIDAPSNLRFLATTPNSLLVSW 2014
+ L+P D+ +Y+ + ND+ +P + P N F S+L W
Sbjct: 14765 QLRVRDSLRP--DHGLYMIKVENDHGIAKAPCTVSVLDTPGPPINFVFEDIRKTSVLCKW 14822
Query: 2015 QPP----RARITGYIIKYEKPGSPPRE-VVPRPRPGVTEATITGLEPGTEYTIYVIALKN 2069
+PP + I Y ++ + P E +V + ++T L G EY V A
Sbjct: 14823 EPPLDDGGSEIINYTLEKKDKTKPDSEWIVVTSTLRHCKYSVTKLIEGKEYLFRVRAENR 14882
Query: 2070 NQKSEPLIGR 2079
P + +
Sbjct: 14883 FGPGPPCVSK 14892
Score = 109 bits (273), Expect = 3e-23
Identities = 290/1404 (20%), Positives = 524/1404 (37%), Gaps = 190/1404 (13%)
Query: 812 DAPPDPT----VDQVDDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETAN 863
D P PT + + + S+ ++W P+ + +T Y ++ + TE++
Sbjct: 26568 DRPGPPTGPVVISDITEESVTLKWEPPKYDGGSQVTNYILLKRETSTAVWTEVSATVART 26627
Query: 864 SVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFV-EVTDVK 922
+ + L G +Y I A EN+ I T P P +V VT
Sbjct: 26628 MMKVMKLTTGEEYQFRIKA--ENRFGISDHIDSACVTVKLPYTTPGPPSTPWVTNVTRES 26685
Query: 923 VTIMWTPPES----AVTGYRVDVIPVN-LPGEHGQRLPISRNTFAEVTGLSPGVTYYFKV 977
+T+ W P S AV GY +++ N + + +L I R T +VT +S G+ Y F+V
Sbjct: 26686 ITVGWHEPVSNGGSAVVGYHLEMKDRNSILWQKANKLVI-RTTHFKVTTISAGLIYEFRV 26744
Query: 978 FAVSHGRESKPL-TAQQTTKLDA---PTNLQFVNETDSTVLVRWTPPR----AQITGYRL 1029
+A + KP ++ +DA P N++ + + ++V + W P ++ITGY
Sbjct: 26745 YAENAAGVGKPSHPSEPVLAIDACEPPRNVRITDISKNSVSLSWQQPAFDGGSKITGYI- 26803
Query: 1030 TVGLTRRGQP-----RQYNVGPSVSKYPLRNLQPASEYTVSLVA--IKGNQESP-KATGV 1081
+ RR P + + +++ + L S+Y + A G+ +P + G
Sbjct: 26804 ---VERRDLPDGRWTKASFTNVTETQFIISGLTQNSQYEFRVFARNAVGSISNPSEVVGP 26860
Query: 1082 FTTLQ----PGSSIPPYNTEVTE----TTIV----ITWTPAPRI-GFKLGVRPSQGGEAP 1128
T + P +P TEV + T++ I+ PAP I +K
Sbjct: 26861 ITCIDSYGGPVIDLPLEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVC 26920
Query: 1129 REVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDT 1188
E T+D SI++ Y +++ A I +++ PP
Sbjct: 26921 VENTTDLASILIKDADRLNSGCYELKLRNAMGSASATIRVQILDKPGPPGGPIEFKTVTA 26980
Query: 1189 GVLTVSWERSTTPD----ITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYN 1244
+T+ W R D IT Y + T+ + + E H ++ T + G EY
Sbjct: 26981 EKITLLW-RPPADDGGAKITHYIVEKRETSRVVWSMVSE--HLEECIITTTKIIKGNEYI 27037
Query: 1245 VSVYTVKDDKESVPI-SDTII----------PEVPQLTDLSFVDITDSSIGLRWT-PL-- 1290
V V P+ SD+++ P +P++T IT +S+ + W+ P+
Sbjct: 27038 FRVRAVNKYGIGEPLESDSVVAKNAFVTPGPPGIPEVT-----KITKNSMTVVWSRPIAD 27092
Query: 1291 NSSTIIGYRITVVAAGEGIPIFEDFVDSSVGYY------------TVTGLEPGIDYDISV 1338
S I GY E S+G++ VTGL DY V
Sbjct: 27093 GGSDISGY------------FLEKRDKKSLGWFKVLKETIRDTRQKVTGLTENSDYQYRV 27140
Query: 1339 ITLINGGE---SAPTTLTQQTAVP-----PPTDLRFTNIGPDTMRVTWAPP---PSIDLT 1387
+ G+ S P+ + A P PP +R + ++ + W+ P +T
Sbjct: 27141 CAVNAAGQGPFSEPSEF-YKAADPIDPPGPPAKIRIADSTKSSITLGWSKPVYDGGSAVT 27199
Query: 1388 NFLVRYSPVKNEE-DVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQ- 1445
++V + EE V++NL PG Y VS+V + P+ +
Sbjct: 27200 GYVVEIRQGEEEEWTTVSTKGEVRTTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEP 27259
Query: 1446 ---KTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRN 1502
K L++P ID S + ++ R P + ++ +R
Sbjct: 27260 VQAKDILEAPE-IDLDVALRTSVIAKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARY 27318
Query: 1503 SI---------TLTNLTPGT--EYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAAT 1551
SI T+ +T +Y+++I G +S + + + L+V +
Sbjct: 27319 SIENTDSSSLLTIPQVTRNDTGKYILTIENGVGEPKSSTVSVKVLDTPAACQKLQVKHVS 27378
Query: 1552 PTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGL-----KPGVDYT 1606
++ + WD P + I Y ++ + ++V K ++T L K +
Sbjct: 27379 RGTVTLLWDPPLIDGGSPIINYVIEKRDATKRTWSVVSHKCSSTSFKLIDLSEKTPFFFR 27438
Query: 1607 ITVYAVTGRGDSPASSKPISINYRTEIDKP-SQMQVTDVQDNSISVKW----LPSSSPVT 1661
+ G G+ +++P+ E+ P + + D S+ + W S +T
Sbjct: 27439 VLAENEIGIGEPCETTEPVK---AAEVPAPIRDLSMKDSTKTSVILSWTKPDFDGGSVIT 27495
Query: 1662 GYRVTTTPKNGPGPTKTKTAGPDQT-EMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAV 1720
Y V + G G AG +T E+ + L+ V+A+N G S P+ +
Sbjct: 27496 EYVV---ERKGKGEQTWSHAGISKTCEIEVSQLKEQSVLEFRVFAKNEKGLSDPVTIGPI 27552
Query: 1721 TNIDRPKGLAFT-DVDVDSIKIAWESPQ-GQVSRYRVTY-SSPEDGIHEL---FPAPDGE 1774
T K L T +VD+ I A + + G + Y P+ I L P + E
Sbjct: 27553 T----VKELIITPEVDLSDIPGAQVTVRIGHNVHLELPYKGKPKPSISWLKDGLPLKESE 27608
Query: 1775 -------EDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPT----DLKFTQ 1823
E+ L E+ + D+ + + + P+ ++F +
Sbjct: 27609 FVRFSKTENKITLSIKNAKKEHGGKYTVILDNAVCRIAVPITVITLGPPSKPKGPIRFDE 27668
Query: 1824 VTPTSLSAQWTPP----NVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKY 1879
+ S+ W P ++T Y + +T K + + ++ V L+ +Y
Sbjct: 27669 IKADSVILSWDVPEDNGGGEITCYSIEKRETSQTN-WKMVCSSVARTTFKVPNLVKDAEY 27727
Query: 1880 EVSVYALKDTLTSRPAQGVVTTLEN----VSPPRRARVTDATETTITISWRTKT----ET 1931
+ V A S+P + ++ PP + + + T ++++W
Sbjct: 27728 QFRVRAENRYGVSQPLVSSIIVAKHQFRIPGPPGKPVIYNVTSDGMSLTWDAPVYDGGSE 27787
Query: 1932 ITGFQVDAVPANGQTPIQRTIKP-DVRSYTITGLQPGTDYKIYLYTLNDNARSSP----V 1986
+TGF V+ N + P R Y TGL G DY+ +Y N SSP
Sbjct: 27788 VTGFHVEKKERNSILWQKVNTSPISGREYRATGLVEGLDYQFRVYAENSAGLSSPSDPSK 27847
Query: 1987 VIDASTAIDAPSNLRFLATTPNSLLVSWQPP----RARITGYIIKYEKPGSPPREVVPRP 2042
A + +D P ++ T ++ + W PP ++I GY I+ ++ G+
Sbjct: 27848 FTLAVSPVDPPGTPDYIDVTRETITLKWNPPLRDGGSKIVGYSIE-KRQGNERWVRCNFT 27906
Query: 2043 RPGVTEATITGLEPGTEYTIYVIA 2066
+ T+TGL PG Y +IA
Sbjct: 27907 DVSECQYTVTGLSPGDRYEFRIIA 27930
Score = 109 bits (272), Expect = 4e-23
Identities = 299/1423 (21%), Positives = 501/1423 (35%), Gaps = 243/1423 (17%)
Query: 728 VTEITASSFVVSW----VSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPG 783
+++I A + +SW ++ + VE GD L T TS + L+PG
Sbjct: 19001 ISDIDADACSLSWHIPLEDGGSNITNYIVEKCDVSRGDWVTAL-ASVTKTSCRVGKLIPG 19059
Query: 784 RKYIVNV-----YQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ--- 835
++YI V + ISE +++ P P + V +V+ I V W RP
Sbjct: 19060 QEYIFRVRAENRFGISEPLTSPKMVAQFPFGVPSEPKNARVTKVNKDCIFVAWDRPDSDG 19119
Query: 836 -APITGYRIVYSPS-----VEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQES 889
+PI GY I V+ + T + E + L G++Y+ IYA+ + S
Sbjct: 19120 GSPIIGYLIERKERNSLLWVKANDTLVRSTE----YPCAGLVEGLEYSFRIYALNKAGSS 19175
Query: 890 TPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPVN 945
P + T D P + ++VT V+++W P+ S + GY V+
Sbjct: 19176 PPSKPTEYVTARMPVDPPGKP---EVIDVTKSTVSLIWARPKHDGGSKIIGYFVEA--CK 19230
Query: 946 LPGEHGQRLPISRNTFAE----VTGLSPGVTYYFKVF---AVSHGRESKPLTAQQTTKLD 998
LPG+ R + + + TGL Y F+ AV+ S+P +
Sbjct: 19231 LPGDKWVRCNTAPHQIPQEEYTATGLEEKAQYQFRAIARTAVNISPPSEPSDPVTILAEN 19290
Query: 999 APTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQ----------YNVGPSV 1048
P + S + V+ G + + T G+P +
Sbjct: 19291 VPPRIDLSVAMKSLLTVK--------AGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGI 19342
Query: 1049 SKYPLRNL----------QPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEV 1098
RNL + + +YT++ G++ + V +PG PP + ++
Sbjct: 19343 KMAMQRNLCTLELFSVNRKDSGDYTITAENSSGSKSATIKLKVLD--KPG---PPASVKI 19397
Query: 1099 TE---TTIVITWTPAPRIG------FKLGVR-PSQGGEAPREVTSDSGSIVVSGLTPGVE 1148
+ +++W P G + + R S+ A T S V L G E
Sbjct: 19398 NKMYSDRAMLSWEPPLEDGGSEITNYIVDKRETSRPNWAQVSATVPITSCSVEKLIEGHE 19457
Query: 1149 YVYTIQVLRDGQERDAPIVNKVV--TPLSPPTNLH--LEANPDTGVLTVSWERSTT---P 1201
Y + I D + P PP + +N +TVSW+
Sbjct: 19458 YQFRICAENKYGVGDPVFTEPAIAKNPYDPPGRCDPPVISNITKDHMTVSWKPPADDGGS 19517
Query: 1202 DITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTV--------KDD 1253
ITGY + T + ++ + L G EY V + D
Sbjct: 19518 PITGYLLEKRETQAVNWTKVNRKPIIER-TLKATGLQEGTEYEFRVTAINKAGPGKPSDA 19576
Query: 1254 KESVPISDTIIPEVPQLTDLSFVDITDSSIGLRWTPL---NSSTIIGYRITVVAAGEGIP 1310
++ D P P + D T SS+ L W S IIGY + V A
Sbjct: 19577 SKAAYARDPQYPPGPPAFPKVY-DTTRSSVSLSWGKPAYDGGSPIIGYLVEVKRADS--- 19632
Query: 1311 IFEDFVDSSVGY------YTVTGLEPGIDYDISVITLINGGESAPTTL-----TQQTAVP 1359
+++V ++ + VTGL Y V + G S P+ + + +P
Sbjct: 19633 --DNWVRCNLPQNLQKTRFEVTGLMEDTQYQFRVYAVNKIGYSDPSDVPDKHYPKDILIP 19690
Query: 1360 P----PTDLRFTNI--GPDTMR----VTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISP 1409
P DLR T I TMR V PPP I + P N D L I
Sbjct: 19691 PEGELDADLRKTLILRAGVTMRLYVPVKGRPPPKITWS------KPNVNLRDRIGLDIKS 19744
Query: 1410 SDNAVVL----TNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSF 1465
+D L N +Y++++ + + E T + T P + +I+ +S
Sbjct: 19745 TDFDTFLRCENVNKYDAGKYILTLENSCGKKEYTIVVKVLDTP-GPPVNVTVKEISKDSA 19803
Query: 1466 TVHWIAP----RATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVA 1521
V W P + I Y ++ S+ S + NL G Y + A
Sbjct: 19804 YVTWEPPIIDGGSPIINYVVQKRDAERKSWSTV-TTECSKTSFRVANLEEGKSYFFRVFA 19862
Query: 1522 LNGREESPLLIGQQSTVSDVPR---------DLEVVAATPTSLLISWDAPAVTVRYYRIT 1572
E+ IG D + DL+V + + +S I W P I
Sbjct: 19863 -----ENEYGIGDPGETRDAVKASQTPGPVVDLKVRSVSKSSCSIGWKKPHSDGGSRIIG 19917
Query: 1573 YGETGGNSPVQEFTVPGSKSTATISGLK---------PGVDYTITVYAVTGRGDSPASSK 1623
Y V +F +K + L G +YT V A G+ S
Sbjct: 19918 Y--------VVDFLTEENKWQRVMKSLSLQYSAKDLTEGKEYTFRVSAENENGEGTPSE- 19968
Query: 1624 PISINYRTEIDKPSQMQVTDVQDNSISVKWLPS----SSPVTGYRVTTTPKNGPGPTKTK 1679
I++ R ++ P + +K LP + + +R+ K P P+ +
Sbjct: 19969 -ITVVARDDVVAP-----------DLDLKGLPDLCYLAKENSNFRLKIPIKGKPAPSVSW 20016
Query: 1680 TAGPD----QTEMTIEGLQPTVEYVV-----------SVYAQNPSGESQPLVQTAVTNID 1724
G D T +++E +V ++ +N +G + + V
Sbjct: 20017 KKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKEGTISIKVVGKP 20076
Query: 1725 R-PKG-LAFTDVDVDSIKIAWESPQGQVSRYRVTY-SSPEDGIHELFP--APDGEEDTAE 1779
P G + F +V +++ + W P+ Y D ++ + A ++ T
Sbjct: 20077 GIPTGPIKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDSVNNKWVTCASAVQKTTFR 20136
Query: 1780 LQGLRPGSEYTVSVVA-----LHDDMESQPLIGTQSTAIP-APTDLKFTQVTPTSLSAQW 1833
+ L G EYT V A + + ++S+P++ +P AP V S+S W
Sbjct: 20137 VTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVPDAPPPPNIVDVRHDSVSLTW 20196
Query: 1834 TPP----NVQLTGYRVRVTPKEKTGPM-KEINLAP-DSSSVVVSGLMVATKYEVSVYAL- 1886
T P +TGY + KE+ + K N P V+GL +YE V A+
Sbjct: 20197 TDPKKTGGSPITGYHLEF--KERNSLLWKRANKTPIRMRDFKVTGLTEGLEYEFRVMAIN 20254
Query: 1887 -----KDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKT----ETITGFQV 1937
K +L S P V L+ + PP + V + T ++T+ W +TG+ V
Sbjct: 20255 LAGVGKPSLPSEP----VVALDPIDPPGKPEVINITRNSVTLIWTEPKYDGGHKLTGYIV 20310
Query: 1938 DA--VPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLN 1978
+ +P+ P+ ++T+T L G Y+ + N
Sbjct: 20311 EKRDLPSKSWMKANHVNVPEC-AFTVTDLVEGGKYEFRIRAKN 20352
Score = 108 bits (269), Expect = 9e-23
Identities = 265/1341 (19%), Positives = 468/1341 (34%), Gaps = 163/1341 (12%)
Query: 780 LLPGRKYIVNVYQISEDGE----QSLILSTSQTTAPDAPPD-PTVDQVDDTSIVVRWSRP 834
L+ G +YI V ++ G+ QS + P PP+ P V V + V W RP
Sbjct: 20536 LIQGNEYIFRVSAVNHYGKGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSWKRP 20595
Query: 835 Q----APITGYRIVYSPSVEGSSTE-LNLPETANSVTLSDLQPGVQYNITIYA-----VE 884
+ ITGY + + P + ++ LQ G Y + A +
Sbjct: 20596 VDDGGSEITGYHVERREKKSLRWVRAIKTPVSDLRCKVTGLQEGSTYEFRVSAENRAGIG 20655
Query: 885 ENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPES----AVTGYRVD 940
E++ V+ ++ P + P D T ++ W P +TGY V+
Sbjct: 20656 PPSEASDSVLMKDAAYPPGPPSNPHVTD-----TTKKSASLAWGKPHYDGGLEITGYVVE 20710
Query: 941 VIPVN----LPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQ--QT 994
V + G L I++ V L Y F++ A++ +P +
Sbjct: 20711 HQKVGDEAWIKDTTGTALRITQFV---VPDLQTKEKYNFRISAINDAGVGEPAVIPDVEI 20767
Query: 995 TKLDAPTNLQFVNETDSTVLVR-------WTP----PRAQITGYRLTVGLTRRGQPRQYN 1043
+ + + + E T++VR + P P ++T + + L R
Sbjct: 20768 VEREMAPDFELDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKNRANIENTE 20827
Query: 1044 VGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTI 1103
++ P N ++ +++ G + V T P ++ P T++T+ ++
Sbjct: 20828 -SFTLLIIPECNRYDTGKFVMTIENPAGKKSGFVNVRVLDTPGPVLNLRP--TDITKDSV 20884
Query: 1104 VITWT-PAPRIGFKLGVRPSQGGEAPREVTSDSGS------IVVSGLTPGVEYVYTIQVL 1156
+ W P G ++ + EA R+ S + + V+GL+ G EY + +
Sbjct: 20885 TLHWDLPLIDGGSRITNYIVEKREATRKSYSTATTKCHKCTYKVTGLSEGCEYFFRVMAE 20944
Query: 1157 RD---GQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPD---ITGYRITT 1210
+ G+ + K SPP +L++ + ++++W + ITGY I
Sbjct: 20945 NEYGIGEPTETTEPVKASEAPSPPDSLNI-MDITKSTVSLAWPKPKHDGGSKITGYVIEA 21003
Query: 1211 TPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISD--TIIPEVP 1268
Q + V + C NL+ G EY V V S P I+ E
Sbjct: 21004 QRKGSDQWTHITTVKGLE---CVVRNLTEGEEYTFQVMAVNSAGRSAPRESRPVIVKEQT 21060
Query: 1269 QLTDLSFVDITDSSIGLRWTPLNSSTI--IGYRITVVAAGEGIPI--------FEDFVDS 1318
L +L I + + I +G V +G I FE S
Sbjct: 21061 MLPELDLRGIYQKLVIAKAGDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATS 21120
Query: 1319 SVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTW 1378
++ Y ++ ++ T PP ++F + D + +W
Sbjct: 21121 TILNINECVRSDSGPYPLTARNIVGEVGDVITIQVHDIPGPPTGPIKFDEVSSDFVTFSW 21180
Query: 1379 APPPS---IDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSS---- 1431
PP + + ++N++V + V EL+ + T L G EY V +
Sbjct: 21181 DPPENDGGVPISNYVVEMRQTDSTTWV-ELATTVIRTTYKATRLTTGLEYQFRVKAQNRY 21239
Query: 1432 -VYEQHESTPLRGRQKTGLDSPTGI-DFSDITANSFTVHWIAP----RATITGYRIRHHP 1485
V S + + P G + +T +S T+ W P + I GY +
Sbjct: 21240 GVGPGITSACIVANYPFKVPGPPGTPQVTAVTKDSMTISWHEPLSDGGSPILGYHVERKE 21299
Query: 1486 EHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN-------GREESPLLIGQQSTV 1538
+ + N + LT G Y ++A N + P+L
Sbjct: 21300 RNGILWQTVSKALVPGNIFKSSGLTDGIAYEFRVIAENMAGKSKPSKPSEPMLALDPIDP 21359
Query: 1539 SDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPG----SKSTA 1594
P L + T T + W P T + +Y + P + ++
Sbjct: 21360 PGKPVPLNITRHTVT---LKWAKPEYTGGFKITSYIVEKRDLPNGRWLKANFSNILENEF 21416
Query: 1595 TISGLKPGVDYTITVYAVTGRGD-SPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKW 1653
T+SGL Y V A G SP S +I R +++ P +D I
Sbjct: 21417 TVSGLTEDAAYEFRVIAKNAAGAISPPSEPSDAITCRDDVEAPKIKVDVKFKDTVI---- 21472
Query: 1654 LPSSSPVTGYRVTTTPKNGPGPTK------TKTAGPDQTEMTIEGLQPTV---------E 1698
+R+ P PT + G + E+ I +
Sbjct: 21473 ---LKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDS 21529
Query: 1699 YVVSVYAQNPSGESQPLVQTAVTNIDRP----KGLAFTDVDVDSIKIAWESP---QGQVS 1751
++ A NP G ++ + V +DRP LA T+V + ++W P G
Sbjct: 21530 GAYTLTATNPGGFAKHIFNVKV--LDRPGPPEGPLAVTEVTSEKCVLSWFPPLDDGGAKI 21587
Query: 1752 RYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALH-----DDMESQPLI 1806
+ + + A + + ++ L G+EY V+A++ + +ES+P++
Sbjct: 21588 DHYIVQKRETSRLAWTNVASEVQVTKLKVTKLLKGNEYIFRVMAVNKYGVGEPLESEPVL 21647
Query: 1807 GTQSTAIP-APTDLKFTQVTPTSLSAQWTPPN----VQLTGYRVRVTPKEKTGPMKEINL 1861
P P + + T +T S+ W P+ ++ Y V K +K
Sbjct: 21648 AVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEIINYIVERRDKAGQRWIKCNKK 21707
Query: 1862 APDSSSVVVSGLMVATKYEVSVYA-----LKDTLTSRPAQGVVTTLENVSPPRRARVTDA 1916
VSGL +YE + A + + P T+ PP RV D
Sbjct: 21708 TLTDLRYKVSGLTEGHEYEFRIMAENAAGISAPSPTSPFYKACDTVFKPGPPGNPRVLDT 21767
Query: 1917 TETTITISWRTKT----ETITGFQVD-AVPANGQTPIQRTIKP----DVRSYTITGLQPG 1967
+ ++I+I+W ITG+ V+ A+P + I + P SYTITGL
Sbjct: 21768 SRSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQI---VTPPAGLKATSYTITGLTEN 21824
Query: 1968 TDYKIYLYTLNDNARSSPVVI 1988
+YKI +Y +N P ++
Sbjct: 21825 QEYKIRIYAMNSEGLGEPALV 21845
Score = 106 bits (265), Expect = 2e-22
Identities = 320/1538 (20%), Positives = 543/1538 (35%), Gaps = 226/1538 (14%)
Query: 702 TSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSW----VSASDTVSGFRVEYELS 757
T P S V +T P VT+++ V W +++G+ +E
Sbjct: 18378 TGPPTESKPVIAKTKYDKPGRPDPPEVTKVSKEEMTVVWNPPEYDGGKSITGYFLE---K 18434
Query: 758 EEGDEPQYLDLPSTATS---VNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDA- 813
+E +++ + +A + + +LLP +Y V +E G L + A D
Sbjct: 18435 KEKHSTRWVPVNKSAIPERRMKVQNLLPDHEYQFRVKAENEIGIGEPSLPSRPVVAKDPI 18494
Query: 814 --PPDPTVDQVDDT---SIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANS 864
P PT +V DT SI + W +P API GY + P + +S + +
Sbjct: 18495 EPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAPIIGYVVEMRPKIADASPDEGWKRCNAA 18554
Query: 865 VTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGT------------------PRSDT 906
L V+ T+ +++ENQE V Q G P D
Sbjct: 18555 AQL------VRKEFTVTSLDENQEYEFRVCAQNQVGIGRPAELKEAIKPKEILEPPEIDL 18608
Query: 907 VPSPRDLQFVEV-TDVKV-TIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEV 964
S R L V +++ I+ P VT +V + V GQ + F +
Sbjct: 18609 DASMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVV---RKGQVDLVDTMAFLVI 18665
Query: 965 TGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAP-TNLQFVNETDSTVLVRWTPPR-- 1021
+ + + + V+ E + P ++L+ + T ++ V W PP
Sbjct: 18666 PNSTRDDSGKYSLTLVNPAGEKAVFVNVRVLDTPGPVSDLKVSDVTKTSCHVSWAPPEND 18725
Query: 1022 --AQITGYRLTVGLTRRGQPRQYNVGPSVSK--YPLRNLQPASEYTVSLVAIKGNQESPK 1077
+Q+T Y V + V P V K + + NL P +EY + A+ N+ P
Sbjct: 18726 GGSQVTHY--IVEKREADRKTWSTVTPEVKKTSFHVTNLVPGNEYYFRVTAV--NEYGPG 18781
Query: 1078 ATG-----VFTTLQPGSSIPPYNTEVTETT---IVITWTPAPRIG-FKLG--VRPSQGGE 1126
V + PP EVTE T + W P R G K+ + + E
Sbjct: 18782 VPTDVPKPVLASDPLSEPDPPRKLEVTEMTKNSATLAWLPPLRDGGAKIDGYITSYREEE 18841
Query: 1127 APREVTSDSG-----SIVVSGLTPGVEYVYTI---QVLRDGQERDAPIVNKVVTPLSPPT 1178
P + ++ S+VV+GL G +Y + + + R+A V + L PP
Sbjct: 18842 QPADRWTEYSVVKDLSLVVTGLKEGKKYKFRVAARNAVGVSLPREAEGVYEAKEQLLPPK 18901
Query: 1179 NL-----------------HLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSL 1221
L H+ P T W++ +T + + +
Sbjct: 18902 ILMPEQITIKAGKKLRIEAHVYGKPHP---TCKWKKGEDEVVTSSHLAVHKADSSSILII 18958
Query: 1222 EEVVHADQS--SCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPEVPQLTDLSFVDIT 1279
++V D S T +N S K V + D P P D+S DI
Sbjct: 18959 KDVTRKDSGYYSLTAENSSG----------TDTQKIKVVVMDAPGPPQPPF-DIS--DID 19005
Query: 1280 DSSIGLRW-TPLNS--STIIGYRITV--VAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDY 1334
+ L W PL S I Y + V+ G+ + +S V L PG +Y
Sbjct: 19006 ADACSLSWHIPLEDGGSNITNYIVEKCDVSRGDWVTALASVTKTSC---RVGKLIPGQEY 19062
Query: 1335 DISVITLINGGESAPTTLTQQTAVPP------PTDLRFTNIGPDTMRVTWAPPPSIDLTN 1388
V G S P T + A P P + R T + D + V W P S D +
Sbjct: 19063 IFRVRAENRFGISEPLTSPKMVAQFPFGVPSEPKNARVTKVNKDCIFVAWDRPDS-DGGS 19121
Query: 1389 FLVRYSPVKNEEDVAELSISPSDNAVVLTN-----LLPGTEYVVSVSSVYEQHESTPLRG 1443
++ Y ++ +E + L + +D V T L+ G EY + ++ + S P +
Sbjct: 19122 PIIGYL-IERKERNSLLWVKANDTLVRSTEYPCAGLVEGLEYSFRIYALNKAGSSPPSKP 19180
Query: 1444 RQ----KTGLDSPTGIDFSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPRED 1495
+ + +D P + D+T ++ ++ W P+ + I GY + R +
Sbjct: 19181 TEYVTARMPVDPPGKPEVIDVTKSTVSLIWARPKHDGGSKIIGYFVEACKLPGDKWVRCN 19240
Query: 1496 RVPHS--RNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTV---SDVPRDLEVVAA 1550
PH + T T L +Y +A SP +VP +++ A
Sbjct: 19241 TAPHQIPQEEYTATGLEEKAQYQFRAIARTAVNISPPSEPSDPVTILAENVPPRIDLSVA 19300
Query: 1551 TPTSLLIS------WDAPAVTVRYYRITYGETGGN-SPVQEFTVPGSKSTATIS----GL 1599
+ L + DA +++ + G P + + ++ T+
Sbjct: 19301 MKSLLTVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNR 19360
Query: 1600 KPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLP---- 1655
K DYTIT S + S I + + P+ +++ + + + W P
Sbjct: 19361 KDSGDYTITA-----ENSSGSKSATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLED 19415
Query: 1656 SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPL 1715
S +T Y V + P + P T ++E L EY + A+N G P+
Sbjct: 19416 GGSEITNYIVDKRETSRPNWAQVSATVPI-TSCSVEKLIEGHEYQFRICAENKYGVGDPV 19474
Query: 1716 -VQTAVT-NIDRPKGLA----FTDVDVDSIKIAWESPQGQ----VSRYRVTYSSPEDGIH 1765
+ A+ N P G +++ D + ++W+ P ++ Y + +
Sbjct: 19475 FTEPAIAKNPYDPPGRCDPPVISNITKDHMTVSWKPPADDGGSPITGYLLEKRETQAVNW 19534
Query: 1766 ELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAI------PAPTDL 1819
E T + GL+ G+EY V A++ +P +++ P P
Sbjct: 19535 TKVNRKPIIERTLKATGLQEGTEYEFRVTAINKAGPGKPSDASKAAYARDPQYPPGPPAF 19594
Query: 1820 -KFTQVTPTSLSAQWTPPNVQ----LTGYRVRVTPKEKTGPMKEINLAPD--SSSVVVSG 1872
K T +S+S W P + GY V V + ++ NL + + V+G
Sbjct: 19595 PKVYDTTRSSVSLSWGKPAYDGGSPIIGYLVEVKRADSDNWVR-CNLPQNLQKTRFEVTG 19653
Query: 1873 LMVATKYEVSVYALKDTLTSRPAQ--GVVTTLENVSPPRRARVTDATETTITISWRTKTE 1930
LM T+Y+ VYA+ S P+ + + PP D +T I + T
Sbjct: 19654 LMEDTQYQFRVYAVNKIGYSDPSDVPDKHYPKDILIPPEGELDADLRKTLILRAGVTMRL 19713
Query: 1931 TITGFQVDAVPANGQTPIQRT-IKPDVRSYTITGLQ-PGTDYKIYLYTLNDN-------- 1980
VP G+ P + T KP+V GL TD+ +L N N
Sbjct: 19714 --------YVPVKGRPPPKITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKYI 19765
Query: 1981 --------ARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPP----RARITGYIIKY 2028
+ +V+ P N+ + +S V+W+PP + I Y+++
Sbjct: 19766 LTLENSCGKKEYTIVVKVLDTPGPPVNVTVKEISKDSAYVTWEPPIIDGGSPIINYVVQK 19825
Query: 2029 EKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIA 2066
V T + LE G Y V A
Sbjct: 19826 RDAERKSWSTV-TTECSKTSFRVANLEEGKSYFFRVFA 19862
Score = 102 bits (255), Expect = 4e-21
Identities = 274/1373 (19%), Positives = 474/1373 (34%), Gaps = 187/1373 (13%)
Query: 766 LDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDT 825
+DL T + IP+ ++ ++ GE+++ ++ P D V V T
Sbjct: 18654 VDLVDTMAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFVNVRVLDTPGPVSDLKVSDVTKT 18713
Query: 826 SIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETAN-SVTLSDLQPGVQYNITI 880
S V W+ P+ + +T Y IV + + PE S +++L PG +Y +
Sbjct: 18714 SCHVSWAPPENDGGSQVTHY-IVEKREADRKTWSTVTPEVKKTSFHVTNLVPGNEYYFRV 18772
Query: 881 YAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTG 936
AV E P + + + PR L+ E+T T+ W PP + + G
Sbjct: 18773 TAVNEYGPGVPTDVPKPVLASDPLSEPDPPRKLEVTEMTKNSATLAWLPPLRDGGAKIDG 18832
Query: 937 YRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTK 996
Y P + + ++ VTGL G Y F+V A+
Sbjct: 18833 YITSYREEEQPADRWTEYSVVKDLSLVVTGLKEGKKYKFRV------------AARNAVG 18880
Query: 997 LDAPTNLQFVNETDSTVLVRWTPPR----AQIT---GYRLTVGLTRRGQPR--------- 1040
+ P + V E +L PP+ QIT G +L + G+P
Sbjct: 18881 VSLPREAEGVYEAKEQLL----PPKILMPEQITIKAGKKLRIEAHVYGKPHPTCKWKKGE 18936
Query: 1041 ---------QYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSI 1091
+ S S ++++ SL A + + V PG
Sbjct: 18937 DEVVTSSHLAVHKADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPGPPQ 18996
Query: 1092 PPYN-TEVTETTIVITW-TPAPRIGFKL------GVRPSQGGEAPREVTSDSGSIVVSGL 1143
PP++ +++ ++W P G + S+G + S V L
Sbjct: 18997 PPFDISDIDADACSLSWHIPLEDGGSNITNYIVEKCDVSRGDWVTALASVTKTSCRVGKL 19056
Query: 1144 TPGVEYVYTIQVLRDGQERDAPIVNKVV------TPLSPPTNLHLEANPDTGVLTVSWER 1197
PG EY++ ++ + K+V P P + N D + V+W+R
Sbjct: 19057 IPGQEYIFRVRAENRFGISEPLTSPKMVAQFPFGVPSEPKNARVTKVNKD--CIFVAWDR 19114
Query: 1198 STT---PDITGYRITTTPTNGQQG-NSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDD 1253
+ I GY I N + + +V + + C L GLEY+ +Y +
Sbjct: 19115 PDSDGGSPIIGYLIERKERNSLLWVKANDTLVRSTEYPCA--GLVEGLEYSFRIYALNKA 19172
Query: 1254 KESVPISDTIIPEVPQLTD----LSFVDITDSSIGLRWTPL---NSSTIIGYRITVV--- 1303
S P T D +D+T S++ L W S IIGY +
Sbjct: 19173 GSSPPSKPTEYVTARMPVDPPGKPEVIDVTKSTVSLIWARPKHDGGSKIIGYFVEACKLP 19232
Query: 1304 --------AAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVI--TLIN----GGESAP 1349
A IP E YT TGLE Y I T +N S P
Sbjct: 19233 GDKWVRCNTAPHQIPQEE---------YTATGLEEKAQYQFRAIARTAVNISPPSEPSDP 19283
Query: 1350 TTLTQQTAVPPPTDLRF-----------TNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKN 1398
T+ + VPP DL TN+ D V P P++ P +
Sbjct: 19284 VTILAEN-VPPRIDLSVAMKSLLTVKAGTNVCLDA-TVFGKPMPTVSWKKDGTLLKPAEG 19341
Query: 1399 EEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHEST-PLRGRQKTGLDSPTGIDF 1457
+ + ++ + + N +Y ++ + +T L+ K G P +
Sbjct: 19342 IKMAMQRNLCTLE--LFSVNRKDSGDYTITAENSSGSKSATIKLKVLDKPG--PPASVKI 19397
Query: 1458 SDITANSFTVHWIAP----RATITGYRIRHHPEHFSGRPREDRVPHS--RNSITLTNLTP 1511
+ + ++ + W P + IT Y + + + RP +V + S ++ L
Sbjct: 19398 NKMYSDRAMLSWEPPLEDGGSEITNYIV---DKRETSRPNWAQVSATVPITSCSVEKLIE 19454
Query: 1512 GTEYVVSIVALNGREESPLLIGQQSTVS---DVPR--DLEVVA-ATPTSLLISWDAPA-- 1563
G EY I A N + + + D P D V++ T + +SW PA
Sbjct: 19455 GHEYQFRICAENKYGVGDPVFTEPAIAKNPYDPPGRCDPPVISNITKDHMTVSWKPPADD 19514
Query: 1564 --VTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRG---DS 1618
+ Y + ET + + P + T +GL+ G +Y V A+ G S
Sbjct: 19515 GGSPITGYLLEKRETQAVNWTKVNRKPIIERTLKATGLQEGTEYEFRVTAINKAGPGKPS 19574
Query: 1619 PASSKPISINYRTEIDKPSQMQVTDVQDNSISVKW----LPSSSPVTGYRVTTTPKNGPG 1674
AS + + + P+ +V D +S+S+ W SP+ GY V +
Sbjct: 19575 DASKAAYARDPQYPPGPPAFPKVYDTTRSSVSLSWGKPAYDGGSPIIGYLVEVKRADSDN 19634
Query: 1675 PTKTK-TAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFT- 1732
+ +T + GL +Y VYA N G S P + V + PK +
Sbjct: 19635 WVRCNLPQNLQKTRFEVTGLMEDTQYQFRVYAVNKIGYSDP---SDVPDKHYPKDILIPP 19691
Query: 1733 --DVDVDSIKIAWESPQGQVSRY---------RVTYSSPEDGIHELFPAPDGEED----- 1776
++D D K + Y ++T+S P + + D
Sbjct: 19692 EGELDADLRKTLILRAGVTMRLYVPVKGRPPPKITWSKPNVNLRDRIGLDIKSTDFDTFL 19751
Query: 1777 TAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPP 1836
E +Y +++ E ++ T P P ++ +++ S W PP
Sbjct: 19752 RCENVNKYDAGKYILTLENSCGKKEYTIVVKVLDTPGP-PVNVTVKEISKDSAYVTWEPP 19810
Query: 1837 NVQ----LTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTS 1892
+ + Y V+ E+ + +S V+ L Y V+A +
Sbjct: 19811 IIDGGSPIINYVVQKRDAERKS-WSTVTTECSKTSFRVANLEEGKSYFFRVFAENEYGIG 19869
Query: 1893 RPAQ--GVVTTLENVSPPRRARVTDATETTITISWRTK----TETITGFQVDAVPANGQT 1946
P + V + P +V ++++ +I W+ I G+ VD + +
Sbjct: 19870 DPGETRDAVKASQTPGPVVDLKVRSVSKSSCSIGWKKPHSDGGSRIIGYVVDFLTEENKW 19929
Query: 1947 PIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSP--VVIDASTAIDAP 1997
QR +K Y+ L G +Y + N+N +P + + A + AP
Sbjct: 19930 --QRVMKSLSLQYSAKDLTEGKEYTFRVSAENENGEGTPSEITVVARDDVVAP 19980
Score = 102 bits (255), Expect = 4e-21
Identities = 306/1554 (19%), Positives = 528/1554 (33%), Gaps = 201/1554 (12%)
Query: 610 GPVEVFITETPSQPNSHPIQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSY 666
GP E + T + WN P ++IS YI+ R + + W + + +Y
Sbjct: 24803 GPPEGPLKVTGVTAEKCYLAWNPPLQDGGANISHYIIEKRETSRLS-WTQVSTEVQALNY 24861
Query: 667 TIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSE 726
+ L PG Y +++++ +YG E P+ S VT P ++
Sbjct: 24862 KVTKLLPGNEYIFRVMAVNKYGIGE-------------PLESGPVTACNPYKPPGPPSTP 24908
Query: 727 SVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDE-----PQYLDLPSTATSVNIPDLL 781
V+ IT S VV+W D G +E + E+ D+ + T + + L
Sbjct: 24909 EVSAITKDSMVVTWARPVDD-GGTEIEGYILEKRDKEGVRWTKCNKKTLTDLRLRVTGLT 24967
Query: 782 PGRKY-----IVNVYQISEDGEQSLILSTSQTTAPDAPP-DPTVDQVDDTSIVVRWSRP- 834
G Y N + E E S+ P PP +P V +S+ + WS+P
Sbjct: 24968 EGHSYEFRVAAENAAGVGEPSEPSVFYRACDALYPPGPPSNPKVTDTSRSSVSLAWSKPI 25027
Query: 835 ---QAPITGYRIVYSPSVEGSSTELNLPE--TANSVTLSDLQPGVQYNITIYAVEENQES 889
AP+ GY + + T P T++ L+ +YN I A+
Sbjct: 25028 YDGGAPVKGYVVEVKEAAADEWTTCTPPTGLQGKQFTVTKLKENTEYNFRICAINSEGVG 25087
Query: 890 TPVVIQQETTGTPRSD--TVPSPRDLQFVEVTDVKVTI-----MWTPPESAVTGYRVDVI 942
P + R + + DL+ V V T+ + PE V + + I
Sbjct: 25088 EPATLPGSVVAQERIEPPEIELDADLRKVVVLRASATLRLFVTIKGRPEPEVKWEKAEGI 25147
Query: 943 PVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTN 1002
+ + + VT G Y + G ++ + + AP N
Sbjct: 25148 LTD-RAQIEVTSSFTMLVIDNVTRFDSG--RYNLTLENNSGSKTAFVNVRVLDSPSAPVN 25204
Query: 1003 LQFVNETDSTVLVRWTPP----RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQP 1058
L +V + W PP A+IT Y + T R + + + + NLQ
Sbjct: 25205 LTIREVKKDSVTLSWEPPLIDGGAKITNYIVEKRETTRKAYATITNNCTKTTFRIENLQE 25264
Query: 1059 ASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYN------TEVTETTIVITW-TPAP 1111
Y ++A + E TT S PP +VT T I W P
Sbjct: 25265 GCSYYFRVLA---SNEYGIGLPAETTEPVKVSEPPLPPGRVTLVDVTRNTATIKWEKPES 25321
Query: 1112 RIGFKLG----VRPSQGGEAPREVTS-DSGSIVVSGLTPGVEYVYTIQVLR-----DGQE 1161
G K+ ++G E T + +SGLT G EYV+ + + D ++
Sbjct: 25322 DGGSKITGYVVEMQTKGSEKWSTCTQVKTLEATISGLTAGEEYVFRVAAVNEKGRSDPRQ 25381
Query: 1162 RDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDIT-GYRITTTPTNGQQGNS 1220
P++ + + + P L V D+ R T + G +
Sbjct: 25382 LGVPVIARDI-EIKPSVELPFH------TFNVKAREQLKIDVPFKGRPQATVNWRKDGQT 25434
Query: 1221 LEEVVHADQSS---CTFDNLSPGLEYNVSVY--TVKDDKESVPISDTII------PEVPQ 1269
L+E + SS T ++ + +V Y V + S+ + TII P P
Sbjct: 25435 LKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSNSAGSITVPITIIVLDRPGPPGPI 25494
Query: 1270 LTDLSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIFEDFVDSSVGYYT--VTG 1327
D +++ SI + W P +V E V +V + +
Sbjct: 25495 RID----EVSCDSITISWNPPEYDGGCQISNYIVEKKETTSTTWHIVSQAVARTSIKIVR 25550
Query: 1328 LEPGIDYDISVITLINGGESAPTTLTQQTA------VPPPTDLRFTNIGPDTMRVTWAPP 1381
L G +Y V G+S+ + + A PP + + TM VTW P
Sbjct: 25551 LTTGSEYQFRVCAENRYGKSSYSESSAVVAEYPFSPPGPPGTPKVVHATKSTMLVTWQVP 25610
Query: 1382 PSIDLTNFLVRYSPVKNEEDV---AELSISPSDNAVVLTNLLPGTEY--------VVSVS 1430
+ + + + K + I +D + ++ L G Y + +
Sbjct: 25611 VNDGGSRVIGYHLEYKERSSILWSKANKILIADTQMKVSGLDEGLMYEYRVYAENIAGIG 25670
Query: 1431 SVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPR----ATITGYRIRHHPE 1486
+ E P R D P + ++IT S ++ W P A ITGY + E
Sbjct: 25671 KCSKSCEPVPAR----DPCDPPGQPEVTNITRKSVSLKWSKPHYDGGAKITGYIVERR-E 25725
Query: 1487 HFSGRPREDRVPHSRNS-ITLTNLTPGTEYVVSIVALNGREE--------SPLLIGQQST 1537
GR + + + + +T LT Y + A N + P+++
Sbjct: 25726 LPDGRWLKCNYTNIQETYFEVTELTEDQRYEFRVFARNAADSVSEPSESTGPIIVKDDVE 25785
Query: 1538 VSDVPRDLE----VVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKST 1593
V D++ +V L I+ D + I++ + G + T S
Sbjct: 25786 PPRVMMDVKFRDVIVVKAGEVLKINADIAGRPLPV--ISWAKDGIEIEERARTEIISTDN 25843
Query: 1594 ATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKP----SQMQVTDVQDNSI 1649
T+ +K + Y +T + + A ++ +++N + +DKP +++ +
Sbjct: 25844 HTLLTVKDCIRRDTGQYVLTLK--NVAGTRSVAVNCKV-LDKPGPPAGPLEINGLTAEKC 25900
Query: 1650 SVKW---LPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQ 1706
S+ W Y + + T + L EY+ V
Sbjct: 25901 SLSWGRPQEDGGADIDYYIVEKRETSHLAWTICEGELQMTSCKVTKLLKGNEYIFRVTGV 25960
Query: 1707 NPSGESQPLVQTAVTNID------RPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSP 1760
N G +PL A+ +D P L T V +S+ + W P+ Y
Sbjct: 25961 NKYGVGEPLESVAIKALDPFTVPSPPTSLEITSVTKESMTLCWSRPESDGGSEISGYIIE 26020
Query: 1761 EDGIHELFPAPDGEEDTAELQ----GLRPGSEYTVSVVA-----LHDDMESQPLIGTQST 1811
+ L ++ +L+ GLR G EY V A L E+ PLI +
Sbjct: 26021 RREKNSLRWVRVNKKPVYDLRVKSTGLREGCEYEYRVYAENAAGLSLPSETSPLIRAEDP 26080
Query: 1812 A-IPA-PTDLKFTQVTPTSLSAQWTPP----NVQLTGYRVRVTPKEKTGPMKEINLAPDS 1865
+P+ P+ K T+++ W P +TGY V + T I +
Sbjct: 26081 VFLPSPPSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEYKKSDDTDWKTSIQ-SLRG 26139
Query: 1866 SSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENV----------SPPRRARVTD 1915
+ +SGL +Y V ++ S P+ + S R+ +
Sbjct: 26140 TEYTISGLTTGAEYVFRVKSVNKVGASDPSDSSDPQIAKEREEEPLFDIDSEMRKTLIVK 26199
Query: 1916 A-TETTITISWRTK-----------TETITGFQVDAVPANGQTPIQRTIKPDVRSYTITG 1963
A T+T+ +R + T+ T VD + I+ + D YT+T
Sbjct: 26200 AGASFTMTVPFRGRPVPNVLWSKPDTDLRTRAYVDTTDSRTSLTIENANRNDSGKYTLT- 26258
Query: 1964 LQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPP 2017
+Q +A S +V+ P+N+ T S ++SW P
Sbjct: 26259 IQNVL-----------SAASLTLVVKVLDTPGPPTNITVQDVTKESAVLSWDVP 26301
Score = 102 bits (255), Expect = 4e-21
Identities = 136/661 (20%), Positives = 242/661 (36%), Gaps = 91/661 (13%)
Query: 1514 EYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVT----VRYY 1569
+Y + +G++ + +L+ T P ++V + S+ I+W+ P + V Y
Sbjct: 29514 KYTIEAENQSGKKSATVLVKVYDTPGPCP-SVKVKEVSRDSVTITWEIPTIDGGAPVNNY 29572
Query: 1570 RITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYA--VTGRGDSPASSKPISI 1627
+ E + + T SK+ ISGL G Y V + G G+ +S + +
Sbjct: 29573 IVEKREAAMRA-FKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYGIGEPCETSDAVLV 29631
Query: 1628 NYRTEIDKPSQMQVTDVQDNSISVKW----LPSSSPVTGYRVTTTPKNGPGPTKTKTAGP 1683
+ + P++++V DV +++++ W S +TGY + K T P
Sbjct: 29632 SEVPLV--PAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGTERWMKVVTLKP 29689
Query: 1684 DQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAW 1743
E T+ L +Y+ + AQN G S+P + + L D+ K
Sbjct: 29690 TVLEHTVTSLNEGEQYLFRIRAQNEKGVSEPRETVTAVTVQDLRVLPTIDLSTMPQKTI- 29748
Query: 1744 ESPQGQVSRYRVTYSSPEDGIHELFPAPDG--EEDTAELQGLRPGSEYTVSVVALHDD-- 1799
P G+ + + F A E + ++ ++ T+ + D
Sbjct: 29749 HVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAKLTIRETTIRDTGE 29808
Query: 1800 --MESQPLIGTQSTAI---------PAPTDLKFTQVTPTSLSAQWTPPNVQ----LTGYR 1844
+E + + GT S I P +K ++ TS++ W PP + L+GY
Sbjct: 29809 YTLELKNVTGTTSETIKVIILDKPGPPTGPIKIDEIDATSITISWEPPELDGGAPLSGYV 29868
Query: 1845 VRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLEN 1904
V + G + P S SV S E + Y + T+R G E
Sbjct: 29869 VEQRDAHRPGWL------PVSESVTRSTFKFTRLTEGNEYVFRVAATNRFGIGSYLQSEV 29922
Query: 1905 VS---------PPRRARVTDATETTITISWRTKTET----ITGFQVDAVPANGQTPIQRT 1951
+ PP ++ D + +T++W + +TG+ V+ ++
Sbjct: 29923 IECRSSIRIPGPPETLQIFDVSRDGMTLTWYPPEDDGGSQVTGYIVERKEVRADRWVRVN 29982
Query: 1952 IKP-DVRSYTITGLQPGTDYKIYLYTLNDNARSSP-------VVIDASTAIDAPSNLRFL 2003
P + Y TGL G +Y+ + +N P V +D P N R
Sbjct: 29983 KVPVTMTRYRSTGLTEGLEYEHRVTAINARGSGKPSRPSKPIVAMDPIAPPGKPQNPRVT 30042
Query: 2004 ATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTE 2059
TT S+ ++W P +++TGY+I+ +K + E T+T L G E
Sbjct: 30043 DTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTKCNTTPTKIREYTLTHLPQGAE 30102
Query: 2060 YTIYVIALKNNQKSEPLIGRKKTDELPQLVTLPHPNLHGPEILDVPSTVQKTPFVTHPGY 2119
Y V+A EP +VP TV+ T + +P Y
Sbjct: 30103 YRFRVLACNAGGPGEP--------------------------AEVPGTVKVTEMLEYPDY 30136
Query: 2120 D 2120
+
Sbjct: 30137 E 30137
Score = 100 bits (248), Expect = 2e-20
Identities = 162/726 (22%), Positives = 275/726 (37%), Gaps = 92/726 (12%)
Query: 1268 PQLTDLSFVDITDSSIGLRWTPLN---SSTIIGYRITVVAAGEG--IPIFEDFVDSSVGY 1322
P + +I +SI + W P + + GY + A +P+ E S+
Sbjct: 29834 PPTGPIKIDEIDATSITISWEPPELDGGAPLSGYVVEQRDAHRPGWLPVSESVTRST--- 29890
Query: 1323 YTVTGLEPGIDYDISVITLINGG-----ESAPTTLTQQTAVP-PPTDLRFTNIGPDTMRV 1376
+ T L G +Y V G +S +P PP L+ ++ D M +
Sbjct: 29891 FKFTRLTEGNEYVFRVAATNRFGIGSYLQSEVIECRSSIRIPGPPETLQIFDVSRDGMTL 29950
Query: 1377 TWAPPPS---IDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVY 1433
TW PP +T ++V V+ + V + + T L G EY V+++
Sbjct: 29951 TWYPPEDDGGSQVTGYIVERKEVRADRWVRVNKVPVTMTRYRSTGLTEGLEYEHRVTAIN 30010
Query: 1434 EQHESTPLR-GRQKTGLD------SPTGIDFSDITANSFTVHWIAPR----ATITGYRIR 1482
+ P R + +D P +D T S ++ W P + +TGY I
Sbjct: 30011 ARGSGKPSRPSKPIVAMDPIAPPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIE 30070
Query: 1483 HHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVP 1542
+ + P TLT+L G EY ++A N G ++VP
Sbjct: 30071 MQKVDQHEWTKCNTTPTKIREYTLTHLPQGAEYRFRVLACNA--------GGPGEPAEVP 30122
Query: 1543 RDLEVVAAT--PTSLLISWDAPAVTVRY---YRITYGETGGNSPVQEFTVPGSKSTATIS 1597
++V P L + VR R+T G P+ ++T G + + +
Sbjct: 30123 GTVKVTEMLEYPDYELDERYQEGIFVRQGGVIRLTIPIKGKPFPICKWTKEG-QDISKRA 30181
Query: 1598 GLKPGVDYTITVYAVTGRGDS---------PASSKPISINYRTEIDKPSQ----MQVTDV 1644
+ +T V RGDS K + I R I P+ ++ D+
Sbjct: 30182 MIATSETHTELVIKEADRGDSGTYDLVLENKCGKKAVYIKVRV-IGSPNSPEGPLEYDDI 30240
Query: 1645 QDNSISVKWLPSS----SPVTGYRVTT--TPKNGPGPTKTKTAGPDQTEMTIEGLQPTVE 1698
Q S+ V W P + + + GY + PK ++ G T + ++GL+ VE
Sbjct: 30241 QVRSVRVSWRPPADDGGADILGYILERREVPKAAWYTIDSRVRG---TSLVVKGLKENVE 30297
Query: 1699 YVVSVYAQNPSGESQPLVQ----TAVTNIDRPKGLA----FTDVDVDSIKIAWESPQGQ- 1749
Y V A+N G S+PL T T ++ P+ + DV S+ ++W P+
Sbjct: 30298 YHFRVSAENQFGISKPLKSEEPVTPKTPLNPPEPPSNPPEVLDVTKSSVSLSWSRPKDDG 30357
Query: 1750 VSRYRVTYSSPEDGIHELFPAPDGEEDTAEL---QGLRPGSEYTVSVVALHD------DM 1800
SR Y ++ + + + + T + GL P +EY ++A +D
Sbjct: 30358 GSRVTGYYIERKETSTDKWVRHNKTQITTTMYTVTGLVPDAEYQFRIIAQNDVGLSETSP 30417
Query: 1801 ESQPLIGTQSTAIPA-PTDLKFTQVTPTSLSAQWTPPNV----QLTGYRVRVTPKEKTGP 1855
S+P++ P+ P +L+ ++ S++ QW P ++ GY V +
Sbjct: 30418 ASEPVVCKDPFDKPSQPGELEILSISKDSVTLQWEKPECDGGKEILGYWVEYRQSGDSAW 30477
Query: 1856 MKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRP---AQGVVTTL-ENVSPPRRA 1911
K + GL+ AT+YE V+A +T SRP A + T L +P R
Sbjct: 30478 KKSNKERIKDKQFTIGGLLEATEYEFRVFAENETGLSRPRRTAMSIKTKLTSGEAPGIRK 30537
Query: 1912 RVTDAT 1917
+ D T
Sbjct: 30538 EMKDVT 30543
Score = 99.8 bits (247), Expect = 3e-20
Identities = 244/1107 (22%), Positives = 422/1107 (38%), Gaps = 171/1107 (15%)
Query: 1092 PPYNTEVTET---TIVITWT-PAPRIGFKLGVRPSQGGEAPREV------TSDSGSIVVS 1141
P N EVTET + + W P G K+ + + R+ ++S V+
Sbjct: 13092 PVRNLEVTETFDGEVSLAWEEPLTDGGSKIIGYVVERRDIKRKTWVLATDRAESCEFTVT 13151
Query: 1142 GLTPG-VEYVYTIQVLR-----DGQERDAPIV--NKVVTPLSPPTNLHLEANPDTGVLTV 1193
GL G VEY++ + + E D P+ +K P PP N+ + GV ++
Sbjct: 13152 GLQKGGVEYLFRVSARNRVGTGEPVETDNPVEARSKYDVP-GPPLNVTITDVNRFGV-SL 13209
Query: 1194 SWERSTTP---DITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYT- 1249
+WE +IT Y I + ++ V A+ S T ++ G EY+ V
Sbjct: 13210 TWEPPEYDGGAEITNYVIELRDKTSIRWDTAM-TVRAEDLSATVTDVVEGQEYSFRVRAQ 13268
Query: 1250 --VKDDKES-----VPISDTIIPEVPQLTDLSFVDITDSSIGLRWTPL---NSSTIIGYR 1299
+ K S V ++D I P + +L+ D T SS+ L+W P S I+GY
Sbjct: 13269 NRIGVGKPSAATPFVKVADPIERPSPPV-NLTSSDQTQSSVQLKWEPPLKDGGSPILGYI 13327
Query: 1300 ITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLT------ 1353
I G+ I + Y VTGLE G Y V G S P+ +
Sbjct: 13328 IERCEEGKDNWIRCNMKLVPELTYKVTGLEKGNKYLYRVSAENKAGVSDPSEILGPLTAD 13387
Query: 1354 ----------------QQTAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVK 1397
+ VP P + + G TW + T V+ +K
Sbjct: 13388 DAFVEPTMDLSAFKDGLEVIVPNPITILVPSTGYPRPTATWCFGDKVLETGDRVK---MK 13444
Query: 1398 NEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHE-STPLRGRQKTGLDSPTGID 1456
AEL ISPS+ + L V ++S + + + P +P +
Sbjct: 13445 TLSAYAELVISPSERSDKGIYTLKLENRVKTISGEIDVNVIARP---------SAPKELK 13495
Query: 1457 FSDITANSFTVHWIAP----RATITGYRIRHHPEHFSGRPREDRVPHSRNSI--TLTNLT 1510
F DIT +S + W P + +TGY + + R +V + T+ +L
Sbjct: 13496 FGDITKDSVHLTWEPPDDDGGSPLTGYVVE---KREVSRKTWTKVMDFVTDLEFTVPDLV 13552
Query: 1511 PGTEYVVSIVALN-------GREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAP- 1562
G EY+ + A N + P+ + +TV D P +++ T S+ ++WD P
Sbjct: 13553 QGKEYLFKVCARNKCGPGEPAYVDEPVNMSTPATVPDPPENVKWRDRTANSIFLTWDPPK 13612
Query: 1563 ---AVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSP 1619
++ Y + G + V P +++ ++GL+ G Y V A+ +G
Sbjct: 13613 NDGGSRIKGYIVERCPRGSDKWV-ACGEPVAETKMEVTGLEEGKWYAYRVKALNRQG--- 13668
Query: 1620 ASSKPISINYRTEIDKPS-QMQVTDVQDNS---ISVKWLPSSSPVTGYRV----TTTPKN 1671
+SKP +P+ ++Q D Q+ + VK L + G ++ T T K
Sbjct: 13669 -ASKP---------SRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKP 13718
Query: 1672 GPGPTKTKT--AGPDQTEMTIEGL--QPTVEYVVS---------VYAQNPSGESQPLVQT 1718
P T TK +TIE + + TV V S + A N G + +V+
Sbjct: 13719 EPKITWTKADMILKQDKRITIENVPKKSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEV 13778
Query: 1719 AVTNIDR---PKGLAFTDVDVDSIKIAWESPQ----GQVSRYRVTYSSPEDGI-HELFPA 1770
V +D+ P TDV +S + W P+ +++ Y V + + + H+L +
Sbjct: 13779 NV--LDKPGPPAAFDITDVTNESCLLTWNPPRDDGGSKITNYVVERRATDSEVWHKL--S 13834
Query: 1771 PDGEEDTAELQGLRPGSEYTVSVVA-----LHDDMESQPLIGTQSTAIPA-PTDLKFTQV 1824
++ + L P EY V A + + +++ P+ P PT L+ + +
Sbjct: 13835 STVKDTNFKATKLIPNKEYIFRVAAENMYGVGEPVQASPITAKYQFDPPGPPTRLEPSDI 13894
Query: 1825 TPTSLSAQWTPPN----VQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYE 1880
T +++ W P+ +TGY V + ++ + ++ V GL KY
Sbjct: 13895 TKDAVTLTWCEPDDDGGSPITGYWVERLDPDTDKWVRCNKMPVKDTTYRVKGLTNKKKYR 13954
Query: 1881 VSVYALKDTLTSRPAQG-----VVTTLENVSPPRRARVTDATETTITISWRTKTE----- 1930
V A +P++ + ++ PP + V D +T++ ++W TK E
Sbjct: 13955 FRVLAENLAGPGKPSKSTEPILIKDPIDPPWPPGKPTVKDVGKTSVRLNW-TKPEHDGGA 14013
Query: 1931 TITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPV---- 1986
I + ++ + ++ + + GL G +Y + +N S P
Sbjct: 14014 KIESYVIEMLKTGTDEWVRVAEGVPTTQHLLPGLMEGQEYSFRVRAVNKAGESEPSEPSD 14073
Query: 1987 VIDASTAIDAPSNLRFLAT---TPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREVV 2039
+ + PS R+L T N+ + W P + IT YI++ + V
Sbjct: 14074 PVLCREKLYPPSPPRWLEVINITKNTADLKWTVPEKDGGSPITNYIVEKRDVRRKGWQTV 14133
Query: 2040 PRPRPGVTEATITGLEPGTEYTIYVIA 2066
T+ T+T L G+ Y V A
Sbjct: 14134 DTTVKD-TKCTVTPLTEGSLYVFRVAA 14159
Score = 99.8 bits (247), Expect = 3e-20
Identities = 292/1340 (21%), Positives = 474/1340 (35%), Gaps = 235/1340 (17%)
Query: 908 PSP-RDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTG 966
P P R+L+ V+V+ + T+ W PPE G + N E + + +T++ T
Sbjct: 18297 PGPVRNLKIVDVSSDRCTVCWDPPEDD-GGCEIQ----NYILEKCETKRMVWSTYS-ATV 18350
Query: 967 LSPGVT---------YYFKVFA-----VSHGRESKPLTAQQTTKLDA-----PTNLQFVN 1007
L+PG T Y F+V A ESKP+ A+ TK D P + V+
Sbjct: 18351 LTPGTTVTRLIEGNEYIFRVRAENKIGTGPPTESKPVIAK--TKYDKPGRPDPPEVTKVS 18408
Query: 1008 ETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSV---SKYPLRNLQPAS 1060
+ + TV+ W PP ITGY L + R V S + ++NL P
Sbjct: 18409 KEEMTVV--WNPPEYDGGKSITGYFLE--KKEKHSTRWVPVNKSAIPERRMKVQNLLPDH 18464
Query: 1061 EYTVSLVAIK----GNQESPKATGVF-TTLQPGSSIPPYNTEVTETT---IVITWTP--- 1109
EY + A G P V ++P PP N V +TT I + W
Sbjct: 18465 EYQFRVKAENEIGIGEPSLPSRPVVAKDPIEPPG--PPTNFRVVDTTKHSITLGWGKPVY 18522
Query: 1110 ---APRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPI 1166
AP IG+ + +RP +P D G + V +T+ L + QE + +
Sbjct: 18523 DGGAPIIGYVVEMRPKIADASP-----DEGWKRCNAAAQLVRKEFTVTSLDENQEYEFRV 18577
Query: 1167 VNKVVTPLSPPTNLHLEANP-----------DTGVLTVSWERSTTPD--ITGYRITTTPT 1213
+ + P L P D + + R+ P R P
Sbjct: 18578 CAQNQVGIGRPAELKEAIKPKEILEPPEIDLDASMRKLVIVRAGCPIRLFAIVRGRPAPK 18637
Query: 1214 NGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDD-------------KESVPIS 1260
+ ++ VV Q +L + + V + +DD +++V ++
Sbjct: 18638 VTWRKVGIDNVVRKGQV-----DLVDTMAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFVN 18692
Query: 1261 DTIIPEVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGYRIT--VVAAGEGIPIFEDFVDS 1318
++ ++DL D+T +S + W P + G ++T +V E V
Sbjct: 18693 VRVLDTPGPVSDLKVSDVTKTSCHVSWAPPENDG--GSQVTHYIVEKREADRKTWSTVTP 18750
Query: 1319 SV--GYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAV-------PPPTDLRFTNI 1369
V + VT L PG +Y V + G PT + + PP L T +
Sbjct: 18751 EVKKTSFHVTNLVPGNEYYFRVTAVNEYGPGVPTDVPKPVLASDPLSEPDPPRKLEVTEM 18810
Query: 1370 GPDTMRVTWAPP---PSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYV 1426
++ + W PP + ++ Y + D D ++V+T L G +Y
Sbjct: 18811 TKNSATLAWLPPLRDGGAKIDGYITSYREEEQPADRWTEYSVVKDLSLVVTGLKEGKKYK 18870
Query: 1427 VSVSSVYEQHESTPLRG----RQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIR 1482
V++ S P K L P + IT + G ++R
Sbjct: 18871 FRVAARNAVGVSLPREAEGVYEAKEQLLPPKILMPEQITIKA-------------GKKLR 18917
Query: 1483 HHPEHFSGRPR--------EDRV----------PHSRNSITLTNLTPGTEYVVSIVALNG 1524
H G+P ED V S + + + ++T S+ A N
Sbjct: 18918 IE-AHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGYYSLTAENS 18976
Query: 1525 ----REESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAP----AVTVRYYRITYGET 1576
++ +++ P D+ + A SL SW P + Y + +
Sbjct: 18977 SGTDTQKIKVVVMDAPGPPQPPFDISDIDADACSL--SWHIPLEDGGSNITNYIVEKCDV 19034
Query: 1577 GGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDS-PASSKPISINYRTEI-D 1634
V +K++ + L PG +Y V A G S P +S + + +
Sbjct: 19035 SRGDWVTAL-ASVTKTSCRVGKLIPGQEYIFRVRAENRFGISEPLTSPKMVAQFPFGVPS 19093
Query: 1635 KPSQMQVTDVQDNSISVKW-LPSS---SPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTI 1690
+P +VT V + I V W P S SP+ GY + +N K TE
Sbjct: 19094 EPKNARVTKVNKDCIFVAWDRPDSDGGSPIIGYLIERKERNSLLWVKANDTLVRSTEYPC 19153
Query: 1691 EGLQPTVEYVVSVYAQNPSGESQPL----VQTAVTNIDRPKGLAFTDVDVDSIKIAWESP 1746
GL +EY +YA N +G S P TA +D P DV ++ + W P
Sbjct: 19154 AGLVEGLEYSFRIYALNKAGSSPPSKPTEYVTARMPVDPPGKPEVIDVTKSTVSLIWARP 19213
Query: 1747 QGQVSRYRVTY-----SSPEDGIHELFPAP---DGEEDTAELQGLRPGSEYTVSVVALHD 1798
+ + Y P D AP EE TA GL ++Y +A
Sbjct: 19214 KHDGGSKIIGYFVEACKLPGDKWVRCNTAPHQIPQEEYTA--TGLEEKAQYQFRAIARTA 19271
Query: 1799 DMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLT-GYRVRVTPKEKTG--- 1854
S P P+D P ++ A+ PP + L+ + +T K T
Sbjct: 19272 VNISPP---------SEPSD-------PVTILAENVPPRIDLSVAMKSLLTVKAGTNVCL 19315
Query: 1855 -------PMKEINLAPDSSSV-VVSGLMVATKYEVSVYAL-----KD----TLTSRPAQG 1897
PM ++ D + + G+ +A + + L KD T+T+ + G
Sbjct: 19316 DATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTITAENSSG 19375
Query: 1898 ------VVTTLENVSPPRRARVTDATETTITISWRTKTE----TITGFQVDAVPANGQTP 1947
+ L+ PP ++ +SW E IT + VD +
Sbjct: 19376 SKSATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYIVDKRETSRPNW 19435
Query: 1948 IQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVID---ASTAIDAPSNLR--- 2001
Q + + S ++ L G +Y+ + N PV + A D P
Sbjct: 19436 AQVSATVPITSCSVEKLIEGHEYQFRICAENKYGVGDPVFTEPAIAKNPYDPPGRCDPPV 19495
Query: 2002 FLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREVVPRPRPGVTEATI--TGLE 2055
T + + VSW+PP + ITGY++ EK + R + E T+ TGL+
Sbjct: 19496 ISNITKDHMTVSWKPPADDGGSPITGYLL--EKRETQAVNWTKVNRKPIIERTLKATGLQ 19553
Query: 2056 PGTEYTIYVIALKNNQKSEP 2075
GTEY V A+ +P
Sbjct: 19554 EGTEYEFRVTAINKAGPGKP 19573
Score = 98.6 bits (244), Expect = 7e-20
Identities = 157/730 (21%), Positives = 276/730 (37%), Gaps = 78/730 (10%)
Query: 785 KYIVNVYQISEDGEQSLIL-----STSQTTAP---DAPPDPT----VDQVDDTSIVVRWS 832
K + I + GE +L L +TS+T D P PT +D++D TSI + W
Sbjct: 29795 KLTIRETTIRDTGEYTLELKNVTGTTSETIKVIILDKPGPPTGPIKIDEIDATSITISWE 29854
Query: 833 RPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQE 888
P+ AP++GY + + ++ T ++ + L G +Y + A N+
Sbjct: 29855 PPELDGGAPLSGYVVEQRDAHRPGWLPVSESVTRSTFKFTRLTEGNEYVFRVAAT--NRF 29912
Query: 889 STPVVIQQETTGTPRSDTVPSPRD-LQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIP 943
+Q E S +P P + LQ +V+ +T+ W PPE S VTGY V+
Sbjct: 29913 GIGSYLQSEVIECRSSIRIPGPPETLQIFDVSRDGMTLTWYPPEDDGGSQVTGYIVERKE 29972
Query: 944 VNLPG-EHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSH------GRESKPLTAQQTTK 996
V ++P++ + TGL+ G+ Y +V A++ R SKP+ A
Sbjct: 29973 VRADRWVRVNKVPVTMTRYRS-TGLTEGLEYEHRVTAINARGSGKPSRPSKPIVAMDPIA 30031
Query: 997 LDA-PTNLQFVNETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPS-VSK 1050
P N + + T ++V + W+ P +++TGY + + + + + N P+ + +
Sbjct: 30032 PPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTKCNTTPTKIRE 30091
Query: 1051 YPLRNLQPASEYTVSLVAIK-GNQESPKATGVFTTLQPGSSIPPYNTE--------VTET 1101
Y L +L +EY ++A G P + P Y + V +
Sbjct: 30092 YTLTHLPQGAEYRFRVLACNAGGPGEPAEVPGTVKVTEMLEYPDYELDERYQEGIFVRQG 30151
Query: 1102 TIVITWTPAPRIGFKLGVRPSQGGEAPREV---TSDSGS-IVVSGLTPGVEYVYTIQVLR 1157
++ P F + +G + + TS++ + +V+ G Y + +
Sbjct: 30152 GVIRLTIPIKGKPFPICKWTKEGQDISKRAMIATSETHTELVIKEADRGDSGTYDLVLEN 30211
Query: 1158 DGQERDAPIVNKVV-TPLSPPTNLHLEANPDTGVLTVSWERSTTP---DITGYRITTTPT 1213
++ I +V+ +P SP L + + + VSW DI GY +
Sbjct: 30212 KCGKKAVYIKVRVIGSPNSPEGPLEYD-DIQVRSVRVSWRPPADDGGADILGYILERREV 30270
Query: 1214 NGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKD--------DKESVPISDTIIP 1265
+++ V +S L +EY+ V +E V + P
Sbjct: 30271 PKAAWYTIDSRVRG--TSLVVKGLKENVEYHFRVSAENQFGISKPLKSEEPVTPKTPLNP 30328
Query: 1266 EVPQLTDLSFVDITDSSIGLRWT---PLNSSTIIGYRITVVAAGEGIPIFEDFVDSSVGY 1322
P +D+T SS+ L W+ S + GY I + + +
Sbjct: 30329 PEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRVTGYYIERKETSTDKWVRHNKTQITTTM 30388
Query: 1323 YTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAVPPPTD-------LRFTNIGPDTMR 1375
YTVTGL P +Y +I + G S + ++ P D L +I D++
Sbjct: 30389 YTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCKDPFDKPSQPGELEILSISKDSVT 30448
Query: 1376 VTWAPPP---SIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSV 1432
+ W P ++ + V Y + D + LL TEY V +
Sbjct: 30449 LQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERIKDKQFTIGGLLEATEYEFRVFAE 30508
Query: 1433 YEQHESTPLR 1442
E S P R
Sbjct: 30509 NETGLSRPRR 30518
Score = 96.3 bits (238), Expect = 3e-19
Identities = 294/1454 (20%), Positives = 518/1454 (35%), Gaps = 209/1454 (14%)
Query: 684 IQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSA 743
I+ G Q + + + S P+T + P PL VT +TA ++W
Sbjct: 24772 IRTDGGQYILKLSNVGGTKSIPITVKVLDRPGPPEGPL-----KVTGVTAEKCYLAWNPP 24826
Query: 744 SDTVSGFRVEYELSEEGDEPQYLDLPSTATSVN-----IPDLLPGRKYI-----VNVYQI 793
G + + + E+ E L +T V + LLPG +YI VN Y I
Sbjct: 24827 LQD-GGANISHYIIEKR-ETSRLSWTQVSTEVQALNYKVTKLLPGNEYIFRVMAVNKYGI 24884
Query: 794 SEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRP----QAPITGYRIVYSPSV 849
E E + + + P P P V + S+VV W+RP I GY I+
Sbjct: 24885 GEPLESGPVTACNPYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGY-ILEKRDK 24943
Query: 850 EGSSTELNLPETANSVTL--SDLQPGVQYNITIYAVEE---NQESTPVVIQQETTGTPRS 904
EG +T + L + L G Y + A + S P V +
Sbjct: 24944 EGVRWTKCNKKTLTDLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYR------AC 24997
Query: 905 DTVPSPRDLQFVEVTDV---KVTIMWTPP----ESAVTGYRVDV------------IPVN 945
D + P +VTD V++ W+ P + V GY V+V P
Sbjct: 24998 DALYPPGPPSNPKVTDTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAADEWTTCTPPTG 25057
Query: 946 LPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLT------AQQ-----T 994
L G+ VT L Y F++ A++ +P T AQ+
Sbjct: 25058 LQGKQ-----------FTVTKLKENTEYNFRICAINSEGVGEPATLPGSVVAQERIEPPE 25106
Query: 995 TKLDAPTNLQFVNETDSTVLVRWT---PPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKY 1051
+LDA V +T+ + T P ++ + LT R Q V S +
Sbjct: 25107 IELDADLRKVVVLRASATLRLFVTIKGRPEPEVKWEKAEGILTDRA---QIEVTSSFTML 25163
Query: 1052 PLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAP 1111
+ N+ +L + V P + + EV + ++ ++W P
Sbjct: 25164 VIDNVTRFDSGRYNLTLENNSGSKTAFVNVRVLDSPSAPVNLTIREVKKDSVTLSWEPPL 25223
Query: 1112 RIGFKLGVRPSQGGEAPREVTSDSGSIV----------VSGLTPGVEYVYTIQVLRD--- 1158
G G + + RE T + + + + L G Y + + +
Sbjct: 25224 IDG---GAKITNYIVEKRETTRKAYATITNNCTKTTFRIENLQEGCSYYFRVLASNEYGI 25280
Query: 1159 GQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT---PDITGYRITTTPTNG 1215
G + KV P PP + L + T+ WE+ + ITGY +
Sbjct: 25281 GLPAETTEPVKVSEPPLPPGRVTL-VDVTRNTATIKWEKPESDGGSKITGYVVEMQTKGS 25339
Query: 1216 QQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPEVPQLTDLSF 1275
++ ++ +V + T L+ G EY V V + S P +P + + ++
Sbjct: 25340 EKWSTCTQVKTLE---ATISGLTAGEEYVFRVAAVNEKGRSDP-RQLGVPVIARDIEIK- 25394
Query: 1276 VDITDSSIGLRWTPLNSSTIIGYRITVVAAG----------EGIPIFEDFVDSSVGYYTV 1325
S+ L + N +I V G +G + E + TV
Sbjct: 25395 -----PSVELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTV 25449
Query: 1326 TGL--EPGIDYDISVITLI----NGGESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTWA 1379
T L + D+ L G + P T+ PP +R + D++ ++W
Sbjct: 25450 TSLSIKEASKEDVGTYELCVSNSAGSITVPITIIVLDRPGPPGPIRIDEVSCDSITISWN 25509
Query: 1380 PPP---SIDLTNFLVRYSPVKNEEDVAE---LSISPSDNAVVLTNLLPGTEYVVSVSS-- 1431
PP ++N++V K E +S + + ++ + L G+EY V +
Sbjct: 25510 PPEYDGGCQISNYIVE----KKETTSTTWHIVSQAVARTSIKIVRLTTGSEYQFRVCAEN 25565
Query: 1432 ---VYEQHESTPLRGRQKTGLDSPTGI-DFSDITANSFTVHWIAP----RATITGYRIRH 1483
ES+ + P G T ++ V W P + + GY + +
Sbjct: 25566 RYGKSSYSESSAVVAEYPFSPPGPPGTPKVVHATKSTMLVTWQVPVNDGGSRVIGYHLEY 25625
Query: 1484 HPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN----GREESPLLIGQQSTVS 1539
+ +++ + + ++ L G Y + A N G+
Sbjct: 25626 KERSSILWSKANKILIADTQMKVSGLDEGLMYEYRVYAENIAGIGKCSKSCEPVPARDPC 25685
Query: 1540 DVPRDLEVVAATPTSLLISWDAP----AVTVRYYRITYGETGGNSPVQEFTVPGSKSTAT 1595
D P EV T S+ + W P + Y + E ++ ++
Sbjct: 25686 DPPGQPEVTNITRKSVSLKWSKPHYDGGAKITGYIVERRELPDGRWLKCNYTNIQETYFE 25745
Query: 1596 ISGLKPGVDYTITVYAVTGRGD-SPASSKPISINYRTEIDKPSQMQVTDVQDNSI--SVK 1652
++ L Y V+A S S I + +++ P M +D + + +
Sbjct: 25746 VTELTEDQRYEFRVFARNAADSVSEPSESTGPIIVKDDVEPPRVMMDVKFRDVIVVKAGE 25805
Query: 1653 WLPSSSPVTG--YRVTTTPKNG---PGPTKTKTAGPD-QTEMTIEGL--QPTVEYVVSVY 1704
L ++ + G V + K+G +T+ D T +T++ + T +YV+++
Sbjct: 25806 VLKINADIAGRPLPVISWAKDGIEIEERARTEIISTDNHTLLTVKDCIRRDTGQYVLTL- 25864
Query: 1705 AQNPSGESQPLVQTAVTNIDRPKG--LAFTDVDVDSIKIAWESPQ----GQVSRYRVTYS 1758
+N +G V V + P L + + ++W PQ + Y V
Sbjct: 25865 -KNVAGTRSVAVNCKVLDKPGPPAGPLEINGLTAEKCSLSWGRPQEDGGADIDYYIV--- 25920
Query: 1759 SPEDGIHELFPAPDGE--EDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPA- 1815
+ H + +GE + ++ L G+EY V ++ +PL +S AI A
Sbjct: 25921 EKRETSHLAWTICEGELQMTSCKVTKLLKGNEYIFRVTGVNKYGVGEPL---ESVAIKAL 25977
Query: 1816 --------PTDLKFTQVTPTSLSAQWTPP----NVQLTGYRVRVTPKEKTGPMKEINLAP 1863
PT L+ T VT S++ W+ P +++GY + K ++
Sbjct: 25978 DPFTVPSPPTSLEITSVTKESMTLCWSRPESDGGSEISGYIIERREKNSLRWVRVNKKPV 26037
Query: 1864 DSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQ--GVVTTLENV---SPPRRARVTDATE 1918
V +GL +YE VYA S P++ ++ + V SPP + ++ D+ +
Sbjct: 26038 YDLRVKSTGLREGCEYEYRVYAENAAGLSLPSETSPLIRAEDPVFLPSPPSKPKIVDSGK 26097
Query: 1919 TTITISWRTKT----ETITGFQVD---AVPANGQTPIQRTIKPDVRSYTITGLQPGTDYK 1971
TTITI+W ITG+ V+ + + +T IQ + YTI+GL G +Y
Sbjct: 26098 TTITIAWVKPLFDGGAPITGYTVEYKKSDDTDWKTSIQSLRGTE---YTISGLTTGAEYV 26154
Query: 1972 IYLYTLNDNARSSP 1985
+ ++N S P
Sbjct: 26155 FRVKSVNKVGASDP 26168
Score = 95.5 bits (236), Expect = 6e-19
Identities = 319/1473 (21%), Positives = 540/1473 (36%), Gaps = 232/1473 (15%)
Query: 777 IPDLLPGRKYIVNVYQISEDG--EQSLILSTSQTTAPDAPPD------PTVDQVDDTSIV 828
+ DL+ G +Y V ++ G + S + PD PP V++ + +IV
Sbjct: 16078 VEDLVEGGEYEFRVKAVNAAGVSKPSATVGPCDCQRPDMPPSIDLKEFMEVEEGTNVNIV 16137
Query: 829 VR----------WSR--PQAPITGYRIVYSPSVE----GSSTELNLPETANSVTLSDLQP 872
+ W + P+ P ++Y V + L +P++ S T
Sbjct: 16138 AKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDT------ 16191
Query: 873 GVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE- 931
G+ TI AV N + ++ G P P ++F V+ ++T+ W PP+
Sbjct: 16192 GLY---TITAVN-NLGTASKEMRLNVLGRPGPPVGP----IKFESVSADQMTLSWFPPKD 16243
Query: 932 ---SAVTGYRVDVIPVNLPG-EHGQRLPISRNTFAEVTGLSPGVTYYFKVFA-----VSH 982
S +T Y ++ N H P + + L G Y F++ A +
Sbjct: 16244 DGGSKITNYVIEKREANRKTWVHVSSEP--KECTYTIPKLLEGHEYVFRIMAQNKYGIGE 16301
Query: 983 GRESKPLTAQQTTKLD-APTNLQFVNETDSTVLVRWTPPR----AQITGYRLTVGLTRRG 1037
+S+P TA+ + AP + T +++ V W P + +TGY L + T
Sbjct: 16302 PLDSEPETARNLFSVPGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPVTGYWLEMKDTTSK 16361
Query: 1038 QPRQYNVGPSVS-----KYPLRNLQPASEYTVSLVAIKGNQESPK------ATGVFTTLQ 1086
+ ++ N P + Y + L S+Y + AI P AT
Sbjct: 16362 RWKRVNRDPIKAMTLGVSYKVTGLIEGSDYQFRVYAINAAGVGPASLPSDPATARDPIAP 16421
Query: 1087 PGSSIPPYNTEVTETTIVITWTPAPRIGFKLG----VRPSQGGEAPREVTSDSG----SI 1138
PG P T+ T+++ + W+P + G V + G+ E D +
Sbjct: 16422 PGPPFPKV-TDWTKSSADLEWSPPLKDGGSKVTGYIVEYKEEGKEEWEKGKDKEVRGTKL 16480
Query: 1139 VVSGLTPGVEYVYTIQVLRD---GQERDAPIVNKVVTPLSPPTNLHLEANP-DTGVLTVS 1194
VV+GL G Y + ++ + G+ + V ++ L P +L L+A+ D V+
Sbjct: 16481 VVTGLKEGAFYKFRVRAVNIAGIGEPGEVTDVIEMKDRLVSP-DLQLDASVRDRIVVHAG 16539
Query: 1195 WERSTTPDITGYRITTTPTNGQQGNSLEEVV---HADQSSCTFDNLSPGLEYNVSVYTVK 1251
++G T N + +E A SS N + VY++
Sbjct: 16540 GVIRIIAYVSGKPPPTVTWNMNERTLPQEATIETTAISSSMVIKNCQRSHQ---GVYSLL 16596
Query: 1252 DDKESVPISDTIIPEV-----PQLTDLSFVDITDSSIGLRW-TPLNS--STIIGYRITVV 1303
E+ TII +V P T ++T+ S L W +P + S I Y I
Sbjct: 16597 AKNEAGERKKTIIVDVLDVPGPVGTPFLAHNLTNESCKLTWFSPEDDGGSPITNYVIEKR 16656
Query: 1304 AAGEGI--PIFEDFVDSSVGYYTVTGLEPGIDY--DISVITLINGGESAPTT----LTQQ 1355
+ P+ + TV GL G Y I+ I G T+ + +
Sbjct: 16657 ESDRRAWTPVTYTVTRQNA---TVQGLIQGKAYFFRIAAENSIGMGPFVETSEALVIREP 16713
Query: 1356 TAVPP-PTDLRFTNIGPDTMRVTWAPPP---SIDLTNFLVRYSPVKNEEDVAELSISPSD 1411
VP P DL + +T+ +TW PP ++ N+++ + E+ + +
Sbjct: 16714 ITVPERPEDLEVKEVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEKFHKVTNDNLLS 16773
Query: 1412 NAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQ----KTGLDSPT-GIDFSDITANSFT 1466
+ L G Y VS+V + P + K L PT +DF D T
Sbjct: 16774 RKYTVKGLKEGDTYEYRVSAVNIVGQGKPSFCTKPITCKDELAPPTLHLDFRD----KLT 16829
Query: 1467 VHWIAPRATITGYRIRHHPEHFSGRPR------EDRVPHSRNSITLTNLTPGTEYVVSIV 1520
+ + +TG +SG+P+ +D + T TP T + I
Sbjct: 16830 IR-VGEAFALTG--------RYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATLALEKIK 16880
Query: 1521 ALNGREESPLLIGQQST--------VSDVPRDLEVVA------ATPTSLLISWDAP---- 1562
A ++ + ST V+ V R V T ++ISW P
Sbjct: 16881 AKRSDSGKYCVVVENSTGSRKGFCQVNVVDRPGPPVGPVSFDEVTKDYMVISWKPPLDDG 16940
Query: 1563 AVTVRYYRITYGETGGN--SPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDS-P 1619
+ Y I E G + PV T +K+T +S L G DY ++A G S P
Sbjct: 16941 GSKITNYIIEKKEVGKDVWMPV---TSASAKTTCKVSKLLEGKDYIFRIHAENLYGISDP 16997
Query: 1620 ASSKPISINYRTEI-DKPSQMQVTDVQDNSISVKWLP---SSSPVTGY---RVTTTPKNG 1672
S + R + D P Q VT+V +S V W P+T Y + T K
Sbjct: 16998 LVSDSMKAKDRFRVPDAPDQPIVTEVTKDSALVTWNKPHDGGKPITNYILEKRETMSKRW 17057
Query: 1673 PGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQN------PSGESQPL-VQTAVTNIDR 1725
TK T+ + L +Y V A+N PS S+P+ + +
Sbjct: 17058 ARVTKDPIH--PYTKFRVPDLLEGCQYEFRVSAENEIGIGDPSPPSKPVFAKDPIAKPSP 17115
Query: 1726 PKGLAFTDVDVDSIKIAWESPQ----GQVSRYRVTYSSPEDGI-HELFPAPDGEEDTA-E 1779
P D +S+ + W+ P+ ++ Y V Y D P+ +T +
Sbjct: 17116 PVNPEAIDTTCNSVDLTWQPPRHDGGSKILGYIVEYQKVGDEEWRRANHTPESCPETKYK 17175
Query: 1780 LQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTS-LSAQWTPPNV 1838
+ GLR G Y V+A++ ES P +P P +K P L A
Sbjct: 17176 VTGLRDGQTYKFRVLAVNAAGESDP------AHVPEPVLVKDRLEPPELILDANMAREQH 17229
Query: 1839 QLTGYRVRVT------PKEKTGPMKEINLAPDSSSVVVSGLMVATKYEV--------SVY 1884
G +R++ P K KE AP + + V+ V +K E+ +Y
Sbjct: 17230 IKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARIDVTP--VGSKLEIRNAAHEDGGIY 17287
Query: 1885 AL--KDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTE----TITGFQVD 1938
+L ++ S+ V L+ PPR V++ + + ++W+ + IT + V+
Sbjct: 17288 SLTVENPAGSKTVSVKVLVLDKPGPPRDLEVSEIRKDSCYLTWKEPLDDGGSVITNYVVE 17347
Query: 1939 A--VPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPV-------VID 1989
V + +P+ T K +S+ L G Y + N R V +D
Sbjct: 17348 RRDVASAQWSPLSATSKK--KSHFAKHLNEGNQYLFRVAAENQYGRGPFVETPKPIKALD 17405
Query: 1990 ASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREVVPRPRPG 2045
P +L + + + W P + ITGY+++Y++ G+ ++ +
Sbjct: 17406 PLHPPGPPKDLHHVDVDKTEVSLVWNKPDRDGGSPITGYLVEYQEEGT--QDWIKFKTVT 17463
Query: 2046 VTEATITGLEPGTEYTIYVIALKNNQKSEPLIG 2078
E +TGL+ G Y V K+E ++G
Sbjct: 17464 NLECVVTGLQQGKTYRFRV-------KAENIVG 17489
Score = 95.1 bits (235), Expect = 7e-19
Identities = 312/1572 (19%), Positives = 569/1572 (36%), Gaps = 228/1572 (14%)
Query: 616 ITETPSQPNSHPIQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLK 672
+T T S + W P+ S + Y++ +PK + +W N+ + GL
Sbjct: 24219 VTLTDVSQTSASLMWEKPEHDGGSRVLGYVVEMQPKGTE-KWSIVAESKVCNA-VVTGLS 24276
Query: 673 PGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETT---PFSP--LVATSES 727
G Y+ ++ + + G + PV + +T + + PF+ + A +
Sbjct: 24277 SGQEYQFRVKAYNEKGKSD-------PRVLGVPVIAKDLTIQPSLKLPFNTYSIQAGEDL 24329
Query: 728 VTEITASSFV---VSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGR 784
EI +SWV + + + +++ TATS + + G
Sbjct: 24330 KIEIPVIGRPRPNISWVKDGEPLK-------------QTTRVNVEETATST-VLHIKEGN 24375
Query: 785 KYIVNVYQISED---GEQSLILSTSQTTAPDAPPDPT-VDQVDDTSIVVRWSRPQ----A 836
K Y ++ G + LS P P P D+V +V+ W P
Sbjct: 24376 KDDFGKYTVTATNSAGTATENLSVIVLEKPGPPVGPVRFDEVSADFVVISWEPPAYTGGC 24435
Query: 837 PITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQ 896
I+ Y + + + ++ ++ ++ L+ G +Y I+A +S P+ +
Sbjct: 24436 QISNYIVEKRDTTTTTWHMVSATVARTTIKITKLKTGTEYQFRIFAENRYGKSAPLDSKA 24495
Query: 897 ETTGTPRSDTVPSPRDLQFV-EVTDVKVTIMWTPPES----AVTGYRVDVIPVN-LPGEH 950
P + P P FV ++ ++ + W P + + GY ++ N +
Sbjct: 24496 VIVQYPFKE--PGPPGTPFVTSISKDQMLVQWHEPVNDGGTKIIGYHLEQKEKNSILWVK 24553
Query: 951 GQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQT----TKLDAPTNLQFV 1006
+ PI F + TGL G+ Y FKV A + KP + D P + +
Sbjct: 24554 LNKTPIQDTKF-KTTGLDEGLEYEFKVSAENIVGIGKPSKVSECFVARDPCDPPGRPEAI 24612
Query: 1007 NETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSV-SKYPLRNLQPASE 1061
T + V ++W P ++ITGY + G+ + + + +++ + L
Sbjct: 24613 VITRNNVTLKWKKPAYDGGSKITGYIVEKKDLPDGRWMKASFTNVLETEFTVSGLVEDQR 24672
Query: 1062 YTVSLVA--IKGNQESPK-ATGVFTTLQ----PGSSIPPYNTEVT-----ETTIV---IT 1106
Y ++A GN P ++G T P +S+ P +V ET ++ I
Sbjct: 24673 YEFRVIARNAAGNFSEPSDSSGAITARDEIDAPNASLDPKYKDVIVVHAGETFVLEADIR 24732
Query: 1107 WTPAPRIGFKLGVRPSQGGEAPREVTS--DSGSIVVSGL--TPGVEYVYTIQVLRDGQER 1162
P P + + + + A E+ S ++VV T G +Y+ +++ G +
Sbjct: 24733 GKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQYI--LKLSNVGGTK 24790
Query: 1163 DAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWE---RSTTPDITGYRITTTPTNGQQGN 1219
PI KV+ PP ++W + +I+ Y I T+
Sbjct: 24791 SIPITVKVLDRPGPPEGPLKVTGVTAEKCYLAWNPPLQDGGANISHYIIEKRETSRLSWT 24850
Query: 1220 SLEEVVHADQSSCTFDNLSPGLEY-----NVSVYTVKDDKESVPIS---------DTIIP 1265
+ V A T L PG EY V+ Y + + ES P++ P
Sbjct: 24851 QVSTEVQALNYKVT--KLLPGNEYIFRVMAVNKYGIGEPLESGPVTACNPYKPPGPPSTP 24908
Query: 1266 EVPQLTDLSFV-----DITDSSI-------------GLRWTPLNSSTIIGYRITVVAAGE 1307
EV +T S V + D G+RWT N T+ R+ V E
Sbjct: 24909 EVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDKEGVRWTKCNKKTLTDLRLRVTGLTE 24968
Query: 1308 GIPI-FEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAVPPPTDLRF 1366
G F +++ G + EP + Y G PP++ +
Sbjct: 24969 GHSYEFRVAAENAAGVGEPS--EPSVFYRACDALYPPG---------------PPSNPKV 25011
Query: 1367 TNIGPDTMRVTWAPP---PSIDLTNFLVRYSPVKNEE-DVAELSISPSDNAVVLTNLLPG 1422
T+ ++ + W+ P + ++V +E +T L
Sbjct: 25012 TDTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAADEWTTCTPPTGLQGKQFTVTKLKEN 25071
Query: 1423 TEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGY-RI 1481
TEY + ++ + P ++ A+ V + AT+ + I
Sbjct: 25072 TEYNFRICAINSEGVGEPATLPGSVVAQERIEPPEIELDADLRKVVVLRASATLRLFVTI 25131
Query: 1482 RHHPEHFSGRPREDRVPHSRNSITLT---------NLTPGTEYVVSIVALNGREESPLLI 1532
+ PE + + + R I +T N+T ++ N +
Sbjct: 25132 KGRPEPEVKWEKAEGILTDRAQIEVTSSFTMLVIDNVTRFDSGRYNLTLENNSGSKTAFV 25191
Query: 1533 GQQSTVS-DVPRDLEVVAATPTSLLISWDAPAVT----VRYYRITYGETGGNSPVQEFTV 1587
+ S P +L + S+ +SW+ P + + Y + ET + T
Sbjct: 25192 NVRVLDSPSAPVNLTIREVKKDSVTLSWEPPLIDGGAKITNYIVEKRETTRKA-YATITN 25250
Query: 1588 PGSKSTATISGLKPGVDYTITVYAVT--GRGDSPASSKPISINYRTEIDKPSQMQVTDVQ 1645
+K+T I L+ G Y V A G G +++P+ ++ P ++ + DV
Sbjct: 25251 NCTKTTFRIENLQEGCSYYFRVLASNEYGIGLPAETTEPVKVSEPPL--PPGRVTLVDVT 25308
Query: 1646 DNSISVKW-LPSS---SPVTGYRVTTTPKNGPGPTKTKTAGPDQT-EMTIEGLQPTVEYV 1700
N+ ++KW P S S +TGY V K G K T +T E TI GL EYV
Sbjct: 25309 RNTATIKWEKPESDGGSKITGYVVEMQTK---GSEKWSTCTQVKTLEATISGLTAGEEYV 25365
Query: 1701 VSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVD-SIKIAWESPQGQVSRYRVTYSS 1759
V A N G S P Q V I R D+++ S+++ + + + +R ++
Sbjct: 25366 FRVAAVNEKGRSDPR-QLGVPVIAR-------DIEIKPSVELPFHTFNVK-AREQLKIDV 25416
Query: 1760 PEDGIHELFP--APDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQ-------- 1809
P G + DG+ E + S TV+ +++ + S+ +GT
Sbjct: 25417 PFKGRPQATVNWRKDGQT-LKETTRVNVSSSKTVTSLSIKE--ASKEDVGTYELCVSNSA 25473
Query: 1810 -STAIPA----------PTDLKFTQVTPTSLSAQWTPPNV----QLTGYRVRVTPKEKTG 1854
S +P P ++ +V+ S++ W PP Q++ Y V KE T
Sbjct: 25474 GSITVPITIIVLDRPGPPGPIRIDEVSCDSITISWNPPEYDGGCQISNYIVE--KKETTS 25531
Query: 1855 PMKEI-NLAPDSSSVVVSGLMVATKYEVSVYAL----KDTLTSRPAQGVVTTLENVSPPR 1909
I + A +S+ + L ++Y+ V A K + + A PP
Sbjct: 25532 TTWHIVSQAVARTSIKIVRLTTGSEYQFRVCAENRYGKSSYSESSAVVAEYPFSPPGPPG 25591
Query: 1910 RARVTDATETTITISWRTKT----ETITGFQVDAVPANG--QTPIQRTIKPDVRSYTITG 1963
+V AT++T+ ++W+ + G+ ++ + + + + D + ++G
Sbjct: 25592 TPKVVHATKSTMLVTWQVPVNDGGSRVIGYHLEYKERSSILWSKANKILIADTQ-MKVSG 25650
Query: 1964 LQPGTDYKIYLYTLN----DNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPR- 2018
L G Y+ +Y N S + A D P T S+ + W P
Sbjct: 25651 LDEGLMYEYRVYAENIAGIGKCSKSCEPVPARDPCDPPGQPEVTNITRKSVSLKWSKPHY 25710
Query: 2019 ---ARITGYIIK 2027
A+ITGYI++
Sbjct: 25711 DGGAKITGYIVE 25722
Score = 94.7 bits (234), Expect = 1e-18
Identities = 315/1607 (19%), Positives = 572/1607 (35%), Gaps = 282/1607 (17%)
Query: 628 IQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISI 684
+ W P+ + I Y++ K W + + GL G Y ++ ++
Sbjct: 14002 LNWTKPEHDGGAKIESYVIEML-KTGTDEWVRVAEGVPTTQHLLPGLMEGQEYSFRVRAV 14060
Query: 685 QQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSAS 744
+ G E + S+ V + P V IT ++ + W +
Sbjct: 14061 NKAGESEPSE------------PSDPVLCREKLYPPSPPRWLEVINITKNTADLKW-TVP 14107
Query: 745 DTVSGFRVEYELSEEGDEP----QYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGE-- 798
+ G + + E+ D Q +D T + L G Y+ V + G+
Sbjct: 14108 EKDGGSPITNYIVEKRDVRRKGWQTVDTTVKDTKCTVTPLTEGSLYVFRVAAENAIGQSD 14167
Query: 799 ----QSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ----APITGYRIVYSPSVE 850
+ +L+ T P P V V + ++W P+ PI Y I +
Sbjct: 14168 YTEIEDSVLAKDTFTTPGPPYALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKERL- 14226
Query: 851 GSSTELNLPETAN---SVTLSDLQPGVQYNITIYAVEEN-----QESTPVVIQQETTGTP 902
+ + +TA + ++D+ G + + A E E T ++ ++ T P
Sbjct: 14227 -GTRWVKAGKTAGPDCNFRVTDVIEGTEVQFQVRAENEAGVGHPSEPTEILSIEDPTSPP 14285
Query: 903 RSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPVNLPGEHGQRL---P 955
P DL + + I W PPE S + GY V++ PV E R+ P
Sbjct: 14286 SP-----PLDLHVTDAGRKHIAIAWKPPEKNGGSPIIGYHVEMCPVGT--EKWMRVNSRP 14338
Query: 956 ISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLV 1015
I F G+ P Y +V AV+ S+P + P ++ ++V
Sbjct: 14339 IKDLKFKVEEGVVPDKEYVLRVRAVNAIGVSEPSEISENVVAKDPDCKPTIDLETHDIIV 14398
Query: 1016 RWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPL-RNLQPASEYTVSLVAIKGNQE 1074
I G +L++ + R P P+VS + + ++ + T+ I + E
Sbjct: 14399 --------IEGEKLSIPVPFRAVPV-----PTVSWHKDGKEVKASDRLTMKNDHISAHLE 14445
Query: 1075 SPKAT----GVFT-TLQP--GSSIPPYN---------------TEVTETTIVITWTP--- 1109
PK+ G++T TL+ GS+ N +++T+++ +TW P
Sbjct: 14446 VPKSVRADAGIYTITLENKLGSATASINVKVIGLPGPCKDIKASDITKSSCKLTWEPPEF 14505
Query: 1110 ---APRIGFKLGVRPSQGGEAPREVTSDSGSI--VVSGLTPGVEYVYTIQVLRD-GQERD 1163
P + + L R + G V S + V L P EY + ++ + G
Sbjct: 14506 DGGTPILHYVLERREA-GRRTYIPVMSGENKLSWTVKDLIPNGEYFFRVKAVNKVGGGEY 14564
Query: 1164 APIVNKVVT-----PLSPPTNLHLEANPDTGVLTVSWERSTTPD---ITGYRITTTPTNG 1215
+ N V+ P PP ++ + NP +T++W+ I GY I
Sbjct: 14565 IELKNPVIAQDPKQPPDPPVDVEVH-NPTAEAMTITWKPPLYDGGSKIMGYIIEKIAKGE 14623
Query: 1216 QQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYT-----VKDDKESVPISDTIIP-EVPQ 1269
++ E + + T L G EY V + + + P + + P + P+
Sbjct: 14624 ERWKRCNEHL-VPILTYTAKGLEEGKEYQFRVRAENAAGISEPSRATPPTKAVDPIDAPK 14682
Query: 1270 LTDLSFVDIT-------DSSIG------LRWTPLNSSTIIGYRITVVAA-------GEGI 1309
+ + +++ D+SI + W + + I+ I AA GE +
Sbjct: 14683 VILRTSLEVKRGDEIALDASISGSPYPTITWIK-DENVIVPEEIKKRAAPLVRRRKGE-V 14740
Query: 1310 PIFEDFVDSSVGYYTVTGLEPGI-----------DYDISVITLIN--GGESAPTTLTQQT 1356
E FV ++ + G D+ + +I + N G AP T++
Sbjct: 14741 QEEEPFVLPLTQRLSIDNSKKGESQLRVRDSLRPDHGLYMIKVENDHGIAKAPCTVSVLD 14800
Query: 1357 AVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVL 1416
PP + F +I ++ W PP D + ++ Y+ K ++ P +V+
Sbjct: 14801 TPGPPINFVFEDIRKTSVLCKWEPPLD-DGGSEIINYTLEKKDK------TKPDSEWIVV 14853
Query: 1417 TNLLPGTEYVVSVSSVYEQHE------------------STPLRGRQKTG-LDSPTGIDF 1457
T+ L +Y SV+ + E E S PL + G D+P
Sbjct: 14854 TSTLRHCKY--SVTKLIEGKEYLFRVRAENRFGPGPPCVSKPLVAKDPFGPPDAPDKPIV 14911
Query: 1458 SDITANSFTVHWIAPR---ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTE 1514
D+T+NS V W P+ + I GY + + + R ++ + + L G
Sbjct: 14912 EDVTSNSMLVKWNEPKDNGSPILGYWLEKREVNSTHWSRVNKSLLNALKANVDGLLEGLT 14971
Query: 1515 YVVSIVALN----GREESPLLIGQQSTVSD--------VPRDLEVVAATPTSLLISWDAP 1562
YV + A N G+ P T D +PR V + T++ + W+ P
Sbjct: 14972 YVFRVCAENAAGPGKFSPP---SDPKTAHDPISPPGPPIPR---VTDTSSTTIELEWEPP 15025
Query: 1563 AVT----VRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDS 1618
A + Y + G N + T+ ++ G DY + V AV G+
Sbjct: 15026 AFNGGGEIVGYFVDKQLVGTNEWSRCTEKMIKVRQYTVKEIREGADYKLRVSAVNAAGEG 15085
Query: 1619 -PASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTK 1677
P ++P+++ E +P +++ +SVK R+ P PTK
Sbjct: 15086 PPGETQPVTV---AEPQEPPAVEL------DVSVKGGIQIMAGKTLRIPAVVTGRPVPTK 15136
Query: 1678 --TKTAGP-DQTEMTIEGLQPTVEYVVS-----------VYAQNPSGESQPLVQTAVTNI 1723
TK G D+ + I+ + E ++ + A N G + V ++
Sbjct: 15137 VWTKEEGELDKDRVVIDNVGTKSELIIKDALRKDHGRYVITATNSCGSKFAAARVEVFDV 15196
Query: 1724 DRP-KGLAFTDVDVDSIKIAWESPQ----GQVSRYRVTYSSPEDGIHELFPAPDGEEDTA 1778
P L + + W P+ +++ + + + +H + E
Sbjct: 15197 PGPVLDLKPVVTNRKMCLLNWSDPEDDGGSEITGFIIERKDAK--MHTWRQPIETERSKC 15254
Query: 1779 ELQGLRPGSEYTVSVVALH-----DDMESQPLIGTQSTAIP-APTDLKFTQVTPTSLSAQ 1832
++ GL G EY V+A + +E P++ P +P L +T+ T ++++
Sbjct: 15255 DITGLLEGQEYKFRVIAKNKFGCGPPVEIGPILAVDPLGPPTSPERLTYTERTKSTITLD 15314
Query: 1833 WTPPNVQ----LTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKD 1888
W P + GY + +K + ++S +V L YE V A+ +
Sbjct: 15315 WKEPRSNGGSPIQGYIIEKRRHDKPDFERVNKRLCPTTSFLVENLDEHQMYEFRVKAVNE 15374
Query: 1889 TLTSRPA--QGVVTTLENVSPPRRARVTDATETTIT-------------------ISWRT 1927
S P+ VV + V P + R++ +T I W +
Sbjct: 15375 IGESEPSLPLNVVIQDDEVPPTIKLRLSVRGDTIKVKAGEPVHIPADVTGLPMPKIEW-S 15433
Query: 1928 KTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVV 1987
K ET+ DA+ + + K ++ GT YT+ + R V
Sbjct: 15434 KNETVIEKPTDALQITKEEVSRSEAKTELSIPKAVREDKGT------YTVTASNRLGSVF 15487
Query: 1988 IDASTAI-DAPSNLRFLATT---PNSLLVSWQPP----RARITGYII 2026
+ + D PS R LA T S ++W P + IT Y+I
Sbjct: 15488 RNVHVEVYDRPSPPRNLAVTDIKAESCYLTWDAPLDNGGSEITHYVI 15534
Score = 94.0 bits (232), Expect = 2e-18
Identities = 154/662 (23%), Positives = 253/662 (38%), Gaps = 93/662 (14%)
Query: 1538 VSDVP---RDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTA 1594
V DVP R+LEV + ++W+ P I Y + + + + ++ +
Sbjct: 13086 VIDVPGPVRNLEVTETFDGEVSLAWEEPLTDGGSKIIGYVVERRDIKRKTWVLATDRAES 13145
Query: 1595 ---TISGL-KPGVDYTITVYAVT--GRGDSPASSKPISINYRTEIDKPS-QMQVTDVQDN 1647
T++GL K GV+Y V A G G+ + P+ + ++ P + +TDV
Sbjct: 13146 CEFTVTGLQKGGVEYLFRVSARNRVGTGEPVETDNPVEARSKYDVPGPPLNVTITDVNRF 13205
Query: 1648 SISVKWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSV 1703
+S+ W P + +T Y + K T + T+ + EY V
Sbjct: 13206 GVSLTWEPPEYDGGAEITNYVIELRDKTSIRWDTAMTVRAEDLSATVTDVVEGQEYSFRV 13265
Query: 1704 YAQNPSGESQPLVQTAVTN----IDRPK---GLAFTDVDVDSIKIAWESPQGQVSRYRVT 1756
AQN G +P T I+RP L +D S+++ WE P +
Sbjct: 13266 RAQNRIGVGKPSAATPFVKVADPIERPSPPVNLTSSDQTQSSVQLKWEPPLKDGGSPILG 13325
Query: 1757 Y--SSPEDGIH-------ELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIG 1807
Y E+G +L P E T ++ GL G++Y V A + S P
Sbjct: 13326 YIIERCEEGKDNWIRCNMKLVP-----ELTYKVTGLEKGNKYLYRVSAENKAGVSDP--- 13377
Query: 1808 TQSTAIPAPTDLKFTQVTPT-SLSA-----QWTPPN-----VQLTGY-RVRVT-----PK 1850
+ I P V PT LSA + PN V TGY R T
Sbjct: 13378 ---SEILGPLTADDAFVEPTMDLSAFKDGLEVIVPNPITILVPSTGYPRPTATWCFGDKV 13434
Query: 1851 EKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGV--VTTLENVSPP 1908
+TG ++ + +V+S + + + +Y LK + G V + S P
Sbjct: 13435 LETGDRVKMKTLSAYAELVISP---SERSDKGIYTLKLENRVKTISGEIDVNVIARPSAP 13491
Query: 1909 RRARVTDATETTITISWRTKTET----ITGFQVDAVPANGQTPIQRTIKPDVRSYTITGL 1964
+ + D T+ ++ ++W + +TG+ V+ + +T + +T+ L
Sbjct: 13492 KELKFGDITKDSVHLTWEPPDDDGGSPLTGYVVEKREVSRKTWTKVMDFVTDLEFTVPDL 13551
Query: 1965 QPGTDYKIYLYTLNDNARSSPVVIDA-------STAIDAPSNLRFLATTPNSLLVSWQPP 2017
G +Y + N P +D +T D P N+++ T NS+ ++W PP
Sbjct: 13552 VQGKEYLFKVCARNKCGPGEPAYVDEPVNMSTPATVPDPPENVKWRDRTANSIFLTWDPP 13611
Query: 2018 R----ARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKS 2073
+ +RI GYI++ GS P T+ +TGLE G Y V AL S
Sbjct: 13612 KNDGGSRIKGYIVERCPRGSDKWVACGEP-VAETKMEVTGLEEGKWYAYRVKALNRQGAS 13670
Query: 2074 EPLIGRKKTDELPQLVTLPHPNLHGPEILDVPSTVQKTPFVTHPGYDTGNGIQLPGTSGQ 2133
+P + T+E+ + T P + LDV T G I+LP T
Sbjct: 13671 KP---SRPTEEIQAVDTQEAPEI----FLDVKLLAGLT-------VKAGTKIELPATVTG 13716
Query: 2134 QP 2135
+P
Sbjct: 13717 KP 13718
Score = 90.5 bits (223), Expect = 2e-17
Identities = 354/1666 (21%), Positives = 582/1666 (34%), Gaps = 229/1666 (13%)
Query: 624 NSHPIQWNAPQ---PSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKG--LKPGVVYE 678
+S + W P+ S I+ YI+ R S W+ + + TIK LK G Y+
Sbjct: 22256 DSITLSWGPPKYDGGSSINNYIVEKRD-TSTTTWQ--IVSATVARTTIKACRLKTGCEYQ 22312
Query: 679 GQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVV 738
++ + +YG + T V P +P+V S + S V
Sbjct: 22313 FRIAAENRYGKSTYLNSEPTVAQYPFKVPG-------PPGTPVVTLS------SRDSMEV 22359
Query: 739 SWVSASDTVSGFRVEYELS-EEGDEPQYLDL---PSTATSVNIPDLLPGRKYI--VNVYQ 792
W + Y L +E + ++ L P T L G +Y V+
Sbjct: 22360 QWNEPISDGGSRVIGYHLERKERNSILWVKLNKTPIPQTKFKTTGLEEGVEYEFRVSAEN 22419
Query: 793 ISEDGEQSLILSTSQTTAPDAPPD-PTVDQVDDTSIVVRWSRPQ----APITGYRIVYSP 847
I G+ S + P PP P V S+ ++W +P + ITGY +
Sbjct: 22420 IVGIGKPSKVSECYVARDPCDPPGRPEAIIVTRNSVTLQWKKPTYDGGSKITGYIVEKKE 22479
Query: 848 SVEG---SSTELNLPETANSVTLSDLQPGVQYNITIYA------VEENQESTPVVIQQET 898
EG ++ N+ +T VT L +Y + A E EST + ++
Sbjct: 22480 LPEGRWMKASFTNIIDTHFEVT--GLVEDHRYEFRVIARNAAGVFSEPSESTGAITARDE 22537
Query: 899 TGTPRSDTVPSPRDLQFVEVTD---VKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLP 955
PR P +D V + V I P + + I + + RL
Sbjct: 22538 VDPPRISMDPKYKDTIVVHAGESFKVDADIYGKPIPT------IQWIKGDQELSNTARLE 22591
Query: 956 ISRNTFAEVTGLSPGV-----TYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNE-T 1009
I FA + V Y K V+ G S + + + P ++ T
Sbjct: 22592 IKSTDFATSLSVKDAVRVDSGNYILKAKNVA-GERSVTVNVKVLDRPGPPEGPVVISGVT 22650
Query: 1010 DSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVS 1065
+ W PP + I Y + T R + + L +EYT
Sbjct: 22651 AEKCTLAWKPPLQDGGSDIINYIVERRETSRLVWTVVDANVQTLSCKVTKLLEGNEYTFR 22710
Query: 1066 LVAIKGNQ-----ESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWT-PAPR-----IG 1114
++A+ ES + P + P T VT+ ++++ W PA +G
Sbjct: 22711 IMAVNKYGVGEPLESEPVVAKNPFVVPDAPKAPEVTTVTKDSMIVVWERPASDGGSEILG 22770
Query: 1115 FKLGVRPSQGGEAPREVTSDSGSIV--VSGLTPGVEYVYTIQVLRD-GQERDAP--IVNK 1169
+ L R +G R G + V+GL +Y + + G +P K
Sbjct: 22771 YVLEKRDKEGIRWTRCHKRLIGELRLRVTGLIENHDYEFRVSAENAAGLSEPSPPSAYQK 22830
Query: 1170 VVTPL---SPPTNLHLEANPDTGVLTVSWERSTTP---DITGYRITTTPTNGQQGNSLEE 1223
P+ PP N + + V +SW + +I GY + + +
Sbjct: 22831 ACDPIYKPGPPNNPKVIDITRSSVF-LSWSKPIYDGGCEIQGYIVEKCDVSVGEWTMCTP 22889
Query: 1224 VVHADQSSCTFDNLSPGLEYNVSVYTVKD----DKESVPISDTIIPEVPQLTDLSFVDIT 1279
++++ + L EYN + + + VP I+ E + D+
Sbjct: 22890 PTGINKTNIEVEKLLEKHEYNFRICAINKAGVGEHADVP-GPIIVEEKLEAPDI------ 22942
Query: 1280 DSSIGLRWTPLNSSTIIGYRITVVAAGEGIP----------IFEDFVDSSVGYYTVTGLE 1329
D + LR +N R+ V G P I + + +T L+
Sbjct: 22943 DLDLELRKI-INIRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTSSFTSLVLD 23001
Query: 1330 PGIDYDISVITLI----NGGESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAPPPSID 1385
YD TL +G +SA T+ PP +L+ T I D++ +TW PP +D
Sbjct: 23002 NVNRYDSGKYTLTLENSSGTKSAFVTVRVLDTPSPPVNLKVTEITKDSVSITW-EPPLLD 23060
Query: 1386 LTNFLVRYSPVKNE---EDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLR 1442
+ + Y K E + A + + N+ + L G Y V++ E P +
Sbjct: 23061 GGSKIKNYIVEKREATRKSYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAENEYGIGLPAQ 23120
Query: 1443 GRQKTGL----DSPTGIDFSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPRE 1494
+ P I D+T NS ++ W P + I Y + +H
Sbjct: 23121 TADPIKVAEVPQPPGKITVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKHSEKWSEC 23180
Query: 1495 DRVPHSRNSITLTNLTPGTEYVVSIVALNGREES-PLLIGQQSTVSDVPRDLEVVAA-TP 1552
RV + +TNLT G EY+ +VA+N + S P + D+ + +V A +
Sbjct: 23181 ARVKSLQ--AVITNLTQGEEYLFRVVAVNEKGRSDPRSLAVPIVAKDLVIEPDVKPAFSS 23238
Query: 1553 TSLLISWD----APAVTVRYYRITYGETGGNSPVQEFT---VPGSKSTATIS----GLKP 1601
S+ + D P IT+ + G P+++ T V S T+S
Sbjct: 23239 YSVQVGQDLKIEVPISGRPKPTITWTKDG--LPLKQTTRINVTDSLDLTTLSIKETHKDD 23296
Query: 1602 GVDYTITVYAVTGRGDSPASSKPISINYRTEIDKP----SQMQVTDVQDNSISVKWLP-- 1655
G Y ITV V G+ K SI T +DKP ++ DV SI++ W P
Sbjct: 23297 GGQYGITVANVVGQ-------KTASIEIVT-LDKPDPPKGPVKFDDVSAESITLSWNPPL 23348
Query: 1656 --SSSPVTGYRV-----TTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNP 1708
+T Y V TTT + T +T + + L+ EY ++A+N
Sbjct: 23349 YTGGCQITNYIVQKRDTTTTVWDVVSATVARTT------LKVTKLKTGTEYQFRIFAENR 23402
Query: 1709 SG-----ESQPLVQTAVTNIDRPKGLAF-TDVDVDSIKIAWESPQGQVSRYRVTYSSPED 1762
G ES P+V P G F T + DS+ I W P + Y
Sbjct: 23403 YGQSFALESDPIVAQYPYKEPGPPGTPFATAISKDSMVIQWHEPVNNGGSPVIGYHLERK 23462
Query: 1763 GIHELFPAPDGE---EDTA-ELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTD 1818
+ + + DT + Q L G EY V A + + ++ P D
Sbjct: 23463 ERNSILWTKVNKTIIHDTQFKAQNLEEGIEYEFRVYAENIVGVGKASKNSECYVARDPCD 23522
Query: 1819 LKFT----QVTPTSLSAQWTPP----NVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVV 1870
T V ++ QWT P +TGY V MK + V
Sbjct: 23523 PPGTPEPIMVKRNEITLQWTKPVYDGGSMITGYIVEKRDLPDGRWMKASFTNVIETQFTV 23582
Query: 1871 SGLMVATKYEVSVYALKDT-LTSRPAQ--GVVTTLENVSPPRRARVTDATETTITISWRT 1927
SGL +YE V A S+P+ G +T + V PR + +T + + T
Sbjct: 23583 SGLTEDQRYEFRVIAKNAAGAISKPSDSTGPITAKDEVELPRISMDPKFRDTIVVNAGET 23642
Query: 1928 KTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQ-PGTDYKIYL------------ 1974
F+++A P ++ D + TD+K L
Sbjct: 23643 -------FRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRIDGGQ 23695
Query: 1975 YTLNDN----ARSSPV---VIDASTAIDAPSNLRFLATTPNSLLVSWQPP----RARITG 2023
Y L + ++S PV V+D + P ++ T ++W PP + I+
Sbjct: 23696 YILRASNVAGSKSFPVNVKVLDRPGPPEGP--VQVTGVTSEKCSLTWSPPLQDGGSDISH 23753
Query: 2024 YIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTD 2083
Y+++ ++ S V +T L G EY ++A+ EPL +
Sbjct: 23754 YVVE-KRETSRLAWTVVASEVVTNSLKVTKLLEGNEYVFRIMAVNKYGVGEPL------E 23806
Query: 2084 ELPQLVTLPHPNLHGPEILDVPSTVQKTPFVTHPGYDTGNGIQLPG 2129
P L+ P P+ L+V + + + V D+ G ++ G
Sbjct: 23807 SAPVLMKNPFVLPGPPKSLEVTNIAKDSMTVCWNRPDSDGGSEIIG 23852
Score = 86.7 bits (213), Expect = 3e-16
Identities = 349/1678 (20%), Positives = 599/1678 (35%), Gaps = 279/1678 (16%)
Query: 628 IQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISI 684
+ W+ P+ S I+ +I+ R + W++ I + I GL G Y+ ++I+
Sbjct: 15215 LNWSDPEDDGGSEITGFIIE-RKDAKMHTWRQP-IETERSKCDITGLLEGQEYKFRVIAK 15272
Query: 685 QQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWV--- 741
++G PV + P + TE T S+ + W
Sbjct: 15273 NKFG-------------CGPPVEIGPILAVDPLGPPTSPERLTYTERTKSTITLDWKEPR 15319
Query: 742 -SASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQS 800
+ + G+ +E ++ D + TS + +L + Y V ++E GE
Sbjct: 15320 SNGGSPIQGYIIEKRRHDKPDFERVNKRLCPTTSFLVENLDEHQMYEFRVKAVNEIGESE 15379
Query: 801 LILSTSQTTAPDAPPDPTVD---QVDDTSIVVRWSRP---QAPITGYRIVYSPSVEGSST 854
L + D P PT+ V +I V+ P A +TG + P +E S
Sbjct: 15380 PSLPLNVVIQDDEVP-PTIKLRLSVRGDTIKVKAGEPVHIPADVTGLPM---PKIEWSKN 15435
Query: 855 E--LNLPETANSVTLSDLQPG-VQYNITI-YAVEENQESTPVVIQQETTGTPRS------ 904
E + P A +T ++ + ++I AV E++ + V R+
Sbjct: 15436 ETVIEKPTDALQITKEEVSRSEAKTELSIPKAVREDKGTYTVTASNRLGSVFRNVHVEVY 15495
Query: 905 DTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPGEHGQRLPISRNT 960
D PR+L ++ + W P S +T Y +D + + + NT
Sbjct: 15496 DRPSPPRNLAVTDIKAESCYLTWDAPLDNGGSEITHYVIDKRDASRKKAEWEEVT---NT 15552
Query: 961 FAE----VTGLSPGVTYYFKV-----FAVSHGRESKPLTAQQTTKLDAPTNL-QFVNETD 1010
E + L P Y F+V + +S +S + Q +L P + + T
Sbjct: 15553 AVEKRYGIWKLIPNGQYEFRVRAVNKYGISDECKSDKVVIQDPYRLPGPPGKPKVLARTK 15612
Query: 1011 STVLVRWTPPR----AQITGYRLTVGLTRRGQPRQY----------NVGPSVSKYPLRNL 1056
++LV WTPP + ITGY L +R + Y VG ++ + L
Sbjct: 15613 GSMLVSWTPPLDNGGSPITGY----WLEKREEGSPYWSRVSRAPITKVGLKGVEFNVPRL 15668
Query: 1057 QPASEYTVSLVAIKG-------NQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTP 1109
+Y +AI P+ G PG P + T+++I + W P
Sbjct: 15669 LEGVKYQFRAMAINAAGIGPPSEPSDPEVAGD-PIFPPGPPSCPEVKDKTKSSISLGWKP 15727
Query: 1110 APRIGFKLGVRPSQGG--EAPREVTSDSGSI------------VVSGLTPGVEYVYTIQV 1155
K G P +G E E T+D + VV L +Y + ++
Sbjct: 15728 PA----KDGGSPIKGYIVEMQEEGTTDWKRVNEPDKLITTCECVVPNLKELRKYRFRVKA 15783
Query: 1156 LRD-GQERDAPIVNKV-VTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPT 1213
+ + G+ + ++ T + + ++ ++ + + P + R T +
Sbjct: 15784 VNEAGESEPSDTTGEIPATDIQEEPEVFIDIGAQDCLVCKAGSQIRIPAVIKGRPTPKSS 15843
Query: 1214 ---NGQQGNSLEEVVH---ADQSSCTFDNLSPGL----------EYNVSVYTVKDDKES- 1256
+G+ ++++ VH D T +N S + +Y+++ K +
Sbjct: 15844 WEFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECKRSHTGKYSITAKNKAGQKTAN 15903
Query: 1257 --VPISDTIIPEVPQLTDLSFVDITDSSIGLRWTPLNSS---TIIGYRITVVAAGEGIPI 1311
V + D +P P+ DL DIT S L W + I GY I +G
Sbjct: 15904 CRVKVMD--VPGPPK--DLKVSDITRGSCRLSWKMPDDDGGDRIKGYVIEKRTI-DGKAW 15958
Query: 1312 FEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAV-------PPPTDL 1364
+ D + V L Y V G P Q+T PP L
Sbjct: 15959 TKVNPDCGSTTFVVPDLLSEQQYFFRVRAENRFGIGPPVETIQRTTARDPIYPPDPPIKL 16018
Query: 1365 RFTNIGPDTMRVTWAPPPS---IDLTNFLVR---YSPVK---------NEEDVAELSISP 1409
+ I +T+ ++W PP + +T+++V + P N+ DV EL +
Sbjct: 16019 KIGLITKNTVHLSWKPPKNDGGSPVTHYIVECLAWDPTGTKKEAWRQCNKRDVEELQFTV 16078
Query: 1410 SDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGL---DSPTGIDFSDI--TANS 1464
D L+ G EY V +V S P D P ID +
Sbjct: 16079 ED-------LVEGGEYEFRVKAVNAAGVSKPSATVGPCDCQRPDMPPSIDLKEFMEVEEG 16131
Query: 1465 FTVHWIA-----PRATITGYRIRH----------HPEHFSGRPREDR----VPHSRNSIT 1505
V+ +A P T+T ++ + H + +D +P SR S T
Sbjct: 16132 TNVNIVAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDT 16191
Query: 1506 LTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAP--- 1562
Y ++ V G + + ++ + + + +SW P
Sbjct: 16192 GL-------YTITAVNNLGTASKEMRLNVLGRPGPPVGPIKFESVSADQMTLSWFPPKDD 16244
Query: 1563 -AVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRG-DSPA 1620
+ Y I E + V + P + T TI L G +Y + A G P
Sbjct: 16245 GGSKITNYVIEKREANRKTWVHVSSEP-KECTYTIPKLLEGHEYVFRIMAQNKYGIGEPL 16303
Query: 1621 SSKPISI-NYRTEIDKPSQMQVTDVQDNSISVKW----LPSSSPVTGYRVT---TTPKN- 1671
S+P + N + P + V+ V NS++V W SPVTGY + TT K
Sbjct: 16304 DSEPETARNLFSVPGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPVTGYWLEMKDTTSKRW 16363
Query: 1672 ---GPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSG---ESQPLVQTAVTNIDR 1725
P K T G + GL +Y VYA N +G S P +
Sbjct: 16364 KRVNRDPIKAMTLG---VSYKVTGLIEGSDYQFRVYAINAAGVGPASLPSDPATARDPIA 16420
Query: 1726 PKGLAF---TDVDVDSIKIAWESPQ----GQVSRYRVTYSSPEDGIHELFPAPDGEEDTA 1778
P G F TD S + W P +V+ Y V Y E+G E D E
Sbjct: 16421 PPGPPFPKVTDWTKSSADLEWSPPLKDGGSKVTGYIVEYK--EEGKEEWEKGKDKEVRGT 16478
Query: 1779 EL--QGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPT-SLSAQWTP 1835
+L GL+ G+ Y V A++ +P G + I ++K V+P L A
Sbjct: 16479 KLVVTGLKEGAFYKFRVRAVNIAGIGEP--GEVTDVI----EMKDRLVSPDLQLDASVRD 16532
Query: 1836 PNVQLTGYRVRVT-------PKEKTGPMKEINLAPDSS--SVVVSGLMVATKYEVS---V 1883
V G +R+ P T M E L +++ + +S MV + S V
Sbjct: 16533 RIVVHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEATIETTAISSSMVIKNCQRSHQGV 16592
Query: 1884 YAL--KDTLTSRPAQGVVTTLENVSPPRRARVT-DATETTITISWRTKTET----ITGFQ 1936
Y+L K+ R +V L+ P + + T + ++W + + IT +
Sbjct: 16593 YSLLAKNEAGERKKTIIVDVLDVPGPVGTPFLAHNLTNESCKLTWFSPEDDGGSPITNYV 16652
Query: 1937 VDAVPANGQ--TPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLND-------NARSSPVV 1987
++ ++ + TP+ T+ ++ T+ GL G Y + N + V+
Sbjct: 16653 IEKRESDRRAWTPVTYTVTR--QNATVQGLIQGKAYFFRIAAENSIGMGPFVETSEALVI 16710
Query: 1988 IDASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREVVPRPR 2043
+ T + P +L T N++ ++W PP+ + I Y+++ G+ V
Sbjct: 16711 REPITVPERPEDLEVKEVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEKFHKVTNDN 16770
Query: 2044 PGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELPQLVT----LPHPNLH 2097
+ T+ GL+ G Y V A+ ++G+ K + +T L P LH
Sbjct: 16771 LLSRKYTVKGLKEGDTYEYRVSAVN-------IVGQGKPSFCTKPITCKDELAPPTLH 16821
Score = 86.7 bits (213), Expect = 3e-16
Identities = 320/1612 (19%), Positives = 550/1612 (34%), Gaps = 233/1612 (14%)
Query: 630 WNAPQPSH---ISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQ 686
W+ P+ IS Y++ R +S W E +Y L G+ Y+ ++ + +
Sbjct: 21180 WDPPENDGGVPISNYVVEMRQTDST-TWVELATTVIRTTYKATRLTTGLEYQFRVKAQNR 21238
Query: 687 YGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSW----VS 742
YG +TS + P + VT +T S +SW
Sbjct: 21239 YG-------------VGPGITSACIVANYPFKVPGPPGTPQVTAVTKDSMTISWHEPLSD 21285
Query: 743 ASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNI---PDLLPGRKYIVNVYQISEDGEQ 799
+ G+ VE +E + + + NI L G Y V + G+
Sbjct: 21286 GGSPILGYHVE---RKERNGILWQTVSKALVPGNIFKSSGLTDGIAYEFRVIAENMAGKS 21342
Query: 800 SLILSTSQTTAPDA---PPDPTVDQVDDTSIVVRWSRPQAP----ITGYRIVYSPSVEGS 852
+ A D P P + ++ ++W++P+ IT Y + G
Sbjct: 21343 KPSKPSEPMLALDPIDPPGKPVPLNITRHTVTLKWAKPEYTGGFKITSYIVEKRDLPNGR 21402
Query: 853 STELNLPETA-NSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPR 911
+ N N T+S L Y + A +P + + D V +P+
Sbjct: 21403 WLKANFSNILENEFTVSGLTEDAAYEFRVIAKNAAGAISPP--SEPSDAITCRDDVEAPK 21460
Query: 912 ---DLQFVEVTDVKV----------------TIMWTPPESAVTG-----YRVDVIPVNLP 947
D++F + +K T+ W+ + G ++ NL
Sbjct: 21461 IKVDVKFKDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLV 21520
Query: 948 GEHGQRLPISRNTFAEVTGLSPG--VTYYFKVFAVSH-GRESKPLTAQQTTKLDAPTNLQ 1004
+ R T +T +PG + F V + G PL + T
Sbjct: 21521 NKDSTRRDSGAYT---LTATNPGGFAKHIFNVKVLDRPGPPEGPLAVTEVTS-------- 21569
Query: 1005 FVNETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPAS 1060
++ W PP A+I Y + T R V+K + L +
Sbjct: 21570 ------EKCVLSWFPPLDDGGAKIDHYIVQKRETSRLAWTNVASEVQVTKLKVTKLLKGN 21623
Query: 1061 EYTVSLVAIK--GNQESPKATGVFTTLQPGSSIPPYNTEVTETT---IVITWTPAPRIGF 1115
EY ++A+ G E ++ V G PP N EVT T +V+ W G
Sbjct: 21624 EYIFRVMAVNKYGVGEPLESEPVLAVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGG 21683
Query: 1116 K-----LGVRPSQGGEAPREVTSDSGSIV-----VSGLTPGVEYVYTIQVLR----DGQE 1161
+ R + G+ R + + ++ VSGLT G EY + I
Sbjct: 21684 SEIINYIVERRDKAGQ--RWIKCNKKTLTDLRYKVSGLTEGHEYEFRIMAENAAGISAPS 21741
Query: 1162 RDAPIVNKVVTPLSP-PTNLHLEANPDTGVLTVSWERSTTP---DITGYRITTTPTNGQQ 1217
+P T P P + ++++W + +ITGY + +
Sbjct: 21742 PTSPFYKACDTVFKPGPPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIALPEEDE 21801
Query: 1218 GNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPEVPQLTDLSFVD 1277
+ +S T L+ EY + +Y + + P ++P P+ D
Sbjct: 21802 WQIVTPPAGLKATSYTITGLTENQEYKIRIYAMNSEGLGEP---ALVPGTPKAEDRMLPP 21858
Query: 1278 ITDSSIGLRWTPLNSSTIIGYRITVVAAGEGIP-----------IFEDFVDSSVGY-YTV 1325
+ LR + R+ V G P + + ++S+ Y +
Sbjct: 21859 EIELDADLRKV-VTIRACCTLRLFVPIKGRPAPEVKWARDHGESLDKASIESTSSYTLLI 21917
Query: 1326 TGLEPGIDYDISVITLIN--GGESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAPPPS 1383
G D ++T+ N G +SA + PP DL+ + ++ +TW PP
Sbjct: 21918 VGNVNRFDSGKYILTVENSSGSKSAFVNVRVLDTPGPPQDLKVKEVTKTSVTLTW-DPPL 21976
Query: 1384 IDLTNFLVRYSPVKNEEDVAELSISPSD---NAVVLTNLLPGTEYVVSVSSVYEQHESTP 1440
+D + + Y K E S ++ + + L G Y V + E P
Sbjct: 21977 LDGGSKIKNYIVEKRESTRKAYSTVATNCHKTSWKVDQLQEGCSYYFRVLAENEYGIGLP 22036
Query: 1441 LRGRQKTGLDS----PTGIDFSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRP 1492
+ P I D+T NS ++ W P + I GY + +
Sbjct: 22037 AETAESVKASERPLPPGKITLMDVTRNSVSLSWEKPEHDGGSRILGYIVEMQTKGSDKWA 22096
Query: 1493 REDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAA-- 1550
V + T+T L G EY + A N E + +Q +V + +DL + A
Sbjct: 22097 TCATVKVTE--ATITGLIQGEEYSFRVSAQN---EKGISDPRQLSVPVIAKDLVIPPAFK 22151
Query: 1551 ----TPTSLL---ISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGL--KP 1601
T T L + D P + +T+ + N P+++ T ++ST S L K
Sbjct: 22152 LLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKD--NVPLKQTTRVNAESTENNSLLTIKD 22209
Query: 1602 GVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQ----MQVTDVQDNSISVKWLP-- 1655
+ Y V + + + +++ +DKP +++ +V +SI++ W P
Sbjct: 22210 ACREDVGHYVVKLTNSAGEAIETLNV---IVLDKPGPPTGPVKMDEVTADSITLSWGPPK 22266
Query: 1656 --SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEG--LQPTVEYVVSVYAQNPSGE 1711
S + Y V K T + TI+ L+ EY + A+N G+
Sbjct: 22267 YDGGSSINNYIVE---KRDTSTTTWQIVSATVARTTIKACRLKTGCEYQFRIAAENRYGK 22323
Query: 1712 S-----QPLVQTAVTNIDRPKGLAFTDVDV-DSIKIAWESPQGQVSRYRVTYSSPEDGIH 1765
S +P V + P G + DS+++ W P + Y +
Sbjct: 22324 STYLNSEPTVAQYPFKVPGPPGTPVVTLSSRDSMEVQWNEPISDGGSRVIGYHLERKERN 22383
Query: 1766 ELF-------PAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTD 1818
+ P P + T GL G EY V A + +P ++ P D
Sbjct: 22384 SILWVKLNKTPIPQTKFKTT---GLEEGVEYEFRVSAENIVGIGKPSKVSECYVARDPCD 22440
Query: 1819 L----KFTQVTPTSLSAQWTPPNV----QLTGYRVRVTPKEKTGPMKEINLAPDSSSVVV 1870
+ VT S++ QW P ++TGY V + MK + V
Sbjct: 22441 PPGRPEAIIVTRNSVTLQWKKPTYDGGSKITGYIVEKKELPEGRWMKASFTNIIDTHFEV 22500
Query: 1871 SGLMVATKYEVSVYALKDT-LTSRPAQ--GVVTTLENVSPPRRARVTDATETTITISWRT 1927
+GL+ +YE V A + S P++ G +T + V PPR + +T + + +
Sbjct: 22501 TGLVEDHRYEFRVIARNAAGVFSEPSESTGAITARDEVDPPRISMDPKYKDTIVVHAGES 22560
Query: 1928 KTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQ-PGTDYKIYLYTLNDNAR--SS 1984
F+VDA P + IK D L+ TD+ L ++ D R S
Sbjct: 22561 -------FKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSL-SVKDAVRVDSG 22612
Query: 1985 PVVIDASTAIDAPS---NLRFL-------------ATTPNSLLVSWQPPR----ARITGY 2024
++ A S N++ L T ++W+PP + I Y
Sbjct: 22613 NYILKAKNVAGERSVTVNVKVLDRPGPPEGPVVISGVTAEKCTLAWKPPLQDGGSDIINY 22672
Query: 2025 IIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPL 2076
I++ + VV +T L G EYT ++A+ EPL
Sbjct: 22673 IVERRETSRLVWTVVDA-NVQTLSCKVTKLLEGNEYTFRIMAVNKYGVGEPL 22723
Score = 86.3 bits (212), Expect = 3e-16
Identities = 362/1829 (19%), Positives = 635/1829 (34%), Gaps = 273/1829 (14%)
Query: 628 IQWNAPQPS---HISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISI 684
+ WN P + I+ YI++ R + W + + + LK G Y+ ++ +
Sbjct: 23342 LSWNPPLYTGGCQITNYIVQKRDTTTTV-WDVVSATVARTTLKVTKLKTGTEYQFRIFAE 23400
Query: 685 QQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSAS 744
+YG D P+ + E P AT+ I+ S V+ W
Sbjct: 23401 NRYGQSFALESD--------PIVAQYPYKEPGPPGTPFATA-----ISKDSMVIQWHEPV 23447
Query: 745 DTVSGFRVEYELS-EEGDEPQYLDLPSTA---TSVNIPDLLPG-----RKYIVNVYQISE 795
+ + Y L +E + + + T T +L G R Y N+ + +
Sbjct: 23448 NNGGSPVIGYHLERKERNSILWTKVNKTIIHDTQFKAQNLEEGIEYEFRVYAENIVGVGK 23507
Query: 796 DGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ----APITGYRIVYSPSVEG 851
+ S P P+P + V I ++W++P + ITGY + +G
Sbjct: 23508 ASKNSECYVARDPCDPPGTPEPIM--VKRNEITLQWTKPVYDGGSMITGYIVEKRDLPDG 23565
Query: 852 ---SSTELNLPETANSVTLSDLQPGVQYNITIYA------VEENQESTPVVIQQETTGTP 902
++ N+ ET T+S L +Y + A + + +ST + ++ P
Sbjct: 23566 RWMKASFTNVIET--QFTVSGLTEDQRYEFRVIAKNAAGAISKPSDSTGPITAKDEVELP 23623
Query: 903 RSDTVPSPRDLQFVEVTDV-----------KVTIMWTPPESAVTGYRVDVIPVNLPGEHG 951
R P RD V + TI W + + E
Sbjct: 23624 RISMDPKFRDTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEI--------------EES 23669
Query: 952 QRLPISRNTFAEVTGLSPGVT-----YYFKVFAVSHGRESKPLTAQQTTKLDAPTN-LQF 1005
R I F + + + Y + V+ G +S P+ + + P +Q
Sbjct: 23670 ARCEIKNTDFKALLIVKDAIRIDGGQYILRASNVA-GSKSFPVNVKVLDRPGPPEGPVQV 23728
Query: 1006 VNETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASE 1061
T + W+PP + I+ Y + T R + + L +E
Sbjct: 23729 TGVTSEKCSLTWSPPLQDGGSDISHYVVEKRETSRLAWTVVASEVVTNSLKVTKLLEGNE 23788
Query: 1062 YTVSLVAIK--GNQESPKATGVFTT---LQPGSSIPPYNTEVT---ETTIVITWTPAPR- 1112
Y ++A+ G E ++ V + PG PP + EVT + ++ + W
Sbjct: 23789 YVFRIMAVNKYGVGEPLESAPVLMKNPFVLPG---PPKSLEVTNIAKDSMTVCWNRPDSD 23845
Query: 1113 -----IGFKLGVRPSQGGE----APREVTSDSGSIVVSGLTPGVEYVYTIQVLRD---GQ 1160
IG+ + R G R +T + V+GLT EY + + G+
Sbjct: 23846 GGSEIIGYIVEKRDRSGIRWIKCNKRRITDLR--LRVTGLTEDHEYEFRVSAENAAGVGE 23903
Query: 1161 ERDAPIVNKVVTPL---SPPTNLHLEANPDTGVLTVSWERSTTP---DITGYRITTTPTN 1214
A + K P+ PPTN H+ + +T++W + +I GY + +
Sbjct: 23904 PSPATVYYKACDPVFKPGPPTNAHI-VDTTKNSITLAWGKPIYDGGSEILGYVVEICKAD 23962
Query: 1215 GQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDK--ESVPISDTIIPE----VP 1268
++ + + L+ EY + V + E+ + T+ PE P
Sbjct: 23963 EEEWQIVTPQTGLRVTRFEISKLTEHQEYKIRVCALNKVGLGEATSVPGTVKPEDKLEAP 24022
Query: 1269 QLTDLSFVDITDSSIGLRWTPLNSSTII--GYRITVVAAGEGIPIFEDFVDSSVGYYT-V 1325
+L DL + L ++ G + +G P E G +T
Sbjct: 24023 EL-DLD-------------SELRKGIVVRAGGSARIHIPFKGRPTPEITWSREEGEFTDK 24068
Query: 1326 TGLEPGIDYD---------------ISVITLINGGESAPTTLTQQTAVPPPTDLRFTNIG 1370
+E G++Y I + +G +SA T+ PP +L +
Sbjct: 24069 VQIEKGVNYTQLSIDNCDRNDAGKYILKLENSSGSKSAFVTVKVLDTPGPPQNLAVKEVR 24128
Query: 1371 PDTMRVTWAPPPSIDLTNFLVRYSPVKNEED---VAELSISPSDNAVVLTNLLPGTEYVV 1427
D+ + W PP ID + Y K E A +S S + + NL G Y
Sbjct: 24129 KDSAFLVWEPP-IIDGGAKVKNYVIDKRESTRKAYANVSSKCSKTSFKVENLTEGAIYYF 24187
Query: 1428 SVSSVYEQHESTPLR---GRQKTGLDSPTG-IDFSDITANSFTVHWIAPR----ATITGY 1479
V + E P+ + SP G + +D++ S ++ W P + + GY
Sbjct: 24188 RVMAENEFGVGVPVETVDAVKAAEPPSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLGY 24247
Query: 1480 RIRHHPEHFSGRPREDRVPHSRN-SITLTNLTPGTEYVVSIVALNGREES-PLLIGQQST 1537
+ P+ G + V S+ + +T L+ G EY + A N + +S P ++G
Sbjct: 24248 VVEMQPK---GTEKWSIVAESKVCNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVI 24304
Query: 1538 VSDVPRDLEVVAATPTSLL-----ISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKS 1592
D+ + T + + + P + I++ + G P+++ T +
Sbjct: 24305 AKDLTIQPSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDG--EPLKQTTRVNVEE 24362
Query: 1593 TAT--ISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKP-SQMQVTDVQDNSI 1649
TAT + +K G Y VT + +++ +S+ + P ++ +V + +
Sbjct: 24363 TATSTVLHIKEGNKDDFGKYTVTATNSAGTATENLSVIVLEKPGPPVGPVRFDEVSADFV 24422
Query: 1650 SVKWLPSS----SPVTGYRV-----TTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYV 1700
+ W P + ++ Y V TTT + T +T + I L+ EY
Sbjct: 24423 VISWEPPAYTGGCQISNYIVEKRDTTTTTWHMVSATVARTT------IKITKLKTGTEYQ 24476
Query: 1701 VSVYAQNPSGESQPLVQTAVT-----NIDRPKGLAF-TDVDVDSIKIAWESPQGQVSRYR 1754
++A+N G+S PL AV P G F T + D + + W P
Sbjct: 24477 FRIFAENRYGKSAPLDSKAVIVQYPFKEPGPPGTPFVTSISKDQMLVQWHEPVNDGGTKI 24536
Query: 1755 VTYSSPEDGIHELF-------PAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIG 1807
+ Y + + + P D + T GL G EY V A + +P
Sbjct: 24537 IGYHLEQKEKNSILWVKLNKTPIQDTKFKTT---GLDEGLEYEFKVSAENIVGIGKPSKV 24593
Query: 1808 TQSTAIPAPTD----LKFTQVTPTSLSAQWTPP----NVQLTGYRVRVTPKEKTGPMKEI 1859
++ P D + +T +++ +W P ++TGY V MK
Sbjct: 24594 SECFVARDPCDPPGRPEAIVITRNNVTLKWKKPAYDGGSKITGYIVEKKDLPDGRWMKAS 24653
Query: 1860 NLAPDSSSVVVSGLMVATKYEVSVYALKDTLT-SRP--AQGVVTTLENVSPPRRAR---- 1912
+ VSGL+ +YE V A S P + G +T + + P +
Sbjct: 24654 FTNVLETEFTVSGLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARDEIDAPNASLDPKY 24713
Query: 1913 ----VTDATET-TITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQ-P 1966
V A ET + R K + D +T + IK ++ T+
Sbjct: 24714 KDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELE-ETAARMEIKSTIQKTTLVVKDCI 24772
Query: 1967 GTDYKIYLYTLND--NARSSPVVIDASTAIDAPSN-LRFLATTPNSLLVSWQPP----RA 2019
TD Y+ L++ +S P+ + P L+ T ++W PP A
Sbjct: 24773 RTDGGQYILKLSNVGGTKSIPITVKVLDRPGPPEGPLKVTGVTAEKCYLAWNPPLQDGGA 24832
Query: 2020 RITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGR 2079
I+ YII+ + V + +T L PG EY V+A+ EPL
Sbjct: 24833 NISHYIIEKRETSRLSWTQVSTEVQAL-NYKVTKLLPGNEYIFRVMAVNKYGIGEPL--- 24888
Query: 2080 KKTDELPQLVTLPHPNLHGPEILDVPSTVQKTPFVTHPGYDTGNGIQLPGTSGQQPSVGQ 2139
+ P P+ P +V + + + VT G ++ G ++
Sbjct: 24889 ---ESGPVTACNPYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILEKR---- 24941
Query: 2140 QMIFEEHGFRRT-TPPTTATPIRHR------PRPYPPNVGEE--IQIGHIPREDVDYH-- 2188
++ G R T T T +R R Y V E +G V Y
Sbjct: 24942 ----DKEGVRWTKCNKKTLTDLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRAC 24997
Query: 2189 --LYPHGPGLNPNASTGQEALSQTTISWA-PFQD----TSEYIISCHPVGTDEEPLQFRV 2241
LYP GP NP + + S +++W+ P D Y++ DE
Sbjct: 24998 DALYPPGPPSNPKVT--DTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAADEWTTCTPP 25055
Query: 2242 PG-TSTSATLTGLTRGATYNIIVEALKDQ 2269
G T+T L YN + A+ +
Sbjct: 25056 TGLQGKQFTVTKLKENTEYNFRICAINSE 25084
Score = 84.3 bits (207), Expect = 1e-15
Identities = 263/1195 (22%), Positives = 417/1195 (34%), Gaps = 139/1195 (11%)
Query: 624 NSHPIQWNAPQ---PSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQ 680
N+ + WN P+ S I Y+L R + K YT+KGLK G YE +
Sbjct: 16731 NTVTLTWNPPKYDGGSEIINYVLESRLIGTEKFHKVTNDNLLSRKYTVKGLKEGDTYEYR 16790
Query: 681 LISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSW 740
+ ++ G + + + P+T E P + + + +T +F ++
Sbjct: 16791 VSAVNIVGQGK-------PSFCTKPITCK---DELAPPTLHLDFRDKLTIRVGEAFALTG 16840
Query: 741 ---VSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNI-PDLLPGRKYIVNVYQISED 796
VS F+ E ++ E+ D P+T I KY V V +
Sbjct: 16841 RYSGKPKPKVSWFKDEADVLED-DRTHIKTTPATLALEKIKAKRSDSGKYCVVVE--NST 16897
Query: 797 GEQSLILSTSQTTAPDAPPDP-TVDQVDDTSIVVRWSRP----QAPITGYRIVYSPSVEG 851
G + + P P P + D+V +V+ W P + IT Y I +
Sbjct: 16898 GSRKGFCQVNVVDRPGPPVGPVSFDEVTKDYMVISWKPPLDDGGSKITNYIIEKKEVGKD 16957
Query: 852 SSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPR 911
+ + +S L G Y I+A S P+V ++ VP
Sbjct: 16958 VWMPVTSASAKTTCKVSKLLEGKDYIFRIHAENLYGISDPLV--SDSMKAKDRFRVPDAP 17015
Query: 912 DLQFV-EVTDVKVTIMWTPPESA---VTGYRVDV-IPVNLPGEHGQRLPISRNTFAEVTG 966
D V EVT + W P +T Y ++ ++ + PI T V
Sbjct: 17016 DQPIVTEVTKDSALVTWNKPHDGGKPITNYILEKRETMSKRWARVTKDPIHPYTKFRVPD 17075
Query: 967 LSPGVTYYFKVFAVSH------GRESKPLTAQQ-TTKLDAPTNLQFVNETDSTVLVRWTP 1019
L G Y F+V A + SKP+ A+ K P N + ++ T ++V + W P
Sbjct: 17076 LLEGCQYEFRVSAENEIGIGDPSPPSKPVFAKDPIAKPSPPVNPEAIDTTCNSVDLTWQP 17135
Query: 1020 PR----AQITGYRLTVGLTRRGQPRQYNVGPS---VSKYPLRNLQPASEYTVSLVAIKGN 1072
PR ++I GY + + R+ N P +KY + L+ Y ++A+
Sbjct: 17136 PRHDGGSKILGYIVEYQKVGDEEWRRANHTPESCPETKYKVTGLRDGQTYKFRVLAVNAA 17195
Query: 1073 QES-----PKATGVFTTLQPGSSIPPYNT---------EVTETTIVITWTPAPRIGFKLG 1118
ES P+ V L+P I N + + +I P P++ +K
Sbjct: 17196 GESDPAHVPEPVLVKDRLEPPELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKE 17255
Query: 1119 VRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPT 1178
R + +A +VT + + +Y++ V + + V+ PP
Sbjct: 17256 DRDAP-TKARIDVTPVGSKLEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDKPGPPR 17314
Query: 1179 NLHL-EANPDTGVLTVSWERSTTPD---ITGYRITTTPTNGQQGNSLEEVVHADQSSCTF 1234
+L + E D+ LT W+ IT Y + Q + L + + S
Sbjct: 17315 DLEVSEIRKDSCYLT--WKEPLDDGGSVITNYVVERRDVASAQWSPLSAT--SKKKSHFA 17370
Query: 1235 DNLSPGLEYNVSVYTVK--------DDKESVPISDTIIPEVPQLTDLSFVDITDSSIGLR 1286
+L+ G +Y V + + + D + P P DL VD+ + + L
Sbjct: 17371 KHLNEGNQYLFRVAAENQYGRGPFVETPKPIKALDPLHPPGPP-KDLHHVDVDKTEVSLV 17429
Query: 1287 WTPLN---SSTIIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLIN 1343
W + S I GY V EG + F + VTGL+ G Y V
Sbjct: 17430 WNKPDRDGGSPITGY--LVEYQEEGTQDWIKFKTVTNLECVVTGLQQGKTYRFRVKAENI 17487
Query: 1344 GGESAPTTL----TQQTAVPPPTDLRFTNI------GPDTMR----VTWAPPPSIDLTNF 1389
G P T Q+ VPP +L I T+R + P P+ T
Sbjct: 17488 VGLGLPDTTIPIECQEKLVPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWT-- 17545
Query: 1390 LVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGT-EYVVSVSSVYEQHESTPLRGRQKTG 1448
S +K +E + + S + L T EY ++VS+ + T
Sbjct: 17546 -TDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEYQITVSNA----AGSKTVAVHLTV 17600
Query: 1449 LD---SPTG-IDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSI 1504
LD PTG I+ D+T T+ W P+ I + E R V S +S
Sbjct: 17601 LDVPGPPTGPINILDVTPEHMTISWQPPKDDGGSPVINYIVEKQDTRKDTWGVVSSGSSK 17660
Query: 1505 T---LTNLTPGTEYVVSIVALN------GREESPLLIGQQSTVSDVPRDLEVVAATPTSL 1555
T + +L G EYV + A N + +P + + + P V T +
Sbjct: 17661 TKLKIPHLQKGCEYVFRVRAENKIGVGPPLDSTPTVAKHKFSPPSPPGKPVVTDITENAA 17720
Query: 1556 LISWDAP-----AVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVY 1610
+SW P + YY TG V + + K T GL G Y V+
Sbjct: 17721 TVSWTLPKSDGGSPITGYYMERREVTGKWVRVNKTPIADLKFRVT--GLYEGNTYEFRVF 17778
Query: 1611 AVTGRGDSPASSKPISINYRTEIDKPS---QMQVTDVQDNSISVKWL----PSSSPVTGY 1663
A G S S I I P ++ D + + W SP+ GY
Sbjct: 17779 AENLAGLSKPSPSSDPIKACRPIKPPGPPINPKLKDKSRETADLVWTKPLSDGGSPILGY 17838
Query: 1664 RVTTTPKNGPGPTKTKTAGPD----QTEMTIEGLQPTVEYVVSVYAQNPSGESQP 1714
V PG + D Q + GL EY + A N GE +P
Sbjct: 17839 VVEC---QKPGTAQWNRINKDELIRQCAFRVPGLIEGNEYRFRIKAANIVGEGEP 17890
Score = 83.2 bits (204), Expect = 3e-15
Identities = 182/840 (21%), Positives = 295/840 (35%), Gaps = 117/840 (13%)
Query: 1338 VITLIN--GGESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAPPPS---IDLTNFLVR 1392
V+T N G A T+ P +L+ ++ D V W PP ++ N+++
Sbjct: 18275 VVTATNTAGSFVAYATVNVLDKPGPVRNLKIVDVSSDRCTVCWDPPEDDGGCEIQNYILE 18334
Query: 1393 YSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQ---KTGL 1449
K + S + +T L+ G EY+ V + + P + KT
Sbjct: 18335 KCETKRMV-WSTYSATVLTPGTTVTRLIEGNEYIFRVRAENKIGTGPPTESKPVIAKTKY 18393
Query: 1450 DSPTGIDFSDITANS---FTVHWIAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRN 1502
D P D ++T S TV W P +ITGY + +H + ++
Sbjct: 18394 DKPGRPDPPEVTKVSKEEMTVVWNPPEYDGGKSITGYFLEKKEKHSTRWVPVNKSAIPER 18453
Query: 1503 SITLTNLTPGTEYVVSIVALN-------GREESPLLIGQQSTVSDVPRDLEVVAATPTSL 1555
+ + NL P EY + A N P++ P + VV T S+
Sbjct: 18454 RMKVQNLLPDHEYQFRVKAENEIGIGEPSLPSRPVVAKDPIEPPGPPTNFRVVDTTKHSI 18513
Query: 1556 LISWDAP-----AVTVRYYRITYGETGGNSPVQEFTVPGS-----KSTATISGLKPGVDY 1605
+ W P A + Y + SP + + + + T++ L +Y
Sbjct: 18514 TLGWGKPVYDGGAPIIGYVVEMRPKIADASPDEGWKRCNAAAQLVRKEFTVTSLDENQEY 18573
Query: 1606 TITVYAVTGRG-DSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYR 1664
V A G PA K E KP ++ D S++ L R
Sbjct: 18574 EFRVCAQNQVGIGRPAELK--------EAIKPKEILEPPEIDLDASMRKLVIVRAGCPIR 18625
Query: 1665 VTTTPKNGPGPTKT-KTAGPDQTEMTIE-GLQPTVEYVV------------SVYAQNPSG 1710
+ + P P T + G D + L T+ ++V S+ NP+G
Sbjct: 18626 LFAIVRGRPAPKVTWRKVGIDNVVRKGQVDLVDTMAFLVIPNSTRDDSGKYSLTLVNPAG 18685
Query: 1711 ESQPLVQTAVTNIDRP-KGLAFTDVDVDSIKIAWESPQG----QVSRYRVTYSSPEDGIH 1765
E V V + P L +DV S ++W P+ QV+ Y V +
Sbjct: 18686 EKAVFVNVRVLDTPGPVSDLKVSDVTKTSCHVSWAPPENDGGSQVTHYIVEKREADRKTW 18745
Query: 1766 ELFPAPDGEEDTAELQGLRPGSEYTVSVVALHD-------DMESQPLIGTQSTAIPAPTD 1818
P+ ++ + + L PG+EY V A+++ D+ L + P
Sbjct: 18746 STV-TPEVKKTSFHVTNLVPGNEYYFRVTAVNEYGPGVPTDVPKPVLASDPLSEPDPPRK 18804
Query: 1819 LKFTQVTPTSLSAQWTPP--------NVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVV 1870
L+ T++T S + W PP + +T YR P ++ E ++ D S +VV
Sbjct: 18805 LEVTEMTKNSATLAWLPPLRDGGAKIDGYITSYREEEQPADR---WTEYSVVKDLS-LVV 18860
Query: 1871 SGLMVATKYEVSVYALKDTLTSRP--AQGVVTTLENVSPPRRARVTDAT----------- 1917
+GL KY+ V A S P A+GV E + PP+ T
Sbjct: 18861 TGLKEGKKYKFRVAARNAVGVSLPREAEGVYEAKEQLLPPKILMPEQITIKAGKKLRIEA 18920
Query: 1918 ----ETTITISWRT-KTETITGFQVDAVPANGQTP--IQRTIKPDVRSYTITGLQPGTDY 1970
+ T W+ + E +T + A+ + I+ + D Y++T
Sbjct: 18921 HVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGYYSLTAENSSG-- 18978
Query: 1971 KIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYII 2026
D + VV+DA P ++ + SL SW P + IT YI+
Sbjct: 18979 -------TDTQKIKVVVMDAPGPPQPPFDISDIDADACSL--SWHIPLEDGGSNITNYIV 19029
Query: 2027 KYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELP 2086
+ + S V T + L PG EY V A SEPL K + P
Sbjct: 19030 E-KCDVSRGDWVTALASVTKTSCRVGKLIPGQEYIFRVRAENRFGISEPLTSPKMVAQFP 19088
Score = 80.1 bits (196), Expect = 2e-14
Identities = 310/1425 (21%), Positives = 524/1425 (36%), Gaps = 261/1425 (18%)
Query: 780 LLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPIT 839
++P ++Y++ V ++ G + A D PT+D IV+ + P+
Sbjct: 14350 VVPDKEYVLRVRAVNAIGVSEPSEISENVVAKDPDCKPTIDLETHDIIVIEGEKLSIPVP 14409
Query: 840 GYRIVYSPSV----EGSSTELNLPETANSVTLS---DLQPGVQYNITIYAV--EENQEST 890
+R V P+V +G + + T + +S ++ V+ + IY + E S
Sbjct: 14410 -FRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSA 14468
Query: 891 PVVIQQETTGTPRSDTVPSP-RDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGE 949
I + G +P P +D++ ++T + W PPE G + V E
Sbjct: 14469 TASINVKVIG------LPGPCKDIKASDITKSSCKLTWEPPE--FDGGTPILHYVLERRE 14520
Query: 950 HGQR--LPI--SRNTFA-EVTGLSPGVTYYFKVFAVSH--GRE----SKPLTAQQTTKL- 997
G+R +P+ N + V L P Y+F+V AV+ G E P+ AQ +
Sbjct: 14521 AGRRTYIPVMSGENKLSWTVKDLIPNGEYFFRVKAVNKVGGGEYIELKNPVIAQDPKQPP 14580
Query: 998 DAPTNLQFVNETDSTVLVRWTPPR----AQITGY---RLTVGLTRRGQPRQYNVGPSVSK 1050
D P +++ N T + + W PP ++I GY ++ G R + ++ V +
Sbjct: 14581 DPPVDVEVHNPTAEAMTITWKPPLYDGGSKIMGYIIEKIAKGEERWKRCNEHLV--PILT 14638
Query: 1051 YPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPA 1110
Y + L+ EY + A A G+ +P + PP T + A
Sbjct: 14639 YTAKGLEEGKEYQFRVRA-------ENAAGIS---EPSRATPP--------TKAVDPIDA 14680
Query: 1111 PRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVL--RDGQERDAPIVN 1168
P++ + + +G E + S SGS P + ++ V+ + ++R AP+V
Sbjct: 14681 PKVILRTSLEVKRGDEIALDA-SISGSPY-----PTITWIKDENVIVPEEIKKRAAPLVR 14734
Query: 1169 KVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHAD 1228
+ + L P T L++ N ++G S V
Sbjct: 14735 RRKGEVQEEEPFVL---PLTQRLSID-------------------NSKKGESQLRVR--- 14769
Query: 1229 QSSCTFDNLSPGLEYNVSVYTVKDDK--ESVPISDTIIPEVPQLTDLSFVDITDSSIGLR 1286
D+L P ++ + + V++D P + +++ + F DI +S+ +
Sbjct: 14770 ------DSLRP--DHGLYMIKVENDHGIAKAPCTVSVLDTPGPPINFVFEDIRKTSVLCK 14821
Query: 1287 WTPL---NSSTIIGYRITVVAAGEGIPIFEDFVDSSV---GYYTVTGLEPGIDYDISVIT 1340
W P S II Y T+ + P E V +S Y+VT L G +Y V
Sbjct: 14822 WEPPLDDGGSEIINY--TLEKKDKTKPDSEWIVVTSTLRHCKYSVTKLIEGKEYLFRVRA 14879
Query: 1341 LINGGESAPTTLTQQTAVPP------PTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYS 1394
G P A P P ++ ++M V W P D + ++ Y
Sbjct: 14880 ENRFGPGPPCVSKPLVAKDPFGPPDAPDKPIVEDVTSNSMLVKWNEPK--DNGSPILGYW 14937
Query: 1395 PVKNEEDVAELS-ISPSDNAVVLTN---LLPGTEYVVSVSSVYEQHESTPLR----GRQK 1446
K E + S ++ S + N LL G YV V + ++ + P + K
Sbjct: 14938 LEKREVNSTHWSRVNKSLLNALKANVDGLLEGLTYVFRVCA---ENAAGPGKFSPPSDPK 14994
Query: 1447 TGLD--SPTGIDFSDITANSFT---VHWIAPR----ATITGYRIRHHPEHFSGRPREDRV 1497
T D SP G +T S T + W P I GY + + R
Sbjct: 14995 TAHDPISPPGPPIPRVTDTSSTTIELEWEPPAFNGGGEIVGYFVDKQLVGTNEWSRCTEK 15054
Query: 1498 PHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLI 1557
T+ + G +Y + + A+N E P Q TV++ P++ A + +
Sbjct: 15055 MIKVRQYTVKEIREGADYKLRVSAVNAAGEGPPGETQPVTVAE-PQE---PPAVELDVSV 15110
Query: 1558 SWDAPAVTVRYYRITYGETGGNSPVQEFTVP--------------GSKSTATISGL--KP 1601
+ + RI TG P + +T G+KS I K
Sbjct: 15111 KGGIQIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKDRVVIDNVGTKSELIIKDALRKD 15170
Query: 1602 GVDYTITVYAVTGRGDSPA------------SSKPISINYRTEIDKPSQMQVTDVQDNSI 1649
Y IT G + A KP+ N K + +D +D+
Sbjct: 15171 HGRYVITATNSCGSKFAAARVEVFDVPGPVLDLKPVVTNR-----KMCLLNWSDPEDDG- 15224
Query: 1650 SVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPS 1709
S +TG+ + K+ T + ++++ I GL EY V A+N
Sbjct: 15225 -------GSEITGFIIER--KDAKMHTWRQPIETERSKCDITGLLEGQEYKFRVIAKNKF 15275
Query: 1710 GESQPLVQTAVTNID------RPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDG 1763
G P+ + +D P+ L +T+ +I + W+ P R SP G
Sbjct: 15276 GCGPPVEIGPILAVDPLGPPTSPERLTYTERTKSTITLDWKEP-------RSNGGSPIQG 15328
Query: 1764 I---HELFPAPDGEEDTAEL--------QGLRPGSEYTVSVVALHDDMESQPLIGTQSTA 1812
PD E L + L Y V A+++ ES+P +
Sbjct: 15329 YIIEKRRHDKPDFERVNKRLCPTTSFLVENLDEHQMYEFRVKAVNEIGESEP-------S 15381
Query: 1813 IPAPTDLKFTQVTPT---SLSAQWTPPNVQLTGYRVRVTPKEKTG-PMKEINLAPDSSSV 1868
+P ++ +V PT LS + V+ G V + P + TG PM +I + + + +
Sbjct: 15382 LPLNVVIQDDEVPPTIKLRLSVRGDTIKVK-AGEPVHI-PADVTGLPMPKIEWSKNETVI 15439
Query: 1869 VV-SGLMVATKYEVS-------------VYALKDTLTSRPAQGVVTTLENV--------S 1906
+ + TK EVS V K T T + + + NV S
Sbjct: 15440 EKPTDALQITKEEVSRSEAKTELSIPKAVREDKGTYTVTASNRLGSVFRNVHVEVYDRPS 15499
Query: 1907 PPRRARVTDATETTITISWRTKTET----ITGFQVDAVPANGQTPIQRTIKPDV--RSYT 1960
PPR VTD + ++W + IT + +D A+ + + + Y
Sbjct: 15500 PPRNLAVTDIKAESCYLTWDAPLDNGGSEITHYVIDKRDASRKKAEWEEVTNTAVEKRYG 15559
Query: 1961 ITGLQPGTDYKIYL-----YTLNDNARSSPVVI-DASTAIDAPSNLRFLATTPNSLLVSW 2014
I L P Y+ + Y ++D +S VVI D P + LA T S+LVSW
Sbjct: 15560 IWKLIPNGQYEFRVRAVNKYGISDECKSDKVVIQDPYRLPGPPGKPKVLARTKGSMLVSW 15619
Query: 2015 QPP----RARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLE 2055
PP + ITGY ++ + GSP V R +T+ + G+E
Sbjct: 15620 TPPLDNGGSPITGYWLEKREEGSPYWSRV--SRAPITKVGLKGVE 15662
Score = 78.2 bits (191), Expect = 9e-14
Identities = 286/1430 (20%), Positives = 494/1430 (34%), Gaps = 241/1430 (16%)
Query: 690 QEVTRFDFTTTSTST---------------PVTSNTVTGET-------------TPFSPL 721
++ R +F TT+TST P+T+ + GE P P+
Sbjct: 21107 KQTQRVNFETTATSTILNINECVRSDSGPYPLTARNIVGEVGDVITIQVHDIPGPPTGPI 21166
Query: 722 VATSESVTEITASSFVVSWVSASD----TVSGFRVEYELSEEGDEPQYLDLPSTA--TSV 775
E+++ SW + +S + VE + D +++L +T T+
Sbjct: 21167 -----KFDEVSSDFVTFSWDPPENDGGVPISNYVVE---MRQTDSTTWVELATTVIRTTY 21218
Query: 776 NIPDLLPGRKY-----IVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVR 830
L G +Y N Y + + I++ P P P V V S+ +
Sbjct: 21219 KATRLTTGLEYQFRVKAQNRYGVGPGITSACIVANYPFKVPGPPGTPQVTAVTKDSMTIS 21278
Query: 831 WSRP----QAPITGYRIVYSPSVEGSSTELNLPETANSVTL-------SDLQPGVQYNIT 879
W P +PI GY VE L +T + + S L G+ Y
Sbjct: 21279 WHEPLSDGGSPILGYH------VERKERNGILWQTVSKALVPGNIFKSSGLTDGIAYEFR 21332
Query: 880 IYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESA----VT 935
+ A +S P + D P L +T VT+ W PE +T
Sbjct: 21333 VIAENMAGKSKPSKPSEPMLALDPIDPPGKPVPL---NITRHTVTLKWAKPEYTGGFKIT 21389
Query: 936 GYRVDVIPVNLPGEHGQRLPIS---RNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQ 992
Y V+ +LP + S N F V+GL+ Y F+V A + P +
Sbjct: 21390 SYIVE--KRDLPNGRWLKANFSNILENEFT-VSGLTEDAAYEFRVIAKNAAGAISPPSEP 21446
Query: 993 QTT-----KLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQP-RQYNVGP 1046
++AP V D+ +L +RL ++ R P +++
Sbjct: 21447 SDAITCRDDVEAPKIKVDVKFKDTVILKAG-------EAFRLEADVSGRPPPTMEWSKDG 21499
Query: 1047 SVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSI-------------PP 1093
+ + ++++ +LV K + T PG PP
Sbjct: 21500 KELEGTAKLEIKIADFSTNLVN-KDSTRRDSGAYTLTATNPGGFAKHIFNVKVLDRPGPP 21558
Query: 1094 YN----TEVTETTIVITW-TPAPRIGFKLGVRPSQGGEAPREVTSDSGSIV------VSG 1142
TEVT V++W P G K+ Q E R ++ S V V+
Sbjct: 21559 EGPLAVTEVTSEKCVLSWFPPLDDGGAKIDHYIVQKRETSRLAWTNVASEVQVTKLKVTK 21618
Query: 1143 LTPGVEYVYTIQVLRD---GQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLT-----VS 1194
L G EY++ + + G+ ++ V V P PP NP+ +T V
Sbjct: 21619 LLKGNEYIFRVMAVNKYGVGEPLESEPV-LAVNPYGPPDP---PKNPEVTTITKDSMVVC 21674
Query: 1195 W---ERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVK 1251
W + +I Y + GQ+ + D L+ G EY +
Sbjct: 21675 WGHPDSDGGSEIINYIVERRDKAGQRWIKCNKKTLTD-LRYKVSGLTEGHEYEFRIMAEN 21733
Query: 1252 DDKESVP--------ISDTIIPEVPQLTDLSFVDITDSSIGLRWT-PL--NSSTIIGYRI 1300
S P DT+ P + +D + SSI + W P+ S I GY +
Sbjct: 21734 AAGISAPSPTSPFYKACDTVFKPGPP-GNPRVLDTSRSSISIAWNKPIYDGGSEITGYMV 21792
Query: 1301 TVVAAGEG-IPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAP-----TTLTQ 1354
+ E I YT+TGL +Y I + + + G P T +
Sbjct: 21793 EIALPEEDEWQIVTPPAGLKATSYTITGLTENQEYKIRIYAMNSEGLGEPALVPGTPKAE 21852
Query: 1355 QTAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNE------------EDV 1402
+PP +L D +V +I L + P+K E +
Sbjct: 21853 DRMLPPEIEL-----DADLRKVV-----TIRACCTLRLFVPIKGRPAPEVKWARDHGESL 21902
Query: 1403 AELSISPSDNAVVL----TNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFS 1458
+ SI + + +L N +Y+++V + +S + R P +
Sbjct: 21903 DKASIESTSSYTLLIVGNVNRFDSGKYILTVEN-SSGSKSAFVNVRVLDTPGPPQDLKVK 21961
Query: 1459 DITANSFTVHWIAPRATITGYRIRHH--PEHFSGRPREDRVPHS--RNSITLTNLTPGTE 1514
++T S T+ W P G +I+++ + S R V + + S + L G
Sbjct: 21962 EVTKTSVTLTWDPPLLD-GGSKIKNYIVEKRESTRKAYSTVATNCHKTSWKVDQLQEGCS 22020
Query: 1515 YVVSIVALN----GREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAP----AVTV 1566
Y ++A N G + S P + ++ T S+ +SW+ P +
Sbjct: 22021 YYFRVLAENEYGIGLPAETAESVKASERPLPPGKITLMDVTRNSVSLSWEKPEHDGGSRI 22080
Query: 1567 RYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPIS 1626
Y + G + TV + ATI+GL G +Y+ V A +G S +
Sbjct: 22081 LGYIVEMQTKGSDKWATCATV--KVTEATITGLIQGEEYSFRVSAQNEKGISDPRQLSVP 22138
Query: 1627 INYRTEIDKP------SQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKT 1680
+ + + P + V +D + V ++ +P + P +T
Sbjct: 22139 VIAKDLVIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLK-----QTTR 22193
Query: 1681 AGPDQTE----MTIEGL--QPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRP----KGLA 1730
+ TE +TI+ + YVV + N +GE+ + V +D+P +
Sbjct: 22194 VNAESTENNSLLTIKDACREDVGHYVVKL--TNSAGEAIETLNVIV--LDKPGPPTGPVK 22249
Query: 1731 FTDVDVDSIKIAWESPQ----GQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPG 1786
+V DSI ++W P+ ++ Y V ++ A T + L+ G
Sbjct: 22250 MDEVTADSITLSWGPPKYDGGSSINNYIVEKRDTSTTTWQIVSATVA-RTTIKACRLKTG 22308
Query: 1787 SEYTVSVVALH-----DDMESQPLIGTQSTAIPAPTDLK-FTQVTPTSLSAQWTPP---- 1836
EY + A + + S+P + +P P T + S+ QW P
Sbjct: 22309 CEYQFRIAAENRYGKSTYLNSEPTVAQYPFKVPGPPGTPVVTLSSRDSMEVQWNEPISDG 22368
Query: 1837 NVQLTGYRVRVTPKEKTGPM-KEINLAP-DSSSVVVSGLMVATKYEVSVYALKDTLTSRP 1894
++ GY + KE+ + ++N P + +GL +YE V A +P
Sbjct: 22369 GSRVIGYHLE--RKERNSILWVKLNKTPIPQTKFKTTGLEEGVEYEFRVSAENIVGIGKP 22426
Query: 1895 AQ--GVVTTLENVSPPRRARVTDATETTITISWRTKT----ETITGFQVD 1938
++ + PP R T ++T+ W+ T ITG+ V+
Sbjct: 22427 SKVSECYVARDPCDPPGRPEAIIVTRNSVTLQWKKPTYDGGSKITGYIVE 22476
Score = 75.1 bits (183), Expect = 8e-13
Identities = 286/1351 (21%), Positives = 472/1351 (34%), Gaps = 234/1351 (17%)
Query: 797 GEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ----APITGYRIVYSPSVEGS 852
G +++ + P P D V ++ S + W P + IT Y +
Sbjct: 17296 GSKTVSVKVLVLDKPGPPRDLEVSEIRKDSCYLTWKEPLDDGGSVITNYVVERRDVASAQ 17355
Query: 853 STELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRD 912
+ L+ S L G QY + A + V + P+D
Sbjct: 17356 WSPLSATSKKKSHFAKHLNEGNQYLFRVAAENQYGRGPFVETPKPIKALDPLHPPGPPKD 17415
Query: 913 LQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPVNLPGEHGQRLPISRNTFAE----V 964
L V+V +V+++W P+ S +TGY V+ E G + I T V
Sbjct: 17416 LHHVDVDKTEVSLVWNKPDRDGGSPITGYLVEY------QEEGTQDWIKFKTVTNLECVV 17469
Query: 965 TGLSPGVTYYFKVFA---VSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPR 1021
TGL G TY F+V A V G + + KL P+ V + V+ T R
Sbjct: 17470 TGLQQGKTYRFRVKAENIVGLGLPDTTIPIECQEKLVPPSVELDVKLIEGLVVKAGTTVR 17529
Query: 1022 --AQITGYRL-TVGLTRRGQPRQYNVGPSV------SKYPLRNL--QPASEYTVSLVAIK 1070
A I G + T T G + + +V S ++N + EY +++
Sbjct: 17530 FPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEYQITV---- 17585
Query: 1071 GNQESPKATGVFTTLQ--PGSSIPPYNT-EVTETTIVITWTPAPRIGFKLGVRPSQGGEA 1127
N K V T+ PG P N +VT + I+W P P G +
Sbjct: 17586 SNAAGSKTVAVHLTVLDVPGPPTGPINILDVTPEHMTISWQP-----------PKDDGGS 17634
Query: 1128 P--------REVTSDSGSIVVSG----------LTPGVEYVYTIQV---LRDGQERDA-P 1165
P ++ D+ +V SG L G EYV+ ++ + G D+ P
Sbjct: 17635 PVINYIVEKQDTRKDTWGVVSSGSSKTKLKIPHLQKGCEYVFRVRAENKIGVGPPLDSTP 17694
Query: 1166 IVNK-VVTPLSPPTNLHLEANPDTGVLTVSWERSTTPD---ITGY------------RIT 1209
V K +P SPP + + TVSW + ITGY R+
Sbjct: 17695 TVAKHKFSPPSPPGK-PVVTDITENAATVSWTLPKSDGGSPITGYYMERREVTGKWVRVN 17753
Query: 1210 TTP--------TNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISD 1261
TP T +GN+ E V A+ NL+ + + S +K + PI
Sbjct: 17754 KTPIADLKFRVTGLYEGNTYEFRVFAE-------NLAGLSKPSPSSDPIKACR---PIKP 17803
Query: 1262 TIIPEVPQLTDLSFVDITDSSIGLRWT-PLNS--STIIGYRITVVAAG--EGIPIFEDFV 1316
P P+L D S + L WT PL+ S I+GY + G + I +D +
Sbjct: 17804 PGPPINPKLKDKS-----RETADLVWTKPLSDGGSPILGYVVECQKPGTAQWNRINKDEL 17858
Query: 1317 DSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAV-----PPPTDLRFTNIGP 1371
+ V GL G +Y + GE P L + PP +L T
Sbjct: 17859 IRQCAF-RVPGLIEGNEYRFRIKAANIVGEGEPRELAESVIAKDILHPPEVELDVTCRDV 17917
Query: 1372 DTMRVTWA----------PPPSIDLTN---FLVRYSPVKNEEDV--AELSISPSDNAVVL 1416
T+RV P P I T LVR V +D+ EL I + A
Sbjct: 17918 ITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRA--- 17974
Query: 1417 TNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSP---TGIDFSDITANSFTVHWIAPR 1473
+Y++S + + + + LD P + +++T + T+ W P
Sbjct: 17975 ----DHGKYIISAKNSSGHAQGSAI----VNVLDRPGPCQNLKVTNVTKENCTISWENPL 18026
Query: 1474 ----ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNG----- 1524
+ IT + + + + G R + NL EY + A N
Sbjct: 18027 DNGGSEITNFIVEYRKPNQKGWSIVASDVTKR--LIKANLLANNEYYFRVCAENKVGVGP 18084
Query: 1525 --REESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYG---ETGGN 1579
++P+L P +L + T + + W P ++Y G+
Sbjct: 18085 TIETKTPILAINPIDRPGEPENLHIADKGKTFVYLKWRRPDYDGGSPNLSYHVERRLKGS 18144
Query: 1580 SPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASS--KPISINYRTEIDKPS 1637
+ K T + + V+ I + V + + S K + + ++ KP
Sbjct: 18145 DDWERVHKGSIKETHYM--VDRCVENQIYEFRVQTKNEGGESDWVKTEEVVVKEDLQKP- 18201
Query: 1638 QMQVTDVQDNSIS-VKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMT------I 1690
V D +S V + + + R+ + P P T D T++T I
Sbjct: 18202 ------VLDLKLSGVLTVKAGDTI---RLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKI 18252
Query: 1691 EGLQPTVEYVVSVYAQNPSGE--------SQPLVQTAVTNI-DRP---KGLAFTDVDVDS 1738
+ + ++ ++ ++ G+ + V A N+ D+P + L DV D
Sbjct: 18253 DTRADSSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATVNVLDKPGPVRNLKIVDVSSDR 18312
Query: 1739 IKIAWESPQG----QVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSV- 1793
+ W+ P+ ++ Y + + + + A T + L G+EY V
Sbjct: 18313 CTVCWDPPEDDGGCEIQNYILEKCETKRMVWSTYSATVLTPGTTVTR-LIEGNEYIFRVR 18371
Query: 1794 ----VALHDDMESQPLIGTQSTAIPA-PTDLKFTQVTPTSLSAQWTPPNVQ----LTGYR 1844
+ ES+P+I P P + T+V+ ++ W PP +TGY
Sbjct: 18372 AENKIGTGPPTESKPVIAKTKYDKPGRPDPPEVTKVSKEEMTVVWNPPEYDGGKSITGYF 18431
Query: 1845 VRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKD------TLTSRPAQGV 1898
+ K T + A + V L+ +Y+ V A + +L SRP
Sbjct: 18432 LEKKEKHSTRWVPVNKSAIPERRMKVQNLLPDHEYQFRVKAENEIGIGEPSLPSRPVVAK 18491
Query: 1899 VTTLENVSPPRRARVTDATETTITISWRTKT----ETITGFQV-------DAVPANGQTP 1947
+E PP RV D T+ +IT+ W I G+ V DA P G
Sbjct: 18492 -DPIEPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAPIIGYVVEMRPKIADASPDEGWKR 18550
Query: 1948 IQRTIKPDVRSYTITGLQPGTDYKIYLYTLN 1978
+ + +T+T L +Y+ + N
Sbjct: 18551 CNAAAQLVRKEFTVTSLDENQEYEFRVCAQN 18581
Score = 71.2 bits (173), Expect = 1e-11
Identities = 350/1644 (21%), Positives = 556/1644 (33%), Gaps = 296/1644 (18%)
Query: 628 IQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISI 684
+ W +P+ S I+ Y++ R + W T + T++GL G Y ++ +
Sbjct: 16635 LTWFSPEDDGGSPITNYVIEKRESDRRA-WTPVTYTVTRQNATVQGLIQGKAYFFRIAAE 16693
Query: 685 QQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSAS 744
G F TS + + T P P V E+T ++ ++W
Sbjct: 16694 NSIGMGP-----FVETSEALVIREPI----TVPERP---EDLEVKEVTKNTVTLTWNPPK 16741
Query: 745 DTVSGFRVEYELSEE--GDEPQYLDLPSTATS--VNIPDLLPGRKYIVNVYQISEDGEQS 800
+ Y L G E + S + L G Y V ++ G+
Sbjct: 16742 YDGGSEIINYVLESRLIGTEKFHKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGK 16801
Query: 801 LILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPE 860
T T D PT+ + +R A Y P V E ++ E
Sbjct: 16802 PSFCTKPITCKDELAPPTLHLDFRDKLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLE 16861
Query: 861 TANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQET---TGTPRSDTVPSPRD----L 913
+ T P I A + VV++ T G + + V P +
Sbjct: 16862 --DDRTHIKTTPATLALEKIKAKRSDSGKYCVVVENSTGSRKGFCQVNVVDRPGPPVGPV 16919
Query: 914 QFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPGEHGQRLPI---SRNTFAEVTG 966
F EVT + I W PP S +T Y ++ V +P+ S T +V+
Sbjct: 16920 SFDEVTKDYMVISWKPPLDDGGSKITNYIIEKKEVG----KDVWMPVTSASAKTTCKVSK 16975
Query: 967 LSPGVTYYFKVFAVSHGRESKPLTAQQTTKLD------APTNLQFVNETDSTVLVRWTPP 1020
L G Y F++ A + S PL + D AP T + LV W P
Sbjct: 16976 LLEGKDYIFRIHAENLYGISDPLVSDSMKAKDRFRVPDAPDQPIVTEVTKDSALVTWNKP 17035
Query: 1021 R---AQITGYRLTVGLTRRGQPRQYNVGP--SVSKYPLRNLQPASEYTVSLVA---IKGN 1072
IT Y L T + + P +K+ + +L +Y + A I
Sbjct: 17036 HDGGKPITNYILEKRETMSKRWARVTKDPIHPYTKFRVPDLLEGCQYEFRVSAENEIGIG 17095
Query: 1073 QESPKATGVFTTLQPGSSIPPYNTEVTETT---IVITWTPAPRIGFKLGVRPSQGGEAPR 1129
SP + VF PP N E +TT + +TW P PR
Sbjct: 17096 DPSPPSKPVFAKDPIAKPSPPVNPEAIDTTCNSVDLTWQP------------------PR 17137
Query: 1130 EVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTG 1189
D GS ++ Y+ Q + D + R A N E+ P+T
Sbjct: 17138 H---DGGSKILG-------YIVEYQKVGDEEWRRA--------------NHTPESCPETK 17173
Query: 1190 VLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPG---LEYNVS 1246
T +R+ G+ + H + D L P L+ N++
Sbjct: 17174 YKVTGLRDGQTYK---FRVLAVNAAGES-----DPAHVPEPVLVKDRLEPPELILDANMA 17225
Query: 1247 VYTVKDDKESVPISDT-----IIPEVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGYRIT 1301
++ + + DT II VP F +T W + RI
Sbjct: 17226 ------REQHIKVGDTLRLSAIIKGVP------FPKVT-------WKKEDRDAPTKARID 17266
Query: 1302 VVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAVPPP 1361
V G + I + G Y++T P +SV L+ PP
Sbjct: 17267 VTPVGSKLEI-RNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDKPG------------PP 17313
Query: 1362 TDLRFTNIGPDTMRVTWAPPPSID---LTNFLVRYSPVKNEEDVAELSISPSDNAVVLTN 1418
DL + I D+ +TW P +TN++V V + + + LS + + +
Sbjct: 17314 RDLEVSEIRKDSCYLTWKEPLDDGGSVITNYVVERRDVASAQ-WSPLSATSKKKSHFAKH 17372
Query: 1419 LLPGTEYVVSVSSVYEQHESTPLRGRQKT--GLDS------PTGIDFSDITANSFTVHWI 1470
L G +Y+ V++ Q+ P K LD P + D+ ++ W
Sbjct: 17373 LNEGNQYLFRVAAE-NQYGRGPFVETPKPIKALDPLHPPGPPKDLHHVDVDKTEVSLVWN 17431
Query: 1471 APR----ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN--- 1523
P + ITGY + + E + V + +T L G Y + A N
Sbjct: 17432 KPDRDGGSPITGYLVEYQEEGTQDWIKFKTVTNLE--CVVTGLQQGKTYRFRVKAENIVG 17489
Query: 1524 -GREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPV 1582
G ++ + I Q + VP +E+ L++ TVR+ I G P
Sbjct: 17490 LGLPDTTIPIECQEKL--VPPSVELDVKLIEGLVVK---AGTTVRFPAIIRGVP---VPT 17541
Query: 1583 QEFTVPGSK---------------STATISGL--KPGVDYTITVYAVTGRGDSPASSKPI 1625
++T GS+ S TI + +Y ITV + A SK +
Sbjct: 17542 AKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEYQITV-------SNAAGSKTV 17594
Query: 1626 SINYRTEIDKPSQ----MQVTDVQDNSISVKWLP----SSSPVTGYRVTT--TPKNGPGP 1675
+++ T +D P + + DV +++ W P SPV Y V T K+ G
Sbjct: 17595 AVHL-TVLDVPGPPTGPINILDVTPEHMTISWQPPKDDGGSPVINYIVEKQDTRKDTWGV 17653
Query: 1676 TKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDR------PKGL 1729
++G +T++ I LQ EYV V A+N G PL T + P
Sbjct: 17654 V---SSGSSKTKLKIPHLQKGCEYVFRVRAENKIGVGPPLDSTPTVAKHKFSPPSPPGKP 17710
Query: 1730 AFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQ----GLRP 1785
TD+ ++ ++W P+ Y + + + + A+L+ GL
Sbjct: 17711 VVTDITENAATVSWTLPKSDGGSPITGYYMERREVTGKWVRVN-KTPIADLKFRVTGLYE 17769
Query: 1786 GSEYTVSVVALH------DDMESQPLIGTQSTAIPA-PTDLKFTQVTPTSLSAQWTPP-- 1836
G+ Y V A + S P+ + P P + K + + WT P
Sbjct: 17770 GNTYEFRVFAENLAGLSKPSPSSDPIKACRPIKPPGPPINPKLKDKSRETADLVWTKPLS 17829
Query: 1837 --NVQLTGYRVRVTPKEKTGPMKEINLAP--DSSSVVVSGLMVATKYEVSVYALKDTLTS 1892
+ GY V K T IN + V GL+ +Y + A
Sbjct: 17830 DGGSPILGYVVE-CQKPGTAQWNRINKDELIRQCAFRVPGLIEGNEYRFRIKAANIVGEG 17888
Query: 1893 RP---AQGVVTTLENVSPPR-------RARVTDATETTITISWRTK-------TETITG- 1934
P A+ V+ + + PP R +T TI I R K T T G
Sbjct: 17889 EPRELAESVIAK-DILHPPEVELDVTCRDVITVRVGQTIRILARVKGRPEPDITWTKEGK 17947
Query: 1935 -----FQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVID 1989
+VD + + +Q IK VR+ Y I + +A+ S +V
Sbjct: 17948 VLVREKRVDLIQDLPRVELQ--IKEAVRA-------DHGKYIISAKNSSGHAQGSAIV-- 17996
Query: 1990 ASTAIDAP---SNLRFLATTPNSLLVSWQPP----RARITGYIIKYEKPGSPPREVVPRP 2042
+D P NL+ T + +SW+ P + IT +I++Y KP +V
Sbjct: 17997 --NVLDRPGPCQNLKVTNVTKENCTISWENPLDNGGSEITNFIVEYRKPNQKGWSIV--- 18051
Query: 2043 RPGVTEATI-TGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELPQLVTLPHPNLHGPEI 2101
VT+ I L EY V A +N P I K P L P PE
Sbjct: 18052 ASDVTKRLIKANLLANNEYYFRVCA-ENKVGVGPTIETK----TPILAINPIDRPGEPEN 18106
Query: 2102 LDVPSTVQKTPFV--THPGYDTGN 2123
L + + ++ P YD G+
Sbjct: 18107 LHIADKGKTFVYLKWRRPDYDGGS 18130
Score = 67.8 bits (164), Expect = 1e-10
Identities = 172/864 (19%), Positives = 306/864 (35%), Gaps = 155/864 (17%)
Query: 1325 VTGLEPGIDYDISVITLINGGESAPT------TLTQQTAVPPPTDLRFTNIGPDTMRVTW 1378
VT L G +Y V + G P L T PPT L T++ ++M + W
Sbjct: 25944 VTKLLKGNEYIFRVTGVNKYGVGEPLESVAIKALDPFTVPSPPTSLEITSVTKESMTLCW 26003
Query: 1379 APPPS---IDLTNFLVRYSPVKNEEDVAELSISP-SDNAVVLTNLLPGTEYVVSV----- 1429
+ P S +++ +++ KN ++ P D V T L G EY V
Sbjct: 26004 SRPESDGGSEISGYIIERRE-KNSLRWVRVNKKPVYDLRVKSTGLREGCEYEYRVYAENA 26062
Query: 1430 SSVYEQHESTPL-RGRQKTGLDS-PTGIDFSDITANSFTVHWIAP----RATITGYRIRH 1483
+ + E++PL R L S P+ D + T+ W+ P A ITGY + +
Sbjct: 26063 AGLSLPSETSPLIRAEDPVFLPSPPSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEY 26122
Query: 1484 HPEHFSGRPREDRVPHSRNS-ITLTNLTPGTEYVVSIVALN-----------------GR 1525
+ + + R + T++ LT G EYV + ++N R
Sbjct: 26123 --KKSDDTDWKTSIQSLRGTEYTISGLTTGAEYVFRVKSVNKVGASDPSDSSDPQIAKER 26180
Query: 1526 EESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEF 1585
EE PL S++ + L V A ++ + + V + + + + + +
Sbjct: 26181 EEEPLF----DIDSEMRKTLIVKAGASFTMTVPFRGRPVP----NVLWSKPDTDLRTRAY 26232
Query: 1586 T-VPGSKSTATI--SGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVT 1642
S+++ TI + YT+T+ V A+S + + P+ + V
Sbjct: 26233 VDTTDSRTSLTIENANRNDSGKYTLTIQNVLS-----AASLTLVVKVLDTPGPPTNITVQ 26287
Query: 1643 DVQDNSISVKW-LPSS---SPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVE 1698
DV S + W +P + +PV Y + + T ++ + LQ
Sbjct: 26288 DVTKESAVLSWDVPENDGGAPVKNYHIEKREASKKAWVSV-TNNCNRLSYKVTNLQEGAI 26346
Query: 1699 YVVSVYAQNPSGESQPLVQTAVTNIDR----PKGLAFTDVDVDSIKIAWESPQGQVSRYR 1754
Y V +N G P I P+ L T + DS+ + W P+
Sbjct: 26347 YYFRVSGENEFGVGIPAETKEGVKITEKPSPPEKLGVTSISKDSVSLTWLKPEHDGGSRI 26406
Query: 1755 VTY--SSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTA 1812
V Y + E G + + GLR SEY V A E+Q
Sbjct: 26407 VHYVVEALEKGQKNWVKCAVAKSTHHVVSGLRENSEYFFRVFA-----ENQ-------AG 26454
Query: 1813 IPAPTDLKFTQVTPTSLSAQWTPPNVQL-----------TGYRVRVTPKEKTGPMKEINL 1861
+ P +L + P + Q PP + + G ++V P+ ++ L
Sbjct: 26455 LSDPREL----LLPVLIKEQLEPPEIDMKNFPSHTVYVRAGSNLKVDIPISGKPLPKVTL 26510
Query: 1862 APD----------SSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGV------VTTLENV 1905
+ D ++ + L + K V+ A + +T+ + G + L+
Sbjct: 26511 SRDGVPLKATMRFNTEITAENLTINLKESVTADAGRYEITAANSSGTTKAFINIVVLDRP 26570
Query: 1906 SPPR-RARVTDATETTITISWR---------------TKTETITGFQVDAVPANGQTPIQ 1949
PP ++D TE ++T+ W K ET T AV +
Sbjct: 26571 GPPTGPVVISDITEESVTLKWEPPKYDGGSQVTNYILLKRETST-----AVWTEVSATVA 26625
Query: 1950 RTIKPDVRSYTITGLQPGTDYKIYL-----YTLNDNARSSPVVIDASTAIDAPSNLRFLA 2004
RT+ + L G +Y+ + + ++D+ S+ V + P + ++
Sbjct: 26626 RTM------MKVMKLTTGEEYQFRIKAENRFGISDHIDSACVTVKLPYTTPGPPSTPWVT 26679
Query: 2005 -TTPNSLLVSWQPP----RARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTE 2059
T S+ V W P + + GY ++ + S + + T +T + G
Sbjct: 26680 NVTRESITVGWHEPVSNGGSAVVGYHLEMKDRNSILWQKANKLVIRTTHFKVTTISAGLI 26739
Query: 2060 YTIYVIAL------KNNQKSEPLI 2077
Y V A K + SEP++
Sbjct: 26740 YEFRVYAENAAGVGKPSHPSEPVL 26763
Score = 65.1 bits (157), Expect = 8e-10
Identities = 102/477 (21%), Positives = 189/477 (39%), Gaps = 56/477 (11%)
Query: 628 IQWNAPQP---SHISKYILRWRPKNSVGRWKEAT-IPGHLNSYTIKGLKPGVVYEGQLIS 683
+ W P+ S ++ YI+ R + RW +P + Y GL G+ YE ++ +
Sbjct: 29950 LTWYPPEDDGGSQVTGYIVE-RKEVRADRWVRVNKVPVTMTRYRSTGLTEGLEYEHRVTA 30008
Query: 684 IQQYGHQEVTRFDFTTTSTSTPVTS-NTVTGETTPFSPLVATSESVTEITASSFVVSWVS 742
I G + +R S P+ + + + P +P VT+ T +S ++W
Sbjct: 30009 INARGSGKPSR-------PSKPIVAMDPIAPPGKPQNP------RVTDTTRTSVSLAWSV 30055
Query: 743 ASDT----VSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDG- 797
D V+G+ +E + ++ + + P+ + L G +Y V + G
Sbjct: 30056 PEDEGGSKVTGYLIEMQKVDQHEWTKCNTTPTKIREYTLTHLPQGAEYRFRVLACNAGGP 30115
Query: 798 -EQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWS---RPQAPITGYRI-VYSPSVEGS 852
E + + T + T PD +D+ I VR R PI G + + EG
Sbjct: 30116 GEPAEVPGTVKVTEMLEYPDYELDERYQEGIFVRQGGVIRLTIPIKGKPFPICKWTKEGQ 30175
Query: 853 STE----LNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVP 908
+ ET + + + G + +E V I+ G+P S P
Sbjct: 30176 DISKRAMIATSETHTELVIKEADRGDSGTYDL-VLENKCGKKAVYIKVRVIGSPNSPEGP 30234
Query: 909 SPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEV 964
L++ ++ V + W PP + + GY ++ V + + R T V
Sbjct: 30235 ----LEYDDIQVRSVRVSWRPPADDGGADILGYILERREVPKAAWYTIDSRV-RGTSLVV 30289
Query: 965 TGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTN--------LQFVNETDSTVLVR 1016
GL V Y+F+V A + SKPL +++ P N + ++ T S+V +
Sbjct: 30290 KGLKENVEYHFRVSAENQFGISKPLKSEEPVTPKTPLNPPEPPSNPPEVLDVTKSSVSLS 30349
Query: 1017 WTPPR----AQITGYRLTVGLTRRGQPRQYN-VGPSVSKYPLRNLQPASEYTVSLVA 1068
W+ P+ +++TGY + T + ++N + + Y + L P +EY ++A
Sbjct: 30350 WSRPKDDGGSRVTGYYIERKETSTDKWVRHNKTQITTTMYTVTGLVPDAEYQFRIIA 30406
Score = 60.1 bits (144), Expect = 3e-08
Identities = 177/822 (21%), Positives = 289/822 (35%), Gaps = 149/822 (18%)
Query: 1360 PPTDLRFTNIGPDTMRVTWAPPPS---IDLTNFLVRYSPVKNEEDVAELSISPSDNAVVL 1416
P +L T + + W P + + ++V +K + V + S V
Sbjct: 13092 PVRNLEVTETFDGEVSLAWEEPLTDGGSKIIGYVVERRDIKRKTWVLATDRAESCEFTVT 13151
Query: 1417 TNLLPGTEYVVSVSS-----VYEQHES-TPLRGRQKTGLDSPT-GIDFSDITANSFTVHW 1469
G EY+ VS+ E E+ P+ R K + P + +D+ ++ W
Sbjct: 13152 GLQKGGVEYLFRVSARNRVGTGEPVETDNPVEARSKYDVPGPPLNVTITDVNRFGVSLTW 13211
Query: 1470 IAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGR 1525
P A IT Y I + V S T+T++ G EY + R
Sbjct: 13212 EPPEYDGGAEITNYVIELRDKTSIRWDTAMTVRAEDLSATVTDVVEGQEYSFRV-----R 13266
Query: 1526 EESPLLIGQQSTVSDV------------PRDLEVVAATPTSLLISWDAP----AVTVRYY 1569
++ + +G+ S + P +L T +S+ + W+ P + Y
Sbjct: 13267 AQNRIGVGKPSAATPFVKVADPIERPSPPVNLTSSDQTQSSVQLKWEPPLKDGGSPILGY 13326
Query: 1570 RITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINY 1629
I E G ++ ++ + T ++GL+ G Y V A G S S +
Sbjct: 13327 IIERCEEGKDNWIRCNMKLVPELTYKVTGLEKGNKYLYRVSAENKAGVSDPSEILGPLTA 13386
Query: 1630 RTEIDKPSQMQVTDVQDNSISVKWLPSSS--PVTGYRVTTTPKNGPGPTKTKTAGPDQTE 1687
+P+ M ++ +D + P + P TGY P PT T G E
Sbjct: 13387 DDAFVEPT-MDLSAFKDGLEVIVPNPITILVPSTGY---------PRPTATWCFGDKVLE 13436
Query: 1688 ----MTIEGLQPTVEYVVSVYAQNPSG----ESQPLVQTAVTNID--------RPKGLAF 1731
+ ++ L E V+S ++ G + + V+T ID PK L F
Sbjct: 13437 TGDRVKMKTLSAYAELVISPSERSDKGIYTLKLENRVKTISGEIDVNVIARPSAPKELKF 13496
Query: 1732 TDVDVDSIKIAWESPQ----GQVSRY--------RVTYSSPEDGIHEL-FPAPDGEEDTA 1778
D+ DS+ + WE P ++ Y R T++ D + +L F PD
Sbjct: 13497 GDITKDSVHLTWEPPDDDGGSPLTGYVVEKREVSRKTWTKVMDFVTDLEFTVPD------ 13550
Query: 1779 ELQGLRPGSEYTVSVVALHDDMESQPL-------IGTQSTAIPAPTDLKFTQVTPTSLSA 1831
L G EY V A + +P + T +T P ++K+ T S+
Sbjct: 13551 ----LVQGKEYLFKVCARNKCGPGEPAYVDEPVNMSTPATVPDPPENVKWRDRTANSIFL 13606
Query: 1832 QWTPP----NVQLTGYRVRVTPKEKTGPMKEINLAPD--SSSVVVSGLMVATKYEVSVYA 1885
W PP ++ GY V P+ G K + + + V+GL Y V A
Sbjct: 13607 TWDPPKNDGGSRIKGYIVERCPR---GSDKWVACGEPVAETKMEVTGLEEGKWYAYRVKA 13663
Query: 1886 LKDTLTSRPAQGVVTTLENVSPPRRARVTDATETT-----------ITISWRTKTE---T 1931
L S+P++ P + D E +T+ TK E T
Sbjct: 13664 LNRQGASKPSR----------PTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPAT 13713
Query: 1932 ITGFQVDAVPANGQTPIQRTIKPDVR----------SYTITGLQPGTDYKIYLYTLNDNA 1981
+TG P T +K D R + TI + + +N
Sbjct: 13714 VTG---KPEPKITWTKADMILKQDKRITIENVPKKSTVTIVDSKRSDTGTYIIEAVNVCG 13770
Query: 1982 RSSPVV-IDASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPR 2036
R++ VV ++ P+ T S L++W PPR ++IT Y+++ S
Sbjct: 13771 RATAVVEVNVLDKPGPPAAFDITDVTNESCLLTWNPPRDDGGSKITNYVVERRATDS--- 13827
Query: 2037 EVVPRPRPGV--TEATITGLEPGTEYTIYVIALKNNQKSEPL 2076
EV + V T T L P EY V A EP+
Sbjct: 13828 EVWHKLSSTVKDTNFKATKLIPNKEYIFRVAAENMYGVGEPV 13869
Score = 58.9 bits (141), Expect = 6e-08
Identities = 325/1703 (19%), Positives = 588/1703 (34%), Gaps = 267/1703 (15%)
Query: 611 PVEVFITETPSQP-----------NSHPIQWNAPQPS---HISKYILRWRPKNSVGRWKE 656
P+ V PS+P +S + W+ P+ + I+ Y + R + S WK
Sbjct: 27648 PITVITLGPPSKPKGPIRFDEIKADSVILSWDVPEDNGGGEITCYSIEKR-ETSQTNWKM 27706
Query: 657 ATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETT 716
++ + L Y+ ++ + +YG S P+ S+ + +
Sbjct: 27707 VCSSVARTTFKVPNLVKDAEYQFRVRAENRYG-------------VSQPLVSSIIVAKHQ 27753
Query: 717 PFSPLVATSESVTEITASSFVVSW----VSASDTVSGFRVEYELSEEGDEPQYLDLPSTA 772
P + +T+ ++W V+GF VE + + P +
Sbjct: 27754 FRIPGPPGKPVIYNVTSDGMSLTWDAPVYDGGSEVTGFHVEKKERNSILWQKVNTSPISG 27813
Query: 773 TSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDP--TVDQVDDT--SIV 828
L+ G Y VY + G S S+ T +P DP T D +D T +I
Sbjct: 27814 REYRATGLVEGLDYQFRVYAENSAGLSSPS-DPSKFTLAVSPVDPPGTPDYIDVTRETIT 27872
Query: 829 VRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETAN-SVTLSDLQPGVQYNITIYA- 882
++W+ P + I GY I E N + + T++ L PG +Y I A
Sbjct: 27873 LKWNPPLRDGGSKIVGYSIEKRQGNE-RWVRCNFTDVSECQYTVTGLSPGDRYEFRIIAR 27931
Query: 883 -----VEENQESTPVVIQQETTGTPRSDTVPSPRD---LQFVEVTDVKVTIMWTPPESAV 934
+ +S+ +++ ++ P + P D ++ E +K + P V
Sbjct: 27932 NAVGTISPPSQSSGIIMTRDENVPPIVEFGPEYFDGLIIKSGESLRIKALVQGRPVPR-V 27990
Query: 935 TGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFK--------VFAVSHGRES 986
T ++ V I + E+T + + + + V+ V S
Sbjct: 27991 TWFKDGV-------------EIEKRMNMEITDVLGSTSLFVRDATRDHRGVYTVEAKNAS 28037
Query: 987 KPLTAQQTTKL-DAPTN----LQFVNETDSTVLVRWTPPR----AQITGYRLTVGLTRRG 1037
A+ K+ D P ++F N T + + W P A IT Y + T R
Sbjct: 28038 GSAKAEIKVKVQDTPGKVVGPIRFTNITGEKMTLWWDAPLNDGCAPITHYIIEKRETSRL 28097
Query: 1038 QPRQYNVGPSVSKYPLRNLQPASEYTVSLVAI------KGNQESPKATGVFTTLQPGSSI 1091
Y L +EY + A+ + P + T+ I
Sbjct: 28098 AWALIEDKCEAQSYTAIKLINGNEYQFRVSAVNKFGVGRPLDSDPVVAQIQYTVPDAPGI 28157
Query: 1092 PPYNTEVTETTIVITWTPAPRIG------FKLGVRPSQGGEAPREVTSDSGS---IVVSG 1142
P + +T +I +TW G + L R + + ++ S V+G
Sbjct: 28158 PE-PSNITGNSITLTWARPESDGGSEIQQYILERREKKSTRWVKVISKRPISETRFKVTG 28216
Query: 1143 LTPGVEYVYTIQVLRDGQERDAPIVNKVVT---PLSPPTNLHLEANPDTGVLTVSWERST 1199
LT G EY + + A +++++ P++PP + DT TVS E S
Sbjct: 28217 LTEGNEYEFHVMAENAAGVGPASGISRLIKCREPVNPPGPPTVVKVTDTSKTTVSLEWSK 28276
Query: 1200 TP-----DITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKD-- 1252
+I GY I + + + ++ T +L G EY V +
Sbjct: 28277 PVFDGGMEIIGYIIEMCKADLGDWHKVNAEACV-KTRYTVTDLQAGEEYKFRVSAINGAG 28335
Query: 1253 DKESVPISDTI-------IPEVPQLTDLSFVDITDSSIGLR--------------WTPLN 1291
+S ++ TI PE+ + + + +R W+ +
Sbjct: 28336 KGDSCEVTGTIKAVDRLTAPELDIDANFKQTHVVRAGASIRLFIAYQGRPTPTAVWSKPD 28395
Query: 1292 SSTIIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTT 1351
S+ + I + + + E+ + G YT+T + +G +S T
Sbjct: 28396 SNLSLRADIHTTDSFSTLTV-ENCNRNDAGKYTLT------------VENNSGSKSITFT 28442
Query: 1352 LTQQTAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAE---LSIS 1408
+ PP + F ++ + + W P +D + Y K E +S
Sbjct: 28443 VKVLDTPGPPGPITFKDVTRGSATLMW-DAPLLDGGARIHHYVVEKREASRRSWQVISEK 28501
Query: 1409 PSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDS----PTGIDFSDITANS 1464
+ + +L G Y VS+V E P + P +D D + +S
Sbjct: 28502 CTRQIFKVNDLAEGVPYYFRVSAVNEYGVGEPYEMPEPIVATEQPAPPRRLDVVDTSKSS 28561
Query: 1465 FTVHWIAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRN-SITLTNLTPGTEYVVSI 1519
+ W+ P + ITGY + + G H++ + T+ L TEY +
Sbjct: 28562 AVLAWLKPDHDGGSRITGYLLEMRQK---GSDFWVEAGHTKQLTFTVERLVEKTEYEFRV 28618
Query: 1520 VALNGREESPLLIGQQSTVSDVPR-----DLEVV--------AATPTSL---LISWDAPA 1563
A N S S + P+ DL + A +P ++ + AP
Sbjct: 28619 KAKNDAGYSEPREAFSSVIIKEPQIEPTADLTGITNQLITCKAGSPFTIDVPISGRPAPK 28678
Query: 1564 VTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVD--YTITVYAVTGRGDSPAS 1621
VT + + ET S T ++T T+ G Y +T+ ++ A
Sbjct: 28679 VTWKLEEMRLKETDRVS----ITTTKDRTTLTVKDSMRGDSGRYFLTL-------ENTAG 28727
Query: 1622 SKPISINYRTEIDKPSQM----QVTDVQDNSISVKWLP----SSSPVTGYRVTTTPKNGP 1673
K S+ I +P + +V+ V S + W + +T Y + ++G
Sbjct: 28728 VKTFSVTV-VVIGRPGPVTGPIEVSSVSAESCVLSWGEPKDGGGTEITNY-IVEKRESGT 28785
Query: 1674 GPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAV------TNIDRPK 1727
+ + +T++ + L +EY V ++N G S+PL + P
Sbjct: 28786 TAWQLVNSSVKRTQIKVTHLTKYMEYSFRVSSENRFGVSKPLESAPIIAEHPFVPPSAPT 28845
Query: 1728 GLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGE----EDTAELQGL 1783
V +++ I WE P + Y + + + + + E ++ GL
Sbjct: 28846 RPEVYHVSANAMSIRWEEPYHDGGSKIIGYWVEKKERNTILWVKENKVPCLECNYKVTGL 28905
Query: 1784 RPGSEYTVSVVALH------DDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPP- 1836
G EY AL+ S+P++ + AP + T VT +++S W+ P
Sbjct: 28906 VEGLEYQFRTYALNAAGVSKASEASRPIMA--QNPVDAPGRPEVTDVTRSTVSLIWSAPA 28963
Query: 1837 ---NVQLTGYRVRVTPKEKTGP---MKEINLAPDSSSVVVSGLMVATKYEVSVYALKDT- 1889
++ GY + P + G +K + V+ L YE V A
Sbjct: 28964 YDGGSKVVGYIIERKPVSEVGDGRWLKCNYTIVSDNFFTVTALSEGDTYEFRVLAKNAAG 29023
Query: 1890 LTSRPAQ--GVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVP------ 1941
+ S+ ++ G VT + +PP+ DA ++ R ++ + V P
Sbjct: 29024 VISKGSESTGPVTCRDEYAPPKAE--LDARLHGDLVTIRAGSDLVLDAAVGGKPEPKIIW 29081
Query: 1942 ANGQTPIQRTIKPDV-----RSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDA 1996
G + K + R+ + +D Y T+ NA + V +D+
Sbjct: 29082 TKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSGKYTLTVK-NASGTKAVSVMVKVLDS 29140
Query: 1997 P---SNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREVVPRPRPGVTEA 2049
P L T ++W P+ A IT YI++ + +V P ++
Sbjct: 29141 PGPCGKLTVSRVTQEKCTLAWSLPQEDGGAEITHYIVERRETSRLNWVIVEGECPTLS-Y 29199
Query: 2050 TITGLEPGTEYTIYVIALKN-----NQKSEPLIGRKKTDELPQLVTLPHPNLHGPEILDV 2104
+T L EY V A+ +SEP++ R T+P P P I +
Sbjct: 29200 VVTRLIKNNEYIFRVRAVNKYGPGVPVESEPIVARNS-------FTIPSP----PGIPEE 29248
Query: 2105 PSTVQKTPFV--THPGYDTGNGI 2125
T ++ + T P D GN I
Sbjct: 29249 VGTGKEHIIIQWTKPESDGGNEI 29271
Score = 55.5 bits (132), Expect = 7e-07
Identities = 128/535 (23%), Positives = 202/535 (37%), Gaps = 90/535 (16%)
Query: 593 GIGEWHCQPLQTYPSSSGPVEVFITETPSQP-------NSHPIQWNAPQ---PSHISKYI 642
GIGE PL + P ++ + + P +P NS + W P+ S ++ Y
Sbjct: 16298 GIGE----PLDSEPETARNL-FSVPGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPVTGYW 16352
Query: 643 LRWRPKNSVGRWK-------EATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRF 695
L + S RWK +A G SY + GL G Y+ ++ +I G +
Sbjct: 16353 LEMKDTTSK-RWKRVNRDPIKAMTLGV--SYKVTGLIEGSDYQFRVYAINAAGVGPASL- 16408
Query: 696 DFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWV----SASDTVSGFR 751
S P T+ P +P VT+ T SS + W V+G+
Sbjct: 16409 ------PSDPATARD------PIAPPGPPFPKVTDWTKSSADLEWSPPLKDGGSKVTGYI 16456
Query: 752 VEYELSEEGDEP--QYLDLPSTATSVNIPDLLPGRKY-----IVNVYQISEDGEQSLILS 804
VEY+ EEG E + D T + + L G Y VN+ I E GE + ++
Sbjct: 16457 VEYK--EEGKEEWEKGKDKEVRGTKLVVTGLKEGAFYKFRVRAVNIAGIGEPGEVTDVIE 16514
Query: 805 TSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETA-- 862
PD +D IVV I P+V + E LP+ A
Sbjct: 16515 MKDRLVS---PDLQLDASVRDRIVVHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEATI 16571
Query: 863 ------NSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFV 916
+S+ + + Q Q ++ A E E +I VP P F+
Sbjct: 16572 ETTAISSSMVIKNCQRSHQGVYSLLAKNEAGERKKTIIVDVLD-------VPGPVGTPFL 16624
Query: 917 --EVTDVKVTIMWTPPE----SAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPG 970
+T+ + W PE S +T Y ++ + ++R A V GL G
Sbjct: 16625 AHNLTNESCKLTWFSPEDDGGSPITNYVIEKRESDRRAWTPVTYTVTRQN-ATVQGLIQG 16683
Query: 971 VTYYFKVFA---VSHG---RESKPLTAQQT-TKLDAPTNLQFVNETDSTVLVRWTPPR-- 1021
Y+F++ A + G S+ L ++ T + P +L+ T +TV + W PP+
Sbjct: 16684 KAYFFRIAAENSIGMGPFVETSEALVIREPITVPERPEDLEVKEVTKNTVTLTWNPPKYD 16743
Query: 1022 --AQITGYRLTVGLTRRGQPRQYNVGPSVS-KYPLRNLQPAS--EYTVSLVAIKG 1071
++I Y L L + + +S KY ++ L+ EY VS V I G
Sbjct: 16744 GGSEIINYVLESRLIGTEKFHKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVG 16798
Score = 52.8 bits (125), Expect = 4e-06
Identities = 80/336 (23%), Positives = 120/336 (35%), Gaps = 46/336 (13%)
Query: 602 LQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQP---SHISKYILRWRPKN-SVGRWKEA 657
++ Y S P + +T+ ++ S + W+AP S I+ Y++ R + W+E
Sbjct: 15492 VEVYDRPSPPRNLAVTDIKAE--SCYLTWDAPLDNGGSEITHYVIDKRDASRKKAEWEEV 15549
Query: 658 TIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTP 717
T Y I L P YE ++ ++ +YG + + D V + P
Sbjct: 15550 TNTAVEKRYGIWKLIPNGQYEFRVRAVNKYGISDECKSD-------KVVIQDPYRLPGPP 15602
Query: 718 FSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTA----- 772
P V T S +VSW D Y L + + Y S A
Sbjct: 15603 GKPKVLAR------TKGSMLVSWTPPLDNGGSPITGYWLEKREEGSPYWSRVSRAPITKV 15656
Query: 773 ----TSVNIPDLLPGRKY-----IVNVYQISEDGEQSLILSTSQTTAPDAPPD-PTVDQV 822
N+P LL G KY +N I E S P PP P V
Sbjct: 15657 GLKGVEFNVPRLLEGVKYQFRAMAINAAGIGPPSEPSDPEVAGDPIFPPGPPSCPEVKDK 15716
Query: 823 DDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPE---TANSVTLSDLQPGVQ 875
+SI + W P +PI GY + +N P+ T + +L+ +
Sbjct: 15717 TKSSISLGWKPPAKDGGSPIKGYIVEMQEEGTTDWKRVNEPDKLITTCECVVPNLKELRK 15776
Query: 876 YNITIYAVEENQESTPVVIQQETTG-TPRSDTVPSP 910
Y + AV E ES P +TTG P +D P
Sbjct: 15777 YRFRVKAVNEAGESEP----SDTTGEIPATDIQEEP 15808
Score = 50.4 bits (119), Expect = 2e-05
Identities = 182/937 (19%), Positives = 327/937 (34%), Gaps = 131/937 (13%)
Query: 1277 DITDSSIGLRWTPLNS---STIIGYRITV-VAAGEGIPIFEDFVDSSVGYYTVTGLEPGI 1332
DIT+++ + WT S S I GY + G+ + + + + + VTGL G
Sbjct: 17714 DITENAATVSWTLPKSDGGSPITGYYMERREVTGKWVRVNKTPIADLK--FRVTGLYEGN 17771
Query: 1333 DYDISVITLINGGESAPTTLTQQTAV-------PPPTDLRFTNIGPDTMRVTWAPPPSID 1385
Y+ V G S P+ + PP + + + +T + W P S D
Sbjct: 17772 TYEFRVFAENLAGLSKPSPSSDPIKACRPIKPPGPPINPKLKDKSRETADLVWTKPLS-D 17830
Query: 1386 LTNFLVRYSPVKNEEDVAELSISPSDN-----AVVLTNLLPGTEYVVSVSSVYEQHESTP 1440
+ ++ Y + A+ + D A + L+ G EY + + E P
Sbjct: 17831 GGSPILGYVVECQKPGTAQWNRINKDELIRQCAFRVPGLIEGNEYRFRIKAANIVGEGEP 17890
Query: 1441 LRGRQKT---GLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRV 1497
+ + P ++ D+T + I R++ PE +E +V
Sbjct: 17891 RELAESVIAKDILHPPEVEL-DVTCRDVITVRVGQTIRILA-RVKGRPEPDITWTKEGKV 17948
Query: 1498 PHSRNSITLTNLTPGTE-------------YVVSIVALNGREESPLLIGQQSTVSDVP-- 1542
+ L P E Y++S +G + ++ V D P
Sbjct: 17949 LVREKRVDLIQDLPRVELQIKEAVRADHGKYIISAKNSSGHAQGSAIVN----VLDRPGP 18004
Query: 1543 -RDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISG--- 1598
++L+V T + ISW+ P + G + + + E+ P K + ++
Sbjct: 18005 CQNLKVTNVTKENCTISWENP--------LDNGGSEITNFIVEYRKPNQKGWSIVASDVT 18056
Query: 1599 -------LKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQ---MQVTDVQDNS 1648
L +Y V A G P I ID+P + + + D
Sbjct: 18057 KRLIKANLLANNEYYFRVCAENKVGVGPTIETKTPILAINPIDRPGEPENLHIADKGKTF 18116
Query: 1649 ISVKW----LPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVY 1704
+ +KW SP Y V K + +T ++ Y V
Sbjct: 18117 VYLKWRRPDYDGGSPNLSYHVERRLKGSDDWERVHKGSIKETHYMVDRCVENQIYEFRVQ 18176
Query: 1705 AQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSI-------KIAWESPQGQVSRYRVTY 1757
+N GES V+T + D+ + + I E+ V +
Sbjct: 18177 TKNEGGESD-WVKTEEVVVKEDLQKPVLDLKLSGVLTVKAGDTIRLEAGVRGKPFPEVAW 18235
Query: 1758 SSPEDGIHELFPAP----DGEEDTAELQGLRP----GSEYTVSVVALHDDMESQPLIGTQ 1809
+ +D +L +P D D+++ + G +Y V+ + +
Sbjct: 18236 TKDKDAT-DLTRSPRVKIDTRADSSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATVNVL 18294
Query: 1810 STAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVV 1869
P +LK V+ + W PP G ++ EK K + + S++V+
Sbjct: 18295 DKPGPV-RNLKIVDVSSDRCTVCWDPPEDD-GGCEIQNYILEKC-ETKRMVWSTYSATVL 18351
Query: 1870 VSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENV---------SPPRRARVTDATETT 1920
G V E + Y + ++ G T + V P VT ++
Sbjct: 18352 TPGTTVTRLIEGNEYIFRVRAENKIGTGPPTESKPVIAKTKYDKPGRPDPPEVTKVSKEE 18411
Query: 1921 ITISWRTKT----ETITGFQVDAVPANGQ--TPIQRTIKPDVRSYTITGLQPGTDYKIYL 1974
+T+ W ++ITG+ ++ + P+ ++ P+ R + L P +Y+ +
Sbjct: 18412 MTVVWNPPEYDGGKSITGYFLEKKEKHSTRWVPVNKSAIPE-RRMKVQNLLPDHEYQFRV 18470
Query: 1975 YTLND------NARSSPVVI-DASTAIDAPSNLRFLATTPNSLLVSWQPP----RARITG 2023
N+ + S PVV D P+N R + TT +S+ + W P A I G
Sbjct: 18471 KAENEIGIGEPSLPSRPVVAKDPIEPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAPIIG 18530
Query: 2024 YIIKYEK--PGSPPREVVPRPRPGV----TEATITGLEPGTEYTIYVIALKNNQKSEPLI 2077
Y+++ + P E R E T+T L+ EY V A NQ +
Sbjct: 18531 YVVEMRPKIADASPDEGWKRCNAAAQLVRKEFTVTSLDENQEYEFRVCA--QNQ-----V 18583
Query: 2078 GRKKTDELPQLVTLPHPNLHGPEILDVPSTVQKTPFV 2114
G + EL + + P L PEI D+ ++++K V
Sbjct: 18584 GIGRPAELKEAIK-PKEILEPPEI-DLDASMRKLVIV 18618
Score = 48.5 bits (114), Expect = 8e-05
Identities = 107/537 (19%), Positives = 187/537 (34%), Gaps = 65/537 (12%)
Query: 610 GPVEVFITETPSQPNSHPIQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSY 666
GPV ++ + H + W P+ S ++ YI+ R + W T S+
Sbjct: 18700 GPVSDLKVSDVTKTSCH-VSWAPPENDGGSQVTHYIVEKREADRK-TWSTVTPEVKKTSF 18757
Query: 667 TIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSE 726
+ L PG Y ++ ++ +YG T PV ++ E P L
Sbjct: 18758 HVTNLVPGNEYYFRVTAVNEYG-------PGVPTDVPKPVLASDPLSEPDPPRKL----- 18805
Query: 727 SVTEITASSFVVSWV----SASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLP 782
VTE+T +S ++W+ + G+ Y E+ + S+ + L
Sbjct: 18806 EVTEMTKNSATLAWLPPLRDGGAKIDGYITSYREEEQPADRWTEYSVVKDLSLVVTGLKE 18865
Query: 783 GRKY-----IVNVYQISEDGEQSLILSTSQTTAPD---APPDPTVDQVDDTSIVVRWSRP 834
G+KY N +S E + + P P T+ I
Sbjct: 18866 GKKYKFRVAARNAVGVSLPREAEGVYEAKEQLLPPKILMPEQITIKAGKKLRIEAHVYGK 18925
Query: 835 QAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDL--QPGVQYNITIYAVEENQESTPV 892
P ++ V S ++ ++++ + + D+ + Y++T
Sbjct: 18926 PHPTCKWKKGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIK 18985
Query: 893 VIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPG 948
V+ + G P+ P D+ ++ ++ W P S +T Y V+ V+ G
Sbjct: 18986 VVVMDAPGPPQ-----PPFDISDIDAD--ACSLSWHIPLEDGGSNITNYIVEKCDVS-RG 19037
Query: 949 EHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKL------DAPTN 1002
+ L T V L PG Y F+V A + S+PLT+ + P N
Sbjct: 19038 DWVTALASVTKTSCRVGKLIPGQEYIFRVRAENRFGISEPLTSPKMVAQFPFGVPSEPKN 19097
Query: 1003 LQFVNETDSTVLVRWTPPRAQ----ITGYRLTVGLTRRGQPRQYNVGPSV---SKYPLRN 1055
+ + V W P + I GY + R ++ ++YP
Sbjct: 19098 ARVTKVNKDCIFVAWDRPDSDGGSPIIGY--LIERKERNSLLWVKANDTLVRSTEYPCAG 19155
Query: 1056 LQPASEYTVSLVAIKGNQESP--KATGVFTTLQPGSSIPPYNTE---VTETTIVITW 1107
L EY+ + A+ SP K T T P PP E VT++T+ + W
Sbjct: 19156 LVEGLEYSFRIYALNKAGSSPPSKPTEYVTARMPVD--PPGKPEVIDVTKSTVSLIW 19210
Score = 47.4 bits (111), Expect = 2e-04
Identities = 68/293 (23%), Positives = 108/293 (36%), Gaps = 33/293 (11%)
Query: 730 EITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQY----LDLPSTATSVNIPDLLPGRK 785
+I S VSW +D + Y L E + P+ +D TS+ + L +
Sbjct: 30239 DIQVRSVRVSWRPPADDGGADILGYIL-ERREVPKAAWYTIDSRVRGTSLVVKGLKENVE 30297
Query: 786 YIVNVYQISEDGEQSLILSTSQTTA-----PDAPPD--PTVDQVDDTSIVVRWSRPQ--- 835
Y V ++ G + S T P PP P V V +S+ + WSRP+
Sbjct: 30298 YHFRVSAENQFGISKPLKSEEPVTPKTPLNPPEPPSNPPEVLDVTKSSVSLSWSRPKDDG 30357
Query: 836 -APITGYRIVYSPSVEGSSTELNLPE-TANSVTLSDLQPGVQYNITIYAV------EENQ 887
+ +TGY I + N + T T++ L P +Y I A E +
Sbjct: 30358 GSRVTGYYIERKETSTDKWVRHNKTQITTTMYTVTGLVPDAEYQFRIIAQNDVGLSETSP 30417
Query: 888 ESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIP 943
S PVV + D P +L+ + ++ VT+ W PE + GY V+
Sbjct: 30418 ASEPVVCKDPF------DKPSQPGELEILSISKDSVTLQWEKPECDGGKEILGYWVEYRQ 30471
Query: 944 VNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTK 996
++ + GL Y F+VFA + S+P + K
Sbjct: 30472 SGDSAWKKSNKERIKDKQFTIGGLLEATEYEFRVFAENETGLSRPRRTAMSIK 30524
Score = 43.9 bits (102), Expect = 0.002
Identities = 50/204 (24%), Positives = 83/204 (40%), Gaps = 22/204 (10%)
Query: 717 PFSPLVATSESVTEITASSFVVSWVSASDT----VSGFRVEYELSEEGDEPQYLDLPSTA 772
P P+V + + +S V+SW +D ++ + VE ++EG E Q + +
Sbjct: 30726 PTGPIV-----IEALLKNSAVISWKPPADDGGSWITNYVVEKCEAKEGAEWQLVSSAISV 30780
Query: 773 TSVNIPDLLPGRKYIV-----NVYQISEDGE-QSLILSTSQTTAPDAPPDPTVDQVDDTS 826
T+ I +L Y N + IS+ E S+++ S P AP PT+ V S
Sbjct: 30781 TTCRIVNLTENAGYYFRVSAQNTFGISDPLEVSSVVIIKSPFEKPGAPGKPTITAVTKDS 30840
Query: 827 IVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSV-TLSDLQPGVQYNITIY 881
VV W P A I Y + + + E +V ++ +L G++Y +
Sbjct: 30841 CVVAWKPPASDGGAKIRNYYLEKREKKQNKWISVTTEEIRETVFSVKNLIEGLEYEFRVK 30900
Query: 882 AVEENQESTPVVIQQETTGTPRSD 905
ES I + TP+SD
Sbjct: 30901 CENLGGESEWSEISEPI--TPKSD 30922
Score = 41.2 bits (95), Expect = 0.013
Identities = 92/413 (22%), Positives = 157/413 (38%), Gaps = 51/413 (12%)
Query: 1376 VTWAPPPSID---LTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSV 1432
++W PP +TN++V K + +S + S + NL Y VS+
Sbjct: 30742 ISWKPPADDGGSWITNYVVEKCEAKEGAEWQLVSSAISVTTCRIVNLTENAGYYFRVSAQ 30801
Query: 1433 YEQHESTPLRGRQKTGLDSPTGID-------FSDITANSFTVHWIAPRATITGYRIRHHP 1485
S PL + SP + +T +S V W P A+ G +IR++
Sbjct: 30802 NTFGISDPLEVSSVVIIKSPFEKPGAPGKPTITAVTKDSCVVAW-KPPASDGGAKIRNYY 30860
Query: 1486 EHFSGRPREDRVPHSRNSITLT-----NLTPGTEYVVSIVA--LNGREESPLLIGQQSTV 1538
+ + + + I T NL G EY + L G E + +
Sbjct: 30861 LEKREKKQNKWISVTTEEIRETVFSVKNLIEGLEYEFRVKCENLGGESEWSEISEPITPK 30920
Query: 1539 SDVP----------RDLEVVAATPTSLLISWDA-PAVTVRYYRITYGET----GGNSPVQ 1583
SDVP R+L V + +L+ P V++YR G+ G +Q
Sbjct: 30921 SDVPIQAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYR--QGKEIIADGLKYRIQ 30978
Query: 1584 EFTVPGSKSTATISGLKPGVDYTITVYAV--TGRGDSPASSKPISINYRTEIDKPSQMQ- 1640
EF G I+ + D TVY V T +G S + + + + +I P ++
Sbjct: 30979 EFK--GGYHQLIIASV---TDDDATVYQVRATNQGGSVSGTASLEVEVPAKIHLPKTLEG 31033
Query: 1641 ---VTDVQDNSISVKWLPSSS---PVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQ 1694
V ++ +S+K +P S PV ++ + G + + + G++
Sbjct: 31034 MGAVHALRGEVVSIK-IPFSGKPDPVITWQKGQDLIDNNGHYQVIVTRSFTSLVFPNGVE 31092
Query: 1695 PTVEYVVSVYAQNPSGESQPLVQTAVTNI-DRPKGLAFTDVDVDSIKIAWESP 1746
V A+N G Q V+ V ++ D P+G+ +DV DS+ + W P
Sbjct: 31093 RKDAGFYVVCAKNRFGIDQKTVELDVADVPDPPRGVKVSDVSRDSVNLTWTEP 31145
Score = 37.7 bits (86), Expect = 0.14
Identities = 36/131 (27%), Positives = 53/131 (40%), Gaps = 8/131 (6%)
Query: 894 IQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPVNLPGE 949
I Q+T +D PR ++ +V+ V + WT P S +T Y V+ E
Sbjct: 31109 IDQKTVELDVADVPDPPRGVKVSDVSRDSVNLTWTEPASDGGSKITNYIVEKCATT--AE 31166
Query: 950 HGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQ--TTKLDAPTNLQFVN 1007
R+ +R T V L +Y F+V A + SKP + TK D + +
Sbjct: 31167 RWLRVGQARETRYTVINLFGKTSYQFRVIAENKFGLSKPSEPSEPTITKEDKTRAMNYDE 31226
Query: 1008 ETDSTVLVRWT 1018
E D T V T
Sbjct: 31227 EVDETREVSMT 31237
Score = 35.0 bits (79), Expect = 0.92
Identities = 38/169 (22%), Positives = 71/169 (42%), Gaps = 17/169 (10%)
Query: 1610 YAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWL-PSS---SPVTGYRV 1665
Y V + K + ++ D P ++V+DV +S+++ W P+S S +T Y V
Sbjct: 31099 YVVCAKNRFGIDQKTVELDVADVPDPPRGVKVSDVSRDSVNLTWTEPASDGGSKITNYIV 31158
Query: 1666 TTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPL--VQTAVTNI 1723
+ A +T T+ L Y V A+N G S+P + +T
Sbjct: 31159 EKCATTAERWLRVGQA--RETRYTVINLFGKTSYQFRVIAENKFGLSKPSEPSEPTITKE 31216
Query: 1724 DRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPD 1772
D+ + + + D +VD + +VS + ++SS ++ + A D
Sbjct: 31217 DKTRAMNY-DEEVDETR--------EVSMTKASHSSTKELYEKYMIAED 31256
>gi|110349717 titin isoform novex-2 [Homo sapiens]
Length = 27118
Score = 175 bits (443), Expect = 6e-43
Identities = 375/1615 (23%), Positives = 611/1615 (37%), Gaps = 226/1615 (13%)
Query: 630 WNAPQPSHISK---YILRWRPKNSVG--RWKEA--TIPGHLNSYTIKGLKPGVVYEGQLI 682
W+AP SK YI+ +P + VG RW + TI N +T+ L G YE +++
Sbjct: 22654 WSAPAYDGGSKVVGYIIERKPVSEVGDGRWLKCNYTIVSD-NFFTVTALSEGDTYEFRVL 22712
Query: 683 SIQQYGHQEVTRFDFTTTSTST-PVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWV 741
+ G + S ST PVT + VT S V+
Sbjct: 22713 AKNAAGV-------ISKGSESTGPVTCRDEYAPPKAELDARLHGDLVTIRAGSDLVL--- 22762
Query: 742 SASDTVSGFRVEYELS-EEGDEP---------QYLDLPSTATSVNIPDLLPGRKYIVNVY 791
D G + E ++ +GD+ QY +TA + D KY + V
Sbjct: 22763 ---DAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAV-IKFCDRSDSGKYTLTVK 22818
Query: 792 QISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ----APITGYRIVYSP 847
S G +++ + +P TV +V + WS PQ A IT Y +
Sbjct: 22819 NAS--GTKAVSVMVKVLDSPGPCGKLTVSRVTQEKCTLAWSLPQEDGGAEITHYIVERRE 22876
Query: 848 S-------VEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG 900
+ VEG L S ++ L +Y + AV + PV + E
Sbjct: 22877 TSRLNWVIVEGECPTL-------SYVVTRLIKNNEYIFRVRAVNKYGPGVPV--ESEPIV 22927
Query: 901 TPRSDTVPSPRDL-QFVEVTDVKVTIMWTPPES----AVTGYRVDVIPV-NLPGEHGQRL 954
S T+PSP + + V + I WT PES ++ Y VD +L +
Sbjct: 22928 ARNSFTIPSPPGIPEEVGTGKEHIIIQWTKPESDGGNEISNYLVDKREKKSLRWTRVNKD 22987
Query: 955 PISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNL-------QFVN 1007
+ +T +VT L G Y F+V AV+ S+P A P+ + V+
Sbjct: 22988 YVVYDTRLKVTSLMEGCDYQFRVTAVNAAGNSEPSEASNFISCREPSYTPGPPSAPRVVD 23047
Query: 1008 ETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSV--SKYPLRNLQPASE 1061
T ++ + WT P I GY L + Q + + ++ +++ + +L+ +
Sbjct: 23048 TTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDTDQWYRVHTNATIRNTEFTVPDLKMGQK 23107
Query: 1062 YT--VSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGV 1119
Y+ V+ V +KG E ++ ++P I + E+ + + T R G L +
Sbjct: 23108 YSFRVAAVNVKGMSEYSES---IAEIEPVERIEIPDLELADD---LKKTVTIRAGASLRL 23161
Query: 1120 RPSQGGEAPREVT-----SDSGSIVVSGLTPGVEYV------------YTIQVLRDGQER 1162
S G P +T D S + T + YTI+ ++
Sbjct: 23162 MVSVSGRPPPVITWSKQGIDLASRAIIDTTESYSLLIVDKVNRYDAGKYTIEAENQSGKK 23221
Query: 1163 DAPIVNKVV-TPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSL 1221
A ++ KV TP P+ E + D+ +T++WE P I G P N
Sbjct: 23222 SATVLVKVYDTPGPCPSVKVKEVSRDS--VTITWE---IPTIDG----GAPVNNYIVEKR 23272
Query: 1222 EEVVHA-----DQSSCTFDNLSPGLEYNVSVYTVKDDK-----ESVPISDTI-IPEVPQL 1270
E + A + S T +S +E + + V + E SD + + EVP +
Sbjct: 23273 EAAMRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYGIGEPCETSDAVLVSEVPLV 23332
Query: 1271 -TDLSFVDITDSSIGLRW-TPL--NSSTIIGYRITVVAAGEGIPIFEDFVDSSVGYYTVT 1326
L VD+T S++ L W PL S + GY + AG + + +V +TVT
Sbjct: 23333 PAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGTERWMKVVTLKPTVLEHTVT 23392
Query: 1327 GLEPGIDYDISVITLINGGESAP----TTLT-QQTAVPPPTDLRFTNIGPDTMRV----- 1376
L G Y + G S P T +T Q V P DL + + T+ V
Sbjct: 23393 SLNEGEQYLFRIRAQNEKGVSEPRETVTAVTVQDLRVLPTIDL--STMPQKTIHVPAGRP 23450
Query: 1377 -------TWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSV 1429
PPP+ F ++E E + + T + EY + +
Sbjct: 23451 VELVIPIAGRPPPAASW--FFAGSKLRESERVTVETHTKVAKLTIRETTIRDTGEYTLEL 23508
Query: 1430 SSVY-EQHESTPLRGRQKTGLDSPTG-IDFSDITANSFTVHWIAPR----ATITGYRIRH 1483
+V E+ + K G PTG I +I A S T+ W P A ++GY +
Sbjct: 23509 KNVTGTTSETIKVIILDKPG--PPTGPIKIDEIDATSITISWEPPELDGGAPLSGYVVEQ 23566
Query: 1484 HPEHFSG-RPREDRVPHSRNSITLTNLTPGTEYVVSIVALN----GREESPLLIGQQST- 1537
H G P + V +R++ T LT G EYV + A N G +I +S+
Sbjct: 23567 RDAHRPGWLPVSESV--TRSTFKFTRLTEGNEYVFRVAATNRFGIGSYLQSEVIECRSSI 23624
Query: 1538 -VSDVPRDLEVVAATPTSLLISWDAP----AVTVRYYRITYGETGGNSPVQEFTVPGSKS 1592
+ P L++ + + ++W P V Y + E + V+ VP + +
Sbjct: 23625 RIPGPPETLQIFDVSRDGMTLTWYPPEDDGGSQVTGYIVERKEVRADRWVRVNKVPVTMT 23684
Query: 1593 TATISGLKPGVDYTITVYAVTGRGDSPAS--SKPI-SINYRTEIDKPSQMQVTDVQDNSI 1649
+GL G++Y V A+ RG S SKPI +++ KP +VTD S+
Sbjct: 23685 RYRSTGLTEGLEYEHRVTAINARGSGKPSRPSKPIVAMDPIAPPGKPQNPRVTDTTRTSV 23744
Query: 1650 SVKWL----PSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYA 1705
S+ W S VTGY + + TK T E T+ L EY V A
Sbjct: 23745 SLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTKCNTTPTKIREYTLTHLPQGAEYRFRVLA 23804
Query: 1706 QNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDS-IKIAWESPQGQVSRYRVTYSSPEDGI 1764
N G +P + + L + D ++D + QG V R + I
Sbjct: 23805 CNAGGPGEPAEVPGTVKV--TEMLEYPDYELDERYQEGIFVRQGGVIRLTIPIKGKPFPI 23862
Query: 1765 HELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMES------------QPLIGTQSTA 1812
+ +G +D ++ + +T V+ D +S + + +
Sbjct: 23863 CKW--TKEG-QDISKRAMIATSETHTELVIKEADRGDSGTYDLVLENKCGKKAVYIKVRV 23919
Query: 1813 IPAPTD----LKFTQVTPTSLSAQWTPP----NVQLTGYRV--RVTPKEKTGPMKEINLA 1862
I +P L++ + S+ W PP + GY + R PK I+
Sbjct: 23920 IGSPNSPEGPLEYDDIQVRSVRVSWRPPADDGGADILGYILERREVPK---AAWYTIDSR 23976
Query: 1863 PDSSSVVVSGLMVATKYEVSVYALKDTLTSRP--AQGVVTTLENVSPP----RRARVTDA 1916
+S+VV GL +Y V A S+P ++ VT ++PP V D
Sbjct: 23977 VRGTSLVVKGLKENVEYHFRVSAENQFGISKPLKSEEPVTPKTPLNPPEPPSNPPEVLDV 24036
Query: 1917 TETTITISW-RTKTE---TITGFQVDAVPANGQTPIQRT-IKPDVRSYTITGLQPGTDYK 1971
T++++++SW R K + +TG+ ++ + ++ + YT+TGL P +Y+
Sbjct: 24037 TKSSVSLSWSRPKDDGGSRVTGYYIERKETSTDKWVRHNKTQITTTMYTVTGLVPDAEYQ 24096
Query: 1972 IYLYTLND------NARSSPVVI-DASTAIDAPSNLRFLATTPNSLLVSWQPPRA----R 2020
+ ND + S PVV D P L L+ + +S+ + W+ P
Sbjct: 24097 FRIIAQNDVGLSETSPASEPVVCKDPFDKPSQPGELEILSISKDSVTLQWEKPECDGGKE 24156
Query: 2021 ITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEP 2075
I GY ++Y + G + + R + TI GL TEY V A S P
Sbjct: 24157 ILGYWVEYRQSGDSAWKKSNKERIKDKQFTIGGLLEATEYEFRVFAENETGLSRP 24211
Score = 147 bits (371), Expect = 1e-34
Identities = 366/1672 (21%), Positives = 605/1672 (36%), Gaps = 240/1672 (14%)
Query: 612 VEVFITETPSQPNSHPIQ----------WNAPQP---SHISKYILRWRPKNSVGRWKEAT 658
VEV + + P P + I WN P+ S I+ Y++ R +S W + +
Sbjct: 7471 VEVNVLDKPGPPAAFDITDVTNESCLLTWNPPRDDGGSKITNYVVERRATDSEV-WHKLS 7529
Query: 659 IPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPF 718
++ L P Y ++ + YG E PV ++ +T +
Sbjct: 7530 STVKDTNFKATKLIPNKEYIFRVAAENMYGVGE-------------PVQASPITAKYQFD 7576
Query: 719 SPLVATSESVTEITASSFVVSWVSASDT----VSGFRVEYELSEEGDEPQYLDLPSTATS 774
P T ++IT + ++W D ++G+ VE + + +P T+
Sbjct: 7577 PPGPPTRLEPSDITKDAVTLTWCEPDDDGGSPITGYWVERLDPDTDKWVRCNKMPVKDTT 7636
Query: 775 VNIPDLLPGRKYIVNVY--QISEDGEQSL----ILSTSQTTAPDAPPDPTVDQVDDTSIV 828
+ L +KY V ++ G+ S IL P P PTV V TS+
Sbjct: 7637 YRVKGLTNKKKYRFRVLAENLAGPGKPSKSTEPILIKDPIDPPWPPGKPTVKDVGKTSVR 7696
Query: 829 VRWSRPQ----APITGY--RIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYA 882
+ W++P+ A I Y ++ + + E +P T + L L G +Y+ + A
Sbjct: 7697 LNWTKPEHDGGAKIESYVIEMLKTGTDEWVRVAEGVPTTQH--LLPGLMEGQEYSFRVRA 7754
Query: 883 VEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYR 938
V + ES P + PR L+ + +T + WT PE S +T Y
Sbjct: 7755 VNKAGESEPSEPSDPVLCREKLYPPSPPRWLEVINITKNTADLKWTVPEKDGGSPITNYI 7814
Query: 939 VDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSH-GR------ESKPLTA 991
V+ V G + ++T VT L+ G Y F+V A + G+ E L
Sbjct: 7815 VEKRDVRRKGWQTVDTTV-KDTKCTVTPLTEGSLYVFRVAAENAIGQSDYTEIEDSVLAK 7873
Query: 992 QQTTKLDAPTNLQFVNETDSTVLVRWTPPR--AQITGYRLTVGLTRRGQPRQYNVGPSVS 1049
T P L V+ T V ++W PP+ R + R R G +
Sbjct: 7874 DTFTTPGPPYALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKERLGTRWVKAGKTAG 7933
Query: 1050 KYPLRNLQPASEYTVSLVAIKGNQES-----PKATGVFTTLQPGS-SIPPYNTEVTET-- 1101
+ E T ++ E+ + T + + P S PP + VT+
Sbjct: 7934 PDCNFRVTDVIEGTEVQFQVRAENEAGVGHPSEPTEILSIEDPTSPPSPPLDLHVTDAGR 7993
Query: 1102 -TIVITWTP------APRIGFKLGVRPSQGGEAPREVTS----DSGSIVVSGLTPGVEYV 1150
I I W P +P IG+ + + P G E V S D V G+ P EYV
Sbjct: 7994 KHIAIAWKPPEKNGGSPIIGYHVEMCP-VGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYV 8052
Query: 1151 YTIQVLRD-GQERDAPIVNKVVT--PLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYR 1207
++ + G + I VV P PT + LE + ++ + E+ + P +R
Sbjct: 8053 LRVRAVNAIGVSEPSEISENVVAKDPDCKPT-IDLETH---DIIVIEGEKLSIP--VPFR 8106
Query: 1208 ITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEY------NVSVYTV----KDDKESV 1257
PT + +EV +D+ + D++S LE + +YT+ K +
Sbjct: 8107 AVPVPTVSWHKDG-KEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATA 8165
Query: 1258 PISDTIIPEVPQLTDLSFVDITDSSIGLRWTPL---NSSTIIGYRITVVAAGEG--IPIF 1312
I+ +I D+ DIT SS L W P + I+ Y + AG IP+
Sbjct: 8166 SINVKVIGLPGPCKDIKASDITKSSCKLTWEPPEFDGGTPILHYVLERREAGRRTYIPVM 8225
Query: 1313 EDFVDSSVGYYTVTGLEPGIDY--DISVITLINGGESAP---TTLTQQTAVP--PPTDLR 1365
S +TV L P +Y + + + GGE + Q P PP D+
Sbjct: 8226 SGENKLS---WTVKDLIPNGEYFFRVKAVNKVGGGEYIELKNPVIAQDPKQPPDPPVDVE 8282
Query: 1366 FTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLT----NLLP 1421
N + M +TW PP D + ++ Y K + +LT L
Sbjct: 8283 VHNPTAEAMTITW-KPPLYDGGSKIMGYIIEKIAKGEERWKRCNEHLVPILTYTAKGLEE 8341
Query: 1422 GTEYVVSVSSVYEQHESTPLRGRQKT----GLDSP---------------TGIDFSDITA 1462
G EY V + S P R T +D+P +D S +
Sbjct: 8342 GKEYQFRVRAENAAGISEPSRATPPTKAVDPIDAPKVILRTSLEVKRGDEIALDASISGS 8401
Query: 1463 NSFTVHWIAPRATITGYRIRHHPEHFSGRPR------EDRVPHSRNSITLTNLTPGTE-- 1514
T+ WI I I+ R + E V +++ N G
Sbjct: 8402 PYPTITWIKDENVIVPEEIKKRAAPLVRRRKGEVQEEEPFVLPLTQRLSIDNSKKGESQL 8461
Query: 1515 ------------YVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAP 1562
Y++ + +G ++P + T P + TS+L W+ P
Sbjct: 8462 RVRDSLRPDHGLYMIKVENDHGIAKAPCTVSVLDTPGP-PINFVFEDIRKTSVLCKWEPP 8520
Query: 1563 -----AVTVRYYRITYGETGGNSPVQEFTVPGS---KSTATISGLKPGVDYTITVYAVTG 1614
+ + Y T + P E+ V S +++ L G +Y V A
Sbjct: 8521 LDDGGSEIINY---TLEKKDKTKPDSEWIVVTSTLRHCKYSVTKLIEGKEYLFRVRAENR 8577
Query: 1615 RGDS-PASSKP-ISINYRTEIDKPSQMQVTDVQDNSISVKW---LPSSSPVTGYRVTTTP 1669
G P SKP ++ + D P + V DV NS+ VKW + SP+ GY +
Sbjct: 8578 FGPGPPCVSKPLVAKDPFGPPDAPDKPIVEDVTSNSMLVKWNEPKDNGSPILGYWLEKRE 8637
Query: 1670 KNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSG------ESQPLVQTAVTNI 1723
N ++ + + + ++GL + YV V A+N +G S P +
Sbjct: 8638 VNSTHWSRVNKSLLNALKANVDGLLEGLTYVFRVCAENAAGPGKFSPPSDPKTAHDPISP 8697
Query: 1724 DRPKGLAFTDVDVDSIKIAWESPQ----GQVSRYRVTYSSPEDGIHELFPAPDGEEDTAE 1779
P TD +I++ WE P G++ Y V G +E + +
Sbjct: 8698 PGPPIPRVTDTSSTTIELEWEPPAFNGGGEIVGYFV--DKQLVGTNEWSRCTEKMIKVRQ 8755
Query: 1780 --LQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPN 1837
++ +R G++Y + V A++ E P TQ + P + ++ +
Sbjct: 8756 YTVKEIREGADYKLRVSAVNAAGEGPP-GETQPVTVAEPQEPPAVELDVS------VKGG 8808
Query: 1838 VQLTGYRVRVTPKEKTG---PMKEINLAP---DSSSVVVSGLMVATKYEVSVYALKDTLT 1891
+Q+ + P TG P K D VV+ V TK E+ +KD L
Sbjct: 8809 IQIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKDRVVIDN--VGTKSEL---IIKDALR 8863
Query: 1892 SRPAQGVVTTLENVS---PPRRARVTDATETTI------------TISWRTKTE----TI 1932
+ V+T + R V D + ++W + I
Sbjct: 8864 KDHGRYVITATNSCGSKFAAARVEVFDVPGPVLDLKPVVTNRKMCLLNWSDPEDDGGSEI 8923
Query: 1933 TGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDAST 1992
TGF ++ A T ++ I+ + ITGL G +YK + N PV I
Sbjct: 8924 TGFIIERKDAKMHT-WRQPIETERSKCDITGLLEGQEYKFRVIAKNKFGCGPPVEIGPIL 8982
Query: 1993 AID------APSNLRFLATTPNSLLVSWQPPRAR----ITGYIIKYEKPGSPPREVVPRP 2042
A+D +P L + T +++ + W+ PR+ I GYII+ + P E V +
Sbjct: 8983 AVDPLGPPTSPERLTYTERTKSTITLDWKEPRSNGGSPIQGYIIEKRRHDKPDFERVNKR 9042
Query: 2043 RPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRK---KTDELPQLVTL 2091
T + L+ Y V A+ +SEP + + DE+P + L
Sbjct: 9043 LCPTTSFLVENLDEHQMYEFRVKAVNEIGESEPSLPLNVVIQDDEVPPTIKL 9094
Score = 144 bits (362), Expect = 1e-33
Identities = 288/1427 (20%), Positives = 522/1427 (36%), Gaps = 163/1427 (11%)
Query: 696 DFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYE 755
D+T T+ ++ + + P S + ++ + ++SW + Y
Sbjct: 13060 DYTITAENSSGSKSATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYI 13119
Query: 756 LSE-EGDEPQYLDLPSTA--TSVNIPDLLPGRKY-----IVNVYQISEDGEQSLILSTSQ 807
+ + E P + + +T TS ++ L+ G +Y N Y + + ++ +
Sbjct: 13120 VDKRETSRPNWAQVSATVPITSCSVEKLIEGHEYQFRICAENKYGVGDPVFTEPAIAKNP 13179
Query: 808 TTAPDAPPDPTVDQVDDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNL-PETA 862
P P + + + V W P +PITGY + + + T++N P
Sbjct: 13180 YDPPGRCDPPVISNITKDHMTVSWKPPADDGGSPITGYLLEKRETQAVNWTKVNRKPIIE 13239
Query: 863 NSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVK 922
++ + LQ G +Y + A+ + P + P + + T
Sbjct: 13240 RTLKATGLQEGTEYEFRVTAINKAGPGKPSDASKAAYARDPQYPPGPPAFPKVYDTTRSS 13299
Query: 923 VTIMWTPPE----SAVTGYRVDVIPVNLPGEHGQRLPIS-RNTFAEVTGLSPGVTYYFKV 977
V++ W P S + GY V+V + LP + + T EVTGL Y F+V
Sbjct: 13300 VSLSWGKPAYDGGSPIIGYLVEVKRADSDNWVRCNLPQNLQKTRFEVTGLMEDTQYQFRV 13359
Query: 978 FAVSHGRESKP-----------LTAQQTTKLDAPTNLQFVNETDST----VLVRWTPPRA 1022
+AV+ S P + +LDA + T V V+ PP
Sbjct: 13360 YAVNKIGYSDPSDVPDKHYPKDILIPPEGELDADLRKTLILRAGVTMRLYVPVKGRPP-P 13418
Query: 1023 QITGYRLTVGLTRR-GQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGV 1081
+IT + V L R G + + + N A +Y ++L G +E V
Sbjct: 13419 KITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKYILTLENSCGKKEYTIVVKV 13478
Query: 1082 FTTLQPGSSIPPYNTEVTETTIVITWTP------APRIGFKLGVRPSQGGEAPREVTSDS 1135
T PG + E+++ + +TW P +P I + + R ++ T S
Sbjct: 13479 LDT--PGPPVNVTVKEISKDSAYVTWEPPIIDGGSPIINYVVQKRDAERKSWSTVTTECS 13536
Query: 1136 -GSIVVSGLTPGVEYVYTIQVLRD------GQERDAPIVNKVVTPLSPPTNLHLEANPDT 1188
S V+ L G Y + + + G+ RDA V TP P +L + + +
Sbjct: 13537 KTSFRVANLEEGKSYFFRVFAENEYGIGDPGETRDA--VKASQTP-GPVVDLKVRSVSKS 13593
Query: 1189 GVLTVSWERSTTPD---ITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNV 1245
++ W++ + I GY + + N + V+ + + +L+ G EY
Sbjct: 13594 S-CSIGWKKPHSDGGSRIIGYVVDFL----TEENKWQRVMKSLSLQYSAKDLTEGKEYTF 13648
Query: 1246 SVYTVKDDKESVPISDTIIP---------EVPQLTDLSFVDITDSSIGLR---------- 1286
V ++ E P T++ ++ L DL ++ +S+ L+
Sbjct: 13649 RVSAENENGEGTPSEITVVARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPIKGKPAPS 13708
Query: 1287 --WTPLNSSTIIGYRITVVAAGEGIP-IFEDFVDSSVGYYTVTGLEPGIDYDISVITLIN 1343
W R++V ++ I D S G YT+T + ++ +
Sbjct: 13709 VSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKEGTISIKVV 13768
Query: 1344 GGESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAPPP---SIDLTNFLVRYSPVKNEE 1400
G PT ++F + + M + WAPP ++TN+++ N +
Sbjct: 13769 GKPGIPT-----------GPIKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDSVNNK 13817
Query: 1401 DVAELSISPSDNAVVLTNLLPGTEYVVSVSS-----VYEQHESTPLRGRQKTGL-DSPTG 1454
V S + +T L G EY VS+ V E +S P+ R + D+P
Sbjct: 13818 WVTCAS-AVQKTTFRVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVPDAPPP 13876
Query: 1455 IDFSDITANSFTVHWIAPRAT----ITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLT 1510
+ D+ +S ++ W P+ T ITGY + + R ++ P +T LT
Sbjct: 13877 PNIVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTPIRMRDFKVTGLT 13936
Query: 1511 PGTEYVVSIVALN----GREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAV-- 1564
G EY ++A+N G+ P D P EV+ T S+ + W P
Sbjct: 13937 EGLEYEFRVMAINLAGVGKPSLPSEPVVALDPIDPPGKPEVINITRNSVTLIWTEPKYDG 13996
Query: 1565 --TVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASS 1622
+ Y + + S ++ V + T++ L G Y + A G A S
Sbjct: 13997 GHKLTGYIVEKRDLPSKSWMKANHVNVPECAFTVTDLVEGGKYEFRIRAKNTAGAISAPS 14056
Query: 1623 KPI-SINYRTEIDKPSQMQVTDVQD------------NSISV--KWLPSSS-PVTGYRVT 1666
+ +I + E + P+ + ++D N+IS+ K LP SS G +
Sbjct: 14057 ESTETIICKDEYEAPTIVLDPTIKDGLTIKAGDTIVLNAISILGKPLPKSSWSKAGKDIR 14116
Query: 1667 TTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRP 1726
P T+ P + +TI+ ++ A NP G V+ V ++ P
Sbjct: 14117 ------PSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFGTKVEHVKVTVLDVPGP 14170
Query: 1727 KG-LAFTDVDVDSIKIAWESP---QGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQG 1782
G + ++V + + W P G + + + + D +
Sbjct: 14171 PGPVEISNVSAEKATLTWTPPLEDGGSPIKSYILEKRETSRLLWTVVSEDIQSCRHVATK 14230
Query: 1783 LRPGSEYTVSVVALH-----DDMESQPLIGTQSTAIPAPTDL-KFTQVTPTSLSAQWTPP 1836
L G+EY V A++ + ++S+P+ P P + + + VT + + W P
Sbjct: 14231 LIQGNEYIFRVSAVNHYGKGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSWKRP 14290
Query: 1837 ----NVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTS 1892
++TGY V K+ ++ I V+GL + YE V A
Sbjct: 14291 VDDGGSEITGYHVERREKKSLRWVRAIKTPVSDLRCKVTGLQEGSTYEFRVSAENRAGIG 14350
Query: 1893 RPAQGVVTTLEN-----VSPPRRARVTDATETTITISWRTKTE----TITGFQVDAVPAN 1943
P++ + L PP VTD T+ + +++W ITG+ V+
Sbjct: 14351 PPSEASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLAWGKPHYDGGLEITGYVVEHQKVG 14410
Query: 1944 GQTPIQRTIKPDVR--SYTITGLQPGTDYKIYLYTLNDNARSSPVVI 1988
+ I+ T +R + + LQ Y + +ND P VI
Sbjct: 14411 DEAWIKDTTGTALRITQFVVPDLQTKEKYNFRISAINDAGVGEPAVI 14457
Score = 136 bits (342), Expect = 3e-31
Identities = 287/1435 (20%), Positives = 516/1435 (35%), Gaps = 196/1435 (13%)
Query: 794 SEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ----APITGYRIVYSPSV 849
+ G +S + P P ++++ ++ W P + IT Y + +
Sbjct: 13067 NSSGSKSATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYIVDKRETS 13126
Query: 850 EGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPS 909
+ +++ S ++ L G +Y I A + PV + P P
Sbjct: 13127 RPNWAQVSATVPITSCSVEKLIEGHEYQFRICAENKYGVGDPVFTEPAIAKNPYDP--PG 13184
Query: 910 PRDLQFVE-VTDVKVTIMWTPPE----SAVTGYRVDVIPVNLPG-EHGQRLPISRNTFAE 963
D + +T +T+ W PP S +TGY ++ R PI T +
Sbjct: 13185 RCDPPVISNITKDHMTVSWKPPADDGGSPITGYLLEKRETQAVNWTKVNRKPIIERTL-K 13243
Query: 964 VTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKL-------DAPTNLQFVNETDSTVLVR 1016
TGL G Y F+V A++ KP A + P + + T S+V +
Sbjct: 13244 ATGLQEGTEYEFRVTAINKAGPGKPSDASKAAYARDPQYPPGPPAFPKVYDTTRSSVSLS 13303
Query: 1017 WTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSVSK--YPLRNLQPASEYTVSLVAIK 1070
W P + I GY + V + N+ ++ K + + L ++Y + A+
Sbjct: 13304 WGKPAYDGGSPIIGYLVEVKRADSDNWVRCNLPQNLQKTRFEVTGLMEDTQYQFRVYAVN 13363
Query: 1071 GNQESPKATGVFTTLQPGSSIPP---YNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEA 1127
S + IPP + ++ +T I+ R G + + G
Sbjct: 13364 KIGYSDPSDVPDKHYPKDILIPPEGELDADLRKTLIL-------RAGVTMRLYVPVKGRP 13416
Query: 1128 PREVTSDSGSIVVS---GLT------------------PGVEYVYTIQVLRDGQERDAPI 1166
P ++T ++ + GL +Y+ T++ +++ I
Sbjct: 13417 PPKITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKYILTLE--NSCGKKEYTI 13474
Query: 1167 VNKVVTPLSPPTNLHL-EANPDTGVLTVSWERSTTPDITG----YRITTTPTNGQQGNSL 1221
V KV+ PP N+ + E + D+ +T WE P I G + ++ +
Sbjct: 13475 VVKVLDTPGPPVNVTVKEISKDSAYVT--WE---PPIIDGGSPIINYVVQKRDAERKSWS 13529
Query: 1222 EEVVHADQSSCTFDNLSPGLEYNVSVYTVKD--------DKESVPISDTIIPEVPQLTDL 1273
++S NL G Y V+ + +++V S T P V DL
Sbjct: 13530 TVTTECSKTSFRVANLEEGKSYFFRVFAENEYGIGDPGETRDAVKASQTPGPVV----DL 13585
Query: 1274 SFVDITDSSIGLRWTPLNS---STIIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEP 1330
++ SS + W +S S IIGY + + ++ + S Y+ L
Sbjct: 13586 KVRSVSKSSCSIGWKKPHSDGGSRIIGYVVDFLTEENK---WQRVMKSLSLQYSAKDLTE 13642
Query: 1331 GIDYDISVITLINGGESAPTTLT---QQTAVPPPTDLRFTNIGPDT-------------M 1374
G +Y V GE P+ +T + V P DL+ PD +
Sbjct: 13643 GKEYTFRVSAENENGEGTPSEITVVARDDVVAPDLDLKGL---PDLCYLAKENSNFRLKI 13699
Query: 1375 RVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLL-------PGTEYVV 1427
+ P PS+ S K E+ +A + +++ V T L+ +Y +
Sbjct: 13700 PIKGKPAPSV---------SWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTI 13750
Query: 1428 SVSSVYEQHEST-PLRGRQKTGLDSPTG-IDFSDITANSFTVHWIAPR----ATITGYRI 1481
++ +V E T ++ K G+ PTG I F ++TA + T+ W P+ + IT Y I
Sbjct: 13751 TLKNVAGTKEGTISIKVVGKPGI--PTGPIKFDEVTAEAMTLKWAPPKDDGGSEITNY-I 13807
Query: 1482 RHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN------GREESPLLIGQQ 1535
+ + + + + +T L G EY + A N G + P++
Sbjct: 13808 LEKRDSVNNKWVTCASAVQKTTFRVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHP 13867
Query: 1536 STVSDVPRDLEVVAATPTSLLISWDAPAVT----VRYYRITYGETGGNSPVQEFTVPGSK 1591
V D P +V S+ ++W P T + Y + + E + P
Sbjct: 13868 FDVPDAPPPPNIVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTPIRM 13927
Query: 1592 STATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISV 1651
++GL G++Y V A+ G S + ID P + +V ++ NS+++
Sbjct: 13928 RDFKVTGLTEGLEYEFRVMAINLAGVGKPSLPSEPVVALDPIDPPGKPEVINITRNSVTL 13987
Query: 1652 KWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQN 1707
W +TGY V K + T+ L +Y + A+N
Sbjct: 13988 IWTEPKYDGGHKLTGYIVEKRDLPSKSWMKANHVNVPECAFTVTDLVEGGKYEFRIRAKN 14047
Query: 1708 PSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQV----------------S 1751
+G ++ T I + + A T V +IK G S
Sbjct: 14048 TAGAISAPSESTETIICKDEYEAPTIVLDPTIKDGLTIKAGDTIVLNAISILGKPLPKSS 14107
Query: 1752 RYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQST 1811
+ I ++ P T + + EYT++ +
Sbjct: 14108 WSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFGTKVEHVKVTVLDV 14167
Query: 1812 AIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVR--VTPKEKTGPMKEINLAPDSSSV- 1868
P P ++ + V+ + WTPP ++ G ++ + K +T + ++ D S
Sbjct: 14168 PGP-PGPVEISNVSAEKATLTWTPP-LEDGGSPIKSYILEKRETSRLLWTVVSEDIQSCR 14225
Query: 1869 -VVSGLMVATKYEVSVYALKDTLTSRPAQG----VVTTLENVSPPRRARVTDATETTITI 1923
V + L+ +Y V A+ P Q +V PP + V++ T+ T T+
Sbjct: 14226 HVATKLIQGNEYIFRVSAVNHYGKGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTATV 14285
Query: 1924 SWRTKTE----TITGFQVDAVPANGQTPIQRTIKPDVRSY--TITGLQPGTDYKIYLYTL 1977
SW+ + ITG+ V+ + R IK V +TGLQ G+ Y+ +
Sbjct: 14286 SWKRPVDDGGSEITGYHVERREKKSLRWV-RAIKTPVSDLRCKVTGLQEGSTYEFRVSAE 14344
Query: 1978 N-------DNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYII 2026
N A S ++ DA+ PSN TT S ++W P ITGY++
Sbjct: 14345 NRAGIGPPSEASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLAWGKPHYDGGLEITGYVV 14404
Query: 2027 KYEKPGSPPREVVPRPRPG----VTEATITGLEPGTEYTIYVIALKNNQKSEPLI 2077
+++K G E + G +T+ + L+ +Y + A+ + EP +
Sbjct: 14405 EHQKVGD---EAWIKDTTGTALRITQFVVPDLQTKEKYNFRISAINDAGVGEPAV 14456
Score = 134 bits (338), Expect = 9e-31
Identities = 378/1880 (20%), Positives = 675/1880 (35%), Gaps = 278/1880 (14%)
Query: 628 IQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISI 684
+ W P S I+ Y+L R +V K P + GL+ G YE ++ +I
Sbjct: 13201 VSWKPPADDGGSPITGYLLEKRETQAVNWTKVNRKPIIERTLKATGLQEGTEYEFRVTAI 13260
Query: 685 QQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSW---- 740
+ G + + S + P V + T SS +SW
Sbjct: 13261 NKAGPGKPSD------------ASKAAYARDPQYPPGPPAFPKVYDTTRSSVSLSWGKPA 13308
Query: 741 VSASDTVSGFRVEYELSEEGDEPQYLDLPST--ATSVNIPDLLPGRKYIVNVYQISEDGE 798
+ G+ VE + + + D +LP T + L+ +Y VY +++ G
Sbjct: 13309 YDGGSPIIGYLVEVKRA-DSDNWVRCNLPQNLQKTRFEVTGLMEDTQYQFRVYAVNKIG- 13366
Query: 799 QSLILSTSQTTAPD--------APPDPTVDQVDDTSIVVR---WSRPQAPITGYRIVYSP 847
+ + PD PP+ +D ++++R R P+ G P
Sbjct: 13367 -----YSDPSDVPDKHYPKDILIPPEGELDADLRKTLILRAGVTMRLYVPVKGRP---PP 13418
Query: 848 SVEGSSTELNLPETAN-SVTLSDLQPGV-----------QYNITIYAVEENQESTPVVIQ 895
+ S +NL + + +D + +Y +T+ +E T VV
Sbjct: 13419 KITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKYILTLENSCGKKEYTIVVKV 13478
Query: 896 QETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPGEHG 951
+T G P + TV E++ + W PP S + Y V
Sbjct: 13479 LDTPGPPVNVTVK--------EISKDSAYVTWEPPIIDGGSPIINYVVQKRDAERKSWST 13530
Query: 952 QRLPISRNTFAEVTGLSPGVTYYFKVFAVSH---GRESKPLTAQQTTKLDAP-TNLQFVN 1007
S+ +F V L G +Y+F+VFA + G + A + ++ P +L+ +
Sbjct: 13531 VTTECSKTSF-RVANLEEGKSYFFRVFAENEYGIGDPGETRDAVKASQTPGPVVDLKVRS 13589
Query: 1008 ETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYT 1063
+ S+ + W P ++I GY + LT + ++ S+ +Y ++L EYT
Sbjct: 13590 VSKSSCSIGWKKPHSDGGSRIIGYVVDF-LTEENKWQRVMKSLSL-QYSAKDLTEGKEYT 13647
Query: 1064 VSLVAIKGNQE-SPKATGVFT---TLQPG---SSIPPYNTEVTETT-----IVITWTPAP 1111
+ A N E +P V + P +P E + I I PAP
Sbjct: 13648 FRVSAENENGEGTPSEITVVARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPIKGKPAP 13707
Query: 1112 RIGFKLGVRP-SQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKV 1170
+ +K G P + E ++ + +++V YTI + ++ I KV
Sbjct: 13708 SVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKEGTISIKV 13767
Query: 1171 VTPLSPPTNLHLEANPDTGVLTVSW---ERSTTPDITGYRITTTPTNGQQGNSLEEVVHA 1227
V PT +T+ W + +IT Y + + + + V
Sbjct: 13768 VGKPGIPTGPIKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDSVNNKWVTCASAV-- 13825
Query: 1228 DQSSCTFDNLSPGLEYNVSV-----YTVKDDKESVPI---SDTIIPEVPQLTDLSFVDIT 1279
+++ L G+EY V Y V + +S PI +P+ P ++ VD+
Sbjct: 13826 QKTTFRVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVPDAPPPPNI--VDVR 13883
Query: 1280 DSSIGLRWT---PLNSSTIIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDI 1336
S+ L WT S I GY + + + + + VTGL G++Y+
Sbjct: 13884 HDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTPIRMRDFKVTGLTEGLEYEF 13943
Query: 1337 SVITLINGGESAPTTLTQQTA----VPPPTDLRFTNIGPDTMRVTWAPPP---SIDLTNF 1389
V+ + G P+ ++ + PP NI +++ + W P LT +
Sbjct: 13944 RVMAINLAGVGKPSLPSEPVVALDPIDPPGKPEVINITRNSVTLIWTEPKYDGGHKLTGY 14003
Query: 1390 LVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEY---------VVSVSSVYEQHESTP 1440
+V + ++ + ++ + A +T+L+ G +Y ++S+ E E+
Sbjct: 14004 IVEKRDLPSKSWMKANHVNVPECAFTVTDLVEGGKYEFRIRAKNTAGAISAPSESTETII 14063
Query: 1441 LRGRQK--TGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVP 1498
+ + T + PT D I A V +I G + P+ + +D P
Sbjct: 14064 CKDEYEAPTIVLDPTIKDGLTIKAGDTIV---LNAISILGKPL---PKSSWSKAGKDIRP 14117
Query: 1499 HSRNSITLTNLT-----------PGTEYVVSIVALNGREESPLLIGQQSTVSDV---PRD 1544
IT T + EY ++ G + + + TV DV P
Sbjct: 14118 SDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFGTKVEHVKV----TVLDVPGPPGP 14173
Query: 1545 LEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATI-------- 1596
+E+ + ++W P E GG SP++ + + +++ +
Sbjct: 14174 VEISNVSAEKATLTWTPPL-----------EDGG-SPIKSYILEKRETSRLLWTVVSEDI 14221
Query: 1597 -------SGLKPGVDYTITVYAVT--GRGDSPASSKPISINYR-TEIDKPSQMQVTDVQD 1646
+ L G +Y V AV G+G+ P S+P+ + R P + +V++V
Sbjct: 14222 QSCRHVATKLIQGNEYIFRVSAVNHYGKGE-PVQSEPVKMVDRFGPPGPPEKPEVSNVTK 14280
Query: 1647 NSISVKWL----PSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVS 1702
N+ +V W S +TGY V K + + GLQ Y
Sbjct: 14281 NTATVSWKRPVDDGGSEITGYHVERREKKSLRWVRAIKTPVSDLRCKVTGLQEGSTYEFR 14340
Query: 1703 VYAQNPSGESQP-------LVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQG----QVS 1751
V A+N +G P L++ A P TD S +AW P +++
Sbjct: 14341 VSAENRAGIGPPSEASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLAWGKPHYDGGLEIT 14400
Query: 1752 RYRVTYSSPEDGIHELFPAPDGEEDTA-ELQGLRPGSEYTVSVVALHDDMESQPLIGTQS 1810
Y V + D T + L+ +Y + A++D +P +
Sbjct: 14401 GYVVEHQKVGDEAWIKDTTGTALRITQFVVPDLQTKEKYNFRISAINDAGVGEPAV---- 14456
Query: 1811 TAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPD------ 1864
IP ++ L A+ V G +R+ K P E+ D
Sbjct: 14457 --IPDVEIVEREMAPDFELDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKN 14514
Query: 1865 ------SSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVT--TLENVSPPRRARVTDA 1916
+ S + + +Y+ + + + G V L+ P R TD
Sbjct: 14515 RANIENTESFTLLIIPECNRYDTGKFVMTIENPAGKKSGFVNVRVLDTPGPVLNLRPTDI 14574
Query: 1917 TETTITISWRTKT----ETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKI 1972
T+ ++T+ W IT + V+ A ++ T K +Y +TGL G +Y
Sbjct: 14575 TKDSVTLHWDLPLIDGGSRITNYIVEKREATRKSYSTATTKCHKCTYKVTGLSEGCEYFF 14634
Query: 1973 YLYTLNDNARSSPV----VIDASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGY 2024
+ N+ P + AS A P +L + T +++ ++W P+ ++ITGY
Sbjct: 14635 RVMAENEYGIGEPTETTEPVKASEAPSPPDSLNIMDITKSTVSLAWPKPKHDGGSKITGY 14694
Query: 2025 IIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDE 2084
+I+ ++ GS + + E + L G EYT V+A+ + +S P R
Sbjct: 14695 VIEAQRKGSDQWTHITTVKG--LECVVRNLTEGEEYTFQVMAVNSAGRSAPRESRPVI-- 14750
Query: 2085 LPQLVTLPHPNLHGPEILDVPSTVQKTPFVTHPGYDTGNGIQLPGTSGQQPSV----GQQ 2140
+ + LP +L G + + + G + +++P +P+V G Q
Sbjct: 14751 VKEQTMLPELDLRG---------IYQKLVIAKAGDNI--KVEIPVLGRPKPTVTWKKGDQ 14799
Query: 2141 MIFEEHGFRRTTPPTTATP--------IRHRPRPYPPN----VGEEIQIGHIPREDVDYH 2188
++ + +R TTAT +R PYP VGE + I D+
Sbjct: 14800 ILKQT---QRVNFETTATSTILNINECVRSDSGPYPLTARNIVGEVGDVITIQVHDIP-- 14854
Query: 2189 LYPHGPGLNPNASTGQEALSQTTISWAPFQDTSEYIISCHPV---GTDEEP-LQFRVPGT 2244
GP P + + T SW P ++ IS + V TD ++
Sbjct: 14855 ----GPPTGP-IKFDEVSSDFVTFSWDPPENDGGVPISNYVVEMRQTDSTTWVELATTVI 14909
Query: 2245 STSATLTGLTRGATYNIIVEALKDQQRHKVREEVVTVGNSVNEGLNQPTDDSCFDPYTVS 2304
T+ T LT G Y V+A Q R+ V + + N P V+
Sbjct: 14910 RTTYKATRLTTGLEYQFRVKA---QNRYGVGPGITSACIVANYPFKVPGPPGTPQVTAVT 14966
Query: 2305 HYAVGDEW-ERMSESGFKLL 2323
++ W E +S+ G +L
Sbjct: 14967 KDSMTISWHEPLSDGGSPIL 14986
Score = 128 bits (322), Expect = 6e-29
Identities = 343/1604 (21%), Positives = 574/1604 (35%), Gaps = 260/1604 (16%)
Query: 611 PVEVFITETPSQPNSHPIQWNAPQ---PSHISKYILRWRPKNSVGRWKEATIPGHLNS-- 665
P ++ I + S +S + W+ P S ++ Y++ R + W + G + +
Sbjct: 20865 PAKIRIAD--STKSSITLGWSKPVYDGGSAVTGYVVEIR-QGEEEEWTTVSTKGEVRTTE 20921
Query: 666 YTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATS 725
Y + LKPGV Y ++ ++ G E + + S +
Sbjct: 20922 YVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQAKDILEAPEIDLDVALRTSVIAKAG 20981
Query: 726 ESVTEITASSF----VVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLL 781
E V + V+W + G Y + E D L +P +
Sbjct: 20982 EDVQVLIPFKGRPPPTVTWRKDEKNL-GSDARYSI-ENTDSSSLLTIPQVTRNDT----- 21034
Query: 782 PGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ----AP 837
KYI+ + + + S + S P A V V ++ + W P +P
Sbjct: 21035 --GKYILTIENGVGEPKSSTV-SVKVLDTPAACQKLQVKHVSRGTVTLLWDPPLIDGGSP 21091
Query: 838 ITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQE 897
I Y I + + + + ++ ++ S L DL + + A E P E
Sbjct: 21092 IINYVIEKRDATKRTWSVVSHKCSSTSFKLIDLSEKTPFFFRVLAENEIGIGEPC----E 21147
Query: 898 TTGTPRSDTVPSP-RDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPVNLPGEHG- 951
TT ++ VP+P RDL + T V + WT P+ S +T Y V+ GE
Sbjct: 21148 TTEPVKAAEVPAPIRDLSMKDSTKTSVILSWTKPDFDGGSVITEY---VVERKGKGEQTW 21204
Query: 952 QRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDS 1011
IS+ EV+ L F+VFA + S P+T T + L E D
Sbjct: 21205 SHAGISKTCEIEVSQLKEQSVLEFRVFAKNEKGLSDPVTIGPITVKE----LIITPEVDL 21260
Query: 1012 TVLVRWTPPRAQIT---GYRLTVGLTRRGQPRQYNVGPSVS----KYPLRNLQ------P 1058
+ + P AQ+T G+ + + L +G+P+ PS+S PL+ +
Sbjct: 21261 SDI-----PGAQVTVRIGHNVHLELPYKGKPK-----PSISWLKDGLPLKESEFVRFSKT 21310
Query: 1059 ASEYTVSLVAIKGNQESPKATGVFT-------------TLQPGSSI--PPYNTEVTETTI 1103
++ T+S+ K + K T + TL P S P E+ ++
Sbjct: 21311 ENKITLSIKNAK-KEHGGKYTVILDNAVCRIAVPITVITLGPPSKPKGPIRFDEIKADSV 21369
Query: 1104 VITWTPAPRIGFKLGVRPSQGGEAP------REVTSDSGSIVVSG----------LTPGV 1147
+++W G GGE RE + + +V S L
Sbjct: 21370 ILSWDVPEDNG---------GGEITCYSIEKRETSQTNWKMVCSSVARTTFKVPNLVKDA 21420
Query: 1148 EYVYTIQVLRDGQERDAPIVNKVVTP-----LSPPTNLHLEANPDTGVLTVSWERSTTP- 1201
EY + ++ + P+V+ ++ + P + N + ++++W+
Sbjct: 21421 EYQFRVRA-ENRYGVSQPLVSSIIVAKHQFRIPGPPGKPVIYNVTSDGMSLTWDAPVYDG 21479
Query: 1202 --DITGYRITTTPTNG---QQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKES 1256
++TG+ + N Q+ N+ + + T L GL+Y VY S
Sbjct: 21480 GSEVTGFHVEKKERNSILWQKVNT--SPISGREYRAT--GLVEGLDYQFRVYAENSAGLS 21535
Query: 1257 VPISDT-----IIPEVPQLTDLSFVDITDSSIGLRWTPL---NSSTIIGYRITVVAAGEG 1308
P + + P P T ++D+T +I L+W P S I+GY I E
Sbjct: 21536 SPSDPSKFTLAVSPVDPPGTP-DYIDVTRETITLKWNPPLRDGGSKIVGYSIEKRQGNER 21594
Query: 1309 IPIFEDFVDSSVGYYTVTGLEPGIDYDISVI------TLINGGESAPTTLTQQTAVPPPT 1362
+ +F D S YTVTGL PG Y+ +I T+ +S+ +T+ VPP
Sbjct: 21595 W-VRCNFTDVSECQYTVTGLSPGDRYEFRIIARNAVGTISPPSQSSGIIMTRDENVPP-- 21651
Query: 1363 DLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNE---EDVAELSISPSDNAVVLTNL 1419
GP+ LV+ PV +D E+ + + +T++
Sbjct: 21652 ---IVEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMN---MEITDV 21705
Query: 1420 LPGTEYVV--------SVSSVYEQHESTPLRGRQKTGLDSPTG-----IDFSDITANSFT 1466
L T V V +V ++ S + K + G I F++IT T
Sbjct: 21706 LGSTSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQDTPGKVVGPIRFTNITGEKMT 21765
Query: 1467 VHWIAPR----ATITGYRI-RHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVA 1521
+ W AP A IT Y I + + ED+ S T L G EY + A
Sbjct: 21766 LWWDAPLNDGCAPITHYIIEKRETSRLAWALIEDKC--EAQSYTAIKLINGNEYQFRVSA 21823
Query: 1522 LN----GR--EESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGE 1575
+N GR + P++ Q TV D P E T S+ ++W P E
Sbjct: 21824 VNKFGVGRPLDSDPVVAQIQYTVPDAPGIPEPSNITGNSITLTWARP------------E 21871
Query: 1576 TGGNSPVQEFTV-----------------PGSKSTATISGLKPGVDYTITVYAVTGRGDS 1618
+ G S +Q++ + P S++ ++GL G +Y V A G
Sbjct: 21872 SDGGSEIQQYILERREKKSTRWVKVISKRPISETRFKVTGLTEGNEYEFHVMAENAAGVG 21931
Query: 1619 PASSKPISINYRTEIDKPSQ---MQVTDVQDNSISVKW----LPSSSPVTGYRVTTTPKN 1671
PAS I R ++ P ++VTD ++S++W + GY + +
Sbjct: 21932 PASGISRLIKCREPVNPPGPPTVVKVTDTSKTTVSLEWSKPVFDGGMEIIGYIIEMCKAD 21991
Query: 1672 GPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTA-VTNIDRPKGLA 1730
K +T T+ LQ EY V A N +G+ T + +DR L
Sbjct: 21992 LGDWHKVNAEACVKTRYTVTDLQAGEEYKFRVSAINGAGKGDSCEVTGTIKAVDR---LT 22048
Query: 1731 FTDVDVDS-IKIAWESPQGQVSRYRVTY----------SSPEDGIH---ELFPAPDGEED 1776
++D+D+ K G R + Y S P+ + ++
Sbjct: 22049 APELDIDANFKQTHVVRAGASIRLFIAYQGRPTPTAVWSKPDSNLSLRADIHTTDSFSTL 22108
Query: 1777 TAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPP 1836
T E +YT++V + T P P + F VT S + W P
Sbjct: 22109 TVENCNRNDAGKYTLTVENNSGSKSITFTVKVLDTPGP-PGPITFKDVTRGSATLMWDAP 22167
Query: 1837 NVQLTGYRVRVTPKEKTGPMKE----INLAPDSSSVVVSGLMVATKYEVSVYALKDTLTS 1892
+ G R+ EK + I+ V+ L Y V A+ +
Sbjct: 22168 LLD-GGARIHHYVVEKREASRRSWQVISEKCTRQIFKVNDLAEGVPYYFRVSAVNEYGVG 22226
Query: 1893 RPAQ--GVVTTLENVSPPRRARVTDATETTITISW----RTKTETITGFQVDAVPANGQT 1946
P + + E +PPRR V D ++++ ++W ITG+ ++
Sbjct: 22227 EPYEMPEPIVATEQPAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSDF 22286
Query: 1947 PIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATT 2006
++ + ++T+ L T+Y+ + ND S P +S I P
Sbjct: 22287 WVEAGHTKQL-TFTVERLVEKTEYEFRVKAKNDAGYSEPREAFSSVIIKEPQ------IE 22339
Query: 2007 PNSLLVSWQPPRARITGYIIKYEKPGSPPREVVP---RPRPGVT 2047
P + L IT +I K GSP VP RP P VT
Sbjct: 22340 PTADLTG-------ITNQLITC-KAGSPFTIDVPISGRPAPKVT 22375
Score = 124 bits (311), Expect = 1e-27
Identities = 291/1338 (21%), Positives = 513/1338 (38%), Gaps = 174/1338 (13%)
Query: 780 LLPGRKYI-----VNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRP 834
++ G +YI VN Y I E E +++ + P P P V ++ S+ V WSRP
Sbjct: 20725 IIKGNEYIFRVRAVNKYGIGEPLESDSVVAKNAFVTPGPPGIPEVTKITKNSMTVVWSRP 20784
Query: 835 QA----PITGYRIVYSPSVEGSSTEL---NLPETANSVTLSDLQPGVQYNI-TIYAVEEN 886
A I+GY + ++ + +T VT QY + + A +
Sbjct: 20785 IADGGSDISGYFLEKRDKKSLGWFKVLKETIRDTRQKVTGLTENSDYQYRVCAVNAAGQG 20844
Query: 887 QESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVI 942
S P + D P ++ + T +T+ W+ P SAVTGY V++
Sbjct: 20845 PFSEP---SEFYKAADPIDPPGPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVVEI- 20900
Query: 943 PVNLPGEHGQRLPIS-----RNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTK- 996
GE + +S R T V+ L PGV YYF+V AV+ + +P+ + +
Sbjct: 20901 ---RQGEEEEWTTVSTKGEVRTTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQA 20957
Query: 997 ---LDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQP--------RQYNVG 1045
L+AP E D V +R T A+ G + V + +G+P + N+G
Sbjct: 20958 KDILEAP-------EIDLDVALR-TSVIAK-AGEDVQVLIPFKGRPPPTVTWRKDEKNLG 21008
Query: 1046 PSVSKYPLRNLQPASEYTVS----------LVAIKGNQESPKATGVFTTL--QPGSSIPP 1093
S ++Y + N +S T+ ++ I+ PK++ V + P +
Sbjct: 21009 -SDARYSIENTDSSSLLTIPQVTRNDTGKYILTIENGVGEPKSSTVSVKVLDTPAACQKL 21067
Query: 1094 YNTEVTETTIVITWTP------APRIGFKLGVRPS---QGGEAPREVTSDSGSIV-VSGL 1143
V+ T+ + W P +P I + + R + + +S S ++ +S
Sbjct: 21068 QVKHVSRGTVTLLWDPPLIDGGSPIINYVIEKRDATKRTWSVVSHKCSSTSFKLIDLSEK 21127
Query: 1144 TPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDI 1203
TP V + G+ + K +P +L ++ + T V+ +SW T PD
Sbjct: 21128 TPFFFRVLAENEIGIGEPCETTEPVKAAEVPAPIRDLSMKDSTKTSVI-LSW---TKPDF 21183
Query: 1204 TGYRITTTPTNGQQGNSLEEVVHADQS-SCTFD----NLSPGLEYNVSVYTVKDDKESVP 1258
G + T ++G + HA S +C + LE+ V K + V
Sbjct: 21184 DGGSVITEYVVERKGKGEQTWSHAGISKTCEIEVSQLKEQSVLEFRVFAKNEKGLSDPVT 21243
Query: 1259 ISDTIIPEVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGY----RITVVAAGEGIPIFE- 1313
I + E+ ++ DI + + +R N + Y + ++ +G+P+ E
Sbjct: 21244 IGPITVKELIITPEVDLSDIPGAQVTVR-IGHNVHLELPYKGKPKPSISWLKDGLPLKES 21302
Query: 1314 DFVDSSVGYYTVT------GLEPGIDYDISVITLINGGESAPTTLTQQTAVPPPTDLRFT 1367
+FV S +T E G Y + + + T +T P +RF
Sbjct: 21303 EFVRFSKTENKITLSIKNAKKEHGGKYTVILDNAVCRIAVPITVITLGPPSKPKGPIRFD 21362
Query: 1368 NIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSI---SPSDNAVVLTNLLPGTE 1424
I D++ ++W P + + YS K E + S + + NL+ E
Sbjct: 21363 EIKADSVILSWDVPED-NGGGEITCYSIEKRETSQTNWKMVCSSVARTTFKVPNLVKDAE 21421
Query: 1425 YVVSVSSVYEQHESTPL-----RGRQKTGLDSPTGID-FSDITANSFTVHWIAP----RA 1474
Y V + S PL + + + P G ++T++ ++ W AP +
Sbjct: 21422 YQFRVRAENRYGVSQPLVSSIIVAKHQFRIPGPPGKPVIYNVTSDGMSLTWDAPVYDGGS 21481
Query: 1475 TITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQ 1534
+TG+ + + + + P S T L G +Y + A N S
Sbjct: 21482 EVTGFHVEKKERNSILWQKVNTSPISGREYRATGLVEGLDYQFRVYAENSAGLSSPSDPS 21541
Query: 1535 QSTVS----DVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYG---ETGGNSPVQEFTV 1587
+ T++ D P + + T ++ + W+ P + Y G V+
Sbjct: 21542 KFTLAVSPVDPPGTPDYIDVTRETITLKWNPPLRDGGSKIVGYSIEKRQGNERWVRCNFT 21601
Query: 1588 PGSKSTATISGLKPGVDYTITVYAVTGRGD-SPASSKPISINYRTEIDKPSQMQVTDVQD 1646
S+ T++GL PG Y + A G SP S I R E P + D
Sbjct: 21602 DVSECQYTVTGLSPGDRYEFRIIARNAVGTISPPSQSSGIIMTRDENVPPIVEFGPEYFD 21661
Query: 1647 -------NSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTK----TAGPDQTEMTIEGLQP 1695
S+ +K L PV RVT K+G K T T + +
Sbjct: 21662 GLIIKSGESLRIKALVQGRPVP--RVTWF-KDGVEIEKRMNMEITDVLGSTSLFVRDATR 21718
Query: 1696 TVEYVVSVYAQNPSGESQPLVQTAVTNIDRP----KGLAFTDVDVDSIKIAWESPQGQ-- 1749
V +V A+N SG ++ ++ V D P + FT++ + + + W++P
Sbjct: 21719 DHRGVYTVEAKNASGSAKAEIKVKVQ--DTPGKVVGPIRFTNITGEKMTLWWDAPLNDGC 21776
Query: 1750 --VSRYRVTYSSPEDGIHELFPAPDGEEDTAELQG-----LRPGSEYTVSVVALHD---- 1798
++ Y + L ED E Q L G+EY V A++
Sbjct: 21777 APITHYIIEKRETSRLAWALI------EDKCEAQSYTAIKLINGNEYQFRVSAVNKFGVG 21830
Query: 1799 -DMESQPLIGTQSTAIP-APTDLKFTQVTPTSLSAQWTPP----NVQLTGYRVRVTPKEK 1852
++S P++ +P AP + + +T S++ W P ++ Y + K+
Sbjct: 21831 RPLDSDPVVAQIQYTVPDAPGIPEPSNITGNSITLTWARPESDGGSEIQQYILERREKKS 21890
Query: 1853 TGPMKEINLAPDSSS-VVVSGLMVATKYEVSVYALKDTLTSRPAQGV---VTTLENVS-- 1906
T +K I+ P S + V+GL +YE V A ++ PA G+ + E V+
Sbjct: 21891 TRWVKVISKRPISETRFKVTGLTEGNEYEFHVMA-ENAAGVGPASGISRLIKCREPVNPP 21949
Query: 1907 -PPRRARVTDATETTITISWRTKT----ETITGFQVDAVPANGQTPIQRTIKPDVRS-YT 1960
PP +VTD ++TT+++ W I G+ ++ A+ + + V++ YT
Sbjct: 21950 GPPTVVKVTDTSKTTVSLEWSKPVFDGGMEIIGYIIEMCKADLGDWHKVNAEACVKTRYT 22009
Query: 1961 ITGLQPGTDYKIYLYTLN 1978
+T LQ G +YK + +N
Sbjct: 22010 VTDLQAGEEYKFRVSAIN 22027
Score = 124 bits (310), Expect = 2e-27
Identities = 338/1629 (20%), Positives = 573/1629 (35%), Gaps = 196/1629 (12%)
Query: 624 NSHPIQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNS--YTIKGLKPGVVYE 678
NS + W P+ S I +YIL R K S RW + ++ + + GL G YE
Sbjct: 21861 NSITLTWARPESDGGSEIQQYILERREKKST-RWVKVISKRPISETRFKVTGLTEGNEYE 21919
Query: 679 GQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVV 738
+++ G + PV P P V VT+ + ++ +
Sbjct: 21920 FHVMAENAAGVGPASGIS-RLIKCREPVNP--------PGPPTVV---KVTDTSKTTVSL 21967
Query: 739 SW----VSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQIS 794
W + G+ +E ++ GD + T + DL G +Y V I+
Sbjct: 21968 EWSKPVFDGGMEIIGYIIEMCKADLGDWHKVNAEACVKTRYTVTDLQAGEEYKFRVSAIN 22027
Query: 795 EDGEQSLILSTSQTTAPD--APPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGS 852
G+ T A D P+ +D + VVR Y+ +P+ S
Sbjct: 22028 GAGKGDSCEVTGTIKAVDRLTAPELDIDANFKQTHVVRAGASIRLFIAYQGRPTPTAVWS 22087
Query: 853 STELNLPETANSVTLSDLQPGVQYNIT-------IYAVEENQESTPVVIQQETTGTPRSD 905
+ NL A+ T N VE N S + + TP
Sbjct: 22088 KPDSNLSLRADIHTTDSFSTLTVENCNRNDAGKYTLTVENNSGSKSITFTVKVLDTPGP- 22146
Query: 906 TVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPGEHGQRLPISRNTF 961
P + F +VT T+MW P + + Y V+ + +R F
Sbjct: 22147 ----PGPITFKDVTRGSATLMWDAPLLDGGARIHHYVVEKREASRRSWQVISEKCTRQIF 22202
Query: 962 AEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQ----TTKLDAPTNLQFVNETDSTVLVRW 1017
+V L+ GV YYF+V AV+ +P + T + P L V+ + S+ ++ W
Sbjct: 22203 -KVNDLAEGVPYYFRVSAVNEYGVGEPYEMPEPIVATEQPAPPRRLDVVDTSKSSAVLAW 22261
Query: 1018 TPP----RAQITGYRLTVGLTRRGQPRQYNVGPSVS-KYPLRNLQPASEY---------- 1062
P ++ITGY L + ++G G + + + L +EY
Sbjct: 22262 LKPDHDGGSRITGYLLE--MRQKGSDFWVEAGHTKQLTFTVERLVEKTEYEFRVKAKNDA 22319
Query: 1063 -------TVSLVAIKGNQESPKA--TGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRI 1113
S V IK Q P A TG+ L + P+ +V I+ PAP++
Sbjct: 22320 GYSEPREAFSSVIIKEPQIEPTADLTGITNQLITCKAGSPFTIDVP-----ISGRPAPKV 22374
Query: 1114 GFKL-GVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVT 1172
+KL +R + T D ++ V G Y + + + + V+
Sbjct: 22375 TWKLEEMRLKETDRVSITTTKDRTTLTVKDSMRGDSGRYFLTLENTAGVKTFSVTVVVIG 22434
Query: 1173 PLSPPTNLHLEANPDTGVLTVSW---ERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQ 1229
P T ++ +SW + +IT Y + + + V Q
Sbjct: 22435 RPGPVTGPIEVSSVSAESCVLSWGEPKDGGGTEITNYIVEKRESGTTAWQLVNSSVKRTQ 22494
Query: 1230 SSCTFDNLSPGLEYNVSV-----YTVKDDKESVPI---SDTIIPEVPQLTDLSFVDITDS 1281
T +L+ +EY+ V + V ES PI + P P T ++ +
Sbjct: 22495 IKVT--HLTKYMEYSFRVSSENRFGVSKPLESAPIIAEHPFVPPSAP--TRPEVYHVSAN 22550
Query: 1282 SIGLRWTPL---NSSTIIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISV 1338
++ +RW S IIGY + + + E+ V Y VTGL G++Y
Sbjct: 22551 AMSIRWEEPYHDGGSKIIGYWVEKKERNTILWVKENKVPCLECNYKVTGLVEGLEYQFRT 22610
Query: 1339 ITLINGGES----APTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAPPP---SIDLTNFLV 1391
L G S A + Q V P T++ T+ + W+ P + +++
Sbjct: 22611 YALNAAGVSKASEASRPIMAQNPVDAPGRPEVTDVTRSTVSLIWSAPAYDGGSKVVGYII 22670
Query: 1392 RYSPVKNEEDVAELSIS---PSDNAVVLTNLLPGTEYVVSVSS------VYEQHEST-PL 1441
PV D L + SDN +T L G Y V + + + EST P+
Sbjct: 22671 ERKPVSEVGDGRWLKCNYTIVSDNFFTVTALSEGDTYEFRVLAKNAAGVISKGSESTGPV 22730
Query: 1442 RGRQ-----KTGLDSPTGIDFSDITANSFTVHWIA----PRATITGYRIRHHPEHFSGRP 1492
R K LD+ D I A S V A P I + +
Sbjct: 22731 TCRDEYAPPKAELDARLHGDLVTIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVS 22790
Query: 1493 REDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVP---RDLEVVA 1549
+ + I + + +Y +++ +G + +++ V D P L V
Sbjct: 22791 LQYTGKRATAVIKFCDRSDSGKYTLTVKNASGTKAVSVMV----KVLDSPGPCGKLTVSR 22846
Query: 1550 ATPTSLLISWDAP----AVTVRYYRITYGETGGNSPVQEFTVPGSKSTAT--ISGLKPGV 1603
T ++W P + +Y + ET S + V G T + ++ L
Sbjct: 22847 VTQEKCTLAWSLPQEDGGAEITHYIVERRET---SRLNWVIVEGECPTLSYVVTRLIKNN 22903
Query: 1604 DYTITVYAVTGRGDS-PASSKPI-SINYRTEIDKPSQMQVTDVQDNSISVKWLPSSS--- 1658
+Y V AV G P S+PI + N T P + I ++W S
Sbjct: 22904 EYIFRVRAVNKYGPGVPVESEPIVARNSFTIPSPPGIPEEVGTGKEHIIIQWTKPESDGG 22963
Query: 1659 -PVTGYRVTTTPKNGPGPTK-TKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLV 1716
++ Y V K T+ K T + + L +Y V A N +G S+P
Sbjct: 22964 NEISNYLVDKREKKSLRWTRVNKDYVVYDTRLKVTSLMEGCDYQFRVTAVNAAGNSEPSE 23023
Query: 1717 QTAVTNIDR-------PKGLAFTDVDVDSIKIAWESPQGQVSRYRVTY-----SSPEDGI 1764
+ + P D SI +AW P V Y D
Sbjct: 23024 ASNFISCREPSYTPGPPSAPRVVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDTDQW 23083
Query: 1765 HELFPAPDGEEDTAELQGLRPGSEYTVSVVALH---------DDMESQPLIGTQSTAIPA 1815
+ + + L+ G +Y+ V A++ E +P+ + +
Sbjct: 23084 YRVHTNATIRNTEFTVPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEIPDLEL 23143
Query: 1816 PTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTG---PMKEINLAPDSSSVVVSG 1872
DLK T S + V ++G V K G + I +S S+++
Sbjct: 23144 ADDLKKTVTIRAGASLRLM---VSVSGRPPPVITWSKQGIDLASRAIIDTTESYSLLI-- 23198
Query: 1873 LMVATKYEVSVYALKDTLTS--RPAQGVVTTLENVSPPRRARVTDATETTITISWRTKT- 1929
+ +Y+ Y ++ S + A +V + P +V + + ++TI+W T
Sbjct: 23199 VDKVNRYDAGKYTIEAENQSGKKSATVLVKVYDTPGPCPSVKVKEVSRDSVTITWEIPTI 23258
Query: 1930 ---ETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKI-----YLYTLNDNA 1981
+ + V+ A + T K Y I+GL GT Y +Y + +
Sbjct: 23259 DGGAPVNNYIVEKREAAMRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYGIGEPC 23318
Query: 1982 RSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPP----RARITGYIIKYEKPGSPPRE 2037
+S V+ + + P+ L + T +++ ++W+ P +R+TGY+++ K G+
Sbjct: 23319 ETSDAVLVSEVPL-VPAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGTERWM 23377
Query: 2038 VVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEP-----LIGRKKTDELP--QLVT 2090
V +P V E T+T L G +Y + A SEP + + LP L T
Sbjct: 23378 KVVTLKPTVLEHTVTSLNEGEQYLFRIRAQNEKGVSEPRETVTAVTVQDLRVLPTIDLST 23437
Query: 2091 LPHPNLHGP 2099
+P +H P
Sbjct: 23438 MPQKTIHVP 23446
Score = 123 bits (309), Expect = 2e-27
Identities = 310/1432 (21%), Positives = 508/1432 (35%), Gaps = 230/1432 (16%)
Query: 814 PPDPT-VDQVDDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTLS 868
PP P + V + W+ P +PI Y + + T ++ + +
Sbjct: 14170 PPGPVEISNVSAEKATLTWTPPLEDGGSPIKSYILEKRETSRLLWTVVSEDIQSCRHVAT 14229
Query: 869 DLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVE-VTDVKVTIMW 927
L G +Y + AV + PV Q E P P + V VT T+ W
Sbjct: 14230 KLIQGNEYIFRVSAVNHYGKGEPV--QSEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSW 14287
Query: 928 TPPE----SAVTGYRVDVIPV-NLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSH 982
P S +TGY V+ +L + P+S + +VTGL G TY F+V A +
Sbjct: 14288 KRPVDDGGSEITGYHVERREKKSLRWVRAIKTPVS-DLRCKVTGLQEGSTYEFRVSAENR 14346
Query: 983 GRESKPLTAQQTTKL-DA------PTNLQFVNETDSTVLVRWTPPR----AQITGYRLTV 1031
P A + + DA P+N + T + + W P +ITGY +
Sbjct: 14347 AGIGPPSEASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLAWGKPHYDGGLEITGYVVEH 14406
Query: 1032 GLTRRGQPRQYNVGPS--VSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGS 1089
+ G + ++++ + +LQ +Y + AI A +
Sbjct: 14407 QKVGDEAWIKDTTGTALRITQFVVPDLQTKEKYNFRISAINDAGVGEPAVIPDVEIVERE 14466
Query: 1090 SIPPY--NTEVTETTIVITWTPAPRIGFKLGVR-PSQGGEAPREVTSDSGSIVVSG---- 1142
P + + E+ T +V R G + + P +G AP EVT +I +
Sbjct: 14467 MAPDFELDAELRRTLVV-------RAGLSIRIFVPIKGRPAP-EVTWTKDNINLKNRANI 14518
Query: 1143 ---------LTPGVEYVYT---IQVLRDGQERDAPIVN-KVVTPLSPPTNLH-LEANPDT 1188
+ P T + + + + + VN +V+ P NL + D+
Sbjct: 14519 ENTESFTLLIIPECNRYDTGKFVMTIENPAGKKSGFVNVRVLDTPGPVLNLRPTDITKDS 14578
Query: 1189 GVLTVSWERSTTPD---ITGYRITTTPTNGQQGNSLEEVVHADQSSCTFD--NLSPGLEY 1243
+T+ W+ IT Y + + ++ H CT+ LS G EY
Sbjct: 14579 --VTLHWDLPLIDGGSRITNYIVEKREATRKSYSTATTKCH----KCTYKVTGLSEGCEY 14632
Query: 1244 NVSV-----YTVKDDKESV-PISDTIIPEVPQLTDLSFVDITDSSIGLRWTPLN---SST 1294
V Y + + E+ P+ + P P L+ +DIT S++ L W S
Sbjct: 14633 FFRVMAENEYGIGEPTETTEPVKASEAPSPPD--SLNIMDITKSTVSLAWPKPKHDGGSK 14690
Query: 1295 IIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLE-------PGIDYDISVITLINGGES 1347
I GY I G D TV GLE G +Y V+ + + G S
Sbjct: 14691 ITGYVIEAQRKGS---------DQWTHITTVKGLECVVRNLTEGEEYTFQVMAVNSAGRS 14741
Query: 1348 APT----TLTQQTAVPPPTDLR-------FTNIGPDT---MRVTWAPPPSIDLTNFLVRY 1393
AP + ++ + P DLR G + + V P P++
Sbjct: 14742 APRESRPVIVKEQTMLPELDLRGIYQKLVIAKAGDNIKVEIPVLGRPKPTVTW------- 14794
Query: 1394 SPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGL---- 1449
K + + + + + + +L E V S S Y PL R G
Sbjct: 14795 ---KKGDQILKQTQRVNFETTATSTILNINECVRSDSGPY------PLTARNIVGEVGDV 14845
Query: 1450 ---------DSPTG-IDFSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPRED 1495
PTG I F +++++ T W P I+ Y + S E
Sbjct: 14846 ITIQVHDIPGPPTGPIKFDEVSSDFVTFSWDPPENDGGVPISNYVVEMRQTD-STTWVEL 14904
Query: 1496 RVPHSRNSITLTNLTPGTEYVVSIVALN------GREESPLLIGQQSTVSDVPRDLEVVA 1549
R + T LT G EY + A N G + ++ V P +V A
Sbjct: 14905 ATTVIRTTYKATRLTTGLEYQFRVKAQNRYGVGPGITSACIVANYPFKVPGPPGTPQVTA 14964
Query: 1550 ATPTSLLISWDAP----AVTVRYYRITYGETGGN--SPVQEFTVPGSKSTATISGLKPGV 1603
T S+ ISW P + Y + E G V + VPG+ + SGL G+
Sbjct: 14965 VTKDSMTISWHEPLSDGGSPILGYHVERKERNGILWQTVSKALVPGNIFKS--SGLTDGI 15022
Query: 1604 DYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKW----LPSSSP 1659
Y V A G S S + ID P + ++ +++++KW
Sbjct: 15023 AYEFRVIAENMAGKSKPSKPSEPMLALDPIDPPGKPVPLNITRHTVTLKWAKPEYTGGFK 15082
Query: 1660 VTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQ-- 1717
+T Y V K + + E T+ GL Y V A+N +G P +
Sbjct: 15083 ITSYIVEKRDLPNGRWLKANFSNILENEFTVSGLTEDAAYEFRVIAKNAAGAISPPSEPS 15142
Query: 1718 TAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDT 1777
A+T D DV+ IK+ + + + + D P + +D
Sbjct: 15143 DAITCRD--------DVEAPKIKVDVKFKDTVILKAGEAFRLEADVSGRPPPTMEWSKDG 15194
Query: 1778 AELQGL---------------------RPGSEYTVSVVALHDDMESQPLIGTQSTAIPAP 1816
EL+G R YT++ A + ++ + + P P
Sbjct: 15195 KELEGTAKLEIKIADFSTNLVNKDSTRRDSGAYTLT--ATNPGGFAKHIFNVKVLDRPGP 15252
Query: 1817 TD--LKFTQVTPTSLSAQWTPP----NVQLTGYRVRVTPKEKTGPMKEINLAPD--SSSV 1868
+ L T+VT W PP ++ Y + K +T + N+A + + +
Sbjct: 15253 PEGPLAVTEVTSEKCVLSWFPPLDDGGAKIDHY---IVQKRETSRLAWTNVASEVQVTKL 15309
Query: 1869 VVSGLMVATKY-----EVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITI 1923
V+ L+ +Y V+ Y + + L S P V PP+ VT T+ ++ +
Sbjct: 15310 KVTKLLKGNEYIFRVMAVNKYGVGEPLESEPVL-AVNPYGPPDPPKNPEVTTITKDSMVV 15368
Query: 1924 SW----RTKTETITGFQVDAVPANGQTPIQRTIK--PDVRSYTITGLQPGTDYKIYLYTL 1977
W I + V+ GQ I+ K D+R Y ++GL G +Y+ +
Sbjct: 15369 CWGHPDSDGGSEIINYIVERRDKAGQRWIKCNKKTLTDLR-YKVSGLTEGHEYEFRIMAE 15427
Query: 1978 NDNARSSP-------VVIDASTAIDAPSNLRFLATTPNSLLVSWQPP----RARITGYII 2026
N S+P D P N R L T+ +S+ ++W P + ITGY++
Sbjct: 15428 NAAGISAPSPTSPFYKACDTVFKPGPPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMV 15487
Query: 2027 KYEKPGSPPREVVPRPRP-GVTEATITGLEPGTEYTIYVIALKNNQKSEPLI 2077
+ P ++V P T TITGL EY I + A+ + EP +
Sbjct: 15488 EIALPEEDEWQIVTPPAGLKATSYTITGLTENQEYKIRIYAMNSEGLGEPAL 15539
Score = 123 bits (309), Expect = 2e-27
Identities = 338/1634 (20%), Positives = 602/1634 (36%), Gaps = 228/1634 (13%)
Query: 613 EVFITETPSQPNSHP-----------IQWNAPQ---PSHISKYILRWRPKNSVGRWKEAT 658
E ++ P P P +QW P S I+ YI+ R GRW +A+
Sbjct: 17208 ECYVARDPCDPPGTPEPIMVKRNEITLQWTKPVYDGGSMITGYIVEKRDLPD-GRWMKAS 17266
Query: 659 IPGHLNS-YTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTP 717
+ + +T+ GL YE ++I+ G + S ST +T +
Sbjct: 17267 FTNVIETQFTVSGLTEDQRYEFRVIAKNAAGA-------ISKPSDST----GPITAKDEV 17315
Query: 718 FSPLVATSESVTEITASSFVVSWVSASD-------TVSGFRVEYELSEEGD-EPQYLDLP 769
P ++ + + ++ +D T+ R + E+ E E + D
Sbjct: 17316 ELPRISMDPKFRDTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFK 17375
Query: 770 STATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPT-VDQVDDTSIV 828
+ V + G +YI+ ++ G +S ++ P P P V V
Sbjct: 17376 ALLI-VKDAIRIDGGQYILRASNVA--GSKSFPVNVKVLDRPGPPEGPVQVTGVTSEKCS 17432
Query: 829 VRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITI---- 880
+ WS P + I+ Y + + + T + NS+ ++ L G +Y I
Sbjct: 17433 LTWSPPLQDGGSDISHYVVEKRETSRLAWTVVASEVVTNSLKVTKLLEGNEYVFRIMAVN 17492
Query: 881 -YAVEENQESTPVVIQQETTGTPRSDTVPSP-RDLQFVEVTDVKVTIMWTPPES----AV 934
Y V E ES PV+++ +P P + L+ + +T+ W P+S +
Sbjct: 17493 KYGVGEPLESAPVLMKNPFV-------LPGPPKSLEVTNIAKDSMTVCWNRPDSDGGSEI 17545
Query: 935 TGYRV---DVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTA 991
GY V D + + +R+ R VTGL+ Y F+V A + +P A
Sbjct: 17546 IGYIVEKRDRSGIRWIKCNKRRITDLR---LRVTGLTEDHEYEFRVSAENAAGVGEPSPA 17602
Query: 992 -------QQTTKLDAPTNLQFVNETDSTVLVRWTPP----RAQITGYRLTVGLTRRGQPR 1040
K PTN V+ T +++ + W P ++I GY V + + +
Sbjct: 17603 TVYYKACDPVFKPGPPTNAHIVDTTKNSITLAWGKPIYDGGSEILGY--VVEICKADEEE 17660
Query: 1041 QYNVGPS----VSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNT 1096
V P V+++ + L EY + + A+ +AT V T++P +
Sbjct: 17661 WQIVTPQTGLRVTRFEISKLTEHQEYKIRVCALN-KVGLGEATSVPGTVKPEDKLEAPEL 17719
Query: 1097 EVTETT---IVITWTPAPRIGFKLGVRPS-------QGGEAPREVTSDSG----SIVVSG 1142
++ IV+ + RI RP+ + GE +V + G + +
Sbjct: 17720 DLDSELRKGIVVRAGGSARIHIPFKGRPTPEITWSREEGEFTDKVQIEKGVNYTQLSIDN 17779
Query: 1143 LTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHL-EANPDTGVLTVSWERSTTP 1201
Y +++ + A + KV+ PP NL + E D+ L WE P
Sbjct: 17780 CDRNDAGKYILKLENSSGSKSAFVTVKVLDTPGPPQNLAVKEVRKDSAFLV--WE---PP 17834
Query: 1202 DITGYRITTTPTNGQQGNSLEEVVHAD----QSSCTFDNLSPGLEYNVSVYTVKDDKESV 1257
I G ++ ++ + + ++S +NL+ G Y V + V
Sbjct: 17835 IIDGGAKVKNYVIDKRESTRKAYANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFGVGV 17894
Query: 1258 PIS--DTIIPEVPQLTD--LSFVDITDSSIGLRWTPLN---SSTIIGYRITVVAAGEGIP 1310
P+ D + P ++ D++ +S L W S ++GY V +G
Sbjct: 17895 PVETVDAVKAAEPPSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLGY--VVEMQPKGTE 17952
Query: 1311 IFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTT---------LTQQTAVPPP 1361
+ +S V VTGL G +Y V G+S P LT Q ++ P
Sbjct: 17953 KWSIVAESKVCNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKLP 18012
Query: 1362 TDLRFTNIGPD---TMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTN 1418
+ G D + V P P+I +++ P+K +++ + + VL +
Sbjct: 18013 FNTYSIQAGEDLKIEIPVIGRPRPNI---SWVKDGEPLK---QTTRVNVEETATSTVL-H 18065
Query: 1419 LLPGTE------YVVSVSSVYEQHESTPLRGRQKTGLDSPTG-IDFSDITANSFTVHWIA 1471
+ G + V + +S E+ + +K G P G + F +++A+ + W
Sbjct: 18066 IKEGNKDDFGKYTVTATNSAGTATENLSVIVLEKPG--PPVGPVRFDEVSADFVVISWEP 18123
Query: 1472 PRAT----ITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREE 1527
P T I+ Y + + + +R +I +T L GTEY I A N +
Sbjct: 18124 PAYTGGCQISNYIVEKR-DTTTTTWHMVSATVARTTIKITKLKTGTEYQFRIFAENRYGK 18182
Query: 1528 SPLLIGQQSTVS------DVPRDLEVVAATPTSLLISWDAP----AVTVRYYRITYGETG 1577
S L + V P V + + +L+ W P + Y + E
Sbjct: 18183 SAPLDSKAVIVQYPFKEPGPPGTPFVTSISKDQMLVQWHEPVNDGGTKIIGYHLEQKEKN 18242
Query: 1578 GNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPS 1637
V+ P + +GL G++Y V A G S R D P
Sbjct: 18243 SILWVKLNKTPIQDTKFKTTGLDEGLEYEFKVSAENIVGIGKPSKVSECFVARDPCDPPG 18302
Query: 1638 QMQVTDVQDNSISVKW----LPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGL 1693
+ + + N++++KW S +TGY V K +TE T+ GL
Sbjct: 18303 RPEAIVITRNNVTLKWKKPAYDGGSKITGYIVEKKDLPDGRWMKASFTNVLETEFTVSGL 18362
Query: 1694 QPTVEYVVSVYAQNPSGE-SQPLVQT-AVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVS 1751
Y V A+N +G S+P + A+T D ++D + + + V
Sbjct: 18363 VEDQRYEFRVIARNAAGNFSEPSDSSGAITARD--------EIDAPNASLDPKYKDVIVV 18414
Query: 1752 RYRVTYSSPED----GIHELFPAPDGE--EDTAELQGLRPGSEYTVSVV--ALHDD---- 1799
T+ D I ++ + DG+ E+TA ++ + T VV + D
Sbjct: 18415 HAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQY 18474
Query: 1800 -MESQPLIGTQSTAI-------PAPTD--LKFTQVTPTSLSAQWTPPNVQLTGYRVR--V 1847
++ + GT+S I P P + LK T VT W PP +Q G + +
Sbjct: 18475 ILKLSNVGGTKSIPITVKVLDRPGPPEGPLKVTGVTAEKCYLAWNPP-LQDGGANISHYI 18533
Query: 1848 TPKEKTGPMK--EINLAPDSSSVVVSGLMVATKY-----EVSVYALKDTLTSRPAQGVVT 1900
K +T + +++ + + V+ L+ +Y V+ Y + + L S P
Sbjct: 18534 IEKRETSRLSWTQVSTEVQALNYKVTKLLPGNEYIFRVMAVNKYGIGEPLESGPVT-ACN 18592
Query: 1901 TLENVSPPRRARVTDATETTITISWRTKTE----TITGFQVDAVPANG--QTPIQRTIKP 1954
+ PP V+ T+ ++ ++W + I G+ ++ G T +
Sbjct: 18593 PYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDKEGVRWTKCNKKTLT 18652
Query: 1955 DVRSYTITGLQPGTDYKIYLYTLNDNARSSPV-------VIDASTAIDAPSNLRFLATTP 2007
D+R +TGL G Y+ + N P DA PSN + T+
Sbjct: 18653 DLR-LRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRACDALYPPGPPSNPKVTDTSR 18711
Query: 2008 NSLLVSWQPP----RARITGYIIKYEKPGSPPREVVPRPRPGV--TEATITGLEPGTEYT 2061
+S+ ++W P A + GY+++ K + P G+ + T+T L+ TEY
Sbjct: 18712 SSVSLAWSKPIYDGGAPVKGYVVEV-KEAAADEWTTCTPPTGLQGKQFTVTKLKENTEYN 18770
Query: 2062 IYVIALKNNQKSEP 2075
+ A+ + EP
Sbjct: 18771 FRICAINSEGVGEP 18784
Score = 123 bits (309), Expect = 2e-27
Identities = 314/1502 (20%), Positives = 546/1502 (36%), Gaps = 190/1502 (12%)
Query: 619 TPSQPNSHPIQWNAP---QPSHISKYILRWRPKNSVGRWKEATIPGHLNS--YTIKGLKP 673
T + +S + W+ P + + Y++ + + + W T P L +T+ LK
Sbjct: 18707 TDTSRSSVSLAWSKPIYDGGAPVKGYVVEVK-EAAADEWTTCTPPTGLQGKQFTVTKLKE 18765
Query: 674 GVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITA 733
Y ++ +I G E T + V + P L A V + A
Sbjct: 18766 NTEYNFRICAINSEGVGE------PATLPGSVVAQERIE---PPEIELDADLRKVVVLRA 18816
Query: 734 SSFVVSWVSASDTVSGFRVEYELSEEGDEP-----QYLDLPSTATSVNIPDLLPGRKYIV 788
S+ + +V T+ G R E E+ E E +++ S+ T + I ++
Sbjct: 18817 SATLRLFV----TIKG-RPEPEVKWEKAEGILTDRAQIEVTSSFTMLVIDNVTRFDSGRY 18871
Query: 789 NVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ----APITGYRIV 844
N+ + G ++ ++ +P AP + T+ +V S+ + W P A IT Y +
Sbjct: 18872 NLTLENNSGSKTAFVNVRVLDSPSAPVNLTIREVKKDSVTLSWEPPLIDGGAKITNYIVE 18931
Query: 845 YSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRS 904
+ + + T + + +LQ G Y + A E P ETT +
Sbjct: 18932 KRETTRKAYATITNNCTKTTFRIENLQEGCSYYFRVLASNEYGIGLPA----ETTEPVKV 18987
Query: 905 DTVPSPRD-LQFVEVTDVKVTIMWTPPES----AVTGYRVDVIPVNLPGEHGQRLPISRN 959
P P + V+VT TI W PES +TGY V++ E +
Sbjct: 18988 SEPPLPPGRVTLVDVTRNTATIKWEKPESDGGSKITGYVVEMQTKG--SEKWSTCTQVKT 19045
Query: 960 TFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWT- 1018
A ++GL+ G Y F+V AV+ S P +L P + + S L T
Sbjct: 19046 LEATISGLTAGEEYVFRVAAVNEKGRSDP------RQLGVPVIARDIEIKPSVELPFHTF 19099
Query: 1019 --PPRAQIT-------GYRLTVGLTRRGQP----RQYNVGPSVSKYPLRNLQPASEYTVS 1065
R Q+ + TV + GQ + NV S + L +++ AS+ V
Sbjct: 19100 NVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSL-SIKEASKEDVG 19158
Query: 1066 LVAIKGNQESPKATGVFTTL---QPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPS 1122
+ + + T T + +PG P EV+ +I I+W P G G + S
Sbjct: 19159 TYELCVSNSAGSITVPITIIVLDRPGPPGPIRIDEVSCDSITISWNPPEYDG---GCQIS 19215
Query: 1123 QGGEAPREVTSDSGSIV----------VSGLTPGVEYVYTIQVL-RDGQ----ERDAPIV 1167
+E TS + IV + LT G EY + + R G+ E A +
Sbjct: 19216 NYIVEKKETTSTTWHIVSQAVARTSIKIVRLTTGSEYQFRVCAENRYGKSSYSESSAVVA 19275
Query: 1168 NKVVTPLSPP-TNLHLEANPDTGVLTVSWERSTTPD---ITGYRITTTPTNGQQGNSLEE 1223
+P PP T + A T + V+W+ + GY + + + +
Sbjct: 19276 EYPFSPPGPPGTPKVVHATKST--MLVTWQVPVNDGGSRVIGYHLEYKERSSILWSKANK 19333
Query: 1224 VVHADQSSCTFDNLSPGLEYNVSVYT--------VKDDKESVPISDTIIPE-VPQLTDLS 1274
++ AD + L GL Y VY E VP D P P++T+
Sbjct: 19334 ILIAD-TQMKVSGLDEGLMYEYRVYAENIAGIGKCSKSCEPVPARDPCDPPGQPEVTN-- 19390
Query: 1275 FVDITDSSIGLRWTPLN---SSTIIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPG 1331
IT S+ L+W+ + + I GY + +G + ++ + Y+ VT L
Sbjct: 19391 ---ITRKSVSLKWSKPHYDGGAKITGYIVERRELPDGRWLKCNYTNIQETYFEVTELTED 19447
Query: 1332 IDYDISVI------TLINGGESAPTTLTQQTAVPPPT--DLRFTNI----GPDTMRVT-- 1377
Y+ V ++ ES + + PP D++F ++ + +++
Sbjct: 19448 QRYEFRVFARNAADSVSEPSESTGPIIVKDDVEPPRVMMDVKFRDVIVVKAGEVLKINAD 19507
Query: 1378 --WAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNL----LPGTEYVVSVSS 1431
P P I + E+ A I +DN +LT +YV+++ +
Sbjct: 19508 IAGRPLPVISWAKDGIEI------EERARTEIISTDNHTLLTVKDCIRRDTGQYVLTLKN 19561
Query: 1432 VYEQHE-STPLRGRQKTGLDSPTG-IDFSDITANSFTVHWIAPR----ATITGYRI-RHH 1484
V + + K G P G ++ + +TA ++ W P+ A I Y + +
Sbjct: 19562 VAGTRSVAVNCKVLDKPG--PPAGPLEINGLTAEKCSLSWGRPQEDGGADIDYYIVEKRE 19619
Query: 1485 PEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGR------EESPLLIGQQSTV 1538
H + E + S +T L G EY+ + +N E + TV
Sbjct: 19620 TSHLAWTICEGEL--QMTSCKVTKLLKGNEYIFRVTGVNKYGVGEPLESVAIKALDPFTV 19677
Query: 1539 SDVPRDLEVVAATPTSLLISWDAP----AVTVRYYRITYGETGGNSPVQEFTVPGSKSTA 1594
P LE+ + T S+ + W P + Y I E V+ P
Sbjct: 19678 PSPPTSLEITSVTKESMTLCWSRPESDGGSEISGYIIERREKNSLRWVRVNKKPVYDLRV 19737
Query: 1595 TISGLKPGVDYTITVYAVTGRGDS-PASSKPISINYRTEI---DKPSQMQVTDVQDNSIS 1650
+GL+ G +Y VYA G S P+ + P+ I + PS+ ++ D +I+
Sbjct: 19738 KSTGLREGCEYEYRVYAENAAGLSLPSETSPL-IRAEDPVFLPSPPSKPKIVDSGKTTIT 19796
Query: 1651 VKWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQ 1706
+ W+ +P+TGY V K+ KT TE TI GL EYV V +
Sbjct: 19797 IAWVKPLFDGGAPITGYTVEYK-KSDDTDWKTSIQSLRGTEYTISGLTTGAEYVFRVKSV 19855
Query: 1707 NPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRY---------RVTY 1757
N G S P + + D+D + K + V +
Sbjct: 19856 NKVGASDPSDSSDPQIAKEREEEPLFDIDSEMRKTLIVKAGASFTMTVPFRGRPVPNVLW 19915
Query: 1758 SSPEDGIHELFPAPDGEEDTA---ELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIP 1814
S P+ + + T+ E +YT+++ + ++ T P
Sbjct: 19916 SKPDTDLRTRAYVDTTDSRTSLTIENANRNDSGKYTLTIQNVLSAASLTLVVKVLDTPGP 19975
Query: 1815 APTDLKFTQVTPTSLSAQWTPP----NVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVV 1870
PT++ VT S W P + Y + K + N + S V
Sbjct: 19976 -PTNITVQDVTKESAVLSWDVPENDGGAPVKNYHIEKREASKKAWVSVTNNC-NRLSYKV 20033
Query: 1871 SGLMVATKYEVSVYALKDTLTSRPA---QGVVTTLENVSPPRRARVTDATETTITISW-- 1925
+ L Y V + PA +GV T E SPP + VT ++ +++++W
Sbjct: 20034 TNLQEGAIYYFRVSGENEFGVGIPAETKEGVKIT-EKPSPPEKLGVTSISKDSVSLTWLK 20092
Query: 1926 --RTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARS 1983
I + V+A+ + ++ + + ++GL+ ++Y ++ N S
Sbjct: 20093 PEHDGGSRIVHYVVEALEKGQKNWVKCAVAKSTH-HVVSGLRENSEYFFRVFAENQAGLS 20151
Query: 1984 SP 1985
P
Sbjct: 20152 DP 20153
Score = 120 bits (301), Expect = 2e-26
Identities = 286/1368 (20%), Positives = 511/1368 (37%), Gaps = 206/1368 (15%)
Query: 866 TLSDLQPGVQYNITIYAVEENQEST-PVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVT 924
T++ L G +Y + A EN+ T P + + D P + +V+ ++T
Sbjct: 12051 TVTRLIEGNEYIFRVRA--ENKIGTGPPTESKPVIAKTKYDKPGRPDPPEVTKVSKEEMT 12108
Query: 925 IMWTPPE----SAVTGYRVDVIPVNLPGEHGQR-LPISRNTFAE----VTGLSPGVTYYF 975
++W PPE ++TGY ++ +H R +P++++ E V L P Y F
Sbjct: 12109 VVWNPPEYDGGKSITGYFLEK-----KEKHSTRWVPVNKSAIPERRMKVQNLLPDHEYQF 12163
Query: 976 KVFAVSH------GRESKPLTAQQTTKLDAP-TNLQFVNETDSTVLVRWTPP----RAQI 1024
+V A + S+P+ A+ + P TN + V+ T ++ + W P A I
Sbjct: 12164 RVKAENEIGIGEPSLPSRPVVAKDPIEPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAPI 12223
Query: 1025 TGY------RLTVGLTRRGQPRQYNVGPSVSK-YPLRNLQPASEYTVSL-----VAIKGN 1072
GY ++ G R V K + + +L EY + V I
Sbjct: 12224 IGYVVEMRPKIADASPDEGWKRCNAAAQLVRKEFTVTSLDENQEYEFRVCAQNQVGIGRP 12283
Query: 1073 QESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWT-------------PAPRIGFKLGV 1119
E +A L+P P + + + +VI PAP++ ++
Sbjct: 12284 AELKEAIKPKEILEP----PEIDLDASMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVG 12339
Query: 1120 RPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTN 1179
+ + ++ +V+ T Y++ ++ E+ + +V+ P ++
Sbjct: 12340 IDNVVRKGQVDLVDTMAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFVNVRVLDTPGPVSD 12399
Query: 1180 LHLEANPDTGVLTVSW---ERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDN 1236
L + T VSW E +T Y + + + +++ V ++S N
Sbjct: 12400 LKVSDVTKTSC-HVSWAPPENDGGSQVTHYIVEKREADRKTWSTVTPEVK--KTSFHVTN 12456
Query: 1237 LSPGLEYNVSVYTVKDDKESVPI--------SDTII-PEVPQLTDLSFVDITDSSIGLRW 1287
L PG EY V V + VP SD + P+ P+ L ++T +S L W
Sbjct: 12457 LVPGNEYYFRVTAVNEYGPGVPTDVPKPVLASDPLSEPDPPR--KLEVTEMTKNSATLAW 12514
Query: 1288 TPL---NSSTIIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLING 1344
P + I GY + + + ++ VTGL+ G Y V
Sbjct: 12515 LPPLRDGGAKIDGYITSYREEEQPADRWTEYSVVKDLSLVVTGLKEGKKYKFRVAARNAV 12574
Query: 1345 GESAPTTL-----TQQTAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVK-- 1397
G S P ++ +PP + P+ + + I+ + + K
Sbjct: 12575 GVSLPREAEGVYEAKEQLLPPKI------LMPEQITIKAGKKLRIEAHVYGKPHPTCKWK 12628
Query: 1398 -NEEDV---AELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSP- 1452
E++V + L++ +D++ +L + S E T + + +D+P
Sbjct: 12629 KGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPG 12688
Query: 1453 ---TGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPH----SRNSIT 1505
D SDI A++ ++ W P G I ++ R D V ++ S
Sbjct: 12689 PPQPPFDISDIDADACSLSWHIPLED-GGSNITNYIVEKCDVSRGDWVTALASVTKTSCR 12747
Query: 1506 LTNLTPGTEYVVSIVALN--GREE---SPLLIGQ-QSTVSDVPRDLEVVAATPTSLLISW 1559
+ L PG EY+ + A N G E SP ++ Q V P++ V + ++W
Sbjct: 12748 VGKLIPGQEYIFRVRAENRFGISEPLTSPKMVAQFPFGVPSEPKNARVTKVNKDCIFVAW 12807
Query: 1560 DAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATI----------------SGLKPGV 1603
D P ++ G SP+ + + + + + +GL G+
Sbjct: 12808 DRP------------DSDGGSPIIGYLIERKERNSLLWVKANDTLVRSTEYPCAGLVEGL 12855
Query: 1604 DYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWL----PSSSP 1659
+Y+ +YA+ G SP S + R +D P + +V DV +++S+ W S
Sbjct: 12856 EYSFRIYALNKAGSSPPSKPTEYVTARMPVDPPGKPEVIDVTKSTVSLIWARPKHDGGSK 12915
Query: 1660 VTGYRVTTTPKNGPGPTKTKTAGPD--QTEMTIEGLQPTVEYVVSVYAQN------PSGE 1711
+ GY V G + TA Q E T GL+ +Y A+ PS
Sbjct: 12916 IIGYFVEACKLPGDKWVRCNTAPHQIPQEEYTATGLEEKAQYQFRAIARTAVNISPPSEP 12975
Query: 1712 SQP---LVQTAVTNIDRPKGL-------AFTDVDVDSIKIAWESPQGQVS-RYRVTYSSP 1760
S P L + ID + A T+V +D+ + P VS + T P
Sbjct: 12976 SDPVTILAENVPPRIDLSVAMKSLLTVKAGTNVCLDA--TVFGKPMPTVSWKKDGTLLKP 13033
Query: 1761 EDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPA-PTDL 1819
+GI A T EL + ++ A + I + P P +
Sbjct: 13034 AEGIK---MAMQRNLCTLELFSVNRKDSGDYTITAENSSGSKSATIKLKVLDKPGPPASV 13090
Query: 1820 KFTQVTPTSLSAQWTPP----NVQLTGYRVRVTPKEKTGP-MKEINLAPDSSSVVVSGLM 1874
K ++ W PP ++T Y V +E + P +++ +S V L+
Sbjct: 13091 KINKMYSDRAMLSWEPPLEDGGSEITNY--IVDKRETSRPNWAQVSATVPITSCSVEKLI 13148
Query: 1875 VATKYEVSV-----YALKDTLTSRPAQGVVTTLENVSPPRRAR---VTDATETTITISWR 1926
+Y+ + Y + D + + PA PP R +++ T+ +T+SW+
Sbjct: 13149 EGHEYQFRICAENKYGVGDPVFTEPA----IAKNPYDPPGRCDPPVISNITKDHMTVSWK 13204
Query: 1927 TKTE----TITGFQVDAVPANGQTPIQRTIKPDV-RSYTITGLQPGTDYKIYLYTLNDNA 1981
+ ITG+ ++ + KP + R+ TGLQ GT+Y+ + +N
Sbjct: 13205 PPADDGGSPITGYLLEKRETQAVNWTKVNRKPIIERTLKATGLQEGTEYEFRVTAINKAG 13264
Query: 1982 RSSPVVIDASTAIDA---------PSNLRFLATTPNSLLVSWQPPR----ARITGYIIKY 2028
P DAS A A P+ + TT +S+ +SW P + I GY+++
Sbjct: 13265 PGKP--SDASKAAYARDPQYPPGPPAFPKVYDTTRSSVSLSWGKPAYDGGSPIIGYLVEV 13322
Query: 2029 EKPGSPPREVVPRPRP-GVTEATITGLEPGTEYTIYVIALKNNQKSEP 2075
++ S P+ T +TGL T+Y V A+ S+P
Sbjct: 13323 KRADSDNWVRCNLPQNLQKTRFEVTGLMEDTQYQFRVYAVNKIGYSDP 13370
Score = 120 bits (301), Expect = 2e-26
Identities = 304/1512 (20%), Positives = 534/1512 (35%), Gaps = 204/1512 (13%)
Query: 718 FSPLVATSESVTEITASSFVVSW----VSASDTVSGFRVEYELSEEGDEPQYLDLPSTA- 772
F P T+ + + T +S ++W + G+ VE + + +E + P T
Sbjct: 17613 FKPGPPTNAHIVDTTKNSITLAWGKPIYDGGSEILGYVVE--ICKADEEEWQIVTPQTGL 17670
Query: 773 --TSVNIPDLLPGRKYIVNVYQISEDG--EQSLILSTSQTTAPDAPPDPTVDQVDDTSIV 828
T I L ++Y + V +++ G E + + T + P+ +D IV
Sbjct: 17671 RVTRFEISKLTEHQEYKIRVCALNKVGLGEATSVPGTVKPEDKLEAPELDLDSELRKGIV 17730
Query: 829 VRW---SRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYN-ITIYAVE 884
VR +R P G +P + S E + ++ GV Y ++I +
Sbjct: 17731 VRAGGSARIHIPFKGRP---TPEITWSREEGEFTDKVQ------IEKGVNYTQLSIDNCD 17781
Query: 885 ENQESTPVVIQQETTGTPRS-------DTVPSPRDLQFVEVTDVKVTIMWTPP----ESA 933
N ++ + ++G+ + DT P++L EV ++W PP +
Sbjct: 17782 RNDAGKYILKLENSSGSKSAFVTVKVLDTPGPPQNLAVKEVRKDSAFLVWEPPIIDGGAK 17841
Query: 934 VTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQ 993
V Y +D S+ +F +V L+ G YYF+V A + P+
Sbjct: 17842 VKNYVIDKRESTRKAYANVSSKCSKTSF-KVENLTEGAIYYFRVMAENEFGVGVPVETVD 17900
Query: 994 TTKLDAPTN------LQFVNETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYN 1043
K P + L V++T ++++ W P +++ GY V + +G +
Sbjct: 17901 AVKAAEPPSPPGKVTLTDVSQTSASLM--WEKPEHDGGSRVLGY--VVEMQPKGTEKWSI 17956
Query: 1044 VGPS-VSKYPLRNLQPASEYTVSLVAIKGNQES-PKATGVFT-----TLQPGSSIPPYNT 1096
V S V + L EY + A +S P+ GV T+QP +P +NT
Sbjct: 17957 VAESKVCNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKLP-FNT 18015
Query: 1097 ------EVTETTIVITWTPAPRIGF-KLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEY 1149
E + I + P P I + K G Q E T+ S + +
Sbjct: 18016 YSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFG 18075
Query: 1150 VYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTP---DITGY 1206
YT+ + V+ PP + +SWE I+ Y
Sbjct: 18076 KYTVTATNSAGTATENLSVIVLEKPGPPVGPVRFDEVSADFVVISWEPPAYTGGCQISNY 18135
Query: 1207 RITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTII-- 1264
+ T + + V +++ L G EY ++ +S P+ +
Sbjct: 18136 IVEKRDTTTTTWHMVSATVA--RTTIKITKLKTGTEYQFRIFAENRYGKSAPLDSKAVIV 18193
Query: 1265 ---------PEVPQLTDLSFVDITDSSIGLRW-TPLNS--STIIGYRITVVAAGEGIPIF 1312
P P +T +S + ++W P+N + IIGY + + +
Sbjct: 18194 QYPFKEPGPPGTPFVTSIS-----KDQMLVQWHEPVNDGGTKIIGYHLEQKEKNSILWVK 18248
Query: 1313 EDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQ----QTAVPPPTDLRFTN 1368
+ + TGL+ G++Y+ V G P+ +++ + PP
Sbjct: 18249 LNKTPIQDTKFKTTGLDEGLEYEFKVSAENIVGIGKPSKVSECFVARDPCDPPGRPEAIV 18308
Query: 1369 IGPDTMRVTWAPPP---SIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEY 1425
I + + + W P +T ++V K+ D + S TN+L TE+
Sbjct: 18309 ITRNNVTLKWKKPAYDGGSKITGYIVEK---KDLPDGRWMKAS-------FTNVLE-TEF 18357
Query: 1426 VVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITG-YR---I 1481
VS V +Q + R G S ITA AP A++ Y+ +
Sbjct: 18358 TVS-GLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARD---EIDAPNASLDPKYKDVIV 18413
Query: 1482 RHHPEHF------SGRPREDRV--------------PHSRNSITLTNL-------TPGTE 1514
H E F G+P D V +++I T L T G +
Sbjct: 18414 VHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQ 18473
Query: 1515 YVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAP----AVTVRYYR 1570
Y++ + + G + P+ + L+V T ++W+ P + +Y
Sbjct: 18474 YILKLSNVGGTKSIPITVKVLDRPGPPEGPLKVTGVTAEKCYLAWNPPLQDGGANISHYI 18533
Query: 1571 ITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRG-DSPASSKPISI-N 1628
I ET S Q T + + ++ L PG +Y V AV G P S P++ N
Sbjct: 18534 IEKRETSRLSWTQVSTEVQALNYK-VTKLLPGNEYIFRVMAVNKYGIGEPLESGPVTACN 18592
Query: 1629 YRTEIDKPSQMQVTDVQDNSISVKWL----PSSSPVTGYRVTTTPKNGPGPTKTKTAGPD 1684
PS +V+ + +S+ V W + + GY + K G TK
Sbjct: 18593 PYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDKEGVRWTKCNKKTLT 18652
Query: 1685 QTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQT-------AVTNIDRPKGLAFTDVDVD 1737
+ + GL Y V A+N +G +P + A+ P TD
Sbjct: 18653 DLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRACDALYPPGPPSNPKVTDTSRS 18712
Query: 1738 SIKIAWESP----QGQVSRYRVTYSSPEDGIHELFPAPDGEEDTA-ELQGLRPGSEYTVS 1792
S+ +AW P V Y V P G + + L+ +EY
Sbjct: 18713 SVSLAWSKPIYDGGAPVKGYVVEVKEAAADEWTTCTPPTGLQGKQFTVTKLKENTEYNFR 18772
Query: 1793 VVALHDDMESQPL-----IGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRV 1847
+ A++ + +P + Q P +L L A T R+ V
Sbjct: 18773 ICAINSEGVGEPATLPGSVVAQERIEPPEIELDADLRKVVVLRASAT--------LRLFV 18824
Query: 1848 TPKEKTGPM----KEINLAPDSSSVVVSGLMV------ATKYEVSVY--ALKDTLTSRPA 1895
T K + P K + D + + V+ T+++ Y L++ S+ A
Sbjct: 18825 TIKGRPEPEVKWEKAEGILTDRAQIEVTSSFTMLVIDNVTRFDSGRYNLTLENNSGSKTA 18884
Query: 1896 QGVVTTLENVSPPRRARVTDATETTITISWRTKT----ETITGFQVDAVPANGQTPIQRT 1951
V L++ S P + + + ++T+SW IT + V+ + T
Sbjct: 18885 FVNVRVLDSPSAPVNLTIREVKKDSVTLSWEPPLIDGGAKITNYIVEKRETTRKAYATIT 18944
Query: 1952 IKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAP----SNLRFLATTP 2007
++ I LQ G Y + N+ P + P + + T
Sbjct: 18945 NNCTKTTFRIENLQEGCSYYFRVLASNEYGIGLPAETTEPVKVSEPPLPPGRVTLVDVTR 19004
Query: 2008 NSLLVSWQPPRA----RITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIY 2063
N+ + W+ P + +ITGY+++ + GS + + EATI+GL G EY
Sbjct: 19005 NTATIKWEKPESDGGSKITGYVVEMQTKGSEKWSTCTQVK--TLEATISGLTAGEEYVFR 19062
Query: 2064 VIALKNNQKSEP 2075
V A+ +S+P
Sbjct: 19063 VAAVNEKGRSDP 19074
Score = 119 bits (298), Expect = 4e-26
Identities = 329/1550 (21%), Positives = 553/1550 (35%), Gaps = 222/1550 (14%)
Query: 601 PLQTYPSSSGPVEVFITETPSQPN-------SHPIQWNAPQ---PSHISKYILRWRPKNS 650
P +T P VF+ PS+P + I W P + I+ Y + ++ +
Sbjct: 19763 PSETSPLIRAEDPVFLPSPPSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEYKKSDD 19822
Query: 651 VGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNT 710
WK + YTI GL G Y ++ S+ + G + + +S P +
Sbjct: 19823 TD-WKTSIQSLRGTEYTISGLTTGAEYVFRVKSVNKVGASD-------PSDSSDPQIAKE 19874
Query: 711 VTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVS--GFRVEYELSEEGDEP----Q 764
E PL +E+ + V + S + TV G V L + D
Sbjct: 19875 REEE-----PLFDID---SEMRKTLIVKAGASFTMTVPFRGRPVPNVLWSKPDTDLRTRA 19926
Query: 765 YLDLPSTATSVNIPDLL--PGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQV 822
Y+D + TS+ I + KY + + + +L++ T P P + TV V
Sbjct: 19927 YVDTTDSRTSLTIENANRNDSGKYTLTIQNVLSAASLTLVVKVLDTPGP--PTNITVQDV 19984
Query: 823 DDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNI 878
S V+ W P+ AP+ Y I + + + + S +++LQ G Y
Sbjct: 19985 TKESAVLSWDVPENDGGAPVKNYHIEKREASKKAWVSVTNNCNRLSYKVTNLQEGAIYYF 20044
Query: 879 TIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAV 934
+ E P ++ G ++ P L ++ V++ W PE S +
Sbjct: 20045 RVSGENEFGVGIPAETKE---GVKITEKPSPPEKLGVTSISKDSVSLTWLKPEHDGGSRI 20101
Query: 935 TGYRVDVIPVNLPGEHGQR----LPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKP-- 988
Y V+ + E GQ+ ++++T V+GL Y+F+VFA + S P
Sbjct: 20102 VHYVVEAL------EKGQKNWVKCAVAKSTHHVVSGLRENSEYFFRVFAENQAGLSDPRE 20155
Query: 989 -LTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPS 1047
L + P + N TV VR G L V + G+P V S
Sbjct: 20156 LLLPVLIKEQLEPPEIDMKNFPSHTVYVR--------AGSNLKVDIPISGKPLP-KVTLS 20206
Query: 1048 VSKYPLR-NLQPASEYTV---------SLVAIKGNQESPKATGVFTTL---------QPG 1088
PL+ ++ +E T S+ A G E A TT +PG
Sbjct: 20207 RDGVPLKATMRFNTEITAENLTINLKESVTADAGRYEITAANSSGTTKAFINIVVLDRPG 20266
Query: 1089 SSI-PPYNTEVTETTIVITWTPAPRIG-------FKLGVRPSQGGEAPREVTSDSGSIVV 1140
P +++TE ++ + W P G L S T + V
Sbjct: 20267 PPTGPVVISDITEESVTLKWEPPKYDGGSQVTNYILLKRETSTAVWTEVSATVARTMMKV 20326
Query: 1141 SGLTPGVEYVYTIQV-----LRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSW 1195
LT G EY + I+ + D + V T PP+ + N +TV W
Sbjct: 20327 MKLTTGEEYQFRIKAENRFGISDHIDSACVTVKLPYTTPGPPSTPWV-TNVTRESITVGW 20385
Query: 1196 ERSTT---PDITGYRITTTPTNG---QQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYT 1249
+ + GY + N Q+ N L V+ T +S GL Y VY
Sbjct: 20386 HEPVSNGGSAVVGYHLEMKDRNSILWQKANKL--VIRTTHFKVT--TISAGLIYEFRVYA 20441
Query: 1250 V------KDDKESVPISDTIIPEVPQLTDLSFVDITDSSIGLRWTPL---NSSTIIGYRI 1300
K S P+ E P+ ++ DI+ +S+ L W S I GY +
Sbjct: 20442 ENAAGVGKPSHPSEPVLAIDACEPPR--NVRITDISKNSVSLSWQQPAFDGGSKITGYIV 20499
Query: 1301 TVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISV------------------ITLI 1342
+G F + + + ++GL Y+ V IT I
Sbjct: 20500 ERRDLPDGRWTKASFTNVTETQFIISGLTQNSQYEFRVFARNAVGSISNPSEVVGPITCI 20559
Query: 1343 N--GGE--SAPTTLTQQTAVPPPTD--LRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPV 1396
+ GG P T+ T LR G + W TN LV V
Sbjct: 20560 DSYGGPVIDLPLEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALV---CV 20616
Query: 1397 KNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTG-I 1455
+N D+A + I +D L Y + + + +T +R + P G I
Sbjct: 20617 ENTTDLASILIKDADR-------LNSGCYELKLRNAMGSASAT-IRVQILDKPGPPGGPI 20668
Query: 1456 DFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNS-------ITLTN 1508
+F +TA T+ W P A G +I H + + RV S S IT T
Sbjct: 20669 EFKTVTAEKITLLW-RPPADDGGAKITH---YIVEKRETSRVVWSMVSEHLEECIITTTK 20724
Query: 1509 LTPGTEYVVSIVALNGRE-----ESPLLIGQQSTVSDVPRDL-EVVAATPTSLLISWDAP 1562
+ G EY+ + A+N ES ++ + + V+ P + EV T S+ + W P
Sbjct: 20725 IIKGNEYIFRVRAVNKYGIGEPLESDSVVAKNAFVTPGPPGIPEVTKITKNSMTVVWSRP 20784
Query: 1563 A------VTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRG 1616
++ + ++ G V + T+ ++ T GL DY V AV G
Sbjct: 20785 IADGGSDISGYFLEKRDKKSLGWFKVLKETIRDTRQKVT--GLTENSDYQYRVCAVNAAG 20842
Query: 1617 DSPASSKPISINYRTEID---KPSQMQVTDVQDNSISVKW----LPSSSPVTGYRVTTTP 1669
P S ID P+++++ D +SI++ W S VTGY V
Sbjct: 20843 QGPFSEPSEFYKAADPIDPPGPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVVEIRQ 20902
Query: 1670 KNGPGPTKTKTAGPDQ-TEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKG 1728
T T G + TE + L+P V Y V A N +G+ +P+ +
Sbjct: 20903 GEEEEWTTVSTKGEVRTTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMN--EPVQAKDI 20960
Query: 1729 LAFTDVDVD-SIKIAWESPQGQVSRYRVTYSS--PEDGIHELFPAPDGEEDTAELQGLRP 1785
L ++D+D +++ + + G+ + + + P G + ++
Sbjct: 20961 LEAPEIDLDVALRTSVIAKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYSIENTDS 21020
Query: 1786 GSEYTVSVVALHDDME---------SQPLIGTQSTAI----PAPTDLKFTQVTPTSLSAQ 1832
S T+ V +D + +P T S + A L+ V+ +++
Sbjct: 21021 SSLLTIPQVTRNDTGKYILTIENGVGEPKSSTVSVKVLDTPAACQKLQVKHVSRGTVTLL 21080
Query: 1833 WTPPNVQLTGYRVRVTPKEKTGPMKEINLAP---DSSSVVVSGLMVATKYEVSVYALKDT 1889
W PP + + +++ + ++ S+S + L T + V A +
Sbjct: 21081 WDPPLIDGGSPIINYVIEKRDATKRTWSVVSHKCSSTSFKLIDLSEKTPFFFRVLAENEI 21140
Query: 1890 LTSRPAQGV--VTTLENVSPPRRARVTDATETTITISWRTKTE-----TITGFQVDAVPA 1942
P + V E +P R + D+T+T++ +SW TK + IT + V+
Sbjct: 21141 GIGEPCETTEPVKAAEVPAPIRDLSMKDSTKTSVILSW-TKPDFDGGSVITEYVVERKGK 21199
Query: 1943 NGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDAST 1992
QT I ++ L+ + + ++ N+ S PV I T
Sbjct: 21200 GEQTWSHAGISKTC-EIEVSQLKEQSVLEFRVFAKNEKGLSDPVTIGPIT 21248
Score = 118 bits (296), Expect = 6e-26
Identities = 330/1625 (20%), Positives = 588/1625 (36%), Gaps = 230/1625 (14%)
Query: 611 PVEVFITETPSQPNSHPIQWNAP---QPSHISKYILRWRPKNSVGRWKEATIPGHLNSYT 667
PV V + E +S + W P S I Y+++ R W T S+
Sbjct: 13485 PVNVTVKEISK--DSAYVTWEPPIIDGGSPIINYVVQKRDAERKS-WSTVTTECSKTSFR 13541
Query: 668 IKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSES 727
+ L+ G Y ++ + +YG + T + V TP P+V
Sbjct: 13542 VANLEEGKSYFFRVFAENEYGIGDPGE------------TRDAVKASQTP-GPVVDLK-- 13586
Query: 728 VTEITASSFVVSWVS----ASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPG 783
V ++ SS + W + G+ V++ L+EE + + S + + DL G
Sbjct: 13587 VRSVSKSSCSIGWKKPHSDGGSRIIGYVVDF-LTEENKWQRVMK--SLSLQYSAKDLTEG 13643
Query: 784 RKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWS---RPQAPITG 840
++Y V +E+GE + T PD + + D + + + R + PI G
Sbjct: 13644 KEYTFRVSAENENGEGTPSEITVVARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPIKG 13703
Query: 841 YRIVYSPSVE--------GSSTELNLPETANSVTLS--DLQPGV--QYNITIYAVEENQE 888
+PSV + T +++ +A + TL D Q +Y IT+ V +E
Sbjct: 13704 KP---APSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKE 13760
Query: 889 STPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPV 944
T I + G P T P ++F EVT +T+ W PP+ S +T Y ++
Sbjct: 13761 GT---ISIKVVGKPGIPTGP----IKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRD- 13812
Query: 945 NLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKV-----FAVSHGRESKPLTAQQTTKL-D 998
++ + + T VT L G+ Y F+V + V G +S+P+ A+ + D
Sbjct: 13813 SVNNKWVTCASAVQKTTFRVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVPD 13872
Query: 999 APTNLQFVNETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGP-SVSKYPL 1053
AP V+ +V + WT P+ + ITGY L ++ N P + + +
Sbjct: 13873 APPPPNIVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTPIRMRDFKV 13932
Query: 1054 RNLQPASEYTVSLVAI------KGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITW 1107
L EY ++AI K + S + PG P +T ++ + W
Sbjct: 13933 TGLTEGLEYEFRVMAINLAGVGKPSLPSEPVVALDPIDPPGK---PEVINITRNSVTLIW 13989
Query: 1108 T-PAPRIGFKL-------GVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDG 1159
T P G KL PS+ V + V+ L G +Y + I+
Sbjct: 13990 TEPKYDGGHKLTGYIVEKRDLPSKSWMKANHVNVPECAFTVTDLVEGGKYEFRIRAKNTA 14049
Query: 1160 QERDAPIVN----------KVVTPLSPPT---NLHLEANPDTGVLTV-----------SW 1195
AP + + T + PT L ++A DT VL SW
Sbjct: 14050 GAISAPSESTETIICKDEYEAPTIVLDPTIKDGLTIKAG-DTIVLNAISILGKPLPKSSW 14108
Query: 1196 ERS----TTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVK 1251
++ DIT +IT+TPT+ +++ D T +P + K
Sbjct: 14109 SKAGKDIRPSDIT--QITSTPTSSML--TIKYATRKDAGEYTITATNP--------FGTK 14156
Query: 1252 DDKESVPISDTIIPEVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGEGIPI 1311
+ V + D +P P ++S +++ L WTP + ++ E +
Sbjct: 14157 VEHVKVTVLD--VPGPPGPVEIS--NVSAEKATLTWTPPLEDGGSPIKSYILEKRETSRL 14212
Query: 1312 FEDFVDSSVG--YYTVTGLEPGIDYDISVITLINGG-----ESAPTTLTQQTAVP-PPTD 1363
V + + T L G +Y V + + G +S P + + P PP
Sbjct: 14213 LWTVVSEDIQSCRHVATKLIQGNEYIFRVSAVNHYGKGEPVQSEPVKMVDRFGPPGPPEK 14272
Query: 1364 LRFTNIGPDTMRVTWAPP---PSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLL 1420
+N+ +T V+W P ++T + V K+ V + SD +T L
Sbjct: 14273 PEVSNVTKNTATVSWKRPVDDGGSEITGYHVERREKKSLRWVRAIKTPVSDLRCKVTGLQ 14332
Query: 1421 PGTEYVVSVSSVYEQHESTPLRGRQKTGLDS-------PTGIDFSDITANSFTVHWIAPR 1473
G+ Y VS+ P + P+ +D T S ++ W P
Sbjct: 14333 EGSTYEFRVSAENRAGIGPPSEASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLAWGKPH 14392
Query: 1474 ----ATITGYRIRHHPEHFSGRPREDRVPHSR-NSITLTNLTPGTEYVVSIVALN--GRE 1526
ITGY + H ++ R + +L +Y I A+N G
Sbjct: 14393 YDGGLEITGYVVEHQKVGDEAWIKDTTGTALRITQFVVPDLQTKEKYNFRISAINDAGVG 14452
Query: 1527 ESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFT 1586
E ++ + ++ D E+ A +L++ +++R + G P E T
Sbjct: 14453 EPAVIPDVEIVEREMAPDFELDAELRRTLVV---RAGLSIRIFVPIKGR-----PAPEVT 14504
Query: 1587 -VPGSKSTATISGLKPGVDYTITVYAVTGRGD---------SPASSKPISINYRTEIDKP 1636
+ + + ++ +T+ + R D +PA K +N R +D P
Sbjct: 14505 WTKDNINLKNRANIENTESFTLLIIPECNRYDTGKFVMTIENPAGKKSGFVNVRV-LDTP 14563
Query: 1637 S---QMQVTDVQDNSISVKW----LPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMT 1689
++ TD+ +S+++ W + S +T Y V T T +
Sbjct: 14564 GPVLNLRPTDITKDSVTLHWDLPLIDGGSRITNYIVEKREATRKS-YSTATTKCHKCTYK 14622
Query: 1690 IEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDR----PKGLAFTDVDVDSIKIAWES 1745
+ GL EY V A+N G +P T P L D+ ++ +AW
Sbjct: 14623 VTGLSEGCEYFFRVMAENEYGIGEPTETTEPVKASEAPSPPDSLNIMDITKSTVSLAWPK 14682
Query: 1746 PQ----GQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHD--- 1798
P+ +++ Y + G E ++ L G EYT V+A++
Sbjct: 14683 PKHDGGSKITGYVIEAQRKGSDQWTHITTVKGLE--CVVRNLTEGEEYTFQVMAVNSAGR 14740
Query: 1799 --DMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPM 1856
ES+P+I + T +P Q + + + + G R + T K G
Sbjct: 14741 SAPRESRPVIVKEQTMLPELDLRGIYQKLVIAKAGDNIKVEIPVLG-RPKPTVTWKKGDQ 14799
Query: 1857 -----KEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVS----- 1906
+ +N ++S +++ + + + Y LT+R G V + +
Sbjct: 14800 ILKQTQRVNFETTATSTILN-INECVRSDSGPY----PLTARNIVGEVGDVITIQVHDIP 14854
Query: 1907 --PPRRARVTDATETTITISWRTKTE----TITGFQVDAVPANGQTPIQRTIKPDVRSYT 1960
P + + + +T SW I+ + V+ + T ++ +Y
Sbjct: 14855 GPPTGPIKFDEVSSDFVTFSWDPPENDGGVPISNYVVEMRQTDSTTWVELATTVIRTTYK 14914
Query: 1961 ITGLQPGTDYKIYL-----YTLNDNARSSPVVIDASTAIDAPSNL-RFLATTPNSLLVSW 2014
T L G +Y+ + Y + S+ +V + + P + A T +S+ +SW
Sbjct: 14915 ATRLTTGLEYQFRVKAQNRYGVGPGITSACIVANYPFKVPGPPGTPQVTAVTKDSMTISW 14974
Query: 2015 QPP----RARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNN 2070
P + I GY ++ ++ + V + +GL G Y VIA
Sbjct: 14975 HEPLSDGGSPILGYHVERKERNGILWQTVSKALVPGNIFKSSGLTDGIAYEFRVIAENMA 15034
Query: 2071 QKSEP 2075
KS+P
Sbjct: 15035 GKSKP 15039
Score = 116 bits (291), Expect = 2e-25
Identities = 288/1381 (20%), Positives = 498/1381 (36%), Gaps = 191/1381 (13%)
Query: 766 LDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDT 825
+D + TS I + G K + ++ G+ ++ P + V + D
Sbjct: 6740 IDTTAEQTSFRILEAKKGDKGRYKIVLQNKHGKAEGFINLKVIDVPGPVRNLEVTETFDG 6799
Query: 826 SIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETAN-SVTLSDLQPG-VQYNIT 879
+ + W P + I GY +V ++ + L + T++ LQ G V+Y
Sbjct: 6800 EVSLAWEEPLTDGGSKIIGY-VVERRDIKRKTWVLATDRAESCEFTVTGLQKGGVEYLFR 6858
Query: 880 IYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVT 935
+ A PV + D P ++ +V V++ W PPE + +T
Sbjct: 6859 VSARNRVGTGEPVETDNPVEARSKYDVPGPPLNVTITDVNRFGVSLTWEPPEYDGGAEIT 6918
Query: 936 GYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTT 995
Y +++ + + A VT + G Y F+V A + KP A
Sbjct: 6919 NYVIELRDKTSIRWDTAMTVRAEDLSATVTDVVEGQEYSFRVRAQNRIGVGKPSAATPFV 6978
Query: 996 KL-------DAPTNLQFVNETDSTVLVRWTPP----RAQITGYRLTVGLTRRGQPR---- 1040
K+ P NL ++T S+V ++W PP + I GY + G+
Sbjct: 6979 KVADPIERPSPPVNLTSSDQTQSSVQLKWEPPLKDGGSPILGY--IIERCEEGKDNWIRC 7036
Query: 1041 QYNVGPSVSKYPLRNLQPASE--YTVSLVAIKGNQESPKATGVFTT----LQPGSSIPPY 1094
+ P ++ Y + L+ ++ Y VS G + + G T ++P + +
Sbjct: 7037 NMKLVPELT-YKVTGLEKGNKYLYRVSAENKAGVSDPSEILGPLTADDAFVEPTMDLSAF 7095
Query: 1095 NTEV-----TETTIVI--TWTPAPRIGFKLGVRPSQGGEAPREVT-SDSGSIVVSGLTPG 1146
+ TI++ T P P + G + + G+ + T S +V+S
Sbjct: 7096 KDGLEVIVPNPITILVPSTGYPRPTATWCFGDKVLETGDRVKMKTLSAYAELVISPSERS 7155
Query: 1147 VEYVYTIQVLRDGQERDAPI-VNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPD--- 1202
+ +YT+++ + I VN + P +P + D+ LT WE PD
Sbjct: 7156 DKGIYTLKLENRVKTISGEIDVNVIARPSAPKELKFGDITKDSVHLT--WE---PPDDDG 7210
Query: 1203 ---ITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSV------------ 1247
+TGY + + + + + V T +L G EY V
Sbjct: 7211 GSPLTGYVVEKREVSRKTWTKVMDFV--TDLEFTVPDLVQGKEYLFKVCARNKCGPGEPA 7268
Query: 1248 YTVKDDKESVPISDTIIPEVPQLTDLSFVDITDSSIGLRWTPLNS---STIIGYRITVVA 1304
Y + S P + +P+ P+ ++ + D T +SI L W P + S I GY +
Sbjct: 7269 YVDEPVNMSTPAT---VPDPPE--NVKWRDRTANSIFLTWDPPKNDGGSRIKGYIVERCP 7323
Query: 1305 AGE------GIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQ--- 1355
G G P+ E ++ VTGLE G Y V L G S P+ T++
Sbjct: 7324 RGSDKWVACGEPVAETKME-------VTGLEEGKWYAYRVKALNRQGASKPSRPTEEIQA 7376
Query: 1356 --TAVPPPTDLRFTNIGPDTMR----------VTWAPPPSIDLTNFLVRYSPVKNEEDVA 1403
T P L + T++ VT P P I T + + ++
Sbjct: 7377 VDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWT----KADMILKQDKRI 7432
Query: 1404 ELSISPSDNAVVLTNLL---PGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDI 1460
+ P + V + + GT + +V+ + K G P D +D+
Sbjct: 7433 TIENVPKKSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNVLDKPG--PPAAFDITDV 7490
Query: 1461 TANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRNS------ITLTNLT 1510
T S + W PR + IT Y + R + V H +S T L
Sbjct: 7491 TNESCLLTWNPPRDDGGSKITNYVVER-------RATDSEVWHKLSSTVKDTNFKATKLI 7543
Query: 1511 PGTEYVVSIVALN------GREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAP-- 1562
P EY+ + A N + SP+ Q P LE T ++ ++W P
Sbjct: 7544 PNKEYIFRVAAENMYGVGEPVQASPITAKYQFDPPGPPTRLEPSDITKDAVTLTWCEPDD 7603
Query: 1563 --AVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYA--VTGRGDS 1618
+ Y + + + V+ +P +T + GL Y V A + G G
Sbjct: 7604 DGGSPITGYWVERLDPDTDKWVRCNKMPVKDTTYRVKGLTNKKKYRFRVLAENLAGPGKP 7663
Query: 1619 PASSKPISINYRTEID---KPSQMQVTDVQDNSISVKWL----PSSSPVTGYRVTTTPKN 1671
S++PI I + ID P + V DV S+ + W + + Y V K
Sbjct: 7664 SKSTEPILI--KDPIDPPWPPGKPTVKDVGKTSVRLNWTKPEHDGGAKIESY-VIEMLKT 7720
Query: 1672 GPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQP-------LVQTAVTNID 1724
G G T+ + GL EY V A N +GES+P L + +
Sbjct: 7721 GTDEWVRVAEGVPTTQHLLPGLMEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPS 7780
Query: 1725 RPKGLAFTDVDVDSIKIAWESPQ----GQVSRYRVTYSSPEDGIHELFPAPDG--EEDTA 1778
P+ L ++ ++ + W P+ ++ Y V D + + D ++
Sbjct: 7781 PPRWLEVINITKNTADLKWTVPEKDGGSPITNYIV---EKRDVRRKGWQTVDTTVKDTKC 7837
Query: 1779 ELQGLRPGSEYTVSVVAL-------HDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSA 1831
+ L GS Y V A + ++E L T P L VT +
Sbjct: 7838 TVTPLTEGSLYVFRVAAENAIGQSDYTEIEDSVLAKDTFTTPGPPYALAVVDVTKRHVDL 7897
Query: 1832 QWTPPNVQ--LTGYRVRVTPKEKTGP--MKEINLAPDSSSVVVSGLMVATKYEVSVYALK 1887
+W PP R + KE+ G +K A + V+ ++ T+ + V A
Sbjct: 7898 KWEPPKNDGGRPIQRYVIEKKERLGTRWVKAGKTAGPDCNFRVTDVIEGTEVQFQVRAEN 7957
Query: 1888 DTLTSRPAQGV-VTTLEN----VSPPRRARVTDATETTITISWRTKTET----ITGFQVD 1938
+ P++ + ++E+ SPP VTDA I I+W+ + I G+ V+
Sbjct: 7958 EAGVGHPSEPTEILSIEDPTSPPSPPLDLHVTDAGRKHIAIAWKPPEKNGGSPIIGYHVE 8017
Query: 1939 AVPANGQTPIQRTIKP--DVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDA 1996
P + ++ +P D++ G+ P +Y + + +N S P I +
Sbjct: 8018 MCPVGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAIGVSEPSEISENVVAKD 8077
Query: 1997 P 1997
P
Sbjct: 8078 P 8078
Score = 115 bits (287), Expect = 7e-25
Identities = 286/1430 (20%), Positives = 524/1430 (36%), Gaps = 172/1430 (12%)
Query: 785 KYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPT-VDQVDDTSIVVRWSRPQ----APIT 839
+Y++ + ++ G +S+ ++ P P P ++ + + W RPQ A I
Sbjct: 19554 QYVLTLKNVA--GTRSVAVNCKVLDKPGPPAGPLEINGLTAEKCSLSWGRPQEDGGADID 19611
Query: 840 GYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETT 899
Y + + + T S ++ L G +Y + V + P+ E+
Sbjct: 19612 YYIVEKRETSHLAWTICEGELQMTSCKVTKLLKGNEYIFRVTGVNKYGVGEPL----ESV 19667
Query: 900 GTPRSD--TVPSP-RDLQFVEVTDVKVTIMWTPPES----AVTGYRVDVIPVN-LPGEHG 951
D TVPSP L+ VT +T+ W+ PES ++GY ++ N L
Sbjct: 19668 AIKALDPFTVPSPPTSLEITSVTKESMTLCWSRPESDGGSEISGYIIERREKNSLRWVRV 19727
Query: 952 QRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNL-------Q 1004
+ P+ + + TGL G Y ++V+A + S P + + P L +
Sbjct: 19728 NKKPVY-DLRVKSTGLREGCEYEYRVYAENAAGLSLPSETSPLIRAEDPVFLPSPPSKPK 19786
Query: 1005 FVNETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPAS 1060
V+ +T+ + W P A ITGY + + + ++Y + L +
Sbjct: 19787 IVDSGKTTITIAWVKPLFDGGAPITGYTVEYKKSDDTDWKTSIQSLRGTEYTISGLTTGA 19846
Query: 1061 EYTVSLVAIK---GNQESPKATGVFTTLQPGSSIPPYNTEVTETTIV-----ITWT---- 1108
EY + ++ + S + + + ++E+ +T IV T T
Sbjct: 19847 EYVFRVKSVNKVGASDPSDSSDPQIAKEREEEPLFDIDSEMRKTLIVKAGASFTMTVPFR 19906
Query: 1109 --PAPRIGFKLGVRPSQG--GEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDA 1164
P P + L +P A + T S+ + YT+ +
Sbjct: 19907 GRPVPNV---LWSKPDTDLRTRAYVDTTDSRTSLTIENANRNDSGKYTLTIQNVLSAASL 19963
Query: 1165 PIVNKVVTPLSPPTNLHLE-ANPDTGVLTVSW---ERSTTPDITGYRITTTPTNGQQGNS 1220
+V KV+ PPTN+ ++ ++ VL SW E + Y I + + S
Sbjct: 19964 TLVVKVLDTPGPPTNITVQDVTKESAVL--SWDVPENDGGAPVKNYHIEKREASKKAWVS 20021
Query: 1221 LE--------EVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPEVPQLTD 1272
+ +V + + + + +S E+ V + + KE V I++ P P+
Sbjct: 20022 VTNNCNRLSYKVTNLQEGAIYYFRVSGENEFGVGIPA--ETKEGVKITEK--PSPPE--K 20075
Query: 1273 LSFVDITDSSIGLRWTPLN---SSTIIGYRITVVAAGEGIPIFEDFVDSSVG---YYTVT 1326
L I+ S+ L W S I+ Y + + G+ +++V +V ++ V+
Sbjct: 20076 LGVTSISKDSVSLTWLKPEHDGGSRIVHYVVEALEKGQ-----KNWVKCAVAKSTHHVVS 20130
Query: 1327 GLEPGIDYDISVITLINGGESAPT-----TLTQQTAVPPPTDLRFTNIGPDTMRVTWAPP 1381
GL +Y V G S P L ++ PP D++ N T+ V
Sbjct: 20131 GLRENSEYFFRVFAENQAGLSDPRELLLPVLIKEQLEPPEIDMK--NFPSHTVYVRAGSN 20188
Query: 1382 PSIDLTNFLVRYSPVKNEEDVAELSISPSDNA-VVLTNLLPGTEYVVSVSSVYEQHESTP 1440
+D+ V D L + N + NL + V+ + + +
Sbjct: 20189 LKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADAGRYEITAAN 20248
Query: 1441 LRGRQKTGLD--------SPTG-IDFSDITANSFTVHWIAPR----ATITGYRIRHHPEH 1487
G K ++ PTG + SDIT S T+ W P+ + +T Y + E
Sbjct: 20249 SSGTTKAFINIVVLDRPGPPTGPVVISDITEESVTLKWEPPKYDGGSQVTNYILLKR-ET 20307
Query: 1488 FSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGR------EESPLLIGQQSTVSDV 1541
+ E +R + + LT G EY I A N + + + + T
Sbjct: 20308 STAVWTEVSATVARTMMKVMKLTTGEEYQFRIKAENRFGISDHIDSACVTVKLPYTTPGP 20367
Query: 1542 PRDLEVVAATPTSLLISWDAPAVT----VRYYRITYGETGGNSPVQEFTVPGSKSTATIS 1597
P V T S+ + W P V Y + + + + + ++
Sbjct: 20368 PSTPWVTNVTRESITVGWHEPVSNGGSAVVGYHLEMKDRNSILWQKANKLVIRTTHFKVT 20427
Query: 1598 GLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKW---- 1653
+ G+ Y VYA G S + + P +++TD+ NS+S+ W
Sbjct: 20428 TISAGLIYEFRVYAENAAGVGKPSHPSEPVLAIDACEPPRNVRITDISKNSVSLSWQQPA 20487
Query: 1654 LPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE-S 1712
S +TGY V TK +T+ I GL +Y V+A+N G S
Sbjct: 20488 FDGGSKITGYIVERRDLPDGRWTKASFTNVTETQFIISGLTQNSQYEFRVFARNAVGSIS 20547
Query: 1713 QPL-VQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAP 1771
P V +T ID G D+ ++ ++ + G + R S E +
Sbjct: 20548 NPSEVVGPITCIDSYGGPVI-DLPLEYTEVV-KYRAGTSVKLRAGISGKPAPTIEWYK-D 20604
Query: 1772 DGEEDTAELQGLRPGSEYTVSVVALHDDMES-------QPLIGTQSTAI---------PA 1815
D E T L + ++ ++ D + S + +G+ S I P
Sbjct: 20605 DKELQTNALVCVENTTDLASILIKDADRLNSGCYELKLRNAMGSASATIRVQILDKPGPP 20664
Query: 1816 PTDLKFTQVTPTSLSAQWTPP----NVQLTGYRVRVTPKEKTGPM--KEINLAPDSSSVV 1869
++F VT ++ W PP ++T Y + K +T + ++ + +
Sbjct: 20665 GGPIEFKTVTAEKITLLWRPPADDGGAKITHY---IVEKRETSRVVWSMVSEHLEECIIT 20721
Query: 1870 VSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENV----SPPRRARVTDATETTITISW 1925
+ ++ +Y V A+ P + +N PP VT T+ ++T+ W
Sbjct: 20722 TTKIIKGNEYIFRVRAVNKYGIGEPLESDSVVAKNAFVTPGPPGIPEVTKITKNSMTVVW 20781
Query: 1926 RTKT----ETITGFQV---DAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLN 1978
I+G+ + D ++ TI+ D R +TGL +DY+ + +N
Sbjct: 20782 SRPIADGGSDISGYFLEKRDKKSLGWFKVLKETIR-DTRQ-KVTGLTENSDYQYRVCAVN 20839
Query: 1979 DNAR---SSPVVI-DASTAIDAP---SNLRFLATTPNSLLVSWQPP----RARITGYIIK 2027
+ S P A+ ID P + +R +T +S+ + W P + +TGY+++
Sbjct: 20840 AAGQGPFSEPSEFYKAADPIDPPGPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVVE 20899
Query: 2028 YEKPGSPPREVVP-RPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPL 2076
+ V + TE ++ L+PG Y V A+ + EP+
Sbjct: 20900 IRQGEEEEWTTVSTKGEVRTTEYVVSNLKPGVNYYFRVSAVNCAGQGEPI 20949
Score = 114 bits (286), Expect = 9e-25
Identities = 308/1475 (20%), Positives = 520/1475 (35%), Gaps = 204/1475 (13%)
Query: 806 SQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ----APITGYRIVYSPSVEGS-STELNLPE 860
S+ P P + T+ V+ + + W P+ A IT Y I T + +
Sbjct: 6881 SKYDVPGPPLNVTITDVNRFGVSLTWEPPEYDGGAEITNYVIELRDKTSIRWDTAMTVRA 6940
Query: 861 TANSVTLSDLQPGVQYNITIYA-----VEENQESTPVVIQQETTGTPRSDTVPSPRDLQF 915
S T++D+ G +Y+ + A V + +TP V + P P +L
Sbjct: 6941 EDLSATVTDVVEGQEYSFRVRAQNRIGVGKPSAATPFVKVADPIERPSP-----PVNLTS 6995
Query: 916 VEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGV 971
+ T V + W PP S + GY ++ + + +VTGL G
Sbjct: 6996 SDQTQSSVQLKWEPPLKDGGSPILGYIIERCEEGKDNWIRCNMKLVPELTYKVTGLEKGN 7055
Query: 972 TYYFKVFAVSHGRESKP------LTA-----QQTTKLDA-PTNLQFVNETDSTVLVRWTP 1019
Y ++V A + S P LTA + T L A L+ + T+LV T
Sbjct: 7056 KYLYRVSAENKAGVSDPSEILGPLTADDAFVEPTMDLSAFKDGLEVIVPNPITILVPSTG 7115
Query: 1020 -PRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKA 1078
PR T L + + ++S Y + P+ + +K
Sbjct: 7116 YPRPTATWCFGDKVLETGDRVKM----KTLSAYAELVISPSERSDKGIYTLKLENRVKTI 7171
Query: 1079 TG---VFTTLQPGSSIPPYNTEVTETTIVITWTP------APRIGFKLGVRPSQGGEAPR 1129
+G V +P + ++T+ ++ +TW P +P G+ + R E R
Sbjct: 7172 SGEIDVNVIARPSAPKELKFGDITKDSVHLTWEPPDDDGGSPLTGYVVEKR-----EVSR 7226
Query: 1130 EVTSDSGSIV------VSGLTPGVEYVYTIQVLRDGQERDAPIVNKVV---TPLS---PP 1177
+ + V V L G EY++ + + V++ V TP + PP
Sbjct: 7227 KTWTKVMDFVTDLEFTVPDLVQGKEYLFKVCARNKCGPGEPAYVDEPVNMSTPATVPDPP 7286
Query: 1178 TNLHLEANPDTGVLTVSWERSTTPD---ITGYRITTTPTNGQQGNSLEEVVHADQSSCTF 1234
N+ + ++W+ I GY + P + + E V + T
Sbjct: 7287 ENVKWRDRTANSIF-LTWDPPKNDGGSRIKGYIVERCPRGSDKWVACGEPVAETKMEVT- 7344
Query: 1235 DNLSPGLEYNVSVYTVKDDKESVPISDT-------------IIPEVPQLTDLSF-----V 1276
L G Y V + S P T I +V L L+ +
Sbjct: 7345 -GLEEGKWYAYRVKALNRQGASKPSRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKI 7403
Query: 1277 DITDSSIG-----LRWTPLNSSTIIGYRITVVAAGEGIP-----IFEDFVDSSVGYYTVT 1326
++ + G + WT + RIT+ E +P D S G Y +
Sbjct: 7404 ELPATVTGKPEPKITWTKADMILKQDKRITI----ENVPKKSTVTIVDSKRSDTGTYIIE 7459
Query: 1327 GLEPGIDYDISVITLINGGESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAPPPS--- 1383
+ + G +A + PP T++ ++ +TW PP
Sbjct: 7460 AVN------------VCGRATAVVEVNVLDKPGPPAAFDITDVTNESCLLTWNPPRDDGG 7507
Query: 1384 IDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSS-----VYEQHES 1438
+TN++V +E +LS + D T L+P EY+ V++ V E ++
Sbjct: 7508 SKITNYVVERRATDSEV-WHKLSSTVKDTNFKATKLIPNKEYIFRVAAENMYGVGEPVQA 7566
Query: 1439 TPLRGR-QKTGLDSPTGIDFSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPR 1493
+P+ + Q PT ++ SDIT ++ T+ W P + ITGY + R
Sbjct: 7567 SPITAKYQFDPPGPPTRLEPSDITKDAVTLTWCEPDDDGGSPITGYWVERLDPDTDKWVR 7626
Query: 1494 EDRVPHSRNSITLTNLTPGTEYVVSIVALN-------GREESPLLIGQQSTVSDVPRDLE 1546
+++P + + LT +Y ++A N + P+LI P
Sbjct: 7627 CNKMPVKDTTYRVKGLTNKKKYRFRVLAENLAGPGKPSKSTEPILIKDPIDPPWPPGKPT 7686
Query: 1547 VVAATPTSLLISWDAP----AVTVRYYRITYGETGGNSPVQEFTVPGSKSTA-TISGLKP 1601
V TS+ ++W P + Y I +TG + V+ G +T + GL
Sbjct: 7687 VKDVGKTSVRLNWTKPEHDGGAKIESYVIEMLKTGTDEWVR--VAEGVPTTQHLLPGLME 7744
Query: 1602 GVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQ---MQVTDVQDNSISVKWL---- 1654
G +Y+ V AV G+S S + R ++ PS ++V ++ N+ +KW
Sbjct: 7745 GQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLEVINITKNTADLKWTVPEK 7804
Query: 1655 PSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQ- 1713
SP+T Y V G T D T+ T+ L YV V A+N G+S
Sbjct: 7805 DGGSPITNYIVEKRDVRRKGWQTVDTTVKD-TKCTVTPLTEGSLYVFRVAAENAIGQSDY 7863
Query: 1714 ------PLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQ----VSRYRVTYSSPEDG 1763
L + T P LA DV + + WE P+ + RY +
Sbjct: 7864 TEIEDSVLAKDTFTTPGPPYALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKERLGT 7923
Query: 1764 IHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPT------ 1817
G + + + G+E V A ++ P T+ +I PT
Sbjct: 7924 RWVKAGKTAGPDCNFRVTDVIEGTEVQFQVRAENEAGVGHPSEPTEILSIEDPTSPPSPP 7983
Query: 1818 -DLKFTQVTPTSLSAQWTPPNVQ----LTGYRVRVTPKEKTGPMKEINLAP--DSSSVVV 1870
DL T ++ W PP + GY V + P T +N P D V
Sbjct: 7984 LDLHVTDAGRKHIAIAWKPPEKNGGSPIIGYHVEMCP-VGTEKWMRVNSRPIKDLKFKVE 8042
Query: 1871 SGLMVATKYEVSVYALKDTLTSRP---AQGVVTTLENVSP-----PRRARVTDATETTIT 1922
G++ +Y + V A+ S P ++ VV + P V + + +I
Sbjct: 8043 EGVVPDKEYVLRVRAVNAIGVSEPSEISENVVAKDPDCKPTIDLETHDIIVIEGEKLSIP 8102
Query: 1923 ISWRTKTETITGFQVDAVPANGQTPIQRTIKPD-VRSYTITGLQPGTDYKIYLYTLNDNA 1981
+ +R + D + T+K D + ++ D IY TL +
Sbjct: 8103 VPFRAVPVPTVSWHKDGKEVKASDRL--TMKNDHISAHLEVPKSVRADAGIYTITLENKL 8160
Query: 1982 RSSPVVIDAST-AIDAP-SNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPP 2035
S+ I+ + P +++ T +S ++W+PP I Y+++ + G
Sbjct: 8161 GSATASINVKVIGLPGPCKDIKASDITKSSCKLTWEPPEFDGGTPILHYVLERREAGR-- 8218
Query: 2036 REVVP-RPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELPQLVTLPHP 2094
R +P T+ L P EY V A+ +G + EL V P
Sbjct: 8219 RTYIPVMSGENKLSWTVKDLIPNGEYFFRVKAVNK-------VGGGEYIELKNPVIAQDP 8271
Query: 2095 NLHGPEILDV----PSTVQKTPFVTHPGYDTGNGI 2125
+DV P+ T P YD G+ I
Sbjct: 8272 KQPPDPPVDVEVHNPTAEAMTITWKPPLYDGGSKI 8306
Score = 114 bits (286), Expect = 9e-25
Identities = 280/1356 (20%), Positives = 495/1356 (36%), Gaps = 217/1356 (16%)
Query: 727 SVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQ--YLDLPSTA--TSVNIPDLLP 782
+VTE+T+ V+SW D G ++++ + ++ + + + ++ S T + + LL
Sbjct: 15258 AVTEVTSEKCVLSWFPPLDD-GGAKIDHYIVQKRETSRLAWTNVASEVQVTKLKVTKLLK 15316
Query: 783 GRKYI-----VNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAP 837
G +YI VN Y + E E +L+ + PD P +P V + S+VV W P +
Sbjct: 15317 GNEYIFRVMAVNKYGVGEPLESEPVLAVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDS- 15375
Query: 838 ITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQ-------PGVQYNITIYAVEENQEST 890
G + + VE N TL+DL+ G +Y I A S
Sbjct: 15376 -DGGSEIINYIVERRDKAGQRWIKCNKKTLTDLRYKVSGLTEGHEYEFRIMAENAAGISA 15434
Query: 891 PVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNL 946
P P + + ++ + ++I W P S +TGY V++ L
Sbjct: 15435 PSPTSPFYKACDTVFKPGPPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIA---L 15491
Query: 947 PGEHGQRLPIS----RNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLD---A 999
P E ++ + T +TGL+ Y +++A++ +P T K +
Sbjct: 15492 PEEDEWQIVTPPAGLKATSYTITGLTENQEYKIRIYAMNSEGLGEPALVPGTPKAEDRML 15551
Query: 1000 PTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPR---QYNVGPSVSKYPLRNL 1056
P ++ + V +R RL V + R P + G S+ K ++
Sbjct: 15552 PPEIELDADLRKVVTIR------ACCTLRLFVPIKGRPAPEVKWARDHGESLDK---ASI 15602
Query: 1057 QPASEYTVSLVAIKGNQESPK----------ATGVFTTLQ----PGSSIPPYNTEVTETT 1102
+ S YT+ +V +S K + F ++ PG EVT+T+
Sbjct: 15603 ESTSSYTLLIVGNVNRFDSGKYILTVENSSGSKSAFVNVRVLDTPGPPQDLKVKEVTKTS 15662
Query: 1103 IVITWTPAPRI--GFKLGVRPSQGGEAPREVTS------DSGSIVVSGLTPGVEYVYTIQ 1154
+ +TW P P + G K+ + E+ R+ S S V L G Y + +
Sbjct: 15663 VTLTWDP-PLLDGGSKIKNYIVEKRESTRKAYSTVATNCHKTSWKVDQLQEGCSYYF--R 15719
Query: 1155 VLRDGQ------ERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPD---ITG 1205
VL + + A V PL P ++ ++ +++SWE+ I G
Sbjct: 15720 VLAENEYGIGLPAETAESVKASERPLPPGKITLMDVTRNS--VSLSWEKPEHDGGSRILG 15777
Query: 1206 YRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYT-----VKDDKE-SVPI 1259
Y I T G + V +++ T L G EY+ V + D ++ SVP+
Sbjct: 15778 Y-IVEMQTKGSDKWATCATVKVTEATIT--GLIQGEEYSFRVSAQNEKGISDPRQLSVPV 15834
Query: 1260 --SDTIIPEVPQLTDLSFVDITDSSI------------GLRW----TPLNSSTIIGYRIT 1301
D +IP +L +F + + + W PL +T + T
Sbjct: 15835 IAKDLVIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAEST 15894
Query: 1302 VVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTL---TQQTAV 1358
+ +D VG+Y V+ L N A TL
Sbjct: 15895 ---ENNSLLTIKDACREDVGHY--------------VVKLTNSAGEAIETLNVIVLDKPG 15937
Query: 1359 PPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAE---LSISPSDNAVV 1415
PP ++ + D++ ++W PP D + + Y K + +S + + +
Sbjct: 15938 PPTGPVKMDEVTADSITLSWG-PPKYDGGSSINNYIVEKRDTSTTTWQIVSATVARTTIK 15996
Query: 1416 LTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTG-----LDSPTGIDFSDITA-NSFTVHW 1469
L G EY +++ +ST L + P G +++ +S V W
Sbjct: 15997 ACRLKTGCEYQFRIAAENRYGKSTYLNSEPTVAQYPFKVPGPPGTPVVTLSSRDSMEVQW 16056
Query: 1470 IAP----RATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGR 1525
P + + GY + + + ++ P + T L G EY + A
Sbjct: 16057 NEPISDGGSRVIGYHLERKERNSILWVKLNKTPIPQTKFKTTGLEEGVEYEFRVSA---- 16112
Query: 1526 EESPLLIGQQSTVSD--VPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQ 1583
E+ + IG+ S VS+ V RD P +++++ + +VT+++ + TY G S +
Sbjct: 16113 -ENIVGIGKPSKVSECYVARDPCDPPGRPEAIIVTRN--SVTLQWKKPTY---DGGSKIT 16166
Query: 1584 EFTVPGS--------KSTAT--------ISGLKPGVDYTITVYAVTGRG-DSPASSKPIS 1626
+ V K++ T ++GL Y V A G S S +
Sbjct: 16167 GYIVEKKELPEGRWMKASFTNIIDTHFEVTGLVEDHRYEFRVIARNAAGVFSEPSESTGA 16226
Query: 1627 INYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQT 1686
I R E+D P +D + ++V P PT G +
Sbjct: 16227 ITARDEVDPPRISMDPKYKDTIV-------VHAGESFKVDADIYGKPIPTIQWIKGDQEL 16279
Query: 1687 EMTIEGLQPTVEYVVS---------------VYAQNPSGESQPLVQTAVTNIDRP----K 1727
T + ++ S + A+N +GE V V +DRP
Sbjct: 16280 SNTARLEIKSTDFATSLSVKDAVRVDSGNYILKAKNVAGERSVTVNVKV--LDRPGPPEG 16337
Query: 1728 GLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHEL-FPAPDGEEDT--AELQGLR 1784
+ + V + +AW+ P + Y L + D T ++ L
Sbjct: 16338 PVVISGVTAEKCTLAWKPPLQDGGSDIINYIVERRETSRLVWTVVDANVQTLSCKVTKLL 16397
Query: 1785 PGSEYTVSVVALH-----DDMESQPLIGTQSTAIP-APTDLKFTQVTPTSLSAQWTPP-- 1836
G+EYT ++A++ + +ES+P++ +P AP + T VT S+ W P
Sbjct: 16398 EGNEYTFRIMAVNKYGVGEPLESEPVVAKNPFVVPDAPKAPEVTTVTKDSMIVVWERPAS 16457
Query: 1837 --NVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRP 1894
++ GY + KE + + V+GL+ YE V A S P
Sbjct: 16458 DGGSEILGYVLEKRDKEGIRWTRCHKRLIGELRLRVTGLIENHDYEFRVSAENAAGLSEP 16517
Query: 1895 A-----QGVVTTLENVSPPRRARVTDATETTITISW 1925
+ Q + PP +V D T +++ +SW
Sbjct: 16518 SPPSAYQKACDPIYKPGPPNNPKVIDITRSSVFLSW 16553
Score = 114 bits (284), Expect = 2e-24
Identities = 358/1658 (21%), Positives = 597/1658 (36%), Gaps = 251/1658 (15%)
Query: 607 SSSGPVEVFIT----ETPSQPNSHPIQWNAPQPSHISKYILRWRP---------KNSVGR 653
+SSG F+T +TP P + ++ + L W P KN V
Sbjct: 17794 NSSGSKSAFVTVKVLDTPGPPQNLAVKEVRKDSA-----FLVWEPPIIDGGAKVKNYVID 17848
Query: 654 WKEATIPGHLN--------SYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTP 705
+E+T + N S+ ++ L G +Y ++++ ++G P
Sbjct: 17849 KRESTRKAYANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFG-------------VGVP 17895
Query: 706 VTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVS----ASDTVSGFRVEYELSEEGD 761
V + P SP ++T+++ +S + W V G+ VE + +G
Sbjct: 17896 VETVDAVKAAEPPSP--PGKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVE--MQPKGT 17951
Query: 762 EPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQ 821
E + S + + L G++Y V +E G+ + A D P++
Sbjct: 17952 EKWSIVAESKVCNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKL 18011
Query: 822 VDDTSIVVRWS--RPQAPITGY-RIVYSPSVEGS----STELNLPETANSVTLSDLQPGV 874
+T + + + P+ G R S +G +T +N+ ETA S L ++ G
Sbjct: 18012 PFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLH-IKEGN 18070
Query: 875 QYNITIYAVEENQESTPV-----VIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTP 929
+ + Y V + VI E G P ++F EV+ V I W P
Sbjct: 18071 KDDFGKYTVTATNSAGTATENLSVIVLEKPGPPVGP-------VRFDEVSADFVVISWEP 18123
Query: 930 PESA----VTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRE 985
P ++ Y V+ H ++R T ++T L G Y F++FA + +
Sbjct: 18124 PAYTGGCQISNYIVEKRDTTTTTWHMVSATVARTTI-KITKLKTGTEYQFRIFAENRYGK 18182
Query: 986 SKPLTA-----QQTTKLDAPTNLQFVNE-TDSTVLVRWTPP----RAQITGYRLTVGLTR 1035
S PL + Q K P FV + +LV+W P +I GY L
Sbjct: 18183 SAPLDSKAVIVQYPFKEPGPPGTPFVTSISKDQMLVQWHEPVNDGGTKIIGYHLEQKEKN 18242
Query: 1036 RGQPRQYNVGP-SVSKYPLRNLQPASEY--TVSLVAIKGNQESPKATGVFTTLQPGSSIP 1092
+ N P +K+ L EY VS I G + K + F P P
Sbjct: 18243 SILWVKLNKTPIQDTKFKTTGLDEGLEYEFKVSAENIVGIGKPSKVSECFVARDPCD--P 18300
Query: 1093 PYNTE---VTETTIVITW-TPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVE 1148
P E +T + + W PA G K+ G + G + + T +E
Sbjct: 18301 PGRPEAIVITRNNVTLKWKKPAYDGGSKI------TGYIVEKKDLPDGRWMKASFTNVLE 18354
Query: 1149 YVYTIQVLRDGQERDAPIV-NKVVTPLSPPT---------------NLHLEAN-PDTGVL 1191
+T+ L + Q + ++ S P+ N L+ D V+
Sbjct: 18355 TEFTVSGLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARDEIDAPNASLDPKYKDVIVV 18414
Query: 1192 TVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNL---------SPGLE 1242
DI G I + + G LEE + T + G +
Sbjct: 18415 HAGETFVLEADIRGKPIPDVVWS-KDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQ 18473
Query: 1243 YNVSVYTVKDDKESVPISDTIIPEV-PQLTDLSFVDITDSSIGLRWTP--LNSSTIIGYR 1299
Y + + V K S+PI+ ++ P L +T L W P + I +
Sbjct: 18474 YILKLSNVGGTK-SIPITVKVLDRPGPPEGPLKVTGVTAEKCYLAWNPPLQDGGANISHY 18532
Query: 1300 ITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGG-----ESAPTTLTQ 1354
I + + + Y VT L PG +Y V+ + G ES P T
Sbjct: 18533 IIEKRETSRLSWTQVSTEVQALNYKVTKLLPGNEYIFRVMAVNKYGIGEPLESGPVTACN 18592
Query: 1355 QTAVP-PPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISP---S 1410
P PP+ + I D+M VTWA P T +++E V + +
Sbjct: 18593 PYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDKEGVRWTKCNKKTLT 18652
Query: 1411 DNAVVLTNLLPGTEYVVSVSS-----VYEQHESTPLRGRQKTGL---DSPTGIDFSDITA 1462
D + +T L G Y V++ V E E + R L P+ +D +
Sbjct: 18653 DLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFY-RACDALYPPGPPSNPKVTDTSR 18711
Query: 1463 NSFTVHWIAP----RATITGYRIRHHPEHFSGRPREDRVPHS---RNSITLTNLTPGTEY 1515
+S ++ W P A + GY + + + P + T+T L TEY
Sbjct: 18712 SSVSLAWSKPIYDGGAPVKGYVV--EVKEAAADEWTTCTPPTGLQGKQFTVTKLKENTEY 18769
Query: 1516 VVSIVALN--GREESPLLIGQQSTVSDV-PRDLEVVAATPTSLLISWDAPAVTVRYYRIT 1572
I A+N G E L G + P ++E+ A +++ A T+R +
Sbjct: 18770 NFRICAINSEGVGEPATLPGSVVAQERIEPPEIELDADLRKVVVLRASA---TLRLFVTI 18826
Query: 1573 YGETGGNSPVQEFTVPGSKSTAT-ISGLKPGVDYTITVYAVTGRGDS---------PASS 1622
G P E ++ T + ++ +T+ V R DS + S
Sbjct: 18827 KGR-----PEPEVKWEKAEGILTDRAQIEVTSSFTMLVIDNVTRFDSGRYNLTLENNSGS 18881
Query: 1623 KPISINYRTEIDKPS---QMQVTDVQDNSISVKWLP----SSSPVTGYRV---TTTPKNG 1672
K +N R +D PS + + +V+ +S+++ W P + +T Y V TT K
Sbjct: 18882 KTAFVNVRV-LDSPSAPVNLTIREVKKDSVTLSWEPPLIDGGAKITNYIVEKRETTRK-- 18938
Query: 1673 PGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPK----G 1728
T T +T IE LQ Y V A N G P T + P
Sbjct: 18939 --AYATITNNCTKTTFRIENLQEGCSYYFRVLASNEYGIGLPAETTEPVKVSEPPLPPGR 18996
Query: 1729 LAFTDVDVDSIKIAWESPQ----GQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLR 1784
+ DV ++ I WE P+ +++ Y V + G + + A + GL
Sbjct: 18997 VTLVDVTRNTATIKWEKPESDGGSKITGYVVEMQT--KGSEKWSTCTQVKTLEATISGLT 19054
Query: 1785 PGSEYTVSVVALHDDMESQPL-----IGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQ 1839
G EY V A+++ S P + + I +L F T + + +V
Sbjct: 19055 AGEEYVFRVAAVNEKGRSDPRQLGVPVIARDIEIKPSVELPFH--TFNVKAREQLKIDVP 19112
Query: 1840 LTGYRVRVTPKEKTG-PMKEINLAPDSSSVVVSGLMV--ATKYEVSVYAL--KDTLTSRP 1894
G K G +KE SSS V+ L + A+K +V Y L ++ S
Sbjct: 19113 FKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSNSAGSIT 19172
Query: 1895 AQGVVTTLENVSPPRRARVTDATETTITISWRTKTE----TITGFQVDAVPANGQT---- 1946
+ L+ PP R+ + + +ITISW I+ + V+ T
Sbjct: 19173 VPITIIVLDRPGPPGPIRIDEVSCDSITISWNPPEYDGGCQISNYIVEKKETTSTTWHIV 19232
Query: 1947 --PIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDA-------- 1996
+ RT S I L G++Y+ + N +SS S+A+ A
Sbjct: 19233 SQAVART------SIKIVRLTTGSEYQFRVCAENRYGKSS---YSESSAVVAEYPFSPPG 19283
Query: 1997 -PSNLRFLATTPNSLLVSWQPP----RARITGYIIKYEKPGSPPREVVPRPRPGVTEATI 2051
P + + T +++LV+WQ P +R+ GY ++Y++ S + T+ +
Sbjct: 19284 PPGTPKVVHATKSTMLVTWQVPVNDGGSRVIGYHLEYKERSSILWSKANKILIADTQMKV 19343
Query: 2052 TGLEPGT--EYTIYVIAL----KNNQKSEPLIGRKKTD 2083
+GL+ G EY +Y + K ++ EP+ R D
Sbjct: 19344 SGLDEGLMYEYRVYAENIAGIGKCSKSCEPVPARDPCD 19381
Score = 111 bits (278), Expect = 8e-24
Identities = 306/1510 (20%), Positives = 522/1510 (34%), Gaps = 241/1510 (15%)
Query: 758 EEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLI---LSTSQTTAPDAP 814
E GD + L + A V + P + +Y + + I + + P AP
Sbjct: 7131 ETGDRVKMKTLSAYAELV----ISPSERSDKGIYTLKLENRVKTISGEIDVNVIARPSAP 7186
Query: 815 PDPTVDQVDDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTLSDL 870
+ + S+ + W P +P+TGY + + T++ T T+ DL
Sbjct: 7187 KELKFGDITKDSVHLTWEPPDDDGGSPLTGYVVEKREVSRKTWTKVMDFVTDLEFTVPDL 7246
Query: 871 QPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP 930
G +Y + A + P + + + + P ++++ + T + + W PP
Sbjct: 7247 VQGKEYLFKVCARNKCGPGEPAYVDEPVNMSTPATVPDPPENVKWRDRTANSIFLTWDPP 7306
Query: 931 E----SAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRES 986
+ S + GY V+ P P++ T EVTGL G Y ++V A++ S
Sbjct: 7307 KNDGGSRIKGYIVERCPRGSDKWVACGEPVA-ETKMEVTGLEEGKWYAYRVKALNRQGAS 7365
Query: 987 KP---------------------------LTAQQTTKLDAPTNLQFVNETDSTVLVRWTP 1019
KP LT + TK++ P + E T WT
Sbjct: 7366 KPSRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKIT----WT- 7420
Query: 1020 PRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKAT 1079
+A + + +T P++ V SK Y + V + G +
Sbjct: 7421 -KADMI-LKQDKRITIENVPKKSTVTIVDSK-----RSDTGTYIIEAVNVCGRATAVVEV 7473
Query: 1080 GVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRI--GFKLGVRPSQGGEAPREVTSDSGS 1137
V +PG T+VT + ++TW P PR G K+ + EV S
Sbjct: 7474 NVLD--KPGPPAAFDITDVTNESCLLTWNP-PRDDGGSKITNYVVERRATDSEVWHKLSS 7530
Query: 1138 IV------VSGLTPGVEYVYTI---QVLRDGQERDA-PIVNKV-VTPLSPPTNLHLEANP 1186
V + L P EY++ + + G+ A PI K P PPT L ++
Sbjct: 7531 TVKDTNFKATKLIPNKEYIFRVAAENMYGVGEPVQASPITAKYQFDPPGPPTRLE-PSDI 7589
Query: 1187 DTGVLTVSW---ERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEY 1243
+T++W + ITGY + + + ++ D ++ L+ +Y
Sbjct: 7590 TKDAVTLTWCEPDDDGGSPITGYWVERLDPDTDKWVRCNKMPVKD-TTYRVKGLTNKKKY 7648
Query: 1244 NVSVYTV------KDDKESVP--ISDTIIPEVPQLTDLSFVDITDSSIGLRWTPL---NS 1292
V K K + P I D I P P + D+ +S+ L WT
Sbjct: 7649 RFRVLAENLAGPGKPSKSTEPILIKDPIDPPWPP-GKPTVKDVGKTSVRLNWTKPEHDGG 7707
Query: 1293 STIIGYRITVVAAG--------EGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLING 1344
+ I Y I ++ G EG+P + + + GL G +Y V +
Sbjct: 7708 AKIESYVIEMLKTGTDEWVRVAEGVPTTQ---------HLLPGLMEGQEYSFRVRAVNKA 7758
Query: 1345 GESAPT-----TLTQQTAVP--PPTDLRFTNIGPDTMRVTWAPPP---SIDLTNFLVRYS 1394
GES P+ L ++ P PP L NI +T + W P +TN++V
Sbjct: 7759 GESEPSEPSDPVLCREKLYPPSPPRWLEVINITKNTADLKWTVPEKDGGSPITNYIVEKR 7818
Query: 1395 PVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVS-------SVYEQHESTPLRGRQKT 1447
V+ + + + D +T L G+ YV V+ S Y + E + L T
Sbjct: 7819 DVR-RKGWQTVDTTVKDTKCTVTPLTEGSLYVFRVAAENAIGQSDYTEIEDSVLAKDTFT 7877
Query: 1448 GLDSPTGIDFSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRNS 1503
P + D+T + W P+ I Y I + + + +
Sbjct: 7878 TPGPPYALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKERLGTRWVKAGKTAGPDCN 7937
Query: 1504 ITLTNLTPGTEYVVSIVALN----GREESP---LLIGQQSTVSDVPRDLEVVAATPTSLL 1556
+T++ GTE + A N G P L I ++ P DL V A +
Sbjct: 7938 FRVTDVIEGTEVQFQVRAENEAGVGHPSEPTEILSIEDPTSPPSPPLDLHVTDAGRKHIA 7997
Query: 1557 ISWDAPAVTVRYYRITYGETGGNSPVQEFTVP----GSKSTATIS-------------GL 1599
I+W P E G SP+ + V G++ ++ G+
Sbjct: 7998 IAWKPP------------EKNGGSPIIGYHVEMCPVGTEKWMRVNSRPIKDLKFKVEEGV 8045
Query: 1600 KPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSP 1659
P +Y + V AV G S+P I+ P D++ + I V S
Sbjct: 8046 VPDKEYVLRVRAVNAIG----VSEPSEISENVVAKDPDCKPTIDLETHDIIVIEGEKLSI 8101
Query: 1660 VTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYA---------QNPSG 1710
+R P + D+ M + + +E SV A +N G
Sbjct: 8102 PVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLG 8161
Query: 1711 ESQPLVQTAVTNIDRP-KGLAFTDVDVDSIKIAWESPQ--GQVSRYRVTYSSPEDGIHEL 1767
+ + V + P K + +D+ S K+ WE P+ G E G
Sbjct: 8162 SATASINVKVIGLPGPCKDIKASDITKSSCKLTWEPPEFDGGTPILHYVLERREAGRRTY 8221
Query: 1768 FPAPDGEEDTA-ELQGLRPGSEYTVSVVALH-----DDME-SQPLIGTQSTAIP-APTDL 1819
P GE + ++ L P EY V A++ + +E P+I P P D+
Sbjct: 8222 IPVMSGENKLSWTVKDLIPNGEYFFRVKAVNKVGGGEYIELKNPVIAQDPKQPPDPPVDV 8281
Query: 1820 KFTQVTPTSLSAQWTPP----NVQLTGYRV-RVTPKEKTGPMKEINLAPDSSSVVVSGLM 1874
+ T +++ W PP ++ GY + ++ E+ +L P + GL
Sbjct: 8282 EVHNPTAEAMTITWKPPLYDGGSKIMGYIIEKIAKGEERWKRCNEHLVP-ILTYTAKGLE 8340
Query: 1875 VATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTI------------- 1921
+Y+ V A S P++ T + V P +V T +
Sbjct: 8341 EGKEYQFRVRAENAAGISEPSRATPPT-KAVDPIDAPKVILRTSLEVKRGDEIALDASIS 8399
Query: 1922 -----TISWRTKTETITGFQVD--------------------AVPANGQTPIQRTIKPDV 1956
TI+W I ++ +P + I + K +
Sbjct: 8400 GSPYPTITWIKDENVIVPEEIKKRAAPLVRRRKGEVQEEEPFVLPLTQRLSIDNSKKGES 8459
Query: 1957 RSYTITGLQPGTDYKIYLYTL-NDNA-RSSPVVIDASTAIDAPSNLRFLATTPNSLLVSW 2014
+ L+P D+ +Y+ + ND+ +P + P N F S+L W
Sbjct: 8460 QLRVRDSLRP--DHGLYMIKVENDHGIAKAPCTVSVLDTPGPPINFVFEDIRKTSVLCKW 8517
Query: 2015 QPP----RARITGYIIKYEKPGSPPRE-VVPRPRPGVTEATITGLEPGTEYTIYVIALKN 2069
+PP + I Y ++ + P E +V + ++T L G EY V A
Sbjct: 8518 EPPLDDGGSEIINYTLEKKDKTKPDSEWIVVTSTLRHCKYSVTKLIEGKEYLFRVRAENR 8577
Query: 2070 NQKSEPLIGR 2079
P + +
Sbjct: 8578 FGPGPPCVSK 8587
Score = 109 bits (273), Expect = 3e-23
Identities = 290/1404 (20%), Positives = 524/1404 (37%), Gaps = 190/1404 (13%)
Query: 812 DAPPDPT----VDQVDDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETAN 863
D P PT + + + S+ ++W P+ + +T Y ++ + TE++
Sbjct: 20263 DRPGPPTGPVVISDITEESVTLKWEPPKYDGGSQVTNYILLKRETSTAVWTEVSATVART 20322
Query: 864 SVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFV-EVTDVK 922
+ + L G +Y I A EN+ I T P P +V VT
Sbjct: 20323 MMKVMKLTTGEEYQFRIKA--ENRFGISDHIDSACVTVKLPYTTPGPPSTPWVTNVTRES 20380
Query: 923 VTIMWTPPES----AVTGYRVDVIPVN-LPGEHGQRLPISRNTFAEVTGLSPGVTYYFKV 977
+T+ W P S AV GY +++ N + + +L I R T +VT +S G+ Y F+V
Sbjct: 20381 ITVGWHEPVSNGGSAVVGYHLEMKDRNSILWQKANKLVI-RTTHFKVTTISAGLIYEFRV 20439
Query: 978 FAVSHGRESKPL-TAQQTTKLDA---PTNLQFVNETDSTVLVRWTPPR----AQITGYRL 1029
+A + KP ++ +DA P N++ + + ++V + W P ++ITGY
Sbjct: 20440 YAENAAGVGKPSHPSEPVLAIDACEPPRNVRITDISKNSVSLSWQQPAFDGGSKITGYI- 20498
Query: 1030 TVGLTRRGQP-----RQYNVGPSVSKYPLRNLQPASEYTVSLVA--IKGNQESP-KATGV 1081
+ RR P + + +++ + L S+Y + A G+ +P + G
Sbjct: 20499 ---VERRDLPDGRWTKASFTNVTETQFIISGLTQNSQYEFRVFARNAVGSISNPSEVVGP 20555
Query: 1082 FTTLQ----PGSSIPPYNTEVTE----TTIV----ITWTPAPRI-GFKLGVRPSQGGEAP 1128
T + P +P TEV + T++ I+ PAP I +K
Sbjct: 20556 ITCIDSYGGPVIDLPLEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVC 20615
Query: 1129 REVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDT 1188
E T+D SI++ Y +++ A I +++ PP
Sbjct: 20616 VENTTDLASILIKDADRLNSGCYELKLRNAMGSASATIRVQILDKPGPPGGPIEFKTVTA 20675
Query: 1189 GVLTVSWERSTTPD----ITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYN 1244
+T+ W R D IT Y + T+ + + E H ++ T + G EY
Sbjct: 20676 EKITLLW-RPPADDGGAKITHYIVEKRETSRVVWSMVSE--HLEECIITTTKIIKGNEYI 20732
Query: 1245 VSVYTVKDDKESVPI-SDTII----------PEVPQLTDLSFVDITDSSIGLRWT-PL-- 1290
V V P+ SD+++ P +P++T IT +S+ + W+ P+
Sbjct: 20733 FRVRAVNKYGIGEPLESDSVVAKNAFVTPGPPGIPEVT-----KITKNSMTVVWSRPIAD 20787
Query: 1291 NSSTIIGYRITVVAAGEGIPIFEDFVDSSVGYY------------TVTGLEPGIDYDISV 1338
S I GY E S+G++ VTGL DY V
Sbjct: 20788 GGSDISGY------------FLEKRDKKSLGWFKVLKETIRDTRQKVTGLTENSDYQYRV 20835
Query: 1339 ITLINGGE---SAPTTLTQQTAVP-----PPTDLRFTNIGPDTMRVTWAPP---PSIDLT 1387
+ G+ S P+ + A P PP +R + ++ + W+ P +T
Sbjct: 20836 CAVNAAGQGPFSEPSEF-YKAADPIDPPGPPAKIRIADSTKSSITLGWSKPVYDGGSAVT 20894
Query: 1388 NFLVRYSPVKNEE-DVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQ- 1445
++V + EE V++NL PG Y VS+V + P+ +
Sbjct: 20895 GYVVEIRQGEEEEWTTVSTKGEVRTTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEP 20954
Query: 1446 ---KTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRN 1502
K L++P ID S + ++ R P + ++ +R
Sbjct: 20955 VQAKDILEAPE-IDLDVALRTSVIAKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARY 21013
Query: 1503 SI---------TLTNLTPGT--EYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAAT 1551
SI T+ +T +Y+++I G +S + + + L+V +
Sbjct: 21014 SIENTDSSSLLTIPQVTRNDTGKYILTIENGVGEPKSSTVSVKVLDTPAACQKLQVKHVS 21073
Query: 1552 PTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGL-----KPGVDYT 1606
++ + WD P + I Y ++ + ++V K ++T L K +
Sbjct: 21074 RGTVTLLWDPPLIDGGSPIINYVIEKRDATKRTWSVVSHKCSSTSFKLIDLSEKTPFFFR 21133
Query: 1607 ITVYAVTGRGDSPASSKPISINYRTEIDKP-SQMQVTDVQDNSISVKW----LPSSSPVT 1661
+ G G+ +++P+ E+ P + + D S+ + W S +T
Sbjct: 21134 VLAENEIGIGEPCETTEPVK---AAEVPAPIRDLSMKDSTKTSVILSWTKPDFDGGSVIT 21190
Query: 1662 GYRVTTTPKNGPGPTKTKTAGPDQT-EMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAV 1720
Y V + G G AG +T E+ + L+ V+A+N G S P+ +
Sbjct: 21191 EYVV---ERKGKGEQTWSHAGISKTCEIEVSQLKEQSVLEFRVFAKNEKGLSDPVTIGPI 21247
Query: 1721 TNIDRPKGLAFT-DVDVDSIKIAWESPQ-GQVSRYRVTY-SSPEDGIHEL---FPAPDGE 1774
T K L T +VD+ I A + + G + Y P+ I L P + E
Sbjct: 21248 T----VKELIITPEVDLSDIPGAQVTVRIGHNVHLELPYKGKPKPSISWLKDGLPLKESE 21303
Query: 1775 -------EDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPT----DLKFTQ 1823
E+ L E+ + D+ + + + P+ ++F +
Sbjct: 21304 FVRFSKTENKITLSIKNAKKEHGGKYTVILDNAVCRIAVPITVITLGPPSKPKGPIRFDE 21363
Query: 1824 VTPTSLSAQWTPP----NVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKY 1879
+ S+ W P ++T Y + +T K + + ++ V L+ +Y
Sbjct: 21364 IKADSVILSWDVPEDNGGGEITCYSIEKRETSQTN-WKMVCSSVARTTFKVPNLVKDAEY 21422
Query: 1880 EVSVYALKDTLTSRPAQGVVTTLEN----VSPPRRARVTDATETTITISWRTKT----ET 1931
+ V A S+P + ++ PP + + + T ++++W
Sbjct: 21423 QFRVRAENRYGVSQPLVSSIIVAKHQFRIPGPPGKPVIYNVTSDGMSLTWDAPVYDGGSE 21482
Query: 1932 ITGFQVDAVPANGQTPIQRTIKP-DVRSYTITGLQPGTDYKIYLYTLNDNARSSP----V 1986
+TGF V+ N + P R Y TGL G DY+ +Y N SSP
Sbjct: 21483 VTGFHVEKKERNSILWQKVNTSPISGREYRATGLVEGLDYQFRVYAENSAGLSSPSDPSK 21542
Query: 1987 VIDASTAIDAPSNLRFLATTPNSLLVSWQPP----RARITGYIIKYEKPGSPPREVVPRP 2042
A + +D P ++ T ++ + W PP ++I GY I+ ++ G+
Sbjct: 21543 FTLAVSPVDPPGTPDYIDVTRETITLKWNPPLRDGGSKIVGYSIE-KRQGNERWVRCNFT 21601
Query: 2043 RPGVTEATITGLEPGTEYTIYVIA 2066
+ T+TGL PG Y +IA
Sbjct: 21602 DVSECQYTVTGLSPGDRYEFRIIA 21625
Score = 109 bits (272), Expect = 4e-23
Identities = 299/1423 (21%), Positives = 501/1423 (35%), Gaps = 243/1423 (17%)
Query: 728 VTEITASSFVVSW----VSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPG 783
+++I A + +SW ++ + VE GD L T TS + L+PG
Sbjct: 12696 ISDIDADACSLSWHIPLEDGGSNITNYIVEKCDVSRGDWVTAL-ASVTKTSCRVGKLIPG 12754
Query: 784 RKYIVNV-----YQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ--- 835
++YI V + ISE +++ P P + V +V+ I V W RP
Sbjct: 12755 QEYIFRVRAENRFGISEPLTSPKMVAQFPFGVPSEPKNARVTKVNKDCIFVAWDRPDSDG 12814
Query: 836 -APITGYRIVYSPS-----VEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQES 889
+PI GY I V+ + T + E + L G++Y+ IYA+ + S
Sbjct: 12815 GSPIIGYLIERKERNSLLWVKANDTLVRSTE----YPCAGLVEGLEYSFRIYALNKAGSS 12870
Query: 890 TPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPVN 945
P + T D P + ++VT V+++W P+ S + GY V+
Sbjct: 12871 PPSKPTEYVTARMPVDPPGKP---EVIDVTKSTVSLIWARPKHDGGSKIIGYFVEA--CK 12925
Query: 946 LPGEHGQRLPISRNTFAE----VTGLSPGVTYYFKVF---AVSHGRESKPLTAQQTTKLD 998
LPG+ R + + + TGL Y F+ AV+ S+P +
Sbjct: 12926 LPGDKWVRCNTAPHQIPQEEYTATGLEEKAQYQFRAIARTAVNISPPSEPSDPVTILAEN 12985
Query: 999 APTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQ----------YNVGPSV 1048
P + S + V+ G + + T G+P +
Sbjct: 12986 VPPRIDLSVAMKSLLTVK--------AGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGI 13037
Query: 1049 SKYPLRNL----------QPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEV 1098
RNL + + +YT++ G++ + V +PG PP + ++
Sbjct: 13038 KMAMQRNLCTLELFSVNRKDSGDYTITAENSSGSKSATIKLKVLD--KPG---PPASVKI 13092
Query: 1099 TE---TTIVITWTPAPRIG------FKLGVR-PSQGGEAPREVTSDSGSIVVSGLTPGVE 1148
+ +++W P G + + R S+ A T S V L G E
Sbjct: 13093 NKMYSDRAMLSWEPPLEDGGSEITNYIVDKRETSRPNWAQVSATVPITSCSVEKLIEGHE 13152
Query: 1149 YVYTIQVLRDGQERDAPIVNKVV--TPLSPPTNLH--LEANPDTGVLTVSWERSTT---P 1201
Y + I D + P PP + +N +TVSW+
Sbjct: 13153 YQFRICAENKYGVGDPVFTEPAIAKNPYDPPGRCDPPVISNITKDHMTVSWKPPADDGGS 13212
Query: 1202 DITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTV--------KDD 1253
ITGY + T + ++ + L G EY V + D
Sbjct: 13213 PITGYLLEKRETQAVNWTKVNRKPIIER-TLKATGLQEGTEYEFRVTAINKAGPGKPSDA 13271
Query: 1254 KESVPISDTIIPEVPQLTDLSFVDITDSSIGLRWTPL---NSSTIIGYRITVVAAGEGIP 1310
++ D P P + D T SS+ L W S IIGY + V A
Sbjct: 13272 SKAAYARDPQYPPGPPAFPKVY-DTTRSSVSLSWGKPAYDGGSPIIGYLVEVKRADS--- 13327
Query: 1311 IFEDFVDSSVGY------YTVTGLEPGIDYDISVITLINGGESAPTTL-----TQQTAVP 1359
+++V ++ + VTGL Y V + G S P+ + + +P
Sbjct: 13328 --DNWVRCNLPQNLQKTRFEVTGLMEDTQYQFRVYAVNKIGYSDPSDVPDKHYPKDILIP 13385
Query: 1360 P----PTDLRFTNI--GPDTMR----VTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISP 1409
P DLR T I TMR V PPP I + P N D L I
Sbjct: 13386 PEGELDADLRKTLILRAGVTMRLYVPVKGRPPPKITWS------KPNVNLRDRIGLDIKS 13439
Query: 1410 SDNAVVL----TNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSF 1465
+D L N +Y++++ + + E T + T P + +I+ +S
Sbjct: 13440 TDFDTFLRCENVNKYDAGKYILTLENSCGKKEYTIVVKVLDTP-GPPVNVTVKEISKDSA 13498
Query: 1466 TVHWIAP----RATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVA 1521
V W P + I Y ++ S+ S + NL G Y + A
Sbjct: 13499 YVTWEPPIIDGGSPIINYVVQKRDAERKSWSTV-TTECSKTSFRVANLEEGKSYFFRVFA 13557
Query: 1522 LNGREESPLLIGQQSTVSDVPR---------DLEVVAATPTSLLISWDAPAVTVRYYRIT 1572
E+ IG D + DL+V + + +S I W P I
Sbjct: 13558 -----ENEYGIGDPGETRDAVKASQTPGPVVDLKVRSVSKSSCSIGWKKPHSDGGSRIIG 13612
Query: 1573 YGETGGNSPVQEFTVPGSKSTATISGLK---------PGVDYTITVYAVTGRGDSPASSK 1623
Y V +F +K + L G +YT V A G+ S
Sbjct: 13613 Y--------VVDFLTEENKWQRVMKSLSLQYSAKDLTEGKEYTFRVSAENENGEGTPSE- 13663
Query: 1624 PISINYRTEIDKPSQMQVTDVQDNSISVKWLPS----SSPVTGYRVTTTPKNGPGPTKTK 1679
I++ R ++ P + +K LP + + +R+ K P P+ +
Sbjct: 13664 -ITVVARDDVVAP-----------DLDLKGLPDLCYLAKENSNFRLKIPIKGKPAPSVSW 13711
Query: 1680 TAGPD----QTEMTIEGLQPTVEYVV-----------SVYAQNPSGESQPLVQTAVTNID 1724
G D T +++E +V ++ +N +G + + V
Sbjct: 13712 KKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKEGTISIKVVGKP 13771
Query: 1725 R-PKG-LAFTDVDVDSIKIAWESPQGQVSRYRVTY-SSPEDGIHELFP--APDGEEDTAE 1779
P G + F +V +++ + W P+ Y D ++ + A ++ T
Sbjct: 13772 GIPTGPIKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDSVNNKWVTCASAVQKTTFR 13831
Query: 1780 LQGLRPGSEYTVSVVA-----LHDDMESQPLIGTQSTAIP-APTDLKFTQVTPTSLSAQW 1833
+ L G EYT V A + + ++S+P++ +P AP V S+S W
Sbjct: 13832 VTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVPDAPPPPNIVDVRHDSVSLTW 13891
Query: 1834 TPP----NVQLTGYRVRVTPKEKTGPM-KEINLAP-DSSSVVVSGLMVATKYEVSVYAL- 1886
T P +TGY + KE+ + K N P V+GL +YE V A+
Sbjct: 13892 TDPKKTGGSPITGYHLEF--KERNSLLWKRANKTPIRMRDFKVTGLTEGLEYEFRVMAIN 13949
Query: 1887 -----KDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKT----ETITGFQV 1937
K +L S P V L+ + PP + V + T ++T+ W +TG+ V
Sbjct: 13950 LAGVGKPSLPSEP----VVALDPIDPPGKPEVINITRNSVTLIWTEPKYDGGHKLTGYIV 14005
Query: 1938 DA--VPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLN 1978
+ +P+ P+ ++T+T L G Y+ + N
Sbjct: 14006 EKRDLPSKSWMKANHVNVPEC-AFTVTDLVEGGKYEFRIRAKN 14047
Score = 108 bits (269), Expect = 9e-23
Identities = 265/1341 (19%), Positives = 468/1341 (34%), Gaps = 163/1341 (12%)
Query: 780 LLPGRKYIVNVYQISEDGE----QSLILSTSQTTAPDAPPD-PTVDQVDDTSIVVRWSRP 834
L+ G +YI V ++ G+ QS + P PP+ P V V + V W RP
Sbjct: 14231 LIQGNEYIFRVSAVNHYGKGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSWKRP 14290
Query: 835 Q----APITGYRIVYSPSVEGSSTE-LNLPETANSVTLSDLQPGVQYNITIYA-----VE 884
+ ITGY + + P + ++ LQ G Y + A +
Sbjct: 14291 VDDGGSEITGYHVERREKKSLRWVRAIKTPVSDLRCKVTGLQEGSTYEFRVSAENRAGIG 14350
Query: 885 ENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPES----AVTGYRVD 940
E++ V+ ++ P + P D T ++ W P +TGY V+
Sbjct: 14351 PPSEASDSVLMKDAAYPPGPPSNPHVTD-----TTKKSASLAWGKPHYDGGLEITGYVVE 14405
Query: 941 VIPVN----LPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQ--QT 994
V + G L I++ V L Y F++ A++ +P +
Sbjct: 14406 HQKVGDEAWIKDTTGTALRITQFV---VPDLQTKEKYNFRISAINDAGVGEPAVIPDVEI 14462
Query: 995 TKLDAPTNLQFVNETDSTVLVR-------WTP----PRAQITGYRLTVGLTRRGQPRQYN 1043
+ + + + E T++VR + P P ++T + + L R
Sbjct: 14463 VEREMAPDFELDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKNRANIENTE 14522
Query: 1044 VGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTI 1103
++ P N ++ +++ G + V T P ++ P T++T+ ++
Sbjct: 14523 -SFTLLIIPECNRYDTGKFVMTIENPAGKKSGFVNVRVLDTPGPVLNLRP--TDITKDSV 14579
Query: 1104 VITWT-PAPRIGFKLGVRPSQGGEAPREVTSDSGS------IVVSGLTPGVEYVYTIQVL 1156
+ W P G ++ + EA R+ S + + V+GL+ G EY + +
Sbjct: 14580 TLHWDLPLIDGGSRITNYIVEKREATRKSYSTATTKCHKCTYKVTGLSEGCEYFFRVMAE 14639
Query: 1157 RD---GQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPD---ITGYRITT 1210
+ G+ + K SPP +L++ + ++++W + ITGY I
Sbjct: 14640 NEYGIGEPTETTEPVKASEAPSPPDSLNI-MDITKSTVSLAWPKPKHDGGSKITGYVIEA 14698
Query: 1211 TPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISD--TIIPEVP 1268
Q + V + C NL+ G EY V V S P I+ E
Sbjct: 14699 QRKGSDQWTHITTVKGLE---CVVRNLTEGEEYTFQVMAVNSAGRSAPRESRPVIVKEQT 14755
Query: 1269 QLTDLSFVDITDSSIGLRWTPLNSSTI--IGYRITVVAAGEGIPI--------FEDFVDS 1318
L +L I + + I +G V +G I FE S
Sbjct: 14756 MLPELDLRGIYQKLVIAKAGDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATS 14815
Query: 1319 SVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTW 1378
++ Y ++ ++ T PP ++F + D + +W
Sbjct: 14816 TILNINECVRSDSGPYPLTARNIVGEVGDVITIQVHDIPGPPTGPIKFDEVSSDFVTFSW 14875
Query: 1379 APPPS---IDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSS---- 1431
PP + + ++N++V + V EL+ + T L G EY V +
Sbjct: 14876 DPPENDGGVPISNYVVEMRQTDSTTWV-ELATTVIRTTYKATRLTTGLEYQFRVKAQNRY 14934
Query: 1432 -VYEQHESTPLRGRQKTGLDSPTGI-DFSDITANSFTVHWIAP----RATITGYRIRHHP 1485
V S + + P G + +T +S T+ W P + I GY +
Sbjct: 14935 GVGPGITSACIVANYPFKVPGPPGTPQVTAVTKDSMTISWHEPLSDGGSPILGYHVERKE 14994
Query: 1486 EHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN-------GREESPLLIGQQSTV 1538
+ + N + LT G Y ++A N + P+L
Sbjct: 14995 RNGILWQTVSKALVPGNIFKSSGLTDGIAYEFRVIAENMAGKSKPSKPSEPMLALDPIDP 15054
Query: 1539 SDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPG----SKSTA 1594
P L + T T + W P T + +Y + P + ++
Sbjct: 15055 PGKPVPLNITRHTVT---LKWAKPEYTGGFKITSYIVEKRDLPNGRWLKANFSNILENEF 15111
Query: 1595 TISGLKPGVDYTITVYAVTGRGD-SPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKW 1653
T+SGL Y V A G SP S +I R +++ P +D I
Sbjct: 15112 TVSGLTEDAAYEFRVIAKNAAGAISPPSEPSDAITCRDDVEAPKIKVDVKFKDTVI---- 15167
Query: 1654 LPSSSPVTGYRVTTTPKNGPGPTK------TKTAGPDQTEMTIEGLQPTV---------E 1698
+R+ P PT + G + E+ I +
Sbjct: 15168 ---LKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDS 15224
Query: 1699 YVVSVYAQNPSGESQPLVQTAVTNIDRP----KGLAFTDVDVDSIKIAWESP---QGQVS 1751
++ A NP G ++ + V +DRP LA T+V + ++W P G
Sbjct: 15225 GAYTLTATNPGGFAKHIFNVKV--LDRPGPPEGPLAVTEVTSEKCVLSWFPPLDDGGAKI 15282
Query: 1752 RYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALH-----DDMESQPLI 1806
+ + + A + + ++ L G+EY V+A++ + +ES+P++
Sbjct: 15283 DHYIVQKRETSRLAWTNVASEVQVTKLKVTKLLKGNEYIFRVMAVNKYGVGEPLESEPVL 15342
Query: 1807 GTQSTAIP-APTDLKFTQVTPTSLSAQWTPPN----VQLTGYRVRVTPKEKTGPMKEINL 1861
P P + + T +T S+ W P+ ++ Y V K +K
Sbjct: 15343 AVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEIINYIVERRDKAGQRWIKCNKK 15402
Query: 1862 APDSSSVVVSGLMVATKYEVSVYA-----LKDTLTSRPAQGVVTTLENVSPPRRARVTDA 1916
VSGL +YE + A + + P T+ PP RV D
Sbjct: 15403 TLTDLRYKVSGLTEGHEYEFRIMAENAAGISAPSPTSPFYKACDTVFKPGPPGNPRVLDT 15462
Query: 1917 TETTITISWRTKT----ETITGFQVD-AVPANGQTPIQRTIKP----DVRSYTITGLQPG 1967
+ ++I+I+W ITG+ V+ A+P + I + P SYTITGL
Sbjct: 15463 SRSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQI---VTPPAGLKATSYTITGLTEN 15519
Query: 1968 TDYKIYLYTLNDNARSSPVVI 1988
+YKI +Y +N P ++
Sbjct: 15520 QEYKIRIYAMNSEGLGEPALV 15540
Score = 106 bits (265), Expect = 2e-22
Identities = 320/1538 (20%), Positives = 543/1538 (35%), Gaps = 226/1538 (14%)
Query: 702 TSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSW----VSASDTVSGFRVEYELS 757
T P S V +T P VT+++ V W +++G+ +E
Sbjct: 12073 TGPPTESKPVIAKTKYDKPGRPDPPEVTKVSKEEMTVVWNPPEYDGGKSITGYFLE---K 12129
Query: 758 EEGDEPQYLDLPSTATS---VNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDA- 813
+E +++ + +A + + +LLP +Y V +E G L + A D
Sbjct: 12130 KEKHSTRWVPVNKSAIPERRMKVQNLLPDHEYQFRVKAENEIGIGEPSLPSRPVVAKDPI 12189
Query: 814 --PPDPTVDQVDDT---SIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANS 864
P PT +V DT SI + W +P API GY + P + +S + +
Sbjct: 12190 EPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAPIIGYVVEMRPKIADASPDEGWKRCNAA 12249
Query: 865 VTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGT------------------PRSDT 906
L V+ T+ +++ENQE V Q G P D
Sbjct: 12250 AQL------VRKEFTVTSLDENQEYEFRVCAQNQVGIGRPAELKEAIKPKEILEPPEIDL 12303
Query: 907 VPSPRDLQFVEV-TDVKV-TIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEV 964
S R L V +++ I+ P VT +V + V GQ + F +
Sbjct: 12304 DASMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVV---RKGQVDLVDTMAFLVI 12360
Query: 965 TGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAP-TNLQFVNETDSTVLVRWTPPR-- 1021
+ + + + V+ E + P ++L+ + T ++ V W PP
Sbjct: 12361 PNSTRDDSGKYSLTLVNPAGEKAVFVNVRVLDTPGPVSDLKVSDVTKTSCHVSWAPPEND 12420
Query: 1022 --AQITGYRLTVGLTRRGQPRQYNVGPSVSK--YPLRNLQPASEYTVSLVAIKGNQESPK 1077
+Q+T Y V + V P V K + + NL P +EY + A+ N+ P
Sbjct: 12421 GGSQVTHY--IVEKREADRKTWSTVTPEVKKTSFHVTNLVPGNEYYFRVTAV--NEYGPG 12476
Query: 1078 ATG-----VFTTLQPGSSIPPYNTEVTETT---IVITWTPAPRIG-FKLG--VRPSQGGE 1126
V + PP EVTE T + W P R G K+ + + E
Sbjct: 12477 VPTDVPKPVLASDPLSEPDPPRKLEVTEMTKNSATLAWLPPLRDGGAKIDGYITSYREEE 12536
Query: 1127 APREVTSDSG-----SIVVSGLTPGVEYVYTI---QVLRDGQERDAPIVNKVVTPLSPPT 1178
P + ++ S+VV+GL G +Y + + + R+A V + L PP
Sbjct: 12537 QPADRWTEYSVVKDLSLVVTGLKEGKKYKFRVAARNAVGVSLPREAEGVYEAKEQLLPPK 12596
Query: 1179 NL-----------------HLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSL 1221
L H+ P T W++ +T + + +
Sbjct: 12597 ILMPEQITIKAGKKLRIEAHVYGKPHP---TCKWKKGEDEVVTSSHLAVHKADSSSILII 12653
Query: 1222 EEVVHADQS--SCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPEVPQLTDLSFVDIT 1279
++V D S T +N S K V + D P P D+S DI
Sbjct: 12654 KDVTRKDSGYYSLTAENSSG----------TDTQKIKVVVMDAPGPPQPPF-DIS--DID 12700
Query: 1280 DSSIGLRW-TPLNS--STIIGYRITV--VAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDY 1334
+ L W PL S I Y + V+ G+ + +S V L PG +Y
Sbjct: 12701 ADACSLSWHIPLEDGGSNITNYIVEKCDVSRGDWVTALASVTKTSC---RVGKLIPGQEY 12757
Query: 1335 DISVITLINGGESAPTTLTQQTAVPP------PTDLRFTNIGPDTMRVTWAPPPSIDLTN 1388
V G S P T + A P P + R T + D + V W P S D +
Sbjct: 12758 IFRVRAENRFGISEPLTSPKMVAQFPFGVPSEPKNARVTKVNKDCIFVAWDRPDS-DGGS 12816
Query: 1389 FLVRYSPVKNEEDVAELSISPSDNAVVLTN-----LLPGTEYVVSVSSVYEQHESTPLRG 1443
++ Y ++ +E + L + +D V T L+ G EY + ++ + S P +
Sbjct: 12817 PIIGYL-IERKERNSLLWVKANDTLVRSTEYPCAGLVEGLEYSFRIYALNKAGSSPPSKP 12875
Query: 1444 RQ----KTGLDSPTGIDFSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPRED 1495
+ + +D P + D+T ++ ++ W P+ + I GY + R +
Sbjct: 12876 TEYVTARMPVDPPGKPEVIDVTKSTVSLIWARPKHDGGSKIIGYFVEACKLPGDKWVRCN 12935
Query: 1496 RVPHS--RNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTV---SDVPRDLEVVAA 1550
PH + T T L +Y +A SP +VP +++ A
Sbjct: 12936 TAPHQIPQEEYTATGLEEKAQYQFRAIARTAVNISPPSEPSDPVTILAENVPPRIDLSVA 12995
Query: 1551 TPTSLLIS------WDAPAVTVRYYRITYGETGGN-SPVQEFTVPGSKSTATIS----GL 1599
+ L + DA +++ + G P + + ++ T+
Sbjct: 12996 MKSLLTVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNR 13055
Query: 1600 KPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLP---- 1655
K DYTIT S + S I + + P+ +++ + + + W P
Sbjct: 13056 KDSGDYTITA-----ENSSGSKSATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLED 13110
Query: 1656 SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPL 1715
S +T Y V + P + P T ++E L EY + A+N G P+
Sbjct: 13111 GGSEITNYIVDKRETSRPNWAQVSATVPI-TSCSVEKLIEGHEYQFRICAENKYGVGDPV 13169
Query: 1716 -VQTAVT-NIDRPKGLA----FTDVDVDSIKIAWESPQGQ----VSRYRVTYSSPEDGIH 1765
+ A+ N P G +++ D + ++W+ P ++ Y + +
Sbjct: 13170 FTEPAIAKNPYDPPGRCDPPVISNITKDHMTVSWKPPADDGGSPITGYLLEKRETQAVNW 13229
Query: 1766 ELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAI------PAPTDL 1819
E T + GL+ G+EY V A++ +P +++ P P
Sbjct: 13230 TKVNRKPIIERTLKATGLQEGTEYEFRVTAINKAGPGKPSDASKAAYARDPQYPPGPPAF 13289
Query: 1820 -KFTQVTPTSLSAQWTPPNVQ----LTGYRVRVTPKEKTGPMKEINLAPD--SSSVVVSG 1872
K T +S+S W P + GY V V + ++ NL + + V+G
Sbjct: 13290 PKVYDTTRSSVSLSWGKPAYDGGSPIIGYLVEVKRADSDNWVR-CNLPQNLQKTRFEVTG 13348
Query: 1873 LMVATKYEVSVYALKDTLTSRPAQ--GVVTTLENVSPPRRARVTDATETTITISWRTKTE 1930
LM T+Y+ VYA+ S P+ + + PP D +T I + T
Sbjct: 13349 LMEDTQYQFRVYAVNKIGYSDPSDVPDKHYPKDILIPPEGELDADLRKTLILRAGVTMRL 13408
Query: 1931 TITGFQVDAVPANGQTPIQRT-IKPDVRSYTITGLQ-PGTDYKIYLYTLNDN-------- 1980
VP G+ P + T KP+V GL TD+ +L N N
Sbjct: 13409 --------YVPVKGRPPPKITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKYI 13460
Query: 1981 --------ARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPP----RARITGYIIKY 2028
+ +V+ P N+ + +S V+W+PP + I Y+++
Sbjct: 13461 LTLENSCGKKEYTIVVKVLDTPGPPVNVTVKEISKDSAYVTWEPPIIDGGSPIINYVVQK 13520
Query: 2029 EKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIA 2066
V T + LE G Y V A
Sbjct: 13521 RDAERKSWSTV-TTECSKTSFRVANLEEGKSYFFRVFA 13557
Score = 102 bits (255), Expect = 4e-21
Identities = 274/1373 (19%), Positives = 474/1373 (34%), Gaps = 187/1373 (13%)
Query: 766 LDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDT 825
+DL T + IP+ ++ ++ GE+++ ++ P D V V T
Sbjct: 12349 VDLVDTMAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFVNVRVLDTPGPVSDLKVSDVTKT 12408
Query: 826 SIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETAN-SVTLSDLQPGVQYNITI 880
S V W+ P+ + +T Y IV + + PE S +++L PG +Y +
Sbjct: 12409 SCHVSWAPPENDGGSQVTHY-IVEKREADRKTWSTVTPEVKKTSFHVTNLVPGNEYYFRV 12467
Query: 881 YAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTG 936
AV E P + + + PR L+ E+T T+ W PP + + G
Sbjct: 12468 TAVNEYGPGVPTDVPKPVLASDPLSEPDPPRKLEVTEMTKNSATLAWLPPLRDGGAKIDG 12527
Query: 937 YRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTK 996
Y P + + ++ VTGL G Y F+V A+
Sbjct: 12528 YITSYREEEQPADRWTEYSVVKDLSLVVTGLKEGKKYKFRV------------AARNAVG 12575
Query: 997 LDAPTNLQFVNETDSTVLVRWTPPR----AQIT---GYRLTVGLTRRGQPR--------- 1040
+ P + V E +L PP+ QIT G +L + G+P
Sbjct: 12576 VSLPREAEGVYEAKEQLL----PPKILMPEQITIKAGKKLRIEAHVYGKPHPTCKWKKGE 12631
Query: 1041 ---------QYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSI 1091
+ S S ++++ SL A + + V PG
Sbjct: 12632 DEVVTSSHLAVHKADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPGPPQ 12691
Query: 1092 PPYN-TEVTETTIVITW-TPAPRIGFKL------GVRPSQGGEAPREVTSDSGSIVVSGL 1143
PP++ +++ ++W P G + S+G + S V L
Sbjct: 12692 PPFDISDIDADACSLSWHIPLEDGGSNITNYIVEKCDVSRGDWVTALASVTKTSCRVGKL 12751
Query: 1144 TPGVEYVYTIQVLRDGQERDAPIVNKVV------TPLSPPTNLHLEANPDTGVLTVSWER 1197
PG EY++ ++ + K+V P P + N D + V+W+R
Sbjct: 12752 IPGQEYIFRVRAENRFGISEPLTSPKMVAQFPFGVPSEPKNARVTKVNKD--CIFVAWDR 12809
Query: 1198 STT---PDITGYRITTTPTNGQQG-NSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDD 1253
+ I GY I N + + +V + + C L GLEY+ +Y +
Sbjct: 12810 PDSDGGSPIIGYLIERKERNSLLWVKANDTLVRSTEYPCA--GLVEGLEYSFRIYALNKA 12867
Query: 1254 KESVPISDTIIPEVPQLTD----LSFVDITDSSIGLRWTPL---NSSTIIGYRITVV--- 1303
S P T D +D+T S++ L W S IIGY +
Sbjct: 12868 GSSPPSKPTEYVTARMPVDPPGKPEVIDVTKSTVSLIWARPKHDGGSKIIGYFVEACKLP 12927
Query: 1304 --------AAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVI--TLIN----GGESAP 1349
A IP E YT TGLE Y I T +N S P
Sbjct: 12928 GDKWVRCNTAPHQIPQEE---------YTATGLEEKAQYQFRAIARTAVNISPPSEPSDP 12978
Query: 1350 TTLTQQTAVPPPTDLRF-----------TNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKN 1398
T+ + VPP DL TN+ D V P P++ P +
Sbjct: 12979 VTILAEN-VPPRIDLSVAMKSLLTVKAGTNVCLDA-TVFGKPMPTVSWKKDGTLLKPAEG 13036
Query: 1399 EEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHEST-PLRGRQKTGLDSPTGIDF 1457
+ + ++ + + N +Y ++ + +T L+ K G P +
Sbjct: 13037 IKMAMQRNLCTLE--LFSVNRKDSGDYTITAENSSGSKSATIKLKVLDKPG--PPASVKI 13092
Query: 1458 SDITANSFTVHWIAP----RATITGYRIRHHPEHFSGRPREDRVPHS--RNSITLTNLTP 1511
+ + ++ + W P + IT Y + + + RP +V + S ++ L
Sbjct: 13093 NKMYSDRAMLSWEPPLEDGGSEITNYIV---DKRETSRPNWAQVSATVPITSCSVEKLIE 13149
Query: 1512 GTEYVVSIVALNGREESPLLIGQQSTVS---DVPR--DLEVVA-ATPTSLLISWDAPA-- 1563
G EY I A N + + + D P D V++ T + +SW PA
Sbjct: 13150 GHEYQFRICAENKYGVGDPVFTEPAIAKNPYDPPGRCDPPVISNITKDHMTVSWKPPADD 13209
Query: 1564 --VTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRG---DS 1618
+ Y + ET + + P + T +GL+ G +Y V A+ G S
Sbjct: 13210 GGSPITGYLLEKRETQAVNWTKVNRKPIIERTLKATGLQEGTEYEFRVTAINKAGPGKPS 13269
Query: 1619 PASSKPISINYRTEIDKPSQMQVTDVQDNSISVKW----LPSSSPVTGYRVTTTPKNGPG 1674
AS + + + P+ +V D +S+S+ W SP+ GY V +
Sbjct: 13270 DASKAAYARDPQYPPGPPAFPKVYDTTRSSVSLSWGKPAYDGGSPIIGYLVEVKRADSDN 13329
Query: 1675 PTKTK-TAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFT- 1732
+ +T + GL +Y VYA N G S P + V + PK +
Sbjct: 13330 WVRCNLPQNLQKTRFEVTGLMEDTQYQFRVYAVNKIGYSDP---SDVPDKHYPKDILIPP 13386
Query: 1733 --DVDVDSIKIAWESPQGQVSRY---------RVTYSSPEDGIHELFPAPDGEED----- 1776
++D D K + Y ++T+S P + + D
Sbjct: 13387 EGELDADLRKTLILRAGVTMRLYVPVKGRPPPKITWSKPNVNLRDRIGLDIKSTDFDTFL 13446
Query: 1777 TAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPP 1836
E +Y +++ E ++ T P P ++ +++ S W PP
Sbjct: 13447 RCENVNKYDAGKYILTLENSCGKKEYTIVVKVLDTPGP-PVNVTVKEISKDSAYVTWEPP 13505
Query: 1837 NVQ----LTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTS 1892
+ + Y V+ E+ + +S V+ L Y V+A +
Sbjct: 13506 IIDGGSPIINYVVQKRDAERKS-WSTVTTECSKTSFRVANLEEGKSYFFRVFAENEYGIG 13564
Query: 1893 RPAQ--GVVTTLENVSPPRRARVTDATETTITISWRTK----TETITGFQVDAVPANGQT 1946
P + V + P +V ++++ +I W+ I G+ VD + +
Sbjct: 13565 DPGETRDAVKASQTPGPVVDLKVRSVSKSSCSIGWKKPHSDGGSRIIGYVVDFLTEENKW 13624
Query: 1947 PIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSP--VVIDASTAIDAP 1997
QR +K Y+ L G +Y + N+N +P + + A + AP
Sbjct: 13625 --QRVMKSLSLQYSAKDLTEGKEYTFRVSAENENGEGTPSEITVVARDDVVAP 13675
Score = 102 bits (255), Expect = 4e-21
Identities = 306/1554 (19%), Positives = 528/1554 (33%), Gaps = 201/1554 (12%)
Query: 610 GPVEVFITETPSQPNSHPIQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSY 666
GP E + T + WN P ++IS YI+ R + + W + + +Y
Sbjct: 18498 GPPEGPLKVTGVTAEKCYLAWNPPLQDGGANISHYIIEKRETSRLS-WTQVSTEVQALNY 18556
Query: 667 TIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSE 726
+ L PG Y +++++ +YG E P+ S VT P ++
Sbjct: 18557 KVTKLLPGNEYIFRVMAVNKYGIGE-------------PLESGPVTACNPYKPPGPPSTP 18603
Query: 727 SVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDE-----PQYLDLPSTATSVNIPDLL 781
V+ IT S VV+W D G +E + E+ D+ + T + + L
Sbjct: 18604 EVSAITKDSMVVTWARPVDD-GGTEIEGYILEKRDKEGVRWTKCNKKTLTDLRLRVTGLT 18662
Query: 782 PGRKY-----IVNVYQISEDGEQSLILSTSQTTAPDAPP-DPTVDQVDDTSIVVRWSRP- 834
G Y N + E E S+ P PP +P V +S+ + WS+P
Sbjct: 18663 EGHSYEFRVAAENAAGVGEPSEPSVFYRACDALYPPGPPSNPKVTDTSRSSVSLAWSKPI 18722
Query: 835 ---QAPITGYRIVYSPSVEGSSTELNLPE--TANSVTLSDLQPGVQYNITIYAVEENQES 889
AP+ GY + + T P T++ L+ +YN I A+
Sbjct: 18723 YDGGAPVKGYVVEVKEAAADEWTTCTPPTGLQGKQFTVTKLKENTEYNFRICAINSEGVG 18782
Query: 890 TPVVIQQETTGTPRSD--TVPSPRDLQFVEVTDVKVTI-----MWTPPESAVTGYRVDVI 942
P + R + + DL+ V V T+ + PE V + + I
Sbjct: 18783 EPATLPGSVVAQERIEPPEIELDADLRKVVVLRASATLRLFVTIKGRPEPEVKWEKAEGI 18842
Query: 943 PVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTN 1002
+ + + VT G Y + G ++ + + AP N
Sbjct: 18843 LTD-RAQIEVTSSFTMLVIDNVTRFDSG--RYNLTLENNSGSKTAFVNVRVLDSPSAPVN 18899
Query: 1003 LQFVNETDSTVLVRWTPP----RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQP 1058
L +V + W PP A+IT Y + T R + + + + NLQ
Sbjct: 18900 LTIREVKKDSVTLSWEPPLIDGGAKITNYIVEKRETTRKAYATITNNCTKTTFRIENLQE 18959
Query: 1059 ASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYN------TEVTETTIVITW-TPAP 1111
Y ++A + E TT S PP +VT T I W P
Sbjct: 18960 GCSYYFRVLA---SNEYGIGLPAETTEPVKVSEPPLPPGRVTLVDVTRNTATIKWEKPES 19016
Query: 1112 RIGFKLG----VRPSQGGEAPREVTS-DSGSIVVSGLTPGVEYVYTIQVLR-----DGQE 1161
G K+ ++G E T + +SGLT G EYV+ + + D ++
Sbjct: 19017 DGGSKITGYVVEMQTKGSEKWSTCTQVKTLEATISGLTAGEEYVFRVAAVNEKGRSDPRQ 19076
Query: 1162 RDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDIT-GYRITTTPTNGQQGNS 1220
P++ + + + P L V D+ R T + G +
Sbjct: 19077 LGVPVIARDI-EIKPSVELPFH------TFNVKAREQLKIDVPFKGRPQATVNWRKDGQT 19129
Query: 1221 LEEVVHADQSS---CTFDNLSPGLEYNVSVY--TVKDDKESVPISDTII------PEVPQ 1269
L+E + SS T ++ + +V Y V + S+ + TII P P
Sbjct: 19130 LKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSNSAGSITVPITIIVLDRPGPPGPI 19189
Query: 1270 LTDLSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIFEDFVDSSVGYYT--VTG 1327
D +++ SI + W P +V E V +V + +
Sbjct: 19190 RID----EVSCDSITISWNPPEYDGGCQISNYIVEKKETTSTTWHIVSQAVARTSIKIVR 19245
Query: 1328 LEPGIDYDISVITLINGGESAPTTLTQQTA------VPPPTDLRFTNIGPDTMRVTWAPP 1381
L G +Y V G+S+ + + A PP + + TM VTW P
Sbjct: 19246 LTTGSEYQFRVCAENRYGKSSYSESSAVVAEYPFSPPGPPGTPKVVHATKSTMLVTWQVP 19305
Query: 1382 PSIDLTNFLVRYSPVKNEEDV---AELSISPSDNAVVLTNLLPGTEY--------VVSVS 1430
+ + + + K + I +D + ++ L G Y + +
Sbjct: 19306 VNDGGSRVIGYHLEYKERSSILWSKANKILIADTQMKVSGLDEGLMYEYRVYAENIAGIG 19365
Query: 1431 SVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPR----ATITGYRIRHHPE 1486
+ E P R D P + ++IT S ++ W P A ITGY + E
Sbjct: 19366 KCSKSCEPVPAR----DPCDPPGQPEVTNITRKSVSLKWSKPHYDGGAKITGYIVERR-E 19420
Query: 1487 HFSGRPREDRVPHSRNS-ITLTNLTPGTEYVVSIVALNGREE--------SPLLIGQQST 1537
GR + + + + +T LT Y + A N + P+++
Sbjct: 19421 LPDGRWLKCNYTNIQETYFEVTELTEDQRYEFRVFARNAADSVSEPSESTGPIIVKDDVE 19480
Query: 1538 VSDVPRDLE----VVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKST 1593
V D++ +V L I+ D + I++ + G + T S
Sbjct: 19481 PPRVMMDVKFRDVIVVKAGEVLKINADIAGRPLPV--ISWAKDGIEIEERARTEIISTDN 19538
Query: 1594 ATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKP----SQMQVTDVQDNSI 1649
T+ +K + Y +T + + A ++ +++N + +DKP +++ +
Sbjct: 19539 HTLLTVKDCIRRDTGQYVLTLK--NVAGTRSVAVNCKV-LDKPGPPAGPLEINGLTAEKC 19595
Query: 1650 SVKW---LPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQ 1706
S+ W Y + + T + L EY+ V
Sbjct: 19596 SLSWGRPQEDGGADIDYYIVEKRETSHLAWTICEGELQMTSCKVTKLLKGNEYIFRVTGV 19655
Query: 1707 NPSGESQPLVQTAVTNID------RPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSP 1760
N G +PL A+ +D P L T V +S+ + W P+ Y
Sbjct: 19656 NKYGVGEPLESVAIKALDPFTVPSPPTSLEITSVTKESMTLCWSRPESDGGSEISGYIIE 19715
Query: 1761 EDGIHELFPAPDGEEDTAELQ----GLRPGSEYTVSVVA-----LHDDMESQPLIGTQST 1811
+ L ++ +L+ GLR G EY V A L E+ PLI +
Sbjct: 19716 RREKNSLRWVRVNKKPVYDLRVKSTGLREGCEYEYRVYAENAAGLSLPSETSPLIRAEDP 19775
Query: 1812 A-IPA-PTDLKFTQVTPTSLSAQWTPP----NVQLTGYRVRVTPKEKTGPMKEINLAPDS 1865
+P+ P+ K T+++ W P +TGY V + T I +
Sbjct: 19776 VFLPSPPSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEYKKSDDTDWKTSIQ-SLRG 19834
Query: 1866 SSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENV----------SPPRRARVTD 1915
+ +SGL +Y V ++ S P+ + S R+ +
Sbjct: 19835 TEYTISGLTTGAEYVFRVKSVNKVGASDPSDSSDPQIAKEREEEPLFDIDSEMRKTLIVK 19894
Query: 1916 A-TETTITISWRTK-----------TETITGFQVDAVPANGQTPIQRTIKPDVRSYTITG 1963
A T+T+ +R + T+ T VD + I+ + D YT+T
Sbjct: 19895 AGASFTMTVPFRGRPVPNVLWSKPDTDLRTRAYVDTTDSRTSLTIENANRNDSGKYTLT- 19953
Query: 1964 LQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPP 2017
+Q +A S +V+ P+N+ T S ++SW P
Sbjct: 19954 IQNVL-----------SAASLTLVVKVLDTPGPPTNITVQDVTKESAVLSWDVP 19996
Score = 102 bits (255), Expect = 4e-21
Identities = 136/661 (20%), Positives = 242/661 (36%), Gaps = 91/661 (13%)
Query: 1514 EYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVT----VRYY 1569
+Y + +G++ + +L+ T P ++V + S+ I+W+ P + V Y
Sbjct: 23209 KYTIEAENQSGKKSATVLVKVYDTPGPCP-SVKVKEVSRDSVTITWEIPTIDGGAPVNNY 23267
Query: 1570 RITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYA--VTGRGDSPASSKPISI 1627
+ E + + T SK+ ISGL G Y V + G G+ +S + +
Sbjct: 23268 IVEKREAAMRA-FKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYGIGEPCETSDAVLV 23326
Query: 1628 NYRTEIDKPSQMQVTDVQDNSISVKW----LPSSSPVTGYRVTTTPKNGPGPTKTKTAGP 1683
+ + P++++V DV +++++ W S +TGY + K T P
Sbjct: 23327 SEVPLV--PAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGTERWMKVVTLKP 23384
Query: 1684 DQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAW 1743
E T+ L +Y+ + AQN G S+P + + L D+ K
Sbjct: 23385 TVLEHTVTSLNEGEQYLFRIRAQNEKGVSEPRETVTAVTVQDLRVLPTIDLSTMPQKTI- 23443
Query: 1744 ESPQGQVSRYRVTYSSPEDGIHELFPAPDG--EEDTAELQGLRPGSEYTVSVVALHDD-- 1799
P G+ + + F A E + ++ ++ T+ + D
Sbjct: 23444 HVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAKLTIRETTIRDTGE 23503
Query: 1800 --MESQPLIGTQSTAI---------PAPTDLKFTQVTPTSLSAQWTPPNVQ----LTGYR 1844
+E + + GT S I P +K ++ TS++ W PP + L+GY
Sbjct: 23504 YTLELKNVTGTTSETIKVIILDKPGPPTGPIKIDEIDATSITISWEPPELDGGAPLSGYV 23563
Query: 1845 VRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLEN 1904
V + G + P S SV S E + Y + T+R G E
Sbjct: 23564 VEQRDAHRPGWL------PVSESVTRSTFKFTRLTEGNEYVFRVAATNRFGIGSYLQSEV 23617
Query: 1905 VS---------PPRRARVTDATETTITISWRTKTET----ITGFQVDAVPANGQTPIQRT 1951
+ PP ++ D + +T++W + +TG+ V+ ++
Sbjct: 23618 IECRSSIRIPGPPETLQIFDVSRDGMTLTWYPPEDDGGSQVTGYIVERKEVRADRWVRVN 23677
Query: 1952 IKP-DVRSYTITGLQPGTDYKIYLYTLNDNARSSP-------VVIDASTAIDAPSNLRFL 2003
P + Y TGL G +Y+ + +N P V +D P N R
Sbjct: 23678 KVPVTMTRYRSTGLTEGLEYEHRVTAINARGSGKPSRPSKPIVAMDPIAPPGKPQNPRVT 23737
Query: 2004 ATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTE 2059
TT S+ ++W P +++TGY+I+ +K + E T+T L G E
Sbjct: 23738 DTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTKCNTTPTKIREYTLTHLPQGAE 23797
Query: 2060 YTIYVIALKNNQKSEPLIGRKKTDELPQLVTLPHPNLHGPEILDVPSTVQKTPFVTHPGY 2119
Y V+A EP +VP TV+ T + +P Y
Sbjct: 23798 YRFRVLACNAGGPGEP--------------------------AEVPGTVKVTEMLEYPDY 23831
Query: 2120 D 2120
+
Sbjct: 23832 E 23832
Score = 100 bits (248), Expect = 2e-20
Identities = 162/726 (22%), Positives = 275/726 (37%), Gaps = 92/726 (12%)
Query: 1268 PQLTDLSFVDITDSSIGLRWTPLN---SSTIIGYRITVVAAGEG--IPIFEDFVDSSVGY 1322
P + +I +SI + W P + + GY + A +P+ E S+
Sbjct: 23529 PPTGPIKIDEIDATSITISWEPPELDGGAPLSGYVVEQRDAHRPGWLPVSESVTRST--- 23585
Query: 1323 YTVTGLEPGIDYDISVITLINGG-----ESAPTTLTQQTAVP-PPTDLRFTNIGPDTMRV 1376
+ T L G +Y V G +S +P PP L+ ++ D M +
Sbjct: 23586 FKFTRLTEGNEYVFRVAATNRFGIGSYLQSEVIECRSSIRIPGPPETLQIFDVSRDGMTL 23645
Query: 1377 TWAPPPS---IDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVY 1433
TW PP +T ++V V+ + V + + T L G EY V+++
Sbjct: 23646 TWYPPEDDGGSQVTGYIVERKEVRADRWVRVNKVPVTMTRYRSTGLTEGLEYEHRVTAIN 23705
Query: 1434 EQHESTPLR-GRQKTGLD------SPTGIDFSDITANSFTVHWIAPR----ATITGYRIR 1482
+ P R + +D P +D T S ++ W P + +TGY I
Sbjct: 23706 ARGSGKPSRPSKPIVAMDPIAPPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIE 23765
Query: 1483 HHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVP 1542
+ + P TLT+L G EY ++A N G ++VP
Sbjct: 23766 MQKVDQHEWTKCNTTPTKIREYTLTHLPQGAEYRFRVLACNA--------GGPGEPAEVP 23817
Query: 1543 RDLEVVAAT--PTSLLISWDAPAVTVRY---YRITYGETGGNSPVQEFTVPGSKSTATIS 1597
++V P L + VR R+T G P+ ++T G + + +
Sbjct: 23818 GTVKVTEMLEYPDYELDERYQEGIFVRQGGVIRLTIPIKGKPFPICKWTKEG-QDISKRA 23876
Query: 1598 GLKPGVDYTITVYAVTGRGDS---------PASSKPISINYRTEIDKPSQ----MQVTDV 1644
+ +T V RGDS K + I R I P+ ++ D+
Sbjct: 23877 MIATSETHTELVIKEADRGDSGTYDLVLENKCGKKAVYIKVRV-IGSPNSPEGPLEYDDI 23935
Query: 1645 QDNSISVKWLPSS----SPVTGYRVTT--TPKNGPGPTKTKTAGPDQTEMTIEGLQPTVE 1698
Q S+ V W P + + + GY + PK ++ G T + ++GL+ VE
Sbjct: 23936 QVRSVRVSWRPPADDGGADILGYILERREVPKAAWYTIDSRVRG---TSLVVKGLKENVE 23992
Query: 1699 YVVSVYAQNPSGESQPLVQ----TAVTNIDRPKGLA----FTDVDVDSIKIAWESPQGQ- 1749
Y V A+N G S+PL T T ++ P+ + DV S+ ++W P+
Sbjct: 23993 YHFRVSAENQFGISKPLKSEEPVTPKTPLNPPEPPSNPPEVLDVTKSSVSLSWSRPKDDG 24052
Query: 1750 VSRYRVTYSSPEDGIHELFPAPDGEEDTAEL---QGLRPGSEYTVSVVALHD------DM 1800
SR Y ++ + + + + T + GL P +EY ++A +D
Sbjct: 24053 GSRVTGYYIERKETSTDKWVRHNKTQITTTMYTVTGLVPDAEYQFRIIAQNDVGLSETSP 24112
Query: 1801 ESQPLIGTQSTAIPA-PTDLKFTQVTPTSLSAQWTPPNV----QLTGYRVRVTPKEKTGP 1855
S+P++ P+ P +L+ ++ S++ QW P ++ GY V +
Sbjct: 24113 ASEPVVCKDPFDKPSQPGELEILSISKDSVTLQWEKPECDGGKEILGYWVEYRQSGDSAW 24172
Query: 1856 MKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRP---AQGVVTTL-ENVSPPRRA 1911
K + GL+ AT+YE V+A +T SRP A + T L +P R
Sbjct: 24173 KKSNKERIKDKQFTIGGLLEATEYEFRVFAENETGLSRPRRTAMSIKTKLTSGEAPGIRK 24232
Query: 1912 RVTDAT 1917
+ D T
Sbjct: 24233 EMKDVT 24238
Score = 99.8 bits (247), Expect = 3e-20
Identities = 244/1107 (22%), Positives = 422/1107 (38%), Gaps = 171/1107 (15%)
Query: 1092 PPYNTEVTET---TIVITWT-PAPRIGFKLGVRPSQGGEAPREV------TSDSGSIVVS 1141
P N EVTET + + W P G K+ + + R+ ++S V+
Sbjct: 6787 PVRNLEVTETFDGEVSLAWEEPLTDGGSKIIGYVVERRDIKRKTWVLATDRAESCEFTVT 6846
Query: 1142 GLTPG-VEYVYTIQVLR-----DGQERDAPIV--NKVVTPLSPPTNLHLEANPDTGVLTV 1193
GL G VEY++ + + E D P+ +K P PP N+ + GV ++
Sbjct: 6847 GLQKGGVEYLFRVSARNRVGTGEPVETDNPVEARSKYDVP-GPPLNVTITDVNRFGV-SL 6904
Query: 1194 SWERSTTP---DITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYT- 1249
+WE +IT Y I + ++ V A+ S T ++ G EY+ V
Sbjct: 6905 TWEPPEYDGGAEITNYVIELRDKTSIRWDTAM-TVRAEDLSATVTDVVEGQEYSFRVRAQ 6963
Query: 1250 --VKDDKES-----VPISDTIIPEVPQLTDLSFVDITDSSIGLRWTPL---NSSTIIGYR 1299
+ K S V ++D I P + +L+ D T SS+ L+W P S I+GY
Sbjct: 6964 NRIGVGKPSAATPFVKVADPIERPSPPV-NLTSSDQTQSSVQLKWEPPLKDGGSPILGYI 7022
Query: 1300 ITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLT------ 1353
I G+ I + Y VTGLE G Y V G S P+ +
Sbjct: 7023 IERCEEGKDNWIRCNMKLVPELTYKVTGLEKGNKYLYRVSAENKAGVSDPSEILGPLTAD 7082
Query: 1354 ----------------QQTAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVK 1397
+ VP P + + G TW + T V+ +K
Sbjct: 7083 DAFVEPTMDLSAFKDGLEVIVPNPITILVPSTGYPRPTATWCFGDKVLETGDRVK---MK 7139
Query: 1398 NEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHE-STPLRGRQKTGLDSPTGID 1456
AEL ISPS+ + L V ++S + + + P +P +
Sbjct: 7140 TLSAYAELVISPSERSDKGIYTLKLENRVKTISGEIDVNVIARP---------SAPKELK 7190
Query: 1457 FSDITANSFTVHWIAP----RATITGYRIRHHPEHFSGRPREDRVPHSRNSI--TLTNLT 1510
F DIT +S + W P + +TGY + + R +V + T+ +L
Sbjct: 7191 FGDITKDSVHLTWEPPDDDGGSPLTGYVVE---KREVSRKTWTKVMDFVTDLEFTVPDLV 7247
Query: 1511 PGTEYVVSIVALN-------GREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAP- 1562
G EY+ + A N + P+ + +TV D P +++ T S+ ++WD P
Sbjct: 7248 QGKEYLFKVCARNKCGPGEPAYVDEPVNMSTPATVPDPPENVKWRDRTANSIFLTWDPPK 7307
Query: 1563 ---AVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSP 1619
++ Y + G + V P +++ ++GL+ G Y V A+ +G
Sbjct: 7308 NDGGSRIKGYIVERCPRGSDKWV-ACGEPVAETKMEVTGLEEGKWYAYRVKALNRQG--- 7363
Query: 1620 ASSKPISINYRTEIDKPS-QMQVTDVQDNS---ISVKWLPSSSPVTGYRV----TTTPKN 1671
+SKP +P+ ++Q D Q+ + VK L + G ++ T T K
Sbjct: 7364 -ASKP---------SRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKP 7413
Query: 1672 GPGPTKTKT--AGPDQTEMTIEGL--QPTVEYVVS---------VYAQNPSGESQPLVQT 1718
P T TK +TIE + + TV V S + A N G + +V+
Sbjct: 7414 EPKITWTKADMILKQDKRITIENVPKKSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEV 7473
Query: 1719 AVTNIDR---PKGLAFTDVDVDSIKIAWESPQ----GQVSRYRVTYSSPEDGI-HELFPA 1770
V +D+ P TDV +S + W P+ +++ Y V + + + H+L +
Sbjct: 7474 NV--LDKPGPPAAFDITDVTNESCLLTWNPPRDDGGSKITNYVVERRATDSEVWHKL--S 7529
Query: 1771 PDGEEDTAELQGLRPGSEYTVSVVA-----LHDDMESQPLIGTQSTAIPA-PTDLKFTQV 1824
++ + L P EY V A + + +++ P+ P PT L+ + +
Sbjct: 7530 STVKDTNFKATKLIPNKEYIFRVAAENMYGVGEPVQASPITAKYQFDPPGPPTRLEPSDI 7589
Query: 1825 TPTSLSAQWTPPN----VQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYE 1880
T +++ W P+ +TGY V + ++ + ++ V GL KY
Sbjct: 7590 TKDAVTLTWCEPDDDGGSPITGYWVERLDPDTDKWVRCNKMPVKDTTYRVKGLTNKKKYR 7649
Query: 1881 VSVYALKDTLTSRPAQG-----VVTTLENVSPPRRARVTDATETTITISWRTKTE----- 1930
V A +P++ + ++ PP + V D +T++ ++W TK E
Sbjct: 7650 FRVLAENLAGPGKPSKSTEPILIKDPIDPPWPPGKPTVKDVGKTSVRLNW-TKPEHDGGA 7708
Query: 1931 TITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPV---- 1986
I + ++ + ++ + + GL G +Y + +N S P
Sbjct: 7709 KIESYVIEMLKTGTDEWVRVAEGVPTTQHLLPGLMEGQEYSFRVRAVNKAGESEPSEPSD 7768
Query: 1987 VIDASTAIDAPSNLRFLAT---TPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREVV 2039
+ + PS R+L T N+ + W P + IT YI++ + V
Sbjct: 7769 PVLCREKLYPPSPPRWLEVINITKNTADLKWTVPEKDGGSPITNYIVEKRDVRRKGWQTV 7828
Query: 2040 PRPRPGVTEATITGLEPGTEYTIYVIA 2066
T+ T+T L G+ Y V A
Sbjct: 7829 DTTVKD-TKCTVTPLTEGSLYVFRVAA 7854
Score = 99.8 bits (247), Expect = 3e-20
Identities = 292/1340 (21%), Positives = 474/1340 (35%), Gaps = 235/1340 (17%)
Query: 908 PSP-RDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTG 966
P P R+L+ V+V+ + T+ W PPE G + N E + + +T++ T
Sbjct: 11992 PGPVRNLKIVDVSSDRCTVCWDPPEDD-GGCEIQ----NYILEKCETKRMVWSTYS-ATV 12045
Query: 967 LSPGVT---------YYFKVFA-----VSHGRESKPLTAQQTTKLDA-----PTNLQFVN 1007
L+PG T Y F+V A ESKP+ A+ TK D P + V+
Sbjct: 12046 LTPGTTVTRLIEGNEYIFRVRAENKIGTGPPTESKPVIAK--TKYDKPGRPDPPEVTKVS 12103
Query: 1008 ETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSV---SKYPLRNLQPAS 1060
+ + TV+ W PP ITGY L + R V S + ++NL P
Sbjct: 12104 KEEMTVV--WNPPEYDGGKSITGYFLE--KKEKHSTRWVPVNKSAIPERRMKVQNLLPDH 12159
Query: 1061 EYTVSLVAIK----GNQESPKATGVF-TTLQPGSSIPPYNTEVTETT---IVITWTP--- 1109
EY + A G P V ++P PP N V +TT I + W
Sbjct: 12160 EYQFRVKAENEIGIGEPSLPSRPVVAKDPIEPPG--PPTNFRVVDTTKHSITLGWGKPVY 12217
Query: 1110 ---APRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPI 1166
AP IG+ + +RP +P D G + V +T+ L + QE + +
Sbjct: 12218 DGGAPIIGYVVEMRPKIADASP-----DEGWKRCNAAAQLVRKEFTVTSLDENQEYEFRV 12272
Query: 1167 VNKVVTPLSPPTNLHLEANP-----------DTGVLTVSWERSTTPD--ITGYRITTTPT 1213
+ + P L P D + + R+ P R P
Sbjct: 12273 CAQNQVGIGRPAELKEAIKPKEILEPPEIDLDASMRKLVIVRAGCPIRLFAIVRGRPAPK 12332
Query: 1214 NGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDD-------------KESVPIS 1260
+ ++ VV Q +L + + V + +DD +++V ++
Sbjct: 12333 VTWRKVGIDNVVRKGQV-----DLVDTMAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFVN 12387
Query: 1261 DTIIPEVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGYRIT--VVAAGEGIPIFEDFVDS 1318
++ ++DL D+T +S + W P + G ++T +V E V
Sbjct: 12388 VRVLDTPGPVSDLKVSDVTKTSCHVSWAPPENDG--GSQVTHYIVEKREADRKTWSTVTP 12445
Query: 1319 SV--GYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAV-------PPPTDLRFTNI 1369
V + VT L PG +Y V + G PT + + PP L T +
Sbjct: 12446 EVKKTSFHVTNLVPGNEYYFRVTAVNEYGPGVPTDVPKPVLASDPLSEPDPPRKLEVTEM 12505
Query: 1370 GPDTMRVTWAPP---PSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYV 1426
++ + W PP + ++ Y + D D ++V+T L G +Y
Sbjct: 12506 TKNSATLAWLPPLRDGGAKIDGYITSYREEEQPADRWTEYSVVKDLSLVVTGLKEGKKYK 12565
Query: 1427 VSVSSVYEQHESTPLRG----RQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIR 1482
V++ S P K L P + IT + G ++R
Sbjct: 12566 FRVAARNAVGVSLPREAEGVYEAKEQLLPPKILMPEQITIKA-------------GKKLR 12612
Query: 1483 HHPEHFSGRPR--------EDRV----------PHSRNSITLTNLTPGTEYVVSIVALNG 1524
H G+P ED V S + + + ++T S+ A N
Sbjct: 12613 IE-AHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGYYSLTAENS 12671
Query: 1525 ----REESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAP----AVTVRYYRITYGET 1576
++ +++ P D+ + A SL SW P + Y + +
Sbjct: 12672 SGTDTQKIKVVVMDAPGPPQPPFDISDIDADACSL--SWHIPLEDGGSNITNYIVEKCDV 12729
Query: 1577 GGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDS-PASSKPISINYRTEI-D 1634
V +K++ + L PG +Y V A G S P +S + + +
Sbjct: 12730 SRGDWVTAL-ASVTKTSCRVGKLIPGQEYIFRVRAENRFGISEPLTSPKMVAQFPFGVPS 12788
Query: 1635 KPSQMQVTDVQDNSISVKW-LPSS---SPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTI 1690
+P +VT V + I V W P S SP+ GY + +N K TE
Sbjct: 12789 EPKNARVTKVNKDCIFVAWDRPDSDGGSPIIGYLIERKERNSLLWVKANDTLVRSTEYPC 12848
Query: 1691 EGLQPTVEYVVSVYAQNPSGESQPL----VQTAVTNIDRPKGLAFTDVDVDSIKIAWESP 1746
GL +EY +YA N +G S P TA +D P DV ++ + W P
Sbjct: 12849 AGLVEGLEYSFRIYALNKAGSSPPSKPTEYVTARMPVDPPGKPEVIDVTKSTVSLIWARP 12908
Query: 1747 QGQVSRYRVTY-----SSPEDGIHELFPAP---DGEEDTAELQGLRPGSEYTVSVVALHD 1798
+ + Y P D AP EE TA GL ++Y +A
Sbjct: 12909 KHDGGSKIIGYFVEACKLPGDKWVRCNTAPHQIPQEEYTA--TGLEEKAQYQFRAIARTA 12966
Query: 1799 DMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLT-GYRVRVTPKEKTG--- 1854
S P P+D P ++ A+ PP + L+ + +T K T
Sbjct: 12967 VNISPP---------SEPSD-------PVTILAENVPPRIDLSVAMKSLLTVKAGTNVCL 13010
Query: 1855 -------PMKEINLAPDSSSV-VVSGLMVATKYEVSVYAL-----KD----TLTSRPAQG 1897
PM ++ D + + G+ +A + + L KD T+T+ + G
Sbjct: 13011 DATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTITAENSSG 13070
Query: 1898 ------VVTTLENVSPPRRARVTDATETTITISWRTKTE----TITGFQVDAVPANGQTP 1947
+ L+ PP ++ +SW E IT + VD +
Sbjct: 13071 SKSATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYIVDKRETSRPNW 13130
Query: 1948 IQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVID---ASTAIDAPSNLR--- 2001
Q + + S ++ L G +Y+ + N PV + A D P
Sbjct: 13131 AQVSATVPITSCSVEKLIEGHEYQFRICAENKYGVGDPVFTEPAIAKNPYDPPGRCDPPV 13190
Query: 2002 FLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREVVPRPRPGVTEATI--TGLE 2055
T + + VSW+PP + ITGY++ EK + R + E T+ TGL+
Sbjct: 13191 ISNITKDHMTVSWKPPADDGGSPITGYLL--EKRETQAVNWTKVNRKPIIERTLKATGLQ 13248
Query: 2056 PGTEYTIYVIALKNNQKSEP 2075
GTEY V A+ +P
Sbjct: 13249 EGTEYEFRVTAINKAGPGKP 13268
Score = 98.6 bits (244), Expect = 7e-20
Identities = 157/730 (21%), Positives = 276/730 (37%), Gaps = 78/730 (10%)
Query: 785 KYIVNVYQISEDGEQSLIL-----STSQTTAP---DAPPDPT----VDQVDDTSIVVRWS 832
K + I + GE +L L +TS+T D P PT +D++D TSI + W
Sbjct: 23490 KLTIRETTIRDTGEYTLELKNVTGTTSETIKVIILDKPGPPTGPIKIDEIDATSITISWE 23549
Query: 833 RPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQE 888
P+ AP++GY + + ++ T ++ + L G +Y + A N+
Sbjct: 23550 PPELDGGAPLSGYVVEQRDAHRPGWLPVSESVTRSTFKFTRLTEGNEYVFRVAAT--NRF 23607
Query: 889 STPVVIQQETTGTPRSDTVPSPRD-LQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIP 943
+Q E S +P P + LQ +V+ +T+ W PPE S VTGY V+
Sbjct: 23608 GIGSYLQSEVIECRSSIRIPGPPETLQIFDVSRDGMTLTWYPPEDDGGSQVTGYIVERKE 23667
Query: 944 VNLPG-EHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSH------GRESKPLTAQQTTK 996
V ++P++ + TGL+ G+ Y +V A++ R SKP+ A
Sbjct: 23668 VRADRWVRVNKVPVTMTRYRS-TGLTEGLEYEHRVTAINARGSGKPSRPSKPIVAMDPIA 23726
Query: 997 LDA-PTNLQFVNETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPS-VSK 1050
P N + + T ++V + W+ P +++TGY + + + + + N P+ + +
Sbjct: 23727 PPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTKCNTTPTKIRE 23786
Query: 1051 YPLRNLQPASEYTVSLVAIK-GNQESPKATGVFTTLQPGSSIPPYNTE--------VTET 1101
Y L +L +EY ++A G P + P Y + V +
Sbjct: 23787 YTLTHLPQGAEYRFRVLACNAGGPGEPAEVPGTVKVTEMLEYPDYELDERYQEGIFVRQG 23846
Query: 1102 TIVITWTPAPRIGFKLGVRPSQGGEAPREV---TSDSGS-IVVSGLTPGVEYVYTIQVLR 1157
++ P F + +G + + TS++ + +V+ G Y + +
Sbjct: 23847 GVIRLTIPIKGKPFPICKWTKEGQDISKRAMIATSETHTELVIKEADRGDSGTYDLVLEN 23906
Query: 1158 DGQERDAPIVNKVV-TPLSPPTNLHLEANPDTGVLTVSWERSTTP---DITGYRITTTPT 1213
++ I +V+ +P SP L + + + VSW DI GY +
Sbjct: 23907 KCGKKAVYIKVRVIGSPNSPEGPLEYD-DIQVRSVRVSWRPPADDGGADILGYILERREV 23965
Query: 1214 NGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKD--------DKESVPISDTIIP 1265
+++ V +S L +EY+ V +E V + P
Sbjct: 23966 PKAAWYTIDSRVRG--TSLVVKGLKENVEYHFRVSAENQFGISKPLKSEEPVTPKTPLNP 24023
Query: 1266 EVPQLTDLSFVDITDSSIGLRWT---PLNSSTIIGYRITVVAAGEGIPIFEDFVDSSVGY 1322
P +D+T SS+ L W+ S + GY I + + +
Sbjct: 24024 PEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRVTGYYIERKETSTDKWVRHNKTQITTTM 24083
Query: 1323 YTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAVPPPTD-------LRFTNIGPDTMR 1375
YTVTGL P +Y +I + G S + ++ P D L +I D++
Sbjct: 24084 YTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCKDPFDKPSQPGELEILSISKDSVT 24143
Query: 1376 VTWAPPP---SIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSV 1432
+ W P ++ + V Y + D + LL TEY V +
Sbjct: 24144 LQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERIKDKQFTIGGLLEATEYEFRVFAE 24203
Query: 1433 YEQHESTPLR 1442
E S P R
Sbjct: 24204 NETGLSRPRR 24213
Score = 96.3 bits (238), Expect = 3e-19
Identities = 294/1454 (20%), Positives = 518/1454 (35%), Gaps = 209/1454 (14%)
Query: 684 IQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSA 743
I+ G Q + + + S P+T + P PL VT +TA ++W
Sbjct: 18467 IRTDGGQYILKLSNVGGTKSIPITVKVLDRPGPPEGPL-----KVTGVTAEKCYLAWNPP 18521
Query: 744 SDTVSGFRVEYELSEEGDEPQYLDLPSTATSVN-----IPDLLPGRKYI-----VNVYQI 793
G + + + E+ E L +T V + LLPG +YI VN Y I
Sbjct: 18522 LQD-GGANISHYIIEKR-ETSRLSWTQVSTEVQALNYKVTKLLPGNEYIFRVMAVNKYGI 18579
Query: 794 SEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRP----QAPITGYRIVYSPSV 849
E E + + + P P P V + S+VV W+RP I GY I+
Sbjct: 18580 GEPLESGPVTACNPYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGY-ILEKRDK 18638
Query: 850 EGSSTELNLPETANSVTL--SDLQPGVQYNITIYAVEE---NQESTPVVIQQETTGTPRS 904
EG +T + L + L G Y + A + S P V +
Sbjct: 18639 EGVRWTKCNKKTLTDLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYR------AC 18692
Query: 905 DTVPSPRDLQFVEVTDV---KVTIMWTPP----ESAVTGYRVDV------------IPVN 945
D + P +VTD V++ W+ P + V GY V+V P
Sbjct: 18693 DALYPPGPPSNPKVTDTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAADEWTTCTPPTG 18752
Query: 946 LPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLT------AQQ-----T 994
L G+ VT L Y F++ A++ +P T AQ+
Sbjct: 18753 LQGKQ-----------FTVTKLKENTEYNFRICAINSEGVGEPATLPGSVVAQERIEPPE 18801
Query: 995 TKLDAPTNLQFVNETDSTVLVRWT---PPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKY 1051
+LDA V +T+ + T P ++ + LT R Q V S +
Sbjct: 18802 IELDADLRKVVVLRASATLRLFVTIKGRPEPEVKWEKAEGILTDRA---QIEVTSSFTML 18858
Query: 1052 PLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAP 1111
+ N+ +L + V P + + EV + ++ ++W P
Sbjct: 18859 VIDNVTRFDSGRYNLTLENNSGSKTAFVNVRVLDSPSAPVNLTIREVKKDSVTLSWEPPL 18918
Query: 1112 RIGFKLGVRPSQGGEAPREVTSDSGSIV----------VSGLTPGVEYVYTIQVLRD--- 1158
G G + + RE T + + + + L G Y + + +
Sbjct: 18919 IDG---GAKITNYIVEKRETTRKAYATITNNCTKTTFRIENLQEGCSYYFRVLASNEYGI 18975
Query: 1159 GQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT---PDITGYRITTTPTNG 1215
G + KV P PP + L + T+ WE+ + ITGY +
Sbjct: 18976 GLPAETTEPVKVSEPPLPPGRVTL-VDVTRNTATIKWEKPESDGGSKITGYVVEMQTKGS 19034
Query: 1216 QQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPEVPQLTDLSF 1275
++ ++ +V + T L+ G EY V V + S P +P + + ++
Sbjct: 19035 EKWSTCTQVKTLE---ATISGLTAGEEYVFRVAAVNEKGRSDP-RQLGVPVIARDIEIK- 19089
Query: 1276 VDITDSSIGLRWTPLNSSTIIGYRITVVAAG----------EGIPIFEDFVDSSVGYYTV 1325
S+ L + N +I V G +G + E + TV
Sbjct: 19090 -----PSVELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTV 19144
Query: 1326 TGL--EPGIDYDISVITLI----NGGESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTWA 1379
T L + D+ L G + P T+ PP +R + D++ ++W
Sbjct: 19145 TSLSIKEASKEDVGTYELCVSNSAGSITVPITIIVLDRPGPPGPIRIDEVSCDSITISWN 19204
Query: 1380 PPP---SIDLTNFLVRYSPVKNEEDVAE---LSISPSDNAVVLTNLLPGTEYVVSVSS-- 1431
PP ++N++V K E +S + + ++ + L G+EY V +
Sbjct: 19205 PPEYDGGCQISNYIVE----KKETTSTTWHIVSQAVARTSIKIVRLTTGSEYQFRVCAEN 19260
Query: 1432 ---VYEQHESTPLRGRQKTGLDSPTGI-DFSDITANSFTVHWIAP----RATITGYRIRH 1483
ES+ + P G T ++ V W P + + GY + +
Sbjct: 19261 RYGKSSYSESSAVVAEYPFSPPGPPGTPKVVHATKSTMLVTWQVPVNDGGSRVIGYHLEY 19320
Query: 1484 HPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN----GREESPLLIGQQSTVS 1539
+ +++ + + ++ L G Y + A N G+
Sbjct: 19321 KERSSILWSKANKILIADTQMKVSGLDEGLMYEYRVYAENIAGIGKCSKSCEPVPARDPC 19380
Query: 1540 DVPRDLEVVAATPTSLLISWDAP----AVTVRYYRITYGETGGNSPVQEFTVPGSKSTAT 1595
D P EV T S+ + W P + Y + E ++ ++
Sbjct: 19381 DPPGQPEVTNITRKSVSLKWSKPHYDGGAKITGYIVERRELPDGRWLKCNYTNIQETYFE 19440
Query: 1596 ISGLKPGVDYTITVYAVTGRGD-SPASSKPISINYRTEIDKPSQMQVTDVQDNSI--SVK 1652
++ L Y V+A S S I + +++ P M +D + + +
Sbjct: 19441 VTELTEDQRYEFRVFARNAADSVSEPSESTGPIIVKDDVEPPRVMMDVKFRDVIVVKAGE 19500
Query: 1653 WLPSSSPVTG--YRVTTTPKNG---PGPTKTKTAGPD-QTEMTIEGL--QPTVEYVVSVY 1704
L ++ + G V + K+G +T+ D T +T++ + T +YV+++
Sbjct: 19501 VLKINADIAGRPLPVISWAKDGIEIEERARTEIISTDNHTLLTVKDCIRRDTGQYVLTL- 19559
Query: 1705 AQNPSGESQPLVQTAVTNIDRPKG--LAFTDVDVDSIKIAWESPQ----GQVSRYRVTYS 1758
+N +G V V + P L + + ++W PQ + Y V
Sbjct: 19560 -KNVAGTRSVAVNCKVLDKPGPPAGPLEINGLTAEKCSLSWGRPQEDGGADIDYYIV--- 19615
Query: 1759 SPEDGIHELFPAPDGE--EDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPA- 1815
+ H + +GE + ++ L G+EY V ++ +PL +S AI A
Sbjct: 19616 EKRETSHLAWTICEGELQMTSCKVTKLLKGNEYIFRVTGVNKYGVGEPL---ESVAIKAL 19672
Query: 1816 --------PTDLKFTQVTPTSLSAQWTPP----NVQLTGYRVRVTPKEKTGPMKEINLAP 1863
PT L+ T VT S++ W+ P +++GY + K ++
Sbjct: 19673 DPFTVPSPPTSLEITSVTKESMTLCWSRPESDGGSEISGYIIERREKNSLRWVRVNKKPV 19732
Query: 1864 DSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQ--GVVTTLENV---SPPRRARVTDATE 1918
V +GL +YE VYA S P++ ++ + V SPP + ++ D+ +
Sbjct: 19733 YDLRVKSTGLREGCEYEYRVYAENAAGLSLPSETSPLIRAEDPVFLPSPPSKPKIVDSGK 19792
Query: 1919 TTITISWRTKT----ETITGFQVD---AVPANGQTPIQRTIKPDVRSYTITGLQPGTDYK 1971
TTITI+W ITG+ V+ + + +T IQ + YTI+GL G +Y
Sbjct: 19793 TTITIAWVKPLFDGGAPITGYTVEYKKSDDTDWKTSIQSLRGTE---YTISGLTTGAEYV 19849
Query: 1972 IYLYTLNDNARSSP 1985
+ ++N S P
Sbjct: 19850 FRVKSVNKVGASDP 19863
Score = 95.5 bits (236), Expect = 6e-19
Identities = 319/1473 (21%), Positives = 540/1473 (36%), Gaps = 232/1473 (15%)
Query: 777 IPDLLPGRKYIVNVYQISEDG--EQSLILSTSQTTAPDAPPD------PTVDQVDDTSIV 828
+ DL+ G +Y V ++ G + S + PD PP V++ + +IV
Sbjct: 9773 VEDLVEGGEYEFRVKAVNAAGVSKPSATVGPCDCQRPDMPPSIDLKEFMEVEEGTNVNIV 9832
Query: 829 VR----------WSR--PQAPITGYRIVYSPSVE----GSSTELNLPETANSVTLSDLQP 872
+ W + P+ P ++Y V + L +P++ S T
Sbjct: 9833 AKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDT------ 9886
Query: 873 GVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE- 931
G+ TI AV N + ++ G P P ++F V+ ++T+ W PP+
Sbjct: 9887 GLY---TITAVN-NLGTASKEMRLNVLGRPGPPVGP----IKFESVSADQMTLSWFPPKD 9938
Query: 932 ---SAVTGYRVDVIPVNLPG-EHGQRLPISRNTFAEVTGLSPGVTYYFKVFA-----VSH 982
S +T Y ++ N H P + + L G Y F++ A +
Sbjct: 9939 DGGSKITNYVIEKREANRKTWVHVSSEP--KECTYTIPKLLEGHEYVFRIMAQNKYGIGE 9996
Query: 983 GRESKPLTAQQTTKLD-APTNLQFVNETDSTVLVRWTPPR----AQITGYRLTVGLTRRG 1037
+S+P TA+ + AP + T +++ V W P + +TGY L + T
Sbjct: 9997 PLDSEPETARNLFSVPGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPVTGYWLEMKDTTSK 10056
Query: 1038 QPRQYNVGPSVS-----KYPLRNLQPASEYTVSLVAIKGNQESPK------ATGVFTTLQ 1086
+ ++ N P + Y + L S+Y + AI P AT
Sbjct: 10057 RWKRVNRDPIKAMTLGVSYKVTGLIEGSDYQFRVYAINAAGVGPASLPSDPATARDPIAP 10116
Query: 1087 PGSSIPPYNTEVTETTIVITWTPAPRIGFKLG----VRPSQGGEAPREVTSDSG----SI 1138
PG P T+ T+++ + W+P + G V + G+ E D +
Sbjct: 10117 PGPPFPKV-TDWTKSSADLEWSPPLKDGGSKVTGYIVEYKEEGKEEWEKGKDKEVRGTKL 10175
Query: 1139 VVSGLTPGVEYVYTIQVLRD---GQERDAPIVNKVVTPLSPPTNLHLEANP-DTGVLTVS 1194
VV+GL G Y + ++ + G+ + V ++ L P +L L+A+ D V+
Sbjct: 10176 VVTGLKEGAFYKFRVRAVNIAGIGEPGEVTDVIEMKDRLVSP-DLQLDASVRDRIVVHAG 10234
Query: 1195 WERSTTPDITGYRITTTPTNGQQGNSLEEVV---HADQSSCTFDNLSPGLEYNVSVYTVK 1251
++G T N + +E A SS N + VY++
Sbjct: 10235 GVIRIIAYVSGKPPPTVTWNMNERTLPQEATIETTAISSSMVIKNCQRSHQ---GVYSLL 10291
Query: 1252 DDKESVPISDTIIPEV-----PQLTDLSFVDITDSSIGLRW-TPLNS--STIIGYRITVV 1303
E+ TII +V P T ++T+ S L W +P + S I Y I
Sbjct: 10292 AKNEAGERKKTIIVDVLDVPGPVGTPFLAHNLTNESCKLTWFSPEDDGGSPITNYVIEKR 10351
Query: 1304 AAGEGI--PIFEDFVDSSVGYYTVTGLEPGIDY--DISVITLINGGESAPTT----LTQQ 1355
+ P+ + TV GL G Y I+ I G T+ + +
Sbjct: 10352 ESDRRAWTPVTYTVTRQNA---TVQGLIQGKAYFFRIAAENSIGMGPFVETSEALVIREP 10408
Query: 1356 TAVPP-PTDLRFTNIGPDTMRVTWAPPP---SIDLTNFLVRYSPVKNEEDVAELSISPSD 1411
VP P DL + +T+ +TW PP ++ N+++ + E+ + +
Sbjct: 10409 ITVPERPEDLEVKEVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEKFHKVTNDNLLS 10468
Query: 1412 NAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQ----KTGLDSPT-GIDFSDITANSFT 1466
+ L G Y VS+V + P + K L PT +DF D T
Sbjct: 10469 RKYTVKGLKEGDTYEYRVSAVNIVGQGKPSFCTKPITCKDELAPPTLHLDFRD----KLT 10524
Query: 1467 VHWIAPRATITGYRIRHHPEHFSGRPR------EDRVPHSRNSITLTNLTPGTEYVVSIV 1520
+ + +TG +SG+P+ +D + T TP T + I
Sbjct: 10525 IR-VGEAFALTG--------RYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATLALEKIK 10575
Query: 1521 ALNGREESPLLIGQQST--------VSDVPRDLEVVA------ATPTSLLISWDAP---- 1562
A ++ + ST V+ V R V T ++ISW P
Sbjct: 10576 AKRSDSGKYCVVVENSTGSRKGFCQVNVVDRPGPPVGPVSFDEVTKDYMVISWKPPLDDG 10635
Query: 1563 AVTVRYYRITYGETGGN--SPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDS-P 1619
+ Y I E G + PV T +K+T +S L G DY ++A G S P
Sbjct: 10636 GSKITNYIIEKKEVGKDVWMPV---TSASAKTTCKVSKLLEGKDYIFRIHAENLYGISDP 10692
Query: 1620 ASSKPISINYRTEI-DKPSQMQVTDVQDNSISVKWLP---SSSPVTGY---RVTTTPKNG 1672
S + R + D P Q VT+V +S V W P+T Y + T K
Sbjct: 10693 LVSDSMKAKDRFRVPDAPDQPIVTEVTKDSALVTWNKPHDGGKPITNYILEKRETMSKRW 10752
Query: 1673 PGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQN------PSGESQPL-VQTAVTNIDR 1725
TK T+ + L +Y V A+N PS S+P+ + +
Sbjct: 10753 ARVTKDPIH--PYTKFRVPDLLEGCQYEFRVSAENEIGIGDPSPPSKPVFAKDPIAKPSP 10810
Query: 1726 PKGLAFTDVDVDSIKIAWESPQ----GQVSRYRVTYSSPEDGI-HELFPAPDGEEDTA-E 1779
P D +S+ + W+ P+ ++ Y V Y D P+ +T +
Sbjct: 10811 PVNPEAIDTTCNSVDLTWQPPRHDGGSKILGYIVEYQKVGDEEWRRANHTPESCPETKYK 10870
Query: 1780 LQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTS-LSAQWTPPNV 1838
+ GLR G Y V+A++ ES P +P P +K P L A
Sbjct: 10871 VTGLRDGQTYKFRVLAVNAAGESDP------AHVPEPVLVKDRLEPPELILDANMAREQH 10924
Query: 1839 QLTGYRVRVT------PKEKTGPMKEINLAPDSSSVVVSGLMVATKYEV--------SVY 1884
G +R++ P K KE AP + + V+ V +K E+ +Y
Sbjct: 10925 IKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARIDVTP--VGSKLEIRNAAHEDGGIY 10982
Query: 1885 AL--KDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTE----TITGFQVD 1938
+L ++ S+ V L+ PPR V++ + + ++W+ + IT + V+
Sbjct: 10983 SLTVENPAGSKTVSVKVLVLDKPGPPRDLEVSEIRKDSCYLTWKEPLDDGGSVITNYVVE 11042
Query: 1939 A--VPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPV-------VID 1989
V + +P+ T K +S+ L G Y + N R V +D
Sbjct: 11043 RRDVASAQWSPLSATSKK--KSHFAKHLNEGNQYLFRVAAENQYGRGPFVETPKPIKALD 11100
Query: 1990 ASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREVVPRPRPG 2045
P +L + + + W P + ITGY+++Y++ G+ ++ +
Sbjct: 11101 PLHPPGPPKDLHHVDVDKTEVSLVWNKPDRDGGSPITGYLVEYQEEGT--QDWIKFKTVT 11158
Query: 2046 VTEATITGLEPGTEYTIYVIALKNNQKSEPLIG 2078
E +TGL+ G Y V K+E ++G
Sbjct: 11159 NLECVVTGLQQGKTYRFRV-------KAENIVG 11184
Score = 95.1 bits (235), Expect = 7e-19
Identities = 312/1572 (19%), Positives = 569/1572 (36%), Gaps = 228/1572 (14%)
Query: 616 ITETPSQPNSHPIQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLK 672
+T T S + W P+ S + Y++ +PK + +W N+ + GL
Sbjct: 17914 VTLTDVSQTSASLMWEKPEHDGGSRVLGYVVEMQPKGTE-KWSIVAESKVCNA-VVTGLS 17971
Query: 673 PGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETT---PFSP--LVATSES 727
G Y+ ++ + + G + PV + +T + + PF+ + A +
Sbjct: 17972 SGQEYQFRVKAYNEKGKSD-------PRVLGVPVIAKDLTIQPSLKLPFNTYSIQAGEDL 18024
Query: 728 VTEITASSFV---VSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGR 784
EI +SWV + + + +++ TATS + + G
Sbjct: 18025 KIEIPVIGRPRPNISWVKDGEPLK-------------QTTRVNVEETATST-VLHIKEGN 18070
Query: 785 KYIVNVYQISED---GEQSLILSTSQTTAPDAPPDPT-VDQVDDTSIVVRWSRPQ----A 836
K Y ++ G + LS P P P D+V +V+ W P
Sbjct: 18071 KDDFGKYTVTATNSAGTATENLSVIVLEKPGPPVGPVRFDEVSADFVVISWEPPAYTGGC 18130
Query: 837 PITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQ 896
I+ Y + + + ++ ++ ++ L+ G +Y I+A +S P+ +
Sbjct: 18131 QISNYIVEKRDTTTTTWHMVSATVARTTIKITKLKTGTEYQFRIFAENRYGKSAPLDSKA 18190
Query: 897 ETTGTPRSDTVPSPRDLQFV-EVTDVKVTIMWTPPES----AVTGYRVDVIPVN-LPGEH 950
P + P P FV ++ ++ + W P + + GY ++ N +
Sbjct: 18191 VIVQYPFKE--PGPPGTPFVTSISKDQMLVQWHEPVNDGGTKIIGYHLEQKEKNSILWVK 18248
Query: 951 GQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQT----TKLDAPTNLQFV 1006
+ PI F + TGL G+ Y FKV A + KP + D P + +
Sbjct: 18249 LNKTPIQDTKF-KTTGLDEGLEYEFKVSAENIVGIGKPSKVSECFVARDPCDPPGRPEAI 18307
Query: 1007 NETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSV-SKYPLRNLQPASE 1061
T + V ++W P ++ITGY + G+ + + + +++ + L
Sbjct: 18308 VITRNNVTLKWKKPAYDGGSKITGYIVEKKDLPDGRWMKASFTNVLETEFTVSGLVEDQR 18367
Query: 1062 YTVSLVA--IKGNQESPK-ATGVFTTLQ----PGSSIPPYNTEVT-----ETTIV---IT 1106
Y ++A GN P ++G T P +S+ P +V ET ++ I
Sbjct: 18368 YEFRVIARNAAGNFSEPSDSSGAITARDEIDAPNASLDPKYKDVIVVHAGETFVLEADIR 18427
Query: 1107 WTPAPRIGFKLGVRPSQGGEAPREVTS--DSGSIVVSGL--TPGVEYVYTIQVLRDGQER 1162
P P + + + + A E+ S ++VV T G +Y+ +++ G +
Sbjct: 18428 GKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQYI--LKLSNVGGTK 18485
Query: 1163 DAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWE---RSTTPDITGYRITTTPTNGQQGN 1219
PI KV+ PP ++W + +I+ Y I T+
Sbjct: 18486 SIPITVKVLDRPGPPEGPLKVTGVTAEKCYLAWNPPLQDGGANISHYIIEKRETSRLSWT 18545
Query: 1220 SLEEVVHADQSSCTFDNLSPGLEY-----NVSVYTVKDDKESVPIS---------DTIIP 1265
+ V A T L PG EY V+ Y + + ES P++ P
Sbjct: 18546 QVSTEVQALNYKVT--KLLPGNEYIFRVMAVNKYGIGEPLESGPVTACNPYKPPGPPSTP 18603
Query: 1266 EVPQLTDLSFV-----DITDSSI-------------GLRWTPLNSSTIIGYRITVVAAGE 1307
EV +T S V + D G+RWT N T+ R+ V E
Sbjct: 18604 EVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDKEGVRWTKCNKKTLTDLRLRVTGLTE 18663
Query: 1308 GIPI-FEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAVPPPTDLRF 1366
G F +++ G + EP + Y G PP++ +
Sbjct: 18664 GHSYEFRVAAENAAGVGEPS--EPSVFYRACDALYPPG---------------PPSNPKV 18706
Query: 1367 TNIGPDTMRVTWAPP---PSIDLTNFLVRYSPVKNEE-DVAELSISPSDNAVVLTNLLPG 1422
T+ ++ + W+ P + ++V +E +T L
Sbjct: 18707 TDTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAADEWTTCTPPTGLQGKQFTVTKLKEN 18766
Query: 1423 TEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGY-RI 1481
TEY + ++ + P ++ A+ V + AT+ + I
Sbjct: 18767 TEYNFRICAINSEGVGEPATLPGSVVAQERIEPPEIELDADLRKVVVLRASATLRLFVTI 18826
Query: 1482 RHHPEHFSGRPREDRVPHSRNSITLT---------NLTPGTEYVVSIVALNGREESPLLI 1532
+ PE + + + R I +T N+T ++ N +
Sbjct: 18827 KGRPEPEVKWEKAEGILTDRAQIEVTSSFTMLVIDNVTRFDSGRYNLTLENNSGSKTAFV 18886
Query: 1533 GQQSTVS-DVPRDLEVVAATPTSLLISWDAPAVT----VRYYRITYGETGGNSPVQEFTV 1587
+ S P +L + S+ +SW+ P + + Y + ET + T
Sbjct: 18887 NVRVLDSPSAPVNLTIREVKKDSVTLSWEPPLIDGGAKITNYIVEKRETTRKA-YATITN 18945
Query: 1588 PGSKSTATISGLKPGVDYTITVYAVT--GRGDSPASSKPISINYRTEIDKPSQMQVTDVQ 1645
+K+T I L+ G Y V A G G +++P+ ++ P ++ + DV
Sbjct: 18946 NCTKTTFRIENLQEGCSYYFRVLASNEYGIGLPAETTEPVKVSEPPL--PPGRVTLVDVT 19003
Query: 1646 DNSISVKW-LPSS---SPVTGYRVTTTPKNGPGPTKTKTAGPDQT-EMTIEGLQPTVEYV 1700
N+ ++KW P S S +TGY V K G K T +T E TI GL EYV
Sbjct: 19004 RNTATIKWEKPESDGGSKITGYVVEMQTK---GSEKWSTCTQVKTLEATISGLTAGEEYV 19060
Query: 1701 VSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVD-SIKIAWESPQGQVSRYRVTYSS 1759
V A N G S P Q V I R D+++ S+++ + + + +R ++
Sbjct: 19061 FRVAAVNEKGRSDPR-QLGVPVIAR-------DIEIKPSVELPFHTFNVK-AREQLKIDV 19111
Query: 1760 PEDGIHELFP--APDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQ-------- 1809
P G + DG+ E + S TV+ +++ + S+ +GT
Sbjct: 19112 PFKGRPQATVNWRKDGQT-LKETTRVNVSSSKTVTSLSIKE--ASKEDVGTYELCVSNSA 19168
Query: 1810 -STAIPA----------PTDLKFTQVTPTSLSAQWTPPNV----QLTGYRVRVTPKEKTG 1854
S +P P ++ +V+ S++ W PP Q++ Y V KE T
Sbjct: 19169 GSITVPITIIVLDRPGPPGPIRIDEVSCDSITISWNPPEYDGGCQISNYIVE--KKETTS 19226
Query: 1855 PMKEI-NLAPDSSSVVVSGLMVATKYEVSVYAL----KDTLTSRPAQGVVTTLENVSPPR 1909
I + A +S+ + L ++Y+ V A K + + A PP
Sbjct: 19227 TTWHIVSQAVARTSIKIVRLTTGSEYQFRVCAENRYGKSSYSESSAVVAEYPFSPPGPPG 19286
Query: 1910 RARVTDATETTITISWRTKT----ETITGFQVDAVPANG--QTPIQRTIKPDVRSYTITG 1963
+V AT++T+ ++W+ + G+ ++ + + + + D + ++G
Sbjct: 19287 TPKVVHATKSTMLVTWQVPVNDGGSRVIGYHLEYKERSSILWSKANKILIADTQ-MKVSG 19345
Query: 1964 LQPGTDYKIYLYTLN----DNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPR- 2018
L G Y+ +Y N S + A D P T S+ + W P
Sbjct: 19346 LDEGLMYEYRVYAENIAGIGKCSKSCEPVPARDPCDPPGQPEVTNITRKSVSLKWSKPHY 19405
Query: 2019 ---ARITGYIIK 2027
A+ITGYI++
Sbjct: 19406 DGGAKITGYIVE 19417
Score = 94.7 bits (234), Expect = 1e-18
Identities = 315/1607 (19%), Positives = 572/1607 (35%), Gaps = 282/1607 (17%)
Query: 628 IQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISI 684
+ W P+ + I Y++ K W + + GL G Y ++ ++
Sbjct: 7697 LNWTKPEHDGGAKIESYVIEML-KTGTDEWVRVAEGVPTTQHLLPGLMEGQEYSFRVRAV 7755
Query: 685 QQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSAS 744
+ G E + S+ V + P V IT ++ + W +
Sbjct: 7756 NKAGESEPSE------------PSDPVLCREKLYPPSPPRWLEVINITKNTADLKW-TVP 7802
Query: 745 DTVSGFRVEYELSEEGDEP----QYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGE-- 798
+ G + + E+ D Q +D T + L G Y+ V + G+
Sbjct: 7803 EKDGGSPITNYIVEKRDVRRKGWQTVDTTVKDTKCTVTPLTEGSLYVFRVAAENAIGQSD 7862
Query: 799 ----QSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ----APITGYRIVYSPSVE 850
+ +L+ T P P V V + ++W P+ PI Y I +
Sbjct: 7863 YTEIEDSVLAKDTFTTPGPPYALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKERL- 7921
Query: 851 GSSTELNLPETAN---SVTLSDLQPGVQYNITIYAVEEN-----QESTPVVIQQETTGTP 902
+ + +TA + ++D+ G + + A E E T ++ ++ T P
Sbjct: 7922 -GTRWVKAGKTAGPDCNFRVTDVIEGTEVQFQVRAENEAGVGHPSEPTEILSIEDPTSPP 7980
Query: 903 RSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPVNLPGEHGQRL---P 955
P DL + + I W PPE S + GY V++ PV E R+ P
Sbjct: 7981 SP-----PLDLHVTDAGRKHIAIAWKPPEKNGGSPIIGYHVEMCPVGT--EKWMRVNSRP 8033
Query: 956 ISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLV 1015
I F G+ P Y +V AV+ S+P + P ++ ++V
Sbjct: 8034 IKDLKFKVEEGVVPDKEYVLRVRAVNAIGVSEPSEISENVVAKDPDCKPTIDLETHDIIV 8093
Query: 1016 RWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPL-RNLQPASEYTVSLVAIKGNQE 1074
I G +L++ + R P P+VS + + ++ + T+ I + E
Sbjct: 8094 --------IEGEKLSIPVPFRAVPV-----PTVSWHKDGKEVKASDRLTMKNDHISAHLE 8140
Query: 1075 SPKAT----GVFT-TLQP--GSSIPPYN---------------TEVTETTIVITWTP--- 1109
PK+ G++T TL+ GS+ N +++T+++ +TW P
Sbjct: 8141 VPKSVRADAGIYTITLENKLGSATASINVKVIGLPGPCKDIKASDITKSSCKLTWEPPEF 8200
Query: 1110 ---APRIGFKLGVRPSQGGEAPREVTSDSGSI--VVSGLTPGVEYVYTIQVLRD-GQERD 1163
P + + L R + G V S + V L P EY + ++ + G
Sbjct: 8201 DGGTPILHYVLERREA-GRRTYIPVMSGENKLSWTVKDLIPNGEYFFRVKAVNKVGGGEY 8259
Query: 1164 APIVNKVVT-----PLSPPTNLHLEANPDTGVLTVSWERSTTPD---ITGYRITTTPTNG 1215
+ N V+ P PP ++ + NP +T++W+ I GY I
Sbjct: 8260 IELKNPVIAQDPKQPPDPPVDVEVH-NPTAEAMTITWKPPLYDGGSKIMGYIIEKIAKGE 8318
Query: 1216 QQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYT-----VKDDKESVPISDTIIP-EVPQ 1269
++ E + + T L G EY V + + + P + + P + P+
Sbjct: 8319 ERWKRCNEHL-VPILTYTAKGLEEGKEYQFRVRAENAAGISEPSRATPPTKAVDPIDAPK 8377
Query: 1270 LTDLSFVDIT-------DSSIG------LRWTPLNSSTIIGYRITVVAA-------GEGI 1309
+ + +++ D+SI + W + + I+ I AA GE +
Sbjct: 8378 VILRTSLEVKRGDEIALDASISGSPYPTITWIK-DENVIVPEEIKKRAAPLVRRRKGE-V 8435
Query: 1310 PIFEDFVDSSVGYYTVTGLEPGI-----------DYDISVITLIN--GGESAPTTLTQQT 1356
E FV ++ + G D+ + +I + N G AP T++
Sbjct: 8436 QEEEPFVLPLTQRLSIDNSKKGESQLRVRDSLRPDHGLYMIKVENDHGIAKAPCTVSVLD 8495
Query: 1357 AVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVL 1416
PP + F +I ++ W PP D + ++ Y+ K ++ P +V+
Sbjct: 8496 TPGPPINFVFEDIRKTSVLCKWEPPLD-DGGSEIINYTLEKKDK------TKPDSEWIVV 8548
Query: 1417 TNLLPGTEYVVSVSSVYEQHE------------------STPLRGRQKTG-LDSPTGIDF 1457
T+ L +Y SV+ + E E S PL + G D+P
Sbjct: 8549 TSTLRHCKY--SVTKLIEGKEYLFRVRAENRFGPGPPCVSKPLVAKDPFGPPDAPDKPIV 8606
Query: 1458 SDITANSFTVHWIAPR---ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTE 1514
D+T+NS V W P+ + I GY + + + R ++ + + L G
Sbjct: 8607 EDVTSNSMLVKWNEPKDNGSPILGYWLEKREVNSTHWSRVNKSLLNALKANVDGLLEGLT 8666
Query: 1515 YVVSIVALN----GREESPLLIGQQSTVSD--------VPRDLEVVAATPTSLLISWDAP 1562
YV + A N G+ P T D +PR V + T++ + W+ P
Sbjct: 8667 YVFRVCAENAAGPGKFSPP---SDPKTAHDPISPPGPPIPR---VTDTSSTTIELEWEPP 8720
Query: 1563 AVT----VRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDS 1618
A + Y + G N + T+ ++ G DY + V AV G+
Sbjct: 8721 AFNGGGEIVGYFVDKQLVGTNEWSRCTEKMIKVRQYTVKEIREGADYKLRVSAVNAAGEG 8780
Query: 1619 -PASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTK 1677
P ++P+++ E +P +++ +SVK R+ P PTK
Sbjct: 8781 PPGETQPVTV---AEPQEPPAVEL------DVSVKGGIQIMAGKTLRIPAVVTGRPVPTK 8831
Query: 1678 --TKTAGP-DQTEMTIEGLQPTVEYVVS-----------VYAQNPSGESQPLVQTAVTNI 1723
TK G D+ + I+ + E ++ + A N G + V ++
Sbjct: 8832 VWTKEEGELDKDRVVIDNVGTKSELIIKDALRKDHGRYVITATNSCGSKFAAARVEVFDV 8891
Query: 1724 DRP-KGLAFTDVDVDSIKIAWESPQ----GQVSRYRVTYSSPEDGIHELFPAPDGEEDTA 1778
P L + + W P+ +++ + + + +H + E
Sbjct: 8892 PGPVLDLKPVVTNRKMCLLNWSDPEDDGGSEITGFIIERKDAK--MHTWRQPIETERSKC 8949
Query: 1779 ELQGLRPGSEYTVSVVALH-----DDMESQPLIGTQSTAIP-APTDLKFTQVTPTSLSAQ 1832
++ GL G EY V+A + +E P++ P +P L +T+ T ++++
Sbjct: 8950 DITGLLEGQEYKFRVIAKNKFGCGPPVEIGPILAVDPLGPPTSPERLTYTERTKSTITLD 9009
Query: 1833 WTPPNVQ----LTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKD 1888
W P + GY + +K + ++S +V L YE V A+ +
Sbjct: 9010 WKEPRSNGGSPIQGYIIEKRRHDKPDFERVNKRLCPTTSFLVENLDEHQMYEFRVKAVNE 9069
Query: 1889 TLTSRPA--QGVVTTLENVSPPRRARVTDATETTIT-------------------ISWRT 1927
S P+ VV + V P + R++ +T I W +
Sbjct: 9070 IGESEPSLPLNVVIQDDEVPPTIKLRLSVRGDTIKVKAGEPVHIPADVTGLPMPKIEW-S 9128
Query: 1928 KTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVV 1987
K ET+ DA+ + + K ++ GT YT+ + R V
Sbjct: 9129 KNETVIEKPTDALQITKEEVSRSEAKTELSIPKAVREDKGT------YTVTASNRLGSVF 9182
Query: 1988 IDASTAI-DAPSNLRFLATT---PNSLLVSWQPP----RARITGYII 2026
+ + D PS R LA T S ++W P + IT Y+I
Sbjct: 9183 RNVHVEVYDRPSPPRNLAVTDIKAESCYLTWDAPLDNGGSEITHYVI 9229
Score = 94.0 bits (232), Expect = 2e-18
Identities = 154/662 (23%), Positives = 253/662 (38%), Gaps = 93/662 (14%)
Query: 1538 VSDVP---RDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTA 1594
V DVP R+LEV + ++W+ P I Y + + + + ++ +
Sbjct: 6781 VIDVPGPVRNLEVTETFDGEVSLAWEEPLTDGGSKIIGYVVERRDIKRKTWVLATDRAES 6840
Query: 1595 ---TISGL-KPGVDYTITVYAVT--GRGDSPASSKPISINYRTEIDKPS-QMQVTDVQDN 1647
T++GL K GV+Y V A G G+ + P+ + ++ P + +TDV
Sbjct: 6841 CEFTVTGLQKGGVEYLFRVSARNRVGTGEPVETDNPVEARSKYDVPGPPLNVTITDVNRF 6900
Query: 1648 SISVKWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSV 1703
+S+ W P + +T Y + K T + T+ + EY V
Sbjct: 6901 GVSLTWEPPEYDGGAEITNYVIELRDKTSIRWDTAMTVRAEDLSATVTDVVEGQEYSFRV 6960
Query: 1704 YAQNPSGESQPLVQTAVTN----IDRPK---GLAFTDVDVDSIKIAWESPQGQVSRYRVT 1756
AQN G +P T I+RP L +D S+++ WE P +
Sbjct: 6961 RAQNRIGVGKPSAATPFVKVADPIERPSPPVNLTSSDQTQSSVQLKWEPPLKDGGSPILG 7020
Query: 1757 Y--SSPEDGIH-------ELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIG 1807
Y E+G +L P E T ++ GL G++Y V A + S P
Sbjct: 7021 YIIERCEEGKDNWIRCNMKLVP-----ELTYKVTGLEKGNKYLYRVSAENKAGVSDP--- 7072
Query: 1808 TQSTAIPAPTDLKFTQVTPT-SLSA-----QWTPPN-----VQLTGY-RVRVT-----PK 1850
+ I P V PT LSA + PN V TGY R T
Sbjct: 7073 ---SEILGPLTADDAFVEPTMDLSAFKDGLEVIVPNPITILVPSTGYPRPTATWCFGDKV 7129
Query: 1851 EKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGV--VTTLENVSPP 1908
+TG ++ + +V+S + + + +Y LK + G V + S P
Sbjct: 7130 LETGDRVKMKTLSAYAELVISP---SERSDKGIYTLKLENRVKTISGEIDVNVIARPSAP 7186
Query: 1909 RRARVTDATETTITISWRTKTET----ITGFQVDAVPANGQTPIQRTIKPDVRSYTITGL 1964
+ + D T+ ++ ++W + +TG+ V+ + +T + +T+ L
Sbjct: 7187 KELKFGDITKDSVHLTWEPPDDDGGSPLTGYVVEKREVSRKTWTKVMDFVTDLEFTVPDL 7246
Query: 1965 QPGTDYKIYLYTLNDNARSSPVVIDA-------STAIDAPSNLRFLATTPNSLLVSWQPP 2017
G +Y + N P +D +T D P N+++ T NS+ ++W PP
Sbjct: 7247 VQGKEYLFKVCARNKCGPGEPAYVDEPVNMSTPATVPDPPENVKWRDRTANSIFLTWDPP 7306
Query: 2018 R----ARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKS 2073
+ +RI GYI++ GS P T+ +TGLE G Y V AL S
Sbjct: 7307 KNDGGSRIKGYIVERCPRGSDKWVACGEP-VAETKMEVTGLEEGKWYAYRVKALNRQGAS 7365
Query: 2074 EPLIGRKKTDELPQLVTLPHPNLHGPEILDVPSTVQKTPFVTHPGYDTGNGIQLPGTSGQ 2133
+P + T+E+ + T P + LDV T G I+LP T
Sbjct: 7366 KP---SRPTEEIQAVDTQEAPEI----FLDVKLLAGLT-------VKAGTKIELPATVTG 7411
Query: 2134 QP 2135
+P
Sbjct: 7412 KP 7413
Score = 90.5 bits (223), Expect = 2e-17
Identities = 354/1666 (21%), Positives = 582/1666 (34%), Gaps = 229/1666 (13%)
Query: 624 NSHPIQWNAPQ---PSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKG--LKPGVVYE 678
+S + W P+ S I+ YI+ R S W+ + + TIK LK G Y+
Sbjct: 15951 DSITLSWGPPKYDGGSSINNYIVEKRD-TSTTTWQ--IVSATVARTTIKACRLKTGCEYQ 16007
Query: 679 GQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVV 738
++ + +YG + T V P +P+V S + S V
Sbjct: 16008 FRIAAENRYGKSTYLNSEPTVAQYPFKVPG-------PPGTPVVTLS------SRDSMEV 16054
Query: 739 SWVSASDTVSGFRVEYELS-EEGDEPQYLDL---PSTATSVNIPDLLPGRKYI--VNVYQ 792
W + Y L +E + ++ L P T L G +Y V+
Sbjct: 16055 QWNEPISDGGSRVIGYHLERKERNSILWVKLNKTPIPQTKFKTTGLEEGVEYEFRVSAEN 16114
Query: 793 ISEDGEQSLILSTSQTTAPDAPPD-PTVDQVDDTSIVVRWSRPQ----APITGYRIVYSP 847
I G+ S + P PP P V S+ ++W +P + ITGY +
Sbjct: 16115 IVGIGKPSKVSECYVARDPCDPPGRPEAIIVTRNSVTLQWKKPTYDGGSKITGYIVEKKE 16174
Query: 848 SVEG---SSTELNLPETANSVTLSDLQPGVQYNITIYA------VEENQESTPVVIQQET 898
EG ++ N+ +T VT L +Y + A E EST + ++
Sbjct: 16175 LPEGRWMKASFTNIIDTHFEVT--GLVEDHRYEFRVIARNAAGVFSEPSESTGAITARDE 16232
Query: 899 TGTPRSDTVPSPRDLQFVEVTD---VKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLP 955
PR P +D V + V I P + + I + + RL
Sbjct: 16233 VDPPRISMDPKYKDTIVVHAGESFKVDADIYGKPIPT------IQWIKGDQELSNTARLE 16286
Query: 956 ISRNTFAEVTGLSPGV-----TYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNE-T 1009
I FA + V Y K V+ G S + + + P ++ T
Sbjct: 16287 IKSTDFATSLSVKDAVRVDSGNYILKAKNVA-GERSVTVNVKVLDRPGPPEGPVVISGVT 16345
Query: 1010 DSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVS 1065
+ W PP + I Y + T R + + L +EYT
Sbjct: 16346 AEKCTLAWKPPLQDGGSDIINYIVERRETSRLVWTVVDANVQTLSCKVTKLLEGNEYTFR 16405
Query: 1066 LVAIKGNQ-----ESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWT-PAPR-----IG 1114
++A+ ES + P + P T VT+ ++++ W PA +G
Sbjct: 16406 IMAVNKYGVGEPLESEPVVAKNPFVVPDAPKAPEVTTVTKDSMIVVWERPASDGGSEILG 16465
Query: 1115 FKLGVRPSQGGEAPREVTSDSGSIV--VSGLTPGVEYVYTIQVLRD-GQERDAP--IVNK 1169
+ L R +G R G + V+GL +Y + + G +P K
Sbjct: 16466 YVLEKRDKEGIRWTRCHKRLIGELRLRVTGLIENHDYEFRVSAENAAGLSEPSPPSAYQK 16525
Query: 1170 VVTPL---SPPTNLHLEANPDTGVLTVSWERSTTP---DITGYRITTTPTNGQQGNSLEE 1223
P+ PP N + + V +SW + +I GY + + +
Sbjct: 16526 ACDPIYKPGPPNNPKVIDITRSSVF-LSWSKPIYDGGCEIQGYIVEKCDVSVGEWTMCTP 16584
Query: 1224 VVHADQSSCTFDNLSPGLEYNVSVYTVKD----DKESVPISDTIIPEVPQLTDLSFVDIT 1279
++++ + L EYN + + + VP I+ E + D+
Sbjct: 16585 PTGINKTNIEVEKLLEKHEYNFRICAINKAGVGEHADVP-GPIIVEEKLEAPDI------ 16637
Query: 1280 DSSIGLRWTPLNSSTIIGYRITVVAAGEGIP----------IFEDFVDSSVGYYTVTGLE 1329
D + LR +N R+ V G P I + + +T L+
Sbjct: 16638 DLDLELRKI-INIRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTSSFTSLVLD 16696
Query: 1330 PGIDYDISVITLI----NGGESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAPPPSID 1385
YD TL +G +SA T+ PP +L+ T I D++ +TW PP +D
Sbjct: 16697 NVNRYDSGKYTLTLENSSGTKSAFVTVRVLDTPSPPVNLKVTEITKDSVSITW-EPPLLD 16755
Query: 1386 LTNFLVRYSPVKNE---EDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLR 1442
+ + Y K E + A + + N+ + L G Y V++ E P +
Sbjct: 16756 GGSKIKNYIVEKREATRKSYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAENEYGIGLPAQ 16815
Query: 1443 GRQKTGL----DSPTGIDFSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPRE 1494
+ P I D+T NS ++ W P + I Y + +H
Sbjct: 16816 TADPIKVAEVPQPPGKITVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKHSEKWSEC 16875
Query: 1495 DRVPHSRNSITLTNLTPGTEYVVSIVALNGREES-PLLIGQQSTVSDVPRDLEVVAA-TP 1552
RV + +TNLT G EY+ +VA+N + S P + D+ + +V A +
Sbjct: 16876 ARVKSLQ--AVITNLTQGEEYLFRVVAVNEKGRSDPRSLAVPIVAKDLVIEPDVKPAFSS 16933
Query: 1553 TSLLISWD----APAVTVRYYRITYGETGGNSPVQEFT---VPGSKSTATIS----GLKP 1601
S+ + D P IT+ + G P+++ T V S T+S
Sbjct: 16934 YSVQVGQDLKIEVPISGRPKPTITWTKDG--LPLKQTTRINVTDSLDLTTLSIKETHKDD 16991
Query: 1602 GVDYTITVYAVTGRGDSPASSKPISINYRTEIDKP----SQMQVTDVQDNSISVKWLP-- 1655
G Y ITV V G+ K SI T +DKP ++ DV SI++ W P
Sbjct: 16992 GGQYGITVANVVGQ-------KTASIEIVT-LDKPDPPKGPVKFDDVSAESITLSWNPPL 17043
Query: 1656 --SSSPVTGYRV-----TTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNP 1708
+T Y V TTT + T +T + + L+ EY ++A+N
Sbjct: 17044 YTGGCQITNYIVQKRDTTTTVWDVVSATVARTT------LKVTKLKTGTEYQFRIFAENR 17097
Query: 1709 SG-----ESQPLVQTAVTNIDRPKGLAF-TDVDVDSIKIAWESPQGQVSRYRVTYSSPED 1762
G ES P+V P G F T + DS+ I W P + Y
Sbjct: 17098 YGQSFALESDPIVAQYPYKEPGPPGTPFATAISKDSMVIQWHEPVNNGGSPVIGYHLERK 17157
Query: 1763 GIHELFPAPDGE---EDTA-ELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTD 1818
+ + + DT + Q L G EY V A + + ++ P D
Sbjct: 17158 ERNSILWTKVNKTIIHDTQFKAQNLEEGIEYEFRVYAENIVGVGKASKNSECYVARDPCD 17217
Query: 1819 LKFT----QVTPTSLSAQWTPP----NVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVV 1870
T V ++ QWT P +TGY V MK + V
Sbjct: 17218 PPGTPEPIMVKRNEITLQWTKPVYDGGSMITGYIVEKRDLPDGRWMKASFTNVIETQFTV 17277
Query: 1871 SGLMVATKYEVSVYALKDT-LTSRPAQ--GVVTTLENVSPPRRARVTDATETTITISWRT 1927
SGL +YE V A S+P+ G +T + V PR + +T + + T
Sbjct: 17278 SGLTEDQRYEFRVIAKNAAGAISKPSDSTGPITAKDEVELPRISMDPKFRDTIVVNAGET 17337
Query: 1928 KTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQ-PGTDYKIYL------------ 1974
F+++A P ++ D + TD+K L
Sbjct: 17338 -------FRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRIDGGQ 17390
Query: 1975 YTLNDN----ARSSPV---VIDASTAIDAPSNLRFLATTPNSLLVSWQPP----RARITG 2023
Y L + ++S PV V+D + P ++ T ++W PP + I+
Sbjct: 17391 YILRASNVAGSKSFPVNVKVLDRPGPPEGP--VQVTGVTSEKCSLTWSPPLQDGGSDISH 17448
Query: 2024 YIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTD 2083
Y+++ ++ S V +T L G EY ++A+ EPL +
Sbjct: 17449 YVVE-KRETSRLAWTVVASEVVTNSLKVTKLLEGNEYVFRIMAVNKYGVGEPL------E 17501
Query: 2084 ELPQLVTLPHPNLHGPEILDVPSTVQKTPFVTHPGYDTGNGIQLPG 2129
P L+ P P+ L+V + + + V D+ G ++ G
Sbjct: 17502 SAPVLMKNPFVLPGPPKSLEVTNIAKDSMTVCWNRPDSDGGSEIIG 17547
Score = 86.7 bits (213), Expect = 3e-16
Identities = 349/1678 (20%), Positives = 599/1678 (35%), Gaps = 279/1678 (16%)
Query: 628 IQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISI 684
+ W+ P+ S I+ +I+ R + W++ I + I GL G Y+ ++I+
Sbjct: 8910 LNWSDPEDDGGSEITGFIIE-RKDAKMHTWRQP-IETERSKCDITGLLEGQEYKFRVIAK 8967
Query: 685 QQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWV--- 741
++G PV + P + TE T S+ + W
Sbjct: 8968 NKFG-------------CGPPVEIGPILAVDPLGPPTSPERLTYTERTKSTITLDWKEPR 9014
Query: 742 -SASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQS 800
+ + G+ +E ++ D + TS + +L + Y V ++E GE
Sbjct: 9015 SNGGSPIQGYIIEKRRHDKPDFERVNKRLCPTTSFLVENLDEHQMYEFRVKAVNEIGESE 9074
Query: 801 LILSTSQTTAPDAPPDPTVD---QVDDTSIVVRWSRP---QAPITGYRIVYSPSVEGSST 854
L + D P PT+ V +I V+ P A +TG + P +E S
Sbjct: 9075 PSLPLNVVIQDDEVP-PTIKLRLSVRGDTIKVKAGEPVHIPADVTGLPM---PKIEWSKN 9130
Query: 855 E--LNLPETANSVTLSDLQPG-VQYNITI-YAVEENQESTPVVIQQETTGTPRS------ 904
E + P A +T ++ + ++I AV E++ + V R+
Sbjct: 9131 ETVIEKPTDALQITKEEVSRSEAKTELSIPKAVREDKGTYTVTASNRLGSVFRNVHVEVY 9190
Query: 905 DTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPGEHGQRLPISRNT 960
D PR+L ++ + W P S +T Y +D + + + NT
Sbjct: 9191 DRPSPPRNLAVTDIKAESCYLTWDAPLDNGGSEITHYVIDKRDASRKKAEWEEVT---NT 9247
Query: 961 FAE----VTGLSPGVTYYFKV-----FAVSHGRESKPLTAQQTTKLDAPTNL-QFVNETD 1010
E + L P Y F+V + +S +S + Q +L P + + T
Sbjct: 9248 AVEKRYGIWKLIPNGQYEFRVRAVNKYGISDECKSDKVVIQDPYRLPGPPGKPKVLARTK 9307
Query: 1011 STVLVRWTPPR----AQITGYRLTVGLTRRGQPRQY----------NVGPSVSKYPLRNL 1056
++LV WTPP + ITGY L +R + Y VG ++ + L
Sbjct: 9308 GSMLVSWTPPLDNGGSPITGY----WLEKREEGSPYWSRVSRAPITKVGLKGVEFNVPRL 9363
Query: 1057 QPASEYTVSLVAIKG-------NQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTP 1109
+Y +AI P+ G PG P + T+++I + W P
Sbjct: 9364 LEGVKYQFRAMAINAAGIGPPSEPSDPEVAGD-PIFPPGPPSCPEVKDKTKSSISLGWKP 9422
Query: 1110 APRIGFKLGVRPSQGG--EAPREVTSDSGSI------------VVSGLTPGVEYVYTIQV 1155
K G P +G E E T+D + VV L +Y + ++
Sbjct: 9423 PA----KDGGSPIKGYIVEMQEEGTTDWKRVNEPDKLITTCECVVPNLKELRKYRFRVKA 9478
Query: 1156 LRD-GQERDAPIVNKV-VTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPT 1213
+ + G+ + ++ T + + ++ ++ + + P + R T +
Sbjct: 9479 VNEAGESEPSDTTGEIPATDIQEEPEVFIDIGAQDCLVCKAGSQIRIPAVIKGRPTPKSS 9538
Query: 1214 ---NGQQGNSLEEVVH---ADQSSCTFDNLSPGL----------EYNVSVYTVKDDKES- 1256
+G+ ++++ VH D T +N S + +Y+++ K +
Sbjct: 9539 WEFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECKRSHTGKYSITAKNKAGQKTAN 9598
Query: 1257 --VPISDTIIPEVPQLTDLSFVDITDSSIGLRWTPLNSS---TIIGYRITVVAAGEGIPI 1311
V + D +P P+ DL DIT S L W + I GY I +G
Sbjct: 9599 CRVKVMD--VPGPPK--DLKVSDITRGSCRLSWKMPDDDGGDRIKGYVIEKRTI-DGKAW 9653
Query: 1312 FEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAV-------PPPTDL 1364
+ D + V L Y V G P Q+T PP L
Sbjct: 9654 TKVNPDCGSTTFVVPDLLSEQQYFFRVRAENRFGIGPPVETIQRTTARDPIYPPDPPIKL 9713
Query: 1365 RFTNIGPDTMRVTWAPPPS---IDLTNFLVR---YSPVK---------NEEDVAELSISP 1409
+ I +T+ ++W PP + +T+++V + P N+ DV EL +
Sbjct: 9714 KIGLITKNTVHLSWKPPKNDGGSPVTHYIVECLAWDPTGTKKEAWRQCNKRDVEELQFTV 9773
Query: 1410 SDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGL---DSPTGIDFSDI--TANS 1464
D L+ G EY V +V S P D P ID +
Sbjct: 9774 ED-------LVEGGEYEFRVKAVNAAGVSKPSATVGPCDCQRPDMPPSIDLKEFMEVEEG 9826
Query: 1465 FTVHWIA-----PRATITGYRIRH----------HPEHFSGRPREDR----VPHSRNSIT 1505
V+ +A P T+T ++ + H + +D +P SR S T
Sbjct: 9827 TNVNIVAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDT 9886
Query: 1506 LTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAP--- 1562
Y ++ V G + + ++ + + + +SW P
Sbjct: 9887 GL-------YTITAVNNLGTASKEMRLNVLGRPGPPVGPIKFESVSADQMTLSWFPPKDD 9939
Query: 1563 -AVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRG-DSPA 1620
+ Y I E + V + P + T TI L G +Y + A G P
Sbjct: 9940 GGSKITNYVIEKREANRKTWVHVSSEP-KECTYTIPKLLEGHEYVFRIMAQNKYGIGEPL 9998
Query: 1621 SSKPISI-NYRTEIDKPSQMQVTDVQDNSISVKW----LPSSSPVTGYRVT---TTPKN- 1671
S+P + N + P + V+ V NS++V W SPVTGY + TT K
Sbjct: 9999 DSEPETARNLFSVPGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPVTGYWLEMKDTTSKRW 10058
Query: 1672 ---GPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSG---ESQPLVQTAVTNIDR 1725
P K T G + GL +Y VYA N +G S P +
Sbjct: 10059 KRVNRDPIKAMTLG---VSYKVTGLIEGSDYQFRVYAINAAGVGPASLPSDPATARDPIA 10115
Query: 1726 PKGLAF---TDVDVDSIKIAWESPQ----GQVSRYRVTYSSPEDGIHELFPAPDGEEDTA 1778
P G F TD S + W P +V+ Y V Y E+G E D E
Sbjct: 10116 PPGPPFPKVTDWTKSSADLEWSPPLKDGGSKVTGYIVEYK--EEGKEEWEKGKDKEVRGT 10173
Query: 1779 EL--QGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPT-SLSAQWTP 1835
+L GL+ G+ Y V A++ +P G + I ++K V+P L A
Sbjct: 10174 KLVVTGLKEGAFYKFRVRAVNIAGIGEP--GEVTDVI----EMKDRLVSPDLQLDASVRD 10227
Query: 1836 PNVQLTGYRVRVT-------PKEKTGPMKEINLAPDSS--SVVVSGLMVATKYEVS---V 1883
V G +R+ P T M E L +++ + +S MV + S V
Sbjct: 10228 RIVVHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEATIETTAISSSMVIKNCQRSHQGV 10287
Query: 1884 YAL--KDTLTSRPAQGVVTTLENVSPPRRARVT-DATETTITISWRTKTET----ITGFQ 1936
Y+L K+ R +V L+ P + + T + ++W + + IT +
Sbjct: 10288 YSLLAKNEAGERKKTIIVDVLDVPGPVGTPFLAHNLTNESCKLTWFSPEDDGGSPITNYV 10347
Query: 1937 VDAVPANGQ--TPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLND-------NARSSPVV 1987
++ ++ + TP+ T+ ++ T+ GL G Y + N + V+
Sbjct: 10348 IEKRESDRRAWTPVTYTVTR--QNATVQGLIQGKAYFFRIAAENSIGMGPFVETSEALVI 10405
Query: 1988 IDASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREVVPRPR 2043
+ T + P +L T N++ ++W PP+ + I Y+++ G+ V
Sbjct: 10406 REPITVPERPEDLEVKEVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEKFHKVTNDN 10465
Query: 2044 PGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELPQLVT----LPHPNLH 2097
+ T+ GL+ G Y V A+ ++G+ K + +T L P LH
Sbjct: 10466 LLSRKYTVKGLKEGDTYEYRVSAVN-------IVGQGKPSFCTKPITCKDELAPPTLH 10516
Score = 86.7 bits (213), Expect = 3e-16
Identities = 320/1612 (19%), Positives = 550/1612 (34%), Gaps = 233/1612 (14%)
Query: 630 WNAPQPSH---ISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQ 686
W+ P+ IS Y++ R +S W E +Y L G+ Y+ ++ + +
Sbjct: 14875 WDPPENDGGVPISNYVVEMRQTDST-TWVELATTVIRTTYKATRLTTGLEYQFRVKAQNR 14933
Query: 687 YGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSW----VS 742
YG +TS + P + VT +T S +SW
Sbjct: 14934 YG-------------VGPGITSACIVANYPFKVPGPPGTPQVTAVTKDSMTISWHEPLSD 14980
Query: 743 ASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNI---PDLLPGRKYIVNVYQISEDGEQ 799
+ G+ VE +E + + + NI L G Y V + G+
Sbjct: 14981 GGSPILGYHVE---RKERNGILWQTVSKALVPGNIFKSSGLTDGIAYEFRVIAENMAGKS 15037
Query: 800 SLILSTSQTTAPDA---PPDPTVDQVDDTSIVVRWSRPQAP----ITGYRIVYSPSVEGS 852
+ A D P P + ++ ++W++P+ IT Y + G
Sbjct: 15038 KPSKPSEPMLALDPIDPPGKPVPLNITRHTVTLKWAKPEYTGGFKITSYIVEKRDLPNGR 15097
Query: 853 STELNLPETA-NSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPR 911
+ N N T+S L Y + A +P + + D V +P+
Sbjct: 15098 WLKANFSNILENEFTVSGLTEDAAYEFRVIAKNAAGAISPP--SEPSDAITCRDDVEAPK 15155
Query: 912 ---DLQFVEVTDVKV----------------TIMWTPPESAVTG-----YRVDVIPVNLP 947
D++F + +K T+ W+ + G ++ NL
Sbjct: 15156 IKVDVKFKDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLV 15215
Query: 948 GEHGQRLPISRNTFAEVTGLSPG--VTYYFKVFAVSH-GRESKPLTAQQTTKLDAPTNLQ 1004
+ R T +T +PG + F V + G PL + T
Sbjct: 15216 NKDSTRRDSGAYT---LTATNPGGFAKHIFNVKVLDRPGPPEGPLAVTEVTS-------- 15264
Query: 1005 FVNETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPAS 1060
++ W PP A+I Y + T R V+K + L +
Sbjct: 15265 ------EKCVLSWFPPLDDGGAKIDHYIVQKRETSRLAWTNVASEVQVTKLKVTKLLKGN 15318
Query: 1061 EYTVSLVAIK--GNQESPKATGVFTTLQPGSSIPPYNTEVTETT---IVITWTPAPRIGF 1115
EY ++A+ G E ++ V G PP N EVT T +V+ W G
Sbjct: 15319 EYIFRVMAVNKYGVGEPLESEPVLAVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGG 15378
Query: 1116 K-----LGVRPSQGGEAPREVTSDSGSIV-----VSGLTPGVEYVYTIQVLR----DGQE 1161
+ R + G+ R + + ++ VSGLT G EY + I
Sbjct: 15379 SEIINYIVERRDKAGQ--RWIKCNKKTLTDLRYKVSGLTEGHEYEFRIMAENAAGISAPS 15436
Query: 1162 RDAPIVNKVVTPLSP-PTNLHLEANPDTGVLTVSWERSTTP---DITGYRITTTPTNGQQ 1217
+P T P P + ++++W + +ITGY + +
Sbjct: 15437 PTSPFYKACDTVFKPGPPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIALPEEDE 15496
Query: 1218 GNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPEVPQLTDLSFVD 1277
+ +S T L+ EY + +Y + + P ++P P+ D
Sbjct: 15497 WQIVTPPAGLKATSYTITGLTENQEYKIRIYAMNSEGLGEP---ALVPGTPKAEDRMLPP 15553
Query: 1278 ITDSSIGLRWTPLNSSTIIGYRITVVAAGEGIP-----------IFEDFVDSSVGY-YTV 1325
+ LR + R+ V G P + + ++S+ Y +
Sbjct: 15554 EIELDADLRKV-VTIRACCTLRLFVPIKGRPAPEVKWARDHGESLDKASIESTSSYTLLI 15612
Query: 1326 TGLEPGIDYDISVITLIN--GGESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAPPPS 1383
G D ++T+ N G +SA + PP DL+ + ++ +TW PP
Sbjct: 15613 VGNVNRFDSGKYILTVENSSGSKSAFVNVRVLDTPGPPQDLKVKEVTKTSVTLTW-DPPL 15671
Query: 1384 IDLTNFLVRYSPVKNEEDVAELSISPSD---NAVVLTNLLPGTEYVVSVSSVYEQHESTP 1440
+D + + Y K E S ++ + + L G Y V + E P
Sbjct: 15672 LDGGSKIKNYIVEKRESTRKAYSTVATNCHKTSWKVDQLQEGCSYYFRVLAENEYGIGLP 15731
Query: 1441 LRGRQKTGLDS----PTGIDFSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRP 1492
+ P I D+T NS ++ W P + I GY + +
Sbjct: 15732 AETAESVKASERPLPPGKITLMDVTRNSVSLSWEKPEHDGGSRILGYIVEMQTKGSDKWA 15791
Query: 1493 REDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAA-- 1550
V + T+T L G EY + A N E + +Q +V + +DL + A
Sbjct: 15792 TCATVKVTE--ATITGLIQGEEYSFRVSAQN---EKGISDPRQLSVPVIAKDLVIPPAFK 15846
Query: 1551 ----TPTSLL---ISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGL--KP 1601
T T L + D P + +T+ + N P+++ T ++ST S L K
Sbjct: 15847 LLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKD--NVPLKQTTRVNAESTENNSLLTIKD 15904
Query: 1602 GVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQ----MQVTDVQDNSISVKWLP-- 1655
+ Y V + + + +++ +DKP +++ +V +SI++ W P
Sbjct: 15905 ACREDVGHYVVKLTNSAGEAIETLNV---IVLDKPGPPTGPVKMDEVTADSITLSWGPPK 15961
Query: 1656 --SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEG--LQPTVEYVVSVYAQNPSGE 1711
S + Y V K T + TI+ L+ EY + A+N G+
Sbjct: 15962 YDGGSSINNYIVE---KRDTSTTTWQIVSATVARTTIKACRLKTGCEYQFRIAAENRYGK 16018
Query: 1712 S-----QPLVQTAVTNIDRPKGLAFTDVDV-DSIKIAWESPQGQVSRYRVTYSSPEDGIH 1765
S +P V + P G + DS+++ W P + Y +
Sbjct: 16019 STYLNSEPTVAQYPFKVPGPPGTPVVTLSSRDSMEVQWNEPISDGGSRVIGYHLERKERN 16078
Query: 1766 ELF-------PAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTD 1818
+ P P + T GL G EY V A + +P ++ P D
Sbjct: 16079 SILWVKLNKTPIPQTKFKTT---GLEEGVEYEFRVSAENIVGIGKPSKVSECYVARDPCD 16135
Query: 1819 L----KFTQVTPTSLSAQWTPPNV----QLTGYRVRVTPKEKTGPMKEINLAPDSSSVVV 1870
+ VT S++ QW P ++TGY V + MK + V
Sbjct: 16136 PPGRPEAIIVTRNSVTLQWKKPTYDGGSKITGYIVEKKELPEGRWMKASFTNIIDTHFEV 16195
Query: 1871 SGLMVATKYEVSVYALKDT-LTSRPAQ--GVVTTLENVSPPRRARVTDATETTITISWRT 1927
+GL+ +YE V A + S P++ G +T + V PPR + +T + + +
Sbjct: 16196 TGLVEDHRYEFRVIARNAAGVFSEPSESTGAITARDEVDPPRISMDPKYKDTIVVHAGES 16255
Query: 1928 KTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQ-PGTDYKIYLYTLNDNAR--SS 1984
F+VDA P + IK D L+ TD+ L ++ D R S
Sbjct: 16256 -------FKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSL-SVKDAVRVDSG 16307
Query: 1985 PVVIDASTAIDAPS---NLRFL-------------ATTPNSLLVSWQPPR----ARITGY 2024
++ A S N++ L T ++W+PP + I Y
Sbjct: 16308 NYILKAKNVAGERSVTVNVKVLDRPGPPEGPVVISGVTAEKCTLAWKPPLQDGGSDIINY 16367
Query: 2025 IIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPL 2076
I++ + VV +T L G EYT ++A+ EPL
Sbjct: 16368 IVERRETSRLVWTVVDA-NVQTLSCKVTKLLEGNEYTFRIMAVNKYGVGEPL 16418
Score = 86.3 bits (212), Expect = 3e-16
Identities = 362/1829 (19%), Positives = 635/1829 (34%), Gaps = 273/1829 (14%)
Query: 628 IQWNAPQPS---HISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISI 684
+ WN P + I+ YI++ R + W + + + LK G Y+ ++ +
Sbjct: 17037 LSWNPPLYTGGCQITNYIVQKRDTTTTV-WDVVSATVARTTLKVTKLKTGTEYQFRIFAE 17095
Query: 685 QQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSAS 744
+YG D P+ + E P AT+ I+ S V+ W
Sbjct: 17096 NRYGQSFALESD--------PIVAQYPYKEPGPPGTPFATA-----ISKDSMVIQWHEPV 17142
Query: 745 DTVSGFRVEYELS-EEGDEPQYLDLPSTA---TSVNIPDLLPG-----RKYIVNVYQISE 795
+ + Y L +E + + + T T +L G R Y N+ + +
Sbjct: 17143 NNGGSPVIGYHLERKERNSILWTKVNKTIIHDTQFKAQNLEEGIEYEFRVYAENIVGVGK 17202
Query: 796 DGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ----APITGYRIVYSPSVEG 851
+ S P P+P + V I ++W++P + ITGY + +G
Sbjct: 17203 ASKNSECYVARDPCDPPGTPEPIM--VKRNEITLQWTKPVYDGGSMITGYIVEKRDLPDG 17260
Query: 852 ---SSTELNLPETANSVTLSDLQPGVQYNITIYA------VEENQESTPVVIQQETTGTP 902
++ N+ ET T+S L +Y + A + + +ST + ++ P
Sbjct: 17261 RWMKASFTNVIET--QFTVSGLTEDQRYEFRVIAKNAAGAISKPSDSTGPITAKDEVELP 17318
Query: 903 RSDTVPSPRDLQFVEVTDV-----------KVTIMWTPPESAVTGYRVDVIPVNLPGEHG 951
R P RD V + TI W + + E
Sbjct: 17319 RISMDPKFRDTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEI--------------EES 17364
Query: 952 QRLPISRNTFAEVTGLSPGVT-----YYFKVFAVSHGRESKPLTAQQTTKLDAPTN-LQF 1005
R I F + + + Y + V+ G +S P+ + + P +Q
Sbjct: 17365 ARCEIKNTDFKALLIVKDAIRIDGGQYILRASNVA-GSKSFPVNVKVLDRPGPPEGPVQV 17423
Query: 1006 VNETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASE 1061
T + W+PP + I+ Y + T R + + L +E
Sbjct: 17424 TGVTSEKCSLTWSPPLQDGGSDISHYVVEKRETSRLAWTVVASEVVTNSLKVTKLLEGNE 17483
Query: 1062 YTVSLVAIK--GNQESPKATGVFTT---LQPGSSIPPYNTEVT---ETTIVITWTPAPR- 1112
Y ++A+ G E ++ V + PG PP + EVT + ++ + W
Sbjct: 17484 YVFRIMAVNKYGVGEPLESAPVLMKNPFVLPG---PPKSLEVTNIAKDSMTVCWNRPDSD 17540
Query: 1113 -----IGFKLGVRPSQGGE----APREVTSDSGSIVVSGLTPGVEYVYTIQVLRD---GQ 1160
IG+ + R G R +T + V+GLT EY + + G+
Sbjct: 17541 GGSEIIGYIVEKRDRSGIRWIKCNKRRITDLR--LRVTGLTEDHEYEFRVSAENAAGVGE 17598
Query: 1161 ERDAPIVNKVVTPL---SPPTNLHLEANPDTGVLTVSWERSTTP---DITGYRITTTPTN 1214
A + K P+ PPTN H+ + +T++W + +I GY + +
Sbjct: 17599 PSPATVYYKACDPVFKPGPPTNAHI-VDTTKNSITLAWGKPIYDGGSEILGYVVEICKAD 17657
Query: 1215 GQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDK--ESVPISDTIIPE----VP 1268
++ + + L+ EY + V + E+ + T+ PE P
Sbjct: 17658 EEEWQIVTPQTGLRVTRFEISKLTEHQEYKIRVCALNKVGLGEATSVPGTVKPEDKLEAP 17717
Query: 1269 QLTDLSFVDITDSSIGLRWTPLNSSTII--GYRITVVAAGEGIPIFEDFVDSSVGYYT-V 1325
+L DL + L ++ G + +G P E G +T
Sbjct: 17718 EL-DLD-------------SELRKGIVVRAGGSARIHIPFKGRPTPEITWSREEGEFTDK 17763
Query: 1326 TGLEPGIDYD---------------ISVITLINGGESAPTTLTQQTAVPPPTDLRFTNIG 1370
+E G++Y I + +G +SA T+ PP +L +
Sbjct: 17764 VQIEKGVNYTQLSIDNCDRNDAGKYILKLENSSGSKSAFVTVKVLDTPGPPQNLAVKEVR 17823
Query: 1371 PDTMRVTWAPPPSIDLTNFLVRYSPVKNEED---VAELSISPSDNAVVLTNLLPGTEYVV 1427
D+ + W PP ID + Y K E A +S S + + NL G Y
Sbjct: 17824 KDSAFLVWEPP-IIDGGAKVKNYVIDKRESTRKAYANVSSKCSKTSFKVENLTEGAIYYF 17882
Query: 1428 SVSSVYEQHESTPLR---GRQKTGLDSPTG-IDFSDITANSFTVHWIAPR----ATITGY 1479
V + E P+ + SP G + +D++ S ++ W P + + GY
Sbjct: 17883 RVMAENEFGVGVPVETVDAVKAAEPPSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLGY 17942
Query: 1480 RIRHHPEHFSGRPREDRVPHSRN-SITLTNLTPGTEYVVSIVALNGREES-PLLIGQQST 1537
+ P+ G + V S+ + +T L+ G EY + A N + +S P ++G
Sbjct: 17943 VVEMQPK---GTEKWSIVAESKVCNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVI 17999
Query: 1538 VSDVPRDLEVVAATPTSLL-----ISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKS 1592
D+ + T + + + P + I++ + G P+++ T +
Sbjct: 18000 AKDLTIQPSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDG--EPLKQTTRVNVEE 18057
Query: 1593 TAT--ISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKP-SQMQVTDVQDNSI 1649
TAT + +K G Y VT + +++ +S+ + P ++ +V + +
Sbjct: 18058 TATSTVLHIKEGNKDDFGKYTVTATNSAGTATENLSVIVLEKPGPPVGPVRFDEVSADFV 18117
Query: 1650 SVKWLPSS----SPVTGYRV-----TTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYV 1700
+ W P + ++ Y V TTT + T +T + I L+ EY
Sbjct: 18118 VISWEPPAYTGGCQISNYIVEKRDTTTTTWHMVSATVARTT------IKITKLKTGTEYQ 18171
Query: 1701 VSVYAQNPSGESQPLVQTAVT-----NIDRPKGLAF-TDVDVDSIKIAWESPQGQVSRYR 1754
++A+N G+S PL AV P G F T + D + + W P
Sbjct: 18172 FRIFAENRYGKSAPLDSKAVIVQYPFKEPGPPGTPFVTSISKDQMLVQWHEPVNDGGTKI 18231
Query: 1755 VTYSSPEDGIHELF-------PAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIG 1807
+ Y + + + P D + T GL G EY V A + +P
Sbjct: 18232 IGYHLEQKEKNSILWVKLNKTPIQDTKFKTT---GLDEGLEYEFKVSAENIVGIGKPSKV 18288
Query: 1808 TQSTAIPAPTD----LKFTQVTPTSLSAQWTPP----NVQLTGYRVRVTPKEKTGPMKEI 1859
++ P D + +T +++ +W P ++TGY V MK
Sbjct: 18289 SECFVARDPCDPPGRPEAIVITRNNVTLKWKKPAYDGGSKITGYIVEKKDLPDGRWMKAS 18348
Query: 1860 NLAPDSSSVVVSGLMVATKYEVSVYALKDTLT-SRP--AQGVVTTLENVSPPRRAR---- 1912
+ VSGL+ +YE V A S P + G +T + + P +
Sbjct: 18349 FTNVLETEFTVSGLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARDEIDAPNASLDPKY 18408
Query: 1913 ----VTDATET-TITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQ-P 1966
V A ET + R K + D +T + IK ++ T+
Sbjct: 18409 KDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELE-ETAARMEIKSTIQKTTLVVKDCI 18467
Query: 1967 GTDYKIYLYTLND--NARSSPVVIDASTAIDAPSN-LRFLATTPNSLLVSWQPP----RA 2019
TD Y+ L++ +S P+ + P L+ T ++W PP A
Sbjct: 18468 RTDGGQYILKLSNVGGTKSIPITVKVLDRPGPPEGPLKVTGVTAEKCYLAWNPPLQDGGA 18527
Query: 2020 RITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGR 2079
I+ YII+ + V + +T L PG EY V+A+ EPL
Sbjct: 18528 NISHYIIEKRETSRLSWTQVSTEVQAL-NYKVTKLLPGNEYIFRVMAVNKYGIGEPL--- 18583
Query: 2080 KKTDELPQLVTLPHPNLHGPEILDVPSTVQKTPFVTHPGYDTGNGIQLPGTSGQQPSVGQ 2139
+ P P+ P +V + + + VT G ++ G ++
Sbjct: 18584 ---ESGPVTACNPYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILEKR---- 18636
Query: 2140 QMIFEEHGFRRT-TPPTTATPIRHR------PRPYPPNVGEE--IQIGHIPREDVDYH-- 2188
++ G R T T T +R R Y V E +G V Y
Sbjct: 18637 ----DKEGVRWTKCNKKTLTDLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRAC 18692
Query: 2189 --LYPHGPGLNPNASTGQEALSQTTISWA-PFQD----TSEYIISCHPVGTDEEPLQFRV 2241
LYP GP NP + + S +++W+ P D Y++ DE
Sbjct: 18693 DALYPPGPPSNPKVT--DTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAADEWTTCTPP 18750
Query: 2242 PG-TSTSATLTGLTRGATYNIIVEALKDQ 2269
G T+T L YN + A+ +
Sbjct: 18751 TGLQGKQFTVTKLKENTEYNFRICAINSE 18779
Score = 84.3 bits (207), Expect = 1e-15
Identities = 263/1195 (22%), Positives = 417/1195 (34%), Gaps = 139/1195 (11%)
Query: 624 NSHPIQWNAPQ---PSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQ 680
N+ + WN P+ S I Y+L R + K YT+KGLK G YE +
Sbjct: 10426 NTVTLTWNPPKYDGGSEIINYVLESRLIGTEKFHKVTNDNLLSRKYTVKGLKEGDTYEYR 10485
Query: 681 LISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSW 740
+ ++ G + + + P+T E P + + + +T +F ++
Sbjct: 10486 VSAVNIVGQGK-------PSFCTKPITCK---DELAPPTLHLDFRDKLTIRVGEAFALTG 10535
Query: 741 ---VSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNI-PDLLPGRKYIVNVYQISED 796
VS F+ E ++ E+ D P+T I KY V V +
Sbjct: 10536 RYSGKPKPKVSWFKDEADVLED-DRTHIKTTPATLALEKIKAKRSDSGKYCVVVE--NST 10592
Query: 797 GEQSLILSTSQTTAPDAPPDP-TVDQVDDTSIVVRWSRP----QAPITGYRIVYSPSVEG 851
G + + P P P + D+V +V+ W P + IT Y I +
Sbjct: 10593 GSRKGFCQVNVVDRPGPPVGPVSFDEVTKDYMVISWKPPLDDGGSKITNYIIEKKEVGKD 10652
Query: 852 SSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPR 911
+ + +S L G Y I+A S P+V ++ VP
Sbjct: 10653 VWMPVTSASAKTTCKVSKLLEGKDYIFRIHAENLYGISDPLV--SDSMKAKDRFRVPDAP 10710
Query: 912 DLQFV-EVTDVKVTIMWTPPESA---VTGYRVDV-IPVNLPGEHGQRLPISRNTFAEVTG 966
D V EVT + W P +T Y ++ ++ + PI T V
Sbjct: 10711 DQPIVTEVTKDSALVTWNKPHDGGKPITNYILEKRETMSKRWARVTKDPIHPYTKFRVPD 10770
Query: 967 LSPGVTYYFKVFAVSH------GRESKPLTAQQ-TTKLDAPTNLQFVNETDSTVLVRWTP 1019
L G Y F+V A + SKP+ A+ K P N + ++ T ++V + W P
Sbjct: 10771 LLEGCQYEFRVSAENEIGIGDPSPPSKPVFAKDPIAKPSPPVNPEAIDTTCNSVDLTWQP 10830
Query: 1020 PR----AQITGYRLTVGLTRRGQPRQYNVGPS---VSKYPLRNLQPASEYTVSLVAIKGN 1072
PR ++I GY + + R+ N P +KY + L+ Y ++A+
Sbjct: 10831 PRHDGGSKILGYIVEYQKVGDEEWRRANHTPESCPETKYKVTGLRDGQTYKFRVLAVNAA 10890
Query: 1073 QES-----PKATGVFTTLQPGSSIPPYNT---------EVTETTIVITWTPAPRIGFKLG 1118
ES P+ V L+P I N + + +I P P++ +K
Sbjct: 10891 GESDPAHVPEPVLVKDRLEPPELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKE 10950
Query: 1119 VRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPT 1178
R + +A +VT + + +Y++ V + + V+ PP
Sbjct: 10951 DRDAP-TKARIDVTPVGSKLEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDKPGPPR 11009
Query: 1179 NLHL-EANPDTGVLTVSWERSTTPD---ITGYRITTTPTNGQQGNSLEEVVHADQSSCTF 1234
+L + E D+ LT W+ IT Y + Q + L + + S
Sbjct: 11010 DLEVSEIRKDSCYLT--WKEPLDDGGSVITNYVVERRDVASAQWSPLSAT--SKKKSHFA 11065
Query: 1235 DNLSPGLEYNVSVYTVK--------DDKESVPISDTIIPEVPQLTDLSFVDITDSSIGLR 1286
+L+ G +Y V + + + D + P P DL VD+ + + L
Sbjct: 11066 KHLNEGNQYLFRVAAENQYGRGPFVETPKPIKALDPLHPPGPP-KDLHHVDVDKTEVSLV 11124
Query: 1287 WTPLN---SSTIIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLIN 1343
W + S I GY V EG + F + VTGL+ G Y V
Sbjct: 11125 WNKPDRDGGSPITGY--LVEYQEEGTQDWIKFKTVTNLECVVTGLQQGKTYRFRVKAENI 11182
Query: 1344 GGESAPTTL----TQQTAVPPPTDLRFTNI------GPDTMR----VTWAPPPSIDLTNF 1389
G P T Q+ VPP +L I T+R + P P+ T
Sbjct: 11183 VGLGLPDTTIPIECQEKLVPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWT-- 11240
Query: 1390 LVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGT-EYVVSVSSVYEQHESTPLRGRQKTG 1448
S +K +E + + S + L T EY ++VS+ + T
Sbjct: 11241 -TDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEYQITVSNA----AGSKTVAVHLTV 11295
Query: 1449 LD---SPTG-IDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSI 1504
LD PTG I+ D+T T+ W P+ I + E R V S +S
Sbjct: 11296 LDVPGPPTGPINILDVTPEHMTISWQPPKDDGGSPVINYIVEKQDTRKDTWGVVSSGSSK 11355
Query: 1505 T---LTNLTPGTEYVVSIVALN------GREESPLLIGQQSTVSDVPRDLEVVAATPTSL 1555
T + +L G EYV + A N + +P + + + P V T +
Sbjct: 11356 TKLKIPHLQKGCEYVFRVRAENKIGVGPPLDSTPTVAKHKFSPPSPPGKPVVTDITENAA 11415
Query: 1556 LISWDAP-----AVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVY 1610
+SW P + YY TG V + + K T GL G Y V+
Sbjct: 11416 TVSWTLPKSDGGSPITGYYMERREVTGKWVRVNKTPIADLKFRVT--GLYEGNTYEFRVF 11473
Query: 1611 AVTGRGDSPASSKPISINYRTEIDKPS---QMQVTDVQDNSISVKWL----PSSSPVTGY 1663
A G S S I I P ++ D + + W SP+ GY
Sbjct: 11474 AENLAGLSKPSPSSDPIKACRPIKPPGPPINPKLKDKSRETADLVWTKPLSDGGSPILGY 11533
Query: 1664 RVTTTPKNGPGPTKTKTAGPD----QTEMTIEGLQPTVEYVVSVYAQNPSGESQP 1714
V PG + D Q + GL EY + A N GE +P
Sbjct: 11534 VVEC---QKPGTAQWNRINKDELIRQCAFRVPGLIEGNEYRFRIKAANIVGEGEP 11585
Score = 83.2 bits (204), Expect = 3e-15
Identities = 182/840 (21%), Positives = 295/840 (35%), Gaps = 117/840 (13%)
Query: 1338 VITLIN--GGESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAPPPS---IDLTNFLVR 1392
V+T N G A T+ P +L+ ++ D V W PP ++ N+++
Sbjct: 11970 VVTATNTAGSFVAYATVNVLDKPGPVRNLKIVDVSSDRCTVCWDPPEDDGGCEIQNYILE 12029
Query: 1393 YSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQ---KTGL 1449
K + S + +T L+ G EY+ V + + P + KT
Sbjct: 12030 KCETKRMV-WSTYSATVLTPGTTVTRLIEGNEYIFRVRAENKIGTGPPTESKPVIAKTKY 12088
Query: 1450 DSPTGIDFSDITANS---FTVHWIAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRN 1502
D P D ++T S TV W P +ITGY + +H + ++
Sbjct: 12089 DKPGRPDPPEVTKVSKEEMTVVWNPPEYDGGKSITGYFLEKKEKHSTRWVPVNKSAIPER 12148
Query: 1503 SITLTNLTPGTEYVVSIVALN-------GREESPLLIGQQSTVSDVPRDLEVVAATPTSL 1555
+ + NL P EY + A N P++ P + VV T S+
Sbjct: 12149 RMKVQNLLPDHEYQFRVKAENEIGIGEPSLPSRPVVAKDPIEPPGPPTNFRVVDTTKHSI 12208
Query: 1556 LISWDAP-----AVTVRYYRITYGETGGNSPVQEFTVPGS-----KSTATISGLKPGVDY 1605
+ W P A + Y + SP + + + + T++ L +Y
Sbjct: 12209 TLGWGKPVYDGGAPIIGYVVEMRPKIADASPDEGWKRCNAAAQLVRKEFTVTSLDENQEY 12268
Query: 1606 TITVYAVTGRG-DSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYR 1664
V A G PA K E KP ++ D S++ L R
Sbjct: 12269 EFRVCAQNQVGIGRPAELK--------EAIKPKEILEPPEIDLDASMRKLVIVRAGCPIR 12320
Query: 1665 VTTTPKNGPGPTKT-KTAGPDQTEMTIE-GLQPTVEYVV------------SVYAQNPSG 1710
+ + P P T + G D + L T+ ++V S+ NP+G
Sbjct: 12321 LFAIVRGRPAPKVTWRKVGIDNVVRKGQVDLVDTMAFLVIPNSTRDDSGKYSLTLVNPAG 12380
Query: 1711 ESQPLVQTAVTNIDRP-KGLAFTDVDVDSIKIAWESPQG----QVSRYRVTYSSPEDGIH 1765
E V V + P L +DV S ++W P+ QV+ Y V +
Sbjct: 12381 EKAVFVNVRVLDTPGPVSDLKVSDVTKTSCHVSWAPPENDGGSQVTHYIVEKREADRKTW 12440
Query: 1766 ELFPAPDGEEDTAELQGLRPGSEYTVSVVALHD-------DMESQPLIGTQSTAIPAPTD 1818
P+ ++ + + L PG+EY V A+++ D+ L + P
Sbjct: 12441 STV-TPEVKKTSFHVTNLVPGNEYYFRVTAVNEYGPGVPTDVPKPVLASDPLSEPDPPRK 12499
Query: 1819 LKFTQVTPTSLSAQWTPP--------NVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVV 1870
L+ T++T S + W PP + +T YR P ++ E ++ D S +VV
Sbjct: 12500 LEVTEMTKNSATLAWLPPLRDGGAKIDGYITSYREEEQPADR---WTEYSVVKDLS-LVV 12555
Query: 1871 SGLMVATKYEVSVYALKDTLTSRP--AQGVVTTLENVSPPRRARVTDAT----------- 1917
+GL KY+ V A S P A+GV E + PP+ T
Sbjct: 12556 TGLKEGKKYKFRVAARNAVGVSLPREAEGVYEAKEQLLPPKILMPEQITIKAGKKLRIEA 12615
Query: 1918 ----ETTITISWRT-KTETITGFQVDAVPANGQTP--IQRTIKPDVRSYTITGLQPGTDY 1970
+ T W+ + E +T + A+ + I+ + D Y++T
Sbjct: 12616 HVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGYYSLTAENSSG-- 12673
Query: 1971 KIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYII 2026
D + VV+DA P ++ + SL SW P + IT YI+
Sbjct: 12674 -------TDTQKIKVVVMDAPGPPQPPFDISDIDADACSL--SWHIPLEDGGSNITNYIV 12724
Query: 2027 KYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELP 2086
+ + S V T + L PG EY V A SEPL K + P
Sbjct: 12725 E-KCDVSRGDWVTALASVTKTSCRVGKLIPGQEYIFRVRAENRFGISEPLTSPKMVAQFP 12783
Score = 80.1 bits (196), Expect = 2e-14
Identities = 310/1425 (21%), Positives = 524/1425 (36%), Gaps = 261/1425 (18%)
Query: 780 LLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPIT 839
++P ++Y++ V ++ G + A D PT+D IV+ + P+
Sbjct: 8045 VVPDKEYVLRVRAVNAIGVSEPSEISENVVAKDPDCKPTIDLETHDIIVIEGEKLSIPVP 8104
Query: 840 GYRIVYSPSV----EGSSTELNLPETANSVTLS---DLQPGVQYNITIYAV--EENQEST 890
+R V P+V +G + + T + +S ++ V+ + IY + E S
Sbjct: 8105 -FRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSA 8163
Query: 891 PVVIQQETTGTPRSDTVPSP-RDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGE 949
I + G +P P +D++ ++T + W PPE G + V E
Sbjct: 8164 TASINVKVIG------LPGPCKDIKASDITKSSCKLTWEPPE--FDGGTPILHYVLERRE 8215
Query: 950 HGQR--LPI--SRNTFA-EVTGLSPGVTYYFKVFAVSH--GRE----SKPLTAQQTTKL- 997
G+R +P+ N + V L P Y+F+V AV+ G E P+ AQ +
Sbjct: 8216 AGRRTYIPVMSGENKLSWTVKDLIPNGEYFFRVKAVNKVGGGEYIELKNPVIAQDPKQPP 8275
Query: 998 DAPTNLQFVNETDSTVLVRWTPPR----AQITGY---RLTVGLTRRGQPRQYNVGPSVSK 1050
D P +++ N T + + W PP ++I GY ++ G R + ++ V +
Sbjct: 8276 DPPVDVEVHNPTAEAMTITWKPPLYDGGSKIMGYIIEKIAKGEERWKRCNEHLV--PILT 8333
Query: 1051 YPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPA 1110
Y + L+ EY + A A G+ +P + PP T + A
Sbjct: 8334 YTAKGLEEGKEYQFRVRA-------ENAAGIS---EPSRATPP--------TKAVDPIDA 8375
Query: 1111 PRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVL--RDGQERDAPIVN 1168
P++ + + +G E + S SGS P + ++ V+ + ++R AP+V
Sbjct: 8376 PKVILRTSLEVKRGDEIALDA-SISGSPY-----PTITWIKDENVIVPEEIKKRAAPLVR 8429
Query: 1169 KVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHAD 1228
+ + L P T L++ N ++G S V
Sbjct: 8430 RRKGEVQEEEPFVL---PLTQRLSID-------------------NSKKGESQLRVR--- 8464
Query: 1229 QSSCTFDNLSPGLEYNVSVYTVKDDK--ESVPISDTIIPEVPQLTDLSFVDITDSSIGLR 1286
D+L P ++ + + V++D P + +++ + F DI +S+ +
Sbjct: 8465 ------DSLRP--DHGLYMIKVENDHGIAKAPCTVSVLDTPGPPINFVFEDIRKTSVLCK 8516
Query: 1287 WTPL---NSSTIIGYRITVVAAGEGIPIFEDFVDSSV---GYYTVTGLEPGIDYDISVIT 1340
W P S II Y T+ + P E V +S Y+VT L G +Y V
Sbjct: 8517 WEPPLDDGGSEIINY--TLEKKDKTKPDSEWIVVTSTLRHCKYSVTKLIEGKEYLFRVRA 8574
Query: 1341 LINGGESAPTTLTQQTAVPP------PTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYS 1394
G P A P P ++ ++M V W P D + ++ Y
Sbjct: 8575 ENRFGPGPPCVSKPLVAKDPFGPPDAPDKPIVEDVTSNSMLVKWNEPK--DNGSPILGYW 8632
Query: 1395 PVKNEEDVAELS-ISPSDNAVVLTN---LLPGTEYVVSVSSVYEQHESTPLR----GRQK 1446
K E + S ++ S + N LL G YV V + ++ + P + K
Sbjct: 8633 LEKREVNSTHWSRVNKSLLNALKANVDGLLEGLTYVFRVCA---ENAAGPGKFSPPSDPK 8689
Query: 1447 TGLD--SPTGIDFSDITANSFT---VHWIAPR----ATITGYRIRHHPEHFSGRPREDRV 1497
T D SP G +T S T + W P I GY + + R
Sbjct: 8690 TAHDPISPPGPPIPRVTDTSSTTIELEWEPPAFNGGGEIVGYFVDKQLVGTNEWSRCTEK 8749
Query: 1498 PHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLI 1557
T+ + G +Y + + A+N E P Q TV++ P++ A + +
Sbjct: 8750 MIKVRQYTVKEIREGADYKLRVSAVNAAGEGPPGETQPVTVAE-PQE---PPAVELDVSV 8805
Query: 1558 SWDAPAVTVRYYRITYGETGGNSPVQEFTVP--------------GSKSTATISGL--KP 1601
+ + RI TG P + +T G+KS I K
Sbjct: 8806 KGGIQIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKDRVVIDNVGTKSELIIKDALRKD 8865
Query: 1602 GVDYTITVYAVTGRGDSPA------------SSKPISINYRTEIDKPSQMQVTDVQDNSI 1649
Y IT G + A KP+ N K + +D +D+
Sbjct: 8866 HGRYVITATNSCGSKFAAARVEVFDVPGPVLDLKPVVTNR-----KMCLLNWSDPEDDG- 8919
Query: 1650 SVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPS 1709
S +TG+ + K+ T + ++++ I GL EY V A+N
Sbjct: 8920 -------GSEITGFIIER--KDAKMHTWRQPIETERSKCDITGLLEGQEYKFRVIAKNKF 8970
Query: 1710 GESQPLVQTAVTNID------RPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDG 1763
G P+ + +D P+ L +T+ +I + W+ P R SP G
Sbjct: 8971 GCGPPVEIGPILAVDPLGPPTSPERLTYTERTKSTITLDWKEP-------RSNGGSPIQG 9023
Query: 1764 I---HELFPAPDGEEDTAEL--------QGLRPGSEYTVSVVALHDDMESQPLIGTQSTA 1812
PD E L + L Y V A+++ ES+P +
Sbjct: 9024 YIIEKRRHDKPDFERVNKRLCPTTSFLVENLDEHQMYEFRVKAVNEIGESEP-------S 9076
Query: 1813 IPAPTDLKFTQVTPT---SLSAQWTPPNVQLTGYRVRVTPKEKTG-PMKEINLAPDSSSV 1868
+P ++ +V PT LS + V+ G V + P + TG PM +I + + + +
Sbjct: 9077 LPLNVVIQDDEVPPTIKLRLSVRGDTIKVK-AGEPVHI-PADVTGLPMPKIEWSKNETVI 9134
Query: 1869 VV-SGLMVATKYEVS-------------VYALKDTLTSRPAQGVVTTLENV--------S 1906
+ + TK EVS V K T T + + + NV S
Sbjct: 9135 EKPTDALQITKEEVSRSEAKTELSIPKAVREDKGTYTVTASNRLGSVFRNVHVEVYDRPS 9194
Query: 1907 PPRRARVTDATETTITISWRTKTET----ITGFQVDAVPANGQTPIQRTIKPDV--RSYT 1960
PPR VTD + ++W + IT + +D A+ + + + Y
Sbjct: 9195 PPRNLAVTDIKAESCYLTWDAPLDNGGSEITHYVIDKRDASRKKAEWEEVTNTAVEKRYG 9254
Query: 1961 ITGLQPGTDYKIYL-----YTLNDNARSSPVVI-DASTAIDAPSNLRFLATTPNSLLVSW 2014
I L P Y+ + Y ++D +S VVI D P + LA T S+LVSW
Sbjct: 9255 IWKLIPNGQYEFRVRAVNKYGISDECKSDKVVIQDPYRLPGPPGKPKVLARTKGSMLVSW 9314
Query: 2015 QPP----RARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLE 2055
PP + ITGY ++ + GSP V R +T+ + G+E
Sbjct: 9315 TPPLDNGGSPITGYWLEKREEGSPYWSRV--SRAPITKVGLKGVE 9357
Score = 78.2 bits (191), Expect = 9e-14
Identities = 286/1430 (20%), Positives = 494/1430 (34%), Gaps = 241/1430 (16%)
Query: 690 QEVTRFDFTTTSTST---------------PVTSNTVTGET-------------TPFSPL 721
++ R +F TT+TST P+T+ + GE P P+
Sbjct: 14802 KQTQRVNFETTATSTILNINECVRSDSGPYPLTARNIVGEVGDVITIQVHDIPGPPTGPI 14861
Query: 722 VATSESVTEITASSFVVSWVSASD----TVSGFRVEYELSEEGDEPQYLDLPSTA--TSV 775
E+++ SW + +S + VE + D +++L +T T+
Sbjct: 14862 -----KFDEVSSDFVTFSWDPPENDGGVPISNYVVE---MRQTDSTTWVELATTVIRTTY 14913
Query: 776 NIPDLLPGRKY-----IVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVR 830
L G +Y N Y + + I++ P P P V V S+ +
Sbjct: 14914 KATRLTTGLEYQFRVKAQNRYGVGPGITSACIVANYPFKVPGPPGTPQVTAVTKDSMTIS 14973
Query: 831 WSRP----QAPITGYRIVYSPSVEGSSTELNLPETANSVTL-------SDLQPGVQYNIT 879
W P +PI GY VE L +T + + S L G+ Y
Sbjct: 14974 WHEPLSDGGSPILGYH------VERKERNGILWQTVSKALVPGNIFKSSGLTDGIAYEFR 15027
Query: 880 IYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESA----VT 935
+ A +S P + D P L +T VT+ W PE +T
Sbjct: 15028 VIAENMAGKSKPSKPSEPMLALDPIDPPGKPVPL---NITRHTVTLKWAKPEYTGGFKIT 15084
Query: 936 GYRVDVIPVNLPGEHGQRLPIS---RNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQ 992
Y V+ +LP + S N F V+GL+ Y F+V A + P +
Sbjct: 15085 SYIVE--KRDLPNGRWLKANFSNILENEFT-VSGLTEDAAYEFRVIAKNAAGAISPPSEP 15141
Query: 993 QTT-----KLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQP-RQYNVGP 1046
++AP V D+ +L +RL ++ R P +++
Sbjct: 15142 SDAITCRDDVEAPKIKVDVKFKDTVILKAG-------EAFRLEADVSGRPPPTMEWSKDG 15194
Query: 1047 SVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSI-------------PP 1093
+ + ++++ +LV K + T PG PP
Sbjct: 15195 KELEGTAKLEIKIADFSTNLVN-KDSTRRDSGAYTLTATNPGGFAKHIFNVKVLDRPGPP 15253
Query: 1094 YN----TEVTETTIVITW-TPAPRIGFKLGVRPSQGGEAPREVTSDSGSIV------VSG 1142
TEVT V++W P G K+ Q E R ++ S V V+
Sbjct: 15254 EGPLAVTEVTSEKCVLSWFPPLDDGGAKIDHYIVQKRETSRLAWTNVASEVQVTKLKVTK 15313
Query: 1143 LTPGVEYVYTIQVLRD---GQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLT-----VS 1194
L G EY++ + + G+ ++ V V P PP NP+ +T V
Sbjct: 15314 LLKGNEYIFRVMAVNKYGVGEPLESEPV-LAVNPYGPPDP---PKNPEVTTITKDSMVVC 15369
Query: 1195 W---ERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVK 1251
W + +I Y + GQ+ + D L+ G EY +
Sbjct: 15370 WGHPDSDGGSEIINYIVERRDKAGQRWIKCNKKTLTD-LRYKVSGLTEGHEYEFRIMAEN 15428
Query: 1252 DDKESVP--------ISDTIIPEVPQLTDLSFVDITDSSIGLRWT-PL--NSSTIIGYRI 1300
S P DT+ P + +D + SSI + W P+ S I GY +
Sbjct: 15429 AAGISAPSPTSPFYKACDTVFKPGPP-GNPRVLDTSRSSISIAWNKPIYDGGSEITGYMV 15487
Query: 1301 TVVAAGEG-IPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAP-----TTLTQ 1354
+ E I YT+TGL +Y I + + + G P T +
Sbjct: 15488 EIALPEEDEWQIVTPPAGLKATSYTITGLTENQEYKIRIYAMNSEGLGEPALVPGTPKAE 15547
Query: 1355 QTAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNE------------EDV 1402
+PP +L D +V +I L + P+K E +
Sbjct: 15548 DRMLPPEIEL-----DADLRKVV-----TIRACCTLRLFVPIKGRPAPEVKWARDHGESL 15597
Query: 1403 AELSISPSDNAVVL----TNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFS 1458
+ SI + + +L N +Y+++V + +S + R P +
Sbjct: 15598 DKASIESTSSYTLLIVGNVNRFDSGKYILTVEN-SSGSKSAFVNVRVLDTPGPPQDLKVK 15656
Query: 1459 DITANSFTVHWIAPRATITGYRIRHH--PEHFSGRPREDRVPHS--RNSITLTNLTPGTE 1514
++T S T+ W P G +I+++ + S R V + + S + L G
Sbjct: 15657 EVTKTSVTLTWDPPLLD-GGSKIKNYIVEKRESTRKAYSTVATNCHKTSWKVDQLQEGCS 15715
Query: 1515 YVVSIVALN----GREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAP----AVTV 1566
Y ++A N G + S P + ++ T S+ +SW+ P +
Sbjct: 15716 YYFRVLAENEYGIGLPAETAESVKASERPLPPGKITLMDVTRNSVSLSWEKPEHDGGSRI 15775
Query: 1567 RYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPIS 1626
Y + G + TV + ATI+GL G +Y+ V A +G S +
Sbjct: 15776 LGYIVEMQTKGSDKWATCATV--KVTEATITGLIQGEEYSFRVSAQNEKGISDPRQLSVP 15833
Query: 1627 INYRTEIDKP------SQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKT 1680
+ + + P + V +D + V ++ +P + P +T
Sbjct: 15834 VIAKDLVIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLK-----QTTR 15888
Query: 1681 AGPDQTE----MTIEGL--QPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRP----KGLA 1730
+ TE +TI+ + YVV + N +GE+ + V +D+P +
Sbjct: 15889 VNAESTENNSLLTIKDACREDVGHYVVKL--TNSAGEAIETLNVIV--LDKPGPPTGPVK 15944
Query: 1731 FTDVDVDSIKIAWESPQ----GQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPG 1786
+V DSI ++W P+ ++ Y V ++ A T + L+ G
Sbjct: 15945 MDEVTADSITLSWGPPKYDGGSSINNYIVEKRDTSTTTWQIVSATVA-RTTIKACRLKTG 16003
Query: 1787 SEYTVSVVALH-----DDMESQPLIGTQSTAIPAPTDLK-FTQVTPTSLSAQWTPP---- 1836
EY + A + + S+P + +P P T + S+ QW P
Sbjct: 16004 CEYQFRIAAENRYGKSTYLNSEPTVAQYPFKVPGPPGTPVVTLSSRDSMEVQWNEPISDG 16063
Query: 1837 NVQLTGYRVRVTPKEKTGPM-KEINLAP-DSSSVVVSGLMVATKYEVSVYALKDTLTSRP 1894
++ GY + KE+ + ++N P + +GL +YE V A +P
Sbjct: 16064 GSRVIGYHLE--RKERNSILWVKLNKTPIPQTKFKTTGLEEGVEYEFRVSAENIVGIGKP 16121
Query: 1895 AQ--GVVTTLENVSPPRRARVTDATETTITISWRTKT----ETITGFQVD 1938
++ + PP R T ++T+ W+ T ITG+ V+
Sbjct: 16122 SKVSECYVARDPCDPPGRPEAIIVTRNSVTLQWKKPTYDGGSKITGYIVE 16171
Score = 75.1 bits (183), Expect = 8e-13
Identities = 286/1351 (21%), Positives = 472/1351 (34%), Gaps = 234/1351 (17%)
Query: 797 GEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ----APITGYRIVYSPSVEGS 852
G +++ + P P D V ++ S + W P + IT Y +
Sbjct: 10991 GSKTVSVKVLVLDKPGPPRDLEVSEIRKDSCYLTWKEPLDDGGSVITNYVVERRDVASAQ 11050
Query: 853 STELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRD 912
+ L+ S L G QY + A + V + P+D
Sbjct: 11051 WSPLSATSKKKSHFAKHLNEGNQYLFRVAAENQYGRGPFVETPKPIKALDPLHPPGPPKD 11110
Query: 913 LQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPVNLPGEHGQRLPISRNTFAE----V 964
L V+V +V+++W P+ S +TGY V+ E G + I T V
Sbjct: 11111 LHHVDVDKTEVSLVWNKPDRDGGSPITGYLVEY------QEEGTQDWIKFKTVTNLECVV 11164
Query: 965 TGLSPGVTYYFKVFA---VSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPR 1021
TGL G TY F+V A V G + + KL P+ V + V+ T R
Sbjct: 11165 TGLQQGKTYRFRVKAENIVGLGLPDTTIPIECQEKLVPPSVELDVKLIEGLVVKAGTTVR 11224
Query: 1022 --AQITGYRL-TVGLTRRGQPRQYNVGPSV------SKYPLRNL--QPASEYTVSLVAIK 1070
A I G + T T G + + +V S ++N + EY +++
Sbjct: 11225 FPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEYQITV---- 11280
Query: 1071 GNQESPKATGVFTTLQ--PGSSIPPYNT-EVTETTIVITWTPAPRIGFKLGVRPSQGGEA 1127
N K V T+ PG P N +VT + I+W P P G +
Sbjct: 11281 SNAAGSKTVAVHLTVLDVPGPPTGPINILDVTPEHMTISWQP-----------PKDDGGS 11329
Query: 1128 P--------REVTSDSGSIVVSG----------LTPGVEYVYTIQV---LRDGQERDA-P 1165
P ++ D+ +V SG L G EYV+ ++ + G D+ P
Sbjct: 11330 PVINYIVEKQDTRKDTWGVVSSGSSKTKLKIPHLQKGCEYVFRVRAENKIGVGPPLDSTP 11389
Query: 1166 IVNK-VVTPLSPPTNLHLEANPDTGVLTVSWERSTTPD---ITGY------------RIT 1209
V K +P SPP + + TVSW + ITGY R+
Sbjct: 11390 TVAKHKFSPPSPPGK-PVVTDITENAATVSWTLPKSDGGSPITGYYMERREVTGKWVRVN 11448
Query: 1210 TTP--------TNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISD 1261
TP T +GN+ E V A+ NL+ + + S +K + PI
Sbjct: 11449 KTPIADLKFRVTGLYEGNTYEFRVFAE-------NLAGLSKPSPSSDPIKACR---PIKP 11498
Query: 1262 TIIPEVPQLTDLSFVDITDSSIGLRWT-PLNS--STIIGYRITVVAAG--EGIPIFEDFV 1316
P P+L D S + L WT PL+ S I+GY + G + I +D +
Sbjct: 11499 PGPPINPKLKDKS-----RETADLVWTKPLSDGGSPILGYVVECQKPGTAQWNRINKDEL 11553
Query: 1317 DSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAV-----PPPTDLRFTNIGP 1371
+ V GL G +Y + GE P L + PP +L T
Sbjct: 11554 IRQCAF-RVPGLIEGNEYRFRIKAANIVGEGEPRELAESVIAKDILHPPEVELDVTCRDV 11612
Query: 1372 DTMRVTWA----------PPPSIDLTN---FLVRYSPVKNEEDV--AELSISPSDNAVVL 1416
T+RV P P I T LVR V +D+ EL I + A
Sbjct: 11613 ITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRA--- 11669
Query: 1417 TNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSP---TGIDFSDITANSFTVHWIAPR 1473
+Y++S + + + + LD P + +++T + T+ W P
Sbjct: 11670 ----DHGKYIISAKNSSGHAQGSAI----VNVLDRPGPCQNLKVTNVTKENCTISWENPL 11721
Query: 1474 ----ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNG----- 1524
+ IT + + + + G R + NL EY + A N
Sbjct: 11722 DNGGSEITNFIVEYRKPNQKGWSIVASDVTKR--LIKANLLANNEYYFRVCAENKVGVGP 11779
Query: 1525 --REESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYG---ETGGN 1579
++P+L P +L + T + + W P ++Y G+
Sbjct: 11780 TIETKTPILAINPIDRPGEPENLHIADKGKTFVYLKWRRPDYDGGSPNLSYHVERRLKGS 11839
Query: 1580 SPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASS--KPISINYRTEIDKPS 1637
+ K T + + V+ I + V + + S K + + ++ KP
Sbjct: 11840 DDWERVHKGSIKETHYM--VDRCVENQIYEFRVQTKNEGGESDWVKTEEVVVKEDLQKP- 11896
Query: 1638 QMQVTDVQDNSIS-VKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMT------I 1690
V D +S V + + + R+ + P P T D T++T I
Sbjct: 11897 ------VLDLKLSGVLTVKAGDTI---RLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKI 11947
Query: 1691 EGLQPTVEYVVSVYAQNPSGE--------SQPLVQTAVTNI-DRP---KGLAFTDVDVDS 1738
+ + ++ ++ ++ G+ + V A N+ D+P + L DV D
Sbjct: 11948 DTRADSSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATVNVLDKPGPVRNLKIVDVSSDR 12007
Query: 1739 IKIAWESPQG----QVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSV- 1793
+ W+ P+ ++ Y + + + + A T + L G+EY V
Sbjct: 12008 CTVCWDPPEDDGGCEIQNYILEKCETKRMVWSTYSATVLTPGTTVTR-LIEGNEYIFRVR 12066
Query: 1794 ----VALHDDMESQPLIGTQSTAIPA-PTDLKFTQVTPTSLSAQWTPPNVQ----LTGYR 1844
+ ES+P+I P P + T+V+ ++ W PP +TGY
Sbjct: 12067 AENKIGTGPPTESKPVIAKTKYDKPGRPDPPEVTKVSKEEMTVVWNPPEYDGGKSITGYF 12126
Query: 1845 VRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKD------TLTSRPAQGV 1898
+ K T + A + V L+ +Y+ V A + +L SRP
Sbjct: 12127 LEKKEKHSTRWVPVNKSAIPERRMKVQNLLPDHEYQFRVKAENEIGIGEPSLPSRPVVAK 12186
Query: 1899 VTTLENVSPPRRARVTDATETTITISWRTKT----ETITGFQV-------DAVPANGQTP 1947
+E PP RV D T+ +IT+ W I G+ V DA P G
Sbjct: 12187 -DPIEPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAPIIGYVVEMRPKIADASPDEGWKR 12245
Query: 1948 IQRTIKPDVRSYTITGLQPGTDYKIYLYTLN 1978
+ + +T+T L +Y+ + N
Sbjct: 12246 CNAAAQLVRKEFTVTSLDENQEYEFRVCAQN 12276
Score = 71.2 bits (173), Expect = 1e-11
Identities = 350/1644 (21%), Positives = 556/1644 (33%), Gaps = 296/1644 (18%)
Query: 628 IQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISI 684
+ W +P+ S I+ Y++ R + W T + T++GL G Y ++ +
Sbjct: 10330 LTWFSPEDDGGSPITNYVIEKRESDRRA-WTPVTYTVTRQNATVQGLIQGKAYFFRIAAE 10388
Query: 685 QQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSAS 744
G F TS + + T P P V E+T ++ ++W
Sbjct: 10389 NSIGMGP-----FVETSEALVIREPI----TVPERP---EDLEVKEVTKNTVTLTWNPPK 10436
Query: 745 DTVSGFRVEYELSEE--GDEPQYLDLPSTATS--VNIPDLLPGRKYIVNVYQISEDGEQS 800
+ Y L G E + S + L G Y V ++ G+
Sbjct: 10437 YDGGSEIINYVLESRLIGTEKFHKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGK 10496
Query: 801 LILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPE 860
T T D PT+ + +R A Y P V E ++ E
Sbjct: 10497 PSFCTKPITCKDELAPPTLHLDFRDKLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLE 10556
Query: 861 TANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQET---TGTPRSDTVPSPRD----L 913
+ T P I A + VV++ T G + + V P +
Sbjct: 10557 --DDRTHIKTTPATLALEKIKAKRSDSGKYCVVVENSTGSRKGFCQVNVVDRPGPPVGPV 10614
Query: 914 QFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPGEHGQRLPI---SRNTFAEVTG 966
F EVT + I W PP S +T Y ++ V +P+ S T +V+
Sbjct: 10615 SFDEVTKDYMVISWKPPLDDGGSKITNYIIEKKEVG----KDVWMPVTSASAKTTCKVSK 10670
Query: 967 LSPGVTYYFKVFAVSHGRESKPLTAQQTTKLD------APTNLQFVNETDSTVLVRWTPP 1020
L G Y F++ A + S PL + D AP T + LV W P
Sbjct: 10671 LLEGKDYIFRIHAENLYGISDPLVSDSMKAKDRFRVPDAPDQPIVTEVTKDSALVTWNKP 10730
Query: 1021 R---AQITGYRLTVGLTRRGQPRQYNVGP--SVSKYPLRNLQPASEYTVSLVA---IKGN 1072
IT Y L T + + P +K+ + +L +Y + A I
Sbjct: 10731 HDGGKPITNYILEKRETMSKRWARVTKDPIHPYTKFRVPDLLEGCQYEFRVSAENEIGIG 10790
Query: 1073 QESPKATGVFTTLQPGSSIPPYNTEVTETT---IVITWTPAPRIGFKLGVRPSQGGEAPR 1129
SP + VF PP N E +TT + +TW P PR
Sbjct: 10791 DPSPPSKPVFAKDPIAKPSPPVNPEAIDTTCNSVDLTWQP------------------PR 10832
Query: 1130 EVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTG 1189
D GS ++ Y+ Q + D + R A N E+ P+T
Sbjct: 10833 H---DGGSKILG-------YIVEYQKVGDEEWRRA--------------NHTPESCPETK 10868
Query: 1190 VLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPG---LEYNVS 1246
T +R+ G+ + H + D L P L+ N++
Sbjct: 10869 YKVTGLRDGQTYK---FRVLAVNAAGES-----DPAHVPEPVLVKDRLEPPELILDANMA 10920
Query: 1247 VYTVKDDKESVPISDT-----IIPEVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGYRIT 1301
++ + + DT II VP F +T W + RI
Sbjct: 10921 ------REQHIKVGDTLRLSAIIKGVP------FPKVT-------WKKEDRDAPTKARID 10961
Query: 1302 VVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAVPPP 1361
V G + I + G Y++T P +SV L+ PP
Sbjct: 10962 VTPVGSKLEI-RNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDKPG------------PP 11008
Query: 1362 TDLRFTNIGPDTMRVTWAPPPSID---LTNFLVRYSPVKNEEDVAELSISPSDNAVVLTN 1418
DL + I D+ +TW P +TN++V V + + + LS + + +
Sbjct: 11009 RDLEVSEIRKDSCYLTWKEPLDDGGSVITNYVVERRDVASAQ-WSPLSATSKKKSHFAKH 11067
Query: 1419 LLPGTEYVVSVSSVYEQHESTPLRGRQKT--GLDS------PTGIDFSDITANSFTVHWI 1470
L G +Y+ V++ Q+ P K LD P + D+ ++ W
Sbjct: 11068 LNEGNQYLFRVAAE-NQYGRGPFVETPKPIKALDPLHPPGPPKDLHHVDVDKTEVSLVWN 11126
Query: 1471 APR----ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN--- 1523
P + ITGY + + E + V + +T L G Y + A N
Sbjct: 11127 KPDRDGGSPITGYLVEYQEEGTQDWIKFKTVTNLE--CVVTGLQQGKTYRFRVKAENIVG 11184
Query: 1524 -GREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPV 1582
G ++ + I Q + VP +E+ L++ TVR+ I G P
Sbjct: 11185 LGLPDTTIPIECQEKL--VPPSVELDVKLIEGLVVK---AGTTVRFPAIIRGVP---VPT 11236
Query: 1583 QEFTVPGSK---------------STATISGL--KPGVDYTITVYAVTGRGDSPASSKPI 1625
++T GS+ S TI + +Y ITV + A SK +
Sbjct: 11237 AKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEYQITV-------SNAAGSKTV 11289
Query: 1626 SINYRTEIDKPSQ----MQVTDVQDNSISVKWLP----SSSPVTGYRVTT--TPKNGPGP 1675
+++ T +D P + + DV +++ W P SPV Y V T K+ G
Sbjct: 11290 AVHL-TVLDVPGPPTGPINILDVTPEHMTISWQPPKDDGGSPVINYIVEKQDTRKDTWGV 11348
Query: 1676 TKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDR------PKGL 1729
++G +T++ I LQ EYV V A+N G PL T + P
Sbjct: 11349 V---SSGSSKTKLKIPHLQKGCEYVFRVRAENKIGVGPPLDSTPTVAKHKFSPPSPPGKP 11405
Query: 1730 AFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQ----GLRP 1785
TD+ ++ ++W P+ Y + + + + A+L+ GL
Sbjct: 11406 VVTDITENAATVSWTLPKSDGGSPITGYYMERREVTGKWVRVN-KTPIADLKFRVTGLYE 11464
Query: 1786 GSEYTVSVVALH------DDMESQPLIGTQSTAIPA-PTDLKFTQVTPTSLSAQWTPP-- 1836
G+ Y V A + S P+ + P P + K + + WT P
Sbjct: 11465 GNTYEFRVFAENLAGLSKPSPSSDPIKACRPIKPPGPPINPKLKDKSRETADLVWTKPLS 11524
Query: 1837 --NVQLTGYRVRVTPKEKTGPMKEINLAP--DSSSVVVSGLMVATKYEVSVYALKDTLTS 1892
+ GY V K T IN + V GL+ +Y + A
Sbjct: 11525 DGGSPILGYVVE-CQKPGTAQWNRINKDELIRQCAFRVPGLIEGNEYRFRIKAANIVGEG 11583
Query: 1893 RP---AQGVVTTLENVSPPR-------RARVTDATETTITISWRTK-------TETITG- 1934
P A+ V+ + + PP R +T TI I R K T T G
Sbjct: 11584 EPRELAESVIAK-DILHPPEVELDVTCRDVITVRVGQTIRILARVKGRPEPDITWTKEGK 11642
Query: 1935 -----FQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVID 1989
+VD + + +Q IK VR+ Y I + +A+ S +V
Sbjct: 11643 VLVREKRVDLIQDLPRVELQ--IKEAVRA-------DHGKYIISAKNSSGHAQGSAIV-- 11691
Query: 1990 ASTAIDAP---SNLRFLATTPNSLLVSWQPP----RARITGYIIKYEKPGSPPREVVPRP 2042
+D P NL+ T + +SW+ P + IT +I++Y KP +V
Sbjct: 11692 --NVLDRPGPCQNLKVTNVTKENCTISWENPLDNGGSEITNFIVEYRKPNQKGWSIV--- 11746
Query: 2043 RPGVTEATI-TGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELPQLVTLPHPNLHGPEI 2101
VT+ I L EY V A +N P I K P L P PE
Sbjct: 11747 ASDVTKRLIKANLLANNEYYFRVCA-ENKVGVGPTIETK----TPILAINPIDRPGEPEN 11801
Query: 2102 LDVPSTVQKTPFV--THPGYDTGN 2123
L + + ++ P YD G+
Sbjct: 11802 LHIADKGKTFVYLKWRRPDYDGGS 11825
Score = 67.8 bits (164), Expect = 1e-10
Identities = 172/864 (19%), Positives = 306/864 (35%), Gaps = 155/864 (17%)
Query: 1325 VTGLEPGIDYDISVITLINGGESAPT------TLTQQTAVPPPTDLRFTNIGPDTMRVTW 1378
VT L G +Y V + G P L T PPT L T++ ++M + W
Sbjct: 19639 VTKLLKGNEYIFRVTGVNKYGVGEPLESVAIKALDPFTVPSPPTSLEITSVTKESMTLCW 19698
Query: 1379 APPPS---IDLTNFLVRYSPVKNEEDVAELSISP-SDNAVVLTNLLPGTEYVVSV----- 1429
+ P S +++ +++ KN ++ P D V T L G EY V
Sbjct: 19699 SRPESDGGSEISGYIIERRE-KNSLRWVRVNKKPVYDLRVKSTGLREGCEYEYRVYAENA 19757
Query: 1430 SSVYEQHESTPL-RGRQKTGLDS-PTGIDFSDITANSFTVHWIAP----RATITGYRIRH 1483
+ + E++PL R L S P+ D + T+ W+ P A ITGY + +
Sbjct: 19758 AGLSLPSETSPLIRAEDPVFLPSPPSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEY 19817
Query: 1484 HPEHFSGRPREDRVPHSRNS-ITLTNLTPGTEYVVSIVALN-----------------GR 1525
+ + + R + T++ LT G EYV + ++N R
Sbjct: 19818 --KKSDDTDWKTSIQSLRGTEYTISGLTTGAEYVFRVKSVNKVGASDPSDSSDPQIAKER 19875
Query: 1526 EESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEF 1585
EE PL S++ + L V A ++ + + V + + + + + +
Sbjct: 19876 EEEPLF----DIDSEMRKTLIVKAGASFTMTVPFRGRPVP----NVLWSKPDTDLRTRAY 19927
Query: 1586 T-VPGSKSTATI--SGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVT 1642
S+++ TI + YT+T+ V A+S + + P+ + V
Sbjct: 19928 VDTTDSRTSLTIENANRNDSGKYTLTIQNVLS-----AASLTLVVKVLDTPGPPTNITVQ 19982
Query: 1643 DVQDNSISVKW-LPSS---SPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVE 1698
DV S + W +P + +PV Y + + T ++ + LQ
Sbjct: 19983 DVTKESAVLSWDVPENDGGAPVKNYHIEKREASKKAWVSV-TNNCNRLSYKVTNLQEGAI 20041
Query: 1699 YVVSVYAQNPSGESQPLVQTAVTNIDR----PKGLAFTDVDVDSIKIAWESPQGQVSRYR 1754
Y V +N G P I P+ L T + DS+ + W P+
Sbjct: 20042 YYFRVSGENEFGVGIPAETKEGVKITEKPSPPEKLGVTSISKDSVSLTWLKPEHDGGSRI 20101
Query: 1755 VTY--SSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTA 1812
V Y + E G + + GLR SEY V A E+Q
Sbjct: 20102 VHYVVEALEKGQKNWVKCAVAKSTHHVVSGLRENSEYFFRVFA-----ENQ-------AG 20149
Query: 1813 IPAPTDLKFTQVTPTSLSAQWTPPNVQL-----------TGYRVRVTPKEKTGPMKEINL 1861
+ P +L + P + Q PP + + G ++V P+ ++ L
Sbjct: 20150 LSDPREL----LLPVLIKEQLEPPEIDMKNFPSHTVYVRAGSNLKVDIPISGKPLPKVTL 20205
Query: 1862 APD----------SSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGV------VTTLENV 1905
+ D ++ + L + K V+ A + +T+ + G + L+
Sbjct: 20206 SRDGVPLKATMRFNTEITAENLTINLKESVTADAGRYEITAANSSGTTKAFINIVVLDRP 20265
Query: 1906 SPPR-RARVTDATETTITISWR---------------TKTETITGFQVDAVPANGQTPIQ 1949
PP ++D TE ++T+ W K ET T AV +
Sbjct: 20266 GPPTGPVVISDITEESVTLKWEPPKYDGGSQVTNYILLKRETST-----AVWTEVSATVA 20320
Query: 1950 RTIKPDVRSYTITGLQPGTDYKIYL-----YTLNDNARSSPVVIDASTAIDAPSNLRFLA 2004
RT+ + L G +Y+ + + ++D+ S+ V + P + ++
Sbjct: 20321 RTM------MKVMKLTTGEEYQFRIKAENRFGISDHIDSACVTVKLPYTTPGPPSTPWVT 20374
Query: 2005 -TTPNSLLVSWQPP----RARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTE 2059
T S+ V W P + + GY ++ + S + + T +T + G
Sbjct: 20375 NVTRESITVGWHEPVSNGGSAVVGYHLEMKDRNSILWQKANKLVIRTTHFKVTTISAGLI 20434
Query: 2060 YTIYVIAL------KNNQKSEPLI 2077
Y V A K + SEP++
Sbjct: 20435 YEFRVYAENAAGVGKPSHPSEPVL 20458
Score = 65.1 bits (157), Expect = 8e-10
Identities = 102/477 (21%), Positives = 189/477 (39%), Gaps = 56/477 (11%)
Query: 628 IQWNAPQP---SHISKYILRWRPKNSVGRWKEAT-IPGHLNSYTIKGLKPGVVYEGQLIS 683
+ W P+ S ++ YI+ R + RW +P + Y GL G+ YE ++ +
Sbjct: 23645 LTWYPPEDDGGSQVTGYIVE-RKEVRADRWVRVNKVPVTMTRYRSTGLTEGLEYEHRVTA 23703
Query: 684 IQQYGHQEVTRFDFTTTSTSTPVTS-NTVTGETTPFSPLVATSESVTEITASSFVVSWVS 742
I G + +R S P+ + + + P +P VT+ T +S ++W
Sbjct: 23704 INARGSGKPSR-------PSKPIVAMDPIAPPGKPQNP------RVTDTTRTSVSLAWSV 23750
Query: 743 ASDT----VSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDG- 797
D V+G+ +E + ++ + + P+ + L G +Y V + G
Sbjct: 23751 PEDEGGSKVTGYLIEMQKVDQHEWTKCNTTPTKIREYTLTHLPQGAEYRFRVLACNAGGP 23810
Query: 798 -EQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWS---RPQAPITGYRI-VYSPSVEGS 852
E + + T + T PD +D+ I VR R PI G + + EG
Sbjct: 23811 GEPAEVPGTVKVTEMLEYPDYELDERYQEGIFVRQGGVIRLTIPIKGKPFPICKWTKEGQ 23870
Query: 853 STE----LNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVP 908
+ ET + + + G + +E V I+ G+P S P
Sbjct: 23871 DISKRAMIATSETHTELVIKEADRGDSGTYDL-VLENKCGKKAVYIKVRVIGSPNSPEGP 23929
Query: 909 SPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEV 964
L++ ++ V + W PP + + GY ++ V + + R T V
Sbjct: 23930 ----LEYDDIQVRSVRVSWRPPADDGGADILGYILERREVPKAAWYTIDSRV-RGTSLVV 23984
Query: 965 TGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTN--------LQFVNETDSTVLVR 1016
GL V Y+F+V A + SKPL +++ P N + ++ T S+V +
Sbjct: 23985 KGLKENVEYHFRVSAENQFGISKPLKSEEPVTPKTPLNPPEPPSNPPEVLDVTKSSVSLS 24044
Query: 1017 WTPPR----AQITGYRLTVGLTRRGQPRQYN-VGPSVSKYPLRNLQPASEYTVSLVA 1068
W+ P+ +++TGY + T + ++N + + Y + L P +EY ++A
Sbjct: 24045 WSRPKDDGGSRVTGYYIERKETSTDKWVRHNKTQITTTMYTVTGLVPDAEYQFRIIA 24101
Score = 60.1 bits (144), Expect = 3e-08
Identities = 177/822 (21%), Positives = 289/822 (35%), Gaps = 149/822 (18%)
Query: 1360 PPTDLRFTNIGPDTMRVTWAPPPS---IDLTNFLVRYSPVKNEEDVAELSISPSDNAVVL 1416
P +L T + + W P + + ++V +K + V + S V
Sbjct: 6787 PVRNLEVTETFDGEVSLAWEEPLTDGGSKIIGYVVERRDIKRKTWVLATDRAESCEFTVT 6846
Query: 1417 TNLLPGTEYVVSVSS-----VYEQHES-TPLRGRQKTGLDSPT-GIDFSDITANSFTVHW 1469
G EY+ VS+ E E+ P+ R K + P + +D+ ++ W
Sbjct: 6847 GLQKGGVEYLFRVSARNRVGTGEPVETDNPVEARSKYDVPGPPLNVTITDVNRFGVSLTW 6906
Query: 1470 IAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGR 1525
P A IT Y I + V S T+T++ G EY + R
Sbjct: 6907 EPPEYDGGAEITNYVIELRDKTSIRWDTAMTVRAEDLSATVTDVVEGQEYSFRV-----R 6961
Query: 1526 EESPLLIGQQSTVSDV------------PRDLEVVAATPTSLLISWDAP----AVTVRYY 1569
++ + +G+ S + P +L T +S+ + W+ P + Y
Sbjct: 6962 AQNRIGVGKPSAATPFVKVADPIERPSPPVNLTSSDQTQSSVQLKWEPPLKDGGSPILGY 7021
Query: 1570 RITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINY 1629
I E G ++ ++ + T ++GL+ G Y V A G S S +
Sbjct: 7022 IIERCEEGKDNWIRCNMKLVPELTYKVTGLEKGNKYLYRVSAENKAGVSDPSEILGPLTA 7081
Query: 1630 RTEIDKPSQMQVTDVQDNSISVKWLPSSS--PVTGYRVTTTPKNGPGPTKTKTAGPDQTE 1687
+P+ M ++ +D + P + P TGY P PT T G E
Sbjct: 7082 DDAFVEPT-MDLSAFKDGLEVIVPNPITILVPSTGY---------PRPTATWCFGDKVLE 7131
Query: 1688 ----MTIEGLQPTVEYVVSVYAQNPSG----ESQPLVQTAVTNID--------RPKGLAF 1731
+ ++ L E V+S ++ G + + V+T ID PK L F
Sbjct: 7132 TGDRVKMKTLSAYAELVISPSERSDKGIYTLKLENRVKTISGEIDVNVIARPSAPKELKF 7191
Query: 1732 TDVDVDSIKIAWESPQ----GQVSRY--------RVTYSSPEDGIHEL-FPAPDGEEDTA 1778
D+ DS+ + WE P ++ Y R T++ D + +L F PD
Sbjct: 7192 GDITKDSVHLTWEPPDDDGGSPLTGYVVEKREVSRKTWTKVMDFVTDLEFTVPD------ 7245
Query: 1779 ELQGLRPGSEYTVSVVALHDDMESQPL-------IGTQSTAIPAPTDLKFTQVTPTSLSA 1831
L G EY V A + +P + T +T P ++K+ T S+
Sbjct: 7246 ----LVQGKEYLFKVCARNKCGPGEPAYVDEPVNMSTPATVPDPPENVKWRDRTANSIFL 7301
Query: 1832 QWTPP----NVQLTGYRVRVTPKEKTGPMKEINLAPD--SSSVVVSGLMVATKYEVSVYA 1885
W PP ++ GY V P+ G K + + + V+GL Y V A
Sbjct: 7302 TWDPPKNDGGSRIKGYIVERCPR---GSDKWVACGEPVAETKMEVTGLEEGKWYAYRVKA 7358
Query: 1886 LKDTLTSRPAQGVVTTLENVSPPRRARVTDATETT-----------ITISWRTKTE---T 1931
L S+P++ P + D E +T+ TK E T
Sbjct: 7359 LNRQGASKPSR----------PTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPAT 7408
Query: 1932 ITGFQVDAVPANGQTPIQRTIKPDVR----------SYTITGLQPGTDYKIYLYTLNDNA 1981
+TG P T +K D R + TI + + +N
Sbjct: 7409 VTG---KPEPKITWTKADMILKQDKRITIENVPKKSTVTIVDSKRSDTGTYIIEAVNVCG 7465
Query: 1982 RSSPVV-IDASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPR 2036
R++ VV ++ P+ T S L++W PPR ++IT Y+++ S
Sbjct: 7466 RATAVVEVNVLDKPGPPAAFDITDVTNESCLLTWNPPRDDGGSKITNYVVERRATDS--- 7522
Query: 2037 EVVPRPRPGV--TEATITGLEPGTEYTIYVIALKNNQKSEPL 2076
EV + V T T L P EY V A EP+
Sbjct: 7523 EVWHKLSSTVKDTNFKATKLIPNKEYIFRVAAENMYGVGEPV 7564
Score = 58.9 bits (141), Expect = 6e-08
Identities = 325/1703 (19%), Positives = 588/1703 (34%), Gaps = 267/1703 (15%)
Query: 611 PVEVFITETPSQP-----------NSHPIQWNAPQPS---HISKYILRWRPKNSVGRWKE 656
P+ V PS+P +S + W+ P+ + I+ Y + R + S WK
Sbjct: 21343 PITVITLGPPSKPKGPIRFDEIKADSVILSWDVPEDNGGGEITCYSIEKR-ETSQTNWKM 21401
Query: 657 ATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETT 716
++ + L Y+ ++ + +YG S P+ S+ + +
Sbjct: 21402 VCSSVARTTFKVPNLVKDAEYQFRVRAENRYG-------------VSQPLVSSIIVAKHQ 21448
Query: 717 PFSPLVATSESVTEITASSFVVSW----VSASDTVSGFRVEYELSEEGDEPQYLDLPSTA 772
P + +T+ ++W V+GF VE + + P +
Sbjct: 21449 FRIPGPPGKPVIYNVTSDGMSLTWDAPVYDGGSEVTGFHVEKKERNSILWQKVNTSPISG 21508
Query: 773 TSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDP--TVDQVDDT--SIV 828
L+ G Y VY + G S S+ T +P DP T D +D T +I
Sbjct: 21509 REYRATGLVEGLDYQFRVYAENSAGLSSPS-DPSKFTLAVSPVDPPGTPDYIDVTRETIT 21567
Query: 829 VRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETAN-SVTLSDLQPGVQYNITIYA- 882
++W+ P + I GY I E N + + T++ L PG +Y I A
Sbjct: 21568 LKWNPPLRDGGSKIVGYSIEKRQGNE-RWVRCNFTDVSECQYTVTGLSPGDRYEFRIIAR 21626
Query: 883 -----VEENQESTPVVIQQETTGTPRSDTVPSPRD---LQFVEVTDVKVTIMWTPPESAV 934
+ +S+ +++ ++ P + P D ++ E +K + P V
Sbjct: 21627 NAVGTISPPSQSSGIIMTRDENVPPIVEFGPEYFDGLIIKSGESLRIKALVQGRPVPR-V 21685
Query: 935 TGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFK--------VFAVSHGRES 986
T ++ V I + E+T + + + + V+ V S
Sbjct: 21686 TWFKDGV-------------EIEKRMNMEITDVLGSTSLFVRDATRDHRGVYTVEAKNAS 21732
Query: 987 KPLTAQQTTKL-DAPTN----LQFVNETDSTVLVRWTPPR----AQITGYRLTVGLTRRG 1037
A+ K+ D P ++F N T + + W P A IT Y + T R
Sbjct: 21733 GSAKAEIKVKVQDTPGKVVGPIRFTNITGEKMTLWWDAPLNDGCAPITHYIIEKRETSRL 21792
Query: 1038 QPRQYNVGPSVSKYPLRNLQPASEYTVSLVAI------KGNQESPKATGVFTTLQPGSSI 1091
Y L +EY + A+ + P + T+ I
Sbjct: 21793 AWALIEDKCEAQSYTAIKLINGNEYQFRVSAVNKFGVGRPLDSDPVVAQIQYTVPDAPGI 21852
Query: 1092 PPYNTEVTETTIVITWTPAPRIG------FKLGVRPSQGGEAPREVTSDSGS---IVVSG 1142
P + +T +I +TW G + L R + + ++ S V+G
Sbjct: 21853 PE-PSNITGNSITLTWARPESDGGSEIQQYILERREKKSTRWVKVISKRPISETRFKVTG 21911
Query: 1143 LTPGVEYVYTIQVLRDGQERDAPIVNKVVT---PLSPPTNLHLEANPDTGVLTVSWERST 1199
LT G EY + + A +++++ P++PP + DT TVS E S
Sbjct: 21912 LTEGNEYEFHVMAENAAGVGPASGISRLIKCREPVNPPGPPTVVKVTDTSKTTVSLEWSK 21971
Query: 1200 TP-----DITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKD-- 1252
+I GY I + + + ++ T +L G EY V +
Sbjct: 21972 PVFDGGMEIIGYIIEMCKADLGDWHKVNAEACV-KTRYTVTDLQAGEEYKFRVSAINGAG 22030
Query: 1253 DKESVPISDTI-------IPEVPQLTDLSFVDITDSSIGLR--------------WTPLN 1291
+S ++ TI PE+ + + + +R W+ +
Sbjct: 22031 KGDSCEVTGTIKAVDRLTAPELDIDANFKQTHVVRAGASIRLFIAYQGRPTPTAVWSKPD 22090
Query: 1292 SSTIIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTT 1351
S+ + I + + + E+ + G YT+T + +G +S T
Sbjct: 22091 SNLSLRADIHTTDSFSTLTV-ENCNRNDAGKYTLT------------VENNSGSKSITFT 22137
Query: 1352 LTQQTAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAE---LSIS 1408
+ PP + F ++ + + W P +D + Y K E +S
Sbjct: 22138 VKVLDTPGPPGPITFKDVTRGSATLMW-DAPLLDGGARIHHYVVEKREASRRSWQVISEK 22196
Query: 1409 PSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDS----PTGIDFSDITANS 1464
+ + +L G Y VS+V E P + P +D D + +S
Sbjct: 22197 CTRQIFKVNDLAEGVPYYFRVSAVNEYGVGEPYEMPEPIVATEQPAPPRRLDVVDTSKSS 22256
Query: 1465 FTVHWIAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRN-SITLTNLTPGTEYVVSI 1519
+ W+ P + ITGY + + G H++ + T+ L TEY +
Sbjct: 22257 AVLAWLKPDHDGGSRITGYLLEMRQK---GSDFWVEAGHTKQLTFTVERLVEKTEYEFRV 22313
Query: 1520 VALNGREESPLLIGQQSTVSDVPR-----DLEVV--------AATPTSL---LISWDAPA 1563
A N S S + P+ DL + A +P ++ + AP
Sbjct: 22314 KAKNDAGYSEPREAFSSVIIKEPQIEPTADLTGITNQLITCKAGSPFTIDVPISGRPAPK 22373
Query: 1564 VTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVD--YTITVYAVTGRGDSPAS 1621
VT + + ET S T ++T T+ G Y +T+ ++ A
Sbjct: 22374 VTWKLEEMRLKETDRVS----ITTTKDRTTLTVKDSMRGDSGRYFLTL-------ENTAG 22422
Query: 1622 SKPISINYRTEIDKPSQM----QVTDVQDNSISVKWLP----SSSPVTGYRVTTTPKNGP 1673
K S+ I +P + +V+ V S + W + +T Y + ++G
Sbjct: 22423 VKTFSVTV-VVIGRPGPVTGPIEVSSVSAESCVLSWGEPKDGGGTEITNY-IVEKRESGT 22480
Query: 1674 GPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAV------TNIDRPK 1727
+ + +T++ + L +EY V ++N G S+PL + P
Sbjct: 22481 TAWQLVNSSVKRTQIKVTHLTKYMEYSFRVSSENRFGVSKPLESAPIIAEHPFVPPSAPT 22540
Query: 1728 GLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGE----EDTAELQGL 1783
V +++ I WE P + Y + + + + + E ++ GL
Sbjct: 22541 RPEVYHVSANAMSIRWEEPYHDGGSKIIGYWVEKKERNTILWVKENKVPCLECNYKVTGL 22600
Query: 1784 RPGSEYTVSVVALH------DDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPP- 1836
G EY AL+ S+P++ + AP + T VT +++S W+ P
Sbjct: 22601 VEGLEYQFRTYALNAAGVSKASEASRPIMA--QNPVDAPGRPEVTDVTRSTVSLIWSAPA 22658
Query: 1837 ---NVQLTGYRVRVTPKEKTGP---MKEINLAPDSSSVVVSGLMVATKYEVSVYALKDT- 1889
++ GY + P + G +K + V+ L YE V A
Sbjct: 22659 YDGGSKVVGYIIERKPVSEVGDGRWLKCNYTIVSDNFFTVTALSEGDTYEFRVLAKNAAG 22718
Query: 1890 LTSRPAQ--GVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVP------ 1941
+ S+ ++ G VT + +PP+ DA ++ R ++ + V P
Sbjct: 22719 VISKGSESTGPVTCRDEYAPPKAE--LDARLHGDLVTIRAGSDLVLDAAVGGKPEPKIIW 22776
Query: 1942 ANGQTPIQRTIKPDV-----RSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDA 1996
G + K + R+ + +D Y T+ NA + V +D+
Sbjct: 22777 TKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSGKYTLTVK-NASGTKAVSVMVKVLDS 22835
Query: 1997 P---SNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREVVPRPRPGVTEA 2049
P L T ++W P+ A IT YI++ + +V P ++
Sbjct: 22836 PGPCGKLTVSRVTQEKCTLAWSLPQEDGGAEITHYIVERRETSRLNWVIVEGECPTLS-Y 22894
Query: 2050 TITGLEPGTEYTIYVIALKN-----NQKSEPLIGRKKTDELPQLVTLPHPNLHGPEILDV 2104
+T L EY V A+ +SEP++ R T+P P P I +
Sbjct: 22895 VVTRLIKNNEYIFRVRAVNKYGPGVPVESEPIVARNS-------FTIPSP----PGIPEE 22943
Query: 2105 PSTVQKTPFV--THPGYDTGNGI 2125
T ++ + T P D GN I
Sbjct: 22944 VGTGKEHIIIQWTKPESDGGNEI 22966
Score = 55.5 bits (132), Expect = 7e-07
Identities = 128/535 (23%), Positives = 202/535 (37%), Gaps = 90/535 (16%)
Query: 593 GIGEWHCQPLQTYPSSSGPVEVFITETPSQP-------NSHPIQWNAPQ---PSHISKYI 642
GIGE PL + P ++ + + P +P NS + W P+ S ++ Y
Sbjct: 9993 GIGE----PLDSEPETARNL-FSVPGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPVTGYW 10047
Query: 643 LRWRPKNSVGRWK-------EATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRF 695
L + S RWK +A G SY + GL G Y+ ++ +I G +
Sbjct: 10048 LEMKDTTSK-RWKRVNRDPIKAMTLGV--SYKVTGLIEGSDYQFRVYAINAAGVGPASL- 10103
Query: 696 DFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWV----SASDTVSGFR 751
S P T+ P +P VT+ T SS + W V+G+
Sbjct: 10104 ------PSDPATARD------PIAPPGPPFPKVTDWTKSSADLEWSPPLKDGGSKVTGYI 10151
Query: 752 VEYELSEEGDEP--QYLDLPSTATSVNIPDLLPGRKY-----IVNVYQISEDGEQSLILS 804
VEY+ EEG E + D T + + L G Y VN+ I E GE + ++
Sbjct: 10152 VEYK--EEGKEEWEKGKDKEVRGTKLVVTGLKEGAFYKFRVRAVNIAGIGEPGEVTDVIE 10209
Query: 805 TSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETA-- 862
PD +D IVV I P+V + E LP+ A
Sbjct: 10210 MKDRLVS---PDLQLDASVRDRIVVHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEATI 10266
Query: 863 ------NSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFV 916
+S+ + + Q Q ++ A E E +I VP P F+
Sbjct: 10267 ETTAISSSMVIKNCQRSHQGVYSLLAKNEAGERKKTIIVDVLD-------VPGPVGTPFL 10319
Query: 917 --EVTDVKVTIMWTPPE----SAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPG 970
+T+ + W PE S +T Y ++ + ++R A V GL G
Sbjct: 10320 AHNLTNESCKLTWFSPEDDGGSPITNYVIEKRESDRRAWTPVTYTVTRQN-ATVQGLIQG 10378
Query: 971 VTYYFKVFA---VSHG---RESKPLTAQQT-TKLDAPTNLQFVNETDSTVLVRWTPPR-- 1021
Y+F++ A + G S+ L ++ T + P +L+ T +TV + W PP+
Sbjct: 10379 KAYFFRIAAENSIGMGPFVETSEALVIREPITVPERPEDLEVKEVTKNTVTLTWNPPKYD 10438
Query: 1022 --AQITGYRLTVGLTRRGQPRQYNVGPSVS-KYPLRNLQPAS--EYTVSLVAIKG 1071
++I Y L L + + +S KY ++ L+ EY VS V I G
Sbjct: 10439 GGSEIINYVLESRLIGTEKFHKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVG 10493
Score = 52.8 bits (125), Expect = 4e-06
Identities = 80/336 (23%), Positives = 120/336 (35%), Gaps = 46/336 (13%)
Query: 602 LQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQP---SHISKYILRWRPKN-SVGRWKEA 657
++ Y S P + +T+ ++ S + W+AP S I+ Y++ R + W+E
Sbjct: 9187 VEVYDRPSPPRNLAVTDIKAE--SCYLTWDAPLDNGGSEITHYVIDKRDASRKKAEWEEV 9244
Query: 658 TIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTP 717
T Y I L P YE ++ ++ +YG + + D V + P
Sbjct: 9245 TNTAVEKRYGIWKLIPNGQYEFRVRAVNKYGISDECKSD-------KVVIQDPYRLPGPP 9297
Query: 718 FSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTA----- 772
P V T S +VSW D Y L + + Y S A
Sbjct: 9298 GKPKVLAR------TKGSMLVSWTPPLDNGGSPITGYWLEKREEGSPYWSRVSRAPITKV 9351
Query: 773 ----TSVNIPDLLPGRKY-----IVNVYQISEDGEQSLILSTSQTTAPDAPPD-PTVDQV 822
N+P LL G KY +N I E S P PP P V
Sbjct: 9352 GLKGVEFNVPRLLEGVKYQFRAMAINAAGIGPPSEPSDPEVAGDPIFPPGPPSCPEVKDK 9411
Query: 823 DDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPE---TANSVTLSDLQPGVQ 875
+SI + W P +PI GY + +N P+ T + +L+ +
Sbjct: 9412 TKSSISLGWKPPAKDGGSPIKGYIVEMQEEGTTDWKRVNEPDKLITTCECVVPNLKELRK 9471
Query: 876 YNITIYAVEENQESTPVVIQQETTG-TPRSDTVPSP 910
Y + AV E ES P +TTG P +D P
Sbjct: 9472 YRFRVKAVNEAGESEP----SDTTGEIPATDIQEEP 9503
Score = 50.4 bits (119), Expect = 2e-05
Identities = 182/937 (19%), Positives = 327/937 (34%), Gaps = 131/937 (13%)
Query: 1277 DITDSSIGLRWTPLNS---STIIGYRITV-VAAGEGIPIFEDFVDSSVGYYTVTGLEPGI 1332
DIT+++ + WT S S I GY + G+ + + + + + VTGL G
Sbjct: 11409 DITENAATVSWTLPKSDGGSPITGYYMERREVTGKWVRVNKTPIADLK--FRVTGLYEGN 11466
Query: 1333 DYDISVITLINGGESAPTTLTQQTAV-------PPPTDLRFTNIGPDTMRVTWAPPPSID 1385
Y+ V G S P+ + PP + + + +T + W P S D
Sbjct: 11467 TYEFRVFAENLAGLSKPSPSSDPIKACRPIKPPGPPINPKLKDKSRETADLVWTKPLS-D 11525
Query: 1386 LTNFLVRYSPVKNEEDVAELSISPSDN-----AVVLTNLLPGTEYVVSVSSVYEQHESTP 1440
+ ++ Y + A+ + D A + L+ G EY + + E P
Sbjct: 11526 GGSPILGYVVECQKPGTAQWNRINKDELIRQCAFRVPGLIEGNEYRFRIKAANIVGEGEP 11585
Query: 1441 LRGRQKT---GLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRV 1497
+ + P ++ D+T + I R++ PE +E +V
Sbjct: 11586 RELAESVIAKDILHPPEVEL-DVTCRDVITVRVGQTIRILA-RVKGRPEPDITWTKEGKV 11643
Query: 1498 PHSRNSITLTNLTPGTE-------------YVVSIVALNGREESPLLIGQQSTVSDVP-- 1542
+ L P E Y++S +G + ++ V D P
Sbjct: 11644 LVREKRVDLIQDLPRVELQIKEAVRADHGKYIISAKNSSGHAQGSAIVN----VLDRPGP 11699
Query: 1543 -RDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISG--- 1598
++L+V T + ISW+ P + G + + + E+ P K + ++
Sbjct: 11700 CQNLKVTNVTKENCTISWENP--------LDNGGSEITNFIVEYRKPNQKGWSIVASDVT 11751
Query: 1599 -------LKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQ---MQVTDVQDNS 1648
L +Y V A G P I ID+P + + + D
Sbjct: 11752 KRLIKANLLANNEYYFRVCAENKVGVGPTIETKTPILAINPIDRPGEPENLHIADKGKTF 11811
Query: 1649 ISVKW----LPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVY 1704
+ +KW SP Y V K + +T ++ Y V
Sbjct: 11812 VYLKWRRPDYDGGSPNLSYHVERRLKGSDDWERVHKGSIKETHYMVDRCVENQIYEFRVQ 11871
Query: 1705 AQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSI-------KIAWESPQGQVSRYRVTY 1757
+N GES V+T + D+ + + I E+ V +
Sbjct: 11872 TKNEGGESD-WVKTEEVVVKEDLQKPVLDLKLSGVLTVKAGDTIRLEAGVRGKPFPEVAW 11930
Query: 1758 SSPEDGIHELFPAP----DGEEDTAELQGLRP----GSEYTVSVVALHDDMESQPLIGTQ 1809
+ +D +L +P D D+++ + G +Y V+ + +
Sbjct: 11931 TKDKDAT-DLTRSPRVKIDTRADSSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATVNVL 11989
Query: 1810 STAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVV 1869
P +LK V+ + W PP G ++ EK K + + S++V+
Sbjct: 11990 DKPGPV-RNLKIVDVSSDRCTVCWDPPEDD-GGCEIQNYILEKC-ETKRMVWSTYSATVL 12046
Query: 1870 VSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENV---------SPPRRARVTDATETT 1920
G V E + Y + ++ G T + V P VT ++
Sbjct: 12047 TPGTTVTRLIEGNEYIFRVRAENKIGTGPPTESKPVIAKTKYDKPGRPDPPEVTKVSKEE 12106
Query: 1921 ITISWRTKT----ETITGFQVDAVPANGQ--TPIQRTIKPDVRSYTITGLQPGTDYKIYL 1974
+T+ W ++ITG+ ++ + P+ ++ P+ R + L P +Y+ +
Sbjct: 12107 MTVVWNPPEYDGGKSITGYFLEKKEKHSTRWVPVNKSAIPE-RRMKVQNLLPDHEYQFRV 12165
Query: 1975 YTLND------NARSSPVVI-DASTAIDAPSNLRFLATTPNSLLVSWQPP----RARITG 2023
N+ + S PVV D P+N R + TT +S+ + W P A I G
Sbjct: 12166 KAENEIGIGEPSLPSRPVVAKDPIEPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAPIIG 12225
Query: 2024 YIIKYEK--PGSPPREVVPRPRPGV----TEATITGLEPGTEYTIYVIALKNNQKSEPLI 2077
Y+++ + P E R E T+T L+ EY V A NQ +
Sbjct: 12226 YVVEMRPKIADASPDEGWKRCNAAAQLVRKEFTVTSLDENQEYEFRVCA--QNQ-----V 12278
Query: 2078 GRKKTDELPQLVTLPHPNLHGPEILDVPSTVQKTPFV 2114
G + EL + + P L PEI D+ ++++K V
Sbjct: 12279 GIGRPAELKEAIK-PKEILEPPEI-DLDASMRKLVIV 12313
Score = 48.5 bits (114), Expect = 8e-05
Identities = 107/537 (19%), Positives = 187/537 (34%), Gaps = 65/537 (12%)
Query: 610 GPVEVFITETPSQPNSHPIQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSY 666
GPV ++ + H + W P+ S ++ YI+ R + W T S+
Sbjct: 12395 GPVSDLKVSDVTKTSCH-VSWAPPENDGGSQVTHYIVEKREADRK-TWSTVTPEVKKTSF 12452
Query: 667 TIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSE 726
+ L PG Y ++ ++ +YG T PV ++ E P L
Sbjct: 12453 HVTNLVPGNEYYFRVTAVNEYG-------PGVPTDVPKPVLASDPLSEPDPPRKL----- 12500
Query: 727 SVTEITASSFVVSWV----SASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLP 782
VTE+T +S ++W+ + G+ Y E+ + S+ + L
Sbjct: 12501 EVTEMTKNSATLAWLPPLRDGGAKIDGYITSYREEEQPADRWTEYSVVKDLSLVVTGLKE 12560
Query: 783 GRKY-----IVNVYQISEDGEQSLILSTSQTTAPD---APPDPTVDQVDDTSIVVRWSRP 834
G+KY N +S E + + P P T+ I
Sbjct: 12561 GKKYKFRVAARNAVGVSLPREAEGVYEAKEQLLPPKILMPEQITIKAGKKLRIEAHVYGK 12620
Query: 835 QAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDL--QPGVQYNITIYAVEENQESTPV 892
P ++ V S ++ ++++ + + D+ + Y++T
Sbjct: 12621 PHPTCKWKKGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIK 12680
Query: 893 VIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPG 948
V+ + G P+ P D+ ++ ++ W P S +T Y V+ V+ G
Sbjct: 12681 VVVMDAPGPPQ-----PPFDISDIDAD--ACSLSWHIPLEDGGSNITNYIVEKCDVS-RG 12732
Query: 949 EHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKL------DAPTN 1002
+ L T V L PG Y F+V A + S+PLT+ + P N
Sbjct: 12733 DWVTALASVTKTSCRVGKLIPGQEYIFRVRAENRFGISEPLTSPKMVAQFPFGVPSEPKN 12792
Query: 1003 LQFVNETDSTVLVRWTPPRAQ----ITGYRLTVGLTRRGQPRQYNVGPSV---SKYPLRN 1055
+ + V W P + I GY + R ++ ++YP
Sbjct: 12793 ARVTKVNKDCIFVAWDRPDSDGGSPIIGY--LIERKERNSLLWVKANDTLVRSTEYPCAG 12850
Query: 1056 LQPASEYTVSLVAIKGNQESP--KATGVFTTLQPGSSIPPYNTE---VTETTIVITW 1107
L EY+ + A+ SP K T T P PP E VT++T+ + W
Sbjct: 12851 LVEGLEYSFRIYALNKAGSSPPSKPTEYVTARMPVD--PPGKPEVIDVTKSTVSLIW 12905
Score = 47.4 bits (111), Expect = 2e-04
Identities = 68/293 (23%), Positives = 108/293 (36%), Gaps = 33/293 (11%)
Query: 730 EITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQY----LDLPSTATSVNIPDLLPGRK 785
+I S VSW +D + Y L E + P+ +D TS+ + L +
Sbjct: 23934 DIQVRSVRVSWRPPADDGGADILGYIL-ERREVPKAAWYTIDSRVRGTSLVVKGLKENVE 23992
Query: 786 YIVNVYQISEDGEQSLILSTSQTTA-----PDAPPD--PTVDQVDDTSIVVRWSRPQ--- 835
Y V ++ G + S T P PP P V V +S+ + WSRP+
Sbjct: 23993 YHFRVSAENQFGISKPLKSEEPVTPKTPLNPPEPPSNPPEVLDVTKSSVSLSWSRPKDDG 24052
Query: 836 -APITGYRIVYSPSVEGSSTELNLPE-TANSVTLSDLQPGVQYNITIYAV------EENQ 887
+ +TGY I + N + T T++ L P +Y I A E +
Sbjct: 24053 GSRVTGYYIERKETSTDKWVRHNKTQITTTMYTVTGLVPDAEYQFRIIAQNDVGLSETSP 24112
Query: 888 ESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIP 943
S PVV + D P +L+ + ++ VT+ W PE + GY V+
Sbjct: 24113 ASEPVVCKDPF------DKPSQPGELEILSISKDSVTLQWEKPECDGGKEILGYWVEYRQ 24166
Query: 944 VNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTK 996
++ + GL Y F+VFA + S+P + K
Sbjct: 24167 SGDSAWKKSNKERIKDKQFTIGGLLEATEYEFRVFAENETGLSRPRRTAMSIK 24219
Score = 43.9 bits (102), Expect = 0.002
Identities = 50/204 (24%), Positives = 83/204 (40%), Gaps = 22/204 (10%)
Query: 717 PFSPLVATSESVTEITASSFVVSWVSASDT----VSGFRVEYELSEEGDEPQYLDLPSTA 772
P P+V + + +S V+SW +D ++ + VE ++EG E Q + +
Sbjct: 24421 PTGPIV-----IEALLKNSAVISWKPPADDGGSWITNYVVEKCEAKEGAEWQLVSSAISV 24475
Query: 773 TSVNIPDLLPGRKYIV-----NVYQISEDGE-QSLILSTSQTTAPDAPPDPTVDQVDDTS 826
T+ I +L Y N + IS+ E S+++ S P AP PT+ V S
Sbjct: 24476 TTCRIVNLTENAGYYFRVSAQNTFGISDPLEVSSVVIIKSPFEKPGAPGKPTITAVTKDS 24535
Query: 827 IVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSV-TLSDLQPGVQYNITIY 881
VV W P A I Y + + + E +V ++ +L G++Y +
Sbjct: 24536 CVVAWKPPASDGGAKIRNYYLEKREKKQNKWISVTTEEIRETVFSVKNLIEGLEYEFRVK 24595
Query: 882 AVEENQESTPVVIQQETTGTPRSD 905
ES I + TP+SD
Sbjct: 24596 CENLGGESEWSEISEPI--TPKSD 24617
Score = 41.2 bits (95), Expect = 0.013
Identities = 92/413 (22%), Positives = 157/413 (38%), Gaps = 51/413 (12%)
Query: 1376 VTWAPPPSID---LTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSV 1432
++W PP +TN++V K + +S + S + NL Y VS+
Sbjct: 24437 ISWKPPADDGGSWITNYVVEKCEAKEGAEWQLVSSAISVTTCRIVNLTENAGYYFRVSAQ 24496
Query: 1433 YEQHESTPLRGRQKTGLDSPTGID-------FSDITANSFTVHWIAPRATITGYRIRHHP 1485
S PL + SP + +T +S V W P A+ G +IR++
Sbjct: 24497 NTFGISDPLEVSSVVIIKSPFEKPGAPGKPTITAVTKDSCVVAW-KPPASDGGAKIRNYY 24555
Query: 1486 EHFSGRPREDRVPHSRNSITLT-----NLTPGTEYVVSIVA--LNGREESPLLIGQQSTV 1538
+ + + + I T NL G EY + L G E + +
Sbjct: 24556 LEKREKKQNKWISVTTEEIRETVFSVKNLIEGLEYEFRVKCENLGGESEWSEISEPITPK 24615
Query: 1539 SDVP----------RDLEVVAATPTSLLISWDA-PAVTVRYYRITYGET----GGNSPVQ 1583
SDVP R+L V + +L+ P V++YR G+ G +Q
Sbjct: 24616 SDVPIQAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYR--QGKEIIADGLKYRIQ 24673
Query: 1584 EFTVPGSKSTATISGLKPGVDYTITVYAV--TGRGDSPASSKPISINYRTEIDKPSQMQ- 1640
EF G I+ + D TVY V T +G S + + + + +I P ++
Sbjct: 24674 EFK--GGYHQLIIASV---TDDDATVYQVRATNQGGSVSGTASLEVEVPAKIHLPKTLEG 24728
Query: 1641 ---VTDVQDNSISVKWLPSSS---PVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQ 1694
V ++ +S+K +P S PV ++ + G + + + G++
Sbjct: 24729 MGAVHALRGEVVSIK-IPFSGKPDPVITWQKGQDLIDNNGHYQVIVTRSFTSLVFPNGVE 24787
Query: 1695 PTVEYVVSVYAQNPSGESQPLVQTAVTNI-DRPKGLAFTDVDVDSIKIAWESP 1746
V A+N G Q V+ V ++ D P+G+ +DV DS+ + W P
Sbjct: 24788 RKDAGFYVVCAKNRFGIDQKTVELDVADVPDPPRGVKVSDVSRDSVNLTWTEP 24840
Score = 37.7 bits (86), Expect = 0.14
Identities = 36/131 (27%), Positives = 53/131 (40%), Gaps = 8/131 (6%)
Query: 894 IQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPVNLPGE 949
I Q+T +D PR ++ +V+ V + WT P S +T Y V+ E
Sbjct: 24804 IDQKTVELDVADVPDPPRGVKVSDVSRDSVNLTWTEPASDGGSKITNYIVEKCATT--AE 24861
Query: 950 HGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQ--TTKLDAPTNLQFVN 1007
R+ +R T V L +Y F+V A + SKP + TK D + +
Sbjct: 24862 RWLRVGQARETRYTVINLFGKTSYQFRVIAENKFGLSKPSEPSEPTITKEDKTRAMNYDE 24921
Query: 1008 ETDSTVLVRWT 1018
E D T V T
Sbjct: 24922 EVDETREVSMT 24932
Score = 35.0 bits (79), Expect = 0.92
Identities = 38/169 (22%), Positives = 71/169 (42%), Gaps = 17/169 (10%)
Query: 1610 YAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWL-PSS---SPVTGYRV 1665
Y V + K + ++ D P ++V+DV +S+++ W P+S S +T Y V
Sbjct: 24794 YVVCAKNRFGIDQKTVELDVADVPDPPRGVKVSDVSRDSVNLTWTEPASDGGSKITNYIV 24853
Query: 1666 TTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPL--VQTAVTNI 1723
+ A +T T+ L Y V A+N G S+P + +T
Sbjct: 24854 EKCATTAERWLRVGQA--RETRYTVINLFGKTSYQFRVIAENKFGLSKPSEPSEPTITKE 24911
Query: 1724 DRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPD 1772
D+ + + + D +VD + +VS + ++SS ++ + A D
Sbjct: 24912 DKTRAMNY-DEEVDETR--------EVSMTKASHSSTKELYEKYMIAED 24951
>gi|110349713 titin isoform novex-1 [Homo sapiens]
Length = 27051
Score = 175 bits (443), Expect = 6e-43
Identities = 375/1615 (23%), Positives = 611/1615 (37%), Gaps = 226/1615 (13%)
Query: 630 WNAPQPSHISK---YILRWRPKNSVG--RWKEA--TIPGHLNSYTIKGLKPGVVYEGQLI 682
W+AP SK YI+ +P + VG RW + TI N +T+ L G YE +++
Sbjct: 22587 WSAPAYDGGSKVVGYIIERKPVSEVGDGRWLKCNYTIVSD-NFFTVTALSEGDTYEFRVL 22645
Query: 683 SIQQYGHQEVTRFDFTTTSTST-PVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWV 741
+ G + S ST PVT + VT S V+
Sbjct: 22646 AKNAAGV-------ISKGSESTGPVTCRDEYAPPKAELDARLHGDLVTIRAGSDLVL--- 22695
Query: 742 SASDTVSGFRVEYELS-EEGDEP---------QYLDLPSTATSVNIPDLLPGRKYIVNVY 791
D G + E ++ +GD+ QY +TA + D KY + V
Sbjct: 22696 ---DAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAV-IKFCDRSDSGKYTLTVK 22751
Query: 792 QISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ----APITGYRIVYSP 847
S G +++ + +P TV +V + WS PQ A IT Y +
Sbjct: 22752 NAS--GTKAVSVMVKVLDSPGPCGKLTVSRVTQEKCTLAWSLPQEDGGAEITHYIVERRE 22809
Query: 848 S-------VEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG 900
+ VEG L S ++ L +Y + AV + PV + E
Sbjct: 22810 TSRLNWVIVEGECPTL-------SYVVTRLIKNNEYIFRVRAVNKYGPGVPV--ESEPIV 22860
Query: 901 TPRSDTVPSPRDL-QFVEVTDVKVTIMWTPPES----AVTGYRVDVIPV-NLPGEHGQRL 954
S T+PSP + + V + I WT PES ++ Y VD +L +
Sbjct: 22861 ARNSFTIPSPPGIPEEVGTGKEHIIIQWTKPESDGGNEISNYLVDKREKKSLRWTRVNKD 22920
Query: 955 PISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNL-------QFVN 1007
+ +T +VT L G Y F+V AV+ S+P A P+ + V+
Sbjct: 22921 YVVYDTRLKVTSLMEGCDYQFRVTAVNAAGNSEPSEASNFISCREPSYTPGPPSAPRVVD 22980
Query: 1008 ETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSV--SKYPLRNLQPASE 1061
T ++ + WT P I GY L + Q + + ++ +++ + +L+ +
Sbjct: 22981 TTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDTDQWYRVHTNATIRNTEFTVPDLKMGQK 23040
Query: 1062 YT--VSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGV 1119
Y+ V+ V +KG E ++ ++P I + E+ + + T R G L +
Sbjct: 23041 YSFRVAAVNVKGMSEYSES---IAEIEPVERIEIPDLELADD---LKKTVTIRAGASLRL 23094
Query: 1120 RPSQGGEAPREVT-----SDSGSIVVSGLTPGVEYV------------YTIQVLRDGQER 1162
S G P +T D S + T + YTI+ ++
Sbjct: 23095 MVSVSGRPPPVITWSKQGIDLASRAIIDTTESYSLLIVDKVNRYDAGKYTIEAENQSGKK 23154
Query: 1163 DAPIVNKVV-TPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSL 1221
A ++ KV TP P+ E + D+ +T++WE P I G P N
Sbjct: 23155 SATVLVKVYDTPGPCPSVKVKEVSRDS--VTITWE---IPTIDG----GAPVNNYIVEKR 23205
Query: 1222 EEVVHA-----DQSSCTFDNLSPGLEYNVSVYTVKDDK-----ESVPISDTI-IPEVPQL 1270
E + A + S T +S +E + + V + E SD + + EVP +
Sbjct: 23206 EAAMRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYGIGEPCETSDAVLVSEVPLV 23265
Query: 1271 -TDLSFVDITDSSIGLRW-TPL--NSSTIIGYRITVVAAGEGIPIFEDFVDSSVGYYTVT 1326
L VD+T S++ L W PL S + GY + AG + + +V +TVT
Sbjct: 23266 PAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGTERWMKVVTLKPTVLEHTVT 23325
Query: 1327 GLEPGIDYDISVITLINGGESAP----TTLT-QQTAVPPPTDLRFTNIGPDTMRV----- 1376
L G Y + G S P T +T Q V P DL + + T+ V
Sbjct: 23326 SLNEGEQYLFRIRAQNEKGVSEPRETVTAVTVQDLRVLPTIDL--STMPQKTIHVPAGRP 23383
Query: 1377 -------TWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSV 1429
PPP+ F ++E E + + T + EY + +
Sbjct: 23384 VELVIPIAGRPPPAASW--FFAGSKLRESERVTVETHTKVAKLTIRETTIRDTGEYTLEL 23441
Query: 1430 SSVY-EQHESTPLRGRQKTGLDSPTG-IDFSDITANSFTVHWIAPR----ATITGYRIRH 1483
+V E+ + K G PTG I +I A S T+ W P A ++GY +
Sbjct: 23442 KNVTGTTSETIKVIILDKPG--PPTGPIKIDEIDATSITISWEPPELDGGAPLSGYVVEQ 23499
Query: 1484 HPEHFSG-RPREDRVPHSRNSITLTNLTPGTEYVVSIVALN----GREESPLLIGQQST- 1537
H G P + V +R++ T LT G EYV + A N G +I +S+
Sbjct: 23500 RDAHRPGWLPVSESV--TRSTFKFTRLTEGNEYVFRVAATNRFGIGSYLQSEVIECRSSI 23557
Query: 1538 -VSDVPRDLEVVAATPTSLLISWDAP----AVTVRYYRITYGETGGNSPVQEFTVPGSKS 1592
+ P L++ + + ++W P V Y + E + V+ VP + +
Sbjct: 23558 RIPGPPETLQIFDVSRDGMTLTWYPPEDDGGSQVTGYIVERKEVRADRWVRVNKVPVTMT 23617
Query: 1593 TATISGLKPGVDYTITVYAVTGRGDSPAS--SKPI-SINYRTEIDKPSQMQVTDVQDNSI 1649
+GL G++Y V A+ RG S SKPI +++ KP +VTD S+
Sbjct: 23618 RYRSTGLTEGLEYEHRVTAINARGSGKPSRPSKPIVAMDPIAPPGKPQNPRVTDTTRTSV 23677
Query: 1650 SVKWL----PSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYA 1705
S+ W S VTGY + + TK T E T+ L EY V A
Sbjct: 23678 SLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTKCNTTPTKIREYTLTHLPQGAEYRFRVLA 23737
Query: 1706 QNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDS-IKIAWESPQGQVSRYRVTYSSPEDGI 1764
N G +P + + L + D ++D + QG V R + I
Sbjct: 23738 CNAGGPGEPAEVPGTVKV--TEMLEYPDYELDERYQEGIFVRQGGVIRLTIPIKGKPFPI 23795
Query: 1765 HELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMES------------QPLIGTQSTA 1812
+ +G +D ++ + +T V+ D +S + + +
Sbjct: 23796 CKW--TKEG-QDISKRAMIATSETHTELVIKEADRGDSGTYDLVLENKCGKKAVYIKVRV 23852
Query: 1813 IPAPTD----LKFTQVTPTSLSAQWTPP----NVQLTGYRV--RVTPKEKTGPMKEINLA 1862
I +P L++ + S+ W PP + GY + R PK I+
Sbjct: 23853 IGSPNSPEGPLEYDDIQVRSVRVSWRPPADDGGADILGYILERREVPK---AAWYTIDSR 23909
Query: 1863 PDSSSVVVSGLMVATKYEVSVYALKDTLTSRP--AQGVVTTLENVSPP----RRARVTDA 1916
+S+VV GL +Y V A S+P ++ VT ++PP V D
Sbjct: 23910 VRGTSLVVKGLKENVEYHFRVSAENQFGISKPLKSEEPVTPKTPLNPPEPPSNPPEVLDV 23969
Query: 1917 TETTITISW-RTKTE---TITGFQVDAVPANGQTPIQRT-IKPDVRSYTITGLQPGTDYK 1971
T++++++SW R K + +TG+ ++ + ++ + YT+TGL P +Y+
Sbjct: 23970 TKSSVSLSWSRPKDDGGSRVTGYYIERKETSTDKWVRHNKTQITTTMYTVTGLVPDAEYQ 24029
Query: 1972 IYLYTLND------NARSSPVVI-DASTAIDAPSNLRFLATTPNSLLVSWQPPRA----R 2020
+ ND + S PVV D P L L+ + +S+ + W+ P
Sbjct: 24030 FRIIAQNDVGLSETSPASEPVVCKDPFDKPSQPGELEILSISKDSVTLQWEKPECDGGKE 24089
Query: 2021 ITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEP 2075
I GY ++Y + G + + R + TI GL TEY V A S P
Sbjct: 24090 ILGYWVEYRQSGDSAWKKSNKERIKDKQFTIGGLLEATEYEFRVFAENETGLSRP 24144
Score = 147 bits (371), Expect = 1e-34
Identities = 366/1672 (21%), Positives = 605/1672 (36%), Gaps = 240/1672 (14%)
Query: 612 VEVFITETPSQPNSHPIQ----------WNAPQP---SHISKYILRWRPKNSVGRWKEAT 658
VEV + + P P + I WN P+ S I+ Y++ R +S W + +
Sbjct: 7404 VEVNVLDKPGPPAAFDITDVTNESCLLTWNPPRDDGGSKITNYVVERRATDSEV-WHKLS 7462
Query: 659 IPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPF 718
++ L P Y ++ + YG E PV ++ +T +
Sbjct: 7463 STVKDTNFKATKLIPNKEYIFRVAAENMYGVGE-------------PVQASPITAKYQFD 7509
Query: 719 SPLVATSESVTEITASSFVVSWVSASDT----VSGFRVEYELSEEGDEPQYLDLPSTATS 774
P T ++IT + ++W D ++G+ VE + + +P T+
Sbjct: 7510 PPGPPTRLEPSDITKDAVTLTWCEPDDDGGSPITGYWVERLDPDTDKWVRCNKMPVKDTT 7569
Query: 775 VNIPDLLPGRKYIVNVY--QISEDGEQSL----ILSTSQTTAPDAPPDPTVDQVDDTSIV 828
+ L +KY V ++ G+ S IL P P PTV V TS+
Sbjct: 7570 YRVKGLTNKKKYRFRVLAENLAGPGKPSKSTEPILIKDPIDPPWPPGKPTVKDVGKTSVR 7629
Query: 829 VRWSRPQ----APITGY--RIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYA 882
+ W++P+ A I Y ++ + + E +P T + L L G +Y+ + A
Sbjct: 7630 LNWTKPEHDGGAKIESYVIEMLKTGTDEWVRVAEGVPTTQH--LLPGLMEGQEYSFRVRA 7687
Query: 883 VEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYR 938
V + ES P + PR L+ + +T + WT PE S +T Y
Sbjct: 7688 VNKAGESEPSEPSDPVLCREKLYPPSPPRWLEVINITKNTADLKWTVPEKDGGSPITNYI 7747
Query: 939 VDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSH-GR------ESKPLTA 991
V+ V G + ++T VT L+ G Y F+V A + G+ E L
Sbjct: 7748 VEKRDVRRKGWQTVDTTV-KDTKCTVTPLTEGSLYVFRVAAENAIGQSDYTEIEDSVLAK 7806
Query: 992 QQTTKLDAPTNLQFVNETDSTVLVRWTPPR--AQITGYRLTVGLTRRGQPRQYNVGPSVS 1049
T P L V+ T V ++W PP+ R + R R G +
Sbjct: 7807 DTFTTPGPPYALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKERLGTRWVKAGKTAG 7866
Query: 1050 KYPLRNLQPASEYTVSLVAIKGNQES-----PKATGVFTTLQPGS-SIPPYNTEVTET-- 1101
+ E T ++ E+ + T + + P S PP + VT+
Sbjct: 7867 PDCNFRVTDVIEGTEVQFQVRAENEAGVGHPSEPTEILSIEDPTSPPSPPLDLHVTDAGR 7926
Query: 1102 -TIVITWTP------APRIGFKLGVRPSQGGEAPREVTS----DSGSIVVSGLTPGVEYV 1150
I I W P +P IG+ + + P G E V S D V G+ P EYV
Sbjct: 7927 KHIAIAWKPPEKNGGSPIIGYHVEMCP-VGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYV 7985
Query: 1151 YTIQVLRD-GQERDAPIVNKVVT--PLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYR 1207
++ + G + I VV P PT + LE + ++ + E+ + P +R
Sbjct: 7986 LRVRAVNAIGVSEPSEISENVVAKDPDCKPT-IDLETH---DIIVIEGEKLSIP--VPFR 8039
Query: 1208 ITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEY------NVSVYTV----KDDKESV 1257
PT + +EV +D+ + D++S LE + +YT+ K +
Sbjct: 8040 AVPVPTVSWHKDG-KEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATA 8098
Query: 1258 PISDTIIPEVPQLTDLSFVDITDSSIGLRWTPL---NSSTIIGYRITVVAAGEG--IPIF 1312
I+ +I D+ DIT SS L W P + I+ Y + AG IP+
Sbjct: 8099 SINVKVIGLPGPCKDIKASDITKSSCKLTWEPPEFDGGTPILHYVLERREAGRRTYIPVM 8158
Query: 1313 EDFVDSSVGYYTVTGLEPGIDY--DISVITLINGGESAP---TTLTQQTAVP--PPTDLR 1365
S +TV L P +Y + + + GGE + Q P PP D+
Sbjct: 8159 SGENKLS---WTVKDLIPNGEYFFRVKAVNKVGGGEYIELKNPVIAQDPKQPPDPPVDVE 8215
Query: 1366 FTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLT----NLLP 1421
N + M +TW PP D + ++ Y K + +LT L
Sbjct: 8216 VHNPTAEAMTITW-KPPLYDGGSKIMGYIIEKIAKGEERWKRCNEHLVPILTYTAKGLEE 8274
Query: 1422 GTEYVVSVSSVYEQHESTPLRGRQKT----GLDSP---------------TGIDFSDITA 1462
G EY V + S P R T +D+P +D S +
Sbjct: 8275 GKEYQFRVRAENAAGISEPSRATPPTKAVDPIDAPKVILRTSLEVKRGDEIALDASISGS 8334
Query: 1463 NSFTVHWIAPRATITGYRIRHHPEHFSGRPR------EDRVPHSRNSITLTNLTPGTE-- 1514
T+ WI I I+ R + E V +++ N G
Sbjct: 8335 PYPTITWIKDENVIVPEEIKKRAAPLVRRRKGEVQEEEPFVLPLTQRLSIDNSKKGESQL 8394
Query: 1515 ------------YVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAP 1562
Y++ + +G ++P + T P + TS+L W+ P
Sbjct: 8395 RVRDSLRPDHGLYMIKVENDHGIAKAPCTVSVLDTPGP-PINFVFEDIRKTSVLCKWEPP 8453
Query: 1563 -----AVTVRYYRITYGETGGNSPVQEFTVPGS---KSTATISGLKPGVDYTITVYAVTG 1614
+ + Y T + P E+ V S +++ L G +Y V A
Sbjct: 8454 LDDGGSEIINY---TLEKKDKTKPDSEWIVVTSTLRHCKYSVTKLIEGKEYLFRVRAENR 8510
Query: 1615 RGDS-PASSKP-ISINYRTEIDKPSQMQVTDVQDNSISVKW---LPSSSPVTGYRVTTTP 1669
G P SKP ++ + D P + V DV NS+ VKW + SP+ GY +
Sbjct: 8511 FGPGPPCVSKPLVAKDPFGPPDAPDKPIVEDVTSNSMLVKWNEPKDNGSPILGYWLEKRE 8570
Query: 1670 KNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSG------ESQPLVQTAVTNI 1723
N ++ + + + ++GL + YV V A+N +G S P +
Sbjct: 8571 VNSTHWSRVNKSLLNALKANVDGLLEGLTYVFRVCAENAAGPGKFSPPSDPKTAHDPISP 8630
Query: 1724 DRPKGLAFTDVDVDSIKIAWESPQ----GQVSRYRVTYSSPEDGIHELFPAPDGEEDTAE 1779
P TD +I++ WE P G++ Y V G +E + +
Sbjct: 8631 PGPPIPRVTDTSSTTIELEWEPPAFNGGGEIVGYFV--DKQLVGTNEWSRCTEKMIKVRQ 8688
Query: 1780 --LQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPN 1837
++ +R G++Y + V A++ E P TQ + P + ++ +
Sbjct: 8689 YTVKEIREGADYKLRVSAVNAAGEGPP-GETQPVTVAEPQEPPAVELDVS------VKGG 8741
Query: 1838 VQLTGYRVRVTPKEKTG---PMKEINLAP---DSSSVVVSGLMVATKYEVSVYALKDTLT 1891
+Q+ + P TG P K D VV+ V TK E+ +KD L
Sbjct: 8742 IQIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKDRVVIDN--VGTKSEL---IIKDALR 8796
Query: 1892 SRPAQGVVTTLENVS---PPRRARVTDATETTI------------TISWRTKTE----TI 1932
+ V+T + R V D + ++W + I
Sbjct: 8797 KDHGRYVITATNSCGSKFAAARVEVFDVPGPVLDLKPVVTNRKMCLLNWSDPEDDGGSEI 8856
Query: 1933 TGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDAST 1992
TGF ++ A T ++ I+ + ITGL G +YK + N PV I
Sbjct: 8857 TGFIIERKDAKMHT-WRQPIETERSKCDITGLLEGQEYKFRVIAKNKFGCGPPVEIGPIL 8915
Query: 1993 AID------APSNLRFLATTPNSLLVSWQPPRAR----ITGYIIKYEKPGSPPREVVPRP 2042
A+D +P L + T +++ + W+ PR+ I GYII+ + P E V +
Sbjct: 8916 AVDPLGPPTSPERLTYTERTKSTITLDWKEPRSNGGSPIQGYIIEKRRHDKPDFERVNKR 8975
Query: 2043 RPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRK---KTDELPQLVTL 2091
T + L+ Y V A+ +SEP + + DE+P + L
Sbjct: 8976 LCPTTSFLVENLDEHQMYEFRVKAVNEIGESEPSLPLNVVIQDDEVPPTIKL 9027
Score = 144 bits (362), Expect = 1e-33
Identities = 288/1427 (20%), Positives = 522/1427 (36%), Gaps = 163/1427 (11%)
Query: 696 DFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYE 755
D+T T+ ++ + + P S + ++ + ++SW + Y
Sbjct: 12993 DYTITAENSSGSKSATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYI 13052
Query: 756 LSE-EGDEPQYLDLPSTA--TSVNIPDLLPGRKY-----IVNVYQISEDGEQSLILSTSQ 807
+ + E P + + +T TS ++ L+ G +Y N Y + + ++ +
Sbjct: 13053 VDKRETSRPNWAQVSATVPITSCSVEKLIEGHEYQFRICAENKYGVGDPVFTEPAIAKNP 13112
Query: 808 TTAPDAPPDPTVDQVDDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNL-PETA 862
P P + + + V W P +PITGY + + + T++N P
Sbjct: 13113 YDPPGRCDPPVISNITKDHMTVSWKPPADDGGSPITGYLLEKRETQAVNWTKVNRKPIIE 13172
Query: 863 NSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVK 922
++ + LQ G +Y + A+ + P + P + + T
Sbjct: 13173 RTLKATGLQEGTEYEFRVTAINKAGPGKPSDASKAAYARDPQYPPGPPAFPKVYDTTRSS 13232
Query: 923 VTIMWTPPE----SAVTGYRVDVIPVNLPGEHGQRLPIS-RNTFAEVTGLSPGVTYYFKV 977
V++ W P S + GY V+V + LP + + T EVTGL Y F+V
Sbjct: 13233 VSLSWGKPAYDGGSPIIGYLVEVKRADSDNWVRCNLPQNLQKTRFEVTGLMEDTQYQFRV 13292
Query: 978 FAVSHGRESKP-----------LTAQQTTKLDAPTNLQFVNETDST----VLVRWTPPRA 1022
+AV+ S P + +LDA + T V V+ PP
Sbjct: 13293 YAVNKIGYSDPSDVPDKHYPKDILIPPEGELDADLRKTLILRAGVTMRLYVPVKGRPP-P 13351
Query: 1023 QITGYRLTVGLTRR-GQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGV 1081
+IT + V L R G + + + N A +Y ++L G +E V
Sbjct: 13352 KITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKYILTLENSCGKKEYTIVVKV 13411
Query: 1082 FTTLQPGSSIPPYNTEVTETTIVITWTP------APRIGFKLGVRPSQGGEAPREVTSDS 1135
T PG + E+++ + +TW P +P I + + R ++ T S
Sbjct: 13412 LDT--PGPPVNVTVKEISKDSAYVTWEPPIIDGGSPIINYVVQKRDAERKSWSTVTTECS 13469
Query: 1136 -GSIVVSGLTPGVEYVYTIQVLRD------GQERDAPIVNKVVTPLSPPTNLHLEANPDT 1188
S V+ L G Y + + + G+ RDA V TP P +L + + +
Sbjct: 13470 KTSFRVANLEEGKSYFFRVFAENEYGIGDPGETRDA--VKASQTP-GPVVDLKVRSVSKS 13526
Query: 1189 GVLTVSWERSTTPD---ITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNV 1245
++ W++ + I GY + + N + V+ + + +L+ G EY
Sbjct: 13527 S-CSIGWKKPHSDGGSRIIGYVVDFL----TEENKWQRVMKSLSLQYSAKDLTEGKEYTF 13581
Query: 1246 SVYTVKDDKESVPISDTIIP---------EVPQLTDLSFVDITDSSIGLR---------- 1286
V ++ E P T++ ++ L DL ++ +S+ L+
Sbjct: 13582 RVSAENENGEGTPSEITVVARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPIKGKPAPS 13641
Query: 1287 --WTPLNSSTIIGYRITVVAAGEGIP-IFEDFVDSSVGYYTVTGLEPGIDYDISVITLIN 1343
W R++V ++ I D S G YT+T + ++ +
Sbjct: 13642 VSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKEGTISIKVV 13701
Query: 1344 GGESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAPPP---SIDLTNFLVRYSPVKNEE 1400
G PT ++F + + M + WAPP ++TN+++ N +
Sbjct: 13702 GKPGIPT-----------GPIKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDSVNNK 13750
Query: 1401 DVAELSISPSDNAVVLTNLLPGTEYVVSVSS-----VYEQHESTPLRGRQKTGL-DSPTG 1454
V S + +T L G EY VS+ V E +S P+ R + D+P
Sbjct: 13751 WVTCAS-AVQKTTFRVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVPDAPPP 13809
Query: 1455 IDFSDITANSFTVHWIAPRAT----ITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLT 1510
+ D+ +S ++ W P+ T ITGY + + R ++ P +T LT
Sbjct: 13810 PNIVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTPIRMRDFKVTGLT 13869
Query: 1511 PGTEYVVSIVALN----GREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAV-- 1564
G EY ++A+N G+ P D P EV+ T S+ + W P
Sbjct: 13870 EGLEYEFRVMAINLAGVGKPSLPSEPVVALDPIDPPGKPEVINITRNSVTLIWTEPKYDG 13929
Query: 1565 --TVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASS 1622
+ Y + + S ++ V + T++ L G Y + A G A S
Sbjct: 13930 GHKLTGYIVEKRDLPSKSWMKANHVNVPECAFTVTDLVEGGKYEFRIRAKNTAGAISAPS 13989
Query: 1623 KPI-SINYRTEIDKPSQMQVTDVQD------------NSISV--KWLPSSS-PVTGYRVT 1666
+ +I + E + P+ + ++D N+IS+ K LP SS G +
Sbjct: 13990 ESTETIICKDEYEAPTIVLDPTIKDGLTIKAGDTIVLNAISILGKPLPKSSWSKAGKDIR 14049
Query: 1667 TTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRP 1726
P T+ P + +TI+ ++ A NP G V+ V ++ P
Sbjct: 14050 ------PSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFGTKVEHVKVTVLDVPGP 14103
Query: 1727 KG-LAFTDVDVDSIKIAWESP---QGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQG 1782
G + ++V + + W P G + + + + D +
Sbjct: 14104 PGPVEISNVSAEKATLTWTPPLEDGGSPIKSYILEKRETSRLLWTVVSEDIQSCRHVATK 14163
Query: 1783 LRPGSEYTVSVVALH-----DDMESQPLIGTQSTAIPAPTDL-KFTQVTPTSLSAQWTPP 1836
L G+EY V A++ + ++S+P+ P P + + + VT + + W P
Sbjct: 14164 LIQGNEYIFRVSAVNHYGKGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSWKRP 14223
Query: 1837 ----NVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTS 1892
++TGY V K+ ++ I V+GL + YE V A
Sbjct: 14224 VDDGGSEITGYHVERREKKSLRWVRAIKTPVSDLRCKVTGLQEGSTYEFRVSAENRAGIG 14283
Query: 1893 RPAQGVVTTLEN-----VSPPRRARVTDATETTITISWRTKTE----TITGFQVDAVPAN 1943
P++ + L PP VTD T+ + +++W ITG+ V+
Sbjct: 14284 PPSEASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLAWGKPHYDGGLEITGYVVEHQKVG 14343
Query: 1944 GQTPIQRTIKPDVR--SYTITGLQPGTDYKIYLYTLNDNARSSPVVI 1988
+ I+ T +R + + LQ Y + +ND P VI
Sbjct: 14344 DEAWIKDTTGTALRITQFVVPDLQTKEKYNFRISAINDAGVGEPAVI 14390
Score = 136 bits (342), Expect = 3e-31
Identities = 287/1435 (20%), Positives = 516/1435 (35%), Gaps = 196/1435 (13%)
Query: 794 SEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ----APITGYRIVYSPSV 849
+ G +S + P P ++++ ++ W P + IT Y + +
Sbjct: 13000 NSSGSKSATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYIVDKRETS 13059
Query: 850 EGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPS 909
+ +++ S ++ L G +Y I A + PV + P P
Sbjct: 13060 RPNWAQVSATVPITSCSVEKLIEGHEYQFRICAENKYGVGDPVFTEPAIAKNPYDP--PG 13117
Query: 910 PRDLQFVE-VTDVKVTIMWTPPE----SAVTGYRVDVIPVNLPG-EHGQRLPISRNTFAE 963
D + +T +T+ W PP S +TGY ++ R PI T +
Sbjct: 13118 RCDPPVISNITKDHMTVSWKPPADDGGSPITGYLLEKRETQAVNWTKVNRKPIIERTL-K 13176
Query: 964 VTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKL-------DAPTNLQFVNETDSTVLVR 1016
TGL G Y F+V A++ KP A + P + + T S+V +
Sbjct: 13177 ATGLQEGTEYEFRVTAINKAGPGKPSDASKAAYARDPQYPPGPPAFPKVYDTTRSSVSLS 13236
Query: 1017 WTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSVSK--YPLRNLQPASEYTVSLVAIK 1070
W P + I GY + V + N+ ++ K + + L ++Y + A+
Sbjct: 13237 WGKPAYDGGSPIIGYLVEVKRADSDNWVRCNLPQNLQKTRFEVTGLMEDTQYQFRVYAVN 13296
Query: 1071 GNQESPKATGVFTTLQPGSSIPP---YNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEA 1127
S + IPP + ++ +T I+ R G + + G
Sbjct: 13297 KIGYSDPSDVPDKHYPKDILIPPEGELDADLRKTLIL-------RAGVTMRLYVPVKGRP 13349
Query: 1128 PREVTSDSGSIVVS---GLT------------------PGVEYVYTIQVLRDGQERDAPI 1166
P ++T ++ + GL +Y+ T++ +++ I
Sbjct: 13350 PPKITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKYILTLE--NSCGKKEYTI 13407
Query: 1167 VNKVVTPLSPPTNLHL-EANPDTGVLTVSWERSTTPDITG----YRITTTPTNGQQGNSL 1221
V KV+ PP N+ + E + D+ +T WE P I G + ++ +
Sbjct: 13408 VVKVLDTPGPPVNVTVKEISKDSAYVT--WE---PPIIDGGSPIINYVVQKRDAERKSWS 13462
Query: 1222 EEVVHADQSSCTFDNLSPGLEYNVSVYTVKD--------DKESVPISDTIIPEVPQLTDL 1273
++S NL G Y V+ + +++V S T P V DL
Sbjct: 13463 TVTTECSKTSFRVANLEEGKSYFFRVFAENEYGIGDPGETRDAVKASQTPGPVV----DL 13518
Query: 1274 SFVDITDSSIGLRWTPLNS---STIIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEP 1330
++ SS + W +S S IIGY + + ++ + S Y+ L
Sbjct: 13519 KVRSVSKSSCSIGWKKPHSDGGSRIIGYVVDFLTEENK---WQRVMKSLSLQYSAKDLTE 13575
Query: 1331 GIDYDISVITLINGGESAPTTLT---QQTAVPPPTDLRFTNIGPDT-------------M 1374
G +Y V GE P+ +T + V P DL+ PD +
Sbjct: 13576 GKEYTFRVSAENENGEGTPSEITVVARDDVVAPDLDLKGL---PDLCYLAKENSNFRLKI 13632
Query: 1375 RVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLL-------PGTEYVV 1427
+ P PS+ S K E+ +A + +++ V T L+ +Y +
Sbjct: 13633 PIKGKPAPSV---------SWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTI 13683
Query: 1428 SVSSVYEQHEST-PLRGRQKTGLDSPTG-IDFSDITANSFTVHWIAPR----ATITGYRI 1481
++ +V E T ++ K G+ PTG I F ++TA + T+ W P+ + IT Y I
Sbjct: 13684 TLKNVAGTKEGTISIKVVGKPGI--PTGPIKFDEVTAEAMTLKWAPPKDDGGSEITNY-I 13740
Query: 1482 RHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN------GREESPLLIGQQ 1535
+ + + + + +T L G EY + A N G + P++
Sbjct: 13741 LEKRDSVNNKWVTCASAVQKTTFRVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHP 13800
Query: 1536 STVSDVPRDLEVVAATPTSLLISWDAPAVT----VRYYRITYGETGGNSPVQEFTVPGSK 1591
V D P +V S+ ++W P T + Y + + E + P
Sbjct: 13801 FDVPDAPPPPNIVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTPIRM 13860
Query: 1592 STATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISV 1651
++GL G++Y V A+ G S + ID P + +V ++ NS+++
Sbjct: 13861 RDFKVTGLTEGLEYEFRVMAINLAGVGKPSLPSEPVVALDPIDPPGKPEVINITRNSVTL 13920
Query: 1652 KWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQN 1707
W +TGY V K + T+ L +Y + A+N
Sbjct: 13921 IWTEPKYDGGHKLTGYIVEKRDLPSKSWMKANHVNVPECAFTVTDLVEGGKYEFRIRAKN 13980
Query: 1708 PSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQV----------------S 1751
+G ++ T I + + A T V +IK G S
Sbjct: 13981 TAGAISAPSESTETIICKDEYEAPTIVLDPTIKDGLTIKAGDTIVLNAISILGKPLPKSS 14040
Query: 1752 RYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQST 1811
+ I ++ P T + + EYT++ +
Sbjct: 14041 WSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFGTKVEHVKVTVLDV 14100
Query: 1812 AIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVR--VTPKEKTGPMKEINLAPDSSSV- 1868
P P ++ + V+ + WTPP ++ G ++ + K +T + ++ D S
Sbjct: 14101 PGP-PGPVEISNVSAEKATLTWTPP-LEDGGSPIKSYILEKRETSRLLWTVVSEDIQSCR 14158
Query: 1869 -VVSGLMVATKYEVSVYALKDTLTSRPAQG----VVTTLENVSPPRRARVTDATETTITI 1923
V + L+ +Y V A+ P Q +V PP + V++ T+ T T+
Sbjct: 14159 HVATKLIQGNEYIFRVSAVNHYGKGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTATV 14218
Query: 1924 SWRTKTE----TITGFQVDAVPANGQTPIQRTIKPDVRSY--TITGLQPGTDYKIYLYTL 1977
SW+ + ITG+ V+ + R IK V +TGLQ G+ Y+ +
Sbjct: 14219 SWKRPVDDGGSEITGYHVERREKKSLRWV-RAIKTPVSDLRCKVTGLQEGSTYEFRVSAE 14277
Query: 1978 N-------DNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYII 2026
N A S ++ DA+ PSN TT S ++W P ITGY++
Sbjct: 14278 NRAGIGPPSEASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLAWGKPHYDGGLEITGYVV 14337
Query: 2027 KYEKPGSPPREVVPRPRPG----VTEATITGLEPGTEYTIYVIALKNNQKSEPLI 2077
+++K G E + G +T+ + L+ +Y + A+ + EP +
Sbjct: 14338 EHQKVGD---EAWIKDTTGTALRITQFVVPDLQTKEKYNFRISAINDAGVGEPAV 14389
Score = 134 bits (338), Expect = 9e-31
Identities = 378/1880 (20%), Positives = 675/1880 (35%), Gaps = 278/1880 (14%)
Query: 628 IQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISI 684
+ W P S I+ Y+L R +V K P + GL+ G YE ++ +I
Sbjct: 13134 VSWKPPADDGGSPITGYLLEKRETQAVNWTKVNRKPIIERTLKATGLQEGTEYEFRVTAI 13193
Query: 685 QQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSW---- 740
+ G + + S + P V + T SS +SW
Sbjct: 13194 NKAGPGKPSD------------ASKAAYARDPQYPPGPPAFPKVYDTTRSSVSLSWGKPA 13241
Query: 741 VSASDTVSGFRVEYELSEEGDEPQYLDLPST--ATSVNIPDLLPGRKYIVNVYQISEDGE 798
+ G+ VE + + + D +LP T + L+ +Y VY +++ G
Sbjct: 13242 YDGGSPIIGYLVEVKRA-DSDNWVRCNLPQNLQKTRFEVTGLMEDTQYQFRVYAVNKIG- 13299
Query: 799 QSLILSTSQTTAPD--------APPDPTVDQVDDTSIVVR---WSRPQAPITGYRIVYSP 847
+ + PD PP+ +D ++++R R P+ G P
Sbjct: 13300 -----YSDPSDVPDKHYPKDILIPPEGELDADLRKTLILRAGVTMRLYVPVKGRP---PP 13351
Query: 848 SVEGSSTELNLPETAN-SVTLSDLQPGV-----------QYNITIYAVEENQESTPVVIQ 895
+ S +NL + + +D + +Y +T+ +E T VV
Sbjct: 13352 KITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKYILTLENSCGKKEYTIVVKV 13411
Query: 896 QETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPGEHG 951
+T G P + TV E++ + W PP S + Y V
Sbjct: 13412 LDTPGPPVNVTVK--------EISKDSAYVTWEPPIIDGGSPIINYVVQKRDAERKSWST 13463
Query: 952 QRLPISRNTFAEVTGLSPGVTYYFKVFAVSH---GRESKPLTAQQTTKLDAP-TNLQFVN 1007
S+ +F V L G +Y+F+VFA + G + A + ++ P +L+ +
Sbjct: 13464 VTTECSKTSF-RVANLEEGKSYFFRVFAENEYGIGDPGETRDAVKASQTPGPVVDLKVRS 13522
Query: 1008 ETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYT 1063
+ S+ + W P ++I GY + LT + ++ S+ +Y ++L EYT
Sbjct: 13523 VSKSSCSIGWKKPHSDGGSRIIGYVVDF-LTEENKWQRVMKSLSL-QYSAKDLTEGKEYT 13580
Query: 1064 VSLVAIKGNQE-SPKATGVFT---TLQPG---SSIPPYNTEVTETT-----IVITWTPAP 1111
+ A N E +P V + P +P E + I I PAP
Sbjct: 13581 FRVSAENENGEGTPSEITVVARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPIKGKPAP 13640
Query: 1112 RIGFKLGVRP-SQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKV 1170
+ +K G P + E ++ + +++V YTI + ++ I KV
Sbjct: 13641 SVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKEGTISIKV 13700
Query: 1171 VTPLSPPTNLHLEANPDTGVLTVSW---ERSTTPDITGYRITTTPTNGQQGNSLEEVVHA 1227
V PT +T+ W + +IT Y + + + + V
Sbjct: 13701 VGKPGIPTGPIKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDSVNNKWVTCASAV-- 13758
Query: 1228 DQSSCTFDNLSPGLEYNVSV-----YTVKDDKESVPI---SDTIIPEVPQLTDLSFVDIT 1279
+++ L G+EY V Y V + +S PI +P+ P ++ VD+
Sbjct: 13759 QKTTFRVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVPDAPPPPNI--VDVR 13816
Query: 1280 DSSIGLRWT---PLNSSTIIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDI 1336
S+ L WT S I GY + + + + + VTGL G++Y+
Sbjct: 13817 HDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTPIRMRDFKVTGLTEGLEYEF 13876
Query: 1337 SVITLINGGESAPTTLTQQTA----VPPPTDLRFTNIGPDTMRVTWAPPP---SIDLTNF 1389
V+ + G P+ ++ + PP NI +++ + W P LT +
Sbjct: 13877 RVMAINLAGVGKPSLPSEPVVALDPIDPPGKPEVINITRNSVTLIWTEPKYDGGHKLTGY 13936
Query: 1390 LVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEY---------VVSVSSVYEQHESTP 1440
+V + ++ + ++ + A +T+L+ G +Y ++S+ E E+
Sbjct: 13937 IVEKRDLPSKSWMKANHVNVPECAFTVTDLVEGGKYEFRIRAKNTAGAISAPSESTETII 13996
Query: 1441 LRGRQK--TGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVP 1498
+ + T + PT D I A V +I G + P+ + +D P
Sbjct: 13997 CKDEYEAPTIVLDPTIKDGLTIKAGDTIV---LNAISILGKPL---PKSSWSKAGKDIRP 14050
Query: 1499 HSRNSITLTNLT-----------PGTEYVVSIVALNGREESPLLIGQQSTVSDV---PRD 1544
IT T + EY ++ G + + + TV DV P
Sbjct: 14051 SDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFGTKVEHVKV----TVLDVPGPPGP 14106
Query: 1545 LEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATI-------- 1596
+E+ + ++W P E GG SP++ + + +++ +
Sbjct: 14107 VEISNVSAEKATLTWTPPL-----------EDGG-SPIKSYILEKRETSRLLWTVVSEDI 14154
Query: 1597 -------SGLKPGVDYTITVYAVT--GRGDSPASSKPISINYR-TEIDKPSQMQVTDVQD 1646
+ L G +Y V AV G+G+ P S+P+ + R P + +V++V
Sbjct: 14155 QSCRHVATKLIQGNEYIFRVSAVNHYGKGE-PVQSEPVKMVDRFGPPGPPEKPEVSNVTK 14213
Query: 1647 NSISVKWL----PSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVS 1702
N+ +V W S +TGY V K + + GLQ Y
Sbjct: 14214 NTATVSWKRPVDDGGSEITGYHVERREKKSLRWVRAIKTPVSDLRCKVTGLQEGSTYEFR 14273
Query: 1703 VYAQNPSGESQP-------LVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQG----QVS 1751
V A+N +G P L++ A P TD S +AW P +++
Sbjct: 14274 VSAENRAGIGPPSEASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLAWGKPHYDGGLEIT 14333
Query: 1752 RYRVTYSSPEDGIHELFPAPDGEEDTA-ELQGLRPGSEYTVSVVALHDDMESQPLIGTQS 1810
Y V + D T + L+ +Y + A++D +P +
Sbjct: 14334 GYVVEHQKVGDEAWIKDTTGTALRITQFVVPDLQTKEKYNFRISAINDAGVGEPAV---- 14389
Query: 1811 TAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPD------ 1864
IP ++ L A+ V G +R+ K P E+ D
Sbjct: 14390 --IPDVEIVEREMAPDFELDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKN 14447
Query: 1865 ------SSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVT--TLENVSPPRRARVTDA 1916
+ S + + +Y+ + + + G V L+ P R TD
Sbjct: 14448 RANIENTESFTLLIIPECNRYDTGKFVMTIENPAGKKSGFVNVRVLDTPGPVLNLRPTDI 14507
Query: 1917 TETTITISWRTKT----ETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKI 1972
T+ ++T+ W IT + V+ A ++ T K +Y +TGL G +Y
Sbjct: 14508 TKDSVTLHWDLPLIDGGSRITNYIVEKREATRKSYSTATTKCHKCTYKVTGLSEGCEYFF 14567
Query: 1973 YLYTLNDNARSSPV----VIDASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGY 2024
+ N+ P + AS A P +L + T +++ ++W P+ ++ITGY
Sbjct: 14568 RVMAENEYGIGEPTETTEPVKASEAPSPPDSLNIMDITKSTVSLAWPKPKHDGGSKITGY 14627
Query: 2025 IIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDE 2084
+I+ ++ GS + + E + L G EYT V+A+ + +S P R
Sbjct: 14628 VIEAQRKGSDQWTHITTVKG--LECVVRNLTEGEEYTFQVMAVNSAGRSAPRESRPVI-- 14683
Query: 2085 LPQLVTLPHPNLHGPEILDVPSTVQKTPFVTHPGYDTGNGIQLPGTSGQQPSV----GQQ 2140
+ + LP +L G + + + G + +++P +P+V G Q
Sbjct: 14684 VKEQTMLPELDLRG---------IYQKLVIAKAGDNI--KVEIPVLGRPKPTVTWKKGDQ 14732
Query: 2141 MIFEEHGFRRTTPPTTATP--------IRHRPRPYPPN----VGEEIQIGHIPREDVDYH 2188
++ + +R TTAT +R PYP VGE + I D+
Sbjct: 14733 ILKQT---QRVNFETTATSTILNINECVRSDSGPYPLTARNIVGEVGDVITIQVHDIP-- 14787
Query: 2189 LYPHGPGLNPNASTGQEALSQTTISWAPFQDTSEYIISCHPV---GTDEEP-LQFRVPGT 2244
GP P + + T SW P ++ IS + V TD ++
Sbjct: 14788 ----GPPTGP-IKFDEVSSDFVTFSWDPPENDGGVPISNYVVEMRQTDSTTWVELATTVI 14842
Query: 2245 STSATLTGLTRGATYNIIVEALKDQQRHKVREEVVTVGNSVNEGLNQPTDDSCFDPYTVS 2304
T+ T LT G Y V+A Q R+ V + + N P V+
Sbjct: 14843 RTTYKATRLTTGLEYQFRVKA---QNRYGVGPGITSACIVANYPFKVPGPPGTPQVTAVT 14899
Query: 2305 HYAVGDEW-ERMSESGFKLL 2323
++ W E +S+ G +L
Sbjct: 14900 KDSMTISWHEPLSDGGSPIL 14919
Score = 128 bits (322), Expect = 6e-29
Identities = 343/1604 (21%), Positives = 574/1604 (35%), Gaps = 260/1604 (16%)
Query: 611 PVEVFITETPSQPNSHPIQWNAPQ---PSHISKYILRWRPKNSVGRWKEATIPGHLNS-- 665
P ++ I + S +S + W+ P S ++ Y++ R + W + G + +
Sbjct: 20798 PAKIRIAD--STKSSITLGWSKPVYDGGSAVTGYVVEIR-QGEEEEWTTVSTKGEVRTTE 20854
Query: 666 YTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATS 725
Y + LKPGV Y ++ ++ G E + + S +
Sbjct: 20855 YVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQAKDILEAPEIDLDVALRTSVIAKAG 20914
Query: 726 ESVTEITASSF----VVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLL 781
E V + V+W + G Y + E D L +P +
Sbjct: 20915 EDVQVLIPFKGRPPPTVTWRKDEKNL-GSDARYSI-ENTDSSSLLTIPQVTRNDT----- 20967
Query: 782 PGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ----AP 837
KYI+ + + + S + S P A V V ++ + W P +P
Sbjct: 20968 --GKYILTIENGVGEPKSSTV-SVKVLDTPAACQKLQVKHVSRGTVTLLWDPPLIDGGSP 21024
Query: 838 ITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQE 897
I Y I + + + + ++ ++ S L DL + + A E P E
Sbjct: 21025 IINYVIEKRDATKRTWSVVSHKCSSTSFKLIDLSEKTPFFFRVLAENEIGIGEPC----E 21080
Query: 898 TTGTPRSDTVPSP-RDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPVNLPGEHG- 951
TT ++ VP+P RDL + T V + WT P+ S +T Y V+ GE
Sbjct: 21081 TTEPVKAAEVPAPIRDLSMKDSTKTSVILSWTKPDFDGGSVITEY---VVERKGKGEQTW 21137
Query: 952 QRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDS 1011
IS+ EV+ L F+VFA + S P+T T + L E D
Sbjct: 21138 SHAGISKTCEIEVSQLKEQSVLEFRVFAKNEKGLSDPVTIGPITVKE----LIITPEVDL 21193
Query: 1012 TVLVRWTPPRAQIT---GYRLTVGLTRRGQPRQYNVGPSVS----KYPLRNLQ------P 1058
+ + P AQ+T G+ + + L +G+P+ PS+S PL+ +
Sbjct: 21194 SDI-----PGAQVTVRIGHNVHLELPYKGKPK-----PSISWLKDGLPLKESEFVRFSKT 21243
Query: 1059 ASEYTVSLVAIKGNQESPKATGVFT-------------TLQPGSSI--PPYNTEVTETTI 1103
++ T+S+ K + K T + TL P S P E+ ++
Sbjct: 21244 ENKITLSIKNAK-KEHGGKYTVILDNAVCRIAVPITVITLGPPSKPKGPIRFDEIKADSV 21302
Query: 1104 VITWTPAPRIGFKLGVRPSQGGEAP------REVTSDSGSIVVSG----------LTPGV 1147
+++W G GGE RE + + +V S L
Sbjct: 21303 ILSWDVPEDNG---------GGEITCYSIEKRETSQTNWKMVCSSVARTTFKVPNLVKDA 21353
Query: 1148 EYVYTIQVLRDGQERDAPIVNKVVTP-----LSPPTNLHLEANPDTGVLTVSWERSTTP- 1201
EY + ++ + P+V+ ++ + P + N + ++++W+
Sbjct: 21354 EYQFRVRA-ENRYGVSQPLVSSIIVAKHQFRIPGPPGKPVIYNVTSDGMSLTWDAPVYDG 21412
Query: 1202 --DITGYRITTTPTNG---QQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKES 1256
++TG+ + N Q+ N+ + + T L GL+Y VY S
Sbjct: 21413 GSEVTGFHVEKKERNSILWQKVNT--SPISGREYRAT--GLVEGLDYQFRVYAENSAGLS 21468
Query: 1257 VPISDT-----IIPEVPQLTDLSFVDITDSSIGLRWTPL---NSSTIIGYRITVVAAGEG 1308
P + + P P T ++D+T +I L+W P S I+GY I E
Sbjct: 21469 SPSDPSKFTLAVSPVDPPGTP-DYIDVTRETITLKWNPPLRDGGSKIVGYSIEKRQGNER 21527
Query: 1309 IPIFEDFVDSSVGYYTVTGLEPGIDYDISVI------TLINGGESAPTTLTQQTAVPPPT 1362
+ +F D S YTVTGL PG Y+ +I T+ +S+ +T+ VPP
Sbjct: 21528 W-VRCNFTDVSECQYTVTGLSPGDRYEFRIIARNAVGTISPPSQSSGIIMTRDENVPP-- 21584
Query: 1363 DLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNE---EDVAELSISPSDNAVVLTNL 1419
GP+ LV+ PV +D E+ + + +T++
Sbjct: 21585 ---IVEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMN---MEITDV 21638
Query: 1420 LPGTEYVV--------SVSSVYEQHESTPLRGRQKTGLDSPTG-----IDFSDITANSFT 1466
L T V V +V ++ S + K + G I F++IT T
Sbjct: 21639 LGSTSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQDTPGKVVGPIRFTNITGEKMT 21698
Query: 1467 VHWIAPR----ATITGYRI-RHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVA 1521
+ W AP A IT Y I + + ED+ S T L G EY + A
Sbjct: 21699 LWWDAPLNDGCAPITHYIIEKRETSRLAWALIEDKC--EAQSYTAIKLINGNEYQFRVSA 21756
Query: 1522 LN----GR--EESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGE 1575
+N GR + P++ Q TV D P E T S+ ++W P E
Sbjct: 21757 VNKFGVGRPLDSDPVVAQIQYTVPDAPGIPEPSNITGNSITLTWARP------------E 21804
Query: 1576 TGGNSPVQEFTV-----------------PGSKSTATISGLKPGVDYTITVYAVTGRGDS 1618
+ G S +Q++ + P S++ ++GL G +Y V A G
Sbjct: 21805 SDGGSEIQQYILERREKKSTRWVKVISKRPISETRFKVTGLTEGNEYEFHVMAENAAGVG 21864
Query: 1619 PASSKPISINYRTEIDKPSQ---MQVTDVQDNSISVKW----LPSSSPVTGYRVTTTPKN 1671
PAS I R ++ P ++VTD ++S++W + GY + +
Sbjct: 21865 PASGISRLIKCREPVNPPGPPTVVKVTDTSKTTVSLEWSKPVFDGGMEIIGYIIEMCKAD 21924
Query: 1672 GPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTA-VTNIDRPKGLA 1730
K +T T+ LQ EY V A N +G+ T + +DR L
Sbjct: 21925 LGDWHKVNAEACVKTRYTVTDLQAGEEYKFRVSAINGAGKGDSCEVTGTIKAVDR---LT 21981
Query: 1731 FTDVDVDS-IKIAWESPQGQVSRYRVTY----------SSPEDGIH---ELFPAPDGEED 1776
++D+D+ K G R + Y S P+ + ++
Sbjct: 21982 APELDIDANFKQTHVVRAGASIRLFIAYQGRPTPTAVWSKPDSNLSLRADIHTTDSFSTL 22041
Query: 1777 TAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPP 1836
T E +YT++V + T P P + F VT S + W P
Sbjct: 22042 TVENCNRNDAGKYTLTVENNSGSKSITFTVKVLDTPGP-PGPITFKDVTRGSATLMWDAP 22100
Query: 1837 NVQLTGYRVRVTPKEKTGPMKE----INLAPDSSSVVVSGLMVATKYEVSVYALKDTLTS 1892
+ G R+ EK + I+ V+ L Y V A+ +
Sbjct: 22101 LLD-GGARIHHYVVEKREASRRSWQVISEKCTRQIFKVNDLAEGVPYYFRVSAVNEYGVG 22159
Query: 1893 RPAQ--GVVTTLENVSPPRRARVTDATETTITISW----RTKTETITGFQVDAVPANGQT 1946
P + + E +PPRR V D ++++ ++W ITG+ ++
Sbjct: 22160 EPYEMPEPIVATEQPAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSDF 22219
Query: 1947 PIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATT 2006
++ + ++T+ L T+Y+ + ND S P +S I P
Sbjct: 22220 WVEAGHTKQL-TFTVERLVEKTEYEFRVKAKNDAGYSEPREAFSSVIIKEPQ------IE 22272
Query: 2007 PNSLLVSWQPPRARITGYIIKYEKPGSPPREVVP---RPRPGVT 2047
P + L IT +I K GSP VP RP P VT
Sbjct: 22273 PTADLTG-------ITNQLITC-KAGSPFTIDVPISGRPAPKVT 22308
Score = 124 bits (311), Expect = 1e-27
Identities = 291/1338 (21%), Positives = 513/1338 (38%), Gaps = 174/1338 (13%)
Query: 780 LLPGRKYI-----VNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRP 834
++ G +YI VN Y I E E +++ + P P P V ++ S+ V WSRP
Sbjct: 20658 IIKGNEYIFRVRAVNKYGIGEPLESDSVVAKNAFVTPGPPGIPEVTKITKNSMTVVWSRP 20717
Query: 835 QA----PITGYRIVYSPSVEGSSTEL---NLPETANSVTLSDLQPGVQYNI-TIYAVEEN 886
A I+GY + ++ + +T VT QY + + A +
Sbjct: 20718 IADGGSDISGYFLEKRDKKSLGWFKVLKETIRDTRQKVTGLTENSDYQYRVCAVNAAGQG 20777
Query: 887 QESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVI 942
S P + D P ++ + T +T+ W+ P SAVTGY V++
Sbjct: 20778 PFSEP---SEFYKAADPIDPPGPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVVEI- 20833
Query: 943 PVNLPGEHGQRLPIS-----RNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTK- 996
GE + +S R T V+ L PGV YYF+V AV+ + +P+ + +
Sbjct: 20834 ---RQGEEEEWTTVSTKGEVRTTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQA 20890
Query: 997 ---LDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQP--------RQYNVG 1045
L+AP E D V +R T A+ G + V + +G+P + N+G
Sbjct: 20891 KDILEAP-------EIDLDVALR-TSVIAK-AGEDVQVLIPFKGRPPPTVTWRKDEKNLG 20941
Query: 1046 PSVSKYPLRNLQPASEYTVS----------LVAIKGNQESPKATGVFTTL--QPGSSIPP 1093
S ++Y + N +S T+ ++ I+ PK++ V + P +
Sbjct: 20942 -SDARYSIENTDSSSLLTIPQVTRNDTGKYILTIENGVGEPKSSTVSVKVLDTPAACQKL 21000
Query: 1094 YNTEVTETTIVITWTP------APRIGFKLGVRPS---QGGEAPREVTSDSGSIV-VSGL 1143
V+ T+ + W P +P I + + R + + +S S ++ +S
Sbjct: 21001 QVKHVSRGTVTLLWDPPLIDGGSPIINYVIEKRDATKRTWSVVSHKCSSTSFKLIDLSEK 21060
Query: 1144 TPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDI 1203
TP V + G+ + K +P +L ++ + T V+ +SW T PD
Sbjct: 21061 TPFFFRVLAENEIGIGEPCETTEPVKAAEVPAPIRDLSMKDSTKTSVI-LSW---TKPDF 21116
Query: 1204 TGYRITTTPTNGQQGNSLEEVVHADQS-SCTFD----NLSPGLEYNVSVYTVKDDKESVP 1258
G + T ++G + HA S +C + LE+ V K + V
Sbjct: 21117 DGGSVITEYVVERKGKGEQTWSHAGISKTCEIEVSQLKEQSVLEFRVFAKNEKGLSDPVT 21176
Query: 1259 ISDTIIPEVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGY----RITVVAAGEGIPIFE- 1313
I + E+ ++ DI + + +R N + Y + ++ +G+P+ E
Sbjct: 21177 IGPITVKELIITPEVDLSDIPGAQVTVR-IGHNVHLELPYKGKPKPSISWLKDGLPLKES 21235
Query: 1314 DFVDSSVGYYTVT------GLEPGIDYDISVITLINGGESAPTTLTQQTAVPPPTDLRFT 1367
+FV S +T E G Y + + + T +T P +RF
Sbjct: 21236 EFVRFSKTENKITLSIKNAKKEHGGKYTVILDNAVCRIAVPITVITLGPPSKPKGPIRFD 21295
Query: 1368 NIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSI---SPSDNAVVLTNLLPGTE 1424
I D++ ++W P + + YS K E + S + + NL+ E
Sbjct: 21296 EIKADSVILSWDVPED-NGGGEITCYSIEKRETSQTNWKMVCSSVARTTFKVPNLVKDAE 21354
Query: 1425 YVVSVSSVYEQHESTPL-----RGRQKTGLDSPTGID-FSDITANSFTVHWIAP----RA 1474
Y V + S PL + + + P G ++T++ ++ W AP +
Sbjct: 21355 YQFRVRAENRYGVSQPLVSSIIVAKHQFRIPGPPGKPVIYNVTSDGMSLTWDAPVYDGGS 21414
Query: 1475 TITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQ 1534
+TG+ + + + + P S T L G +Y + A N S
Sbjct: 21415 EVTGFHVEKKERNSILWQKVNTSPISGREYRATGLVEGLDYQFRVYAENSAGLSSPSDPS 21474
Query: 1535 QSTVS----DVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYG---ETGGNSPVQEFTV 1587
+ T++ D P + + T ++ + W+ P + Y G V+
Sbjct: 21475 KFTLAVSPVDPPGTPDYIDVTRETITLKWNPPLRDGGSKIVGYSIEKRQGNERWVRCNFT 21534
Query: 1588 PGSKSTATISGLKPGVDYTITVYAVTGRGD-SPASSKPISINYRTEIDKPSQMQVTDVQD 1646
S+ T++GL PG Y + A G SP S I R E P + D
Sbjct: 21535 DVSECQYTVTGLSPGDRYEFRIIARNAVGTISPPSQSSGIIMTRDENVPPIVEFGPEYFD 21594
Query: 1647 -------NSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTK----TAGPDQTEMTIEGLQP 1695
S+ +K L PV RVT K+G K T T + +
Sbjct: 21595 GLIIKSGESLRIKALVQGRPVP--RVTWF-KDGVEIEKRMNMEITDVLGSTSLFVRDATR 21651
Query: 1696 TVEYVVSVYAQNPSGESQPLVQTAVTNIDRP----KGLAFTDVDVDSIKIAWESPQGQ-- 1749
V +V A+N SG ++ ++ V D P + FT++ + + + W++P
Sbjct: 21652 DHRGVYTVEAKNASGSAKAEIKVKVQ--DTPGKVVGPIRFTNITGEKMTLWWDAPLNDGC 21709
Query: 1750 --VSRYRVTYSSPEDGIHELFPAPDGEEDTAELQG-----LRPGSEYTVSVVALHD---- 1798
++ Y + L ED E Q L G+EY V A++
Sbjct: 21710 APITHYIIEKRETSRLAWALI------EDKCEAQSYTAIKLINGNEYQFRVSAVNKFGVG 21763
Query: 1799 -DMESQPLIGTQSTAIP-APTDLKFTQVTPTSLSAQWTPP----NVQLTGYRVRVTPKEK 1852
++S P++ +P AP + + +T S++ W P ++ Y + K+
Sbjct: 21764 RPLDSDPVVAQIQYTVPDAPGIPEPSNITGNSITLTWARPESDGGSEIQQYILERREKKS 21823
Query: 1853 TGPMKEINLAPDSSS-VVVSGLMVATKYEVSVYALKDTLTSRPAQGV---VTTLENVS-- 1906
T +K I+ P S + V+GL +YE V A ++ PA G+ + E V+
Sbjct: 21824 TRWVKVISKRPISETRFKVTGLTEGNEYEFHVMA-ENAAGVGPASGISRLIKCREPVNPP 21882
Query: 1907 -PPRRARVTDATETTITISWRTKT----ETITGFQVDAVPANGQTPIQRTIKPDVRS-YT 1960
PP +VTD ++TT+++ W I G+ ++ A+ + + V++ YT
Sbjct: 21883 GPPTVVKVTDTSKTTVSLEWSKPVFDGGMEIIGYIIEMCKADLGDWHKVNAEACVKTRYT 21942
Query: 1961 ITGLQPGTDYKIYLYTLN 1978
+T LQ G +YK + +N
Sbjct: 21943 VTDLQAGEEYKFRVSAIN 21960
Score = 124 bits (310), Expect = 2e-27
Identities = 338/1629 (20%), Positives = 573/1629 (35%), Gaps = 196/1629 (12%)
Query: 624 NSHPIQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNS--YTIKGLKPGVVYE 678
NS + W P+ S I +YIL R K S RW + ++ + + GL G YE
Sbjct: 21794 NSITLTWARPESDGGSEIQQYILERREKKST-RWVKVISKRPISETRFKVTGLTEGNEYE 21852
Query: 679 GQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVV 738
+++ G + PV P P V VT+ + ++ +
Sbjct: 21853 FHVMAENAAGVGPASGIS-RLIKCREPVNP--------PGPPTVV---KVTDTSKTTVSL 21900
Query: 739 SW----VSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQIS 794
W + G+ +E ++ GD + T + DL G +Y V I+
Sbjct: 21901 EWSKPVFDGGMEIIGYIIEMCKADLGDWHKVNAEACVKTRYTVTDLQAGEEYKFRVSAIN 21960
Query: 795 EDGEQSLILSTSQTTAPD--APPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGS 852
G+ T A D P+ +D + VVR Y+ +P+ S
Sbjct: 21961 GAGKGDSCEVTGTIKAVDRLTAPELDIDANFKQTHVVRAGASIRLFIAYQGRPTPTAVWS 22020
Query: 853 STELNLPETANSVTLSDLQPGVQYNIT-------IYAVEENQESTPVVIQQETTGTPRSD 905
+ NL A+ T N VE N S + + TP
Sbjct: 22021 KPDSNLSLRADIHTTDSFSTLTVENCNRNDAGKYTLTVENNSGSKSITFTVKVLDTPGP- 22079
Query: 906 TVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPGEHGQRLPISRNTF 961
P + F +VT T+MW P + + Y V+ + +R F
Sbjct: 22080 ----PGPITFKDVTRGSATLMWDAPLLDGGARIHHYVVEKREASRRSWQVISEKCTRQIF 22135
Query: 962 AEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQ----TTKLDAPTNLQFVNETDSTVLVRW 1017
+V L+ GV YYF+V AV+ +P + T + P L V+ + S+ ++ W
Sbjct: 22136 -KVNDLAEGVPYYFRVSAVNEYGVGEPYEMPEPIVATEQPAPPRRLDVVDTSKSSAVLAW 22194
Query: 1018 TPP----RAQITGYRLTVGLTRRGQPRQYNVGPSVS-KYPLRNLQPASEY---------- 1062
P ++ITGY L + ++G G + + + L +EY
Sbjct: 22195 LKPDHDGGSRITGYLLE--MRQKGSDFWVEAGHTKQLTFTVERLVEKTEYEFRVKAKNDA 22252
Query: 1063 -------TVSLVAIKGNQESPKA--TGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRI 1113
S V IK Q P A TG+ L + P+ +V I+ PAP++
Sbjct: 22253 GYSEPREAFSSVIIKEPQIEPTADLTGITNQLITCKAGSPFTIDVP-----ISGRPAPKV 22307
Query: 1114 GFKL-GVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVT 1172
+KL +R + T D ++ V G Y + + + + V+
Sbjct: 22308 TWKLEEMRLKETDRVSITTTKDRTTLTVKDSMRGDSGRYFLTLENTAGVKTFSVTVVVIG 22367
Query: 1173 PLSPPTNLHLEANPDTGVLTVSW---ERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQ 1229
P T ++ +SW + +IT Y + + + V Q
Sbjct: 22368 RPGPVTGPIEVSSVSAESCVLSWGEPKDGGGTEITNYIVEKRESGTTAWQLVNSSVKRTQ 22427
Query: 1230 SSCTFDNLSPGLEYNVSV-----YTVKDDKESVPI---SDTIIPEVPQLTDLSFVDITDS 1281
T +L+ +EY+ V + V ES PI + P P T ++ +
Sbjct: 22428 IKVT--HLTKYMEYSFRVSSENRFGVSKPLESAPIIAEHPFVPPSAP--TRPEVYHVSAN 22483
Query: 1282 SIGLRWTPL---NSSTIIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISV 1338
++ +RW S IIGY + + + E+ V Y VTGL G++Y
Sbjct: 22484 AMSIRWEEPYHDGGSKIIGYWVEKKERNTILWVKENKVPCLECNYKVTGLVEGLEYQFRT 22543
Query: 1339 ITLINGGES----APTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAPPP---SIDLTNFLV 1391
L G S A + Q V P T++ T+ + W+ P + +++
Sbjct: 22544 YALNAAGVSKASEASRPIMAQNPVDAPGRPEVTDVTRSTVSLIWSAPAYDGGSKVVGYII 22603
Query: 1392 RYSPVKNEEDVAELSIS---PSDNAVVLTNLLPGTEYVVSVSS------VYEQHEST-PL 1441
PV D L + SDN +T L G Y V + + + EST P+
Sbjct: 22604 ERKPVSEVGDGRWLKCNYTIVSDNFFTVTALSEGDTYEFRVLAKNAAGVISKGSESTGPV 22663
Query: 1442 RGRQ-----KTGLDSPTGIDFSDITANSFTVHWIA----PRATITGYRIRHHPEHFSGRP 1492
R K LD+ D I A S V A P I + +
Sbjct: 22664 TCRDEYAPPKAELDARLHGDLVTIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVS 22723
Query: 1493 REDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVP---RDLEVVA 1549
+ + I + + +Y +++ +G + +++ V D P L V
Sbjct: 22724 LQYTGKRATAVIKFCDRSDSGKYTLTVKNASGTKAVSVMV----KVLDSPGPCGKLTVSR 22779
Query: 1550 ATPTSLLISWDAP----AVTVRYYRITYGETGGNSPVQEFTVPGSKSTAT--ISGLKPGV 1603
T ++W P + +Y + ET S + V G T + ++ L
Sbjct: 22780 VTQEKCTLAWSLPQEDGGAEITHYIVERRET---SRLNWVIVEGECPTLSYVVTRLIKNN 22836
Query: 1604 DYTITVYAVTGRGDS-PASSKPI-SINYRTEIDKPSQMQVTDVQDNSISVKWLPSSS--- 1658
+Y V AV G P S+PI + N T P + I ++W S
Sbjct: 22837 EYIFRVRAVNKYGPGVPVESEPIVARNSFTIPSPPGIPEEVGTGKEHIIIQWTKPESDGG 22896
Query: 1659 -PVTGYRVTTTPKNGPGPTK-TKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLV 1716
++ Y V K T+ K T + + L +Y V A N +G S+P
Sbjct: 22897 NEISNYLVDKREKKSLRWTRVNKDYVVYDTRLKVTSLMEGCDYQFRVTAVNAAGNSEPSE 22956
Query: 1717 QTAVTNIDR-------PKGLAFTDVDVDSIKIAWESPQGQVSRYRVTY-----SSPEDGI 1764
+ + P D SI +AW P V Y D
Sbjct: 22957 ASNFISCREPSYTPGPPSAPRVVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDTDQW 23016
Query: 1765 HELFPAPDGEEDTAELQGLRPGSEYTVSVVALH---------DDMESQPLIGTQSTAIPA 1815
+ + + L+ G +Y+ V A++ E +P+ + +
Sbjct: 23017 YRVHTNATIRNTEFTVPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEIPDLEL 23076
Query: 1816 PTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTG---PMKEINLAPDSSSVVVSG 1872
DLK T S + V ++G V K G + I +S S+++
Sbjct: 23077 ADDLKKTVTIRAGASLRLM---VSVSGRPPPVITWSKQGIDLASRAIIDTTESYSLLI-- 23131
Query: 1873 LMVATKYEVSVYALKDTLTS--RPAQGVVTTLENVSPPRRARVTDATETTITISWRTKT- 1929
+ +Y+ Y ++ S + A +V + P +V + + ++TI+W T
Sbjct: 23132 VDKVNRYDAGKYTIEAENQSGKKSATVLVKVYDTPGPCPSVKVKEVSRDSVTITWEIPTI 23191
Query: 1930 ---ETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKI-----YLYTLNDNA 1981
+ + V+ A + T K Y I+GL GT Y +Y + +
Sbjct: 23192 DGGAPVNNYIVEKREAAMRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYGIGEPC 23251
Query: 1982 RSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPP----RARITGYIIKYEKPGSPPRE 2037
+S V+ + + P+ L + T +++ ++W+ P +R+TGY+++ K G+
Sbjct: 23252 ETSDAVLVSEVPL-VPAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGTERWM 23310
Query: 2038 VVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEP-----LIGRKKTDELP--QLVT 2090
V +P V E T+T L G +Y + A SEP + + LP L T
Sbjct: 23311 KVVTLKPTVLEHTVTSLNEGEQYLFRIRAQNEKGVSEPRETVTAVTVQDLRVLPTIDLST 23370
Query: 2091 LPHPNLHGP 2099
+P +H P
Sbjct: 23371 MPQKTIHVP 23379
Score = 123 bits (309), Expect = 2e-27
Identities = 310/1432 (21%), Positives = 508/1432 (35%), Gaps = 230/1432 (16%)
Query: 814 PPDPT-VDQVDDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTLS 868
PP P + V + W+ P +PI Y + + T ++ + +
Sbjct: 14103 PPGPVEISNVSAEKATLTWTPPLEDGGSPIKSYILEKRETSRLLWTVVSEDIQSCRHVAT 14162
Query: 869 DLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVE-VTDVKVTIMW 927
L G +Y + AV + PV Q E P P + V VT T+ W
Sbjct: 14163 KLIQGNEYIFRVSAVNHYGKGEPV--QSEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSW 14220
Query: 928 TPPE----SAVTGYRVDVIPV-NLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSH 982
P S +TGY V+ +L + P+S + +VTGL G TY F+V A +
Sbjct: 14221 KRPVDDGGSEITGYHVERREKKSLRWVRAIKTPVS-DLRCKVTGLQEGSTYEFRVSAENR 14279
Query: 983 GRESKPLTAQQTTKL-DA------PTNLQFVNETDSTVLVRWTPPR----AQITGYRLTV 1031
P A + + DA P+N + T + + W P +ITGY +
Sbjct: 14280 AGIGPPSEASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLAWGKPHYDGGLEITGYVVEH 14339
Query: 1032 GLTRRGQPRQYNVGPS--VSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGS 1089
+ G + ++++ + +LQ +Y + AI A +
Sbjct: 14340 QKVGDEAWIKDTTGTALRITQFVVPDLQTKEKYNFRISAINDAGVGEPAVIPDVEIVERE 14399
Query: 1090 SIPPY--NTEVTETTIVITWTPAPRIGFKLGVR-PSQGGEAPREVTSDSGSIVVSG---- 1142
P + + E+ T +V R G + + P +G AP EVT +I +
Sbjct: 14400 MAPDFELDAELRRTLVV-------RAGLSIRIFVPIKGRPAP-EVTWTKDNINLKNRANI 14451
Query: 1143 ---------LTPGVEYVYT---IQVLRDGQERDAPIVN-KVVTPLSPPTNLH-LEANPDT 1188
+ P T + + + + + VN +V+ P NL + D+
Sbjct: 14452 ENTESFTLLIIPECNRYDTGKFVMTIENPAGKKSGFVNVRVLDTPGPVLNLRPTDITKDS 14511
Query: 1189 GVLTVSWERSTTPD---ITGYRITTTPTNGQQGNSLEEVVHADQSSCTFD--NLSPGLEY 1243
+T+ W+ IT Y + + ++ H CT+ LS G EY
Sbjct: 14512 --VTLHWDLPLIDGGSRITNYIVEKREATRKSYSTATTKCH----KCTYKVTGLSEGCEY 14565
Query: 1244 NVSV-----YTVKDDKESV-PISDTIIPEVPQLTDLSFVDITDSSIGLRWTPLN---SST 1294
V Y + + E+ P+ + P P L+ +DIT S++ L W S
Sbjct: 14566 FFRVMAENEYGIGEPTETTEPVKASEAPSPPD--SLNIMDITKSTVSLAWPKPKHDGGSK 14623
Query: 1295 IIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLE-------PGIDYDISVITLINGGES 1347
I GY I G D TV GLE G +Y V+ + + G S
Sbjct: 14624 ITGYVIEAQRKGS---------DQWTHITTVKGLECVVRNLTEGEEYTFQVMAVNSAGRS 14674
Query: 1348 APT----TLTQQTAVPPPTDLR-------FTNIGPDT---MRVTWAPPPSIDLTNFLVRY 1393
AP + ++ + P DLR G + + V P P++
Sbjct: 14675 APRESRPVIVKEQTMLPELDLRGIYQKLVIAKAGDNIKVEIPVLGRPKPTVTW------- 14727
Query: 1394 SPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGL---- 1449
K + + + + + + +L E V S S Y PL R G
Sbjct: 14728 ---KKGDQILKQTQRVNFETTATSTILNINECVRSDSGPY------PLTARNIVGEVGDV 14778
Query: 1450 ---------DSPTG-IDFSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPRED 1495
PTG I F +++++ T W P I+ Y + S E
Sbjct: 14779 ITIQVHDIPGPPTGPIKFDEVSSDFVTFSWDPPENDGGVPISNYVVEMRQTD-STTWVEL 14837
Query: 1496 RVPHSRNSITLTNLTPGTEYVVSIVALN------GREESPLLIGQQSTVSDVPRDLEVVA 1549
R + T LT G EY + A N G + ++ V P +V A
Sbjct: 14838 ATTVIRTTYKATRLTTGLEYQFRVKAQNRYGVGPGITSACIVANYPFKVPGPPGTPQVTA 14897
Query: 1550 ATPTSLLISWDAP----AVTVRYYRITYGETGGN--SPVQEFTVPGSKSTATISGLKPGV 1603
T S+ ISW P + Y + E G V + VPG+ + SGL G+
Sbjct: 14898 VTKDSMTISWHEPLSDGGSPILGYHVERKERNGILWQTVSKALVPGNIFKS--SGLTDGI 14955
Query: 1604 DYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKW----LPSSSP 1659
Y V A G S S + ID P + ++ +++++KW
Sbjct: 14956 AYEFRVIAENMAGKSKPSKPSEPMLALDPIDPPGKPVPLNITRHTVTLKWAKPEYTGGFK 15015
Query: 1660 VTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQ-- 1717
+T Y V K + + E T+ GL Y V A+N +G P +
Sbjct: 15016 ITSYIVEKRDLPNGRWLKANFSNILENEFTVSGLTEDAAYEFRVIAKNAAGAISPPSEPS 15075
Query: 1718 TAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDT 1777
A+T D DV+ IK+ + + + + D P + +D
Sbjct: 15076 DAITCRD--------DVEAPKIKVDVKFKDTVILKAGEAFRLEADVSGRPPPTMEWSKDG 15127
Query: 1778 AELQGL---------------------RPGSEYTVSVVALHDDMESQPLIGTQSTAIPAP 1816
EL+G R YT++ A + ++ + + P P
Sbjct: 15128 KELEGTAKLEIKIADFSTNLVNKDSTRRDSGAYTLT--ATNPGGFAKHIFNVKVLDRPGP 15185
Query: 1817 TD--LKFTQVTPTSLSAQWTPP----NVQLTGYRVRVTPKEKTGPMKEINLAPD--SSSV 1868
+ L T+VT W PP ++ Y + K +T + N+A + + +
Sbjct: 15186 PEGPLAVTEVTSEKCVLSWFPPLDDGGAKIDHY---IVQKRETSRLAWTNVASEVQVTKL 15242
Query: 1869 VVSGLMVATKY-----EVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITI 1923
V+ L+ +Y V+ Y + + L S P V PP+ VT T+ ++ +
Sbjct: 15243 KVTKLLKGNEYIFRVMAVNKYGVGEPLESEPVL-AVNPYGPPDPPKNPEVTTITKDSMVV 15301
Query: 1924 SW----RTKTETITGFQVDAVPANGQTPIQRTIK--PDVRSYTITGLQPGTDYKIYLYTL 1977
W I + V+ GQ I+ K D+R Y ++GL G +Y+ +
Sbjct: 15302 CWGHPDSDGGSEIINYIVERRDKAGQRWIKCNKKTLTDLR-YKVSGLTEGHEYEFRIMAE 15360
Query: 1978 NDNARSSP-------VVIDASTAIDAPSNLRFLATTPNSLLVSWQPP----RARITGYII 2026
N S+P D P N R L T+ +S+ ++W P + ITGY++
Sbjct: 15361 NAAGISAPSPTSPFYKACDTVFKPGPPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMV 15420
Query: 2027 KYEKPGSPPREVVPRPRP-GVTEATITGLEPGTEYTIYVIALKNNQKSEPLI 2077
+ P ++V P T TITGL EY I + A+ + EP +
Sbjct: 15421 EIALPEEDEWQIVTPPAGLKATSYTITGLTENQEYKIRIYAMNSEGLGEPAL 15472
Score = 123 bits (309), Expect = 2e-27
Identities = 338/1634 (20%), Positives = 602/1634 (36%), Gaps = 228/1634 (13%)
Query: 613 EVFITETPSQPNSHP-----------IQWNAPQ---PSHISKYILRWRPKNSVGRWKEAT 658
E ++ P P P +QW P S I+ YI+ R GRW +A+
Sbjct: 17141 ECYVARDPCDPPGTPEPIMVKRNEITLQWTKPVYDGGSMITGYIVEKRDLPD-GRWMKAS 17199
Query: 659 IPGHLNS-YTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTP 717
+ + +T+ GL YE ++I+ G + S ST +T +
Sbjct: 17200 FTNVIETQFTVSGLTEDQRYEFRVIAKNAAGA-------ISKPSDST----GPITAKDEV 17248
Query: 718 FSPLVATSESVTEITASSFVVSWVSASD-------TVSGFRVEYELSEEGD-EPQYLDLP 769
P ++ + + ++ +D T+ R + E+ E E + D
Sbjct: 17249 ELPRISMDPKFRDTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFK 17308
Query: 770 STATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPT-VDQVDDTSIV 828
+ V + G +YI+ ++ G +S ++ P P P V V
Sbjct: 17309 ALLI-VKDAIRIDGGQYILRASNVA--GSKSFPVNVKVLDRPGPPEGPVQVTGVTSEKCS 17365
Query: 829 VRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITI---- 880
+ WS P + I+ Y + + + T + NS+ ++ L G +Y I
Sbjct: 17366 LTWSPPLQDGGSDISHYVVEKRETSRLAWTVVASEVVTNSLKVTKLLEGNEYVFRIMAVN 17425
Query: 881 -YAVEENQESTPVVIQQETTGTPRSDTVPSP-RDLQFVEVTDVKVTIMWTPPES----AV 934
Y V E ES PV+++ +P P + L+ + +T+ W P+S +
Sbjct: 17426 KYGVGEPLESAPVLMKNPFV-------LPGPPKSLEVTNIAKDSMTVCWNRPDSDGGSEI 17478
Query: 935 TGYRV---DVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTA 991
GY V D + + +R+ R VTGL+ Y F+V A + +P A
Sbjct: 17479 IGYIVEKRDRSGIRWIKCNKRRITDLR---LRVTGLTEDHEYEFRVSAENAAGVGEPSPA 17535
Query: 992 -------QQTTKLDAPTNLQFVNETDSTVLVRWTPP----RAQITGYRLTVGLTRRGQPR 1040
K PTN V+ T +++ + W P ++I GY V + + +
Sbjct: 17536 TVYYKACDPVFKPGPPTNAHIVDTTKNSITLAWGKPIYDGGSEILGY--VVEICKADEEE 17593
Query: 1041 QYNVGPS----VSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNT 1096
V P V+++ + L EY + + A+ +AT V T++P +
Sbjct: 17594 WQIVTPQTGLRVTRFEISKLTEHQEYKIRVCALN-KVGLGEATSVPGTVKPEDKLEAPEL 17652
Query: 1097 EVTETT---IVITWTPAPRIGFKLGVRPS-------QGGEAPREVTSDSG----SIVVSG 1142
++ IV+ + RI RP+ + GE +V + G + +
Sbjct: 17653 DLDSELRKGIVVRAGGSARIHIPFKGRPTPEITWSREEGEFTDKVQIEKGVNYTQLSIDN 17712
Query: 1143 LTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHL-EANPDTGVLTVSWERSTTP 1201
Y +++ + A + KV+ PP NL + E D+ L WE P
Sbjct: 17713 CDRNDAGKYILKLENSSGSKSAFVTVKVLDTPGPPQNLAVKEVRKDSAFLV--WE---PP 17767
Query: 1202 DITGYRITTTPTNGQQGNSLEEVVHAD----QSSCTFDNLSPGLEYNVSVYTVKDDKESV 1257
I G ++ ++ + + ++S +NL+ G Y V + V
Sbjct: 17768 IIDGGAKVKNYVIDKRESTRKAYANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFGVGV 17827
Query: 1258 PIS--DTIIPEVPQLTD--LSFVDITDSSIGLRWTPLN---SSTIIGYRITVVAAGEGIP 1310
P+ D + P ++ D++ +S L W S ++GY V +G
Sbjct: 17828 PVETVDAVKAAEPPSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLGY--VVEMQPKGTE 17885
Query: 1311 IFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTT---------LTQQTAVPPP 1361
+ +S V VTGL G +Y V G+S P LT Q ++ P
Sbjct: 17886 KWSIVAESKVCNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKLP 17945
Query: 1362 TDLRFTNIGPD---TMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTN 1418
+ G D + V P P+I +++ P+K +++ + + VL +
Sbjct: 17946 FNTYSIQAGEDLKIEIPVIGRPRPNI---SWVKDGEPLK---QTTRVNVEETATSTVL-H 17998
Query: 1419 LLPGTE------YVVSVSSVYEQHESTPLRGRQKTGLDSPTG-IDFSDITANSFTVHWIA 1471
+ G + V + +S E+ + +K G P G + F +++A+ + W
Sbjct: 17999 IKEGNKDDFGKYTVTATNSAGTATENLSVIVLEKPG--PPVGPVRFDEVSADFVVISWEP 18056
Query: 1472 PRAT----ITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREE 1527
P T I+ Y + + + +R +I +T L GTEY I A N +
Sbjct: 18057 PAYTGGCQISNYIVEKR-DTTTTTWHMVSATVARTTIKITKLKTGTEYQFRIFAENRYGK 18115
Query: 1528 SPLLIGQQSTVS------DVPRDLEVVAATPTSLLISWDAP----AVTVRYYRITYGETG 1577
S L + V P V + + +L+ W P + Y + E
Sbjct: 18116 SAPLDSKAVIVQYPFKEPGPPGTPFVTSISKDQMLVQWHEPVNDGGTKIIGYHLEQKEKN 18175
Query: 1578 GNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPS 1637
V+ P + +GL G++Y V A G S R D P
Sbjct: 18176 SILWVKLNKTPIQDTKFKTTGLDEGLEYEFKVSAENIVGIGKPSKVSECFVARDPCDPPG 18235
Query: 1638 QMQVTDVQDNSISVKW----LPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGL 1693
+ + + N++++KW S +TGY V K +TE T+ GL
Sbjct: 18236 RPEAIVITRNNVTLKWKKPAYDGGSKITGYIVEKKDLPDGRWMKASFTNVLETEFTVSGL 18295
Query: 1694 QPTVEYVVSVYAQNPSGE-SQPLVQT-AVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVS 1751
Y V A+N +G S+P + A+T D ++D + + + V
Sbjct: 18296 VEDQRYEFRVIARNAAGNFSEPSDSSGAITARD--------EIDAPNASLDPKYKDVIVV 18347
Query: 1752 RYRVTYSSPED----GIHELFPAPDGE--EDTAELQGLRPGSEYTVSVV--ALHDD---- 1799
T+ D I ++ + DG+ E+TA ++ + T VV + D
Sbjct: 18348 HAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQY 18407
Query: 1800 -MESQPLIGTQSTAI-------PAPTD--LKFTQVTPTSLSAQWTPPNVQLTGYRVR--V 1847
++ + GT+S I P P + LK T VT W PP +Q G + +
Sbjct: 18408 ILKLSNVGGTKSIPITVKVLDRPGPPEGPLKVTGVTAEKCYLAWNPP-LQDGGANISHYI 18466
Query: 1848 TPKEKTGPMK--EINLAPDSSSVVVSGLMVATKY-----EVSVYALKDTLTSRPAQGVVT 1900
K +T + +++ + + V+ L+ +Y V+ Y + + L S P
Sbjct: 18467 IEKRETSRLSWTQVSTEVQALNYKVTKLLPGNEYIFRVMAVNKYGIGEPLESGPVT-ACN 18525
Query: 1901 TLENVSPPRRARVTDATETTITISWRTKTE----TITGFQVDAVPANG--QTPIQRTIKP 1954
+ PP V+ T+ ++ ++W + I G+ ++ G T +
Sbjct: 18526 PYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDKEGVRWTKCNKKTLT 18585
Query: 1955 DVRSYTITGLQPGTDYKIYLYTLNDNARSSPV-------VIDASTAIDAPSNLRFLATTP 2007
D+R +TGL G Y+ + N P DA PSN + T+
Sbjct: 18586 DLR-LRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRACDALYPPGPPSNPKVTDTSR 18644
Query: 2008 NSLLVSWQPP----RARITGYIIKYEKPGSPPREVVPRPRPGV--TEATITGLEPGTEYT 2061
+S+ ++W P A + GY+++ K + P G+ + T+T L+ TEY
Sbjct: 18645 SSVSLAWSKPIYDGGAPVKGYVVEV-KEAAADEWTTCTPPTGLQGKQFTVTKLKENTEYN 18703
Query: 2062 IYVIALKNNQKSEP 2075
+ A+ + EP
Sbjct: 18704 FRICAINSEGVGEP 18717
Score = 123 bits (309), Expect = 2e-27
Identities = 314/1502 (20%), Positives = 546/1502 (36%), Gaps = 190/1502 (12%)
Query: 619 TPSQPNSHPIQWNAP---QPSHISKYILRWRPKNSVGRWKEATIPGHLNS--YTIKGLKP 673
T + +S + W+ P + + Y++ + + + W T P L +T+ LK
Sbjct: 18640 TDTSRSSVSLAWSKPIYDGGAPVKGYVVEVK-EAAADEWTTCTPPTGLQGKQFTVTKLKE 18698
Query: 674 GVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITA 733
Y ++ +I G E T + V + P L A V + A
Sbjct: 18699 NTEYNFRICAINSEGVGE------PATLPGSVVAQERIE---PPEIELDADLRKVVVLRA 18749
Query: 734 SSFVVSWVSASDTVSGFRVEYELSEEGDEP-----QYLDLPSTATSVNIPDLLPGRKYIV 788
S+ + +V T+ G R E E+ E E +++ S+ T + I ++
Sbjct: 18750 SATLRLFV----TIKG-RPEPEVKWEKAEGILTDRAQIEVTSSFTMLVIDNVTRFDSGRY 18804
Query: 789 NVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ----APITGYRIV 844
N+ + G ++ ++ +P AP + T+ +V S+ + W P A IT Y +
Sbjct: 18805 NLTLENNSGSKTAFVNVRVLDSPSAPVNLTIREVKKDSVTLSWEPPLIDGGAKITNYIVE 18864
Query: 845 YSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRS 904
+ + + T + + +LQ G Y + A E P ETT +
Sbjct: 18865 KRETTRKAYATITNNCTKTTFRIENLQEGCSYYFRVLASNEYGIGLPA----ETTEPVKV 18920
Query: 905 DTVPSPRD-LQFVEVTDVKVTIMWTPPES----AVTGYRVDVIPVNLPGEHGQRLPISRN 959
P P + V+VT TI W PES +TGY V++ E +
Sbjct: 18921 SEPPLPPGRVTLVDVTRNTATIKWEKPESDGGSKITGYVVEMQTKG--SEKWSTCTQVKT 18978
Query: 960 TFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWT- 1018
A ++GL+ G Y F+V AV+ S P +L P + + S L T
Sbjct: 18979 LEATISGLTAGEEYVFRVAAVNEKGRSDP------RQLGVPVIARDIEIKPSVELPFHTF 19032
Query: 1019 --PPRAQIT-------GYRLTVGLTRRGQP----RQYNVGPSVSKYPLRNLQPASEYTVS 1065
R Q+ + TV + GQ + NV S + L +++ AS+ V
Sbjct: 19033 NVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSL-SIKEASKEDVG 19091
Query: 1066 LVAIKGNQESPKATGVFTTL---QPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPS 1122
+ + + T T + +PG P EV+ +I I+W P G G + S
Sbjct: 19092 TYELCVSNSAGSITVPITIIVLDRPGPPGPIRIDEVSCDSITISWNPPEYDG---GCQIS 19148
Query: 1123 QGGEAPREVTSDSGSIV----------VSGLTPGVEYVYTIQVL-RDGQ----ERDAPIV 1167
+E TS + IV + LT G EY + + R G+ E A +
Sbjct: 19149 NYIVEKKETTSTTWHIVSQAVARTSIKIVRLTTGSEYQFRVCAENRYGKSSYSESSAVVA 19208
Query: 1168 NKVVTPLSPP-TNLHLEANPDTGVLTVSWERSTTPD---ITGYRITTTPTNGQQGNSLEE 1223
+P PP T + A T + V+W+ + GY + + + +
Sbjct: 19209 EYPFSPPGPPGTPKVVHATKST--MLVTWQVPVNDGGSRVIGYHLEYKERSSILWSKANK 19266
Query: 1224 VVHADQSSCTFDNLSPGLEYNVSVYT--------VKDDKESVPISDTIIPE-VPQLTDLS 1274
++ AD + L GL Y VY E VP D P P++T+
Sbjct: 19267 ILIAD-TQMKVSGLDEGLMYEYRVYAENIAGIGKCSKSCEPVPARDPCDPPGQPEVTN-- 19323
Query: 1275 FVDITDSSIGLRWTPLN---SSTIIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPG 1331
IT S+ L+W+ + + I GY + +G + ++ + Y+ VT L
Sbjct: 19324 ---ITRKSVSLKWSKPHYDGGAKITGYIVERRELPDGRWLKCNYTNIQETYFEVTELTED 19380
Query: 1332 IDYDISVI------TLINGGESAPTTLTQQTAVPPPT--DLRFTNI----GPDTMRVT-- 1377
Y+ V ++ ES + + PP D++F ++ + +++
Sbjct: 19381 QRYEFRVFARNAADSVSEPSESTGPIIVKDDVEPPRVMMDVKFRDVIVVKAGEVLKINAD 19440
Query: 1378 --WAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNL----LPGTEYVVSVSS 1431
P P I + E+ A I +DN +LT +YV+++ +
Sbjct: 19441 IAGRPLPVISWAKDGIEI------EERARTEIISTDNHTLLTVKDCIRRDTGQYVLTLKN 19494
Query: 1432 VYEQHE-STPLRGRQKTGLDSPTG-IDFSDITANSFTVHWIAPR----ATITGYRI-RHH 1484
V + + K G P G ++ + +TA ++ W P+ A I Y + +
Sbjct: 19495 VAGTRSVAVNCKVLDKPG--PPAGPLEINGLTAEKCSLSWGRPQEDGGADIDYYIVEKRE 19552
Query: 1485 PEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGR------EESPLLIGQQSTV 1538
H + E + S +T L G EY+ + +N E + TV
Sbjct: 19553 TSHLAWTICEGEL--QMTSCKVTKLLKGNEYIFRVTGVNKYGVGEPLESVAIKALDPFTV 19610
Query: 1539 SDVPRDLEVVAATPTSLLISWDAP----AVTVRYYRITYGETGGNSPVQEFTVPGSKSTA 1594
P LE+ + T S+ + W P + Y I E V+ P
Sbjct: 19611 PSPPTSLEITSVTKESMTLCWSRPESDGGSEISGYIIERREKNSLRWVRVNKKPVYDLRV 19670
Query: 1595 TISGLKPGVDYTITVYAVTGRGDS-PASSKPISINYRTEI---DKPSQMQVTDVQDNSIS 1650
+GL+ G +Y VYA G S P+ + P+ I + PS+ ++ D +I+
Sbjct: 19671 KSTGLREGCEYEYRVYAENAAGLSLPSETSPL-IRAEDPVFLPSPPSKPKIVDSGKTTIT 19729
Query: 1651 VKWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQ 1706
+ W+ +P+TGY V K+ KT TE TI GL EYV V +
Sbjct: 19730 IAWVKPLFDGGAPITGYTVEYK-KSDDTDWKTSIQSLRGTEYTISGLTTGAEYVFRVKSV 19788
Query: 1707 NPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRY---------RVTY 1757
N G S P + + D+D + K + V +
Sbjct: 19789 NKVGASDPSDSSDPQIAKEREEEPLFDIDSEMRKTLIVKAGASFTMTVPFRGRPVPNVLW 19848
Query: 1758 SSPEDGIHELFPAPDGEEDTA---ELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIP 1814
S P+ + + T+ E +YT+++ + ++ T P
Sbjct: 19849 SKPDTDLRTRAYVDTTDSRTSLTIENANRNDSGKYTLTIQNVLSAASLTLVVKVLDTPGP 19908
Query: 1815 APTDLKFTQVTPTSLSAQWTPP----NVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVV 1870
PT++ VT S W P + Y + K + N + S V
Sbjct: 19909 -PTNITVQDVTKESAVLSWDVPENDGGAPVKNYHIEKREASKKAWVSVTNNC-NRLSYKV 19966
Query: 1871 SGLMVATKYEVSVYALKDTLTSRPA---QGVVTTLENVSPPRRARVTDATETTITISW-- 1925
+ L Y V + PA +GV T E SPP + VT ++ +++++W
Sbjct: 19967 TNLQEGAIYYFRVSGENEFGVGIPAETKEGVKIT-EKPSPPEKLGVTSISKDSVSLTWLK 20025
Query: 1926 --RTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARS 1983
I + V+A+ + ++ + + ++GL+ ++Y ++ N S
Sbjct: 20026 PEHDGGSRIVHYVVEALEKGQKNWVKCAVAKSTH-HVVSGLRENSEYFFRVFAENQAGLS 20084
Query: 1984 SP 1985
P
Sbjct: 20085 DP 20086
Score = 120 bits (301), Expect = 2e-26
Identities = 286/1368 (20%), Positives = 511/1368 (37%), Gaps = 206/1368 (15%)
Query: 866 TLSDLQPGVQYNITIYAVEENQEST-PVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVT 924
T++ L G +Y + A EN+ T P + + D P + +V+ ++T
Sbjct: 11984 TVTRLIEGNEYIFRVRA--ENKIGTGPPTESKPVIAKTKYDKPGRPDPPEVTKVSKEEMT 12041
Query: 925 IMWTPPE----SAVTGYRVDVIPVNLPGEHGQR-LPISRNTFAE----VTGLSPGVTYYF 975
++W PPE ++TGY ++ +H R +P++++ E V L P Y F
Sbjct: 12042 VVWNPPEYDGGKSITGYFLEK-----KEKHSTRWVPVNKSAIPERRMKVQNLLPDHEYQF 12096
Query: 976 KVFAVSH------GRESKPLTAQQTTKLDAP-TNLQFVNETDSTVLVRWTPP----RAQI 1024
+V A + S+P+ A+ + P TN + V+ T ++ + W P A I
Sbjct: 12097 RVKAENEIGIGEPSLPSRPVVAKDPIEPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAPI 12156
Query: 1025 TGY------RLTVGLTRRGQPRQYNVGPSVSK-YPLRNLQPASEYTVSL-----VAIKGN 1072
GY ++ G R V K + + +L EY + V I
Sbjct: 12157 IGYVVEMRPKIADASPDEGWKRCNAAAQLVRKEFTVTSLDENQEYEFRVCAQNQVGIGRP 12216
Query: 1073 QESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWT-------------PAPRIGFKLGV 1119
E +A L+P P + + + +VI PAP++ ++
Sbjct: 12217 AELKEAIKPKEILEP----PEIDLDASMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVG 12272
Query: 1120 RPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTN 1179
+ + ++ +V+ T Y++ ++ E+ + +V+ P ++
Sbjct: 12273 IDNVVRKGQVDLVDTMAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFVNVRVLDTPGPVSD 12332
Query: 1180 LHLEANPDTGVLTVSW---ERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDN 1236
L + T VSW E +T Y + + + +++ V ++S N
Sbjct: 12333 LKVSDVTKTSC-HVSWAPPENDGGSQVTHYIVEKREADRKTWSTVTPEVK--KTSFHVTN 12389
Query: 1237 LSPGLEYNVSVYTVKDDKESVPI--------SDTII-PEVPQLTDLSFVDITDSSIGLRW 1287
L PG EY V V + VP SD + P+ P+ L ++T +S L W
Sbjct: 12390 LVPGNEYYFRVTAVNEYGPGVPTDVPKPVLASDPLSEPDPPR--KLEVTEMTKNSATLAW 12447
Query: 1288 TPL---NSSTIIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLING 1344
P + I GY + + + ++ VTGL+ G Y V
Sbjct: 12448 LPPLRDGGAKIDGYITSYREEEQPADRWTEYSVVKDLSLVVTGLKEGKKYKFRVAARNAV 12507
Query: 1345 GESAPTTL-----TQQTAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVK-- 1397
G S P ++ +PP + P+ + + I+ + + K
Sbjct: 12508 GVSLPREAEGVYEAKEQLLPPKI------LMPEQITIKAGKKLRIEAHVYGKPHPTCKWK 12561
Query: 1398 -NEEDV---AELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSP- 1452
E++V + L++ +D++ +L + S E T + + +D+P
Sbjct: 12562 KGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPG 12621
Query: 1453 ---TGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPH----SRNSIT 1505
D SDI A++ ++ W P G I ++ R D V ++ S
Sbjct: 12622 PPQPPFDISDIDADACSLSWHIPLED-GGSNITNYIVEKCDVSRGDWVTALASVTKTSCR 12680
Query: 1506 LTNLTPGTEYVVSIVALN--GREE---SPLLIGQ-QSTVSDVPRDLEVVAATPTSLLISW 1559
+ L PG EY+ + A N G E SP ++ Q V P++ V + ++W
Sbjct: 12681 VGKLIPGQEYIFRVRAENRFGISEPLTSPKMVAQFPFGVPSEPKNARVTKVNKDCIFVAW 12740
Query: 1560 DAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATI----------------SGLKPGV 1603
D P ++ G SP+ + + + + + +GL G+
Sbjct: 12741 DRP------------DSDGGSPIIGYLIERKERNSLLWVKANDTLVRSTEYPCAGLVEGL 12788
Query: 1604 DYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWL----PSSSP 1659
+Y+ +YA+ G SP S + R +D P + +V DV +++S+ W S
Sbjct: 12789 EYSFRIYALNKAGSSPPSKPTEYVTARMPVDPPGKPEVIDVTKSTVSLIWARPKHDGGSK 12848
Query: 1660 VTGYRVTTTPKNGPGPTKTKTAGPD--QTEMTIEGLQPTVEYVVSVYAQN------PSGE 1711
+ GY V G + TA Q E T GL+ +Y A+ PS
Sbjct: 12849 IIGYFVEACKLPGDKWVRCNTAPHQIPQEEYTATGLEEKAQYQFRAIARTAVNISPPSEP 12908
Query: 1712 SQP---LVQTAVTNIDRPKGL-------AFTDVDVDSIKIAWESPQGQVS-RYRVTYSSP 1760
S P L + ID + A T+V +D+ + P VS + T P
Sbjct: 12909 SDPVTILAENVPPRIDLSVAMKSLLTVKAGTNVCLDA--TVFGKPMPTVSWKKDGTLLKP 12966
Query: 1761 EDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPA-PTDL 1819
+GI A T EL + ++ A + I + P P +
Sbjct: 12967 AEGIK---MAMQRNLCTLELFSVNRKDSGDYTITAENSSGSKSATIKLKVLDKPGPPASV 13023
Query: 1820 KFTQVTPTSLSAQWTPP----NVQLTGYRVRVTPKEKTGP-MKEINLAPDSSSVVVSGLM 1874
K ++ W PP ++T Y V +E + P +++ +S V L+
Sbjct: 13024 KINKMYSDRAMLSWEPPLEDGGSEITNY--IVDKRETSRPNWAQVSATVPITSCSVEKLI 13081
Query: 1875 VATKYEVSV-----YALKDTLTSRPAQGVVTTLENVSPPRRAR---VTDATETTITISWR 1926
+Y+ + Y + D + + PA PP R +++ T+ +T+SW+
Sbjct: 13082 EGHEYQFRICAENKYGVGDPVFTEPA----IAKNPYDPPGRCDPPVISNITKDHMTVSWK 13137
Query: 1927 TKTE----TITGFQVDAVPANGQTPIQRTIKPDV-RSYTITGLQPGTDYKIYLYTLNDNA 1981
+ ITG+ ++ + KP + R+ TGLQ GT+Y+ + +N
Sbjct: 13138 PPADDGGSPITGYLLEKRETQAVNWTKVNRKPIIERTLKATGLQEGTEYEFRVTAINKAG 13197
Query: 1982 RSSPVVIDASTAIDA---------PSNLRFLATTPNSLLVSWQPPR----ARITGYIIKY 2028
P DAS A A P+ + TT +S+ +SW P + I GY+++
Sbjct: 13198 PGKP--SDASKAAYARDPQYPPGPPAFPKVYDTTRSSVSLSWGKPAYDGGSPIIGYLVEV 13255
Query: 2029 EKPGSPPREVVPRPRP-GVTEATITGLEPGTEYTIYVIALKNNQKSEP 2075
++ S P+ T +TGL T+Y V A+ S+P
Sbjct: 13256 KRADSDNWVRCNLPQNLQKTRFEVTGLMEDTQYQFRVYAVNKIGYSDP 13303
Score = 120 bits (301), Expect = 2e-26
Identities = 304/1512 (20%), Positives = 534/1512 (35%), Gaps = 204/1512 (13%)
Query: 718 FSPLVATSESVTEITASSFVVSW----VSASDTVSGFRVEYELSEEGDEPQYLDLPSTA- 772
F P T+ + + T +S ++W + G+ VE + + +E + P T
Sbjct: 17546 FKPGPPTNAHIVDTTKNSITLAWGKPIYDGGSEILGYVVE--ICKADEEEWQIVTPQTGL 17603
Query: 773 --TSVNIPDLLPGRKYIVNVYQISEDG--EQSLILSTSQTTAPDAPPDPTVDQVDDTSIV 828
T I L ++Y + V +++ G E + + T + P+ +D IV
Sbjct: 17604 RVTRFEISKLTEHQEYKIRVCALNKVGLGEATSVPGTVKPEDKLEAPELDLDSELRKGIV 17663
Query: 829 VRW---SRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYN-ITIYAVE 884
VR +R P G +P + S E + ++ GV Y ++I +
Sbjct: 17664 VRAGGSARIHIPFKGRP---TPEITWSREEGEFTDKVQ------IEKGVNYTQLSIDNCD 17714
Query: 885 ENQESTPVVIQQETTGTPRS-------DTVPSPRDLQFVEVTDVKVTIMWTPP----ESA 933
N ++ + ++G+ + DT P++L EV ++W PP +
Sbjct: 17715 RNDAGKYILKLENSSGSKSAFVTVKVLDTPGPPQNLAVKEVRKDSAFLVWEPPIIDGGAK 17774
Query: 934 VTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQ 993
V Y +D S+ +F +V L+ G YYF+V A + P+
Sbjct: 17775 VKNYVIDKRESTRKAYANVSSKCSKTSF-KVENLTEGAIYYFRVMAENEFGVGVPVETVD 17833
Query: 994 TTKLDAPTN------LQFVNETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYN 1043
K P + L V++T ++++ W P +++ GY V + +G +
Sbjct: 17834 AVKAAEPPSPPGKVTLTDVSQTSASLM--WEKPEHDGGSRVLGY--VVEMQPKGTEKWSI 17889
Query: 1044 VGPS-VSKYPLRNLQPASEYTVSLVAIKGNQES-PKATGVFT-----TLQPGSSIPPYNT 1096
V S V + L EY + A +S P+ GV T+QP +P +NT
Sbjct: 17890 VAESKVCNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKLP-FNT 17948
Query: 1097 ------EVTETTIVITWTPAPRIGF-KLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEY 1149
E + I + P P I + K G Q E T+ S + +
Sbjct: 17949 YSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFG 18008
Query: 1150 VYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTP---DITGY 1206
YT+ + V+ PP + +SWE I+ Y
Sbjct: 18009 KYTVTATNSAGTATENLSVIVLEKPGPPVGPVRFDEVSADFVVISWEPPAYTGGCQISNY 18068
Query: 1207 RITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTII-- 1264
+ T + + V +++ L G EY ++ +S P+ +
Sbjct: 18069 IVEKRDTTTTTWHMVSATVA--RTTIKITKLKTGTEYQFRIFAENRYGKSAPLDSKAVIV 18126
Query: 1265 ---------PEVPQLTDLSFVDITDSSIGLRW-TPLNS--STIIGYRITVVAAGEGIPIF 1312
P P +T +S + ++W P+N + IIGY + + +
Sbjct: 18127 QYPFKEPGPPGTPFVTSIS-----KDQMLVQWHEPVNDGGTKIIGYHLEQKEKNSILWVK 18181
Query: 1313 EDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQ----QTAVPPPTDLRFTN 1368
+ + TGL+ G++Y+ V G P+ +++ + PP
Sbjct: 18182 LNKTPIQDTKFKTTGLDEGLEYEFKVSAENIVGIGKPSKVSECFVARDPCDPPGRPEAIV 18241
Query: 1369 IGPDTMRVTWAPPP---SIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEY 1425
I + + + W P +T ++V K+ D + S TN+L TE+
Sbjct: 18242 ITRNNVTLKWKKPAYDGGSKITGYIVEK---KDLPDGRWMKAS-------FTNVLE-TEF 18290
Query: 1426 VVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITG-YR---I 1481
VS V +Q + R G S ITA AP A++ Y+ +
Sbjct: 18291 TVS-GLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARD---EIDAPNASLDPKYKDVIV 18346
Query: 1482 RHHPEHF------SGRPREDRV--------------PHSRNSITLTNL-------TPGTE 1514
H E F G+P D V +++I T L T G +
Sbjct: 18347 VHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQ 18406
Query: 1515 YVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAP----AVTVRYYR 1570
Y++ + + G + P+ + L+V T ++W+ P + +Y
Sbjct: 18407 YILKLSNVGGTKSIPITVKVLDRPGPPEGPLKVTGVTAEKCYLAWNPPLQDGGANISHYI 18466
Query: 1571 ITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRG-DSPASSKPISI-N 1628
I ET S Q T + + ++ L PG +Y V AV G P S P++ N
Sbjct: 18467 IEKRETSRLSWTQVSTEVQALNYK-VTKLLPGNEYIFRVMAVNKYGIGEPLESGPVTACN 18525
Query: 1629 YRTEIDKPSQMQVTDVQDNSISVKWL----PSSSPVTGYRVTTTPKNGPGPTKTKTAGPD 1684
PS +V+ + +S+ V W + + GY + K G TK
Sbjct: 18526 PYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDKEGVRWTKCNKKTLT 18585
Query: 1685 QTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQT-------AVTNIDRPKGLAFTDVDVD 1737
+ + GL Y V A+N +G +P + A+ P TD
Sbjct: 18586 DLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRACDALYPPGPPSNPKVTDTSRS 18645
Query: 1738 SIKIAWESP----QGQVSRYRVTYSSPEDGIHELFPAPDGEEDTA-ELQGLRPGSEYTVS 1792
S+ +AW P V Y V P G + + L+ +EY
Sbjct: 18646 SVSLAWSKPIYDGGAPVKGYVVEVKEAAADEWTTCTPPTGLQGKQFTVTKLKENTEYNFR 18705
Query: 1793 VVALHDDMESQPL-----IGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRV 1847
+ A++ + +P + Q P +L L A T R+ V
Sbjct: 18706 ICAINSEGVGEPATLPGSVVAQERIEPPEIELDADLRKVVVLRASAT--------LRLFV 18757
Query: 1848 TPKEKTGPM----KEINLAPDSSSVVVSGLMV------ATKYEVSVY--ALKDTLTSRPA 1895
T K + P K + D + + V+ T+++ Y L++ S+ A
Sbjct: 18758 TIKGRPEPEVKWEKAEGILTDRAQIEVTSSFTMLVIDNVTRFDSGRYNLTLENNSGSKTA 18817
Query: 1896 QGVVTTLENVSPPRRARVTDATETTITISWRTKT----ETITGFQVDAVPANGQTPIQRT 1951
V L++ S P + + + ++T+SW IT + V+ + T
Sbjct: 18818 FVNVRVLDSPSAPVNLTIREVKKDSVTLSWEPPLIDGGAKITNYIVEKRETTRKAYATIT 18877
Query: 1952 IKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAP----SNLRFLATTP 2007
++ I LQ G Y + N+ P + P + + T
Sbjct: 18878 NNCTKTTFRIENLQEGCSYYFRVLASNEYGIGLPAETTEPVKVSEPPLPPGRVTLVDVTR 18937
Query: 2008 NSLLVSWQPPRA----RITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIY 2063
N+ + W+ P + +ITGY+++ + GS + + EATI+GL G EY
Sbjct: 18938 NTATIKWEKPESDGGSKITGYVVEMQTKGSEKWSTCTQVK--TLEATISGLTAGEEYVFR 18995
Query: 2064 VIALKNNQKSEP 2075
V A+ +S+P
Sbjct: 18996 VAAVNEKGRSDP 19007
Score = 119 bits (298), Expect = 4e-26
Identities = 329/1550 (21%), Positives = 553/1550 (35%), Gaps = 222/1550 (14%)
Query: 601 PLQTYPSSSGPVEVFITETPSQPN-------SHPIQWNAPQ---PSHISKYILRWRPKNS 650
P +T P VF+ PS+P + I W P + I+ Y + ++ +
Sbjct: 19696 PSETSPLIRAEDPVFLPSPPSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEYKKSDD 19755
Query: 651 VGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNT 710
WK + YTI GL G Y ++ S+ + G + + +S P +
Sbjct: 19756 TD-WKTSIQSLRGTEYTISGLTTGAEYVFRVKSVNKVGASD-------PSDSSDPQIAKE 19807
Query: 711 VTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVS--GFRVEYELSEEGDEP----Q 764
E PL +E+ + V + S + TV G V L + D
Sbjct: 19808 REEE-----PLFDID---SEMRKTLIVKAGASFTMTVPFRGRPVPNVLWSKPDTDLRTRA 19859
Query: 765 YLDLPSTATSVNIPDLL--PGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQV 822
Y+D + TS+ I + KY + + + +L++ T P P + TV V
Sbjct: 19860 YVDTTDSRTSLTIENANRNDSGKYTLTIQNVLSAASLTLVVKVLDTPGP--PTNITVQDV 19917
Query: 823 DDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNI 878
S V+ W P+ AP+ Y I + + + + S +++LQ G Y
Sbjct: 19918 TKESAVLSWDVPENDGGAPVKNYHIEKREASKKAWVSVTNNCNRLSYKVTNLQEGAIYYF 19977
Query: 879 TIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAV 934
+ E P ++ G ++ P L ++ V++ W PE S +
Sbjct: 19978 RVSGENEFGVGIPAETKE---GVKITEKPSPPEKLGVTSISKDSVSLTWLKPEHDGGSRI 20034
Query: 935 TGYRVDVIPVNLPGEHGQR----LPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKP-- 988
Y V+ + E GQ+ ++++T V+GL Y+F+VFA + S P
Sbjct: 20035 VHYVVEAL------EKGQKNWVKCAVAKSTHHVVSGLRENSEYFFRVFAENQAGLSDPRE 20088
Query: 989 -LTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPS 1047
L + P + N TV VR G L V + G+P V S
Sbjct: 20089 LLLPVLIKEQLEPPEIDMKNFPSHTVYVR--------AGSNLKVDIPISGKPLP-KVTLS 20139
Query: 1048 VSKYPLR-NLQPASEYTV---------SLVAIKGNQESPKATGVFTTL---------QPG 1088
PL+ ++ +E T S+ A G E A TT +PG
Sbjct: 20140 RDGVPLKATMRFNTEITAENLTINLKESVTADAGRYEITAANSSGTTKAFINIVVLDRPG 20199
Query: 1089 SSI-PPYNTEVTETTIVITWTPAPRIG-------FKLGVRPSQGGEAPREVTSDSGSIVV 1140
P +++TE ++ + W P G L S T + V
Sbjct: 20200 PPTGPVVISDITEESVTLKWEPPKYDGGSQVTNYILLKRETSTAVWTEVSATVARTMMKV 20259
Query: 1141 SGLTPGVEYVYTIQV-----LRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSW 1195
LT G EY + I+ + D + V T PP+ + N +TV W
Sbjct: 20260 MKLTTGEEYQFRIKAENRFGISDHIDSACVTVKLPYTTPGPPSTPWV-TNVTRESITVGW 20318
Query: 1196 ERSTT---PDITGYRITTTPTNG---QQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYT 1249
+ + GY + N Q+ N L V+ T +S GL Y VY
Sbjct: 20319 HEPVSNGGSAVVGYHLEMKDRNSILWQKANKL--VIRTTHFKVT--TISAGLIYEFRVYA 20374
Query: 1250 V------KDDKESVPISDTIIPEVPQLTDLSFVDITDSSIGLRWTPL---NSSTIIGYRI 1300
K S P+ E P+ ++ DI+ +S+ L W S I GY +
Sbjct: 20375 ENAAGVGKPSHPSEPVLAIDACEPPR--NVRITDISKNSVSLSWQQPAFDGGSKITGYIV 20432
Query: 1301 TVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISV------------------ITLI 1342
+G F + + + ++GL Y+ V IT I
Sbjct: 20433 ERRDLPDGRWTKASFTNVTETQFIISGLTQNSQYEFRVFARNAVGSISNPSEVVGPITCI 20492
Query: 1343 N--GGE--SAPTTLTQQTAVPPPTD--LRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPV 1396
+ GG P T+ T LR G + W TN LV V
Sbjct: 20493 DSYGGPVIDLPLEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALV---CV 20549
Query: 1397 KNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTG-I 1455
+N D+A + I +D L Y + + + +T +R + P G I
Sbjct: 20550 ENTTDLASILIKDADR-------LNSGCYELKLRNAMGSASAT-IRVQILDKPGPPGGPI 20601
Query: 1456 DFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNS-------ITLTN 1508
+F +TA T+ W P A G +I H + + RV S S IT T
Sbjct: 20602 EFKTVTAEKITLLW-RPPADDGGAKITH---YIVEKRETSRVVWSMVSEHLEECIITTTK 20657
Query: 1509 LTPGTEYVVSIVALNGRE-----ESPLLIGQQSTVSDVPRDL-EVVAATPTSLLISWDAP 1562
+ G EY+ + A+N ES ++ + + V+ P + EV T S+ + W P
Sbjct: 20658 IIKGNEYIFRVRAVNKYGIGEPLESDSVVAKNAFVTPGPPGIPEVTKITKNSMTVVWSRP 20717
Query: 1563 A------VTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRG 1616
++ + ++ G V + T+ ++ T GL DY V AV G
Sbjct: 20718 IADGGSDISGYFLEKRDKKSLGWFKVLKETIRDTRQKVT--GLTENSDYQYRVCAVNAAG 20775
Query: 1617 DSPASSKPISINYRTEID---KPSQMQVTDVQDNSISVKW----LPSSSPVTGYRVTTTP 1669
P S ID P+++++ D +SI++ W S VTGY V
Sbjct: 20776 QGPFSEPSEFYKAADPIDPPGPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVVEIRQ 20835
Query: 1670 KNGPGPTKTKTAGPDQ-TEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKG 1728
T T G + TE + L+P V Y V A N +G+ +P+ +
Sbjct: 20836 GEEEEWTTVSTKGEVRTTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMN--EPVQAKDI 20893
Query: 1729 LAFTDVDVD-SIKIAWESPQGQVSRYRVTYSS--PEDGIHELFPAPDGEEDTAELQGLRP 1785
L ++D+D +++ + + G+ + + + P G + ++
Sbjct: 20894 LEAPEIDLDVALRTSVIAKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYSIENTDS 20953
Query: 1786 GSEYTVSVVALHDDME---------SQPLIGTQSTAI----PAPTDLKFTQVTPTSLSAQ 1832
S T+ V +D + +P T S + A L+ V+ +++
Sbjct: 20954 SSLLTIPQVTRNDTGKYILTIENGVGEPKSSTVSVKVLDTPAACQKLQVKHVSRGTVTLL 21013
Query: 1833 WTPPNVQLTGYRVRVTPKEKTGPMKEINLAP---DSSSVVVSGLMVATKYEVSVYALKDT 1889
W PP + + +++ + ++ S+S + L T + V A +
Sbjct: 21014 WDPPLIDGGSPIINYVIEKRDATKRTWSVVSHKCSSTSFKLIDLSEKTPFFFRVLAENEI 21073
Query: 1890 LTSRPAQGV--VTTLENVSPPRRARVTDATETTITISWRTKTE-----TITGFQVDAVPA 1942
P + V E +P R + D+T+T++ +SW TK + IT + V+
Sbjct: 21074 GIGEPCETTEPVKAAEVPAPIRDLSMKDSTKTSVILSW-TKPDFDGGSVITEYVVERKGK 21132
Query: 1943 NGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDAST 1992
QT I ++ L+ + + ++ N+ S PV I T
Sbjct: 21133 GEQTWSHAGISKTC-EIEVSQLKEQSVLEFRVFAKNEKGLSDPVTIGPIT 21181
Score = 118 bits (296), Expect = 6e-26
Identities = 330/1625 (20%), Positives = 588/1625 (36%), Gaps = 230/1625 (14%)
Query: 611 PVEVFITETPSQPNSHPIQWNAP---QPSHISKYILRWRPKNSVGRWKEATIPGHLNSYT 667
PV V + E +S + W P S I Y+++ R W T S+
Sbjct: 13418 PVNVTVKEISK--DSAYVTWEPPIIDGGSPIINYVVQKRDAERKS-WSTVTTECSKTSFR 13474
Query: 668 IKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSES 727
+ L+ G Y ++ + +YG + T + V TP P+V
Sbjct: 13475 VANLEEGKSYFFRVFAENEYGIGDPGE------------TRDAVKASQTP-GPVVDLK-- 13519
Query: 728 VTEITASSFVVSWVS----ASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPG 783
V ++ SS + W + G+ V++ L+EE + + S + + DL G
Sbjct: 13520 VRSVSKSSCSIGWKKPHSDGGSRIIGYVVDF-LTEENKWQRVMK--SLSLQYSAKDLTEG 13576
Query: 784 RKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWS---RPQAPITG 840
++Y V +E+GE + T PD + + D + + + R + PI G
Sbjct: 13577 KEYTFRVSAENENGEGTPSEITVVARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPIKG 13636
Query: 841 YRIVYSPSVE--------GSSTELNLPETANSVTLS--DLQPGV--QYNITIYAVEENQE 888
+PSV + T +++ +A + TL D Q +Y IT+ V +E
Sbjct: 13637 KP---APSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKE 13693
Query: 889 STPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPV 944
T I + G P T P ++F EVT +T+ W PP+ S +T Y ++
Sbjct: 13694 GT---ISIKVVGKPGIPTGP----IKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRD- 13745
Query: 945 NLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKV-----FAVSHGRESKPLTAQQTTKL-D 998
++ + + T VT L G+ Y F+V + V G +S+P+ A+ + D
Sbjct: 13746 SVNNKWVTCASAVQKTTFRVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVPD 13805
Query: 999 APTNLQFVNETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGP-SVSKYPL 1053
AP V+ +V + WT P+ + ITGY L ++ N P + + +
Sbjct: 13806 APPPPNIVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTPIRMRDFKV 13865
Query: 1054 RNLQPASEYTVSLVAI------KGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITW 1107
L EY ++AI K + S + PG P +T ++ + W
Sbjct: 13866 TGLTEGLEYEFRVMAINLAGVGKPSLPSEPVVALDPIDPPGK---PEVINITRNSVTLIW 13922
Query: 1108 T-PAPRIGFKL-------GVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDG 1159
T P G KL PS+ V + V+ L G +Y + I+
Sbjct: 13923 TEPKYDGGHKLTGYIVEKRDLPSKSWMKANHVNVPECAFTVTDLVEGGKYEFRIRAKNTA 13982
Query: 1160 QERDAPIVN----------KVVTPLSPPT---NLHLEANPDTGVLTV-----------SW 1195
AP + + T + PT L ++A DT VL SW
Sbjct: 13983 GAISAPSESTETIICKDEYEAPTIVLDPTIKDGLTIKAG-DTIVLNAISILGKPLPKSSW 14041
Query: 1196 ERS----TTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVK 1251
++ DIT +IT+TPT+ +++ D T +P + K
Sbjct: 14042 SKAGKDIRPSDIT--QITSTPTSSML--TIKYATRKDAGEYTITATNP--------FGTK 14089
Query: 1252 DDKESVPISDTIIPEVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGEGIPI 1311
+ V + D +P P ++S +++ L WTP + ++ E +
Sbjct: 14090 VEHVKVTVLD--VPGPPGPVEIS--NVSAEKATLTWTPPLEDGGSPIKSYILEKRETSRL 14145
Query: 1312 FEDFVDSSVG--YYTVTGLEPGIDYDISVITLINGG-----ESAPTTLTQQTAVP-PPTD 1363
V + + T L G +Y V + + G +S P + + P PP
Sbjct: 14146 LWTVVSEDIQSCRHVATKLIQGNEYIFRVSAVNHYGKGEPVQSEPVKMVDRFGPPGPPEK 14205
Query: 1364 LRFTNIGPDTMRVTWAPP---PSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLL 1420
+N+ +T V+W P ++T + V K+ V + SD +T L
Sbjct: 14206 PEVSNVTKNTATVSWKRPVDDGGSEITGYHVERREKKSLRWVRAIKTPVSDLRCKVTGLQ 14265
Query: 1421 PGTEYVVSVSSVYEQHESTPLRGRQKTGLDS-------PTGIDFSDITANSFTVHWIAPR 1473
G+ Y VS+ P + P+ +D T S ++ W P
Sbjct: 14266 EGSTYEFRVSAENRAGIGPPSEASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLAWGKPH 14325
Query: 1474 ----ATITGYRIRHHPEHFSGRPREDRVPHSR-NSITLTNLTPGTEYVVSIVALN--GRE 1526
ITGY + H ++ R + +L +Y I A+N G
Sbjct: 14326 YDGGLEITGYVVEHQKVGDEAWIKDTTGTALRITQFVVPDLQTKEKYNFRISAINDAGVG 14385
Query: 1527 ESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFT 1586
E ++ + ++ D E+ A +L++ +++R + G P E T
Sbjct: 14386 EPAVIPDVEIVEREMAPDFELDAELRRTLVV---RAGLSIRIFVPIKGR-----PAPEVT 14437
Query: 1587 -VPGSKSTATISGLKPGVDYTITVYAVTGRGD---------SPASSKPISINYRTEIDKP 1636
+ + + ++ +T+ + R D +PA K +N R +D P
Sbjct: 14438 WTKDNINLKNRANIENTESFTLLIIPECNRYDTGKFVMTIENPAGKKSGFVNVRV-LDTP 14496
Query: 1637 S---QMQVTDVQDNSISVKW----LPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMT 1689
++ TD+ +S+++ W + S +T Y V T T +
Sbjct: 14497 GPVLNLRPTDITKDSVTLHWDLPLIDGGSRITNYIVEKREATRKS-YSTATTKCHKCTYK 14555
Query: 1690 IEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDR----PKGLAFTDVDVDSIKIAWES 1745
+ GL EY V A+N G +P T P L D+ ++ +AW
Sbjct: 14556 VTGLSEGCEYFFRVMAENEYGIGEPTETTEPVKASEAPSPPDSLNIMDITKSTVSLAWPK 14615
Query: 1746 PQ----GQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHD--- 1798
P+ +++ Y + G E ++ L G EYT V+A++
Sbjct: 14616 PKHDGGSKITGYVIEAQRKGSDQWTHITTVKGLE--CVVRNLTEGEEYTFQVMAVNSAGR 14673
Query: 1799 --DMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPM 1856
ES+P+I + T +P Q + + + + G R + T K G
Sbjct: 14674 SAPRESRPVIVKEQTMLPELDLRGIYQKLVIAKAGDNIKVEIPVLG-RPKPTVTWKKGDQ 14732
Query: 1857 -----KEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVS----- 1906
+ +N ++S +++ + + + Y LT+R G V + +
Sbjct: 14733 ILKQTQRVNFETTATSTILN-INECVRSDSGPY----PLTARNIVGEVGDVITIQVHDIP 14787
Query: 1907 --PPRRARVTDATETTITISWRTKTE----TITGFQVDAVPANGQTPIQRTIKPDVRSYT 1960
P + + + +T SW I+ + V+ + T ++ +Y
Sbjct: 14788 GPPTGPIKFDEVSSDFVTFSWDPPENDGGVPISNYVVEMRQTDSTTWVELATTVIRTTYK 14847
Query: 1961 ITGLQPGTDYKIYL-----YTLNDNARSSPVVIDASTAIDAPSNL-RFLATTPNSLLVSW 2014
T L G +Y+ + Y + S+ +V + + P + A T +S+ +SW
Sbjct: 14848 ATRLTTGLEYQFRVKAQNRYGVGPGITSACIVANYPFKVPGPPGTPQVTAVTKDSMTISW 14907
Query: 2015 QPP----RARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNN 2070
P + I GY ++ ++ + V + +GL G Y VIA
Sbjct: 14908 HEPLSDGGSPILGYHVERKERNGILWQTVSKALVPGNIFKSSGLTDGIAYEFRVIAENMA 14967
Query: 2071 QKSEP 2075
KS+P
Sbjct: 14968 GKSKP 14972
Score = 116 bits (291), Expect = 2e-25
Identities = 288/1381 (20%), Positives = 498/1381 (36%), Gaps = 191/1381 (13%)
Query: 766 LDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDT 825
+D + TS I + G K + ++ G+ ++ P + V + D
Sbjct: 6673 IDTTAEQTSFRILEAKKGDKGRYKIVLQNKHGKAEGFINLKVIDVPGPVRNLEVTETFDG 6732
Query: 826 SIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETAN-SVTLSDLQPG-VQYNIT 879
+ + W P + I GY +V ++ + L + T++ LQ G V+Y
Sbjct: 6733 EVSLAWEEPLTDGGSKIIGY-VVERRDIKRKTWVLATDRAESCEFTVTGLQKGGVEYLFR 6791
Query: 880 IYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVT 935
+ A PV + D P ++ +V V++ W PPE + +T
Sbjct: 6792 VSARNRVGTGEPVETDNPVEARSKYDVPGPPLNVTITDVNRFGVSLTWEPPEYDGGAEIT 6851
Query: 936 GYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTT 995
Y +++ + + A VT + G Y F+V A + KP A
Sbjct: 6852 NYVIELRDKTSIRWDTAMTVRAEDLSATVTDVVEGQEYSFRVRAQNRIGVGKPSAATPFV 6911
Query: 996 KL-------DAPTNLQFVNETDSTVLVRWTPP----RAQITGYRLTVGLTRRGQPR---- 1040
K+ P NL ++T S+V ++W PP + I GY + G+
Sbjct: 6912 KVADPIERPSPPVNLTSSDQTQSSVQLKWEPPLKDGGSPILGY--IIERCEEGKDNWIRC 6969
Query: 1041 QYNVGPSVSKYPLRNLQPASE--YTVSLVAIKGNQESPKATGVFTT----LQPGSSIPPY 1094
+ P ++ Y + L+ ++ Y VS G + + G T ++P + +
Sbjct: 6970 NMKLVPELT-YKVTGLEKGNKYLYRVSAENKAGVSDPSEILGPLTADDAFVEPTMDLSAF 7028
Query: 1095 NTEV-----TETTIVI--TWTPAPRIGFKLGVRPSQGGEAPREVT-SDSGSIVVSGLTPG 1146
+ TI++ T P P + G + + G+ + T S +V+S
Sbjct: 7029 KDGLEVIVPNPITILVPSTGYPRPTATWCFGDKVLETGDRVKMKTLSAYAELVISPSERS 7088
Query: 1147 VEYVYTIQVLRDGQERDAPI-VNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPD--- 1202
+ +YT+++ + I VN + P +P + D+ LT WE PD
Sbjct: 7089 DKGIYTLKLENRVKTISGEIDVNVIARPSAPKELKFGDITKDSVHLT--WE---PPDDDG 7143
Query: 1203 ---ITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSV------------ 1247
+TGY + + + + + V T +L G EY V
Sbjct: 7144 GSPLTGYVVEKREVSRKTWTKVMDFV--TDLEFTVPDLVQGKEYLFKVCARNKCGPGEPA 7201
Query: 1248 YTVKDDKESVPISDTIIPEVPQLTDLSFVDITDSSIGLRWTPLNS---STIIGYRITVVA 1304
Y + S P + +P+ P+ ++ + D T +SI L W P + S I GY +
Sbjct: 7202 YVDEPVNMSTPAT---VPDPPE--NVKWRDRTANSIFLTWDPPKNDGGSRIKGYIVERCP 7256
Query: 1305 AGE------GIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQ--- 1355
G G P+ E ++ VTGLE G Y V L G S P+ T++
Sbjct: 7257 RGSDKWVACGEPVAETKME-------VTGLEEGKWYAYRVKALNRQGASKPSRPTEEIQA 7309
Query: 1356 --TAVPPPTDLRFTNIGPDTMR----------VTWAPPPSIDLTNFLVRYSPVKNEEDVA 1403
T P L + T++ VT P P I T + + ++
Sbjct: 7310 VDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWT----KADMILKQDKRI 7365
Query: 1404 ELSISPSDNAVVLTNLL---PGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDI 1460
+ P + V + + GT + +V+ + K G P D +D+
Sbjct: 7366 TIENVPKKSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNVLDKPG--PPAAFDITDV 7423
Query: 1461 TANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRNS------ITLTNLT 1510
T S + W PR + IT Y + R + V H +S T L
Sbjct: 7424 TNESCLLTWNPPRDDGGSKITNYVVER-------RATDSEVWHKLSSTVKDTNFKATKLI 7476
Query: 1511 PGTEYVVSIVALN------GREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAP-- 1562
P EY+ + A N + SP+ Q P LE T ++ ++W P
Sbjct: 7477 PNKEYIFRVAAENMYGVGEPVQASPITAKYQFDPPGPPTRLEPSDITKDAVTLTWCEPDD 7536
Query: 1563 --AVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYA--VTGRGDS 1618
+ Y + + + V+ +P +T + GL Y V A + G G
Sbjct: 7537 DGGSPITGYWVERLDPDTDKWVRCNKMPVKDTTYRVKGLTNKKKYRFRVLAENLAGPGKP 7596
Query: 1619 PASSKPISINYRTEID---KPSQMQVTDVQDNSISVKWL----PSSSPVTGYRVTTTPKN 1671
S++PI I + ID P + V DV S+ + W + + Y V K
Sbjct: 7597 SKSTEPILI--KDPIDPPWPPGKPTVKDVGKTSVRLNWTKPEHDGGAKIESY-VIEMLKT 7653
Query: 1672 GPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQP-------LVQTAVTNID 1724
G G T+ + GL EY V A N +GES+P L + +
Sbjct: 7654 GTDEWVRVAEGVPTTQHLLPGLMEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPS 7713
Query: 1725 RPKGLAFTDVDVDSIKIAWESPQ----GQVSRYRVTYSSPEDGIHELFPAPDG--EEDTA 1778
P+ L ++ ++ + W P+ ++ Y V D + + D ++
Sbjct: 7714 PPRWLEVINITKNTADLKWTVPEKDGGSPITNYIV---EKRDVRRKGWQTVDTTVKDTKC 7770
Query: 1779 ELQGLRPGSEYTVSVVAL-------HDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSA 1831
+ L GS Y V A + ++E L T P L VT +
Sbjct: 7771 TVTPLTEGSLYVFRVAAENAIGQSDYTEIEDSVLAKDTFTTPGPPYALAVVDVTKRHVDL 7830
Query: 1832 QWTPPNVQ--LTGYRVRVTPKEKTGP--MKEINLAPDSSSVVVSGLMVATKYEVSVYALK 1887
+W PP R + KE+ G +K A + V+ ++ T+ + V A
Sbjct: 7831 KWEPPKNDGGRPIQRYVIEKKERLGTRWVKAGKTAGPDCNFRVTDVIEGTEVQFQVRAEN 7890
Query: 1888 DTLTSRPAQGV-VTTLEN----VSPPRRARVTDATETTITISWRTKTET----ITGFQVD 1938
+ P++ + ++E+ SPP VTDA I I+W+ + I G+ V+
Sbjct: 7891 EAGVGHPSEPTEILSIEDPTSPPSPPLDLHVTDAGRKHIAIAWKPPEKNGGSPIIGYHVE 7950
Query: 1939 AVPANGQTPIQRTIKP--DVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDA 1996
P + ++ +P D++ G+ P +Y + + +N S P I +
Sbjct: 7951 MCPVGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAIGVSEPSEISENVVAKD 8010
Query: 1997 P 1997
P
Sbjct: 8011 P 8011
Score = 115 bits (287), Expect = 7e-25
Identities = 286/1430 (20%), Positives = 524/1430 (36%), Gaps = 172/1430 (12%)
Query: 785 KYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPT-VDQVDDTSIVVRWSRPQ----APIT 839
+Y++ + ++ G +S+ ++ P P P ++ + + W RPQ A I
Sbjct: 19487 QYVLTLKNVA--GTRSVAVNCKVLDKPGPPAGPLEINGLTAEKCSLSWGRPQEDGGADID 19544
Query: 840 GYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETT 899
Y + + + T S ++ L G +Y + V + P+ E+
Sbjct: 19545 YYIVEKRETSHLAWTICEGELQMTSCKVTKLLKGNEYIFRVTGVNKYGVGEPL----ESV 19600
Query: 900 GTPRSD--TVPSP-RDLQFVEVTDVKVTIMWTPPES----AVTGYRVDVIPVN-LPGEHG 951
D TVPSP L+ VT +T+ W+ PES ++GY ++ N L
Sbjct: 19601 AIKALDPFTVPSPPTSLEITSVTKESMTLCWSRPESDGGSEISGYIIERREKNSLRWVRV 19660
Query: 952 QRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNL-------Q 1004
+ P+ + + TGL G Y ++V+A + S P + + P L +
Sbjct: 19661 NKKPVY-DLRVKSTGLREGCEYEYRVYAENAAGLSLPSETSPLIRAEDPVFLPSPPSKPK 19719
Query: 1005 FVNETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPAS 1060
V+ +T+ + W P A ITGY + + + ++Y + L +
Sbjct: 19720 IVDSGKTTITIAWVKPLFDGGAPITGYTVEYKKSDDTDWKTSIQSLRGTEYTISGLTTGA 19779
Query: 1061 EYTVSLVAIK---GNQESPKATGVFTTLQPGSSIPPYNTEVTETTIV-----ITWT---- 1108
EY + ++ + S + + + ++E+ +T IV T T
Sbjct: 19780 EYVFRVKSVNKVGASDPSDSSDPQIAKEREEEPLFDIDSEMRKTLIVKAGASFTMTVPFR 19839
Query: 1109 --PAPRIGFKLGVRPSQG--GEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDA 1164
P P + L +P A + T S+ + YT+ +
Sbjct: 19840 GRPVPNV---LWSKPDTDLRTRAYVDTTDSRTSLTIENANRNDSGKYTLTIQNVLSAASL 19896
Query: 1165 PIVNKVVTPLSPPTNLHLE-ANPDTGVLTVSW---ERSTTPDITGYRITTTPTNGQQGNS 1220
+V KV+ PPTN+ ++ ++ VL SW E + Y I + + S
Sbjct: 19897 TLVVKVLDTPGPPTNITVQDVTKESAVL--SWDVPENDGGAPVKNYHIEKREASKKAWVS 19954
Query: 1221 LE--------EVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPEVPQLTD 1272
+ +V + + + + +S E+ V + + KE V I++ P P+
Sbjct: 19955 VTNNCNRLSYKVTNLQEGAIYYFRVSGENEFGVGIPA--ETKEGVKITEK--PSPPE--K 20008
Query: 1273 LSFVDITDSSIGLRWTPLN---SSTIIGYRITVVAAGEGIPIFEDFVDSSVG---YYTVT 1326
L I+ S+ L W S I+ Y + + G+ +++V +V ++ V+
Sbjct: 20009 LGVTSISKDSVSLTWLKPEHDGGSRIVHYVVEALEKGQ-----KNWVKCAVAKSTHHVVS 20063
Query: 1327 GLEPGIDYDISVITLINGGESAPT-----TLTQQTAVPPPTDLRFTNIGPDTMRVTWAPP 1381
GL +Y V G S P L ++ PP D++ N T+ V
Sbjct: 20064 GLRENSEYFFRVFAENQAGLSDPRELLLPVLIKEQLEPPEIDMK--NFPSHTVYVRAGSN 20121
Query: 1382 PSIDLTNFLVRYSPVKNEEDVAELSISPSDNA-VVLTNLLPGTEYVVSVSSVYEQHESTP 1440
+D+ V D L + N + NL + V+ + + +
Sbjct: 20122 LKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADAGRYEITAAN 20181
Query: 1441 LRGRQKTGLD--------SPTG-IDFSDITANSFTVHWIAPR----ATITGYRIRHHPEH 1487
G K ++ PTG + SDIT S T+ W P+ + +T Y + E
Sbjct: 20182 SSGTTKAFINIVVLDRPGPPTGPVVISDITEESVTLKWEPPKYDGGSQVTNYILLKR-ET 20240
Query: 1488 FSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGR------EESPLLIGQQSTVSDV 1541
+ E +R + + LT G EY I A N + + + + T
Sbjct: 20241 STAVWTEVSATVARTMMKVMKLTTGEEYQFRIKAENRFGISDHIDSACVTVKLPYTTPGP 20300
Query: 1542 PRDLEVVAATPTSLLISWDAPAVT----VRYYRITYGETGGNSPVQEFTVPGSKSTATIS 1597
P V T S+ + W P V Y + + + + + ++
Sbjct: 20301 PSTPWVTNVTRESITVGWHEPVSNGGSAVVGYHLEMKDRNSILWQKANKLVIRTTHFKVT 20360
Query: 1598 GLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKW---- 1653
+ G+ Y VYA G S + + P +++TD+ NS+S+ W
Sbjct: 20361 TISAGLIYEFRVYAENAAGVGKPSHPSEPVLAIDACEPPRNVRITDISKNSVSLSWQQPA 20420
Query: 1654 LPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE-S 1712
S +TGY V TK +T+ I GL +Y V+A+N G S
Sbjct: 20421 FDGGSKITGYIVERRDLPDGRWTKASFTNVTETQFIISGLTQNSQYEFRVFARNAVGSIS 20480
Query: 1713 QPL-VQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAP 1771
P V +T ID G D+ ++ ++ + G + R S E +
Sbjct: 20481 NPSEVVGPITCIDSYGGPVI-DLPLEYTEVV-KYRAGTSVKLRAGISGKPAPTIEWYK-D 20537
Query: 1772 DGEEDTAELQGLRPGSEYTVSVVALHDDMES-------QPLIGTQSTAI---------PA 1815
D E T L + ++ ++ D + S + +G+ S I P
Sbjct: 20538 DKELQTNALVCVENTTDLASILIKDADRLNSGCYELKLRNAMGSASATIRVQILDKPGPP 20597
Query: 1816 PTDLKFTQVTPTSLSAQWTPP----NVQLTGYRVRVTPKEKTGPM--KEINLAPDSSSVV 1869
++F VT ++ W PP ++T Y + K +T + ++ + +
Sbjct: 20598 GGPIEFKTVTAEKITLLWRPPADDGGAKITHY---IVEKRETSRVVWSMVSEHLEECIIT 20654
Query: 1870 VSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENV----SPPRRARVTDATETTITISW 1925
+ ++ +Y V A+ P + +N PP VT T+ ++T+ W
Sbjct: 20655 TTKIIKGNEYIFRVRAVNKYGIGEPLESDSVVAKNAFVTPGPPGIPEVTKITKNSMTVVW 20714
Query: 1926 RTKT----ETITGFQV---DAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLN 1978
I+G+ + D ++ TI+ D R +TGL +DY+ + +N
Sbjct: 20715 SRPIADGGSDISGYFLEKRDKKSLGWFKVLKETIR-DTRQ-KVTGLTENSDYQYRVCAVN 20772
Query: 1979 DNAR---SSPVVI-DASTAIDAP---SNLRFLATTPNSLLVSWQPP----RARITGYIIK 2027
+ S P A+ ID P + +R +T +S+ + W P + +TGY+++
Sbjct: 20773 AAGQGPFSEPSEFYKAADPIDPPGPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVVE 20832
Query: 2028 YEKPGSPPREVVP-RPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPL 2076
+ V + TE ++ L+PG Y V A+ + EP+
Sbjct: 20833 IRQGEEEEWTTVSTKGEVRTTEYVVSNLKPGVNYYFRVSAVNCAGQGEPI 20882
Score = 114 bits (286), Expect = 9e-25
Identities = 308/1475 (20%), Positives = 520/1475 (35%), Gaps = 204/1475 (13%)
Query: 806 SQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ----APITGYRIVYSPSVEGS-STELNLPE 860
S+ P P + T+ V+ + + W P+ A IT Y I T + +
Sbjct: 6814 SKYDVPGPPLNVTITDVNRFGVSLTWEPPEYDGGAEITNYVIELRDKTSIRWDTAMTVRA 6873
Query: 861 TANSVTLSDLQPGVQYNITIYA-----VEENQESTPVVIQQETTGTPRSDTVPSPRDLQF 915
S T++D+ G +Y+ + A V + +TP V + P P +L
Sbjct: 6874 EDLSATVTDVVEGQEYSFRVRAQNRIGVGKPSAATPFVKVADPIERPSP-----PVNLTS 6928
Query: 916 VEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGV 971
+ T V + W PP S + GY ++ + + +VTGL G
Sbjct: 6929 SDQTQSSVQLKWEPPLKDGGSPILGYIIERCEEGKDNWIRCNMKLVPELTYKVTGLEKGN 6988
Query: 972 TYYFKVFAVSHGRESKP------LTA-----QQTTKLDA-PTNLQFVNETDSTVLVRWTP 1019
Y ++V A + S P LTA + T L A L+ + T+LV T
Sbjct: 6989 KYLYRVSAENKAGVSDPSEILGPLTADDAFVEPTMDLSAFKDGLEVIVPNPITILVPSTG 7048
Query: 1020 -PRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKA 1078
PR T L + + ++S Y + P+ + +K
Sbjct: 7049 YPRPTATWCFGDKVLETGDRVKM----KTLSAYAELVISPSERSDKGIYTLKLENRVKTI 7104
Query: 1079 TG---VFTTLQPGSSIPPYNTEVTETTIVITWTP------APRIGFKLGVRPSQGGEAPR 1129
+G V +P + ++T+ ++ +TW P +P G+ + R E R
Sbjct: 7105 SGEIDVNVIARPSAPKELKFGDITKDSVHLTWEPPDDDGGSPLTGYVVEKR-----EVSR 7159
Query: 1130 EVTSDSGSIV------VSGLTPGVEYVYTIQVLRDGQERDAPIVNKVV---TPLS---PP 1177
+ + V V L G EY++ + + V++ V TP + PP
Sbjct: 7160 KTWTKVMDFVTDLEFTVPDLVQGKEYLFKVCARNKCGPGEPAYVDEPVNMSTPATVPDPP 7219
Query: 1178 TNLHLEANPDTGVLTVSWERSTTPD---ITGYRITTTPTNGQQGNSLEEVVHADQSSCTF 1234
N+ + ++W+ I GY + P + + E V + T
Sbjct: 7220 ENVKWRDRTANSIF-LTWDPPKNDGGSRIKGYIVERCPRGSDKWVACGEPVAETKMEVT- 7277
Query: 1235 DNLSPGLEYNVSVYTVKDDKESVPISDT-------------IIPEVPQLTDLSF-----V 1276
L G Y V + S P T I +V L L+ +
Sbjct: 7278 -GLEEGKWYAYRVKALNRQGASKPSRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKI 7336
Query: 1277 DITDSSIG-----LRWTPLNSSTIIGYRITVVAAGEGIP-----IFEDFVDSSVGYYTVT 1326
++ + G + WT + RIT+ E +P D S G Y +
Sbjct: 7337 ELPATVTGKPEPKITWTKADMILKQDKRITI----ENVPKKSTVTIVDSKRSDTGTYIIE 7392
Query: 1327 GLEPGIDYDISVITLINGGESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAPPPS--- 1383
+ + G +A + PP T++ ++ +TW PP
Sbjct: 7393 AVN------------VCGRATAVVEVNVLDKPGPPAAFDITDVTNESCLLTWNPPRDDGG 7440
Query: 1384 IDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSS-----VYEQHES 1438
+TN++V +E +LS + D T L+P EY+ V++ V E ++
Sbjct: 7441 SKITNYVVERRATDSEV-WHKLSSTVKDTNFKATKLIPNKEYIFRVAAENMYGVGEPVQA 7499
Query: 1439 TPLRGR-QKTGLDSPTGIDFSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPR 1493
+P+ + Q PT ++ SDIT ++ T+ W P + ITGY + R
Sbjct: 7500 SPITAKYQFDPPGPPTRLEPSDITKDAVTLTWCEPDDDGGSPITGYWVERLDPDTDKWVR 7559
Query: 1494 EDRVPHSRNSITLTNLTPGTEYVVSIVALN-------GREESPLLIGQQSTVSDVPRDLE 1546
+++P + + LT +Y ++A N + P+LI P
Sbjct: 7560 CNKMPVKDTTYRVKGLTNKKKYRFRVLAENLAGPGKPSKSTEPILIKDPIDPPWPPGKPT 7619
Query: 1547 VVAATPTSLLISWDAP----AVTVRYYRITYGETGGNSPVQEFTVPGSKSTA-TISGLKP 1601
V TS+ ++W P + Y I +TG + V+ G +T + GL
Sbjct: 7620 VKDVGKTSVRLNWTKPEHDGGAKIESYVIEMLKTGTDEWVR--VAEGVPTTQHLLPGLME 7677
Query: 1602 GVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQ---MQVTDVQDNSISVKWL---- 1654
G +Y+ V AV G+S S + R ++ PS ++V ++ N+ +KW
Sbjct: 7678 GQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLEVINITKNTADLKWTVPEK 7737
Query: 1655 PSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQ- 1713
SP+T Y V G T D T+ T+ L YV V A+N G+S
Sbjct: 7738 DGGSPITNYIVEKRDVRRKGWQTVDTTVKD-TKCTVTPLTEGSLYVFRVAAENAIGQSDY 7796
Query: 1714 ------PLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQ----VSRYRVTYSSPEDG 1763
L + T P LA DV + + WE P+ + RY +
Sbjct: 7797 TEIEDSVLAKDTFTTPGPPYALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKERLGT 7856
Query: 1764 IHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPT------ 1817
G + + + G+E V A ++ P T+ +I PT
Sbjct: 7857 RWVKAGKTAGPDCNFRVTDVIEGTEVQFQVRAENEAGVGHPSEPTEILSIEDPTSPPSPP 7916
Query: 1818 -DLKFTQVTPTSLSAQWTPPNVQ----LTGYRVRVTPKEKTGPMKEINLAP--DSSSVVV 1870
DL T ++ W PP + GY V + P T +N P D V
Sbjct: 7917 LDLHVTDAGRKHIAIAWKPPEKNGGSPIIGYHVEMCP-VGTEKWMRVNSRPIKDLKFKVE 7975
Query: 1871 SGLMVATKYEVSVYALKDTLTSRP---AQGVVTTLENVSP-----PRRARVTDATETTIT 1922
G++ +Y + V A+ S P ++ VV + P V + + +I
Sbjct: 7976 EGVVPDKEYVLRVRAVNAIGVSEPSEISENVVAKDPDCKPTIDLETHDIIVIEGEKLSIP 8035
Query: 1923 ISWRTKTETITGFQVDAVPANGQTPIQRTIKPD-VRSYTITGLQPGTDYKIYLYTLNDNA 1981
+ +R + D + T+K D + ++ D IY TL +
Sbjct: 8036 VPFRAVPVPTVSWHKDGKEVKASDRL--TMKNDHISAHLEVPKSVRADAGIYTITLENKL 8093
Query: 1982 RSSPVVIDAST-AIDAP-SNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPP 2035
S+ I+ + P +++ T +S ++W+PP I Y+++ + G
Sbjct: 8094 GSATASINVKVIGLPGPCKDIKASDITKSSCKLTWEPPEFDGGTPILHYVLERREAGR-- 8151
Query: 2036 REVVP-RPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELPQLVTLPHP 2094
R +P T+ L P EY V A+ +G + EL V P
Sbjct: 8152 RTYIPVMSGENKLSWTVKDLIPNGEYFFRVKAVNK-------VGGGEYIELKNPVIAQDP 8204
Query: 2095 NLHGPEILDV----PSTVQKTPFVTHPGYDTGNGI 2125
+DV P+ T P YD G+ I
Sbjct: 8205 KQPPDPPVDVEVHNPTAEAMTITWKPPLYDGGSKI 8239
Score = 114 bits (286), Expect = 9e-25
Identities = 280/1356 (20%), Positives = 495/1356 (36%), Gaps = 217/1356 (16%)
Query: 727 SVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQ--YLDLPSTA--TSVNIPDLLP 782
+VTE+T+ V+SW D G ++++ + ++ + + + ++ S T + + LL
Sbjct: 15191 AVTEVTSEKCVLSWFPPLDD-GGAKIDHYIVQKRETSRLAWTNVASEVQVTKLKVTKLLK 15249
Query: 783 GRKYI-----VNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAP 837
G +YI VN Y + E E +L+ + PD P +P V + S+VV W P +
Sbjct: 15250 GNEYIFRVMAVNKYGVGEPLESEPVLAVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDS- 15308
Query: 838 ITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQ-------PGVQYNITIYAVEENQEST 890
G + + VE N TL+DL+ G +Y I A S
Sbjct: 15309 -DGGSEIINYIVERRDKAGQRWIKCNKKTLTDLRYKVSGLTEGHEYEFRIMAENAAGISA 15367
Query: 891 PVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNL 946
P P + + ++ + ++I W P S +TGY V++ L
Sbjct: 15368 PSPTSPFYKACDTVFKPGPPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIA---L 15424
Query: 947 PGEHGQRLPIS----RNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLD---A 999
P E ++ + T +TGL+ Y +++A++ +P T K +
Sbjct: 15425 PEEDEWQIVTPPAGLKATSYTITGLTENQEYKIRIYAMNSEGLGEPALVPGTPKAEDRML 15484
Query: 1000 PTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPR---QYNVGPSVSKYPLRNL 1056
P ++ + V +R RL V + R P + G S+ K ++
Sbjct: 15485 PPEIELDADLRKVVTIR------ACCTLRLFVPIKGRPAPEVKWARDHGESLDK---ASI 15535
Query: 1057 QPASEYTVSLVAIKGNQESPK----------ATGVFTTLQ----PGSSIPPYNTEVTETT 1102
+ S YT+ +V +S K + F ++ PG EVT+T+
Sbjct: 15536 ESTSSYTLLIVGNVNRFDSGKYILTVENSSGSKSAFVNVRVLDTPGPPQDLKVKEVTKTS 15595
Query: 1103 IVITWTPAPRI--GFKLGVRPSQGGEAPREVTS------DSGSIVVSGLTPGVEYVYTIQ 1154
+ +TW P P + G K+ + E+ R+ S S V L G Y + +
Sbjct: 15596 VTLTWDP-PLLDGGSKIKNYIVEKRESTRKAYSTVATNCHKTSWKVDQLQEGCSYYF--R 15652
Query: 1155 VLRDGQ------ERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPD---ITG 1205
VL + + A V PL P ++ ++ +++SWE+ I G
Sbjct: 15653 VLAENEYGIGLPAETAESVKASERPLPPGKITLMDVTRNS--VSLSWEKPEHDGGSRILG 15710
Query: 1206 YRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYT-----VKDDKE-SVPI 1259
Y I T G + V +++ T L G EY+ V + D ++ SVP+
Sbjct: 15711 Y-IVEMQTKGSDKWATCATVKVTEATIT--GLIQGEEYSFRVSAQNEKGISDPRQLSVPV 15767
Query: 1260 --SDTIIPEVPQLTDLSFVDITDSSI------------GLRW----TPLNSSTIIGYRIT 1301
D +IP +L +F + + + W PL +T + T
Sbjct: 15768 IAKDLVIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAEST 15827
Query: 1302 VVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTL---TQQTAV 1358
+ +D VG+Y V+ L N A TL
Sbjct: 15828 ---ENNSLLTIKDACREDVGHY--------------VVKLTNSAGEAIETLNVIVLDKPG 15870
Query: 1359 PPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAE---LSISPSDNAVV 1415
PP ++ + D++ ++W PP D + + Y K + +S + + +
Sbjct: 15871 PPTGPVKMDEVTADSITLSWG-PPKYDGGSSINNYIVEKRDTSTTTWQIVSATVARTTIK 15929
Query: 1416 LTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTG-----LDSPTGIDFSDITA-NSFTVHW 1469
L G EY +++ +ST L + P G +++ +S V W
Sbjct: 15930 ACRLKTGCEYQFRIAAENRYGKSTYLNSEPTVAQYPFKVPGPPGTPVVTLSSRDSMEVQW 15989
Query: 1470 IAP----RATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGR 1525
P + + GY + + + ++ P + T L G EY + A
Sbjct: 15990 NEPISDGGSRVIGYHLERKERNSILWVKLNKTPIPQTKFKTTGLEEGVEYEFRVSA---- 16045
Query: 1526 EESPLLIGQQSTVSD--VPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQ 1583
E+ + IG+ S VS+ V RD P +++++ + +VT+++ + TY G S +
Sbjct: 16046 -ENIVGIGKPSKVSECYVARDPCDPPGRPEAIIVTRN--SVTLQWKKPTY---DGGSKIT 16099
Query: 1584 EFTVPGS--------KSTAT--------ISGLKPGVDYTITVYAVTGRG-DSPASSKPIS 1626
+ V K++ T ++GL Y V A G S S +
Sbjct: 16100 GYIVEKKELPEGRWMKASFTNIIDTHFEVTGLVEDHRYEFRVIARNAAGVFSEPSESTGA 16159
Query: 1627 INYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQT 1686
I R E+D P +D + ++V P PT G +
Sbjct: 16160 ITARDEVDPPRISMDPKYKDTIV-------VHAGESFKVDADIYGKPIPTIQWIKGDQEL 16212
Query: 1687 EMTIEGLQPTVEYVVS---------------VYAQNPSGESQPLVQTAVTNIDRP----K 1727
T + ++ S + A+N +GE V V +DRP
Sbjct: 16213 SNTARLEIKSTDFATSLSVKDAVRVDSGNYILKAKNVAGERSVTVNVKV--LDRPGPPEG 16270
Query: 1728 GLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHEL-FPAPDGEEDT--AELQGLR 1784
+ + V + +AW+ P + Y L + D T ++ L
Sbjct: 16271 PVVISGVTAEKCTLAWKPPLQDGGSDIINYIVERRETSRLVWTVVDANVQTLSCKVTKLL 16330
Query: 1785 PGSEYTVSVVALH-----DDMESQPLIGTQSTAIP-APTDLKFTQVTPTSLSAQWTPP-- 1836
G+EYT ++A++ + +ES+P++ +P AP + T VT S+ W P
Sbjct: 16331 EGNEYTFRIMAVNKYGVGEPLESEPVVAKNPFVVPDAPKAPEVTTVTKDSMIVVWERPAS 16390
Query: 1837 --NVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRP 1894
++ GY + KE + + V+GL+ YE V A S P
Sbjct: 16391 DGGSEILGYVLEKRDKEGIRWTRCHKRLIGELRLRVTGLIENHDYEFRVSAENAAGLSEP 16450
Query: 1895 A-----QGVVTTLENVSPPRRARVTDATETTITISW 1925
+ Q + PP +V D T +++ +SW
Sbjct: 16451 SPPSAYQKACDPIYKPGPPNNPKVIDITRSSVFLSW 16486
Score = 114 bits (284), Expect = 2e-24
Identities = 358/1658 (21%), Positives = 597/1658 (36%), Gaps = 251/1658 (15%)
Query: 607 SSSGPVEVFIT----ETPSQPNSHPIQWNAPQPSHISKYILRWRP---------KNSVGR 653
+SSG F+T +TP P + ++ + L W P KN V
Sbjct: 17727 NSSGSKSAFVTVKVLDTPGPPQNLAVKEVRKDSA-----FLVWEPPIIDGGAKVKNYVID 17781
Query: 654 WKEATIPGHLN--------SYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTP 705
+E+T + N S+ ++ L G +Y ++++ ++G P
Sbjct: 17782 KRESTRKAYANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFG-------------VGVP 17828
Query: 706 VTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVS----ASDTVSGFRVEYELSEEGD 761
V + P SP ++T+++ +S + W V G+ VE + +G
Sbjct: 17829 VETVDAVKAAEPPSP--PGKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVE--MQPKGT 17884
Query: 762 EPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQ 821
E + S + + L G++Y V +E G+ + A D P++
Sbjct: 17885 EKWSIVAESKVCNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKL 17944
Query: 822 VDDTSIVVRWS--RPQAPITGY-RIVYSPSVEGS----STELNLPETANSVTLSDLQPGV 874
+T + + + P+ G R S +G +T +N+ ETA S L ++ G
Sbjct: 17945 PFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLH-IKEGN 18003
Query: 875 QYNITIYAVEENQESTPV-----VIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTP 929
+ + Y V + VI E G P ++F EV+ V I W P
Sbjct: 18004 KDDFGKYTVTATNSAGTATENLSVIVLEKPGPPVGP-------VRFDEVSADFVVISWEP 18056
Query: 930 PESA----VTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRE 985
P ++ Y V+ H ++R T ++T L G Y F++FA + +
Sbjct: 18057 PAYTGGCQISNYIVEKRDTTTTTWHMVSATVARTTI-KITKLKTGTEYQFRIFAENRYGK 18115
Query: 986 SKPLTA-----QQTTKLDAPTNLQFVNE-TDSTVLVRWTPP----RAQITGYRLTVGLTR 1035
S PL + Q K P FV + +LV+W P +I GY L
Sbjct: 18116 SAPLDSKAVIVQYPFKEPGPPGTPFVTSISKDQMLVQWHEPVNDGGTKIIGYHLEQKEKN 18175
Query: 1036 RGQPRQYNVGP-SVSKYPLRNLQPASEY--TVSLVAIKGNQESPKATGVFTTLQPGSSIP 1092
+ N P +K+ L EY VS I G + K + F P P
Sbjct: 18176 SILWVKLNKTPIQDTKFKTTGLDEGLEYEFKVSAENIVGIGKPSKVSECFVARDPCD--P 18233
Query: 1093 PYNTE---VTETTIVITW-TPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVE 1148
P E +T + + W PA G K+ G + G + + T +E
Sbjct: 18234 PGRPEAIVITRNNVTLKWKKPAYDGGSKI------TGYIVEKKDLPDGRWMKASFTNVLE 18287
Query: 1149 YVYTIQVLRDGQERDAPIV-NKVVTPLSPPT---------------NLHLEAN-PDTGVL 1191
+T+ L + Q + ++ S P+ N L+ D V+
Sbjct: 18288 TEFTVSGLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARDEIDAPNASLDPKYKDVIVV 18347
Query: 1192 TVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNL---------SPGLE 1242
DI G I + + G LEE + T + G +
Sbjct: 18348 HAGETFVLEADIRGKPIPDVVWS-KDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQ 18406
Query: 1243 YNVSVYTVKDDKESVPISDTIIPEV-PQLTDLSFVDITDSSIGLRWTP--LNSSTIIGYR 1299
Y + + V K S+PI+ ++ P L +T L W P + I +
Sbjct: 18407 YILKLSNVGGTK-SIPITVKVLDRPGPPEGPLKVTGVTAEKCYLAWNPPLQDGGANISHY 18465
Query: 1300 ITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGG-----ESAPTTLTQ 1354
I + + + Y VT L PG +Y V+ + G ES P T
Sbjct: 18466 IIEKRETSRLSWTQVSTEVQALNYKVTKLLPGNEYIFRVMAVNKYGIGEPLESGPVTACN 18525
Query: 1355 QTAVP-PPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISP---S 1410
P PP+ + I D+M VTWA P T +++E V + +
Sbjct: 18526 PYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDKEGVRWTKCNKKTLT 18585
Query: 1411 DNAVVLTNLLPGTEYVVSVSS-----VYEQHESTPLRGRQKTGL---DSPTGIDFSDITA 1462
D + +T L G Y V++ V E E + R L P+ +D +
Sbjct: 18586 DLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFY-RACDALYPPGPPSNPKVTDTSR 18644
Query: 1463 NSFTVHWIAP----RATITGYRIRHHPEHFSGRPREDRVPHS---RNSITLTNLTPGTEY 1515
+S ++ W P A + GY + + + P + T+T L TEY
Sbjct: 18645 SSVSLAWSKPIYDGGAPVKGYVV--EVKEAAADEWTTCTPPTGLQGKQFTVTKLKENTEY 18702
Query: 1516 VVSIVALN--GREESPLLIGQQSTVSDV-PRDLEVVAATPTSLLISWDAPAVTVRYYRIT 1572
I A+N G E L G + P ++E+ A +++ A T+R +
Sbjct: 18703 NFRICAINSEGVGEPATLPGSVVAQERIEPPEIELDADLRKVVVLRASA---TLRLFVTI 18759
Query: 1573 YGETGGNSPVQEFTVPGSKSTAT-ISGLKPGVDYTITVYAVTGRGDS---------PASS 1622
G P E ++ T + ++ +T+ V R DS + S
Sbjct: 18760 KGR-----PEPEVKWEKAEGILTDRAQIEVTSSFTMLVIDNVTRFDSGRYNLTLENNSGS 18814
Query: 1623 KPISINYRTEIDKPS---QMQVTDVQDNSISVKWLP----SSSPVTGYRV---TTTPKNG 1672
K +N R +D PS + + +V+ +S+++ W P + +T Y V TT K
Sbjct: 18815 KTAFVNVRV-LDSPSAPVNLTIREVKKDSVTLSWEPPLIDGGAKITNYIVEKRETTRK-- 18871
Query: 1673 PGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPK----G 1728
T T +T IE LQ Y V A N G P T + P
Sbjct: 18872 --AYATITNNCTKTTFRIENLQEGCSYYFRVLASNEYGIGLPAETTEPVKVSEPPLPPGR 18929
Query: 1729 LAFTDVDVDSIKIAWESPQ----GQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLR 1784
+ DV ++ I WE P+ +++ Y V + G + + A + GL
Sbjct: 18930 VTLVDVTRNTATIKWEKPESDGGSKITGYVVEMQT--KGSEKWSTCTQVKTLEATISGLT 18987
Query: 1785 PGSEYTVSVVALHDDMESQPL-----IGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQ 1839
G EY V A+++ S P + + I +L F T + + +V
Sbjct: 18988 AGEEYVFRVAAVNEKGRSDPRQLGVPVIARDIEIKPSVELPFH--TFNVKAREQLKIDVP 19045
Query: 1840 LTGYRVRVTPKEKTG-PMKEINLAPDSSSVVVSGLMV--ATKYEVSVYAL--KDTLTSRP 1894
G K G +KE SSS V+ L + A+K +V Y L ++ S
Sbjct: 19046 FKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSNSAGSIT 19105
Query: 1895 AQGVVTTLENVSPPRRARVTDATETTITISWRTKTE----TITGFQVDAVPANGQT---- 1946
+ L+ PP R+ + + +ITISW I+ + V+ T
Sbjct: 19106 VPITIIVLDRPGPPGPIRIDEVSCDSITISWNPPEYDGGCQISNYIVEKKETTSTTWHIV 19165
Query: 1947 --PIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDA-------- 1996
+ RT S I L G++Y+ + N +SS S+A+ A
Sbjct: 19166 SQAVART------SIKIVRLTTGSEYQFRVCAENRYGKSS---YSESSAVVAEYPFSPPG 19216
Query: 1997 -PSNLRFLATTPNSLLVSWQPP----RARITGYIIKYEKPGSPPREVVPRPRPGVTEATI 2051
P + + T +++LV+WQ P +R+ GY ++Y++ S + T+ +
Sbjct: 19217 PPGTPKVVHATKSTMLVTWQVPVNDGGSRVIGYHLEYKERSSILWSKANKILIADTQMKV 19276
Query: 2052 TGLEPGT--EYTIYVIAL----KNNQKSEPLIGRKKTD 2083
+GL+ G EY +Y + K ++ EP+ R D
Sbjct: 19277 SGLDEGLMYEYRVYAENIAGIGKCSKSCEPVPARDPCD 19314
Score = 111 bits (278), Expect = 8e-24
Identities = 306/1510 (20%), Positives = 522/1510 (34%), Gaps = 241/1510 (15%)
Query: 758 EEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLI---LSTSQTTAPDAP 814
E GD + L + A V + P + +Y + + I + + P AP
Sbjct: 7064 ETGDRVKMKTLSAYAELV----ISPSERSDKGIYTLKLENRVKTISGEIDVNVIARPSAP 7119
Query: 815 PDPTVDQVDDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTLSDL 870
+ + S+ + W P +P+TGY + + T++ T T+ DL
Sbjct: 7120 KELKFGDITKDSVHLTWEPPDDDGGSPLTGYVVEKREVSRKTWTKVMDFVTDLEFTVPDL 7179
Query: 871 QPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP 930
G +Y + A + P + + + + P ++++ + T + + W PP
Sbjct: 7180 VQGKEYLFKVCARNKCGPGEPAYVDEPVNMSTPATVPDPPENVKWRDRTANSIFLTWDPP 7239
Query: 931 E----SAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRES 986
+ S + GY V+ P P++ T EVTGL G Y ++V A++ S
Sbjct: 7240 KNDGGSRIKGYIVERCPRGSDKWVACGEPVA-ETKMEVTGLEEGKWYAYRVKALNRQGAS 7298
Query: 987 KP---------------------------LTAQQTTKLDAPTNLQFVNETDSTVLVRWTP 1019
KP LT + TK++ P + E T WT
Sbjct: 7299 KPSRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKIT----WT- 7353
Query: 1020 PRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKAT 1079
+A + + +T P++ V SK Y + V + G +
Sbjct: 7354 -KADMI-LKQDKRITIENVPKKSTVTIVDSK-----RSDTGTYIIEAVNVCGRATAVVEV 7406
Query: 1080 GVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRI--GFKLGVRPSQGGEAPREVTSDSGS 1137
V +PG T+VT + ++TW P PR G K+ + EV S
Sbjct: 7407 NVLD--KPGPPAAFDITDVTNESCLLTWNP-PRDDGGSKITNYVVERRATDSEVWHKLSS 7463
Query: 1138 IV------VSGLTPGVEYVYTI---QVLRDGQERDA-PIVNKV-VTPLSPPTNLHLEANP 1186
V + L P EY++ + + G+ A PI K P PPT L ++
Sbjct: 7464 TVKDTNFKATKLIPNKEYIFRVAAENMYGVGEPVQASPITAKYQFDPPGPPTRLE-PSDI 7522
Query: 1187 DTGVLTVSW---ERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEY 1243
+T++W + ITGY + + + ++ D ++ L+ +Y
Sbjct: 7523 TKDAVTLTWCEPDDDGGSPITGYWVERLDPDTDKWVRCNKMPVKD-TTYRVKGLTNKKKY 7581
Query: 1244 NVSVYTV------KDDKESVP--ISDTIIPEVPQLTDLSFVDITDSSIGLRWTPL---NS 1292
V K K + P I D I P P + D+ +S+ L WT
Sbjct: 7582 RFRVLAENLAGPGKPSKSTEPILIKDPIDPPWPP-GKPTVKDVGKTSVRLNWTKPEHDGG 7640
Query: 1293 STIIGYRITVVAAG--------EGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLING 1344
+ I Y I ++ G EG+P + + + GL G +Y V +
Sbjct: 7641 AKIESYVIEMLKTGTDEWVRVAEGVPTTQ---------HLLPGLMEGQEYSFRVRAVNKA 7691
Query: 1345 GESAPT-----TLTQQTAVP--PPTDLRFTNIGPDTMRVTWAPPP---SIDLTNFLVRYS 1394
GES P+ L ++ P PP L NI +T + W P +TN++V
Sbjct: 7692 GESEPSEPSDPVLCREKLYPPSPPRWLEVINITKNTADLKWTVPEKDGGSPITNYIVEKR 7751
Query: 1395 PVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVS-------SVYEQHESTPLRGRQKT 1447
V+ + + + D +T L G+ YV V+ S Y + E + L T
Sbjct: 7752 DVR-RKGWQTVDTTVKDTKCTVTPLTEGSLYVFRVAAENAIGQSDYTEIEDSVLAKDTFT 7810
Query: 1448 GLDSPTGIDFSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRNS 1503
P + D+T + W P+ I Y I + + + +
Sbjct: 7811 TPGPPYALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKERLGTRWVKAGKTAGPDCN 7870
Query: 1504 ITLTNLTPGTEYVVSIVALN----GREESP---LLIGQQSTVSDVPRDLEVVAATPTSLL 1556
+T++ GTE + A N G P L I ++ P DL V A +
Sbjct: 7871 FRVTDVIEGTEVQFQVRAENEAGVGHPSEPTEILSIEDPTSPPSPPLDLHVTDAGRKHIA 7930
Query: 1557 ISWDAPAVTVRYYRITYGETGGNSPVQEFTVP----GSKSTATIS-------------GL 1599
I+W P E G SP+ + V G++ ++ G+
Sbjct: 7931 IAWKPP------------EKNGGSPIIGYHVEMCPVGTEKWMRVNSRPIKDLKFKVEEGV 7978
Query: 1600 KPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSP 1659
P +Y + V AV G S+P I+ P D++ + I V S
Sbjct: 7979 VPDKEYVLRVRAVNAIG----VSEPSEISENVVAKDPDCKPTIDLETHDIIVIEGEKLSI 8034
Query: 1660 VTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYA---------QNPSG 1710
+R P + D+ M + + +E SV A +N G
Sbjct: 8035 PVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLG 8094
Query: 1711 ESQPLVQTAVTNIDRP-KGLAFTDVDVDSIKIAWESPQ--GQVSRYRVTYSSPEDGIHEL 1767
+ + V + P K + +D+ S K+ WE P+ G E G
Sbjct: 8095 SATASINVKVIGLPGPCKDIKASDITKSSCKLTWEPPEFDGGTPILHYVLERREAGRRTY 8154
Query: 1768 FPAPDGEEDTA-ELQGLRPGSEYTVSVVALH-----DDME-SQPLIGTQSTAIP-APTDL 1819
P GE + ++ L P EY V A++ + +E P+I P P D+
Sbjct: 8155 IPVMSGENKLSWTVKDLIPNGEYFFRVKAVNKVGGGEYIELKNPVIAQDPKQPPDPPVDV 8214
Query: 1820 KFTQVTPTSLSAQWTPP----NVQLTGYRV-RVTPKEKTGPMKEINLAPDSSSVVVSGLM 1874
+ T +++ W PP ++ GY + ++ E+ +L P + GL
Sbjct: 8215 EVHNPTAEAMTITWKPPLYDGGSKIMGYIIEKIAKGEERWKRCNEHLVP-ILTYTAKGLE 8273
Query: 1875 VATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTI------------- 1921
+Y+ V A S P++ T + V P +V T +
Sbjct: 8274 EGKEYQFRVRAENAAGISEPSRATPPT-KAVDPIDAPKVILRTSLEVKRGDEIALDASIS 8332
Query: 1922 -----TISWRTKTETITGFQVD--------------------AVPANGQTPIQRTIKPDV 1956
TI+W I ++ +P + I + K +
Sbjct: 8333 GSPYPTITWIKDENVIVPEEIKKRAAPLVRRRKGEVQEEEPFVLPLTQRLSIDNSKKGES 8392
Query: 1957 RSYTITGLQPGTDYKIYLYTL-NDNA-RSSPVVIDASTAIDAPSNLRFLATTPNSLLVSW 2014
+ L+P D+ +Y+ + ND+ +P + P N F S+L W
Sbjct: 8393 QLRVRDSLRP--DHGLYMIKVENDHGIAKAPCTVSVLDTPGPPINFVFEDIRKTSVLCKW 8450
Query: 2015 QPP----RARITGYIIKYEKPGSPPRE-VVPRPRPGVTEATITGLEPGTEYTIYVIALKN 2069
+PP + I Y ++ + P E +V + ++T L G EY V A
Sbjct: 8451 EPPLDDGGSEIINYTLEKKDKTKPDSEWIVVTSTLRHCKYSVTKLIEGKEYLFRVRAENR 8510
Query: 2070 NQKSEPLIGR 2079
P + +
Sbjct: 8511 FGPGPPCVSK 8520
Score = 109 bits (273), Expect = 3e-23
Identities = 290/1404 (20%), Positives = 524/1404 (37%), Gaps = 190/1404 (13%)
Query: 812 DAPPDPT----VDQVDDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETAN 863
D P PT + + + S+ ++W P+ + +T Y ++ + TE++
Sbjct: 20196 DRPGPPTGPVVISDITEESVTLKWEPPKYDGGSQVTNYILLKRETSTAVWTEVSATVART 20255
Query: 864 SVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFV-EVTDVK 922
+ + L G +Y I A EN+ I T P P +V VT
Sbjct: 20256 MMKVMKLTTGEEYQFRIKA--ENRFGISDHIDSACVTVKLPYTTPGPPSTPWVTNVTRES 20313
Query: 923 VTIMWTPPES----AVTGYRVDVIPVN-LPGEHGQRLPISRNTFAEVTGLSPGVTYYFKV 977
+T+ W P S AV GY +++ N + + +L I R T +VT +S G+ Y F+V
Sbjct: 20314 ITVGWHEPVSNGGSAVVGYHLEMKDRNSILWQKANKLVI-RTTHFKVTTISAGLIYEFRV 20372
Query: 978 FAVSHGRESKPL-TAQQTTKLDA---PTNLQFVNETDSTVLVRWTPPR----AQITGYRL 1029
+A + KP ++ +DA P N++ + + ++V + W P ++ITGY
Sbjct: 20373 YAENAAGVGKPSHPSEPVLAIDACEPPRNVRITDISKNSVSLSWQQPAFDGGSKITGYI- 20431
Query: 1030 TVGLTRRGQP-----RQYNVGPSVSKYPLRNLQPASEYTVSLVA--IKGNQESP-KATGV 1081
+ RR P + + +++ + L S+Y + A G+ +P + G
Sbjct: 20432 ---VERRDLPDGRWTKASFTNVTETQFIISGLTQNSQYEFRVFARNAVGSISNPSEVVGP 20488
Query: 1082 FTTLQ----PGSSIPPYNTEVTE----TTIV----ITWTPAPRI-GFKLGVRPSQGGEAP 1128
T + P +P TEV + T++ I+ PAP I +K
Sbjct: 20489 ITCIDSYGGPVIDLPLEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVC 20548
Query: 1129 REVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDT 1188
E T+D SI++ Y +++ A I +++ PP
Sbjct: 20549 VENTTDLASILIKDADRLNSGCYELKLRNAMGSASATIRVQILDKPGPPGGPIEFKTVTA 20608
Query: 1189 GVLTVSWERSTTPD----ITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYN 1244
+T+ W R D IT Y + T+ + + E H ++ T + G EY
Sbjct: 20609 EKITLLW-RPPADDGGAKITHYIVEKRETSRVVWSMVSE--HLEECIITTTKIIKGNEYI 20665
Query: 1245 VSVYTVKDDKESVPI-SDTII----------PEVPQLTDLSFVDITDSSIGLRWT-PL-- 1290
V V P+ SD+++ P +P++T IT +S+ + W+ P+
Sbjct: 20666 FRVRAVNKYGIGEPLESDSVVAKNAFVTPGPPGIPEVT-----KITKNSMTVVWSRPIAD 20720
Query: 1291 NSSTIIGYRITVVAAGEGIPIFEDFVDSSVGYY------------TVTGLEPGIDYDISV 1338
S I GY E S+G++ VTGL DY V
Sbjct: 20721 GGSDISGY------------FLEKRDKKSLGWFKVLKETIRDTRQKVTGLTENSDYQYRV 20768
Query: 1339 ITLINGGE---SAPTTLTQQTAVP-----PPTDLRFTNIGPDTMRVTWAPP---PSIDLT 1387
+ G+ S P+ + A P PP +R + ++ + W+ P +T
Sbjct: 20769 CAVNAAGQGPFSEPSEF-YKAADPIDPPGPPAKIRIADSTKSSITLGWSKPVYDGGSAVT 20827
Query: 1388 NFLVRYSPVKNEE-DVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQ- 1445
++V + EE V++NL PG Y VS+V + P+ +
Sbjct: 20828 GYVVEIRQGEEEEWTTVSTKGEVRTTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEP 20887
Query: 1446 ---KTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRN 1502
K L++P ID S + ++ R P + ++ +R
Sbjct: 20888 VQAKDILEAPE-IDLDVALRTSVIAKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARY 20946
Query: 1503 SI---------TLTNLTPGT--EYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAAT 1551
SI T+ +T +Y+++I G +S + + + L+V +
Sbjct: 20947 SIENTDSSSLLTIPQVTRNDTGKYILTIENGVGEPKSSTVSVKVLDTPAACQKLQVKHVS 21006
Query: 1552 PTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGL-----KPGVDYT 1606
++ + WD P + I Y ++ + ++V K ++T L K +
Sbjct: 21007 RGTVTLLWDPPLIDGGSPIINYVIEKRDATKRTWSVVSHKCSSTSFKLIDLSEKTPFFFR 21066
Query: 1607 ITVYAVTGRGDSPASSKPISINYRTEIDKP-SQMQVTDVQDNSISVKW----LPSSSPVT 1661
+ G G+ +++P+ E+ P + + D S+ + W S +T
Sbjct: 21067 VLAENEIGIGEPCETTEPVK---AAEVPAPIRDLSMKDSTKTSVILSWTKPDFDGGSVIT 21123
Query: 1662 GYRVTTTPKNGPGPTKTKTAGPDQT-EMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAV 1720
Y V + G G AG +T E+ + L+ V+A+N G S P+ +
Sbjct: 21124 EYVV---ERKGKGEQTWSHAGISKTCEIEVSQLKEQSVLEFRVFAKNEKGLSDPVTIGPI 21180
Query: 1721 TNIDRPKGLAFT-DVDVDSIKIAWESPQ-GQVSRYRVTY-SSPEDGIHEL---FPAPDGE 1774
T K L T +VD+ I A + + G + Y P+ I L P + E
Sbjct: 21181 T----VKELIITPEVDLSDIPGAQVTVRIGHNVHLELPYKGKPKPSISWLKDGLPLKESE 21236
Query: 1775 -------EDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPT----DLKFTQ 1823
E+ L E+ + D+ + + + P+ ++F +
Sbjct: 21237 FVRFSKTENKITLSIKNAKKEHGGKYTVILDNAVCRIAVPITVITLGPPSKPKGPIRFDE 21296
Query: 1824 VTPTSLSAQWTPP----NVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKY 1879
+ S+ W P ++T Y + +T K + + ++ V L+ +Y
Sbjct: 21297 IKADSVILSWDVPEDNGGGEITCYSIEKRETSQTN-WKMVCSSVARTTFKVPNLVKDAEY 21355
Query: 1880 EVSVYALKDTLTSRPAQGVVTTLEN----VSPPRRARVTDATETTITISWRTKT----ET 1931
+ V A S+P + ++ PP + + + T ++++W
Sbjct: 21356 QFRVRAENRYGVSQPLVSSIIVAKHQFRIPGPPGKPVIYNVTSDGMSLTWDAPVYDGGSE 21415
Query: 1932 ITGFQVDAVPANGQTPIQRTIKP-DVRSYTITGLQPGTDYKIYLYTLNDNARSSP----V 1986
+TGF V+ N + P R Y TGL G DY+ +Y N SSP
Sbjct: 21416 VTGFHVEKKERNSILWQKVNTSPISGREYRATGLVEGLDYQFRVYAENSAGLSSPSDPSK 21475
Query: 1987 VIDASTAIDAPSNLRFLATTPNSLLVSWQPP----RARITGYIIKYEKPGSPPREVVPRP 2042
A + +D P ++ T ++ + W PP ++I GY I+ ++ G+
Sbjct: 21476 FTLAVSPVDPPGTPDYIDVTRETITLKWNPPLRDGGSKIVGYSIE-KRQGNERWVRCNFT 21534
Query: 2043 RPGVTEATITGLEPGTEYTIYVIA 2066
+ T+TGL PG Y +IA
Sbjct: 21535 DVSECQYTVTGLSPGDRYEFRIIA 21558
Score = 109 bits (272), Expect = 4e-23
Identities = 299/1423 (21%), Positives = 501/1423 (35%), Gaps = 243/1423 (17%)
Query: 728 VTEITASSFVVSW----VSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPG 783
+++I A + +SW ++ + VE GD L T TS + L+PG
Sbjct: 12629 ISDIDADACSLSWHIPLEDGGSNITNYIVEKCDVSRGDWVTAL-ASVTKTSCRVGKLIPG 12687
Query: 784 RKYIVNV-----YQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ--- 835
++YI V + ISE +++ P P + V +V+ I V W RP
Sbjct: 12688 QEYIFRVRAENRFGISEPLTSPKMVAQFPFGVPSEPKNARVTKVNKDCIFVAWDRPDSDG 12747
Query: 836 -APITGYRIVYSPS-----VEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQES 889
+PI GY I V+ + T + E + L G++Y+ IYA+ + S
Sbjct: 12748 GSPIIGYLIERKERNSLLWVKANDTLVRSTE----YPCAGLVEGLEYSFRIYALNKAGSS 12803
Query: 890 TPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPVN 945
P + T D P + ++VT V+++W P+ S + GY V+
Sbjct: 12804 PPSKPTEYVTARMPVDPPGKP---EVIDVTKSTVSLIWARPKHDGGSKIIGYFVEA--CK 12858
Query: 946 LPGEHGQRLPISRNTFAE----VTGLSPGVTYYFKVF---AVSHGRESKPLTAQQTTKLD 998
LPG+ R + + + TGL Y F+ AV+ S+P +
Sbjct: 12859 LPGDKWVRCNTAPHQIPQEEYTATGLEEKAQYQFRAIARTAVNISPPSEPSDPVTILAEN 12918
Query: 999 APTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQ----------YNVGPSV 1048
P + S + V+ G + + T G+P +
Sbjct: 12919 VPPRIDLSVAMKSLLTVK--------AGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGI 12970
Query: 1049 SKYPLRNL----------QPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEV 1098
RNL + + +YT++ G++ + V +PG PP + ++
Sbjct: 12971 KMAMQRNLCTLELFSVNRKDSGDYTITAENSSGSKSATIKLKVLD--KPG---PPASVKI 13025
Query: 1099 TE---TTIVITWTPAPRIG------FKLGVR-PSQGGEAPREVTSDSGSIVVSGLTPGVE 1148
+ +++W P G + + R S+ A T S V L G E
Sbjct: 13026 NKMYSDRAMLSWEPPLEDGGSEITNYIVDKRETSRPNWAQVSATVPITSCSVEKLIEGHE 13085
Query: 1149 YVYTIQVLRDGQERDAPIVNKVV--TPLSPPTNLH--LEANPDTGVLTVSWERSTT---P 1201
Y + I D + P PP + +N +TVSW+
Sbjct: 13086 YQFRICAENKYGVGDPVFTEPAIAKNPYDPPGRCDPPVISNITKDHMTVSWKPPADDGGS 13145
Query: 1202 DITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTV--------KDD 1253
ITGY + T + ++ + L G EY V + D
Sbjct: 13146 PITGYLLEKRETQAVNWTKVNRKPIIER-TLKATGLQEGTEYEFRVTAINKAGPGKPSDA 13204
Query: 1254 KESVPISDTIIPEVPQLTDLSFVDITDSSIGLRWTPL---NSSTIIGYRITVVAAGEGIP 1310
++ D P P + D T SS+ L W S IIGY + V A
Sbjct: 13205 SKAAYARDPQYPPGPPAFPKVY-DTTRSSVSLSWGKPAYDGGSPIIGYLVEVKRADS--- 13260
Query: 1311 IFEDFVDSSVGY------YTVTGLEPGIDYDISVITLINGGESAPTTL-----TQQTAVP 1359
+++V ++ + VTGL Y V + G S P+ + + +P
Sbjct: 13261 --DNWVRCNLPQNLQKTRFEVTGLMEDTQYQFRVYAVNKIGYSDPSDVPDKHYPKDILIP 13318
Query: 1360 P----PTDLRFTNI--GPDTMR----VTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISP 1409
P DLR T I TMR V PPP I + P N D L I
Sbjct: 13319 PEGELDADLRKTLILRAGVTMRLYVPVKGRPPPKITWS------KPNVNLRDRIGLDIKS 13372
Query: 1410 SDNAVVL----TNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSF 1465
+D L N +Y++++ + + E T + T P + +I+ +S
Sbjct: 13373 TDFDTFLRCENVNKYDAGKYILTLENSCGKKEYTIVVKVLDTP-GPPVNVTVKEISKDSA 13431
Query: 1466 TVHWIAP----RATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVA 1521
V W P + I Y ++ S+ S + NL G Y + A
Sbjct: 13432 YVTWEPPIIDGGSPIINYVVQKRDAERKSWSTV-TTECSKTSFRVANLEEGKSYFFRVFA 13490
Query: 1522 LNGREESPLLIGQQSTVSDVPR---------DLEVVAATPTSLLISWDAPAVTVRYYRIT 1572
E+ IG D + DL+V + + +S I W P I
Sbjct: 13491 -----ENEYGIGDPGETRDAVKASQTPGPVVDLKVRSVSKSSCSIGWKKPHSDGGSRIIG 13545
Query: 1573 YGETGGNSPVQEFTVPGSKSTATISGLK---------PGVDYTITVYAVTGRGDSPASSK 1623
Y V +F +K + L G +YT V A G+ S
Sbjct: 13546 Y--------VVDFLTEENKWQRVMKSLSLQYSAKDLTEGKEYTFRVSAENENGEGTPSE- 13596
Query: 1624 PISINYRTEIDKPSQMQVTDVQDNSISVKWLPS----SSPVTGYRVTTTPKNGPGPTKTK 1679
I++ R ++ P + +K LP + + +R+ K P P+ +
Sbjct: 13597 -ITVVARDDVVAP-----------DLDLKGLPDLCYLAKENSNFRLKIPIKGKPAPSVSW 13644
Query: 1680 TAGPD----QTEMTIEGLQPTVEYVV-----------SVYAQNPSGESQPLVQTAVTNID 1724
G D T +++E +V ++ +N +G + + V
Sbjct: 13645 KKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKEGTISIKVVGKP 13704
Query: 1725 R-PKG-LAFTDVDVDSIKIAWESPQGQVSRYRVTY-SSPEDGIHELFP--APDGEEDTAE 1779
P G + F +V +++ + W P+ Y D ++ + A ++ T
Sbjct: 13705 GIPTGPIKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDSVNNKWVTCASAVQKTTFR 13764
Query: 1780 LQGLRPGSEYTVSVVA-----LHDDMESQPLIGTQSTAIP-APTDLKFTQVTPTSLSAQW 1833
+ L G EYT V A + + ++S+P++ +P AP V S+S W
Sbjct: 13765 VTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVPDAPPPPNIVDVRHDSVSLTW 13824
Query: 1834 TPP----NVQLTGYRVRVTPKEKTGPM-KEINLAP-DSSSVVVSGLMVATKYEVSVYAL- 1886
T P +TGY + KE+ + K N P V+GL +YE V A+
Sbjct: 13825 TDPKKTGGSPITGYHLEF--KERNSLLWKRANKTPIRMRDFKVTGLTEGLEYEFRVMAIN 13882
Query: 1887 -----KDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKT----ETITGFQV 1937
K +L S P V L+ + PP + V + T ++T+ W +TG+ V
Sbjct: 13883 LAGVGKPSLPSEP----VVALDPIDPPGKPEVINITRNSVTLIWTEPKYDGGHKLTGYIV 13938
Query: 1938 DA--VPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLN 1978
+ +P+ P+ ++T+T L G Y+ + N
Sbjct: 13939 EKRDLPSKSWMKANHVNVPEC-AFTVTDLVEGGKYEFRIRAKN 13980
Score = 108 bits (269), Expect = 9e-23
Identities = 265/1341 (19%), Positives = 468/1341 (34%), Gaps = 163/1341 (12%)
Query: 780 LLPGRKYIVNVYQISEDGE----QSLILSTSQTTAPDAPPD-PTVDQVDDTSIVVRWSRP 834
L+ G +YI V ++ G+ QS + P PP+ P V V + V W RP
Sbjct: 14164 LIQGNEYIFRVSAVNHYGKGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSWKRP 14223
Query: 835 Q----APITGYRIVYSPSVEGSSTE-LNLPETANSVTLSDLQPGVQYNITIYA-----VE 884
+ ITGY + + P + ++ LQ G Y + A +
Sbjct: 14224 VDDGGSEITGYHVERREKKSLRWVRAIKTPVSDLRCKVTGLQEGSTYEFRVSAENRAGIG 14283
Query: 885 ENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPES----AVTGYRVD 940
E++ V+ ++ P + P D T ++ W P +TGY V+
Sbjct: 14284 PPSEASDSVLMKDAAYPPGPPSNPHVTD-----TTKKSASLAWGKPHYDGGLEITGYVVE 14338
Query: 941 VIPVN----LPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQ--QT 994
V + G L I++ V L Y F++ A++ +P +
Sbjct: 14339 HQKVGDEAWIKDTTGTALRITQFV---VPDLQTKEKYNFRISAINDAGVGEPAVIPDVEI 14395
Query: 995 TKLDAPTNLQFVNETDSTVLVR-------WTP----PRAQITGYRLTVGLTRRGQPRQYN 1043
+ + + + E T++VR + P P ++T + + L R
Sbjct: 14396 VEREMAPDFELDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKNRANIENTE 14455
Query: 1044 VGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTI 1103
++ P N ++ +++ G + V T P ++ P T++T+ ++
Sbjct: 14456 -SFTLLIIPECNRYDTGKFVMTIENPAGKKSGFVNVRVLDTPGPVLNLRP--TDITKDSV 14512
Query: 1104 VITWT-PAPRIGFKLGVRPSQGGEAPREVTSDSGS------IVVSGLTPGVEYVYTIQVL 1156
+ W P G ++ + EA R+ S + + V+GL+ G EY + +
Sbjct: 14513 TLHWDLPLIDGGSRITNYIVEKREATRKSYSTATTKCHKCTYKVTGLSEGCEYFFRVMAE 14572
Query: 1157 RD---GQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPD---ITGYRITT 1210
+ G+ + K SPP +L++ + ++++W + ITGY I
Sbjct: 14573 NEYGIGEPTETTEPVKASEAPSPPDSLNI-MDITKSTVSLAWPKPKHDGGSKITGYVIEA 14631
Query: 1211 TPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISD--TIIPEVP 1268
Q + V + C NL+ G EY V V S P I+ E
Sbjct: 14632 QRKGSDQWTHITTVKGLE---CVVRNLTEGEEYTFQVMAVNSAGRSAPRESRPVIVKEQT 14688
Query: 1269 QLTDLSFVDITDSSIGLRWTPLNSSTI--IGYRITVVAAGEGIPI--------FEDFVDS 1318
L +L I + + I +G V +G I FE S
Sbjct: 14689 MLPELDLRGIYQKLVIAKAGDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATS 14748
Query: 1319 SVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTW 1378
++ Y ++ ++ T PP ++F + D + +W
Sbjct: 14749 TILNINECVRSDSGPYPLTARNIVGEVGDVITIQVHDIPGPPTGPIKFDEVSSDFVTFSW 14808
Query: 1379 APPPS---IDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSS---- 1431
PP + + ++N++V + V EL+ + T L G EY V +
Sbjct: 14809 DPPENDGGVPISNYVVEMRQTDSTTWV-ELATTVIRTTYKATRLTTGLEYQFRVKAQNRY 14867
Query: 1432 -VYEQHESTPLRGRQKTGLDSPTGI-DFSDITANSFTVHWIAP----RATITGYRIRHHP 1485
V S + + P G + +T +S T+ W P + I GY +
Sbjct: 14868 GVGPGITSACIVANYPFKVPGPPGTPQVTAVTKDSMTISWHEPLSDGGSPILGYHVERKE 14927
Query: 1486 EHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN-------GREESPLLIGQQSTV 1538
+ + N + LT G Y ++A N + P+L
Sbjct: 14928 RNGILWQTVSKALVPGNIFKSSGLTDGIAYEFRVIAENMAGKSKPSKPSEPMLALDPIDP 14987
Query: 1539 SDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPG----SKSTA 1594
P L + T T + W P T + +Y + P + ++
Sbjct: 14988 PGKPVPLNITRHTVT---LKWAKPEYTGGFKITSYIVEKRDLPNGRWLKANFSNILENEF 15044
Query: 1595 TISGLKPGVDYTITVYAVTGRGD-SPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKW 1653
T+SGL Y V A G SP S +I R +++ P +D I
Sbjct: 15045 TVSGLTEDAAYEFRVIAKNAAGAISPPSEPSDAITCRDDVEAPKIKVDVKFKDTVI---- 15100
Query: 1654 LPSSSPVTGYRVTTTPKNGPGPTK------TKTAGPDQTEMTIEGLQPTV---------E 1698
+R+ P PT + G + E+ I +
Sbjct: 15101 ---LKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDS 15157
Query: 1699 YVVSVYAQNPSGESQPLVQTAVTNIDRP----KGLAFTDVDVDSIKIAWESP---QGQVS 1751
++ A NP G ++ + V +DRP LA T+V + ++W P G
Sbjct: 15158 GAYTLTATNPGGFAKHIFNVKV--LDRPGPPEGPLAVTEVTSEKCVLSWFPPLDDGGAKI 15215
Query: 1752 RYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALH-----DDMESQPLI 1806
+ + + A + + ++ L G+EY V+A++ + +ES+P++
Sbjct: 15216 DHYIVQKRETSRLAWTNVASEVQVTKLKVTKLLKGNEYIFRVMAVNKYGVGEPLESEPVL 15275
Query: 1807 GTQSTAIP-APTDLKFTQVTPTSLSAQWTPPN----VQLTGYRVRVTPKEKTGPMKEINL 1861
P P + + T +T S+ W P+ ++ Y V K +K
Sbjct: 15276 AVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEIINYIVERRDKAGQRWIKCNKK 15335
Query: 1862 APDSSSVVVSGLMVATKYEVSVYA-----LKDTLTSRPAQGVVTTLENVSPPRRARVTDA 1916
VSGL +YE + A + + P T+ PP RV D
Sbjct: 15336 TLTDLRYKVSGLTEGHEYEFRIMAENAAGISAPSPTSPFYKACDTVFKPGPPGNPRVLDT 15395
Query: 1917 TETTITISWRTKT----ETITGFQVD-AVPANGQTPIQRTIKP----DVRSYTITGLQPG 1967
+ ++I+I+W ITG+ V+ A+P + I + P SYTITGL
Sbjct: 15396 SRSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQI---VTPPAGLKATSYTITGLTEN 15452
Query: 1968 TDYKIYLYTLNDNARSSPVVI 1988
+YKI +Y +N P ++
Sbjct: 15453 QEYKIRIYAMNSEGLGEPALV 15473
Score = 106 bits (265), Expect = 2e-22
Identities = 320/1538 (20%), Positives = 543/1538 (35%), Gaps = 226/1538 (14%)
Query: 702 TSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSW----VSASDTVSGFRVEYELS 757
T P S V +T P VT+++ V W +++G+ +E
Sbjct: 12006 TGPPTESKPVIAKTKYDKPGRPDPPEVTKVSKEEMTVVWNPPEYDGGKSITGYFLE---K 12062
Query: 758 EEGDEPQYLDLPSTATS---VNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDA- 813
+E +++ + +A + + +LLP +Y V +E G L + A D
Sbjct: 12063 KEKHSTRWVPVNKSAIPERRMKVQNLLPDHEYQFRVKAENEIGIGEPSLPSRPVVAKDPI 12122
Query: 814 --PPDPTVDQVDDT---SIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANS 864
P PT +V DT SI + W +P API GY + P + +S + +
Sbjct: 12123 EPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAPIIGYVVEMRPKIADASPDEGWKRCNAA 12182
Query: 865 VTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGT------------------PRSDT 906
L V+ T+ +++ENQE V Q G P D
Sbjct: 12183 AQL------VRKEFTVTSLDENQEYEFRVCAQNQVGIGRPAELKEAIKPKEILEPPEIDL 12236
Query: 907 VPSPRDLQFVEV-TDVKV-TIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEV 964
S R L V +++ I+ P VT +V + V GQ + F +
Sbjct: 12237 DASMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVV---RKGQVDLVDTMAFLVI 12293
Query: 965 TGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAP-TNLQFVNETDSTVLVRWTPPR-- 1021
+ + + + V+ E + P ++L+ + T ++ V W PP
Sbjct: 12294 PNSTRDDSGKYSLTLVNPAGEKAVFVNVRVLDTPGPVSDLKVSDVTKTSCHVSWAPPEND 12353
Query: 1022 --AQITGYRLTVGLTRRGQPRQYNVGPSVSK--YPLRNLQPASEYTVSLVAIKGNQESPK 1077
+Q+T Y V + V P V K + + NL P +EY + A+ N+ P
Sbjct: 12354 GGSQVTHY--IVEKREADRKTWSTVTPEVKKTSFHVTNLVPGNEYYFRVTAV--NEYGPG 12409
Query: 1078 ATG-----VFTTLQPGSSIPPYNTEVTETT---IVITWTPAPRIG-FKLG--VRPSQGGE 1126
V + PP EVTE T + W P R G K+ + + E
Sbjct: 12410 VPTDVPKPVLASDPLSEPDPPRKLEVTEMTKNSATLAWLPPLRDGGAKIDGYITSYREEE 12469
Query: 1127 APREVTSDSG-----SIVVSGLTPGVEYVYTI---QVLRDGQERDAPIVNKVVTPLSPPT 1178
P + ++ S+VV+GL G +Y + + + R+A V + L PP
Sbjct: 12470 QPADRWTEYSVVKDLSLVVTGLKEGKKYKFRVAARNAVGVSLPREAEGVYEAKEQLLPPK 12529
Query: 1179 NL-----------------HLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSL 1221
L H+ P T W++ +T + + +
Sbjct: 12530 ILMPEQITIKAGKKLRIEAHVYGKPHP---TCKWKKGEDEVVTSSHLAVHKADSSSILII 12586
Query: 1222 EEVVHADQS--SCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPEVPQLTDLSFVDIT 1279
++V D S T +N S K V + D P P D+S DI
Sbjct: 12587 KDVTRKDSGYYSLTAENSSG----------TDTQKIKVVVMDAPGPPQPPF-DIS--DID 12633
Query: 1280 DSSIGLRW-TPLNS--STIIGYRITV--VAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDY 1334
+ L W PL S I Y + V+ G+ + +S V L PG +Y
Sbjct: 12634 ADACSLSWHIPLEDGGSNITNYIVEKCDVSRGDWVTALASVTKTSC---RVGKLIPGQEY 12690
Query: 1335 DISVITLINGGESAPTTLTQQTAVPP------PTDLRFTNIGPDTMRVTWAPPPSIDLTN 1388
V G S P T + A P P + R T + D + V W P S D +
Sbjct: 12691 IFRVRAENRFGISEPLTSPKMVAQFPFGVPSEPKNARVTKVNKDCIFVAWDRPDS-DGGS 12749
Query: 1389 FLVRYSPVKNEEDVAELSISPSDNAVVLTN-----LLPGTEYVVSVSSVYEQHESTPLRG 1443
++ Y ++ +E + L + +D V T L+ G EY + ++ + S P +
Sbjct: 12750 PIIGYL-IERKERNSLLWVKANDTLVRSTEYPCAGLVEGLEYSFRIYALNKAGSSPPSKP 12808
Query: 1444 RQ----KTGLDSPTGIDFSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPRED 1495
+ + +D P + D+T ++ ++ W P+ + I GY + R +
Sbjct: 12809 TEYVTARMPVDPPGKPEVIDVTKSTVSLIWARPKHDGGSKIIGYFVEACKLPGDKWVRCN 12868
Query: 1496 RVPHS--RNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTV---SDVPRDLEVVAA 1550
PH + T T L +Y +A SP +VP +++ A
Sbjct: 12869 TAPHQIPQEEYTATGLEEKAQYQFRAIARTAVNISPPSEPSDPVTILAENVPPRIDLSVA 12928
Query: 1551 TPTSLLIS------WDAPAVTVRYYRITYGETGGN-SPVQEFTVPGSKSTATIS----GL 1599
+ L + DA +++ + G P + + ++ T+
Sbjct: 12929 MKSLLTVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNR 12988
Query: 1600 KPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLP---- 1655
K DYTIT S + S I + + P+ +++ + + + W P
Sbjct: 12989 KDSGDYTITA-----ENSSGSKSATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLED 13043
Query: 1656 SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPL 1715
S +T Y V + P + P T ++E L EY + A+N G P+
Sbjct: 13044 GGSEITNYIVDKRETSRPNWAQVSATVPI-TSCSVEKLIEGHEYQFRICAENKYGVGDPV 13102
Query: 1716 -VQTAVT-NIDRPKGLA----FTDVDVDSIKIAWESPQGQ----VSRYRVTYSSPEDGIH 1765
+ A+ N P G +++ D + ++W+ P ++ Y + +
Sbjct: 13103 FTEPAIAKNPYDPPGRCDPPVISNITKDHMTVSWKPPADDGGSPITGYLLEKRETQAVNW 13162
Query: 1766 ELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAI------PAPTDL 1819
E T + GL+ G+EY V A++ +P +++ P P
Sbjct: 13163 TKVNRKPIIERTLKATGLQEGTEYEFRVTAINKAGPGKPSDASKAAYARDPQYPPGPPAF 13222
Query: 1820 -KFTQVTPTSLSAQWTPPNVQ----LTGYRVRVTPKEKTGPMKEINLAPD--SSSVVVSG 1872
K T +S+S W P + GY V V + ++ NL + + V+G
Sbjct: 13223 PKVYDTTRSSVSLSWGKPAYDGGSPIIGYLVEVKRADSDNWVR-CNLPQNLQKTRFEVTG 13281
Query: 1873 LMVATKYEVSVYALKDTLTSRPAQ--GVVTTLENVSPPRRARVTDATETTITISWRTKTE 1930
LM T+Y+ VYA+ S P+ + + PP D +T I + T
Sbjct: 13282 LMEDTQYQFRVYAVNKIGYSDPSDVPDKHYPKDILIPPEGELDADLRKTLILRAGVTMRL 13341
Query: 1931 TITGFQVDAVPANGQTPIQRT-IKPDVRSYTITGLQ-PGTDYKIYLYTLNDN-------- 1980
VP G+ P + T KP+V GL TD+ +L N N
Sbjct: 13342 --------YVPVKGRPPPKITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKYI 13393
Query: 1981 --------ARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPP----RARITGYIIKY 2028
+ +V+ P N+ + +S V+W+PP + I Y+++
Sbjct: 13394 LTLENSCGKKEYTIVVKVLDTPGPPVNVTVKEISKDSAYVTWEPPIIDGGSPIINYVVQK 13453
Query: 2029 EKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIA 2066
V T + LE G Y V A
Sbjct: 13454 RDAERKSWSTV-TTECSKTSFRVANLEEGKSYFFRVFA 13490
Score = 102 bits (255), Expect = 4e-21
Identities = 274/1373 (19%), Positives = 474/1373 (34%), Gaps = 187/1373 (13%)
Query: 766 LDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDT 825
+DL T + IP+ ++ ++ GE+++ ++ P D V V T
Sbjct: 12282 VDLVDTMAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFVNVRVLDTPGPVSDLKVSDVTKT 12341
Query: 826 SIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETAN-SVTLSDLQPGVQYNITI 880
S V W+ P+ + +T Y IV + + PE S +++L PG +Y +
Sbjct: 12342 SCHVSWAPPENDGGSQVTHY-IVEKREADRKTWSTVTPEVKKTSFHVTNLVPGNEYYFRV 12400
Query: 881 YAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTG 936
AV E P + + + PR L+ E+T T+ W PP + + G
Sbjct: 12401 TAVNEYGPGVPTDVPKPVLASDPLSEPDPPRKLEVTEMTKNSATLAWLPPLRDGGAKIDG 12460
Query: 937 YRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTK 996
Y P + + ++ VTGL G Y F+V A+
Sbjct: 12461 YITSYREEEQPADRWTEYSVVKDLSLVVTGLKEGKKYKFRV------------AARNAVG 12508
Query: 997 LDAPTNLQFVNETDSTVLVRWTPPR----AQIT---GYRLTVGLTRRGQPR--------- 1040
+ P + V E +L PP+ QIT G +L + G+P
Sbjct: 12509 VSLPREAEGVYEAKEQLL----PPKILMPEQITIKAGKKLRIEAHVYGKPHPTCKWKKGE 12564
Query: 1041 ---------QYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSI 1091
+ S S ++++ SL A + + V PG
Sbjct: 12565 DEVVTSSHLAVHKADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPGPPQ 12624
Query: 1092 PPYN-TEVTETTIVITW-TPAPRIGFKL------GVRPSQGGEAPREVTSDSGSIVVSGL 1143
PP++ +++ ++W P G + S+G + S V L
Sbjct: 12625 PPFDISDIDADACSLSWHIPLEDGGSNITNYIVEKCDVSRGDWVTALASVTKTSCRVGKL 12684
Query: 1144 TPGVEYVYTIQVLRDGQERDAPIVNKVV------TPLSPPTNLHLEANPDTGVLTVSWER 1197
PG EY++ ++ + K+V P P + N D + V+W+R
Sbjct: 12685 IPGQEYIFRVRAENRFGISEPLTSPKMVAQFPFGVPSEPKNARVTKVNKD--CIFVAWDR 12742
Query: 1198 STT---PDITGYRITTTPTNGQQG-NSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDD 1253
+ I GY I N + + +V + + C L GLEY+ +Y +
Sbjct: 12743 PDSDGGSPIIGYLIERKERNSLLWVKANDTLVRSTEYPCA--GLVEGLEYSFRIYALNKA 12800
Query: 1254 KESVPISDTIIPEVPQLTD----LSFVDITDSSIGLRWTPL---NSSTIIGYRITVV--- 1303
S P T D +D+T S++ L W S IIGY +
Sbjct: 12801 GSSPPSKPTEYVTARMPVDPPGKPEVIDVTKSTVSLIWARPKHDGGSKIIGYFVEACKLP 12860
Query: 1304 --------AAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVI--TLIN----GGESAP 1349
A IP E YT TGLE Y I T +N S P
Sbjct: 12861 GDKWVRCNTAPHQIPQEE---------YTATGLEEKAQYQFRAIARTAVNISPPSEPSDP 12911
Query: 1350 TTLTQQTAVPPPTDLRF-----------TNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKN 1398
T+ + VPP DL TN+ D V P P++ P +
Sbjct: 12912 VTILAEN-VPPRIDLSVAMKSLLTVKAGTNVCLDA-TVFGKPMPTVSWKKDGTLLKPAEG 12969
Query: 1399 EEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHEST-PLRGRQKTGLDSPTGIDF 1457
+ + ++ + + N +Y ++ + +T L+ K G P +
Sbjct: 12970 IKMAMQRNLCTLE--LFSVNRKDSGDYTITAENSSGSKSATIKLKVLDKPG--PPASVKI 13025
Query: 1458 SDITANSFTVHWIAP----RATITGYRIRHHPEHFSGRPREDRVPHS--RNSITLTNLTP 1511
+ + ++ + W P + IT Y + + + RP +V + S ++ L
Sbjct: 13026 NKMYSDRAMLSWEPPLEDGGSEITNYIV---DKRETSRPNWAQVSATVPITSCSVEKLIE 13082
Query: 1512 GTEYVVSIVALNGREESPLLIGQQSTVS---DVPR--DLEVVA-ATPTSLLISWDAPA-- 1563
G EY I A N + + + D P D V++ T + +SW PA
Sbjct: 13083 GHEYQFRICAENKYGVGDPVFTEPAIAKNPYDPPGRCDPPVISNITKDHMTVSWKPPADD 13142
Query: 1564 --VTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRG---DS 1618
+ Y + ET + + P + T +GL+ G +Y V A+ G S
Sbjct: 13143 GGSPITGYLLEKRETQAVNWTKVNRKPIIERTLKATGLQEGTEYEFRVTAINKAGPGKPS 13202
Query: 1619 PASSKPISINYRTEIDKPSQMQVTDVQDNSISVKW----LPSSSPVTGYRVTTTPKNGPG 1674
AS + + + P+ +V D +S+S+ W SP+ GY V +
Sbjct: 13203 DASKAAYARDPQYPPGPPAFPKVYDTTRSSVSLSWGKPAYDGGSPIIGYLVEVKRADSDN 13262
Query: 1675 PTKTK-TAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFT- 1732
+ +T + GL +Y VYA N G S P + V + PK +
Sbjct: 13263 WVRCNLPQNLQKTRFEVTGLMEDTQYQFRVYAVNKIGYSDP---SDVPDKHYPKDILIPP 13319
Query: 1733 --DVDVDSIKIAWESPQGQVSRY---------RVTYSSPEDGIHELFPAPDGEED----- 1776
++D D K + Y ++T+S P + + D
Sbjct: 13320 EGELDADLRKTLILRAGVTMRLYVPVKGRPPPKITWSKPNVNLRDRIGLDIKSTDFDTFL 13379
Query: 1777 TAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPP 1836
E +Y +++ E ++ T P P ++ +++ S W PP
Sbjct: 13380 RCENVNKYDAGKYILTLENSCGKKEYTIVVKVLDTPGP-PVNVTVKEISKDSAYVTWEPP 13438
Query: 1837 NVQ----LTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTS 1892
+ + Y V+ E+ + +S V+ L Y V+A +
Sbjct: 13439 IIDGGSPIINYVVQKRDAERKS-WSTVTTECSKTSFRVANLEEGKSYFFRVFAENEYGIG 13497
Query: 1893 RPAQ--GVVTTLENVSPPRRARVTDATETTITISWRTK----TETITGFQVDAVPANGQT 1946
P + V + P +V ++++ +I W+ I G+ VD + +
Sbjct: 13498 DPGETRDAVKASQTPGPVVDLKVRSVSKSSCSIGWKKPHSDGGSRIIGYVVDFLTEENKW 13557
Query: 1947 PIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSP--VVIDASTAIDAP 1997
QR +K Y+ L G +Y + N+N +P + + A + AP
Sbjct: 13558 --QRVMKSLSLQYSAKDLTEGKEYTFRVSAENENGEGTPSEITVVARDDVVAP 13608
Score = 102 bits (255), Expect = 4e-21
Identities = 306/1554 (19%), Positives = 528/1554 (33%), Gaps = 201/1554 (12%)
Query: 610 GPVEVFITETPSQPNSHPIQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSY 666
GP E + T + WN P ++IS YI+ R + + W + + +Y
Sbjct: 18431 GPPEGPLKVTGVTAEKCYLAWNPPLQDGGANISHYIIEKRETSRLS-WTQVSTEVQALNY 18489
Query: 667 TIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSE 726
+ L PG Y +++++ +YG E P+ S VT P ++
Sbjct: 18490 KVTKLLPGNEYIFRVMAVNKYGIGE-------------PLESGPVTACNPYKPPGPPSTP 18536
Query: 727 SVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDE-----PQYLDLPSTATSVNIPDLL 781
V+ IT S VV+W D G +E + E+ D+ + T + + L
Sbjct: 18537 EVSAITKDSMVVTWARPVDD-GGTEIEGYILEKRDKEGVRWTKCNKKTLTDLRLRVTGLT 18595
Query: 782 PGRKY-----IVNVYQISEDGEQSLILSTSQTTAPDAPP-DPTVDQVDDTSIVVRWSRP- 834
G Y N + E E S+ P PP +P V +S+ + WS+P
Sbjct: 18596 EGHSYEFRVAAENAAGVGEPSEPSVFYRACDALYPPGPPSNPKVTDTSRSSVSLAWSKPI 18655
Query: 835 ---QAPITGYRIVYSPSVEGSSTELNLPE--TANSVTLSDLQPGVQYNITIYAVEENQES 889
AP+ GY + + T P T++ L+ +YN I A+
Sbjct: 18656 YDGGAPVKGYVVEVKEAAADEWTTCTPPTGLQGKQFTVTKLKENTEYNFRICAINSEGVG 18715
Query: 890 TPVVIQQETTGTPRSD--TVPSPRDLQFVEVTDVKVTI-----MWTPPESAVTGYRVDVI 942
P + R + + DL+ V V T+ + PE V + + I
Sbjct: 18716 EPATLPGSVVAQERIEPPEIELDADLRKVVVLRASATLRLFVTIKGRPEPEVKWEKAEGI 18775
Query: 943 PVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTN 1002
+ + + VT G Y + G ++ + + AP N
Sbjct: 18776 LTD-RAQIEVTSSFTMLVIDNVTRFDSG--RYNLTLENNSGSKTAFVNVRVLDSPSAPVN 18832
Query: 1003 LQFVNETDSTVLVRWTPP----RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQP 1058
L +V + W PP A+IT Y + T R + + + + NLQ
Sbjct: 18833 LTIREVKKDSVTLSWEPPLIDGGAKITNYIVEKRETTRKAYATITNNCTKTTFRIENLQE 18892
Query: 1059 ASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYN------TEVTETTIVITW-TPAP 1111
Y ++A + E TT S PP +VT T I W P
Sbjct: 18893 GCSYYFRVLA---SNEYGIGLPAETTEPVKVSEPPLPPGRVTLVDVTRNTATIKWEKPES 18949
Query: 1112 RIGFKLG----VRPSQGGEAPREVTS-DSGSIVVSGLTPGVEYVYTIQVLR-----DGQE 1161
G K+ ++G E T + +SGLT G EYV+ + + D ++
Sbjct: 18950 DGGSKITGYVVEMQTKGSEKWSTCTQVKTLEATISGLTAGEEYVFRVAAVNEKGRSDPRQ 19009
Query: 1162 RDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDIT-GYRITTTPTNGQQGNS 1220
P++ + + + P L V D+ R T + G +
Sbjct: 19010 LGVPVIARDI-EIKPSVELPFH------TFNVKAREQLKIDVPFKGRPQATVNWRKDGQT 19062
Query: 1221 LEEVVHADQSS---CTFDNLSPGLEYNVSVY--TVKDDKESVPISDTII------PEVPQ 1269
L+E + SS T ++ + +V Y V + S+ + TII P P
Sbjct: 19063 LKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSNSAGSITVPITIIVLDRPGPPGPI 19122
Query: 1270 LTDLSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIFEDFVDSSVGYYT--VTG 1327
D +++ SI + W P +V E V +V + +
Sbjct: 19123 RID----EVSCDSITISWNPPEYDGGCQISNYIVEKKETTSTTWHIVSQAVARTSIKIVR 19178
Query: 1328 LEPGIDYDISVITLINGGESAPTTLTQQTA------VPPPTDLRFTNIGPDTMRVTWAPP 1381
L G +Y V G+S+ + + A PP + + TM VTW P
Sbjct: 19179 LTTGSEYQFRVCAENRYGKSSYSESSAVVAEYPFSPPGPPGTPKVVHATKSTMLVTWQVP 19238
Query: 1382 PSIDLTNFLVRYSPVKNEEDV---AELSISPSDNAVVLTNLLPGTEY--------VVSVS 1430
+ + + + K + I +D + ++ L G Y + +
Sbjct: 19239 VNDGGSRVIGYHLEYKERSSILWSKANKILIADTQMKVSGLDEGLMYEYRVYAENIAGIG 19298
Query: 1431 SVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPR----ATITGYRIRHHPE 1486
+ E P R D P + ++IT S ++ W P A ITGY + E
Sbjct: 19299 KCSKSCEPVPAR----DPCDPPGQPEVTNITRKSVSLKWSKPHYDGGAKITGYIVERR-E 19353
Query: 1487 HFSGRPREDRVPHSRNS-ITLTNLTPGTEYVVSIVALNGREE--------SPLLIGQQST 1537
GR + + + + +T LT Y + A N + P+++
Sbjct: 19354 LPDGRWLKCNYTNIQETYFEVTELTEDQRYEFRVFARNAADSVSEPSESTGPIIVKDDVE 19413
Query: 1538 VSDVPRDLE----VVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKST 1593
V D++ +V L I+ D + I++ + G + T S
Sbjct: 19414 PPRVMMDVKFRDVIVVKAGEVLKINADIAGRPLPV--ISWAKDGIEIEERARTEIISTDN 19471
Query: 1594 ATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKP----SQMQVTDVQDNSI 1649
T+ +K + Y +T + + A ++ +++N + +DKP +++ +
Sbjct: 19472 HTLLTVKDCIRRDTGQYVLTLK--NVAGTRSVAVNCKV-LDKPGPPAGPLEINGLTAEKC 19528
Query: 1650 SVKW---LPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQ 1706
S+ W Y + + T + L EY+ V
Sbjct: 19529 SLSWGRPQEDGGADIDYYIVEKRETSHLAWTICEGELQMTSCKVTKLLKGNEYIFRVTGV 19588
Query: 1707 NPSGESQPLVQTAVTNID------RPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSP 1760
N G +PL A+ +D P L T V +S+ + W P+ Y
Sbjct: 19589 NKYGVGEPLESVAIKALDPFTVPSPPTSLEITSVTKESMTLCWSRPESDGGSEISGYIIE 19648
Query: 1761 EDGIHELFPAPDGEEDTAELQ----GLRPGSEYTVSVVA-----LHDDMESQPLIGTQST 1811
+ L ++ +L+ GLR G EY V A L E+ PLI +
Sbjct: 19649 RREKNSLRWVRVNKKPVYDLRVKSTGLREGCEYEYRVYAENAAGLSLPSETSPLIRAEDP 19708
Query: 1812 A-IPA-PTDLKFTQVTPTSLSAQWTPP----NVQLTGYRVRVTPKEKTGPMKEINLAPDS 1865
+P+ P+ K T+++ W P +TGY V + T I +
Sbjct: 19709 VFLPSPPSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEYKKSDDTDWKTSIQ-SLRG 19767
Query: 1866 SSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENV----------SPPRRARVTD 1915
+ +SGL +Y V ++ S P+ + S R+ +
Sbjct: 19768 TEYTISGLTTGAEYVFRVKSVNKVGASDPSDSSDPQIAKEREEEPLFDIDSEMRKTLIVK 19827
Query: 1916 A-TETTITISWRTK-----------TETITGFQVDAVPANGQTPIQRTIKPDVRSYTITG 1963
A T+T+ +R + T+ T VD + I+ + D YT+T
Sbjct: 19828 AGASFTMTVPFRGRPVPNVLWSKPDTDLRTRAYVDTTDSRTSLTIENANRNDSGKYTLT- 19886
Query: 1964 LQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPP 2017
+Q +A S +V+ P+N+ T S ++SW P
Sbjct: 19887 IQNVL-----------SAASLTLVVKVLDTPGPPTNITVQDVTKESAVLSWDVP 19929
Score = 102 bits (255), Expect = 4e-21
Identities = 136/661 (20%), Positives = 242/661 (36%), Gaps = 91/661 (13%)
Query: 1514 EYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVT----VRYY 1569
+Y + +G++ + +L+ T P ++V + S+ I+W+ P + V Y
Sbjct: 23142 KYTIEAENQSGKKSATVLVKVYDTPGPCP-SVKVKEVSRDSVTITWEIPTIDGGAPVNNY 23200
Query: 1570 RITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYA--VTGRGDSPASSKPISI 1627
+ E + + T SK+ ISGL G Y V + G G+ +S + +
Sbjct: 23201 IVEKREAAMRA-FKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYGIGEPCETSDAVLV 23259
Query: 1628 NYRTEIDKPSQMQVTDVQDNSISVKW----LPSSSPVTGYRVTTTPKNGPGPTKTKTAGP 1683
+ + P++++V DV +++++ W S +TGY + K T P
Sbjct: 23260 SEVPLV--PAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGTERWMKVVTLKP 23317
Query: 1684 DQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAW 1743
E T+ L +Y+ + AQN G S+P + + L D+ K
Sbjct: 23318 TVLEHTVTSLNEGEQYLFRIRAQNEKGVSEPRETVTAVTVQDLRVLPTIDLSTMPQKTI- 23376
Query: 1744 ESPQGQVSRYRVTYSSPEDGIHELFPAPDG--EEDTAELQGLRPGSEYTVSVVALHDD-- 1799
P G+ + + F A E + ++ ++ T+ + D
Sbjct: 23377 HVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAKLTIRETTIRDTGE 23436
Query: 1800 --MESQPLIGTQSTAI---------PAPTDLKFTQVTPTSLSAQWTPPNVQ----LTGYR 1844
+E + + GT S I P +K ++ TS++ W PP + L+GY
Sbjct: 23437 YTLELKNVTGTTSETIKVIILDKPGPPTGPIKIDEIDATSITISWEPPELDGGAPLSGYV 23496
Query: 1845 VRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLEN 1904
V + G + P S SV S E + Y + T+R G E
Sbjct: 23497 VEQRDAHRPGWL------PVSESVTRSTFKFTRLTEGNEYVFRVAATNRFGIGSYLQSEV 23550
Query: 1905 VS---------PPRRARVTDATETTITISWRTKTET----ITGFQVDAVPANGQTPIQRT 1951
+ PP ++ D + +T++W + +TG+ V+ ++
Sbjct: 23551 IECRSSIRIPGPPETLQIFDVSRDGMTLTWYPPEDDGGSQVTGYIVERKEVRADRWVRVN 23610
Query: 1952 IKP-DVRSYTITGLQPGTDYKIYLYTLNDNARSSP-------VVIDASTAIDAPSNLRFL 2003
P + Y TGL G +Y+ + +N P V +D P N R
Sbjct: 23611 KVPVTMTRYRSTGLTEGLEYEHRVTAINARGSGKPSRPSKPIVAMDPIAPPGKPQNPRVT 23670
Query: 2004 ATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTE 2059
TT S+ ++W P +++TGY+I+ +K + E T+T L G E
Sbjct: 23671 DTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTKCNTTPTKIREYTLTHLPQGAE 23730
Query: 2060 YTIYVIALKNNQKSEPLIGRKKTDELPQLVTLPHPNLHGPEILDVPSTVQKTPFVTHPGY 2119
Y V+A EP +VP TV+ T + +P Y
Sbjct: 23731 YRFRVLACNAGGPGEP--------------------------AEVPGTVKVTEMLEYPDY 23764
Query: 2120 D 2120
+
Sbjct: 23765 E 23765
Score = 100 bits (248), Expect = 2e-20
Identities = 162/726 (22%), Positives = 275/726 (37%), Gaps = 92/726 (12%)
Query: 1268 PQLTDLSFVDITDSSIGLRWTPLN---SSTIIGYRITVVAAGEG--IPIFEDFVDSSVGY 1322
P + +I +SI + W P + + GY + A +P+ E S+
Sbjct: 23462 PPTGPIKIDEIDATSITISWEPPELDGGAPLSGYVVEQRDAHRPGWLPVSESVTRST--- 23518
Query: 1323 YTVTGLEPGIDYDISVITLINGG-----ESAPTTLTQQTAVP-PPTDLRFTNIGPDTMRV 1376
+ T L G +Y V G +S +P PP L+ ++ D M +
Sbjct: 23519 FKFTRLTEGNEYVFRVAATNRFGIGSYLQSEVIECRSSIRIPGPPETLQIFDVSRDGMTL 23578
Query: 1377 TWAPPPS---IDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVY 1433
TW PP +T ++V V+ + V + + T L G EY V+++
Sbjct: 23579 TWYPPEDDGGSQVTGYIVERKEVRADRWVRVNKVPVTMTRYRSTGLTEGLEYEHRVTAIN 23638
Query: 1434 EQHESTPLR-GRQKTGLD------SPTGIDFSDITANSFTVHWIAPR----ATITGYRIR 1482
+ P R + +D P +D T S ++ W P + +TGY I
Sbjct: 23639 ARGSGKPSRPSKPIVAMDPIAPPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIE 23698
Query: 1483 HHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVP 1542
+ + P TLT+L G EY ++A N G ++VP
Sbjct: 23699 MQKVDQHEWTKCNTTPTKIREYTLTHLPQGAEYRFRVLACNA--------GGPGEPAEVP 23750
Query: 1543 RDLEVVAAT--PTSLLISWDAPAVTVRY---YRITYGETGGNSPVQEFTVPGSKSTATIS 1597
++V P L + VR R+T G P+ ++T G + + +
Sbjct: 23751 GTVKVTEMLEYPDYELDERYQEGIFVRQGGVIRLTIPIKGKPFPICKWTKEG-QDISKRA 23809
Query: 1598 GLKPGVDYTITVYAVTGRGDS---------PASSKPISINYRTEIDKPSQ----MQVTDV 1644
+ +T V RGDS K + I R I P+ ++ D+
Sbjct: 23810 MIATSETHTELVIKEADRGDSGTYDLVLENKCGKKAVYIKVRV-IGSPNSPEGPLEYDDI 23868
Query: 1645 QDNSISVKWLPSS----SPVTGYRVTT--TPKNGPGPTKTKTAGPDQTEMTIEGLQPTVE 1698
Q S+ V W P + + + GY + PK ++ G T + ++GL+ VE
Sbjct: 23869 QVRSVRVSWRPPADDGGADILGYILERREVPKAAWYTIDSRVRG---TSLVVKGLKENVE 23925
Query: 1699 YVVSVYAQNPSGESQPLVQ----TAVTNIDRPKGLA----FTDVDVDSIKIAWESPQGQ- 1749
Y V A+N G S+PL T T ++ P+ + DV S+ ++W P+
Sbjct: 23926 YHFRVSAENQFGISKPLKSEEPVTPKTPLNPPEPPSNPPEVLDVTKSSVSLSWSRPKDDG 23985
Query: 1750 VSRYRVTYSSPEDGIHELFPAPDGEEDTAEL---QGLRPGSEYTVSVVALHD------DM 1800
SR Y ++ + + + + T + GL P +EY ++A +D
Sbjct: 23986 GSRVTGYYIERKETSTDKWVRHNKTQITTTMYTVTGLVPDAEYQFRIIAQNDVGLSETSP 24045
Query: 1801 ESQPLIGTQSTAIPA-PTDLKFTQVTPTSLSAQWTPPNV----QLTGYRVRVTPKEKTGP 1855
S+P++ P+ P +L+ ++ S++ QW P ++ GY V +
Sbjct: 24046 ASEPVVCKDPFDKPSQPGELEILSISKDSVTLQWEKPECDGGKEILGYWVEYRQSGDSAW 24105
Query: 1856 MKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRP---AQGVVTTL-ENVSPPRRA 1911
K + GL+ AT+YE V+A +T SRP A + T L +P R
Sbjct: 24106 KKSNKERIKDKQFTIGGLLEATEYEFRVFAENETGLSRPRRTAMSIKTKLTSGEAPGIRK 24165
Query: 1912 RVTDAT 1917
+ D T
Sbjct: 24166 EMKDVT 24171
Score = 99.8 bits (247), Expect = 3e-20
Identities = 244/1107 (22%), Positives = 422/1107 (38%), Gaps = 171/1107 (15%)
Query: 1092 PPYNTEVTET---TIVITWT-PAPRIGFKLGVRPSQGGEAPREV------TSDSGSIVVS 1141
P N EVTET + + W P G K+ + + R+ ++S V+
Sbjct: 6720 PVRNLEVTETFDGEVSLAWEEPLTDGGSKIIGYVVERRDIKRKTWVLATDRAESCEFTVT 6779
Query: 1142 GLTPG-VEYVYTIQVLR-----DGQERDAPIV--NKVVTPLSPPTNLHLEANPDTGVLTV 1193
GL G VEY++ + + E D P+ +K P PP N+ + GV ++
Sbjct: 6780 GLQKGGVEYLFRVSARNRVGTGEPVETDNPVEARSKYDVP-GPPLNVTITDVNRFGV-SL 6837
Query: 1194 SWERSTTP---DITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYT- 1249
+WE +IT Y I + ++ V A+ S T ++ G EY+ V
Sbjct: 6838 TWEPPEYDGGAEITNYVIELRDKTSIRWDTAM-TVRAEDLSATVTDVVEGQEYSFRVRAQ 6896
Query: 1250 --VKDDKES-----VPISDTIIPEVPQLTDLSFVDITDSSIGLRWTPL---NSSTIIGYR 1299
+ K S V ++D I P + +L+ D T SS+ L+W P S I+GY
Sbjct: 6897 NRIGVGKPSAATPFVKVADPIERPSPPV-NLTSSDQTQSSVQLKWEPPLKDGGSPILGYI 6955
Query: 1300 ITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLT------ 1353
I G+ I + Y VTGLE G Y V G S P+ +
Sbjct: 6956 IERCEEGKDNWIRCNMKLVPELTYKVTGLEKGNKYLYRVSAENKAGVSDPSEILGPLTAD 7015
Query: 1354 ----------------QQTAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVK 1397
+ VP P + + G TW + T V+ +K
Sbjct: 7016 DAFVEPTMDLSAFKDGLEVIVPNPITILVPSTGYPRPTATWCFGDKVLETGDRVK---MK 7072
Query: 1398 NEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHE-STPLRGRQKTGLDSPTGID 1456
AEL ISPS+ + L V ++S + + + P +P +
Sbjct: 7073 TLSAYAELVISPSERSDKGIYTLKLENRVKTISGEIDVNVIARP---------SAPKELK 7123
Query: 1457 FSDITANSFTVHWIAP----RATITGYRIRHHPEHFSGRPREDRVPHSRNSI--TLTNLT 1510
F DIT +S + W P + +TGY + + R +V + T+ +L
Sbjct: 7124 FGDITKDSVHLTWEPPDDDGGSPLTGYVVE---KREVSRKTWTKVMDFVTDLEFTVPDLV 7180
Query: 1511 PGTEYVVSIVALN-------GREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAP- 1562
G EY+ + A N + P+ + +TV D P +++ T S+ ++WD P
Sbjct: 7181 QGKEYLFKVCARNKCGPGEPAYVDEPVNMSTPATVPDPPENVKWRDRTANSIFLTWDPPK 7240
Query: 1563 ---AVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSP 1619
++ Y + G + V P +++ ++GL+ G Y V A+ +G
Sbjct: 7241 NDGGSRIKGYIVERCPRGSDKWV-ACGEPVAETKMEVTGLEEGKWYAYRVKALNRQG--- 7296
Query: 1620 ASSKPISINYRTEIDKPS-QMQVTDVQDNS---ISVKWLPSSSPVTGYRV----TTTPKN 1671
+SKP +P+ ++Q D Q+ + VK L + G ++ T T K
Sbjct: 7297 -ASKP---------SRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKP 7346
Query: 1672 GPGPTKTKT--AGPDQTEMTIEGL--QPTVEYVVS---------VYAQNPSGESQPLVQT 1718
P T TK +TIE + + TV V S + A N G + +V+
Sbjct: 7347 EPKITWTKADMILKQDKRITIENVPKKSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEV 7406
Query: 1719 AVTNIDR---PKGLAFTDVDVDSIKIAWESPQ----GQVSRYRVTYSSPEDGI-HELFPA 1770
V +D+ P TDV +S + W P+ +++ Y V + + + H+L +
Sbjct: 7407 NV--LDKPGPPAAFDITDVTNESCLLTWNPPRDDGGSKITNYVVERRATDSEVWHKL--S 7462
Query: 1771 PDGEEDTAELQGLRPGSEYTVSVVA-----LHDDMESQPLIGTQSTAIPA-PTDLKFTQV 1824
++ + L P EY V A + + +++ P+ P PT L+ + +
Sbjct: 7463 STVKDTNFKATKLIPNKEYIFRVAAENMYGVGEPVQASPITAKYQFDPPGPPTRLEPSDI 7522
Query: 1825 TPTSLSAQWTPPN----VQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYE 1880
T +++ W P+ +TGY V + ++ + ++ V GL KY
Sbjct: 7523 TKDAVTLTWCEPDDDGGSPITGYWVERLDPDTDKWVRCNKMPVKDTTYRVKGLTNKKKYR 7582
Query: 1881 VSVYALKDTLTSRPAQG-----VVTTLENVSPPRRARVTDATETTITISWRTKTE----- 1930
V A +P++ + ++ PP + V D +T++ ++W TK E
Sbjct: 7583 FRVLAENLAGPGKPSKSTEPILIKDPIDPPWPPGKPTVKDVGKTSVRLNW-TKPEHDGGA 7641
Query: 1931 TITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPV---- 1986
I + ++ + ++ + + GL G +Y + +N S P
Sbjct: 7642 KIESYVIEMLKTGTDEWVRVAEGVPTTQHLLPGLMEGQEYSFRVRAVNKAGESEPSEPSD 7701
Query: 1987 VIDASTAIDAPSNLRFLAT---TPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREVV 2039
+ + PS R+L T N+ + W P + IT YI++ + V
Sbjct: 7702 PVLCREKLYPPSPPRWLEVINITKNTADLKWTVPEKDGGSPITNYIVEKRDVRRKGWQTV 7761
Query: 2040 PRPRPGVTEATITGLEPGTEYTIYVIA 2066
T+ T+T L G+ Y V A
Sbjct: 7762 DTTVKD-TKCTVTPLTEGSLYVFRVAA 7787
Score = 99.8 bits (247), Expect = 3e-20
Identities = 292/1340 (21%), Positives = 474/1340 (35%), Gaps = 235/1340 (17%)
Query: 908 PSP-RDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTG 966
P P R+L+ V+V+ + T+ W PPE G + N E + + +T++ T
Sbjct: 11925 PGPVRNLKIVDVSSDRCTVCWDPPEDD-GGCEIQ----NYILEKCETKRMVWSTYS-ATV 11978
Query: 967 LSPGVT---------YYFKVFA-----VSHGRESKPLTAQQTTKLDA-----PTNLQFVN 1007
L+PG T Y F+V A ESKP+ A+ TK D P + V+
Sbjct: 11979 LTPGTTVTRLIEGNEYIFRVRAENKIGTGPPTESKPVIAK--TKYDKPGRPDPPEVTKVS 12036
Query: 1008 ETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSV---SKYPLRNLQPAS 1060
+ + TV+ W PP ITGY L + R V S + ++NL P
Sbjct: 12037 KEEMTVV--WNPPEYDGGKSITGYFLE--KKEKHSTRWVPVNKSAIPERRMKVQNLLPDH 12092
Query: 1061 EYTVSLVAIK----GNQESPKATGVF-TTLQPGSSIPPYNTEVTETT---IVITWTP--- 1109
EY + A G P V ++P PP N V +TT I + W
Sbjct: 12093 EYQFRVKAENEIGIGEPSLPSRPVVAKDPIEPPG--PPTNFRVVDTTKHSITLGWGKPVY 12150
Query: 1110 ---APRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPI 1166
AP IG+ + +RP +P D G + V +T+ L + QE + +
Sbjct: 12151 DGGAPIIGYVVEMRPKIADASP-----DEGWKRCNAAAQLVRKEFTVTSLDENQEYEFRV 12205
Query: 1167 VNKVVTPLSPPTNLHLEANP-----------DTGVLTVSWERSTTPD--ITGYRITTTPT 1213
+ + P L P D + + R+ P R P
Sbjct: 12206 CAQNQVGIGRPAELKEAIKPKEILEPPEIDLDASMRKLVIVRAGCPIRLFAIVRGRPAPK 12265
Query: 1214 NGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDD-------------KESVPIS 1260
+ ++ VV Q +L + + V + +DD +++V ++
Sbjct: 12266 VTWRKVGIDNVVRKGQV-----DLVDTMAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFVN 12320
Query: 1261 DTIIPEVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGYRIT--VVAAGEGIPIFEDFVDS 1318
++ ++DL D+T +S + W P + G ++T +V E V
Sbjct: 12321 VRVLDTPGPVSDLKVSDVTKTSCHVSWAPPENDG--GSQVTHYIVEKREADRKTWSTVTP 12378
Query: 1319 SV--GYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAV-------PPPTDLRFTNI 1369
V + VT L PG +Y V + G PT + + PP L T +
Sbjct: 12379 EVKKTSFHVTNLVPGNEYYFRVTAVNEYGPGVPTDVPKPVLASDPLSEPDPPRKLEVTEM 12438
Query: 1370 GPDTMRVTWAPP---PSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYV 1426
++ + W PP + ++ Y + D D ++V+T L G +Y
Sbjct: 12439 TKNSATLAWLPPLRDGGAKIDGYITSYREEEQPADRWTEYSVVKDLSLVVTGLKEGKKYK 12498
Query: 1427 VSVSSVYEQHESTPLRG----RQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIR 1482
V++ S P K L P + IT + G ++R
Sbjct: 12499 FRVAARNAVGVSLPREAEGVYEAKEQLLPPKILMPEQITIKA-------------GKKLR 12545
Query: 1483 HHPEHFSGRPR--------EDRV----------PHSRNSITLTNLTPGTEYVVSIVALNG 1524
H G+P ED V S + + + ++T S+ A N
Sbjct: 12546 IE-AHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGYYSLTAENS 12604
Query: 1525 ----REESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAP----AVTVRYYRITYGET 1576
++ +++ P D+ + A SL SW P + Y + +
Sbjct: 12605 SGTDTQKIKVVVMDAPGPPQPPFDISDIDADACSL--SWHIPLEDGGSNITNYIVEKCDV 12662
Query: 1577 GGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDS-PASSKPISINYRTEI-D 1634
V +K++ + L PG +Y V A G S P +S + + +
Sbjct: 12663 SRGDWVTAL-ASVTKTSCRVGKLIPGQEYIFRVRAENRFGISEPLTSPKMVAQFPFGVPS 12721
Query: 1635 KPSQMQVTDVQDNSISVKW-LPSS---SPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTI 1690
+P +VT V + I V W P S SP+ GY + +N K TE
Sbjct: 12722 EPKNARVTKVNKDCIFVAWDRPDSDGGSPIIGYLIERKERNSLLWVKANDTLVRSTEYPC 12781
Query: 1691 EGLQPTVEYVVSVYAQNPSGESQPL----VQTAVTNIDRPKGLAFTDVDVDSIKIAWESP 1746
GL +EY +YA N +G S P TA +D P DV ++ + W P
Sbjct: 12782 AGLVEGLEYSFRIYALNKAGSSPPSKPTEYVTARMPVDPPGKPEVIDVTKSTVSLIWARP 12841
Query: 1747 QGQVSRYRVTY-----SSPEDGIHELFPAP---DGEEDTAELQGLRPGSEYTVSVVALHD 1798
+ + Y P D AP EE TA GL ++Y +A
Sbjct: 12842 KHDGGSKIIGYFVEACKLPGDKWVRCNTAPHQIPQEEYTA--TGLEEKAQYQFRAIARTA 12899
Query: 1799 DMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLT-GYRVRVTPKEKTG--- 1854
S P P+D P ++ A+ PP + L+ + +T K T
Sbjct: 12900 VNISPP---------SEPSD-------PVTILAENVPPRIDLSVAMKSLLTVKAGTNVCL 12943
Query: 1855 -------PMKEINLAPDSSSV-VVSGLMVATKYEVSVYAL-----KD----TLTSRPAQG 1897
PM ++ D + + G+ +A + + L KD T+T+ + G
Sbjct: 12944 DATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTITAENSSG 13003
Query: 1898 ------VVTTLENVSPPRRARVTDATETTITISWRTKTE----TITGFQVDAVPANGQTP 1947
+ L+ PP ++ +SW E IT + VD +
Sbjct: 13004 SKSATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYIVDKRETSRPNW 13063
Query: 1948 IQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVID---ASTAIDAPSNLR--- 2001
Q + + S ++ L G +Y+ + N PV + A D P
Sbjct: 13064 AQVSATVPITSCSVEKLIEGHEYQFRICAENKYGVGDPVFTEPAIAKNPYDPPGRCDPPV 13123
Query: 2002 FLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREVVPRPRPGVTEATI--TGLE 2055
T + + VSW+PP + ITGY++ EK + R + E T+ TGL+
Sbjct: 13124 ISNITKDHMTVSWKPPADDGGSPITGYLL--EKRETQAVNWTKVNRKPIIERTLKATGLQ 13181
Query: 2056 PGTEYTIYVIALKNNQKSEP 2075
GTEY V A+ +P
Sbjct: 13182 EGTEYEFRVTAINKAGPGKP 13201
Score = 98.6 bits (244), Expect = 7e-20
Identities = 157/730 (21%), Positives = 276/730 (37%), Gaps = 78/730 (10%)
Query: 785 KYIVNVYQISEDGEQSLIL-----STSQTTAP---DAPPDPT----VDQVDDTSIVVRWS 832
K + I + GE +L L +TS+T D P PT +D++D TSI + W
Sbjct: 23423 KLTIRETTIRDTGEYTLELKNVTGTTSETIKVIILDKPGPPTGPIKIDEIDATSITISWE 23482
Query: 833 RPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQE 888
P+ AP++GY + + ++ T ++ + L G +Y + A N+
Sbjct: 23483 PPELDGGAPLSGYVVEQRDAHRPGWLPVSESVTRSTFKFTRLTEGNEYVFRVAAT--NRF 23540
Query: 889 STPVVIQQETTGTPRSDTVPSPRD-LQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIP 943
+Q E S +P P + LQ +V+ +T+ W PPE S VTGY V+
Sbjct: 23541 GIGSYLQSEVIECRSSIRIPGPPETLQIFDVSRDGMTLTWYPPEDDGGSQVTGYIVERKE 23600
Query: 944 VNLPG-EHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSH------GRESKPLTAQQTTK 996
V ++P++ + TGL+ G+ Y +V A++ R SKP+ A
Sbjct: 23601 VRADRWVRVNKVPVTMTRYRS-TGLTEGLEYEHRVTAINARGSGKPSRPSKPIVAMDPIA 23659
Query: 997 LDA-PTNLQFVNETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPS-VSK 1050
P N + + T ++V + W+ P +++TGY + + + + + N P+ + +
Sbjct: 23660 PPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTKCNTTPTKIRE 23719
Query: 1051 YPLRNLQPASEYTVSLVAIK-GNQESPKATGVFTTLQPGSSIPPYNTE--------VTET 1101
Y L +L +EY ++A G P + P Y + V +
Sbjct: 23720 YTLTHLPQGAEYRFRVLACNAGGPGEPAEVPGTVKVTEMLEYPDYELDERYQEGIFVRQG 23779
Query: 1102 TIVITWTPAPRIGFKLGVRPSQGGEAPREV---TSDSGS-IVVSGLTPGVEYVYTIQVLR 1157
++ P F + +G + + TS++ + +V+ G Y + +
Sbjct: 23780 GVIRLTIPIKGKPFPICKWTKEGQDISKRAMIATSETHTELVIKEADRGDSGTYDLVLEN 23839
Query: 1158 DGQERDAPIVNKVV-TPLSPPTNLHLEANPDTGVLTVSWERSTTP---DITGYRITTTPT 1213
++ I +V+ +P SP L + + + VSW DI GY +
Sbjct: 23840 KCGKKAVYIKVRVIGSPNSPEGPLEYD-DIQVRSVRVSWRPPADDGGADILGYILERREV 23898
Query: 1214 NGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKD--------DKESVPISDTIIP 1265
+++ V +S L +EY+ V +E V + P
Sbjct: 23899 PKAAWYTIDSRVRG--TSLVVKGLKENVEYHFRVSAENQFGISKPLKSEEPVTPKTPLNP 23956
Query: 1266 EVPQLTDLSFVDITDSSIGLRWT---PLNSSTIIGYRITVVAAGEGIPIFEDFVDSSVGY 1322
P +D+T SS+ L W+ S + GY I + + +
Sbjct: 23957 PEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRVTGYYIERKETSTDKWVRHNKTQITTTM 24016
Query: 1323 YTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAVPPPTD-------LRFTNIGPDTMR 1375
YTVTGL P +Y +I + G S + ++ P D L +I D++
Sbjct: 24017 YTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCKDPFDKPSQPGELEILSISKDSVT 24076
Query: 1376 VTWAPPP---SIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSV 1432
+ W P ++ + V Y + D + LL TEY V +
Sbjct: 24077 LQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERIKDKQFTIGGLLEATEYEFRVFAE 24136
Query: 1433 YEQHESTPLR 1442
E S P R
Sbjct: 24137 NETGLSRPRR 24146
Score = 96.3 bits (238), Expect = 3e-19
Identities = 294/1454 (20%), Positives = 518/1454 (35%), Gaps = 209/1454 (14%)
Query: 684 IQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSA 743
I+ G Q + + + S P+T + P PL VT +TA ++W
Sbjct: 18400 IRTDGGQYILKLSNVGGTKSIPITVKVLDRPGPPEGPL-----KVTGVTAEKCYLAWNPP 18454
Query: 744 SDTVSGFRVEYELSEEGDEPQYLDLPSTATSVN-----IPDLLPGRKYI-----VNVYQI 793
G + + + E+ E L +T V + LLPG +YI VN Y I
Sbjct: 18455 LQD-GGANISHYIIEKR-ETSRLSWTQVSTEVQALNYKVTKLLPGNEYIFRVMAVNKYGI 18512
Query: 794 SEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRP----QAPITGYRIVYSPSV 849
E E + + + P P P V + S+VV W+RP I GY I+
Sbjct: 18513 GEPLESGPVTACNPYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGY-ILEKRDK 18571
Query: 850 EGSSTELNLPETANSVTL--SDLQPGVQYNITIYAVEE---NQESTPVVIQQETTGTPRS 904
EG +T + L + L G Y + A + S P V +
Sbjct: 18572 EGVRWTKCNKKTLTDLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYR------AC 18625
Query: 905 DTVPSPRDLQFVEVTDV---KVTIMWTPP----ESAVTGYRVDV------------IPVN 945
D + P +VTD V++ W+ P + V GY V+V P
Sbjct: 18626 DALYPPGPPSNPKVTDTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAADEWTTCTPPTG 18685
Query: 946 LPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLT------AQQ-----T 994
L G+ VT L Y F++ A++ +P T AQ+
Sbjct: 18686 LQGKQ-----------FTVTKLKENTEYNFRICAINSEGVGEPATLPGSVVAQERIEPPE 18734
Query: 995 TKLDAPTNLQFVNETDSTVLVRWT---PPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKY 1051
+LDA V +T+ + T P ++ + LT R Q V S +
Sbjct: 18735 IELDADLRKVVVLRASATLRLFVTIKGRPEPEVKWEKAEGILTDRA---QIEVTSSFTML 18791
Query: 1052 PLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAP 1111
+ N+ +L + V P + + EV + ++ ++W P
Sbjct: 18792 VIDNVTRFDSGRYNLTLENNSGSKTAFVNVRVLDSPSAPVNLTIREVKKDSVTLSWEPPL 18851
Query: 1112 RIGFKLGVRPSQGGEAPREVTSDSGSIV----------VSGLTPGVEYVYTIQVLRD--- 1158
G G + + RE T + + + + L G Y + + +
Sbjct: 18852 IDG---GAKITNYIVEKRETTRKAYATITNNCTKTTFRIENLQEGCSYYFRVLASNEYGI 18908
Query: 1159 GQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT---PDITGYRITTTPTNG 1215
G + KV P PP + L + T+ WE+ + ITGY +
Sbjct: 18909 GLPAETTEPVKVSEPPLPPGRVTL-VDVTRNTATIKWEKPESDGGSKITGYVVEMQTKGS 18967
Query: 1216 QQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPEVPQLTDLSF 1275
++ ++ +V + T L+ G EY V V + S P +P + + ++
Sbjct: 18968 EKWSTCTQVKTLE---ATISGLTAGEEYVFRVAAVNEKGRSDP-RQLGVPVIARDIEIK- 19022
Query: 1276 VDITDSSIGLRWTPLNSSTIIGYRITVVAAG----------EGIPIFEDFVDSSVGYYTV 1325
S+ L + N +I V G +G + E + TV
Sbjct: 19023 -----PSVELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTV 19077
Query: 1326 TGL--EPGIDYDISVITLI----NGGESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTWA 1379
T L + D+ L G + P T+ PP +R + D++ ++W
Sbjct: 19078 TSLSIKEASKEDVGTYELCVSNSAGSITVPITIIVLDRPGPPGPIRIDEVSCDSITISWN 19137
Query: 1380 PPP---SIDLTNFLVRYSPVKNEEDVAE---LSISPSDNAVVLTNLLPGTEYVVSVSS-- 1431
PP ++N++V K E +S + + ++ + L G+EY V +
Sbjct: 19138 PPEYDGGCQISNYIVE----KKETTSTTWHIVSQAVARTSIKIVRLTTGSEYQFRVCAEN 19193
Query: 1432 ---VYEQHESTPLRGRQKTGLDSPTGI-DFSDITANSFTVHWIAP----RATITGYRIRH 1483
ES+ + P G T ++ V W P + + GY + +
Sbjct: 19194 RYGKSSYSESSAVVAEYPFSPPGPPGTPKVVHATKSTMLVTWQVPVNDGGSRVIGYHLEY 19253
Query: 1484 HPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN----GREESPLLIGQQSTVS 1539
+ +++ + + ++ L G Y + A N G+
Sbjct: 19254 KERSSILWSKANKILIADTQMKVSGLDEGLMYEYRVYAENIAGIGKCSKSCEPVPARDPC 19313
Query: 1540 DVPRDLEVVAATPTSLLISWDAP----AVTVRYYRITYGETGGNSPVQEFTVPGSKSTAT 1595
D P EV T S+ + W P + Y + E ++ ++
Sbjct: 19314 DPPGQPEVTNITRKSVSLKWSKPHYDGGAKITGYIVERRELPDGRWLKCNYTNIQETYFE 19373
Query: 1596 ISGLKPGVDYTITVYAVTGRGD-SPASSKPISINYRTEIDKPSQMQVTDVQDNSI--SVK 1652
++ L Y V+A S S I + +++ P M +D + + +
Sbjct: 19374 VTELTEDQRYEFRVFARNAADSVSEPSESTGPIIVKDDVEPPRVMMDVKFRDVIVVKAGE 19433
Query: 1653 WLPSSSPVTG--YRVTTTPKNG---PGPTKTKTAGPD-QTEMTIEGL--QPTVEYVVSVY 1704
L ++ + G V + K+G +T+ D T +T++ + T +YV+++
Sbjct: 19434 VLKINADIAGRPLPVISWAKDGIEIEERARTEIISTDNHTLLTVKDCIRRDTGQYVLTL- 19492
Query: 1705 AQNPSGESQPLVQTAVTNIDRPKG--LAFTDVDVDSIKIAWESPQ----GQVSRYRVTYS 1758
+N +G V V + P L + + ++W PQ + Y V
Sbjct: 19493 -KNVAGTRSVAVNCKVLDKPGPPAGPLEINGLTAEKCSLSWGRPQEDGGADIDYYIV--- 19548
Query: 1759 SPEDGIHELFPAPDGE--EDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPA- 1815
+ H + +GE + ++ L G+EY V ++ +PL +S AI A
Sbjct: 19549 EKRETSHLAWTICEGELQMTSCKVTKLLKGNEYIFRVTGVNKYGVGEPL---ESVAIKAL 19605
Query: 1816 --------PTDLKFTQVTPTSLSAQWTPP----NVQLTGYRVRVTPKEKTGPMKEINLAP 1863
PT L+ T VT S++ W+ P +++GY + K ++
Sbjct: 19606 DPFTVPSPPTSLEITSVTKESMTLCWSRPESDGGSEISGYIIERREKNSLRWVRVNKKPV 19665
Query: 1864 DSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQ--GVVTTLENV---SPPRRARVTDATE 1918
V +GL +YE VYA S P++ ++ + V SPP + ++ D+ +
Sbjct: 19666 YDLRVKSTGLREGCEYEYRVYAENAAGLSLPSETSPLIRAEDPVFLPSPPSKPKIVDSGK 19725
Query: 1919 TTITISWRTKT----ETITGFQVD---AVPANGQTPIQRTIKPDVRSYTITGLQPGTDYK 1971
TTITI+W ITG+ V+ + + +T IQ + YTI+GL G +Y
Sbjct: 19726 TTITIAWVKPLFDGGAPITGYTVEYKKSDDTDWKTSIQSLRGTE---YTISGLTTGAEYV 19782
Query: 1972 IYLYTLNDNARSSP 1985
+ ++N S P
Sbjct: 19783 FRVKSVNKVGASDP 19796
Score = 95.5 bits (236), Expect = 6e-19
Identities = 319/1473 (21%), Positives = 540/1473 (36%), Gaps = 232/1473 (15%)
Query: 777 IPDLLPGRKYIVNVYQISEDG--EQSLILSTSQTTAPDAPPD------PTVDQVDDTSIV 828
+ DL+ G +Y V ++ G + S + PD PP V++ + +IV
Sbjct: 9706 VEDLVEGGEYEFRVKAVNAAGVSKPSATVGPCDCQRPDMPPSIDLKEFMEVEEGTNVNIV 9765
Query: 829 VR----------WSR--PQAPITGYRIVYSPSVE----GSSTELNLPETANSVTLSDLQP 872
+ W + P+ P ++Y V + L +P++ S T
Sbjct: 9766 AKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDT------ 9819
Query: 873 GVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE- 931
G+ TI AV N + ++ G P P ++F V+ ++T+ W PP+
Sbjct: 9820 GLY---TITAVN-NLGTASKEMRLNVLGRPGPPVGP----IKFESVSADQMTLSWFPPKD 9871
Query: 932 ---SAVTGYRVDVIPVNLPG-EHGQRLPISRNTFAEVTGLSPGVTYYFKVFA-----VSH 982
S +T Y ++ N H P + + L G Y F++ A +
Sbjct: 9872 DGGSKITNYVIEKREANRKTWVHVSSEP--KECTYTIPKLLEGHEYVFRIMAQNKYGIGE 9929
Query: 983 GRESKPLTAQQTTKLD-APTNLQFVNETDSTVLVRWTPPR----AQITGYRLTVGLTRRG 1037
+S+P TA+ + AP + T +++ V W P + +TGY L + T
Sbjct: 9930 PLDSEPETARNLFSVPGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPVTGYWLEMKDTTSK 9989
Query: 1038 QPRQYNVGPSVS-----KYPLRNLQPASEYTVSLVAIKGNQESPK------ATGVFTTLQ 1086
+ ++ N P + Y + L S+Y + AI P AT
Sbjct: 9990 RWKRVNRDPIKAMTLGVSYKVTGLIEGSDYQFRVYAINAAGVGPASLPSDPATARDPIAP 10049
Query: 1087 PGSSIPPYNTEVTETTIVITWTPAPRIGFKLG----VRPSQGGEAPREVTSDSG----SI 1138
PG P T+ T+++ + W+P + G V + G+ E D +
Sbjct: 10050 PGPPFPKV-TDWTKSSADLEWSPPLKDGGSKVTGYIVEYKEEGKEEWEKGKDKEVRGTKL 10108
Query: 1139 VVSGLTPGVEYVYTIQVLRD---GQERDAPIVNKVVTPLSPPTNLHLEANP-DTGVLTVS 1194
VV+GL G Y + ++ + G+ + V ++ L P +L L+A+ D V+
Sbjct: 10109 VVTGLKEGAFYKFRVRAVNIAGIGEPGEVTDVIEMKDRLVSP-DLQLDASVRDRIVVHAG 10167
Query: 1195 WERSTTPDITGYRITTTPTNGQQGNSLEEVV---HADQSSCTFDNLSPGLEYNVSVYTVK 1251
++G T N + +E A SS N + VY++
Sbjct: 10168 GVIRIIAYVSGKPPPTVTWNMNERTLPQEATIETTAISSSMVIKNCQRSHQ---GVYSLL 10224
Query: 1252 DDKESVPISDTIIPEV-----PQLTDLSFVDITDSSIGLRW-TPLNS--STIIGYRITVV 1303
E+ TII +V P T ++T+ S L W +P + S I Y I
Sbjct: 10225 AKNEAGERKKTIIVDVLDVPGPVGTPFLAHNLTNESCKLTWFSPEDDGGSPITNYVIEKR 10284
Query: 1304 AAGEGI--PIFEDFVDSSVGYYTVTGLEPGIDY--DISVITLINGGESAPTT----LTQQ 1355
+ P+ + TV GL G Y I+ I G T+ + +
Sbjct: 10285 ESDRRAWTPVTYTVTRQNA---TVQGLIQGKAYFFRIAAENSIGMGPFVETSEALVIREP 10341
Query: 1356 TAVPP-PTDLRFTNIGPDTMRVTWAPPP---SIDLTNFLVRYSPVKNEEDVAELSISPSD 1411
VP P DL + +T+ +TW PP ++ N+++ + E+ + +
Sbjct: 10342 ITVPERPEDLEVKEVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEKFHKVTNDNLLS 10401
Query: 1412 NAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQ----KTGLDSPT-GIDFSDITANSFT 1466
+ L G Y VS+V + P + K L PT +DF D T
Sbjct: 10402 RKYTVKGLKEGDTYEYRVSAVNIVGQGKPSFCTKPITCKDELAPPTLHLDFRD----KLT 10457
Query: 1467 VHWIAPRATITGYRIRHHPEHFSGRPR------EDRVPHSRNSITLTNLTPGTEYVVSIV 1520
+ + +TG +SG+P+ +D + T TP T + I
Sbjct: 10458 IR-VGEAFALTG--------RYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATLALEKIK 10508
Query: 1521 ALNGREESPLLIGQQST--------VSDVPRDLEVVA------ATPTSLLISWDAP---- 1562
A ++ + ST V+ V R V T ++ISW P
Sbjct: 10509 AKRSDSGKYCVVVENSTGSRKGFCQVNVVDRPGPPVGPVSFDEVTKDYMVISWKPPLDDG 10568
Query: 1563 AVTVRYYRITYGETGGN--SPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDS-P 1619
+ Y I E G + PV T +K+T +S L G DY ++A G S P
Sbjct: 10569 GSKITNYIIEKKEVGKDVWMPV---TSASAKTTCKVSKLLEGKDYIFRIHAENLYGISDP 10625
Query: 1620 ASSKPISINYRTEI-DKPSQMQVTDVQDNSISVKWLP---SSSPVTGY---RVTTTPKNG 1672
S + R + D P Q VT+V +S V W P+T Y + T K
Sbjct: 10626 LVSDSMKAKDRFRVPDAPDQPIVTEVTKDSALVTWNKPHDGGKPITNYILEKRETMSKRW 10685
Query: 1673 PGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQN------PSGESQPL-VQTAVTNIDR 1725
TK T+ + L +Y V A+N PS S+P+ + +
Sbjct: 10686 ARVTKDPIH--PYTKFRVPDLLEGCQYEFRVSAENEIGIGDPSPPSKPVFAKDPIAKPSP 10743
Query: 1726 PKGLAFTDVDVDSIKIAWESPQ----GQVSRYRVTYSSPEDGI-HELFPAPDGEEDTA-E 1779
P D +S+ + W+ P+ ++ Y V Y D P+ +T +
Sbjct: 10744 PVNPEAIDTTCNSVDLTWQPPRHDGGSKILGYIVEYQKVGDEEWRRANHTPESCPETKYK 10803
Query: 1780 LQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTS-LSAQWTPPNV 1838
+ GLR G Y V+A++ ES P +P P +K P L A
Sbjct: 10804 VTGLRDGQTYKFRVLAVNAAGESDP------AHVPEPVLVKDRLEPPELILDANMAREQH 10857
Query: 1839 QLTGYRVRVT------PKEKTGPMKEINLAPDSSSVVVSGLMVATKYEV--------SVY 1884
G +R++ P K KE AP + + V+ V +K E+ +Y
Sbjct: 10858 IKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARIDVTP--VGSKLEIRNAAHEDGGIY 10915
Query: 1885 AL--KDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTE----TITGFQVD 1938
+L ++ S+ V L+ PPR V++ + + ++W+ + IT + V+
Sbjct: 10916 SLTVENPAGSKTVSVKVLVLDKPGPPRDLEVSEIRKDSCYLTWKEPLDDGGSVITNYVVE 10975
Query: 1939 A--VPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPV-------VID 1989
V + +P+ T K +S+ L G Y + N R V +D
Sbjct: 10976 RRDVASAQWSPLSATSKK--KSHFAKHLNEGNQYLFRVAAENQYGRGPFVETPKPIKALD 11033
Query: 1990 ASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREVVPRPRPG 2045
P +L + + + W P + ITGY+++Y++ G+ ++ +
Sbjct: 11034 PLHPPGPPKDLHHVDVDKTEVSLVWNKPDRDGGSPITGYLVEYQEEGT--QDWIKFKTVT 11091
Query: 2046 VTEATITGLEPGTEYTIYVIALKNNQKSEPLIG 2078
E +TGL+ G Y V K+E ++G
Sbjct: 11092 NLECVVTGLQQGKTYRFRV-------KAENIVG 11117
Score = 95.1 bits (235), Expect = 7e-19
Identities = 312/1572 (19%), Positives = 569/1572 (36%), Gaps = 228/1572 (14%)
Query: 616 ITETPSQPNSHPIQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLK 672
+T T S + W P+ S + Y++ +PK + +W N+ + GL
Sbjct: 17847 VTLTDVSQTSASLMWEKPEHDGGSRVLGYVVEMQPKGTE-KWSIVAESKVCNA-VVTGLS 17904
Query: 673 PGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETT---PFSP--LVATSES 727
G Y+ ++ + + G + PV + +T + + PF+ + A +
Sbjct: 17905 SGQEYQFRVKAYNEKGKSD-------PRVLGVPVIAKDLTIQPSLKLPFNTYSIQAGEDL 17957
Query: 728 VTEITASSFV---VSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGR 784
EI +SWV + + + +++ TATS + + G
Sbjct: 17958 KIEIPVIGRPRPNISWVKDGEPLK-------------QTTRVNVEETATST-VLHIKEGN 18003
Query: 785 KYIVNVYQISED---GEQSLILSTSQTTAPDAPPDPT-VDQVDDTSIVVRWSRPQ----A 836
K Y ++ G + LS P P P D+V +V+ W P
Sbjct: 18004 KDDFGKYTVTATNSAGTATENLSVIVLEKPGPPVGPVRFDEVSADFVVISWEPPAYTGGC 18063
Query: 837 PITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQ 896
I+ Y + + + ++ ++ ++ L+ G +Y I+A +S P+ +
Sbjct: 18064 QISNYIVEKRDTTTTTWHMVSATVARTTIKITKLKTGTEYQFRIFAENRYGKSAPLDSKA 18123
Query: 897 ETTGTPRSDTVPSPRDLQFV-EVTDVKVTIMWTPPES----AVTGYRVDVIPVN-LPGEH 950
P + P P FV ++ ++ + W P + + GY ++ N +
Sbjct: 18124 VIVQYPFKE--PGPPGTPFVTSISKDQMLVQWHEPVNDGGTKIIGYHLEQKEKNSILWVK 18181
Query: 951 GQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQT----TKLDAPTNLQFV 1006
+ PI F + TGL G+ Y FKV A + KP + D P + +
Sbjct: 18182 LNKTPIQDTKF-KTTGLDEGLEYEFKVSAENIVGIGKPSKVSECFVARDPCDPPGRPEAI 18240
Query: 1007 NETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSV-SKYPLRNLQPASE 1061
T + V ++W P ++ITGY + G+ + + + +++ + L
Sbjct: 18241 VITRNNVTLKWKKPAYDGGSKITGYIVEKKDLPDGRWMKASFTNVLETEFTVSGLVEDQR 18300
Query: 1062 YTVSLVA--IKGNQESPK-ATGVFTTLQ----PGSSIPPYNTEVT-----ETTIV---IT 1106
Y ++A GN P ++G T P +S+ P +V ET ++ I
Sbjct: 18301 YEFRVIARNAAGNFSEPSDSSGAITARDEIDAPNASLDPKYKDVIVVHAGETFVLEADIR 18360
Query: 1107 WTPAPRIGFKLGVRPSQGGEAPREVTS--DSGSIVVSGL--TPGVEYVYTIQVLRDGQER 1162
P P + + + + A E+ S ++VV T G +Y+ +++ G +
Sbjct: 18361 GKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQYI--LKLSNVGGTK 18418
Query: 1163 DAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWE---RSTTPDITGYRITTTPTNGQQGN 1219
PI KV+ PP ++W + +I+ Y I T+
Sbjct: 18419 SIPITVKVLDRPGPPEGPLKVTGVTAEKCYLAWNPPLQDGGANISHYIIEKRETSRLSWT 18478
Query: 1220 SLEEVVHADQSSCTFDNLSPGLEY-----NVSVYTVKDDKESVPIS---------DTIIP 1265
+ V A T L PG EY V+ Y + + ES P++ P
Sbjct: 18479 QVSTEVQALNYKVT--KLLPGNEYIFRVMAVNKYGIGEPLESGPVTACNPYKPPGPPSTP 18536
Query: 1266 EVPQLTDLSFV-----DITDSSI-------------GLRWTPLNSSTIIGYRITVVAAGE 1307
EV +T S V + D G+RWT N T+ R+ V E
Sbjct: 18537 EVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDKEGVRWTKCNKKTLTDLRLRVTGLTE 18596
Query: 1308 GIPI-FEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAVPPPTDLRF 1366
G F +++ G + EP + Y G PP++ +
Sbjct: 18597 GHSYEFRVAAENAAGVGEPS--EPSVFYRACDALYPPG---------------PPSNPKV 18639
Query: 1367 TNIGPDTMRVTWAPP---PSIDLTNFLVRYSPVKNEE-DVAELSISPSDNAVVLTNLLPG 1422
T+ ++ + W+ P + ++V +E +T L
Sbjct: 18640 TDTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAADEWTTCTPPTGLQGKQFTVTKLKEN 18699
Query: 1423 TEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGY-RI 1481
TEY + ++ + P ++ A+ V + AT+ + I
Sbjct: 18700 TEYNFRICAINSEGVGEPATLPGSVVAQERIEPPEIELDADLRKVVVLRASATLRLFVTI 18759
Query: 1482 RHHPEHFSGRPREDRVPHSRNSITLT---------NLTPGTEYVVSIVALNGREESPLLI 1532
+ PE + + + R I +T N+T ++ N +
Sbjct: 18760 KGRPEPEVKWEKAEGILTDRAQIEVTSSFTMLVIDNVTRFDSGRYNLTLENNSGSKTAFV 18819
Query: 1533 GQQSTVS-DVPRDLEVVAATPTSLLISWDAPAVT----VRYYRITYGETGGNSPVQEFTV 1587
+ S P +L + S+ +SW+ P + + Y + ET + T
Sbjct: 18820 NVRVLDSPSAPVNLTIREVKKDSVTLSWEPPLIDGGAKITNYIVEKRETTRKA-YATITN 18878
Query: 1588 PGSKSTATISGLKPGVDYTITVYAVT--GRGDSPASSKPISINYRTEIDKPSQMQVTDVQ 1645
+K+T I L+ G Y V A G G +++P+ ++ P ++ + DV
Sbjct: 18879 NCTKTTFRIENLQEGCSYYFRVLASNEYGIGLPAETTEPVKVSEPPL--PPGRVTLVDVT 18936
Query: 1646 DNSISVKW-LPSS---SPVTGYRVTTTPKNGPGPTKTKTAGPDQT-EMTIEGLQPTVEYV 1700
N+ ++KW P S S +TGY V K G K T +T E TI GL EYV
Sbjct: 18937 RNTATIKWEKPESDGGSKITGYVVEMQTK---GSEKWSTCTQVKTLEATISGLTAGEEYV 18993
Query: 1701 VSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVD-SIKIAWESPQGQVSRYRVTYSS 1759
V A N G S P Q V I R D+++ S+++ + + + +R ++
Sbjct: 18994 FRVAAVNEKGRSDPR-QLGVPVIAR-------DIEIKPSVELPFHTFNVK-AREQLKIDV 19044
Query: 1760 PEDGIHELFP--APDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQ-------- 1809
P G + DG+ E + S TV+ +++ + S+ +GT
Sbjct: 19045 PFKGRPQATVNWRKDGQT-LKETTRVNVSSSKTVTSLSIKE--ASKEDVGTYELCVSNSA 19101
Query: 1810 -STAIPA----------PTDLKFTQVTPTSLSAQWTPPNV----QLTGYRVRVTPKEKTG 1854
S +P P ++ +V+ S++ W PP Q++ Y V KE T
Sbjct: 19102 GSITVPITIIVLDRPGPPGPIRIDEVSCDSITISWNPPEYDGGCQISNYIVE--KKETTS 19159
Query: 1855 PMKEI-NLAPDSSSVVVSGLMVATKYEVSVYAL----KDTLTSRPAQGVVTTLENVSPPR 1909
I + A +S+ + L ++Y+ V A K + + A PP
Sbjct: 19160 TTWHIVSQAVARTSIKIVRLTTGSEYQFRVCAENRYGKSSYSESSAVVAEYPFSPPGPPG 19219
Query: 1910 RARVTDATETTITISWRTKT----ETITGFQVDAVPANG--QTPIQRTIKPDVRSYTITG 1963
+V AT++T+ ++W+ + G+ ++ + + + + D + ++G
Sbjct: 19220 TPKVVHATKSTMLVTWQVPVNDGGSRVIGYHLEYKERSSILWSKANKILIADTQ-MKVSG 19278
Query: 1964 LQPGTDYKIYLYTLN----DNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPR- 2018
L G Y+ +Y N S + A D P T S+ + W P
Sbjct: 19279 LDEGLMYEYRVYAENIAGIGKCSKSCEPVPARDPCDPPGQPEVTNITRKSVSLKWSKPHY 19338
Query: 2019 ---ARITGYIIK 2027
A+ITGYI++
Sbjct: 19339 DGGAKITGYIVE 19350
Score = 94.7 bits (234), Expect = 1e-18
Identities = 315/1607 (19%), Positives = 572/1607 (35%), Gaps = 282/1607 (17%)
Query: 628 IQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISI 684
+ W P+ + I Y++ K W + + GL G Y ++ ++
Sbjct: 7630 LNWTKPEHDGGAKIESYVIEML-KTGTDEWVRVAEGVPTTQHLLPGLMEGQEYSFRVRAV 7688
Query: 685 QQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSAS 744
+ G E + S+ V + P V IT ++ + W +
Sbjct: 7689 NKAGESEPSE------------PSDPVLCREKLYPPSPPRWLEVINITKNTADLKW-TVP 7735
Query: 745 DTVSGFRVEYELSEEGDEP----QYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGE-- 798
+ G + + E+ D Q +D T + L G Y+ V + G+
Sbjct: 7736 EKDGGSPITNYIVEKRDVRRKGWQTVDTTVKDTKCTVTPLTEGSLYVFRVAAENAIGQSD 7795
Query: 799 ----QSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ----APITGYRIVYSPSVE 850
+ +L+ T P P V V + ++W P+ PI Y I +
Sbjct: 7796 YTEIEDSVLAKDTFTTPGPPYALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKERL- 7854
Query: 851 GSSTELNLPETAN---SVTLSDLQPGVQYNITIYAVEEN-----QESTPVVIQQETTGTP 902
+ + +TA + ++D+ G + + A E E T ++ ++ T P
Sbjct: 7855 -GTRWVKAGKTAGPDCNFRVTDVIEGTEVQFQVRAENEAGVGHPSEPTEILSIEDPTSPP 7913
Query: 903 RSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPVNLPGEHGQRL---P 955
P DL + + I W PPE S + GY V++ PV E R+ P
Sbjct: 7914 SP-----PLDLHVTDAGRKHIAIAWKPPEKNGGSPIIGYHVEMCPVGT--EKWMRVNSRP 7966
Query: 956 ISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLV 1015
I F G+ P Y +V AV+ S+P + P ++ ++V
Sbjct: 7967 IKDLKFKVEEGVVPDKEYVLRVRAVNAIGVSEPSEISENVVAKDPDCKPTIDLETHDIIV 8026
Query: 1016 RWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPL-RNLQPASEYTVSLVAIKGNQE 1074
I G +L++ + R P P+VS + + ++ + T+ I + E
Sbjct: 8027 --------IEGEKLSIPVPFRAVPV-----PTVSWHKDGKEVKASDRLTMKNDHISAHLE 8073
Query: 1075 SPKAT----GVFT-TLQP--GSSIPPYN---------------TEVTETTIVITWTP--- 1109
PK+ G++T TL+ GS+ N +++T+++ +TW P
Sbjct: 8074 VPKSVRADAGIYTITLENKLGSATASINVKVIGLPGPCKDIKASDITKSSCKLTWEPPEF 8133
Query: 1110 ---APRIGFKLGVRPSQGGEAPREVTSDSGSI--VVSGLTPGVEYVYTIQVLRD-GQERD 1163
P + + L R + G V S + V L P EY + ++ + G
Sbjct: 8134 DGGTPILHYVLERREA-GRRTYIPVMSGENKLSWTVKDLIPNGEYFFRVKAVNKVGGGEY 8192
Query: 1164 APIVNKVVT-----PLSPPTNLHLEANPDTGVLTVSWERSTTPD---ITGYRITTTPTNG 1215
+ N V+ P PP ++ + NP +T++W+ I GY I
Sbjct: 8193 IELKNPVIAQDPKQPPDPPVDVEVH-NPTAEAMTITWKPPLYDGGSKIMGYIIEKIAKGE 8251
Query: 1216 QQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYT-----VKDDKESVPISDTIIP-EVPQ 1269
++ E + + T L G EY V + + + P + + P + P+
Sbjct: 8252 ERWKRCNEHL-VPILTYTAKGLEEGKEYQFRVRAENAAGISEPSRATPPTKAVDPIDAPK 8310
Query: 1270 LTDLSFVDIT-------DSSIG------LRWTPLNSSTIIGYRITVVAA-------GEGI 1309
+ + +++ D+SI + W + + I+ I AA GE +
Sbjct: 8311 VILRTSLEVKRGDEIALDASISGSPYPTITWIK-DENVIVPEEIKKRAAPLVRRRKGE-V 8368
Query: 1310 PIFEDFVDSSVGYYTVTGLEPGI-----------DYDISVITLIN--GGESAPTTLTQQT 1356
E FV ++ + G D+ + +I + N G AP T++
Sbjct: 8369 QEEEPFVLPLTQRLSIDNSKKGESQLRVRDSLRPDHGLYMIKVENDHGIAKAPCTVSVLD 8428
Query: 1357 AVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVL 1416
PP + F +I ++ W PP D + ++ Y+ K ++ P +V+
Sbjct: 8429 TPGPPINFVFEDIRKTSVLCKWEPPLD-DGGSEIINYTLEKKDK------TKPDSEWIVV 8481
Query: 1417 TNLLPGTEYVVSVSSVYEQHE------------------STPLRGRQKTG-LDSPTGIDF 1457
T+ L +Y SV+ + E E S PL + G D+P
Sbjct: 8482 TSTLRHCKY--SVTKLIEGKEYLFRVRAENRFGPGPPCVSKPLVAKDPFGPPDAPDKPIV 8539
Query: 1458 SDITANSFTVHWIAPR---ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTE 1514
D+T+NS V W P+ + I GY + + + R ++ + + L G
Sbjct: 8540 EDVTSNSMLVKWNEPKDNGSPILGYWLEKREVNSTHWSRVNKSLLNALKANVDGLLEGLT 8599
Query: 1515 YVVSIVALN----GREESPLLIGQQSTVSD--------VPRDLEVVAATPTSLLISWDAP 1562
YV + A N G+ P T D +PR V + T++ + W+ P
Sbjct: 8600 YVFRVCAENAAGPGKFSPP---SDPKTAHDPISPPGPPIPR---VTDTSSTTIELEWEPP 8653
Query: 1563 AVT----VRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDS 1618
A + Y + G N + T+ ++ G DY + V AV G+
Sbjct: 8654 AFNGGGEIVGYFVDKQLVGTNEWSRCTEKMIKVRQYTVKEIREGADYKLRVSAVNAAGEG 8713
Query: 1619 -PASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTK 1677
P ++P+++ E +P +++ +SVK R+ P PTK
Sbjct: 8714 PPGETQPVTV---AEPQEPPAVEL------DVSVKGGIQIMAGKTLRIPAVVTGRPVPTK 8764
Query: 1678 --TKTAGP-DQTEMTIEGLQPTVEYVVS-----------VYAQNPSGESQPLVQTAVTNI 1723
TK G D+ + I+ + E ++ + A N G + V ++
Sbjct: 8765 VWTKEEGELDKDRVVIDNVGTKSELIIKDALRKDHGRYVITATNSCGSKFAAARVEVFDV 8824
Query: 1724 DRP-KGLAFTDVDVDSIKIAWESPQ----GQVSRYRVTYSSPEDGIHELFPAPDGEEDTA 1778
P L + + W P+ +++ + + + +H + E
Sbjct: 8825 PGPVLDLKPVVTNRKMCLLNWSDPEDDGGSEITGFIIERKDAK--MHTWRQPIETERSKC 8882
Query: 1779 ELQGLRPGSEYTVSVVALH-----DDMESQPLIGTQSTAIP-APTDLKFTQVTPTSLSAQ 1832
++ GL G EY V+A + +E P++ P +P L +T+ T ++++
Sbjct: 8883 DITGLLEGQEYKFRVIAKNKFGCGPPVEIGPILAVDPLGPPTSPERLTYTERTKSTITLD 8942
Query: 1833 WTPPNVQ----LTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKD 1888
W P + GY + +K + ++S +V L YE V A+ +
Sbjct: 8943 WKEPRSNGGSPIQGYIIEKRRHDKPDFERVNKRLCPTTSFLVENLDEHQMYEFRVKAVNE 9002
Query: 1889 TLTSRPA--QGVVTTLENVSPPRRARVTDATETTIT-------------------ISWRT 1927
S P+ VV + V P + R++ +T I W +
Sbjct: 9003 IGESEPSLPLNVVIQDDEVPPTIKLRLSVRGDTIKVKAGEPVHIPADVTGLPMPKIEW-S 9061
Query: 1928 KTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVV 1987
K ET+ DA+ + + K ++ GT YT+ + R V
Sbjct: 9062 KNETVIEKPTDALQITKEEVSRSEAKTELSIPKAVREDKGT------YTVTASNRLGSVF 9115
Query: 1988 IDASTAI-DAPSNLRFLATT---PNSLLVSWQPP----RARITGYII 2026
+ + D PS R LA T S ++W P + IT Y+I
Sbjct: 9116 RNVHVEVYDRPSPPRNLAVTDIKAESCYLTWDAPLDNGGSEITHYVI 9162
Score = 94.0 bits (232), Expect = 2e-18
Identities = 154/662 (23%), Positives = 253/662 (38%), Gaps = 93/662 (14%)
Query: 1538 VSDVP---RDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTA 1594
V DVP R+LEV + ++W+ P I Y + + + + ++ +
Sbjct: 6714 VIDVPGPVRNLEVTETFDGEVSLAWEEPLTDGGSKIIGYVVERRDIKRKTWVLATDRAES 6773
Query: 1595 ---TISGL-KPGVDYTITVYAVT--GRGDSPASSKPISINYRTEIDKPS-QMQVTDVQDN 1647
T++GL K GV+Y V A G G+ + P+ + ++ P + +TDV
Sbjct: 6774 CEFTVTGLQKGGVEYLFRVSARNRVGTGEPVETDNPVEARSKYDVPGPPLNVTITDVNRF 6833
Query: 1648 SISVKWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSV 1703
+S+ W P + +T Y + K T + T+ + EY V
Sbjct: 6834 GVSLTWEPPEYDGGAEITNYVIELRDKTSIRWDTAMTVRAEDLSATVTDVVEGQEYSFRV 6893
Query: 1704 YAQNPSGESQPLVQTAVTN----IDRPK---GLAFTDVDVDSIKIAWESPQGQVSRYRVT 1756
AQN G +P T I+RP L +D S+++ WE P +
Sbjct: 6894 RAQNRIGVGKPSAATPFVKVADPIERPSPPVNLTSSDQTQSSVQLKWEPPLKDGGSPILG 6953
Query: 1757 Y--SSPEDGIH-------ELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIG 1807
Y E+G +L P E T ++ GL G++Y V A + S P
Sbjct: 6954 YIIERCEEGKDNWIRCNMKLVP-----ELTYKVTGLEKGNKYLYRVSAENKAGVSDP--- 7005
Query: 1808 TQSTAIPAPTDLKFTQVTPT-SLSA-----QWTPPN-----VQLTGY-RVRVT-----PK 1850
+ I P V PT LSA + PN V TGY R T
Sbjct: 7006 ---SEILGPLTADDAFVEPTMDLSAFKDGLEVIVPNPITILVPSTGYPRPTATWCFGDKV 7062
Query: 1851 EKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGV--VTTLENVSPP 1908
+TG ++ + +V+S + + + +Y LK + G V + S P
Sbjct: 7063 LETGDRVKMKTLSAYAELVISP---SERSDKGIYTLKLENRVKTISGEIDVNVIARPSAP 7119
Query: 1909 RRARVTDATETTITISWRTKTET----ITGFQVDAVPANGQTPIQRTIKPDVRSYTITGL 1964
+ + D T+ ++ ++W + +TG+ V+ + +T + +T+ L
Sbjct: 7120 KELKFGDITKDSVHLTWEPPDDDGGSPLTGYVVEKREVSRKTWTKVMDFVTDLEFTVPDL 7179
Query: 1965 QPGTDYKIYLYTLNDNARSSPVVIDA-------STAIDAPSNLRFLATTPNSLLVSWQPP 2017
G +Y + N P +D +T D P N+++ T NS+ ++W PP
Sbjct: 7180 VQGKEYLFKVCARNKCGPGEPAYVDEPVNMSTPATVPDPPENVKWRDRTANSIFLTWDPP 7239
Query: 2018 R----ARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKS 2073
+ +RI GYI++ GS P T+ +TGLE G Y V AL S
Sbjct: 7240 KNDGGSRIKGYIVERCPRGSDKWVACGEP-VAETKMEVTGLEEGKWYAYRVKALNRQGAS 7298
Query: 2074 EPLIGRKKTDELPQLVTLPHPNLHGPEILDVPSTVQKTPFVTHPGYDTGNGIQLPGTSGQ 2133
+P + T+E+ + T P + LDV T G I+LP T
Sbjct: 7299 KP---SRPTEEIQAVDTQEAPEI----FLDVKLLAGLT-------VKAGTKIELPATVTG 7344
Query: 2134 QP 2135
+P
Sbjct: 7345 KP 7346
Score = 90.5 bits (223), Expect = 2e-17
Identities = 354/1666 (21%), Positives = 582/1666 (34%), Gaps = 229/1666 (13%)
Query: 624 NSHPIQWNAPQ---PSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKG--LKPGVVYE 678
+S + W P+ S I+ YI+ R S W+ + + TIK LK G Y+
Sbjct: 15884 DSITLSWGPPKYDGGSSINNYIVEKRD-TSTTTWQ--IVSATVARTTIKACRLKTGCEYQ 15940
Query: 679 GQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVV 738
++ + +YG + T V P +P+V S + S V
Sbjct: 15941 FRIAAENRYGKSTYLNSEPTVAQYPFKVPG-------PPGTPVVTLS------SRDSMEV 15987
Query: 739 SWVSASDTVSGFRVEYELS-EEGDEPQYLDL---PSTATSVNIPDLLPGRKYI--VNVYQ 792
W + Y L +E + ++ L P T L G +Y V+
Sbjct: 15988 QWNEPISDGGSRVIGYHLERKERNSILWVKLNKTPIPQTKFKTTGLEEGVEYEFRVSAEN 16047
Query: 793 ISEDGEQSLILSTSQTTAPDAPPD-PTVDQVDDTSIVVRWSRPQ----APITGYRIVYSP 847
I G+ S + P PP P V S+ ++W +P + ITGY +
Sbjct: 16048 IVGIGKPSKVSECYVARDPCDPPGRPEAIIVTRNSVTLQWKKPTYDGGSKITGYIVEKKE 16107
Query: 848 SVEG---SSTELNLPETANSVTLSDLQPGVQYNITIYA------VEENQESTPVVIQQET 898
EG ++ N+ +T VT L +Y + A E EST + ++
Sbjct: 16108 LPEGRWMKASFTNIIDTHFEVT--GLVEDHRYEFRVIARNAAGVFSEPSESTGAITARDE 16165
Query: 899 TGTPRSDTVPSPRDLQFVEVTD---VKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLP 955
PR P +D V + V I P + + I + + RL
Sbjct: 16166 VDPPRISMDPKYKDTIVVHAGESFKVDADIYGKPIPT------IQWIKGDQELSNTARLE 16219
Query: 956 ISRNTFAEVTGLSPGV-----TYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNE-T 1009
I FA + V Y K V+ G S + + + P ++ T
Sbjct: 16220 IKSTDFATSLSVKDAVRVDSGNYILKAKNVA-GERSVTVNVKVLDRPGPPEGPVVISGVT 16278
Query: 1010 DSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVS 1065
+ W PP + I Y + T R + + L +EYT
Sbjct: 16279 AEKCTLAWKPPLQDGGSDIINYIVERRETSRLVWTVVDANVQTLSCKVTKLLEGNEYTFR 16338
Query: 1066 LVAIKGNQ-----ESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWT-PAPR-----IG 1114
++A+ ES + P + P T VT+ ++++ W PA +G
Sbjct: 16339 IMAVNKYGVGEPLESEPVVAKNPFVVPDAPKAPEVTTVTKDSMIVVWERPASDGGSEILG 16398
Query: 1115 FKLGVRPSQGGEAPREVTSDSGSIV--VSGLTPGVEYVYTIQVLRD-GQERDAP--IVNK 1169
+ L R +G R G + V+GL +Y + + G +P K
Sbjct: 16399 YVLEKRDKEGIRWTRCHKRLIGELRLRVTGLIENHDYEFRVSAENAAGLSEPSPPSAYQK 16458
Query: 1170 VVTPL---SPPTNLHLEANPDTGVLTVSWERSTTP---DITGYRITTTPTNGQQGNSLEE 1223
P+ PP N + + V +SW + +I GY + + +
Sbjct: 16459 ACDPIYKPGPPNNPKVIDITRSSVF-LSWSKPIYDGGCEIQGYIVEKCDVSVGEWTMCTP 16517
Query: 1224 VVHADQSSCTFDNLSPGLEYNVSVYTVKD----DKESVPISDTIIPEVPQLTDLSFVDIT 1279
++++ + L EYN + + + VP I+ E + D+
Sbjct: 16518 PTGINKTNIEVEKLLEKHEYNFRICAINKAGVGEHADVP-GPIIVEEKLEAPDI------ 16570
Query: 1280 DSSIGLRWTPLNSSTIIGYRITVVAAGEGIP----------IFEDFVDSSVGYYTVTGLE 1329
D + LR +N R+ V G P I + + +T L+
Sbjct: 16571 DLDLELRKI-INIRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTSSFTSLVLD 16629
Query: 1330 PGIDYDISVITLI----NGGESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAPPPSID 1385
YD TL +G +SA T+ PP +L+ T I D++ +TW PP +D
Sbjct: 16630 NVNRYDSGKYTLTLENSSGTKSAFVTVRVLDTPSPPVNLKVTEITKDSVSITW-EPPLLD 16688
Query: 1386 LTNFLVRYSPVKNE---EDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLR 1442
+ + Y K E + A + + N+ + L G Y V++ E P +
Sbjct: 16689 GGSKIKNYIVEKREATRKSYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAENEYGIGLPAQ 16748
Query: 1443 GRQKTGL----DSPTGIDFSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPRE 1494
+ P I D+T NS ++ W P + I Y + +H
Sbjct: 16749 TADPIKVAEVPQPPGKITVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKHSEKWSEC 16808
Query: 1495 DRVPHSRNSITLTNLTPGTEYVVSIVALNGREES-PLLIGQQSTVSDVPRDLEVVAA-TP 1552
RV + +TNLT G EY+ +VA+N + S P + D+ + +V A +
Sbjct: 16809 ARVKSLQ--AVITNLTQGEEYLFRVVAVNEKGRSDPRSLAVPIVAKDLVIEPDVKPAFSS 16866
Query: 1553 TSLLISWD----APAVTVRYYRITYGETGGNSPVQEFT---VPGSKSTATIS----GLKP 1601
S+ + D P IT+ + G P+++ T V S T+S
Sbjct: 16867 YSVQVGQDLKIEVPISGRPKPTITWTKDG--LPLKQTTRINVTDSLDLTTLSIKETHKDD 16924
Query: 1602 GVDYTITVYAVTGRGDSPASSKPISINYRTEIDKP----SQMQVTDVQDNSISVKWLP-- 1655
G Y ITV V G+ K SI T +DKP ++ DV SI++ W P
Sbjct: 16925 GGQYGITVANVVGQ-------KTASIEIVT-LDKPDPPKGPVKFDDVSAESITLSWNPPL 16976
Query: 1656 --SSSPVTGYRV-----TTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNP 1708
+T Y V TTT + T +T + + L+ EY ++A+N
Sbjct: 16977 YTGGCQITNYIVQKRDTTTTVWDVVSATVARTT------LKVTKLKTGTEYQFRIFAENR 17030
Query: 1709 SG-----ESQPLVQTAVTNIDRPKGLAF-TDVDVDSIKIAWESPQGQVSRYRVTYSSPED 1762
G ES P+V P G F T + DS+ I W P + Y
Sbjct: 17031 YGQSFALESDPIVAQYPYKEPGPPGTPFATAISKDSMVIQWHEPVNNGGSPVIGYHLERK 17090
Query: 1763 GIHELFPAPDGE---EDTA-ELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTD 1818
+ + + DT + Q L G EY V A + + ++ P D
Sbjct: 17091 ERNSILWTKVNKTIIHDTQFKAQNLEEGIEYEFRVYAENIVGVGKASKNSECYVARDPCD 17150
Query: 1819 LKFT----QVTPTSLSAQWTPP----NVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVV 1870
T V ++ QWT P +TGY V MK + V
Sbjct: 17151 PPGTPEPIMVKRNEITLQWTKPVYDGGSMITGYIVEKRDLPDGRWMKASFTNVIETQFTV 17210
Query: 1871 SGLMVATKYEVSVYALKDT-LTSRPAQ--GVVTTLENVSPPRRARVTDATETTITISWRT 1927
SGL +YE V A S+P+ G +T + V PR + +T + + T
Sbjct: 17211 SGLTEDQRYEFRVIAKNAAGAISKPSDSTGPITAKDEVELPRISMDPKFRDTIVVNAGET 17270
Query: 1928 KTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQ-PGTDYKIYL------------ 1974
F+++A P ++ D + TD+K L
Sbjct: 17271 -------FRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRIDGGQ 17323
Query: 1975 YTLNDN----ARSSPV---VIDASTAIDAPSNLRFLATTPNSLLVSWQPP----RARITG 2023
Y L + ++S PV V+D + P ++ T ++W PP + I+
Sbjct: 17324 YILRASNVAGSKSFPVNVKVLDRPGPPEGP--VQVTGVTSEKCSLTWSPPLQDGGSDISH 17381
Query: 2024 YIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTD 2083
Y+++ ++ S V +T L G EY ++A+ EPL +
Sbjct: 17382 YVVE-KRETSRLAWTVVASEVVTNSLKVTKLLEGNEYVFRIMAVNKYGVGEPL------E 17434
Query: 2084 ELPQLVTLPHPNLHGPEILDVPSTVQKTPFVTHPGYDTGNGIQLPG 2129
P L+ P P+ L+V + + + V D+ G ++ G
Sbjct: 17435 SAPVLMKNPFVLPGPPKSLEVTNIAKDSMTVCWNRPDSDGGSEIIG 17480
Score = 86.7 bits (213), Expect = 3e-16
Identities = 349/1678 (20%), Positives = 599/1678 (35%), Gaps = 279/1678 (16%)
Query: 628 IQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISI 684
+ W+ P+ S I+ +I+ R + W++ I + I GL G Y+ ++I+
Sbjct: 8843 LNWSDPEDDGGSEITGFIIE-RKDAKMHTWRQP-IETERSKCDITGLLEGQEYKFRVIAK 8900
Query: 685 QQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWV--- 741
++G PV + P + TE T S+ + W
Sbjct: 8901 NKFG-------------CGPPVEIGPILAVDPLGPPTSPERLTYTERTKSTITLDWKEPR 8947
Query: 742 -SASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQS 800
+ + G+ +E ++ D + TS + +L + Y V ++E GE
Sbjct: 8948 SNGGSPIQGYIIEKRRHDKPDFERVNKRLCPTTSFLVENLDEHQMYEFRVKAVNEIGESE 9007
Query: 801 LILSTSQTTAPDAPPDPTVD---QVDDTSIVVRWSRP---QAPITGYRIVYSPSVEGSST 854
L + D P PT+ V +I V+ P A +TG + P +E S
Sbjct: 9008 PSLPLNVVIQDDEVP-PTIKLRLSVRGDTIKVKAGEPVHIPADVTGLPM---PKIEWSKN 9063
Query: 855 E--LNLPETANSVTLSDLQPG-VQYNITI-YAVEENQESTPVVIQQETTGTPRS------ 904
E + P A +T ++ + ++I AV E++ + V R+
Sbjct: 9064 ETVIEKPTDALQITKEEVSRSEAKTELSIPKAVREDKGTYTVTASNRLGSVFRNVHVEVY 9123
Query: 905 DTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPGEHGQRLPISRNT 960
D PR+L ++ + W P S +T Y +D + + + NT
Sbjct: 9124 DRPSPPRNLAVTDIKAESCYLTWDAPLDNGGSEITHYVIDKRDASRKKAEWEEVT---NT 9180
Query: 961 FAE----VTGLSPGVTYYFKV-----FAVSHGRESKPLTAQQTTKLDAPTNL-QFVNETD 1010
E + L P Y F+V + +S +S + Q +L P + + T
Sbjct: 9181 AVEKRYGIWKLIPNGQYEFRVRAVNKYGISDECKSDKVVIQDPYRLPGPPGKPKVLARTK 9240
Query: 1011 STVLVRWTPPR----AQITGYRLTVGLTRRGQPRQY----------NVGPSVSKYPLRNL 1056
++LV WTPP + ITGY L +R + Y VG ++ + L
Sbjct: 9241 GSMLVSWTPPLDNGGSPITGY----WLEKREEGSPYWSRVSRAPITKVGLKGVEFNVPRL 9296
Query: 1057 QPASEYTVSLVAIKG-------NQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTP 1109
+Y +AI P+ G PG P + T+++I + W P
Sbjct: 9297 LEGVKYQFRAMAINAAGIGPPSEPSDPEVAGD-PIFPPGPPSCPEVKDKTKSSISLGWKP 9355
Query: 1110 APRIGFKLGVRPSQGG--EAPREVTSDSGSI------------VVSGLTPGVEYVYTIQV 1155
K G P +G E E T+D + VV L +Y + ++
Sbjct: 9356 PA----KDGGSPIKGYIVEMQEEGTTDWKRVNEPDKLITTCECVVPNLKELRKYRFRVKA 9411
Query: 1156 LRD-GQERDAPIVNKV-VTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPT 1213
+ + G+ + ++ T + + ++ ++ + + P + R T +
Sbjct: 9412 VNEAGESEPSDTTGEIPATDIQEEPEVFIDIGAQDCLVCKAGSQIRIPAVIKGRPTPKSS 9471
Query: 1214 ---NGQQGNSLEEVVH---ADQSSCTFDNLSPGL----------EYNVSVYTVKDDKES- 1256
+G+ ++++ VH D T +N S + +Y+++ K +
Sbjct: 9472 WEFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECKRSHTGKYSITAKNKAGQKTAN 9531
Query: 1257 --VPISDTIIPEVPQLTDLSFVDITDSSIGLRWTPLNSS---TIIGYRITVVAAGEGIPI 1311
V + D +P P+ DL DIT S L W + I GY I +G
Sbjct: 9532 CRVKVMD--VPGPPK--DLKVSDITRGSCRLSWKMPDDDGGDRIKGYVIEKRTI-DGKAW 9586
Query: 1312 FEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAV-------PPPTDL 1364
+ D + V L Y V G P Q+T PP L
Sbjct: 9587 TKVNPDCGSTTFVVPDLLSEQQYFFRVRAENRFGIGPPVETIQRTTARDPIYPPDPPIKL 9646
Query: 1365 RFTNIGPDTMRVTWAPPPS---IDLTNFLVR---YSPVK---------NEEDVAELSISP 1409
+ I +T+ ++W PP + +T+++V + P N+ DV EL +
Sbjct: 9647 KIGLITKNTVHLSWKPPKNDGGSPVTHYIVECLAWDPTGTKKEAWRQCNKRDVEELQFTV 9706
Query: 1410 SDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGL---DSPTGIDFSDI--TANS 1464
D L+ G EY V +V S P D P ID +
Sbjct: 9707 ED-------LVEGGEYEFRVKAVNAAGVSKPSATVGPCDCQRPDMPPSIDLKEFMEVEEG 9759
Query: 1465 FTVHWIA-----PRATITGYRIRH----------HPEHFSGRPREDR----VPHSRNSIT 1505
V+ +A P T+T ++ + H + +D +P SR S T
Sbjct: 9760 TNVNIVAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDT 9819
Query: 1506 LTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAP--- 1562
Y ++ V G + + ++ + + + +SW P
Sbjct: 9820 GL-------YTITAVNNLGTASKEMRLNVLGRPGPPVGPIKFESVSADQMTLSWFPPKDD 9872
Query: 1563 -AVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRG-DSPA 1620
+ Y I E + V + P + T TI L G +Y + A G P
Sbjct: 9873 GGSKITNYVIEKREANRKTWVHVSSEP-KECTYTIPKLLEGHEYVFRIMAQNKYGIGEPL 9931
Query: 1621 SSKPISI-NYRTEIDKPSQMQVTDVQDNSISVKW----LPSSSPVTGYRVT---TTPKN- 1671
S+P + N + P + V+ V NS++V W SPVTGY + TT K
Sbjct: 9932 DSEPETARNLFSVPGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPVTGYWLEMKDTTSKRW 9991
Query: 1672 ---GPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSG---ESQPLVQTAVTNIDR 1725
P K T G + GL +Y VYA N +G S P +
Sbjct: 9992 KRVNRDPIKAMTLG---VSYKVTGLIEGSDYQFRVYAINAAGVGPASLPSDPATARDPIA 10048
Query: 1726 PKGLAF---TDVDVDSIKIAWESPQ----GQVSRYRVTYSSPEDGIHELFPAPDGEEDTA 1778
P G F TD S + W P +V+ Y V Y E+G E D E
Sbjct: 10049 PPGPPFPKVTDWTKSSADLEWSPPLKDGGSKVTGYIVEYK--EEGKEEWEKGKDKEVRGT 10106
Query: 1779 EL--QGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPT-SLSAQWTP 1835
+L GL+ G+ Y V A++ +P G + I ++K V+P L A
Sbjct: 10107 KLVVTGLKEGAFYKFRVRAVNIAGIGEP--GEVTDVI----EMKDRLVSPDLQLDASVRD 10160
Query: 1836 PNVQLTGYRVRVT-------PKEKTGPMKEINLAPDSS--SVVVSGLMVATKYEVS---V 1883
V G +R+ P T M E L +++ + +S MV + S V
Sbjct: 10161 RIVVHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEATIETTAISSSMVIKNCQRSHQGV 10220
Query: 1884 YAL--KDTLTSRPAQGVVTTLENVSPPRRARVT-DATETTITISWRTKTET----ITGFQ 1936
Y+L K+ R +V L+ P + + T + ++W + + IT +
Sbjct: 10221 YSLLAKNEAGERKKTIIVDVLDVPGPVGTPFLAHNLTNESCKLTWFSPEDDGGSPITNYV 10280
Query: 1937 VDAVPANGQ--TPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLND-------NARSSPVV 1987
++ ++ + TP+ T+ ++ T+ GL G Y + N + V+
Sbjct: 10281 IEKRESDRRAWTPVTYTVTR--QNATVQGLIQGKAYFFRIAAENSIGMGPFVETSEALVI 10338
Query: 1988 IDASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREVVPRPR 2043
+ T + P +L T N++ ++W PP+ + I Y+++ G+ V
Sbjct: 10339 REPITVPERPEDLEVKEVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEKFHKVTNDN 10398
Query: 2044 PGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELPQLVT----LPHPNLH 2097
+ T+ GL+ G Y V A+ ++G+ K + +T L P LH
Sbjct: 10399 LLSRKYTVKGLKEGDTYEYRVSAVN-------IVGQGKPSFCTKPITCKDELAPPTLH 10449
Score = 86.7 bits (213), Expect = 3e-16
Identities = 320/1612 (19%), Positives = 550/1612 (34%), Gaps = 233/1612 (14%)
Query: 630 WNAPQPSH---ISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQ 686
W+ P+ IS Y++ R +S W E +Y L G+ Y+ ++ + +
Sbjct: 14808 WDPPENDGGVPISNYVVEMRQTDST-TWVELATTVIRTTYKATRLTTGLEYQFRVKAQNR 14866
Query: 687 YGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSW----VS 742
YG +TS + P + VT +T S +SW
Sbjct: 14867 YG-------------VGPGITSACIVANYPFKVPGPPGTPQVTAVTKDSMTISWHEPLSD 14913
Query: 743 ASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNI---PDLLPGRKYIVNVYQISEDGEQ 799
+ G+ VE +E + + + NI L G Y V + G+
Sbjct: 14914 GGSPILGYHVE---RKERNGILWQTVSKALVPGNIFKSSGLTDGIAYEFRVIAENMAGKS 14970
Query: 800 SLILSTSQTTAPDA---PPDPTVDQVDDTSIVVRWSRPQAP----ITGYRIVYSPSVEGS 852
+ A D P P + ++ ++W++P+ IT Y + G
Sbjct: 14971 KPSKPSEPMLALDPIDPPGKPVPLNITRHTVTLKWAKPEYTGGFKITSYIVEKRDLPNGR 15030
Query: 853 STELNLPETA-NSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPR 911
+ N N T+S L Y + A +P + + D V +P+
Sbjct: 15031 WLKANFSNILENEFTVSGLTEDAAYEFRVIAKNAAGAISPP--SEPSDAITCRDDVEAPK 15088
Query: 912 ---DLQFVEVTDVKV----------------TIMWTPPESAVTG-----YRVDVIPVNLP 947
D++F + +K T+ W+ + G ++ NL
Sbjct: 15089 IKVDVKFKDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLV 15148
Query: 948 GEHGQRLPISRNTFAEVTGLSPG--VTYYFKVFAVSH-GRESKPLTAQQTTKLDAPTNLQ 1004
+ R T +T +PG + F V + G PL + T
Sbjct: 15149 NKDSTRRDSGAYT---LTATNPGGFAKHIFNVKVLDRPGPPEGPLAVTEVTS-------- 15197
Query: 1005 FVNETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPAS 1060
++ W PP A+I Y + T R V+K + L +
Sbjct: 15198 ------EKCVLSWFPPLDDGGAKIDHYIVQKRETSRLAWTNVASEVQVTKLKVTKLLKGN 15251
Query: 1061 EYTVSLVAIK--GNQESPKATGVFTTLQPGSSIPPYNTEVTETT---IVITWTPAPRIGF 1115
EY ++A+ G E ++ V G PP N EVT T +V+ W G
Sbjct: 15252 EYIFRVMAVNKYGVGEPLESEPVLAVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGG 15311
Query: 1116 K-----LGVRPSQGGEAPREVTSDSGSIV-----VSGLTPGVEYVYTIQVLR----DGQE 1161
+ R + G+ R + + ++ VSGLT G EY + I
Sbjct: 15312 SEIINYIVERRDKAGQ--RWIKCNKKTLTDLRYKVSGLTEGHEYEFRIMAENAAGISAPS 15369
Query: 1162 RDAPIVNKVVTPLSP-PTNLHLEANPDTGVLTVSWERSTTP---DITGYRITTTPTNGQQ 1217
+P T P P + ++++W + +ITGY + +
Sbjct: 15370 PTSPFYKACDTVFKPGPPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIALPEEDE 15429
Query: 1218 GNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPEVPQLTDLSFVD 1277
+ +S T L+ EY + +Y + + P ++P P+ D
Sbjct: 15430 WQIVTPPAGLKATSYTITGLTENQEYKIRIYAMNSEGLGEP---ALVPGTPKAEDRMLPP 15486
Query: 1278 ITDSSIGLRWTPLNSSTIIGYRITVVAAGEGIP-----------IFEDFVDSSVGY-YTV 1325
+ LR + R+ V G P + + ++S+ Y +
Sbjct: 15487 EIELDADLRKV-VTIRACCTLRLFVPIKGRPAPEVKWARDHGESLDKASIESTSSYTLLI 15545
Query: 1326 TGLEPGIDYDISVITLIN--GGESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAPPPS 1383
G D ++T+ N G +SA + PP DL+ + ++ +TW PP
Sbjct: 15546 VGNVNRFDSGKYILTVENSSGSKSAFVNVRVLDTPGPPQDLKVKEVTKTSVTLTW-DPPL 15604
Query: 1384 IDLTNFLVRYSPVKNEEDVAELSISPSD---NAVVLTNLLPGTEYVVSVSSVYEQHESTP 1440
+D + + Y K E S ++ + + L G Y V + E P
Sbjct: 15605 LDGGSKIKNYIVEKRESTRKAYSTVATNCHKTSWKVDQLQEGCSYYFRVLAENEYGIGLP 15664
Query: 1441 LRGRQKTGLDS----PTGIDFSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRP 1492
+ P I D+T NS ++ W P + I GY + +
Sbjct: 15665 AETAESVKASERPLPPGKITLMDVTRNSVSLSWEKPEHDGGSRILGYIVEMQTKGSDKWA 15724
Query: 1493 REDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAA-- 1550
V + T+T L G EY + A N E + +Q +V + +DL + A
Sbjct: 15725 TCATVKVTE--ATITGLIQGEEYSFRVSAQN---EKGISDPRQLSVPVIAKDLVIPPAFK 15779
Query: 1551 ----TPTSLL---ISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGL--KP 1601
T T L + D P + +T+ + N P+++ T ++ST S L K
Sbjct: 15780 LLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKD--NVPLKQTTRVNAESTENNSLLTIKD 15837
Query: 1602 GVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQ----MQVTDVQDNSISVKWLP-- 1655
+ Y V + + + +++ +DKP +++ +V +SI++ W P
Sbjct: 15838 ACREDVGHYVVKLTNSAGEAIETLNV---IVLDKPGPPTGPVKMDEVTADSITLSWGPPK 15894
Query: 1656 --SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEG--LQPTVEYVVSVYAQNPSGE 1711
S + Y V K T + TI+ L+ EY + A+N G+
Sbjct: 15895 YDGGSSINNYIVE---KRDTSTTTWQIVSATVARTTIKACRLKTGCEYQFRIAAENRYGK 15951
Query: 1712 S-----QPLVQTAVTNIDRPKGLAFTDVDV-DSIKIAWESPQGQVSRYRVTYSSPEDGIH 1765
S +P V + P G + DS+++ W P + Y +
Sbjct: 15952 STYLNSEPTVAQYPFKVPGPPGTPVVTLSSRDSMEVQWNEPISDGGSRVIGYHLERKERN 16011
Query: 1766 ELF-------PAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTD 1818
+ P P + T GL G EY V A + +P ++ P D
Sbjct: 16012 SILWVKLNKTPIPQTKFKTT---GLEEGVEYEFRVSAENIVGIGKPSKVSECYVARDPCD 16068
Query: 1819 L----KFTQVTPTSLSAQWTPPNV----QLTGYRVRVTPKEKTGPMKEINLAPDSSSVVV 1870
+ VT S++ QW P ++TGY V + MK + V
Sbjct: 16069 PPGRPEAIIVTRNSVTLQWKKPTYDGGSKITGYIVEKKELPEGRWMKASFTNIIDTHFEV 16128
Query: 1871 SGLMVATKYEVSVYALKDT-LTSRPAQ--GVVTTLENVSPPRRARVTDATETTITISWRT 1927
+GL+ +YE V A + S P++ G +T + V PPR + +T + + +
Sbjct: 16129 TGLVEDHRYEFRVIARNAAGVFSEPSESTGAITARDEVDPPRISMDPKYKDTIVVHAGES 16188
Query: 1928 KTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQ-PGTDYKIYLYTLNDNAR--SS 1984
F+VDA P + IK D L+ TD+ L ++ D R S
Sbjct: 16189 -------FKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSL-SVKDAVRVDSG 16240
Query: 1985 PVVIDASTAIDAPS---NLRFL-------------ATTPNSLLVSWQPPR----ARITGY 2024
++ A S N++ L T ++W+PP + I Y
Sbjct: 16241 NYILKAKNVAGERSVTVNVKVLDRPGPPEGPVVISGVTAEKCTLAWKPPLQDGGSDIINY 16300
Query: 2025 IIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPL 2076
I++ + VV +T L G EYT ++A+ EPL
Sbjct: 16301 IVERRETSRLVWTVVDA-NVQTLSCKVTKLLEGNEYTFRIMAVNKYGVGEPL 16351
Score = 86.3 bits (212), Expect = 3e-16
Identities = 362/1829 (19%), Positives = 635/1829 (34%), Gaps = 273/1829 (14%)
Query: 628 IQWNAPQPS---HISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISI 684
+ WN P + I+ YI++ R + W + + + LK G Y+ ++ +
Sbjct: 16970 LSWNPPLYTGGCQITNYIVQKRDTTTTV-WDVVSATVARTTLKVTKLKTGTEYQFRIFAE 17028
Query: 685 QQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSAS 744
+YG D P+ + E P AT+ I+ S V+ W
Sbjct: 17029 NRYGQSFALESD--------PIVAQYPYKEPGPPGTPFATA-----ISKDSMVIQWHEPV 17075
Query: 745 DTVSGFRVEYELS-EEGDEPQYLDLPSTA---TSVNIPDLLPG-----RKYIVNVYQISE 795
+ + Y L +E + + + T T +L G R Y N+ + +
Sbjct: 17076 NNGGSPVIGYHLERKERNSILWTKVNKTIIHDTQFKAQNLEEGIEYEFRVYAENIVGVGK 17135
Query: 796 DGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ----APITGYRIVYSPSVEG 851
+ S P P+P + V I ++W++P + ITGY + +G
Sbjct: 17136 ASKNSECYVARDPCDPPGTPEPIM--VKRNEITLQWTKPVYDGGSMITGYIVEKRDLPDG 17193
Query: 852 ---SSTELNLPETANSVTLSDLQPGVQYNITIYA------VEENQESTPVVIQQETTGTP 902
++ N+ ET T+S L +Y + A + + +ST + ++ P
Sbjct: 17194 RWMKASFTNVIET--QFTVSGLTEDQRYEFRVIAKNAAGAISKPSDSTGPITAKDEVELP 17251
Query: 903 RSDTVPSPRDLQFVEVTDV-----------KVTIMWTPPESAVTGYRVDVIPVNLPGEHG 951
R P RD V + TI W + + E
Sbjct: 17252 RISMDPKFRDTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEI--------------EES 17297
Query: 952 QRLPISRNTFAEVTGLSPGVT-----YYFKVFAVSHGRESKPLTAQQTTKLDAPTN-LQF 1005
R I F + + + Y + V+ G +S P+ + + P +Q
Sbjct: 17298 ARCEIKNTDFKALLIVKDAIRIDGGQYILRASNVA-GSKSFPVNVKVLDRPGPPEGPVQV 17356
Query: 1006 VNETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASE 1061
T + W+PP + I+ Y + T R + + L +E
Sbjct: 17357 TGVTSEKCSLTWSPPLQDGGSDISHYVVEKRETSRLAWTVVASEVVTNSLKVTKLLEGNE 17416
Query: 1062 YTVSLVAIK--GNQESPKATGVFTT---LQPGSSIPPYNTEVT---ETTIVITWTPAPR- 1112
Y ++A+ G E ++ V + PG PP + EVT + ++ + W
Sbjct: 17417 YVFRIMAVNKYGVGEPLESAPVLMKNPFVLPG---PPKSLEVTNIAKDSMTVCWNRPDSD 17473
Query: 1113 -----IGFKLGVRPSQGGE----APREVTSDSGSIVVSGLTPGVEYVYTIQVLRD---GQ 1160
IG+ + R G R +T + V+GLT EY + + G+
Sbjct: 17474 GGSEIIGYIVEKRDRSGIRWIKCNKRRITDLR--LRVTGLTEDHEYEFRVSAENAAGVGE 17531
Query: 1161 ERDAPIVNKVVTPL---SPPTNLHLEANPDTGVLTVSWERSTTP---DITGYRITTTPTN 1214
A + K P+ PPTN H+ + +T++W + +I GY + +
Sbjct: 17532 PSPATVYYKACDPVFKPGPPTNAHI-VDTTKNSITLAWGKPIYDGGSEILGYVVEICKAD 17590
Query: 1215 GQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDK--ESVPISDTIIPE----VP 1268
++ + + L+ EY + V + E+ + T+ PE P
Sbjct: 17591 EEEWQIVTPQTGLRVTRFEISKLTEHQEYKIRVCALNKVGLGEATSVPGTVKPEDKLEAP 17650
Query: 1269 QLTDLSFVDITDSSIGLRWTPLNSSTII--GYRITVVAAGEGIPIFEDFVDSSVGYYT-V 1325
+L DL + L ++ G + +G P E G +T
Sbjct: 17651 EL-DLD-------------SELRKGIVVRAGGSARIHIPFKGRPTPEITWSREEGEFTDK 17696
Query: 1326 TGLEPGIDYD---------------ISVITLINGGESAPTTLTQQTAVPPPTDLRFTNIG 1370
+E G++Y I + +G +SA T+ PP +L +
Sbjct: 17697 VQIEKGVNYTQLSIDNCDRNDAGKYILKLENSSGSKSAFVTVKVLDTPGPPQNLAVKEVR 17756
Query: 1371 PDTMRVTWAPPPSIDLTNFLVRYSPVKNEED---VAELSISPSDNAVVLTNLLPGTEYVV 1427
D+ + W PP ID + Y K E A +S S + + NL G Y
Sbjct: 17757 KDSAFLVWEPP-IIDGGAKVKNYVIDKRESTRKAYANVSSKCSKTSFKVENLTEGAIYYF 17815
Query: 1428 SVSSVYEQHESTPLR---GRQKTGLDSPTG-IDFSDITANSFTVHWIAPR----ATITGY 1479
V + E P+ + SP G + +D++ S ++ W P + + GY
Sbjct: 17816 RVMAENEFGVGVPVETVDAVKAAEPPSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLGY 17875
Query: 1480 RIRHHPEHFSGRPREDRVPHSRN-SITLTNLTPGTEYVVSIVALNGREES-PLLIGQQST 1537
+ P+ G + V S+ + +T L+ G EY + A N + +S P ++G
Sbjct: 17876 VVEMQPK---GTEKWSIVAESKVCNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVI 17932
Query: 1538 VSDVPRDLEVVAATPTSLL-----ISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKS 1592
D+ + T + + + P + I++ + G P+++ T +
Sbjct: 17933 AKDLTIQPSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDG--EPLKQTTRVNVEE 17990
Query: 1593 TAT--ISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKP-SQMQVTDVQDNSI 1649
TAT + +K G Y VT + +++ +S+ + P ++ +V + +
Sbjct: 17991 TATSTVLHIKEGNKDDFGKYTVTATNSAGTATENLSVIVLEKPGPPVGPVRFDEVSADFV 18050
Query: 1650 SVKWLPSS----SPVTGYRV-----TTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYV 1700
+ W P + ++ Y V TTT + T +T + I L+ EY
Sbjct: 18051 VISWEPPAYTGGCQISNYIVEKRDTTTTTWHMVSATVARTT------IKITKLKTGTEYQ 18104
Query: 1701 VSVYAQNPSGESQPLVQTAVT-----NIDRPKGLAF-TDVDVDSIKIAWESPQGQVSRYR 1754
++A+N G+S PL AV P G F T + D + + W P
Sbjct: 18105 FRIFAENRYGKSAPLDSKAVIVQYPFKEPGPPGTPFVTSISKDQMLVQWHEPVNDGGTKI 18164
Query: 1755 VTYSSPEDGIHELF-------PAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIG 1807
+ Y + + + P D + T GL G EY V A + +P
Sbjct: 18165 IGYHLEQKEKNSILWVKLNKTPIQDTKFKTT---GLDEGLEYEFKVSAENIVGIGKPSKV 18221
Query: 1808 TQSTAIPAPTD----LKFTQVTPTSLSAQWTPP----NVQLTGYRVRVTPKEKTGPMKEI 1859
++ P D + +T +++ +W P ++TGY V MK
Sbjct: 18222 SECFVARDPCDPPGRPEAIVITRNNVTLKWKKPAYDGGSKITGYIVEKKDLPDGRWMKAS 18281
Query: 1860 NLAPDSSSVVVSGLMVATKYEVSVYALKDTLT-SRP--AQGVVTTLENVSPPRRAR---- 1912
+ VSGL+ +YE V A S P + G +T + + P +
Sbjct: 18282 FTNVLETEFTVSGLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARDEIDAPNASLDPKY 18341
Query: 1913 ----VTDATET-TITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQ-P 1966
V A ET + R K + D +T + IK ++ T+
Sbjct: 18342 KDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELE-ETAARMEIKSTIQKTTLVVKDCI 18400
Query: 1967 GTDYKIYLYTLND--NARSSPVVIDASTAIDAPSN-LRFLATTPNSLLVSWQPP----RA 2019
TD Y+ L++ +S P+ + P L+ T ++W PP A
Sbjct: 18401 RTDGGQYILKLSNVGGTKSIPITVKVLDRPGPPEGPLKVTGVTAEKCYLAWNPPLQDGGA 18460
Query: 2020 RITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGR 2079
I+ YII+ + V + +T L PG EY V+A+ EPL
Sbjct: 18461 NISHYIIEKRETSRLSWTQVSTEVQAL-NYKVTKLLPGNEYIFRVMAVNKYGIGEPL--- 18516
Query: 2080 KKTDELPQLVTLPHPNLHGPEILDVPSTVQKTPFVTHPGYDTGNGIQLPGTSGQQPSVGQ 2139
+ P P+ P +V + + + VT G ++ G ++
Sbjct: 18517 ---ESGPVTACNPYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILEKR---- 18569
Query: 2140 QMIFEEHGFRRT-TPPTTATPIRHR------PRPYPPNVGEE--IQIGHIPREDVDYH-- 2188
++ G R T T T +R R Y V E +G V Y
Sbjct: 18570 ----DKEGVRWTKCNKKTLTDLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRAC 18625
Query: 2189 --LYPHGPGLNPNASTGQEALSQTTISWA-PFQD----TSEYIISCHPVGTDEEPLQFRV 2241
LYP GP NP + + S +++W+ P D Y++ DE
Sbjct: 18626 DALYPPGPPSNPKVT--DTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAADEWTTCTPP 18683
Query: 2242 PG-TSTSATLTGLTRGATYNIIVEALKDQ 2269
G T+T L YN + A+ +
Sbjct: 18684 TGLQGKQFTVTKLKENTEYNFRICAINSE 18712
Score = 84.3 bits (207), Expect = 1e-15
Identities = 263/1195 (22%), Positives = 417/1195 (34%), Gaps = 139/1195 (11%)
Query: 624 NSHPIQWNAPQ---PSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQ 680
N+ + WN P+ S I Y+L R + K YT+KGLK G YE +
Sbjct: 10359 NTVTLTWNPPKYDGGSEIINYVLESRLIGTEKFHKVTNDNLLSRKYTVKGLKEGDTYEYR 10418
Query: 681 LISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSW 740
+ ++ G + + + P+T E P + + + +T +F ++
Sbjct: 10419 VSAVNIVGQGK-------PSFCTKPITCK---DELAPPTLHLDFRDKLTIRVGEAFALTG 10468
Query: 741 ---VSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNI-PDLLPGRKYIVNVYQISED 796
VS F+ E ++ E+ D P+T I KY V V +
Sbjct: 10469 RYSGKPKPKVSWFKDEADVLED-DRTHIKTTPATLALEKIKAKRSDSGKYCVVVE--NST 10525
Query: 797 GEQSLILSTSQTTAPDAPPDP-TVDQVDDTSIVVRWSRP----QAPITGYRIVYSPSVEG 851
G + + P P P + D+V +V+ W P + IT Y I +
Sbjct: 10526 GSRKGFCQVNVVDRPGPPVGPVSFDEVTKDYMVISWKPPLDDGGSKITNYIIEKKEVGKD 10585
Query: 852 SSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPR 911
+ + +S L G Y I+A S P+V ++ VP
Sbjct: 10586 VWMPVTSASAKTTCKVSKLLEGKDYIFRIHAENLYGISDPLV--SDSMKAKDRFRVPDAP 10643
Query: 912 DLQFV-EVTDVKVTIMWTPPESA---VTGYRVDV-IPVNLPGEHGQRLPISRNTFAEVTG 966
D V EVT + W P +T Y ++ ++ + PI T V
Sbjct: 10644 DQPIVTEVTKDSALVTWNKPHDGGKPITNYILEKRETMSKRWARVTKDPIHPYTKFRVPD 10703
Query: 967 LSPGVTYYFKVFAVSH------GRESKPLTAQQ-TTKLDAPTNLQFVNETDSTVLVRWTP 1019
L G Y F+V A + SKP+ A+ K P N + ++ T ++V + W P
Sbjct: 10704 LLEGCQYEFRVSAENEIGIGDPSPPSKPVFAKDPIAKPSPPVNPEAIDTTCNSVDLTWQP 10763
Query: 1020 PR----AQITGYRLTVGLTRRGQPRQYNVGPS---VSKYPLRNLQPASEYTVSLVAIKGN 1072
PR ++I GY + + R+ N P +KY + L+ Y ++A+
Sbjct: 10764 PRHDGGSKILGYIVEYQKVGDEEWRRANHTPESCPETKYKVTGLRDGQTYKFRVLAVNAA 10823
Query: 1073 QES-----PKATGVFTTLQPGSSIPPYNT---------EVTETTIVITWTPAPRIGFKLG 1118
ES P+ V L+P I N + + +I P P++ +K
Sbjct: 10824 GESDPAHVPEPVLVKDRLEPPELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKE 10883
Query: 1119 VRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPT 1178
R + +A +VT + + +Y++ V + + V+ PP
Sbjct: 10884 DRDAP-TKARIDVTPVGSKLEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDKPGPPR 10942
Query: 1179 NLHL-EANPDTGVLTVSWERSTTPD---ITGYRITTTPTNGQQGNSLEEVVHADQSSCTF 1234
+L + E D+ LT W+ IT Y + Q + L + + S
Sbjct: 10943 DLEVSEIRKDSCYLT--WKEPLDDGGSVITNYVVERRDVASAQWSPLSAT--SKKKSHFA 10998
Query: 1235 DNLSPGLEYNVSVYTVK--------DDKESVPISDTIIPEVPQLTDLSFVDITDSSIGLR 1286
+L+ G +Y V + + + D + P P DL VD+ + + L
Sbjct: 10999 KHLNEGNQYLFRVAAENQYGRGPFVETPKPIKALDPLHPPGPP-KDLHHVDVDKTEVSLV 11057
Query: 1287 WTPLN---SSTIIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLIN 1343
W + S I GY V EG + F + VTGL+ G Y V
Sbjct: 11058 WNKPDRDGGSPITGY--LVEYQEEGTQDWIKFKTVTNLECVVTGLQQGKTYRFRVKAENI 11115
Query: 1344 GGESAPTTL----TQQTAVPPPTDLRFTNI------GPDTMR----VTWAPPPSIDLTNF 1389
G P T Q+ VPP +L I T+R + P P+ T
Sbjct: 11116 VGLGLPDTTIPIECQEKLVPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWT-- 11173
Query: 1390 LVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGT-EYVVSVSSVYEQHESTPLRGRQKTG 1448
S +K +E + + S + L T EY ++VS+ + T
Sbjct: 11174 -TDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEYQITVSNA----AGSKTVAVHLTV 11228
Query: 1449 LD---SPTG-IDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSI 1504
LD PTG I+ D+T T+ W P+ I + E R V S +S
Sbjct: 11229 LDVPGPPTGPINILDVTPEHMTISWQPPKDDGGSPVINYIVEKQDTRKDTWGVVSSGSSK 11288
Query: 1505 T---LTNLTPGTEYVVSIVALN------GREESPLLIGQQSTVSDVPRDLEVVAATPTSL 1555
T + +L G EYV + A N + +P + + + P V T +
Sbjct: 11289 TKLKIPHLQKGCEYVFRVRAENKIGVGPPLDSTPTVAKHKFSPPSPPGKPVVTDITENAA 11348
Query: 1556 LISWDAP-----AVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVY 1610
+SW P + YY TG V + + K T GL G Y V+
Sbjct: 11349 TVSWTLPKSDGGSPITGYYMERREVTGKWVRVNKTPIADLKFRVT--GLYEGNTYEFRVF 11406
Query: 1611 AVTGRGDSPASSKPISINYRTEIDKPS---QMQVTDVQDNSISVKWL----PSSSPVTGY 1663
A G S S I I P ++ D + + W SP+ GY
Sbjct: 11407 AENLAGLSKPSPSSDPIKACRPIKPPGPPINPKLKDKSRETADLVWTKPLSDGGSPILGY 11466
Query: 1664 RVTTTPKNGPGPTKTKTAGPD----QTEMTIEGLQPTVEYVVSVYAQNPSGESQP 1714
V PG + D Q + GL EY + A N GE +P
Sbjct: 11467 VVEC---QKPGTAQWNRINKDELIRQCAFRVPGLIEGNEYRFRIKAANIVGEGEP 11518
Score = 83.2 bits (204), Expect = 3e-15
Identities = 182/840 (21%), Positives = 295/840 (35%), Gaps = 117/840 (13%)
Query: 1338 VITLIN--GGESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAPPPS---IDLTNFLVR 1392
V+T N G A T+ P +L+ ++ D V W PP ++ N+++
Sbjct: 11903 VVTATNTAGSFVAYATVNVLDKPGPVRNLKIVDVSSDRCTVCWDPPEDDGGCEIQNYILE 11962
Query: 1393 YSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQ---KTGL 1449
K + S + +T L+ G EY+ V + + P + KT
Sbjct: 11963 KCETKRMV-WSTYSATVLTPGTTVTRLIEGNEYIFRVRAENKIGTGPPTESKPVIAKTKY 12021
Query: 1450 DSPTGIDFSDITANS---FTVHWIAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRN 1502
D P D ++T S TV W P +ITGY + +H + ++
Sbjct: 12022 DKPGRPDPPEVTKVSKEEMTVVWNPPEYDGGKSITGYFLEKKEKHSTRWVPVNKSAIPER 12081
Query: 1503 SITLTNLTPGTEYVVSIVALN-------GREESPLLIGQQSTVSDVPRDLEVVAATPTSL 1555
+ + NL P EY + A N P++ P + VV T S+
Sbjct: 12082 RMKVQNLLPDHEYQFRVKAENEIGIGEPSLPSRPVVAKDPIEPPGPPTNFRVVDTTKHSI 12141
Query: 1556 LISWDAP-----AVTVRYYRITYGETGGNSPVQEFTVPGS-----KSTATISGLKPGVDY 1605
+ W P A + Y + SP + + + + T++ L +Y
Sbjct: 12142 TLGWGKPVYDGGAPIIGYVVEMRPKIADASPDEGWKRCNAAAQLVRKEFTVTSLDENQEY 12201
Query: 1606 TITVYAVTGRG-DSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYR 1664
V A G PA K E KP ++ D S++ L R
Sbjct: 12202 EFRVCAQNQVGIGRPAELK--------EAIKPKEILEPPEIDLDASMRKLVIVRAGCPIR 12253
Query: 1665 VTTTPKNGPGPTKT-KTAGPDQTEMTIE-GLQPTVEYVV------------SVYAQNPSG 1710
+ + P P T + G D + L T+ ++V S+ NP+G
Sbjct: 12254 LFAIVRGRPAPKVTWRKVGIDNVVRKGQVDLVDTMAFLVIPNSTRDDSGKYSLTLVNPAG 12313
Query: 1711 ESQPLVQTAVTNIDRP-KGLAFTDVDVDSIKIAWESPQG----QVSRYRVTYSSPEDGIH 1765
E V V + P L +DV S ++W P+ QV+ Y V +
Sbjct: 12314 EKAVFVNVRVLDTPGPVSDLKVSDVTKTSCHVSWAPPENDGGSQVTHYIVEKREADRKTW 12373
Query: 1766 ELFPAPDGEEDTAELQGLRPGSEYTVSVVALHD-------DMESQPLIGTQSTAIPAPTD 1818
P+ ++ + + L PG+EY V A+++ D+ L + P
Sbjct: 12374 STV-TPEVKKTSFHVTNLVPGNEYYFRVTAVNEYGPGVPTDVPKPVLASDPLSEPDPPRK 12432
Query: 1819 LKFTQVTPTSLSAQWTPP--------NVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVV 1870
L+ T++T S + W PP + +T YR P ++ E ++ D S +VV
Sbjct: 12433 LEVTEMTKNSATLAWLPPLRDGGAKIDGYITSYREEEQPADR---WTEYSVVKDLS-LVV 12488
Query: 1871 SGLMVATKYEVSVYALKDTLTSRP--AQGVVTTLENVSPPRRARVTDAT----------- 1917
+GL KY+ V A S P A+GV E + PP+ T
Sbjct: 12489 TGLKEGKKYKFRVAARNAVGVSLPREAEGVYEAKEQLLPPKILMPEQITIKAGKKLRIEA 12548
Query: 1918 ----ETTITISWRT-KTETITGFQVDAVPANGQTP--IQRTIKPDVRSYTITGLQPGTDY 1970
+ T W+ + E +T + A+ + I+ + D Y++T
Sbjct: 12549 HVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGYYSLTAENSSG-- 12606
Query: 1971 KIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYII 2026
D + VV+DA P ++ + SL SW P + IT YI+
Sbjct: 12607 -------TDTQKIKVVVMDAPGPPQPPFDISDIDADACSL--SWHIPLEDGGSNITNYIV 12657
Query: 2027 KYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELP 2086
+ + S V T + L PG EY V A SEPL K + P
Sbjct: 12658 E-KCDVSRGDWVTALASVTKTSCRVGKLIPGQEYIFRVRAENRFGISEPLTSPKMVAQFP 12716
Score = 80.1 bits (196), Expect = 2e-14
Identities = 310/1425 (21%), Positives = 524/1425 (36%), Gaps = 261/1425 (18%)
Query: 780 LLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPIT 839
++P ++Y++ V ++ G + A D PT+D IV+ + P+
Sbjct: 7978 VVPDKEYVLRVRAVNAIGVSEPSEISENVVAKDPDCKPTIDLETHDIIVIEGEKLSIPVP 8037
Query: 840 GYRIVYSPSV----EGSSTELNLPETANSVTLS---DLQPGVQYNITIYAV--EENQEST 890
+R V P+V +G + + T + +S ++ V+ + IY + E S
Sbjct: 8038 -FRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSA 8096
Query: 891 PVVIQQETTGTPRSDTVPSP-RDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGE 949
I + G +P P +D++ ++T + W PPE G + V E
Sbjct: 8097 TASINVKVIG------LPGPCKDIKASDITKSSCKLTWEPPE--FDGGTPILHYVLERRE 8148
Query: 950 HGQR--LPI--SRNTFA-EVTGLSPGVTYYFKVFAVSH--GRE----SKPLTAQQTTKL- 997
G+R +P+ N + V L P Y+F+V AV+ G E P+ AQ +
Sbjct: 8149 AGRRTYIPVMSGENKLSWTVKDLIPNGEYFFRVKAVNKVGGGEYIELKNPVIAQDPKQPP 8208
Query: 998 DAPTNLQFVNETDSTVLVRWTPPR----AQITGY---RLTVGLTRRGQPRQYNVGPSVSK 1050
D P +++ N T + + W PP ++I GY ++ G R + ++ V +
Sbjct: 8209 DPPVDVEVHNPTAEAMTITWKPPLYDGGSKIMGYIIEKIAKGEERWKRCNEHLV--PILT 8266
Query: 1051 YPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPA 1110
Y + L+ EY + A A G+ +P + PP T + A
Sbjct: 8267 YTAKGLEEGKEYQFRVRA-------ENAAGIS---EPSRATPP--------TKAVDPIDA 8308
Query: 1111 PRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVL--RDGQERDAPIVN 1168
P++ + + +G E + S SGS P + ++ V+ + ++R AP+V
Sbjct: 8309 PKVILRTSLEVKRGDEIALDA-SISGSPY-----PTITWIKDENVIVPEEIKKRAAPLVR 8362
Query: 1169 KVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHAD 1228
+ + L P T L++ N ++G S V
Sbjct: 8363 RRKGEVQEEEPFVL---PLTQRLSID-------------------NSKKGESQLRVR--- 8397
Query: 1229 QSSCTFDNLSPGLEYNVSVYTVKDDK--ESVPISDTIIPEVPQLTDLSFVDITDSSIGLR 1286
D+L P ++ + + V++D P + +++ + F DI +S+ +
Sbjct: 8398 ------DSLRP--DHGLYMIKVENDHGIAKAPCTVSVLDTPGPPINFVFEDIRKTSVLCK 8449
Query: 1287 WTPL---NSSTIIGYRITVVAAGEGIPIFEDFVDSSV---GYYTVTGLEPGIDYDISVIT 1340
W P S II Y T+ + P E V +S Y+VT L G +Y V
Sbjct: 8450 WEPPLDDGGSEIINY--TLEKKDKTKPDSEWIVVTSTLRHCKYSVTKLIEGKEYLFRVRA 8507
Query: 1341 LINGGESAPTTLTQQTAVPP------PTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYS 1394
G P A P P ++ ++M V W P D + ++ Y
Sbjct: 8508 ENRFGPGPPCVSKPLVAKDPFGPPDAPDKPIVEDVTSNSMLVKWNEPK--DNGSPILGYW 8565
Query: 1395 PVKNEEDVAELS-ISPSDNAVVLTN---LLPGTEYVVSVSSVYEQHESTPLR----GRQK 1446
K E + S ++ S + N LL G YV V + ++ + P + K
Sbjct: 8566 LEKREVNSTHWSRVNKSLLNALKANVDGLLEGLTYVFRVCA---ENAAGPGKFSPPSDPK 8622
Query: 1447 TGLD--SPTGIDFSDITANSFT---VHWIAPR----ATITGYRIRHHPEHFSGRPREDRV 1497
T D SP G +T S T + W P I GY + + R
Sbjct: 8623 TAHDPISPPGPPIPRVTDTSSTTIELEWEPPAFNGGGEIVGYFVDKQLVGTNEWSRCTEK 8682
Query: 1498 PHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLI 1557
T+ + G +Y + + A+N E P Q TV++ P++ A + +
Sbjct: 8683 MIKVRQYTVKEIREGADYKLRVSAVNAAGEGPPGETQPVTVAE-PQE---PPAVELDVSV 8738
Query: 1558 SWDAPAVTVRYYRITYGETGGNSPVQEFTVP--------------GSKSTATISGL--KP 1601
+ + RI TG P + +T G+KS I K
Sbjct: 8739 KGGIQIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKDRVVIDNVGTKSELIIKDALRKD 8798
Query: 1602 GVDYTITVYAVTGRGDSPA------------SSKPISINYRTEIDKPSQMQVTDVQDNSI 1649
Y IT G + A KP+ N K + +D +D+
Sbjct: 8799 HGRYVITATNSCGSKFAAARVEVFDVPGPVLDLKPVVTNR-----KMCLLNWSDPEDDG- 8852
Query: 1650 SVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPS 1709
S +TG+ + K+ T + ++++ I GL EY V A+N
Sbjct: 8853 -------GSEITGFIIER--KDAKMHTWRQPIETERSKCDITGLLEGQEYKFRVIAKNKF 8903
Query: 1710 GESQPLVQTAVTNID------RPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDG 1763
G P+ + +D P+ L +T+ +I + W+ P R SP G
Sbjct: 8904 GCGPPVEIGPILAVDPLGPPTSPERLTYTERTKSTITLDWKEP-------RSNGGSPIQG 8956
Query: 1764 I---HELFPAPDGEEDTAEL--------QGLRPGSEYTVSVVALHDDMESQPLIGTQSTA 1812
PD E L + L Y V A+++ ES+P +
Sbjct: 8957 YIIEKRRHDKPDFERVNKRLCPTTSFLVENLDEHQMYEFRVKAVNEIGESEP-------S 9009
Query: 1813 IPAPTDLKFTQVTPT---SLSAQWTPPNVQLTGYRVRVTPKEKTG-PMKEINLAPDSSSV 1868
+P ++ +V PT LS + V+ G V + P + TG PM +I + + + +
Sbjct: 9010 LPLNVVIQDDEVPPTIKLRLSVRGDTIKVK-AGEPVHI-PADVTGLPMPKIEWSKNETVI 9067
Query: 1869 VV-SGLMVATKYEVS-------------VYALKDTLTSRPAQGVVTTLENV--------S 1906
+ + TK EVS V K T T + + + NV S
Sbjct: 9068 EKPTDALQITKEEVSRSEAKTELSIPKAVREDKGTYTVTASNRLGSVFRNVHVEVYDRPS 9127
Query: 1907 PPRRARVTDATETTITISWRTKTET----ITGFQVDAVPANGQTPIQRTIKPDV--RSYT 1960
PPR VTD + ++W + IT + +D A+ + + + Y
Sbjct: 9128 PPRNLAVTDIKAESCYLTWDAPLDNGGSEITHYVIDKRDASRKKAEWEEVTNTAVEKRYG 9187
Query: 1961 ITGLQPGTDYKIYL-----YTLNDNARSSPVVI-DASTAIDAPSNLRFLATTPNSLLVSW 2014
I L P Y+ + Y ++D +S VVI D P + LA T S+LVSW
Sbjct: 9188 IWKLIPNGQYEFRVRAVNKYGISDECKSDKVVIQDPYRLPGPPGKPKVLARTKGSMLVSW 9247
Query: 2015 QPP----RARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLE 2055
PP + ITGY ++ + GSP V R +T+ + G+E
Sbjct: 9248 TPPLDNGGSPITGYWLEKREEGSPYWSRV--SRAPITKVGLKGVE 9290
Score = 78.2 bits (191), Expect = 9e-14
Identities = 286/1430 (20%), Positives = 494/1430 (34%), Gaps = 241/1430 (16%)
Query: 690 QEVTRFDFTTTSTST---------------PVTSNTVTGET-------------TPFSPL 721
++ R +F TT+TST P+T+ + GE P P+
Sbjct: 14735 KQTQRVNFETTATSTILNINECVRSDSGPYPLTARNIVGEVGDVITIQVHDIPGPPTGPI 14794
Query: 722 VATSESVTEITASSFVVSWVSASD----TVSGFRVEYELSEEGDEPQYLDLPSTA--TSV 775
E+++ SW + +S + VE + D +++L +T T+
Sbjct: 14795 -----KFDEVSSDFVTFSWDPPENDGGVPISNYVVE---MRQTDSTTWVELATTVIRTTY 14846
Query: 776 NIPDLLPGRKY-----IVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVR 830
L G +Y N Y + + I++ P P P V V S+ +
Sbjct: 14847 KATRLTTGLEYQFRVKAQNRYGVGPGITSACIVANYPFKVPGPPGTPQVTAVTKDSMTIS 14906
Query: 831 WSRP----QAPITGYRIVYSPSVEGSSTELNLPETANSVTL-------SDLQPGVQYNIT 879
W P +PI GY VE L +T + + S L G+ Y
Sbjct: 14907 WHEPLSDGGSPILGYH------VERKERNGILWQTVSKALVPGNIFKSSGLTDGIAYEFR 14960
Query: 880 IYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESA----VT 935
+ A +S P + D P L +T VT+ W PE +T
Sbjct: 14961 VIAENMAGKSKPSKPSEPMLALDPIDPPGKPVPL---NITRHTVTLKWAKPEYTGGFKIT 15017
Query: 936 GYRVDVIPVNLPGEHGQRLPIS---RNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQ 992
Y V+ +LP + S N F V+GL+ Y F+V A + P +
Sbjct: 15018 SYIVE--KRDLPNGRWLKANFSNILENEFT-VSGLTEDAAYEFRVIAKNAAGAISPPSEP 15074
Query: 993 QTT-----KLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQP-RQYNVGP 1046
++AP V D+ +L +RL ++ R P +++
Sbjct: 15075 SDAITCRDDVEAPKIKVDVKFKDTVILKAG-------EAFRLEADVSGRPPPTMEWSKDG 15127
Query: 1047 SVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSI-------------PP 1093
+ + ++++ +LV K + T PG PP
Sbjct: 15128 KELEGTAKLEIKIADFSTNLVN-KDSTRRDSGAYTLTATNPGGFAKHIFNVKVLDRPGPP 15186
Query: 1094 YN----TEVTETTIVITW-TPAPRIGFKLGVRPSQGGEAPREVTSDSGSIV------VSG 1142
TEVT V++W P G K+ Q E R ++ S V V+
Sbjct: 15187 EGPLAVTEVTSEKCVLSWFPPLDDGGAKIDHYIVQKRETSRLAWTNVASEVQVTKLKVTK 15246
Query: 1143 LTPGVEYVYTIQVLRD---GQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLT-----VS 1194
L G EY++ + + G+ ++ V V P PP NP+ +T V
Sbjct: 15247 LLKGNEYIFRVMAVNKYGVGEPLESEPV-LAVNPYGPPDP---PKNPEVTTITKDSMVVC 15302
Query: 1195 W---ERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVK 1251
W + +I Y + GQ+ + D L+ G EY +
Sbjct: 15303 WGHPDSDGGSEIINYIVERRDKAGQRWIKCNKKTLTD-LRYKVSGLTEGHEYEFRIMAEN 15361
Query: 1252 DDKESVP--------ISDTIIPEVPQLTDLSFVDITDSSIGLRWT-PL--NSSTIIGYRI 1300
S P DT+ P + +D + SSI + W P+ S I GY +
Sbjct: 15362 AAGISAPSPTSPFYKACDTVFKPGPP-GNPRVLDTSRSSISIAWNKPIYDGGSEITGYMV 15420
Query: 1301 TVVAAGEG-IPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAP-----TTLTQ 1354
+ E I YT+TGL +Y I + + + G P T +
Sbjct: 15421 EIALPEEDEWQIVTPPAGLKATSYTITGLTENQEYKIRIYAMNSEGLGEPALVPGTPKAE 15480
Query: 1355 QTAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNE------------EDV 1402
+PP +L D +V +I L + P+K E +
Sbjct: 15481 DRMLPPEIEL-----DADLRKVV-----TIRACCTLRLFVPIKGRPAPEVKWARDHGESL 15530
Query: 1403 AELSISPSDNAVVL----TNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFS 1458
+ SI + + +L N +Y+++V + +S + R P +
Sbjct: 15531 DKASIESTSSYTLLIVGNVNRFDSGKYILTVEN-SSGSKSAFVNVRVLDTPGPPQDLKVK 15589
Query: 1459 DITANSFTVHWIAPRATITGYRIRHH--PEHFSGRPREDRVPHS--RNSITLTNLTPGTE 1514
++T S T+ W P G +I+++ + S R V + + S + L G
Sbjct: 15590 EVTKTSVTLTWDPPLLD-GGSKIKNYIVEKRESTRKAYSTVATNCHKTSWKVDQLQEGCS 15648
Query: 1515 YVVSIVALN----GREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAP----AVTV 1566
Y ++A N G + S P + ++ T S+ +SW+ P +
Sbjct: 15649 YYFRVLAENEYGIGLPAETAESVKASERPLPPGKITLMDVTRNSVSLSWEKPEHDGGSRI 15708
Query: 1567 RYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPIS 1626
Y + G + TV + ATI+GL G +Y+ V A +G S +
Sbjct: 15709 LGYIVEMQTKGSDKWATCATV--KVTEATITGLIQGEEYSFRVSAQNEKGISDPRQLSVP 15766
Query: 1627 INYRTEIDKP------SQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKT 1680
+ + + P + V +D + V ++ +P + P +T
Sbjct: 15767 VIAKDLVIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLK-----QTTR 15821
Query: 1681 AGPDQTE----MTIEGL--QPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRP----KGLA 1730
+ TE +TI+ + YVV + N +GE+ + V +D+P +
Sbjct: 15822 VNAESTENNSLLTIKDACREDVGHYVVKL--TNSAGEAIETLNVIV--LDKPGPPTGPVK 15877
Query: 1731 FTDVDVDSIKIAWESPQ----GQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPG 1786
+V DSI ++W P+ ++ Y V ++ A T + L+ G
Sbjct: 15878 MDEVTADSITLSWGPPKYDGGSSINNYIVEKRDTSTTTWQIVSATVA-RTTIKACRLKTG 15936
Query: 1787 SEYTVSVVALH-----DDMESQPLIGTQSTAIPAPTDLK-FTQVTPTSLSAQWTPP---- 1836
EY + A + + S+P + +P P T + S+ QW P
Sbjct: 15937 CEYQFRIAAENRYGKSTYLNSEPTVAQYPFKVPGPPGTPVVTLSSRDSMEVQWNEPISDG 15996
Query: 1837 NVQLTGYRVRVTPKEKTGPM-KEINLAP-DSSSVVVSGLMVATKYEVSVYALKDTLTSRP 1894
++ GY + KE+ + ++N P + +GL +YE V A +P
Sbjct: 15997 GSRVIGYHLE--RKERNSILWVKLNKTPIPQTKFKTTGLEEGVEYEFRVSAENIVGIGKP 16054
Query: 1895 AQ--GVVTTLENVSPPRRARVTDATETTITISWRTKT----ETITGFQVD 1938
++ + PP R T ++T+ W+ T ITG+ V+
Sbjct: 16055 SKVSECYVARDPCDPPGRPEAIIVTRNSVTLQWKKPTYDGGSKITGYIVE 16104
Score = 75.1 bits (183), Expect = 8e-13
Identities = 286/1351 (21%), Positives = 472/1351 (34%), Gaps = 234/1351 (17%)
Query: 797 GEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ----APITGYRIVYSPSVEGS 852
G +++ + P P D V ++ S + W P + IT Y +
Sbjct: 10924 GSKTVSVKVLVLDKPGPPRDLEVSEIRKDSCYLTWKEPLDDGGSVITNYVVERRDVASAQ 10983
Query: 853 STELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRD 912
+ L+ S L G QY + A + V + P+D
Sbjct: 10984 WSPLSATSKKKSHFAKHLNEGNQYLFRVAAENQYGRGPFVETPKPIKALDPLHPPGPPKD 11043
Query: 913 LQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPVNLPGEHGQRLPISRNTFAE----V 964
L V+V +V+++W P+ S +TGY V+ E G + I T V
Sbjct: 11044 LHHVDVDKTEVSLVWNKPDRDGGSPITGYLVEY------QEEGTQDWIKFKTVTNLECVV 11097
Query: 965 TGLSPGVTYYFKVFA---VSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPR 1021
TGL G TY F+V A V G + + KL P+ V + V+ T R
Sbjct: 11098 TGLQQGKTYRFRVKAENIVGLGLPDTTIPIECQEKLVPPSVELDVKLIEGLVVKAGTTVR 11157
Query: 1022 --AQITGYRL-TVGLTRRGQPRQYNVGPSV------SKYPLRNL--QPASEYTVSLVAIK 1070
A I G + T T G + + +V S ++N + EY +++
Sbjct: 11158 FPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEYQITV---- 11213
Query: 1071 GNQESPKATGVFTTLQ--PGSSIPPYNT-EVTETTIVITWTPAPRIGFKLGVRPSQGGEA 1127
N K V T+ PG P N +VT + I+W P P G +
Sbjct: 11214 SNAAGSKTVAVHLTVLDVPGPPTGPINILDVTPEHMTISWQP-----------PKDDGGS 11262
Query: 1128 P--------REVTSDSGSIVVSG----------LTPGVEYVYTIQV---LRDGQERDA-P 1165
P ++ D+ +V SG L G EYV+ ++ + G D+ P
Sbjct: 11263 PVINYIVEKQDTRKDTWGVVSSGSSKTKLKIPHLQKGCEYVFRVRAENKIGVGPPLDSTP 11322
Query: 1166 IVNK-VVTPLSPPTNLHLEANPDTGVLTVSWERSTTPD---ITGY------------RIT 1209
V K +P SPP + + TVSW + ITGY R+
Sbjct: 11323 TVAKHKFSPPSPPGK-PVVTDITENAATVSWTLPKSDGGSPITGYYMERREVTGKWVRVN 11381
Query: 1210 TTP--------TNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISD 1261
TP T +GN+ E V A+ NL+ + + S +K + PI
Sbjct: 11382 KTPIADLKFRVTGLYEGNTYEFRVFAE-------NLAGLSKPSPSSDPIKACR---PIKP 11431
Query: 1262 TIIPEVPQLTDLSFVDITDSSIGLRWT-PLNS--STIIGYRITVVAAG--EGIPIFEDFV 1316
P P+L D S + L WT PL+ S I+GY + G + I +D +
Sbjct: 11432 PGPPINPKLKDKS-----RETADLVWTKPLSDGGSPILGYVVECQKPGTAQWNRINKDEL 11486
Query: 1317 DSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAV-----PPPTDLRFTNIGP 1371
+ V GL G +Y + GE P L + PP +L T
Sbjct: 11487 IRQCAF-RVPGLIEGNEYRFRIKAANIVGEGEPRELAESVIAKDILHPPEVELDVTCRDV 11545
Query: 1372 DTMRVTWA----------PPPSIDLTN---FLVRYSPVKNEEDV--AELSISPSDNAVVL 1416
T+RV P P I T LVR V +D+ EL I + A
Sbjct: 11546 ITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRA--- 11602
Query: 1417 TNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSP---TGIDFSDITANSFTVHWIAPR 1473
+Y++S + + + + LD P + +++T + T+ W P
Sbjct: 11603 ----DHGKYIISAKNSSGHAQGSAI----VNVLDRPGPCQNLKVTNVTKENCTISWENPL 11654
Query: 1474 ----ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNG----- 1524
+ IT + + + + G R + NL EY + A N
Sbjct: 11655 DNGGSEITNFIVEYRKPNQKGWSIVASDVTKR--LIKANLLANNEYYFRVCAENKVGVGP 11712
Query: 1525 --REESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYG---ETGGN 1579
++P+L P +L + T + + W P ++Y G+
Sbjct: 11713 TIETKTPILAINPIDRPGEPENLHIADKGKTFVYLKWRRPDYDGGSPNLSYHVERRLKGS 11772
Query: 1580 SPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASS--KPISINYRTEIDKPS 1637
+ K T + + V+ I + V + + S K + + ++ KP
Sbjct: 11773 DDWERVHKGSIKETHYM--VDRCVENQIYEFRVQTKNEGGESDWVKTEEVVVKEDLQKP- 11829
Query: 1638 QMQVTDVQDNSIS-VKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMT------I 1690
V D +S V + + + R+ + P P T D T++T I
Sbjct: 11830 ------VLDLKLSGVLTVKAGDTI---RLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKI 11880
Query: 1691 EGLQPTVEYVVSVYAQNPSGE--------SQPLVQTAVTNI-DRP---KGLAFTDVDVDS 1738
+ + ++ ++ ++ G+ + V A N+ D+P + L DV D
Sbjct: 11881 DTRADSSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATVNVLDKPGPVRNLKIVDVSSDR 11940
Query: 1739 IKIAWESPQG----QVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSV- 1793
+ W+ P+ ++ Y + + + + A T + L G+EY V
Sbjct: 11941 CTVCWDPPEDDGGCEIQNYILEKCETKRMVWSTYSATVLTPGTTVTR-LIEGNEYIFRVR 11999
Query: 1794 ----VALHDDMESQPLIGTQSTAIPA-PTDLKFTQVTPTSLSAQWTPPNVQ----LTGYR 1844
+ ES+P+I P P + T+V+ ++ W PP +TGY
Sbjct: 12000 AENKIGTGPPTESKPVIAKTKYDKPGRPDPPEVTKVSKEEMTVVWNPPEYDGGKSITGYF 12059
Query: 1845 VRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKD------TLTSRPAQGV 1898
+ K T + A + V L+ +Y+ V A + +L SRP
Sbjct: 12060 LEKKEKHSTRWVPVNKSAIPERRMKVQNLLPDHEYQFRVKAENEIGIGEPSLPSRPVVAK 12119
Query: 1899 VTTLENVSPPRRARVTDATETTITISWRTKT----ETITGFQV-------DAVPANGQTP 1947
+E PP RV D T+ +IT+ W I G+ V DA P G
Sbjct: 12120 -DPIEPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAPIIGYVVEMRPKIADASPDEGWKR 12178
Query: 1948 IQRTIKPDVRSYTITGLQPGTDYKIYLYTLN 1978
+ + +T+T L +Y+ + N
Sbjct: 12179 CNAAAQLVRKEFTVTSLDENQEYEFRVCAQN 12209
Score = 71.2 bits (173), Expect = 1e-11
Identities = 350/1644 (21%), Positives = 556/1644 (33%), Gaps = 296/1644 (18%)
Query: 628 IQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISI 684
+ W +P+ S I+ Y++ R + W T + T++GL G Y ++ +
Sbjct: 10263 LTWFSPEDDGGSPITNYVIEKRESDRRA-WTPVTYTVTRQNATVQGLIQGKAYFFRIAAE 10321
Query: 685 QQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSAS 744
G F TS + + T P P V E+T ++ ++W
Sbjct: 10322 NSIGMGP-----FVETSEALVIREPI----TVPERP---EDLEVKEVTKNTVTLTWNPPK 10369
Query: 745 DTVSGFRVEYELSEE--GDEPQYLDLPSTATS--VNIPDLLPGRKYIVNVYQISEDGEQS 800
+ Y L G E + S + L G Y V ++ G+
Sbjct: 10370 YDGGSEIINYVLESRLIGTEKFHKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGK 10429
Query: 801 LILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPE 860
T T D PT+ + +R A Y P V E ++ E
Sbjct: 10430 PSFCTKPITCKDELAPPTLHLDFRDKLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLE 10489
Query: 861 TANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQET---TGTPRSDTVPSPRD----L 913
+ T P I A + VV++ T G + + V P +
Sbjct: 10490 --DDRTHIKTTPATLALEKIKAKRSDSGKYCVVVENSTGSRKGFCQVNVVDRPGPPVGPV 10547
Query: 914 QFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPGEHGQRLPI---SRNTFAEVTG 966
F EVT + I W PP S +T Y ++ V +P+ S T +V+
Sbjct: 10548 SFDEVTKDYMVISWKPPLDDGGSKITNYIIEKKEVG----KDVWMPVTSASAKTTCKVSK 10603
Query: 967 LSPGVTYYFKVFAVSHGRESKPLTAQQTTKLD------APTNLQFVNETDSTVLVRWTPP 1020
L G Y F++ A + S PL + D AP T + LV W P
Sbjct: 10604 LLEGKDYIFRIHAENLYGISDPLVSDSMKAKDRFRVPDAPDQPIVTEVTKDSALVTWNKP 10663
Query: 1021 R---AQITGYRLTVGLTRRGQPRQYNVGP--SVSKYPLRNLQPASEYTVSLVA---IKGN 1072
IT Y L T + + P +K+ + +L +Y + A I
Sbjct: 10664 HDGGKPITNYILEKRETMSKRWARVTKDPIHPYTKFRVPDLLEGCQYEFRVSAENEIGIG 10723
Query: 1073 QESPKATGVFTTLQPGSSIPPYNTEVTETT---IVITWTPAPRIGFKLGVRPSQGGEAPR 1129
SP + VF PP N E +TT + +TW P PR
Sbjct: 10724 DPSPPSKPVFAKDPIAKPSPPVNPEAIDTTCNSVDLTWQP------------------PR 10765
Query: 1130 EVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTG 1189
D GS ++ Y+ Q + D + R A N E+ P+T
Sbjct: 10766 H---DGGSKILG-------YIVEYQKVGDEEWRRA--------------NHTPESCPETK 10801
Query: 1190 VLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPG---LEYNVS 1246
T +R+ G+ + H + D L P L+ N++
Sbjct: 10802 YKVTGLRDGQTYK---FRVLAVNAAGES-----DPAHVPEPVLVKDRLEPPELILDANMA 10853
Query: 1247 VYTVKDDKESVPISDT-----IIPEVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGYRIT 1301
++ + + DT II VP F +T W + RI
Sbjct: 10854 ------REQHIKVGDTLRLSAIIKGVP------FPKVT-------WKKEDRDAPTKARID 10894
Query: 1302 VVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAVPPP 1361
V G + I + G Y++T P +SV L+ PP
Sbjct: 10895 VTPVGSKLEI-RNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDKPG------------PP 10941
Query: 1362 TDLRFTNIGPDTMRVTWAPPPSID---LTNFLVRYSPVKNEEDVAELSISPSDNAVVLTN 1418
DL + I D+ +TW P +TN++V V + + + LS + + +
Sbjct: 10942 RDLEVSEIRKDSCYLTWKEPLDDGGSVITNYVVERRDVASAQ-WSPLSATSKKKSHFAKH 11000
Query: 1419 LLPGTEYVVSVSSVYEQHESTPLRGRQKT--GLDS------PTGIDFSDITANSFTVHWI 1470
L G +Y+ V++ Q+ P K LD P + D+ ++ W
Sbjct: 11001 LNEGNQYLFRVAAE-NQYGRGPFVETPKPIKALDPLHPPGPPKDLHHVDVDKTEVSLVWN 11059
Query: 1471 APR----ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN--- 1523
P + ITGY + + E + V + +T L G Y + A N
Sbjct: 11060 KPDRDGGSPITGYLVEYQEEGTQDWIKFKTVTNLE--CVVTGLQQGKTYRFRVKAENIVG 11117
Query: 1524 -GREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPV 1582
G ++ + I Q + VP +E+ L++ TVR+ I G P
Sbjct: 11118 LGLPDTTIPIECQEKL--VPPSVELDVKLIEGLVVK---AGTTVRFPAIIRGVP---VPT 11169
Query: 1583 QEFTVPGSK---------------STATISGL--KPGVDYTITVYAVTGRGDSPASSKPI 1625
++T GS+ S TI + +Y ITV + A SK +
Sbjct: 11170 AKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEYQITV-------SNAAGSKTV 11222
Query: 1626 SINYRTEIDKPSQ----MQVTDVQDNSISVKWLP----SSSPVTGYRVTT--TPKNGPGP 1675
+++ T +D P + + DV +++ W P SPV Y V T K+ G
Sbjct: 11223 AVHL-TVLDVPGPPTGPINILDVTPEHMTISWQPPKDDGGSPVINYIVEKQDTRKDTWGV 11281
Query: 1676 TKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDR------PKGL 1729
++G +T++ I LQ EYV V A+N G PL T + P
Sbjct: 11282 V---SSGSSKTKLKIPHLQKGCEYVFRVRAENKIGVGPPLDSTPTVAKHKFSPPSPPGKP 11338
Query: 1730 AFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQ----GLRP 1785
TD+ ++ ++W P+ Y + + + + A+L+ GL
Sbjct: 11339 VVTDITENAATVSWTLPKSDGGSPITGYYMERREVTGKWVRVN-KTPIADLKFRVTGLYE 11397
Query: 1786 GSEYTVSVVALH------DDMESQPLIGTQSTAIPA-PTDLKFTQVTPTSLSAQWTPP-- 1836
G+ Y V A + S P+ + P P + K + + WT P
Sbjct: 11398 GNTYEFRVFAENLAGLSKPSPSSDPIKACRPIKPPGPPINPKLKDKSRETADLVWTKPLS 11457
Query: 1837 --NVQLTGYRVRVTPKEKTGPMKEINLAP--DSSSVVVSGLMVATKYEVSVYALKDTLTS 1892
+ GY V K T IN + V GL+ +Y + A
Sbjct: 11458 DGGSPILGYVVE-CQKPGTAQWNRINKDELIRQCAFRVPGLIEGNEYRFRIKAANIVGEG 11516
Query: 1893 RP---AQGVVTTLENVSPPR-------RARVTDATETTITISWRTK-------TETITG- 1934
P A+ V+ + + PP R +T TI I R K T T G
Sbjct: 11517 EPRELAESVIAK-DILHPPEVELDVTCRDVITVRVGQTIRILARVKGRPEPDITWTKEGK 11575
Query: 1935 -----FQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVID 1989
+VD + + +Q IK VR+ Y I + +A+ S +V
Sbjct: 11576 VLVREKRVDLIQDLPRVELQ--IKEAVRA-------DHGKYIISAKNSSGHAQGSAIV-- 11624
Query: 1990 ASTAIDAP---SNLRFLATTPNSLLVSWQPP----RARITGYIIKYEKPGSPPREVVPRP 2042
+D P NL+ T + +SW+ P + IT +I++Y KP +V
Sbjct: 11625 --NVLDRPGPCQNLKVTNVTKENCTISWENPLDNGGSEITNFIVEYRKPNQKGWSIV--- 11679
Query: 2043 RPGVTEATI-TGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELPQLVTLPHPNLHGPEI 2101
VT+ I L EY V A +N P I K P L P PE
Sbjct: 11680 ASDVTKRLIKANLLANNEYYFRVCA-ENKVGVGPTIETK----TPILAINPIDRPGEPEN 11734
Query: 2102 LDVPSTVQKTPFV--THPGYDTGN 2123
L + + ++ P YD G+
Sbjct: 11735 LHIADKGKTFVYLKWRRPDYDGGS 11758
Score = 67.8 bits (164), Expect = 1e-10
Identities = 172/864 (19%), Positives = 306/864 (35%), Gaps = 155/864 (17%)
Query: 1325 VTGLEPGIDYDISVITLINGGESAPT------TLTQQTAVPPPTDLRFTNIGPDTMRVTW 1378
VT L G +Y V + G P L T PPT L T++ ++M + W
Sbjct: 19572 VTKLLKGNEYIFRVTGVNKYGVGEPLESVAIKALDPFTVPSPPTSLEITSVTKESMTLCW 19631
Query: 1379 APPPS---IDLTNFLVRYSPVKNEEDVAELSISP-SDNAVVLTNLLPGTEYVVSV----- 1429
+ P S +++ +++ KN ++ P D V T L G EY V
Sbjct: 19632 SRPESDGGSEISGYIIERRE-KNSLRWVRVNKKPVYDLRVKSTGLREGCEYEYRVYAENA 19690
Query: 1430 SSVYEQHESTPL-RGRQKTGLDS-PTGIDFSDITANSFTVHWIAP----RATITGYRIRH 1483
+ + E++PL R L S P+ D + T+ W+ P A ITGY + +
Sbjct: 19691 AGLSLPSETSPLIRAEDPVFLPSPPSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEY 19750
Query: 1484 HPEHFSGRPREDRVPHSRNS-ITLTNLTPGTEYVVSIVALN-----------------GR 1525
+ + + R + T++ LT G EYV + ++N R
Sbjct: 19751 --KKSDDTDWKTSIQSLRGTEYTISGLTTGAEYVFRVKSVNKVGASDPSDSSDPQIAKER 19808
Query: 1526 EESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEF 1585
EE PL S++ + L V A ++ + + V + + + + + +
Sbjct: 19809 EEEPLF----DIDSEMRKTLIVKAGASFTMTVPFRGRPVP----NVLWSKPDTDLRTRAY 19860
Query: 1586 T-VPGSKSTATI--SGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVT 1642
S+++ TI + YT+T+ V A+S + + P+ + V
Sbjct: 19861 VDTTDSRTSLTIENANRNDSGKYTLTIQNVLS-----AASLTLVVKVLDTPGPPTNITVQ 19915
Query: 1643 DVQDNSISVKW-LPSS---SPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVE 1698
DV S + W +P + +PV Y + + T ++ + LQ
Sbjct: 19916 DVTKESAVLSWDVPENDGGAPVKNYHIEKREASKKAWVSV-TNNCNRLSYKVTNLQEGAI 19974
Query: 1699 YVVSVYAQNPSGESQPLVQTAVTNIDR----PKGLAFTDVDVDSIKIAWESPQGQVSRYR 1754
Y V +N G P I P+ L T + DS+ + W P+
Sbjct: 19975 YYFRVSGENEFGVGIPAETKEGVKITEKPSPPEKLGVTSISKDSVSLTWLKPEHDGGSRI 20034
Query: 1755 VTY--SSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTA 1812
V Y + E G + + GLR SEY V A E+Q
Sbjct: 20035 VHYVVEALEKGQKNWVKCAVAKSTHHVVSGLRENSEYFFRVFA-----ENQ-------AG 20082
Query: 1813 IPAPTDLKFTQVTPTSLSAQWTPPNVQL-----------TGYRVRVTPKEKTGPMKEINL 1861
+ P +L + P + Q PP + + G ++V P+ ++ L
Sbjct: 20083 LSDPREL----LLPVLIKEQLEPPEIDMKNFPSHTVYVRAGSNLKVDIPISGKPLPKVTL 20138
Query: 1862 APD----------SSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGV------VTTLENV 1905
+ D ++ + L + K V+ A + +T+ + G + L+
Sbjct: 20139 SRDGVPLKATMRFNTEITAENLTINLKESVTADAGRYEITAANSSGTTKAFINIVVLDRP 20198
Query: 1906 SPPR-RARVTDATETTITISWR---------------TKTETITGFQVDAVPANGQTPIQ 1949
PP ++D TE ++T+ W K ET T AV +
Sbjct: 20199 GPPTGPVVISDITEESVTLKWEPPKYDGGSQVTNYILLKRETST-----AVWTEVSATVA 20253
Query: 1950 RTIKPDVRSYTITGLQPGTDYKIYL-----YTLNDNARSSPVVIDASTAIDAPSNLRFLA 2004
RT+ + L G +Y+ + + ++D+ S+ V + P + ++
Sbjct: 20254 RTM------MKVMKLTTGEEYQFRIKAENRFGISDHIDSACVTVKLPYTTPGPPSTPWVT 20307
Query: 2005 -TTPNSLLVSWQPP----RARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTE 2059
T S+ V W P + + GY ++ + S + + T +T + G
Sbjct: 20308 NVTRESITVGWHEPVSNGGSAVVGYHLEMKDRNSILWQKANKLVIRTTHFKVTTISAGLI 20367
Query: 2060 YTIYVIAL------KNNQKSEPLI 2077
Y V A K + SEP++
Sbjct: 20368 YEFRVYAENAAGVGKPSHPSEPVL 20391
Score = 65.1 bits (157), Expect = 8e-10
Identities = 102/477 (21%), Positives = 189/477 (39%), Gaps = 56/477 (11%)
Query: 628 IQWNAPQP---SHISKYILRWRPKNSVGRWKEAT-IPGHLNSYTIKGLKPGVVYEGQLIS 683
+ W P+ S ++ YI+ R + RW +P + Y GL G+ YE ++ +
Sbjct: 23578 LTWYPPEDDGGSQVTGYIVE-RKEVRADRWVRVNKVPVTMTRYRSTGLTEGLEYEHRVTA 23636
Query: 684 IQQYGHQEVTRFDFTTTSTSTPVTS-NTVTGETTPFSPLVATSESVTEITASSFVVSWVS 742
I G + +R S P+ + + + P +P VT+ T +S ++W
Sbjct: 23637 INARGSGKPSR-------PSKPIVAMDPIAPPGKPQNP------RVTDTTRTSVSLAWSV 23683
Query: 743 ASDT----VSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDG- 797
D V+G+ +E + ++ + + P+ + L G +Y V + G
Sbjct: 23684 PEDEGGSKVTGYLIEMQKVDQHEWTKCNTTPTKIREYTLTHLPQGAEYRFRVLACNAGGP 23743
Query: 798 -EQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWS---RPQAPITGYRI-VYSPSVEGS 852
E + + T + T PD +D+ I VR R PI G + + EG
Sbjct: 23744 GEPAEVPGTVKVTEMLEYPDYELDERYQEGIFVRQGGVIRLTIPIKGKPFPICKWTKEGQ 23803
Query: 853 STE----LNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVP 908
+ ET + + + G + +E V I+ G+P S P
Sbjct: 23804 DISKRAMIATSETHTELVIKEADRGDSGTYDL-VLENKCGKKAVYIKVRVIGSPNSPEGP 23862
Query: 909 SPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEV 964
L++ ++ V + W PP + + GY ++ V + + R T V
Sbjct: 23863 ----LEYDDIQVRSVRVSWRPPADDGGADILGYILERREVPKAAWYTIDSRV-RGTSLVV 23917
Query: 965 TGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTN--------LQFVNETDSTVLVR 1016
GL V Y+F+V A + SKPL +++ P N + ++ T S+V +
Sbjct: 23918 KGLKENVEYHFRVSAENQFGISKPLKSEEPVTPKTPLNPPEPPSNPPEVLDVTKSSVSLS 23977
Query: 1017 WTPPR----AQITGYRLTVGLTRRGQPRQYN-VGPSVSKYPLRNLQPASEYTVSLVA 1068
W+ P+ +++TGY + T + ++N + + Y + L P +EY ++A
Sbjct: 23978 WSRPKDDGGSRVTGYYIERKETSTDKWVRHNKTQITTTMYTVTGLVPDAEYQFRIIA 24034
Score = 60.1 bits (144), Expect = 3e-08
Identities = 177/822 (21%), Positives = 289/822 (35%), Gaps = 149/822 (18%)
Query: 1360 PPTDLRFTNIGPDTMRVTWAPPPS---IDLTNFLVRYSPVKNEEDVAELSISPSDNAVVL 1416
P +L T + + W P + + ++V +K + V + S V
Sbjct: 6720 PVRNLEVTETFDGEVSLAWEEPLTDGGSKIIGYVVERRDIKRKTWVLATDRAESCEFTVT 6779
Query: 1417 TNLLPGTEYVVSVSS-----VYEQHES-TPLRGRQKTGLDSPT-GIDFSDITANSFTVHW 1469
G EY+ VS+ E E+ P+ R K + P + +D+ ++ W
Sbjct: 6780 GLQKGGVEYLFRVSARNRVGTGEPVETDNPVEARSKYDVPGPPLNVTITDVNRFGVSLTW 6839
Query: 1470 IAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGR 1525
P A IT Y I + V S T+T++ G EY + R
Sbjct: 6840 EPPEYDGGAEITNYVIELRDKTSIRWDTAMTVRAEDLSATVTDVVEGQEYSFRV-----R 6894
Query: 1526 EESPLLIGQQSTVSDV------------PRDLEVVAATPTSLLISWDAP----AVTVRYY 1569
++ + +G+ S + P +L T +S+ + W+ P + Y
Sbjct: 6895 AQNRIGVGKPSAATPFVKVADPIERPSPPVNLTSSDQTQSSVQLKWEPPLKDGGSPILGY 6954
Query: 1570 RITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINY 1629
I E G ++ ++ + T ++GL+ G Y V A G S S +
Sbjct: 6955 IIERCEEGKDNWIRCNMKLVPELTYKVTGLEKGNKYLYRVSAENKAGVSDPSEILGPLTA 7014
Query: 1630 RTEIDKPSQMQVTDVQDNSISVKWLPSSS--PVTGYRVTTTPKNGPGPTKTKTAGPDQTE 1687
+P+ M ++ +D + P + P TGY P PT T G E
Sbjct: 7015 DDAFVEPT-MDLSAFKDGLEVIVPNPITILVPSTGY---------PRPTATWCFGDKVLE 7064
Query: 1688 ----MTIEGLQPTVEYVVSVYAQNPSG----ESQPLVQTAVTNID--------RPKGLAF 1731
+ ++ L E V+S ++ G + + V+T ID PK L F
Sbjct: 7065 TGDRVKMKTLSAYAELVISPSERSDKGIYTLKLENRVKTISGEIDVNVIARPSAPKELKF 7124
Query: 1732 TDVDVDSIKIAWESPQ----GQVSRY--------RVTYSSPEDGIHEL-FPAPDGEEDTA 1778
D+ DS+ + WE P ++ Y R T++ D + +L F PD
Sbjct: 7125 GDITKDSVHLTWEPPDDDGGSPLTGYVVEKREVSRKTWTKVMDFVTDLEFTVPD------ 7178
Query: 1779 ELQGLRPGSEYTVSVVALHDDMESQPL-------IGTQSTAIPAPTDLKFTQVTPTSLSA 1831
L G EY V A + +P + T +T P ++K+ T S+
Sbjct: 7179 ----LVQGKEYLFKVCARNKCGPGEPAYVDEPVNMSTPATVPDPPENVKWRDRTANSIFL 7234
Query: 1832 QWTPP----NVQLTGYRVRVTPKEKTGPMKEINLAPD--SSSVVVSGLMVATKYEVSVYA 1885
W PP ++ GY V P+ G K + + + V+GL Y V A
Sbjct: 7235 TWDPPKNDGGSRIKGYIVERCPR---GSDKWVACGEPVAETKMEVTGLEEGKWYAYRVKA 7291
Query: 1886 LKDTLTSRPAQGVVTTLENVSPPRRARVTDATETT-----------ITISWRTKTE---T 1931
L S+P++ P + D E +T+ TK E T
Sbjct: 7292 LNRQGASKPSR----------PTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPAT 7341
Query: 1932 ITGFQVDAVPANGQTPIQRTIKPDVR----------SYTITGLQPGTDYKIYLYTLNDNA 1981
+TG P T +K D R + TI + + +N
Sbjct: 7342 VTG---KPEPKITWTKADMILKQDKRITIENVPKKSTVTIVDSKRSDTGTYIIEAVNVCG 7398
Query: 1982 RSSPVV-IDASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPR 2036
R++ VV ++ P+ T S L++W PPR ++IT Y+++ S
Sbjct: 7399 RATAVVEVNVLDKPGPPAAFDITDVTNESCLLTWNPPRDDGGSKITNYVVERRATDS--- 7455
Query: 2037 EVVPRPRPGV--TEATITGLEPGTEYTIYVIALKNNQKSEPL 2076
EV + V T T L P EY V A EP+
Sbjct: 7456 EVWHKLSSTVKDTNFKATKLIPNKEYIFRVAAENMYGVGEPV 7497
Score = 58.9 bits (141), Expect = 6e-08
Identities = 325/1703 (19%), Positives = 588/1703 (34%), Gaps = 267/1703 (15%)
Query: 611 PVEVFITETPSQP-----------NSHPIQWNAPQPS---HISKYILRWRPKNSVGRWKE 656
P+ V PS+P +S + W+ P+ + I+ Y + R + S WK
Sbjct: 21276 PITVITLGPPSKPKGPIRFDEIKADSVILSWDVPEDNGGGEITCYSIEKR-ETSQTNWKM 21334
Query: 657 ATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETT 716
++ + L Y+ ++ + +YG S P+ S+ + +
Sbjct: 21335 VCSSVARTTFKVPNLVKDAEYQFRVRAENRYG-------------VSQPLVSSIIVAKHQ 21381
Query: 717 PFSPLVATSESVTEITASSFVVSW----VSASDTVSGFRVEYELSEEGDEPQYLDLPSTA 772
P + +T+ ++W V+GF VE + + P +
Sbjct: 21382 FRIPGPPGKPVIYNVTSDGMSLTWDAPVYDGGSEVTGFHVEKKERNSILWQKVNTSPISG 21441
Query: 773 TSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDP--TVDQVDDT--SIV 828
L+ G Y VY + G S S+ T +P DP T D +D T +I
Sbjct: 21442 REYRATGLVEGLDYQFRVYAENSAGLSSPS-DPSKFTLAVSPVDPPGTPDYIDVTRETIT 21500
Query: 829 VRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETAN-SVTLSDLQPGVQYNITIYA- 882
++W+ P + I GY I E N + + T++ L PG +Y I A
Sbjct: 21501 LKWNPPLRDGGSKIVGYSIEKRQGNE-RWVRCNFTDVSECQYTVTGLSPGDRYEFRIIAR 21559
Query: 883 -----VEENQESTPVVIQQETTGTPRSDTVPSPRD---LQFVEVTDVKVTIMWTPPESAV 934
+ +S+ +++ ++ P + P D ++ E +K + P V
Sbjct: 21560 NAVGTISPPSQSSGIIMTRDENVPPIVEFGPEYFDGLIIKSGESLRIKALVQGRPVPR-V 21618
Query: 935 TGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFK--------VFAVSHGRES 986
T ++ V I + E+T + + + + V+ V S
Sbjct: 21619 TWFKDGV-------------EIEKRMNMEITDVLGSTSLFVRDATRDHRGVYTVEAKNAS 21665
Query: 987 KPLTAQQTTKL-DAPTN----LQFVNETDSTVLVRWTPPR----AQITGYRLTVGLTRRG 1037
A+ K+ D P ++F N T + + W P A IT Y + T R
Sbjct: 21666 GSAKAEIKVKVQDTPGKVVGPIRFTNITGEKMTLWWDAPLNDGCAPITHYIIEKRETSRL 21725
Query: 1038 QPRQYNVGPSVSKYPLRNLQPASEYTVSLVAI------KGNQESPKATGVFTTLQPGSSI 1091
Y L +EY + A+ + P + T+ I
Sbjct: 21726 AWALIEDKCEAQSYTAIKLINGNEYQFRVSAVNKFGVGRPLDSDPVVAQIQYTVPDAPGI 21785
Query: 1092 PPYNTEVTETTIVITWTPAPRIG------FKLGVRPSQGGEAPREVTSDSGS---IVVSG 1142
P + +T +I +TW G + L R + + ++ S V+G
Sbjct: 21786 PE-PSNITGNSITLTWARPESDGGSEIQQYILERREKKSTRWVKVISKRPISETRFKVTG 21844
Query: 1143 LTPGVEYVYTIQVLRDGQERDAPIVNKVVT---PLSPPTNLHLEANPDTGVLTVSWERST 1199
LT G EY + + A +++++ P++PP + DT TVS E S
Sbjct: 21845 LTEGNEYEFHVMAENAAGVGPASGISRLIKCREPVNPPGPPTVVKVTDTSKTTVSLEWSK 21904
Query: 1200 TP-----DITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKD-- 1252
+I GY I + + + ++ T +L G EY V +
Sbjct: 21905 PVFDGGMEIIGYIIEMCKADLGDWHKVNAEACV-KTRYTVTDLQAGEEYKFRVSAINGAG 21963
Query: 1253 DKESVPISDTI-------IPEVPQLTDLSFVDITDSSIGLR--------------WTPLN 1291
+S ++ TI PE+ + + + +R W+ +
Sbjct: 21964 KGDSCEVTGTIKAVDRLTAPELDIDANFKQTHVVRAGASIRLFIAYQGRPTPTAVWSKPD 22023
Query: 1292 SSTIIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTT 1351
S+ + I + + + E+ + G YT+T + +G +S T
Sbjct: 22024 SNLSLRADIHTTDSFSTLTV-ENCNRNDAGKYTLT------------VENNSGSKSITFT 22070
Query: 1352 LTQQTAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAE---LSIS 1408
+ PP + F ++ + + W P +D + Y K E +S
Sbjct: 22071 VKVLDTPGPPGPITFKDVTRGSATLMW-DAPLLDGGARIHHYVVEKREASRRSWQVISEK 22129
Query: 1409 PSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDS----PTGIDFSDITANS 1464
+ + +L G Y VS+V E P + P +D D + +S
Sbjct: 22130 CTRQIFKVNDLAEGVPYYFRVSAVNEYGVGEPYEMPEPIVATEQPAPPRRLDVVDTSKSS 22189
Query: 1465 FTVHWIAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRN-SITLTNLTPGTEYVVSI 1519
+ W+ P + ITGY + + G H++ + T+ L TEY +
Sbjct: 22190 AVLAWLKPDHDGGSRITGYLLEMRQK---GSDFWVEAGHTKQLTFTVERLVEKTEYEFRV 22246
Query: 1520 VALNGREESPLLIGQQSTVSDVPR-----DLEVV--------AATPTSL---LISWDAPA 1563
A N S S + P+ DL + A +P ++ + AP
Sbjct: 22247 KAKNDAGYSEPREAFSSVIIKEPQIEPTADLTGITNQLITCKAGSPFTIDVPISGRPAPK 22306
Query: 1564 VTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVD--YTITVYAVTGRGDSPAS 1621
VT + + ET S T ++T T+ G Y +T+ ++ A
Sbjct: 22307 VTWKLEEMRLKETDRVS----ITTTKDRTTLTVKDSMRGDSGRYFLTL-------ENTAG 22355
Query: 1622 SKPISINYRTEIDKPSQM----QVTDVQDNSISVKWLP----SSSPVTGYRVTTTPKNGP 1673
K S+ I +P + +V+ V S + W + +T Y + ++G
Sbjct: 22356 VKTFSVTV-VVIGRPGPVTGPIEVSSVSAESCVLSWGEPKDGGGTEITNY-IVEKRESGT 22413
Query: 1674 GPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAV------TNIDRPK 1727
+ + +T++ + L +EY V ++N G S+PL + P
Sbjct: 22414 TAWQLVNSSVKRTQIKVTHLTKYMEYSFRVSSENRFGVSKPLESAPIIAEHPFVPPSAPT 22473
Query: 1728 GLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGE----EDTAELQGL 1783
V +++ I WE P + Y + + + + + E ++ GL
Sbjct: 22474 RPEVYHVSANAMSIRWEEPYHDGGSKIIGYWVEKKERNTILWVKENKVPCLECNYKVTGL 22533
Query: 1784 RPGSEYTVSVVALH------DDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPP- 1836
G EY AL+ S+P++ + AP + T VT +++S W+ P
Sbjct: 22534 VEGLEYQFRTYALNAAGVSKASEASRPIMA--QNPVDAPGRPEVTDVTRSTVSLIWSAPA 22591
Query: 1837 ---NVQLTGYRVRVTPKEKTGP---MKEINLAPDSSSVVVSGLMVATKYEVSVYALKDT- 1889
++ GY + P + G +K + V+ L YE V A
Sbjct: 22592 YDGGSKVVGYIIERKPVSEVGDGRWLKCNYTIVSDNFFTVTALSEGDTYEFRVLAKNAAG 22651
Query: 1890 LTSRPAQ--GVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVP------ 1941
+ S+ ++ G VT + +PP+ DA ++ R ++ + V P
Sbjct: 22652 VISKGSESTGPVTCRDEYAPPKAE--LDARLHGDLVTIRAGSDLVLDAAVGGKPEPKIIW 22709
Query: 1942 ANGQTPIQRTIKPDV-----RSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDA 1996
G + K + R+ + +D Y T+ NA + V +D+
Sbjct: 22710 TKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSGKYTLTVK-NASGTKAVSVMVKVLDS 22768
Query: 1997 P---SNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREVVPRPRPGVTEA 2049
P L T ++W P+ A IT YI++ + +V P ++
Sbjct: 22769 PGPCGKLTVSRVTQEKCTLAWSLPQEDGGAEITHYIVERRETSRLNWVIVEGECPTLS-Y 22827
Query: 2050 TITGLEPGTEYTIYVIALKN-----NQKSEPLIGRKKTDELPQLVTLPHPNLHGPEILDV 2104
+T L EY V A+ +SEP++ R T+P P P I +
Sbjct: 22828 VVTRLIKNNEYIFRVRAVNKYGPGVPVESEPIVARNS-------FTIPSP----PGIPEE 22876
Query: 2105 PSTVQKTPFV--THPGYDTGNGI 2125
T ++ + T P D GN I
Sbjct: 22877 VGTGKEHIIIQWTKPESDGGNEI 22899
Score = 55.5 bits (132), Expect = 7e-07
Identities = 128/535 (23%), Positives = 202/535 (37%), Gaps = 90/535 (16%)
Query: 593 GIGEWHCQPLQTYPSSSGPVEVFITETPSQP-------NSHPIQWNAPQ---PSHISKYI 642
GIGE PL + P ++ + + P +P NS + W P+ S ++ Y
Sbjct: 9926 GIGE----PLDSEPETARNL-FSVPGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPVTGYW 9980
Query: 643 LRWRPKNSVGRWK-------EATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRF 695
L + S RWK +A G SY + GL G Y+ ++ +I G +
Sbjct: 9981 LEMKDTTSK-RWKRVNRDPIKAMTLGV--SYKVTGLIEGSDYQFRVYAINAAGVGPASL- 10036
Query: 696 DFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWV----SASDTVSGFR 751
S P T+ P +P VT+ T SS + W V+G+
Sbjct: 10037 ------PSDPATARD------PIAPPGPPFPKVTDWTKSSADLEWSPPLKDGGSKVTGYI 10084
Query: 752 VEYELSEEGDEP--QYLDLPSTATSVNIPDLLPGRKY-----IVNVYQISEDGEQSLILS 804
VEY+ EEG E + D T + + L G Y VN+ I E GE + ++
Sbjct: 10085 VEYK--EEGKEEWEKGKDKEVRGTKLVVTGLKEGAFYKFRVRAVNIAGIGEPGEVTDVIE 10142
Query: 805 TSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETA-- 862
PD +D IVV I P+V + E LP+ A
Sbjct: 10143 MKDRLVS---PDLQLDASVRDRIVVHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEATI 10199
Query: 863 ------NSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFV 916
+S+ + + Q Q ++ A E E +I VP P F+
Sbjct: 10200 ETTAISSSMVIKNCQRSHQGVYSLLAKNEAGERKKTIIVDVLD-------VPGPVGTPFL 10252
Query: 917 --EVTDVKVTIMWTPPE----SAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPG 970
+T+ + W PE S +T Y ++ + ++R A V GL G
Sbjct: 10253 AHNLTNESCKLTWFSPEDDGGSPITNYVIEKRESDRRAWTPVTYTVTRQN-ATVQGLIQG 10311
Query: 971 VTYYFKVFA---VSHG---RESKPLTAQQT-TKLDAPTNLQFVNETDSTVLVRWTPPR-- 1021
Y+F++ A + G S+ L ++ T + P +L+ T +TV + W PP+
Sbjct: 10312 KAYFFRIAAENSIGMGPFVETSEALVIREPITVPERPEDLEVKEVTKNTVTLTWNPPKYD 10371
Query: 1022 --AQITGYRLTVGLTRRGQPRQYNVGPSVS-KYPLRNLQPAS--EYTVSLVAIKG 1071
++I Y L L + + +S KY ++ L+ EY VS V I G
Sbjct: 10372 GGSEIINYVLESRLIGTEKFHKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVG 10426
Score = 52.8 bits (125), Expect = 4e-06
Identities = 80/336 (23%), Positives = 120/336 (35%), Gaps = 46/336 (13%)
Query: 602 LQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQP---SHISKYILRWRPKN-SVGRWKEA 657
++ Y S P + +T+ ++ S + W+AP S I+ Y++ R + W+E
Sbjct: 9120 VEVYDRPSPPRNLAVTDIKAE--SCYLTWDAPLDNGGSEITHYVIDKRDASRKKAEWEEV 9177
Query: 658 TIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTP 717
T Y I L P YE ++ ++ +YG + + D V + P
Sbjct: 9178 TNTAVEKRYGIWKLIPNGQYEFRVRAVNKYGISDECKSD-------KVVIQDPYRLPGPP 9230
Query: 718 FSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTA----- 772
P V T S +VSW D Y L + + Y S A
Sbjct: 9231 GKPKVLAR------TKGSMLVSWTPPLDNGGSPITGYWLEKREEGSPYWSRVSRAPITKV 9284
Query: 773 ----TSVNIPDLLPGRKY-----IVNVYQISEDGEQSLILSTSQTTAPDAPPD-PTVDQV 822
N+P LL G KY +N I E S P PP P V
Sbjct: 9285 GLKGVEFNVPRLLEGVKYQFRAMAINAAGIGPPSEPSDPEVAGDPIFPPGPPSCPEVKDK 9344
Query: 823 DDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPE---TANSVTLSDLQPGVQ 875
+SI + W P +PI GY + +N P+ T + +L+ +
Sbjct: 9345 TKSSISLGWKPPAKDGGSPIKGYIVEMQEEGTTDWKRVNEPDKLITTCECVVPNLKELRK 9404
Query: 876 YNITIYAVEENQESTPVVIQQETTG-TPRSDTVPSP 910
Y + AV E ES P +TTG P +D P
Sbjct: 9405 YRFRVKAVNEAGESEP----SDTTGEIPATDIQEEP 9436
Score = 50.4 bits (119), Expect = 2e-05
Identities = 182/937 (19%), Positives = 327/937 (34%), Gaps = 131/937 (13%)
Query: 1277 DITDSSIGLRWTPLNS---STIIGYRITV-VAAGEGIPIFEDFVDSSVGYYTVTGLEPGI 1332
DIT+++ + WT S S I GY + G+ + + + + + VTGL G
Sbjct: 11342 DITENAATVSWTLPKSDGGSPITGYYMERREVTGKWVRVNKTPIADLK--FRVTGLYEGN 11399
Query: 1333 DYDISVITLINGGESAPTTLTQQTAV-------PPPTDLRFTNIGPDTMRVTWAPPPSID 1385
Y+ V G S P+ + PP + + + +T + W P S D
Sbjct: 11400 TYEFRVFAENLAGLSKPSPSSDPIKACRPIKPPGPPINPKLKDKSRETADLVWTKPLS-D 11458
Query: 1386 LTNFLVRYSPVKNEEDVAELSISPSDN-----AVVLTNLLPGTEYVVSVSSVYEQHESTP 1440
+ ++ Y + A+ + D A + L+ G EY + + E P
Sbjct: 11459 GGSPILGYVVECQKPGTAQWNRINKDELIRQCAFRVPGLIEGNEYRFRIKAANIVGEGEP 11518
Query: 1441 LRGRQKT---GLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRV 1497
+ + P ++ D+T + I R++ PE +E +V
Sbjct: 11519 RELAESVIAKDILHPPEVEL-DVTCRDVITVRVGQTIRILA-RVKGRPEPDITWTKEGKV 11576
Query: 1498 PHSRNSITLTNLTPGTE-------------YVVSIVALNGREESPLLIGQQSTVSDVP-- 1542
+ L P E Y++S +G + ++ V D P
Sbjct: 11577 LVREKRVDLIQDLPRVELQIKEAVRADHGKYIISAKNSSGHAQGSAIVN----VLDRPGP 11632
Query: 1543 -RDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISG--- 1598
++L+V T + ISW+ P + G + + + E+ P K + ++
Sbjct: 11633 CQNLKVTNVTKENCTISWENP--------LDNGGSEITNFIVEYRKPNQKGWSIVASDVT 11684
Query: 1599 -------LKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQ---MQVTDVQDNS 1648
L +Y V A G P I ID+P + + + D
Sbjct: 11685 KRLIKANLLANNEYYFRVCAENKVGVGPTIETKTPILAINPIDRPGEPENLHIADKGKTF 11744
Query: 1649 ISVKW----LPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVY 1704
+ +KW SP Y V K + +T ++ Y V
Sbjct: 11745 VYLKWRRPDYDGGSPNLSYHVERRLKGSDDWERVHKGSIKETHYMVDRCVENQIYEFRVQ 11804
Query: 1705 AQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSI-------KIAWESPQGQVSRYRVTY 1757
+N GES V+T + D+ + + I E+ V +
Sbjct: 11805 TKNEGGESD-WVKTEEVVVKEDLQKPVLDLKLSGVLTVKAGDTIRLEAGVRGKPFPEVAW 11863
Query: 1758 SSPEDGIHELFPAP----DGEEDTAELQGLRP----GSEYTVSVVALHDDMESQPLIGTQ 1809
+ +D +L +P D D+++ + G +Y V+ + +
Sbjct: 11864 TKDKDAT-DLTRSPRVKIDTRADSSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATVNVL 11922
Query: 1810 STAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVV 1869
P +LK V+ + W PP G ++ EK K + + S++V+
Sbjct: 11923 DKPGPV-RNLKIVDVSSDRCTVCWDPPEDD-GGCEIQNYILEKC-ETKRMVWSTYSATVL 11979
Query: 1870 VSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENV---------SPPRRARVTDATETT 1920
G V E + Y + ++ G T + V P VT ++
Sbjct: 11980 TPGTTVTRLIEGNEYIFRVRAENKIGTGPPTESKPVIAKTKYDKPGRPDPPEVTKVSKEE 12039
Query: 1921 ITISWRTKT----ETITGFQVDAVPANGQ--TPIQRTIKPDVRSYTITGLQPGTDYKIYL 1974
+T+ W ++ITG+ ++ + P+ ++ P+ R + L P +Y+ +
Sbjct: 12040 MTVVWNPPEYDGGKSITGYFLEKKEKHSTRWVPVNKSAIPE-RRMKVQNLLPDHEYQFRV 12098
Query: 1975 YTLND------NARSSPVVI-DASTAIDAPSNLRFLATTPNSLLVSWQPP----RARITG 2023
N+ + S PVV D P+N R + TT +S+ + W P A I G
Sbjct: 12099 KAENEIGIGEPSLPSRPVVAKDPIEPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAPIIG 12158
Query: 2024 YIIKYEK--PGSPPREVVPRPRPGV----TEATITGLEPGTEYTIYVIALKNNQKSEPLI 2077
Y+++ + P E R E T+T L+ EY V A NQ +
Sbjct: 12159 YVVEMRPKIADASPDEGWKRCNAAAQLVRKEFTVTSLDENQEYEFRVCA--QNQ-----V 12211
Query: 2078 GRKKTDELPQLVTLPHPNLHGPEILDVPSTVQKTPFV 2114
G + EL + + P L PEI D+ ++++K V
Sbjct: 12212 GIGRPAELKEAIK-PKEILEPPEI-DLDASMRKLVIV 12246
Score = 48.5 bits (114), Expect = 8e-05
Identities = 107/537 (19%), Positives = 187/537 (34%), Gaps = 65/537 (12%)
Query: 610 GPVEVFITETPSQPNSHPIQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSY 666
GPV ++ + H + W P+ S ++ YI+ R + W T S+
Sbjct: 12328 GPVSDLKVSDVTKTSCH-VSWAPPENDGGSQVTHYIVEKREADRK-TWSTVTPEVKKTSF 12385
Query: 667 TIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSE 726
+ L PG Y ++ ++ +YG T PV ++ E P L
Sbjct: 12386 HVTNLVPGNEYYFRVTAVNEYG-------PGVPTDVPKPVLASDPLSEPDPPRKL----- 12433
Query: 727 SVTEITASSFVVSWV----SASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLP 782
VTE+T +S ++W+ + G+ Y E+ + S+ + L
Sbjct: 12434 EVTEMTKNSATLAWLPPLRDGGAKIDGYITSYREEEQPADRWTEYSVVKDLSLVVTGLKE 12493
Query: 783 GRKY-----IVNVYQISEDGEQSLILSTSQTTAPD---APPDPTVDQVDDTSIVVRWSRP 834
G+KY N +S E + + P P T+ I
Sbjct: 12494 GKKYKFRVAARNAVGVSLPREAEGVYEAKEQLLPPKILMPEQITIKAGKKLRIEAHVYGK 12553
Query: 835 QAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDL--QPGVQYNITIYAVEENQESTPV 892
P ++ V S ++ ++++ + + D+ + Y++T
Sbjct: 12554 PHPTCKWKKGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIK 12613
Query: 893 VIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPG 948
V+ + G P+ P D+ ++ ++ W P S +T Y V+ V+ G
Sbjct: 12614 VVVMDAPGPPQ-----PPFDISDIDAD--ACSLSWHIPLEDGGSNITNYIVEKCDVS-RG 12665
Query: 949 EHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKL------DAPTN 1002
+ L T V L PG Y F+V A + S+PLT+ + P N
Sbjct: 12666 DWVTALASVTKTSCRVGKLIPGQEYIFRVRAENRFGISEPLTSPKMVAQFPFGVPSEPKN 12725
Query: 1003 LQFVNETDSTVLVRWTPPRAQ----ITGYRLTVGLTRRGQPRQYNVGPSV---SKYPLRN 1055
+ + V W P + I GY + R ++ ++YP
Sbjct: 12726 ARVTKVNKDCIFVAWDRPDSDGGSPIIGY--LIERKERNSLLWVKANDTLVRSTEYPCAG 12783
Query: 1056 LQPASEYTVSLVAIKGNQESP--KATGVFTTLQPGSSIPPYNTE---VTETTIVITW 1107
L EY+ + A+ SP K T T P PP E VT++T+ + W
Sbjct: 12784 LVEGLEYSFRIYALNKAGSSPPSKPTEYVTARMPVD--PPGKPEVIDVTKSTVSLIW 12838
Score = 47.4 bits (111), Expect = 2e-04
Identities = 68/293 (23%), Positives = 108/293 (36%), Gaps = 33/293 (11%)
Query: 730 EITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQY----LDLPSTATSVNIPDLLPGRK 785
+I S VSW +D + Y L E + P+ +D TS+ + L +
Sbjct: 23867 DIQVRSVRVSWRPPADDGGADILGYIL-ERREVPKAAWYTIDSRVRGTSLVVKGLKENVE 23925
Query: 786 YIVNVYQISEDGEQSLILSTSQTTA-----PDAPPD--PTVDQVDDTSIVVRWSRPQ--- 835
Y V ++ G + S T P PP P V V +S+ + WSRP+
Sbjct: 23926 YHFRVSAENQFGISKPLKSEEPVTPKTPLNPPEPPSNPPEVLDVTKSSVSLSWSRPKDDG 23985
Query: 836 -APITGYRIVYSPSVEGSSTELNLPE-TANSVTLSDLQPGVQYNITIYAV------EENQ 887
+ +TGY I + N + T T++ L P +Y I A E +
Sbjct: 23986 GSRVTGYYIERKETSTDKWVRHNKTQITTTMYTVTGLVPDAEYQFRIIAQNDVGLSETSP 24045
Query: 888 ESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIP 943
S PVV + D P +L+ + ++ VT+ W PE + GY V+
Sbjct: 24046 ASEPVVCKDPF------DKPSQPGELEILSISKDSVTLQWEKPECDGGKEILGYWVEYRQ 24099
Query: 944 VNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTK 996
++ + GL Y F+VFA + S+P + K
Sbjct: 24100 SGDSAWKKSNKERIKDKQFTIGGLLEATEYEFRVFAENETGLSRPRRTAMSIK 24152
Score = 43.9 bits (102), Expect = 0.002
Identities = 50/204 (24%), Positives = 83/204 (40%), Gaps = 22/204 (10%)
Query: 717 PFSPLVATSESVTEITASSFVVSWVSASDT----VSGFRVEYELSEEGDEPQYLDLPSTA 772
P P+V + + +S V+SW +D ++ + VE ++EG E Q + +
Sbjct: 24354 PTGPIV-----IEALLKNSAVISWKPPADDGGSWITNYVVEKCEAKEGAEWQLVSSAISV 24408
Query: 773 TSVNIPDLLPGRKYIV-----NVYQISEDGE-QSLILSTSQTTAPDAPPDPTVDQVDDTS 826
T+ I +L Y N + IS+ E S+++ S P AP PT+ V S
Sbjct: 24409 TTCRIVNLTENAGYYFRVSAQNTFGISDPLEVSSVVIIKSPFEKPGAPGKPTITAVTKDS 24468
Query: 827 IVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSV-TLSDLQPGVQYNITIY 881
VV W P A I Y + + + E +V ++ +L G++Y +
Sbjct: 24469 CVVAWKPPASDGGAKIRNYYLEKREKKQNKWISVTTEEIRETVFSVKNLIEGLEYEFRVK 24528
Query: 882 AVEENQESTPVVIQQETTGTPRSD 905
ES I + TP+SD
Sbjct: 24529 CENLGGESEWSEISEPI--TPKSD 24550
Score = 41.2 bits (95), Expect = 0.013
Identities = 92/413 (22%), Positives = 157/413 (38%), Gaps = 51/413 (12%)
Query: 1376 VTWAPPPSID---LTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSV 1432
++W PP +TN++V K + +S + S + NL Y VS+
Sbjct: 24370 ISWKPPADDGGSWITNYVVEKCEAKEGAEWQLVSSAISVTTCRIVNLTENAGYYFRVSAQ 24429
Query: 1433 YEQHESTPLRGRQKTGLDSPTGID-------FSDITANSFTVHWIAPRATITGYRIRHHP 1485
S PL + SP + +T +S V W P A+ G +IR++
Sbjct: 24430 NTFGISDPLEVSSVVIIKSPFEKPGAPGKPTITAVTKDSCVVAW-KPPASDGGAKIRNYY 24488
Query: 1486 EHFSGRPREDRVPHSRNSITLT-----NLTPGTEYVVSIVA--LNGREESPLLIGQQSTV 1538
+ + + + I T NL G EY + L G E + +
Sbjct: 24489 LEKREKKQNKWISVTTEEIRETVFSVKNLIEGLEYEFRVKCENLGGESEWSEISEPITPK 24548
Query: 1539 SDVP----------RDLEVVAATPTSLLISWDA-PAVTVRYYRITYGET----GGNSPVQ 1583
SDVP R+L V + +L+ P V++YR G+ G +Q
Sbjct: 24549 SDVPIQAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYR--QGKEIIADGLKYRIQ 24606
Query: 1584 EFTVPGSKSTATISGLKPGVDYTITVYAV--TGRGDSPASSKPISINYRTEIDKPSQMQ- 1640
EF G I+ + D TVY V T +G S + + + + +I P ++
Sbjct: 24607 EFK--GGYHQLIIASV---TDDDATVYQVRATNQGGSVSGTASLEVEVPAKIHLPKTLEG 24661
Query: 1641 ---VTDVQDNSISVKWLPSSS---PVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQ 1694
V ++ +S+K +P S PV ++ + G + + + G++
Sbjct: 24662 MGAVHALRGEVVSIK-IPFSGKPDPVITWQKGQDLIDNNGHYQVIVTRSFTSLVFPNGVE 24720
Query: 1695 PTVEYVVSVYAQNPSGESQPLVQTAVTNI-DRPKGLAFTDVDVDSIKIAWESP 1746
V A+N G Q V+ V ++ D P+G+ +DV DS+ + W P
Sbjct: 24721 RKDAGFYVVCAKNRFGIDQKTVELDVADVPDPPRGVKVSDVSRDSVNLTWTEP 24773
Score = 37.7 bits (86), Expect = 0.14
Identities = 36/131 (27%), Positives = 53/131 (40%), Gaps = 8/131 (6%)
Query: 894 IQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPVNLPGE 949
I Q+T +D PR ++ +V+ V + WT P S +T Y V+ E
Sbjct: 24737 IDQKTVELDVADVPDPPRGVKVSDVSRDSVNLTWTEPASDGGSKITNYIVEKCATT--AE 24794
Query: 950 HGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQ--TTKLDAPTNLQFVN 1007
R+ +R T V L +Y F+V A + SKP + TK D + +
Sbjct: 24795 RWLRVGQARETRYTVINLFGKTSYQFRVIAENKFGLSKPSEPSEPTITKEDKTRAMNYDE 24854
Query: 1008 ETDSTVLVRWT 1018
E D T V T
Sbjct: 24855 EVDETREVSMT 24865
Score = 35.0 bits (79), Expect = 0.92
Identities = 38/169 (22%), Positives = 71/169 (42%), Gaps = 17/169 (10%)
Query: 1610 YAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWL-PSS---SPVTGYRV 1665
Y V + K + ++ D P ++V+DV +S+++ W P+S S +T Y V
Sbjct: 24727 YVVCAKNRFGIDQKTVELDVADVPDPPRGVKVSDVSRDSVNLTWTEPASDGGSKITNYIV 24786
Query: 1666 TTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPL--VQTAVTNI 1723
+ A +T T+ L Y V A+N G S+P + +T
Sbjct: 24787 EKCATTAERWLRVGQA--RETRYTVINLFGKTSYQFRVIAENKFGLSKPSEPSEPTITKE 24844
Query: 1724 DRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPD 1772
D+ + + + D +VD + +VS + ++SS ++ + A D
Sbjct: 24845 DKTRAMNY-DEEVDETR--------EVSMTKASHSSTKELYEKYMIAED 24884
>gi|110349715 titin isoform N2-B [Homo sapiens]
Length = 26926
Score = 175 bits (443), Expect = 6e-43
Identities = 375/1615 (23%), Positives = 611/1615 (37%), Gaps = 226/1615 (13%)
Query: 630 WNAPQPSHISK---YILRWRPKNSVG--RWKEA--TIPGHLNSYTIKGLKPGVVYEGQLI 682
W+AP SK YI+ +P + VG RW + TI N +T+ L G YE +++
Sbjct: 22462 WSAPAYDGGSKVVGYIIERKPVSEVGDGRWLKCNYTIVSD-NFFTVTALSEGDTYEFRVL 22520
Query: 683 SIQQYGHQEVTRFDFTTTSTST-PVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWV 741
+ G + S ST PVT + VT S V+
Sbjct: 22521 AKNAAGV-------ISKGSESTGPVTCRDEYAPPKAELDARLHGDLVTIRAGSDLVL--- 22570
Query: 742 SASDTVSGFRVEYELS-EEGDEP---------QYLDLPSTATSVNIPDLLPGRKYIVNVY 791
D G + E ++ +GD+ QY +TA + D KY + V
Sbjct: 22571 ---DAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAV-IKFCDRSDSGKYTLTVK 22626
Query: 792 QISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ----APITGYRIVYSP 847
S G +++ + +P TV +V + WS PQ A IT Y +
Sbjct: 22627 NAS--GTKAVSVMVKVLDSPGPCGKLTVSRVTQEKCTLAWSLPQEDGGAEITHYIVERRE 22684
Query: 848 S-------VEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG 900
+ VEG L S ++ L +Y + AV + PV + E
Sbjct: 22685 TSRLNWVIVEGECPTL-------SYVVTRLIKNNEYIFRVRAVNKYGPGVPV--ESEPIV 22735
Query: 901 TPRSDTVPSPRDL-QFVEVTDVKVTIMWTPPES----AVTGYRVDVIPV-NLPGEHGQRL 954
S T+PSP + + V + I WT PES ++ Y VD +L +
Sbjct: 22736 ARNSFTIPSPPGIPEEVGTGKEHIIIQWTKPESDGGNEISNYLVDKREKKSLRWTRVNKD 22795
Query: 955 PISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNL-------QFVN 1007
+ +T +VT L G Y F+V AV+ S+P A P+ + V+
Sbjct: 22796 YVVYDTRLKVTSLMEGCDYQFRVTAVNAAGNSEPSEASNFISCREPSYTPGPPSAPRVVD 22855
Query: 1008 ETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSV--SKYPLRNLQPASE 1061
T ++ + WT P I GY L + Q + + ++ +++ + +L+ +
Sbjct: 22856 TTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDTDQWYRVHTNATIRNTEFTVPDLKMGQK 22915
Query: 1062 YT--VSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGV 1119
Y+ V+ V +KG E ++ ++P I + E+ + + T R G L +
Sbjct: 22916 YSFRVAAVNVKGMSEYSES---IAEIEPVERIEIPDLELADD---LKKTVTIRAGASLRL 22969
Query: 1120 RPSQGGEAPREVT-----SDSGSIVVSGLTPGVEYV------------YTIQVLRDGQER 1162
S G P +T D S + T + YTI+ ++
Sbjct: 22970 MVSVSGRPPPVITWSKQGIDLASRAIIDTTESYSLLIVDKVNRYDAGKYTIEAENQSGKK 23029
Query: 1163 DAPIVNKVV-TPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSL 1221
A ++ KV TP P+ E + D+ +T++WE P I G P N
Sbjct: 23030 SATVLVKVYDTPGPCPSVKVKEVSRDS--VTITWE---IPTIDG----GAPVNNYIVEKR 23080
Query: 1222 EEVVHA-----DQSSCTFDNLSPGLEYNVSVYTVKDDK-----ESVPISDTI-IPEVPQL 1270
E + A + S T +S +E + + V + E SD + + EVP +
Sbjct: 23081 EAAMRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYGIGEPCETSDAVLVSEVPLV 23140
Query: 1271 -TDLSFVDITDSSIGLRW-TPL--NSSTIIGYRITVVAAGEGIPIFEDFVDSSVGYYTVT 1326
L VD+T S++ L W PL S + GY + AG + + +V +TVT
Sbjct: 23141 PAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGTERWMKVVTLKPTVLEHTVT 23200
Query: 1327 GLEPGIDYDISVITLINGGESAP----TTLT-QQTAVPPPTDLRFTNIGPDTMRV----- 1376
L G Y + G S P T +T Q V P DL + + T+ V
Sbjct: 23201 SLNEGEQYLFRIRAQNEKGVSEPRETVTAVTVQDLRVLPTIDL--STMPQKTIHVPAGRP 23258
Query: 1377 -------TWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSV 1429
PPP+ F ++E E + + T + EY + +
Sbjct: 23259 VELVIPIAGRPPPAASW--FFAGSKLRESERVTVETHTKVAKLTIRETTIRDTGEYTLEL 23316
Query: 1430 SSVY-EQHESTPLRGRQKTGLDSPTG-IDFSDITANSFTVHWIAPR----ATITGYRIRH 1483
+V E+ + K G PTG I +I A S T+ W P A ++GY +
Sbjct: 23317 KNVTGTTSETIKVIILDKPG--PPTGPIKIDEIDATSITISWEPPELDGGAPLSGYVVEQ 23374
Query: 1484 HPEHFSG-RPREDRVPHSRNSITLTNLTPGTEYVVSIVALN----GREESPLLIGQQST- 1537
H G P + V +R++ T LT G EYV + A N G +I +S+
Sbjct: 23375 RDAHRPGWLPVSESV--TRSTFKFTRLTEGNEYVFRVAATNRFGIGSYLQSEVIECRSSI 23432
Query: 1538 -VSDVPRDLEVVAATPTSLLISWDAP----AVTVRYYRITYGETGGNSPVQEFTVPGSKS 1592
+ P L++ + + ++W P V Y + E + V+ VP + +
Sbjct: 23433 RIPGPPETLQIFDVSRDGMTLTWYPPEDDGGSQVTGYIVERKEVRADRWVRVNKVPVTMT 23492
Query: 1593 TATISGLKPGVDYTITVYAVTGRGDSPAS--SKPI-SINYRTEIDKPSQMQVTDVQDNSI 1649
+GL G++Y V A+ RG S SKPI +++ KP +VTD S+
Sbjct: 23493 RYRSTGLTEGLEYEHRVTAINARGSGKPSRPSKPIVAMDPIAPPGKPQNPRVTDTTRTSV 23552
Query: 1650 SVKWL----PSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYA 1705
S+ W S VTGY + + TK T E T+ L EY V A
Sbjct: 23553 SLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTKCNTTPTKIREYTLTHLPQGAEYRFRVLA 23612
Query: 1706 QNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDS-IKIAWESPQGQVSRYRVTYSSPEDGI 1764
N G +P + + L + D ++D + QG V R + I
Sbjct: 23613 CNAGGPGEPAEVPGTVKV--TEMLEYPDYELDERYQEGIFVRQGGVIRLTIPIKGKPFPI 23670
Query: 1765 HELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMES------------QPLIGTQSTA 1812
+ +G +D ++ + +T V+ D +S + + +
Sbjct: 23671 CKW--TKEG-QDISKRAMIATSETHTELVIKEADRGDSGTYDLVLENKCGKKAVYIKVRV 23727
Query: 1813 IPAPTD----LKFTQVTPTSLSAQWTPP----NVQLTGYRV--RVTPKEKTGPMKEINLA 1862
I +P L++ + S+ W PP + GY + R PK I+
Sbjct: 23728 IGSPNSPEGPLEYDDIQVRSVRVSWRPPADDGGADILGYILERREVPK---AAWYTIDSR 23784
Query: 1863 PDSSSVVVSGLMVATKYEVSVYALKDTLTSRP--AQGVVTTLENVSPP----RRARVTDA 1916
+S+VV GL +Y V A S+P ++ VT ++PP V D
Sbjct: 23785 VRGTSLVVKGLKENVEYHFRVSAENQFGISKPLKSEEPVTPKTPLNPPEPPSNPPEVLDV 23844
Query: 1917 TETTITISW-RTKTE---TITGFQVDAVPANGQTPIQRT-IKPDVRSYTITGLQPGTDYK 1971
T++++++SW R K + +TG+ ++ + ++ + YT+TGL P +Y+
Sbjct: 23845 TKSSVSLSWSRPKDDGGSRVTGYYIERKETSTDKWVRHNKTQITTTMYTVTGLVPDAEYQ 23904
Query: 1972 IYLYTLND------NARSSPVVI-DASTAIDAPSNLRFLATTPNSLLVSWQPPRA----R 2020
+ ND + S PVV D P L L+ + +S+ + W+ P
Sbjct: 23905 FRIIAQNDVGLSETSPASEPVVCKDPFDKPSQPGELEILSISKDSVTLQWEKPECDGGKE 23964
Query: 2021 ITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEP 2075
I GY ++Y + G + + R + TI GL TEY V A S P
Sbjct: 23965 ILGYWVEYRQSGDSAWKKSNKERIKDKQFTIGGLLEATEYEFRVFAENETGLSRP 24019
Score = 147 bits (371), Expect = 1e-34
Identities = 366/1672 (21%), Positives = 605/1672 (36%), Gaps = 240/1672 (14%)
Query: 612 VEVFITETPSQPNSHPIQ----------WNAPQP---SHISKYILRWRPKNSVGRWKEAT 658
VEV + + P P + I WN P+ S I+ Y++ R +S W + +
Sbjct: 7279 VEVNVLDKPGPPAAFDITDVTNESCLLTWNPPRDDGGSKITNYVVERRATDSEV-WHKLS 7337
Query: 659 IPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPF 718
++ L P Y ++ + YG E PV ++ +T +
Sbjct: 7338 STVKDTNFKATKLIPNKEYIFRVAAENMYGVGE-------------PVQASPITAKYQFD 7384
Query: 719 SPLVATSESVTEITASSFVVSWVSASDT----VSGFRVEYELSEEGDEPQYLDLPSTATS 774
P T ++IT + ++W D ++G+ VE + + +P T+
Sbjct: 7385 PPGPPTRLEPSDITKDAVTLTWCEPDDDGGSPITGYWVERLDPDTDKWVRCNKMPVKDTT 7444
Query: 775 VNIPDLLPGRKYIVNVY--QISEDGEQSL----ILSTSQTTAPDAPPDPTVDQVDDTSIV 828
+ L +KY V ++ G+ S IL P P PTV V TS+
Sbjct: 7445 YRVKGLTNKKKYRFRVLAENLAGPGKPSKSTEPILIKDPIDPPWPPGKPTVKDVGKTSVR 7504
Query: 829 VRWSRPQ----APITGY--RIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYA 882
+ W++P+ A I Y ++ + + E +P T + L L G +Y+ + A
Sbjct: 7505 LNWTKPEHDGGAKIESYVIEMLKTGTDEWVRVAEGVPTTQH--LLPGLMEGQEYSFRVRA 7562
Query: 883 VEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYR 938
V + ES P + PR L+ + +T + WT PE S +T Y
Sbjct: 7563 VNKAGESEPSEPSDPVLCREKLYPPSPPRWLEVINITKNTADLKWTVPEKDGGSPITNYI 7622
Query: 939 VDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSH-GR------ESKPLTA 991
V+ V G + ++T VT L+ G Y F+V A + G+ E L
Sbjct: 7623 VEKRDVRRKGWQTVDTTV-KDTKCTVTPLTEGSLYVFRVAAENAIGQSDYTEIEDSVLAK 7681
Query: 992 QQTTKLDAPTNLQFVNETDSTVLVRWTPPR--AQITGYRLTVGLTRRGQPRQYNVGPSVS 1049
T P L V+ T V ++W PP+ R + R R G +
Sbjct: 7682 DTFTTPGPPYALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKERLGTRWVKAGKTAG 7741
Query: 1050 KYPLRNLQPASEYTVSLVAIKGNQES-----PKATGVFTTLQPGS-SIPPYNTEVTET-- 1101
+ E T ++ E+ + T + + P S PP + VT+
Sbjct: 7742 PDCNFRVTDVIEGTEVQFQVRAENEAGVGHPSEPTEILSIEDPTSPPSPPLDLHVTDAGR 7801
Query: 1102 -TIVITWTP------APRIGFKLGVRPSQGGEAPREVTS----DSGSIVVSGLTPGVEYV 1150
I I W P +P IG+ + + P G E V S D V G+ P EYV
Sbjct: 7802 KHIAIAWKPPEKNGGSPIIGYHVEMCP-VGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYV 7860
Query: 1151 YTIQVLRD-GQERDAPIVNKVVT--PLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYR 1207
++ + G + I VV P PT + LE + ++ + E+ + P +R
Sbjct: 7861 LRVRAVNAIGVSEPSEISENVVAKDPDCKPT-IDLETH---DIIVIEGEKLSIP--VPFR 7914
Query: 1208 ITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEY------NVSVYTV----KDDKESV 1257
PT + +EV +D+ + D++S LE + +YT+ K +
Sbjct: 7915 AVPVPTVSWHKDG-KEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATA 7973
Query: 1258 PISDTIIPEVPQLTDLSFVDITDSSIGLRWTPL---NSSTIIGYRITVVAAGEG--IPIF 1312
I+ +I D+ DIT SS L W P + I+ Y + AG IP+
Sbjct: 7974 SINVKVIGLPGPCKDIKASDITKSSCKLTWEPPEFDGGTPILHYVLERREAGRRTYIPVM 8033
Query: 1313 EDFVDSSVGYYTVTGLEPGIDY--DISVITLINGGESAP---TTLTQQTAVP--PPTDLR 1365
S +TV L P +Y + + + GGE + Q P PP D+
Sbjct: 8034 SGENKLS---WTVKDLIPNGEYFFRVKAVNKVGGGEYIELKNPVIAQDPKQPPDPPVDVE 8090
Query: 1366 FTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLT----NLLP 1421
N + M +TW PP D + ++ Y K + +LT L
Sbjct: 8091 VHNPTAEAMTITW-KPPLYDGGSKIMGYIIEKIAKGEERWKRCNEHLVPILTYTAKGLEE 8149
Query: 1422 GTEYVVSVSSVYEQHESTPLRGRQKT----GLDSP---------------TGIDFSDITA 1462
G EY V + S P R T +D+P +D S +
Sbjct: 8150 GKEYQFRVRAENAAGISEPSRATPPTKAVDPIDAPKVILRTSLEVKRGDEIALDASISGS 8209
Query: 1463 NSFTVHWIAPRATITGYRIRHHPEHFSGRPR------EDRVPHSRNSITLTNLTPGTE-- 1514
T+ WI I I+ R + E V +++ N G
Sbjct: 8210 PYPTITWIKDENVIVPEEIKKRAAPLVRRRKGEVQEEEPFVLPLTQRLSIDNSKKGESQL 8269
Query: 1515 ------------YVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAP 1562
Y++ + +G ++P + T P + TS+L W+ P
Sbjct: 8270 RVRDSLRPDHGLYMIKVENDHGIAKAPCTVSVLDTPGP-PINFVFEDIRKTSVLCKWEPP 8328
Query: 1563 -----AVTVRYYRITYGETGGNSPVQEFTVPGS---KSTATISGLKPGVDYTITVYAVTG 1614
+ + Y T + P E+ V S +++ L G +Y V A
Sbjct: 8329 LDDGGSEIINY---TLEKKDKTKPDSEWIVVTSTLRHCKYSVTKLIEGKEYLFRVRAENR 8385
Query: 1615 RGDS-PASSKP-ISINYRTEIDKPSQMQVTDVQDNSISVKW---LPSSSPVTGYRVTTTP 1669
G P SKP ++ + D P + V DV NS+ VKW + SP+ GY +
Sbjct: 8386 FGPGPPCVSKPLVAKDPFGPPDAPDKPIVEDVTSNSMLVKWNEPKDNGSPILGYWLEKRE 8445
Query: 1670 KNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSG------ESQPLVQTAVTNI 1723
N ++ + + + ++GL + YV V A+N +G S P +
Sbjct: 8446 VNSTHWSRVNKSLLNALKANVDGLLEGLTYVFRVCAENAAGPGKFSPPSDPKTAHDPISP 8505
Query: 1724 DRPKGLAFTDVDVDSIKIAWESPQ----GQVSRYRVTYSSPEDGIHELFPAPDGEEDTAE 1779
P TD +I++ WE P G++ Y V G +E + +
Sbjct: 8506 PGPPIPRVTDTSSTTIELEWEPPAFNGGGEIVGYFV--DKQLVGTNEWSRCTEKMIKVRQ 8563
Query: 1780 --LQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPN 1837
++ +R G++Y + V A++ E P TQ + P + ++ +
Sbjct: 8564 YTVKEIREGADYKLRVSAVNAAGEGPP-GETQPVTVAEPQEPPAVELDVS------VKGG 8616
Query: 1838 VQLTGYRVRVTPKEKTG---PMKEINLAP---DSSSVVVSGLMVATKYEVSVYALKDTLT 1891
+Q+ + P TG P K D VV+ V TK E+ +KD L
Sbjct: 8617 IQIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKDRVVIDN--VGTKSEL---IIKDALR 8671
Query: 1892 SRPAQGVVTTLENVS---PPRRARVTDATETTI------------TISWRTKTE----TI 1932
+ V+T + R V D + ++W + I
Sbjct: 8672 KDHGRYVITATNSCGSKFAAARVEVFDVPGPVLDLKPVVTNRKMCLLNWSDPEDDGGSEI 8731
Query: 1933 TGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDAST 1992
TGF ++ A T ++ I+ + ITGL G +YK + N PV I
Sbjct: 8732 TGFIIERKDAKMHT-WRQPIETERSKCDITGLLEGQEYKFRVIAKNKFGCGPPVEIGPIL 8790
Query: 1993 AID------APSNLRFLATTPNSLLVSWQPPRAR----ITGYIIKYEKPGSPPREVVPRP 2042
A+D +P L + T +++ + W+ PR+ I GYII+ + P E V +
Sbjct: 8791 AVDPLGPPTSPERLTYTERTKSTITLDWKEPRSNGGSPIQGYIIEKRRHDKPDFERVNKR 8850
Query: 2043 RPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRK---KTDELPQLVTL 2091
T + L+ Y V A+ +SEP + + DE+P + L
Sbjct: 8851 LCPTTSFLVENLDEHQMYEFRVKAVNEIGESEPSLPLNVVIQDDEVPPTIKL 8902
Score = 144 bits (362), Expect = 1e-33
Identities = 288/1427 (20%), Positives = 522/1427 (36%), Gaps = 163/1427 (11%)
Query: 696 DFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYE 755
D+T T+ ++ + + P S + ++ + ++SW + Y
Sbjct: 12868 DYTITAENSSGSKSATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYI 12927
Query: 756 LSE-EGDEPQYLDLPSTA--TSVNIPDLLPGRKY-----IVNVYQISEDGEQSLILSTSQ 807
+ + E P + + +T TS ++ L+ G +Y N Y + + ++ +
Sbjct: 12928 VDKRETSRPNWAQVSATVPITSCSVEKLIEGHEYQFRICAENKYGVGDPVFTEPAIAKNP 12987
Query: 808 TTAPDAPPDPTVDQVDDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNL-PETA 862
P P + + + V W P +PITGY + + + T++N P
Sbjct: 12988 YDPPGRCDPPVISNITKDHMTVSWKPPADDGGSPITGYLLEKRETQAVNWTKVNRKPIIE 13047
Query: 863 NSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVK 922
++ + LQ G +Y + A+ + P + P + + T
Sbjct: 13048 RTLKATGLQEGTEYEFRVTAINKAGPGKPSDASKAAYARDPQYPPGPPAFPKVYDTTRSS 13107
Query: 923 VTIMWTPPE----SAVTGYRVDVIPVNLPGEHGQRLPIS-RNTFAEVTGLSPGVTYYFKV 977
V++ W P S + GY V+V + LP + + T EVTGL Y F+V
Sbjct: 13108 VSLSWGKPAYDGGSPIIGYLVEVKRADSDNWVRCNLPQNLQKTRFEVTGLMEDTQYQFRV 13167
Query: 978 FAVSHGRESKP-----------LTAQQTTKLDAPTNLQFVNETDST----VLVRWTPPRA 1022
+AV+ S P + +LDA + T V V+ PP
Sbjct: 13168 YAVNKIGYSDPSDVPDKHYPKDILIPPEGELDADLRKTLILRAGVTMRLYVPVKGRPP-P 13226
Query: 1023 QITGYRLTVGLTRR-GQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGV 1081
+IT + V L R G + + + N A +Y ++L G +E V
Sbjct: 13227 KITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKYILTLENSCGKKEYTIVVKV 13286
Query: 1082 FTTLQPGSSIPPYNTEVTETTIVITWTP------APRIGFKLGVRPSQGGEAPREVTSDS 1135
T PG + E+++ + +TW P +P I + + R ++ T S
Sbjct: 13287 LDT--PGPPVNVTVKEISKDSAYVTWEPPIIDGGSPIINYVVQKRDAERKSWSTVTTECS 13344
Query: 1136 -GSIVVSGLTPGVEYVYTIQVLRD------GQERDAPIVNKVVTPLSPPTNLHLEANPDT 1188
S V+ L G Y + + + G+ RDA V TP P +L + + +
Sbjct: 13345 KTSFRVANLEEGKSYFFRVFAENEYGIGDPGETRDA--VKASQTP-GPVVDLKVRSVSKS 13401
Query: 1189 GVLTVSWERSTTPD---ITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNV 1245
++ W++ + I GY + + N + V+ + + +L+ G EY
Sbjct: 13402 S-CSIGWKKPHSDGGSRIIGYVVDFL----TEENKWQRVMKSLSLQYSAKDLTEGKEYTF 13456
Query: 1246 SVYTVKDDKESVPISDTIIP---------EVPQLTDLSFVDITDSSIGLR---------- 1286
V ++ E P T++ ++ L DL ++ +S+ L+
Sbjct: 13457 RVSAENENGEGTPSEITVVARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPIKGKPAPS 13516
Query: 1287 --WTPLNSSTIIGYRITVVAAGEGIP-IFEDFVDSSVGYYTVTGLEPGIDYDISVITLIN 1343
W R++V ++ I D S G YT+T + ++ +
Sbjct: 13517 VSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKEGTISIKVV 13576
Query: 1344 GGESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAPPP---SIDLTNFLVRYSPVKNEE 1400
G PT ++F + + M + WAPP ++TN+++ N +
Sbjct: 13577 GKPGIPT-----------GPIKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDSVNNK 13625
Query: 1401 DVAELSISPSDNAVVLTNLLPGTEYVVSVSS-----VYEQHESTPLRGRQKTGL-DSPTG 1454
V S + +T L G EY VS+ V E +S P+ R + D+P
Sbjct: 13626 WVTCAS-AVQKTTFRVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVPDAPPP 13684
Query: 1455 IDFSDITANSFTVHWIAPRAT----ITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLT 1510
+ D+ +S ++ W P+ T ITGY + + R ++ P +T LT
Sbjct: 13685 PNIVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTPIRMRDFKVTGLT 13744
Query: 1511 PGTEYVVSIVALN----GREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAV-- 1564
G EY ++A+N G+ P D P EV+ T S+ + W P
Sbjct: 13745 EGLEYEFRVMAINLAGVGKPSLPSEPVVALDPIDPPGKPEVINITRNSVTLIWTEPKYDG 13804
Query: 1565 --TVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASS 1622
+ Y + + S ++ V + T++ L G Y + A G A S
Sbjct: 13805 GHKLTGYIVEKRDLPSKSWMKANHVNVPECAFTVTDLVEGGKYEFRIRAKNTAGAISAPS 13864
Query: 1623 KPI-SINYRTEIDKPSQMQVTDVQD------------NSISV--KWLPSSS-PVTGYRVT 1666
+ +I + E + P+ + ++D N+IS+ K LP SS G +
Sbjct: 13865 ESTETIICKDEYEAPTIVLDPTIKDGLTIKAGDTIVLNAISILGKPLPKSSWSKAGKDIR 13924
Query: 1667 TTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRP 1726
P T+ P + +TI+ ++ A NP G V+ V ++ P
Sbjct: 13925 ------PSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFGTKVEHVKVTVLDVPGP 13978
Query: 1727 KG-LAFTDVDVDSIKIAWESP---QGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQG 1782
G + ++V + + W P G + + + + D +
Sbjct: 13979 PGPVEISNVSAEKATLTWTPPLEDGGSPIKSYILEKRETSRLLWTVVSEDIQSCRHVATK 14038
Query: 1783 LRPGSEYTVSVVALH-----DDMESQPLIGTQSTAIPAPTDL-KFTQVTPTSLSAQWTPP 1836
L G+EY V A++ + ++S+P+ P P + + + VT + + W P
Sbjct: 14039 LIQGNEYIFRVSAVNHYGKGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSWKRP 14098
Query: 1837 ----NVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTS 1892
++TGY V K+ ++ I V+GL + YE V A
Sbjct: 14099 VDDGGSEITGYHVERREKKSLRWVRAIKTPVSDLRCKVTGLQEGSTYEFRVSAENRAGIG 14158
Query: 1893 RPAQGVVTTLEN-----VSPPRRARVTDATETTITISWRTKTE----TITGFQVDAVPAN 1943
P++ + L PP VTD T+ + +++W ITG+ V+
Sbjct: 14159 PPSEASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLAWGKPHYDGGLEITGYVVEHQKVG 14218
Query: 1944 GQTPIQRTIKPDVR--SYTITGLQPGTDYKIYLYTLNDNARSSPVVI 1988
+ I+ T +R + + LQ Y + +ND P VI
Sbjct: 14219 DEAWIKDTTGTALRITQFVVPDLQTKEKYNFRISAINDAGVGEPAVI 14265
Score = 136 bits (342), Expect = 3e-31
Identities = 287/1435 (20%), Positives = 516/1435 (35%), Gaps = 196/1435 (13%)
Query: 794 SEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ----APITGYRIVYSPSV 849
+ G +S + P P ++++ ++ W P + IT Y + +
Sbjct: 12875 NSSGSKSATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYIVDKRETS 12934
Query: 850 EGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPS 909
+ +++ S ++ L G +Y I A + PV + P P
Sbjct: 12935 RPNWAQVSATVPITSCSVEKLIEGHEYQFRICAENKYGVGDPVFTEPAIAKNPYDP--PG 12992
Query: 910 PRDLQFVE-VTDVKVTIMWTPPE----SAVTGYRVDVIPVNLPG-EHGQRLPISRNTFAE 963
D + +T +T+ W PP S +TGY ++ R PI T +
Sbjct: 12993 RCDPPVISNITKDHMTVSWKPPADDGGSPITGYLLEKRETQAVNWTKVNRKPIIERTL-K 13051
Query: 964 VTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKL-------DAPTNLQFVNETDSTVLVR 1016
TGL G Y F+V A++ KP A + P + + T S+V +
Sbjct: 13052 ATGLQEGTEYEFRVTAINKAGPGKPSDASKAAYARDPQYPPGPPAFPKVYDTTRSSVSLS 13111
Query: 1017 WTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSVSK--YPLRNLQPASEYTVSLVAIK 1070
W P + I GY + V + N+ ++ K + + L ++Y + A+
Sbjct: 13112 WGKPAYDGGSPIIGYLVEVKRADSDNWVRCNLPQNLQKTRFEVTGLMEDTQYQFRVYAVN 13171
Query: 1071 GNQESPKATGVFTTLQPGSSIPP---YNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEA 1127
S + IPP + ++ +T I+ R G + + G
Sbjct: 13172 KIGYSDPSDVPDKHYPKDILIPPEGELDADLRKTLIL-------RAGVTMRLYVPVKGRP 13224
Query: 1128 PREVTSDSGSIVVS---GLT------------------PGVEYVYTIQVLRDGQERDAPI 1166
P ++T ++ + GL +Y+ T++ +++ I
Sbjct: 13225 PPKITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKYILTLE--NSCGKKEYTI 13282
Query: 1167 VNKVVTPLSPPTNLHL-EANPDTGVLTVSWERSTTPDITG----YRITTTPTNGQQGNSL 1221
V KV+ PP N+ + E + D+ +T WE P I G + ++ +
Sbjct: 13283 VVKVLDTPGPPVNVTVKEISKDSAYVT--WE---PPIIDGGSPIINYVVQKRDAERKSWS 13337
Query: 1222 EEVVHADQSSCTFDNLSPGLEYNVSVYTVKD--------DKESVPISDTIIPEVPQLTDL 1273
++S NL G Y V+ + +++V S T P V DL
Sbjct: 13338 TVTTECSKTSFRVANLEEGKSYFFRVFAENEYGIGDPGETRDAVKASQTPGPVV----DL 13393
Query: 1274 SFVDITDSSIGLRWTPLNS---STIIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEP 1330
++ SS + W +S S IIGY + + ++ + S Y+ L
Sbjct: 13394 KVRSVSKSSCSIGWKKPHSDGGSRIIGYVVDFLTEENK---WQRVMKSLSLQYSAKDLTE 13450
Query: 1331 GIDYDISVITLINGGESAPTTLT---QQTAVPPPTDLRFTNIGPDT-------------M 1374
G +Y V GE P+ +T + V P DL+ PD +
Sbjct: 13451 GKEYTFRVSAENENGEGTPSEITVVARDDVVAPDLDLKGL---PDLCYLAKENSNFRLKI 13507
Query: 1375 RVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLL-------PGTEYVV 1427
+ P PS+ S K E+ +A + +++ V T L+ +Y +
Sbjct: 13508 PIKGKPAPSV---------SWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTI 13558
Query: 1428 SVSSVYEQHEST-PLRGRQKTGLDSPTG-IDFSDITANSFTVHWIAPR----ATITGYRI 1481
++ +V E T ++ K G+ PTG I F ++TA + T+ W P+ + IT Y I
Sbjct: 13559 TLKNVAGTKEGTISIKVVGKPGI--PTGPIKFDEVTAEAMTLKWAPPKDDGGSEITNY-I 13615
Query: 1482 RHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN------GREESPLLIGQQ 1535
+ + + + + +T L G EY + A N G + P++
Sbjct: 13616 LEKRDSVNNKWVTCASAVQKTTFRVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHP 13675
Query: 1536 STVSDVPRDLEVVAATPTSLLISWDAPAVT----VRYYRITYGETGGNSPVQEFTVPGSK 1591
V D P +V S+ ++W P T + Y + + E + P
Sbjct: 13676 FDVPDAPPPPNIVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTPIRM 13735
Query: 1592 STATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISV 1651
++GL G++Y V A+ G S + ID P + +V ++ NS+++
Sbjct: 13736 RDFKVTGLTEGLEYEFRVMAINLAGVGKPSLPSEPVVALDPIDPPGKPEVINITRNSVTL 13795
Query: 1652 KWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQN 1707
W +TGY V K + T+ L +Y + A+N
Sbjct: 13796 IWTEPKYDGGHKLTGYIVEKRDLPSKSWMKANHVNVPECAFTVTDLVEGGKYEFRIRAKN 13855
Query: 1708 PSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQV----------------S 1751
+G ++ T I + + A T V +IK G S
Sbjct: 13856 TAGAISAPSESTETIICKDEYEAPTIVLDPTIKDGLTIKAGDTIVLNAISILGKPLPKSS 13915
Query: 1752 RYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQST 1811
+ I ++ P T + + EYT++ +
Sbjct: 13916 WSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFGTKVEHVKVTVLDV 13975
Query: 1812 AIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVR--VTPKEKTGPMKEINLAPDSSSV- 1868
P P ++ + V+ + WTPP ++ G ++ + K +T + ++ D S
Sbjct: 13976 PGP-PGPVEISNVSAEKATLTWTPP-LEDGGSPIKSYILEKRETSRLLWTVVSEDIQSCR 14033
Query: 1869 -VVSGLMVATKYEVSVYALKDTLTSRPAQG----VVTTLENVSPPRRARVTDATETTITI 1923
V + L+ +Y V A+ P Q +V PP + V++ T+ T T+
Sbjct: 14034 HVATKLIQGNEYIFRVSAVNHYGKGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTATV 14093
Query: 1924 SWRTKTE----TITGFQVDAVPANGQTPIQRTIKPDVRSY--TITGLQPGTDYKIYLYTL 1977
SW+ + ITG+ V+ + R IK V +TGLQ G+ Y+ +
Sbjct: 14094 SWKRPVDDGGSEITGYHVERREKKSLRWV-RAIKTPVSDLRCKVTGLQEGSTYEFRVSAE 14152
Query: 1978 N-------DNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYII 2026
N A S ++ DA+ PSN TT S ++W P ITGY++
Sbjct: 14153 NRAGIGPPSEASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLAWGKPHYDGGLEITGYVV 14212
Query: 2027 KYEKPGSPPREVVPRPRPG----VTEATITGLEPGTEYTIYVIALKNNQKSEPLI 2077
+++K G E + G +T+ + L+ +Y + A+ + EP +
Sbjct: 14213 EHQKVGD---EAWIKDTTGTALRITQFVVPDLQTKEKYNFRISAINDAGVGEPAV 14264
Score = 134 bits (338), Expect = 9e-31
Identities = 378/1880 (20%), Positives = 675/1880 (35%), Gaps = 278/1880 (14%)
Query: 628 IQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISI 684
+ W P S I+ Y+L R +V K P + GL+ G YE ++ +I
Sbjct: 13009 VSWKPPADDGGSPITGYLLEKRETQAVNWTKVNRKPIIERTLKATGLQEGTEYEFRVTAI 13068
Query: 685 QQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSW---- 740
+ G + + S + P V + T SS +SW
Sbjct: 13069 NKAGPGKPSD------------ASKAAYARDPQYPPGPPAFPKVYDTTRSSVSLSWGKPA 13116
Query: 741 VSASDTVSGFRVEYELSEEGDEPQYLDLPST--ATSVNIPDLLPGRKYIVNVYQISEDGE 798
+ G+ VE + + + D +LP T + L+ +Y VY +++ G
Sbjct: 13117 YDGGSPIIGYLVEVKRA-DSDNWVRCNLPQNLQKTRFEVTGLMEDTQYQFRVYAVNKIG- 13174
Query: 799 QSLILSTSQTTAPD--------APPDPTVDQVDDTSIVVR---WSRPQAPITGYRIVYSP 847
+ + PD PP+ +D ++++R R P+ G P
Sbjct: 13175 -----YSDPSDVPDKHYPKDILIPPEGELDADLRKTLILRAGVTMRLYVPVKGRP---PP 13226
Query: 848 SVEGSSTELNLPETAN-SVTLSDLQPGV-----------QYNITIYAVEENQESTPVVIQ 895
+ S +NL + + +D + +Y +T+ +E T VV
Sbjct: 13227 KITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKYILTLENSCGKKEYTIVVKV 13286
Query: 896 QETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPGEHG 951
+T G P + TV E++ + W PP S + Y V
Sbjct: 13287 LDTPGPPVNVTVK--------EISKDSAYVTWEPPIIDGGSPIINYVVQKRDAERKSWST 13338
Query: 952 QRLPISRNTFAEVTGLSPGVTYYFKVFAVSH---GRESKPLTAQQTTKLDAP-TNLQFVN 1007
S+ +F V L G +Y+F+VFA + G + A + ++ P +L+ +
Sbjct: 13339 VTTECSKTSF-RVANLEEGKSYFFRVFAENEYGIGDPGETRDAVKASQTPGPVVDLKVRS 13397
Query: 1008 ETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYT 1063
+ S+ + W P ++I GY + LT + ++ S+ +Y ++L EYT
Sbjct: 13398 VSKSSCSIGWKKPHSDGGSRIIGYVVDF-LTEENKWQRVMKSLSL-QYSAKDLTEGKEYT 13455
Query: 1064 VSLVAIKGNQE-SPKATGVFT---TLQPG---SSIPPYNTEVTETT-----IVITWTPAP 1111
+ A N E +P V + P +P E + I I PAP
Sbjct: 13456 FRVSAENENGEGTPSEITVVARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPIKGKPAP 13515
Query: 1112 RIGFKLGVRP-SQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKV 1170
+ +K G P + E ++ + +++V YTI + ++ I KV
Sbjct: 13516 SVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKEGTISIKV 13575
Query: 1171 VTPLSPPTNLHLEANPDTGVLTVSW---ERSTTPDITGYRITTTPTNGQQGNSLEEVVHA 1227
V PT +T+ W + +IT Y + + + + V
Sbjct: 13576 VGKPGIPTGPIKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDSVNNKWVTCASAV-- 13633
Query: 1228 DQSSCTFDNLSPGLEYNVSV-----YTVKDDKESVPI---SDTIIPEVPQLTDLSFVDIT 1279
+++ L G+EY V Y V + +S PI +P+ P ++ VD+
Sbjct: 13634 QKTTFRVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVPDAPPPPNI--VDVR 13691
Query: 1280 DSSIGLRWT---PLNSSTIIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDI 1336
S+ L WT S I GY + + + + + VTGL G++Y+
Sbjct: 13692 HDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTPIRMRDFKVTGLTEGLEYEF 13751
Query: 1337 SVITLINGGESAPTTLTQQTA----VPPPTDLRFTNIGPDTMRVTWAPPP---SIDLTNF 1389
V+ + G P+ ++ + PP NI +++ + W P LT +
Sbjct: 13752 RVMAINLAGVGKPSLPSEPVVALDPIDPPGKPEVINITRNSVTLIWTEPKYDGGHKLTGY 13811
Query: 1390 LVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEY---------VVSVSSVYEQHESTP 1440
+V + ++ + ++ + A +T+L+ G +Y ++S+ E E+
Sbjct: 13812 IVEKRDLPSKSWMKANHVNVPECAFTVTDLVEGGKYEFRIRAKNTAGAISAPSESTETII 13871
Query: 1441 LRGRQK--TGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVP 1498
+ + T + PT D I A V +I G + P+ + +D P
Sbjct: 13872 CKDEYEAPTIVLDPTIKDGLTIKAGDTIV---LNAISILGKPL---PKSSWSKAGKDIRP 13925
Query: 1499 HSRNSITLTNLT-----------PGTEYVVSIVALNGREESPLLIGQQSTVSDV---PRD 1544
IT T + EY ++ G + + + TV DV P
Sbjct: 13926 SDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFGTKVEHVKV----TVLDVPGPPGP 13981
Query: 1545 LEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATI-------- 1596
+E+ + ++W P E GG SP++ + + +++ +
Sbjct: 13982 VEISNVSAEKATLTWTPPL-----------EDGG-SPIKSYILEKRETSRLLWTVVSEDI 14029
Query: 1597 -------SGLKPGVDYTITVYAVT--GRGDSPASSKPISINYR-TEIDKPSQMQVTDVQD 1646
+ L G +Y V AV G+G+ P S+P+ + R P + +V++V
Sbjct: 14030 QSCRHVATKLIQGNEYIFRVSAVNHYGKGE-PVQSEPVKMVDRFGPPGPPEKPEVSNVTK 14088
Query: 1647 NSISVKWL----PSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVS 1702
N+ +V W S +TGY V K + + GLQ Y
Sbjct: 14089 NTATVSWKRPVDDGGSEITGYHVERREKKSLRWVRAIKTPVSDLRCKVTGLQEGSTYEFR 14148
Query: 1703 VYAQNPSGESQP-------LVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQG----QVS 1751
V A+N +G P L++ A P TD S +AW P +++
Sbjct: 14149 VSAENRAGIGPPSEASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLAWGKPHYDGGLEIT 14208
Query: 1752 RYRVTYSSPEDGIHELFPAPDGEEDTA-ELQGLRPGSEYTVSVVALHDDMESQPLIGTQS 1810
Y V + D T + L+ +Y + A++D +P +
Sbjct: 14209 GYVVEHQKVGDEAWIKDTTGTALRITQFVVPDLQTKEKYNFRISAINDAGVGEPAV---- 14264
Query: 1811 TAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPD------ 1864
IP ++ L A+ V G +R+ K P E+ D
Sbjct: 14265 --IPDVEIVEREMAPDFELDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKN 14322
Query: 1865 ------SSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVT--TLENVSPPRRARVTDA 1916
+ S + + +Y+ + + + G V L+ P R TD
Sbjct: 14323 RANIENTESFTLLIIPECNRYDTGKFVMTIENPAGKKSGFVNVRVLDTPGPVLNLRPTDI 14382
Query: 1917 TETTITISWRTKT----ETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKI 1972
T+ ++T+ W IT + V+ A ++ T K +Y +TGL G +Y
Sbjct: 14383 TKDSVTLHWDLPLIDGGSRITNYIVEKREATRKSYSTATTKCHKCTYKVTGLSEGCEYFF 14442
Query: 1973 YLYTLNDNARSSPV----VIDASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGY 2024
+ N+ P + AS A P +L + T +++ ++W P+ ++ITGY
Sbjct: 14443 RVMAENEYGIGEPTETTEPVKASEAPSPPDSLNIMDITKSTVSLAWPKPKHDGGSKITGY 14502
Query: 2025 IIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDE 2084
+I+ ++ GS + + E + L G EYT V+A+ + +S P R
Sbjct: 14503 VIEAQRKGSDQWTHITTVKG--LECVVRNLTEGEEYTFQVMAVNSAGRSAPRESRPVI-- 14558
Query: 2085 LPQLVTLPHPNLHGPEILDVPSTVQKTPFVTHPGYDTGNGIQLPGTSGQQPSV----GQQ 2140
+ + LP +L G + + + G + +++P +P+V G Q
Sbjct: 14559 VKEQTMLPELDLRG---------IYQKLVIAKAGDNI--KVEIPVLGRPKPTVTWKKGDQ 14607
Query: 2141 MIFEEHGFRRTTPPTTATP--------IRHRPRPYPPN----VGEEIQIGHIPREDVDYH 2188
++ + +R TTAT +R PYP VGE + I D+
Sbjct: 14608 ILKQT---QRVNFETTATSTILNINECVRSDSGPYPLTARNIVGEVGDVITIQVHDIP-- 14662
Query: 2189 LYPHGPGLNPNASTGQEALSQTTISWAPFQDTSEYIISCHPV---GTDEEP-LQFRVPGT 2244
GP P + + T SW P ++ IS + V TD ++
Sbjct: 14663 ----GPPTGP-IKFDEVSSDFVTFSWDPPENDGGVPISNYVVEMRQTDSTTWVELATTVI 14717
Query: 2245 STSATLTGLTRGATYNIIVEALKDQQRHKVREEVVTVGNSVNEGLNQPTDDSCFDPYTVS 2304
T+ T LT G Y V+A Q R+ V + + N P V+
Sbjct: 14718 RTTYKATRLTTGLEYQFRVKA---QNRYGVGPGITSACIVANYPFKVPGPPGTPQVTAVT 14774
Query: 2305 HYAVGDEW-ERMSESGFKLL 2323
++ W E +S+ G +L
Sbjct: 14775 KDSMTISWHEPLSDGGSPIL 14794
Score = 128 bits (322), Expect = 6e-29
Identities = 343/1604 (21%), Positives = 574/1604 (35%), Gaps = 260/1604 (16%)
Query: 611 PVEVFITETPSQPNSHPIQWNAPQ---PSHISKYILRWRPKNSVGRWKEATIPGHLNS-- 665
P ++ I + S +S + W+ P S ++ Y++ R + W + G + +
Sbjct: 20673 PAKIRIAD--STKSSITLGWSKPVYDGGSAVTGYVVEIR-QGEEEEWTTVSTKGEVRTTE 20729
Query: 666 YTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATS 725
Y + LKPGV Y ++ ++ G E + + S +
Sbjct: 20730 YVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQAKDILEAPEIDLDVALRTSVIAKAG 20789
Query: 726 ESVTEITASSF----VVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLL 781
E V + V+W + G Y + E D L +P +
Sbjct: 20790 EDVQVLIPFKGRPPPTVTWRKDEKNL-GSDARYSI-ENTDSSSLLTIPQVTRNDT----- 20842
Query: 782 PGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ----AP 837
KYI+ + + + S + S P A V V ++ + W P +P
Sbjct: 20843 --GKYILTIENGVGEPKSSTV-SVKVLDTPAACQKLQVKHVSRGTVTLLWDPPLIDGGSP 20899
Query: 838 ITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQE 897
I Y I + + + + ++ ++ S L DL + + A E P E
Sbjct: 20900 IINYVIEKRDATKRTWSVVSHKCSSTSFKLIDLSEKTPFFFRVLAENEIGIGEPC----E 20955
Query: 898 TTGTPRSDTVPSP-RDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPVNLPGEHG- 951
TT ++ VP+P RDL + T V + WT P+ S +T Y V+ GE
Sbjct: 20956 TTEPVKAAEVPAPIRDLSMKDSTKTSVILSWTKPDFDGGSVITEY---VVERKGKGEQTW 21012
Query: 952 QRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDS 1011
IS+ EV+ L F+VFA + S P+T T + L E D
Sbjct: 21013 SHAGISKTCEIEVSQLKEQSVLEFRVFAKNEKGLSDPVTIGPITVKE----LIITPEVDL 21068
Query: 1012 TVLVRWTPPRAQIT---GYRLTVGLTRRGQPRQYNVGPSVS----KYPLRNLQ------P 1058
+ + P AQ+T G+ + + L +G+P+ PS+S PL+ +
Sbjct: 21069 SDI-----PGAQVTVRIGHNVHLELPYKGKPK-----PSISWLKDGLPLKESEFVRFSKT 21118
Query: 1059 ASEYTVSLVAIKGNQESPKATGVFT-------------TLQPGSSI--PPYNTEVTETTI 1103
++ T+S+ K + K T + TL P S P E+ ++
Sbjct: 21119 ENKITLSIKNAK-KEHGGKYTVILDNAVCRIAVPITVITLGPPSKPKGPIRFDEIKADSV 21177
Query: 1104 VITWTPAPRIGFKLGVRPSQGGEAP------REVTSDSGSIVVSG----------LTPGV 1147
+++W G GGE RE + + +V S L
Sbjct: 21178 ILSWDVPEDNG---------GGEITCYSIEKRETSQTNWKMVCSSVARTTFKVPNLVKDA 21228
Query: 1148 EYVYTIQVLRDGQERDAPIVNKVVTP-----LSPPTNLHLEANPDTGVLTVSWERSTTP- 1201
EY + ++ + P+V+ ++ + P + N + ++++W+
Sbjct: 21229 EYQFRVRA-ENRYGVSQPLVSSIIVAKHQFRIPGPPGKPVIYNVTSDGMSLTWDAPVYDG 21287
Query: 1202 --DITGYRITTTPTNG---QQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKES 1256
++TG+ + N Q+ N+ + + T L GL+Y VY S
Sbjct: 21288 GSEVTGFHVEKKERNSILWQKVNT--SPISGREYRAT--GLVEGLDYQFRVYAENSAGLS 21343
Query: 1257 VPISDT-----IIPEVPQLTDLSFVDITDSSIGLRWTPL---NSSTIIGYRITVVAAGEG 1308
P + + P P T ++D+T +I L+W P S I+GY I E
Sbjct: 21344 SPSDPSKFTLAVSPVDPPGTP-DYIDVTRETITLKWNPPLRDGGSKIVGYSIEKRQGNER 21402
Query: 1309 IPIFEDFVDSSVGYYTVTGLEPGIDYDISVI------TLINGGESAPTTLTQQTAVPPPT 1362
+ +F D S YTVTGL PG Y+ +I T+ +S+ +T+ VPP
Sbjct: 21403 W-VRCNFTDVSECQYTVTGLSPGDRYEFRIIARNAVGTISPPSQSSGIIMTRDENVPP-- 21459
Query: 1363 DLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNE---EDVAELSISPSDNAVVLTNL 1419
GP+ LV+ PV +D E+ + + +T++
Sbjct: 21460 ---IVEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMN---MEITDV 21513
Query: 1420 LPGTEYVV--------SVSSVYEQHESTPLRGRQKTGLDSPTG-----IDFSDITANSFT 1466
L T V V +V ++ S + K + G I F++IT T
Sbjct: 21514 LGSTSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQDTPGKVVGPIRFTNITGEKMT 21573
Query: 1467 VHWIAPR----ATITGYRI-RHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVA 1521
+ W AP A IT Y I + + ED+ S T L G EY + A
Sbjct: 21574 LWWDAPLNDGCAPITHYIIEKRETSRLAWALIEDKC--EAQSYTAIKLINGNEYQFRVSA 21631
Query: 1522 LN----GR--EESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGE 1575
+N GR + P++ Q TV D P E T S+ ++W P E
Sbjct: 21632 VNKFGVGRPLDSDPVVAQIQYTVPDAPGIPEPSNITGNSITLTWARP------------E 21679
Query: 1576 TGGNSPVQEFTV-----------------PGSKSTATISGLKPGVDYTITVYAVTGRGDS 1618
+ G S +Q++ + P S++ ++GL G +Y V A G
Sbjct: 21680 SDGGSEIQQYILERREKKSTRWVKVISKRPISETRFKVTGLTEGNEYEFHVMAENAAGVG 21739
Query: 1619 PASSKPISINYRTEIDKPSQ---MQVTDVQDNSISVKW----LPSSSPVTGYRVTTTPKN 1671
PAS I R ++ P ++VTD ++S++W + GY + +
Sbjct: 21740 PASGISRLIKCREPVNPPGPPTVVKVTDTSKTTVSLEWSKPVFDGGMEIIGYIIEMCKAD 21799
Query: 1672 GPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTA-VTNIDRPKGLA 1730
K +T T+ LQ EY V A N +G+ T + +DR L
Sbjct: 21800 LGDWHKVNAEACVKTRYTVTDLQAGEEYKFRVSAINGAGKGDSCEVTGTIKAVDR---LT 21856
Query: 1731 FTDVDVDS-IKIAWESPQGQVSRYRVTY----------SSPEDGIH---ELFPAPDGEED 1776
++D+D+ K G R + Y S P+ + ++
Sbjct: 21857 APELDIDANFKQTHVVRAGASIRLFIAYQGRPTPTAVWSKPDSNLSLRADIHTTDSFSTL 21916
Query: 1777 TAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPP 1836
T E +YT++V + T P P + F VT S + W P
Sbjct: 21917 TVENCNRNDAGKYTLTVENNSGSKSITFTVKVLDTPGP-PGPITFKDVTRGSATLMWDAP 21975
Query: 1837 NVQLTGYRVRVTPKEKTGPMKE----INLAPDSSSVVVSGLMVATKYEVSVYALKDTLTS 1892
+ G R+ EK + I+ V+ L Y V A+ +
Sbjct: 21976 LLD-GGARIHHYVVEKREASRRSWQVISEKCTRQIFKVNDLAEGVPYYFRVSAVNEYGVG 22034
Query: 1893 RPAQ--GVVTTLENVSPPRRARVTDATETTITISW----RTKTETITGFQVDAVPANGQT 1946
P + + E +PPRR V D ++++ ++W ITG+ ++
Sbjct: 22035 EPYEMPEPIVATEQPAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSDF 22094
Query: 1947 PIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATT 2006
++ + ++T+ L T+Y+ + ND S P +S I P
Sbjct: 22095 WVEAGHTKQL-TFTVERLVEKTEYEFRVKAKNDAGYSEPREAFSSVIIKEPQ------IE 22147
Query: 2007 PNSLLVSWQPPRARITGYIIKYEKPGSPPREVVP---RPRPGVT 2047
P + L IT +I K GSP VP RP P VT
Sbjct: 22148 PTADLTG-------ITNQLITC-KAGSPFTIDVPISGRPAPKVT 22183
Score = 124 bits (311), Expect = 1e-27
Identities = 291/1338 (21%), Positives = 513/1338 (38%), Gaps = 174/1338 (13%)
Query: 780 LLPGRKYI-----VNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRP 834
++ G +YI VN Y I E E +++ + P P P V ++ S+ V WSRP
Sbjct: 20533 IIKGNEYIFRVRAVNKYGIGEPLESDSVVAKNAFVTPGPPGIPEVTKITKNSMTVVWSRP 20592
Query: 835 QA----PITGYRIVYSPSVEGSSTEL---NLPETANSVTLSDLQPGVQYNI-TIYAVEEN 886
A I+GY + ++ + +T VT QY + + A +
Sbjct: 20593 IADGGSDISGYFLEKRDKKSLGWFKVLKETIRDTRQKVTGLTENSDYQYRVCAVNAAGQG 20652
Query: 887 QESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVI 942
S P + D P ++ + T +T+ W+ P SAVTGY V++
Sbjct: 20653 PFSEP---SEFYKAADPIDPPGPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVVEI- 20708
Query: 943 PVNLPGEHGQRLPIS-----RNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTK- 996
GE + +S R T V+ L PGV YYF+V AV+ + +P+ + +
Sbjct: 20709 ---RQGEEEEWTTVSTKGEVRTTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQA 20765
Query: 997 ---LDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQP--------RQYNVG 1045
L+AP E D V +R T A+ G + V + +G+P + N+G
Sbjct: 20766 KDILEAP-------EIDLDVALR-TSVIAK-AGEDVQVLIPFKGRPPPTVTWRKDEKNLG 20816
Query: 1046 PSVSKYPLRNLQPASEYTVS----------LVAIKGNQESPKATGVFTTL--QPGSSIPP 1093
S ++Y + N +S T+ ++ I+ PK++ V + P +
Sbjct: 20817 -SDARYSIENTDSSSLLTIPQVTRNDTGKYILTIENGVGEPKSSTVSVKVLDTPAACQKL 20875
Query: 1094 YNTEVTETTIVITWTP------APRIGFKLGVRPS---QGGEAPREVTSDSGSIV-VSGL 1143
V+ T+ + W P +P I + + R + + +S S ++ +S
Sbjct: 20876 QVKHVSRGTVTLLWDPPLIDGGSPIINYVIEKRDATKRTWSVVSHKCSSTSFKLIDLSEK 20935
Query: 1144 TPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDI 1203
TP V + G+ + K +P +L ++ + T V+ +SW T PD
Sbjct: 20936 TPFFFRVLAENEIGIGEPCETTEPVKAAEVPAPIRDLSMKDSTKTSVI-LSW---TKPDF 20991
Query: 1204 TGYRITTTPTNGQQGNSLEEVVHADQS-SCTFD----NLSPGLEYNVSVYTVKDDKESVP 1258
G + T ++G + HA S +C + LE+ V K + V
Sbjct: 20992 DGGSVITEYVVERKGKGEQTWSHAGISKTCEIEVSQLKEQSVLEFRVFAKNEKGLSDPVT 21051
Query: 1259 ISDTIIPEVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGY----RITVVAAGEGIPIFE- 1313
I + E+ ++ DI + + +R N + Y + ++ +G+P+ E
Sbjct: 21052 IGPITVKELIITPEVDLSDIPGAQVTVR-IGHNVHLELPYKGKPKPSISWLKDGLPLKES 21110
Query: 1314 DFVDSSVGYYTVT------GLEPGIDYDISVITLINGGESAPTTLTQQTAVPPPTDLRFT 1367
+FV S +T E G Y + + + T +T P +RF
Sbjct: 21111 EFVRFSKTENKITLSIKNAKKEHGGKYTVILDNAVCRIAVPITVITLGPPSKPKGPIRFD 21170
Query: 1368 NIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSI---SPSDNAVVLTNLLPGTE 1424
I D++ ++W P + + YS K E + S + + NL+ E
Sbjct: 21171 EIKADSVILSWDVPED-NGGGEITCYSIEKRETSQTNWKMVCSSVARTTFKVPNLVKDAE 21229
Query: 1425 YVVSVSSVYEQHESTPL-----RGRQKTGLDSPTGID-FSDITANSFTVHWIAP----RA 1474
Y V + S PL + + + P G ++T++ ++ W AP +
Sbjct: 21230 YQFRVRAENRYGVSQPLVSSIIVAKHQFRIPGPPGKPVIYNVTSDGMSLTWDAPVYDGGS 21289
Query: 1475 TITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQ 1534
+TG+ + + + + P S T L G +Y + A N S
Sbjct: 21290 EVTGFHVEKKERNSILWQKVNTSPISGREYRATGLVEGLDYQFRVYAENSAGLSSPSDPS 21349
Query: 1535 QSTVS----DVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYG---ETGGNSPVQEFTV 1587
+ T++ D P + + T ++ + W+ P + Y G V+
Sbjct: 21350 KFTLAVSPVDPPGTPDYIDVTRETITLKWNPPLRDGGSKIVGYSIEKRQGNERWVRCNFT 21409
Query: 1588 PGSKSTATISGLKPGVDYTITVYAVTGRGD-SPASSKPISINYRTEIDKPSQMQVTDVQD 1646
S+ T++GL PG Y + A G SP S I R E P + D
Sbjct: 21410 DVSECQYTVTGLSPGDRYEFRIIARNAVGTISPPSQSSGIIMTRDENVPPIVEFGPEYFD 21469
Query: 1647 -------NSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTK----TAGPDQTEMTIEGLQP 1695
S+ +K L PV RVT K+G K T T + +
Sbjct: 21470 GLIIKSGESLRIKALVQGRPVP--RVTWF-KDGVEIEKRMNMEITDVLGSTSLFVRDATR 21526
Query: 1696 TVEYVVSVYAQNPSGESQPLVQTAVTNIDRP----KGLAFTDVDVDSIKIAWESPQGQ-- 1749
V +V A+N SG ++ ++ V D P + FT++ + + + W++P
Sbjct: 21527 DHRGVYTVEAKNASGSAKAEIKVKVQ--DTPGKVVGPIRFTNITGEKMTLWWDAPLNDGC 21584
Query: 1750 --VSRYRVTYSSPEDGIHELFPAPDGEEDTAELQG-----LRPGSEYTVSVVALHD---- 1798
++ Y + L ED E Q L G+EY V A++
Sbjct: 21585 APITHYIIEKRETSRLAWALI------EDKCEAQSYTAIKLINGNEYQFRVSAVNKFGVG 21638
Query: 1799 -DMESQPLIGTQSTAIP-APTDLKFTQVTPTSLSAQWTPP----NVQLTGYRVRVTPKEK 1852
++S P++ +P AP + + +T S++ W P ++ Y + K+
Sbjct: 21639 RPLDSDPVVAQIQYTVPDAPGIPEPSNITGNSITLTWARPESDGGSEIQQYILERREKKS 21698
Query: 1853 TGPMKEINLAPDSSS-VVVSGLMVATKYEVSVYALKDTLTSRPAQGV---VTTLENVS-- 1906
T +K I+ P S + V+GL +YE V A ++ PA G+ + E V+
Sbjct: 21699 TRWVKVISKRPISETRFKVTGLTEGNEYEFHVMA-ENAAGVGPASGISRLIKCREPVNPP 21757
Query: 1907 -PPRRARVTDATETTITISWRTKT----ETITGFQVDAVPANGQTPIQRTIKPDVRS-YT 1960
PP +VTD ++TT+++ W I G+ ++ A+ + + V++ YT
Sbjct: 21758 GPPTVVKVTDTSKTTVSLEWSKPVFDGGMEIIGYIIEMCKADLGDWHKVNAEACVKTRYT 21817
Query: 1961 ITGLQPGTDYKIYLYTLN 1978
+T LQ G +YK + +N
Sbjct: 21818 VTDLQAGEEYKFRVSAIN 21835
Score = 124 bits (310), Expect = 2e-27
Identities = 338/1629 (20%), Positives = 573/1629 (35%), Gaps = 196/1629 (12%)
Query: 624 NSHPIQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNS--YTIKGLKPGVVYE 678
NS + W P+ S I +YIL R K S RW + ++ + + GL G YE
Sbjct: 21669 NSITLTWARPESDGGSEIQQYILERREKKST-RWVKVISKRPISETRFKVTGLTEGNEYE 21727
Query: 679 GQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVV 738
+++ G + PV P P V VT+ + ++ +
Sbjct: 21728 FHVMAENAAGVGPASGIS-RLIKCREPVNP--------PGPPTVV---KVTDTSKTTVSL 21775
Query: 739 SW----VSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQIS 794
W + G+ +E ++ GD + T + DL G +Y V I+
Sbjct: 21776 EWSKPVFDGGMEIIGYIIEMCKADLGDWHKVNAEACVKTRYTVTDLQAGEEYKFRVSAIN 21835
Query: 795 EDGEQSLILSTSQTTAPD--APPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGS 852
G+ T A D P+ +D + VVR Y+ +P+ S
Sbjct: 21836 GAGKGDSCEVTGTIKAVDRLTAPELDIDANFKQTHVVRAGASIRLFIAYQGRPTPTAVWS 21895
Query: 853 STELNLPETANSVTLSDLQPGVQYNIT-------IYAVEENQESTPVVIQQETTGTPRSD 905
+ NL A+ T N VE N S + + TP
Sbjct: 21896 KPDSNLSLRADIHTTDSFSTLTVENCNRNDAGKYTLTVENNSGSKSITFTVKVLDTPGP- 21954
Query: 906 TVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPGEHGQRLPISRNTF 961
P + F +VT T+MW P + + Y V+ + +R F
Sbjct: 21955 ----PGPITFKDVTRGSATLMWDAPLLDGGARIHHYVVEKREASRRSWQVISEKCTRQIF 22010
Query: 962 AEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQ----TTKLDAPTNLQFVNETDSTVLVRW 1017
+V L+ GV YYF+V AV+ +P + T + P L V+ + S+ ++ W
Sbjct: 22011 -KVNDLAEGVPYYFRVSAVNEYGVGEPYEMPEPIVATEQPAPPRRLDVVDTSKSSAVLAW 22069
Query: 1018 TPP----RAQITGYRLTVGLTRRGQPRQYNVGPSVS-KYPLRNLQPASEY---------- 1062
P ++ITGY L + ++G G + + + L +EY
Sbjct: 22070 LKPDHDGGSRITGYLLE--MRQKGSDFWVEAGHTKQLTFTVERLVEKTEYEFRVKAKNDA 22127
Query: 1063 -------TVSLVAIKGNQESPKA--TGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRI 1113
S V IK Q P A TG+ L + P+ +V I+ PAP++
Sbjct: 22128 GYSEPREAFSSVIIKEPQIEPTADLTGITNQLITCKAGSPFTIDVP-----ISGRPAPKV 22182
Query: 1114 GFKL-GVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVT 1172
+KL +R + T D ++ V G Y + + + + V+
Sbjct: 22183 TWKLEEMRLKETDRVSITTTKDRTTLTVKDSMRGDSGRYFLTLENTAGVKTFSVTVVVIG 22242
Query: 1173 PLSPPTNLHLEANPDTGVLTVSW---ERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQ 1229
P T ++ +SW + +IT Y + + + V Q
Sbjct: 22243 RPGPVTGPIEVSSVSAESCVLSWGEPKDGGGTEITNYIVEKRESGTTAWQLVNSSVKRTQ 22302
Query: 1230 SSCTFDNLSPGLEYNVSV-----YTVKDDKESVPI---SDTIIPEVPQLTDLSFVDITDS 1281
T +L+ +EY+ V + V ES PI + P P T ++ +
Sbjct: 22303 IKVT--HLTKYMEYSFRVSSENRFGVSKPLESAPIIAEHPFVPPSAP--TRPEVYHVSAN 22358
Query: 1282 SIGLRWTPL---NSSTIIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISV 1338
++ +RW S IIGY + + + E+ V Y VTGL G++Y
Sbjct: 22359 AMSIRWEEPYHDGGSKIIGYWVEKKERNTILWVKENKVPCLECNYKVTGLVEGLEYQFRT 22418
Query: 1339 ITLINGGES----APTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAPPP---SIDLTNFLV 1391
L G S A + Q V P T++ T+ + W+ P + +++
Sbjct: 22419 YALNAAGVSKASEASRPIMAQNPVDAPGRPEVTDVTRSTVSLIWSAPAYDGGSKVVGYII 22478
Query: 1392 RYSPVKNEEDVAELSIS---PSDNAVVLTNLLPGTEYVVSVSS------VYEQHEST-PL 1441
PV D L + SDN +T L G Y V + + + EST P+
Sbjct: 22479 ERKPVSEVGDGRWLKCNYTIVSDNFFTVTALSEGDTYEFRVLAKNAAGVISKGSESTGPV 22538
Query: 1442 RGRQ-----KTGLDSPTGIDFSDITANSFTVHWIA----PRATITGYRIRHHPEHFSGRP 1492
R K LD+ D I A S V A P I + +
Sbjct: 22539 TCRDEYAPPKAELDARLHGDLVTIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVS 22598
Query: 1493 REDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVP---RDLEVVA 1549
+ + I + + +Y +++ +G + +++ V D P L V
Sbjct: 22599 LQYTGKRATAVIKFCDRSDSGKYTLTVKNASGTKAVSVMV----KVLDSPGPCGKLTVSR 22654
Query: 1550 ATPTSLLISWDAP----AVTVRYYRITYGETGGNSPVQEFTVPGSKSTAT--ISGLKPGV 1603
T ++W P + +Y + ET S + V G T + ++ L
Sbjct: 22655 VTQEKCTLAWSLPQEDGGAEITHYIVERRET---SRLNWVIVEGECPTLSYVVTRLIKNN 22711
Query: 1604 DYTITVYAVTGRGDS-PASSKPI-SINYRTEIDKPSQMQVTDVQDNSISVKWLPSSS--- 1658
+Y V AV G P S+PI + N T P + I ++W S
Sbjct: 22712 EYIFRVRAVNKYGPGVPVESEPIVARNSFTIPSPPGIPEEVGTGKEHIIIQWTKPESDGG 22771
Query: 1659 -PVTGYRVTTTPKNGPGPTK-TKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLV 1716
++ Y V K T+ K T + + L +Y V A N +G S+P
Sbjct: 22772 NEISNYLVDKREKKSLRWTRVNKDYVVYDTRLKVTSLMEGCDYQFRVTAVNAAGNSEPSE 22831
Query: 1717 QTAVTNIDR-------PKGLAFTDVDVDSIKIAWESPQGQVSRYRVTY-----SSPEDGI 1764
+ + P D SI +AW P V Y D
Sbjct: 22832 ASNFISCREPSYTPGPPSAPRVVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDTDQW 22891
Query: 1765 HELFPAPDGEEDTAELQGLRPGSEYTVSVVALH---------DDMESQPLIGTQSTAIPA 1815
+ + + L+ G +Y+ V A++ E +P+ + +
Sbjct: 22892 YRVHTNATIRNTEFTVPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEIPDLEL 22951
Query: 1816 PTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTG---PMKEINLAPDSSSVVVSG 1872
DLK T S + V ++G V K G + I +S S+++
Sbjct: 22952 ADDLKKTVTIRAGASLRLM---VSVSGRPPPVITWSKQGIDLASRAIIDTTESYSLLI-- 23006
Query: 1873 LMVATKYEVSVYALKDTLTS--RPAQGVVTTLENVSPPRRARVTDATETTITISWRTKT- 1929
+ +Y+ Y ++ S + A +V + P +V + + ++TI+W T
Sbjct: 23007 VDKVNRYDAGKYTIEAENQSGKKSATVLVKVYDTPGPCPSVKVKEVSRDSVTITWEIPTI 23066
Query: 1930 ---ETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKI-----YLYTLNDNA 1981
+ + V+ A + T K Y I+GL GT Y +Y + +
Sbjct: 23067 DGGAPVNNYIVEKREAAMRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYGIGEPC 23126
Query: 1982 RSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPP----RARITGYIIKYEKPGSPPRE 2037
+S V+ + + P+ L + T +++ ++W+ P +R+TGY+++ K G+
Sbjct: 23127 ETSDAVLVSEVPL-VPAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGTERWM 23185
Query: 2038 VVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEP-----LIGRKKTDELP--QLVT 2090
V +P V E T+T L G +Y + A SEP + + LP L T
Sbjct: 23186 KVVTLKPTVLEHTVTSLNEGEQYLFRIRAQNEKGVSEPRETVTAVTVQDLRVLPTIDLST 23245
Query: 2091 LPHPNLHGP 2099
+P +H P
Sbjct: 23246 MPQKTIHVP 23254
Score = 123 bits (309), Expect = 2e-27
Identities = 310/1432 (21%), Positives = 508/1432 (35%), Gaps = 230/1432 (16%)
Query: 814 PPDPT-VDQVDDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTLS 868
PP P + V + W+ P +PI Y + + T ++ + +
Sbjct: 13978 PPGPVEISNVSAEKATLTWTPPLEDGGSPIKSYILEKRETSRLLWTVVSEDIQSCRHVAT 14037
Query: 869 DLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVE-VTDVKVTIMW 927
L G +Y + AV + PV Q E P P + V VT T+ W
Sbjct: 14038 KLIQGNEYIFRVSAVNHYGKGEPV--QSEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSW 14095
Query: 928 TPPE----SAVTGYRVDVIPV-NLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSH 982
P S +TGY V+ +L + P+S + +VTGL G TY F+V A +
Sbjct: 14096 KRPVDDGGSEITGYHVERREKKSLRWVRAIKTPVS-DLRCKVTGLQEGSTYEFRVSAENR 14154
Query: 983 GRESKPLTAQQTTKL-DA------PTNLQFVNETDSTVLVRWTPPR----AQITGYRLTV 1031
P A + + DA P+N + T + + W P +ITGY +
Sbjct: 14155 AGIGPPSEASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLAWGKPHYDGGLEITGYVVEH 14214
Query: 1032 GLTRRGQPRQYNVGPS--VSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGS 1089
+ G + ++++ + +LQ +Y + AI A +
Sbjct: 14215 QKVGDEAWIKDTTGTALRITQFVVPDLQTKEKYNFRISAINDAGVGEPAVIPDVEIVERE 14274
Query: 1090 SIPPY--NTEVTETTIVITWTPAPRIGFKLGVR-PSQGGEAPREVTSDSGSIVVSG---- 1142
P + + E+ T +V R G + + P +G AP EVT +I +
Sbjct: 14275 MAPDFELDAELRRTLVV-------RAGLSIRIFVPIKGRPAP-EVTWTKDNINLKNRANI 14326
Query: 1143 ---------LTPGVEYVYT---IQVLRDGQERDAPIVN-KVVTPLSPPTNLH-LEANPDT 1188
+ P T + + + + + VN +V+ P NL + D+
Sbjct: 14327 ENTESFTLLIIPECNRYDTGKFVMTIENPAGKKSGFVNVRVLDTPGPVLNLRPTDITKDS 14386
Query: 1189 GVLTVSWERSTTPD---ITGYRITTTPTNGQQGNSLEEVVHADQSSCTFD--NLSPGLEY 1243
+T+ W+ IT Y + + ++ H CT+ LS G EY
Sbjct: 14387 --VTLHWDLPLIDGGSRITNYIVEKREATRKSYSTATTKCH----KCTYKVTGLSEGCEY 14440
Query: 1244 NVSV-----YTVKDDKESV-PISDTIIPEVPQLTDLSFVDITDSSIGLRWTPLN---SST 1294
V Y + + E+ P+ + P P L+ +DIT S++ L W S
Sbjct: 14441 FFRVMAENEYGIGEPTETTEPVKASEAPSPPD--SLNIMDITKSTVSLAWPKPKHDGGSK 14498
Query: 1295 IIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLE-------PGIDYDISVITLINGGES 1347
I GY I G D TV GLE G +Y V+ + + G S
Sbjct: 14499 ITGYVIEAQRKGS---------DQWTHITTVKGLECVVRNLTEGEEYTFQVMAVNSAGRS 14549
Query: 1348 APT----TLTQQTAVPPPTDLR-------FTNIGPDT---MRVTWAPPPSIDLTNFLVRY 1393
AP + ++ + P DLR G + + V P P++
Sbjct: 14550 APRESRPVIVKEQTMLPELDLRGIYQKLVIAKAGDNIKVEIPVLGRPKPTVTW------- 14602
Query: 1394 SPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGL---- 1449
K + + + + + + +L E V S S Y PL R G
Sbjct: 14603 ---KKGDQILKQTQRVNFETTATSTILNINECVRSDSGPY------PLTARNIVGEVGDV 14653
Query: 1450 ---------DSPTG-IDFSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPRED 1495
PTG I F +++++ T W P I+ Y + S E
Sbjct: 14654 ITIQVHDIPGPPTGPIKFDEVSSDFVTFSWDPPENDGGVPISNYVVEMRQTD-STTWVEL 14712
Query: 1496 RVPHSRNSITLTNLTPGTEYVVSIVALN------GREESPLLIGQQSTVSDVPRDLEVVA 1549
R + T LT G EY + A N G + ++ V P +V A
Sbjct: 14713 ATTVIRTTYKATRLTTGLEYQFRVKAQNRYGVGPGITSACIVANYPFKVPGPPGTPQVTA 14772
Query: 1550 ATPTSLLISWDAP----AVTVRYYRITYGETGGN--SPVQEFTVPGSKSTATISGLKPGV 1603
T S+ ISW P + Y + E G V + VPG+ + SGL G+
Sbjct: 14773 VTKDSMTISWHEPLSDGGSPILGYHVERKERNGILWQTVSKALVPGNIFKS--SGLTDGI 14830
Query: 1604 DYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKW----LPSSSP 1659
Y V A G S S + ID P + ++ +++++KW
Sbjct: 14831 AYEFRVIAENMAGKSKPSKPSEPMLALDPIDPPGKPVPLNITRHTVTLKWAKPEYTGGFK 14890
Query: 1660 VTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQ-- 1717
+T Y V K + + E T+ GL Y V A+N +G P +
Sbjct: 14891 ITSYIVEKRDLPNGRWLKANFSNILENEFTVSGLTEDAAYEFRVIAKNAAGAISPPSEPS 14950
Query: 1718 TAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDT 1777
A+T D DV+ IK+ + + + + D P + +D
Sbjct: 14951 DAITCRD--------DVEAPKIKVDVKFKDTVILKAGEAFRLEADVSGRPPPTMEWSKDG 15002
Query: 1778 AELQGL---------------------RPGSEYTVSVVALHDDMESQPLIGTQSTAIPAP 1816
EL+G R YT++ A + ++ + + P P
Sbjct: 15003 KELEGTAKLEIKIADFSTNLVNKDSTRRDSGAYTLT--ATNPGGFAKHIFNVKVLDRPGP 15060
Query: 1817 TD--LKFTQVTPTSLSAQWTPP----NVQLTGYRVRVTPKEKTGPMKEINLAPD--SSSV 1868
+ L T+VT W PP ++ Y + K +T + N+A + + +
Sbjct: 15061 PEGPLAVTEVTSEKCVLSWFPPLDDGGAKIDHY---IVQKRETSRLAWTNVASEVQVTKL 15117
Query: 1869 VVSGLMVATKY-----EVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITI 1923
V+ L+ +Y V+ Y + + L S P V PP+ VT T+ ++ +
Sbjct: 15118 KVTKLLKGNEYIFRVMAVNKYGVGEPLESEPVL-AVNPYGPPDPPKNPEVTTITKDSMVV 15176
Query: 1924 SW----RTKTETITGFQVDAVPANGQTPIQRTIK--PDVRSYTITGLQPGTDYKIYLYTL 1977
W I + V+ GQ I+ K D+R Y ++GL G +Y+ +
Sbjct: 15177 CWGHPDSDGGSEIINYIVERRDKAGQRWIKCNKKTLTDLR-YKVSGLTEGHEYEFRIMAE 15235
Query: 1978 NDNARSSP-------VVIDASTAIDAPSNLRFLATTPNSLLVSWQPP----RARITGYII 2026
N S+P D P N R L T+ +S+ ++W P + ITGY++
Sbjct: 15236 NAAGISAPSPTSPFYKACDTVFKPGPPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMV 15295
Query: 2027 KYEKPGSPPREVVPRPRP-GVTEATITGLEPGTEYTIYVIALKNNQKSEPLI 2077
+ P ++V P T TITGL EY I + A+ + EP +
Sbjct: 15296 EIALPEEDEWQIVTPPAGLKATSYTITGLTENQEYKIRIYAMNSEGLGEPAL 15347
Score = 123 bits (309), Expect = 2e-27
Identities = 338/1634 (20%), Positives = 602/1634 (36%), Gaps = 228/1634 (13%)
Query: 613 EVFITETPSQPNSHP-----------IQWNAPQ---PSHISKYILRWRPKNSVGRWKEAT 658
E ++ P P P +QW P S I+ YI+ R GRW +A+
Sbjct: 17016 ECYVARDPCDPPGTPEPIMVKRNEITLQWTKPVYDGGSMITGYIVEKRDLPD-GRWMKAS 17074
Query: 659 IPGHLNS-YTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTP 717
+ + +T+ GL YE ++I+ G + S ST +T +
Sbjct: 17075 FTNVIETQFTVSGLTEDQRYEFRVIAKNAAGA-------ISKPSDST----GPITAKDEV 17123
Query: 718 FSPLVATSESVTEITASSFVVSWVSASD-------TVSGFRVEYELSEEGD-EPQYLDLP 769
P ++ + + ++ +D T+ R + E+ E E + D
Sbjct: 17124 ELPRISMDPKFRDTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFK 17183
Query: 770 STATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPT-VDQVDDTSIV 828
+ V + G +YI+ ++ G +S ++ P P P V V
Sbjct: 17184 ALLI-VKDAIRIDGGQYILRASNVA--GSKSFPVNVKVLDRPGPPEGPVQVTGVTSEKCS 17240
Query: 829 VRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITI---- 880
+ WS P + I+ Y + + + T + NS+ ++ L G +Y I
Sbjct: 17241 LTWSPPLQDGGSDISHYVVEKRETSRLAWTVVASEVVTNSLKVTKLLEGNEYVFRIMAVN 17300
Query: 881 -YAVEENQESTPVVIQQETTGTPRSDTVPSP-RDLQFVEVTDVKVTIMWTPPES----AV 934
Y V E ES PV+++ +P P + L+ + +T+ W P+S +
Sbjct: 17301 KYGVGEPLESAPVLMKNPFV-------LPGPPKSLEVTNIAKDSMTVCWNRPDSDGGSEI 17353
Query: 935 TGYRV---DVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTA 991
GY V D + + +R+ R VTGL+ Y F+V A + +P A
Sbjct: 17354 IGYIVEKRDRSGIRWIKCNKRRITDLR---LRVTGLTEDHEYEFRVSAENAAGVGEPSPA 17410
Query: 992 -------QQTTKLDAPTNLQFVNETDSTVLVRWTPP----RAQITGYRLTVGLTRRGQPR 1040
K PTN V+ T +++ + W P ++I GY V + + +
Sbjct: 17411 TVYYKACDPVFKPGPPTNAHIVDTTKNSITLAWGKPIYDGGSEILGY--VVEICKADEEE 17468
Query: 1041 QYNVGPS----VSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNT 1096
V P V+++ + L EY + + A+ +AT V T++P +
Sbjct: 17469 WQIVTPQTGLRVTRFEISKLTEHQEYKIRVCALN-KVGLGEATSVPGTVKPEDKLEAPEL 17527
Query: 1097 EVTETT---IVITWTPAPRIGFKLGVRPS-------QGGEAPREVTSDSG----SIVVSG 1142
++ IV+ + RI RP+ + GE +V + G + +
Sbjct: 17528 DLDSELRKGIVVRAGGSARIHIPFKGRPTPEITWSREEGEFTDKVQIEKGVNYTQLSIDN 17587
Query: 1143 LTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHL-EANPDTGVLTVSWERSTTP 1201
Y +++ + A + KV+ PP NL + E D+ L WE P
Sbjct: 17588 CDRNDAGKYILKLENSSGSKSAFVTVKVLDTPGPPQNLAVKEVRKDSAFLV--WE---PP 17642
Query: 1202 DITGYRITTTPTNGQQGNSLEEVVHAD----QSSCTFDNLSPGLEYNVSVYTVKDDKESV 1257
I G ++ ++ + + ++S +NL+ G Y V + V
Sbjct: 17643 IIDGGAKVKNYVIDKRESTRKAYANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFGVGV 17702
Query: 1258 PIS--DTIIPEVPQLTD--LSFVDITDSSIGLRWTPLN---SSTIIGYRITVVAAGEGIP 1310
P+ D + P ++ D++ +S L W S ++GY V +G
Sbjct: 17703 PVETVDAVKAAEPPSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLGY--VVEMQPKGTE 17760
Query: 1311 IFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTT---------LTQQTAVPPP 1361
+ +S V VTGL G +Y V G+S P LT Q ++ P
Sbjct: 17761 KWSIVAESKVCNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKLP 17820
Query: 1362 TDLRFTNIGPD---TMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTN 1418
+ G D + V P P+I +++ P+K +++ + + VL +
Sbjct: 17821 FNTYSIQAGEDLKIEIPVIGRPRPNI---SWVKDGEPLK---QTTRVNVEETATSTVL-H 17873
Query: 1419 LLPGTE------YVVSVSSVYEQHESTPLRGRQKTGLDSPTG-IDFSDITANSFTVHWIA 1471
+ G + V + +S E+ + +K G P G + F +++A+ + W
Sbjct: 17874 IKEGNKDDFGKYTVTATNSAGTATENLSVIVLEKPG--PPVGPVRFDEVSADFVVISWEP 17931
Query: 1472 PRAT----ITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREE 1527
P T I+ Y + + + +R +I +T L GTEY I A N +
Sbjct: 17932 PAYTGGCQISNYIVEKR-DTTTTTWHMVSATVARTTIKITKLKTGTEYQFRIFAENRYGK 17990
Query: 1528 SPLLIGQQSTVS------DVPRDLEVVAATPTSLLISWDAP----AVTVRYYRITYGETG 1577
S L + V P V + + +L+ W P + Y + E
Sbjct: 17991 SAPLDSKAVIVQYPFKEPGPPGTPFVTSISKDQMLVQWHEPVNDGGTKIIGYHLEQKEKN 18050
Query: 1578 GNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPS 1637
V+ P + +GL G++Y V A G S R D P
Sbjct: 18051 SILWVKLNKTPIQDTKFKTTGLDEGLEYEFKVSAENIVGIGKPSKVSECFVARDPCDPPG 18110
Query: 1638 QMQVTDVQDNSISVKW----LPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGL 1693
+ + + N++++KW S +TGY V K +TE T+ GL
Sbjct: 18111 RPEAIVITRNNVTLKWKKPAYDGGSKITGYIVEKKDLPDGRWMKASFTNVLETEFTVSGL 18170
Query: 1694 QPTVEYVVSVYAQNPSGE-SQPLVQT-AVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVS 1751
Y V A+N +G S+P + A+T D ++D + + + V
Sbjct: 18171 VEDQRYEFRVIARNAAGNFSEPSDSSGAITARD--------EIDAPNASLDPKYKDVIVV 18222
Query: 1752 RYRVTYSSPED----GIHELFPAPDGE--EDTAELQGLRPGSEYTVSVV--ALHDD---- 1799
T+ D I ++ + DG+ E+TA ++ + T VV + D
Sbjct: 18223 HAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQY 18282
Query: 1800 -MESQPLIGTQSTAI-------PAPTD--LKFTQVTPTSLSAQWTPPNVQLTGYRVR--V 1847
++ + GT+S I P P + LK T VT W PP +Q G + +
Sbjct: 18283 ILKLSNVGGTKSIPITVKVLDRPGPPEGPLKVTGVTAEKCYLAWNPP-LQDGGANISHYI 18341
Query: 1848 TPKEKTGPMK--EINLAPDSSSVVVSGLMVATKY-----EVSVYALKDTLTSRPAQGVVT 1900
K +T + +++ + + V+ L+ +Y V+ Y + + L S P
Sbjct: 18342 IEKRETSRLSWTQVSTEVQALNYKVTKLLPGNEYIFRVMAVNKYGIGEPLESGPVT-ACN 18400
Query: 1901 TLENVSPPRRARVTDATETTITISWRTKTE----TITGFQVDAVPANG--QTPIQRTIKP 1954
+ PP V+ T+ ++ ++W + I G+ ++ G T +
Sbjct: 18401 PYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDKEGVRWTKCNKKTLT 18460
Query: 1955 DVRSYTITGLQPGTDYKIYLYTLNDNARSSPV-------VIDASTAIDAPSNLRFLATTP 2007
D+R +TGL G Y+ + N P DA PSN + T+
Sbjct: 18461 DLR-LRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRACDALYPPGPPSNPKVTDTSR 18519
Query: 2008 NSLLVSWQPP----RARITGYIIKYEKPGSPPREVVPRPRPGV--TEATITGLEPGTEYT 2061
+S+ ++W P A + GY+++ K + P G+ + T+T L+ TEY
Sbjct: 18520 SSVSLAWSKPIYDGGAPVKGYVVEV-KEAAADEWTTCTPPTGLQGKQFTVTKLKENTEYN 18578
Query: 2062 IYVIALKNNQKSEP 2075
+ A+ + EP
Sbjct: 18579 FRICAINSEGVGEP 18592
Score = 123 bits (309), Expect = 2e-27
Identities = 314/1502 (20%), Positives = 546/1502 (36%), Gaps = 190/1502 (12%)
Query: 619 TPSQPNSHPIQWNAP---QPSHISKYILRWRPKNSVGRWKEATIPGHLNS--YTIKGLKP 673
T + +S + W+ P + + Y++ + + + W T P L +T+ LK
Sbjct: 18515 TDTSRSSVSLAWSKPIYDGGAPVKGYVVEVK-EAAADEWTTCTPPTGLQGKQFTVTKLKE 18573
Query: 674 GVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITA 733
Y ++ +I G E T + V + P L A V + A
Sbjct: 18574 NTEYNFRICAINSEGVGE------PATLPGSVVAQERIE---PPEIELDADLRKVVVLRA 18624
Query: 734 SSFVVSWVSASDTVSGFRVEYELSEEGDEP-----QYLDLPSTATSVNIPDLLPGRKYIV 788
S+ + +V T+ G R E E+ E E +++ S+ T + I ++
Sbjct: 18625 SATLRLFV----TIKG-RPEPEVKWEKAEGILTDRAQIEVTSSFTMLVIDNVTRFDSGRY 18679
Query: 789 NVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ----APITGYRIV 844
N+ + G ++ ++ +P AP + T+ +V S+ + W P A IT Y +
Sbjct: 18680 NLTLENNSGSKTAFVNVRVLDSPSAPVNLTIREVKKDSVTLSWEPPLIDGGAKITNYIVE 18739
Query: 845 YSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRS 904
+ + + T + + +LQ G Y + A E P ETT +
Sbjct: 18740 KRETTRKAYATITNNCTKTTFRIENLQEGCSYYFRVLASNEYGIGLPA----ETTEPVKV 18795
Query: 905 DTVPSPRD-LQFVEVTDVKVTIMWTPPES----AVTGYRVDVIPVNLPGEHGQRLPISRN 959
P P + V+VT TI W PES +TGY V++ E +
Sbjct: 18796 SEPPLPPGRVTLVDVTRNTATIKWEKPESDGGSKITGYVVEMQTKG--SEKWSTCTQVKT 18853
Query: 960 TFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWT- 1018
A ++GL+ G Y F+V AV+ S P +L P + + S L T
Sbjct: 18854 LEATISGLTAGEEYVFRVAAVNEKGRSDP------RQLGVPVIARDIEIKPSVELPFHTF 18907
Query: 1019 --PPRAQIT-------GYRLTVGLTRRGQP----RQYNVGPSVSKYPLRNLQPASEYTVS 1065
R Q+ + TV + GQ + NV S + L +++ AS+ V
Sbjct: 18908 NVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSL-SIKEASKEDVG 18966
Query: 1066 LVAIKGNQESPKATGVFTTL---QPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPS 1122
+ + + T T + +PG P EV+ +I I+W P G G + S
Sbjct: 18967 TYELCVSNSAGSITVPITIIVLDRPGPPGPIRIDEVSCDSITISWNPPEYDG---GCQIS 19023
Query: 1123 QGGEAPREVTSDSGSIV----------VSGLTPGVEYVYTIQVL-RDGQ----ERDAPIV 1167
+E TS + IV + LT G EY + + R G+ E A +
Sbjct: 19024 NYIVEKKETTSTTWHIVSQAVARTSIKIVRLTTGSEYQFRVCAENRYGKSSYSESSAVVA 19083
Query: 1168 NKVVTPLSPP-TNLHLEANPDTGVLTVSWERSTTPD---ITGYRITTTPTNGQQGNSLEE 1223
+P PP T + A T + V+W+ + GY + + + +
Sbjct: 19084 EYPFSPPGPPGTPKVVHATKST--MLVTWQVPVNDGGSRVIGYHLEYKERSSILWSKANK 19141
Query: 1224 VVHADQSSCTFDNLSPGLEYNVSVYT--------VKDDKESVPISDTIIPE-VPQLTDLS 1274
++ AD + L GL Y VY E VP D P P++T+
Sbjct: 19142 ILIAD-TQMKVSGLDEGLMYEYRVYAENIAGIGKCSKSCEPVPARDPCDPPGQPEVTN-- 19198
Query: 1275 FVDITDSSIGLRWTPLN---SSTIIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPG 1331
IT S+ L+W+ + + I GY + +G + ++ + Y+ VT L
Sbjct: 19199 ---ITRKSVSLKWSKPHYDGGAKITGYIVERRELPDGRWLKCNYTNIQETYFEVTELTED 19255
Query: 1332 IDYDISVI------TLINGGESAPTTLTQQTAVPPPT--DLRFTNI----GPDTMRVT-- 1377
Y+ V ++ ES + + PP D++F ++ + +++
Sbjct: 19256 QRYEFRVFARNAADSVSEPSESTGPIIVKDDVEPPRVMMDVKFRDVIVVKAGEVLKINAD 19315
Query: 1378 --WAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNL----LPGTEYVVSVSS 1431
P P I + E+ A I +DN +LT +YV+++ +
Sbjct: 19316 IAGRPLPVISWAKDGIEI------EERARTEIISTDNHTLLTVKDCIRRDTGQYVLTLKN 19369
Query: 1432 VYEQHE-STPLRGRQKTGLDSPTG-IDFSDITANSFTVHWIAPR----ATITGYRI-RHH 1484
V + + K G P G ++ + +TA ++ W P+ A I Y + +
Sbjct: 19370 VAGTRSVAVNCKVLDKPG--PPAGPLEINGLTAEKCSLSWGRPQEDGGADIDYYIVEKRE 19427
Query: 1485 PEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGR------EESPLLIGQQSTV 1538
H + E + S +T L G EY+ + +N E + TV
Sbjct: 19428 TSHLAWTICEGEL--QMTSCKVTKLLKGNEYIFRVTGVNKYGVGEPLESVAIKALDPFTV 19485
Query: 1539 SDVPRDLEVVAATPTSLLISWDAP----AVTVRYYRITYGETGGNSPVQEFTVPGSKSTA 1594
P LE+ + T S+ + W P + Y I E V+ P
Sbjct: 19486 PSPPTSLEITSVTKESMTLCWSRPESDGGSEISGYIIERREKNSLRWVRVNKKPVYDLRV 19545
Query: 1595 TISGLKPGVDYTITVYAVTGRGDS-PASSKPISINYRTEI---DKPSQMQVTDVQDNSIS 1650
+GL+ G +Y VYA G S P+ + P+ I + PS+ ++ D +I+
Sbjct: 19546 KSTGLREGCEYEYRVYAENAAGLSLPSETSPL-IRAEDPVFLPSPPSKPKIVDSGKTTIT 19604
Query: 1651 VKWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQ 1706
+ W+ +P+TGY V K+ KT TE TI GL EYV V +
Sbjct: 19605 IAWVKPLFDGGAPITGYTVEYK-KSDDTDWKTSIQSLRGTEYTISGLTTGAEYVFRVKSV 19663
Query: 1707 NPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRY---------RVTY 1757
N G S P + + D+D + K + V +
Sbjct: 19664 NKVGASDPSDSSDPQIAKEREEEPLFDIDSEMRKTLIVKAGASFTMTVPFRGRPVPNVLW 19723
Query: 1758 SSPEDGIHELFPAPDGEEDTA---ELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIP 1814
S P+ + + T+ E +YT+++ + ++ T P
Sbjct: 19724 SKPDTDLRTRAYVDTTDSRTSLTIENANRNDSGKYTLTIQNVLSAASLTLVVKVLDTPGP 19783
Query: 1815 APTDLKFTQVTPTSLSAQWTPP----NVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVV 1870
PT++ VT S W P + Y + K + N + S V
Sbjct: 19784 -PTNITVQDVTKESAVLSWDVPENDGGAPVKNYHIEKREASKKAWVSVTNNC-NRLSYKV 19841
Query: 1871 SGLMVATKYEVSVYALKDTLTSRPA---QGVVTTLENVSPPRRARVTDATETTITISW-- 1925
+ L Y V + PA +GV T E SPP + VT ++ +++++W
Sbjct: 19842 TNLQEGAIYYFRVSGENEFGVGIPAETKEGVKIT-EKPSPPEKLGVTSISKDSVSLTWLK 19900
Query: 1926 --RTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARS 1983
I + V+A+ + ++ + + ++GL+ ++Y ++ N S
Sbjct: 19901 PEHDGGSRIVHYVVEALEKGQKNWVKCAVAKSTH-HVVSGLRENSEYFFRVFAENQAGLS 19959
Query: 1984 SP 1985
P
Sbjct: 19960 DP 19961
Score = 120 bits (301), Expect = 2e-26
Identities = 286/1368 (20%), Positives = 511/1368 (37%), Gaps = 206/1368 (15%)
Query: 866 TLSDLQPGVQYNITIYAVEENQEST-PVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVT 924
T++ L G +Y + A EN+ T P + + D P + +V+ ++T
Sbjct: 11859 TVTRLIEGNEYIFRVRA--ENKIGTGPPTESKPVIAKTKYDKPGRPDPPEVTKVSKEEMT 11916
Query: 925 IMWTPPE----SAVTGYRVDVIPVNLPGEHGQR-LPISRNTFAE----VTGLSPGVTYYF 975
++W PPE ++TGY ++ +H R +P++++ E V L P Y F
Sbjct: 11917 VVWNPPEYDGGKSITGYFLEK-----KEKHSTRWVPVNKSAIPERRMKVQNLLPDHEYQF 11971
Query: 976 KVFAVSH------GRESKPLTAQQTTKLDAP-TNLQFVNETDSTVLVRWTPP----RAQI 1024
+V A + S+P+ A+ + P TN + V+ T ++ + W P A I
Sbjct: 11972 RVKAENEIGIGEPSLPSRPVVAKDPIEPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAPI 12031
Query: 1025 TGY------RLTVGLTRRGQPRQYNVGPSVSK-YPLRNLQPASEYTVSL-----VAIKGN 1072
GY ++ G R V K + + +L EY + V I
Sbjct: 12032 IGYVVEMRPKIADASPDEGWKRCNAAAQLVRKEFTVTSLDENQEYEFRVCAQNQVGIGRP 12091
Query: 1073 QESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWT-------------PAPRIGFKLGV 1119
E +A L+P P + + + +VI PAP++ ++
Sbjct: 12092 AELKEAIKPKEILEP----PEIDLDASMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVG 12147
Query: 1120 RPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTN 1179
+ + ++ +V+ T Y++ ++ E+ + +V+ P ++
Sbjct: 12148 IDNVVRKGQVDLVDTMAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFVNVRVLDTPGPVSD 12207
Query: 1180 LHLEANPDTGVLTVSW---ERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDN 1236
L + T VSW E +T Y + + + +++ V ++S N
Sbjct: 12208 LKVSDVTKTSC-HVSWAPPENDGGSQVTHYIVEKREADRKTWSTVTPEVK--KTSFHVTN 12264
Query: 1237 LSPGLEYNVSVYTVKDDKESVPI--------SDTII-PEVPQLTDLSFVDITDSSIGLRW 1287
L PG EY V V + VP SD + P+ P+ L ++T +S L W
Sbjct: 12265 LVPGNEYYFRVTAVNEYGPGVPTDVPKPVLASDPLSEPDPPR--KLEVTEMTKNSATLAW 12322
Query: 1288 TPL---NSSTIIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLING 1344
P + I GY + + + ++ VTGL+ G Y V
Sbjct: 12323 LPPLRDGGAKIDGYITSYREEEQPADRWTEYSVVKDLSLVVTGLKEGKKYKFRVAARNAV 12382
Query: 1345 GESAPTTL-----TQQTAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVK-- 1397
G S P ++ +PP + P+ + + I+ + + K
Sbjct: 12383 GVSLPREAEGVYEAKEQLLPPKI------LMPEQITIKAGKKLRIEAHVYGKPHPTCKWK 12436
Query: 1398 -NEEDV---AELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSP- 1452
E++V + L++ +D++ +L + S E T + + +D+P
Sbjct: 12437 KGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPG 12496
Query: 1453 ---TGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPH----SRNSIT 1505
D SDI A++ ++ W P G I ++ R D V ++ S
Sbjct: 12497 PPQPPFDISDIDADACSLSWHIPLED-GGSNITNYIVEKCDVSRGDWVTALASVTKTSCR 12555
Query: 1506 LTNLTPGTEYVVSIVALN--GREE---SPLLIGQ-QSTVSDVPRDLEVVAATPTSLLISW 1559
+ L PG EY+ + A N G E SP ++ Q V P++ V + ++W
Sbjct: 12556 VGKLIPGQEYIFRVRAENRFGISEPLTSPKMVAQFPFGVPSEPKNARVTKVNKDCIFVAW 12615
Query: 1560 DAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATI----------------SGLKPGV 1603
D P ++ G SP+ + + + + + +GL G+
Sbjct: 12616 DRP------------DSDGGSPIIGYLIERKERNSLLWVKANDTLVRSTEYPCAGLVEGL 12663
Query: 1604 DYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWL----PSSSP 1659
+Y+ +YA+ G SP S + R +D P + +V DV +++S+ W S
Sbjct: 12664 EYSFRIYALNKAGSSPPSKPTEYVTARMPVDPPGKPEVIDVTKSTVSLIWARPKHDGGSK 12723
Query: 1660 VTGYRVTTTPKNGPGPTKTKTAGPD--QTEMTIEGLQPTVEYVVSVYAQN------PSGE 1711
+ GY V G + TA Q E T GL+ +Y A+ PS
Sbjct: 12724 IIGYFVEACKLPGDKWVRCNTAPHQIPQEEYTATGLEEKAQYQFRAIARTAVNISPPSEP 12783
Query: 1712 SQP---LVQTAVTNIDRPKGL-------AFTDVDVDSIKIAWESPQGQVS-RYRVTYSSP 1760
S P L + ID + A T+V +D+ + P VS + T P
Sbjct: 12784 SDPVTILAENVPPRIDLSVAMKSLLTVKAGTNVCLDA--TVFGKPMPTVSWKKDGTLLKP 12841
Query: 1761 EDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPA-PTDL 1819
+GI A T EL + ++ A + I + P P +
Sbjct: 12842 AEGIK---MAMQRNLCTLELFSVNRKDSGDYTITAENSSGSKSATIKLKVLDKPGPPASV 12898
Query: 1820 KFTQVTPTSLSAQWTPP----NVQLTGYRVRVTPKEKTGP-MKEINLAPDSSSVVVSGLM 1874
K ++ W PP ++T Y V +E + P +++ +S V L+
Sbjct: 12899 KINKMYSDRAMLSWEPPLEDGGSEITNY--IVDKRETSRPNWAQVSATVPITSCSVEKLI 12956
Query: 1875 VATKYEVSV-----YALKDTLTSRPAQGVVTTLENVSPPRRAR---VTDATETTITISWR 1926
+Y+ + Y + D + + PA PP R +++ T+ +T+SW+
Sbjct: 12957 EGHEYQFRICAENKYGVGDPVFTEPA----IAKNPYDPPGRCDPPVISNITKDHMTVSWK 13012
Query: 1927 TKTE----TITGFQVDAVPANGQTPIQRTIKPDV-RSYTITGLQPGTDYKIYLYTLNDNA 1981
+ ITG+ ++ + KP + R+ TGLQ GT+Y+ + +N
Sbjct: 13013 PPADDGGSPITGYLLEKRETQAVNWTKVNRKPIIERTLKATGLQEGTEYEFRVTAINKAG 13072
Query: 1982 RSSPVVIDASTAIDA---------PSNLRFLATTPNSLLVSWQPPR----ARITGYIIKY 2028
P DAS A A P+ + TT +S+ +SW P + I GY+++
Sbjct: 13073 PGKP--SDASKAAYARDPQYPPGPPAFPKVYDTTRSSVSLSWGKPAYDGGSPIIGYLVEV 13130
Query: 2029 EKPGSPPREVVPRPRP-GVTEATITGLEPGTEYTIYVIALKNNQKSEP 2075
++ S P+ T +TGL T+Y V A+ S+P
Sbjct: 13131 KRADSDNWVRCNLPQNLQKTRFEVTGLMEDTQYQFRVYAVNKIGYSDP 13178
Score = 120 bits (301), Expect = 2e-26
Identities = 304/1512 (20%), Positives = 534/1512 (35%), Gaps = 204/1512 (13%)
Query: 718 FSPLVATSESVTEITASSFVVSW----VSASDTVSGFRVEYELSEEGDEPQYLDLPSTA- 772
F P T+ + + T +S ++W + G+ VE + + +E + P T
Sbjct: 17421 FKPGPPTNAHIVDTTKNSITLAWGKPIYDGGSEILGYVVE--ICKADEEEWQIVTPQTGL 17478
Query: 773 --TSVNIPDLLPGRKYIVNVYQISEDG--EQSLILSTSQTTAPDAPPDPTVDQVDDTSIV 828
T I L ++Y + V +++ G E + + T + P+ +D IV
Sbjct: 17479 RVTRFEISKLTEHQEYKIRVCALNKVGLGEATSVPGTVKPEDKLEAPELDLDSELRKGIV 17538
Query: 829 VRW---SRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYN-ITIYAVE 884
VR +R P G +P + S E + ++ GV Y ++I +
Sbjct: 17539 VRAGGSARIHIPFKGRP---TPEITWSREEGEFTDKVQ------IEKGVNYTQLSIDNCD 17589
Query: 885 ENQESTPVVIQQETTGTPRS-------DTVPSPRDLQFVEVTDVKVTIMWTPP----ESA 933
N ++ + ++G+ + DT P++L EV ++W PP +
Sbjct: 17590 RNDAGKYILKLENSSGSKSAFVTVKVLDTPGPPQNLAVKEVRKDSAFLVWEPPIIDGGAK 17649
Query: 934 VTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQ 993
V Y +D S+ +F +V L+ G YYF+V A + P+
Sbjct: 17650 VKNYVIDKRESTRKAYANVSSKCSKTSF-KVENLTEGAIYYFRVMAENEFGVGVPVETVD 17708
Query: 994 TTKLDAPTN------LQFVNETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYN 1043
K P + L V++T ++++ W P +++ GY V + +G +
Sbjct: 17709 AVKAAEPPSPPGKVTLTDVSQTSASLM--WEKPEHDGGSRVLGY--VVEMQPKGTEKWSI 17764
Query: 1044 VGPS-VSKYPLRNLQPASEYTVSLVAIKGNQES-PKATGVFT-----TLQPGSSIPPYNT 1096
V S V + L EY + A +S P+ GV T+QP +P +NT
Sbjct: 17765 VAESKVCNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKLP-FNT 17823
Query: 1097 ------EVTETTIVITWTPAPRIGF-KLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEY 1149
E + I + P P I + K G Q E T+ S + +
Sbjct: 17824 YSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFG 17883
Query: 1150 VYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTP---DITGY 1206
YT+ + V+ PP + +SWE I+ Y
Sbjct: 17884 KYTVTATNSAGTATENLSVIVLEKPGPPVGPVRFDEVSADFVVISWEPPAYTGGCQISNY 17943
Query: 1207 RITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTII-- 1264
+ T + + V +++ L G EY ++ +S P+ +
Sbjct: 17944 IVEKRDTTTTTWHMVSATVA--RTTIKITKLKTGTEYQFRIFAENRYGKSAPLDSKAVIV 18001
Query: 1265 ---------PEVPQLTDLSFVDITDSSIGLRW-TPLNS--STIIGYRITVVAAGEGIPIF 1312
P P +T +S + ++W P+N + IIGY + + +
Sbjct: 18002 QYPFKEPGPPGTPFVTSIS-----KDQMLVQWHEPVNDGGTKIIGYHLEQKEKNSILWVK 18056
Query: 1313 EDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQ----QTAVPPPTDLRFTN 1368
+ + TGL+ G++Y+ V G P+ +++ + PP
Sbjct: 18057 LNKTPIQDTKFKTTGLDEGLEYEFKVSAENIVGIGKPSKVSECFVARDPCDPPGRPEAIV 18116
Query: 1369 IGPDTMRVTWAPPP---SIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEY 1425
I + + + W P +T ++V K+ D + S TN+L TE+
Sbjct: 18117 ITRNNVTLKWKKPAYDGGSKITGYIVEK---KDLPDGRWMKAS-------FTNVLE-TEF 18165
Query: 1426 VVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITG-YR---I 1481
VS V +Q + R G S ITA AP A++ Y+ +
Sbjct: 18166 TVS-GLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARD---EIDAPNASLDPKYKDVIV 18221
Query: 1482 RHHPEHF------SGRPREDRV--------------PHSRNSITLTNL-------TPGTE 1514
H E F G+P D V +++I T L T G +
Sbjct: 18222 VHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQ 18281
Query: 1515 YVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAP----AVTVRYYR 1570
Y++ + + G + P+ + L+V T ++W+ P + +Y
Sbjct: 18282 YILKLSNVGGTKSIPITVKVLDRPGPPEGPLKVTGVTAEKCYLAWNPPLQDGGANISHYI 18341
Query: 1571 ITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRG-DSPASSKPISI-N 1628
I ET S Q T + + ++ L PG +Y V AV G P S P++ N
Sbjct: 18342 IEKRETSRLSWTQVSTEVQALNYK-VTKLLPGNEYIFRVMAVNKYGIGEPLESGPVTACN 18400
Query: 1629 YRTEIDKPSQMQVTDVQDNSISVKWL----PSSSPVTGYRVTTTPKNGPGPTKTKTAGPD 1684
PS +V+ + +S+ V W + + GY + K G TK
Sbjct: 18401 PYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDKEGVRWTKCNKKTLT 18460
Query: 1685 QTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQT-------AVTNIDRPKGLAFTDVDVD 1737
+ + GL Y V A+N +G +P + A+ P TD
Sbjct: 18461 DLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRACDALYPPGPPSNPKVTDTSRS 18520
Query: 1738 SIKIAWESP----QGQVSRYRVTYSSPEDGIHELFPAPDGEEDTA-ELQGLRPGSEYTVS 1792
S+ +AW P V Y V P G + + L+ +EY
Sbjct: 18521 SVSLAWSKPIYDGGAPVKGYVVEVKEAAADEWTTCTPPTGLQGKQFTVTKLKENTEYNFR 18580
Query: 1793 VVALHDDMESQPL-----IGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRV 1847
+ A++ + +P + Q P +L L A T R+ V
Sbjct: 18581 ICAINSEGVGEPATLPGSVVAQERIEPPEIELDADLRKVVVLRASAT--------LRLFV 18632
Query: 1848 TPKEKTGPM----KEINLAPDSSSVVVSGLMV------ATKYEVSVY--ALKDTLTSRPA 1895
T K + P K + D + + V+ T+++ Y L++ S+ A
Sbjct: 18633 TIKGRPEPEVKWEKAEGILTDRAQIEVTSSFTMLVIDNVTRFDSGRYNLTLENNSGSKTA 18692
Query: 1896 QGVVTTLENVSPPRRARVTDATETTITISWRTKT----ETITGFQVDAVPANGQTPIQRT 1951
V L++ S P + + + ++T+SW IT + V+ + T
Sbjct: 18693 FVNVRVLDSPSAPVNLTIREVKKDSVTLSWEPPLIDGGAKITNYIVEKRETTRKAYATIT 18752
Query: 1952 IKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAP----SNLRFLATTP 2007
++ I LQ G Y + N+ P + P + + T
Sbjct: 18753 NNCTKTTFRIENLQEGCSYYFRVLASNEYGIGLPAETTEPVKVSEPPLPPGRVTLVDVTR 18812
Query: 2008 NSLLVSWQPPRA----RITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIY 2063
N+ + W+ P + +ITGY+++ + GS + + EATI+GL G EY
Sbjct: 18813 NTATIKWEKPESDGGSKITGYVVEMQTKGSEKWSTCTQVK--TLEATISGLTAGEEYVFR 18870
Query: 2064 VIALKNNQKSEP 2075
V A+ +S+P
Sbjct: 18871 VAAVNEKGRSDP 18882
Score = 119 bits (298), Expect = 4e-26
Identities = 329/1550 (21%), Positives = 553/1550 (35%), Gaps = 222/1550 (14%)
Query: 601 PLQTYPSSSGPVEVFITETPSQPN-------SHPIQWNAPQ---PSHISKYILRWRPKNS 650
P +T P VF+ PS+P + I W P + I+ Y + ++ +
Sbjct: 19571 PSETSPLIRAEDPVFLPSPPSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEYKKSDD 19630
Query: 651 VGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNT 710
WK + YTI GL G Y ++ S+ + G + + +S P +
Sbjct: 19631 TD-WKTSIQSLRGTEYTISGLTTGAEYVFRVKSVNKVGASD-------PSDSSDPQIAKE 19682
Query: 711 VTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVS--GFRVEYELSEEGDEP----Q 764
E PL +E+ + V + S + TV G V L + D
Sbjct: 19683 REEE-----PLFDID---SEMRKTLIVKAGASFTMTVPFRGRPVPNVLWSKPDTDLRTRA 19734
Query: 765 YLDLPSTATSVNIPDLL--PGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQV 822
Y+D + TS+ I + KY + + + +L++ T P P + TV V
Sbjct: 19735 YVDTTDSRTSLTIENANRNDSGKYTLTIQNVLSAASLTLVVKVLDTPGP--PTNITVQDV 19792
Query: 823 DDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNI 878
S V+ W P+ AP+ Y I + + + + S +++LQ G Y
Sbjct: 19793 TKESAVLSWDVPENDGGAPVKNYHIEKREASKKAWVSVTNNCNRLSYKVTNLQEGAIYYF 19852
Query: 879 TIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAV 934
+ E P ++ G ++ P L ++ V++ W PE S +
Sbjct: 19853 RVSGENEFGVGIPAETKE---GVKITEKPSPPEKLGVTSISKDSVSLTWLKPEHDGGSRI 19909
Query: 935 TGYRVDVIPVNLPGEHGQR----LPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKP-- 988
Y V+ + E GQ+ ++++T V+GL Y+F+VFA + S P
Sbjct: 19910 VHYVVEAL------EKGQKNWVKCAVAKSTHHVVSGLRENSEYFFRVFAENQAGLSDPRE 19963
Query: 989 -LTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPS 1047
L + P + N TV VR G L V + G+P V S
Sbjct: 19964 LLLPVLIKEQLEPPEIDMKNFPSHTVYVR--------AGSNLKVDIPISGKPLP-KVTLS 20014
Query: 1048 VSKYPLR-NLQPASEYTV---------SLVAIKGNQESPKATGVFTTL---------QPG 1088
PL+ ++ +E T S+ A G E A TT +PG
Sbjct: 20015 RDGVPLKATMRFNTEITAENLTINLKESVTADAGRYEITAANSSGTTKAFINIVVLDRPG 20074
Query: 1089 SSI-PPYNTEVTETTIVITWTPAPRIG-------FKLGVRPSQGGEAPREVTSDSGSIVV 1140
P +++TE ++ + W P G L S T + V
Sbjct: 20075 PPTGPVVISDITEESVTLKWEPPKYDGGSQVTNYILLKRETSTAVWTEVSATVARTMMKV 20134
Query: 1141 SGLTPGVEYVYTIQV-----LRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSW 1195
LT G EY + I+ + D + V T PP+ + N +TV W
Sbjct: 20135 MKLTTGEEYQFRIKAENRFGISDHIDSACVTVKLPYTTPGPPSTPWV-TNVTRESITVGW 20193
Query: 1196 ERSTT---PDITGYRITTTPTNG---QQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYT 1249
+ + GY + N Q+ N L V+ T +S GL Y VY
Sbjct: 20194 HEPVSNGGSAVVGYHLEMKDRNSILWQKANKL--VIRTTHFKVT--TISAGLIYEFRVYA 20249
Query: 1250 V------KDDKESVPISDTIIPEVPQLTDLSFVDITDSSIGLRWTPL---NSSTIIGYRI 1300
K S P+ E P+ ++ DI+ +S+ L W S I GY +
Sbjct: 20250 ENAAGVGKPSHPSEPVLAIDACEPPR--NVRITDISKNSVSLSWQQPAFDGGSKITGYIV 20307
Query: 1301 TVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISV------------------ITLI 1342
+G F + + + ++GL Y+ V IT I
Sbjct: 20308 ERRDLPDGRWTKASFTNVTETQFIISGLTQNSQYEFRVFARNAVGSISNPSEVVGPITCI 20367
Query: 1343 N--GGE--SAPTTLTQQTAVPPPTD--LRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPV 1396
+ GG P T+ T LR G + W TN LV V
Sbjct: 20368 DSYGGPVIDLPLEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALV---CV 20424
Query: 1397 KNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTG-I 1455
+N D+A + I +D L Y + + + +T +R + P G I
Sbjct: 20425 ENTTDLASILIKDADR-------LNSGCYELKLRNAMGSASAT-IRVQILDKPGPPGGPI 20476
Query: 1456 DFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNS-------ITLTN 1508
+F +TA T+ W P A G +I H + + RV S S IT T
Sbjct: 20477 EFKTVTAEKITLLW-RPPADDGGAKITH---YIVEKRETSRVVWSMVSEHLEECIITTTK 20532
Query: 1509 LTPGTEYVVSIVALNGRE-----ESPLLIGQQSTVSDVPRDL-EVVAATPTSLLISWDAP 1562
+ G EY+ + A+N ES ++ + + V+ P + EV T S+ + W P
Sbjct: 20533 IIKGNEYIFRVRAVNKYGIGEPLESDSVVAKNAFVTPGPPGIPEVTKITKNSMTVVWSRP 20592
Query: 1563 A------VTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRG 1616
++ + ++ G V + T+ ++ T GL DY V AV G
Sbjct: 20593 IADGGSDISGYFLEKRDKKSLGWFKVLKETIRDTRQKVT--GLTENSDYQYRVCAVNAAG 20650
Query: 1617 DSPASSKPISINYRTEID---KPSQMQVTDVQDNSISVKW----LPSSSPVTGYRVTTTP 1669
P S ID P+++++ D +SI++ W S VTGY V
Sbjct: 20651 QGPFSEPSEFYKAADPIDPPGPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVVEIRQ 20710
Query: 1670 KNGPGPTKTKTAGPDQ-TEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKG 1728
T T G + TE + L+P V Y V A N +G+ +P+ +
Sbjct: 20711 GEEEEWTTVSTKGEVRTTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMN--EPVQAKDI 20768
Query: 1729 LAFTDVDVD-SIKIAWESPQGQVSRYRVTYSS--PEDGIHELFPAPDGEEDTAELQGLRP 1785
L ++D+D +++ + + G+ + + + P G + ++
Sbjct: 20769 LEAPEIDLDVALRTSVIAKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYSIENTDS 20828
Query: 1786 GSEYTVSVVALHDDME---------SQPLIGTQSTAI----PAPTDLKFTQVTPTSLSAQ 1832
S T+ V +D + +P T S + A L+ V+ +++
Sbjct: 20829 SSLLTIPQVTRNDTGKYILTIENGVGEPKSSTVSVKVLDTPAACQKLQVKHVSRGTVTLL 20888
Query: 1833 WTPPNVQLTGYRVRVTPKEKTGPMKEINLAP---DSSSVVVSGLMVATKYEVSVYALKDT 1889
W PP + + +++ + ++ S+S + L T + V A +
Sbjct: 20889 WDPPLIDGGSPIINYVIEKRDATKRTWSVVSHKCSSTSFKLIDLSEKTPFFFRVLAENEI 20948
Query: 1890 LTSRPAQGV--VTTLENVSPPRRARVTDATETTITISWRTKTE-----TITGFQVDAVPA 1942
P + V E +P R + D+T+T++ +SW TK + IT + V+
Sbjct: 20949 GIGEPCETTEPVKAAEVPAPIRDLSMKDSTKTSVILSW-TKPDFDGGSVITEYVVERKGK 21007
Query: 1943 NGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDAST 1992
QT I ++ L+ + + ++ N+ S PV I T
Sbjct: 21008 GEQTWSHAGISKTC-EIEVSQLKEQSVLEFRVFAKNEKGLSDPVTIGPIT 21056
Score = 118 bits (296), Expect = 6e-26
Identities = 330/1625 (20%), Positives = 588/1625 (36%), Gaps = 230/1625 (14%)
Query: 611 PVEVFITETPSQPNSHPIQWNAP---QPSHISKYILRWRPKNSVGRWKEATIPGHLNSYT 667
PV V + E +S + W P S I Y+++ R W T S+
Sbjct: 13293 PVNVTVKEISK--DSAYVTWEPPIIDGGSPIINYVVQKRDAERKS-WSTVTTECSKTSFR 13349
Query: 668 IKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSES 727
+ L+ G Y ++ + +YG + T + V TP P+V
Sbjct: 13350 VANLEEGKSYFFRVFAENEYGIGDPGE------------TRDAVKASQTP-GPVVDLK-- 13394
Query: 728 VTEITASSFVVSWVS----ASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPG 783
V ++ SS + W + G+ V++ L+EE + + S + + DL G
Sbjct: 13395 VRSVSKSSCSIGWKKPHSDGGSRIIGYVVDF-LTEENKWQRVMK--SLSLQYSAKDLTEG 13451
Query: 784 RKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWS---RPQAPITG 840
++Y V +E+GE + T PD + + D + + + R + PI G
Sbjct: 13452 KEYTFRVSAENENGEGTPSEITVVARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPIKG 13511
Query: 841 YRIVYSPSVE--------GSSTELNLPETANSVTLS--DLQPGV--QYNITIYAVEENQE 888
+PSV + T +++ +A + TL D Q +Y IT+ V +E
Sbjct: 13512 KP---APSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKE 13568
Query: 889 STPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPV 944
T I + G P T P ++F EVT +T+ W PP+ S +T Y ++
Sbjct: 13569 GT---ISIKVVGKPGIPTGP----IKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRD- 13620
Query: 945 NLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKV-----FAVSHGRESKPLTAQQTTKL-D 998
++ + + T VT L G+ Y F+V + V G +S+P+ A+ + D
Sbjct: 13621 SVNNKWVTCASAVQKTTFRVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVPD 13680
Query: 999 APTNLQFVNETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGP-SVSKYPL 1053
AP V+ +V + WT P+ + ITGY L ++ N P + + +
Sbjct: 13681 APPPPNIVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTPIRMRDFKV 13740
Query: 1054 RNLQPASEYTVSLVAI------KGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITW 1107
L EY ++AI K + S + PG P +T ++ + W
Sbjct: 13741 TGLTEGLEYEFRVMAINLAGVGKPSLPSEPVVALDPIDPPGK---PEVINITRNSVTLIW 13797
Query: 1108 T-PAPRIGFKL-------GVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDG 1159
T P G KL PS+ V + V+ L G +Y + I+
Sbjct: 13798 TEPKYDGGHKLTGYIVEKRDLPSKSWMKANHVNVPECAFTVTDLVEGGKYEFRIRAKNTA 13857
Query: 1160 QERDAPIVN----------KVVTPLSPPT---NLHLEANPDTGVLTV-----------SW 1195
AP + + T + PT L ++A DT VL SW
Sbjct: 13858 GAISAPSESTETIICKDEYEAPTIVLDPTIKDGLTIKAG-DTIVLNAISILGKPLPKSSW 13916
Query: 1196 ERS----TTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVK 1251
++ DIT +IT+TPT+ +++ D T +P + K
Sbjct: 13917 SKAGKDIRPSDIT--QITSTPTSSML--TIKYATRKDAGEYTITATNP--------FGTK 13964
Query: 1252 DDKESVPISDTIIPEVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGEGIPI 1311
+ V + D +P P ++S +++ L WTP + ++ E +
Sbjct: 13965 VEHVKVTVLD--VPGPPGPVEIS--NVSAEKATLTWTPPLEDGGSPIKSYILEKRETSRL 14020
Query: 1312 FEDFVDSSVG--YYTVTGLEPGIDYDISVITLINGG-----ESAPTTLTQQTAVP-PPTD 1363
V + + T L G +Y V + + G +S P + + P PP
Sbjct: 14021 LWTVVSEDIQSCRHVATKLIQGNEYIFRVSAVNHYGKGEPVQSEPVKMVDRFGPPGPPEK 14080
Query: 1364 LRFTNIGPDTMRVTWAPP---PSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLL 1420
+N+ +T V+W P ++T + V K+ V + SD +T L
Sbjct: 14081 PEVSNVTKNTATVSWKRPVDDGGSEITGYHVERREKKSLRWVRAIKTPVSDLRCKVTGLQ 14140
Query: 1421 PGTEYVVSVSSVYEQHESTPLRGRQKTGLDS-------PTGIDFSDITANSFTVHWIAPR 1473
G+ Y VS+ P + P+ +D T S ++ W P
Sbjct: 14141 EGSTYEFRVSAENRAGIGPPSEASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLAWGKPH 14200
Query: 1474 ----ATITGYRIRHHPEHFSGRPREDRVPHSR-NSITLTNLTPGTEYVVSIVALN--GRE 1526
ITGY + H ++ R + +L +Y I A+N G
Sbjct: 14201 YDGGLEITGYVVEHQKVGDEAWIKDTTGTALRITQFVVPDLQTKEKYNFRISAINDAGVG 14260
Query: 1527 ESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFT 1586
E ++ + ++ D E+ A +L++ +++R + G P E T
Sbjct: 14261 EPAVIPDVEIVEREMAPDFELDAELRRTLVV---RAGLSIRIFVPIKGR-----PAPEVT 14312
Query: 1587 -VPGSKSTATISGLKPGVDYTITVYAVTGRGD---------SPASSKPISINYRTEIDKP 1636
+ + + ++ +T+ + R D +PA K +N R +D P
Sbjct: 14313 WTKDNINLKNRANIENTESFTLLIIPECNRYDTGKFVMTIENPAGKKSGFVNVRV-LDTP 14371
Query: 1637 S---QMQVTDVQDNSISVKW----LPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMT 1689
++ TD+ +S+++ W + S +T Y V T T +
Sbjct: 14372 GPVLNLRPTDITKDSVTLHWDLPLIDGGSRITNYIVEKREATRKS-YSTATTKCHKCTYK 14430
Query: 1690 IEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDR----PKGLAFTDVDVDSIKIAWES 1745
+ GL EY V A+N G +P T P L D+ ++ +AW
Sbjct: 14431 VTGLSEGCEYFFRVMAENEYGIGEPTETTEPVKASEAPSPPDSLNIMDITKSTVSLAWPK 14490
Query: 1746 PQ----GQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHD--- 1798
P+ +++ Y + G E ++ L G EYT V+A++
Sbjct: 14491 PKHDGGSKITGYVIEAQRKGSDQWTHITTVKGLE--CVVRNLTEGEEYTFQVMAVNSAGR 14548
Query: 1799 --DMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPM 1856
ES+P+I + T +P Q + + + + G R + T K G
Sbjct: 14549 SAPRESRPVIVKEQTMLPELDLRGIYQKLVIAKAGDNIKVEIPVLG-RPKPTVTWKKGDQ 14607
Query: 1857 -----KEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVS----- 1906
+ +N ++S +++ + + + Y LT+R G V + +
Sbjct: 14608 ILKQTQRVNFETTATSTILN-INECVRSDSGPY----PLTARNIVGEVGDVITIQVHDIP 14662
Query: 1907 --PPRRARVTDATETTITISWRTKTE----TITGFQVDAVPANGQTPIQRTIKPDVRSYT 1960
P + + + +T SW I+ + V+ + T ++ +Y
Sbjct: 14663 GPPTGPIKFDEVSSDFVTFSWDPPENDGGVPISNYVVEMRQTDSTTWVELATTVIRTTYK 14722
Query: 1961 ITGLQPGTDYKIYL-----YTLNDNARSSPVVIDASTAIDAPSNL-RFLATTPNSLLVSW 2014
T L G +Y+ + Y + S+ +V + + P + A T +S+ +SW
Sbjct: 14723 ATRLTTGLEYQFRVKAQNRYGVGPGITSACIVANYPFKVPGPPGTPQVTAVTKDSMTISW 14782
Query: 2015 QPP----RARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNN 2070
P + I GY ++ ++ + V + +GL G Y VIA
Sbjct: 14783 HEPLSDGGSPILGYHVERKERNGILWQTVSKALVPGNIFKSSGLTDGIAYEFRVIAENMA 14842
Query: 2071 QKSEP 2075
KS+P
Sbjct: 14843 GKSKP 14847
Score = 116 bits (291), Expect = 2e-25
Identities = 288/1381 (20%), Positives = 498/1381 (36%), Gaps = 191/1381 (13%)
Query: 766 LDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDT 825
+D + TS I + G K + ++ G+ ++ P + V + D
Sbjct: 6548 IDTTAEQTSFRILEAKKGDKGRYKIVLQNKHGKAEGFINLKVIDVPGPVRNLEVTETFDG 6607
Query: 826 SIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETAN-SVTLSDLQPG-VQYNIT 879
+ + W P + I GY +V ++ + L + T++ LQ G V+Y
Sbjct: 6608 EVSLAWEEPLTDGGSKIIGY-VVERRDIKRKTWVLATDRAESCEFTVTGLQKGGVEYLFR 6666
Query: 880 IYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVT 935
+ A PV + D P ++ +V V++ W PPE + +T
Sbjct: 6667 VSARNRVGTGEPVETDNPVEARSKYDVPGPPLNVTITDVNRFGVSLTWEPPEYDGGAEIT 6726
Query: 936 GYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTT 995
Y +++ + + A VT + G Y F+V A + KP A
Sbjct: 6727 NYVIELRDKTSIRWDTAMTVRAEDLSATVTDVVEGQEYSFRVRAQNRIGVGKPSAATPFV 6786
Query: 996 KL-------DAPTNLQFVNETDSTVLVRWTPP----RAQITGYRLTVGLTRRGQPR---- 1040
K+ P NL ++T S+V ++W PP + I GY + G+
Sbjct: 6787 KVADPIERPSPPVNLTSSDQTQSSVQLKWEPPLKDGGSPILGY--IIERCEEGKDNWIRC 6844
Query: 1041 QYNVGPSVSKYPLRNLQPASE--YTVSLVAIKGNQESPKATGVFTT----LQPGSSIPPY 1094
+ P ++ Y + L+ ++ Y VS G + + G T ++P + +
Sbjct: 6845 NMKLVPELT-YKVTGLEKGNKYLYRVSAENKAGVSDPSEILGPLTADDAFVEPTMDLSAF 6903
Query: 1095 NTEV-----TETTIVI--TWTPAPRIGFKLGVRPSQGGEAPREVT-SDSGSIVVSGLTPG 1146
+ TI++ T P P + G + + G+ + T S +V+S
Sbjct: 6904 KDGLEVIVPNPITILVPSTGYPRPTATWCFGDKVLETGDRVKMKTLSAYAELVISPSERS 6963
Query: 1147 VEYVYTIQVLRDGQERDAPI-VNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPD--- 1202
+ +YT+++ + I VN + P +P + D+ LT WE PD
Sbjct: 6964 DKGIYTLKLENRVKTISGEIDVNVIARPSAPKELKFGDITKDSVHLT--WE---PPDDDG 7018
Query: 1203 ---ITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSV------------ 1247
+TGY + + + + + V T +L G EY V
Sbjct: 7019 GSPLTGYVVEKREVSRKTWTKVMDFV--TDLEFTVPDLVQGKEYLFKVCARNKCGPGEPA 7076
Query: 1248 YTVKDDKESVPISDTIIPEVPQLTDLSFVDITDSSIGLRWTPLNS---STIIGYRITVVA 1304
Y + S P + +P+ P+ ++ + D T +SI L W P + S I GY +
Sbjct: 7077 YVDEPVNMSTPAT---VPDPPE--NVKWRDRTANSIFLTWDPPKNDGGSRIKGYIVERCP 7131
Query: 1305 AGE------GIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQ--- 1355
G G P+ E ++ VTGLE G Y V L G S P+ T++
Sbjct: 7132 RGSDKWVACGEPVAETKME-------VTGLEEGKWYAYRVKALNRQGASKPSRPTEEIQA 7184
Query: 1356 --TAVPPPTDLRFTNIGPDTMR----------VTWAPPPSIDLTNFLVRYSPVKNEEDVA 1403
T P L + T++ VT P P I T + + ++
Sbjct: 7185 VDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWT----KADMILKQDKRI 7240
Query: 1404 ELSISPSDNAVVLTNLL---PGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDI 1460
+ P + V + + GT + +V+ + K G P D +D+
Sbjct: 7241 TIENVPKKSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNVLDKPG--PPAAFDITDV 7298
Query: 1461 TANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRNS------ITLTNLT 1510
T S + W PR + IT Y + R + V H +S T L
Sbjct: 7299 TNESCLLTWNPPRDDGGSKITNYVVER-------RATDSEVWHKLSSTVKDTNFKATKLI 7351
Query: 1511 PGTEYVVSIVALN------GREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAP-- 1562
P EY+ + A N + SP+ Q P LE T ++ ++W P
Sbjct: 7352 PNKEYIFRVAAENMYGVGEPVQASPITAKYQFDPPGPPTRLEPSDITKDAVTLTWCEPDD 7411
Query: 1563 --AVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYA--VTGRGDS 1618
+ Y + + + V+ +P +T + GL Y V A + G G
Sbjct: 7412 DGGSPITGYWVERLDPDTDKWVRCNKMPVKDTTYRVKGLTNKKKYRFRVLAENLAGPGKP 7471
Query: 1619 PASSKPISINYRTEID---KPSQMQVTDVQDNSISVKWL----PSSSPVTGYRVTTTPKN 1671
S++PI I + ID P + V DV S+ + W + + Y V K
Sbjct: 7472 SKSTEPILI--KDPIDPPWPPGKPTVKDVGKTSVRLNWTKPEHDGGAKIESY-VIEMLKT 7528
Query: 1672 GPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQP-------LVQTAVTNID 1724
G G T+ + GL EY V A N +GES+P L + +
Sbjct: 7529 GTDEWVRVAEGVPTTQHLLPGLMEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPS 7588
Query: 1725 RPKGLAFTDVDVDSIKIAWESPQ----GQVSRYRVTYSSPEDGIHELFPAPDG--EEDTA 1778
P+ L ++ ++ + W P+ ++ Y V D + + D ++
Sbjct: 7589 PPRWLEVINITKNTADLKWTVPEKDGGSPITNYIV---EKRDVRRKGWQTVDTTVKDTKC 7645
Query: 1779 ELQGLRPGSEYTVSVVAL-------HDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSA 1831
+ L GS Y V A + ++E L T P L VT +
Sbjct: 7646 TVTPLTEGSLYVFRVAAENAIGQSDYTEIEDSVLAKDTFTTPGPPYALAVVDVTKRHVDL 7705
Query: 1832 QWTPPNVQ--LTGYRVRVTPKEKTGP--MKEINLAPDSSSVVVSGLMVATKYEVSVYALK 1887
+W PP R + KE+ G +K A + V+ ++ T+ + V A
Sbjct: 7706 KWEPPKNDGGRPIQRYVIEKKERLGTRWVKAGKTAGPDCNFRVTDVIEGTEVQFQVRAEN 7765
Query: 1888 DTLTSRPAQGV-VTTLEN----VSPPRRARVTDATETTITISWRTKTET----ITGFQVD 1938
+ P++ + ++E+ SPP VTDA I I+W+ + I G+ V+
Sbjct: 7766 EAGVGHPSEPTEILSIEDPTSPPSPPLDLHVTDAGRKHIAIAWKPPEKNGGSPIIGYHVE 7825
Query: 1939 AVPANGQTPIQRTIKP--DVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDA 1996
P + ++ +P D++ G+ P +Y + + +N S P I +
Sbjct: 7826 MCPVGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAIGVSEPSEISENVVAKD 7885
Query: 1997 P 1997
P
Sbjct: 7886 P 7886
Score = 115 bits (287), Expect = 7e-25
Identities = 286/1430 (20%), Positives = 524/1430 (36%), Gaps = 172/1430 (12%)
Query: 785 KYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPT-VDQVDDTSIVVRWSRPQ----APIT 839
+Y++ + ++ G +S+ ++ P P P ++ + + W RPQ A I
Sbjct: 19362 QYVLTLKNVA--GTRSVAVNCKVLDKPGPPAGPLEINGLTAEKCSLSWGRPQEDGGADID 19419
Query: 840 GYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETT 899
Y + + + T S ++ L G +Y + V + P+ E+
Sbjct: 19420 YYIVEKRETSHLAWTICEGELQMTSCKVTKLLKGNEYIFRVTGVNKYGVGEPL----ESV 19475
Query: 900 GTPRSD--TVPSP-RDLQFVEVTDVKVTIMWTPPES----AVTGYRVDVIPVN-LPGEHG 951
D TVPSP L+ VT +T+ W+ PES ++GY ++ N L
Sbjct: 19476 AIKALDPFTVPSPPTSLEITSVTKESMTLCWSRPESDGGSEISGYIIERREKNSLRWVRV 19535
Query: 952 QRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNL-------Q 1004
+ P+ + + TGL G Y ++V+A + S P + + P L +
Sbjct: 19536 NKKPVY-DLRVKSTGLREGCEYEYRVYAENAAGLSLPSETSPLIRAEDPVFLPSPPSKPK 19594
Query: 1005 FVNETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPAS 1060
V+ +T+ + W P A ITGY + + + ++Y + L +
Sbjct: 19595 IVDSGKTTITIAWVKPLFDGGAPITGYTVEYKKSDDTDWKTSIQSLRGTEYTISGLTTGA 19654
Query: 1061 EYTVSLVAIK---GNQESPKATGVFTTLQPGSSIPPYNTEVTETTIV-----ITWT---- 1108
EY + ++ + S + + + ++E+ +T IV T T
Sbjct: 19655 EYVFRVKSVNKVGASDPSDSSDPQIAKEREEEPLFDIDSEMRKTLIVKAGASFTMTVPFR 19714
Query: 1109 --PAPRIGFKLGVRPSQG--GEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDA 1164
P P + L +P A + T S+ + YT+ +
Sbjct: 19715 GRPVPNV---LWSKPDTDLRTRAYVDTTDSRTSLTIENANRNDSGKYTLTIQNVLSAASL 19771
Query: 1165 PIVNKVVTPLSPPTNLHLE-ANPDTGVLTVSW---ERSTTPDITGYRITTTPTNGQQGNS 1220
+V KV+ PPTN+ ++ ++ VL SW E + Y I + + S
Sbjct: 19772 TLVVKVLDTPGPPTNITVQDVTKESAVL--SWDVPENDGGAPVKNYHIEKREASKKAWVS 19829
Query: 1221 LE--------EVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPEVPQLTD 1272
+ +V + + + + +S E+ V + + KE V I++ P P+
Sbjct: 19830 VTNNCNRLSYKVTNLQEGAIYYFRVSGENEFGVGIPA--ETKEGVKITEK--PSPPE--K 19883
Query: 1273 LSFVDITDSSIGLRWTPLN---SSTIIGYRITVVAAGEGIPIFEDFVDSSVG---YYTVT 1326
L I+ S+ L W S I+ Y + + G+ +++V +V ++ V+
Sbjct: 19884 LGVTSISKDSVSLTWLKPEHDGGSRIVHYVVEALEKGQ-----KNWVKCAVAKSTHHVVS 19938
Query: 1327 GLEPGIDYDISVITLINGGESAPT-----TLTQQTAVPPPTDLRFTNIGPDTMRVTWAPP 1381
GL +Y V G S P L ++ PP D++ N T+ V
Sbjct: 19939 GLRENSEYFFRVFAENQAGLSDPRELLLPVLIKEQLEPPEIDMK--NFPSHTVYVRAGSN 19996
Query: 1382 PSIDLTNFLVRYSPVKNEEDVAELSISPSDNA-VVLTNLLPGTEYVVSVSSVYEQHESTP 1440
+D+ V D L + N + NL + V+ + + +
Sbjct: 19997 LKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADAGRYEITAAN 20056
Query: 1441 LRGRQKTGLD--------SPTG-IDFSDITANSFTVHWIAPR----ATITGYRIRHHPEH 1487
G K ++ PTG + SDIT S T+ W P+ + +T Y + E
Sbjct: 20057 SSGTTKAFINIVVLDRPGPPTGPVVISDITEESVTLKWEPPKYDGGSQVTNYILLKR-ET 20115
Query: 1488 FSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGR------EESPLLIGQQSTVSDV 1541
+ E +R + + LT G EY I A N + + + + T
Sbjct: 20116 STAVWTEVSATVARTMMKVMKLTTGEEYQFRIKAENRFGISDHIDSACVTVKLPYTTPGP 20175
Query: 1542 PRDLEVVAATPTSLLISWDAPAVT----VRYYRITYGETGGNSPVQEFTVPGSKSTATIS 1597
P V T S+ + W P V Y + + + + + ++
Sbjct: 20176 PSTPWVTNVTRESITVGWHEPVSNGGSAVVGYHLEMKDRNSILWQKANKLVIRTTHFKVT 20235
Query: 1598 GLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKW---- 1653
+ G+ Y VYA G S + + P +++TD+ NS+S+ W
Sbjct: 20236 TISAGLIYEFRVYAENAAGVGKPSHPSEPVLAIDACEPPRNVRITDISKNSVSLSWQQPA 20295
Query: 1654 LPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE-S 1712
S +TGY V TK +T+ I GL +Y V+A+N G S
Sbjct: 20296 FDGGSKITGYIVERRDLPDGRWTKASFTNVTETQFIISGLTQNSQYEFRVFARNAVGSIS 20355
Query: 1713 QPL-VQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAP 1771
P V +T ID G D+ ++ ++ + G + R S E +
Sbjct: 20356 NPSEVVGPITCIDSYGGPVI-DLPLEYTEVV-KYRAGTSVKLRAGISGKPAPTIEWYK-D 20412
Query: 1772 DGEEDTAELQGLRPGSEYTVSVVALHDDMES-------QPLIGTQSTAI---------PA 1815
D E T L + ++ ++ D + S + +G+ S I P
Sbjct: 20413 DKELQTNALVCVENTTDLASILIKDADRLNSGCYELKLRNAMGSASATIRVQILDKPGPP 20472
Query: 1816 PTDLKFTQVTPTSLSAQWTPP----NVQLTGYRVRVTPKEKTGPM--KEINLAPDSSSVV 1869
++F VT ++ W PP ++T Y + K +T + ++ + +
Sbjct: 20473 GGPIEFKTVTAEKITLLWRPPADDGGAKITHY---IVEKRETSRVVWSMVSEHLEECIIT 20529
Query: 1870 VSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENV----SPPRRARVTDATETTITISW 1925
+ ++ +Y V A+ P + +N PP VT T+ ++T+ W
Sbjct: 20530 TTKIIKGNEYIFRVRAVNKYGIGEPLESDSVVAKNAFVTPGPPGIPEVTKITKNSMTVVW 20589
Query: 1926 RTKT----ETITGFQV---DAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLN 1978
I+G+ + D ++ TI+ D R +TGL +DY+ + +N
Sbjct: 20590 SRPIADGGSDISGYFLEKRDKKSLGWFKVLKETIR-DTRQ-KVTGLTENSDYQYRVCAVN 20647
Query: 1979 DNAR---SSPVVI-DASTAIDAP---SNLRFLATTPNSLLVSWQPP----RARITGYIIK 2027
+ S P A+ ID P + +R +T +S+ + W P + +TGY+++
Sbjct: 20648 AAGQGPFSEPSEFYKAADPIDPPGPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVVE 20707
Query: 2028 YEKPGSPPREVVP-RPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPL 2076
+ V + TE ++ L+PG Y V A+ + EP+
Sbjct: 20708 IRQGEEEEWTTVSTKGEVRTTEYVVSNLKPGVNYYFRVSAVNCAGQGEPI 20757
Score = 114 bits (286), Expect = 9e-25
Identities = 308/1475 (20%), Positives = 520/1475 (35%), Gaps = 204/1475 (13%)
Query: 806 SQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ----APITGYRIVYSPSVEGS-STELNLPE 860
S+ P P + T+ V+ + + W P+ A IT Y I T + +
Sbjct: 6689 SKYDVPGPPLNVTITDVNRFGVSLTWEPPEYDGGAEITNYVIELRDKTSIRWDTAMTVRA 6748
Query: 861 TANSVTLSDLQPGVQYNITIYA-----VEENQESTPVVIQQETTGTPRSDTVPSPRDLQF 915
S T++D+ G +Y+ + A V + +TP V + P P +L
Sbjct: 6749 EDLSATVTDVVEGQEYSFRVRAQNRIGVGKPSAATPFVKVADPIERPSP-----PVNLTS 6803
Query: 916 VEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGV 971
+ T V + W PP S + GY ++ + + +VTGL G
Sbjct: 6804 SDQTQSSVQLKWEPPLKDGGSPILGYIIERCEEGKDNWIRCNMKLVPELTYKVTGLEKGN 6863
Query: 972 TYYFKVFAVSHGRESKP------LTA-----QQTTKLDA-PTNLQFVNETDSTVLVRWTP 1019
Y ++V A + S P LTA + T L A L+ + T+LV T
Sbjct: 6864 KYLYRVSAENKAGVSDPSEILGPLTADDAFVEPTMDLSAFKDGLEVIVPNPITILVPSTG 6923
Query: 1020 -PRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKA 1078
PR T L + + ++S Y + P+ + +K
Sbjct: 6924 YPRPTATWCFGDKVLETGDRVKM----KTLSAYAELVISPSERSDKGIYTLKLENRVKTI 6979
Query: 1079 TG---VFTTLQPGSSIPPYNTEVTETTIVITWTP------APRIGFKLGVRPSQGGEAPR 1129
+G V +P + ++T+ ++ +TW P +P G+ + R E R
Sbjct: 6980 SGEIDVNVIARPSAPKELKFGDITKDSVHLTWEPPDDDGGSPLTGYVVEKR-----EVSR 7034
Query: 1130 EVTSDSGSIV------VSGLTPGVEYVYTIQVLRDGQERDAPIVNKVV---TPLS---PP 1177
+ + V V L G EY++ + + V++ V TP + PP
Sbjct: 7035 KTWTKVMDFVTDLEFTVPDLVQGKEYLFKVCARNKCGPGEPAYVDEPVNMSTPATVPDPP 7094
Query: 1178 TNLHLEANPDTGVLTVSWERSTTPD---ITGYRITTTPTNGQQGNSLEEVVHADQSSCTF 1234
N+ + ++W+ I GY + P + + E V + T
Sbjct: 7095 ENVKWRDRTANSIF-LTWDPPKNDGGSRIKGYIVERCPRGSDKWVACGEPVAETKMEVT- 7152
Query: 1235 DNLSPGLEYNVSVYTVKDDKESVPISDT-------------IIPEVPQLTDLSF-----V 1276
L G Y V + S P T I +V L L+ +
Sbjct: 7153 -GLEEGKWYAYRVKALNRQGASKPSRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKI 7211
Query: 1277 DITDSSIG-----LRWTPLNSSTIIGYRITVVAAGEGIP-----IFEDFVDSSVGYYTVT 1326
++ + G + WT + RIT+ E +P D S G Y +
Sbjct: 7212 ELPATVTGKPEPKITWTKADMILKQDKRITI----ENVPKKSTVTIVDSKRSDTGTYIIE 7267
Query: 1327 GLEPGIDYDISVITLINGGESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAPPPS--- 1383
+ + G +A + PP T++ ++ +TW PP
Sbjct: 7268 AVN------------VCGRATAVVEVNVLDKPGPPAAFDITDVTNESCLLTWNPPRDDGG 7315
Query: 1384 IDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSS-----VYEQHES 1438
+TN++V +E +LS + D T L+P EY+ V++ V E ++
Sbjct: 7316 SKITNYVVERRATDSEV-WHKLSSTVKDTNFKATKLIPNKEYIFRVAAENMYGVGEPVQA 7374
Query: 1439 TPLRGR-QKTGLDSPTGIDFSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPR 1493
+P+ + Q PT ++ SDIT ++ T+ W P + ITGY + R
Sbjct: 7375 SPITAKYQFDPPGPPTRLEPSDITKDAVTLTWCEPDDDGGSPITGYWVERLDPDTDKWVR 7434
Query: 1494 EDRVPHSRNSITLTNLTPGTEYVVSIVALN-------GREESPLLIGQQSTVSDVPRDLE 1546
+++P + + LT +Y ++A N + P+LI P
Sbjct: 7435 CNKMPVKDTTYRVKGLTNKKKYRFRVLAENLAGPGKPSKSTEPILIKDPIDPPWPPGKPT 7494
Query: 1547 VVAATPTSLLISWDAP----AVTVRYYRITYGETGGNSPVQEFTVPGSKSTA-TISGLKP 1601
V TS+ ++W P + Y I +TG + V+ G +T + GL
Sbjct: 7495 VKDVGKTSVRLNWTKPEHDGGAKIESYVIEMLKTGTDEWVR--VAEGVPTTQHLLPGLME 7552
Query: 1602 GVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQ---MQVTDVQDNSISVKWL---- 1654
G +Y+ V AV G+S S + R ++ PS ++V ++ N+ +KW
Sbjct: 7553 GQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLEVINITKNTADLKWTVPEK 7612
Query: 1655 PSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQ- 1713
SP+T Y V G T D T+ T+ L YV V A+N G+S
Sbjct: 7613 DGGSPITNYIVEKRDVRRKGWQTVDTTVKD-TKCTVTPLTEGSLYVFRVAAENAIGQSDY 7671
Query: 1714 ------PLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQ----VSRYRVTYSSPEDG 1763
L + T P LA DV + + WE P+ + RY +
Sbjct: 7672 TEIEDSVLAKDTFTTPGPPYALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKERLGT 7731
Query: 1764 IHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPT------ 1817
G + + + G+E V A ++ P T+ +I PT
Sbjct: 7732 RWVKAGKTAGPDCNFRVTDVIEGTEVQFQVRAENEAGVGHPSEPTEILSIEDPTSPPSPP 7791
Query: 1818 -DLKFTQVTPTSLSAQWTPPNVQ----LTGYRVRVTPKEKTGPMKEINLAP--DSSSVVV 1870
DL T ++ W PP + GY V + P T +N P D V
Sbjct: 7792 LDLHVTDAGRKHIAIAWKPPEKNGGSPIIGYHVEMCP-VGTEKWMRVNSRPIKDLKFKVE 7850
Query: 1871 SGLMVATKYEVSVYALKDTLTSRP---AQGVVTTLENVSP-----PRRARVTDATETTIT 1922
G++ +Y + V A+ S P ++ VV + P V + + +I
Sbjct: 7851 EGVVPDKEYVLRVRAVNAIGVSEPSEISENVVAKDPDCKPTIDLETHDIIVIEGEKLSIP 7910
Query: 1923 ISWRTKTETITGFQVDAVPANGQTPIQRTIKPD-VRSYTITGLQPGTDYKIYLYTLNDNA 1981
+ +R + D + T+K D + ++ D IY TL +
Sbjct: 7911 VPFRAVPVPTVSWHKDGKEVKASDRL--TMKNDHISAHLEVPKSVRADAGIYTITLENKL 7968
Query: 1982 RSSPVVIDAST-AIDAP-SNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPP 2035
S+ I+ + P +++ T +S ++W+PP I Y+++ + G
Sbjct: 7969 GSATASINVKVIGLPGPCKDIKASDITKSSCKLTWEPPEFDGGTPILHYVLERREAGR-- 8026
Query: 2036 REVVP-RPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELPQLVTLPHP 2094
R +P T+ L P EY V A+ +G + EL V P
Sbjct: 8027 RTYIPVMSGENKLSWTVKDLIPNGEYFFRVKAVNK-------VGGGEYIELKNPVIAQDP 8079
Query: 2095 NLHGPEILDV----PSTVQKTPFVTHPGYDTGNGI 2125
+DV P+ T P YD G+ I
Sbjct: 8080 KQPPDPPVDVEVHNPTAEAMTITWKPPLYDGGSKI 8114
Score = 114 bits (286), Expect = 9e-25
Identities = 280/1356 (20%), Positives = 495/1356 (36%), Gaps = 217/1356 (16%)
Query: 727 SVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQ--YLDLPSTA--TSVNIPDLLP 782
+VTE+T+ V+SW D G ++++ + ++ + + + ++ S T + + LL
Sbjct: 15066 AVTEVTSEKCVLSWFPPLDD-GGAKIDHYIVQKRETSRLAWTNVASEVQVTKLKVTKLLK 15124
Query: 783 GRKYI-----VNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAP 837
G +YI VN Y + E E +L+ + PD P +P V + S+VV W P +
Sbjct: 15125 GNEYIFRVMAVNKYGVGEPLESEPVLAVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDS- 15183
Query: 838 ITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQ-------PGVQYNITIYAVEENQEST 890
G + + VE N TL+DL+ G +Y I A S
Sbjct: 15184 -DGGSEIINYIVERRDKAGQRWIKCNKKTLTDLRYKVSGLTEGHEYEFRIMAENAAGISA 15242
Query: 891 PVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNL 946
P P + + ++ + ++I W P S +TGY V++ L
Sbjct: 15243 PSPTSPFYKACDTVFKPGPPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIA---L 15299
Query: 947 PGEHGQRLPIS----RNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLD---A 999
P E ++ + T +TGL+ Y +++A++ +P T K +
Sbjct: 15300 PEEDEWQIVTPPAGLKATSYTITGLTENQEYKIRIYAMNSEGLGEPALVPGTPKAEDRML 15359
Query: 1000 PTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPR---QYNVGPSVSKYPLRNL 1056
P ++ + V +R RL V + R P + G S+ K ++
Sbjct: 15360 PPEIELDADLRKVVTIR------ACCTLRLFVPIKGRPAPEVKWARDHGESLDK---ASI 15410
Query: 1057 QPASEYTVSLVAIKGNQESPK----------ATGVFTTLQ----PGSSIPPYNTEVTETT 1102
+ S YT+ +V +S K + F ++ PG EVT+T+
Sbjct: 15411 ESTSSYTLLIVGNVNRFDSGKYILTVENSSGSKSAFVNVRVLDTPGPPQDLKVKEVTKTS 15470
Query: 1103 IVITWTPAPRI--GFKLGVRPSQGGEAPREVTS------DSGSIVVSGLTPGVEYVYTIQ 1154
+ +TW P P + G K+ + E+ R+ S S V L G Y + +
Sbjct: 15471 VTLTWDP-PLLDGGSKIKNYIVEKRESTRKAYSTVATNCHKTSWKVDQLQEGCSYYF--R 15527
Query: 1155 VLRDGQ------ERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPD---ITG 1205
VL + + A V PL P ++ ++ +++SWE+ I G
Sbjct: 15528 VLAENEYGIGLPAETAESVKASERPLPPGKITLMDVTRNS--VSLSWEKPEHDGGSRILG 15585
Query: 1206 YRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYT-----VKDDKE-SVPI 1259
Y I T G + V +++ T L G EY+ V + D ++ SVP+
Sbjct: 15586 Y-IVEMQTKGSDKWATCATVKVTEATIT--GLIQGEEYSFRVSAQNEKGISDPRQLSVPV 15642
Query: 1260 --SDTIIPEVPQLTDLSFVDITDSSI------------GLRW----TPLNSSTIIGYRIT 1301
D +IP +L +F + + + W PL +T + T
Sbjct: 15643 IAKDLVIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAEST 15702
Query: 1302 VVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTL---TQQTAV 1358
+ +D VG+Y V+ L N A TL
Sbjct: 15703 ---ENNSLLTIKDACREDVGHY--------------VVKLTNSAGEAIETLNVIVLDKPG 15745
Query: 1359 PPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAE---LSISPSDNAVV 1415
PP ++ + D++ ++W PP D + + Y K + +S + + +
Sbjct: 15746 PPTGPVKMDEVTADSITLSWG-PPKYDGGSSINNYIVEKRDTSTTTWQIVSATVARTTIK 15804
Query: 1416 LTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTG-----LDSPTGIDFSDITA-NSFTVHW 1469
L G EY +++ +ST L + P G +++ +S V W
Sbjct: 15805 ACRLKTGCEYQFRIAAENRYGKSTYLNSEPTVAQYPFKVPGPPGTPVVTLSSRDSMEVQW 15864
Query: 1470 IAP----RATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGR 1525
P + + GY + + + ++ P + T L G EY + A
Sbjct: 15865 NEPISDGGSRVIGYHLERKERNSILWVKLNKTPIPQTKFKTTGLEEGVEYEFRVSA---- 15920
Query: 1526 EESPLLIGQQSTVSD--VPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQ 1583
E+ + IG+ S VS+ V RD P +++++ + +VT+++ + TY G S +
Sbjct: 15921 -ENIVGIGKPSKVSECYVARDPCDPPGRPEAIIVTRN--SVTLQWKKPTY---DGGSKIT 15974
Query: 1584 EFTVPGS--------KSTAT--------ISGLKPGVDYTITVYAVTGRG-DSPASSKPIS 1626
+ V K++ T ++GL Y V A G S S +
Sbjct: 15975 GYIVEKKELPEGRWMKASFTNIIDTHFEVTGLVEDHRYEFRVIARNAAGVFSEPSESTGA 16034
Query: 1627 INYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQT 1686
I R E+D P +D + ++V P PT G +
Sbjct: 16035 ITARDEVDPPRISMDPKYKDTIV-------VHAGESFKVDADIYGKPIPTIQWIKGDQEL 16087
Query: 1687 EMTIEGLQPTVEYVVS---------------VYAQNPSGESQPLVQTAVTNIDRP----K 1727
T + ++ S + A+N +GE V V +DRP
Sbjct: 16088 SNTARLEIKSTDFATSLSVKDAVRVDSGNYILKAKNVAGERSVTVNVKV--LDRPGPPEG 16145
Query: 1728 GLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHEL-FPAPDGEEDT--AELQGLR 1784
+ + V + +AW+ P + Y L + D T ++ L
Sbjct: 16146 PVVISGVTAEKCTLAWKPPLQDGGSDIINYIVERRETSRLVWTVVDANVQTLSCKVTKLL 16205
Query: 1785 PGSEYTVSVVALH-----DDMESQPLIGTQSTAIP-APTDLKFTQVTPTSLSAQWTPP-- 1836
G+EYT ++A++ + +ES+P++ +P AP + T VT S+ W P
Sbjct: 16206 EGNEYTFRIMAVNKYGVGEPLESEPVVAKNPFVVPDAPKAPEVTTVTKDSMIVVWERPAS 16265
Query: 1837 --NVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRP 1894
++ GY + KE + + V+GL+ YE V A S P
Sbjct: 16266 DGGSEILGYVLEKRDKEGIRWTRCHKRLIGELRLRVTGLIENHDYEFRVSAENAAGLSEP 16325
Query: 1895 A-----QGVVTTLENVSPPRRARVTDATETTITISW 1925
+ Q + PP +V D T +++ +SW
Sbjct: 16326 SPPSAYQKACDPIYKPGPPNNPKVIDITRSSVFLSW 16361
Score = 114 bits (284), Expect = 2e-24
Identities = 358/1658 (21%), Positives = 597/1658 (36%), Gaps = 251/1658 (15%)
Query: 607 SSSGPVEVFIT----ETPSQPNSHPIQWNAPQPSHISKYILRWRP---------KNSVGR 653
+SSG F+T +TP P + ++ + L W P KN V
Sbjct: 17602 NSSGSKSAFVTVKVLDTPGPPQNLAVKEVRKDSA-----FLVWEPPIIDGGAKVKNYVID 17656
Query: 654 WKEATIPGHLN--------SYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTP 705
+E+T + N S+ ++ L G +Y ++++ ++G P
Sbjct: 17657 KRESTRKAYANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFG-------------VGVP 17703
Query: 706 VTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVS----ASDTVSGFRVEYELSEEGD 761
V + P SP ++T+++ +S + W V G+ VE + +G
Sbjct: 17704 VETVDAVKAAEPPSP--PGKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVE--MQPKGT 17759
Query: 762 EPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQ 821
E + S + + L G++Y V +E G+ + A D P++
Sbjct: 17760 EKWSIVAESKVCNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKL 17819
Query: 822 VDDTSIVVRWS--RPQAPITGY-RIVYSPSVEGS----STELNLPETANSVTLSDLQPGV 874
+T + + + P+ G R S +G +T +N+ ETA S L ++ G
Sbjct: 17820 PFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLH-IKEGN 17878
Query: 875 QYNITIYAVEENQESTPV-----VIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTP 929
+ + Y V + VI E G P ++F EV+ V I W P
Sbjct: 17879 KDDFGKYTVTATNSAGTATENLSVIVLEKPGPPVGP-------VRFDEVSADFVVISWEP 17931
Query: 930 PESA----VTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRE 985
P ++ Y V+ H ++R T ++T L G Y F++FA + +
Sbjct: 17932 PAYTGGCQISNYIVEKRDTTTTTWHMVSATVARTTI-KITKLKTGTEYQFRIFAENRYGK 17990
Query: 986 SKPLTA-----QQTTKLDAPTNLQFVNE-TDSTVLVRWTPP----RAQITGYRLTVGLTR 1035
S PL + Q K P FV + +LV+W P +I GY L
Sbjct: 17991 SAPLDSKAVIVQYPFKEPGPPGTPFVTSISKDQMLVQWHEPVNDGGTKIIGYHLEQKEKN 18050
Query: 1036 RGQPRQYNVGP-SVSKYPLRNLQPASEY--TVSLVAIKGNQESPKATGVFTTLQPGSSIP 1092
+ N P +K+ L EY VS I G + K + F P P
Sbjct: 18051 SILWVKLNKTPIQDTKFKTTGLDEGLEYEFKVSAENIVGIGKPSKVSECFVARDPCD--P 18108
Query: 1093 PYNTE---VTETTIVITW-TPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVE 1148
P E +T + + W PA G K+ G + G + + T +E
Sbjct: 18109 PGRPEAIVITRNNVTLKWKKPAYDGGSKI------TGYIVEKKDLPDGRWMKASFTNVLE 18162
Query: 1149 YVYTIQVLRDGQERDAPIV-NKVVTPLSPPT---------------NLHLEAN-PDTGVL 1191
+T+ L + Q + ++ S P+ N L+ D V+
Sbjct: 18163 TEFTVSGLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARDEIDAPNASLDPKYKDVIVV 18222
Query: 1192 TVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNL---------SPGLE 1242
DI G I + + G LEE + T + G +
Sbjct: 18223 HAGETFVLEADIRGKPIPDVVWS-KDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQ 18281
Query: 1243 YNVSVYTVKDDKESVPISDTIIPEV-PQLTDLSFVDITDSSIGLRWTP--LNSSTIIGYR 1299
Y + + V K S+PI+ ++ P L +T L W P + I +
Sbjct: 18282 YILKLSNVGGTK-SIPITVKVLDRPGPPEGPLKVTGVTAEKCYLAWNPPLQDGGANISHY 18340
Query: 1300 ITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGG-----ESAPTTLTQ 1354
I + + + Y VT L PG +Y V+ + G ES P T
Sbjct: 18341 IIEKRETSRLSWTQVSTEVQALNYKVTKLLPGNEYIFRVMAVNKYGIGEPLESGPVTACN 18400
Query: 1355 QTAVP-PPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISP---S 1410
P PP+ + I D+M VTWA P T +++E V + +
Sbjct: 18401 PYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDKEGVRWTKCNKKTLT 18460
Query: 1411 DNAVVLTNLLPGTEYVVSVSS-----VYEQHESTPLRGRQKTGL---DSPTGIDFSDITA 1462
D + +T L G Y V++ V E E + R L P+ +D +
Sbjct: 18461 DLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFY-RACDALYPPGPPSNPKVTDTSR 18519
Query: 1463 NSFTVHWIAP----RATITGYRIRHHPEHFSGRPREDRVPHS---RNSITLTNLTPGTEY 1515
+S ++ W P A + GY + + + P + T+T L TEY
Sbjct: 18520 SSVSLAWSKPIYDGGAPVKGYVV--EVKEAAADEWTTCTPPTGLQGKQFTVTKLKENTEY 18577
Query: 1516 VVSIVALN--GREESPLLIGQQSTVSDV-PRDLEVVAATPTSLLISWDAPAVTVRYYRIT 1572
I A+N G E L G + P ++E+ A +++ A T+R +
Sbjct: 18578 NFRICAINSEGVGEPATLPGSVVAQERIEPPEIELDADLRKVVVLRASA---TLRLFVTI 18634
Query: 1573 YGETGGNSPVQEFTVPGSKSTAT-ISGLKPGVDYTITVYAVTGRGDS---------PASS 1622
G P E ++ T + ++ +T+ V R DS + S
Sbjct: 18635 KGR-----PEPEVKWEKAEGILTDRAQIEVTSSFTMLVIDNVTRFDSGRYNLTLENNSGS 18689
Query: 1623 KPISINYRTEIDKPS---QMQVTDVQDNSISVKWLP----SSSPVTGYRV---TTTPKNG 1672
K +N R +D PS + + +V+ +S+++ W P + +T Y V TT K
Sbjct: 18690 KTAFVNVRV-LDSPSAPVNLTIREVKKDSVTLSWEPPLIDGGAKITNYIVEKRETTRK-- 18746
Query: 1673 PGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPK----G 1728
T T +T IE LQ Y V A N G P T + P
Sbjct: 18747 --AYATITNNCTKTTFRIENLQEGCSYYFRVLASNEYGIGLPAETTEPVKVSEPPLPPGR 18804
Query: 1729 LAFTDVDVDSIKIAWESPQ----GQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLR 1784
+ DV ++ I WE P+ +++ Y V + G + + A + GL
Sbjct: 18805 VTLVDVTRNTATIKWEKPESDGGSKITGYVVEMQT--KGSEKWSTCTQVKTLEATISGLT 18862
Query: 1785 PGSEYTVSVVALHDDMESQPL-----IGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQ 1839
G EY V A+++ S P + + I +L F T + + +V
Sbjct: 18863 AGEEYVFRVAAVNEKGRSDPRQLGVPVIARDIEIKPSVELPFH--TFNVKAREQLKIDVP 18920
Query: 1840 LTGYRVRVTPKEKTG-PMKEINLAPDSSSVVVSGLMV--ATKYEVSVYAL--KDTLTSRP 1894
G K G +KE SSS V+ L + A+K +V Y L ++ S
Sbjct: 18921 FKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSNSAGSIT 18980
Query: 1895 AQGVVTTLENVSPPRRARVTDATETTITISWRTKTE----TITGFQVDAVPANGQT---- 1946
+ L+ PP R+ + + +ITISW I+ + V+ T
Sbjct: 18981 VPITIIVLDRPGPPGPIRIDEVSCDSITISWNPPEYDGGCQISNYIVEKKETTSTTWHIV 19040
Query: 1947 --PIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDA-------- 1996
+ RT S I L G++Y+ + N +SS S+A+ A
Sbjct: 19041 SQAVART------SIKIVRLTTGSEYQFRVCAENRYGKSS---YSESSAVVAEYPFSPPG 19091
Query: 1997 -PSNLRFLATTPNSLLVSWQPP----RARITGYIIKYEKPGSPPREVVPRPRPGVTEATI 2051
P + + T +++LV+WQ P +R+ GY ++Y++ S + T+ +
Sbjct: 19092 PPGTPKVVHATKSTMLVTWQVPVNDGGSRVIGYHLEYKERSSILWSKANKILIADTQMKV 19151
Query: 2052 TGLEPGT--EYTIYVIAL----KNNQKSEPLIGRKKTD 2083
+GL+ G EY +Y + K ++ EP+ R D
Sbjct: 19152 SGLDEGLMYEYRVYAENIAGIGKCSKSCEPVPARDPCD 19189
Score = 111 bits (278), Expect = 8e-24
Identities = 306/1510 (20%), Positives = 522/1510 (34%), Gaps = 241/1510 (15%)
Query: 758 EEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLI---LSTSQTTAPDAP 814
E GD + L + A V + P + +Y + + I + + P AP
Sbjct: 6939 ETGDRVKMKTLSAYAELV----ISPSERSDKGIYTLKLENRVKTISGEIDVNVIARPSAP 6994
Query: 815 PDPTVDQVDDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTLSDL 870
+ + S+ + W P +P+TGY + + T++ T T+ DL
Sbjct: 6995 KELKFGDITKDSVHLTWEPPDDDGGSPLTGYVVEKREVSRKTWTKVMDFVTDLEFTVPDL 7054
Query: 871 QPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP 930
G +Y + A + P + + + + P ++++ + T + + W PP
Sbjct: 7055 VQGKEYLFKVCARNKCGPGEPAYVDEPVNMSTPATVPDPPENVKWRDRTANSIFLTWDPP 7114
Query: 931 E----SAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRES 986
+ S + GY V+ P P++ T EVTGL G Y ++V A++ S
Sbjct: 7115 KNDGGSRIKGYIVERCPRGSDKWVACGEPVA-ETKMEVTGLEEGKWYAYRVKALNRQGAS 7173
Query: 987 KP---------------------------LTAQQTTKLDAPTNLQFVNETDSTVLVRWTP 1019
KP LT + TK++ P + E T WT
Sbjct: 7174 KPSRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKIT----WT- 7228
Query: 1020 PRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKAT 1079
+A + + +T P++ V SK Y + V + G +
Sbjct: 7229 -KADMI-LKQDKRITIENVPKKSTVTIVDSK-----RSDTGTYIIEAVNVCGRATAVVEV 7281
Query: 1080 GVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRI--GFKLGVRPSQGGEAPREVTSDSGS 1137
V +PG T+VT + ++TW P PR G K+ + EV S
Sbjct: 7282 NVLD--KPGPPAAFDITDVTNESCLLTWNP-PRDDGGSKITNYVVERRATDSEVWHKLSS 7338
Query: 1138 IV------VSGLTPGVEYVYTI---QVLRDGQERDA-PIVNKV-VTPLSPPTNLHLEANP 1186
V + L P EY++ + + G+ A PI K P PPT L ++
Sbjct: 7339 TVKDTNFKATKLIPNKEYIFRVAAENMYGVGEPVQASPITAKYQFDPPGPPTRLE-PSDI 7397
Query: 1187 DTGVLTVSW---ERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEY 1243
+T++W + ITGY + + + ++ D ++ L+ +Y
Sbjct: 7398 TKDAVTLTWCEPDDDGGSPITGYWVERLDPDTDKWVRCNKMPVKD-TTYRVKGLTNKKKY 7456
Query: 1244 NVSVYTV------KDDKESVP--ISDTIIPEVPQLTDLSFVDITDSSIGLRWTPL---NS 1292
V K K + P I D I P P + D+ +S+ L WT
Sbjct: 7457 RFRVLAENLAGPGKPSKSTEPILIKDPIDPPWPP-GKPTVKDVGKTSVRLNWTKPEHDGG 7515
Query: 1293 STIIGYRITVVAAG--------EGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLING 1344
+ I Y I ++ G EG+P + + + GL G +Y V +
Sbjct: 7516 AKIESYVIEMLKTGTDEWVRVAEGVPTTQ---------HLLPGLMEGQEYSFRVRAVNKA 7566
Query: 1345 GESAPT-----TLTQQTAVP--PPTDLRFTNIGPDTMRVTWAPPP---SIDLTNFLVRYS 1394
GES P+ L ++ P PP L NI +T + W P +TN++V
Sbjct: 7567 GESEPSEPSDPVLCREKLYPPSPPRWLEVINITKNTADLKWTVPEKDGGSPITNYIVEKR 7626
Query: 1395 PVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVS-------SVYEQHESTPLRGRQKT 1447
V+ + + + D +T L G+ YV V+ S Y + E + L T
Sbjct: 7627 DVR-RKGWQTVDTTVKDTKCTVTPLTEGSLYVFRVAAENAIGQSDYTEIEDSVLAKDTFT 7685
Query: 1448 GLDSPTGIDFSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRNS 1503
P + D+T + W P+ I Y I + + + +
Sbjct: 7686 TPGPPYALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKERLGTRWVKAGKTAGPDCN 7745
Query: 1504 ITLTNLTPGTEYVVSIVALN----GREESP---LLIGQQSTVSDVPRDLEVVAATPTSLL 1556
+T++ GTE + A N G P L I ++ P DL V A +
Sbjct: 7746 FRVTDVIEGTEVQFQVRAENEAGVGHPSEPTEILSIEDPTSPPSPPLDLHVTDAGRKHIA 7805
Query: 1557 ISWDAPAVTVRYYRITYGETGGNSPVQEFTVP----GSKSTATIS-------------GL 1599
I+W P E G SP+ + V G++ ++ G+
Sbjct: 7806 IAWKPP------------EKNGGSPIIGYHVEMCPVGTEKWMRVNSRPIKDLKFKVEEGV 7853
Query: 1600 KPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSP 1659
P +Y + V AV G S+P I+ P D++ + I V S
Sbjct: 7854 VPDKEYVLRVRAVNAIG----VSEPSEISENVVAKDPDCKPTIDLETHDIIVIEGEKLSI 7909
Query: 1660 VTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYA---------QNPSG 1710
+R P + D+ M + + +E SV A +N G
Sbjct: 7910 PVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLG 7969
Query: 1711 ESQPLVQTAVTNIDRP-KGLAFTDVDVDSIKIAWESPQ--GQVSRYRVTYSSPEDGIHEL 1767
+ + V + P K + +D+ S K+ WE P+ G E G
Sbjct: 7970 SATASINVKVIGLPGPCKDIKASDITKSSCKLTWEPPEFDGGTPILHYVLERREAGRRTY 8029
Query: 1768 FPAPDGEEDTA-ELQGLRPGSEYTVSVVALH-----DDME-SQPLIGTQSTAIP-APTDL 1819
P GE + ++ L P EY V A++ + +E P+I P P D+
Sbjct: 8030 IPVMSGENKLSWTVKDLIPNGEYFFRVKAVNKVGGGEYIELKNPVIAQDPKQPPDPPVDV 8089
Query: 1820 KFTQVTPTSLSAQWTPP----NVQLTGYRV-RVTPKEKTGPMKEINLAPDSSSVVVSGLM 1874
+ T +++ W PP ++ GY + ++ E+ +L P + GL
Sbjct: 8090 EVHNPTAEAMTITWKPPLYDGGSKIMGYIIEKIAKGEERWKRCNEHLVP-ILTYTAKGLE 8148
Query: 1875 VATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTI------------- 1921
+Y+ V A S P++ T + V P +V T +
Sbjct: 8149 EGKEYQFRVRAENAAGISEPSRATPPT-KAVDPIDAPKVILRTSLEVKRGDEIALDASIS 8207
Query: 1922 -----TISWRTKTETITGFQVD--------------------AVPANGQTPIQRTIKPDV 1956
TI+W I ++ +P + I + K +
Sbjct: 8208 GSPYPTITWIKDENVIVPEEIKKRAAPLVRRRKGEVQEEEPFVLPLTQRLSIDNSKKGES 8267
Query: 1957 RSYTITGLQPGTDYKIYLYTL-NDNA-RSSPVVIDASTAIDAPSNLRFLATTPNSLLVSW 2014
+ L+P D+ +Y+ + ND+ +P + P N F S+L W
Sbjct: 8268 QLRVRDSLRP--DHGLYMIKVENDHGIAKAPCTVSVLDTPGPPINFVFEDIRKTSVLCKW 8325
Query: 2015 QPP----RARITGYIIKYEKPGSPPRE-VVPRPRPGVTEATITGLEPGTEYTIYVIALKN 2069
+PP + I Y ++ + P E +V + ++T L G EY V A
Sbjct: 8326 EPPLDDGGSEIINYTLEKKDKTKPDSEWIVVTSTLRHCKYSVTKLIEGKEYLFRVRAENR 8385
Query: 2070 NQKSEPLIGR 2079
P + +
Sbjct: 8386 FGPGPPCVSK 8395
Score = 109 bits (273), Expect = 3e-23
Identities = 290/1404 (20%), Positives = 524/1404 (37%), Gaps = 190/1404 (13%)
Query: 812 DAPPDPT----VDQVDDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETAN 863
D P PT + + + S+ ++W P+ + +T Y ++ + TE++
Sbjct: 20071 DRPGPPTGPVVISDITEESVTLKWEPPKYDGGSQVTNYILLKRETSTAVWTEVSATVART 20130
Query: 864 SVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFV-EVTDVK 922
+ + L G +Y I A EN+ I T P P +V VT
Sbjct: 20131 MMKVMKLTTGEEYQFRIKA--ENRFGISDHIDSACVTVKLPYTTPGPPSTPWVTNVTRES 20188
Query: 923 VTIMWTPPES----AVTGYRVDVIPVN-LPGEHGQRLPISRNTFAEVTGLSPGVTYYFKV 977
+T+ W P S AV GY +++ N + + +L I R T +VT +S G+ Y F+V
Sbjct: 20189 ITVGWHEPVSNGGSAVVGYHLEMKDRNSILWQKANKLVI-RTTHFKVTTISAGLIYEFRV 20247
Query: 978 FAVSHGRESKPL-TAQQTTKLDA---PTNLQFVNETDSTVLVRWTPPR----AQITGYRL 1029
+A + KP ++ +DA P N++ + + ++V + W P ++ITGY
Sbjct: 20248 YAENAAGVGKPSHPSEPVLAIDACEPPRNVRITDISKNSVSLSWQQPAFDGGSKITGYI- 20306
Query: 1030 TVGLTRRGQP-----RQYNVGPSVSKYPLRNLQPASEYTVSLVA--IKGNQESP-KATGV 1081
+ RR P + + +++ + L S+Y + A G+ +P + G
Sbjct: 20307 ---VERRDLPDGRWTKASFTNVTETQFIISGLTQNSQYEFRVFARNAVGSISNPSEVVGP 20363
Query: 1082 FTTLQ----PGSSIPPYNTEVTE----TTIV----ITWTPAPRI-GFKLGVRPSQGGEAP 1128
T + P +P TEV + T++ I+ PAP I +K
Sbjct: 20364 ITCIDSYGGPVIDLPLEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVC 20423
Query: 1129 REVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDT 1188
E T+D SI++ Y +++ A I +++ PP
Sbjct: 20424 VENTTDLASILIKDADRLNSGCYELKLRNAMGSASATIRVQILDKPGPPGGPIEFKTVTA 20483
Query: 1189 GVLTVSWERSTTPD----ITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYN 1244
+T+ W R D IT Y + T+ + + E H ++ T + G EY
Sbjct: 20484 EKITLLW-RPPADDGGAKITHYIVEKRETSRVVWSMVSE--HLEECIITTTKIIKGNEYI 20540
Query: 1245 VSVYTVKDDKESVPI-SDTII----------PEVPQLTDLSFVDITDSSIGLRWT-PL-- 1290
V V P+ SD+++ P +P++T IT +S+ + W+ P+
Sbjct: 20541 FRVRAVNKYGIGEPLESDSVVAKNAFVTPGPPGIPEVT-----KITKNSMTVVWSRPIAD 20595
Query: 1291 NSSTIIGYRITVVAAGEGIPIFEDFVDSSVGYY------------TVTGLEPGIDYDISV 1338
S I GY E S+G++ VTGL DY V
Sbjct: 20596 GGSDISGY------------FLEKRDKKSLGWFKVLKETIRDTRQKVTGLTENSDYQYRV 20643
Query: 1339 ITLINGGE---SAPTTLTQQTAVP-----PPTDLRFTNIGPDTMRVTWAPP---PSIDLT 1387
+ G+ S P+ + A P PP +R + ++ + W+ P +T
Sbjct: 20644 CAVNAAGQGPFSEPSEF-YKAADPIDPPGPPAKIRIADSTKSSITLGWSKPVYDGGSAVT 20702
Query: 1388 NFLVRYSPVKNEE-DVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQ- 1445
++V + EE V++NL PG Y VS+V + P+ +
Sbjct: 20703 GYVVEIRQGEEEEWTTVSTKGEVRTTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEP 20762
Query: 1446 ---KTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRN 1502
K L++P ID S + ++ R P + ++ +R
Sbjct: 20763 VQAKDILEAPE-IDLDVALRTSVIAKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARY 20821
Query: 1503 SI---------TLTNLTPGT--EYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAAT 1551
SI T+ +T +Y+++I G +S + + + L+V +
Sbjct: 20822 SIENTDSSSLLTIPQVTRNDTGKYILTIENGVGEPKSSTVSVKVLDTPAACQKLQVKHVS 20881
Query: 1552 PTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGL-----KPGVDYT 1606
++ + WD P + I Y ++ + ++V K ++T L K +
Sbjct: 20882 RGTVTLLWDPPLIDGGSPIINYVIEKRDATKRTWSVVSHKCSSTSFKLIDLSEKTPFFFR 20941
Query: 1607 ITVYAVTGRGDSPASSKPISINYRTEIDKP-SQMQVTDVQDNSISVKW----LPSSSPVT 1661
+ G G+ +++P+ E+ P + + D S+ + W S +T
Sbjct: 20942 VLAENEIGIGEPCETTEPVK---AAEVPAPIRDLSMKDSTKTSVILSWTKPDFDGGSVIT 20998
Query: 1662 GYRVTTTPKNGPGPTKTKTAGPDQT-EMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAV 1720
Y V + G G AG +T E+ + L+ V+A+N G S P+ +
Sbjct: 20999 EYVV---ERKGKGEQTWSHAGISKTCEIEVSQLKEQSVLEFRVFAKNEKGLSDPVTIGPI 21055
Query: 1721 TNIDRPKGLAFT-DVDVDSIKIAWESPQ-GQVSRYRVTY-SSPEDGIHEL---FPAPDGE 1774
T K L T +VD+ I A + + G + Y P+ I L P + E
Sbjct: 21056 T----VKELIITPEVDLSDIPGAQVTVRIGHNVHLELPYKGKPKPSISWLKDGLPLKESE 21111
Query: 1775 -------EDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPT----DLKFTQ 1823
E+ L E+ + D+ + + + P+ ++F +
Sbjct: 21112 FVRFSKTENKITLSIKNAKKEHGGKYTVILDNAVCRIAVPITVITLGPPSKPKGPIRFDE 21171
Query: 1824 VTPTSLSAQWTPP----NVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKY 1879
+ S+ W P ++T Y + +T K + + ++ V L+ +Y
Sbjct: 21172 IKADSVILSWDVPEDNGGGEITCYSIEKRETSQTN-WKMVCSSVARTTFKVPNLVKDAEY 21230
Query: 1880 EVSVYALKDTLTSRPAQGVVTTLEN----VSPPRRARVTDATETTITISWRTKT----ET 1931
+ V A S+P + ++ PP + + + T ++++W
Sbjct: 21231 QFRVRAENRYGVSQPLVSSIIVAKHQFRIPGPPGKPVIYNVTSDGMSLTWDAPVYDGGSE 21290
Query: 1932 ITGFQVDAVPANGQTPIQRTIKP-DVRSYTITGLQPGTDYKIYLYTLNDNARSSP----V 1986
+TGF V+ N + P R Y TGL G DY+ +Y N SSP
Sbjct: 21291 VTGFHVEKKERNSILWQKVNTSPISGREYRATGLVEGLDYQFRVYAENSAGLSSPSDPSK 21350
Query: 1987 VIDASTAIDAPSNLRFLATTPNSLLVSWQPP----RARITGYIIKYEKPGSPPREVVPRP 2042
A + +D P ++ T ++ + W PP ++I GY I+ ++ G+
Sbjct: 21351 FTLAVSPVDPPGTPDYIDVTRETITLKWNPPLRDGGSKIVGYSIE-KRQGNERWVRCNFT 21409
Query: 2043 RPGVTEATITGLEPGTEYTIYVIA 2066
+ T+TGL PG Y +IA
Sbjct: 21410 DVSECQYTVTGLSPGDRYEFRIIA 21433
Score = 109 bits (272), Expect = 4e-23
Identities = 299/1423 (21%), Positives = 501/1423 (35%), Gaps = 243/1423 (17%)
Query: 728 VTEITASSFVVSW----VSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPG 783
+++I A + +SW ++ + VE GD L T TS + L+PG
Sbjct: 12504 ISDIDADACSLSWHIPLEDGGSNITNYIVEKCDVSRGDWVTAL-ASVTKTSCRVGKLIPG 12562
Query: 784 RKYIVNV-----YQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ--- 835
++YI V + ISE +++ P P + V +V+ I V W RP
Sbjct: 12563 QEYIFRVRAENRFGISEPLTSPKMVAQFPFGVPSEPKNARVTKVNKDCIFVAWDRPDSDG 12622
Query: 836 -APITGYRIVYSPS-----VEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQES 889
+PI GY I V+ + T + E + L G++Y+ IYA+ + S
Sbjct: 12623 GSPIIGYLIERKERNSLLWVKANDTLVRSTE----YPCAGLVEGLEYSFRIYALNKAGSS 12678
Query: 890 TPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPVN 945
P + T D P + ++VT V+++W P+ S + GY V+
Sbjct: 12679 PPSKPTEYVTARMPVDPPGKP---EVIDVTKSTVSLIWARPKHDGGSKIIGYFVEA--CK 12733
Query: 946 LPGEHGQRLPISRNTFAE----VTGLSPGVTYYFKVF---AVSHGRESKPLTAQQTTKLD 998
LPG+ R + + + TGL Y F+ AV+ S+P +
Sbjct: 12734 LPGDKWVRCNTAPHQIPQEEYTATGLEEKAQYQFRAIARTAVNISPPSEPSDPVTILAEN 12793
Query: 999 APTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQ----------YNVGPSV 1048
P + S + V+ G + + T G+P +
Sbjct: 12794 VPPRIDLSVAMKSLLTVK--------AGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGI 12845
Query: 1049 SKYPLRNL----------QPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEV 1098
RNL + + +YT++ G++ + V +PG PP + ++
Sbjct: 12846 KMAMQRNLCTLELFSVNRKDSGDYTITAENSSGSKSATIKLKVLD--KPG---PPASVKI 12900
Query: 1099 TE---TTIVITWTPAPRIG------FKLGVR-PSQGGEAPREVTSDSGSIVVSGLTPGVE 1148
+ +++W P G + + R S+ A T S V L G E
Sbjct: 12901 NKMYSDRAMLSWEPPLEDGGSEITNYIVDKRETSRPNWAQVSATVPITSCSVEKLIEGHE 12960
Query: 1149 YVYTIQVLRDGQERDAPIVNKVV--TPLSPPTNLH--LEANPDTGVLTVSWERSTT---P 1201
Y + I D + P PP + +N +TVSW+
Sbjct: 12961 YQFRICAENKYGVGDPVFTEPAIAKNPYDPPGRCDPPVISNITKDHMTVSWKPPADDGGS 13020
Query: 1202 DITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTV--------KDD 1253
ITGY + T + ++ + L G EY V + D
Sbjct: 13021 PITGYLLEKRETQAVNWTKVNRKPIIER-TLKATGLQEGTEYEFRVTAINKAGPGKPSDA 13079
Query: 1254 KESVPISDTIIPEVPQLTDLSFVDITDSSIGLRWTPL---NSSTIIGYRITVVAAGEGIP 1310
++ D P P + D T SS+ L W S IIGY + V A
Sbjct: 13080 SKAAYARDPQYPPGPPAFPKVY-DTTRSSVSLSWGKPAYDGGSPIIGYLVEVKRADS--- 13135
Query: 1311 IFEDFVDSSVGY------YTVTGLEPGIDYDISVITLINGGESAPTTL-----TQQTAVP 1359
+++V ++ + VTGL Y V + G S P+ + + +P
Sbjct: 13136 --DNWVRCNLPQNLQKTRFEVTGLMEDTQYQFRVYAVNKIGYSDPSDVPDKHYPKDILIP 13193
Query: 1360 P----PTDLRFTNI--GPDTMR----VTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISP 1409
P DLR T I TMR V PPP I + P N D L I
Sbjct: 13194 PEGELDADLRKTLILRAGVTMRLYVPVKGRPPPKITWS------KPNVNLRDRIGLDIKS 13247
Query: 1410 SDNAVVL----TNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSF 1465
+D L N +Y++++ + + E T + T P + +I+ +S
Sbjct: 13248 TDFDTFLRCENVNKYDAGKYILTLENSCGKKEYTIVVKVLDTP-GPPVNVTVKEISKDSA 13306
Query: 1466 TVHWIAP----RATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVA 1521
V W P + I Y ++ S+ S + NL G Y + A
Sbjct: 13307 YVTWEPPIIDGGSPIINYVVQKRDAERKSWSTV-TTECSKTSFRVANLEEGKSYFFRVFA 13365
Query: 1522 LNGREESPLLIGQQSTVSDVPR---------DLEVVAATPTSLLISWDAPAVTVRYYRIT 1572
E+ IG D + DL+V + + +S I W P I
Sbjct: 13366 -----ENEYGIGDPGETRDAVKASQTPGPVVDLKVRSVSKSSCSIGWKKPHSDGGSRIIG 13420
Query: 1573 YGETGGNSPVQEFTVPGSKSTATISGLK---------PGVDYTITVYAVTGRGDSPASSK 1623
Y V +F +K + L G +YT V A G+ S
Sbjct: 13421 Y--------VVDFLTEENKWQRVMKSLSLQYSAKDLTEGKEYTFRVSAENENGEGTPSE- 13471
Query: 1624 PISINYRTEIDKPSQMQVTDVQDNSISVKWLPS----SSPVTGYRVTTTPKNGPGPTKTK 1679
I++ R ++ P + +K LP + + +R+ K P P+ +
Sbjct: 13472 -ITVVARDDVVAP-----------DLDLKGLPDLCYLAKENSNFRLKIPIKGKPAPSVSW 13519
Query: 1680 TAGPD----QTEMTIEGLQPTVEYVV-----------SVYAQNPSGESQPLVQTAVTNID 1724
G D T +++E +V ++ +N +G + + V
Sbjct: 13520 KKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKEGTISIKVVGKP 13579
Query: 1725 R-PKG-LAFTDVDVDSIKIAWESPQGQVSRYRVTY-SSPEDGIHELFP--APDGEEDTAE 1779
P G + F +V +++ + W P+ Y D ++ + A ++ T
Sbjct: 13580 GIPTGPIKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDSVNNKWVTCASAVQKTTFR 13639
Query: 1780 LQGLRPGSEYTVSVVA-----LHDDMESQPLIGTQSTAIP-APTDLKFTQVTPTSLSAQW 1833
+ L G EYT V A + + ++S+P++ +P AP V S+S W
Sbjct: 13640 VTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVPDAPPPPNIVDVRHDSVSLTW 13699
Query: 1834 TPP----NVQLTGYRVRVTPKEKTGPM-KEINLAP-DSSSVVVSGLMVATKYEVSVYAL- 1886
T P +TGY + KE+ + K N P V+GL +YE V A+
Sbjct: 13700 TDPKKTGGSPITGYHLEF--KERNSLLWKRANKTPIRMRDFKVTGLTEGLEYEFRVMAIN 13757
Query: 1887 -----KDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKT----ETITGFQV 1937
K +L S P V L+ + PP + V + T ++T+ W +TG+ V
Sbjct: 13758 LAGVGKPSLPSEP----VVALDPIDPPGKPEVINITRNSVTLIWTEPKYDGGHKLTGYIV 13813
Query: 1938 DA--VPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLN 1978
+ +P+ P+ ++T+T L G Y+ + N
Sbjct: 13814 EKRDLPSKSWMKANHVNVPEC-AFTVTDLVEGGKYEFRIRAKN 13855
Score = 108 bits (269), Expect = 9e-23
Identities = 265/1341 (19%), Positives = 468/1341 (34%), Gaps = 163/1341 (12%)
Query: 780 LLPGRKYIVNVYQISEDGE----QSLILSTSQTTAPDAPPD-PTVDQVDDTSIVVRWSRP 834
L+ G +YI V ++ G+ QS + P PP+ P V V + V W RP
Sbjct: 14039 LIQGNEYIFRVSAVNHYGKGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSWKRP 14098
Query: 835 Q----APITGYRIVYSPSVEGSSTE-LNLPETANSVTLSDLQPGVQYNITIYA-----VE 884
+ ITGY + + P + ++ LQ G Y + A +
Sbjct: 14099 VDDGGSEITGYHVERREKKSLRWVRAIKTPVSDLRCKVTGLQEGSTYEFRVSAENRAGIG 14158
Query: 885 ENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPES----AVTGYRVD 940
E++ V+ ++ P + P D T ++ W P +TGY V+
Sbjct: 14159 PPSEASDSVLMKDAAYPPGPPSNPHVTD-----TTKKSASLAWGKPHYDGGLEITGYVVE 14213
Query: 941 VIPVN----LPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQ--QT 994
V + G L I++ V L Y F++ A++ +P +
Sbjct: 14214 HQKVGDEAWIKDTTGTALRITQFV---VPDLQTKEKYNFRISAINDAGVGEPAVIPDVEI 14270
Query: 995 TKLDAPTNLQFVNETDSTVLVR-------WTP----PRAQITGYRLTVGLTRRGQPRQYN 1043
+ + + + E T++VR + P P ++T + + L R
Sbjct: 14271 VEREMAPDFELDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKNRANIENTE 14330
Query: 1044 VGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTI 1103
++ P N ++ +++ G + V T P ++ P T++T+ ++
Sbjct: 14331 -SFTLLIIPECNRYDTGKFVMTIENPAGKKSGFVNVRVLDTPGPVLNLRP--TDITKDSV 14387
Query: 1104 VITWT-PAPRIGFKLGVRPSQGGEAPREVTSDSGS------IVVSGLTPGVEYVYTIQVL 1156
+ W P G ++ + EA R+ S + + V+GL+ G EY + +
Sbjct: 14388 TLHWDLPLIDGGSRITNYIVEKREATRKSYSTATTKCHKCTYKVTGLSEGCEYFFRVMAE 14447
Query: 1157 RD---GQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPD---ITGYRITT 1210
+ G+ + K SPP +L++ + ++++W + ITGY I
Sbjct: 14448 NEYGIGEPTETTEPVKASEAPSPPDSLNI-MDITKSTVSLAWPKPKHDGGSKITGYVIEA 14506
Query: 1211 TPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISD--TIIPEVP 1268
Q + V + C NL+ G EY V V S P I+ E
Sbjct: 14507 QRKGSDQWTHITTVKGLE---CVVRNLTEGEEYTFQVMAVNSAGRSAPRESRPVIVKEQT 14563
Query: 1269 QLTDLSFVDITDSSIGLRWTPLNSSTI--IGYRITVVAAGEGIPI--------FEDFVDS 1318
L +L I + + I +G V +G I FE S
Sbjct: 14564 MLPELDLRGIYQKLVIAKAGDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATS 14623
Query: 1319 SVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTW 1378
++ Y ++ ++ T PP ++F + D + +W
Sbjct: 14624 TILNINECVRSDSGPYPLTARNIVGEVGDVITIQVHDIPGPPTGPIKFDEVSSDFVTFSW 14683
Query: 1379 APPPS---IDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSS---- 1431
PP + + ++N++V + V EL+ + T L G EY V +
Sbjct: 14684 DPPENDGGVPISNYVVEMRQTDSTTWV-ELATTVIRTTYKATRLTTGLEYQFRVKAQNRY 14742
Query: 1432 -VYEQHESTPLRGRQKTGLDSPTGI-DFSDITANSFTVHWIAP----RATITGYRIRHHP 1485
V S + + P G + +T +S T+ W P + I GY +
Sbjct: 14743 GVGPGITSACIVANYPFKVPGPPGTPQVTAVTKDSMTISWHEPLSDGGSPILGYHVERKE 14802
Query: 1486 EHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN-------GREESPLLIGQQSTV 1538
+ + N + LT G Y ++A N + P+L
Sbjct: 14803 RNGILWQTVSKALVPGNIFKSSGLTDGIAYEFRVIAENMAGKSKPSKPSEPMLALDPIDP 14862
Query: 1539 SDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPG----SKSTA 1594
P L + T T + W P T + +Y + P + ++
Sbjct: 14863 PGKPVPLNITRHTVT---LKWAKPEYTGGFKITSYIVEKRDLPNGRWLKANFSNILENEF 14919
Query: 1595 TISGLKPGVDYTITVYAVTGRGD-SPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKW 1653
T+SGL Y V A G SP S +I R +++ P +D I
Sbjct: 14920 TVSGLTEDAAYEFRVIAKNAAGAISPPSEPSDAITCRDDVEAPKIKVDVKFKDTVI---- 14975
Query: 1654 LPSSSPVTGYRVTTTPKNGPGPTK------TKTAGPDQTEMTIEGLQPTV---------E 1698
+R+ P PT + G + E+ I +
Sbjct: 14976 ---LKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDS 15032
Query: 1699 YVVSVYAQNPSGESQPLVQTAVTNIDRP----KGLAFTDVDVDSIKIAWESP---QGQVS 1751
++ A NP G ++ + V +DRP LA T+V + ++W P G
Sbjct: 15033 GAYTLTATNPGGFAKHIFNVKV--LDRPGPPEGPLAVTEVTSEKCVLSWFPPLDDGGAKI 15090
Query: 1752 RYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALH-----DDMESQPLI 1806
+ + + A + + ++ L G+EY V+A++ + +ES+P++
Sbjct: 15091 DHYIVQKRETSRLAWTNVASEVQVTKLKVTKLLKGNEYIFRVMAVNKYGVGEPLESEPVL 15150
Query: 1807 GTQSTAIP-APTDLKFTQVTPTSLSAQWTPPN----VQLTGYRVRVTPKEKTGPMKEINL 1861
P P + + T +T S+ W P+ ++ Y V K +K
Sbjct: 15151 AVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEIINYIVERRDKAGQRWIKCNKK 15210
Query: 1862 APDSSSVVVSGLMVATKYEVSVYA-----LKDTLTSRPAQGVVTTLENVSPPRRARVTDA 1916
VSGL +YE + A + + P T+ PP RV D
Sbjct: 15211 TLTDLRYKVSGLTEGHEYEFRIMAENAAGISAPSPTSPFYKACDTVFKPGPPGNPRVLDT 15270
Query: 1917 TETTITISWRTKT----ETITGFQVD-AVPANGQTPIQRTIKP----DVRSYTITGLQPG 1967
+ ++I+I+W ITG+ V+ A+P + I + P SYTITGL
Sbjct: 15271 SRSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQI---VTPPAGLKATSYTITGLTEN 15327
Query: 1968 TDYKIYLYTLNDNARSSPVVI 1988
+YKI +Y +N P ++
Sbjct: 15328 QEYKIRIYAMNSEGLGEPALV 15348
Score = 106 bits (265), Expect = 2e-22
Identities = 320/1538 (20%), Positives = 543/1538 (35%), Gaps = 226/1538 (14%)
Query: 702 TSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSW----VSASDTVSGFRVEYELS 757
T P S V +T P VT+++ V W +++G+ +E
Sbjct: 11881 TGPPTESKPVIAKTKYDKPGRPDPPEVTKVSKEEMTVVWNPPEYDGGKSITGYFLE---K 11937
Query: 758 EEGDEPQYLDLPSTATS---VNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDA- 813
+E +++ + +A + + +LLP +Y V +E G L + A D
Sbjct: 11938 KEKHSTRWVPVNKSAIPERRMKVQNLLPDHEYQFRVKAENEIGIGEPSLPSRPVVAKDPI 11997
Query: 814 --PPDPTVDQVDDT---SIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANS 864
P PT +V DT SI + W +P API GY + P + +S + +
Sbjct: 11998 EPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAPIIGYVVEMRPKIADASPDEGWKRCNAA 12057
Query: 865 VTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGT------------------PRSDT 906
L V+ T+ +++ENQE V Q G P D
Sbjct: 12058 AQL------VRKEFTVTSLDENQEYEFRVCAQNQVGIGRPAELKEAIKPKEILEPPEIDL 12111
Query: 907 VPSPRDLQFVEV-TDVKV-TIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEV 964
S R L V +++ I+ P VT +V + V GQ + F +
Sbjct: 12112 DASMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVV---RKGQVDLVDTMAFLVI 12168
Query: 965 TGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAP-TNLQFVNETDSTVLVRWTPPR-- 1021
+ + + + V+ E + P ++L+ + T ++ V W PP
Sbjct: 12169 PNSTRDDSGKYSLTLVNPAGEKAVFVNVRVLDTPGPVSDLKVSDVTKTSCHVSWAPPEND 12228
Query: 1022 --AQITGYRLTVGLTRRGQPRQYNVGPSVSK--YPLRNLQPASEYTVSLVAIKGNQESPK 1077
+Q+T Y V + V P V K + + NL P +EY + A+ N+ P
Sbjct: 12229 GGSQVTHY--IVEKREADRKTWSTVTPEVKKTSFHVTNLVPGNEYYFRVTAV--NEYGPG 12284
Query: 1078 ATG-----VFTTLQPGSSIPPYNTEVTETT---IVITWTPAPRIG-FKLG--VRPSQGGE 1126
V + PP EVTE T + W P R G K+ + + E
Sbjct: 12285 VPTDVPKPVLASDPLSEPDPPRKLEVTEMTKNSATLAWLPPLRDGGAKIDGYITSYREEE 12344
Query: 1127 APREVTSDSG-----SIVVSGLTPGVEYVYTI---QVLRDGQERDAPIVNKVVTPLSPPT 1178
P + ++ S+VV+GL G +Y + + + R+A V + L PP
Sbjct: 12345 QPADRWTEYSVVKDLSLVVTGLKEGKKYKFRVAARNAVGVSLPREAEGVYEAKEQLLPPK 12404
Query: 1179 NL-----------------HLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSL 1221
L H+ P T W++ +T + + +
Sbjct: 12405 ILMPEQITIKAGKKLRIEAHVYGKPHP---TCKWKKGEDEVVTSSHLAVHKADSSSILII 12461
Query: 1222 EEVVHADQS--SCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPEVPQLTDLSFVDIT 1279
++V D S T +N S K V + D P P D+S DI
Sbjct: 12462 KDVTRKDSGYYSLTAENSSG----------TDTQKIKVVVMDAPGPPQPPF-DIS--DID 12508
Query: 1280 DSSIGLRW-TPLNS--STIIGYRITV--VAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDY 1334
+ L W PL S I Y + V+ G+ + +S V L PG +Y
Sbjct: 12509 ADACSLSWHIPLEDGGSNITNYIVEKCDVSRGDWVTALASVTKTSC---RVGKLIPGQEY 12565
Query: 1335 DISVITLINGGESAPTTLTQQTAVPP------PTDLRFTNIGPDTMRVTWAPPPSIDLTN 1388
V G S P T + A P P + R T + D + V W P S D +
Sbjct: 12566 IFRVRAENRFGISEPLTSPKMVAQFPFGVPSEPKNARVTKVNKDCIFVAWDRPDS-DGGS 12624
Query: 1389 FLVRYSPVKNEEDVAELSISPSDNAVVLTN-----LLPGTEYVVSVSSVYEQHESTPLRG 1443
++ Y ++ +E + L + +D V T L+ G EY + ++ + S P +
Sbjct: 12625 PIIGYL-IERKERNSLLWVKANDTLVRSTEYPCAGLVEGLEYSFRIYALNKAGSSPPSKP 12683
Query: 1444 RQ----KTGLDSPTGIDFSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPRED 1495
+ + +D P + D+T ++ ++ W P+ + I GY + R +
Sbjct: 12684 TEYVTARMPVDPPGKPEVIDVTKSTVSLIWARPKHDGGSKIIGYFVEACKLPGDKWVRCN 12743
Query: 1496 RVPHS--RNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTV---SDVPRDLEVVAA 1550
PH + T T L +Y +A SP +VP +++ A
Sbjct: 12744 TAPHQIPQEEYTATGLEEKAQYQFRAIARTAVNISPPSEPSDPVTILAENVPPRIDLSVA 12803
Query: 1551 TPTSLLIS------WDAPAVTVRYYRITYGETGGN-SPVQEFTVPGSKSTATIS----GL 1599
+ L + DA +++ + G P + + ++ T+
Sbjct: 12804 MKSLLTVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNR 12863
Query: 1600 KPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLP---- 1655
K DYTIT S + S I + + P+ +++ + + + W P
Sbjct: 12864 KDSGDYTITA-----ENSSGSKSATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLED 12918
Query: 1656 SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPL 1715
S +T Y V + P + P T ++E L EY + A+N G P+
Sbjct: 12919 GGSEITNYIVDKRETSRPNWAQVSATVPI-TSCSVEKLIEGHEYQFRICAENKYGVGDPV 12977
Query: 1716 -VQTAVT-NIDRPKGLA----FTDVDVDSIKIAWESPQGQ----VSRYRVTYSSPEDGIH 1765
+ A+ N P G +++ D + ++W+ P ++ Y + +
Sbjct: 12978 FTEPAIAKNPYDPPGRCDPPVISNITKDHMTVSWKPPADDGGSPITGYLLEKRETQAVNW 13037
Query: 1766 ELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAI------PAPTDL 1819
E T + GL+ G+EY V A++ +P +++ P P
Sbjct: 13038 TKVNRKPIIERTLKATGLQEGTEYEFRVTAINKAGPGKPSDASKAAYARDPQYPPGPPAF 13097
Query: 1820 -KFTQVTPTSLSAQWTPPNVQ----LTGYRVRVTPKEKTGPMKEINLAPD--SSSVVVSG 1872
K T +S+S W P + GY V V + ++ NL + + V+G
Sbjct: 13098 PKVYDTTRSSVSLSWGKPAYDGGSPIIGYLVEVKRADSDNWVR-CNLPQNLQKTRFEVTG 13156
Query: 1873 LMVATKYEVSVYALKDTLTSRPAQ--GVVTTLENVSPPRRARVTDATETTITISWRTKTE 1930
LM T+Y+ VYA+ S P+ + + PP D +T I + T
Sbjct: 13157 LMEDTQYQFRVYAVNKIGYSDPSDVPDKHYPKDILIPPEGELDADLRKTLILRAGVTMRL 13216
Query: 1931 TITGFQVDAVPANGQTPIQRT-IKPDVRSYTITGLQ-PGTDYKIYLYTLNDN-------- 1980
VP G+ P + T KP+V GL TD+ +L N N
Sbjct: 13217 --------YVPVKGRPPPKITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKYI 13268
Query: 1981 --------ARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPP----RARITGYIIKY 2028
+ +V+ P N+ + +S V+W+PP + I Y+++
Sbjct: 13269 LTLENSCGKKEYTIVVKVLDTPGPPVNVTVKEISKDSAYVTWEPPIIDGGSPIINYVVQK 13328
Query: 2029 EKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIA 2066
V T + LE G Y V A
Sbjct: 13329 RDAERKSWSTV-TTECSKTSFRVANLEEGKSYFFRVFA 13365
Score = 102 bits (255), Expect = 4e-21
Identities = 274/1373 (19%), Positives = 474/1373 (34%), Gaps = 187/1373 (13%)
Query: 766 LDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDT 825
+DL T + IP+ ++ ++ GE+++ ++ P D V V T
Sbjct: 12157 VDLVDTMAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFVNVRVLDTPGPVSDLKVSDVTKT 12216
Query: 826 SIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETAN-SVTLSDLQPGVQYNITI 880
S V W+ P+ + +T Y IV + + PE S +++L PG +Y +
Sbjct: 12217 SCHVSWAPPENDGGSQVTHY-IVEKREADRKTWSTVTPEVKKTSFHVTNLVPGNEYYFRV 12275
Query: 881 YAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTG 936
AV E P + + + PR L+ E+T T+ W PP + + G
Sbjct: 12276 TAVNEYGPGVPTDVPKPVLASDPLSEPDPPRKLEVTEMTKNSATLAWLPPLRDGGAKIDG 12335
Query: 937 YRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTK 996
Y P + + ++ VTGL G Y F+V A+
Sbjct: 12336 YITSYREEEQPADRWTEYSVVKDLSLVVTGLKEGKKYKFRV------------AARNAVG 12383
Query: 997 LDAPTNLQFVNETDSTVLVRWTPPR----AQIT---GYRLTVGLTRRGQPR--------- 1040
+ P + V E +L PP+ QIT G +L + G+P
Sbjct: 12384 VSLPREAEGVYEAKEQLL----PPKILMPEQITIKAGKKLRIEAHVYGKPHPTCKWKKGE 12439
Query: 1041 ---------QYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSI 1091
+ S S ++++ SL A + + V PG
Sbjct: 12440 DEVVTSSHLAVHKADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPGPPQ 12499
Query: 1092 PPYN-TEVTETTIVITW-TPAPRIGFKL------GVRPSQGGEAPREVTSDSGSIVVSGL 1143
PP++ +++ ++W P G + S+G + S V L
Sbjct: 12500 PPFDISDIDADACSLSWHIPLEDGGSNITNYIVEKCDVSRGDWVTALASVTKTSCRVGKL 12559
Query: 1144 TPGVEYVYTIQVLRDGQERDAPIVNKVV------TPLSPPTNLHLEANPDTGVLTVSWER 1197
PG EY++ ++ + K+V P P + N D + V+W+R
Sbjct: 12560 IPGQEYIFRVRAENRFGISEPLTSPKMVAQFPFGVPSEPKNARVTKVNKD--CIFVAWDR 12617
Query: 1198 STT---PDITGYRITTTPTNGQQG-NSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDD 1253
+ I GY I N + + +V + + C L GLEY+ +Y +
Sbjct: 12618 PDSDGGSPIIGYLIERKERNSLLWVKANDTLVRSTEYPCA--GLVEGLEYSFRIYALNKA 12675
Query: 1254 KESVPISDTIIPEVPQLTD----LSFVDITDSSIGLRWTPL---NSSTIIGYRITVV--- 1303
S P T D +D+T S++ L W S IIGY +
Sbjct: 12676 GSSPPSKPTEYVTARMPVDPPGKPEVIDVTKSTVSLIWARPKHDGGSKIIGYFVEACKLP 12735
Query: 1304 --------AAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVI--TLIN----GGESAP 1349
A IP E YT TGLE Y I T +N S P
Sbjct: 12736 GDKWVRCNTAPHQIPQEE---------YTATGLEEKAQYQFRAIARTAVNISPPSEPSDP 12786
Query: 1350 TTLTQQTAVPPPTDLRF-----------TNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKN 1398
T+ + VPP DL TN+ D V P P++ P +
Sbjct: 12787 VTILAEN-VPPRIDLSVAMKSLLTVKAGTNVCLDA-TVFGKPMPTVSWKKDGTLLKPAEG 12844
Query: 1399 EEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHEST-PLRGRQKTGLDSPTGIDF 1457
+ + ++ + + N +Y ++ + +T L+ K G P +
Sbjct: 12845 IKMAMQRNLCTLE--LFSVNRKDSGDYTITAENSSGSKSATIKLKVLDKPG--PPASVKI 12900
Query: 1458 SDITANSFTVHWIAP----RATITGYRIRHHPEHFSGRPREDRVPHS--RNSITLTNLTP 1511
+ + ++ + W P + IT Y + + + RP +V + S ++ L
Sbjct: 12901 NKMYSDRAMLSWEPPLEDGGSEITNYIV---DKRETSRPNWAQVSATVPITSCSVEKLIE 12957
Query: 1512 GTEYVVSIVALNGREESPLLIGQQSTVS---DVPR--DLEVVA-ATPTSLLISWDAPA-- 1563
G EY I A N + + + D P D V++ T + +SW PA
Sbjct: 12958 GHEYQFRICAENKYGVGDPVFTEPAIAKNPYDPPGRCDPPVISNITKDHMTVSWKPPADD 13017
Query: 1564 --VTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRG---DS 1618
+ Y + ET + + P + T +GL+ G +Y V A+ G S
Sbjct: 13018 GGSPITGYLLEKRETQAVNWTKVNRKPIIERTLKATGLQEGTEYEFRVTAINKAGPGKPS 13077
Query: 1619 PASSKPISINYRTEIDKPSQMQVTDVQDNSISVKW----LPSSSPVTGYRVTTTPKNGPG 1674
AS + + + P+ +V D +S+S+ W SP+ GY V +
Sbjct: 13078 DASKAAYARDPQYPPGPPAFPKVYDTTRSSVSLSWGKPAYDGGSPIIGYLVEVKRADSDN 13137
Query: 1675 PTKTK-TAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFT- 1732
+ +T + GL +Y VYA N G S P + V + PK +
Sbjct: 13138 WVRCNLPQNLQKTRFEVTGLMEDTQYQFRVYAVNKIGYSDP---SDVPDKHYPKDILIPP 13194
Query: 1733 --DVDVDSIKIAWESPQGQVSRY---------RVTYSSPEDGIHELFPAPDGEED----- 1776
++D D K + Y ++T+S P + + D
Sbjct: 13195 EGELDADLRKTLILRAGVTMRLYVPVKGRPPPKITWSKPNVNLRDRIGLDIKSTDFDTFL 13254
Query: 1777 TAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPP 1836
E +Y +++ E ++ T P P ++ +++ S W PP
Sbjct: 13255 RCENVNKYDAGKYILTLENSCGKKEYTIVVKVLDTPGP-PVNVTVKEISKDSAYVTWEPP 13313
Query: 1837 NVQ----LTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTS 1892
+ + Y V+ E+ + +S V+ L Y V+A +
Sbjct: 13314 IIDGGSPIINYVVQKRDAERKS-WSTVTTECSKTSFRVANLEEGKSYFFRVFAENEYGIG 13372
Query: 1893 RPAQ--GVVTTLENVSPPRRARVTDATETTITISWRTK----TETITGFQVDAVPANGQT 1946
P + V + P +V ++++ +I W+ I G+ VD + +
Sbjct: 13373 DPGETRDAVKASQTPGPVVDLKVRSVSKSSCSIGWKKPHSDGGSRIIGYVVDFLTEENKW 13432
Query: 1947 PIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSP--VVIDASTAIDAP 1997
QR +K Y+ L G +Y + N+N +P + + A + AP
Sbjct: 13433 --QRVMKSLSLQYSAKDLTEGKEYTFRVSAENENGEGTPSEITVVARDDVVAP 13483
Score = 102 bits (255), Expect = 4e-21
Identities = 306/1554 (19%), Positives = 528/1554 (33%), Gaps = 201/1554 (12%)
Query: 610 GPVEVFITETPSQPNSHPIQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSY 666
GP E + T + WN P ++IS YI+ R + + W + + +Y
Sbjct: 18306 GPPEGPLKVTGVTAEKCYLAWNPPLQDGGANISHYIIEKRETSRLS-WTQVSTEVQALNY 18364
Query: 667 TIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSE 726
+ L PG Y +++++ +YG E P+ S VT P ++
Sbjct: 18365 KVTKLLPGNEYIFRVMAVNKYGIGE-------------PLESGPVTACNPYKPPGPPSTP 18411
Query: 727 SVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDE-----PQYLDLPSTATSVNIPDLL 781
V+ IT S VV+W D G +E + E+ D+ + T + + L
Sbjct: 18412 EVSAITKDSMVVTWARPVDD-GGTEIEGYILEKRDKEGVRWTKCNKKTLTDLRLRVTGLT 18470
Query: 782 PGRKY-----IVNVYQISEDGEQSLILSTSQTTAPDAPP-DPTVDQVDDTSIVVRWSRP- 834
G Y N + E E S+ P PP +P V +S+ + WS+P
Sbjct: 18471 EGHSYEFRVAAENAAGVGEPSEPSVFYRACDALYPPGPPSNPKVTDTSRSSVSLAWSKPI 18530
Query: 835 ---QAPITGYRIVYSPSVEGSSTELNLPE--TANSVTLSDLQPGVQYNITIYAVEENQES 889
AP+ GY + + T P T++ L+ +YN I A+
Sbjct: 18531 YDGGAPVKGYVVEVKEAAADEWTTCTPPTGLQGKQFTVTKLKENTEYNFRICAINSEGVG 18590
Query: 890 TPVVIQQETTGTPRSD--TVPSPRDLQFVEVTDVKVTI-----MWTPPESAVTGYRVDVI 942
P + R + + DL+ V V T+ + PE V + + I
Sbjct: 18591 EPATLPGSVVAQERIEPPEIELDADLRKVVVLRASATLRLFVTIKGRPEPEVKWEKAEGI 18650
Query: 943 PVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTN 1002
+ + + VT G Y + G ++ + + AP N
Sbjct: 18651 LTD-RAQIEVTSSFTMLVIDNVTRFDSG--RYNLTLENNSGSKTAFVNVRVLDSPSAPVN 18707
Query: 1003 LQFVNETDSTVLVRWTPP----RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQP 1058
L +V + W PP A+IT Y + T R + + + + NLQ
Sbjct: 18708 LTIREVKKDSVTLSWEPPLIDGGAKITNYIVEKRETTRKAYATITNNCTKTTFRIENLQE 18767
Query: 1059 ASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYN------TEVTETTIVITW-TPAP 1111
Y ++A + E TT S PP +VT T I W P
Sbjct: 18768 GCSYYFRVLA---SNEYGIGLPAETTEPVKVSEPPLPPGRVTLVDVTRNTATIKWEKPES 18824
Query: 1112 RIGFKLG----VRPSQGGEAPREVTS-DSGSIVVSGLTPGVEYVYTIQVLR-----DGQE 1161
G K+ ++G E T + +SGLT G EYV+ + + D ++
Sbjct: 18825 DGGSKITGYVVEMQTKGSEKWSTCTQVKTLEATISGLTAGEEYVFRVAAVNEKGRSDPRQ 18884
Query: 1162 RDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDIT-GYRITTTPTNGQQGNS 1220
P++ + + + P L V D+ R T + G +
Sbjct: 18885 LGVPVIARDI-EIKPSVELPFH------TFNVKAREQLKIDVPFKGRPQATVNWRKDGQT 18937
Query: 1221 LEEVVHADQSS---CTFDNLSPGLEYNVSVY--TVKDDKESVPISDTII------PEVPQ 1269
L+E + SS T ++ + +V Y V + S+ + TII P P
Sbjct: 18938 LKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSNSAGSITVPITIIVLDRPGPPGPI 18997
Query: 1270 LTDLSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIFEDFVDSSVGYYT--VTG 1327
D +++ SI + W P +V E V +V + +
Sbjct: 18998 RID----EVSCDSITISWNPPEYDGGCQISNYIVEKKETTSTTWHIVSQAVARTSIKIVR 19053
Query: 1328 LEPGIDYDISVITLINGGESAPTTLTQQTA------VPPPTDLRFTNIGPDTMRVTWAPP 1381
L G +Y V G+S+ + + A PP + + TM VTW P
Sbjct: 19054 LTTGSEYQFRVCAENRYGKSSYSESSAVVAEYPFSPPGPPGTPKVVHATKSTMLVTWQVP 19113
Query: 1382 PSIDLTNFLVRYSPVKNEEDV---AELSISPSDNAVVLTNLLPGTEY--------VVSVS 1430
+ + + + K + I +D + ++ L G Y + +
Sbjct: 19114 VNDGGSRVIGYHLEYKERSSILWSKANKILIADTQMKVSGLDEGLMYEYRVYAENIAGIG 19173
Query: 1431 SVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPR----ATITGYRIRHHPE 1486
+ E P R D P + ++IT S ++ W P A ITGY + E
Sbjct: 19174 KCSKSCEPVPAR----DPCDPPGQPEVTNITRKSVSLKWSKPHYDGGAKITGYIVERR-E 19228
Query: 1487 HFSGRPREDRVPHSRNS-ITLTNLTPGTEYVVSIVALNGREE--------SPLLIGQQST 1537
GR + + + + +T LT Y + A N + P+++
Sbjct: 19229 LPDGRWLKCNYTNIQETYFEVTELTEDQRYEFRVFARNAADSVSEPSESTGPIIVKDDVE 19288
Query: 1538 VSDVPRDLE----VVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKST 1593
V D++ +V L I+ D + I++ + G + T S
Sbjct: 19289 PPRVMMDVKFRDVIVVKAGEVLKINADIAGRPLPV--ISWAKDGIEIEERARTEIISTDN 19346
Query: 1594 ATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKP----SQMQVTDVQDNSI 1649
T+ +K + Y +T + + A ++ +++N + +DKP +++ +
Sbjct: 19347 HTLLTVKDCIRRDTGQYVLTLK--NVAGTRSVAVNCKV-LDKPGPPAGPLEINGLTAEKC 19403
Query: 1650 SVKW---LPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQ 1706
S+ W Y + + T + L EY+ V
Sbjct: 19404 SLSWGRPQEDGGADIDYYIVEKRETSHLAWTICEGELQMTSCKVTKLLKGNEYIFRVTGV 19463
Query: 1707 NPSGESQPLVQTAVTNID------RPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSP 1760
N G +PL A+ +D P L T V +S+ + W P+ Y
Sbjct: 19464 NKYGVGEPLESVAIKALDPFTVPSPPTSLEITSVTKESMTLCWSRPESDGGSEISGYIIE 19523
Query: 1761 EDGIHELFPAPDGEEDTAELQ----GLRPGSEYTVSVVA-----LHDDMESQPLIGTQST 1811
+ L ++ +L+ GLR G EY V A L E+ PLI +
Sbjct: 19524 RREKNSLRWVRVNKKPVYDLRVKSTGLREGCEYEYRVYAENAAGLSLPSETSPLIRAEDP 19583
Query: 1812 A-IPA-PTDLKFTQVTPTSLSAQWTPP----NVQLTGYRVRVTPKEKTGPMKEINLAPDS 1865
+P+ P+ K T+++ W P +TGY V + T I +
Sbjct: 19584 VFLPSPPSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEYKKSDDTDWKTSIQ-SLRG 19642
Query: 1866 SSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENV----------SPPRRARVTD 1915
+ +SGL +Y V ++ S P+ + S R+ +
Sbjct: 19643 TEYTISGLTTGAEYVFRVKSVNKVGASDPSDSSDPQIAKEREEEPLFDIDSEMRKTLIVK 19702
Query: 1916 A-TETTITISWRTK-----------TETITGFQVDAVPANGQTPIQRTIKPDVRSYTITG 1963
A T+T+ +R + T+ T VD + I+ + D YT+T
Sbjct: 19703 AGASFTMTVPFRGRPVPNVLWSKPDTDLRTRAYVDTTDSRTSLTIENANRNDSGKYTLT- 19761
Query: 1964 LQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPP 2017
+Q +A S +V+ P+N+ T S ++SW P
Sbjct: 19762 IQNVL-----------SAASLTLVVKVLDTPGPPTNITVQDVTKESAVLSWDVP 19804
Score = 102 bits (255), Expect = 4e-21
Identities = 136/661 (20%), Positives = 242/661 (36%), Gaps = 91/661 (13%)
Query: 1514 EYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVT----VRYY 1569
+Y + +G++ + +L+ T P ++V + S+ I+W+ P + V Y
Sbjct: 23017 KYTIEAENQSGKKSATVLVKVYDTPGPCP-SVKVKEVSRDSVTITWEIPTIDGGAPVNNY 23075
Query: 1570 RITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYA--VTGRGDSPASSKPISI 1627
+ E + + T SK+ ISGL G Y V + G G+ +S + +
Sbjct: 23076 IVEKREAAMRA-FKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYGIGEPCETSDAVLV 23134
Query: 1628 NYRTEIDKPSQMQVTDVQDNSISVKW----LPSSSPVTGYRVTTTPKNGPGPTKTKTAGP 1683
+ + P++++V DV +++++ W S +TGY + K T P
Sbjct: 23135 SEVPLV--PAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGTERWMKVVTLKP 23192
Query: 1684 DQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAW 1743
E T+ L +Y+ + AQN G S+P + + L D+ K
Sbjct: 23193 TVLEHTVTSLNEGEQYLFRIRAQNEKGVSEPRETVTAVTVQDLRVLPTIDLSTMPQKTI- 23251
Query: 1744 ESPQGQVSRYRVTYSSPEDGIHELFPAPDG--EEDTAELQGLRPGSEYTVSVVALHDD-- 1799
P G+ + + F A E + ++ ++ T+ + D
Sbjct: 23252 HVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAKLTIRETTIRDTGE 23311
Query: 1800 --MESQPLIGTQSTAI---------PAPTDLKFTQVTPTSLSAQWTPPNVQ----LTGYR 1844
+E + + GT S I P +K ++ TS++ W PP + L+GY
Sbjct: 23312 YTLELKNVTGTTSETIKVIILDKPGPPTGPIKIDEIDATSITISWEPPELDGGAPLSGYV 23371
Query: 1845 VRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLEN 1904
V + G + P S SV S E + Y + T+R G E
Sbjct: 23372 VEQRDAHRPGWL------PVSESVTRSTFKFTRLTEGNEYVFRVAATNRFGIGSYLQSEV 23425
Query: 1905 VS---------PPRRARVTDATETTITISWRTKTET----ITGFQVDAVPANGQTPIQRT 1951
+ PP ++ D + +T++W + +TG+ V+ ++
Sbjct: 23426 IECRSSIRIPGPPETLQIFDVSRDGMTLTWYPPEDDGGSQVTGYIVERKEVRADRWVRVN 23485
Query: 1952 IKP-DVRSYTITGLQPGTDYKIYLYTLNDNARSSP-------VVIDASTAIDAPSNLRFL 2003
P + Y TGL G +Y+ + +N P V +D P N R
Sbjct: 23486 KVPVTMTRYRSTGLTEGLEYEHRVTAINARGSGKPSRPSKPIVAMDPIAPPGKPQNPRVT 23545
Query: 2004 ATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTE 2059
TT S+ ++W P +++TGY+I+ +K + E T+T L G E
Sbjct: 23546 DTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTKCNTTPTKIREYTLTHLPQGAE 23605
Query: 2060 YTIYVIALKNNQKSEPLIGRKKTDELPQLVTLPHPNLHGPEILDVPSTVQKTPFVTHPGY 2119
Y V+A EP +VP TV+ T + +P Y
Sbjct: 23606 YRFRVLACNAGGPGEP--------------------------AEVPGTVKVTEMLEYPDY 23639
Query: 2120 D 2120
+
Sbjct: 23640 E 23640
Score = 100 bits (248), Expect = 2e-20
Identities = 162/726 (22%), Positives = 275/726 (37%), Gaps = 92/726 (12%)
Query: 1268 PQLTDLSFVDITDSSIGLRWTPLN---SSTIIGYRITVVAAGEG--IPIFEDFVDSSVGY 1322
P + +I +SI + W P + + GY + A +P+ E S+
Sbjct: 23337 PPTGPIKIDEIDATSITISWEPPELDGGAPLSGYVVEQRDAHRPGWLPVSESVTRST--- 23393
Query: 1323 YTVTGLEPGIDYDISVITLINGG-----ESAPTTLTQQTAVP-PPTDLRFTNIGPDTMRV 1376
+ T L G +Y V G +S +P PP L+ ++ D M +
Sbjct: 23394 FKFTRLTEGNEYVFRVAATNRFGIGSYLQSEVIECRSSIRIPGPPETLQIFDVSRDGMTL 23453
Query: 1377 TWAPPPS---IDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVY 1433
TW PP +T ++V V+ + V + + T L G EY V+++
Sbjct: 23454 TWYPPEDDGGSQVTGYIVERKEVRADRWVRVNKVPVTMTRYRSTGLTEGLEYEHRVTAIN 23513
Query: 1434 EQHESTPLR-GRQKTGLD------SPTGIDFSDITANSFTVHWIAPR----ATITGYRIR 1482
+ P R + +D P +D T S ++ W P + +TGY I
Sbjct: 23514 ARGSGKPSRPSKPIVAMDPIAPPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIE 23573
Query: 1483 HHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVP 1542
+ + P TLT+L G EY ++A N G ++VP
Sbjct: 23574 MQKVDQHEWTKCNTTPTKIREYTLTHLPQGAEYRFRVLACNA--------GGPGEPAEVP 23625
Query: 1543 RDLEVVAAT--PTSLLISWDAPAVTVRY---YRITYGETGGNSPVQEFTVPGSKSTATIS 1597
++V P L + VR R+T G P+ ++T G + + +
Sbjct: 23626 GTVKVTEMLEYPDYELDERYQEGIFVRQGGVIRLTIPIKGKPFPICKWTKEG-QDISKRA 23684
Query: 1598 GLKPGVDYTITVYAVTGRGDS---------PASSKPISINYRTEIDKPSQ----MQVTDV 1644
+ +T V RGDS K + I R I P+ ++ D+
Sbjct: 23685 MIATSETHTELVIKEADRGDSGTYDLVLENKCGKKAVYIKVRV-IGSPNSPEGPLEYDDI 23743
Query: 1645 QDNSISVKWLPSS----SPVTGYRVTT--TPKNGPGPTKTKTAGPDQTEMTIEGLQPTVE 1698
Q S+ V W P + + + GY + PK ++ G T + ++GL+ VE
Sbjct: 23744 QVRSVRVSWRPPADDGGADILGYILERREVPKAAWYTIDSRVRG---TSLVVKGLKENVE 23800
Query: 1699 YVVSVYAQNPSGESQPLVQ----TAVTNIDRPKGLA----FTDVDVDSIKIAWESPQGQ- 1749
Y V A+N G S+PL T T ++ P+ + DV S+ ++W P+
Sbjct: 23801 YHFRVSAENQFGISKPLKSEEPVTPKTPLNPPEPPSNPPEVLDVTKSSVSLSWSRPKDDG 23860
Query: 1750 VSRYRVTYSSPEDGIHELFPAPDGEEDTAEL---QGLRPGSEYTVSVVALHD------DM 1800
SR Y ++ + + + + T + GL P +EY ++A +D
Sbjct: 23861 GSRVTGYYIERKETSTDKWVRHNKTQITTTMYTVTGLVPDAEYQFRIIAQNDVGLSETSP 23920
Query: 1801 ESQPLIGTQSTAIPA-PTDLKFTQVTPTSLSAQWTPPNV----QLTGYRVRVTPKEKTGP 1855
S+P++ P+ P +L+ ++ S++ QW P ++ GY V +
Sbjct: 23921 ASEPVVCKDPFDKPSQPGELEILSISKDSVTLQWEKPECDGGKEILGYWVEYRQSGDSAW 23980
Query: 1856 MKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRP---AQGVVTTL-ENVSPPRRA 1911
K + GL+ AT+YE V+A +T SRP A + T L +P R
Sbjct: 23981 KKSNKERIKDKQFTIGGLLEATEYEFRVFAENETGLSRPRRTAMSIKTKLTSGEAPGIRK 24040
Query: 1912 RVTDAT 1917
+ D T
Sbjct: 24041 EMKDVT 24046
Score = 99.8 bits (247), Expect = 3e-20
Identities = 244/1107 (22%), Positives = 422/1107 (38%), Gaps = 171/1107 (15%)
Query: 1092 PPYNTEVTET---TIVITWT-PAPRIGFKLGVRPSQGGEAPREV------TSDSGSIVVS 1141
P N EVTET + + W P G K+ + + R+ ++S V+
Sbjct: 6595 PVRNLEVTETFDGEVSLAWEEPLTDGGSKIIGYVVERRDIKRKTWVLATDRAESCEFTVT 6654
Query: 1142 GLTPG-VEYVYTIQVLR-----DGQERDAPIV--NKVVTPLSPPTNLHLEANPDTGVLTV 1193
GL G VEY++ + + E D P+ +K P PP N+ + GV ++
Sbjct: 6655 GLQKGGVEYLFRVSARNRVGTGEPVETDNPVEARSKYDVP-GPPLNVTITDVNRFGV-SL 6712
Query: 1194 SWERSTTP---DITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYT- 1249
+WE +IT Y I + ++ V A+ S T ++ G EY+ V
Sbjct: 6713 TWEPPEYDGGAEITNYVIELRDKTSIRWDTAM-TVRAEDLSATVTDVVEGQEYSFRVRAQ 6771
Query: 1250 --VKDDKES-----VPISDTIIPEVPQLTDLSFVDITDSSIGLRWTPL---NSSTIIGYR 1299
+ K S V ++D I P + +L+ D T SS+ L+W P S I+GY
Sbjct: 6772 NRIGVGKPSAATPFVKVADPIERPSPPV-NLTSSDQTQSSVQLKWEPPLKDGGSPILGYI 6830
Query: 1300 ITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLT------ 1353
I G+ I + Y VTGLE G Y V G S P+ +
Sbjct: 6831 IERCEEGKDNWIRCNMKLVPELTYKVTGLEKGNKYLYRVSAENKAGVSDPSEILGPLTAD 6890
Query: 1354 ----------------QQTAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVK 1397
+ VP P + + G TW + T V+ +K
Sbjct: 6891 DAFVEPTMDLSAFKDGLEVIVPNPITILVPSTGYPRPTATWCFGDKVLETGDRVK---MK 6947
Query: 1398 NEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHE-STPLRGRQKTGLDSPTGID 1456
AEL ISPS+ + L V ++S + + + P +P +
Sbjct: 6948 TLSAYAELVISPSERSDKGIYTLKLENRVKTISGEIDVNVIARP---------SAPKELK 6998
Query: 1457 FSDITANSFTVHWIAP----RATITGYRIRHHPEHFSGRPREDRVPHSRNSI--TLTNLT 1510
F DIT +S + W P + +TGY + + R +V + T+ +L
Sbjct: 6999 FGDITKDSVHLTWEPPDDDGGSPLTGYVVE---KREVSRKTWTKVMDFVTDLEFTVPDLV 7055
Query: 1511 PGTEYVVSIVALN-------GREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAP- 1562
G EY+ + A N + P+ + +TV D P +++ T S+ ++WD P
Sbjct: 7056 QGKEYLFKVCARNKCGPGEPAYVDEPVNMSTPATVPDPPENVKWRDRTANSIFLTWDPPK 7115
Query: 1563 ---AVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSP 1619
++ Y + G + V P +++ ++GL+ G Y V A+ +G
Sbjct: 7116 NDGGSRIKGYIVERCPRGSDKWV-ACGEPVAETKMEVTGLEEGKWYAYRVKALNRQG--- 7171
Query: 1620 ASSKPISINYRTEIDKPS-QMQVTDVQDNS---ISVKWLPSSSPVTGYRV----TTTPKN 1671
+SKP +P+ ++Q D Q+ + VK L + G ++ T T K
Sbjct: 7172 -ASKP---------SRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKP 7221
Query: 1672 GPGPTKTKT--AGPDQTEMTIEGL--QPTVEYVVS---------VYAQNPSGESQPLVQT 1718
P T TK +TIE + + TV V S + A N G + +V+
Sbjct: 7222 EPKITWTKADMILKQDKRITIENVPKKSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEV 7281
Query: 1719 AVTNIDR---PKGLAFTDVDVDSIKIAWESPQ----GQVSRYRVTYSSPEDGI-HELFPA 1770
V +D+ P TDV +S + W P+ +++ Y V + + + H+L +
Sbjct: 7282 NV--LDKPGPPAAFDITDVTNESCLLTWNPPRDDGGSKITNYVVERRATDSEVWHKL--S 7337
Query: 1771 PDGEEDTAELQGLRPGSEYTVSVVA-----LHDDMESQPLIGTQSTAIPA-PTDLKFTQV 1824
++ + L P EY V A + + +++ P+ P PT L+ + +
Sbjct: 7338 STVKDTNFKATKLIPNKEYIFRVAAENMYGVGEPVQASPITAKYQFDPPGPPTRLEPSDI 7397
Query: 1825 TPTSLSAQWTPPN----VQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYE 1880
T +++ W P+ +TGY V + ++ + ++ V GL KY
Sbjct: 7398 TKDAVTLTWCEPDDDGGSPITGYWVERLDPDTDKWVRCNKMPVKDTTYRVKGLTNKKKYR 7457
Query: 1881 VSVYALKDTLTSRPAQG-----VVTTLENVSPPRRARVTDATETTITISWRTKTE----- 1930
V A +P++ + ++ PP + V D +T++ ++W TK E
Sbjct: 7458 FRVLAENLAGPGKPSKSTEPILIKDPIDPPWPPGKPTVKDVGKTSVRLNW-TKPEHDGGA 7516
Query: 1931 TITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPV---- 1986
I + ++ + ++ + + GL G +Y + +N S P
Sbjct: 7517 KIESYVIEMLKTGTDEWVRVAEGVPTTQHLLPGLMEGQEYSFRVRAVNKAGESEPSEPSD 7576
Query: 1987 VIDASTAIDAPSNLRFLAT---TPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREVV 2039
+ + PS R+L T N+ + W P + IT YI++ + V
Sbjct: 7577 PVLCREKLYPPSPPRWLEVINITKNTADLKWTVPEKDGGSPITNYIVEKRDVRRKGWQTV 7636
Query: 2040 PRPRPGVTEATITGLEPGTEYTIYVIA 2066
T+ T+T L G+ Y V A
Sbjct: 7637 DTTVKD-TKCTVTPLTEGSLYVFRVAA 7662
Score = 99.8 bits (247), Expect = 3e-20
Identities = 292/1340 (21%), Positives = 474/1340 (35%), Gaps = 235/1340 (17%)
Query: 908 PSP-RDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTG 966
P P R+L+ V+V+ + T+ W PPE G + N E + + +T++ T
Sbjct: 11800 PGPVRNLKIVDVSSDRCTVCWDPPEDD-GGCEIQ----NYILEKCETKRMVWSTYS-ATV 11853
Query: 967 LSPGVT---------YYFKVFA-----VSHGRESKPLTAQQTTKLDA-----PTNLQFVN 1007
L+PG T Y F+V A ESKP+ A+ TK D P + V+
Sbjct: 11854 LTPGTTVTRLIEGNEYIFRVRAENKIGTGPPTESKPVIAK--TKYDKPGRPDPPEVTKVS 11911
Query: 1008 ETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSV---SKYPLRNLQPAS 1060
+ + TV+ W PP ITGY L + R V S + ++NL P
Sbjct: 11912 KEEMTVV--WNPPEYDGGKSITGYFLE--KKEKHSTRWVPVNKSAIPERRMKVQNLLPDH 11967
Query: 1061 EYTVSLVAIK----GNQESPKATGVF-TTLQPGSSIPPYNTEVTETT---IVITWTP--- 1109
EY + A G P V ++P PP N V +TT I + W
Sbjct: 11968 EYQFRVKAENEIGIGEPSLPSRPVVAKDPIEPPG--PPTNFRVVDTTKHSITLGWGKPVY 12025
Query: 1110 ---APRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPI 1166
AP IG+ + +RP +P D G + V +T+ L + QE + +
Sbjct: 12026 DGGAPIIGYVVEMRPKIADASP-----DEGWKRCNAAAQLVRKEFTVTSLDENQEYEFRV 12080
Query: 1167 VNKVVTPLSPPTNLHLEANP-----------DTGVLTVSWERSTTPD--ITGYRITTTPT 1213
+ + P L P D + + R+ P R P
Sbjct: 12081 CAQNQVGIGRPAELKEAIKPKEILEPPEIDLDASMRKLVIVRAGCPIRLFAIVRGRPAPK 12140
Query: 1214 NGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDD-------------KESVPIS 1260
+ ++ VV Q +L + + V + +DD +++V ++
Sbjct: 12141 VTWRKVGIDNVVRKGQV-----DLVDTMAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFVN 12195
Query: 1261 DTIIPEVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGYRIT--VVAAGEGIPIFEDFVDS 1318
++ ++DL D+T +S + W P + G ++T +V E V
Sbjct: 12196 VRVLDTPGPVSDLKVSDVTKTSCHVSWAPPENDG--GSQVTHYIVEKREADRKTWSTVTP 12253
Query: 1319 SV--GYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAV-------PPPTDLRFTNI 1369
V + VT L PG +Y V + G PT + + PP L T +
Sbjct: 12254 EVKKTSFHVTNLVPGNEYYFRVTAVNEYGPGVPTDVPKPVLASDPLSEPDPPRKLEVTEM 12313
Query: 1370 GPDTMRVTWAPP---PSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYV 1426
++ + W PP + ++ Y + D D ++V+T L G +Y
Sbjct: 12314 TKNSATLAWLPPLRDGGAKIDGYITSYREEEQPADRWTEYSVVKDLSLVVTGLKEGKKYK 12373
Query: 1427 VSVSSVYEQHESTPLRG----RQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIR 1482
V++ S P K L P + IT + G ++R
Sbjct: 12374 FRVAARNAVGVSLPREAEGVYEAKEQLLPPKILMPEQITIKA-------------GKKLR 12420
Query: 1483 HHPEHFSGRPR--------EDRV----------PHSRNSITLTNLTPGTEYVVSIVALNG 1524
H G+P ED V S + + + ++T S+ A N
Sbjct: 12421 IE-AHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGYYSLTAENS 12479
Query: 1525 ----REESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAP----AVTVRYYRITYGET 1576
++ +++ P D+ + A SL SW P + Y + +
Sbjct: 12480 SGTDTQKIKVVVMDAPGPPQPPFDISDIDADACSL--SWHIPLEDGGSNITNYIVEKCDV 12537
Query: 1577 GGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDS-PASSKPISINYRTEI-D 1634
V +K++ + L PG +Y V A G S P +S + + +
Sbjct: 12538 SRGDWVTAL-ASVTKTSCRVGKLIPGQEYIFRVRAENRFGISEPLTSPKMVAQFPFGVPS 12596
Query: 1635 KPSQMQVTDVQDNSISVKW-LPSS---SPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTI 1690
+P +VT V + I V W P S SP+ GY + +N K TE
Sbjct: 12597 EPKNARVTKVNKDCIFVAWDRPDSDGGSPIIGYLIERKERNSLLWVKANDTLVRSTEYPC 12656
Query: 1691 EGLQPTVEYVVSVYAQNPSGESQPL----VQTAVTNIDRPKGLAFTDVDVDSIKIAWESP 1746
GL +EY +YA N +G S P TA +D P DV ++ + W P
Sbjct: 12657 AGLVEGLEYSFRIYALNKAGSSPPSKPTEYVTARMPVDPPGKPEVIDVTKSTVSLIWARP 12716
Query: 1747 QGQVSRYRVTY-----SSPEDGIHELFPAP---DGEEDTAELQGLRPGSEYTVSVVALHD 1798
+ + Y P D AP EE TA GL ++Y +A
Sbjct: 12717 KHDGGSKIIGYFVEACKLPGDKWVRCNTAPHQIPQEEYTA--TGLEEKAQYQFRAIARTA 12774
Query: 1799 DMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLT-GYRVRVTPKEKTG--- 1854
S P P+D P ++ A+ PP + L+ + +T K T
Sbjct: 12775 VNISPP---------SEPSD-------PVTILAENVPPRIDLSVAMKSLLTVKAGTNVCL 12818
Query: 1855 -------PMKEINLAPDSSSV-VVSGLMVATKYEVSVYAL-----KD----TLTSRPAQG 1897
PM ++ D + + G+ +A + + L KD T+T+ + G
Sbjct: 12819 DATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTITAENSSG 12878
Query: 1898 ------VVTTLENVSPPRRARVTDATETTITISWRTKTE----TITGFQVDAVPANGQTP 1947
+ L+ PP ++ +SW E IT + VD +
Sbjct: 12879 SKSATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYIVDKRETSRPNW 12938
Query: 1948 IQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVID---ASTAIDAPSNLR--- 2001
Q + + S ++ L G +Y+ + N PV + A D P
Sbjct: 12939 AQVSATVPITSCSVEKLIEGHEYQFRICAENKYGVGDPVFTEPAIAKNPYDPPGRCDPPV 12998
Query: 2002 FLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREVVPRPRPGVTEATI--TGLE 2055
T + + VSW+PP + ITGY++ EK + R + E T+ TGL+
Sbjct: 12999 ISNITKDHMTVSWKPPADDGGSPITGYLL--EKRETQAVNWTKVNRKPIIERTLKATGLQ 13056
Query: 2056 PGTEYTIYVIALKNNQKSEP 2075
GTEY V A+ +P
Sbjct: 13057 EGTEYEFRVTAINKAGPGKP 13076
Score = 98.6 bits (244), Expect = 7e-20
Identities = 157/730 (21%), Positives = 276/730 (37%), Gaps = 78/730 (10%)
Query: 785 KYIVNVYQISEDGEQSLIL-----STSQTTAP---DAPPDPT----VDQVDDTSIVVRWS 832
K + I + GE +L L +TS+T D P PT +D++D TSI + W
Sbjct: 23298 KLTIRETTIRDTGEYTLELKNVTGTTSETIKVIILDKPGPPTGPIKIDEIDATSITISWE 23357
Query: 833 RPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQE 888
P+ AP++GY + + ++ T ++ + L G +Y + A N+
Sbjct: 23358 PPELDGGAPLSGYVVEQRDAHRPGWLPVSESVTRSTFKFTRLTEGNEYVFRVAAT--NRF 23415
Query: 889 STPVVIQQETTGTPRSDTVPSPRD-LQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIP 943
+Q E S +P P + LQ +V+ +T+ W PPE S VTGY V+
Sbjct: 23416 GIGSYLQSEVIECRSSIRIPGPPETLQIFDVSRDGMTLTWYPPEDDGGSQVTGYIVERKE 23475
Query: 944 VNLPG-EHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSH------GRESKPLTAQQTTK 996
V ++P++ + TGL+ G+ Y +V A++ R SKP+ A
Sbjct: 23476 VRADRWVRVNKVPVTMTRYRS-TGLTEGLEYEHRVTAINARGSGKPSRPSKPIVAMDPIA 23534
Query: 997 LDA-PTNLQFVNETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPS-VSK 1050
P N + + T ++V + W+ P +++TGY + + + + + N P+ + +
Sbjct: 23535 PPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTKCNTTPTKIRE 23594
Query: 1051 YPLRNLQPASEYTVSLVAIK-GNQESPKATGVFTTLQPGSSIPPYNTE--------VTET 1101
Y L +L +EY ++A G P + P Y + V +
Sbjct: 23595 YTLTHLPQGAEYRFRVLACNAGGPGEPAEVPGTVKVTEMLEYPDYELDERYQEGIFVRQG 23654
Query: 1102 TIVITWTPAPRIGFKLGVRPSQGGEAPREV---TSDSGS-IVVSGLTPGVEYVYTIQVLR 1157
++ P F + +G + + TS++ + +V+ G Y + +
Sbjct: 23655 GVIRLTIPIKGKPFPICKWTKEGQDISKRAMIATSETHTELVIKEADRGDSGTYDLVLEN 23714
Query: 1158 DGQERDAPIVNKVV-TPLSPPTNLHLEANPDTGVLTVSWERSTTP---DITGYRITTTPT 1213
++ I +V+ +P SP L + + + VSW DI GY +
Sbjct: 23715 KCGKKAVYIKVRVIGSPNSPEGPLEYD-DIQVRSVRVSWRPPADDGGADILGYILERREV 23773
Query: 1214 NGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKD--------DKESVPISDTIIP 1265
+++ V +S L +EY+ V +E V + P
Sbjct: 23774 PKAAWYTIDSRVRG--TSLVVKGLKENVEYHFRVSAENQFGISKPLKSEEPVTPKTPLNP 23831
Query: 1266 EVPQLTDLSFVDITDSSIGLRWT---PLNSSTIIGYRITVVAAGEGIPIFEDFVDSSVGY 1322
P +D+T SS+ L W+ S + GY I + + +
Sbjct: 23832 PEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRVTGYYIERKETSTDKWVRHNKTQITTTM 23891
Query: 1323 YTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAVPPPTD-------LRFTNIGPDTMR 1375
YTVTGL P +Y +I + G S + ++ P D L +I D++
Sbjct: 23892 YTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCKDPFDKPSQPGELEILSISKDSVT 23951
Query: 1376 VTWAPPP---SIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSV 1432
+ W P ++ + V Y + D + LL TEY V +
Sbjct: 23952 LQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERIKDKQFTIGGLLEATEYEFRVFAE 24011
Query: 1433 YEQHESTPLR 1442
E S P R
Sbjct: 24012 NETGLSRPRR 24021
Score = 96.3 bits (238), Expect = 3e-19
Identities = 294/1454 (20%), Positives = 518/1454 (35%), Gaps = 209/1454 (14%)
Query: 684 IQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSA 743
I+ G Q + + + S P+T + P PL VT +TA ++W
Sbjct: 18275 IRTDGGQYILKLSNVGGTKSIPITVKVLDRPGPPEGPL-----KVTGVTAEKCYLAWNPP 18329
Query: 744 SDTVSGFRVEYELSEEGDEPQYLDLPSTATSVN-----IPDLLPGRKYI-----VNVYQI 793
G + + + E+ E L +T V + LLPG +YI VN Y I
Sbjct: 18330 LQD-GGANISHYIIEKR-ETSRLSWTQVSTEVQALNYKVTKLLPGNEYIFRVMAVNKYGI 18387
Query: 794 SEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRP----QAPITGYRIVYSPSV 849
E E + + + P P P V + S+VV W+RP I GY I+
Sbjct: 18388 GEPLESGPVTACNPYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGY-ILEKRDK 18446
Query: 850 EGSSTELNLPETANSVTL--SDLQPGVQYNITIYAVEE---NQESTPVVIQQETTGTPRS 904
EG +T + L + L G Y + A + S P V +
Sbjct: 18447 EGVRWTKCNKKTLTDLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYR------AC 18500
Query: 905 DTVPSPRDLQFVEVTDV---KVTIMWTPP----ESAVTGYRVDV------------IPVN 945
D + P +VTD V++ W+ P + V GY V+V P
Sbjct: 18501 DALYPPGPPSNPKVTDTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAADEWTTCTPPTG 18560
Query: 946 LPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLT------AQQ-----T 994
L G+ VT L Y F++ A++ +P T AQ+
Sbjct: 18561 LQGKQ-----------FTVTKLKENTEYNFRICAINSEGVGEPATLPGSVVAQERIEPPE 18609
Query: 995 TKLDAPTNLQFVNETDSTVLVRWT---PPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKY 1051
+LDA V +T+ + T P ++ + LT R Q V S +
Sbjct: 18610 IELDADLRKVVVLRASATLRLFVTIKGRPEPEVKWEKAEGILTDRA---QIEVTSSFTML 18666
Query: 1052 PLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAP 1111
+ N+ +L + V P + + EV + ++ ++W P
Sbjct: 18667 VIDNVTRFDSGRYNLTLENNSGSKTAFVNVRVLDSPSAPVNLTIREVKKDSVTLSWEPPL 18726
Query: 1112 RIGFKLGVRPSQGGEAPREVTSDSGSIV----------VSGLTPGVEYVYTIQVLRD--- 1158
G G + + RE T + + + + L G Y + + +
Sbjct: 18727 IDG---GAKITNYIVEKRETTRKAYATITNNCTKTTFRIENLQEGCSYYFRVLASNEYGI 18783
Query: 1159 GQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT---PDITGYRITTTPTNG 1215
G + KV P PP + L + T+ WE+ + ITGY +
Sbjct: 18784 GLPAETTEPVKVSEPPLPPGRVTL-VDVTRNTATIKWEKPESDGGSKITGYVVEMQTKGS 18842
Query: 1216 QQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPEVPQLTDLSF 1275
++ ++ +V + T L+ G EY V V + S P +P + + ++
Sbjct: 18843 EKWSTCTQVKTLE---ATISGLTAGEEYVFRVAAVNEKGRSDP-RQLGVPVIARDIEIK- 18897
Query: 1276 VDITDSSIGLRWTPLNSSTIIGYRITVVAAG----------EGIPIFEDFVDSSVGYYTV 1325
S+ L + N +I V G +G + E + TV
Sbjct: 18898 -----PSVELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTV 18952
Query: 1326 TGL--EPGIDYDISVITLI----NGGESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTWA 1379
T L + D+ L G + P T+ PP +R + D++ ++W
Sbjct: 18953 TSLSIKEASKEDVGTYELCVSNSAGSITVPITIIVLDRPGPPGPIRIDEVSCDSITISWN 19012
Query: 1380 PPP---SIDLTNFLVRYSPVKNEEDVAE---LSISPSDNAVVLTNLLPGTEYVVSVSS-- 1431
PP ++N++V K E +S + + ++ + L G+EY V +
Sbjct: 19013 PPEYDGGCQISNYIVE----KKETTSTTWHIVSQAVARTSIKIVRLTTGSEYQFRVCAEN 19068
Query: 1432 ---VYEQHESTPLRGRQKTGLDSPTGI-DFSDITANSFTVHWIAP----RATITGYRIRH 1483
ES+ + P G T ++ V W P + + GY + +
Sbjct: 19069 RYGKSSYSESSAVVAEYPFSPPGPPGTPKVVHATKSTMLVTWQVPVNDGGSRVIGYHLEY 19128
Query: 1484 HPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN----GREESPLLIGQQSTVS 1539
+ +++ + + ++ L G Y + A N G+
Sbjct: 19129 KERSSILWSKANKILIADTQMKVSGLDEGLMYEYRVYAENIAGIGKCSKSCEPVPARDPC 19188
Query: 1540 DVPRDLEVVAATPTSLLISWDAP----AVTVRYYRITYGETGGNSPVQEFTVPGSKSTAT 1595
D P EV T S+ + W P + Y + E ++ ++
Sbjct: 19189 DPPGQPEVTNITRKSVSLKWSKPHYDGGAKITGYIVERRELPDGRWLKCNYTNIQETYFE 19248
Query: 1596 ISGLKPGVDYTITVYAVTGRGD-SPASSKPISINYRTEIDKPSQMQVTDVQDNSI--SVK 1652
++ L Y V+A S S I + +++ P M +D + + +
Sbjct: 19249 VTELTEDQRYEFRVFARNAADSVSEPSESTGPIIVKDDVEPPRVMMDVKFRDVIVVKAGE 19308
Query: 1653 WLPSSSPVTG--YRVTTTPKNG---PGPTKTKTAGPD-QTEMTIEGL--QPTVEYVVSVY 1704
L ++ + G V + K+G +T+ D T +T++ + T +YV+++
Sbjct: 19309 VLKINADIAGRPLPVISWAKDGIEIEERARTEIISTDNHTLLTVKDCIRRDTGQYVLTL- 19367
Query: 1705 AQNPSGESQPLVQTAVTNIDRPKG--LAFTDVDVDSIKIAWESPQ----GQVSRYRVTYS 1758
+N +G V V + P L + + ++W PQ + Y V
Sbjct: 19368 -KNVAGTRSVAVNCKVLDKPGPPAGPLEINGLTAEKCSLSWGRPQEDGGADIDYYIV--- 19423
Query: 1759 SPEDGIHELFPAPDGE--EDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPA- 1815
+ H + +GE + ++ L G+EY V ++ +PL +S AI A
Sbjct: 19424 EKRETSHLAWTICEGELQMTSCKVTKLLKGNEYIFRVTGVNKYGVGEPL---ESVAIKAL 19480
Query: 1816 --------PTDLKFTQVTPTSLSAQWTPP----NVQLTGYRVRVTPKEKTGPMKEINLAP 1863
PT L+ T VT S++ W+ P +++GY + K ++
Sbjct: 19481 DPFTVPSPPTSLEITSVTKESMTLCWSRPESDGGSEISGYIIERREKNSLRWVRVNKKPV 19540
Query: 1864 DSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQ--GVVTTLENV---SPPRRARVTDATE 1918
V +GL +YE VYA S P++ ++ + V SPP + ++ D+ +
Sbjct: 19541 YDLRVKSTGLREGCEYEYRVYAENAAGLSLPSETSPLIRAEDPVFLPSPPSKPKIVDSGK 19600
Query: 1919 TTITISWRTKT----ETITGFQVD---AVPANGQTPIQRTIKPDVRSYTITGLQPGTDYK 1971
TTITI+W ITG+ V+ + + +T IQ + YTI+GL G +Y
Sbjct: 19601 TTITIAWVKPLFDGGAPITGYTVEYKKSDDTDWKTSIQSLRGTE---YTISGLTTGAEYV 19657
Query: 1972 IYLYTLNDNARSSP 1985
+ ++N S P
Sbjct: 19658 FRVKSVNKVGASDP 19671
Score = 95.5 bits (236), Expect = 6e-19
Identities = 319/1473 (21%), Positives = 540/1473 (36%), Gaps = 232/1473 (15%)
Query: 777 IPDLLPGRKYIVNVYQISEDG--EQSLILSTSQTTAPDAPPD------PTVDQVDDTSIV 828
+ DL+ G +Y V ++ G + S + PD PP V++ + +IV
Sbjct: 9581 VEDLVEGGEYEFRVKAVNAAGVSKPSATVGPCDCQRPDMPPSIDLKEFMEVEEGTNVNIV 9640
Query: 829 VR----------WSR--PQAPITGYRIVYSPSVE----GSSTELNLPETANSVTLSDLQP 872
+ W + P+ P ++Y V + L +P++ S T
Sbjct: 9641 AKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDT------ 9694
Query: 873 GVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE- 931
G+ TI AV N + ++ G P P ++F V+ ++T+ W PP+
Sbjct: 9695 GLY---TITAVN-NLGTASKEMRLNVLGRPGPPVGP----IKFESVSADQMTLSWFPPKD 9746
Query: 932 ---SAVTGYRVDVIPVNLPG-EHGQRLPISRNTFAEVTGLSPGVTYYFKVFA-----VSH 982
S +T Y ++ N H P + + L G Y F++ A +
Sbjct: 9747 DGGSKITNYVIEKREANRKTWVHVSSEP--KECTYTIPKLLEGHEYVFRIMAQNKYGIGE 9804
Query: 983 GRESKPLTAQQTTKLD-APTNLQFVNETDSTVLVRWTPPR----AQITGYRLTVGLTRRG 1037
+S+P TA+ + AP + T +++ V W P + +TGY L + T
Sbjct: 9805 PLDSEPETARNLFSVPGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPVTGYWLEMKDTTSK 9864
Query: 1038 QPRQYNVGPSVS-----KYPLRNLQPASEYTVSLVAIKGNQESPK------ATGVFTTLQ 1086
+ ++ N P + Y + L S+Y + AI P AT
Sbjct: 9865 RWKRVNRDPIKAMTLGVSYKVTGLIEGSDYQFRVYAINAAGVGPASLPSDPATARDPIAP 9924
Query: 1087 PGSSIPPYNTEVTETTIVITWTPAPRIGFKLG----VRPSQGGEAPREVTSDSG----SI 1138
PG P T+ T+++ + W+P + G V + G+ E D +
Sbjct: 9925 PGPPFPKV-TDWTKSSADLEWSPPLKDGGSKVTGYIVEYKEEGKEEWEKGKDKEVRGTKL 9983
Query: 1139 VVSGLTPGVEYVYTIQVLRD---GQERDAPIVNKVVTPLSPPTNLHLEANP-DTGVLTVS 1194
VV+GL G Y + ++ + G+ + V ++ L P +L L+A+ D V+
Sbjct: 9984 VVTGLKEGAFYKFRVRAVNIAGIGEPGEVTDVIEMKDRLVSP-DLQLDASVRDRIVVHAG 10042
Query: 1195 WERSTTPDITGYRITTTPTNGQQGNSLEEVV---HADQSSCTFDNLSPGLEYNVSVYTVK 1251
++G T N + +E A SS N + VY++
Sbjct: 10043 GVIRIIAYVSGKPPPTVTWNMNERTLPQEATIETTAISSSMVIKNCQRSHQ---GVYSLL 10099
Query: 1252 DDKESVPISDTIIPEV-----PQLTDLSFVDITDSSIGLRW-TPLNS--STIIGYRITVV 1303
E+ TII +V P T ++T+ S L W +P + S I Y I
Sbjct: 10100 AKNEAGERKKTIIVDVLDVPGPVGTPFLAHNLTNESCKLTWFSPEDDGGSPITNYVIEKR 10159
Query: 1304 AAGEGI--PIFEDFVDSSVGYYTVTGLEPGIDY--DISVITLINGGESAPTT----LTQQ 1355
+ P+ + TV GL G Y I+ I G T+ + +
Sbjct: 10160 ESDRRAWTPVTYTVTRQNA---TVQGLIQGKAYFFRIAAENSIGMGPFVETSEALVIREP 10216
Query: 1356 TAVPP-PTDLRFTNIGPDTMRVTWAPPP---SIDLTNFLVRYSPVKNEEDVAELSISPSD 1411
VP P DL + +T+ +TW PP ++ N+++ + E+ + +
Sbjct: 10217 ITVPERPEDLEVKEVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEKFHKVTNDNLLS 10276
Query: 1412 NAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQ----KTGLDSPT-GIDFSDITANSFT 1466
+ L G Y VS+V + P + K L PT +DF D T
Sbjct: 10277 RKYTVKGLKEGDTYEYRVSAVNIVGQGKPSFCTKPITCKDELAPPTLHLDFRD----KLT 10332
Query: 1467 VHWIAPRATITGYRIRHHPEHFSGRPR------EDRVPHSRNSITLTNLTPGTEYVVSIV 1520
+ + +TG +SG+P+ +D + T TP T + I
Sbjct: 10333 IR-VGEAFALTG--------RYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATLALEKIK 10383
Query: 1521 ALNGREESPLLIGQQST--------VSDVPRDLEVVA------ATPTSLLISWDAP---- 1562
A ++ + ST V+ V R V T ++ISW P
Sbjct: 10384 AKRSDSGKYCVVVENSTGSRKGFCQVNVVDRPGPPVGPVSFDEVTKDYMVISWKPPLDDG 10443
Query: 1563 AVTVRYYRITYGETGGN--SPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDS-P 1619
+ Y I E G + PV T +K+T +S L G DY ++A G S P
Sbjct: 10444 GSKITNYIIEKKEVGKDVWMPV---TSASAKTTCKVSKLLEGKDYIFRIHAENLYGISDP 10500
Query: 1620 ASSKPISINYRTEI-DKPSQMQVTDVQDNSISVKWLP---SSSPVTGY---RVTTTPKNG 1672
S + R + D P Q VT+V +S V W P+T Y + T K
Sbjct: 10501 LVSDSMKAKDRFRVPDAPDQPIVTEVTKDSALVTWNKPHDGGKPITNYILEKRETMSKRW 10560
Query: 1673 PGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQN------PSGESQPL-VQTAVTNIDR 1725
TK T+ + L +Y V A+N PS S+P+ + +
Sbjct: 10561 ARVTKDPIH--PYTKFRVPDLLEGCQYEFRVSAENEIGIGDPSPPSKPVFAKDPIAKPSP 10618
Query: 1726 PKGLAFTDVDVDSIKIAWESPQ----GQVSRYRVTYSSPEDGI-HELFPAPDGEEDTA-E 1779
P D +S+ + W+ P+ ++ Y V Y D P+ +T +
Sbjct: 10619 PVNPEAIDTTCNSVDLTWQPPRHDGGSKILGYIVEYQKVGDEEWRRANHTPESCPETKYK 10678
Query: 1780 LQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTS-LSAQWTPPNV 1838
+ GLR G Y V+A++ ES P +P P +K P L A
Sbjct: 10679 VTGLRDGQTYKFRVLAVNAAGESDP------AHVPEPVLVKDRLEPPELILDANMAREQH 10732
Query: 1839 QLTGYRVRVT------PKEKTGPMKEINLAPDSSSVVVSGLMVATKYEV--------SVY 1884
G +R++ P K KE AP + + V+ V +K E+ +Y
Sbjct: 10733 IKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARIDVTP--VGSKLEIRNAAHEDGGIY 10790
Query: 1885 AL--KDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTE----TITGFQVD 1938
+L ++ S+ V L+ PPR V++ + + ++W+ + IT + V+
Sbjct: 10791 SLTVENPAGSKTVSVKVLVLDKPGPPRDLEVSEIRKDSCYLTWKEPLDDGGSVITNYVVE 10850
Query: 1939 A--VPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPV-------VID 1989
V + +P+ T K +S+ L G Y + N R V +D
Sbjct: 10851 RRDVASAQWSPLSATSKK--KSHFAKHLNEGNQYLFRVAAENQYGRGPFVETPKPIKALD 10908
Query: 1990 ASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREVVPRPRPG 2045
P +L + + + W P + ITGY+++Y++ G+ ++ +
Sbjct: 10909 PLHPPGPPKDLHHVDVDKTEVSLVWNKPDRDGGSPITGYLVEYQEEGT--QDWIKFKTVT 10966
Query: 2046 VTEATITGLEPGTEYTIYVIALKNNQKSEPLIG 2078
E +TGL+ G Y V K+E ++G
Sbjct: 10967 NLECVVTGLQQGKTYRFRV-------KAENIVG 10992
Score = 95.1 bits (235), Expect = 7e-19
Identities = 312/1572 (19%), Positives = 569/1572 (36%), Gaps = 228/1572 (14%)
Query: 616 ITETPSQPNSHPIQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLK 672
+T T S + W P+ S + Y++ +PK + +W N+ + GL
Sbjct: 17722 VTLTDVSQTSASLMWEKPEHDGGSRVLGYVVEMQPKGTE-KWSIVAESKVCNA-VVTGLS 17779
Query: 673 PGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETT---PFSP--LVATSES 727
G Y+ ++ + + G + PV + +T + + PF+ + A +
Sbjct: 17780 SGQEYQFRVKAYNEKGKSD-------PRVLGVPVIAKDLTIQPSLKLPFNTYSIQAGEDL 17832
Query: 728 VTEITASSFV---VSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGR 784
EI +SWV + + + +++ TATS + + G
Sbjct: 17833 KIEIPVIGRPRPNISWVKDGEPLK-------------QTTRVNVEETATST-VLHIKEGN 17878
Query: 785 KYIVNVYQISED---GEQSLILSTSQTTAPDAPPDPT-VDQVDDTSIVVRWSRPQ----A 836
K Y ++ G + LS P P P D+V +V+ W P
Sbjct: 17879 KDDFGKYTVTATNSAGTATENLSVIVLEKPGPPVGPVRFDEVSADFVVISWEPPAYTGGC 17938
Query: 837 PITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQ 896
I+ Y + + + ++ ++ ++ L+ G +Y I+A +S P+ +
Sbjct: 17939 QISNYIVEKRDTTTTTWHMVSATVARTTIKITKLKTGTEYQFRIFAENRYGKSAPLDSKA 17998
Query: 897 ETTGTPRSDTVPSPRDLQFV-EVTDVKVTIMWTPPES----AVTGYRVDVIPVN-LPGEH 950
P + P P FV ++ ++ + W P + + GY ++ N +
Sbjct: 17999 VIVQYPFKE--PGPPGTPFVTSISKDQMLVQWHEPVNDGGTKIIGYHLEQKEKNSILWVK 18056
Query: 951 GQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQT----TKLDAPTNLQFV 1006
+ PI F + TGL G+ Y FKV A + KP + D P + +
Sbjct: 18057 LNKTPIQDTKF-KTTGLDEGLEYEFKVSAENIVGIGKPSKVSECFVARDPCDPPGRPEAI 18115
Query: 1007 NETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSV-SKYPLRNLQPASE 1061
T + V ++W P ++ITGY + G+ + + + +++ + L
Sbjct: 18116 VITRNNVTLKWKKPAYDGGSKITGYIVEKKDLPDGRWMKASFTNVLETEFTVSGLVEDQR 18175
Query: 1062 YTVSLVA--IKGNQESPK-ATGVFTTLQ----PGSSIPPYNTEVT-----ETTIV---IT 1106
Y ++A GN P ++G T P +S+ P +V ET ++ I
Sbjct: 18176 YEFRVIARNAAGNFSEPSDSSGAITARDEIDAPNASLDPKYKDVIVVHAGETFVLEADIR 18235
Query: 1107 WTPAPRIGFKLGVRPSQGGEAPREVTS--DSGSIVVSGL--TPGVEYVYTIQVLRDGQER 1162
P P + + + + A E+ S ++VV T G +Y+ +++ G +
Sbjct: 18236 GKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQYI--LKLSNVGGTK 18293
Query: 1163 DAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWE---RSTTPDITGYRITTTPTNGQQGN 1219
PI KV+ PP ++W + +I+ Y I T+
Sbjct: 18294 SIPITVKVLDRPGPPEGPLKVTGVTAEKCYLAWNPPLQDGGANISHYIIEKRETSRLSWT 18353
Query: 1220 SLEEVVHADQSSCTFDNLSPGLEY-----NVSVYTVKDDKESVPIS---------DTIIP 1265
+ V A T L PG EY V+ Y + + ES P++ P
Sbjct: 18354 QVSTEVQALNYKVT--KLLPGNEYIFRVMAVNKYGIGEPLESGPVTACNPYKPPGPPSTP 18411
Query: 1266 EVPQLTDLSFV-----DITDSSI-------------GLRWTPLNSSTIIGYRITVVAAGE 1307
EV +T S V + D G+RWT N T+ R+ V E
Sbjct: 18412 EVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDKEGVRWTKCNKKTLTDLRLRVTGLTE 18471
Query: 1308 GIPI-FEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAVPPPTDLRF 1366
G F +++ G + EP + Y G PP++ +
Sbjct: 18472 GHSYEFRVAAENAAGVGEPS--EPSVFYRACDALYPPG---------------PPSNPKV 18514
Query: 1367 TNIGPDTMRVTWAPP---PSIDLTNFLVRYSPVKNEE-DVAELSISPSDNAVVLTNLLPG 1422
T+ ++ + W+ P + ++V +E +T L
Sbjct: 18515 TDTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAADEWTTCTPPTGLQGKQFTVTKLKEN 18574
Query: 1423 TEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGY-RI 1481
TEY + ++ + P ++ A+ V + AT+ + I
Sbjct: 18575 TEYNFRICAINSEGVGEPATLPGSVVAQERIEPPEIELDADLRKVVVLRASATLRLFVTI 18634
Query: 1482 RHHPEHFSGRPREDRVPHSRNSITLT---------NLTPGTEYVVSIVALNGREESPLLI 1532
+ PE + + + R I +T N+T ++ N +
Sbjct: 18635 KGRPEPEVKWEKAEGILTDRAQIEVTSSFTMLVIDNVTRFDSGRYNLTLENNSGSKTAFV 18694
Query: 1533 GQQSTVS-DVPRDLEVVAATPTSLLISWDAPAVT----VRYYRITYGETGGNSPVQEFTV 1587
+ S P +L + S+ +SW+ P + + Y + ET + T
Sbjct: 18695 NVRVLDSPSAPVNLTIREVKKDSVTLSWEPPLIDGGAKITNYIVEKRETTRKA-YATITN 18753
Query: 1588 PGSKSTATISGLKPGVDYTITVYAVT--GRGDSPASSKPISINYRTEIDKPSQMQVTDVQ 1645
+K+T I L+ G Y V A G G +++P+ ++ P ++ + DV
Sbjct: 18754 NCTKTTFRIENLQEGCSYYFRVLASNEYGIGLPAETTEPVKVSEPPL--PPGRVTLVDVT 18811
Query: 1646 DNSISVKW-LPSS---SPVTGYRVTTTPKNGPGPTKTKTAGPDQT-EMTIEGLQPTVEYV 1700
N+ ++KW P S S +TGY V K G K T +T E TI GL EYV
Sbjct: 18812 RNTATIKWEKPESDGGSKITGYVVEMQTK---GSEKWSTCTQVKTLEATISGLTAGEEYV 18868
Query: 1701 VSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVD-SIKIAWESPQGQVSRYRVTYSS 1759
V A N G S P Q V I R D+++ S+++ + + + +R ++
Sbjct: 18869 FRVAAVNEKGRSDPR-QLGVPVIAR-------DIEIKPSVELPFHTFNVK-AREQLKIDV 18919
Query: 1760 PEDGIHELFP--APDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQ-------- 1809
P G + DG+ E + S TV+ +++ + S+ +GT
Sbjct: 18920 PFKGRPQATVNWRKDGQT-LKETTRVNVSSSKTVTSLSIKE--ASKEDVGTYELCVSNSA 18976
Query: 1810 -STAIPA----------PTDLKFTQVTPTSLSAQWTPPNV----QLTGYRVRVTPKEKTG 1854
S +P P ++ +V+ S++ W PP Q++ Y V KE T
Sbjct: 18977 GSITVPITIIVLDRPGPPGPIRIDEVSCDSITISWNPPEYDGGCQISNYIVE--KKETTS 19034
Query: 1855 PMKEI-NLAPDSSSVVVSGLMVATKYEVSVYAL----KDTLTSRPAQGVVTTLENVSPPR 1909
I + A +S+ + L ++Y+ V A K + + A PP
Sbjct: 19035 TTWHIVSQAVARTSIKIVRLTTGSEYQFRVCAENRYGKSSYSESSAVVAEYPFSPPGPPG 19094
Query: 1910 RARVTDATETTITISWRTKT----ETITGFQVDAVPANG--QTPIQRTIKPDVRSYTITG 1963
+V AT++T+ ++W+ + G+ ++ + + + + D + ++G
Sbjct: 19095 TPKVVHATKSTMLVTWQVPVNDGGSRVIGYHLEYKERSSILWSKANKILIADTQ-MKVSG 19153
Query: 1964 LQPGTDYKIYLYTLN----DNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPR- 2018
L G Y+ +Y N S + A D P T S+ + W P
Sbjct: 19154 LDEGLMYEYRVYAENIAGIGKCSKSCEPVPARDPCDPPGQPEVTNITRKSVSLKWSKPHY 19213
Query: 2019 ---ARITGYIIK 2027
A+ITGYI++
Sbjct: 19214 DGGAKITGYIVE 19225
Score = 94.7 bits (234), Expect = 1e-18
Identities = 315/1607 (19%), Positives = 572/1607 (35%), Gaps = 282/1607 (17%)
Query: 628 IQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISI 684
+ W P+ + I Y++ K W + + GL G Y ++ ++
Sbjct: 7505 LNWTKPEHDGGAKIESYVIEML-KTGTDEWVRVAEGVPTTQHLLPGLMEGQEYSFRVRAV 7563
Query: 685 QQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSAS 744
+ G E + S+ V + P V IT ++ + W +
Sbjct: 7564 NKAGESEPSE------------PSDPVLCREKLYPPSPPRWLEVINITKNTADLKW-TVP 7610
Query: 745 DTVSGFRVEYELSEEGDEP----QYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGE-- 798
+ G + + E+ D Q +D T + L G Y+ V + G+
Sbjct: 7611 EKDGGSPITNYIVEKRDVRRKGWQTVDTTVKDTKCTVTPLTEGSLYVFRVAAENAIGQSD 7670
Query: 799 ----QSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ----APITGYRIVYSPSVE 850
+ +L+ T P P V V + ++W P+ PI Y I +
Sbjct: 7671 YTEIEDSVLAKDTFTTPGPPYALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKERL- 7729
Query: 851 GSSTELNLPETAN---SVTLSDLQPGVQYNITIYAVEEN-----QESTPVVIQQETTGTP 902
+ + +TA + ++D+ G + + A E E T ++ ++ T P
Sbjct: 7730 -GTRWVKAGKTAGPDCNFRVTDVIEGTEVQFQVRAENEAGVGHPSEPTEILSIEDPTSPP 7788
Query: 903 RSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPVNLPGEHGQRL---P 955
P DL + + I W PPE S + GY V++ PV E R+ P
Sbjct: 7789 SP-----PLDLHVTDAGRKHIAIAWKPPEKNGGSPIIGYHVEMCPVGT--EKWMRVNSRP 7841
Query: 956 ISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLV 1015
I F G+ P Y +V AV+ S+P + P ++ ++V
Sbjct: 7842 IKDLKFKVEEGVVPDKEYVLRVRAVNAIGVSEPSEISENVVAKDPDCKPTIDLETHDIIV 7901
Query: 1016 RWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPL-RNLQPASEYTVSLVAIKGNQE 1074
I G +L++ + R P P+VS + + ++ + T+ I + E
Sbjct: 7902 --------IEGEKLSIPVPFRAVPV-----PTVSWHKDGKEVKASDRLTMKNDHISAHLE 7948
Query: 1075 SPKAT----GVFT-TLQP--GSSIPPYN---------------TEVTETTIVITWTP--- 1109
PK+ G++T TL+ GS+ N +++T+++ +TW P
Sbjct: 7949 VPKSVRADAGIYTITLENKLGSATASINVKVIGLPGPCKDIKASDITKSSCKLTWEPPEF 8008
Query: 1110 ---APRIGFKLGVRPSQGGEAPREVTSDSGSI--VVSGLTPGVEYVYTIQVLRD-GQERD 1163
P + + L R + G V S + V L P EY + ++ + G
Sbjct: 8009 DGGTPILHYVLERREA-GRRTYIPVMSGENKLSWTVKDLIPNGEYFFRVKAVNKVGGGEY 8067
Query: 1164 APIVNKVVT-----PLSPPTNLHLEANPDTGVLTVSWERSTTPD---ITGYRITTTPTNG 1215
+ N V+ P PP ++ + NP +T++W+ I GY I
Sbjct: 8068 IELKNPVIAQDPKQPPDPPVDVEVH-NPTAEAMTITWKPPLYDGGSKIMGYIIEKIAKGE 8126
Query: 1216 QQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYT-----VKDDKESVPISDTIIP-EVPQ 1269
++ E + + T L G EY V + + + P + + P + P+
Sbjct: 8127 ERWKRCNEHL-VPILTYTAKGLEEGKEYQFRVRAENAAGISEPSRATPPTKAVDPIDAPK 8185
Query: 1270 LTDLSFVDIT-------DSSIG------LRWTPLNSSTIIGYRITVVAA-------GEGI 1309
+ + +++ D+SI + W + + I+ I AA GE +
Sbjct: 8186 VILRTSLEVKRGDEIALDASISGSPYPTITWIK-DENVIVPEEIKKRAAPLVRRRKGE-V 8243
Query: 1310 PIFEDFVDSSVGYYTVTGLEPGI-----------DYDISVITLIN--GGESAPTTLTQQT 1356
E FV ++ + G D+ + +I + N G AP T++
Sbjct: 8244 QEEEPFVLPLTQRLSIDNSKKGESQLRVRDSLRPDHGLYMIKVENDHGIAKAPCTVSVLD 8303
Query: 1357 AVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVL 1416
PP + F +I ++ W PP D + ++ Y+ K ++ P +V+
Sbjct: 8304 TPGPPINFVFEDIRKTSVLCKWEPPLD-DGGSEIINYTLEKKDK------TKPDSEWIVV 8356
Query: 1417 TNLLPGTEYVVSVSSVYEQHE------------------STPLRGRQKTG-LDSPTGIDF 1457
T+ L +Y SV+ + E E S PL + G D+P
Sbjct: 8357 TSTLRHCKY--SVTKLIEGKEYLFRVRAENRFGPGPPCVSKPLVAKDPFGPPDAPDKPIV 8414
Query: 1458 SDITANSFTVHWIAPR---ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTE 1514
D+T+NS V W P+ + I GY + + + R ++ + + L G
Sbjct: 8415 EDVTSNSMLVKWNEPKDNGSPILGYWLEKREVNSTHWSRVNKSLLNALKANVDGLLEGLT 8474
Query: 1515 YVVSIVALN----GREESPLLIGQQSTVSD--------VPRDLEVVAATPTSLLISWDAP 1562
YV + A N G+ P T D +PR V + T++ + W+ P
Sbjct: 8475 YVFRVCAENAAGPGKFSPP---SDPKTAHDPISPPGPPIPR---VTDTSSTTIELEWEPP 8528
Query: 1563 AVT----VRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDS 1618
A + Y + G N + T+ ++ G DY + V AV G+
Sbjct: 8529 AFNGGGEIVGYFVDKQLVGTNEWSRCTEKMIKVRQYTVKEIREGADYKLRVSAVNAAGEG 8588
Query: 1619 -PASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTK 1677
P ++P+++ E +P +++ +SVK R+ P PTK
Sbjct: 8589 PPGETQPVTV---AEPQEPPAVEL------DVSVKGGIQIMAGKTLRIPAVVTGRPVPTK 8639
Query: 1678 --TKTAGP-DQTEMTIEGLQPTVEYVVS-----------VYAQNPSGESQPLVQTAVTNI 1723
TK G D+ + I+ + E ++ + A N G + V ++
Sbjct: 8640 VWTKEEGELDKDRVVIDNVGTKSELIIKDALRKDHGRYVITATNSCGSKFAAARVEVFDV 8699
Query: 1724 DRP-KGLAFTDVDVDSIKIAWESPQ----GQVSRYRVTYSSPEDGIHELFPAPDGEEDTA 1778
P L + + W P+ +++ + + + +H + E
Sbjct: 8700 PGPVLDLKPVVTNRKMCLLNWSDPEDDGGSEITGFIIERKDAK--MHTWRQPIETERSKC 8757
Query: 1779 ELQGLRPGSEYTVSVVALH-----DDMESQPLIGTQSTAIP-APTDLKFTQVTPTSLSAQ 1832
++ GL G EY V+A + +E P++ P +P L +T+ T ++++
Sbjct: 8758 DITGLLEGQEYKFRVIAKNKFGCGPPVEIGPILAVDPLGPPTSPERLTYTERTKSTITLD 8817
Query: 1833 WTPPNVQ----LTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKD 1888
W P + GY + +K + ++S +V L YE V A+ +
Sbjct: 8818 WKEPRSNGGSPIQGYIIEKRRHDKPDFERVNKRLCPTTSFLVENLDEHQMYEFRVKAVNE 8877
Query: 1889 TLTSRPA--QGVVTTLENVSPPRRARVTDATETTIT-------------------ISWRT 1927
S P+ VV + V P + R++ +T I W +
Sbjct: 8878 IGESEPSLPLNVVIQDDEVPPTIKLRLSVRGDTIKVKAGEPVHIPADVTGLPMPKIEW-S 8936
Query: 1928 KTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVV 1987
K ET+ DA+ + + K ++ GT YT+ + R V
Sbjct: 8937 KNETVIEKPTDALQITKEEVSRSEAKTELSIPKAVREDKGT------YTVTASNRLGSVF 8990
Query: 1988 IDASTAI-DAPSNLRFLATT---PNSLLVSWQPP----RARITGYII 2026
+ + D PS R LA T S ++W P + IT Y+I
Sbjct: 8991 RNVHVEVYDRPSPPRNLAVTDIKAESCYLTWDAPLDNGGSEITHYVI 9037
Score = 94.0 bits (232), Expect = 2e-18
Identities = 154/662 (23%), Positives = 253/662 (38%), Gaps = 93/662 (14%)
Query: 1538 VSDVP---RDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTA 1594
V DVP R+LEV + ++W+ P I Y + + + + ++ +
Sbjct: 6589 VIDVPGPVRNLEVTETFDGEVSLAWEEPLTDGGSKIIGYVVERRDIKRKTWVLATDRAES 6648
Query: 1595 ---TISGL-KPGVDYTITVYAVT--GRGDSPASSKPISINYRTEIDKPS-QMQVTDVQDN 1647
T++GL K GV+Y V A G G+ + P+ + ++ P + +TDV
Sbjct: 6649 CEFTVTGLQKGGVEYLFRVSARNRVGTGEPVETDNPVEARSKYDVPGPPLNVTITDVNRF 6708
Query: 1648 SISVKWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSV 1703
+S+ W P + +T Y + K T + T+ + EY V
Sbjct: 6709 GVSLTWEPPEYDGGAEITNYVIELRDKTSIRWDTAMTVRAEDLSATVTDVVEGQEYSFRV 6768
Query: 1704 YAQNPSGESQPLVQTAVTN----IDRPK---GLAFTDVDVDSIKIAWESPQGQVSRYRVT 1756
AQN G +P T I+RP L +D S+++ WE P +
Sbjct: 6769 RAQNRIGVGKPSAATPFVKVADPIERPSPPVNLTSSDQTQSSVQLKWEPPLKDGGSPILG 6828
Query: 1757 Y--SSPEDGIH-------ELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIG 1807
Y E+G +L P E T ++ GL G++Y V A + S P
Sbjct: 6829 YIIERCEEGKDNWIRCNMKLVP-----ELTYKVTGLEKGNKYLYRVSAENKAGVSDP--- 6880
Query: 1808 TQSTAIPAPTDLKFTQVTPT-SLSA-----QWTPPN-----VQLTGY-RVRVT-----PK 1850
+ I P V PT LSA + PN V TGY R T
Sbjct: 6881 ---SEILGPLTADDAFVEPTMDLSAFKDGLEVIVPNPITILVPSTGYPRPTATWCFGDKV 6937
Query: 1851 EKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGV--VTTLENVSPP 1908
+TG ++ + +V+S + + + +Y LK + G V + S P
Sbjct: 6938 LETGDRVKMKTLSAYAELVISP---SERSDKGIYTLKLENRVKTISGEIDVNVIARPSAP 6994
Query: 1909 RRARVTDATETTITISWRTKTET----ITGFQVDAVPANGQTPIQRTIKPDVRSYTITGL 1964
+ + D T+ ++ ++W + +TG+ V+ + +T + +T+ L
Sbjct: 6995 KELKFGDITKDSVHLTWEPPDDDGGSPLTGYVVEKREVSRKTWTKVMDFVTDLEFTVPDL 7054
Query: 1965 QPGTDYKIYLYTLNDNARSSPVVIDA-------STAIDAPSNLRFLATTPNSLLVSWQPP 2017
G +Y + N P +D +T D P N+++ T NS+ ++W PP
Sbjct: 7055 VQGKEYLFKVCARNKCGPGEPAYVDEPVNMSTPATVPDPPENVKWRDRTANSIFLTWDPP 7114
Query: 2018 R----ARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKS 2073
+ +RI GYI++ GS P T+ +TGLE G Y V AL S
Sbjct: 7115 KNDGGSRIKGYIVERCPRGSDKWVACGEP-VAETKMEVTGLEEGKWYAYRVKALNRQGAS 7173
Query: 2074 EPLIGRKKTDELPQLVTLPHPNLHGPEILDVPSTVQKTPFVTHPGYDTGNGIQLPGTSGQ 2133
+P + T+E+ + T P + LDV T G I+LP T
Sbjct: 7174 KP---SRPTEEIQAVDTQEAPEI----FLDVKLLAGLT-------VKAGTKIELPATVTG 7219
Query: 2134 QP 2135
+P
Sbjct: 7220 KP 7221
Score = 90.5 bits (223), Expect = 2e-17
Identities = 354/1666 (21%), Positives = 582/1666 (34%), Gaps = 229/1666 (13%)
Query: 624 NSHPIQWNAPQ---PSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKG--LKPGVVYE 678
+S + W P+ S I+ YI+ R S W+ + + TIK LK G Y+
Sbjct: 15759 DSITLSWGPPKYDGGSSINNYIVEKRD-TSTTTWQ--IVSATVARTTIKACRLKTGCEYQ 15815
Query: 679 GQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVV 738
++ + +YG + T V P +P+V S + S V
Sbjct: 15816 FRIAAENRYGKSTYLNSEPTVAQYPFKVPG-------PPGTPVVTLS------SRDSMEV 15862
Query: 739 SWVSASDTVSGFRVEYELS-EEGDEPQYLDL---PSTATSVNIPDLLPGRKYI--VNVYQ 792
W + Y L +E + ++ L P T L G +Y V+
Sbjct: 15863 QWNEPISDGGSRVIGYHLERKERNSILWVKLNKTPIPQTKFKTTGLEEGVEYEFRVSAEN 15922
Query: 793 ISEDGEQSLILSTSQTTAPDAPPD-PTVDQVDDTSIVVRWSRPQ----APITGYRIVYSP 847
I G+ S + P PP P V S+ ++W +P + ITGY +
Sbjct: 15923 IVGIGKPSKVSECYVARDPCDPPGRPEAIIVTRNSVTLQWKKPTYDGGSKITGYIVEKKE 15982
Query: 848 SVEG---SSTELNLPETANSVTLSDLQPGVQYNITIYA------VEENQESTPVVIQQET 898
EG ++ N+ +T VT L +Y + A E EST + ++
Sbjct: 15983 LPEGRWMKASFTNIIDTHFEVT--GLVEDHRYEFRVIARNAAGVFSEPSESTGAITARDE 16040
Query: 899 TGTPRSDTVPSPRDLQFVEVTD---VKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLP 955
PR P +D V + V I P + + I + + RL
Sbjct: 16041 VDPPRISMDPKYKDTIVVHAGESFKVDADIYGKPIPT------IQWIKGDQELSNTARLE 16094
Query: 956 ISRNTFAEVTGLSPGV-----TYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNE-T 1009
I FA + V Y K V+ G S + + + P ++ T
Sbjct: 16095 IKSTDFATSLSVKDAVRVDSGNYILKAKNVA-GERSVTVNVKVLDRPGPPEGPVVISGVT 16153
Query: 1010 DSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVS 1065
+ W PP + I Y + T R + + L +EYT
Sbjct: 16154 AEKCTLAWKPPLQDGGSDIINYIVERRETSRLVWTVVDANVQTLSCKVTKLLEGNEYTFR 16213
Query: 1066 LVAIKGNQ-----ESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWT-PAPR-----IG 1114
++A+ ES + P + P T VT+ ++++ W PA +G
Sbjct: 16214 IMAVNKYGVGEPLESEPVVAKNPFVVPDAPKAPEVTTVTKDSMIVVWERPASDGGSEILG 16273
Query: 1115 FKLGVRPSQGGEAPREVTSDSGSIV--VSGLTPGVEYVYTIQVLRD-GQERDAP--IVNK 1169
+ L R +G R G + V+GL +Y + + G +P K
Sbjct: 16274 YVLEKRDKEGIRWTRCHKRLIGELRLRVTGLIENHDYEFRVSAENAAGLSEPSPPSAYQK 16333
Query: 1170 VVTPL---SPPTNLHLEANPDTGVLTVSWERSTTP---DITGYRITTTPTNGQQGNSLEE 1223
P+ PP N + + V +SW + +I GY + + +
Sbjct: 16334 ACDPIYKPGPPNNPKVIDITRSSVF-LSWSKPIYDGGCEIQGYIVEKCDVSVGEWTMCTP 16392
Query: 1224 VVHADQSSCTFDNLSPGLEYNVSVYTVKD----DKESVPISDTIIPEVPQLTDLSFVDIT 1279
++++ + L EYN + + + VP I+ E + D+
Sbjct: 16393 PTGINKTNIEVEKLLEKHEYNFRICAINKAGVGEHADVP-GPIIVEEKLEAPDI------ 16445
Query: 1280 DSSIGLRWTPLNSSTIIGYRITVVAAGEGIP----------IFEDFVDSSVGYYTVTGLE 1329
D + LR +N R+ V G P I + + +T L+
Sbjct: 16446 DLDLELRKI-INIRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTSSFTSLVLD 16504
Query: 1330 PGIDYDISVITLI----NGGESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAPPPSID 1385
YD TL +G +SA T+ PP +L+ T I D++ +TW PP +D
Sbjct: 16505 NVNRYDSGKYTLTLENSSGTKSAFVTVRVLDTPSPPVNLKVTEITKDSVSITW-EPPLLD 16563
Query: 1386 LTNFLVRYSPVKNE---EDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLR 1442
+ + Y K E + A + + N+ + L G Y V++ E P +
Sbjct: 16564 GGSKIKNYIVEKREATRKSYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAENEYGIGLPAQ 16623
Query: 1443 GRQKTGL----DSPTGIDFSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPRE 1494
+ P I D+T NS ++ W P + I Y + +H
Sbjct: 16624 TADPIKVAEVPQPPGKITVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKHSEKWSEC 16683
Query: 1495 DRVPHSRNSITLTNLTPGTEYVVSIVALNGREES-PLLIGQQSTVSDVPRDLEVVAA-TP 1552
RV + +TNLT G EY+ +VA+N + S P + D+ + +V A +
Sbjct: 16684 ARVKSLQ--AVITNLTQGEEYLFRVVAVNEKGRSDPRSLAVPIVAKDLVIEPDVKPAFSS 16741
Query: 1553 TSLLISWD----APAVTVRYYRITYGETGGNSPVQEFT---VPGSKSTATIS----GLKP 1601
S+ + D P IT+ + G P+++ T V S T+S
Sbjct: 16742 YSVQVGQDLKIEVPISGRPKPTITWTKDG--LPLKQTTRINVTDSLDLTTLSIKETHKDD 16799
Query: 1602 GVDYTITVYAVTGRGDSPASSKPISINYRTEIDKP----SQMQVTDVQDNSISVKWLP-- 1655
G Y ITV V G+ K SI T +DKP ++ DV SI++ W P
Sbjct: 16800 GGQYGITVANVVGQ-------KTASIEIVT-LDKPDPPKGPVKFDDVSAESITLSWNPPL 16851
Query: 1656 --SSSPVTGYRV-----TTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNP 1708
+T Y V TTT + T +T + + L+ EY ++A+N
Sbjct: 16852 YTGGCQITNYIVQKRDTTTTVWDVVSATVARTT------LKVTKLKTGTEYQFRIFAENR 16905
Query: 1709 SG-----ESQPLVQTAVTNIDRPKGLAF-TDVDVDSIKIAWESPQGQVSRYRVTYSSPED 1762
G ES P+V P G F T + DS+ I W P + Y
Sbjct: 16906 YGQSFALESDPIVAQYPYKEPGPPGTPFATAISKDSMVIQWHEPVNNGGSPVIGYHLERK 16965
Query: 1763 GIHELFPAPDGE---EDTA-ELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTD 1818
+ + + DT + Q L G EY V A + + ++ P D
Sbjct: 16966 ERNSILWTKVNKTIIHDTQFKAQNLEEGIEYEFRVYAENIVGVGKASKNSECYVARDPCD 17025
Query: 1819 LKFT----QVTPTSLSAQWTPP----NVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVV 1870
T V ++ QWT P +TGY V MK + V
Sbjct: 17026 PPGTPEPIMVKRNEITLQWTKPVYDGGSMITGYIVEKRDLPDGRWMKASFTNVIETQFTV 17085
Query: 1871 SGLMVATKYEVSVYALKDT-LTSRPAQ--GVVTTLENVSPPRRARVTDATETTITISWRT 1927
SGL +YE V A S+P+ G +T + V PR + +T + + T
Sbjct: 17086 SGLTEDQRYEFRVIAKNAAGAISKPSDSTGPITAKDEVELPRISMDPKFRDTIVVNAGET 17145
Query: 1928 KTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQ-PGTDYKIYL------------ 1974
F+++A P ++ D + TD+K L
Sbjct: 17146 -------FRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRIDGGQ 17198
Query: 1975 YTLNDN----ARSSPV---VIDASTAIDAPSNLRFLATTPNSLLVSWQPP----RARITG 2023
Y L + ++S PV V+D + P ++ T ++W PP + I+
Sbjct: 17199 YILRASNVAGSKSFPVNVKVLDRPGPPEGP--VQVTGVTSEKCSLTWSPPLQDGGSDISH 17256
Query: 2024 YIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTD 2083
Y+++ ++ S V +T L G EY ++A+ EPL +
Sbjct: 17257 YVVE-KRETSRLAWTVVASEVVTNSLKVTKLLEGNEYVFRIMAVNKYGVGEPL------E 17309
Query: 2084 ELPQLVTLPHPNLHGPEILDVPSTVQKTPFVTHPGYDTGNGIQLPG 2129
P L+ P P+ L+V + + + V D+ G ++ G
Sbjct: 17310 SAPVLMKNPFVLPGPPKSLEVTNIAKDSMTVCWNRPDSDGGSEIIG 17355
Score = 86.7 bits (213), Expect = 3e-16
Identities = 349/1678 (20%), Positives = 599/1678 (35%), Gaps = 279/1678 (16%)
Query: 628 IQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISI 684
+ W+ P+ S I+ +I+ R + W++ I + I GL G Y+ ++I+
Sbjct: 8718 LNWSDPEDDGGSEITGFIIE-RKDAKMHTWRQP-IETERSKCDITGLLEGQEYKFRVIAK 8775
Query: 685 QQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWV--- 741
++G PV + P + TE T S+ + W
Sbjct: 8776 NKFG-------------CGPPVEIGPILAVDPLGPPTSPERLTYTERTKSTITLDWKEPR 8822
Query: 742 -SASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQS 800
+ + G+ +E ++ D + TS + +L + Y V ++E GE
Sbjct: 8823 SNGGSPIQGYIIEKRRHDKPDFERVNKRLCPTTSFLVENLDEHQMYEFRVKAVNEIGESE 8882
Query: 801 LILSTSQTTAPDAPPDPTVD---QVDDTSIVVRWSRP---QAPITGYRIVYSPSVEGSST 854
L + D P PT+ V +I V+ P A +TG + P +E S
Sbjct: 8883 PSLPLNVVIQDDEVP-PTIKLRLSVRGDTIKVKAGEPVHIPADVTGLPM---PKIEWSKN 8938
Query: 855 E--LNLPETANSVTLSDLQPG-VQYNITI-YAVEENQESTPVVIQQETTGTPRS------ 904
E + P A +T ++ + ++I AV E++ + V R+
Sbjct: 8939 ETVIEKPTDALQITKEEVSRSEAKTELSIPKAVREDKGTYTVTASNRLGSVFRNVHVEVY 8998
Query: 905 DTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPGEHGQRLPISRNT 960
D PR+L ++ + W P S +T Y +D + + + NT
Sbjct: 8999 DRPSPPRNLAVTDIKAESCYLTWDAPLDNGGSEITHYVIDKRDASRKKAEWEEVT---NT 9055
Query: 961 FAE----VTGLSPGVTYYFKV-----FAVSHGRESKPLTAQQTTKLDAPTNL-QFVNETD 1010
E + L P Y F+V + +S +S + Q +L P + + T
Sbjct: 9056 AVEKRYGIWKLIPNGQYEFRVRAVNKYGISDECKSDKVVIQDPYRLPGPPGKPKVLARTK 9115
Query: 1011 STVLVRWTPPR----AQITGYRLTVGLTRRGQPRQY----------NVGPSVSKYPLRNL 1056
++LV WTPP + ITGY L +R + Y VG ++ + L
Sbjct: 9116 GSMLVSWTPPLDNGGSPITGY----WLEKREEGSPYWSRVSRAPITKVGLKGVEFNVPRL 9171
Query: 1057 QPASEYTVSLVAIKG-------NQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTP 1109
+Y +AI P+ G PG P + T+++I + W P
Sbjct: 9172 LEGVKYQFRAMAINAAGIGPPSEPSDPEVAGD-PIFPPGPPSCPEVKDKTKSSISLGWKP 9230
Query: 1110 APRIGFKLGVRPSQGG--EAPREVTSDSGSI------------VVSGLTPGVEYVYTIQV 1155
K G P +G E E T+D + VV L +Y + ++
Sbjct: 9231 PA----KDGGSPIKGYIVEMQEEGTTDWKRVNEPDKLITTCECVVPNLKELRKYRFRVKA 9286
Query: 1156 LRD-GQERDAPIVNKV-VTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPT 1213
+ + G+ + ++ T + + ++ ++ + + P + R T +
Sbjct: 9287 VNEAGESEPSDTTGEIPATDIQEEPEVFIDIGAQDCLVCKAGSQIRIPAVIKGRPTPKSS 9346
Query: 1214 ---NGQQGNSLEEVVH---ADQSSCTFDNLSPGL----------EYNVSVYTVKDDKES- 1256
+G+ ++++ VH D T +N S + +Y+++ K +
Sbjct: 9347 WEFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECKRSHTGKYSITAKNKAGQKTAN 9406
Query: 1257 --VPISDTIIPEVPQLTDLSFVDITDSSIGLRWTPLNSS---TIIGYRITVVAAGEGIPI 1311
V + D +P P+ DL DIT S L W + I GY I +G
Sbjct: 9407 CRVKVMD--VPGPPK--DLKVSDITRGSCRLSWKMPDDDGGDRIKGYVIEKRTI-DGKAW 9461
Query: 1312 FEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAV-------PPPTDL 1364
+ D + V L Y V G P Q+T PP L
Sbjct: 9462 TKVNPDCGSTTFVVPDLLSEQQYFFRVRAENRFGIGPPVETIQRTTARDPIYPPDPPIKL 9521
Query: 1365 RFTNIGPDTMRVTWAPPPS---IDLTNFLVR---YSPVK---------NEEDVAELSISP 1409
+ I +T+ ++W PP + +T+++V + P N+ DV EL +
Sbjct: 9522 KIGLITKNTVHLSWKPPKNDGGSPVTHYIVECLAWDPTGTKKEAWRQCNKRDVEELQFTV 9581
Query: 1410 SDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGL---DSPTGIDFSDI--TANS 1464
D L+ G EY V +V S P D P ID +
Sbjct: 9582 ED-------LVEGGEYEFRVKAVNAAGVSKPSATVGPCDCQRPDMPPSIDLKEFMEVEEG 9634
Query: 1465 FTVHWIA-----PRATITGYRIRH----------HPEHFSGRPREDR----VPHSRNSIT 1505
V+ +A P T+T ++ + H + +D +P SR S T
Sbjct: 9635 TNVNIVAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDT 9694
Query: 1506 LTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAP--- 1562
Y ++ V G + + ++ + + + +SW P
Sbjct: 9695 GL-------YTITAVNNLGTASKEMRLNVLGRPGPPVGPIKFESVSADQMTLSWFPPKDD 9747
Query: 1563 -AVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRG-DSPA 1620
+ Y I E + V + P + T TI L G +Y + A G P
Sbjct: 9748 GGSKITNYVIEKREANRKTWVHVSSEP-KECTYTIPKLLEGHEYVFRIMAQNKYGIGEPL 9806
Query: 1621 SSKPISI-NYRTEIDKPSQMQVTDVQDNSISVKW----LPSSSPVTGYRVT---TTPKN- 1671
S+P + N + P + V+ V NS++V W SPVTGY + TT K
Sbjct: 9807 DSEPETARNLFSVPGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPVTGYWLEMKDTTSKRW 9866
Query: 1672 ---GPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSG---ESQPLVQTAVTNIDR 1725
P K T G + GL +Y VYA N +G S P +
Sbjct: 9867 KRVNRDPIKAMTLG---VSYKVTGLIEGSDYQFRVYAINAAGVGPASLPSDPATARDPIA 9923
Query: 1726 PKGLAF---TDVDVDSIKIAWESPQ----GQVSRYRVTYSSPEDGIHELFPAPDGEEDTA 1778
P G F TD S + W P +V+ Y V Y E+G E D E
Sbjct: 9924 PPGPPFPKVTDWTKSSADLEWSPPLKDGGSKVTGYIVEYK--EEGKEEWEKGKDKEVRGT 9981
Query: 1779 EL--QGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPT-SLSAQWTP 1835
+L GL+ G+ Y V A++ +P G + I ++K V+P L A
Sbjct: 9982 KLVVTGLKEGAFYKFRVRAVNIAGIGEP--GEVTDVI----EMKDRLVSPDLQLDASVRD 10035
Query: 1836 PNVQLTGYRVRVT-------PKEKTGPMKEINLAPDSS--SVVVSGLMVATKYEVS---V 1883
V G +R+ P T M E L +++ + +S MV + S V
Sbjct: 10036 RIVVHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEATIETTAISSSMVIKNCQRSHQGV 10095
Query: 1884 YAL--KDTLTSRPAQGVVTTLENVSPPRRARVT-DATETTITISWRTKTET----ITGFQ 1936
Y+L K+ R +V L+ P + + T + ++W + + IT +
Sbjct: 10096 YSLLAKNEAGERKKTIIVDVLDVPGPVGTPFLAHNLTNESCKLTWFSPEDDGGSPITNYV 10155
Query: 1937 VDAVPANGQ--TPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLND-------NARSSPVV 1987
++ ++ + TP+ T+ ++ T+ GL G Y + N + V+
Sbjct: 10156 IEKRESDRRAWTPVTYTVTR--QNATVQGLIQGKAYFFRIAAENSIGMGPFVETSEALVI 10213
Query: 1988 IDASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREVVPRPR 2043
+ T + P +L T N++ ++W PP+ + I Y+++ G+ V
Sbjct: 10214 REPITVPERPEDLEVKEVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEKFHKVTNDN 10273
Query: 2044 PGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELPQLVT----LPHPNLH 2097
+ T+ GL+ G Y V A+ ++G+ K + +T L P LH
Sbjct: 10274 LLSRKYTVKGLKEGDTYEYRVSAVN-------IVGQGKPSFCTKPITCKDELAPPTLH 10324
Score = 86.7 bits (213), Expect = 3e-16
Identities = 320/1612 (19%), Positives = 550/1612 (34%), Gaps = 233/1612 (14%)
Query: 630 WNAPQPSH---ISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQ 686
W+ P+ IS Y++ R +S W E +Y L G+ Y+ ++ + +
Sbjct: 14683 WDPPENDGGVPISNYVVEMRQTDST-TWVELATTVIRTTYKATRLTTGLEYQFRVKAQNR 14741
Query: 687 YGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSW----VS 742
YG +TS + P + VT +T S +SW
Sbjct: 14742 YG-------------VGPGITSACIVANYPFKVPGPPGTPQVTAVTKDSMTISWHEPLSD 14788
Query: 743 ASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNI---PDLLPGRKYIVNVYQISEDGEQ 799
+ G+ VE +E + + + NI L G Y V + G+
Sbjct: 14789 GGSPILGYHVE---RKERNGILWQTVSKALVPGNIFKSSGLTDGIAYEFRVIAENMAGKS 14845
Query: 800 SLILSTSQTTAPDA---PPDPTVDQVDDTSIVVRWSRPQAP----ITGYRIVYSPSVEGS 852
+ A D P P + ++ ++W++P+ IT Y + G
Sbjct: 14846 KPSKPSEPMLALDPIDPPGKPVPLNITRHTVTLKWAKPEYTGGFKITSYIVEKRDLPNGR 14905
Query: 853 STELNLPETA-NSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPR 911
+ N N T+S L Y + A +P + + D V +P+
Sbjct: 14906 WLKANFSNILENEFTVSGLTEDAAYEFRVIAKNAAGAISPP--SEPSDAITCRDDVEAPK 14963
Query: 912 ---DLQFVEVTDVKV----------------TIMWTPPESAVTG-----YRVDVIPVNLP 947
D++F + +K T+ W+ + G ++ NL
Sbjct: 14964 IKVDVKFKDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLV 15023
Query: 948 GEHGQRLPISRNTFAEVTGLSPG--VTYYFKVFAVSH-GRESKPLTAQQTTKLDAPTNLQ 1004
+ R T +T +PG + F V + G PL + T
Sbjct: 15024 NKDSTRRDSGAYT---LTATNPGGFAKHIFNVKVLDRPGPPEGPLAVTEVTS-------- 15072
Query: 1005 FVNETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPAS 1060
++ W PP A+I Y + T R V+K + L +
Sbjct: 15073 ------EKCVLSWFPPLDDGGAKIDHYIVQKRETSRLAWTNVASEVQVTKLKVTKLLKGN 15126
Query: 1061 EYTVSLVAIK--GNQESPKATGVFTTLQPGSSIPPYNTEVTETT---IVITWTPAPRIGF 1115
EY ++A+ G E ++ V G PP N EVT T +V+ W G
Sbjct: 15127 EYIFRVMAVNKYGVGEPLESEPVLAVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGG 15186
Query: 1116 K-----LGVRPSQGGEAPREVTSDSGSIV-----VSGLTPGVEYVYTIQVLR----DGQE 1161
+ R + G+ R + + ++ VSGLT G EY + I
Sbjct: 15187 SEIINYIVERRDKAGQ--RWIKCNKKTLTDLRYKVSGLTEGHEYEFRIMAENAAGISAPS 15244
Query: 1162 RDAPIVNKVVTPLSP-PTNLHLEANPDTGVLTVSWERSTTP---DITGYRITTTPTNGQQ 1217
+P T P P + ++++W + +ITGY + +
Sbjct: 15245 PTSPFYKACDTVFKPGPPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIALPEEDE 15304
Query: 1218 GNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPEVPQLTDLSFVD 1277
+ +S T L+ EY + +Y + + P ++P P+ D
Sbjct: 15305 WQIVTPPAGLKATSYTITGLTENQEYKIRIYAMNSEGLGEP---ALVPGTPKAEDRMLPP 15361
Query: 1278 ITDSSIGLRWTPLNSSTIIGYRITVVAAGEGIP-----------IFEDFVDSSVGY-YTV 1325
+ LR + R+ V G P + + ++S+ Y +
Sbjct: 15362 EIELDADLRKV-VTIRACCTLRLFVPIKGRPAPEVKWARDHGESLDKASIESTSSYTLLI 15420
Query: 1326 TGLEPGIDYDISVITLIN--GGESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAPPPS 1383
G D ++T+ N G +SA + PP DL+ + ++ +TW PP
Sbjct: 15421 VGNVNRFDSGKYILTVENSSGSKSAFVNVRVLDTPGPPQDLKVKEVTKTSVTLTW-DPPL 15479
Query: 1384 IDLTNFLVRYSPVKNEEDVAELSISPSD---NAVVLTNLLPGTEYVVSVSSVYEQHESTP 1440
+D + + Y K E S ++ + + L G Y V + E P
Sbjct: 15480 LDGGSKIKNYIVEKRESTRKAYSTVATNCHKTSWKVDQLQEGCSYYFRVLAENEYGIGLP 15539
Query: 1441 LRGRQKTGLDS----PTGIDFSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRP 1492
+ P I D+T NS ++ W P + I GY + +
Sbjct: 15540 AETAESVKASERPLPPGKITLMDVTRNSVSLSWEKPEHDGGSRILGYIVEMQTKGSDKWA 15599
Query: 1493 REDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAA-- 1550
V + T+T L G EY + A N E + +Q +V + +DL + A
Sbjct: 15600 TCATVKVTE--ATITGLIQGEEYSFRVSAQN---EKGISDPRQLSVPVIAKDLVIPPAFK 15654
Query: 1551 ----TPTSLL---ISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGL--KP 1601
T T L + D P + +T+ + N P+++ T ++ST S L K
Sbjct: 15655 LLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKD--NVPLKQTTRVNAESTENNSLLTIKD 15712
Query: 1602 GVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQ----MQVTDVQDNSISVKWLP-- 1655
+ Y V + + + +++ +DKP +++ +V +SI++ W P
Sbjct: 15713 ACREDVGHYVVKLTNSAGEAIETLNV---IVLDKPGPPTGPVKMDEVTADSITLSWGPPK 15769
Query: 1656 --SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEG--LQPTVEYVVSVYAQNPSGE 1711
S + Y V K T + TI+ L+ EY + A+N G+
Sbjct: 15770 YDGGSSINNYIVE---KRDTSTTTWQIVSATVARTTIKACRLKTGCEYQFRIAAENRYGK 15826
Query: 1712 S-----QPLVQTAVTNIDRPKGLAFTDVDV-DSIKIAWESPQGQVSRYRVTYSSPEDGIH 1765
S +P V + P G + DS+++ W P + Y +
Sbjct: 15827 STYLNSEPTVAQYPFKVPGPPGTPVVTLSSRDSMEVQWNEPISDGGSRVIGYHLERKERN 15886
Query: 1766 ELF-------PAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTD 1818
+ P P + T GL G EY V A + +P ++ P D
Sbjct: 15887 SILWVKLNKTPIPQTKFKTT---GLEEGVEYEFRVSAENIVGIGKPSKVSECYVARDPCD 15943
Query: 1819 L----KFTQVTPTSLSAQWTPPNV----QLTGYRVRVTPKEKTGPMKEINLAPDSSSVVV 1870
+ VT S++ QW P ++TGY V + MK + V
Sbjct: 15944 PPGRPEAIIVTRNSVTLQWKKPTYDGGSKITGYIVEKKELPEGRWMKASFTNIIDTHFEV 16003
Query: 1871 SGLMVATKYEVSVYALKDT-LTSRPAQ--GVVTTLENVSPPRRARVTDATETTITISWRT 1927
+GL+ +YE V A + S P++ G +T + V PPR + +T + + +
Sbjct: 16004 TGLVEDHRYEFRVIARNAAGVFSEPSESTGAITARDEVDPPRISMDPKYKDTIVVHAGES 16063
Query: 1928 KTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQ-PGTDYKIYLYTLNDNAR--SS 1984
F+VDA P + IK D L+ TD+ L ++ D R S
Sbjct: 16064 -------FKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSL-SVKDAVRVDSG 16115
Query: 1985 PVVIDASTAIDAPS---NLRFL-------------ATTPNSLLVSWQPPR----ARITGY 2024
++ A S N++ L T ++W+PP + I Y
Sbjct: 16116 NYILKAKNVAGERSVTVNVKVLDRPGPPEGPVVISGVTAEKCTLAWKPPLQDGGSDIINY 16175
Query: 2025 IIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPL 2076
I++ + VV +T L G EYT ++A+ EPL
Sbjct: 16176 IVERRETSRLVWTVVDA-NVQTLSCKVTKLLEGNEYTFRIMAVNKYGVGEPL 16226
Score = 86.3 bits (212), Expect = 3e-16
Identities = 362/1829 (19%), Positives = 635/1829 (34%), Gaps = 273/1829 (14%)
Query: 628 IQWNAPQPS---HISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISI 684
+ WN P + I+ YI++ R + W + + + LK G Y+ ++ +
Sbjct: 16845 LSWNPPLYTGGCQITNYIVQKRDTTTTV-WDVVSATVARTTLKVTKLKTGTEYQFRIFAE 16903
Query: 685 QQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSAS 744
+YG D P+ + E P AT+ I+ S V+ W
Sbjct: 16904 NRYGQSFALESD--------PIVAQYPYKEPGPPGTPFATA-----ISKDSMVIQWHEPV 16950
Query: 745 DTVSGFRVEYELS-EEGDEPQYLDLPSTA---TSVNIPDLLPG-----RKYIVNVYQISE 795
+ + Y L +E + + + T T +L G R Y N+ + +
Sbjct: 16951 NNGGSPVIGYHLERKERNSILWTKVNKTIIHDTQFKAQNLEEGIEYEFRVYAENIVGVGK 17010
Query: 796 DGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ----APITGYRIVYSPSVEG 851
+ S P P+P + V I ++W++P + ITGY + +G
Sbjct: 17011 ASKNSECYVARDPCDPPGTPEPIM--VKRNEITLQWTKPVYDGGSMITGYIVEKRDLPDG 17068
Query: 852 ---SSTELNLPETANSVTLSDLQPGVQYNITIYA------VEENQESTPVVIQQETTGTP 902
++ N+ ET T+S L +Y + A + + +ST + ++ P
Sbjct: 17069 RWMKASFTNVIET--QFTVSGLTEDQRYEFRVIAKNAAGAISKPSDSTGPITAKDEVELP 17126
Query: 903 RSDTVPSPRDLQFVEVTDV-----------KVTIMWTPPESAVTGYRVDVIPVNLPGEHG 951
R P RD V + TI W + + E
Sbjct: 17127 RISMDPKFRDTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEI--------------EES 17172
Query: 952 QRLPISRNTFAEVTGLSPGVT-----YYFKVFAVSHGRESKPLTAQQTTKLDAPTN-LQF 1005
R I F + + + Y + V+ G +S P+ + + P +Q
Sbjct: 17173 ARCEIKNTDFKALLIVKDAIRIDGGQYILRASNVA-GSKSFPVNVKVLDRPGPPEGPVQV 17231
Query: 1006 VNETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASE 1061
T + W+PP + I+ Y + T R + + L +E
Sbjct: 17232 TGVTSEKCSLTWSPPLQDGGSDISHYVVEKRETSRLAWTVVASEVVTNSLKVTKLLEGNE 17291
Query: 1062 YTVSLVAIK--GNQESPKATGVFTT---LQPGSSIPPYNTEVT---ETTIVITWTPAPR- 1112
Y ++A+ G E ++ V + PG PP + EVT + ++ + W
Sbjct: 17292 YVFRIMAVNKYGVGEPLESAPVLMKNPFVLPG---PPKSLEVTNIAKDSMTVCWNRPDSD 17348
Query: 1113 -----IGFKLGVRPSQGGE----APREVTSDSGSIVVSGLTPGVEYVYTIQVLRD---GQ 1160
IG+ + R G R +T + V+GLT EY + + G+
Sbjct: 17349 GGSEIIGYIVEKRDRSGIRWIKCNKRRITDLR--LRVTGLTEDHEYEFRVSAENAAGVGE 17406
Query: 1161 ERDAPIVNKVVTPL---SPPTNLHLEANPDTGVLTVSWERSTTP---DITGYRITTTPTN 1214
A + K P+ PPTN H+ + +T++W + +I GY + +
Sbjct: 17407 PSPATVYYKACDPVFKPGPPTNAHI-VDTTKNSITLAWGKPIYDGGSEILGYVVEICKAD 17465
Query: 1215 GQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDK--ESVPISDTIIPE----VP 1268
++ + + L+ EY + V + E+ + T+ PE P
Sbjct: 17466 EEEWQIVTPQTGLRVTRFEISKLTEHQEYKIRVCALNKVGLGEATSVPGTVKPEDKLEAP 17525
Query: 1269 QLTDLSFVDITDSSIGLRWTPLNSSTII--GYRITVVAAGEGIPIFEDFVDSSVGYYT-V 1325
+L DL + L ++ G + +G P E G +T
Sbjct: 17526 EL-DLD-------------SELRKGIVVRAGGSARIHIPFKGRPTPEITWSREEGEFTDK 17571
Query: 1326 TGLEPGIDYD---------------ISVITLINGGESAPTTLTQQTAVPPPTDLRFTNIG 1370
+E G++Y I + +G +SA T+ PP +L +
Sbjct: 17572 VQIEKGVNYTQLSIDNCDRNDAGKYILKLENSSGSKSAFVTVKVLDTPGPPQNLAVKEVR 17631
Query: 1371 PDTMRVTWAPPPSIDLTNFLVRYSPVKNEED---VAELSISPSDNAVVLTNLLPGTEYVV 1427
D+ + W PP ID + Y K E A +S S + + NL G Y
Sbjct: 17632 KDSAFLVWEPP-IIDGGAKVKNYVIDKRESTRKAYANVSSKCSKTSFKVENLTEGAIYYF 17690
Query: 1428 SVSSVYEQHESTPLR---GRQKTGLDSPTG-IDFSDITANSFTVHWIAPR----ATITGY 1479
V + E P+ + SP G + +D++ S ++ W P + + GY
Sbjct: 17691 RVMAENEFGVGVPVETVDAVKAAEPPSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLGY 17750
Query: 1480 RIRHHPEHFSGRPREDRVPHSRN-SITLTNLTPGTEYVVSIVALNGREES-PLLIGQQST 1537
+ P+ G + V S+ + +T L+ G EY + A N + +S P ++G
Sbjct: 17751 VVEMQPK---GTEKWSIVAESKVCNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVI 17807
Query: 1538 VSDVPRDLEVVAATPTSLL-----ISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKS 1592
D+ + T + + + P + I++ + G P+++ T +
Sbjct: 17808 AKDLTIQPSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDG--EPLKQTTRVNVEE 17865
Query: 1593 TAT--ISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKP-SQMQVTDVQDNSI 1649
TAT + +K G Y VT + +++ +S+ + P ++ +V + +
Sbjct: 17866 TATSTVLHIKEGNKDDFGKYTVTATNSAGTATENLSVIVLEKPGPPVGPVRFDEVSADFV 17925
Query: 1650 SVKWLPSS----SPVTGYRV-----TTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYV 1700
+ W P + ++ Y V TTT + T +T + I L+ EY
Sbjct: 17926 VISWEPPAYTGGCQISNYIVEKRDTTTTTWHMVSATVARTT------IKITKLKTGTEYQ 17979
Query: 1701 VSVYAQNPSGESQPLVQTAVT-----NIDRPKGLAF-TDVDVDSIKIAWESPQGQVSRYR 1754
++A+N G+S PL AV P G F T + D + + W P
Sbjct: 17980 FRIFAENRYGKSAPLDSKAVIVQYPFKEPGPPGTPFVTSISKDQMLVQWHEPVNDGGTKI 18039
Query: 1755 VTYSSPEDGIHELF-------PAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIG 1807
+ Y + + + P D + T GL G EY V A + +P
Sbjct: 18040 IGYHLEQKEKNSILWVKLNKTPIQDTKFKTT---GLDEGLEYEFKVSAENIVGIGKPSKV 18096
Query: 1808 TQSTAIPAPTD----LKFTQVTPTSLSAQWTPP----NVQLTGYRVRVTPKEKTGPMKEI 1859
++ P D + +T +++ +W P ++TGY V MK
Sbjct: 18097 SECFVARDPCDPPGRPEAIVITRNNVTLKWKKPAYDGGSKITGYIVEKKDLPDGRWMKAS 18156
Query: 1860 NLAPDSSSVVVSGLMVATKYEVSVYALKDTLT-SRP--AQGVVTTLENVSPPRRAR---- 1912
+ VSGL+ +YE V A S P + G +T + + P +
Sbjct: 18157 FTNVLETEFTVSGLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARDEIDAPNASLDPKY 18216
Query: 1913 ----VTDATET-TITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQ-P 1966
V A ET + R K + D +T + IK ++ T+
Sbjct: 18217 KDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELE-ETAARMEIKSTIQKTTLVVKDCI 18275
Query: 1967 GTDYKIYLYTLND--NARSSPVVIDASTAIDAPSN-LRFLATTPNSLLVSWQPP----RA 2019
TD Y+ L++ +S P+ + P L+ T ++W PP A
Sbjct: 18276 RTDGGQYILKLSNVGGTKSIPITVKVLDRPGPPEGPLKVTGVTAEKCYLAWNPPLQDGGA 18335
Query: 2020 RITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGR 2079
I+ YII+ + V + +T L PG EY V+A+ EPL
Sbjct: 18336 NISHYIIEKRETSRLSWTQVSTEVQAL-NYKVTKLLPGNEYIFRVMAVNKYGIGEPL--- 18391
Query: 2080 KKTDELPQLVTLPHPNLHGPEILDVPSTVQKTPFVTHPGYDTGNGIQLPGTSGQQPSVGQ 2139
+ P P+ P +V + + + VT G ++ G ++
Sbjct: 18392 ---ESGPVTACNPYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILEKR---- 18444
Query: 2140 QMIFEEHGFRRT-TPPTTATPIRHR------PRPYPPNVGEE--IQIGHIPREDVDYH-- 2188
++ G R T T T +R R Y V E +G V Y
Sbjct: 18445 ----DKEGVRWTKCNKKTLTDLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRAC 18500
Query: 2189 --LYPHGPGLNPNASTGQEALSQTTISWA-PFQD----TSEYIISCHPVGTDEEPLQFRV 2241
LYP GP NP + + S +++W+ P D Y++ DE
Sbjct: 18501 DALYPPGPPSNPKVT--DTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAADEWTTCTPP 18558
Query: 2242 PG-TSTSATLTGLTRGATYNIIVEALKDQ 2269
G T+T L YN + A+ +
Sbjct: 18559 TGLQGKQFTVTKLKENTEYNFRICAINSE 18587
Score = 84.3 bits (207), Expect = 1e-15
Identities = 263/1195 (22%), Positives = 417/1195 (34%), Gaps = 139/1195 (11%)
Query: 624 NSHPIQWNAPQ---PSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQ 680
N+ + WN P+ S I Y+L R + K YT+KGLK G YE +
Sbjct: 10234 NTVTLTWNPPKYDGGSEIINYVLESRLIGTEKFHKVTNDNLLSRKYTVKGLKEGDTYEYR 10293
Query: 681 LISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSW 740
+ ++ G + + + P+T E P + + + +T +F ++
Sbjct: 10294 VSAVNIVGQGK-------PSFCTKPITCK---DELAPPTLHLDFRDKLTIRVGEAFALTG 10343
Query: 741 ---VSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNI-PDLLPGRKYIVNVYQISED 796
VS F+ E ++ E+ D P+T I KY V V +
Sbjct: 10344 RYSGKPKPKVSWFKDEADVLED-DRTHIKTTPATLALEKIKAKRSDSGKYCVVVE--NST 10400
Query: 797 GEQSLILSTSQTTAPDAPPDP-TVDQVDDTSIVVRWSRP----QAPITGYRIVYSPSVEG 851
G + + P P P + D+V +V+ W P + IT Y I +
Sbjct: 10401 GSRKGFCQVNVVDRPGPPVGPVSFDEVTKDYMVISWKPPLDDGGSKITNYIIEKKEVGKD 10460
Query: 852 SSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPR 911
+ + +S L G Y I+A S P+V ++ VP
Sbjct: 10461 VWMPVTSASAKTTCKVSKLLEGKDYIFRIHAENLYGISDPLV--SDSMKAKDRFRVPDAP 10518
Query: 912 DLQFV-EVTDVKVTIMWTPPESA---VTGYRVDV-IPVNLPGEHGQRLPISRNTFAEVTG 966
D V EVT + W P +T Y ++ ++ + PI T V
Sbjct: 10519 DQPIVTEVTKDSALVTWNKPHDGGKPITNYILEKRETMSKRWARVTKDPIHPYTKFRVPD 10578
Query: 967 LSPGVTYYFKVFAVSH------GRESKPLTAQQ-TTKLDAPTNLQFVNETDSTVLVRWTP 1019
L G Y F+V A + SKP+ A+ K P N + ++ T ++V + W P
Sbjct: 10579 LLEGCQYEFRVSAENEIGIGDPSPPSKPVFAKDPIAKPSPPVNPEAIDTTCNSVDLTWQP 10638
Query: 1020 PR----AQITGYRLTVGLTRRGQPRQYNVGPS---VSKYPLRNLQPASEYTVSLVAIKGN 1072
PR ++I GY + + R+ N P +KY + L+ Y ++A+
Sbjct: 10639 PRHDGGSKILGYIVEYQKVGDEEWRRANHTPESCPETKYKVTGLRDGQTYKFRVLAVNAA 10698
Query: 1073 QES-----PKATGVFTTLQPGSSIPPYNT---------EVTETTIVITWTPAPRIGFKLG 1118
ES P+ V L+P I N + + +I P P++ +K
Sbjct: 10699 GESDPAHVPEPVLVKDRLEPPELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKE 10758
Query: 1119 VRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPT 1178
R + +A +VT + + +Y++ V + + V+ PP
Sbjct: 10759 DRDAP-TKARIDVTPVGSKLEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDKPGPPR 10817
Query: 1179 NLHL-EANPDTGVLTVSWERSTTPD---ITGYRITTTPTNGQQGNSLEEVVHADQSSCTF 1234
+L + E D+ LT W+ IT Y + Q + L + + S
Sbjct: 10818 DLEVSEIRKDSCYLT--WKEPLDDGGSVITNYVVERRDVASAQWSPLSAT--SKKKSHFA 10873
Query: 1235 DNLSPGLEYNVSVYTVK--------DDKESVPISDTIIPEVPQLTDLSFVDITDSSIGLR 1286
+L+ G +Y V + + + D + P P DL VD+ + + L
Sbjct: 10874 KHLNEGNQYLFRVAAENQYGRGPFVETPKPIKALDPLHPPGPP-KDLHHVDVDKTEVSLV 10932
Query: 1287 WTPLN---SSTIIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLIN 1343
W + S I GY V EG + F + VTGL+ G Y V
Sbjct: 10933 WNKPDRDGGSPITGY--LVEYQEEGTQDWIKFKTVTNLECVVTGLQQGKTYRFRVKAENI 10990
Query: 1344 GGESAPTTL----TQQTAVPPPTDLRFTNI------GPDTMR----VTWAPPPSIDLTNF 1389
G P T Q+ VPP +L I T+R + P P+ T
Sbjct: 10991 VGLGLPDTTIPIECQEKLVPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWT-- 11048
Query: 1390 LVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGT-EYVVSVSSVYEQHESTPLRGRQKTG 1448
S +K +E + + S + L T EY ++VS+ + T
Sbjct: 11049 -TDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEYQITVSNA----AGSKTVAVHLTV 11103
Query: 1449 LD---SPTG-IDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSI 1504
LD PTG I+ D+T T+ W P+ I + E R V S +S
Sbjct: 11104 LDVPGPPTGPINILDVTPEHMTISWQPPKDDGGSPVINYIVEKQDTRKDTWGVVSSGSSK 11163
Query: 1505 T---LTNLTPGTEYVVSIVALN------GREESPLLIGQQSTVSDVPRDLEVVAATPTSL 1555
T + +L G EYV + A N + +P + + + P V T +
Sbjct: 11164 TKLKIPHLQKGCEYVFRVRAENKIGVGPPLDSTPTVAKHKFSPPSPPGKPVVTDITENAA 11223
Query: 1556 LISWDAP-----AVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVY 1610
+SW P + YY TG V + + K T GL G Y V+
Sbjct: 11224 TVSWTLPKSDGGSPITGYYMERREVTGKWVRVNKTPIADLKFRVT--GLYEGNTYEFRVF 11281
Query: 1611 AVTGRGDSPASSKPISINYRTEIDKPS---QMQVTDVQDNSISVKWL----PSSSPVTGY 1663
A G S S I I P ++ D + + W SP+ GY
Sbjct: 11282 AENLAGLSKPSPSSDPIKACRPIKPPGPPINPKLKDKSRETADLVWTKPLSDGGSPILGY 11341
Query: 1664 RVTTTPKNGPGPTKTKTAGPD----QTEMTIEGLQPTVEYVVSVYAQNPSGESQP 1714
V PG + D Q + GL EY + A N GE +P
Sbjct: 11342 VVEC---QKPGTAQWNRINKDELIRQCAFRVPGLIEGNEYRFRIKAANIVGEGEP 11393
Score = 83.2 bits (204), Expect = 3e-15
Identities = 182/840 (21%), Positives = 295/840 (35%), Gaps = 117/840 (13%)
Query: 1338 VITLIN--GGESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAPPPS---IDLTNFLVR 1392
V+T N G A T+ P +L+ ++ D V W PP ++ N+++
Sbjct: 11778 VVTATNTAGSFVAYATVNVLDKPGPVRNLKIVDVSSDRCTVCWDPPEDDGGCEIQNYILE 11837
Query: 1393 YSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQ---KTGL 1449
K + S + +T L+ G EY+ V + + P + KT
Sbjct: 11838 KCETKRMV-WSTYSATVLTPGTTVTRLIEGNEYIFRVRAENKIGTGPPTESKPVIAKTKY 11896
Query: 1450 DSPTGIDFSDITANS---FTVHWIAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRN 1502
D P D ++T S TV W P +ITGY + +H + ++
Sbjct: 11897 DKPGRPDPPEVTKVSKEEMTVVWNPPEYDGGKSITGYFLEKKEKHSTRWVPVNKSAIPER 11956
Query: 1503 SITLTNLTPGTEYVVSIVALN-------GREESPLLIGQQSTVSDVPRDLEVVAATPTSL 1555
+ + NL P EY + A N P++ P + VV T S+
Sbjct: 11957 RMKVQNLLPDHEYQFRVKAENEIGIGEPSLPSRPVVAKDPIEPPGPPTNFRVVDTTKHSI 12016
Query: 1556 LISWDAP-----AVTVRYYRITYGETGGNSPVQEFTVPGS-----KSTATISGLKPGVDY 1605
+ W P A + Y + SP + + + + T++ L +Y
Sbjct: 12017 TLGWGKPVYDGGAPIIGYVVEMRPKIADASPDEGWKRCNAAAQLVRKEFTVTSLDENQEY 12076
Query: 1606 TITVYAVTGRG-DSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYR 1664
V A G PA K E KP ++ D S++ L R
Sbjct: 12077 EFRVCAQNQVGIGRPAELK--------EAIKPKEILEPPEIDLDASMRKLVIVRAGCPIR 12128
Query: 1665 VTTTPKNGPGPTKT-KTAGPDQTEMTIE-GLQPTVEYVV------------SVYAQNPSG 1710
+ + P P T + G D + L T+ ++V S+ NP+G
Sbjct: 12129 LFAIVRGRPAPKVTWRKVGIDNVVRKGQVDLVDTMAFLVIPNSTRDDSGKYSLTLVNPAG 12188
Query: 1711 ESQPLVQTAVTNIDRP-KGLAFTDVDVDSIKIAWESPQG----QVSRYRVTYSSPEDGIH 1765
E V V + P L +DV S ++W P+ QV+ Y V +
Sbjct: 12189 EKAVFVNVRVLDTPGPVSDLKVSDVTKTSCHVSWAPPENDGGSQVTHYIVEKREADRKTW 12248
Query: 1766 ELFPAPDGEEDTAELQGLRPGSEYTVSVVALHD-------DMESQPLIGTQSTAIPAPTD 1818
P+ ++ + + L PG+EY V A+++ D+ L + P
Sbjct: 12249 STV-TPEVKKTSFHVTNLVPGNEYYFRVTAVNEYGPGVPTDVPKPVLASDPLSEPDPPRK 12307
Query: 1819 LKFTQVTPTSLSAQWTPP--------NVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVV 1870
L+ T++T S + W PP + +T YR P ++ E ++ D S +VV
Sbjct: 12308 LEVTEMTKNSATLAWLPPLRDGGAKIDGYITSYREEEQPADR---WTEYSVVKDLS-LVV 12363
Query: 1871 SGLMVATKYEVSVYALKDTLTSRP--AQGVVTTLENVSPPRRARVTDAT----------- 1917
+GL KY+ V A S P A+GV E + PP+ T
Sbjct: 12364 TGLKEGKKYKFRVAARNAVGVSLPREAEGVYEAKEQLLPPKILMPEQITIKAGKKLRIEA 12423
Query: 1918 ----ETTITISWRT-KTETITGFQVDAVPANGQTP--IQRTIKPDVRSYTITGLQPGTDY 1970
+ T W+ + E +T + A+ + I+ + D Y++T
Sbjct: 12424 HVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGYYSLTAENSSG-- 12481
Query: 1971 KIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYII 2026
D + VV+DA P ++ + SL SW P + IT YI+
Sbjct: 12482 -------TDTQKIKVVVMDAPGPPQPPFDISDIDADACSL--SWHIPLEDGGSNITNYIV 12532
Query: 2027 KYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELP 2086
+ + S V T + L PG EY V A SEPL K + P
Sbjct: 12533 E-KCDVSRGDWVTALASVTKTSCRVGKLIPGQEYIFRVRAENRFGISEPLTSPKMVAQFP 12591
Score = 80.1 bits (196), Expect = 2e-14
Identities = 310/1425 (21%), Positives = 524/1425 (36%), Gaps = 261/1425 (18%)
Query: 780 LLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPIT 839
++P ++Y++ V ++ G + A D PT+D IV+ + P+
Sbjct: 7853 VVPDKEYVLRVRAVNAIGVSEPSEISENVVAKDPDCKPTIDLETHDIIVIEGEKLSIPVP 7912
Query: 840 GYRIVYSPSV----EGSSTELNLPETANSVTLS---DLQPGVQYNITIYAV--EENQEST 890
+R V P+V +G + + T + +S ++ V+ + IY + E S
Sbjct: 7913 -FRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSA 7971
Query: 891 PVVIQQETTGTPRSDTVPSP-RDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGE 949
I + G +P P +D++ ++T + W PPE G + V E
Sbjct: 7972 TASINVKVIG------LPGPCKDIKASDITKSSCKLTWEPPE--FDGGTPILHYVLERRE 8023
Query: 950 HGQR--LPI--SRNTFA-EVTGLSPGVTYYFKVFAVSH--GRE----SKPLTAQQTTKL- 997
G+R +P+ N + V L P Y+F+V AV+ G E P+ AQ +
Sbjct: 8024 AGRRTYIPVMSGENKLSWTVKDLIPNGEYFFRVKAVNKVGGGEYIELKNPVIAQDPKQPP 8083
Query: 998 DAPTNLQFVNETDSTVLVRWTPPR----AQITGY---RLTVGLTRRGQPRQYNVGPSVSK 1050
D P +++ N T + + W PP ++I GY ++ G R + ++ V +
Sbjct: 8084 DPPVDVEVHNPTAEAMTITWKPPLYDGGSKIMGYIIEKIAKGEERWKRCNEHLV--PILT 8141
Query: 1051 YPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPA 1110
Y + L+ EY + A A G+ +P + PP T + A
Sbjct: 8142 YTAKGLEEGKEYQFRVRA-------ENAAGIS---EPSRATPP--------TKAVDPIDA 8183
Query: 1111 PRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVL--RDGQERDAPIVN 1168
P++ + + +G E + S SGS P + ++ V+ + ++R AP+V
Sbjct: 8184 PKVILRTSLEVKRGDEIALDA-SISGSPY-----PTITWIKDENVIVPEEIKKRAAPLVR 8237
Query: 1169 KVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHAD 1228
+ + L P T L++ N ++G S V
Sbjct: 8238 RRKGEVQEEEPFVL---PLTQRLSID-------------------NSKKGESQLRVR--- 8272
Query: 1229 QSSCTFDNLSPGLEYNVSVYTVKDDK--ESVPISDTIIPEVPQLTDLSFVDITDSSIGLR 1286
D+L P ++ + + V++D P + +++ + F DI +S+ +
Sbjct: 8273 ------DSLRP--DHGLYMIKVENDHGIAKAPCTVSVLDTPGPPINFVFEDIRKTSVLCK 8324
Query: 1287 WTPL---NSSTIIGYRITVVAAGEGIPIFEDFVDSSV---GYYTVTGLEPGIDYDISVIT 1340
W P S II Y T+ + P E V +S Y+VT L G +Y V
Sbjct: 8325 WEPPLDDGGSEIINY--TLEKKDKTKPDSEWIVVTSTLRHCKYSVTKLIEGKEYLFRVRA 8382
Query: 1341 LINGGESAPTTLTQQTAVPP------PTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYS 1394
G P A P P ++ ++M V W P D + ++ Y
Sbjct: 8383 ENRFGPGPPCVSKPLVAKDPFGPPDAPDKPIVEDVTSNSMLVKWNEPK--DNGSPILGYW 8440
Query: 1395 PVKNEEDVAELS-ISPSDNAVVLTN---LLPGTEYVVSVSSVYEQHESTPLR----GRQK 1446
K E + S ++ S + N LL G YV V + ++ + P + K
Sbjct: 8441 LEKREVNSTHWSRVNKSLLNALKANVDGLLEGLTYVFRVCA---ENAAGPGKFSPPSDPK 8497
Query: 1447 TGLD--SPTGIDFSDITANSFT---VHWIAPR----ATITGYRIRHHPEHFSGRPREDRV 1497
T D SP G +T S T + W P I GY + + R
Sbjct: 8498 TAHDPISPPGPPIPRVTDTSSTTIELEWEPPAFNGGGEIVGYFVDKQLVGTNEWSRCTEK 8557
Query: 1498 PHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLI 1557
T+ + G +Y + + A+N E P Q TV++ P++ A + +
Sbjct: 8558 MIKVRQYTVKEIREGADYKLRVSAVNAAGEGPPGETQPVTVAE-PQE---PPAVELDVSV 8613
Query: 1558 SWDAPAVTVRYYRITYGETGGNSPVQEFTVP--------------GSKSTATISGL--KP 1601
+ + RI TG P + +T G+KS I K
Sbjct: 8614 KGGIQIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKDRVVIDNVGTKSELIIKDALRKD 8673
Query: 1602 GVDYTITVYAVTGRGDSPA------------SSKPISINYRTEIDKPSQMQVTDVQDNSI 1649
Y IT G + A KP+ N K + +D +D+
Sbjct: 8674 HGRYVITATNSCGSKFAAARVEVFDVPGPVLDLKPVVTNR-----KMCLLNWSDPEDDG- 8727
Query: 1650 SVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPS 1709
S +TG+ + K+ T + ++++ I GL EY V A+N
Sbjct: 8728 -------GSEITGFIIER--KDAKMHTWRQPIETERSKCDITGLLEGQEYKFRVIAKNKF 8778
Query: 1710 GESQPLVQTAVTNID------RPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDG 1763
G P+ + +D P+ L +T+ +I + W+ P R SP G
Sbjct: 8779 GCGPPVEIGPILAVDPLGPPTSPERLTYTERTKSTITLDWKEP-------RSNGGSPIQG 8831
Query: 1764 I---HELFPAPDGEEDTAEL--------QGLRPGSEYTVSVVALHDDMESQPLIGTQSTA 1812
PD E L + L Y V A+++ ES+P +
Sbjct: 8832 YIIEKRRHDKPDFERVNKRLCPTTSFLVENLDEHQMYEFRVKAVNEIGESEP-------S 8884
Query: 1813 IPAPTDLKFTQVTPT---SLSAQWTPPNVQLTGYRVRVTPKEKTG-PMKEINLAPDSSSV 1868
+P ++ +V PT LS + V+ G V + P + TG PM +I + + + +
Sbjct: 8885 LPLNVVIQDDEVPPTIKLRLSVRGDTIKVK-AGEPVHI-PADVTGLPMPKIEWSKNETVI 8942
Query: 1869 VV-SGLMVATKYEVS-------------VYALKDTLTSRPAQGVVTTLENV--------S 1906
+ + TK EVS V K T T + + + NV S
Sbjct: 8943 EKPTDALQITKEEVSRSEAKTELSIPKAVREDKGTYTVTASNRLGSVFRNVHVEVYDRPS 9002
Query: 1907 PPRRARVTDATETTITISWRTKTET----ITGFQVDAVPANGQTPIQRTIKPDV--RSYT 1960
PPR VTD + ++W + IT + +D A+ + + + Y
Sbjct: 9003 PPRNLAVTDIKAESCYLTWDAPLDNGGSEITHYVIDKRDASRKKAEWEEVTNTAVEKRYG 9062
Query: 1961 ITGLQPGTDYKIYL-----YTLNDNARSSPVVI-DASTAIDAPSNLRFLATTPNSLLVSW 2014
I L P Y+ + Y ++D +S VVI D P + LA T S+LVSW
Sbjct: 9063 IWKLIPNGQYEFRVRAVNKYGISDECKSDKVVIQDPYRLPGPPGKPKVLARTKGSMLVSW 9122
Query: 2015 QPP----RARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLE 2055
PP + ITGY ++ + GSP V R +T+ + G+E
Sbjct: 9123 TPPLDNGGSPITGYWLEKREEGSPYWSRV--SRAPITKVGLKGVE 9165
Score = 78.2 bits (191), Expect = 9e-14
Identities = 286/1430 (20%), Positives = 494/1430 (34%), Gaps = 241/1430 (16%)
Query: 690 QEVTRFDFTTTSTST---------------PVTSNTVTGET-------------TPFSPL 721
++ R +F TT+TST P+T+ + GE P P+
Sbjct: 14610 KQTQRVNFETTATSTILNINECVRSDSGPYPLTARNIVGEVGDVITIQVHDIPGPPTGPI 14669
Query: 722 VATSESVTEITASSFVVSWVSASD----TVSGFRVEYELSEEGDEPQYLDLPSTA--TSV 775
E+++ SW + +S + VE + D +++L +T T+
Sbjct: 14670 -----KFDEVSSDFVTFSWDPPENDGGVPISNYVVE---MRQTDSTTWVELATTVIRTTY 14721
Query: 776 NIPDLLPGRKY-----IVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVR 830
L G +Y N Y + + I++ P P P V V S+ +
Sbjct: 14722 KATRLTTGLEYQFRVKAQNRYGVGPGITSACIVANYPFKVPGPPGTPQVTAVTKDSMTIS 14781
Query: 831 WSRP----QAPITGYRIVYSPSVEGSSTELNLPETANSVTL-------SDLQPGVQYNIT 879
W P +PI GY VE L +T + + S L G+ Y
Sbjct: 14782 WHEPLSDGGSPILGYH------VERKERNGILWQTVSKALVPGNIFKSSGLTDGIAYEFR 14835
Query: 880 IYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESA----VT 935
+ A +S P + D P L +T VT+ W PE +T
Sbjct: 14836 VIAENMAGKSKPSKPSEPMLALDPIDPPGKPVPL---NITRHTVTLKWAKPEYTGGFKIT 14892
Query: 936 GYRVDVIPVNLPGEHGQRLPIS---RNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQ 992
Y V+ +LP + S N F V+GL+ Y F+V A + P +
Sbjct: 14893 SYIVE--KRDLPNGRWLKANFSNILENEFT-VSGLTEDAAYEFRVIAKNAAGAISPPSEP 14949
Query: 993 QTT-----KLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQP-RQYNVGP 1046
++AP V D+ +L +RL ++ R P +++
Sbjct: 14950 SDAITCRDDVEAPKIKVDVKFKDTVILKAG-------EAFRLEADVSGRPPPTMEWSKDG 15002
Query: 1047 SVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSI-------------PP 1093
+ + ++++ +LV K + T PG PP
Sbjct: 15003 KELEGTAKLEIKIADFSTNLVN-KDSTRRDSGAYTLTATNPGGFAKHIFNVKVLDRPGPP 15061
Query: 1094 YN----TEVTETTIVITW-TPAPRIGFKLGVRPSQGGEAPREVTSDSGSIV------VSG 1142
TEVT V++W P G K+ Q E R ++ S V V+
Sbjct: 15062 EGPLAVTEVTSEKCVLSWFPPLDDGGAKIDHYIVQKRETSRLAWTNVASEVQVTKLKVTK 15121
Query: 1143 LTPGVEYVYTIQVLRD---GQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLT-----VS 1194
L G EY++ + + G+ ++ V V P PP NP+ +T V
Sbjct: 15122 LLKGNEYIFRVMAVNKYGVGEPLESEPV-LAVNPYGPPDP---PKNPEVTTITKDSMVVC 15177
Query: 1195 W---ERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVK 1251
W + +I Y + GQ+ + D L+ G EY +
Sbjct: 15178 WGHPDSDGGSEIINYIVERRDKAGQRWIKCNKKTLTD-LRYKVSGLTEGHEYEFRIMAEN 15236
Query: 1252 DDKESVP--------ISDTIIPEVPQLTDLSFVDITDSSIGLRWT-PL--NSSTIIGYRI 1300
S P DT+ P + +D + SSI + W P+ S I GY +
Sbjct: 15237 AAGISAPSPTSPFYKACDTVFKPGPP-GNPRVLDTSRSSISIAWNKPIYDGGSEITGYMV 15295
Query: 1301 TVVAAGEG-IPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAP-----TTLTQ 1354
+ E I YT+TGL +Y I + + + G P T +
Sbjct: 15296 EIALPEEDEWQIVTPPAGLKATSYTITGLTENQEYKIRIYAMNSEGLGEPALVPGTPKAE 15355
Query: 1355 QTAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNE------------EDV 1402
+PP +L D +V +I L + P+K E +
Sbjct: 15356 DRMLPPEIEL-----DADLRKVV-----TIRACCTLRLFVPIKGRPAPEVKWARDHGESL 15405
Query: 1403 AELSISPSDNAVVL----TNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFS 1458
+ SI + + +L N +Y+++V + +S + R P +
Sbjct: 15406 DKASIESTSSYTLLIVGNVNRFDSGKYILTVEN-SSGSKSAFVNVRVLDTPGPPQDLKVK 15464
Query: 1459 DITANSFTVHWIAPRATITGYRIRHH--PEHFSGRPREDRVPHS--RNSITLTNLTPGTE 1514
++T S T+ W P G +I+++ + S R V + + S + L G
Sbjct: 15465 EVTKTSVTLTWDPPLLD-GGSKIKNYIVEKRESTRKAYSTVATNCHKTSWKVDQLQEGCS 15523
Query: 1515 YVVSIVALN----GREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAP----AVTV 1566
Y ++A N G + S P + ++ T S+ +SW+ P +
Sbjct: 15524 YYFRVLAENEYGIGLPAETAESVKASERPLPPGKITLMDVTRNSVSLSWEKPEHDGGSRI 15583
Query: 1567 RYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPIS 1626
Y + G + TV + ATI+GL G +Y+ V A +G S +
Sbjct: 15584 LGYIVEMQTKGSDKWATCATV--KVTEATITGLIQGEEYSFRVSAQNEKGISDPRQLSVP 15641
Query: 1627 INYRTEIDKP------SQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKT 1680
+ + + P + V +D + V ++ +P + P +T
Sbjct: 15642 VIAKDLVIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLK-----QTTR 15696
Query: 1681 AGPDQTE----MTIEGL--QPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRP----KGLA 1730
+ TE +TI+ + YVV + N +GE+ + V +D+P +
Sbjct: 15697 VNAESTENNSLLTIKDACREDVGHYVVKL--TNSAGEAIETLNVIV--LDKPGPPTGPVK 15752
Query: 1731 FTDVDVDSIKIAWESPQ----GQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPG 1786
+V DSI ++W P+ ++ Y V ++ A T + L+ G
Sbjct: 15753 MDEVTADSITLSWGPPKYDGGSSINNYIVEKRDTSTTTWQIVSATVA-RTTIKACRLKTG 15811
Query: 1787 SEYTVSVVALH-----DDMESQPLIGTQSTAIPAPTDLK-FTQVTPTSLSAQWTPP---- 1836
EY + A + + S+P + +P P T + S+ QW P
Sbjct: 15812 CEYQFRIAAENRYGKSTYLNSEPTVAQYPFKVPGPPGTPVVTLSSRDSMEVQWNEPISDG 15871
Query: 1837 NVQLTGYRVRVTPKEKTGPM-KEINLAP-DSSSVVVSGLMVATKYEVSVYALKDTLTSRP 1894
++ GY + KE+ + ++N P + +GL +YE V A +P
Sbjct: 15872 GSRVIGYHLE--RKERNSILWVKLNKTPIPQTKFKTTGLEEGVEYEFRVSAENIVGIGKP 15929
Query: 1895 AQ--GVVTTLENVSPPRRARVTDATETTITISWRTKT----ETITGFQVD 1938
++ + PP R T ++T+ W+ T ITG+ V+
Sbjct: 15930 SKVSECYVARDPCDPPGRPEAIIVTRNSVTLQWKKPTYDGGSKITGYIVE 15979
Score = 75.1 bits (183), Expect = 8e-13
Identities = 286/1351 (21%), Positives = 472/1351 (34%), Gaps = 234/1351 (17%)
Query: 797 GEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ----APITGYRIVYSPSVEGS 852
G +++ + P P D V ++ S + W P + IT Y +
Sbjct: 10799 GSKTVSVKVLVLDKPGPPRDLEVSEIRKDSCYLTWKEPLDDGGSVITNYVVERRDVASAQ 10858
Query: 853 STELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRD 912
+ L+ S L G QY + A + V + P+D
Sbjct: 10859 WSPLSATSKKKSHFAKHLNEGNQYLFRVAAENQYGRGPFVETPKPIKALDPLHPPGPPKD 10918
Query: 913 LQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPVNLPGEHGQRLPISRNTFAE----V 964
L V+V +V+++W P+ S +TGY V+ E G + I T V
Sbjct: 10919 LHHVDVDKTEVSLVWNKPDRDGGSPITGYLVEY------QEEGTQDWIKFKTVTNLECVV 10972
Query: 965 TGLSPGVTYYFKVFA---VSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPR 1021
TGL G TY F+V A V G + + KL P+ V + V+ T R
Sbjct: 10973 TGLQQGKTYRFRVKAENIVGLGLPDTTIPIECQEKLVPPSVELDVKLIEGLVVKAGTTVR 11032
Query: 1022 --AQITGYRL-TVGLTRRGQPRQYNVGPSV------SKYPLRNL--QPASEYTVSLVAIK 1070
A I G + T T G + + +V S ++N + EY +++
Sbjct: 11033 FPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEYQITV---- 11088
Query: 1071 GNQESPKATGVFTTLQ--PGSSIPPYNT-EVTETTIVITWTPAPRIGFKLGVRPSQGGEA 1127
N K V T+ PG P N +VT + I+W P P G +
Sbjct: 11089 SNAAGSKTVAVHLTVLDVPGPPTGPINILDVTPEHMTISWQP-----------PKDDGGS 11137
Query: 1128 P--------REVTSDSGSIVVSG----------LTPGVEYVYTIQV---LRDGQERDA-P 1165
P ++ D+ +V SG L G EYV+ ++ + G D+ P
Sbjct: 11138 PVINYIVEKQDTRKDTWGVVSSGSSKTKLKIPHLQKGCEYVFRVRAENKIGVGPPLDSTP 11197
Query: 1166 IVNK-VVTPLSPPTNLHLEANPDTGVLTVSWERSTTPD---ITGY------------RIT 1209
V K +P SPP + + TVSW + ITGY R+
Sbjct: 11198 TVAKHKFSPPSPPGK-PVVTDITENAATVSWTLPKSDGGSPITGYYMERREVTGKWVRVN 11256
Query: 1210 TTP--------TNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISD 1261
TP T +GN+ E V A+ NL+ + + S +K + PI
Sbjct: 11257 KTPIADLKFRVTGLYEGNTYEFRVFAE-------NLAGLSKPSPSSDPIKACR---PIKP 11306
Query: 1262 TIIPEVPQLTDLSFVDITDSSIGLRWT-PLNS--STIIGYRITVVAAG--EGIPIFEDFV 1316
P P+L D S + L WT PL+ S I+GY + G + I +D +
Sbjct: 11307 PGPPINPKLKDKS-----RETADLVWTKPLSDGGSPILGYVVECQKPGTAQWNRINKDEL 11361
Query: 1317 DSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAV-----PPPTDLRFTNIGP 1371
+ V GL G +Y + GE P L + PP +L T
Sbjct: 11362 IRQCAF-RVPGLIEGNEYRFRIKAANIVGEGEPRELAESVIAKDILHPPEVELDVTCRDV 11420
Query: 1372 DTMRVTWA----------PPPSIDLTN---FLVRYSPVKNEEDV--AELSISPSDNAVVL 1416
T+RV P P I T LVR V +D+ EL I + A
Sbjct: 11421 ITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRA--- 11477
Query: 1417 TNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSP---TGIDFSDITANSFTVHWIAPR 1473
+Y++S + + + + LD P + +++T + T+ W P
Sbjct: 11478 ----DHGKYIISAKNSSGHAQGSAI----VNVLDRPGPCQNLKVTNVTKENCTISWENPL 11529
Query: 1474 ----ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNG----- 1524
+ IT + + + + G R + NL EY + A N
Sbjct: 11530 DNGGSEITNFIVEYRKPNQKGWSIVASDVTKR--LIKANLLANNEYYFRVCAENKVGVGP 11587
Query: 1525 --REESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYG---ETGGN 1579
++P+L P +L + T + + W P ++Y G+
Sbjct: 11588 TIETKTPILAINPIDRPGEPENLHIADKGKTFVYLKWRRPDYDGGSPNLSYHVERRLKGS 11647
Query: 1580 SPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASS--KPISINYRTEIDKPS 1637
+ K T + + V+ I + V + + S K + + ++ KP
Sbjct: 11648 DDWERVHKGSIKETHYM--VDRCVENQIYEFRVQTKNEGGESDWVKTEEVVVKEDLQKP- 11704
Query: 1638 QMQVTDVQDNSIS-VKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMT------I 1690
V D +S V + + + R+ + P P T D T++T I
Sbjct: 11705 ------VLDLKLSGVLTVKAGDTI---RLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKI 11755
Query: 1691 EGLQPTVEYVVSVYAQNPSGE--------SQPLVQTAVTNI-DRP---KGLAFTDVDVDS 1738
+ + ++ ++ ++ G+ + V A N+ D+P + L DV D
Sbjct: 11756 DTRADSSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATVNVLDKPGPVRNLKIVDVSSDR 11815
Query: 1739 IKIAWESPQG----QVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSV- 1793
+ W+ P+ ++ Y + + + + A T + L G+EY V
Sbjct: 11816 CTVCWDPPEDDGGCEIQNYILEKCETKRMVWSTYSATVLTPGTTVTR-LIEGNEYIFRVR 11874
Query: 1794 ----VALHDDMESQPLIGTQSTAIPA-PTDLKFTQVTPTSLSAQWTPPNVQ----LTGYR 1844
+ ES+P+I P P + T+V+ ++ W PP +TGY
Sbjct: 11875 AENKIGTGPPTESKPVIAKTKYDKPGRPDPPEVTKVSKEEMTVVWNPPEYDGGKSITGYF 11934
Query: 1845 VRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKD------TLTSRPAQGV 1898
+ K T + A + V L+ +Y+ V A + +L SRP
Sbjct: 11935 LEKKEKHSTRWVPVNKSAIPERRMKVQNLLPDHEYQFRVKAENEIGIGEPSLPSRPVVAK 11994
Query: 1899 VTTLENVSPPRRARVTDATETTITISWRTKT----ETITGFQV-------DAVPANGQTP 1947
+E PP RV D T+ +IT+ W I G+ V DA P G
Sbjct: 11995 -DPIEPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAPIIGYVVEMRPKIADASPDEGWKR 12053
Query: 1948 IQRTIKPDVRSYTITGLQPGTDYKIYLYTLN 1978
+ + +T+T L +Y+ + N
Sbjct: 12054 CNAAAQLVRKEFTVTSLDENQEYEFRVCAQN 12084
Score = 71.2 bits (173), Expect = 1e-11
Identities = 350/1644 (21%), Positives = 556/1644 (33%), Gaps = 296/1644 (18%)
Query: 628 IQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISI 684
+ W +P+ S I+ Y++ R + W T + T++GL G Y ++ +
Sbjct: 10138 LTWFSPEDDGGSPITNYVIEKRESDRRA-WTPVTYTVTRQNATVQGLIQGKAYFFRIAAE 10196
Query: 685 QQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSAS 744
G F TS + + T P P V E+T ++ ++W
Sbjct: 10197 NSIGMGP-----FVETSEALVIREPI----TVPERP---EDLEVKEVTKNTVTLTWNPPK 10244
Query: 745 DTVSGFRVEYELSEE--GDEPQYLDLPSTATS--VNIPDLLPGRKYIVNVYQISEDGEQS 800
+ Y L G E + S + L G Y V ++ G+
Sbjct: 10245 YDGGSEIINYVLESRLIGTEKFHKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGK 10304
Query: 801 LILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPE 860
T T D PT+ + +R A Y P V E ++ E
Sbjct: 10305 PSFCTKPITCKDELAPPTLHLDFRDKLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLE 10364
Query: 861 TANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQET---TGTPRSDTVPSPRD----L 913
+ T P I A + VV++ T G + + V P +
Sbjct: 10365 --DDRTHIKTTPATLALEKIKAKRSDSGKYCVVVENSTGSRKGFCQVNVVDRPGPPVGPV 10422
Query: 914 QFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPGEHGQRLPI---SRNTFAEVTG 966
F EVT + I W PP S +T Y ++ V +P+ S T +V+
Sbjct: 10423 SFDEVTKDYMVISWKPPLDDGGSKITNYIIEKKEVG----KDVWMPVTSASAKTTCKVSK 10478
Query: 967 LSPGVTYYFKVFAVSHGRESKPLTAQQTTKLD------APTNLQFVNETDSTVLVRWTPP 1020
L G Y F++ A + S PL + D AP T + LV W P
Sbjct: 10479 LLEGKDYIFRIHAENLYGISDPLVSDSMKAKDRFRVPDAPDQPIVTEVTKDSALVTWNKP 10538
Query: 1021 R---AQITGYRLTVGLTRRGQPRQYNVGP--SVSKYPLRNLQPASEYTVSLVA---IKGN 1072
IT Y L T + + P +K+ + +L +Y + A I
Sbjct: 10539 HDGGKPITNYILEKRETMSKRWARVTKDPIHPYTKFRVPDLLEGCQYEFRVSAENEIGIG 10598
Query: 1073 QESPKATGVFTTLQPGSSIPPYNTEVTETT---IVITWTPAPRIGFKLGVRPSQGGEAPR 1129
SP + VF PP N E +TT + +TW P PR
Sbjct: 10599 DPSPPSKPVFAKDPIAKPSPPVNPEAIDTTCNSVDLTWQP------------------PR 10640
Query: 1130 EVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTG 1189
D GS ++ Y+ Q + D + R A N E+ P+T
Sbjct: 10641 H---DGGSKILG-------YIVEYQKVGDEEWRRA--------------NHTPESCPETK 10676
Query: 1190 VLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPG---LEYNVS 1246
T +R+ G+ + H + D L P L+ N++
Sbjct: 10677 YKVTGLRDGQTYK---FRVLAVNAAGES-----DPAHVPEPVLVKDRLEPPELILDANMA 10728
Query: 1247 VYTVKDDKESVPISDT-----IIPEVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGYRIT 1301
++ + + DT II VP F +T W + RI
Sbjct: 10729 ------REQHIKVGDTLRLSAIIKGVP------FPKVT-------WKKEDRDAPTKARID 10769
Query: 1302 VVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAVPPP 1361
V G + I + G Y++T P +SV L+ PP
Sbjct: 10770 VTPVGSKLEI-RNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDKPG------------PP 10816
Query: 1362 TDLRFTNIGPDTMRVTWAPPPSID---LTNFLVRYSPVKNEEDVAELSISPSDNAVVLTN 1418
DL + I D+ +TW P +TN++V V + + + LS + + +
Sbjct: 10817 RDLEVSEIRKDSCYLTWKEPLDDGGSVITNYVVERRDVASAQ-WSPLSATSKKKSHFAKH 10875
Query: 1419 LLPGTEYVVSVSSVYEQHESTPLRGRQKT--GLDS------PTGIDFSDITANSFTVHWI 1470
L G +Y+ V++ Q+ P K LD P + D+ ++ W
Sbjct: 10876 LNEGNQYLFRVAAE-NQYGRGPFVETPKPIKALDPLHPPGPPKDLHHVDVDKTEVSLVWN 10934
Query: 1471 APR----ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN--- 1523
P + ITGY + + E + V + +T L G Y + A N
Sbjct: 10935 KPDRDGGSPITGYLVEYQEEGTQDWIKFKTVTNLE--CVVTGLQQGKTYRFRVKAENIVG 10992
Query: 1524 -GREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPV 1582
G ++ + I Q + VP +E+ L++ TVR+ I G P
Sbjct: 10993 LGLPDTTIPIECQEKL--VPPSVELDVKLIEGLVVK---AGTTVRFPAIIRGVP---VPT 11044
Query: 1583 QEFTVPGSK---------------STATISGL--KPGVDYTITVYAVTGRGDSPASSKPI 1625
++T GS+ S TI + +Y ITV + A SK +
Sbjct: 11045 AKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEYQITV-------SNAAGSKTV 11097
Query: 1626 SINYRTEIDKPSQ----MQVTDVQDNSISVKWLP----SSSPVTGYRVTT--TPKNGPGP 1675
+++ T +D P + + DV +++ W P SPV Y V T K+ G
Sbjct: 11098 AVHL-TVLDVPGPPTGPINILDVTPEHMTISWQPPKDDGGSPVINYIVEKQDTRKDTWGV 11156
Query: 1676 TKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDR------PKGL 1729
++G +T++ I LQ EYV V A+N G PL T + P
Sbjct: 11157 V---SSGSSKTKLKIPHLQKGCEYVFRVRAENKIGVGPPLDSTPTVAKHKFSPPSPPGKP 11213
Query: 1730 AFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQ----GLRP 1785
TD+ ++ ++W P+ Y + + + + A+L+ GL
Sbjct: 11214 VVTDITENAATVSWTLPKSDGGSPITGYYMERREVTGKWVRVN-KTPIADLKFRVTGLYE 11272
Query: 1786 GSEYTVSVVALH------DDMESQPLIGTQSTAIPA-PTDLKFTQVTPTSLSAQWTPP-- 1836
G+ Y V A + S P+ + P P + K + + WT P
Sbjct: 11273 GNTYEFRVFAENLAGLSKPSPSSDPIKACRPIKPPGPPINPKLKDKSRETADLVWTKPLS 11332
Query: 1837 --NVQLTGYRVRVTPKEKTGPMKEINLAP--DSSSVVVSGLMVATKYEVSVYALKDTLTS 1892
+ GY V K T IN + V GL+ +Y + A
Sbjct: 11333 DGGSPILGYVVE-CQKPGTAQWNRINKDELIRQCAFRVPGLIEGNEYRFRIKAANIVGEG 11391
Query: 1893 RP---AQGVVTTLENVSPPR-------RARVTDATETTITISWRTK-------TETITG- 1934
P A+ V+ + + PP R +T TI I R K T T G
Sbjct: 11392 EPRELAESVIAK-DILHPPEVELDVTCRDVITVRVGQTIRILARVKGRPEPDITWTKEGK 11450
Query: 1935 -----FQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVID 1989
+VD + + +Q IK VR+ Y I + +A+ S +V
Sbjct: 11451 VLVREKRVDLIQDLPRVELQ--IKEAVRA-------DHGKYIISAKNSSGHAQGSAIV-- 11499
Query: 1990 ASTAIDAP---SNLRFLATTPNSLLVSWQPP----RARITGYIIKYEKPGSPPREVVPRP 2042
+D P NL+ T + +SW+ P + IT +I++Y KP +V
Sbjct: 11500 --NVLDRPGPCQNLKVTNVTKENCTISWENPLDNGGSEITNFIVEYRKPNQKGWSIV--- 11554
Query: 2043 RPGVTEATI-TGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELPQLVTLPHPNLHGPEI 2101
VT+ I L EY V A +N P I K P L P PE
Sbjct: 11555 ASDVTKRLIKANLLANNEYYFRVCA-ENKVGVGPTIETK----TPILAINPIDRPGEPEN 11609
Query: 2102 LDVPSTVQKTPFV--THPGYDTGN 2123
L + + ++ P YD G+
Sbjct: 11610 LHIADKGKTFVYLKWRRPDYDGGS 11633
Score = 67.8 bits (164), Expect = 1e-10
Identities = 172/864 (19%), Positives = 306/864 (35%), Gaps = 155/864 (17%)
Query: 1325 VTGLEPGIDYDISVITLINGGESAPT------TLTQQTAVPPPTDLRFTNIGPDTMRVTW 1378
VT L G +Y V + G P L T PPT L T++ ++M + W
Sbjct: 19447 VTKLLKGNEYIFRVTGVNKYGVGEPLESVAIKALDPFTVPSPPTSLEITSVTKESMTLCW 19506
Query: 1379 APPPS---IDLTNFLVRYSPVKNEEDVAELSISP-SDNAVVLTNLLPGTEYVVSV----- 1429
+ P S +++ +++ KN ++ P D V T L G EY V
Sbjct: 19507 SRPESDGGSEISGYIIERRE-KNSLRWVRVNKKPVYDLRVKSTGLREGCEYEYRVYAENA 19565
Query: 1430 SSVYEQHESTPL-RGRQKTGLDS-PTGIDFSDITANSFTVHWIAP----RATITGYRIRH 1483
+ + E++PL R L S P+ D + T+ W+ P A ITGY + +
Sbjct: 19566 AGLSLPSETSPLIRAEDPVFLPSPPSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEY 19625
Query: 1484 HPEHFSGRPREDRVPHSRNS-ITLTNLTPGTEYVVSIVALN-----------------GR 1525
+ + + R + T++ LT G EYV + ++N R
Sbjct: 19626 --KKSDDTDWKTSIQSLRGTEYTISGLTTGAEYVFRVKSVNKVGASDPSDSSDPQIAKER 19683
Query: 1526 EESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEF 1585
EE PL S++ + L V A ++ + + V + + + + + +
Sbjct: 19684 EEEPLF----DIDSEMRKTLIVKAGASFTMTVPFRGRPVP----NVLWSKPDTDLRTRAY 19735
Query: 1586 T-VPGSKSTATI--SGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVT 1642
S+++ TI + YT+T+ V A+S + + P+ + V
Sbjct: 19736 VDTTDSRTSLTIENANRNDSGKYTLTIQNVLS-----AASLTLVVKVLDTPGPPTNITVQ 19790
Query: 1643 DVQDNSISVKW-LPSS---SPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVE 1698
DV S + W +P + +PV Y + + T ++ + LQ
Sbjct: 19791 DVTKESAVLSWDVPENDGGAPVKNYHIEKREASKKAWVSV-TNNCNRLSYKVTNLQEGAI 19849
Query: 1699 YVVSVYAQNPSGESQPLVQTAVTNIDR----PKGLAFTDVDVDSIKIAWESPQGQVSRYR 1754
Y V +N G P I P+ L T + DS+ + W P+
Sbjct: 19850 YYFRVSGENEFGVGIPAETKEGVKITEKPSPPEKLGVTSISKDSVSLTWLKPEHDGGSRI 19909
Query: 1755 VTY--SSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTA 1812
V Y + E G + + GLR SEY V A E+Q
Sbjct: 19910 VHYVVEALEKGQKNWVKCAVAKSTHHVVSGLRENSEYFFRVFA-----ENQ-------AG 19957
Query: 1813 IPAPTDLKFTQVTPTSLSAQWTPPNVQL-----------TGYRVRVTPKEKTGPMKEINL 1861
+ P +L + P + Q PP + + G ++V P+ ++ L
Sbjct: 19958 LSDPREL----LLPVLIKEQLEPPEIDMKNFPSHTVYVRAGSNLKVDIPISGKPLPKVTL 20013
Query: 1862 APD----------SSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGV------VTTLENV 1905
+ D ++ + L + K V+ A + +T+ + G + L+
Sbjct: 20014 SRDGVPLKATMRFNTEITAENLTINLKESVTADAGRYEITAANSSGTTKAFINIVVLDRP 20073
Query: 1906 SPPR-RARVTDATETTITISWR---------------TKTETITGFQVDAVPANGQTPIQ 1949
PP ++D TE ++T+ W K ET T AV +
Sbjct: 20074 GPPTGPVVISDITEESVTLKWEPPKYDGGSQVTNYILLKRETST-----AVWTEVSATVA 20128
Query: 1950 RTIKPDVRSYTITGLQPGTDYKIYL-----YTLNDNARSSPVVIDASTAIDAPSNLRFLA 2004
RT+ + L G +Y+ + + ++D+ S+ V + P + ++
Sbjct: 20129 RTM------MKVMKLTTGEEYQFRIKAENRFGISDHIDSACVTVKLPYTTPGPPSTPWVT 20182
Query: 2005 -TTPNSLLVSWQPP----RARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTE 2059
T S+ V W P + + GY ++ + S + + T +T + G
Sbjct: 20183 NVTRESITVGWHEPVSNGGSAVVGYHLEMKDRNSILWQKANKLVIRTTHFKVTTISAGLI 20242
Query: 2060 YTIYVIAL------KNNQKSEPLI 2077
Y V A K + SEP++
Sbjct: 20243 YEFRVYAENAAGVGKPSHPSEPVL 20266
Score = 65.1 bits (157), Expect = 8e-10
Identities = 102/477 (21%), Positives = 189/477 (39%), Gaps = 56/477 (11%)
Query: 628 IQWNAPQP---SHISKYILRWRPKNSVGRWKEAT-IPGHLNSYTIKGLKPGVVYEGQLIS 683
+ W P+ S ++ YI+ R + RW +P + Y GL G+ YE ++ +
Sbjct: 23453 LTWYPPEDDGGSQVTGYIVE-RKEVRADRWVRVNKVPVTMTRYRSTGLTEGLEYEHRVTA 23511
Query: 684 IQQYGHQEVTRFDFTTTSTSTPVTS-NTVTGETTPFSPLVATSESVTEITASSFVVSWVS 742
I G + +R S P+ + + + P +P VT+ T +S ++W
Sbjct: 23512 INARGSGKPSR-------PSKPIVAMDPIAPPGKPQNP------RVTDTTRTSVSLAWSV 23558
Query: 743 ASDT----VSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDG- 797
D V+G+ +E + ++ + + P+ + L G +Y V + G
Sbjct: 23559 PEDEGGSKVTGYLIEMQKVDQHEWTKCNTTPTKIREYTLTHLPQGAEYRFRVLACNAGGP 23618
Query: 798 -EQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWS---RPQAPITGYRI-VYSPSVEGS 852
E + + T + T PD +D+ I VR R PI G + + EG
Sbjct: 23619 GEPAEVPGTVKVTEMLEYPDYELDERYQEGIFVRQGGVIRLTIPIKGKPFPICKWTKEGQ 23678
Query: 853 STE----LNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVP 908
+ ET + + + G + +E V I+ G+P S P
Sbjct: 23679 DISKRAMIATSETHTELVIKEADRGDSGTYDL-VLENKCGKKAVYIKVRVIGSPNSPEGP 23737
Query: 909 SPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEV 964
L++ ++ V + W PP + + GY ++ V + + R T V
Sbjct: 23738 ----LEYDDIQVRSVRVSWRPPADDGGADILGYILERREVPKAAWYTIDSRV-RGTSLVV 23792
Query: 965 TGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTN--------LQFVNETDSTVLVR 1016
GL V Y+F+V A + SKPL +++ P N + ++ T S+V +
Sbjct: 23793 KGLKENVEYHFRVSAENQFGISKPLKSEEPVTPKTPLNPPEPPSNPPEVLDVTKSSVSLS 23852
Query: 1017 WTPPR----AQITGYRLTVGLTRRGQPRQYN-VGPSVSKYPLRNLQPASEYTVSLVA 1068
W+ P+ +++TGY + T + ++N + + Y + L P +EY ++A
Sbjct: 23853 WSRPKDDGGSRVTGYYIERKETSTDKWVRHNKTQITTTMYTVTGLVPDAEYQFRIIA 23909
Score = 60.1 bits (144), Expect = 3e-08
Identities = 177/822 (21%), Positives = 289/822 (35%), Gaps = 149/822 (18%)
Query: 1360 PPTDLRFTNIGPDTMRVTWAPPPS---IDLTNFLVRYSPVKNEEDVAELSISPSDNAVVL 1416
P +L T + + W P + + ++V +K + V + S V
Sbjct: 6595 PVRNLEVTETFDGEVSLAWEEPLTDGGSKIIGYVVERRDIKRKTWVLATDRAESCEFTVT 6654
Query: 1417 TNLLPGTEYVVSVSS-----VYEQHES-TPLRGRQKTGLDSPT-GIDFSDITANSFTVHW 1469
G EY+ VS+ E E+ P+ R K + P + +D+ ++ W
Sbjct: 6655 GLQKGGVEYLFRVSARNRVGTGEPVETDNPVEARSKYDVPGPPLNVTITDVNRFGVSLTW 6714
Query: 1470 IAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGR 1525
P A IT Y I + V S T+T++ G EY + R
Sbjct: 6715 EPPEYDGGAEITNYVIELRDKTSIRWDTAMTVRAEDLSATVTDVVEGQEYSFRV-----R 6769
Query: 1526 EESPLLIGQQSTVSDV------------PRDLEVVAATPTSLLISWDAP----AVTVRYY 1569
++ + +G+ S + P +L T +S+ + W+ P + Y
Sbjct: 6770 AQNRIGVGKPSAATPFVKVADPIERPSPPVNLTSSDQTQSSVQLKWEPPLKDGGSPILGY 6829
Query: 1570 RITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINY 1629
I E G ++ ++ + T ++GL+ G Y V A G S S +
Sbjct: 6830 IIERCEEGKDNWIRCNMKLVPELTYKVTGLEKGNKYLYRVSAENKAGVSDPSEILGPLTA 6889
Query: 1630 RTEIDKPSQMQVTDVQDNSISVKWLPSSS--PVTGYRVTTTPKNGPGPTKTKTAGPDQTE 1687
+P+ M ++ +D + P + P TGY P PT T G E
Sbjct: 6890 DDAFVEPT-MDLSAFKDGLEVIVPNPITILVPSTGY---------PRPTATWCFGDKVLE 6939
Query: 1688 ----MTIEGLQPTVEYVVSVYAQNPSG----ESQPLVQTAVTNID--------RPKGLAF 1731
+ ++ L E V+S ++ G + + V+T ID PK L F
Sbjct: 6940 TGDRVKMKTLSAYAELVISPSERSDKGIYTLKLENRVKTISGEIDVNVIARPSAPKELKF 6999
Query: 1732 TDVDVDSIKIAWESPQ----GQVSRY--------RVTYSSPEDGIHEL-FPAPDGEEDTA 1778
D+ DS+ + WE P ++ Y R T++ D + +L F PD
Sbjct: 7000 GDITKDSVHLTWEPPDDDGGSPLTGYVVEKREVSRKTWTKVMDFVTDLEFTVPD------ 7053
Query: 1779 ELQGLRPGSEYTVSVVALHDDMESQPL-------IGTQSTAIPAPTDLKFTQVTPTSLSA 1831
L G EY V A + +P + T +T P ++K+ T S+
Sbjct: 7054 ----LVQGKEYLFKVCARNKCGPGEPAYVDEPVNMSTPATVPDPPENVKWRDRTANSIFL 7109
Query: 1832 QWTPP----NVQLTGYRVRVTPKEKTGPMKEINLAPD--SSSVVVSGLMVATKYEVSVYA 1885
W PP ++ GY V P+ G K + + + V+GL Y V A
Sbjct: 7110 TWDPPKNDGGSRIKGYIVERCPR---GSDKWVACGEPVAETKMEVTGLEEGKWYAYRVKA 7166
Query: 1886 LKDTLTSRPAQGVVTTLENVSPPRRARVTDATETT-----------ITISWRTKTE---T 1931
L S+P++ P + D E +T+ TK E T
Sbjct: 7167 LNRQGASKPSR----------PTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPAT 7216
Query: 1932 ITGFQVDAVPANGQTPIQRTIKPDVR----------SYTITGLQPGTDYKIYLYTLNDNA 1981
+TG P T +K D R + TI + + +N
Sbjct: 7217 VTG---KPEPKITWTKADMILKQDKRITIENVPKKSTVTIVDSKRSDTGTYIIEAVNVCG 7273
Query: 1982 RSSPVV-IDASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPR 2036
R++ VV ++ P+ T S L++W PPR ++IT Y+++ S
Sbjct: 7274 RATAVVEVNVLDKPGPPAAFDITDVTNESCLLTWNPPRDDGGSKITNYVVERRATDS--- 7330
Query: 2037 EVVPRPRPGV--TEATITGLEPGTEYTIYVIALKNNQKSEPL 2076
EV + V T T L P EY V A EP+
Sbjct: 7331 EVWHKLSSTVKDTNFKATKLIPNKEYIFRVAAENMYGVGEPV 7372
Score = 58.9 bits (141), Expect = 6e-08
Identities = 325/1703 (19%), Positives = 588/1703 (34%), Gaps = 267/1703 (15%)
Query: 611 PVEVFITETPSQP-----------NSHPIQWNAPQPS---HISKYILRWRPKNSVGRWKE 656
P+ V PS+P +S + W+ P+ + I+ Y + R + S WK
Sbjct: 21151 PITVITLGPPSKPKGPIRFDEIKADSVILSWDVPEDNGGGEITCYSIEKR-ETSQTNWKM 21209
Query: 657 ATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETT 716
++ + L Y+ ++ + +YG S P+ S+ + +
Sbjct: 21210 VCSSVARTTFKVPNLVKDAEYQFRVRAENRYG-------------VSQPLVSSIIVAKHQ 21256
Query: 717 PFSPLVATSESVTEITASSFVVSW----VSASDTVSGFRVEYELSEEGDEPQYLDLPSTA 772
P + +T+ ++W V+GF VE + + P +
Sbjct: 21257 FRIPGPPGKPVIYNVTSDGMSLTWDAPVYDGGSEVTGFHVEKKERNSILWQKVNTSPISG 21316
Query: 773 TSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDP--TVDQVDDT--SIV 828
L+ G Y VY + G S S+ T +P DP T D +D T +I
Sbjct: 21317 REYRATGLVEGLDYQFRVYAENSAGLSSPS-DPSKFTLAVSPVDPPGTPDYIDVTRETIT 21375
Query: 829 VRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETAN-SVTLSDLQPGVQYNITIYA- 882
++W+ P + I GY I E N + + T++ L PG +Y I A
Sbjct: 21376 LKWNPPLRDGGSKIVGYSIEKRQGNE-RWVRCNFTDVSECQYTVTGLSPGDRYEFRIIAR 21434
Query: 883 -----VEENQESTPVVIQQETTGTPRSDTVPSPRD---LQFVEVTDVKVTIMWTPPESAV 934
+ +S+ +++ ++ P + P D ++ E +K + P V
Sbjct: 21435 NAVGTISPPSQSSGIIMTRDENVPPIVEFGPEYFDGLIIKSGESLRIKALVQGRPVPR-V 21493
Query: 935 TGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFK--------VFAVSHGRES 986
T ++ V I + E+T + + + + V+ V S
Sbjct: 21494 TWFKDGV-------------EIEKRMNMEITDVLGSTSLFVRDATRDHRGVYTVEAKNAS 21540
Query: 987 KPLTAQQTTKL-DAPTN----LQFVNETDSTVLVRWTPPR----AQITGYRLTVGLTRRG 1037
A+ K+ D P ++F N T + + W P A IT Y + T R
Sbjct: 21541 GSAKAEIKVKVQDTPGKVVGPIRFTNITGEKMTLWWDAPLNDGCAPITHYIIEKRETSRL 21600
Query: 1038 QPRQYNVGPSVSKYPLRNLQPASEYTVSLVAI------KGNQESPKATGVFTTLQPGSSI 1091
Y L +EY + A+ + P + T+ I
Sbjct: 21601 AWALIEDKCEAQSYTAIKLINGNEYQFRVSAVNKFGVGRPLDSDPVVAQIQYTVPDAPGI 21660
Query: 1092 PPYNTEVTETTIVITWTPAPRIG------FKLGVRPSQGGEAPREVTSDSGS---IVVSG 1142
P + +T +I +TW G + L R + + ++ S V+G
Sbjct: 21661 PE-PSNITGNSITLTWARPESDGGSEIQQYILERREKKSTRWVKVISKRPISETRFKVTG 21719
Query: 1143 LTPGVEYVYTIQVLRDGQERDAPIVNKVVT---PLSPPTNLHLEANPDTGVLTVSWERST 1199
LT G EY + + A +++++ P++PP + DT TVS E S
Sbjct: 21720 LTEGNEYEFHVMAENAAGVGPASGISRLIKCREPVNPPGPPTVVKVTDTSKTTVSLEWSK 21779
Query: 1200 TP-----DITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKD-- 1252
+I GY I + + + ++ T +L G EY V +
Sbjct: 21780 PVFDGGMEIIGYIIEMCKADLGDWHKVNAEACV-KTRYTVTDLQAGEEYKFRVSAINGAG 21838
Query: 1253 DKESVPISDTI-------IPEVPQLTDLSFVDITDSSIGLR--------------WTPLN 1291
+S ++ TI PE+ + + + +R W+ +
Sbjct: 21839 KGDSCEVTGTIKAVDRLTAPELDIDANFKQTHVVRAGASIRLFIAYQGRPTPTAVWSKPD 21898
Query: 1292 SSTIIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTT 1351
S+ + I + + + E+ + G YT+T + +G +S T
Sbjct: 21899 SNLSLRADIHTTDSFSTLTV-ENCNRNDAGKYTLT------------VENNSGSKSITFT 21945
Query: 1352 LTQQTAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAE---LSIS 1408
+ PP + F ++ + + W P +D + Y K E +S
Sbjct: 21946 VKVLDTPGPPGPITFKDVTRGSATLMW-DAPLLDGGARIHHYVVEKREASRRSWQVISEK 22004
Query: 1409 PSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDS----PTGIDFSDITANS 1464
+ + +L G Y VS+V E P + P +D D + +S
Sbjct: 22005 CTRQIFKVNDLAEGVPYYFRVSAVNEYGVGEPYEMPEPIVATEQPAPPRRLDVVDTSKSS 22064
Query: 1465 FTVHWIAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRN-SITLTNLTPGTEYVVSI 1519
+ W+ P + ITGY + + G H++ + T+ L TEY +
Sbjct: 22065 AVLAWLKPDHDGGSRITGYLLEMRQK---GSDFWVEAGHTKQLTFTVERLVEKTEYEFRV 22121
Query: 1520 VALNGREESPLLIGQQSTVSDVPR-----DLEVV--------AATPTSL---LISWDAPA 1563
A N S S + P+ DL + A +P ++ + AP
Sbjct: 22122 KAKNDAGYSEPREAFSSVIIKEPQIEPTADLTGITNQLITCKAGSPFTIDVPISGRPAPK 22181
Query: 1564 VTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVD--YTITVYAVTGRGDSPAS 1621
VT + + ET S T ++T T+ G Y +T+ ++ A
Sbjct: 22182 VTWKLEEMRLKETDRVS----ITTTKDRTTLTVKDSMRGDSGRYFLTL-------ENTAG 22230
Query: 1622 SKPISINYRTEIDKPSQM----QVTDVQDNSISVKWLP----SSSPVTGYRVTTTPKNGP 1673
K S+ I +P + +V+ V S + W + +T Y + ++G
Sbjct: 22231 VKTFSVTV-VVIGRPGPVTGPIEVSSVSAESCVLSWGEPKDGGGTEITNY-IVEKRESGT 22288
Query: 1674 GPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAV------TNIDRPK 1727
+ + +T++ + L +EY V ++N G S+PL + P
Sbjct: 22289 TAWQLVNSSVKRTQIKVTHLTKYMEYSFRVSSENRFGVSKPLESAPIIAEHPFVPPSAPT 22348
Query: 1728 GLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGE----EDTAELQGL 1783
V +++ I WE P + Y + + + + + E ++ GL
Sbjct: 22349 RPEVYHVSANAMSIRWEEPYHDGGSKIIGYWVEKKERNTILWVKENKVPCLECNYKVTGL 22408
Query: 1784 RPGSEYTVSVVALH------DDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPP- 1836
G EY AL+ S+P++ + AP + T VT +++S W+ P
Sbjct: 22409 VEGLEYQFRTYALNAAGVSKASEASRPIMA--QNPVDAPGRPEVTDVTRSTVSLIWSAPA 22466
Query: 1837 ---NVQLTGYRVRVTPKEKTGP---MKEINLAPDSSSVVVSGLMVATKYEVSVYALKDT- 1889
++ GY + P + G +K + V+ L YE V A
Sbjct: 22467 YDGGSKVVGYIIERKPVSEVGDGRWLKCNYTIVSDNFFTVTALSEGDTYEFRVLAKNAAG 22526
Query: 1890 LTSRPAQ--GVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVP------ 1941
+ S+ ++ G VT + +PP+ DA ++ R ++ + V P
Sbjct: 22527 VISKGSESTGPVTCRDEYAPPKAE--LDARLHGDLVTIRAGSDLVLDAAVGGKPEPKIIW 22584
Query: 1942 ANGQTPIQRTIKPDV-----RSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDA 1996
G + K + R+ + +D Y T+ NA + V +D+
Sbjct: 22585 TKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSGKYTLTVK-NASGTKAVSVMVKVLDS 22643
Query: 1997 P---SNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREVVPRPRPGVTEA 2049
P L T ++W P+ A IT YI++ + +V P ++
Sbjct: 22644 PGPCGKLTVSRVTQEKCTLAWSLPQEDGGAEITHYIVERRETSRLNWVIVEGECPTLS-Y 22702
Query: 2050 TITGLEPGTEYTIYVIALKN-----NQKSEPLIGRKKTDELPQLVTLPHPNLHGPEILDV 2104
+T L EY V A+ +SEP++ R T+P P P I +
Sbjct: 22703 VVTRLIKNNEYIFRVRAVNKYGPGVPVESEPIVARNS-------FTIPSP----PGIPEE 22751
Query: 2105 PSTVQKTPFV--THPGYDTGNGI 2125
T ++ + T P D GN I
Sbjct: 22752 VGTGKEHIIIQWTKPESDGGNEI 22774
Score = 55.5 bits (132), Expect = 7e-07
Identities = 128/535 (23%), Positives = 202/535 (37%), Gaps = 90/535 (16%)
Query: 593 GIGEWHCQPLQTYPSSSGPVEVFITETPSQP-------NSHPIQWNAPQ---PSHISKYI 642
GIGE PL + P ++ + + P +P NS + W P+ S ++ Y
Sbjct: 9801 GIGE----PLDSEPETARNL-FSVPGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPVTGYW 9855
Query: 643 LRWRPKNSVGRWK-------EATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRF 695
L + S RWK +A G SY + GL G Y+ ++ +I G +
Sbjct: 9856 LEMKDTTSK-RWKRVNRDPIKAMTLGV--SYKVTGLIEGSDYQFRVYAINAAGVGPASL- 9911
Query: 696 DFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWV----SASDTVSGFR 751
S P T+ P +P VT+ T SS + W V+G+
Sbjct: 9912 ------PSDPATARD------PIAPPGPPFPKVTDWTKSSADLEWSPPLKDGGSKVTGYI 9959
Query: 752 VEYELSEEGDEP--QYLDLPSTATSVNIPDLLPGRKY-----IVNVYQISEDGEQSLILS 804
VEY+ EEG E + D T + + L G Y VN+ I E GE + ++
Sbjct: 9960 VEYK--EEGKEEWEKGKDKEVRGTKLVVTGLKEGAFYKFRVRAVNIAGIGEPGEVTDVIE 10017
Query: 805 TSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETA-- 862
PD +D IVV I P+V + E LP+ A
Sbjct: 10018 MKDRLVS---PDLQLDASVRDRIVVHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEATI 10074
Query: 863 ------NSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFV 916
+S+ + + Q Q ++ A E E +I VP P F+
Sbjct: 10075 ETTAISSSMVIKNCQRSHQGVYSLLAKNEAGERKKTIIVDVLD-------VPGPVGTPFL 10127
Query: 917 --EVTDVKVTIMWTPPE----SAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPG 970
+T+ + W PE S +T Y ++ + ++R A V GL G
Sbjct: 10128 AHNLTNESCKLTWFSPEDDGGSPITNYVIEKRESDRRAWTPVTYTVTRQN-ATVQGLIQG 10186
Query: 971 VTYYFKVFA---VSHG---RESKPLTAQQT-TKLDAPTNLQFVNETDSTVLVRWTPPR-- 1021
Y+F++ A + G S+ L ++ T + P +L+ T +TV + W PP+
Sbjct: 10187 KAYFFRIAAENSIGMGPFVETSEALVIREPITVPERPEDLEVKEVTKNTVTLTWNPPKYD 10246
Query: 1022 --AQITGYRLTVGLTRRGQPRQYNVGPSVS-KYPLRNLQPAS--EYTVSLVAIKG 1071
++I Y L L + + +S KY ++ L+ EY VS V I G
Sbjct: 10247 GGSEIINYVLESRLIGTEKFHKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVG 10301
Score = 52.8 bits (125), Expect = 4e-06
Identities = 80/336 (23%), Positives = 120/336 (35%), Gaps = 46/336 (13%)
Query: 602 LQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQP---SHISKYILRWRPKN-SVGRWKEA 657
++ Y S P + +T+ ++ S + W+AP S I+ Y++ R + W+E
Sbjct: 8995 VEVYDRPSPPRNLAVTDIKAE--SCYLTWDAPLDNGGSEITHYVIDKRDASRKKAEWEEV 9052
Query: 658 TIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTP 717
T Y I L P YE ++ ++ +YG + + D V + P
Sbjct: 9053 TNTAVEKRYGIWKLIPNGQYEFRVRAVNKYGISDECKSD-------KVVIQDPYRLPGPP 9105
Query: 718 FSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTA----- 772
P V T S +VSW D Y L + + Y S A
Sbjct: 9106 GKPKVLAR------TKGSMLVSWTPPLDNGGSPITGYWLEKREEGSPYWSRVSRAPITKV 9159
Query: 773 ----TSVNIPDLLPGRKY-----IVNVYQISEDGEQSLILSTSQTTAPDAPPD-PTVDQV 822
N+P LL G KY +N I E S P PP P V
Sbjct: 9160 GLKGVEFNVPRLLEGVKYQFRAMAINAAGIGPPSEPSDPEVAGDPIFPPGPPSCPEVKDK 9219
Query: 823 DDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPE---TANSVTLSDLQPGVQ 875
+SI + W P +PI GY + +N P+ T + +L+ +
Sbjct: 9220 TKSSISLGWKPPAKDGGSPIKGYIVEMQEEGTTDWKRVNEPDKLITTCECVVPNLKELRK 9279
Query: 876 YNITIYAVEENQESTPVVIQQETTG-TPRSDTVPSP 910
Y + AV E ES P +TTG P +D P
Sbjct: 9280 YRFRVKAVNEAGESEP----SDTTGEIPATDIQEEP 9311
Score = 50.4 bits (119), Expect = 2e-05
Identities = 182/937 (19%), Positives = 327/937 (34%), Gaps = 131/937 (13%)
Query: 1277 DITDSSIGLRWTPLNS---STIIGYRITV-VAAGEGIPIFEDFVDSSVGYYTVTGLEPGI 1332
DIT+++ + WT S S I GY + G+ + + + + + VTGL G
Sbjct: 11217 DITENAATVSWTLPKSDGGSPITGYYMERREVTGKWVRVNKTPIADLK--FRVTGLYEGN 11274
Query: 1333 DYDISVITLINGGESAPTTLTQQTAV-------PPPTDLRFTNIGPDTMRVTWAPPPSID 1385
Y+ V G S P+ + PP + + + +T + W P S D
Sbjct: 11275 TYEFRVFAENLAGLSKPSPSSDPIKACRPIKPPGPPINPKLKDKSRETADLVWTKPLS-D 11333
Query: 1386 LTNFLVRYSPVKNEEDVAELSISPSDN-----AVVLTNLLPGTEYVVSVSSVYEQHESTP 1440
+ ++ Y + A+ + D A + L+ G EY + + E P
Sbjct: 11334 GGSPILGYVVECQKPGTAQWNRINKDELIRQCAFRVPGLIEGNEYRFRIKAANIVGEGEP 11393
Query: 1441 LRGRQKT---GLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRV 1497
+ + P ++ D+T + I R++ PE +E +V
Sbjct: 11394 RELAESVIAKDILHPPEVEL-DVTCRDVITVRVGQTIRILA-RVKGRPEPDITWTKEGKV 11451
Query: 1498 PHSRNSITLTNLTPGTE-------------YVVSIVALNGREESPLLIGQQSTVSDVP-- 1542
+ L P E Y++S +G + ++ V D P
Sbjct: 11452 LVREKRVDLIQDLPRVELQIKEAVRADHGKYIISAKNSSGHAQGSAIVN----VLDRPGP 11507
Query: 1543 -RDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISG--- 1598
++L+V T + ISW+ P + G + + + E+ P K + ++
Sbjct: 11508 CQNLKVTNVTKENCTISWENP--------LDNGGSEITNFIVEYRKPNQKGWSIVASDVT 11559
Query: 1599 -------LKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQ---MQVTDVQDNS 1648
L +Y V A G P I ID+P + + + D
Sbjct: 11560 KRLIKANLLANNEYYFRVCAENKVGVGPTIETKTPILAINPIDRPGEPENLHIADKGKTF 11619
Query: 1649 ISVKW----LPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVY 1704
+ +KW SP Y V K + +T ++ Y V
Sbjct: 11620 VYLKWRRPDYDGGSPNLSYHVERRLKGSDDWERVHKGSIKETHYMVDRCVENQIYEFRVQ 11679
Query: 1705 AQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSI-------KIAWESPQGQVSRYRVTY 1757
+N GES V+T + D+ + + I E+ V +
Sbjct: 11680 TKNEGGESD-WVKTEEVVVKEDLQKPVLDLKLSGVLTVKAGDTIRLEAGVRGKPFPEVAW 11738
Query: 1758 SSPEDGIHELFPAP----DGEEDTAELQGLRP----GSEYTVSVVALHDDMESQPLIGTQ 1809
+ +D +L +P D D+++ + G +Y V+ + +
Sbjct: 11739 TKDKDAT-DLTRSPRVKIDTRADSSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATVNVL 11797
Query: 1810 STAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVV 1869
P +LK V+ + W PP G ++ EK K + + S++V+
Sbjct: 11798 DKPGPV-RNLKIVDVSSDRCTVCWDPPEDD-GGCEIQNYILEKC-ETKRMVWSTYSATVL 11854
Query: 1870 VSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENV---------SPPRRARVTDATETT 1920
G V E + Y + ++ G T + V P VT ++
Sbjct: 11855 TPGTTVTRLIEGNEYIFRVRAENKIGTGPPTESKPVIAKTKYDKPGRPDPPEVTKVSKEE 11914
Query: 1921 ITISWRTKT----ETITGFQVDAVPANGQ--TPIQRTIKPDVRSYTITGLQPGTDYKIYL 1974
+T+ W ++ITG+ ++ + P+ ++ P+ R + L P +Y+ +
Sbjct: 11915 MTVVWNPPEYDGGKSITGYFLEKKEKHSTRWVPVNKSAIPE-RRMKVQNLLPDHEYQFRV 11973
Query: 1975 YTLND------NARSSPVVI-DASTAIDAPSNLRFLATTPNSLLVSWQPP----RARITG 2023
N+ + S PVV D P+N R + TT +S+ + W P A I G
Sbjct: 11974 KAENEIGIGEPSLPSRPVVAKDPIEPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAPIIG 12033
Query: 2024 YIIKYEK--PGSPPREVVPRPRPGV----TEATITGLEPGTEYTIYVIALKNNQKSEPLI 2077
Y+++ + P E R E T+T L+ EY V A NQ +
Sbjct: 12034 YVVEMRPKIADASPDEGWKRCNAAAQLVRKEFTVTSLDENQEYEFRVCA--QNQ-----V 12086
Query: 2078 GRKKTDELPQLVTLPHPNLHGPEILDVPSTVQKTPFV 2114
G + EL + + P L PEI D+ ++++K V
Sbjct: 12087 GIGRPAELKEAIK-PKEILEPPEI-DLDASMRKLVIV 12121
Score = 48.5 bits (114), Expect = 8e-05
Identities = 107/537 (19%), Positives = 187/537 (34%), Gaps = 65/537 (12%)
Query: 610 GPVEVFITETPSQPNSHPIQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSY 666
GPV ++ + H + W P+ S ++ YI+ R + W T S+
Sbjct: 12203 GPVSDLKVSDVTKTSCH-VSWAPPENDGGSQVTHYIVEKREADRK-TWSTVTPEVKKTSF 12260
Query: 667 TIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSE 726
+ L PG Y ++ ++ +YG T PV ++ E P L
Sbjct: 12261 HVTNLVPGNEYYFRVTAVNEYG-------PGVPTDVPKPVLASDPLSEPDPPRKL----- 12308
Query: 727 SVTEITASSFVVSWV----SASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLP 782
VTE+T +S ++W+ + G+ Y E+ + S+ + L
Sbjct: 12309 EVTEMTKNSATLAWLPPLRDGGAKIDGYITSYREEEQPADRWTEYSVVKDLSLVVTGLKE 12368
Query: 783 GRKY-----IVNVYQISEDGEQSLILSTSQTTAPD---APPDPTVDQVDDTSIVVRWSRP 834
G+KY N +S E + + P P T+ I
Sbjct: 12369 GKKYKFRVAARNAVGVSLPREAEGVYEAKEQLLPPKILMPEQITIKAGKKLRIEAHVYGK 12428
Query: 835 QAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDL--QPGVQYNITIYAVEENQESTPV 892
P ++ V S ++ ++++ + + D+ + Y++T
Sbjct: 12429 PHPTCKWKKGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIK 12488
Query: 893 VIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPG 948
V+ + G P+ P D+ ++ ++ W P S +T Y V+ V+ G
Sbjct: 12489 VVVMDAPGPPQ-----PPFDISDIDAD--ACSLSWHIPLEDGGSNITNYIVEKCDVS-RG 12540
Query: 949 EHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKL------DAPTN 1002
+ L T V L PG Y F+V A + S+PLT+ + P N
Sbjct: 12541 DWVTALASVTKTSCRVGKLIPGQEYIFRVRAENRFGISEPLTSPKMVAQFPFGVPSEPKN 12600
Query: 1003 LQFVNETDSTVLVRWTPPRAQ----ITGYRLTVGLTRRGQPRQYNVGPSV---SKYPLRN 1055
+ + V W P + I GY + R ++ ++YP
Sbjct: 12601 ARVTKVNKDCIFVAWDRPDSDGGSPIIGY--LIERKERNSLLWVKANDTLVRSTEYPCAG 12658
Query: 1056 LQPASEYTVSLVAIKGNQESP--KATGVFTTLQPGSSIPPYNTE---VTETTIVITW 1107
L EY+ + A+ SP K T T P PP E VT++T+ + W
Sbjct: 12659 LVEGLEYSFRIYALNKAGSSPPSKPTEYVTARMPVD--PPGKPEVIDVTKSTVSLIW 12713
Score = 47.4 bits (111), Expect = 2e-04
Identities = 68/293 (23%), Positives = 108/293 (36%), Gaps = 33/293 (11%)
Query: 730 EITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQY----LDLPSTATSVNIPDLLPGRK 785
+I S VSW +D + Y L E + P+ +D TS+ + L +
Sbjct: 23742 DIQVRSVRVSWRPPADDGGADILGYIL-ERREVPKAAWYTIDSRVRGTSLVVKGLKENVE 23800
Query: 786 YIVNVYQISEDGEQSLILSTSQTTA-----PDAPPD--PTVDQVDDTSIVVRWSRPQ--- 835
Y V ++ G + S T P PP P V V +S+ + WSRP+
Sbjct: 23801 YHFRVSAENQFGISKPLKSEEPVTPKTPLNPPEPPSNPPEVLDVTKSSVSLSWSRPKDDG 23860
Query: 836 -APITGYRIVYSPSVEGSSTELNLPE-TANSVTLSDLQPGVQYNITIYAV------EENQ 887
+ +TGY I + N + T T++ L P +Y I A E +
Sbjct: 23861 GSRVTGYYIERKETSTDKWVRHNKTQITTTMYTVTGLVPDAEYQFRIIAQNDVGLSETSP 23920
Query: 888 ESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIP 943
S PVV + D P +L+ + ++ VT+ W PE + GY V+
Sbjct: 23921 ASEPVVCKDPF------DKPSQPGELEILSISKDSVTLQWEKPECDGGKEILGYWVEYRQ 23974
Query: 944 VNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTK 996
++ + GL Y F+VFA + S+P + K
Sbjct: 23975 SGDSAWKKSNKERIKDKQFTIGGLLEATEYEFRVFAENETGLSRPRRTAMSIK 24027
Score = 43.9 bits (102), Expect = 0.002
Identities = 50/204 (24%), Positives = 83/204 (40%), Gaps = 22/204 (10%)
Query: 717 PFSPLVATSESVTEITASSFVVSWVSASDT----VSGFRVEYELSEEGDEPQYLDLPSTA 772
P P+V + + +S V+SW +D ++ + VE ++EG E Q + +
Sbjct: 24229 PTGPIV-----IEALLKNSAVISWKPPADDGGSWITNYVVEKCEAKEGAEWQLVSSAISV 24283
Query: 773 TSVNIPDLLPGRKYIV-----NVYQISEDGE-QSLILSTSQTTAPDAPPDPTVDQVDDTS 826
T+ I +L Y N + IS+ E S+++ S P AP PT+ V S
Sbjct: 24284 TTCRIVNLTENAGYYFRVSAQNTFGISDPLEVSSVVIIKSPFEKPGAPGKPTITAVTKDS 24343
Query: 827 IVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSV-TLSDLQPGVQYNITIY 881
VV W P A I Y + + + E +V ++ +L G++Y +
Sbjct: 24344 CVVAWKPPASDGGAKIRNYYLEKREKKQNKWISVTTEEIRETVFSVKNLIEGLEYEFRVK 24403
Query: 882 AVEENQESTPVVIQQETTGTPRSD 905
ES I + TP+SD
Sbjct: 24404 CENLGGESEWSEISEPI--TPKSD 24425
Score = 41.2 bits (95), Expect = 0.013
Identities = 92/413 (22%), Positives = 157/413 (38%), Gaps = 51/413 (12%)
Query: 1376 VTWAPPPSID---LTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSV 1432
++W PP +TN++V K + +S + S + NL Y VS+
Sbjct: 24245 ISWKPPADDGGSWITNYVVEKCEAKEGAEWQLVSSAISVTTCRIVNLTENAGYYFRVSAQ 24304
Query: 1433 YEQHESTPLRGRQKTGLDSPTGID-------FSDITANSFTVHWIAPRATITGYRIRHHP 1485
S PL + SP + +T +S V W P A+ G +IR++
Sbjct: 24305 NTFGISDPLEVSSVVIIKSPFEKPGAPGKPTITAVTKDSCVVAW-KPPASDGGAKIRNYY 24363
Query: 1486 EHFSGRPREDRVPHSRNSITLT-----NLTPGTEYVVSIVA--LNGREESPLLIGQQSTV 1538
+ + + + I T NL G EY + L G E + +
Sbjct: 24364 LEKREKKQNKWISVTTEEIRETVFSVKNLIEGLEYEFRVKCENLGGESEWSEISEPITPK 24423
Query: 1539 SDVP----------RDLEVVAATPTSLLISWDA-PAVTVRYYRITYGET----GGNSPVQ 1583
SDVP R+L V + +L+ P V++YR G+ G +Q
Sbjct: 24424 SDVPIQAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYR--QGKEIIADGLKYRIQ 24481
Query: 1584 EFTVPGSKSTATISGLKPGVDYTITVYAV--TGRGDSPASSKPISINYRTEIDKPSQMQ- 1640
EF G I+ + D TVY V T +G S + + + + +I P ++
Sbjct: 24482 EFK--GGYHQLIIASV---TDDDATVYQVRATNQGGSVSGTASLEVEVPAKIHLPKTLEG 24536
Query: 1641 ---VTDVQDNSISVKWLPSSS---PVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQ 1694
V ++ +S+K +P S PV ++ + G + + + G++
Sbjct: 24537 MGAVHALRGEVVSIK-IPFSGKPDPVITWQKGQDLIDNNGHYQVIVTRSFTSLVFPNGVE 24595
Query: 1695 PTVEYVVSVYAQNPSGESQPLVQTAVTNI-DRPKGLAFTDVDVDSIKIAWESP 1746
V A+N G Q V+ V ++ D P+G+ +DV DS+ + W P
Sbjct: 24596 RKDAGFYVVCAKNRFGIDQKTVELDVADVPDPPRGVKVSDVSRDSVNLTWTEP 24648
Score = 37.7 bits (86), Expect = 0.14
Identities = 36/131 (27%), Positives = 53/131 (40%), Gaps = 8/131 (6%)
Query: 894 IQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPVNLPGE 949
I Q+T +D PR ++ +V+ V + WT P S +T Y V+ E
Sbjct: 24612 IDQKTVELDVADVPDPPRGVKVSDVSRDSVNLTWTEPASDGGSKITNYIVEKCATT--AE 24669
Query: 950 HGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQ--TTKLDAPTNLQFVN 1007
R+ +R T V L +Y F+V A + SKP + TK D + +
Sbjct: 24670 RWLRVGQARETRYTVINLFGKTSYQFRVIAENKFGLSKPSEPSEPTITKEDKTRAMNYDE 24729
Query: 1008 ETDSTVLVRWT 1018
E D T V T
Sbjct: 24730 EVDETREVSMT 24740
Score = 35.0 bits (79), Expect = 0.92
Identities = 38/169 (22%), Positives = 71/169 (42%), Gaps = 17/169 (10%)
Query: 1610 YAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWL-PSS---SPVTGYRV 1665
Y V + K + ++ D P ++V+DV +S+++ W P+S S +T Y V
Sbjct: 24602 YVVCAKNRFGIDQKTVELDVADVPDPPRGVKVSDVSRDSVNLTWTEPASDGGSKITNYIV 24661
Query: 1666 TTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPL--VQTAVTNI 1723
+ A +T T+ L Y V A+N G S+P + +T
Sbjct: 24662 EKCATTAERWLRVGQA--RETRYTVINLFGKTSYQFRVIAENKFGLSKPSEPSEPTITKE 24719
Query: 1724 DRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPD 1772
D+ + + + D +VD + +VS + ++SS ++ + A D
Sbjct: 24720 DKTRAMNY-DEEVDETR--------EVSMTKASHSSTKELYEKYMIAED 24759
>gi|119220552 sidekick 1 [Homo sapiens]
Length = 2213
Score = 166 bits (419), Expect = 3e-40
Identities = 280/1342 (20%), Positives = 500/1342 (37%), Gaps = 195/1342 (14%)
Query: 737 VVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTA---TSVNIPDLLPGRKYIVNVYQI 793
V+SWV D S E + P + L + T V + L P R Y V +
Sbjct: 687 VLSWVRPFDGNSPILYYIVELSENNSPWKVHLSNVGPEMTGVTVSGLTPARTYQFRVCAV 746
Query: 794 SEDGEQSLILSTSQTTAPDAPPDPTVDQV-----DDTSIVVRWSRP---------QAPIT 839
+E G TS+ P+ PP + + SI+V+W P + I
Sbjct: 747 NEVGRGQYSAETSRLMLPEEPPSAPPKNIVASGRTNQSIMVQWQPPPETEHNGVLRGYIL 806
Query: 840 GYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETT 899
YR+ P E + PE N ++DL QY I + A N V + T
Sbjct: 807 RYRLAGLPG-EYQQRNITSPE-VNYCLVTDLIIWTQYEIQVAAY--NGAGLGVFSRAVTE 862
Query: 900 GTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAV-----TGYRVDVIPVNLPGEHGQRL 954
T + P+++Q V + +W PP GY++ P + P E +
Sbjct: 863 YTLQGVPTAPPQNVQTEAVNSTTIQFLWNPPPQQFINGINQGYKLLAWPADAP-EAVTVV 921
Query: 955 PISRN----TFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQ----QTTKLDAPTNLQFV 1006
I+ + +T L Y+ V + + P T Q Q K A +L F
Sbjct: 922 TIAPDFHGVHHGHITNLKKFTAYFTSVLCFTTPGDGPPSTPQLVWTQEDKPGAVGHLSFT 981
Query: 1007 NETDSTVLVRWTPPRAQ---ITGYRLTVGLTRRGQPR-QYNVGPSVSKYPLRNLQPASEY 1062
D+++ V W P + ITGY+++ + R R + + + +Y ++ L + Y
Sbjct: 982 EILDTSLKVSWQEPLEKNGIITGYQISWEVYGRNDSRLTHTLNSTTHEYKIQGLSSLTTY 1041
Query: 1063 TVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPS 1122
T+ + A+ + TG+ T+ S +PP ++ +P L RP
Sbjct: 1042 TIDVAAV-----TAVGTGLVTSSTISSGVPPDLPGAPSNLVISNISPR---SATLQFRPG 1093
Query: 1123 QGGEA------------------------PREVTSDSGSIVVSGLTPGVEYVYTI-QVLR 1157
G+ E D+ + + LTP Y + + QV
Sbjct: 1094 YDGKTSISRWIVEGQVGAIGDEEEWVTLYEEENEPDAQMLEIPNLTPYTHYRFRMKQVNI 1153
Query: 1158 DGQERDAPIVNKVVTPLSP----PTNLHLEANPDTGVLTVSW------ERSTTPDITGYR 1207
G +P + T +P PT++ + +T L + W + + P+ GYR
Sbjct: 1154 VGPSPYSPSSRVIQTLQAPPDVAPTSVTVRTASETS-LRLRWVPLPDSQYNGNPESVGYR 1212
Query: 1208 ITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVK-------------DDK 1254
I ++ Q + V + T + L +EY + + +
Sbjct: 1213 IKYWRSDLQSSAVAQVVSDRLEREFTIEELEEWMEYELQMQAFNAVGAGPWSEVVRGRTR 1272
Query: 1255 ESVPISDTIIPEVPQLTDLSFVDITDSSIGLRWTPL----NSSTIIGYRITVVAAG-EGI 1309
ESVP + PE ++S ++ + I L WT + + I+GY+I A +
Sbjct: 1273 ESVP---SAAPE-----NVSAEAVSSTQILLTWTSVPEQDQNGLILGYKILFRAKDLDPE 1324
Query: 1310 PIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTT-----LTQQTAVPPPTDL 1364
P + + GL + Y++ V+ G P+T T+ A PP L
Sbjct: 1325 PRSHIVRGNHTQSALLAGLRKFVLYELQVLAFTRIGNGVPSTPLILERTKDDAPGPPVRL 1384
Query: 1365 RFTNIGPDTMRVTWAPP--PSIDLTNFLVRYSPVKNE-EDVAELSISPSDNAVVLTNLLP 1421
F + ++R+ W PP P+ + + + Y + + + + T+L P
Sbjct: 1385 VFPEVRLTSVRIVWQPPEEPNGIILGYQIAYRLASSSPHTFTTVEVGATVRQFTATDLAP 1444
Query: 1422 GTEYVVSVSSVYEQHESTPLRG-------RQKTGLDSPTGIDFSDITANSFTVHWIAPRA 1474
+ Y+ +S+ Q PL R++ + +++TA S + W+
Sbjct: 1445 ESAYIFRLSAKTRQGWGEPLEATVITTEKRERPAPPRELLVPQAEVTARSLRLQWVP--G 1502
Query: 1475 TITGYRIRHHPEHFSGRPR------EDRVPHSRNSITLTNLTPGTEYVVSIVALNGREES 1528
+ IR+ PR + H + + L P T Y + + A N +S
Sbjct: 1503 SDGASPIRYFTMQVRELPRGEWQTYSSSISHEATACVVDRLRPFTSYKLRLKATNDIGDS 1562
Query: 1529 PLLIGQQ--STVSDVPRDLE-VVAATP---TSLLISWDAPA-----VTVRYYRITYG--- 1574
+ +T+ DVP + V+ATP +S+LI W P ++ YRI Y
Sbjct: 1563 DFSSETEAVTTLQDVPGEPPGSVSATPHTTSSVLIQWQPPRDESLNGLLQGYRIYYRELE 1622
Query: 1575 -ETGGNSPVQ----------------EFTVPGSKSTAT---ISGLKPGVDYTITVYAVTG 1614
E G + + F S ST+T ++ LK Y + + A
Sbjct: 1623 YEAGSGTEAKTLKNPIALHAELTAQSSFKTVNSSSTSTMCELTHLKKYRRYEVIMTAYNI 1682
Query: 1615 RGDSPASSK-PISINYRTEIDKPSQMQVTDVQDNSISVKWLP-----SSSPVTGYRVTTT 1668
G+SPAS+ + + P +QVT + + + V W P + + GY++
Sbjct: 1683 IGESPASAPVEVFVGEAAPAMAPQNVQVTPLTASQLEVTWDPPPPESQNGNIQGYKIYYW 1742
Query: 1669 PKNGPGPT-KTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE---SQPLV-QTAVTNI 1723
+ T K K + + ++ L +Y+VS+ A N +G+ S P +T
Sbjct: 1743 EADSQNETEKMKVLFLPEPVVRLKNLTSHTKYLVSISAFNAAGDGPKSDPQQGRTHQAAP 1802
Query: 1724 DRPKGLAFTDVDVDSIKIAWESP---QGQVSRYRVTYS--SPEDGIHELFPAP--DGEED 1776
P LAF+++ ++ ++W P G + YRV Y +P G+ ++ +
Sbjct: 1803 GAPSFLAFSEITSTTLNVSWGEPAAANGILQGYRVVYEPLAPVQGVSKVVTVEVRGNWQR 1862
Query: 1777 TAELQGLRPGSEYTVSV----VALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQ 1832
+++ L G Y V + ++++ G + +P D+ T+ + + L+ Q
Sbjct: 1863 WLKVRDLTKGVTYFFRVQARTITYGPELQANITAGPAEGSPGSPRDVLVTK-SASELTLQ 1921
Query: 1833 WT---PPNVQLTGYRVRVTPKEK---TGPMKEINLAPDSSSVVVSGLMVATKYEVSVYAL 1886
WT + TGY + P ++ +K+I + S ++ + L YE V A+
Sbjct: 1922 WTEGHSGDTPTTGYVIEARPSDEGLWDMFVKDIPRSATSYTLSLDKLRQGVTYEFRVVAV 1981
Query: 1887 KDTLTSRPAQGVVTTLENVSPP 1908
+ P+ V P
Sbjct: 1982 NEAGYGEPSNPSTAVSAQVEAP 2003
Score = 137 bits (346), Expect = 1e-31
Identities = 248/1135 (21%), Positives = 431/1135 (37%), Gaps = 162/1135 (14%)
Query: 1043 NVGPSVSKYPLRNLQPASEYTVSLVAIKG---NQESPKATGVFTTLQPGSSIPPYNTEV- 1098
NVGP ++ + L PA Y + A+ Q S + + + +P S+ PP N
Sbjct: 720 NVGPEMTGVTVSGLTPARTYQFRVCAVNEVGRGQYSAETSRLMLPEEPPSA-PPKNIVAS 778
Query: 1099 --TETTIVITWTPAPRI-------GFKLGVRPS--QGGEAPREVTS-DSGSIVVSGLTPG 1146
T +I++ W P P G+ L R + G R +TS + +V+ L
Sbjct: 779 GRTNQSIMVQWQPPPETEHNGVLRGYILRYRLAGLPGEYQQRNITSPEVNYCLVTDLIIW 838
Query: 1147 VEYVYTIQVLRDGQERDAPIVNKVVT-------PLSPPTNLHLEANPDTGVLTVSWERST 1199
+Y + + ++ VT P +PP N+ EA T + + W
Sbjct: 839 TQYEIQVAAYNGA---GLGVFSRAVTEYTLQGVPTAPPQNVQTEAVNSTTIQFL-WNPPP 894
Query: 1200 TPDITG----YRITTTPTNGQQGNSLEEV------VHADQSSCTFDNLSPGLEYNVSVYT 1249
I G Y++ P + + ++ + VH + NL Y SV
Sbjct: 895 QQFINGINQGYKLLAWPADAPEAVTVVTIAPDFHGVHHGHIT----NLKKFTAYFTSVLC 950
Query: 1250 VKDDKESVPISDTII----PEVPQLTDLSFVDITDSSIGLRWT-PLNSSTII-GYRITVV 1303
+ P + ++ + + LSF +I D+S+ + W PL + II GY+I+
Sbjct: 951 FTTPGDGPPSTPQLVWTQEDKPGAVGHLSFTEILDTSLKVSWQEPLEKNGIITGYQISWE 1010
Query: 1304 AAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAVPP--- 1360
G ++S+ Y + GL Y I V + G T+ T + VPP
Sbjct: 1011 VYGRNDSRLTHTLNSTTHEYKIQGLSSLTTYTIDVAAVTAVGTGLVTSSTISSGVPPDLP 1070
Query: 1361 --PTDLRFTNIGPDTMRVTWAP--PPSIDLTNFLV--RYSPVKNEED---VAELSISPSD 1411
P++L +NI P + + + P ++ ++V + + +EE+ + E P
Sbjct: 1071 GAPSNLVISNISPRSATLQFRPGYDGKTSISRWIVEGQVGAIGDEEEWVTLYEEENEPDA 1130
Query: 1412 NAVVLTNLLPGTEYVVSVSSVY------EQHESTPLRGRQKTGLDSPTGIDFSDITANSF 1465
+ + NL P T Y + V S ++ Q +PT + + S
Sbjct: 1131 QMLEIPNLTPYTHYRFRMKQVNIVGPSPYSPSSRVIQTLQAPPDVAPTSVTVRTASETSL 1190
Query: 1466 TVHWIA-------PRATITGYRIRHHPEHFSGRPREDRVPHS-RNSITLTNLTPGTEYVV 1517
+ W+ GYRI++ V T+ L EY +
Sbjct: 1191 RLRWVPLPDSQYNGNPESVGYRIKYWRSDLQSSAVAQVVSDRLEREFTIEELEEWMEYEL 1250
Query: 1518 SIVALNGREESP---LLIGQ--QSTVSDVPRDLEVVAATPTSLLISWDAPAVT-----VR 1567
+ A N P ++ G+ +S S P ++ A + T +L++W + +
Sbjct: 1251 QMQAFNAVGAGPWSEVVRGRTRESVPSAAPENVSAEAVSSTQILLTWTSVPEQDQNGLIL 1310
Query: 1568 YYRITYGETGGNSPVQEFTVPGSKS-TATISGLKPGVDYTITVYAVTGRGDSPASSKPIS 1626
Y+I + + + V G+ + +A ++GL+ V Y + V A T G+ S+ P+
Sbjct: 1311 GYKILFRAKDLDPEPRSHIVRGNHTQSALLAGLRKFVLYELQVLAFTRIGNGVPST-PLI 1369
Query: 1627 INYRTEIDKPS---QMQVTDVQDNSISVKWLPSSSP---VTGYRVT-TTPKNGPGPTKTK 1679
+ RT+ D P ++ +V+ S+ + W P P + GY++ + P T
Sbjct: 1370 LE-RTKDDAPGPPVRLVFPEVRLTSVRIVWQPPEEPNGIILGYQIAYRLASSSPHTFTTV 1428
Query: 1680 TAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDR-----PKGLAFTDV 1734
G + T L P Y+ + A+ G +PL T +T R P+ L
Sbjct: 1429 EVGATVRQFTATDLAPESAYIFRLSAKTRQGWGEPLEATVITTEKRERPAPPRELLVPQA 1488
Query: 1735 DVD--SIKIAWESPQGQVSRYRVTYSSPED---GIHELFPAPDGEEDTA-ELQGLRPGSE 1788
+V S+++ W S R + G + + + E TA + LRP +
Sbjct: 1489 EVTARSLRLQWVPGSDGASPIRYFTMQVRELPRGEWQTYSSSISHEATACVVDRLRPFTS 1548
Query: 1789 YTVSVVALHD----DMESQPLIGTQSTAIPA--PTDLKFTQVTPTSLSAQWTPP-----N 1837
Y + + A +D D S+ T +P P + T T +S+ QW PP N
Sbjct: 1549 YKLRLKATNDIGDSDFSSETEAVTTLQDVPGEPPGSVSATPHTTSSVLIQWQPPRDESLN 1608
Query: 1838 VQLTGYRVRVTPKE---------KT--------------GPMKEINLAPDSSSVVVSGLM 1874
L GYR+ E KT K +N + S+ ++ L
Sbjct: 1609 GLLQGYRIYYRELEYEAGSGTEAKTLKNPIALHAELTAQSSFKTVNSSSTSTMCELTHLK 1668
Query: 1875 VATKYEVSVYA---LKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISW-----R 1926
+YEV + A + ++ S P + V P+ +VT T + + ++W
Sbjct: 1669 KYRRYEVIMTAYNIIGESPASAPVEVFVGEAAPAMAPQNVQVTPLTASQLEVTWDPPPPE 1728
Query: 1927 TKTETITGFQVDAVPANGQTPIQRTI-----KPDVRSYTITGLQPGTDYKIYLYTLN--- 1978
++ I G+++ A+ Q ++ +P VR +T T Y + + N
Sbjct: 1729 SQNGNIQGYKIYYWEADSQNETEKMKVLFLPEPVVRLKNLTS---HTKYLVSISAFNAAG 1785
Query: 1979 DNARSSPVVIDASTAID-APSNLRFLATTPNSLLVSWQPPRAR---ITGYIIKYE 2029
D +S P A APS L F T +L VSW P A + GY + YE
Sbjct: 1786 DGPKSDPQQGRTHQAAPGAPSFLAFSEITSTTLNVSWGEPAAANGILQGYRVVYE 1840
Score = 125 bits (315), Expect = 4e-28
Identities = 240/1096 (21%), Positives = 396/1096 (36%), Gaps = 141/1096 (12%)
Query: 1056 LQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEV----TETTIVITWTPAP 1111
+Q A YT +G S A+ T S + P V T T+ T P
Sbjct: 545 IQDAGNYTCYAANTEG---SLNASATLTVWNRTSIVHPPEDHVVIKGTTATLHCGATHDP 601
Query: 1112 RIGFKLGVRPSQGGEAP----REVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIV 1167
R+ + + P R V GS+++S G Y+ +++ +G
Sbjct: 602 RVSLRYVWKKDNVALTPSSTSRIVVEKDGSLLISQTWSGDIGDYSCEIVSEGGNDSRMAR 661
Query: 1168 NKVVTPLSPPTNLHLEANPD-TGVLTVSWER---STTPDITGYRITTTPTNGQQGNSLEE 1223
+V+ P NL + N + + +SW R +P + Y I N
Sbjct: 662 LEVIELPHSPQNLLVSPNSSHSHAVVLSWVRPFDGNSPIL--YYIVELSENNSPWKVHLS 719
Query: 1224 VVHADQSSCTFDNLSPGLEYNVSVYTVKD---DKESVPISDTIIPEVPQLT---DLSFVD 1277
V + + T L+P Y V V + + S S ++PE P ++
Sbjct: 720 NVGPEMTGVTVSGLTPARTYQFRVCAVNEVGRGQYSAETSRLMLPEEPPSAPPKNIVASG 779
Query: 1278 ITDSSIGLRWTPL----NSSTIIGYRITVVAAG-EGIPIFEDFVDSSVGYYTVTGLEPGI 1332
T+ SI ++W P ++ + GY + AG G + V Y VT L
Sbjct: 780 RTNQSIMVQWQPPPETEHNGVLRGYILRYRLAGLPGEYQQRNITSPEVNYCLVTDLIIWT 839
Query: 1333 DYDISVITLINGG----ESAPTTLTQQTAVP--PPTDLRFTNIGPDTMRVTWAPPPSIDL 1386
Y+I V G A T T Q VP PP +++ + T++ W PPP +
Sbjct: 840 QYEIQVAAYNGAGLGVFSRAVTEYTLQ-GVPTAPPQNVQTEAVNSTTIQFLWNPPPQQFI 898
Query: 1387 TNFLVRYS----PVKNEEDVAELSISPSDNAVV---LTNLLPGTEYVVSVSSVYEQHEST 1439
Y P E V ++I+P + V +TNL T Y SV +
Sbjct: 899 NGINQGYKLLAWPADAPEAVTVVTIAPDFHGVHHGHITNLKKFTAYFTSVLCFTTPGDGP 958
Query: 1440 PLRGRQK-TGLDSPTGI---DFSDITANSFTVHWIAP---RATITGYRIRHHPEHFSGRP 1492
P + T D P + F++I S V W P ITGY+I GR
Sbjct: 959 PSTPQLVWTQEDKPGAVGHLSFTEILDTSLKVSWQEPLEKNGIITGYQISWE---VYGR- 1014
Query: 1493 REDRVPHSRNSIT----LTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVV 1548
+ R+ H+ NS T + L+ T Y + + A+ L+ + S VP DL
Sbjct: 1015 NDSRLTHTLNSTTHEYKIQGLSSLTTYTIDVAAVTAVGTG--LVTSSTISSGVPPDLP-- 1070
Query: 1549 AATPTSLLISWDAPAVTVRYYRITY------------GETGGNSPVQEFTVPGSKSTAT- 1595
P++L+IS +P +R Y G+ G +E+ +
Sbjct: 1071 -GAPSNLVISNISPRSATLQFRPGYDGKTSISRWIVEGQVGAIGDEEEWVTLYEEENEPD 1129
Query: 1596 -----ISGLKPGVDYTITVYAVTGRGDSP--ASSKPISINYRTEIDKPSQMQVTDVQDNS 1648
I L P Y + V G SP SS+ I P+ + V + S
Sbjct: 1130 AQMLEIPNLTPYTHYRFRMKQVNIVGPSPYSPSSRVIQTLQAPPDVAPTSVTVRTASETS 1189
Query: 1649 ISVKWLP-------SSSPVTGYRVTTTPKNGPGPTKTKTAGPD-QTEMTIEGLQPTVEYV 1700
+ ++W+P + GYR+ + + + E TIE L+ +EY
Sbjct: 1190 LRLRWVPLPDSQYNGNPESVGYRIKYWRSDLQSSAVAQVVSDRLEREFTIEELEEWMEYE 1249
Query: 1701 VSVYAQNP----------SGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQV 1750
+ + A N G ++ V +A + ++ T + + + + G +
Sbjct: 1250 LQMQAFNAVGAGPWSEVVRGRTRESVPSAAPENVSAEAVSSTQILLTWTSVPEQDQNGLI 1309
Query: 1751 SRYRVTYSSPEDGIHELFPAP------DGEEDTAELQGLRPGSEYTVSVVA---LHDDME 1801
Y++ + + + L P P +A L GLR Y + V+A + + +
Sbjct: 1310 LGYKILFRAKD-----LDPEPRSHIVRGNHTQSALLAGLRKFVLYELQVLAFTRIGNGVP 1364
Query: 1802 SQPLI--GTQSTAIPAPTDLKFTQVTPTSLSAQWTPP---NVQLTGYRVRVT-PKEKTGP 1855
S PLI T+ A P L F +V TS+ W PP N + GY++
Sbjct: 1365 STPLILERTKDDAPGPPVRLVFPEVRLTSVRIVWQPPEEPNGIILGYQIAYRLASSSPHT 1424
Query: 1856 MKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLEN---VSPPRRAR 1912
+ + + L + Y + A P + V T E +PPR
Sbjct: 1425 FTTVEVGATVRQFTATDLAPESAYIFRLSAKTRQGWGEPLEATVITTEKRERPAPPRELL 1484
Query: 1913 VTDA--TETTITISWRTKTETITGF-----QVDAVPANGQTPIQRTIKPDVRSYTITGLQ 1965
V A T ++ + W ++ + QV +P +I + + + L+
Sbjct: 1485 VPQAEVTARSLRLQWVPGSDGASPIRYFTMQVRELPRGEWQTYSSSISHEATACVVDRLR 1544
Query: 1966 PGTDYKIYLYTLND------NARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPR- 2018
P T YK+ L ND ++ + V + P ++ T +S+L+ WQPPR
Sbjct: 1545 PFTSYKLRLKATNDIGDSDFSSETEAVTTLQDVPGEPPGSVSATPHTTSSVLIQWQPPRD 1604
Query: 2019 ----ARITGYIIKYEK 2030
+ GY I Y +
Sbjct: 1605 ESLNGLLQGYRIYYRE 1620
Score = 108 bits (269), Expect = 9e-23
Identities = 229/1087 (21%), Positives = 408/1087 (37%), Gaps = 163/1087 (14%)
Query: 1138 IVVSGLTPGVEYVYTIQVLRD-GQERDAPIVNKVVTPLSPPT----NLHLEANPDTGVLT 1192
+ VSGLTP Y + + + + G+ + + ++++ P PP+ N+ + ++
Sbjct: 728 VTVSGLTPARTYQFRVCAVNEVGRGQYSAETSRLMLPEEPPSAPPKNIVASGRTNQSIM- 786
Query: 1193 VSWERSTTPDITG--------YRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYN 1244
V W+ + G YR+ P QQ N + + + C +L +Y
Sbjct: 787 VQWQPPPETEHNGVLRGYILRYRLAGLPGEYQQRN----ITSPEVNYCLVTDLIIWTQYE 842
Query: 1245 VSVYTVKDDKESV---PISDTIIPEVPQLT--DLSFVDITDSSIGLRWTPLNSSTIIG-- 1297
+ V V +++ + VP ++ + ++I W P I G
Sbjct: 843 IQVAAYNGAGLGVFSRAVTEYTLQGVPTAPPQNVQTEAVNSTTIQFLWNPPPQQFINGIN 902
Query: 1298 --YRITVVAAGEG-----IPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPT 1350
Y++ A + I DF G+ +T L+ Y SV+ G+ P+
Sbjct: 903 QGYKLLAWPADAPEAVTVVTIAPDFHGVHHGH--ITNLKKFTAYFTSVLCFTTPGDGPPS 960
Query: 1351 T----LTQQTAVPPPTDLRFTNIGPDTMRVTWAPPPSID--LTNFLVRYSPVKNEEDVAE 1404
T TQ+ L FT I +++V+W P + +T + + + +
Sbjct: 961 TPQLVWTQEDKPGAVGHLSFTEILDTSLKVSWQEPLEKNGIITGYQISWEVYGRNDSRLT 1020
Query: 1405 LSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLD-----SPTGIDFSD 1459
+++ + + + L T Y + V++V +G+ +P+ + S+
Sbjct: 1021 HTLNSTTHEYKIQGLSSLTTYTIDVAAVTAVGTGLVTSSTISSGVPPDLPGAPSNLVISN 1080
Query: 1460 ITANSFTVHW---IAPRATITGYRIRHH------PEHFSGRPREDRVPHSRNSITLTNLT 1510
I+ S T+ + + +I+ + + E + E+ P ++ + + NLT
Sbjct: 1081 ISPRSATLQFRPGYDGKTSISRWIVEGQVGAIGDEEEWVTLYEEENEPDAQ-MLEIPNLT 1139
Query: 1511 PGTEY-----VVSIVALNGREESPLLIGQQSTVSDV-PRDLEVVAATPTSLLISWDAPAV 1564
P T Y V+IV + S +I DV P + V A+ TSL + W P
Sbjct: 1140 PYTHYRFRMKQVNIVGPSPYSPSSRVIQTLQAPPDVAPTSVTVRTASETSLRLRW-VPLP 1198
Query: 1565 TVRY--------YRITYGETG-GNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGR 1615
+Y YRI Y + +S V + + TI L+ ++Y + + A
Sbjct: 1199 DSQYNGNPESVGYRIKYWRSDLQSSAVAQVVSDRLEREFTIEELEEWMEYELQMQAFNAV 1258
Query: 1616 GDSPASSKPISINYRTEIDKPS----QMQVTDVQDNSISVKWLP-----SSSPVTGYRVT 1666
G P S + RT PS + V I + W + + GY++
Sbjct: 1259 GAGPWSEV---VRGRTRESVPSAAPENVSAEAVSSTQILLTWTSVPEQDQNGLILGYKIL 1315
Query: 1667 TTPKN-GPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQP-----LVQTAV 1720
K+ P P G + GL+ V Y + V A G P L +T
Sbjct: 1316 FRAKDLDPEPRSHIVRGNHTQSALLAGLRKFVLYELQVLAFTRIGNGVPSTPLILERTKD 1375
Query: 1721 TNIDRPKGLAFTDVDVDSIKIAW---ESPQGQVSRYRVTYSSPEDGIHELFPAPDG---E 1774
P L F +V + S++I W E P G + Y++ Y H G
Sbjct: 1376 DAPGPPVRLVFPEVRLTSVRIVWQPPEEPNGIILGYQIAYRLASSSPHTFTTVEVGATVR 1435
Query: 1775 EDTAELQGLRPGSEYTVSVVALHDDMESQPL----IGTQSTAIPAPTD---LKFTQVTPT 1827
+ TA L P S Y + A +PL I T+ PAP + +VT
Sbjct: 1436 QFTAT--DLAPESAYIFRLSAKTRQGWGEPLEATVITTEKRERPAPPRELLVPQAEVTAR 1493
Query: 1828 SLSAQWTPPN-----VQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVS 1882
SL QW P + ++ +VR P+ + +++ ++++ VV L T Y++
Sbjct: 1494 SLRLQWVPGSDGASPIRYFTMQVRELPRGEWQTYSS-SISHEATACVVDRLRPFTSYKLR 1552
Query: 1883 VYALKDTLTS--RPAQGVVTTLENV--SPPRRARVTDATETTITISWRTKTET-----IT 1933
+ A D S VTTL++V PP T T +++ I W+ + +
Sbjct: 1553 LKATNDIGDSDFSSETEAVTTLQDVPGEPPGSVSATPHTTSSVLIQWQPPRDESLNGLLQ 1612
Query: 1934 GFQV-------------------DAVPANGQTPIQRTIKPDVRSYT-----ITGLQPGTD 1969
G+++ + + + + Q + K S T +T L+
Sbjct: 1613 GYRIYYRELEYEAGSGTEAKTLKNPIALHAELTAQSSFKTVNSSSTSTMCELTHLKKYRR 1672
Query: 1970 YKIYLYTLN---DNARSSPVVIDASTAIDA--PSNLRFLATTPNSLLVSWQPP-----RA 2019
Y++ + N ++ S+PV + A A P N++ T + L V+W PP
Sbjct: 1673 YEVIMTAYNIIGESPASAPVEVFVGEAAPAMAPQNVQVTPLTASQLEVTWDPPPPESQNG 1732
Query: 2020 RITGYIIKYEKPGS----PPREVVPRPRPGVTEATITGLEPGTEYTIYVIALK---NNQK 2072
I GY I Y + S +V+ P P V + L T+Y + + A + K
Sbjct: 1733 NIQGYKIYYWEADSQNETEKMKVLFLPEPVV---RLKNLTSHTKYLVSISAFNAAGDGPK 1789
Query: 2073 SEPLIGR 2079
S+P GR
Sbjct: 1790 SDPQQGR 1796
Score = 77.0 bits (188), Expect = 2e-13
Identities = 103/475 (21%), Positives = 184/475 (38%), Gaps = 52/475 (10%)
Query: 1604 DYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISV--KWL---PSSS 1658
DY+ + + G A + I + + P + V+ +S +V W+ +S
Sbjct: 644 DYSCEIVSEGGNDSRMARLEVIELPH-----SPQNLLVSPNSSHSHAVVLSWVRPFDGNS 698
Query: 1659 PVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQT 1718
P+ Y V + N P GP+ T +T+ GL P Y V A N G Q +T
Sbjct: 699 PILYYIVELSENNSPWKVHLSNVGPEMTGVTVSGLTPARTYQFRVCAVNEVGRGQYSAET 758
Query: 1719 AVTNIDR------PKGLAFTDVDVDSIKIAWESP---------QGQVSRYRVTYSSPEDG 1763
+ + PK + + SI + W+ P +G + RYR+ P +
Sbjct: 759 SRLMLPEEPPSAPPKNIVASGRTNQSIMVQWQPPPETEHNGVLRGYILRYRLA-GLPGEY 817
Query: 1764 IHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHD---DMESQPLIGTQSTAIPA--PTD 1818
+P E + + L ++Y + V A + + S+ + +P P +
Sbjct: 818 QQRNITSP--EVNYCLVTDLIIWTQYEIQVAAYNGAGLGVFSRAVTEYTLQGVPTAPPQN 875
Query: 1819 LKFTQVTPTSLSAQWTPPNVQL-----TGYRVRVTPKEKTGPMKEINLAPDSSSV---VV 1870
++ V T++ W PP Q GY++ P + + + +APD V +
Sbjct: 876 VQTEAVNSTTIQFLWNPPPQQFINGINQGYKLLAWPADAPEAVTVVTIAPDFHGVHHGHI 935
Query: 1871 SGLMVATKYEVSVYALKDTLTSRPA--QGVVTTLENVSPPRRARVTDATETTITISWR-- 1926
+ L T Y SV P+ Q V T + T+ +T++ +SW+
Sbjct: 936 TNLKKFTAYFTSVLCFTTPGDGPPSTPQLVWTQEDKPGAVGHLSFTEILDTSLKVSWQEP 995
Query: 1927 -TKTETITGFQVD-AVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSS 1984
K ITG+Q+ V + + T+ Y I GL T Y I + + A +
Sbjct: 996 LEKNGIITGYQISWEVYGRNDSRLTHTLNSTTHEYKIQGLSSLTTYTIDVAAV--TAVGT 1053
Query: 1985 PVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVV 2039
+V ++ + P + L P++L++S PR+ + Y+ S R +V
Sbjct: 1054 GLVTSSTISSGVPPD---LPGAPSNLVISNISPRSATLQFRPGYDGKTSISRWIV 1105
Score = 74.3 bits (181), Expect = 1e-12
Identities = 143/675 (21%), Positives = 244/675 (36%), Gaps = 109/675 (16%)
Query: 662 HLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPL 721
H S + GL+ V+YE Q+++ + G+ STP+ T + P P+
Sbjct: 1334 HTQSALLAGLRKFVLYELQVLAFTRIGN----------GVPSTPLILER-TKDDAPGPPV 1382
Query: 722 VATSESVTEITASSFVVSWVSASD---TVSGFRVEYELSEEGDEP-QYLDLPSTATSVNI 777
E+ +S + W + + G+++ Y L+ +++ +T
Sbjct: 1383 RLV---FPEVRLTSVRIVWQPPEEPNGIILGYQIAYRLASSSPHTFTTVEVGATVRQFTA 1439
Query: 778 PDLLPGRKYIVNVYQISEDG----EQSLILSTSQTTAPDAPPDPTVDQVDDT--SIVVRW 831
DL P YI + + G ++ +++T + P P + V Q + T S+ ++W
Sbjct: 1440 TDLAPESAYIFRLSAKTRQGWGEPLEATVITTEKRERPAPPRELLVPQAEVTARSLRLQW 1499
Query: 832 ---SRPQAPITGY--RIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEE- 885
S +PI + ++ P E + ++ A + + L+P Y + + A +
Sbjct: 1500 VPGSDGASPIRYFTMQVRELPRGEWQTYSSSISHEATACVVDRLRPFTSYKLRLKATNDI 1559
Query: 886 -----NQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP-----ESAVT 935
+ E+ V Q+ G P +P T V I W PP +
Sbjct: 1560 GDSDFSSETEAVTTLQDVPGEPPGSVSATPH-------TTSSVLIQWQPPRDESLNGLLQ 1612
Query: 936 GYRVDVIPVNLPGEHGQ-----RLPI------------------SRNTFAEVTGLSPGVT 972
GYR+ + G + PI S +T E+T L
Sbjct: 1613 GYRIYYRELEYEAGSGTEAKTLKNPIALHAELTAQSSFKTVNSSSTSTMCELTHLKKYRR 1672
Query: 973 Y-----YFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP-----RA 1022
Y + + S + + AP N+Q T S + V W PP
Sbjct: 1673 YEVIMTAYNIIGESPASAPVEVFVGEAAPAMAPQNVQVTPLTASQLEVTWDPPPPESQNG 1732
Query: 1023 QITGYRLTV-GLTRRGQPRQYNV----GPSVSKYPLRNLQPASEYTVSLVAIKGNQESPK 1077
I GY++ + + + V P V L+NL ++Y VS+ A + PK
Sbjct: 1733 NIQGYKIYYWEADSQNETEKMKVLFLPEPVVR---LKNLTSHTKYLVSISAFNAAGDGPK 1789
Query: 1078 A---TGVFTTLQPGSSIPPYNTEVTETTIVITW-TPAPRIGFKLGVRPSQGGEAPREVTS 1133
+ G PG+ +E+T TT+ ++W PA G G R AP + S
Sbjct: 1790 SDPQQGRTHQAAPGAPSFLAFSEITSTTLNVSWGEPAAANGILQGYRVVYEPLAPVQGVS 1849
Query: 1134 DSGSIVVSG----------LTPGVEYVYTIQ--VLRDGQERDAPIVNKVVTPLSPPTNLH 1181
++ V G LT GV Y + +Q + G E A I SP +
Sbjct: 1850 KVVTVEVRGNWQRWLKVRDLTKGVTYFFRVQARTITYGPELQANITAGPAEG-SPGSPRD 1908
Query: 1182 LEANPDTGVLTVSWERSTTPD--ITGYRITTTPTNGQQGNSLEEVVHADQSSCT--FDNL 1237
+ LT+ W + D TGY I P++ + + + +S T D L
Sbjct: 1909 VLVTKSASELTLQWTEGHSGDTPTTGYVIEARPSDEGLWDMFVKDIPRSATSYTLSLDKL 1968
Query: 1238 SPGLEYNVSVYTVKD 1252
G+ Y V V +
Sbjct: 1969 RQGVTYEFRVVAVNE 1983
Score = 73.6 bits (179), Expect = 2e-12
Identities = 105/399 (26%), Positives = 153/399 (38%), Gaps = 51/399 (12%)
Query: 1780 LQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPA------PTDLKFTQVTPTSLSAQW 1833
+ GL P Y V A+++ Q T +P P ++ + T S+ QW
Sbjct: 730 VSGLTPARTYQFRVCAVNEVGRGQYSAETSRLMLPEEPPSAPPKNIVASGRTNQSIMVQW 789
Query: 1834 TPP-----NVQLTGYRVRVTPKEKTGPMKEINL-APDSSSVVVSGLMVATKYEVSVYALK 1887
PP N L GY +R G ++ N+ +P+ + +V+ L++ T+YE+ V A
Sbjct: 790 QPPPETEHNGVLRGYILRYRLAGLPGEYQQRNITSPEVNYCLVTDLIIWTQYEIQVAAYN 849
Query: 1888 DT--------LTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETIT-----G 1934
+T QGV T +PP+ + TTI W + G
Sbjct: 850 GAGLGVFSRAVTEYTLQGVPT-----APPQNVQTEAVNSTTIQFLWNPPPQQFINGINQG 904
Query: 1935 FQVDAVPANGQTPIQR-TIKPD---VRSYTITGLQPGTDY---KIYLYTLNDNARSSPVV 1987
+++ A PA+ + TI PD V IT L+ T Y + T D S+P +
Sbjct: 905 YKLLAWPADAPEAVTVVTIAPDFHGVHHGHITNLKKFTAYFTSVLCFTTPGDGPPSTPQL 964
Query: 1988 IDASTAIDAPS---NLRFLATTPNSLLVSWQPPRAR---ITGYIIKYEKPGSPPREVVPR 2041
+ T D P +L F SL VSWQ P + ITGY I +E G +
Sbjct: 965 V--WTQEDKPGAVGHLSFTEILDTSLKVSWQEPLEKNGIITGYQISWEVYGRNDSRLTHT 1022
Query: 2042 PRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELPQLVTLPHPNLHGPEI 2101
E I GL T YTI V A+ + P L P NL I
Sbjct: 1023 LNSTTHEYKIQGLSSLTTYTIDVAAVTAVGTGLVTSSTISSGVPPDLPGAP-SNLVISNI 1081
Query: 2102 LDVPSTVQKTPFVTHPGYDTGNGIQLPGTSGQQPSVGQQ 2140
+T+Q PGYD I GQ ++G +
Sbjct: 1082 SPRSATLQ-----FRPGYDGKTSISRWIVEGQVGAIGDE 1115
Score = 33.5 bits (75), Expect = 2.7
Identities = 23/82 (28%), Positives = 40/82 (48%), Gaps = 8/82 (9%)
Query: 1994 IDAPSNLRFLATTPNS-----LLVSWQPP---RARITGYIIKYEKPGSPPREVVPRPRPG 2045
I+ P + + L +PNS +++SW P + I YI++ + SP + + P
Sbjct: 665 IELPHSPQNLLVSPNSSHSHAVVLSWVRPFDGNSPILYYIVELSENNSPWKVHLSNVGPE 724
Query: 2046 VTEATITGLEPGTEYTIYVIAL 2067
+T T++GL P Y V A+
Sbjct: 725 MTGVTVSGLTPARTYQFRVCAV 746
>gi|222352127 sidekick 2 [Homo sapiens]
Length = 2172
Score = 165 bits (418), Expect = 5e-40
Identities = 269/1145 (23%), Positives = 439/1145 (38%), Gaps = 173/1145 (15%)
Query: 1043 NVGPSVSKYPLRNLQPASEYTVSLVAIK--GNQESPKATGVFTTLQPGSSIPPYNTEV-- 1098
+V P + ++ L PA Y L A+ G + K T + + + PP N
Sbjct: 642 SVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSLPEEPPTAPPQNVIASG 701
Query: 1099 -TETTIVITWTPAPR-----------IGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPG 1146
T +I+I W P P I + L P G + +D ++++ L
Sbjct: 702 RTNQSIMIQWQPPPESHQNGILKGYIIRYCLAGLPV-GYQFKNITDADVNNLLLEDLIIW 760
Query: 1147 VEYVYTIQVLRDGQERDAPIVNKVV------TPLSPPTNLHLEANPDT------------ 1188
Y I+V +KV P PP N+H EA T
Sbjct: 761 TNY--EIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNVHAEATNSTTIRFTWNAPSPQ 818
Query: 1189 -------GVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGL 1241
G ++WE ++T +T P + ++ +H S L
Sbjct: 819 FINGINQGYKLIAWEPEQEEEVT--MVTARP-------NFQDSIHVGFVS----GLKKFT 865
Query: 1242 EYNVSVY---TVKDDKESVPISDTIIPEVP-QLTDLSFVDITDSSIGLRWTPLNSST--I 1295
EY SV T D S P +VP + LSF +I D+S+ + W +
Sbjct: 866 EYFTSVLCFTTPGDGPRSTPQLVRTHEDVPGPVGHLSFSEILDTSLKVSWQEPGEKNGIL 925
Query: 1296 IGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQ 1355
GYRI+ ++ + Y VTGL Y I V + + G+ + T
Sbjct: 926 TGYRISWEEYNRTNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQVSASTIS 985
Query: 1356 TAVPP-----PTDLRFTNIGPDTMRVTWAP--PPSIDLTNFLV--RYSPVKNEED---VA 1403
+ VPP PT+L +NIGP ++ + + P ++ +LV + V E+ +
Sbjct: 986 SGVPPELPGPPTNLGISNIGPRSVTLQFRPGYDGKTSISRWLVEAQVGVVGEGEEWLLIH 1045
Query: 1404 ELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGL------DSPTGIDF 1457
+LS P ++ + +L P T Y + V S P + +K +P +
Sbjct: 1046 QLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQPSRKIQTLQAPPDMAPANVSL 1105
Query: 1458 SDITANSFTVHWIA-------PRATITGYRIRHHPEHFSGRPR----EDRVPHSRNSITL 1506
+ S + W+ GY+I++ G+ +DRV T+
Sbjct: 1106 RTASETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDRV---ERDYTI 1162
Query: 1507 TNLTPGTEYVVSIVALNGREESP---LLIGQ--QSTVSDVPRDLEVVAATPTSLLISW-D 1560
+L TEY V + A N P ++G+ +S S P ++ +A T +S+L+ W +
Sbjct: 1163 EDLEEWTEYRVQVQAFNAIGSGPWSQTVVGRTRESVPSSGPTNVSALATTSSSMLVRWSE 1222
Query: 1561 APAVT----VRYYRITYGETGGNSPVQEFTVPGSKS-TATISGLKPGVDYTITVYAVTGR 1615
P V Y++ Y E ++ + + V G+ S +A ++GL V Y + V A T
Sbjct: 1223 VPEADRNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSRSAQLTGLGKYVLYEVQVLAFTRI 1282
Query: 1616 GDSPASSKPISINYRTEIDKPSQ-MQVTDVQDNSISVKWLPSSSP---VTGYRVTTTPKN 1671
GD S PI ++ P + +V+ S+ + W P ++P + Y++T
Sbjct: 1283 GDGSPSHPPILERTLDDVPGPPMGILFPEVRTTSVRLIWQPPAAPNGIILAYQITHRLNT 1342
Query: 1672 GPGPTKT-KTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNI--DRPKG 1728
T T + P + T GL+P Y+ + AQ G + VT DRP+
Sbjct: 1343 TTANTATVEVLAPSARQYTATGLKPESVYLFRITAQTRKGWGEAAEALVVTTEKRDRPQP 1402
Query: 1729 -----LAFTDVDVDSIKIAWESPQGQVSR---YRVTYSSPEDGIHELFPAPDGEEDTAEL 1780
+ DV S+ ++WE +S Y + G L A ++ +
Sbjct: 1403 PSRPMVQQEDVRARSVLLSWEPGSDGLSPVRYYTIQTRELPSGRWALHSASVSHNASSFI 1462
Query: 1781 -QGLRPGSEYTVSVVALHD------DMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQW 1833
L+P + Y V A +D ES+ L Q+ APT L T T TS+ +W
Sbjct: 1463 VDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTILSVTPHTTTSVLIRW 1522
Query: 1834 TPP-----NVQLTGYRVR---------------------VTPKEKTGPMKEINLA-PDSS 1866
PP N L G+R+R T E T NL+ P +
Sbjct: 1523 QPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGINNPGATWAELTSMYSMRNLSRPSLT 1582
Query: 1867 SVVVSGLMVATKYEV--SVY-ALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITI 1923
+ L +YE+ SVY A+ + +S P + V + PR V AT T + +
Sbjct: 1583 QYELDNLNKHRRYEIRMSVYNAVGEGPSSPPQEVFVGEAVPTAAPRNVVVHGATATQLDV 1642
Query: 1924 SWR-----TKTETITGFQVDAVPANGQTPIQR--TIKPDVRSYTITGLQPGTDYKIYLYT 1976
+W ++ I G+++ A +R T+ S + L T Y + +
Sbjct: 1643 TWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLFLAENSVKLKNLTGYTAYMVSVAA 1702
Query: 1977 LN---DNARSSPVVIDASTAI-DAPSNLRFLATTPNSLLVSWQPPR---ARITGYIIKYE 2029
N D RS+P A APS+++F T S+ VSW+ P+ + GY + YE
Sbjct: 1703 FNAAGDGPRSTPTQGQTQQAAPSAPSSVKFSELTTTSVNVSWEAPQFPNGILEGYRLVYE 1762
Query: 2030 KPGSP 2034
P SP
Sbjct: 1763 -PCSP 1766
Score = 144 bits (362), Expect = 1e-33
Identities = 300/1357 (22%), Positives = 493/1357 (36%), Gaps = 181/1357 (13%)
Query: 793 ISEDGEQSLILSTSQTTAPDAPPDP--TVDQVDDTSIVVRWSRP---QAPITGYRIVYSP 847
IS G S P AP P T+ V+ +I + W++P +P+ Y + S
Sbjct: 572 ISAGGNDSRSAHLRVRQLPHAPEHPVATLSTVERRAINLTWTKPFDGNSPLIRYILEMSE 631
Query: 848 SVEGSSTEL-NLPETANSVTLSDLQPGVQYNITIYAVEE------NQESTPVVIQQETTG 900
+ + L ++ A SVT+ L P Y + AV + ++++ V + +E
Sbjct: 632 NNAPWTVLLASVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSLPEEPPT 691
Query: 901 TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESA-----VTGYRVDVIPVNLP-GEHGQRL 954
P + + S R T+ + I W PP + + GY + LP G + +
Sbjct: 692 APPQNVIASGR-------TNQSIMIQWQPPPESHQNGILKGYIIRYCLAGLPVGYQFKNI 744
Query: 955 PISRNTFAEVTGLSPGVTYYFKVFAVSH---GRESKPLT--AQQTTKLDAPTNLQFVNET 1009
+ + L Y +V A + G S +T Q P N+
Sbjct: 745 TDADVNNLLLEDLIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNVHAEATN 804
Query: 1010 DSTVLVRWTPPRAQIT-----GYRLTVGLTRRGQPRQYNVGPSVSKYP----------LR 1054
+T+ W P Q GY+L +P Q V+ P +
Sbjct: 805 STTIRFTWNAPSPQFINGINQGYKLIAW-----EPEQEEEVTMVTARPNFQDSIHVGFVS 859
Query: 1055 NLQPASEYTVSLVAIKGNQESPKATGVFTTLQ---PGSSIPPYNTEVTETTIVITWT-PA 1110
L+ +EY S++ + P++T PG +E+ +T++ ++W P
Sbjct: 860 GLKKFTEYFTSVLCFTTPGDGPRSTPQLVRTHEDVPGPVGHLSFSEILDTSLKVSWQEPG 919
Query: 1111 PRIGFKLGVRPS--QGGEAPREVTSDSGSIV----VSGLTPGVEYVYTIQVLRD---GQE 1161
+ G G R S + VT ++ V+GLT Y + + GQ
Sbjct: 920 EKNGILTGYRISWEEYNRTNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQV 979
Query: 1162 RDAPIVNKVVTPL-SPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNS 1220
+ I + V L PPTNL + +N +T+ + + R G G
Sbjct: 980 SASTISSGVPPELPGPPTNLGI-SNIGPRSVTLQFRPGYDGKTSISRWLVEAQVGVVGEG 1038
Query: 1221 LEEVV------HADQSSCTFDNLSPGLEYNVSVYTVKDDKESVP------ISDTIIPEVP 1268
E ++ D S +L+P Y+ + V S P I P
Sbjct: 1039 EEWLLIHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQPSRKIQTLQAPPDM 1098
Query: 1269 QLTDLSFVDITDSSIGLRWTPL------NSSTIIGYRITVVAA-GEGIPIFEDFVDSSVG 1321
++S +++S+ LRW PL + +GY+I + G G + D
Sbjct: 1099 APANVSLRTASETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDRVER 1158
Query: 1322 YYTVTGLEPGIDYDISV--ITLINGGESAPTTLTQQTAVPP---PTDLRFTNIGPDTMRV 1376
YT+ LE +Y + V I G + T + + P PT++ +M V
Sbjct: 1159 DYTIEDLEEWTEYRVQVQAFNAIGSGPWSQTVVGRTRESVPSSGPTNVSALATTSSSMLV 1218
Query: 1377 TWAPPPSIDLTNFLVRYSPVKNEEDVAE-----LSISPSDNAVVLTNLLPGTEYVVSVSS 1431
W+ P D ++ Y + E+D L S + LT L Y V V +
Sbjct: 1219 RWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSRSAQLTGLGKYVLYEVQVLA 1278
Query: 1432 VYEQHESTPLRGR--QKTGLD---SPTGIDFSDITANSFTVHW---IAPRATITGYRIRH 1483
+ +P ++T D P GI F ++ S + W AP I Y+I H
Sbjct: 1279 FTRIGDGSPSHPPILERTLDDVPGPPMGILFPEVRTTSVRLIWQPPAAPNGIILAYQITH 1338
Query: 1484 HPEHFSGRPREDRV-PHSRNSITLTNLTPGTEYVVSIVALN----GREESPLLIGQQSTV 1538
+ V S T T L P + Y+ I A G L++ +
Sbjct: 1339 RLNTTTANTATVEVLAPSARQYTATGLKPESVYLFRITAQTRKGWGEAAEALVVTTEKRD 1398
Query: 1539 SDVPRDLEVVAATPT---SLLISWDAPA---VTVRYYRITYGET-GGNSPVQEFTVPGSK 1591
P +V S+L+SW+ + VRYY I E G + +V +
Sbjct: 1399 RPQPPSRPMVQQEDVRARSVLLSWEPGSDGLSPVRYYTIQTRELPSGRWALHSASVSHNA 1458
Query: 1592 STATISGLKPGVDYTITVYAVTGRGDSPASSKPISIN--YRTEIDKPSQMQVTDVQDNSI 1649
S+ + LKP Y V A GDS S + S+ + P+ + VT S+
Sbjct: 1459 SSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTILSVTPHTTTSV 1518
Query: 1650 SVKWLPSSSP-----VTGYRV-------------TTTPKNGPGPTKTKTAG--------- 1682
++W P + + G+R+ T N PG T +
Sbjct: 1519 LIRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGINNPGATWAELTSMYSMRNLSR 1578
Query: 1683 PDQTEMTIEGLQPTVEYVV--SVY---AQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVD 1737
P T+ ++ L Y + SVY + PS Q + P+ +
Sbjct: 1579 PSLTQYELDNLNKHRRYEIRMSVYNAVGEGPSSPPQEVFVGEAVPTAAPRNVVVHGATAT 1638
Query: 1738 SIKIAWESP-----QGQVSRYRVTYSSPEDG-----IHELFPAPDGEEDTAELQGLRPGS 1787
+ + WE P G + Y++ + + G + LF A E++ +L+ L +
Sbjct: 1639 QLDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLFLA----ENSVKLKNLTGYT 1694
Query: 1788 EYTVSVVALH---DDMESQPLIG-TQSTAIPAPTDLKFTQVTPTSLSAQWTP---PNVQL 1840
Y VSV A + D S P G TQ A AP+ +KF+++T TS++ W PN L
Sbjct: 1695 AYMVSVAAFNAAGDGPRSTPTQGQTQQAAPSAPSSVKFSELTTTSVNVSWEAPQFPNGIL 1754
Query: 1841 TGYRVRVTP-KEKTGPMKEINLAPDSSS---VVVSGLMVATKYEVSVYALKDTLTSRPAQ 1896
GYR+ P G K + + +S + V L Y + A T
Sbjct: 1755 EGYRLVYEPCSPVDGVSKIVTVDVKGNSPLWLKVKDLAEGVTYRFRIRAKTFTYGPEIEA 1814
Query: 1897 GVVTTLENVSP-PRRARVTDATETTITISWRTKTE---TITGFQVDAVPAN-GQTPIQ-R 1950
V T +P P + + I I W + IT + ++A P++ G I +
Sbjct: 1815 NVTTGPGEGAPGPPGVPIIVRYSSAIAIHWSSGDPGKGPITRYVIEARPSDEGLWDILIK 1874
Query: 1951 TIKPDVRSYTITG--LQPGTDYKIYLYTLNDNARSSP 1985
I +V SYT + L+PG Y + +ND +P
Sbjct: 1875 DIPKEVSSYTFSMDILKPGVSYDFRVIAVNDYGFGTP 1911
Score = 140 bits (354), Expect = 1e-32
Identities = 292/1388 (21%), Positives = 523/1388 (37%), Gaps = 197/1388 (14%)
Query: 594 IGEWHCQPLQTYPSSSGPVEVFITETPSQPNSHPIQ-------------WNAPQP--SHI 638
IG + C+ + + S + + + P P HP+ W P S +
Sbjct: 564 IGTYTCRVISAGGNDSRSAHLRVRQLPHAPE-HPVATLSTVERRAINLTWTKPFDGNSPL 622
Query: 639 SKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFT 698
+YIL N+ A++ S T+KGL P Y+ +L ++ G + F
Sbjct: 623 IRYILEMSENNAPWTVLLASVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQ---FSKD 679
Query: 699 TTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDT-----VSGFRVE 753
T S P T P ++A+ T S ++ W ++ + G+ +
Sbjct: 680 TERVSLPEEP-----PTAPPQNVIASGR-----TNQSIMIQWQPPPESHQNGILKGYIIR 729
Query: 754 YELSEEGDEPQYLDL-PSTATSVNIPDLLPGRKYIVNVYQISEDG---EQSLILSTSQTT 809
Y L+ Q+ ++ + ++ + DL+ Y + V + G S + +
Sbjct: 730 YCLAGLPVGYQFKNITDADVNNLLLEDLIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQG 789
Query: 810 APDAPP-DPTVDQVDDTSIVVRWSRPQAPI-----TGYRIV-YSPSVEGSSTEL----NL 858
P PP + + + T+I W+ P GY+++ + P E T + N
Sbjct: 790 VPTVPPGNVHAEATNSTTIRFTWNAPSPQFINGINQGYKLIAWEPEQEEEVTMVTARPNF 849
Query: 859 PETANSVTLSDLQPGVQYNITIYAVE---ENQESTPVVIQQETTGTPRSDTVPSP-RDLQ 914
++ + +S L+ +Y ++ + STP +++ + VP P L
Sbjct: 850 QDSIHVGFVSGLKKFTEYFTSVLCFTTPGDGPRSTPQLVRTH-------EDVPGPVGHLS 902
Query: 915 FVEVTDVKVTIMWTPP---ESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGV 971
F E+ D + + W P +TGYR+ N + VTGL+
Sbjct: 903 FSEILDTSLKVSWQEPGEKNGILTGYRISWEEYNRTNTRVTHYLPNVTLEYRVTGLTALT 962
Query: 972 TYYFKVFAVSHGRESKPLTAQQTTKL-----DAPTNLQFVNETDSTVLVRWTP---PRAQ 1023
TY +V A++ + + + ++ + PTNL N +V +++ P +
Sbjct: 963 TYTIEVAAMTSKGQGQVSASTISSGVPPELPGPPTNLGISNIGPRSVTLQFRPGYDGKTS 1022
Query: 1024 ITGY--RLTVGLTRRGQP----RQYNVGPSVSKYPLRNLQPASEYTVSL--VAIKGNQES 1075
I+ + VG+ G+ Q + P + +L P + Y+ + V I G
Sbjct: 1023 ISRWLVEAQVGVVGEGEEWLLIHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVGTSPP 1082
Query: 1076 PKATGVFTTLQPGSSIPPYNTEV---TETTIVITWTPAPR---------IGFKLGVRPSQ 1123
+ + TLQ + P N + +ET++ + W P P +G+K+ S
Sbjct: 1083 SQPSRKIQTLQAPPDMAPANVSLRTASETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSD 1142
Query: 1124 G-GEAPREVTSD--SGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVV------TPL 1174
G G+ V D + L E Y +QV P VV P
Sbjct: 1143 GHGKTLSHVVQDRVERDYTIEDLEEWTE--YRVQVQAFNAIGSGPWSQTVVGRTRESVPS 1200
Query: 1175 SPPTNLHLEANPDTGVLTVSWERSTTPD----ITGYRITTTPTNGQQGNSLEEVVHADQS 1230
S PTN+ A + +L V W D + GY++ + V
Sbjct: 1201 SGPTNVSALATTSSSML-VRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSR 1259
Query: 1231 SCTFDNLSPGLEYNVSVYT---VKDDKES-VPISDTIIPEVP-QLTDLSFVDITDSSIGL 1285
S L + Y V V + D S PI + + +VP + F ++ +S+ L
Sbjct: 1260 SAQLTGLGKYVLYEVQVLAFTRIGDGSPSHPPILERTLDDVPGPPMGILFPEVRTTSVRL 1319
Query: 1286 RWTP--LNSSTIIGYRIT-VVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDY--DISVIT 1340
W P + I+ Y+IT + + + S YT TGL+P Y I+ T
Sbjct: 1320 IWQPPAAPNGIILAYQITHRLNTTTANTATVEVLAPSARQYTATGLKPESVYLFRITAQT 1379
Query: 1341 LINGGESAP----TTLTQQTAVPPPTDL-RFTNIGPDTMRVTWAPPPSIDLTNFLVRYSP 1395
GE+A TT + PP + + ++ ++ ++W P S L+ VRY
Sbjct: 1380 RKGWGEAAEALVVTTEKRDRPQPPSRPMVQQEDVRARSVLLSW-EPGSDGLSP--VRYYT 1436
Query: 1396 VKNEE------DVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYE------QHESTPLRG 1443
++ E + S+S + ++ ++ L P T Y V + + ES L
Sbjct: 1437 IQTRELPSGRWALHSASVSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTT 1496
Query: 1444 RQKTGLDSPTGIDFSDITANSFTVHWIAP-----RATITGYRIRHHPEHFSG----RPRE 1494
Q ++PT + + T S + W P + G+RIR+ + G R
Sbjct: 1497 LQAAPDEAPTILSVTPHTTTSVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRG 1556
Query: 1495 DRVPH---------------SRNSIT---LTNLTPGTEYVVSIVALNGREESPLLIGQQS 1536
P SR S+T L NL Y + + N E P Q+
Sbjct: 1557 INNPGATWAELTSMYSMRNLSRPSLTQYELDNLNKHRRYEIRMSVYNAVGEGPSSPPQEV 1616
Query: 1537 TVSD-----VPRDLEVVAATPTSLLISWDAPAV-----TVRYYRITYGET-GGNSPVQEF 1585
V + PR++ V AT T L ++W+ P + ++ Y+I + E GN +
Sbjct: 1617 FVGEAVPTAAPRNVVVHGATATQLDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVK 1676
Query: 1586 TVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQ 1645
T+ ++++ + L Y ++V A GD P S+ + PS ++ +++
Sbjct: 1677 TLFLAENSVKLKNLTGYTAYMVSVAAFNAAGDGPRSTPTQGQTQQAAPSAPSSVKFSELT 1736
Query: 1646 DNSISVKWLPSSSP---VTGYRVTTTPKNG-PGPTKTKTA---GPDQTEMTIEGLQPTVE 1698
S++V W P + GYR+ P + G +K T G + ++ L V
Sbjct: 1737 TTSVNVSWEAPQFPNGILEGYRLVYEPCSPVDGVSKIVTVDVKGNSPLWLKVKDLAEGVT 1796
Query: 1699 YVVSVYAQNPSGESQPLVQTAVT-----NIDRPKGLAFTDVDVDSIKIAWES---PQGQV 1750
Y + A+ + P ++ VT P G+ +I I W S +G +
Sbjct: 1797 YRFRIRAK--TFTYGPEIEANVTTGPGEGAPGPPGVPIIVRYSSAIAIHWSSGDPGKGPI 1854
Query: 1751 SRYRVTYSSPEDGIHELFPAPDGEE---DTAELQGLRPGSEYTVSVVALHDDMESQPLIG 1807
+RY + ++G+ ++ +E T + L+PG Y V+A++D P
Sbjct: 1855 TRYVIEARPSDEGLWDILIKDIPKEVSSYTFSMDILKPGVSYDFRVIAVNDYGFGTP--S 1912
Query: 1808 TQSTAIPA 1815
+ S ++PA
Sbjct: 1913 SPSQSVPA 1920
Score = 74.7 bits (182), Expect = 1e-12
Identities = 112/450 (24%), Positives = 173/450 (38%), Gaps = 59/450 (13%)
Query: 1734 VDVDSIKIAWESP---QGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYT 1790
V+ +I + W P + RY + S L + D + + ++GL P Y
Sbjct: 603 VERRAINLTWTKPFDGNSPLIRYILEMSENNAPWTVLLASVDPKATSVTVKGLVPARSYQ 662
Query: 1791 VSVVALHDDMESQPLIGTQSTAIPA------PTDLKFTQVTPTSLSAQWTPP-----NVQ 1839
+ A++D + Q T+ ++P P ++ + T S+ QW PP N
Sbjct: 663 FRLCAVNDVGKGQFSKDTERVSLPEEPPTAPPQNVIASGRTNQSIMIQWQPPPESHQNGI 722
Query: 1840 LTGYRVRVTPKEKTGPMKEINLAP-DSSSVVVSGLMVATKYEVSVYALKDT--------L 1890
L GY +R + N+ D +++++ L++ T YE+ V A +
Sbjct: 723 LKGYIIRYCLAGLPVGYQFKNITDADVNNLLLEDLIIWTNYEIEVAAYNSAGLGVYSSKV 782
Query: 1891 TSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETIT-----GFQVDA-VPANG 1944
T QGV T PP TTI +W + G+++ A P
Sbjct: 783 TEWTLQGVPTV-----PPGNVHAEATNSTTIRFTWNAPSPQFINGINQGYKLIAWEPEQE 837
Query: 1945 QTPIQRTIKPDVRSYT----ITGLQPGTDY---KIYLYTLNDNARSSPVVIDASTAIDAP 1997
+ T +P+ + ++GL+ T+Y + T D RS+P ++ + P
Sbjct: 838 EEVTMVTARPNFQDSIHVGFVSGLKKFTEYFTSVLCFTTPGDGPRSTPQLVRTHEDVPGP 897
Query: 1998 -SNLRFLATTPNSLLVSWQPPRAR---ITGYIIKYEKPGSPPREVVPRPRPGVT-EATIT 2052
+L F SL VSWQ P + +TGY I +E+ V P VT E +T
Sbjct: 898 VGHLSFSEILDTSLKVSWQEPGEKNGILTGYRISWEEYNRTNTRVT-HYLPNVTLEYRVT 956
Query: 2053 GLEPGTEYTIYVIALKN---NQKSEPLIGRKKTDELPQLVTLPHPNLHGPEILDVPSTVQ 2109
GL T YTI V A+ + Q S I ELP P NL I T+Q
Sbjct: 957 GLTALTTYTIEVAAMTSKGQGQVSASTISSGVPPELPG----PPTNLGISNIGPRSVTLQ 1012
Query: 2110 KTPFVTHPGYDTGNGIQLPGTSGQQPSVGQ 2139
PGYD I Q VG+
Sbjct: 1013 -----FRPGYDGKTSISRWLVEAQVGVVGE 1037
Score = 70.9 bits (172), Expect = 2e-11
Identities = 111/557 (19%), Positives = 213/557 (38%), Gaps = 47/557 (8%)
Query: 1504 ITLTNLTPGTEYVVSIVALNGREESP--LLIGQQSTVSDVPRDLEVVAATPTSLL--ISW 1559
I+ T+++ Y G +E+ L++ ++ ++ P+D V+ T S++ ++
Sbjct: 462 ISPTHISDAGTYTCLATNSRGVDEASADLVVWARTRITKPPQDQSVIKGTQASMVCGVTH 521
Query: 1560 DAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSP 1619
D P VT+RY G T G + + S IS G T T ++ G+
Sbjct: 522 D-PRVTIRYIWEKDGATLGTESHPRIRLDRNGSLH-ISQTWSGDIGTYTCRVISAGGNDS 579
Query: 1620 ASSKPISINYRTEIDKPSQMQVTDVQDNSISVKW---LPSSSPVTGYRVTTTPKNGPGPT 1676
S+ + + + ++ V+ +I++ W +SP+ Y + + N P
Sbjct: 580 RSAH-LRVRQLPHAPEHPVATLSTVERRAINLTWTKPFDGNSPLIRYILEMSENNAPWTV 638
Query: 1677 KTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDR------PKGLA 1730
+ P T +T++GL P Y + A N G+ Q T ++ P+ +
Sbjct: 639 LLASVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSLPEEPPTAPPQNVI 698
Query: 1731 FTDVDVDSIKIAWESP-----QGQVSRYRVTYSSPEDGI-HELFPAPDGEEDTAELQGLR 1784
+ SI I W+ P G + Y + Y + ++ D + + L+ L
Sbjct: 699 ASGRTNQSIMIQWQPPPESHQNGILKGYIIRYCLAGLPVGYQFKNITDADVNNLLLEDLI 758
Query: 1785 PGSEYTVSVVALHD---DMESQPLIGTQSTAIPA--PTDLKFTQVTPTSLSAQWTPPNVQ 1839
+ Y + V A + + S + +P P ++ T++ W P+ Q
Sbjct: 759 IWTNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNVHAEATNSTTIRFTWNAPSPQ 818
Query: 1840 L-----TGYRVRVTPKEKTGPMKEINLAPDSSSVV----VSGLMVATKYEVSVYALKDTL 1890
GY++ E+ + + P+ + VSGL T+Y SV
Sbjct: 819 FINGINQGYKLIAWEPEQEEEVTMVTARPNFQDSIHVGFVSGLKKFTEYFTSVLCFTTPG 878
Query: 1891 TS-RPAQGVVTTLENV-SPPRRARVTDATETTITISWR---TKTETITGFQVDAVPANGQ 1945
R +V T E+V P ++ +T++ +SW+ K +TG+++ N
Sbjct: 879 DGPRSTPQLVRTHEDVPGPVGHLSFSEILDTSLKVSWQEPGEKNGILTGYRISWEEYNRT 938
Query: 1946 TPIQRTIKPDVR-SYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAI-----DAPSN 1999
P+V Y +TGL T Y I + + + S+ + P+N
Sbjct: 939 NTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQVSASTISSGVPPELPGPPTN 998
Query: 2000 LRFLATTPNSLLVSWQP 2016
L P S+ + ++P
Sbjct: 999 LGISNIGPRSVTLQFRP 1015
>gi|109633039 protein tyrosine phosphatase, receptor type, F isoform 2
precursor [Homo sapiens]
Length = 1898
Score = 153 bits (387), Expect = 2e-36
Identities = 172/631 (27%), Positives = 264/631 (41%), Gaps = 71/631 (11%)
Query: 1493 REDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPR---DLEVVA 1549
+ED +P RN + L+N+ Y ++ G E+ Q TV +P+ DL V
Sbjct: 274 KEDEMPVGRNVLELSNVVRSANYTCVAISSLGMIEATA----QVTVKALPKPPIDLVVTE 329
Query: 1550 ATPTSLLISWDAP-AVTVRYYRITYGETGGNSPVQEFTVPGSKSTA-TISGLKPGVDYTI 1607
T TS+ ++WD+ + V YY I Y G P QE V G +T +I GL P +Y
Sbjct: 330 TTATSVTLTWDSGNSEPVTYYGIQYRAAGTEGPFQE--VDGVATTRYSIGGLSPFSEYAF 387
Query: 1608 TVYAVTGRGDSPASSKPISINYRTEIDKPS----QMQVTDVQDNSISVKWLPSSSP---V 1660
V AV G P S ++ RT PS ++Q + +++ V+W P P V
Sbjct: 388 RVLAVNSIGRGPPSE---AVRARTGEQAPSSPPRRVQARMLSASTMLVQWEPPEEPNGLV 444
Query: 1661 TGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEG-LQPTVEYVVSVYAQNPSGESQPLVQTA 1719
GYRV TP + P D +T G L P + Y + V A G+ P
Sbjct: 445 RGYRVYYTPDSRRPPNAWHKHNTDAGLLTTVGSLLPGITYSLRVLAFTAVGDGPPSPTIQ 504
Query: 1720 V-TNIDRPKGLAFTDVDVDS---IKIAWE-SPQGQVSRYRVTY--SSPEDGIHELFPAPD 1772
V T P A +V+S I+++W PQ ++ Y + Y + ED H++ P
Sbjct: 505 VKTQQGVPAQPADFQAEVESDTRIQLSWLLPPQERIIMYELVYWAAEDEDQQHKVTFDPT 564
Query: 1773 GEEDTAELQGLRPGSEYTVSVVALHD--------DMESQPLIGTQSTAIPAPTDLKFTQV 1824
+ L+ L+P + Y + A D +E++ QST P + +
Sbjct: 565 S---SYTLEDLKPDTLYRFQLAARSDMGVGVFTPTIEART---AQSTPSAPPQKVMCVSM 618
Query: 1825 TPTSLSAQWTPP-----NVQLTGYRV--RVTPKEKTGPMKEINLAPDSSSVVVSGLMVAT 1877
T++ W PP N +T Y V E G ++ + SS + GL T
Sbjct: 619 GSTTVRVSWVPPPADSRNGVITQYSVAYEAVDGEDRGRHVVDGISREHSSWDLVGLEKWT 678
Query: 1878 KYEVSVYALKDTLTSRPAQGV-VTTLENV--SPPRRARVTDATETTITISWRTKTET--- 1931
+Y V V A D + V V T E+V PPR+ V T + + W+ +
Sbjct: 679 EYRVWVRAHTDVGPGPESSPVLVRTDEDVPSGPPRKVEVEPLNSTAVHVYWKLPVPSKQH 738
Query: 1932 --ITGFQVDAVPANGQTP-----IQRTIKPDVRSYTITGLQPGTDYKIYLY---TLNDNA 1981
I G+QV V P IQ + + + TI+GL P T Y + + T D A
Sbjct: 739 GQIRGYQVTYVRLENGEPRGLPIIQDVMLAEAQETTISGLTPETTYSVTVAAYTTKGDGA 798
Query: 1982 RSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPR---ARITGYIIKYEKPGSPPREV 2038
RS P ++ + A+ + T N+ L+ W PP+ + GY ++Y +
Sbjct: 799 RSKPKIVTTTGAVPGRPTMMISTTAMNTALLQWHPPKELPGELLGYRLQYCRADEARPNT 858
Query: 2039 VPRPRPGVTEATITGLEPGTEYTIYVIALKN 2069
+ + T+TGL GT Y I+ +A KN
Sbjct: 859 IDFGKDD-QHFTVTGLHKGTTY-IFRLAAKN 887
Score = 142 bits (358), Expect = 4e-33
Identities = 167/728 (22%), Positives = 287/728 (39%), Gaps = 68/728 (9%)
Query: 1348 APTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSI 1407
A +T + PP DL T ++ +TW S +T + ++Y E E+
Sbjct: 309 ATAQVTVKALPKPPIDLVVTETTATSVTLTWDSGNSEPVTYYGIQYRAAGTEGPFQEVD- 367
Query: 1408 SPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRG-RQKTGLDSPTG----IDFSDITA 1462
+ + L P +EY V +V P R +TG +P+ + ++A
Sbjct: 368 GVATTRYSIGGLSPFSEYAFRVLAVNSIGRGPPSEAVRARTGEQAPSSPPRRVQARMLSA 427
Query: 1463 NSFTVHWIAPR---ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLT---NLTPGTEYV 1516
++ V W P + GYR+ + P+ S RP H+ ++ LT +L PG Y
Sbjct: 428 STMLVQWEPPEEPNGLVRGYRVYYTPD--SRRPPNAWHKHNTDAGLLTTVGSLLPGITYS 485
Query: 1517 VSIVALNGREESP----LLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVT-VRYYRI 1571
+ ++A + P + + Q V P D + + T + +SW P + Y +
Sbjct: 486 LRVLAFTAVGDGPPSPTIQVKTQQGVPAQPADFQAEVESDTRIQLSWLLPPQERIIMYEL 545
Query: 1572 TYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRT 1631
Y + T + S+ T+ LKP Y + + R D +I RT
Sbjct: 546 VYWAAEDEDQQHKVTFDPT-SSYTLEDLKPDTLYR---FQLAARSDMGVGVFTPTIEART 601
Query: 1632 EIDKPS----QMQVTDVQDNSISVKWLPSSSP-----VTGYRVTTTPKNGPGPTKTKTAG 1682
PS ++ + ++ V W+P + +T Y V +G + G
Sbjct: 602 AQSTPSAPPQKVMCVSMGSTTVRVSWVPPPADSRNGVITQYSVAYEAVDGEDRGRHVVDG 661
Query: 1683 --PDQTEMTIEGLQPTVEYVVSVYAQN---PSGESQPLVQTAVTNIDR--PKGLAFTDVD 1735
+ + + GL+ EY V V A P ES P++ ++ P+ + ++
Sbjct: 662 ISREHSSWDLVGLEKWTEYRVWVRAHTDVGPGPESSPVLVRTDEDVPSGPPRKVEVEPLN 721
Query: 1736 VDSIKIAWESP-----QGQVSRYRVTYSSPEDGIHELFPAPD----GEEDTAELQGLRPG 1786
++ + W+ P GQ+ Y+VTY E+G P E + GL P
Sbjct: 722 STAVHVYWKLPVPSKQHGQIRGYQVTYVRLENGEPRGLPIIQDVMLAEAQETTISGLTPE 781
Query: 1787 SEYTVSVVALH---DDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNV---QL 1840
+ Y+V+V A D S+P I T + A+P + + + QW PP +L
Sbjct: 782 TTYSVTVAAYTTKGDGARSKPKIVTTTGAVPGRPTMMISTTAMNTALLQWHPPKELPGEL 841
Query: 1841 TGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVT 1900
GYR++ ++ P I+ D V+GL T Y + A + +
Sbjct: 842 LGYRLQYCRADEARP-NTIDFGKDDQHFTVTGLHKGTTYIFRLAAKNRAGLGEEFEKEIR 900
Query: 1901 TLENVSP--PRRARVTDATETTITISW-----RTKTETITGFQVDAVPANGQTPIQRTIK 1953
T E++ P+ VT T +T ++W + I + V N Q +Q I
Sbjct: 901 TPEDLPSGFPQNLHVTGLTTSTTELAWDPPVLAERNGRIISYTVVFRDINSQQELQN-IT 959
Query: 1954 PDVRSYTITGLQPGTDY--KIYLYTLNDNARSSPVVIDASTAIDA--PSNLRFLATTPNS 2009
D R +T+TGL+P T Y K+ +T + SP + + ++ N R A S
Sbjct: 960 TDTR-FTLTGLKPDTTYDIKVRAWTSKGSGPLSPSIQSRTMPVEQVFAKNFRVAAAMKTS 1018
Query: 2010 LLVSWQPP 2017
+L+SW+ P
Sbjct: 1019 VLLSWEVP 1026
Score = 130 bits (328), Expect = 1e-29
Identities = 177/732 (24%), Positives = 297/732 (40%), Gaps = 84/732 (11%)
Query: 1399 EEDVAELSISPSDNAVVLTNLLPGTEYV-VSVSSV--YEQHESTPLRGRQKTGLDSPTGI 1455
EE E + N + L+N++ Y V++SS+ E ++ K +D +
Sbjct: 270 EELTKEDEMPVGRNVLELSNVVRSANYTCVAISSLGMIEATAQVTVKALPKPPID----L 325
Query: 1456 DFSDITANSFTVHWIAPRAT-ITGYRIRHHPEHFSGRPRE-DRVPHSRNSITLTNLTPGT 1513
++ TA S T+ W + + +T Y I++ G +E D V +R SI L+P +
Sbjct: 326 VVTETTATSVTLTWDSGNSEPVTYYGIQYRAAGTEGPFQEVDGVATTRYSIG--GLSPFS 383
Query: 1514 EYVVSIVALNGREESP------LLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVT-- 1565
EY ++A+N P G+Q+ S PR ++ + +++L+ W+ P
Sbjct: 384 EYAFRVLAVNSIGRGPPSEAVRARTGEQAP-SSPPRRVQARMLSASTMLVQWEPPEEPNG 442
Query: 1566 -VRYYRITYGETGGNSPV---QEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPAS 1621
VR YR+ Y P + T G +T + L PG+ Y++ V A T GD P S
Sbjct: 443 LVRGYRVYYTPDSRRPPNAWHKHNTDAGLLTT--VGSLLPGITYSLRVLAFTAVGDGPPS 500
Query: 1622 SKPISINYRTEIDKPSQ---MQVTDVQDNSISVKWL-PSSSPVTGYRVTTTPKNGPGPTK 1677
+I +T+ P+Q Q D I + WL P + Y +
Sbjct: 501 P---TIQVKTQQGVPAQPADFQAEVESDTRIQLSWLLPPQERIIMYELVYWAAEDEDQQH 557
Query: 1678 TKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGES--QPLVQTAV---TNIDRPKGLAFT 1732
T P + T+E L+P Y + A++ G P ++ T P+ +
Sbjct: 558 KVTFDPTSS-YTLEDLKPDTLYRFQLAARSDMGVGVFTPTIEARTAQSTPSAPPQKVMCV 616
Query: 1733 DVDVDSIKIAWESP-----QGQVSRYRVTYSSP--EDGIHELFPAPDGEEDTAELQGLRP 1785
+ +++++W P G +++Y V Y + ED + E + +L GL
Sbjct: 617 SMGSTTVRVSWVPPPADSRNGVITQYSVAYEAVDGEDRGRHVVDGISREHSSWDLVGLEK 676
Query: 1786 GSEYTVSVVALHDDM----ESQPLIGTQSTAIPA--PTDLKFTQVTPTSLSAQWTPP--- 1836
+EY V V A H D+ ES P++ +P+ P ++ + T++ W P
Sbjct: 677 WTEYRVWVRA-HTDVGPGPESSPVLVRTDEDVPSGPPRKVEVEPLNSTAVHVYWKLPVPS 735
Query: 1837 --NVQLTGYRVRVTPKEKTGP-----MKEINLAPDSSSVVVSGLMVATKYEVSVYALK-- 1887
+ Q+ GY+V E P ++++ LA ++ +SGL T Y V+V A
Sbjct: 736 KQHGQIRGYQVTYVRLENGEPRGLPIIQDVMLA-EAQETTISGLTPETTYSVTVAAYTTK 794
Query: 1888 -DTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTET---ITGFQVDAVPAN 1943
D S+P +VTT V ++ T + W E + G+++ A+
Sbjct: 795 GDGARSKPK--IVTTTGAVPGRPTMMISTTAMNTALLQWHPPKELPGELLGYRLQYCRAD 852
Query: 1944 GQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPS----N 1999
P D + +T+TGL GT Y L N + T D PS N
Sbjct: 853 EARPNTIDFGKDDQHFTVTGLHKGTTYIFRLAAKNRAGLGEEFEKEIRTPEDLPSGFPQN 912
Query: 2000 LRFLATTPNSLLVSWQPP-----RARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGL 2054
L T ++ ++W PP RI Y + + S + + T T+TGL
Sbjct: 913 LHVTGLTTSTTELAWDPPVLAERNGRIISYTVVFRDINS---QQELQNITTDTRFTLTGL 969
Query: 2055 EPGTEYTIYVIA 2066
+P T Y I V A
Sbjct: 970 KPDTTYDIKVRA 981
Score = 130 bits (326), Expect = 2e-29
Identities = 196/837 (23%), Positives = 330/837 (39%), Gaps = 80/837 (9%)
Query: 862 ANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQ----ETTGTPRSDTVPSPR-DLQFV 916
A +T D P + + + V + T V I E T +P P DL
Sbjct: 269 AEELTKEDEMPVGRNVLELSNVVRSANYTCVAISSLGMIEATAQVTVKALPKPPIDLVVT 328
Query: 917 EVTDVKVTIMWTPPESA-VTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYF 975
E T VT+ W S VT Y + G Q + T + GLSP Y F
Sbjct: 329 ETTATSVTLTWDSGNSEPVTYYGIQYRAAGTEGPF-QEVDGVATTRYSIGGLSPFSEYAF 387
Query: 976 KVFAVS---HGRESKPLTAQ--QTTKLDAPTNLQFVNETDSTVLVRWTP---PRAQITGY 1027
+V AV+ G S+ + A+ + P +Q + ST+LV+W P P + GY
Sbjct: 388 RVLAVNSIGRGPPSEAVRARTGEQAPSSPPRRVQARMLSASTMLVQWEPPEEPNGLVRGY 447
Query: 1028 RLTVGLTRRGQP---RQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTT 1084
R+ R P ++N + + +L P Y++ ++A + P + +
Sbjct: 448 RVYYTPDSRRPPNAWHKHNTDAGLLT-TVGSLLPGITYSLRVLAFTAVGDGPPSPTIQVK 506
Query: 1085 LQPGSSIPP--YNTEV-TETTIVITWTPAPR---IGFKLGVRPSQGGEAPREVTSD-SGS 1137
Q G P + EV ++T I ++W P+ I ++L ++ + +VT D + S
Sbjct: 507 TQQGVPAQPADFQAEVESDTRIQLSWLLPPQERIIMYELVYWAAEDEDQQHKVTFDPTSS 566
Query: 1138 IVVSGLTPGVEYVYTIQVLRD-GQERDAPIVNKVV---TPLSPPTNLHLEANPDTGVLTV 1193
+ L P Y + + D G P + TP +PP + + T V V
Sbjct: 567 YTLEDLKPDTLYRFQLAARSDMGVGVFTPTIEARTAQSTPSAPPQKVMCVSMGSTTV-RV 625
Query: 1194 SW----ERSTTPDITGYRITTTPTNGQ-QGNSLEEVVHADQSSCTFDNLSPGLEYNVSVY 1248
SW S IT Y + +G+ +G + + + + SS L EY V V
Sbjct: 626 SWVPPPADSRNGVITQYSVAYEAVDGEDRGRHVVDGISREHSSWDLVGLEKWTEYRVWVR 685
Query: 1249 TVKD---DKESVPI---SDTIIPEVPQLTDLSFVDITDSSIGLRW-TPLNS---STIIGY 1298
D ES P+ +D +P P + + +++ + W P+ S I GY
Sbjct: 686 AHTDVGPGPESSPVLVRTDEDVPSGPP-RKVEVEPLNSTAVHVYWKLPVPSKQHGQIRGY 744
Query: 1299 RITVVAA--GE--GIPIFEDFVDSSVGYYTVTGLEPGIDYDISV---ITLINGGESAPTT 1351
++T V GE G+PI +D + + T++GL P Y ++V T +G S P
Sbjct: 745 QVTYVRLENGEPRGLPIIQDVMLAEAQETTISGLTPETTYSVTVAAYTTKGDGARSKPKI 804
Query: 1352 LTQQTAVPPPTDLRFTNIGPDTMRVTWAPPPSI--DLTNFLVRYSPVKNEEDVAELSISP 1409
+T AVP + + +T + W PP + +L + ++Y +E +
Sbjct: 805 VTTTGAVPGRPTMMISTTAMNTALLQWHPPKELPGELLGYRLQYCRA-DEARPNTIDFGK 863
Query: 1410 SDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTG----IDFSDITANSF 1465
D +T L GT Y+ +++ +T D P+G + + +T ++
Sbjct: 864 DDQHFTVTGLHKGTTYIFRLAAKNRAGLGEEFEKEIRTPEDLPSGFPQNLHVTGLTTSTT 923
Query: 1466 TVHWIAPRATITGYRIRHHPEHFSGRPREDRVPH--SRNSITLTNLTPGTEYVVSIVALN 1523
+ W P RI + F + + + + TLT L P T Y + + A
Sbjct: 924 ELAWDPPVLAERNGRIISYTVVFRDINSQQELQNITTDTRFTLTGLKPDTTYDIKVRAWT 983
Query: 1524 GREESPLLIGQQSTVSDV----PRDLEVVAATPTSLLISWDAP--AVTVRYYRITYGETG 1577
+ PL QS V ++ V AA TS+L+SW+ P + ++I Y
Sbjct: 984 SKGSGPLSPSIQSRTMPVEQVFAKNFRVAAAMKTSVLLSWEVPDSYKSAVPFKILYNG-- 1041
Query: 1578 GNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEID 1634
Q V G I+ L+P +Y+ + + RG S + + ++ RT D
Sbjct: 1042 -----QSVEVDGHSMRKLIADLQPNTEYS---FVLMNRGSSAGGLQHL-VSIRTAPD 1089
Score = 117 bits (294), Expect = 1e-25
Identities = 183/802 (22%), Positives = 332/802 (41%), Gaps = 100/802 (12%)
Query: 1264 IPEVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIFEDFVDSSVGYY 1323
+P+ P DL + T +S+ L W NS + Y I AAG P F++ + Y
Sbjct: 318 LPKPP--IDLVVTETTATSVTLTWDSGNSEPVTYYGIQYRAAGTEGP-FQEVDGVATTRY 374
Query: 1324 TVTGLEPGIDYDISVITLINGGESAPTTLT-----QQTAVPPPTDLRFTNIGPDTMRVTW 1378
++ GL P +Y V+ + + G P+ +Q PP ++ + TM V W
Sbjct: 375 SIGGLSPFSEYAFRVLAVNSIGRGPPSEAVRARTGEQAPSSPPRRVQARMLSASTMLVQW 434
Query: 1379 APP--PSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLT--NLLPGTEY---VVSVSS 1431
PP P+ + + V Y+P A + +D ++ T +LLPG Y V++ ++
Sbjct: 435 EPPEEPNGLVRGYRVYYTPDSRRPPNAWHKHN-TDAGLLTTVGSLLPGITYSLRVLAFTA 493
Query: 1432 VYEQHESTPLRGRQKTGLDSPTGIDFSDITANS-FTVHWIAP-RATITGYRIRHHPEHFS 1489
V + S ++ + + G+ + +++ +++ + W+ P + I Y + +
Sbjct: 494 VGDGPPSPTIQVKTQQGVPAQPADFQAEVESDTRIQLSWLLPPQERIIMYELVYWAAEDE 553
Query: 1490 GRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREE---SPLLIGQ--QSTVSDVPRD 1544
+ + + +S TL +L P T Y + A + +P + + QST S P+
Sbjct: 554 DQQHKVTFDPT-SSYTLEDLKPDTLYRFQLAARSDMGVGVFTPTIEARTAQSTPSAPPQK 612
Query: 1545 LEVVAATPTSLLISWDAPAVTVR-----YYRITY----GETGGNSPVQEFTVPGSKSTAT 1595
+ V+ T++ +SW P R Y + Y GE G V + S+
Sbjct: 613 VMCVSMGSTTVRVSWVPPPADSRNGVITQYSVAYEAVDGEDRGRHVVDG--ISREHSSWD 670
Query: 1596 ISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPS----QMQVTDVQDNSISV 1651
+ GL+ +Y + V A T G P SS P+ + RT+ D PS +++V + ++ V
Sbjct: 671 LVGLEKWTEYRVWVRAHTDVGPGPESS-PVLV--RTDEDVPSGPPRKVEVEPLNSTAVHV 727
Query: 1652 KW---LPSSS--PVTGYRVTTTP-KNGPG---PTKTKTAGPDQTEMTIEGLQPTVEYVVS 1702
W +PS + GY+VT +NG P + E TI GL P Y V+
Sbjct: 728 YWKLPVPSKQHGQIRGYQVTYVRLENGEPRGLPIIQDVMLAEAQETTISGLTPETTYSVT 787
Query: 1703 VYAQNPSGE---SQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQ---GQVSRYRVT 1756
V A G+ S+P + T + + + +++ + W P+ G++ YR+
Sbjct: 788 VAAYTTKGDGARSKPKIVTTTGAVPGRPTMMISTTAMNTALLQWHPPKELPGELLGYRLQ 847
Query: 1757 YSSPEDGIHELFPAPDGEEDTA-ELQGLRPGSEYTVSVVA-----LHDDMESQPLIGTQS 1810
Y ++ G++D + GL G+ Y + A L ++ E + + +
Sbjct: 848 YCRADEARPNTIDF--GKDDQHFTVTGLHKGTTYIFRLAAKNRAGLGEEFEKE-IRTPED 904
Query: 1811 TAIPAPTDLKFTQVTPTSLSAQWTPP-----NVQLTGYRVRVTPKEKTGPMKEINLAPDS 1865
P +L T +T ++ W PP N ++ Y V +E+
Sbjct: 905 LPSGFPQNLHVTGLTTSTTELAWDPPVLAERNGRIISYTVVF---RDINSQQELQNITTD 961
Query: 1866 SSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPP------RRARVTDATET 1919
+ ++GL T Y++ V A TS+ + + ++++ + P + RV A +T
Sbjct: 962 TRFTLTGLKPDTTYDIKVRAW----TSKGSGPLSPSIQSRTMPVEQVFAKNFRVAAAMKT 1017
Query: 1920 TITISWRTKTETITGFQVDAVPA----NGQTPIQRTIKPDVRSYT--ITGLQPGTDYKIY 1973
++ +SW + AVP NGQ+ ++ D S I LQP T+Y
Sbjct: 1018 SVLLSWE-----VPDSYKSAVPFKILYNGQS-----VEVDGHSMRKLIADLQPNTEYSFV 1067
Query: 1974 LYTLNDNARSSPVVIDASTAID 1995
L +A ++ TA D
Sbjct: 1068 LMNRGSSAGGLQHLVSIRTAPD 1089
Score = 115 bits (289), Expect = 4e-25
Identities = 183/799 (22%), Positives = 303/799 (37%), Gaps = 81/799 (10%)
Query: 1053 LRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPA-- 1110
L N+ ++ YT ++ G E+ V +P I TE T T++ +TW
Sbjct: 287 LSNVVRSANYTCVAISSLGMIEATAQVTVKALPKP--PIDLVVTETTATSVTLTWDSGNS 344
Query: 1111 -PRIGFKLGVRPSQGGEAPREVTSDSGSI--VVSGLTPGVEYVYTIQVLRD-GQERDAPI 1166
P + + R + G E P + + + GL+P EY + + + G+ +
Sbjct: 345 EPVTYYGIQYRAA-GTEGPFQEVDGVATTRYSIGGLSPFSEYAFRVLAVNSIGRGPPSEA 403
Query: 1167 VNKVV---TPLSPPTNLHLEANPDTGVLTVSWERSTTPD--ITGYRITTTPTNGQQGNSL 1221
V P SPP + + +L V WE P+ + GYR+ TP + + N+
Sbjct: 404 VRARTGEQAPSSPPRRVQARMLSASTML-VQWEPPEEPNGLVRGYRVYYTPDSRRPPNAW 462
Query: 1222 EEVVHADQSSCTFDNLSPGLEYNVSVYT---VKDDKESVPISDTIIPEVP-QLTDLSFVD 1277
+ T +L PG+ Y++ V V D S I VP Q D
Sbjct: 463 HKHNTDAGLLTTVGSLLPGITYSLRVLAFTAVGDGPPSPTIQVKTQQGVPAQPADFQAEV 522
Query: 1278 ITDSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDY--D 1335
+D+ I L W II Y + AA + + D + Y T+ L+P Y
Sbjct: 523 ESDTRIQLSWLLPPQERIIMYELVYWAAEDEDQQHKVTFDPTSSY-TLEDLKPDTLYRFQ 581
Query: 1336 ISVITLINGGESAPTT---LTQQTAVPPPTDLRFTNIGPDTMRVTWAPPPSID----LTN 1388
++ + + G PT Q T PP + ++G T+RV+W PPP+ +T
Sbjct: 582 LAARSDMGVGVFTPTIEARTAQSTPSAPPQKVMCVSMGSTTVRVSWVPPPADSRNGVITQ 641
Query: 1389 FLVRYSPVKNEEDVAEL--SISPSDNAVVLTNLLPGTEYVVSV---SSVYEQHESTPLRG 1443
+ V Y V E+ + IS ++ L L TEY V V + V ES+P+
Sbjct: 642 YSVAYEAVDGEDRGRHVVDGISREHSSWDLVGLEKWTEYRVWVRAHTDVGPGPESSPVLV 701
Query: 1444 RQKTGLDS--PTGIDFSDITANSFTVHWIAP-----RATITGYRIRHHPEHFSGRPR--- 1493
R + S P ++ + + + V+W P I GY++ + +G PR
Sbjct: 702 RTDEDVPSGPPRKVEVEPLNSTAVHVYWKLPVPSKQHGQIRGYQVT-YVRLENGEPRGLP 760
Query: 1494 --EDRVPHSRNSITLTNLTPGTEYVVSIVAL----NGREESPLLIGQQSTVSDVPRDLEV 1547
+D + T++ LTP T Y V++ A +G P ++ V P +
Sbjct: 761 IIQDVMLAEAQETTISGLTPETTYSVTVAAYTTKGDGARSKPKIVTTTGAVPGRPTMMIS 820
Query: 1548 VAATPTSLLISWDAPAV---TVRYYRITYGETGGNSPVQEFTVPGSKSTA--TISGLKPG 1602
A T+LL W P + YR+ Y P T+ K T++GL G
Sbjct: 821 TTAMNTALL-QWHPPKELPGELLGYRLQYCRADEARP---NTIDFGKDDQHFTVTGLHKG 876
Query: 1603 VDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLP-----SS 1657
Y + A G K I P + VT + ++ + W P +
Sbjct: 877 TTYIFRLAAKNRAGLGEEFEKEIRTPEDLPSGFPQNLHVTGLTTSTTELAWDPPVLAERN 936
Query: 1658 SPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSV--YAQNPSGESQPL 1715
+ Y V N + T T T+ GL+P Y + V + SG P
Sbjct: 937 GRIISYTVVFRDINSQQELQNITT---DTRFTLTGLKPDTTYDIKVRAWTSKGSGPLSPS 993
Query: 1716 VQTAVTNIDR--PKGLAFTDVDVDSIKIAWESPQGQVSR--YRVTYSSPEDGIHELFPAP 1771
+Q+ +++ K S+ ++WE P S +++ Y+ +
Sbjct: 994 IQSRTMPVEQVFAKNFRVAAAMKTSVLLSWEVPDSYKSAVPFKILYNGQSVEV------- 1046
Query: 1772 DGEEDTAELQGLRPGSEYT 1790
DG + L+P +EY+
Sbjct: 1047 DGHSMRKLIADLQPNTEYS 1065
Score = 104 bits (259), Expect = 1e-21
Identities = 164/774 (21%), Positives = 288/774 (37%), Gaps = 83/774 (10%)
Query: 990 TAQQTTKL--DAPTNLQFVNETDSTVLVRWTPPRAQ-ITGYRLTVGLTRRGQPRQYNVGP 1046
TAQ T K P +L T ++V + W ++ +T Y + P Q G
Sbjct: 310 TAQVTVKALPKPPIDLVVTETTATSVTLTWDSGNSEPVTYYGIQYRAAGTEGPFQEVDGV 369
Query: 1047 SVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGV-FTTLQPGSSIPPYNTE---VTETT 1102
+ ++Y + L P SEY ++A+ P + V T + S PP + ++ +T
Sbjct: 370 ATTRYSIGGLSPFSEYAFRVLAVNSIGRGPPSEAVRARTGEQAPSSPPRRVQARMLSAST 429
Query: 1103 IVITWTPAPR-----IGFKLGVRPS--QGGEAPREVTSDSGSI-VVSGLTPGVEY---VY 1151
+++ W P G+++ P + A + +D+G + V L PG+ Y V
Sbjct: 430 MLVQWEPPEEPNGLVRGYRVYYTPDSRRPPNAWHKHNTDAGLLTTVGSLLPGITYSLRVL 489
Query: 1152 TIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTT 1211
+ DG V + P + E DT + +SW I Y +
Sbjct: 490 AFTAVGDGPPSPTIQVKTQQGVPAQPADFQAEVESDTRI-QLSWLLPPQERIIMYELVYW 548
Query: 1212 PTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPEVPQLT 1271
+ + +V SS T ++L P Y + + D + TI Q T
Sbjct: 549 AAEDE--DQQHKVTFDPTSSYTLEDLKPDTLYRFQL-AARSDMGVGVFTPTIEARTAQST 605
Query: 1272 ------DLSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIFE------DFVDSS 1319
+ V + +++ + W P + + G A E + + D +
Sbjct: 606 PSAPPQKVMCVSMGSTTVRVSWVPPPADSRNGVITQYSVAYEAVDGEDRGRHVVDGISRE 665
Query: 1320 VGYYTVTGLEPGIDYDISVITLIN---GGESAPTTLTQQTAVP--PPTDLRFTNIGPDTM 1374
+ + GLE +Y + V + G ES+P + VP PP + + +
Sbjct: 666 HSSWDLVGLEKWTEYRVWVRAHTDVGPGPESSPVLVRTDEDVPSGPPRKVEVEPLNSTAV 725
Query: 1375 RVTW-APPPSI---DLTNFLVRYSPVKNEED-----VAELSISPSDNAVVLTNLLPGTEY 1425
V W P PS + + V Y ++N E + ++ ++ + + + L P T Y
Sbjct: 726 HVYWKLPVPSKQHGQIRGYQVTYVRLENGEPRGLPIIQDVMLAEAQETTI-SGLTPETTY 784
Query: 1426 VVSVSSVYEQHESTPLRGRQKTGLDSPTG-------IDFSDITANSFTVHWIAPR---AT 1475
V+V++ + + R K + + TG + S N+ + W P+
Sbjct: 785 SVTVAAYTTKGDG----ARSKPKIVTTTGAVPGRPTMMISTTAMNTALLQWHPPKELPGE 840
Query: 1476 ITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN----GREESPLL 1531
+ GYR+++ RP T+T L GT Y+ + A N G E +
Sbjct: 841 LLGYRLQYCRAD-EARPNTIDFGKDDQHFTVTGLHKGTTYIFRLAAKNRAGLGEEFEKEI 899
Query: 1532 IGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVR-----YYRITYGETGGNSPVQEFT 1586
+ S P++L V T ++ ++WD P + R Y + + + +Q T
Sbjct: 900 RTPEDLPSGFPQNLHVTGLTTSTTELAWDPPVLAERNGRIISYTVVFRDINSQQELQNIT 959
Query: 1587 VPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQD 1646
+ + T++GLKP Y I V A T +G P S S E +V
Sbjct: 960 ---TDTRFTLTGLKPDTTYDIKVRAWTSKGSGPLSPSIQSRTMPVEQVFAKNFRVAAAMK 1016
Query: 1647 NSISVKW-LPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEY 1699
S+ + W +P S Y+ K + G ++ I LQP EY
Sbjct: 1017 TSVLLSWEVPDS-----YKSAVPFKILYNGQSVEVDGHSMRKL-IADLQPNTEY 1064
Score = 86.7 bits (213), Expect = 3e-16
Identities = 125/566 (22%), Positives = 223/566 (39%), Gaps = 67/566 (11%)
Query: 628 IQWNAPQPSHISKY-ILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQ 686
+ W P I Y ++ W ++ + K P +SYT++ LKP +Y QL +
Sbjct: 530 LSWLLPPQERIIMYELVYWAAEDEDQQHKVTFDP--TSSYTLEDLKPDTLYRFQLAARSD 587
Query: 687 YGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWV----- 741
G T T+ STP + P ++ S T + VSWV
Sbjct: 588 MGVGVFTPTIEARTAQSTP---------SAPPQKVMCVSMGSTTVR-----VSWVPPPAD 633
Query: 742 SASDTVSGFRVEYELSEEGDEPQYL--DLPSTATSVNIPDLLPGRKYIVNVYQISEDG-- 797
S + ++ + V YE + D +++ + +S ++ L +Y V V ++ G
Sbjct: 634 SRNGVITQYSVAYEAVDGEDRGRHVVDGISREHSSWDLVGLEKWTEYRVWVRAHTDVGPG 693
Query: 798 -EQSLILSTSQTTAPDAPPDPT-VDQVDDTSIVVRW-----SRPQAPITGYRIVYSPSVE 850
E S +L + P PP V+ ++ T++ V W S+ I GY++ Y
Sbjct: 694 PESSPVLVRTDEDVPSGPPRKVEVEPLNSTAVHVYWKLPVPSKQHGQIRGYQVTYVRLEN 753
Query: 851 GSSTELNLPE-----TANSVTLSDLQPGVQYNITIYAVE---ENQESTPVVIQQETTGTP 902
G L + + A T+S L P Y++T+ A + S P ++ TTG
Sbjct: 754 GEPRGLPIIQDVMLAEAQETTISGLTPETTYSVTVAAYTTKGDGARSKPKIV--TTTG-- 809
Query: 903 RSDTVPSPRDLQFVEVTDVKVTIM-WTPPE---SAVTGYRVDVIPVNLPGEHGQRLPISR 958
VP R + T + ++ W PP+ + GYR+ + +
Sbjct: 810 ---AVPG-RPTMMISTTAMNTALLQWHPPKELPGELLGYRLQYCRADEARPNTIDFGKDD 865
Query: 959 NTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPT----NLQFVNETDSTVL 1014
F VTGL G TY F++ A + + + T D P+ NL T ST
Sbjct: 866 QHFT-VTGLHKGTTYIFRLAAKNRAGLGEEFEKEIRTPEDLPSGFPQNLHVTGLTTSTTE 924
Query: 1015 VRWTPP-RAQITGYRLTVGLTRR---GQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIK 1070
+ W PP A+ G ++ + R Q N+ + +++ L L+P + Y + + A
Sbjct: 925 LAWDPPVLAERNGRIISYTVVFRDINSQQELQNI-TTDTRFTLTGLKPDTTYDIKVRAWT 983
Query: 1071 GNQESPKATGVFTTLQPGSSIPPYNTEVT---ETTIVITWTPAPRIGFKLGVRPSQGGEA 1127
P + + + P + N V +T+++++W + + G++
Sbjct: 984 SKGSGPLSPSIQSRTMPVEQVFAKNFRVAAAMKTSVLLSWEVPDSYKSAVPFKILYNGQS 1043
Query: 1128 PREVTSDSGSIVVSGLTPGVEYVYTI 1153
EV S +++ L P EY + +
Sbjct: 1044 V-EVDGHSMRKLIADLQPNTEYSFVL 1068
>gi|112734845 collagen, type XX, alpha 1 [Homo sapiens]
Length = 1284
Score = 152 bits (383), Expect = 5e-36
Identities = 136/474 (28%), Positives = 209/474 (44%), Gaps = 22/474 (4%)
Query: 1258 PISDTIIPEVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIFEDFVD 1317
P + + +P T L +T SSI L WTP + Y I A+ G P E V+
Sbjct: 368 PAAAPALDTLPAPTSLVLSQVTSSSIRLSWTPAPRHPL-KYLIVWRASRGGTPR-EVVVE 425
Query: 1318 SSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTA-VPPPTDLRFTNIGPDTMRV 1376
+ L +Y +SV + GG TA +PPP L + P T+ +
Sbjct: 426 GPAASTELHNLASRTEYLVSVFPIYEGGVGEGLRGLVTTAPLPPPRALTLAAVTPRTVHL 485
Query: 1377 TWAPPPSIDLTNFLVRYSPV--KNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVY- 1433
TW P S T++LVR SP K EE+ E+ + + V+L L PG +Y VSV S+
Sbjct: 486 TWQP--SAGATHYLVRCSPASPKGEEEEREVQVGRPE--VLLDGLEPGRDYEVSVQSLRG 541
Query: 1434 -EQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRP 1492
E E+ +R R T L P + FSD++ ++ V W + R+ + G
Sbjct: 542 PEGSEARGIRARTPT-LAPPRHLGFSDVSHDAARVFWEGAPRPVRLVRVTYVSSE-GGHS 599
Query: 1493 REDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTV-SDVPRDLEVVAAT 1551
+ P + S TL L+ T Y V + L S L G+ +T + P L +
Sbjct: 600 GQTEAPGNATSATLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVTTKKAPSPSQLSMTELP 659
Query: 1552 PTSLLISWDAPAVT-VRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVY 1610
++ ++W A A + V Y+IT+ G E +VPG+ TA + GL +Y +T+
Sbjct: 660 GDAVQLAWVAAAPSGVLVYQITWTPLG-EGKAHEISVPGNLGTAVLPGLGRHTEYDVTIL 718
Query: 1611 AVTGRGDSPASSKPISINYRTEI---DKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTT 1667
A G A S P+S+ Y PS + + +S+ V W P V Y +T
Sbjct: 719 AYYRDG---ARSDPVSLRYTPSTVSRSPPSNLALASETPDSLQVSWTPPLGRVLHYWLTY 775
Query: 1668 TPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVT 1721
P +G GP K+ + ++ +T+ LQ +Y V V A +G S+ + T T
Sbjct: 776 APASGLGPEKSVSVPGARSHVTLPDLQAATKYRVLVSAIYAAGRSEAVSATGQT 829
Score = 146 bits (369), Expect = 2e-34
Identities = 133/449 (29%), Positives = 203/449 (45%), Gaps = 22/449 (4%)
Query: 1449 LDSPTGIDFSDITANSFTVHWI-APRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLT 1507
L +PT + S +T++S + W APR + Y I G PRE V S L
Sbjct: 377 LPAPTSLVLSQVTSSSIRLSWTPAPRHPLK-YLIVWRASR-GGTPREVVVEGPAASTELH 434
Query: 1508 NLTPGTEYVVSIVALNGREESPLLIGQQSTVS-DVPRDLEVVAATPTSLLISWDAPAVTV 1566
NL TEY+VS+ + L G +T PR L + A TP ++ ++W P+
Sbjct: 435 NLASRTEYLVSVFPIYEGGVGEGLRGLVTTAPLPPPRALTLAAVTPRTVHLTWQ-PSAGA 493
Query: 1567 RYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPIS 1626
+Y + +E V + + GL+PG DY ++V ++ G P S+
Sbjct: 494 THYLVRCSPASPKGEEEEREVQVGRPEVLLDGLEPGRDYEVSVQSLRG----PEGSEARG 549
Query: 1627 INYRTE-IDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQ 1685
I RT + P + +DV ++ V W + PV RVT G +T+ G +
Sbjct: 550 IRARTPTLAPPRHLGFSDVSHDAARVFWEGAPRPVRLVRVTYVSSEGGHSGQTEAPG-NA 608
Query: 1686 TEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTN-IDRPKGLAFTDVDVDSIKIAW- 1743
T T+ L + Y V V P G S L T P L+ T++ D++++AW
Sbjct: 609 TSATLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVTTKKAPSPSQLSMTELPGDAVQLAWV 668
Query: 1744 -ESPQGQVSRYRVTYSSPEDG-IHELFPAPDGEEDTAELQGLRPGSEYTVSVVALH-DDM 1800
+P G V Y++T++ +G HE+ + G TA L GL +EY V+++A + D
Sbjct: 669 AAAPSG-VLVYQITWTPLGEGKAHEI--SVPGNLGTAVLPGLGRHTEYDVTILAYYRDGA 725
Query: 1801 ESQP--LIGTQSTAIPAP-TDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMK 1857
S P L T ST +P ++L TP SL WTPP ++ Y + P GP K
Sbjct: 726 RSDPVSLRYTPSTVSRSPPSNLALASETPDSLQVSWTPPLGRVLHYWLTYAPASGLGPEK 785
Query: 1858 EINLAPDSSSVVVSGLMVATKYEVSVYAL 1886
+++ S V + L ATKY V V A+
Sbjct: 786 SVSVPGARSHVTLPDLQAATKYRVLVSAI 814
Score = 136 bits (343), Expect = 2e-31
Identities = 119/472 (25%), Positives = 203/472 (43%), Gaps = 22/472 (4%)
Query: 988 PLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPS 1047
P A L APT+L T S++ + WTP Y + +R G PR+ V
Sbjct: 368 PAAAPALDTLPAPTSLVLSQVTSSSIRLSWTPAPRHPLKYLIVWRASRGGTPREVVVEGP 427
Query: 1048 VSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYN----TEVTETTI 1103
+ L NL +EY VS+ I G+ TT + +PP VT T+
Sbjct: 428 AASTELHNLASRTEYLVSVFPIYEGGVGEGLRGLVTT----APLPPPRALTLAAVTPRTV 483
Query: 1104 VITWTP---APRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQ 1160
+TW P A + +G E REV +++ GL PG +Y ++Q LR +
Sbjct: 484 HLTWQPSAGATHYLVRCSPASPKGEEEEREVQVGRPEVLLDGLEPGRDYEVSVQSLRGPE 543
Query: 1161 ERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNS 1220
+A + L+PP +L ++ V WE + P + R+T + G G+S
Sbjct: 544 GSEARGIRARTPTLAPPRHLGF-SDVSHDAARVFWEGAPRP-VRLVRVTYVSSEG--GHS 599
Query: 1221 LEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTI-IPEVPQLTDLSFVDIT 1279
+ + +S T LS Y V V + S ++ + + P + LS ++
Sbjct: 600 GQTEAPGNATSATLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVTTKKAPSPSQLSMTELP 659
Query: 1280 DSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVI 1339
++ L W S ++ Y+IT GEG E V ++G + GL +YD++++
Sbjct: 660 GDAVQLAWVAAAPSGVLVYQITWTPLGEG-KAHEISVPGNLGTAVLPGLGRHTEYDVTIL 718
Query: 1340 TLI-NGGESAPTTLTQQTAV---PPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSP 1395
+G S P +L + PP++L + PD+++V+W PP + ++ + Y+P
Sbjct: 719 AYYRDGARSDPVSLRYTPSTVSRSPPSNLALASETPDSLQVSWTPPLG-RVLHYWLTYAP 777
Query: 1396 VKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKT 1447
+S+ + + V L +L T+Y V VS++Y S + +T
Sbjct: 778 ASGLGPEKSVSVPGARSHVTLPDLQAATKYRVLVSAIYAAGRSEAVSATGQT 829
Score = 133 bits (335), Expect = 2e-30
Identities = 145/529 (27%), Positives = 230/529 (43%), Gaps = 36/529 (6%)
Query: 1115 FKLGVRPSQGGEA------PREVTSDSG-SIVVSGLTPGVEYVYTIQVLRDGQERDAPIV 1167
F +GV+ + E PR++T S + G G+ Q L+ G R P
Sbjct: 311 FAVGVKNADEAELRLLASPPRDITVHSVLDFLQLGALAGLLSRLICQRLQGGSPRQGPAA 370
Query: 1168 NKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHA 1227
+ L PT+L L + + +SW + + Y I + G G E VV
Sbjct: 371 APALDTLPAPTSLVLSQVTSSSI-RLSWTPAPRHPLK-YLIVWRASRG--GTPREVVVEG 426
Query: 1228 DQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPE-VPQLTDLSFVDITDSSIGLR 1286
+S NL+ EY VSV+ + + + + +P L+ +T ++ L
Sbjct: 427 PAASTELHNLASRTEYLVSVFPIYEGGVGEGLRGLVTTAPLPPPRALTLAAVTPRTVHLT 486
Query: 1287 WTPLNSSTIIGYRITVVAA-GEGIPIFEDFVDSSVGYYTVT--GLEPGIDYDISVITLIN 1343
W P +T R + + GE E+ + VG V GLEPG DY++SV +L
Sbjct: 487 WQPSAGATHYLVRCSPASPKGE-----EEEREVQVGRPEVLLDGLEPGRDYEVSVQSLRG 541
Query: 1344 G-GESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTW--APPPSIDLTNFLVRYSPVKNEE 1400
G A + + PP L F+++ D RV W AP P LVR + V +E
Sbjct: 542 PEGSEARGIRARTPTLAPPRHLGFSDVSHDAARVFWEGAPRPVR-----LVRVTYVSSEG 596
Query: 1401 DVAELSISPSD-NAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTG-LDSPTGIDFS 1458
+ + +P + + L L T Y V V+ +Y S+ L GR T SP+ + +
Sbjct: 597 GHSGQTEAPGNATSATLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVTTKKAPSPSQLSMT 656
Query: 1459 DITANSFTVHWIAPRAT-ITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVV 1517
++ ++ + W+A + + Y+I P G+ E VP + + L L TEY V
Sbjct: 657 ELPGDAVQLAWVAAAPSGVLVYQITWTPLG-EGKAHEISVPGNLGTAVLPGLGRHTEYDV 715
Query: 1518 SIVAL--NGREESPLLIGQQ-STVS-DVPRDLEVVAATPTSLLISWDAPAVTVRYYRITY 1573
+I+A +G P+ + STVS P +L + + TP SL +SW P V +Y +TY
Sbjct: 716 TILAYYRDGARSDPVSLRYTPSTVSRSPPSNLALASETPDSLQVSWTPPLGRVLHYWLTY 775
Query: 1574 GETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASS 1622
G P + +VPG++S T+ L+ Y + V A+ G S A S
Sbjct: 776 APASGLGPEKSVSVPGARSHVTLPDLQAATKYRVLVSAIYAAGRSEAVS 824
Score = 114 bits (286), Expect = 9e-25
Identities = 129/516 (25%), Positives = 215/516 (41%), Gaps = 41/516 (7%)
Query: 1615 RGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPG 1674
+G SP P + + P+ + ++ V +SI + W P+ Y + G
Sbjct: 360 QGGSPRQG-PAAAPALDTLPAPTSLVLSQVTSSSIRLSWTPAPRHPLKYLIVWRASRGGT 418
Query: 1675 PTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTN-IDRPKGLAFTD 1733
P + GP + L EY+VSV+ G + L T + P+ L
Sbjct: 419 PREVVVEGP-AASTELHNLASRTEYLVSVFPIYEGGVGEGLRGLVTTAPLPPPRALTLAA 477
Query: 1734 VDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQ---------GLR 1784
V ++ + W+ P + Y V S +P GEE+ E+Q GL
Sbjct: 478 VTPRTVHLTWQ-PSAGATHYLVRCSPA---------SPKGEEEEREVQVGRPEVLLDGLE 527
Query: 1785 PGSEYTVSVVALHDDMESQPL-IGTQSTAIPAPTDLKFTQVTPTSLSAQW--TPPNVQLT 1841
PG +Y VSV +L S+ I ++ + P L F+ V+ + W P V+L
Sbjct: 528 PGRDYEVSVQSLRGPEGSEARGIRARTPTLAPPRHLGFSDVSHDAARVFWEGAPRPVRL- 586
Query: 1842 GYRVRVTPKEKTGPMKEINLAP-DSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVT 1900
VRVT G AP +++S + L +T Y V V L S G VT
Sbjct: 587 ---VRVTYVSSEGGHSGQTEAPGNATSATLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVT 643
Query: 1901 TLENVSPPRRARVTDATETTITISWRTKTET-ITGFQVDAVPANGQTPIQRTIKPDVRSY 1959
T + SP + + +T+ + ++W + + +Q+ P + ++ ++ +
Sbjct: 644 TKKAPSPSQLS-MTELPGDAVQLAWVAAAPSGVLVYQITWTPLGEGKAHEISVPGNLGTA 702
Query: 1960 TITGLQPGTDYKIYLYTL-NDNARSSPVVI---DASTAIDAPSNLRFLATTPNSLLVSWQ 2015
+ GL T+Y + + D ARS PV + ++ + PSNL + TP+SL VSW
Sbjct: 703 VLPGLGRHTEYDVTILAYYRDGARSDPVSLRYTPSTVSRSPPSNLALASETPDSLQVSWT 762
Query: 2016 PPRARITGYIIKY-EKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSE 2074
PP R+ Y + Y G P + V P + T+ L+ T+Y + V A+ +SE
Sbjct: 763 PPLGRVLHYWLTYAPASGLGPEKSVSVP-GARSHVTLPDLQAATKYRVLVSAIYAAGRSE 821
Query: 2075 PLIGRKKTDELPQLVTLPHPNLHGPEILDVPSTVQK 2110
+ +T P L P +L G +++ S V+K
Sbjct: 822 AVSATGQT-ACPAL--RPDGSLPGFDLMVAFSLVEK 854
Score = 102 bits (255), Expect = 4e-21
Identities = 130/522 (24%), Positives = 196/522 (37%), Gaps = 52/522 (9%)
Query: 599 CQPLQTYPSSSGPVEVFITETPSQP----------NSHPIQWNAPQPSHISKYILRWRPK 648
CQ LQ GP +T P +S + W P P H KY++ WR
Sbjct: 356 CQRLQGGSPRQGPAAAPALDTLPAPTSLVLSQVTSSSIRLSWT-PAPRHPLKYLIVWRAS 414
Query: 649 NSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTS 708
G +E + G S + L Y + I + G E R TT+ P
Sbjct: 415 RG-GTPREVVVEGPAASTELHNLASRTEYLVSVFPIYEGGVGEGLR-GLVTTAPLPP--- 469
Query: 709 NTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDL 768
P T +VT T ++W S + + V + E + ++
Sbjct: 470 -----------PRALTLAAVTPRTVH---LTW-QPSAGATHYLVRCSPASPKGEEEEREV 514
Query: 769 PSTATSVNIPDLLPGRKYIVNVYQI--SEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTS 826
V + L PGR Y V+V + E E I + + T AP P V +
Sbjct: 515 QVGRPEVLLDGLEPGRDYEVSVQSLRGPEGSEARGIRARTPTLAP--PRHLGFSDVSHDA 572
Query: 827 IVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEEN 886
V W P+ R+ Y S G S + P A S TL L Y + + +
Sbjct: 573 ARVFWEGAPRPVRLVRVTYVSSEGGHSGQTEAPGNATSATLGPLSSSTTYTVRVTCLYPG 632
Query: 887 QESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMW-TPPESAVTGYRVDVIPVN 945
S+ + TG + PSP L E+ V + W S V Y++ P+
Sbjct: 633 GGSSTL------TGRVTTKKAPSPSQLSMTELPGDAVQLAWVAAAPSGVLVYQITWTPLG 686
Query: 946 LPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFA-VSHGRESKPLTAQ---QTTKLDAPT 1001
H +P + T A + GL Y + A G S P++ + T P+
Sbjct: 687 EGKAHEISVPGNLGT-AVLPGLGRHTEYDVTILAYYRDGARSDPVSLRYTPSTVSRSPPS 745
Query: 1002 NLQFVNETDSTVLVRWTPPRAQITGYRLTVG-LTRRGQPRQYNVGPSVSKYPLRNLQPAS 1060
NL +ET ++ V WTPP ++ Y LT + G + +V + S L +LQ A+
Sbjct: 746 NLALASETPDSLQVSWTPPLGRVLHYWLTYAPASGLGPEKSVSVPGARSHVTLPDLQAAT 805
Query: 1061 EYTVSLVAI--KGNQESPKATG--VFTTLQPGSSIPPYNTEV 1098
+Y V + AI G E+ ATG L+P S+P ++ V
Sbjct: 806 KYRVLVSAIYAAGRSEAVSATGQTACPALRPDGSLPGFDLMV 847
Score = 91.3 bits (225), Expect = 1e-17
Identities = 111/478 (23%), Positives = 191/478 (39%), Gaps = 23/478 (4%)
Query: 895 QQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRL 954
+Q P DT+P+P L +VT + + WTP Y + V + G + +
Sbjct: 365 RQGPAAAPALDTLPAPTSLVLSQVTSSSIRLSWTPAPRHPLKYLI-VWRASRGGTPREVV 423
Query: 955 PISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTT-KLDAPTNLQFVNETDSTV 1013
E+ L+ Y VF + G + L TT L P L T TV
Sbjct: 424 VEGPAASTELHNLASRTEYLVSVFPIYEGGVGEGLRGLVTTAPLPPPRALTLAAVTPRTV 483
Query: 1014 LVRWTPPRAQITGYRLTVG-LTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGN 1072
+ W P A T Y + + +G+ + V + L L+P +Y VS+ +++G
Sbjct: 484 HLTW-QPSAGATHYLVRCSPASPKGEEEEREVQVGRPEVLLDGLEPGRDYEVSVQSLRG- 541
Query: 1073 QESPKATGVFTTLQPGSSIPPYN---TEVTETTIVITWTPAPRIGFKLGVR--PSQGGEA 1127
E +A G+ + + PP + ++V+ + W APR + V S+GG +
Sbjct: 542 PEGSEARGI--RARTPTLAPPRHLGFSDVSHDAARVFWEGAPRPVRLVRVTYVSSEGGHS 599
Query: 1128 PR-EVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSP-PTNLHLEAN 1185
+ E ++ S + L+ Y + L G + + +V T +P P+ L +
Sbjct: 600 GQTEAPGNATSATLGPLSSSTTYTVRVTCLYPG-GGSSTLTGRVTTKKAPSPSQLSMTEL 658
Query: 1186 PDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNV 1245
P V ++W + + Y+IT TP +G + E V + + L EY+V
Sbjct: 659 PGDAV-QLAWVAAAPSGVLVYQITWTPLG--EGKAHEISVPGNLGTAVLPGLGRHTEYDV 715
Query: 1246 SVYT-VKDDKESVPISDTIIPEVPQL---TDLSFVDITDSSIGLRWTPLNSSTIIGYRIT 1301
++ +D S P+S P ++L+ T S+ + WTP ++ Y +T
Sbjct: 716 TILAYYRDGARSDPVSLRYTPSTVSRSPPSNLALASETPDSLQVSWTP-PLGRVLHYWLT 774
Query: 1302 VVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAVP 1359
A P V + + T+ L+ Y + V + G S + T QTA P
Sbjct: 775 YAPASGLGPEKSVSVPGARSHVTLPDLQAATKYRVLVSAIYAAGRSEAVSATGQTACP 832
Score = 74.7 bits (182), Expect = 1e-12
Identities = 92/414 (22%), Positives = 159/414 (38%), Gaps = 34/414 (8%)
Query: 590 YGRGIGEWHCQPLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSH-ISKYILRWRPK 648
Y G+GE + T P P +T P + + W QPS + Y++R P
Sbjct: 450 YEGGVGEGLRGLVTTAPL---PPPRALTLAAVTPRTVHLTW---QPSAGATHYLVRCSPA 503
Query: 649 NSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTS 708
+ G +E + + GL+PG YE + S++ E T + + P
Sbjct: 504 SPKGEEEEREVQVGRPEVLLDGLEPGRDYEVSVQSLRGPEGSEARGIRARTPTLAPP--- 560
Query: 709 NTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDL 768
++++ + V W A V RV Y SE G Q +
Sbjct: 561 ---------------RHLGFSDVSHDAARVFWEGAPRPVRLVRVTYVSSEGGHSGQ-TEA 604
Query: 769 PSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIV 828
P ATS + L Y V V + G S + T +P ++ ++ ++
Sbjct: 605 PGNATSATLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVTTKKAPSPSQLSMTELPGDAVQ 664
Query: 829 VRW-SRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYA-VEEN 886
+ W + + + Y+I ++P EG + E+++P + L L +Y++TI A +
Sbjct: 665 LAWVAAAPSGVLVYQITWTPLGEGKAHEISVPGNLGTAVLPGLGRHTEYDVTILAYYRDG 724
Query: 887 QESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVN- 945
S PV ++ TP + + P +L T + + WTPP V Y + P +
Sbjct: 725 ARSDPVSLRY----TPSTVSRSPPSNLALASETPDSLQVSWTPPLGRVLHYWLTYAPASG 780
Query: 946 LPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDA 999
L E +P +R + + L Y V A+ S+ ++A T A
Sbjct: 781 LGPEKSVSVPGAR-SHVTLPDLQAATKYRVLVSAIYAAGRSEAVSATGQTACPA 833
Score = 65.5 bits (158), Expect = 6e-10
Identities = 66/271 (24%), Positives = 113/271 (41%), Gaps = 23/271 (8%)
Query: 604 TYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHL 663
T + P ++ +TE P ++ + W A PS + Y + W P G+ E ++PG+L
Sbjct: 643 TTKKAPSPSQLSMTELPG--DAVQLAWVAAAPSGVLVYQITWTPLGE-GKAHEISVPGNL 699
Query: 664 NSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVA 723
+ + GL Y+ +++ + G + + S T +TV+ +P S L
Sbjct: 700 GTAVLPGLGRHTEYDVTILAYYRDGAR--------SDPVSLRYTPSTVS--RSPPSNLAL 749
Query: 724 TSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPG 783
SE T S VSW V + + Y + + + +P + V +PDL
Sbjct: 750 ASE-----TPDSLQVSWTPPLGRVLHYWLTYAPASGLGPEKSVSVPGARSHVTLPDLQAA 804
Query: 784 RKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYR- 842
KY V V I G + +T QT P PD ++ D ++V +S + R
Sbjct: 805 TKYRVLVSAIYAAGRSEAVSATGQTACPALRPDGSLPGFD---LMVAFSLVEKAYASIRG 861
Query: 843 IVYSPSVEGSSTELNLPETAN-SVTLSDLQP 872
+ PS G + L + A + +SD+ P
Sbjct: 862 VAMEPSAFGGTPTFTLFKDAQLTRRVSDVYP 892
Score = 32.3 bits (72), Expect = 5.9
Identities = 15/64 (23%), Positives = 27/64 (42%)
Query: 2212 ISWAPFQDTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQR 2271
++W P + Y++ C P E + V L GL G Y + V++L+ +
Sbjct: 485 LTWQPSAGATHYLVRCSPASPKGEEEEREVQVGRPEVLLDGLEPGRDYEVSVQSLRGPEG 544
Query: 2272 HKVR 2275
+ R
Sbjct: 545 SEAR 548
>gi|18860892 protein tyrosine phosphatase, receptor type, D isoform 3
precursor [Homo sapiens]
Length = 1903
Score = 149 bits (377), Expect = 3e-35
Identities = 170/673 (25%), Positives = 286/673 (42%), Gaps = 81/673 (12%)
Query: 1458 SDITANSFTVHWIAPRAT-ITGYRIRHHPEHFSGRPRE-DRVPHSRNSITLTNLTPGTEY 1515
++ TA S T+ W + ++ Y I+H P++ +E D V +R S+ L+P ++Y
Sbjct: 332 TESTATSITLTWDSGNPEPVSYYIIQHKPKNSEELYKEIDGVATTRYSVA--GLSPYSDY 389
Query: 1516 VVSIVALN----GREESPLLIG-QQSTVSDVPRDLEVVAATPTSLLISW---DAPAVTVR 1567
+VA+N G P+L + S PRD++ + T++L+ W + P ++
Sbjct: 390 EFRVVAVNNIGRGPPSEPVLTQTSEQAPSSAPRDVQARMLSSTTILVQWKEPEEPNGQIQ 449
Query: 1568 YYRITY--GETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPI 1625
YR+ Y T + + V S+ T TI L P Y++ V A T GD P SS
Sbjct: 450 GYRVYYTMDPTQHVNNWMKHNVADSQIT-TIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQ 508
Query: 1626 SINYRTEIDKPSQMQVTDVQDNSISVKWL-PSSSPVTGYRVTTTPKNGPGPTKTKTAGPD 1684
I +P + + SI + W P S + Y + K+G + +
Sbjct: 509 VITQTGVPGQPLNFKAEPESETSILLSWTPPRSDTIANYELVY--KDGEHGEEQRITIEP 566
Query: 1685 QTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDR-----PKGLAFTDVDVDSI 1739
T ++GL+P Y + A++P G + + + P+ ++ T SI
Sbjct: 567 GTSYRLQGLKPNSLYYFRLAARSPQGLGASTAEISARTMQSKPSAPPQDISCTSPSSTSI 626
Query: 1740 KIAWESP-----QGQVSRYRVTYSS---PEDGIHELFPAPDGEEDTAE--LQGLRPGSEY 1789
++W+ P G ++ Y + Y++ +D HE+ P DT + L+ L +EY
Sbjct: 627 LVSWQPPPVEKQNGIITEYSIKYTAVDGEDDKPHEILGIP---SDTTKYLLEQLEKWTEY 683
Query: 1790 TVSVVALHDDM----ESQPLIGTQSTAIPA--PTDLKFTQVTPTSLSAQWTPP-----NV 1838
++V A H D+ ES ++ + +P+ P ++ V TS+ W P +
Sbjct: 684 RITVTA-HTDVGPGPESLSVLIRTNEDVPSGPPRKVEVEAVNSTSVKVSWRSPVPNKQHG 742
Query: 1839 QLTGYRVRVTPKEKTGP-----MKEINLAPDSSSVVVSGLMVATKYEVSVYALK---DTL 1890
Q+ GY+V E P +K++ LA D+ +++SGL T Y ++V A D
Sbjct: 743 QIRGYQVHYVRMENGEPKGQPMLKDVMLA-DAQDMIISGLQPETSYSLTVTAYTTKGDGA 801
Query: 1891 TSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTET---ITGFQV-----DAVPA 1942
S+P +V+T V R + T I W +T + G+++ D P
Sbjct: 802 RSKPK--LVSTTGAVPGKPRLVINHTQMNTALIQWHPPVDTFGPLQGYRLKFGRKDMEPL 859
Query: 1943 NGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPS---- 1998
T ++ + K D +T T + G Y L N +V + S + P+
Sbjct: 860 ---TTLEFSEKED--HFTATDIHKGASYVFRLSARNKVGFGEEMVKEISIPEEVPTGFPQ 914
Query: 1999 NLRFLATTPNSLLVSWQPP-----RARITGYIIKYEKPGSPPREVVPRPRPGVTEATITG 2053
NL TT S+ +SWQPP IT Y + Y P + P T T+TG
Sbjct: 915 NLHSEGTTSTSVQLSWQPPVLAERNGIITKYTLLYRDINIPLLPMEQLIVPADTTMTLTG 974
Query: 2054 LEPGTEYTIYVIA 2066
L+P T Y + V A
Sbjct: 975 LKPDTTYDVKVRA 987
Score = 146 bits (369), Expect = 2e-34
Identities = 234/1018 (22%), Positives = 390/1018 (38%), Gaps = 123/1018 (12%)
Query: 930 PESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSP--GVTYYFKVFAVSHGRESK 987
P+ +T ++ D +PV+ +G+ + +E G +P G + G+
Sbjct: 153 PDPEITWFK-DFLPVDTSNNNGR----IKQLRSESIGGTPIRGALQIEQSEESDQGKYEC 207
Query: 988 PLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQIT--------GYRLTVGLTRRGQP 1039
T T+ AP NL +V E VR PPR I G + + G P
Sbjct: 208 VATNSAGTRYSAPANL-YVRELRE---VRRVPPRFSIPPTNHEIMPGGSVNITCVAVGSP 263
Query: 1040 RQY----------------NVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFT 1083
Y +G +V + L +++ ++ YT ++ G E+ V
Sbjct: 264 MPYVKWMLGAEDLTPEDDMPIGRNVLE--LNDVRQSANYTCVAMSTLGVIEAIAQITVKA 321
Query: 1084 TLQPGSSIPPYNTEVTETTIVITW---TPAPRIGFKLGVRPSQGGEAPREVTSDSGS-IV 1139
+P + P TE T T+I +TW P P + + +P E +E+ + +
Sbjct: 322 LPKPPGT--PVVTESTATSITLTWDSGNPEPVSYYIIQHKPKNSEELYKEIDGVATTRYS 379
Query: 1140 VSGLTPGVEYVYTIQVLRD---GQERDAPIVNKVV--TPLSPPTNLHLEANPDTGVLTVS 1194
V+GL+P +Y + + + + G + P++ + P S P ++ T +L V
Sbjct: 380 VAGLSPYSDYEFRVVAVNNIGRGPPSE-PVLTQTSEQAPSSAPRDVQARMLSSTTIL-VQ 437
Query: 1195 WERSTTPD--ITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVY---T 1249
W+ P+ I GYR+ T Q N+ + AD T NL P Y+V V +
Sbjct: 438 WKEPEEPNGQIQGYRVYYTMDPTQHVNNWMKHNVADSQITTIGNLVPQKTYSVKVLAFTS 497
Query: 1250 VKDDKESVPISDTIIPEVP-QLTDLSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGEG 1308
+ D S I VP Q + +++SI L WTP S TI Y + G
Sbjct: 498 IGDGPLSSDIQVITQTGVPGQPLNFKAEPESETSILLSWTPPRSDTIANYELVYKDGEHG 557
Query: 1309 IPIFEDFVDSSVGY-YTVTGLEPGIDYDISVITLINGGESAPTT-----LTQQTAVPPPT 1362
E + G Y + GL+P Y + G A T Q PP
Sbjct: 558 E---EQRITIEPGTSYRLQGLKPNSLYYFRLAARSPQGLGASTAEISARTMQSKPSAPPQ 614
Query: 1363 DLRFTNIGPDTMRVTWAPPPSID----LTNFLVRYSPVKNEEDVA-ELSISPSDNA-VVL 1416
D+ T+ ++ V+W PPP +T + ++Y+ V E+D E+ PSD +L
Sbjct: 615 DISCTSPSSTSILVSWQPPPVEKQNGIITEYSIKYTAVDGEDDKPHEILGIPSDTTKYLL 674
Query: 1417 TNLLPGTEYVVSVSSVYE-----QHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIA 1471
L TEY ++V++ + + S +R + P ++ + + S V W +
Sbjct: 675 EQLEKWTEYRITVTAHTDVGPGPESLSVLIRTNEDVPSGPPRKVEVEAVNSTSVKVSWRS 734
Query: 1472 P-----RATITGYRIRHHPEHFSGRPR-----EDRVPHSRNSITLTNLTPGTEYVVSIVA 1521
P I GY++ H+ +G P+ +D + + ++ L P T Y +++ A
Sbjct: 735 PVPNKQHGQIRGYQV-HYVRMENGEPKGQPMLKDVMLADAQDMIISGLQPETSYSLTVTA 793
Query: 1522 L----NGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVT---VRYYRITYG 1574
+G P L+ V PR L + + LI W P T ++ YR+ +G
Sbjct: 794 YTTKGDGARSKPKLVSTTGAVPGKPR-LVINHTQMNTALIQWHPPVDTFGPLQGYRLKFG 852
Query: 1575 ETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEID 1634
P+ + T + + G Y + A G K ISI
Sbjct: 853 RKD-MEPLTTLEFSEKEDHFTATDIHKGASYVFRLSARNKVGFGEEMVKEISIPEEVPTG 911
Query: 1635 KPSQMQVTDVQDNSISVKWLPS-----SSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMT 1689
P + S+ + W P + +T Y + N P + P T MT
Sbjct: 912 FPQNLHSEGTTSTSVQLSWQPPVLAERNGIITKYTLLYRDINIPLLPMEQLIVPADTTMT 971
Query: 1690 IEGLQPTVEYVVSVYAQNPSGES--QPLVQTAVTNIDR--PKGLAFTDVDVDSIKIAWES 1745
+ GL+P Y V V A G P VQ +D+ K V S+ ++WE
Sbjct: 972 LTGLKPDTTYDVKVRAHTSKGPGPYSPSVQFRTLPVDQVFAKNFHVKAVMKTSVLLSWEI 1031
Query: 1746 PQGQVSR--YRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQ 1803
P+ S +++ Y +DG ++ DG + L+P Y+ L + S
Sbjct: 1032 PENYNSAMPFKILY---DDG--KMVEEVDGRATQKLIVNLKPEKSYS---FVLTNRGNSA 1083
Query: 1804 PLIGTQSTAIPAPTDL--KFTQVTPTSLSAQWT------PPNVQLTGYRVRVTPKEKT 1853
+ + TA AP L K + T+L T P N + GY + + P +K+
Sbjct: 1084 GGLQHRVTAKTAPDVLRTKPAFIGKTNLDGMITVQLPEVPANENIKGYYIIIVPLKKS 1141
Score = 125 bits (314), Expect = 5e-28
Identities = 161/700 (23%), Positives = 292/700 (41%), Gaps = 70/700 (10%)
Query: 696 DFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSAS-DTVSGFRVEY 754
++T + ST + T P + VTE TA+S ++W S + + VS + +++
Sbjct: 299 NYTCVAMSTLGVIEAIAQITVKALPKPPGTPVVTESTATSITLTWDSGNPEPVSYYIIQH 358
Query: 755 ELSEEGDEPQYLDLPSTATS-VNIPDLLPGRKYIVNVYQISEDG----EQSLILSTSQTT 809
+ + E Y ++ AT+ ++ L P Y V ++ G + ++ TS+
Sbjct: 359 K--PKNSEELYKEIDGVATTRYSVAGLSPYSDYEFRVVAVNNIGRGPPSEPVLTQTSEQA 416
Query: 810 APDAPPDPTVDQVDDTSIVVRWSRPQAP---ITGYRIVYS--PSVEGSSTELNLPETANS 864
AP D + T+I+V+W P+ P I GYR+ Y+ P+ ++ + +
Sbjct: 417 PSSAPRDVQARMLSSTTILVQWKEPEEPNGQIQGYRVYYTMDPTQHVNNWMKHNVADSQI 476
Query: 865 VTLSDLQPGVQYNITIYA---VEENQESTPV-VIQQETTGTPRSDTVPSPRDLQFVEVTD 920
T+ +L P Y++ + A + + S+ + VI Q TG P P + + ++
Sbjct: 477 TTIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQ--TGVP-----GQPLNFKAEPESE 529
Query: 921 VKVTIMWTPPES-AVTGYRVDVIPVNLPGEHG--QRLPISRNTFAEVTGLSPGVTYYFKV 977
+ + WTPP S + Y + V GEHG QR+ I T + GL P YYF++
Sbjct: 530 TSILLSWTPPRSDTIANYEL----VYKDGEHGEEQRITIEPGTSYRLQGLKPNSLYYFRL 585
Query: 978 FAVSH---GRESKPLTAQ--QTTKLDAPTNLQFVNETDSTVLVRWTPPRAQ-----ITGY 1027
A S G + ++A+ Q+ P ++ + + +++LV W PP + IT Y
Sbjct: 586 AARSPQGLGASTAEISARTMQSKPSAPPQDISCTSPSSTSILVSWQPPPVEKQNGIITEY 645
Query: 1028 --RLTVGLTRRGQPRQYNVGPS-VSKYPLRNLQPASEYTVSLVAIKGNQESPKATGV-FT 1083
+ T +P + PS +KY L L+ +EY +++ A P++ V
Sbjct: 646 SIKYTAVDGEDDKPHEILGIPSDTTKYLLEQLEKWTEYRITVTAHTDVGPGPESLSVLIR 705
Query: 1084 TLQPGSSIPPYNTE---VTETTIVITW-TPAPR------IGFKLGVRPSQGGEAPRE--- 1130
T + S PP E V T++ ++W +P P G+++ + GE +
Sbjct: 706 TNEDVPSGPPRKVEVEAVNSTSVKVSWRSPVPNKQHGQIRGYQVHYVRMENGEPKGQPML 765
Query: 1131 ---VTSDSGSIVVSGLTPGVEYVYTIQVLR---DGQERDAPIVNKVVTPLSPPTNLHLEA 1184
+ +D+ +++SGL P Y T+ DG +V+ P +
Sbjct: 766 KDVMLADAQDMIISGLQPETSYSLTVTAYTTKGDGARSKPKLVSTTGAVPGKPRLVINHT 825
Query: 1185 NPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYN 1244
+T ++ T + GYR+ + + +LE D + T + +
Sbjct: 826 QMNTALIQWHPPVDTFGPLQGYRLKFGRKDMEPLTTLEFSEKEDHFTATDIHKGASYVFR 885
Query: 1245 VSVYTVKDDKESVPISDTIIPEVPQ--LTDLSFVDITDSSIGLRWTP--LNSSTIIGYRI 1300
+S E + +I EVP +L T +S+ L W P L I +
Sbjct: 886 LSARNKVGFGEEMVKEISIPEEVPTGFPQNLHSEGTTSTSVQLSWQPPVLAERNGIITKY 945
Query: 1301 TVVAAGEGIPI--FEDFVDSSVGYYTVTGLEPGIDYDISV 1338
T++ IP+ E + + T+TGL+P YD+ V
Sbjct: 946 TLLYRDINIPLLPMEQLIVPADTTMTLTGLKPDTTYDVKV 985
Score = 109 bits (272), Expect = 4e-23
Identities = 185/811 (22%), Positives = 303/811 (37%), Gaps = 106/811 (13%)
Query: 619 TPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNS-YTIKGLKPGVVY 677
T S S + W++ P +S YI++ +PKNS +KE I G + Y++ GL P Y
Sbjct: 332 TESTATSITLTWDSGNPEPVSYYIIQHKPKNSEELYKE--IDGVATTRYSVAGLSPYSDY 389
Query: 678 EGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFV 737
E +++++ G S PV T T E P S +++++ +
Sbjct: 390 EFRVVAVNNIGR----------GPPSEPVL--TQTSEQAPSS--APRDVQARMLSSTTIL 435
Query: 738 VSWVSASD---TVSGFRVEYELSEEGDEPQYLDLPSTATSV-NIPDLLPGRKYIVNVYQI 793
V W + + G+RV Y + ++ + + I +L+P + Y V V
Sbjct: 436 VQWKEPEEPNGQIQGYRVYYTMDPTQHVNNWMKHNVADSQITTIGNLVPQKTYSVKVLAF 495
Query: 794 SEDGEQSL---ILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQA-PITGYRIVYSPSV 849
+ G+ L I +QT P P + + +TSI++ W+ P++ I Y +VY
Sbjct: 496 TSIGDGPLSSDIQVITQTGVPGQPLNFKAEPESETSILLSWTPPRSDTIANYELVYKDGE 555
Query: 850 EGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPS 909
G + + E S L L+P Y + A + + + + T +S
Sbjct: 556 HGEEQRITI-EPGTSYRLQGLKPNSLYYFRLAA--RSPQGLGASTAEISARTMQSKPSAP 612
Query: 910 PRDLQFVEVTDVKVTIMWTPP-----ESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEV 964
P+D+ + + + W PP +T Y + V+ GE + E+
Sbjct: 613 PQDISCTSPSSTSILVSWQPPPVEKQNGIITEYSIKYTAVD--GEDDKP--------HEI 662
Query: 965 TGLSPGVTYY----------FKVFAVSH---GRESKPLTAQQTTKLDAPT------NLQF 1005
G+ T Y +++ +H G + L+ T D P+ ++
Sbjct: 663 LGIPSDTTKYLLEQLEKWTEYRITVTAHTDVGPGPESLSVLIRTNEDVPSGPPRKVEVEA 722
Query: 1006 VNETDSTVLVRWTPP-----RAQITGYRLTVGLTRRGQPRQYNVGPSV-----SKYPLRN 1055
VN T +V V W P QI GY++ G+P+ + V +
Sbjct: 723 VNST--SVKVSWRSPVPNKQHGQIRGYQVHYVRMENGEPKGQPMLKDVMLADAQDMIISG 780
Query: 1056 LQPASEY--TVSLVAIKGNQESPKATGVFTT-LQPGSSIPPYNTEVTETTIVITWTP--- 1109
LQP + Y TV+ KG+ K V TT PG N T +I W P
Sbjct: 781 LQPETSYSLTVTAYTTKGDGARSKPKLVSTTGAVPGKPRLVIN-HTQMNTALIQWHPPVD 839
Query: 1110 --APRIGFKLGV-RPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRD---GQERD 1163
P G++L R E + + + G YV+ + G+E
Sbjct: 840 TFGPLQGYRLKFGRKDMEPLTTLEFSEKEDHFTATDIHKGASYVFRLSARNKVGFGEEMV 899
Query: 1164 APIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPD----ITGYRITTTPTNGQQGN 1219
I P P NLH E T V +SW+ + IT Y + N
Sbjct: 900 KEISIPEEVPTGFPQNLHSEGTTSTSV-QLSWQPPVLAERNGIITKYTLLYRDINIPLLP 958
Query: 1220 SLEEVVHADQSSCTFDNLSPGLEYNVSV--YTVKDDKESVPISDTIIPEVPQLTDLSF-- 1275
+ +V AD ++ T L P Y+V V +T K P V Q+ +F
Sbjct: 959 MEQLIVPAD-TTMTLTGLKPDTTYDVKVRAHTSKGPGPYSPSVQFRTLPVDQVFAKNFHV 1017
Query: 1276 VDITDSSIGLRW-TPLNSSTIIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDY 1334
+ +S+ L W P N ++ + ++I +G + E VD + L+P Y
Sbjct: 1018 KAVMKTSVLLSWEIPENYNSAMPFKILY---DDGKMVEE--VDGRATQKLIVNLKPEKSY 1072
Query: 1335 DISVITLINGGESAPTTLTQQTAVPPPTDLR 1365
L N G SA + TA P LR
Sbjct: 1073 S---FVLTNRGNSAGGLQHRVTAKTAPDVLR 1100
Score = 99.4 bits (246), Expect = 4e-20
Identities = 164/749 (21%), Positives = 272/749 (36%), Gaps = 93/749 (12%)
Query: 1577 GGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKP 1636
G E +P ++ ++ ++ +YT + G ++ A I + P
Sbjct: 272 GAEDLTPEDDMPIGRNVLELNDVRQSANYTCVAMSTLGVIEAIAQ-----ITVKALPKPP 326
Query: 1637 SQMQVTDVQDNSISVKWLPSS-SPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQP 1695
VT+ SI++ W + PV+ Y + PKN K + G T ++ GL P
Sbjct: 327 GTPVVTESTATSITLTWDSGNPEPVSYYIIQHKPKNSEELYK-EIDGVATTRYSVAGLSP 385
Query: 1696 TVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDV-----DSIKIAW---ESPQ 1747
+Y V A N G P ++ A DV +I + W E P
Sbjct: 386 YSDYEFRVVAVNNIGRGPPSEPVLTQTSEQAPSSAPRDVQARMLSSTTILVQWKEPEEPN 445
Query: 1748 GQVSRYRVTYS-SPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVA---LHDDMESQ 1803
GQ+ YRV Y+ P ++ + + L P Y+V V+A + D S
Sbjct: 446 GQIQGYRVYYTMDPTQHVNNWMKHNVADSQITTIGNLVPQKTYSVKVLAFTSIGDGPLSS 505
Query: 1804 PLIGTQSTAIPA-PTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLA 1862
+ T +P P + K + TS+ WTPP V + G + I +
Sbjct: 506 DIQVITQTGVPGQPLNFKAEPESETSILLSWTPPRSDTIANYELVYKDGEHGEEQRITIE 565
Query: 1863 PDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVS----------PPRRAR 1912
P +S + GL + Y L +R QG+ + +S PP+
Sbjct: 566 P-GTSYRLQGLKPNSLYYFR-------LAARSPQGLGASTAEISARTMQSKPSAPPQDIS 617
Query: 1913 VTDATETTITISWRT-----KTETITGFQVDAVPANGQTPIQRTI---KPDVRSYTITGL 1964
T + T+I +SW+ + IT + + +G+ I D Y + L
Sbjct: 618 CTSPSSTSILVSWQPPPVEKQNGIITEYSIKYTAVDGEDDKPHEILGIPSDTTKYLLEQL 677
Query: 1965 QPGTDYKIYLYTLND---NARSSPVVIDASTAIDA--PSNLRFLATTPNSLLVSWQPP-- 2017
+ T+Y+I + D S V+I + + + P + A S+ VSW+ P
Sbjct: 678 EKWTEYRITVTAHTDVGPGPESLSVLIRTNEDVPSGPPRKVEVEAVNSTSVKVSWRSPVP 737
Query: 2018 ---RARITGYIIKY------EKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALK 2068
+I GY + Y E G P + V + I+GL+P T Y++ V A
Sbjct: 738 NKQHGQIRGYQVHYVRMENGEPKGQPMLKDVMLA--DAQDMIISGLQPETSYSLTVTAYT 795
Query: 2069 NNQKSEPLIGRKKTDELPQLVTLPHPNLHGPEILDVPSTVQKTPFVT-HPGYDTGNGIQ- 2126
R K P+LV+ + G L + T T + HP DT +Q
Sbjct: 796 TKGDG----ARSK----PKLVSTTGA-VPGKPRLVINHTQMNTALIQWHPPVDTFGPLQG 846
Query: 2127 ---LPGTSGQQPSVGQQMIFEEHGFRRTTPPTTATPIRHRPRPYPPNVGEEIQIGHIPRE 2183
G +P + +E F TAT I H+ Y + ++G
Sbjct: 847 YRLKFGRKDMEPLTTLEFSEKEDHF-------TATDI-HKGASYVFRLSARNKVGFGEEM 898
Query: 2184 DVDYHLYPHGP-GLNPNASTGQEALSQTTISWAP------FQDTSEYIISCHPVGTDEEP 2236
+ + P G N + + +SW P ++Y + + P
Sbjct: 899 VKEISIPEEVPTGFPQNLHSEGTTSTSVQLSWQPPVLAERNGIITKYTLLYRDINIPLLP 958
Query: 2237 LQFRVPGTSTSATLTGLTRGATYNIIVEA 2265
++ + T+ TLTGL TY++ V A
Sbjct: 959 MEQLIVPADTTMTLTGLKPDTTYDVKVRA 987
>gi|109633041 protein tyrosine phosphatase, receptor type, F isoform 1
precursor [Homo sapiens]
Length = 1907
Score = 147 bits (371), Expect = 1e-34
Identities = 173/640 (27%), Positives = 262/640 (40%), Gaps = 80/640 (12%)
Query: 1493 REDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPR---DLEVVA 1549
+ED +P RN + L+N+ Y ++ G E+ Q TV +P+ DL V
Sbjct: 274 KEDEMPVGRNVLELSNVVRSANYTCVAISSLGMIEATA----QVTVKALPKPPIDLVVTE 329
Query: 1550 ATPTSLLISWDAP-AVTVRYYRITYGETGGNSPVQEFTVPGSKSTA-TISGLKPGVDYTI 1607
T TS+ ++WD+ + V YY I Y G P QE V G +T +I GL P +Y
Sbjct: 330 TTATSVTLTWDSGNSEPVTYYGIQYRAAGTEGPFQE--VDGVATTRYSIGGLSPFSEYAF 387
Query: 1608 TVYAVTGRGDSPASSKPISINYRTEIDKPS----QMQVTDVQDNSISVKWLPSSSP---V 1660
V AV G P S ++ RT PS ++Q + +++ V+W P P V
Sbjct: 388 RVLAVNSIGRGPPSE---AVRARTGEQAPSSPPRRVQARMLSASTMLVQWEPPEEPNGLV 444
Query: 1661 TGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEG-LQPTVEYVVSVYAQNPSGESQPLVQTA 1719
GYRV TP + P D +T G L P + Y + V A G+ P
Sbjct: 445 RGYRVYYTPDSRRPPNAWHKHNTDAGLLTTVGSLLPGITYSLRVLAFTAVGDGPPSPTIQ 504
Query: 1720 V-TNIDRPKGLAFTDVDVDS---IKIAWE-SPQGQVSRYRVTY--SSPEDGIHELFPAPD 1772
V T P A +V+S I+++W PQ ++ Y + Y + ED H++ P
Sbjct: 505 VKTQQGVPAQPADFQAEVESDTRIQLSWLLPPQERIIMYELVYWAAEDEDQQHKVTFDPT 564
Query: 1773 GEEDTAELQGLRPGSEYTVSVVALHD--------DMESQPLIGTQSTAIPAPTDLKFTQV 1824
+ L+ L+P + Y + A D +E++ QST P + +
Sbjct: 565 S---SYTLEDLKPDTLYRFQLAARSDMGVGVFTPTIEART---AQSTPSAPPQKVMCVSM 618
Query: 1825 TPTSLSAQWTPP-----NVQLTGYRV--RVTPKEKTGPMKEINLAPDSSSVVVSGLMVAT 1877
T++ W PP N +T Y V E G ++ + SS + GL T
Sbjct: 619 GSTTVRVSWVPPPADSRNGVITQYSVAYEAVDGEDRGRHVVDGISREHSSWDLVGLEKWT 678
Query: 1878 KYEVSVYALKDTLTSRPAQGV-VTTLENV--SPPRRARVTDATETTITISWRTKTET--- 1931
+Y V V A D + V V T E+V PPR+ V T + + W+ +
Sbjct: 679 EYRVWVRAHTDVGPGPESSPVLVRTDEDVPSGPPRKVEVEPLNSTAVHVYWKLPVPSKQH 738
Query: 1932 --ITGFQVDAVPANGQTPIQRTIKPDVR--------------SYTITGLQPGTDYKIYLY 1975
I G+QV V P I DV TI+GL P T Y + +
Sbjct: 739 GQIRGYQVTYVRLENGEPRGLPIIQDVMLAEAQWRPEESEDYETTISGLTPETTYSVTVA 798
Query: 1976 ---TLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPR---ARITGYIIKYE 2029
T D ARS P ++ + A+ + T N+ L+ W PP+ + GY ++Y
Sbjct: 799 AYTTKGDGARSKPKIVTTTGAVPGRPTMMISTTAMNTALLQWHPPKELPGELLGYRLQYC 858
Query: 2030 KPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKN 2069
+ + + T+TGL GT Y I+ +A KN
Sbjct: 859 RADEARPNTIDFGKDD-QHFTVTGLHKGTTY-IFRLAAKN 896
Score = 141 bits (355), Expect = 9e-33
Identities = 169/737 (22%), Positives = 290/737 (39%), Gaps = 77/737 (10%)
Query: 1348 APTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSI 1407
A +T + PP DL T ++ +TW S +T + ++Y E E+
Sbjct: 309 ATAQVTVKALPKPPIDLVVTETTATSVTLTWDSGNSEPVTYYGIQYRAAGTEGPFQEVD- 367
Query: 1408 SPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRG-RQKTGLDSPTG----IDFSDITA 1462
+ + L P +EY V +V P R +TG +P+ + ++A
Sbjct: 368 GVATTRYSIGGLSPFSEYAFRVLAVNSIGRGPPSEAVRARTGEQAPSSPPRRVQARMLSA 427
Query: 1463 NSFTVHWIAPR---ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLT---NLTPGTEYV 1516
++ V W P + GYR+ + P+ S RP H+ ++ LT +L PG Y
Sbjct: 428 STMLVQWEPPEEPNGLVRGYRVYYTPD--SRRPPNAWHKHNTDAGLLTTVGSLLPGITYS 485
Query: 1517 VSIVALNGREESP----LLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVT-VRYYRI 1571
+ ++A + P + + Q V P D + + T + +SW P + Y +
Sbjct: 486 LRVLAFTAVGDGPPSPTIQVKTQQGVPAQPADFQAEVESDTRIQLSWLLPPQERIIMYEL 545
Query: 1572 TYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRT 1631
Y + T + S+ T+ LKP Y + + R D +I RT
Sbjct: 546 VYWAAEDEDQQHKVTFDPT-SSYTLEDLKPDTLYR---FQLAARSDMGVGVFTPTIEART 601
Query: 1632 EIDKPS----QMQVTDVQDNSISVKWLPSSSP-----VTGYRVTTTPKNGPGPTKTKTAG 1682
PS ++ + ++ V W+P + +T Y V +G + G
Sbjct: 602 AQSTPSAPPQKVMCVSMGSTTVRVSWVPPPADSRNGVITQYSVAYEAVDGEDRGRHVVDG 661
Query: 1683 --PDQTEMTIEGLQPTVEYVVSVYAQN---PSGESQPLVQTAVTNIDR--PKGLAFTDVD 1735
+ + + GL+ EY V V A P ES P++ ++ P+ + ++
Sbjct: 662 ISREHSSWDLVGLEKWTEYRVWVRAHTDVGPGPESSPVLVRTDEDVPSGPPRKVEVEPLN 721
Query: 1736 VDSIKIAWESP-----QGQVSRYRVTYSSPEDGIHELFPA------------PDGEED-T 1777
++ + W+ P GQ+ Y+VTY E+G P P+ ED
Sbjct: 722 STAVHVYWKLPVPSKQHGQIRGYQVTYVRLENGEPRGLPIIQDVMLAEAQWRPEESEDYE 781
Query: 1778 AELQGLRPGSEYTVSVVALH---DDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWT 1834
+ GL P + Y+V+V A D S+P I T + A+P + + + QW
Sbjct: 782 TTISGLTPETTYSVTVAAYTTKGDGARSKPKIVTTTGAVPGRPTMMISTTAMNTALLQWH 841
Query: 1835 PPNV---QLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLT 1891
PP +L GYR++ ++ P I+ D V+GL T Y + A
Sbjct: 842 PPKELPGELLGYRLQYCRADEARP-NTIDFGKDDQHFTVTGLHKGTTYIFRLAAKNRAGL 900
Query: 1892 SRPAQGVVTTLENVSP--PRRARVTDATETTITISW-----RTKTETITGFQVDAVPANG 1944
+ + T E++ P+ VT T +T ++W + I + V N
Sbjct: 901 GEEFEKEIRTPEDLPSGFPQNLHVTGLTTSTTELAWDPPVLAERNGRIISYTVVFRDINS 960
Query: 1945 QTPIQRTIKPDVRSYTITGLQPGTDY--KIYLYTLNDNARSSPVVIDASTAIDA--PSNL 2000
Q +Q I D R +T+TGL+P T Y K+ +T + SP + + ++ N
Sbjct: 961 QQELQN-ITTDTR-FTLTGLKPDTTYDIKVRAWTSKGSGPLSPSIQSRTMPVEQVFAKNF 1018
Query: 2001 RFLATTPNSLLVSWQPP 2017
R A S+L+SW+ P
Sbjct: 1019 RVAAAMKTSVLLSWEVP 1035
Score = 127 bits (320), Expect = 1e-28
Identities = 178/740 (24%), Positives = 294/740 (39%), Gaps = 91/740 (12%)
Query: 1399 EEDVAELSISPSDNAVVLTNLLPGTEYV-VSVSSV--YEQHESTPLRGRQKTGLDSPTGI 1455
EE E + N + L+N++ Y V++SS+ E ++ K +D +
Sbjct: 270 EELTKEDEMPVGRNVLELSNVVRSANYTCVAISSLGMIEATAQVTVKALPKPPID----L 325
Query: 1456 DFSDITANSFTVHWIAPRAT-ITGYRIRHHPEHFSGRPRE-DRVPHSRNSITLTNLTPGT 1513
++ TA S T+ W + + +T Y I++ G +E D V +R SI L+P +
Sbjct: 326 VVTETTATSVTLTWDSGNSEPVTYYGIQYRAAGTEGPFQEVDGVATTRYSIG--GLSPFS 383
Query: 1514 EYVVSIVALNGREESP------LLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVT-- 1565
EY ++A+N P G+Q+ S PR ++ + +++L+ W+ P
Sbjct: 384 EYAFRVLAVNSIGRGPPSEAVRARTGEQAP-SSPPRRVQARMLSASTMLVQWEPPEEPNG 442
Query: 1566 -VRYYRITYGETGGNSPV---QEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPAS 1621
VR YR+ Y P + T G +T + L PG+ Y++ V A T GD P S
Sbjct: 443 LVRGYRVYYTPDSRRPPNAWHKHNTDAGLLTT--VGSLLPGITYSLRVLAFTAVGDGPPS 500
Query: 1622 SKPISINYRTEIDKPSQ---MQVTDVQDNSISVKWL-PSSSPVTGYRVTTTPKNGPGPTK 1677
+I +T+ P+Q Q D I + WL P + Y +
Sbjct: 501 P---TIQVKTQQGVPAQPADFQAEVESDTRIQLSWLLPPQERIIMYELVYWAAEDEDQQH 557
Query: 1678 TKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGES--QPLVQTAV---TNIDRPKGLAFT 1732
T P + T+E L+P Y + A++ G P ++ T P+ +
Sbjct: 558 KVTFDPTSS-YTLEDLKPDTLYRFQLAARSDMGVGVFTPTIEARTAQSTPSAPPQKVMCV 616
Query: 1733 DVDVDSIKIAWESP-----QGQVSRYRVTYSSP--EDGIHELFPAPDGEEDTAELQGLRP 1785
+ +++++W P G +++Y V Y + ED + E + +L GL
Sbjct: 617 SMGSTTVRVSWVPPPADSRNGVITQYSVAYEAVDGEDRGRHVVDGISREHSSWDLVGLEK 676
Query: 1786 GSEYTVSVVALHDDM----ESQPLIGTQSTAIPA--PTDLKFTQVTPTSLSAQWTPP--- 1836
+EY V V A H D+ ES P++ +P+ P ++ + T++ W P
Sbjct: 677 WTEYRVWVRA-HTDVGPGPESSPVLVRTDEDVPSGPPRKVEVEPLNSTAVHVYWKLPVPS 735
Query: 1837 --NVQLTGYRVRVTPKEKTGP----------MKEINLAPDSSS---VVVSGLMVATKYEV 1881
+ Q+ GY+V E P + E P+ S +SGL T Y V
Sbjct: 736 KQHGQIRGYQVTYVRLENGEPRGLPIIQDVMLAEAQWRPEESEDYETTISGLTPETTYSV 795
Query: 1882 SVYALK---DTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTET---ITGF 1935
+V A D S+P +VTT V ++ T + W E + G+
Sbjct: 796 TVAAYTTKGDGARSKPK--IVTTTGAVPGRPTMMISTTAMNTALLQWHPPKELPGELLGY 853
Query: 1936 QVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAID 1995
++ A+ P D + +T+TGL GT Y L N + T D
Sbjct: 854 RLQYCRADEARPNTIDFGKDDQHFTVTGLHKGTTYIFRLAAKNRAGLGEEFEKEIRTPED 913
Query: 1996 APS----NLRFLATTPNSLLVSWQPP-----RARITGYIIKYEKPGSPPREVVPRPRPGV 2046
PS NL T ++ ++W PP RI Y + + S + +
Sbjct: 914 LPSGFPQNLHVTGLTTSTTELAWDPPVLAERNGRIISYTVVFRDINS---QQELQNITTD 970
Query: 2047 TEATITGLEPGTEYTIYVIA 2066
T T+TGL+P T Y I V A
Sbjct: 971 TRFTLTGLKPDTTYDIKVRA 990
Score = 124 bits (312), Expect = 9e-28
Identities = 198/846 (23%), Positives = 332/846 (39%), Gaps = 89/846 (10%)
Query: 862 ANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQ----ETTGTPRSDTVPSPR-DLQFV 916
A +T D P + + + V + T V I E T +P P DL
Sbjct: 269 AEELTKEDEMPVGRNVLELSNVVRSANYTCVAISSLGMIEATAQVTVKALPKPPIDLVVT 328
Query: 917 EVTDVKVTIMWTPPESA-VTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYF 975
E T VT+ W S VT Y + G Q + T + GLSP Y F
Sbjct: 329 ETTATSVTLTWDSGNSEPVTYYGIQYRAAGTEGPF-QEVDGVATTRYSIGGLSPFSEYAF 387
Query: 976 KVFAVS---HGRESKPLTAQ--QTTKLDAPTNLQFVNETDSTVLVRWTP---PRAQITGY 1027
+V AV+ G S+ + A+ + P +Q + ST+LV+W P P + GY
Sbjct: 388 RVLAVNSIGRGPPSEAVRARTGEQAPSSPPRRVQARMLSASTMLVQWEPPEEPNGLVRGY 447
Query: 1028 RLTVGLTRRGQP---RQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTT 1084
R+ R P ++N + + +L P Y++ ++A + P + +
Sbjct: 448 RVYYTPDSRRPPNAWHKHNTDAGLLT-TVGSLLPGITYSLRVLAFTAVGDGPPSPTIQVK 506
Query: 1085 LQPGSSIPP--YNTEV-TETTIVITWTPAPR---IGFKLGVRPSQGGEAPREVTSD-SGS 1137
Q G P + EV ++T I ++W P+ I ++L ++ + +VT D + S
Sbjct: 507 TQQGVPAQPADFQAEVESDTRIQLSWLLPPQERIIMYELVYWAAEDEDQQHKVTFDPTSS 566
Query: 1138 IVVSGLTPGVEYVYTIQVLRD-GQERDAPIVNKVV---TPLSPPTNLHLEANPDTGVLTV 1193
+ L P Y + + D G P + TP +PP + + T V V
Sbjct: 567 YTLEDLKPDTLYRFQLAARSDMGVGVFTPTIEARTAQSTPSAPPQKVMCVSMGSTTV-RV 625
Query: 1194 SW----ERSTTPDITGYRITTTPTNGQ-QGNSLEEVVHADQSSCTFDNLSPGLEYNVSVY 1248
SW S IT Y + +G+ +G + + + + SS L EY V V
Sbjct: 626 SWVPPPADSRNGVITQYSVAYEAVDGEDRGRHVVDGISREHSSWDLVGLEKWTEYRVWVR 685
Query: 1249 TVKD---DKESVPI---SDTIIPEVPQLTDLSFVDITDSSIGLRW-TPLNS---STIIGY 1298
D ES P+ +D +P P + + +++ + W P+ S I GY
Sbjct: 686 AHTDVGPGPESSPVLVRTDEDVPSGPP-RKVEVEPLNSTAVHVYWKLPVPSKQHGQIRGY 744
Query: 1299 RITVVAA--GE--GIPIFEDFV--------DSSVGY-YTVTGLEPGIDYDISV---ITLI 1342
++T V GE G+PI +D + + S Y T++GL P Y ++V T
Sbjct: 745 QVTYVRLENGEPRGLPIIQDVMLAEAQWRPEESEDYETTISGLTPETTYSVTVAAYTTKG 804
Query: 1343 NGGESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAPPPSI--DLTNFLVRYSPVKNEE 1400
+G S P +T AVP + + +T + W PP + +L + ++Y +E
Sbjct: 805 DGARSKPKIVTTTGAVPGRPTMMISTTAMNTALLQWHPPKELPGELLGYRLQYCRA-DEA 863
Query: 1401 DVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTG----ID 1456
+ D +T L GT Y+ +++ +T D P+G +
Sbjct: 864 RPNTIDFGKDDQHFTVTGLHKGTTYIFRLAAKNRAGLGEEFEKEIRTPEDLPSGFPQNLH 923
Query: 1457 FSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPH--SRNSITLTNLTPGTE 1514
+ +T ++ + W P RI + F + + + + TLT L P T
Sbjct: 924 VTGLTTSTTELAWDPPVLAERNGRIISYTVVFRDINSQQELQNITTDTRFTLTGLKPDTT 983
Query: 1515 YVVSIVALNGREESPLLIGQQSTVSDV----PRDLEVVAATPTSLLISWDAP--AVTVRY 1568
Y + + A + PL QS V ++ V AA TS+L+SW+ P +
Sbjct: 984 YDIKVRAWTSKGSGPLSPSIQSRTMPVEQVFAKNFRVAAAMKTSVLLSWEVPDSYKSAVP 1043
Query: 1569 YRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISIN 1628
++I Y Q V G I+ L+P +Y+ + + RG S + + ++
Sbjct: 1044 FKILYNG-------QSVEVDGHSMRKLIADLQPNTEYS---FVLMNRGSSAGGLQHL-VS 1092
Query: 1629 YRTEID 1634
RT D
Sbjct: 1093 IRTAPD 1098
Score = 115 bits (289), Expect = 4e-25
Identities = 182/811 (22%), Positives = 333/811 (41%), Gaps = 109/811 (13%)
Query: 1264 IPEVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIFEDFVDSSVGYY 1323
+P+ P DL + T +S+ L W NS + Y I AAG P F++ + Y
Sbjct: 318 LPKPP--IDLVVTETTATSVTLTWDSGNSEPVTYYGIQYRAAGTEGP-FQEVDGVATTRY 374
Query: 1324 TVTGLEPGIDYDISVITLINGGESAPTTLT-----QQTAVPPPTDLRFTNIGPDTMRVTW 1378
++ GL P +Y V+ + + G P+ +Q PP ++ + TM V W
Sbjct: 375 SIGGLSPFSEYAFRVLAVNSIGRGPPSEAVRARTGEQAPSSPPRRVQARMLSASTMLVQW 434
Query: 1379 APP--PSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLT--NLLPGTEY---VVSVSS 1431
PP P+ + + V Y+P A + +D ++ T +LLPG Y V++ ++
Sbjct: 435 EPPEEPNGLVRGYRVYYTPDSRRPPNAWHKHN-TDAGLLTTVGSLLPGITYSLRVLAFTA 493
Query: 1432 VYEQHESTPLRGRQKTGLDSPTGIDFSDITANS-FTVHWIAP-RATITGYRIRHHPEHFS 1489
V + S ++ + + G+ + +++ +++ + W+ P + I Y + +
Sbjct: 494 VGDGPPSPTIQVKTQQGVPAQPADFQAEVESDTRIQLSWLLPPQERIIMYELVYWAAEDE 553
Query: 1490 GRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREE---SPLLIGQ--QSTVSDVPRD 1544
+ + + +S TL +L P T Y + A + +P + + QST S P+
Sbjct: 554 DQQHKVTFDPT-SSYTLEDLKPDTLYRFQLAARSDMGVGVFTPTIEARTAQSTPSAPPQK 612
Query: 1545 LEVVAATPTSLLISWDAPAVTVR-----YYRITY----GETGGNSPVQEFTVPGSKSTAT 1595
+ V+ T++ +SW P R Y + Y GE G V + S+
Sbjct: 613 VMCVSMGSTTVRVSWVPPPADSRNGVITQYSVAYEAVDGEDRGRHVVDG--ISREHSSWD 670
Query: 1596 ISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPS----QMQVTDVQDNSISV 1651
+ GL+ +Y + V A T G P SS P+ + RT+ D PS +++V + ++ V
Sbjct: 671 LVGLEKWTEYRVWVRAHTDVGPGPESS-PVLV--RTDEDVPSGPPRKVEVEPLNSTAVHV 727
Query: 1652 KW---LPSSS--PVTGYRVTTT------PKNGP-------GPTKTKTAGPDQTEMTIEGL 1693
W +PS + GY+VT P+ P + + + E TI GL
Sbjct: 728 YWKLPVPSKQHGQIRGYQVTYVRLENGEPRGLPIIQDVMLAEAQWRPEESEDYETTISGL 787
Query: 1694 QPTVEYVVSVYAQNPSGE---SQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQ--- 1747
P Y V+V A G+ S+P + T + + + +++ + W P+
Sbjct: 788 TPETTYSVTVAAYTTKGDGARSKPKIVTTTGAVPGRPTMMISTTAMNTALLQWHPPKELP 847
Query: 1748 GQVSRYRVTYSSPEDGIHELFPAPDGEEDTA-ELQGLRPGSEYTVSVVA-----LHDDME 1801
G++ YR+ Y ++ G++D + GL G+ Y + A L ++ E
Sbjct: 848 GELLGYRLQYCRADEARPNTIDF--GKDDQHFTVTGLHKGTTYIFRLAAKNRAGLGEEFE 905
Query: 1802 SQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPP-----NVQLTGYRVRVTPKEKTGPM 1856
+ + + P +L T +T ++ W PP N ++ Y V
Sbjct: 906 KE-IRTPEDLPSGFPQNLHVTGLTTSTTELAWDPPVLAERNGRIISYTVVF---RDINSQ 961
Query: 1857 KEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPP------RR 1910
+E+ + ++GL T Y++ V A TS+ + + ++++ + P +
Sbjct: 962 QELQNITTDTRFTLTGLKPDTTYDIKVRAW----TSKGSGPLSPSIQSRTMPVEQVFAKN 1017
Query: 1911 ARVTDATETTITISWRTKTETITGFQVDAVPA----NGQTPIQRTIKPDVRSYT--ITGL 1964
RV A +T++ +SW + AVP NGQ+ ++ D S I L
Sbjct: 1018 FRVAAAMKTSVLLSWE-----VPDSYKSAVPFKILYNGQS-----VEVDGHSMRKLIADL 1067
Query: 1965 QPGTDYKIYLYTLNDNARSSPVVIDASTAID 1995
QP T+Y L +A ++ TA D
Sbjct: 1068 QPNTEYSFVLMNRGSSAGGLQHLVSIRTAPD 1098
Score = 110 bits (274), Expect = 2e-23
Identities = 184/808 (22%), Positives = 304/808 (37%), Gaps = 90/808 (11%)
Query: 1053 LRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPA-- 1110
L N+ ++ YT ++ G E+ V +P I TE T T++ +TW
Sbjct: 287 LSNVVRSANYTCVAISSLGMIEATAQVTVKALPKP--PIDLVVTETTATSVTLTWDSGNS 344
Query: 1111 -PRIGFKLGVRPSQGGEAPREVTSDSGSI--VVSGLTPGVEYVYTIQVLRD-GQERDAPI 1166
P + + R + G E P + + + GL+P EY + + + G+ +
Sbjct: 345 EPVTYYGIQYRAA-GTEGPFQEVDGVATTRYSIGGLSPFSEYAFRVLAVNSIGRGPPSEA 403
Query: 1167 VNKVV---TPLSPPTNLHLEANPDTGVLTVSWERSTTPD--ITGYRITTTPTNGQQGNSL 1221
V P SPP + + +L V WE P+ + GYR+ TP + + N+
Sbjct: 404 VRARTGEQAPSSPPRRVQARMLSASTML-VQWEPPEEPNGLVRGYRVYYTPDSRRPPNAW 462
Query: 1222 EEVVHADQSSCTFDNLSPGLEYNVSVYT---VKDDKESVPISDTIIPEVP-QLTDLSFVD 1277
+ T +L PG+ Y++ V V D S I VP Q D
Sbjct: 463 HKHNTDAGLLTTVGSLLPGITYSLRVLAFTAVGDGPPSPTIQVKTQQGVPAQPADFQAEV 522
Query: 1278 ITDSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDY--D 1335
+D+ I L W II Y + AA + + D + Y T+ L+P Y
Sbjct: 523 ESDTRIQLSWLLPPQERIIMYELVYWAAEDEDQQHKVTFDPTSSY-TLEDLKPDTLYRFQ 581
Query: 1336 ISVITLINGGESAPTT---LTQQTAVPPPTDLRFTNIGPDTMRVTWAPPPSID----LTN 1388
++ + + G PT Q T PP + ++G T+RV+W PPP+ +T
Sbjct: 582 LAARSDMGVGVFTPTIEARTAQSTPSAPPQKVMCVSMGSTTVRVSWVPPPADSRNGVITQ 641
Query: 1389 FLVRYSPVKNEEDVAEL--SISPSDNAVVLTNLLPGTEYVVSV---SSVYEQHESTPLRG 1443
+ V Y V E+ + IS ++ L L TEY V V + V ES+P+
Sbjct: 642 YSVAYEAVDGEDRGRHVVDGISREHSSWDLVGLEKWTEYRVWVRAHTDVGPGPESSPVLV 701
Query: 1444 RQKTGLDS--PTGIDFSDITANSFTVHWIAP-----RATITGYRIRHHPEHFSGRPR--- 1493
R + S P ++ + + + V+W P I GY++ + +G PR
Sbjct: 702 RTDEDVPSGPPRKVEVEPLNSTAVHVYWKLPVPSKQHGQIRGYQVT-YVRLENGEPRGLP 760
Query: 1494 ----------EDRVPHSRN-SITLTNLTPGTEYVVSIVAL----NGREESPLLIGQQSTV 1538
+ R S + T++ LTP T Y V++ A +G P ++ V
Sbjct: 761 IIQDVMLAEAQWRPEESEDYETTISGLTPETTYSVTVAAYTTKGDGARSKPKIVTTTGAV 820
Query: 1539 SDVPRDLEVVAATPTSLLISWDAPAV---TVRYYRITYGETGGNSPVQEFTVPGSKSTA- 1594
P + A T+LL W P + YR+ Y P T+ K
Sbjct: 821 PGRPTMMISTTAMNTALL-QWHPPKELPGELLGYRLQYCRADEARP---NTIDFGKDDQH 876
Query: 1595 -TISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKW 1653
T++GL G Y + A G K I P + VT + ++ + W
Sbjct: 877 FTVTGLHKGTTYIFRLAAKNRAGLGEEFEKEIRTPEDLPSGFPQNLHVTGLTTSTTELAW 936
Query: 1654 LP-----SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSV--YAQ 1706
P + + Y V N + T T T+ GL+P Y + V +
Sbjct: 937 DPPVLAERNGRIISYTVVFRDINSQQELQNITT---DTRFTLTGLKPDTTYDIKVRAWTS 993
Query: 1707 NPSGESQPLVQTAVTNIDR--PKGLAFTDVDVDSIKIAWESPQGQVSR--YRVTYSSPED 1762
SG P +Q+ +++ K S+ ++WE P S +++ Y+
Sbjct: 994 KGSGPLSPSIQSRTMPVEQVFAKNFRVAAAMKTSVLLSWEVPDSYKSAVPFKILYNGQSV 1053
Query: 1763 GIHELFPAPDGEEDTAELQGLRPGSEYT 1790
+ DG + L+P +EY+
Sbjct: 1054 EV-------DGHSMRKLIADLQPNTEYS 1074
Score = 105 bits (261), Expect = 7e-22
Identities = 168/782 (21%), Positives = 286/782 (36%), Gaps = 90/782 (11%)
Query: 990 TAQQTTKL--DAPTNLQFVNETDSTVLVRWTPPRAQ-ITGYRLTVGLTRRGQPRQYNVGP 1046
TAQ T K P +L T ++V + W ++ +T Y + P Q G
Sbjct: 310 TAQVTVKALPKPPIDLVVTETTATSVTLTWDSGNSEPVTYYGIQYRAAGTEGPFQEVDGV 369
Query: 1047 SVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGV-FTTLQPGSSIPPYNTE---VTETT 1102
+ ++Y + L P SEY ++A+ P + V T + S PP + ++ +T
Sbjct: 370 ATTRYSIGGLSPFSEYAFRVLAVNSIGRGPPSEAVRARTGEQAPSSPPRRVQARMLSAST 429
Query: 1103 IVITWTPAPR-----IGFKLGVRPS--QGGEAPREVTSDSGSI-VVSGLTPGVEY---VY 1151
+++ W P G+++ P + A + +D+G + V L PG+ Y V
Sbjct: 430 MLVQWEPPEEPNGLVRGYRVYYTPDSRRPPNAWHKHNTDAGLLTTVGSLLPGITYSLRVL 489
Query: 1152 TIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTT 1211
+ DG V + P + E DT + +SW I Y +
Sbjct: 490 AFTAVGDGPPSPTIQVKTQQGVPAQPADFQAEVESDTRI-QLSWLLPPQERIIMYELVYW 548
Query: 1212 PTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPEVPQLT 1271
+ + +V SS T ++L P Y + + D + TI Q T
Sbjct: 549 AAEDE--DQQHKVTFDPTSSYTLEDLKPDTLYRFQL-AARSDMGVGVFTPTIEARTAQST 605
Query: 1272 ------DLSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIFE------DFVDSS 1319
+ V + +++ + W P + + G A E + + D +
Sbjct: 606 PSAPPQKVMCVSMGSTTVRVSWVPPPADSRNGVITQYSVAYEAVDGEDRGRHVVDGISRE 665
Query: 1320 VGYYTVTGLEPGIDYDISVITLIN---GGESAPTTLTQQTAVP--PPTDLRFTNIGPDTM 1374
+ + GLE +Y + V + G ES+P + VP PP + + +
Sbjct: 666 HSSWDLVGLEKWTEYRVWVRAHTDVGPGPESSPVLVRTDEDVPSGPPRKVEVEPLNSTAV 725
Query: 1375 RVTW-APPPS-------------IDLTNFLVRYSPVKNEEDVAELSISP---SDNAVVLT 1417
V W P PS + L N R P+ + +AE P D ++
Sbjct: 726 HVYWKLPVPSKQHGQIRGYQVTYVRLENGEPRGLPIIQDVMLAEAQWRPEESEDYETTIS 785
Query: 1418 NLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTG-------IDFSDITANSFTVHWI 1470
L P T Y V+V++ + + R K + + TG + S N+ + W
Sbjct: 786 GLTPETTYSVTVAAYTTKGDG----ARSKPKIVTTTGAVPGRPTMMISTTAMNTALLQWH 841
Query: 1471 APR---ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN---- 1523
P+ + GYR+++ RP T+T L GT Y+ + A N
Sbjct: 842 PPKELPGELLGYRLQYCRAD-EARPNTIDFGKDDQHFTVTGLHKGTTYIFRLAAKNRAGL 900
Query: 1524 GREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVR-----YYRITYGETGG 1578
G E + + S P++L V T ++ ++WD P + R Y + + +
Sbjct: 901 GEEFEKEIRTPEDLPSGFPQNLHVTGLTTSTTELAWDPPVLAERNGRIISYTVVFRDINS 960
Query: 1579 NSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQ 1638
+Q T + + T++GLKP Y I V A T +G P S S E
Sbjct: 961 QQELQNIT---TDTRFTLTGLKPDTTYDIKVRAWTSKGSGPLSPSIQSRTMPVEQVFAKN 1017
Query: 1639 MQVTDVQDNSISVKW-LPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTV 1697
+V S+ + W +P S Y+ K + G ++ I LQP
Sbjct: 1018 FRVAAAMKTSVLLSWEVPDS-----YKSAVPFKILYNGQSVEVDGHSMRKL-IADLQPNT 1071
Query: 1698 EY 1699
EY
Sbjct: 1072 EY 1073
Score = 82.8 bits (203), Expect = 4e-15
Identities = 126/575 (21%), Positives = 224/575 (38%), Gaps = 76/575 (13%)
Query: 628 IQWNAPQPSHISKY-ILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQ 686
+ W P I Y ++ W ++ + K P +SYT++ LKP +Y QL +
Sbjct: 530 LSWLLPPQERIIMYELVYWAAEDEDQQHKVTFDP--TSSYTLEDLKPDTLYRFQLAARSD 587
Query: 687 YGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWV----- 741
G T T+ STP + P ++ S T + VSWV
Sbjct: 588 MGVGVFTPTIEARTAQSTP---------SAPPQKVMCVSMGSTTVR-----VSWVPPPAD 633
Query: 742 SASDTVSGFRVEYELSEEGDEPQYL--DLPSTATSVNIPDLLPGRKYIVNVYQISEDG-- 797
S + ++ + V YE + D +++ + +S ++ L +Y V V ++ G
Sbjct: 634 SRNGVITQYSVAYEAVDGEDRGRHVVDGISREHSSWDLVGLEKWTEYRVWVRAHTDVGPG 693
Query: 798 -EQSLILSTSQTTAPDAPPDPT-VDQVDDTSIVVRW-----SRPQAPITGYRIVYSPSVE 850
E S +L + P PP V+ ++ T++ V W S+ I GY++ Y
Sbjct: 694 PESSPVLVRTDEDVPSGPPRKVEVEPLNSTAVHVYWKLPVPSKQHGQIRGYQVTYVRLEN 753
Query: 851 GSSTELNL------------PETAN--SVTLSDLQPGVQYNITIYAVE---ENQESTPVV 893
G L + PE + T+S L P Y++T+ A + S P +
Sbjct: 754 GEPRGLPIIQDVMLAEAQWRPEESEDYETTISGLTPETTYSVTVAAYTTKGDGARSKPKI 813
Query: 894 IQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIM-WTPPE---SAVTGYRVDVIPVNLPGE 949
+ TTG VP R + T + ++ W PP+ + GYR+ +
Sbjct: 814 V--TTTG-----AVPG-RPTMMISTTAMNTALLQWHPPKELPGELLGYRLQYCRADEARP 865
Query: 950 HGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPT----NLQF 1005
+ F VTGL G TY F++ A + + + T D P+ NL
Sbjct: 866 NTIDFGKDDQHFT-VTGLHKGTTYIFRLAAKNRAGLGEEFEKEIRTPEDLPSGFPQNLHV 924
Query: 1006 VNETDSTVLVRWTPP-RAQITGYRLTVGLTRR---GQPRQYNVGPSVSKYPLRNLQPASE 1061
T ST + W PP A+ G ++ + R Q N+ + +++ L L+P +
Sbjct: 925 TGLTTSTTELAWDPPVLAERNGRIISYTVVFRDINSQQELQNI-TTDTRFTLTGLKPDTT 983
Query: 1062 YTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVT---ETTIVITWTPAPRIGFKLG 1118
Y + + A P + + + P + N V +T+++++W +
Sbjct: 984 YDIKVRAWTSKGSGPLSPSIQSRTMPVEQVFAKNFRVAAAMKTSVLLSWEVPDSYKSAVP 1043
Query: 1119 VRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTI 1153
+ G++ EV S +++ L P EY + +
Sbjct: 1044 FKILYNGQSV-EVDGHSMRKLIADLQPNTEYSFVL 1077
>gi|20665034 tenascin XB isoform 2 [Homo sapiens]
Length = 673
Score = 147 bits (370), Expect = 2e-34
Identities = 109/439 (24%), Positives = 191/439 (43%), Gaps = 30/439 (6%)
Query: 1651 VKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSG 1710
+ W + P + V NG P G DQ+++ I GL+P+ Y +Y +
Sbjct: 3 LSWSVAQGPFDSFVVQYEDTNGQ-PQALLVDG-DQSKILISGLEPSTPYRFLLYGLHEGK 60
Query: 1711 ESQPLVQTAVTNI---------DRPK--GLAFTDVDVDSIKIAWESPQGQVSRYRVTYSS 1759
PL T + RP+ L+ TDV S+++ WE+P G + + +
Sbjct: 61 RLGPLSAEGTTGLAPAGQTSEESRPRLSQLSVTDVTTSSLRLNWEAPPGAFDSFLLRFGV 120
Query: 1760 PEDGIHELFPAP--------DGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQST 1811
P E P P G +A L+ LR G+ Y++++ L ++ + GT T
Sbjct: 121 PSPSTLEPHPRPLLQRELMVPGTRHSAVLRDLRSGTLYSLTLYGLRGPHKADSIQGTART 180
Query: 1812 AIP---APTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSV 1868
P +P DL+F+++ TS W PP + ++V + P + + + + +
Sbjct: 181 LSPVLESPRDLQFSEIRETSAKVNWMPPPSRADSFKVSYQLADGGEP-QSVQVDGQARTQ 239
Query: 1869 VVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTK 1928
+ GL+ +YEV+V +++ S P G +TT+ + P + R + TE + W+
Sbjct: 240 KLQGLIPGARYEVTVVSVRGFEESEPLTGFLTTVPD--GPTQLRALNLTEGFAVLHWKPP 297
Query: 1929 TETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVI 1988
+ + V V A G P+Q Y + L T+Y + L +SP I
Sbjct: 298 QNPVDTYDVQ-VTAPGAPPLQAETPGSAVDYPLHDLVLHTNYTATVRGLRGPNLTSPASI 356
Query: 1989 DASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTE 2048
+T ++AP +L TP + L++W P R GY++ + PG +E++ G+T
Sbjct: 357 TFTTGLEAPRDLEAKEVTPRTALLTWTEPPVRPAGYLLSFHTPGGQNQEIL--LPGGITS 414
Query: 2049 ATITGLEPGTEYTIYVIAL 2067
+ GL P T Y + A+
Sbjct: 415 HQLLGLFPSTSYNARLQAM 433
Score = 129 bits (325), Expect = 3e-29
Identities = 113/471 (23%), Positives = 197/471 (41%), Gaps = 39/471 (8%)
Query: 1374 MRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVY 1433
MR++W+ +F+V+Y + L + + ++++ L P T Y + ++
Sbjct: 1 MRLSWSVAQG-PFDSFVVQYEDTNGQPQA--LLVDGDQSKILISGLEPSTPYRFLLYGLH 57
Query: 1434 EQHESTPLRGRQKTGLDSPTG------------IDFSDITANSFTVHWIAPRATITGYRI 1481
E PL TGL +P G + +D+T +S ++W AP + +
Sbjct: 58 EGKRLGPLSAEGTTGL-APAGQTSEESRPRLSQLSVTDVTTSSLRLNWEAPPGAFDSFLL 116
Query: 1482 RH---HPEHFSGRP-----REDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIG 1533
R P P RE VP +R+S L +L GT Y +++ L G ++ + G
Sbjct: 117 RFGVPSPSTLEPHPRPLLQRELMVPGTRHSAVLRDLRSGTLYSLTLYGLRGPHKADSIQG 176
Query: 1534 QQSTVSDV---PRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGS 1590
T+S V PRDL+ TS ++W P ++++Y G P Q V G
Sbjct: 177 TARTLSPVLESPRDLQFSEIRETSAKVNWMPPPSRADSFKVSYQLADGGEP-QSVQVDGQ 235
Query: 1591 KSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSIS 1650
T + GL PG Y +TV +V G + S+P++ T D P+Q++ ++ +
Sbjct: 236 ARTQKLQGLIPGARYEVTVVSVRGFEE----SEPLTGFLTTVPDGPTQLRALNLTEGFAV 291
Query: 1651 VKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSG 1710
+ W P +PV Y V T P P + +T G + + L Y +V
Sbjct: 292 LHWKPPQNPVDTYDVQVTAPGAP-PLQAETPG-SAVDYPLHDLVLHTNYTATVRGLRGPN 349
Query: 1711 ESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPA 1770
+ P T T ++ P+ L +V + + W P + + Y +++ +P E+
Sbjct: 350 LTSPASITFTTGLEAPRDLEAKEVTPRTALLTWTEPPVRPAGYLLSFHTPGGQNQEIL-- 407
Query: 1771 PDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTA---IPAPTD 1818
G + +L GL P + Y + A+ P+ + +T IP P D
Sbjct: 408 LPGGITSHQLLGLFPSTSYNARLQAMWGQSLLPPVSTSFTTGGLRIPFPRD 458
Score = 119 bits (297), Expect = 5e-26
Identities = 108/455 (23%), Positives = 184/455 (40%), Gaps = 28/455 (6%)
Query: 1557 ISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAV-TGR 1615
+SW + + Y +T G Q V G +S ISGL+P Y +Y + G+
Sbjct: 3 LSWSVAQGPFDSFVVQYEDTNGQP--QALLVDGDQSKILISGLEPSTPYRFLLYGLHEGK 60
Query: 1616 GDSPASSKPIS----INYRTEIDKP--SQMQVTDVQDNSISVKWLPSSSPVTGYRV---- 1665
P S++ + +E +P SQ+ VTDV +S+ + W + +
Sbjct: 61 RLGPLSAEGTTGLAPAGQTSEESRPRLSQLSVTDVTTSSLRLNWEAPPGAFDSFLLRFGV 120
Query: 1666 ----TTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVT 1721
T P P + + + L+ Y +++Y ++ + TA T
Sbjct: 121 PSPSTLEPHPRPLLQRELMVPGTRHSAVLRDLRSGTLYSLTLYGLRGPHKADSIQGTART 180
Query: 1722 ---NIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTA 1778
++ P+ L F+++ S K+ W P + ++V+Y + G + DG+ T
Sbjct: 181 LSPVLESPRDLQFSEIRETSAKVNWMPPPSRADSFKVSYQLADGGEPQSVQV-DGQARTQ 239
Query: 1779 ELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNV 1838
+LQGL PG+ Y V+VV++ ES+PL G +T PT L+ +T W PP
Sbjct: 240 KLQGLIPGARYEVTVVSVRGFEESEPLTGFLTTVPDGPTQLRALNLTEGFAVLHWKPPQN 299
Query: 1839 QLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGV 1898
+ Y V+VT P + + + L++ T Y +V L+ + PA
Sbjct: 300 PVDTYDVQVT--APGAPPLQAETPGSAVDYPLHDLVLHTNYTATVRGLRGPNLTSPASIT 357
Query: 1899 VTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKP-DVR 1957
TT + PR + T T ++W G+ + GQ Q + P +
Sbjct: 358 FTT--GLEAPRDLEAKEVTPRTALLTWTEPPVRPAGYLLSFHTPGGQN--QEILLPGGIT 413
Query: 1958 SYTITGLQPGTDYKIYLYTLNDNARSSPVVIDAST 1992
S+ + GL P T Y L + + PV +T
Sbjct: 414 SHQLLGLFPSTSYNARLQAMWGQSLLPPVSTSFTT 448
Score = 117 bits (294), Expect = 1e-25
Identities = 115/480 (23%), Positives = 197/480 (41%), Gaps = 57/480 (11%)
Query: 628 IQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQY 687
+ W+ Q +++++ N G+ + + G + I GL+P Y L Y
Sbjct: 3 LSWSVAQ-GPFDSFVVQYEDTN--GQPQALLVDGDQSKILISGLEPSTPYRFLL-----Y 54
Query: 688 GHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTV 747
G E R + +T + G+T+ S + SVT++T SS ++W +
Sbjct: 55 GLHEGKRLGPLSAEGTTGLAP---AGQTSEESRPRLSQLSVTDVTTSSLRLNWEAPPGAF 111
Query: 748 SGFRVEYELSEEGD-EP-------QYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQ 799
F + + + EP + L +P T S + DL G Y + +Y + +
Sbjct: 112 DSFLLRFGVPSPSTLEPHPRPLLQRELMVPGTRHSAVLRDLRSGTLYSLTLYGLRGPHKA 171
Query: 800 SLILSTSQTTAP--DAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELN 857
I T++T +P ++P D ++ +TS V W P + +++ Y + G +
Sbjct: 172 DSIQGTARTLSPVLESPRDLQFSEIRETSAKVNWMPPPSRADSFKVSYQLADGGEPQSVQ 231
Query: 858 LPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVP-SPRDLQFV 916
+ A + L L PG +Y +T+ +V +ES P+ T TVP P L+ +
Sbjct: 232 VDGQARTQKLQGLIPGARYEVTVVSVRGFEESEPL--------TGFLTTVPDGPTQLRAL 283
Query: 917 EVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQR-----------LPISRNTFAEVT 965
+T+ + W PP++ V Y V V P + L + N A V
Sbjct: 284 NLTEGFAVLHWKPPQNPVDTYDVQVTAPGAPPLQAETPGSAVDYPLHDLVLHTNYTATVR 343
Query: 966 GL-SPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQI 1024
GL P +T P + TT L+AP +L+ T T L+ WT P +
Sbjct: 344 GLRGPNLT--------------SPASITFTTGLEAPRDLEAKEVTPRTALLTWTEPPVRP 389
Query: 1025 TGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTT 1084
GY L+ T GQ ++ + ++ + L L P++ Y L A+ G P + FTT
Sbjct: 390 AGYLLSFH-TPGGQNQEILLPGGITSHQLLGLFPSTSYNARLQAMWGQSLLPPVSTSFTT 448
Score = 115 bits (287), Expect = 7e-25
Identities = 99/406 (24%), Positives = 167/406 (41%), Gaps = 32/406 (7%)
Query: 1316 VDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAVPPP-----------TDL 1364
VD ++GLEP Y + L G P + T + P + L
Sbjct: 31 VDGDQSKILISGLEPSTPYRFLLYGLHEGKRLGPLSAEGTTGLAPAGQTSEESRPRLSQL 90
Query: 1365 RFTNIGPDTMRVTWAPPPSIDLTNFLVRY---SPVKNEEDVA-----ELSISPSDNAVVL 1416
T++ ++R+ W PP +FL+R+ SP E EL + + ++ VL
Sbjct: 91 SVTDVTTSSLRLNWEAPPGA-FDSFLLRFGVPSPSTLEPHPRPLLQRELMVPGTRHSAVL 149
Query: 1417 TNLLPGTEYVVSVSSVYEQHESTPLRGRQKT---GLDSPTGIDFSDITANSFTVHWIAPR 1473
+L GT Y +++ + H++ ++G +T L+SP + FS+I S V+W+ P
Sbjct: 150 RDLRSGTLYSLTLYGLRGPHKADSIQGTARTLSPVLESPRDLQFSEIRETSAKVNWMPPP 209
Query: 1474 ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIG 1533
+ +++ + G P+ +V + L L PG Y V++V++ G EES L G
Sbjct: 210 SRADSFKVSYQLAD-GGEPQSVQVDGQARTQKLQGLIPGARYEVTVVSVRGFEESEPLTG 268
Query: 1534 QQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKST 1593
+TV D P L + T ++ W P V Y + T +P + PGS
Sbjct: 269 FLTTVPDGPTQLRALNLTEGFAVLHWKPPQNPVDTYDVQV--TAPGAPPLQAETPGSAVD 326
Query: 1594 ATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKW 1653
+ L +YT TV + G P + P SI + T ++ P ++ +V + + W
Sbjct: 327 YPLHDLVLHTNYTATVRGLRG----PNLTSPASITFTTGLEAPRDLEAKEVTPRTALLTW 382
Query: 1654 LPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEY 1699
GY ++ G G T + GL P+ Y
Sbjct: 383 TEPPVRPAGYLLSFHTPGGQNQEILLPGG--ITSHQLLGLFPSTSY 426
Score = 106 bits (265), Expect = 2e-22
Identities = 109/483 (22%), Positives = 179/483 (37%), Gaps = 60/483 (12%)
Query: 1739 IKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHD 1798
++++W QG + V Y L DG++ + GL P + Y + LH+
Sbjct: 1 MRLSWSVAQGPFDSFVVQYEDTNGQPQALLV--DGDQSKILISGLEPSTPYRFLLYGLHE 58
Query: 1799 DMESQPLIGTQSTAI-----------PAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVR- 1846
PL +T + P + L T VT +SL W P + +R
Sbjct: 59 GKRLGPLSAEGTTGLAPAGQTSEESRPRLSQLSVTDVTTSSLRLNWEAPPGAFDSFLLRF 118
Query: 1847 -------VTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVV 1899
+ P + +E+ + S V+ L T Y +++Y L+ + QG
Sbjct: 119 GVPSPSTLEPHPRPLLQRELMVPGTRHSAVLRDLRSGTLYSLTLYGLRGPHKADSIQGTA 178
Query: 1900 TTLENV-SPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRS 1958
TL V PR + ++ ET+ ++W F+V A+G P + R+
Sbjct: 179 RTLSPVLESPRDLQFSEIRETSAKVNWMPPPSRADSFKVSYQLADGGEPQSVQVDGQART 238
Query: 1959 YTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPR 2018
+ GL PG Y++ + ++ S P+ +T D P+ LR L T ++ W+PP+
Sbjct: 239 QKLQGLIPGARYEVTVVSVRGFEESEPLTGFLTTVPDGPTQLRALNLTEGFAVLHWKPPQ 298
Query: 2019 ARITGYIIKYEKPGSPPREVVPRPRPG-VTEATITGLEPGTEYTIYVIALKNNQKSEPLI 2077
+ Y ++ PG+PP + PG + + L T YT V L+ + P
Sbjct: 299 NPVDTYDVQVTAPGAPPLQA---ETPGSAVDYPLHDLVLHTNYTATVRGLRGPNLTSPAS 355
Query: 2078 GRKKTDELPQLVTLPHPNLHGPEILDVPSTVQKTPFVT---------------HPGYDTG 2122
T L P L+ +T +T H
Sbjct: 356 ITFTT------------GLEAPRDLEAKEVTPRTALLTWTEPPVRPAGYLLSFHTPGGQN 403
Query: 2123 NGIQLPG--TS----GQQPSVGQQMIFEEHGFRRTTPPTTATPIRHRPR-PYPPNVGEEI 2175
I LPG TS G PS + + PP + + R P+P + GEE+
Sbjct: 404 QEILLPGGITSHQLLGLFPSTSYNARLQAMWGQSLLPPVSTSFTTGGLRIPFPRDCGEEM 463
Query: 2176 QIG 2178
Q G
Sbjct: 464 QNG 466
Score = 95.9 bits (237), Expect = 4e-19
Identities = 105/452 (23%), Positives = 183/452 (40%), Gaps = 35/452 (7%)
Query: 831 WSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQEST 890
WS Q P + + Y + G L + + + +S L+P Y +Y + E +
Sbjct: 5 WSVAQGPFDSFVVQYEDT-NGQPQALLVDGDQSKILISGLEPSTPYRFLLYGLHEGKRLG 63
Query: 891 PVVIQQETTGTPRSDTVPSPR----DLQFVEVTDVKVTIMWTPPESAVTGY--RVDVIPV 944
P+ + T P T R L +VT + + W P A + R V
Sbjct: 64 PLSAEGTTGLAPAGQTSEESRPRLSQLSVTDVTTSSLRLNWEAPPGAFDSFLLRFGVPSP 123
Query: 945 NLPGEHGQRL-------PISRNTFAEVTGLSPGVTYYFKVFAVS--HGRESKPLTAQQTT 995
+ H + L P +R++ A + L G Y ++ + H +S TA+ +
Sbjct: 124 STLEPHPRPLLQRELMVPGTRHS-AVLRDLRSGTLYSLTLYGLRGPHKADSIQGTARTLS 182
Query: 996 K-LDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLR 1054
L++P +LQF +++ V W PP ++ ++++ L G+P+ V L+
Sbjct: 183 PVLESPRDLQFSEIRETSAKVNWMPPPSRADSFKVSYQLADGGEPQSVQVDGQARTQKLQ 242
Query: 1055 NLQPASEYTVSLVAIKGNQESPKATGVFTTLQPG-SSIPPYNTEVTETTIVITWTPAPRI 1113
L P + Y V++V+++G +ES TG TT+ G + + N +TE V+ W P
Sbjct: 243 GLIPGARYEVTVVSVRGFEESEPLTGFLTTVPDGPTQLRALN--LTEGFAVLHWKPPQNP 300
Query: 1114 GFKLGVRPSQGGEAPREVTSDSGSI--VVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVV 1171
V+ + G P + + ++ + L Y T++ LR G +P
Sbjct: 301 VDTYDVQVTAPGAPPLQAETPGSAVDYPLHDLVLHTNYTATVRGLR-GPNLTSPASITFT 359
Query: 1172 TPLSPPTNLHL-EANPDTGVLTVSWERSTTPDI--TGYRITTTPTNGQQGNSLEEVVHAD 1228
T L P +L E P T +LT W T P + GY ++ GQ + E ++
Sbjct: 360 TGLEAPRDLEAKEVTPRTALLT--W---TEPPVRPAGYLLSFHTPGGQ---NQEILLPGG 411
Query: 1229 QSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS 1260
+S L P YN + + P+S
Sbjct: 412 ITSHQLLGLFPSTSYNARLQAMWGQSLLPPVS 443
Score = 75.1 bits (183), Expect = 8e-13
Identities = 101/440 (22%), Positives = 172/440 (39%), Gaps = 42/440 (9%)
Query: 1037 GQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAI-KGNQESPKATGVFTTLQPGSSIPPYN 1095
GQP+ V SK + L+P++ Y L + +G + P + T L P +
Sbjct: 24 GQPQALLVDGDQSKILISGLEPSTPYRFLLYGLHEGKRLGPLSAEGTTGLAPAGQTSEES 83
Query: 1096 ---------TEVTETTIVITWTPAP----RIGFKLGV-RPSQGGEAPRE-------VTSD 1134
T+VT +++ + W P + GV PS PR V
Sbjct: 84 RPRLSQLSVTDVTTSSLRLNWEAPPGAFDSFLLRFGVPSPSTLEPHPRPLLQRELMVPGT 143
Query: 1135 SGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSP----PTNLHLEANPDTGV 1190
S V+ L G Y T+ LR + D+ + LSP P +L +T
Sbjct: 144 RHSAVLRDLRSGTLYSLTLYGLRGPHKADS--IQGTARTLSPVLESPRDLQFSEIRETSA 201
Query: 1191 LTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTV 1250
V+W + ++++ +G + S++ V + L PG Y V+V +V
Sbjct: 202 -KVNWMPPPSR-ADSFKVSYQLADGGEPQSVQ--VDGQARTQKLQGLIPGARYEVTVVSV 257
Query: 1251 KDDKESVPISD--TIIPEVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGEG 1308
+ +ES P++ T +P+ P T L +++T+ L W P + + Y + V A G
Sbjct: 258 RGFEESEPLTGFLTTVPDGP--TQLRALNLTEGFAVLHWKP-PQNPVDTYDVQVTAPGA- 313
Query: 1309 IPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAVPPPTDLRFTN 1368
P + S Y + L +Y +V L ++P ++T T + P DL
Sbjct: 314 -PPLQAETPGSAVDYPLHDLVLHTNYTATVRGLRGPNLTSPASITFTTGLEAPRDLEAKE 372
Query: 1369 IGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVS 1428
+ P T +TW PP L ++P + E+ + + L L P T Y
Sbjct: 373 VTPRTALLTWTEPPVRPAGYLLSFHTPGGQNQ---EILLPGGITSHQLLGLFPSTSYNAR 429
Query: 1429 VSSVYEQHESTPLRGRQKTG 1448
+ +++ Q P+ TG
Sbjct: 430 LQAMWGQSLLPPVSTSFTTG 449
>gi|189217853 matrix metalloproteinase 2 isoform b [Homo sapiens]
Length = 610
Score = 146 bits (368), Expect = 3e-34
Identities = 70/178 (39%), Positives = 97/178 (54%), Gaps = 16/178 (8%)
Query: 344 ETAVTQTYGGNSNGEPCVLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTD 403
E V + GN++GE C PF +NG+ + SCT GR DG LWCSTT N+E+D KY FC
Sbjct: 167 EGQVVRVKYGNADGEYCKFPFLFNGKEYNSCTDTGRSDGFLWCSTTYNFEKDGKYGFCPH 226
Query: 404 HTVLVQTRGGNSNGALCHFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPM 463
+ T GGN+ G C FPF + +Y CT+EGR D +WCGTT++YD D+K+GFCP
Sbjct: 227 EALF--TMGGNAEGQPCKFPFRFQGTSYDSCTTEGRTDGYRWCGTTEDYDRDKKYGFCPE 284
Query: 464 AAHEEICTTNEGV-----MYRIGDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRD 516
A + +EG +G++++ CT G G+ C + D
Sbjct: 285 TAMSTVGGNSEGAPCVFPFTFLGNKYES---------CTSAGRSDGKMWCATTANYDD 333
Score = 145 bits (365), Expect = 6e-34
Identities = 77/171 (45%), Positives = 97/171 (56%), Gaps = 18/171 (10%)
Query: 305 YGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPCVLPF 364
Y C TD+G S G W T N + G C A+ T GGN+ G+PC PF
Sbjct: 194 YNSC-TDTG--RSDGFLWCSTTYNFEKD----GKYGFCPHEALF-TMGGNAEGQPCKFPF 245
Query: 365 TYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALCHFPF 424
+ G ++ SCTTEGR DG+ WC TT +Y++D+KY FC + + T GGNS GA C FPF
Sbjct: 246 RFQGTSYDSCTTEGRTDGYRWCGTTEDYDRDKKYGFCPE--TAMSTVGGNSEGAPCVFPF 303
Query: 425 LYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCP--------MAAHE 467
+ + Y CTS GR D WC TT NYD D+K+GFCP +AAHE
Sbjct: 304 TFLGNKYESCTSAGRSDGKMWCATTANYDDDRKWGFCPDQGYSLFLVAAHE 354
>gi|11342666 matrix metalloproteinase 2 isoform a preproprotein
[Homo sapiens]
Length = 660
Score = 146 bits (368), Expect = 3e-34
Identities = 70/178 (39%), Positives = 97/178 (54%), Gaps = 16/178 (8%)
Query: 344 ETAVTQTYGGNSNGEPCVLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTD 403
E V + GN++GE C PF +NG+ + SCT GR DG LWCSTT N+E+D KY FC
Sbjct: 217 EGQVVRVKYGNADGEYCKFPFLFNGKEYNSCTDTGRSDGFLWCSTTYNFEKDGKYGFCPH 276
Query: 404 HTVLVQTRGGNSNGALCHFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPM 463
+ T GGN+ G C FPF + +Y CT+EGR D +WCGTT++YD D+K+GFCP
Sbjct: 277 EALF--TMGGNAEGQPCKFPFRFQGTSYDSCTTEGRTDGYRWCGTTEDYDRDKKYGFCPE 334
Query: 464 AAHEEICTTNEGV-----MYRIGDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRD 516
A + +EG +G++++ CT G G+ C + D
Sbjct: 335 TAMSTVGGNSEGAPCVFPFTFLGNKYES---------CTSAGRSDGKMWCATTANYDD 383
Score = 145 bits (365), Expect = 6e-34
Identities = 77/171 (45%), Positives = 97/171 (56%), Gaps = 18/171 (10%)
Query: 305 YGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPCVLPF 364
Y C TD+G S G W T N + G C A+ T GGN+ G+PC PF
Sbjct: 244 YNSC-TDTG--RSDGFLWCSTTYNFEKD----GKYGFCPHEALF-TMGGNAEGQPCKFPF 295
Query: 365 TYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALCHFPF 424
+ G ++ SCTTEGR DG+ WC TT +Y++D+KY FC + + T GGNS GA C FPF
Sbjct: 296 RFQGTSYDSCTTEGRTDGYRWCGTTEDYDRDKKYGFCPE--TAMSTVGGNSEGAPCVFPF 353
Query: 425 LYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCP--------MAAHE 467
+ + Y CTS GR D WC TT NYD D+K+GFCP +AAHE
Sbjct: 354 TFLGNKYESCTSAGRSDGKMWCATTANYDDDRKWGFCPDQGYSLFLVAAHE 404
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.132 0.408
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 113,007,643
Number of Sequences: 37866
Number of extensions: 6035983
Number of successful extensions: 24699
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 97
Number of HSP's successfully gapped in prelim test: 218
Number of HSP's that attempted gapping in prelim test: 12104
Number of HSP's gapped (non-prelim): 3669
length of query: 2477
length of database: 18,247,518
effective HSP length: 119
effective length of query: 2358
effective length of database: 13,741,464
effective search space: 32402372112
effective search space used: 32402372112
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 71 (32.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.