Guide to the Human Genome
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Search of human proteins with 47132555

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|47132555 fibronectin 1 isoform 4 preproprotein [Homo
sapiens]
         (2330 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|47132555 fibronectin 1 isoform 4 preproprotein [Homo sapiens]     4852   0.0  
gi|16933542 fibronectin 1 isoform 3 preproprotein [Homo sapiens]     4838   0.0  
gi|47132553 fibronectin 1 isoform 5 preproprotein [Homo sapiens]     4100   0.0  
gi|47132549 fibronectin 1 isoform 6 preproprotein [Homo sapiens]     3543   0.0  
gi|47132557 fibronectin 1 isoform 1 preproprotein [Homo sapiens]     3008   0.0  
gi|47132551 fibronectin 1 isoform 2 preproprotein [Homo sapiens]     3008   0.0  
gi|47132547 fibronectin 1 isoform 7 preproprotein [Homo sapiens]     1440   0.0  
gi|93141047 collagen, type XII, alpha 1 long isoform precursor [...   383   e-105
gi|153946395 tenascin C precursor [Homo sapiens]                      360   7e-99
gi|157384973 tenascin R [Homo sapiens]                                353   1e-96
gi|62988324 tenascin N [Homo sapiens]                                 315   3e-85
gi|188528648 tenascin XB isoform 1 precursor [Homo sapiens]           313   2e-84
gi|93141049 collagen, type XII, alpha 1 short isoform precursor ...   296   2e-79
gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]         235   4e-61
gi|55743096 collagen, type XIV, alpha 1 [Homo sapiens]                209   3e-53
gi|222352127 sidekick 2 [Homo sapiens]                                164   7e-40
gi|157952215 protein tyrosine phosphatase, receptor type, B isof...   164   1e-39
gi|157952213 protein tyrosine phosphatase, receptor type, B isof...   164   1e-39
gi|112734845 collagen, type XX, alpha 1 [Homo sapiens]                155   4e-37
gi|110349719 titin isoform N2-A [Homo sapiens]                        154   1e-36
gi|110349717 titin isoform novex-2 [Homo sapiens]                     154   1e-36
gi|110349713 titin isoform novex-1 [Homo sapiens]                     154   1e-36
gi|110349715 titin isoform N2-B [Homo sapiens]                        154   1e-36
gi|109633039 protein tyrosine phosphatase, receptor type, F isof...   153   2e-36
gi|119220552 sidekick 1 [Homo sapiens]                                152   5e-36
gi|18860892 protein tyrosine phosphatase, receptor type, D isofo...   149   2e-35
gi|20665034 tenascin XB isoform 2 [Homo sapiens]                      148   7e-35
gi|109633041 protein tyrosine phosphatase, receptor type, F isof...   147   1e-34
gi|189217853 matrix metalloproteinase 2 isoform b [Homo sapiens]      146   3e-34
gi|11342666 matrix metalloproteinase 2 isoform a preproprotein [...   146   3e-34

>gi|47132555 fibronectin 1 isoform 4 preproprotein [Homo sapiens]
          Length = 2330

 Score = 4852 bits (12585), Expect = 0.0
 Identities = 2330/2330 (100%), Positives = 2330/2330 (100%)

Query: 1    MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ 60
            MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ
Sbjct: 1    MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ 60

Query: 61   INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI 120
            INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI
Sbjct: 61   INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI 120

Query: 121  WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK 180
            WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK
Sbjct: 121  WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK 180

Query: 181  PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY 240
            PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY
Sbjct: 181  PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY 240

Query: 241  RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP 300
            RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP
Sbjct: 241  RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP 300

Query: 301  QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC 360
            QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC
Sbjct: 301  QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC 360

Query: 361  VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC 420
            VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC
Sbjct: 361  VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC 420

Query: 421  HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI 480
            HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI
Sbjct: 421  HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI 480

Query: 481  GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM 540
            GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM
Sbjct: 481  GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM 540

Query: 541  LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ 600
            LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ
Sbjct: 541  LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ 600

Query: 601  PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP 660
            PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP
Sbjct: 601  PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP 660

Query: 661  GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP 720
            GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP
Sbjct: 661  GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP 720

Query: 721  LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL 780
            LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL
Sbjct: 721  LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL 780

Query: 781  LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITG 840
            LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITG
Sbjct: 781  LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITG 840

Query: 841  YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG 900
            YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG
Sbjct: 841  YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG 900

Query: 901  TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT 960
            TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT
Sbjct: 901  TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT 960

Query: 961  FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP 1020
            FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP
Sbjct: 961  FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP 1020

Query: 1021 RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG 1080
            RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG
Sbjct: 1021 RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG 1080

Query: 1081 VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV 1140
            VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV
Sbjct: 1081 VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV 1140

Query: 1141 SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT 1200
            SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT
Sbjct: 1141 SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT 1200

Query: 1201 PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS 1260
            PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS
Sbjct: 1201 PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS 1260

Query: 1261 DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSD 1320
            DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSD
Sbjct: 1261 DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSD 1320

Query: 1321 NAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIA 1380
            NAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIA
Sbjct: 1321 NAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIA 1380

Query: 1381 PRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLL 1440
            PRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLL
Sbjct: 1381 PRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLL 1440

Query: 1441 IGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSK 1500
            IGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSK
Sbjct: 1441 IGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSK 1500

Query: 1501 STATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISV 1560
            STATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISV
Sbjct: 1501 STATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISV 1560

Query: 1561 KWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE 1620
            KWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE
Sbjct: 1561 KWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE 1620

Query: 1621 SQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAP 1680
            SQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAP
Sbjct: 1621 SQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAP 1680

Query: 1681 DGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSA 1740
            DGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSA
Sbjct: 1681 DGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSA 1740

Query: 1741 QWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLT 1800
            QWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLT
Sbjct: 1741 QWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLT 1800

Query: 1801 SRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRT 1860
            SRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRT
Sbjct: 1801 SRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRT 1860

Query: 1861 IKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLL 1920
            IKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLL
Sbjct: 1861 IKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLL 1920

Query: 1921 VSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQ 1980
            VSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQ
Sbjct: 1921 VSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQ 1980

Query: 1981 KSEPLIGRKKTVQKTPFVTHPGYDTGNGIQLPGTSGQQPSVGQQMIFEEHGFRRTTPPTT 2040
            KSEPLIGRKKTVQKTPFVTHPGYDTGNGIQLPGTSGQQPSVGQQMIFEEHGFRRTTPPTT
Sbjct: 1981 KSEPLIGRKKTVQKTPFVTHPGYDTGNGIQLPGTSGQQPSVGQQMIFEEHGFRRTTPPTT 2040

Query: 2041 ATPIRHRPRPYPPNVGQEALSQTTISWAPFQDTSEYIISCHPVGTDEEPLQFRVPGTSTS 2100
            ATPIRHRPRPYPPNVGQEALSQTTISWAPFQDTSEYIISCHPVGTDEEPLQFRVPGTSTS
Sbjct: 2041 ATPIRHRPRPYPPNVGQEALSQTTISWAPFQDTSEYIISCHPVGTDEEPLQFRVPGTSTS 2100

Query: 2101 ATLTGLTRGATYNIIVEALKDQQRHKVREEVVTVGNSVNEGLNQPTDDSCFDPYTVSHYA 2160
            ATLTGLTRGATYNIIVEALKDQQRHKVREEVVTVGNSVNEGLNQPTDDSCFDPYTVSHYA
Sbjct: 2101 ATLTGLTRGATYNIIVEALKDQQRHKVREEVVTVGNSVNEGLNQPTDDSCFDPYTVSHYA 2160

Query: 2161 VGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHDNGVNYKIGEKWDRQGENGQMMSC 2220
            VGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHDNGVNYKIGEKWDRQGENGQMMSC
Sbjct: 2161 VGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHDNGVNYKIGEKWDRQGENGQMMSC 2220

Query: 2221 TCLGNGKGEFKCDPHEATCYDDGKTYHVGEQWQKEYLGAICSCTCFGGQRGWRCDNCRRP 2280
            TCLGNGKGEFKCDPHEATCYDDGKTYHVGEQWQKEYLGAICSCTCFGGQRGWRCDNCRRP
Sbjct: 2221 TCLGNGKGEFKCDPHEATCYDDGKTYHVGEQWQKEYLGAICSCTCFGGQRGWRCDNCRRP 2280

Query: 2281 GGEPSPEGTTGQSYNQYSQRYHQRTNTNVNCPIECFMPLDVQADREDSRE 2330
            GGEPSPEGTTGQSYNQYSQRYHQRTNTNVNCPIECFMPLDVQADREDSRE
Sbjct: 2281 GGEPSPEGTTGQSYNQYSQRYHQRTNTNVNCPIECFMPLDVQADREDSRE 2330


>gi|16933542 fibronectin 1 isoform 3 preproprotein [Homo sapiens]
          Length = 2355

 Score = 4838 bits (12549), Expect = 0.0
 Identities = 2330/2355 (98%), Positives = 2330/2355 (98%), Gaps = 25/2355 (1%)

Query: 1    MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ 60
            MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ
Sbjct: 1    MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ 60

Query: 61   INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI 120
            INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI
Sbjct: 61   INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI 120

Query: 121  WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK 180
            WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK
Sbjct: 121  WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK 180

Query: 181  PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY 240
            PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY
Sbjct: 181  PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY 240

Query: 241  RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP 300
            RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP
Sbjct: 241  RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP 300

Query: 301  QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC 360
            QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC
Sbjct: 301  QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC 360

Query: 361  VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC 420
            VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC
Sbjct: 361  VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC 420

Query: 421  HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI 480
            HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI
Sbjct: 421  HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI 480

Query: 481  GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM 540
            GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM
Sbjct: 481  GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM 540

Query: 541  LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ 600
            LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ
Sbjct: 541  LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ 600

Query: 601  PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP 660
            PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP
Sbjct: 601  PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP 660

Query: 661  GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP 720
            GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP
Sbjct: 661  GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP 720

Query: 721  LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL 780
            LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL
Sbjct: 721  LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL 780

Query: 781  LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITG 840
            LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITG
Sbjct: 781  LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITG 840

Query: 841  YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG 900
            YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG
Sbjct: 841  YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG 900

Query: 901  TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT 960
            TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT
Sbjct: 901  TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT 960

Query: 961  FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP 1020
            FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP
Sbjct: 961  FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP 1020

Query: 1021 RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG 1080
            RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG
Sbjct: 1021 RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG 1080

Query: 1081 VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV 1140
            VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV
Sbjct: 1081 VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV 1140

Query: 1141 SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT 1200
            SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT
Sbjct: 1141 SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT 1200

Query: 1201 PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS 1260
            PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS
Sbjct: 1201 PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS 1260

Query: 1261 DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSD 1320
            DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSD
Sbjct: 1261 DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSD 1320

Query: 1321 NAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIA 1380
            NAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIA
Sbjct: 1321 NAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIA 1380

Query: 1381 PRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLL 1440
            PRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLL
Sbjct: 1381 PRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLL 1440

Query: 1441 IGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSK 1500
            IGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSK
Sbjct: 1441 IGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSK 1500

Query: 1501 STATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISV 1560
            STATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISV
Sbjct: 1501 STATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISV 1560

Query: 1561 KWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE 1620
            KWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE
Sbjct: 1561 KWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE 1620

Query: 1621 SQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAP 1680
            SQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAP
Sbjct: 1621 SQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAP 1680

Query: 1681 DGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSA 1740
            DGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSA
Sbjct: 1681 DGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSA 1740

Query: 1741 QWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLT 1800
            QWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLT
Sbjct: 1741 QWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLT 1800

Query: 1801 SRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRT 1860
            SRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRT
Sbjct: 1801 SRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRT 1860

Query: 1861 IKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLL 1920
            IKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLL
Sbjct: 1861 IKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLL 1920

Query: 1921 VSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQ 1980
            VSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQ
Sbjct: 1921 VSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQ 1980

Query: 1981 KSEPLIGRKK-------------------------TVQKTPFVTHPGYDTGNGIQLPGTS 2015
            KSEPLIGRKK                         TVQKTPFVTHPGYDTGNGIQLPGTS
Sbjct: 1981 KSEPLIGRKKTDELPQLVTLPHPNLHGPEILDVPSTVQKTPFVTHPGYDTGNGIQLPGTS 2040

Query: 2016 GQQPSVGQQMIFEEHGFRRTTPPTTATPIRHRPRPYPPNVGQEALSQTTISWAPFQDTSE 2075
            GQQPSVGQQMIFEEHGFRRTTPPTTATPIRHRPRPYPPNVGQEALSQTTISWAPFQDTSE
Sbjct: 2041 GQQPSVGQQMIFEEHGFRRTTPPTTATPIRHRPRPYPPNVGQEALSQTTISWAPFQDTSE 2100

Query: 2076 YIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHKVREEVVTVG 2135
            YIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHKVREEVVTVG
Sbjct: 2101 YIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHKVREEVVTVG 2160

Query: 2136 NSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWC 2195
            NSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWC
Sbjct: 2161 NSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWC 2220

Query: 2196 HDNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEATCYDDGKTYHVGEQWQKE 2255
            HDNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEATCYDDGKTYHVGEQWQKE
Sbjct: 2221 HDNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEATCYDDGKTYHVGEQWQKE 2280

Query: 2256 YLGAICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYSQRYHQRTNTNVNCPIEC 2315
            YLGAICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYSQRYHQRTNTNVNCPIEC
Sbjct: 2281 YLGAICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYSQRYHQRTNTNVNCPIEC 2340

Query: 2316 FMPLDVQADREDSRE 2330
            FMPLDVQADREDSRE
Sbjct: 2341 FMPLDVQADREDSRE 2355


>gi|47132553 fibronectin 1 isoform 5 preproprotein [Homo sapiens]
          Length = 2296

 Score = 4100 bits (10632), Expect = 0.0
 Identities = 2013/2341 (85%), Positives = 2076/2341 (88%), Gaps = 56/2341 (2%)

Query: 1    MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ 60
            MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ
Sbjct: 1    MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ 60

Query: 61   INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI 120
            INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI
Sbjct: 61   INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI 120

Query: 121  WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK 180
            WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK
Sbjct: 121  WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK 180

Query: 181  PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY 240
            PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY
Sbjct: 181  PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY 240

Query: 241  RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP 300
            RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP
Sbjct: 241  RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP 300

Query: 301  QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC 360
            QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC
Sbjct: 301  QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC 360

Query: 361  VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC 420
            VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC
Sbjct: 361  VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC 420

Query: 421  HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI 480
            HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI
Sbjct: 421  HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI 480

Query: 481  GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM 540
            GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM
Sbjct: 481  GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM 540

Query: 541  LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ 600
            LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ
Sbjct: 541  LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ 600

Query: 601  PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP 660
            PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP
Sbjct: 601  PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP 660

Query: 661  GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP 720
            GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP
Sbjct: 661  GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP 720

Query: 721  LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL 780
            LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL
Sbjct: 721  LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL 780

Query: 781  LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITG 840
            LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITG
Sbjct: 781  LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITG 840

Query: 841  YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG 900
            YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG
Sbjct: 841  YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG 900

Query: 901  TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT 960
            TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT
Sbjct: 901  TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT 960

Query: 961  FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP 1020
            FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP
Sbjct: 961  FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP 1020

Query: 1021 RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG 1080
            RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG
Sbjct: 1021 RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG 1080

Query: 1081 VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV 1140
            VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV
Sbjct: 1081 VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV 1140

Query: 1141 SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT 1200
            SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT
Sbjct: 1141 SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT 1200

Query: 1201 PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS 1260
            PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS
Sbjct: 1201 PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS 1260

Query: 1261 DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSD 1320
            DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSD
Sbjct: 1261 DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSD 1320

Query: 1321 NAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIA 1380
            NAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIA
Sbjct: 1321 NAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIA 1380

Query: 1381 PRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLL 1440
            PRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLL
Sbjct: 1381 PRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLL 1440

Query: 1441 IGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSK 1500
            IGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSK
Sbjct: 1441 IGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSK 1500

Query: 1501 STATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISV 1560
            STATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISV
Sbjct: 1501 STATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISV 1560

Query: 1561 KWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE 1620
            KWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE
Sbjct: 1561 KWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE 1620

Query: 1621 SQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPE--DGIHELFP 1678
            SQPLVQTAVT I  P  L FT V   S+   W  P  Q++ YRV  +  E    + E+  
Sbjct: 1621 SQPLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINL 1680

Query: 1679 APDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTA--IPAPTDLKFTQVTPT 1736
            APD    +  + GL   ++Y VSV AL D + S+P  G  +T   +  P   + T  T T
Sbjct: 1681 APD--SSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATET 1738

Query: 1737 SLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALK 1796
            +++  W      +TG++V   P     P++   + PD  S  ++GL   T Y++ +Y L 
Sbjct: 1739 TITISWRTKTETITGFQVDAVPANGQTPIQR-TIKPDVRSYTITGLQPGTDYKIYLYTLN 1797

Query: 1797 DTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVD-AVPANGQT 1855
            D   S P   V+     +  P   R    T  ++ +SW+     ITG+ +    P +   
Sbjct: 1798 DNARSSPV--VIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPR 1855

Query: 1856 PIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATT 1915
             +    +P V   TITGL+PGT+Y IY+  L +N +S P++    T       L  L T 
Sbjct: 1856 EVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKT-----DELPQLVTL 1910

Query: 1916 PNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIA 1975
            P+                      P     E++    P   + T     PG + T   I 
Sbjct: 1911 PH----------------------PNLHGPEIL--DVPSTVQKTPFVTHPGYD-TGNGIQ 1945

Query: 1976 LKNNQKSEPLIGRKKTVQKTPFVTHPGYDTGNGIQ-----LPGTSGQQPSVGQQMIFEEH 2030
            L      +P +G++   ++  F       T   I+      P   G++  +G   I  E 
Sbjct: 1946 LPGTSGQQPSVGQQMIFEEHGFRRTTPPTTATPIRHRPRPYPPNVGEEIQIGH--IPRED 2003

Query: 2031 GFRRTTPPTTATPIRHRPRPYP-PNVGQEALSQTTISWAPFQDTSEYIISCHPVGTDEEP 2089
                  P        H P   P  + GQEALSQTTISWAPFQDTSEYIISCHPVGTDEEP
Sbjct: 2004 VDYHLYP--------HGPGLNPNASTGQEALSQTTISWAPFQDTSEYIISCHPVGTDEEP 2055

Query: 2090 LQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHKVREEVVTVGNSVNEGLNQPTDDS 2149
            LQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHKVREEVVTVGNSVNEGLNQPTDDS
Sbjct: 2056 LQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHKVREEVVTVGNSVNEGLNQPTDDS 2115

Query: 2150 CFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHDNGVNYKIGEKWD 2209
            CFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHDNGVNYKIGEKWD
Sbjct: 2116 CFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHDNGVNYKIGEKWD 2175

Query: 2210 RQGENGQMMSCTCLGNGKGEFKCDPHEATCYDDGKTYHVGEQWQKEYLGAICSCTCFGGQ 2269
            RQGENGQMMSCTCLGNGKGEFKCDPHEATCYDDGKTYHVGEQWQKEYLGAICSCTCFGGQ
Sbjct: 2176 RQGENGQMMSCTCLGNGKGEFKCDPHEATCYDDGKTYHVGEQWQKEYLGAICSCTCFGGQ 2235

Query: 2270 RGWRCDNCRRPGGEPSPEGTTGQSYNQYSQRYHQRTNTNVNCPIECFMPLDVQADREDSR 2329
            RGWRCDNCRRPGGEPSPEGTTGQSYNQYSQRYHQRTNTNVNCPIECFMPLDVQADREDSR
Sbjct: 2236 RGWRCDNCRRPGGEPSPEGTTGQSYNQYSQRYHQRTNTNVNCPIECFMPLDVQADREDSR 2295

Query: 2330 E 2330
            E
Sbjct: 2296 E 2296


>gi|47132549 fibronectin 1 isoform 6 preproprotein [Homo sapiens]
          Length = 2176

 Score = 3543 bits (9186), Expect = 0.0
 Identities = 1737/1986 (87%), Positives = 1793/1986 (90%), Gaps = 21/1986 (1%)

Query: 1    MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ 60
            MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ
Sbjct: 1    MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ 60

Query: 61   INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI 120
            INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI
Sbjct: 61   INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI 120

Query: 121  WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK 180
            WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK
Sbjct: 121  WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK 180

Query: 181  PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY 240
            PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY
Sbjct: 181  PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY 240

Query: 241  RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP 300
            RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP
Sbjct: 241  RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP 300

Query: 301  QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC 360
            QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC
Sbjct: 301  QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC 360

Query: 361  VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC 420
            VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC
Sbjct: 361  VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC 420

Query: 421  HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI 480
            HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI
Sbjct: 421  HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI 480

Query: 481  GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM 540
            GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM
Sbjct: 481  GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM 540

Query: 541  LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ 600
            LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ
Sbjct: 541  LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ 600

Query: 601  PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP 660
            PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP
Sbjct: 601  PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP 660

Query: 661  GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP 720
            GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP
Sbjct: 661  GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP 720

Query: 721  LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL 780
            LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL
Sbjct: 721  LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL 780

Query: 781  LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITG 840
            LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITG
Sbjct: 781  LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITG 840

Query: 841  YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG 900
            YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG
Sbjct: 841  YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG 900

Query: 901  TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT 960
            TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT
Sbjct: 901  TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT 960

Query: 961  FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP 1020
            FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP
Sbjct: 961  FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP 1020

Query: 1021 RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG 1080
            RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG
Sbjct: 1021 RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG 1080

Query: 1081 VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV 1140
            VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV
Sbjct: 1081 VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV 1140

Query: 1141 SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT 1200
            SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT
Sbjct: 1141 SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT 1200

Query: 1201 PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS 1260
            PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS
Sbjct: 1201 PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS 1260

Query: 1261 DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSD 1320
            DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSD
Sbjct: 1261 DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSD 1320

Query: 1321 NAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIA 1380
            NAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIA
Sbjct: 1321 NAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIA 1380

Query: 1381 PRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLL 1440
            PRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLL
Sbjct: 1381 PRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLL 1440

Query: 1441 IGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSK 1500
            IGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSK
Sbjct: 1441 IGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSK 1500

Query: 1501 STATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISV 1560
            STATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISV
Sbjct: 1501 STATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISV 1560

Query: 1561 KWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE 1620
            KWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE
Sbjct: 1561 KWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE 1620

Query: 1621 SQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPE--DGIHELFP 1678
            SQPLVQTAVT I  P  L FT V   S+   W  P  Q++ YRV  +  E    + E+  
Sbjct: 1621 SQPLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINL 1680

Query: 1679 APDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTA--IPAPTDLKFTQVTPT 1736
            APD    +  + GL   ++Y VSV AL D + S+P  G  +T   +  P   + T  T T
Sbjct: 1681 APD--SSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATET 1738

Query: 1737 SLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALK 1796
            +++  W      +TG++V   P     P++   + PD  S  ++GL   T Y++ +Y L 
Sbjct: 1739 TITISWRTKTETITGFQVDAVPANGQTPIQR-TIKPDVRSYTITGLQPGTDYKIYLYTLN 1797

Query: 1797 DTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVD-AVPANGQT 1855
            D   S P   V+     +  P   R    T  ++ +SW+     ITG+ +    P +   
Sbjct: 1798 DNARSSPV--VIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPR 1855

Query: 1856 PIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATT 1915
             +    +P V   TITGL+PGT+Y IY+  L +N +S P++    T  +A S      TT
Sbjct: 1856 EVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTGQEALSQ-----TT 1910

Query: 1916 PNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIA 1975
                 +SW P +   + YII     G+    +  R     T AT+TGL  G  Y I V A
Sbjct: 1911 -----ISWAPFQ-DTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEA 1964

Query: 1976 LKNNQK 1981
            LK+ Q+
Sbjct: 1965 LKDQQR 1970



 Score = 1061 bits (2743), Expect = 0.0
 Identities = 674/1635 (41%), Positives = 885/1635 (54%), Gaps = 189/1635 (11%)

Query: 768  LPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAP------------- 814
            +P    S  I  L PG  Y   +  I + G Q +      TT+   P             
Sbjct: 659  IPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPF 718

Query: 815  -----PDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTE-LNLPETANSVTLS 868
                    +V ++  +S VV W      ++G+R+ Y  S EG   + L+LP TA SV + 
Sbjct: 719  SPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIP 778

Query: 869  DLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWT 928
            DL PG +Y + +Y + E+ E + ++   +TT         +P D    +V D  + + W+
Sbjct: 779  DLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPD------APPDPTVDQVDDTSIVVRWS 832

Query: 929  PPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKP 988
             P++ +TGYR+   P          LP + N+   ++ L PGV Y   ++AV   +ES P
Sbjct: 833  RPQAPITGYRIVYSPSVEGSSTELNLPETANSVT-LSDLQPGVQYNITIYAVEENQESTP 891

Query: 989  LTAQQTTK-------LDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQ 1041
            +  QQ T        + +P +LQFV  TD  V + WTPP + +TGYR+ V       P +
Sbjct: 892  VVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDV--IPVNLPGE 949

Query: 1042 YNVGPSVSKYP---LRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEV 1098
            +     +S+     +  L P   Y   + A+   +ES   T   TT     +   +  E 
Sbjct: 950  HGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNE- 1008

Query: 1099 TETTIVITWTP--APRIGFKLGVRPSQGGEAPRE--VTSDSGSIVVSGLTPGVEYVYTIQ 1154
            T++T+++ WTP  A   G++L V  ++ G+ PR+  V        +  L P  EY  ++ 
Sbjct: 1009 TDSTVLVRWTPPRAQITGYRLTVGLTRRGQ-PRQYNVGPSVSKYPLRNLQPASEYTVSLV 1067

Query: 1155 VLRDGQERDAPIVNKVVTPLSPPTNL---HLEANPDTGVLTVSWERSTTPDITGYRITTT 1211
             ++  QE  +P    V T L P +++   + E    T V+T  W   T     G+++   
Sbjct: 1068 AIKGNQE--SPKATGVFTTLQPGSSIPPYNTEVTETTIVIT--W---TPAPRIGFKLGVR 1120

Query: 1212 PTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKE-SVPISDTIIPAVPPP 1270
            P+   QG      V +D  S     L+PG+EY  ++  ++D +E   PI + ++  + PP
Sbjct: 1121 PS---QGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPP 1177

Query: 1271 TDLRFTNIGPDT--MRVTWAPPPSIDLTNFLVRYSPVKNEE-DVAELSISPSDNAVVLTN 1327
            T+L      PDT  + V+W    + D+T + +  +P   ++ +  E  +    ++    N
Sbjct: 1178 TNLHL-EANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDN 1236

Query: 1328 LLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRAT-IT 1386
            L PG EY VSV +V +  ES P+       +  PT + F++I  ++  V W  P +  +T
Sbjct: 1237 LSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLT 1296

Query: 1387 GYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQST 1446
             + +R+ P        E  +  S N++ LTNL PGTEYVVS+ ++  + ES  L G+Q T
Sbjct: 1297 NFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKT 1356

Query: 1447 VSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATIS 1506
              D P  ++    T  S  + W AP  T+  YRI +     +   +E  VP S+++ T++
Sbjct: 1357 GLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLT 1416

Query: 1507 GLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSS 1566
             L PG +Y +++ A+ GR +SP      S    T  D P  ++V      S+ + W   +
Sbjct: 1417 NLTPGTEYVVSIVALNGREESPLLIGQQS----TVSDVPRDLEVVAATPTSLLISWDAPA 1472

Query: 1567 SPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGES----Q 1622
              V  YR+T     G  P +  T    ++  TI GL+P V+Y ++VYA    G+S    +
Sbjct: 1473 VTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSK 1532

Query: 1623 PLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDG 1682
            P+     T ID+P  +  TDV  +SI + W      V+ YRVT ++P++G         G
Sbjct: 1533 PISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVT-TTPKNGPGPTKTKTAG 1591

Query: 1683 EEDTA-ELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQ 1741
             + T   ++GL+P  EY VSV A +   ESQPL+ T  T IPAPTDLKFTQVTPTSLSAQ
Sbjct: 1592 PDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIPAPTDLKFTQVTPTSLSAQ 1651

Query: 1742 WTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTS 1801
            WTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTS
Sbjct: 1652 WTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTS 1711

Query: 1802 RPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTI 1861
            RPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTI
Sbjct: 1712 RPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTI 1771

Query: 1862 KPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLV 1921
            KPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLV
Sbjct: 1772 KPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLV 1831

Query: 1922 SWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQK 1981
            SWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQK
Sbjct: 1832 SWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQK 1891

Query: 1982 SEPLIGRKKTVQ----KTPFVTHPGYDTGNGI---------------QLPGTSGQQPSVG 2022
            SEPLIGRKKT Q    +T     P  DT   I               ++PGTS      G
Sbjct: 1892 SEPLIGRKKTGQEALSQTTISWAPFQDTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTG 1951

Query: 2023 QQMIFEEHGFRRTTPPTTATPIRHRPRPYPPNVG---QEALSQTTISWAPFQDT--SEYI 2077
                                  RH+ R     VG    E L+Q      P  D+    Y 
Sbjct: 1952 ----LTRGATYNIIVEALKDQQRHKVREEVVTVGNSVNEGLNQ------PTDDSCFDPYT 2001

Query: 2078 ISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRH-KVREEVVTVGN 2136
            +S + VG + E +                   + + ++ + L     H +         N
Sbjct: 2002 VSHYAVGDEWERMS-----------------ESGFKLLCQCLGFGSGHFRCDSSRWCHDN 2044

Query: 2137 SVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCD-SSRWC 2195
             VN  + +  D              G+  + MS       C CLG G G F+CD     C
Sbjct: 2045 GVNYKIGEKWDRQ------------GENGQMMS-------CTCLGNGKGEFKCDPHEATC 2085

Query: 2196 HDNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEATCYDDGKTYHVGEQWQKE 2255
            +D+G  Y +GE+W ++   G + SCTC G  +G                           
Sbjct: 2086 YDDGKTYHVGEQWQKE-YLGAICSCTCFGGQRG--------------------------- 2117

Query: 2256 YLGAICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYSQRYHQRTNTNVNCPIEC 2315
                            WRCDNCRRPGGEPSPEGTTGQSYNQYSQRYHQRTNTNVNCPIEC
Sbjct: 2118 ----------------WRCDNCRRPGGEPSPEGTTGQSYNQYSQRYHQRTNTNVNCPIEC 2161

Query: 2316 FMPLDVQADREDSRE 2330
            FMPLDVQADREDSRE
Sbjct: 2162 FMPLDVQADREDSRE 2176



 Score =  462 bits (1189), Expect = e-129
 Identities = 346/1230 (28%), Positives = 564/1230 (45%), Gaps = 79/1230 (6%)

Query: 628  IQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQY 687
            ++W+ PQ + I+ Y + + P    G   E  +P   NS T+  L+PGV Y   + ++++ 
Sbjct: 829  VRWSRPQ-APITGYRIVYSPSVE-GSSTELNLPETANSVTLSDLQPGVQYNITIYAVEE- 885

Query: 688  GHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTV 747
             +QE T       +T TP +    +     F           E+T     + W      V
Sbjct: 886  -NQESTPVVIQQETTGTPRSDTVPSPRDLQF----------VEVTDVKVTIMWTPPESAV 934

Query: 748  SGFRVEY-ELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTS 806
            +G+RV+   ++  G+  Q L + S  T   +  L PG  Y   V+ +S  G +S  L+  
Sbjct: 935  TGYRVDVIPVNLPGEHGQRLPI-SRNTFAEVTGLSPGVTYYFKVFAVSH-GRESKPLTAQ 992

Query: 807  QTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVT 866
            QTT  DAP +       D++++VRW+ P+A ITGYR+    +  G   + N+  + +   
Sbjct: 993  QTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYP 1052

Query: 867  LSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIM 926
            L +LQP  +Y +++ A++ NQES P      TT  P S   P        EVT+  + I 
Sbjct: 1053 LRNLQPASEYTVSLVAIKGNQES-PKATGVFTTLQPGSSIPPYN-----TEVTETTIVIT 1106

Query: 927  WTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRE- 985
            WTP      G+++ V P    G    R   S +    V+GL+PGV Y + +  +  G+E 
Sbjct: 1107 WTPAPRI--GFKLGVRPSQ--GGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQER 1162

Query: 986  SKPLTAQQTTKLDAPTNLQFVNETDSTVL-VRW---TPPRAQITGYRLTVGLT--RRGQP 1039
              P+  +  T L  PTNL      D+ VL V W   T P   ITGYR+T   T  ++G  
Sbjct: 1163 DAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTP--DITGYRITTTPTNGQQGNS 1220

Query: 1040 RQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYN---T 1096
             +  V    S     NL P  EY VS+  +K ++ES   +       P    PP +   T
Sbjct: 1221 LEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVP----PPTDLRFT 1276

Query: 1097 EVTETTIVITWTPAPRI---GFKLGVRPSQGGE--APREVTSDSGSIVVSGLTPGVEYVY 1151
             +   T+ +TW P P I    F +   P +  E  A   ++    ++V++ L PG EYV 
Sbjct: 1277 NIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVV 1336

Query: 1152 TIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSW--ERSTTPDITGYRIT 1209
            ++  + + Q    P+  +  T L  PT +   ++      TV W   R+T   ITGYRI 
Sbjct: 1337 SVSSVYE-QHESTPLRGRQKTGLDSPTGIDF-SDITANSFTVHWIAPRAT---ITGYRIR 1391

Query: 1210 TTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPP 1269
              P +   G   E+ V   ++S T  NL+PG EY VS+  +   +ES  +          
Sbjct: 1392 HHPEHFS-GRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDV 1450

Query: 1270 PTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLL 1329
            P DL      P ++ ++W   P++ +  + + Y        V E ++  S +   ++ L 
Sbjct: 1451 PRDLEVVAATPTSLLISW-DAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLK 1509

Query: 1330 PGTEYVVSVSSVYEQHEST----PLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATI 1385
            PG +Y ++V +V  + +S     P+    +T +D P+ +  +D+  NS +V W+   + +
Sbjct: 1510 PGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPV 1569

Query: 1386 TGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQS 1445
            TGYR+   P++  G  +       +  +T+  L P  EYVVS+ A N   ES  L+    
Sbjct: 1570 TGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAV 1629

Query: 1446 TVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATI 1505
            T    P DL+    TPTSL   W  P V +  YR+         P++E  +    S+  +
Sbjct: 1630 TTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVV 1689

Query: 1506 SGLKPGVDYTITVYAVTGRGDSPASSKPIS--INYRTEIDKPSQMQVTDVQDNSISVKWL 1563
            SGL     Y ++VYA+        +S+P    +     +  P + +VTD  + +I++ W 
Sbjct: 1690 SGLMVATKYEVSVYALK----DTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWR 1745

Query: 1564 PSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQP 1623
              +  +TG++V   P NG  P + +T  PD    TI GLQP  +Y + +Y  N +  S P
Sbjct: 1746 TKTETITGFQVDAVPANGQTPIQ-RTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSP 1804

Query: 1624 LVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGE 1683
            +V  A T ID P  L F     +S+ ++W+ P+ +++ Y + Y  P     E+ P P   
Sbjct: 1805 VVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPG 1864

Query: 1684 EDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWT 1743
               A + GL PG+EYT+ V+AL ++ +S+PLIG + T   A        ++ T++S  W 
Sbjct: 1865 VTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTGQEA--------LSQTTIS--WA 1914

Query: 1744 PPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRP 1803
            P     + Y +   P        +  +   S+S  ++GL     Y + V ALKD    + 
Sbjct: 1915 PFQ-DTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHKV 1973

Query: 1804 AQGVVTTLENVSPPRRARVTDATETTITIS 1833
             + VVT   +V+        D+     T+S
Sbjct: 1974 REEVVTVGNSVNEGLNQPTDDSCFDPYTVS 2003



 Score =  443 bits (1139), Expect = e-123
 Identities = 355/1215 (29%), Positives = 562/1215 (46%), Gaps = 123/1215 (10%)

Query: 1005 FVNETDS---TVLVRWTPPR-AQITGYRLTVGLTRR-GQPRQYNVGPSVSKYPLRNLQPA 1059
            F+ ET S   +  ++W  P+ + I+ Y L        G+ ++  +   ++ Y ++ L+P 
Sbjct: 615  FITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPG 674

Query: 1060 SEYTVSLVAIK--GNQE----------------SPKATGVFTTLQPGSSIPPYNTEVTET 1101
              Y   L++I+  G+QE                S   TG  T   P  +     TE+T +
Sbjct: 675  VVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITAS 734

Query: 1102 TIVITWTPAPRI--GFKLGVRPSQGGEAPR--EVTSDSGSIVVSGLTPGVEYVYTI-QVL 1156
            + V++W  A     GF++    S+ G+ P+  ++ S + S+ +  L PG +Y+  + Q+ 
Sbjct: 735  SFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQIS 794

Query: 1157 RDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQ 1216
             DG++      ++   P +PP    ++   DT ++ V W R   P ITGYRI  +P+   
Sbjct: 795  EDGEQSLILSTSQTTAPDAPPDPT-VDQVDDTSIV-VRWSRPQAP-ITGYRIVYSPS--V 849

Query: 1217 QGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPI-----------SDTIIP 1265
            +G+S E  +    +S T  +L PG++YN+++Y V++++ES P+           SDT   
Sbjct: 850  EGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDT--- 906

Query: 1266 AVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNE-EDVAELSISPSDNAVV 1324
             VP P DL+F  +    + + W PP S  +T + V   PV    E    L IS +  A V
Sbjct: 907  -VPSPRDLQFVEVTDVKVTIMWTPPESA-VTGYRVDVIPVNLPGEHGQRLPISRNTFAEV 964

Query: 1325 LTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRAT 1384
             T L PG  Y   V +V    ES PL  +Q T LD+PT + F + T ++  V W  PRA 
Sbjct: 965  -TGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQ 1023

Query: 1385 ITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQ 1444
            ITGYR+        G+PR+  V  S +   L NL P +EY VS+VA+ G +ESP   G  
Sbjct: 1024 ITGYRLTVGLTR-RGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVF 1082

Query: 1445 STV----SDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSK 1500
            +T+    S  P + EV   T T+++I+W  PA  + +        GG +P +   V    
Sbjct: 1083 TTLQPGSSIPPYNTEV---TETTIVITW-TPAPRIGFKLGVRPSQGGEAPRE---VTSDS 1135

Query: 1501 STATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSI-S 1559
             +  +SGL PGV+Y  T+  +    D      PI     T +  P+ + +    D  + +
Sbjct: 1136 GSIVVSGLTPGVEYVYTIQVLR---DGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLT 1192

Query: 1560 VKWLPSSSP-VTGYRVTTTPKNGP-GPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNP 1617
            V W  S++P +TGYR+TTTP NG  G +  +    DQ+  T + L P +EY VSVY    
Sbjct: 1193 VSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKD 1252

Query: 1618 SGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQG-QVSRYRVTYS--SPEDGIH 1674
              ES P+  T +  +  P  L FT++  D++++ W  P    ++ + V YS    E+ + 
Sbjct: 1253 DKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVA 1312

Query: 1675 ELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVT 1734
            EL  +P   ++   L  L PG+EY VSV ++++  ES PL G Q T + +PT + F+ +T
Sbjct: 1313 ELSISPS--DNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDIT 1370

Query: 1735 PTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYA 1794
              S +  W  P   +TGYR+R  P+  +G  +E  +    +S+ ++ L   T+Y VS+ A
Sbjct: 1371 ANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVA 1430

Query: 1795 LKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQ 1854
            L     S    G  +T+ +V  PR   V  AT T++ ISW     T+  +++      G 
Sbjct: 1431 LNGREESPLLIGQQSTVSDV--PRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGN 1488

Query: 1855 TPIQRTIKPDVRSY-TITGLQPGTDYKIYLYTLNDN----ARSSPVVIDASTAIDAPSNL 1909
            +P+Q    P  +S  TI+GL+PG DY I +Y +       A S P+ I+  T ID PS +
Sbjct: 1489 SPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQM 1548

Query: 1910 RFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEY 1969
            +      NS+ V W P  + +TGY +       P         P  TE TI GL+P  EY
Sbjct: 1549 QVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEY 1608

Query: 1970 TIYVIALKNNQKSEPLIGRK----------KTVQKTPFVTHPGYDTGNGIQLPG------ 2013
             + V A   + +S+PL+             K  Q TP      +   N +QL G      
Sbjct: 1609 VVSVYAQNPSGESQPLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPN-VQLTGYRVRVT 1667

Query: 2014 ---------------------TSGQQPSVGQQMIFEEHGFRRTTPPT--TATPIRHRPRP 2050
                                  SG   +   ++         T+ P     T + +   P
Sbjct: 1668 PKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPP 1727

Query: 2051 YPPNVGQEALSQTTISWAPFQDT-SEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRG 2109
                V     +  TISW    +T + + +   P    + P+Q  +     S T+TGL  G
Sbjct: 1728 RRARVTDATETTITISWRTKTETITGFQVDAVP-ANGQTPIQRTIKPDVRSYTITGLQPG 1786

Query: 2110 ATYNIIVEALKDQQR 2124
              Y I +  L D  R
Sbjct: 1787 TDYKIYLYTLNDNAR 1801



 Score =  115 bits (287), Expect = 7e-25
 Identities = 57/129 (44%), Positives = 74/129 (57%), Gaps = 5/129 (3%)

Query: 2147 DDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHDNGVNYKIGE 2206
            +++CFD YT + Y VGD +ER  +S     C C+G G G   C  +  CH+ G +YKIG+
Sbjct: 94   EETCFDKYTGNTYRVGDTYERPKDSMI-WDCTCIGAGRGRISCTIANRCHEGGQSYKIGD 152

Query: 2207 KWDRQGE-NGQMMSCTCLGNGKGEFKCDPHEATCYDD--GKTYHVGEQWQKEYLG-AICS 2262
             W R  E  G M+ C CLGNGKGE+ C P    C+D   G +Y VGE W+K Y G  +  
Sbjct: 153  TWRRPHETGGYMLECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQGWMMVD 212

Query: 2263 CTCFGGQRG 2271
            CTC G   G
Sbjct: 213  CTCLGEGSG 221



 Score =  115 bits (287), Expect = 7e-25
 Identities = 57/129 (44%), Positives = 74/129 (57%), Gaps = 5/129 (3%)

Query: 94   EETCFDKYTGNTYRVGDTYERPKDSMI-WDCTCIGAGRGRISCTIANRCHEGGQSYKIGD 152
            +++CFD YT + Y VGD +ER  +S     C C+G G G   C  +  CH+ G +YKIG+
Sbjct: 1993 DDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHDNGVNYKIGE 2052

Query: 153  TWRRPHETGGYMLECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQGWMMVD 212
             W R  E  G M+ C CLGNGKGE+ C P    C+D   G +Y VGE W+K Y G  +  
Sbjct: 2053 KWDRQGE-NGQMMSCTCLGNGKGEFKCDPHEATCYDD--GKTYHVGEQWQKEYLG-AICS 2108

Query: 213  CTCLGEGSG 221
            CTC G   G
Sbjct: 2109 CTCFGGQRG 2117



 Score = 98.6 bits (244), Expect = 6e-20
 Identities = 54/172 (31%), Positives = 73/172 (42%), Gaps = 34/172 (19%)

Query: 2130 EVVTVGNSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRC 2189
            E V +GN   E   +P  + CFD    + Y VG+ WE+  +    + C CLG GSG   C
Sbjct: 166  ECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITC 225

Query: 2190 DSSRWCHDNG--VNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPH------------ 2235
             S   C+D     +Y+IG+ W ++   G ++ C C GNG+GE+KC+ H            
Sbjct: 226  TSRNRCNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGP 285

Query: 2236 ----EATCY----------------DDGKTYHVGEQWQKEYLGAICSCTCFG 2267
                 A  Y                D G  Y VG QW K        CTC G
Sbjct: 286  FTDVRAAVYQPQPHPQPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLG 337



 Score = 98.6 bits (244), Expect = 6e-20
 Identities = 54/172 (31%), Positives = 73/172 (42%), Gaps = 34/172 (19%)

Query: 166  ECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITC 225
            E V +GN   E   +P  + CFD    + Y VG+ WE+  +    + C CLG GSG   C
Sbjct: 1976 EVVTVGNSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRC 2035

Query: 226  TSRNRCNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGP 285
             S   C+D     +Y+IG+ W ++   G ++ C C GNG+GE+KC+ H            
Sbjct: 2036 DSSRWCHDNG--VNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPH------------ 2081

Query: 286  FTDVRAAVYQPQPHPQPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLG 337
                 A  Y                D G  Y VG QW K        CTC G
Sbjct: 2082 ----EATCY----------------DDGKTYHVGEQWQKEYLGAICSCTCFG 2113



 Score = 90.9 bits (224), Expect = 1e-17
 Identities = 40/123 (32%), Positives = 65/123 (52%), Gaps = 8/123 (6%)

Query: 2159 YAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHD----NGVNYKIGEKWDRQGEN 2214
            Y +GD+W++  + G  + C C+G G G + C +     D    + + Y + + + ++ E 
Sbjct: 478  YRIGDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEE 537

Query: 2215 GQMMSCTCLGNGKGEFKCDPHEATCYDD--GKTYHVGEQWQKEYLGAICSCTCFG-GQRG 2271
            G M++CTC G G+G +KCDP +  C D   G  Y +G+ W+K   G    C C+G G   
Sbjct: 538  GHMLNCTCFGQGRGRWKCDPVD-QCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGE 596

Query: 2272 WRC 2274
            W C
Sbjct: 597  WHC 599



 Score = 90.9 bits (224), Expect = 1e-17
 Identities = 40/123 (32%), Positives = 65/123 (52%), Gaps = 8/123 (6%)

Query: 478  YRIGDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEE 537
            Y +GD+W++  + G  + C C+G G G + C +     D    + + Y + + + ++ E 
Sbjct: 2005 YAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHD----NGVNYKIGEKWDRQGEN 2060

Query: 538  GHMLNCTCFGQGRGRWKCDPVD-QCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGE 596
            G M++CTC G G+G +KCDP +  C D   G  Y +G+ W+K   G    C C+G G   
Sbjct: 2061 GQMMSCTCLGNGKGEFKCDPHEATCYDD--GKTYHVGEQWQKEYLGAICSCTCFG-GQRG 2117

Query: 597  WHC 599
            W C
Sbjct: 2118 WRC 2120



 Score = 88.2 bits (217), Expect = 9e-17
 Identities = 45/124 (36%), Positives = 65/124 (52%), Gaps = 7/124 (5%)

Query: 2159 YAVGDEWERMSESG-FKLLCQCLGFGSGHFRCDS-SRWCHDN--GVNYKIGEKWDRQGEN 2214
            Y +GD W R  E+G + L C CLG G G + C   +  C D+  G +Y +GE W++  + 
Sbjct: 148  YKIGDTWRRPHETGGYMLECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQG 207

Query: 2215 GQMMSCTCLGNGKGEFKCDPHEATCYDDGKT-YHVGEQW-QKEYLGAICSCTCFGGQRG- 2271
              M+ CTCLG G G   C         D +T Y +G+ W +K+  G +  C C G  RG 
Sbjct: 208  WMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGE 267

Query: 2272 WRCD 2275
            W+C+
Sbjct: 268  WKCE 271



 Score = 88.2 bits (217), Expect = 9e-17
 Identities = 45/124 (36%), Positives = 65/124 (52%), Gaps = 7/124 (5%)

Query: 148  YKIGDTWRRPHETGGYMLECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQG 207
            Y +GD W R  E+G + L C CLG G G + C   +  C D+  G +Y +GE W++  + 
Sbjct: 2005 YAVGDEWERMSESG-FKLLCQCLGFGSGHFRCDS-SRWCHDN--GVNYKIGEKWDRQGEN 2060

Query: 208  WMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGE 267
              M+ CTCLG G G   C         D +T Y +G+ W +K+  G +  C C G  RG 
Sbjct: 2061 GQMMSCTCLGNGKGEFKCDPHEATCYDDGKT-YHVGEQW-QKEYLGAICSCTCFGGQRG- 2117

Query: 268  WKCE 271
            W+C+
Sbjct: 2118 WRCD 2121



 Score = 79.7 bits (195), Expect = 3e-14
 Identities = 37/84 (44%), Positives = 54/84 (64%), Gaps = 5/84 (5%)

Query: 2197 DNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEA---TCYDDGKTYHVGEQWQ 2253
            + GV Y+IG++WD+Q + G MM CTC+GNG+GE+ C  +      C  D  TY+V + + 
Sbjct: 473  NEGVMYRIGDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFH 532

Query: 2254 KEY-LGAICSCTCFGGQRG-WRCD 2275
            K +  G + +CTCFG  RG W+CD
Sbjct: 533  KRHEEGHMLNCTCFGQGRGRWKCD 556



 Score = 79.7 bits (195), Expect = 3e-14
 Identities = 37/84 (44%), Positives = 54/84 (64%), Gaps = 5/84 (5%)

Query: 473  NEGVMYRIGDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFH 532
            + GV Y+IG++WD+Q + G MM CTC+GNG+GE+ C  +      C  D  TY+V + + 
Sbjct: 2043 DNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEA---TCYDDGKTYHVGEQWQ 2099

Query: 533  KRHEEGHMLNCTCFGQGRGRWKCD 556
            K +  G + +CTCFG  RG W+CD
Sbjct: 2100 KEY-LGAICSCTCFGGQRG-WRCD 2121



 Score = 63.5 bits (153), Expect = 2e-09
 Identities = 32/82 (39%), Positives = 46/82 (56%), Gaps = 7/82 (8%)

Query: 2195 CHDNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPH---EATCYD--DGKTYHVG 2249
            C+DNG +Y+I ++W+R    G  + CTC G  +G F C+     E TC+D   G TY VG
Sbjct: 52   CYDNGKHYQINQQWERT-YLGNALVCTCYGGSRG-FNCESKPEAEETCFDKYTGNTYRVG 109

Query: 2250 EQWQKEYLGAICSCTCFGGQRG 2271
            + +++     I  CTC G  RG
Sbjct: 110  DTYERPKDSMIWDCTCIGAGRG 131



 Score = 63.5 bits (153), Expect = 2e-09
 Identities = 32/82 (39%), Positives = 46/82 (56%), Gaps = 7/82 (8%)

Query: 52   CYDNGKHYQINQQWERT-YLGNALVCTCYGGSRG-FNCESKPEAEETCFDKYTGNTYRVG 109
            C+DNG +Y+I ++W+R    G  + CTC G  +G F C+     E TC+D   G TY VG
Sbjct: 2041 CHDNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPH---EATCYD--DGKTYHVG 2095

Query: 110  DTYERPKDSMIWDCTCIGAGRG 131
            + +++     I  CTC G  RG
Sbjct: 2096 EQWQKEYLGAICSCTCFGGQRG 2117



 Score = 62.0 bits (149), Expect = 7e-09
 Identities = 37/107 (34%), Positives = 49/107 (45%), Gaps = 10/107 (9%)

Query: 2134 VGNSVNE----GLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRC 2189
            VGN   E      +Q  D    D  T   Y V D + +  E G  L C C G G G ++C
Sbjct: 499  VGNGRGEWTCIAYSQLRDQCIVDDIT---YNVNDTFHKRHEEGHMLNCTCFGQGRGRWKC 555

Query: 2190 DSSRWCHDN--GVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDP 2234
            D    C D+  G  Y+IG+ W++   +G    C C G G GE+ C P
Sbjct: 556  DPVDQCQDSETGTFYQIGDSWEKY-VHGVRYQCYCYGRGIGEWHCQP 601



 Score = 62.0 bits (149), Expect = 7e-09
 Identities = 37/107 (34%), Positives = 49/107 (45%), Gaps = 10/107 (9%)

Query: 499  VGNGRGEWTCIAYSQLRDQCIVDDIT---YNVNDTFHKRHEEGHMLNCTCFGQGRGRWKC 555
            VGN   E      +Q  D    D  T   Y V D + +  E G  L C C G G G ++C
Sbjct: 1980 VGNSVNE----GLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRC 2035

Query: 556  DPVDQCQDSETGTFYQIGDSWEKY-VHGVRYQCYCYGRGIGEWHCQP 601
            D    C D+  G  Y+IG+ W++   +G    C C G G GE+ C P
Sbjct: 2036 DSSRWCHDN--GVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDP 2080



 Score = 57.8 bits (138), Expect = 1e-07
 Identities = 24/62 (38%), Positives = 35/62 (56%), Gaps = 6/62 (9%)

Query: 2239 CYDDGKTYHVGEQWQKEYLGAICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYS 2298
            CYD+GK Y + +QW++ YLG    CTC+GG RG+ C++      +P  E T    Y   +
Sbjct: 52   CYDNGKHYQINQQWERTYLGNALVCTCYGGSRGFNCES------KPEAEETCFDKYTGNT 105

Query: 2299 QR 2300
             R
Sbjct: 106  YR 107



 Score = 57.8 bits (138), Expect = 1e-07
 Identities = 24/62 (38%), Positives = 35/62 (56%), Gaps = 6/62 (9%)

Query: 52   CYDNGKHYQINQQWERTYLGNALVCTCYGGSRGFNCES------KPEAEETCFDKYTGNT 105
            CYD+GK Y + +QW++ YLG    CTC+GG RG+ C++      +P  E T    Y   +
Sbjct: 2085 CYDDGKTYHVGEQWQKEYLGAICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYS 2144

Query: 106  YR 107
             R
Sbjct: 2145 QR 2146



 Score = 50.1 bits (118), Expect = 3e-05
 Identities = 31/110 (28%), Positives = 42/110 (38%), Gaps = 34/110 (30%)

Query: 2150 CFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDS------------------ 2191
            C D  T + Y +GD W +    G  L C C G G G ++C+                   
Sbjct: 231  CNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVR 290

Query: 2192 ---------------SRWCHDNGVNYKIGEKWDRQGENGQMMSCTCLGNG 2226
                                D+GV Y +G +W +   N QM+ CTCLGNG
Sbjct: 291  AAVYQPQPHPQPPPYGHCVTDSGVVYSVGMQWLKTQGNKQML-CTCLGNG 339



 Score = 50.1 bits (118), Expect = 3e-05
 Identities = 31/110 (28%), Positives = 42/110 (38%), Gaps = 34/110 (30%)

Query: 231  CNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVR 290
            C D  T + Y +GD W +    G  L C C G G G ++C+                   
Sbjct: 1996 CFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDS------------------ 2037

Query: 291  AAVYQPQPHPQPPPYGHCVTDSGVVYSVGMQWLKTQGNKQML-CTCLGNG 339
                                D+GV Y +G +W +   N QM+ CTCLGNG
Sbjct: 2038 ---------------SRWCHDNGVNYKIGEKWDRQGENGQMMSCTCLGNG 2072


>gi|47132557 fibronectin 1 isoform 1 preproprotein [Homo sapiens]
          Length = 2477

 Score = 3008 bits (7798), Expect = 0.0
 Identities = 1514/2135 (70%), Positives = 1655/2135 (77%), Gaps = 74/2135 (3%)

Query: 1    MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ 60
            MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ
Sbjct: 1    MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ 60

Query: 61   INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI 120
            INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI
Sbjct: 61   INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI 120

Query: 121  WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK 180
            WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK
Sbjct: 121  WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK 180

Query: 181  PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY 240
            PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY
Sbjct: 181  PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY 240

Query: 241  RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP 300
            RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP
Sbjct: 241  RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP 300

Query: 301  QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC 360
            QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC
Sbjct: 301  QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC 360

Query: 361  VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC 420
            VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC
Sbjct: 361  VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC 420

Query: 421  HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI 480
            HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI
Sbjct: 421  HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI 480

Query: 481  GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM 540
            GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM
Sbjct: 481  GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM 540

Query: 541  LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ 600
            LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ
Sbjct: 541  LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ 600

Query: 601  PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP 660
            PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP
Sbjct: 601  PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP 660

Query: 661  GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP 720
            GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP
Sbjct: 661  GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP 720

Query: 721  LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL 780
            LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL
Sbjct: 721  LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL 780

Query: 781  LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITG 840
            LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITG
Sbjct: 781  LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITG 840

Query: 841  YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG 900
            YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG
Sbjct: 841  YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG 900

Query: 901  TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT 960
            TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT
Sbjct: 901  TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT 960

Query: 961  FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP 1020
            FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP
Sbjct: 961  FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP 1020

Query: 1021 RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG 1080
            RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG
Sbjct: 1021 RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG 1080

Query: 1081 VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV 1140
            VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV
Sbjct: 1081 VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV 1140

Query: 1141 SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT 1200
            SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT
Sbjct: 1141 SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT 1200

Query: 1201 PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS 1260
            PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS
Sbjct: 1201 PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS 1260

Query: 1261 DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSD 1320
            DTIIP VP  TDL F +I   ++ + W P  S  +  + +          + E  +  S 
Sbjct: 1261 DTIIPEVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIFEDFVDSSV 1320

Query: 1321 NAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIA 1380
                +T L PG +Y +SV ++    ES P    Q+T +  PT + F++I  ++  V W  
Sbjct: 1321 GYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAP 1380

Query: 1381 PRA-TITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPL 1439
            P +  +T + +R+ P        E  +  S N++ LTNL PGTEYVVS+ ++  + ES  
Sbjct: 1381 PPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTP 1440

Query: 1440 LIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGS 1499
            L G+Q T  D P  ++    T  S  + W AP  T+  YRI +     +   +E  VP S
Sbjct: 1441 LRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHS 1500

Query: 1500 KSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSIS 1559
            +++ T++ L PG +Y +++ A+ GR +SP     +     T  D P  ++V      S+ 
Sbjct: 1501 RNSITLTNLTPGTEYVVSIVALNGREESPL----LIGQQSTVSDVPRDLEVVAATPTSLL 1556

Query: 1560 VKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSG 1619
            + W   +  V  YR+T     G  P +  T    ++  TI GL+P V+Y ++VYA    G
Sbjct: 1557 ISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRG 1616

Query: 1620 E----SQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHE 1675
            +    S+P+     T ID+P  +  TDV  +SI + W      V+ YRVT ++P++G   
Sbjct: 1617 DSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVT-TTPKNGPGP 1675

Query: 1676 LFPAPDGEEDT-AELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVT 1734
                  G + T   ++GL+P  EY VSV A +   ESQPL+ T  T I  P  L FT V 
Sbjct: 1676 TKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVD 1735

Query: 1735 PTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPD--SSSVVVSGLMVATKYEVSV 1792
              S+   W  P  Q++ YRV  +  E    + E+  APD    +  + GL   ++Y VSV
Sbjct: 1736 VDSIKIAWESPQGQVSRYRVTYSSPE--DGIHELFPAPDGEEDTAELQGLRPGSEYTVSV 1793

Query: 1793 YALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPAN 1852
             AL D + S+P  G  +T   +  P   + T  T T+++  W      +TG++V   P  
Sbjct: 1794 VALHDDMESQPLIGTQSTA--IPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKE 1851

Query: 1853 GQTPIQR-TIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPV--VIDASTAIDAPSNL 1909
               P++   + PD  S  ++GL   T Y++ +Y L D   S P   V+     +  P   
Sbjct: 1852 KTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRA 1911

Query: 1910 RFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEY 1969
            R    T  ++ +SW+     ITG+ +    P +    +    +P V   TITGL+PGT+Y
Sbjct: 1912 RVTDATETTITISWRTKTETITGFQVD-AVPANGQTPIQRTIKPDVRSYTITGLQPGTDY 1970

Query: 1970 TIYVIALKNNQKSEPLIGRKKTVQKTPFVTHPGYDTGNGIQLPGTSGQQPSVGQQMIFEE 2029
             IY+  L +N +S P++    T    P        T N + +     +    G  + +E+
Sbjct: 1971 KIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEK 2030

Query: 2030 HGFRRTTPPTTATPIRHRPRPYPPNVGQEALSQTTISWAPFQDTSEYIISCHPVGTDEEP 2089
             G    +PP    P   RPRP                                       
Sbjct: 2031 PG----SPPREVVP---RPRP--------------------------------------- 2044

Query: 2090 LQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQR 2124
                     T AT+TGL  G  Y I V ALK+ Q+
Sbjct: 2045 -------GVTEATITGLEPGTEYTIYVIALKNNQK 2072



 Score = 2356 bits (6106), Expect = 0.0
 Identities = 1235/1752 (70%), Positives = 1344/1752 (76%), Gaps = 122/1752 (6%)

Query: 659  IPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPF 718
            +P    S  I  L PG  Y   +  I + G Q +      TT+   P             
Sbjct: 768  LPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAP------------- 814

Query: 719  SPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIP 778
                    +V ++  +S VV W      ++G+R+ Y  S EG   + L+LP TA SV + 
Sbjct: 815  -----PDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTE-LNLPETANSVTLS 868

Query: 779  DLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPD------APPDPTVDQVDDTSIVVRWS 832
            DL PG +Y + +Y + E+ E + ++   +TT         +P D    +V D  + + W+
Sbjct: 869  DLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWT 928

Query: 833  RPQAPITGYRIVYSPSVEGSSTELNLPETANSVT-LSDLQPGVQYNITIYAVEENQESTP 891
             P++ +TGYR+   P          LP + N+   ++ L PGV Y   ++AV   +ES P
Sbjct: 929  PPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKP 988

Query: 892  VVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHG 951
            +  QQ T        + +P +LQFV  TD  V + WTPP + +TGYR+ V      G   
Sbjct: 989  LTAQQTTK-------LDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTV------GLTR 1035

Query: 952  QRLPISRNTFAEVT-----GLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFV 1006
            +  P   N    V+      L P   Y   + A+   +ES   T   TT     +   + 
Sbjct: 1036 RGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYN 1095

Query: 1007 NE-TDSTVLVRWTPPRAQITGYRLTVGLTRRGQ-PRQYNVGPSVSKYPLRNLQPASEYTV 1064
             E T++T+++ WTP  A   G++L V  ++ G+ PR+  V        +  L P  EY  
Sbjct: 1096 TEVTETTIVITWTP--APRIGFKLGVRPSQGGEAPRE--VTSDSGSIVVSGLTPGVEYVY 1151

Query: 1065 SLVAIKGNQE--SPKATGVFTTLQPGSSIPPYNTEVTETTIVIT--W---TPAPRIGFKL 1117
            ++  ++  QE  +P    V T L P +++   + E    T V+T  W   T     G+++
Sbjct: 1152 TIQVLRDGQERDAPIVNKVVTPLSPPTNL---HLEANPDTGVLTVSWERSTTPDITGYRI 1208

Query: 1118 GVRPS---QGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPL 1174
               P+   QG      V +D  S     L+PG+EY  ++  ++D +E   PI + ++  +
Sbjct: 1209 TTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKE-SVPISDTIIPEV 1267

Query: 1175 SPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTF 1234
               T+L      D+ +  + W    +  I GYRIT     G+     E+ V +     T 
Sbjct: 1268 PQLTDLSFVDITDSSI-GLRWTPLNSSTIIGYRITVVAA-GEGIPIFEDFVDSSVGYYTV 1325

Query: 1235 DNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSID 1294
              L PG++Y++SV T+ +  ES P + T   AVPPPTDLRFTNIGPDTMRVTWAPPPSID
Sbjct: 1326 TGLEPGIDYDISVITLINGGESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAPPPSID 1385

Query: 1295 LTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQ 1354
            LTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQ
Sbjct: 1386 LTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQ 1445

Query: 1355 KTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSIT 1414
            KTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSIT
Sbjct: 1446 KTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSIT 1505

Query: 1415 LTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVT 1474
            LTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVT
Sbjct: 1506 LTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVT 1565

Query: 1475 VRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPI 1534
            VRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPI
Sbjct: 1566 VRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPI 1625

Query: 1535 SINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQ 1594
            SINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQ
Sbjct: 1626 SINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQ 1685

Query: 1595 TEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWES 1654
            TEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWES
Sbjct: 1686 TEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWES 1745

Query: 1655 PQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPL 1714
            PQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPL
Sbjct: 1746 PQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPL 1805

Query: 1715 IGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDS 1774
            IGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDS
Sbjct: 1806 IGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDS 1865

Query: 1775 SSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISW 1834
            SSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISW
Sbjct: 1866 SSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISW 1925

Query: 1835 RTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSP 1894
            RTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSP
Sbjct: 1926 RTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSP 1985

Query: 1895 VVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPG 1954
            VVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPG
Sbjct: 1986 VVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPG 2045

Query: 1955 VTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKT----------------------- 1991
            VTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKT                       
Sbjct: 2046 VTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELPQLVTLPHPNLHGPEILDVP 2105

Query: 1992 --VQKTPFVTHPGYDTGNGIQLPGTSGQQPSVGQQMIFEEHGFRRTTPPTTATPIRHRPR 2049
              VQKTPFVTHPGYDTGNGIQLPGTSGQQPSVGQQMIFEEHGFRRTTPPTTATPIRHRPR
Sbjct: 2106 STVQKTPFVTHPGYDTGNGIQLPGTSGQQPSVGQQMIFEEHGFRRTTPPTTATPIRHRPR 2165

Query: 2050 PYPPNVG-------------------------------QEALSQTTISWAPFQDTSEYII 2078
            PYPPNVG                               QEALSQTTISWAPFQDTSEYII
Sbjct: 2166 PYPPNVGEEIQIGHIPREDVDYHLYPHGPGLNPNASTGQEALSQTTISWAPFQDTSEYII 2225

Query: 2079 SCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHKVREEVVTVGNSV 2138
            SCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHKVREEVVTVGNSV
Sbjct: 2226 SCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHKVREEVVTVGNSV 2285

Query: 2139 NEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHDN 2198
            NEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHDN
Sbjct: 2286 NEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHDN 2345

Query: 2199 GVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEATCYDDGKTYHVGEQWQKEYLG 2258
            GVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEATCYDDGKTYHVGEQWQKEYLG
Sbjct: 2346 GVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEATCYDDGKTYHVGEQWQKEYLG 2405

Query: 2259 AICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYSQRYHQRTNTNVNCPIECFMP 2318
            AICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYSQRYHQRTNTNVNCPIECFMP
Sbjct: 2406 AICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYSQRYHQRTNTNVNCPIECFMP 2465

Query: 2319 LDVQADREDSRE 2330
            LDVQADREDSRE
Sbjct: 2466 LDVQADREDSRE 2477



 Score =  115 bits (287), Expect = 7e-25
 Identities = 57/129 (44%), Positives = 74/129 (57%), Gaps = 5/129 (3%)

Query: 2147 DDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHDNGVNYKIGE 2206
            +++CFD YT + Y VGD +ER  +S     C C+G G G   C  +  CH+ G +YKIG+
Sbjct: 94   EETCFDKYTGNTYRVGDTYERPKDSMI-WDCTCIGAGRGRISCTIANRCHEGGQSYKIGD 152

Query: 2207 KWDRQGE-NGQMMSCTCLGNGKGEFKCDPHEATCYDD--GKTYHVGEQWQKEYLG-AICS 2262
             W R  E  G M+ C CLGNGKGE+ C P    C+D   G +Y VGE W+K Y G  +  
Sbjct: 153  TWRRPHETGGYMLECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQGWMMVD 212

Query: 2263 CTCFGGQRG 2271
            CTC G   G
Sbjct: 213  CTCLGEGSG 221



 Score =  115 bits (287), Expect = 7e-25
 Identities = 57/129 (44%), Positives = 74/129 (57%), Gaps = 5/129 (3%)

Query: 94   EETCFDKYTGNTYRVGDTYERPKDSMI-WDCTCIGAGRGRISCTIANRCHEGGQSYKIGD 152
            +++CFD YT + Y VGD +ER  +S     C C+G G G   C  +  CH+ G +YKIG+
Sbjct: 2294 DDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHDNGVNYKIGE 2353

Query: 153  TWRRPHETGGYMLECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQGWMMVD 212
             W R  E  G M+ C CLGNGKGE+ C P    C+D   G +Y VGE W+K Y G  +  
Sbjct: 2354 KWDRQGE-NGQMMSCTCLGNGKGEFKCDPHEATCYDD--GKTYHVGEQWQKEYLG-AICS 2409

Query: 213  CTCLGEGSG 221
            CTC G   G
Sbjct: 2410 CTCFGGQRG 2418



 Score = 98.6 bits (244), Expect = 6e-20
 Identities = 54/172 (31%), Positives = 73/172 (42%), Gaps = 34/172 (19%)

Query: 2130 EVVTVGNSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRC 2189
            E V +GN   E   +P  + CFD    + Y VG+ WE+  +    + C CLG GSG   C
Sbjct: 166  ECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITC 225

Query: 2190 DSSRWCHDNG--VNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPH------------ 2235
             S   C+D     +Y+IG+ W ++   G ++ C C GNG+GE+KC+ H            
Sbjct: 226  TSRNRCNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGP 285

Query: 2236 ----EATCY----------------DDGKTYHVGEQWQKEYLGAICSCTCFG 2267
                 A  Y                D G  Y VG QW K        CTC G
Sbjct: 286  FTDVRAAVYQPQPHPQPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLG 337



 Score = 98.6 bits (244), Expect = 6e-20
 Identities = 54/172 (31%), Positives = 73/172 (42%), Gaps = 34/172 (19%)

Query: 166  ECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITC 225
            E V +GN   E   +P  + CFD    + Y VG+ WE+  +    + C CLG GSG   C
Sbjct: 2277 EVVTVGNSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRC 2336

Query: 226  TSRNRCNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGP 285
             S   C+D     +Y+IG+ W ++   G ++ C C GNG+GE+KC+ H            
Sbjct: 2337 DSSRWCHDNG--VNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPH------------ 2382

Query: 286  FTDVRAAVYQPQPHPQPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLG 337
                 A  Y                D G  Y VG QW K        CTC G
Sbjct: 2383 ----EATCY----------------DDGKTYHVGEQWQKEYLGAICSCTCFG 2414



 Score = 90.9 bits (224), Expect = 1e-17
 Identities = 40/123 (32%), Positives = 65/123 (52%), Gaps = 8/123 (6%)

Query: 2159 YAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHD----NGVNYKIGEKWDRQGEN 2214
            Y +GD+W++  + G  + C C+G G G + C +     D    + + Y + + + ++ E 
Sbjct: 478  YRIGDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEE 537

Query: 2215 GQMMSCTCLGNGKGEFKCDPHEATCYDD--GKTYHVGEQWQKEYLGAICSCTCFG-GQRG 2271
            G M++CTC G G+G +KCDP +  C D   G  Y +G+ W+K   G    C C+G G   
Sbjct: 538  GHMLNCTCFGQGRGRWKCDPVD-QCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGE 596

Query: 2272 WRC 2274
            W C
Sbjct: 597  WHC 599



 Score = 90.9 bits (224), Expect = 1e-17
 Identities = 40/123 (32%), Positives = 65/123 (52%), Gaps = 8/123 (6%)

Query: 478  YRIGDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEE 537
            Y +GD+W++  + G  + C C+G G G + C +     D    + + Y + + + ++ E 
Sbjct: 2306 YAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHD----NGVNYKIGEKWDRQGEN 2361

Query: 538  GHMLNCTCFGQGRGRWKCDPVD-QCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGE 596
            G M++CTC G G+G +KCDP +  C D   G  Y +G+ W+K   G    C C+G G   
Sbjct: 2362 GQMMSCTCLGNGKGEFKCDPHEATCYDD--GKTYHVGEQWQKEYLGAICSCTCFG-GQRG 2418

Query: 597  WHC 599
            W C
Sbjct: 2419 WRC 2421



 Score = 88.2 bits (217), Expect = 9e-17
 Identities = 45/124 (36%), Positives = 65/124 (52%), Gaps = 7/124 (5%)

Query: 2159 YAVGDEWERMSESG-FKLLCQCLGFGSGHFRCDS-SRWCHDN--GVNYKIGEKWDRQGEN 2214
            Y +GD W R  E+G + L C CLG G G + C   +  C D+  G +Y +GE W++  + 
Sbjct: 148  YKIGDTWRRPHETGGYMLECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQG 207

Query: 2215 GQMMSCTCLGNGKGEFKCDPHEATCYDDGKT-YHVGEQW-QKEYLGAICSCTCFGGQRG- 2271
              M+ CTCLG G G   C         D +T Y +G+ W +K+  G +  C C G  RG 
Sbjct: 208  WMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGE 267

Query: 2272 WRCD 2275
            W+C+
Sbjct: 268  WKCE 271



 Score = 88.2 bits (217), Expect = 9e-17
 Identities = 45/124 (36%), Positives = 65/124 (52%), Gaps = 7/124 (5%)

Query: 148  YKIGDTWRRPHETGGYMLECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQG 207
            Y +GD W R  E+G + L C CLG G G + C   +  C D+  G +Y +GE W++  + 
Sbjct: 2306 YAVGDEWERMSESG-FKLLCQCLGFGSGHFRCDS-SRWCHDN--GVNYKIGEKWDRQGEN 2361

Query: 208  WMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGE 267
              M+ CTCLG G G   C         D +T Y +G+ W +K+  G +  C C G  RG 
Sbjct: 2362 GQMMSCTCLGNGKGEFKCDPHEATCYDDGKT-YHVGEQW-QKEYLGAICSCTCFGGQRG- 2418

Query: 268  WKCE 271
            W+C+
Sbjct: 2419 WRCD 2422



 Score = 79.7 bits (195), Expect = 3e-14
 Identities = 37/84 (44%), Positives = 54/84 (64%), Gaps = 5/84 (5%)

Query: 2197 DNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEA---TCYDDGKTYHVGEQWQ 2253
            + GV Y+IG++WD+Q + G MM CTC+GNG+GE+ C  +      C  D  TY+V + + 
Sbjct: 473  NEGVMYRIGDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFH 532

Query: 2254 KEY-LGAICSCTCFGGQRG-WRCD 2275
            K +  G + +CTCFG  RG W+CD
Sbjct: 533  KRHEEGHMLNCTCFGQGRGRWKCD 556



 Score = 79.7 bits (195), Expect = 3e-14
 Identities = 37/84 (44%), Positives = 54/84 (64%), Gaps = 5/84 (5%)

Query: 473  NEGVMYRIGDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFH 532
            + GV Y+IG++WD+Q + G MM CTC+GNG+GE+ C  +      C  D  TY+V + + 
Sbjct: 2344 DNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEA---TCYDDGKTYHVGEQWQ 2400

Query: 533  KRHEEGHMLNCTCFGQGRGRWKCD 556
            K +  G + +CTCFG  RG W+CD
Sbjct: 2401 KEY-LGAICSCTCFGGQRG-WRCD 2422



 Score = 63.5 bits (153), Expect = 2e-09
 Identities = 32/82 (39%), Positives = 46/82 (56%), Gaps = 7/82 (8%)

Query: 2195 CHDNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPH---EATCYD--DGKTYHVG 2249
            C+DNG +Y+I ++W+R    G  + CTC G  +G F C+     E TC+D   G TY VG
Sbjct: 52   CYDNGKHYQINQQWERT-YLGNALVCTCYGGSRG-FNCESKPEAEETCFDKYTGNTYRVG 109

Query: 2250 EQWQKEYLGAICSCTCFGGQRG 2271
            + +++     I  CTC G  RG
Sbjct: 110  DTYERPKDSMIWDCTCIGAGRG 131



 Score = 63.5 bits (153), Expect = 2e-09
 Identities = 32/82 (39%), Positives = 46/82 (56%), Gaps = 7/82 (8%)

Query: 52   CYDNGKHYQINQQWERT-YLGNALVCTCYGGSRG-FNCESKPEAEETCFDKYTGNTYRVG 109
            C+DNG +Y+I ++W+R    G  + CTC G  +G F C+     E TC+D   G TY VG
Sbjct: 2342 CHDNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPH---EATCYD--DGKTYHVG 2396

Query: 110  DTYERPKDSMIWDCTCIGAGRG 131
            + +++     I  CTC G  RG
Sbjct: 2397 EQWQKEYLGAICSCTCFGGQRG 2418



 Score = 62.0 bits (149), Expect = 7e-09
 Identities = 37/107 (34%), Positives = 49/107 (45%), Gaps = 10/107 (9%)

Query: 2134 VGNSVNE----GLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRC 2189
            VGN   E      +Q  D    D  T   Y V D + +  E G  L C C G G G ++C
Sbjct: 499  VGNGRGEWTCIAYSQLRDQCIVDDIT---YNVNDTFHKRHEEGHMLNCTCFGQGRGRWKC 555

Query: 2190 DSSRWCHDN--GVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDP 2234
            D    C D+  G  Y+IG+ W++   +G    C C G G GE+ C P
Sbjct: 556  DPVDQCQDSETGTFYQIGDSWEKY-VHGVRYQCYCYGRGIGEWHCQP 601



 Score = 62.0 bits (149), Expect = 7e-09
 Identities = 37/107 (34%), Positives = 49/107 (45%), Gaps = 10/107 (9%)

Query: 499  VGNGRGEWTCIAYSQLRDQCIVDDIT---YNVNDTFHKRHEEGHMLNCTCFGQGRGRWKC 555
            VGN   E      +Q  D    D  T   Y V D + +  E G  L C C G G G ++C
Sbjct: 2281 VGNSVNE----GLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRC 2336

Query: 556  DPVDQCQDSETGTFYQIGDSWEKY-VHGVRYQCYCYGRGIGEWHCQP 601
            D    C D+  G  Y+IG+ W++   +G    C C G G GE+ C P
Sbjct: 2337 DSSRWCHDN--GVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDP 2381



 Score = 57.8 bits (138), Expect = 1e-07
 Identities = 24/62 (38%), Positives = 35/62 (56%), Gaps = 6/62 (9%)

Query: 2239 CYDDGKTYHVGEQWQKEYLGAICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYS 2298
            CYD+GK Y + +QW++ YLG    CTC+GG RG+ C++      +P  E T    Y   +
Sbjct: 52   CYDNGKHYQINQQWERTYLGNALVCTCYGGSRGFNCES------KPEAEETCFDKYTGNT 105

Query: 2299 QR 2300
             R
Sbjct: 106  YR 107



 Score = 57.8 bits (138), Expect = 1e-07
 Identities = 24/62 (38%), Positives = 35/62 (56%), Gaps = 6/62 (9%)

Query: 52   CYDNGKHYQINQQWERTYLGNALVCTCYGGSRGFNCES------KPEAEETCFDKYTGNT 105
            CYD+GK Y + +QW++ YLG    CTC+GG RG+ C++      +P  E T    Y   +
Sbjct: 2386 CYDDGKTYHVGEQWQKEYLGAICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYS 2445

Query: 106  YR 107
             R
Sbjct: 2446 QR 2447



 Score = 50.1 bits (118), Expect = 3e-05
 Identities = 31/110 (28%), Positives = 42/110 (38%), Gaps = 34/110 (30%)

Query: 2150 CFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDS------------------ 2191
            C D  T + Y +GD W +    G  L C C G G G ++C+                   
Sbjct: 231  CNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVR 290

Query: 2192 ---------------SRWCHDNGVNYKIGEKWDRQGENGQMMSCTCLGNG 2226
                                D+GV Y +G +W +   N QM+ CTCLGNG
Sbjct: 291  AAVYQPQPHPQPPPYGHCVTDSGVVYSVGMQWLKTQGNKQML-CTCLGNG 339



 Score = 50.1 bits (118), Expect = 3e-05
 Identities = 31/110 (28%), Positives = 42/110 (38%), Gaps = 34/110 (30%)

Query: 231  CNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVR 290
            C D  T + Y +GD W +    G  L C C G G G ++C+                   
Sbjct: 2297 CFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDS------------------ 2338

Query: 291  AAVYQPQPHPQPPPYGHCVTDSGVVYSVGMQWLKTQGNKQML-CTCLGNG 339
                                D+GV Y +G +W +   N QM+ CTCLGNG
Sbjct: 2339 ---------------SRWCHDNGVNYKIGEKWDRQGENGQMMSCTCLGNG 2373


>gi|47132551 fibronectin 1 isoform 2 preproprotein [Homo sapiens]
          Length = 2421

 Score = 3008 bits (7798), Expect = 0.0
 Identities = 1514/2135 (70%), Positives = 1655/2135 (77%), Gaps = 74/2135 (3%)

Query: 1    MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ 60
            MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ
Sbjct: 1    MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ 60

Query: 61   INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI 120
            INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI
Sbjct: 61   INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI 120

Query: 121  WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK 180
            WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK
Sbjct: 121  WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK 180

Query: 181  PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY 240
            PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY
Sbjct: 181  PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY 240

Query: 241  RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP 300
            RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP
Sbjct: 241  RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP 300

Query: 301  QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC 360
            QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC
Sbjct: 301  QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC 360

Query: 361  VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC 420
            VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC
Sbjct: 361  VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC 420

Query: 421  HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI 480
            HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI
Sbjct: 421  HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI 480

Query: 481  GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM 540
            GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM
Sbjct: 481  GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM 540

Query: 541  LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ 600
            LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ
Sbjct: 541  LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ 600

Query: 601  PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP 660
            PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP
Sbjct: 601  PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP 660

Query: 661  GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP 720
            GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP
Sbjct: 661  GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP 720

Query: 721  LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL 780
            LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL
Sbjct: 721  LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL 780

Query: 781  LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITG 840
            LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITG
Sbjct: 781  LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITG 840

Query: 841  YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG 900
            YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG
Sbjct: 841  YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG 900

Query: 901  TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT 960
            TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT
Sbjct: 901  TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT 960

Query: 961  FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP 1020
            FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP
Sbjct: 961  FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP 1020

Query: 1021 RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG 1080
            RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG
Sbjct: 1021 RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG 1080

Query: 1081 VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV 1140
            VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV
Sbjct: 1081 VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV 1140

Query: 1141 SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT 1200
            SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT
Sbjct: 1141 SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT 1200

Query: 1201 PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS 1260
            PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS
Sbjct: 1201 PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS 1260

Query: 1261 DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSD 1320
            DTIIP VP  TDL F +I   ++ + W P  S  +  + +          + E  +  S 
Sbjct: 1261 DTIIPEVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIFEDFVDSSV 1320

Query: 1321 NAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIA 1380
                +T L PG +Y +SV ++    ES P    Q+T +  PT + F++I  ++  V W  
Sbjct: 1321 GYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAP 1380

Query: 1381 PRA-TITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPL 1439
            P +  +T + +R+ P        E  +  S N++ LTNL PGTEYVVS+ ++  + ES  
Sbjct: 1381 PPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTP 1440

Query: 1440 LIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGS 1499
            L G+Q T  D P  ++    T  S  + W AP  T+  YRI +     +   +E  VP S
Sbjct: 1441 LRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHS 1500

Query: 1500 KSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSIS 1559
            +++ T++ L PG +Y +++ A+ GR +SP     +     T  D P  ++V      S+ 
Sbjct: 1501 RNSITLTNLTPGTEYVVSIVALNGREESPL----LIGQQSTVSDVPRDLEVVAATPTSLL 1556

Query: 1560 VKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSG 1619
            + W   +  V  YR+T     G  P +  T    ++  TI GL+P V+Y ++VYA    G
Sbjct: 1557 ISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRG 1616

Query: 1620 E----SQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHE 1675
            +    S+P+     T ID+P  +  TDV  +SI + W      V+ YRVT ++P++G   
Sbjct: 1617 DSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVT-TTPKNGPGP 1675

Query: 1676 LFPAPDGEEDT-AELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVT 1734
                  G + T   ++GL+P  EY VSV A +   ESQPL+ T  T I  P  L FT V 
Sbjct: 1676 TKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVD 1735

Query: 1735 PTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPD--SSSVVVSGLMVATKYEVSV 1792
              S+   W  P  Q++ YRV  +  E    + E+  APD    +  + GL   ++Y VSV
Sbjct: 1736 VDSIKIAWESPQGQVSRYRVTYSSPE--DGIHELFPAPDGEEDTAELQGLRPGSEYTVSV 1793

Query: 1793 YALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPAN 1852
             AL D + S+P  G  +T   +  P   + T  T T+++  W      +TG++V   P  
Sbjct: 1794 VALHDDMESQPLIGTQSTA--IPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKE 1851

Query: 1853 GQTPIQR-TIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPV--VIDASTAIDAPSNL 1909
               P++   + PD  S  ++GL   T Y++ +Y L D   S P   V+     +  P   
Sbjct: 1852 KTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRA 1911

Query: 1910 RFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEY 1969
            R    T  ++ +SW+     ITG+ +    P +    +    +P V   TITGL+PGT+Y
Sbjct: 1912 RVTDATETTITISWRTKTETITGFQVD-AVPANGQTPIQRTIKPDVRSYTITGLQPGTDY 1970

Query: 1970 TIYVIALKNNQKSEPLIGRKKTVQKTPFVTHPGYDTGNGIQLPGTSGQQPSVGQQMIFEE 2029
             IY+  L +N +S P++    T    P        T N + +     +    G  + +E+
Sbjct: 1971 KIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEK 2030

Query: 2030 HGFRRTTPPTTATPIRHRPRPYPPNVGQEALSQTTISWAPFQDTSEYIISCHPVGTDEEP 2089
             G    +PP    P   RPRP                                       
Sbjct: 2031 PG----SPPREVVP---RPRP--------------------------------------- 2044

Query: 2090 LQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQR 2124
                     T AT+TGL  G  Y I V ALK+ Q+
Sbjct: 2045 -------GVTEATITGLEPGTEYTIYVIALKNNQK 2072



 Score = 2386 bits (6184), Expect = 0.0
 Identities = 1235/1696 (72%), Positives = 1344/1696 (79%), Gaps = 66/1696 (3%)

Query: 659  IPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPF 718
            +P    S  I  L PG  Y   +  I + G Q +      TT+   P             
Sbjct: 768  LPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAP------------- 814

Query: 719  SPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIP 778
                    +V ++  +S VV W      ++G+R+ Y  S EG   + L+LP TA SV + 
Sbjct: 815  -----PDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTE-LNLPETANSVTLS 868

Query: 779  DLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPD------APPDPTVDQVDDTSIVVRWS 832
            DL PG +Y + +Y + E+ E + ++   +TT         +P D    +V D  + + W+
Sbjct: 869  DLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWT 928

Query: 833  RPQAPITGYRIVYSPSVEGSSTELNLPETANSVT-LSDLQPGVQYNITIYAVEENQESTP 891
             P++ +TGYR+   P          LP + N+   ++ L PGV Y   ++AV   +ES P
Sbjct: 929  PPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKP 988

Query: 892  VVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHG 951
            +  QQ T        + +P +LQFV  TD  V + WTPP + +TGYR+ V      G   
Sbjct: 989  LTAQQTTK-------LDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTV------GLTR 1035

Query: 952  QRLPISRNTFAEVT-----GLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFV 1006
            +  P   N    V+      L P   Y   + A+   +ES   T   TT     +   + 
Sbjct: 1036 RGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYN 1095

Query: 1007 NE-TDSTVLVRWTPPRAQITGYRLTVGLTRRGQ-PRQYNVGPSVSKYPLRNLQPASEYTV 1064
             E T++T+++ WTP  A   G++L V  ++ G+ PR+  V        +  L P  EY  
Sbjct: 1096 TEVTETTIVITWTP--APRIGFKLGVRPSQGGEAPRE--VTSDSGSIVVSGLTPGVEYVY 1151

Query: 1065 SLVAIKGNQE--SPKATGVFTTLQPGSSIPPYNTEVTETTIVIT--W---TPAPRIGFKL 1117
            ++  ++  QE  +P    V T L P +++   + E    T V+T  W   T     G+++
Sbjct: 1152 TIQVLRDGQERDAPIVNKVVTPLSPPTNL---HLEANPDTGVLTVSWERSTTPDITGYRI 1208

Query: 1118 GVRPS---QGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPL 1174
               P+   QG      V +D  S     L+PG+EY  ++  ++D +E   PI + ++  +
Sbjct: 1209 TTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKE-SVPISDTIIPEV 1267

Query: 1175 SPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTF 1234
               T+L      D+ +  + W    +  I GYRIT     G+     E+ V +     T 
Sbjct: 1268 PQLTDLSFVDITDSSI-GLRWTPLNSSTIIGYRITVVAA-GEGIPIFEDFVDSSVGYYTV 1325

Query: 1235 DNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSID 1294
              L PG++Y++SV T+ +  ES P + T   AVPPPTDLRFTNIGPDTMRVTWAPPPSID
Sbjct: 1326 TGLEPGIDYDISVITLINGGESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAPPPSID 1385

Query: 1295 LTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQ 1354
            LTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQ
Sbjct: 1386 LTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQ 1445

Query: 1355 KTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSIT 1414
            KTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSIT
Sbjct: 1446 KTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSIT 1505

Query: 1415 LTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVT 1474
            LTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVT
Sbjct: 1506 LTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVT 1565

Query: 1475 VRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPI 1534
            VRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPI
Sbjct: 1566 VRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPI 1625

Query: 1535 SINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQ 1594
            SINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQ
Sbjct: 1626 SINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQ 1685

Query: 1595 TEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWES 1654
            TEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWES
Sbjct: 1686 TEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWES 1745

Query: 1655 PQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPL 1714
            PQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPL
Sbjct: 1746 PQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPL 1805

Query: 1715 IGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDS 1774
            IGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDS
Sbjct: 1806 IGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDS 1865

Query: 1775 SSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISW 1834
            SSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISW
Sbjct: 1866 SSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISW 1925

Query: 1835 RTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSP 1894
            RTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSP
Sbjct: 1926 RTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSP 1985

Query: 1895 VVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPG 1954
            VVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPG
Sbjct: 1986 VVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPG 2045

Query: 1955 VTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQKTPFVTHPGYDTGNGIQLPGT 2014
            VTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQKTPFVTHPGYDTGNGIQLPGT
Sbjct: 2046 VTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQKTPFVTHPGYDTGNGIQLPGT 2105

Query: 2015 SGQQPSVGQQMIFEEHGFRRTTPPTTATPIRHRPRPYPPNVGQEALSQTTISWAPFQDTS 2074
            SGQQPSVGQQMIFEEHGFRRTTPPTTATPIRHRPRPYPPNVGQEALSQTTISWAPFQDTS
Sbjct: 2106 SGQQPSVGQQMIFEEHGFRRTTPPTTATPIRHRPRPYPPNVGQEALSQTTISWAPFQDTS 2165

Query: 2075 EYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHKVREEVVTV 2134
            EYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHKVREEVVTV
Sbjct: 2166 EYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHKVREEVVTV 2225

Query: 2135 GNSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRW 2194
            GNSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRW
Sbjct: 2226 GNSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRW 2285

Query: 2195 CHDNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEATCYDDGKTYHVGEQWQK 2254
            CHDNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEATCYDDGKTYHVGEQWQK
Sbjct: 2286 CHDNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEATCYDDGKTYHVGEQWQK 2345

Query: 2255 EYLGAICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYSQRYHQRTNTNVNCPIE 2314
            EYLGAICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYSQRYHQRTNTNVNCPIE
Sbjct: 2346 EYLGAICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYSQRYHQRTNTNVNCPIE 2405

Query: 2315 CFMPLDVQADREDSRE 2330
            CFMPLDVQADREDSRE
Sbjct: 2406 CFMPLDVQADREDSRE 2421



 Score =  115 bits (287), Expect = 7e-25
 Identities = 57/129 (44%), Positives = 74/129 (57%), Gaps = 5/129 (3%)

Query: 2147 DDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHDNGVNYKIGE 2206
            +++CFD YT + Y VGD +ER  +S     C C+G G G   C  +  CH+ G +YKIG+
Sbjct: 94   EETCFDKYTGNTYRVGDTYERPKDSMI-WDCTCIGAGRGRISCTIANRCHEGGQSYKIGD 152

Query: 2207 KWDRQGE-NGQMMSCTCLGNGKGEFKCDPHEATCYDD--GKTYHVGEQWQKEYLG-AICS 2262
             W R  E  G M+ C CLGNGKGE+ C P    C+D   G +Y VGE W+K Y G  +  
Sbjct: 153  TWRRPHETGGYMLECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQGWMMVD 212

Query: 2263 CTCFGGQRG 2271
            CTC G   G
Sbjct: 213  CTCLGEGSG 221



 Score =  115 bits (287), Expect = 7e-25
 Identities = 57/129 (44%), Positives = 74/129 (57%), Gaps = 5/129 (3%)

Query: 94   EETCFDKYTGNTYRVGDTYERPKDSMI-WDCTCIGAGRGRISCTIANRCHEGGQSYKIGD 152
            +++CFD YT + Y VGD +ER  +S     C C+G G G   C  +  CH+ G +YKIG+
Sbjct: 2238 DDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHDNGVNYKIGE 2297

Query: 153  TWRRPHETGGYMLECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQGWMMVD 212
             W R  E  G M+ C CLGNGKGE+ C P    C+D   G +Y VGE W+K Y G  +  
Sbjct: 2298 KWDRQGE-NGQMMSCTCLGNGKGEFKCDPHEATCYDD--GKTYHVGEQWQKEYLG-AICS 2353

Query: 213  CTCLGEGSG 221
            CTC G   G
Sbjct: 2354 CTCFGGQRG 2362



 Score = 98.6 bits (244), Expect = 6e-20
 Identities = 54/172 (31%), Positives = 73/172 (42%), Gaps = 34/172 (19%)

Query: 2130 EVVTVGNSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRC 2189
            E V +GN   E   +P  + CFD    + Y VG+ WE+  +    + C CLG GSG   C
Sbjct: 166  ECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITC 225

Query: 2190 DSSRWCHDNG--VNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPH------------ 2235
             S   C+D     +Y+IG+ W ++   G ++ C C GNG+GE+KC+ H            
Sbjct: 226  TSRNRCNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGP 285

Query: 2236 ----EATCY----------------DDGKTYHVGEQWQKEYLGAICSCTCFG 2267
                 A  Y                D G  Y VG QW K        CTC G
Sbjct: 286  FTDVRAAVYQPQPHPQPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLG 337



 Score = 98.6 bits (244), Expect = 6e-20
 Identities = 54/172 (31%), Positives = 73/172 (42%), Gaps = 34/172 (19%)

Query: 166  ECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITC 225
            E V +GN   E   +P  + CFD    + Y VG+ WE+  +    + C CLG GSG   C
Sbjct: 2221 EVVTVGNSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRC 2280

Query: 226  TSRNRCNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGP 285
             S   C+D     +Y+IG+ W ++   G ++ C C GNG+GE+KC+ H            
Sbjct: 2281 DSSRWCHDNG--VNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPH------------ 2326

Query: 286  FTDVRAAVYQPQPHPQPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLG 337
                 A  Y                D G  Y VG QW K        CTC G
Sbjct: 2327 ----EATCY----------------DDGKTYHVGEQWQKEYLGAICSCTCFG 2358



 Score = 90.9 bits (224), Expect = 1e-17
 Identities = 40/123 (32%), Positives = 65/123 (52%), Gaps = 8/123 (6%)

Query: 2159 YAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHD----NGVNYKIGEKWDRQGEN 2214
            Y +GD+W++  + G  + C C+G G G + C +     D    + + Y + + + ++ E 
Sbjct: 478  YRIGDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEE 537

Query: 2215 GQMMSCTCLGNGKGEFKCDPHEATCYDD--GKTYHVGEQWQKEYLGAICSCTCFG-GQRG 2271
            G M++CTC G G+G +KCDP +  C D   G  Y +G+ W+K   G    C C+G G   
Sbjct: 538  GHMLNCTCFGQGRGRWKCDPVD-QCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGE 596

Query: 2272 WRC 2274
            W C
Sbjct: 597  WHC 599



 Score = 90.9 bits (224), Expect = 1e-17
 Identities = 40/123 (32%), Positives = 65/123 (52%), Gaps = 8/123 (6%)

Query: 478  YRIGDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEE 537
            Y +GD+W++  + G  + C C+G G G + C +     D    + + Y + + + ++ E 
Sbjct: 2250 YAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHD----NGVNYKIGEKWDRQGEN 2305

Query: 538  GHMLNCTCFGQGRGRWKCDPVD-QCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGE 596
            G M++CTC G G+G +KCDP +  C D   G  Y +G+ W+K   G    C C+G G   
Sbjct: 2306 GQMMSCTCLGNGKGEFKCDPHEATCYDD--GKTYHVGEQWQKEYLGAICSCTCFG-GQRG 2362

Query: 597  WHC 599
            W C
Sbjct: 2363 WRC 2365



 Score = 88.2 bits (217), Expect = 9e-17
 Identities = 45/124 (36%), Positives = 65/124 (52%), Gaps = 7/124 (5%)

Query: 2159 YAVGDEWERMSESG-FKLLCQCLGFGSGHFRCDS-SRWCHDN--GVNYKIGEKWDRQGEN 2214
            Y +GD W R  E+G + L C CLG G G + C   +  C D+  G +Y +GE W++  + 
Sbjct: 148  YKIGDTWRRPHETGGYMLECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQG 207

Query: 2215 GQMMSCTCLGNGKGEFKCDPHEATCYDDGKT-YHVGEQW-QKEYLGAICSCTCFGGQRG- 2271
              M+ CTCLG G G   C         D +T Y +G+ W +K+  G +  C C G  RG 
Sbjct: 208  WMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGE 267

Query: 2272 WRCD 2275
            W+C+
Sbjct: 268  WKCE 271



 Score = 88.2 bits (217), Expect = 9e-17
 Identities = 45/124 (36%), Positives = 65/124 (52%), Gaps = 7/124 (5%)

Query: 148  YKIGDTWRRPHETGGYMLECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQG 207
            Y +GD W R  E+G + L C CLG G G + C   +  C D+  G +Y +GE W++  + 
Sbjct: 2250 YAVGDEWERMSESG-FKLLCQCLGFGSGHFRCDS-SRWCHDN--GVNYKIGEKWDRQGEN 2305

Query: 208  WMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGE 267
              M+ CTCLG G G   C         D +T Y +G+ W +K+  G +  C C G  RG 
Sbjct: 2306 GQMMSCTCLGNGKGEFKCDPHEATCYDDGKT-YHVGEQW-QKEYLGAICSCTCFGGQRG- 2362

Query: 268  WKCE 271
            W+C+
Sbjct: 2363 WRCD 2366



 Score = 79.7 bits (195), Expect = 3e-14
 Identities = 37/84 (44%), Positives = 54/84 (64%), Gaps = 5/84 (5%)

Query: 2197 DNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEA---TCYDDGKTYHVGEQWQ 2253
            + GV Y+IG++WD+Q + G MM CTC+GNG+GE+ C  +      C  D  TY+V + + 
Sbjct: 473  NEGVMYRIGDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFH 532

Query: 2254 KEY-LGAICSCTCFGGQRG-WRCD 2275
            K +  G + +CTCFG  RG W+CD
Sbjct: 533  KRHEEGHMLNCTCFGQGRGRWKCD 556



 Score = 79.7 bits (195), Expect = 3e-14
 Identities = 37/84 (44%), Positives = 54/84 (64%), Gaps = 5/84 (5%)

Query: 473  NEGVMYRIGDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFH 532
            + GV Y+IG++WD+Q + G MM CTC+GNG+GE+ C  +      C  D  TY+V + + 
Sbjct: 2288 DNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEA---TCYDDGKTYHVGEQWQ 2344

Query: 533  KRHEEGHMLNCTCFGQGRGRWKCD 556
            K +  G + +CTCFG  RG W+CD
Sbjct: 2345 KEY-LGAICSCTCFGGQRG-WRCD 2366



 Score = 63.5 bits (153), Expect = 2e-09
 Identities = 32/82 (39%), Positives = 46/82 (56%), Gaps = 7/82 (8%)

Query: 2195 CHDNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPH---EATCYD--DGKTYHVG 2249
            C+DNG +Y+I ++W+R    G  + CTC G  +G F C+     E TC+D   G TY VG
Sbjct: 52   CYDNGKHYQINQQWERT-YLGNALVCTCYGGSRG-FNCESKPEAEETCFDKYTGNTYRVG 109

Query: 2250 EQWQKEYLGAICSCTCFGGQRG 2271
            + +++     I  CTC G  RG
Sbjct: 110  DTYERPKDSMIWDCTCIGAGRG 131



 Score = 63.5 bits (153), Expect = 2e-09
 Identities = 32/82 (39%), Positives = 46/82 (56%), Gaps = 7/82 (8%)

Query: 52   CYDNGKHYQINQQWERT-YLGNALVCTCYGGSRG-FNCESKPEAEETCFDKYTGNTYRVG 109
            C+DNG +Y+I ++W+R    G  + CTC G  +G F C+     E TC+D   G TY VG
Sbjct: 2286 CHDNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPH---EATCYD--DGKTYHVG 2340

Query: 110  DTYERPKDSMIWDCTCIGAGRG 131
            + +++     I  CTC G  RG
Sbjct: 2341 EQWQKEYLGAICSCTCFGGQRG 2362



 Score = 62.0 bits (149), Expect = 7e-09
 Identities = 37/107 (34%), Positives = 49/107 (45%), Gaps = 10/107 (9%)

Query: 2134 VGNSVNE----GLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRC 2189
            VGN   E      +Q  D    D  T   Y V D + +  E G  L C C G G G ++C
Sbjct: 499  VGNGRGEWTCIAYSQLRDQCIVDDIT---YNVNDTFHKRHEEGHMLNCTCFGQGRGRWKC 555

Query: 2190 DSSRWCHDN--GVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDP 2234
            D    C D+  G  Y+IG+ W++   +G    C C G G GE+ C P
Sbjct: 556  DPVDQCQDSETGTFYQIGDSWEKY-VHGVRYQCYCYGRGIGEWHCQP 601



 Score = 62.0 bits (149), Expect = 7e-09
 Identities = 37/107 (34%), Positives = 49/107 (45%), Gaps = 10/107 (9%)

Query: 499  VGNGRGEWTCIAYSQLRDQCIVDDIT---YNVNDTFHKRHEEGHMLNCTCFGQGRGRWKC 555
            VGN   E      +Q  D    D  T   Y V D + +  E G  L C C G G G ++C
Sbjct: 2225 VGNSVNE----GLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRC 2280

Query: 556  DPVDQCQDSETGTFYQIGDSWEKY-VHGVRYQCYCYGRGIGEWHCQP 601
            D    C D+  G  Y+IG+ W++   +G    C C G G GE+ C P
Sbjct: 2281 DSSRWCHDN--GVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDP 2325



 Score = 57.8 bits (138), Expect = 1e-07
 Identities = 24/62 (38%), Positives = 35/62 (56%), Gaps = 6/62 (9%)

Query: 2239 CYDDGKTYHVGEQWQKEYLGAICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYS 2298
            CYD+GK Y + +QW++ YLG    CTC+GG RG+ C++      +P  E T    Y   +
Sbjct: 52   CYDNGKHYQINQQWERTYLGNALVCTCYGGSRGFNCES------KPEAEETCFDKYTGNT 105

Query: 2299 QR 2300
             R
Sbjct: 106  YR 107



 Score = 57.8 bits (138), Expect = 1e-07
 Identities = 24/62 (38%), Positives = 35/62 (56%), Gaps = 6/62 (9%)

Query: 52   CYDNGKHYQINQQWERTYLGNALVCTCYGGSRGFNCES------KPEAEETCFDKYTGNT 105
            CYD+GK Y + +QW++ YLG    CTC+GG RG+ C++      +P  E T    Y   +
Sbjct: 2330 CYDDGKTYHVGEQWQKEYLGAICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYS 2389

Query: 106  YR 107
             R
Sbjct: 2390 QR 2391



 Score = 50.1 bits (118), Expect = 3e-05
 Identities = 31/110 (28%), Positives = 42/110 (38%), Gaps = 34/110 (30%)

Query: 2150 CFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDS------------------ 2191
            C D  T + Y +GD W +    G  L C C G G G ++C+                   
Sbjct: 231  CNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVR 290

Query: 2192 ---------------SRWCHDNGVNYKIGEKWDRQGENGQMMSCTCLGNG 2226
                                D+GV Y +G +W +   N QM+ CTCLGNG
Sbjct: 291  AAVYQPQPHPQPPPYGHCVTDSGVVYSVGMQWLKTQGNKQML-CTCLGNG 339



 Score = 50.1 bits (118), Expect = 3e-05
 Identities = 31/110 (28%), Positives = 42/110 (38%), Gaps = 34/110 (30%)

Query: 231  CNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVR 290
            C D  T + Y +GD W +    G  L C C G G G ++C+                   
Sbjct: 2241 CFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDS------------------ 2282

Query: 291  AAVYQPQPHPQPPPYGHCVTDSGVVYSVGMQWLKTQGNKQML-CTCLGNG 339
                                D+GV Y +G +W +   N QM+ CTCLGNG
Sbjct: 2283 ---------------SRWCHDNGVNYKIGEKWDRQGENGQMMSCTCLGNG 2317


>gi|47132547 fibronectin 1 isoform 7 preproprotein [Homo sapiens]
          Length = 657

 Score = 1440 bits (3728), Expect = 0.0
 Identities = 647/647 (100%), Positives = 647/647 (100%)

Query: 1   MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ 60
           MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ
Sbjct: 1   MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ 60

Query: 61  INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI 120
           INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI
Sbjct: 61  INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI 120

Query: 121 WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK 180
           WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK
Sbjct: 121 WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK 180

Query: 181 PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY 240
           PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY
Sbjct: 181 PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY 240

Query: 241 RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP 300
           RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP
Sbjct: 241 RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP 300

Query: 301 QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC 360
           QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC
Sbjct: 301 QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC 360

Query: 361 VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC 420
           VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC
Sbjct: 361 VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC 420

Query: 421 HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI 480
           HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI
Sbjct: 421 HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI 480

Query: 481 GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM 540
           GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM
Sbjct: 481 GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM 540

Query: 541 LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ 600
           LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ
Sbjct: 541 LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ 600

Query: 601 PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRP 647
           PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRP
Sbjct: 601 PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRP 647



 Score =  115 bits (287), Expect = 7e-25
 Identities = 57/129 (44%), Positives = 74/129 (57%), Gaps = 5/129 (3%)

Query: 2147 DDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHDNGVNYKIGE 2206
            +++CFD YT + Y VGD +ER  +S     C C+G G G   C  +  CH+ G +YKIG+
Sbjct: 94   EETCFDKYTGNTYRVGDTYERPKDSMI-WDCTCIGAGRGRISCTIANRCHEGGQSYKIGD 152

Query: 2207 KWDRQGE-NGQMMSCTCLGNGKGEFKCDPHEATCYDD--GKTYHVGEQWQKEYLG-AICS 2262
             W R  E  G M+ C CLGNGKGE+ C P    C+D   G +Y VGE W+K Y G  +  
Sbjct: 153  TWRRPHETGGYMLECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQGWMMVD 212

Query: 2263 CTCFGGQRG 2271
            CTC G   G
Sbjct: 213  CTCLGEGSG 221



 Score = 98.6 bits (244), Expect = 6e-20
 Identities = 54/172 (31%), Positives = 73/172 (42%), Gaps = 34/172 (19%)

Query: 2130 EVVTVGNSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRC 2189
            E V +GN   E   +P  + CFD    + Y VG+ WE+  +    + C CLG GSG   C
Sbjct: 166  ECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITC 225

Query: 2190 DSSRWCHDNG--VNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPH------------ 2235
             S   C+D     +Y+IG+ W ++   G ++ C C GNG+GE+KC+ H            
Sbjct: 226  TSRNRCNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGP 285

Query: 2236 ----EATCY----------------DDGKTYHVGEQWQKEYLGAICSCTCFG 2267
                 A  Y                D G  Y VG QW K        CTC G
Sbjct: 286  FTDVRAAVYQPQPHPQPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLG 337



 Score = 90.9 bits (224), Expect = 1e-17
 Identities = 40/123 (32%), Positives = 65/123 (52%), Gaps = 8/123 (6%)

Query: 2159 YAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHD----NGVNYKIGEKWDRQGEN 2214
            Y +GD+W++  + G  + C C+G G G + C +     D    + + Y + + + ++ E 
Sbjct: 478  YRIGDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEE 537

Query: 2215 GQMMSCTCLGNGKGEFKCDPHEATCYDD--GKTYHVGEQWQKEYLGAICSCTCFG-GQRG 2271
            G M++CTC G G+G +KCDP +  C D   G  Y +G+ W+K   G    C C+G G   
Sbjct: 538  GHMLNCTCFGQGRGRWKCDPVD-QCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGE 596

Query: 2272 WRC 2274
            W C
Sbjct: 597  WHC 599



 Score = 88.2 bits (217), Expect = 9e-17
 Identities = 45/124 (36%), Positives = 65/124 (52%), Gaps = 7/124 (5%)

Query: 2159 YAVGDEWERMSESG-FKLLCQCLGFGSGHFRCDS-SRWCHDN--GVNYKIGEKWDRQGEN 2214
            Y +GD W R  E+G + L C CLG G G + C   +  C D+  G +Y +GE W++  + 
Sbjct: 148  YKIGDTWRRPHETGGYMLECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQG 207

Query: 2215 GQMMSCTCLGNGKGEFKCDPHEATCYDDGKT-YHVGEQW-QKEYLGAICSCTCFGGQRG- 2271
              M+ CTCLG G G   C         D +T Y +G+ W +K+  G +  C C G  RG 
Sbjct: 208  WMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGE 267

Query: 2272 WRCD 2275
            W+C+
Sbjct: 268  WKCE 271



 Score = 79.7 bits (195), Expect = 3e-14
 Identities = 37/84 (44%), Positives = 54/84 (64%), Gaps = 5/84 (5%)

Query: 2197 DNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEA---TCYDDGKTYHVGEQWQ 2253
            + GV Y+IG++WD+Q + G MM CTC+GNG+GE+ C  +      C  D  TY+V + + 
Sbjct: 473  NEGVMYRIGDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFH 532

Query: 2254 KEY-LGAICSCTCFGGQRG-WRCD 2275
            K +  G + +CTCFG  RG W+CD
Sbjct: 533  KRHEEGHMLNCTCFGQGRGRWKCD 556



 Score = 63.5 bits (153), Expect = 2e-09
 Identities = 32/82 (39%), Positives = 46/82 (56%), Gaps = 7/82 (8%)

Query: 2195 CHDNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPH---EATCYD--DGKTYHVG 2249
            C+DNG +Y+I ++W+R    G  + CTC G  +G F C+     E TC+D   G TY VG
Sbjct: 52   CYDNGKHYQINQQWERT-YLGNALVCTCYGGSRG-FNCESKPEAEETCFDKYTGNTYRVG 109

Query: 2250 EQWQKEYLGAICSCTCFGGQRG 2271
            + +++     I  CTC G  RG
Sbjct: 110  DTYERPKDSMIWDCTCIGAGRG 131



 Score = 62.0 bits (149), Expect = 7e-09
 Identities = 37/107 (34%), Positives = 49/107 (45%), Gaps = 10/107 (9%)

Query: 2134 VGNSVNE----GLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRC 2189
            VGN   E      +Q  D    D  T   Y V D + +  E G  L C C G G G ++C
Sbjct: 499  VGNGRGEWTCIAYSQLRDQCIVDDIT---YNVNDTFHKRHEEGHMLNCTCFGQGRGRWKC 555

Query: 2190 DSSRWCHDN--GVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDP 2234
            D    C D+  G  Y+IG+ W++   +G    C C G G GE+ C P
Sbjct: 556  DPVDQCQDSETGTFYQIGDSWEKY-VHGVRYQCYCYGRGIGEWHCQP 601



 Score = 57.8 bits (138), Expect = 1e-07
 Identities = 24/62 (38%), Positives = 35/62 (56%), Gaps = 6/62 (9%)

Query: 2239 CYDDGKTYHVGEQWQKEYLGAICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYS 2298
            CYD+GK Y + +QW++ YLG    CTC+GG RG+ C++      +P  E T    Y   +
Sbjct: 52   CYDNGKHYQINQQWERTYLGNALVCTCYGGSRGFNCES------KPEAEETCFDKYTGNT 105

Query: 2299 QR 2300
             R
Sbjct: 106  YR 107



 Score = 50.1 bits (118), Expect = 3e-05
 Identities = 31/110 (28%), Positives = 42/110 (38%), Gaps = 34/110 (30%)

Query: 2150 CFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDS------------------ 2191
            C D  T + Y +GD W +    G  L C C G G G ++C+                   
Sbjct: 231  CNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVR 290

Query: 2192 ---------------SRWCHDNGVNYKIGEKWDRQGENGQMMSCTCLGNG 2226
                                D+GV Y +G +W +   N QM+ CTCLGNG
Sbjct: 291  AAVYQPQPHPQPPPYGHCVTDSGVVYSVGMQWLKTQGNKQML-CTCLGNG 339


>gi|93141047 collagen, type XII, alpha 1 long isoform precursor [Homo
            sapiens]
          Length = 3063

 Score =  383 bits (984), Expect = e-105
 Identities = 357/1428 (25%), Positives = 594/1428 (41%), Gaps = 119/1428 (8%)

Query: 628  IQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQY 687
            + W+   P  + +Y++ + P    G  +E T+ G   +  ++GLK G             
Sbjct: 832  LSWSGA-PGKVKQYLVTYTPVAG-GETQEVTVRGDTTNTVLQGLKEG------------- 876

Query: 688  GHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVT-EITASSFVVSWVSASDT 746
                 T++  + T+       + + GE T      +  + VT +IT +S    W SA   
Sbjct: 877  -----TQYALSVTALYASGAGDALFGEGTTLEERGSPQDLVTKDITDTSIGAYWTSAPGM 931

Query: 747  VSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTS 806
            V G+RV ++   +  +    +LP  A    I +L P  KY ++V+     GE   +   +
Sbjct: 932  VRGYRVSWKSLYDDVDTGEKNLPEDAIHTMIENLQPETKYRISVFATYSSGEGEPLTGDA 991

Query: 807  QTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVT 866
             T          VD+  + ++ V W      +  YR+VY P   G      +P T  S  
Sbjct: 992  TTELSQDSKTLKVDEETENTMRVTWKPAPGKVVNYRVVYRPHGRGKQMVAKVPPTVTSTV 1051

Query: 867  LSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIM 926
            L  LQP   Y+IT+  + +  E       ++ +GT  S    SPR+L+  + T     + 
Sbjct: 1052 LKRLQPQTTYDITVLPIYKMGEGK----LRQGSGTTAS-RFKSPRNLKTSDPTMSSFRVT 1106

Query: 927  WTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRES 986
            W P    V GY+V   P       G+ +    +    +  L  G TY   VF +  G ES
Sbjct: 1107 WEPAPGEVKGYKVTFHPTGDDRRLGELVVGPYDNTVVLEELRAGTTYKVNVFGMFDGGES 1166

Query: 987  KPLTAQQTTKLDAPTNLQFVN---------ETDSTVLV--RWTPPRAQITGYRLTVGLTR 1035
             PL  Q+ T L   T +  ++         E D  +LV   W+  RA     R  +    
Sbjct: 1167 SPLVGQEMTTLSDTTVMPILSSGMECLTRAEADIVLLVDGSWSIGRANFRTVRSFISRI- 1225

Query: 1036 RGQPRQYNVGPSVSKYPLRNLQ--PASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPP 1093
                  +++GP   +  L      P +E+ ++    K +            LQ  +++P 
Sbjct: 1226 ---VEVFDIGPKRVQIALAQYSGDPRTEWQLNAHRDKKS-----------LLQAVANLP- 1270

Query: 1094 YNTEVTETTIVITWTPAPRIGFKLGVRP--------------SQGGEAPREVTSDSG--- 1136
            Y    T T + + +        + G+RP                  EAP +   D G   
Sbjct: 1271 YKGGNTLTGMALNFIRQQNFRTQAGMRPRARKIGVLITDGKSQDDVEAPSKKLKDEGVEL 1330

Query: 1137 -----------SIVVSGLTPGVEYVYTI----QVLRDGQERDAPIVNKVVTP--LSPPTN 1179
                        + +    P   + Y +     + R   +    + N V  P  L  P+N
Sbjct: 1331 FAIGIKNADEVELKMIATDPDDTHAYNVADFESLSRIVDDLTINLCNSVKGPGDLEAPSN 1390

Query: 1180 LHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSP 1239
            L +          VSW    +  +  Y++   P +G  G   E  V   ++S    +L P
Sbjct: 1391 LVISERTHRS-FRVSWT-PPSDSVDRYKVEYYPVSG--GKRQEFYVSRMETSTVLKDLKP 1446

Query: 1240 GLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFL 1299
              EY V+VY+V +D+ S P+  T      P   L   ++GP TM V W P      T ++
Sbjct: 1447 ETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVVSLNIYDVGPTTMHVQWQPVGGA--TGYI 1504

Query: 1300 VRYSPVKNEEDVA--ELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKT- 1356
            + Y PVK+ E     E+ + P+ N + LT+L+P TEY V+V +V     S P+  R+ T 
Sbjct: 1505 LSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEPVTVREVTL 1564

Query: 1357 GLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHH-PEHFSGRPREDRVPHSRNSITL 1415
             L  P  +   D+T ++  V W      +  Y +R+  PE      +E  V  S  S +L
Sbjct: 1565 PLPRPQDLKLRDVTHSTMNVFWEPVPGKVRKYIVRYKTPEE---DVKEVEVDRSETSTSL 1621

Query: 1416 TNLTPGTEYVVSIVALNGREESPLLIGQQSTVS-DVPRDLEVVAATPTSLLISWDAPAVT 1474
             +L   T Y VS+ A++   ESP +  Q++T     P +L++   T      +WD  A  
Sbjct: 1622 KDLFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPAPTNLKITEVTSEGFRGTWDHGASD 1681

Query: 1475 VRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAV----TGRGDSPAS 1530
            V  YRIT+   G +S   E  + G ++T     L P   Y +++ A+    +   D   S
Sbjct: 1682 VSLYRITWAPFG-SSDKMETILNGDENTLVFENLNPNTIYEVSITAIYPDESESDDLIGS 1740

Query: 1531 SKPISINYRTEIDK--PSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTK 1588
             + + I   T+  K  P  +QV +   NS++VKW P+S  V  YR+T  P  G G  +T 
Sbjct: 1741 ERTLPI-LTTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQTT 1799

Query: 1589 TAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTN-IDRPKGLAFTDVDVDS 1647
            T G  Q  + ++ L+P   Y ++V +  P GE   +     T  ++  + L   D    +
Sbjct: 1800 TIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRVYDPSTST 1859

Query: 1648 IKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHD 1707
            + + W+  +G   +Y++ Y+    G  EL P P G  + A L+ L+P + YTV+VV ++ 
Sbjct: 1860 LNVRWDHAEGNPRQYKLFYAPAAGGPEELVPIP-GNTNYAILRNLQPDTSYTVTVVPVYT 1918

Query: 1708 DMESQPLIGTQSTAIPA-PTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMK 1766
            + +      T  T +     +++    TP SL  +W P    +  YRV  +P + T P +
Sbjct: 1919 EGDGGRTSDTGRTLMRGLARNVQVYNPTPNSLDVRWDPAPGPVLQYRVVYSPVDGTRPSE 1978

Query: 1767 EINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDAT 1826
             I +  ++  V +  L+  T Y V++ AL       P+     TL   S PR  RV   T
Sbjct: 1979 SIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGRTLPR-SGPRNLRVFGET 2037

Query: 1827 ETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTI-TGLQPGTDYKIYLYT 1885
              +++++W      +  +++   P  G    + T  P  R+  I   LQP T YKI +  
Sbjct: 2038 TNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVPGRRNNVILQPLQPDTPYKITVIA 2097

Query: 1886 LNDNARSSPVVIDAST-AIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPP 1944
            + ++     +  +  T  +  P N+           VSW P  + + GY I Y+  GS  
Sbjct: 2098 VYEDGDGGHLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPSPVLGYKIVYKPVGS-- 2155

Query: 1945 REVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTV 1992
             E +      +T  T+  L P T Y + V A  ++  S PL  +  T+
Sbjct: 2156 NEPMEAFVGEMTSYTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQGTTL 2203



 Score =  334 bits (856), Expect = 7e-91
 Identities = 325/1304 (24%), Positives = 551/1304 (42%), Gaps = 84/1304 (6%)

Query: 727  SVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKY 786
            S +E+T+  F  +W  A + V  + + Y+ +   DE   ++ P+++TSV +  L P   Y
Sbjct: 639  SFSEVTSYGFKTNWSPAGENVFSYHITYKEAAGDDEVTVVE-PASSTSVVLSSLKPETLY 697

Query: 787  IVNVYQISEDGEQSLILSTSQTT--APDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIV 844
            +VNV    EDG  S+ L+  +TT     AP +  V      S  + W++    +  YRI+
Sbjct: 698  LVNVTAEYEDGF-SIPLAGEETTEEVKGAPRNLKVTDETTDSFKITWTQAPGRVLRYRII 756

Query: 845  YSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRS 904
            Y P   G S E+  P      TL +L P  +Y +++     +   TP+      TG   +
Sbjct: 757  YRPVAGGESREVTTPPNQRRRTLENLIPDTKYEVSVIPEYFSGPGTPL------TGNAAT 810

Query: 905  DTV-PSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAE 963
            + V  +PRDL+  + T   + + W+     V  Y V   PV   G   Q + +  +T   
Sbjct: 811  EEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTYTPV--AGGETQEVTVRGDTTNT 868

Query: 964  V-TGLSPGVTYYFKVFAVSHGRESKPLTAQQTT--KLDAPTNLQFVNETDSTVLVRWTPP 1020
            V  GL  G  Y   V A+        L  + TT  +  +P +L   + TD+++   WT  
Sbjct: 869  VLQGLKEGTQYALSVTALYASGAGDALFGEGTTLEERGSPQDLVTKDITDTSIGAYWTSA 928

Query: 1021 RAQITGYRLT-VGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKAT 1079
               + GYR++   L       + N+        + NLQP ++Y +S+ A   + E    T
Sbjct: 929  PGMVRGYRVSWKSLYDDVDTGEKNLPEDAIHTMIENLQPETKYRISVFATYSSGEGEPLT 988

Query: 1080 GVFTTLQPGSSIPPYNTEVTETTIVITWTPAPR--IGFKLGVRP-SQGGEAPREVTSDSG 1136
            G  TT     S      E TE T+ +TW PAP   + +++  RP  +G +   +V     
Sbjct: 989  GDATTELSQDSKTLKVDEETENTMRVTWKPAPGKVVNYRVVYRPHGRGKQMVAKVPPTVT 1048

Query: 1137 SIVVSGLTPGVEYVYTI-QVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSW 1195
            S V+  L P   Y  T+  + + G+ +         +    P NL   ++P      V+W
Sbjct: 1049 STVLKRLQPQTTYDITVLPIYKMGEGKLRQGSGTTASRFKSPRNLK-TSDPTMSSFRVTW 1107

Query: 1196 ERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKE 1255
            E     ++ GY++T  PT G      E VV    ++   + L  G  Y V+V+ + D  E
Sbjct: 1108 E-PAPGEVKGYKVTFHPT-GDDRRLGELVVGPYDNTVVLEELRAGTTYKVNVFGMFDGGE 1165

Query: 1256 SVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAP-------PPSIDLTNFLVRYSPVKNE 1308
            S P+    +  +   T +   + G + +    A          SI   NF    S +   
Sbjct: 1166 SSPLVGQEMTTLSDTTVMPILSSGMECLTRAEADIVLLVDGSWSIGRANFRTVRSFISRI 1225

Query: 1309 EDVAELSISPSDNAVVLTNLLPGTEYVVSV----SSVYEQHESTPLRGRQKTGLDSPTGI 1364
             +V ++       A+   +  P TE+ ++      S+ +   + P +G      ++ TG+
Sbjct: 1226 VEVFDIGPKRVQIALAQYSGDPRTEWQLNAHRDKKSLLQAVANLPYKGG-----NTLTGM 1280

Query: 1365 DFSDITANSF-TVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTE 1423
              + I   +F T   + PRA   G  I              ++      +    +    E
Sbjct: 1281 ALNFIRQQNFRTQAGMRPRARKIGVLITDGKSQDDVEAPSKKLKDEGVELFAIGIKNADE 1340

Query: 1424 YVVSIVALNGREESPLLIGQQSTVS--------------------DVPRDLEVVAATPTS 1463
              + ++A +  +     +    ++S                    + P +L +   T  S
Sbjct: 1341 VELKMIATDPDDTHAYNVADFESLSRIVDDLTINLCNSVKGPGDLEAPSNLVISERTHRS 1400

Query: 1464 LLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTG 1523
              +SW  P+ +V  Y++ Y    G    QEF V   +++  +  LKP  +Y + VY+V  
Sbjct: 1401 FRVSWTPPSDSVDRYKVEYYPVSGGKR-QEFYVSRMETSTVLKDLKPETEYVVNVYSVV- 1458

Query: 1524 RGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPG 1583
                   S+P+    +T       + + DV   ++ V+W P     TGY ++  P     
Sbjct: 1459 ---EDEYSEPLKGTEKTLPVPVVSLNIYDVGPTTMHVQWQPVGG-ATGYILSYKPVKDTE 1514

Query: 1584 PTKTKTA--GPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVT-NIDRPKGLAF 1640
            PT+ K    GP   +M +  L P  EY V+V A      S+P+    VT  + RP+ L  
Sbjct: 1515 PTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEPVTVREVTLPLPRPQDLKL 1574

Query: 1641 TDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTV 1700
             DV   ++ + WE   G+V +Y V Y +PE+ + E+    D  E +  L+ L   + YTV
Sbjct: 1575 RDVTHSTMNVFWEPVPGKVRKYIVRYKTPEEDVKEV--EVDRSETSTSLKDLFSQTLYTV 1632

Query: 1701 SVVALHDDMESQPLIGTQST-AIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPK 1759
            SV A+HD+ ES P+   ++T  +PAPT+LK T+VT       W      ++ YR+   P 
Sbjct: 1633 SVSAVHDEGESPPVTAQETTRPVPAPTNLKITEVTSEGFRGTWDHGASDVSLYRITWAPF 1692

Query: 1760 EKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYAL-------KDTLTSRPAQGVVTTLE 1812
              +  M+ I L  D +++V   L   T YEVS+ A+        D + S     ++TT  
Sbjct: 1693 GSSDKMETI-LNGDENTLVFENLNPNTIYEVSITAIYPDESESDDLIGSERTLPILTTQA 1751

Query: 1813 NVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQ-RTIKPDVRSYTIT 1871
              S PR  +V +AT  ++T+ W   +  +  +++   P+ G+   Q  TI     S  + 
Sbjct: 1752 PKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQTTTIGGRQNSVVLQ 1811

Query: 1872 GLQPGTDYKIYLYTLNDNARSSPVVIDAST-AIDAPSNLRFLATTPNSLLVSWQPPRARI 1930
             L+P T Y I + +L  +     +     T  ++   NLR    + ++L V W       
Sbjct: 1812 KLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRVYDPSTSTLNVRWDHAEGNP 1871

Query: 1931 TGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVI 1974
              Y + Y      P E+VP P      A +  L+P T YT+ V+
Sbjct: 1872 RQYKLFYAPAAGGPEELVPIP-GNTNYAILRNLQPDTSYTVTVV 1914



 Score =  296 bits (757), Expect = 2e-79
 Identities = 244/929 (26%), Positives = 413/929 (44%), Gaps = 43/929 (4%)

Query: 997  LDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNL 1056
            L+AP+NL     T  +  V WTPP   +  Y++       G+ +++ V    +   L++L
Sbjct: 1385 LEAPSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSGGKRQEFYVSRMETSTVLKDL 1444

Query: 1057 QPASEYTVSLVAIKGNQESPKATGVFTTLQ-PGSSIPPYNTEVTETTIVITWTP-APRIG 1114
            +P +EY V++ ++  ++ S    G   TL  P  S+  Y  +V  TT+ + W P     G
Sbjct: 1445 KPETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVVSLNIY--DVGPTTMHVQWQPVGGATG 1502

Query: 1115 FKLGVRPSQGGEAPREVTSDSGSIV----VSGLTPGVEYVYTIQVLRDGQERDAPIVNKV 1170
            + L  +P +  E  R      G  V    ++ L P  EY  T+Q +      +   V +V
Sbjct: 1503 YILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEPVTVREV 1562

Query: 1171 VTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQS 1230
              PL  P +L L  +     + V WE    P      I    T  +    +E  V   ++
Sbjct: 1563 TLPLPRPQDLKLR-DVTHSTMNVFWE--PVPGKVRKYIVRYKTPEEDVKEVE--VDRSET 1617

Query: 1231 SCTFDNLSPGLEYNVSVYTVKDDKESVPIS--DTIIPAVPPPTDLRFTNIGPDTMRVTWA 1288
            S +  +L     Y VSV  V D+ ES P++  +T  P VP PT+L+ T +  +  R TW 
Sbjct: 1618 STSLKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRP-VPAPTNLKITEVTSEGFRGTWD 1676

Query: 1289 PPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVY-EQHES 1347
               S D++ + + ++P     D  E  ++  +N +V  NL P T Y VS++++Y ++ ES
Sbjct: 1677 HGAS-DVSLYRITWAPF-GSSDKMETILNGDENTLVFENLNPNTIYEVSITAIYPDESES 1734

Query: 1348 TPLRGRQKT--------GLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSG 1399
              L G ++T            P  +   + T+NS TV W      +  YRI + P    G
Sbjct: 1735 DDLIGSERTLPILTTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEG 1794

Query: 1400 RPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVS-DVPRDLEVVA 1458
              +   +   +NS+ L  L P T Y +++ +L    E   + G+  T   +  R+L V  
Sbjct: 1795 NEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRVYD 1854

Query: 1459 ATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITV 1518
             + ++L + WD      R Y++ Y    G  P +   +PG+ + A +  L+P   YT+TV
Sbjct: 1855 PSTSTLNVRWDHAEGNPRQYKLFYAPAAG-GPEELVPIPGNTNYAILRNLQPDTSYTVTV 1913

Query: 1519 YAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTP 1578
              V   GD   +S       R        +QV +   NS+ V+W P+  PV  YRV  +P
Sbjct: 1914 VPVYTEGDGGRTSDTGRTLMR---GLARNVQVYNPTPNSLDVRWDPAPGPVLQYRVVYSP 1970

Query: 1579 KNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPL-VQTAVTNIDRPKG 1637
             +G  P+++     +   + +E L P   Y V++ A    GE  P   Q        P+ 
Sbjct: 1971 VDGTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGRTLPRSGPRN 2030

Query: 1638 LAFTDVDVDSIKIAWESPQGQVSRYRVTYS-SPEDGIHELFPAPDGEEDTAELQGLRPGS 1696
            L       +S+ +AW+   G V +YR+ YS +  D I E    P G  +   LQ L+P +
Sbjct: 2031 LRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVP-GRRNNVILQPLQPDT 2089

Query: 1697 EYTVSVVALHDDMESQPLIGT-QSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVR 1755
             Y ++V+A+++D +   L G  ++  +  P ++  +    T     W P    + GY++ 
Sbjct: 2090 PYKITVIAVYEDGDGGHLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPSPVLGYKIV 2149

Query: 1756 VTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLE-NV 1814
              P     PM+      + +S  +  L  +T Y+V+VYA  D+  S P     TTL  NV
Sbjct: 2150 YKPVGSNEPMEA--FVGEMTSYTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQGTTLYLNV 2207

Query: 1815 SPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQ 1874
            +  +  ++      T  + W +     T +++   PA+G    + T++    S+  TGL 
Sbjct: 2208 TDLKTYQI---GWDTFCVKW-SPHRAATSYRLKLSPADGTRGQEITVRGSETSHCFTGLS 2263

Query: 1875 PGTDYKIYLYTLNDNARSSPVVIDASTAI 1903
            P TDY + ++    N     V +   T +
Sbjct: 2264 PDTDYGVTVFVQTPNLEGPGVSVKEHTTV 2292



 Score =  277 bits (709), Expect = 8e-74
 Identities = 256/949 (26%), Positives = 419/949 (44%), Gaps = 63/949 (6%)

Query: 1087 PGSSIPPYNTEVTETT---IVITWTPAPRI--GFKLGVRPSQGGEAPR-EVTSDSGSIVV 1140
            PG    P N  ++E T     ++WTP       +K+   P  GG+     V+    S V+
Sbjct: 1382 PGDLEAPSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSGGKRQEFYVSRMETSTVL 1441

Query: 1141 SGLTPGVEYVYTI-QVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERST 1199
              L P  EYV  +  V+ D  E   P+     T   P  +L++    D G  T+  +   
Sbjct: 1442 KDLKPETEYVVNVYSVVED--EYSEPLKGTEKTLPVPVVSLNIY---DVGPTTMHVQWQP 1496

Query: 1200 TPDITGYRITTTPTNGQQGNSLEEV-VHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVP 1258
                TGY ++  P    +    +EV +    +     +L P  EY V+V  V  D  S P
Sbjct: 1497 VGGATGYILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEP 1556

Query: 1259 IS--DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSI 1316
            ++  +  +P +P P DL+  ++   TM V W P P   +  ++VRY     EEDV E+ +
Sbjct: 1557 VTVREVTLP-LPRPQDLKLRDVTHSTMNVFWEPVPG-KVRKYIVRYKTP--EEDVKEVEV 1612

Query: 1317 SPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTG-LDSPTGIDFSDITANSFT 1375
              S+ +  L +L   T Y VSVS+V+++ ES P+  ++ T  + +PT +  +++T+  F 
Sbjct: 1613 DRSETSTSLKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPAPTNLKITEVTSEGFR 1672

Query: 1376 VHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGRE 1435
              W    + ++ YRI   P   S +  E  +    N++   NL P T Y VSI A+   E
Sbjct: 1673 GTWDHGASDVSLYRITWAPFGSSDK-METILNGDENTLVFENLNPNTIYEVSITAIYPDE 1731

Query: 1436 -ESPLLIGQQSTVSDV--------PRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETG 1486
             ES  LIG + T+  +        PR+L+V  AT  SL + WD  +  V+ YRITY  + 
Sbjct: 1732 SESDDLIGSERTLPILTTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPST 1791

Query: 1487 GNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVT-----GRGDSPASSKPISINYRTE 1541
            G    Q  T+ G +++  +  LKP   YTITV ++      GR      +KP++      
Sbjct: 1792 GEGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNT----- 1846

Query: 1542 IDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEG 1601
                  ++V D   ++++V+W  +      Y++   P  G GP +      +     +  
Sbjct: 1847 ---VRNLRVYDPSTSTLNVRWDHAEGNPRQYKLFYAPAAG-GPEELVPIPGNTNYAILRN 1902

Query: 1602 LQPTVEY---VVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQ 1658
            LQP   Y   VV VY +   G +    +T +  + R   +   +   +S+ + W+   G 
Sbjct: 1903 LQPDTSYTVTVVPVYTEGDGGRTSDTGRTLMRGLAR--NVQVYNPTPNSLDVRWDPAPGP 1960

Query: 1659 VSRYRVTYSSPEDGIH--ELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIG 1716
            V +YRV YS P DG    E    P G      L+ L P + Y+V++VAL+ D E  P   
Sbjct: 1961 VLQYRVVYS-PVDGTRPSESIVVP-GNTRMVHLERLIPDTLYSVNLVALYSDGEGNPS-P 2017

Query: 1717 TQSTAIP--APTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDS 1774
             Q   +P   P +L+    T  SLS  W   +  +  YR+  +P     P+ E    P  
Sbjct: 2018 AQGRTLPRSGPRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGD-PIDEYTTVPGR 2076

Query: 1775 -SSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITIS 1833
             ++V++  L   T Y+++V A+ +        G   T+  + PP+   ++D   T   +S
Sbjct: 2077 RNNVILQPLQPDTPYKITVIAVYEDGDGGHLTGNGRTV-GLLPPQNIHISDEWYTRFRVS 2135

Query: 1834 WRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSS 1893
            W      + G+++   P     P++  +  ++ SYT+  L P T Y + +Y   D+  S 
Sbjct: 2136 WDPSPSPVLGYKIVYKPVGSNEPMEAFVG-EMTSYTLHNLNPSTTYDVNVYAQYDSGLSV 2194

Query: 1894 PVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRP 1953
            P+    +T     ++L+      ++  V W P RA  T Y +K   P    R      R 
Sbjct: 2195 PLTDQGTTLYLNVTDLKTYQIGWDTFCVKWSPHRA-ATSYRLKL-SPADGTRGQEITVRG 2252

Query: 1954 GVTEATITGLEPGTEYTIYVIALKNNQKSEPL-IGRKKTVQKTPFVTHP 2001
              T    TGL P T+Y + V     N +   + +    TV+ T   T P
Sbjct: 2253 SETSHCFTGLSPDTDYGVTVFVQTPNLEGPGVSVKEHTTVKPTEAPTEP 2301



 Score =  256 bits (655), Expect = 1e-67
 Identities = 254/947 (26%), Positives = 393/947 (41%), Gaps = 51/947 (5%)

Query: 812  DAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQ 871
            +AP +  + +    S  V W+ P   +  Y++ Y P   G   E  +     S  L DL+
Sbjct: 1386 EAPSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSGGKRQEFYVSRMETSTVLKDLK 1445

Query: 872  PGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE 931
            P  +Y + +Y+V E++ S P+       GT ++  VP    L   +V    + + W P  
Sbjct: 1446 PETEYVVNVYSVVEDEYSEPL------KGTEKTLPVPVV-SLNIYDVGPTTMHVQWQPVG 1498

Query: 932  SAVTGYRVDVIPV-----NLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRES 986
             A TGY +   PV       P E   RL  + N   ++T L P   Y   V AV H   S
Sbjct: 1499 GA-TGYILSYKPVKDTEPTRPKE--VRLGPTVNDM-QLTDLVPNTEYAVTVQAVLHDLTS 1554

Query: 987  KPLTAQQTT-KLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVG 1045
            +P+T ++ T  L  P +L+  + T ST+ V W P   ++  Y +    T     ++  V 
Sbjct: 1555 EPVTVREVTLPLPRPQDLKLRDVTHSTMNVFWEPVPGKVRKY-IVRYKTPEEDVKEVEVD 1613

Query: 1046 PSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVI 1105
             S +   L++L   + YTVS+ A+    ESP  T   TT    +      TEVT      
Sbjct: 1614 RSETSTSLKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPAPTNLKITEVTSEGFRG 1673

Query: 1106 TWTPAPRIGFKLGVRPSQGGEAPREVT---SDSGSIVVSGLTPGVEYVYTIQVLRD---- 1158
            TW           +  +  G + +  T    D  ++V   L P   Y  +I  +      
Sbjct: 1674 TWDHGASDVSLYRITWAPFGSSDKMETILNGDENTLVFENLNPNTIYEVSITAIYPDESE 1733

Query: 1159 -----GQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPT 1213
                 G ER  PI+     P S P NL +  N  +  LTV W+   +  +  YRIT  P+
Sbjct: 1734 SDDLIGSERTLPILT-TQAPKSGPRNLQV-YNATSNSLTVKWD-PASGRVQKYRITYQPS 1790

Query: 1214 NGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDT-IIPAVPPPTD 1272
             G +GN     +   Q+S     L P   Y ++V ++  D E   ++       +    +
Sbjct: 1791 TG-EGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVRN 1849

Query: 1273 LRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGT 1332
            LR  +    T+ V W      +   + + Y+P     +   + I  + N  +L NL P T
Sbjct: 1850 LRVYDPSTSTLNVRWDHAEG-NPRQYKLFYAPAAGGPEEL-VPIPGNTNYAILRNLQPDT 1907

Query: 1333 EYVVSVSSVYEQHESTPLRGRQKTGLDS-PTGIDFSDITANSFTVHWIAPRATITGYRIR 1391
             Y V+V  VY + +        +T +      +   + T NS  V W      +  YR+ 
Sbjct: 1908 SYTVTVVPVYTEGDGGRTSDTGRTLMRGLARNVQVYNPTPNSLDVRWDPAPGPVLQYRVV 1967

Query: 1392 HHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVAL-NGREESPLLIGQQSTVSDV 1450
            + P   +       VP +   + L  L P T Y V++VAL +  E +P     ++     
Sbjct: 1968 YSPVDGTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGRTLPRSG 2027

Query: 1451 PRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEF-TVPGSKSTATISGLK 1509
            PR+L V   T  SL ++WD     V+ YRI Y  T G+ P+ E+ TVPG ++   +  L+
Sbjct: 2028 PRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGD-PIDEYTTVPGRRNNVILQPLQ 2086

Query: 1510 PGVDYTITVYAVTGRGDSPASSKPISINYRT-EIDKPSQMQVTDVQDNSISVKWLPSSSP 1568
            P   Y ITV AV   GD       ++ N RT  +  P  + ++D       V W PS SP
Sbjct: 2087 PDTPYKITVIAVYEDGD----GGHLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPSP 2142

Query: 1569 VTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTA 1628
            V GY++   P     P +      + T  T+  L P+  Y V+VYAQ  SG S PL    
Sbjct: 2143 VLGYKIVYKPVGSNEPMEAFVG--EMTSYTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQG 2200

Query: 1629 VTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAE 1688
             T       L    +  D+  + W SP    + YR+   SP DG         G E +  
Sbjct: 2201 TTLYLNVTDLKTYQIGWDTFCVKW-SPHRAATSYRLKL-SPADGTRGQEITVRGSETSHC 2258

Query: 1689 LQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTP 1735
              GL P ++Y V+V     ++E  P +  +      PT+      TP
Sbjct: 2259 FTGLSPDTDYGVTVFVQTPNLEG-PGVSVKEHTTVKPTEAPTEPPTP 2304



 Score =  217 bits (553), Expect = 9e-56
 Identities = 171/613 (27%), Positives = 275/613 (44%), Gaps = 32/613 (5%)

Query: 1266 AVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVL 1325
            A  PP DL F+ +     +  W+P    ++ ++ + Y     +++V  +  + S  +VVL
Sbjct: 631  AYVPPKDLSFSEVTSYGFKTNWSPAGE-NVFSYHITYKEAAGDDEVTVVEPA-SSTSVVL 688

Query: 1326 TNLLPGTEYVVSVSSVYEQHESTPLRGRQKTG--LDSPTGIDFSDITANSFTVHWIAPRA 1383
            ++L P T Y+V+V++ YE   S PL G + T     +P  +  +D T +SF + W     
Sbjct: 689  SSLKPETLYLVNVTAEYEDGFSIPLAGEETTEEVKGAPRNLKVTDETTDSFKITWTQAPG 748

Query: 1384 TITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQ 1443
             +  YRI + P    G  RE   P ++   TL NL P T+Y VS++          L G 
Sbjct: 749  RVLRYRIIYRPVA-GGESREVTTPPNQRRRTLENLIPDTKYEVSVIPEYFSGPGTPLTGN 807

Query: 1444 QST--VSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKS 1501
             +T  V   PRDL V   T +++ +SW      V+ Y +TY    G    QE TV G  +
Sbjct: 808  AATEEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTYTPVAGGE-TQEVTVRGDTT 866

Query: 1502 TATISGLKPGVDYTITVYAV--TGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSIS 1559
               + GLK G  Y ++V A+  +G GD+             E   P  +   D+ D SI 
Sbjct: 867  NTVLQGLKEGTQYALSVTALYASGAGDALFGEGTTL----EERGSPQDLVTKDITDTSIG 922

Query: 1560 VKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSG 1619
              W  +   V GYRV+         T  K    D     IE LQP  +Y +SV+A   SG
Sbjct: 923  AYWTSAPGMVRGYRVSWKSLYDDVDTGEKNLPEDAIHTMIENLQPETKYRISVFATYSSG 982

Query: 1620 ESQPLVQTAVTNIDR-PKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFP 1678
            E +PL   A T + +  K L   +   +++++ W+   G+V  YRV Y     G   +  
Sbjct: 983  EGEPLTGDATTELSQDSKTLKVDEETENTMRVTWKPAPGKVVNYRVVYRPHGRGKQMVAK 1042

Query: 1679 APDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTA--IPAPTDLKFTQVTPT 1736
             P     T  L+ L+P + Y ++V+ ++   E +   G+ +TA    +P +LK +  T +
Sbjct: 1043 VPPTVTSTV-LKRLQPQTTYDITVLPIYKMGEGKLRQGSGTTASRFKSPRNLKTSDPTMS 1101

Query: 1737 SLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALK 1796
            S    W P   ++ GY+V   P      + E+ + P  ++VV+  L   T Y+V+V+ + 
Sbjct: 1102 SFRVTWEPAPGEVKGYKVTFHPTGDDRRLGELVVGPYDNTVVLEELRAGTTYKVNVFGMF 1161

Query: 1797 DTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAV-PANGQT 1855
            D   S P  G               +T  ++TT+     +  E +T  + D V   +G  
Sbjct: 1162 DGGESSPLVG-------------QEMTTLSDTTVMPILSSGMECLTRAEADIVLLVDGSW 1208

Query: 1856 PIQRTIKPDVRSY 1868
             I R     VRS+
Sbjct: 1209 SIGRANFRTVRSF 1221



 Score =  201 bits (510), Expect = 9e-51
 Identities = 157/551 (28%), Positives = 237/551 (43%), Gaps = 20/551 (3%)

Query: 1451 PRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKP 1510
            P+DL     T      +W      V  Y ITY E  G+  V     P S ++  +S LKP
Sbjct: 635  PKDLSFSEVTSYGFKTNWSPAGENVFSYHITYKEAAGDDEVT-VVEPASSTSVVLSSLKP 693

Query: 1511 GVDYTITVYAVTGRGDSPASSKPISINYRTEIDK--PSQMQVTDVQDNSISVKWLPSSSP 1568
               Y + V A    G     S P++    TE  K  P  ++VTD   +S  + W  +   
Sbjct: 694  ETLYLVNVTAEYEDG----FSIPLAGEETTEEVKGAPRNLKVTDETTDSFKITWTQAPGR 749

Query: 1569 VTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTA 1628
            V  YR+   P  G G ++  T  P+Q   T+E L P  +Y VSV  +  SG   PL   A
Sbjct: 750  VLRYRIIYRPVAG-GESREVTTPPNQRRRTLENLIPDTKYEVSVIPEYFSGPGTPLTGNA 808

Query: 1629 VTNIDR--PKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDT 1686
             T   R  P+ L  +D    ++K++W    G+V +Y VTY+ P  G         G+   
Sbjct: 809  ATEEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTYT-PVAGGETQEVTVRGDTTN 867

Query: 1687 AELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIP--APTDLKFTQVTPTSLSAQWTP 1744
              LQGL+ G++Y +SV AL+       L G  +T     +P DL    +T TS+ A WT 
Sbjct: 868  TVLQGLKEGTQYALSVTALYASGAGDALFGEGTTLEERGSPQDLVTKDITDTSIGAYWTS 927

Query: 1745 PNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPA 1804
                + GYRV            E NL  D+   ++  L   TKY +SV+A   +    P 
Sbjct: 928  APGMVRGYRVSWKSLYDDVDTGEKNLPEDAIHTMIENLQPETKYRISVFATYSSGEGEPL 987

Query: 1805 QGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPD 1864
             G  TT E     +  +V + TE T+ ++W+     +  ++V   P      +   + P 
Sbjct: 988  TGDATT-ELSQDSKTLKVDEETENTMRVTWKPAPGKVVNYRVVYRPHGRGKQMVAKVPPT 1046

Query: 1865 VRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTA--IDAPSNLRFLATTPNSLLVS 1922
            V S  +  LQP T Y I +  +             +TA    +P NL+    T +S  V+
Sbjct: 1047 VTSTVLKRLQPQTTYDITVLPIYKMGEGKLRQGSGTTASRFKSPRNLKTSDPTMSSFRVT 1106

Query: 1923 WQPPRARITGYIIKYEKPGSPPR--EVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQ 1980
            W+P    + GY + +   G   R  E+V  P        +  L  GT Y + V  + +  
Sbjct: 1107 WEPAPGEVKGYKVTFHPTGDDRRLGELVVGPYDNTV--VLEELRAGTTYKVNVFGMFDGG 1164

Query: 1981 KSEPLIGRKKT 1991
            +S PL+G++ T
Sbjct: 1165 ESSPLVGQEMT 1175



 Score =  200 bits (508), Expect = 2e-50
 Identities = 217/866 (25%), Positives = 356/866 (41%), Gaps = 75/866 (8%)

Query: 623  PNSHPIQWNAPQP-SHISKYILRWRPKNSVG--RWKEATIPGHLNSYTIKGLKPGVVYEG 679
            P +  +QW   QP    + YIL ++P       R KE  +   +N   +  L P   Y  
Sbjct: 1487 PTTMHVQW---QPVGGATGYILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYA- 1542

Query: 680  QLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSE-SVTEITASSFVV 738
              +++Q   H            TS PVT   VT       PL    +  + ++T S+  V
Sbjct: 1543 --VTVQAVLHD----------LTSEPVTVREVT------LPLPRPQDLKLRDVTHSTMNV 1584

Query: 739  SWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGE 798
             W      V  + V Y+  EE  +   +D   T+TS+   DL     Y V+V  + ++GE
Sbjct: 1585 FWEPVPGKVRKYIVRYKTPEEDVKEVEVDRSETSTSLK--DLFSQTLYTVSVSAVHDEGE 1642

Query: 799  QSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNL 858
               + +   T    AP +  + +V        W    + ++ YRI ++P       E  L
Sbjct: 1643 SPPVTAQETTRPVPAPTNLKITEVTSEGFRGTWDHGASDVSLYRITWAPFGSSDKMETIL 1702

Query: 859  PETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQE------TTGTPRSDTVPSPRD 912
                N++   +L P   Y ++I A+  ++  +  +I  E      TT  P+S     PR+
Sbjct: 1703 NGDENTLVFENLNPNTIYEVSITAIYPDESESDDLIGSERTLPILTTQAPKS----GPRN 1758

Query: 913  LQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVT 972
            LQ    T   +T+ W P    V  YR+   P    G         R     +  L P   
Sbjct: 1759 LQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQTTTIGGRQNSVVLQKLKPDTP 1818

Query: 973  YYFKVFAVSHGRESKPLTAQQTTK-LDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTV 1031
            Y   V ++    E   +T +  TK L+   NL+  + + ST+ VRW         Y+L  
Sbjct: 1819 YTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRVYDPSTSTLNVRWDHAEGNPRQYKLFY 1878

Query: 1032 GLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPG--S 1089
                 G      +  + +   LRNLQP + YTV++V +    +  + +    TL  G   
Sbjct: 1879 APAAGGPEELVPIPGNTNYAILRNLQPDTSYTVTVVPVYTEGDGGRTSDTGRTLMRGLAR 1938

Query: 1090 SIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSG------- 1142
            ++  YN   T  ++ + W PAP    +  V  S     P + T  S SIVV G       
Sbjct: 1939 NVQVYNP--TPNSLDVRWDPAPGPVLQYRVVYS-----PVDGTRPSESIVVPGNTRMVHL 1991

Query: 1143 --LTPGVEY-VYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERST 1199
              L P   Y V  + +  DG+   +P   + + P S P NL +     T  L+V+W+ + 
Sbjct: 1992 ERLIPDTLYSVNLVALYSDGEGNPSPAQGRTL-PRSGPRNLRV-FGETTNSLSVAWDHAD 2049

Query: 1200 TPDITGYRITTTPTNGQQGNSLEE--VVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESV 1257
             P +  YRI  +PT    G+ ++E   V   +++     L P   Y ++V  V +D +  
Sbjct: 2050 GP-VQQYRIIYSPT---VGDPIDEYTTVPGRRNNVILQPLQPDTPYKITVIAVYEDGDGG 2105

Query: 1258 PIS-DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSI 1316
             ++ +     + PP ++  ++      RV+W P PS  +  + + Y PV + E +   + 
Sbjct: 2106 HLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPS-PVLGYKIVYKPVGSNEPME--AF 2162

Query: 1317 SPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTV 1376
                 +  L NL P T Y V+V + Y+   S PL  +  T   + T +    I  ++F V
Sbjct: 2163 VGEMTSYTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQGTTLYLNVTDLKTYQIGWDTFCV 2222

Query: 1377 HWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREE 1436
             W +P    T YR++  P     R +E  V  S  S   T L+P T+Y V++       E
Sbjct: 2223 KW-SPHRAATSYRLKLSPAD-GTRGQEITVRGSETSHCFTGLSPDTDYGVTVFVQTPNLE 2280

Query: 1437 SP-LLIGQQSTVSDVPRDLEVVAATP 1461
             P + + + +TV   P +      TP
Sbjct: 2281 GPGVSVKEHTTVK--PTEAPTEPPTP 2304



 Score =  194 bits (492), Expect = 1e-48
 Identities = 209/874 (23%), Positives = 361/874 (41%), Gaps = 76/874 (8%)

Query: 905  DTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPIS-RNTFAE 963
            + V  P +L  +EV+   V + W P  S VTGY+V + P+   G     L +  + T   
Sbjct: 332  EVVEPPSNLIAMEVSSKYVKLNWNPSPSPVTGYKVILTPMT-AGSRQHALSVGPQTTTLS 390

Query: 964  VTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTK-----------LDAPTNLQF-VNETDS 1011
            V  LS    Y   V A+     S+P++  + T+           +D   ++ F V+ + S
Sbjct: 391  VRDLSADTEYQISVSAMKGMTSSEPISIMEKTQPMKVQVECSRGVDIKADIVFLVDGSYS 450

Query: 1012 TVLVRWTPPRA---------QITGYRLTVGL-----------TRRGQPRQYNVGPSVSKY 1051
              +  +   RA         +I+  R+ + L           T +   +  ++  +++ +
Sbjct: 451  IGIANFVKVRAFLEVLVKSFEISPNRVQISLVQYSRDPHTEFTLKKFTKVEDIIEAINTF 510

Query: 1052 PLR----NLQPASEYTVSLVAI--KGNQES-PKATGVFTTLQPGSSIPPYNTEVTETTIV 1104
            P R    N   A  Y    + +  KG++ + PK   + T  +   +      ++  + + 
Sbjct: 511  PYRGGSTNTGKAMTYVREKIFVPSKGSRSNVPKVMILITDGKSSDAFRDPAIKLRNSDVE 570

Query: 1105 ITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDA 1164
            I       +G K  VR      A     +   ++        + +  T  +    ++  A
Sbjct: 571  IF-----AVGVKDAVRSELEAIASPPAETHVFTVEDFDAFQRISFELTQSICLRIEQELA 625

Query: 1165 PIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEV 1224
             I  K   P   P +L        G  T +W      ++  Y IT     G   + +  V
Sbjct: 626  AIKKKAYVP---PKDLSFSEVTSYGFKT-NWS-PAGENVFSYHITYKEAAGD--DEVTVV 678

Query: 1225 VHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS--DTIIPAVPPPTDLRFTNIGPDT 1282
              A  +S    +L P   Y V+V    +D  S+P++  +T       P +L+ T+   D+
Sbjct: 679  EPASSTSVVLSSLKPETLYLVNVTAEYEDGFSIPLAGEETTEEVKGAPRNLKVTDETTDS 738

Query: 1283 MRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVY 1342
             ++TW   P   +  + + Y PV   E   E++  P+     L NL+P T+Y VSV   Y
Sbjct: 739  FKITWTQAPG-RVLRYRIIYRPVAGGES-REVTTPPNQRRRTLENLIPDTKYEVSVIPEY 796

Query: 1343 EQHESTPLRGRQKTG--LDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGR 1400
                 TPL G   T     +P  +  SD T ++  + W      +  Y + + P    G 
Sbjct: 797  FSGPGTPLTGNAATEEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTYTPV-AGGE 855

Query: 1401 PREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSD--VPRDLEVVA 1458
             +E  V     +  L  L  GT+Y +S+ AL        L G+ +T+ +   P+DL    
Sbjct: 856  TQEVTVRGDTTNTVLQGLKEGTQYALSVTALYASGAGDALFGEGTTLEERGSPQDLVTKD 915

Query: 1459 ATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITV 1518
             T TS+   W +    VR YR+++     +    E  +P       I  L+P   Y I+V
Sbjct: 916  ITDTSIGAYWTSAPGMVRGYRVSWKSLYDDVDTGEKNLPEDAIHTMIENLQPETKYRISV 975

Query: 1519 YAVTGRGDSPASSKPISINYRTEIDKPSQ-MQVTDVQDNSISVKWLPSSSPVTGYRVTTT 1577
            +A    G+     +P++ +  TE+ + S+ ++V +  +N++ V W P+   V  YRV   
Sbjct: 976  FATYSSGE----GEPLTGDATTELSQDSKTLKVDEETENTMRVTWKPAPGKVVNYRVVYR 1031

Query: 1578 PKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDR--- 1634
            P +G G        P  T   ++ LQP   Y ++V      GE + L Q + T   R   
Sbjct: 1032 P-HGRGKQMVAKVPPTVTSTVLKRLQPQTTYDITVLPIYKMGEGK-LRQGSGTTASRFKS 1089

Query: 1635 PKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDG--IHELFPAPDGEEDTAELQGL 1692
            P+ L  +D  + S ++ WE   G+V  Y+VT+    D   + EL   P   ++T  L+ L
Sbjct: 1090 PRNLKTSDPTMSSFRVTWEPAPGEVKGYKVTFHPTGDDRRLGELVVGP--YDNTVVLEEL 1147

Query: 1693 RPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPT 1726
            R G+ Y V+V  + D  ES PL+G + T +   T
Sbjct: 1148 RAGTTYKVNVFGMFDGGESSPLVGQEMTTLSDTT 1181



 Score =  173 bits (438), Expect = 2e-42
 Identities = 209/923 (22%), Positives = 360/923 (39%), Gaps = 128/923 (13%)

Query: 1267 VPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLT 1326
            V PP++L    +    +++ W P PS  +T + V  +P+        LS+ P    + + 
Sbjct: 334  VEPPSNLIAMEVSSKYVKLNWNPSPS-PVTGYKVILTPMTAGSRQHALSVGPQTTTLSVR 392

Query: 1327 NLLPGTEYVVSVSSVYEQHESTPLRGRQKT-----------GLDSPTGIDFSDITANSFT 1375
            +L   TEY +SVS++     S P+   +KT           G+D    I F  +   S++
Sbjct: 393  DLSADTEYQISVSAMKGMTSSEPISIMEKTQPMKVQVECSRGVDIKADIVF--LVDGSYS 450

Query: 1376 V---HWIAPRA----TITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSI 1428
            +   +++  RA     +  + I  +    S   +  R PH+    TL   T   + + +I
Sbjct: 451  IGIANFVKVRAFLEVLVKSFEISPNRVQIS-LVQYSRDPHT--EFTLKKFTKVEDIIEAI 507

Query: 1429 VALNGREES------------PLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVR 1476
                 R  S             + +  + + S+VP+ + ++    +S   ++  PA+ +R
Sbjct: 508  NTFPYRGGSTNTGKAMTYVREKIFVPSKGSRSNVPKVMILITDGKSS--DAFRDPAIKLR 565

Query: 1477 YYRITYGETGGNSPVQEFTV---PGSKSTATISGLKPGVDYTITVYAVTG-RGDSPASSK 1532
                       NS V+ F V      +S        P   +  TV      +  S   ++
Sbjct: 566  -----------NSDVEIFAVGVKDAVRSELEAIASPPAETHVFTVEDFDAFQRISFELTQ 614

Query: 1533 PISINYRTEID--------KPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGP 1584
             I +    E+          P  +  ++V        W P+   V  Y +T   K   G 
Sbjct: 615  SICLRIEQELAAIKKKAYVPPKDLSFSEVTSYGFKTNWSPAGENVFSYHITY--KEAAGD 672

Query: 1585 TKTKTAGP-DQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDR--PKGLAFT 1641
             +     P   T + +  L+P   Y+V+V A+   G S PL     T   +  P+ L  T
Sbjct: 673  DEVTVVEPASSTSVVLSSLKPETLYLVNVTAEYEDGFSIPLAGEETTEEVKGAPRNLKVT 732

Query: 1642 DVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVS 1701
            D   DS KI W    G+V RYR+ Y     G       P  +     L+ L P ++Y VS
Sbjct: 733  DETTDSFKITWTQAPGRVLRYRIIYRPVAGGESREVTTPPNQR-RRTLENLIPDTKYEVS 791

Query: 1702 VVALHDDMESQPLIGTQST--AIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPK 1759
            V+  +      PL G  +T      P DL+ +  T +++   W+    ++  Y V  TP 
Sbjct: 792  VIPEYFSGPGTPLTGNAATEEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTYTP- 850

Query: 1760 EKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRR 1819
               G  +E+ +  D+++ V+ GL   T+Y +SV AL  +       G  TTLE    P+ 
Sbjct: 851  VAGGETQEVTVRGDTTNTVLQGLKEGTQYALSVTALYASGAGDALFGEGTTLEERGSPQD 910

Query: 1820 ARVTDATETTITISWRTKTETITGFQVDAVPANGQTPI-QRTIKPDVRSYTITGLQPGTD 1878
                D T+T+I   W +    + G++V            ++ +  D     I  LQP T 
Sbjct: 911  LVTKDITDTSIGAYWTSAPGMVRGYRVSWKSLYDDVDTGEKNLPEDAIHTMIENLQPETK 970

Query: 1879 YKIYLYTLNDNARSSPVVIDASTAIDAPS-NLRFLATTPNSLLVSWQPPRARITGYIIKY 1937
            Y+I ++    +    P+  DA+T +   S  L+    T N++ V+W+P   ++  Y + Y
Sbjct: 971  YRISVFATYSSGEGEPLTGDATTELSQDSKTLKVDEETENTMRVTWKPAPGKVVNYRVVY 1030

Query: 1938 EKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQKTPF 1997
             +P    +++V +  P VT   +  L+P T Y I V+                       
Sbjct: 1031 -RPHGRGKQMVAKVPPTVTSTVLKRLQPQTTYDITVL----------------------- 1066

Query: 1998 VTHPGYDTGNGIQLPGTSGQQPSVGQQMIFEEHGFRRTTPPTTATPIRHRPRPYPPNVGQ 2057
               P Y  G G +L   SG   S      F+     +T+ PT                  
Sbjct: 1067 ---PIYKMGEG-KLRQGSGTTAS-----RFKSPRNLKTSDPT------------------ 1099

Query: 2058 EALSQTTISWAPFQ-DTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIV 2116
              +S   ++W P   +   Y ++ HP G D    +  V     +  L  L  G TY + V
Sbjct: 1100 --MSSFRVTWEPAPGEVKGYKVTFHPTGDDRRLGELVVGPYDNTVVLEELRAGTTYKVNV 1157

Query: 2117 EALKD--QQRHKVREEVVTVGNS 2137
              + D  +    V +E+ T+ ++
Sbjct: 1158 FGMFDGGESSPLVGQEMTTLSDT 1180



 Score =  161 bits (407), Expect = 8e-39
 Identities = 155/582 (26%), Positives = 252/582 (43%), Gaps = 30/582 (5%)

Query: 885  ENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPV 944
            E  +S  + I+QE     +   VP P+DL F EVT       W+P    V  Y +     
Sbjct: 611  ELTQSICLRIEQELAAIKKKAYVP-PKDLSFSEVTSYGFKTNWSPAGENVFSYHITYKEA 669

Query: 945  NLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTK--LDAPTN 1002
                E     P S +T   ++ L P   Y   V A      S PL  ++TT+    AP N
Sbjct: 670  AGDDEVTVVEPAS-STSVVLSSLKPETLYLVNVTAEYEDGFSIPLAGEETTEEVKGAPRN 728

Query: 1003 LQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEY 1062
            L+  +ET  +  + WT    ++  YR+       G+ R+    P+  +  L NL P ++Y
Sbjct: 729  LKVTDETTDSFKITWTQAPGRVLRYRIIYRPVAGGESREVTTPPNQRRRTLENLIPDTKY 788

Query: 1063 TVSLVAIKGNQESPKATGVFTTLQ-PGSSIPPYNTEVTETTIVITWTPAPR--IGFKLGV 1119
             VS++    +      TG   T +  G+      ++ T +T+ ++W+ AP     + +  
Sbjct: 789  EVSVIPEYFSGPGTPLTGNAATEEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTY 848

Query: 1120 RPSQGGEAPREVT--SDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPI-VNKVVTPLSP 1176
             P  GGE  +EVT   D+ + V+ GL  G +Y  ++  L      DA       +     
Sbjct: 849  TPVAGGET-QEVTVRGDTTNTVLQGLKEGTQYALSVTALYASGAGDALFGEGTTLEERGS 907

Query: 1177 PTNLHLEANPDTGVLTVSWERSTTPDITGYRIT----TTPTNGQQGNSLEEVVHADQSSC 1232
            P +L  +   DT +   ++  S    + GYR++        +  + N  E+ +H      
Sbjct: 908  PQDLVTKDITDTSI--GAYWTSAPGMVRGYRVSWKSLYDDVDTGEKNLPEDAIHT----- 960

Query: 1233 TFDNLSPGLEYNVSVYTVKDDKESVPIS-DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPP 1291
              +NL P  +Y +SV+      E  P++ D           L+      +TMRVTW P P
Sbjct: 961  MIENLQPETKYRISVFATYSSGEGEPLTGDATTELSQDSKTLKVDEETENTMRVTWKPAP 1020

Query: 1292 SIDLTNFLVRYSP-VKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPL 1350
               + N+ V Y P  + ++ VA+  + P+  + VL  L P T Y ++V  +Y+  E    
Sbjct: 1021 G-KVVNYRVVYRPHGRGKQMVAK--VPPTVTSTVLKRLQPQTTYDITVLPIYKMGEGKLR 1077

Query: 1351 RGRQKTG--LDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPH 1408
            +G   T     SP  +  SD T +SF V W      + GY++  HP     R  E  V  
Sbjct: 1078 QGSGTTASRFKSPRNLKTSDPTMSSFRVTWEPAPGEVKGYKVTFHPTGDDRRLGELVVGP 1137

Query: 1409 SRNSITLTNLTPGTEYVVSIVAL-NGREESPLLIGQQSTVSD 1449
              N++ L  L  GT Y V++  + +G E SPL+  + +T+SD
Sbjct: 1138 YDNTVVLEELRAGTTYKVNVFGMFDGGESSPLVGQEMTTLSD 1179



 Score =  155 bits (391), Expect = 6e-37
 Identities = 153/655 (23%), Positives = 255/655 (38%), Gaps = 48/655 (7%)

Query: 636  SHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRF 695
            S +S Y + W P  S  +  E  + G  N+   + L P  +YE   +SI      E    
Sbjct: 1680 SDVSLYRITWAPFGSSDKM-ETILNGDENTLVFENLNPNTIYE---VSITAIYPDESESD 1735

Query: 696  DFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYE 755
            D   +  + P+        TT        +  V   T++S  V W  AS  V  +R+ Y+
Sbjct: 1736 DLIGSERTLPIL-------TTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQ 1788

Query: 756  LSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPP 815
             S      Q   +     SV +  L P   Y + V  +  DGE   +    +T   +   
Sbjct: 1789 PSTGEGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVR 1848

Query: 816  DPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQ 875
            +  V     +++ VRW   +     Y++ Y+P+  G    + +P   N   L +LQP   
Sbjct: 1849 NLRVYDPSTSTLNVRWDHAEGNPRQYKLFYAPAAGGPEELVPIPGNTNYAILRNLQPDTS 1908

Query: 876  YNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVT 935
            Y +T+  V    +         T+ T R+      R++Q    T   + + W P    V 
Sbjct: 1909 YTVTVVPVYTEGDG------GRTSDTGRTLMRGLARNVQVYNPTPNSLDVRWDPAPGPVL 1962

Query: 936  GYRVDVIPVNLPGEHGQRLPISRNT-FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQ-Q 993
             YRV   PV+      + + +  NT    +  L P   Y   + A+    E  P  AQ +
Sbjct: 1963 QYRVVYSPVD-GTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGR 2021

Query: 994  TTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPS-VSKYP 1052
            T     P NL+   ET +++ V W      +  YR+    T      +Y   P   +   
Sbjct: 2022 TLPRSGPRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVPGRRNNVI 2081

Query: 1053 LRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTE---TTIVITW-- 1107
            L+ LQP + Y ++++A+  + +    TG   T+     +PP N  +++   T   ++W  
Sbjct: 2082 LQPLQPDTPYKITVIAVYEDGDGGHLTGNGRTV---GLLPPQNIHISDEWYTRFRVSWDP 2138

Query: 1108 TPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIV 1167
            +P+P +G+K+  +P    E       +  S  +  L P   Y   +    D      P+ 
Sbjct: 2139 SPSPVLGYKIVYKPVGSNEPMEAFVGEMTSYTLHNLNPSTTYDVNVYAQYD-SGLSVPLT 2197

Query: 1168 NKVVTPLSPPTNLH-LEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVH 1226
            ++  T     T+L   +   DT    V W  S     T YR+  +P +G +G   E  V 
Sbjct: 2198 DQGTTLYLNVTDLKTYQIGWDT--FCVKW--SPHRAATSYRLKLSPADGTRGQ--EITVR 2251

Query: 1227 ADQSSCTFDNLSPGLEYNVSVY-----------TVKDDKESVPISDTIIPAVPPP 1270
              ++S  F  LSP  +Y V+V+           +VK+     P      P  PPP
Sbjct: 2252 GSETSHCFTGLSPDTDYGVTVFVQTPNLEGPGVSVKEHTTVKPTEAPTEPPTPPP 2306



 Score =  147 bits (370), Expect = 2e-34
 Identities = 135/576 (23%), Positives = 230/576 (39%), Gaps = 26/576 (4%)

Query: 798  EQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELN 857
            EQ L     +   P  P D +  +V        WS     +  Y I Y  +       + 
Sbjct: 621  EQELAAIKKKAYVP--PKDLSFSEVTSYGFKTNWSPAGENVFSYHITYKEAAGDDEVTVV 678

Query: 858  LPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVE 917
             P ++ SV LS L+P   Y + + A  E+  S P+  ++ T      +   +PR+L+  +
Sbjct: 679  EPASSTSVVLSSLKPETLYLVNVTAEYEDGFSIPLAGEETT-----EEVKGAPRNLKVTD 733

Query: 918  VTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKV 977
             T     I WT     V  YR+   PV   GE  +           +  L P   Y   V
Sbjct: 734  ETTDSFKITWTQAPGRVLRYRIIYRPV-AGGESREVTTPPNQRRRTLENLIPDTKYEVSV 792

Query: 978  FAVSHGRESKPLTAQQTTK--LDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTR 1035
                      PLT    T+     P +L+  + T ST+ + W+    ++  Y +T     
Sbjct: 793  IPEYFSGPGTPLTGNAATEEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTYTPVA 852

Query: 1036 RGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQP-GSSIPPY 1094
             G+ ++  V    +   L+ L+  ++Y +S+ A+  +       G  TTL+  GS     
Sbjct: 853  GGETQEVTVRGDTTNTVLQGLKEGTQYALSVTALYASGAGDALFGEGTTLEERGSPQDLV 912

Query: 1095 NTEVTETTIVITWTPAP------RIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVE 1148
              ++T+T+I   WT AP      R+ +K        GE  + +  D+   ++  L P  +
Sbjct: 913  TKDITDTSIGAYWTSAPGMVRGYRVSWKSLYDDVDTGE--KNLPEDAIHTMIENLQPETK 970

Query: 1149 YVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRI 1208
            Y  ++       E + P+     T LS  +            + V+W +     +  YR+
Sbjct: 971  YRISVFATYSSGEGE-PLTGDATTELSQDSKTLKVDEETENTMRVTW-KPAPGKVVNYRV 1028

Query: 1209 TTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESV--PISDTIIPA 1266
               P    +G  +   V    +S     L P   Y+++V  +    E      S T    
Sbjct: 1029 VYRPHG--RGKQMVAKVPPTVTSTVLKRLQPQTTYDITVLPIYKMGEGKLRQGSGTTASR 1086

Query: 1267 VPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLT 1326
               P +L+ ++    + RVTW P P  ++  + V + P  ++  + EL + P DN VVL 
Sbjct: 1087 FKSPRNLKTSDPTMSSFRVTWEPAPG-EVKGYKVTFHPTGDDRRLGELVVGPYDNTVVLE 1145

Query: 1327 NLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPT 1362
             L  GT Y V+V  +++  ES+PL G++ T L   T
Sbjct: 1146 ELRAGTTYKVNVFGMFDGGESSPLVGQEMTTLSDTT 1181



 Score =  105 bits (263), Expect = 4e-22
 Identities = 119/490 (24%), Positives = 188/490 (38%), Gaps = 49/490 (10%)

Query: 1712 QPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLA 1771
            Q L   +  A   P DL F++VT       W+P    +  Y   +T KE  G  +   + 
Sbjct: 622  QELAAIKKKAYVPPKDLSFSEVTSYGFKTNWSPAGENVFSY--HITYKEAAGDDEVTVVE 679

Query: 1772 PDSS-SVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTI 1830
            P SS SVV+S L   T Y V+V A  +   S P  G  TT E    PR  +VTD T  + 
Sbjct: 680  PASSTSVVLSSLKPETLYLVNVTAEYEDGFSIPLAGEETTEEVKGAPRNLKVTDETTDSF 739

Query: 1831 TISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNA 1890
             I+W      +  +++   P  G    + T  P+ R  T+  L P T Y++ +     + 
Sbjct: 740  KITWTQAPGRVLRYRIIYRPVAGGESREVTTPPNQRRRTLENLIPDTKYEVSVIPEYFSG 799

Query: 1891 RSSPVVIDAST--AIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEK-PGSPPREV 1947
              +P+  +A+T      P +LR    T +++ +SW     ++  Y++ Y    G   +EV
Sbjct: 800  PGTPLTGNAATEEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTYTPVAGGETQEV 859

Query: 1948 VPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQK----TPFVTHPGY 2003
                R   T   + GL+ GT+Y + V AL  +   + L G   T+++       VT    
Sbjct: 860  T--VRGDTTNTVLQGLKEGTQYALSVTALYASGAGDALFGEGTTLEERGSPQDLVTKDIT 917

Query: 2004 DTGNGIQLPGTSG-------------QQPSVGQQMIFEE--HGFRRTTPPTT-------A 2041
            DT  G       G                  G++ + E+  H       P T       A
Sbjct: 918  DTSIGAYWTSAPGMVRGYRVSWKSLYDDVDTGEKNLPEDAIHTMIENLQPETKYRISVFA 977

Query: 2042 TPIRHRPRPYPPN-------------VGQEALSQTTISWAPFQ-DTSEYIISCHPVGTDE 2087
            T       P   +             V +E  +   ++W P       Y +   P G  +
Sbjct: 978  TYSSGEGEPLTGDATTELSQDSKTLKVDEETENTMRVTWKPAPGKVVNYRVVYRPHGRGK 1037

Query: 2088 EPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHKVREEVVTVGNSVNEGLNQPTD 2147
            + +  +VP T TS  L  L    TY+I V  +      K+R+   T  +      N  T 
Sbjct: 1038 Q-MVAKVPPTVTSTVLKRLQPQTTYDITVLPIYKMGEGKLRQGSGTTASRFKSPRNLKTS 1096

Query: 2148 DSCFDPYTVS 2157
            D     + V+
Sbjct: 1097 DPTMSSFRVT 1106



 Score = 66.6 bits (161), Expect = 3e-10
 Identities = 37/123 (30%), Positives = 64/123 (52%), Gaps = 4/123 (3%)

Query: 800 SLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLP 859
           +L+LS+ +    D P D     +D+ ++ + W++P  PI GYRI   P+ +G + E  L 
Sbjct: 15  ALLLSSIEAEV-DPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTTDGPTKEFTLS 73

Query: 860 ETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQ---QETTGTPRSDTVPSPRDLQFV 916
            +     LS+L P  +Y +TI + +E +ES PV+ Q   Q  + T   +  P   ++Q  
Sbjct: 74  ASTTETLLSELVPETEYVVTITSYDEVEESVPVIGQLTIQTGSSTKPVEKKPGKTEIQKC 133

Query: 917 EVT 919
            V+
Sbjct: 134 SVS 136



 Score = 59.7 bits (143), Expect = 3e-08
 Identities = 28/85 (32%), Positives = 44/85 (51%), Gaps = 1/85 (1%)

Query: 1541 EIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIE 1600
            E+D PS +    + +N++ + W     P+ GYR+T  P    GPTK  T     TE  + 
Sbjct: 24   EVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTT-DGPTKEFTLSASTTETLLS 82

Query: 1601 GLQPTVEYVVSVYAQNPSGESQPLV 1625
             L P  EYVV++ + +   ES P++
Sbjct: 83   ELVPETEYVVTITSYDEVEESVPVI 107



 Score = 58.9 bits (141), Expect = 6e-08
 Identities = 37/117 (31%), Positives = 59/117 (50%), Gaps = 5/117 (4%)

Query: 996  KLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRN 1055
            ++D P++L F    ++TV + W  P   I GYR+TV  T  G  +++ +  S ++  L  
Sbjct: 24   EVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTTDGPTKEFTLSASTTETLLSE 83

Query: 1056 LQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTI----VITWT 1108
            L P +EY V++ +    +ES    G   T+Q GSS  P   +  +T I    V  WT
Sbjct: 84   LVPETEYVVTITSYDEVEESVPVIGQL-TIQTGSSTKPVEKKPGKTEIQKCSVSAWT 139



 Score = 53.5 bits (127), Expect = 2e-06
 Identities = 29/87 (33%), Positives = 48/87 (55%), Gaps = 2/87 (2%)

Query: 1267 VPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLT 1326
            V PP+DL F  I  +T+ ++WA P    +  + +   P   +    E ++S S    +L+
Sbjct: 25   VDPPSDLNFKIIDENTVHMSWAKPVD-PIVGYRITVDPT-TDGPTKEFTLSASTTETLLS 82

Query: 1327 NLLPGTEYVVSVSSVYEQHESTPLRGR 1353
             L+P TEYVV+++S  E  ES P+ G+
Sbjct: 83   ELVPETEYVVTITSYDEVEESVPVIGQ 109



 Score = 50.1 bits (118), Expect = 3e-05
 Identities = 35/125 (28%), Positives = 58/125 (46%), Gaps = 7/125 (5%)

Query: 1624 LVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGE 1683
            L+ +    +D P  L F  +D +++ ++W  P   +  YR+T     DG  + F      
Sbjct: 17   LLSSIEAEVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTTDGPTKEFTLSAST 76

Query: 1684 EDTAELQGLRPGSEYTVSVVALHDDMESQPLIG-----TQSTAIPAPTDLKFTQVTPTSL 1738
             +T  L  L P +EY V++ +  +  ES P+IG     T S+  P       T++   S+
Sbjct: 77   TETL-LSELVPETEYVVTITSYDEVEESVPVIGQLTIQTGSSTKPVEKKPGKTEIQKCSV 135

Query: 1739 SAQWT 1743
            SA WT
Sbjct: 136  SA-WT 139



 Score = 50.1 bits (118), Expect = 3e-05
 Identities = 31/86 (36%), Positives = 44/86 (51%), Gaps = 1/86 (1%)

Query: 1358 LDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTN 1417
            +D P+ ++F  I  N+  + W  P   I GYRI   P    G  +E  +  S     L+ 
Sbjct: 25   VDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTT-DGPTKEFTLSASTTETLLSE 83

Query: 1418 LTPGTEYVVSIVALNGREESPLLIGQ 1443
            L P TEYVV+I + +  EES  +IGQ
Sbjct: 84   LVPETEYVVTITSYDEVEESVPVIGQ 109



 Score = 48.9 bits (115), Expect = 6e-05
 Identities = 26/96 (27%), Positives = 47/96 (48%), Gaps = 1/96 (1%)

Query: 1714 LIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPD 1773
            L+ +    +  P+DL F  +   ++   W  P   + GYR+ V P    GP KE  L+  
Sbjct: 17   LLSSIEAEVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDP-TTDGPTKEFTLSAS 75

Query: 1774 SSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVT 1809
            ++  ++S L+  T+Y V++ +  +   S P  G +T
Sbjct: 76   TTETLLSELVPETEYVVTITSYDEVEESVPVIGQLT 111



 Score = 47.8 bits (112), Expect = 1e-04
 Identities = 29/117 (24%), Positives = 56/117 (47%), Gaps = 5/117 (4%)

Query: 1700 VSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPK 1759
            +S V    D +   L+  +    P P++L   +V+   +   W P    +TGY+V +TP 
Sbjct: 313  ISQVCSGVDEQLGELVSGEEVVEP-PSNLIAMEVSSKYVKLNWNPSPSPVTGYKVILTPM 371

Query: 1760 EKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSP 1816
                    +++ P ++++ V  L   T+Y++SV A+K   +S P    ++ +E   P
Sbjct: 372  TAGSRQHALSVGPQTTTLSVRDLSADTEYQISVSAMKGMTSSEP----ISIMEKTQP 424



 Score = 45.1 bits (105), Expect = 8e-04
 Identities = 28/96 (29%), Positives = 49/96 (51%), Gaps = 4/96 (4%)

Query: 1164 APIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEE 1223
            A +++ +   + PP++L+ +   D   + +SW +   P I GYRIT  PT    G + E 
Sbjct: 15   ALLLSSIEAEVDPPSDLNFKII-DENTVHMSWAKPVDP-IVGYRITVDPTT--DGPTKEF 70

Query: 1224 VVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPI 1259
             + A  +      L P  EY V++ +  + +ESVP+
Sbjct: 71   TLSASTTETLLSELVPETEYVVTITSYDEVEESVPV 106



 Score = 45.1 bits (105), Expect = 8e-04
 Identities = 23/110 (20%), Positives = 53/110 (48%), Gaps = 1/110 (0%)

Query: 790 VYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSV 849
           + Q+    ++ L    S     + P +    +V    + + W+   +P+TGY+++ +P  
Sbjct: 313 ISQVCSGVDEQLGELVSGEEVVEPPSNLIAMEVSSKYVKLNWNPSPSPVTGYKVILTPMT 372

Query: 850 EGSSTE-LNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQET 898
            GS    L++     ++++ DL    +Y I++ A++    S P+ I ++T
Sbjct: 373 AGSRQHALSVGPQTTTLSVRDLSADTEYQISVSAMKGMTSSEPISIMEKT 422



 Score = 44.7 bits (104), Expect = 0.001
 Identities = 25/96 (26%), Positives = 44/96 (45%)

Query: 1896 VIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGV 1955
            ++     ++ PSNL  +  +   + ++W P  + +TGY +      +  R+      P  
Sbjct: 327  LVSGEEVVEPPSNLIAMEVSSKYVKLNWNPSPSPVTGYKVILTPMTAGSRQHALSVGPQT 386

Query: 1956 TEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKT 1991
            T  ++  L   TEY I V A+K    SEP+   +KT
Sbjct: 387  TTLSVRDLSADTEYQISVSAMKGMTSSEPISIMEKT 422



 Score = 44.3 bits (103), Expect = 0.001
 Identities = 36/131 (27%), Positives = 52/131 (39%), Gaps = 21/131 (16%)

Query: 1439 LLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPG 1498
            LL+       D P DL        ++ +SW  P   +  YRIT   T  + P +EFT+  
Sbjct: 16   LLLSSIEAEVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTT-DGPTKEFTLSA 74

Query: 1499 SKSTATISGLKPGVDYTITVYAV----------------TGRGDSPASSKPISINYRTEI 1542
            S +   +S L P  +Y +T+ +                 TG    P   KP     +TEI
Sbjct: 75   STTETLLSELVPETEYVVTITSYDEVEESVPVIGQLTIQTGSSTKPVEKKP----GKTEI 130

Query: 1543 DKPSQMQVTDV 1553
             K S    TD+
Sbjct: 131  QKCSVSAWTDL 141



 Score = 43.1 bits (100), Expect = 0.003
 Identities = 29/102 (28%), Positives = 46/102 (45%), Gaps = 9/102 (8%)

Query: 1903 IDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITG 1962
            +D PS+L F     N++ +SW  P   I GY I  +     P +         TE  ++ 
Sbjct: 25   VDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTTDGPTKEFTL-SASTTETLLSE 83

Query: 1963 LEPGTEYTIYVIALKNNQKSEPLIGR--------KKTVQKTP 1996
            L P TEY + + +    ++S P+IG+         K V+K P
Sbjct: 84   LVPETEYVVTITSYDEVEESVPVIGQLTIQTGSSTKPVEKKP 125



 Score = 36.2 bits (82), Expect = 0.39
 Identities = 22/103 (21%), Positives = 45/103 (43%), Gaps = 1/103 (0%)

Query: 1795 LKDTLTSRPAQGVVTTLE-NVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANG 1853
            L   L +  A  +++++E  V PP         E T+ +SW    + I G+++   P   
Sbjct: 5    LPPALAALGAALLLSSIEAEVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTTD 64

Query: 1854 QTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVV 1896
                + T+        ++ L P T+Y + + + ++   S PV+
Sbjct: 65   GPTKEFTLSASTTETLLSELVPETEYVVTITSYDEVEESVPVI 107



 Score = 36.2 bits (82), Expect = 0.39
 Identities = 33/168 (19%), Positives = 67/168 (39%), Gaps = 14/168 (8%)

Query: 1807 VVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPAN-GQTPIQRTIKPDV 1865
            +V+  E V PP      + +   + ++W      +TG++V   P   G      ++ P  
Sbjct: 327  LVSGEEVVEPPSNLIAMEVSSKYVKLNWNPSPSPVTGYKVILTPMTAGSRQHALSVGPQT 386

Query: 1866 RSYTITGLQPGTDYKIYLYTLNDNARSSP-----------VVIDASTAIDAPSNLRFLAT 1914
             + ++  L   T+Y+I +  +     S P           V ++ S  +D  +++ FL  
Sbjct: 387  TTLSVRDLSADTEYQISVSAMKGMTSSEPISIMEKTQPMKVQVECSRGVDIKADIVFLVD 446

Query: 1915 TPNSL-LVSWQPPRARITGYIIKYE-KPGSPPREVVPRPRPGVTEATI 1960
               S+ + ++   RA +   +  +E  P      +V   R   TE T+
Sbjct: 447  GSYSIGIANFVKVRAFLEVLVKSFEISPNRVQISLVQYSRDPHTEFTL 494



 Score = 35.0 bits (79), Expect = 0.86
 Identities = 24/95 (25%), Positives = 38/95 (40%), Gaps = 1/95 (1%)

Query: 907  VPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTG 966
            V  P DL F  + +  V + W  P   + GYR+ V P    G   +    +  T   ++ 
Sbjct: 25   VDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTT-DGPTKEFTLSASTTETLLSE 83

Query: 967  LSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPT 1001
            L P   Y   + +     ES P+  Q T +  + T
Sbjct: 84   LVPETEYVVTITSYDEVEESVPVIGQLTIQTGSST 118



 Score = 33.5 bits (75), Expect = 2.5
 Identities = 18/79 (22%), Positives = 37/79 (46%), Gaps = 6/79 (7%)

Query: 738 VSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDG 797
           +SW    D + G+R+  + + +G   ++  L ++ T   + +L+P  +Y+V +    E  
Sbjct: 43  MSWAKPVDPIVGYRITVDPTTDGPTKEF-TLSASTTETLLSELVPETEYVVTITSYDEVE 101

Query: 798 EQ-----SLILSTSQTTAP 811
           E       L + T  +T P
Sbjct: 102 ESVPVIGQLTIQTGSSTKP 120



 Score = 32.7 bits (73), Expect = 4.3
 Identities = 29/126 (23%), Positives = 56/126 (44%), Gaps = 8/126 (6%)

Query: 1425 VVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGE 1484
            ++S V     E+   L+  +  V + P +L  +  +   + ++W+     V  Y++    
Sbjct: 312  IISQVCSGVDEQLGELVSGEEVV-EPPSNLIAMEVSSKYVKLNWNPSPSPVTGYKVILTP 370

Query: 1485 TGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDK 1544
                S     +V    +T ++  L    +Y I+V A+ G      SS+PISI  +T+   
Sbjct: 371  MTAGSRQHALSVGPQTTTLSVRDLSADTEYQISVSAMKGM----TSSEPISIMEKTQ--- 423

Query: 1545 PSQMQV 1550
            P ++QV
Sbjct: 424  PMKVQV 429


>gi|153946395 tenascin C precursor [Homo sapiens]
          Length = 2201

 Score =  360 bits (925), Expect = 7e-99
 Identities = 325/1394 (23%), Positives = 584/1394 (41%), Gaps = 73/1394 (5%)

Query: 609  SGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTI 668
            S P ++ +TE   +  +  + W+      +++Y++ + P +  G   +  +PG   S  I
Sbjct: 624  SPPKDLVVTEVTEETVN--LAWD--NEMRVTEYLVVYTPTHEGGLEMQFRVPGDQTSTII 679

Query: 669  KGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESV 728
            + L+PGV Y  ++ +I +                S PV++   T    P           
Sbjct: 680  QELEPGVEYFIRVFAILE-------------NKKSIPVSARVATYLPAP------EGLKF 720

Query: 729  TEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYL-DLPSTATSVNIPDLLPGRKYI 787
              I  +S  V W         + + +    + DE +    L    TS     L PG++Y 
Sbjct: 721  KSIKETSVEVEWDPLDIAFETWEIIFRNMNKEDEGEITKSLRRPETSYRQTGLAPGQEYE 780

Query: 788  VNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYS- 846
            ++++ I ++  +   L    TT  DAP    V  V DT+ ++ W +P A I G  + Y  
Sbjct: 781  ISLH-IVKNNTRGPGLKRVTTTRLDAPSQIEVKDVTDTTALITWFKPLAEIDGIELTYGI 839

Query: 847  PSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDT 906
              V G  T ++L E  N  ++ +L+P  +Y +++ +   +  S P   +  TTG      
Sbjct: 840  KDVPGDRTTIDLTEDENQYSIGNLKPDTEYEVSLISRRGDMSSNPAK-ETFTTG------ 892

Query: 907  VPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQ-RLPISRN--TFAE 963
            + +PR+L+ V  TD  +T+ W   ++A+  YR+   P++  G+H +  +P S+   T   
Sbjct: 893  LDAPRNLRRVSQTDNSITLEWRNGKAAIDSYRIKYAPIS-GGDHAEVDVPKSQQATTKTT 951

Query: 964  VTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQ 1023
            +TGL PG  Y   V AV   +ES P T    T+LD P +LQ     ++++ + W  P A+
Sbjct: 952  LTGLRPGTEYGIGVSAVKEDKESNPATINAATELDTPKDLQVSETAETSLTLLWKTPLAK 1011

Query: 1024 ITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFT 1083
               YRL   L   GQ     +  + + Y LR L+P  EY V L A KG  +S  A    +
Sbjct: 1012 FDRYRLNYSLPT-GQWVGVQLPRNTTSYVLRGLEPGQEYNVLLTAEKGRHKSKPARVKAS 1070

Query: 1084 TLQPGSSIPPYNTEVTETTIVITWTPAPRI--GFKLGVRPSQGGEAPREVTSDSG--SIV 1139
            T Q         TEV    + + WT A +    F + V+ +   EA R +T      ++ 
Sbjct: 1071 TEQAPELENLTVTEVGWDGLRLNWTAADQAYEHFIIQVQEANKVEAARNLTVPGSLRAVD 1130

Query: 1140 VSGLTPGVEYVYTIQVLRDGQERDAPIVN-KVVTPLSPPTNLHLEANPDTGVLTVSWERS 1198
            + GL     Y  +I  +  G     P+++ +  T  +P     + A      L ++W   
Sbjct: 1131 IPGLKAATPYTVSIYGVIQGYR--TPVLSAEASTGETPNLGEVVVAEVGWDALKLNW--- 1185

Query: 1199 TTPDITGYRITTTPTNGQQGNSLEEV----VHADQSSCTFDNLSPGLEYNVSVYTVKDDK 1254
            T P+   Y         Q+ +++E      V     S     L     Y +++  V  D 
Sbjct: 1186 TAPE-GAYEYFFIQV--QEADTVEAAQNLTVPGGLRSTDLPGLKAATHYTITIRGVTQDF 1242

Query: 1255 ESVPIS-DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAE 1313
             + P+S + +   VP   +L  T +  D +R+ W  P       F ++       E+   
Sbjct: 1243 STTPLSVEVLTEEVPDMGNLTVTEVSWDALRLNWTTPDGT-YDQFTIQVQEADQVEEAHN 1301

Query: 1314 LSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKT-GLDSPTGIDFSDITAN 1372
            L++  S  ++ +  L  GT Y V++      H + PL     T  L     +  S++  +
Sbjct: 1302 LTVPGSLRSMEIPGLRAGTPYTVTLHGEVRGHSTRPLAVEVVTEDLPQLGDLAVSEVGWD 1361

Query: 1373 SFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN 1432
               ++W A       + I+    +     +   +P S  ++ +  L   T Y VSI  + 
Sbjct: 1362 GLRLNWTAADNAYEHFVIQVQEVNKVEAAQNLTLPGSLRAVDIPGLEAATPYRVSIYGVI 1421

Query: 1433 GREESPLLIGQQSTVSDVP-RDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPV 1491
                +P+L  + ST  +    +L V   TP S  +SW A       + I   ++      
Sbjct: 1422 RGYRTPVLSAEASTAKEPEIGNLNVSDITPESFNLSWMATDGIFETFTIEIIDSNRLLET 1481

Query: 1492 QEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPA-SSKPISINYRTE-IDKPSQMQ 1549
             E+ + G++ TA ISGL P  D+ + +      G +P+  +K IS    TE +     + 
Sbjct: 1482 VEYNISGAERTAHISGLPPSTDFIVYL-----SGLAPSIRTKTISATATTEALPLLENLT 1536

Query: 1550 VTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYV 1609
            ++D+     +V W+ S +    + VT          +  T    Q ++ + GL   + Y 
Sbjct: 1537 ISDINPYGFTVSWMASENAFDSFLVTVVDSGKLLDPQEFTLSGTQRKLELRGLITGIGYE 1596

Query: 1610 VSVYAQNPSGESQPLVQTAVTNID-RPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSS 1668
            V V       +++PL    VT  +     L  +D   D  +++W + +G    + +    
Sbjct: 1597 VMVSGFTQGHQTKPLRAEIVTEAEPEVDNLLVSDATPDGFRLSWTADEGVFDNFVLKIRD 1656

Query: 1669 PEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDL 1728
             +     L       E T ++ GLR  +EY + +  +     SQ +    +TA+ +P ++
Sbjct: 1657 TKKQSEPLEITLLAPERTRDITGLREATEYEIELYGISKGRRSQTVSAIATTAMGSPKEV 1716

Query: 1729 KFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKY 1788
             F+ +T  S +  W  P  Q+  +R+   P     P   + +    +   +  L+   +Y
Sbjct: 1717 IFSDITENSATVSWRAPTAQVESFRITYVPITGGTPSM-VTVDGTKTQTRLVKLIPGVEY 1775

Query: 1789 EVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDA 1848
             VS+ A+K    S P  G  TT   +  P      + T++     W+    T+  + + +
Sbjct: 1776 LVSIIAMKGFEESEPVSGSFTTA--LDGPSGLVTANITDSEALARWQPAIATVDSYVI-S 1832

Query: 1849 VPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSN 1908
                    I RT+  +   Y +T L+P T+Y + ++      +SS +    +T +D+P +
Sbjct: 1833 YTGEKVPEITRTVSGNTVEYALTDLEPATEYTLRIFAEKGPQKSSTITAKFTTDLDSPRD 1892

Query: 1909 LRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTE 1968
            L        + L++W+PPRA +TGY++ YE      +EV+    P  T  ++  L P T 
Sbjct: 1893 LTATEVQSETALLTWRPPRASVTGYLLVYESVDGTVKEVI--VGPDTTSYSLADLSPSTH 1950

Query: 1969 YTIYVIALKNNQKS 1982
            YT  + AL    +S
Sbjct: 1951 YTAKIQALNGPLRS 1964



 Score =  340 bits (872), Expect = 1e-92
 Identities = 309/1304 (23%), Positives = 528/1304 (40%), Gaps = 79/1304 (6%)

Query: 728  VTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYI 787
            VTE+T  +  ++W +    V+ + V Y  + EG       +P   TS  I +L PG +Y 
Sbjct: 631  VTEVTEETVNLAWDNEM-RVTEYLVVYTPTHEGGLEMQFRVPGDQTSTIIQELEPGVEYF 689

Query: 788  VNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVY-- 845
            + V+ I E+ ++S+ +S    T   AP       + +TS+ V W         + I++  
Sbjct: 690  IRVFAILEN-KKSIPVSARVATYLPAPEGLKFKSIKETSVEVEWDPLDIAFETWEIIFRN 748

Query: 846  -SPSVEGSSTE-LNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPR 903
             +   EG  T+ L  PET+   T   L PG +Y I+++ V+ N     +    +   T R
Sbjct: 749  MNKEDEGEITKSLRRPETSYRQT--GLAPGQEYEISLHIVKNNTRGPGL----KRVTTTR 802

Query: 904  SDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQ-RLPISRNTFA 962
             D   +P  ++  +VTD    I W  P + + G  +     ++PG+     L    N ++
Sbjct: 803  LD---APSQIEVKDVTDTTALITWFKPLAEIDGIELTYGIKDVPGDRTTIDLTEDENQYS 859

Query: 963  EVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRA 1022
             +  L P   Y   + +      S P     TT LDAP NL+ V++TD+++ + W   +A
Sbjct: 860  -IGNLKPDTEYEVSLISRRGDMSSNPAKETFTTGLDAPRNLRRVSQTDNSITLEWRNGKA 918

Query: 1023 QITGYRLTVGLTRRGQPRQYNVGPS---VSKYPLRNLQPASEYTVSLVAIKGNQESPKAT 1079
             I  YR+       G   + +V  S    +K  L  L+P +EY + + A+K ++ES  AT
Sbjct: 919  AIDSYRIKYAPISGGDHAEVDVPKSQQATTKTTLTGLRPGTEYGIGVSAVKEDKESNPAT 978

Query: 1080 -GVFTTLQPGSSIPPYNTEVTETTIVITW-TPAP-----RIGFKLGVRPSQGGEAPREVT 1132
                T L     +    +E  ET++ + W TP       R+ + L      G + PR  T
Sbjct: 979  INAATELDTPKDLQV--SETAETSLTLLWKTPLAKFDRYRLNYSLPTGQWVGVQLPRNTT 1036

Query: 1133 SDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLT 1192
            S     V+ GL PG EY   +     G+ +  P   K  T  +P          +  V  
Sbjct: 1037 S----YVLRGLEPGQEY-NVLLTAEKGRHKSKPARVKASTEQAPELE-------NLTVTE 1084

Query: 1193 VSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPG------------ 1240
            V W+        G R+  T  +    + + +V  A++     +   PG            
Sbjct: 1085 VGWD--------GLRLNWTAADQAYEHFIIQVQEANKVEAARNLTVPGSLRAVDIPGLKA 1136

Query: 1241 -LEYNVSVY-TVKDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNF 1298
               Y VS+Y  ++  +  V  ++      P   ++    +G D +++ W  P       F
Sbjct: 1137 ATPYTVSIYGVIQGYRTPVLSAEASTGETPNLGEVVVAEVGWDALKLNWTAPEGA-YEYF 1195

Query: 1299 LVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGL 1358
             ++       E    L++     +  L  L   T Y +++  V +   +TPL     T  
Sbjct: 1196 FIQVQEADTVEAAQNLTVPGGLRSTDLPGLKAATHYTITIRGVTQDFSTTPLSVEVLTEE 1255

Query: 1359 DSPTG-IDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTN 1417
                G +  ++++ ++  ++W  P  T   + I+              VP S  S+ +  
Sbjct: 1256 VPDMGNLTVTEVSWDALRLNWTTPDGTYDQFTIQVQEADQVEEAHNLTVPGSLRSMEIPG 1315

Query: 1418 LTPGTEYVVSIVA-LNGREESPLLIGQQSTVSDVPR--DLEVVAATPTSLLISWDAPAVT 1474
            L  GT Y V++   + G    PL +  +    D+P+  DL V       L ++W A    
Sbjct: 1316 LRAGTPYTVTLHGEVRGHSTRPLAV--EVVTEDLPQLGDLAVSEVGWDGLRLNWTAADNA 1373

Query: 1475 VRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPI 1534
              ++ I   E       Q  T+PGS     I GL+    Y +++Y V     +P  S   
Sbjct: 1374 YEHFVIQVQEVNKVEAAQNLTLPGSLRAVDIPGLEAATPYRVSIYGVIRGYRTPVLSAEA 1433

Query: 1535 SINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQ 1594
            S     EI     + V+D+   S ++ W+ +      + +     N    T        +
Sbjct: 1434 STAKEPEI---GNLNVSDITPESFNLSWMATDGIFETFTIEIIDSNRLLETVEYNISGAE 1490

Query: 1595 TEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTN-IDRPKGLAFTDVDVDSIKIAWE 1653
                I GL P+ +++V +    PS  ++ +  TA T  +   + L  +D++     ++W 
Sbjct: 1491 RTAHISGLPPSTDFIVYLSGLAPSIRTKTISATATTEALPLLENLTISDINPYGFTVSWM 1550

Query: 1654 SPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQP 1713
            + +     + VT       +        G +   EL+GL  G  Y V V       +++P
Sbjct: 1551 ASENAFDSFLVTVVDSGKLLDPQEFTLSGTQRKLELRGLITGIGYEVMVSGFTQGHQTKP 1610

Query: 1714 LIGTQST-AIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAP 1772
            L     T A P   +L  +  TP      WT        + +++   +K     EI L  
Sbjct: 1611 LRAEIVTEAEPEVDNLLVSDATPDGFRLSWTADEGVFDNFVLKIRDTKKQSEPLEITLLA 1670

Query: 1773 DSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITI 1832
               +  ++GL  AT+YE+ +Y +     S+    + TT   +  P+    +D TE + T+
Sbjct: 1671 PERTRDITGLREATEYEIELYGISKGRRSQTVSAIATTA--MGSPKEVIFSDITENSATV 1728

Query: 1833 SWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARS 1892
            SWR  T  +  F++  VP  G TP   T+        +  L PG +Y + +  +     S
Sbjct: 1729 SWRAPTAQVESFRITYVPITGGTPSMVTVDGTKTQTRLVKLIPGVEYLVSIIAMKGFEES 1788

Query: 1893 SPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPR 1952
             PV    +TA+D PS L     T +  L  WQP  A +  Y+I Y   G    E+     
Sbjct: 1789 EPVSGSFTTALDGPSGLVTANITDSEALARWQPAIATVDSYVISY--TGEKVPEITRTVS 1846

Query: 1953 PGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQKTP 1996
                E  +T LEP TEYT+ + A K  QKS  +  +  T   +P
Sbjct: 1847 GNTVEYALTDLEPATEYTLRIFAEKGPQKSSTITAKFTTDLDSP 1890



 Score =  313 bits (803), Expect = 1e-84
 Identities = 308/1264 (24%), Positives = 532/1264 (42%), Gaps = 96/1264 (7%)

Query: 665  SYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVAT 724
            SY   GL PG  YE  L  ++               +T  P      T      S +   
Sbjct: 767  SYRQTGLAPGQEYEISLHIVKN--------------NTRGPGLKRVTTTRLDAPSQI--- 809

Query: 725  SESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGR 784
               V ++T ++ +++W      + G  + Y + +   +   +DL       +I +L P  
Sbjct: 810  --EVKDVTDTTALITWFKPLAEIDGIELTYGIKDVPGDRTTIDLTEDENQYSIGNLKPDT 867

Query: 785  KYIVNVYQISEDGEQSLILSTSQ-TTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRI 843
            +Y V++  IS  G+ S   +    TT  DAP +       D SI + W   +A I  YRI
Sbjct: 868  EYEVSL--ISRRGDMSSNPAKETFTTGLDAPRNLRRVSQTDNSITLEWRNGKAAIDSYRI 925

Query: 844  VYSPSVEGSSTELNLPETANSVT---LSDLQPGVQYNITIYAVEENQESTPVVIQQETTG 900
             Y+P   G   E+++P++  + T   L+ L+PG +Y I + AV+E++ES P  I   T  
Sbjct: 926  KYAPISGGDHAEVDVPKSQQATTKTTLTGLRPGTEYGIGVSAVKEDKESNPATINAATE- 984

Query: 901  TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT 960
                  + +P+DLQ  E  +  +T++W  P +    YR++    +LP      + + RNT
Sbjct: 985  ------LDTPKDLQVSETAETSLTLLWKTPLAKFDRYRLNY---SLPTGQWVGVQLPRNT 1035

Query: 961  FAEVT-GLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPT--NLQFVNETDSTVLVRW 1017
             + V  GL PG  Y   + A     +SKP   + +T+  AP   NL         + + W
Sbjct: 1036 TSYVLRGLEPGQEYNVLLTAEKGRHKSKPARVKASTE-QAPELENLTVTEVGWDGLRLNW 1094

Query: 1018 TPPRAQITGYRLTVGLTRRGQP-RQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESP 1076
            T        + + V    + +  R   V  S+    +  L+ A+ YTVS+  +     +P
Sbjct: 1095 TAADQAYEHFIIQVQEANKVEAARNLTVPGSLRAVDIPGLKAATPYTVSIYGVIQGYRTP 1154

Query: 1077 KATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFK---LGVRPSQGGEAPREVTS 1133
              +   +T +  +       EV    + + WT AP   ++   + V+ +   EA + +T 
Sbjct: 1155 VLSAEASTGETPNLGEVVVAEVGWDALKLNWT-APEGAYEYFFIQVQEADTVEAAQNLTV 1213

Query: 1134 DSG--SIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVL 1191
              G  S  + GL     Y  TI+    G  +D        TPLS    +  E  PD G L
Sbjct: 1214 PGGLRSTDLPGLKAATHYTITIR----GVTQDFS-----TTPLS--VEVLTEEVPDMGNL 1262

Query: 1192 TV---SWERS----TTPDITGYRITTTPTNGQQGNSLEEV----VHADQSSCTFDNLSPG 1240
            TV   SW+      TTPD T  + T      Q+ + +EE     V     S     L  G
Sbjct: 1263 TVTEVSWDALRLNWTTPDGTYDQFTIQV---QEADQVEEAHNLTVPGSLRSMEIPGLRAG 1319

Query: 1241 LEYNVSVYTVKDDKESVPIS-DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFL 1299
              Y V+++       + P++ + +   +P   DL  + +G D +R+ W    +    +F+
Sbjct: 1320 TPYTVTLHGEVRGHSTRPLAVEVVTEDLPQLGDLAVSEVGWDGLRLNWTAADNA-YEHFV 1378

Query: 1300 VRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLD 1359
            ++   V   E    L++  S  AV +  L   T Y VS+  V   + +  L     T  +
Sbjct: 1379 IQVQEVNKVEAAQNLTLPGSLRAVDIPGLEAATPYRVSIYGVIRGYRTPVLSAEASTAKE 1438

Query: 1360 SPTG-IDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNL 1418
               G ++ SDIT  SF + W+A       + I     +      E  +  +  +  ++ L
Sbjct: 1439 PEIGNLNVSDITPESFNLSWMATDGIFETFTIEIIDSNRLLETVEYNISGAERTAHISGL 1498

Query: 1419 TPGTEYVVSIVALNGREESPLLIGQQSTVSDVP--RDLEVVAATPTSLLISWDAPAVTVR 1476
             P T+++V +  L     +   I   +T   +P   +L +    P    +SW A      
Sbjct: 1499 PPSTDFIVYLSGLAPSIRTKT-ISATATTEALPLLENLTISDINPYGFTVSWMASENAFD 1557

Query: 1477 YYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISI 1536
             + +T  ++G     QEFT+ G++    + GL  G+ Y + V   T        +KP+  
Sbjct: 1558 SFLVTVVDSGKLLDPQEFTLSGTQRKLELRGLITGIGYEVMVSGFT----QGHQTKPLRA 1613

Query: 1537 NYRTEID-KPSQMQVTDVQDNSISVKWLPSSSPVTGY--RVTTTPKNGPGPTKTKTAGPD 1593
               TE + +   + V+D   +   + W         +  ++  T K    P +     P+
Sbjct: 1614 EIVTEAEPEVDNLLVSDATPDGFRLSWTADEGVFDNFVLKIRDTKKQSE-PLEITLLAPE 1672

Query: 1594 QTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWE 1653
            +T   I GL+   EY + +Y  +    SQ +   A T +  PK + F+D+  +S  ++W 
Sbjct: 1673 RTR-DITGLREATEYEIELYGISKGRRSQTVSAIATTAMGSPKEVIFSDITENSATVSWR 1731

Query: 1654 SPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQP 1713
            +P  QV  +R+TY     G   +    DG +    L  L PG EY VS++A+    ES+P
Sbjct: 1732 APTAQVESFRITYVPITGGTPSMVTV-DGTKTQTRLVKLIPGVEYLVSIIAMKGFEESEP 1790

Query: 1714 LIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPD 1773
            + G+ +TA+  P+ L    +T +   A+W P    +  Y +  T ++    + EI     
Sbjct: 1791 VSGSFTTALDGPSGLVTANITDSEALARWQPAIATVDSYVISYTGEK----VPEITRTVS 1846

Query: 1774 SSSV--VVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTIT 1831
             ++V   ++ L  AT+Y + ++A K    S       TT  ++  PR    T+    T  
Sbjct: 1847 GNTVEYALTDLEPATEYTLRIFAEKGPQKSSTITAKFTT--DLDSPRDLTATEVQSETAL 1904

Query: 1832 ISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNAR 1891
            ++WR    ++TG+ +     +G T  +  + PD  SY++  L P T Y   +  LN   R
Sbjct: 1905 LTWRPPRASVTGYLLVYESVDG-TVKEVIVGPDTTSYSLADLSPSTHYTAKIQALNGPLR 1963

Query: 1892 SSPV 1895
            S+ +
Sbjct: 1964 SNMI 1967



 Score =  278 bits (712), Expect = 3e-74
 Identities = 272/1120 (24%), Positives = 450/1120 (40%), Gaps = 59/1120 (5%)

Query: 907  VPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTG 966
            V  P+DL   EVT+  V + W   E  VT Y V   P +  G   Q       T   +  
Sbjct: 623  VSPPKDLVVTEVTEETVNLAW-DNEMRVTEYLVVYTPTHEGGLEMQFRVPGDQTSTIIQE 681

Query: 967  LSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITG 1026
            L PGV Y+ +VFA+   ++S P++A+  T L AP  L+F +  +++V V W P       
Sbjct: 682  LEPGVEYFIRVFAILENKKSIPVSARVATYLPAPEGLKFKSIKETSVEVEWDPLDIAFET 741

Query: 1027 YRL---TVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFT 1083
            + +    +     G+  +    P  S Y    L P  EY +SL  +K N   P    V T
Sbjct: 742  WEIIFRNMNKEDEGEITKSLRRPETS-YRQTGLAPGQEYEISLHIVKNNTRGPGLKRVTT 800

Query: 1084 T-LQPGSSIPPYNTEVTETTIVITW-TPAPRI-GFKL--GVRPSQGGEAPREVTSDSGSI 1138
            T L   S I     +VT+TT +ITW  P   I G +L  G++   G     ++T D    
Sbjct: 801  TRLDAPSQIEV--KDVTDTTALITWFKPLAEIDGIELTYGIKDVPGDRTTIDLTEDENQY 858

Query: 1139 VVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERS 1198
             +  L P  EY  ++ + R G     P      T L  P NL   +  D  + T+ W R+
Sbjct: 859  SIGNLKPDTEYEVSL-ISRRGDMSSNPAKETFTTGLDAPRNLRRVSQTDNSI-TLEW-RN 915

Query: 1199 TTPDITGYRITTTPTNGQQGNSLEEVVHADQ---SSCTFDNLSPGLEYNVSVYTVKDDKE 1255
                I  YRI   P +G  G+  E  V   Q   +  T   L PG EY + V  VK+DKE
Sbjct: 916  GKAAIDSYRIKYAPISG--GDHAEVDVPKSQQATTKTTLTGLRPGTEYGIGVSAVKEDKE 973

Query: 1256 SVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELS 1315
            S P +      +  P DL+ +     ++ + W  P +     + + YS    +     + 
Sbjct: 974  SNPATINAATELDTPKDLQVSETAETSLTLLWKTPLA-KFDRYRLNYSLPTGQ--WVGVQ 1030

Query: 1316 ISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKT-GLDSPTGIDFSDITANSF 1374
            +  +  + VL  L PG EY V +++   +H+S P R +  T        +  +++  +  
Sbjct: 1031 LPRNTTSYVLRGLEPGQEYNVLLTAEKGRHKSKPARVKASTEQAPELENLTVTEVGWDGL 1090

Query: 1375 TVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGR 1434
             ++W A       + I+    +     R   VP S  ++ +  L   T Y VSI  +   
Sbjct: 1091 RLNWTAADQAYEHFIIQVQEANKVEAARNLTVPGSLRAVDIPGLKAATPYTVSIYGVIQG 1150

Query: 1435 EESPLLIGQQSTVSDVPRDLEVVAATP--TSLLISWDAPAVTVRYYRITYGETGGNSPVQ 1492
              +P+L  + ST  + P   EVV A     +L ++W AP     Y+ I   E       Q
Sbjct: 1151 YRTPVLSAEAST-GETPNLGEVVVAEVGWDALKLNWTAPEGAYEYFFIQVQEADTVEAAQ 1209

Query: 1493 EFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRT-EIDKPSQMQVT 1551
              TVPG   +  + GLK    YTIT+  VT       S+ P+S+   T E+     + VT
Sbjct: 1210 NLTVPGGLRSTDLPGLKAATHYTITIRGVT----QDFSTTPLSVEVLTEEVPDMGNLTVT 1265

Query: 1552 DVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVS 1611
            +V  +++ + W         + +     +        T       M I GL+    Y V+
Sbjct: 1266 EVSWDALRLNWTTPDGTYDQFTIQVQEADQVEEAHNLTVPGSLRSMEIPGLRAGTPYTVT 1325

Query: 1612 VYAQNPSGESQPLVQTAVTNIDRPK--GLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSP 1669
            ++ +     ++PL    VT  D P+   LA ++V  D +++ W +       + +     
Sbjct: 1326 LHGEVRGHSTRPLAVEVVTE-DLPQLGDLAVSEVGWDGLRLNWTAADNAYEHFVIQVQEV 1384

Query: 1670 EDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTA-IPAPTDL 1728
                        G     ++ GL   + Y VS+  +     +  L    STA  P   +L
Sbjct: 1385 NKVEAAQNLTLPGSLRAVDIPGLEAATPYRVSIYGVIRGYRTPVLSAEASTAKEPEIGNL 1444

Query: 1729 KFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKY 1788
              + +TP S +  W   +     + + +    +     E N++    +  +SGL  +T +
Sbjct: 1445 NVSDITPESFNLSWMATDGIFETFTIEIIDSNRLLETVEYNISGAERTAHISGLPPSTDF 1504

Query: 1789 EVSVYALKDTLTSRPAQGVVTT-----LENVSPPRRARVTDATETTITISWRTKTETITG 1843
             V +  L  ++ ++      TT     LEN++      ++D      T+SW         
Sbjct: 1505 IVYLSGLAPSIRTKTISATATTEALPLLENLT------ISDINPYGFTVSWMASENAFDS 1558

Query: 1844 FQVDAVPANG-QTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSP----VVID 1898
            F V  V +     P + T+    R   + GL  G  Y++ +       ++ P    +V +
Sbjct: 1559 FLVTVVDSGKLLDPQEFTLSGTQRKLELRGLITGIGYEVMVSGFTQGHQTKPLRAEIVTE 1618

Query: 1899 ASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYE--KPGSPPREVVPRPRPGVT 1956
            A   +D   NL     TP+   +SW         +++K    K  S P E+         
Sbjct: 1619 AEPEVD---NLLVSDATPDGFRLSWTADEGVFDNFVLKIRDTKKQSEPLEITLLAPERTR 1675

Query: 1957 EATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQKTP 1996
            +  ITGL   TEY I +  +   ++S+ +     T   +P
Sbjct: 1676 D--ITGLREATEYEIELYGISKGRRSQTVSAIATTAMGSP 1713



 Score =  270 bits (689), Expect = 2e-71
 Identities = 277/1182 (23%), Positives = 475/1182 (40%), Gaps = 87/1182 (7%)

Query: 664  NSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVA 723
            N Y+I  LKP   YE  LIS          R D +    S P      TG   P + L  
Sbjct: 856  NQYSIGNLKPDTEYEVSLIS---------RRGDMS----SNPAKETFTTGLDAPRN-LRR 901

Query: 724  TSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPST---ATSVNIPDL 780
             S+     T +S  + W +    +  +R++Y     GD  + +D+P +    T   +  L
Sbjct: 902  VSQ-----TDNSITLEWRNGKAAIDSYRIKYAPISGGDHAE-VDVPKSQQATTKTTLTGL 955

Query: 781  LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITG 840
             PG +Y + V  + ED E +   + +  T  D P D  V +  +TS+ + W  P A    
Sbjct: 956  RPGTEYGIGVSAVKEDKESNPA-TINAATELDTPKDLQVSETAETSLTLLWKTPLAKFDR 1014

Query: 841  YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG 900
            YR+ YS    G    + LP    S  L  L+PG +YN+ + A +   +S P  ++  T  
Sbjct: 1015 YRLNYSLPT-GQWVGVQLPRNTTSYVLRGLEPGQEYNVLLTAEKGRHKSKPARVKAST-- 1071

Query: 901  TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT 960
                +  P   +L   EV    + + WT  + A   + + V   N   E  + L +  + 
Sbjct: 1072 ----EQAPELENLTVTEVGWDGLRLNWTAADQAYEHFIIQVQEANKV-EAARNLTVPGSL 1126

Query: 961  FA-EVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVL-VRWT 1018
             A ++ GL     Y   ++ V  G  +  L+A+ +T          V E     L + WT
Sbjct: 1127 RAVDIPGLKAATPYTVSIYGVIQGYRTPVLSAEASTGETPNLGEVVVAEVGWDALKLNWT 1186

Query: 1019 PPRAQITGYRLTVGLTRRGQPRQYNVGPS-VSKYPLRNLQPASEYTVSLVAIKGN-QESP 1076
             P      + + V      +  Q    P  +    L  L+ A+ YT+++  +  +   +P
Sbjct: 1187 APEGAYEYFFIQVQEADTVEAAQNLTVPGGLRSTDLPGLKAATHYTITIRGVTQDFSTTP 1246

Query: 1077 KATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRI--GFKLGVRPSQGGEAPREVTSD 1134
             +  V T   P        TEV+   + + WT        F + V+ +   E    +T  
Sbjct: 1247 LSVEVLTEEVPDMGNLTV-TEVSWDALRLNWTTPDGTYDQFTIQVQEADQVEEAHNLTVP 1305

Query: 1135 SG--SIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLT 1192
                S+ + GL  G  Y  T+     G     P+  +VVT   P          D  V  
Sbjct: 1306 GSLRSMEIPGLRAGTPYTVTLHGEVRGHST-RPLAVEVVTEDLPQLG-------DLAVSE 1357

Query: 1193 VSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLS----------PGLE 1242
            V W+        G R+  T  +    + + +V   ++      NL+          PGLE
Sbjct: 1358 VGWD--------GLRLNWTAADNAYEHFVIQVQEVNKVEAA-QNLTLPGSLRAVDIPGLE 1408

Query: 1243 ----YNVSVY-TVKDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTN 1297
                Y VS+Y  ++  +  V  ++      P   +L  ++I P++  ++W     I  T 
Sbjct: 1409 AATPYRVSIYGVIRGYRTPVLSAEASTAKEPEIGNLNVSDITPESFNLSWMATDGIFET- 1467

Query: 1298 FLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKT- 1356
            F +         +  E +IS ++    ++ L P T+++V +S +     +  +     T 
Sbjct: 1468 FTIEIIDSNRLLETVEYNISGAERTAHISGLPPSTDFIVYLSGLAPSIRTKTISATATTE 1527

Query: 1357 GLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLT 1416
             L     +  SDI    FTV W+A       + +          P+E  +  ++  + L 
Sbjct: 1528 ALPLLENLTISDINPYGFTVSWMASENAFDSFLVTVVDSGKLLDPQEFTLSGTQRKLELR 1587

Query: 1417 NLTPGTEYVVSIVALN-GREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTV 1475
             L  G  Y V +     G +  PL     +       +L V  ATP    +SW A     
Sbjct: 1588 GLITGIGYEVMVSGFTQGHQTKPLRAEIVTEAEPEVDNLLVSDATPDGFRLSWTADEGVF 1647

Query: 1476 RYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVT-GRGDSPASSKPI 1534
              + +   +T   S   E T+   + T  I+GL+   +Y I +Y ++ GR      S+ +
Sbjct: 1648 DNFVLKIRDTKKQSEPLEITLLAPERTRDITGLREATEYEIELYGISKGR-----RSQTV 1702

Query: 1535 SINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQ 1594
            S    T +  P ++  +D+ +NS +V W   ++ V  +R+T  P  G  P+     G  +
Sbjct: 1703 SAIATTAMGSPKEVIFSDITENSATVSWRAPTAQVESFRITYVPITGGTPSMVTVDGT-K 1761

Query: 1595 TEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWES 1654
            T+  +  L P VEY+VS+ A     ES+P+  +  T +D P GL   ++        W+ 
Sbjct: 1762 TQTRLVKLIPGVEYLVSIIAMKGFEESEPVSGSFTTALDGPSGLVTANITDSEALARWQP 1821

Query: 1655 PQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPL 1714
                V  Y ++Y+  +  + E+     G      L  L P +EYT+ + A     +S  +
Sbjct: 1822 AIATVDSYVISYTGEK--VPEITRTVSGNTVEYALTDLEPATEYTLRIFAEKGPQKSSTI 1879

Query: 1715 IGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDS 1774
                +T + +P DL  T+V   +    W PP   +TGY +    +   G +KE+ + PD+
Sbjct: 1880 TAKFTTDLDSPRDLTATEVQSETALLTWRPPRASVTGYLL--VYESVDGTVKEVIVGPDT 1937

Query: 1775 SSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSP 1816
            +S  ++ L  +T Y   + AL   L S   Q + TT+  + P
Sbjct: 1938 TSYSLADLSPSTHYTAKIQALNGPLRSNMIQTIFTTIGLLYP 1979



 Score =  208 bits (530), Expect = 4e-53
 Identities = 186/811 (22%), Positives = 334/811 (41%), Gaps = 56/811 (6%)

Query: 1352 GRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRN 1411
            G   + +  P  +  +++T  +  + W      +T Y + + P H  G   + RVP  + 
Sbjct: 617  GEDCSEVSPPKDLVVTEVTEETVNLAW-DNEMRVTEYLVVYTPTHEGGLEMQFRVPGDQT 675

Query: 1412 SITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAP 1471
            S  +  L PG EY + + A+   ++S  +  + +T    P  L+  +   TS+ + WD  
Sbjct: 676  STIIQELEPGVEYFIRVFAILENKKSIPVSARVATYLPAPEGLKFKSIKETSVEVEWDPL 735

Query: 1472 AVTVRYYRITYGETGGNSPVQ-EFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPAS 1530
             +    + I +         +   ++   +++   +GL PG +Y I+++ V      P  
Sbjct: 736  DIAFETWEIIFRNMNKEDEGEITKSLRRPETSYRQTGLAPGQEYEISLHIVKNNTRGPGL 795

Query: 1531 SKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTA 1590
             +  +    T +D PSQ++V DV D +  + W    + + G  +T   K+ PG   T   
Sbjct: 796  KRVTT----TRLDAPSQIEVKDVTDTTALITWFKPLAEIDGIELTYGIKDVPGDRTTIDL 851

Query: 1591 GPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKI 1650
              D+ + +I  L+P  EY VS+ ++     S P  +T  T +D P+ L       +SI +
Sbjct: 852  TEDENQYSIGNLKPDTEYEVSLISRRGDMSSNPAKETFTTGLDAPRNLRRVSQTDNSITL 911

Query: 1651 AWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAE--LQGLRPGSEYTVSVVALHDD 1708
             W + +  +  YR+ Y+    G H     P  ++ T +  L GLRPG+EY + V A+ +D
Sbjct: 912  EWRNGKAAIDSYRIKYAPISGGDHAEVDVPKSQQATTKTTLTGLRPGTEYGIGVSAVKED 971

Query: 1709 MESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEI 1768
             ES P     +T +  P DL+ ++   TSL+  W  P  +   YR+  +    TG    +
Sbjct: 972  KESNPATINAATELDTPKDLQVSETAETSLTLLWKTPLAKFDRYRLNYS--LPTGQWVGV 1029

Query: 1769 NLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATET 1828
             L  +++S V+ GL    +Y V + A K    S+PA+ V  + E         VT+    
Sbjct: 1030 QLPRNTTSYVLRGLEPGQEYNVLLTAEKGRHKSKPAR-VKASTEQAPELENLTVTEVGWD 1088

Query: 1829 TITISWRTKTETITGFQVDAVPANG-QTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLN 1887
             + ++W    +    F +    AN  +     T+   +R+  I GL+  T Y + +Y + 
Sbjct: 1089 GLRLNWTAADQAYEHFIIQVQEANKVEAARNLTVPGSLRAVDIPGLKAATPYTVSIYGVI 1148

Query: 1888 DNARSSPVVIDASTAIDAPSNLRFLATTP---NSLLVSWQPPRARITGYIIKYEKPGSPP 1944
               R+  +  +AST  + P NL  +       ++L ++W  P      + I+ ++  +  
Sbjct: 1149 QGYRTPVLSAEASTG-ETP-NLGEVVVAEVGWDALKLNWTAPEGAYEYFFIQVQEADTVE 1206

Query: 1945 REVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQKTPF----VTH 2000
                     G+    + GL+  T YTI +  +  +  + PL     T +        VT 
Sbjct: 1207 AAQNLTVPGGLRSTDLPGLKAATHYTITIRGVTQDFSTTPLSVEVLTEEVPDMGNLTVTE 1266

Query: 2001 PGYDT--GNGIQLPGTSGQQPSVGQQ--MIFEEH--------------GFRRTTPPTTAT 2042
              +D    N     GT  Q     Q+   + E H              G R  TP T   
Sbjct: 1267 VSWDALRLNWTTPDGTYDQFTIQVQEADQVEEAHNLTVPGSLRSMEIPGLRAGTPYTVTL 1326

Query: 2043 --PIR-HRPRPYP--------PNVGQEALSQT-----TISWAPFQDTSE-YIISCHPVGT 2085
               +R H  RP          P +G  A+S+       ++W    +  E ++I    V  
Sbjct: 1327 HGEVRGHSTRPLAVEVVTEDLPQLGDLAVSEVGWDGLRLNWTAADNAYEHFVIQVQEVNK 1386

Query: 2086 DEEPLQFRVPGTSTSATLTGLTRGATYNIIV 2116
             E      +PG+  +  + GL     Y + +
Sbjct: 1387 VEAAQNLTLPGSLRAVDIPGLEAATPYRVSI 1417



 Score =  207 bits (526), Expect = 1e-52
 Identities = 169/678 (24%), Positives = 290/678 (42%), Gaps = 71/678 (10%)

Query: 1540 TEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTI 1599
            +E+  P  + VT+V + ++++ W  +   VT Y V  TP +  G         DQT   I
Sbjct: 621  SEVSPPKDLVVTEVTEETVNLAW-DNEMRVTEYLVVYTPTHEGGLEMQFRVPGDQTSTII 679

Query: 1600 EGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQV 1659
            + L+P VEY + V+A   + +S P+     T +  P+GL F  +   S+++ W+      
Sbjct: 680  QELEPGVEYFIRVFAILENKKSIPVSARVATYLPAPEGLKFKSIKETSVEVEWDPLDIAF 739

Query: 1660 SRYRVTYSSP-EDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQ 1718
              + + + +  ++   E+  +    E +    GL PG EY +S+  + ++     L    
Sbjct: 740  ETWEIIFRNMNKEDEGEITKSLRRPETSYRQTGLAPGQEYEISLHIVKNNTRGPGLKRVT 799

Query: 1719 STAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVV 1778
            +T + AP+ ++   VT T+    W  P  ++ G  +    K+  G    I+L  D +   
Sbjct: 800  TTRLDAPSQIEVKDVTDTTALITWFKPLAEIDGIELTYGIKDVPGDRTTIDLTEDENQYS 859

Query: 1779 VSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKT 1838
            +  L   T+YEVS+ + +  ++S PA+   TT   +  PR  R    T+ +IT+ WR   
Sbjct: 860  IGNLKPDTEYEVSLISRRGDMSSNPAKETFTT--GLDAPRNLRRVSQTDNSITLEWRNGK 917

Query: 1839 ETITGFQVDAVPANG----QTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSP 1894
              I  +++   P +G    +  + ++ +   ++ T+TGL+PGT+Y I +  + ++  S+P
Sbjct: 918  AAIDSYRIKYAPISGGDHAEVDVPKSQQATTKT-TLTGLRPGTEYGIGVSAVKEDKESNP 976

Query: 1895 VVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKP-GSPPREVVPRPRP 1953
              I+A+T +D P +L+   T   SL + W+ P A+   Y + Y  P G      +PR   
Sbjct: 977  ATINAATELDTPKDLQVSETAETSLTLLWKTPLAKFDRYRLNYSLPTGQWVGVQLPR--- 1033

Query: 1954 GVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQKTPF----VTHPGYDTGNGI 2009
              T   + GLEPG EY + + A K   KS+P   +  T Q        VT  G+D   G+
Sbjct: 1034 NTTSYVLRGLEPGQEYNVLLTAEKGRHKSKPARVKASTEQAPELENLTVTEVGWD---GL 1090

Query: 2010 QLPGTSGQQPSV---------------------GQQMIFEEHGFRRTTPPTTA------- 2041
            +L  T+  Q                        G     +  G +  TP T +       
Sbjct: 1091 RLNWTAADQAYEHFIIQVQEANKVEAARNLTVPGSLRAVDIPGLKAATPYTVSIYGVIQG 1150

Query: 2042 --TPI--RHRPRPYPPNVGQEALSQT-----TISWAPFQDTSEYI-ISCHPVGTDEEPLQ 2091
              TP+          PN+G+  +++       ++W   +   EY  I      T E    
Sbjct: 1151 YRTPVLSAEASTGETPNLGEVVVAEVGWDALKLNWTAPEGAYEYFFIQVQEADTVEAAQN 1210

Query: 2092 FRVPGTSTSATLTGLTRGATYNIIVEALKDQ------QRHKVREEVVTVGN-SVNE---- 2140
              VPG   S  L GL     Y I +  +             + EEV  +GN +V E    
Sbjct: 1211 LTVPGGLRSTDLPGLKAATHYTITIRGVTQDFSTTPLSVEVLTEEVPDMGNLTVTEVSWD 1270

Query: 2141 --GLNQPTDDSCFDPYTV 2156
               LN  T D  +D +T+
Sbjct: 1271 ALRLNWTTPDGTYDQFTI 1288



 Score =  153 bits (386), Expect = 2e-36
 Identities = 147/662 (22%), Positives = 264/662 (39%), Gaps = 40/662 (6%)

Query: 628  IQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQY 687
            + W A   ++   ++++ +  N V   +  T+PG L +  I GL+    Y   +  + + 
Sbjct: 1365 LNWTAADNAY-EHFVIQVQEVNKVEAAQNLTLPGSLRAVDIPGLEAATPYRVSIYGVIR- 1422

Query: 688  GHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTV 747
            G++             TPV S   +    P       + +V++IT  SF +SW++     
Sbjct: 1423 GYR-------------TPVLSAEASTAKEP----EIGNLNVSDITPESFNLSWMATDGIF 1465

Query: 748  SGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQ 807
              F +E   S    E    ++     + +I  L P   +IV +  ++       I +T+ 
Sbjct: 1466 ETFTIEIIDSNRLLETVEYNISGAERTAHISGLPPSTDFIVYLSGLAPSIRTKTISATAT 1525

Query: 808  TTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEG-SSTELNLPETANSVT 866
            T A     + T+  ++     V W   +     + +    S +     E  L  T   + 
Sbjct: 1526 TEALPLLENLTISDINPYGFTVSWMASENAFDSFLVTVVDSGKLLDPQEFTLSGTQRKLE 1585

Query: 867  LSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIM 926
            L  L  G+ Y + +    +  ++ P+  +  T   P  D      +L   + T     + 
Sbjct: 1586 LRGLITGIGYEVMVSGFTQGHQTKPLRAEIVTEAEPEVD------NLLVSDATPDGFRLS 1639

Query: 927  WTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRES 986
            WT  E     + + +       E  +   ++     ++TGL     Y  +++ +S GR S
Sbjct: 1640 WTADEGVFDNFVLKIRDTKKQSEPLEITLLAPERTRDITGLREATEYEIELYGISKGRRS 1699

Query: 987  KPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGP 1046
            + ++A  TT + +P  + F + T+++  V W  P AQ+  +R+T      G P    V  
Sbjct: 1700 QTVSAIATTAMGSPKEVIFSDITENSATVSWRAPTAQVESFRITYVPITGGTPSMVTVDG 1759

Query: 1047 SVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVIT 1106
            + ++  L  L P  EY VS++A+KG +ES   +G FTT   G S       +T++  +  
Sbjct: 1760 TKTQTRLVKLIPGVEYLVSIIAMKGFEESEPVSGSFTTALDGPS-GLVTANITDSEALAR 1818

Query: 1107 WTPAPRI--GFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDA 1164
            W PA      + +     +  E  R V+ ++    ++ L P  EY   I     G ++ +
Sbjct: 1819 WQPAIATVDSYVISYTGEKVPEITRTVSGNTVEYALTDLEPATEYTLRI-FAEKGPQKSS 1877

Query: 1165 PIVNKVVTPLSPPTNL-HLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEE 1223
             I  K  T L  P +L   E   +T +LT  W R     +TGY +     +   G   E 
Sbjct: 1878 TITAKFTTDLDSPRDLTATEVQSETALLT--W-RPPRASVTGYLLVYESVD---GTVKEV 1931

Query: 1224 VVHADQSSCTFDNLSPGLEYNVSVYTVKDDKES---VPISDTIIPAVPPPTDLRFTNIGP 1280
            +V  D +S +  +LSP   Y   +  +     S     I  TI    P P D     +  
Sbjct: 1932 IVGPDTTSYSLADLSPSTHYTAKIQALNGPLRSNMIQTIFTTIGLLYPFPKDCSQAMLNG 1991

Query: 1281 DT 1282
            DT
Sbjct: 1992 DT 1993


>gi|157384973 tenascin R [Homo sapiens]
          Length = 1358

 Score =  353 bits (906), Expect = 1e-96
 Identities = 262/867 (30%), Positives = 409/867 (47%), Gaps = 52/867 (5%)

Query: 783  GRKYIVNVYQISEDGEQSLILSTSQTTAPD----APP-DPTVDQVDDTSIVVRWSRPQAP 837
            G++  +N        E+ L +       PD    APP D  V  + D SI + W  P A 
Sbjct: 293  GQRQCLNACSGRGQCEEGLCVCEEGYQGPDCSAVAPPEDLRVAGISDRSIELEWDGPMA- 351

Query: 838  ITGYRIVYSPSVEGS-STELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQ 896
            +T Y I Y P+  G    +  +P   + VT+++L+PG+ YNI++YAV  N  S P+  + 
Sbjct: 352  VTEYVISYQPTALGGLQLQQRVPGDWSGVTITELEPGLTYNISVYAVISNILSLPITAKV 411

Query: 897  ETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPI 956
             T        + +P+ LQF  +T+  V + W P   +  G+ +  IP N  G    ++P 
Sbjct: 412  AT-------HLSTPQGLQFKTITETTVEVQWEPFSFSFDGWEISFIPKNNEGGVIAQVPS 464

Query: 957  SRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVR 1016
               +F + TGL PG  Y   V A+     S P +A  +T +D PT +   + +D+   V 
Sbjct: 465  DVTSFNQ-TGLKPGEEYIVNVVALKEQARSPPTSASVSTVIDGPTQILVRDVSDTVAFVE 523

Query: 1017 WTPPRAQITGYRLTVGLT-RRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQES 1075
            W PPRA++    L  GL    G    + + P +S+Y ++ L+P S Y VS+ A++G  ES
Sbjct: 524  WIPPRAKVDFILLKYGLVGGEGGRTTFRLQPPLSQYSVQALRPGSRYEVSVSAVRGTNES 583

Query: 1076 PKATGVFTTLQPGSSIPPYNTEV---TETTIVITW--TPAPRIGFKLGVRPSQGGEAPRE 1130
              AT  FTT        P N  V   T T++ + W  + A    +K+ V  +  GE   E
Sbjct: 584  DSATTQFTT----EIDAPKNLRVGSRTATSLDLEWDNSEAEVQEYKV-VYSTLAGEQYHE 638

Query: 1131 VTSDSG-----SIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEAN 1185
            V    G        ++ L PG EY   I  + + Q+   P      T L  P +L + A+
Sbjct: 639  VLVPRGIGPTTRATLTDLVPGTEYGVGISAVMNSQQ-SVPATMNARTELDSPRDLMVTAS 697

Query: 1186 PDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNV 1245
             +T + ++ W +++ P I  YRIT TP++   G + E  V  D++S T  +L PG EY +
Sbjct: 698  SETSI-SLIWTKASGP-IDHYRITFTPSS---GIASEVTVPKDRTSYTLTDLEPGAEYII 752

Query: 1246 SVYTVKDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPV 1305
            SV   +  ++S+  +        P + L F+++   ++ +TW+  PS      ++ YSP 
Sbjct: 753  SVTAERGRQQSLESTVDAFTGFRPISHLHFSHVTSSSVNITWS-DPSPPADRLILNYSPR 811

Query: 1306 KNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGID 1365
              EE++ E+S+  +    VL  L P TEY+V++ +V+    S P+ G   TG+D P  I 
Sbjct: 812  DEEEEMMEVSLDATKRHAVLMGLQPATEYIVNLVAVHGTVTSEPIVGSITTGIDPPKDIT 871

Query: 1366 FSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYV 1425
             S++T +S  V W  P A+   YR+ + P    GR     VP++    T+T L P TEY 
Sbjct: 872  ISNVTKDSVMVSWSPPVASFDYYRVSYRPTQV-GRLDSSVVPNTVTEFTITRLNPATEYE 930

Query: 1426 VSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRI--TYG 1483
            +S+ ++ GREES  +     T  D P DL     TPT  L+ W AP   V  Y I  T+ 
Sbjct: 931  ISLNSVRGREESERICTLVHTAMDNPVDLIATNITPTEALLQWKAPVGEVENYVIVLTHF 990

Query: 1484 ETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEID 1543
               G    +   V G      +  L P   YT T+YA  G    P +S  IS N+ T +D
Sbjct: 991  AVAG----ETILVDGVSEEFRLVDLLPSTHYTATMYATNG----PLTSGTISTNFSTLLD 1042

Query: 1544 KPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQ 1603
             P+ +  ++V   S  + W P  + +  Y    T K+  G  K      + T + +EGL 
Sbjct: 1043 PPANLTASEVTRQSALISWQPPRAEIENY--VLTYKSTDGSRKELIVDAEDTWIRLEGLL 1100

Query: 1604 PTVEYVVSVYAQNPSGESQPLVQTAVT 1630
               +Y V + A   +  S  +  TA T
Sbjct: 1101 ENTDYTVLLQAAQDTTWSS-ITSTAFT 1126



 Score =  335 bits (860), Expect = 2e-91
 Identities = 238/812 (29%), Positives = 379/812 (46%), Gaps = 30/812 (3%)

Query: 1174 LSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCT 1233
            ++PP +L +    D  +  + W+      +T Y I+  PT    G  L++ V  D S  T
Sbjct: 326  VAPPEDLRVAGISDRSI-ELEWDGPMA--VTEYVISYQPT-ALGGLQLQQRVPGDWSGVT 381

Query: 1234 FDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSI 1293
               L PGL YN+SVY V  +  S+PI+  +   +  P  L+F  I   T+ V W P  S 
Sbjct: 382  ITELEPGLTYNISVYAVISNILSLPITAKVATHLSTPQGLQFKTITETTVEVQWEPF-SF 440

Query: 1294 DLTNFLVRYSPVKNEEDVAELSISPSD-NAVVLTNLLPGTEYVVSVSSVYEQHESTPLRG 1352
                + + + P  NE  V  ++  PSD  +   T L PG EY+V+V ++ EQ  S P   
Sbjct: 441  SFDGWEISFIPKNNEGGV--IAQVPSDVTSFNQTGLKPGEEYIVNVVALKEQARSPPTSA 498

Query: 1353 RQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNS 1412
               T +D PT I   D++     V WI PRA +    +++      G     R+    + 
Sbjct: 499  SVSTVIDGPTQILVRDVSDTVAFVEWIPPRAKVDFILLKYGLVGGEGGRTTFRLQPPLSQ 558

Query: 1413 ITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPA 1472
             ++  L PG+ Y VS+ A+ G  ES     Q +T  D P++L V + T TSL + WD   
Sbjct: 559  YSVQALRPGSRYEVSVSAVRGTNESDSATTQFTTEIDAPKNLRVGSRTATSLDLEWDNSE 618

Query: 1473 VTVRYYRITYGETGGNSPVQEFTVP---GSKSTATISGLKPGVDYTITVYAVTGRGDSPA 1529
              V+ Y++ Y    G     E  VP   G  + AT++ L PG +Y + + AV     +  
Sbjct: 619  AEVQEYKVVYSTLAGEQ-YHEVLVPRGIGPTTRATLTDLVPGTEYGVGISAVM----NSQ 673

Query: 1530 SSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKT 1589
             S P ++N RTE+D P  + VT   + SIS+ W  +S P+  YR+T TP +G       T
Sbjct: 674  QSVPATMNARTELDSPRDLMVTASSETSISLIWTKASGPIDHYRITFTPSSGIA--SEVT 731

Query: 1590 AGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIK 1649
               D+T  T+  L+P  EY++SV A+    +S      A T       L F+ V   S+ 
Sbjct: 732  VPKDRTSYTLTDLEPGAEYIISVTAERGRQQSLESTVDAFTGFRPISHLHFSHVTSSSVN 791

Query: 1650 IAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDM 1709
            I W  P     R  + YS  ++    +  + D  +  A L GL+P +EY V++VA+H  +
Sbjct: 792  ITWSDPSPPADRLILNYSPRDEEEEMMEVSLDATKRHAVLMGLQPATEYIVNLVAVHGTV 851

Query: 1710 ESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEIN 1769
             S+P++G+ +T I  P D+  + VT  S+   W+PP      YRV   P +  G +    
Sbjct: 852  TSEPIVGSITTGIDPPKDITISNVTKDSVMVSWSPPVASFDYYRVSYRPTQ-VGRLDSSV 910

Query: 1770 LAPDSSSVVVSGLMVATKYEVSVYALKDTLTS-RPAQGVVTTLENVSPPRRARVTDATET 1828
            +    +   ++ L  AT+YE+S+ +++    S R    V T ++N   P     T+ T T
Sbjct: 911  VPNTVTEFTITRLNPATEYEISLNSVRGREESERICTLVHTAMDN---PVDLIATNITPT 967

Query: 1829 TITISWRTKTETITGFQV--DAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTL 1886
               + W+     +  + +        G+T +   +  + R   +  L P T Y   +Y  
Sbjct: 968  EALLQWKAPVGEVENYVIVLTHFAVAGETILVDGVSEEFR---LVDLLPSTHYTATMYAT 1024

Query: 1887 NDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPRE 1946
            N    S  +  + ST +D P+NL     T  S L+SWQPPRA I  Y++ Y+      +E
Sbjct: 1025 NGPLTSGTISTNFSTLLDPPANLTASEVTRQSALISWQPPRAEIENYVLTYKSTDGSRKE 1084

Query: 1947 VVPRPRPGVTEATITGLEPGTEYTIYVIALKN 1978
            ++       T   + GL   T+YT+ + A ++
Sbjct: 1085 LIVDAED--TWIRLEGLLENTDYTVLLQAAQD 1114



 Score =  274 bits (700), Expect = 8e-73
 Identities = 208/812 (25%), Positives = 357/812 (43%), Gaps = 24/812 (2%)

Query: 902  PRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTF 961
            P    V  P DL+   ++D  + + W  P  AVT Y +   P  L G   Q+      + 
Sbjct: 321  PDCSAVAPPEDLRVAGISDRSIELEWDGP-MAVTEYVISYQPTALGGLQLQQRVPGDWSG 379

Query: 962  AEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPR 1021
              +T L PG+TY   V+AV     S P+TA+  T L  P  LQF   T++TV V+W P  
Sbjct: 380  VTITELEPGLTYNISVYAVISNILSLPITAKVATHLSTPQGLQFKTITETTVEVQWEPFS 439

Query: 1022 AQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGV 1081
                G+ ++             V   V+ +    L+P  EY V++VA+K    SP  +  
Sbjct: 440  FSFDGWEISFIPKNNEGGVIAQVPSDVTSFNQTGLKPGEEYIVNVVALKEQARSPPTSAS 499

Query: 1082 FTTLQPGSSIPPYNTEVTETTIVITWTPAPR-----IGFKLGVRPSQGGEAPREVTSDSG 1136
             +T+  G +      +V++T   + W P PR     I  K G+   +GG     +     
Sbjct: 500  VSTVIDGPT-QILVRDVSDTVAFVEWIP-PRAKVDFILLKYGLVGGEGGRTTFRLQPPLS 557

Query: 1137 SIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWE 1196
               V  L PG  Y  ++  +R   E D+    +  T +  P NL + +   T  L + W+
Sbjct: 558  QYSVQALRPGSRYEVSVSAVRGTNESDS-ATTQFTTEIDAPKNLRVGSRTATS-LDLEWD 615

Query: 1197 RSTTPDITGYRITTTPTNGQQGNS-LEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKE 1255
             S   ++  Y++  +   G+Q +  L        +  T  +L PG EY V +  V + ++
Sbjct: 616  NSEA-EVQEYKVVYSTLAGEQYHEVLVPRGIGPTTRATLTDLVPGTEYGVGISAVMNSQQ 674

Query: 1256 SVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELS 1315
            SVP +      +  P DL  T     ++ + W    S  + ++ + ++P  +    +E++
Sbjct: 675  SVPATMNARTELDSPRDLMVTASSETSISLIWT-KASGPIDHYRITFTP--SSGIASEVT 731

Query: 1316 ISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFT 1375
            +     +  LT+L PG EY++SV++   + +S        TG    + + FS +T++S  
Sbjct: 732  VPKDRTSYTLTDLEPGAEYIISVTAERGRQQSLESTVDAFTGFRPISHLHFSHVTSSSVN 791

Query: 1376 VHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGRE 1435
            + W  P        + + P        E  +  ++    L  L P TEY+V++VA++G  
Sbjct: 792  ITWSDPSPPADRLILNYSPRDEEEEMMEVSLDATKRHAVLMGLQPATEYIVNLVAVHGTV 851

Query: 1436 ESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFT 1495
             S  ++G  +T  D P+D+ +   T  S+++SW  P  +  YYR++Y  T     +    
Sbjct: 852  TSEPIVGSITTGIDPPKDITISNVTKDSVMVSWSPPVASFDYYRVSYRPTQVGR-LDSSV 910

Query: 1496 VPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQD 1555
            VP + +  TI+ L P  +Y I++ +V GR +    S+ I     T +D P  +  T++  
Sbjct: 911  VPNTVTEFTITRLNPATEYEISLNSVRGREE----SERICTLVHTAMDNPVDLIATNITP 966

Query: 1556 NSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQ 1615
                ++W      V  Y +  T     G  +T        E  +  L P+  Y  ++YA 
Sbjct: 967  TEALLQWKAPVGEVENYVIVLTHFAVAG--ETILVDGVSEEFRLVDLLPSTHYTATMYAT 1024

Query: 1616 NPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHE 1675
            N    S  +     T +D P  L  ++V   S  I+W+ P+ ++  Y +TY S +    E
Sbjct: 1025 NGPLTSGTISTNFSTLLDPPANLTASEVTRQSALISWQPPRAEIENYVLTYKSTDGSRKE 1084

Query: 1676 LFPAPDGEEDTAELQGLRPGSEYTVSVVALHD 1707
            L    D E+    L+GL   ++YTV + A  D
Sbjct: 1085 LI--VDAEDTWIRLEGLLENTDYTVLLQAAQD 1114



 Score =  254 bits (650), Expect = 5e-67
 Identities = 219/824 (26%), Positives = 351/824 (42%), Gaps = 26/824 (3%)

Query: 1000 PTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPR-QYNVGPSVSKYPLRNLQP 1058
            P +L+    +D ++ + W  P A +T Y ++   T  G  + Q  V    S   +  L+P
Sbjct: 329  PEDLRVAGISDRSIELEWDGPMA-VTEYVISYQPTALGGLQLQQRVPGDWSGVTITELEP 387

Query: 1059 ASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRI--GFK 1116
               Y +S+ A+  N  S   T    T         + T +TETT+ + W P      G++
Sbjct: 388  GLTYNISVYAVISNILSLPITAKVATHLSTPQGLQFKT-ITETTVEVQWEPFSFSFDGWE 446

Query: 1117 LGVRPSQG-GEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLS 1175
            +   P    G    +V SD  S   +GL PG EY+  +  L++ Q R  P    V T + 
Sbjct: 447  ISFIPKNNEGGVIAQVPSDVTSFNQTGLKPGEEYIVNVVALKE-QARSPPTSASVSTVID 505

Query: 1176 PPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFD 1235
             PT + +    DT V  V W          + +      G +G      +    S  +  
Sbjct: 506  GPTQILVRDVSDT-VAFVEWIPPRAK--VDFILLKYGLVGGEGGRTTFRLQPPLSQYSVQ 562

Query: 1236 NLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDL 1295
             L PG  Y VSV  V+   ES   +      +  P +LR  +    ++ + W    + ++
Sbjct: 563  ALRPGSRYEVSVSAVRGTNESDSATTQFTTEIDAPKNLRVGSRTATSLDLEWDNSEA-EV 621

Query: 1296 TNFLVRYSPVKNE---EDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRG 1352
              + V YS +  E   E +    I P+  A  LT+L+PGTEY V +S+V    +S P   
Sbjct: 622  QEYKVVYSTLAGEQYHEVLVPRGIGPTTRAT-LTDLVPGTEYGVGISAVMNSQQSVPATM 680

Query: 1353 RQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNS 1412
              +T LDSP  +  +  +  S ++ W      I  YRI   P   SG   E  VP  R S
Sbjct: 681  NARTELDSPRDLMVTASSETSISLIWTKASGPIDHYRITFTPS--SGIASEVTVPKDRTS 738

Query: 1413 ITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPA 1472
             TLT+L PG EY++S+ A  GR++S        T       L     T +S+ I+W  P+
Sbjct: 739  YTLTDLEPGAEYIISVTAERGRQQSLESTVDAFTGFRPISHLHFSHVTSSSVNITWSDPS 798

Query: 1473 VTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSK 1532
                   + Y        + E ++  +K  A + GL+P  +Y + + AV G      +S+
Sbjct: 799  PPADRLILNYSPRDEEEEMMEVSLDATKRHAVLMGLQPATEYIVNLVAVHGT----VTSE 854

Query: 1533 PISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGP 1592
            PI  +  T ID P  + +++V  +S+ V W P  +    YRV+  P    G   +     
Sbjct: 855  PIVGSITTGIDPPKDITISNVTKDSVMVSWSPPVASFDYYRVSYRPTQ-VGRLDSSVVPN 913

Query: 1593 DQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAW 1652
              TE TI  L P  EY +S+ +     ES+ +     T +D P  L  T++      + W
Sbjct: 914  TVTEFTITRLNPATEYEISLNSVRGREESERICTLVHTAMDNPVDLIATNITPTEALLQW 973

Query: 1653 ESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQ 1712
            ++P G+V  Y +  +        +    DG  +   L  L P + YT ++ A +  + S 
Sbjct: 974  KAPVGEVENYVIVLTHFAVAGETILV--DGVSEEFRLVDLLPSTHYTATMYATNGPLTSG 1031

Query: 1713 PLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAP 1772
             +    ST +  P +L  ++VT  S    W PP  ++  Y +  T K   G  KE+ +  
Sbjct: 1032 TISTNFSTLLDPPANLTASEVTRQSALISWQPPRAEIENYVL--TYKSTDGSRKELIVDA 1089

Query: 1773 DSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSP 1816
            + + + + GL+  T Y V + A +DT  S       TT   V P
Sbjct: 1090 EDTWIRLEGLLENTDYTVLLQAAQDTTWSSITSTAFTTGGRVFP 1133



 Score =  245 bits (626), Expect = 3e-64
 Identities = 215/816 (26%), Positives = 355/816 (43%), Gaps = 61/816 (7%)

Query: 628  IQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQY 687
            ++W+ P    +++Y++ ++P    G   +  +PG  +  TI  L+PG+ Y          
Sbjct: 344  LEWDGPMA--VTEYVISYQPTALGGLQLQQRVPGDWSGVTITELEPGLTY---------- 391

Query: 688  GHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTV 747
                ++ +   +   S P+T+   T  +TP      T      IT ++  V W   S + 
Sbjct: 392  ---NISVYAVISNILSLPITAKVATHLSTPQGLQFKT------ITETTVEVQWEPFSFSF 442

Query: 748  SGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQ 807
             G+ + + + +  +      +PS  TS N   L PG +YIVNV  + E   +S   S S 
Sbjct: 443  DGWEISF-IPKNNEGGVIAQVPSDVTSFNQTGLKPGEEYIVNVVALKEQA-RSPPTSASV 500

Query: 808  TTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYS-PSVEGSSTELNLPETANSVT 866
            +T  D P    V  V DT   V W  P+A +    + Y     EG  T   L    +  +
Sbjct: 501  STVIDGPTQILVRDVSDTVAFVEWIPPRAKVDFILLKYGLVGGEGGRTTFRLQPPLSQYS 560

Query: 867  LSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIM 926
            +  L+PG +Y +++ AV    ES     Q  T        + +P++L+    T   + + 
Sbjct: 561  VQALRPGSRYEVSVSAVRGTNESDSATTQFTT-------EIDAPKNLRVGSRTATSLDLE 613

Query: 927  WTPPESAVTGYRVDVIPVNLPGEHGQRLPISR----NTFAEVTGLSPGVTYYFKVFAVSH 982
            W   E+ V  Y+  V+   L GE    + + R     T A +T L PG  Y   + AV +
Sbjct: 614  WDNSEAEVQEYK--VVYSTLAGEQYHEVLVPRGIGPTTRATLTDLVPGTEYGVGISAVMN 671

Query: 983  GRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQY 1042
             ++S P T    T+LD+P +L     +++++ + WT     I  YR+T      G   + 
Sbjct: 672  SQQSVPATMNARTELDSPRDLMVTASSETSISLIWTKASGPIDHYRITF-TPSSGIASEV 730

Query: 1043 NVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKAT-GVFTTLQPGSSIPPYNTEVTET 1101
             V    + Y L +L+P +EY +S+ A +G Q+S ++T   FT  +P S +  + + VT +
Sbjct: 731  TVPKDRTSYTLTDLEPGAEYIISVTAERGRQQSLESTVDAFTGFRPISHL--HFSHVTSS 788

Query: 1102 TIVITWT----PAPRIGFKLGVRPSQGGEAPREVTSDSGS--IVVSGLTPGVEYVYTIQV 1155
            ++ ITW+    PA R+   L   P    E   EV+ D+     V+ GL P  EY+  + V
Sbjct: 789  SVNITWSDPSPPADRL--ILNYSPRDEEEEMMEVSLDATKRHAVLMGLQPATEYIVNL-V 845

Query: 1156 LRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNG 1215
               G     PIV  + T + PP ++ + +N     + VSW          YR++  PT  
Sbjct: 846  AVHGTVTSEPIVGSITTGIDPPKDITI-SNVTKDSVMVSWS-PPVASFDYYRVSYRPT-- 901

Query: 1216 QQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRF 1275
            Q G     VV    +  T   L+P  EY +S+ +V+  +ES  I   +  A+  P DL  
Sbjct: 902  QVGRLDSSVVPNTVTEFTITRLNPATEYEISLNSVRGREESERICTLVHTAMDNPVDLIA 961

Query: 1276 TNIGPDTMRVTW-APPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEY 1334
            TNI P    + W AP   ++    ++ +  V  E     + +        L +LLP T Y
Sbjct: 962  TNITPTEALLQWKAPVGEVENYVIVLTHFAVAGE----TILVDGVSEEFRLVDLLPSTHY 1017

Query: 1335 VVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHP 1394
              ++ +      S  +     T LD P  +  S++T  S  + W  PRA I  Y + +  
Sbjct: 1018 TATMYATNGPLTSGTISTNFSTLLDPPANLTASEVTRQSALISWQPPRAEIENYVLTY-- 1075

Query: 1395 EHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVA 1430
            +   G  +E  V      I L  L   T+Y V + A
Sbjct: 1076 KSTDGSRKELIVDAEDTWIRLEGLLENTDYTVLLQA 1111



 Score =  244 bits (622), Expect = 9e-64
 Identities = 176/651 (27%), Positives = 293/651 (45%), Gaps = 18/651 (2%)

Query: 1351 RGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSR 1410
            +G   + +  P  +  + I+  S  + W  P A +T Y I + P    G   + RVP   
Sbjct: 319  QGPDCSAVAPPEDLRVAGISDRSIELEWDGPMA-VTEYVISYQPTALGGLQLQQRVPGDW 377

Query: 1411 NSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDA 1470
            + +T+T L PG  Y +S+ A+     S  +  + +T    P+ L+    T T++ + W+ 
Sbjct: 378  SGVTITELEPGLTYNISVYAVISNILSLPITAKVATHLSTPQGLQFKTITETTVEVQWEP 437

Query: 1471 PAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPAS 1530
             + +   + I++        V    VP   ++   +GLKPG +Y + V A+  +  SP +
Sbjct: 438  FSFSFDGWEISFIPKNNEGGVIA-QVPSDVTSFNQTGLKPGEEYIVNVVALKEQARSPPT 496

Query: 1531 SKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTA 1590
            S  +S    T ID P+Q+ V DV D    V+W+P  + V    +      G G   T   
Sbjct: 497  SASVS----TVIDGPTQILVRDVSDTVAFVEWIPPRAKVDFILLKYGLVGGEGGRTTFRL 552

Query: 1591 GPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKI 1650
             P  ++ +++ L+P   Y VSV A   + ES        T ID PK L        S+ +
Sbjct: 553  QPPLSQYSVQALRPGSRYEVSVSAVRGTNESDSATTQFTTEIDAPKNLRVGSRTATSLDL 612

Query: 1651 AWESPQGQVSRYRVTYSS-PEDGIHE-LFPAPDGEEDTAELQGLRPGSEYTVSVVALHDD 1708
             W++ + +V  Y+V YS+   +  HE L P   G    A L  L PG+EY V + A+ + 
Sbjct: 613  EWDNSEAEVQEYKVVYSTLAGEQYHEVLVPRGIGPTTRATLTDLVPGTEYGVGISAVMNS 672

Query: 1709 MESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEI 1768
             +S P      T + +P DL  T  + TS+S  WT  +  +  YR+  TP   +G   E+
Sbjct: 673  QQSVPATMNARTELDSPRDLMVTASSETSISLIWTKASGPIDHYRITFTPS--SGIASEV 730

Query: 1769 NLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATET 1828
             +  D +S  ++ L    +Y +SV A +    S   +  V       P      +  T +
Sbjct: 731  TVPKDRTSYTLTDLEPGAEYIISVTAERGRQQS--LESTVDAFTGFRPISHLHFSHVTSS 788

Query: 1829 TITISWRTKTETITGFQVDAVPANGQTPIQR-TIKPDVRSYTITGLQPGTDYKIYLYTLN 1887
            ++ I+W   +       ++  P + +  +   ++    R   + GLQP T+Y + L  ++
Sbjct: 789  SVNITWSDPSPPADRLILNYSPRDEEEEMMEVSLDATKRHAVLMGLQPATEYIVNLVAVH 848

Query: 1888 DNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYE--KPGSPPR 1945
                S P+V   +T ID P ++     T +S++VSW PP A    Y + Y   + G    
Sbjct: 849  GTVTSEPIVGSITTGIDPPKDITISNVTKDSVMVSWSPPVASFDYYRVSYRPTQVGRLDS 908

Query: 1946 EVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQKTP 1996
             VVP     VTE TIT L P TEY I + +++  ++SE +     T    P
Sbjct: 909  SVVPNT---VTEFTITRLNPATEYEISLNSVRGREESERICTLVHTAMDNP 956



 Score =  166 bits (421), Expect = 2e-40
 Identities = 159/647 (24%), Positives = 273/647 (42%), Gaps = 42/647 (6%)

Query: 610  GPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIK 669
            GP ++ + +         ++W  P+ + +   +L++      G      +   L+ Y+++
Sbjct: 506  GPTQILVRDVSDTVAF--VEWIPPR-AKVDFILLKYGLVGGEGGRTTFRLQPPLSQYSVQ 562

Query: 670  GLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVT 729
             L+PG  YE  + +++     +     FTT         N   G  T  S  +    S  
Sbjct: 563  ALRPGSRYEVSVSAVRGTNESDSATTQFTT---EIDAPKNLRVGSRTATSLDLEWDNSEA 619

Query: 730  EITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVN 789
            E+     V S      T++G +    L   G  P         T   + DL+PG +Y V 
Sbjct: 620  EVQEYKVVYS------TLAGEQYHEVLVPRGIGP--------TTRATLTDLVPGTEYGVG 665

Query: 790  VYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSV 849
            +  +  + +QS+  + +  T  D+P D  V    +TSI + W++   PI  YRI ++PS 
Sbjct: 666  ISAVM-NSQQSVPATMNARTELDSPRDLMVTASSETSISLIWTKASGPIDHYRITFTPS- 723

Query: 850  EGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPS 909
             G ++E+ +P+   S TL+DL+PG +Y I++ A    Q+S    +   T   P S     
Sbjct: 724  SGIASEVTVPKDRTSYTLTDLEPGAEYIISVTAERGRQQSLESTVDAFTGFRPISH---- 779

Query: 910  PRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSP 969
               L F  VT   V I W+ P        ++  P +   E  +    +    A + GL P
Sbjct: 780  ---LHFSHVTSSSVNITWSDPSPPADRLILNYSPRDEEEEMMEVSLDATKRHAVLMGLQP 836

Query: 970  GVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRL 1029
               Y   + AV     S+P+    TT +D P ++   N T  +V+V W+PP A    YR+
Sbjct: 837  ATEYIVNLVAVHGTVTSEPIVGSITTGIDPPKDITISNVTKDSVMVSWSPPVASFDYYRV 896

Query: 1030 TVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPK-ATGVFTTLQPG 1088
            +   T+ G+     V  +V+++ +  L PA+EY +SL +++G +ES +  T V T +   
Sbjct: 897  SYRPTQVGRLDSSVVPNTVTEFTITRLNPATEYEISLNSVRGREESERICTLVHTAMD-- 954

Query: 1089 SSIPPYNTEVTETTIVITW-TPAPRIGFKLGVRP--SQGGEAPREVTSDSGSIVVSGLTP 1145
            + +    T +T T  ++ W  P   +   + V    +  GE    V   S    +  L P
Sbjct: 955  NPVDLIATNITPTEALLQWKAPVGEVENYVIVLTHFAVAGETIL-VDGVSEEFRLVDLLP 1013

Query: 1146 GVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITG 1205
               Y  T+    +G      I     T L PP NL          L +SW+     +I  
Sbjct: 1014 STHYTATMYA-TNGPLTSGTISTNFSTLLDPPANLTASEVTRQSAL-ISWQ-PPRAEIEN 1070

Query: 1206 YRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKD 1252
            Y +T   T+G +    E +V A+ +    + L    +Y V +   +D
Sbjct: 1071 YVLTYKSTDGSR---KELIVDAEDTWIRLEGLLENTDYTVLLQAAQD 1114



 Score =  131 bits (330), Expect = 7e-30
 Identities = 77/296 (26%), Positives = 136/296 (45%), Gaps = 3/296 (1%)

Query: 1716 GTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSS 1775
            G   +A+  P DL+   ++  S+  +W  P + +T Y +   P    G   +  +  D S
Sbjct: 320  GPDCSAVAPPEDLRVAGISDRSIELEWDGP-MAVTEYVISYQPTALGGLQLQQRVPGDWS 378

Query: 1776 SVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWR 1835
             V ++ L     Y +SVYA+   + S P    V T  ++S P+  +    TETT+ + W 
Sbjct: 379  GVTITELEPGLTYNISVYAVISNILSLPITAKVAT--HLSTPQGLQFKTITETTVEVQWE 436

Query: 1836 TKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPV 1895
              + +  G+++  +P N +  +   +  DV S+  TGL+PG +Y + +  L + ARS P 
Sbjct: 437  PFSFSFDGWEISFIPKNNEGGVIAQVPSDVTSFNQTGLKPGEEYIVNVVALKEQARSPPT 496

Query: 1896 VIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGV 1955
                ST ID P+ +     +     V W PPRA++   ++KY   G        R +P +
Sbjct: 497  SASVSTVIDGPTQILVRDVSDTVAFVEWIPPRAKVDFILLKYGLVGGEGGRTTFRLQPPL 556

Query: 1956 TEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQKTPFVTHPGYDTGNGIQL 2011
            ++ ++  L PG+ Y + V A++   +S+    +  T    P     G  T   + L
Sbjct: 557  SQYSVQALRPGSRYEVSVSAVRGTNESDSATTQFTTEIDAPKNLRVGSRTATSLDL 612



 Score = 46.6 bits (109), Expect = 3e-04
 Identities = 57/225 (25%), Positives = 84/225 (37%), Gaps = 57/225 (25%)

Query: 1901 TAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATI 1960
            +A+  P +LR    +  S+ + W  P A +T Y+I Y+       ++  R     +  TI
Sbjct: 324  SAVAPPEDLRVAGISDRSIELEWDGPMA-VTEYVISYQPTALGGLQLQQRVPGDWSGVTI 382

Query: 1961 TGLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQKTPFVTHPGYDTGNGIQLPGTSGQQPS 2020
            T LEPG  Y I V A+ +N  S P+  +          TH    T  G+Q          
Sbjct: 383  TELEPGLTYNISVYAVISNILSLPITAK--------VATH--LSTPQGLQF--------- 423

Query: 2021 VGQQMIFEEHGFRRTTPPTTATPIRHRPRPYPPNVGQEALSQTTISWAPFQDTSE-YIIS 2079
                         +T   TT                        + W PF  + + + IS
Sbjct: 424  -------------KTITETTVE----------------------VQWEPFSFSFDGWEIS 448

Query: 2080 CHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQR 2124
              P   +E  +  +VP   TS   TGL  G  Y + V ALK+Q R
Sbjct: 449  FIPKN-NEGGVIAQVPSDVTSFNQTGLKPGEEYIVNVVALKEQAR 492


>gi|62988324 tenascin N [Homo sapiens]
          Length = 1299

 Score =  315 bits (807), Expect = 3e-85
 Identities = 240/820 (29%), Positives = 382/820 (46%), Gaps = 28/820 (3%)

Query: 1177 PTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDN 1236
            P  L L  N +  +L VSWE S+  D   Y ++  P  G++ +  +  V  +Q S     
Sbjct: 265  PQGLQLLKNTEDSLL-VSWEPSSQVD--HYLLSYYPL-GKELSGKQIQVPKEQHSYEILG 320

Query: 1237 LSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLT 1296
            L PG +Y V++  VK++  S P        +        T+   +++ V W  P S ++ 
Sbjct: 321  LLPGTKYIVTLRNVKNEVSSSPQHLLATTDLAVLGTAWVTDETENSLDVEWENP-STEVD 379

Query: 1297 NFLVRYSPVKNEEDVAELSISPSDNAVV---LTNLLPGTEYVVSVSSVYEQHESTPLRGR 1353
             + +RY P+  +E VAE+++  S +      +T L PGTEY ++V  +  + E  P+   
Sbjct: 380  YYKLRYGPMTGQE-VAEVTVPKSSDPKSRYDITGLHPGTEYKITVVPMRGELEGKPILLN 438

Query: 1354 QKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSI 1413
             +T +DSPT +    +T ++ TV W   +A I  Y +R+      G  +E  V    +S 
Sbjct: 439  GRTEIDSPTNVVTDRVTEDTATVSWDPVQAVIDKYVVRYTSA--DGDTKEMAVHKDESST 496

Query: 1414 TLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAV 1473
             LT L PG  Y V + A  G + S        T  D P +L     T  +  ISWD    
Sbjct: 497  VLTGLKPGEAYKVYVWAERGNQGSKKADTNALTEIDSPANLVTDRVTENTATISWDPVQA 556

Query: 1474 TVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKP 1533
            T+  Y + Y  +  +   +E  V   +S+  ++GL+PGV+YT+ V+A  G  +S    K 
Sbjct: 557  TIDKYVVRY-TSADDQETREVLVGKEQSSTVLTGLRPGVEYTVHVWAQKGDRES----KK 611

Query: 1534 ISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPD 1593
               N  T+ID P  +    V +N  +V W P  + +  Y V  T  +  G T+    G +
Sbjct: 612  ADTNAPTDIDSPKNLVTDRVTENMATVSWDPVQAAIDKYVVRYT--SAGGETREVPVGKE 669

Query: 1594 QTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWE 1653
            Q+   + GL+P +EY+V V+AQ    ES+     A T+ID P+ L    V  +   ++W+
Sbjct: 670  QSSTVLTGLRPGMEYMVHVWAQKGDQESKKADTKAQTDIDSPQNLVTDRVTENMATVSWD 729

Query: 1654 SPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAE-LQGLRPGSEYTVSVVALHDDMESQ 1712
              +  + RY V Y+S +DG  E    P G+E ++  L GLRPG EYTV V A     ES+
Sbjct: 730  PVRATIDRYVVRYTSAKDG--ETREVPVGKEQSSTVLTGLRPGVEYTVHVWAQKGAQESK 787

Query: 1713 PLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAP 1772
                   T I +P +L    VT  + +  W P    +  Y V  T     G  +E+ +  
Sbjct: 788  KADTKAQTDIDSPQNLVTDWVTENTATVSWDPVQATIDRYVVHYT--SANGETREVPVGK 845

Query: 1773 DSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITI 1832
            + SS V++GL    +Y V V+A K    S+ A     T   +  P+       TE   T+
Sbjct: 846  EQSSTVLTGLRPGMEYTVHVWAQKGNQESKKADTKAQT--EIDGPKNLVTDWVTENMATV 903

Query: 1833 SWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARS 1892
            SW     TI  + V    A+G+T  +  +  +  S  +TGL+PG +Y ++++       S
Sbjct: 904  SWDPVQATIDKYMVRYTSADGETR-EVPVGKEHSSTVLTGLRPGMEYMVHVWAQKGAQES 962

Query: 1893 SPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPR 1952
                  A T +D P NLR  A T +  +++W PP A+I GYI+ Y+ P    +E+     
Sbjct: 963  KKADTKAQTELDPPRNLRPSAVTQSGGILTWTPPSAQIHGYILTYQFPDGTVKEMQLGRE 1022

Query: 1953 PGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTV 1992
                   + GLE G  Y + ++A K  ++S  +     TV
Sbjct: 1023 D--QRFALQGLEQGATYPVSLVAFKGGRRSRNVSTTLSTV 1060



 Score =  313 bits (801), Expect = 2e-84
 Identities = 222/747 (29%), Positives = 346/747 (46%), Gaps = 25/747 (3%)

Query: 1267 VPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLT 1326
            V  P  L+      D++ V+W P   +D  ++L+ Y P+  E    ++ +    ++  + 
Sbjct: 262  VVTPQGLQLLKNTEDSLLVSWEPSSQVD--HYLLSYYPLGKELSGKQIQVPKEQHSYEIL 319

Query: 1327 NLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATIT 1386
             LLPGT+Y+V++ +V  +  S+P      T L        +D T NS  V W  P   + 
Sbjct: 320  GLLPGTKYIVTLRNVKNEVSSSPQHLLATTDLAVLGTAWVTDETENSLDVEWENPSTEVD 379

Query: 1387 GYRIRHHPEHFSGRP-REDRVPHS---RNSITLTNLTPGTEYVVSIVALNGREESPLLIG 1442
             Y++R+ P   +G+   E  VP S   ++   +T L PGTEY +++V + G  E   ++ 
Sbjct: 380  YYKLRYGP--MTGQEVAEVTVPKSSDPKSRYDITGLHPGTEYKITVVPMRGELEGKPILL 437

Query: 1443 QQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKST 1502
               T  D P ++     T  +  +SWD     +  Y + Y    G++  +E  V   +S+
Sbjct: 438  NGRTEIDSPTNVVTDRVTEDTATVSWDPVQAVIDKYVVRYTSADGDT--KEMAVHKDESS 495

Query: 1503 ATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKW 1562
              ++GLKPG  Y + V+A  G       SK    N  TEID P+ +    V +N+ ++ W
Sbjct: 496  TVLTGLKPGEAYKVYVWAERGN----QGSKKADTNALTEIDSPANLVTDRVTENTATISW 551

Query: 1563 LPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQ 1622
             P  + +  Y V  T  +    T+    G +Q+   + GL+P VEY V V+AQ    ES+
Sbjct: 552  DPVQATIDKYVVRYTSADDQ-ETREVLVGKEQSSTVLTGLRPGVEYTVHVWAQKGDRESK 610

Query: 1623 PLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDG 1682
                 A T+ID PK L    V  +   ++W+  Q  + +Y V Y+S      E+   P G
Sbjct: 611  KADTNAPTDIDSPKNLVTDRVTENMATVSWDPVQAAIDKYVVRYTSAGGETREV---PVG 667

Query: 1683 EEDTAE-LQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQ 1741
            +E ++  L GLRPG EY V V A   D ES+       T I +P +L   +VT    +  
Sbjct: 668  KEQSSTVLTGLRPGMEYMVHVWAQKGDQESKKADTKAQTDIDSPQNLVTDRVTENMATVS 727

Query: 1742 WTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTS 1801
            W P    +  Y VR T   K G  +E+ +  + SS V++GL    +Y V V+A K    S
Sbjct: 728  WDPVRATIDRYVVRYT-SAKDGETREVPVGKEQSSTVLTGLRPGVEYTVHVWAQKGAQES 786

Query: 1802 RPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTI 1861
            + A     T  ++  P+       TE T T+SW     TI  + V    ANG+T  +  +
Sbjct: 787  KKADTKAQT--DIDSPQNLVTDWVTENTATVSWDPVQATIDRYVVHYTSANGETR-EVPV 843

Query: 1862 KPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLV 1921
              +  S  +TGL+PG +Y ++++    N  S      A T ID P NL     T N   V
Sbjct: 844  GKEQSSTVLTGLRPGMEYTVHVWAQKGNQESKKADTKAQTEIDGPKNLVTDWVTENMATV 903

Query: 1922 SWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQK 1981
            SW P +A I  Y+++Y       REV        T   +TGL PG EY ++V A K  Q+
Sbjct: 904  SWDPVQATIDKYMVRYTSADGETREVPVGKEHSST--VLTGLRPGMEYMVHVWAQKGAQE 961

Query: 1982 SEPLIGRKKTVQKTPFVTHPGYDTGNG 2008
            S+    + +T    P    P   T +G
Sbjct: 962  SKKADTKAQTELDPPRNLRPSAVTQSG 988



 Score =  304 bits (778), Expect = 8e-82
 Identities = 240/848 (28%), Positives = 381/848 (44%), Gaps = 35/848 (4%)

Query: 907  VPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVN--LPGEHGQRLPISRNTFAEV 964
            V +P+ LQ ++ T+  + + W P  S V  Y +   P+   L G+  Q +P  ++++ E+
Sbjct: 262  VVTPQGLQLLKNTEDSLLVSWEP-SSQVDHYLLSYYPLGKELSGKQIQ-VPKEQHSY-EI 318

Query: 965  TGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQI 1024
             GL PG  Y   +  V +   S P     TT L         +ET++++ V W  P  ++
Sbjct: 319  LGLLPGTKYIVTLRNVKNEVSSSPQHLLATTDLAVLGTAWVTDETENSLDVEWENPSTEV 378

Query: 1025 TGYRLTVGLTRRGQPRQYNVGPS---VSKYPLRNLQPASEYTVSLVAIKGNQE-SPKATG 1080
              Y+L  G     +  +  V  S    S+Y +  L P +EY +++V ++G  E  P    
Sbjct: 379  DYYKLRYGPMTGQEVAEVTVPKSSDPKSRYDITGLHPGTEYKITVVPMRGELEGKPILLN 438

Query: 1081 VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVR--PSQGGEAPREVTSDSGSI 1138
              T +   +++      VTE T  ++W P   +  K  VR   + G      V  D  S 
Sbjct: 439  GRTEIDSPTNV--VTDRVTEDTATVSWDPVQAVIDKYVVRYTSADGDTKEMAVHKDESST 496

Query: 1139 VVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERS 1198
            V++GL PG  Y   +   R  Q       N  +T +  P NL  +   +    T+SW+  
Sbjct: 497  VLTGLKPGEAYKVYVWAERGNQGSKKADTN-ALTEIDSPANLVTDRVTE-NTATISWD-P 553

Query: 1199 TTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVP 1258
                I  Y +  T  + Q+  + E +V  +QSS     L PG+EY V V+  K D+ES  
Sbjct: 554  VQATIDKYVVRYTSADDQE--TREVLVGKEQSSTVLTGLRPGVEYTVHVWAQKGDRESKK 611

Query: 1259 ISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISP 1318
                    +  P +L    +  +   V+W P  +  +  ++VRY+    E    E+ +  
Sbjct: 612  ADTNAPTDIDSPKNLVTDRVTENMATVSWDPVQAA-IDKYVVRYTSAGGE--TREVPVGK 668

Query: 1319 SDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHW 1378
              ++ VLT L PG EY+V V +     ES     + +T +DSP  +    +T N  TV W
Sbjct: 669  EQSSTVLTGLRPGMEYMVHVWAQKGDQESKKADTKAQTDIDSPQNLVTDRVTENMATVSW 728

Query: 1379 IAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESP 1438
               RATI  Y +R+      G  RE  V   ++S  LT L PG EY V + A  G +ES 
Sbjct: 729  DPVRATIDRYVVRYTSAK-DGETREVPVGKEQSSTVLTGLRPGVEYTVHVWAQKGAQESK 787

Query: 1439 LLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPG 1498
                +  T  D P++L     T  +  +SWD    T+  Y + Y  T  N   +E  V  
Sbjct: 788  KADTKAQTDIDSPQNLVTDWVTENTATVSWDPVQATIDRYVVHY--TSANGETREVPVGK 845

Query: 1499 SKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSI 1558
             +S+  ++GL+PG++YT+ V+A  G  +    SK      +TEID P  +    V +N  
Sbjct: 846  EQSSTVLTGLRPGMEYTVHVWAQKGNQE----SKKADTKAQTEIDGPKNLVTDWVTENMA 901

Query: 1559 SVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPS 1618
            +V W P  + +  Y V  T  +  G T+    G + +   + GL+P +EY+V V+AQ  +
Sbjct: 902  TVSWDPVQATIDKYMVRYT--SADGETREVPVGKEHSSTVLTGLRPGMEYMVHVWAQKGA 959

Query: 1619 GESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFP 1678
             ES+     A T +D P+ L  + V      + W  P  Q+  Y +TY  P+  + E+  
Sbjct: 960  QESKKADTKAQTELDPPRNLRPSAVTQSGGILTWTPPSAQIHGYILTYQFPDGTVKEM-- 1017

Query: 1679 APDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTA---IPAPTDLKFTQVTP 1735
                E+    LQGL  G+ Y VS+VA      S+ +  T ST     P P+D    Q   
Sbjct: 1018 QLGREDQRFALQGLEQGATYPVSLVAFKGGRRSRNVSTTLSTVGARFPHPSDCSQVQQNS 1077

Query: 1736 TSLSAQWT 1743
             + S  +T
Sbjct: 1078 NAASGLYT 1085



 Score =  270 bits (689), Expect = 2e-71
 Identities = 197/637 (30%), Positives = 295/637 (46%), Gaps = 25/637 (3%)

Query: 1356 TGLD-----SPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSR 1410
            TGLD     +P G+     T +S  V W  P + +  Y + ++P       ++ +VP  +
Sbjct: 255  TGLDCAQVVTPQGLQLLKNTEDSLLVSW-EPSSQVDHYLLSYYPLGKELSGKQIQVPKEQ 313

Query: 1411 NSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDA 1470
            +S  +  L PGT+Y+V++  +     S       +T   V     V   T  SL + W+ 
Sbjct: 314  HSYEILGLLPGTKYIVTLRNVKNEVSSSPQHLLATTDLAVLGTAWVTDETENSLDVEWEN 373

Query: 1471 PAVTVRYYRITYGETGGNSPVQEFTVPGS---KSTATISGLKPGVDYTITVYAVTGRGDS 1527
            P+  V YY++ YG   G   V E TVP S   KS   I+GL PG +Y ITV  + G    
Sbjct: 374  PSTEVDYYKLRYGPMTGQE-VAEVTVPKSSDPKSRYDITGLHPGTEYKITVVPMRGE--- 429

Query: 1528 PASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKT 1587
                KPI +N RTEID P+ +    V +++ +V W P  + +  Y V  T  +  G TK 
Sbjct: 430  -LEGKPILLNGRTEIDSPTNVVTDRVTEDTATVSWDPVQAVIDKYVVRYT--SADGDTKE 486

Query: 1588 KTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDS 1647
                 D++   + GL+P   Y V V+A+  +  S+     A+T ID P  L    V  ++
Sbjct: 487  MAVHKDESSTVLTGLKPGEAYKVYVWAERGNQGSKKADTNALTEIDSPANLVTDRVTENT 546

Query: 1648 IKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAE-LQGLRPGSEYTVSVVALH 1706
              I+W+  Q  + +Y V Y+S +D   E      G+E ++  L GLRPG EYTV V A  
Sbjct: 547  ATISWDPVQATIDKYVVRYTSADD--QETREVLVGKEQSSTVLTGLRPGVEYTVHVWAQK 604

Query: 1707 DDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMK 1766
             D ES+       T I +P +L   +VT    +  W P    +  Y VR T     G  +
Sbjct: 605  GDRESKKADTNAPTDIDSPKNLVTDRVTENMATVSWDPVQAAIDKYVVRYT--SAGGETR 662

Query: 1767 EINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDAT 1826
            E+ +  + SS V++GL    +Y V V+A K    S+ A     T  ++  P+       T
Sbjct: 663  EVPVGKEQSSTVLTGLRPGMEYMVHVWAQKGDQESKKADTKAQT--DIDSPQNLVTDRVT 720

Query: 1827 ETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTL 1886
            E   T+SW     TI  + V    A      +  +  +  S  +TGL+PG +Y ++++  
Sbjct: 721  ENMATVSWDPVRATIDRYVVRYTSAKDGETREVPVGKEQSSTVLTGLRPGVEYTVHVWAQ 780

Query: 1887 NDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPRE 1946
                 S      A T ID+P NL     T N+  VSW P +A I  Y++ Y       RE
Sbjct: 781  KGAQESKKADTKAQTDIDSPQNLVTDWVTENTATVSWDPVQATIDRYVVHYTSANGETRE 840

Query: 1947 VVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSE 1983
            V        T   +TGL PG EYT++V A K NQ+S+
Sbjct: 841  VPVGKEQSST--VLTGLRPGMEYTVHVWAQKGNQESK 875



 Score =  240 bits (612), Expect = 1e-62
 Identities = 226/820 (27%), Positives = 353/820 (43%), Gaps = 53/820 (6%)

Query: 636  SHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRF 695
            S +  Y+L + P       K+  +P   +SY I GL PG                  T++
Sbjct: 286  SQVDHYLLSYYPLGKELSGKQIQVPKEQHSYEILGLLPG------------------TKY 327

Query: 696  DFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYE 755
              T  +    V+S+      T    ++ T+  VT+ T +S  V W + S  V  +++ Y 
Sbjct: 328  IVTLRNVKNEVSSSPQHLLATTDLAVLGTA-WVTDETENSLDVEWENPSTEVDYYKLRYG 386

Query: 756  LSEEGDEPQYLDLPSTA---TSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPD 812
                G E   + +P ++   +  +I  L PG +Y + V  +  + E   IL   +T   D
Sbjct: 387  -PMTGQEVAEVTVPKSSDPKSRYDITGLHPGTEYKITVVPMRGELEGKPILLNGRTEI-D 444

Query: 813  APPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQP 872
            +P +   D+V + +  V W   QA I  Y + Y+ S +G + E+ + +  +S  L+ L+P
Sbjct: 445  SPTNVVTDRVTEDTATVSWDPVQAVIDKYVVRYT-SADGDTKEMAVHKDESSTVLTGLKP 503

Query: 873  GVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPES 932
            G  Y + ++A   NQ S       +   T     + SP +L    VT+   TI W P ++
Sbjct: 504  GEAYKVYVWAERGNQGS-------KKADTNALTEIDSPANLVTDRVTENTATISWDPVQA 556

Query: 933  AVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQ 992
             +  Y V     +   E  + L     +   +TGL PGV Y   V+A    RESK     
Sbjct: 557  TIDKYVVRYTSAD-DQETREVLVGKEQSSTVLTGLRPGVEYTVHVWAQKGDRESKKADTN 615

Query: 993  QTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYP 1052
              T +D+P NL     T++   V W P +A I  Y +    +  G+ R+  VG   S   
Sbjct: 616  APTDIDSPKNLVTDRVTENMATVSWDPVQAAIDKYVVRY-TSAGGETREVPVGKEQSSTV 674

Query: 1053 LRNLQPASEYTVSLVAIKGNQESPKA-TGVFTTLQPGSSIPPYNTEVTETTIVITWTPAP 1111
            L  L+P  EY V + A KG+QES KA T   T +    ++      VTE    ++W P  
Sbjct: 675  LTGLRPGMEYMVHVWAQKGDQESKKADTKAQTDIDSPQNL--VTDRVTENMATVSWDPVR 732

Query: 1112 RIGFKLGVR--PSQGGEAPREVT--SDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIV 1167
                +  VR   ++ GE  REV    +  S V++GL PGVEY   +   +  QE      
Sbjct: 733  ATIDRYVVRYTSAKDGET-REVPVGKEQSSTVLTGLRPGVEYTVHVWAQKGAQE-SKKAD 790

Query: 1168 NKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHA 1227
             K  T +  P NL  +   +    TVSW+      I  Y +  T  NG+   + E  V  
Sbjct: 791  TKAQTDIDSPQNLVTDWVTE-NTATVSWD-PVQATIDRYVVHYTSANGE---TREVPVGK 845

Query: 1228 DQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTW 1287
            +QSS     L PG+EY V V+  K ++ES          +  P +L    +  +   V+W
Sbjct: 846  EQSSTVLTGLRPGMEYTVHVWAQKGNQESKKADTKAQTEIDGPKNLVTDWVTENMATVSW 905

Query: 1288 APPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHES 1347
              P    +  ++VRY+    E    E+ +    ++ VLT L PG EY+V V +     ES
Sbjct: 906  -DPVQATIDKYMVRYTSADGE--TREVPVGKEHSSTVLTGLRPGMEYMVHVWAQKGAQES 962

Query: 1348 TPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVP 1407
                 + +T LD P  +  S +T +   + W  P A I GY + +  +   G  +E ++ 
Sbjct: 963  KKADTKAQTELDPPRNLRPSAVTQSGGILTWTPPSAQIHGYILTY--QFPDGTVKEMQLG 1020

Query: 1408 HSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTV 1447
                   L  L  G  Y VS+VA  G   S  +    STV
Sbjct: 1021 REDQRFALQGLEQGATYPVSLVAFKGGRRSRNVSTTLSTV 1060



 Score =  223 bits (567), Expect = 2e-57
 Identities = 210/764 (27%), Positives = 332/764 (43%), Gaps = 55/764 (7%)

Query: 619  TPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNS---YTIKGLKPGV 675
            T    NS  ++W  P  + +  Y LR+ P        E T+P   +    Y I GL PG 
Sbjct: 360  TDETENSLDVEWENPS-TEVDYYKLRYGPMTGQ-EVAEVTVPKSSDPKSRYDITGLHPGT 417

Query: 676  VYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASS 735
             Y+  ++ ++  G  E             P+  N   G T   SP    ++ VTE TA+ 
Sbjct: 418  EYKITVVPMR--GELE-----------GKPILLN---GRTEIDSPTNVVTDRVTEDTAT- 460

Query: 736  FVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISE 795
              VSW      +  + V Y  S +GD  + + +    +S  +  L PG  Y   VY  +E
Sbjct: 461  --VSWDPVQAVIDKYVVRYT-SADGDTKE-MAVHKDESSTVLTGLKPGEAY--KVYVWAE 514

Query: 796  DGEQ-SLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSST 854
             G Q S    T+  T  D+P +   D+V + +  + W   QA I  Y + Y+ + +  + 
Sbjct: 515  RGNQGSKKADTNALTEIDSPANLVTDRVTENTATISWDPVQATIDKYVVRYTSADDQETR 574

Query: 855  ELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQ 914
            E+ + +  +S  L+ L+PGV+Y + ++A + ++ES     ++  T  P    + SP++L 
Sbjct: 575  EVLVGKEQSSTVLTGLRPGVEYTVHVWAQKGDRES-----KKADTNAPTD--IDSPKNLV 627

Query: 915  FVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEV-TGLSPGVTY 973
               VT+   T+ W P ++A+  Y   V+     G   + +P+ +   + V TGL PG+ Y
Sbjct: 628  TDRVTENMATVSWDPVQAAIDKY---VVRYTSAGGETREVPVGKEQSSTVLTGLRPGMEY 684

Query: 974  YFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGL 1033
               V+A    +ESK    +  T +D+P NL     T++   V W P RA I  Y +    
Sbjct: 685  MVHVWAQKGDQESKKADTKAQTDIDSPQNLVTDRVTENMATVSWDPVRATIDRYVVRYTS 744

Query: 1034 TRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKA-TGVFTTLQPGSSIP 1092
             + G+ R+  VG   S   L  L+P  EYTV + A KG QES KA T   T +    ++ 
Sbjct: 745  AKDGETREVPVGKEQSSTVLTGLRPGVEYTVHVWAQKGAQESKKADTKAQTDIDSPQNL- 803

Query: 1093 PYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVT--SDSGSIVVSGLTPGVEYV 1150
                 VTE T  ++W P      +  V  +      REV    +  S V++GL PG+EY 
Sbjct: 804  -VTDWVTENTATVSWDPVQATIDRYVVHYTSANGETREVPVGKEQSSTVLTGLRPGMEYT 862

Query: 1151 YTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITT 1210
              +   +  QE       K  T +  P NL  +   +  + TVSW+      I  Y +  
Sbjct: 863  VHVWAQKGNQE-SKKADTKAQTEIDGPKNLVTDWVTE-NMATVSWD-PVQATIDKYMVRY 919

Query: 1211 TPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPP 1270
            T  +G+   + E  V  + SS     L PG+EY V V+  K  +ES          + PP
Sbjct: 920  TSADGE---TREVPVGKEHSSTVLTGLRPGMEYMVHVWAQKGAQESKKADTKAQTELDPP 976

Query: 1271 TDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLP 1330
             +LR + +      +TW  PPS  +  +++ Y     +  V E+ +   D    L  L  
Sbjct: 977  RNLRPSAVTQSGGILTWT-PPSAQIHGYILTYQ--FPDGTVKEMQLGREDQRFALQGLEQ 1033

Query: 1331 GTEYVVSVSSVYEQHESTPLRGRQKT-GLDSPTGIDFSDITANS 1373
            G  Y VS+ +      S  +     T G   P   D S +  NS
Sbjct: 1034 GATYPVSLVAFKGGRRSRNVSTTLSTVGARFPHPSDCSQVQQNS 1077



 Score =  192 bits (487), Expect = 4e-48
 Identities = 168/669 (25%), Positives = 281/669 (42%), Gaps = 60/669 (8%)

Query: 1541 EIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIE 1600
            ++  P  +Q+    ++S+ V W PSS  V  Y ++  P       K      +Q    I 
Sbjct: 261  QVVTPQGLQLLKNTEDSLLVSWEPSSQ-VDHYLLSYYPLGKELSGKQIQVPKEQHSYEIL 319

Query: 1601 GLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVS 1660
            GL P  +Y+V++        S P    A T++        TD   +S+ + WE+P  +V 
Sbjct: 320  GLLPGTKYIVTLRNVKNEVSSSPQHLLATTDLAVLGTAWVTDETENSLDVEWENPSTEVD 379

Query: 1661 RYRVTYS--SPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQ 1718
             Y++ Y   + ++      P     +   ++ GL PG+EY ++VV +  ++E +P++   
Sbjct: 380  YYKLRYGPMTGQEVAEVTVPKSSDPKSRYDITGLHPGTEYKITVVPMRGELEGKPILLNG 439

Query: 1719 STAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVV 1778
             T I +PT++   +VT  + +  W P    +  Y VR T  +  G  KE+ +  D SS V
Sbjct: 440  RTEIDSPTNVVTDRVTEDTATVSWDPVQAVIDKYVVRYTSAD--GDTKEMAVHKDESSTV 497

Query: 1779 VSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKT 1838
            ++GL     Y+V V+A +    S+ A      L  +  P        TE T TISW    
Sbjct: 498  LTGLKPGEAYKVYVWAERGNQGSKKAD--TNALTEIDSPANLVTDRVTENTATISWDPVQ 555

Query: 1839 ETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVID 1898
             TI  + V    A+ Q   +  +  +  S  +TGL+PG +Y ++++    +  S     +
Sbjct: 556  ATIDKYVVRYTSADDQETREVLVGKEQSSTVLTGLRPGVEYTVHVWAQKGDRESKKADTN 615

Query: 1899 ASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEA 1958
            A T ID+P NL     T N   VSW P +A I  Y+++Y   G   REV        T  
Sbjct: 616  APTDIDSPKNLVTDRVTENMATVSWDPVQAAIDKYVVRYTSAGGETREVPVGKEQSST-- 673

Query: 1959 TITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQKTP---------------------- 1996
             +TGL PG EY ++V A K +Q+S+    + +T   +P                      
Sbjct: 674  VLTGLRPGMEYMVHVWAQKGDQESKKADTKAQTDIDSPQNLVTDRVTENMATVSWDPVRA 733

Query: 1997 -----FVTHPGYDTGNGIQLP--------GTSGQQPSVGQQM-IFEEHGFRRTTPPTTAT 2042
                  V +     G   ++P          +G +P V   + ++ + G + +    T  
Sbjct: 734  TIDRYVVRYTSAKDGETREVPVGKEQSSTVLTGLRPGVEYTVHVWAQKGAQESKKADTKA 793

Query: 2043 PIRHRPRPYPPNVGQEALSQ--TTISWAPFQDT-SEYIISCHPVGTDEEPLQFRVPGTST 2099
                     P N+  + +++   T+SW P Q T   Y++  H    + E  +  V    +
Sbjct: 794  ---QTDIDSPQNLVTDWVTENTATVSWDPVQATIDRYVV--HYTSANGETREVPVGKEQS 848

Query: 2100 SATLTGLTRGATYNIIVEALKDQQRH-----KVREEVVTVGNSVNEGLNQPTDDSCFDPY 2154
            S  LTGL  G  Y + V A K  Q       K + E+    N V + + +      +DP 
Sbjct: 849  STVLTGLRPGMEYTVHVWAQKGNQESKKADTKAQTEIDGPKNLVTDWVTENMATVSWDPV 908

Query: 2155 --TVSHYAV 2161
              T+  Y V
Sbjct: 909  QATIDKYMV 917



 Score = 37.0 bits (84), Expect = 0.23
 Identities = 34/127 (26%), Positives = 54/127 (42%), Gaps = 14/127 (11%)

Query: 2052 PPNVGQEALSQTT--ISWAPFQDTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRG 2109
            P N+  + +++ T  ISW P Q T +  +  +    D+E  +  V    +S  LTGL  G
Sbjct: 534  PANLVTDRVTENTATISWDPVQATIDKYVVRYTSADDQETREVLVGKEQSSTVLTGLRPG 593

Query: 2110 ATYNIIVEALK-DQQRHKVREEVVT--------VGNSVNEGLNQPTDD---SCFDPYTVS 2157
              Y + V A K D++  K      T        V + V E +   + D   +  D Y V 
Sbjct: 594  VEYTVHVWAQKGDRESKKADTNAPTDIDSPKNLVTDRVTENMATVSWDPVQAAIDKYVVR 653

Query: 2158 HYAVGDE 2164
            + + G E
Sbjct: 654  YTSAGGE 660


>gi|188528648 tenascin XB isoform 1 precursor [Homo sapiens]
          Length = 4242

 Score =  313 bits (801), Expect = 2e-84
 Identities = 345/1553 (22%), Positives = 607/1553 (39%), Gaps = 191/1553 (12%)

Query: 616  ITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGV 675
            +T T S P+S  + W  PQ      + ++++ ++  GR +   + G  +  T++GL+PG 
Sbjct: 2528 LTVTGSSPDSLSLSWTVPQ-GRFDSFTVQYKDRD--GRPQAVRVGGQESKVTVRGLEPGR 2584

Query: 676  VYEGQLISIQQYGHQ--EVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITA 733
             Y+  L  + + G +   V+    T     T     T+T E  P  P +    ++T+ T 
Sbjct: 2585 KYKMHLYGLHE-GRRLGPVSAVGVTEDEAETTQAVPTMTPEP-PIKPRLGEL-TMTDATP 2641

Query: 734  SSFVVSWVSASDTVSGFRVEYELSEEGD-EPQYLDLPSTATSVNIPDLLPGRKYIVNVYQ 792
             S  +SW         F V+Y     GD +P+ + +P     V I  L P  KY +N+Y 
Sbjct: 2642 DSLSLSWTVPEGQFDHFLVQYR---NGDGQPKAVRVPGHEDGVTISGLEPDHKYKMNLYG 2698

Query: 793  I---SEDGEQSLILSTS-----------QTTAPDAPPDPTVDQVDDT-----SIVVRWSR 833
                   G  S+I  T+            T AP+ P +P + ++  T     S+ + W+ 
Sbjct: 2699 FHGGQRVGPISVIGVTAAEEETPSPTELSTEAPEPPEEPLLGELTVTGSSPDSLSLSWTI 2758

Query: 834  PQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPV- 892
            PQ     + + Y    +G    + +    + VT+  L+PG +Y + +Y + E +   PV 
Sbjct: 2759 PQGHFDSFTVQYKDR-DGRPQVMRVRGEESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVS 2817

Query: 893  ----------VIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVI 942
                        Q   T TP     P   +L   + T   +++ W  PE      + D  
Sbjct: 2818 TVGVTEDEAETTQAVPTTTPEPPNKPRLGELTVTDATPDSLSLSWMVPEG-----QFDHF 2872

Query: 943  PVNLPGEHGQ----RLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLD 998
             V      GQ    R+P        ++GL P   Y   ++    G+   P++    T  +
Sbjct: 2873 LVQYRNGDGQPKVVRVP-GHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPISVIGVTAAE 2931

Query: 999  ----APTN----------------LQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQ 1038
                APT                 L     +  ++ + WT P+ +   + +     R G+
Sbjct: 2932 EETPAPTEPSTEAPEPPEEPLLGELTVTGSSPDSLSLSWTIPQGRFDSFTVQYK-DRDGR 2990

Query: 1039 PRQYNVGPSVSKYPLRNLQPASEYT--------------VSLVAIKGNQESPKATGVFTT 1084
            P+   V    S+  +  L+P  +Y               VS V +   ++  + T    T
Sbjct: 2991 PQVVRVRGEESEVTVGGLEPGCKYKMHLYGLHEGQRVGPVSAVGVTAPKDEAETTQAVPT 3050

Query: 1085 LQPGSSIPPYNTEVTET-----TIVITW-TPAPRIG-FKLGVRPSQGGEAPREVTSDSGS 1137
            + P   I P   E+T T     ++ ++W  P  +   F +  R   G      V      
Sbjct: 3051 MTPEPPIKPRLGELTVTDATPDSLSLSWMVPEGQFDHFLVQYRNGDGQPKAVRVPGHEDG 3110

Query: 1138 IVVSGLTPGVEYVYTIQVLRDGQERDAPI----VNKVVTPLSPPTNLHLEA-----NPDT 1188
            + +SGL P  +Y   +     GQ R  P+    V +  TP   PT    EA      P  
Sbjct: 3111 VTISGLEPDHKYKMNLYGFHGGQ-RVGPVSAIGVTEEETP--SPTEPSTEAPEAPEEPLL 3167

Query: 1189 GVLTVSWERSTTPDITGYRIT---------TTPTNGQQGNSLEEVVHADQSSCTFDNLSP 1239
            G LTV+    ++PD      T         T     + G      V  ++S  T   L P
Sbjct: 3168 GELTVT---GSSPDSLSLSWTVPQGRFDSFTVQYKDRDGQPQVVRVRGEESEVTVGGLEP 3224

Query: 1240 GLEYNVSVYTVKDDKESVPISD--------TIIPAVPPPTDLRFTNIGPDTMRVTWAPPP 1291
            G +Y + +Y + + +   P+S         T +P  P   +L    +  D++ ++W    
Sbjct: 3225 GRKYKMHLYGLHEGQRVGPVSTVGITAPLPTPLPVEPRLGELAVAAVTSDSVGLSWTVAQ 3284

Query: 1292 SIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLR 1351
                 +FLV+Y   + +     + +S    AV ++ L P  +Y   +  +       P+ 
Sbjct: 3285 G-PFDSFLVQYRDAQGQPQA--VPVSGDLRAVAVSGLDPARKYKFLLFGLQNGKRHGPVP 3341

Query: 1352 GRQKTGLDSPTG-----IDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRV 1406
               +T  D+        +  +D T +S  + W  P      + +++  +   GR +   V
Sbjct: 3342 VEARTAPDTKPSPRLGELTVTDATPDSVGLSWTVPEGEFDSFVVQYKDK--DGRLQVVPV 3399

Query: 1407 PHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTV---SDVPR---DLEVVAAT 1460
              ++  +T+  L P  +Y   +  L+GR+    +    +T     ++P    +L V   T
Sbjct: 3400 AANQREVTVQGLEPSRKYRFLLYGLSGRKRLGPISADSTTAPLEKELPPHLGELTVAEET 3459

Query: 1461 PTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYA 1520
             +SL +SW         + + Y +T G    +   V   + T T+  L+PG  Y   +Y 
Sbjct: 3460 SSSLRLSWTVAQGPFDSFVVQYRDTDGQP--RAVPVAADQRTVTVEDLEPGKKYKFLLYG 3517

Query: 1521 VTG---------------RGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPS 1565
            + G                 D+PA           E  +   + VTD   +S+ + W  +
Sbjct: 3518 LLGGKRLGPVSALGMTAPEEDTPAPELAPEAPEPPEEPRLGVLTVTDTTPDSMRLSWSVA 3577

Query: 1566 SSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLV 1625
              P   + V     NG  P      G DQ+++ I GL+P+  Y   +Y  +      PL 
Sbjct: 3578 QGPFDSFVVQYEDTNGQ-PQALLVDG-DQSKILISGLEPSTPYRFLLYGLHEGKRLGPLS 3635

Query: 1626 QTAVTNI---------DRPK--GLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIH 1674
                T +          RP+   L+ TDV   S+++ WE+P G    + + +  P     
Sbjct: 3636 AEGTTGLAPAGQTSEESRPRLSQLSVTDVTTSSLRLNWEAPPGAFDSFLLRFGVPSPSTL 3695

Query: 1675 ELFPAP--------DGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIP--- 1723
            E  P P         G   +A L+ LR G+ Y++++  L    ++  + GT  T  P   
Sbjct: 3696 EPHPRPLLQRELMVPGTRHSAVLRDLRSGTLYSLTLYGLRGPHKADSIQGTARTLSPVLE 3755

Query: 1724 APTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLM 1783
            +P DL+F+++  TS    W PP  +   ++V     +   P + + +   + +  + GL+
Sbjct: 3756 SPRDLQFSEIRETSAKVNWMPPPSRADSFKVSYQLADGGEP-QSVQVDGQARTQKLQGLI 3814

Query: 1784 VATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITG 1843
               +YEV+V +++    S P  G +TT+ +   P + R  + TE    + W+     +  
Sbjct: 3815 PGARYEVTVVSVRGFEESEPLTGFLTTVPD--GPTQLRALNLTEGFAVLHWKPPQNPVDT 3872

Query: 1844 FQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAI 1903
            + V  V A G  P+Q         Y +  L   T+Y   +  L     +SP  I  +T +
Sbjct: 3873 YDVQ-VTAPGAPPLQAETPGSAVDYPLHDLVLHTNYTATVRGLRGPNLTSPASITFTTGL 3931

Query: 1904 DAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGL 1963
            +AP +L     TP + L++W  P  R  GY++ +  PG   +E++     G+T   + GL
Sbjct: 3932 EAPRDLEAKEVTPRTALLTWTEPPVRPAGYLLSFHTPGGQNQEIL--LPGGITSHQLLGL 3989

Query: 1964 EPGTEYTIYVIALKNNQKSEPLIGRKKT-VQKTPFVTHPGYDTGNGIQLPGTS 2015
             P T Y   + A+       P+     T   + PF    G +  NG     TS
Sbjct: 3990 FPSTSYNARLQAMWGQSLLPPVSTSFTTGGLRIPFPRDCGEEMQNGAGASRTS 4042



 Score =  287 bits (735), Expect = 7e-77
 Identities = 378/1726 (21%), Positives = 647/1726 (37%), Gaps = 291/1726 (16%)

Query: 616  ITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGV 675
            +T T   P+S  + W   Q      +++++  K++ G+ +   + G  N  T+ GL P  
Sbjct: 1267 LTVTGVTPDSLRLSWTVAQ-GPFDSFMVQY--KDAQGQPQAVPVAGDENEVTVPGLDPDR 1323

Query: 676  VYEGQLISI---QQYGHQEV---TRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVT 729
             Y+  L  +   Q+ G + V   T        T +P    T   E+ P  PL+    +VT
Sbjct: 1324 KYKMNLYGLRGRQRVGPESVVAKTAPQEDVDETPSPTELGTEAPES-PEEPLLGEL-TVT 1381

Query: 730  EITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVN 789
              +  S  + W     +   F V+Y+  +    P+ + +    + V +  L PG KY ++
Sbjct: 1382 GSSPDSLSLFWTVPQGSFDSFTVQYK--DRDGRPRAVRVGGKESEVTVGGLEPGHKYKMH 1439

Query: 790  VYQISEDGEQSLILSTSQTTAP---------DAPPDP-----TVDQVDDTSIVVRWSRPQ 835
            +Y + E G++   +S    TAP         ++P +P     TV  V   S+ + W+ P+
Sbjct: 1440 LYGLHE-GQRVGPVSAVGVTAPQQEETPPATESPLEPRLGELTVTDVTPNSVGLSWTVPE 1498

Query: 836  APITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQ 895
                 + + Y    +G    + +      VT+ +L+P  +Y + +Y + + Q   P+ + 
Sbjct: 1499 GQFDSFIVQYKDK-DGQPQVVPVAADQREVTVYNLEPERKYKMNMYGLHDGQRMGPLSVV 1557

Query: 896  QETTGTPRSDTVPSPR--------DLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLP 947
              T   P +    + +        +L   ++T   V + WT PE     +   V+     
Sbjct: 1558 IVTAPLPPAPATEASKPPLEPRLGELTVTDITPDSVGLSWTVPEGEFDSF---VVQYKDR 1614

Query: 948  GEHGQRLPISRNTFAEVT--GLSPGVTYYFKVFAVSHGRESKPLTAQQTTKL------DA 999
                Q +P++ +   EVT   L P   Y F +F +  G+   P++ +  T         A
Sbjct: 1615 DGQPQVVPVAADQ-REVTIPDLEPSRKYKFLLFGIQDGKRRSPVSVEAKTVARGDASPGA 1673

Query: 1000 PTNLQFVNETDST---VLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNL 1056
            P  L  +  TD T   + + WT P  Q   +   V    +  P+   V        +  L
Sbjct: 1674 PPRLGELWVTDPTPDSLRLSWTVPEGQFDSF--VVQFKDKDGPQVVPVEGHERSVTVTPL 1731

Query: 1057 QPASEYTVSLVAIKGNQESPKATGVFTTL------QPGSSIPPYN--------TEVTETT 1102
                +Y   L  + G +     T   TT         G+  PP          T VT+ +
Sbjct: 1732 DAGRKYRFLLYGLLGKKRHGPLTADGTTEARSAMDDTGTKRPPKPRLGEELQVTTVTQNS 1791

Query: 1103 IVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGS---IVVSGLTPGVEYVYTIQVLRDG 1159
            + ++WT  P   F   V   +  +   +V    GS   + V GL P   Y   +  L  G
Sbjct: 1792 VGLSWT-VPEGQFDSFVVQYKDRDGQPQVVPVEGSLREVSVPGLDPAHRYKLLLYGLHHG 1850

Query: 1160 QERDAPIVNKVVTPLSPPTNLHLEA------NPDTGVLTVSWERS---------TTPDIT 1204
            + R  PI    +T     T     A       P  G LTV    S         T  +  
Sbjct: 1851 K-RVGPISAVAITAGREETETETTAPTPPAPEPHLGELTVEEATSHTLHLSWMVTEGEFD 1909

Query: 1205 GYRITTTPTNGQQGNSLEEV-VHADQSSCTFDNLSPGLEYNVSVYTVKDDK-------ES 1256
             + I  T  +GQ    L+ V +  D++  T   L     Y V++Y   D K       E+
Sbjct: 1910 SFEIQYTDRDGQ----LQMVRIGGDRNDITLSGLESDHRYLVTLYGFSDGKHVGPVHVEA 1965

Query: 1257 VPISDTIIPAVPPPT-----------DLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPV 1305
            + + +   P+ PP             +L  T+  PD++ ++W  P      +FLV+Y   
Sbjct: 1966 LTVPEEEKPSEPPTATPEPPIKPRLGELTVTDATPDSLSLSWTVPEG-QFDHFLVQYR-- 2022

Query: 1306 KNEEDVAELSISPSDNAVVLTNLLPGTEYV--------------VSVSSVYEQHESTPLR 1351
              +     + +   +  V ++ L P  +Y               VSV  V    E TP  
Sbjct: 2023 NGDGQPKAVRVPGHEEGVTISGLEPDHKYKMNLYGFHGGQRMGPVSVVGVTAAEEETPSP 2082

Query: 1352 GRQKTGLDSPTG------IDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDR 1405
                     P        +  +  + +S ++ W  P+     + +++      GRP+  R
Sbjct: 2083 TEPSMEAPEPAEEPLLGELTVTGSSPDSLSLSWTVPQGRFDSFTVQYKDR--DGRPQVVR 2140

Query: 1406 VPHSRNSITLTNLTPGTEYVVSIVALN-GREESPL----LIGQQSTVSDVPR------DL 1454
            V    + +T+  L PG +Y + +  L+ GR   P+    +   +    D P        +
Sbjct: 2141 VGGEESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVSAVGVTAPEEESPDAPLAKLRLGQM 2200

Query: 1455 EVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDY 1514
             V   T  SL +SW  P     ++ + +    G+   +   VPG +   TISGL+P   Y
Sbjct: 2201 TVRDITSDSLSLSWTVPEGQFDHFLVQF--KNGDGQPKAVRVPGHEDGVTISGLEPDHKY 2258

Query: 1515 TITVYAVTG-RGDSPASSKPISINYRTEIDKPS----------------QMQVTDVQDNS 1557
             + +Y   G +   P S+  ++   + E   P+                ++ VTD   +S
Sbjct: 2259 KMNLYGFHGGQRVGPVSAVGLTAPGKDEEMAPASTEPPTPEPPIKPRLEELTVTDATPDS 2318

Query: 1558 ISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNP 1617
            +S+ W         + V    KNG G  K       +  +TI GL+P  +Y +++Y  + 
Sbjct: 2319 LSLSWTVPEGQFDHFLVQY--KNGDGQPKATRVPGHEDRVTISGLEPDNKYKMNLYGFHG 2376

Query: 1618 SGESQPLVQTAVT------------NIDRPK--------GLAFTDVDVDSIKIAWESPQG 1657
                 P+    VT            +++ P+         L  T    DS+ ++W  PQG
Sbjct: 2377 GQRVGPVSAIGVTAAEEETPSPTEPSMEAPEPPEEPLLGELTVTGSSPDSLSLSWTVPQG 2436

Query: 1658 QVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEY-----------------TV 1700
            +   + V Y    DG  ++     GEE    + GL PG +Y                 TV
Sbjct: 2437 RFDSFTVQYKD-RDGRPQVVRV-GGEESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVSTV 2494

Query: 1701 SVVALHDDMESQPLIGTQSTAIPAPT------DLKFTQVTPTSLSAQWTPPNVQLTGYRV 1754
             V A  +D++  P      T  P P       +L  T  +P SLS  WT P  +   + V
Sbjct: 2495 GVTAPQEDVDETPSPTEPGTEAPGPPEEPLLGELTVTGSSPDSLSLSWTVPQGRFDSFTV 2554

Query: 1755 RVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENV 1814
            +   K++ G  + + +    S V V GL    KY++ +Y L +     P   V  T +  
Sbjct: 2555 QY--KDRDGRPQAVRVGGQESKVTVRGLEPGRKYKMHLYGLHEGRRLGPVSAVGVTEDEA 2612

Query: 1815 -----------SPPRRAR-----VTDATETTITISWRTKTETITGFQVDAVPANGQTPIQ 1858
                        PP + R     +TDAT  ++++SW         F V     +GQ    
Sbjct: 2613 ETTQAVPTMTPEPPIKPRLGELTMTDATPDSLSLSWTVPEGQFDHFLVQYRNGDGQPKAV 2672

Query: 1859 RTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTA------------IDAP 1906
            R +       TI+GL+P   YK+ LY  +   R  P+ +   TA             +AP
Sbjct: 2673 R-VPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPISVIGVTAAEEETPSPTELSTEAP 2731

Query: 1907 --------SNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEA 1958
                      L    ++P+SL +SW  P+     + ++Y+     P+  V R R   +E 
Sbjct: 2732 EPPEEPLLGELTVTGSSPDSLSLSWTIPQGHFDSFTVQYKDRDGRPQ--VMRVRGEESEV 2789

Query: 1959 TITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQKTPFVTHPGYDTGNGIQLPGTSGQQ 2018
            T+ GLEPG +Y +++  L   ++  P+         T  VT    +T   +         
Sbjct: 2790 TVGGLEPGRKYKMHLYGLHEGRRVGPV--------STVGVTEDEAETTQAV--------- 2832

Query: 2019 PSVGQQMIFEEHGFRRTTPPTTATPIRHRPRPYPPNVGQEALSQTTISWAPFQDTSEYII 2078
                               PTT     ++PR     V        ++SW   +   ++ +
Sbjct: 2833 -------------------PTTTPEPPNKPRLGELTVTDATPDSLSLSWMVPEGQFDHFL 2873

Query: 2079 SCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQR 2124
              +  G D +P   RVPG     T++GL     Y + +      QR
Sbjct: 2874 VQYRNG-DGQPKVVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQR 2918



 Score =  277 bits (708), Expect = 1e-73
 Identities = 328/1543 (21%), Positives = 584/1543 (37%), Gaps = 211/1543 (13%)

Query: 616  ITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGV 675
            +T T S P+S  + W  PQ      + ++++ ++  GR +   + G  +  T+ GL+PG 
Sbjct: 2417 LTVTGSSPDSLSLSWTVPQ-GRFDSFTVQYKDRD--GRPQVVRVGGEESEVTVGGLEPGR 2473

Query: 676  VYEGQLISIQQYGHQEVTRFD-FTTTSTSTPVTSNTVTGETT---------PFSPLVATS 725
             Y+  L     YG  E  R    +T   + P      T   T         P  PL+   
Sbjct: 2474 KYKMHL-----YGLHEGRRVGPVSTVGVTAPQEDVDETPSPTEPGTEAPGPPEEPLLGEL 2528

Query: 726  ESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRK 785
             +VT  +  S  +SW         F V+Y+  +    PQ + +    + V +  L PGRK
Sbjct: 2529 -TVTGSSPDSLSLSWTVPQGRFDSFTVQYK--DRDGRPQAVRVGGQESKVTVRGLEPGRK 2585

Query: 786  YIVNVYQISED---GEQSLILSTSQ---------TTAPDAPPDPTVDQVDDT-----SIV 828
            Y +++Y + E    G  S +  T           T  P+ P  P + ++  T     S+ 
Sbjct: 2586 YKMHLYGLHEGRRLGPVSAVGVTEDEAETTQAVPTMTPEPPIKPRLGELTMTDATPDSLS 2645

Query: 829  VRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQE 888
            + W+ P+     + + Y    +G    + +P   + VT+S L+P  +Y + +Y     Q 
Sbjct: 2646 LSWTVPEGQFDHFLVQYRNG-DGQPKAVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQR 2704

Query: 889  STPVVI-----QQETTGTPRSDTVPSPRDLQFVEVTDVKVT--------IMWTPPESAVT 935
              P+ +      +E T +P   +  +P   +   + ++ VT        + WT P+    
Sbjct: 2705 VGPISVIGVTAAEEETPSPTELSTEAPEPPEEPLLGELTVTGSSPDSLSLSWTIPQG--- 2761

Query: 936  GYRVDVIPVNLPGEHGQ-RLPISRNTFAEVT--GLSPGVTYYFKVFAVSHGRESKPLTAQ 992
                D   V      G+ ++   R   +EVT  GL PG  Y   ++ +  GR   P++  
Sbjct: 2762 --HFDSFTVQYKDRDGRPQVMRVRGEESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVSTV 2819

Query: 993  QTTKLDAPTN------------------LQFVNETDSTVLVRWTPPRAQITGYRLTVGLT 1034
              T+ +A T                   L   + T  ++ + W  P  Q   + L     
Sbjct: 2820 GVTEDEAETTQAVPTTTPEPPNKPRLGELTVTDATPDSLSLSWMVPEGQFDHF-LVQYRN 2878

Query: 1035 RRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTL--------- 1085
              GQP+   V        +  L+P  +Y ++L    G Q     + +  T          
Sbjct: 2879 GDGQPKVVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPISVIGVTAAEEETPAPT 2938

Query: 1086 QPGSSIP-----PYNTEVTET-----TIVITWT-PAPRI-GFKLGVRPSQGGEAPREVTS 1133
            +P +  P     P   E+T T     ++ ++WT P  R   F +  +   G      V  
Sbjct: 2939 EPSTEAPEPPEEPLLGELTVTGSSPDSLSLSWTIPQGRFDSFTVQYKDRDGRPQVVRVRG 2998

Query: 1134 DSGSIVVSGLTPGVEYVYTIQVLRDGQERD--------APIVNKVVTPLSPPTNLHLEAN 1185
            +   + V GL PG +Y   +  L +GQ           AP      T   P         
Sbjct: 2999 EESEVTVGGLEPGCKYKMHLYGLHEGQRVGPVSAVGVTAPKDEAETTQAVPTMTPEPPIK 3058

Query: 1186 PDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHAD-----------QSSCTF 1234
            P  G LTV+     TPD     ++     GQ  + L +  + D           +   T 
Sbjct: 3059 PRLGELTVT---DATPD--SLSLSWMVPEGQFDHFLVQYRNGDGQPKAVRVPGHEDGVTI 3113

Query: 1235 DNLSPGLEYNVSVYTVKDDKESVPISDTIIPA--VPPPTD----------------LRFT 1276
              L P  +Y +++Y     +   P+S   +     P PT+                L  T
Sbjct: 3114 SGLEPDHKYKMNLYGFHGGQRVGPVSAIGVTEEETPSPTEPSTEAPEAPEEPLLGELTVT 3173

Query: 1277 NIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVV 1336
               PD++ ++W  P      +F V+Y     +  V    +   ++ V +  L PG +Y +
Sbjct: 3174 GSSPDSLSLSWTVPQG-RFDSFTVQYKDRDGQPQVVR--VRGEESEVTVGGLEPGRKYKM 3230

Query: 1337 SVSSVYEQHESTPLRGRQKTG-LDSPTGID-------FSDITANSFTVHWIAPRATITGY 1388
             +  ++E     P+     T  L +P  ++        + +T++S  + W   +     +
Sbjct: 3231 HLYGLHEGQRVGPVSTVGITAPLPTPLPVEPRLGELAVAAVTSDSVGLSWTVAQGPFDSF 3290

Query: 1389 RIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVAL-NGREESPLLIGQQSTV 1447
             +++      G+P+   V     ++ ++ L P  +Y   +  L NG+   P+ +  ++  
Sbjct: 3291 LVQYRDAQ--GQPQAVPVSGDLRAVAVSGLDPARKYKFLLFGLQNGKRHGPVPVEARTAP 3348

Query: 1448 SDVPR----DLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTA 1503
               P     +L V  ATP S+ +SW  P      + + Y +  G   +Q   V  ++   
Sbjct: 3349 DTKPSPRLGELTVTDATPDSVGLSWTVPEGEFDSFVVQYKDKDGR--LQVVPVAANQREV 3406

Query: 1504 TISGLKPGVDYTITVYAVTGRGD-SPASSKPISINYRTEIDKP-SQMQVTDVQDNSISVK 1561
            T+ GL+P   Y   +Y ++GR    P S+   +     E+     ++ V +   +S+ + 
Sbjct: 3407 TVQGLEPSRKYRFLLYGLSGRKRLGPISADSTTAPLEKELPPHLGELTVAEETSSSLRLS 3466

Query: 1562 WLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYV------------ 1609
            W  +  P   + V    ++  G  +      DQ  +T+E L+P  +Y             
Sbjct: 3467 WTVAQGPFDSFVVQY--RDTDGQPRAVPVAADQRTVTVEDLEPGKKYKFLLYGLLGGKRL 3524

Query: 1610 --VSVYAQNPSGESQPLVQTAVTNIDRPKG-----LAFTDVDVDSIKIAWESPQGQVSRY 1662
              VS        E  P  + A    + P+      L  TD   DS++++W   QG    +
Sbjct: 3525 GPVSALGMTAPEEDTPAPELAPEAPEPPEEPRLGVLTVTDTTPDSMRLSWSVAQGPFDSF 3584

Query: 1663 RVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAI 1722
             V Y         L    DG++    + GL P + Y   +  LH+     PL    +T +
Sbjct: 3585 VVQYEDTNGQPQALLV--DGDQSKILISGLEPSTPYRFLLYGLHEGKRLGPLSAEGTTGL 3642

Query: 1723 -----------PAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVR--------VTPKEKTG 1763
                       P  + L  T VT +SL   W  P      + +R        + P  +  
Sbjct: 3643 APAGQTSEESRPRLSQLSVTDVTTSSLRLNWEAPPGAFDSFLLRFGVPSPSTLEPHPRPL 3702

Query: 1764 PMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENV-SPPRRARV 1822
              +E+ +     S V+  L   T Y +++Y L+    +   QG   TL  V   PR  + 
Sbjct: 3703 LQRELMVPGTRHSAVLRDLRSGTLYSLTLYGLRGPHKADSIQGTARTLSPVLESPRDLQF 3762

Query: 1823 TDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIY 1882
            ++  ET+  ++W         F+V    A+G  P    +    R+  + GL PG  Y++ 
Sbjct: 3763 SEIRETSAKVNWMPPPSRADSFKVSYQLADGGEPQSVQVDGQARTQKLQGLIPGARYEVT 3822

Query: 1883 LYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGS 1942
            + ++     S P+    +T  D P+ LR L  T    ++ W+PP+  +  Y ++   PG+
Sbjct: 3823 VVSVRGFEESEPLTGFLTTVPDGPTQLRALNLTEGFAVLHWKPPQNPVDTYDVQVTAPGA 3882

Query: 1943 PPREVVPRPRPG-VTEATITGLEPGTEYTIYVIALKNNQKSEP 1984
            PP +      PG   +  +  L   T YT  V  L+    + P
Sbjct: 3883 PPLQA---ETPGSAVDYPLHDLVLHTNYTATVRGLRGPNLTSP 3922



 Score =  254 bits (650), Expect = 5e-67
 Identities = 370/1703 (21%), Positives = 624/1703 (36%), Gaps = 298/1703 (17%)

Query: 629  QWNAPQPSHISKYILRWRPKNSVGRWK-EATIPGHLNSYTIKGLKPGVVYEGQLISIQQY 687
            +W  P P  +  Y +++ P          A +P   ++Y  +GL PG  Y+         
Sbjct: 768  EWT-PAPGPVDAYEIQFIPTTEGASPPFTARVPSSASAYDQRGLAPGQEYQ--------- 817

Query: 688  GHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTV 747
                VT      TS   P +    T    P          V  +T ++  + W+     V
Sbjct: 818  ----VTVRALRGTSWGLPASKTITTMIDGP------QDLRVVAVTPTTLELGWLRPQAEV 867

Query: 748  SGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNV---------YQIS---E 795
              F V Y  +  G++   L++P  A    + DL+PG +Y+V V         Y  S    
Sbjct: 868  DRFVVSYVSA--GNQRVRLEVPPEADGTLLTDLMPGVEYVVTVTAERGRAVSYPASVRAN 925

Query: 796  DGEQSL-ILSTSQTTAPDAPPDPTVDQV------------------DDTS-IVVRWSRPQ 835
             G   L +L T+    P  P      Q                   D+T  + V W+   
Sbjct: 926  TGSSPLGLLGTTDEPPPSGPSTTQGAQAPLLQQRPQELGELRVLGRDETGRLRVVWTAQP 985

Query: 836  APITGYRI-VYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEEN-QESTPVV 893
                 +++ +  P   G+  E+ LP       +    PG  Y ++++ V    + S P++
Sbjct: 986  DTFAYFQLRMRVPEGPGAHEEV-LPGDVRQALVPPPPPGTPYELSLHGVPPGGKPSDPII 1044

Query: 894  IQ------QETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRV-----DVI 942
             Q      +E  G  +S   P   +L   + T   + + WT PE     + +     D  
Sbjct: 1045 YQGIMDKDEEKPG--KSSGPPRLGELTVTDRTSDSLLLRWTVPEGEFDSFVIQYKDRDGQ 1102

Query: 943  PVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTA------QQTTK 996
            P  +P E  QR  +       +T L PG  Y F ++     +   PL A      Q    
Sbjct: 1103 PQVVPVEGPQRSAV-------ITSLDPGRKYKFVLYGFVGKKRHGPLVAEAKILPQSDPS 1155

Query: 997  LDAPT---NLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPL 1053
               P    NL   + T  ++ + WT P  Q   + +     R G+P+   V      + +
Sbjct: 1156 PGTPPHLGNLWVTDPTPDSLHLSWTVPEGQFDTFMVQYR-DRDGRPQVVPVEGPERSFVV 1214

Query: 1054 RNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYN-------------TEVTE 1100
             +L P  +Y  +L  I   +     T   TT       PP               T VT 
Sbjct: 1215 SSLDPDHKYRFTLFGIANKKRYGPLTADGTTAPERKEEPPRPEFLEQPLLGELTVTGVTP 1274

Query: 1101 TTIVITWTPA--PRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRD 1158
             ++ ++WT A  P   F +  + +QG      V  D   + V GL P  +Y   +  LR 
Sbjct: 1275 DSLRLSWTVAQGPFDSFMVQYKDAQGQPQAVPVAGDENEVTVPGLDPDRKYKMNLYGLR- 1333

Query: 1159 GQERDAPIVNKVVTPLSP---------PTNLHLEA-----NPDTGVLTVSWERSTTPDIT 1204
            G++R  P    VV   +P         PT L  EA      P  G LTV+    ++PD  
Sbjct: 1334 GRQRVGP--ESVVAKTAPQEDVDETPSPTELGTEAPESPEEPLLGELTVT---GSSPDSL 1388

Query: 1205 GYRIT---------TTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKE 1255
                T         T     + G      V   +S  T   L PG +Y + +Y + + + 
Sbjct: 1389 SLFWTVPQGSFDSFTVQYKDRDGRPRAVRVGGKESEVTVGGLEPGHKYKMHLYGLHEGQR 1448

Query: 1256 SVPISDTIIPA-----VPPPTD---------LRFTNIGPDTMRVTWAPPPSIDLTNFLVR 1301
              P+S   + A      PP T+         L  T++ P+++ ++W  P      +F+V+
Sbjct: 1449 VGPVSAVGVTAPQQEETPPATESPLEPRLGELTVTDVTPNSVGLSWTVPEG-QFDSFIVQ 1507

Query: 1302 YSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLR---------- 1351
            Y     +  V  + ++     V + NL P  +Y +++  +++     PL           
Sbjct: 1508 YKDKDGQPQV--VPVAADQREVTVYNLEPERKYKMNMYGLHDGQRMGPLSVVIVTAPLPP 1565

Query: 1352 ----GRQKTGLDSPTG-IDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRV 1406
                   K  L+   G +  +DIT +S  + W  P      + +++      G+P+   V
Sbjct: 1566 APATEASKPPLEPRLGELTVTDITPDSVGLSWTVPEGEFDSFVVQYKDR--DGQPQVVPV 1623

Query: 1407 PHSRNSITLTNLTPGTEYVVSIVAL-NGREESPLLIGQQSTVSD------VPR--DLEVV 1457
               +  +T+ +L P  +Y   +  + +G+  SP+ +  ++           PR  +L V 
Sbjct: 1624 AADQREVTIPDLEPSRKYKFLLFGIQDGKRRSPVSVEAKTVARGDASPGAPPRLGELWVT 1683

Query: 1458 AATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTIT 1517
              TP SL +SW  P      + + + +  G   V    V G + + T++ L  G  Y   
Sbjct: 1684 DPTPDSLRLSWTVPEGQFDSFVVQFKDKDGPQVVP---VEGHERSVTVTPLDAGRKYRFL 1740

Query: 1518 VYAVTGRGDSPASSKPISINYRTEID--------KP---SQMQVTDVQDNSISVKWLPSS 1566
            +Y + G+      +   +   R+ +D        KP    ++QVT V  NS+ + W    
Sbjct: 1741 LYGLLGKKRHGPLTADGTTEARSAMDDTGTKRPPKPRLGEELQVTTVTQNSVGLSWTVPE 1800

Query: 1567 SPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQ 1626
                 + V    ++G  P      G    E+++ GL P   Y + +Y  +      P+  
Sbjct: 1801 GQFDSFVVQYKDRDGQ-PQVVPVEG-SLREVSVPGLDPAHRYKLLLYGLHHGKRVGPISA 1858

Query: 1627 TAVT----------NIDRPKG-------LAFTDVDVDSIKIAWESPQGQVSRYRVTYSSP 1669
             A+T              P         L   +    ++ ++W   +G+   + + Y+  
Sbjct: 1859 VAITAGREETETETTAPTPPAPEPHLGELTVEEATSHTLHLSWMVTEGEFDSFEIQYTD- 1917

Query: 1670 EDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLI------------GT 1717
             DG  ++     G+ +   L GL     Y V++    D     P+               
Sbjct: 1918 RDGQLQMVRI-GGDRNDITLSGLESDHRYLVTLYGFSDGKHVGPVHVEALTVPEEEKPSE 1976

Query: 1718 QSTAIPAPT------DLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLA 1771
              TA P P       +L  T  TP SLS  WT P  Q   + V+   +   G  K + + 
Sbjct: 1977 PPTATPEPPIKPRLGELTVTDATPDSLSLSWTVPEGQFDHFLVQY--RNGDGQPKAVRVP 2034

Query: 1772 PDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGV-VTTLENVSP---------PRRAR 1821
                 V +SGL    KY++++Y         P   V VT  E  +P         P  A 
Sbjct: 2035 GHEEGVTISGLEPDHKYKMNLYGFHGGQRMGPVSVVGVTAAEEETPSPTEPSMEAPEPAE 2094

Query: 1822 --------VTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGL 1873
                    VT ++  ++++SW         F V     +G+  + R +  +    T+ GL
Sbjct: 2095 EPLLGELTVTGSSPDSLSLSWTVPQGRFDSFTVQYKDRDGRPQVVR-VGGEESEVTVGGL 2153

Query: 1874 QPGTDYKIYLYTLNDNARSSPVVIDASTA-----IDAP------SNLRFLATTPNSLLVS 1922
            +PG  YK++LY L++  R  PV     TA      DAP        +     T +SL +S
Sbjct: 2154 EPGRKYKMHLYGLHEGRRVGPVSAVGVTAPEEESPDAPLAKLRLGQMTVRDITSDSLSLS 2213

Query: 1923 WQPPRARITGYIIKYEKPGSPPREV-VPRPRPGVTEATITGLEPGTEYTIYVIALKNNQK 1981
            W  P  +   ++++++     P+ V VP    GV   TI+GLEP  +Y + +      Q+
Sbjct: 2214 WTVPEGQFDHFLVQFKNGDGQPKAVRVPGHEDGV---TISGLEPDHKYKMNLYGFHGGQR 2270

Query: 1982 SEPLIGRKKTVQKTPFVTHPGYDTGNGIQLPGTSGQQPSVGQQMIFEEHGFRRTTPPTTA 2041
              P+            +T PG D                       EE     T PPT  
Sbjct: 2271 VGPV--------SAVGLTAPGKD-----------------------EEMAPASTEPPTPE 2299

Query: 2042 TPIRHRPRPYPPNVGQEALSQTTISWAPFQDTSEYIISCHPVGTDEEPLQFRVPGTSTSA 2101
             PI  +PR     V        ++SW   +   ++ +  +  G D +P   RVPG     
Sbjct: 2300 PPI--KPRLEELTVTDATPDSLSLSWTVPEGQFDHFLVQYKNG-DGQPKATRVPGHEDRV 2356

Query: 2102 TLTGLTRGATYNIIVEALKDQQR 2124
            T++GL     Y + +      QR
Sbjct: 2357 TISGLEPDNKYKMNLYGFHGGQR 2379



 Score =  224 bits (571), Expect = 8e-58
 Identities = 304/1427 (21%), Positives = 520/1427 (36%), Gaps = 231/1427 (16%)

Query: 900  GTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGE--HGQRLPIS 957
            G    + VP+   ++   + +  V   WTP    V  Y +  IP           R+P S
Sbjct: 742  GEDCGEEVPTIEGMRMHLLEETTVRTEWTPAPGPVDAYEIQFIPTTEGASPPFTARVPSS 801

Query: 958  RNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRW 1017
             + + +  GL+PG  Y   V A+       P +   TT +D P +L+ V  T +T+ + W
Sbjct: 802  ASAYDQ-RGLAPGQEYQVTVRALRGTSWGLPASKTITTMIDGPQDLRVVAVTPTTLELGW 860

Query: 1018 TPPRAQITGYRLTVGLTRRGQPR-QYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESP 1076
              P+A++   R  V     G  R +  V P      L +L P  EY V++ A +G   S 
Sbjct: 861  LRPQAEVD--RFVVSYVSAGNQRVRLEVPPEADGTLLTDLMPGVEYVVTVTAERGRAVSY 918

Query: 1077 KAT----------GVFTTLQPGSSIPPYNTEVTETTIV---------------------- 1104
             A+          G+  T        P  T+  +  ++                      
Sbjct: 919  PASVRANTGSSPLGLLGTTDEPPPSGPSTTQGAQAPLLQQRPQELGELRVLGRDETGRLR 978

Query: 1105 ITWTPAPR--IGFKLGVRPSQGGEAPREV-TSDSGSIVVSGLTPGVEYVYTIQVLRDGQE 1161
            + WT  P     F+L +R  +G  A  EV   D    +V    PG  Y  ++  +  G +
Sbjct: 979  VVWTAQPDTFAYFQLRMRVPEGPGAHEEVLPGDVRQALVPPPPPGTPYELSLHGVPPGGK 1038

Query: 1162 RDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERS-------TTPDITGYRITTTPTN 1214
               PI+ + +              P  G LTV+   S       T P+   +        
Sbjct: 1039 PSDPIIYQGIMDKDEEKPGKSSGPPRLGELTVTDRTSDSLLLRWTVPE-GEFDSFVIQYK 1097

Query: 1215 GQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPI--------SDTIIPA 1266
             + G      V   Q S    +L PG +Y   +Y     K   P+             P 
Sbjct: 1098 DRDGQPQVVPVEGPQRSAVITSLDPGRKYKFVLYGFVGKKRHGPLVAEAKILPQSDPSPG 1157

Query: 1267 VPPPT-DLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVL 1325
             PP   +L  T+  PD++ ++W  P       F+V+Y        V  + +   + + V+
Sbjct: 1158 TPPHLGNLWVTDPTPDSLHLSWTVPEG-QFDTFMVQYRDRDGRPQV--VPVEGPERSFVV 1214

Query: 1326 TNLLPGTEYVVSVSSVYEQHESTPLRGRQKTG------------LDSPT--GIDFSDITA 1371
            ++L P  +Y  ++  +  +    PL     T             L+ P    +  + +T 
Sbjct: 1215 SSLDPDHKYRFTLFGIANKKRYGPLTADGTTAPERKEEPPRPEFLEQPLLGELTVTGVTP 1274

Query: 1372 NSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVAL 1431
            +S  + W   +     + +++  +   G+P+   V    N +T+  L P  +Y +++  L
Sbjct: 1275 DSLRLSWTVAQGPFDSFMVQY--KDAQGQPQAVPVAGDENEVTVPGLDPDRKYKMNLYGL 1332

Query: 1432 NGREE--------------------SPLLIGQQSTVS---DVPRDLEVVAATPTSLLISW 1468
             GR+                     SP  +G ++  S    +  +L V  ++P SL + W
Sbjct: 1333 RGRQRVGPESVVAKTAPQEDVDETPSPTELGTEAPESPEEPLLGELTVTGSSPDSLSLFW 1392

Query: 1469 DAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAV-TGRGDS 1527
              P  +   + + Y +  G    +   V G +S  T+ GL+PG  Y + +Y +  G+   
Sbjct: 1393 TVPQGSFDSFTVQYKDRDGRP--RAVRVGGKESEVTVGGLEPGHKYKMHLYGLHEGQRVG 1450

Query: 1528 PASSKPISINYRTEI---------DKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTP 1578
            P S+  ++   + E           +  ++ VTDV  NS+ + W         + V    
Sbjct: 1451 PVSAVGVTAPQQEETPPATESPLEPRLGELTVTDVTPNSVGLSWTVPEGQFDSFIVQYKD 1510

Query: 1579 KNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE---------SQPLVQTAV 1629
            K+  G  +      DQ E+T+  L+P  +Y +++Y  +             + PL     
Sbjct: 1511 KD--GQPQVVPVAADQREVTVYNLEPERKYKMNMYGLHDGQRMGPLSVVIVTAPLPPAPA 1568

Query: 1630 TNIDRPK------GLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFP-APDG 1682
            T   +P        L  TD+  DS+ ++W  P+G+   + V Y    DG  ++ P A D 
Sbjct: 1569 TEASKPPLEPRLGELTVTDITPDSVGLSWTVPEGEFDSFVVQYKD-RDGQPQVVPVAADQ 1627

Query: 1683 EEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQST---------AIPAPTDLKFTQV 1733
             E T  +  L P  +Y   +  + D     P+     T         A P   +L  T  
Sbjct: 1628 REVT--IPDLEPSRKYKFLLFGIQDGKRRSPVSVEAKTVARGDASPGAPPRLGELWVTDP 1685

Query: 1734 TPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVY 1793
            TP SL   WT P  Q   + V+   K+K GP + + +     SV V+ L    KY   +Y
Sbjct: 1686 TPDSLRLSWTVPEGQFDSFVVQF--KDKDGP-QVVPVEGHERSVTVTPLDAGRKYRFLLY 1742

Query: 1794 ALKDTLTSRP--------AQGVVTTLENVSPPR-----RARVTDATETTITISWRTKTET 1840
             L       P        A+  +       PP+       +VT  T+ ++ +SW      
Sbjct: 1743 GLLGKKRHGPLTADGTTEARSAMDDTGTKRPPKPRLGEELQVTTVTQNSVGLSWTVPEGQ 1802

Query: 1841 ITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDAS 1900
               F V     +GQ P    ++  +R  ++ GL P   YK+ LY L+   R  P+   A 
Sbjct: 1803 FDSFVVQYKDRDGQ-PQVVPVEGSLREVSVPGLDPAHRYKLLLYGLHHGKRVGPISAVAI 1861

Query: 1901 TAIDAPSNLRFLATTP-----------------NSLLVSWQPPRARITGYIIKY-EKPGS 1942
            TA    +     A TP                 ++L +SW         + I+Y ++ G 
Sbjct: 1862 TAGREETETETTAPTPPAPEPHLGELTVEEATSHTLHLSWMVTEGEFDSFEIQYTDRDGQ 1921

Query: 1943 PPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQKTPFVTHPG 2002
                 +   R    + T++GLE    Y + +    + +   P+     TV +        
Sbjct: 1922 LQMVRIGGDR---NDITLSGLESDHRYLVTLYGFSDGKHVGPVHVEALTVPEE------- 1971

Query: 2003 YDTGNGIQLPGTSGQQPSVGQQMIFEEHGFRRTTPPTTATPIRHRPRPYPPNVGQEALSQ 2062
                          ++PS                 P TATP      P  P +G+  ++ 
Sbjct: 1972 --------------EKPS----------------EPPTATP----EPPIKPRLGELTVTD 1997

Query: 2063 TT-----ISWAPFQDTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVE 2117
             T     +SW   +   ++ +  +  G D +P   RVPG     T++GL     Y + + 
Sbjct: 1998 ATPDSLSLSWTVPEGQFDHFLVQYRNG-DGQPKAVRVPGHEEGVTISGLEPDHKYKMNLY 2056

Query: 2118 ALKDQQRHKVREEVVTVG-NSVNEGLNQPTDDSCFDPYTVSHYAVGD 2163
                 QR      V  VG  +  E    PT+ S   P       +G+
Sbjct: 2057 GFHGGQR---MGPVSVVGVTAAEEETPSPTEPSMEAPEPAEEPLLGE 2100



 Score =  220 bits (560), Expect = 1e-56
 Identities = 303/1380 (21%), Positives = 520/1380 (37%), Gaps = 232/1380 (16%)

Query: 822  VDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTEL--NLPETANSVTLSDLQPGVQYNIT 879
            +++T++   W+    P+  Y I + P+ EG+S      +P +A++     L PG +Y +T
Sbjct: 760  LEETTVRTEWTPAPGPVDAYEIQFIPTTEGASPPFTARVPSSASAYDQRGLAPGQEYQVT 819

Query: 880  IYAVEENQESTPVVIQQETTGTPRSDTVPS----PRDLQFVEVTDVKVTIMWTPPESAVT 935
            + A           ++  + G P S T+ +    P+DL+ V VT   + + W  P++ V 
Sbjct: 820  VRA-----------LRGTSWGLPASKTITTMIDGPQDLRVVAVTPTTLELGWLRPQAEVD 868

Query: 936  GYRVDVIPVNLPGEHGQRLPISRNTFAE-VTGLSPGVTYYFKVFA-----------VSHG 983
             + V  +     G    RL +        +T L PGV Y   V A           V   
Sbjct: 869  RFVVSYVSA---GNQRVRLEVPPEADGTLLTDLMPGVEYVVTVTAERGRAVSYPASVRAN 925

Query: 984  RESKPLTAQQTTKLDAPTNLQFVNETDSTVL----------------------VRWTPPR 1021
              S PL    TT    P+         + +L                      V WT   
Sbjct: 926  TGSSPLGLLGTTDEPPPSGPSTTQGAQAPLLQQRPQELGELRVLGRDETGRLRVVWTAQP 985

Query: 1022 AQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIK--GNQESPKA- 1078
                 ++L + +       +  +   V +  +    P + Y +SL  +   G    P   
Sbjct: 986  DTFAYFQLRMRVPEGPGAHEEVLPGDVRQALVPPPPPGTPYELSLHGVPPGGKPSDPIIY 1045

Query: 1079 TGVF--TTLQPG-SSIPPYNTEVTET-----TIVITWT-PAPRI-GFKLGVRPSQGGEAP 1128
             G+      +PG SS PP   E+T T     ++++ WT P      F +  +   G    
Sbjct: 1046 QGIMDKDEEKPGKSSGPPRLGELTVTDRTSDSLLLRWTVPEGEFDSFVIQYKDRDGQPQV 1105

Query: 1129 REVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKV-VTPLSPPTNLHLEANPD 1187
              V     S V++ L PG +Y + +     G++R  P+V +  + P S P+       P 
Sbjct: 1106 VPVEGPQRSAVITSLDPGRKYKFVLYGF-VGKKRHGPLVAEAKILPQSDPSP---GTPPH 1161

Query: 1188 TGVLTVSWERSTTPDITGYRITTTPTNGQ-----------QGNSLEEVVHADQSSCTFDN 1236
             G L   W    TPD     ++ T   GQ            G      V   + S    +
Sbjct: 1162 LGNL---WVTDPTPD--SLHLSWTVPEGQFDTFMVQYRDRDGRPQVVPVEGPERSFVVSS 1216

Query: 1237 LSPGLEYNVSVYTVKDDKESVPIS--DTIIP--AVPPPT----------DLRFTNIGPDT 1282
            L P  +Y  +++ + + K   P++   T  P     PP           +L  T + PD+
Sbjct: 1217 LDPDHKYRFTLFGIANKKRYGPLTADGTTAPERKEEPPRPEFLEQPLLGELTVTGVTPDS 1276

Query: 1283 MRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLP------------ 1330
            +R++W         +F+V+Y   + +     + ++  +N V +  L P            
Sbjct: 1277 LRLSWTVAQG-PFDSFMVQYKDAQGQPQA--VPVAGDENEVTVPGLDPDRKYKMNLYGLR 1333

Query: 1331 -----GTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTG--------IDFSDITANSFTVH 1377
                 G E VV+ ++  E  + TP     + G ++P          +  +  + +S ++ 
Sbjct: 1334 GRQRVGPESVVAKTAPQEDVDETP--SPTELGTEAPESPEEPLLGELTVTGSSPDSLSLF 1391

Query: 1378 WIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEY------------- 1424
            W  P+ +   + +++      GRPR  RV    + +T+  L PG +Y             
Sbjct: 1392 WTVPQGSFDSFTVQYKDR--DGRPRAVRVGGKESEVTVGGLEPGHKYKMHLYGLHEGQRV 1449

Query: 1425 -VVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYG 1483
              VS V +   ++       +S +     +L V   TP S+ +SW  P      + + Y 
Sbjct: 1450 GPVSAVGVTAPQQEETPPATESPLEPRLGELTVTDVTPNSVGLSWTVPEGQFDSFIVQYK 1509

Query: 1484 ETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAV-TGRGDSPAS----SKPISINY 1538
            +  G    Q   V   +   T+  L+P   Y + +Y +  G+   P S    + P+    
Sbjct: 1510 DKDGQP--QVVPVAADQREVTVYNLEPERKYKMNMYGLHDGQRMGPLSVVIVTAPLPPAP 1567

Query: 1539 RTEIDKP------SQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGP 1592
             TE  KP       ++ VTD+  +S+ + W         + V    K+  G  +      
Sbjct: 1568 ATEASKPPLEPRLGELTVTDITPDSVGLSWTVPEGEFDSFVVQY--KDRDGQPQVVPVAA 1625

Query: 1593 DQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTA--VTNIDRPKG-------LAFTDV 1643
            DQ E+TI  L+P+ +Y   ++         P+   A  V   D   G       L  TD 
Sbjct: 1626 DQREVTIPDLEPSRKYKFLLFGIQDGKRRSPVSVEAKTVARGDASPGAPPRLGELWVTDP 1685

Query: 1644 DVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVV 1703
              DS++++W  P+GQ   + V +   +DG  ++ P  +G E +  +  L  G +Y   + 
Sbjct: 1686 TPDSLRLSWTVPEGQFDSFVVQFKD-KDG-PQVVPV-EGHERSVTVTPLDAGRKYRFLLY 1742

Query: 1704 ALHDDMESQPLIGTQSTAI------------PAP---TDLKFTQVTPTSLSAQWTPPNVQ 1748
             L       PL    +T              P P    +L+ T VT  S+   WT P  Q
Sbjct: 1743 GLLGKKRHGPLTADGTTEARSAMDDTGTKRPPKPRLGEELQVTTVTQNSVGLSWTVPEGQ 1802

Query: 1749 LTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVV 1808
               + V+   K++ G  + + +      V V GL  A +Y++ +Y L       P   V 
Sbjct: 1803 FDSFVVQY--KDRDGQPQVVPVEGSLREVSVPGLDPAHRYKLLLYGLHHGKRVGPISAVA 1860

Query: 1809 -------TTLENVSPPRRA--------RVTDATETTITISWRTKTETITGFQVDAVPANG 1853
                   T  E  +P   A         V +AT  T+ +SW         F++     +G
Sbjct: 1861 ITAGREETETETTAPTPPAPEPHLGELTVEEATSHTLHLSWMVTEGEFDSFEIQYTDRDG 1920

Query: 1854 QTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDA------------ST 1901
            Q  + R I  D    T++GL+    Y + LY  +D     PV ++A             T
Sbjct: 1921 QLQMVR-IGGDRNDITLSGLESDHRYLVTLYGFSDGKHVGPVHVEALTVPEEEKPSEPPT 1979

Query: 1902 AIDAP------SNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREV-VPRPRPG 1954
            A   P        L     TP+SL +SW  P  +   ++++Y      P+ V VP    G
Sbjct: 1980 ATPEPPIKPRLGELTVTDATPDSLSLSWTVPEGQFDHFLVQYRNGDGQPKAVRVPGHEEG 2039

Query: 1955 VTEATITGLEPGTEYTIYVIALKNNQKSEP--LIGRKKTVQKTPFVTHPGYDTGNGIQLP 2012
            V   TI+GLEP  +Y + +      Q+  P  ++G     ++TP  T P  +     + P
Sbjct: 2040 V---TISGLEPDHKYKMNLYGFHGGQRMGPVSVVGVTAAEEETPSPTEPSMEAPEPAEEP 2096



 Score =  103 bits (257), Expect = 2e-21
 Identities = 100/428 (23%), Positives = 166/428 (38%), Gaps = 60/428 (14%)

Query: 1613 YAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDG 1672
            YA    GE  P ++          G+    ++  +++  W    G V  Y + +    +G
Sbjct: 740  YAGEDCGEEVPTIE----------GMRMHLLEETTVRTEWTPAPGPVDAYEIQFIPTTEG 789

Query: 1673 IHELFPAPDGEEDTA-ELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFT 1731
                F A      +A + +GL PG EY V+V AL       P   T +T I  P DL+  
Sbjct: 790  ASPPFTARVPSSASAYDQRGLAPGQEYQVTVRALRGTSWGLPASKTITTMIDGPQDLRVV 849

Query: 1732 QVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVS 1791
             VTPT+L   W  P  ++   R  V+          + + P++   +++ LM   +Y V+
Sbjct: 850  AVTPTTLELGWLRPQAEVD--RFVVSYVSAGNQRVRLEVPPEADGTLLTDLMPGVEYVVT 907

Query: 1792 VYALKDTLTSRPAQ----------GVVTTLENVSPP--------------------RRAR 1821
            V A +    S PA           G++ T +   P                        R
Sbjct: 908  VTAERGRAVSYPASVRANTGSSPLGLLGTTDEPPPSGPSTTQGAQAPLLQQRPQELGELR 967

Query: 1822 VTDATET-TITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYK 1880
            V    ET  + + W  + +T   FQ+      G    +  +  DVR   +    PGT Y+
Sbjct: 968  VLGRDETGRLRVVWTAQPDTFAYFQLRMRVPEGPGAHEEVLPGDVRQALVPPPPPGTPYE 1027

Query: 1881 IYLYTLNDNAR-SSPVVIDASTAID--------APSNLRFLAT---TPNSLLVSWQPPRA 1928
            + L+ +    + S P++       D         P  L  L     T +SLL+ W  P  
Sbjct: 1028 LSLHGVPPGGKPSDPIIYQGIMDKDEEKPGKSSGPPRLGELTVTDRTSDSLLLRWTVPEG 1087

Query: 1929 RITGYIIKY-EKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIG 1987
                ++I+Y ++ G P  +VVP   P    A IT L+PG +Y   +      ++  PL+ 
Sbjct: 1088 EFDSFVIQYKDRDGQP--QVVPVEGP-QRSAVITSLDPGRKYKFVLYGFVGKKRHGPLVA 1144

Query: 1988 RKKTVQKT 1995
              K + ++
Sbjct: 1145 EAKILPQS 1152


>gi|93141049 collagen, type XII, alpha 1 short isoform precursor [Homo
            sapiens]
          Length = 1899

 Score =  296 bits (757), Expect = 2e-79
 Identities = 244/929 (26%), Positives = 413/929 (44%), Gaps = 43/929 (4%)

Query: 997  LDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNL 1056
            L+AP+NL     T  +  V WTPP   +  Y++       G+ +++ V    +   L++L
Sbjct: 221  LEAPSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSGGKRQEFYVSRMETSTVLKDL 280

Query: 1057 QPASEYTVSLVAIKGNQESPKATGVFTTLQ-PGSSIPPYNTEVTETTIVITWTP-APRIG 1114
            +P +EY V++ ++  ++ S    G   TL  P  S+  Y  +V  TT+ + W P     G
Sbjct: 281  KPETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVVSLNIY--DVGPTTMHVQWQPVGGATG 338

Query: 1115 FKLGVRPSQGGEAPREVTSDSGSIV----VSGLTPGVEYVYTIQVLRDGQERDAPIVNKV 1170
            + L  +P +  E  R      G  V    ++ L P  EY  T+Q +      +   V +V
Sbjct: 339  YILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEPVTVREV 398

Query: 1171 VTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQS 1230
              PL  P +L L  +     + V WE    P      I    T  +    +E  V   ++
Sbjct: 399  TLPLPRPQDLKLR-DVTHSTMNVFWE--PVPGKVRKYIVRYKTPEEDVKEVE--VDRSET 453

Query: 1231 SCTFDNLSPGLEYNVSVYTVKDDKESVPIS--DTIIPAVPPPTDLRFTNIGPDTMRVTWA 1288
            S +  +L     Y VSV  V D+ ES P++  +T  P VP PT+L+ T +  +  R TW 
Sbjct: 454  STSLKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRP-VPAPTNLKITEVTSEGFRGTWD 512

Query: 1289 PPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVY-EQHES 1347
               S D++ + + ++P     D  E  ++  +N +V  NL P T Y VS++++Y ++ ES
Sbjct: 513  HGAS-DVSLYRITWAPF-GSSDKMETILNGDENTLVFENLNPNTIYEVSITAIYPDESES 570

Query: 1348 TPLRGRQKT--------GLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSG 1399
              L G ++T            P  +   + T+NS TV W      +  YRI + P    G
Sbjct: 571  DDLIGSERTLPILTTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEG 630

Query: 1400 RPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVS-DVPRDLEVVA 1458
              +   +   +NS+ L  L P T Y +++ +L    E   + G+  T   +  R+L V  
Sbjct: 631  NEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRVYD 690

Query: 1459 ATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITV 1518
             + ++L + WD      R Y++ Y    G  P +   +PG+ + A +  L+P   YT+TV
Sbjct: 691  PSTSTLNVRWDHAEGNPRQYKLFYAPAAG-GPEELVPIPGNTNYAILRNLQPDTSYTVTV 749

Query: 1519 YAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTP 1578
              V   GD   +S       R        +QV +   NS+ V+W P+  PV  YRV  +P
Sbjct: 750  VPVYTEGDGGRTSDTGRTLMR---GLARNVQVYNPTPNSLDVRWDPAPGPVLQYRVVYSP 806

Query: 1579 KNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPL-VQTAVTNIDRPKG 1637
             +G  P+++     +   + +E L P   Y V++ A    GE  P   Q        P+ 
Sbjct: 807  VDGTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGRTLPRSGPRN 866

Query: 1638 LAFTDVDVDSIKIAWESPQGQVSRYRVTYS-SPEDGIHELFPAPDGEEDTAELQGLRPGS 1696
            L       +S+ +AW+   G V +YR+ YS +  D I E    P G  +   LQ L+P +
Sbjct: 867  LRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVP-GRRNNVILQPLQPDT 925

Query: 1697 EYTVSVVALHDDMESQPLIGT-QSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVR 1755
             Y ++V+A+++D +   L G  ++  +  P ++  +    T     W P    + GY++ 
Sbjct: 926  PYKITVIAVYEDGDGGHLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPSPVLGYKIV 985

Query: 1756 VTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLE-NV 1814
              P     PM+      + +S  +  L  +T Y+V+VYA  D+  S P     TTL  NV
Sbjct: 986  YKPVGSNEPMEA--FVGEMTSYTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQGTTLYLNV 1043

Query: 1815 SPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQ 1874
            +  +  ++      T  + W +     T +++   PA+G    + T++    S+  TGL 
Sbjct: 1044 TDLKTYQI---GWDTFCVKW-SPHRAATSYRLKLSPADGTRGQEITVRGSETSHCFTGLS 1099

Query: 1875 PGTDYKIYLYTLNDNARSSPVVIDASTAI 1903
            P TDY + ++    N     V +   T +
Sbjct: 1100 PDTDYGVTVFVQTPNLEGPGVSVKEHTTV 1128



 Score =  286 bits (733), Expect = 1e-76
 Identities = 233/844 (27%), Positives = 381/844 (45%), Gaps = 32/844 (3%)

Query: 1166 IVNKVVTP--LSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEE 1223
            + N V  P  L  P+NL +          VSW    +  +  Y++   P +G  G   E 
Sbjct: 211  LCNSVKGPGDLEAPSNLVISERTHRS-FRVSWT-PPSDSVDRYKVEYYPVSG--GKRQEF 266

Query: 1224 VVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRFTNIGPDTM 1283
             V   ++S    +L P  EY V+VY+V +D+ S P+  T      P   L   ++GP TM
Sbjct: 267  YVSRMETSTVLKDLKPETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVVSLNIYDVGPTTM 326

Query: 1284 RVTWAPPPSIDLTNFLVRYSPVKNEEDVA--ELSISPSDNAVVLTNLLPGTEYVVSVSSV 1341
             V W P      T +++ Y PVK+ E     E+ + P+ N + LT+L+P TEY V+V +V
Sbjct: 327  HVQWQPVGGA--TGYILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAV 384

Query: 1342 YEQHESTPLRGRQKT-GLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHH-PEHFSG 1399
                 S P+  R+ T  L  P  +   D+T ++  V W      +  Y +R+  PE    
Sbjct: 385  LHDLTSEPVTVREVTLPLPRPQDLKLRDVTHSTMNVFWEPVPGKVRKYIVRYKTPEE--- 441

Query: 1400 RPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVS-DVPRDLEVVA 1458
              +E  V  S  S +L +L   T Y VS+ A++   ESP +  Q++T     P +L++  
Sbjct: 442  DVKEVEVDRSETSTSLKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPAPTNLKITE 501

Query: 1459 ATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITV 1518
             T      +WD  A  V  YRIT+   G +S   E  + G ++T     L P   Y +++
Sbjct: 502  VTSEGFRGTWDHGASDVSLYRITWAPFG-SSDKMETILNGDENTLVFENLNPNTIYEVSI 560

Query: 1519 YAV----TGRGDSPASSKPISINYRTEIDK--PSQMQVTDVQDNSISVKWLPSSSPVTGY 1572
             A+    +   D   S + + I   T+  K  P  +QV +   NS++VKW P+S  V  Y
Sbjct: 561  TAIYPDESESDDLIGSERTLPI-LTTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKY 619

Query: 1573 RVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTN- 1631
            R+T  P  G G  +T T G  Q  + ++ L+P   Y ++V +  P GE   +     T  
Sbjct: 620  RITYQPSTGEGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKP 679

Query: 1632 IDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQG 1691
            ++  + L   D    ++ + W+  +G   +Y++ Y+    G  EL P P G  + A L+ 
Sbjct: 680  LNTVRNLRVYDPSTSTLNVRWDHAEGNPRQYKLFYAPAAGGPEELVPIP-GNTNYAILRN 738

Query: 1692 LRPGSEYTVSVVALHDDMESQPLIGTQSTAIPA-PTDLKFTQVTPTSLSAQWTPPNVQLT 1750
            L+P + YTV+VV ++ + +      T  T +     +++    TP SL  +W P    + 
Sbjct: 739  LQPDTSYTVTVVPVYTEGDGGRTSDTGRTLMRGLARNVQVYNPTPNSLDVRWDPAPGPVL 798

Query: 1751 GYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTT 1810
             YRV  +P + T P + I +  ++  V +  L+  T Y V++ AL       P+     T
Sbjct: 799  QYRVVYSPVDGTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGRT 858

Query: 1811 LENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTI 1870
            L   S PR  RV   T  +++++W      +  +++   P  G    + T  P  R+  I
Sbjct: 859  LPR-SGPRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVPGRRNNVI 917

Query: 1871 -TGLQPGTDYKIYLYTLNDNARSSPVVIDAST-AIDAPSNLRFLATTPNSLLVSWQPPRA 1928
               LQP T YKI +  + ++     +  +  T  +  P N+           VSW P  +
Sbjct: 918  LQPLQPDTPYKITVIAVYEDGDGGHLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPS 977

Query: 1929 RITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGR 1988
             + GY I Y+  GS   E +      +T  T+  L P T Y + V A  ++  S PL  +
Sbjct: 978  PVLGYKIVYKPVGS--NEPMEAFVGEMTSYTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQ 1035

Query: 1989 KKTV 1992
              T+
Sbjct: 1036 GTTL 1039



 Score =  278 bits (711), Expect = 4e-74
 Identities = 244/917 (26%), Positives = 395/917 (43%), Gaps = 53/917 (5%)

Query: 728  VTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYI 787
            ++E T  SF VSW   SD+V  ++VEY     G + Q   +    TS  + DL P  +Y+
Sbjct: 229  ISERTHRSFRVSWTPPSDSVDRYKVEY-YPVSGGKRQEFYVSRMETSTVLKDLKPETEYV 287

Query: 788  VNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSP 847
            VNVY + ED E S  L  ++ T P       +  V  T++ V+W +P    TGY + Y P
Sbjct: 288  VNVYSVVED-EYSEPLKGTEKTLPVPVVSLNIYDVGPTTMHVQW-QPVGGATGYILSYKP 345

Query: 848  SVEGSST---ELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRS 904
              +   T   E+ L  T N + L+DL P  +Y +T+ AV  +  S PV +++ T   PR 
Sbjct: 346  VKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEPVTVREVTLPLPR- 404

Query: 905  DTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRN-TFAE 963
                 P+DL+  +VT   + + W P    V  Y   ++    P E  + + + R+ T   
Sbjct: 405  -----PQDLKLRDVTHSTMNVFWEPVPGKVRKY---IVRYKTPEEDVKEVEVDRSETSTS 456

Query: 964  VTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTK-LDAPTNLQFVNETDSTVLVRWTPPRA 1022
            +  L     Y   V AV    ES P+TAQ+TT+ + APTNL+    T       W    +
Sbjct: 457  LKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPAPTNLKITEVTSEGFRGTWDHGAS 516

Query: 1023 QITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQE-------S 1075
             ++ YR+T          +  +    +     NL P + Y VS+ AI  ++        S
Sbjct: 517  DVSLYRITWAPFGSSDKMETILNGDENTLVFENLNPNTIYEVSITAIYPDESESDDLIGS 576

Query: 1076 PKATGVFTTLQPGSSIPPYNTEV---TETTIVITWTPAP-RI-GFKLGVRPS--QGGEAP 1128
             +   + TT  P S   P N +V   T  ++ + W PA  R+  +++  +PS  +G E  
Sbjct: 577  ERTLPILTTQAPKSG--PRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQT 634

Query: 1129 REVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDT 1188
              +     S+V+  L P   Y  T+  L    E           PL+   NL +  +P T
Sbjct: 635  TTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRV-YDPST 693

Query: 1189 GVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVS-- 1246
              L V W+ +   +   Y++   P  G  G      +  + +     NL P   Y V+  
Sbjct: 694  STLNVRWDHA-EGNPRQYKLFYAPAAG--GPEELVPIPGNTNYAILRNLQPDTSYTVTVV 750

Query: 1247 -VYTVKDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPV 1305
             VYT  D   +     T++  +    +++  N  P+++ V W P P   +  + V YSPV
Sbjct: 751  PVYTEGDGGRTSDTGRTLMRGL--ARNVQVYNPTPNSLDVRWDPAPG-PVLQYRVVYSPV 807

Query: 1306 KNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKT-GLDSPTGI 1364
                    + +  +   V L  L+P T Y V++ ++Y   E  P   + +T     P  +
Sbjct: 808  DGTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGRTLPRSGPRNL 867

Query: 1365 DFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEY 1424
                 T NS +V W      +  YRI + P           VP  RN++ L  L P T Y
Sbjct: 868  RVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVPGRRNNVILQPLQPDTPY 927

Query: 1425 VVSIVALNGREESPLLIGQQSTVSDV-PRDLEVVAATPTSLLISWDAPAVTVRYYRITYG 1483
             ++++A+    +   L G   TV  + P+++ +     T   +SWD     V  Y+I Y 
Sbjct: 928  KITVIAVYEDGDGGHLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPSPVLGYKIVYK 987

Query: 1484 ETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEID 1543
              G N P++ F   G  ++ T+  L P   Y + VYA    G     S P++    T   
Sbjct: 988  PVGSNEPMEAFV--GEMTSYTLHNLNPSTTYDVNVYAQYDSG----LSVPLTDQGTTLYL 1041

Query: 1544 KPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQ 1603
              + ++   +  ++  VKW P  +  T YR+  +P +G    +    G  +T     GL 
Sbjct: 1042 NVTDLKTYQIGWDTFCVKWSPHRA-ATSYRLKLSPADGTRGQEITVRG-SETSHCFTGLS 1099

Query: 1604 PTVEYVVSVYAQNPSGE 1620
            P  +Y V+V+ Q P+ E
Sbjct: 1100 PDTDYGVTVFVQTPNLE 1116



 Score =  277 bits (709), Expect = 8e-74
 Identities = 256/949 (26%), Positives = 419/949 (44%), Gaps = 63/949 (6%)

Query: 1087 PGSSIPPYNTEVTETT---IVITWTPAPRI--GFKLGVRPSQGGEAPR-EVTSDSGSIVV 1140
            PG    P N  ++E T     ++WTP       +K+   P  GG+     V+    S V+
Sbjct: 218  PGDLEAPSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSGGKRQEFYVSRMETSTVL 277

Query: 1141 SGLTPGVEYVYTI-QVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERST 1199
              L P  EYV  +  V+ D  E   P+     T   P  +L++    D G  T+  +   
Sbjct: 278  KDLKPETEYVVNVYSVVED--EYSEPLKGTEKTLPVPVVSLNIY---DVGPTTMHVQWQP 332

Query: 1200 TPDITGYRITTTPTNGQQGNSLEEV-VHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVP 1258
                TGY ++  P    +    +EV +    +     +L P  EY V+V  V  D  S P
Sbjct: 333  VGGATGYILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEP 392

Query: 1259 IS--DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSI 1316
            ++  +  +P +P P DL+  ++   TM V W P P   +  ++VRY     EEDV E+ +
Sbjct: 393  VTVREVTLP-LPRPQDLKLRDVTHSTMNVFWEPVPG-KVRKYIVRYKTP--EEDVKEVEV 448

Query: 1317 SPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTG-LDSPTGIDFSDITANSFT 1375
              S+ +  L +L   T Y VSVS+V+++ ES P+  ++ T  + +PT +  +++T+  F 
Sbjct: 449  DRSETSTSLKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPAPTNLKITEVTSEGFR 508

Query: 1376 VHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGRE 1435
              W    + ++ YRI   P   S +  E  +    N++   NL P T Y VSI A+   E
Sbjct: 509  GTWDHGASDVSLYRITWAPFGSSDK-METILNGDENTLVFENLNPNTIYEVSITAIYPDE 567

Query: 1436 -ESPLLIGQQSTVSDV--------PRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETG 1486
             ES  LIG + T+  +        PR+L+V  AT  SL + WD  +  V+ YRITY  + 
Sbjct: 568  SESDDLIGSERTLPILTTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPST 627

Query: 1487 GNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVT-----GRGDSPASSKPISINYRTE 1541
            G    Q  T+ G +++  +  LKP   YTITV ++      GR      +KP++      
Sbjct: 628  GEGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNT----- 682

Query: 1542 IDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEG 1601
                  ++V D   ++++V+W  +      Y++   P  G GP +      +     +  
Sbjct: 683  ---VRNLRVYDPSTSTLNVRWDHAEGNPRQYKLFYAPAAG-GPEELVPIPGNTNYAILRN 738

Query: 1602 LQPTVEY---VVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQ 1658
            LQP   Y   VV VY +   G +    +T +  + R   +   +   +S+ + W+   G 
Sbjct: 739  LQPDTSYTVTVVPVYTEGDGGRTSDTGRTLMRGLAR--NVQVYNPTPNSLDVRWDPAPGP 796

Query: 1659 VSRYRVTYSSPEDGIH--ELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIG 1716
            V +YRV YS P DG    E    P G      L+ L P + Y+V++VAL+ D E  P   
Sbjct: 797  VLQYRVVYS-PVDGTRPSESIVVP-GNTRMVHLERLIPDTLYSVNLVALYSDGEGNPS-P 853

Query: 1717 TQSTAIP--APTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDS 1774
             Q   +P   P +L+    T  SLS  W   +  +  YR+  +P     P+ E    P  
Sbjct: 854  AQGRTLPRSGPRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGD-PIDEYTTVPGR 912

Query: 1775 -SSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITIS 1833
             ++V++  L   T Y+++V A+ +        G   T+  + PP+   ++D   T   +S
Sbjct: 913  RNNVILQPLQPDTPYKITVIAVYEDGDGGHLTGNGRTV-GLLPPQNIHISDEWYTRFRVS 971

Query: 1834 WRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSS 1893
            W      + G+++   P     P++  +  ++ SYT+  L P T Y + +Y   D+  S 
Sbjct: 972  WDPSPSPVLGYKIVYKPVGSNEPMEAFVG-EMTSYTLHNLNPSTTYDVNVYAQYDSGLSV 1030

Query: 1894 PVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRP 1953
            P+    +T     ++L+      ++  V W P RA  T Y +K   P    R      R 
Sbjct: 1031 PLTDQGTTLYLNVTDLKTYQIGWDTFCVKWSPHRA-ATSYRLKL-SPADGTRGQEITVRG 1088

Query: 1954 GVTEATITGLEPGTEYTIYVIALKNNQKSEPL-IGRKKTVQKTPFVTHP 2001
              T    TGL P T+Y + V     N +   + +    TV+ T   T P
Sbjct: 1089 SETSHCFTGLSPDTDYGVTVFVQTPNLEGPGVSVKEHTTVKPTEAPTEP 1137



 Score =  256 bits (655), Expect = 1e-67
 Identities = 254/947 (26%), Positives = 393/947 (41%), Gaps = 51/947 (5%)

Query: 812  DAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQ 871
            +AP +  + +    S  V W+ P   +  Y++ Y P   G   E  +     S  L DL+
Sbjct: 222  EAPSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSGGKRQEFYVSRMETSTVLKDLK 281

Query: 872  PGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE 931
            P  +Y + +Y+V E++ S P+       GT ++  VP    L   +V    + + W P  
Sbjct: 282  PETEYVVNVYSVVEDEYSEPL------KGTEKTLPVPVV-SLNIYDVGPTTMHVQWQPVG 334

Query: 932  SAVTGYRVDVIPV-----NLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRES 986
             A TGY +   PV       P E   RL  + N   ++T L P   Y   V AV H   S
Sbjct: 335  GA-TGYILSYKPVKDTEPTRPKE--VRLGPTVNDM-QLTDLVPNTEYAVTVQAVLHDLTS 390

Query: 987  KPLTAQQTT-KLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVG 1045
            +P+T ++ T  L  P +L+  + T ST+ V W P   ++  Y +    T     ++  V 
Sbjct: 391  EPVTVREVTLPLPRPQDLKLRDVTHSTMNVFWEPVPGKVRKY-IVRYKTPEEDVKEVEVD 449

Query: 1046 PSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVI 1105
             S +   L++L   + YTVS+ A+    ESP  T   TT    +      TEVT      
Sbjct: 450  RSETSTSLKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPAPTNLKITEVTSEGFRG 509

Query: 1106 TWTPAPRIGFKLGVRPSQGGEAPREVT---SDSGSIVVSGLTPGVEYVYTIQVLRD---- 1158
            TW           +  +  G + +  T    D  ++V   L P   Y  +I  +      
Sbjct: 510  TWDHGASDVSLYRITWAPFGSSDKMETILNGDENTLVFENLNPNTIYEVSITAIYPDESE 569

Query: 1159 -----GQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPT 1213
                 G ER  PI+     P S P NL +  N  +  LTV W+   +  +  YRIT  P+
Sbjct: 570  SDDLIGSERTLPILT-TQAPKSGPRNLQV-YNATSNSLTVKWD-PASGRVQKYRITYQPS 626

Query: 1214 NGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDT-IIPAVPPPTD 1272
             G +GN     +   Q+S     L P   Y ++V ++  D E   ++       +    +
Sbjct: 627  TG-EGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVRN 685

Query: 1273 LRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGT 1332
            LR  +    T+ V W      +   + + Y+P     +   + I  + N  +L NL P T
Sbjct: 686  LRVYDPSTSTLNVRWDHAEG-NPRQYKLFYAPAAGGPEEL-VPIPGNTNYAILRNLQPDT 743

Query: 1333 EYVVSVSSVYEQHESTPLRGRQKTGLDS-PTGIDFSDITANSFTVHWIAPRATITGYRIR 1391
             Y V+V  VY + +        +T +      +   + T NS  V W      +  YR+ 
Sbjct: 744  SYTVTVVPVYTEGDGGRTSDTGRTLMRGLARNVQVYNPTPNSLDVRWDPAPGPVLQYRVV 803

Query: 1392 HHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVAL-NGREESPLLIGQQSTVSDV 1450
            + P   +       VP +   + L  L P T Y V++VAL +  E +P     ++     
Sbjct: 804  YSPVDGTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGRTLPRSG 863

Query: 1451 PRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEF-TVPGSKSTATISGLK 1509
            PR+L V   T  SL ++WD     V+ YRI Y  T G+ P+ E+ TVPG ++   +  L+
Sbjct: 864  PRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGD-PIDEYTTVPGRRNNVILQPLQ 922

Query: 1510 PGVDYTITVYAVTGRGDSPASSKPISINYRT-EIDKPSQMQVTDVQDNSISVKWLPSSSP 1568
            P   Y ITV AV   GD       ++ N RT  +  P  + ++D       V W PS SP
Sbjct: 923  PDTPYKITVIAVYEDGD----GGHLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPSP 978

Query: 1569 VTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTA 1628
            V GY++   P     P +      + T  T+  L P+  Y V+VYAQ  SG S PL    
Sbjct: 979  VLGYKIVYKPVGSNEPMEAFVG--EMTSYTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQG 1036

Query: 1629 VTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAE 1688
             T       L    +  D+  + W SP    + YR+   SP DG         G E +  
Sbjct: 1037 TTLYLNVTDLKTYQIGWDTFCVKW-SPHRAATSYRLKL-SPADGTRGQEITVRGSETSHC 1094

Query: 1689 LQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTP 1735
              GL P ++Y V+V     ++E  P +  +      PT+      TP
Sbjct: 1095 FTGLSPDTDYGVTVFVQTPNLEG-PGVSVKEHTTVKPTEAPTEPPTP 1140



 Score =  200 bits (508), Expect = 2e-50
 Identities = 217/866 (25%), Positives = 356/866 (41%), Gaps = 75/866 (8%)

Query: 623  PNSHPIQWNAPQP-SHISKYILRWRPKNSVG--RWKEATIPGHLNSYTIKGLKPGVVYEG 679
            P +  +QW   QP    + YIL ++P       R KE  +   +N   +  L P   Y  
Sbjct: 323  PTTMHVQW---QPVGGATGYILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYA- 378

Query: 680  QLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSE-SVTEITASSFVV 738
              +++Q   H            TS PVT   VT       PL    +  + ++T S+  V
Sbjct: 379  --VTVQAVLHD----------LTSEPVTVREVT------LPLPRPQDLKLRDVTHSTMNV 420

Query: 739  SWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGE 798
             W      V  + V Y+  EE  +   +D   T+TS+   DL     Y V+V  + ++GE
Sbjct: 421  FWEPVPGKVRKYIVRYKTPEEDVKEVEVDRSETSTSLK--DLFSQTLYTVSVSAVHDEGE 478

Query: 799  QSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNL 858
               + +   T    AP +  + +V        W    + ++ YRI ++P       E  L
Sbjct: 479  SPPVTAQETTRPVPAPTNLKITEVTSEGFRGTWDHGASDVSLYRITWAPFGSSDKMETIL 538

Query: 859  PETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQE------TTGTPRSDTVPSPRD 912
                N++   +L P   Y ++I A+  ++  +  +I  E      TT  P+S     PR+
Sbjct: 539  NGDENTLVFENLNPNTIYEVSITAIYPDESESDDLIGSERTLPILTTQAPKS----GPRN 594

Query: 913  LQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVT 972
            LQ    T   +T+ W P    V  YR+   P    G         R     +  L P   
Sbjct: 595  LQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQTTTIGGRQNSVVLQKLKPDTP 654

Query: 973  YYFKVFAVSHGRESKPLTAQQTTK-LDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTV 1031
            Y   V ++    E   +T +  TK L+   NL+  + + ST+ VRW         Y+L  
Sbjct: 655  YTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRVYDPSTSTLNVRWDHAEGNPRQYKLFY 714

Query: 1032 GLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPG--S 1089
                 G      +  + +   LRNLQP + YTV++V +    +  + +    TL  G   
Sbjct: 715  APAAGGPEELVPIPGNTNYAILRNLQPDTSYTVTVVPVYTEGDGGRTSDTGRTLMRGLAR 774

Query: 1090 SIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSG------- 1142
            ++  YN   T  ++ + W PAP    +  V  S     P + T  S SIVV G       
Sbjct: 775  NVQVYNP--TPNSLDVRWDPAPGPVLQYRVVYS-----PVDGTRPSESIVVPGNTRMVHL 827

Query: 1143 --LTPGVEY-VYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERST 1199
              L P   Y V  + +  DG+   +P   + + P S P NL +     T  L+V+W+ + 
Sbjct: 828  ERLIPDTLYSVNLVALYSDGEGNPSPAQGRTL-PRSGPRNLRV-FGETTNSLSVAWDHAD 885

Query: 1200 TPDITGYRITTTPTNGQQGNSLEE--VVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESV 1257
             P +  YRI  +PT    G+ ++E   V   +++     L P   Y ++V  V +D +  
Sbjct: 886  GP-VQQYRIIYSPT---VGDPIDEYTTVPGRRNNVILQPLQPDTPYKITVIAVYEDGDGG 941

Query: 1258 PIS-DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSI 1316
             ++ +     + PP ++  ++      RV+W P PS  +  + + Y PV + E +   + 
Sbjct: 942  HLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPS-PVLGYKIVYKPVGSNEPME--AF 998

Query: 1317 SPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTV 1376
                 +  L NL P T Y V+V + Y+   S PL  +  T   + T +    I  ++F V
Sbjct: 999  VGEMTSYTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQGTTLYLNVTDLKTYQIGWDTFCV 1058

Query: 1377 HWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREE 1436
             W +P    T YR++  P     R +E  V  S  S   T L+P T+Y V++       E
Sbjct: 1059 KW-SPHRAATSYRLKLSPAD-GTRGQEITVRGSETSHCFTGLSPDTDYGVTVFVQTPNLE 1116

Query: 1437 SP-LLIGQQSTVSDVPRDLEVVAATP 1461
             P + + + +TV   P +      TP
Sbjct: 1117 GPGVSVKEHTTVK--PTEAPTEPPTP 1140



 Score =  155 bits (391), Expect = 6e-37
 Identities = 153/655 (23%), Positives = 255/655 (38%), Gaps = 48/655 (7%)

Query: 636  SHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRF 695
            S +S Y + W P  S  +  E  + G  N+   + L P  +YE   +SI      E    
Sbjct: 516  SDVSLYRITWAPFGSSDKM-ETILNGDENTLVFENLNPNTIYE---VSITAIYPDESESD 571

Query: 696  DFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYE 755
            D   +  + P+        TT        +  V   T++S  V W  AS  V  +R+ Y+
Sbjct: 572  DLIGSERTLPIL-------TTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQ 624

Query: 756  LSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPP 815
             S      Q   +     SV +  L P   Y + V  +  DGE   +    +T   +   
Sbjct: 625  PSTGEGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVR 684

Query: 816  DPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQ 875
            +  V     +++ VRW   +     Y++ Y+P+  G    + +P   N   L +LQP   
Sbjct: 685  NLRVYDPSTSTLNVRWDHAEGNPRQYKLFYAPAAGGPEELVPIPGNTNYAILRNLQPDTS 744

Query: 876  YNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVT 935
            Y +T+  V    +         T+ T R+      R++Q    T   + + W P    V 
Sbjct: 745  YTVTVVPVYTEGDG------GRTSDTGRTLMRGLARNVQVYNPTPNSLDVRWDPAPGPVL 798

Query: 936  GYRVDVIPVNLPGEHGQRLPISRNT-FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQ-Q 993
             YRV   PV+      + + +  NT    +  L P   Y   + A+    E  P  AQ +
Sbjct: 799  QYRVVYSPVD-GTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGR 857

Query: 994  TTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPS-VSKYP 1052
            T     P NL+   ET +++ V W      +  YR+    T      +Y   P   +   
Sbjct: 858  TLPRSGPRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVPGRRNNVI 917

Query: 1053 LRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTE---TTIVITW-- 1107
            L+ LQP + Y ++++A+  + +    TG   T+     +PP N  +++   T   ++W  
Sbjct: 918  LQPLQPDTPYKITVIAVYEDGDGGHLTGNGRTV---GLLPPQNIHISDEWYTRFRVSWDP 974

Query: 1108 TPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIV 1167
            +P+P +G+K+  +P    E       +  S  +  L P   Y   +    D      P+ 
Sbjct: 975  SPSPVLGYKIVYKPVGSNEPMEAFVGEMTSYTLHNLNPSTTYDVNVYAQYD-SGLSVPLT 1033

Query: 1168 NKVVTPLSPPTNLH-LEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVH 1226
            ++  T     T+L   +   DT    V W  S     T YR+  +P +G +G   E  V 
Sbjct: 1034 DQGTTLYLNVTDLKTYQIGWDT--FCVKW--SPHRAATSYRLKLSPADGTRGQ--EITVR 1087

Query: 1227 ADQSSCTFDNLSPGLEYNVSVY-----------TVKDDKESVPISDTIIPAVPPP 1270
              ++S  F  LSP  +Y V+V+           +VK+     P      P  PPP
Sbjct: 1088 GSETSHCFTGLSPDTDYGVTVFVQTPNLEGPGVSVKEHTTVKPTEAPTEPPTPPP 1142


>gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]
          Length = 2944

 Score =  235 bits (599), Expect = 4e-61
 Identities = 229/852 (26%), Positives = 364/852 (42%), Gaps = 59/852 (6%)

Query: 902  PRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVN-----LPGEHGQRLPI 956
            P  D+  +PRDL   E +   + + WT     VTGY+V   P+      LP E  +    
Sbjct: 227  PPDDSTSAPRDLVLSEPSSQSLRVQWTAASGPVTGYKVQYTPLTGLGQPLPSERQEVNVP 286

Query: 957  SRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQ-QTTKLDAPTNLQFVNETDSTVLV 1015
            +  T   + GL P   Y   V A+      + ++   +TT L+ P  L   N T  ++LV
Sbjct: 287  AGETSVRLRGLRPLTEYQVTVIALYANSIGEAVSGTARTTALEGP-ELTIQNTTAHSLLV 345

Query: 1016 RW-TPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQE 1074
             W + P A  TGYR+T  +   G  +Q  +GP      LR+L+P ++Y V++  + G   
Sbjct: 346  AWRSVPGA--TGYRVTWRVLSGGPTQQQELGPGQGSVLLRDLEPGTDYEVTVSTLFGRSV 403

Query: 1075 SPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRI-GFKLGVRPSQGGEAPREVT- 1132
             P AT +                +  T+I+++W   P   G++L  R   G E P++V  
Sbjct: 404  GP-ATSLMARTDASVEQTLRPVILGPTSILLSWNLVPEARGYRLEWRRETGLEPPQKVVL 462

Query: 1133 -SDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAP---IVNKVVTPLSPPTNLHLEANPDT 1188
             SD     + GL PG EY  T+  L +G E   P   +      P+SP T+L     P  
Sbjct: 463  PSDVTRYQLDGLQPGTEYRLTLYTLLEGHEVATPATVVPTGPELPVSPVTDLQATELPGQ 522

Query: 1189 GVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVY 1248
             V  VSW  S  P  T YRI    T G +      V+   Q++   D++  GL Y V V 
Sbjct: 523  RV-RVSW--SPVPGATQYRIIVRSTQGVERTL---VLPGSQTAFDLDDVQAGLSYTVRVS 576

Query: 1249 TVKDDKESVPISDTIIPAVPPPT---DLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPV 1305
                 +E      T+      P     LR        +RV W P P    + F + +S  
Sbjct: 577  ARVGPREGSASVLTVRREPETPLAVPGLRVVVSDATRVRVAWGPVPGA--SGFRISWSTG 634

Query: 1306 KNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTG-I 1364
               E  +  ++ P   A  +T L PGT Y V+VS +  + E        +T    P   +
Sbjct: 635  SGPE--SSQTLPPDSTATDITGLQPGTTYQVAVSVLRGREEGPAAVIVARTDPLGPVRTV 692

Query: 1365 DFSDITANSFTVHWI-APRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTE 1423
              +  +++S T+ W   P AT  GYR+  H  H  G  +   V        L  L P TE
Sbjct: 693  HVTQASSSSVTITWTRVPGAT--GYRVSWHSAH--GPEKSQLVSGEATVAELDGLEPDTE 748

Query: 1424 YVVSIVA----LNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYR 1479
            Y V + A    ++G   S ++      V  V R L+++ A+   L I+W         YR
Sbjct: 749  YTVHVRAHVAGVDGPPASVVVRTAPEPVGRVSR-LQILNASSDVLRITW-VGVTGATAYR 806

Query: 1480 ITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYR 1539
            + +G + G  P++   +PG+  +A I GL+ GV Y++ V A+ G  +      P+SI   
Sbjct: 807  LAWGRSEGG-PMRHQILPGNTDSAEIRGLEGGVSYSVRVTALVGDREGT----PVSIVVT 861

Query: 1540 TEIDKP---SQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTE 1596
            T  + P     + V    ++S+ ++W P      G+ +   P+ G    +++  GP+ + 
Sbjct: 862  TPPEAPPALGTLHVVQRGEHSLRLRWEPVPR-AQGFLLHWQPEGGQ--EQSRVLGPELSS 918

Query: 1597 MTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKG--LAFTDVDVDSIKIAWES 1654
              ++GL+P  +Y V +    P+GE      TA T   R     L   D  +DS+ +AW +
Sbjct: 919  YHLDGLEPATQYRVRLSVLGPAGEGPSAEVTARTESPRVPSIELRVVDTSIDSVTLAW-T 977

Query: 1655 PQGQVSRYRVTYSSPEDGIHELFPAPD---GEEDTAELQGLRPGSEYTVSVVALHDDMES 1711
            P  + S Y +++        E+  +P    G   +  + GL PG  Y  S+  + D +  
Sbjct: 978  PVSRASSYILSWRPLRGPGQEVPGSPQTLPGISSSQRVTGLEPGVSYIFSLTPVLDGVRG 1037

Query: 1712 QPLIGTQSTAIP 1723
                 TQ+   P
Sbjct: 1038 PEASVTQTPVCP 1049



 Score =  209 bits (532), Expect = 3e-53
 Identities = 211/875 (24%), Positives = 363/875 (41%), Gaps = 91/875 (10%)

Query: 1257 VPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKN-----EEDV 1311
            VP++     +   P DL  +     ++RV W    S  +T + V+Y+P+         + 
Sbjct: 222  VPVTRPPDDSTSAPRDLVLSEPSSQSLRVQWTAA-SGPVTGYKVQYTPLTGLGQPLPSER 280

Query: 1312 AELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITA 1371
             E+++   + +V L  L P TEY V+V ++Y       + G  +T       +   + TA
Sbjct: 281  QEVNVPAGETSVRLRGLRPLTEYQVTVIALYANSIGEAVSGTARTTALEGPELTIQNTTA 340

Query: 1372 NSFTVHWIAPRATITGYRIRHHPEHFSGRP-REDRVPHSRNSITLTNLTPGTEYVVSIVA 1430
            +S  V W +     TGYR+       SG P ++  +   + S+ L +L PGT+Y V++  
Sbjct: 341  HSLLVAWRSVPGA-TGYRVTWRV--LSGGPTQQQELGPGQGSVLLRDLEPGTDYEVTVST 397

Query: 1431 LNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSP 1490
            L GR   P       T + V + L  V   PTS+L+SW+      R YR+ +    G  P
Sbjct: 398  LFGRSVGPATSLMARTDASVEQTLRPVILGPTSILLSWNL-VPEARGYRLEWRRETGLEP 456

Query: 1491 VQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQV 1550
             Q+  +P   +   + GL+PG +Y +T+Y +    +    +  +       +   + +Q 
Sbjct: 457  PQKVVLPSDVTRYQLDGLQPGTEYRLTLYTLLEGHEVATPATVVPTGPELPVSPVTDLQA 516

Query: 1551 TDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVV 1610
            T++    + V W P     T YR+    ++  G  +T      QT   ++ +Q  + Y V
Sbjct: 517  TELPGQRVRVSWSPVPG-ATQYRIIV--RSTQGVERTLVLPGSQTAFDLDDVQAGLSYTV 573

Query: 1611 SVYAQNPSGESQPLVQTAVTNIDRP---KGLAFTDVDVDSIKIAWESPQGQVSRYRVTYS 1667
             V A+    E    V T     + P    GL     D   +++AW  P    S +R+++S
Sbjct: 574  RVSARVGPREGSASVLTVRREPETPLAVPGLRVVVSDATRVRVAW-GPVPGASGFRISWS 632

Query: 1668 SPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPT- 1726
            +           PD      ++ GL+PG+ Y V+V  L    E    +    T    P  
Sbjct: 633  TGSGPESSQTLPPD--STATDITGLQPGTTYQVAVSVLRGREEGPAAVIVARTDPLGPVR 690

Query: 1727 DLKFTQVTPTSLSAQWT-PPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVA 1785
             +  TQ + +S++  WT  P    TGY  RV+     GP K   ++ +++   + GL   
Sbjct: 691  TVHVTQASSSSVTITWTRVPGA--TGY--RVSWHSAHGPEKSQLVSGEATVAELDGLEPD 746

Query: 1786 TKYEVSVYALKDTLTSRPAQGVVTTL-ENVSPPRRARVTDATETTITISWRTKTETITGF 1844
            T+Y V V A    +   PA  VV T  E V    R ++ +A+   + I+W   T   T +
Sbjct: 747  TEYTVHVRAHVAGVDGPPASVVVRTAPEPVGRVSRLQILNASSDVLRITWVGVTGA-TAY 805

Query: 1845 QVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAID 1904
            ++    + G     + +  +  S  I GL+ G  Y + +  L  +   +PV I  +T  +
Sbjct: 806  RLAWGRSEGGPMRHQILPGNTDSAEIRGLEGGVSYSVRVTALVGDREGTPVSIVVTTPPE 865

Query: 1905 AP---SNLRFLATTPNSLLVSWQP-PRARITGYIIKYEKPGSPPREVVPRPRPGVTEATI 1960
            AP     L  +    +SL + W+P PRA+  G+++ ++  G   +  V  P   ++   +
Sbjct: 866  APPALGTLHVVQRGEHSLRLRWEPVPRAQ--GFLLHWQPEGGQEQSRVLGPE--LSSYHL 921

Query: 1961 TGLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQKTPFVTHPGYDTGNGIQLPGTSGQQPS 2020
             GLEP T+Y + +  L                                    G +G+ PS
Sbjct: 922  DGLEPATQYRVRLSVL------------------------------------GPAGEGPS 945

Query: 2021 VGQQMIFEEHGFRRTTPPTTATPIRHRPRPYPPNVGQEALSQTTISWAPFQDTSEYIISC 2080
                    E   R  +P   +  +R         V   ++   T++W P    S YI+S 
Sbjct: 946  A-------EVTARTESPRVPSIELR---------VVDTSIDSVTLAWTPVSRASSYILSW 989

Query: 2081 HPV---GTDEEPLQFRVPGTSTSATLTGLTRGATY 2112
             P+   G +       +PG S+S  +TGL  G +Y
Sbjct: 990  RPLRGPGQEVPGSPQTLPGISSSQRVTGLEPGVSY 1024



 Score =  205 bits (522), Expect = 4e-52
 Identities = 224/853 (26%), Positives = 355/853 (41%), Gaps = 50/853 (5%)

Query: 1165 PIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSL--- 1221
            P+        S P +L L + P +  L V W  ++ P +TGY++  TP  G  G  L   
Sbjct: 223  PVTRPPDDSTSAPRDLVL-SEPSSQSLRVQWTAASGP-VTGYKVQYTPLTGL-GQPLPSE 279

Query: 1222 --EEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRFTNIG 1279
              E  V A ++S     L P  EY V+V  +  +     +S T         +L   N  
Sbjct: 280  RQEVNVPAGETSVRLRGLRPLTEYQVTVIALYANSIGEAVSGTARTTALEGPELTIQNTT 339

Query: 1280 PDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVS 1339
              ++ V W   P    T + V +  V +     +  + P   +V+L +L PGT+Y V+VS
Sbjct: 340  AHSLLVAWRSVPGA--TGYRVTWR-VLSGGPTQQQELGPGQGSVLLRDLEPGTDYEVTVS 396

Query: 1340 SVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHW-IAPRATITGYRIRHHPEHFS 1398
            +++ +          +T       +    +   S  + W + P A   GYR+    E   
Sbjct: 397  TLFGRSVGPATSLMARTDASVEQTLRPVILGPTSILLSWNLVPEAR--GYRLEWRRETGL 454

Query: 1399 GRPREDRVPHSRNSITLTNLTPGTEYVVSIVAL-NGRE-ESPLLI---GQQSTVSDVPRD 1453
              P++  +P       L  L PGTEY +++  L  G E  +P  +   G +  VS V  D
Sbjct: 455  EPPQKVVLPSDVTRYQLDGLQPGTEYRLTLYTLLEGHEVATPATVVPTGPELPVSPVT-D 513

Query: 1454 LEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVD 1513
            L+        + +SW +P      YRI    T G    +   +PGS++   +  ++ G+ 
Sbjct: 514  LQATELPGQRVRVSW-SPVPGATQYRIIVRSTQGVE--RTLVLPGSQTAFDLDDVQAGLS 570

Query: 1514 YTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYR 1573
            YT+ V A  G  +  AS   +     T +  P  ++V       + V W P     +G+R
Sbjct: 571  YTVRVSARVGPREGSASVLTVRREPETPLAVPG-LRVVVSDATRVRVAWGPVPG-ASGFR 628

Query: 1574 VTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNID 1633
            ++ +   G GP  ++T  PD T   I GLQP   Y V+V       E    V  A T+  
Sbjct: 629  ISWS--TGSGPESSQTLPPDSTATDITGLQPGTTYQVAVSVLRGREEGPAAVIVARTDPL 686

Query: 1634 RP-KGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGL 1692
             P + +  T     S+ I W    G    YRV++ S      E      GE   AEL GL
Sbjct: 687  GPVRTVHVTQASSSSVTITWTRVPGATG-YRVSWHSAHGP--EKSQLVSGEATVAELDGL 743

Query: 1693 RPGSEYTVSV---VALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQL 1749
             P +EYTV V   VA  D   +  ++ T    +   + L+    +   L   W       
Sbjct: 744  EPDTEYTVHVRAHVAGVDGPPASVVVRTAPEPVGRVSRLQILNASSDVLRITWVGVT-GA 802

Query: 1750 TGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVT 1809
            T YR+    + + GPM+   L  ++ S  + GL     Y V V AL       P   VVT
Sbjct: 803  TAYRL-AWGRSEGGPMRHQILPGNTDSAEIRGLEGGVSYSVRVTALVGDREGTPVSIVVT 861

Query: 1810 TLENVSPPRRA-RVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSY 1868
            T     P      V    E ++ + W        GF +   P  GQ    R + P++ SY
Sbjct: 862  TPPEAPPALGTLHVVQRGEHSLRLRWEPVPRA-QGFLLHWQPEGGQEQ-SRVLGPELSSY 919

Query: 1869 TITGLQPGTDYKIYLYTLNDNARSSPVVIDAST-AIDAPS-NLRFLATTPNSLLVSWQPP 1926
             + GL+P T Y++ L  L          + A T +   PS  LR + T+ +S+ ++W P 
Sbjct: 920  HLDGLEPATQYRVRLSVLGPAGEGPSAEVTARTESPRVPSIELRVVDTSIDSVTLAWTPV 979

Query: 1927 RARITGYIIKYEKPGSPPREV--VPRPRPGVTEA-TITGLEPGTEYTIYVIALKNNQKSE 1983
             +R + YI+ +     P +EV   P+  PG++ +  +TGLEPG  Y   +  + +  +  
Sbjct: 980  -SRASSYILSWRPLRGPGQEVPGSPQTLPGISSSQRVTGLEPGVSYIFSLTPVLDGVR-- 1036

Query: 1984 PLIGRKKTVQKTP 1996
               G + +V +TP
Sbjct: 1037 ---GPEASVTQTP 1046



 Score =  200 bits (508), Expect = 2e-50
 Identities = 217/826 (26%), Positives = 348/826 (42%), Gaps = 60/826 (7%)

Query: 1096 TEVTETTIVITWTPA--PRIGFKLGVRPSQGGEAP-----REVTSDSG--SIVVSGLTPG 1146
            +E +  ++ + WT A  P  G+K+   P  G   P     +EV   +G  S+ + GL P 
Sbjct: 241  SEPSSQSLRVQWTAASGPVTGYKVQYTPLTGLGQPLPSERQEVNVPAGETSVRLRGLRPL 300

Query: 1147 VEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGY 1206
             EY  T+  L      +A       T L  P  L ++ N     L V+W   + P  TGY
Sbjct: 301  TEYQVTVIALYANSIGEAVSGTARTTALEGP-ELTIQ-NTTAHSLLVAWR--SVPGATGY 356

Query: 1207 RITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPA 1266
            R+T    +G  G + ++ +   Q S    +L PG +Y V+V T+         S      
Sbjct: 357  RVTWRVLSG--GPTQQQELGPGQGSVLLRDLEPGTDYEVTVSTLFGRSVGPATSLMARTD 414

Query: 1267 VPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLT 1326
                  LR   +GP ++ ++W   P  +   + + +      E   ++ +        L 
Sbjct: 415  ASVEQTLRPVILGPTSILLSWNLVP--EARGYRLEWRRETGLEPPQKVVLPSDVTRYQLD 472

Query: 1327 NLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSP----TGIDFSDITANSFTVHWIAPR 1382
             L PGTEY +++ ++ E HE         TG + P    T +  +++      V W +P 
Sbjct: 473  GLQPGTEYRLTLYTLLEGHEVATPATVVPTGPELPVSPVTDLQATELPGQRVRVSW-SPV 531

Query: 1383 ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREE---SPL 1439
               T YRI        G  R   +P S+ +  L ++  G  Y V + A  G  E   S L
Sbjct: 532  PGATQYRIIVRSTQ--GVERTLVLPGSQTAFDLDDVQAGLSYTVRVSARVGPREGSASVL 589

Query: 1440 LIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGS 1499
             + ++         L VV +  T + ++W  P      +RI++    G+ P    T+P  
Sbjct: 590  TVRREPETPLAVPGLRVVVSDATRVRVAW-GPVPGASGFRISWST--GSGPESSQTLPPD 646

Query: 1500 KSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQ-MQVTDVQDNSI 1558
             +   I+GL+PG  Y + V  + GR + PA+     I  RT+   P + + VT    +S+
Sbjct: 647  STATDITGLQPGTTYQVAVSVLRGREEGPAAV----IVARTDPLGPVRTVHVTQASSSSV 702

Query: 1559 SVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPS 1618
            ++ W       TGYRV+    +  GP K++    + T   ++GL+P  EY V V A    
Sbjct: 703  TITWTRVPG-ATGYRVSW--HSAHGPEKSQLVSGEATVAELDGLEPDTEYTVHVRAHVAG 759

Query: 1619 GESQP---LVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGI-- 1673
             +  P   +V+TA   + R   L   +   D ++I W    G  + YR+ +   E G   
Sbjct: 760  VDGPPASVVVRTAPEPVGRVSRLQILNASSDVLRITWVGVTGATA-YRLAWGRSEGGPMR 818

Query: 1674 HELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPL---IGTQSTAIPAPTDLKF 1730
            H++ P   G  D+AE++GL  G  Y+V V AL  D E  P+   + T   A PA   L  
Sbjct: 819  HQILP---GNTDSAEIRGLEGGVSYSVRVTALVGDREGTPVSIVVTTPPEAPPALGTLHV 875

Query: 1731 TQVTPTSLSAQWTP-PNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYE 1789
             Q    SL  +W P P  Q  G+ +   P+   G  +   L P+ SS  + GL  AT+Y 
Sbjct: 876  VQRGEHSLRLRWEPVPRAQ--GFLLHWQPEG--GQEQSRVLGPELSSYHLDGLEPATQYR 931

Query: 1790 VSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAV 1849
            V +  L        A+    T     P    RV D +  ++T++W T     + + +   
Sbjct: 932  VRLSVLGPAGEGPSAEVTARTESPRVPSIELRVVDTSIDSVTLAW-TPVSRASSYILSWR 990

Query: 1850 PANG---QTPIQRTIKPDV-RSYTITGLQPGTDYKIYLYTLNDNAR 1891
            P  G   + P      P +  S  +TGL+PG  Y   L  + D  R
Sbjct: 991  PLRGPGQEVPGSPQTLPGISSSQRVTGLEPGVSYIFSLTPVLDGVR 1036



 Score =  194 bits (494), Expect = 6e-49
 Identities = 220/875 (25%), Positives = 369/875 (42%), Gaps = 72/875 (8%)

Query: 696  DFTTTSTSTPVTSN----TVTGETTPFSPLVATSES----VTEITASSFVVSWVSASDTV 747
            DF+   T  P+ S     T  G      P  +TS      ++E ++ S  V W +AS  V
Sbjct: 200  DFSILRTLLPLVSRRVCTTAGGVPVTRPPDDSTSAPRDLVLSEPSSQSLRVQWTAASGPV 259

Query: 748  SGFRVEYE-LSEEGD----EPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLI 802
            +G++V+Y  L+  G     E Q +++P+  TSV +  L P  +Y V V  +  +     +
Sbjct: 260  TGYKVQYTPLTGLGQPLPSERQEVNVPAGETSVRLRGLRPLTEYQVTVIALYANSIGEAV 319

Query: 803  LSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETA 862
              T++TTA + P + T+      S++V W R     TGYR+ +     G + +  L    
Sbjct: 320  SGTARTTALEGP-ELTIQNTTAHSLLVAW-RSVPGATGYRVTWRVLSGGPTQQQELGPGQ 377

Query: 863  NSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVK 922
             SV L DL+PG  Y +T+  +          +   T  +      P       V +    
Sbjct: 378  GSVLLRDLEPGTDYEVTVSTLFGRSVGPATSLMARTDASVEQTLRP-------VILGPTS 430

Query: 923  VTIMWTPPESAVTGYRVDVI-PVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVS 981
            + + W     A  GYR++      L       LP S  T  ++ GL PG  Y   ++ + 
Sbjct: 431  ILLSWNLVPEA-RGYRLEWRRETGLEPPQKVVLP-SDVTRYQLDGLQPGTEYRLTLYTLL 488

Query: 982  HGRE-SKPLTAQQT---TKLDAPTNLQFVNETDSTVLVRWTP-PRAQITGYRLTVGLTRR 1036
             G E + P T   T     +   T+LQ        V V W+P P A  T YR+ V  T+ 
Sbjct: 489  EGHEVATPATVVPTGPELPVSPVTDLQATELPGQRVRVSWSPVPGA--TQYRIIVRSTQ- 545

Query: 1037 GQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGS--SIPPY 1094
            G  R   +  S + + L ++Q    YTV + A  G +E   A+ +    +P +  ++P  
Sbjct: 546  GVERTLVLPGSQTAFDLDDVQAGLSYTVRVSARVGPREG-SASVLTVRREPETPLAVPGL 604

Query: 1095 NTEVTETTIV-ITWTPAPRI-GFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYT 1152
               V++ T V + W P P   GF++      G E+ + +  DS +  ++GL PG  Y   
Sbjct: 605  RVVVSDATRVRVAWGPVPGASGFRISWSTGSGPESSQTLPPDSTATDITGLQPGTTYQVA 664

Query: 1153 IQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTP 1212
            + VLR  +E  A ++     PL P   +H+     + V T++W R   P  TGYR++   
Sbjct: 665  VSVLRGREEGPAAVIVARTDPLGPVRTVHVTQASSSSV-TITWTR--VPGATGYRVSWHS 721

Query: 1213 TNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPP-- 1270
             +G + + L   V  + +    D L P  EY V V       +  P S  ++   P P  
Sbjct: 722  AHGPEKSQL---VSGEATVAELDGLEPDTEYTVHVRAHVAGVDGPPAS-VVVRTAPEPVG 777

Query: 1271 --TDLRFTNIGPDTMRVTWAPPPSIDLTNFLV-RYSPVKNEEDVAELSISPSD-NAVVLT 1326
              + L+  N   D +R+TW     + +T     R +  ++E       I P + ++  + 
Sbjct: 778  RVSRLQILNASSDVLRITW-----VGVTGATAYRLAWGRSEGGPMRHQILPGNTDSAEIR 832

Query: 1327 NLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDIT---ANSFTVHWIAPRA 1383
             L  G  Y V V+++    E TP+     T  ++P  +    +     +S  + W  P  
Sbjct: 833  GLEGGVSYSVRVTALVGDREGTPVSIVVTTPPEAPPALGTLHVVQRGEHSLRLRW-EPVP 891

Query: 1384 TITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQ 1443
               G+ +   PE   G+ +   +    +S  L  L P T+Y V +  L    E P    +
Sbjct: 892  RAQGFLLHWQPE--GGQEQSRVLGPELSSYHLDGLEPATQYRVRLSVLGPAGEGP--SAE 947

Query: 1444 QSTVSDVPR----DLEVVAATPTSLLISWDAPAVTVRYYRITYGE---TGGNSPVQEFTV 1496
             +  ++ PR    +L VV  +  S+ ++W  P      Y +++      G   P    T+
Sbjct: 948  VTARTESPRVPSIELRVVDTSIDSVTLAW-TPVSRASSYILSWRPLRGPGQEVPGSPQTL 1006

Query: 1497 PGSKSTATISGLKPGVDYTITVYAVTGRGDSPASS 1531
            PG  S+  ++GL+PGV Y  ++  V      P +S
Sbjct: 1007 PGISSSQRVTGLEPGVSYIFSLTPVLDGVRGPEAS 1041



 Score =  180 bits (457), Expect = 1e-44
 Identities = 220/885 (24%), Positives = 367/885 (41%), Gaps = 86/885 (9%)

Query: 607  SSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGR-----WKEATIPG 661
            S+S P ++ ++E  SQ  S  +QW A     ++ Y +++ P   +G+      +E  +P 
Sbjct: 231  STSAPRDLVLSEPSSQ--SLRVQWTAAS-GPVTGYKVQYTPLTGLGQPLPSERQEVNVPA 287

Query: 662  HLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPL 721
               S  ++GL+P   Y+  +I++      E       TT+   P                
Sbjct: 288  GETSVRLRGLRPLTEYQVTVIALYANSIGEAVSGTARTTALEGP---------------- 331

Query: 722  VATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLL 781
                 ++   TA S +V+W S     +G+RV + +   G   Q  +L     SV + DL 
Sbjct: 332  ---ELTIQNTTAHSLLVAWRSVPG-ATGYRVTWRVL-SGGPTQQQELGPGQGSVLLRDLE 386

Query: 782  PGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQV--DDTSIVVRWSR-PQAPI 838
            PG  Y V V  +     +S+  +TS     DA  + T+  V    TSI++ W+  P+A  
Sbjct: 387  PGTDYEVTVSTLF---GRSVGPATSLMARTDASVEQTLRPVILGPTSILLSWNLVPEA-- 441

Query: 839  TGYRIVYSPSVE-GSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQE-STPVVIQQ 896
             GYR+ +          ++ LP       L  LQPG +Y +T+Y + E  E +TP  +  
Sbjct: 442  RGYRLEWRRETGLEPPQKVVLPSDVTRYQLDGLQPGTEYRLTLYTLLEGHEVATPATVVP 501

Query: 897  ETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPI 956
                 P S       DLQ  E+   +V + W+P   A T YR+ ++      E    LP 
Sbjct: 502  TGPELPVSPVT----DLQATELPGQRVRVSWSPVPGA-TQYRI-IVRSTQGVERTLVLPG 555

Query: 957  SRNTFAEVTGLSPGVTYYFKVFAVSHGRESK----PLTAQQTTKLDAPTNLQFVNETDST 1012
            S+  F ++  +  G++Y  +V A    RE       +  +  T L  P  L+ V    + 
Sbjct: 556  SQTAF-DLDDVQAGLSYTVRVSARVGPREGSASVLTVRREPETPLAVP-GLRVVVSDATR 613

Query: 1013 VLVRWTP-PRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKG 1071
            V V W P P A  +G+R++   T  G      + P  +   +  LQP + Y V++  ++G
Sbjct: 614  VRVAWGPVPGA--SGFRISWS-TGSGPESSQTLPPDSTATDITGLQPGTTYQVAVSVLRG 670

Query: 1072 NQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAP-RIGFKLGVRPSQGGEAPRE 1130
             +E P A  V  T   G     + T+ + +++ ITWT  P   G+++    + G E  + 
Sbjct: 671  REEGPAAVIVARTDPLGPVRTVHVTQASSSSVTITWTRVPGATGYRVSWHSAHGPEKSQL 730

Query: 1131 VTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAP----IVNKVVTPLSPPTNLHLEANP 1186
            V+ ++    + GL P  E  YT+ V       D P    +V     P+   + L +  N 
Sbjct: 731  VSGEATVAELDGLEPDTE--YTVHVRAHVAGVDGPPASVVVRTAPEPVGRVSRLQI-LNA 787

Query: 1187 DTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVS 1246
             + VL ++W   T    T YR+    + G  G    +++  +  S     L  G+ Y+V 
Sbjct: 788  SSDVLRITWVGVT--GATAYRLAWGRSEG--GPMRHQILPGNTDSAEIRGLEGGVSYSVR 843

Query: 1247 VYTVKDDKESVPISDTII--PAVPPPT-DLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYS 1303
            V  +  D+E  P+S  +   P  PP    L     G  ++R+ W P P      FL+ + 
Sbjct: 844  VTALVGDREGTPVSIVVTTPPEAPPALGTLHVVQRGEHSLRLRWEPVPRAQ--GFLLHWQ 901

Query: 1304 PVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTG 1363
            P   +E    L   P  ++  L  L P T+Y V +S +    E        +T       
Sbjct: 902  PEGGQEQSRVL--GPELSSYHLDGLEPATQYRVRLSVLGPAGEGPSAEVTARTESPRVPS 959

Query: 1364 IDFS--DITANSFTVHWIAPRATITGYRIRHHP-----EHFSGRPREDRVPHSRNSITLT 1416
            I+    D + +S T+ W  P +  + Y +   P     +   G P+   +P   +S  +T
Sbjct: 960  IELRVVDTSIDSVTLAW-TPVSRASSYILSWRPLRGPGQEVPGSPQ--TLPGISSSQRVT 1016

Query: 1417 NLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATP 1461
             L PG  Y+ S+  +      P     Q+ V   PR L  V   P
Sbjct: 1017 GLEPGVSYIFSLTPVLDGVRGPEASVTQTPV--CPRGLADVVFLP 1059



 Score =  159 bits (402), Expect = 3e-38
 Identities = 181/720 (25%), Positives = 287/720 (39%), Gaps = 66/720 (9%)

Query: 562  QDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQPLQTYPSSSGPVEVFITETPS 621
            +D E GT Y++  S              +GR +G       +T  S    VE  +     
Sbjct: 383  RDLEPGTDYEVTVST------------LFGRSVGPATSLMARTDAS----VEQTLRPVIL 426

Query: 622  QPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQL 681
             P S  + WN    +    Y L WR +  +   ++  +P  +  Y + GL+PG  Y   L
Sbjct: 427  GPTSILLSWNLVPEAR--GYRLEWRRETGLEPPQKVVLPSDVTRYQLDGLQPGTEYRLTL 484

Query: 682  ISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWV 741
             ++ + GH+            +TP T    TG   P SP+  T    TE+      VSW 
Sbjct: 485  YTLLE-GHE-----------VATPATV-VPTGPELPVSPV--TDLQATELPGQRVRVSW- 528

Query: 742  SASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQI--SEDGEQ 799
            S     + +R+    S +G E + L LP + T+ ++ D+  G  Y V V       +G  
Sbjct: 529  SPVPGATQYRIIVR-STQGVE-RTLVLPGSQTAFDLDDVQAGLSYTVRVSARVGPREGSA 586

Query: 800  SLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLP 859
            S++    +   P A P   V   D T + V W  P    +G+RI +S    G  +   LP
Sbjct: 587  SVLTVRREPETPLAVPGLRVVVSDATRVRVAWG-PVPGASGFRISWSTG-SGPESSQTLP 644

Query: 860  ETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVT 919
              + +  ++ LQPG  Y + +  +   +E    VI        R+D +   R +   + +
Sbjct: 645  PDSTATDITGLQPGTTYQVAVSVLRGREEGPAAVI------VARTDPLGPVRTVHVTQAS 698

Query: 920  DVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFA 979
               VTI WT    A TGYRV     +  G    +L     T AE+ GL P   Y   V A
Sbjct: 699  SSSVTITWTRVPGA-TGYRVSWHSAH--GPEKSQLVSGEATVAELDGLEPDTEYTVHVRA 755

Query: 980  VSHGRESKPLTAQQTT---KLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRR 1036
               G +  P +    T    +   + LQ +N +   + + W       T YRL  G +  
Sbjct: 756  HVAGVDGPPASVVVRTAPEPVGRVSRLQILNASSDVLRITWVGVTG-ATAYRLAWGRSEG 814

Query: 1037 GQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNT 1096
            G  R   +  +     +R L+    Y+V + A+ G++E    + V TT  P  + P   T
Sbjct: 815  GPMRHQILPGNTDSAEIRGLEGGVSYSVRVTALVGDREGTPVSIVVTT--PPEAPPALGT 872

Query: 1097 ----EVTETTIVITWTPAPRI-GFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVY 1151
                +  E ++ + W P PR  GF L  +P  G E  R +  +  S  + GL P  +Y  
Sbjct: 873  LHVVQRGEHSLRLRWEPVPRAQGFLLHWQPEGGQEQSRVLGPELSSYHLDGLEPATQYRV 932

Query: 1152 TIQVLRD-GQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITT 1210
             + VL   G+   A +  +  +P  P   L +    DT + +V+   +     + Y ++ 
Sbjct: 933  RLSVLGPAGEGPSAEVTARTESPRVPSIELRV---VDTSIDSVTLAWTPVSRASSYILSW 989

Query: 1211 TPTN--GQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVP 1268
             P    GQ+     + +    SS     L PG+ Y  S+  V D       S T  P  P
Sbjct: 990  RPLRGPGQEVPGSPQTLPGISSSQRVTGLEPGVSYIFSLTPVLDGVRGPEASVTQTPVCP 1049



 Score =  119 bits (298), Expect = 3e-26
 Identities = 151/659 (22%), Positives = 263/659 (39%), Gaps = 82/659 (12%)

Query: 1521 VTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKN 1580
            V+ R  + A   P++         P  + +++    S+ V+W  +S PVTGY+V  TP  
Sbjct: 211  VSRRVCTTAGGVPVTRPPDDSTSAPRDLVLSEPSSQSLRVQWTAASGPVTGYKVQYTPLT 270

Query: 1581 G-----PGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRP 1635
            G     P   +       +T + + GL+P  EY V+V A   +   + +  TA T     
Sbjct: 271  GLGQPLPSERQEVNVPAGETSVRLRGLRPLTEYQVTVIALYANSIGEAVSGTARTTALEG 330

Query: 1636 KGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDG---IHELFPAPDGEEDTAELQGL 1692
              L   +    S+ +AW S  G  + YRVT+     G     EL P     + +  L+ L
Sbjct: 331  PELTIQNTTAHSLLVAWRSVPG-ATGYRVTWRVLSGGPTQQQELGPG----QGSVLLRDL 385

Query: 1693 RPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQ------VTPTSLSAQWTPPN 1746
             PG++Y V+V  L             +T++ A TD    Q      + PTS+   W    
Sbjct: 386  EPGTDYEVTVSTLFGRSVG------PATSLMARTDASVEQTLRPVILGPTSILLSWNLV- 438

Query: 1747 VQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYA-LKDTLTSRPAQ 1805
             +  GYR+    +    P +++ L  D +   + GL   T+Y +++Y  L+    + PA 
Sbjct: 439  PEARGYRLEWRRETGLEPPQKVVLPSDVTRYQLDGLQPGTEYRLTLYTLLEGHEVATPAT 498

Query: 1806 GVVTTLE-NVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRT--IK 1862
             V T  E  VSP    + T+     + +SW      + G     +       ++RT  + 
Sbjct: 499  VVPTGPELPVSPVTDLQATELPGQRVRVSW----SPVPGATQYRIIVRSTQGVERTLVLP 554

Query: 1863 PDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAP---SNLRFLATTPNSL 1919
                ++ +  +Q G  Y + +         S  V+      + P     LR + +    +
Sbjct: 555  GSQTAFDLDDVQAGLSYTVRVSARVGPREGSASVLTVRREPETPLAVPGLRVVVSDATRV 614

Query: 1920 LVSWQP-PRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKN 1978
             V+W P P A  +G+ I +   GS P      P P  T   ITGL+PGT Y + V  L+ 
Sbjct: 615  RVAWGPVPGA--SGFRISW-STGSGPESSQTLP-PDSTATDITGLQPGTTYQVAVSVLRG 670

Query: 1979 NQKSEPLIGRKKTVQKTPFVT-HPGYDTGNGI-----QLPGTSGQQPS------------ 2020
             ++    +   +T    P  T H    + + +     ++PG +G + S            
Sbjct: 671  REEGPAAVIVARTDPLGPVRTVHVTQASSSSVTITWTRVPGATGYRVSWHSAHGPEKSQL 730

Query: 2021 -VGQQMIFEEHGFRRTTP--------------PTTATPIRHRPRPYPPNVGQEALSQTT- 2064
              G+  + E  G    T               P  +  +R  P P       + L+ ++ 
Sbjct: 731  VSGEATVAELDGLEPDTEYTVHVRAHVAGVDGPPASVVVRTAPEPVGRVSRLQILNASSD 790

Query: 2065 ---ISWAPFQDTSEYIISCHPVGTDEEPLQFRV-PGTSTSATLTGLTRGATYNIIVEAL 2119
               I+W      + Y ++     ++  P++ ++ PG + SA + GL  G +Y++ V AL
Sbjct: 791  VLRITWVGVTGATAYRLAWG--RSEGGPMRHQILPGNTDSAEIRGLEGGVSYSVRVTAL 847



 Score =  111 bits (278), Expect = 7e-24
 Identities = 120/464 (25%), Positives = 195/464 (42%), Gaps = 67/464 (14%)

Query: 1713 PLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGP-----MKE 1767
            P+      +  AP DL  ++ +  SL  QWT  +  +TGY+V+ TP    G       +E
Sbjct: 223  PVTRPPDDSTSAPRDLVLSEPSSQSLRVQWTAASGPVTGYKVQYTPLTGLGQPLPSERQE 282

Query: 1768 INLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATE 1827
            +N+    +SV + GL   T+Y+V+V AL          G   T     P     + + T 
Sbjct: 283  VNVPAGETSVRLRGLRPLTEYQVTVIALYANSIGEAVSGTARTTALEGP--ELTIQNTTA 340

Query: 1828 TTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLN 1887
             ++ ++WR+     TG++V     +G    Q+ + P   S  +  L+PGTDY++ + TL 
Sbjct: 341  HSLLVAWRS-VPGATGYRVTWRVLSGGPTQQQELGPGQGSVLLRDLEPGTDYEVTVSTLF 399

Query: 1888 DNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQ-PPRARITGYIIKYEKPGS--PP 1944
              +      + A T       LR +   P S+L+SW   P AR  GY +++ +     PP
Sbjct: 400  GRSVGPATSLMARTDASVEQTLRPVILGPTSILLSWNLVPEAR--GYRLEWRRETGLEPP 457

Query: 1945 REVVPRPRPGVTEATITGLEPGTEY--TIYVIALKNNQKSEP------------------ 1984
            ++VV      VT   + GL+PGTEY  T+Y + L+ ++ + P                  
Sbjct: 458  QKVVLPS--DVTRYQLDGLQPGTEYRLTLYTL-LEGHEVATPATVVPTGPELPVSPVTDL 514

Query: 1985 ----LIGRKKTVQKTPFVTHPGYDTGNGIQLPGTSGQQPSV---GQQMIFEEHGFRRTTP 2037
                L G++  V  +P    PG  T   I +  T G + ++   G Q  F+    +    
Sbjct: 515  QATELPGQRVRVSWSPV---PGA-TQYRIIVRSTQGVERTLVLPGSQTAFDLDDVQAGLS 570

Query: 2038 PTTATPIRHRPR------------PYPP------NVGQEALSQTTISWAPFQDTSEYIIS 2079
             T     R  PR            P  P       V     ++  ++W P    S + IS
Sbjct: 571  YTVRVSARVGPREGSASVLTVRREPETPLAVPGLRVVVSDATRVRVAWGPVPGASGFRIS 630

Query: 2080 CHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQ 2123
                G+  E  Q  +P  ST+  +TGL  G TY + V  L+ ++
Sbjct: 631  WS-TGSGPESSQ-TLPPDSTATDITGLQPGTTYQVAVSVLRGRE 672


>gi|55743096 collagen, type XIV, alpha 1 [Homo sapiens]
          Length = 1796

 Score =  209 bits (531), Expect = 3e-53
 Identities = 177/706 (25%), Positives = 316/706 (44%), Gaps = 55/706 (7%)

Query: 1219 NSLEEVVHADQSS-----CTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDL 1273
            N L+E+     S+       FD +   +E        + +++   I  +      PPT+L
Sbjct: 300  NELQEIASEPDSTHVYNVAEFDLMHTVVESLTRTLCSRVEEQDREIKASAHAITGPPTEL 359

Query: 1274 RFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTE 1333
              + +   +  V W   P  ++  + V Y P +  +   E+ +  + ++ VL NL+  TE
Sbjct: 360  ITSEVTARSFMVNWTHAPG-NVEKYRVVYYPTRGGKP-DEVVVDGTVSSTVLKNLMSLTE 417

Query: 1334 YVVSVSSVYEQHESTPLRGRQKT-GLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRH 1392
            Y ++V ++Y    S  LRG + T  L   + +   D+T NS  V W A     +GY I +
Sbjct: 418  YQIAVFAIYAHTASEGLRGTETTLALPMASDLLLYDVTENSMRVKWDAVPGA-SGYLILY 476

Query: 1393 HP--EHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVS-D 1449
             P  E  +G  +E ++  +   I L+ L P TEY V++ A+ G E S  + GQ++T++  
Sbjct: 477  APLTEGLAGDEKEMKIGETHTDIELSGLLPNTEYTVTVYAMFGEEASDPVTGQETTLALS 536

Query: 1450 VPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLK 1509
             PR+L +      S  ++WD  +  +  YRI Y    G   + E  V    +T  + GL 
Sbjct: 537  PPRNLRISNVGSNSARLTWDPTSRQINGYRIVYNNADGTE-INEVEVDPI-TTFPLKGLT 594

Query: 1510 PGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQ--MQVTDVQDNSISVKWLPSSS 1567
            P  +YTI ++++   G S    +P++  + TE + P+Q  +++ +V  +S  V W P S+
Sbjct: 595  PLTEYTIAIFSIYDEGQS----EPLTGVFTTE-EVPAQQYLEIDEVTTDSFRVTWHPLSA 649

Query: 1568 PVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQT 1627
                +++   P  G G T+      +Q    IEGL+P  EY VS+ A    G    +V  
Sbjct: 650  DEGLHKLMWIPVYG-GKTEEVVLKEEQDSHVIEGLEPGTEYEVSLLAVLDDGSESEVVTA 708

Query: 1628 AVTNIDR----------------------PKGLAFTDVDVDSIKIAWESPQGQVSRYRVT 1665
              T +D                        + L   D    S+++ W+     V ++RVT
Sbjct: 709  VGTTLDSFWTEPATTIVPTTSVTSVFQTGIRNLVVGDETTSSLRVKWDISDSDVQQFRVT 768

Query: 1666 YSS----PEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTA 1721
            Y +    PE+ +      P G ++   L+ L P +EY V+V  ++ D E   +     T 
Sbjct: 769  YMTAQGDPEEEVIGTVMVP-GSQNNLLLKPLLPDTEYKVTVTPIYTDGEGVSVSAPGKT- 826

Query: 1722 IPA--PTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVV 1779
            +P+  P +L+ ++     L   W PP+  + GYR+   P    GP  E  +  D +++++
Sbjct: 827  LPSSGPQNLRVSEEWYNRLRITWDPPSSPVKGYRIVYKPVSVPGPTLETFVGADINTILI 886

Query: 1780 SGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTE 1839
            + L+    Y V ++A + +  S    G+V TL       +A+  +   T++   W+    
Sbjct: 887  TNLLSGMDYNVKIFASQASGFSDALTGMVKTLFLGVTNLQAKHVEM--TSLCAHWQVHRH 944

Query: 1840 TITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYT 1885
              T ++V       +   + T+      +   GLQP ++YKI +YT
Sbjct: 945  A-TAYRVVIESLQDRQKQESTVGGGTTRHCFYGLQPDSEYKISVYT 989



 Score =  201 bits (510), Expect = 9e-51
 Identities = 184/688 (26%), Positives = 292/688 (42%), Gaps = 53/688 (7%)

Query: 795  EDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSST 854
            E+ ++ +  S    T P  P +    +V   S +V W+     +  YR+VY P+  G   
Sbjct: 339  EEQDREIKASAHAITGP--PTELITSEVTARSFMVNWTHAPGNVEKYRVVYYPTRGGKPD 396

Query: 855  ELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQ 914
            E+ +  T +S  L +L    +Y I ++A+  +  S      +   GT  +  +P   DL 
Sbjct: 397  EVVVDGTVSSTVLKNLMSLTEYQIAVFAIYAHTAS------EGLRGTETTLALPMASDLL 450

Query: 915  FVEVTDVKVTIMWTPPESAVTGYRVDVIPV--NLPGEHGQRLPISRNTFAEVTGLSPGVT 972
              +VT+  + + W     A +GY +   P+   L G+  +      +T  E++GL P   
Sbjct: 451  LYDVTENSMRVKWDAVPGA-SGYLILYAPLTEGLAGDEKEMKIGETHTDIELSGLLPNTE 509

Query: 973  YYFKVFAVSHGRESKPLTAQQTT-KLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTV 1031
            Y   V+A+     S P+T Q+TT  L  P NL+  N   ++  + W P   QI GYR+  
Sbjct: 510  YTVTVYAMFGEEASDPVTGQETTLALSPPRNLRISNVGSNSARLTWDPTSRQINGYRIVY 569

Query: 1032 GLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSI 1091
                  +  +  V P ++ +PL+ L P +EYT+++ +I    +S   TGVFTT +  +  
Sbjct: 570  NNADGTEINEVEVDP-ITTFPLKGLTPLTEYTIAIFSIYDEGQSEPLTGVFTTEEVPAQQ 628

Query: 1092 PPYNTEVTETTIVITWTP--APRIGFKLGVRPSQGGEAPREV-TSDSGSIVVSGLTPGVE 1148
                 EVT  +  +TW P  A     KL   P  GG+    V   +  S V+ GL PG E
Sbjct: 629  YLEIDEVTTDSFRVTWHPLSADEGLHKLMWIPVYGGKTEEVVLKEEQDSHVIEGLEPGTE 688

Query: 1149 Y-VYTIQVLRDGQERDAPIV---------NKVVTPLSPPTNLH----------LEANPDT 1188
            Y V  + VL DG E +              +  T + P T++           +  +  T
Sbjct: 689  YEVSLLAVLDDGSESEVVTAVGTTLDSFWTEPATTIVPTTSVTSVFQTGIRNLVVGDETT 748

Query: 1189 GVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEV-----VHADQSSCTFDNLSPGLEY 1243
              L V W+ S + D+  +R+T       QG+  EEV     V   Q++     L P  EY
Sbjct: 749  SSLRVKWDISDS-DVQQFRVTYMTA---QGDPEEEVIGTVMVPGSQNNLLLKPLLPDTEY 804

Query: 1244 NVSVYTVKDDKESVPIS--DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVR 1301
             V+V  +  D E V +S     +P+   P +LR +    + +R+TW  PPS  +  + + 
Sbjct: 805  KVTVTPIYTDGEGVSVSAPGKTLPS-SGPQNLRVSEEWYNRLRITW-DPPSSPVKGYRIV 862

Query: 1302 YSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSP 1361
            Y PV       E  +    N +++TNLL G +Y V + +      S  L G  KT     
Sbjct: 863  YKPVSVPGPTLETFVGADINTILITNLLSGMDYNVKIFASQASGFSDALTGMVKTLFLGV 922

Query: 1362 TGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPR-EDRVPHSRNSITLTNLTP 1420
            T +    +   S   HW   R   T YR+    E    R + E  V           L P
Sbjct: 923  TNLQAKHVEMTSLCAHWQVHRHA-TAYRV--VIESLQDRQKQESTVGGGTTRHCFYGLQP 979

Query: 1421 GTEYVVSIVALNGREESPLLIGQQSTVS 1448
             +EY +S+       E P +   + T S
Sbjct: 980  DSEYKISVYTKLQEIEGPSVSIMEKTQS 1007



 Score =  190 bits (482), Expect = 2e-47
 Identities = 177/665 (26%), Positives = 292/665 (43%), Gaps = 50/665 (7%)

Query: 1096 TEVTETTIVITWTPAPRIGFKLGV--RPSQGGEAPREVTSDS--GSIVVSGLTPGVEYVY 1151
            +EVT  + ++ WT AP    K  V   P++GG+ P EV  D    S V+  L    EY  
Sbjct: 362  SEVTARSFMVNWTHAPGNVEKYRVVYYPTRGGK-PDEVVVDGTVSSTVLKNLMSLTEYQI 420

Query: 1152 TIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTT 1211
             +  +      +     +    L   ++L L    +   + V W+    P  +GY I   
Sbjct: 421  AVFAIYAHTASEGLRGTETTLALPMASDLLLYDVTENS-MRVKWD--AVPGASGYLILYA 477

Query: 1212 P-TNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS--DTIIPAVP 1268
            P T G  G+  E  +    +      L P  EY V+VY +  ++ S P++  +T + A+ 
Sbjct: 478  PLTEGLAGDEKEMKIGETHTDIELSGLLPNTEYTVTVYAMFGEEASDPVTGQETTL-ALS 536

Query: 1269 PPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNL 1328
            PP +LR +N+G ++ R+TW  P S  +  + + Y+     E + E+ + P      L  L
Sbjct: 537  PPRNLRISNVGSNSARLTW-DPTSRQINGYRIVYNNADGTE-INEVEVDPI-TTFPLKGL 593

Query: 1329 LPGTEYVVSVSSVYEQHESTPLRGRQKTG-LDSPTGIDFSDITANSFTVHWIAPRATITG 1387
             P TEY +++ S+Y++ +S PL G   T  + +   ++  ++T +SF V W    A    
Sbjct: 594  TPLTEYTIAIFSIYDEGQSEPLTGVFTTEEVPAQQYLEIDEVTTDSFRVTWHPLSADEGL 653

Query: 1388 YRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVA-LNGREESPLLIGQQST 1446
            +++   P  + G+  E  +   ++S  +  L PGTEY VS++A L+   ES ++    +T
Sbjct: 654  HKLMWIPV-YGGKTEEVVLKEEQDSHVIEGLEPGTEYEVSLLAVLDDGSESEVVTAVGTT 712

Query: 1447 VSD---------VP------------RDLEVVAATPTSLLISWDAPAVTVRYYRITYGET 1485
            +           VP            R+L V   T +SL + WD     V+ +R+TY   
Sbjct: 713  LDSFWTEPATTIVPTTSVTSVFQTGIRNLVVGDETTSSLRVKWDISDSDVQQFRVTYMTA 772

Query: 1486 GGNSPVQEFT----VPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTE 1541
             G+ P +E      VPGS++   +  L P  +Y +TV  +   G+  + S P        
Sbjct: 773  QGD-PEEEVIGTVMVPGSQNNLLLKPLLPDTEYKVTVTPIYTDGEGVSVSAP---GKTLP 828

Query: 1542 IDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEG 1601
               P  ++V++   N + + W P SSPV GYR+   P + PGPT     G D   + I  
Sbjct: 829  SSGPQNLRVSEEWYNRLRITWDPPSSPVKGYRIVYKPVSVPGPTLETFVGADINTILITN 888

Query: 1602 LQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSR 1661
            L   ++Y V ++A   SG S  L     T       L    V++ S+   W+  +   + 
Sbjct: 889  LLSGMDYNVKIFASQASGFSDALTGMVKTLFLGVTNLQAKHVEMTSLCAHWQVHR-HATA 947

Query: 1662 YRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTA 1721
            YRV   S +D   +      G        GL+P SEY +SV     ++E  P +      
Sbjct: 948  YRVVIESLQDRQKQESTVGGGTTRHC-FYGLQPDSEYKISVYTKLQEIEG-PSVSIMEKT 1005

Query: 1722 IPAPT 1726
               PT
Sbjct: 1006 QSLPT 1010



 Score =  186 bits (473), Expect = 2e-46
 Identities = 180/673 (26%), Positives = 283/673 (42%), Gaps = 53/673 (7%)

Query: 1000 PTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPA 1059
            PT L     T  + +V WT     +  YR+    TR G+P +  V  +VS   L+NL   
Sbjct: 356  PTELITSEVTARSFMVNWTHAPGNVEKYRVVYYPTRGGKPDEVVVDGTVSSTVLKNLMSL 415

Query: 1060 SEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAP-RIGFKLG 1118
            +EY +++ AI  +  S    G  TTL    +      +VTE ++ + W   P   G+ + 
Sbjct: 416  TEYQIAVFAIYAHTASEGLRGTETTLALPMASDLLLYDVTENSMRVKWDAVPGASGYLIL 475

Query: 1119 VRP----SQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVT-P 1173
              P      G E   ++      I +SGL P  EY  T+  +  G+E   P+  +  T  
Sbjct: 476  YAPLTEGLAGDEKEMKIGETHTDIELSGLLPNTEYTVTVYAM-FGEEASDPVTGQETTLA 534

Query: 1174 LSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCT 1233
            LSPP NL + +N  +    ++W+  T+  I GYRI     N   G  + EV     ++  
Sbjct: 535  LSPPRNLRI-SNVGSNSARLTWD-PTSRQINGYRIV---YNNADGTEINEVEVDPITTFP 589

Query: 1234 FDNLSPGLEYNVSVYTVKDDKESVPISDTI-IPAVPPPTDLRFTNIGPDTMRVTWAPPPS 1292
               L+P  EY ++++++ D+ +S P++       VP    L    +  D+ RVTW  P S
Sbjct: 590  LKGLTPLTEYTIAIFSIYDEGQSEPLTGVFTTEEVPAQQYLEIDEVTTDSFRVTW-HPLS 648

Query: 1293 IDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRG 1352
             D     + + PV   +   E+ +    ++ V+  L PGTEY VS+ +V +    + +  
Sbjct: 649  ADEGLHKLMWIPVYGGK-TEEVVLKEEQDSHVIEGLEPGTEYEVSLLAVLDDGSESEVVT 707

Query: 1353 RQKTGLDS-------------------PTGID---FSDITANSFTVHWIAPRATITGYRI 1390
               T LDS                    TGI      D T +S  V W    + +  +R+
Sbjct: 708  AVGTTLDSFWTEPATTIVPTTSVTSVFQTGIRNLVVGDETTSSLRVKWDISDSDVQQFRV 767

Query: 1391 RHHPEHFSGRPRED-----RVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQS 1445
             +      G P E+      VP S+N++ L  L P TEY V++  +    E   +     
Sbjct: 768  TYMTA--QGDPEEEVIGTVMVPGSQNNLLLKPLLPDTEYKVTVTPIYTDGEGVSVSAPGK 825

Query: 1446 TV-SDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTAT 1504
            T+ S  P++L V       L I+WD P+  V+ YRI Y       P  E  V    +T  
Sbjct: 826  TLPSSGPQNLRVSEEWYNRLRITWDPPSSPVKGYRIVYKPVSVPGPTLETFVGADINTIL 885

Query: 1505 ISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLP 1564
            I+ L  G+DY + ++A    G S A +  +    +T     + +Q   V+  S+   W  
Sbjct: 886  ITNLLSGMDYNVKIFASQASGFSDALTGMV----KTLFLGVTNLQAKHVEMTSLCAHW-Q 940

Query: 1565 SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYA--QNPSGESQ 1622
                 T YRV           +  T G   T     GLQP  EY +SVY   Q   G S 
Sbjct: 941  VHRHATAYRVVIESLQ-DRQKQESTVGGGTTRHCFYGLQPDSEYKISVYTKLQEIEGPSV 999

Query: 1623 PLVQTAVTNIDRP 1635
             +++   +   RP
Sbjct: 1000 SIMEKTQSLPTRP 1012



 Score =  181 bits (458), Expect = 1e-44
 Identities = 170/702 (24%), Positives = 295/702 (42%), Gaps = 72/702 (10%)

Query: 1339 SSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFS 1398
            S V EQ           TG   PT +  S++TA SF V+W      +  YR+ ++P    
Sbjct: 336  SRVEEQDREIKASAHAITG--PPTELITSEVTARSFMVNWTHAPGNVEKYRVVYYPTR-G 392

Query: 1399 GRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVS-DVPRDLEVV 1457
            G+P E  V  + +S  L NL   TEY +++ A+     S  L G ++T++  +  DL + 
Sbjct: 393  GKPDEVVVDGTVSSTVLKNLMSLTEYQIAVFAIYAHTASEGLRGTETTLALPMASDLLLY 452

Query: 1458 AATPTSLLISWDA----PAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVD 1513
              T  S+ + WDA        + Y  +T G  G     +E  +  + +   +SGL P  +
Sbjct: 453  DVTENSMRVKWDAVPGASGYLILYAPLTEGLAGDE---KEMKIGETHTDIELSGLLPNTE 509

Query: 1514 YTITVYAVTGRGDSPASSKPISINYRT-EIDKPSQMQVTDVQDNSISVKWLPSSSPVTGY 1572
            YT+TVYA+ G      +S P++    T  +  P  +++++V  NS  + W P+S  + GY
Sbjct: 510  YTVTVYAMFGE----EASDPVTGQETTLALSPPRNLRISNVGSNSARLTWDPTSRQINGY 565

Query: 1573 RVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTN- 1631
            R+     N  G    +      T   ++GL P  EY +++++    G+S+PL     T  
Sbjct: 566  RIVYN--NADGTEINEVEVDPITTFPLKGLTPLTEYTIAIFSIYDEGQSEPLTGVFTTEE 623

Query: 1632 IDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAP----------- 1680
            +   + L   +V  DS ++ W               S ++G+H+L   P           
Sbjct: 624  VPAQQYLEIDEVTTDSFRVTWHP------------LSADEGLHKLMWIPVYGGKTEEVVL 671

Query: 1681 DGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAI------PAPTDLKFTQVT 1734
              E+D+  ++GL PG+EY VS++A+ DD     ++    T +      PA T +  T VT
Sbjct: 672  KEEQDSHVIEGLEPGTEYEVSLLAVLDDGSESEVVTAVGTTLDSFWTEPATTIVPTTSVT 731

Query: 1735 P----------------TSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEIN--LAPDS-S 1775
                             +SL  +W   +  +  +RV     +     + I   + P S +
Sbjct: 732  SVFQTGIRNLVVGDETTSSLRVKWDISDSDVQQFRVTYMTAQGDPEEEVIGTVMVPGSQN 791

Query: 1776 SVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWR 1835
            ++++  L+  T+Y+V+V  +              TL + S P+  RV++     + I+W 
Sbjct: 792  NLLLKPLLPDTEYKVTVTPIYTDGEGVSVSAPGKTLPS-SGPQNLRVSEEWYNRLRITWD 850

Query: 1836 TKTETITGFQVDAVPANGQTPIQRT-IKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSP 1894
              +  + G+++   P +   P   T +  D+ +  IT L  G DY + ++    +  S  
Sbjct: 851  PPSSPVKGYRIVYKPVSVPGPTLETFVGADINTILITNLLSGMDYNVKIFASQASGFSDA 910

Query: 1895 VVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPG 1954
            +     T     +NL+       SL   WQ  R   T Y +  E      ++       G
Sbjct: 911  LTGMVKTLFLGVTNLQAKHVEMTSLCAHWQVHR-HATAYRVVIESLQDRQKQ-ESTVGGG 968

Query: 1955 VTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQKTP 1996
             T     GL+P +EY I V   K  +   P +   +  Q  P
Sbjct: 969  TTRHCFYGLQPDSEYKISVYT-KLQEIEGPSVSIMEKTQSLP 1009



 Score =  175 bits (443), Expect = 5e-43
 Identities = 231/983 (23%), Positives = 388/983 (39%), Gaps = 120/983 (12%)

Query: 907  VPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTG 966
            V  P  L++  ++   + I W  P     GY++ V P +  G+  Q    +  T A + G
Sbjct: 30   VAPPTRLRYNVISHDSIQISWKAPRGKFGGYKLLVTPTS-GGKTNQLNLQNTATKAIIQG 88

Query: 967  LSPGVTYYFKVFAVSHGRESKPLTAQ----------------------QTTKLDAPTNLQ 1004
            L P   Y  ++ A +  +ESKP   Q                        ++  +P  ++
Sbjct: 89   LMPDQNYTVQIIAYNKDKESKPAQGQFRIKDLEKRKDPKPRVKVVDRGNGSRPSSPEEVK 148

Query: 1005 FVNET----DSTVLV--RWTPPRAQ-----------ITGYRLTVGLTRRGQPRQYNVGPS 1047
            FV +T    D  +LV   W+  R             +T + +    TR G   QY+  P 
Sbjct: 149  FVCQTPAIADIVILVDGSWSIGRFNFRLVRHFLENLVTAFDVGSEKTRIGL-AQYSGDPR 207

Query: 1048 VSKY------------PLRNLQPASEYTVSLVAIK---GNQESPKA---TGV------FT 1083
            +  +             +RNL      T++ +A+     N   P+A   TGV       T
Sbjct: 208  IEWHLNAFSTKDEVIEAVRNLPYKGGNTLTGLALNYIFENSFKPEAGSRTGVSKIGILIT 267

Query: 1084 TLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGS-----I 1138
              +    I P +  + E+ + +         F +GV+ +   E  +E+ S+  S     +
Sbjct: 268  DGKSQDDIIPPSRNLRESGVEL---------FAIGVKNADVNEL-QEIASEPDSTHVYNV 317

Query: 1139 VVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERS 1198
                L   V    T  +    +E+D  I         PPT L + +        V+W  +
Sbjct: 318  AEFDLMHTVVESLTRTLCSRVEEQDREIKASAHAITGPPTEL-ITSEVTARSFMVNWTHA 376

Query: 1199 TTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVP 1258
               ++  YR+   PT G  G   E VV    SS    NL    EY ++V+ +     S  
Sbjct: 377  -PGNVEKYRVVYYPTRG--GKPDEVVVDGTVSSTVLKNLMSLTEYQIAVFAIYAHTASEG 433

Query: 1259 ISDT-IIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKN--EEDVAELS 1315
            +  T    A+P  +DL   ++  ++MRV W   P    + +L+ Y+P+      D  E+ 
Sbjct: 434  LRGTETTLALPMASDLLLYDVTENSMRVKWDAVPG--ASGYLILYAPLTEGLAGDEKEMK 491

Query: 1316 ISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKT-GLDSPTGIDFSDITANSF 1374
            I  +   + L+ LLP TEY V+V +++ +  S P+ G++ T  L  P  +  S++ +NS 
Sbjct: 492  IGETHTDIELSGLLPNTEYTVTVYAMFGEEASDPVTGQETTLALSPPRNLRISNVGSNSA 551

Query: 1375 TVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGR 1434
             + W      I GYRI ++  +  G    +       +  L  LTP TEY ++I ++   
Sbjct: 552  RLTWDPTSRQINGYRIVYN--NADGTEINEVEVDPITTFPLKGLTPLTEYTIAIFSIYDE 609

Query: 1435 EESPLLIGQQSTVSDVPRD--LEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQ 1492
             +S  L G   T  +VP    LE+   T  S  ++W   +     +++ +    G    +
Sbjct: 610  GQSEPLTG-VFTTEEVPAQQYLEIDEVTTDSFRVTWHPLSADEGLHKLMWIPVYGGK-TE 667

Query: 1493 EFTVPGSKSTATISGLKPGVDYTITVYAVTGRG-------------DSPASSKPISINYR 1539
            E  +   + +  I GL+PG +Y +++ AV   G             DS  +    +I   
Sbjct: 668  EVVLKEEQDSHVIEGLEPGTEYEVSLLAVLDDGSESEVVTAVGTTLDSFWTEPATTIVPT 727

Query: 1540 TEIDKPSQ-----MQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTK---TKTAG 1591
            T +    Q     + V D   +S+ VKW  S S V  +RVT     G    +   T    
Sbjct: 728  TSVTSVFQTGIRNLVVGDETTSSLRVKWDISDSDVQQFRVTYMTAQGDPEEEVIGTVMVP 787

Query: 1592 PDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVT-NIDRPKGLAFTDVDVDSIKI 1650
              Q  + ++ L P  EY V+V      GE   +     T     P+ L  ++   + ++I
Sbjct: 788  GSQNNLLLKPLLPDTEYKVTVTPIYTDGEGVSVSAPGKTLPSSGPQNLRVSEEWYNRLRI 847

Query: 1651 AWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDME 1710
             W+ P   V  YR+ Y         L      + +T  +  L  G +Y V + A      
Sbjct: 848  TWDPPSSPVKGYRIVYKPVSVPGPTLETFVGADINTILITNLLSGMDYNVKIFASQASGF 907

Query: 1711 SQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINL 1770
            S  L G   T     T+L+   V  TSL A W   +   T YRV V    +    +E  +
Sbjct: 908  SDALTGMVKTLFLGVTNLQAKHVEMTSLCAHW-QVHRHATAYRV-VIESLQDRQKQESTV 965

Query: 1771 APDSSSVVVSGLMVATKYEVSVY 1793
               ++     GL   ++Y++SVY
Sbjct: 966  GGGTTRHCFYGLQPDSEYKISVY 988



 Score =  160 bits (404), Expect = 2e-38
 Identities = 156/663 (23%), Positives = 281/663 (42%), Gaps = 54/663 (8%)

Query: 729  TEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIV 788
            +E+TA SF+V+W  A   V  +RV Y     G +P  + +  T +S  + +L+   +Y +
Sbjct: 362  SEVTARSFMVNWTHAPGNVEKYRVVY-YPTRGGKPDEVVVDGTVSSTVLKNLMSLTEYQI 420

Query: 789  NVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPS 848
             V+ I        +  T  T A     D  +  V + S+ V+W       +GY I+Y+P 
Sbjct: 421  AVFAIYAHTASEGLRGTETTLALPMASDLLLYDVTENSMRVKWDAVPG-ASGYLILYAPL 479

Query: 849  VE---GSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSD 905
             E   G   E+ + ET   + LS L P  +Y +T+YA+   + S PV  Q+ T       
Sbjct: 480  TEGLAGDEKEMKIGETHTDIELSGLLPNTEYTVTVYAMFGEEASDPVTGQETTL------ 533

Query: 906  TVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVT 965
             +  PR+L+   V      + W P    + GYR  ++  N  G     + +   T   + 
Sbjct: 534  ALSPPRNLRISNVGSNSARLTWDPTSRQINGYR--IVYNNADGTEINEVEVDPITTFPLK 591

Query: 966  GLSPGVTYYFKVFAVSHGRESKPLTAQQTT-KLDAPTNLQFVNETDSTVLVRWTPPRAQI 1024
            GL+P   Y   +F++    +S+PLT   TT ++ A   L+    T  +  V W P  A  
Sbjct: 592  GLTPLTEYTIAIFSIYDEGQSEPLTGVFTTEEVPAQQYLEIDEVTTDSFRVTWHPLSADE 651

Query: 1025 TGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAI-KGNQESPKATGVFT 1083
              ++L       G+  +  +      + +  L+P +EY VSL+A+     ES   T V T
Sbjct: 652  GLHKLMWIPVYGGKTEEVVLKEEQDSHVIEGLEPGTEYEVSLLAVLDDGSESEVVTAVGT 711

Query: 1084 TL-----QPGSSIPPYNT---------------EVTETTIVITW--TPAPRIGFKLGVRP 1121
            TL     +P ++I P  +               + T +++ + W  + +    F++    
Sbjct: 712  TLDSFWTEPATTIVPTTSVTSVFQTGIRNLVVGDETTSSLRVKWDISDSDVQQFRVTYMT 771

Query: 1122 SQGGEAPRE-------VTSDSGSIVVSGLTPGVEYVYTI-QVLRDGQERDAPIVNKVVTP 1173
            +QG   P E       V     ++++  L P  EY  T+  +  DG+        K + P
Sbjct: 772  AQGD--PEEEVIGTVMVPGSQNNLLLKPLLPDTEYKVTVTPIYTDGEGVSVSAPGKTL-P 828

Query: 1174 LSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCT 1233
             S P NL + +      L ++W+  ++P + GYRI   P +   G +LE  V AD ++  
Sbjct: 829  SSGPQNLRV-SEEWYNRLRITWDPPSSP-VKGYRIVYKPVS-VPGPTLETFVGADINTIL 885

Query: 1234 FDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSI 1293
              NL  G++YNV ++  +    S  ++  +       T+L+  ++   ++   W      
Sbjct: 886  ITNLLSGMDYNVKIFASQASGFSDALTGMVKTLFLGVTNLQAKHVEMTSLCAHWQVHRHA 945

Query: 1294 DLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGR 1353
                 ++     + ++   E ++           L P +EY +SV +  ++ E   +   
Sbjct: 946  TAYRVVIESLQDRQKQ---ESTVGGGTTRHCFYGLQPDSEYKISVYTKLQEIEGPSVSIM 1002

Query: 1354 QKT 1356
            +KT
Sbjct: 1003 EKT 1005



 Score =  140 bits (354), Expect = 1e-32
 Identities = 142/603 (23%), Positives = 244/603 (40%), Gaps = 86/603 (14%)

Query: 1545 PSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQP 1604
            P+++  ++V   S  V W  +   V  YRV   P  G  P +    G   + + ++ L  
Sbjct: 356  PTELITSEVTARSFMVNWTHAPGNVEKYRVVYYPTRGGKPDEVVVDGTVSSTV-LKNLMS 414

Query: 1605 TVEYVVSVYAQNPSGESQPLVQTAVT-NIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYR 1663
              EY ++V+A      S+ L  T  T  +     L   DV  +S+++ W++  G  S Y 
Sbjct: 415  LTEYQIAVFAIYAHTASEGLRGTETTLALPMASDLLLYDVTENSMRVKWDAVPG-ASGYL 473

Query: 1664 VTYSSPEDGIH-ELFPAPDGEEDT-AELQGLRPGSEYTVSVVALHDDMESQPLIGTQST- 1720
            + Y+   +G+  +      GE  T  EL GL P +EYTV+V A+  +  S P+ G ++T 
Sbjct: 474  ILYAPLTEGLAGDEKEMKIGETHTDIELSGLLPNTEYTVTVYAMFGEEASDPVTGQETTL 533

Query: 1721 AIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVS 1780
            A+  P +L+ + V   S    W P + Q+ GYR+     + T  + E+ + P  ++  + 
Sbjct: 534  ALSPPRNLRISNVGSNSARLTWDPTSRQINGYRIVYNNADGT-EINEVEVDP-ITTFPLK 591

Query: 1781 GLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTET 1840
            GL   T+Y ++++++ D   S P  GV TT E V   +   + + T  +  ++W   +  
Sbjct: 592  GLTPLTEYTIAIFSIYDEGQSEPLTGVFTT-EEVPAQQYLEIDEVTTDSFRVTWHPLSAD 650

Query: 1841 ITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDAS 1900
                ++  +P  G    +  +K +  S+ I GL+PGT+Y++ L  + D+   S VV    
Sbjct: 651  EGLHKLMWIPVYGGKTEEVVLKEEQDSHVIEGLEPGTEYEVSLLAVLDDGSESEVVTAVG 710

Query: 1901 TAIDA-------------------PSNLRFLAT---TPNSLLVSWQPPRARITGYIIKY- 1937
            T +D+                    + +R L     T +SL V W    + +  + + Y 
Sbjct: 711  TTLDSFWTEPATTIVPTTSVTSVFQTGIRNLVVGDETTSSLRVKWDISDSDVQQFRVTYM 770

Query: 1938 EKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLI-GRKKTVQKTP 1996
               G P  EV+                     T+ V   +NN   +PL+   +  V  TP
Sbjct: 771  TAQGDPEEEVIG--------------------TVMVPGSQNNLLLKPLLPDTEYKVTVTP 810

Query: 1997 FVTHPGYDTGNGIQLPGTSGQQPSVGQQMIFEEHGFRRTTPPTTATPIRHRPRPYPPNVG 2056
                  Y  G G+ +       PS G Q +                            V 
Sbjct: 811  I-----YTDGEGVSVSAPGKTLPSSGPQNL---------------------------RVS 838

Query: 2057 QEALSQTTISW-APFQDTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNII 2115
            +E  ++  I+W  P      Y I   PV      L+  V     +  +T L  G  YN+ 
Sbjct: 839  EEWYNRLRITWDPPSSPVKGYRIVYKPVSVPGPTLETFVGADINTILITNLLSGMDYNVK 898

Query: 2116 VEA 2118
            + A
Sbjct: 899  IFA 901



 Score =  100 bits (248), Expect = 2e-20
 Identities = 130/581 (22%), Positives = 232/581 (39%), Gaps = 53/581 (9%)

Query: 624  NSHPIQWNAPQPSHISKYILRWRP--KNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQL 681
            NS  ++W+A   +  S Y++ + P  +   G  KE  I        + GL P   Y    
Sbjct: 457  NSMRVKWDAVPGA--SGYLILYAPLTEGLAGDEKEMKIGETHTDIELSGLLPNTEYT--- 511

Query: 682  ISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWV 741
                      VT +       S PVT    T   +P   L      ++ + ++S  ++W 
Sbjct: 512  ----------VTVYAMFGEEASDPVTGQETTLALSPPRNL-----RISNVGSNSARLTWD 556

Query: 742  SASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSL 801
              S  ++G+R+ Y  + +G E   +++    T+  +  L P  +Y + ++ I ++G+   
Sbjct: 557  PTSRQINGYRIVYN-NADGTEINEVEV-DPITTFPLKGLTPLTEYTIAIFSIYDEGQSEP 614

Query: 802  ILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPET 861
            +     T    A     +D+V   S  V W    A    +++++ P   G + E+ L E 
Sbjct: 615  LTGVFTTEEVPAQQYLEIDEVTTDSFRVTWHPLSADEGLHKLMWIPVYGGKTEEVVLKEE 674

Query: 862  ANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETT-----GTPRSDTVPSP------ 910
             +S  +  L+PG +Y +++ AV ++   + VV    TT       P +  VP+       
Sbjct: 675  QDSHVIEGLEPGTEYEVSLLAVLDDGSESEVVTAVGTTLDSFWTEPATTIVPTTSVTSVF 734

Query: 911  ----RDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEH----GQRLPISRNTFA 962
                R+L   + T   + + W   +S V  +RV  +      E        +P S+N   
Sbjct: 735  QTGIRNLVVGDETTSSLRVKWDISDSDVQQFRVTYMTAQGDPEEEVIGTVMVPGSQNNLL 794

Query: 963  EVTGLSPGVTYYFKVFAVSHGRESKPLTAQ-QTTKLDAPTNLQFVNETDSTVLVRWTPPR 1021
             +  L P   Y   V  +    E   ++A  +T     P NL+   E  + + + W PP 
Sbjct: 795  -LKPLLPDTEYKVTVTPIYTDGEGVSVSAPGKTLPSSGPQNLRVSEEWYNRLRITWDPPS 853

Query: 1022 AQITGYRLTV-GLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG 1080
            + + GYR+    ++  G   +  VG  ++   + NL    +Y V + A + +  S   TG
Sbjct: 854  SPVKGYRIVYKPVSVPGPTLETFVGADINTILITNLLSGMDYNVKIFASQASGFSDALTG 913

Query: 1081 VFTTLQPG-SSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSI- 1138
            +  TL  G +++   + E+  T++   W           V  S      +E T   G+  
Sbjct: 914  MVKTLFLGVTNLQAKHVEM--TSLCAHWQVHRHATAYRVVIESLQDRQKQESTVGGGTTR 971

Query: 1139 -VVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPT 1178
                GL P  E  Y I V    QE + P V+ +    S PT
Sbjct: 972  HCFYGLQPDSE--YKISVYTKLQEIEGPSVSIMEKTQSLPT 1010



 Score = 64.7 bits (156), Expect = 1e-09
 Identities = 59/252 (23%), Positives = 106/252 (42%), Gaps = 36/252 (14%)

Query: 1765 MKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLEN----------- 1813
            ++EI   PDS+ V          Y V+ + L  T+     + + + +E            
Sbjct: 302  LQEIASEPDSTHV----------YNVAEFDLMHTVVESLTRTLCSRVEEQDREIKASAHA 351

Query: 1814 -VSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITG 1872
               PP     ++ T  +  ++W      +  ++V   P  G  P +  +   V S  +  
Sbjct: 352  ITGPPTELITSEVTARSFMVNWTHAPGNVEKYRVVYYPTRGGKPDEVVVDGTVSSTVLKN 411

Query: 1873 LQPGTDYK-----IYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQP-P 1926
            L   T+Y+     IY +T ++  R +    + + A+   S+L     T NS+ V W   P
Sbjct: 412  LMSLTEYQIAVFAIYAHTASEGLRGT----ETTLALPMASDLLLYDVTENSMRVKWDAVP 467

Query: 1927 RARITGYIIKYE--KPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEP 1984
             A  +GY+I Y     G    E   +     T+  ++GL P TEYT+ V A+   + S+P
Sbjct: 468  GA--SGYLILYAPLTEGLAGDEKEMKIGETHTDIELSGLLPNTEYTVTVYAMFGEEASDP 525

Query: 1985 LIGRKKTVQKTP 1996
            + G++ T+  +P
Sbjct: 526  VTGQETTLALSP 537



 Score = 53.1 bits (126), Expect = 3e-06
 Identities = 31/106 (29%), Positives = 51/106 (48%), Gaps = 4/106 (3%)

Query: 1722 IPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSG 1781
            +  PT L++  ++  S+   W  P  +  GY++ VTP    G   ++NL   ++  ++ G
Sbjct: 30   VAPPTRLRYNVISHDSIQISWKAPRGKFGGYKLLVTPTSG-GKTNQLNLQNTATKAIIQG 88

Query: 1782 LMVATKYEVSVYALKDTLTSRPAQGV--VTTLENVSPPR-RARVTD 1824
            LM    Y V + A      S+PAQG   +  LE    P+ R +V D
Sbjct: 89   LMPDQNYTVQIIAYNKDKESKPAQGQFRIKDLEKRKDPKPRVKVVD 134



 Score = 50.1 bits (118), Expect = 3e-05
 Identities = 21/70 (30%), Positives = 36/70 (51%)

Query: 822 VDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIY 881
           +   SI + W  P+    GY+++ +P+  G + +LNL  TA    +  L P   Y + I 
Sbjct: 41  ISHDSIQISWKAPRGKFGGYKLLVTPTSGGKTNQLNLQNTATKAIIQGLMPDQNYTVQII 100

Query: 882 AVEENQESTP 891
           A  +++ES P
Sbjct: 101 AYNKDKESKP 110



 Score = 45.8 bits (107), Expect = 5e-04
 Identities = 23/83 (27%), Positives = 39/83 (46%), Gaps = 1/83 (1%)

Query: 1541 EIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIE 1600
            ++  P++++   +  +SI + W        GY++  TP +G G T         T+  I+
Sbjct: 29   QVAPPTRLRYNVISHDSIQISWKAPRGKFGGYKLLVTPTSG-GKTNQLNLQNTATKAIIQ 87

Query: 1601 GLQPTVEYVVSVYAQNPSGESQP 1623
            GL P   Y V + A N   ES+P
Sbjct: 88   GLMPDQNYTVQIIAYNKDKESKP 110



 Score = 45.8 bits (107), Expect = 5e-04
 Identities = 31/107 (28%), Positives = 52/107 (48%), Gaps = 5/107 (4%)

Query: 1906 PSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEP 1965
            P+ LR+   + +S+ +SW+ PR +  GY +    P S  +      +   T+A I GL P
Sbjct: 33   PTRLRYNVISHDSIQISWKAPRGKFGGYKLLVT-PTSGGKTNQLNLQNTATKAIIQGLMP 91

Query: 1966 GTEYTIYVIALKNNQKSEPLIGRKK----TVQKTPFVTHPGYDTGNG 2008
               YT+ +IA   +++S+P  G+ +      +K P       D GNG
Sbjct: 92   DQNYTVQIIAYNKDKESKPAQGQFRIKDLEKRKDPKPRVKVVDRGNG 138



 Score = 41.6 bits (96), Expect = 0.009
 Identities = 21/81 (25%), Positives = 35/81 (43%)

Query: 1814 VSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGL 1873
            V+PP R R    +  +I ISW+       G+++   P +G    Q  ++       I GL
Sbjct: 30   VAPPTRLRYNVISHDSIQISWKAPRGKFGGYKLLVTPTSGGKTNQLNLQNTATKAIIQGL 89

Query: 1874 QPGTDYKIYLYTLNDNARSSP 1894
             P  +Y + +   N +  S P
Sbjct: 90   MPDQNYTVQIIAYNKDKESKP 110



 Score = 32.3 bits (72), Expect = 5.6
 Identities = 31/123 (25%), Positives = 52/123 (42%), Gaps = 11/123 (8%)

Query: 731 ITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNV 790
           I+  S  +SW +      G+++    +  G   Q L+L +TAT   I  L+P + Y V +
Sbjct: 41  ISHDSIQISWKAPRGKFGGYKLLVTPTSGGKTNQ-LNLQNTATKAIIQGLMPDQNYTVQI 99

Query: 791 YQISEDGEQSLILSTSQTTAPD----APPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYS 846
              ++D E     +  Q    D      P P V  VD  +     SRP +P     +  +
Sbjct: 100 IAYNKDKESK--PAQGQFRIKDLEKRKDPKPRVKVVDRGN----GSRPSSPEEVKFVCQT 153

Query: 847 PSV 849
           P++
Sbjct: 154 PAI 156


>gi|222352127 sidekick 2 [Homo sapiens]
          Length = 2172

 Score =  164 bits (416), Expect = 7e-40
 Identities = 278/1176 (23%), Positives = 459/1176 (39%), Gaps = 172/1176 (14%)

Query: 923  VTIMWTPP---ESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFA 979
            + + WT P    S +  Y +++   N P          + T   V GL P  +Y F++ A
Sbjct: 608  INLTWTKPFDGNSPLIRYILEMSENNAPWTVLLASVDPKATSVTVKGLVPARSYQFRLCA 667

Query: 980  VSH------GRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQ-----ITGYR 1028
            V+        ++++ ++  +      P N+     T+ +++++W PP        + GY 
Sbjct: 668  VNDVGKGQFSKDTERVSLPEEPPTAPPQNVIASGRTNQSIMIQWQPPPESHQNGILKGYI 727

Query: 1029 LTVGLTRRGQPRQYN----VGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFT- 1083
            +   L   G P  Y         V+   L +L   + Y + + A           GV++ 
Sbjct: 728  IRYCLA--GLPVGYQFKNITDADVNNLLLEDLIIWTNYEIEVAAYNS-----AGLGVYSS 780

Query: 1084 -----TLQPGSSIPPYNTEV---TETTIVITWT-PAPRI------GFKLGVRPSQGGEAP 1128
                 TLQ   ++PP N        TTI  TW  P+P+       G+KL     +  E  
Sbjct: 781  KVTEWTLQGVPTVPPGNVHAEATNSTTIRFTWNAPSPQFINGINQGYKLIAWEPEQEEEV 840

Query: 1129 REVTS-----DSGSI-VVSGLTPGVEYVYTIQVLR---DGQERDAPIVNKVVTPLSPPTN 1179
              VT+     DS  +  VSGL    EY  ++       DG      +V        P  +
Sbjct: 841  TMVTARPNFQDSIHVGFVSGLKKFTEYFTSVLCFTTPGDGPRSTPQLVRTHEDVPGPVGH 900

Query: 1180 LHLEANPDTGVLTVSWERSTTPD--ITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNL 1237
            L      DT  L VSW+     +  +TGYRI+    N     +   V H    + T +  
Sbjct: 901  LSFSEILDTS-LKVSWQEPGEKNGILTGYRISWEEYN----RTNTRVTHY-LPNVTLEYR 954

Query: 1238 SPGLE----YNVSVYTVKDDKESVPISDTIIPAVPP-----PTDLRFTNIGPDTMRVTWA 1288
              GL     Y + V  +    +    + TI   VPP     PT+L  +NIGP ++ + + 
Sbjct: 955  VTGLTALTTYTIEVAAMTSKGQGQVSASTISSGVPPELPGPPTNLGISNIGPRSVTLQFR 1014

Query: 1289 P--PPSIDLTNFLV--RYSPVKNEED---VAELSISPSDNAVVLTNLLPGTEYVVSVSSV 1341
            P       ++ +LV  +   V   E+   + +LS  P   ++ + +L P T Y   +  V
Sbjct: 1015 PGYDGKTSISRWLVEAQVGVVGEGEEWLLIHQLSNEPDARSMEVPDLNPFTCYSFRMRQV 1074

Query: 1342 YEQHESTPLRGRQKTGL------DSPTGIDFSDITANSFTVHWIA-------PRATITGY 1388
                 S P +  +K          +P  +     +  S  + W+              GY
Sbjct: 1075 NIVGTSPPSQPSRKIQTLQAPPDMAPANVSLRTASETSLWLRWMPLPEMEYNGNPESVGY 1134

Query: 1389 RIRHHPEHFSGRPR----EDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESP---LLI 1441
            +I++      G+      +DRV       T+ +L   TEY V + A N     P    ++
Sbjct: 1135 KIKYSRSDGHGKTLSHVVQDRV---ERDYTIEDLEEWTEYRVQVQAFNAIGSGPWSQTVV 1191

Query: 1442 GQ--QSTVSDVPRDLEVVAATPTSLLISW-DAPAVT----VRYYRITYGETGGNSPVQEF 1494
            G+  +S  S  P ++  +A T +S+L+ W + P       V  Y++ Y E   ++  + +
Sbjct: 1192 GRTRESVPSSGPTNVSALATTSSSMLVRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFW 1251

Query: 1495 TVPGSKS-TATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQ-MQVTD 1552
             V G+ S +A ++GL   V Y + V A T  GD   S  PI      ++  P   +   +
Sbjct: 1252 LVEGNSSRSAQLTGLGKYVLYEVQVLAFTRIGDGSPSHPPILERTLDDVPGPPMGILFPE 1311

Query: 1553 VQDNSISVKWLPSSSP---VTGYRVTTTPKNGPGPTKT-KTAGPDQTEMTIEGLQPTVEY 1608
            V+  S+ + W P ++P   +  Y++T         T T +   P   + T  GL+P   Y
Sbjct: 1312 VRTTSVRLIWQPPAAPNGIILAYQITHRLNTTTANTATVEVLAPSARQYTATGLKPESVY 1371

Query: 1609 VVSVYAQNPSGESQPLVQTAVTNI--DRPKG-----LAFTDVDVDSIKIAWESPQGQVSR 1661
            +  + AQ   G  +      VT    DRP+      +   DV   S+ ++WE     +S 
Sbjct: 1372 LFRITAQTRKGWGEAAEALVVTTEKRDRPQPPSRPMVQQEDVRARSVLLSWEPGSDGLSP 1431

Query: 1662 ---YRVTYSSPEDGIHELFPAPDGEEDTAEL-QGLRPGSEYTVSVVALHD------DMES 1711
               Y +       G   L  A      ++ +   L+P + Y   V A +D        ES
Sbjct: 1432 VRYYTIQTRELPSGRWALHSASVSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEES 1491

Query: 1712 QPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPP-----NVQLTGYRVR----------- 1755
            + L   Q+    APT L  T  T TS+  +W PP     N  L G+R+R           
Sbjct: 1492 ESLTTLQAAPDEAPTILSVTPHTTTSVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRG 1551

Query: 1756 ----------VTPKEKTGPMKEINLA-PDSSSVVVSGLMVATKYEV--SVY-ALKDTLTS 1801
                       T  E T      NL+ P  +   +  L    +YE+  SVY A+ +  +S
Sbjct: 1552 FTLRGINNPGATWAELTSMYSMRNLSRPSLTQYELDNLNKHRRYEIRMSVYNAVGEGPSS 1611

Query: 1802 RPAQGVVTTLENVSPPRRARVTDATETTITISWR-----TKTETITGFQVDAVPANGQTP 1856
             P +  V      + PR   V  AT T + ++W      ++   I G+++    A     
Sbjct: 1612 PPQEVFVGEAVPTAAPRNVVVHGATATQLDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNL 1671

Query: 1857 IQR--TIKPDVRSYTITGLQPGTDYKIYLYTLN---DNARSSPVVIDASTAI-DAPSNLR 1910
             +R  T+     S  +  L   T Y + +   N   D  RS+P       A   APS+++
Sbjct: 1672 TERVKTLFLAENSVKLKNLTGYTAYMVSVAAFNAAGDGPRSTPTQGQTQQAAPSAPSSVK 1731

Query: 1911 FLATTPNSLLVSWQPPR---ARITGYIIKYEKPGSP 1943
            F   T  S+ VSW+ P+     + GY + YE P SP
Sbjct: 1732 FSELTTTSVNVSWEAPQFPNGILEGYRLVYE-PCSP 1766



 Score =  156 bits (395), Expect = 2e-37
 Identities = 286/1279 (22%), Positives = 473/1279 (36%), Gaps = 170/1279 (13%)

Query: 772  ATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQV-----DDTS 826
            ATSV +  L+P R Y   +  +++ G+      T + + P+ PP      V      + S
Sbjct: 647  ATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSLPEEPPTAPPQNVIASGRTNQS 706

Query: 827  IVVRWSRP-----QAPITGYRIVY--SPSVEGSSTELNLPETANSVTLSDLQPGVQYNIT 879
            I+++W  P        + GY I Y  +    G   +       N++ L DL     Y I 
Sbjct: 707  IMIQWQPPPESHQNGILKGYIIRYCLAGLPVGYQFKNITDADVNNLLLEDLIIWTNYEIE 766

Query: 880  IYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAV----- 934
            + A   N     V   + T  T +      P ++         +   W  P         
Sbjct: 767  VAAY--NSAGLGVYSSKVTEWTLQGVPTVPPGNVHAEATNSTTIRFTWNAPSPQFINGIN 824

Query: 935  TGYRVDVIPVNLPGEHGQRLPISRNTFAE------VTGLSPGVTYYFKVFAVS---HGRE 985
             GY+  +I      E    +  +R  F +      V+GL     Y+  V   +    G  
Sbjct: 825  QGYK--LIAWEPEQEEEVTMVTARPNFQDSIHVGFVSGLKKFTEYFTSVLCFTTPGDGPR 882

Query: 986  SKPLTAQQTTKLDAPT-NLQFVNETDSTVLVRWTPPRAQ---ITGYRLTVGLTRRGQPRQ 1041
            S P   +    +  P  +L F    D+++ V W  P  +   +TGYR++     R   R 
Sbjct: 883  STPQLVRTHEDVPGPVGHLSFSEILDTSLKVSWQEPGEKNGILTGYRISWEEYNRTNTRV 942

Query: 1042 YNVGPSVS-KYPLRNLQPASEYTVSLVAIKG-NQESPKATGVFTTLQPGSSIPPYNTEVT 1099
             +  P+V+ +Y +  L   + YT+ + A+    Q    A+ + + + P    PP N  ++
Sbjct: 943  THYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQVSASTISSGVPPELPGPPTNLGIS 1002

Query: 1100 E----------------TTIVITWTPAPRIGFKLGVRPSQGGEAPREVTS--DSGSIVVS 1141
                              T +  W    ++G    V   +      ++++  D+ S+ V 
Sbjct: 1003 NIGPRSVTLQFRPGYDGKTSISRWLVEAQVGV---VGEGEEWLLIHQLSNEPDARSMEVP 1059

Query: 1142 GLTPGVEYVYTI-QVLRDGQERDAPIVNKVVTPLSP----PTNLHLEANPDTGVLTVSW- 1195
             L P   Y + + QV   G    +    K+ T  +P    P N+ L    +T  L + W 
Sbjct: 1060 DLNPFTCYSFRMRQVNIVGTSPPSQPSRKIQTLQAPPDMAPANVSLRTASETS-LWLRWM 1118

Query: 1196 -----ERSTTPDITGYRITTTPTNGQQGNSLEEVVH-ADQSSCTFDNLSPGLEYNVSVYT 1249
                 E +  P+  GY+I  + ++G  G +L  VV    +   T ++L    EY V V  
Sbjct: 1119 PLPEMEYNGNPESVGYKIKYSRSDG-HGKTLSHVVQDRVERDYTIEDLEEWTEYRVQVQA 1177

Query: 1250 VKDDKESVPISDTII----PAVPP--PTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYS 1303
              +   S P S T++     +VP   PT++        +M V W+  P  D    ++ Y 
Sbjct: 1178 F-NAIGSGPWSQTVVGRTRESVPSSGPTNVSALATTSSSMLVRWSEVPEADRNGLVLGYK 1236

Query: 1304 PVKNEEDVAE-----LSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTP-----LRGR 1353
             +  E+D        L    S  +  LT L     Y V V +     + +P     L   
Sbjct: 1237 VMYKEKDSDTQPRFWLVEGNSSRSAQLTGLGKYVLYEVQVLAFTRIGDGSPSHPPILERT 1296

Query: 1354 QKTGLDSPTGIDFSDITANSFTVHW---IAPRATITGYRIRHHPEHFSGRPREDRV-PHS 1409
                   P GI F ++   S  + W    AP   I  Y+I H     +       V   S
Sbjct: 1297 LDDVPGPPMGILFPEVRTTSVRLIWQPPAAPNGIILAYQITHRLNTTTANTATVEVLAPS 1356

Query: 1410 RNSITLTNLTPGTEYVVSIVALN----GREESPLLIGQQSTVSDVPRDLEVVA---ATPT 1462
                T T L P + Y+  I A      G     L++  +      P    +V        
Sbjct: 1357 ARQYTATGLKPESVYLFRITAQTRKGWGEAAEALVVTTEKRDRPQPPSRPMVQQEDVRAR 1416

Query: 1463 SLLISWDAPA---VTVRYYRITYGE-TGGNSPVQEFTVPGSKSTATISGLKPGVDYTITV 1518
            S+L+SW+  +     VRYY I   E   G   +   +V  + S+  +  LKP   Y   V
Sbjct: 1417 SVLLSWEPGSDGLSPVRYYTIQTRELPSGRWALHSASVSHNASSFIVDRLKPFTSYKFRV 1476

Query: 1519 YAVTGRGDSPAS--SKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSP-----VTG 1571
             A    GDS  S  S+ ++       + P+ + VT     S+ ++W P +       + G
Sbjct: 1477 KATNDIGDSEFSEESESLTTLQAAPDEAPTILSVTPHTTTSVLIRWQPPAEDKINGILLG 1536

Query: 1572 YRV-------------TTTPKNGPGPTKTKTAG---------PDQTEMTIEGLQPTVEYV 1609
            +R+             T    N PG T  +            P  T+  ++ L     Y 
Sbjct: 1537 FRIRYRELLYEGLRGFTLRGINNPGATWAELTSMYSMRNLSRPSLTQYELDNLNKHRRYE 1596

Query: 1610 V--SVY---AQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESP-----QGQV 1659
            +  SVY    + PS   Q +          P+ +         + + WE P      G +
Sbjct: 1597 IRMSVYNAVGEGPSSPPQEVFVGEAVPTAAPRNVVVHGATATQLDVTWEPPPLDSQNGDI 1656

Query: 1660 SRYRVTYSSPEDG-----IHELFPAPDGEEDTAELQGLRPGSEYTVSVVALH---DDMES 1711
              Y++ +   + G     +  LF A    E++ +L+ L   + Y VSV A +   D   S
Sbjct: 1657 QGYKIYFWEAQRGNLTERVKTLFLA----ENSVKLKNLTGYTAYMVSVAAFNAAGDGPRS 1712

Query: 1712 QPLIG-TQSTAIPAPTDLKFTQVTPTSLSAQWTP---PNVQLTGYRVRVTP-KEKTGPMK 1766
             P  G TQ  A  AP+ +KF+++T TS++  W     PN  L GYR+   P     G  K
Sbjct: 1713 TPTQGQTQQAAPSAPSSVKFSELTTTSVNVSWEAPQFPNGILEGYRLVYEPCSPVDGVSK 1772

Query: 1767 EINLAPDSSS---VVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSP-PRRARV 1822
             + +    +S   + V  L     Y   + A   T        V T     +P P    +
Sbjct: 1773 IVTVDVKGNSPLWLKVKDLAEGVTYRFRIRAKTFTYGPEIEANVTTGPGEGAPGPPGVPI 1832

Query: 1823 TDATETTITISWRTKTE---TITGFQVDAVPAN-GQTPIQ-RTIKPDVRSYTITG--LQP 1875
                 + I I W +       IT + ++A P++ G   I  + I  +V SYT +   L+P
Sbjct: 1833 IVRYSSAIAIHWSSGDPGKGPITRYVIEARPSDEGLWDILIKDIPKEVSSYTFSMDILKP 1892

Query: 1876 GTDYKIYLYTLNDNARSSP 1894
            G  Y   +  +ND    +P
Sbjct: 1893 GVSYDFRVIAVNDYGFGTP 1911



 Score =  136 bits (342), Expect = 3e-31
 Identities = 260/1236 (21%), Positives = 460/1236 (37%), Gaps = 179/1236 (14%)

Query: 594  IGEWHCQPLQTYPSSSGPVEVFITETPSQPNSHPIQ-------------WNAPQP--SHI 638
            IG + C+ +    + S    + + + P  P  HP+              W  P    S +
Sbjct: 564  IGTYTCRVISAGGNDSRSAHLRVRQLPHAPE-HPVATLSTVERRAINLTWTKPFDGNSPL 622

Query: 639  SKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFT 698
             +YIL     N+      A++     S T+KGL P   Y+ +L ++   G  +   F   
Sbjct: 623  IRYILEMSENNAPWTVLLASVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQ---FSKD 679

Query: 699  TTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDT-----VSGFRVE 753
            T   S P         T P   ++A+       T  S ++ W    ++     + G+ + 
Sbjct: 680  TERVSLPEEP-----PTAPPQNVIASGR-----TNQSIMIQWQPPPESHQNGILKGYIIR 729

Query: 754  YELSEEGDEPQYLDL-PSTATSVNIPDLLPGRKYIVNVYQISEDG---EQSLILSTSQTT 809
            Y L+      Q+ ++  +   ++ + DL+    Y + V   +  G     S +   +   
Sbjct: 730  YCLAGLPVGYQFKNITDADVNNLLLEDLIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQG 789

Query: 810  APDAPP-DPTVDQVDDTSIVVRWSRPQAPI-----TGYRIV-YSPSVEGSSTEL----NL 858
             P  PP +   +  + T+I   W+ P          GY+++ + P  E   T +    N 
Sbjct: 790  VPTVPPGNVHAEATNSTTIRFTWNAPSPQFINGINQGYKLIAWEPEQEEEVTMVTARPNF 849

Query: 859  PETANSVTLSDLQPGVQYNITIYAVE---ENQESTPVVIQQETTGTPRSDTVPSP-RDLQ 914
             ++ +   +S L+   +Y  ++       +   STP +++         + VP P   L 
Sbjct: 850  QDSIHVGFVSGLKKFTEYFTSVLCFTTPGDGPRSTPQLVRTH-------EDVPGPVGHLS 902

Query: 915  FVEVTDVKVTIMWTPP---ESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGV 971
            F E+ D  + + W  P      +TGYR+     N           +      VTGL+   
Sbjct: 903  FSEILDTSLKVSWQEPGEKNGILTGYRISWEEYNRTNTRVTHYLPNVTLEYRVTGLTALT 962

Query: 972  TYYFKVFAVSHGRESKPLTAQQTTKL-----DAPTNLQFVNETDSTVLVRWTP---PRAQ 1023
            TY  +V A++   + +   +  ++ +       PTNL   N    +V +++ P    +  
Sbjct: 963  TYTIEVAAMTSKGQGQVSASTISSGVPPELPGPPTNLGISNIGPRSVTLQFRPGYDGKTS 1022

Query: 1024 ITGY--RLTVGLTRRGQP----RQYNVGPSVSKYPLRNLQPASEYTVSL--VAIKGNQES 1075
            I+ +     VG+   G+      Q +  P      + +L P + Y+  +  V I G    
Sbjct: 1023 ISRWLVEAQVGVVGEGEEWLLIHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVGTSPP 1082

Query: 1076 PKATGVFTTLQPGSSIPPYNTEV---TETTIVITWTPAPR---------IGFKLGVRPSQ 1123
             + +    TLQ    + P N  +   +ET++ + W P P          +G+K+    S 
Sbjct: 1083 SQPSRKIQTLQAPPDMAPANVSLRTASETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSD 1142

Query: 1124 G-GEAPREVTSD--SGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVV------TPL 1174
            G G+    V  D       +  L    E  Y +QV         P    VV       P 
Sbjct: 1143 GHGKTLSHVVQDRVERDYTIEDLEEWTE--YRVQVQAFNAIGSGPWSQTVVGRTRESVPS 1200

Query: 1175 SPPTNLHLEANPDTGVLTVSWERSTTPD----ITGYRITTTPTNGQQGNSLEEVVHADQS 1230
            S PTN+   A   + +L V W      D    + GY++     +         V      
Sbjct: 1201 SGPTNVSALATTSSSML-VRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSR 1259

Query: 1231 SCTFDNLSPGLEYNVSVYT---VKDDKES-VPISDTIIPAVP-PPTDLRFTNIGPDTMRV 1285
            S     L   + Y V V     + D   S  PI +  +  VP PP  + F  +   ++R+
Sbjct: 1260 SAQLTGLGKYVLYEVQVLAFTRIGDGSPSHPPILERTLDDVPGPPMGILFPEVRTTSVRL 1319

Query: 1286 TWAPP--PSIDLTNFLVRYSPVKNEEDVAELSI-SPSDNAVVLTNLLPGTEYVVSVSSVY 1342
             W PP  P+  +  + + +       + A + + +PS      T L P + Y+  +++  
Sbjct: 1320 IWQPPAAPNGIILAYQITHRLNTTTANTATVEVLAPSARQYTATGLKPESVYLFRITAQT 1379

Query: 1343 -----EQHESTPLRGRQKTGLDSPTG--IDFSDITANSFTVHWIAPR---ATITGYRIRH 1392
                 E  E+  +   ++     P+   +   D+ A S  + W       + +  Y I+ 
Sbjct: 1380 RKGWGEAAEALVVTTEKRDRPQPPSRPMVQQEDVRARSVLLSWEPGSDGLSPVRYYTIQT 1439

Query: 1393 HPEHFSGR--PREDRVPHSRNSITLTNLTPGTEYVVSIVALNG------REESPLLIGQQ 1444
              E  SGR       V H+ +S  +  L P T Y   + A N        EES  L   Q
Sbjct: 1440 R-ELPSGRWALHSASVSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQ 1498

Query: 1445 STVSDVPRDLEVVAATPTSLLISWDAPA----------VTVRYYRITY----GET--GGN 1488
            +   + P  L V   T TS+LI W  PA            +RY  + Y    G T  G N
Sbjct: 1499 AAPDEAPTILSVTPHTTTSVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGIN 1558

Query: 1489 SP------------VQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPAS-SKPIS 1535
            +P            ++  + P S +   +  L     Y I +      G+ P+S  + + 
Sbjct: 1559 NPGATWAELTSMYSMRNLSRP-SLTQYELDNLNKHRRYEIRMSVYNAVGEGPSSPPQEVF 1617

Query: 1536 INYRTEIDKPSQMQVTDVQDNSISVKWLP-----SSSPVTGYRV-TTTPKNGPGPTKTKT 1589
            +        P  + V       + V W P      +  + GY++     + G    + KT
Sbjct: 1618 VGEAVPTAAPRNVVVHGATATQLDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKT 1677

Query: 1590 AGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE---SQPLV-QTAVTNIDRPKGLAFTDVDV 1645
                +  + ++ L     Y+VSV A N +G+   S P   QT       P  + F+++  
Sbjct: 1678 LFLAENSVKLKNLTGYTAYMVSVAAFNAAGDGPRSTPTQGQTQQAAPSAPSSVKFSELTT 1737

Query: 1646 DSIKIAWESPQ---GQVSRYRVTYS--SPEDGIHEL 1676
             S+ ++WE+PQ   G +  YR+ Y   SP DG+ ++
Sbjct: 1738 TSVNVSWEAPQFPNGILEGYRLVYEPCSPVDGVSKI 1773



 Score =  123 bits (309), Expect = 2e-27
 Identities = 273/1262 (21%), Positives = 481/1262 (38%), Gaps = 173/1262 (13%)

Query: 606  PSSSGPVEVFITETPSQPNSHPIQWNAPQPSH----ISKYILRWRPKN-SVGRWKEATIP 660
            P ++ P  V  +   +Q  S  IQW  P  SH    +  YI+R+      VG   +    
Sbjct: 689  PPTAPPQNVIASGRTNQ--SIMIQWQPPPESHQNGILKGYIIRYCLAGLPVGYQFKNITD 746

Query: 661  GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP 720
              +N+  ++ L   +++    I +  Y             S    V S+ VT  T    P
Sbjct: 747  ADVNNLLLEDL---IIWTNYEIEVAAYN------------SAGLGVYSSKVTEWTLQGVP 791

Query: 721  LVATSESVTEITASSFV-VSWVSASDT-VSGFRVEYEL-----SEEGDEPQYLDLPSTAT 773
             V       E T S+ +  +W + S   ++G    Y+L      +E +       P+   
Sbjct: 792  TVPPGNVHAEATNSTTIRFTWNAPSPQFINGINQGYKLIAWEPEQEEEVTMVTARPNFQD 851

Query: 774  SVNI---PDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDP---TVDQVDDTSI 827
            S+++     L    +Y  +V   +  G+          T  D P      +  ++ DTS+
Sbjct: 852  SIHVGFVSGLKKFTEYFTSVLCFTTPGDGPRSTPQLVRTHEDVPGPVGHLSFSEILDTSL 911

Query: 828  VVRWSRP---QAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVE 884
             V W  P      +TGYRI +    E + T   +     +VTL     G+   +T Y +E
Sbjct: 912  KVSWQEPGEKNGILTGYRISWE---EYNRTNTRVTHYLPNVTLEYRVTGLTA-LTTYTIE 967

Query: 885  ----ENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP---ESAVTGY 937
                 ++    V     ++G P     P P +L    +    VT+ + P    +++++ +
Sbjct: 968  VAAMTSKGQGQVSASTISSGVPPELPGP-PTNLGISNIGPRSVTLQFRPGYDGKTSISRW 1026

Query: 938  RVDVIPVNLPGEHGQRLPISRNT------FAEVTGLSPGVTYYFK---VFAVSHGRESKP 988
             V+   V + GE  + L I + +        EV  L+P   Y F+   V  V     S+P
Sbjct: 1027 LVEA-QVGVVGEGEEWLLIHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQP 1085

Query: 989  LTAQQTTKLD---APTNLQFVNETDSTVLVRWTP-PRAQITGYRLTVGLTRR-------G 1037
                QT +     AP N+     +++++ +RW P P  +  G   +VG   +       G
Sbjct: 1086 SRKIQTLQAPPDMAPANVSLRTASETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHG 1145

Query: 1038 QPRQYNVGPSVSK-YPLRNLQPASEYTVSLVAIKGNQESP-KATGVFTTLQPGSSIPPYN 1095
            +   + V   V + Y + +L+  +EY V + A       P   T V  T +   S  P N
Sbjct: 1146 KTLSHVVQDRVERDYTIEDLEEWTEYRVQVQAFNAIGSGPWSQTVVGRTRESVPSSGPTN 1205

Query: 1096 TEVTETT---IVITWTPAPR-------IGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTP 1145
                 TT   +++ W+  P        +G+K+  +       PR    +  S   + LT 
Sbjct: 1206 VSALATTSSSMLVRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSRSAQLTG 1265

Query: 1146 GVEYV-YTIQVLR-----DGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERST 1199
              +YV Y +QVL      DG     PI+ + +  +  P    L     T  + + W+   
Sbjct: 1266 LGKYVLYEVQVLAFTRIGDGSPSHPPILERTLDDVPGPPMGILFPEVRTTSVRLIWQPPA 1325

Query: 1200 TPD--ITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEY--NVSVYTVKDDKE 1255
             P+  I  Y+IT          +  EV+       T   L P   Y   ++  T K   E
Sbjct: 1326 APNGIILAYQITHRLNTTTANTATVEVLAPSARQYTATGLKPESVYLFRITAQTRKGWGE 1385

Query: 1256 S-----VPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEE- 1309
            +     V       P  P    ++  ++   ++ ++W P  S  L+   VRY  ++  E 
Sbjct: 1386 AAEALVVTTEKRDRPQPPSRPMVQQEDVRARSVLLSWEPG-SDGLSP--VRYYTIQTREL 1442

Query: 1310 -----DVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYE------QHESTPLRGRQKTGL 1358
                  +   S+S + ++ ++  L P T Y   V +  +        ES  L   Q    
Sbjct: 1443 PSGRWALHSASVSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPD 1502

Query: 1359 DSPTGIDFSDITANSFTVHWIAP-----RATITGYRIRHHPEHFSGRP----REDRVPH- 1408
            ++PT +  +  T  S  + W  P        + G+RIR+    + G      R    P  
Sbjct: 1503 EAPTILSVTPHTTTSVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGINNPGA 1562

Query: 1409 --------------SRNSIT---LTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDV- 1450
                          SR S+T   L NL     Y + +   N   E P    Q+  V +  
Sbjct: 1563 TWAELTSMYSMRNLSRPSLTQYELDNLNKHRRYEIRMSVYNAVGEGPSSPPQEVFVGEAV 1622

Query: 1451 ----PRDLEVVAATPTSLLISWDAPAVT-----VRYYRITYGETG-GNSPVQEFTVPGSK 1500
                PR++ V  AT T L ++W+ P +      ++ Y+I + E   GN   +  T+  ++
Sbjct: 1623 PTAAPRNVVVHGATATQLDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLFLAE 1682

Query: 1501 STATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISV 1560
            ++  +  L     Y ++V A    GD P S+       +     PS ++ +++   S++V
Sbjct: 1683 NSVKLKNLTGYTAYMVSVAAFNAAGDGPRSTPTQGQTQQAAPSAPSSVKFSELTTTSVNV 1742

Query: 1561 KWLPSSSP---VTGYRVTTTPKNG-PGPTKTKTA---GPDQTEMTIEGLQPTVEYVVSVY 1613
             W     P   + GYR+   P +   G +K  T    G     + ++ L   V Y   + 
Sbjct: 1743 SWEAPQFPNGILEGYRLVYEPCSPVDGVSKIVTVDVKGNSPLWLKVKDLAEGVTYRFRIR 1802

Query: 1614 AQNPSGESQPLVQTAVTN-----IDRPKGLAFTDVDVDSIKIAWESP---QGQVSRYRVT 1665
            A+  +    P ++  VT         P G+        +I I W S    +G ++RY + 
Sbjct: 1803 AKTFT--YGPEIEANVTTGPGEGAPGPPGVPIIVRYSSAIAIHWSSGDPGKGPITRYVIE 1860

Query: 1666 YSSPEDGIHELFPAPDGEED---TAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAI 1722
                ++G+ ++      +E    T  +  L+PG  Y   V+A++D     P   + S ++
Sbjct: 1861 ARPSDEGLWDILIKDIPKEVSSYTFSMDILKPGVSYDFRVIAVNDYGFGTP--SSPSQSV 1918

Query: 1723 PA 1724
            PA
Sbjct: 1919 PA 1920



 Score = 76.6 bits (187), Expect = 3e-13
 Identities = 102/446 (22%), Positives = 182/446 (40%), Gaps = 71/446 (15%)

Query: 600  QPLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATI 659
            + L T  ++       ++ TP    S  I+W  P    I+  +L +R      R++E   
Sbjct: 1492 ESLTTLQAAPDEAPTILSVTPHTTTSVLIRWQPPAEDKINGILLGFRI-----RYRELLY 1546

Query: 660  PGHLNSYTIKGLK-PGVVYEG--QLISIQQYGHQEVTRFDFTTTST-------------- 702
             G L  +T++G+  PG  +     + S++      +T+++    +               
Sbjct: 1547 EG-LRGFTLRGINNPGATWAELTSMYSMRNLSRPSLTQYELDNLNKHRRYEIRMSVYNAV 1605

Query: 703  ----STPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWV-----SASDTVSGFRVE 753
                S+P       GE  P +     +  V   TA+   V+W      S +  + G+++ 
Sbjct: 1606 GEGPSSP-PQEVFVGEAVPTA--APRNVVVHGATATQLDVTWEPPPLDSQNGDIQGYKIY 1662

Query: 754  YELSEEGDEPQYLDLPSTA-TSVNIPDLLPGRKYIVNV--YQISEDGEQSL-ILSTSQTT 809
            +  ++ G+  + +     A  SV + +L     Y+V+V  +  + DG +S      +Q  
Sbjct: 1663 FWEAQRGNLTERVKTLFLAENSVKLKNLTGYTAYMVSVAAFNAAGDGPRSTPTQGQTQQA 1722

Query: 810  APDAPPDPTVDQVDDTSIVVRWSRPQAP---ITGYRIVYSPS--VEGSSTELNLPETANS 864
            AP AP      ++  TS+ V W  PQ P   + GYR+VY P   V+G S  + +    NS
Sbjct: 1723 APSAPSSVKFSELTTTSVNVSWEAPQFPNGILEGYRLVYEPCSPVDGVSKIVTVDVKGNS 1782

Query: 865  ---VTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDV 921
               + + DL  GV Y   I A  +     P +    TTG    +  P P  +  +     
Sbjct: 1783 PLWLKVKDLAEGVTYRFRIRA--KTFTYGPEIEANVTTGP--GEGAPGPPGVPIIVRYSS 1838

Query: 922  KVTIMWT---PPESAVTGYRV----------DVIPVNLPGEHGQRLPISRNTFAEVTGLS 968
             + I W+   P +  +T Y +          D++  ++P E      +S  TF+ +  L 
Sbjct: 1839 AIAIHWSSGDPGKGPITRYVIEARPSDEGLWDILIKDIPKE------VSSYTFS-MDILK 1891

Query: 969  PGVTYYFKVFAVSHGRESKPLTAQQT 994
            PGV+Y F+V AV+      P +  Q+
Sbjct: 1892 PGVSYDFRVIAVNDYGFGTPSSPSQS 1917



 Score = 72.8 bits (177), Expect = 4e-12
 Identities = 92/382 (24%), Positives = 153/382 (40%), Gaps = 47/382 (12%)

Query: 1643 VDVDSIKIAWESP---QGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYT 1699
            V+  +I + W  P      + RY +  S        L  + D +  +  ++GL P   Y 
Sbjct: 603  VERRAINLTWTKPFDGNSPLIRYILEMSENNAPWTVLLASVDPKATSVTVKGLVPARSYQ 662

Query: 1700 VSVVALHDDMESQPLIGTQSTAIPA------PTDLKFTQVTPTSLSAQWTPP-----NVQ 1748
              + A++D  + Q    T+  ++P       P ++  +  T  S+  QW PP     N  
Sbjct: 663  FRLCAVNDVGKGQFSKDTERVSLPEEPPTAPPQNVIASGRTNQSIMIQWQPPPESHQNGI 722

Query: 1749 LTGYRVRVTPKEKTGPMKEINLAP-DSSSVVVSGLMVATKYEVSVYALKDT--------L 1799
            L GY +R          +  N+   D +++++  L++ T YE+ V A            +
Sbjct: 723  LKGYIIRYCLAGLPVGYQFKNITDADVNNLLLEDLIIWTNYEIEVAAYNSAGLGVYSSKV 782

Query: 1800 TSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETIT-----GFQVDA-VPANG 1853
            T    QGV T      PP          TTI  +W   +         G+++ A  P   
Sbjct: 783  TEWTLQGVPTV-----PPGNVHAEATNSTTIRFTWNAPSPQFINGINQGYKLIAWEPEQE 837

Query: 1854 QTPIQRTIKPDVRSYT----ITGLQPGTDY---KIYLYTLNDNARSSPVVIDASTAIDAP 1906
            +     T +P+ +       ++GL+  T+Y    +   T  D  RS+P ++     +  P
Sbjct: 838  EEVTMVTARPNFQDSIHVGFVSGLKKFTEYFTSVLCFTTPGDGPRSTPQLVRTHEDVPGP 897

Query: 1907 -SNLRFLATTPNSLLVSWQPPRAR---ITGYIIKYEKPGSPPREVVPRPRPGVT-EATIT 1961
              +L F      SL VSWQ P  +   +TGY I +E+       V     P VT E  +T
Sbjct: 898  VGHLSFSEILDTSLKVSWQEPGEKNGILTGYRISWEEYNRTNTRVT-HYLPNVTLEYRVT 956

Query: 1962 GLEPGTEYTIYVIALKNNQKSE 1983
            GL   T YTI V A+ +  + +
Sbjct: 957  GLTALTTYTIEVAAMTSKGQGQ 978



 Score = 70.9 bits (172), Expect = 1e-11
 Identities = 111/557 (19%), Positives = 213/557 (38%), Gaps = 47/557 (8%)

Query: 1413 ITLTNLTPGTEYVVSIVALNGREESP--LLIGQQSTVSDVPRDLEVVAATPTSLL--ISW 1468
            I+ T+++    Y        G +E+   L++  ++ ++  P+D  V+  T  S++  ++ 
Sbjct: 462  ISPTHISDAGTYTCLATNSRGVDEASADLVVWARTRITKPPQDQSVIKGTQASMVCGVTH 521

Query: 1469 DAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSP 1528
            D P VT+RY     G T G        +  + S   IS    G   T T   ++  G+  
Sbjct: 522  D-PRVTIRYIWEKDGATLGTESHPRIRLDRNGSLH-ISQTWSGDIGTYTCRVISAGGNDS 579

Query: 1529 ASSKPISINYRTEIDKPSQMQVTDVQDNSISVKW---LPSSSPVTGYRVTTTPKNGPGPT 1585
             S+  + +       +     ++ V+  +I++ W      +SP+  Y +  +  N P   
Sbjct: 580  RSAH-LRVRQLPHAPEHPVATLSTVERRAINLTWTKPFDGNSPLIRYILEMSENNAPWTV 638

Query: 1586 KTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDR------PKGLA 1639
               +  P  T +T++GL P   Y   + A N  G+ Q    T   ++        P+ + 
Sbjct: 639  LLASVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSLPEEPPTAPPQNVI 698

Query: 1640 FTDVDVDSIKIAWESP-----QGQVSRYRVTYSSPEDGI-HELFPAPDGEEDTAELQGLR 1693
             +     SI I W+ P      G +  Y + Y      + ++     D + +   L+ L 
Sbjct: 699  ASGRTNQSIMIQWQPPPESHQNGILKGYIIRYCLAGLPVGYQFKNITDADVNNLLLEDLI 758

Query: 1694 PGSEYTVSVVALHD---DMESQPLIGTQSTAIPA--PTDLKFTQVTPTSLSAQWTPPNVQ 1748
              + Y + V A +     + S  +       +P   P ++       T++   W  P+ Q
Sbjct: 759  IWTNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNVHAEATNSTTIRFTWNAPSPQ 818

Query: 1749 L-----TGYRVRVTPKEKTGPMKEINLAPDSSSVV----VSGLMVATKYEVSVYALKDTL 1799
                   GY++     E+   +  +   P+    +    VSGL   T+Y  SV       
Sbjct: 819  FINGINQGYKLIAWEPEQEEEVTMVTARPNFQDSIHVGFVSGLKKFTEYFTSVLCFTTPG 878

Query: 1800 TS-RPAQGVVTTLENV-SPPRRARVTDATETTITISWR---TKTETITGFQVDAVPANGQ 1854
               R    +V T E+V  P      ++  +T++ +SW+    K   +TG+++     N  
Sbjct: 879  DGPRSTPQLVRTHEDVPGPVGHLSFSEILDTSLKVSWQEPGEKNGILTGYRISWEEYNRT 938

Query: 1855 TPIQRTIKPDVR-SYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAI-----DAPSN 1908
                    P+V   Y +TGL   T Y I +  +    +        S+ +       P+N
Sbjct: 939  NTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQVSASTISSGVPPELPGPPTN 998

Query: 1909 LRFLATTPNSLLVSWQP 1925
            L      P S+ + ++P
Sbjct: 999  LGISNIGPRSVTLQFRP 1015



 Score = 37.7 bits (86), Expect = 0.13
 Identities = 38/149 (25%), Positives = 59/149 (39%), Gaps = 20/149 (13%)

Query: 555  CDPVDQCQDSETGTFYQIGDSWEK---------YVHGVRYQCYCYGRGIGEWHCQPLQTY 605
            C PVD      T         W K         Y   +R + + YG  I       + T 
Sbjct: 1764 CSPVDGVSKIVTVDVKGNSPLWLKVKDLAEGVTYRFRIRAKTFTYGPEIEA----NVTTG 1819

Query: 606  PSSSGPVEVFITETPSQPNSHPIQWNAPQPSH--ISKYILRWRPKNSVGRWKEAT--IPG 661
            P    P    +       ++  I W++  P    I++Y++  RP +  G W      IP 
Sbjct: 1820 PGEGAPGPPGVPIIVRYSSAIAIHWSSGDPGKGPITRYVIEARPSDE-GLWDILIKDIPK 1878

Query: 662  HLNSYTIKG--LKPGVVYEGQLISIQQYG 688
             ++SYT     LKPGV Y+ ++I++  YG
Sbjct: 1879 EVSSYTFSMDILKPGVSYDFRVIAVNDYG 1907


>gi|157952215 protein tyrosine phosphatase, receptor type, B isoform a
            [Homo sapiens]
          Length = 2215

 Score =  164 bits (414), Expect = 1e-39
 Identities = 264/1284 (20%), Positives = 500/1284 (38%), Gaps = 106/1284 (8%)

Query: 668  IKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSES 727
            ++ L+ G +Y  ++IS+ +                       TV  +T P  P      S
Sbjct: 300  LQDLQAGTIYNFRIISLDE---------------------ERTVVLQTDPLPP-ARFGVS 337

Query: 728  VTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTAT--SVNIPDLLPGRK 785
              + T++S  V W  +S  V+ + V+    E   + Q + +  + +       +L  G K
Sbjct: 338  KEKTTSTSLHVWWTPSSGKVTSYEVQL-FDENNQKIQGVQIQESTSWNEYTFFNLTAGSK 396

Query: 786  YIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVY 845
            Y + +  +S  G++S  + T+ +T P    D  +      S+++ WS     +  YR++ 
Sbjct: 397  YNIAITAVS-GGKRSFSVYTNGSTVPSPVKDIGIS-TKANSLLISWSHGSGNVERYRLML 454

Query: 846  SPS---VEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTP 902
                  V G   + +    A S     L PG  YN+T+       ++    + +      
Sbjct: 455  MDKGILVHGGVVDKH----ATSYAFHGLTPGYLYNLTVMTEAAGLQNYRWKLVRT----- 505

Query: 903  RSDTVPSPRDLQFVEVTD----VKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLP-IS 957
                  +P ++  ++VT+      + + W  P   V  Y + +       E     P I+
Sbjct: 506  ------APMEVSNLKVTNDGSLTSLKVKWQRPPGNVDSYNITLSHKGTIKESRVLAPWIT 559

Query: 958  RNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDS-TVLVR 1016
               F E   L PG  Y   V  VS G  S    A   T  D   NL+  N     +++V 
Sbjct: 560  ETHFKE---LVPGRLYQVTVSCVS-GELSAQKMAVGRTFPDKVANLEANNNGRMRSLVVS 615

Query: 1017 WTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRN--LQPASEYTVSLVAIKGNQE 1074
            W+PP      YR+ +            VG   ++Y + +  L P  +Y V ++   GN +
Sbjct: 616  WSPPAGDWEQYRILL-FNDSVVLLNITVGKEETQYVMDDTGLVPGRQYEVEVIVESGNLK 674

Query: 1075 SPKATGVFTTLQPGSSIPPYNTEVTETTIVITW-TP-APRIGFKLGVRPSQGGEAPREVT 1132
            + +     T   P + +        ET++ I W TP A    + + +         + ++
Sbjct: 675  NSERCQGRTV--PLAVLQLRVKHANETSLSIMWQTPVAEWEKYIISLADRDLLLIHKSLS 732

Query: 1133 SDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLT 1192
             D+     + L PG +Y+ T+  +    +  + +  + V   +  T+LH+     T  L 
Sbjct: 733  KDAKEFTFTDLVPGRKYMATVTSISGDLKNSSSVKGRTVP--AQVTDLHVANQGMTSSLF 790

Query: 1193 VSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKD 1252
             +W ++   D+  Y++     N    N   E + ++ S  +F +L  G  Y+V V TV  
Sbjct: 791  TNWTQAQG-DVEFYQVLLIHENVVIKN---ESISSETSRYSFHSLKSGSLYSVVVTTVSG 846

Query: 1253 DKES--VPISDTIIPAVPPPTDLRFTNIGP-DTMRVTWAPPPSIDLTNFLVRYSPVKNEE 1309
               S  V +    +P+    + +   N G  D + V+W   P  D+ N+ V  S   + +
Sbjct: 847  GISSRQVVVEGRTVPS--SVSGVTVNNSGRNDYLSVSWLLAPG-DVDNYEVTLS--HDGK 901

Query: 1310 DVAELSISPSDNAVVLTNLLPGTEYVVSV---SSVYEQHESTPLRGRQKTGLDSPTGIDF 1366
             V  L I+ S      ++L PG  Y V++   S  YE H  +    +++T  D   G+  
Sbjct: 902  VVQSLVIAKSVRECSFSSLTPGRLYTVTITTRSGKYENHSFS----QERTVPDKVQGVSV 957

Query: 1367 SDITANSFT-VHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYV 1425
            S+   + +  V W+        Y +    ++   + +   +P S N      L PG  Y 
Sbjct: 958  SNSARSDYLRVSWVHATGDFDHYEVTIKNKNNFIQTKS--IPKSENECVFVQLVPGRLYS 1015

Query: 1426 VSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRIT--YG 1483
            V++   +G+ E+    G   T+ +  +DL +   +   L ++W      V  Y I   + 
Sbjct: 1016 VTVTTKSGQYEANEQ-GNGRTIPEPVKDLTLRNRSTEDLHVTWSGANGDVDQYEIQLLFN 1074

Query: 1484 ETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEID 1543
            +     P   F +  + +    + L PG  Y I V  ++G     A  +  ++    +  
Sbjct: 1075 DMKVFPP---FHLVNTATEYRFTSLTPGRQYKILVLTISGDVQQSAFIEGFTVPSAVKNI 1131

Query: 1544 KPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQ 1603
              S    TD    S++V W P    V  Y V+    +      ++T      E T   L+
Sbjct: 1132 HISPNGATD----SLTVNWTPGGGDVDSYTVSAFRHSQK--VDSQTIPKHVFEHTFHRLE 1185

Query: 1604 PTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYR 1663
               +Y + + + + S ++Q  V            +A       S+ ++W+   G   RY 
Sbjct: 1186 AGEQYQIMIASVSGSLKNQINVVGRTVPASVQGVIADNAYSSYSLIVSWQKAAGVAERYD 1245

Query: 1664 VTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIP 1723
            +   + E+GI     +        + + L PG +Y + ++ +   + S+       T   
Sbjct: 1246 ILLLT-ENGILLRNTSEPATTKQHKFEDLTPGKKYKIQILTVSGGLFSKEAQTEGRTVPA 1304

Query: 1724 APTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKE-INLAPDSSSVVVSGL 1782
            A TDL+ T+ +   LS +WT    +L+ Y + +   +  G ++E   + P   S     L
Sbjct: 1305 AVTDLRITENSTRHLSFRWTASEGELSWYNIFLYNPD--GNLQERAQVDPLVQSFSFQNL 1362

Query: 1783 MVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETIT 1842
            +    Y++ +      L++       T   +VS  R +     T  ++  +W   +    
Sbjct: 1363 LQGRMYKMVIVTHSGELSNESFIFGRTVPASVSHLRGSNRN--TTDSLWFNWSPASGDFD 1420

Query: 1843 GFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTA 1902
             +++     NG T  +     D+  +   GL PG  Y +++ T +    S+ V  ++ TA
Sbjct: 1421 FYELILYNPNG-TKKENWKDKDLTEWRFQGLVPGRKYVLWVVT-HSGDLSNKVTAESRTA 1478

Query: 1903 IDAPSNLRFLATTPNSLLVSWQPP 1926
               PS + F      SL ++W+ P
Sbjct: 1479 PSPPSLMSFADIANTSLAITWKGP 1502



 Score =  154 bits (389), Expect = 1e-36
 Identities = 268/1271 (21%), Positives = 471/1271 (37%), Gaps = 99/1271 (7%)

Query: 662  HLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPL 721
            H  SY   GL PG +Y   L  + +    +  R+    T                  +P+
Sbjct: 469  HATSYAFHGLTPGYLY--NLTVMTEAAGLQNYRWKLVRT------------------APM 508

Query: 722  VATSESVT-EITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL 780
              ++  VT + + +S  V W      V  + +   LS +G   +   L    T  +  +L
Sbjct: 509  EVSNLKVTNDGSLTSLKVKWQRPPGNVDSYNI--TLSHKGTIKESRVLAPWITETHFKEL 566

Query: 781  LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDD-TSIVVRWSRPQAPIT 839
            +PGR Y V V  +S  GE S        T PD   +   +      S+VV WS P     
Sbjct: 567  VPGRLYQVTVSCVS--GELSAQKMAVGRTFPDKVANLEANNNGRMRSLVVSWSPPAGDWE 624

Query: 840  GYRI-VYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQET 898
             YRI +++ SV   +  +   ET   +  + L PG QY + +     N +++        
Sbjct: 625  QYRILLFNDSVVLLNITVGKEETQYVMDDTGLVPGRQYEVEVIVESGNLKNSE------- 677

Query: 899  TGTPRSDTVP-SPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPIS 957
                +  TVP +   L+     +  ++IMW  P +    Y + +   +L   H + L   
Sbjct: 678  --RCQGRTVPLAVLQLRVKHANETSLSIMWQTPVAEWEKYIISLADRDLLLIH-KSLSKD 734

Query: 958  RNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNE-TDSTVLVR 1016
               F   T L PG  Y   V ++S   ++      +T      T+L   N+   S++   
Sbjct: 735  AKEFT-FTDLVPGRKYMATVTSISGDLKNSSSVKGRTVPAQV-TDLHVANQGMTSSLFTN 792

Query: 1017 WTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESP 1076
            WT  +  +  Y++ + +      +  ++    S+Y   +L+  S Y+V +  + G   S 
Sbjct: 793  WTQAQGDVEFYQVLL-IHENVVIKNESISSETSRYSFHSLKSGSLYSVVVTTVSGGISSR 851

Query: 1077 KATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPRE--VTSD 1134
            +      T+    S    N       + ++W  AP       V  S  G+  +   +   
Sbjct: 852  QVVVEGRTVPSSVSGVTVNNSGRNDYLSVSWLLAPGDVDNYEVTLSHDGKVVQSLVIAKS 911

Query: 1135 SGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVS 1194
                  S LTPG  Y  TI       E  +    + V       ++   A  D   L VS
Sbjct: 912  VRECSFSSLTPGRLYTVTITTRSGKYENHSFSQERTVPDKVQGVSVSNSARSD--YLRVS 969

Query: 1195 WERSTTPDITGYRITTTPTNGQQGNSLE-EVVHADQSSCTFDNLSPGLEYNVSVYTVKDD 1253
            W  + T D   Y +T    N    N ++ + +   ++ C F  L PG  Y+V+V T    
Sbjct: 970  WVHA-TGDFDHYEVTIKNKN----NFIQTKSIPKSENECVFVQLVPGRLYSVTVTTKSGQ 1024

Query: 1254 KESVPISD-TIIPAVPPPTDLRFTNIGPDTMRVTWA-PPPSIDLTNFLVRYSPVKNEEDV 1311
             E+    +   IP   P  DL   N   + + VTW+     +D     + ++ +K     
Sbjct: 1025 YEANEQGNGRTIP--EPVKDLTLRNRSTEDLHVTWSGANGDVDQYEIQLLFNDMK---VF 1079

Query: 1312 AELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITA 1371
                +  +      T+L PG +Y + V ++    + +        G   P+ +    I+ 
Sbjct: 1080 PPFHLVNTATEYRFTSLTPGRQYKILVLTISGDVQQSAF----IEGFTVPSAVKNIHISP 1135

Query: 1372 N----SFTVHWIAPRATITGYRI---RHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEY 1424
            N    S TV+W      +  Y +   RH     S +     +P      T   L  G +Y
Sbjct: 1136 NGATDSLTVNWTPGGGDVDSYTVSAFRH-----SQKVDSQTIPKHVFEHTFHRLEAGEQY 1190

Query: 1425 VVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWD-APAVTVRYYRITYG 1483
             + I +++G  ++ + +  ++  + V   +   A +  SL++SW  A  V  RY  +   
Sbjct: 1191 QIMIASVSGSLKNQINVVGRTVPASVQGVIADNAYSSYSLIVSWQKAAGVAERYDILLLT 1250

Query: 1484 ETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEID 1543
            E G    ++  + P +        L PG  Y I +  V+G       SK      RT   
Sbjct: 1251 ENG--ILLRNTSEPATTKQHKFEDLTPGKKYKIQILTVSG----GLFSKEAQTEGRTVPA 1304

Query: 1544 KPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQ 1603
              + +++T+     +S +W  S   ++ Y +     +G    + +     Q+      LQ
Sbjct: 1305 AVTDLRITENSTRHLSFRWTASEGELSWYNIFLYNPDGNLQERAQVDPLVQSFSFQNLLQ 1364

Query: 1604 PTV-EYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRY 1662
              + + V+  ++   S ES    +T   ++   +G        DS+   W    G    Y
Sbjct: 1365 GRMYKMVIVTHSGELSNESFIFGRTVPASVSHLRG--SNRNTTDSLWFNWSPASGDFDFY 1422

Query: 1663 RVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAI 1722
             +   +P     E +   D  E     QGL PG +Y + VV    D+ ++  +  +S   
Sbjct: 1423 ELILYNPNGTKKENWKDKDLTE--WRFQGLVPGRKYVLWVVTHSGDLSNK--VTAESRTA 1478

Query: 1723 PAPTDL-KFTQVTPTSLSAQWT-PPN-VQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVV 1779
            P+P  L  F  +  TSL+  W  PP+      + ++  P++        N    S   +V
Sbjct: 1479 PSPPSLMSFADIANTSLAITWKGPPDWTDYNDFELQWLPRDALTVFNPYN-NRKSEGRIV 1537

Query: 1780 SGLMVATKYEVSVYALKD---TLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRT 1836
             GL     Y+ +V  +        S+P  G V T  +       R  ++  T I  SW  
Sbjct: 1538 YGLRPGRSYQFNVKTVSGDSWKTYSKPIFGSVRTKPDKIQNLHCRPQNS--TAIACSWIP 1595

Query: 1837 KTETITGFQVDAVPANGQ-TPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPV 1895
                  G+ ++    + Q     R ++ +     I  L P   Y + +   +    S  V
Sbjct: 1596 PDSDFDGYSIECRKMDTQEVEFSRKLEKEKSLLNIMMLVPHKRYLVSIKVQSAGMTSEVV 1655

Query: 1896 VIDASTAIDAP 1906
                 T ID P
Sbjct: 1656 EDSTITMIDRP 1666



 Score =  150 bits (379), Expect = 1e-35
 Identities = 272/1321 (20%), Positives = 506/1321 (38%), Gaps = 92/1321 (6%)

Query: 693  TRFDFTTTSTSTPVTSNTV--TGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGF 750
            ++++   T+ S    S +V   G T P SP+     S     A+S ++SW   S  V  +
Sbjct: 395  SKYNIAITAVSGGKRSFSVYTNGSTVP-SPVKDIGISTK---ANSLLISWSHGSGNVERY 450

Query: 751  RVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISED-GEQSLILSTSQTT 809
            R+   L ++G       +   ATS     L PG  Y+ N+  ++E  G Q+      +T 
Sbjct: 451  RLM--LMDKGILVHGGVVDKHATSYAFHGLTPG--YLYNLTVMTEAAGLQNYRWKLVRTA 506

Query: 810  APDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSD 869
              +       +    TS+ V+W RP   +  Y I  S       + +  P    +    +
Sbjct: 507  PMEVSNLKVTNDGSLTSLKVKWQRPPGNVDSYNITLSHKGTIKESRVLAPWITET-HFKE 565

Query: 870  LQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTP 929
            L PG  Y +T+  V     S  +  Q+   G    D V +        +  + V+  W+P
Sbjct: 566  LVPGRLYQVTVSCV-----SGELSAQKMAVGRTFPDKVANLEANNNGRMRSLVVS--WSP 618

Query: 930  PESAVTGYRV-----DVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGR 984
            P      YR+      V+ +N+     +   +  +T     GL PG  Y  +V   S   
Sbjct: 619  PAGDWEQYRILLFNDSVVLLNITVGKEETQYVMDDT-----GLVPGRQYEVEVIVESGNL 673

Query: 985  ESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNV 1044
            ++      +T  L A   L+  +  ++++ + W  P A+   Y +++   R       ++
Sbjct: 674  KNSERCQGRTVPL-AVLQLRVKHANETSLSIMWQTPVAEWEKYIISLA-DRDLLLIHKSL 731

Query: 1045 GPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIV 1104
                 ++   +L P  +Y  ++ +I G+ ++  +    T     + +   N  +T +++ 
Sbjct: 732  SKDAKEFTFTDLVPGRKYMATVTSISGDLKNSSSVKGRTVPAQVTDLHVANQGMT-SSLF 790

Query: 1105 ITWTPAPR-IGFKLGVRPSQGGEAPRE-VTSDSGSIVVSGLTPGVEYVYTIQVLRDGQER 1162
              WT A   + F   +   +      E ++S++       L  G  Y   +  +  G   
Sbjct: 791  TNWTQAQGDVEFYQVLLIHENVVIKNESISSETSRYSFHSLKSGSLYSVVVTTVSGGISS 850

Query: 1163 DAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLE 1222
               +V     P S  + + +  +     L+VSW  +   D+  Y +T +  +G+   SL 
Sbjct: 851  RQVVVEGRTVP-SSVSGVTVNNSGRNDYLSVSWLLAPG-DVDNYEVTLSH-DGKVVQSL- 906

Query: 1223 EVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS-DTIIPAVPPPTDLRFTNIGPD 1281
             V+      C+F +L+PG  Y V++ T     E+   S +  +P       +   +   D
Sbjct: 907  -VIAKSVRECSFSSLTPGRLYTVTITTRSGKYENHSFSQERTVPDKVQGVSVS-NSARSD 964

Query: 1282 TMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAEL-SISPSDNAVVLTNLLPGTEYVVSVSS 1340
             +RV+W      D  ++ V    +KN+ +  +  SI  S+N  V   L+PG  Y V+V++
Sbjct: 965  YLRVSWVHATG-DFDHYEVT---IKNKNNFIQTKSIPKSENECVFVQLVPGRLYSVTVTT 1020

Query: 1341 VYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGR 1400
               Q+E+   +G  +T  +    +   + +     V W      +  Y I+         
Sbjct: 1021 KSGQYEANE-QGNGRTIPEPVKDLTLRNRSTEDLHVTWSGANGDVDQYEIQLLFNDMKVF 1079

Query: 1401 PREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAAT 1460
            P    V ++      T+LTPG +Y + ++ ++G  +    I +  TV    +++ +    
Sbjct: 1080 PPFHLV-NTATEYRFTSLTPGRQYKILVLTISGDVQQSAFI-EGFTVPSAVKNIHISPNG 1137

Query: 1461 PT-SLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVY 1519
             T SL ++W      V  Y  T      +  V   T+P      T   L+ G  Y I + 
Sbjct: 1138 ATDSLTVNWTPGGGDVDSY--TVSAFRHSQKVDSQTIPKHVFEHTFHRLEAGEQYQIMIA 1195

Query: 1520 AVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSIS-----VKWLPSSSPVTGYRV 1574
            +V+G     +    I++  RT    P+ +Q   + DN+ S     V W  ++     Y +
Sbjct: 1196 SVSG-----SLKNQINVVGRTV---PASVQGV-IADNAYSSYSLIVSWQKAAGVAERYDI 1246

Query: 1575 TTTPKNGPGPTKTKTAGPDQTEM-TIEGLQPTVEYVVSVYAQNP---SGESQP---LVQT 1627
                +NG       T+ P  T+    E L P  +Y + +   +    S E+Q     V  
Sbjct: 1247 LLLTENGI--LLRNTSEPATTKQHKFEDLTPGKKYKIQILTVSGGLFSKEAQTEGRTVPA 1304

Query: 1628 AVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTA 1687
            AVT+      L  T+     +   W + +G++S Y +   +P+  + E     D    + 
Sbjct: 1305 AVTD------LRITENSTRHLSFRWTASEGELSWYNIFLYNPDGNLQERAQV-DPLVQSF 1357

Query: 1688 ELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNV 1747
              Q L  G  Y + +V    ++ ++  I  ++            + T  SL   W+P + 
Sbjct: 1358 SFQNLLQGRMYKMVIVTHSGELSNESFIFGRTVPASVSHLRGSNRNTTDSLWFNWSPASG 1417

Query: 1748 QLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGV 1807
                Y + +      G  KE     D +     GL+   KY + V      L+++     
Sbjct: 1418 DFDFYELILY--NPNGTKKENWKDKDLTEWRFQGLVPGRKYVLWVVTHSGDLSNKVTAES 1475

Query: 1808 VTTLENVSPPRRARVTDATETTITISWRTKTE--TITGFQVDAVPANGQTPIQRTIKPDV 1865
             T     SPP      D   T++ I+W+   +      F++  +P +  T          
Sbjct: 1476 RTA---PSPPSLMSFADIANTSLAITWKGPPDWTDYNDFELQWLPRDALTVFNPYNNRKS 1532

Query: 1866 RSYTITGLQPGTDYKIYLYTLNDNA---RSSPVVIDASTAIDAPSNLRFLATTPNSLLVS 1922
                + GL+PG  Y+  + T++ ++    S P+     T  D   NL        ++  S
Sbjct: 1533 EGRIVYGLRPGRSYQFNVKTVSGDSWKTYSKPIFGSVRTKPDKIQNLHCRPQNSTAIACS 1592

Query: 1923 WQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKS 1982
            W PP +   GY I+  K  +   E   +     +   I  L P   Y + +        S
Sbjct: 1593 WIPPDSDFDGYSIECRKMDTQEVEFSRKLEKEKSLLNIMMLVPHKRYLVSIKVQSAGMTS 1652

Query: 1983 E 1983
            E
Sbjct: 1653 E 1653



 Score =  142 bits (357), Expect = 5e-33
 Identities = 249/1241 (20%), Positives = 467/1241 (37%), Gaps = 126/1241 (10%)

Query: 798  EQSLILSTSQ----TTAPDAPPDP-------TVDQVDDTSIVVRWSRPQAPITGYRIVYS 846
            + S +LST+Q    TT      +P          +    S+ ++W    +P   + ++YS
Sbjct: 219  DTSWVLSTTQPFSSTTEETGLAEPERCNFTLAESKASSHSVSIQWRILGSPCN-FSLIYS 277

Query: 847  PSVEGSST--ELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRS 904
                G++      +  T     L DLQ G  YN  I +++E           E T   ++
Sbjct: 278  SDTLGAALCPTFRIDNTTYGCNLQDLQAGTIYNFRIISLDE-----------ERTVVLQT 326

Query: 905  DTVPSPR-DLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAE 963
            D +P  R  +   + T   + + WTP    VT Y V +   N     G ++  S  ++ E
Sbjct: 327  DPLPPARFGVSKEKTTSTSLHVWWTPSSGKVTSYEVQLFDENNQKIQGVQIQES-TSWNE 385

Query: 964  VT--GLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPR 1021
             T   L+ G  Y   + AVS G+ S  +    +T + +P     ++   +++L+ W+   
Sbjct: 386  YTFFNLTAGSKYNIAITAVSGGKRSFSVYTNGST-VPSPVKDIGISTKANSLLISWSHGS 444

Query: 1022 AQITGYRLTV---GLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKA 1078
              +  YRL +   G+   G      V    + Y    L P   Y ++++      ++ + 
Sbjct: 445  GNVERYRLMLMDKGILVHGGV----VDKHATSYAFHGLTPGYLYNLTVMTEAAGLQNYRW 500

Query: 1079 TGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGG--EAPREVTSDSG 1136
              V T     S++   N + + T++ + W   P       +  S  G  +  R +     
Sbjct: 501  KLVRTAPMEVSNLKVTN-DGSLTSLKVKWQRPPGNVDSYNITLSHKGTIKESRVLAPWIT 559

Query: 1137 SIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGV--LTVS 1194
                  L PG  Y  T+  +          V +      P    +LEAN +  +  L VS
Sbjct: 560  ETHFKELVPGRLYQVTVSCVSGELSAQKMAVGRTF----PDKVANLEANNNGRMRSLVVS 615

Query: 1195 WERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDN--LSPGLEYNVSVYTVKD 1252
            W      D   YRI            L   V  +++    D+  L PG +Y V V     
Sbjct: 616  WS-PPAGDWEQYRILLF---NDSVVLLNITVGKEETQYVMDDTGLVPGRQYEVEVIVESG 671

Query: 1253 D-KESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDV 1311
            + K S       +P       LR  +    ++ + W  P + +   +++  S    +  +
Sbjct: 672  NLKNSERCQGRTVPLA--VLQLRVKHANETSLSIMWQTPVA-EWEKYII--SLADRDLLL 726

Query: 1312 AELSISPSDNAVVLTNLLPGTEYVVSVSSVY-EQHESTPLRGRQKTGLDSPTGIDFSDIT 1370
               S+S        T+L+PG +Y+ +V+S+  +   S+ ++GR      +   +    +T
Sbjct: 727  IHKSLSKDAKEFTFTDLVPGRKYMATVTSISGDLKNSSSVKGRTVPAQVTDLHVANQGMT 786

Query: 1371 ANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVA 1430
            ++ FT +W   +  +  Y++    E+     + + +    +  +  +L  G+ Y V +  
Sbjct: 787  SSLFT-NWTQAQGDVEFYQVLLIHENVV--IKNESISSETSRYSFHSLKSGSLYSVVVTT 843

Query: 1431 LNGREESPLLIGQQSTVSDVPRDLEVVAATPTS----LLISWDAPAVTVRYYRITYGETG 1486
            ++G   S  ++ +  T   VP  +  V    +     L +SW      V  Y +T    G
Sbjct: 844  VSGGISSRQVVVEGRT---VPSSVSGVTVNNSGRNDYLSVSWLLAPGDVDNYEVTLSHDG 900

Query: 1487 GNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPS 1546
                VQ   +  S    + S L PG  YT+T+   +G+ ++ + S+      RT  DK  
Sbjct: 901  --KVVQSLVIAKSVRECSFSSLTPGRLYTVTITTRSGKYENHSFSQE-----RTVPDKVQ 953

Query: 1547 QMQVTD-VQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPT 1605
             + V++  + + + V W+ ++     Y VT   KN     +TK+    + E     L P 
Sbjct: 954  GVSVSNSARSDYLRVSWVHATGDFDHYEVTIKNKN--NFIQTKSIPKSENECVFVQLVPG 1011

Query: 1606 VEYVVSVYAQNPSGESQPLVQTAVTNIDRP-KGLAFTDVDVDSIKIAWESPQGQVSRYRV 1664
              Y V+V  +  SG+ +   Q     I  P K L   +   + + + W    G V +Y +
Sbjct: 1012 RLYSVTVTTK--SGQYEANEQGNGRTIPEPVKDLTLRNRSTEDLHVTWSGANGDVDQYEI 1069

Query: 1665 TYSSPEDGIHELFPAPDGEEDTA---ELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTA 1721
                 +    ++FP P    +TA       L PG +Y + V+ +  D++    I      
Sbjct: 1070 QLLFND---MKVFP-PFHLVNTATEYRFTSLTPGRQYKILVLTISGDVQQSAFI----EG 1121

Query: 1722 IPAPTDLKFTQVTPT----SLSAQWTPPNVQLTGYRV-----------RVTPKEKTGPMK 1766
               P+ +K   ++P     SL+  WTP    +  Y V           +  PK       
Sbjct: 1122 FTVPSAVKNIHISPNGATDSLTVNWTPGGGDVDSYTVSAFRHSQKVDSQTIPKHVFEHTF 1181

Query: 1767 EINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDAT 1826
                A +   ++++ +  + K +++V            QGV+                 +
Sbjct: 1182 HRLEAGEQYQIMIASVSGSLKNQINVVG---RTVPASVQGVIAD------------NAYS 1226

Query: 1827 ETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKP-DVRSYTITGLQPGTDYKIYLYT 1885
              ++ +SW+        + +  +  NG   ++ T +P   + +    L PG  YKI + T
Sbjct: 1227 SYSLIVSWQKAAGVAERYDILLLTENG-ILLRNTSEPATTKQHKFEDLTPGKKYKIQILT 1285

Query: 1886 LNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPR 1945
            ++    S     +  T   A ++LR    +   L   W      ++ Y I    P    +
Sbjct: 1286 VSGGLFSKEAQTEGRTVPAAVTDLRITENSTRHLSFRWTASEGELSWYNIFLYNPDGNLQ 1345

Query: 1946 EVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLI 1986
            E   +  P V   +   L  G  Y + ++       +E  I
Sbjct: 1346 ERA-QVDPLVQSFSFQNLLQGRMYKMVIVTHSGELSNESFI 1385



 Score =  102 bits (255), Expect = 3e-21
 Identities = 218/1016 (21%), Positives = 374/1016 (36%), Gaps = 81/1016 (7%)

Query: 698  TTTSTSTPV-TSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYEL 756
            T TS S  +  S++V G T P    V       +   SS   +W  A   V  ++V   L
Sbjct: 752  TVTSISGDLKNSSSVKGRTVPAQ--VTDLHVANQGMTSSLFTNWTQAQGDVEFYQVL--L 807

Query: 757  SEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPD 816
              E    +   + S  +  +   L  G  Y V V  +S  G  S  +     T P +   
Sbjct: 808  IHENVVIKNESISSETSRYSFHSLKSGSLYSVVVTTVS-GGISSRQVVVEGRTVPSSVSG 866

Query: 817  PTVDQVDDTSIV-VRWSRPQAPITGYRIVYSPSVEGSSTE-LNLPETANSVTLSDLQPGV 874
             TV+       + V W      +  Y +  S   +G   + L + ++    + S L PG 
Sbjct: 867  VTVNNSGRNDYLSVSWLLAPGDVDNYEVTLSH--DGKVVQSLVIAKSVRECSFSSLTPGR 924

Query: 875  QYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVK----VTIMWTPP 930
             Y +TI       E+      QE T          P  +Q V V++      + + W   
Sbjct: 925  LYTVTITTRSGKYENHS--FSQERT---------VPDKVQGVSVSNSARSDYLRVSWVHA 973

Query: 931  ESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLT 990
                  Y V +   N      + +P S N    V  L PG  Y   V   S   E+    
Sbjct: 974  TGDFDHYEVTIKNKN-NFIQTKSIPKSENECVFVQ-LVPGRLYSVTVTTKSGQYEANEQG 1031

Query: 991  AQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSK 1050
              +T   +   +L   N +   + V W+     +  Y + +          +++  + ++
Sbjct: 1032 NGRTIP-EPVKDLTLRNRSTEDLHVTWSGANGDVDQYEIQLLFNDMKVFPPFHLVNTATE 1090

Query: 1051 YPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPA 1110
            Y   +L P  +Y + ++ I G+ +       FT      +I       T++ + + WTP 
Sbjct: 1091 YRFTSLTPGRQYKILVLTISGDVQQSAFIEGFTVPSAVKNIHISPNGATDS-LTVNWTPG 1149

Query: 1111 PRIGFKLGV---RPSQGGEA---PREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDA 1164
                    V   R SQ  ++   P+ V   +       L  G +Y   I  +    +   
Sbjct: 1150 GGDVDSYTVSAFRHSQKVDSQTIPKHVFEHT----FHRLEAGEQYQIMIASVSGSLKNQI 1205

Query: 1165 PIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEV 1224
             +V + V P S    +   A     ++ VSW+++       Y I     NG    +  E 
Sbjct: 1206 NVVGRTV-PASVQGVIADNAYSSYSLI-VSWQKAAGV-AERYDILLLTENGILLRNTSEP 1262

Query: 1225 VHADQSSCTFDNLSPGLEYNVSVYTVKD---DKESVPISDTIIPAVPPPTDLRFTNIGPD 1281
                Q    F++L+PG +Y + + TV      KE+     T+  AV   TDLR T     
Sbjct: 1263 ATTKQHK--FEDLTPGKKYKIQILTVSGGLFSKEAQTEGRTVPAAV---TDLRITENSTR 1317

Query: 1282 TMRVTW-APPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEY-VVSVS 1339
             +   W A    +   N  + Y+P  N ++ A+  + P   +    NLL G  Y +V V+
Sbjct: 1318 HLSFRWTASEGELSWYNIFL-YNPDGNLQERAQ--VDPLVQSFSFQNLLQGRMYKMVIVT 1374

Query: 1340 SVYEQHESTPLRGRQ-KTGLDSPTGIDFSDITANSFTVHWIAPRATITGYR-IRHHPEHF 1397
               E    + + GR     +    G + +  T +S   +W         Y  I ++P   
Sbjct: 1375 HSGELSNESFIFGRTVPASVSHLRGSNRN--TTDSLWFNWSPASGDFDFYELILYNP--- 1429

Query: 1398 SGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVV 1457
            +G  +E+             L PG +YV+ +V  +G + S  +  +  T    P  +   
Sbjct: 1430 NGTKKENWKDKDLTEWRFQGLVPGRKYVLWVVTHSG-DLSNKVTAESRTAPSPPSLMSFA 1488

Query: 1458 AATPTSLLISWDAPAVTVRY--YRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYT 1515
                TSL I+W  P     Y  + + +      +    +    S+    + GL+PG  Y 
Sbjct: 1489 DIANTSLAITWKGPPDWTDYNDFELQWLPRDALTVFNPYNNRKSEGRI-VYGLRPGRSYQ 1547

Query: 1516 ITVYAVTGRGDS-PASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRV 1574
              V  V+G  DS    SKPI  + RT+ DK   +        +I+  W+P  S   GY +
Sbjct: 1548 FNVKTVSG--DSWKTYSKPIFGSVRTKPDKIQNLHCRPQNSTAIACSWIPPDSDFDGYSI 1605

Query: 1575 TTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDR 1634
                 +      ++    +++ + I  L P   Y+VS+  Q+    S+ +  + +T IDR
Sbjct: 1606 ECRKMDTQEVEFSRKLEKEKSLLNIMMLVPHKRYLVSIKVQSAGMTSEVVEDSTITMIDR 1665

Query: 1635 P-----------KGLAFTDVDVD-SIKIAWESPQGQVSRYRVTYSSPEDGIHELFP 1678
            P           K +  +   ++ ++  +W S      +Y        DG  EL P
Sbjct: 1666 PPPPPPHIRVNEKDVLISKSSINFTVNCSWFSDTNGAVKYFTVVVREADGSDELKP 1721



 Score = 35.8 bits (81), Expect = 0.50
 Identities = 32/136 (23%), Positives = 57/136 (41%), Gaps = 6/136 (4%)

Query: 1860 TIKPDVRSY--TITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPN 1917
            T + D  +Y   +  LQ GT Y   + +L++      VV+       A   +    TT  
Sbjct: 288  TFRIDNTTYGCNLQDLQAGTIYNFRIISLDEERT---VVLQTDPLPPARFGVSKEKTTST 344

Query: 1918 SLLVSWQPPRARITGYIIK-YEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIAL 1976
            SL V W P   ++T Y ++ +++     + V  +      E T   L  G++Y I + A+
Sbjct: 345  SLHVWWTPSSGKVTSYEVQLFDENNQKIQGVQIQESTSWNEYTFFNLTAGSKYNIAITAV 404

Query: 1977 KNNQKSEPLIGRKKTV 1992
               ++S  +     TV
Sbjct: 405  SGGKRSFSVYTNGSTV 420



 Score = 35.4 bits (80), Expect = 0.66
 Identities = 37/194 (19%), Positives = 76/194 (39%), Gaps = 25/194 (12%)

Query: 628  IQWNAPQP-SHISKYILRWRPKNSV---GRWKEATIPGHLNSYTIKGLKPGVVYEGQLIS 683
            I W  P   +  + + L+W P++++     +      G +    + GL+PG  Y+  + +
Sbjct: 1497 ITWKGPPDWTDYNDFELQWLPRDALTVFNPYNNRKSEGRI----VYGLRPGRSYQFNVKT 1552

Query: 684  IQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSA 743
            +     +  ++  F +  T      N           L    ++ T I  S     W+  
Sbjct: 1553 VSGDSWKTYSKPIFGSVRTKPDKIQN-----------LHCRPQNSTAIACS-----WIPP 1596

Query: 744  SDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLIL 803
                 G+ +E    +  +      L    + +NI  L+P ++Y+V++ ++   G  S ++
Sbjct: 1597 DSDFDGYSIECRKMDTQEVEFSRKLEKEKSLLNIMMLVPHKRYLVSI-KVQSAGMTSEVV 1655

Query: 804  STSQTTAPDAPPDP 817
              S  T  D PP P
Sbjct: 1656 EDSTITMIDRPPPP 1669


>gi|157952213 protein tyrosine phosphatase, receptor type, B isoform b
            precursor [Homo sapiens]
          Length = 1997

 Score =  164 bits (414), Expect = 1e-39
 Identities = 264/1284 (20%), Positives = 500/1284 (38%), Gaps = 106/1284 (8%)

Query: 668  IKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSES 727
            ++ L+ G +Y  ++IS+ +                       TV  +T P  P      S
Sbjct: 82   LQDLQAGTIYNFRIISLDE---------------------ERTVVLQTDPLPP-ARFGVS 119

Query: 728  VTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTAT--SVNIPDLLPGRK 785
              + T++S  V W  +S  V+ + V+    E   + Q + +  + +       +L  G K
Sbjct: 120  KEKTTSTSLHVWWTPSSGKVTSYEVQL-FDENNQKIQGVQIQESTSWNEYTFFNLTAGSK 178

Query: 786  YIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVY 845
            Y + +  +S  G++S  + T+ +T P    D  +      S+++ WS     +  YR++ 
Sbjct: 179  YNIAITAVS-GGKRSFSVYTNGSTVPSPVKDIGIS-TKANSLLISWSHGSGNVERYRLML 236

Query: 846  SPS---VEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTP 902
                  V G   + +    A S     L PG  YN+T+       ++    + +      
Sbjct: 237  MDKGILVHGGVVDKH----ATSYAFHGLTPGYLYNLTVMTEAAGLQNYRWKLVRT----- 287

Query: 903  RSDTVPSPRDLQFVEVTD----VKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLP-IS 957
                  +P ++  ++VT+      + + W  P   V  Y + +       E     P I+
Sbjct: 288  ------APMEVSNLKVTNDGSLTSLKVKWQRPPGNVDSYNITLSHKGTIKESRVLAPWIT 341

Query: 958  RNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDS-TVLVR 1016
               F E   L PG  Y   V  VS G  S    A   T  D   NL+  N     +++V 
Sbjct: 342  ETHFKE---LVPGRLYQVTVSCVS-GELSAQKMAVGRTFPDKVANLEANNNGRMRSLVVS 397

Query: 1017 WTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRN--LQPASEYTVSLVAIKGNQE 1074
            W+PP      YR+ +            VG   ++Y + +  L P  +Y V ++   GN +
Sbjct: 398  WSPPAGDWEQYRILL-FNDSVVLLNITVGKEETQYVMDDTGLVPGRQYEVEVIVESGNLK 456

Query: 1075 SPKATGVFTTLQPGSSIPPYNTEVTETTIVITW-TP-APRIGFKLGVRPSQGGEAPREVT 1132
            + +     T   P + +        ET++ I W TP A    + + +         + ++
Sbjct: 457  NSERCQGRTV--PLAVLQLRVKHANETSLSIMWQTPVAEWEKYIISLADRDLLLIHKSLS 514

Query: 1133 SDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLT 1192
             D+     + L PG +Y+ T+  +    +  + +  + V   +  T+LH+     T  L 
Sbjct: 515  KDAKEFTFTDLVPGRKYMATVTSISGDLKNSSSVKGRTVP--AQVTDLHVANQGMTSSLF 572

Query: 1193 VSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKD 1252
             +W ++   D+  Y++     N    N   E + ++ S  +F +L  G  Y+V V TV  
Sbjct: 573  TNWTQAQG-DVEFYQVLLIHENVVIKN---ESISSETSRYSFHSLKSGSLYSVVVTTVSG 628

Query: 1253 DKES--VPISDTIIPAVPPPTDLRFTNIGP-DTMRVTWAPPPSIDLTNFLVRYSPVKNEE 1309
               S  V +    +P+    + +   N G  D + V+W   P  D+ N+ V  S   + +
Sbjct: 629  GISSRQVVVEGRTVPS--SVSGVTVNNSGRNDYLSVSWLLAPG-DVDNYEVTLS--HDGK 683

Query: 1310 DVAELSISPSDNAVVLTNLLPGTEYVVSV---SSVYEQHESTPLRGRQKTGLDSPTGIDF 1366
             V  L I+ S      ++L PG  Y V++   S  YE H  +    +++T  D   G+  
Sbjct: 684  VVQSLVIAKSVRECSFSSLTPGRLYTVTITTRSGKYENHSFS----QERTVPDKVQGVSV 739

Query: 1367 SDITANSFT-VHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYV 1425
            S+   + +  V W+        Y +    ++   + +   +P S N      L PG  Y 
Sbjct: 740  SNSARSDYLRVSWVHATGDFDHYEVTIKNKNNFIQTKS--IPKSENECVFVQLVPGRLYS 797

Query: 1426 VSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRIT--YG 1483
            V++   +G+ E+    G   T+ +  +DL +   +   L ++W      V  Y I   + 
Sbjct: 798  VTVTTKSGQYEANEQ-GNGRTIPEPVKDLTLRNRSTEDLHVTWSGANGDVDQYEIQLLFN 856

Query: 1484 ETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEID 1543
            +     P   F +  + +    + L PG  Y I V  ++G     A  +  ++    +  
Sbjct: 857  DMKVFPP---FHLVNTATEYRFTSLTPGRQYKILVLTISGDVQQSAFIEGFTVPSAVKNI 913

Query: 1544 KPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQ 1603
              S    TD    S++V W P    V  Y V+    +      ++T      E T   L+
Sbjct: 914  HISPNGATD----SLTVNWTPGGGDVDSYTVSAFRHSQK--VDSQTIPKHVFEHTFHRLE 967

Query: 1604 PTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYR 1663
               +Y + + + + S ++Q  V            +A       S+ ++W+   G   RY 
Sbjct: 968  AGEQYQIMIASVSGSLKNQINVVGRTVPASVQGVIADNAYSSYSLIVSWQKAAGVAERYD 1027

Query: 1664 VTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIP 1723
            +   + E+GI     +        + + L PG +Y + ++ +   + S+       T   
Sbjct: 1028 ILLLT-ENGILLRNTSEPATTKQHKFEDLTPGKKYKIQILTVSGGLFSKEAQTEGRTVPA 1086

Query: 1724 APTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKE-INLAPDSSSVVVSGL 1782
            A TDL+ T+ +   LS +WT    +L+ Y + +   +  G ++E   + P   S     L
Sbjct: 1087 AVTDLRITENSTRHLSFRWTASEGELSWYNIFLYNPD--GNLQERAQVDPLVQSFSFQNL 1144

Query: 1783 MVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETIT 1842
            +    Y++ +      L++       T   +VS  R +     T  ++  +W   +    
Sbjct: 1145 LQGRMYKMVIVTHSGELSNESFIFGRTVPASVSHLRGSNRN--TTDSLWFNWSPASGDFD 1202

Query: 1843 GFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTA 1902
             +++     NG T  +     D+  +   GL PG  Y +++ T +    S+ V  ++ TA
Sbjct: 1203 FYELILYNPNG-TKKENWKDKDLTEWRFQGLVPGRKYVLWVVT-HSGDLSNKVTAESRTA 1260

Query: 1903 IDAPSNLRFLATTPNSLLVSWQPP 1926
               PS + F      SL ++W+ P
Sbjct: 1261 PSPPSLMSFADIANTSLAITWKGP 1284



 Score =  154 bits (389), Expect = 1e-36
 Identities = 268/1271 (21%), Positives = 471/1271 (37%), Gaps = 99/1271 (7%)

Query: 662  HLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPL 721
            H  SY   GL PG +Y   L  + +    +  R+    T                  +P+
Sbjct: 251  HATSYAFHGLTPGYLY--NLTVMTEAAGLQNYRWKLVRT------------------APM 290

Query: 722  VATSESVT-EITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL 780
              ++  VT + + +S  V W      V  + +   LS +G   +   L    T  +  +L
Sbjct: 291  EVSNLKVTNDGSLTSLKVKWQRPPGNVDSYNI--TLSHKGTIKESRVLAPWITETHFKEL 348

Query: 781  LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDD-TSIVVRWSRPQAPIT 839
            +PGR Y V V  +S  GE S        T PD   +   +      S+VV WS P     
Sbjct: 349  VPGRLYQVTVSCVS--GELSAQKMAVGRTFPDKVANLEANNNGRMRSLVVSWSPPAGDWE 406

Query: 840  GYRI-VYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQET 898
             YRI +++ SV   +  +   ET   +  + L PG QY + +     N +++        
Sbjct: 407  QYRILLFNDSVVLLNITVGKEETQYVMDDTGLVPGRQYEVEVIVESGNLKNSE------- 459

Query: 899  TGTPRSDTVP-SPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPIS 957
                +  TVP +   L+     +  ++IMW  P +    Y + +   +L   H + L   
Sbjct: 460  --RCQGRTVPLAVLQLRVKHANETSLSIMWQTPVAEWEKYIISLADRDLLLIH-KSLSKD 516

Query: 958  RNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNE-TDSTVLVR 1016
               F   T L PG  Y   V ++S   ++      +T      T+L   N+   S++   
Sbjct: 517  AKEFT-FTDLVPGRKYMATVTSISGDLKNSSSVKGRTVPAQV-TDLHVANQGMTSSLFTN 574

Query: 1017 WTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESP 1076
            WT  +  +  Y++ + +      +  ++    S+Y   +L+  S Y+V +  + G   S 
Sbjct: 575  WTQAQGDVEFYQVLL-IHENVVIKNESISSETSRYSFHSLKSGSLYSVVVTTVSGGISSR 633

Query: 1077 KATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPRE--VTSD 1134
            +      T+    S    N       + ++W  AP       V  S  G+  +   +   
Sbjct: 634  QVVVEGRTVPSSVSGVTVNNSGRNDYLSVSWLLAPGDVDNYEVTLSHDGKVVQSLVIAKS 693

Query: 1135 SGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVS 1194
                  S LTPG  Y  TI       E  +    + V       ++   A  D   L VS
Sbjct: 694  VRECSFSSLTPGRLYTVTITTRSGKYENHSFSQERTVPDKVQGVSVSNSARSD--YLRVS 751

Query: 1195 WERSTTPDITGYRITTTPTNGQQGNSLE-EVVHADQSSCTFDNLSPGLEYNVSVYTVKDD 1253
            W  + T D   Y +T    N    N ++ + +   ++ C F  L PG  Y+V+V T    
Sbjct: 752  WVHA-TGDFDHYEVTIKNKN----NFIQTKSIPKSENECVFVQLVPGRLYSVTVTTKSGQ 806

Query: 1254 KESVPISD-TIIPAVPPPTDLRFTNIGPDTMRVTWA-PPPSIDLTNFLVRYSPVKNEEDV 1311
             E+    +   IP   P  DL   N   + + VTW+     +D     + ++ +K     
Sbjct: 807  YEANEQGNGRTIP--EPVKDLTLRNRSTEDLHVTWSGANGDVDQYEIQLLFNDMK---VF 861

Query: 1312 AELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITA 1371
                +  +      T+L PG +Y + V ++    + +        G   P+ +    I+ 
Sbjct: 862  PPFHLVNTATEYRFTSLTPGRQYKILVLTISGDVQQSAF----IEGFTVPSAVKNIHISP 917

Query: 1372 N----SFTVHWIAPRATITGYRI---RHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEY 1424
            N    S TV+W      +  Y +   RH     S +     +P      T   L  G +Y
Sbjct: 918  NGATDSLTVNWTPGGGDVDSYTVSAFRH-----SQKVDSQTIPKHVFEHTFHRLEAGEQY 972

Query: 1425 VVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWD-APAVTVRYYRITYG 1483
             + I +++G  ++ + +  ++  + V   +   A +  SL++SW  A  V  RY  +   
Sbjct: 973  QIMIASVSGSLKNQINVVGRTVPASVQGVIADNAYSSYSLIVSWQKAAGVAERYDILLLT 1032

Query: 1484 ETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEID 1543
            E G    ++  + P +        L PG  Y I +  V+G       SK      RT   
Sbjct: 1033 ENG--ILLRNTSEPATTKQHKFEDLTPGKKYKIQILTVSG----GLFSKEAQTEGRTVPA 1086

Query: 1544 KPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQ 1603
              + +++T+     +S +W  S   ++ Y +     +G    + +     Q+      LQ
Sbjct: 1087 AVTDLRITENSTRHLSFRWTASEGELSWYNIFLYNPDGNLQERAQVDPLVQSFSFQNLLQ 1146

Query: 1604 PTV-EYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRY 1662
              + + V+  ++   S ES    +T   ++   +G        DS+   W    G    Y
Sbjct: 1147 GRMYKMVIVTHSGELSNESFIFGRTVPASVSHLRG--SNRNTTDSLWFNWSPASGDFDFY 1204

Query: 1663 RVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAI 1722
             +   +P     E +   D  E     QGL PG +Y + VV    D+ ++  +  +S   
Sbjct: 1205 ELILYNPNGTKKENWKDKDLTE--WRFQGLVPGRKYVLWVVTHSGDLSNK--VTAESRTA 1260

Query: 1723 PAPTDL-KFTQVTPTSLSAQWT-PPN-VQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVV 1779
            P+P  L  F  +  TSL+  W  PP+      + ++  P++        N    S   +V
Sbjct: 1261 PSPPSLMSFADIANTSLAITWKGPPDWTDYNDFELQWLPRDALTVFNPYN-NRKSEGRIV 1319

Query: 1780 SGLMVATKYEVSVYALKD---TLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRT 1836
             GL     Y+ +V  +        S+P  G V T  +       R  ++  T I  SW  
Sbjct: 1320 YGLRPGRSYQFNVKTVSGDSWKTYSKPIFGSVRTKPDKIQNLHCRPQNS--TAIACSWIP 1377

Query: 1837 KTETITGFQVDAVPANGQ-TPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPV 1895
                  G+ ++    + Q     R ++ +     I  L P   Y + +   +    S  V
Sbjct: 1378 PDSDFDGYSIECRKMDTQEVEFSRKLEKEKSLLNIMMLVPHKRYLVSIKVQSAGMTSEVV 1437

Query: 1896 VIDASTAIDAP 1906
                 T ID P
Sbjct: 1438 EDSTITMIDRP 1448



 Score =  150 bits (379), Expect = 1e-35
 Identities = 272/1321 (20%), Positives = 506/1321 (38%), Gaps = 92/1321 (6%)

Query: 693  TRFDFTTTSTSTPVTSNTV--TGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGF 750
            ++++   T+ S    S +V   G T P SP+     S     A+S ++SW   S  V  +
Sbjct: 177  SKYNIAITAVSGGKRSFSVYTNGSTVP-SPVKDIGISTK---ANSLLISWSHGSGNVERY 232

Query: 751  RVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISED-GEQSLILSTSQTT 809
            R+   L ++G       +   ATS     L PG  Y+ N+  ++E  G Q+      +T 
Sbjct: 233  RLM--LMDKGILVHGGVVDKHATSYAFHGLTPG--YLYNLTVMTEAAGLQNYRWKLVRTA 288

Query: 810  APDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSD 869
              +       +    TS+ V+W RP   +  Y I  S       + +  P    +    +
Sbjct: 289  PMEVSNLKVTNDGSLTSLKVKWQRPPGNVDSYNITLSHKGTIKESRVLAPWITET-HFKE 347

Query: 870  LQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTP 929
            L PG  Y +T+  V     S  +  Q+   G    D V +        +  + V+  W+P
Sbjct: 348  LVPGRLYQVTVSCV-----SGELSAQKMAVGRTFPDKVANLEANNNGRMRSLVVS--WSP 400

Query: 930  PESAVTGYRV-----DVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGR 984
            P      YR+      V+ +N+     +   +  +T     GL PG  Y  +V   S   
Sbjct: 401  PAGDWEQYRILLFNDSVVLLNITVGKEETQYVMDDT-----GLVPGRQYEVEVIVESGNL 455

Query: 985  ESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNV 1044
            ++      +T  L A   L+  +  ++++ + W  P A+   Y +++   R       ++
Sbjct: 456  KNSERCQGRTVPL-AVLQLRVKHANETSLSIMWQTPVAEWEKYIISLA-DRDLLLIHKSL 513

Query: 1045 GPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIV 1104
                 ++   +L P  +Y  ++ +I G+ ++  +    T     + +   N  +T +++ 
Sbjct: 514  SKDAKEFTFTDLVPGRKYMATVTSISGDLKNSSSVKGRTVPAQVTDLHVANQGMT-SSLF 572

Query: 1105 ITWTPAPR-IGFKLGVRPSQGGEAPRE-VTSDSGSIVVSGLTPGVEYVYTIQVLRDGQER 1162
              WT A   + F   +   +      E ++S++       L  G  Y   +  +  G   
Sbjct: 573  TNWTQAQGDVEFYQVLLIHENVVIKNESISSETSRYSFHSLKSGSLYSVVVTTVSGGISS 632

Query: 1163 DAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLE 1222
               +V     P S  + + +  +     L+VSW  +   D+  Y +T +  +G+   SL 
Sbjct: 633  RQVVVEGRTVP-SSVSGVTVNNSGRNDYLSVSWLLAPG-DVDNYEVTLSH-DGKVVQSL- 688

Query: 1223 EVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS-DTIIPAVPPPTDLRFTNIGPD 1281
             V+      C+F +L+PG  Y V++ T     E+   S +  +P       +   +   D
Sbjct: 689  -VIAKSVRECSFSSLTPGRLYTVTITTRSGKYENHSFSQERTVPDKVQGVSVS-NSARSD 746

Query: 1282 TMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAEL-SISPSDNAVVLTNLLPGTEYVVSVSS 1340
             +RV+W      D  ++ V    +KN+ +  +  SI  S+N  V   L+PG  Y V+V++
Sbjct: 747  YLRVSWVHATG-DFDHYEVT---IKNKNNFIQTKSIPKSENECVFVQLVPGRLYSVTVTT 802

Query: 1341 VYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGR 1400
               Q+E+   +G  +T  +    +   + +     V W      +  Y I+         
Sbjct: 803  KSGQYEANE-QGNGRTIPEPVKDLTLRNRSTEDLHVTWSGANGDVDQYEIQLLFNDMKVF 861

Query: 1401 PREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAAT 1460
            P    V ++      T+LTPG +Y + ++ ++G  +    I +  TV    +++ +    
Sbjct: 862  PPFHLV-NTATEYRFTSLTPGRQYKILVLTISGDVQQSAFI-EGFTVPSAVKNIHISPNG 919

Query: 1461 PT-SLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVY 1519
             T SL ++W      V  Y  T      +  V   T+P      T   L+ G  Y I + 
Sbjct: 920  ATDSLTVNWTPGGGDVDSY--TVSAFRHSQKVDSQTIPKHVFEHTFHRLEAGEQYQIMIA 977

Query: 1520 AVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSIS-----VKWLPSSSPVTGYRV 1574
            +V+G     +    I++  RT    P+ +Q   + DN+ S     V W  ++     Y +
Sbjct: 978  SVSG-----SLKNQINVVGRTV---PASVQGV-IADNAYSSYSLIVSWQKAAGVAERYDI 1028

Query: 1575 TTTPKNGPGPTKTKTAGPDQTEM-TIEGLQPTVEYVVSVYAQNP---SGESQP---LVQT 1627
                +NG       T+ P  T+    E L P  +Y + +   +    S E+Q     V  
Sbjct: 1029 LLLTENGI--LLRNTSEPATTKQHKFEDLTPGKKYKIQILTVSGGLFSKEAQTEGRTVPA 1086

Query: 1628 AVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTA 1687
            AVT+      L  T+     +   W + +G++S Y +   +P+  + E     D    + 
Sbjct: 1087 AVTD------LRITENSTRHLSFRWTASEGELSWYNIFLYNPDGNLQERAQV-DPLVQSF 1139

Query: 1688 ELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNV 1747
              Q L  G  Y + +V    ++ ++  I  ++            + T  SL   W+P + 
Sbjct: 1140 SFQNLLQGRMYKMVIVTHSGELSNESFIFGRTVPASVSHLRGSNRNTTDSLWFNWSPASG 1199

Query: 1748 QLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGV 1807
                Y + +      G  KE     D +     GL+   KY + V      L+++     
Sbjct: 1200 DFDFYELILY--NPNGTKKENWKDKDLTEWRFQGLVPGRKYVLWVVTHSGDLSNKVTAES 1257

Query: 1808 VTTLENVSPPRRARVTDATETTITISWRTKTE--TITGFQVDAVPANGQTPIQRTIKPDV 1865
             T     SPP      D   T++ I+W+   +      F++  +P +  T          
Sbjct: 1258 RTA---PSPPSLMSFADIANTSLAITWKGPPDWTDYNDFELQWLPRDALTVFNPYNNRKS 1314

Query: 1866 RSYTITGLQPGTDYKIYLYTLNDNA---RSSPVVIDASTAIDAPSNLRFLATTPNSLLVS 1922
                + GL+PG  Y+  + T++ ++    S P+     T  D   NL        ++  S
Sbjct: 1315 EGRIVYGLRPGRSYQFNVKTVSGDSWKTYSKPIFGSVRTKPDKIQNLHCRPQNSTAIACS 1374

Query: 1923 WQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKS 1982
            W PP +   GY I+  K  +   E   +     +   I  L P   Y + +        S
Sbjct: 1375 WIPPDSDFDGYSIECRKMDTQEVEFSRKLEKEKSLLNIMMLVPHKRYLVSIKVQSAGMTS 1434

Query: 1983 E 1983
            E
Sbjct: 1435 E 1435



 Score =  141 bits (356), Expect = 7e-33
 Identities = 241/1202 (20%), Positives = 454/1202 (37%), Gaps = 115/1202 (9%)

Query: 826  SIVVRWSRPQAPITGYRIVYSPSVEGSST--ELNLPETANSVTLSDLQPGVQYNITIYAV 883
            S+ ++W    +P   + ++YS    G++      +  T     L DLQ G  YN  I ++
Sbjct: 40   SVSIQWRILGSPCN-FSLIYSSDTLGAALCPTFRIDNTTYGCNLQDLQAGTIYNFRIISL 98

Query: 884  EENQESTPVVIQQETTGTPRSDTVPSPR-DLQFVEVTDVKVTIMWTPPESAVTGYRVDVI 942
            +E           E T   ++D +P  R  +   + T   + + WTP    VT Y V + 
Sbjct: 99   DE-----------ERTVVLQTDPLPPARFGVSKEKTTSTSLHVWWTPSSGKVTSYEVQLF 147

Query: 943  PVNLPGEHGQRLPISRNTFAEVT--GLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAP 1000
              N     G ++  S  ++ E T   L+ G  Y   + AVS G+ S  +    +T + +P
Sbjct: 148  DENNQKIQGVQIQES-TSWNEYTFFNLTAGSKYNIAITAVSGGKRSFSVYTNGST-VPSP 205

Query: 1001 TNLQFVNETDSTVLVRWTPPRAQITGYRLTV---GLTRRGQPRQYNVGPSVSKYPLRNLQ 1057
                 ++   +++L+ W+     +  YRL +   G+   G      V    + Y    L 
Sbjct: 206  VKDIGISTKANSLLISWSHGSGNVERYRLMLMDKGILVHGGV----VDKHATSYAFHGLT 261

Query: 1058 PASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKL 1117
            P   Y ++++      ++ +   V T     S++   N + + T++ + W   P      
Sbjct: 262  PGYLYNLTVMTEAAGLQNYRWKLVRTAPMEVSNLKVTN-DGSLTSLKVKWQRPPGNVDSY 320

Query: 1118 GVRPSQGG--EAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLS 1175
             +  S  G  +  R +           L PG  Y  T+  +          V +      
Sbjct: 321  NITLSHKGTIKESRVLAPWITETHFKELVPGRLYQVTVSCVSGELSAQKMAVGRTF---- 376

Query: 1176 PPTNLHLEANPDTGV--LTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCT 1233
            P    +LEAN +  +  L VSW      D   YRI            L   V  +++   
Sbjct: 377  PDKVANLEANNNGRMRSLVVSWS-PPAGDWEQYRILLF---NDSVVLLNITVGKEETQYV 432

Query: 1234 FDN--LSPGLEYNVSVYTVKDD-KESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPP 1290
             D+  L PG +Y V V     + K S       +P       LR  +    ++ + W  P
Sbjct: 433  MDDTGLVPGRQYEVEVIVESGNLKNSERCQGRTVPLA--VLQLRVKHANETSLSIMWQTP 490

Query: 1291 PSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVY-EQHESTP 1349
             + +   +++  S    +  +   S+S        T+L+PG +Y+ +V+S+  +   S+ 
Sbjct: 491  VA-EWEKYII--SLADRDLLLIHKSLSKDAKEFTFTDLVPGRKYMATVTSISGDLKNSSS 547

Query: 1350 LRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHS 1409
            ++GR      +   +    +T++ FT +W   +  +  Y++    E+     + + +   
Sbjct: 548  VKGRTVPAQVTDLHVANQGMTSSLFT-NWTQAQGDVEFYQVLLIHENVV--IKNESISSE 604

Query: 1410 RNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTS----LL 1465
             +  +  +L  G+ Y V +  ++G   S  ++ +  T   VP  +  V    +     L 
Sbjct: 605  TSRYSFHSLKSGSLYSVVVTTVSGGISSRQVVVEGRT---VPSSVSGVTVNNSGRNDYLS 661

Query: 1466 ISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRG 1525
            +SW      V  Y +T    G    VQ   +  S    + S L PG  YT+T+   +G+ 
Sbjct: 662  VSWLLAPGDVDNYEVTLSHDG--KVVQSLVIAKSVRECSFSSLTPGRLYTVTITTRSGKY 719

Query: 1526 DSPASSKPISINYRTEIDKPSQMQVTD-VQDNSISVKWLPSSSPVTGYRVTTTPKNGPGP 1584
            ++ + S+      RT  DK   + V++  + + + V W+ ++     Y VT   KN    
Sbjct: 720  ENHSFSQE-----RTVPDKVQGVSVSNSARSDYLRVSWVHATGDFDHYEVTIKNKN--NF 772

Query: 1585 TKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRP-KGLAFTDV 1643
             +TK+    + E     L P   Y V+V  +  SG+ +   Q     I  P K L   + 
Sbjct: 773  IQTKSIPKSENECVFVQLVPGRLYSVTVTTK--SGQYEANEQGNGRTIPEPVKDLTLRNR 830

Query: 1644 DVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTA---ELQGLRPGSEYTV 1700
              + + + W    G V +Y +     +    ++FP P    +TA       L PG +Y +
Sbjct: 831  STEDLHVTWSGANGDVDQYEIQLLFND---MKVFP-PFHLVNTATEYRFTSLTPGRQYKI 886

Query: 1701 SVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPT----SLSAQWTPPNVQLTGYRV-- 1754
             V+ +  D++    I         P+ +K   ++P     SL+  WTP    +  Y V  
Sbjct: 887  LVLTISGDVQQSAFI----EGFTVPSAVKNIHISPNGATDSLTVNWTPGGGDVDSYTVSA 942

Query: 1755 ---------RVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQ 1805
                     +  PK           A +   ++++ +  + K +++V            Q
Sbjct: 943  FRHSQKVDSQTIPKHVFEHTFHRLEAGEQYQIMIASVSGSLKNQINVVG---RTVPASVQ 999

Query: 1806 GVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKP-D 1864
            GV+                 +  ++ +SW+        + +  +  NG   ++ T +P  
Sbjct: 1000 GVIAD------------NAYSSYSLIVSWQKAAGVAERYDILLLTENG-ILLRNTSEPAT 1046

Query: 1865 VRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQ 1924
             + +    L PG  YKI + T++    S     +  T   A ++LR    +   L   W 
Sbjct: 1047 TKQHKFEDLTPGKKYKIQILTVSGGLFSKEAQTEGRTVPAAVTDLRITENSTRHLSFRWT 1106

Query: 1925 PPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEP 1984
                 ++ Y I    P    +E   +  P V   +   L  G  Y + ++       +E 
Sbjct: 1107 ASEGELSWYNIFLYNPDGNLQERA-QVDPLVQSFSFQNLLQGRMYKMVIVTHSGELSNES 1165

Query: 1985 LI 1986
             I
Sbjct: 1166 FI 1167



 Score =  102 bits (255), Expect = 3e-21
 Identities = 218/1016 (21%), Positives = 374/1016 (36%), Gaps = 81/1016 (7%)

Query: 698  TTTSTSTPV-TSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYEL 756
            T TS S  +  S++V G T P    V       +   SS   +W  A   V  ++V   L
Sbjct: 534  TVTSISGDLKNSSSVKGRTVPAQ--VTDLHVANQGMTSSLFTNWTQAQGDVEFYQVL--L 589

Query: 757  SEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPD 816
              E    +   + S  +  +   L  G  Y V V  +S  G  S  +     T P +   
Sbjct: 590  IHENVVIKNESISSETSRYSFHSLKSGSLYSVVVTTVS-GGISSRQVVVEGRTVPSSVSG 648

Query: 817  PTVDQVDDTSIV-VRWSRPQAPITGYRIVYSPSVEGSSTE-LNLPETANSVTLSDLQPGV 874
             TV+       + V W      +  Y +  S   +G   + L + ++    + S L PG 
Sbjct: 649  VTVNNSGRNDYLSVSWLLAPGDVDNYEVTLSH--DGKVVQSLVIAKSVRECSFSSLTPGR 706

Query: 875  QYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVK----VTIMWTPP 930
             Y +TI       E+      QE T          P  +Q V V++      + + W   
Sbjct: 707  LYTVTITTRSGKYENHS--FSQERT---------VPDKVQGVSVSNSARSDYLRVSWVHA 755

Query: 931  ESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLT 990
                  Y V +   N      + +P S N    V  L PG  Y   V   S   E+    
Sbjct: 756  TGDFDHYEVTIKNKN-NFIQTKSIPKSENECVFVQ-LVPGRLYSVTVTTKSGQYEANEQG 813

Query: 991  AQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSK 1050
              +T   +   +L   N +   + V W+     +  Y + +          +++  + ++
Sbjct: 814  NGRTIP-EPVKDLTLRNRSTEDLHVTWSGANGDVDQYEIQLLFNDMKVFPPFHLVNTATE 872

Query: 1051 YPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPA 1110
            Y   +L P  +Y + ++ I G+ +       FT      +I       T++ + + WTP 
Sbjct: 873  YRFTSLTPGRQYKILVLTISGDVQQSAFIEGFTVPSAVKNIHISPNGATDS-LTVNWTPG 931

Query: 1111 PRIGFKLGV---RPSQGGEA---PREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDA 1164
                    V   R SQ  ++   P+ V   +       L  G +Y   I  +    +   
Sbjct: 932  GGDVDSYTVSAFRHSQKVDSQTIPKHVFEHT----FHRLEAGEQYQIMIASVSGSLKNQI 987

Query: 1165 PIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEV 1224
             +V + V P S    +   A     ++ VSW+++       Y I     NG    +  E 
Sbjct: 988  NVVGRTV-PASVQGVIADNAYSSYSLI-VSWQKAAGV-AERYDILLLTENGILLRNTSEP 1044

Query: 1225 VHADQSSCTFDNLSPGLEYNVSVYTVKD---DKESVPISDTIIPAVPPPTDLRFTNIGPD 1281
                Q    F++L+PG +Y + + TV      KE+     T+  AV   TDLR T     
Sbjct: 1045 ATTKQHK--FEDLTPGKKYKIQILTVSGGLFSKEAQTEGRTVPAAV---TDLRITENSTR 1099

Query: 1282 TMRVTW-APPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEY-VVSVS 1339
             +   W A    +   N  + Y+P  N ++ A+  + P   +    NLL G  Y +V V+
Sbjct: 1100 HLSFRWTASEGELSWYNIFL-YNPDGNLQERAQ--VDPLVQSFSFQNLLQGRMYKMVIVT 1156

Query: 1340 SVYEQHESTPLRGRQ-KTGLDSPTGIDFSDITANSFTVHWIAPRATITGYR-IRHHPEHF 1397
               E    + + GR     +    G + +  T +S   +W         Y  I ++P   
Sbjct: 1157 HSGELSNESFIFGRTVPASVSHLRGSNRN--TTDSLWFNWSPASGDFDFYELILYNP--- 1211

Query: 1398 SGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVV 1457
            +G  +E+             L PG +YV+ +V  +G + S  +  +  T    P  +   
Sbjct: 1212 NGTKKENWKDKDLTEWRFQGLVPGRKYVLWVVTHSG-DLSNKVTAESRTAPSPPSLMSFA 1270

Query: 1458 AATPTSLLISWDAPAVTVRY--YRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYT 1515
                TSL I+W  P     Y  + + +      +    +    S+    + GL+PG  Y 
Sbjct: 1271 DIANTSLAITWKGPPDWTDYNDFELQWLPRDALTVFNPYNNRKSEGRI-VYGLRPGRSYQ 1329

Query: 1516 ITVYAVTGRGDS-PASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRV 1574
              V  V+G  DS    SKPI  + RT+ DK   +        +I+  W+P  S   GY +
Sbjct: 1330 FNVKTVSG--DSWKTYSKPIFGSVRTKPDKIQNLHCRPQNSTAIACSWIPPDSDFDGYSI 1387

Query: 1575 TTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDR 1634
                 +      ++    +++ + I  L P   Y+VS+  Q+    S+ +  + +T IDR
Sbjct: 1388 ECRKMDTQEVEFSRKLEKEKSLLNIMMLVPHKRYLVSIKVQSAGMTSEVVEDSTITMIDR 1447

Query: 1635 P-----------KGLAFTDVDVD-SIKIAWESPQGQVSRYRVTYSSPEDGIHELFP 1678
            P           K +  +   ++ ++  +W S      +Y        DG  EL P
Sbjct: 1448 PPPPPPHIRVNEKDVLISKSSINFTVNCSWFSDTNGAVKYFTVVVREADGSDELKP 1503



 Score = 35.8 bits (81), Expect = 0.50
 Identities = 32/136 (23%), Positives = 57/136 (41%), Gaps = 6/136 (4%)

Query: 1860 TIKPDVRSY--TITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPN 1917
            T + D  +Y   +  LQ GT Y   + +L++      VV+       A   +    TT  
Sbjct: 70   TFRIDNTTYGCNLQDLQAGTIYNFRIISLDEERT---VVLQTDPLPPARFGVSKEKTTST 126

Query: 1918 SLLVSWQPPRARITGYIIK-YEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIAL 1976
            SL V W P   ++T Y ++ +++     + V  +      E T   L  G++Y I + A+
Sbjct: 127  SLHVWWTPSSGKVTSYEVQLFDENNQKIQGVQIQESTSWNEYTFFNLTAGSKYNIAITAV 186

Query: 1977 KNNQKSEPLIGRKKTV 1992
               ++S  +     TV
Sbjct: 187  SGGKRSFSVYTNGSTV 202



 Score = 35.4 bits (80), Expect = 0.66
 Identities = 37/194 (19%), Positives = 76/194 (39%), Gaps = 25/194 (12%)

Query: 628  IQWNAPQP-SHISKYILRWRPKNSV---GRWKEATIPGHLNSYTIKGLKPGVVYEGQLIS 683
            I W  P   +  + + L+W P++++     +      G +    + GL+PG  Y+  + +
Sbjct: 1279 ITWKGPPDWTDYNDFELQWLPRDALTVFNPYNNRKSEGRI----VYGLRPGRSYQFNVKT 1334

Query: 684  IQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSA 743
            +     +  ++  F +  T      N           L    ++ T I  S     W+  
Sbjct: 1335 VSGDSWKTYSKPIFGSVRTKPDKIQN-----------LHCRPQNSTAIACS-----WIPP 1378

Query: 744  SDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLIL 803
                 G+ +E    +  +      L    + +NI  L+P ++Y+V++ ++   G  S ++
Sbjct: 1379 DSDFDGYSIECRKMDTQEVEFSRKLEKEKSLLNIMMLVPHKRYLVSI-KVQSAGMTSEVV 1437

Query: 804  STSQTTAPDAPPDP 817
              S  T  D PP P
Sbjct: 1438 EDSTITMIDRPPPP 1451


>gi|112734845 collagen, type XX, alpha 1 [Homo sapiens]
          Length = 1284

 Score =  155 bits (392), Expect = 4e-37
 Identities = 147/533 (27%), Positives = 232/533 (43%), Gaps = 31/533 (5%)

Query: 1115 FKLGVRPSQGGEA------PREVTSDSG-SIVVSGLTPGVEYVYTIQVLRDGQERDAPIV 1167
            F +GV+ +   E       PR++T  S    +  G   G+      Q L+ G  R  P  
Sbjct: 311  FAVGVKNADEAELRLLASPPRDITVHSVLDFLQLGALAGLLSRLICQRLQGGSPRQGPAA 370

Query: 1168 NKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHA 1227
               +  L  PT+L L     + +  +SW  +    +  Y I    + G  G   E VV  
Sbjct: 371  APALDTLPAPTSLVLSQVTSSSI-RLSWTPAPRHPLK-YLIVWRASRG--GTPREVVVEG 426

Query: 1228 DQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPA-VPPPTDLRFTNIGPDTMRVT 1286
              +S    NL+   EY VSV+ + +      +   +  A +PPP  L    + P T+ +T
Sbjct: 427  PAASTELHNLASRTEYLVSVFPIYEGGVGEGLRGLVTTAPLPPPRALTLAAVTPRTVHLT 486

Query: 1287 WAPPPSIDLTNFLVRYSPV--KNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVY-- 1342
            W P  S   T++LVR SP   K EE+  E+ +   +  V+L  L PG +Y VSV S+   
Sbjct: 487  WQP--SAGATHYLVRCSPASPKGEEEEREVQVGRPE--VLLDGLEPGRDYEVSVQSLRGP 542

Query: 1343 EQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPR 1402
            E  E+  +R R  T L  P  + FSD++ ++  V W      +   R+ +      G   
Sbjct: 543  EGSEARGIRARTPT-LAPPRHLGFSDVSHDAARVFWEGAPRPVRLVRVTYVSSE-GGHSG 600

Query: 1403 EDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTV-SDVPRDLEVVAATP 1461
            +   P +  S TL  L+  T Y V +  L     S  L G+ +T  +  P  L +     
Sbjct: 601  QTEAPGNATSATLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVTTKKAPSPSQLSMTELPG 660

Query: 1462 TSLLISWDAPAVT-VRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYA 1520
             ++ ++W A A + V  Y+IT+   G      E +VPG+  TA + GL    +Y +T+ A
Sbjct: 661  DAVQLAWVAAAPSGVLVYQITWTPLG-EGKAHEISVPGNLGTAVLPGLGRHTEYDVTILA 719

Query: 1521 VTGRGDSPASSKPISINYRTEI---DKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTT 1577
                G   A S P+S+ Y         PS + +     +S+ V W P    V  Y +T  
Sbjct: 720  YYRDG---ARSDPVSLRYTPSTVSRSPPSNLALASETPDSLQVSWTPPLGRVLHYWLTYA 776

Query: 1578 PKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVT 1630
            P +G GP K+ +    ++ +T+  LQ   +Y V V A   +G S+ +  T  T
Sbjct: 777  PASGLGPEKSVSVPGARSHVTLPDLQAATKYRVLVSAIYAAGRSEAVSATGQT 829



 Score =  146 bits (369), Expect = 2e-34
 Identities = 133/449 (29%), Positives = 203/449 (45%), Gaps = 22/449 (4%)

Query: 1358 LDSPTGIDFSDITANSFTVHWI-APRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLT 1416
            L +PT +  S +T++S  + W  APR  +  Y I        G PRE  V     S  L 
Sbjct: 377  LPAPTSLVLSQVTSSSIRLSWTPAPRHPLK-YLIVWRASR-GGTPREVVVEGPAASTELH 434

Query: 1417 NLTPGTEYVVSIVALNGREESPLLIGQQSTVS-DVPRDLEVVAATPTSLLISWDAPAVTV 1475
            NL   TEY+VS+  +        L G  +T     PR L + A TP ++ ++W  P+   
Sbjct: 435  NLASRTEYLVSVFPIYEGGVGEGLRGLVTTAPLPPPRALTLAAVTPRTVHLTWQ-PSAGA 493

Query: 1476 RYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPIS 1535
             +Y +           +E  V   +    + GL+PG DY ++V ++ G    P  S+   
Sbjct: 494  THYLVRCSPASPKGEEEEREVQVGRPEVLLDGLEPGRDYEVSVQSLRG----PEGSEARG 549

Query: 1536 INYRTE-IDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQ 1594
            I  RT  +  P  +  +DV  ++  V W  +  PV   RVT     G    +T+  G + 
Sbjct: 550  IRARTPTLAPPRHLGFSDVSHDAARVFWEGAPRPVRLVRVTYVSSEGGHSGQTEAPG-NA 608

Query: 1595 TEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTN-IDRPKGLAFTDVDVDSIKIAW- 1652
            T  T+  L  +  Y V V    P G S  L     T     P  L+ T++  D++++AW 
Sbjct: 609  TSATLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVTTKKAPSPSQLSMTELPGDAVQLAWV 668

Query: 1653 -ESPQGQVSRYRVTYSSPEDG-IHELFPAPDGEEDTAELQGLRPGSEYTVSVVALH-DDM 1709
              +P G V  Y++T++   +G  HE+  +  G   TA L GL   +EY V+++A + D  
Sbjct: 669  AAAPSG-VLVYQITWTPLGEGKAHEI--SVPGNLGTAVLPGLGRHTEYDVTILAYYRDGA 725

Query: 1710 ESQP--LIGTQSTAIPAP-TDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMK 1766
             S P  L  T ST   +P ++L     TP SL   WTPP  ++  Y +   P    GP K
Sbjct: 726  RSDPVSLRYTPSTVSRSPPSNLALASETPDSLQVSWTPPLGRVLHYWLTYAPASGLGPEK 785

Query: 1767 EINLAPDSSSVVVSGLMVATKYEVSVYAL 1795
             +++    S V +  L  ATKY V V A+
Sbjct: 786  SVSVPGARSHVTLPDLQAATKYRVLVSAI 814



 Score =  145 bits (367), Expect = 3e-34
 Identities = 139/474 (29%), Positives = 219/474 (46%), Gaps = 29/474 (6%)

Query: 1073 QESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGV--RPSQGGEAPRE 1130
            ++ P A     TL   +S+    ++VT ++I ++WTPAPR   K  +  R S+GG  PRE
Sbjct: 365  RQGPAAAPALDTLPAPTSL--VLSQVTSSSIRLSWTPAPRHPLKYLIVWRASRGG-TPRE 421

Query: 1131 VTSD--SGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEA-NPD 1187
            V  +  + S  +  L    EY+ ++  + +G   +         PL PP  L L A  P 
Sbjct: 422  VVVEGPAASTELHNLASRTEYLVSVFPIYEGGVGEGLRGLVTTAPLPPPRALTLAAVTPR 481

Query: 1188 TGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSV 1247
            T  LT  W+ S     T Y +  +P +  +G   E  V   +     D L PG +Y VSV
Sbjct: 482  TVHLT--WQPSA--GATHYLVRCSPAS-PKGEEEEREVQVGRPEVLLDGLEPGRDYEVSV 536

Query: 1248 YTVKDDKESVPISDTI-IPAVPPPTDLRFTNIGPDTMRVTW--APPPSIDLTNFLVRYSP 1304
             +++  + S         P + PP  L F+++  D  RV W  AP P       LVR + 
Sbjct: 537  QSLRGPEGSEARGIRARTPTLAPPRHLGFSDVSHDAARVFWEGAPRPVR-----LVRVTY 591

Query: 1305 VKNEEDVAELSISPSD-NAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTG-LDSPT 1362
            V +E   +  + +P +  +  L  L   T Y V V+ +Y    S+ L GR  T    SP+
Sbjct: 592  VSSEGGHSGQTEAPGNATSATLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVTTKKAPSPS 651

Query: 1363 GIDFSDITANSFTVHWIAPRAT-ITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPG 1421
             +  +++  ++  + W+A   + +  Y+I   P    G+  E  VP +  +  L  L   
Sbjct: 652  QLSMTELPGDAVQLAWVAAAPSGVLVYQITWTPLG-EGKAHEISVPGNLGTAVLPGLGRH 710

Query: 1422 TEYVVSIVAL--NGREESPLLIGQQ-STVS-DVPRDLEVVAATPTSLLISWDAPAVTVRY 1477
            TEY V+I+A   +G    P+ +    STVS   P +L + + TP SL +SW  P   V +
Sbjct: 711  TEYDVTILAYYRDGARSDPVSLRYTPSTVSRSPPSNLALASETPDSLQVSWTPPLGRVLH 770

Query: 1478 YRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASS 1531
            Y +TY    G  P +  +VPG++S  T+  L+    Y + V A+   G S A S
Sbjct: 771  YWLTYAPASGLGPEKSVSVPGARSHVTLPDLQAATKYRVLVSAIYAAGRSEAVS 824



 Score =  127 bits (320), Expect = 1e-28
 Identities = 118/470 (25%), Positives = 195/470 (41%), Gaps = 23/470 (4%)

Query: 988  PLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPS 1047
            P  A     L APT+L     T S++ + WTP       Y +    +R G PR+  V   
Sbjct: 368  PAAAPALDTLPAPTSLVLSQVTSSSIRLSWTPAPRHPLKYLIVWRASRGGTPREVVVEGP 427

Query: 1048 VSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYN----TEVTETTI 1103
             +   L NL   +EY VS+  I          G+ TT    + +PP        VT  T+
Sbjct: 428  AASTELHNLASRTEYLVSVFPIYEGGVGEGLRGLVTT----APLPPPRALTLAAVTPRTV 483

Query: 1104 VITWTP---APRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQ 1160
             +TW P   A     +      +G E  REV      +++ GL PG +Y  ++Q LR  +
Sbjct: 484  HLTWQPSAGATHYLVRCSPASPKGEEEEREVQVGRPEVLLDGLEPGRDYEVSVQSLRGPE 543

Query: 1161 ERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNS 1220
              +A  +      L+PP +L   ++       V WE +  P +   R+T   + G  G+S
Sbjct: 544  GSEARGIRARTPTLAPPRHLGF-SDVSHDAARVFWEGAPRP-VRLVRVTYVSSEG--GHS 599

Query: 1221 LEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTI-IPAVPPPTDLRFTNIG 1279
             +     + +S T   LS    Y V V  +     S  ++  +     P P+ L  T + 
Sbjct: 600  GQTEAPGNATSATLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVTTKKAPSPSQLSMTELP 659

Query: 1280 PDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVS 1339
             D +++ W       +  + + ++P+  E    E+S+  +    VL  L   TEY V++ 
Sbjct: 660  GDAVQLAWVAAAPSGVLVYQITWTPL-GEGKAHEISVPGNLGTAVLPGLGRHTEYDVTIL 718

Query: 1340 SVYE---QHESTPLRGRQKT-GLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPE 1395
            + Y    + +   LR    T     P+ +  +  T +S  V W  P   +  Y + + P 
Sbjct: 719  AYYRDGARSDPVSLRYTPSTVSRSPPSNLALASETPDSLQVSWTPPLGRVLHYWLTYAPA 778

Query: 1396 HFSGRPREDRVPHSRNSITLTNLTPGTEY--VVSIVALNGREESPLLIGQ 1443
               G  +   VP +R+ +TL +L   T+Y  +VS +   GR E+    GQ
Sbjct: 779  SGLGPEKSVSVPGARSHVTLPDLQAATKYRVLVSAIYAAGRSEAVSATGQ 828



 Score =  115 bits (287), Expect = 7e-25
 Identities = 125/503 (24%), Positives = 208/503 (41%), Gaps = 40/503 (7%)

Query: 1524 RGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPG 1583
            +G SP    P +      +  P+ + ++ V  +SI + W P+      Y +      G  
Sbjct: 360  QGGSPRQG-PAAAPALDTLPAPTSLVLSQVTSSSIRLSWTPAPRHPLKYLIVWRASRGGT 418

Query: 1584 PTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTN-IDRPKGLAFTD 1642
            P +    GP      +  L    EY+VSV+     G  + L     T  +  P+ L    
Sbjct: 419  PREVVVEGP-AASTELHNLASRTEYLVSVFPIYEGGVGEGLRGLVTTAPLPPPRALTLAA 477

Query: 1643 VDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQ---------GLR 1693
            V   ++ + W+ P    + Y V  S           +P GEE+  E+Q         GL 
Sbjct: 478  VTPRTVHLTWQ-PSAGATHYLVRCSPA---------SPKGEEEEREVQVGRPEVLLDGLE 527

Query: 1694 PGSEYTVSVVALHDDMESQPL-IGTQSTAIPAPTDLKFTQVTPTSLSAQW--TPPNVQLT 1750
            PG +Y VSV +L     S+   I  ++  +  P  L F+ V+  +    W   P  V+L 
Sbjct: 528  PGRDYEVSVQSLRGPEGSEARGIRARTPTLAPPRHLGFSDVSHDAARVFWEGAPRPVRL- 586

Query: 1751 GYRVRVTPKEKTGPMKEINLAP-DSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVT 1809
               VRVT     G       AP +++S  +  L  +T Y V V  L     S    G VT
Sbjct: 587  ---VRVTYVSSEGGHSGQTEAPGNATSATLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVT 643

Query: 1810 TLENVSPPRRARVTDATETTITISWRTKTET-ITGFQVDAVPANGQTPIQRTIKPDVRSY 1868
            T +  SP + + +T+     + ++W     + +  +Q+   P       + ++  ++ + 
Sbjct: 644  TKKAPSPSQLS-MTELPGDAVQLAWVAAAPSGVLVYQITWTPLGEGKAHEISVPGNLGTA 702

Query: 1869 TITGLQPGTDYKIYLYTL-NDNARSSPVVI---DASTAIDAPSNLRFLATTPNSLLVSWQ 1924
             + GL   T+Y + +     D ARS PV +    ++ +   PSNL   + TP+SL VSW 
Sbjct: 703  VLPGLGRHTEYDVTILAYYRDGARSDPVSLRYTPSTVSRSPPSNLALASETPDSLQVSWT 762

Query: 1925 PPRARITGYIIKY-EKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSE 1983
            PP  R+  Y + Y    G  P + V  P    +  T+  L+  T+Y + V A+    +SE
Sbjct: 763  PPLGRVLHYWLTYAPASGLGPEKSVSVP-GARSHVTLPDLQAATKYRVLVSAIYAAGRSE 821

Query: 1984 PL--IGRKKTVQKTPFVTHPGYD 2004
             +   G+       P  + PG+D
Sbjct: 822  AVSATGQTACPALRPDGSLPGFD 844



 Score =  104 bits (259), Expect = 1e-21
 Identities = 112/475 (23%), Positives = 200/475 (42%), Gaps = 23/475 (4%)

Query: 895  QQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRL 954
            +Q     P  DT+P+P  L   +VT   + + WTP       Y + V   +  G   + +
Sbjct: 365  RQGPAAAPALDTLPAPTSLVLSQVTSSSIRLSWTPAPRHPLKYLI-VWRASRGGTPREVV 423

Query: 955  PISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTT-KLDAPTNLQFVNETDSTV 1013
                    E+  L+    Y   VF +  G   + L    TT  L  P  L     T  TV
Sbjct: 424  VEGPAASTELHNLASRTEYLVSVFPIYEGGVGEGLRGLVTTAPLPPPRALTLAAVTPRTV 483

Query: 1014 LVRWTPPRAQITGYRLTVG-LTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGN 1072
             + W  P A  T Y +     + +G+  +  V     +  L  L+P  +Y VS+ +++G 
Sbjct: 484  HLTW-QPSAGATHYLVRCSPASPKGEEEEREVQVGRPEVLLDGLEPGRDYEVSVQSLRG- 541

Query: 1073 QESPKATGVFTTLQPGSSIPPYN---TEVTETTIVITWTPAPRIGFKLGVR--PSQGGEA 1127
             E  +A G+    +  +  PP +   ++V+     + W  APR    + V    S+GG +
Sbjct: 542  PEGSEARGI--RARTPTLAPPRHLGFSDVSHDAARVFWEGAPRPVRLVRVTYVSSEGGHS 599

Query: 1128 PR-EVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSP-PTNLHLEAN 1185
             + E   ++ S  +  L+    Y   +  L  G    + +  +V T  +P P+ L +   
Sbjct: 600  GQTEAPGNATSATLGPLSSSTTYTVRVTCLYPG-GGSSTLTGRVTTKKAPSPSQLSMTEL 658

Query: 1186 PDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNV 1245
            P   V  ++W  +    +  Y+IT TP    +G + E  V  +  +     L    EY+V
Sbjct: 659  PGDAV-QLAWVAAAPSGVLVYQITWTPLG--EGKAHEISVPGNLGTAVLPGLGRHTEYDV 715

Query: 1246 SVYT-VKDDKESVPISDTIIPAV---PPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVR 1301
            ++    +D   S P+S    P+     PP++L   +  PD+++V+W PP    + ++ + 
Sbjct: 716  TILAYYRDGARSDPVSLRYTPSTVSRSPPSNLALASETPDSLQVSWTPPLG-RVLHYWLT 774

Query: 1302 YSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKT 1356
            Y+P         +S+  + + V L +L   T+Y V VS++Y    S  +    +T
Sbjct: 775  YAPASGLGPEKSVSVPGARSHVTLPDLQAATKYRVLVSAIYAAGRSEAVSATGQT 829



 Score =  102 bits (255), Expect = 3e-21
 Identities = 130/522 (24%), Positives = 196/522 (37%), Gaps = 52/522 (9%)

Query: 599  CQPLQTYPSSSGPVEVFITETPSQP----------NSHPIQWNAPQPSHISKYILRWRPK 648
            CQ LQ      GP      +T   P          +S  + W  P P H  KY++ WR  
Sbjct: 356  CQRLQGGSPRQGPAAAPALDTLPAPTSLVLSQVTSSSIRLSWT-PAPRHPLKYLIVWRAS 414

Query: 649  NSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTS 708
               G  +E  + G   S  +  L     Y   +  I + G  E  R    TT+   P   
Sbjct: 415  RG-GTPREVVVEGPAASTELHNLASRTEYLVSVFPIYEGGVGEGLR-GLVTTAPLPP--- 469

Query: 709  NTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDL 768
                       P   T  +VT  T     ++W   S   + + V    +    E +  ++
Sbjct: 470  -----------PRALTLAAVTPRTVH---LTW-QPSAGATHYLVRCSPASPKGEEEEREV 514

Query: 769  PSTATSVNIPDLLPGRKYIVNVYQI--SEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTS 826
                  V +  L PGR Y V+V  +   E  E   I + + T AP  P       V   +
Sbjct: 515  QVGRPEVLLDGLEPGRDYEVSVQSLRGPEGSEARGIRARTPTLAP--PRHLGFSDVSHDA 572

Query: 827  IVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEEN 886
              V W     P+   R+ Y  S  G S +   P  A S TL  L     Y + +  +   
Sbjct: 573  ARVFWEGAPRPVRLVRVTYVSSEGGHSGQTEAPGNATSATLGPLSSSTTYTVRVTCLYPG 632

Query: 887  QESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMW-TPPESAVTGYRVDVIPVN 945
              S+ +      TG   +   PSP  L   E+    V + W     S V  Y++   P+ 
Sbjct: 633  GGSSTL------TGRVTTKKAPSPSQLSMTELPGDAVQLAWVAAAPSGVLVYQITWTPLG 686

Query: 946  LPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFA-VSHGRESKPLTAQ---QTTKLDAPT 1001
                H   +P +  T A + GL     Y   + A    G  S P++ +    T     P+
Sbjct: 687  EGKAHEISVPGNLGT-AVLPGLGRHTEYDVTILAYYRDGARSDPVSLRYTPSTVSRSPPS 745

Query: 1002 NLQFVNETDSTVLVRWTPPRAQITGYRLTVG-LTRRGQPRQYNVGPSVSKYPLRNLQPAS 1060
            NL   +ET  ++ V WTPP  ++  Y LT    +  G  +  +V  + S   L +LQ A+
Sbjct: 746  NLALASETPDSLQVSWTPPLGRVLHYWLTYAPASGLGPEKSVSVPGARSHVTLPDLQAAT 805

Query: 1061 EYTVSLVAI--KGNQESPKATG--VFTTLQPGSSIPPYNTEV 1098
            +Y V + AI   G  E+  ATG      L+P  S+P ++  V
Sbjct: 806  KYRVLVSAIYAAGRSEAVSATGQTACPALRPDGSLPGFDLMV 847



 Score = 74.7 bits (182), Expect = 1e-12
 Identities = 92/414 (22%), Positives = 159/414 (38%), Gaps = 34/414 (8%)

Query: 590 YGRGIGEWHCQPLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSH-ISKYILRWRPK 648
           Y  G+GE     + T P    P    +T     P +  + W   QPS   + Y++R  P 
Sbjct: 450 YEGGVGEGLRGLVTTAPL---PPPRALTLAAVTPRTVHLTW---QPSAGATHYLVRCSPA 503

Query: 649 NSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTS 708
           +  G  +E  +        + GL+PG  YE  + S++     E       T + + P   
Sbjct: 504 SPKGEEEEREVQVGRPEVLLDGLEPGRDYEVSVQSLRGPEGSEARGIRARTPTLAPP--- 560

Query: 709 NTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDL 768
                               ++++  +  V W  A   V   RV Y  SE G   Q  + 
Sbjct: 561 ---------------RHLGFSDVSHDAARVFWEGAPRPVRLVRVTYVSSEGGHSGQ-TEA 604

Query: 769 PSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIV 828
           P  ATS  +  L     Y V V  +   G  S +     T    +P   ++ ++   ++ 
Sbjct: 605 PGNATSATLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVTTKKAPSPSQLSMTELPGDAVQ 664

Query: 829 VRW-SRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYA-VEEN 886
           + W +   + +  Y+I ++P  EG + E+++P    +  L  L    +Y++TI A   + 
Sbjct: 665 LAWVAAAPSGVLVYQITWTPLGEGKAHEISVPGNLGTAVLPGLGRHTEYDVTILAYYRDG 724

Query: 887 QESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVN- 945
             S PV ++     TP + +   P +L     T   + + WTPP   V  Y +   P + 
Sbjct: 725 ARSDPVSLRY----TPSTVSRSPPSNLALASETPDSLQVSWTPPLGRVLHYWLTYAPASG 780

Query: 946 LPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDA 999
           L  E    +P +R +   +  L     Y   V A+     S+ ++A   T   A
Sbjct: 781 LGPEKSVSVPGAR-SHVTLPDLQAATKYRVLVSAIYAAGRSEAVSATGQTACPA 833



 Score = 65.5 bits (158), Expect = 6e-10
 Identities = 66/271 (24%), Positives = 113/271 (41%), Gaps = 23/271 (8%)

Query: 604 TYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHL 663
           T   +  P ++ +TE P   ++  + W A  PS +  Y + W P    G+  E ++PG+L
Sbjct: 643 TTKKAPSPSQLSMTELPG--DAVQLAWVAAAPSGVLVYQITWTPLGE-GKAHEISVPGNL 699

Query: 664 NSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVA 723
            +  + GL     Y+  +++  + G +        +   S   T +TV+   +P S L  
Sbjct: 700 GTAVLPGLGRHTEYDVTILAYYRDGAR--------SDPVSLRYTPSTVS--RSPPSNLAL 749

Query: 724 TSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPG 783
            SE     T  S  VSW      V  + + Y  +      + + +P   + V +PDL   
Sbjct: 750 ASE-----TPDSLQVSWTPPLGRVLHYWLTYAPASGLGPEKSVSVPGARSHVTLPDLQAA 804

Query: 784 RKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYR- 842
            KY V V  I   G    + +T QT  P   PD ++   D   ++V +S  +      R 
Sbjct: 805 TKYRVLVSAIYAAGRSEAVSATGQTACPALRPDGSLPGFD---LMVAFSLVEKAYASIRG 861

Query: 843 IVYSPSVEGSSTELNLPETAN-SVTLSDLQP 872
           +   PS  G +    L + A  +  +SD+ P
Sbjct: 862 VAMEPSAFGGTPTFTLFKDAQLTRRVSDVYP 892



 Score = 46.2 bits (108), Expect = 4e-04
 Identities = 54/239 (22%), Positives = 77/239 (32%), Gaps = 56/239 (23%)

Query: 1891 RSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQP-PRARITGYIIKYEKPGSPPREVVP 1949
            R  P    A   + AP++L     T +S+ +SW P PR  +   I+     G  PREVV 
Sbjct: 365  RQGPAAAPALDTLPAPTSLVLSQVTSSSIRLSWTPAPRHPLKYLIVWRASRGGTPREVVV 424

Query: 1950 RPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQKTPFVTHPGYDTGNGI 2009
                  TE  +  L   TEY + V                           P Y+ G G 
Sbjct: 425  EGPAASTE--LHNLASRTEYLVSVF--------------------------PIYEGGVGE 456

Query: 2010 QLPGTSGQQPSVGQQMIFEEHGFRRTTPPTTATPIRHRPRPYPPNVGQEALSQTTISWAP 2069
             L G     P                 PP   T     PR               ++W P
Sbjct: 457  GLRGLVTTAP---------------LPPPRALTLAAVTPRT------------VHLTWQP 489

Query: 2070 FQDTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHKVR 2128
                + Y++ C P     E  +  V        L GL  G  Y + V++L+  +  + R
Sbjct: 490  SAGATHYLVRCSPASPKGEEEEREVQVGRPEVLLDGLEPGRDYEVSVQSLRGPEGSEAR 548


>gi|110349719 titin isoform N2-A [Homo sapiens]
          Length = 33423

 Score =  154 bits (388), Expect = 1e-36
 Identities = 299/1365 (21%), Positives = 509/1365 (37%), Gaps = 169/1365 (12%)

Query: 590   YGRGIGEWHCQPLQTYPSSSGPVEVFITETPSQPNSHPI-QWNAPQP---SHISKYILRW 645
             YG G+     +P+    S + P    I E       H I QW  P+    + IS Y++  
Sbjct: 29220 YGPGVPV-ESEPIVARNSFTIPSPPGIPEEVGTGKEHIIIQWTKPESDGGNEISNYLVDK 29278

Query: 646   RPKNSVGRWKEATIPGHLNSYTIK--GLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTS 703
             R K S+ RW        +    +K   L  G  Y+ ++ ++   G+ E +          
Sbjct: 29279 REKKSL-RWTRVNKDYVVYDTRLKVTSLMEGCDYQFRVTAVNAAGNSEPSE--------- 29328

Query: 704   TPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELS-EEGDE 762
                 SN ++     ++P   ++  V + T  S  ++W           V Y L  +E D 
Sbjct: 29329 ---ASNFISCREPSYTPGPPSAPRVVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDT 29385

Query: 763   PQYLDLPSTATSVN----IPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPT 818
              Q+  + + AT  N    +PDL  G+KY   V  ++  G      S ++    +    P 
Sbjct: 29386 DQWYRVHTNATIRNTEFTVPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEIPD 29445

Query: 819   VDQVDDT--SIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLP-----ETANSVTLSDLQ 871
             ++  DD   ++ +R       +        P +  S   ++L      +T  S +L  + 
Sbjct: 29446 LELADDLKKTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAIIDTTESYSLLIVD 29505

Query: 872   PGVQYNITIYAVE-ENQE----STPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIM 926
                +Y+   Y +E ENQ     +T +V   +T G       P P  ++  EV+   VTI 
Sbjct: 29506 KVNRYDAGKYTIEAENQSGKKSATVLVKVYDTPG-------PCP-SVKVKEVSRDSVTIT 29557

Query: 927   WTPPE----SAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSH 982
             W  P     + V  Y V+     +          S+ T   ++GL  G  YYF+V   + 
Sbjct: 29558 WEIPTIDGGAPVNNYIVEKREAAMRAFKTVTTKCSK-TLYRISGLVEGTMYYFRVLPENI 29616

Query: 983   GRESKPLTAQQTTKLD----APTNLQFVNETDSTVLVRWTPPR----AQITGYRLTVGLT 1034
                 +P        +      P  L+ V+ T STV + W  P     +++TGY L     
Sbjct: 29617 YGIGEPCETSDAVLVSEVPLVPAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEA--C 29674

Query: 1035  RRGQPRQYNV---GPSVSKYPLRNLQPASEYTVSLVAI--KGNQESPKATGVFTTLQPGS 1089
             + G  R   V    P+V ++ + +L    +Y   + A   KG  E P+ T    T+Q   
Sbjct: 29675 KAGTERWMKVVTLKPTVLEHTVTSLNEGEQYLFRIRAQNEKGVSE-PRETVTAVTVQDLR 29733

Query: 1090  SIPPYNTEV-------------TETTIVITWTPAPRIG-FKLGVRPSQGGEAPREVTSDS 1135
              +P  +                 E  I I   P P    F  G +  +      E  +  
Sbjct: 29734 VLPTIDLSTMPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKV 29793

Query: 1136  GSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSW 1195
               + +   T      YT+++          I   ++    PPT        D   +T+SW
Sbjct: 29794 AKLTIRETTIRDTGEYTLELKNVTGTTSETIKVIILDKPGPPTGPIKIDEIDATSITISW 29853

Query: 1196  ERSTTPD---ITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSV----- 1247
             E         ++GY +     +      + E V   +S+  F  L+ G EY   V     
Sbjct: 29854 EPPELDGGAPLSGYVVEQRDAHRPGWLPVSESV--TRSTFKFTRLTEGNEYVFRVAATNR 29911

Query: 1248  YTVKDDKESVPISDTIIPAVP-PPTDLRFTNIGPDTMRVTWAPPPS---IDLTNFLVRYS 1303
             + +    +S  I       +P PP  L+  ++  D M +TW PP       +T ++V   
Sbjct: 29912 FGIGSYLQSEVIECRSSIRIPGPPETLQIFDVSRDGMTLTWYPPEDDGGSQVTGYIVERK 29971

Query: 1304  PVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLR-GRQKTGLD--- 1359
              V+ +  V    +  +      T L  G EY   V+++  +    P R  +    +D   
Sbjct: 29972 EVRADRWVRVNKVPVTMTRYRSTGLTEGLEYEHRVTAINARGSGKPSRPSKPIVAMDPIA 30031

Query: 1360  ---SPTGIDFSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRNS 1412
                 P     +D T  S ++ W  P     + +TGY I           + +  P     
Sbjct: 30032 PPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTKCNTTPTKIRE 30091

Query: 1413  ITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAAT--PTSLLISWDA 1470
              TLT+L  G EY   ++A N         G     ++VP  ++V      P   L     
Sbjct: 30092 YTLTHLPQGAEYRFRVLACNA--------GGPGEPAEVPGTVKVTEMLEYPDYELDERYQ 30143

Query: 1471  PAVTVRY---YRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDS 1527
               + VR     R+T    G   P+ ++T  G +  +  + +     +T  V     RGDS
Sbjct: 30144 EGIFVRQGGVIRLTIPIKGKPFPICKWTKEG-QDISKRAMIATSETHTELVIKEADRGDS 30202

Query: 1528  ---------PASSKPISINYRTEIDKPSQ----MQVTDVQDNSISVKWLPSS----SPVT 1570
                          K + I  R  I  P+     ++  D+Q  S+ V W P +    + + 
Sbjct: 30203 GTYDLVLENKCGKKAVYIKVRV-IGSPNSPEGPLEYDDIQVRSVRVSWRPPADDGGADIL 30261

Query: 1571  GYRVTT--TPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQ-- 1626
             GY +     PK       ++  G   T + ++GL+  VEY   V A+N  G S+PL    
Sbjct: 30262 GYILERREVPKAAWYTIDSRVRG---TSLVVKGLKENVEYHFRVSAENQFGISKPLKSEE 30318

Query: 1627  --TAVTNIDRPKGLA----FTDVDVDSIKIAWESPQGQ-VSRYRVTYSSPEDGIHELFPA 1679
               T  T ++ P+  +      DV   S+ ++W  P+    SR    Y   ++   + +  
Sbjct: 30319 PVTPKTPLNPPEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRVTGYYIERKETSTDKWVR 30378

Query: 1680  PDGEEDTAEL---QGLRPGSEYTVSVVALHD------DMESQPLIGTQSTAIPA-PTDLK 1729
              +  + T  +    GL P +EY   ++A +D         S+P++       P+ P +L+
Sbjct: 30379 HNKTQITTTMYTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCKDPFDKPSQPGELE 30438

Query: 1730  FTQVTPTSLSAQWTPPNV----QLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVA 1785
                ++  S++ QW  P      ++ GY V       +   K            + GL+ A
Sbjct: 30439 ILSISKDSVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERIKDKQFTIGGLLEA 30498

Query: 1786  TKYEVSVYALKDTLTSRP---AQGVVTTL-ENVSPPRRARVTDAT 1826
             T+YE  V+A  +T  SRP   A  + T L    +P  R  + D T
Sbjct: 30499 TEYEFRVFAENETGLSRPRRTAMSIKTKLTSGEAPGIRKEMKDVT 30543



 Score =  148 bits (373), Expect = 7e-35
 Identities = 289/1429 (20%), Positives = 524/1429 (36%), Gaps = 170/1429 (11%)

Query: 696   DFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYE 755
             D+T T+ ++  + +          P    S  + ++ +   ++SW    +        Y 
Sbjct: 19365 DYTITAENSSGSKSATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYI 19424

Query: 756   LSE-EGDEPQYLDLPSTA--TSVNIPDLLPGRKY-----IVNVYQISEDGEQSLILSTSQ 807
             + + E   P +  + +T   TS ++  L+ G +Y       N Y + +       ++ + 
Sbjct: 19425 VDKRETSRPNWAQVSATVPITSCSVEKLIEGHEYQFRICAENKYGVGDPVFTEPAIAKNP 19484

Query: 808   TTAPDAPPDPTVDQVDDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNL-PETA 862
                P     P +  +    + V W  P     +PITGY +    +   + T++N  P   
Sbjct: 19485 YDPPGRCDPPVISNITKDHMTVSWKPPADDGGSPITGYLLEKRETQAVNWTKVNRKPIIE 19544

Query: 863   NSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVK 922
              ++  + LQ G +Y   + A+ +     P    +             P   +  + T   
Sbjct: 19545 RTLKATGLQEGTEYEFRVTAINKAGPGKPSDASKAAYARDPQYPPGPPAFPKVYDTTRSS 19604

Query: 923   VTIMWTPPE----SAVTGYRVDVIPVNLPGEHGQRLPIS-RNTFAEVTGLSPGVTYYFKV 977
             V++ W  P     S + GY V+V   +        LP + + T  EVTGL     Y F+V
Sbjct: 19605 VSLSWGKPAYDGGSPIIGYLVEVKRADSDNWVRCNLPQNLQKTRFEVTGLMEDTQYQFRV 19664

Query: 978   FAVSHGRESKP-----------LTAQQTTKLDAPTNLQFVNETDST----VLVRWTPPRA 1022
             +AV+    S P           +      +LDA      +     T    V V+  PP  
Sbjct: 19665 YAVNKIGYSDPSDVPDKHYPKDILIPPEGELDADLRKTLILRAGVTMRLYVPVKGRPP-P 19723

Query: 1023  QITGYRLTVGLTRR-GQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGV 1081
             +IT  +  V L  R G   +     +  +    N   A +Y ++L    G +E      V
Sbjct: 19724 KITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKYILTLENSCGKKEYTIVVKV 19783

Query: 1082  FTTLQPGSSIPPYNTEVTETTIVITWTP------APRIGFKLGVRPSQGGEAPREVTSDS 1135
               T  PG  +     E+++ +  +TW P      +P I + +  R ++        T  S
Sbjct: 19784 LDT--PGPPVNVTVKEISKDSAYVTWEPPIIDGGSPIINYVVQKRDAERKSWSTVTTECS 19841

Query: 1136  G-SIVVSGLTPGVEYVYTIQVLRD------GQERDAPIVNKVVTPLSPPTNLHLEANPDT 1188
               S  V+ L  G  Y + +    +      G+ RDA  V    TP  P  +L + +   +
Sbjct: 19842 KTSFRVANLEEGKSYFFRVFAENEYGIGDPGETRDA--VKASQTP-GPVVDLKVRSVSKS 19898

Query: 1189  GVLTVSWERSTTPD---ITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNV 1245
                ++ W++  +     I GY +        + N  + V+ +     +  +L+ G EY  
Sbjct: 19899 SC-SIGWKKPHSDGGSRIIGYVVDFLT----EENKWQRVMKSLSLQYSAKDLTEGKEYTF 19953

Query: 1246  SVYTVKDDKESVPISDTIIP---AVPPPTDLRFTNIGPDT-------------MRVTWAP 1289
              V    ++ E  P   T++     V P  DL+     PD              + +   P
Sbjct: 19954 RVSAENENGEGTPSEITVVARDDVVAPDLDLKGL---PDLCYLAKENSNFRLKIPIKGKP 20010

Query: 1290  PPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLL-------PGTEYVVSVSSVY 1342
              PS+         S  K E+ +A  +    +++ V T L+          +Y +++ +V 
Sbjct: 20011 APSV---------SWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVA 20061

Query: 1343  EQHEST-PLRGRQKTGLDSPTG-IDFSDITANSFTVHWIAPR----ATITGYRIRHHPEH 1396
                E T  ++   K G+  PTG I F ++TA + T+ W  P+    + IT Y I    + 
Sbjct: 20062 GTKEGTISIKVVGKPGI--PTGPIKFDEVTAEAMTLKWAPPKDDGGSEITNY-ILEKRDS 20118

Query: 1397  FSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN------GREESPLLIGQQSTVSDV 1450
              + +         + +  +T L  G EY   + A N      G +  P++      V D 
Sbjct: 20119 VNNKWVTCASAVQKTTFRVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVPDA 20178

Query: 1451  PRDLEVVAATPTSLLISWDAPAVT----VRYYRITYGETGGNSPVQEFTVPGSKSTATIS 1506
             P    +V     S+ ++W  P  T    +  Y + + E       +    P       ++
Sbjct: 20179 PPPPNIVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTPIRMRDFKVT 20238

Query: 1507  GLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLP-- 1564
             GL  G++Y   V A+   G    S     +     ID P + +V ++  NS+++ W    
Sbjct: 20239 GLTEGLEYEFRVMAINLAGVGKPSLPSEPVVALDPIDPPGKPEVINITRNSVTLIWTEPK 20298

Query: 1565  --SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQ 1622
                   +TGY V           K       +   T+  L    +Y   + A+N +G   
Sbjct: 20299 YDGGHKLTGYIVEKRDLPSKSWMKANHVNVPECAFTVTDLVEGGKYEFRIRAKNTAGAIS 20358

Query: 1623  PLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQV----------------SRYRVTY 1666
                ++  T I + +  A T V   +IK       G                  S  +   
Sbjct: 20359 APSESTETIICKDEYEAPTIVLDPTIKDGLTIKAGDTIVLNAISILGKPLPKSSWSKAGK 20418

Query: 1667  SSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPT 1726
                   I ++   P     T +    +   EYT++             +       P P 
Sbjct: 20419 DIRPSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFGTKVEHVKVTVLDVPGP-PG 20477

Query: 1727  DLKFTQVTPTSLSAQWTPPNVQLTGYRVR--VTPKEKTGPMKEINLAPDSSSV--VVSGL 1782
              ++ + V+    +  WTPP ++  G  ++  +  K +T  +    ++ D  S   V + L
Sbjct: 20478 PVEISNVSAEKATLTWTPP-LEDGGSPIKSYILEKRETSRLLWTVVSEDIQSCRHVATKL 20536

Query: 1783  MVATKYEVSVYALKDTLTSRPAQG----VVTTLENVSPPRRARVTDATETTITISWRTKT 1838
             +   +Y   V A+       P Q     +V       PP +  V++ T+ T T+SW+   
Sbjct: 20537 IQGNEYIFRVSAVNHYGKGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSWKRPV 20596

Query: 1839  E----TITGFQVDAVPANGQTPIQRTIKPDVRSY--TITGLQPGTDYKIYLYTLN----- 1887
             +     ITG+ V+         + R IK  V      +TGLQ G+ Y+  +   N     
Sbjct: 20597 DDGGSEITGYHVERREKKSLRWV-RAIKTPVSDLRCKVTGLQEGSTYEFRVSAENRAGIG 20655

Query: 1888  --DNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPG 1941
                 A  S ++ DA+     PSN     TT  S  ++W  P       ITGY+++++K G
Sbjct: 20656 PPSEASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLAWGKPHYDGGLEITGYVVEHQKVG 20715

Query: 1942  SPPREVVPRPRPG----VTEATITGLEPGTEYTIYVIALKNNQKSEPLI 1986
                 E   +   G    +T+  +  L+   +Y   + A+ +    EP +
Sbjct: 20716 D---EAWIKDTTGTALRITQFVVPDLQTKEKYNFRISAINDAGVGEPAV 20761



 Score =  146 bits (368), Expect = 3e-34
 Identities = 299/1392 (21%), Positives = 517/1392 (37%), Gaps = 202/1392 (14%)

Query: 780   LLPGRKYIVNVYQISEDG-----EQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRP 834
             L+   +YI  V  +++ G     E   I++ +  T P  P  P         I+++W++P
Sbjct: 29204 LIKNNEYIFRVRAVNKYGPGVPVESEPIVARNSFTIPSPPGIPEEVGTGKEHIIIQWTKP 29263

Query: 835   QAP----ITGYRIVYSPSVEGSSTELNLPETANSVTL--SDLQPGVQYNITIYAVEENQE 888
             ++     I+ Y +          T +N         L  + L  G  Y   + AV     
Sbjct: 29264 ESDGGNEISNYLVDKREKKSLRWTRVNKDYVVYDTRLKVTSLMEGCDYQFRVTAVNAAGN 29323

Query: 889   STPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPV 944
             S P       +    S T   P   + V+ T   +++ WT P     + + GY +++   
Sbjct: 29324 SEPSEASNFISCREPSYTPGPPSAPRVVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEK 29383

Query: 945   NLPGEHGQRLPIS-RNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTA----QQTTKLDA 999
             +    +      + RNT   V  L  G  Y F+V AV+    S+   +    +   +++ 
Sbjct: 29384 DTDQWYRVHTNATIRNTEFTVPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEI 29443

Query: 1000  PTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQP-----------RQYNVGPSV 1048
             P +L+  ++   TV +R           RL V ++ R  P               +  + 
Sbjct: 29444 P-DLELADDLKKTVTIRAG------ASLRLMVSVSGRPPPVITWSKQGIDLASRAIIDTT 29496

Query: 1049  SKYPLR-----NLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTI 1103
               Y L      N   A +YT+      G + +     V+ T  P  S+     EV+  ++
Sbjct: 29497 ESYSLLIVDKVNRYDAGKYTIEAENQSGKKSATVLVKVYDTPGPCPSVKV--KEVSRDSV 29554

Query: 1104  VITWT------PAPRIGFKLGVRPSQGGEAPREVTSDSGSIV-VSGLTPGVEYVYTIQ-- 1154
              ITW        AP   + +  R +         T  S ++  +SGL  G  Y + +   
Sbjct: 29555 TITWEIPTIDGGAPVNNYIVEKREAAMRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPE 29614

Query: 1155  ----VLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPD---ITGYR 1207
                 +    +  DA +V++V  PL P     ++    T  +T++WE+        +TGY 
Sbjct: 29615 NIYGIGEPCETSDAVLVSEV--PLVPAKLEVVDVTKST--VTLAWEKPLYDGGSRLTGYV 29670

Query: 1208  ITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEY-----------------NVSVYTV 1250
             +       ++   +   +       T  +L+ G +Y                  V+  TV
Sbjct: 29671 LEACKAGTERWMKVV-TLKPTVLEHTVTSLNEGEQYLFRIRAQNEKGVSEPRETVTAVTV 29729

Query: 1251  KD-------DKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYS 1303
             +D       D  ++P     +PA   P +L         + +   PPP+     F     
Sbjct: 29730 QDLRVLPTIDLSTMPQKTIHVPA-GRPVEL--------VIPIAGRPPPAASW--FFAGSK 29778

Query: 1304  PVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVY-EQHESTPLRGRQKTGLDSPT 1362
               ++E    E     +   +  T +    EY + + +V     E+  +    K G   PT
Sbjct: 29779 LRESERVTVETHTKVAKLTIRETTIRDTGEYTLELKNVTGTTSETIKVIILDKPG--PPT 29836

Query: 1363  G-IDFSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSG-RPREDRVPHSRNSITLT 1416
             G I   +I A S T+ W  P     A ++GY +     H  G  P  + V  +R++   T
Sbjct: 29837 GPIKIDEIDATSITISWEPPELDGGAPLSGYVVEQRDAHRPGWLPVSESV--TRSTFKFT 29894

Query: 1417  NLTPGTEYVVSIVALN----GREESPLLIGQQSTVS--DVPRDLEVVAATPTSLLISWDA 1470
              LT G EYV  + A N    G      +I  +S++     P  L++   +   + ++W  
Sbjct: 29895 RLTEGNEYVFRVAATNRFGIGSYLQSEVIECRSSIRIPGPPETLQIFDVSRDGMTLTWYP 29954

Query: 1471  P----AVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGD 1526
             P       V  Y +   E   +  V+   VP + +    +GL  G++Y   V A+  RG 
Sbjct: 29955 PEDDGGSQVTGYIVERKEVRADRWVRVNKVPVTMTRYRSTGLTEGLEYEHRVTAINARGS 30014

Query: 1527  SPAS--SKPI-SINYRTEIDKPSQMQVTDVQDNSISVKWL----PSSSPVTGYRVTTTPK 1579
                S  SKPI +++      KP   +VTD    S+S+ W        S VTGY +     
Sbjct: 30015 GKPSRPSKPIVAMDPIAPPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKV 30074

Query: 1580  NGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLA 1639
             +    TK  T      E T+  L    EY   V A N  G  +P        +     L 
Sbjct: 30075 DQHEWTKCNTTPTKIREYTLTHLPQGAEYRFRVLACNAGGPGEPAEVPGTVKVTEM--LE 30132

Query: 1640  FTDVDVDS-IKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEY 1698
             + D ++D   +      QG V R  +        I +     +G+ D ++   +     +
Sbjct: 30133 YPDYELDERYQEGIFVRQGGVIRLTIPIKGKPFPICKW--TKEGQ-DISKRAMIATSETH 30189

Query: 1699  TVSVVALHDDMES------------QPLIGTQSTAIPAPTD----LKFTQVTPTSLSAQW 1742
             T  V+   D  +S            +  +  +   I +P      L++  +   S+   W
Sbjct: 30190 TELVIKEADRGDSGTYDLVLENKCGKKAVYIKVRVIGSPNSPEGPLEYDDIQVRSVRVSW 30249

Query: 1743  TPP----NVQLTGYRV--RVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALK 1796
              PP       + GY +  R  PK        I+     +S+VV GL    +Y   V A  
Sbjct: 30250 RPPADDGGADILGYILERREVPK---AAWYTIDSRVRGTSLVVKGLKENVEYHFRVSAEN 30306

Query: 1797  DTLTSRP--AQGVVTTLENVSPPRRA----RVTDATETTITISW-RTKTE---TITGFQV 1846
                 S+P  ++  VT    ++PP        V D T++++++SW R K +    +TG+ +
Sbjct: 30307 QFGISKPLKSEEPVTPKTPLNPPEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRVTGYYI 30366

Query: 1847  DAVPANGQTPIQRTIKPDVRS--YTITGLQPGTDYKIYLYTLND------NARSSPVVI- 1897
             +    +    ++   K  + +  YT+TGL P  +Y+  +   ND      +  S PVV  
Sbjct: 30367 ERKETSTDKWVRHN-KTQITTTMYTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCK 30425

Query: 1898  DASTAIDAPSNLRFLATTPNSLLVSWQPPRA----RITGYIIKYEKPGSPPREVVPRPRP 1953
             D       P  L  L+ + +S+ + W+ P       I GY ++Y + G    +   + R 
Sbjct: 30426 DPFDKPSQPGELEILSISKDSVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERI 30485

Query: 1954  GVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQKTPFVTHPGYDTGNGIQLPG 2013
                + TI GL   TEY   V A      S P                    T   I+   
Sbjct: 30486 KDKQFTIGGLLEATEYEFRVFAENETGLSRP------------------RRTAMSIKTKL 30527

Query: 2014  TSGQQPSVGQQM 2025
             TSG+ P + ++M
Sbjct: 30528 TSGEAPGIRKEM 30539



 Score =  134 bits (338), Expect = 8e-31
 Identities = 286/1432 (19%), Positives = 516/1432 (36%), Gaps = 199/1432 (13%)

Query: 728   VTEITASSFVVSWVSASDTVSGFRVEY--ELSEEGDEP-QYLDLPSTATSVNIPDLLPGR 784
             V+ ++A S V+SW    D        Y  E  E G    Q ++     T + +  L    
Sbjct: 28750 VSSVSAESCVLSWGEPKDGGGTEITNYIVEKRESGTTAWQLVNSSVKRTQIKVTHLTKYM 28809

Query: 785   KYIVNV-----YQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPIT 839
             +Y   V     + +S+  E + I++      P AP  P V  V   ++ +RW  P     
Sbjct: 28810 EYSFRVSSENRFGVSKPLESAPIIAEHPFVPPSAPTRPEVYHVSANAMSIRWEEPYHDGG 28869

Query: 840   GYRIVYSPSVEGSST-----ELNLPETANSVTLSDLQPGVQYNITIYAV------EENQE 888
                I Y    +  +T     E  +P    +  ++ L  G++Y    YA+      + ++ 
Sbjct: 28870 SKIIGYWVEKKERNTILWVKENKVPCLECNYKVTGLVEGLEYQFRTYALNAAGVSKASEA 28929

Query: 889   STPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPV 944
             S P++ Q         + V +P   +  +VT   V+++W+ P     S V GY ++  PV
Sbjct: 28930 SRPIMAQ---------NPVDAPGRPEVTDVTRSTVSLIWSAPAYDGGSKVVGYIIERKPV 28980

Query: 945   NLPGEHGQRLP----ISRNTFAEVTGLSPGVTYYFKVFA------VSHGRESK-PLT--- 990
             +  G+ G+ L     I  + F  VT LS G TY F+V A      +S G ES  P+T   
Sbjct: 28981 SEVGD-GRWLKCNYTIVSDNFFTVTALSEGDTYEFRVLAKNAAGVISKGSESTGPVTCRD 29039

Query: 991   --AQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPR-------- 1040
               A    +LDA  +   V     + LV      A + G      +  +G           
Sbjct: 29040 EYAPPKAELDARLHGDLVTIRAGSDLVL----DAAVGGKPEPKIIWTKGDKELDLCEKVS 29095

Query: 1041  -QYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTL--QPGSSIPPYNTE 1097
              QY    + +     +   + +YT+++     N    KA  V   +   PG       + 
Sbjct: 29096 LQYTGKRATAVIKFCDRSDSGKYTLTVK----NASGTKAVSVMVKVLDSPGPCGKLTVSR 29151

Query: 1098  VTETTIVITWTPAPRIGFKLGVRPSQGGEAP-------REVTSDSGSIVVSGLTPGVEYV 1150
             VT+    + W+            P + G A        R  TS    ++V G  P + YV
Sbjct: 29152 VTQEKCTLAWS-----------LPQEDGGAEITHYIVERRETSRLNWVIVEGECPTLSYV 29200

Query: 1151  YTIQVLRDGQE----------------RDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVS 1194
              T +++++ +                    PIV +    +  P  +  E       + + 
Sbjct: 29201 VT-RLIKNNEYIFRVRAVNKYGPGVPVESEPIVARNSFTIPSPPGIPEEVGTGKEHIIIQ 29259

Query: 1195  WERSTTP---DITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVK 1251
             W +  +    +I+ Y +        +   + +      +     +L  G +Y   V  V 
Sbjct: 29260 WTKPESDGGNEISNYLVDKREKKSLRWTRVNKDYVVYDTRLKVTSLMEGCDYQFRVTAVN 29319

Query: 1252  DDKESVP--ISDTIIPAVP-----PPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSP 1304
                 S P   S+ I    P     PP+  R  +    ++ + W  P   D    +V Y  
Sbjct: 29320 AAGNSEPSEASNFISCREPSYTPGPPSAPRVVDTTKHSISLAWTKP-MYDGGTDIVGYVL 29378

Query: 1305  VKNEEDVAE-----LSISPSDNAVVLTNLLPGTEYVVSVSSV----YEQHESTPLRGRQK 1355
                E+D  +      + +  +    + +L  G +Y   V++V      ++  +       
Sbjct: 29379 EMQEKDTDQWYRVHTNATIRNTEFTVPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPV 29438

Query: 1356  TGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVP-------- 1407
               ++ P  ++ +D    + T+   A    +     R  P     +   D           
Sbjct: 29439 ERIEIPD-LELADDLKKTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAIIDTTE 29497

Query: 1408  -HSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLI 1466
              +S   +   N     +Y +     +G++ + +L+    T    P  ++V   +  S+ I
Sbjct: 29498 SYSLLIVDKVNRYDAGKYTIEAENQSGKKSATVLVKVYDTPGPCP-SVKVKEVSRDSVTI 29556

Query: 1467  SWDAPAVT----VRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYA-- 1520
             +W+ P +     V  Y +   E    +  +  T   SK+   ISGL  G  Y   V    
Sbjct: 29557 TWEIPTIDGGAPVNNYIVEKREAAMRA-FKTVTTKCSKTLYRISGLVEGTMYYFRVLPEN 29615

Query: 1521  VTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKW----LPSSSPVTGYRVTT 1576
             + G G+   +S  + ++    +  P++++V DV  +++++ W        S +TGY +  
Sbjct: 29616 IYGIGEPCETSDAVLVSEVPLV--PAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEA 29673

Query: 1577  TPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPK 1636
                      K  T  P   E T+  L    +Y+  + AQN  G S+P        +   +
Sbjct: 29674 CKAGTERWMKVVTLKPTVLEHTVTSLNEGEQYLFRIRAQNEKGVSEPRETVTAVTVQDLR 29733

Query: 1637  GLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDG--EEDTAELQGLRP 1694
              L   D+     K     P G+     +  +         F A     E +   ++    
Sbjct: 29734 VLPTIDLSTMPQKTI-HVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTK 29792

Query: 1695  GSEYTVSVVALHDD----MESQPLIGTQSTAI---------PAPTDLKFTQVTPTSLSAQ 1741
              ++ T+    + D     +E + + GT S  I         P    +K  ++  TS++  
Sbjct: 29793 VAKLTIRETTIRDTGEYTLELKNVTGTTSETIKVIILDKPGPPTGPIKIDEIDATSITIS 29852

Query: 1742  WTPPNVQ----LTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKD 1797
             W PP +     L+GY V      + G +      P S SV  S        E + Y  + 
Sbjct: 29853 WEPPELDGGAPLSGYVVEQRDAHRPGWL------PVSESVTRSTFKFTRLTEGNEYVFRV 29906

Query: 1798  TLTSRPAQGVVTTLENVS---------PPRRARVTDATETTITISWRTKTET----ITGF 1844
               T+R   G     E +          PP   ++ D +   +T++W    +     +TG+
Sbjct: 29907 AATNRFGIGSYLQSEVIECRSSIRIPGPPETLQIFDVSRDGMTLTWYPPEDDGGSQVTGY 29966

Query: 1845  QVDAVPANGQTPIQRTIKP-DVRSYTITGLQPGTDYKIYLYTLNDNARSSP-------VV 1896
              V+         ++    P  +  Y  TGL  G +Y+  +  +N      P       V 
Sbjct: 29967 IVERKEVRADRWVRVNKVPVTMTRYRSTGLTEGLEYEHRVTAINARGSGKPSRPSKPIVA 30026

Query: 1897  IDASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREVVPRPR 1952
             +D       P N R   TT  S+ ++W  P     +++TGY+I+ +K             
Sbjct: 30027 MDPIAPPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTKCNTTP 30086

Query: 1953  PGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQKTPFVTHPGYD 2004
               + E T+T L  G EY   V+A       EP      TV+ T  + +P Y+
Sbjct: 30087 TKIREYTLTHLPQGAEYRFRVLACNAGGPGEP-AEVPGTVKVTEMLEYPDYE 30137



 Score =  132 bits (333), Expect = 3e-30
 Identities = 291/1351 (21%), Positives = 478/1351 (35%), Gaps = 186/1351 (13%)

Query: 771   TATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVR 830
             T  S++  D     KYI+ +   S  G +S  ++      P  P +  V +V   S  + 
Sbjct: 24078 TQLSIDNCDRNDAGKYILKLENSS--GSKSAFVTVKVLDTPGPPQNLAVKEVRKDSAFLV 24135

Query: 831   WSRP----QAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEEN 886
             W  P     A +  Y I    S   +   ++   +  S  + +L  G  Y   + A  E 
Sbjct: 24136 WEPPIIDGGAKVKNYVIDKRESTRKAYANVSSKCSKTSFKVENLTEGAIYYFRVMAENEF 24195

Query: 887   QESTPVVIQQETTGTPRSDTVPSPRD-LQFVEVTDVKVTIMWTPPE----SAVTGYRVDV 941
                 PV    ET    ++   PSP   +   +V+    ++MW  PE    S V GY V++
Sbjct: 24196 GVGVPV----ETVDAVKAAEPPSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVEM 24251

Query: 942   IPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKP-----------LT 990
              P     E    +  S+   A VTGLS G  Y F+V A +   +S P           LT
Sbjct: 24252 QPKGT--EKWSIVAESKVCNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLT 24309

Query: 991   AQQTTKLDAPT-NLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQP----RQYNVG 1045
              Q + KL   T ++Q   +    + V   P        R  +   + G+P     + NV 
Sbjct: 24310 IQPSLKLPFNTYSIQAGEDLKIEIPVIGRP--------RPNISWVKDGEPLKQTTRVNVE 24361

Query: 1046  PSVSKYPLR----NLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYN-TEVTE 1100
              + +   L     N     +YTV+     G   + +   V    +PG  + P    EV+ 
Sbjct: 24362 ETATSTVLHIKEGNKDDFGKYTVTATNSAGT--ATENLSVIVLEKPGPPVGPVRFDEVSA 24419

Query: 1101  TTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIV----------VSGLTPGVEYV 1150
               +VI+W P    G   G + S      R+ T+ +  +V          ++ L  G EY 
Sbjct: 24420 DFVVISWEPPAYTG---GCQISNYIVEKRDTTTTTWHMVSATVARTTIKITKLKTGTEYQ 24476

Query: 1151  YTIQVLRDGQERDAPIVNKVVTPLSP-----PTNLHLEANPDTGVLTVSWERSTTPD--- 1202
             + I    +   + AP+ +K V    P     P       +     + V W          
Sbjct: 24477 FRI-FAENRYGKSAPLDSKAVIVQYPFKEPGPPGTPFVTSISKDQMLVQWHEPVNDGGTK 24535

Query: 1203  ITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYN--VSVYTVKDDKESVPIS 1260
             I GY +     N      L +    D    T   L  GLEY   VS   +    +   +S
Sbjct: 24536 IIGYHLEQKEKNSILWVKLNKTPIQDTKFKT-TGLDEGLEYEFKVSAENIVGIGKPSKVS 24594

Query: 1261  DTIIPAVP--PPTDLRFTNIGPDTMRVTWAPPP---SIDLTNFLVRYSPVKNEEDVAELS 1315
             +  +   P  PP       I  + + + W  P       +T ++V     K+  D   + 
Sbjct: 24595 ECFVARDPCDPPGRPEAIVITRNNVTLKWKKPAYDGGSKITGYIVEK---KDLPDGRWMK 24651

Query: 1316  ISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFT 1375
              S        TN+L  TE+ VS   V +Q     +  R   G  S        ITA    
Sbjct: 24652 AS-------FTNVLE-TEFTVS-GLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARD-- 24700

Query: 1376  VHWIAPRATITG-YR---IRHHPEHF------SGRPREDRV--------------PHSRN 1411
                 AP A++   Y+   + H  E F       G+P  D V                 ++
Sbjct: 24701 -EIDAPNASLDPKYKDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKS 24759

Query: 1412  SITLTNL-------TPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSL 1464
             +I  T L       T G +Y++ +  + G +  P+ +            L+V   T    
Sbjct: 24760 TIQKTTLVVKDCIRTDGGQYILKLSNVGGTKSIPITVKVLDRPGPPEGPLKVTGVTAEKC 24819

Query: 1465  LISWDAP----AVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYA 1520
              ++W+ P       + +Y I   ET   S  Q  T   + +   ++ L PG +Y   V A
Sbjct: 24820 YLAWNPPLQDGGANISHYIIEKRETSRLSWTQVSTEVQALNYK-VTKLLPGNEYIFRVMA 24878

Query: 1521  VTGRG-DSPASSKPISI-NYRTEIDKPSQMQVTDVQDNSISVKWL----PSSSPVTGYRV 1574
             V   G   P  S P++  N       PS  +V+ +  +S+ V W        + + GY +
Sbjct: 24879 VNKYGIGEPLESGPVTACNPYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYIL 24938

Query: 1575  TTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQT------- 1627
                 K G   TK          + + GL     Y   V A+N +G  +P   +       
Sbjct: 24939 EKRDKEGVRWTKCNKKTLTDLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRACD 24998

Query: 1628  AVTNIDRPKGLAFTDVDVDSIKIAWESP----QGQVSRYRVTYSSPEDGIHELFPAPDGE 1683
             A+     P     TD    S+ +AW  P       V  Y V               P G 
Sbjct: 24999 ALYPPGPPSNPKVTDTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAADEWTTCTPPTGL 25058

Query: 1684  EDTA-ELQGLRPGSEYTVSVVALHDDMESQPL-----IGTQSTAIPAPTDLKFTQVTPTS 1737
             +     +  L+  +EY   + A++ +   +P      +  Q    P   +L         
Sbjct: 25059 QGKQFTVTKLKENTEYNFRICAINSEGVGEPATLPGSVVAQERIEPPEIELDADLRKVVV 25118

Query: 1738  LSAQWTPPNVQLTGYRVRVTPKEKTGPM----KEINLAPDSSSVVVSGLMV------ATK 1787
             L A  T         R+ VT K +  P     K   +  D + + V+           T+
Sbjct: 25119 LRASAT--------LRLFVTIKGRPEPEVKWEKAEGILTDRAQIEVTSSFTMLVIDNVTR 25170

Query: 1788  YEVSVY--ALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKT----ETI 1841
             ++   Y   L++   S+ A   V  L++ S P    + +  + ++T+SW          I
Sbjct: 25171 FDSGRYNLTLENNSGSKTAFVNVRVLDSPSAPVNLTIREVKKDSVTLSWEPPLIDGGAKI 25230

Query: 1842  TGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDAST 1901
             T + V+      +     T      ++ I  LQ G  Y   +   N+     P       
Sbjct: 25231 TNYIVEKRETTRKAYATITNNCTKTTFRIENLQEGCSYYFRVLASNEYGIGLPAETTEPV 25290

Query: 1902  AIDAP----SNLRFLATTPNSLLVSWQPPRA----RITGYIIKYEKPGSPPREVVPRPRP 1953
              +  P      +  +  T N+  + W+ P +    +ITGY+++ +  GS       + + 
Sbjct: 25291 KVSEPPLPPGRVTLVDVTRNTATIKWEKPESDGGSKITGYVVEMQTKGSEKWSTCTQVK- 25349

Query: 1954  GVTEATITGLEPGTEYTIYVIALKNNQKSEP 1984
                EATI+GL  G EY   V A+    +S+P
Sbjct: 25350 -TLEATISGLTAGEEYVFRVAAVNEKGRSDP 25379



 Score =  132 bits (332), Expect = 4e-30
 Identities = 282/1282 (21%), Positives = 484/1282 (37%), Gaps = 198/1282 (15%)

Query: 611   PVEVFITETPSQPNSHPIQWNAP---QPSHISKYILRWRPKNSVGRWKEATIPGHLNSYT 667
             PV V + E     +S  + W  P     S I  Y+++ R       W   T      S+ 
Sbjct: 19790 PVNVTVKEISK--DSAYVTWEPPIIDGGSPIINYVVQKRDAERKS-WSTVTTECSKTSFR 19846

Query: 668   IKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSES 727
             +  L+ G  Y  ++ +  +YG  +               T + V    TP  P+V     
Sbjct: 19847 VANLEEGKSYFFRVFAENEYGIGDPGE------------TRDAVKASQTP-GPVVDLK-- 19891

Query: 728   VTEITASSFVVSWVS----ASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPG 783
             V  ++ SS  + W          + G+ V++ L+EE    + +   S +   +  DL  G
Sbjct: 19892 VRSVSKSSCSIGWKKPHSDGGSRIIGYVVDF-LTEENKWQRVMK--SLSLQYSAKDLTEG 19948

Query: 784   RKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWS---RPQAPITG 840
             ++Y   V   +E+GE +    T         PD  +  + D   + + +   R + PI G
Sbjct: 19949 KEYTFRVSAENENGEGTPSEITVVARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPIKG 20008

Query: 841   YRIVYSPSVE--------GSSTELNLPETANSVTLS--DLQPGV--QYNITIYAVEENQE 888
                  +PSV          + T +++  +A + TL   D Q     +Y IT+  V   +E
Sbjct: 20009 KP---APSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKE 20065

Query: 889   STPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPV 944
              T   I  +  G P   T P    ++F EVT   +T+ W PP+    S +T Y ++    
Sbjct: 20066 GT---ISIKVVGKPGIPTGP----IKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDS 20118

Query: 945   NLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKV-----FAVSHGRESKPLTAQQTTKL-D 998
                        + + TF  VT L  G+ Y F+V     + V  G +S+P+ A+    + D
Sbjct: 20119 VNNKWVTCASAVQKTTF-RVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVPD 20177

Query: 999   APTNLQFVNETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGP-SVSKYPL 1053
             AP     V+    +V + WT P+    + ITGY L          ++ N  P  +  + +
Sbjct: 20178 APPPPNIVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTPIRMRDFKV 20237

Query: 1054  RNLQPASEYTVSLVAIK----GNQESPKATGVFTTLQPGSSIPPYNTEV---TETTIVIT 1106
               L    EY   ++AI     G    P    V   L P    PP   EV   T  ++ + 
Sbjct: 20238 TGLTEGLEYEFRVMAINLAGVGKPSLPSEPVV--ALDPID--PPGKPEVINITRNSVTLI 20293

Query: 1107  WT-PAPRIGFKLGVR-------PSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRD 1158
             WT P    G KL          PS+       V     +  V+ L  G +Y + I+    
Sbjct: 20294 WTEPKYDGGHKLTGYIVEKRDLPSKSWMKANHVNVPECAFTVTDLVEGGKYEFRIRAKNT 20353

Query: 1159  GQERDAPIVN----------KVVTPLSPPT---NLHLEANPDTGVLTV-----------S 1194
                  AP  +          +  T +  PT    L ++A  DT VL             S
Sbjct: 20354 AGAISAPSESTETIICKDEYEAPTIVLDPTIKDGLTIKAG-DTIVLNAISILGKPLPKSS 20412

Query: 1195  WERS----TTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTV 1250
             W ++       DIT  +IT+TPT+     +++     D    T    +P   +   V  V
Sbjct: 20413 WSKAGKDIRPSDIT--QITSTPTSSML--TIKYATRKDAGEYTITATNP---FGTKVEHV 20465

Query: 1251  KDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEED 1310
             K          T++    PP  +  +N+  +   +TW PP   D  + +  Y   K E  
Sbjct: 20466 KV---------TVLDVPGPPGPVEISNVSAEKATLTWTPPLE-DGGSPIKSYILEKRETS 20515

Query: 1311  VAELSISPSDNAV---VLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLD------SP 1361
                 ++   D      V T L+ G EY+  VS+V    +  P++      +D       P
Sbjct: 20516 RLLWTVVSEDIQSCRHVATKLIQGNEYIFRVSAVNHYGKGEPVQSEPVKMVDRFGPPGPP 20575

Query: 1362  TGIDFSDITANSFTVHWIAP----RATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTN 1417
                + S++T N+ TV W  P     + ITGY +    +      R  + P S     +T 
Sbjct: 20576 EKPEVSNVTKNTATVSWKRPVDDGGSEITGYHVERREKKSLRWVRAIKTPVSDLRCKVTG 20635

Query: 1418  LTPGTEYVVSIVALNGREESP-------LLIGQQSTVSDVPRDLEVVAATPTSLLISWDA 1470
             L  G+ Y   + A N     P       +L+   +     P +  V   T  S  ++W  
Sbjct: 20636 LQEGSTYEFRVSAENRAGIGPPSEASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLAWGK 20695

Query: 1471  P----AVTVRYYRITYGETGGNSPVQEFTVPGSKSTA-TISGLKPGVDYTITVYAVTGRG 1525
             P     + +  Y + + + G  + +++ T    + T   +  L+    Y   + A+   G
Sbjct: 20696 PHYDGGLEITGYVVEHQKVGDEAWIKDTTGTALRITQFVVPDLQTKEKYNFRISAINDAG 20755

Query: 1526  -DSPASSKPISINYR---TEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNG 1581
                PA    + I  R    + +  ++++ T V    +S++            VT T  N 
Sbjct: 20756 VGEPAVIPDVEIVEREMAPDFELDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNI 20815

Query: 1582  PGPTKTKTAGPDQTEMTIE---GLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRP-KG 1637
                 +      +   + I        T ++V+++  +NP+G+    V   V +   P   
Sbjct: 20816 NLKNRANIENTESFTLLIIPECNRYDTGKFVMTI--ENPAGKKSGFVNVRVLDTPGPVLN 20873

Query: 1638  LAFTDVDVDSIKIAWESP----QGQVSRY--------RVTYSSPEDGIHELFPAPDGEED 1685
             L  TD+  DS+ + W+ P      +++ Y        R +YS+     H+          
Sbjct: 20874 LRPTDITKDSVTLHWDLPLIDGGSRITNYIVEKREATRKSYSTATTKCHKC--------- 20924

Query: 1686  TAELQGLRPGSEYTVSVVALHDDMESQPLIGTQ---STAIPAPTD-LKFTQVTPTSLSAQ 1741
             T ++ GL  G EY   V+A ++    +P   T+   ++  P+P D L    +T +++S  
Sbjct: 20925 TYKVTGLSEGCEYFFRVMAENEYGIGEPTETTEPVKASEAPSPPDSLNIMDITKSTVSLA 20984

Query: 1742  WTPP----NVQLTGYRVRVTPK 1759
             W  P      ++TGY +    K
Sbjct: 20985 WPKPKHDGGSKITGYVIEAQRK 21006



 Score =  129 bits (324), Expect = 3e-29
 Identities = 296/1415 (20%), Positives = 523/1415 (36%), Gaps = 202/1415 (14%)

Query: 728   VTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTAT----SVNIPDLLPG 783
             + ++++    V W    D   G  ++  + E+ +  + +    +AT       +  L+ G
Sbjct: 18305 IVDVSSDRCTVCWDPPEDD-GGCEIQNYILEKCETKRMVWSTYSATVLTPGTTVTRLIEG 18363

Query: 784   RKYIVNVYQISEDG-----EQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ--- 835
              +YI  V   ++ G     E   +++ ++   P  P  P V +V    + V W+ P+   
Sbjct: 18364 NEYIFRVRAENKIGTGPPTESKPVIAKTKYDKPGRPDPPEVTKVSKEEMTVVWNPPEYDG 18423

Query: 836   -APITGYRIVYSPSVEGSSTELN---LPETANSVTLSDLQPGVQYNITIYAVEENQESTP 891
                ITGY +            +N   +PE    V   +L P  +Y   + A  E     P
Sbjct: 18424 GKSITGYFLEKKEKHSTRWVPVNKSAIPERRMKV--QNLLPDHEYQFRVKAENEIGIGEP 18481

Query: 892   VVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPVNL- 946
              +  +        +    P + + V+ T   +T+ W  P     + + GY V++ P    
Sbjct: 18482 SLPSRPVVAKDPIEPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAPIIGYVVEMRPKIAD 18541

Query: 947   --PGEHGQRL----PISRNTFAEVTGLSPGVTYYFKVFA---VSHGRESKPLTAQQTTKL 997
               P E  +R      + R  F  VT L     Y F+V A   V  GR ++   A +  ++
Sbjct: 18542 ASPDEGWKRCNAAAQLVRKEFT-VTSLDENQEYEFRVCAQNQVGIGRPAELKEAIKPKEI 18600

Query: 998   DAPTNLQFVNETDSTVLVRWT-----------PPRAQITGYRLTV-GLTRRGQPRQYNVG 1045
               P  +         V+VR              P  ++T  ++ +  + R+GQ    +  
Sbjct: 18601 LEPPEIDLDASMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVVRKGQVDLVDT- 18659

Query: 1046  PSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVI 1105
              +    P      + +Y+++LV   G +       V  T  P S +    ++VT+T+  +
Sbjct: 18660 MAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFVNVRVLDTPGPVSDLKV--SDVTKTSCHV 18717

Query: 1106  TWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIV----------VSGLTPGVEYVYTIQV 1155
             +W P    G   G + +      RE    + S V          V+ L PG EY + +  
Sbjct: 18718 SWAPPENDG---GSQVTHYIVEKREADRKTWSTVTPEVKKTSFHVTNLVPGNEYYFRVTA 18774

Query: 1156  LRD---GQERDAPIVNKVVTPLS---PPTNLHLEANPDTGVLTVSWE---RSTTPDITGY 1206
             + +   G   D P       PLS   PP  L +         T++W    R     I GY
Sbjct: 18775 VNEYGPGVPTDVPKPVLASDPLSEPDPPRKLEVTEMTKNSA-TLAWLPPLRDGGAKIDGY 18833

Query: 1207  RITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYT-----VKDDKESVPISD 1261
              IT+     Q  +   E       S     L  G +Y   V       V   +E+  + +
Sbjct: 18834 -ITSYREEEQPADRWTEYSVVKDLSLVVTGLKEGKKYKFRVAARNAVGVSLPREAEGVYE 18892

Query: 1262  TIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVK---NEEDV---AELS 1315
                  +PP        + P+ + +       I+   +   +   K    E++V   + L+
Sbjct: 18893 AKEQLLPPKI------LMPEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLA 18946

Query: 1316  ISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSP----TGIDFSDITA 1371
             +  +D++ +L       +     S   E    T  +  +   +D+P       D SDI A
Sbjct: 18947 VHKADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPGPPQPPFDISDIDA 19006

Query: 1372  NSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPH----SRNSITLTNLTPGTEYVVS 1427
             ++ ++ W  P     G  I ++        R D V      ++ S  +  L PG EY+  
Sbjct: 19007 DACSLSWHIPLED-GGSNITNYIVEKCDVSRGDWVTALASVTKTSCRVGKLIPGQEYIFR 19065

Query: 1428  IVALN--GREE---SPLLIGQ-QSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRIT 1481
             + A N  G  E   SP ++ Q    V   P++  V       + ++WD P          
Sbjct: 19066 VRAENRFGISEPLTSPKMVAQFPFGVPSEPKNARVTKVNKDCIFVAWDRP---------- 19115

Query: 1482  YGETGGNSPVQEFTVPGSKSTATI----------------SGLKPGVDYTITVYAVTGRG 1525
               ++ G SP+  + +   +  + +                +GL  G++Y+  +YA+   G
Sbjct: 19116 --DSDGGSPIIGYLIERKERNSLLWVKANDTLVRSTEYPCAGLVEGLEYSFRIYALNKAG 19173

Query: 1526  DSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWL----PSSSPVTGYRVTTTPKNG 1581
              SP S     +  R  +D P + +V DV  +++S+ W        S + GY V      G
Sbjct: 19174 SSPPSKPTEYVTARMPVDPPGKPEVIDVTKSTVSLIWARPKHDGGSKIIGYFVEACKLPG 19233

Query: 1582  PGPTKTKTAGPD--QTEMTIEGLQPTVEYVVSVYAQN------PSGESQP---LVQTAVT 1630
                 +  TA     Q E T  GL+   +Y     A+       PS  S P   L +    
Sbjct: 19234 DKWVRCNTAPHQIPQEEYTATGLEEKAQYQFRAIARTAVNISPPSEPSDPVTILAENVPP 19293

Query: 1631  NIDRPKGL-------AFTDVDVDSIKIAWESPQGQVS-RYRVTYSSPEDGIHELFPAPDG 1682
              ID    +       A T+V +D+    +  P   VS +   T   P +GI     A   
Sbjct: 19294 RIDLSVAMKSLLTVKAGTNVCLDA--TVFGKPMPTVSWKKDGTLLKPAEGIK---MAMQR 19348

Query: 1683  EEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPA-PTDLKFTQVTPTSLSAQ 1741
                T EL  +        ++ A +        I  +    P  P  +K  ++        
Sbjct: 19349 NLCTLELFSVNRKDSGDYTITAENSSGSKSATIKLKVLDKPGPPASVKINKMYSDRAMLS 19408

Query: 1742  WTPP----NVQLTGYRVRVTPKEKTGP-MKEINLAPDSSSVVVSGLMVATKYEVSV---- 1792
             W PP      ++T Y   V  +E + P   +++     +S  V  L+   +Y+  +    
Sbjct: 19409 WEPPLEDGGSEITNY--IVDKRETSRPNWAQVSATVPITSCSVEKLIEGHEYQFRICAEN 19466

Query: 1793  -YALKDTLTSRPAQGVVTTLENVSPPRRAR---VTDATETTITISWRTKTE----TITGF 1844
              Y + D + + PA           PP R     +++ T+  +T+SW+   +     ITG+
Sbjct: 19467 KYGVGDPVFTEPA----IAKNPYDPPGRCDPPVISNITKDHMTVSWKPPADDGGSPITGY 19522

Query: 1845  QVDAVPANGQTPIQRTIKPDV-RSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAI 1903
              ++          +   KP + R+   TGLQ GT+Y+  +  +N      P   DAS A 
Sbjct: 19523 LLEKRETQAVNWTKVNRKPIIERTLKATGLQEGTEYEFRVTAINKAGPGKP--SDASKAA 19580

Query: 1904  DA---------PSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREVVPR 1950
              A         P+  +   TT +S+ +SW  P     + I GY+++ ++  S        
Sbjct: 19581 YARDPQYPPGPPAFPKVYDTTRSSVSLSWGKPAYDGGSPIIGYLVEVKRADSDNWVRCNL 19640

Query: 1951  PRP-GVTEATITGLEPGTEYTIYVIALKNNQKSEP 1984
             P+    T   +TGL   T+Y   V A+     S+P
Sbjct: 19641 PQNLQKTRFEVTGLMEDTQYQFRVYAVNKIGYSDP 19675



 Score =  123 bits (309), Expect = 2e-27
 Identities = 282/1358 (20%), Positives = 482/1358 (35%), Gaps = 200/1358 (14%)

Query: 780   LLPGRKYIVNVYQISEDGE----QSLILSTSQTTAPDAPPD-PTVDQVDDTSIVVRWSRP 834
             L+ G +YI  V  ++  G+    QS  +       P  PP+ P V  V   +  V W RP
Sbjct: 20536 LIQGNEYIFRVSAVNHYGKGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSWKRP 20595

Query: 835   Q----APITGYRIVYSPSVEGSSTE-LNLPETANSVTLSDLQPGVQYNITIYA-----VE 884
                  + ITGY +             +  P +     ++ LQ G  Y   + A     + 
Sbjct: 20596 VDDGGSEITGYHVERREKKSLRWVRAIKTPVSDLRCKVTGLQEGSTYEFRVSAENRAGIG 20655

Query: 885   ENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPES----AVTGYRVD 940
                E++  V+ ++    P   + P   D      T    ++ W  P       +TGY V+
Sbjct: 20656 PPSEASDSVLMKDAAYPPGPPSNPHVTD-----TTKKSASLAWGKPHYDGGLEITGYVVE 20710

Query: 941   VIPVN----LPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQ--QT 994
                V     +    G  L I++     V  L     Y F++ A++     +P      + 
Sbjct: 20711 HQKVGDEAWIKDTTGTALRITQFV---VPDLQTKEKYNFRISAINDAGVGEPAVIPDVEI 20767

Query: 995   TKLDAPTNLQFVNETDSTVLVR-------WTP----PRAQITGYRLTVGLTRRGQPRQYN 1043
              + +   + +   E   T++VR       + P    P  ++T  +  + L  R       
Sbjct: 20768 VEREMAPDFELDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKNRANIENTE 20827

Query: 1044  VGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTI 1103
                ++   P  N     ++ +++    G +       V  T  P  ++ P  T++T+ ++
Sbjct: 20828 -SFTLLIIPECNRYDTGKFVMTIENPAGKKSGFVNVRVLDTPGPVLNLRP--TDITKDSV 20884

Query: 1104  VITWT-PAPRIGFKLGVRPSQGGEAPREVTSDSGS------IVVSGLTPGVEYVYTIQVL 1156
              + W  P    G ++     +  EA R+  S + +        V+GL+ G EY + +   
Sbjct: 20885 TLHWDLPLIDGGSRITNYIVEKREATRKSYSTATTKCHKCTYKVTGLSEGCEYFFRVMAE 20944

Query: 1157  RD---GQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPD---ITGYRITT 1210
              +   G+  +     K     SPP +L++  +     ++++W +        ITGY I  
Sbjct: 20945 NEYGIGEPTETTEPVKASEAPSPPDSLNI-MDITKSTVSLAWPKPKHDGGSKITGYVIEA 21003

Query: 1211  TPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTII----PA 1266
                   Q   +  V   +   C   NL+ G EY   V  V     S P     +      
Sbjct: 21004 QRKGSDQWTHITTVKGLE---CVVRNLTEGEEYTFQVMAVNSAGRSAPRESRPVIVKEQT 21060

Query: 1267  VPPPTDLR-------FTNIGPDT---MRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSI 1316
             + P  DLR           G +    + V   P P++            K  + + + + 
Sbjct: 21061 MLPELDLRGIYQKLVIAKAGDNIKVEIPVLGRPKPTVTW----------KKGDQILKQTQ 21110

Query: 1317  SPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGL-------------DSPTG 1363
               +      + +L   E V S S  Y      PL  R   G                PTG
Sbjct: 21111 RVNFETTATSTILNINECVRSDSGPY------PLTARNIVGEVGDVITIQVHDIPGPPTG 21164

Query: 1364  -IDFSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNL 1418
              I F +++++  T  W  P       I+ Y +       S    E      R +   T L
Sbjct: 21165 PIKFDEVSSDFVTFSWDPPENDGGVPISNYVVEMRQTD-STTWVELATTVIRTTYKATRL 21223

Query: 1419  TPGTEYVVSIVALN------GREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAP- 1471
             T G EY   + A N      G   + ++      V   P   +V A T  S+ ISW  P 
Sbjct: 21224 TTGLEYQFRVKAQNRYGVGPGITSACIVANYPFKVPGPPGTPQVTAVTKDSMTISWHEPL 21283

Query: 1472  ---AVTVRYYRITYGETGGN--SPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGD 1526
                   +  Y +   E  G     V +  VPG+   +  SGL  G+ Y   V A    G 
Sbjct: 21284 SDGGSPILGYHVERKERNGILWQTVSKALVPGNIFKS--SGLTDGIAYEFRVIAENMAGK 21341

Query: 1527  SPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKW----LPSSSPVTGYRVTTTPKNGP 1582
             S  S     +     ID P +    ++  +++++KW          +T Y V        
Sbjct: 21342 SKPSKPSEPMLALDPIDPPGKPVPLNITRHTVTLKWAKPEYTGGFKITSYIVEKRDLPNG 21401

Query: 1583  GPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQ--TAVTNIDRPKGLAF 1640
                K   +   + E T+ GL     Y   V A+N +G   P  +   A+T  D       
Sbjct: 21402 RWLKANFSNILENEFTVSGLTEDAAYEFRVIAKNAAGAISPPSEPSDAITCRD------- 21454

Query: 1641  TDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGL-------- 1692
              DV+   IK+  +     + +    +    D      P  +  +D  EL+G         
Sbjct: 21455 -DVEAPKIKVDVKFKDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIA 21513

Query: 1693  -------------RPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTD--LKFTQVTPTS 1737
                          R    YT++  A +    ++ +   +    P P +  L  T+VT   
Sbjct: 21514 DFSTNLVNKDSTRRDSGAYTLT--ATNPGGFAKHIFNVKVLDRPGPPEGPLAVTEVTSEK 21571

Query: 1738  LSAQWTPP----NVQLTGYRVRVTPKEKTGPMKEINLAPD--SSSVVVSGLMVATKY--- 1788
                 W PP      ++  Y   +  K +T  +   N+A +   + + V+ L+   +Y   
Sbjct: 21572 CVLSWFPPLDDGGAKIDHY---IVQKRETSRLAWTNVASEVQVTKLKVTKLLKGNEYIFR 21628

Query: 1789  --EVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISW----RTKTETIT 1842
                V+ Y + + L S P    V       PP+   VT  T+ ++ + W          I 
Sbjct: 21629 VMAVNKYGVGEPLESEPVL-AVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEII 21687

Query: 1843  GFQVDAVPANGQTPIQRTIK--PDVRSYTITGLQPGTDYKIYLYTLNDNARSSP------ 1894
              + V+     GQ  I+   K   D+R Y ++GL  G +Y+  +   N    S+P      
Sbjct: 21688 NYIVERRDKAGQRWIKCNKKTLTDLR-YKVSGLTEGHEYEFRIMAENAAGISAPSPTSPF 21746

Query: 1895  -VVIDASTAIDAPSNLRFLATTPNSLLVSWQPP----RARITGYIIKYEKPGSPPREVVP 1949
                 D       P N R L T+ +S+ ++W  P     + ITGY+++   P     ++V 
Sbjct: 21747 YKACDTVFKPGPPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQIVT 21806

Query: 1950  RPRP-GVTEATITGLEPGTEYTIYVIALKNNQKSEPLI 1986
              P     T  TITGL    EY I + A+ +    EP +
Sbjct: 21807 PPAGLKATSYTITGLTENQEYKIRIYAMNSEGLGEPAL 21844



 Score =  121 bits (303), Expect = 9e-27
 Identities = 287/1414 (20%), Positives = 508/1414 (35%), Gaps = 177/1414 (12%)

Query: 610   GPVEVFITETPSQPNSHPIQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSY 666
             GP E  +  T        + WN P     ++IS YI+  R  + +  W + +      +Y
Sbjct: 24803 GPPEGPLKVTGVTAEKCYLAWNPPLQDGGANISHYIIEKRETSRLS-WTQVSTEVQALNY 24861

Query: 667   TIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSE 726
              +  L PG  Y  +++++ +YG  E             P+ S  VT       P   ++ 
Sbjct: 24862 KVTKLLPGNEYIFRVMAVNKYGIGE-------------PLESGPVTACNPYKPPGPPSTP 24908

Query: 727   SVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEP-----QYLDLPSTATSVNIPDLL 781
              V+ IT  S VV+W    D   G  +E  + E+ D+      +      T   + +  L 
Sbjct: 24909 EVSAITKDSMVVTWARPVDD-GGTEIEGYILEKRDKEGVRWTKCNKKTLTDLRLRVTGLT 24967

Query: 782   PGRKY-----IVNVYQISEDGEQSLILSTSQTTAPDAPP-DPTVDQVDDTSIVVRWSRP- 834
              G  Y       N   + E  E S+         P  PP +P V     +S+ + WS+P 
Sbjct: 24968 EGHSYEFRVAAENAAGVGEPSEPSVFYRACDALYPPGPPSNPKVTDTSRSSVSLAWSKPI 25027

Query: 835   ---QAPITGYRIVYSPSVEGSSTELNLPE--TANSVTLSDLQPGVQYNITIYAVEENQES 889
                 AP+ GY +    +     T    P        T++ L+   +YN  I A+      
Sbjct: 25028 YDGGAPVKGYVVEVKEAAADEWTTCTPPTGLQGKQFTVTKLKENTEYNFRICAINSEGVG 25087

Query: 890   TPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVK--------VTIMWTP-PE---SAVTGY 937
              P  +        R +      D    +V  ++        VTI   P PE       G 
Sbjct: 25088 EPATLPGSVVAQERIEPPEIELDADLRKVVVLRASATLRLFVTIKGRPEPEVKWEKAEGI 25147

Query: 938   RVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKL 997
               D   + +          +      VT    G   Y      + G ++  +  +     
Sbjct: 25148 LTDRAQIEVTSS------FTMLVIDNVTRFDSG--RYNLTLENNSGSKTAFVNVRVLDSP 25199

Query: 998   DAPTNLQFVNETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSVSKYPL 1053
              AP NL        +V + W PP     A+IT Y +    T R          + + + +
Sbjct: 25200 SAPVNLTIREVKKDSVTLSWEPPLIDGGAKITNYIVEKRETTRKAYATITNNCTKTTFRI 25259

Query: 1054  RNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYN------TEVTETTIVITW 1107
              NLQ    Y   ++A   + E        TT     S PP         +VT  T  I W
Sbjct: 25260 ENLQEGCSYYFRVLA---SNEYGIGLPAETTEPVKVSEPPLPPGRVTLVDVTRNTATIKW 25316

Query: 1108  T-PAPRIGFKLG----VRPSQGGEAPREVTS-DSGSIVVSGLTPGVEYVYTIQVLR---- 1157
               P    G K+        ++G E     T   +    +SGLT G EYV+ +  +     
Sbjct: 25317 EKPESDGGSKITGYVVEMQTKGSEKWSTCTQVKTLEATISGLTAGEEYVFRVAAVNEKGR 25376

Query: 1158  -DGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGY-RITTTPTNG 1215
              D ++   P++ + +  + P   L            V        D+    R   T    
Sbjct: 25377 SDPRQLGVPVIARDIE-IKPSVELPFHT------FNVKAREQLKIDVPFKGRPQATVNWR 25429

Query: 1216  QQGNSLEEVVHADQSSC---TFDNLSPGLEYNVSVYTVKDDKES----VPISDTIIPAVP 1268
             + G +L+E    + SS    T  ++    + +V  Y +     +    VPI+  ++    
Sbjct: 25430 KDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSNSAGSITVPITIIVLDRPG 25489

Query: 1269  PPTDLRFTNIGPDTMRVTWAPPP---SIDLTNFLVRYSPVKNEEDVAE---LSISPSDNA 1322
             PP  +R   +  D++ ++W PP       ++N++V     K E        +S + +  +
Sbjct: 25490 PPGPIRIDEVSCDSITISWNPPEYDGGCQISNYIVE----KKETTSTTWHIVSQAVARTS 25545

Query: 1323  VVLTNLLPGTEYVVSVSS-----VYEQHESTPLRGRQKTGLDSPTGI-DFSDITANSFTV 1376
             + +  L  G+EY   V +          ES+ +          P G       T ++  V
Sbjct: 25546 IKIVRLTTGSEYQFRVCAENRYGKSSYSESSAVVAEYPFSPPGPPGTPKVVHATKSTMLV 25605

Query: 1377  HWIAP----RATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN 1432
              W  P     + + GY + +         + +++  +   + ++ L  G  Y   + A N
Sbjct: 25606 TWQVPVNDGGSRVIGYHLEYKERSSILWSKANKILIADTQMKVSGLDEGLMYEYRVYAEN 25665

Query: 1433  ----GREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAP----AVTVRYYRITYGE 1484
                 G+              D P   EV   T  S+ + W  P       +  Y +   E
Sbjct: 25666 IAGIGKCSKSCEPVPARDPCDPPGQPEVTNITRKSVSLKWSKPHYDGGAKITGYIVERRE 25725

Query: 1485  TGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGD-SPASSKPISINYRTEID 1543
                   ++       ++   ++ L     Y   V+A       S  S     I  + +++
Sbjct: 25726 LPDGRWLKCNYTNIQETYFEVTELTEDQRYEFRVFARNAADSVSEPSESTGPIIVKDDVE 25785

Query: 1544  KPSQMQVTDVQDNSI--SVKWLPSSSPVTG--YRVTTTPKNG---PGPTKTKTAGPD-QT 1595
              P  M     +D  +  + + L  ++ + G    V +  K+G       +T+    D  T
Sbjct: 25786 PPRVMMDVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTDNHT 25845

Query: 1596  EMTIEGL--QPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKG--LAFTDVDVDSIKIA 1651
              +T++    + T +YV+++  +N +G     V   V +   P    L    +  +   ++
Sbjct: 25846 LLTVKDCIRRDTGQYVLTL--KNVAGTRSVAVNCKVLDKPGPPAGPLEINGLTAEKCSLS 25903

Query: 1652  WESPQ----GQVSRYRVTYSSPEDGIHELFPAPDGE--EDTAELQGLRPGSEYTVSVVAL 1705
             W  PQ      +  Y V      +  H  +   +GE    + ++  L  G+EY   V  +
Sbjct: 25904 WGRPQEDGGADIDYYIV---EKRETSHLAWTICEGELQMTSCKVTKLLKGNEYIFRVTGV 25960

Query: 1706  HDDMESQPLIGTQSTAIPA---------PTDLKFTQVTPTSLSAQWTPP----NVQLTGY 1752
             +     +PL   +S AI A         PT L+ T VT  S++  W+ P      +++GY
Sbjct: 25961 NKYGVGEPL---ESVAIKALDPFTVPSPPTSLEITSVTKESMTLCWSRPESDGGSEISGY 26017

Query: 1753  RVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQ--GVVTT 1810
              +    K     ++          V  +GL    +YE  VYA      S P++   ++  
Sbjct: 26018 IIERREKNSLRWVRVNKKPVYDLRVKSTGLREGCEYEYRVYAENAAGLSLPSETSPLIRA 26077

Query: 1811  LENV---SPPRRARVTDATETTITISWRTKT----ETITGFQVD---AVPANGQTPIQRT 1860
              + V   SPP + ++ D+ +TTITI+W          ITG+ V+   +   + +T IQ  
Sbjct: 26078 EDPVFLPSPPSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEYKKSDDTDWKTSIQSL 26137

Query: 1861  IKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSP 1894
                +   YTI+GL  G +Y   + ++N    S P
Sbjct: 26138 RGTE---YTISGLTTGAEYVFRVKSVNKVGASDP 26168



 Score =  120 bits (302), Expect = 1e-26
 Identities = 326/1553 (20%), Positives = 547/1553 (35%), Gaps = 248/1553 (15%)

Query: 605   YPSSSGPVEVFITETPSQPNSHPIQWNAPQ---PSHISKYILRWRPKNSVGRWKEA-TIP 660
             Y     P+ V IT+      S  + W  P+    + I+ Y++  R K S+ RW  A T+ 
Sbjct: 13188 YDVPGPPLNVTITDVNRFGVS--LTWEPPEYDGGAEITNYVIELRDKTSI-RWDTAMTVR 13244

Query: 661   GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP 720
                 S T+       V EGQ  S +        R      S +TP        E  P  P
Sbjct: 13245 AEDLSATVTD-----VVEGQEYSFRVRAQN---RIGVGKPSAATPFVKVADPIER-PSPP 13295

Query: 721   LVATSESVTEITASSFVVSWV----SASDTVSGFRVEYELSEEGDEPQY---LDLPSTAT 773
             +  TS   T+   SS  + W          + G+ +E    EEG +      + L    T
Sbjct: 13296 VNLTSSDQTQ---SSVQLKWEPPLKDGGSPILGYIIER--CEEGKDNWIRCNMKLVPELT 13350

Query: 774   SVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQV---DDTSIVVR 830
                +  L  G KY+  V   ++ G           TA DA  +PT+D     D   ++V 
Sbjct: 13351 -YKVTGLEKGNKYLYRVSAENKAGVSDPSEILGPLTADDAFVEPTMDLSAFKDGLEVIV- 13408

Query: 831   WSRP---QAPITGYRIVYSPSVEGSSTELNLPETANSVTLSD-----LQPGVQYNITIYA 882
                P     P TGY    +    G    L   +     TLS      + P  + +  IY 
Sbjct: 13409 -PNPITILVPSTGYPRPTATWCFGDKV-LETGDRVKMKTLSAYAELVISPSERSDKGIYT 13466

Query: 883   VEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYR 938
             ++       +  + +     R     +P++L+F ++T   V + W PP+    S +TGY 
Sbjct: 13467 LKLENRVKTISGEIDVNVIARPS---APKELKFGDITKDSVHLTWEPPDDDGGSPLTGYV 13523

Query: 939   VDVIPVNLPGEHGQRLPISRNTFAE-----------VTGLSPGVTYYFKVFAVSHGRESK 987
             V            ++  +SR T+ +           V  L  G  Y FKV A +     +
Sbjct: 13524 V------------EKREVSRKTWTKVMDFVTDLEFTVPDLVQGKEYLFKVCARNKCGPGE 13571

Query: 988   PLTAQQTTKL-------DAPTNLQFVNETDSTVLVRWTPPR----AQITGYRLTVGLTRR 1036
             P    +   +       D P N+++ + T +++ + W PP+    ++I GY   V    R
Sbjct: 13572 PAYVDEPVNMSTPATVPDPPENVKWRDRTANSIFLTWDPPKNDGGSRIKGY--IVERCPR 13629

Query: 1037  GQPRQYNVGPSV--SKYPLRNLQPASEYTVSLVAIK-----------------GNQESPK 1077
             G  +    G  V  +K  +  L+    Y   + A+                    QE+P+
Sbjct: 13630 GSDKWVACGEPVAETKMEVTGLEEGKWYAYRVKALNRQGASKPSRPTEEIQAVDTQEAPE 13689

Query: 1078  ATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGF-KLGVRPSQGGEAPREVTSDSG 1136
                +F  ++  + +        E    +T  P P+I + K  +   Q      E      
Sbjct: 13690 ---IFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPKKS 13746

Query: 1137  SIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHL-EANPDTGVLTVSW 1195
             ++ +          Y I+ +       A +   V+    PP    + +   ++ +LT + 
Sbjct: 13747 TVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNVLDKPGPPAAFDITDVTNESCLLTWNP 13806

Query: 1196  ERST-TPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSV-----YT 1249
              R      IT Y +    T+ +  + L   V       T   L P  EY   V     Y 
Sbjct: 13807 PRDDGGSKITNYVVERRATDSEVWHKLSSTVKDTNFKAT--KLIPNKEYIFRVAAENMYG 13864

Query: 1250  VKDDKESVPISDTIIPAVP-PPTDLRFTNIGPDTMRVTWAPPP---SIDLTNFLVRYSPV 1305
             V +  ++ PI+       P PPT L  ++I  D + +TW  P       +T + V     
Sbjct: 13865 VGEPVQASPITAKYQFDPPGPPTRLEPSDITKDAVTLTWCEPDDDGGSPITGYWVERLDP 13924

Query: 1306  KNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGID 1365
               ++ V    +   D    +  L    +Y   V +        P +  +   +  P    
Sbjct: 13925 DTDKWVRCNKMPVKDTTYRVKGLTNKKKYRFRVLAENLAGPGKPSKSTEPILIKDPIDPP 13984

Query: 1366  F-------SDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPR-EDRVPHSRNSI 1413
             +        D+   S  ++W  P     A I  Y I           R  + VP +++  
Sbjct: 13985 WPPGKPTVKDVGKTSVRLNWTKPEHDGGAKIESYVIEMLKTGTDEWVRVAEGVPTTQH-- 14042

Query: 1414  TLTNLTPGTEYVVSIVALNGREES-------PLLIGQQSTVSDVPRDLEVVAATPTSLLI 1466
              L  L  G EY   + A+N   ES       P+L  ++      PR LEV+  T  +  +
Sbjct: 14043 LLPGLMEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLEVINITKNTADL 14102

Query: 1467  SWDAPAVTVRYYRITYGETGGNSPVQEFTVPG---------------SKSTATISGLKPG 1511
              W  P            E  G SP+  + V                   +  T++ L  G
Sbjct: 14103 KWTVP------------EKDGGSPITNYIVEKRDVRRKGWQTVDTTVKDTKCTVTPLTEG 14150

Query: 1512  VDYTITVYAVTGRGDSPASSKPISINYR---TEIDKPSQMQVTDVQDNSISVKWLPSSS- 1567
               Y   V A    G S  +    S+  +   T    P  + V DV    + +KW P  + 
Sbjct: 14151 SLYVFRVAAENAIGQSDYTEIEDSVLAKDTFTTPGPPYALAVVDVTKRHVDLKWEPPKND 14210

Query: 1568  ---PVTGYRVTTTPKNGPGPTKT-KTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQP 1623
                P+  Y +    + G    K  KTAGPD      + ++ T E    V A+N +G   P
Sbjct: 14211 GGRPIQRYVIEKKERLGTRWVKAGKTAGPDCNFRVTDVIEGT-EVQFQVRAENEAGVGHP 14269

Query: 1624  LVQTAVTNIDRPKG-------LAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHEL 1676
                T + +I+ P         L  TD     I IAW+ P+           SP  G H +
Sbjct: 14270 SEPTEILSIEDPTSPPSPPLDLHVTDAGRKHIAIAWKPPE-------KNGGSPIIGYH-V 14321

Query: 1677  FPAPDGEEDTAEL-------------QGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIP 1723
                P G E    +             +G+ P  EY + V A++    S+P   +++    
Sbjct: 14322 EMCPVGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAIGVSEPSEISENVVAK 14381

Query: 1724  APTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLM 1783
              P D K T    T          + + G ++ +    +  P+  ++   D   V  S  +
Sbjct: 14382 DP-DCKPTIDLETH-------DIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRL 14433

Query: 1784  VATKYEVSVYALKDTLTSRPAQGVVT-TLEN----------------VSPPRRARVTDAT 1826
                   +S + L+   + R   G+ T TLEN                  P +  + +D T
Sbjct: 14434 TMKNDHISAH-LEVPKSVRADAGIYTITLENKLGSATASINVKVIGLPGPCKDIKASDIT 14492

Query: 1827  ETTITISWRTKT----ETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIY 1882
             +++  ++W          I  + ++   A  +T I      +  S+T+  L P  +Y   
Sbjct: 14493 KSSCKLTWEPPEFDGGTPILHYVLERREAGRRTYIPVMSGENKLSWTVKDLIPNGEYFFR 14552

Query: 1883  LYTLND-------NARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPP----RARIT 1931
             +  +N          ++  +  D     D P ++     T  ++ ++W+PP     ++I 
Sbjct: 14553 VKAVNKVGGGEYIELKNPVIAQDPKQPPDPPVDVEVHNPTAEAMTITWKPPLYDGGSKIM 14612

Query: 1932  GYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEP 1984
             GYII+    G    +        +   T  GLE G EY   V A      SEP
Sbjct: 14613 GYIIEKIAKGEERWKRCNEHLVPILTYTAKGLEEGKEYQFRVRAENAAGISEP 14665



 Score =  118 bits (296), Expect = 6e-26
 Identities = 316/1543 (20%), Positives = 554/1543 (35%), Gaps = 238/1543 (15%)

Query: 607   SSSGPVEVFIT----ETPSQPNSHPIQWNAPQPSHISKYILRWRP---------KNSVGR 653
             +SSG    F+T    +TP  P +  ++      +      L W P         KN V  
Sbjct: 24099 NSSGSKSAFVTVKVLDTPGPPQNLAVKEVRKDSA-----FLVWEPPIIDGGAKVKNYVID 24153

Query: 654   WKEATIPGHLN--------SYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTP 705
              +E+T   + N        S+ ++ L  G +Y  ++++  ++G                P
Sbjct: 24154 KRESTRKAYANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFG-------------VGVP 24200

Query: 706   VTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVS----ASDTVSGFRVEYELSEEGD 761
             V +        P SP      ++T+++ +S  + W          V G+ VE  +  +G 
Sbjct: 24201 VETVDAVKAAEPPSP--PGKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVE--MQPKGT 24256

Query: 762   EPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQ 821
             E   +   S   +  +  L  G++Y   V   +E G+    +      A D    P++  
Sbjct: 24257 EKWSIVAESKVCNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKL 24316

Query: 822   VDDTSIVVRWS--RPQAPITGY-RIVYSPSVEGS----STELNLPETANSVTLSDLQPGV 874
               +T  +      + + P+ G  R   S   +G     +T +N+ ETA S  L  ++ G 
Sbjct: 24317 PFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLH-IKEGN 24375

Query: 875   QYNITIYAVEENQESTPV-----VIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTP 929
             + +   Y V     +        VI  E  G P          ++F EV+   V I W P
Sbjct: 24376 KDDFGKYTVTATNSAGTATENLSVIVLEKPGPPVGP-------VRFDEVSADFVVISWEP 24428

Query: 930   PESA----VTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRE 985
             P       ++ Y V+         H     ++R T  ++T L  G  Y F++FA +   +
Sbjct: 24429 PAYTGGCQISNYIVEKRDTTTTTWHMVSATVARTTI-KITKLKTGTEYQFRIFAENRYGK 24487

Query: 986   SKPLTA-----QQTTKLDAPTNLQFVNE-TDSTVLVRWTPP----RAQITGYRLTVGLTR 1035
             S PL +     Q   K   P    FV   +   +LV+W  P      +I GY L      
Sbjct: 24488 SAPLDSKAVIVQYPFKEPGPPGTPFVTSISKDQMLVQWHEPVNDGGTKIIGYHLEQKEKN 24547

Query: 1036  RGQPRQYNVGP-SVSKYPLRNLQPASEYT--VSLVAIKGNQESPKATGVFTTLQPGSSIP 1092
                  + N  P   +K+    L    EY   VS   I G  +  K +  F    P    P
Sbjct: 24548 SILWVKLNKTPIQDTKFKTTGLDEGLEYEFKVSAENIVGIGKPSKVSECFVARDPCD--P 24605

Query: 1093  PYNTE---VTETTIVITWT-PAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVE 1148
             P   E   +T   + + W  PA   G K+     +  + P       G  + +  T  +E
Sbjct: 24606 PGRPEAIVITRNNVTLKWKKPAYDGGSKITGYIVEKKDLP------DGRWMKASFTNVLE 24659

Query: 1149  YVYTIQVLRDGQERDAPIVNK-VVTPLSPPT---------------NLHLEANPDTGVLT 1192
               +T+  L + Q  +  ++ +      S P+               N  L+      ++ 
Sbjct: 24660 TEFTVSGLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARDEIDAPNASLDPKYKDVIVV 24719

Query: 1193  VSWERSTTP-DITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLS---------PGLE 1242
              + E      DI G  I     + + G  LEE     +   T    +          G +
Sbjct: 24720 HAGETFVLEADIRGKPIPDVVWS-KDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQ 24778

Query: 1243  YNVSVYTVKDDKESVPISDTIIPAVPPPTD-LRFTNIGPDTMRVTWAPPPSIDLTNFLVR 1301
             Y + +  V   K S+PI+  ++    PP   L+ T +  +   + W PP      N    
Sbjct: 24779 YILKLSNVGGTK-SIPITVKVLDRPGPPEGPLKVTGVTAEKCYLAWNPPLQDGGANISHY 24837

Query: 1302  YSPVKNEEDVAELSISPSDNAV--VLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLD 1359
                 +    ++   +S    A+   +T LLPG EY+  V +V +     PL     T  +
Sbjct: 24838 IIEKRETSRLSWTQVSTEVQALNYKVTKLLPGNEYIFRVMAVNKYGIGEPLESGPVTACN 24897

Query: 1360  ------SPTGIDFSDITANSFTVHWIAP----RATITGYRIRHHPEHFSGRPREDRVPHS 1409
                    P+  + S IT +S  V W  P       I GY +    +      + ++   +
Sbjct: 24898 PYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDKEGVRWTKCNKKTLT 24957

Query: 1410  RNSITLTNLTPGTEYVVSIVALN----GREESPLLIGQQSTV---SDVPRDLEVVAATPT 1462
                + +T LT G  Y   + A N    G    P +  +          P + +V   + +
Sbjct: 24958 DLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRACDALYPPGPPSNPKVTDTSRS 25017

Query: 1463  SLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTA-----------------TI 1505
             S+ ++W  P               G +PV+ + V   ++ A                 T+
Sbjct: 25018 SVSLAWSKPIY------------DGGAPVKGYVVEVKEAAADEWTTCTPPTGLQGKQFTV 25065

Query: 1506  SGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPS 1565
             + LK   +Y   + A+   G    ++ P S+  +  I+ P      D++     V  L +
Sbjct: 25066 TKLKENTEYNFRICAINSEGVGEPATLPGSVVAQERIEPPEIELDADLR----KVVVLRA 25121

Query: 1566  SSPVTGYRVTTTPKNGPGP----TKTKTAGPD--QTEMTIEGLQPTVEYVV-------SV 1612
             S+ +   R+  T K  P P     K +    D  Q E+T       ++ V        ++
Sbjct: 25122 SATL---RLFVTIKGRPEPEVKWEKAEGILTDRAQIEVTSSFTMLVIDNVTRFDSGRYNL 25178

Query: 1613  YAQNPSGESQPLVQTAVTNI-DRPKGLAFTDVDVDSIKIAWESP----QGQVSRYRVTYS 1667
               +N SG     V   V +    P  L   +V  DS+ ++WE P      +++ Y V   
Sbjct: 25179 TLENNSGSKTAFVNVRVLDSPSAPVNLTIREVKKDSVTLSWEPPLIDGGAKITNYIVEKR 25238

Query: 1668  SPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPT- 1726
                   +      +  + T  ++ L+ G  Y   V+A ++     P   T+   +  P  
Sbjct: 25239 ETTRKAYATI-TNNCTKTTFRIENLQEGCSYYFRVLASNEYGIGLPAETTEPVKVSEPPL 25297

Query: 1727  ---DLKFTQVTPTSLSAQWTPP----NVQLTGYRVRVTPK--EKTGPMKEINLAPDSSSV 1777
                 +    VT  + + +W  P      ++TGY V +  K  EK     ++     +   
Sbjct: 25298 PPGRVTLVDVTRNTATIKWEKPESDGGSKITGYVVEMQTKGSEKWSTCTQVK----TLEA 25353

Query: 1778  VVSGLMVATKYEVSVYALKDTLTSRPAQ-GVVTTLENVS-------PPRRARVTDATETT 1829
              +SGL    +Y   V A+ +   S P Q GV     ++        P     V    +  
Sbjct: 25354 TISGLTAGEEYVFRVAAVNEKGRSDPRQLGVPVIARDIEIKPSVELPFHTFNVKAREQLK 25413

Query: 1830  ITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQ----PGTDYKIYLYT 1885
             I + ++ + +    ++ D     GQT  + T      S T+T L        D   Y   
Sbjct: 25414 IDVPFKGRPQATVNWRKD-----GQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELC 25468

Query: 1886  LNDNARS--SPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEK 1939
             ++++A S   P+ I        P  +R    + +S+ +SW PP      +I+ YI++ ++
Sbjct: 25469 VSNSAGSITVPITIIVLDRPGPPGPIRIDEVSCDSITISWNPPEYDGGCQISNYIVEKKE 25528

Query: 1940  PGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKS 1982
               S    +V +     T   I  L  G+EY   V A     KS
Sbjct: 25529 TTSTTWHIVSQ-AVARTSIKIVRLTTGSEYQFRVCAENRYGKS 25570



 Score =  118 bits (295), Expect = 8e-26
 Identities = 287/1359 (21%), Positives = 491/1359 (36%), Gaps = 205/1359 (15%)

Query: 780   LLPGRKYI-----VNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRP 834
             ++ G +YI     VN Y I E  E   +++ +    P  P  P V ++   S+ V WSRP
Sbjct: 27030 IIKGNEYIFRVRAVNKYGIGEPLESDSVVAKNAFVTPGPPGIPEVTKITKNSMTVVWSRP 27089

Query: 835   QA----PITGYRIVYSPSVEGSSTEL---NLPETANSVTLSDLQPGVQYNI-TIYAVEEN 886
              A     I+GY +           ++    + +T   VT        QY +  + A  + 
Sbjct: 27090 IADGGSDISGYFLEKRDKKSLGWFKVLKETIRDTRQKVTGLTENSDYQYRVCAVNAAGQG 27149

Query: 887   QESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVI 942
               S P    +        D    P  ++  + T   +T+ W+ P     SAVTGY V++ 
Sbjct: 27150 PFSEP---SEFYKAADPIDPPGPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVVEI- 27205

Query: 943   PVNLPGEHGQRLPIS-----RNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTK- 996
                  GE  +   +S     R T   V+ L PGV YYF+V AV+   + +P+   +  + 
Sbjct: 27206 ---RQGEEEEWTTVSTKGEVRTTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQA 27262

Query: 997   ---LDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQP--------RQYNVG 1045
                L+AP       E D  V +R T   A+  G  + V +  +G+P         + N+G
Sbjct: 27263 KDILEAP-------EIDLDVALR-TSVIAK-AGEDVQVLIPFKGRPPPTVTWRKDEKNLG 27313

Query: 1046  PSVSKYPLRNLQPASEYTVS----------LVAIKGNQESPKATGVFTTL--QPGSSIPP 1093
              S ++Y + N   +S  T+           ++ I+     PK++ V   +   P +    
Sbjct: 27314 -SDARYSIENTDSSSLLTIPQVTRNDTGKYILTIENGVGEPKSSTVSVKVLDTPAACQKL 27372

Query: 1094  YNTEVTETTIVITWTP------APRIGFKLGVRPS---QGGEAPREVTSDSGSIV-VSGL 1143
                 V+  T+ + W P      +P I + +  R +          + +S S  ++ +S  
Sbjct: 27373 QVKHVSRGTVTLLWDPPLIDGGSPIINYVIEKRDATKRTWSVVSHKCSSTSFKLIDLSEK 27432

Query: 1144  TPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDI 1203
             TP    V     +  G+  +     K     +P  +L ++ +  T V+ +SW   T PD 
Sbjct: 27433 TPFFFRVLAENEIGIGEPCETTEPVKAAEVPAPIRDLSMKDSTKTSVI-LSW---TKPDF 27488

Query: 1204  TGYRITTTPTNGQQGNSLEEVVHADQS-SCTFD----NLSPGLEYNVSVYTVKDDKESVP 1258
              G  + T     ++G   +   HA  S +C  +         LE+ V     K   + V 
Sbjct: 27489 DGGSVITEYVVERKGKGEQTWSHAGISKTCEIEVSQLKEQSVLEFRVFAKNEKGLSDPVT 27548

Query: 1259  ISDTIIP--AVPPPTDLRFTNIGPDTMRV----------TWAPPPSIDLTNFLVRYSPVK 1306
             I    +    + P  DL        T+R+             P PSI   ++L    P+K
Sbjct: 27549 IGPITVKELIITPEVDLSDIPGAQVTVRIGHNVHLELPYKGKPKPSI---SWLKDGLPLK 27605

Query: 1307  NEEDVAELSISPSDNAVVLT----NLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPT 1362
               E V     S ++N + L+        G +Y V + +      + P+          P 
Sbjct: 27606 ESEFV---RFSKTENKITLSIKNAKKEHGGKYTVILDNAV-CRIAVPITVITLGPPSKPK 27661

Query: 1363  G-IDFSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTN 1417
             G I F +I A+S  + W  P       IT Y I    E      +      +R +  + N
Sbjct: 27662 GPIRFDEIKADSVILSWDVPEDNGGGEITCYSIEKR-ETSQTNWKMVCSSVARTTFKVPN 27720

Query: 1418  LTPGTEYVVSIVALNGREESPLLIG------QQSTVSDVPRDLEVVAATPTSLLISWDAP 1471
             L    EY   + A N    S  L+        Q  +   P    +   T   + ++WDAP
Sbjct: 27721 LVKDAEYQFRVRAENRYGVSQPLVSSIIVAKHQFRIPGPPGKPVIYNVTSDGMSLTWDAP 27780

Query: 1472  AV----TVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDS 1527
                    V  + +   E       +  T P S      +GL  G+DY   VYA    G S
Sbjct: 27781 VYDGGSEVTGFHVEKKERNSILWQKVNTSPISGREYRATGLVEGLDYQFRVYAENSAGLS 27840

Query: 1528  PASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLP----SSSPVTGYRVTTTPKNGPG 1583
               S         + +D P      DV   +I++KW P      S + GY +     N   
Sbjct: 27841 SPSDPSKFTLAVSPVDPPGTPDYIDVTRETITLKWNPPLRDGGSKIVGYSIEKRQGNERW 27900

Query: 1584  PTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQN------PSGESQPLVQTAVTNIDRPKG 1637
               +       + + T+ GL P   Y   + A+N      P  +S  ++ T   N+  P  
Sbjct: 27901 -VRCNFTDVSECQYTVTGLSPGDRYEFRIIARNAVGTISPPSQSSGIIMTRDENV--PPI 27957

Query: 1638  LAFTDVDVDSI--------------------KIAWESPQGQVSRYRVTYSSPEDGIHELF 1677
             + F     D +                    ++ W     ++ +      +   G   LF
Sbjct: 27958 VEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLF 28017

Query: 1678  PAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTS 1737
                   + T + +G+     YTV         +++  +  Q T       ++FT +T   
Sbjct: 28018 V----RDATRDHRGV-----YTVEAKNASGSAKAEIKVKVQDTPGKVVGPIRFTNITGEK 28068

Query: 1738  LSAQWTPP-NVQLTGYRVRVTPKEKTGPM--KEINLAPDSSSVVVSGLMVATKYEVSVYA 1794
             ++  W  P N         +  K +T  +    I    ++ S     L+   +Y+  V A
Sbjct: 28069 MTLWWDAPLNDGCAPITHYIIEKRETSRLAWALIEDKCEAQSYTAIKLINGNEYQFRVSA 28128

Query: 1795  LKDTLTSRP--AQGVVTTLENVSP--PRRARVTDATETTITISWRTKTETITGFQVDA-- 1848
             +      RP  +  VV  ++   P  P     ++ T  +IT++W  + E+  G ++    
Sbjct: 28129 VNKFGVGRPLDSDPVVAQIQYTVPDAPGIPEPSNITGNSITLTW-ARPESDGGSEIQQYI 28187

Query: 1849  -----------VPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVI 1897
                        V    + PI  T       + +TGL  G +Y+ ++  + +NA       
Sbjct: 28188 LERREKKSTRWVKVISKRPISET------RFKVTGLTEGNEYEFHV--MAENAAGVGPAS 28239

Query: 1898  DASTAIDA---------PSNLRFLATTPNSLLVSWQPP----RARITGYIIKYEKPGSPP 1944
               S  I           P+ ++   T+  ++ + W  P       I GYII+  K     
Sbjct: 28240 GISRLIKCREPVNPPGPPTVVKVTDTSKTTVSLEWSKPVFDGGMEIIGYIIEMCKADLGD 28299

Query: 1945  REVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSE 1983
                V       T  T+T L+ G EY   V A+    K +
Sbjct: 28300 WHKVNAEACVKTRYTVTDLQAGEEYKFRVSAINGAGKGD 28338



 Score =  117 bits (294), Expect = 1e-25
 Identities = 275/1247 (22%), Positives = 460/1247 (36%), Gaps = 215/1247 (17%)

Query: 908   PSP-RDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTG 966
             P P R+L+ V+V+  + T+ W PPE    G  +     N   E  +   +  +T++  T 
Sbjct: 18297 PGPVRNLKIVDVSSDRCTVCWDPPEDD-GGCEIQ----NYILEKCETKRMVWSTYS-ATV 18350

Query: 967   LSPGVT---------YYFKVFA-----VSHGRESKPLTAQQTTKLDA-----PTNLQFVN 1007
             L+PG T         Y F+V A          ESKP+ A+  TK D      P  +  V+
Sbjct: 18351 LTPGTTVTRLIEGNEYIFRVRAENKIGTGPPTESKPVIAK--TKYDKPGRPDPPEVTKVS 18408

Query: 1008  ETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSV---SKYPLRNLQPAS 1060
             + + TV+  W PP       ITGY L      +   R   V  S     +  ++NL P  
Sbjct: 18409 KEEMTVV--WNPPEYDGGKSITGYFLE--KKEKHSTRWVPVNKSAIPERRMKVQNLLPDH 18464

Query: 1061  EYTVSLVAIK----GNQESPKATGVF-TTLQPGSSIPPYNTEVTETT---IVITWTP--- 1109
             EY   + A      G    P    V    ++P    PP N  V +TT   I + W     
Sbjct: 18465 EYQFRVKAENEIGIGEPSLPSRPVVAKDPIEPPG--PPTNFRVVDTTKHSITLGWGKPVY 18522

Query: 1110  ---APRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPI 1166
                AP IG+ + +RP     +P     D G    +     V   +T+  L + QE +  +
Sbjct: 18523 DGGAPIIGYVVEMRPKIADASP-----DEGWKRCNAAAQLVRKEFTVTSLDENQEYEFRV 18577

Query: 1167  VNKVVTPLSPPTNLHLEANP-----------DTGVLTVSWERSTTPD--ITGYRITTTPT 1213
               +    +  P  L     P           D  +  +   R+  P       R    P 
Sbjct: 18578 CAQNQVGIGRPAELKEAIKPKEILEPPEIDLDASMRKLVIVRAGCPIRLFAIVRGRPAPK 18637

Query: 1214  NGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDD-------------KESVPIS 1260
                +   ++ VV   Q      +L   + + V   + +DD             +++V ++
Sbjct: 18638 VTWRKVGIDNVVRKGQV-----DLVDTMAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFVN 18692

Query: 1261  DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELS-ISP- 1318
               ++    P +DL+ +++   +  V+WAPP + D  + +  Y   K E D    S ++P 
Sbjct: 18693 VRVLDTPGPVSDLKVSDVTKTSCHVSWAPPEN-DGGSQVTHYIVEKREADRKTWSTVTPE 18751

Query: 1319  -SDNAVVLTNLLPGTEYVVSVSSVYEQHESTP-------LRGRQKTGLDSPTGIDFSDIT 1370
                 +  +TNL+PG EY   V++V E     P       L     +  D P  ++ +++T
Sbjct: 18752 VKKTSFHVTNLVPGNEYYFRVTAVNEYGPGVPTDVPKPVLASDPLSEPDPPRKLEVTEMT 18811

Query: 1371  ANSFTVHWIAP----RATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVV 1426
              NS T+ W+ P     A I GY   +  E        +       S+ +T L  G +Y  
Sbjct: 18812 KNSATLAWLPPLRDGGAKIDGYITSYREEEQPADRWTEYSVVKDLSLVVTGLKEGKKYKF 18871

Query: 1427  SIVALNGREESPLLIGQQSTVSDVPRDLEVV-----AATPTSLLISWDAPAVTVRYYRIT 1481
              + A N    S            +PR+ E V        P  +L+         +  RI 
Sbjct: 18872 RVAARNAVGVS------------LPREAEGVYEAKEQLLPPKILMPEQITIKAGKKLRIE 18919

Query: 1482  YGETGGNSPV------QEFTVPGS------KSTATISGLKPGVDYTITVYAVTGRGDSPA 1529
                 G   P       ++  V  S        +++I  +K         Y++T    S  
Sbjct: 18920 AHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGYYSLTAENSSGT 18979

Query: 1530  SSKPISINYRTEIDKPSQMQ----VTDVQDNSISVKW-LP---SSSPVTGYRVTTTPKNG 1581
              ++ I +     +D P   Q    ++D+  ++ S+ W +P     S +T Y V     + 
Sbjct: 18980 DTQKIKV---VVMDAPGPPQPPFDISDIDADACSLSWHIPLEDGGSNITNYIVEKCDVS- 19035

Query: 1582  PGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTN------IDRP 1635
              G   T  A   +T   +  L P  EY+  V A+N  G S+PL    +           P
Sbjct: 19036 RGDWVTALASVTKTSCRVGKLIPGQEYIFRVRAENRFGISEPLTSPKMVAQFPFGVPSEP 19095

Query: 1636  KGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELF--PAPDGEEDTAE--LQG 1691
             K    T V+ D I +AW+ P        + Y       + L    A D    + E    G
Sbjct: 19096 KNARVTKVNKDCIFVAWDRPDSDGGSPIIGYLIERKERNSLLWVKANDTLVRSTEYPCAG 19155

Query: 1692  LRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTD----LKFTQVTPTSLSAQWTPP-- 1745
             L  G EY+  + AL+    S P   T+      P D     +   VT +++S  W  P  
Sbjct: 19156 LVEGLEYSFRIYALNKAGSSPPSKPTEYVTARMPVDPPGKPEVIDVTKSTVSLIWARPKH 19215

Query: 1746  --NVQLTGYRVRVTPKEKTGPMKEINLAP---DSSSVVVSGLMVATKYE---VSVYALKD 1797
                 ++ GY V    K         N AP          +GL    +Y+   ++  A+  
Sbjct: 19216 DGGSKIIGYFVEAC-KLPGDKWVRCNTAPHQIPQEEYTATGLEEKAQYQFRAIARTAVNI 19274

Query: 1798  TLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKT---ETITGFQVDAV----- 1849
             +  S P+  V    ENV P  R  ++ A ++ +T+   T      T+ G  +  V     
Sbjct: 19275 SPPSEPSDPVTILAENVPP--RIDLSVAMKSLLTVKAGTNVCLDATVFGKPMPTVSWKKD 19332

Query: 1850  -----PANG-QTPIQRTI---------KPDVRSYTITGLQPGTDYKIYLYTLNDNARSSP 1894
                  PA G +  +QR +         + D   YTIT               +  ++S+ 
Sbjct: 19333 GTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTITAEN------------SSGSKSAT 19380

Query: 1895  VVIDASTAIDAPSNLRFLATTPNSLLVSWQPP----RARITGYIIKYEKPGSPPREVVPR 1950
             + +        P++++      +  ++SW+PP     + IT YI+   +   P    V  
Sbjct: 19381 IKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYIVDKRETSRPNWAQVSA 19440

Query: 1951  PRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQKTPF 1997
               P +T  ++  L  G EY   + A       +P+   +  + K P+
Sbjct: 19441 TVP-ITSCSVEKLIEGHEYQFRICAENKYGVGDPVF-TEPAIAKNPY 19485



 Score =  117 bits (293), Expect = 1e-25
 Identities = 324/1541 (21%), Positives = 541/1541 (35%), Gaps = 222/1541 (14%)

Query: 612   VEVFITETPSQPNSHPIQ----------WNAPQP---SHISKYILRWRPKNSVGRWKEAT 658
             VEV + + P  P +  I           WN P+    S I+ Y++  R  +S   W + +
Sbjct: 13776 VEVNVLDKPGPPAAFDITDVTNESCLLTWNPPRDDGGSKITNYVVERRATDSEV-WHKLS 13834

Query: 659   IPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPF 718
                   ++    L P   Y  ++ +   YG  E             PV ++ +T +    
Sbjct: 13835 STVKDTNFKATKLIPNKEYIFRVAAENMYGVGE-------------PVQASPITAKYQFD 13881

Query: 719   SPLVATSESVTEITASSFVVSWVSASDT----VSGFRVEYELSEEGDEPQYLDLPSTATS 774
              P   T    ++IT  +  ++W    D     ++G+ VE    +     +   +P   T+
Sbjct: 13882 PPGPPTRLEPSDITKDAVTLTWCEPDDDGGSPITGYWVERLDPDTDKWVRCNKMPVKDTT 13941

Query: 775   VNIPDLLPGRKYIVNVY--QISEDGEQSL----ILSTSQTTAPDAPPDPTVDQVDDTSIV 828
               +  L   +KY   V    ++  G+ S     IL       P  P  PTV  V  TS+ 
Sbjct: 13942 YRVKGLTNKKKYRFRVLAENLAGPGKPSKSTEPILIKDPIDPPWPPGKPTVKDVGKTSVR 14001

Query: 829   VRWSRPQ----APITGY--RIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYA 882
             + W++P+    A I  Y   ++ + + E       +P T +   L  L  G +Y+  + A
Sbjct: 14002 LNWTKPEHDGGAKIESYVIEMLKTGTDEWVRVAEGVPTTQH--LLPGLMEGQEYSFRVRA 14059

Query: 883   VEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYR 938
             V +  ES P           +      PR L+ + +T     + WT PE    S +T Y 
Sbjct: 14060 VNKAGESEPSEPSDPVLCREKLYPPSPPRWLEVINITKNTADLKWTVPEKDGGSPITNYI 14119

Query: 939   VDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSH-GR------ESKPLTA 991
             V+   V   G       + ++T   VT L+ G  Y F+V A +  G+      E   L  
Sbjct: 14120 VEKRDVRRKGWQTVDTTV-KDTKCTVTPLTEGSLYVFRVAAENAIGQSDYTEIEDSVLAK 14178

Query: 992   QQTTKLDAPTNLQFVNETDSTVLVRWTPPR--AQITGYRLTVGLTRRGQPRQYNVGPSVS 1049
                T    P  L  V+ T   V ++W PP+        R  +    R   R    G +  
Sbjct: 14179 DTFTTPGPPYALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKERLGTRWVKAGKTAG 14238

Query: 1050  KYPLRNLQPASEYTVSLVAIKGNQES-----PKATGVFTTLQPGS-SIPPYNTEVTET-- 1101
                   +    E T     ++   E+      + T + +   P S   PP +  VT+   
Sbjct: 14239 PDCNFRVTDVIEGTEVQFQVRAENEAGVGHPSEPTEILSIEDPTSPPSPPLDLHVTDAGR 14298

Query: 1102  -TIVITWTP------APRIGFKLGVRPSQGGEAPREVTS----DSGSIVVSGLTPGVEYV 1150
               I I W P      +P IG+ + + P  G E    V S    D    V  G+ P  EYV
Sbjct: 14299 KHIAIAWKPPEKNGGSPIIGYHVEMCP-VGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYV 14357

Query: 1151  YTIQVLRD-GQERDAPIVNKVVT--PLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYR 1207
               ++ +   G    + I   VV   P   PT + LE +    ++ +  E+ + P    +R
Sbjct: 14358 LRVRAVNAIGVSEPSEISENVVAKDPDCKPT-IDLETH---DIIVIEGEKLSIP--VPFR 14411

Query: 1208  ITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEY------NVSVYTV----KDDKESV 1257
                 PT     +  +EV  +D+ +   D++S  LE       +  +YT+    K    + 
Sbjct: 14412 AVPVPTVSWHKDG-KEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATA 14470

Query: 1258  PISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSIS 1317
              I+  +I    P  D++ ++I   + ++TW PP     T  L      +       + + 
Sbjct: 14471 SINVKVIGLPGPCKDIKASDITKSSCKLTWEPPEFDGGTPILHYVLERREAGRRTYIPVM 14530

Query: 1318  PSDNAVVLT--NLLPGTEYVVSVSSV-------YEQHESTPLRGRQKTGLDSPTGIDFSD 1368
               +N +  T  +L+P  EY   V +V       Y + ++  +    K   D P  ++  +
Sbjct: 14531 SGENKLSWTVKDLIPNGEYFFRVKAVNKVGGGEYIELKNPVIAQDPKQPPDPPVDVEVHN 14590

Query: 1369  ITANSFTVHWIAP----RATITGYRIRH--HPEHFSGRPREDRVPHSRNSITLTNLTPGT 1422
              TA + T+ W  P     + I GY I      E    R  E  VP    + T   L  G 
Sbjct: 14591 PTAEAMTITWKPPLYDGGSKIMGYIIEKIAKGEERWKRCNEHLVPIL--TYTAKGLEEGK 14648

Query: 1423  EYVVSIVALNGREESPLLIGQQSTVSDVPRDL-EVVAATPTSLL----ISWDAPAVTVRY 1477
             EY   + A N    S        T +  P D  +V+  T   +     I+ DA      Y
Sbjct: 14649 EYQFRVRAENAAGISEPSRATPPTKAVDPIDAPKVILRTSLEVKRGDEIALDASISGSPY 14708

Query: 1478  YRITY------------------------GETGGNSP-----VQEFTVPGSKSTATISGL 1508
               IT+                        GE     P      Q  ++  SK   +   +
Sbjct: 14709 PTITWIKDENVIVPEEIKKRAAPLVRRRKGEVQEEEPFVLPLTQRLSIDNSKKGESQLRV 14768

Query: 1509  KPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLP---- 1564
             +  +     +Y +    D   +  P +++       P      D++  S+  KW P    
Sbjct: 14769 RDSLRPDHGLYMIKVENDHGIAKAPCTVSVLDTPGPPINFVFEDIRKTSVLCKWEPPLDD 14828

Query: 1565  SSSPVTGYRVTTTPKNGP-GPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQP 1623
               S +  Y +    K  P       T+     + ++  L    EY+  V A+N  G   P
Sbjct: 14829 GGSEIINYTLEKKDKTKPDSEWIVVTSTLRHCKYSVTKLIEGKEYLFRVRAENRFGPGPP 14888

Query: 1624  LVQTAVT------NIDRPKGLAFTDVDVDSIKIAWESPQ-------GQVSRYRVTYSSPE 1670
              V   +         D P      DV  +S+ + W  P+       G     R   S+  
Sbjct: 14889 CVSKPLVAKDPFGPPDAPDKPIVEDVTSNSMLVKWNEPKDNGSPILGYWLEKREVNSTHW 14948

Query: 1671  DGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHD------DMESQPLIGTQSTAIPA 1724
               +++           A + GL  G  Y   V A +          S P       + P 
Sbjct: 14949 SRVNKSLL----NALKANVDGLLEGLTYVFRVCAENAAGPGKFSPPSDPKTAHDPISPPG 15004

Query: 1725  PTDLKFTQVTPTSLSAQWTPP----NVQLTGYRVRVTPKEKTGPMKEINLAPDSSSV--- 1777
             P   + T  + T++  +W PP      ++ GY V    K+  G  +          V   
Sbjct: 15005 PPIPRVTDTSSTTIELEWEPPAFNGGGEIVGYFV---DKQLVGTNEWSRCTEKMIKVRQY 15061

Query: 1778  VVSGLMVATKYEVSVYALKDTLTSRPAQ-GVVTTLENVSPPRRARVTDATETTITISWRT 1836
              V  +     Y++ V A+       P +   VT  E   PP       A E  +++    
Sbjct: 15062 TVKEIREGADYKLRVSAVNAAGEGPPGETQPVTVAEPQEPP-------AVELDVSVKGGI 15114

Query: 1837  KTETITGFQVDAVPANGQTPIQRTIKPD--------------VRSYTITGLQPGTDYKIY 1882
             +       ++ AV      P +   K +               +S  I       D+  Y
Sbjct: 15115 QIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKDRVVIDNVGTKSELIIKDALRKDHGRY 15174

Query: 1883  LYTLNDNARSSPVVIDASTAIDAPS---NLRFLATTPNSLLVSWQPPR----ARITGYII 1935
             + T   N+  S          D P    +L+ + T     L++W  P     + ITG+II
Sbjct: 15175 VITAT-NSCGSKFAAARVEVFDVPGPVLDLKPVVTNRKMCLLNWSDPEDDGGSEITGFII 15233

Query: 1936  KYEKPGSPP-REVVPRPRPGVTEATITGLEPGTEYTIYVIA 1975
             + +       R+ +   R   ++  ITGL  G EY   VIA
Sbjct: 15234 ERKDAKMHTWRQPIETER---SKCDITGLLEGQEYKFRVIA 15271



 Score =  117 bits (293), Expect = 1e-25
 Identities = 292/1326 (22%), Positives = 488/1326 (36%), Gaps = 202/1326 (15%)

Query: 811   PDAPPDPT-VDQVDDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSV 865
             P  P  P   + V    + + W  P+    + IT Y I    +   +   ++      + 
Sbjct: 16217 PGPPVGPIKFESVSADQMTLSWFPPKDDGGSKITNYVIEKREANRKTWVHVSSEPKECTY 16276

Query: 866   TLSDLQPGVQYNITIYAVEENQESTPVVIQQETT-------GTPRSDTVPSPRDLQFVEV 918
             T+  L  G +Y   I A  +     P+  + ET        G P   TV S        V
Sbjct: 16277 TIPKLLEGHEYVFRIMAQNKYGIGEPLDSEPETARNLFSVPGAPDKPTVSS--------V 16328

Query: 919   TDVKVTIMWTPPE----SAVTGYRVDVIPVNLPG-EHGQRLPISRNTFA---EVTGLSPG 970
             T   +T+ W  PE    S VTGY +++        +   R PI   T     +VTGL  G
Sbjct: 16329 TRNSMTVNWEEPEYDGGSPVTGYWLEMKDTTSKRWKRVNRDPIKAMTLGVSYKVTGLIEG 16388

Query: 971   VTYYFKVFAVSHGR------ESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPR--- 1021
               Y F+V+A++          S P TA+       P   +  + T S+  + W+PP    
Sbjct: 16389 SDYQFRVYAINAAGVGPASLPSDPATARDPIAPPGPPFPKVTDWTKSSADLEWSPPLKDG 16448

Query: 1022  -AQITGYRLTVGLTRRGQPRQYNVGPSV----SKYPLRNLQPASEYT--VSLVAIKGNQE 1074
              +++TGY   V     G+  ++  G       +K  +  L+  + Y   V  V I G  E
Sbjct: 16449 GSKVTGY--IVEYKEEGK-EEWEKGKDKEVRGTKLVVTGLKEGAFYKFRVRAVNIAGIGE 16505

Query: 1075  SPKATGVFTT--------LQPGSSIPP----YNTEVTETTIVITWTPAPRIGFKLGVRPS 1122
               + T V           LQ  +S+      +   V      ++  P P + + +  R +
Sbjct: 16506 PGEVTDVIEMKDRLVSPDLQLDASVRDRIVVHAGGVIRIIAYVSGKPPPTVTWNMNER-T 16564

Query: 1123  QGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVT---PLSPPTN 1179
                EA  E T+ S S+V+       + VY++    +  ER   I+  V+    P+  P  
Sbjct: 16565 LPQEATIETTAISSSMVIKNCQRSHQGVYSLLAKNEAGERKKTIIVDVLDVPGPVGTPFL 16624

Query: 1180  LHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSP 1239
              H   N    +   S E      IT Y I    ++ +    +   V   + + T   L  
Sbjct: 16625 AHNLTNESCKLTWFSPEDDGGSPITNYVIEKRESDRRAWTPVTYTV--TRQNATVQGLIQ 16682

Query: 1240  GLEY--------NVSVYTVKDDKESVPISDTIIPAVPP-PTDLRFTNIGPDTMRVTWAPP 1290
             G  Y        ++ +    +  E++ I + I   VP  P DL    +  +T+ +TW PP
Sbjct: 16683 GKAYFFRIAAENSIGMGPFVETSEALVIREPI--TVPERPEDLEVKEVTKNTVTLTWNPP 16740

Query: 1291  P---SIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHES 1347
                   ++ N+++    +  E+     + +       +  L  G  Y   VS+V    + 
Sbjct: 16741 KYDGGSEIINYVLESRLIGTEKFHKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQG 16800

Query: 1348  TPLRGRQ----KTGLDSPT-GIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPR 1402
              P    +    K  L  PT  +DF D      T+  +     +TG         +SG+P+
Sbjct: 16801 KPSFCTKPITCKDELAPPTLHLDFRD----KLTIR-VGEAFALTG--------RYSGKPK 16847

Query: 1403  ------EDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQST--------VS 1448
                   +D      +  T    TP T  +  I A         ++ + ST        V+
Sbjct: 16848 PKVSWFKDEADVLEDDRTHIKTTPATLALEKIKAKRSDSGKYCVVVENSTGSRKGFCQVN 16907

Query: 1449  DVPRDLEVVA------ATPTSLLISWDAP----AVTVRYYRITYGETGGN--SPVQEFTV 1496
              V R    V        T   ++ISW  P       +  Y I   E G +   PV   T 
Sbjct: 16908 VVDRPGPPVGPVSFDEVTKDYMVISWKPPLDDGGSKITNYIIEKKEVGKDVWMPV---TS 16964

Query: 1497  PGSKSTATISGLKPGVDYTITVYAVTGRGDS-PASSKPISINYRTEI-DKPSQMQVTDVQ 1554
               +K+T  +S L  G DY   ++A    G S P  S  +    R  + D P Q  VT+V 
Sbjct: 16965 ASAKTTCKVSKLLEGKDYIFRIHAENLYGISDPLVSDSMKAKDRFRVPDAPDQPIVTEVT 17024

Query: 1555  DNSISVKWLP---SSSPVTGY---RVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEY 1608
              +S  V W        P+T Y   +  T  K     TK        T+  +  L    +Y
Sbjct: 17025 KDSALVTWNKPHDGGKPITNYILEKRETMSKRWARVTKDPIH--PYTKFRVPDLLEGCQY 17082

Query: 1609  VVSVYAQN------PSGESQPL-VQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQ----G 1657
                V A+N      PS  S+P+  +  +     P      D   +S+ + W+ P+     
Sbjct: 17083 EFRVSAENEIGIGDPSPPSKPVFAKDPIAKPSPPVNPEAIDTTCNSVDLTWQPPRHDGGS 17142

Query: 1658  QVSRYRVTYSSPEDGI-HELFPAPDGEEDTA-ELQGLRPGSEYTVSVVALHDDMESQPLI 1715
             ++  Y V Y    D         P+   +T  ++ GLR G  Y   V+A++   ES P  
Sbjct: 17143 KILGYIVEYQKVGDEEWRRANHTPESCPETKYKVTGLRDGQTYKFRVLAVNAAGESDP-- 17200

Query: 1716  GTQSTAIPAPTDLKFTQVTP-TSLSAQWTPPNVQLTGYRVRVT------PKEKTGPMKEI 1768
                   +P P  +K     P   L A          G  +R++      P  K    KE 
Sbjct: 17201 ----AHVPEPVLVKDRLEPPELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKED 17256

Query: 1769  NLAPDSSSVVVSGLMVATKYEV--------SVYAL--KDTLTSRPAQGVVTTLENVSPPR 1818
               AP  + + V+   V +K E+         +Y+L  ++   S+     V  L+   PPR
Sbjct: 17257 RDAPTKARIDVT--PVGSKLEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDKPGPPR 17314

Query: 1819  RARVTDATETTITISWRTKTE----TITGFQVDA--VPANGQTPIQRTIKPDVRSYTITG 1872
                V++  + +  ++W+   +     IT + V+   V +   +P+  T K   +S+    
Sbjct: 17315 DLEVSEIRKDSCYLTWKEPLDDGGSVITNYVVERRDVASAQWSPLSATSKK--KSHFAKH 17372

Query: 1873  LQPGTDYKIYLYTLNDNARSSPV-------VIDASTAIDAPSNLRFLATTPNSLLVSWQP 1925
             L  G  Y   +   N   R   V        +D       P +L  +      + + W  
Sbjct: 17373 LNEGNQYLFRVAAENQYGRGPFVETPKPIKALDPLHPPGPPKDLHHVDVDKTEVSLVWNK 17432

Query: 1926  P----RARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQK 1981
             P     + ITGY+++Y++ G+  ++ +        E  +TGL+ G  Y   V       K
Sbjct: 17433 PDRDGGSPITGYLVEYQEEGT--QDWIKFKTVTNLECVVTGLQQGKTYRFRV-------K 17483

Query: 1982  SEPLIG 1987
             +E ++G
Sbjct: 17484 AENIVG 17489



 Score =  114 bits (286), Expect = 9e-25
 Identities = 268/1373 (19%), Positives = 504/1373 (36%), Gaps = 176/1373 (12%)

Query: 766   LDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDT 825
             +D  +  TS  I +   G K    +   ++ G+    ++      P    +  V +  D 
Sbjct: 13045 IDTTAEQTSFRILEAKKGDKGRYKIVLQNKHGKAEGFINLKVIDVPGPVRNLEVTETFDG 13104

Query: 826   SIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETAN-SVTLSDLQPG-VQYNIT 879
              + + W  P     + I GY +V    ++  +  L      +   T++ LQ G V+Y   
Sbjct: 13105 EVSLAWEEPLTDGGSKIIGY-VVERRDIKRKTWVLATDRAESCEFTVTGLQKGGVEYLFR 13163

Query: 880   IYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVT 935
             + A        PV          + D    P ++   +V    V++ W PPE    + +T
Sbjct: 13164 VSARNRVGTGEPVETDNPVEARSKYDVPGPPLNVTITDVNRFGVSLTWEPPEYDGGAEIT 13223

Query: 936   GYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTT 995
              Y +++               + +  A VT +  G  Y F+V A +     KP  A    
Sbjct: 13224 NYVIELRDKTSIRWDTAMTVRAEDLSATVTDVVEGQEYSFRVRAQNRIGVGKPSAATPFV 13283

Query: 996   KL-------DAPTNLQFVNETDSTVLVRWTPP----RAQITGYRLTVGLTRRGQPR---- 1040
             K+         P NL   ++T S+V ++W PP     + I GY   +     G+      
Sbjct: 13284 KVADPIERPSPPVNLTSSDQTQSSVQLKWEPPLKDGGSPILGY--IIERCEEGKDNWIRC 13341

Query: 1041  QYNVGPSVSKYPLRNLQPASE--YTVSLVAIKGNQESPKATGVFTT----LQPGSSIPPY 1094
                + P ++ Y +  L+  ++  Y VS     G  +  +  G  T     ++P   +  +
Sbjct: 13342 NMKLVPELT-YKVTGLEKGNKYLYRVSAENKAGVSDPSEILGPLTADDAFVEPTMDLSAF 13400

Query: 1095  NTEV-----TETTIVI--TWTPAPRIGFKLGVRPSQGGEAPREVT-SDSGSIVVSGLTPG 1146
                +        TI++  T  P P   +  G +  + G+  +  T S    +V+S     
Sbjct: 13401 KDGLEVIVPNPITILVPSTGYPRPTATWCFGDKVLETGDRVKMKTLSAYAELVISPSERS 13460

Query: 1147  VEYVYTIQVLRDGQERDAPI-VNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPD--- 1202
              + +YT+++    +     I VN +  P +P      +   D+  LT  WE    PD   
Sbjct: 13461 DKGIYTLKLENRVKTISGEIDVNVIARPSAPKELKFGDITKDSVHLT--WE---PPDDDG 13515

Query: 1203  ---ITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEY--NVSVYTVKDDKESV 1257
                +TGY +     + +    + + V       T  +L  G EY   V         E  
Sbjct: 13516 GSPLTGYVVEKREVSRKTWTKVMDFV--TDLEFTVPDLVQGKEYLFKVCARNKCGPGEPA 13573

Query: 1258  PISDTIIPAVP-----PPTDLRFTNIGPDTMRVTWAPPPS---IDLTNFLVRYSPVKNEE 1309
              + + +  + P     PP ++++ +   +++ +TW PP +     +  ++V   P  +++
Sbjct: 13574 YVDEPVNMSTPATVPDPPENVKWRDRTANSIFLTWDPPKNDGGSRIKGYIVERCPRGSDK 13633

Query: 1310  DVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDI 1369
              VA      ++  + +T L  G  Y   V ++  Q  S P R  ++        +D  + 
Sbjct: 13634 WVA-CGEPVAETKMEVTGLEEGKWYAYRVKALNRQGASKPSRPTEEI-----QAVDTQEA 13687

Query: 1370  TANSFTVHWIAPRATITGYRIRHHPEHFSGRP-------REDRVPHSRNSITLTNLTPGT 1422
                   V  +A      G +I   P   +G+P       + D +      IT+ N+    
Sbjct: 13688 PEIFLDVKLLAGLTVKAGTKI-ELPATVTGKPEPKITWTKADMILKQDKRITIENVP--K 13744

Query: 1423  EYVVSIVALNGREESPLLI------GQQSTVSDV--------PRDLEVVAATPTSLLISW 1468
             +  V+IV     +    +I      G+ + V +V        P   ++   T  S L++W
Sbjct: 13745 KSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNVLDKPGPPAAFDITDVTNESCLLTW 13804

Query: 1469  DAP----AVTVRYYRITYGETGG------NSPVQEFTVPGSKSTATISGLKPGVDYTITV 1518
             + P       +  Y +    T        +S V++     +K       L P  +Y   V
Sbjct: 13805 NPPRDDGGSKITNYVVERRATDSEVWHKLSSTVKDTNFKATK-------LIPNKEYIFRV 13857

Query: 1519  YAVTGRG-DSPASSKPISINYRTE-IDKPSQMQVTDVQDNSISVKWL----PSSSPVTGY 1572
              A    G   P  + PI+  Y+ +    P++++ +D+  +++++ W        SP+TGY
Sbjct: 13858 AAENMYGVGEPVQASPITAKYQFDPPGPPTRLEPSDITKDAVTLTWCEPDDDGGSPITGY 13917

Query: 1573  RVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQP-------LV 1625
              V     +     +        T   ++GL    +Y   V A+N +G  +P       L+
Sbjct: 13918 WVERLDPDTDKWVRCNKMPVKDTTYRVKGLTNKKKYRFRVLAENLAGPGKPSKSTEPILI 13977

Query: 1626  QTAVTNIDRPKGLAFTDVDVDSIKIAWESPQ--GQVSRYRVTYSSPEDGIHELFPAPDGE 1683
             +  +     P      DV   S+++ W  P+  G            + G  E     +G 
Sbjct: 13978 KDPIDPPWPPGKPTVKDVGKTSVRLNWTKPEHDGGAKIESYVIEMLKTGTDEWVRVAEGV 14037

Query: 1684  EDTAE-LQGLRPGSEYTVSVVALHDDMESQ------PLIGTQSTAIPAPTD-LKFTQVTP 1735
               T   L GL  G EY+  V A++   ES+      P++  +    P+P   L+   +T 
Sbjct: 14038 PTTQHLLPGLMEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLEVINITK 14097

Query: 1736  TSLSAQWTPPNVQ----LTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVS 1791
              +   +WT P       +T Y V      + G  + ++     +   V+ L      E S
Sbjct: 14098 NTADLKWTVPEKDGGSPITNYIVEKRDVRRKG-WQTVDTTVKDTKCTVTPLT-----EGS 14151

Query: 1792  VYALKDTLTSRPAQGVVTTLEN----------VSPPRRARVTDATETTITISWRTKT--- 1838
             +Y  +    +   Q   T +E+            PP    V D T+  + + W       
Sbjct: 14152 LYVFRVAAENAIGQSDYTEIEDSVLAKDTFTTPGPPYALAVVDVTKRHVDLKWEPPKNDG 14211

Query: 1839  -ETITGFQVDAVPANGQTPIQ--RTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSP- 1894
                I  + ++     G   ++  +T  PD  ++ +T +  GT+ +  +   N+     P 
Sbjct: 14212 GRPIQRYVIEKKERLGTRWVKAGKTAGPDC-NFRVTDVIEGTEVQFQVRAENEAGVGHPS 14270

Query: 1895  ------VVIDASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPP 1944
                    + D ++    P +L         + ++W+PP     + I GY ++    G+  
Sbjct: 14271 EPTEILSIEDPTSPPSPPLDLHVTDAGRKHIAIAWKPPEKNGGSPIIGYHVEMCPVGTEK 14330

Query: 1945  -REVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQKTP 1996
                V  RP   +      G+ P  EY + V A+     SEP    +  V K P
Sbjct: 14331 WMRVNSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAIGVSEPSEISENVVAKDP 14383



 Score =  107 bits (266), Expect = 2e-22
 Identities = 292/1356 (21%), Positives = 513/1356 (37%), Gaps = 189/1356 (13%)

Query: 727   SVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQ--YLDLPSTA--TSVNIPDLLP 782
             +VTE+T+   V+SW    D   G ++++ + ++ +  +  + ++ S    T + +  LL 
Sbjct: 21563 AVTEVTSEKCVLSWFPPLDD-GGAKIDHYIVQKRETSRLAWTNVASEVQVTKLKVTKLLK 21621

Query: 783   GRKYI-----VNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAP 837
             G +YI     VN Y + E  E   +L+ +    PD P +P V  +   S+VV W  P + 
Sbjct: 21622 GNEYIFRVMAVNKYGVGEPLESEPVLAVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDS- 21680

Query: 838   ITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQ-------PGVQYNITIYAVEENQEST 890
               G   + +  VE            N  TL+DL+        G +Y   I A      S 
Sbjct: 21681 -DGGSEIINYIVERRDKAGQRWIKCNKKTLTDLRYKVSGLTEGHEYEFRIMAENAAGISA 21739

Query: 891   PVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNL 946
             P                  P + + ++ +   ++I W  P     S +TGY V++    L
Sbjct: 21740 PSPTSPFYKACDTVFKPGPPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIA---L 21796

Query: 947   PGEHGQRLPIS----RNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLD---A 999
             P E   ++       + T   +TGL+    Y  +++A++     +P     T K +    
Sbjct: 21797 PEEDEWQIVTPPAGLKATSYTITGLTENQEYKIRIYAMNSEGLGEPALVPGTPKAEDRML 21856

Query: 1000  PTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPR---QYNVGPSVSKYPLRNL 1056
             P  ++   +    V +R           RL V +  R  P      + G S+ K    ++
Sbjct: 21857 PPEIELDADLRKVVTIR------ACCTLRLFVPIKGRPAPEVKWARDHGESLDK---ASI 21907

Query: 1057  QPASEYTVSLVAIKGNQESPK----------ATGVFTTLQ----PGSSIPPYNTEVTETT 1102
             +  S YT+ +V      +S K          +   F  ++    PG        EVT+T+
Sbjct: 21908 ESTSSYTLLIVGNVNRFDSGKYILTVENSSGSKSAFVNVRVLDTPGPPQDLKVKEVTKTS 21967

Query: 1103  IVITWTPAPRI--GFKLGVRPSQGGEAPREVTS------DSGSIVVSGLTPGVEYVYTIQ 1154
             + +TW P P +  G K+     +  E+ R+  S         S  V  L  G  Y +  +
Sbjct: 21968 VTLTWDP-PLLDGGSKIKNYIVEKRESTRKAYSTVATNCHKTSWKVDQLQEGCSYYF--R 22024

Query: 1155  VLRDGQ------ERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPD---ITG 1205
             VL + +         A  V     PL P     ++   ++  +++SWE+        I G
Sbjct: 22025 VLAENEYGIGLPAETAESVKASERPLPPGKITLMDVTRNS--VSLSWEKPEHDGGSRILG 22082

Query: 1206  YRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYT-----VKDDKE-SVPI 1259
             Y I    T G    +    V   +++ T   L  G EY+  V       + D ++ SVP+
Sbjct: 22083 Y-IVEMQTKGSDKWATCATVKVTEATIT--GLIQGEEYSFRVSAQNEKGISDPRQLSVPV 22139

Query: 1260  --SDTIIPAVPPPTDLRFTNIGPDTMRV----TWAPPPSIDLTNFLVRYSPVKNEEDVAE 1313
                D +IP         FT +  + ++V       P P++      V   P+K       
Sbjct: 22140 IAKDLVIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNV---PLK---QTTR 22193

Query: 1314  LSISPSDNAVVLTNLLPGTE----YVVSV-SSVYEQHESTPLRGRQKTGLDSPTG-IDFS 1367
             ++   ++N  +LT      E    YVV + +S  E  E+  +    K G   PTG +   
Sbjct: 22194 VNAESTENNSLLTIKDACREDVGHYVVKLTNSAGEAIETLNVIVLDKPG--PPTGPVKMD 22251

Query: 1368  DITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTE 1423
             ++TA+S T+ W  P+    ++I  Y +    +  +   +      +R +I    L  G E
Sbjct: 22252 EVTADSITLSWGPPKYDGGSSINNYIVEKR-DTSTTTWQIVSATVARTTIKACRLKTGCE 22310

Query: 1424  YVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPT-------SLLISWDAP----A 1472
             Y   I A N   +S  L   + TV+  P  +     TP        S+ + W+ P     
Sbjct: 22311 YQFRIAAENRYGKSTYL-NSEPTVAQYPFKVPGPPGTPVVTLSSRDSMEVQWNEPISDGG 22369

Query: 1473  VTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSK 1532
               V  Y +   E      V+    P  ++    +GL+ GV+Y   V A    G    S  
Sbjct: 22370 SRVIGYHLERKERNSILWVKLNKTPIPQTKFKTTGLEEGVEYEFRVSAENIVGIGKPSKV 22429

Query: 1533  PISINYRTEIDKPSQMQVTDVQDNSISVKW----LPSSSPVTGYRVTTTPKNGPGPTKTK 1588
                   R   D P + +   V  NS++++W        S +TGY V           K  
Sbjct: 22430 SECYVARDPCDPPGRPEAIIVTRNSVTLQWKKPTYDGGSKITGYIVEKKELPEGRWMKAS 22489

Query: 1589  TAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE-SQPLVQT-AVTNIDR--PKGLAFTDVD 1644
                   T   + GL     Y   V A+N +G  S+P   T A+T  D   P  ++     
Sbjct: 22490 FTNIIDTHFEVTGLVEDHRYEFRVIARNAAGVFSEPSESTGAITARDEVDPPRISMDPKY 22549

Query: 1645  VDSIKI-AWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVV 1703
              D+I + A ES +         Y  P   I  +     G+++ +    L   S    + +
Sbjct: 22550 KDTIVVHAGESFKVDAD----IYGKPIPTIQWI----KGDQELSNTARLEIKSTDFATSL 22601

Query: 1704  ALHDD---------MESQPLIGTQSTAI-------PAPTD--LKFTQVTPTSLSAQWTPP 1745
             ++ D          ++++ + G +S  +       P P +  +  + VT    +  W PP
Sbjct: 22602 SVKDAVRVDSGNYILKAKNVAGERSVTVNVKVLDRPGPPEGPVVISGVTAEKCTLAWKPP 22661

Query: 1746  NVQLTGYRV--RVTPKEKTGPM--KEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTS 1801
              +Q  G  +   +  + +T  +    ++    + S  V+ L+   +Y   + A+      
Sbjct: 22662 -LQDGGSDIINYIVERRETSRLVWTVVDANVQTLSCKVTKLLEGNEYTFRIMAVNKYGVG 22720

Query: 1802  RPAQGVVTTLEN--VSP--PRRARVTDATETTITISWRTKT----ETITGFQVDAVPANG 1853
              P +      +N  V P  P+   VT  T+ ++ + W          I G+ ++     G
Sbjct: 22721 EPLESEPVVAKNPFVVPDAPKAPEVTTVTKDSMIVVWERPASDGGSEILGYVLEKRDKEG 22780

Query: 1854  --QTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDA-STAID------ 1904
                T   + +  ++R   +TGL    DY+  +   N    S P    A   A D      
Sbjct: 22781 IRWTRCHKRLIGELR-LRVTGLIENHDYEFRVSAENAAGLSEPSPPSAYQKACDPIYKPG 22839

Query: 1905  APSNLRFLATTPNSLLVSWQPP----RARITGYIIK 1936
              P+N + +  T +S+ +SW  P       I GYI++
Sbjct: 22840 PPNNPKVIDITRSSVFLSWSKPIYDGGCEIQGYIVE 22875



 Score =  106 bits (265), Expect = 2e-22
 Identities = 287/1431 (20%), Positives = 492/1431 (34%), Gaps = 191/1431 (13%)

Query: 730   EITASSFVVSWVSASDT----VSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRK 785
             +IT  S  ++W    D     ++G+ VE          + +D   T     +PDL+ G++
Sbjct: 13498 DITKDSVHLTWEPPDDDGGSPLTGYVVEKREVSRKTWTKVMDFV-TDLEFTVPDLVQGKE 13556

Query: 786   YIVNVYQISE--DGEQSLILSTSQTTAPDAPPDP--TVDQVDDT--SIVVRWSRPQ---- 835
             Y+  V   ++   GE + +      + P   PDP   V   D T  SI + W  P+    
Sbjct: 13557 YLFKVCARNKCGPGEPAYVDEPVNMSTPATVPDPPENVKWRDRTANSIFLTWDPPKNDGG 13616

Query: 836   APITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQ 895
             + I GY +   P           P     + ++ L+ G  Y   + A+     S P    
Sbjct: 13617 SRIKGYIVERCPRGSDKWVACGEPVAETKMEVTGLEEGKWYAYRVKALNRQGASKPSRPT 13676

Query: 896   QETTGTPRSDTVPSPRDLQFVEVTDVKV-------TIMWTPPESAVTGYRVDVIPVNLPG 948
             +E       +      D++ +    VK          +   PE  +T  + D+I      
Sbjct: 13677 EEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKR 13736

Query: 949   EHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNE 1008
                + +P         +  S   TY  +   V  GR +  +      K   P      + 
Sbjct: 13737 ITIENVPKKSTVTIVDSKRSDTGTYIIEAVNVC-GRATAVVEVNVLDKPGPPAAFDITDV 13795

Query: 1009  TDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTV 1064
             T+ + L+ W PPR    ++IT Y +    T      + +     + +    L P  EY  
Sbjct: 13796 TNESCLLTWNPPRDDGGSKITNYVVERRATDSEVWHKLSSTVKDTNFKATKLIPNKEYIF 13855

Query: 1065  SLVA--IKGNQESPKATGVFTTLQPGSSIPPYNTE---VTETTIVITWTP------APRI 1113
              + A  + G  E  +A+ +    Q     PP   E   +T+  + +TW        +P  
Sbjct: 13856 RVAAENMYGVGEPVQASPITAKYQFDPPGPPTRLEPSDITKDAVTLTWCEPDDDGGSPIT 13915

Query: 1114  GF---KLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTI---QVLRDGQERDAPIV 1167
             G+   +L     +     +    D+ +  V GLT   +Y + +    +   G+   +   
Sbjct: 13916 GYWVERLDPDTDKWVRCNKMPVKDT-TYRVKGLTNKKKYRFRVLAENLAGPGKPSKSTEP 13974

Query: 1168  NKVVTPLSPPTNLHLEANPDTGVLTV--SWERSTTPDITGYRITTTPTNGQQGNSLEEVV 1225
               +  P+ PP         D G  +V  +W   T P+  G     +          +E V
Sbjct: 13975 ILIKDPIDPPWPPGKPTVKDVGKTSVRLNW---TKPEHDGGAKIESYVIEMLKTGTDEWV 14031

Query: 1226  HADQSSCTFDNLSPGL----EYNVSVYTVKDDKESVPI--SDTIIPAVP-----PPTDLR 1274
                +   T  +L PGL    EY+  V  V    ES P   SD ++         PP  L 
Sbjct: 14032 RVAEGVPTTQHLLPGLMEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLE 14091

Query: 1275  FTNIGPDTMRVTWAPPPS---IDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPG 1331
               NI  +T  + W  P       +TN++V    V+ +     +  +  D    +T L  G
Sbjct: 14092 VINITKNTADLKWTVPEKDGGSPITNYIVEKRDVRRK-GWQTVDTTVKDTKCTVTPLTEG 14150

Query: 1332  TEYVVSVS-------SVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPR-- 1382
             + YV  V+       S Y + E + L     T    P  +   D+T     + W  P+  
Sbjct: 14151 SLYVFRVAAENAIGQSDYTEIEDSVLAKDTFTTPGPPYALAVVDVTKRHVDLKWEPPKND 14210

Query: 1383  --ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN----GREE 1436
                 I  Y I       +   +  +      +  +T++  GTE    + A N    G   
Sbjct: 14211 GGRPIQRYVIEKKERLGTRWVKAGKTAGPDCNFRVTDVIEGTEVQFQVRAENEAGVGHPS 14270

Query: 1437  SP---LLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQE 1493
              P   L I   ++    P DL V  A    + I+W  P            E  G SP+  
Sbjct: 14271 EPTEILSIEDPTSPPSPPLDLHVTDAGRKHIAIAWKPP------------EKNGGSPIIG 14318

Query: 1494  FTVP----GSKSTATIS-------------GLKPGVDYTITVYAVTGRGDSPASSKPISI 1536
             + V     G++    ++             G+ P  +Y + V AV   G     S+P  I
Sbjct: 14319 YHVEMCPVGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAIG----VSEPSEI 14374

Query: 1537  NYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTE 1596
             +       P      D++ + I V      S    +R    P         +    D+  
Sbjct: 14375 SENVVAKDPDCKPTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLT 14434

Query: 1597  MTIEGLQPTVEYVVSVYA---------QNPSGESQPLVQTAVTNIDRP-KGLAFTDVDVD 1646
             M  + +   +E   SV A         +N  G +   +   V  +  P K +  +D+   
Sbjct: 14435 MKNDHISAHLEVPKSVRADAGIYTITLENKLGSATASINVKVIGLPGPCKDIKASDITKS 14494

Query: 1647  SIKIAWESPQ--GQVSRYRVTYSSPEDGIHELFPAPDGEEDTA-ELQGLRPGSEYTVSVV 1703
             S K+ WE P+  G            E G     P   GE   +  ++ L P  EY   V 
Sbjct: 14495 SCKLTWEPPEFDGGTPILHYVLERREAGRRTYIPVMSGENKLSWTVKDLIPNGEYFFRVK 14554

Query: 1704  ALH-----DDME-SQPLIGTQSTAIP-APTDLKFTQVTPTSLSAQWTPP----NVQLTGY 1752
             A++     + +E   P+I       P  P D++    T  +++  W PP      ++ GY
Sbjct: 14555 AVNKVGGGEYIELKNPVIAQDPKQPPDPPVDVEVHNPTAEAMTITWKPPLYDGGSKIMGY 14614

Query: 1753  RV-RVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTL 1811
              + ++   E+       +L P   +    GL    +Y+  V A      S P++    T 
Sbjct: 14615 IIEKIAKGEERWKRCNEHLVP-ILTYTAKGLEEGKEYQFRVRAENAAGISEPSRATPPT- 14672

Query: 1812  ENVSPPRRARVTDATETTI------------------TISWRTKTETITGFQVD------ 1847
             + V P    +V   T   +                  TI+W      I   ++       
Sbjct: 14673 KAVDPIDAPKVILRTSLEVKRGDEIALDASISGSPYPTITWIKDENVIVPEEIKKRAAPL 14732

Query: 1848  --------------AVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTL-NDNA-R 1891
                            +P   +  I  + K + +      L+P  D+ +Y+  + ND+   
Sbjct: 14733 VRRRKGEVQEEEPFVLPLTQRLSIDNSKKGESQLRVRDSLRP--DHGLYMIKVENDHGIA 14790

Query: 1892  SSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPP----RARITGYIIKYEKPGSPPRE- 1946
              +P  +        P N  F      S+L  W+PP     + I  Y ++ +    P  E 
Sbjct: 14791 KAPCTVSVLDTPGPPINFVFEDIRKTSVLCKWEPPLDDGGSEIINYTLEKKDKTKPDSEW 14850

Query: 1947  VVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQKTPF 1997
             +V        + ++T L  G EY ++ +  +N     P    K  V K PF
Sbjct: 14851 IVVTSTLRHCKYSVTKLIEGKEY-LFRVRAENRFGPGPPCVSKPLVAKDPF 14900



 Score =  106 bits (264), Expect = 3e-22
 Identities = 321/1571 (20%), Positives = 563/1571 (35%), Gaps = 259/1571 (16%)

Query: 590   YGRGIGEWHCQPLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQP---SHISKYILRWR 646
             YG G+     +P++       P  V + +     N+  I+W  P+    S I+ Y++  +
Sbjct: 25278 YGIGLPAETTEPVKVSEPPLPPGRVTLVDVTR--NTATIKWEKPESDGGSKITGYVVEMQ 25335

Query: 647   PKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPV 706
              K S  +W   T    L + TI GL  G  Y  ++ ++ + G  +  +          PV
Sbjct: 25336 TKGSE-KWSTCTQVKTLEA-TISGLTAGEEYVFRVAAVNEKGRSDPRQL-------GVPV 25386

Query: 707   TSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYL 766
              +  +  E  P   L   + +V         V +         +R + +  +E      +
Sbjct: 25387 IARDI--EIKPSVELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVN-V 25443

Query: 767   DLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDP---TVDQVD 823
                 T TS++I +     K  V  Y++        I         D P  P    +D+V 
Sbjct: 25444 SSSKTVTSLSIKE---ASKEDVGTYELCVSNSAGSITVPITIIVLDRPGPPGPIRIDEVS 25500

Query: 824   DTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNIT 879
               SI + W+ P+      I+ Y +    +   +   ++      S+ +  L  G +Y   
Sbjct: 25501 CDSITISWNPPEYDGGCQISNYIVEKKETTSTTWHIVSQAVARTSIKIVRLTTGSEYQFR 25560

Query: 880   I-----YAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE--- 931
             +     Y      ES+ VV +      P S   P P   + V  T   + + W  P    
Sbjct: 25561 VCAENRYGKSSYSESSAVVAEY-----PFSPPGP-PGTPKVVHATKSTMLVTWQVPVNDG 25614

Query: 932   -SAVTGYRVDVIP-VNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFA---VSHGRES 986
              S V GY ++     ++      ++ I+ +T  +V+GL  G+ Y ++V+A      G+ S
Sbjct: 25615 GSRVIGYHLEYKERSSILWSKANKILIA-DTQMKVSGLDEGLMYEYRVYAENIAGIGKCS 25673

Query: 987   K---PLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPR----AQITGY-----RLTVG-- 1032
             K   P+ A+     D P   +  N T  +V ++W+ P     A+ITGY      L  G  
Sbjct: 25674 KSCEPVPARDPC--DPPGQPEVTNITRKSVSLKWSKPHYDGGAKITGYIVERRELPDGRW 25731

Query: 1033  --------------LTRRGQPRQY-------NVGPSVSKYPLRNLQPASEYTVSLVAIKG 1071
                           +T   + ++Y       N   SVS+         SE T  ++ +K 
Sbjct: 25732 LKCNYTNIQETYFEVTELTEDQRYEFRVFARNAADSVSE--------PSESTGPII-VKD 25782

Query: 1072  NQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGF-KLGVRPSQGGEAPRE 1130
             + E P+   V   ++    I     EV +    I   P P I + K G+   +       
Sbjct: 25783 DVEPPR---VMMDVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEII 25839

Query: 1131  VTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGV 1190
              T +   + V          Y + +      R   +  KV+    PP    LE N  T  
Sbjct: 25840 STDNHTLLTVKDCIRRDTGQYVLTLKNVAGTRSVAVNCKVLDKPGPPAG-PLEINGLTAE 25898

Query: 1191  -LTVSWERSTTP---DITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEY--- 1243
               ++SW R       DI  Y +    T+       E  +    +SC    L  G EY   
Sbjct: 25899 KCSLSWGRPQEDGGADIDYYIVEKRETSHLAWTICEGELQ--MTSCKVTKLLKGNEYIFR 25956

Query: 1244  --NVSVYTVKDDKESVPISDTIIPAVP-PPTDLRFTNIGPDTMRVTWAPPPS---IDLTN 1297
                V+ Y V +  ESV I       VP PPT L  T++  ++M + W+ P S    +++ 
Sbjct: 25957 VTGVNKYGVGEPLESVAIKALDPFTVPSPPTSLEITSVTKESMTLCWSRPESDGGSEISG 26016

Query: 1298  FLVRYSPVKNEEDVAELSISP-SDNAVVLTNLLPGTEYVVSV-----SSVYEQHESTPL- 1350
             +++     KN      ++  P  D  V  T L  G EY   V     + +    E++PL 
Sbjct: 26017 YIIERRE-KNSLRWVRVNKKPVYDLRVKSTGLREGCEYEYRVYAENAAGLSLPSETSPLI 26075

Query: 1351  RGRQKTGLDS-PTGIDFSDITANSFTVHWIAP----RATITGYRIRHHPEHFSGRPREDR 1405
             R      L S P+     D    + T+ W+ P     A ITGY + +  +       +  
Sbjct: 26076 RAEDPVFLPSPPSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEY--KKSDDTDWKTS 26133

Query: 1406  VPHSRNS-ITLTNLTPGTEYVVSIVALN-----------------GREESPLLIGQQSTV 1447
             +   R +  T++ LT G EYV  + ++N                  REE PL        
Sbjct: 26134 IQSLRGTEYTISGLTTGAEYVFRVKSVNKVGASDPSDSSDPQIAKEREEEPLF----DID 26189

Query: 1448  SDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFT-VPGSKSTATI- 1505
             S++ + L V A    ++ + +    V      + + +   +   + +     S+++ TI 
Sbjct: 26190 SEMRKTLIVKAGASFTMTVPFRGRPVP----NVLWSKPDTDLRTRAYVDTTDSRTSLTIE 26245

Query: 1506  -SGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKW-L 1563
              +       YT+T+  V       A+S  + +        P+ + V DV   S  + W +
Sbjct: 26246 NANRNDSGKYTLTIQNVLS-----AASLTLVVKVLDTPGPPTNITVQDVTKESAVLSWDV 26300

Query: 1564  PSS---SPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE 1620
             P +   +PV  Y +     +        T   ++    +  LQ    Y   V  +N  G 
Sbjct: 26301 PENDGGAPVKNYHIEKREASKKAWVSV-TNNCNRLSYKVTNLQEGAIYYFRVSGENEFGV 26359

Query: 1621  SQPLVQTAVTNIDR----PKGLAFTDVDVDSIKIAWESPQGQVSRYRVTY--SSPEDGIH 1674
               P        I      P+ L  T +  DS+ + W  P+       V Y   + E G  
Sbjct: 26360 GIPAETKEGVKITEKPSPPEKLGVTSISKDSVSLTWLKPEHDGGSRIVHYVVEALEKGQK 26419

Query: 1675  ELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVT 1734
                     +     + GLR  SEY   V A     E+Q         +  P +L    + 
Sbjct: 26420 NWVKCAVAKSTHHVVSGLRENSEYFFRVFA-----ENQ-------AGLSDPREL----LL 26463

Query: 1735  PTSLSAQWTPPNVQL-----------TGYRVRVTPKEKTGPMKEINLAPD---------- 1773
             P  +  Q  PP + +            G  ++V       P+ ++ L+ D          
Sbjct: 26464 PVLIKEQLEPPEIDMKNFPSHTVYVRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRF 26523

Query: 1774  SSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGV------VTTLENVSPPR-RARVTDAT 1826
             ++ +    L +  K  V+  A +  +T+  + G       +  L+   PP     ++D T
Sbjct: 26524 NTEITAENLTINLKESVTADAGRYEITAANSSGTTKAFINIVVLDRPGPPTGPVVISDIT 26583

Query: 1827  ETTITISWR---------------TKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTIT 1871
             E ++T+ W                 K ET T     AV       + RT+        + 
Sbjct: 26584 EESVTLKWEPPKYDGGSQVTNYILLKRETST-----AVWTEVSATVARTM------MKVM 26632

Query: 1872  GLQPGTDYKIYL-----YTLNDNARSSPVVIDASTAIDAPSNLRFLA-TTPNSLLVSWQP 1925
              L  G +Y+  +     + ++D+  S+ V +        P +  ++   T  S+ V W  
Sbjct: 26633 KLTTGEEYQFRIKAENRFGISDHIDSACVTVKLPYTTPGPPSTPWVTNVTRESITVGWHE 26692

Query: 1926  P----RARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIAL----- 1976
             P     + + GY ++ +   S   +   +     T   +T +  G  Y   V A      
Sbjct: 26693 PVSNGGSAVVGYHLEMKDRNSILWQKANKLVIRTTHFKVTTISAGLIYEFRVYAENAAGV 26752

Query: 1977  -KNNQKSEPLI 1986
              K +  SEP++
Sbjct: 26753 GKPSHPSEPVL 26763



 Score =  105 bits (263), Expect = 4e-22
 Identities = 305/1451 (21%), Positives = 530/1451 (36%), Gaps = 208/1451 (14%)

Query: 688   GHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWV----SA 743
             G Q + R      S S PV    +     P  P+      VT +T+    ++W       
Sbjct: 23693 GGQYILRASNVAGSKSFPVNVKVLDRPGPPEGPV-----QVTGVTSEKCSLTWSPPLQDG 23747

Query: 744   SDTVSGFRVEYELSEEGDEPQYLDLPS--TATSVNIPDLLPGRKYI-----VNVYQISED 796
                +S + VE     E     +  + S     S+ +  LL G +Y+     VN Y + E 
Sbjct: 23748 GSDISHYVVE---KRETSRLAWTVVASEVVTNSLKVTKLLEGNEYVFRIMAVNKYGVGEP 23804

Query: 797   GEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ----APITGYRIVYSPSVEG- 851
              E + +L  +    P  P    V  +   S+ V W+RP     + I GY IV      G 
Sbjct: 23805 LESAPVLMKNPFVLPGPPKSLEVTNIAKDSMTVCWNRPDSDGGSEIIGY-IVEKRDRSGI 23863

Query: 852   ---SSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVP 908
                   +  + +    VT        ++ ++        E +P  +  +    P     P
Sbjct: 23864 RWIKCNKRRITDLRLRVTGLTEDHEYEFRVSAENAAGVGEPSPATVYYKAC-DPVFKPGP 23922

Query: 909   SPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPGEHGQRLPIS---RNTF 961
              P +   V+ T   +T+ W  P     S + GY V++   +   E  Q +      R T 
Sbjct: 23923 -PTNAHIVDTTKNSITLAWGKPIYDGGSEILGYVVEICKAD--EEEWQIVTPQTGLRVTR 23979

Query: 962   AEVTGLSPGVTYYFKVFAVSH----GRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRW 1017
              E++ L+    Y  +V A++        S P T +   KL+AP  L   +E    ++VR 
Sbjct: 23980 FEISKLTEHQEYKIRVCALNKVGLGEATSVPGTVKPEDKLEAP-ELDLDSELRKGIVVR- 24037

Query: 1018  TPPRAQITGYRLTVGLTRRGQPR----------------QYNVGPSVSKYPLRNL--QPA 1059
                     G    + +  +G+P                 Q   G + ++  + N     A
Sbjct: 24038 -------AGGSARIHIPFKGRPTPEITWSREEGEFTDKVQIEKGVNYTQLSIDNCDRNDA 24090

Query: 1060  SEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYN---TEVTETTIVITWTPAPRI--G 1114
              +Y + L    G++ +     V  T  PG   PP N    EV + +  + W P P I  G
Sbjct: 24091 GKYILKLENSSGSKSAFVTVKVLDT--PG---PPQNLAVKEVRKDSAFLVWEP-PIIDGG 24144

Query: 1115  FKLGVRPSQGGEAPREVTSD------SGSIVVSGLTPGVEYVYTIQVLRD---GQERDAP 1165
              K+        E+ R+  ++        S  V  LT G  Y + +    +   G   +  
Sbjct: 24145 AKVKNYVIDKRESTRKAYANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFGVGVPVETV 24204

Query: 1166  IVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPD---ITGYRITTTPTNGQQGNSLE 1222
                K   P SPP  + L     T   ++ WE+        + GY +   P   ++ + + 
Sbjct: 24205 DAVKAAEPPSPPGKVTLTDVSQTSA-SLMWEKPEHDGGSRVLGYVVEMQPKGTEKWSIVA 24263

Query: 1223  EVVHADQSSCTFDNLSPGLEY--NVSVYTVKDDKE----SVPI---SDTIIPAVPPPTDL 1273
             E   +   +     LS G EY   V  Y  K   +     VP+     TI P++  P + 
Sbjct: 24264 E---SKVCNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKLPFNT 24320

Query: 1274  RFTNIGPD---TMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLP 1330
                  G D    + V   P P+I   +++    P+K       +++  +  + VL ++  
Sbjct: 24321 YSIQAGEDLKIEIPVIGRPRPNI---SWVKDGEPLK---QTTRVNVEETATSTVL-HIKE 24373

Query: 1331  GTE------YVVSVSSVYEQHESTPLRGRQKTGLDSPTG-IDFSDITANSFTVHWIAPRA 1383
             G +       V + +S     E+  +   +K G   P G + F +++A+   + W  P  
Sbjct: 24374 GNKDDFGKYTVTATNSAGTATENLSVIVLEKPG--PPVGPVRFDEVSADFVVISWEPPAY 24431

Query: 1384  T----ITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPL 1439
             T    I+ Y +    +  +          +R +I +T L  GTEY   I A N   +S  
Sbjct: 24432 TGGCQISNYIVEKR-DTTTTTWHMVSATVARTTIKITKLKTGTEYQFRIFAENRYGKSAP 24490

Query: 1440  LIGQQSTVS------DVPRDLEVVAATPTSLLISWDAP----AVTVRYYRITYGETGGNS 1489
             L  +   V         P    V + +   +L+ W  P       +  Y +   E     
Sbjct: 24491 LDSKAVIVQYPFKEPGPPGTPFVTSISKDQMLVQWHEPVNDGGTKIIGYHLEQKEKNSIL 24550

Query: 1490  PVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQ 1549
              V+    P   +    +GL  G++Y   V A    G    S        R   D P + +
Sbjct: 24551 WVKLNKTPIQDTKFKTTGLDEGLEYEFKVSAENIVGIGKPSKVSECFVARDPCDPPGRPE 24610

Query: 1550  VTDVQDNSISVKW----LPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPT 1605
                +  N++++KW        S +TGY V           K       +TE T+ GL   
Sbjct: 24611 AIVITRNNVTLKWKKPAYDGGSKITGYIVEKKDLPDGRWMKASFTNVLETEFTVSGLVED 24670

Query: 1606  VEYVVSVYAQNPSGE-SQPLVQT-AVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYR 1663
               Y   V A+N +G  S+P   + A+T  D        ++D  +  +  +     V    
Sbjct: 24671 QRYEFRVIARNAAGNFSEPSDSSGAITARD--------EIDAPNASLDPKYKDVIVVHAG 24722

Query: 1664  VTYSSPED----GIHELFPAPDGE--EDTAELQGLRPGSEYTVSVV--ALHDD-----ME 1710
              T+    D     I ++  + DG+  E+TA    ++   + T  VV   +  D     ++
Sbjct: 24723 ETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQYILK 24782

Query: 1711  SQPLIGTQSTAI-------PAPTD--LKFTQVTPTSLSAQWTPPNVQLTGYRVR--VTPK 1759
                + GT+S  I       P P +  LK T VT       W PP +Q  G  +   +  K
Sbjct: 24783 LSNVGGTKSIPITVKVLDRPGPPEGPLKVTGVTAEKCYLAWNPP-LQDGGANISHYIIEK 24841

Query: 1760  EKTGPMK--EINLAPDSSSVVVSGLMVATKY-----EVSVYALKDTLTSRPAQGVVTTLE 1812
              +T  +   +++    + +  V+ L+   +Y      V+ Y + + L S P        +
Sbjct: 24842 RETSRLSWTQVSTEVQALNYKVTKLLPGNEYIFRVMAVNKYGIGEPLESGPVT-ACNPYK 24900

Query: 1813  NVSPPRRARVTDATETTITISWRTKTE----TITGFQVDAVPANG--QTPIQRTIKPDVR 1866
                PP    V+  T+ ++ ++W    +     I G+ ++     G   T   +    D+R
Sbjct: 24901 PPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDKEGVRWTKCNKKTLTDLR 24960

Query: 1867  SYTITGLQPGTDYKIYLYTLNDNARSSPV-------VIDASTAIDAPSNLRFLATTPNSL 1919
                +TGL  G  Y+  +   N      P          DA      PSN +   T+ +S+
Sbjct: 24961 -LRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRACDALYPPGPPSNPKVTDTSRSSV 25019

Query: 1920  LVSWQPP----RARITGYIIKYEKPGSPPREVVPRPRPGV--TEATITGLEPGTEYTIYV 1973
              ++W  P     A + GY+++  K  +        P  G+   + T+T L+  TEY   +
Sbjct: 25020 SLAWSKPIYDGGAPVKGYVVEV-KEAAADEWTTCTPPTGLQGKQFTVTKLKENTEYNFRI 25078

Query: 1974  IALKNNQKSEP 1984
              A+ +    EP
Sbjct: 25079 CAINSEGVGEP 25089



 Score =  103 bits (258), Expect = 2e-21
 Identities = 284/1417 (20%), Positives = 486/1417 (34%), Gaps = 169/1417 (11%)

Query: 606   PSSSGPVEVFITETPSQPNSHPIQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGH 662
             P   GPVE+    +        + W  P     S I  YIL  R  + +  W   +    
Sbjct: 20473 PGPPGPVEI----SNVSAEKATLTWTPPLEDGGSPIKSYILEKRETSRL-LWTVVSEDIQ 20527

Query: 663   LNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLV 722
                +    L  G  Y  ++ ++  YG  E             PV S  V        P  
Sbjct: 20528 SCRHVATKLIQGNEYIFRVSAVNHYGKGE-------------PVQSEPVKMVDRFGPPGP 20574

Query: 723   ATSESVTEITASSFVVSWVSASDT----VSGFRVEYELSEEGDEPQYLDLPSTATSVNIP 778
                  V+ +T ++  VSW    D     ++G+ VE    +     + +  P +     + 
Sbjct: 20575 PEKPEVSNVTKNTATVSWKRPVDDGGSEITGYHVERREKKSLRWVRAIKTPVSDLRCKVT 20634

Query: 779   DLLPGRKYIVNVYQISEDG------EQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWS 832
              L  G  Y   V   +  G          +L       P  P +P V      S  + W 
Sbjct: 20635 GLQEGSTYEFRVSAENRAGIGPPSEASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLAWG 20694

Query: 833   RPQ----APITGYRIVYSPSVEGSSTELNLPETANSVT---LSDLQPGVQYNITIYAVEE 885
             +P       ITGY +V    V   +   +   TA  +T   + DLQ   +YN  I A+ +
Sbjct: 20695 KPHYDGGLEITGY-VVEHQKVGDEAWIKDTTGTALRITQFVVPDLQTKEKYNFRISAIND 20753

Query: 886   NQESTPVVIQQ-ETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPV 944
                  P VI   E      +       +L+   V    ++I    P        V     
Sbjct: 20754 AGVGEPAVIPDVEIVEREMAPDFELDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKD 20813

Query: 945   NLPGEHGQRLPISRNTFAEVTGLSPGVTYYF--KVFAVSHGRESKPLTAQQTTKLDAP-- 1000
             N+  ++   +    NT +    + P    Y   K          K         LD P  
Sbjct: 20814 NINLKNRANI---ENTESFTLLIIPECNRYDTGKFVMTIENPAGKKSGFVNVRVLDTPGP 20870

Query: 1001  -TNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSK-----YPLR 1054
               NL+  + T  +V + W  P     G R+T  +  + +  + +   + +K     Y + 
Sbjct: 20871 VLNLRPTDITKDSVTLHWDLPLID-GGSRITNYIVEKREATRKSYSTATTKCHKCTYKVT 20929

Query: 1055  NLQPASEYTVSLVAIK--GNQESPKATGVFTTLQPGSSIPPYNT-EVTETTIVITWTPAP 1111
              L    EY   ++A    G  E  + T      +  S     N  ++T++T+ + W P P
Sbjct: 20930 GLSEGCEYFFRVMAENEYGIGEPTETTEPVKASEAPSPPDSLNIMDITKSTVSLAW-PKP 20988

Query: 1112  R-------IGFKLGVRPSQGGEAPREVTSDSG-SIVVSGLTPGVEYVYTIQVL----RDG 1159
             +        G+ +  +  +G +    +T+  G   VV  LT G EY + +  +    R  
Sbjct: 20989 KHDGGSKITGYVIEAQ-RKGSDQWTHITTVKGLECVVRNLTEGEEYTFQVMAVNSAGRSA 21047

Query: 1160  QERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWE--RSTTPDITGYRITTTPTNGQQ 1217
                  P++ K  T L     L L       V+  + +  +   P +   + T T   G Q
Sbjct: 21048 PRESRPVIVKEQTMLP---ELDLRGIYQKLVIAKAGDNIKVEIPVLGRPKPTVTWKKGDQ 21104

Query: 1218  G-NSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAV-----PPPT 1271
                  + V     ++ T  N++  +  +   Y +        + D I   V     PP  
Sbjct: 21105 ILKQTQRVNFETTATSTILNINECVRSDSGPYPLTARNIVGEVGDVITIQVHDIPGPPTG 21164

Query: 1272  DLRFTNIGPDTMRVTWAPPPS---IDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNL 1328
              ++F  +  D +  +W PP +   + ++N++V      +   V EL+ +        T L
Sbjct: 21165 PIKFDEVSSDFVTFSWDPPENDGGVPISNYVVEMRQTDSTTWV-ELATTVIRTTYKATRL 21223

Query: 1329  LPGTEYVVSVSS-----VYEQHESTPLRGRQKTGLDSPTGI-DFSDITANSFTVHWIAP- 1381
               G EY   V +     V     S  +       +  P G    + +T +S T+ W  P 
Sbjct: 21224 TTGLEYQFRVKAQNRYGVGPGITSACIVANYPFKVPGPPGTPQVTAVTKDSMTISWHEPL 21283

Query: 1382  ---RATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN------ 1432
                 + I GY +     +        +     N    + LT G  Y   ++A N      
Sbjct: 21284 SDGGSPILGYHVERKERNGILWQTVSKALVPGNIFKSSGLTDGIAYEFRVIAENMAGKSK 21343

Query: 1433  -GREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPV 1491
               +   P+L          P  L +   T T   + W  P  T  +   +Y     + P 
Sbjct: 21344 PSKPSEPMLALDPIDPPGKPVPLNITRHTVT---LKWAKPEYTGGFKITSYIVEKRDLPN 21400

Query: 1492  QEFTVPG----SKSTATISGLKPGVDYTITVYAVTGRGD-SPASSKPISINYRTEIDKPS 1546
               +         ++  T+SGL     Y   V A    G  SP S    +I  R +++ P 
Sbjct: 21401 GRWLKANFSNILENEFTVSGLTEDAAYEFRVIAKNAAGAISPPSEPSDAITCRDDVEAPK 21460

Query: 1547  QMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTK------TKTAGPDQTEMTIE 1600
                    +D  I             +R+       P PT        +  G  + E+ I 
Sbjct: 21461 IKVDVKFKDTVI-------LKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIA 21513

Query: 1601  GLQPTV---------EYVVSVYAQNPSGESQPLVQTAVTNIDRP----KGLAFTDVDVDS 1647
                  +             ++ A NP G ++ +    V  +DRP      LA T+V  + 
Sbjct: 21514 DFSTNLVNKDSTRRDSGAYTLTATNPGGFAKHIFNVKV--LDRPGPPEGPLAVTEVTSEK 21571

Query: 1648  IKIAWESP---QGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVA 1704
               ++W  P    G    + +        +     A + +    ++  L  G+EY   V+A
Sbjct: 21572 CVLSWFPPLDDGGAKIDHYIVQKRETSRLAWTNVASEVQVTKLKVTKLLKGNEYIFRVMA 21631

Query: 1705  LH-----DDMESQPLIGTQSTAIP-APTDLKFTQVTPTSLSAQWTPPN----VQLTGYRV 1754
             ++     + +ES+P++       P  P + + T +T  S+   W  P+     ++  Y V
Sbjct: 21632 VNKYGVGEPLESEPVLAVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEIINYIV 21691

Query: 1755  RVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYA-----LKDTLTSRPAQGVVT 1809
                 K     +K            VSGL    +YE  + A     +     + P      
Sbjct: 21692 ERRDKAGQRWIKCNKKTLTDLRYKVSGLTEGHEYEFRIMAENAAGISAPSPTSPFYKACD 21751

Query: 1810  TLENVSPPRRARVTDATETTITISWRTKT----ETITGFQVD-AVPANGQTPIQRTIKP- 1863
             T+    PP   RV D + ++I+I+W          ITG+ V+ A+P   +  I   + P 
Sbjct: 21752 TVFKPGPPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQI---VTPP 21808

Query: 1864  ---DVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVI 1897
                   SYTITGL    +YKI +Y +N      P ++
Sbjct: 21809 AGLKATSYTITGLTENQEYKIRIYAMNSEGLGEPALV 21845



 Score =  101 bits (252), Expect = 7e-21
 Identities = 270/1291 (20%), Positives = 463/1291 (35%), Gaps = 206/1291 (15%)

Query: 866   TLSDLQPGVQYNITIYAVEENQEST-PVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVT 924
             T++ L  G +Y   + A  EN+  T P    +      + D    P   +  +V+  ++T
Sbjct: 18356 TVTRLIEGNEYIFRVRA--ENKIGTGPPTESKPVIAKTKYDKPGRPDPPEVTKVSKEEMT 18413

Query: 925   IMWTPPE----SAVTGYRVDVIPVNLPGEHGQR-LPISRNTFAE----VTGLSPGVTYYF 975
             ++W PPE     ++TGY ++        +H  R +P++++   E    V  L P   Y F
Sbjct: 18414 VVWNPPEYDGGKSITGYFLEK-----KEKHSTRWVPVNKSAIPERRMKVQNLLPDHEYQF 18468

Query: 976   KVFAVSH------GRESKPLTAQQTTKLDAP-TNLQFVNETDSTVLVRWTPP----RAQI 1024
             +V A +          S+P+ A+   +   P TN + V+ T  ++ + W  P     A I
Sbjct: 18469 RVKAENEIGIGEPSLPSRPVVAKDPIEPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAPI 18528

Query: 1025  TGY------RLTVGLTRRGQPRQYNVGPSVSK-YPLRNLQPASEYTVSL-----VAIKGN 1072
              GY      ++       G  R       V K + + +L    EY   +     V I   
Sbjct: 18529 IGYVVEMRPKIADASPDEGWKRCNAAAQLVRKEFTVTSLDENQEYEFRVCAQNQVGIGRP 18588

Query: 1073  QESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWT-------------PAPRIGFKLGV 1119
              E  +A      L+P    P  + + +   +VI                PAP++ ++   
Sbjct: 18589 AELKEAIKPKEILEP----PEIDLDASMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVG 18644

Query: 1120  RPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTN 1179
               +   +   ++      +V+   T      Y++ ++    E+   +  +V+    P ++
Sbjct: 18645 IDNVVRKGQVDLVDTMAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFVNVRVLDTPGPVSD 18704

Query: 1180  LHLEANPDTGVLTVSW---ERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDN 1236
             L +     T    VSW   E      +T Y +     + +  +++   V   ++S    N
Sbjct: 18705 LKVSDVTKTSC-HVSWAPPENDGGSQVTHYIVEKREADRKTWSTVTPEVK--KTSFHVTN 18761

Query: 1237  LSPGLEYNVSVYTVKDDKESVP--ISDTIIPAVP-----PPTDLRFTNIGPDTMRVTWAP 1289
             L PG EY   V  V +    VP  +   ++ + P     PP  L  T +  ++  + W P
Sbjct: 18762 LVPGNEYYFRVTAVNEYGPGVPTDVPKPVLASDPLSEPDPPRKLEVTEMTKNSATLAWLP 18821

Query: 1290  P---PSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHE 1346
             P       +  ++  Y   +   D         D ++V+T L  G +Y   V++      
Sbjct: 18822 PLRDGGAKIDGYITSYREEEQPADRWTEYSVVKDLSLVVTGLKEGKKYKFRVAARNAVGV 18881

Query: 1347  STPLRGR----QKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPR 1402
             S P         K  L  P  +    IT  +             G ++R    H  G+P 
Sbjct: 18882 SLPREAEGVYEAKEQLLPPKILMPEQITIKA-------------GKKLRIEA-HVYGKPH 18927

Query: 1403  --------EDRV----------PHSRNSITLTNLTPGTEYVVSIVALNGR----EESPLL 1440
                     ED V            S + + + ++T       S+ A N      ++  ++
Sbjct: 18928 PTCKWKKGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVV 18987

Query: 1441  IGQQSTVSDVPRDLEVVAATPTSLLISWDAP----AVTVRYYRITYGETGGNSPVQEFTV 1496
             +         P D+  + A   SL  SW  P       +  Y +   +      V     
Sbjct: 18988 VMDAPGPPQPPFDISDIDADACSL--SWHIPLEDGGSNITNYIVEKCDVSRGDWVTALAS 19045

Query: 1497  PGSKSTATISGLKPGVDYTITVYAVTGRGDS-PASSKPISINYRTEI-DKPSQMQVTDVQ 1554
               +K++  +  L PG +Y   V A    G S P +S  +   +   +  +P   +VT V 
Sbjct: 19046 V-TKTSCRVGKLIPGQEYIFRVRAENRFGISEPLTSPKMVAQFPFGVPSEPKNARVTKVN 19104

Query: 1555  DNSISVKW-LPSS---SPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVV 1610
              + I V W  P S   SP+ GY +    +N     K        TE    GL   +EY  
Sbjct: 19105 KDCIFVAWDRPDSDGGSPIIGYLIERKERNSLLWVKANDTLVRSTEYPCAGLVEGLEYSF 19164

Query: 1611  SVYAQNPSGESQPLVQTAVTN----IDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTY 1666
              +YA N +G S P   T        +D P      DV   ++ + W  P+       + Y
Sbjct: 19165 RIYALNKAGSSPPSKPTEYVTARMPVDPPGKPEVIDVTKSTVSLIWARPKHDGGSKIIGY 19224

Query: 1667  -----SSPEDGIHELFPAPDG---EEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQ 1718
                    P D       AP     EE TA   GL   ++Y    +A      S P     
Sbjct: 19225 FVEACKLPGDKWVRCNTAPHQIPQEEYTAT--GLEEKAQYQFRAIARTAVNISPP----- 19277

Query: 1719  STAIPAPTDLKFTQVTPTSLSAQWTPPNVQLT-GYRVRVTPKEKTG----------PMKE 1767
                   P+D       P ++ A+  PP + L+   +  +T K  T           PM  
Sbjct: 19278 ----SEPSD-------PVTILAENVPPRIDLSVAMKSLLTVKAGTNVCLDATVFGKPMPT 19326

Query: 1768  INLAPDSSSVV-VSGLMVATKYEVSVYAL-----KD----TLTSRPAQGV------VTTL 1811
             ++   D + +    G+ +A +  +    L     KD    T+T+  + G       +  L
Sbjct: 19327 VSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTITAENSSGSKSATIKLKVL 19386

Query: 1812  ENVSPPRRARVTDATETTITISWRTKTET----ITGFQVDAVPANGQTPIQRTIKPDVRS 1867
             +   PP   ++         +SW    E     IT + VD    +     Q +    + S
Sbjct: 19387 DKPGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYIVDKRETSRPNWAQVSATVPITS 19446

Query: 1868  YTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTA---IDAPSNLR---FLATTPNSLLV 1921
              ++  L  G +Y+  +   N      PV  + + A    D P           T + + V
Sbjct: 19447 CSVEKLIEGHEYQFRICAENKYGVGDPVFTEPAIAKNPYDPPGRCDPPVISNITKDHMTV 19506

Query: 1922  SWQPPR----ARITGYIIKYEKPGSPPREVVPRPRPGVTEATI--TGLEPGTEYTIYVIA 1975
             SW+PP     + ITGY++  EK  +         R  + E T+  TGL+ GTEY   V A
Sbjct: 19507 SWKPPADDGGSPITGYLL--EKRETQAVNWTKVNRKPIIERTLKATGLQEGTEYEFRVTA 19564

Query: 1976  LKNNQKSEPLIGRKKTVQKTPFVTHPGYDTG 2006
             +    K+ P  G+     K  +   P Y  G
Sbjct: 19565 I---NKAGP--GKPSDASKAAYARDPQYPPG 19590



 Score =  101 bits (252), Expect = 7e-21
 Identities = 308/1501 (20%), Positives = 533/1501 (35%), Gaps = 204/1501 (13%)

Query: 624   NSHPIQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNS--YTIKGLKPGVVYE 678
             NS  + W  P+    S I +YIL  R K S  RW +      ++   + + GL  G  YE
Sbjct: 28166 NSITLTWARPESDGGSEIQQYILERREKKST-RWVKVISKRPISETRFKVTGLTEGNEYE 28224

Query: 679   GQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVV 738
               +++    G    +           PV          P  P V     VT+ + ++  +
Sbjct: 28225 FHVMAENAAGVGPASGIS-RLIKCREPVNP--------PGPPTVV---KVTDTSKTTVSL 28272

Query: 739   SW----VSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQIS 794
              W          + G+ +E   ++ GD  +        T   + DL  G +Y   V  I+
Sbjct: 28273 EWSKPVFDGGMEIIGYIIEMCKADLGDWHKVNAEACVKTRYTVTDLQAGEEYKFRVSAIN 28332

Query: 795   EDGEQSLILSTSQTTAPD--APPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGS 852
               G+      T    A D    P+  +D     + VVR          Y+   +P+   S
Sbjct: 28333 GAGKGDSCEVTGTIKAVDRLTAPELDIDANFKQTHVVRAGASIRLFIAYQGRPTPTAVWS 28392

Query: 853   STELNLPETANSVTLSDLQPGVQYNIT-------IYAVEENQESTPVVIQQETTGTPRSD 905
               + NL   A+  T          N            VE N  S  +    +   TP   
Sbjct: 28393 KPDSNLSLRADIHTTDSFSTLTVENCNRNDAGKYTLTVENNSGSKSITFTVKVLDTPGP- 28451

Query: 906   TVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPGEHGQRLPISRNTF 961
                 P  + F +VT    T+MW  P     + +  Y V+    +           +R  F
Sbjct: 28452 ----PGPITFKDVTRGSATLMWDAPLLDGGARIHHYVVEKREASRRSWQVISEKCTRQIF 28507

Query: 962   AEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQ----TTKLDAPTNLQFVNETDSTVLVRW 1017
              +V  L+ GV YYF+V AV+     +P    +    T +   P  L  V+ + S+ ++ W
Sbjct: 28508 -KVNDLAEGVPYYFRVSAVNEYGVGEPYEMPEPIVATEQPAPPRRLDVVDTSKSSAVLAW 28566

Query: 1018  TPP----RAQITGYRLTVGLTRRGQPRQYNVGPSVS-KYPLRNLQPASEY---------- 1062
               P     ++ITGY L   + ++G       G +    + +  L   +EY          
Sbjct: 28567 LKPDHDGGSRITGYLLE--MRQKGSDFWVEAGHTKQLTFTVERLVEKTEYEFRVKAKNDA 28624

Query: 1063  -------TVSLVAIKGNQESPKA--TGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRI 1113
                      S V IK  Q  P A  TG+   L    +  P+  +V      I+  PAP++
Sbjct: 28625 GYSEPREAFSSVIIKEPQIEPTADLTGITNQLITCKAGSPFTIDVP-----ISGRPAPKV 28679

Query: 1114  GFKL-GVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVT 1172
              +KL  +R  +        T D  ++ V     G    Y + +      +   +   V+ 
Sbjct: 28680 TWKLEEMRLKETDRVSITTTKDRTTLTVKDSMRGDSGRYFLTLENTAGVKTFSVTVVVIG 28739

Query: 1173  PLSPPTNLHLEANPDTGVLTVSW---ERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQ 1229
                P T     ++       +SW   +     +IT Y +    +       +   V   Q
Sbjct: 28740 RPGPVTGPIEVSSVSAESCVLSWGEPKDGGGTEITNYIVEKRESGTTAWQLVNSSVKRTQ 28799

Query: 1230  SSCTFDNLSPGLEYNVSV-----YTVKDDKESVPISDTIIPAVPP--PTDLRFTNIGPDT 1282
                T  +L+  +EY+  V     + V    ES PI     P VPP  PT     ++  + 
Sbjct: 28800 IKVT--HLTKYMEYSFRVSSENRFGVSKPLESAPII-AEHPFVPPSAPTRPEVYHVSANA 28856

Query: 1283  MRVTWAPPPSIDLTNFLVRYSPVKNEED----VAELSISPSDNAVVLTNLLPGTE----- 1333
             M + W  P   D  + ++ Y   K E +    V E  +   +    +T L+ G E     
Sbjct: 28857 MSIRWEEPYH-DGGSKIIGYWVEKKERNTILWVKENKVPCLECNYKVTGLVEGLEYQFRT 28915

Query: 1334  YVVSVSSVYEQHE-STPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPR----ATITGY 1388
             Y ++ + V +  E S P+  +    +D+P   + +D+T ++ ++ W AP     + + GY
Sbjct: 28916 YALNAAGVSKASEASRPIMAQNP--VDAPGRPEVTDVTRSTVSLIWSAPAYDGGSKVVGY 28973

Query: 1389  RIRHHPEHFSGRPREDRVPH---SRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQS 1445
              I   P    G  R  +  +   S N  T+T L+ G  Y   ++A N      +  G +S
Sbjct: 28974 IIERKPVSEVGDGRWLKCNYTIVSDNFFTVTALSEGDTYEFRVLAKNA--AGVISKGSES 29031

Query: 1446  TVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATI 1505
             T     RD            +  D   +      +     GG    +     G K     
Sbjct: 29032 TGPVTCRDEYAPPKAELDARLHGDLVTIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLC 29091

Query: 1506  SGLKPGVDYT----ITVYAVTGRGDS---------PASSKPISINYRTEIDKP---SQMQ 1549
                K  + YT      V     R DS          + +K +S+  +  +D P    ++ 
Sbjct: 29092 E--KVSLQYTGKRATAVIKFCDRSDSGKYTLTVKNASGTKAVSVMVKV-LDSPGPCGKLT 29148

Query: 1550  VTDVQDNSISVKW-LP---SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPT 1605
             V+ V     ++ W LP     + +T Y V           + +T+  +   + +EG  PT
Sbjct: 29149 VSRVTQEKCTLAWSLPQEDGGAEITHYIV----------ERRETSRLNW--VIVEGECPT 29196

Query: 1606  VEYVVS-----------VYAQNPSG-----ESQPLVQTAVTNIDRPKGL-AFTDVDVDSI 1648
             + YVV+           V A N  G     ES+P+V      I  P G+        + I
Sbjct: 29197 LSYVVTRLIKNNEYIFRVRAVNKYGPGVPVESEPIVARNSFTIPSPPGIPEEVGTGKEHI 29256

Query: 1649  KIAWESPQ----GQVSRYRVTYSSPED----GIHELFPAPDGEEDTAELQGLRPGSEYTV 1700
              I W  P+     ++S Y V     +      +++ +   D      ++  L  G +Y  
Sbjct: 29257 IIQWTKPESDGGNEISNYLVDKREKKSLRWTRVNKDYVVYD---TRLKVTSLMEGCDYQF 29313

Query: 1701  SVVALHDDMESQP------LIGTQSTAIPAPTDL-KFTQVTPTSLSAQWTPP----NVQL 1749
              V A++    S+P      +   + +  P P    +    T  S+S  WT P       +
Sbjct: 29314 RVTAVNAAGNSEPSEASNFISCREPSYTPGPPSAPRVVDTTKHSISLAWTKPMYDGGTDI 29373

Query: 1750  TGYRVRVTPKEKTGPMK-EINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGV- 1807
              GY + +  K+     +   N    ++   V  L +  KY   V A+     S  ++ + 
Sbjct: 29374 VGYVLEMQEKDTDQWYRVHTNATIRNTEFTVPDLKMGQKYSFRVAAVNVKGMSEYSESIA 29433

Query: 1808  -VTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPA-----NGQTPIQRTI 1861
              +  +E +  P    + D  + T+TI        +        P       G     R I
Sbjct: 29434 EIEPVERIEIP-DLELADDLKKTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAI 29492

Query: 1862  KPDVRSYTITGLQPGTDYKIYLYTL---NDNARSSPVVIDASTAIDAP-SNLRFLATTPN 1917
                  SY++  +     Y    YT+   N + + S  V+        P  +++    + +
Sbjct: 29493 IDTTESYSLLIVDKVNRYDAGKYTIEAENQSGKKSATVLVKVYDTPGPCPSVKVKEVSRD 29552

Query: 1918  SLLVSWQPPR----ARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYV 1973
             S+ ++W+ P     A +  YI++  +      + V   +   T   I+GL  GT Y   V
Sbjct: 29553 SVTITWEIPTIDGGAPVNNYIVEKREAAMRAFKTV-TTKCSKTLYRISGLVEGTMYYFRV 29611

Query: 1974  I 1974
             +
Sbjct: 29612 L 29612



 Score =  101 bits (252), Expect = 7e-21
 Identities = 364/1780 (20%), Positives = 631/1780 (35%), Gaps = 317/1780 (17%)

Query: 624   NSHPIQWNAPQPSHISKYILRW---RPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQ 680
             N+  I+W  P     SK I  W   + +N++   KE  +P    +Y + GL  G+ Y+ +
Sbjct: 28855 NAMSIRWEEPYHDGGSKIIGYWVEKKERNTILWVKENKVPCLECNYKVTGLVEGLEYQFR 28914

Query: 681   LISIQQYGHQEVTRFDFTTTSTSTPVTS-NTVTGETTPFSPLVATSESVTEITASSFVVS 739
               ++   G  + +         S P+ + N V     P          VT++T S+  + 
Sbjct: 28915 TYALNAAGVSKASE-------ASRPIMAQNPVDAPGRP---------EVTDVTRSTVSLI 28958

Query: 740   WVSAS----DTVSGFRVEYELSEEGDEPQYLDLPSTATSVN---IPDLLPGRKYIVNVYQ 792
             W + +      V G+ +E +   E  + ++L    T  S N   +  L  G  Y   V  
Sbjct: 28959 WSAPAYDGGSKVVGYIIERKPVSEVGDGRWLKCNYTIVSDNFFTVTALSEGDTYEFRVLA 29018

Query: 793   ISEDGEQSLILSTSQTTAPD------APPDPTVD-QVDDTSIVVRWSRPQAPITGYRIVY 845
              +  G   +I   S++T P       APP   +D ++    + +R         G  +V 
Sbjct: 29019 KNAAG---VISKGSESTGPVTCRDEYAPPKAELDARLHGDLVTIR--------AGSDLVL 29067

Query: 846   SPSVEGS----------STELNLPETANS----------VTLSDLQPGVQYNITIYAVEE 885
               +V G             EL+L E  +           +   D     +Y +T+     
Sbjct: 29068 DAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSGKYTLTVKNASG 29127

Query: 886   NQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDV 941
              +  + +V   ++ G     TV          VT  K T+ W+ P+    + +T Y V+ 
Sbjct: 29128 TKAVSVMVKVLDSPGPCGKLTVS--------RVTQEKCTLAWSLPQEDGGAEITHYIVE- 29178

Query: 942   IPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYY-----------FKVFAVS-HGR----E 985
                        R   SR  +  V G  P ++Y            F+V AV+ +G     E
Sbjct: 29179 -----------RRETSRLNWVIVEGECPTLSYVVTRLIKNNEYIFRVRAVNKYGPGVPVE 29227

Query: 986   SKPLTAQQTTKLDAPTNL-QFVNETDSTVLVRWTPPRA----QITGYRLTVGLTRRGQPR 1040
             S+P+ A+ +  + +P  + + V      ++++WT P +    +I+ Y   V    +   R
Sbjct: 29228 SEPIVARNSFTIPSPPGIPEEVGTGKEHIIIQWTKPESDGGNEISNY--LVDKREKKSLR 29285

Query: 1041  QYNVGPSVSKYPLR----NLQPASEYTVSLVAIK--GNQESPKATGVFTTLQPGSSI-PP 1093
                V      Y  R    +L    +Y   + A+   GN E  +A+   +  +P  +  PP
Sbjct: 29286 WTRVNKDYVVYDTRLKVTSLMEGCDYQFRVTAVNAAGNSEPSEASNFISCREPSYTPGPP 29345

Query: 1094  YNTEVTETT---IVITWTP------APRIGFKLGVRPSQGGEAPR---EVTSDSGSIVVS 1141
                 V +TT   I + WT          +G+ L ++     +  R     T  +    V 
Sbjct: 29346 SAPRVVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDTDQWYRVHTNATIRNTEFTVP 29405

Query: 1142  GLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPD---TGVLTVSWERS 1198
              L  G +Y + +  +      +       + P+       LE   D   T  +       
Sbjct: 29406 DLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEIPDLELADDLKKTVTIRAGASLR 29465

Query: 1199  TTPDITGYRITTTPTNGQQGNSLEEVVHADQS-SCTFDNLSPGLEYNVSVYTVKDDKESV 1257
                 ++G R     T  +QG  L      D + S +   +     Y+   YT++ + +S 
Sbjct: 29466 LMVSVSG-RPPPVITWSKQGIDLASRAIIDTTESYSLLIVDKVNRYDAGKYTIEAENQSG 29524

Query: 1258  PISDTIIPAV----PPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAE 1313
               S T++  V     P   ++   +  D++ +TW  P +ID    +  Y   K E  +  
Sbjct: 29525 KKSATVLVKVYDTPGPCPSVKVKEVSRDSVTITWEIP-TIDGGAPVNNYIVEKREAAMRA 29583

Query: 1314  ---LSISPSDNAVVLTNLLPGTEYVVSV--SSVY---EQHESTPLRGRQKTGLDSPTGID 1365
                ++   S     ++ L+ GT Y   V   ++Y   E  E++      +  L  P  ++
Sbjct: 29584 FKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYGIGEPCETSDAVLVSEVPL-VPAKLE 29642

Query: 1366  FSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRNSI---TLTNL 1418
               D+T ++ T+ W  P     + +TGY +       +G  R  +V   + ++   T+T+L
Sbjct: 29643 VVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACK---AGTERWMKVVTLKPTVLEHTVTSL 29699

Query: 1419  TPGTEYVVSIVALNGREESPLLIGQQSTVSDVP-RDLEVVAATPTSLLISWDAPAVTVRY 1477
               G +Y+  I A N +  S      + TV+ V  +DL V+     S +          R 
Sbjct: 29700 NEGEQYLFRIRAQNEKGVSE----PRETVTAVTVQDLRVLPTIDLSTMPQKTIHVPAGRP 29755

Query: 1478  YRITYGETGGNSPVQEFTVPGSKS-----------------TATISGLKPGVDYTITVYA 1520
               +     G   P   +   GSK                  T   + ++   +YT+ +  
Sbjct: 29756 VELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAKLTIRETTIRDTGEYTLELKN 29815

Query: 1521  VTGRGDSPASSKPISINYRTEIDKPSQ----MQVTDVQDNSISVKWLP----SSSPVTGY 1572
             VTG      +S+ I +     +DKP      +++ ++   SI++ W P      +P++GY
Sbjct: 29816 VTG-----TTSETIKVII---LDKPGPPTGPIKIDEIDATSITISWEPPELDGGAPLSGY 29867

Query: 1573  RVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPL------VQ 1626
              V     + PG      +    T      L    EYV  V A N  G    L       +
Sbjct: 29868 VVEQRDAHRPGWLPVSESVTRST-FKFTRLTEGNEYVFRVAATNRFGIGSYLQSEVIECR 29926

Query: 1627  TAVTNIDRPKGLAFTDVDVDSIKIAWESPQ----GQVSRYRVTYSSPEDGIHELFPAPDG 1682
             +++     P+ L   DV  D + + W  P+     QV+ Y V                  
Sbjct: 29927 SSIRIPGPPETLQIFDVSRDGMTLTWYPPEDDGGSQVTGYIVERKEVRADRWVRVNKVPV 29986

Query: 1683  EEDTAELQGLRPGSEYTVSVVALH------DDMESQPLIGTQSTAIPA-PTDLKFTQVTP 1735
                     GL  G EY   V A++          S+P++     A P  P + + T  T 
Sbjct: 29987 TMTRYRSTGLTEGLEYEHRVTAINARGSGKPSRPSKPIVAMDPIAPPGKPQNPRVTDTTR 30046

Query: 1736  TSLSAQWTPPNVQ----LTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVS 1791
             TS+S  W+ P  +    +TGY + +   ++    K            ++ L    +Y   
Sbjct: 30047 TSVSLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTKCNTTPTKIREYTLTHLPQGAEYRFR 30106

Query: 1792  VYALKDTLTSRPAQ--GVVTTLENVSPP---------RRARVTDATETTITISWRTKTET 1840
             V A        PA+  G V   E +  P             V       +TI  + K   
Sbjct: 30107 VLACNAGGPGEPAEVPGTVKVTEMLEYPDYELDERYQEGIFVRQGGVIRLTIPIKGKP-- 30164

Query: 1841  ITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGT--DYKIYLYTLNDNARSSPVVID 1898
                F +      GQ   +R +     ++T   ++     D   Y   L +      V I 
Sbjct: 30165 ---FPICKWTKEGQDISKRAMIATSETHTELVIKEADRGDSGTYDLVLENKCGKKAVYIK 30221

Query: 1899  ASTAIDAPSN----LRFLATTPNSLLVSWQPPR----ARITGYII-KYEKPGSPPREVVP 1949
                 I +P++    L +      S+ VSW+PP     A I GYI+ + E P +    +  
Sbjct: 30222 VRV-IGSPNSPEGPLEYDDIQVRSVRVSWRPPADDGGADILGYILERREVPKAAWYTIDS 30280

Query: 1950  RPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQKTPFVTHPGYDTGNGI 2009
             R R   T   + GL+   EY   V A      S+PL   +    KTP             
Sbjct: 30281 RVRG--TSLVVKGLKENVEYHFRVSAENQFGISKPLKSEEPVTPKTPL------------ 30326

Query: 2010  QLPGTSGQQPSVGQQMIFEEHGFRRTTPPTTATPIRHRPRPYPPNVGQEALSQTTISWAP 2069
                                        PP         P   PP V     S  ++SW+ 
Sbjct: 30327 --------------------------NPP--------EPPSNPPEVLDVTKSSVSLSWSR 30352

Query: 2070  FQD-----TSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKD--- 2121
              +D      + Y I      TD+     +   T+T  T+TGL   A Y   + A  D   
Sbjct: 30353 PKDDGGSRVTGYYIERKETSTDKWVRHNKTQITTTMYTVTGLVPDAEYQFRIIAQNDVGL 30412

Query: 2122  QQRHKVREEVVTVGNSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLG 2181
              +     E VV       +  ++P+     +  ++S  +V  +WE+    G K   + LG
Sbjct: 30413 SETSPASEPVV-----CKDPFDKPSQPGELEILSISKDSVTLQWEKPECDGGK---EILG 30464

Query: 2182  FGSGHFRCDSSRWCHDNGVNYKIGEKWDRQGENGQMMSCT 2221
             +   + +   S W   N    K     D+Q   G ++  T
Sbjct: 30465 YWVEYRQSGDSAWKKSNKERIK-----DKQFTIGGLLEAT 30499



 Score = 99.8 bits (247), Expect = 3e-20
 Identities = 305/1551 (19%), Positives = 537/1551 (34%), Gaps = 252/1551 (16%)

Query: 610   GPVEVFITETPSQPNSHPIQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSY 666
             GPV        ++ + H + W  P+    S ++ YI+  R  +    W   T      S+
Sbjct: 18700 GPVSDLKVSDVTKTSCH-VSWAPPENDGGSQVTHYIVEKREADRK-TWSTVTPEVKKTSF 18757

Query: 667   TIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSE 726
              +  L PG  Y  ++ ++ +YG           T    PV ++    E  P   L     
Sbjct: 18758 HVTNLVPGNEYYFRVTAVNEYG-------PGVPTDVPKPVLASDPLSEPDPPRKL----- 18805

Query: 727   SVTEITASSFVVSWV----SASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLP 782
              VTE+T +S  ++W+         + G+   Y   E+  +           S+ +  L  
Sbjct: 18806 EVTEMTKNSATLAWLPPLRDGGAKIDGYITSYREEEQPADRWTEYSVVKDLSLVVTGLKE 18865

Query: 783   GRKY-----IVNVYQISEDGEQSLILSTSQTTAPD---APPDPTVDQVDDTSIVVRWSRP 834
             G+KY       N   +S   E   +    +   P     P   T+       I       
Sbjct: 18866 GKKYKFRVAARNAVGVSLPREAEGVYEAKEQLLPPKILMPEQITIKAGKKLRIEAHVYGK 18925

Query: 835   QAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDL--QPGVQYNITIYAVEENQESTPV 892
               P   ++      V  S   ++  ++++ + + D+  +    Y++T             
Sbjct: 18926 PHPTCKWKKGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIK 18985

Query: 893   VIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPG 948
             V+  +  G P+      P D+  ++      ++ W  P     S +T Y V+   V+  G
Sbjct: 18986 VVVMDAPGPPQ-----PPFDISDIDAD--ACSLSWHIPLEDGGSNITNYIVEKCDVS-RG 19037

Query: 949   EHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKL------DAPTN 1002
             +    L     T   V  L PG  Y F+V A +    S+PLT+ +            P N
Sbjct: 19038 DWVTALASVTKTSCRVGKLIPGQEYIFRVRAENRFGISEPLTSPKMVAQFPFGVPSEPKN 19097

Query: 1003  LQFVNETDSTVLVRWTPPRAQ----ITGYRLTVGLTRRGQPRQYNVGPSV---SKYPLRN 1055
              +        + V W  P +     I GY   +    R          ++   ++YP   
Sbjct: 19098 ARVTKVNKDCIFVAWDRPDSDGGSPIIGY--LIERKERNSLLWVKANDTLVRSTEYPCAG 19155

Query: 1056  LQPASEYTVSLVAIKGNQESP--KATGVFTTLQPGSSIPPYNTE---VTETTIVITWT-P 1109
             L    EY+  + A+     SP  K T   T   P    PP   E   VT++T+ + W  P
Sbjct: 19156 LVEGLEYSFRIYALNKAGSSPPSKPTEYVTARMPVD--PPGKPEVIDVTKSTVSLIWARP 19213

Query: 1110  APRIGFKL-----------GVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVY------- 1151
                 G K+           G +  +   AP ++  +      +GL    +Y +       
Sbjct: 19214 KHDGGSKIIGYFVEACKLPGDKWVRCNTAPHQIPQE--EYTATGLEEKAQYQFRAIARTA 19271

Query: 1152  -------------TIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANP-DTGVLTVSWER 1197
                          TI         D  +  K +  +   TN+ L+A      + TVSW++
Sbjct: 19272 VNISPPSEPSDPVTILAENVPPRIDLSVAMKSLLTVKAGTNVCLDATVFGKPMPTVSWKK 19331

Query: 1198  STTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFD----NLSPGLEYNVSVYTVKDD 1253
               T           P  G +       +   ++ CT +    N     +Y ++       
Sbjct: 19332 DGT--------LLKPAEGIK-------MAMQRNLCTLELFSVNRKDSGDYTITAENSSGS 19376

Query: 1254  KESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPP---PSIDLTNFLVRYSPVKNEED 1310
             K S  I   ++    PP  ++   +  D   ++W PP      ++TN++V      +  +
Sbjct: 19377 K-SATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYIVDKRET-SRPN 19434

Query: 1311  VAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPL---RGRQKTGLDSPTGID-- 1365
              A++S +    +  +  L+ G EY   + +  +     P+       K   D P   D  
Sbjct: 19435 WAQVSATVPITSCSVEKLIEGHEYQFRICAENKYGVGDPVFTEPAIAKNPYDPPGRCDPP 19494

Query: 1366  -FSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTP 1420
               S+IT +  TV W  P     + ITGY +           + +R P    ++  T L  
Sbjct: 19495 VISNITKDHMTVSWKPPADDGGSPITGYLLEKRETQAVNWTKVNRKPIIERTLKATGLQE 19554

Query: 1421  GTEYVVSIVALNGREESPLLIGQQSTVSDV------------PRDLEVVAATPTSLLISW 1468
             GTEY   + A+N  +  P   G+ S  S              P   +V   T +S+ +SW
Sbjct: 19555 GTEYEFRVTAIN--KAGP---GKPSDASKAAYARDPQYPPGPPAFPKVYDTTRSSVSLSW 19609

Query: 1469  DAPAV----TVRYYRITYGETGGNSPVQEFTVPGS--KSTATISGLKPGVDYTITVYAVT 1522
               PA      +  Y +       ++ V+   +P +  K+   ++GL     Y   VYAV 
Sbjct: 19610 GKPAYDGGSPIIGYLVEVKRADSDNWVR-CNLPQNLQKTRFEVTGLMEDTQYQFRVYAVN 19668

Query: 1523  GRG-----DSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTT 1577
               G     D P    P  I    E +  + ++ T +    ++++      PV G      
Sbjct: 19669 KIGYSDPSDVPDKHYPKDILIPPEGELDADLRKTLILRAGVTMRLY---VPVKGRPPPKI 19725

Query: 1578  PKNGPGPTKTKTAGPD------QTEMTIEGLQ--PTVEYVVSVYAQNPSGESQPLVQTAV 1629
               + P        G D       T +  E +      +Y++++  +N  G+ +  +   V
Sbjct: 19726 TWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKYILTL--ENSCGKKEYTIVVKV 19783

Query: 1630  TNIDRPK-GLAFTDVDVDSIKIAWESP----QGQVSRYRVTYSSPEDGIHELFPAPDGEE 1684
              +   P   +   ++  DS  + WE P       +  Y V     E          +  +
Sbjct: 19784 LDTPGPPVNVTVKEISKDSAYVTWEPPIIDGGSPIINYVVQKRDAERKSWSTV-TTECSK 19842

Query: 1685  DTAELQGLRPGSEYTVSVVA-----LHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLS 1739
              +  +  L  G  Y   V A     + D  E++  +    T  P   DLK   V+ +S S
Sbjct: 19843 TSFRVANLEEGKSYFFRVFAENEYGIGDPGETRDAVKASQTPGPV-VDLKVRSVSKSSCS 19901

Query: 1740  AQWTPPN----VQLTGYRVRVTPKEKTGP--MKEINLAPDSSSVVVSGLMVATKYEVSVY 1793
               W  P+     ++ GY V    +E      MK ++L   +       L    +Y   V 
Sbjct: 19902 IGWKKPHSDGGSRIIGYVVDFLTEENKWQRVMKSLSLQYSAKD-----LTEGKEYTFRVS 19956

Query: 1794  ALKDTLTSRPAQGVVTTLENVSPPR-------------------RARVTDATETTITISW 1834
             A  +     P++  V   ++V  P                    R ++    +   ++SW
Sbjct: 19957 AENENGEGTPSEITVVARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPIKGKPAPSVSW 20016

Query: 1835  RTKTE---TITGFQVDAVPANGQTPIQRTIKPDVRSYTIT-----GLQPGTDYKIYLYTL 1886
             +   +   T T   V++   N    +    K D   YTIT     G + GT         
Sbjct: 20017 KKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKEGT--------- 20067

Query: 1887  NDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGS 1942
                   S  V+        P  ++F   T  ++ + W PP+    + IT YI++ ++   
Sbjct: 20068 -----ISIKVVGKPGIPTGP--IKFDEVTAEAMTLKWAPPKDDGGSEITNYILE-KRDSV 20119

Query: 1943  PPREVVPRPRPGVTEATITGLEPGTEYTIYVIA-----LKNNQKSEPLIGR 1988
               + V        T   +T L  G EYT  V A     +    KSEP++ R
Sbjct: 20120 NNKWVTCASAVQKTTFRVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVAR 20170



 Score = 96.7 bits (239), Expect = 2e-19
 Identities = 334/1533 (21%), Positives = 553/1533 (36%), Gaps = 218/1533 (14%)

Query: 619   TPSQPNSHPIQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGV 675
             T S  +S  +QWN P     S +  Y L  + +NS+   K    P     +   GL+ GV
Sbjct: 22350 TLSSRDSMEVQWNEPISDGGSRVIGYHLERKERNSILWVKLNKTPIPQTKFKTTGLEEGV 22409

Query: 676   VYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASS 735
              YE ++ +    G                P   +       P  P     E++  +T +S
Sbjct: 22410 EYEFRVSAENIVG-------------IGKPSKVSECYVARDPCDP-PGRPEAII-VTRNS 22454

Query: 736   FVVSW----VSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVY 791
               + W          ++G+ VE +   EG   +        T   +  L+   +Y   V 
Sbjct: 22455 VTLQWKKPTYDGGSKITGYIVEKKELPEGRWMKASFTNIIDTHFEVTGLVEDHRYEFRVI 22514

Query: 792   QISEDGEQSLIL-STSQTTAPDA--PPDPTVDQVDDTSIVVRWS---RPQAPITGYRIVY 845
               +  G  S    ST   TA D   PP  ++D     +IVV      +  A I G  I  
Sbjct: 22515 ARNAAGVFSEPSESTGAITARDEVDPPRISMDPKYKDTIVVHAGESFKVDADIYGKPI-- 22572

Query: 846   SPSVEGSSTELNLPETAN-SVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRS 904
              P+++    +  L  TA   +  +D    +     +       +S   +++ +     RS
Sbjct: 22573 -PTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRV-----DSGNYILKAKNVAGERS 22626

Query: 905   DTV-------PSPRDLQFV--EVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLP 955
              TV       P P +   V   VT  K T+ W PP   +     D+I   +      RL 
Sbjct: 22627 VTVNVKVLDRPGPPEGPVVISGVTAEKCTLAWKPP---LQDGGSDIINYIVERRETSRLV 22683

Query: 956   IS------RNTFAEVTGLSPGVTYYFKVFAVS-----HGRESKPLTAQQTTKL-DAPTNL 1003
              +      +    +VT L  G  Y F++ AV+        ES+P+ A+    + DAP   
Sbjct: 22684 WTVVDANVQTLSCKVTKLLEGNEYTFRIMAVNKYGVGEPLESEPVVAKNPFVVPDAPKAP 22743

Query: 1004  QFVNETDSTVLVRWTPPRA----QITGYRLTV----GLTRRGQPRQYNVGPSVSKYPLRN 1055
             +    T  +++V W  P +    +I GY L      G+ R  +  +  +G    +     
Sbjct: 22744 EVTTVTKDSMIVVWERPASDGGSEILGYVLEKRDKEGI-RWTRCHKRLIGELRLRVTGLI 22802

Query: 1056  LQPASEYTVSLVAIKGNQE-SPKAT---GVFTTLQPGSSIPPYNTEVTETTIVITWTPAP 1111
                  E+ VS     G  E SP +          +PG    P   ++T +++ ++W+   
Sbjct: 22803 ENHDYEFRVSAENAAGLSEPSPPSAYQKACDPIYKPGPPNNPKVIDITRSSVFLSWSKPI 22862

Query: 1112  RIGF---------KLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRD---G 1159
               G          K  V   +          +  +I V  L    EY + I  +     G
Sbjct: 22863 YDGGCEIQGYIVEKCDVSVGEWTMCTPPTGINKTNIEVEKLLEKHEYNFRICAINKAGVG 22922

Query: 1160  QERDAPIVNKVVTPL-SPPTNLHLEANPDTGV-------LTVSWERSTTPDITGYRITTT 1211
             +  D P    V   L +P  +L LE      +       L V  +   TP++   ++   
Sbjct: 22923 EHADVPGPIIVEEKLEAPDIDLDLELRKIINIRAGGSLRLFVPIKGRPTPEVKWGKV--- 22979

Query: 1212  PTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTV----KDDKESVPISDTIIPAV 1267
               +G+  ++    V +  +S   DN++    Y+   YT+        +S  ++  ++   
Sbjct: 22980 --DGEIRDAAIIDVTSSFTSLVLDNVN---RYDSGKYTLTLENSSGTKSAFVTVRVLDTP 23034

Query: 1268  PPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNE---EDVAELSISPSDNAVV 1324
              PP +L+ T I  D++ +TW  PP +D  + +  Y   K E   +  A +  +   N+  
Sbjct: 23035 SPPVNLKVTEITKDSVSITW-EPPLLDGGSKIKNYIVEKREATRKSYAAVVTNCHKNSWK 23093

Query: 1325  LTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGL----DSPTGIDFSDITANSFTVHWIA 1380
             +  L  G  Y   V++  E     P +      +      P  I   D+T NS ++ W  
Sbjct: 23094 IDQLQEGCSYYFRVTAENEYGIGLPAQTADPIKVAEVPQPPGKITVDDVTRNSVSLSWTK 23153

Query: 1381  PR----ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREE 1436
             P     + I  Y +    +H        RV   +    +TNLT G EY+  +VA+N +  
Sbjct: 23154 PEHDGGSKIIQYIVEMQAKHSEKWSECARVKSLQ--AVITNLTQGEEYLFRVVAVNEKGR 23211

Query: 1437  S-PLLIGQQSTVSDVPRDLEVVAA-TPTSLLISWD----APAVTVRYYRITYGETGGNSP 1490
             S P  +       D+  + +V  A +  S+ +  D     P        IT+ + G   P
Sbjct: 23212 SDPRSLAVPIVAKDLVIEPDVKPAFSSYSVQVGQDLKIEVPISGRPKPTITWTKDG--LP 23269

Query: 1491  VQEFT---VPGSKSTATIS----GLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEID 1543
             +++ T   V  S    T+S        G  Y ITV  V G+       K  SI   T +D
Sbjct: 23270 LKQTTRINVTDSLDLTTLSIKETHKDDGGQYGITVANVVGQ-------KTASIEIVT-LD 23321

Query: 1544  KP----SQMQVTDVQDNSISVKWLP----SSSPVTGYRV-----TTTPKNGPGPTKTKTA 1590
             KP      ++  DV   SI++ W P        +T Y V     TTT  +    T  +T 
Sbjct: 23322 KPDPPKGPVKFDDVSAESITLSWNPPLYTGGCQITNYIVQKRDTTTTVWDVVSATVARTT 23381

Query: 1591  GPDQTEMTIEGLQPTVEYVVSVYAQNPSG-----ESQPLVQTAVTNIDRPKGLAF-TDVD 1644
                   + +  L+   EY   ++A+N  G     ES P+V         P G  F T + 
Sbjct: 23382 ------LKVTKLKTGTEYQFRIFAENRYGQSFALESDPIVAQYPYKEPGPPGTPFATAIS 23435

Query: 1645  VDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGE---EDTA-ELQGLRPGSEYTV 1700
              DS+ I W  P        + Y       + +      +    DT  + Q L  G EY  
Sbjct: 23436 KDSMVIQWHEPVNNGGSPVIGYHLERKERNSILWTKVNKTIIHDTQFKAQNLEEGIEYEF 23495

Query: 1701  SVVALHDDMESQPLIGTQSTAIPAPTDLKFT----QVTPTSLSAQWTPP----NVQLTGY 1752
              V A +     +    ++      P D   T     V    ++ QWT P       +TGY
Sbjct: 23496 RVYAENIVGVGKASKNSECYVARDPCDPPGTPEPIMVKRNEITLQWTKPVYDGGSMITGY 23555

Query: 1753  RVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDT-LTSRPAQ--GVVT 1809
              V          MK        +   VSGL    +YE  V A       S+P+   G +T
Sbjct: 23556 IVEKRDLPDGRWMKASFTNVIETQFTVSGLTEDQRYEFRVIAKNAAGAISKPSDSTGPIT 23615

Query: 1810  TLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYT 1869
               + V  PR +      +T +  +  T       F+++A       P    ++ D     
Sbjct: 23616 AKDEVELPRISMDPKFRDTIVVNAGET-------FRLEADVHGKPLPTIEWLRGDKEIEE 23668

Query: 1870  ITGLQ-PGTDYKIYL------------YTLNDN----ARSSPV---VIDASTAIDAPSNL 1909
                 +   TD+K  L            Y L  +    ++S PV   V+D     + P  +
Sbjct: 23669 SARCEIKNTDFKALLIVKDAIRIDGGQYILRASNVAGSKSFPVNVKVLDRPGPPEGP--V 23726

Query: 1910  RFLATTPNSLLVSWQPP----RARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEP 1965
             +    T     ++W PP     + I+ Y+++ ++  S     V           +T L  
Sbjct: 23727 QVTGVTSEKCSLTWSPPLQDGGSDISHYVVE-KRETSRLAWTVVASEVVTNSLKVTKLLE 23785

Query: 1966  GTEYTIYVIALKNNQKSEPLIGRKKTVQKTPFV 1998
             G EY   ++A+      EPL      + K PFV
Sbjct: 23786 GNEYVFRIMAVNKYGVGEPL-ESAPVLMKNPFV 23817



 Score = 93.6 bits (231), Expect = 2e-18
 Identities = 287/1440 (19%), Positives = 522/1440 (36%), Gaps = 175/1440 (12%)

Query: 675   VVYEGQLISIQQYGHQEVTRFDFTTTSTS--TPVTSNTVTGETT--PFSPLVATSESVTE 730
             +  E   I++++    +  R++ T  ++S  T    N V  +    P  P+V     +++
Sbjct: 26527 ITAENLTINLKESVTADAGRYEITAANSSGTTKAFINIVVLDRPGPPTGPVV-----ISD 26581

Query: 731   ITASSFVVSWVSAS-DTVSGFRVEYELSEEGDEPQYLDLPSTA--TSVNIPDLLPGRKY- 786
             IT  S  + W     D  S       L  E     + ++ +T   T + +  L  G +Y 
Sbjct: 26582 ITEESVTLKWEPPKYDGGSQVTNYILLKRETSTAVWTEVSATVARTMMKVMKLTTGEEYQ 26641

Query: 787   ----IVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYR 842
                   N + IS+  + + +      T P  P  P V  V   SI V W  P +   G  
Sbjct: 26642 FRIKAENRFGISDHIDSACVTVKLPYTTPGPPSTPWVTNVTRESITVGWHEPVS--NGGS 26699

Query: 843   IVYSPSVEGSSTELNLPETANSVTL-------SDLQPGVQYNITIYAVEENQESTPVVIQ 895
              V    +E       L + AN + +       + +  G+ Y   +YA        P    
Sbjct: 26700 AVVGYHLEMKDRNSILWQKANKLVIRTTHFKVTTISAGLIYEFRVYAENAAGVGKP---S 26756

Query: 896   QETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPVNLPGEHG 951
               +      D    PR+++  +++   V++ W  P     S +TGY V+    +LP    
Sbjct: 26757 HPSEPVLAIDACEPPRNVRITDISKNSVSLSWQQPAFDGGSKITGYIVE--RRDLPDGRW 26814

Query: 952   QRLPISRNTFAE--VTGLSPGVTYYFKVFAVSH-GRESKPL-TAQQTTKLDAPTNLQFVN 1007
              +   +  T  +  ++GL+    Y F+VFA +  G  S P       T +D+        
Sbjct: 26815 TKASFTNVTETQFIISGLTQNSQYEFRVFARNAVGSISNPSEVVGPITCIDSYGGPVIDL 26874

Query: 1008  ETDSTVLVRWTPPRAQITGYRLTVGLTRRGQP--RQYNVGPSVSKYPLRNLQPASEYTVS 1065
               + T +V++       T  +L  G++ +  P    Y     +    L  ++  ++    
Sbjct: 26875 PLEYTEVVKYRAG----TSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLASI 26930

Query: 1066  LV-------------AIKGNQESPKATGVFTTL-QPGSSIPPYNTE-VTETTIVITW-TP 1109
             L+              ++    S  AT     L +PG    P   + VT   I + W  P
Sbjct: 26931 LIKDADRLNSGCYELKLRNAMGSASATIRVQILDKPGPPGGPIEFKTVTAEKITLLWRPP 26990

Query: 1110  APRIGFKLGVRPSQGGEAPREVTS------DSGSIVVSGLTPGVEYVYTIQVLR-----D 1158
             A   G K+     +  E  R V S      +   I  + +  G EY++ ++ +      +
Sbjct: 26991 ADDGGAKITHYIVEKRETSRVVWSMVSEHLEECIITTTKIIKGNEYIFRVRAVNKYGIGE 27050

Query: 1159  GQERDAPIV-NKVVTPLSP--PTNLHLEANPDTGVLTVSWERSTT---PDITGYRITTTP 1212
               E D+ +  N  VTP  P  P    +  N     +TV W R       DI+GY +    
Sbjct: 27051 PLESDSVVAKNAFVTPGPPGIPEVTKITKNS----MTVVWSRPIADGGSDISGYFLEKRD 27106

Query: 1213  TNGQQG-NSLEEVVHADQSSCTFDNLSPGLEYNVSVYTV--------KDDKESVPISDTI 1263
                      L+E +   +   T   L+   +Y   V  V         +  E    +D I
Sbjct: 27107 KKSLGWFKVLKETIRDTRQKVT--GLTENSDYQYRVCAVNAAGQGPFSEPSEFYKAADPI 27164

Query: 1264  IPAVPPPTDLRFTNIGPDTMRVTWAPP---PSIDLTNFLVRYSPVKNEE-DVAELSISPS 1319
              P   PP  +R  +    ++ + W+ P       +T ++V     + EE           
Sbjct: 27165 DPP-GPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVVEIRQGEEEEWTTVSTKGEVR 27223

Query: 1320  DNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQ----KTGLDSPTGIDFSDITANSFT 1375
                 V++NL PG  Y   VS+V    +  P+   +    K  L++P  ID       S  
Sbjct: 27224 TTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQAKDILEAPE-IDLDVALRTSVI 27282

Query: 1376  VHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSI---------TLTNLTPGT--EY 1424
                      +  ++ R  P     +  ++    +R SI         T+  +T     +Y
Sbjct: 27283 AKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKY 27342

Query: 1425  VVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGE 1484
             +++I    G  +S  +  +        + L+V   +  ++ + WD P +      I Y  
Sbjct: 27343 ILTIENGVGEPKSSTVSVKVLDTPAACQKLQVKHVSRGTVTLLWDPPLIDGGSPIINYVI 27402

Query: 1485  TGGNSPVQEFTVPGSKSTATISGL-----KPGVDYTITVYAVTGRGDSPASSKPISINYR 1539
                ++  + ++V   K ++T   L     K    + +      G G+   +++P+     
Sbjct: 27403 EKRDATKRTWSVVSHKCSSTSFKLIDLSEKTPFFFRVLAENEIGIGEPCETTEPVK---A 27459

Query: 1540  TEIDKP-SQMQVTDVQDNSISVKW----LPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQ 1594
              E+  P   + + D    S+ + W        S +T Y V    + G G      AG  +
Sbjct: 27460 AEVPAPIRDLSMKDSTKTSVILSWTKPDFDGGSVITEYVV---ERKGKGEQTWSHAGISK 27516

Query: 1595  T-EMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFT-DVDVDSIKIAW 1652
             T E+ +  L+        V+A+N  G S P+    +T     K L  T +VD+  I  A 
Sbjct: 27517 TCEIEVSQLKEQSVLEFRVFAKNEKGLSDPVTIGPIT----VKELIITPEVDLSDIPGAQ 27572

Query: 1653  ESPQ-GQVSRYRVTY-SSPEDGIHEL---FPAPDGE-------EDTAELQGLRPGSEYTV 1700
              + + G      + Y   P+  I  L    P  + E       E+   L       E+  
Sbjct: 27573 VTVRIGHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGG 27632

Query: 1701  SVVALHDDMESQPLIGTQSTAIPAPT----DLKFTQVTPTSLSAQWTPP----NVQLTGY 1752
                 + D+   +  +      +  P+     ++F ++   S+   W  P      ++T Y
Sbjct: 27633 KYTVILDNAVCRIAVPITVITLGPPSKPKGPIRFDEIKADSVILSWDVPEDNGGGEITCY 27692

Query: 1753  RVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLE 1812
              +      +T   K +  +   ++  V  L+   +Y+  V A      S+P    +   +
Sbjct: 27693 SIEKRETSQTN-WKMVCSSVARTTFKVPNLVKDAEYQFRVRAENRYGVSQPLVSSIIVAK 27751

Query: 1813  N----VSPPRRARVTDATETTITISWRTKT----ETITGFQVDAVPANGQTPIQRTIKP- 1863
             +      PP +  + + T   ++++W          +TGF V+    N     +    P 
Sbjct: 27752 HQFRIPGPPGKPVIYNVTSDGMSLTWDAPVYDGGSEVTGFHVEKKERNSILWQKVNTSPI 27811

Query: 1864  DVRSYTITGLQPGTDYKIYLYTLNDNARSSP----VVIDASTAIDAPSNLRFLATTPNSL 1919
               R Y  TGL  G DY+  +Y  N    SSP        A + +D P    ++  T  ++
Sbjct: 27812 SGREYRATGLVEGLDYQFRVYAENSAGLSSPSDPSKFTLAVSPVDPPGTPDYIDVTRETI 27871

Query: 1920  LVSWQPP----RARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIA 1975
              + W PP     ++I GY I+ ++ G+              + T+TGL PG  Y   +IA
Sbjct: 27872 TLKWNPPLRDGGSKIVGYSIE-KRQGNERWVRCNFTDVSECQYTVTGLSPGDRYEFRIIA 27930



 Score = 92.8 bits (229), Expect = 3e-18
 Identities = 271/1344 (20%), Positives = 470/1344 (34%), Gaps = 199/1344 (14%)

Query: 628   IQWNAPQPS---HISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISI 684
             I W  P  +    IS YI+  R   +   W   +      +  I  LK G  Y+ ++ + 
Sbjct: 24424 ISWEPPAYTGGCQISNYIVEKRDTTTT-TWHMVSATVARTTIKITKLKTGTEYQFRIFAE 24482

Query: 685   QQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSAS 744
              +YG              S P+ S  V  +     P    +  VT I+    +V W    
Sbjct: 24483 NRYGK-------------SAPLDSKAVIVQYPFKEPGPPGTPFVTSISKDQMLVQWHEPV 24529

Query: 745   DTVSGFRVEYELSE-EGDEPQYLDLPSTA---TSVNIPDLLPGRKYI--VNVYQISEDGE 798
             +      + Y L + E +   ++ L  T    T      L  G +Y   V+   I   G+
Sbjct: 24530 NDGGTKIIGYHLEQKEKNSILWVKLNKTPIQDTKFKTTGLDEGLEYEFKVSAENIVGIGK 24589

Query: 799   QSLILSTSQTTAPDAPPD-PTVDQVDDTSIVVRWSRPQ----APITGYRIVYSPSVEG-- 851
              S +        P  PP  P    +   ++ ++W +P     + ITGY +      +G  
Sbjct: 24590 PSKVSECFVARDPCDPPGRPEAIVITRNNVTLKWKKPAYDGGSKITGYIVEKKDLPDGRW 24649

Query: 852   -SSTELNLPETANSVTLSDLQPGVQYNITIYA------VEENQESTPVVIQQETTGTPRS 904
               ++  N+ ET    T+S L    +Y   + A        E  +S+  +  ++    P +
Sbjct: 24650 MKASFTNVLET--EFTVSGLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARDEIDAPNA 24707

Query: 905   DTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPG----EHGQRLPISRNT 960
                P  +D+  V   +  V       E+ + G  +  +  +  G    E   R+ I ++T
Sbjct: 24708 SLDPKYKDVIVVHAGETFVL------EADIRGKPIPDVVWSKDGKELEETAARMEI-KST 24760

Query: 961   FAEVTGL------SPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTN-LQFVNETDSTV 1013
               + T +      + G  Y  K+  V  G +S P+T +   +   P   L+    T    
Sbjct: 24761 IQKTTLVVKDCIRTDGGQYILKLSNVG-GTKSIPITVKVLDRPGPPEGPLKVTGVTAEKC 24819

Query: 1014  LVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAI 1069
              + W PP     A I+ Y +    T R    Q +       Y +  L P +EY   ++A+
Sbjct: 24820 YLAWNPPLQDGGANISHYIIEKRETSRLSWTQVSTEVQALNYKVTKLLPGNEYIFRVMAV 24879

Query: 1070  -KGNQESPKATGVFTTLQP----GSSIPPYNTEVTETTIVITWTP------APRIGFKLG 1118
              K     P  +G  T   P    G    P  + +T+ ++V+TW            G+ L 
Sbjct: 24880 NKYGIGEPLESGPVTACNPYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILE 24939

Query: 1119  VRPSQGGEAPR--EVTSDSGSIVVSGLTPGVEYVYTIQVLRD---GQERDAPIVNKVVTP 1173
              R  +G    +  + T     + V+GLT G  Y + +        G+  +  +  +    
Sbjct: 24940 KRDKEGVRWTKCNKKTLTDLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRACDA 24999

Query: 1174  LSPPTNLHLEANPDTGVLTVS--WERSTTPD---ITGYRI-----------TTTPTNGQQ 1217
             L PP         DT   +VS  W +        + GY +           T TP  G Q
Sbjct: 25000 LYPPGPPSNPKVTDTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAADEWTTCTPPTGLQ 25059

Query: 1218  GNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDD----KESVPISDTIIPAVPPP--- 1270
             G              T   L    EYN  +  +  +      ++P S      + PP   
Sbjct: 25060 GKQF-----------TVTKLKENTEYNFRICAINSEGVGEPATLPGSVVAQERIEPPEIE 25108

Query: 1271  --TDLRFTNI--GPDTMR----VTWAPPPSIDLTNFLVRYSPVKNE-EDVAELSISPSDN 1321
                DLR   +     T+R    +   P P        V++   +    D A++ ++ S  
Sbjct: 25109 LDADLRKVVVLRASATLRLFVTIKGRPEPE-------VKWEKAEGILTDRAQIEVTSSFT 25161

Query: 1322  AVVLTNLLPGTEYVVSVSSVYEQHESTP-LRGRQKTGLDSPTGIDFSDITANSFTVHWIA 1380
              +V+ N+        +++        T  +  R      +P  +   ++  +S T+ W  
Sbjct: 25162 MLVIDNVTRFDSGRYNLTLENNSGSKTAFVNVRVLDSPSAPVNLTIREVKKDSVTLSWEP 25221

Query: 1381  PR----ATITGYRIRHHPEHFSGRPREDRVPHS--RNSITLTNLTPGTEYVVSIVALNGR 1434
             P     A IT Y +       + R     + ++  + +  + NL  G  Y   ++A N  
Sbjct: 25222 PLIDGGAKITNYIVEKRE---TTRKAYATITNNCTKTTFRIENLQEGCSYYFRVLASNEY 25278

Query: 1435  EES-PLLIGQQSTVSDVPRD---LEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSP 1490
                 P    +   VS+ P     + +V  T  +  I W+ P            E+ G S 
Sbjct: 25279 GIGLPAETTEPVKVSEPPLPPGRVTLVDVTRNTATIKWEKP------------ESDGGSK 25326

Query: 1491  VQEFTVP----GSKS----------TATISGLKPGVDYTITVYAVTGRGDSPASSKPISI 1536
             +  + V     GS+            ATISGL  G +Y   V AV  +G S      + +
Sbjct: 25327 ITGYVVEMQTKGSEKWSTCTQVKTLEATISGLTAGEEYVFRVAAVNEKGRSDPRQLGVPV 25386

Query: 1537  NYRTEIDKPSQMQVTDVQDNSISVK---WLPSSSPVTGYRVTTTPKNGPGPTKTKT---- 1589
               R    KPS     ++  ++ +VK    L    P  G    T      G T  +T    
Sbjct: 25387 IARDIEIKPS----VELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVN 25442

Query: 1590  --AGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKG-LAFTDVDVD 1646
               +    T ++I+           +   N +G     +   V +   P G +   +V  D
Sbjct: 25443 VSSSKTVTSLSIKEASKEDVGTYELCVSNSAGSITVPITIIVLDRPGPPGPIRIDEVSCD 25502

Query: 1647  SIKIAWESPQ----GQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSV 1702
             SI I+W  P+     Q+S Y V           +  +      + ++  L  GSEY   V
Sbjct: 25503 SITISWNPPEYDGGCQISNYIVEKKETTSTTWHIV-SQAVARTSIKIVRLTTGSEYQFRV 25561

Query: 1703  VALH-----DDMESQPLIGTQSTAIPAPTDL-KFTQVTPTSLSAQWTPP----NVQLTGY 1752
              A +        ES  ++     + P P    K    T +++   W  P      ++ GY
Sbjct: 25562 CAENRYGKSSYSESSAVVAEYPFSPPGPPGTPKVVHATKSTMLVTWQVPVNDGGSRVIGY 25621

Query: 1753  RVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGV--VTT 1810
              +    +      K   +    + + VSGL     YE  VYA       + ++    V  
Sbjct: 25622 HLEYKERSSILWSKANKILIADTQMKVSGLDEGLMYEYRVYAENIAGIGKCSKSCEPVPA 25681

Query: 1811  LENVSPPRRARVTDATETTITISW 1834
              +   PP +  VT+ T  ++++ W
Sbjct: 25682 RDPCDPPGQPEVTNITRKSVSLKW 25705



 Score = 92.0 bits (227), Expect = 6e-18
 Identities = 265/1345 (19%), Positives = 470/1345 (34%), Gaps = 186/1345 (13%)

Query: 814   PPDPTVD--QVDDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTL 867
             PP P  D   +D  +  + W  P     + IT Y +       G         T  S  +
Sbjct: 18994 PPQPPFDISDIDADACSLSWHIPLEDGGSNITNYIVEKCDVSRGDWVTALASVTKTSCRV 19053

Query: 868   SDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPS-PRDLQFVEVTDVKVTIM 926
               L PG +Y   + A      S P+   +     P    VPS P++ +  +V    + + 
Sbjct: 19054 GKLIPGQEYIFRVRAENRFGISEPLTSPKMVAQFPFG--VPSEPKNARVTKVNKDCIFVA 19111

Query: 927   WTPPES----AVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSH 982
             W  P+S     + GY ++    N          + R+T     GL  G+ Y F+++A++ 
Sbjct: 19112 WDRPDSDGGSPIIGYLIERKERNSLLWVKANDTLVRSTEYPCAGLVEGLEYSFRIYALNK 19171

Query: 983   GRESKPL--TAQQTTKL--DAPTNLQFVNETDSTVLVRWTPPR----AQITGYRLTVGLT 1034
                S P   T   T ++  D P   + ++ T STV + W  P+    ++I GY +     
Sbjct: 19172 AGSSPPSKPTEYVTARMPVDPPGKPEVIDVTKSTVSLIWARPKHDGGSKIIGYFVEACKL 19231

Query: 1035  RRGQPRQYNVGPSV---SKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSI 1091
                +  + N  P      +Y    L+  ++Y    +A      SP +           ++
Sbjct: 19232 PGDKWVRCNTAPHQIPQEEYTATGLEEKAQYQFRAIARTAVNISPPSEPSDPVTILAENV 19291

Query: 1092  PP----------YNTEVTETTIVITWT----PAPRIGFKLG---VRPSQGGEAPREVTSD 1134
             PP            T    T + +  T    P P + +K     ++P++G +   +   +
Sbjct: 19292 PPRIDLSVAMKSLLTVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQ--RN 19349

Query: 1135  SGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVS 1194
               ++ +  +       YTI        + A I  KV+    PP ++ +        + +S
Sbjct: 19350 LCTLELFSVNRKDSGDYTITAENSSGSKSATIKLKVLDKPGPPASVKINKMYSDRAM-LS 19408

Query: 1195  WE---RSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVK 1251
             WE        +IT Y +    T+      +   V    +SC+ + L  G EY   +    
Sbjct: 19409 WEPPLEDGGSEITNYIVDKRETSRPNWAQVSATVPI--TSCSVEKLIEGHEYQFRICAEN 19466

Query: 1252  DDKESVPI-SDTIIPAVP--------PPTDLRFTNIGPDTMRVTWAPPPS---IDLTNFL 1299
                   P+ ++  I   P        PP     +NI  D M V+W PP       +T +L
Sbjct: 19467 KYGVGDPVFTEPAIAKNPYDPPGRCDPPV---ISNITKDHMTVSWKPPADDGGSPITGYL 19523

Query: 1300  V--RYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTG 1357
             +  R +   N   V    I   +  +  T L  GTEY   V+++ +     P    +   
Sbjct: 19524 LEKRETQAVNWTKVNRKPII--ERTLKATGLQEGTEYEFRVTAINKAGPGKPSDASKAAY 19581

Query: 1358  LDSP-------TGIDFSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPREDRV 1406
                P             D T +S ++ W  P     + I GY +           R +  
Sbjct: 19582 ARDPQYPPGPPAFPKVYDTTRSSVSLSWGKPAYDGGSPIIGYLVEVKRADSDNWVRCNLP 19641

Query: 1407  PH-SRNSITLTNLTPGTEYVVSIVALNGREES-PLLIGQQSTVSDV--PRDLEVVAATPT 1462
              +  +    +T L   T+Y   + A+N    S P  +  +    D+  P + E+ A    
Sbjct: 19642 QNLQKTRFEVTGLMEDTQYQFRVYAVNKIGYSDPSDVPDKHYPKDILIPPEGELDADLRK 19701

Query: 1463  SLLISWDAPAVTVRYY---------RITYGETGGNSPVQEFTVPGSKSTATISGLKPGVD 1513
             +L++      VT+R Y         +IT+ +   N   +      S    T    +    
Sbjct: 19702 TLILR---AGVTMRLYVPVKGRPPPKITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNK 19758

Query: 1514  YTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLP----SSSPV 1569
             Y    Y +T           I +        P  + V ++  +S  V W P      SP+
Sbjct: 19759 YDAGKYILTLENSCGKKEYTIVVKVLDTPGPPVNVTVKEISKDSAYVTWEPPIIDGGSPI 19818

Query: 1570  TGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAV 1629
               Y V            T T    +T   +  L+    Y   V+A+N  G   P      
Sbjct: 19819 INYVVQKRDAERKS-WSTVTTECSKTSFRVANLEEGKSYFFRVFAENEYGIGDPGETRDA 19877

Query: 1630  TNIDRPKG----LAFTDVDVDSIKIAWESPQG----QVSRYRVTYSSPEDGIHELFPAPD 1681
                 +  G    L    V   S  I W+ P      ++  Y V + + E+    +  +  
Sbjct: 19878 VKASQTPGPVVDLKVRSVSKSSCSIGWKKPHSDGGSRIIGYVVDFLTEENKWQRVMKSLS 19937

Query: 1682  GEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQ 1741
              +    +L     G EYT  V A +++ E  P        + A  D     V    L  +
Sbjct: 19938 LQYSAKDLT---EGKEYTFRVSAENENGEGTP----SEITVVARDD-----VVAPDLDLK 19985

Query: 1742  WTPPNVQL----TGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKD 1797
               P    L    + +R+++  K K  P        D        L   T+  V   A+  
Sbjct: 19986 GLPDLCYLAKENSNFRLKIPIKGKPAPSVSWKKGEDP-------LATDTRVSVESSAVNT 20038

Query: 1798  TLTSRPAQ----GVVT-TLENVSPPRRARVT-----------------DATETTITISWR 1835
             TL     Q    G  T TL+NV+  +   ++                 + T   +T+ W 
Sbjct: 20039 TLIVYDCQKSDAGKYTITLKNVAGTKEGTISIKVVGKPGIPTGPIKFDEVTAEAMTLKWA 20098

Query: 1836  TKTET----ITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYL-----YTL 1886
                +     IT + ++   +     +         ++ +T L  G +Y   +     Y +
Sbjct: 20099 PPKDDGGSEITNYILEKRDSVNNKWVTCASAVQKTTFRVTRLHEGMEYTFRVSAENKYGV 20158

Query: 1887  NDNARSSPVVIDASTAI-DAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPG 1941
              +  +S P+V      + DAP     +    +S+ ++W  P+    + ITGY +++++  
Sbjct: 20159 GEGLKSEPIVARHPFDVPDAPPPPNIVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKERN 20218

Query: 1942  SPPREVVPRPRPGVTEATITGLEPGTEYTIYVIAL------KNNQKSEPLI--------G 1987
             S   +   +    + +  +TGL  G EY   V+A+      K +  SEP++        G
Sbjct: 20219 SLLWKRANKTPIRMRDFKVTGLTEGLEYEFRVMAINLAGVGKPSLPSEPVVALDPIDPPG 20278

Query: 1988  RKKTV-----QKTPFVTHPGYDTGN 2007
             + + +       T   T P YD G+
Sbjct: 20279 KPEVINITRNSVTLIWTEPKYDGGH 20303



 Score = 91.7 bits (226), Expect = 8e-18
 Identities = 294/1501 (19%), Positives = 530/1501 (35%), Gaps = 198/1501 (13%)

Query: 628   IQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISI 684
             + W  P     S I+ Y+L  R   +V   K    P    +    GL+ G  YE ++ +I
Sbjct: 19506 VSWKPPADDGGSPITGYLLEKRETQAVNWTKVNRKPIIERTLKATGLQEGTEYEFRVTAI 19565

Query: 685   QQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSW---- 740
              + G  + +              S         + P       V + T SS  +SW    
Sbjct: 19566 NKAGPGKPSD------------ASKAAYARDPQYPPGPPAFPKVYDTTRSSVSLSWGKPA 19613

Query: 741   VSASDTVSGFRVEYELSEEGDEPQYLDLPST--ATSVNIPDLLPGRKYIVNVYQISEDGE 798
                   + G+ VE + + + D     +LP     T   +  L+   +Y   VY +++ G 
Sbjct: 19614 YDGGSPIIGYLVEVKRA-DSDNWVRCNLPQNLQKTRFEVTGLMEDTQYQFRVYAVNKIG- 19671

Query: 799   QSLILSTSQTTAPD--------APPDPTVDQVDDTSIVVR---WSRPQAPITGYRIVYSP 847
                   +  +  PD         PP+  +D     ++++R     R   P+ G      P
Sbjct: 19672 -----YSDPSDVPDKHYPKDILIPPEGELDADLRKTLILRAGVTMRLYVPVKGRP---PP 19723

Query: 848   SVEGSSTELNLPETAN-SVTLSDLQPGV-----------QYNITIYAVEENQESTPVVIQ 895
              +  S   +NL +     +  +D    +           +Y +T+      +E T VV  
Sbjct: 19724 KITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKYILTLENSCGKKEYTIVVKV 19783

Query: 896   QETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPGEHG 951
              +T G P + TV         E++     + W PP     S +  Y V            
Sbjct: 19784 LDTPGPPVNVTVK--------EISKDSAYVTWEPPIIDGGSPIINYVVQKRDAERKSWST 19835

Query: 952   QRLPISRNTFAEVTGLSPGVTYYFKVFAVSH---GRESKPLTAQQTTKLDAP-TNLQFVN 1007
                  S+ +F  V  L  G +Y+F+VFA +    G   +   A + ++   P  +L+  +
Sbjct: 19836 VTTECSKTSF-RVANLEEGKSYFFRVFAENEYGIGDPGETRDAVKASQTPGPVVDLKVRS 19894

Query: 1008  ETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYT 1063
              + S+  + W  P     ++I GY +   LT   + ++     S+ +Y  ++L    EYT
Sbjct: 19895 VSKSSCSIGWKKPHSDGGSRIIGYVVDF-LTEENKWQRVMKSLSL-QYSAKDLTEGKEYT 19952

Query: 1064  VSLVAIKGNQE-SPKATGVFT---TLQPG---SSIPPYNTEVTETT-----IVITWTPAP 1111
               + A   N E +P    V      + P      +P       E +     I I   PAP
Sbjct: 19953 FRVSAENENGEGTPSEITVVARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPIKGKPAP 20012

Query: 1112  RIGFKLGVRP-SQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKV 1170
              + +K G  P +       E ++ + +++V          YTI +      ++  I  KV
Sbjct: 20013 SVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKEGTISIKV 20072

Query: 1171  VTPLSPPTNLHLEANPDTGVLTVSW---ERSTTPDITGYRITTTPTNGQQGNSLEEVVHA 1227
             V     PT            +T+ W   +     +IT Y +    +   +  +    V  
Sbjct: 20073 VGKPGIPTGPIKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDSVNNKWVTCASAV-- 20130

Query: 1228  DQSSCTFDNLSPGLEYNVSV-----YTVKDDKESVPI---SDTIIPAVPPPTDLRFTNIG 1279
              +++     L  G+EY   V     Y V +  +S PI       +P  PPP ++   ++ 
Sbjct: 20131 QKTTFRVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVPDAPPPPNI--VDVR 20188

Query: 1280  PDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVA-----ELSISPSDNAVVLTNLLPGTEY 1334
              D++ +TW  P     +     +   K    +      +  I   D  V  T L  G EY
Sbjct: 20189 HDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTPIRMRDFKV--TGLTEGLEY 20246

Query: 1335  VVSVSSVYEQHESTPLRGRQKT----GLDSPTGIDFSDITANSFTVHWIAPR----ATIT 1386
                V ++       P    +       +D P   +  +IT NS T+ W  P+      +T
Sbjct: 20247 EFRVMAINLAGVGKPSLPSEPVVALDPIDPPGKPEVINITRNSVTLIWTEPKYDGGHKLT 20306

Query: 1387  GYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN--GREESPLLIGQQ 1444
             GY +           + + V     + T+T+L  G +Y   I A N  G   +P     +
Sbjct: 20307 GYIVEKRDLPSKSWMKANHVNVPECAFTVTDLVEGGKYEFRIRAKNTAGAISAP----SE 20362

Query: 1445  STVSDVPRDLEVVAATPTSLLISWDAPAVTVR----------------YYRITYGETGGN 1488
             ST + + +D       PT +L       +T++                  + ++ + G +
Sbjct: 20363 STETIICKD---EYEAPTIVLDPTIKDGLTIKAGDTIVLNAISILGKPLPKSSWSKAGKD 20419

Query: 1489  SPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQM 1548
                 + T   S  T+++  +K         Y +T         + + +        P  +
Sbjct: 20420 IRPSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFGTKVEHVKVTVLDVPGPPGPV 20479

Query: 1549  QVTDVQDNSISVKWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQP 1604
             ++++V     ++ W P      SP+  Y +     +    T           +  + +Q 
Sbjct: 20480 EISNVSAEKATLTWTPPLEDGGSPIKSYILEKRETSRLLWTVVSEDIQSCRHVATKLIQG 20539

Query: 1605  TVEYVVSVYAQNPSGESQPLVQTAVTNIDR------PKGLAFTDVDVDSIKIAWESP--- 1655
               EY+  V A N  G+ +P+    V  +DR      P+    ++V  ++  ++W+ P   
Sbjct: 20540 N-EYIFRVSAVNHYGKGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSWKRPVDD 20598

Query: 1656  -QGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVA-----LHDDM 1709
                +++ Y V     +             +   ++ GL+ GS Y   V A     +    
Sbjct: 20599 GGSEITGYHVERREKKSLRWVRAIKTPVSDLRCKVTGLQEGSTYEFRVSAENRAGIGPPS 20658

Query: 1710  ESQPLIGTQSTAIP--APTDLKFTQVTPTSLSAQWTPPN----VQLTGYRVRVTPKEKTG 1763
             E+   +  +  A P   P++   T  T  S S  W  P+    +++TGY   V   +K G
Sbjct: 20659 EASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLAWGKPHYDGGLEITGY---VVEHQKVG 20715

Query: 1764  PMKEI----NLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRR 1819
                 I      A   +  VV  L    KY   + A+ D     PA  V+  +E V     
Sbjct: 20716 DEAWIKDTTGTALRITQFVVPDLQTKEKYNFRISAINDAGVGEPA--VIPDVEIVEREMA 20773

Query: 1820  ARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIK-------PDVRSYTITG 1872
                    E   T+  R          +   PA   T  +  I         +  S+T+  
Sbjct: 20774 PDFELDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKNRANIENTESFTLLI 20833

Query: 1873  LQPGTDYKI--YLYTLNDNARSSPVVIDASTAIDAPS---NLRFLATTPNSLLVSWQPP- 1926
             +     Y    ++ T+ + A      ++    +D P    NLR    T +S+ + W  P 
Sbjct: 20834 IPECNRYDTGKFVMTIENPAGKKSGFVNV-RVLDTPGPVLNLRPTDITKDSVTLHWDLPL 20892

Query: 1927  ---RARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSE 1983
                 +RIT YI++ ++  +         +       +TGL  G EY   V+A       E
Sbjct: 20893 IDGGSRITNYIVE-KREATRKSYSTATTKCHKCTYKVTGLSEGCEYFFRVMAENEYGIGE 20951

Query: 1984  P 1984
             P
Sbjct: 20952 P 20952



 Score = 90.9 bits (224), Expect = 1e-17
 Identities = 273/1318 (20%), Positives = 459/1318 (34%), Gaps = 189/1318 (14%)

Query: 771   TATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPP---DPTVDQVDDTSI 827
             ++TS  + DL     +   V   +E G      +T    A + P    D ++     TS+
Sbjct: 27420 SSTSFKLIDLSEKTPFFFRVLAENEIGIGEPCETTEPVKAAEVPAPIRDLSMKDSTKTSV 27479

Query: 828   VVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAV 883
             ++ W++P     + IT Y +      E + +   + +T   + +S L+        ++A 
Sbjct: 27480 ILSWTKPDFDGGSVITEYVVERKGKGEQTWSHAGISKTCE-IEVSQLKEQSVLEFRVFAK 27538

Query: 884   EENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIP 943
              E   S PV I   T      + + +P ++   ++   +VT+           Y+    P
Sbjct: 27539 NEKGLSDPVTIGPITV----KELIITP-EVDLSDIPGAQVTVRIGHNVHLELPYKGKPKP 27593

Query: 944   VNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTN- 1002
                  + G  LP+  + F   +     +T   K     HG +   +      ++  P   
Sbjct: 27594 SISWLKDG--LPLKESEFVRFSKTENKITLSIKNAKKEHGGKYTVILDNAVCRIAVPITV 27651

Query: 1003  ------------LQFVNETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGP 1046
                         ++F      +V++ W  P      +IT Y +    T +   +      
Sbjct: 27652 ITLGPPSKPKGPIRFDEIKADSVILSWDVPEDNGGGEITCYSIEKRETSQTNWKMVCSSV 27711

Query: 1047  SVSKYPLRNLQPASEYTVSLVAI-KGNQESPKATGVFTTLQ----PGSSIPPYNTEVTET 1101
             + + + + NL   +EY   + A  +     P  + +         PG    P    VT  
Sbjct: 27712 ARTTFKVPNLVKDAEYQFRVRAENRYGVSQPLVSSIIVAKHQFRIPGPPGKPVIYNVTSD 27771

Query: 1102  TIVITWTP------APRIGFKLGVRPSQGGEAPREVTSD-SG-SIVVSGLTPGVEYVYTI 1153
              + +TW        +   GF +  +        +  TS  SG     +GL  G++Y + +
Sbjct: 27772 GMSLTWDAPVYDGGSEVTGFHVEKKERNSILWQKVNTSPISGREYRATGLVEGLDYQFRV 27831

Query: 1154  QVLRDG---QERDAPIVNKVVTPLSPP-TNLHLEANPDTGVLTVSWE---RSTTPDITGY 1206
                         D       V+P+ PP T  +++   +T  +T+ W    R     I GY
Sbjct: 27832 YAENSAGLSSPSDPSKFTLAVSPVDPPGTPDYIDVTRET--ITLKWNPPLRDGGSKIVGY 27889

Query: 1207  RITTTPTNGQQGNSL-EEVVHADQSSC--TFDNLSPGLEYNV------SVYTVKDDKESV 1257
              I       +QGN         D S C  T   LSPG  Y        +V T+    +S 
Sbjct: 27890 SIEK-----RQGNERWVRCNFTDVSECQYTVTGLSPGDRYEFRIIARNAVGTISPPSQSS 27944

Query: 1258  PISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNE---EDVAEL 1314
              I  T    VPP         GP+                 LV+  PV      +D  E+
Sbjct: 27945 GIIMTRDENVPP-----IVEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVTWFKDGVEI 27999

Query: 1315  SISPSDNAVVLTNLLPGTEYVV--------SVSSVYEQHESTPLRGRQKTGLDSPTG--- 1363
                 +   + +T++L  T   V         V +V  ++ S   +   K  +    G   
Sbjct: 28000 EKRMN---MEITDVLGSTSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQDTPGKVV 28056

Query: 1364  --IDFSDITANSFTVHWIAPR----ATITGYRI-RHHPEHFSGRPREDRVPHSRNSITLT 1416
               I F++IT    T+ W AP     A IT Y I +      +    ED+      S T  
Sbjct: 28057 GPIRFTNITGEKMTLWWDAPLNDGCAPITHYIIEKRETSRLAWALIEDKC--EAQSYTAI 28114

Query: 1417  NLTPGTEYVVSIVALN----GR--EESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDA 1470
              L  G EY   + A+N    GR  +  P++   Q TV D P   E    T  S+ ++W  
Sbjct: 28115 KLINGNEYQFRVSAVNKFGVGRPLDSDPVVAQIQYTVPDAPGIPEPSNITGNSITLTWAR 28174

Query: 1471  PAVTVRYYRITYGETGGNSPVQEFTV-----------------PGSKSTATISGLKPGVD 1513
             P            E+ G S +Q++ +                 P S++   ++GL  G +
Sbjct: 28175 P------------ESDGGSEIQQYILERREKKSTRWVKVISKRPISETRFKVTGLTEGNE 28222

Query: 1514  YTITVYAVTGRGDSPASSKPISINYRTEIDKPSQ---MQVTDVQDNSISVKW----LPSS 1566
             Y   V A    G  PAS     I  R  ++ P     ++VTD    ++S++W        
Sbjct: 28223 YEFHVMAENAAGVGPASGISRLIKCREPVNPPGPPTVVKVTDTSKTTVSLEWSKPVFDGG 28282

Query: 1567  SPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQ 1626
               + GY +     +     K       +T  T+  LQ   EY   V A N +G+      
Sbjct: 28283 MEIIGYIIEMCKADLGDWHKVNAEACVKTRYTVTDLQAGEEYKFRVSAINGAGKGDSCEV 28342

Query: 1627  TA-VTNIDRPKGLAFTDVDVDS-IKIAWESPQGQVSRYRVTY----------SSPEDGIH 1674
             T  +  +DR   L   ++D+D+  K       G   R  + Y          S P+  + 
Sbjct: 28343 TGTIKAVDR---LTAPELDIDANFKQTHVVRAGASIRLFIAYQGRPTPTAVWSKPDSNLS 28399

Query: 1675  ---ELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFT 1731
                ++         T E        +YT++V            +    T  P P  + F 
Sbjct: 28400 LRADIHTTDSFSTLTVENCNRNDAGKYTLTVENNSGSKSITFTVKVLDTPGP-PGPITFK 28458

Query: 1732  QVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKE----INLAPDSSSVVVSGLMVATK 1787
              VT  S +  W  P +   G R+     EK    +     I+         V+ L     
Sbjct: 28459 DVTRGSATLMWDAPLLD-GGARIHHYVVEKREASRRSWQVISEKCTRQIFKVNDLAEGVP 28517

Query: 1788  YEVSVYALKDTLTSRPAQ--GVVTTLENVSPPRRARVTDATETTITISW----RTKTETI 1841
             Y   V A+ +     P +    +   E  +PPRR  V D ++++  ++W          I
Sbjct: 28518 YYFRVSAVNEYGVGEPYEMPEPIVATEQPAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRI 28577

Query: 1842  TGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDAST 1901
             TG+ ++         ++      + ++T+  L   T+Y+  +   ND   S P    +S 
Sbjct: 28578 TGYLLEMRQKGSDFWVEAGHTKQL-TFTVERLVEKTEYEFRVKAKNDAGYSEPREAFSSV 28636

Query: 1902  AIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVP---RPRPGVT 1956
              I  P         P + L         IT  +I   K GSP    VP   RP P VT
Sbjct: 28637 IIKEPQ------IEPTADLTG-------ITNQLITC-KAGSPFTIDVPISGRPAPKVT 28680



 Score = 89.7 bits (221), Expect = 3e-17
 Identities = 260/1286 (20%), Positives = 475/1286 (36%), Gaps = 231/1286 (17%)

Query: 780   LLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPIT 839
             ++P ++Y++ V  ++  G       +    A D    PT+D      IV+   +   P+ 
Sbjct: 14350 VVPDKEYVLRVRAVNAIGVSEPSEISENVVAKDPDCKPTIDLETHDIIVIEGEKLSIPVP 14409

Query: 840   GYRIVYSPSV----EGSSTELNLPETANSVTLS---DLQPGVQYNITIYAV--EENQEST 890
              +R V  P+V    +G   + +   T  +  +S   ++   V+ +  IY +  E    S 
Sbjct: 14410 -FRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSA 14468

Query: 891   PVVIQQETTGTPRSDTVPSP-RDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGE 949
                I  +  G      +P P +D++  ++T     + W PPE    G    +  V    E
Sbjct: 14469 TASINVKVIG------LPGPCKDIKASDITKSSCKLTWEPPE--FDGGTPILHYVLERRE 14520

Query: 950   HGQR--LPI--SRNTFA-EVTGLSPGVTYYFKVFAVSH--GRE----SKPLTAQQTTKL- 997
              G+R  +P+    N  +  V  L P   Y+F+V AV+   G E      P+ AQ   +  
Sbjct: 14521 AGRRTYIPVMSGENKLSWTVKDLIPNGEYFFRVKAVNKVGGGEYIELKNPVIAQDPKQPP 14580

Query: 998   DAPTNLQFVNETDSTVLVRWTPPR----AQITGY---RLTVGLTRRGQPRQYNVGPSVSK 1050
             D P +++  N T   + + W PP     ++I GY   ++  G  R  +  ++ V   +  
Sbjct: 14581 DPPVDVEVHNPTAEAMTITWKPPLYDGGSKIMGYIIEKIAKGEERWKRCNEHLV--PILT 14638

Query: 1051  YPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPA 1110
             Y  + L+   EY   + A         A G+    +P  + PP        T  +    A
Sbjct: 14639 YTAKGLEEGKEYQFRVRA-------ENAAGIS---EPSRATPP--------TKAVDPIDA 14680

Query: 1111  PRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVL--RDGQERDAPIVN 1168
             P++  +  +   +G E   +  S SGS       P + ++    V+   + ++R AP+V 
Sbjct: 14681 PKVILRTSLEVKRGDEIALDA-SISGSPY-----PTITWIKDENVIVPEEIKKRAAPLVR 14734

Query: 1169  KVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHAD 1228
             +    +       L   P T  L++                    N ++G S   V    
Sbjct: 14735 RRKGEVQEEEPFVL---PLTQRLSID-------------------NSKKGESQLRVR--- 14769

Query: 1229  QSSCTFDNLSPGLEYNVSVYTVKDDK--ESVPISDTIIPAVPPPTDLRFTNIGPDTMRVT 1286
                   D+L P  ++ + +  V++D      P + +++    PP +  F +I   ++   
Sbjct: 14770 ------DSLRP--DHGLYMIKVENDHGIAKAPCTVSVLDTPGPPINFVFEDIRKTSVLCK 14821

Query: 1287  WAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHE 1346
             W PP   D  + ++ Y+  K ++        P    +V+T+ L   +Y  SV+ + E  E
Sbjct: 14822 WEPPLD-DGGSEIINYTLEKKDKT------KPDSEWIVVTSTLRHCKY--SVTKLIEGKE 14872

Query: 1347  ------------------STPLRGRQKTGL-DSPTGIDFSDITANSFTVHWIAPR---AT 1384
                               S PL  +   G  D+P      D+T+NS  V W  P+   + 
Sbjct: 14873 YLFRVRAENRFGPGPPCVSKPLVAKDPFGPPDAPDKPIVEDVTSNSMLVKWNEPKDNGSP 14932

Query: 1385  ITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN----GREESPLL 1440
             I GY +     + +   R ++   +     +  L  G  YV  + A N    G+   P  
Sbjct: 14933 ILGYWLEKREVNSTHWSRVNKSLLNALKANVDGLLEGLTYVFRVCAENAAGPGKFSPP-- 14990

Query: 1441  IGQQSTVSD--------VPRDLEVVAATPTSLLISWDAPAVT----VRYYRITYGETGGN 1488
                  T  D        +PR   V   + T++ + W+ PA      +  Y +     G N
Sbjct: 14991 -SDPKTAHDPISPPGPPIPR---VTDTSSTTIELEWEPPAFNGGGEIVGYFVDKQLVGTN 15046

Query: 1489  SPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDS-PASSKPISINYRTEIDKPSQ 1547
                +           T+  ++ G DY + V AV   G+  P  ++P+++    E  +P  
Sbjct: 15047 EWSRCTEKMIKVRQYTVKEIREGADYKLRVSAVNAAGEGPPGETQPVTV---AEPQEPPA 15103

Query: 1548  MQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTK--TKTAGP-DQTEMTIEGLQP 1604
             +++       +SVK           R+       P PTK  TK  G  D+  + I+ +  
Sbjct: 15104 VEL------DVSVKGGIQIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKDRVVIDNVGT 15157

Query: 1605  TVEYVVS-----------VYAQNPSGESQPLVQTAVTNIDRP-KGLAFTDVDVDSIKIAW 1652
               E ++            + A N  G      +  V ++  P   L     +     + W
Sbjct: 15158 KSELIIKDALRKDHGRYVITATNSCGSKFAAARVEVFDVPGPVLDLKPVVTNRKMCLLNW 15217

Query: 1653  ESPQ----GQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALH-- 1706
               P+     +++ + +     +  +H      + E    ++ GL  G EY   V+A +  
Sbjct: 15218 SDPEDDGGSEITGFIIERKDAK--MHTWRQPIETERSKCDITGLLEGQEYKFRVIAKNKF 15275

Query: 1707  ---DDMESQPLIGTQSTAIP-APTDLKFTQVTPTSLSAQWTPPNVQ----LTGYRVRVTP 1758
                  +E  P++       P +P  L +T+ T ++++  W  P       + GY +    
Sbjct: 15276 GCGPPVEIGPILAVDPLGPPTSPERLTYTERTKSTITLDWKEPRSNGGSPIQGYIIEKRR 15335

Query: 1759  KEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPA--QGVVTTLENVSP 1816
              +K    +       ++S +V  L     YE  V A+ +   S P+    VV   + V P
Sbjct: 15336 HDKPDFERVNKRLCPTTSFLVENLDEHQMYEFRVKAVNEIGESEPSLPLNVVIQDDEVPP 15395

Query: 1817  PRRARVTDATETTIT-------------------ISWRTKTETITGFQVDAVPANGQTPI 1857
               + R++   +T                      I W +K ET+     DA+    +   
Sbjct: 15396 TIKLRLSVRGDTIKVKAGEPVHIPADVTGLPMPKIEW-SKNETVIEKPTDALQITKEEVS 15454

Query: 1858  QRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAI-DAPSNLRFLATT- 1915
             +   K ++          GT      YT+  + R   V  +    + D PS  R LA T 
Sbjct: 15455 RSEAKTELSIPKAVREDKGT------YTVTASNRLGSVFRNVHVEVYDRPSPPRNLAVTD 15508

Query: 1916  --PNSLLVSWQPP----RARITGYII 1935
                 S  ++W  P     + IT Y+I
Sbjct: 15509 IKAESCYLTWDAPLDNGGSEITHYVI 15534



 Score = 89.7 bits (221), Expect = 3e-17
 Identities = 320/1572 (20%), Positives = 568/1572 (36%), Gaps = 254/1572 (16%)

Query: 611   PVEVFITETPSQP----------NSHPIQWNAPQP---SHISKYILRWRPKNSVGRWKEA 657
             P  +  TE P+ P          +S  + W  P     S I+ Y+L  R K S   W EA
Sbjct: 28537 PEPIVATEQPAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGS-DFWVEA 28595

Query: 658   TIPGHLN--SYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNT--VTG 713
                GH    ++T++ L     YE ++ +    G+ E  R  F++     P    T  +TG
Sbjct: 28596 ---GHTKQLTFTVERLVEKTEYEFRVKAKNDAGYSE-PREAFSSVIIKEPQIEPTADLTG 28651

Query: 714   ETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTAT 773
              T       A S    ++  S      V+       +++E    +E D    +      T
Sbjct: 28652 ITNQLITCKAGSPFTIDVPISGRPAPKVT-------WKLEEMRLKETDRVS-ITTTKDRT 28703

Query: 774   SVNIPDLLPGR--KYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPT-VDQVDDTSIVVR 830
             ++ + D + G   +Y + +   +  G ++  ++      P     P  V  V   S V+ 
Sbjct: 28704 TLTVKDSMRGDSGRYFLTLENTA--GVKTFSVTVVVIGRPGPVTGPIEVSSVSAESCVLS 28761

Query: 831   WSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITI-----Y 881
             W  P+      IT Y +    S   +   +N       + ++ L   ++Y+  +     +
Sbjct: 28762 WGEPKDGGGTEITNYIVEKRESGTTAWQLVNSSVKRTQIKVTHLTKYMEYSFRVSSENRF 28821

Query: 882   AVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGY 937
              V +  ES P++ +      P + T P     +   V+   ++I W  P     S + GY
Sbjct: 28822 GVSKPLESAPIIAEHPFV-PPSAPTRP-----EVYHVSANAMSIRWEEPYHDGGSKIIGY 28875

Query: 938   RVDVIPVN-LPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFA-----VSHGRE-SKPLT 990
              V+    N +      ++P     + +VTGL  G+ Y F+ +A     VS   E S+P+ 
Sbjct: 28876 WVEKKERNTILWVKENKVPCLECNY-KVTGLVEGLEYQFRTYALNAAGVSKASEASRPIM 28934

Query: 991   AQQTTKLDAPTNLQFVNETDSTVLVRWTPPR----AQITGYRL----------------- 1029
             AQ    +DAP   +  + T STV + W+ P     +++ GY +                 
Sbjct: 28935 AQ--NPVDAPGRPEVTDVTRSTVSLIWSAPAYDGGSKVVGYIIERKPVSEVGDGRWLKCN 28992

Query: 1030  ---------TVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKAT- 1079
                      TV     G   ++ V   ++K     +   SE T   V  +     PKA  
Sbjct: 28993 YTIVSDNFFTVTALSEGDTYEFRV---LAKNAAGVISKGSEST-GPVTCRDEYAPPKAEL 29048

Query: 1080  -----GVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGE-APREVTS 1133
                  G   T++ GS +             +   P P+I +  G +     E    + T 
Sbjct: 29049 DARLHGDLVTIRAGSDL--------VLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTG 29100

Query: 1134  DSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTV 1193
                + V+          YT+ V      +   ++ KV+    P   L + +       T+
Sbjct: 29101 KRATAVIKFCDRSDSGKYTLTVKNASGTKAVSVMVKVLDSPGPCGKLTV-SRVTQEKCTL 29159

Query: 1194  SWERSTTPDITGYRITTTPTNGQQGNSLEEVV---HADQSSCTFDNLSPGLEYNVSVYTV 1250
             +W  S   +  G  IT      ++ + L  V+        S     L    EY   V  V
Sbjct: 29160 AW--SLPQEDGGAEITHYIVERRETSRLNWVIVEGECPTLSYVVTRLIKNNEYIFRVRAV 29217

Query: 1251  KDDKESVPISDTIIPA-----VP-PPTDLRFTNIGPDTMRVTWAPPPS---IDLTNFLV- 1300
                   VP+    I A     +P PP        G + + + W  P S    +++N+LV 
Sbjct: 29218 NKYGPGVPVESEPIVARNSFTIPSPPGIPEEVGTGKEHIIIQWTKPESDGGNEISNYLVD 29277

Query: 1301  -------RYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGR 1353
                    R++ V  +  V        D  + +T+L+ G +Y   V++V     S P    
Sbjct: 29278 KREKKSLRWTRVNKDYVV-------YDTRLKVTSLMEGCDYQFRVTAVNAAGNSEPSEAS 29330

Query: 1354  QKTGL-------DSPTGIDFSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPR 1402
                           P+     D T +S ++ W  P       I GY +    +      R
Sbjct: 29331 NFISCREPSYTPGPPSAPRVVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDTDQWYR 29390

Query: 1403  EDRVPHSRNS-ITLTNLTPGTEYVVSIVALN--GREESPLLIGQQSTVS--DVPRDLEVV 1457
                    RN+  T+ +L  G +Y   + A+N  G  E    I +   V   ++P DLE+ 
Sbjct: 29391 VHTNATIRNTEFTVPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEIP-DLELA 29449

Query: 1458  AATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTIT 1517
                  ++ I   A        R+    +G   PV  ++  G    A+ + +     Y++ 
Sbjct: 29450 DDLKKTVTIRAGAS------LRLMVSVSGRPPPVITWSKQGI-DLASRAIIDTTESYSLL 29502

Query: 1518  V-----------YAVTGRGDSPASSKPISIN-YRTEIDKPSQMQVTDVQDNSISVKW--- 1562
             +           Y +     S   S  + +  Y T    PS ++V +V  +S+++ W   
Sbjct: 29503 IVDKVNRYDAGKYTIEAENQSGKKSATVLVKVYDTPGPCPS-VKVKEVSRDSVTITWEIP 29561

Query: 1563  -LPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGES 1621
              +   +PV  Y +    +      KT T    +T   I GL     Y   V  +N  G  
Sbjct: 29562 TIDGGAPVNNY-IVEKREAAMRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYGIG 29620

Query: 1622  QPLVQTAVTNIDR----PKGLAFTDVDVDSIKIAWESP----QGQVSRY--RVTYSSPED 1671
             +P   +    +      P  L   DV   ++ +AWE P      +++ Y      +  E 
Sbjct: 29621 EPCETSDAVLVSEVPLVPAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGTER 29680

Query: 1672  GIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFT 1731
              +  +   P   E T  +  L  G +Y   + A ++   S+P    ++       DL+  
Sbjct: 29681 WMKVVTLKPTVLEHT--VTSLNEGEQYLFRIRAQNEKGVSEP---RETVTAVTVQDLR-- 29733

Query: 1732  QVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSG--------LM 1783
              V PT   +      + +   R    P E   P+      P ++S   +G        + 
Sbjct: 29734 -VLPTIDLSTMPQKTIHVPAGR----PVELVIPI--AGRPPPAASWFFAGSKLRESERVT 29786

Query: 1784  VATKYEVSVYALKDTLTSRPAQGVVTTLENVS-----------------PPRRARVTDAT 1826
             V T  +V+   +++T T R        L+NV+                 P    ++ +  
Sbjct: 29787 VETHTKVAKLTIRET-TIRDTGEYTLELKNVTGTTSETIKVIILDKPGPPTGPIKIDEID 29845

Query: 1827  ETTITISWRTKT----ETITGFQVDAVPAN--GQTPIQRTIKPDVRSYTITGLQPGTDYK 1880
              T+ITISW          ++G+ V+   A+  G  P+  ++     ++  T L  G +Y 
Sbjct: 29846 ATSITISWEPPELDGGAPLSGYVVEQRDAHRPGWLPVSESVTRS--TFKFTRLTEGNEYV 29903

Query: 1881  IYLYTLNDNARSSPV---VIDASTAI---DAPSNLRFLATTPNSLLVSWQPPR----ARI 1930
               +   N     S +   VI+  ++I     P  L+    + + + ++W PP     +++
Sbjct: 29904 FRVAATNRFGIGSYLQSEVIECRSSIRIPGPPETLQIFDVSRDGMTLTWYPPEDDGGSQV 29963

Query: 1931  TGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKK 1990
             TGYI++ ++  +     V +    +T    TGL  G EY   V A+      +P    K 
Sbjct: 29964 TGYIVERKEVRADRWVRVNKVPVTMTRYRSTGLTEGLEYEHRVTAINARGSGKPSRPSKP 30023

Query: 1991  TVQKTPFVTHPG 2002
              V   P +  PG
Sbjct: 30024 IVAMDP-IAPPG 30034



 Score = 88.2 bits (217), Expect = 9e-17
 Identities = 339/1547 (21%), Positives = 534/1547 (34%), Gaps = 251/1547 (16%)

Query: 628   IQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISI 684
             + W +P+    S I+ Y++  R  +    W   T      + T++GL  G  Y  ++ + 
Sbjct: 16635 LTWFSPEDDGGSPITNYVIEKRESDRRA-WTPVTYTVTRQNATVQGLIQGKAYFFRIAAE 16693

Query: 685   QQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSAS 744
                G        F  TS +  +        T P  P       V E+T ++  ++W    
Sbjct: 16694 NSIGMGP-----FVETSEALVIREPI----TVPERP---EDLEVKEVTKNTVTLTWNPPK 16741

Query: 745   DTVSGFRVEYELSEE--GDEPQYLDLPSTATS--VNIPDLLPGRKYIVNVYQISEDGEQS 800
                    + Y L     G E  +        S    +  L  G  Y   V  ++  G+  
Sbjct: 16742 YDGGSEIINYVLESRLIGTEKFHKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGK 16801

Query: 801   LILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPE 860
                 T   T  D    PT+       + +R     A    Y     P V     E ++ E
Sbjct: 16802 PSFCTKPITCKDELAPPTLHLDFRDKLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLE 16861

Query: 861   TANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQET---TGTPRSDTVPSPRD----L 913
               +  T     P       I A   +     VV++  T    G  + + V  P      +
Sbjct: 16862 --DDRTHIKTTPATLALEKIKAKRSDSGKYCVVVENSTGSRKGFCQVNVVDRPGPPVGPV 16919

Query: 914   QFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPGEHGQRLPI---SRNTFAEVTG 966
              F EVT   + I W PP     S +T Y ++   V         +P+   S  T  +V+ 
Sbjct: 16920 SFDEVTKDYMVISWKPPLDDGGSKITNYIIEKKEVG----KDVWMPVTSASAKTTCKVSK 16975

Query: 967   LSPGVTYYFKVFAVSHGRESKPLTAQQTTKLD------APTNLQFVNETDSTVLVRWTPP 1020
             L  G  Y F++ A +    S PL +      D      AP        T  + LV W  P
Sbjct: 16976 LLEGKDYIFRIHAENLYGISDPLVSDSMKAKDRFRVPDAPDQPIVTEVTKDSALVTWNKP 17035

Query: 1021  R---AQITGYRLTVGLTRRGQPRQYNVGP--SVSKYPLRNLQPASEYTVSLVA---IKGN 1072
                   IT Y L    T   +  +    P    +K+ + +L    +Y   + A   I   
Sbjct: 17036 HDGGKPITNYILEKRETMSKRWARVTKDPIHPYTKFRVPDLLEGCQYEFRVSAENEIGIG 17095

Query: 1073  QESPKATGVFTTLQPGSSIPPYNTEVTETT---IVITWTPAPR-------IGFKLGVRPS 1122
               SP +  VF         PP N E  +TT   + +TW P PR       +G+ +  +  
Sbjct: 17096 DPSPPSKPVFAKDPIAKPSPPVNPEAIDTTCNSVDLTWQP-PRHDGGSKILGYIVEYQ-K 17153

Query: 1123  QGGEAPREVTSDSGSIV-----VSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTP---L 1174
              G E  R       S       V+GL  G  Y + +  +    E D   V + V     L
Sbjct: 17154 VGDEEWRRANHTPESCPETKYKVTGLRDGQTYKFRVLAVNAAGESDPAHVPEPVLVKDRL 17213

Query: 1175  SPPTNLHLEANP---------DTGVLT----------VSWERSTTPDITGYRITTTPTNG 1215
              PP  L L+AN          DT  L+          V+W++      T  RI  TP   
Sbjct: 17214 EPP-ELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARIDVTPVGS 17272

Query: 1216  QQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRF 1275
             +    +    H D    +    +P     VSV  +  DK              PP DL  
Sbjct: 17273 KL--EIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDKPG------------PPRDLEV 17318

Query: 1276  TNIGPDTMRVTWAPPPSID---LTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGT 1332
             + I  D+  +TW  P       +TN++V    V + +  + LS +    +    +L  G 
Sbjct: 17319 SEIRKDSCYLTWKEPLDDGGSVITNYVVERRDVASAQ-WSPLSATSKKKSHFAKHLNEGN 17377

Query: 1333  EYVVSVSSVYEQHESTPLRGRQKT--GLDS------PTGIDFSDITANSFTVHWIAPR-- 1382
             +Y+  V++   Q+   P     K    LD       P  +   D+     ++ W  P   
Sbjct: 17378 QYLFRVAAE-NQYGRGPFVETPKPIKALDPLHPPGPPKDLHHVDVDKTEVSLVWNKPDRD 17436

Query: 1383  --ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN----GREE 1436
               + ITGY + +  E      +   V +      +T L  G  Y   + A N    G  +
Sbjct: 17437 GGSPITGYLVEYQEEGTQDWIKFKTVTNLE--CVVTGLQQGKTYRFRVKAENIVGLGLPD 17494

Query: 1437  SPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTV 1496
             + + I  Q  +  VP  +E+       L++       TVR+  I  G      P  ++T 
Sbjct: 17495 TTIPIECQEKL--VPPSVELDVKLIEGLVVK---AGTTVRFPAIIRGVP---VPTAKWTT 17546

Query: 1497  PGSK---------------STATISGL--KPGVDYTITVYAVTGRGDSPASSKPISINYR 1539
              GS+               S  TI     +   +Y ITV        + A SK ++++  
Sbjct: 17547 DGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEYQITV-------SNAAGSKTVAVHL- 17598

Query: 1540  TEIDKPSQ----MQVTDVQDNSISVKWLP----SSSPVTGYRVTT--TPKNGPGPTKTKT 1589
             T +D P      + + DV    +++ W P      SPV  Y V    T K+  G     +
Sbjct: 17599 TVLDVPGPPTGPINILDVTPEHMTISWQPPKDDGGSPVINYIVEKQDTRKDTWGVV---S 17655

Query: 1590  AGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDR------PKGLAFTDV 1643
             +G  +T++ I  LQ   EYV  V A+N  G   PL  T      +      P     TD+
Sbjct: 17656 SGSSKTKLKIPHLQKGCEYVFRVRAENKIGVGPPLDSTPTVAKHKFSPPSPPGKPVVTDI 17715

Query: 1644  DVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQ----GLRPGSEYT 1699
               ++  ++W  P+         Y      +   +   + +   A+L+    GL  G+ Y 
Sbjct: 17716 TENAATVSWTLPKSDGGSPITGYYMERREVTGKWVRVN-KTPIADLKFRVTGLYEGNTYE 17774

Query: 1700  VSVVALH------DDMESQPLIGTQSTAIPA-PTDLKFTQVTPTSLSAQWTPP----NVQ 1748
               V A +          S P+   +    P  P + K    +  +    WT P       
Sbjct: 17775 FRVFAENLAGLSKPSPSSDPIKACRPIKPPGPPINPKLKDKSRETADLVWTKPLSDGGSP 17834

Query: 1749  LTGYRVRVTPKEKTGPMKEINLAP--DSSSVVVSGLMVATKYEVSVYALKDTLTSRP--- 1803
             + GY V    K  T     IN        +  V GL+   +Y   + A        P   
Sbjct: 17835 ILGYVVE-CQKPGTAQWNRINKDELIRQCAFRVPGLIEGNEYRFRIKAANIVGEGEPREL 17893

Query: 1804  AQGVVTTLENVSPPR-------RARVTDATETTITISWRTK-------TETITG------ 1843
             A+ V+   + + PP        R  +T     TI I  R K       T T  G      
Sbjct: 17894 AESVIAK-DILHPPEVELDVTCRDVITVRVGQTIRILARVKGRPEPDITWTKEGKVLVRE 17952

Query: 1844  FQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAI 1903
              +VD +    +  +Q  IK  VR+           Y I     + +A+ S +V      +
Sbjct: 17953 KRVDLIQDLPRVELQ--IKEAVRA-------DHGKYIISAKNSSGHAQGSAIV----NVL 17999

Query: 1904  DAP---SNLRFLATTPNSLLVSWQPP----RARITGYIIKYEKPGSPPREVVPRPRPGVT 1956
             D P    NL+    T  +  +SW+ P     + IT +I++Y KP      +V      VT
Sbjct: 18000 DRPGPCQNLKVTNVTKENCTISWENPLDNGGSEITNFIVEYRKPNQKGWSIV---ASDVT 18056

Query: 1957  EATI-TGLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQKTPFVTHPG 2002
             +  I   L    EY   V A +N     P I  K  +     +  PG
Sbjct: 18057 KRLIKANLLANNEYYFRVCA-ENKVGVGPTIETKTPILAINPIDRPG 18102



 Score = 88.2 bits (217), Expect = 9e-17
 Identities = 260/1214 (21%), Positives = 438/1214 (36%), Gaps = 158/1214 (13%)

Query: 908   PSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPIS------RNTF 961
             P    L   EVT  K  + W PP     G ++D   V        RL  +      + T 
Sbjct: 21557 PPEGPLAVTEVTSEKCVLSWFPPLDD-GGAKIDHYIVQ--KRETSRLAWTNVASEVQVTK 21613

Query: 962   AEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKL------DAPTNLQFVNETDSTVLV 1015
              +VT L  G  Y F+V AV+     +PL ++    +      D P N +    T  +++V
Sbjct: 21614 LKVTKLLKGNEYIFRVMAVNKYGVGEPLESEPVLAVNPYGPPDPPKNPEVTTITKDSMVV 21673

Query: 1016  RWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVS-----KYPLRNLQPASEYTVSLVAIK 1070
              W  P +      +   + RR +  Q  +  +       +Y +  L    EY   ++A  
Sbjct: 21674 CWGHPDSDGGSEIINYIVERRDKAGQRWIKCNKKTLTDLRYKVSGLTEGHEYEFRIMAEN 21733

Query: 1071  -GNQESPKATGVF-----TTLQPGSSIPPYNTEVTET---TIVITWTP------APRIGF 1115
                  +P  T  F     T  +PG   PP N  V +T   +I I W        +   G+
Sbjct: 21734 AAGISAPSPTSPFYKACDTVFKPG---PPGNPRVLDTSRSSISIAWNKPIYDGGSEITGY 21790

Query: 1116  KLGVRPSQGGEAPREVTSDSG----SIVVSGLTPGVEYVYTIQVLRD---GQERDAPIVN 1168
              + +   +  E  + VT  +G    S  ++GLT   EY   I  +     G+    P   
Sbjct: 21791 MVEIALPEEDEW-QIVTPPAGLKATSYTITGLTENQEYKIRIYAMNSEGLGEPALVPGTP 21849

Query: 1169  KVVTPLSPP-TNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHA 1227
             K    + PP   L  +      +      R   P I G            G SL++    
Sbjct: 21850 KAEDRMLPPEIELDADLRKVVTIRACCTLRLFVP-IKGRPAPEVKWARDHGESLDKASIE 21908

Query: 1228  DQSSCTFDNLSPGLEYNVSVY--TVKDD--KESVPISDTIIPAVPPPTDLRFTNIGPDTM 1283
               SS T   +     ++   Y  TV++    +S  ++  ++    PP DL+   +   ++
Sbjct: 21909 STSSYTLLIVGNVNRFDSGKYILTVENSSGSKSAFVNVRVLDTPGPPQDLKVKEVTKTSV 21968

Query: 1284  RVTWAPPPSIDLTNFLVRYSPVKNE---EDVAELSISPSDNAVVLTNLLPGTEYVVSVSS 1340
              +TW  PP +D  + +  Y   K E   +  + ++ +    +  +  L  G  Y   V +
Sbjct: 21969 TLTW-DPPLLDGGSKIKNYIVEKRESTRKAYSTVATNCHKTSWKVDQLQEGCSYYFRVLA 22027

Query: 1341  VYEQHESTPLRGRQKTGLDS----PTGIDFSDITANSFTVHWIAPR----ATITGYRIRH 1392
               E     P    +          P  I   D+T NS ++ W  P     + I GY +  
Sbjct: 22028 ENEYGIGLPAETAESVKASERPLPPGKITLMDVTRNSVSLSWEKPEHDGGSRILGYIVEM 22087

Query: 1393  HPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPR 1452
               +          V       T+T L  G EY   + A N   E  +   +Q +V  + +
Sbjct: 22088 QTKGSDKWATCATV--KVTEATITGLIQGEEYSFRVSAQN---EKGISDPRQLSVPVIAK 22142

Query: 1453  DLEVVAA------TPTSLL---ISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTA 1503
             DL +  A      T T L    +  D P +      +T+ +   N P+++ T   ++ST 
Sbjct: 22143 DLVIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHK--DNVPLKQTTRVNAESTE 22200

Query: 1504  --TISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKP----SQMQVTDVQDNS 1557
               ++  +K      +  Y V     +  + + +++     +DKP      +++ +V  +S
Sbjct: 22201 NNSLLTIKDACREDVGHYVVKLTNSAGEAIETLNV---IVLDKPGPPTGPVKMDEVTADS 22257

Query: 1558  ISVKWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEG--LQPTVEYVVS 1611
             I++ W P      S +  Y V    K     T  +         TI+   L+   EY   
Sbjct: 22258 ITLSWGPPKYDGGSSINNYIV---EKRDTSTTTWQIVSATVARTTIKACRLKTGCEYQFR 22314

Query: 1612  VYAQNPSGE-----SQPLVQTAVTNIDRPKGLAFTDVDV-DSIKIAWESPQGQVSRYRVT 1665
             + A+N  G+     S+P V      +  P G     +   DS+++ W  P        + 
Sbjct: 22315 IAAENRYGKSTYLNSEPTVAQYPFKVPGPPGTPVVTLSSRDSMEVQWNEPISDGGSRVIG 22374

Query: 1666  YSSPEDGIHELF-------PAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQ 1718
             Y       + +        P P  +  T    GL  G EY   V A +     +P   ++
Sbjct: 22375 YHLERKERNSILWVKLNKTPIPQTKFKTT---GLEEGVEYEFRVSAENIVGIGKPSKVSE 22431

Query: 1719  STAIPAPTD----LKFTQVTPTSLSAQWTPPNV----QLTGYRVRVTPKEKTGPMKEINL 1770
                   P D     +   VT  S++ QW  P      ++TGY V      +   MK    
Sbjct: 22432 CYVARDPCDPPGRPEAIIVTRNSVTLQWKKPTYDGGSKITGYIVEKKELPEGRWMKASFT 22491

Query: 1771  APDSSSVVVSGLMVATKYEVSVYALKDT-LTSRPAQ--GVVTTLENVSPPRRARVTDATE 1827
                 +   V+GL+   +YE  V A     + S P++  G +T  + V PPR +      +
Sbjct: 22492 NIIDTHFEVTGLVEDHRYEFRVIARNAAGVFSEPSESTGAITARDEVDPPRISMDPKYKD 22551

Query: 1828  TTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQ-PGTDYKIYLYTL 1886
             T +  +  +       F+VDA       P  + IK D        L+   TD+   L ++
Sbjct: 22552 TIVVHAGES-------FKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSL-SV 22603

Query: 1887  NDNAR--SSPVVIDASTAIDAPS---NLRFL-------------ATTPNSLLVSWQPP-- 1926
              D  R  S   ++ A       S   N++ L               T     ++W+PP  
Sbjct: 22604 KDAVRVDSGNYILKAKNVAGERSVTVNVKVLDRPGPPEGPVVISGVTAEKCTLAWKPPLQ 22663

Query: 1927  --RARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEP 1984
                + I  YI++  +       VV           +T L  G EYT  ++A+      EP
Sbjct: 22664 DGGSDIINYIVERRETSRLVWTVVD-ANVQTLSCKVTKLLEGNEYTFRIMAVNKYGVGEP 22722

Query: 1985  LIGRKKTVQKTPFV 1998
             L   +  V K PFV
Sbjct: 22723 L-ESEPVVAKNPFV 22735



 Score = 86.3 bits (212), Expect = 3e-16
 Identities = 274/1330 (20%), Positives = 481/1330 (36%), Gaps = 177/1330 (13%)

Query: 812   DAPPDPT----VDQVDDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETAN 863
             D P  PT    +  + + S+ ++W  P+    + +T Y ++   +     TE++      
Sbjct: 26568 DRPGPPTGPVVISDITEESVTLKWEPPKYDGGSQVTNYILLKRETSTAVWTEVSATVART 26627

Query: 864   SVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFV-EVTDVK 922
              + +  L  G +Y   I A  EN+      I           T P P    +V  VT   
Sbjct: 26628 MMKVMKLTTGEEYQFRIKA--ENRFGISDHIDSACVTVKLPYTTPGPPSTPWVTNVTRES 26685

Query: 923   VTIMWTPPES----AVTGYRVDVIPVN-LPGEHGQRLPISRNTFAEVTGLSPGVTYYFKV 977
             +T+ W  P S    AV GY +++   N +  +   +L I R T  +VT +S G+ Y F+V
Sbjct: 26686 ITVGWHEPVSNGGSAVVGYHLEMKDRNSILWQKANKLVI-RTTHFKVTTISAGLIYEFRV 26744

Query: 978   FAVSHGRESKPL-TAQQTTKLDA---PTNLQFVNETDSTVLVRWTPPR----AQITGYRL 1029
             +A +     KP   ++    +DA   P N++  + + ++V + W  P     ++ITGY  
Sbjct: 26745 YAENAAGVGKPSHPSEPVLAIDACEPPRNVRITDISKNSVSLSWQQPAFDGGSKITGYI- 26803

Query: 1030  TVGLTRRGQP-----RQYNVGPSVSKYPLRNLQPASEYTVSLVA--IKGNQESP-KATGV 1081
                + RR  P     +      + +++ +  L   S+Y   + A    G+  +P +  G 
Sbjct: 26804 ---VERRDLPDGRWTKASFTNVTETQFIISGLTQNSQYEFRVFARNAVGSISNPSEVVGP 26860

Query: 1082  FTTLQ----PGSSIPPYNTEVTE----TTIV----ITWTPAPRI-GFKLGVRPSQGGEAP 1128
              T +     P   +P   TEV +    T++     I+  PAP I  +K            
Sbjct: 26861 ITCIDSYGGPVIDLPLEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVC 26920

Query: 1129  REVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDT 1188
              E T+D  SI++          Y +++        A I  +++    PP           
Sbjct: 26921 VENTTDLASILIKDADRLNSGCYELKLRNAMGSASATIRVQILDKPGPPGGPIEFKTVTA 26980

Query: 1189  GVLTVSWERSTTPD----ITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYN 1244
               +T+ W R    D    IT Y +    T+    + + E  H ++   T   +  G EY 
Sbjct: 26981 EKITLLW-RPPADDGGAKITHYIVEKRETSRVVWSMVSE--HLEECIITTTKIIKGNEYI 27037

Query: 1245  VSVYTVKDDKESVPI-SDTIIP-----AVPPPTDLRFTNIGPDTMRVTWAPP---PSIDL 1295
               V  V       P+ SD+++         PP     T I  ++M V W+ P      D+
Sbjct: 27038 FRVRAVNKYGIGEPLESDSVVAKNAFVTPGPPGIPEVTKITKNSMTVVWSRPIADGGSDI 27097

Query: 1296  TNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEY---VVSVSSVYEQHESTPLRG 1352
             + + +     K+      L  +  D    +T L   ++Y   V +V++  +   S P   
Sbjct: 27098 SGYFLEKRDKKSLGWFKVLKETIRDTRQKVTGLTENSDYQYRVCAVNAAGQGPFSEPSEF 27157

Query: 1353  RQKTGLDSPTG----IDFSDITANSFTVHWIAP----RATITGYRIRHHPEHFSGRPRED 1404
              +      P G    I  +D T +S T+ W  P     + +TGY +    E   G   E 
Sbjct: 27158 YKAADPIDPPGPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVV----EIRQGEEEEW 27213

Query: 1405  RVPHSRNSITLT-----NLTPGTEYVVSIVALN-GREESPLLIGQQSTVSDVPR----DL 1454
                 ++  +  T     NL PG  Y   + A+N   +  P+ + +     D+      DL
Sbjct: 27214 TTVSTKGEVRTTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQAKDILEAPEIDL 27273

Query: 1455  EVVAATPTSLLISWDA-----------PAVTVRYYRITYGETGGNSPVQEFTVPGSKSTA 1503
             +V   T        D            P VT R      G     S         S S  
Sbjct: 27274 DVALRTSVIAKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYS----IENTDSSSLL 27329

Query: 1504  TISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPS---QMQVTDVQDNSISV 1560
             TI  +         +    G G+  +S+  + +     +D P+   ++QV  V   ++++
Sbjct: 27330 TIPQVTRNDTGKYILTIENGVGEPKSSTVSVKV-----LDTPAACQKLQVKHVSRGTVTL 27384

Query: 1561  KWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGP-DQTEMTIEGLQPTVEYVVSVYAQ 1615
              W P      SP+  Y +    ++    T +  +     T   +  L     +   V A+
Sbjct: 27385 LWDPPLIDGGSPIINYVI--EKRDATKRTWSVVSHKCSSTSFKLIDLSEKTPFFFRVLAE 27442

Query: 1616  NPSGESQPLVQT---AVTNIDRP-KGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPED 1671
             N  G  +P   T       +  P + L+  D    S+ ++W  P          Y     
Sbjct: 27443 NEIGIGEPCETTEPVKAAEVPAPIRDLSMKDSTKTSVILSWTKPDFDGGSVITEYVVERK 27502

Query: 1672  GIHELFPAPDGEEDTAELQ--GLRPGSEYTVSVVALHDDMESQPL-IGTQSTAIPAPTDL 1728
             G  E   +  G   T E++   L+  S     V A ++   S P+ IG        P  +
Sbjct: 27503 GKGEQTWSHAGISKTCEIEVSQLKEQSVLEFRVFAKNEKGLSDPVTIG--------PITV 27554

Query: 1729  KFTQVTP-TSLSAQWTPPNVQLT---GYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMV 1784
             K   +TP   LS     P  Q+T   G+ V +    K  P   I+   D   +  S  + 
Sbjct: 27555 KELIITPEVDLS---DIPGAQVTVRIGHNVHLELPYKGKPKPSISWLKDGLPLKESEFVR 27611

Query: 1785  ATKYEVSV-YALKDTLTSRPAQ------------GVVTTLENVSPPRR----ARVTDATE 1827
              +K E  +  ++K+       +             V  T+  + PP +     R  +   
Sbjct: 27612 FSKTENKITLSIKNAKKEHGGKYTVILDNAVCRIAVPITVITLGPPSKPKGPIRFDEIKA 27671

Query: 1828  TTITISWRTKTET----ITGFQVDAVPANGQTPIQRTIKPDVR-SYTITGLQPGTDYKIY 1882
              ++ +SW    +     IT + ++      QT  +       R ++ +  L    +Y+  
Sbjct: 27672 DSVILSWDVPEDNGGGEITCYSIEK-RETSQTNWKMVCSSVARTTFKVPNLVKDAEYQFR 27730

Query: 1883  LYTLNDNARSSPVVIDASTA------IDAPSNLRFLATTPNSLLVSWQPP----RARITG 1932
             +   N    S P+V     A         P        T + + ++W  P     + +TG
Sbjct: 27731 VRAENRYGVSQPLVSSIIVAKHQFRIPGPPGKPVIYNVTSDGMSLTWDAPVYDGGSEVTG 27790

Query: 1933  YIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTV 1992
             + ++ ++  S   + V        E   TGL  G +Y   V A  +   S P    K T+
Sbjct: 27791 FHVEKKERNSILWQKVNTSPISGREYRATGLVEGLDYQFRVYAENSAGLSSPSDPSKFTL 27850

Query: 1993  QKTPFVTHPG 2002
               +P V  PG
Sbjct: 27851 AVSP-VDPPG 27859



 Score = 84.3 bits (207), Expect = 1e-15
 Identities = 337/1686 (19%), Positives = 592/1686 (35%), Gaps = 300/1686 (17%)

Query: 628   IQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISI 684
             + W+ P+    S I+ +I+  R    +  W++  I    +   I GL  G  Y+ ++I+ 
Sbjct: 15215 LNWSDPEDDGGSEITGFIIE-RKDAKMHTWRQP-IETERSKCDITGLLEGQEYKFRVIAK 15272

Query: 685   QQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWV--- 741
              ++G                PV    +        P      + TE T S+  + W    
Sbjct: 15273 NKFG-------------CGPPVEIGPILAVDPLGPPTSPERLTYTERTKSTITLDWKEPR 15319

Query: 742   -SASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQS 800
              +    + G+ +E    ++ D  +        TS  + +L   + Y   V  ++E GE  
Sbjct: 15320 SNGGSPIQGYIIEKRRHDKPDFERVNKRLCPTTSFLVENLDEHQMYEFRVKAVNEIGESE 15379

Query: 801   LILSTSQTTAPDAPPDPTVD---QVDDTSIVVRWSRP---QAPITGYRIVYSPSVEGSST 854
               L  +     D  P PT+     V   +I V+   P    A +TG  +   P +E S  
Sbjct: 15380 PSLPLNVVIQDDEVP-PTIKLRLSVRGDTIKVKAGEPVHIPADVTGLPM---PKIEWSKN 15435

Query: 855   E--LNLPETANSVTLSDLQPG-VQYNITI-YAVEENQESTPVVIQQETTGTPRS------ 904
             E  +  P  A  +T  ++     +  ++I  AV E++ +  V          R+      
Sbjct: 15436 ETVIEKPTDALQITKEEVSRSEAKTELSIPKAVREDKGTYTVTASNRLGSVFRNVHVEVY 15495

Query: 905   DTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPGEHGQRLPISRNT 960
             D    PR+L   ++      + W  P     S +T Y +D    +      + +    NT
Sbjct: 15496 DRPSPPRNLAVTDIKAESCYLTWDAPLDNGGSEITHYVIDKRDASRKKAEWEEVT---NT 15552

Query: 961   FAE----VTGLSPGVTYYFKV-----FAVSHGRESKPLTAQQTTKLDAPTNL-QFVNETD 1010
               E    +  L P   Y F+V     + +S   +S  +  Q   +L  P    + +  T 
Sbjct: 15553 AVEKRYGIWKLIPNGQYEFRVRAVNKYGISDECKSDKVVIQDPYRLPGPPGKPKVLARTK 15612

Query: 1011  STVLVRWTPP----RAQITGYRLTVGLTRRGQPRQY----------NVGPSVSKYPLRNL 1056
              ++LV WTPP     + ITGY     L +R +   Y           VG    ++ +  L
Sbjct: 15613 GSMLVSWTPPLDNGGSPITGY----WLEKREEGSPYWSRVSRAPITKVGLKGVEFNVPRL 15668

Query: 1057  QPASEYTVSLVAIKG------NQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPA 1110
                 +Y    +AI        ++ S           PG    P   + T+++I + W P 
Sbjct: 15669 LEGVKYQFRAMAINAAGIGPPSEPSDPEVAGDPIFPPGPPSCPEVKDKTKSSISLGWKPP 15728

Query: 1111  PRIGFKLGVRPSQG--GEAPREVTSD------------SGSIVVSGLTPGVEYVYTIQVL 1156
                  K G  P +G   E   E T+D            +   VV  L    +Y + ++ +
Sbjct: 15729 A----KDGGSPIKGYIVEMQEEGTTDWKRVNEPDKLITTCECVVPNLKELRKYRFRVKAV 15784

Query: 1157  RD-GQERDAPIVNKV-VTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPT- 1213
              + G+   +    ++  T +     + ++      ++  +  +   P +   R T   + 
Sbjct: 15785 NEAGESEPSDTTGEIPATDIQEEPEVFIDIGAQDCLVCKAGSQIRIPAVIKGRPTPKSSW 15844

Query: 1214  --NGQQGNSLEEVVH---ADQSSCTFDNLSPGL----------EYNVSVYTVKDDKESVP 1258
               +G+   ++++ VH    D    T +N S  +          +Y+++    K  +++  
Sbjct: 15845 EFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECKRSHTGKYSITAKN-KAGQKTAN 15903

Query: 1259  ISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEED-VAELSIS 1317
                 ++    PP DL+ ++I   + R++W  P   D  + +  Y   K   D  A   ++
Sbjct: 15904 CRVKVMDVPGPPKDLKVSDITRGSCRLSWKMPDD-DGGDRIKGYVIEKRTIDGKAWTKVN 15962

Query: 1318  P--SDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGL-------DSPTGIDFSD 1368
             P       V+ +LL   +Y   V +        P+   Q+T         D P  +    
Sbjct: 15963 PDCGSTTFVVPDLLSEQQYFFRVRAENRFGIGPPVETIQRTTARDPIYPPDPPIKLKIGL 16022

Query: 1369  ITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPRED-RVPHSRN----SITLTNLT 1419
             IT N+  + W  P+    + +T Y +       +G  +E  R  + R+      T+ +L 
Sbjct: 16023 ITKNTVHLSWKPPKNDGGSPVTHYIVECLAWDPTGTKKEAWRQCNKRDVEELQFTVEDLV 16082

Query: 1420  PGTEYVVSIVALN--GREESPLLIG-------QQSTVSDVPRDLEVVAATPTSLLIS-WD 1469
              G EY   + A+N  G  +    +G             D+   +EV   T  +++     
Sbjct: 16083 EGGEYEFRVKAVNAAGVSKPSATVGPCDCQRPDMPPSIDLKEFMEVEEGTNVNIVAKIKG 16142

Query: 1470  APAVTVRYYRITYGETGGNSPVQEFT-----VPGSKSTATISGLKPGVDYTITVYAVTGR 1524
              P  T+ +++    +     PV   T     V     T  I   +       T+ AV   
Sbjct: 16143 VPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDTGLYTITAVNNL 16202

Query: 1525  GDSPASSKPISINYRTEIDKP-SQMQVTDVQDNSISVKWLP----SSSPVTGYRVTTTPK 1579
             G    +SK + +N       P   ++   V  + +++ W P      S +T Y +     
Sbjct: 16203 G---TASKEMRLNVLGRPGPPVGPIKFESVSADQMTLSWFPPKDDGGSKITNYVIEKREA 16259

Query: 1580  NGPGPTKT---KTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVT--NI-- 1632
             N     KT    ++ P +   TI  L    EYV  + AQN  G  +PL     T  N+  
Sbjct: 16260 N----RKTWVHVSSEPKECTYTIPKLLEGHEYVFRIMAQNKYGIGEPLDSEPETARNLFS 16315

Query: 1633  --DRPKGLAFTDVDVDSIKIAWESPQ----GQVSRYRVTYSSPEDGIHELFPAPDGEEDT 1686
                 P     + V  +S+ + WE P+      V+ Y   +   +D   + +   + +   
Sbjct: 16316 VPGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPVTGY---WLEMKDTTSKRWKRVNRDPIK 16372

Query: 1687  A-------ELQGLRPGSEYTVSVVALH------DDMESQPLIGTQSTAIPAPTDLKFTQV 1733
             A       ++ GL  GS+Y   V A++        + S P       A P P   K T  
Sbjct: 16373 AMTLGVSYKVTGLIEGSDYQFRVYAINAAGVGPASLPSDPATARDPIAPPGPPFPKVTDW 16432

Query: 1734  TPTSLSAQWTPP----NVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYE 1789
             T +S   +W+PP      ++TGY V    + K    K  +     + +VV+GL     Y+
Sbjct: 16433 TKSSADLEWSPPLKDGGSKVTGYIVEYKEEGKEEWEKGKDKEVRGTKLVVTGLKEGAFYK 16492

Query: 1790  VSVYALKDTLTSRPAQGVVTTLEN----VSPPRR--ARVTD----------------ATE 1827
               V A+       P + V   +E     VSP  +  A V D                + +
Sbjct: 16493 FRVRAVNIAGIGEPGE-VTDVIEMKDRLVSPDLQLDASVRDRIVVHAGGVIRIIAYVSGK 16551

Query: 1828  TTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDV--RSYTITGLQPGTDYKIYLYT 1885
                T++W     T+              P + TI+      S  I   Q        L  
Sbjct: 16552 PPPTVTWNMNERTL--------------PQEATIETTAISSSMVIKNCQRSHQGVYSLLA 16597

Query: 1886  LNDNARSSPVVIDASTAIDAPSNLRFLA--TTPNSLLVSWQPPR----ARITGYIIKYEK 1939
              N+       +I     +  P    FLA   T  S  ++W  P     + IT Y+I  EK
Sbjct: 16598 KNEAGERKKTIIVDVLDVPGPVGTPFLAHNLTNESCKLTWFSPEDDGGSPITNYVI--EK 16655

Query: 1940  PGSPPREVVPRPRPGVTE-ATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQKTPFV 1998
               S  R   P       + AT+ GL  G  Y   + A             + ++   PFV
Sbjct: 16656 RESDRRAWTPVTYTVTRQNATVQGLIQGKAYFFRIAA-------------ENSIGMGPFV 16702

Query: 1999  THPGYDTGNGIQLPGTSGQQPSVGQQMIFEEHGFRRTTPPTTATPIRHRPRPYPPNVGQE 2058
                                     + ++  E             PI    RP    V + 
Sbjct: 16703 ---------------------ETSEALVIRE-------------PITVPERPEDLEVKEV 16728

Query: 2059  ALSQTTISWAP--FQDTSE---YIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYN 2113
               +  T++W P  +   SE   Y++    +GT++          S   T+ GL  G TY 
Sbjct: 16729 TKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEKFHKVTNDNLLSRKYTVKGLKEGDTYE 16788

Query: 2114  IIVEAL 2119
               V A+
Sbjct: 16789 YRVSAV 16794



 Score = 84.3 bits (207), Expect = 1e-15
 Identities = 134/644 (20%), Positives = 244/644 (37%), Gaps = 79/644 (12%)

Query: 1421  GTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAP----AVTVR 1476
             G +Y++    + G +  P+ +            ++V   T     ++W  P       + 
Sbjct: 23693 GGQYILRASNVAGSKSFPVNVKVLDRPGPPEGPVQVTGVTSEKCSLTWSPPLQDGGSDIS 23752

Query: 1477  YYRITYGETGGNSPVQEFTVPGSK---STATISGLKPGVDYTITVYAVTGRG-DSPASSK 1532
             +Y +   ET   +    +TV  S+   ++  ++ L  G +Y   + AV   G   P  S 
Sbjct: 23753 HYVVEKRETSRLA----WTVVASEVVTNSLKVTKLLEGNEYVFRIMAVNKYGVGEPLESA 23808

Query: 1533  PISINYRTEID-KPSQMQVTDVQDNSISVKW-LPSS---SPVTGYRVTTTPKNGPGPTKT 1587
             P+ +     +   P  ++VT++  +S++V W  P S   S + GY V    ++G    K 
Sbjct: 23809 PVLMKNPFVLPGPPKSLEVTNIAKDSMTVCWNRPDSDGGSEIIGYIVEKRDRSGIRWIKC 23868

Query: 1588  KTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTA-------VTNIDRPKGLAF 1640
                      + + GL    EY   V A+N +G  +P   T        V     P     
Sbjct: 23869 NKRRITDLRLRVTGLTEDHEYEFRVSAENAAGVGEPSPATVYYKACDPVFKPGPPTNAHI 23928

Query: 1641  TDVDVDSIKIAWESP----QGQVSRYRVTYSSPEDGIHELFPAPDGEEDTA-ELQGLRPG 1695
              D   +SI +AW  P      ++  Y V     ++   ++     G   T  E+  L   
Sbjct: 23929 VDTTKNSITLAWGKPIYDGGSEILGYVVEICKADEEEWQIVTPQTGLRVTRFEISKLTEH 23988

Query: 1696  SEYTVSVVALHDDMESQPLIGT-QSTAIPAPTDLKFTQVTPT-SLSAQWTPPNVQLTGYR 1753
              EY + V AL+        +G  ++T++P     +     P   L ++     V   G  
Sbjct: 23989 QEYKIRVCALNK-------VGLGEATSVPGTVKPEDKLEAPELDLDSELRKGIVVRAGGS 24041

Query: 1754  VRVTPKEKTGPMKEINLAPD----SSSVVVSGLMVATKYEVS----------VYALKDTL 1799
              R+    K  P  EI  + +    +  V +   +  T+  +           +  L+++ 
Sbjct: 24042 ARIHIPFKGRPTPEITWSREEGEFTDKVQIEKGVNYTQLSIDNCDRNDAGKYILKLENSS 24101

Query: 1800  TSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKT----ETITGFQVDAVPANGQT 1855
              S+ A   V  L+   PP+   V +  + +  + W          +  + +D   +  + 
Sbjct: 24102 GSKSAFVTVKVLDTPGPPQNLAVKEVRKDSAFLVWEPPIIDGGAKVKNYVIDKRESTRKA 24161

Query: 1856  PIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPV-VIDASTAIDAPS-----NL 1909
                 + K    S+ +  L  G  Y   +   N+     PV  +DA  A + PS      L
Sbjct: 24162 YANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFGVGVPVETVDAVKAAEPPSPPGKVTL 24221

Query: 1910  RFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEP 1965
               ++ T  SL+  W+ P     +R+ GY+++ +  G+    +V   +  V  A +TGL  
Sbjct: 24222 TDVSQTSASLM--WEKPEHDGGSRVLGYVVEMQPKGTEKWSIVAESK--VCNAVVTGLSS 24277

Query: 1966  GTEYTIYVIALKNNQKSE------PLIGRKKTVQ---KTPFVTH 2000
             G EY   V A     KS+      P+I +  T+Q   K PF T+
Sbjct: 24278 GQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKLPFNTY 24321



 Score = 82.4 bits (202), Expect = 5e-15
 Identities = 130/589 (22%), Positives = 217/589 (36%), Gaps = 70/589 (11%)

Query: 1505  ISGLKPGVDYTITVYAVTGRG-DSPASSKPI-SINYRTEIDKPSQMQVTDVQDNSISVKW 1562
             ++ L  G +YT  + AV   G   P  S+P+ + N     D P   +VT V  +S+ V W
Sbjct: 22698 VTKLLEGNEYTFRIMAVNKYGVGEPLESEPVVAKNPFVVPDAPKAPEVTTVTKDSMIVVW 22757

Query: 1563  -LPSS---SPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPS 1618
               P+S   S + GY +    K G   T+       +  + + GL    +Y   V A+N +
Sbjct: 22758 ERPASDGGSEILGYVLEKRDKEGIRWTRCHKRLIGELRLRVTGLIENHDYEFRVSAENAA 22817

Query: 1619  GESQPLVQTA-------VTNIDRPKGLAFTDVDVDSIKIAWESP----QGQVSRYRVTYS 1667
             G S+P   +A       +     P      D+   S+ ++W  P      ++  Y V   
Sbjct: 22818 GLSEPSPPSAYQKACDPIYKPGPPNNPKVIDITRSSVFLSWSKPIYDGGCEIQGYIVEKC 22877

Query: 1668  SPEDGIHELFPAPDGEEDT-AELQGLRPGSEYTVSVVAL-------HDDMESQPLIGTQS 1719
                 G   +   P G   T  E++ L    EY   + A+       H D+    ++  + 
Sbjct: 22878 DVSVGEWTMCTPPTGINKTNIEVEKLLEKHEYNFRICAINKAGVGEHADVPGPIIVEEKL 22937

Query: 1720  TAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEK----TGPMKEINLAPDSS 1775
              A     DL+  ++                   + R TP+ K     G +++  +   +S
Sbjct: 22938 EAPDIDLDLELRKIINIRAGGSLR----LFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTS 22993

Query: 1776  SVVVSGLMVATKYEVSVY--ALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITIS 1833
             S     L    +Y+   Y   L+++  ++ A   V  L+  SPP   +VT+ T+ +++I+
Sbjct: 22994 SFTSLVLDNVNRYDSGKYTLTLENSSGTKSAFVTVRVLDTPSPPVNLKVTEITKDSVSIT 23053

Query: 1834  WRTKT----ETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDN 1889
             W          I  + V+   A  ++           S+ I  LQ G  Y   +   N+ 
Sbjct: 23054 WEPPLLDGGSKIKNYIVEKREATRKSYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAENEY 23113

Query: 1890  ARSSPV----VIDASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPG 1941
                 P      I  +     P  +     T NS+ +SW  P     ++I  YI++ +   
Sbjct: 23114 GIGLPAQTADPIKVAEVPQPPGKITVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKH 23173

Query: 1942  SPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQKTPFVTHP 2001
             S       R +    +A IT L  G EY   V+A+    +S+P       V K   V  P
Sbjct: 23174 SEKWSECARVKS--LQAVITNLTQGEEYLFRVVAVNEKGRSDPRSLAVPIVAK-DLVIEP 23230

Query: 2002  GYDTGNGIQLPGTSGQQPSVGQQMIFEEHGFRRTTPPTTATPIRHRPRP 2050
                       P  S     VGQ +  E              PI  RP+P
Sbjct: 23231 DVK-------PAFSSYSVQVGQDLKIE-------------VPISGRPKP 23259



 Score = 82.0 bits (201), Expect = 6e-15
 Identities = 266/1310 (20%), Positives = 442/1310 (33%), Gaps = 219/1310 (16%)

Query: 731   ITASSFVVSWVSASDTVSGFRVEYELSE-EGDEPQYLDLPSTAT--SVNIPDLLPGRKYI 787
             ++A    +SW    D        Y + + E +   ++ + S     +  IP LL G +Y+
Sbjct: 16229 VSADQMTLSWFPPKDDGGSKITNYVIEKREANRKTWVHVSSEPKECTYTIPKLLEGHEYV 16288

Query: 788   V-----NVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ----API 838
                   N Y I E  +     + +  + P AP  PTV  V   S+ V W  P+    +P+
Sbjct: 16289 FRIMAQNKYGIGEPLDSEPETARNLFSVPGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPV 16348

Query: 839   TGYRIVYSPSVEGSSTELNLPETANSVTL------SDLQPGVQYNITIYAVEENQESTPV 892
             TGY +    +       +N  +   ++TL      + L  G  Y   +YA+       P 
Sbjct: 16349 TGYWLEMKDTTSKRWKRVN-RDPIKAMTLGVSYKVTGLIEGSDYQFRVYAINAAGVG-PA 16406

Query: 893   VIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPG 948
              +  +          P P   +  + T     + W+PP     S VTGY V+        
Sbjct: 16407 SLPSDPATARDPIAPPGPPFPKVTDWTKSSADLEWSPPLKDGGSKVTGYIVEYKEEGKEE 16466

Query: 949   EHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGR-----------ESKPLTAQQTTKL 997
                 +    R T   VTGL  G  Y F+V AV+              E K        +L
Sbjct: 16467 WEKGKDKEVRGTKLVVTGLKEGAFYKFRVRAVNIAGIGEPGEVTDVIEMKDRLVSPDLQL 16526

Query: 998   DAPTNLQFVNETDSTV----LVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSV--SKY 1051
             DA    + V      +     V   PP        +T  +  R  P++  +  +   S  
Sbjct: 16527 DASVRDRIVVHAGGVIRIIAYVSGKPPPT------VTWNMNERTLPQEATIETTAISSSM 16580

Query: 1052  PLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNT-EVTETTIVITWTP- 1109
              ++N Q + +   SL+A     E  K   V     PG    P+    +T  +  +TW   
Sbjct: 16581 VIKNCQRSHQGVYSLLAKNEAGERKKTIIVDVLDVPGPVGTPFLAHNLTNESCKLTWFSP 16640

Query: 1110  -----APRIGFKLGVRPS-QGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRD----- 1158
                  +P   + +  R S +    P   T    +  V GL  G  Y + I          
Sbjct: 16641 EDDGGSPITNYVIEKRESDRRAWTPVTYTVTRQNATVQGLIQGKAYFFRIAAENSIGMGP 16700

Query: 1159  -GQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSW---ERSTTPDITGYRITTTPTN 1214
               +  +A ++ + +T    P +L ++       +T++W   +     +I  Y + +    
Sbjct: 16701 FVETSEALVIREPITVPERPEDLEVK-EVTKNTVTLTWNPPKYDGGSEIINYVLESRLIG 16759

Query: 1215  GQQGNSLEEVVHADQSSCTFDNLSPG--LEYNVSVYTV----KDDKESVPISDTIIPAVP 1268
              ++ + +    +      T   L  G   EY VS   +    K    + PI  T    + 
Sbjct: 16760 TEKFHKVTN-DNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGKPSFCTKPI--TCKDELA 16816

Query: 1269  PPT---------DLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAE---LSI 1316
             PPT          +R       T R +  P P +         S  K+E DV E     I
Sbjct: 16817 PPTLHLDFRDKLTIRVGEAFALTGRYSGKPKPKV---------SWFKDEADVLEDDRTHI 16867

Query: 1317  SPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSP----TGIDFSDITAN 1372
               +   + L  +            V E    +     Q   +D P      + F ++T +
Sbjct: 16868 KTTPATLALEKIKAKRSDSGKYCVVVENSTGSRKGFCQVNVVDRPGPPVGPVSFDEVTKD 16927

Query: 1373  SFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVP----HSRNSITLTNLTPGTEYVVSI 1428
                + W  P     G +I ++        ++  +P     ++ +  ++ L  G +Y+  I
Sbjct: 16928 YMVISW-KPPLDDGGSKITNYIIEKKEVGKDVWMPVTSASAKTTCKVSKLLEGKDYIFRI 16986

Query: 1429  VALNGREESPLLIG------QQSTVSDVPRDLEVVAATPTSLLISWDAP----------- 1471
              A N    S  L+        +  V D P    V   T  S L++W+ P           
Sbjct: 16987 HAENLYGISDPLVSDSMKAKDRFRVPDAPDQPIVTEVTKDSALVTWNKPHDGGKPITNYI 17046

Query: 1472  -----AVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVT--GR 1524
                   ++ R+ R+T        P  +F VP          L  G  Y   V A    G 
Sbjct: 17047 LEKRETMSKRWARVTKDPI---HPYTKFRVP---------DLLEGCQYEFRVSAENEIGI 17094

Query: 1525  GDSPASSKPISINYRTEIDKPS---QMQVTDVQDNSISVKWLP----SSSPVTGYRVTTT 1577
             GD    SKP+    +  I KPS     +  D   NS+ + W P      S + GY +   
Sbjct: 17095 GDPSPPSKPVFA--KDPIAKPSPPVNPEAIDTTCNSVDLTWQPPRHDGGSKILGY-IVEY 17151

Query: 1578  PKNGPGPTKTKTAGPD---QTEMTIEGLQPTVEYVVSVYAQNPSGESQP-------LVQT 1627
              K G    +     P+   +T+  + GL+    Y   V A N +GES P       LV+ 
Sbjct: 17152 QKVGDEEWRRANHTPESCPETKYKVTGLRDGQTYKFRVLAVNAAGESDPAHVPEPVLVKD 17211

Query: 1628  AV--------TNIDRPKGLAFTDV--------DVDSIKIAWESPQGQVSRYRVTYSSPED 1671
              +         N+ R + +   D          V   K+ W+              +P  
Sbjct: 17212 RLEPPELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARIDVTPVG 17271

Query: 1672  GIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFT 1731
                E+  A   +     L    P    TVSV  L  D                P DL+ +
Sbjct: 17272 SKLEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDKPG------------PPRDLEVS 17319

Query: 1732  QVTPTSLSAQWTPP----NVQLTGYRVR-------------VTPKEKTGPMKEINLAPDS 1774
             ++   S    W  P       +T Y V               T K+K+   K +N     
Sbjct: 17320 EIRKDSCYLTWKEPLDDGGSVITNYVVERRDVASAQWSPLSATSKKKSHFAKHLN----E 17375

Query: 1775  SSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISW 1834
              +  +  +    +Y    +      T +P +  +  L    PP+     D  +T +++ W
Sbjct: 17376 GNQYLFRVAAENQYGRGPF----VETPKPIK-ALDPLHPPGPPKDLHHVDVDKTEVSLVW 17430

Query: 1835  ----RTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYK 1880
                 R     ITG+ V+      Q  I+     ++    +TGLQ G  Y+
Sbjct: 17431 NKPDRDGGSPITGYLVEYQEEGTQDWIKFKTVTNLEC-VVTGLQQGKTYR 17479



 Score = 80.9 bits (198), Expect = 1e-14
 Identities = 248/1194 (20%), Positives = 435/1194 (36%), Gaps = 142/1194 (11%)

Query: 908   PSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAE 963
             P    +Q   VT  K ++ W+PP     S ++ Y V+    +          +  N+  +
Sbjct: 23721 PPEGPVQVTGVTSEKCSLTWSPPLQDGGSDISHYVVEKRETSRLAWTVVASEVVTNSL-K 23779

Query: 964   VTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDA------PTNLQFVNETDSTVLVRW 1017
             VT L  G  Y F++ AV+     +PL +      +       P +L+  N    ++ V W
Sbjct: 23780 VTKLLEGNEYVFRIMAVNKYGVGEPLESAPVLMKNPFVLPGPPKSLEVTNIAKDSMTVCW 23839

Query: 1018  TPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQ---------PASEYTVSLVA 1068
               P +   G    +G     + R        +K  + +L+            E+ VS   
Sbjct: 23840 NRPDSD--GGSEIIGYIVEKRDRSGIRWIKCNKRRITDLRLRVTGLTEDHEYEFRVSAEN 23897

Query: 1069  IKGNQESPKATGVFTTLQPGSSI-PPYNTEVTETT---IVITWTP------APRIGFKLG 1118
               G  E   AT  +    P     PP N  + +TT   I + W        +  +G+ + 
Sbjct: 23898 AAGVGEPSPATVYYKACDPVFKPGPPTNAHIVDTTKNSITLAWGKPIYDGGSEILGYVVE 23957

Query: 1119  VRPSQGGEAPREVTSDSGSIV----VSGLTPGVEYVYTIQVLRD---GQERDAPIVNKVV 1171
             +  +   E  + VT  +G  V    +S LT   EY   +  L     G+    P   K  
Sbjct: 23958 ICKADEEEW-QIVTPQTGLRVTRFEISKLTEHQEYKIRVCALNKVGLGEATSVPGTVKPE 24016

Query: 1172  TPLSPPTNLHLEANPDTGVLT---------VSWERSTTPDITGYRITTTPTNGQQGNSLE 1222
               L  P  L L++    G++          + ++   TP+IT  R     T+  Q   +E
Sbjct: 24017 DKLEAP-ELDLDSELRKGIVVRAGGSARIHIPFKGRPTPEITWSREEGEFTDKVQ---IE 24072

Query: 1223  EVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRFTNIGPDT 1282
             + V+  Q S    + +   +Y + +      K +  ++  ++    PP +L    +  D+
Sbjct: 24073 KGVNYTQLSIDNCDRNDAGKYILKLENSSGSKSAF-VTVKVLDTPGPPQNLAVKEVRKDS 24131

Query: 1283  MRVTWAPPPSIDLTNFLVRYSPVKNEED---VAELSISPSDNAVVLTNLLPGTEYVVSVS 1339
               + W PP  ID    +  Y   K E      A +S   S  +  + NL  G  Y   V 
Sbjct: 24132 AFLVWEPP-IIDGGAKVKNYVIDKRESTRKAYANVSSKCSKTSFKVENLTEGAIYYFRVM 24190

Query: 1340  SVYEQHESTPLR---GRQKTGLDSPTG-IDFSDITANSFTVHWIAPR----ATITGYRIR 1391
             +  E     P+      +     SP G +  +D++  S ++ W  P     + + GY + 
Sbjct: 24191 AENEFGVGVPVETVDAVKAAEPPSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVE 24250

Query: 1392  HHPEHFSGRPREDRVPHSRN-SITLTNLTPGTEYVVSIVALNGREES-PLLIGQQSTVSD 1449
               P+   G  +   V  S+  +  +T L+ G EY   + A N + +S P ++G      D
Sbjct: 24251 MQPK---GTEKWSIVAESKVCNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKD 24307

Query: 1450  VPRDLEVVAATPTSLL-----ISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTAT 1504
             +     +     T  +     +  + P +      I++ + G   P+++ T    + TAT
Sbjct: 24308 LTIQPSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDG--EPLKQTTRVNVEETAT 24365

Query: 1505  --ISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKP-SQMQVTDVQDNSISVK 1561
               +  +K G       Y VT    +  +++ +S+    +   P   ++  +V  + + + 
Sbjct: 24366 STVLHIKEGNKDDFGKYTVTATNSAGTATENLSVIVLEKPGPPVGPVRFDEVSADFVVIS 24425

Query: 1562  WLPSS----SPVTGYRV-----TTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSV 1612
             W P +      ++ Y V     TTT  +    T  +T       + I  L+   EY   +
Sbjct: 24426 WEPPAYTGGCQISNYIVEKRDTTTTTWHMVSATVARTT------IKITKLKTGTEYQFRI 24479

Query: 1613  YAQNPSGESQPLVQTAVT-----NIDRPKGLAF-TDVDVDSIKIAWESPQGQVSRYRVTY 1666
             +A+N  G+S PL   AV          P G  F T +  D + + W  P        + Y
Sbjct: 24480 FAENRYGKSAPLDSKAVIVQYPFKEPGPPGTPFVTSISKDQMLVQWHEPVNDGGTKIIGY 24539

Query: 1667  SSPEDGIHELF-------PAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQS 1719
                +   + +        P  D +  T    GL  G EY   V A +     +P   ++ 
Sbjct: 24540 HLEQKEKNSILWVKLNKTPIQDTKFKTT---GLDEGLEYEFKVSAENIVGIGKPSKVSEC 24596

Query: 1720  TAIPAPTDL----KFTQVTPTSLSAQWTPP----NVQLTGYRVRVTPKEKTGPMKEINLA 1771
                  P D     +   +T  +++ +W  P      ++TGY V          MK     
Sbjct: 24597 FVARDPCDPPGRPEAIVITRNNVTLKWKKPAYDGGSKITGYIVEKKDLPDGRWMKASFTN 24656

Query: 1772  PDSSSVVVSGLMVATKYEVSVYALKDTLT-SRPAQ--GVVTTLENVSPPRRAR------- 1821
                +   VSGL+   +YE  V A       S P+   G +T  + +  P  +        
Sbjct: 24657 VLETEFTVSGLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARDEIDAPNASLDPKYKDV 24716

Query: 1822  -VTDATET-TITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQP-GTD 1878
              V  A ET  +    R K      +  D      +T  +  IK  ++  T+       TD
Sbjct: 24717 IVVHAGETFVLEADIRGKPIPDVVWSKDGKELE-ETAARMEIKSTIQKTTLVVKDCIRTD 24775

Query: 1879  YKIYLYTLND--NARSSPVVIDASTAIDAPSN-LRFLATTPNSLLVSWQPPR----ARIT 1931
                Y+  L++    +S P+ +        P   L+    T     ++W PP     A I+
Sbjct: 24776 GGQYILKLSNVGGTKSIPITVKVLDRPGPPEGPLKVTGVTAEKCYLAWNPPLQDGGANIS 24835

Query: 1932  GYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPL 1985
              YII+  +        V      +    +T L PG EY   V+A+      EPL
Sbjct: 24836 HYIIEKRETSRLSWTQVSTEVQALNYK-VTKLLPGNEYIFRVMAVNKYGIGEPL 24888



 Score = 78.6 bits (192), Expect = 7e-14
 Identities = 169/767 (22%), Positives = 275/767 (35%), Gaps = 120/767 (15%)

Query: 601   PLQTYPSSSGPVEVFITETPSQPN-------SHPIQWNAPQ---PSHISKYILRWRPKNS 650
             P +T P       VF+   PS+P        +  I W  P     + I+ Y + ++  + 
Sbjct: 26068 PSETSPLIRAEDPVFLPSPPSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEYKKSDD 26127

Query: 651   VGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNT 710
                WK +        YTI GL  G  Y  ++ S+ + G  +        + +S P  +  
Sbjct: 26128 TD-WKTSIQSLRGTEYTISGLTTGAEYVFRVKSVNKVGASD-------PSDSSDPQIAKE 26179

Query: 711   VTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVS--GFRVEYELSEEGDEP----Q 764
                E     PL       +E+  +  V +  S + TV   G  V   L  + D       
Sbjct: 26180 REEE-----PLFDID---SEMRKTLIVKAGASFTMTVPFRGRPVPNVLWSKPDTDLRTRA 26231

Query: 765   YLDLPSTATSVNIPDLL--PGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQV 822
             Y+D   + TS+ I +       KY + +  +      +L++    T  P  P + TV  V
Sbjct: 26232 YVDTTDSRTSLTIENANRNDSGKYTLTIQNVLSAASLTLVVKVLDTPGP--PTNITVQDV 26289

Query: 823   DDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNI 878
                S V+ W  P+    AP+  Y I    + + +   +       S  +++LQ G  Y  
Sbjct: 26290 TKESAVLSWDVPENDGGAPVKNYHIEKREASKKAWVSVTNNCNRLSYKVTNLQEGAIYYF 26349

Query: 879   TIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAV 934
              +    E     P   ++   G   ++    P  L    ++   V++ W  PE    S +
Sbjct: 26350 RVSGENEFGVGIPAETKE---GVKITEKPSPPEKLGVTSISKDSVSLTWLKPEHDGGSRI 26406

Query: 935   TGYRVDVIPVNLPGEHGQR----LPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKP-- 988
               Y V+ +      E GQ+      ++++T   V+GL     Y+F+VFA +    S P  
Sbjct: 26407 VHYVVEAL------EKGQKNWVKCAVAKSTHHVVSGLRENSEYFFRVFAENQAGLSDPRE 26460

Query: 989   -LTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPS 1047
              L      +   P  +   N    TV VR         G  L V +   G+P    V  S
Sbjct: 26461 LLLPVLIKEQLEPPEIDMKNFPSHTVYVR--------AGSNLKVDIPISGKPLP-KVTLS 26511

Query: 1048  VSKYPLR-NLQPASEYTV---------SLVAIKGNQESPKATGVFTTL---------QPG 1088
                 PL+  ++  +E T          S+ A  G  E   A    TT          +PG
Sbjct: 26512 RDGVPLKATMRFNTEITAENLTINLKESVTADAGRYEITAANSSGTTKAFINIVVLDRPG 26571

Query: 1089  SSI-PPYNTEVTETTIVITWTPAPRIG-------FKLGVRPSQGGEAPREVTSDSGSIVV 1140
                 P   +++TE ++ + W P    G         L    S         T     + V
Sbjct: 26572 PPTGPVVISDITEESVTLKWEPPKYDGGSQVTNYILLKRETSTAVWTEVSATVARTMMKV 26631

Query: 1141  SGLTPGVEYVYTIQV-----LRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSW 1195
               LT G EY + I+      + D  +     V    T   PP+   +  N     +TV W
Sbjct: 26632 MKLTTGEEYQFRIKAENRFGISDHIDSACVTVKLPYTTPGPPSTPWV-TNVTRESITVGW 26690

Query: 1196  ERSTT---PDITGYRITTTPTNG---QQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYT 1249
                 +     + GY +     N    Q+ N L  V+       T   +S GL Y   VY 
Sbjct: 26691 HEPVSNGGSAVVGYHLEMKDRNSILWQKANKL--VIRTTHFKVT--TISAGLIYEFRVYA 26746

Query: 1250  V------KDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPP 1290
                    K    S P+    I A  PP ++R T+I  +++ ++W  P
Sbjct: 26747 ENAAGVGKPSHPSEPV--LAIDACEPPRNVRITDISKNSVSLSWQQP 26791



 Score = 77.8 bits (190), Expect = 1e-13
 Identities = 327/1588 (20%), Positives = 561/1588 (35%), Gaps = 285/1588 (17%)

Query: 737   VVSWVSASDT----VSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQ 792
             +++W    D     ++GF +E + ++     Q ++  +  +  +I  LL G++Y   V  
Sbjct: 15214 LLNWSDPEDDGGSEITGFIIERKDAKMHTWRQPIE--TERSKCDITGLLEGQEYKFRVIA 15271

Query: 793   ISEDG-----EQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQA----PITGYRI 843
              ++ G     E   IL+      P +P   T  +   ++I + W  P++    PI GY I
Sbjct: 15272 KNKFGCGPPVEIGPILAVDPLGPPTSPERLTYTERTKSTITLDWKEPRSNGGSPIQGYII 15331

Query: 844   VY----SPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTP-----VVI 894
                    P  E  +  L  P T  S  + +L     Y   + AV E  ES P     VVI
Sbjct: 15332 EKRRHDKPDFERVNKRL-CPTT--SFLVENLDEHQMYEFRVKAVNEIGESEPSLPLNVVI 15388

Query: 895   QQETTG-------TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLP 947
             Q +          + R DT+     ++  E   +   +   P           VI     
Sbjct: 15389 QDDEVPPTIKLRLSVRGDTIK----VKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTD 15444

Query: 948   GEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSH----GRESKPLTAQQTTKLDAPTNL 1003
                  +  +SR+       +   V      + V+     G   + +  +   +   P NL
Sbjct: 15445 ALQITKEEVSRSEAKTELSIPKAVREDKGTYTVTASNRLGSVFRNVHVEVYDRPSPPRNL 15504

Query: 1004  QFVNETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSV--SKYPLRNLQ 1057
                +    +  + W  P     ++IT Y +      R +     V  +    +Y +  L 
Sbjct: 15505 AVTDIKAESCYLTWDAPLDNGGSEITHYVIDKRDASRKKAEWEEVTNTAVEKRYGIWKLI 15564

Query: 1058  PASEYTVSLVAIKGNQESPKATGVFTTLQ-----PGSSIPPYNTEVTETTIVITWTP--- 1109
             P  +Y   + A+     S +       +Q     PG    P     T+ +++++WTP   
Sbjct: 15565 PNGQYEFRVRAVNKYGISDECKSDKVVIQDPYRLPGPPGKPKVLARTKGSMLVSWTPPLD 15624

Query: 1110  ---APRIGFKLGVRP------SQGGEAPREVTSDSG-SIVVSGLTPGVEYVYTIQVLR-- 1157
                +P  G+ L  R       S+   AP       G    V  L  GV+Y +    +   
Sbjct: 15625 NGGSPITGYWLEKREEGSPYWSRVSRAPITKVGLKGVEFNVPRLLEGVKYQFRAMAINAA 15684

Query: 1158  ----DGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWE---RSTTPDITGYRITT 1210
                   +  D  +    + P  PP+   ++    + + ++ W+   +     I GY +  
Sbjct: 15685 GIGPPSEPSDPEVAGDPIFPPGPPSCPEVKDKTKSSI-SLGWKPPAKDGGSPIKGYIVEM 15743

Query: 1211  TP---TNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAV 1267
                  T+ ++ N  ++++   +  C   NL    +Y   V  V +  ES P SDT     
Sbjct: 15744 QEEGTTDWKRVNEPDKLITTCE--CVVPNLKELRKYRFRVKAVNEAGESEP-SDTT--GE 15798

Query: 1268  PPPTDLR-----FTNIGPDTMRVTWA-------------PPPS----IDLTNFLVRYSPV 1305
              P TD++     F +IG     V  A             P P      D          V
Sbjct: 15799 IPATDIQEEPEVFIDIGAQDCLVCKAGSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGV 15858

Query: 1306  KNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTP-LRGRQKTGLDSPTGI 1364
              +  + A+L  + + + +++           S+++  +  + T   R +       P  +
Sbjct: 15859 HDIPEDAQLETAENSSVIIIPECKRSHTGKYSITAKNKAGQKTANCRVKVMDVPGPPKDL 15918

Query: 1365  DFSDITANSFTVHWIAPRAT----ITGYRIRHHPEHFSGRPREDRVPH-SRNSITLTNLT 1419
               SDIT  S  + W  P       I GY I        G+      P     +  + +L 
Sbjct: 15919 KVSDITRGSCRLSWKMPDDDGGDRIKGYVIEKRT--IDGKAWTKVNPDCGSTTFVVPDLL 15976

Query: 1420  PGTEYVVSIVALNGREESPLLIGQQSTVS-------DVPRDLEVVAATPTSLLISWDAPA 1472
                +Y   + A N     P +   Q T +       D P  L++   T  ++ +SW  P 
Sbjct: 15977 SEQQYFFRVRAENRFGIGPPVETIQRTTARDPIYPPDPPIKLKIGLITKNTVHLSWKPP- 16035

Query: 1473  VTVRYYRITYGETGGNSPVQEFTVP-------GSKSTA--------------TISGLKPG 1511
                        +  G SPV  + V        G+K  A              T+  L  G
Sbjct: 16036 -----------KNDGGSPVTHYIVECLAWDPTGTKKEAWRQCNKRDVEELQFTVEDLVEG 16084

Query: 1512  VDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTG 1571
              +Y   V AV   G S  S+             P   Q  D+   SI +K        T 
Sbjct: 16085 GEYEFRVKAVNAAGVSKPSATV----------GPCDCQRPDMPP-SIDLKEFMEVEEGTN 16133

Query: 1572  YRVTTTPKNGPGPT----KTKTAGPDQTEMTIEGLQPTVEYV----VSVYAQNPSGESQP 1623
               +    K  P PT    K     PD  E  +         V      V  Q+   ++  
Sbjct: 16134 VNIVAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDTGL 16193

Query: 1624  LVQTAVTNIDR---------------PKG-LAFTDVDVDSIKIAWESPQ----GQVSRYR 1663
                TAV N+                 P G + F  V  D + ++W  P+     +++ Y 
Sbjct: 16194 YTITAVNNLGTASKEMRLNVLGRPGPPVGPIKFESVSADQMTLSWFPPKDDGGSKITNYV 16253

Query: 1664  VTY--SSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVA-----LHDDMESQPLIG 1716
             +    ++ +  +H    + + +E T  +  L  G EY   ++A     + + ++S+P   
Sbjct: 16254 IEKREANRKTWVHV---SSEPKECTYTIPKLLEGHEYVFRIMAQNKYGIGEPLDSEPETA 16310

Query: 1717  TQSTAIP-APTDLKFTQVTPTSLSAQWTPPNVQ----LTGYRVRVTPKEKTGPM-KEINL 1770
                 ++P AP     + VT  S++  W  P       +TGY + +  K+ T    K +N 
Sbjct: 16311 RNLFSVPGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPVTGYWLEM--KDTTSKRWKRVNR 16368

Query: 1771  APDSS-----SVVVSGLMVATKYEVSVYALKD------TLTSRPAQGVVTTLENVSPPRR 1819
              P  +     S  V+GL+  + Y+  VYA+        +L S PA    T  + ++PP  
Sbjct: 16369 DPIKAMTLGVSYKVTGLIEGSDYQFRVYAINAAGVGPASLPSDPA----TARDPIAPPGP 16424

Query: 1820  A--RVTDATETTITISWRTKTET----ITGFQVDAVPANGQTPIQRTIKPDVRS--YTIT 1871
                +VTD T+++  + W    +     +TG+ V+     G+   ++    +VR     +T
Sbjct: 16425 PFPKVTDWTKSSADLEWSPPLKDGGSKVTGYIVE-YKEEGKEEWEKGKDKEVRGTKLVVT 16483

Query: 1872  GLQPGTDYKIYLYTLNDNARSSPV----VIDASTAIDAPSNLRFLATTPNSLLVSWQPPR 1927
             GL+ G  YK  +  +N      P     VI+    + +P +L+  A+  + ++V      
Sbjct: 16484 GLKEGAFYKFRVRAVNIAGIGEPGEVTDVIEMKDRLVSP-DLQLDASVRDRIVVH-AGGV 16541

Query: 1928  ARITGYIIKYEKPGSPPREVV--PRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPL 1985
              RI  Y+      G PP  V      R    EATI      T      + +KN Q+S   
Sbjct: 16542 IRIIAYV-----SGKPPPTVTWNMNERTLPQEATIE-----TTAISSSMVIKNCQRSHQG 16591

Query: 1986  I----------GRKKTV----------QKTPFVTHPGYDTGNGIQL----PGTSGQQPSV 2021
             +           RKKT+            TPF+ H    T    +L    P   G  P +
Sbjct: 16592 VYSLLAKNEAGERKKTIIVDVLDVPGPVGTPFLAHNL--TNESCKLTWFSPEDDGGSP-I 16648

Query: 2022  GQQMIFEEHGFRRTTPPTTATPIRHRPRPYPPNVGQ----EALSQTTISWAPFQDTSEYI 2077
                +I +    RR   P T T  R          G+       ++ +I   PF +TSE +
Sbjct: 16649 TNYVIEKRESDRRAWTPVTYTVTRQNATVQGLIQGKAYFFRIAAENSIGMGPFVETSEAL 16708

Query: 2078  ISCHPVGTDEEPLQFRVPG-TSTSATLT 2104
             +   P+   E P    V   T  + TLT
Sbjct: 16709 VIREPITVPERPEDLEVKEVTKNTVTLT 16736



 Score = 77.0 bits (188), Expect = 2e-13
 Identities = 270/1352 (19%), Positives = 474/1352 (35%), Gaps = 184/1352 (13%)

Query: 679   GQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFS-PLVATSESVTEITASSFV 737
             G  + I+   H++   +  T  +   P  S TV+ +      P       V+EI   S  
Sbjct: 17271 GSKLEIRNAAHEDGGIYSLTVEN---PAGSKTVSVKVLVLDKPGPPRDLEVSEIRKDSCY 17327

Query: 738   VSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVN----IPDLLPGRKYIVNVYQI 793
             ++W    D        Y + E  D       P +ATS         L  G +Y+  V   
Sbjct: 17328 LTWKEPLDDGGSVITNYVV-ERRDVASAQWSPLSATSKKKSHFAKHLNEGNQYLFRVAAE 17386

Query: 794   SEDGEQSLILSTSQTTAPDA--PPDPTVD----QVDDTSIVVRWSRPQ----APITGYRI 843
             ++ G    + +     A D   PP P  D     VD T + + W++P     +PITGY +
Sbjct: 17387 NQYGRGPFVETPKPIKALDPLHPPGPPKDLHHVDVDKTEVSLVWNKPDRDGGSPITGYLV 17446

Query: 844   VYSPSVEGSSTELNLPETAN-SVTLSDLQPGVQYNITIYA---VEENQESTPVVIQQETT 899
              Y    EG+   +      N    ++ LQ G  Y   + A   V      T + I+ +  
Sbjct: 17447 EYQE--EGTQDWIKFKTVTNLECVVTGLQQGKTYRFRVKAENIVGLGLPDTTIPIECQEK 17504

Query: 900   GTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEH---GQRLPI 956
               P S  +    D++ +E   VK       P + + G  V        G      +   +
Sbjct: 17505 LVPPSVEL----DVKLIEGLVVKAGTTVRFP-AIIRGVPVPTAKWTTDGSEIKTDEHYTV 17559

Query: 957   SRNTFAEVTGLSPGV---TYYFKVFAVSHGRESKPLTAQQTTKLDAPTN----LQFVNET 1009
               + F+ V  +   +   T  +++  VS+   SK + A   T LD P      +  ++ T
Sbjct: 17560 ETDNFSSVLTIKNCLRRDTGEYQI-TVSNAAGSKTV-AVHLTVLDVPGPPTGPINILDVT 17617

Query: 1010  DSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVS 1065
                + + W PP+    + +  Y +    TR+      + G S +K  + +LQ   EY   
Sbjct: 17618 PEHMTISWQPPKDDGGSPVINYIVEKQDTRKDTWGVVSSGSSKTKLKIPHLQKGCEYVFR 17677

Query: 1066  LVAIKGNQESPKATGVFTTLQPGSSIP-----PYNTEVTETTIVITWT------PAPRIG 1114
             + A       P      T  +   S P     P  T++TE    ++WT       +P  G
Sbjct: 17678 VRAENKIGVGPPLDSTPTVAKHKFSPPSPPGKPVVTDITENAATVSWTLPKSDGGSPITG 17737

Query: 1115  FKLGVRPSQGGEAPREVTSDSG-SIVVSGLTPGVEYVYTIQVLR-DGQERDAPIVNKV-- 1170
             + +  R   G       T  +     V+GL  G  Y + +      G  + +P  + +  
Sbjct: 17738 YYMERREVTGKWVRVNKTPIADLKFRVTGLYEGNTYEFRVFAENLAGLSKPSPSSDPIKA 17797

Query: 1171  ---VTPLSPPTNLHLEANPDTGVLTVSWERSTTPD---ITGYRITTTPTNGQQGNSLEEV 1224
                + P  PP N  L+ +       + W +  +     I GY +        Q N + + 
Sbjct: 17798 CRPIKPPGPPINPKLK-DKSRETADLVWTKPLSDGGSPILGYVVECQKPGTAQWNRINKD 17856

Query: 1225  VHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVP--ISDTIIPAV---PPPTDLRFTNIG 1279
                 Q +     L  G EY   +       E  P  +++++I      PP  +L  T   
Sbjct: 17857 ELIRQCAFRVPGLIEGNEYRFRIKAANIVGEGEPRELAESVIAKDILHPPEVELDVTCRD 17916

Query: 1280  PDTMRVTWA----------PPPSIDLTN---FLVRYSPVKNEEDV--AELSISPSDNAVV 1324
               T+RV             P P I  T     LVR   V   +D+   EL I  +  A  
Sbjct: 17917 VITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRA-- 17974

Query: 1325  LTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSP---TGIDFSDITANSFTVHWIAP 1381
                     +Y++S  +     + + +       LD P     +  +++T  + T+ W  P
Sbjct: 17975 -----DHGKYIISAKNSSGHAQGSAI----VNVLDRPGPCQNLKVTNVTKENCTISWENP 18025

Query: 1382  R----ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNG---- 1433
                  + IT + + +   +  G          R  +   NL    EY   + A N     
Sbjct: 18026 LDNGGSEITNFIVEYRKPNQKGWSIVASDVTKR--LIKANLLANNEYYFRVCAENKVGVG 18083

Query: 1434  ---REESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYG---ETGG 1487
                  ++P+L          P +L +     T + + W  P        ++Y       G
Sbjct: 18084 PTIETKTPILAINPIDRPGEPENLHIADKGKTFVYLKWRRPDYDGGSPNLSYHVERRLKG 18143

Query: 1488  NSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASS--KPISINYRTEIDKP 1545
             +   +       K T  +  +   V+  I  + V  + +   S   K   +  + ++ KP
Sbjct: 18144 SDDWERVHKGSIKETHYM--VDRCVENQIYEFRVQTKNEGGESDWVKTEEVVVKEDLQKP 18201

Query: 1546  SQMQVTDVQDNSIS-VKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMT------ 1598
                    V D  +S V  + +   +   R+    +  P P    T   D T++T      
Sbjct: 18202 -------VLDLKLSGVLTVKAGDTI---RLEAGVRGKPFPEVAWTKDKDATDLTRSPRVK 18251

Query: 1599  IEGLQPTVEYVVSVYAQNPSGE--------SQPLVQTAVTNI-DRP---KGLAFTDVDVD 1646
             I+    + ++ ++   ++  G+        +   V  A  N+ D+P   + L   DV  D
Sbjct: 18252 IDTRADSSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATVNVLDKPGPVRNLKIVDVSSD 18311

Query: 1647  SIKIAWESPQG----QVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSV 1702
                + W+ P+     ++  Y +     +  +   + A      T   + L  G+EY   V
Sbjct: 18312 RCTVCWDPPEDDGGCEIQNYILEKCETKRMVWSTYSATVLTPGTTVTR-LIEGNEYIFRV 18370

Query: 1703  -----VALHDDMESQPLIGTQSTAIPA-PTDLKFTQVTPTSLSAQWTPPNVQ----LTGY 1752
                  +      ES+P+I       P  P   + T+V+   ++  W PP       +TGY
Sbjct: 18371 RAENKIGTGPPTESKPVIAKTKYDKPGRPDPPEVTKVSKEEMTVVWNPPEYDGGKSITGY 18430

Query: 1753  RVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKD------TLTSRPAQG 1806
              +    K  T  +     A     + V  L+   +Y+  V A  +      +L SRP   
Sbjct: 18431 FLEKKEKHSTRWVPVNKSAIPERRMKVQNLLPDHEYQFRVKAENEIGIGEPSLPSRPVVA 18490

Query: 1807  VVTTLENVSPPRRARVTDATETTITISWRTKT----ETITGFQV-------DAVPANGQT 1855
                 +E   PP   RV D T+ +IT+ W          I G+ V       DA P  G  
Sbjct: 18491 K-DPIEPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAPIIGYVVEMRPKIADASPDEGWK 18549

Query: 1856  PIQRTIKPDVRSYTITGLQPGTDYKIYLYTLN 1887
                   +   + +T+T L    +Y+  +   N
Sbjct: 18550 RCNAAAQLVRKEFTVTSLDENQEYEFRVCAQN 18581



 Score = 75.9 bits (185), Expect = 4e-13
 Identities = 162/749 (21%), Positives = 272/749 (36%), Gaps = 110/749 (14%)

Query: 1233  TFDNLSPGLEYNVSVYTVKDDKESVPIS-----DTIIPAVPPPTDLRF-------TNI-- 1278
             T ++L  G EY   V  V     S P +     D   P +PP  DL+        TN+  
Sbjct: 16077 TVEDLVEGGEYEFRVKAVNAAGVSKPSATVGPCDCQRPDMPPSIDLKEFMEVEEGTNVNI 16136

Query: 1279  -----GPDTMRVTW--APPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPG 1331
                  G     +TW  APP   D         PV  +  V +L +  +   V+  +    
Sbjct: 16137 VAKIKGVPFPTLTWFKAPPKKPD------NKEPVLYDTHVNKLVVDDTCTLVIPQSRRSD 16190

Query: 1332  TEY--VVSVSSVYEQHESTPLRGRQKTGLDSPTG-IDFSDITANSFTVHWIAPR----AT 1384
             T    + +V+++    +   L    + G   P G I F  ++A+  T+ W  P+    + 
Sbjct: 16191 TGLYTITAVNNLGTASKEMRLNVLGRPG--PPVGPIKFESVSADQMTLSWFPPKDDGGSK 16248

Query: 1385  ITGYRIRHHPE------HFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGR---- 1434
             IT Y I           H S  P+E        + T+  L  G EYV  I+A N      
Sbjct: 16249 ITNYVIEKREANRKTWVHVSSEPKEC-------TYTIPKLLEGHEYVFRIMAQNKYGIGE 16301

Query: 1435  --EESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVT----VRYYRITYGETGGN 1488
               +  P       +V   P    V + T  S+ ++W+ P       V  Y +   +T   
Sbjct: 16302 PLDSEPETARNLFSVPGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPVTGYWLEMKDTTSK 16361

Query: 1489  -------SPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPAS--SKPISINYR 1539
                     P++  T+  S     ++GL  G DY   VYA+   G  PAS  S P +    
Sbjct: 16362 RWKRVNRDPIKAMTLGVSYK---VTGLIEGSDYQFRVYAINAAGVGPASLPSDPATARDP 16418

Query: 1540  TEIDKPSQMQVTDVQDNSISVKWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQT 1595
                  P   +VTD   +S  ++W P      S VTGY V    +      K K      T
Sbjct: 16419 IAPPGPPFPKVTDWTKSSADLEWSPPLKDGGSKVTGYIVEYKEEGKEEWEKGKDKEVRGT 16478

Query: 1596  EMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVD-SIKIAWES 1654
             ++ + GL+    Y   V A N +G  +P   T V  I+    L   D+ +D S++     
Sbjct: 16479 KLVVTGLKEGAFYKFRVRAVNIAGIGEPGEVTDV--IEMKDRLVSPDLQLDASVRDRIVV 16536

Query: 1655  PQGQVSRY----------RVTYSSPEDGI-HELFPAPDGEEDTAELQGLRPGSEYTVSVV 1703
               G V R            VT++  E  +  E          +  ++  +   +   S++
Sbjct: 16537 HAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEATIETTAISSSMVIKNCQRSHQGVYSLL 16596

Query: 1704  ALHDDMESQPLIGTQSTAIPAPTDLKFT--QVTPTSLSAQWTPP----NVQLTGYRVRVT 1757
             A ++  E +  I      +P P    F    +T  S    W  P       +T Y +   
Sbjct: 16597 AKNEAGERKKTIIVDVLDVPGPVGTPFLAHNLTNESCKLTWFSPEDDGGSPITNYVIEKR 16656

Query: 1758  PKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRP---AQGVVTTLENV 1814
               ++      +       +  V GL+    Y   + A ++++   P       +   E +
Sbjct: 16657 ESDRRA-WTPVTYTVTRQNATVQGLIQGKAYFFRI-AAENSIGMGPFVETSEALVIREPI 16714

Query: 1815  SPPRR---ARVTDATETTITISWRTKT----ETITGFQVDAVPANGQTPIQRTIKPDV-- 1865
             + P R     V + T+ T+T++W          I  + +++    G     +    ++  
Sbjct: 16715 TVPERPEDLEVKEVTKNTVTLTWNPPKYDGGSEIINYVLES-RLIGTEKFHKVTNDNLLS 16773

Query: 1866  RSYTITGLQPGTDYKIYLYTLNDNARSSP 1894
             R YT+ GL+ G  Y+  +  +N   +  P
Sbjct: 16774 RKYTVKGLKEGDTYEYRVSAVNIVGQGKP 16802



 Score = 74.3 bits (181), Expect = 1e-12
 Identities = 171/843 (20%), Positives = 321/843 (38%), Gaps = 99/843 (11%)

Query: 1141  SGLTPGVEYVYTIQVLRDG----QERDAPIV---NKVVTPLSPPTNLHLEANPDTGVLTV 1193
             +GL  G EY Y +              +P++   + V  P SPP+   +  +  T  +T+
Sbjct: 26045 TGLREGCEYEYRVYAENAAGLSLPSETSPLIRAEDPVFLP-SPPSKPKIVDSGKT-TITI 26102

Query: 1194  SWERSTTPD---ITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTV 1250
             +W +        ITGY +    ++     +  + +   +   T   L+ G EY   V +V
Sbjct: 26103 AWVKPLFDGGAPITGYTVEYKKSDDTDWKTSIQSLRGTEY--TISGLTTGAEYVFRVKSV 26160

Query: 1251  KDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFL-VRYSPVKN-- 1307
                  S P SD+  P +    +          MR T         T  +  R  PV N  
Sbjct: 26161 NKVGASDP-SDSSDPQIAKEREEEPLFDIDSEMRKTLIVKAGASFTMTVPFRGRPVPNVL 26219

Query: 1308  ----EEDVAELS-ISPSDNAVVLT----NLLPGTEYVVSVSSVYEQHESTPLRGRQKTGL 1358
                 + D+   + +  +D+   LT    N     +Y +++ +V      T +     T  
Sbjct: 26220 WSKPDTDLRTRAYVDTTDSRTSLTIENANRNDSGKYTLTIQNVLSAASLTLVVKVLDTP- 26278

Query: 1359  DSPTGIDFSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRNSIT 1414
               PT I   D+T  S  + W  P     A +  Y I       + +     V ++ N ++
Sbjct: 26279 GPPTNITVQDVTKESAVLSWDVPENDGGAPVKNYHIEKRE---ASKKAWVSVTNNCNRLS 26335

Query: 1415  --LTNLTPGTEYVVSIVALNGREESPLLIGQQSTVS-------DVPRDLEVVAATPTSLL 1465
               +TNL  G  Y   +   +G  E  + I  ++            P  L V + +  S+ 
Sbjct: 26336 YKVTNLQEGAIYYFRV---SGENEFGVGIPAETKEGVKITEKPSPPEKLGVTSISKDSVS 26392

Query: 1466  ISWDAP----AVTVRYYRITYGETGGNSPVQEFTVPGSKSTA-TISGLKPGVDYTITVYA 1520
             ++W  P       + +Y +   E G  + V+      +KST   +SGL+   +Y   V+A
Sbjct: 26393 LTWLKPEHDGGSRIVHYVVEALEKGQKNWVK---CAVAKSTHHVVSGLRENSEYFFRVFA 26449

Query: 1521  VTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKW---LPSSSPVTGYRVTTT 1577
                 G S      + +  + +++ P ++ + +   +++ V+    L    P++G  +   
Sbjct: 26450 ENQAGLSDPRELLLPVLIKEQLEPP-EIDMKNFPSHTVYVRAGSNLKVDIPISGKPLPKV 26508

Query: 1578  PKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVS-------VYAQNPSGESQPLVQTAVT 1630
               +  G    K      TE+T E L   ++  V+       + A N SG ++  +   V 
Sbjct: 26509 TLSRDG-VPLKATMRFNTEITAENLTINLKESVTADAGRYEITAANSSGTTKAFINIVV- 26566

Query: 1631  NIDRPKG----LAFTDVDVDSIKIAWESPQ----GQVSRYRVTYSSPEDGIHELFPAPDG 1682
              +DRP      +  +D+  +S+ + WE P+     QV+ Y +        +     A   
Sbjct: 26567 -LDRPGPPTGPVVISDITEESVTLKWEPPKYDGGSQVTNYILLKRETSTAVWTEVSATVA 26625

Query: 1683  EEDTAELQGLRPGSEYTVSVVA-----LHDDMESQPLIGTQSTAIPAPTDLKF-TQVTPT 1736
                  ++  L  G EY   + A     + D ++S  +        P P    + T VT  
Sbjct: 26626 RT-MMKVMKLTTGEEYQFRIKAENRFGISDHIDSACVTVKLPYTTPGPPSTPWVTNVTRE 26684

Query: 1737  SLSAQWTPP----NVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSV 1792
             S++  W  P       + GY + +  +      K   L   ++   V+ +     YE  V
Sbjct: 26685 SITVGWHEPVSNGGSAVVGYHLEMKDRNSILWQKANKLVIRTTHFKVTTISAGLIYEFRV 26744

Query: 1793  YALKDTLTSRPAQGV--VTTLENVSPPRRARVTDATETTITISWRTKT----ETITGFQV 1846
             YA       +P+     V  ++   PPR  R+TD ++ ++++SW+         ITG+ V
Sbjct: 26745 YAENAAGVGKPSHPSEPVLAIDACEPPRNVRITDISKNSVSLSWQQPAFDGGSKITGYIV 26804

Query: 1847  DA--VPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLN--DNARSSPVVIDASTA 1902
             +   +P    T    T   + + + I+GL   + Y+  ++  N   +  +   V+   T 
Sbjct: 26805 ERRDLPDGRWTKASFTNVTETQ-FIISGLTQNSQYEFRVFARNAVGSISNPSEVVGPITC 26863

Query: 1903  IDA 1905
             ID+
Sbjct: 26864 IDS 26866



 Score = 65.5 bits (158), Expect = 6e-10
 Identities = 290/1521 (19%), Positives = 542/1521 (35%), Gaps = 205/1521 (13%)

Query: 628   IQWNAPQ---PSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISI 684
             + W+AP     S ++ + +  + +NS+   K  T P     Y   GL  G+ Y+ ++ + 
Sbjct: 27775 LTWDAPVYDGGSEVTGFHVEKKERNSILWQKVNTSPISGREYRATGLVEGLDYQFRVYAE 27834

Query: 685   QQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSAS 744
                G              S+P   +  T   +P  P    +    ++T  +  + W    
Sbjct: 27835 NSAG-------------LSSPSDPSKFTLAVSPVDP--PGTPDYIDVTRETITLKWNPPL 27879

Query: 745   DTVSGFRVEYELSEEGDEPQYLDLPSTATS---VNIPDLLPGRKYIVNVYQ------ISE 795
                    V Y + +     +++    T  S     +  L PG +Y   +        IS 
Sbjct: 27880 RDGGSKIVGYSIEKRQGNERWVRCNFTDVSECQYTVTGLSPGDRYEFRIIARNAVGTISP 27939

Query: 796   DGEQSLILSTSQTTAPDAPPDPTVD---QVDDTSIVVRWS--RPQAPITGYRIV----YS 846
               + S I+ T     P     P V+   +  D  I+      R +A + G  +     + 
Sbjct: 27940 PSQSSGIIMTRDENVP-----PIVEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVTWFK 27994

Query: 847   PSVE-GSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQES--TPVVIQQETTGTPR 903
               VE      + + +   S +L  ++   + +  +Y VE    S      I+ +   TP 
Sbjct: 27995 DGVEIEKRMNMEITDVLGSTSLF-VRDATRDHRGVYTVEAKNASGSAKAEIKVKVQDTPG 28053

Query: 904   SDTVPSPRDLQFVEVTDVKVTIMWTPPES----AVTGYRVDVIPVNLPGEHGQRLPISRN 959
                 P    ++F  +T  K+T+ W  P +     +T Y ++    +              
Sbjct: 28054 KVVGP----IRFTNITGEKMTLWWDAPLNDGCAPITHYIIEKRETSRLAWALIEDKCEAQ 28109

Query: 960   TFAEVTGLSPGVTYYFKVFAVSH---GR--ESKPLTAQ-QTTKLDAPTNLQFVNETDSTV 1013
             ++  +  L  G  Y F+V AV+    GR  +S P+ AQ Q T  DAP   +  N T +++
Sbjct: 28110 SYTAIK-LINGNEYQFRVSAVNKFGVGRPLDSDPVVAQIQYTVPDAPGIPEPSNITGNSI 28168

Query: 1014  LVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRN-------LQPASEYTVSL 1066
              + W  P +   G  +   +  R + +       +SK P+         L   +EY   +
Sbjct: 28169 TLTWARPESD-GGSEIQQYILERREKKSTRWVKVISKRPISETRFKVTGLTEGNEYEFHV 28227

Query: 1067  VAIKGNQESPKATGVFTTLQ-------PGSSIPPYNTEVTETTIVITWTPA------PRI 1113
             +A       P A+G+   ++       PG       T+ ++TT+ + W+          I
Sbjct: 28228 MAENAAGVGP-ASGISRLIKCREPVNPPGPPTVVKVTDTSKTTVSLEWSKPVFDGGMEII 28286

Query: 1114  GFKLGVRPSQGGEAPREVTSDS---GSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKV 1170
             G+ + +  +  G+   +V +++       V+ L  G EY + +  +    + D+  V   
Sbjct: 28287 GYIIEMCKADLGDW-HKVNAEACVKTRYTVTDLQAGEEYKFRVSAINGAGKGDSCEVTGT 28345

Query: 1171  VTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPT----NGQQGNSLEEVVH 1226
             +  +   T   L+ + +     V    ++      Y+   TPT          SL   +H
Sbjct: 28346 IKAVDRLTAPELDIDANFKQTHVVRAGASIRLFIAYQGRPTPTAVWSKPDSNLSLRADIH 28405

Query: 1227  ADQSSCTFD----NLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRFTNIGPDT 1282
                S  T      N +   +Y ++V      K S+  +  ++    PP  + F ++   +
Sbjct: 28406 TTDSFSTLTVENCNRNDAGKYTLTVENNSGSK-SITFTVKVLDTPGPPGPITFKDVTRGS 28464

Query: 1283  MRVTWAPPPSIDLTNFLVRYSPVKNEEDVAE---LSISPSDNAVVLTNLLPGTEYVVSVS 1339
               + W   P +D    +  Y   K E        +S   +     + +L  G  Y   VS
Sbjct: 28465 ATLMW-DAPLLDGGARIHHYVVEKREASRRSWQVISEKCTRQIFKVNDLAEGVPYYFRVS 28523

Query: 1340  SVYEQHESTPLRGRQKTGLDS----PTGIDFSDITANSFTVHWIAPR----ATITGYRIR 1391
             +V E     P    +          P  +D  D + +S  + W+ P     + ITGY + 
Sbjct: 28524 AVNEYGVGEPYEMPEPIVATEQPAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRITGYLLE 28583

Query: 1392  HHPEHFSGRPREDRVPHSRN-SITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDV 1450
                +   G        H++  + T+  L   TEY   + A N    S       S +   
Sbjct: 28584 MRQK---GSDFWVEAGHTKQLTFTVERLVEKTEYEFRVKAKNDAGYSEPREAFSSVIIKE 28640

Query: 1451  PR-----DLEVV--------AATPTSL---LISWDAPAVTVRYYRITYGETGGNSPVQEF 1494
             P+     DL  +        A +P ++   +    AP VT +   +   ET   S     
Sbjct: 28641 PQIEPTADLTGITNQLITCKAGSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVS----I 28696

Query: 1495  TVPGSKSTATISGLKPGVD--YTITVYAVTGRGDSPASSKPISINYRTEIDKPSQM---- 1548
             T    ++T T+     G    Y +T+       ++ A  K  S+     I +P  +    
Sbjct: 28697 TTTKDRTTLTVKDSMRGDSGRYFLTL-------ENTAGVKTFSVTV-VVIGRPGPVTGPI 28748

Query: 1549  QVTDVQDNSISVKWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQP 1604
             +V+ V   S  + W        + +T Y +    ++G    +   +   +T++ +  L  
Sbjct: 28749 EVSSVSAESCVLSWGEPKDGGGTEITNY-IVEKRESGTTAWQLVNSSVKRTQIKVTHLTK 28807

Query: 1605  TVEYVVSVYAQNPSGESQPLVQTAV------TNIDRPKGLAFTDVDVDSIKIAWESPQGQ 1658
              +EY   V ++N  G S+PL    +           P       V  +++ I WE P   
Sbjct: 28808 YMEYSFRVSSENRFGVSKPLESAPIIAEHPFVPPSAPTRPEVYHVSANAMSIRWEEPYHD 28867

Query: 1659  VSRYRVTYSSPEDGIHELFPAPDGE----EDTAELQGLRPGSEYTVSVVALH------DD 1708
                  + Y   +   + +    + +    E   ++ GL  G EY     AL+        
Sbjct: 28868 GGSKIIGYWVEKKERNTILWVKENKVPCLECNYKVTGLVEGLEYQFRTYALNAAGVSKAS 28927

Query: 1709  MESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPP----NVQLTGYRVRVTPKEKTGP 1764
               S+P++      + AP   + T VT +++S  W+ P      ++ GY +   P  + G 
Sbjct: 28928 EASRPIMA--QNPVDAPGRPEVTDVTRSTVSLIWSAPAYDGGSKVVGYIIERKPVSEVGD 28985

Query: 1765  ---MKEINLAPDSSSVVVSGLMVATKYEVSVYALKDT-LTSRPAQ--GVVTTLENVSPPR 1818
                +K        +   V+ L     YE  V A     + S+ ++  G VT  +  +PP+
Sbjct: 28986 GRWLKCNYTIVSDNFFTVTALSEGDTYEFRVLAKNAAGVISKGSESTGPVTCRDEYAPPK 29045

Query: 1819  RARVTDATETTITISWRTKTETITGFQVDAVP------ANGQTPIQRTIKPDV-----RS 1867
                  DA      ++ R  ++ +    V   P        G   +    K  +     R+
Sbjct: 29046 AE--LDARLHGDLVTIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRA 29103

Query: 1868  YTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAP---SNLRFLATTPNSLLVSWQ 1924
               +      +D   Y  T+  NA  +  V      +D+P     L     T     ++W 
Sbjct: 29104 TAVIKFCDRSDSGKYTLTVK-NASGTKAVSVMVKVLDSPGPCGKLTVSRVTQEKCTLAWS 29162

Query: 1925  PPR----ARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKN-- 1978
              P+    A IT YI++  +       +V    P ++   +T L    EY   V A+    
Sbjct: 29163 LPQEDGGAEITHYIVERRETSRLNWVIVEGECPTLS-YVVTRLIKNNEYIFRVRAVNKYG 29221

Query: 1979  ---NQKSEPLIGRKKTVQKTP 1996
                  +SEP++ R      +P
Sbjct: 29222 PGVPVESEPIVARNSFTIPSP 29242



 Score = 64.3 bits (155), Expect = 1e-09
 Identities = 115/519 (22%), Positives = 183/519 (35%), Gaps = 81/519 (15%)

Query: 1542  IDKPS---QMQVTDVQDNSISVKWLPSSSP----VTGYRVTTTP-KNGPGPTKTKTAGPD 1593
             +DKP     +++ DV  +  +V W P        +  Y +     K     T + T    
Sbjct: 18294 LDKPGPVRNLKIVDVSSDRCTVCWDPPEDDGGCEIQNYILEKCETKRMVWSTYSATVLTP 18353

Query: 1594  QTEMT--IEGLQPTVEYVVSVYAQN-----PSGESQPLV-QTAVTNIDRPKGLAFTDVDV 1645
              T +T  IEG     EY+  V A+N     P  ES+P++ +T      RP     T V  
Sbjct: 18354 GTTVTRLIEGN----EYIFRVRAENKIGTGPPTESKPVIAKTKYDKPGRPDPPEVTKVSK 18409

Query: 1646  DSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGE----EDTAELQGLRPGSEYTVS 1701
             + + + W  P+    +    Y   +   H     P  +    E   ++Q L P  EY   
Sbjct: 18410 EEMTVVWNPPEYDGGKSITGYFLEKKEKHSTRWVPVNKSAIPERRMKVQNLLPDHEYQFR 18469

Query: 1702  VVALHD------DMESQPLIGTQSTAIPAP-TDLKFTQVTPTSLSAQWTPP----NVQLT 1750
             V A ++       + S+P++       P P T+ +    T  S++  W  P       + 
Sbjct: 18470 VKAENEIGIGEPSLPSRPVVAKDPIEPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAPII 18529

Query: 1751  GYRVRVTPKEKTGP----MKEINLAPD--SSSVVVSGLMVATKYEVSVYALKDTLTSRPA 1804
             GY V + PK          K  N A         V+ L    +YE  V A       RPA
Sbjct: 18530 GYVVEMRPKIADASPDEGWKRCNAAAQLVRKEFTVTSLDENQEYEFRVCAQNQVGIGRPA 18589

Query: 1805  Q--GVVTTLENVSPPRRARVTDATETTIT-------------------ISWRTK--TETI 1841
             +    +   E + PP         +  I                    ++WR       +
Sbjct: 18590 ELKEAIKPKEILEPPEIDLDASMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVV 18649

Query: 1842  TGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDAST 1901
                QVD V       I  + + D   Y++T + P  +  +++     N R    V+D   
Sbjct: 18650 RKGQVDLVDTMAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFV-----NVR----VLDTPG 18700

Query: 1902  AIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREVVPRPRPGVTE 1957
              +   S+L+    T  S  VSW PP     +++T YI++  +        V  P    T 
Sbjct: 18701 PV---SDLKVSDVTKTSCHVSWAPPENDGGSQVTHYIVEKREADRKTWSTVT-PEVKKTS 18756

Query: 1958  ATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQKTP 1996
               +T L PG EY   V A+       P    K  +   P
Sbjct: 18757 FHVTNLVPGNEYYFRVTAVNEYGPGVPTDVPKPVLASDP 18795



 Score = 62.4 bits (150), Expect = 5e-09
 Identities = 182/847 (21%), Positives = 298/847 (35%), Gaps = 156/847 (18%)

Query: 1263  IIPAVPPPTDLRFTNIGPDTMRVTWAPPPS---IDLTNFLVRYSPVKNEEDVAELSISPS 1319
             +I    P  +L  T      + + W  P +     +  ++V    +K +  V     + S
Sbjct: 13086 VIDVPGPVRNLEVTETFDGEVSLAWEEPLTDGGSKIIGYVVERRDIKRKTWVLATDRAES 13145

Query: 1320  DNAVVLTNLLPGTEYVVSVSS-----VYEQHES-TPLRGRQKTGLDSPT-GIDFSDITAN 1372
                 V      G EY+  VS+       E  E+  P+  R K  +  P   +  +D+   
Sbjct: 13146 CEFTVTGLQKGGVEYLFRVSARNRVGTGEPVETDNPVEARSKYDVPGPPLNVTITDVNRF 13205

Query: 1373  SFTVHWIAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSI 1428
               ++ W  P     A IT Y I    +          V     S T+T++  G EY   +
Sbjct: 13206 GVSLTWEPPEYDGGAEITNYVIELRDKTSIRWDTAMTVRAEDLSATVTDVVEGQEYSFRV 13265

Query: 1429  VALNGREESPLLIGQQSTVSDV------------PRDLEVVAATPTSLLISWDAP----A 1472
                  R ++ + +G+ S  +              P +L     T +S+ + W+ P     
Sbjct: 13266 -----RAQNRIGVGKPSAATPFVKVADPIERPSPPVNLTSSDQTQSSVQLKWEPPLKDGG 13320

Query: 1473  VTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSK 1532
               +  Y I   E G ++ ++       + T  ++GL+ G  Y   V A    G S  S  
Sbjct: 13321 SPILGYIIERCEEGKDNWIRCNMKLVPELTYKVTGLEKGNKYLYRVSAENKAGVSDPSEI 13380

Query: 1533  PISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSS--PVTGYRVTTTPKNGPGPTKTKTA 1590
                +       +P+ M ++  +D    +   P +   P TGY         P PT T   
Sbjct: 13381 LGPLTADDAFVEPT-MDLSAFKDGLEVIVPNPITILVPSTGY---------PRPTATWCF 13430

Query: 1591  GPDQTE----MTIEGLQPTVEYVVSVYAQNPSG----ESQPLVQTAVTNID--------R 1634
             G    E    + ++ L    E V+S   ++  G    + +  V+T    ID         
Sbjct: 13431 GDKVLETGDRVKMKTLSAYAELVISPSERSDKGIYTLKLENRVKTISGEIDVNVIARPSA 13490

Query: 1635  PKGLAFTDVDVDSIKIAWESPQ----GQVSRY--------RVTYSSPEDGIHEL-FPAPD 1681
             PK L F D+  DS+ + WE P       ++ Y        R T++   D + +L F  PD
Sbjct: 13491 PKELKFGDITKDSVHLTWEPPDDDGGSPLTGYVVEKREVSRKTWTKVMDFVTDLEFTVPD 13550

Query: 1682  GEEDTAELQGLRPGSEYTVSVVALHDDMESQPL-------IGTQSTAIPAPTDLKFTQVT 1734
                       L  G EY   V A +     +P        + T +T    P ++K+   T
Sbjct: 13551 ----------LVQGKEYLFKVCARNKCGPGEPAYVDEPVNMSTPATVPDPPENVKWRDRT 13600

Query: 1735  PTSLSAQWTPP----NVQLTGYRVRVTPKEKTGPMKEINLAPD--SSSVVVSGLMVATKY 1788
               S+   W PP      ++ GY V   P+   G  K +        + + V+GL     Y
Sbjct: 13601 ANSIFLTWDPPKNDGGSRIKGYIVERCPR---GSDKWVACGEPVAETKMEVTGLEEGKWY 13657

Query: 1789  EVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETT-----------ITISWRTK 1837
                V AL     S+P++          P    +  D  E             +T+   TK
Sbjct: 13658 AYRVKALNRQGASKPSR----------PTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTK 13707

Query: 1838  TE---TITGFQVDAVPANGQTPIQRTIKPDVR----------SYTITGLQPGTDYKIYLY 1884
              E   T+TG      P    T     +K D R          + TI   +        + 
Sbjct: 13708 IELPATVTG---KPEPKITWTKADMILKQDKRITIENVPKKSTVTIVDSKRSDTGTYIIE 13764

Query: 1885  TLNDNARSSPVV-IDASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEK 1939
              +N   R++ VV ++       P+       T  S L++W PPR    ++IT Y+++   
Sbjct: 13765 AVNVCGRATAVVEVNVLDKPGPPAAFDITDVTNESCLLTWNPPRDDGGSKITNYVVERRA 13824

Query: 1940  PGSPPREVVPRPRPGV--TEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQKTPF 1997
               S   EV  +    V  T    T L P  EY   V A       E + G  + VQ +P 
Sbjct: 13825 TDS---EVWHKLSSTVKDTNFKATKLIPNKEYIFRVAA-------ENMYGVGEPVQASPI 13874

Query: 1998  VTHPGYD 2004
                  +D
Sbjct: 13875 TAKYQFD 13881



 Score = 52.8 bits (125), Expect = 4e-06
 Identities = 80/336 (23%), Positives = 120/336 (35%), Gaps = 46/336 (13%)

Query: 602   LQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQP---SHISKYILRWRPKN-SVGRWKEA 657
             ++ Y   S P  + +T+  ++  S  + W+AP     S I+ Y++  R  +     W+E 
Sbjct: 15492 VEVYDRPSPPRNLAVTDIKAE--SCYLTWDAPLDNGGSEITHYVIDKRDASRKKAEWEEV 15549

Query: 658   TIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTP 717
             T       Y I  L P   YE ++ ++ +YG  +  + D         V  +       P
Sbjct: 15550 TNTAVEKRYGIWKLIPNGQYEFRVRAVNKYGISDECKSD-------KVVIQDPYRLPGPP 15602

Query: 718   FSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTA----- 772
               P V         T  S +VSW    D        Y L +  +   Y    S A     
Sbjct: 15603 GKPKVLAR------TKGSMLVSWTPPLDNGGSPITGYWLEKREEGSPYWSRVSRAPITKV 15656

Query: 773   ----TSVNIPDLLPGRKY-----IVNVYQISEDGEQSLILSTSQTTAPDAPPD-PTVDQV 822
                    N+P LL G KY      +N   I    E S          P  PP  P V   
Sbjct: 15657 GLKGVEFNVPRLLEGVKYQFRAMAINAAGIGPPSEPSDPEVAGDPIFPPGPPSCPEVKDK 15716

Query: 823   DDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPE---TANSVTLSDLQPGVQ 875
               +SI + W  P     +PI GY +            +N P+   T     + +L+   +
Sbjct: 15717 TKSSISLGWKPPAKDGGSPIKGYIVEMQEEGTTDWKRVNEPDKLITTCECVVPNLKELRK 15776

Query: 876   YNITIYAVEENQESTPVVIQQETTG-TPRSDTVPSP 910
             Y   + AV E  ES P     +TTG  P +D    P
Sbjct: 15777 YRFRVKAVNEAGESEP----SDTTGEIPATDIQEEP 15808



 Score = 43.9 bits (102), Expect = 0.002
 Identities = 50/204 (24%), Positives = 83/204 (40%), Gaps = 22/204 (10%)

Query: 717   PFSPLVATSESVTEITASSFVVSWVSASDT----VSGFRVEYELSEEGDEPQYLDLPSTA 772
             P  P+V     +  +  +S V+SW   +D     ++ + VE   ++EG E Q +    + 
Sbjct: 30726 PTGPIV-----IEALLKNSAVISWKPPADDGGSWITNYVVEKCEAKEGAEWQLVSSAISV 30780

Query: 773   TSVNIPDLLPGRKYIV-----NVYQISEDGE-QSLILSTSQTTAPDAPPDPTVDQVDDTS 826
             T+  I +L     Y       N + IS+  E  S+++  S    P AP  PT+  V   S
Sbjct: 30781 TTCRIVNLTENAGYYFRVSAQNTFGISDPLEVSSVVIIKSPFEKPGAPGKPTITAVTKDS 30840

Query: 827   IVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSV-TLSDLQPGVQYNITIY 881
              VV W  P     A I  Y +      +     +   E   +V ++ +L  G++Y   + 
Sbjct: 30841 CVVAWKPPASDGGAKIRNYYLEKREKKQNKWISVTTEEIRETVFSVKNLIEGLEYEFRVK 30900

Query: 882   AVEENQESTPVVIQQETTGTPRSD 905
                   ES    I +    TP+SD
Sbjct: 30901 CENLGGESEWSEISEPI--TPKSD 30922



 Score = 41.2 bits (95), Expect = 0.012
 Identities = 92/413 (22%), Positives = 157/413 (38%), Gaps = 51/413 (12%)

Query: 1285  VTWAPPPSID---LTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSV 1341
             ++W PP       +TN++V     K   +   +S + S     + NL     Y   VS+ 
Sbjct: 30742 ISWKPPADDGGSWITNYVVEKCEAKEGAEWQLVSSAISVTTCRIVNLTENAGYYFRVSAQ 30801

Query: 1342  YEQHESTPLRGRQKTGLDSPTGID-------FSDITANSFTVHWIAPRATITGYRIRHHP 1394
                  S PL       + SP            + +T +S  V W  P A+  G +IR++ 
Sbjct: 30802 NTFGISDPLEVSSVVIIKSPFEKPGAPGKPTITAVTKDSCVVAW-KPPASDGGAKIRNYY 30860

Query: 1395  EHFSGRPREDRVPHSRNSITLT-----NLTPGTEYVVSIVA--LNGREESPLLIGQQSTV 1447
                  + +   +  +   I  T     NL  G EY   +    L G  E   +    +  
Sbjct: 30861 LEKREKKQNKWISVTTEEIRETVFSVKNLIEGLEYEFRVKCENLGGESEWSEISEPITPK 30920

Query: 1448  SDVP----------RDLEVVAATPTSLLISWDA-PAVTVRYYRITYGET----GGNSPVQ 1492
             SDVP          R+L V   +  +L+      P   V++YR   G+     G    +Q
Sbjct: 30921 SDVPIQAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYR--QGKEIIADGLKYRIQ 30978

Query: 1493  EFTVPGSKSTATISGLKPGVDYTITVYAV--TGRGDSPASSKPISINYRTEIDKPSQMQ- 1549
             EF   G      I+ +    D   TVY V  T +G S + +  + +    +I  P  ++ 
Sbjct: 30979 EFK--GGYHQLIIASV---TDDDATVYQVRATNQGGSVSGTASLEVEVPAKIHLPKTLEG 31033

Query: 1550  ---VTDVQDNSISVKWLPSSS---PVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQ 1603
                V  ++   +S+K +P S    PV  ++      +  G  +        + +   G++
Sbjct: 31034 MGAVHALRGEVVSIK-IPFSGKPDPVITWQKGQDLIDNNGHYQVIVTRSFTSLVFPNGVE 31092

Query: 1604  PTVEYVVSVYAQNPSGESQPLVQTAVTNI-DRPKGLAFTDVDVDSIKIAWESP 1655
                     V A+N  G  Q  V+  V ++ D P+G+  +DV  DS+ + W  P
Sbjct: 31093 RKDAGFYVVCAKNRFGIDQKTVELDVADVPDPPRGVKVSDVSRDSVNLTWTEP 31145



 Score = 37.7 bits (86), Expect = 0.13
 Identities = 36/131 (27%), Positives = 53/131 (40%), Gaps = 8/131 (6%)

Query: 894   IQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPVNLPGE 949
             I Q+T     +D    PR ++  +V+   V + WT P     S +T Y V+        E
Sbjct: 31109 IDQKTVELDVADVPDPPRGVKVSDVSRDSVNLTWTEPASDGGSKITNYIVEKCATT--AE 31166

Query: 950   HGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQ--TTKLDAPTNLQFVN 1007
                R+  +R T   V  L    +Y F+V A +    SKP    +   TK D    + +  
Sbjct: 31167 RWLRVGQARETRYTVINLFGKTSYQFRVIAENKFGLSKPSEPSEPTITKEDKTRAMNYDE 31226

Query: 1008  ETDSTVLVRWT 1018
             E D T  V  T
Sbjct: 31227 EVDETREVSMT 31237



 Score = 35.0 bits (79), Expect = 0.86
 Identities = 38/169 (22%), Positives = 71/169 (42%), Gaps = 17/169 (10%)

Query: 1519  YAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWL-PSS---SPVTGYRV 1574
             Y V  +       K + ++     D P  ++V+DV  +S+++ W  P+S   S +T Y V
Sbjct: 31099 YVVCAKNRFGIDQKTVELDVADVPDPPRGVKVSDVSRDSVNLTWTEPASDGGSKITNYIV 31158

Query: 1575  TTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPL--VQTAVTNI 1632
                        +   A   +T  T+  L     Y   V A+N  G S+P    +  +T  
Sbjct: 31159 EKCATTAERWLRVGQA--RETRYTVINLFGKTSYQFRVIAENKFGLSKPSEPSEPTITKE 31216

Query: 1633  DRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPD 1681
             D+ + + + D +VD  +        +VS  + ++SS ++   +   A D
Sbjct: 31217 DKTRAMNY-DEEVDETR--------EVSMTKASHSSTKELYEKYMIAED 31256


>gi|110349717 titin isoform novex-2 [Homo sapiens]
          Length = 27118

 Score =  154 bits (388), Expect = 1e-36
 Identities = 299/1365 (21%), Positives = 509/1365 (37%), Gaps = 169/1365 (12%)

Query: 590   YGRGIGEWHCQPLQTYPSSSGPVEVFITETPSQPNSHPI-QWNAPQP---SHISKYILRW 645
             YG G+     +P+    S + P    I E       H I QW  P+    + IS Y++  
Sbjct: 22915 YGPGVPV-ESEPIVARNSFTIPSPPGIPEEVGTGKEHIIIQWTKPESDGGNEISNYLVDK 22973

Query: 646   RPKNSVGRWKEATIPGHLNSYTIK--GLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTS 703
             R K S+ RW        +    +K   L  G  Y+ ++ ++   G+ E +          
Sbjct: 22974 REKKSL-RWTRVNKDYVVYDTRLKVTSLMEGCDYQFRVTAVNAAGNSEPSE--------- 23023

Query: 704   TPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELS-EEGDE 762
                 SN ++     ++P   ++  V + T  S  ++W           V Y L  +E D 
Sbjct: 23024 ---ASNFISCREPSYTPGPPSAPRVVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDT 23080

Query: 763   PQYLDLPSTATSVN----IPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPT 818
              Q+  + + AT  N    +PDL  G+KY   V  ++  G      S ++    +    P 
Sbjct: 23081 DQWYRVHTNATIRNTEFTVPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEIPD 23140

Query: 819   VDQVDDT--SIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLP-----ETANSVTLSDLQ 871
             ++  DD   ++ +R       +        P +  S   ++L      +T  S +L  + 
Sbjct: 23141 LELADDLKKTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAIIDTTESYSLLIVD 23200

Query: 872   PGVQYNITIYAVE-ENQE----STPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIM 926
                +Y+   Y +E ENQ     +T +V   +T G       P P  ++  EV+   VTI 
Sbjct: 23201 KVNRYDAGKYTIEAENQSGKKSATVLVKVYDTPG-------PCP-SVKVKEVSRDSVTIT 23252

Query: 927   WTPPE----SAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSH 982
             W  P     + V  Y V+     +          S+ T   ++GL  G  YYF+V   + 
Sbjct: 23253 WEIPTIDGGAPVNNYIVEKREAAMRAFKTVTTKCSK-TLYRISGLVEGTMYYFRVLPENI 23311

Query: 983   GRESKPLTAQQTTKLD----APTNLQFVNETDSTVLVRWTPPR----AQITGYRLTVGLT 1034
                 +P        +      P  L+ V+ T STV + W  P     +++TGY L     
Sbjct: 23312 YGIGEPCETSDAVLVSEVPLVPAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEA--C 23369

Query: 1035  RRGQPRQYNV---GPSVSKYPLRNLQPASEYTVSLVAI--KGNQESPKATGVFTTLQPGS 1089
             + G  R   V    P+V ++ + +L    +Y   + A   KG  E P+ T    T+Q   
Sbjct: 23370 KAGTERWMKVVTLKPTVLEHTVTSLNEGEQYLFRIRAQNEKGVSE-PRETVTAVTVQDLR 23428

Query: 1090  SIPPYNTEV-------------TETTIVITWTPAPRIG-FKLGVRPSQGGEAPREVTSDS 1135
              +P  +                 E  I I   P P    F  G +  +      E  +  
Sbjct: 23429 VLPTIDLSTMPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKV 23488

Query: 1136  GSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSW 1195
               + +   T      YT+++          I   ++    PPT        D   +T+SW
Sbjct: 23489 AKLTIRETTIRDTGEYTLELKNVTGTTSETIKVIILDKPGPPTGPIKIDEIDATSITISW 23548

Query: 1196  ERSTTPD---ITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSV----- 1247
             E         ++GY +     +      + E V   +S+  F  L+ G EY   V     
Sbjct: 23549 EPPELDGGAPLSGYVVEQRDAHRPGWLPVSESV--TRSTFKFTRLTEGNEYVFRVAATNR 23606

Query: 1248  YTVKDDKESVPISDTIIPAVP-PPTDLRFTNIGPDTMRVTWAPPPS---IDLTNFLVRYS 1303
             + +    +S  I       +P PP  L+  ++  D M +TW PP       +T ++V   
Sbjct: 23607 FGIGSYLQSEVIECRSSIRIPGPPETLQIFDVSRDGMTLTWYPPEDDGGSQVTGYIVERK 23666

Query: 1304  PVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLR-GRQKTGLD--- 1359
              V+ +  V    +  +      T L  G EY   V+++  +    P R  +    +D   
Sbjct: 23667 EVRADRWVRVNKVPVTMTRYRSTGLTEGLEYEHRVTAINARGSGKPSRPSKPIVAMDPIA 23726

Query: 1360  ---SPTGIDFSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRNS 1412
                 P     +D T  S ++ W  P     + +TGY I           + +  P     
Sbjct: 23727 PPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTKCNTTPTKIRE 23786

Query: 1413  ITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAAT--PTSLLISWDA 1470
              TLT+L  G EY   ++A N         G     ++VP  ++V      P   L     
Sbjct: 23787 YTLTHLPQGAEYRFRVLACNA--------GGPGEPAEVPGTVKVTEMLEYPDYELDERYQ 23838

Query: 1471  PAVTVRY---YRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDS 1527
               + VR     R+T    G   P+ ++T  G +  +  + +     +T  V     RGDS
Sbjct: 23839 EGIFVRQGGVIRLTIPIKGKPFPICKWTKEG-QDISKRAMIATSETHTELVIKEADRGDS 23897

Query: 1528  ---------PASSKPISINYRTEIDKPSQ----MQVTDVQDNSISVKWLPSS----SPVT 1570
                          K + I  R  I  P+     ++  D+Q  S+ V W P +    + + 
Sbjct: 23898 GTYDLVLENKCGKKAVYIKVRV-IGSPNSPEGPLEYDDIQVRSVRVSWRPPADDGGADIL 23956

Query: 1571  GYRVTT--TPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQ-- 1626
             GY +     PK       ++  G   T + ++GL+  VEY   V A+N  G S+PL    
Sbjct: 23957 GYILERREVPKAAWYTIDSRVRG---TSLVVKGLKENVEYHFRVSAENQFGISKPLKSEE 24013

Query: 1627  --TAVTNIDRPKGLA----FTDVDVDSIKIAWESPQGQ-VSRYRVTYSSPEDGIHELFPA 1679
               T  T ++ P+  +      DV   S+ ++W  P+    SR    Y   ++   + +  
Sbjct: 24014 PVTPKTPLNPPEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRVTGYYIERKETSTDKWVR 24073

Query: 1680  PDGEEDTAEL---QGLRPGSEYTVSVVALHD------DMESQPLIGTQSTAIPA-PTDLK 1729
              +  + T  +    GL P +EY   ++A +D         S+P++       P+ P +L+
Sbjct: 24074 HNKTQITTTMYTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCKDPFDKPSQPGELE 24133

Query: 1730  FTQVTPTSLSAQWTPPNV----QLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVA 1785
                ++  S++ QW  P      ++ GY V       +   K            + GL+ A
Sbjct: 24134 ILSISKDSVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERIKDKQFTIGGLLEA 24193

Query: 1786  TKYEVSVYALKDTLTSRP---AQGVVTTL-ENVSPPRRARVTDAT 1826
             T+YE  V+A  +T  SRP   A  + T L    +P  R  + D T
Sbjct: 24194 TEYEFRVFAENETGLSRPRRTAMSIKTKLTSGEAPGIRKEMKDVT 24238



 Score =  148 bits (373), Expect = 7e-35
 Identities = 289/1429 (20%), Positives = 524/1429 (36%), Gaps = 170/1429 (11%)

Query: 696   DFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYE 755
             D+T T+ ++  + +          P    S  + ++ +   ++SW    +        Y 
Sbjct: 13060 DYTITAENSSGSKSATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYI 13119

Query: 756   LSE-EGDEPQYLDLPSTA--TSVNIPDLLPGRKY-----IVNVYQISEDGEQSLILSTSQ 807
             + + E   P +  + +T   TS ++  L+ G +Y       N Y + +       ++ + 
Sbjct: 13120 VDKRETSRPNWAQVSATVPITSCSVEKLIEGHEYQFRICAENKYGVGDPVFTEPAIAKNP 13179

Query: 808   TTAPDAPPDPTVDQVDDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNL-PETA 862
                P     P +  +    + V W  P     +PITGY +    +   + T++N  P   
Sbjct: 13180 YDPPGRCDPPVISNITKDHMTVSWKPPADDGGSPITGYLLEKRETQAVNWTKVNRKPIIE 13239

Query: 863   NSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVK 922
              ++  + LQ G +Y   + A+ +     P    +             P   +  + T   
Sbjct: 13240 RTLKATGLQEGTEYEFRVTAINKAGPGKPSDASKAAYARDPQYPPGPPAFPKVYDTTRSS 13299

Query: 923   VTIMWTPPE----SAVTGYRVDVIPVNLPGEHGQRLPIS-RNTFAEVTGLSPGVTYYFKV 977
             V++ W  P     S + GY V+V   +        LP + + T  EVTGL     Y F+V
Sbjct: 13300 VSLSWGKPAYDGGSPIIGYLVEVKRADSDNWVRCNLPQNLQKTRFEVTGLMEDTQYQFRV 13359

Query: 978   FAVSHGRESKP-----------LTAQQTTKLDAPTNLQFVNETDST----VLVRWTPPRA 1022
             +AV+    S P           +      +LDA      +     T    V V+  PP  
Sbjct: 13360 YAVNKIGYSDPSDVPDKHYPKDILIPPEGELDADLRKTLILRAGVTMRLYVPVKGRPP-P 13418

Query: 1023  QITGYRLTVGLTRR-GQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGV 1081
             +IT  +  V L  R G   +     +  +    N   A +Y ++L    G +E      V
Sbjct: 13419 KITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKYILTLENSCGKKEYTIVVKV 13478

Query: 1082  FTTLQPGSSIPPYNTEVTETTIVITWTP------APRIGFKLGVRPSQGGEAPREVTSDS 1135
               T  PG  +     E+++ +  +TW P      +P I + +  R ++        T  S
Sbjct: 13479 LDT--PGPPVNVTVKEISKDSAYVTWEPPIIDGGSPIINYVVQKRDAERKSWSTVTTECS 13536

Query: 1136  G-SIVVSGLTPGVEYVYTIQVLRD------GQERDAPIVNKVVTPLSPPTNLHLEANPDT 1188
               S  V+ L  G  Y + +    +      G+ RDA  V    TP  P  +L + +   +
Sbjct: 13537 KTSFRVANLEEGKSYFFRVFAENEYGIGDPGETRDA--VKASQTP-GPVVDLKVRSVSKS 13593

Query: 1189  GVLTVSWERSTTPD---ITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNV 1245
                ++ W++  +     I GY +        + N  + V+ +     +  +L+ G EY  
Sbjct: 13594 SC-SIGWKKPHSDGGSRIIGYVVDFLT----EENKWQRVMKSLSLQYSAKDLTEGKEYTF 13648

Query: 1246  SVYTVKDDKESVPISDTIIP---AVPPPTDLRFTNIGPDT-------------MRVTWAP 1289
              V    ++ E  P   T++     V P  DL+     PD              + +   P
Sbjct: 13649 RVSAENENGEGTPSEITVVARDDVVAPDLDLKGL---PDLCYLAKENSNFRLKIPIKGKP 13705

Query: 1290  PPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLL-------PGTEYVVSVSSVY 1342
              PS+         S  K E+ +A  +    +++ V T L+          +Y +++ +V 
Sbjct: 13706 APSV---------SWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVA 13756

Query: 1343  EQHEST-PLRGRQKTGLDSPTG-IDFSDITANSFTVHWIAPR----ATITGYRIRHHPEH 1396
                E T  ++   K G+  PTG I F ++TA + T+ W  P+    + IT Y I    + 
Sbjct: 13757 GTKEGTISIKVVGKPGI--PTGPIKFDEVTAEAMTLKWAPPKDDGGSEITNY-ILEKRDS 13813

Query: 1397  FSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN------GREESPLLIGQQSTVSDV 1450
              + +         + +  +T L  G EY   + A N      G +  P++      V D 
Sbjct: 13814 VNNKWVTCASAVQKTTFRVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVPDA 13873

Query: 1451  PRDLEVVAATPTSLLISWDAPAVT----VRYYRITYGETGGNSPVQEFTVPGSKSTATIS 1506
             P    +V     S+ ++W  P  T    +  Y + + E       +    P       ++
Sbjct: 13874 PPPPNIVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTPIRMRDFKVT 13933

Query: 1507  GLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLP-- 1564
             GL  G++Y   V A+   G    S     +     ID P + +V ++  NS+++ W    
Sbjct: 13934 GLTEGLEYEFRVMAINLAGVGKPSLPSEPVVALDPIDPPGKPEVINITRNSVTLIWTEPK 13993

Query: 1565  --SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQ 1622
                   +TGY V           K       +   T+  L    +Y   + A+N +G   
Sbjct: 13994 YDGGHKLTGYIVEKRDLPSKSWMKANHVNVPECAFTVTDLVEGGKYEFRIRAKNTAGAIS 14053

Query: 1623  PLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQV----------------SRYRVTY 1666
                ++  T I + +  A T V   +IK       G                  S  +   
Sbjct: 14054 APSESTETIICKDEYEAPTIVLDPTIKDGLTIKAGDTIVLNAISILGKPLPKSSWSKAGK 14113

Query: 1667  SSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPT 1726
                   I ++   P     T +    +   EYT++             +       P P 
Sbjct: 14114 DIRPSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFGTKVEHVKVTVLDVPGP-PG 14172

Query: 1727  DLKFTQVTPTSLSAQWTPPNVQLTGYRVR--VTPKEKTGPMKEINLAPDSSSV--VVSGL 1782
              ++ + V+    +  WTPP ++  G  ++  +  K +T  +    ++ D  S   V + L
Sbjct: 14173 PVEISNVSAEKATLTWTPP-LEDGGSPIKSYILEKRETSRLLWTVVSEDIQSCRHVATKL 14231

Query: 1783  MVATKYEVSVYALKDTLTSRPAQG----VVTTLENVSPPRRARVTDATETTITISWRTKT 1838
             +   +Y   V A+       P Q     +V       PP +  V++ T+ T T+SW+   
Sbjct: 14232 IQGNEYIFRVSAVNHYGKGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSWKRPV 14291

Query: 1839  E----TITGFQVDAVPANGQTPIQRTIKPDVRSY--TITGLQPGTDYKIYLYTLN----- 1887
             +     ITG+ V+         + R IK  V      +TGLQ G+ Y+  +   N     
Sbjct: 14292 DDGGSEITGYHVERREKKSLRWV-RAIKTPVSDLRCKVTGLQEGSTYEFRVSAENRAGIG 14350

Query: 1888  --DNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPG 1941
                 A  S ++ DA+     PSN     TT  S  ++W  P       ITGY+++++K G
Sbjct: 14351 PPSEASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLAWGKPHYDGGLEITGYVVEHQKVG 14410

Query: 1942  SPPREVVPRPRPG----VTEATITGLEPGTEYTIYVIALKNNQKSEPLI 1986
                 E   +   G    +T+  +  L+   +Y   + A+ +    EP +
Sbjct: 14411 D---EAWIKDTTGTALRITQFVVPDLQTKEKYNFRISAINDAGVGEPAV 14456



 Score =  146 bits (368), Expect = 3e-34
 Identities = 299/1392 (21%), Positives = 517/1392 (37%), Gaps = 202/1392 (14%)

Query: 780   LLPGRKYIVNVYQISEDG-----EQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRP 834
             L+   +YI  V  +++ G     E   I++ +  T P  P  P         I+++W++P
Sbjct: 22899 LIKNNEYIFRVRAVNKYGPGVPVESEPIVARNSFTIPSPPGIPEEVGTGKEHIIIQWTKP 22958

Query: 835   QAP----ITGYRIVYSPSVEGSSTELNLPETANSVTL--SDLQPGVQYNITIYAVEENQE 888
             ++     I+ Y +          T +N         L  + L  G  Y   + AV     
Sbjct: 22959 ESDGGNEISNYLVDKREKKSLRWTRVNKDYVVYDTRLKVTSLMEGCDYQFRVTAVNAAGN 23018

Query: 889   STPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPV 944
             S P       +    S T   P   + V+ T   +++ WT P     + + GY +++   
Sbjct: 23019 SEPSEASNFISCREPSYTPGPPSAPRVVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEK 23078

Query: 945   NLPGEHGQRLPIS-RNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTA----QQTTKLDA 999
             +    +      + RNT   V  L  G  Y F+V AV+    S+   +    +   +++ 
Sbjct: 23079 DTDQWYRVHTNATIRNTEFTVPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEI 23138

Query: 1000  PTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQP-----------RQYNVGPSV 1048
             P +L+  ++   TV +R           RL V ++ R  P               +  + 
Sbjct: 23139 P-DLELADDLKKTVTIRAG------ASLRLMVSVSGRPPPVITWSKQGIDLASRAIIDTT 23191

Query: 1049  SKYPLR-----NLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTI 1103
               Y L      N   A +YT+      G + +     V+ T  P  S+     EV+  ++
Sbjct: 23192 ESYSLLIVDKVNRYDAGKYTIEAENQSGKKSATVLVKVYDTPGPCPSVKV--KEVSRDSV 23249

Query: 1104  VITWT------PAPRIGFKLGVRPSQGGEAPREVTSDSGSIV-VSGLTPGVEYVYTIQ-- 1154
              ITW        AP   + +  R +         T  S ++  +SGL  G  Y + +   
Sbjct: 23250 TITWEIPTIDGGAPVNNYIVEKREAAMRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPE 23309

Query: 1155  ----VLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPD---ITGYR 1207
                 +    +  DA +V++V  PL P     ++    T  +T++WE+        +TGY 
Sbjct: 23310 NIYGIGEPCETSDAVLVSEV--PLVPAKLEVVDVTKST--VTLAWEKPLYDGGSRLTGYV 23365

Query: 1208  ITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEY-----------------NVSVYTV 1250
             +       ++   +   +       T  +L+ G +Y                  V+  TV
Sbjct: 23366 LEACKAGTERWMKVV-TLKPTVLEHTVTSLNEGEQYLFRIRAQNEKGVSEPRETVTAVTV 23424

Query: 1251  KD-------DKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYS 1303
             +D       D  ++P     +PA   P +L         + +   PPP+     F     
Sbjct: 23425 QDLRVLPTIDLSTMPQKTIHVPA-GRPVEL--------VIPIAGRPPPAASW--FFAGSK 23473

Query: 1304  PVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVY-EQHESTPLRGRQKTGLDSPT 1362
               ++E    E     +   +  T +    EY + + +V     E+  +    K G   PT
Sbjct: 23474 LRESERVTVETHTKVAKLTIRETTIRDTGEYTLELKNVTGTTSETIKVIILDKPG--PPT 23531

Query: 1363  G-IDFSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSG-RPREDRVPHSRNSITLT 1416
             G I   +I A S T+ W  P     A ++GY +     H  G  P  + V  +R++   T
Sbjct: 23532 GPIKIDEIDATSITISWEPPELDGGAPLSGYVVEQRDAHRPGWLPVSESV--TRSTFKFT 23589

Query: 1417  NLTPGTEYVVSIVALN----GREESPLLIGQQSTVS--DVPRDLEVVAATPTSLLISWDA 1470
              LT G EYV  + A N    G      +I  +S++     P  L++   +   + ++W  
Sbjct: 23590 RLTEGNEYVFRVAATNRFGIGSYLQSEVIECRSSIRIPGPPETLQIFDVSRDGMTLTWYP 23649

Query: 1471  P----AVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGD 1526
             P       V  Y +   E   +  V+   VP + +    +GL  G++Y   V A+  RG 
Sbjct: 23650 PEDDGGSQVTGYIVERKEVRADRWVRVNKVPVTMTRYRSTGLTEGLEYEHRVTAINARGS 23709

Query: 1527  SPAS--SKPI-SINYRTEIDKPSQMQVTDVQDNSISVKWL----PSSSPVTGYRVTTTPK 1579
                S  SKPI +++      KP   +VTD    S+S+ W        S VTGY +     
Sbjct: 23710 GKPSRPSKPIVAMDPIAPPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKV 23769

Query: 1580  NGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLA 1639
             +    TK  T      E T+  L    EY   V A N  G  +P        +     L 
Sbjct: 23770 DQHEWTKCNTTPTKIREYTLTHLPQGAEYRFRVLACNAGGPGEPAEVPGTVKVTEM--LE 23827

Query: 1640  FTDVDVDS-IKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEY 1698
             + D ++D   +      QG V R  +        I +     +G+ D ++   +     +
Sbjct: 23828 YPDYELDERYQEGIFVRQGGVIRLTIPIKGKPFPICKW--TKEGQ-DISKRAMIATSETH 23884

Query: 1699  TVSVVALHDDMES------------QPLIGTQSTAIPAPTD----LKFTQVTPTSLSAQW 1742
             T  V+   D  +S            +  +  +   I +P      L++  +   S+   W
Sbjct: 23885 TELVIKEADRGDSGTYDLVLENKCGKKAVYIKVRVIGSPNSPEGPLEYDDIQVRSVRVSW 23944

Query: 1743  TPP----NVQLTGYRV--RVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALK 1796
              PP       + GY +  R  PK        I+     +S+VV GL    +Y   V A  
Sbjct: 23945 RPPADDGGADILGYILERREVPK---AAWYTIDSRVRGTSLVVKGLKENVEYHFRVSAEN 24001

Query: 1797  DTLTSRP--AQGVVTTLENVSPPRRA----RVTDATETTITISW-RTKTE---TITGFQV 1846
                 S+P  ++  VT    ++PP        V D T++++++SW R K +    +TG+ +
Sbjct: 24002 QFGISKPLKSEEPVTPKTPLNPPEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRVTGYYI 24061

Query: 1847  DAVPANGQTPIQRTIKPDVRS--YTITGLQPGTDYKIYLYTLND------NARSSPVVI- 1897
             +    +    ++   K  + +  YT+TGL P  +Y+  +   ND      +  S PVV  
Sbjct: 24062 ERKETSTDKWVRHN-KTQITTTMYTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCK 24120

Query: 1898  DASTAIDAPSNLRFLATTPNSLLVSWQPPRA----RITGYIIKYEKPGSPPREVVPRPRP 1953
             D       P  L  L+ + +S+ + W+ P       I GY ++Y + G    +   + R 
Sbjct: 24121 DPFDKPSQPGELEILSISKDSVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERI 24180

Query: 1954  GVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQKTPFVTHPGYDTGNGIQLPG 2013
                + TI GL   TEY   V A      S P                    T   I+   
Sbjct: 24181 KDKQFTIGGLLEATEYEFRVFAENETGLSRP------------------RRTAMSIKTKL 24222

Query: 2014  TSGQQPSVGQQM 2025
             TSG+ P + ++M
Sbjct: 24223 TSGEAPGIRKEM 24234



 Score =  134 bits (338), Expect = 8e-31
 Identities = 286/1432 (19%), Positives = 516/1432 (36%), Gaps = 199/1432 (13%)

Query: 728   VTEITASSFVVSWVSASDTVSGFRVEY--ELSEEGDEP-QYLDLPSTATSVNIPDLLPGR 784
             V+ ++A S V+SW    D        Y  E  E G    Q ++     T + +  L    
Sbjct: 22445 VSSVSAESCVLSWGEPKDGGGTEITNYIVEKRESGTTAWQLVNSSVKRTQIKVTHLTKYM 22504

Query: 785   KYIVNV-----YQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPIT 839
             +Y   V     + +S+  E + I++      P AP  P V  V   ++ +RW  P     
Sbjct: 22505 EYSFRVSSENRFGVSKPLESAPIIAEHPFVPPSAPTRPEVYHVSANAMSIRWEEPYHDGG 22564

Query: 840   GYRIVYSPSVEGSST-----ELNLPETANSVTLSDLQPGVQYNITIYAV------EENQE 888
                I Y    +  +T     E  +P    +  ++ L  G++Y    YA+      + ++ 
Sbjct: 22565 SKIIGYWVEKKERNTILWVKENKVPCLECNYKVTGLVEGLEYQFRTYALNAAGVSKASEA 22624

Query: 889   STPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPV 944
             S P++ Q         + V +P   +  +VT   V+++W+ P     S V GY ++  PV
Sbjct: 22625 SRPIMAQ---------NPVDAPGRPEVTDVTRSTVSLIWSAPAYDGGSKVVGYIIERKPV 22675

Query: 945   NLPGEHGQRLP----ISRNTFAEVTGLSPGVTYYFKVFA------VSHGRESK-PLT--- 990
             +  G+ G+ L     I  + F  VT LS G TY F+V A      +S G ES  P+T   
Sbjct: 22676 SEVGD-GRWLKCNYTIVSDNFFTVTALSEGDTYEFRVLAKNAAGVISKGSESTGPVTCRD 22734

Query: 991   --AQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPR-------- 1040
               A    +LDA  +   V     + LV      A + G      +  +G           
Sbjct: 22735 EYAPPKAELDARLHGDLVTIRAGSDLVL----DAAVGGKPEPKIIWTKGDKELDLCEKVS 22790

Query: 1041  -QYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTL--QPGSSIPPYNTE 1097
              QY    + +     +   + +YT+++     N    KA  V   +   PG       + 
Sbjct: 22791 LQYTGKRATAVIKFCDRSDSGKYTLTVK----NASGTKAVSVMVKVLDSPGPCGKLTVSR 22846

Query: 1098  VTETTIVITWTPAPRIGFKLGVRPSQGGEAP-------REVTSDSGSIVVSGLTPGVEYV 1150
             VT+    + W+            P + G A        R  TS    ++V G  P + YV
Sbjct: 22847 VTQEKCTLAWS-----------LPQEDGGAEITHYIVERRETSRLNWVIVEGECPTLSYV 22895

Query: 1151  YTIQVLRDGQE----------------RDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVS 1194
              T +++++ +                    PIV +    +  P  +  E       + + 
Sbjct: 22896 VT-RLIKNNEYIFRVRAVNKYGPGVPVESEPIVARNSFTIPSPPGIPEEVGTGKEHIIIQ 22954

Query: 1195  WERSTTP---DITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVK 1251
             W +  +    +I+ Y +        +   + +      +     +L  G +Y   V  V 
Sbjct: 22955 WTKPESDGGNEISNYLVDKREKKSLRWTRVNKDYVVYDTRLKVTSLMEGCDYQFRVTAVN 23014

Query: 1252  DDKESVP--ISDTIIPAVP-----PPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSP 1304
                 S P   S+ I    P     PP+  R  +    ++ + W  P   D    +V Y  
Sbjct: 23015 AAGNSEPSEASNFISCREPSYTPGPPSAPRVVDTTKHSISLAWTKP-MYDGGTDIVGYVL 23073

Query: 1305  VKNEEDVAE-----LSISPSDNAVVLTNLLPGTEYVVSVSSV----YEQHESTPLRGRQK 1355
                E+D  +      + +  +    + +L  G +Y   V++V      ++  +       
Sbjct: 23074 EMQEKDTDQWYRVHTNATIRNTEFTVPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPV 23133

Query: 1356  TGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVP-------- 1407
               ++ P  ++ +D    + T+   A    +     R  P     +   D           
Sbjct: 23134 ERIEIPD-LELADDLKKTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAIIDTTE 23192

Query: 1408  -HSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLI 1466
              +S   +   N     +Y +     +G++ + +L+    T    P  ++V   +  S+ I
Sbjct: 23193 SYSLLIVDKVNRYDAGKYTIEAENQSGKKSATVLVKVYDTPGPCP-SVKVKEVSRDSVTI 23251

Query: 1467  SWDAPAVT----VRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYA-- 1520
             +W+ P +     V  Y +   E    +  +  T   SK+   ISGL  G  Y   V    
Sbjct: 23252 TWEIPTIDGGAPVNNYIVEKREAAMRA-FKTVTTKCSKTLYRISGLVEGTMYYFRVLPEN 23310

Query: 1521  VTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKW----LPSSSPVTGYRVTT 1576
             + G G+   +S  + ++    +  P++++V DV  +++++ W        S +TGY +  
Sbjct: 23311 IYGIGEPCETSDAVLVSEVPLV--PAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEA 23368

Query: 1577  TPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPK 1636
                      K  T  P   E T+  L    +Y+  + AQN  G S+P        +   +
Sbjct: 23369 CKAGTERWMKVVTLKPTVLEHTVTSLNEGEQYLFRIRAQNEKGVSEPRETVTAVTVQDLR 23428

Query: 1637  GLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDG--EEDTAELQGLRP 1694
              L   D+     K     P G+     +  +         F A     E +   ++    
Sbjct: 23429 VLPTIDLSTMPQKTI-HVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTK 23487

Query: 1695  GSEYTVSVVALHDD----MESQPLIGTQSTAI---------PAPTDLKFTQVTPTSLSAQ 1741
              ++ T+    + D     +E + + GT S  I         P    +K  ++  TS++  
Sbjct: 23488 VAKLTIRETTIRDTGEYTLELKNVTGTTSETIKVIILDKPGPPTGPIKIDEIDATSITIS 23547

Query: 1742  WTPPNVQ----LTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKD 1797
             W PP +     L+GY V      + G +      P S SV  S        E + Y  + 
Sbjct: 23548 WEPPELDGGAPLSGYVVEQRDAHRPGWL------PVSESVTRSTFKFTRLTEGNEYVFRV 23601

Query: 1798  TLTSRPAQGVVTTLENVS---------PPRRARVTDATETTITISWRTKTET----ITGF 1844
               T+R   G     E +          PP   ++ D +   +T++W    +     +TG+
Sbjct: 23602 AATNRFGIGSYLQSEVIECRSSIRIPGPPETLQIFDVSRDGMTLTWYPPEDDGGSQVTGY 23661

Query: 1845  QVDAVPANGQTPIQRTIKP-DVRSYTITGLQPGTDYKIYLYTLNDNARSSP-------VV 1896
              V+         ++    P  +  Y  TGL  G +Y+  +  +N      P       V 
Sbjct: 23662 IVERKEVRADRWVRVNKVPVTMTRYRSTGLTEGLEYEHRVTAINARGSGKPSRPSKPIVA 23721

Query: 1897  IDASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREVVPRPR 1952
             +D       P N R   TT  S+ ++W  P     +++TGY+I+ +K             
Sbjct: 23722 MDPIAPPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTKCNTTP 23781

Query: 1953  PGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQKTPFVTHPGYD 2004
               + E T+T L  G EY   V+A       EP      TV+ T  + +P Y+
Sbjct: 23782 TKIREYTLTHLPQGAEYRFRVLACNAGGPGEP-AEVPGTVKVTEMLEYPDYE 23832



 Score =  132 bits (333), Expect = 3e-30
 Identities = 291/1351 (21%), Positives = 478/1351 (35%), Gaps = 186/1351 (13%)

Query: 771   TATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVR 830
             T  S++  D     KYI+ +   S  G +S  ++      P  P +  V +V   S  + 
Sbjct: 17773 TQLSIDNCDRNDAGKYILKLENSS--GSKSAFVTVKVLDTPGPPQNLAVKEVRKDSAFLV 17830

Query: 831   WSRP----QAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEEN 886
             W  P     A +  Y I    S   +   ++   +  S  + +L  G  Y   + A  E 
Sbjct: 17831 WEPPIIDGGAKVKNYVIDKRESTRKAYANVSSKCSKTSFKVENLTEGAIYYFRVMAENEF 17890

Query: 887   QESTPVVIQQETTGTPRSDTVPSPRD-LQFVEVTDVKVTIMWTPPE----SAVTGYRVDV 941
                 PV    ET    ++   PSP   +   +V+    ++MW  PE    S V GY V++
Sbjct: 17891 GVGVPV----ETVDAVKAAEPPSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVEM 17946

Query: 942   IPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKP-----------LT 990
              P     E    +  S+   A VTGLS G  Y F+V A +   +S P           LT
Sbjct: 17947 QPKGT--EKWSIVAESKVCNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLT 18004

Query: 991   AQQTTKLDAPT-NLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQP----RQYNVG 1045
              Q + KL   T ++Q   +    + V   P        R  +   + G+P     + NV 
Sbjct: 18005 IQPSLKLPFNTYSIQAGEDLKIEIPVIGRP--------RPNISWVKDGEPLKQTTRVNVE 18056

Query: 1046  PSVSKYPLR----NLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYN-TEVTE 1100
              + +   L     N     +YTV+     G   + +   V    +PG  + P    EV+ 
Sbjct: 18057 ETATSTVLHIKEGNKDDFGKYTVTATNSAGT--ATENLSVIVLEKPGPPVGPVRFDEVSA 18114

Query: 1101  TTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIV----------VSGLTPGVEYV 1150
               +VI+W P    G   G + S      R+ T+ +  +V          ++ L  G EY 
Sbjct: 18115 DFVVISWEPPAYTG---GCQISNYIVEKRDTTTTTWHMVSATVARTTIKITKLKTGTEYQ 18171

Query: 1151  YTIQVLRDGQERDAPIVNKVVTPLSP-----PTNLHLEANPDTGVLTVSWERSTTPD--- 1202
             + I    +   + AP+ +K V    P     P       +     + V W          
Sbjct: 18172 FRI-FAENRYGKSAPLDSKAVIVQYPFKEPGPPGTPFVTSISKDQMLVQWHEPVNDGGTK 18230

Query: 1203  ITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYN--VSVYTVKDDKESVPIS 1260
             I GY +     N      L +    D    T   L  GLEY   VS   +    +   +S
Sbjct: 18231 IIGYHLEQKEKNSILWVKLNKTPIQDTKFKT-TGLDEGLEYEFKVSAENIVGIGKPSKVS 18289

Query: 1261  DTIIPAVP--PPTDLRFTNIGPDTMRVTWAPPP---SIDLTNFLVRYSPVKNEEDVAELS 1315
             +  +   P  PP       I  + + + W  P       +T ++V     K+  D   + 
Sbjct: 18290 ECFVARDPCDPPGRPEAIVITRNNVTLKWKKPAYDGGSKITGYIVEK---KDLPDGRWMK 18346

Query: 1316  ISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFT 1375
              S        TN+L  TE+ VS   V +Q     +  R   G  S        ITA    
Sbjct: 18347 AS-------FTNVLE-TEFTVS-GLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARD-- 18395

Query: 1376  VHWIAPRATITG-YR---IRHHPEHF------SGRPREDRV--------------PHSRN 1411
                 AP A++   Y+   + H  E F       G+P  D V                 ++
Sbjct: 18396 -EIDAPNASLDPKYKDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKS 18454

Query: 1412  SITLTNL-------TPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSL 1464
             +I  T L       T G +Y++ +  + G +  P+ +            L+V   T    
Sbjct: 18455 TIQKTTLVVKDCIRTDGGQYILKLSNVGGTKSIPITVKVLDRPGPPEGPLKVTGVTAEKC 18514

Query: 1465  LISWDAP----AVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYA 1520
              ++W+ P       + +Y I   ET   S  Q  T   + +   ++ L PG +Y   V A
Sbjct: 18515 YLAWNPPLQDGGANISHYIIEKRETSRLSWTQVSTEVQALNYK-VTKLLPGNEYIFRVMA 18573

Query: 1521  VTGRG-DSPASSKPISI-NYRTEIDKPSQMQVTDVQDNSISVKWL----PSSSPVTGYRV 1574
             V   G   P  S P++  N       PS  +V+ +  +S+ V W        + + GY +
Sbjct: 18574 VNKYGIGEPLESGPVTACNPYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYIL 18633

Query: 1575  TTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQT------- 1627
                 K G   TK          + + GL     Y   V A+N +G  +P   +       
Sbjct: 18634 EKRDKEGVRWTKCNKKTLTDLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRACD 18693

Query: 1628  AVTNIDRPKGLAFTDVDVDSIKIAWESP----QGQVSRYRVTYSSPEDGIHELFPAPDGE 1683
             A+     P     TD    S+ +AW  P       V  Y V               P G 
Sbjct: 18694 ALYPPGPPSNPKVTDTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAADEWTTCTPPTGL 18753

Query: 1684  EDTA-ELQGLRPGSEYTVSVVALHDDMESQPL-----IGTQSTAIPAPTDLKFTQVTPTS 1737
             +     +  L+  +EY   + A++ +   +P      +  Q    P   +L         
Sbjct: 18754 QGKQFTVTKLKENTEYNFRICAINSEGVGEPATLPGSVVAQERIEPPEIELDADLRKVVV 18813

Query: 1738  LSAQWTPPNVQLTGYRVRVTPKEKTGPM----KEINLAPDSSSVVVSGLMV------ATK 1787
             L A  T         R+ VT K +  P     K   +  D + + V+           T+
Sbjct: 18814 LRASAT--------LRLFVTIKGRPEPEVKWEKAEGILTDRAQIEVTSSFTMLVIDNVTR 18865

Query: 1788  YEVSVY--ALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKT----ETI 1841
             ++   Y   L++   S+ A   V  L++ S P    + +  + ++T+SW          I
Sbjct: 18866 FDSGRYNLTLENNSGSKTAFVNVRVLDSPSAPVNLTIREVKKDSVTLSWEPPLIDGGAKI 18925

Query: 1842  TGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDAST 1901
             T + V+      +     T      ++ I  LQ G  Y   +   N+     P       
Sbjct: 18926 TNYIVEKRETTRKAYATITNNCTKTTFRIENLQEGCSYYFRVLASNEYGIGLPAETTEPV 18985

Query: 1902  AIDAP----SNLRFLATTPNSLLVSWQPPRA----RITGYIIKYEKPGSPPREVVPRPRP 1953
              +  P      +  +  T N+  + W+ P +    +ITGY+++ +  GS       + + 
Sbjct: 18986 KVSEPPLPPGRVTLVDVTRNTATIKWEKPESDGGSKITGYVVEMQTKGSEKWSTCTQVK- 19044

Query: 1954  GVTEATITGLEPGTEYTIYVIALKNNQKSEP 1984
                EATI+GL  G EY   V A+    +S+P
Sbjct: 19045 -TLEATISGLTAGEEYVFRVAAVNEKGRSDP 19074



 Score =  132 bits (332), Expect = 4e-30
 Identities = 282/1282 (21%), Positives = 484/1282 (37%), Gaps = 198/1282 (15%)

Query: 611   PVEVFITETPSQPNSHPIQWNAP---QPSHISKYILRWRPKNSVGRWKEATIPGHLNSYT 667
             PV V + E     +S  + W  P     S I  Y+++ R       W   T      S+ 
Sbjct: 13485 PVNVTVKEISK--DSAYVTWEPPIIDGGSPIINYVVQKRDAERKS-WSTVTTECSKTSFR 13541

Query: 668   IKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSES 727
             +  L+ G  Y  ++ +  +YG  +               T + V    TP  P+V     
Sbjct: 13542 VANLEEGKSYFFRVFAENEYGIGDPGE------------TRDAVKASQTP-GPVVDLK-- 13586

Query: 728   VTEITASSFVVSWVS----ASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPG 783
             V  ++ SS  + W          + G+ V++ L+EE    + +   S +   +  DL  G
Sbjct: 13587 VRSVSKSSCSIGWKKPHSDGGSRIIGYVVDF-LTEENKWQRVMK--SLSLQYSAKDLTEG 13643

Query: 784   RKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWS---RPQAPITG 840
             ++Y   V   +E+GE +    T         PD  +  + D   + + +   R + PI G
Sbjct: 13644 KEYTFRVSAENENGEGTPSEITVVARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPIKG 13703

Query: 841   YRIVYSPSVE--------GSSTELNLPETANSVTLS--DLQPGV--QYNITIYAVEENQE 888
                  +PSV          + T +++  +A + TL   D Q     +Y IT+  V   +E
Sbjct: 13704 KP---APSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKE 13760

Query: 889   STPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPV 944
              T   I  +  G P   T P    ++F EVT   +T+ W PP+    S +T Y ++    
Sbjct: 13761 GT---ISIKVVGKPGIPTGP----IKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDS 13813

Query: 945   NLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKV-----FAVSHGRESKPLTAQQTTKL-D 998
                        + + TF  VT L  G+ Y F+V     + V  G +S+P+ A+    + D
Sbjct: 13814 VNNKWVTCASAVQKTTF-RVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVPD 13872

Query: 999   APTNLQFVNETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGP-SVSKYPL 1053
             AP     V+    +V + WT P+    + ITGY L          ++ N  P  +  + +
Sbjct: 13873 APPPPNIVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTPIRMRDFKV 13932

Query: 1054  RNLQPASEYTVSLVAIK----GNQESPKATGVFTTLQPGSSIPPYNTEV---TETTIVIT 1106
               L    EY   ++AI     G    P    V   L P    PP   EV   T  ++ + 
Sbjct: 13933 TGLTEGLEYEFRVMAINLAGVGKPSLPSEPVV--ALDPID--PPGKPEVINITRNSVTLI 13988

Query: 1107  WT-PAPRIGFKLGVR-------PSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRD 1158
             WT P    G KL          PS+       V     +  V+ L  G +Y + I+    
Sbjct: 13989 WTEPKYDGGHKLTGYIVEKRDLPSKSWMKANHVNVPECAFTVTDLVEGGKYEFRIRAKNT 14048

Query: 1159  GQERDAPIVN----------KVVTPLSPPT---NLHLEANPDTGVLTV-----------S 1194
                  AP  +          +  T +  PT    L ++A  DT VL             S
Sbjct: 14049 AGAISAPSESTETIICKDEYEAPTIVLDPTIKDGLTIKAG-DTIVLNAISILGKPLPKSS 14107

Query: 1195  WERS----TTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTV 1250
             W ++       DIT  +IT+TPT+     +++     D    T    +P   +   V  V
Sbjct: 14108 WSKAGKDIRPSDIT--QITSTPTSSML--TIKYATRKDAGEYTITATNP---FGTKVEHV 14160

Query: 1251  KDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEED 1310
             K          T++    PP  +  +N+  +   +TW PP   D  + +  Y   K E  
Sbjct: 14161 KV---------TVLDVPGPPGPVEISNVSAEKATLTWTPPLE-DGGSPIKSYILEKRETS 14210

Query: 1311  VAELSISPSDNAV---VLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLD------SP 1361
                 ++   D      V T L+ G EY+  VS+V    +  P++      +D       P
Sbjct: 14211 RLLWTVVSEDIQSCRHVATKLIQGNEYIFRVSAVNHYGKGEPVQSEPVKMVDRFGPPGPP 14270

Query: 1362  TGIDFSDITANSFTVHWIAP----RATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTN 1417
                + S++T N+ TV W  P     + ITGY +    +      R  + P S     +T 
Sbjct: 14271 EKPEVSNVTKNTATVSWKRPVDDGGSEITGYHVERREKKSLRWVRAIKTPVSDLRCKVTG 14330

Query: 1418  LTPGTEYVVSIVALNGREESP-------LLIGQQSTVSDVPRDLEVVAATPTSLLISWDA 1470
             L  G+ Y   + A N     P       +L+   +     P +  V   T  S  ++W  
Sbjct: 14331 LQEGSTYEFRVSAENRAGIGPPSEASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLAWGK 14390

Query: 1471  P----AVTVRYYRITYGETGGNSPVQEFTVPGSKSTA-TISGLKPGVDYTITVYAVTGRG 1525
             P     + +  Y + + + G  + +++ T    + T   +  L+    Y   + A+   G
Sbjct: 14391 PHYDGGLEITGYVVEHQKVGDEAWIKDTTGTALRITQFVVPDLQTKEKYNFRISAINDAG 14450

Query: 1526  -DSPASSKPISINYR---TEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNG 1581
                PA    + I  R    + +  ++++ T V    +S++            VT T  N 
Sbjct: 14451 VGEPAVIPDVEIVEREMAPDFELDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNI 14510

Query: 1582  PGPTKTKTAGPDQTEMTIE---GLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRP-KG 1637
                 +      +   + I        T ++V+++  +NP+G+    V   V +   P   
Sbjct: 14511 NLKNRANIENTESFTLLIIPECNRYDTGKFVMTI--ENPAGKKSGFVNVRVLDTPGPVLN 14568

Query: 1638  LAFTDVDVDSIKIAWESP----QGQVSRY--------RVTYSSPEDGIHELFPAPDGEED 1685
             L  TD+  DS+ + W+ P      +++ Y        R +YS+     H+          
Sbjct: 14569 LRPTDITKDSVTLHWDLPLIDGGSRITNYIVEKREATRKSYSTATTKCHKC--------- 14619

Query: 1686  TAELQGLRPGSEYTVSVVALHDDMESQPLIGTQ---STAIPAPTD-LKFTQVTPTSLSAQ 1741
             T ++ GL  G EY   V+A ++    +P   T+   ++  P+P D L    +T +++S  
Sbjct: 14620 TYKVTGLSEGCEYFFRVMAENEYGIGEPTETTEPVKASEAPSPPDSLNIMDITKSTVSLA 14679

Query: 1742  WTPP----NVQLTGYRVRVTPK 1759
             W  P      ++TGY +    K
Sbjct: 14680 WPKPKHDGGSKITGYVIEAQRK 14701



 Score =  129 bits (324), Expect = 3e-29
 Identities = 296/1415 (20%), Positives = 523/1415 (36%), Gaps = 202/1415 (14%)

Query: 728   VTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTAT----SVNIPDLLPG 783
             + ++++    V W    D   G  ++  + E+ +  + +    +AT       +  L+ G
Sbjct: 12000 IVDVSSDRCTVCWDPPEDD-GGCEIQNYILEKCETKRMVWSTYSATVLTPGTTVTRLIEG 12058

Query: 784   RKYIVNVYQISEDG-----EQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ--- 835
              +YI  V   ++ G     E   +++ ++   P  P  P V +V    + V W+ P+   
Sbjct: 12059 NEYIFRVRAENKIGTGPPTESKPVIAKTKYDKPGRPDPPEVTKVSKEEMTVVWNPPEYDG 12118

Query: 836   -APITGYRIVYSPSVEGSSTELN---LPETANSVTLSDLQPGVQYNITIYAVEENQESTP 891
                ITGY +            +N   +PE    V   +L P  +Y   + A  E     P
Sbjct: 12119 GKSITGYFLEKKEKHSTRWVPVNKSAIPERRMKV--QNLLPDHEYQFRVKAENEIGIGEP 12176

Query: 892   VVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPVNL- 946
              +  +        +    P + + V+ T   +T+ W  P     + + GY V++ P    
Sbjct: 12177 SLPSRPVVAKDPIEPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAPIIGYVVEMRPKIAD 12236

Query: 947   --PGEHGQRL----PISRNTFAEVTGLSPGVTYYFKVFA---VSHGRESKPLTAQQTTKL 997
               P E  +R      + R  F  VT L     Y F+V A   V  GR ++   A +  ++
Sbjct: 12237 ASPDEGWKRCNAAAQLVRKEFT-VTSLDENQEYEFRVCAQNQVGIGRPAELKEAIKPKEI 12295

Query: 998   DAPTNLQFVNETDSTVLVRWT-----------PPRAQITGYRLTV-GLTRRGQPRQYNVG 1045
               P  +         V+VR              P  ++T  ++ +  + R+GQ    +  
Sbjct: 12296 LEPPEIDLDASMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVVRKGQVDLVDT- 12354

Query: 1046  PSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVI 1105
              +    P      + +Y+++LV   G +       V  T  P S +    ++VT+T+  +
Sbjct: 12355 MAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFVNVRVLDTPGPVSDLKV--SDVTKTSCHV 12412

Query: 1106  TWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIV----------VSGLTPGVEYVYTIQV 1155
             +W P    G   G + +      RE    + S V          V+ L PG EY + +  
Sbjct: 12413 SWAPPENDG---GSQVTHYIVEKREADRKTWSTVTPEVKKTSFHVTNLVPGNEYYFRVTA 12469

Query: 1156  LRD---GQERDAPIVNKVVTPLS---PPTNLHLEANPDTGVLTVSWE---RSTTPDITGY 1206
             + +   G   D P       PLS   PP  L +         T++W    R     I GY
Sbjct: 12470 VNEYGPGVPTDVPKPVLASDPLSEPDPPRKLEVTEMTKNSA-TLAWLPPLRDGGAKIDGY 12528

Query: 1207  RITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYT-----VKDDKESVPISD 1261
              IT+     Q  +   E       S     L  G +Y   V       V   +E+  + +
Sbjct: 12529 -ITSYREEEQPADRWTEYSVVKDLSLVVTGLKEGKKYKFRVAARNAVGVSLPREAEGVYE 12587

Query: 1262  TIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVK---NEEDV---AELS 1315
                  +PP        + P+ + +       I+   +   +   K    E++V   + L+
Sbjct: 12588 AKEQLLPPKI------LMPEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLA 12641

Query: 1316  ISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSP----TGIDFSDITA 1371
             +  +D++ +L       +     S   E    T  +  +   +D+P       D SDI A
Sbjct: 12642 VHKADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPGPPQPPFDISDIDA 12701

Query: 1372  NSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPH----SRNSITLTNLTPGTEYVVS 1427
             ++ ++ W  P     G  I ++        R D V      ++ S  +  L PG EY+  
Sbjct: 12702 DACSLSWHIPLED-GGSNITNYIVEKCDVSRGDWVTALASVTKTSCRVGKLIPGQEYIFR 12760

Query: 1428  IVALN--GREE---SPLLIGQ-QSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRIT 1481
             + A N  G  E   SP ++ Q    V   P++  V       + ++WD P          
Sbjct: 12761 VRAENRFGISEPLTSPKMVAQFPFGVPSEPKNARVTKVNKDCIFVAWDRP---------- 12810

Query: 1482  YGETGGNSPVQEFTVPGSKSTATI----------------SGLKPGVDYTITVYAVTGRG 1525
               ++ G SP+  + +   +  + +                +GL  G++Y+  +YA+   G
Sbjct: 12811 --DSDGGSPIIGYLIERKERNSLLWVKANDTLVRSTEYPCAGLVEGLEYSFRIYALNKAG 12868

Query: 1526  DSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWL----PSSSPVTGYRVTTTPKNG 1581
              SP S     +  R  +D P + +V DV  +++S+ W        S + GY V      G
Sbjct: 12869 SSPPSKPTEYVTARMPVDPPGKPEVIDVTKSTVSLIWARPKHDGGSKIIGYFVEACKLPG 12928

Query: 1582  PGPTKTKTAGPD--QTEMTIEGLQPTVEYVVSVYAQN------PSGESQP---LVQTAVT 1630
                 +  TA     Q E T  GL+   +Y     A+       PS  S P   L +    
Sbjct: 12929 DKWVRCNTAPHQIPQEEYTATGLEEKAQYQFRAIARTAVNISPPSEPSDPVTILAENVPP 12988

Query: 1631  NIDRPKGL-------AFTDVDVDSIKIAWESPQGQVS-RYRVTYSSPEDGIHELFPAPDG 1682
              ID    +       A T+V +D+    +  P   VS +   T   P +GI     A   
Sbjct: 12989 RIDLSVAMKSLLTVKAGTNVCLDA--TVFGKPMPTVSWKKDGTLLKPAEGIK---MAMQR 13043

Query: 1683  EEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPA-PTDLKFTQVTPTSLSAQ 1741
                T EL  +        ++ A +        I  +    P  P  +K  ++        
Sbjct: 13044 NLCTLELFSVNRKDSGDYTITAENSSGSKSATIKLKVLDKPGPPASVKINKMYSDRAMLS 13103

Query: 1742  WTPP----NVQLTGYRVRVTPKEKTGP-MKEINLAPDSSSVVVSGLMVATKYEVSV---- 1792
             W PP      ++T Y   V  +E + P   +++     +S  V  L+   +Y+  +    
Sbjct: 13104 WEPPLEDGGSEITNY--IVDKRETSRPNWAQVSATVPITSCSVEKLIEGHEYQFRICAEN 13161

Query: 1793  -YALKDTLTSRPAQGVVTTLENVSPPRRAR---VTDATETTITISWRTKTE----TITGF 1844
              Y + D + + PA           PP R     +++ T+  +T+SW+   +     ITG+
Sbjct: 13162 KYGVGDPVFTEPA----IAKNPYDPPGRCDPPVISNITKDHMTVSWKPPADDGGSPITGY 13217

Query: 1845  QVDAVPANGQTPIQRTIKPDV-RSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAI 1903
              ++          +   KP + R+   TGLQ GT+Y+  +  +N      P   DAS A 
Sbjct: 13218 LLEKRETQAVNWTKVNRKPIIERTLKATGLQEGTEYEFRVTAINKAGPGKP--SDASKAA 13275

Query: 1904  DA---------PSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREVVPR 1950
              A         P+  +   TT +S+ +SW  P     + I GY+++ ++  S        
Sbjct: 13276 YARDPQYPPGPPAFPKVYDTTRSSVSLSWGKPAYDGGSPIIGYLVEVKRADSDNWVRCNL 13335

Query: 1951  PRP-GVTEATITGLEPGTEYTIYVIALKNNQKSEP 1984
             P+    T   +TGL   T+Y   V A+     S+P
Sbjct: 13336 PQNLQKTRFEVTGLMEDTQYQFRVYAVNKIGYSDP 13370



 Score =  123 bits (309), Expect = 2e-27
 Identities = 282/1358 (20%), Positives = 482/1358 (35%), Gaps = 200/1358 (14%)

Query: 780   LLPGRKYIVNVYQISEDGE----QSLILSTSQTTAPDAPPD-PTVDQVDDTSIVVRWSRP 834
             L+ G +YI  V  ++  G+    QS  +       P  PP+ P V  V   +  V W RP
Sbjct: 14231 LIQGNEYIFRVSAVNHYGKGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSWKRP 14290

Query: 835   Q----APITGYRIVYSPSVEGSSTE-LNLPETANSVTLSDLQPGVQYNITIYA-----VE 884
                  + ITGY +             +  P +     ++ LQ G  Y   + A     + 
Sbjct: 14291 VDDGGSEITGYHVERREKKSLRWVRAIKTPVSDLRCKVTGLQEGSTYEFRVSAENRAGIG 14350

Query: 885   ENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPES----AVTGYRVD 940
                E++  V+ ++    P   + P   D      T    ++ W  P       +TGY V+
Sbjct: 14351 PPSEASDSVLMKDAAYPPGPPSNPHVTD-----TTKKSASLAWGKPHYDGGLEITGYVVE 14405

Query: 941   VIPVN----LPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQ--QT 994
                V     +    G  L I++     V  L     Y F++ A++     +P      + 
Sbjct: 14406 HQKVGDEAWIKDTTGTALRITQFV---VPDLQTKEKYNFRISAINDAGVGEPAVIPDVEI 14462

Query: 995   TKLDAPTNLQFVNETDSTVLVR-------WTP----PRAQITGYRLTVGLTRRGQPRQYN 1043
              + +   + +   E   T++VR       + P    P  ++T  +  + L  R       
Sbjct: 14463 VEREMAPDFELDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKNRANIENTE 14522

Query: 1044  VGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTI 1103
                ++   P  N     ++ +++    G +       V  T  P  ++ P  T++T+ ++
Sbjct: 14523 -SFTLLIIPECNRYDTGKFVMTIENPAGKKSGFVNVRVLDTPGPVLNLRP--TDITKDSV 14579

Query: 1104  VITWT-PAPRIGFKLGVRPSQGGEAPREVTSDSGS------IVVSGLTPGVEYVYTIQVL 1156
              + W  P    G ++     +  EA R+  S + +        V+GL+ G EY + +   
Sbjct: 14580 TLHWDLPLIDGGSRITNYIVEKREATRKSYSTATTKCHKCTYKVTGLSEGCEYFFRVMAE 14639

Query: 1157  RD---GQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPD---ITGYRITT 1210
              +   G+  +     K     SPP +L++  +     ++++W +        ITGY I  
Sbjct: 14640 NEYGIGEPTETTEPVKASEAPSPPDSLNI-MDITKSTVSLAWPKPKHDGGSKITGYVIEA 14698

Query: 1211  TPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTII----PA 1266
                   Q   +  V   +   C   NL+ G EY   V  V     S P     +      
Sbjct: 14699 QRKGSDQWTHITTVKGLE---CVVRNLTEGEEYTFQVMAVNSAGRSAPRESRPVIVKEQT 14755

Query: 1267  VPPPTDLR-------FTNIGPDT---MRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSI 1316
             + P  DLR           G +    + V   P P++            K  + + + + 
Sbjct: 14756 MLPELDLRGIYQKLVIAKAGDNIKVEIPVLGRPKPTVTW----------KKGDQILKQTQ 14805

Query: 1317  SPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGL-------------DSPTG 1363
               +      + +L   E V S S  Y      PL  R   G                PTG
Sbjct: 14806 RVNFETTATSTILNINECVRSDSGPY------PLTARNIVGEVGDVITIQVHDIPGPPTG 14859

Query: 1364  -IDFSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNL 1418
              I F +++++  T  W  P       I+ Y +       S    E      R +   T L
Sbjct: 14860 PIKFDEVSSDFVTFSWDPPENDGGVPISNYVVEMRQTD-STTWVELATTVIRTTYKATRL 14918

Query: 1419  TPGTEYVVSIVALN------GREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAP- 1471
             T G EY   + A N      G   + ++      V   P   +V A T  S+ ISW  P 
Sbjct: 14919 TTGLEYQFRVKAQNRYGVGPGITSACIVANYPFKVPGPPGTPQVTAVTKDSMTISWHEPL 14978

Query: 1472  ---AVTVRYYRITYGETGGN--SPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGD 1526
                   +  Y +   E  G     V +  VPG+   +  SGL  G+ Y   V A    G 
Sbjct: 14979 SDGGSPILGYHVERKERNGILWQTVSKALVPGNIFKS--SGLTDGIAYEFRVIAENMAGK 15036

Query: 1527  SPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKW----LPSSSPVTGYRVTTTPKNGP 1582
             S  S     +     ID P +    ++  +++++KW          +T Y V        
Sbjct: 15037 SKPSKPSEPMLALDPIDPPGKPVPLNITRHTVTLKWAKPEYTGGFKITSYIVEKRDLPNG 15096

Query: 1583  GPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQ--TAVTNIDRPKGLAF 1640
                K   +   + E T+ GL     Y   V A+N +G   P  +   A+T  D       
Sbjct: 15097 RWLKANFSNILENEFTVSGLTEDAAYEFRVIAKNAAGAISPPSEPSDAITCRD------- 15149

Query: 1641  TDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGL-------- 1692
              DV+   IK+  +     + +    +    D      P  +  +D  EL+G         
Sbjct: 15150 -DVEAPKIKVDVKFKDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIA 15208

Query: 1693  -------------RPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTD--LKFTQVTPTS 1737
                          R    YT++  A +    ++ +   +    P P +  L  T+VT   
Sbjct: 15209 DFSTNLVNKDSTRRDSGAYTLT--ATNPGGFAKHIFNVKVLDRPGPPEGPLAVTEVTSEK 15266

Query: 1738  LSAQWTPP----NVQLTGYRVRVTPKEKTGPMKEINLAPD--SSSVVVSGLMVATKY--- 1788
                 W PP      ++  Y   +  K +T  +   N+A +   + + V+ L+   +Y   
Sbjct: 15267 CVLSWFPPLDDGGAKIDHY---IVQKRETSRLAWTNVASEVQVTKLKVTKLLKGNEYIFR 15323

Query: 1789  --EVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISW----RTKTETIT 1842
                V+ Y + + L S P    V       PP+   VT  T+ ++ + W          I 
Sbjct: 15324 VMAVNKYGVGEPLESEPVL-AVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEII 15382

Query: 1843  GFQVDAVPANGQTPIQRTIK--PDVRSYTITGLQPGTDYKIYLYTLNDNARSSP------ 1894
              + V+     GQ  I+   K   D+R Y ++GL  G +Y+  +   N    S+P      
Sbjct: 15383 NYIVERRDKAGQRWIKCNKKTLTDLR-YKVSGLTEGHEYEFRIMAENAAGISAPSPTSPF 15441

Query: 1895  -VVIDASTAIDAPSNLRFLATTPNSLLVSWQPP----RARITGYIIKYEKPGSPPREVVP 1949
                 D       P N R L T+ +S+ ++W  P     + ITGY+++   P     ++V 
Sbjct: 15442 YKACDTVFKPGPPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQIVT 15501

Query: 1950  RPRP-GVTEATITGLEPGTEYTIYVIALKNNQKSEPLI 1986
              P     T  TITGL    EY I + A+ +    EP +
Sbjct: 15502 PPAGLKATSYTITGLTENQEYKIRIYAMNSEGLGEPAL 15539



 Score =  121 bits (303), Expect = 9e-27
 Identities = 287/1414 (20%), Positives = 508/1414 (35%), Gaps = 177/1414 (12%)

Query: 610   GPVEVFITETPSQPNSHPIQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSY 666
             GP E  +  T        + WN P     ++IS YI+  R  + +  W + +      +Y
Sbjct: 18498 GPPEGPLKVTGVTAEKCYLAWNPPLQDGGANISHYIIEKRETSRLS-WTQVSTEVQALNY 18556

Query: 667   TIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSE 726
              +  L PG  Y  +++++ +YG  E             P+ S  VT       P   ++ 
Sbjct: 18557 KVTKLLPGNEYIFRVMAVNKYGIGE-------------PLESGPVTACNPYKPPGPPSTP 18603

Query: 727   SVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEP-----QYLDLPSTATSVNIPDLL 781
              V+ IT  S VV+W    D   G  +E  + E+ D+      +      T   + +  L 
Sbjct: 18604 EVSAITKDSMVVTWARPVDD-GGTEIEGYILEKRDKEGVRWTKCNKKTLTDLRLRVTGLT 18662

Query: 782   PGRKY-----IVNVYQISEDGEQSLILSTSQTTAPDAPP-DPTVDQVDDTSIVVRWSRP- 834
              G  Y       N   + E  E S+         P  PP +P V     +S+ + WS+P 
Sbjct: 18663 EGHSYEFRVAAENAAGVGEPSEPSVFYRACDALYPPGPPSNPKVTDTSRSSVSLAWSKPI 18722

Query: 835   ---QAPITGYRIVYSPSVEGSSTELNLPE--TANSVTLSDLQPGVQYNITIYAVEENQES 889
                 AP+ GY +    +     T    P        T++ L+   +YN  I A+      
Sbjct: 18723 YDGGAPVKGYVVEVKEAAADEWTTCTPPTGLQGKQFTVTKLKENTEYNFRICAINSEGVG 18782

Query: 890   TPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVK--------VTIMWTP-PE---SAVTGY 937
              P  +        R +      D    +V  ++        VTI   P PE       G 
Sbjct: 18783 EPATLPGSVVAQERIEPPEIELDADLRKVVVLRASATLRLFVTIKGRPEPEVKWEKAEGI 18842

Query: 938   RVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKL 997
               D   + +          +      VT    G   Y      + G ++  +  +     
Sbjct: 18843 LTDRAQIEVTSS------FTMLVIDNVTRFDSG--RYNLTLENNSGSKTAFVNVRVLDSP 18894

Query: 998   DAPTNLQFVNETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSVSKYPL 1053
              AP NL        +V + W PP     A+IT Y +    T R          + + + +
Sbjct: 18895 SAPVNLTIREVKKDSVTLSWEPPLIDGGAKITNYIVEKRETTRKAYATITNNCTKTTFRI 18954

Query: 1054  RNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYN------TEVTETTIVITW 1107
              NLQ    Y   ++A   + E        TT     S PP         +VT  T  I W
Sbjct: 18955 ENLQEGCSYYFRVLA---SNEYGIGLPAETTEPVKVSEPPLPPGRVTLVDVTRNTATIKW 19011

Query: 1108  T-PAPRIGFKLG----VRPSQGGEAPREVTS-DSGSIVVSGLTPGVEYVYTIQVLR---- 1157
               P    G K+        ++G E     T   +    +SGLT G EYV+ +  +     
Sbjct: 19012 EKPESDGGSKITGYVVEMQTKGSEKWSTCTQVKTLEATISGLTAGEEYVFRVAAVNEKGR 19071

Query: 1158  -DGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGY-RITTTPTNG 1215
              D ++   P++ + +  + P   L            V        D+    R   T    
Sbjct: 19072 SDPRQLGVPVIARDIE-IKPSVELPFHT------FNVKAREQLKIDVPFKGRPQATVNWR 19124

Query: 1216  QQGNSLEEVVHADQSSC---TFDNLSPGLEYNVSVYTVKDDKES----VPISDTIIPAVP 1268
             + G +L+E    + SS    T  ++    + +V  Y +     +    VPI+  ++    
Sbjct: 19125 KDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSNSAGSITVPITIIVLDRPG 19184

Query: 1269  PPTDLRFTNIGPDTMRVTWAPPP---SIDLTNFLVRYSPVKNEEDVAE---LSISPSDNA 1322
             PP  +R   +  D++ ++W PP       ++N++V     K E        +S + +  +
Sbjct: 19185 PPGPIRIDEVSCDSITISWNPPEYDGGCQISNYIVE----KKETTSTTWHIVSQAVARTS 19240

Query: 1323  VVLTNLLPGTEYVVSVSS-----VYEQHESTPLRGRQKTGLDSPTGI-DFSDITANSFTV 1376
             + +  L  G+EY   V +          ES+ +          P G       T ++  V
Sbjct: 19241 IKIVRLTTGSEYQFRVCAENRYGKSSYSESSAVVAEYPFSPPGPPGTPKVVHATKSTMLV 19300

Query: 1377  HWIAP----RATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN 1432
              W  P     + + GY + +         + +++  +   + ++ L  G  Y   + A N
Sbjct: 19301 TWQVPVNDGGSRVIGYHLEYKERSSILWSKANKILIADTQMKVSGLDEGLMYEYRVYAEN 19360

Query: 1433  ----GREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAP----AVTVRYYRITYGE 1484
                 G+              D P   EV   T  S+ + W  P       +  Y +   E
Sbjct: 19361 IAGIGKCSKSCEPVPARDPCDPPGQPEVTNITRKSVSLKWSKPHYDGGAKITGYIVERRE 19420

Query: 1485  TGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGD-SPASSKPISINYRTEID 1543
                   ++       ++   ++ L     Y   V+A       S  S     I  + +++
Sbjct: 19421 LPDGRWLKCNYTNIQETYFEVTELTEDQRYEFRVFARNAADSVSEPSESTGPIIVKDDVE 19480

Query: 1544  KPSQMQVTDVQDNSI--SVKWLPSSSPVTG--YRVTTTPKNG---PGPTKTKTAGPD-QT 1595
              P  M     +D  +  + + L  ++ + G    V +  K+G       +T+    D  T
Sbjct: 19481 PPRVMMDVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTDNHT 19540

Query: 1596  EMTIEGL--QPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKG--LAFTDVDVDSIKIA 1651
              +T++    + T +YV+++  +N +G     V   V +   P    L    +  +   ++
Sbjct: 19541 LLTVKDCIRRDTGQYVLTL--KNVAGTRSVAVNCKVLDKPGPPAGPLEINGLTAEKCSLS 19598

Query: 1652  WESPQ----GQVSRYRVTYSSPEDGIHELFPAPDGE--EDTAELQGLRPGSEYTVSVVAL 1705
             W  PQ      +  Y V      +  H  +   +GE    + ++  L  G+EY   V  +
Sbjct: 19599 WGRPQEDGGADIDYYIV---EKRETSHLAWTICEGELQMTSCKVTKLLKGNEYIFRVTGV 19655

Query: 1706  HDDMESQPLIGTQSTAIPA---------PTDLKFTQVTPTSLSAQWTPP----NVQLTGY 1752
             +     +PL   +S AI A         PT L+ T VT  S++  W+ P      +++GY
Sbjct: 19656 NKYGVGEPL---ESVAIKALDPFTVPSPPTSLEITSVTKESMTLCWSRPESDGGSEISGY 19712

Query: 1753  RVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQ--GVVTT 1810
              +    K     ++          V  +GL    +YE  VYA      S P++   ++  
Sbjct: 19713 IIERREKNSLRWVRVNKKPVYDLRVKSTGLREGCEYEYRVYAENAAGLSLPSETSPLIRA 19772

Query: 1811  LENV---SPPRRARVTDATETTITISWRTKT----ETITGFQVD---AVPANGQTPIQRT 1860
              + V   SPP + ++ D+ +TTITI+W          ITG+ V+   +   + +T IQ  
Sbjct: 19773 EDPVFLPSPPSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEYKKSDDTDWKTSIQSL 19832

Query: 1861  IKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSP 1894
                +   YTI+GL  G +Y   + ++N    S P
Sbjct: 19833 RGTE---YTISGLTTGAEYVFRVKSVNKVGASDP 19863



 Score =  120 bits (302), Expect = 1e-26
 Identities = 326/1553 (20%), Positives = 547/1553 (35%), Gaps = 248/1553 (15%)

Query: 605  YPSSSGPVEVFITETPSQPNSHPIQWNAPQ---PSHISKYILRWRPKNSVGRWKEA-TIP 660
            Y     P+ V IT+      S  + W  P+    + I+ Y++  R K S+ RW  A T+ 
Sbjct: 6883 YDVPGPPLNVTITDVNRFGVS--LTWEPPEYDGGAEITNYVIELRDKTSI-RWDTAMTVR 6939

Query: 661  GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP 720
                S T+       V EGQ  S +        R      S +TP        E  P  P
Sbjct: 6940 AEDLSATVTD-----VVEGQEYSFRVRAQN---RIGVGKPSAATPFVKVADPIER-PSPP 6990

Query: 721  LVATSESVTEITASSFVVSWV----SASDTVSGFRVEYELSEEGDEPQY---LDLPSTAT 773
            +  TS   T+   SS  + W          + G+ +E    EEG +      + L    T
Sbjct: 6991 VNLTSSDQTQ---SSVQLKWEPPLKDGGSPILGYIIER--CEEGKDNWIRCNMKLVPELT 7045

Query: 774  SVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQV---DDTSIVVR 830
               +  L  G KY+  V   ++ G           TA DA  +PT+D     D   ++V 
Sbjct: 7046 -YKVTGLEKGNKYLYRVSAENKAGVSDPSEILGPLTADDAFVEPTMDLSAFKDGLEVIV- 7103

Query: 831  WSRP---QAPITGYRIVYSPSVEGSSTELNLPETANSVTLSD-----LQPGVQYNITIYA 882
               P     P TGY    +    G    L   +     TLS      + P  + +  IY 
Sbjct: 7104 -PNPITILVPSTGYPRPTATWCFGDKV-LETGDRVKMKTLSAYAELVISPSERSDKGIYT 7161

Query: 883  VEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYR 938
            ++       +  + +     R     +P++L+F ++T   V + W PP+    S +TGY 
Sbjct: 7162 LKLENRVKTISGEIDVNVIARPS---APKELKFGDITKDSVHLTWEPPDDDGGSPLTGYV 7218

Query: 939  VDVIPVNLPGEHGQRLPISRNTFAE-----------VTGLSPGVTYYFKVFAVSHGRESK 987
            V            ++  +SR T+ +           V  L  G  Y FKV A +     +
Sbjct: 7219 V------------EKREVSRKTWTKVMDFVTDLEFTVPDLVQGKEYLFKVCARNKCGPGE 7266

Query: 988  PLTAQQTTKL-------DAPTNLQFVNETDSTVLVRWTPPR----AQITGYRLTVGLTRR 1036
            P    +   +       D P N+++ + T +++ + W PP+    ++I GY   V    R
Sbjct: 7267 PAYVDEPVNMSTPATVPDPPENVKWRDRTANSIFLTWDPPKNDGGSRIKGY--IVERCPR 7324

Query: 1037 GQPRQYNVGPSV--SKYPLRNLQPASEYTVSLVAIK-----------------GNQESPK 1077
            G  +    G  V  +K  +  L+    Y   + A+                    QE+P+
Sbjct: 7325 GSDKWVACGEPVAETKMEVTGLEEGKWYAYRVKALNRQGASKPSRPTEEIQAVDTQEAPE 7384

Query: 1078 ATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGF-KLGVRPSQGGEAPREVTSDSG 1136
               +F  ++  + +        E    +T  P P+I + K  +   Q      E      
Sbjct: 7385 ---IFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPKKS 7441

Query: 1137 SIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHL-EANPDTGVLTVSW 1195
            ++ +          Y I+ +       A +   V+    PP    + +   ++ +LT + 
Sbjct: 7442 TVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNVLDKPGPPAAFDITDVTNESCLLTWNP 7501

Query: 1196 ERST-TPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSV-----YT 1249
             R      IT Y +    T+ +  + L   V       T   L P  EY   V     Y 
Sbjct: 7502 PRDDGGSKITNYVVERRATDSEVWHKLSSTVKDTNFKAT--KLIPNKEYIFRVAAENMYG 7559

Query: 1250 VKDDKESVPISDTIIPAVP-PPTDLRFTNIGPDTMRVTWAPPP---SIDLTNFLVRYSPV 1305
            V +  ++ PI+       P PPT L  ++I  D + +TW  P       +T + V     
Sbjct: 7560 VGEPVQASPITAKYQFDPPGPPTRLEPSDITKDAVTLTWCEPDDDGGSPITGYWVERLDP 7619

Query: 1306 KNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGID 1365
              ++ V    +   D    +  L    +Y   V +        P +  +   +  P    
Sbjct: 7620 DTDKWVRCNKMPVKDTTYRVKGLTNKKKYRFRVLAENLAGPGKPSKSTEPILIKDPIDPP 7679

Query: 1366 F-------SDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPR-EDRVPHSRNSI 1413
            +        D+   S  ++W  P     A I  Y I           R  + VP +++  
Sbjct: 7680 WPPGKPTVKDVGKTSVRLNWTKPEHDGGAKIESYVIEMLKTGTDEWVRVAEGVPTTQH-- 7737

Query: 1414 TLTNLTPGTEYVVSIVALNGREES-------PLLIGQQSTVSDVPRDLEVVAATPTSLLI 1466
             L  L  G EY   + A+N   ES       P+L  ++      PR LEV+  T  +  +
Sbjct: 7738 LLPGLMEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLEVINITKNTADL 7797

Query: 1467 SWDAPAVTVRYYRITYGETGGNSPVQEFTVPG---------------SKSTATISGLKPG 1511
             W  P            E  G SP+  + V                   +  T++ L  G
Sbjct: 7798 KWTVP------------EKDGGSPITNYIVEKRDVRRKGWQTVDTTVKDTKCTVTPLTEG 7845

Query: 1512 VDYTITVYAVTGRGDSPASSKPISINYR---TEIDKPSQMQVTDVQDNSISVKWLPSSS- 1567
              Y   V A    G S  +    S+  +   T    P  + V DV    + +KW P  + 
Sbjct: 7846 SLYVFRVAAENAIGQSDYTEIEDSVLAKDTFTTPGPPYALAVVDVTKRHVDLKWEPPKND 7905

Query: 1568 ---PVTGYRVTTTPKNGPGPTKT-KTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQP 1623
               P+  Y +    + G    K  KTAGPD      + ++ T E    V A+N +G   P
Sbjct: 7906 GGRPIQRYVIEKKERLGTRWVKAGKTAGPDCNFRVTDVIEGT-EVQFQVRAENEAGVGHP 7964

Query: 1624 LVQTAVTNIDRPKG-------LAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHEL 1676
               T + +I+ P         L  TD     I IAW+ P+           SP  G H +
Sbjct: 7965 SEPTEILSIEDPTSPPSPPLDLHVTDAGRKHIAIAWKPPE-------KNGGSPIIGYH-V 8016

Query: 1677 FPAPDGEEDTAEL-------------QGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIP 1723
               P G E    +             +G+ P  EY + V A++    S+P   +++    
Sbjct: 8017 EMCPVGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAIGVSEPSEISENVVAK 8076

Query: 1724 APTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLM 1783
             P D K T    T          + + G ++ +    +  P+  ++   D   V  S  +
Sbjct: 8077 DP-DCKPTIDLETH-------DIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRL 8128

Query: 1784 VATKYEVSVYALKDTLTSRPAQGVVT-TLEN----------------VSPPRRARVTDAT 1826
                  +S + L+   + R   G+ T TLEN                  P +  + +D T
Sbjct: 8129 TMKNDHISAH-LEVPKSVRADAGIYTITLENKLGSATASINVKVIGLPGPCKDIKASDIT 8187

Query: 1827 ETTITISWRTKT----ETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIY 1882
            +++  ++W          I  + ++   A  +T I      +  S+T+  L P  +Y   
Sbjct: 8188 KSSCKLTWEPPEFDGGTPILHYVLERREAGRRTYIPVMSGENKLSWTVKDLIPNGEYFFR 8247

Query: 1883 LYTLND-------NARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPP----RARIT 1931
            +  +N          ++  +  D     D P ++     T  ++ ++W+PP     ++I 
Sbjct: 8248 VKAVNKVGGGEYIELKNPVIAQDPKQPPDPPVDVEVHNPTAEAMTITWKPPLYDGGSKIM 8307

Query: 1932 GYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEP 1984
            GYII+    G    +        +   T  GLE G EY   V A      SEP
Sbjct: 8308 GYIIEKIAKGEERWKRCNEHLVPILTYTAKGLEEGKEYQFRVRAENAAGISEP 8360



 Score =  118 bits (296), Expect = 6e-26
 Identities = 316/1543 (20%), Positives = 554/1543 (35%), Gaps = 238/1543 (15%)

Query: 607   SSSGPVEVFIT----ETPSQPNSHPIQWNAPQPSHISKYILRWRP---------KNSVGR 653
             +SSG    F+T    +TP  P +  ++      +      L W P         KN V  
Sbjct: 17794 NSSGSKSAFVTVKVLDTPGPPQNLAVKEVRKDSA-----FLVWEPPIIDGGAKVKNYVID 17848

Query: 654   WKEATIPGHLN--------SYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTP 705
              +E+T   + N        S+ ++ L  G +Y  ++++  ++G                P
Sbjct: 17849 KRESTRKAYANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFG-------------VGVP 17895

Query: 706   VTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVS----ASDTVSGFRVEYELSEEGD 761
             V +        P SP      ++T+++ +S  + W          V G+ VE  +  +G 
Sbjct: 17896 VETVDAVKAAEPPSP--PGKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVE--MQPKGT 17951

Query: 762   EPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQ 821
             E   +   S   +  +  L  G++Y   V   +E G+    +      A D    P++  
Sbjct: 17952 EKWSIVAESKVCNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKL 18011

Query: 822   VDDTSIVVRWS--RPQAPITGY-RIVYSPSVEGS----STELNLPETANSVTLSDLQPGV 874
               +T  +      + + P+ G  R   S   +G     +T +N+ ETA S  L  ++ G 
Sbjct: 18012 PFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLH-IKEGN 18070

Query: 875   QYNITIYAVEENQESTPV-----VIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTP 929
             + +   Y V     +        VI  E  G P          ++F EV+   V I W P
Sbjct: 18071 KDDFGKYTVTATNSAGTATENLSVIVLEKPGPPVGP-------VRFDEVSADFVVISWEP 18123

Query: 930   PESA----VTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRE 985
             P       ++ Y V+         H     ++R T  ++T L  G  Y F++FA +   +
Sbjct: 18124 PAYTGGCQISNYIVEKRDTTTTTWHMVSATVARTTI-KITKLKTGTEYQFRIFAENRYGK 18182

Query: 986   SKPLTA-----QQTTKLDAPTNLQFVNE-TDSTVLVRWTPP----RAQITGYRLTVGLTR 1035
             S PL +     Q   K   P    FV   +   +LV+W  P      +I GY L      
Sbjct: 18183 SAPLDSKAVIVQYPFKEPGPPGTPFVTSISKDQMLVQWHEPVNDGGTKIIGYHLEQKEKN 18242

Query: 1036  RGQPRQYNVGP-SVSKYPLRNLQPASEYT--VSLVAIKGNQESPKATGVFTTLQPGSSIP 1092
                  + N  P   +K+    L    EY   VS   I G  +  K +  F    P    P
Sbjct: 18243 SILWVKLNKTPIQDTKFKTTGLDEGLEYEFKVSAENIVGIGKPSKVSECFVARDPCD--P 18300

Query: 1093  PYNTE---VTETTIVITWT-PAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVE 1148
             P   E   +T   + + W  PA   G K+     +  + P       G  + +  T  +E
Sbjct: 18301 PGRPEAIVITRNNVTLKWKKPAYDGGSKITGYIVEKKDLP------DGRWMKASFTNVLE 18354

Query: 1149  YVYTIQVLRDGQERDAPIVNK-VVTPLSPPT---------------NLHLEANPDTGVLT 1192
               +T+  L + Q  +  ++ +      S P+               N  L+      ++ 
Sbjct: 18355 TEFTVSGLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARDEIDAPNASLDPKYKDVIVV 18414

Query: 1193  VSWERSTTP-DITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLS---------PGLE 1242
              + E      DI G  I     + + G  LEE     +   T    +          G +
Sbjct: 18415 HAGETFVLEADIRGKPIPDVVWS-KDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQ 18473

Query: 1243  YNVSVYTVKDDKESVPISDTIIPAVPPPTD-LRFTNIGPDTMRVTWAPPPSIDLTNFLVR 1301
             Y + +  V   K S+PI+  ++    PP   L+ T +  +   + W PP      N    
Sbjct: 18474 YILKLSNVGGTK-SIPITVKVLDRPGPPEGPLKVTGVTAEKCYLAWNPPLQDGGANISHY 18532

Query: 1302  YSPVKNEEDVAELSISPSDNAV--VLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLD 1359
                 +    ++   +S    A+   +T LLPG EY+  V +V +     PL     T  +
Sbjct: 18533 IIEKRETSRLSWTQVSTEVQALNYKVTKLLPGNEYIFRVMAVNKYGIGEPLESGPVTACN 18592

Query: 1360  ------SPTGIDFSDITANSFTVHWIAP----RATITGYRIRHHPEHFSGRPREDRVPHS 1409
                    P+  + S IT +S  V W  P       I GY +    +      + ++   +
Sbjct: 18593 PYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDKEGVRWTKCNKKTLT 18652

Query: 1410  RNSITLTNLTPGTEYVVSIVALN----GREESPLLIGQQSTV---SDVPRDLEVVAATPT 1462
                + +T LT G  Y   + A N    G    P +  +          P + +V   + +
Sbjct: 18653 DLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRACDALYPPGPPSNPKVTDTSRS 18712

Query: 1463  SLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTA-----------------TI 1505
             S+ ++W  P               G +PV+ + V   ++ A                 T+
Sbjct: 18713 SVSLAWSKPIY------------DGGAPVKGYVVEVKEAAADEWTTCTPPTGLQGKQFTV 18760

Query: 1506  SGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPS 1565
             + LK   +Y   + A+   G    ++ P S+  +  I+ P      D++     V  L +
Sbjct: 18761 TKLKENTEYNFRICAINSEGVGEPATLPGSVVAQERIEPPEIELDADLR----KVVVLRA 18816

Query: 1566  SSPVTGYRVTTTPKNGPGP----TKTKTAGPD--QTEMTIEGLQPTVEYVV-------SV 1612
             S+ +   R+  T K  P P     K +    D  Q E+T       ++ V        ++
Sbjct: 18817 SATL---RLFVTIKGRPEPEVKWEKAEGILTDRAQIEVTSSFTMLVIDNVTRFDSGRYNL 18873

Query: 1613  YAQNPSGESQPLVQTAVTNI-DRPKGLAFTDVDVDSIKIAWESP----QGQVSRYRVTYS 1667
               +N SG     V   V +    P  L   +V  DS+ ++WE P      +++ Y V   
Sbjct: 18874 TLENNSGSKTAFVNVRVLDSPSAPVNLTIREVKKDSVTLSWEPPLIDGGAKITNYIVEKR 18933

Query: 1668  SPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPT- 1726
                   +      +  + T  ++ L+ G  Y   V+A ++     P   T+   +  P  
Sbjct: 18934 ETTRKAYATI-TNNCTKTTFRIENLQEGCSYYFRVLASNEYGIGLPAETTEPVKVSEPPL 18992

Query: 1727  ---DLKFTQVTPTSLSAQWTPP----NVQLTGYRVRVTPK--EKTGPMKEINLAPDSSSV 1777
                 +    VT  + + +W  P      ++TGY V +  K  EK     ++     +   
Sbjct: 18993 PPGRVTLVDVTRNTATIKWEKPESDGGSKITGYVVEMQTKGSEKWSTCTQVK----TLEA 19048

Query: 1778  VVSGLMVATKYEVSVYALKDTLTSRPAQ-GVVTTLENVS-------PPRRARVTDATETT 1829
              +SGL    +Y   V A+ +   S P Q GV     ++        P     V    +  
Sbjct: 19049 TISGLTAGEEYVFRVAAVNEKGRSDPRQLGVPVIARDIEIKPSVELPFHTFNVKAREQLK 19108

Query: 1830  ITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQ----PGTDYKIYLYT 1885
             I + ++ + +    ++ D     GQT  + T      S T+T L        D   Y   
Sbjct: 19109 IDVPFKGRPQATVNWRKD-----GQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELC 19163

Query: 1886  LNDNARS--SPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEK 1939
             ++++A S   P+ I        P  +R    + +S+ +SW PP      +I+ YI++ ++
Sbjct: 19164 VSNSAGSITVPITIIVLDRPGPPGPIRIDEVSCDSITISWNPPEYDGGCQISNYIVEKKE 19223

Query: 1940  PGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKS 1982
               S    +V +     T   I  L  G+EY   V A     KS
Sbjct: 19224 TTSTTWHIVSQ-AVARTSIKIVRLTTGSEYQFRVCAENRYGKS 19265



 Score =  118 bits (295), Expect = 8e-26
 Identities = 287/1359 (21%), Positives = 491/1359 (36%), Gaps = 205/1359 (15%)

Query: 780   LLPGRKYI-----VNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRP 834
             ++ G +YI     VN Y I E  E   +++ +    P  P  P V ++   S+ V WSRP
Sbjct: 20725 IIKGNEYIFRVRAVNKYGIGEPLESDSVVAKNAFVTPGPPGIPEVTKITKNSMTVVWSRP 20784

Query: 835   QA----PITGYRIVYSPSVEGSSTEL---NLPETANSVTLSDLQPGVQYNI-TIYAVEEN 886
              A     I+GY +           ++    + +T   VT        QY +  + A  + 
Sbjct: 20785 IADGGSDISGYFLEKRDKKSLGWFKVLKETIRDTRQKVTGLTENSDYQYRVCAVNAAGQG 20844

Query: 887   QESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVI 942
               S P    +        D    P  ++  + T   +T+ W+ P     SAVTGY V++ 
Sbjct: 20845 PFSEP---SEFYKAADPIDPPGPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVVEI- 20900

Query: 943   PVNLPGEHGQRLPIS-----RNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTK- 996
                  GE  +   +S     R T   V+ L PGV YYF+V AV+   + +P+   +  + 
Sbjct: 20901 ---RQGEEEEWTTVSTKGEVRTTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQA 20957

Query: 997   ---LDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQP--------RQYNVG 1045
                L+AP       E D  V +R T   A+  G  + V +  +G+P         + N+G
Sbjct: 20958 KDILEAP-------EIDLDVALR-TSVIAK-AGEDVQVLIPFKGRPPPTVTWRKDEKNLG 21008

Query: 1046  PSVSKYPLRNLQPASEYTVS----------LVAIKGNQESPKATGVFTTL--QPGSSIPP 1093
              S ++Y + N   +S  T+           ++ I+     PK++ V   +   P +    
Sbjct: 21009 -SDARYSIENTDSSSLLTIPQVTRNDTGKYILTIENGVGEPKSSTVSVKVLDTPAACQKL 21067

Query: 1094  YNTEVTETTIVITWTP------APRIGFKLGVRPS---QGGEAPREVTSDSGSIV-VSGL 1143
                 V+  T+ + W P      +P I + +  R +          + +S S  ++ +S  
Sbjct: 21068 QVKHVSRGTVTLLWDPPLIDGGSPIINYVIEKRDATKRTWSVVSHKCSSTSFKLIDLSEK 21127

Query: 1144  TPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDI 1203
             TP    V     +  G+  +     K     +P  +L ++ +  T V+ +SW   T PD 
Sbjct: 21128 TPFFFRVLAENEIGIGEPCETTEPVKAAEVPAPIRDLSMKDSTKTSVI-LSW---TKPDF 21183

Query: 1204  TGYRITTTPTNGQQGNSLEEVVHADQS-SCTFD----NLSPGLEYNVSVYTVKDDKESVP 1258
              G  + T     ++G   +   HA  S +C  +         LE+ V     K   + V 
Sbjct: 21184 DGGSVITEYVVERKGKGEQTWSHAGISKTCEIEVSQLKEQSVLEFRVFAKNEKGLSDPVT 21243

Query: 1259  ISDTIIP--AVPPPTDLRFTNIGPDTMRV----------TWAPPPSIDLTNFLVRYSPVK 1306
             I    +    + P  DL        T+R+             P PSI   ++L    P+K
Sbjct: 21244 IGPITVKELIITPEVDLSDIPGAQVTVRIGHNVHLELPYKGKPKPSI---SWLKDGLPLK 21300

Query: 1307  NEEDVAELSISPSDNAVVLT----NLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPT 1362
               E V     S ++N + L+        G +Y V + +      + P+          P 
Sbjct: 21301 ESEFV---RFSKTENKITLSIKNAKKEHGGKYTVILDNAV-CRIAVPITVITLGPPSKPK 21356

Query: 1363  G-IDFSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTN 1417
             G I F +I A+S  + W  P       IT Y I    E      +      +R +  + N
Sbjct: 21357 GPIRFDEIKADSVILSWDVPEDNGGGEITCYSIEKR-ETSQTNWKMVCSSVARTTFKVPN 21415

Query: 1418  LTPGTEYVVSIVALNGREESPLLIG------QQSTVSDVPRDLEVVAATPTSLLISWDAP 1471
             L    EY   + A N    S  L+        Q  +   P    +   T   + ++WDAP
Sbjct: 21416 LVKDAEYQFRVRAENRYGVSQPLVSSIIVAKHQFRIPGPPGKPVIYNVTSDGMSLTWDAP 21475

Query: 1472  AV----TVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDS 1527
                    V  + +   E       +  T P S      +GL  G+DY   VYA    G S
Sbjct: 21476 VYDGGSEVTGFHVEKKERNSILWQKVNTSPISGREYRATGLVEGLDYQFRVYAENSAGLS 21535

Query: 1528  PASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLP----SSSPVTGYRVTTTPKNGPG 1583
               S         + +D P      DV   +I++KW P      S + GY +     N   
Sbjct: 21536 SPSDPSKFTLAVSPVDPPGTPDYIDVTRETITLKWNPPLRDGGSKIVGYSIEKRQGNERW 21595

Query: 1584  PTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQN------PSGESQPLVQTAVTNIDRPKG 1637
               +       + + T+ GL P   Y   + A+N      P  +S  ++ T   N+  P  
Sbjct: 21596 -VRCNFTDVSECQYTVTGLSPGDRYEFRIIARNAVGTISPPSQSSGIIMTRDENV--PPI 21652

Query: 1638  LAFTDVDVDSI--------------------KIAWESPQGQVSRYRVTYSSPEDGIHELF 1677
             + F     D +                    ++ W     ++ +      +   G   LF
Sbjct: 21653 VEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLF 21712

Query: 1678  PAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTS 1737
                   + T + +G+     YTV         +++  +  Q T       ++FT +T   
Sbjct: 21713 V----RDATRDHRGV-----YTVEAKNASGSAKAEIKVKVQDTPGKVVGPIRFTNITGEK 21763

Query: 1738  LSAQWTPP-NVQLTGYRVRVTPKEKTGPM--KEINLAPDSSSVVVSGLMVATKYEVSVYA 1794
             ++  W  P N         +  K +T  +    I    ++ S     L+   +Y+  V A
Sbjct: 21764 MTLWWDAPLNDGCAPITHYIIEKRETSRLAWALIEDKCEAQSYTAIKLINGNEYQFRVSA 21823

Query: 1795  LKDTLTSRP--AQGVVTTLENVSP--PRRARVTDATETTITISWRTKTETITGFQVDA-- 1848
             +      RP  +  VV  ++   P  P     ++ T  +IT++W  + E+  G ++    
Sbjct: 21824 VNKFGVGRPLDSDPVVAQIQYTVPDAPGIPEPSNITGNSITLTW-ARPESDGGSEIQQYI 21882

Query: 1849  -----------VPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVI 1897
                        V    + PI  T       + +TGL  G +Y+ ++  + +NA       
Sbjct: 21883 LERREKKSTRWVKVISKRPISET------RFKVTGLTEGNEYEFHV--MAENAAGVGPAS 21934

Query: 1898  DASTAIDA---------PSNLRFLATTPNSLLVSWQPP----RARITGYIIKYEKPGSPP 1944
               S  I           P+ ++   T+  ++ + W  P       I GYII+  K     
Sbjct: 21935 GISRLIKCREPVNPPGPPTVVKVTDTSKTTVSLEWSKPVFDGGMEIIGYIIEMCKADLGD 21994

Query: 1945  REVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSE 1983
                V       T  T+T L+ G EY   V A+    K +
Sbjct: 21995 WHKVNAEACVKTRYTVTDLQAGEEYKFRVSAINGAGKGD 22033



 Score =  117 bits (294), Expect = 1e-25
 Identities = 275/1247 (22%), Positives = 460/1247 (36%), Gaps = 215/1247 (17%)

Query: 908   PSP-RDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTG 966
             P P R+L+ V+V+  + T+ W PPE    G  +     N   E  +   +  +T++  T 
Sbjct: 11992 PGPVRNLKIVDVSSDRCTVCWDPPEDD-GGCEIQ----NYILEKCETKRMVWSTYS-ATV 12045

Query: 967   LSPGVT---------YYFKVFA-----VSHGRESKPLTAQQTTKLDA-----PTNLQFVN 1007
             L+PG T         Y F+V A          ESKP+ A+  TK D      P  +  V+
Sbjct: 12046 LTPGTTVTRLIEGNEYIFRVRAENKIGTGPPTESKPVIAK--TKYDKPGRPDPPEVTKVS 12103

Query: 1008  ETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSV---SKYPLRNLQPAS 1060
             + + TV+  W PP       ITGY L      +   R   V  S     +  ++NL P  
Sbjct: 12104 KEEMTVV--WNPPEYDGGKSITGYFLE--KKEKHSTRWVPVNKSAIPERRMKVQNLLPDH 12159

Query: 1061  EYTVSLVAIK----GNQESPKATGVF-TTLQPGSSIPPYNTEVTETT---IVITWTP--- 1109
             EY   + A      G    P    V    ++P    PP N  V +TT   I + W     
Sbjct: 12160 EYQFRVKAENEIGIGEPSLPSRPVVAKDPIEPPG--PPTNFRVVDTTKHSITLGWGKPVY 12217

Query: 1110  ---APRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPI 1166
                AP IG+ + +RP     +P     D G    +     V   +T+  L + QE +  +
Sbjct: 12218 DGGAPIIGYVVEMRPKIADASP-----DEGWKRCNAAAQLVRKEFTVTSLDENQEYEFRV 12272

Query: 1167  VNKVVTPLSPPTNLHLEANP-----------DTGVLTVSWERSTTPD--ITGYRITTTPT 1213
               +    +  P  L     P           D  +  +   R+  P       R    P 
Sbjct: 12273 CAQNQVGIGRPAELKEAIKPKEILEPPEIDLDASMRKLVIVRAGCPIRLFAIVRGRPAPK 12332

Query: 1214  NGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDD-------------KESVPIS 1260
                +   ++ VV   Q      +L   + + V   + +DD             +++V ++
Sbjct: 12333 VTWRKVGIDNVVRKGQV-----DLVDTMAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFVN 12387

Query: 1261  DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELS-ISP- 1318
               ++    P +DL+ +++   +  V+WAPP + D  + +  Y   K E D    S ++P 
Sbjct: 12388 VRVLDTPGPVSDLKVSDVTKTSCHVSWAPPEN-DGGSQVTHYIVEKREADRKTWSTVTPE 12446

Query: 1319  -SDNAVVLTNLLPGTEYVVSVSSVYEQHESTP-------LRGRQKTGLDSPTGIDFSDIT 1370
                 +  +TNL+PG EY   V++V E     P       L     +  D P  ++ +++T
Sbjct: 12447 VKKTSFHVTNLVPGNEYYFRVTAVNEYGPGVPTDVPKPVLASDPLSEPDPPRKLEVTEMT 12506

Query: 1371  ANSFTVHWIAP----RATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVV 1426
              NS T+ W+ P     A I GY   +  E        +       S+ +T L  G +Y  
Sbjct: 12507 KNSATLAWLPPLRDGGAKIDGYITSYREEEQPADRWTEYSVVKDLSLVVTGLKEGKKYKF 12566

Query: 1427  SIVALNGREESPLLIGQQSTVSDVPRDLEVV-----AATPTSLLISWDAPAVTVRYYRIT 1481
              + A N    S            +PR+ E V        P  +L+         +  RI 
Sbjct: 12567 RVAARNAVGVS------------LPREAEGVYEAKEQLLPPKILMPEQITIKAGKKLRIE 12614

Query: 1482  YGETGGNSPV------QEFTVPGS------KSTATISGLKPGVDYTITVYAVTGRGDSPA 1529
                 G   P       ++  V  S        +++I  +K         Y++T    S  
Sbjct: 12615 AHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGYYSLTAENSSGT 12674

Query: 1530  SSKPISINYRTEIDKPSQMQ----VTDVQDNSISVKW-LP---SSSPVTGYRVTTTPKNG 1581
              ++ I +     +D P   Q    ++D+  ++ S+ W +P     S +T Y V     + 
Sbjct: 12675 DTQKIKV---VVMDAPGPPQPPFDISDIDADACSLSWHIPLEDGGSNITNYIVEKCDVS- 12730

Query: 1582  PGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTN------IDRP 1635
              G   T  A   +T   +  L P  EY+  V A+N  G S+PL    +           P
Sbjct: 12731 RGDWVTALASVTKTSCRVGKLIPGQEYIFRVRAENRFGISEPLTSPKMVAQFPFGVPSEP 12790

Query: 1636  KGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELF--PAPDGEEDTAE--LQG 1691
             K    T V+ D I +AW+ P        + Y       + L    A D    + E    G
Sbjct: 12791 KNARVTKVNKDCIFVAWDRPDSDGGSPIIGYLIERKERNSLLWVKANDTLVRSTEYPCAG 12850

Query: 1692  LRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTD----LKFTQVTPTSLSAQWTPP-- 1745
             L  G EY+  + AL+    S P   T+      P D     +   VT +++S  W  P  
Sbjct: 12851 LVEGLEYSFRIYALNKAGSSPPSKPTEYVTARMPVDPPGKPEVIDVTKSTVSLIWARPKH 12910

Query: 1746  --NVQLTGYRVRVTPKEKTGPMKEINLAP---DSSSVVVSGLMVATKYE---VSVYALKD 1797
                 ++ GY V    K         N AP          +GL    +Y+   ++  A+  
Sbjct: 12911 DGGSKIIGYFVEAC-KLPGDKWVRCNTAPHQIPQEEYTATGLEEKAQYQFRAIARTAVNI 12969

Query: 1798  TLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKT---ETITGFQVDAV----- 1849
             +  S P+  V    ENV P  R  ++ A ++ +T+   T      T+ G  +  V     
Sbjct: 12970 SPPSEPSDPVTILAENVPP--RIDLSVAMKSLLTVKAGTNVCLDATVFGKPMPTVSWKKD 13027

Query: 1850  -----PANG-QTPIQRTI---------KPDVRSYTITGLQPGTDYKIYLYTLNDNARSSP 1894
                  PA G +  +QR +         + D   YTIT               +  ++S+ 
Sbjct: 13028 GTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTITAEN------------SSGSKSAT 13075

Query: 1895  VVIDASTAIDAPSNLRFLATTPNSLLVSWQPP----RARITGYIIKYEKPGSPPREVVPR 1950
             + +        P++++      +  ++SW+PP     + IT YI+   +   P    V  
Sbjct: 13076 IKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYIVDKRETSRPNWAQVSA 13135

Query: 1951  PRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQKTPF 1997
               P +T  ++  L  G EY   + A       +P+   +  + K P+
Sbjct: 13136 TVP-ITSCSVEKLIEGHEYQFRICAENKYGVGDPVF-TEPAIAKNPY 13180



 Score =  117 bits (293), Expect = 1e-25
 Identities = 324/1541 (21%), Positives = 541/1541 (35%), Gaps = 222/1541 (14%)

Query: 612  VEVFITETPSQPNSHPIQ----------WNAPQP---SHISKYILRWRPKNSVGRWKEAT 658
            VEV + + P  P +  I           WN P+    S I+ Y++  R  +S   W + +
Sbjct: 7471 VEVNVLDKPGPPAAFDITDVTNESCLLTWNPPRDDGGSKITNYVVERRATDSEV-WHKLS 7529

Query: 659  IPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPF 718
                  ++    L P   Y  ++ +   YG  E             PV ++ +T +    
Sbjct: 7530 STVKDTNFKATKLIPNKEYIFRVAAENMYGVGE-------------PVQASPITAKYQFD 7576

Query: 719  SPLVATSESVTEITASSFVVSWVSASDT----VSGFRVEYELSEEGDEPQYLDLPSTATS 774
             P   T    ++IT  +  ++W    D     ++G+ VE    +     +   +P   T+
Sbjct: 7577 PPGPPTRLEPSDITKDAVTLTWCEPDDDGGSPITGYWVERLDPDTDKWVRCNKMPVKDTT 7636

Query: 775  VNIPDLLPGRKYIVNVY--QISEDGEQSL----ILSTSQTTAPDAPPDPTVDQVDDTSIV 828
              +  L   +KY   V    ++  G+ S     IL       P  P  PTV  V  TS+ 
Sbjct: 7637 YRVKGLTNKKKYRFRVLAENLAGPGKPSKSTEPILIKDPIDPPWPPGKPTVKDVGKTSVR 7696

Query: 829  VRWSRPQ----APITGY--RIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYA 882
            + W++P+    A I  Y   ++ + + E       +P T +   L  L  G +Y+  + A
Sbjct: 7697 LNWTKPEHDGGAKIESYVIEMLKTGTDEWVRVAEGVPTTQH--LLPGLMEGQEYSFRVRA 7754

Query: 883  VEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYR 938
            V +  ES P           +      PR L+ + +T     + WT PE    S +T Y 
Sbjct: 7755 VNKAGESEPSEPSDPVLCREKLYPPSPPRWLEVINITKNTADLKWTVPEKDGGSPITNYI 7814

Query: 939  VDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSH-GR------ESKPLTA 991
            V+   V   G       + ++T   VT L+ G  Y F+V A +  G+      E   L  
Sbjct: 7815 VEKRDVRRKGWQTVDTTV-KDTKCTVTPLTEGSLYVFRVAAENAIGQSDYTEIEDSVLAK 7873

Query: 992  QQTTKLDAPTNLQFVNETDSTVLVRWTPPR--AQITGYRLTVGLTRRGQPRQYNVGPSVS 1049
               T    P  L  V+ T   V ++W PP+        R  +    R   R    G +  
Sbjct: 7874 DTFTTPGPPYALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKERLGTRWVKAGKTAG 7933

Query: 1050 KYPLRNLQPASEYTVSLVAIKGNQES-----PKATGVFTTLQPGS-SIPPYNTEVTET-- 1101
                  +    E T     ++   E+      + T + +   P S   PP +  VT+   
Sbjct: 7934 PDCNFRVTDVIEGTEVQFQVRAENEAGVGHPSEPTEILSIEDPTSPPSPPLDLHVTDAGR 7993

Query: 1102 -TIVITWTP------APRIGFKLGVRPSQGGEAPREVTS----DSGSIVVSGLTPGVEYV 1150
              I I W P      +P IG+ + + P  G E    V S    D    V  G+ P  EYV
Sbjct: 7994 KHIAIAWKPPEKNGGSPIIGYHVEMCP-VGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYV 8052

Query: 1151 YTIQVLRD-GQERDAPIVNKVVT--PLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYR 1207
              ++ +   G    + I   VV   P   PT + LE +    ++ +  E+ + P    +R
Sbjct: 8053 LRVRAVNAIGVSEPSEISENVVAKDPDCKPT-IDLETH---DIIVIEGEKLSIP--VPFR 8106

Query: 1208 ITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEY------NVSVYTV----KDDKESV 1257
                PT     +  +EV  +D+ +   D++S  LE       +  +YT+    K    + 
Sbjct: 8107 AVPVPTVSWHKDG-KEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATA 8165

Query: 1258 PISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSIS 1317
             I+  +I    P  D++ ++I   + ++TW PP     T  L      +       + + 
Sbjct: 8166 SINVKVIGLPGPCKDIKASDITKSSCKLTWEPPEFDGGTPILHYVLERREAGRRTYIPVM 8225

Query: 1318 PSDNAVVLT--NLLPGTEYVVSVSSV-------YEQHESTPLRGRQKTGLDSPTGIDFSD 1368
              +N +  T  +L+P  EY   V +V       Y + ++  +    K   D P  ++  +
Sbjct: 8226 SGENKLSWTVKDLIPNGEYFFRVKAVNKVGGGEYIELKNPVIAQDPKQPPDPPVDVEVHN 8285

Query: 1369 ITANSFTVHWIAP----RATITGYRIRH--HPEHFSGRPREDRVPHSRNSITLTNLTPGT 1422
             TA + T+ W  P     + I GY I      E    R  E  VP    + T   L  G 
Sbjct: 8286 PTAEAMTITWKPPLYDGGSKIMGYIIEKIAKGEERWKRCNEHLVPIL--TYTAKGLEEGK 8343

Query: 1423 EYVVSIVALNGREESPLLIGQQSTVSDVPRDL-EVVAATPTSLL----ISWDAPAVTVRY 1477
            EY   + A N    S        T +  P D  +V+  T   +     I+ DA      Y
Sbjct: 8344 EYQFRVRAENAAGISEPSRATPPTKAVDPIDAPKVILRTSLEVKRGDEIALDASISGSPY 8403

Query: 1478 YRITY------------------------GETGGNSP-----VQEFTVPGSKSTATISGL 1508
              IT+                        GE     P      Q  ++  SK   +   +
Sbjct: 8404 PTITWIKDENVIVPEEIKKRAAPLVRRRKGEVQEEEPFVLPLTQRLSIDNSKKGESQLRV 8463

Query: 1509 KPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLP---- 1564
            +  +     +Y +    D   +  P +++       P      D++  S+  KW P    
Sbjct: 8464 RDSLRPDHGLYMIKVENDHGIAKAPCTVSVLDTPGPPINFVFEDIRKTSVLCKWEPPLDD 8523

Query: 1565 SSSPVTGYRVTTTPKNGP-GPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQP 1623
              S +  Y +    K  P       T+     + ++  L    EY+  V A+N  G   P
Sbjct: 8524 GGSEIINYTLEKKDKTKPDSEWIVVTSTLRHCKYSVTKLIEGKEYLFRVRAENRFGPGPP 8583

Query: 1624 LVQTAVT------NIDRPKGLAFTDVDVDSIKIAWESPQ-------GQVSRYRVTYSSPE 1670
             V   +         D P      DV  +S+ + W  P+       G     R   S+  
Sbjct: 8584 CVSKPLVAKDPFGPPDAPDKPIVEDVTSNSMLVKWNEPKDNGSPILGYWLEKREVNSTHW 8643

Query: 1671 DGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHD------DMESQPLIGTQSTAIPA 1724
              +++           A + GL  G  Y   V A +          S P       + P 
Sbjct: 8644 SRVNKSLL----NALKANVDGLLEGLTYVFRVCAENAAGPGKFSPPSDPKTAHDPISPPG 8699

Query: 1725 PTDLKFTQVTPTSLSAQWTPP----NVQLTGYRVRVTPKEKTGPMKEINLAPDSSSV--- 1777
            P   + T  + T++  +W PP      ++ GY V    K+  G  +          V   
Sbjct: 8700 PPIPRVTDTSSTTIELEWEPPAFNGGGEIVGYFV---DKQLVGTNEWSRCTEKMIKVRQY 8756

Query: 1778 VVSGLMVATKYEVSVYALKDTLTSRPAQ-GVVTTLENVSPPRRARVTDATETTITISWRT 1836
             V  +     Y++ V A+       P +   VT  E   PP       A E  +++    
Sbjct: 8757 TVKEIREGADYKLRVSAVNAAGEGPPGETQPVTVAEPQEPP-------AVELDVSVKGGI 8809

Query: 1837 KTETITGFQVDAVPANGQTPIQRTIKPD--------------VRSYTITGLQPGTDYKIY 1882
            +       ++ AV      P +   K +               +S  I       D+  Y
Sbjct: 8810 QIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKDRVVIDNVGTKSELIIKDALRKDHGRY 8869

Query: 1883 LYTLNDNARSSPVVIDASTAIDAPS---NLRFLATTPNSLLVSWQPPR----ARITGYII 1935
            + T   N+  S          D P    +L+ + T     L++W  P     + ITG+II
Sbjct: 8870 VITAT-NSCGSKFAAARVEVFDVPGPVLDLKPVVTNRKMCLLNWSDPEDDGGSEITGFII 8928

Query: 1936 KYEKPGSPP-REVVPRPRPGVTEATITGLEPGTEYTIYVIA 1975
            + +       R+ +   R   ++  ITGL  G EY   VIA
Sbjct: 8929 ERKDAKMHTWRQPIETER---SKCDITGLLEGQEYKFRVIA 8966



 Score =  117 bits (293), Expect = 1e-25
 Identities = 292/1326 (22%), Positives = 488/1326 (36%), Gaps = 202/1326 (15%)

Query: 811   PDAPPDPT-VDQVDDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSV 865
             P  P  P   + V    + + W  P+    + IT Y I    +   +   ++      + 
Sbjct: 9912  PGPPVGPIKFESVSADQMTLSWFPPKDDGGSKITNYVIEKREANRKTWVHVSSEPKECTY 9971

Query: 866   TLSDLQPGVQYNITIYAVEENQESTPVVIQQETT-------GTPRSDTVPSPRDLQFVEV 918
             T+  L  G +Y   I A  +     P+  + ET        G P   TV S        V
Sbjct: 9972  TIPKLLEGHEYVFRIMAQNKYGIGEPLDSEPETARNLFSVPGAPDKPTVSS--------V 10023

Query: 919   TDVKVTIMWTPPE----SAVTGYRVDVIPVNLPG-EHGQRLPISRNTFA---EVTGLSPG 970
             T   +T+ W  PE    S VTGY +++        +   R PI   T     +VTGL  G
Sbjct: 10024 TRNSMTVNWEEPEYDGGSPVTGYWLEMKDTTSKRWKRVNRDPIKAMTLGVSYKVTGLIEG 10083

Query: 971   VTYYFKVFAVSHGR------ESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPR--- 1021
               Y F+V+A++          S P TA+       P   +  + T S+  + W+PP    
Sbjct: 10084 SDYQFRVYAINAAGVGPASLPSDPATARDPIAPPGPPFPKVTDWTKSSADLEWSPPLKDG 10143

Query: 1022  -AQITGYRLTVGLTRRGQPRQYNVGPSV----SKYPLRNLQPASEYT--VSLVAIKGNQE 1074
              +++TGY   V     G+  ++  G       +K  +  L+  + Y   V  V I G  E
Sbjct: 10144 GSKVTGY--IVEYKEEGK-EEWEKGKDKEVRGTKLVVTGLKEGAFYKFRVRAVNIAGIGE 10200

Query: 1075  SPKATGVFTT--------LQPGSSIPP----YNTEVTETTIVITWTPAPRIGFKLGVRPS 1122
               + T V           LQ  +S+      +   V      ++  P P + + +  R +
Sbjct: 10201 PGEVTDVIEMKDRLVSPDLQLDASVRDRIVVHAGGVIRIIAYVSGKPPPTVTWNMNER-T 10259

Query: 1123  QGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVT---PLSPPTN 1179
                EA  E T+ S S+V+       + VY++    +  ER   I+  V+    P+  P  
Sbjct: 10260 LPQEATIETTAISSSMVIKNCQRSHQGVYSLLAKNEAGERKKTIIVDVLDVPGPVGTPFL 10319

Query: 1180  LHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSP 1239
              H   N    +   S E      IT Y I    ++ +    +   V   + + T   L  
Sbjct: 10320 AHNLTNESCKLTWFSPEDDGGSPITNYVIEKRESDRRAWTPVTYTV--TRQNATVQGLIQ 10377

Query: 1240  GLEY--------NVSVYTVKDDKESVPISDTIIPAVPP-PTDLRFTNIGPDTMRVTWAPP 1290
             G  Y        ++ +    +  E++ I + I   VP  P DL    +  +T+ +TW PP
Sbjct: 10378 GKAYFFRIAAENSIGMGPFVETSEALVIREPI--TVPERPEDLEVKEVTKNTVTLTWNPP 10435

Query: 1291  P---SIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHES 1347
                   ++ N+++    +  E+     + +       +  L  G  Y   VS+V    + 
Sbjct: 10436 KYDGGSEIINYVLESRLIGTEKFHKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQG 10495

Query: 1348  TPLRGRQ----KTGLDSPT-GIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPR 1402
              P    +    K  L  PT  +DF D      T+  +     +TG         +SG+P+
Sbjct: 10496 KPSFCTKPITCKDELAPPTLHLDFRD----KLTIR-VGEAFALTG--------RYSGKPK 10542

Query: 1403  ------EDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQST--------VS 1448
                   +D      +  T    TP T  +  I A         ++ + ST        V+
Sbjct: 10543 PKVSWFKDEADVLEDDRTHIKTTPATLALEKIKAKRSDSGKYCVVVENSTGSRKGFCQVN 10602

Query: 1449  DVPRDLEVVA------ATPTSLLISWDAP----AVTVRYYRITYGETGGN--SPVQEFTV 1496
              V R    V        T   ++ISW  P       +  Y I   E G +   PV   T 
Sbjct: 10603 VVDRPGPPVGPVSFDEVTKDYMVISWKPPLDDGGSKITNYIIEKKEVGKDVWMPV---TS 10659

Query: 1497  PGSKSTATISGLKPGVDYTITVYAVTGRGDS-PASSKPISINYRTEI-DKPSQMQVTDVQ 1554
               +K+T  +S L  G DY   ++A    G S P  S  +    R  + D P Q  VT+V 
Sbjct: 10660 ASAKTTCKVSKLLEGKDYIFRIHAENLYGISDPLVSDSMKAKDRFRVPDAPDQPIVTEVT 10719

Query: 1555  DNSISVKWLP---SSSPVTGY---RVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEY 1608
              +S  V W        P+T Y   +  T  K     TK        T+  +  L    +Y
Sbjct: 10720 KDSALVTWNKPHDGGKPITNYILEKRETMSKRWARVTKDPIH--PYTKFRVPDLLEGCQY 10777

Query: 1609  VVSVYAQN------PSGESQPL-VQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQ----G 1657
                V A+N      PS  S+P+  +  +     P      D   +S+ + W+ P+     
Sbjct: 10778 EFRVSAENEIGIGDPSPPSKPVFAKDPIAKPSPPVNPEAIDTTCNSVDLTWQPPRHDGGS 10837

Query: 1658  QVSRYRVTYSSPEDGI-HELFPAPDGEEDTA-ELQGLRPGSEYTVSVVALHDDMESQPLI 1715
             ++  Y V Y    D         P+   +T  ++ GLR G  Y   V+A++   ES P  
Sbjct: 10838 KILGYIVEYQKVGDEEWRRANHTPESCPETKYKVTGLRDGQTYKFRVLAVNAAGESDP-- 10895

Query: 1716  GTQSTAIPAPTDLKFTQVTP-TSLSAQWTPPNVQLTGYRVRVT------PKEKTGPMKEI 1768
                   +P P  +K     P   L A          G  +R++      P  K    KE 
Sbjct: 10896 ----AHVPEPVLVKDRLEPPELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKED 10951

Query: 1769  NLAPDSSSVVVSGLMVATKYEV--------SVYAL--KDTLTSRPAQGVVTTLENVSPPR 1818
               AP  + + V+   V +K E+         +Y+L  ++   S+     V  L+   PPR
Sbjct: 10952 RDAPTKARIDVT--PVGSKLEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDKPGPPR 11009

Query: 1819  RARVTDATETTITISWRTKTE----TITGFQVDA--VPANGQTPIQRTIKPDVRSYTITG 1872
                V++  + +  ++W+   +     IT + V+   V +   +P+  T K   +S+    
Sbjct: 11010 DLEVSEIRKDSCYLTWKEPLDDGGSVITNYVVERRDVASAQWSPLSATSKK--KSHFAKH 11067

Query: 1873  LQPGTDYKIYLYTLNDNARSSPV-------VIDASTAIDAPSNLRFLATTPNSLLVSWQP 1925
             L  G  Y   +   N   R   V        +D       P +L  +      + + W  
Sbjct: 11068 LNEGNQYLFRVAAENQYGRGPFVETPKPIKALDPLHPPGPPKDLHHVDVDKTEVSLVWNK 11127

Query: 1926  P----RARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQK 1981
             P     + ITGY+++Y++ G+  ++ +        E  +TGL+ G  Y   V       K
Sbjct: 11128 PDRDGGSPITGYLVEYQEEGT--QDWIKFKTVTNLECVVTGLQQGKTYRFRV-------K 11178

Query: 1982  SEPLIG 1987
             +E ++G
Sbjct: 11179 AENIVG 11184



 Score =  114 bits (286), Expect = 9e-25
 Identities = 268/1373 (19%), Positives = 504/1373 (36%), Gaps = 176/1373 (12%)

Query: 766  LDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDT 825
            +D  +  TS  I +   G K    +   ++ G+    ++      P    +  V +  D 
Sbjct: 6740 IDTTAEQTSFRILEAKKGDKGRYKIVLQNKHGKAEGFINLKVIDVPGPVRNLEVTETFDG 6799

Query: 826  SIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETAN-SVTLSDLQPG-VQYNIT 879
             + + W  P     + I GY +V    ++  +  L      +   T++ LQ G V+Y   
Sbjct: 6800 EVSLAWEEPLTDGGSKIIGY-VVERRDIKRKTWVLATDRAESCEFTVTGLQKGGVEYLFR 6858

Query: 880  IYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVT 935
            + A        PV          + D    P ++   +V    V++ W PPE    + +T
Sbjct: 6859 VSARNRVGTGEPVETDNPVEARSKYDVPGPPLNVTITDVNRFGVSLTWEPPEYDGGAEIT 6918

Query: 936  GYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTT 995
             Y +++               + +  A VT +  G  Y F+V A +     KP  A    
Sbjct: 6919 NYVIELRDKTSIRWDTAMTVRAEDLSATVTDVVEGQEYSFRVRAQNRIGVGKPSAATPFV 6978

Query: 996  KL-------DAPTNLQFVNETDSTVLVRWTPP----RAQITGYRLTVGLTRRGQPR---- 1040
            K+         P NL   ++T S+V ++W PP     + I GY   +     G+      
Sbjct: 6979 KVADPIERPSPPVNLTSSDQTQSSVQLKWEPPLKDGGSPILGY--IIERCEEGKDNWIRC 7036

Query: 1041 QYNVGPSVSKYPLRNLQPASE--YTVSLVAIKGNQESPKATGVFTT----LQPGSSIPPY 1094
               + P ++ Y +  L+  ++  Y VS     G  +  +  G  T     ++P   +  +
Sbjct: 7037 NMKLVPELT-YKVTGLEKGNKYLYRVSAENKAGVSDPSEILGPLTADDAFVEPTMDLSAF 7095

Query: 1095 NTEV-----TETTIVI--TWTPAPRIGFKLGVRPSQGGEAPREVT-SDSGSIVVSGLTPG 1146
               +        TI++  T  P P   +  G +  + G+  +  T S    +V+S     
Sbjct: 7096 KDGLEVIVPNPITILVPSTGYPRPTATWCFGDKVLETGDRVKMKTLSAYAELVISPSERS 7155

Query: 1147 VEYVYTIQVLRDGQERDAPI-VNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPD--- 1202
             + +YT+++    +     I VN +  P +P      +   D+  LT  WE    PD   
Sbjct: 7156 DKGIYTLKLENRVKTISGEIDVNVIARPSAPKELKFGDITKDSVHLT--WE---PPDDDG 7210

Query: 1203 ---ITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEY--NVSVYTVKDDKESV 1257
               +TGY +     + +    + + V       T  +L  G EY   V         E  
Sbjct: 7211 GSPLTGYVVEKREVSRKTWTKVMDFV--TDLEFTVPDLVQGKEYLFKVCARNKCGPGEPA 7268

Query: 1258 PISDTIIPAVP-----PPTDLRFTNIGPDTMRVTWAPPPS---IDLTNFLVRYSPVKNEE 1309
             + + +  + P     PP ++++ +   +++ +TW PP +     +  ++V   P  +++
Sbjct: 7269 YVDEPVNMSTPATVPDPPENVKWRDRTANSIFLTWDPPKNDGGSRIKGYIVERCPRGSDK 7328

Query: 1310 DVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDI 1369
             VA      ++  + +T L  G  Y   V ++  Q  S P R  ++        +D  + 
Sbjct: 7329 WVA-CGEPVAETKMEVTGLEEGKWYAYRVKALNRQGASKPSRPTEEI-----QAVDTQEA 7382

Query: 1370 TANSFTVHWIAPRATITGYRIRHHPEHFSGRP-------REDRVPHSRNSITLTNLTPGT 1422
                  V  +A      G +I   P   +G+P       + D +      IT+ N+    
Sbjct: 7383 PEIFLDVKLLAGLTVKAGTKI-ELPATVTGKPEPKITWTKADMILKQDKRITIENVP--K 7439

Query: 1423 EYVVSIVALNGREESPLLI------GQQSTVSDV--------PRDLEVVAATPTSLLISW 1468
            +  V+IV     +    +I      G+ + V +V        P   ++   T  S L++W
Sbjct: 7440 KSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNVLDKPGPPAAFDITDVTNESCLLTW 7499

Query: 1469 DAP----AVTVRYYRITYGETGG------NSPVQEFTVPGSKSTATISGLKPGVDYTITV 1518
            + P       +  Y +    T        +S V++     +K       L P  +Y   V
Sbjct: 7500 NPPRDDGGSKITNYVVERRATDSEVWHKLSSTVKDTNFKATK-------LIPNKEYIFRV 7552

Query: 1519 YAVTGRG-DSPASSKPISINYRTE-IDKPSQMQVTDVQDNSISVKWL----PSSSPVTGY 1572
             A    G   P  + PI+  Y+ +    P++++ +D+  +++++ W        SP+TGY
Sbjct: 7553 AAENMYGVGEPVQASPITAKYQFDPPGPPTRLEPSDITKDAVTLTWCEPDDDGGSPITGY 7612

Query: 1573 RVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQP-------LV 1625
             V     +     +        T   ++GL    +Y   V A+N +G  +P       L+
Sbjct: 7613 WVERLDPDTDKWVRCNKMPVKDTTYRVKGLTNKKKYRFRVLAENLAGPGKPSKSTEPILI 7672

Query: 1626 QTAVTNIDRPKGLAFTDVDVDSIKIAWESPQ--GQVSRYRVTYSSPEDGIHELFPAPDGE 1683
            +  +     P      DV   S+++ W  P+  G            + G  E     +G 
Sbjct: 7673 KDPIDPPWPPGKPTVKDVGKTSVRLNWTKPEHDGGAKIESYVIEMLKTGTDEWVRVAEGV 7732

Query: 1684 EDTAE-LQGLRPGSEYTVSVVALHDDMESQ------PLIGTQSTAIPAPTD-LKFTQVTP 1735
              T   L GL  G EY+  V A++   ES+      P++  +    P+P   L+   +T 
Sbjct: 7733 PTTQHLLPGLMEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLEVINITK 7792

Query: 1736 TSLSAQWTPPNVQ----LTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVS 1791
             +   +WT P       +T Y V      + G  + ++     +   V+ L      E S
Sbjct: 7793 NTADLKWTVPEKDGGSPITNYIVEKRDVRRKG-WQTVDTTVKDTKCTVTPLT-----EGS 7846

Query: 1792 VYALKDTLTSRPAQGVVTTLEN----------VSPPRRARVTDATETTITISWRTKT--- 1838
            +Y  +    +   Q   T +E+            PP    V D T+  + + W       
Sbjct: 7847 LYVFRVAAENAIGQSDYTEIEDSVLAKDTFTTPGPPYALAVVDVTKRHVDLKWEPPKNDG 7906

Query: 1839 -ETITGFQVDAVPANGQTPIQ--RTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSP- 1894
               I  + ++     G   ++  +T  PD  ++ +T +  GT+ +  +   N+     P 
Sbjct: 7907 GRPIQRYVIEKKERLGTRWVKAGKTAGPDC-NFRVTDVIEGTEVQFQVRAENEAGVGHPS 7965

Query: 1895 ------VVIDASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPP 1944
                   + D ++    P +L         + ++W+PP     + I GY ++    G+  
Sbjct: 7966 EPTEILSIEDPTSPPSPPLDLHVTDAGRKHIAIAWKPPEKNGGSPIIGYHVEMCPVGTEK 8025

Query: 1945 -REVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQKTP 1996
               V  RP   +      G+ P  EY + V A+     SEP    +  V K P
Sbjct: 8026 WMRVNSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAIGVSEPSEISENVVAKDP 8078



 Score =  107 bits (266), Expect = 2e-22
 Identities = 292/1356 (21%), Positives = 513/1356 (37%), Gaps = 189/1356 (13%)

Query: 727   SVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQ--YLDLPSTA--TSVNIPDLLP 782
             +VTE+T+   V+SW    D   G ++++ + ++ +  +  + ++ S    T + +  LL 
Sbjct: 15258 AVTEVTSEKCVLSWFPPLDD-GGAKIDHYIVQKRETSRLAWTNVASEVQVTKLKVTKLLK 15316

Query: 783   GRKYI-----VNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAP 837
             G +YI     VN Y + E  E   +L+ +    PD P +P V  +   S+VV W  P + 
Sbjct: 15317 GNEYIFRVMAVNKYGVGEPLESEPVLAVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDS- 15375

Query: 838   ITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQ-------PGVQYNITIYAVEENQEST 890
               G   + +  VE            N  TL+DL+        G +Y   I A      S 
Sbjct: 15376 -DGGSEIINYIVERRDKAGQRWIKCNKKTLTDLRYKVSGLTEGHEYEFRIMAENAAGISA 15434

Query: 891   PVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNL 946
             P                  P + + ++ +   ++I W  P     S +TGY V++    L
Sbjct: 15435 PSPTSPFYKACDTVFKPGPPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIA---L 15491

Query: 947   PGEHGQRLPIS----RNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLD---A 999
             P E   ++       + T   +TGL+    Y  +++A++     +P     T K +    
Sbjct: 15492 PEEDEWQIVTPPAGLKATSYTITGLTENQEYKIRIYAMNSEGLGEPALVPGTPKAEDRML 15551

Query: 1000  PTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPR---QYNVGPSVSKYPLRNL 1056
             P  ++   +    V +R           RL V +  R  P      + G S+ K    ++
Sbjct: 15552 PPEIELDADLRKVVTIR------ACCTLRLFVPIKGRPAPEVKWARDHGESLDK---ASI 15602

Query: 1057  QPASEYTVSLVAIKGNQESPK----------ATGVFTTLQ----PGSSIPPYNTEVTETT 1102
             +  S YT+ +V      +S K          +   F  ++    PG        EVT+T+
Sbjct: 15603 ESTSSYTLLIVGNVNRFDSGKYILTVENSSGSKSAFVNVRVLDTPGPPQDLKVKEVTKTS 15662

Query: 1103  IVITWTPAPRI--GFKLGVRPSQGGEAPREVTS------DSGSIVVSGLTPGVEYVYTIQ 1154
             + +TW P P +  G K+     +  E+ R+  S         S  V  L  G  Y +  +
Sbjct: 15663 VTLTWDP-PLLDGGSKIKNYIVEKRESTRKAYSTVATNCHKTSWKVDQLQEGCSYYF--R 15719

Query: 1155  VLRDGQ------ERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPD---ITG 1205
             VL + +         A  V     PL P     ++   ++  +++SWE+        I G
Sbjct: 15720 VLAENEYGIGLPAETAESVKASERPLPPGKITLMDVTRNS--VSLSWEKPEHDGGSRILG 15777

Query: 1206  YRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYT-----VKDDKE-SVPI 1259
             Y I    T G    +    V   +++ T   L  G EY+  V       + D ++ SVP+
Sbjct: 15778 Y-IVEMQTKGSDKWATCATVKVTEATIT--GLIQGEEYSFRVSAQNEKGISDPRQLSVPV 15834

Query: 1260  --SDTIIPAVPPPTDLRFTNIGPDTMRV----TWAPPPSIDLTNFLVRYSPVKNEEDVAE 1313
                D +IP         FT +  + ++V       P P++      V   P+K       
Sbjct: 15835 IAKDLVIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNV---PLK---QTTR 15888

Query: 1314  LSISPSDNAVVLTNLLPGTE----YVVSV-SSVYEQHESTPLRGRQKTGLDSPTG-IDFS 1367
             ++   ++N  +LT      E    YVV + +S  E  E+  +    K G   PTG +   
Sbjct: 15889 VNAESTENNSLLTIKDACREDVGHYVVKLTNSAGEAIETLNVIVLDKPG--PPTGPVKMD 15946

Query: 1368  DITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTE 1423
             ++TA+S T+ W  P+    ++I  Y +    +  +   +      +R +I    L  G E
Sbjct: 15947 EVTADSITLSWGPPKYDGGSSINNYIVEKR-DTSTTTWQIVSATVARTTIKACRLKTGCE 16005

Query: 1424  YVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPT-------SLLISWDAP----A 1472
             Y   I A N   +S  L   + TV+  P  +     TP        S+ + W+ P     
Sbjct: 16006 YQFRIAAENRYGKSTYL-NSEPTVAQYPFKVPGPPGTPVVTLSSRDSMEVQWNEPISDGG 16064

Query: 1473  VTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSK 1532
               V  Y +   E      V+    P  ++    +GL+ GV+Y   V A    G    S  
Sbjct: 16065 SRVIGYHLERKERNSILWVKLNKTPIPQTKFKTTGLEEGVEYEFRVSAENIVGIGKPSKV 16124

Query: 1533  PISINYRTEIDKPSQMQVTDVQDNSISVKW----LPSSSPVTGYRVTTTPKNGPGPTKTK 1588
                   R   D P + +   V  NS++++W        S +TGY V           K  
Sbjct: 16125 SECYVARDPCDPPGRPEAIIVTRNSVTLQWKKPTYDGGSKITGYIVEKKELPEGRWMKAS 16184

Query: 1589  TAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE-SQPLVQT-AVTNIDR--PKGLAFTDVD 1644
                   T   + GL     Y   V A+N +G  S+P   T A+T  D   P  ++     
Sbjct: 16185 FTNIIDTHFEVTGLVEDHRYEFRVIARNAAGVFSEPSESTGAITARDEVDPPRISMDPKY 16244

Query: 1645  VDSIKI-AWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVV 1703
              D+I + A ES +         Y  P   I  +     G+++ +    L   S    + +
Sbjct: 16245 KDTIVVHAGESFKVDAD----IYGKPIPTIQWI----KGDQELSNTARLEIKSTDFATSL 16296

Query: 1704  ALHDD---------MESQPLIGTQSTAI-------PAPTD--LKFTQVTPTSLSAQWTPP 1745
             ++ D          ++++ + G +S  +       P P +  +  + VT    +  W PP
Sbjct: 16297 SVKDAVRVDSGNYILKAKNVAGERSVTVNVKVLDRPGPPEGPVVISGVTAEKCTLAWKPP 16356

Query: 1746  NVQLTGYRV--RVTPKEKTGPM--KEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTS 1801
              +Q  G  +   +  + +T  +    ++    + S  V+ L+   +Y   + A+      
Sbjct: 16357 -LQDGGSDIINYIVERRETSRLVWTVVDANVQTLSCKVTKLLEGNEYTFRIMAVNKYGVG 16415

Query: 1802  RPAQGVVTTLEN--VSP--PRRARVTDATETTITISWRTKT----ETITGFQVDAVPANG 1853
              P +      +N  V P  P+   VT  T+ ++ + W          I G+ ++     G
Sbjct: 16416 EPLESEPVVAKNPFVVPDAPKAPEVTTVTKDSMIVVWERPASDGGSEILGYVLEKRDKEG 16475

Query: 1854  --QTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDA-STAID------ 1904
                T   + +  ++R   +TGL    DY+  +   N    S P    A   A D      
Sbjct: 16476 IRWTRCHKRLIGELR-LRVTGLIENHDYEFRVSAENAAGLSEPSPPSAYQKACDPIYKPG 16534

Query: 1905  APSNLRFLATTPNSLLVSWQPP----RARITGYIIK 1936
              P+N + +  T +S+ +SW  P       I GYI++
Sbjct: 16535 PPNNPKVIDITRSSVFLSWSKPIYDGGCEIQGYIVE 16570



 Score =  106 bits (265), Expect = 2e-22
 Identities = 287/1431 (20%), Positives = 492/1431 (34%), Gaps = 191/1431 (13%)

Query: 730  EITASSFVVSWVSASDT----VSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRK 785
            +IT  S  ++W    D     ++G+ VE          + +D   T     +PDL+ G++
Sbjct: 7193 DITKDSVHLTWEPPDDDGGSPLTGYVVEKREVSRKTWTKVMDFV-TDLEFTVPDLVQGKE 7251

Query: 786  YIVNVYQISE--DGEQSLILSTSQTTAPDAPPDP--TVDQVDDT--SIVVRWSRPQ---- 835
            Y+  V   ++   GE + +      + P   PDP   V   D T  SI + W  P+    
Sbjct: 7252 YLFKVCARNKCGPGEPAYVDEPVNMSTPATVPDPPENVKWRDRTANSIFLTWDPPKNDGG 7311

Query: 836  APITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQ 895
            + I GY +   P           P     + ++ L+ G  Y   + A+     S P    
Sbjct: 7312 SRIKGYIVERCPRGSDKWVACGEPVAETKMEVTGLEEGKWYAYRVKALNRQGASKPSRPT 7371

Query: 896  QETTGTPRSDTVPSPRDLQFVEVTDVKV-------TIMWTPPESAVTGYRVDVIPVNLPG 948
            +E       +      D++ +    VK          +   PE  +T  + D+I      
Sbjct: 7372 EEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKR 7431

Query: 949  EHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNE 1008
               + +P         +  S   TY  +   V  GR +  +      K   P      + 
Sbjct: 7432 ITIENVPKKSTVTIVDSKRSDTGTYIIEAVNVC-GRATAVVEVNVLDKPGPPAAFDITDV 7490

Query: 1009 TDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTV 1064
            T+ + L+ W PPR    ++IT Y +    T      + +     + +    L P  EY  
Sbjct: 7491 TNESCLLTWNPPRDDGGSKITNYVVERRATDSEVWHKLSSTVKDTNFKATKLIPNKEYIF 7550

Query: 1065 SLVA--IKGNQESPKATGVFTTLQPGSSIPPYNTE---VTETTIVITWTP------APRI 1113
             + A  + G  E  +A+ +    Q     PP   E   +T+  + +TW        +P  
Sbjct: 7551 RVAAENMYGVGEPVQASPITAKYQFDPPGPPTRLEPSDITKDAVTLTWCEPDDDGGSPIT 7610

Query: 1114 GF---KLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTI---QVLRDGQERDAPIV 1167
            G+   +L     +     +    D+ +  V GLT   +Y + +    +   G+   +   
Sbjct: 7611 GYWVERLDPDTDKWVRCNKMPVKDT-TYRVKGLTNKKKYRFRVLAENLAGPGKPSKSTEP 7669

Query: 1168 NKVVTPLSPPTNLHLEANPDTGVLTV--SWERSTTPDITGYRITTTPTNGQQGNSLEEVV 1225
              +  P+ PP         D G  +V  +W   T P+  G     +          +E V
Sbjct: 7670 ILIKDPIDPPWPPGKPTVKDVGKTSVRLNW---TKPEHDGGAKIESYVIEMLKTGTDEWV 7726

Query: 1226 HADQSSCTFDNLSPGL----EYNVSVYTVKDDKESVPI--SDTIIPAVP-----PPTDLR 1274
               +   T  +L PGL    EY+  V  V    ES P   SD ++         PP  L 
Sbjct: 7727 RVAEGVPTTQHLLPGLMEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLE 7786

Query: 1275 FTNIGPDTMRVTWAPPPS---IDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPG 1331
              NI  +T  + W  P       +TN++V    V+ +     +  +  D    +T L  G
Sbjct: 7787 VINITKNTADLKWTVPEKDGGSPITNYIVEKRDVRRK-GWQTVDTTVKDTKCTVTPLTEG 7845

Query: 1332 TEYVVSVS-------SVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPR-- 1382
            + YV  V+       S Y + E + L     T    P  +   D+T     + W  P+  
Sbjct: 7846 SLYVFRVAAENAIGQSDYTEIEDSVLAKDTFTTPGPPYALAVVDVTKRHVDLKWEPPKND 7905

Query: 1383 --ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN----GREE 1436
                I  Y I       +   +  +      +  +T++  GTE    + A N    G   
Sbjct: 7906 GGRPIQRYVIEKKERLGTRWVKAGKTAGPDCNFRVTDVIEGTEVQFQVRAENEAGVGHPS 7965

Query: 1437 SP---LLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQE 1493
             P   L I   ++    P DL V  A    + I+W  P            E  G SP+  
Sbjct: 7966 EPTEILSIEDPTSPPSPPLDLHVTDAGRKHIAIAWKPP------------EKNGGSPIIG 8013

Query: 1494 FTVP----GSKSTATIS-------------GLKPGVDYTITVYAVTGRGDSPASSKPISI 1536
            + V     G++    ++             G+ P  +Y + V AV   G     S+P  I
Sbjct: 8014 YHVEMCPVGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAIG----VSEPSEI 8069

Query: 1537 NYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTE 1596
            +       P      D++ + I V      S    +R    P         +    D+  
Sbjct: 8070 SENVVAKDPDCKPTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLT 8129

Query: 1597 MTIEGLQPTVEYVVSVYA---------QNPSGESQPLVQTAVTNIDRP-KGLAFTDVDVD 1646
            M  + +   +E   SV A         +N  G +   +   V  +  P K +  +D+   
Sbjct: 8130 MKNDHISAHLEVPKSVRADAGIYTITLENKLGSATASINVKVIGLPGPCKDIKASDITKS 8189

Query: 1647 SIKIAWESPQ--GQVSRYRVTYSSPEDGIHELFPAPDGEEDTA-ELQGLRPGSEYTVSVV 1703
            S K+ WE P+  G            E G     P   GE   +  ++ L P  EY   V 
Sbjct: 8190 SCKLTWEPPEFDGGTPILHYVLERREAGRRTYIPVMSGENKLSWTVKDLIPNGEYFFRVK 8249

Query: 1704 ALH-----DDME-SQPLIGTQSTAIP-APTDLKFTQVTPTSLSAQWTPP----NVQLTGY 1752
            A++     + +E   P+I       P  P D++    T  +++  W PP      ++ GY
Sbjct: 8250 AVNKVGGGEYIELKNPVIAQDPKQPPDPPVDVEVHNPTAEAMTITWKPPLYDGGSKIMGY 8309

Query: 1753 RV-RVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTL 1811
             + ++   E+       +L P   +    GL    +Y+  V A      S P++    T 
Sbjct: 8310 IIEKIAKGEERWKRCNEHLVP-ILTYTAKGLEEGKEYQFRVRAENAAGISEPSRATPPT- 8367

Query: 1812 ENVSPPRRARVTDATETTI------------------TISWRTKTETITGFQVD------ 1847
            + V P    +V   T   +                  TI+W      I   ++       
Sbjct: 8368 KAVDPIDAPKVILRTSLEVKRGDEIALDASISGSPYPTITWIKDENVIVPEEIKKRAAPL 8427

Query: 1848 --------------AVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTL-NDNA-R 1891
                           +P   +  I  + K + +      L+P  D+ +Y+  + ND+   
Sbjct: 8428 VRRRKGEVQEEEPFVLPLTQRLSIDNSKKGESQLRVRDSLRP--DHGLYMIKVENDHGIA 8485

Query: 1892 SSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPP----RARITGYIIKYEKPGSPPRE- 1946
             +P  +        P N  F      S+L  W+PP     + I  Y ++ +    P  E 
Sbjct: 8486 KAPCTVSVLDTPGPPINFVFEDIRKTSVLCKWEPPLDDGGSEIINYTLEKKDKTKPDSEW 8545

Query: 1947 VVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQKTPF 1997
            +V        + ++T L  G EY ++ +  +N     P    K  V K PF
Sbjct: 8546 IVVTSTLRHCKYSVTKLIEGKEY-LFRVRAENRFGPGPPCVSKPLVAKDPF 8595



 Score =  106 bits (264), Expect = 3e-22
 Identities = 321/1571 (20%), Positives = 563/1571 (35%), Gaps = 259/1571 (16%)

Query: 590   YGRGIGEWHCQPLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQP---SHISKYILRWR 646
             YG G+     +P++       P  V + +     N+  I+W  P+    S I+ Y++  +
Sbjct: 18973 YGIGLPAETTEPVKVSEPPLPPGRVTLVDVTR--NTATIKWEKPESDGGSKITGYVVEMQ 19030

Query: 647   PKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPV 706
              K S  +W   T    L + TI GL  G  Y  ++ ++ + G  +  +          PV
Sbjct: 19031 TKGSE-KWSTCTQVKTLEA-TISGLTAGEEYVFRVAAVNEKGRSDPRQL-------GVPV 19081

Query: 707   TSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYL 766
              +  +  E  P   L   + +V         V +         +R + +  +E      +
Sbjct: 19082 IARDI--EIKPSVELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVN-V 19138

Query: 767   DLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDP---TVDQVD 823
                 T TS++I +     K  V  Y++        I         D P  P    +D+V 
Sbjct: 19139 SSSKTVTSLSIKE---ASKEDVGTYELCVSNSAGSITVPITIIVLDRPGPPGPIRIDEVS 19195

Query: 824   DTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNIT 879
               SI + W+ P+      I+ Y +    +   +   ++      S+ +  L  G +Y   
Sbjct: 19196 CDSITISWNPPEYDGGCQISNYIVEKKETTSTTWHIVSQAVARTSIKIVRLTTGSEYQFR 19255

Query: 880   I-----YAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE--- 931
             +     Y      ES+ VV +      P S   P P   + V  T   + + W  P    
Sbjct: 19256 VCAENRYGKSSYSESSAVVAEY-----PFSPPGP-PGTPKVVHATKSTMLVTWQVPVNDG 19309

Query: 932   -SAVTGYRVDVIP-VNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFA---VSHGRES 986
              S V GY ++     ++      ++ I+ +T  +V+GL  G+ Y ++V+A      G+ S
Sbjct: 19310 GSRVIGYHLEYKERSSILWSKANKILIA-DTQMKVSGLDEGLMYEYRVYAENIAGIGKCS 19368

Query: 987   K---PLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPR----AQITGY-----RLTVG-- 1032
             K   P+ A+     D P   +  N T  +V ++W+ P     A+ITGY      L  G  
Sbjct: 19369 KSCEPVPARDPC--DPPGQPEVTNITRKSVSLKWSKPHYDGGAKITGYIVERRELPDGRW 19426

Query: 1033  --------------LTRRGQPRQY-------NVGPSVSKYPLRNLQPASEYTVSLVAIKG 1071
                           +T   + ++Y       N   SVS+         SE T  ++ +K 
Sbjct: 19427 LKCNYTNIQETYFEVTELTEDQRYEFRVFARNAADSVSE--------PSESTGPII-VKD 19477

Query: 1072  NQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGF-KLGVRPSQGGEAPRE 1130
             + E P+   V   ++    I     EV +    I   P P I + K G+   +       
Sbjct: 19478 DVEPPR---VMMDVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEII 19534

Query: 1131  VTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGV 1190
              T +   + V          Y + +      R   +  KV+    PP    LE N  T  
Sbjct: 19535 STDNHTLLTVKDCIRRDTGQYVLTLKNVAGTRSVAVNCKVLDKPGPPAG-PLEINGLTAE 19593

Query: 1191  -LTVSWERSTTP---DITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEY--- 1243
               ++SW R       DI  Y +    T+       E  +    +SC    L  G EY   
Sbjct: 19594 KCSLSWGRPQEDGGADIDYYIVEKRETSHLAWTICEGELQ--MTSCKVTKLLKGNEYIFR 19651

Query: 1244  --NVSVYTVKDDKESVPISDTIIPAVP-PPTDLRFTNIGPDTMRVTWAPPPS---IDLTN 1297
                V+ Y V +  ESV I       VP PPT L  T++  ++M + W+ P S    +++ 
Sbjct: 19652 VTGVNKYGVGEPLESVAIKALDPFTVPSPPTSLEITSVTKESMTLCWSRPESDGGSEISG 19711

Query: 1298  FLVRYSPVKNEEDVAELSISP-SDNAVVLTNLLPGTEYVVSV-----SSVYEQHESTPL- 1350
             +++     KN      ++  P  D  V  T L  G EY   V     + +    E++PL 
Sbjct: 19712 YIIERRE-KNSLRWVRVNKKPVYDLRVKSTGLREGCEYEYRVYAENAAGLSLPSETSPLI 19770

Query: 1351  RGRQKTGLDS-PTGIDFSDITANSFTVHWIAP----RATITGYRIRHHPEHFSGRPREDR 1405
             R      L S P+     D    + T+ W+ P     A ITGY + +  +       +  
Sbjct: 19771 RAEDPVFLPSPPSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEY--KKSDDTDWKTS 19828

Query: 1406  VPHSRNS-ITLTNLTPGTEYVVSIVALN-----------------GREESPLLIGQQSTV 1447
             +   R +  T++ LT G EYV  + ++N                  REE PL        
Sbjct: 19829 IQSLRGTEYTISGLTTGAEYVFRVKSVNKVGASDPSDSSDPQIAKEREEEPLF----DID 19884

Query: 1448  SDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFT-VPGSKSTATI- 1505
             S++ + L V A    ++ + +    V      + + +   +   + +     S+++ TI 
Sbjct: 19885 SEMRKTLIVKAGASFTMTVPFRGRPVP----NVLWSKPDTDLRTRAYVDTTDSRTSLTIE 19940

Query: 1506  -SGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKW-L 1563
              +       YT+T+  V       A+S  + +        P+ + V DV   S  + W +
Sbjct: 19941 NANRNDSGKYTLTIQNVLS-----AASLTLVVKVLDTPGPPTNITVQDVTKESAVLSWDV 19995

Query: 1564  PSS---SPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE 1620
             P +   +PV  Y +     +        T   ++    +  LQ    Y   V  +N  G 
Sbjct: 19996 PENDGGAPVKNYHIEKREASKKAWVSV-TNNCNRLSYKVTNLQEGAIYYFRVSGENEFGV 20054

Query: 1621  SQPLVQTAVTNIDR----PKGLAFTDVDVDSIKIAWESPQGQVSRYRVTY--SSPEDGIH 1674
               P        I      P+ L  T +  DS+ + W  P+       V Y   + E G  
Sbjct: 20055 GIPAETKEGVKITEKPSPPEKLGVTSISKDSVSLTWLKPEHDGGSRIVHYVVEALEKGQK 20114

Query: 1675  ELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVT 1734
                     +     + GLR  SEY   V A     E+Q         +  P +L    + 
Sbjct: 20115 NWVKCAVAKSTHHVVSGLRENSEYFFRVFA-----ENQ-------AGLSDPREL----LL 20158

Query: 1735  PTSLSAQWTPPNVQL-----------TGYRVRVTPKEKTGPMKEINLAPD---------- 1773
             P  +  Q  PP + +            G  ++V       P+ ++ L+ D          
Sbjct: 20159 PVLIKEQLEPPEIDMKNFPSHTVYVRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRF 20218

Query: 1774  SSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGV------VTTLENVSPPR-RARVTDAT 1826
             ++ +    L +  K  V+  A +  +T+  + G       +  L+   PP     ++D T
Sbjct: 20219 NTEITAENLTINLKESVTADAGRYEITAANSSGTTKAFINIVVLDRPGPPTGPVVISDIT 20278

Query: 1827  ETTITISWR---------------TKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTIT 1871
             E ++T+ W                 K ET T     AV       + RT+        + 
Sbjct: 20279 EESVTLKWEPPKYDGGSQVTNYILLKRETST-----AVWTEVSATVARTM------MKVM 20327

Query: 1872  GLQPGTDYKIYL-----YTLNDNARSSPVVIDASTAIDAPSNLRFLA-TTPNSLLVSWQP 1925
              L  G +Y+  +     + ++D+  S+ V +        P +  ++   T  S+ V W  
Sbjct: 20328 KLTTGEEYQFRIKAENRFGISDHIDSACVTVKLPYTTPGPPSTPWVTNVTRESITVGWHE 20387

Query: 1926  P----RARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIAL----- 1976
             P     + + GY ++ +   S   +   +     T   +T +  G  Y   V A      
Sbjct: 20388 PVSNGGSAVVGYHLEMKDRNSILWQKANKLVIRTTHFKVTTISAGLIYEFRVYAENAAGV 20447

Query: 1977  -KNNQKSEPLI 1986
              K +  SEP++
Sbjct: 20448 GKPSHPSEPVL 20458



 Score =  105 bits (263), Expect = 4e-22
 Identities = 305/1451 (21%), Positives = 530/1451 (36%), Gaps = 208/1451 (14%)

Query: 688   GHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWV----SA 743
             G Q + R      S S PV    +     P  P+      VT +T+    ++W       
Sbjct: 17388 GGQYILRASNVAGSKSFPVNVKVLDRPGPPEGPV-----QVTGVTSEKCSLTWSPPLQDG 17442

Query: 744   SDTVSGFRVEYELSEEGDEPQYLDLPS--TATSVNIPDLLPGRKYI-----VNVYQISED 796
                +S + VE     E     +  + S     S+ +  LL G +Y+     VN Y + E 
Sbjct: 17443 GSDISHYVVE---KRETSRLAWTVVASEVVTNSLKVTKLLEGNEYVFRIMAVNKYGVGEP 17499

Query: 797   GEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ----APITGYRIVYSPSVEG- 851
              E + +L  +    P  P    V  +   S+ V W+RP     + I GY IV      G 
Sbjct: 17500 LESAPVLMKNPFVLPGPPKSLEVTNIAKDSMTVCWNRPDSDGGSEIIGY-IVEKRDRSGI 17558

Query: 852   ---SSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVP 908
                   +  + +    VT        ++ ++        E +P  +  +    P     P
Sbjct: 17559 RWIKCNKRRITDLRLRVTGLTEDHEYEFRVSAENAAGVGEPSPATVYYKAC-DPVFKPGP 17617

Query: 909   SPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPGEHGQRLPIS---RNTF 961
              P +   V+ T   +T+ W  P     S + GY V++   +   E  Q +      R T 
Sbjct: 17618 -PTNAHIVDTTKNSITLAWGKPIYDGGSEILGYVVEICKAD--EEEWQIVTPQTGLRVTR 17674

Query: 962   AEVTGLSPGVTYYFKVFAVSH----GRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRW 1017
              E++ L+    Y  +V A++        S P T +   KL+AP  L   +E    ++VR 
Sbjct: 17675 FEISKLTEHQEYKIRVCALNKVGLGEATSVPGTVKPEDKLEAP-ELDLDSELRKGIVVR- 17732

Query: 1018  TPPRAQITGYRLTVGLTRRGQPR----------------QYNVGPSVSKYPLRNL--QPA 1059
                     G    + +  +G+P                 Q   G + ++  + N     A
Sbjct: 17733 -------AGGSARIHIPFKGRPTPEITWSREEGEFTDKVQIEKGVNYTQLSIDNCDRNDA 17785

Query: 1060  SEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYN---TEVTETTIVITWTPAPRI--G 1114
              +Y + L    G++ +     V  T  PG   PP N    EV + +  + W P P I  G
Sbjct: 17786 GKYILKLENSSGSKSAFVTVKVLDT--PG---PPQNLAVKEVRKDSAFLVWEP-PIIDGG 17839

Query: 1115  FKLGVRPSQGGEAPREVTSD------SGSIVVSGLTPGVEYVYTIQVLRD---GQERDAP 1165
              K+        E+ R+  ++        S  V  LT G  Y + +    +   G   +  
Sbjct: 17840 AKVKNYVIDKRESTRKAYANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFGVGVPVETV 17899

Query: 1166  IVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPD---ITGYRITTTPTNGQQGNSLE 1222
                K   P SPP  + L     T   ++ WE+        + GY +   P   ++ + + 
Sbjct: 17900 DAVKAAEPPSPPGKVTLTDVSQTSA-SLMWEKPEHDGGSRVLGYVVEMQPKGTEKWSIVA 17958

Query: 1223  EVVHADQSSCTFDNLSPGLEY--NVSVYTVKDDKE----SVPI---SDTIIPAVPPPTDL 1273
             E   +   +     LS G EY   V  Y  K   +     VP+     TI P++  P + 
Sbjct: 17959 E---SKVCNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKLPFNT 18015

Query: 1274  RFTNIGPD---TMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLP 1330
                  G D    + V   P P+I   +++    P+K       +++  +  + VL ++  
Sbjct: 18016 YSIQAGEDLKIEIPVIGRPRPNI---SWVKDGEPLK---QTTRVNVEETATSTVL-HIKE 18068

Query: 1331  GTE------YVVSVSSVYEQHESTPLRGRQKTGLDSPTG-IDFSDITANSFTVHWIAPRA 1383
             G +       V + +S     E+  +   +K G   P G + F +++A+   + W  P  
Sbjct: 18069 GNKDDFGKYTVTATNSAGTATENLSVIVLEKPG--PPVGPVRFDEVSADFVVISWEPPAY 18126

Query: 1384  T----ITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPL 1439
             T    I+ Y +    +  +          +R +I +T L  GTEY   I A N   +S  
Sbjct: 18127 TGGCQISNYIVEKR-DTTTTTWHMVSATVARTTIKITKLKTGTEYQFRIFAENRYGKSAP 18185

Query: 1440  LIGQQSTVS------DVPRDLEVVAATPTSLLISWDAP----AVTVRYYRITYGETGGNS 1489
             L  +   V         P    V + +   +L+ W  P       +  Y +   E     
Sbjct: 18186 LDSKAVIVQYPFKEPGPPGTPFVTSISKDQMLVQWHEPVNDGGTKIIGYHLEQKEKNSIL 18245

Query: 1490  PVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQ 1549
              V+    P   +    +GL  G++Y   V A    G    S        R   D P + +
Sbjct: 18246 WVKLNKTPIQDTKFKTTGLDEGLEYEFKVSAENIVGIGKPSKVSECFVARDPCDPPGRPE 18305

Query: 1550  VTDVQDNSISVKW----LPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPT 1605
                +  N++++KW        S +TGY V           K       +TE T+ GL   
Sbjct: 18306 AIVITRNNVTLKWKKPAYDGGSKITGYIVEKKDLPDGRWMKASFTNVLETEFTVSGLVED 18365

Query: 1606  VEYVVSVYAQNPSGE-SQPLVQT-AVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYR 1663
               Y   V A+N +G  S+P   + A+T  D        ++D  +  +  +     V    
Sbjct: 18366 QRYEFRVIARNAAGNFSEPSDSSGAITARD--------EIDAPNASLDPKYKDVIVVHAG 18417

Query: 1664  VTYSSPED----GIHELFPAPDGE--EDTAELQGLRPGSEYTVSVV--ALHDD-----ME 1710
              T+    D     I ++  + DG+  E+TA    ++   + T  VV   +  D     ++
Sbjct: 18418 ETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQYILK 18477

Query: 1711  SQPLIGTQSTAI-------PAPTD--LKFTQVTPTSLSAQWTPPNVQLTGYRVR--VTPK 1759
                + GT+S  I       P P +  LK T VT       W PP +Q  G  +   +  K
Sbjct: 18478 LSNVGGTKSIPITVKVLDRPGPPEGPLKVTGVTAEKCYLAWNPP-LQDGGANISHYIIEK 18536

Query: 1760  EKTGPMK--EINLAPDSSSVVVSGLMVATKY-----EVSVYALKDTLTSRPAQGVVTTLE 1812
              +T  +   +++    + +  V+ L+   +Y      V+ Y + + L S P        +
Sbjct: 18537 RETSRLSWTQVSTEVQALNYKVTKLLPGNEYIFRVMAVNKYGIGEPLESGPVT-ACNPYK 18595

Query: 1813  NVSPPRRARVTDATETTITISWRTKTE----TITGFQVDAVPANG--QTPIQRTIKPDVR 1866
                PP    V+  T+ ++ ++W    +     I G+ ++     G   T   +    D+R
Sbjct: 18596 PPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDKEGVRWTKCNKKTLTDLR 18655

Query: 1867  SYTITGLQPGTDYKIYLYTLNDNARSSPV-------VIDASTAIDAPSNLRFLATTPNSL 1919
                +TGL  G  Y+  +   N      P          DA      PSN +   T+ +S+
Sbjct: 18656 -LRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRACDALYPPGPPSNPKVTDTSRSSV 18714

Query: 1920  LVSWQPP----RARITGYIIKYEKPGSPPREVVPRPRPGV--TEATITGLEPGTEYTIYV 1973
              ++W  P     A + GY+++  K  +        P  G+   + T+T L+  TEY   +
Sbjct: 18715 SLAWSKPIYDGGAPVKGYVVEV-KEAAADEWTTCTPPTGLQGKQFTVTKLKENTEYNFRI 18773

Query: 1974  IALKNNQKSEP 1984
              A+ +    EP
Sbjct: 18774 CAINSEGVGEP 18784



 Score =  103 bits (258), Expect = 2e-21
 Identities = 284/1417 (20%), Positives = 486/1417 (34%), Gaps = 169/1417 (11%)

Query: 606   PSSSGPVEVFITETPSQPNSHPIQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGH 662
             P   GPVE+    +        + W  P     S I  YIL  R  + +  W   +    
Sbjct: 14168 PGPPGPVEI----SNVSAEKATLTWTPPLEDGGSPIKSYILEKRETSRL-LWTVVSEDIQ 14222

Query: 663   LNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLV 722
                +    L  G  Y  ++ ++  YG  E             PV S  V        P  
Sbjct: 14223 SCRHVATKLIQGNEYIFRVSAVNHYGKGE-------------PVQSEPVKMVDRFGPPGP 14269

Query: 723   ATSESVTEITASSFVVSWVSASDT----VSGFRVEYELSEEGDEPQYLDLPSTATSVNIP 778
                  V+ +T ++  VSW    D     ++G+ VE    +     + +  P +     + 
Sbjct: 14270 PEKPEVSNVTKNTATVSWKRPVDDGGSEITGYHVERREKKSLRWVRAIKTPVSDLRCKVT 14329

Query: 779   DLLPGRKYIVNVYQISEDG------EQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWS 832
              L  G  Y   V   +  G          +L       P  P +P V      S  + W 
Sbjct: 14330 GLQEGSTYEFRVSAENRAGIGPPSEASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLAWG 14389

Query: 833   RPQ----APITGYRIVYSPSVEGSSTELNLPETANSVT---LSDLQPGVQYNITIYAVEE 885
             +P       ITGY +V    V   +   +   TA  +T   + DLQ   +YN  I A+ +
Sbjct: 14390 KPHYDGGLEITGY-VVEHQKVGDEAWIKDTTGTALRITQFVVPDLQTKEKYNFRISAIND 14448

Query: 886   NQESTPVVIQQ-ETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPV 944
                  P VI   E      +       +L+   V    ++I    P        V     
Sbjct: 14449 AGVGEPAVIPDVEIVEREMAPDFELDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKD 14508

Query: 945   NLPGEHGQRLPISRNTFAEVTGLSPGVTYYF--KVFAVSHGRESKPLTAQQTTKLDAP-- 1000
             N+  ++   +    NT +    + P    Y   K          K         LD P  
Sbjct: 14509 NINLKNRANI---ENTESFTLLIIPECNRYDTGKFVMTIENPAGKKSGFVNVRVLDTPGP 14565

Query: 1001  -TNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSK-----YPLR 1054
               NL+  + T  +V + W  P     G R+T  +  + +  + +   + +K     Y + 
Sbjct: 14566 VLNLRPTDITKDSVTLHWDLPLID-GGSRITNYIVEKREATRKSYSTATTKCHKCTYKVT 14624

Query: 1055  NLQPASEYTVSLVAIK--GNQESPKATGVFTTLQPGSSIPPYNT-EVTETTIVITWTPAP 1111
              L    EY   ++A    G  E  + T      +  S     N  ++T++T+ + W P P
Sbjct: 14625 GLSEGCEYFFRVMAENEYGIGEPTETTEPVKASEAPSPPDSLNIMDITKSTVSLAW-PKP 14683

Query: 1112  R-------IGFKLGVRPSQGGEAPREVTSDSG-SIVVSGLTPGVEYVYTIQVL----RDG 1159
             +        G+ +  +  +G +    +T+  G   VV  LT G EY + +  +    R  
Sbjct: 14684 KHDGGSKITGYVIEAQ-RKGSDQWTHITTVKGLECVVRNLTEGEEYTFQVMAVNSAGRSA 14742

Query: 1160  QERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWE--RSTTPDITGYRITTTPTNGQQ 1217
                  P++ K  T L     L L       V+  + +  +   P +   + T T   G Q
Sbjct: 14743 PRESRPVIVKEQTMLP---ELDLRGIYQKLVIAKAGDNIKVEIPVLGRPKPTVTWKKGDQ 14799

Query: 1218  G-NSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAV-----PPPT 1271
                  + V     ++ T  N++  +  +   Y +        + D I   V     PP  
Sbjct: 14800 ILKQTQRVNFETTATSTILNINECVRSDSGPYPLTARNIVGEVGDVITIQVHDIPGPPTG 14859

Query: 1272  DLRFTNIGPDTMRVTWAPPPS---IDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNL 1328
              ++F  +  D +  +W PP +   + ++N++V      +   V EL+ +        T L
Sbjct: 14860 PIKFDEVSSDFVTFSWDPPENDGGVPISNYVVEMRQTDSTTWV-ELATTVIRTTYKATRL 14918

Query: 1329  LPGTEYVVSVSS-----VYEQHESTPLRGRQKTGLDSPTGI-DFSDITANSFTVHWIAP- 1381
               G EY   V +     V     S  +       +  P G    + +T +S T+ W  P 
Sbjct: 14919 TTGLEYQFRVKAQNRYGVGPGITSACIVANYPFKVPGPPGTPQVTAVTKDSMTISWHEPL 14978

Query: 1382  ---RATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN------ 1432
                 + I GY +     +        +     N    + LT G  Y   ++A N      
Sbjct: 14979 SDGGSPILGYHVERKERNGILWQTVSKALVPGNIFKSSGLTDGIAYEFRVIAENMAGKSK 15038

Query: 1433  -GREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPV 1491
               +   P+L          P  L +   T T   + W  P  T  +   +Y     + P 
Sbjct: 15039 PSKPSEPMLALDPIDPPGKPVPLNITRHTVT---LKWAKPEYTGGFKITSYIVEKRDLPN 15095

Query: 1492  QEFTVPG----SKSTATISGLKPGVDYTITVYAVTGRGD-SPASSKPISINYRTEIDKPS 1546
               +         ++  T+SGL     Y   V A    G  SP S    +I  R +++ P 
Sbjct: 15096 GRWLKANFSNILENEFTVSGLTEDAAYEFRVIAKNAAGAISPPSEPSDAITCRDDVEAPK 15155

Query: 1547  QMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTK------TKTAGPDQTEMTIE 1600
                    +D  I             +R+       P PT        +  G  + E+ I 
Sbjct: 15156 IKVDVKFKDTVI-------LKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIA 15208

Query: 1601  GLQPTV---------EYVVSVYAQNPSGESQPLVQTAVTNIDRP----KGLAFTDVDVDS 1647
                  +             ++ A NP G ++ +    V  +DRP      LA T+V  + 
Sbjct: 15209 DFSTNLVNKDSTRRDSGAYTLTATNPGGFAKHIFNVKV--LDRPGPPEGPLAVTEVTSEK 15266

Query: 1648  IKIAWESP---QGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVA 1704
               ++W  P    G    + +        +     A + +    ++  L  G+EY   V+A
Sbjct: 15267 CVLSWFPPLDDGGAKIDHYIVQKRETSRLAWTNVASEVQVTKLKVTKLLKGNEYIFRVMA 15326

Query: 1705  LH-----DDMESQPLIGTQSTAIP-APTDLKFTQVTPTSLSAQWTPPN----VQLTGYRV 1754
             ++     + +ES+P++       P  P + + T +T  S+   W  P+     ++  Y V
Sbjct: 15327 VNKYGVGEPLESEPVLAVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEIINYIV 15386

Query: 1755  RVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYA-----LKDTLTSRPAQGVVT 1809
                 K     +K            VSGL    +YE  + A     +     + P      
Sbjct: 15387 ERRDKAGQRWIKCNKKTLTDLRYKVSGLTEGHEYEFRIMAENAAGISAPSPTSPFYKACD 15446

Query: 1810  TLENVSPPRRARVTDATETTITISWRTKT----ETITGFQVD-AVPANGQTPIQRTIKP- 1863
             T+    PP   RV D + ++I+I+W          ITG+ V+ A+P   +  I   + P 
Sbjct: 15447 TVFKPGPPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQI---VTPP 15503

Query: 1864  ---DVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVI 1897
                   SYTITGL    +YKI +Y +N      P ++
Sbjct: 15504 AGLKATSYTITGLTENQEYKIRIYAMNSEGLGEPALV 15540



 Score =  101 bits (252), Expect = 7e-21
 Identities = 270/1291 (20%), Positives = 463/1291 (35%), Gaps = 206/1291 (15%)

Query: 866   TLSDLQPGVQYNITIYAVEENQEST-PVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVT 924
             T++ L  G +Y   + A  EN+  T P    +      + D    P   +  +V+  ++T
Sbjct: 12051 TVTRLIEGNEYIFRVRA--ENKIGTGPPTESKPVIAKTKYDKPGRPDPPEVTKVSKEEMT 12108

Query: 925   IMWTPPE----SAVTGYRVDVIPVNLPGEHGQR-LPISRNTFAE----VTGLSPGVTYYF 975
             ++W PPE     ++TGY ++        +H  R +P++++   E    V  L P   Y F
Sbjct: 12109 VVWNPPEYDGGKSITGYFLEK-----KEKHSTRWVPVNKSAIPERRMKVQNLLPDHEYQF 12163

Query: 976   KVFAVSH------GRESKPLTAQQTTKLDAP-TNLQFVNETDSTVLVRWTPP----RAQI 1024
             +V A +          S+P+ A+   +   P TN + V+ T  ++ + W  P     A I
Sbjct: 12164 RVKAENEIGIGEPSLPSRPVVAKDPIEPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAPI 12223

Query: 1025  TGY------RLTVGLTRRGQPRQYNVGPSVSK-YPLRNLQPASEYTVSL-----VAIKGN 1072
              GY      ++       G  R       V K + + +L    EY   +     V I   
Sbjct: 12224 IGYVVEMRPKIADASPDEGWKRCNAAAQLVRKEFTVTSLDENQEYEFRVCAQNQVGIGRP 12283

Query: 1073  QESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWT-------------PAPRIGFKLGV 1119
              E  +A      L+P    P  + + +   +VI                PAP++ ++   
Sbjct: 12284 AELKEAIKPKEILEP----PEIDLDASMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVG 12339

Query: 1120  RPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTN 1179
               +   +   ++      +V+   T      Y++ ++    E+   +  +V+    P ++
Sbjct: 12340 IDNVVRKGQVDLVDTMAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFVNVRVLDTPGPVSD 12399

Query: 1180  LHLEANPDTGVLTVSW---ERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDN 1236
             L +     T    VSW   E      +T Y +     + +  +++   V   ++S    N
Sbjct: 12400 LKVSDVTKTSC-HVSWAPPENDGGSQVTHYIVEKREADRKTWSTVTPEVK--KTSFHVTN 12456

Query: 1237  LSPGLEYNVSVYTVKDDKESVP--ISDTIIPAVP-----PPTDLRFTNIGPDTMRVTWAP 1289
             L PG EY   V  V +    VP  +   ++ + P     PP  L  T +  ++  + W P
Sbjct: 12457 LVPGNEYYFRVTAVNEYGPGVPTDVPKPVLASDPLSEPDPPRKLEVTEMTKNSATLAWLP 12516

Query: 1290  P---PSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHE 1346
             P       +  ++  Y   +   D         D ++V+T L  G +Y   V++      
Sbjct: 12517 PLRDGGAKIDGYITSYREEEQPADRWTEYSVVKDLSLVVTGLKEGKKYKFRVAARNAVGV 12576

Query: 1347  STPLRGR----QKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPR 1402
             S P         K  L  P  +    IT  +             G ++R    H  G+P 
Sbjct: 12577 SLPREAEGVYEAKEQLLPPKILMPEQITIKA-------------GKKLRIEA-HVYGKPH 12622

Query: 1403  --------EDRV----------PHSRNSITLTNLTPGTEYVVSIVALNGR----EESPLL 1440
                     ED V            S + + + ++T       S+ A N      ++  ++
Sbjct: 12623 PTCKWKKGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVV 12682

Query: 1441  IGQQSTVSDVPRDLEVVAATPTSLLISWDAP----AVTVRYYRITYGETGGNSPVQEFTV 1496
             +         P D+  + A   SL  SW  P       +  Y +   +      V     
Sbjct: 12683 VMDAPGPPQPPFDISDIDADACSL--SWHIPLEDGGSNITNYIVEKCDVSRGDWVTALAS 12740

Query: 1497  PGSKSTATISGLKPGVDYTITVYAVTGRGDS-PASSKPISINYRTEI-DKPSQMQVTDVQ 1554
               +K++  +  L PG +Y   V A    G S P +S  +   +   +  +P   +VT V 
Sbjct: 12741 V-TKTSCRVGKLIPGQEYIFRVRAENRFGISEPLTSPKMVAQFPFGVPSEPKNARVTKVN 12799

Query: 1555  DNSISVKW-LPSS---SPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVV 1610
              + I V W  P S   SP+ GY +    +N     K        TE    GL   +EY  
Sbjct: 12800 KDCIFVAWDRPDSDGGSPIIGYLIERKERNSLLWVKANDTLVRSTEYPCAGLVEGLEYSF 12859

Query: 1611  SVYAQNPSGESQPLVQTAVTN----IDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTY 1666
              +YA N +G S P   T        +D P      DV   ++ + W  P+       + Y
Sbjct: 12860 RIYALNKAGSSPPSKPTEYVTARMPVDPPGKPEVIDVTKSTVSLIWARPKHDGGSKIIGY 12919

Query: 1667  -----SSPEDGIHELFPAPDG---EEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQ 1718
                    P D       AP     EE TA   GL   ++Y    +A      S P     
Sbjct: 12920 FVEACKLPGDKWVRCNTAPHQIPQEEYTAT--GLEEKAQYQFRAIARTAVNISPP----- 12972

Query: 1719  STAIPAPTDLKFTQVTPTSLSAQWTPPNVQLT-GYRVRVTPKEKTG----------PMKE 1767
                   P+D       P ++ A+  PP + L+   +  +T K  T           PM  
Sbjct: 12973 ----SEPSD-------PVTILAENVPPRIDLSVAMKSLLTVKAGTNVCLDATVFGKPMPT 13021

Query: 1768  INLAPDSSSVV-VSGLMVATKYEVSVYAL-----KD----TLTSRPAQGV------VTTL 1811
             ++   D + +    G+ +A +  +    L     KD    T+T+  + G       +  L
Sbjct: 13022 VSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTITAENSSGSKSATIKLKVL 13081

Query: 1812  ENVSPPRRARVTDATETTITISWRTKTET----ITGFQVDAVPANGQTPIQRTIKPDVRS 1867
             +   PP   ++         +SW    E     IT + VD    +     Q +    + S
Sbjct: 13082 DKPGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYIVDKRETSRPNWAQVSATVPITS 13141

Query: 1868  YTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTA---IDAPSNLR---FLATTPNSLLV 1921
              ++  L  G +Y+  +   N      PV  + + A    D P           T + + V
Sbjct: 13142 CSVEKLIEGHEYQFRICAENKYGVGDPVFTEPAIAKNPYDPPGRCDPPVISNITKDHMTV 13201

Query: 1922  SWQPPR----ARITGYIIKYEKPGSPPREVVPRPRPGVTEATI--TGLEPGTEYTIYVIA 1975
             SW+PP     + ITGY++  EK  +         R  + E T+  TGL+ GTEY   V A
Sbjct: 13202 SWKPPADDGGSPITGYLL--EKRETQAVNWTKVNRKPIIERTLKATGLQEGTEYEFRVTA 13259

Query: 1976  LKNNQKSEPLIGRKKTVQKTPFVTHPGYDTG 2006
             +    K+ P  G+     K  +   P Y  G
Sbjct: 13260 I---NKAGP--GKPSDASKAAYARDPQYPPG 13285



 Score =  101 bits (252), Expect = 7e-21
 Identities = 308/1501 (20%), Positives = 533/1501 (35%), Gaps = 204/1501 (13%)

Query: 624   NSHPIQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNS--YTIKGLKPGVVYE 678
             NS  + W  P+    S I +YIL  R K S  RW +      ++   + + GL  G  YE
Sbjct: 21861 NSITLTWARPESDGGSEIQQYILERREKKST-RWVKVISKRPISETRFKVTGLTEGNEYE 21919

Query: 679   GQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVV 738
               +++    G    +           PV          P  P V     VT+ + ++  +
Sbjct: 21920 FHVMAENAAGVGPASGIS-RLIKCREPVNP--------PGPPTVV---KVTDTSKTTVSL 21967

Query: 739   SW----VSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQIS 794
              W          + G+ +E   ++ GD  +        T   + DL  G +Y   V  I+
Sbjct: 21968 EWSKPVFDGGMEIIGYIIEMCKADLGDWHKVNAEACVKTRYTVTDLQAGEEYKFRVSAIN 22027

Query: 795   EDGEQSLILSTSQTTAPD--APPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGS 852
               G+      T    A D    P+  +D     + VVR          Y+   +P+   S
Sbjct: 22028 GAGKGDSCEVTGTIKAVDRLTAPELDIDANFKQTHVVRAGASIRLFIAYQGRPTPTAVWS 22087

Query: 853   STELNLPETANSVTLSDLQPGVQYNIT-------IYAVEENQESTPVVIQQETTGTPRSD 905
               + NL   A+  T          N            VE N  S  +    +   TP   
Sbjct: 22088 KPDSNLSLRADIHTTDSFSTLTVENCNRNDAGKYTLTVENNSGSKSITFTVKVLDTPGP- 22146

Query: 906   TVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPGEHGQRLPISRNTF 961
                 P  + F +VT    T+MW  P     + +  Y V+    +           +R  F
Sbjct: 22147 ----PGPITFKDVTRGSATLMWDAPLLDGGARIHHYVVEKREASRRSWQVISEKCTRQIF 22202

Query: 962   AEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQ----TTKLDAPTNLQFVNETDSTVLVRW 1017
              +V  L+ GV YYF+V AV+     +P    +    T +   P  L  V+ + S+ ++ W
Sbjct: 22203 -KVNDLAEGVPYYFRVSAVNEYGVGEPYEMPEPIVATEQPAPPRRLDVVDTSKSSAVLAW 22261

Query: 1018  TPP----RAQITGYRLTVGLTRRGQPRQYNVGPSVS-KYPLRNLQPASEY---------- 1062
               P     ++ITGY L   + ++G       G +    + +  L   +EY          
Sbjct: 22262 LKPDHDGGSRITGYLLE--MRQKGSDFWVEAGHTKQLTFTVERLVEKTEYEFRVKAKNDA 22319

Query: 1063  -------TVSLVAIKGNQESPKA--TGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRI 1113
                      S V IK  Q  P A  TG+   L    +  P+  +V      I+  PAP++
Sbjct: 22320 GYSEPREAFSSVIIKEPQIEPTADLTGITNQLITCKAGSPFTIDVP-----ISGRPAPKV 22374

Query: 1114  GFKL-GVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVT 1172
              +KL  +R  +        T D  ++ V     G    Y + +      +   +   V+ 
Sbjct: 22375 TWKLEEMRLKETDRVSITTTKDRTTLTVKDSMRGDSGRYFLTLENTAGVKTFSVTVVVIG 22434

Query: 1173  PLSPPTNLHLEANPDTGVLTVSW---ERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQ 1229
                P T     ++       +SW   +     +IT Y +    +       +   V   Q
Sbjct: 22435 RPGPVTGPIEVSSVSAESCVLSWGEPKDGGGTEITNYIVEKRESGTTAWQLVNSSVKRTQ 22494

Query: 1230  SSCTFDNLSPGLEYNVSV-----YTVKDDKESVPISDTIIPAVPP--PTDLRFTNIGPDT 1282
                T  +L+  +EY+  V     + V    ES PI     P VPP  PT     ++  + 
Sbjct: 22495 IKVT--HLTKYMEYSFRVSSENRFGVSKPLESAPII-AEHPFVPPSAPTRPEVYHVSANA 22551

Query: 1283  MRVTWAPPPSIDLTNFLVRYSPVKNEED----VAELSISPSDNAVVLTNLLPGTE----- 1333
             M + W  P   D  + ++ Y   K E +    V E  +   +    +T L+ G E     
Sbjct: 22552 MSIRWEEPYH-DGGSKIIGYWVEKKERNTILWVKENKVPCLECNYKVTGLVEGLEYQFRT 22610

Query: 1334  YVVSVSSVYEQHE-STPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPR----ATITGY 1388
             Y ++ + V +  E S P+  +    +D+P   + +D+T ++ ++ W AP     + + GY
Sbjct: 22611 YALNAAGVSKASEASRPIMAQNP--VDAPGRPEVTDVTRSTVSLIWSAPAYDGGSKVVGY 22668

Query: 1389  RIRHHPEHFSGRPREDRVPH---SRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQS 1445
              I   P    G  R  +  +   S N  T+T L+ G  Y   ++A N      +  G +S
Sbjct: 22669 IIERKPVSEVGDGRWLKCNYTIVSDNFFTVTALSEGDTYEFRVLAKNA--AGVISKGSES 22726

Query: 1446  TVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATI 1505
             T     RD            +  D   +      +     GG    +     G K     
Sbjct: 22727 TGPVTCRDEYAPPKAELDARLHGDLVTIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLC 22786

Query: 1506  SGLKPGVDYT----ITVYAVTGRGDS---------PASSKPISINYRTEIDKP---SQMQ 1549
                K  + YT      V     R DS          + +K +S+  +  +D P    ++ 
Sbjct: 22787 E--KVSLQYTGKRATAVIKFCDRSDSGKYTLTVKNASGTKAVSVMVKV-LDSPGPCGKLT 22843

Query: 1550  VTDVQDNSISVKW-LP---SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPT 1605
             V+ V     ++ W LP     + +T Y V           + +T+  +   + +EG  PT
Sbjct: 22844 VSRVTQEKCTLAWSLPQEDGGAEITHYIV----------ERRETSRLNW--VIVEGECPT 22891

Query: 1606  VEYVVS-----------VYAQNPSG-----ESQPLVQTAVTNIDRPKGL-AFTDVDVDSI 1648
             + YVV+           V A N  G     ES+P+V      I  P G+        + I
Sbjct: 22892 LSYVVTRLIKNNEYIFRVRAVNKYGPGVPVESEPIVARNSFTIPSPPGIPEEVGTGKEHI 22951

Query: 1649  KIAWESPQ----GQVSRYRVTYSSPED----GIHELFPAPDGEEDTAELQGLRPGSEYTV 1700
              I W  P+     ++S Y V     +      +++ +   D      ++  L  G +Y  
Sbjct: 22952 IIQWTKPESDGGNEISNYLVDKREKKSLRWTRVNKDYVVYD---TRLKVTSLMEGCDYQF 23008

Query: 1701  SVVALHDDMESQP------LIGTQSTAIPAPTDL-KFTQVTPTSLSAQWTPP----NVQL 1749
              V A++    S+P      +   + +  P P    +    T  S+S  WT P       +
Sbjct: 23009 RVTAVNAAGNSEPSEASNFISCREPSYTPGPPSAPRVVDTTKHSISLAWTKPMYDGGTDI 23068

Query: 1750  TGYRVRVTPKEKTGPMK-EINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGV- 1807
              GY + +  K+     +   N    ++   V  L +  KY   V A+     S  ++ + 
Sbjct: 23069 VGYVLEMQEKDTDQWYRVHTNATIRNTEFTVPDLKMGQKYSFRVAAVNVKGMSEYSESIA 23128

Query: 1808  -VTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPA-----NGQTPIQRTI 1861
              +  +E +  P    + D  + T+TI        +        P       G     R I
Sbjct: 23129 EIEPVERIEIP-DLELADDLKKTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAI 23187

Query: 1862  KPDVRSYTITGLQPGTDYKIYLYTL---NDNARSSPVVIDASTAIDAP-SNLRFLATTPN 1917
                  SY++  +     Y    YT+   N + + S  V+        P  +++    + +
Sbjct: 23188 IDTTESYSLLIVDKVNRYDAGKYTIEAENQSGKKSATVLVKVYDTPGPCPSVKVKEVSRD 23247

Query: 1918  SLLVSWQPPR----ARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYV 1973
             S+ ++W+ P     A +  YI++  +      + V   +   T   I+GL  GT Y   V
Sbjct: 23248 SVTITWEIPTIDGGAPVNNYIVEKREAAMRAFKTV-TTKCSKTLYRISGLVEGTMYYFRV 23306

Query: 1974  I 1974
             +
Sbjct: 23307 L 23307



 Score =  101 bits (252), Expect = 7e-21
 Identities = 364/1780 (20%), Positives = 631/1780 (35%), Gaps = 317/1780 (17%)

Query: 624   NSHPIQWNAPQPSHISKYILRW---RPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQ 680
             N+  I+W  P     SK I  W   + +N++   KE  +P    +Y + GL  G+ Y+ +
Sbjct: 22550 NAMSIRWEEPYHDGGSKIIGYWVEKKERNTILWVKENKVPCLECNYKVTGLVEGLEYQFR 22609

Query: 681   LISIQQYGHQEVTRFDFTTTSTSTPVTS-NTVTGETTPFSPLVATSESVTEITASSFVVS 739
               ++   G  + +         S P+ + N V     P          VT++T S+  + 
Sbjct: 22610 TYALNAAGVSKASE-------ASRPIMAQNPVDAPGRP---------EVTDVTRSTVSLI 22653

Query: 740   WVSAS----DTVSGFRVEYELSEEGDEPQYLDLPSTATSVN---IPDLLPGRKYIVNVYQ 792
             W + +      V G+ +E +   E  + ++L    T  S N   +  L  G  Y   V  
Sbjct: 22654 WSAPAYDGGSKVVGYIIERKPVSEVGDGRWLKCNYTIVSDNFFTVTALSEGDTYEFRVLA 22713

Query: 793   ISEDGEQSLILSTSQTTAPD------APPDPTVD-QVDDTSIVVRWSRPQAPITGYRIVY 845
              +  G   +I   S++T P       APP   +D ++    + +R         G  +V 
Sbjct: 22714 KNAAG---VISKGSESTGPVTCRDEYAPPKAELDARLHGDLVTIR--------AGSDLVL 22762

Query: 846   SPSVEGS----------STELNLPETANS----------VTLSDLQPGVQYNITIYAVEE 885
               +V G             EL+L E  +           +   D     +Y +T+     
Sbjct: 22763 DAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSGKYTLTVKNASG 22822

Query: 886   NQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDV 941
              +  + +V   ++ G     TV          VT  K T+ W+ P+    + +T Y V+ 
Sbjct: 22823 TKAVSVMVKVLDSPGPCGKLTVS--------RVTQEKCTLAWSLPQEDGGAEITHYIVE- 22873

Query: 942   IPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYY-----------FKVFAVS-HGR----E 985
                        R   SR  +  V G  P ++Y            F+V AV+ +G     E
Sbjct: 22874 -----------RRETSRLNWVIVEGECPTLSYVVTRLIKNNEYIFRVRAVNKYGPGVPVE 22922

Query: 986   SKPLTAQQTTKLDAPTNL-QFVNETDSTVLVRWTPPRA----QITGYRLTVGLTRRGQPR 1040
             S+P+ A+ +  + +P  + + V      ++++WT P +    +I+ Y   V    +   R
Sbjct: 22923 SEPIVARNSFTIPSPPGIPEEVGTGKEHIIIQWTKPESDGGNEISNY--LVDKREKKSLR 22980

Query: 1041  QYNVGPSVSKYPLR----NLQPASEYTVSLVAIK--GNQESPKATGVFTTLQPGSSI-PP 1093
                V      Y  R    +L    +Y   + A+   GN E  +A+   +  +P  +  PP
Sbjct: 22981 WTRVNKDYVVYDTRLKVTSLMEGCDYQFRVTAVNAAGNSEPSEASNFISCREPSYTPGPP 23040

Query: 1094  YNTEVTETT---IVITWTP------APRIGFKLGVRPSQGGEAPR---EVTSDSGSIVVS 1141
                 V +TT   I + WT          +G+ L ++     +  R     T  +    V 
Sbjct: 23041 SAPRVVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDTDQWYRVHTNATIRNTEFTVP 23100

Query: 1142  GLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPD---TGVLTVSWERS 1198
              L  G +Y + +  +      +       + P+       LE   D   T  +       
Sbjct: 23101 DLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEIPDLELADDLKKTVTIRAGASLR 23160

Query: 1199  TTPDITGYRITTTPTNGQQGNSLEEVVHADQS-SCTFDNLSPGLEYNVSVYTVKDDKESV 1257
                 ++G R     T  +QG  L      D + S +   +     Y+   YT++ + +S 
Sbjct: 23161 LMVSVSG-RPPPVITWSKQGIDLASRAIIDTTESYSLLIVDKVNRYDAGKYTIEAENQSG 23219

Query: 1258  PISDTIIPAV----PPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAE 1313
               S T++  V     P   ++   +  D++ +TW  P +ID    +  Y   K E  +  
Sbjct: 23220 KKSATVLVKVYDTPGPCPSVKVKEVSRDSVTITWEIP-TIDGGAPVNNYIVEKREAAMRA 23278

Query: 1314  ---LSISPSDNAVVLTNLLPGTEYVVSV--SSVY---EQHESTPLRGRQKTGLDSPTGID 1365
                ++   S     ++ L+ GT Y   V   ++Y   E  E++      +  L  P  ++
Sbjct: 23279 FKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYGIGEPCETSDAVLVSEVPL-VPAKLE 23337

Query: 1366  FSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRNSI---TLTNL 1418
               D+T ++ T+ W  P     + +TGY +       +G  R  +V   + ++   T+T+L
Sbjct: 23338 VVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACK---AGTERWMKVVTLKPTVLEHTVTSL 23394

Query: 1419  TPGTEYVVSIVALNGREESPLLIGQQSTVSDVP-RDLEVVAATPTSLLISWDAPAVTVRY 1477
               G +Y+  I A N +  S      + TV+ V  +DL V+     S +          R 
Sbjct: 23395 NEGEQYLFRIRAQNEKGVSE----PRETVTAVTVQDLRVLPTIDLSTMPQKTIHVPAGRP 23450

Query: 1478  YRITYGETGGNSPVQEFTVPGSKS-----------------TATISGLKPGVDYTITVYA 1520
               +     G   P   +   GSK                  T   + ++   +YT+ +  
Sbjct: 23451 VELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAKLTIRETTIRDTGEYTLELKN 23510

Query: 1521  VTGRGDSPASSKPISINYRTEIDKPSQ----MQVTDVQDNSISVKWLP----SSSPVTGY 1572
             VTG      +S+ I +     +DKP      +++ ++   SI++ W P      +P++GY
Sbjct: 23511 VTG-----TTSETIKVII---LDKPGPPTGPIKIDEIDATSITISWEPPELDGGAPLSGY 23562

Query: 1573  RVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPL------VQ 1626
              V     + PG      +    T      L    EYV  V A N  G    L       +
Sbjct: 23563 VVEQRDAHRPGWLPVSESVTRST-FKFTRLTEGNEYVFRVAATNRFGIGSYLQSEVIECR 23621

Query: 1627  TAVTNIDRPKGLAFTDVDVDSIKIAWESPQ----GQVSRYRVTYSSPEDGIHELFPAPDG 1682
             +++     P+ L   DV  D + + W  P+     QV+ Y V                  
Sbjct: 23622 SSIRIPGPPETLQIFDVSRDGMTLTWYPPEDDGGSQVTGYIVERKEVRADRWVRVNKVPV 23681

Query: 1683  EEDTAELQGLRPGSEYTVSVVALH------DDMESQPLIGTQSTAIPA-PTDLKFTQVTP 1735
                     GL  G EY   V A++          S+P++     A P  P + + T  T 
Sbjct: 23682 TMTRYRSTGLTEGLEYEHRVTAINARGSGKPSRPSKPIVAMDPIAPPGKPQNPRVTDTTR 23741

Query: 1736  TSLSAQWTPPNVQ----LTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVS 1791
             TS+S  W+ P  +    +TGY + +   ++    K            ++ L    +Y   
Sbjct: 23742 TSVSLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTKCNTTPTKIREYTLTHLPQGAEYRFR 23801

Query: 1792  VYALKDTLTSRPAQ--GVVTTLENVSPP---------RRARVTDATETTITISWRTKTET 1840
             V A        PA+  G V   E +  P             V       +TI  + K   
Sbjct: 23802 VLACNAGGPGEPAEVPGTVKVTEMLEYPDYELDERYQEGIFVRQGGVIRLTIPIKGKP-- 23859

Query: 1841  ITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGT--DYKIYLYTLNDNARSSPVVID 1898
                F +      GQ   +R +     ++T   ++     D   Y   L +      V I 
Sbjct: 23860 ---FPICKWTKEGQDISKRAMIATSETHTELVIKEADRGDSGTYDLVLENKCGKKAVYIK 23916

Query: 1899  ASTAIDAPSN----LRFLATTPNSLLVSWQPPR----ARITGYII-KYEKPGSPPREVVP 1949
                 I +P++    L +      S+ VSW+PP     A I GYI+ + E P +    +  
Sbjct: 23917 VRV-IGSPNSPEGPLEYDDIQVRSVRVSWRPPADDGGADILGYILERREVPKAAWYTIDS 23975

Query: 1950  RPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQKTPFVTHPGYDTGNGI 2009
             R R   T   + GL+   EY   V A      S+PL   +    KTP             
Sbjct: 23976 RVRG--TSLVVKGLKENVEYHFRVSAENQFGISKPLKSEEPVTPKTPL------------ 24021

Query: 2010  QLPGTSGQQPSVGQQMIFEEHGFRRTTPPTTATPIRHRPRPYPPNVGQEALSQTTISWAP 2069
                                        PP         P   PP V     S  ++SW+ 
Sbjct: 24022 --------------------------NPP--------EPPSNPPEVLDVTKSSVSLSWSR 24047

Query: 2070  FQD-----TSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKD--- 2121
              +D      + Y I      TD+     +   T+T  T+TGL   A Y   + A  D   
Sbjct: 24048 PKDDGGSRVTGYYIERKETSTDKWVRHNKTQITTTMYTVTGLVPDAEYQFRIIAQNDVGL 24107

Query: 2122  QQRHKVREEVVTVGNSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLG 2181
              +     E VV       +  ++P+     +  ++S  +V  +WE+    G K   + LG
Sbjct: 24108 SETSPASEPVV-----CKDPFDKPSQPGELEILSISKDSVTLQWEKPECDGGK---EILG 24159

Query: 2182  FGSGHFRCDSSRWCHDNGVNYKIGEKWDRQGENGQMMSCT 2221
             +   + +   S W   N    K     D+Q   G ++  T
Sbjct: 24160 YWVEYRQSGDSAWKKSNKERIK-----DKQFTIGGLLEAT 24194



 Score = 99.8 bits (247), Expect = 3e-20
 Identities = 305/1551 (19%), Positives = 537/1551 (34%), Gaps = 252/1551 (16%)

Query: 610   GPVEVFITETPSQPNSHPIQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSY 666
             GPV        ++ + H + W  P+    S ++ YI+  R  +    W   T      S+
Sbjct: 12395 GPVSDLKVSDVTKTSCH-VSWAPPENDGGSQVTHYIVEKREADRK-TWSTVTPEVKKTSF 12452

Query: 667   TIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSE 726
              +  L PG  Y  ++ ++ +YG           T    PV ++    E  P   L     
Sbjct: 12453 HVTNLVPGNEYYFRVTAVNEYG-------PGVPTDVPKPVLASDPLSEPDPPRKL----- 12500

Query: 727   SVTEITASSFVVSWV----SASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLP 782
              VTE+T +S  ++W+         + G+   Y   E+  +           S+ +  L  
Sbjct: 12501 EVTEMTKNSATLAWLPPLRDGGAKIDGYITSYREEEQPADRWTEYSVVKDLSLVVTGLKE 12560

Query: 783   GRKY-----IVNVYQISEDGEQSLILSTSQTTAPD---APPDPTVDQVDDTSIVVRWSRP 834
             G+KY       N   +S   E   +    +   P     P   T+       I       
Sbjct: 12561 GKKYKFRVAARNAVGVSLPREAEGVYEAKEQLLPPKILMPEQITIKAGKKLRIEAHVYGK 12620

Query: 835   QAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDL--QPGVQYNITIYAVEENQESTPV 892
               P   ++      V  S   ++  ++++ + + D+  +    Y++T             
Sbjct: 12621 PHPTCKWKKGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIK 12680

Query: 893   VIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPG 948
             V+  +  G P+      P D+  ++      ++ W  P     S +T Y V+   V+  G
Sbjct: 12681 VVVMDAPGPPQ-----PPFDISDIDAD--ACSLSWHIPLEDGGSNITNYIVEKCDVS-RG 12732

Query: 949   EHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKL------DAPTN 1002
             +    L     T   V  L PG  Y F+V A +    S+PLT+ +            P N
Sbjct: 12733 DWVTALASVTKTSCRVGKLIPGQEYIFRVRAENRFGISEPLTSPKMVAQFPFGVPSEPKN 12792

Query: 1003  LQFVNETDSTVLVRWTPPRAQ----ITGYRLTVGLTRRGQPRQYNVGPSV---SKYPLRN 1055
              +        + V W  P +     I GY   +    R          ++   ++YP   
Sbjct: 12793 ARVTKVNKDCIFVAWDRPDSDGGSPIIGY--LIERKERNSLLWVKANDTLVRSTEYPCAG 12850

Query: 1056  LQPASEYTVSLVAIKGNQESP--KATGVFTTLQPGSSIPPYNTE---VTETTIVITWT-P 1109
             L    EY+  + A+     SP  K T   T   P    PP   E   VT++T+ + W  P
Sbjct: 12851 LVEGLEYSFRIYALNKAGSSPPSKPTEYVTARMPVD--PPGKPEVIDVTKSTVSLIWARP 12908

Query: 1110  APRIGFKL-----------GVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVY------- 1151
                 G K+           G +  +   AP ++  +      +GL    +Y +       
Sbjct: 12909 KHDGGSKIIGYFVEACKLPGDKWVRCNTAPHQIPQE--EYTATGLEEKAQYQFRAIARTA 12966

Query: 1152  -------------TIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANP-DTGVLTVSWER 1197
                          TI         D  +  K +  +   TN+ L+A      + TVSW++
Sbjct: 12967 VNISPPSEPSDPVTILAENVPPRIDLSVAMKSLLTVKAGTNVCLDATVFGKPMPTVSWKK 13026

Query: 1198  STTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFD----NLSPGLEYNVSVYTVKDD 1253
               T           P  G +       +   ++ CT +    N     +Y ++       
Sbjct: 13027 DGT--------LLKPAEGIK-------MAMQRNLCTLELFSVNRKDSGDYTITAENSSGS 13071

Query: 1254  KESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPP---PSIDLTNFLVRYSPVKNEED 1310
             K S  I   ++    PP  ++   +  D   ++W PP      ++TN++V      +  +
Sbjct: 13072 K-SATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYIVDKRET-SRPN 13129

Query: 1311  VAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPL---RGRQKTGLDSPTGID-- 1365
              A++S +    +  +  L+ G EY   + +  +     P+       K   D P   D  
Sbjct: 13130 WAQVSATVPITSCSVEKLIEGHEYQFRICAENKYGVGDPVFTEPAIAKNPYDPPGRCDPP 13189

Query: 1366  -FSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTP 1420
               S+IT +  TV W  P     + ITGY +           + +R P    ++  T L  
Sbjct: 13190 VISNITKDHMTVSWKPPADDGGSPITGYLLEKRETQAVNWTKVNRKPIIERTLKATGLQE 13249

Query: 1421  GTEYVVSIVALNGREESPLLIGQQSTVSDV------------PRDLEVVAATPTSLLISW 1468
             GTEY   + A+N  +  P   G+ S  S              P   +V   T +S+ +SW
Sbjct: 13250 GTEYEFRVTAIN--KAGP---GKPSDASKAAYARDPQYPPGPPAFPKVYDTTRSSVSLSW 13304

Query: 1469  DAPAV----TVRYYRITYGETGGNSPVQEFTVPGS--KSTATISGLKPGVDYTITVYAVT 1522
               PA      +  Y +       ++ V+   +P +  K+   ++GL     Y   VYAV 
Sbjct: 13305 GKPAYDGGSPIIGYLVEVKRADSDNWVR-CNLPQNLQKTRFEVTGLMEDTQYQFRVYAVN 13363

Query: 1523  GRG-----DSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTT 1577
               G     D P    P  I    E +  + ++ T +    ++++      PV G      
Sbjct: 13364 KIGYSDPSDVPDKHYPKDILIPPEGELDADLRKTLILRAGVTMRLY---VPVKGRPPPKI 13420

Query: 1578  PKNGPGPTKTKTAGPD------QTEMTIEGLQ--PTVEYVVSVYAQNPSGESQPLVQTAV 1629
               + P        G D       T +  E +      +Y++++  +N  G+ +  +   V
Sbjct: 13421 TWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKYILTL--ENSCGKKEYTIVVKV 13478

Query: 1630  TNIDRPK-GLAFTDVDVDSIKIAWESP----QGQVSRYRVTYSSPEDGIHELFPAPDGEE 1684
              +   P   +   ++  DS  + WE P       +  Y V     E          +  +
Sbjct: 13479 LDTPGPPVNVTVKEISKDSAYVTWEPPIIDGGSPIINYVVQKRDAERKSWSTV-TTECSK 13537

Query: 1685  DTAELQGLRPGSEYTVSVVA-----LHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLS 1739
              +  +  L  G  Y   V A     + D  E++  +    T  P   DLK   V+ +S S
Sbjct: 13538 TSFRVANLEEGKSYFFRVFAENEYGIGDPGETRDAVKASQTPGPV-VDLKVRSVSKSSCS 13596

Query: 1740  AQWTPPN----VQLTGYRVRVTPKEKTGP--MKEINLAPDSSSVVVSGLMVATKYEVSVY 1793
               W  P+     ++ GY V    +E      MK ++L   +       L    +Y   V 
Sbjct: 13597 IGWKKPHSDGGSRIIGYVVDFLTEENKWQRVMKSLSLQYSAKD-----LTEGKEYTFRVS 13651

Query: 1794  ALKDTLTSRPAQGVVTTLENVSPPR-------------------RARVTDATETTITISW 1834
             A  +     P++  V   ++V  P                    R ++    +   ++SW
Sbjct: 13652 AENENGEGTPSEITVVARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPIKGKPAPSVSW 13711

Query: 1835  RTKTE---TITGFQVDAVPANGQTPIQRTIKPDVRSYTIT-----GLQPGTDYKIYLYTL 1886
             +   +   T T   V++   N    +    K D   YTIT     G + GT         
Sbjct: 13712 KKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKEGT--------- 13762

Query: 1887  NDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGS 1942
                   S  V+        P  ++F   T  ++ + W PP+    + IT YI++ ++   
Sbjct: 13763 -----ISIKVVGKPGIPTGP--IKFDEVTAEAMTLKWAPPKDDGGSEITNYILE-KRDSV 13814

Query: 1943  PPREVVPRPRPGVTEATITGLEPGTEYTIYVIA-----LKNNQKSEPLIGR 1988
               + V        T   +T L  G EYT  V A     +    KSEP++ R
Sbjct: 13815 NNKWVTCASAVQKTTFRVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVAR 13865



 Score = 96.7 bits (239), Expect = 2e-19
 Identities = 334/1533 (21%), Positives = 553/1533 (36%), Gaps = 218/1533 (14%)

Query: 619   TPSQPNSHPIQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGV 675
             T S  +S  +QWN P     S +  Y L  + +NS+   K    P     +   GL+ GV
Sbjct: 16045 TLSSRDSMEVQWNEPISDGGSRVIGYHLERKERNSILWVKLNKTPIPQTKFKTTGLEEGV 16104

Query: 676   VYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASS 735
              YE ++ +    G                P   +       P  P     E++  +T +S
Sbjct: 16105 EYEFRVSAENIVG-------------IGKPSKVSECYVARDPCDP-PGRPEAII-VTRNS 16149

Query: 736   FVVSW----VSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVY 791
               + W          ++G+ VE +   EG   +        T   +  L+   +Y   V 
Sbjct: 16150 VTLQWKKPTYDGGSKITGYIVEKKELPEGRWMKASFTNIIDTHFEVTGLVEDHRYEFRVI 16209

Query: 792   QISEDGEQSLIL-STSQTTAPDA--PPDPTVDQVDDTSIVVRWS---RPQAPITGYRIVY 845
               +  G  S    ST   TA D   PP  ++D     +IVV      +  A I G  I  
Sbjct: 16210 ARNAAGVFSEPSESTGAITARDEVDPPRISMDPKYKDTIVVHAGESFKVDADIYGKPI-- 16267

Query: 846   SPSVEGSSTELNLPETAN-SVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRS 904
              P+++    +  L  TA   +  +D    +     +       +S   +++ +     RS
Sbjct: 16268 -PTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRV-----DSGNYILKAKNVAGERS 16321

Query: 905   DTV-------PSPRDLQFV--EVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLP 955
              TV       P P +   V   VT  K T+ W PP   +     D+I   +      RL 
Sbjct: 16322 VTVNVKVLDRPGPPEGPVVISGVTAEKCTLAWKPP---LQDGGSDIINYIVERRETSRLV 16378

Query: 956   IS------RNTFAEVTGLSPGVTYYFKVFAVS-----HGRESKPLTAQQTTKL-DAPTNL 1003
              +      +    +VT L  G  Y F++ AV+        ES+P+ A+    + DAP   
Sbjct: 16379 WTVVDANVQTLSCKVTKLLEGNEYTFRIMAVNKYGVGEPLESEPVVAKNPFVVPDAPKAP 16438

Query: 1004  QFVNETDSTVLVRWTPPRA----QITGYRLTV----GLTRRGQPRQYNVGPSVSKYPLRN 1055
             +    T  +++V W  P +    +I GY L      G+ R  +  +  +G    +     
Sbjct: 16439 EVTTVTKDSMIVVWERPASDGGSEILGYVLEKRDKEGI-RWTRCHKRLIGELRLRVTGLI 16497

Query: 1056  LQPASEYTVSLVAIKGNQE-SPKAT---GVFTTLQPGSSIPPYNTEVTETTIVITWTPAP 1111
                  E+ VS     G  E SP +          +PG    P   ++T +++ ++W+   
Sbjct: 16498 ENHDYEFRVSAENAAGLSEPSPPSAYQKACDPIYKPGPPNNPKVIDITRSSVFLSWSKPI 16557

Query: 1112  RIGF---------KLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRD---G 1159
               G          K  V   +          +  +I V  L    EY + I  +     G
Sbjct: 16558 YDGGCEIQGYIVEKCDVSVGEWTMCTPPTGINKTNIEVEKLLEKHEYNFRICAINKAGVG 16617

Query: 1160  QERDAPIVNKVVTPL-SPPTNLHLEANPDTGV-------LTVSWERSTTPDITGYRITTT 1211
             +  D P    V   L +P  +L LE      +       L V  +   TP++   ++   
Sbjct: 16618 EHADVPGPIIVEEKLEAPDIDLDLELRKIINIRAGGSLRLFVPIKGRPTPEVKWGKV--- 16674

Query: 1212  PTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTV----KDDKESVPISDTIIPAV 1267
               +G+  ++    V +  +S   DN++    Y+   YT+        +S  ++  ++   
Sbjct: 16675 --DGEIRDAAIIDVTSSFTSLVLDNVN---RYDSGKYTLTLENSSGTKSAFVTVRVLDTP 16729

Query: 1268  PPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNE---EDVAELSISPSDNAVV 1324
              PP +L+ T I  D++ +TW  PP +D  + +  Y   K E   +  A +  +   N+  
Sbjct: 16730 SPPVNLKVTEITKDSVSITW-EPPLLDGGSKIKNYIVEKREATRKSYAAVVTNCHKNSWK 16788

Query: 1325  LTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGL----DSPTGIDFSDITANSFTVHWIA 1380
             +  L  G  Y   V++  E     P +      +      P  I   D+T NS ++ W  
Sbjct: 16789 IDQLQEGCSYYFRVTAENEYGIGLPAQTADPIKVAEVPQPPGKITVDDVTRNSVSLSWTK 16848

Query: 1381  PR----ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREE 1436
             P     + I  Y +    +H        RV   +    +TNLT G EY+  +VA+N +  
Sbjct: 16849 PEHDGGSKIIQYIVEMQAKHSEKWSECARVKSLQ--AVITNLTQGEEYLFRVVAVNEKGR 16906

Query: 1437  S-PLLIGQQSTVSDVPRDLEVVAA-TPTSLLISWD----APAVTVRYYRITYGETGGNSP 1490
             S P  +       D+  + +V  A +  S+ +  D     P        IT+ + G   P
Sbjct: 16907 SDPRSLAVPIVAKDLVIEPDVKPAFSSYSVQVGQDLKIEVPISGRPKPTITWTKDG--LP 16964

Query: 1491  VQEFT---VPGSKSTATIS----GLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEID 1543
             +++ T   V  S    T+S        G  Y ITV  V G+       K  SI   T +D
Sbjct: 16965 LKQTTRINVTDSLDLTTLSIKETHKDDGGQYGITVANVVGQ-------KTASIEIVT-LD 17016

Query: 1544  KP----SQMQVTDVQDNSISVKWLP----SSSPVTGYRV-----TTTPKNGPGPTKTKTA 1590
             KP      ++  DV   SI++ W P        +T Y V     TTT  +    T  +T 
Sbjct: 17017 KPDPPKGPVKFDDVSAESITLSWNPPLYTGGCQITNYIVQKRDTTTTVWDVVSATVARTT 17076

Query: 1591  GPDQTEMTIEGLQPTVEYVVSVYAQNPSG-----ESQPLVQTAVTNIDRPKGLAF-TDVD 1644
                   + +  L+   EY   ++A+N  G     ES P+V         P G  F T + 
Sbjct: 17077 ------LKVTKLKTGTEYQFRIFAENRYGQSFALESDPIVAQYPYKEPGPPGTPFATAIS 17130

Query: 1645  VDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGE---EDTA-ELQGLRPGSEYTV 1700
              DS+ I W  P        + Y       + +      +    DT  + Q L  G EY  
Sbjct: 17131 KDSMVIQWHEPVNNGGSPVIGYHLERKERNSILWTKVNKTIIHDTQFKAQNLEEGIEYEF 17190

Query: 1701  SVVALHDDMESQPLIGTQSTAIPAPTDLKFT----QVTPTSLSAQWTPP----NVQLTGY 1752
              V A +     +    ++      P D   T     V    ++ QWT P       +TGY
Sbjct: 17191 RVYAENIVGVGKASKNSECYVARDPCDPPGTPEPIMVKRNEITLQWTKPVYDGGSMITGY 17250

Query: 1753  RVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDT-LTSRPAQ--GVVT 1809
              V          MK        +   VSGL    +YE  V A       S+P+   G +T
Sbjct: 17251 IVEKRDLPDGRWMKASFTNVIETQFTVSGLTEDQRYEFRVIAKNAAGAISKPSDSTGPIT 17310

Query: 1810  TLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYT 1869
               + V  PR +      +T +  +  T       F+++A       P    ++ D     
Sbjct: 17311 AKDEVELPRISMDPKFRDTIVVNAGET-------FRLEADVHGKPLPTIEWLRGDKEIEE 17363

Query: 1870  ITGLQ-PGTDYKIYL------------YTLNDN----ARSSPV---VIDASTAIDAPSNL 1909
                 +   TD+K  L            Y L  +    ++S PV   V+D     + P  +
Sbjct: 17364 SARCEIKNTDFKALLIVKDAIRIDGGQYILRASNVAGSKSFPVNVKVLDRPGPPEGP--V 17421

Query: 1910  RFLATTPNSLLVSWQPP----RARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEP 1965
             +    T     ++W PP     + I+ Y+++ ++  S     V           +T L  
Sbjct: 17422 QVTGVTSEKCSLTWSPPLQDGGSDISHYVVE-KRETSRLAWTVVASEVVTNSLKVTKLLE 17480

Query: 1966  GTEYTIYVIALKNNQKSEPLIGRKKTVQKTPFV 1998
             G EY   ++A+      EPL      + K PFV
Sbjct: 17481 GNEYVFRIMAVNKYGVGEPL-ESAPVLMKNPFV 17512



 Score = 93.6 bits (231), Expect = 2e-18
 Identities = 287/1440 (19%), Positives = 522/1440 (36%), Gaps = 175/1440 (12%)

Query: 675   VVYEGQLISIQQYGHQEVTRFDFTTTSTS--TPVTSNTVTGETT--PFSPLVATSESVTE 730
             +  E   I++++    +  R++ T  ++S  T    N V  +    P  P+V     +++
Sbjct: 20222 ITAENLTINLKESVTADAGRYEITAANSSGTTKAFINIVVLDRPGPPTGPVV-----ISD 20276

Query: 731   ITASSFVVSWVSAS-DTVSGFRVEYELSEEGDEPQYLDLPSTA--TSVNIPDLLPGRKY- 786
             IT  S  + W     D  S       L  E     + ++ +T   T + +  L  G +Y 
Sbjct: 20277 ITEESVTLKWEPPKYDGGSQVTNYILLKRETSTAVWTEVSATVARTMMKVMKLTTGEEYQ 20336

Query: 787   ----IVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYR 842
                   N + IS+  + + +      T P  P  P V  V   SI V W  P +   G  
Sbjct: 20337 FRIKAENRFGISDHIDSACVTVKLPYTTPGPPSTPWVTNVTRESITVGWHEPVS--NGGS 20394

Query: 843   IVYSPSVEGSSTELNLPETANSVTL-------SDLQPGVQYNITIYAVEENQESTPVVIQ 895
              V    +E       L + AN + +       + +  G+ Y   +YA        P    
Sbjct: 20395 AVVGYHLEMKDRNSILWQKANKLVIRTTHFKVTTISAGLIYEFRVYAENAAGVGKP---S 20451

Query: 896   QETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPVNLPGEHG 951
               +      D    PR+++  +++   V++ W  P     S +TGY V+    +LP    
Sbjct: 20452 HPSEPVLAIDACEPPRNVRITDISKNSVSLSWQQPAFDGGSKITGYIVE--RRDLPDGRW 20509

Query: 952   QRLPISRNTFAE--VTGLSPGVTYYFKVFAVSH-GRESKPL-TAQQTTKLDAPTNLQFVN 1007
              +   +  T  +  ++GL+    Y F+VFA +  G  S P       T +D+        
Sbjct: 20510 TKASFTNVTETQFIISGLTQNSQYEFRVFARNAVGSISNPSEVVGPITCIDSYGGPVIDL 20569

Query: 1008  ETDSTVLVRWTPPRAQITGYRLTVGLTRRGQP--RQYNVGPSVSKYPLRNLQPASEYTVS 1065
               + T +V++       T  +L  G++ +  P    Y     +    L  ++  ++    
Sbjct: 20570 PLEYTEVVKYRAG----TSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLASI 20625

Query: 1066  LV-------------AIKGNQESPKATGVFTTL-QPGSSIPPYNTE-VTETTIVITW-TP 1109
             L+              ++    S  AT     L +PG    P   + VT   I + W  P
Sbjct: 20626 LIKDADRLNSGCYELKLRNAMGSASATIRVQILDKPGPPGGPIEFKTVTAEKITLLWRPP 20685

Query: 1110  APRIGFKLGVRPSQGGEAPREVTS------DSGSIVVSGLTPGVEYVYTIQVLR-----D 1158
             A   G K+     +  E  R V S      +   I  + +  G EY++ ++ +      +
Sbjct: 20686 ADDGGAKITHYIVEKRETSRVVWSMVSEHLEECIITTTKIIKGNEYIFRVRAVNKYGIGE 20745

Query: 1159  GQERDAPIV-NKVVTPLSP--PTNLHLEANPDTGVLTVSWERSTT---PDITGYRITTTP 1212
               E D+ +  N  VTP  P  P    +  N     +TV W R       DI+GY +    
Sbjct: 20746 PLESDSVVAKNAFVTPGPPGIPEVTKITKNS----MTVVWSRPIADGGSDISGYFLEKRD 20801

Query: 1213  TNGQQG-NSLEEVVHADQSSCTFDNLSPGLEYNVSVYTV--------KDDKESVPISDTI 1263
                      L+E +   +   T   L+   +Y   V  V         +  E    +D I
Sbjct: 20802 KKSLGWFKVLKETIRDTRQKVT--GLTENSDYQYRVCAVNAAGQGPFSEPSEFYKAADPI 20859

Query: 1264  IPAVPPPTDLRFTNIGPDTMRVTWAPP---PSIDLTNFLVRYSPVKNEE-DVAELSISPS 1319
              P   PP  +R  +    ++ + W+ P       +T ++V     + EE           
Sbjct: 20860 DPP-GPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVVEIRQGEEEEWTTVSTKGEVR 20918

Query: 1320  DNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQ----KTGLDSPTGIDFSDITANSFT 1375
                 V++NL PG  Y   VS+V    +  P+   +    K  L++P  ID       S  
Sbjct: 20919 TTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQAKDILEAPE-IDLDVALRTSVI 20977

Query: 1376  VHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSI---------TLTNLTPGT--EY 1424
                      +  ++ R  P     +  ++    +R SI         T+  +T     +Y
Sbjct: 20978 AKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKY 21037

Query: 1425  VVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGE 1484
             +++I    G  +S  +  +        + L+V   +  ++ + WD P +      I Y  
Sbjct: 21038 ILTIENGVGEPKSSTVSVKVLDTPAACQKLQVKHVSRGTVTLLWDPPLIDGGSPIINYVI 21097

Query: 1485  TGGNSPVQEFTVPGSKSTATISGL-----KPGVDYTITVYAVTGRGDSPASSKPISINYR 1539
                ++  + ++V   K ++T   L     K    + +      G G+   +++P+     
Sbjct: 21098 EKRDATKRTWSVVSHKCSSTSFKLIDLSEKTPFFFRVLAENEIGIGEPCETTEPVK---A 21154

Query: 1540  TEIDKP-SQMQVTDVQDNSISVKW----LPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQ 1594
              E+  P   + + D    S+ + W        S +T Y V    + G G      AG  +
Sbjct: 21155 AEVPAPIRDLSMKDSTKTSVILSWTKPDFDGGSVITEYVV---ERKGKGEQTWSHAGISK 21211

Query: 1595  T-EMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFT-DVDVDSIKIAW 1652
             T E+ +  L+        V+A+N  G S P+    +T     K L  T +VD+  I  A 
Sbjct: 21212 TCEIEVSQLKEQSVLEFRVFAKNEKGLSDPVTIGPIT----VKELIITPEVDLSDIPGAQ 21267

Query: 1653  ESPQ-GQVSRYRVTY-SSPEDGIHEL---FPAPDGE-------EDTAELQGLRPGSEYTV 1700
              + + G      + Y   P+  I  L    P  + E       E+   L       E+  
Sbjct: 21268 VTVRIGHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGG 21327

Query: 1701  SVVALHDDMESQPLIGTQSTAIPAPT----DLKFTQVTPTSLSAQWTPP----NVQLTGY 1752
                 + D+   +  +      +  P+     ++F ++   S+   W  P      ++T Y
Sbjct: 21328 KYTVILDNAVCRIAVPITVITLGPPSKPKGPIRFDEIKADSVILSWDVPEDNGGGEITCY 21387

Query: 1753  RVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLE 1812
              +      +T   K +  +   ++  V  L+   +Y+  V A      S+P    +   +
Sbjct: 21388 SIEKRETSQTN-WKMVCSSVARTTFKVPNLVKDAEYQFRVRAENRYGVSQPLVSSIIVAK 21446

Query: 1813  N----VSPPRRARVTDATETTITISWRTKT----ETITGFQVDAVPANGQTPIQRTIKP- 1863
             +      PP +  + + T   ++++W          +TGF V+    N     +    P 
Sbjct: 21447 HQFRIPGPPGKPVIYNVTSDGMSLTWDAPVYDGGSEVTGFHVEKKERNSILWQKVNTSPI 21506

Query: 1864  DVRSYTITGLQPGTDYKIYLYTLNDNARSSP----VVIDASTAIDAPSNLRFLATTPNSL 1919
               R Y  TGL  G DY+  +Y  N    SSP        A + +D P    ++  T  ++
Sbjct: 21507 SGREYRATGLVEGLDYQFRVYAENSAGLSSPSDPSKFTLAVSPVDPPGTPDYIDVTRETI 21566

Query: 1920  LVSWQPP----RARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIA 1975
              + W PP     ++I GY I+ ++ G+              + T+TGL PG  Y   +IA
Sbjct: 21567 TLKWNPPLRDGGSKIVGYSIE-KRQGNERWVRCNFTDVSECQYTVTGLSPGDRYEFRIIA 21625



 Score = 92.8 bits (229), Expect = 3e-18
 Identities = 271/1344 (20%), Positives = 470/1344 (34%), Gaps = 199/1344 (14%)

Query: 628   IQWNAPQPS---HISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISI 684
             I W  P  +    IS YI+  R   +   W   +      +  I  LK G  Y+ ++ + 
Sbjct: 18119 ISWEPPAYTGGCQISNYIVEKRDTTTT-TWHMVSATVARTTIKITKLKTGTEYQFRIFAE 18177

Query: 685   QQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSAS 744
              +YG              S P+ S  V  +     P    +  VT I+    +V W    
Sbjct: 18178 NRYGK-------------SAPLDSKAVIVQYPFKEPGPPGTPFVTSISKDQMLVQWHEPV 18224

Query: 745   DTVSGFRVEYELSE-EGDEPQYLDLPSTA---TSVNIPDLLPGRKYI--VNVYQISEDGE 798
             +      + Y L + E +   ++ L  T    T      L  G +Y   V+   I   G+
Sbjct: 18225 NDGGTKIIGYHLEQKEKNSILWVKLNKTPIQDTKFKTTGLDEGLEYEFKVSAENIVGIGK 18284

Query: 799   QSLILSTSQTTAPDAPPD-PTVDQVDDTSIVVRWSRPQ----APITGYRIVYSPSVEG-- 851
              S +        P  PP  P    +   ++ ++W +P     + ITGY +      +G  
Sbjct: 18285 PSKVSECFVARDPCDPPGRPEAIVITRNNVTLKWKKPAYDGGSKITGYIVEKKDLPDGRW 18344

Query: 852   -SSTELNLPETANSVTLSDLQPGVQYNITIYA------VEENQESTPVVIQQETTGTPRS 904
               ++  N+ ET    T+S L    +Y   + A        E  +S+  +  ++    P +
Sbjct: 18345 MKASFTNVLET--EFTVSGLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARDEIDAPNA 18402

Query: 905   DTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPG----EHGQRLPISRNT 960
                P  +D+  V   +  V       E+ + G  +  +  +  G    E   R+ I ++T
Sbjct: 18403 SLDPKYKDVIVVHAGETFVL------EADIRGKPIPDVVWSKDGKELEETAARMEI-KST 18455

Query: 961   FAEVTGL------SPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTN-LQFVNETDSTV 1013
               + T +      + G  Y  K+  V  G +S P+T +   +   P   L+    T    
Sbjct: 18456 IQKTTLVVKDCIRTDGGQYILKLSNVG-GTKSIPITVKVLDRPGPPEGPLKVTGVTAEKC 18514

Query: 1014  LVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAI 1069
              + W PP     A I+ Y +    T R    Q +       Y +  L P +EY   ++A+
Sbjct: 18515 YLAWNPPLQDGGANISHYIIEKRETSRLSWTQVSTEVQALNYKVTKLLPGNEYIFRVMAV 18574

Query: 1070  -KGNQESPKATGVFTTLQP----GSSIPPYNTEVTETTIVITWTP------APRIGFKLG 1118
              K     P  +G  T   P    G    P  + +T+ ++V+TW            G+ L 
Sbjct: 18575 NKYGIGEPLESGPVTACNPYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILE 18634

Query: 1119  VRPSQGGEAPR--EVTSDSGSIVVSGLTPGVEYVYTIQVLRD---GQERDAPIVNKVVTP 1173
              R  +G    +  + T     + V+GLT G  Y + +        G+  +  +  +    
Sbjct: 18635 KRDKEGVRWTKCNKKTLTDLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRACDA 18694

Query: 1174  LSPPTNLHLEANPDTGVLTVS--WERSTTPD---ITGYRI-----------TTTPTNGQQ 1217
             L PP         DT   +VS  W +        + GY +           T TP  G Q
Sbjct: 18695 LYPPGPPSNPKVTDTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAADEWTTCTPPTGLQ 18754

Query: 1218  GNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDD----KESVPISDTIIPAVPPP--- 1270
             G              T   L    EYN  +  +  +      ++P S      + PP   
Sbjct: 18755 GKQF-----------TVTKLKENTEYNFRICAINSEGVGEPATLPGSVVAQERIEPPEIE 18803

Query: 1271  --TDLRFTNI--GPDTMR----VTWAPPPSIDLTNFLVRYSPVKNE-EDVAELSISPSDN 1321
                DLR   +     T+R    +   P P        V++   +    D A++ ++ S  
Sbjct: 18804 LDADLRKVVVLRASATLRLFVTIKGRPEPE-------VKWEKAEGILTDRAQIEVTSSFT 18856

Query: 1322  AVVLTNLLPGTEYVVSVSSVYEQHESTP-LRGRQKTGLDSPTGIDFSDITANSFTVHWIA 1380
              +V+ N+        +++        T  +  R      +P  +   ++  +S T+ W  
Sbjct: 18857 MLVIDNVTRFDSGRYNLTLENNSGSKTAFVNVRVLDSPSAPVNLTIREVKKDSVTLSWEP 18916

Query: 1381  PR----ATITGYRIRHHPEHFSGRPREDRVPHS--RNSITLTNLTPGTEYVVSIVALNGR 1434
             P     A IT Y +       + R     + ++  + +  + NL  G  Y   ++A N  
Sbjct: 18917 PLIDGGAKITNYIVEKRE---TTRKAYATITNNCTKTTFRIENLQEGCSYYFRVLASNEY 18973

Query: 1435  EES-PLLIGQQSTVSDVPRD---LEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSP 1490
                 P    +   VS+ P     + +V  T  +  I W+ P            E+ G S 
Sbjct: 18974 GIGLPAETTEPVKVSEPPLPPGRVTLVDVTRNTATIKWEKP------------ESDGGSK 19021

Query: 1491  VQEFTVP----GSKS----------TATISGLKPGVDYTITVYAVTGRGDSPASSKPISI 1536
             +  + V     GS+            ATISGL  G +Y   V AV  +G S      + +
Sbjct: 19022 ITGYVVEMQTKGSEKWSTCTQVKTLEATISGLTAGEEYVFRVAAVNEKGRSDPRQLGVPV 19081

Query: 1537  NYRTEIDKPSQMQVTDVQDNSISVK---WLPSSSPVTGYRVTTTPKNGPGPTKTKT---- 1589
               R    KPS     ++  ++ +VK    L    P  G    T      G T  +T    
Sbjct: 19082 IARDIEIKPS----VELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVN 19137

Query: 1590  --AGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKG-LAFTDVDVD 1646
               +    T ++I+           +   N +G     +   V +   P G +   +V  D
Sbjct: 19138 VSSSKTVTSLSIKEASKEDVGTYELCVSNSAGSITVPITIIVLDRPGPPGPIRIDEVSCD 19197

Query: 1647  SIKIAWESPQ----GQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSV 1702
             SI I+W  P+     Q+S Y V           +  +      + ++  L  GSEY   V
Sbjct: 19198 SITISWNPPEYDGGCQISNYIVEKKETTSTTWHIV-SQAVARTSIKIVRLTTGSEYQFRV 19256

Query: 1703  VALH-----DDMESQPLIGTQSTAIPAPTDL-KFTQVTPTSLSAQWTPP----NVQLTGY 1752
              A +        ES  ++     + P P    K    T +++   W  P      ++ GY
Sbjct: 19257 CAENRYGKSSYSESSAVVAEYPFSPPGPPGTPKVVHATKSTMLVTWQVPVNDGGSRVIGY 19316

Query: 1753  RVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGV--VTT 1810
              +    +      K   +    + + VSGL     YE  VYA       + ++    V  
Sbjct: 19317 HLEYKERSSILWSKANKILIADTQMKVSGLDEGLMYEYRVYAENIAGIGKCSKSCEPVPA 19376

Query: 1811  LENVSPPRRARVTDATETTITISW 1834
              +   PP +  VT+ T  ++++ W
Sbjct: 19377 RDPCDPPGQPEVTNITRKSVSLKW 19400



 Score = 92.0 bits (227), Expect = 6e-18
 Identities = 265/1345 (19%), Positives = 470/1345 (34%), Gaps = 186/1345 (13%)

Query: 814   PPDPTVD--QVDDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTL 867
             PP P  D   +D  +  + W  P     + IT Y +       G         T  S  +
Sbjct: 12689 PPQPPFDISDIDADACSLSWHIPLEDGGSNITNYIVEKCDVSRGDWVTALASVTKTSCRV 12748

Query: 868   SDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPS-PRDLQFVEVTDVKVTIM 926
               L PG +Y   + A      S P+   +     P    VPS P++ +  +V    + + 
Sbjct: 12749 GKLIPGQEYIFRVRAENRFGISEPLTSPKMVAQFPFG--VPSEPKNARVTKVNKDCIFVA 12806

Query: 927   WTPPES----AVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSH 982
             W  P+S     + GY ++    N          + R+T     GL  G+ Y F+++A++ 
Sbjct: 12807 WDRPDSDGGSPIIGYLIERKERNSLLWVKANDTLVRSTEYPCAGLVEGLEYSFRIYALNK 12866

Query: 983   GRESKPL--TAQQTTKL--DAPTNLQFVNETDSTVLVRWTPPR----AQITGYRLTVGLT 1034
                S P   T   T ++  D P   + ++ T STV + W  P+    ++I GY +     
Sbjct: 12867 AGSSPPSKPTEYVTARMPVDPPGKPEVIDVTKSTVSLIWARPKHDGGSKIIGYFVEACKL 12926

Query: 1035  RRGQPRQYNVGPSV---SKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSI 1091
                +  + N  P      +Y    L+  ++Y    +A      SP +           ++
Sbjct: 12927 PGDKWVRCNTAPHQIPQEEYTATGLEEKAQYQFRAIARTAVNISPPSEPSDPVTILAENV 12986

Query: 1092  PP----------YNTEVTETTIVITWT----PAPRIGFKLG---VRPSQGGEAPREVTSD 1134
             PP            T    T + +  T    P P + +K     ++P++G +   +   +
Sbjct: 12987 PPRIDLSVAMKSLLTVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQ--RN 13044

Query: 1135  SGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVS 1194
               ++ +  +       YTI        + A I  KV+    PP ++ +        + +S
Sbjct: 13045 LCTLELFSVNRKDSGDYTITAENSSGSKSATIKLKVLDKPGPPASVKINKMYSDRAM-LS 13103

Query: 1195  WE---RSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVK 1251
             WE        +IT Y +    T+      +   V    +SC+ + L  G EY   +    
Sbjct: 13104 WEPPLEDGGSEITNYIVDKRETSRPNWAQVSATVPI--TSCSVEKLIEGHEYQFRICAEN 13161

Query: 1252  DDKESVPI-SDTIIPAVP--------PPTDLRFTNIGPDTMRVTWAPPPS---IDLTNFL 1299
                   P+ ++  I   P        PP     +NI  D M V+W PP       +T +L
Sbjct: 13162 KYGVGDPVFTEPAIAKNPYDPPGRCDPPV---ISNITKDHMTVSWKPPADDGGSPITGYL 13218

Query: 1300  V--RYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTG 1357
             +  R +   N   V    I   +  +  T L  GTEY   V+++ +     P    +   
Sbjct: 13219 LEKRETQAVNWTKVNRKPII--ERTLKATGLQEGTEYEFRVTAINKAGPGKPSDASKAAY 13276

Query: 1358  LDSP-------TGIDFSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPREDRV 1406
                P             D T +S ++ W  P     + I GY +           R +  
Sbjct: 13277 ARDPQYPPGPPAFPKVYDTTRSSVSLSWGKPAYDGGSPIIGYLVEVKRADSDNWVRCNLP 13336

Query: 1407  PH-SRNSITLTNLTPGTEYVVSIVALNGREES-PLLIGQQSTVSDV--PRDLEVVAATPT 1462
              +  +    +T L   T+Y   + A+N    S P  +  +    D+  P + E+ A    
Sbjct: 13337 QNLQKTRFEVTGLMEDTQYQFRVYAVNKIGYSDPSDVPDKHYPKDILIPPEGELDADLRK 13396

Query: 1463  SLLISWDAPAVTVRYY---------RITYGETGGNSPVQEFTVPGSKSTATISGLKPGVD 1513
             +L++      VT+R Y         +IT+ +   N   +      S    T    +    
Sbjct: 13397 TLILR---AGVTMRLYVPVKGRPPPKITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNK 13453

Query: 1514  YTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLP----SSSPV 1569
             Y    Y +T           I +        P  + V ++  +S  V W P      SP+
Sbjct: 13454 YDAGKYILTLENSCGKKEYTIVVKVLDTPGPPVNVTVKEISKDSAYVTWEPPIIDGGSPI 13513

Query: 1570  TGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAV 1629
               Y V            T T    +T   +  L+    Y   V+A+N  G   P      
Sbjct: 13514 INYVVQKRDAERKS-WSTVTTECSKTSFRVANLEEGKSYFFRVFAENEYGIGDPGETRDA 13572

Query: 1630  TNIDRPKG----LAFTDVDVDSIKIAWESPQG----QVSRYRVTYSSPEDGIHELFPAPD 1681
                 +  G    L    V   S  I W+ P      ++  Y V + + E+    +  +  
Sbjct: 13573 VKASQTPGPVVDLKVRSVSKSSCSIGWKKPHSDGGSRIIGYVVDFLTEENKWQRVMKSLS 13632

Query: 1682  GEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQ 1741
              +    +L     G EYT  V A +++ E  P        + A  D     V    L  +
Sbjct: 13633 LQYSAKDLT---EGKEYTFRVSAENENGEGTP----SEITVVARDD-----VVAPDLDLK 13680

Query: 1742  WTPPNVQL----TGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKD 1797
               P    L    + +R+++  K K  P        D        L   T+  V   A+  
Sbjct: 13681 GLPDLCYLAKENSNFRLKIPIKGKPAPSVSWKKGEDP-------LATDTRVSVESSAVNT 13733

Query: 1798  TLTSRPAQ----GVVT-TLENVSPPRRARVT-----------------DATETTITISWR 1835
             TL     Q    G  T TL+NV+  +   ++                 + T   +T+ W 
Sbjct: 13734 TLIVYDCQKSDAGKYTITLKNVAGTKEGTISIKVVGKPGIPTGPIKFDEVTAEAMTLKWA 13793

Query: 1836  TKTET----ITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYL-----YTL 1886
                +     IT + ++   +     +         ++ +T L  G +Y   +     Y +
Sbjct: 13794 PPKDDGGSEITNYILEKRDSVNNKWVTCASAVQKTTFRVTRLHEGMEYTFRVSAENKYGV 13853

Query: 1887  NDNARSSPVVIDASTAI-DAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPG 1941
              +  +S P+V      + DAP     +    +S+ ++W  P+    + ITGY +++++  
Sbjct: 13854 GEGLKSEPIVARHPFDVPDAPPPPNIVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKERN 13913

Query: 1942  SPPREVVPRPRPGVTEATITGLEPGTEYTIYVIAL------KNNQKSEPLI--------G 1987
             S   +   +    + +  +TGL  G EY   V+A+      K +  SEP++        G
Sbjct: 13914 SLLWKRANKTPIRMRDFKVTGLTEGLEYEFRVMAINLAGVGKPSLPSEPVVALDPIDPPG 13973

Query: 1988  RKKTV-----QKTPFVTHPGYDTGN 2007
             + + +       T   T P YD G+
Sbjct: 13974 KPEVINITRNSVTLIWTEPKYDGGH 13998



 Score = 91.7 bits (226), Expect = 8e-18
 Identities = 294/1501 (19%), Positives = 530/1501 (35%), Gaps = 198/1501 (13%)

Query: 628   IQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISI 684
             + W  P     S I+ Y+L  R   +V   K    P    +    GL+ G  YE ++ +I
Sbjct: 13201 VSWKPPADDGGSPITGYLLEKRETQAVNWTKVNRKPIIERTLKATGLQEGTEYEFRVTAI 13260

Query: 685   QQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSW---- 740
              + G  + +              S         + P       V + T SS  +SW    
Sbjct: 13261 NKAGPGKPSD------------ASKAAYARDPQYPPGPPAFPKVYDTTRSSVSLSWGKPA 13308

Query: 741   VSASDTVSGFRVEYELSEEGDEPQYLDLPST--ATSVNIPDLLPGRKYIVNVYQISEDGE 798
                   + G+ VE + + + D     +LP     T   +  L+   +Y   VY +++ G 
Sbjct: 13309 YDGGSPIIGYLVEVKRA-DSDNWVRCNLPQNLQKTRFEVTGLMEDTQYQFRVYAVNKIG- 13366

Query: 799   QSLILSTSQTTAPD--------APPDPTVDQVDDTSIVVR---WSRPQAPITGYRIVYSP 847
                   +  +  PD         PP+  +D     ++++R     R   P+ G      P
Sbjct: 13367 -----YSDPSDVPDKHYPKDILIPPEGELDADLRKTLILRAGVTMRLYVPVKGRP---PP 13418

Query: 848   SVEGSSTELNLPETAN-SVTLSDLQPGV-----------QYNITIYAVEENQESTPVVIQ 895
              +  S   +NL +     +  +D    +           +Y +T+      +E T VV  
Sbjct: 13419 KITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKYILTLENSCGKKEYTIVVKV 13478

Query: 896   QETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPGEHG 951
              +T G P + TV         E++     + W PP     S +  Y V            
Sbjct: 13479 LDTPGPPVNVTVK--------EISKDSAYVTWEPPIIDGGSPIINYVVQKRDAERKSWST 13530

Query: 952   QRLPISRNTFAEVTGLSPGVTYYFKVFAVSH---GRESKPLTAQQTTKLDAP-TNLQFVN 1007
                  S+ +F  V  L  G +Y+F+VFA +    G   +   A + ++   P  +L+  +
Sbjct: 13531 VTTECSKTSF-RVANLEEGKSYFFRVFAENEYGIGDPGETRDAVKASQTPGPVVDLKVRS 13589

Query: 1008  ETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYT 1063
              + S+  + W  P     ++I GY +   LT   + ++     S+ +Y  ++L    EYT
Sbjct: 13590 VSKSSCSIGWKKPHSDGGSRIIGYVVDF-LTEENKWQRVMKSLSL-QYSAKDLTEGKEYT 13647

Query: 1064  VSLVAIKGNQE-SPKATGVFT---TLQPG---SSIPPYNTEVTETT-----IVITWTPAP 1111
               + A   N E +P    V      + P      +P       E +     I I   PAP
Sbjct: 13648 FRVSAENENGEGTPSEITVVARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPIKGKPAP 13707

Query: 1112  RIGFKLGVRP-SQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKV 1170
              + +K G  P +       E ++ + +++V          YTI +      ++  I  KV
Sbjct: 13708 SVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKEGTISIKV 13767

Query: 1171  VTPLSPPTNLHLEANPDTGVLTVSW---ERSTTPDITGYRITTTPTNGQQGNSLEEVVHA 1227
             V     PT            +T+ W   +     +IT Y +    +   +  +    V  
Sbjct: 13768 VGKPGIPTGPIKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDSVNNKWVTCASAV-- 13825

Query: 1228  DQSSCTFDNLSPGLEYNVSV-----YTVKDDKESVPI---SDTIIPAVPPPTDLRFTNIG 1279
              +++     L  G+EY   V     Y V +  +S PI       +P  PPP ++   ++ 
Sbjct: 13826 QKTTFRVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVPDAPPPPNI--VDVR 13883

Query: 1280  PDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVA-----ELSISPSDNAVVLTNLLPGTEY 1334
              D++ +TW  P     +     +   K    +      +  I   D  V  T L  G EY
Sbjct: 13884 HDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTPIRMRDFKV--TGLTEGLEY 13941

Query: 1335  VVSVSSVYEQHESTPLRGRQKT----GLDSPTGIDFSDITANSFTVHWIAPR----ATIT 1386
                V ++       P    +       +D P   +  +IT NS T+ W  P+      +T
Sbjct: 13942 EFRVMAINLAGVGKPSLPSEPVVALDPIDPPGKPEVINITRNSVTLIWTEPKYDGGHKLT 14001

Query: 1387  GYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN--GREESPLLIGQQ 1444
             GY +           + + V     + T+T+L  G +Y   I A N  G   +P     +
Sbjct: 14002 GYIVEKRDLPSKSWMKANHVNVPECAFTVTDLVEGGKYEFRIRAKNTAGAISAP----SE 14057

Query: 1445  STVSDVPRDLEVVAATPTSLLISWDAPAVTVR----------------YYRITYGETGGN 1488
             ST + + +D       PT +L       +T++                  + ++ + G +
Sbjct: 14058 STETIICKD---EYEAPTIVLDPTIKDGLTIKAGDTIVLNAISILGKPLPKSSWSKAGKD 14114

Query: 1489  SPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQM 1548
                 + T   S  T+++  +K         Y +T         + + +        P  +
Sbjct: 14115 IRPSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFGTKVEHVKVTVLDVPGPPGPV 14174

Query: 1549  QVTDVQDNSISVKWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQP 1604
             ++++V     ++ W P      SP+  Y +     +    T           +  + +Q 
Sbjct: 14175 EISNVSAEKATLTWTPPLEDGGSPIKSYILEKRETSRLLWTVVSEDIQSCRHVATKLIQG 14234

Query: 1605  TVEYVVSVYAQNPSGESQPLVQTAVTNIDR------PKGLAFTDVDVDSIKIAWESP--- 1655
               EY+  V A N  G+ +P+    V  +DR      P+    ++V  ++  ++W+ P   
Sbjct: 14235 N-EYIFRVSAVNHYGKGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSWKRPVDD 14293

Query: 1656  -QGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVA-----LHDDM 1709
                +++ Y V     +             +   ++ GL+ GS Y   V A     +    
Sbjct: 14294 GGSEITGYHVERREKKSLRWVRAIKTPVSDLRCKVTGLQEGSTYEFRVSAENRAGIGPPS 14353

Query: 1710  ESQPLIGTQSTAIP--APTDLKFTQVTPTSLSAQWTPPN----VQLTGYRVRVTPKEKTG 1763
             E+   +  +  A P   P++   T  T  S S  W  P+    +++TGY   V   +K G
Sbjct: 14354 EASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLAWGKPHYDGGLEITGY---VVEHQKVG 14410

Query: 1764  PMKEI----NLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRR 1819
                 I      A   +  VV  L    KY   + A+ D     PA  V+  +E V     
Sbjct: 14411 DEAWIKDTTGTALRITQFVVPDLQTKEKYNFRISAINDAGVGEPA--VIPDVEIVEREMA 14468

Query: 1820  ARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIK-------PDVRSYTITG 1872
                    E   T+  R          +   PA   T  +  I         +  S+T+  
Sbjct: 14469 PDFELDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKNRANIENTESFTLLI 14528

Query: 1873  LQPGTDYKI--YLYTLNDNARSSPVVIDASTAIDAPS---NLRFLATTPNSLLVSWQPP- 1926
             +     Y    ++ T+ + A      ++    +D P    NLR    T +S+ + W  P 
Sbjct: 14529 IPECNRYDTGKFVMTIENPAGKKSGFVNV-RVLDTPGPVLNLRPTDITKDSVTLHWDLPL 14587

Query: 1927  ---RARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSE 1983
                 +RIT YI++ ++  +         +       +TGL  G EY   V+A       E
Sbjct: 14588 IDGGSRITNYIVE-KREATRKSYSTATTKCHKCTYKVTGLSEGCEYFFRVMAENEYGIGE 14646

Query: 1984  P 1984
             P
Sbjct: 14647 P 14647



 Score = 90.9 bits (224), Expect = 1e-17
 Identities = 273/1318 (20%), Positives = 459/1318 (34%), Gaps = 189/1318 (14%)

Query: 771   TATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPP---DPTVDQVDDTSI 827
             ++TS  + DL     +   V   +E G      +T    A + P    D ++     TS+
Sbjct: 21115 SSTSFKLIDLSEKTPFFFRVLAENEIGIGEPCETTEPVKAAEVPAPIRDLSMKDSTKTSV 21174

Query: 828   VVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAV 883
             ++ W++P     + IT Y +      E + +   + +T   + +S L+        ++A 
Sbjct: 21175 ILSWTKPDFDGGSVITEYVVERKGKGEQTWSHAGISKTCE-IEVSQLKEQSVLEFRVFAK 21233

Query: 884   EENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIP 943
              E   S PV I   T      + + +P ++   ++   +VT+           Y+    P
Sbjct: 21234 NEKGLSDPVTIGPITV----KELIITP-EVDLSDIPGAQVTVRIGHNVHLELPYKGKPKP 21288

Query: 944   VNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTN- 1002
                  + G  LP+  + F   +     +T   K     HG +   +      ++  P   
Sbjct: 21289 SISWLKDG--LPLKESEFVRFSKTENKITLSIKNAKKEHGGKYTVILDNAVCRIAVPITV 21346

Query: 1003  ------------LQFVNETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGP 1046
                         ++F      +V++ W  P      +IT Y +    T +   +      
Sbjct: 21347 ITLGPPSKPKGPIRFDEIKADSVILSWDVPEDNGGGEITCYSIEKRETSQTNWKMVCSSV 21406

Query: 1047  SVSKYPLRNLQPASEYTVSLVAI-KGNQESPKATGVFTTLQ----PGSSIPPYNTEVTET 1101
             + + + + NL   +EY   + A  +     P  + +         PG    P    VT  
Sbjct: 21407 ARTTFKVPNLVKDAEYQFRVRAENRYGVSQPLVSSIIVAKHQFRIPGPPGKPVIYNVTSD 21466

Query: 1102  TIVITWTP------APRIGFKLGVRPSQGGEAPREVTSD-SG-SIVVSGLTPGVEYVYTI 1153
              + +TW        +   GF +  +        +  TS  SG     +GL  G++Y + +
Sbjct: 21467 GMSLTWDAPVYDGGSEVTGFHVEKKERNSILWQKVNTSPISGREYRATGLVEGLDYQFRV 21526

Query: 1154  QVLRDG---QERDAPIVNKVVTPLSPP-TNLHLEANPDTGVLTVSWE---RSTTPDITGY 1206
                         D       V+P+ PP T  +++   +T  +T+ W    R     I GY
Sbjct: 21527 YAENSAGLSSPSDPSKFTLAVSPVDPPGTPDYIDVTRET--ITLKWNPPLRDGGSKIVGY 21584

Query: 1207  RITTTPTNGQQGNSL-EEVVHADQSSC--TFDNLSPGLEYNV------SVYTVKDDKESV 1257
              I       +QGN         D S C  T   LSPG  Y        +V T+    +S 
Sbjct: 21585 SIEK-----RQGNERWVRCNFTDVSECQYTVTGLSPGDRYEFRIIARNAVGTISPPSQSS 21639

Query: 1258  PISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNE---EDVAEL 1314
              I  T    VPP         GP+                 LV+  PV      +D  E+
Sbjct: 21640 GIIMTRDENVPP-----IVEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVTWFKDGVEI 21694

Query: 1315  SISPSDNAVVLTNLLPGTEYVV--------SVSSVYEQHESTPLRGRQKTGLDSPTG--- 1363
                 +   + +T++L  T   V         V +V  ++ S   +   K  +    G   
Sbjct: 21695 EKRMN---MEITDVLGSTSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQDTPGKVV 21751

Query: 1364  --IDFSDITANSFTVHWIAPR----ATITGYRI-RHHPEHFSGRPREDRVPHSRNSITLT 1416
               I F++IT    T+ W AP     A IT Y I +      +    ED+      S T  
Sbjct: 21752 GPIRFTNITGEKMTLWWDAPLNDGCAPITHYIIEKRETSRLAWALIEDKC--EAQSYTAI 21809

Query: 1417  NLTPGTEYVVSIVALN----GR--EESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDA 1470
              L  G EY   + A+N    GR  +  P++   Q TV D P   E    T  S+ ++W  
Sbjct: 21810 KLINGNEYQFRVSAVNKFGVGRPLDSDPVVAQIQYTVPDAPGIPEPSNITGNSITLTWAR 21869

Query: 1471  PAVTVRYYRITYGETGGNSPVQEFTV-----------------PGSKSTATISGLKPGVD 1513
             P            E+ G S +Q++ +                 P S++   ++GL  G +
Sbjct: 21870 P------------ESDGGSEIQQYILERREKKSTRWVKVISKRPISETRFKVTGLTEGNE 21917

Query: 1514  YTITVYAVTGRGDSPASSKPISINYRTEIDKPSQ---MQVTDVQDNSISVKW----LPSS 1566
             Y   V A    G  PAS     I  R  ++ P     ++VTD    ++S++W        
Sbjct: 21918 YEFHVMAENAAGVGPASGISRLIKCREPVNPPGPPTVVKVTDTSKTTVSLEWSKPVFDGG 21977

Query: 1567  SPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQ 1626
               + GY +     +     K       +T  T+  LQ   EY   V A N +G+      
Sbjct: 21978 MEIIGYIIEMCKADLGDWHKVNAEACVKTRYTVTDLQAGEEYKFRVSAINGAGKGDSCEV 22037

Query: 1627  TA-VTNIDRPKGLAFTDVDVDS-IKIAWESPQGQVSRYRVTY----------SSPEDGIH 1674
             T  +  +DR   L   ++D+D+  K       G   R  + Y          S P+  + 
Sbjct: 22038 TGTIKAVDR---LTAPELDIDANFKQTHVVRAGASIRLFIAYQGRPTPTAVWSKPDSNLS 22094

Query: 1675  ---ELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFT 1731
                ++         T E        +YT++V            +    T  P P  + F 
Sbjct: 22095 LRADIHTTDSFSTLTVENCNRNDAGKYTLTVENNSGSKSITFTVKVLDTPGP-PGPITFK 22153

Query: 1732  QVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKE----INLAPDSSSVVVSGLMVATK 1787
              VT  S +  W  P +   G R+     EK    +     I+         V+ L     
Sbjct: 22154 DVTRGSATLMWDAPLLD-GGARIHHYVVEKREASRRSWQVISEKCTRQIFKVNDLAEGVP 22212

Query: 1788  YEVSVYALKDTLTSRPAQ--GVVTTLENVSPPRRARVTDATETTITISW----RTKTETI 1841
             Y   V A+ +     P +    +   E  +PPRR  V D ++++  ++W          I
Sbjct: 22213 YYFRVSAVNEYGVGEPYEMPEPIVATEQPAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRI 22272

Query: 1842  TGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDAST 1901
             TG+ ++         ++      + ++T+  L   T+Y+  +   ND   S P    +S 
Sbjct: 22273 TGYLLEMRQKGSDFWVEAGHTKQL-TFTVERLVEKTEYEFRVKAKNDAGYSEPREAFSSV 22331

Query: 1902  AIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVP---RPRPGVT 1956
              I  P         P + L         IT  +I   K GSP    VP   RP P VT
Sbjct: 22332 IIKEPQ------IEPTADLTG-------ITNQLITC-KAGSPFTIDVPISGRPAPKVT 22375



 Score = 89.7 bits (221), Expect = 3e-17
 Identities = 260/1286 (20%), Positives = 475/1286 (36%), Gaps = 231/1286 (17%)

Query: 780  LLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPIT 839
            ++P ++Y++ V  ++  G       +    A D    PT+D      IV+   +   P+ 
Sbjct: 8045 VVPDKEYVLRVRAVNAIGVSEPSEISENVVAKDPDCKPTIDLETHDIIVIEGEKLSIPVP 8104

Query: 840  GYRIVYSPSV----EGSSTELNLPETANSVTLS---DLQPGVQYNITIYAV--EENQEST 890
             +R V  P+V    +G   + +   T  +  +S   ++   V+ +  IY +  E    S 
Sbjct: 8105 -FRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSA 8163

Query: 891  PVVIQQETTGTPRSDTVPSP-RDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGE 949
               I  +  G      +P P +D++  ++T     + W PPE    G    +  V    E
Sbjct: 8164 TASINVKVIG------LPGPCKDIKASDITKSSCKLTWEPPE--FDGGTPILHYVLERRE 8215

Query: 950  HGQR--LPI--SRNTFA-EVTGLSPGVTYYFKVFAVSH--GRE----SKPLTAQQTTKL- 997
             G+R  +P+    N  +  V  L P   Y+F+V AV+   G E      P+ AQ   +  
Sbjct: 8216 AGRRTYIPVMSGENKLSWTVKDLIPNGEYFFRVKAVNKVGGGEYIELKNPVIAQDPKQPP 8275

Query: 998  DAPTNLQFVNETDSTVLVRWTPPR----AQITGY---RLTVGLTRRGQPRQYNVGPSVSK 1050
            D P +++  N T   + + W PP     ++I GY   ++  G  R  +  ++ V   +  
Sbjct: 8276 DPPVDVEVHNPTAEAMTITWKPPLYDGGSKIMGYIIEKIAKGEERWKRCNEHLV--PILT 8333

Query: 1051 YPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPA 1110
            Y  + L+   EY   + A         A G+    +P  + PP        T  +    A
Sbjct: 8334 YTAKGLEEGKEYQFRVRA-------ENAAGIS---EPSRATPP--------TKAVDPIDA 8375

Query: 1111 PRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVL--RDGQERDAPIVN 1168
            P++  +  +   +G E   +  S SGS       P + ++    V+   + ++R AP+V 
Sbjct: 8376 PKVILRTSLEVKRGDEIALDA-SISGSPY-----PTITWIKDENVIVPEEIKKRAAPLVR 8429

Query: 1169 KVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHAD 1228
            +    +       L   P T  L++                    N ++G S   V    
Sbjct: 8430 RRKGEVQEEEPFVL---PLTQRLSID-------------------NSKKGESQLRVR--- 8464

Query: 1229 QSSCTFDNLSPGLEYNVSVYTVKDDK--ESVPISDTIIPAVPPPTDLRFTNIGPDTMRVT 1286
                  D+L P  ++ + +  V++D      P + +++    PP +  F +I   ++   
Sbjct: 8465 ------DSLRP--DHGLYMIKVENDHGIAKAPCTVSVLDTPGPPINFVFEDIRKTSVLCK 8516

Query: 1287 WAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHE 1346
            W PP   D  + ++ Y+  K ++        P    +V+T+ L   +Y  SV+ + E  E
Sbjct: 8517 WEPPLD-DGGSEIINYTLEKKDKT------KPDSEWIVVTSTLRHCKY--SVTKLIEGKE 8567

Query: 1347 ------------------STPLRGRQKTGL-DSPTGIDFSDITANSFTVHWIAPR---AT 1384
                              S PL  +   G  D+P      D+T+NS  V W  P+   + 
Sbjct: 8568 YLFRVRAENRFGPGPPCVSKPLVAKDPFGPPDAPDKPIVEDVTSNSMLVKWNEPKDNGSP 8627

Query: 1385 ITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN----GREESPLL 1440
            I GY +     + +   R ++   +     +  L  G  YV  + A N    G+   P  
Sbjct: 8628 ILGYWLEKREVNSTHWSRVNKSLLNALKANVDGLLEGLTYVFRVCAENAAGPGKFSPP-- 8685

Query: 1441 IGQQSTVSD--------VPRDLEVVAATPTSLLISWDAPAVT----VRYYRITYGETGGN 1488
                 T  D        +PR   V   + T++ + W+ PA      +  Y +     G N
Sbjct: 8686 -SDPKTAHDPISPPGPPIPR---VTDTSSTTIELEWEPPAFNGGGEIVGYFVDKQLVGTN 8741

Query: 1489 SPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDS-PASSKPISINYRTEIDKPSQ 1547
               +           T+  ++ G DY + V AV   G+  P  ++P+++    E  +P  
Sbjct: 8742 EWSRCTEKMIKVRQYTVKEIREGADYKLRVSAVNAAGEGPPGETQPVTV---AEPQEPPA 8798

Query: 1548 MQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTK--TKTAGP-DQTEMTIEGLQP 1604
            +++       +SVK           R+       P PTK  TK  G  D+  + I+ +  
Sbjct: 8799 VEL------DVSVKGGIQIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKDRVVIDNVGT 8852

Query: 1605 TVEYVVS-----------VYAQNPSGESQPLVQTAVTNIDRP-KGLAFTDVDVDSIKIAW 1652
              E ++            + A N  G      +  V ++  P   L     +     + W
Sbjct: 8853 KSELIIKDALRKDHGRYVITATNSCGSKFAAARVEVFDVPGPVLDLKPVVTNRKMCLLNW 8912

Query: 1653 ESPQ----GQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALH-- 1706
              P+     +++ + +     +  +H      + E    ++ GL  G EY   V+A +  
Sbjct: 8913 SDPEDDGGSEITGFIIERKDAK--MHTWRQPIETERSKCDITGLLEGQEYKFRVIAKNKF 8970

Query: 1707 ---DDMESQPLIGTQSTAIP-APTDLKFTQVTPTSLSAQWTPPNVQ----LTGYRVRVTP 1758
                 +E  P++       P +P  L +T+ T ++++  W  P       + GY +    
Sbjct: 8971 GCGPPVEIGPILAVDPLGPPTSPERLTYTERTKSTITLDWKEPRSNGGSPIQGYIIEKRR 9030

Query: 1759 KEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPA--QGVVTTLENVSP 1816
             +K    +       ++S +V  L     YE  V A+ +   S P+    VV   + V P
Sbjct: 9031 HDKPDFERVNKRLCPTTSFLVENLDEHQMYEFRVKAVNEIGESEPSLPLNVVIQDDEVPP 9090

Query: 1817 PRRARVTDATETTIT-------------------ISWRTKTETITGFQVDAVPANGQTPI 1857
              + R++   +T                      I W +K ET+     DA+    +   
Sbjct: 9091 TIKLRLSVRGDTIKVKAGEPVHIPADVTGLPMPKIEW-SKNETVIEKPTDALQITKEEVS 9149

Query: 1858 QRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAI-DAPSNLRFLATT- 1915
            +   K ++          GT      YT+  + R   V  +    + D PS  R LA T 
Sbjct: 9150 RSEAKTELSIPKAVREDKGT------YTVTASNRLGSVFRNVHVEVYDRPSPPRNLAVTD 9203

Query: 1916 --PNSLLVSWQPP----RARITGYII 1935
                S  ++W  P     + IT Y+I
Sbjct: 9204 IKAESCYLTWDAPLDNGGSEITHYVI 9229



 Score = 89.7 bits (221), Expect = 3e-17
 Identities = 320/1572 (20%), Positives = 568/1572 (36%), Gaps = 254/1572 (16%)

Query: 611   PVEVFITETPSQP----------NSHPIQWNAPQP---SHISKYILRWRPKNSVGRWKEA 657
             P  +  TE P+ P          +S  + W  P     S I+ Y+L  R K S   W EA
Sbjct: 22232 PEPIVATEQPAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGS-DFWVEA 22290

Query: 658   TIPGHLN--SYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNT--VTG 713
                GH    ++T++ L     YE ++ +    G+ E  R  F++     P    T  +TG
Sbjct: 22291 ---GHTKQLTFTVERLVEKTEYEFRVKAKNDAGYSE-PREAFSSVIIKEPQIEPTADLTG 22346

Query: 714   ETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTAT 773
              T       A S    ++  S      V+       +++E    +E D    +      T
Sbjct: 22347 ITNQLITCKAGSPFTIDVPISGRPAPKVT-------WKLEEMRLKETDRVS-ITTTKDRT 22398

Query: 774   SVNIPDLLPGR--KYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPT-VDQVDDTSIVVR 830
             ++ + D + G   +Y + +   +  G ++  ++      P     P  V  V   S V+ 
Sbjct: 22399 TLTVKDSMRGDSGRYFLTLENTA--GVKTFSVTVVVIGRPGPVTGPIEVSSVSAESCVLS 22456

Query: 831   WSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITI-----Y 881
             W  P+      IT Y +    S   +   +N       + ++ L   ++Y+  +     +
Sbjct: 22457 WGEPKDGGGTEITNYIVEKRESGTTAWQLVNSSVKRTQIKVTHLTKYMEYSFRVSSENRF 22516

Query: 882   AVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGY 937
              V +  ES P++ +      P + T P     +   V+   ++I W  P     S + GY
Sbjct: 22517 GVSKPLESAPIIAEHPFV-PPSAPTRP-----EVYHVSANAMSIRWEEPYHDGGSKIIGY 22570

Query: 938   RVDVIPVN-LPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFA-----VSHGRE-SKPLT 990
              V+    N +      ++P     + +VTGL  G+ Y F+ +A     VS   E S+P+ 
Sbjct: 22571 WVEKKERNTILWVKENKVPCLECNY-KVTGLVEGLEYQFRTYALNAAGVSKASEASRPIM 22629

Query: 991   AQQTTKLDAPTNLQFVNETDSTVLVRWTPPR----AQITGYRL----------------- 1029
             AQ    +DAP   +  + T STV + W+ P     +++ GY +                 
Sbjct: 22630 AQ--NPVDAPGRPEVTDVTRSTVSLIWSAPAYDGGSKVVGYIIERKPVSEVGDGRWLKCN 22687

Query: 1030  ---------TVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKAT- 1079
                      TV     G   ++ V   ++K     +   SE T   V  +     PKA  
Sbjct: 22688 YTIVSDNFFTVTALSEGDTYEFRV---LAKNAAGVISKGSEST-GPVTCRDEYAPPKAEL 22743

Query: 1080  -----GVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGE-APREVTS 1133
                  G   T++ GS +             +   P P+I +  G +     E    + T 
Sbjct: 22744 DARLHGDLVTIRAGSDL--------VLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTG 22795

Query: 1134  DSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTV 1193
                + V+          YT+ V      +   ++ KV+    P   L + +       T+
Sbjct: 22796 KRATAVIKFCDRSDSGKYTLTVKNASGTKAVSVMVKVLDSPGPCGKLTV-SRVTQEKCTL 22854

Query: 1194  SWERSTTPDITGYRITTTPTNGQQGNSLEEVV---HADQSSCTFDNLSPGLEYNVSVYTV 1250
             +W  S   +  G  IT      ++ + L  V+        S     L    EY   V  V
Sbjct: 22855 AW--SLPQEDGGAEITHYIVERRETSRLNWVIVEGECPTLSYVVTRLIKNNEYIFRVRAV 22912

Query: 1251  KDDKESVPISDTIIPA-----VP-PPTDLRFTNIGPDTMRVTWAPPPS---IDLTNFLV- 1300
                   VP+    I A     +P PP        G + + + W  P S    +++N+LV 
Sbjct: 22913 NKYGPGVPVESEPIVARNSFTIPSPPGIPEEVGTGKEHIIIQWTKPESDGGNEISNYLVD 22972

Query: 1301  -------RYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGR 1353
                    R++ V  +  V        D  + +T+L+ G +Y   V++V     S P    
Sbjct: 22973 KREKKSLRWTRVNKDYVV-------YDTRLKVTSLMEGCDYQFRVTAVNAAGNSEPSEAS 23025

Query: 1354  QKTGL-------DSPTGIDFSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPR 1402
                           P+     D T +S ++ W  P       I GY +    +      R
Sbjct: 23026 NFISCREPSYTPGPPSAPRVVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDTDQWYR 23085

Query: 1403  EDRVPHSRNS-ITLTNLTPGTEYVVSIVALN--GREESPLLIGQQSTVS--DVPRDLEVV 1457
                    RN+  T+ +L  G +Y   + A+N  G  E    I +   V   ++P DLE+ 
Sbjct: 23086 VHTNATIRNTEFTVPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEIP-DLELA 23144

Query: 1458  AATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTIT 1517
                  ++ I   A        R+    +G   PV  ++  G    A+ + +     Y++ 
Sbjct: 23145 DDLKKTVTIRAGAS------LRLMVSVSGRPPPVITWSKQGI-DLASRAIIDTTESYSLL 23197

Query: 1518  V-----------YAVTGRGDSPASSKPISIN-YRTEIDKPSQMQVTDVQDNSISVKW--- 1562
             +           Y +     S   S  + +  Y T    PS ++V +V  +S+++ W   
Sbjct: 23198 IVDKVNRYDAGKYTIEAENQSGKKSATVLVKVYDTPGPCPS-VKVKEVSRDSVTITWEIP 23256

Query: 1563  -LPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGES 1621
              +   +PV  Y +    +      KT T    +T   I GL     Y   V  +N  G  
Sbjct: 23257 TIDGGAPVNNY-IVEKREAAMRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYGIG 23315

Query: 1622  QPLVQTAVTNIDR----PKGLAFTDVDVDSIKIAWESP----QGQVSRY--RVTYSSPED 1671
             +P   +    +      P  L   DV   ++ +AWE P      +++ Y      +  E 
Sbjct: 23316 EPCETSDAVLVSEVPLVPAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGTER 23375

Query: 1672  GIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFT 1731
              +  +   P   E T  +  L  G +Y   + A ++   S+P    ++       DL+  
Sbjct: 23376 WMKVVTLKPTVLEHT--VTSLNEGEQYLFRIRAQNEKGVSEP---RETVTAVTVQDLR-- 23428

Query: 1732  QVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSG--------LM 1783
              V PT   +      + +   R    P E   P+      P ++S   +G        + 
Sbjct: 23429 -VLPTIDLSTMPQKTIHVPAGR----PVELVIPI--AGRPPPAASWFFAGSKLRESERVT 23481

Query: 1784  VATKYEVSVYALKDTLTSRPAQGVVTTLENVS-----------------PPRRARVTDAT 1826
             V T  +V+   +++T T R        L+NV+                 P    ++ +  
Sbjct: 23482 VETHTKVAKLTIRET-TIRDTGEYTLELKNVTGTTSETIKVIILDKPGPPTGPIKIDEID 23540

Query: 1827  ETTITISWRTKT----ETITGFQVDAVPAN--GQTPIQRTIKPDVRSYTITGLQPGTDYK 1880
              T+ITISW          ++G+ V+   A+  G  P+  ++     ++  T L  G +Y 
Sbjct: 23541 ATSITISWEPPELDGGAPLSGYVVEQRDAHRPGWLPVSESVTRS--TFKFTRLTEGNEYV 23598

Query: 1881  IYLYTLNDNARSSPV---VIDASTAI---DAPSNLRFLATTPNSLLVSWQPPR----ARI 1930
               +   N     S +   VI+  ++I     P  L+    + + + ++W PP     +++
Sbjct: 23599 FRVAATNRFGIGSYLQSEVIECRSSIRIPGPPETLQIFDVSRDGMTLTWYPPEDDGGSQV 23658

Query: 1931  TGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKK 1990
             TGYI++ ++  +     V +    +T    TGL  G EY   V A+      +P    K 
Sbjct: 23659 TGYIVERKEVRADRWVRVNKVPVTMTRYRSTGLTEGLEYEHRVTAINARGSGKPSRPSKP 23718

Query: 1991  TVQKTPFVTHPG 2002
              V   P +  PG
Sbjct: 23719 IVAMDP-IAPPG 23729



 Score = 88.2 bits (217), Expect = 9e-17
 Identities = 339/1547 (21%), Positives = 534/1547 (34%), Gaps = 251/1547 (16%)

Query: 628   IQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISI 684
             + W +P+    S I+ Y++  R  +    W   T      + T++GL  G  Y  ++ + 
Sbjct: 10330 LTWFSPEDDGGSPITNYVIEKRESDRRA-WTPVTYTVTRQNATVQGLIQGKAYFFRIAAE 10388

Query: 685   QQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSAS 744
                G        F  TS +  +        T P  P       V E+T ++  ++W    
Sbjct: 10389 NSIGMGP-----FVETSEALVIREPI----TVPERP---EDLEVKEVTKNTVTLTWNPPK 10436

Query: 745   DTVSGFRVEYELSEE--GDEPQYLDLPSTATS--VNIPDLLPGRKYIVNVYQISEDGEQS 800
                    + Y L     G E  +        S    +  L  G  Y   V  ++  G+  
Sbjct: 10437 YDGGSEIINYVLESRLIGTEKFHKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGK 10496

Query: 801   LILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPE 860
                 T   T  D    PT+       + +R     A    Y     P V     E ++ E
Sbjct: 10497 PSFCTKPITCKDELAPPTLHLDFRDKLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLE 10556

Query: 861   TANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQET---TGTPRSDTVPSPRD----L 913
               +  T     P       I A   +     VV++  T    G  + + V  P      +
Sbjct: 10557 --DDRTHIKTTPATLALEKIKAKRSDSGKYCVVVENSTGSRKGFCQVNVVDRPGPPVGPV 10614

Query: 914   QFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPGEHGQRLPI---SRNTFAEVTG 966
              F EVT   + I W PP     S +T Y ++   V         +P+   S  T  +V+ 
Sbjct: 10615 SFDEVTKDYMVISWKPPLDDGGSKITNYIIEKKEVG----KDVWMPVTSASAKTTCKVSK 10670

Query: 967   LSPGVTYYFKVFAVSHGRESKPLTAQQTTKLD------APTNLQFVNETDSTVLVRWTPP 1020
             L  G  Y F++ A +    S PL +      D      AP        T  + LV W  P
Sbjct: 10671 LLEGKDYIFRIHAENLYGISDPLVSDSMKAKDRFRVPDAPDQPIVTEVTKDSALVTWNKP 10730

Query: 1021  R---AQITGYRLTVGLTRRGQPRQYNVGP--SVSKYPLRNLQPASEYTVSLVA---IKGN 1072
                   IT Y L    T   +  +    P    +K+ + +L    +Y   + A   I   
Sbjct: 10731 HDGGKPITNYILEKRETMSKRWARVTKDPIHPYTKFRVPDLLEGCQYEFRVSAENEIGIG 10790

Query: 1073  QESPKATGVFTTLQPGSSIPPYNTEVTETT---IVITWTPAPR-------IGFKLGVRPS 1122
               SP +  VF         PP N E  +TT   + +TW P PR       +G+ +  +  
Sbjct: 10791 DPSPPSKPVFAKDPIAKPSPPVNPEAIDTTCNSVDLTWQP-PRHDGGSKILGYIVEYQ-K 10848

Query: 1123  QGGEAPREVTSDSGSIV-----VSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTP---L 1174
              G E  R       S       V+GL  G  Y + +  +    E D   V + V     L
Sbjct: 10849 VGDEEWRRANHTPESCPETKYKVTGLRDGQTYKFRVLAVNAAGESDPAHVPEPVLVKDRL 10908

Query: 1175  SPPTNLHLEANP---------DTGVLT----------VSWERSTTPDITGYRITTTPTNG 1215
              PP  L L+AN          DT  L+          V+W++      T  RI  TP   
Sbjct: 10909 EPP-ELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARIDVTPVGS 10967

Query: 1216  QQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRF 1275
             +    +    H D    +    +P     VSV  +  DK              PP DL  
Sbjct: 10968 KL--EIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDKPG------------PPRDLEV 11013

Query: 1276  TNIGPDTMRVTWAPPPSID---LTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGT 1332
             + I  D+  +TW  P       +TN++V    V + +  + LS +    +    +L  G 
Sbjct: 11014 SEIRKDSCYLTWKEPLDDGGSVITNYVVERRDVASAQ-WSPLSATSKKKSHFAKHLNEGN 11072

Query: 1333  EYVVSVSSVYEQHESTPLRGRQKT--GLDS------PTGIDFSDITANSFTVHWIAPR-- 1382
             +Y+  V++   Q+   P     K    LD       P  +   D+     ++ W  P   
Sbjct: 11073 QYLFRVAAE-NQYGRGPFVETPKPIKALDPLHPPGPPKDLHHVDVDKTEVSLVWNKPDRD 11131

Query: 1383  --ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN----GREE 1436
               + ITGY + +  E      +   V +      +T L  G  Y   + A N    G  +
Sbjct: 11132 GGSPITGYLVEYQEEGTQDWIKFKTVTNLE--CVVTGLQQGKTYRFRVKAENIVGLGLPD 11189

Query: 1437  SPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTV 1496
             + + I  Q  +  VP  +E+       L++       TVR+  I  G      P  ++T 
Sbjct: 11190 TTIPIECQEKL--VPPSVELDVKLIEGLVVK---AGTTVRFPAIIRGVP---VPTAKWTT 11241

Query: 1497  PGSK---------------STATISGL--KPGVDYTITVYAVTGRGDSPASSKPISINYR 1539
              GS+               S  TI     +   +Y ITV        + A SK ++++  
Sbjct: 11242 DGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEYQITV-------SNAAGSKTVAVHL- 11293

Query: 1540  TEIDKPSQ----MQVTDVQDNSISVKWLP----SSSPVTGYRVTT--TPKNGPGPTKTKT 1589
             T +D P      + + DV    +++ W P      SPV  Y V    T K+  G     +
Sbjct: 11294 TVLDVPGPPTGPINILDVTPEHMTISWQPPKDDGGSPVINYIVEKQDTRKDTWGVV---S 11350

Query: 1590  AGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDR------PKGLAFTDV 1643
             +G  +T++ I  LQ   EYV  V A+N  G   PL  T      +      P     TD+
Sbjct: 11351 SGSSKTKLKIPHLQKGCEYVFRVRAENKIGVGPPLDSTPTVAKHKFSPPSPPGKPVVTDI 11410

Query: 1644  DVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQ----GLRPGSEYT 1699
               ++  ++W  P+         Y      +   +   + +   A+L+    GL  G+ Y 
Sbjct: 11411 TENAATVSWTLPKSDGGSPITGYYMERREVTGKWVRVN-KTPIADLKFRVTGLYEGNTYE 11469

Query: 1700  VSVVALH------DDMESQPLIGTQSTAIPA-PTDLKFTQVTPTSLSAQWTPP----NVQ 1748
               V A +          S P+   +    P  P + K    +  +    WT P       
Sbjct: 11470 FRVFAENLAGLSKPSPSSDPIKACRPIKPPGPPINPKLKDKSRETADLVWTKPLSDGGSP 11529

Query: 1749  LTGYRVRVTPKEKTGPMKEINLAP--DSSSVVVSGLMVATKYEVSVYALKDTLTSRP--- 1803
             + GY V    K  T     IN        +  V GL+   +Y   + A        P   
Sbjct: 11530 ILGYVVE-CQKPGTAQWNRINKDELIRQCAFRVPGLIEGNEYRFRIKAANIVGEGEPREL 11588

Query: 1804  AQGVVTTLENVSPPR-------RARVTDATETTITISWRTK-------TETITG------ 1843
             A+ V+   + + PP        R  +T     TI I  R K       T T  G      
Sbjct: 11589 AESVIAK-DILHPPEVELDVTCRDVITVRVGQTIRILARVKGRPEPDITWTKEGKVLVRE 11647

Query: 1844  FQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAI 1903
              +VD +    +  +Q  IK  VR+           Y I     + +A+ S +V      +
Sbjct: 11648 KRVDLIQDLPRVELQ--IKEAVRA-------DHGKYIISAKNSSGHAQGSAIV----NVL 11694

Query: 1904  DAP---SNLRFLATTPNSLLVSWQPP----RARITGYIIKYEKPGSPPREVVPRPRPGVT 1956
             D P    NL+    T  +  +SW+ P     + IT +I++Y KP      +V      VT
Sbjct: 11695 DRPGPCQNLKVTNVTKENCTISWENPLDNGGSEITNFIVEYRKPNQKGWSIV---ASDVT 11751

Query: 1957  EATI-TGLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQKTPFVTHPG 2002
             +  I   L    EY   V A +N     P I  K  +     +  PG
Sbjct: 11752 KRLIKANLLANNEYYFRVCA-ENKVGVGPTIETKTPILAINPIDRPG 11797



 Score = 88.2 bits (217), Expect = 9e-17
 Identities = 260/1214 (21%), Positives = 438/1214 (36%), Gaps = 158/1214 (13%)

Query: 908   PSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPIS------RNTF 961
             P    L   EVT  K  + W PP     G ++D   V        RL  +      + T 
Sbjct: 15252 PPEGPLAVTEVTSEKCVLSWFPPLDD-GGAKIDHYIVQ--KRETSRLAWTNVASEVQVTK 15308

Query: 962   AEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKL------DAPTNLQFVNETDSTVLV 1015
              +VT L  G  Y F+V AV+     +PL ++    +      D P N +    T  +++V
Sbjct: 15309 LKVTKLLKGNEYIFRVMAVNKYGVGEPLESEPVLAVNPYGPPDPPKNPEVTTITKDSMVV 15368

Query: 1016  RWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVS-----KYPLRNLQPASEYTVSLVAIK 1070
              W  P +      +   + RR +  Q  +  +       +Y +  L    EY   ++A  
Sbjct: 15369 CWGHPDSDGGSEIINYIVERRDKAGQRWIKCNKKTLTDLRYKVSGLTEGHEYEFRIMAEN 15428

Query: 1071  -GNQESPKATGVF-----TTLQPGSSIPPYNTEVTET---TIVITWTP------APRIGF 1115
                  +P  T  F     T  +PG   PP N  V +T   +I I W        +   G+
Sbjct: 15429 AAGISAPSPTSPFYKACDTVFKPG---PPGNPRVLDTSRSSISIAWNKPIYDGGSEITGY 15485

Query: 1116  KLGVRPSQGGEAPREVTSDSG----SIVVSGLTPGVEYVYTIQVLRD---GQERDAPIVN 1168
              + +   +  E  + VT  +G    S  ++GLT   EY   I  +     G+    P   
Sbjct: 15486 MVEIALPEEDEW-QIVTPPAGLKATSYTITGLTENQEYKIRIYAMNSEGLGEPALVPGTP 15544

Query: 1169  KVVTPLSPP-TNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHA 1227
             K    + PP   L  +      +      R   P I G            G SL++    
Sbjct: 15545 KAEDRMLPPEIELDADLRKVVTIRACCTLRLFVP-IKGRPAPEVKWARDHGESLDKASIE 15603

Query: 1228  DQSSCTFDNLSPGLEYNVSVY--TVKDD--KESVPISDTIIPAVPPPTDLRFTNIGPDTM 1283
               SS T   +     ++   Y  TV++    +S  ++  ++    PP DL+   +   ++
Sbjct: 15604 STSSYTLLIVGNVNRFDSGKYILTVENSSGSKSAFVNVRVLDTPGPPQDLKVKEVTKTSV 15663

Query: 1284  RVTWAPPPSIDLTNFLVRYSPVKNE---EDVAELSISPSDNAVVLTNLLPGTEYVVSVSS 1340
              +TW  PP +D  + +  Y   K E   +  + ++ +    +  +  L  G  Y   V +
Sbjct: 15664 TLTW-DPPLLDGGSKIKNYIVEKRESTRKAYSTVATNCHKTSWKVDQLQEGCSYYFRVLA 15722

Query: 1341  VYEQHESTPLRGRQKTGLDS----PTGIDFSDITANSFTVHWIAPR----ATITGYRIRH 1392
               E     P    +          P  I   D+T NS ++ W  P     + I GY +  
Sbjct: 15723 ENEYGIGLPAETAESVKASERPLPPGKITLMDVTRNSVSLSWEKPEHDGGSRILGYIVEM 15782

Query: 1393  HPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPR 1452
               +          V       T+T L  G EY   + A N   E  +   +Q +V  + +
Sbjct: 15783 QTKGSDKWATCATV--KVTEATITGLIQGEEYSFRVSAQN---EKGISDPRQLSVPVIAK 15837

Query: 1453  DLEVVAA------TPTSLL---ISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTA 1503
             DL +  A      T T L    +  D P +      +T+ +   N P+++ T   ++ST 
Sbjct: 15838 DLVIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHK--DNVPLKQTTRVNAESTE 15895

Query: 1504  --TISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKP----SQMQVTDVQDNS 1557
               ++  +K      +  Y V     +  + + +++     +DKP      +++ +V  +S
Sbjct: 15896 NNSLLTIKDACREDVGHYVVKLTNSAGEAIETLNV---IVLDKPGPPTGPVKMDEVTADS 15952

Query: 1558  ISVKWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEG--LQPTVEYVVS 1611
             I++ W P      S +  Y V    K     T  +         TI+   L+   EY   
Sbjct: 15953 ITLSWGPPKYDGGSSINNYIV---EKRDTSTTTWQIVSATVARTTIKACRLKTGCEYQFR 16009

Query: 1612  VYAQNPSGE-----SQPLVQTAVTNIDRPKGLAFTDVDV-DSIKIAWESPQGQVSRYRVT 1665
             + A+N  G+     S+P V      +  P G     +   DS+++ W  P        + 
Sbjct: 16010 IAAENRYGKSTYLNSEPTVAQYPFKVPGPPGTPVVTLSSRDSMEVQWNEPISDGGSRVIG 16069

Query: 1666  YSSPEDGIHELF-------PAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQ 1718
             Y       + +        P P  +  T    GL  G EY   V A +     +P   ++
Sbjct: 16070 YHLERKERNSILWVKLNKTPIPQTKFKTT---GLEEGVEYEFRVSAENIVGIGKPSKVSE 16126

Query: 1719  STAIPAPTD----LKFTQVTPTSLSAQWTPPNV----QLTGYRVRVTPKEKTGPMKEINL 1770
                   P D     +   VT  S++ QW  P      ++TGY V      +   MK    
Sbjct: 16127 CYVARDPCDPPGRPEAIIVTRNSVTLQWKKPTYDGGSKITGYIVEKKELPEGRWMKASFT 16186

Query: 1771  APDSSSVVVSGLMVATKYEVSVYALKDT-LTSRPAQ--GVVTTLENVSPPRRARVTDATE 1827
                 +   V+GL+   +YE  V A     + S P++  G +T  + V PPR +      +
Sbjct: 16187 NIIDTHFEVTGLVEDHRYEFRVIARNAAGVFSEPSESTGAITARDEVDPPRISMDPKYKD 16246

Query: 1828  TTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQ-PGTDYKIYLYTL 1886
             T +  +  +       F+VDA       P  + IK D        L+   TD+   L ++
Sbjct: 16247 TIVVHAGES-------FKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSL-SV 16298

Query: 1887  NDNAR--SSPVVIDASTAIDAPS---NLRFL-------------ATTPNSLLVSWQPP-- 1926
              D  R  S   ++ A       S   N++ L               T     ++W+PP  
Sbjct: 16299 KDAVRVDSGNYILKAKNVAGERSVTVNVKVLDRPGPPEGPVVISGVTAEKCTLAWKPPLQ 16358

Query: 1927  --RARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEP 1984
                + I  YI++  +       VV           +T L  G EYT  ++A+      EP
Sbjct: 16359 DGGSDIINYIVERRETSRLVWTVVD-ANVQTLSCKVTKLLEGNEYTFRIMAVNKYGVGEP 16417

Query: 1985  LIGRKKTVQKTPFV 1998
             L   +  V K PFV
Sbjct: 16418 L-ESEPVVAKNPFV 16430



 Score = 86.3 bits (212), Expect = 3e-16
 Identities = 274/1330 (20%), Positives = 481/1330 (36%), Gaps = 177/1330 (13%)

Query: 812   DAPPDPT----VDQVDDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETAN 863
             D P  PT    +  + + S+ ++W  P+    + +T Y ++   +     TE++      
Sbjct: 20263 DRPGPPTGPVVISDITEESVTLKWEPPKYDGGSQVTNYILLKRETSTAVWTEVSATVART 20322

Query: 864   SVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFV-EVTDVK 922
              + +  L  G +Y   I A  EN+      I           T P P    +V  VT   
Sbjct: 20323 MMKVMKLTTGEEYQFRIKA--ENRFGISDHIDSACVTVKLPYTTPGPPSTPWVTNVTRES 20380

Query: 923   VTIMWTPPES----AVTGYRVDVIPVN-LPGEHGQRLPISRNTFAEVTGLSPGVTYYFKV 977
             +T+ W  P S    AV GY +++   N +  +   +L I R T  +VT +S G+ Y F+V
Sbjct: 20381 ITVGWHEPVSNGGSAVVGYHLEMKDRNSILWQKANKLVI-RTTHFKVTTISAGLIYEFRV 20439

Query: 978   FAVSHGRESKPL-TAQQTTKLDA---PTNLQFVNETDSTVLVRWTPPR----AQITGYRL 1029
             +A +     KP   ++    +DA   P N++  + + ++V + W  P     ++ITGY  
Sbjct: 20440 YAENAAGVGKPSHPSEPVLAIDACEPPRNVRITDISKNSVSLSWQQPAFDGGSKITGYI- 20498

Query: 1030  TVGLTRRGQP-----RQYNVGPSVSKYPLRNLQPASEYTVSLVA--IKGNQESP-KATGV 1081
                + RR  P     +      + +++ +  L   S+Y   + A    G+  +P +  G 
Sbjct: 20499 ---VERRDLPDGRWTKASFTNVTETQFIISGLTQNSQYEFRVFARNAVGSISNPSEVVGP 20555

Query: 1082  FTTLQ----PGSSIPPYNTEVTE----TTIV----ITWTPAPRI-GFKLGVRPSQGGEAP 1128
              T +     P   +P   TEV +    T++     I+  PAP I  +K            
Sbjct: 20556 ITCIDSYGGPVIDLPLEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVC 20615

Query: 1129  REVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDT 1188
              E T+D  SI++          Y +++        A I  +++    PP           
Sbjct: 20616 VENTTDLASILIKDADRLNSGCYELKLRNAMGSASATIRVQILDKPGPPGGPIEFKTVTA 20675

Query: 1189  GVLTVSWERSTTPD----ITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYN 1244
               +T+ W R    D    IT Y +    T+    + + E  H ++   T   +  G EY 
Sbjct: 20676 EKITLLW-RPPADDGGAKITHYIVEKRETSRVVWSMVSE--HLEECIITTTKIIKGNEYI 20732

Query: 1245  VSVYTVKDDKESVPI-SDTIIP-----AVPPPTDLRFTNIGPDTMRVTWAPP---PSIDL 1295
               V  V       P+ SD+++         PP     T I  ++M V W+ P      D+
Sbjct: 20733 FRVRAVNKYGIGEPLESDSVVAKNAFVTPGPPGIPEVTKITKNSMTVVWSRPIADGGSDI 20792

Query: 1296  TNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEY---VVSVSSVYEQHESTPLRG 1352
             + + +     K+      L  +  D    +T L   ++Y   V +V++  +   S P   
Sbjct: 20793 SGYFLEKRDKKSLGWFKVLKETIRDTRQKVTGLTENSDYQYRVCAVNAAGQGPFSEPSEF 20852

Query: 1353  RQKTGLDSPTG----IDFSDITANSFTVHWIAP----RATITGYRIRHHPEHFSGRPRED 1404
              +      P G    I  +D T +S T+ W  P     + +TGY +    E   G   E 
Sbjct: 20853 YKAADPIDPPGPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVV----EIRQGEEEEW 20908

Query: 1405  RVPHSRNSITLT-----NLTPGTEYVVSIVALN-GREESPLLIGQQSTVSDVPR----DL 1454
                 ++  +  T     NL PG  Y   + A+N   +  P+ + +     D+      DL
Sbjct: 20909 TTVSTKGEVRTTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQAKDILEAPEIDL 20968

Query: 1455  EVVAATPTSLLISWDA-----------PAVTVRYYRITYGETGGNSPVQEFTVPGSKSTA 1503
             +V   T        D            P VT R      G     S         S S  
Sbjct: 20969 DVALRTSVIAKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYS----IENTDSSSLL 21024

Query: 1504  TISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPS---QMQVTDVQDNSISV 1560
             TI  +         +    G G+  +S+  + +     +D P+   ++QV  V   ++++
Sbjct: 21025 TIPQVTRNDTGKYILTIENGVGEPKSSTVSVKV-----LDTPAACQKLQVKHVSRGTVTL 21079

Query: 1561  KWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGP-DQTEMTIEGLQPTVEYVVSVYAQ 1615
              W P      SP+  Y +    ++    T +  +     T   +  L     +   V A+
Sbjct: 21080 LWDPPLIDGGSPIINYVI--EKRDATKRTWSVVSHKCSSTSFKLIDLSEKTPFFFRVLAE 21137

Query: 1616  NPSGESQPLVQT---AVTNIDRP-KGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPED 1671
             N  G  +P   T       +  P + L+  D    S+ ++W  P          Y     
Sbjct: 21138 NEIGIGEPCETTEPVKAAEVPAPIRDLSMKDSTKTSVILSWTKPDFDGGSVITEYVVERK 21197

Query: 1672  GIHELFPAPDGEEDTAELQ--GLRPGSEYTVSVVALHDDMESQPL-IGTQSTAIPAPTDL 1728
             G  E   +  G   T E++   L+  S     V A ++   S P+ IG        P  +
Sbjct: 21198 GKGEQTWSHAGISKTCEIEVSQLKEQSVLEFRVFAKNEKGLSDPVTIG--------PITV 21249

Query: 1729  KFTQVTP-TSLSAQWTPPNVQLT---GYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMV 1784
             K   +TP   LS     P  Q+T   G+ V +    K  P   I+   D   +  S  + 
Sbjct: 21250 KELIITPEVDLS---DIPGAQVTVRIGHNVHLELPYKGKPKPSISWLKDGLPLKESEFVR 21306

Query: 1785  ATKYEVSV-YALKDTLTSRPAQ------------GVVTTLENVSPPRR----ARVTDATE 1827
              +K E  +  ++K+       +             V  T+  + PP +     R  +   
Sbjct: 21307 FSKTENKITLSIKNAKKEHGGKYTVILDNAVCRIAVPITVITLGPPSKPKGPIRFDEIKA 21366

Query: 1828  TTITISWRTKTET----ITGFQVDAVPANGQTPIQRTIKPDVR-SYTITGLQPGTDYKIY 1882
              ++ +SW    +     IT + ++      QT  +       R ++ +  L    +Y+  
Sbjct: 21367 DSVILSWDVPEDNGGGEITCYSIEK-RETSQTNWKMVCSSVARTTFKVPNLVKDAEYQFR 21425

Query: 1883  LYTLNDNARSSPVVIDASTA------IDAPSNLRFLATTPNSLLVSWQPP----RARITG 1932
             +   N    S P+V     A         P        T + + ++W  P     + +TG
Sbjct: 21426 VRAENRYGVSQPLVSSIIVAKHQFRIPGPPGKPVIYNVTSDGMSLTWDAPVYDGGSEVTG 21485

Query: 1933  YIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTV 1992
             + ++ ++  S   + V        E   TGL  G +Y   V A  +   S P    K T+
Sbjct: 21486 FHVEKKERNSILWQKVNTSPISGREYRATGLVEGLDYQFRVYAENSAGLSSPSDPSKFTL 21545

Query: 1993  QKTPFVTHPG 2002
               +P V  PG
Sbjct: 21546 AVSP-VDPPG 21554



 Score = 84.3 bits (207), Expect = 1e-15
 Identities = 337/1686 (19%), Positives = 592/1686 (35%), Gaps = 300/1686 (17%)

Query: 628   IQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISI 684
             + W+ P+    S I+ +I+  R    +  W++  I    +   I GL  G  Y+ ++I+ 
Sbjct: 8910  LNWSDPEDDGGSEITGFIIE-RKDAKMHTWRQP-IETERSKCDITGLLEGQEYKFRVIAK 8967

Query: 685   QQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWV--- 741
              ++G                PV    +        P      + TE T S+  + W    
Sbjct: 8968  NKFG-------------CGPPVEIGPILAVDPLGPPTSPERLTYTERTKSTITLDWKEPR 9014

Query: 742   -SASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQS 800
              +    + G+ +E    ++ D  +        TS  + +L   + Y   V  ++E GE  
Sbjct: 9015  SNGGSPIQGYIIEKRRHDKPDFERVNKRLCPTTSFLVENLDEHQMYEFRVKAVNEIGESE 9074

Query: 801   LILSTSQTTAPDAPPDPTVD---QVDDTSIVVRWSRP---QAPITGYRIVYSPSVEGSST 854
               L  +     D  P PT+     V   +I V+   P    A +TG  +   P +E S  
Sbjct: 9075  PSLPLNVVIQDDEVP-PTIKLRLSVRGDTIKVKAGEPVHIPADVTGLPM---PKIEWSKN 9130

Query: 855   E--LNLPETANSVTLSDLQPG-VQYNITI-YAVEENQESTPVVIQQETTGTPRS------ 904
             E  +  P  A  +T  ++     +  ++I  AV E++ +  V          R+      
Sbjct: 9131  ETVIEKPTDALQITKEEVSRSEAKTELSIPKAVREDKGTYTVTASNRLGSVFRNVHVEVY 9190

Query: 905   DTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPGEHGQRLPISRNT 960
             D    PR+L   ++      + W  P     S +T Y +D    +      + +    NT
Sbjct: 9191  DRPSPPRNLAVTDIKAESCYLTWDAPLDNGGSEITHYVIDKRDASRKKAEWEEVT---NT 9247

Query: 961   FAE----VTGLSPGVTYYFKV-----FAVSHGRESKPLTAQQTTKLDAPTNL-QFVNETD 1010
               E    +  L P   Y F+V     + +S   +S  +  Q   +L  P    + +  T 
Sbjct: 9248  AVEKRYGIWKLIPNGQYEFRVRAVNKYGISDECKSDKVVIQDPYRLPGPPGKPKVLARTK 9307

Query: 1011  STVLVRWTPP----RAQITGYRLTVGLTRRGQPRQY----------NVGPSVSKYPLRNL 1056
              ++LV WTPP     + ITGY     L +R +   Y           VG    ++ +  L
Sbjct: 9308  GSMLVSWTPPLDNGGSPITGY----WLEKREEGSPYWSRVSRAPITKVGLKGVEFNVPRL 9363

Query: 1057  QPASEYTVSLVAIKG------NQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPA 1110
                 +Y    +AI        ++ S           PG    P   + T+++I + W P 
Sbjct: 9364  LEGVKYQFRAMAINAAGIGPPSEPSDPEVAGDPIFPPGPPSCPEVKDKTKSSISLGWKPP 9423

Query: 1111  PRIGFKLGVRPSQG--GEAPREVTSD------------SGSIVVSGLTPGVEYVYTIQVL 1156
                  K G  P +G   E   E T+D            +   VV  L    +Y + ++ +
Sbjct: 9424  A----KDGGSPIKGYIVEMQEEGTTDWKRVNEPDKLITTCECVVPNLKELRKYRFRVKAV 9479

Query: 1157  RD-GQERDAPIVNKV-VTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPT- 1213
              + G+   +    ++  T +     + ++      ++  +  +   P +   R T   + 
Sbjct: 9480  NEAGESEPSDTTGEIPATDIQEEPEVFIDIGAQDCLVCKAGSQIRIPAVIKGRPTPKSSW 9539

Query: 1214  --NGQQGNSLEEVVH---ADQSSCTFDNLSPGL----------EYNVSVYTVKDDKESVP 1258
               +G+   ++++ VH    D    T +N S  +          +Y+++    K  +++  
Sbjct: 9540  EFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECKRSHTGKYSITAKN-KAGQKTAN 9598

Query: 1259  ISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEED-VAELSIS 1317
                 ++    PP DL+ ++I   + R++W  P   D  + +  Y   K   D  A   ++
Sbjct: 9599  CRVKVMDVPGPPKDLKVSDITRGSCRLSWKMPDD-DGGDRIKGYVIEKRTIDGKAWTKVN 9657

Query: 1318  P--SDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGL-------DSPTGIDFSD 1368
             P       V+ +LL   +Y   V +        P+   Q+T         D P  +    
Sbjct: 9658  PDCGSTTFVVPDLLSEQQYFFRVRAENRFGIGPPVETIQRTTARDPIYPPDPPIKLKIGL 9717

Query: 1369  ITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPRED-RVPHSRN----SITLTNLT 1419
             IT N+  + W  P+    + +T Y +       +G  +E  R  + R+      T+ +L 
Sbjct: 9718  ITKNTVHLSWKPPKNDGGSPVTHYIVECLAWDPTGTKKEAWRQCNKRDVEELQFTVEDLV 9777

Query: 1420  PGTEYVVSIVALN--GREESPLLIG-------QQSTVSDVPRDLEVVAATPTSLLIS-WD 1469
              G EY   + A+N  G  +    +G             D+   +EV   T  +++     
Sbjct: 9778  EGGEYEFRVKAVNAAGVSKPSATVGPCDCQRPDMPPSIDLKEFMEVEEGTNVNIVAKIKG 9837

Query: 1470  APAVTVRYYRITYGETGGNSPVQEFT-----VPGSKSTATISGLKPGVDYTITVYAVTGR 1524
              P  T+ +++    +     PV   T     V     T  I   +       T+ AV   
Sbjct: 9838  VPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDTGLYTITAVNNL 9897

Query: 1525  GDSPASSKPISINYRTEIDKP-SQMQVTDVQDNSISVKWLP----SSSPVTGYRVTTTPK 1579
             G    +SK + +N       P   ++   V  + +++ W P      S +T Y +     
Sbjct: 9898  G---TASKEMRLNVLGRPGPPVGPIKFESVSADQMTLSWFPPKDDGGSKITNYVIEKREA 9954

Query: 1580  NGPGPTKT---KTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVT--NI-- 1632
             N     KT    ++ P +   TI  L    EYV  + AQN  G  +PL     T  N+  
Sbjct: 9955  N----RKTWVHVSSEPKECTYTIPKLLEGHEYVFRIMAQNKYGIGEPLDSEPETARNLFS 10010

Query: 1633  --DRPKGLAFTDVDVDSIKIAWESPQ----GQVSRYRVTYSSPEDGIHELFPAPDGEEDT 1686
                 P     + V  +S+ + WE P+      V+ Y   +   +D   + +   + +   
Sbjct: 10011 VPGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPVTGY---WLEMKDTTSKRWKRVNRDPIK 10067

Query: 1687  A-------ELQGLRPGSEYTVSVVALH------DDMESQPLIGTQSTAIPAPTDLKFTQV 1733
             A       ++ GL  GS+Y   V A++        + S P       A P P   K T  
Sbjct: 10068 AMTLGVSYKVTGLIEGSDYQFRVYAINAAGVGPASLPSDPATARDPIAPPGPPFPKVTDW 10127

Query: 1734  TPTSLSAQWTPP----NVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYE 1789
             T +S   +W+PP      ++TGY V    + K    K  +     + +VV+GL     Y+
Sbjct: 10128 TKSSADLEWSPPLKDGGSKVTGYIVEYKEEGKEEWEKGKDKEVRGTKLVVTGLKEGAFYK 10187

Query: 1790  VSVYALKDTLTSRPAQGVVTTLEN----VSPPRR--ARVTD----------------ATE 1827
               V A+       P + V   +E     VSP  +  A V D                + +
Sbjct: 10188 FRVRAVNIAGIGEPGE-VTDVIEMKDRLVSPDLQLDASVRDRIVVHAGGVIRIIAYVSGK 10246

Query: 1828  TTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDV--RSYTITGLQPGTDYKIYLYT 1885
                T++W     T+              P + TI+      S  I   Q        L  
Sbjct: 10247 PPPTVTWNMNERTL--------------PQEATIETTAISSSMVIKNCQRSHQGVYSLLA 10292

Query: 1886  LNDNARSSPVVIDASTAIDAPSNLRFLA--TTPNSLLVSWQPPR----ARITGYIIKYEK 1939
              N+       +I     +  P    FLA   T  S  ++W  P     + IT Y+I  EK
Sbjct: 10293 KNEAGERKKTIIVDVLDVPGPVGTPFLAHNLTNESCKLTWFSPEDDGGSPITNYVI--EK 10350

Query: 1940  PGSPPREVVPRPRPGVTE-ATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQKTPFV 1998
               S  R   P       + AT+ GL  G  Y   + A             + ++   PFV
Sbjct: 10351 RESDRRAWTPVTYTVTRQNATVQGLIQGKAYFFRIAA-------------ENSIGMGPFV 10397

Query: 1999  THPGYDTGNGIQLPGTSGQQPSVGQQMIFEEHGFRRTTPPTTATPIRHRPRPYPPNVGQE 2058
                                     + ++  E             PI    RP    V + 
Sbjct: 10398 ---------------------ETSEALVIRE-------------PITVPERPEDLEVKEV 10423

Query: 2059  ALSQTTISWAP--FQDTSE---YIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYN 2113
               +  T++W P  +   SE   Y++    +GT++          S   T+ GL  G TY 
Sbjct: 10424 TKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEKFHKVTNDNLLSRKYTVKGLKEGDTYE 10483

Query: 2114  IIVEAL 2119
               V A+
Sbjct: 10484 YRVSAV 10489



 Score = 84.3 bits (207), Expect = 1e-15
 Identities = 134/644 (20%), Positives = 244/644 (37%), Gaps = 79/644 (12%)

Query: 1421  GTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAP----AVTVR 1476
             G +Y++    + G +  P+ +            ++V   T     ++W  P       + 
Sbjct: 17388 GGQYILRASNVAGSKSFPVNVKVLDRPGPPEGPVQVTGVTSEKCSLTWSPPLQDGGSDIS 17447

Query: 1477  YYRITYGETGGNSPVQEFTVPGSK---STATISGLKPGVDYTITVYAVTGRG-DSPASSK 1532
             +Y +   ET   +    +TV  S+   ++  ++ L  G +Y   + AV   G   P  S 
Sbjct: 17448 HYVVEKRETSRLA----WTVVASEVVTNSLKVTKLLEGNEYVFRIMAVNKYGVGEPLESA 17503

Query: 1533  PISINYRTEID-KPSQMQVTDVQDNSISVKW-LPSS---SPVTGYRVTTTPKNGPGPTKT 1587
             P+ +     +   P  ++VT++  +S++V W  P S   S + GY V    ++G    K 
Sbjct: 17504 PVLMKNPFVLPGPPKSLEVTNIAKDSMTVCWNRPDSDGGSEIIGYIVEKRDRSGIRWIKC 17563

Query: 1588  KTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTA-------VTNIDRPKGLAF 1640
                      + + GL    EY   V A+N +G  +P   T        V     P     
Sbjct: 17564 NKRRITDLRLRVTGLTEDHEYEFRVSAENAAGVGEPSPATVYYKACDPVFKPGPPTNAHI 17623

Query: 1641  TDVDVDSIKIAWESP----QGQVSRYRVTYSSPEDGIHELFPAPDGEEDTA-ELQGLRPG 1695
              D   +SI +AW  P      ++  Y V     ++   ++     G   T  E+  L   
Sbjct: 17624 VDTTKNSITLAWGKPIYDGGSEILGYVVEICKADEEEWQIVTPQTGLRVTRFEISKLTEH 17683

Query: 1696  SEYTVSVVALHDDMESQPLIGT-QSTAIPAPTDLKFTQVTPT-SLSAQWTPPNVQLTGYR 1753
              EY + V AL+        +G  ++T++P     +     P   L ++     V   G  
Sbjct: 17684 QEYKIRVCALNK-------VGLGEATSVPGTVKPEDKLEAPELDLDSELRKGIVVRAGGS 17736

Query: 1754  VRVTPKEKTGPMKEINLAPD----SSSVVVSGLMVATKYEVS----------VYALKDTL 1799
              R+    K  P  EI  + +    +  V +   +  T+  +           +  L+++ 
Sbjct: 17737 ARIHIPFKGRPTPEITWSREEGEFTDKVQIEKGVNYTQLSIDNCDRNDAGKYILKLENSS 17796

Query: 1800  TSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKT----ETITGFQVDAVPANGQT 1855
              S+ A   V  L+   PP+   V +  + +  + W          +  + +D   +  + 
Sbjct: 17797 GSKSAFVTVKVLDTPGPPQNLAVKEVRKDSAFLVWEPPIIDGGAKVKNYVIDKRESTRKA 17856

Query: 1856  PIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPV-VIDASTAIDAPS-----NL 1909
                 + K    S+ +  L  G  Y   +   N+     PV  +DA  A + PS      L
Sbjct: 17857 YANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFGVGVPVETVDAVKAAEPPSPPGKVTL 17916

Query: 1910  RFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEP 1965
               ++ T  SL+  W+ P     +R+ GY+++ +  G+    +V   +  V  A +TGL  
Sbjct: 17917 TDVSQTSASLM--WEKPEHDGGSRVLGYVVEMQPKGTEKWSIVAESK--VCNAVVTGLSS 17972

Query: 1966  GTEYTIYVIALKNNQKSE------PLIGRKKTVQ---KTPFVTH 2000
             G EY   V A     KS+      P+I +  T+Q   K PF T+
Sbjct: 17973 GQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKLPFNTY 18016



 Score = 82.4 bits (202), Expect = 5e-15
 Identities = 130/589 (22%), Positives = 217/589 (36%), Gaps = 70/589 (11%)

Query: 1505  ISGLKPGVDYTITVYAVTGRG-DSPASSKPI-SINYRTEIDKPSQMQVTDVQDNSISVKW 1562
             ++ L  G +YT  + AV   G   P  S+P+ + N     D P   +VT V  +S+ V W
Sbjct: 16393 VTKLLEGNEYTFRIMAVNKYGVGEPLESEPVVAKNPFVVPDAPKAPEVTTVTKDSMIVVW 16452

Query: 1563  -LPSS---SPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPS 1618
               P+S   S + GY +    K G   T+       +  + + GL    +Y   V A+N +
Sbjct: 16453 ERPASDGGSEILGYVLEKRDKEGIRWTRCHKRLIGELRLRVTGLIENHDYEFRVSAENAA 16512

Query: 1619  GESQPLVQTA-------VTNIDRPKGLAFTDVDVDSIKIAWESP----QGQVSRYRVTYS 1667
             G S+P   +A       +     P      D+   S+ ++W  P      ++  Y V   
Sbjct: 16513 GLSEPSPPSAYQKACDPIYKPGPPNNPKVIDITRSSVFLSWSKPIYDGGCEIQGYIVEKC 16572

Query: 1668  SPEDGIHELFPAPDGEEDT-AELQGLRPGSEYTVSVVAL-------HDDMESQPLIGTQS 1719
                 G   +   P G   T  E++ L    EY   + A+       H D+    ++  + 
Sbjct: 16573 DVSVGEWTMCTPPTGINKTNIEVEKLLEKHEYNFRICAINKAGVGEHADVPGPIIVEEKL 16632

Query: 1720  TAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEK----TGPMKEINLAPDSS 1775
              A     DL+  ++                   + R TP+ K     G +++  +   +S
Sbjct: 16633 EAPDIDLDLELRKIINIRAGGSLR----LFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTS 16688

Query: 1776  SVVVSGLMVATKYEVSVY--ALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITIS 1833
             S     L    +Y+   Y   L+++  ++ A   V  L+  SPP   +VT+ T+ +++I+
Sbjct: 16689 SFTSLVLDNVNRYDSGKYTLTLENSSGTKSAFVTVRVLDTPSPPVNLKVTEITKDSVSIT 16748

Query: 1834  WRTKT----ETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDN 1889
             W          I  + V+   A  ++           S+ I  LQ G  Y   +   N+ 
Sbjct: 16749 WEPPLLDGGSKIKNYIVEKREATRKSYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAENEY 16808

Query: 1890  ARSSPV----VIDASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPG 1941
                 P      I  +     P  +     T NS+ +SW  P     ++I  YI++ +   
Sbjct: 16809 GIGLPAQTADPIKVAEVPQPPGKITVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKH 16868

Query: 1942  SPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQKTPFVTHP 2001
             S       R +    +A IT L  G EY   V+A+    +S+P       V K   V  P
Sbjct: 16869 SEKWSECARVKS--LQAVITNLTQGEEYLFRVVAVNEKGRSDPRSLAVPIVAK-DLVIEP 16925

Query: 2002  GYDTGNGIQLPGTSGQQPSVGQQMIFEEHGFRRTTPPTTATPIRHRPRP 2050
                       P  S     VGQ +  E              PI  RP+P
Sbjct: 16926 DVK-------PAFSSYSVQVGQDLKIE-------------VPISGRPKP 16954



 Score = 82.0 bits (201), Expect = 6e-15
 Identities = 266/1310 (20%), Positives = 442/1310 (33%), Gaps = 219/1310 (16%)

Query: 731   ITASSFVVSWVSASDTVSGFRVEYELSE-EGDEPQYLDLPSTAT--SVNIPDLLPGRKYI 787
             ++A    +SW    D        Y + + E +   ++ + S     +  IP LL G +Y+
Sbjct: 9924  VSADQMTLSWFPPKDDGGSKITNYVIEKREANRKTWVHVSSEPKECTYTIPKLLEGHEYV 9983

Query: 788   V-----NVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ----API 838
                   N Y I E  +     + +  + P AP  PTV  V   S+ V W  P+    +P+
Sbjct: 9984  FRIMAQNKYGIGEPLDSEPETARNLFSVPGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPV 10043

Query: 839   TGYRIVYSPSVEGSSTELNLPETANSVTL------SDLQPGVQYNITIYAVEENQESTPV 892
             TGY +    +       +N  +   ++TL      + L  G  Y   +YA+       P 
Sbjct: 10044 TGYWLEMKDTTSKRWKRVN-RDPIKAMTLGVSYKVTGLIEGSDYQFRVYAINAAGVG-PA 10101

Query: 893   VIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPG 948
              +  +          P P   +  + T     + W+PP     S VTGY V+        
Sbjct: 10102 SLPSDPATARDPIAPPGPPFPKVTDWTKSSADLEWSPPLKDGGSKVTGYIVEYKEEGKEE 10161

Query: 949   EHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGR-----------ESKPLTAQQTTKL 997
                 +    R T   VTGL  G  Y F+V AV+              E K        +L
Sbjct: 10162 WEKGKDKEVRGTKLVVTGLKEGAFYKFRVRAVNIAGIGEPGEVTDVIEMKDRLVSPDLQL 10221

Query: 998   DAPTNLQFVNETDSTV----LVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSV--SKY 1051
             DA    + V      +     V   PP        +T  +  R  P++  +  +   S  
Sbjct: 10222 DASVRDRIVVHAGGVIRIIAYVSGKPPPT------VTWNMNERTLPQEATIETTAISSSM 10275

Query: 1052  PLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNT-EVTETTIVITWTP- 1109
              ++N Q + +   SL+A     E  K   V     PG    P+    +T  +  +TW   
Sbjct: 10276 VIKNCQRSHQGVYSLLAKNEAGERKKTIIVDVLDVPGPVGTPFLAHNLTNESCKLTWFSP 10335

Query: 1110  -----APRIGFKLGVRPS-QGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRD----- 1158
                  +P   + +  R S +    P   T    +  V GL  G  Y + I          
Sbjct: 10336 EDDGGSPITNYVIEKRESDRRAWTPVTYTVTRQNATVQGLIQGKAYFFRIAAENSIGMGP 10395

Query: 1159  -GQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSW---ERSTTPDITGYRITTTPTN 1214
               +  +A ++ + +T    P +L ++       +T++W   +     +I  Y + +    
Sbjct: 10396 FVETSEALVIREPITVPERPEDLEVK-EVTKNTVTLTWNPPKYDGGSEIINYVLESRLIG 10454

Query: 1215  GQQGNSLEEVVHADQSSCTFDNLSPG--LEYNVSVYTV----KDDKESVPISDTIIPAVP 1268
              ++ + +    +      T   L  G   EY VS   +    K    + PI  T    + 
Sbjct: 10455 TEKFHKVTN-DNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGKPSFCTKPI--TCKDELA 10511

Query: 1269  PPT---------DLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAE---LSI 1316
             PPT          +R       T R +  P P +         S  K+E DV E     I
Sbjct: 10512 PPTLHLDFRDKLTIRVGEAFALTGRYSGKPKPKV---------SWFKDEADVLEDDRTHI 10562

Query: 1317  SPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSP----TGIDFSDITAN 1372
               +   + L  +            V E    +     Q   +D P      + F ++T +
Sbjct: 10563 KTTPATLALEKIKAKRSDSGKYCVVVENSTGSRKGFCQVNVVDRPGPPVGPVSFDEVTKD 10622

Query: 1373  SFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVP----HSRNSITLTNLTPGTEYVVSI 1428
                + W  P     G +I ++        ++  +P     ++ +  ++ L  G +Y+  I
Sbjct: 10623 YMVISW-KPPLDDGGSKITNYIIEKKEVGKDVWMPVTSASAKTTCKVSKLLEGKDYIFRI 10681

Query: 1429  VALNGREESPLLIG------QQSTVSDVPRDLEVVAATPTSLLISWDAP----------- 1471
              A N    S  L+        +  V D P    V   T  S L++W+ P           
Sbjct: 10682 HAENLYGISDPLVSDSMKAKDRFRVPDAPDQPIVTEVTKDSALVTWNKPHDGGKPITNYI 10741

Query: 1472  -----AVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVT--GR 1524
                   ++ R+ R+T        P  +F VP          L  G  Y   V A    G 
Sbjct: 10742 LEKRETMSKRWARVTKDPI---HPYTKFRVP---------DLLEGCQYEFRVSAENEIGI 10789

Query: 1525  GDSPASSKPISINYRTEIDKPS---QMQVTDVQDNSISVKWLP----SSSPVTGYRVTTT 1577
             GD    SKP+    +  I KPS     +  D   NS+ + W P      S + GY +   
Sbjct: 10790 GDPSPPSKPVFA--KDPIAKPSPPVNPEAIDTTCNSVDLTWQPPRHDGGSKILGY-IVEY 10846

Query: 1578  PKNGPGPTKTKTAGPD---QTEMTIEGLQPTVEYVVSVYAQNPSGESQP-------LVQT 1627
              K G    +     P+   +T+  + GL+    Y   V A N +GES P       LV+ 
Sbjct: 10847 QKVGDEEWRRANHTPESCPETKYKVTGLRDGQTYKFRVLAVNAAGESDPAHVPEPVLVKD 10906

Query: 1628  AV--------TNIDRPKGLAFTDV--------DVDSIKIAWESPQGQVSRYRVTYSSPED 1671
              +         N+ R + +   D          V   K+ W+              +P  
Sbjct: 10907 RLEPPELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARIDVTPVG 10966

Query: 1672  GIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFT 1731
                E+  A   +     L    P    TVSV  L  D                P DL+ +
Sbjct: 10967 SKLEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDKPG------------PPRDLEVS 11014

Query: 1732  QVTPTSLSAQWTPP----NVQLTGYRVR-------------VTPKEKTGPMKEINLAPDS 1774
             ++   S    W  P       +T Y V               T K+K+   K +N     
Sbjct: 11015 EIRKDSCYLTWKEPLDDGGSVITNYVVERRDVASAQWSPLSATSKKKSHFAKHLN----E 11070

Query: 1775  SSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISW 1834
              +  +  +    +Y    +      T +P +  +  L    PP+     D  +T +++ W
Sbjct: 11071 GNQYLFRVAAENQYGRGPF----VETPKPIK-ALDPLHPPGPPKDLHHVDVDKTEVSLVW 11125

Query: 1835  ----RTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYK 1880
                 R     ITG+ V+      Q  I+     ++    +TGLQ G  Y+
Sbjct: 11126 NKPDRDGGSPITGYLVEYQEEGTQDWIKFKTVTNLEC-VVTGLQQGKTYR 11174



 Score = 80.9 bits (198), Expect = 1e-14
 Identities = 248/1194 (20%), Positives = 435/1194 (36%), Gaps = 142/1194 (11%)

Query: 908   PSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAE 963
             P    +Q   VT  K ++ W+PP     S ++ Y V+    +          +  N+  +
Sbjct: 17416 PPEGPVQVTGVTSEKCSLTWSPPLQDGGSDISHYVVEKRETSRLAWTVVASEVVTNSL-K 17474

Query: 964   VTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDA------PTNLQFVNETDSTVLVRW 1017
             VT L  G  Y F++ AV+     +PL +      +       P +L+  N    ++ V W
Sbjct: 17475 VTKLLEGNEYVFRIMAVNKYGVGEPLESAPVLMKNPFVLPGPPKSLEVTNIAKDSMTVCW 17534

Query: 1018  TPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQ---------PASEYTVSLVA 1068
               P +   G    +G     + R        +K  + +L+            E+ VS   
Sbjct: 17535 NRPDSD--GGSEIIGYIVEKRDRSGIRWIKCNKRRITDLRLRVTGLTEDHEYEFRVSAEN 17592

Query: 1069  IKGNQESPKATGVFTTLQPGSSI-PPYNTEVTETT---IVITWTP------APRIGFKLG 1118
               G  E   AT  +    P     PP N  + +TT   I + W        +  +G+ + 
Sbjct: 17593 AAGVGEPSPATVYYKACDPVFKPGPPTNAHIVDTTKNSITLAWGKPIYDGGSEILGYVVE 17652

Query: 1119  VRPSQGGEAPREVTSDSGSIV----VSGLTPGVEYVYTIQVLRD---GQERDAPIVNKVV 1171
             +  +   E  + VT  +G  V    +S LT   EY   +  L     G+    P   K  
Sbjct: 17653 ICKADEEEW-QIVTPQTGLRVTRFEISKLTEHQEYKIRVCALNKVGLGEATSVPGTVKPE 17711

Query: 1172  TPLSPPTNLHLEANPDTGVLT---------VSWERSTTPDITGYRITTTPTNGQQGNSLE 1222
               L  P  L L++    G++          + ++   TP+IT  R     T+  Q   +E
Sbjct: 17712 DKLEAP-ELDLDSELRKGIVVRAGGSARIHIPFKGRPTPEITWSREEGEFTDKVQ---IE 17767

Query: 1223  EVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRFTNIGPDT 1282
             + V+  Q S    + +   +Y + +      K +  ++  ++    PP +L    +  D+
Sbjct: 17768 KGVNYTQLSIDNCDRNDAGKYILKLENSSGSKSAF-VTVKVLDTPGPPQNLAVKEVRKDS 17826

Query: 1283  MRVTWAPPPSIDLTNFLVRYSPVKNEED---VAELSISPSDNAVVLTNLLPGTEYVVSVS 1339
               + W PP  ID    +  Y   K E      A +S   S  +  + NL  G  Y   V 
Sbjct: 17827 AFLVWEPP-IIDGGAKVKNYVIDKRESTRKAYANVSSKCSKTSFKVENLTEGAIYYFRVM 17885

Query: 1340  SVYEQHESTPLR---GRQKTGLDSPTG-IDFSDITANSFTVHWIAPR----ATITGYRIR 1391
             +  E     P+      +     SP G +  +D++  S ++ W  P     + + GY + 
Sbjct: 17886 AENEFGVGVPVETVDAVKAAEPPSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVE 17945

Query: 1392  HHPEHFSGRPREDRVPHSRN-SITLTNLTPGTEYVVSIVALNGREES-PLLIGQQSTVSD 1449
               P+   G  +   V  S+  +  +T L+ G EY   + A N + +S P ++G      D
Sbjct: 17946 MQPK---GTEKWSIVAESKVCNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKD 18002

Query: 1450  VPRDLEVVAATPTSLL-----ISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTAT 1504
             +     +     T  +     +  + P +      I++ + G   P+++ T    + TAT
Sbjct: 18003 LTIQPSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDG--EPLKQTTRVNVEETAT 18060

Query: 1505  --ISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKP-SQMQVTDVQDNSISVK 1561
               +  +K G       Y VT    +  +++ +S+    +   P   ++  +V  + + + 
Sbjct: 18061 STVLHIKEGNKDDFGKYTVTATNSAGTATENLSVIVLEKPGPPVGPVRFDEVSADFVVIS 18120

Query: 1562  WLPSS----SPVTGYRV-----TTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSV 1612
             W P +      ++ Y V     TTT  +    T  +T       + I  L+   EY   +
Sbjct: 18121 WEPPAYTGGCQISNYIVEKRDTTTTTWHMVSATVARTT------IKITKLKTGTEYQFRI 18174

Query: 1613  YAQNPSGESQPLVQTAVT-----NIDRPKGLAF-TDVDVDSIKIAWESPQGQVSRYRVTY 1666
             +A+N  G+S PL   AV          P G  F T +  D + + W  P        + Y
Sbjct: 18175 FAENRYGKSAPLDSKAVIVQYPFKEPGPPGTPFVTSISKDQMLVQWHEPVNDGGTKIIGY 18234

Query: 1667  SSPEDGIHELF-------PAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQS 1719
                +   + +        P  D +  T    GL  G EY   V A +     +P   ++ 
Sbjct: 18235 HLEQKEKNSILWVKLNKTPIQDTKFKTT---GLDEGLEYEFKVSAENIVGIGKPSKVSEC 18291

Query: 1720  TAIPAPTDL----KFTQVTPTSLSAQWTPP----NVQLTGYRVRVTPKEKTGPMKEINLA 1771
                  P D     +   +T  +++ +W  P      ++TGY V          MK     
Sbjct: 18292 FVARDPCDPPGRPEAIVITRNNVTLKWKKPAYDGGSKITGYIVEKKDLPDGRWMKASFTN 18351

Query: 1772  PDSSSVVVSGLMVATKYEVSVYALKDTLT-SRPAQ--GVVTTLENVSPPRRAR------- 1821
                +   VSGL+   +YE  V A       S P+   G +T  + +  P  +        
Sbjct: 18352 VLETEFTVSGLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARDEIDAPNASLDPKYKDV 18411

Query: 1822  -VTDATET-TITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQP-GTD 1878
              V  A ET  +    R K      +  D      +T  +  IK  ++  T+       TD
Sbjct: 18412 IVVHAGETFVLEADIRGKPIPDVVWSKDGKELE-ETAARMEIKSTIQKTTLVVKDCIRTD 18470

Query: 1879  YKIYLYTLND--NARSSPVVIDASTAIDAPSN-LRFLATTPNSLLVSWQPPR----ARIT 1931
                Y+  L++    +S P+ +        P   L+    T     ++W PP     A I+
Sbjct: 18471 GGQYILKLSNVGGTKSIPITVKVLDRPGPPEGPLKVTGVTAEKCYLAWNPPLQDGGANIS 18530

Query: 1932  GYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPL 1985
              YII+  +        V      +    +T L PG EY   V+A+      EPL
Sbjct: 18531 HYIIEKRETSRLSWTQVSTEVQALNYK-VTKLLPGNEYIFRVMAVNKYGIGEPL 18583



 Score = 78.6 bits (192), Expect = 7e-14
 Identities = 169/767 (22%), Positives = 275/767 (35%), Gaps = 120/767 (15%)

Query: 601   PLQTYPSSSGPVEVFITETPSQPN-------SHPIQWNAPQ---PSHISKYILRWRPKNS 650
             P +T P       VF+   PS+P        +  I W  P     + I+ Y + ++  + 
Sbjct: 19763 PSETSPLIRAEDPVFLPSPPSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEYKKSDD 19822

Query: 651   VGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNT 710
                WK +        YTI GL  G  Y  ++ S+ + G  +        + +S P  +  
Sbjct: 19823 TD-WKTSIQSLRGTEYTISGLTTGAEYVFRVKSVNKVGASD-------PSDSSDPQIAKE 19874

Query: 711   VTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVS--GFRVEYELSEEGDEP----Q 764
                E     PL       +E+  +  V +  S + TV   G  V   L  + D       
Sbjct: 19875 REEE-----PLFDID---SEMRKTLIVKAGASFTMTVPFRGRPVPNVLWSKPDTDLRTRA 19926

Query: 765   YLDLPSTATSVNIPDLL--PGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQV 822
             Y+D   + TS+ I +       KY + +  +      +L++    T  P  P + TV  V
Sbjct: 19927 YVDTTDSRTSLTIENANRNDSGKYTLTIQNVLSAASLTLVVKVLDTPGP--PTNITVQDV 19984

Query: 823   DDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNI 878
                S V+ W  P+    AP+  Y I    + + +   +       S  +++LQ G  Y  
Sbjct: 19985 TKESAVLSWDVPENDGGAPVKNYHIEKREASKKAWVSVTNNCNRLSYKVTNLQEGAIYYF 20044

Query: 879   TIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAV 934
              +    E     P   ++   G   ++    P  L    ++   V++ W  PE    S +
Sbjct: 20045 RVSGENEFGVGIPAETKE---GVKITEKPSPPEKLGVTSISKDSVSLTWLKPEHDGGSRI 20101

Query: 935   TGYRVDVIPVNLPGEHGQR----LPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKP-- 988
               Y V+ +      E GQ+      ++++T   V+GL     Y+F+VFA +    S P  
Sbjct: 20102 VHYVVEAL------EKGQKNWVKCAVAKSTHHVVSGLRENSEYFFRVFAENQAGLSDPRE 20155

Query: 989   -LTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPS 1047
              L      +   P  +   N    TV VR         G  L V +   G+P    V  S
Sbjct: 20156 LLLPVLIKEQLEPPEIDMKNFPSHTVYVR--------AGSNLKVDIPISGKPLP-KVTLS 20206

Query: 1048  VSKYPLR-NLQPASEYTV---------SLVAIKGNQESPKATGVFTTL---------QPG 1088
                 PL+  ++  +E T          S+ A  G  E   A    TT          +PG
Sbjct: 20207 RDGVPLKATMRFNTEITAENLTINLKESVTADAGRYEITAANSSGTTKAFINIVVLDRPG 20266

Query: 1089  SSI-PPYNTEVTETTIVITWTPAPRIG-------FKLGVRPSQGGEAPREVTSDSGSIVV 1140
                 P   +++TE ++ + W P    G         L    S         T     + V
Sbjct: 20267 PPTGPVVISDITEESVTLKWEPPKYDGGSQVTNYILLKRETSTAVWTEVSATVARTMMKV 20326

Query: 1141  SGLTPGVEYVYTIQV-----LRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSW 1195
               LT G EY + I+      + D  +     V    T   PP+   +  N     +TV W
Sbjct: 20327 MKLTTGEEYQFRIKAENRFGISDHIDSACVTVKLPYTTPGPPSTPWV-TNVTRESITVGW 20385

Query: 1196  ERSTT---PDITGYRITTTPTNG---QQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYT 1249
                 +     + GY +     N    Q+ N L  V+       T   +S GL Y   VY 
Sbjct: 20386 HEPVSNGGSAVVGYHLEMKDRNSILWQKANKL--VIRTTHFKVT--TISAGLIYEFRVYA 20441

Query: 1250  V------KDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPP 1290
                    K    S P+    I A  PP ++R T+I  +++ ++W  P
Sbjct: 20442 ENAAGVGKPSHPSEPV--LAIDACEPPRNVRITDISKNSVSLSWQQP 20486



 Score = 77.8 bits (190), Expect = 1e-13
 Identities = 327/1588 (20%), Positives = 561/1588 (35%), Gaps = 285/1588 (17%)

Query: 737   VVSWVSASDT----VSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQ 792
             +++W    D     ++GF +E + ++     Q ++  +  +  +I  LL G++Y   V  
Sbjct: 8909  LLNWSDPEDDGGSEITGFIIERKDAKMHTWRQPIE--TERSKCDITGLLEGQEYKFRVIA 8966

Query: 793   ISEDG-----EQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQA----PITGYRI 843
              ++ G     E   IL+      P +P   T  +   ++I + W  P++    PI GY I
Sbjct: 8967  KNKFGCGPPVEIGPILAVDPLGPPTSPERLTYTERTKSTITLDWKEPRSNGGSPIQGYII 9026

Query: 844   VY----SPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTP-----VVI 894
                    P  E  +  L  P T  S  + +L     Y   + AV E  ES P     VVI
Sbjct: 9027  EKRRHDKPDFERVNKRL-CPTT--SFLVENLDEHQMYEFRVKAVNEIGESEPSLPLNVVI 9083

Query: 895   QQETTG-------TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLP 947
             Q +          + R DT+     ++  E   +   +   P           VI     
Sbjct: 9084  QDDEVPPTIKLRLSVRGDTIK----VKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTD 9139

Query: 948   GEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSH----GRESKPLTAQQTTKLDAPTNL 1003
                  +  +SR+       +   V      + V+     G   + +  +   +   P NL
Sbjct: 9140  ALQITKEEVSRSEAKTELSIPKAVREDKGTYTVTASNRLGSVFRNVHVEVYDRPSPPRNL 9199

Query: 1004  QFVNETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSV--SKYPLRNLQ 1057
                +    +  + W  P     ++IT Y +      R +     V  +    +Y +  L 
Sbjct: 9200  AVTDIKAESCYLTWDAPLDNGGSEITHYVIDKRDASRKKAEWEEVTNTAVEKRYGIWKLI 9259

Query: 1058  PASEYTVSLVAIKGNQESPKATGVFTTLQ-----PGSSIPPYNTEVTETTIVITWTP--- 1109
             P  +Y   + A+     S +       +Q     PG    P     T+ +++++WTP   
Sbjct: 9260  PNGQYEFRVRAVNKYGISDECKSDKVVIQDPYRLPGPPGKPKVLARTKGSMLVSWTPPLD 9319

Query: 1110  ---APRIGFKLGVRP------SQGGEAPREVTSDSG-SIVVSGLTPGVEYVYTIQVLR-- 1157
                +P  G+ L  R       S+   AP       G    V  L  GV+Y +    +   
Sbjct: 9320  NGGSPITGYWLEKREEGSPYWSRVSRAPITKVGLKGVEFNVPRLLEGVKYQFRAMAINAA 9379

Query: 1158  ----DGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWE---RSTTPDITGYRITT 1210
                   +  D  +    + P  PP+   ++    + + ++ W+   +     I GY +  
Sbjct: 9380  GIGPPSEPSDPEVAGDPIFPPGPPSCPEVKDKTKSSI-SLGWKPPAKDGGSPIKGYIVEM 9438

Query: 1211  TP---TNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAV 1267
                  T+ ++ N  ++++   +  C   NL    +Y   V  V +  ES P SDT     
Sbjct: 9439  QEEGTTDWKRVNEPDKLITTCE--CVVPNLKELRKYRFRVKAVNEAGESEP-SDTT--GE 9493

Query: 1268  PPPTDLR-----FTNIGPDTMRVTWA-------------PPPS----IDLTNFLVRYSPV 1305
              P TD++     F +IG     V  A             P P      D          V
Sbjct: 9494  IPATDIQEEPEVFIDIGAQDCLVCKAGSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGV 9553

Query: 1306  KNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTP-LRGRQKTGLDSPTGI 1364
              +  + A+L  + + + +++           S+++  +  + T   R +       P  +
Sbjct: 9554  HDIPEDAQLETAENSSVIIIPECKRSHTGKYSITAKNKAGQKTANCRVKVMDVPGPPKDL 9613

Query: 1365  DFSDITANSFTVHWIAPRAT----ITGYRIRHHPEHFSGRPREDRVPH-SRNSITLTNLT 1419
               SDIT  S  + W  P       I GY I        G+      P     +  + +L 
Sbjct: 9614  KVSDITRGSCRLSWKMPDDDGGDRIKGYVIEKRT--IDGKAWTKVNPDCGSTTFVVPDLL 9671

Query: 1420  PGTEYVVSIVALNGREESPLLIGQQSTVS-------DVPRDLEVVAATPTSLLISWDAPA 1472
                +Y   + A N     P +   Q T +       D P  L++   T  ++ +SW  P 
Sbjct: 9672  SEQQYFFRVRAENRFGIGPPVETIQRTTARDPIYPPDPPIKLKIGLITKNTVHLSWKPP- 9730

Query: 1473  VTVRYYRITYGETGGNSPVQEFTVP-------GSKSTA--------------TISGLKPG 1511
                        +  G SPV  + V        G+K  A              T+  L  G
Sbjct: 9731  -----------KNDGGSPVTHYIVECLAWDPTGTKKEAWRQCNKRDVEELQFTVEDLVEG 9779

Query: 1512  VDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTG 1571
              +Y   V AV   G S  S+             P   Q  D+   SI +K        T 
Sbjct: 9780  GEYEFRVKAVNAAGVSKPSATV----------GPCDCQRPDMPP-SIDLKEFMEVEEGTN 9828

Query: 1572  YRVTTTPKNGPGPT----KTKTAGPDQTEMTIEGLQPTVEYV----VSVYAQNPSGESQP 1623
               +    K  P PT    K     PD  E  +         V      V  Q+   ++  
Sbjct: 9829  VNIVAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDTGL 9888

Query: 1624  LVQTAVTNIDR---------------PKG-LAFTDVDVDSIKIAWESPQ----GQVSRYR 1663
                TAV N+                 P G + F  V  D + ++W  P+     +++ Y 
Sbjct: 9889  YTITAVNNLGTASKEMRLNVLGRPGPPVGPIKFESVSADQMTLSWFPPKDDGGSKITNYV 9948

Query: 1664  VTY--SSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVA-----LHDDMESQPLIG 1716
             +    ++ +  +H    + + +E T  +  L  G EY   ++A     + + ++S+P   
Sbjct: 9949  IEKREANRKTWVHV---SSEPKECTYTIPKLLEGHEYVFRIMAQNKYGIGEPLDSEPETA 10005

Query: 1717  TQSTAIP-APTDLKFTQVTPTSLSAQWTPPNVQ----LTGYRVRVTPKEKTGPM-KEINL 1770
                 ++P AP     + VT  S++  W  P       +TGY + +  K+ T    K +N 
Sbjct: 10006 RNLFSVPGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPVTGYWLEM--KDTTSKRWKRVNR 10063

Query: 1771  APDSS-----SVVVSGLMVATKYEVSVYALKD------TLTSRPAQGVVTTLENVSPPRR 1819
              P  +     S  V+GL+  + Y+  VYA+        +L S PA    T  + ++PP  
Sbjct: 10064 DPIKAMTLGVSYKVTGLIEGSDYQFRVYAINAAGVGPASLPSDPA----TARDPIAPPGP 10119

Query: 1820  A--RVTDATETTITISWRTKTET----ITGFQVDAVPANGQTPIQRTIKPDVRS--YTIT 1871
                +VTD T+++  + W    +     +TG+ V+     G+   ++    +VR     +T
Sbjct: 10120 PFPKVTDWTKSSADLEWSPPLKDGGSKVTGYIVE-YKEEGKEEWEKGKDKEVRGTKLVVT 10178

Query: 1872  GLQPGTDYKIYLYTLNDNARSSPV----VIDASTAIDAPSNLRFLATTPNSLLVSWQPPR 1927
             GL+ G  YK  +  +N      P     VI+    + +P +L+  A+  + ++V      
Sbjct: 10179 GLKEGAFYKFRVRAVNIAGIGEPGEVTDVIEMKDRLVSP-DLQLDASVRDRIVVH-AGGV 10236

Query: 1928  ARITGYIIKYEKPGSPPREVV--PRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPL 1985
              RI  Y+      G PP  V      R    EATI      T      + +KN Q+S   
Sbjct: 10237 IRIIAYV-----SGKPPPTVTWNMNERTLPQEATIE-----TTAISSSMVIKNCQRSHQG 10286

Query: 1986  I----------GRKKTV----------QKTPFVTHPGYDTGNGIQL----PGTSGQQPSV 2021
             +           RKKT+            TPF+ H    T    +L    P   G  P +
Sbjct: 10287 VYSLLAKNEAGERKKTIIVDVLDVPGPVGTPFLAHNL--TNESCKLTWFSPEDDGGSP-I 10343

Query: 2022  GQQMIFEEHGFRRTTPPTTATPIRHRPRPYPPNVGQ----EALSQTTISWAPFQDTSEYI 2077
                +I +    RR   P T T  R          G+       ++ +I   PF +TSE +
Sbjct: 10344 TNYVIEKRESDRRAWTPVTYTVTRQNATVQGLIQGKAYFFRIAAENSIGMGPFVETSEAL 10403

Query: 2078  ISCHPVGTDEEPLQFRVPG-TSTSATLT 2104
             +   P+   E P    V   T  + TLT
Sbjct: 10404 VIREPITVPERPEDLEVKEVTKNTVTLT 10431



 Score = 77.0 bits (188), Expect = 2e-13
 Identities = 270/1352 (19%), Positives = 474/1352 (35%), Gaps = 184/1352 (13%)

Query: 679   GQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFS-PLVATSESVTEITASSFV 737
             G  + I+   H++   +  T  +   P  S TV+ +      P       V+EI   S  
Sbjct: 10966 GSKLEIRNAAHEDGGIYSLTVEN---PAGSKTVSVKVLVLDKPGPPRDLEVSEIRKDSCY 11022

Query: 738   VSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVN----IPDLLPGRKYIVNVYQI 793
             ++W    D        Y + E  D       P +ATS         L  G +Y+  V   
Sbjct: 11023 LTWKEPLDDGGSVITNYVV-ERRDVASAQWSPLSATSKKKSHFAKHLNEGNQYLFRVAAE 11081

Query: 794   SEDGEQSLILSTSQTTAPDA--PPDPTVD----QVDDTSIVVRWSRPQ----APITGYRI 843
             ++ G    + +     A D   PP P  D     VD T + + W++P     +PITGY +
Sbjct: 11082 NQYGRGPFVETPKPIKALDPLHPPGPPKDLHHVDVDKTEVSLVWNKPDRDGGSPITGYLV 11141

Query: 844   VYSPSVEGSSTELNLPETAN-SVTLSDLQPGVQYNITIYA---VEENQESTPVVIQQETT 899
              Y    EG+   +      N    ++ LQ G  Y   + A   V      T + I+ +  
Sbjct: 11142 EYQE--EGTQDWIKFKTVTNLECVVTGLQQGKTYRFRVKAENIVGLGLPDTTIPIECQEK 11199

Query: 900   GTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEH---GQRLPI 956
               P S  +    D++ +E   VK       P + + G  V        G      +   +
Sbjct: 11200 LVPPSVEL----DVKLIEGLVVKAGTTVRFP-AIIRGVPVPTAKWTTDGSEIKTDEHYTV 11254

Query: 957   SRNTFAEVTGLSPGV---TYYFKVFAVSHGRESKPLTAQQTTKLDAPTN----LQFVNET 1009
               + F+ V  +   +   T  +++  VS+   SK + A   T LD P      +  ++ T
Sbjct: 11255 ETDNFSSVLTIKNCLRRDTGEYQI-TVSNAAGSKTV-AVHLTVLDVPGPPTGPINILDVT 11312

Query: 1010  DSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVS 1065
                + + W PP+    + +  Y +    TR+      + G S +K  + +LQ   EY   
Sbjct: 11313 PEHMTISWQPPKDDGGSPVINYIVEKQDTRKDTWGVVSSGSSKTKLKIPHLQKGCEYVFR 11372

Query: 1066  LVAIKGNQESPKATGVFTTLQPGSSIP-----PYNTEVTETTIVITWT------PAPRIG 1114
             + A       P      T  +   S P     P  T++TE    ++WT       +P  G
Sbjct: 11373 VRAENKIGVGPPLDSTPTVAKHKFSPPSPPGKPVVTDITENAATVSWTLPKSDGGSPITG 11432

Query: 1115  FKLGVRPSQGGEAPREVTSDSG-SIVVSGLTPGVEYVYTIQVLR-DGQERDAPIVNKV-- 1170
             + +  R   G       T  +     V+GL  G  Y + +      G  + +P  + +  
Sbjct: 11433 YYMERREVTGKWVRVNKTPIADLKFRVTGLYEGNTYEFRVFAENLAGLSKPSPSSDPIKA 11492

Query: 1171  ---VTPLSPPTNLHLEANPDTGVLTVSWERSTTPD---ITGYRITTTPTNGQQGNSLEEV 1224
                + P  PP N  L+ +       + W +  +     I GY +        Q N + + 
Sbjct: 11493 CRPIKPPGPPINPKLK-DKSRETADLVWTKPLSDGGSPILGYVVECQKPGTAQWNRINKD 11551

Query: 1225  VHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVP--ISDTIIPAV---PPPTDLRFTNIG 1279
                 Q +     L  G EY   +       E  P  +++++I      PP  +L  T   
Sbjct: 11552 ELIRQCAFRVPGLIEGNEYRFRIKAANIVGEGEPRELAESVIAKDILHPPEVELDVTCRD 11611

Query: 1280  PDTMRVTWA----------PPPSIDLTN---FLVRYSPVKNEEDV--AELSISPSDNAVV 1324
               T+RV             P P I  T     LVR   V   +D+   EL I  +  A  
Sbjct: 11612 VITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRA-- 11669

Query: 1325  LTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSP---TGIDFSDITANSFTVHWIAP 1381
                     +Y++S  +     + + +       LD P     +  +++T  + T+ W  P
Sbjct: 11670 -----DHGKYIISAKNSSGHAQGSAI----VNVLDRPGPCQNLKVTNVTKENCTISWENP 11720

Query: 1382  R----ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNG---- 1433
                  + IT + + +   +  G          R  +   NL    EY   + A N     
Sbjct: 11721 LDNGGSEITNFIVEYRKPNQKGWSIVASDVTKR--LIKANLLANNEYYFRVCAENKVGVG 11778

Query: 1434  ---REESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYG---ETGG 1487
                  ++P+L          P +L +     T + + W  P        ++Y       G
Sbjct: 11779 PTIETKTPILAINPIDRPGEPENLHIADKGKTFVYLKWRRPDYDGGSPNLSYHVERRLKG 11838

Query: 1488  NSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASS--KPISINYRTEIDKP 1545
             +   +       K T  +  +   V+  I  + V  + +   S   K   +  + ++ KP
Sbjct: 11839 SDDWERVHKGSIKETHYM--VDRCVENQIYEFRVQTKNEGGESDWVKTEEVVVKEDLQKP 11896

Query: 1546  SQMQVTDVQDNSIS-VKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMT------ 1598
                    V D  +S V  + +   +   R+    +  P P    T   D T++T      
Sbjct: 11897 -------VLDLKLSGVLTVKAGDTI---RLEAGVRGKPFPEVAWTKDKDATDLTRSPRVK 11946

Query: 1599  IEGLQPTVEYVVSVYAQNPSGE--------SQPLVQTAVTNI-DRP---KGLAFTDVDVD 1646
             I+    + ++ ++   ++  G+        +   V  A  N+ D+P   + L   DV  D
Sbjct: 11947 IDTRADSSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATVNVLDKPGPVRNLKIVDVSSD 12006

Query: 1647  SIKIAWESPQG----QVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSV 1702
                + W+ P+     ++  Y +     +  +   + A      T   + L  G+EY   V
Sbjct: 12007 RCTVCWDPPEDDGGCEIQNYILEKCETKRMVWSTYSATVLTPGTTVTR-LIEGNEYIFRV 12065

Query: 1703  -----VALHDDMESQPLIGTQSTAIPA-PTDLKFTQVTPTSLSAQWTPPNVQ----LTGY 1752
                  +      ES+P+I       P  P   + T+V+   ++  W PP       +TGY
Sbjct: 12066 RAENKIGTGPPTESKPVIAKTKYDKPGRPDPPEVTKVSKEEMTVVWNPPEYDGGKSITGY 12125

Query: 1753  RVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKD------TLTSRPAQG 1806
              +    K  T  +     A     + V  L+   +Y+  V A  +      +L SRP   
Sbjct: 12126 FLEKKEKHSTRWVPVNKSAIPERRMKVQNLLPDHEYQFRVKAENEIGIGEPSLPSRPVVA 12185

Query: 1807  VVTTLENVSPPRRARVTDATETTITISWRTKT----ETITGFQV-------DAVPANGQT 1855
                 +E   PP   RV D T+ +IT+ W          I G+ V       DA P  G  
Sbjct: 12186 K-DPIEPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAPIIGYVVEMRPKIADASPDEGWK 12244

Query: 1856  PIQRTIKPDVRSYTITGLQPGTDYKIYLYTLN 1887
                   +   + +T+T L    +Y+  +   N
Sbjct: 12245 RCNAAAQLVRKEFTVTSLDENQEYEFRVCAQN 12276



 Score = 75.9 bits (185), Expect = 4e-13
 Identities = 162/749 (21%), Positives = 272/749 (36%), Gaps = 110/749 (14%)

Query: 1233  TFDNLSPGLEYNVSVYTVKDDKESVPIS-----DTIIPAVPPPTDLRF-------TNI-- 1278
             T ++L  G EY   V  V     S P +     D   P +PP  DL+        TN+  
Sbjct: 9772  TVEDLVEGGEYEFRVKAVNAAGVSKPSATVGPCDCQRPDMPPSIDLKEFMEVEEGTNVNI 9831

Query: 1279  -----GPDTMRVTW--APPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPG 1331
                  G     +TW  APP   D         PV  +  V +L +  +   V+  +    
Sbjct: 9832  VAKIKGVPFPTLTWFKAPPKKPD------NKEPVLYDTHVNKLVVDDTCTLVIPQSRRSD 9885

Query: 1332  TEY--VVSVSSVYEQHESTPLRGRQKTGLDSPTG-IDFSDITANSFTVHWIAPR----AT 1384
             T    + +V+++    +   L    + G   P G I F  ++A+  T+ W  P+    + 
Sbjct: 9886  TGLYTITAVNNLGTASKEMRLNVLGRPG--PPVGPIKFESVSADQMTLSWFPPKDDGGSK 9943

Query: 1385  ITGYRIRHHPE------HFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGR---- 1434
             IT Y I           H S  P+E        + T+  L  G EYV  I+A N      
Sbjct: 9944  ITNYVIEKREANRKTWVHVSSEPKEC-------TYTIPKLLEGHEYVFRIMAQNKYGIGE 9996

Query: 1435  --EESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVT----VRYYRITYGETGGN 1488
               +  P       +V   P    V + T  S+ ++W+ P       V  Y +   +T   
Sbjct: 9997  PLDSEPETARNLFSVPGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPVTGYWLEMKDTTSK 10056

Query: 1489  -------SPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPAS--SKPISINYR 1539
                     P++  T+  S     ++GL  G DY   VYA+   G  PAS  S P +    
Sbjct: 10057 RWKRVNRDPIKAMTLGVSYK---VTGLIEGSDYQFRVYAINAAGVGPASLPSDPATARDP 10113

Query: 1540  TEIDKPSQMQVTDVQDNSISVKWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQT 1595
                  P   +VTD   +S  ++W P      S VTGY V    +      K K      T
Sbjct: 10114 IAPPGPPFPKVTDWTKSSADLEWSPPLKDGGSKVTGYIVEYKEEGKEEWEKGKDKEVRGT 10173

Query: 1596  EMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVD-SIKIAWES 1654
             ++ + GL+    Y   V A N +G  +P   T V  I+    L   D+ +D S++     
Sbjct: 10174 KLVVTGLKEGAFYKFRVRAVNIAGIGEPGEVTDV--IEMKDRLVSPDLQLDASVRDRIVV 10231

Query: 1655  PQGQVSRY----------RVTYSSPEDGI-HELFPAPDGEEDTAELQGLRPGSEYTVSVV 1703
               G V R            VT++  E  +  E          +  ++  +   +   S++
Sbjct: 10232 HAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEATIETTAISSSMVIKNCQRSHQGVYSLL 10291

Query: 1704  ALHDDMESQPLIGTQSTAIPAPTDLKFT--QVTPTSLSAQWTPP----NVQLTGYRVRVT 1757
             A ++  E +  I      +P P    F    +T  S    W  P       +T Y +   
Sbjct: 10292 AKNEAGERKKTIIVDVLDVPGPVGTPFLAHNLTNESCKLTWFSPEDDGGSPITNYVIEKR 10351

Query: 1758  PKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRP---AQGVVTTLENV 1814
               ++      +       +  V GL+    Y   + A ++++   P       +   E +
Sbjct: 10352 ESDRRA-WTPVTYTVTRQNATVQGLIQGKAYFFRI-AAENSIGMGPFVETSEALVIREPI 10409

Query: 1815  SPPRR---ARVTDATETTITISWRTKT----ETITGFQVDAVPANGQTPIQRTIKPDV-- 1865
             + P R     V + T+ T+T++W          I  + +++    G     +    ++  
Sbjct: 10410 TVPERPEDLEVKEVTKNTVTLTWNPPKYDGGSEIINYVLES-RLIGTEKFHKVTNDNLLS 10468

Query: 1866  RSYTITGLQPGTDYKIYLYTLNDNARSSP 1894
             R YT+ GL+ G  Y+  +  +N   +  P
Sbjct: 10469 RKYTVKGLKEGDTYEYRVSAVNIVGQGKP 10497



 Score = 74.3 bits (181), Expect = 1e-12
 Identities = 171/843 (20%), Positives = 321/843 (38%), Gaps = 99/843 (11%)

Query: 1141  SGLTPGVEYVYTIQVLRDG----QERDAPIV---NKVVTPLSPPTNLHLEANPDTGVLTV 1193
             +GL  G EY Y +              +P++   + V  P SPP+   +  +  T  +T+
Sbjct: 19740 TGLREGCEYEYRVYAENAAGLSLPSETSPLIRAEDPVFLP-SPPSKPKIVDSGKT-TITI 19797

Query: 1194  SWERSTTPD---ITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTV 1250
             +W +        ITGY +    ++     +  + +   +   T   L+ G EY   V +V
Sbjct: 19798 AWVKPLFDGGAPITGYTVEYKKSDDTDWKTSIQSLRGTEY--TISGLTTGAEYVFRVKSV 19855

Query: 1251  KDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFL-VRYSPVKN-- 1307
                  S P SD+  P +    +          MR T         T  +  R  PV N  
Sbjct: 19856 NKVGASDP-SDSSDPQIAKEREEEPLFDIDSEMRKTLIVKAGASFTMTVPFRGRPVPNVL 19914

Query: 1308  ----EEDVAELS-ISPSDNAVVLT----NLLPGTEYVVSVSSVYEQHESTPLRGRQKTGL 1358
                 + D+   + +  +D+   LT    N     +Y +++ +V      T +     T  
Sbjct: 19915 WSKPDTDLRTRAYVDTTDSRTSLTIENANRNDSGKYTLTIQNVLSAASLTLVVKVLDTP- 19973

Query: 1359  DSPTGIDFSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRNSIT 1414
               PT I   D+T  S  + W  P     A +  Y I       + +     V ++ N ++
Sbjct: 19974 GPPTNITVQDVTKESAVLSWDVPENDGGAPVKNYHIEKRE---ASKKAWVSVTNNCNRLS 20030

Query: 1415  --LTNLTPGTEYVVSIVALNGREESPLLIGQQSTVS-------DVPRDLEVVAATPTSLL 1465
               +TNL  G  Y   +   +G  E  + I  ++            P  L V + +  S+ 
Sbjct: 20031 YKVTNLQEGAIYYFRV---SGENEFGVGIPAETKEGVKITEKPSPPEKLGVTSISKDSVS 20087

Query: 1466  ISWDAP----AVTVRYYRITYGETGGNSPVQEFTVPGSKSTA-TISGLKPGVDYTITVYA 1520
             ++W  P       + +Y +   E G  + V+      +KST   +SGL+   +Y   V+A
Sbjct: 20088 LTWLKPEHDGGSRIVHYVVEALEKGQKNWVK---CAVAKSTHHVVSGLRENSEYFFRVFA 20144

Query: 1521  VTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKW---LPSSSPVTGYRVTTT 1577
                 G S      + +  + +++ P ++ + +   +++ V+    L    P++G  +   
Sbjct: 20145 ENQAGLSDPRELLLPVLIKEQLEPP-EIDMKNFPSHTVYVRAGSNLKVDIPISGKPLPKV 20203

Query: 1578  PKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVS-------VYAQNPSGESQPLVQTAVT 1630
               +  G    K      TE+T E L   ++  V+       + A N SG ++  +   V 
Sbjct: 20204 TLSRDG-VPLKATMRFNTEITAENLTINLKESVTADAGRYEITAANSSGTTKAFINIVV- 20261

Query: 1631  NIDRPKG----LAFTDVDVDSIKIAWESPQ----GQVSRYRVTYSSPEDGIHELFPAPDG 1682
              +DRP      +  +D+  +S+ + WE P+     QV+ Y +        +     A   
Sbjct: 20262 -LDRPGPPTGPVVISDITEESVTLKWEPPKYDGGSQVTNYILLKRETSTAVWTEVSATVA 20320

Query: 1683  EEDTAELQGLRPGSEYTVSVVA-----LHDDMESQPLIGTQSTAIPAPTDLKF-TQVTPT 1736
                  ++  L  G EY   + A     + D ++S  +        P P    + T VT  
Sbjct: 20321 RT-MMKVMKLTTGEEYQFRIKAENRFGISDHIDSACVTVKLPYTTPGPPSTPWVTNVTRE 20379

Query: 1737  SLSAQWTPP----NVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSV 1792
             S++  W  P       + GY + +  +      K   L   ++   V+ +     YE  V
Sbjct: 20380 SITVGWHEPVSNGGSAVVGYHLEMKDRNSILWQKANKLVIRTTHFKVTTISAGLIYEFRV 20439

Query: 1793  YALKDTLTSRPAQGV--VTTLENVSPPRRARVTDATETTITISWRTKT----ETITGFQV 1846
             YA       +P+     V  ++   PPR  R+TD ++ ++++SW+         ITG+ V
Sbjct: 20440 YAENAAGVGKPSHPSEPVLAIDACEPPRNVRITDISKNSVSLSWQQPAFDGGSKITGYIV 20499

Query: 1847  DA--VPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLN--DNARSSPVVIDASTA 1902
             +   +P    T    T   + + + I+GL   + Y+  ++  N   +  +   V+   T 
Sbjct: 20500 ERRDLPDGRWTKASFTNVTETQ-FIISGLTQNSQYEFRVFARNAVGSISNPSEVVGPITC 20558

Query: 1903  IDA 1905
             ID+
Sbjct: 20559 IDS 20561



 Score = 65.5 bits (158), Expect = 6e-10
 Identities = 290/1521 (19%), Positives = 542/1521 (35%), Gaps = 205/1521 (13%)

Query: 628   IQWNAPQ---PSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISI 684
             + W+AP     S ++ + +  + +NS+   K  T P     Y   GL  G+ Y+ ++ + 
Sbjct: 21470 LTWDAPVYDGGSEVTGFHVEKKERNSILWQKVNTSPISGREYRATGLVEGLDYQFRVYAE 21529

Query: 685   QQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSAS 744
                G              S+P   +  T   +P  P    +    ++T  +  + W    
Sbjct: 21530 NSAG-------------LSSPSDPSKFTLAVSPVDP--PGTPDYIDVTRETITLKWNPPL 21574

Query: 745   DTVSGFRVEYELSEEGDEPQYLDLPSTATS---VNIPDLLPGRKYIVNVYQ------ISE 795
                    V Y + +     +++    T  S     +  L PG +Y   +        IS 
Sbjct: 21575 RDGGSKIVGYSIEKRQGNERWVRCNFTDVSECQYTVTGLSPGDRYEFRIIARNAVGTISP 21634

Query: 796   DGEQSLILSTSQTTAPDAPPDPTVD---QVDDTSIVVRWS--RPQAPITGYRIV----YS 846
               + S I+ T     P     P V+   +  D  I+      R +A + G  +     + 
Sbjct: 21635 PSQSSGIIMTRDENVP-----PIVEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVTWFK 21689

Query: 847   PSVE-GSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQES--TPVVIQQETTGTPR 903
               VE      + + +   S +L  ++   + +  +Y VE    S      I+ +   TP 
Sbjct: 21690 DGVEIEKRMNMEITDVLGSTSLF-VRDATRDHRGVYTVEAKNASGSAKAEIKVKVQDTPG 21748

Query: 904   SDTVPSPRDLQFVEVTDVKVTIMWTPPES----AVTGYRVDVIPVNLPGEHGQRLPISRN 959
                 P    ++F  +T  K+T+ W  P +     +T Y ++    +              
Sbjct: 21749 KVVGP----IRFTNITGEKMTLWWDAPLNDGCAPITHYIIEKRETSRLAWALIEDKCEAQ 21804

Query: 960   TFAEVTGLSPGVTYYFKVFAVSH---GR--ESKPLTAQ-QTTKLDAPTNLQFVNETDSTV 1013
             ++  +  L  G  Y F+V AV+    GR  +S P+ AQ Q T  DAP   +  N T +++
Sbjct: 21805 SYTAIK-LINGNEYQFRVSAVNKFGVGRPLDSDPVVAQIQYTVPDAPGIPEPSNITGNSI 21863

Query: 1014  LVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRN-------LQPASEYTVSL 1066
              + W  P +   G  +   +  R + +       +SK P+         L   +EY   +
Sbjct: 21864 TLTWARPESD-GGSEIQQYILERREKKSTRWVKVISKRPISETRFKVTGLTEGNEYEFHV 21922

Query: 1067  VAIKGNQESPKATGVFTTLQ-------PGSSIPPYNTEVTETTIVITWTPA------PRI 1113
             +A       P A+G+   ++       PG       T+ ++TT+ + W+          I
Sbjct: 21923 MAENAAGVGP-ASGISRLIKCREPVNPPGPPTVVKVTDTSKTTVSLEWSKPVFDGGMEII 21981

Query: 1114  GFKLGVRPSQGGEAPREVTSDS---GSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKV 1170
             G+ + +  +  G+   +V +++       V+ L  G EY + +  +    + D+  V   
Sbjct: 21982 GYIIEMCKADLGDW-HKVNAEACVKTRYTVTDLQAGEEYKFRVSAINGAGKGDSCEVTGT 22040

Query: 1171  VTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPT----NGQQGNSLEEVVH 1226
             +  +   T   L+ + +     V    ++      Y+   TPT          SL   +H
Sbjct: 22041 IKAVDRLTAPELDIDANFKQTHVVRAGASIRLFIAYQGRPTPTAVWSKPDSNLSLRADIH 22100

Query: 1227  ADQSSCTFD----NLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRFTNIGPDT 1282
                S  T      N +   +Y ++V      K S+  +  ++    PP  + F ++   +
Sbjct: 22101 TTDSFSTLTVENCNRNDAGKYTLTVENNSGSK-SITFTVKVLDTPGPPGPITFKDVTRGS 22159

Query: 1283  MRVTWAPPPSIDLTNFLVRYSPVKNEEDVAE---LSISPSDNAVVLTNLLPGTEYVVSVS 1339
               + W   P +D    +  Y   K E        +S   +     + +L  G  Y   VS
Sbjct: 22160 ATLMW-DAPLLDGGARIHHYVVEKREASRRSWQVISEKCTRQIFKVNDLAEGVPYYFRVS 22218

Query: 1340  SVYEQHESTPLRGRQKTGLDS----PTGIDFSDITANSFTVHWIAPR----ATITGYRIR 1391
             +V E     P    +          P  +D  D + +S  + W+ P     + ITGY + 
Sbjct: 22219 AVNEYGVGEPYEMPEPIVATEQPAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRITGYLLE 22278

Query: 1392  HHPEHFSGRPREDRVPHSRN-SITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDV 1450
                +   G        H++  + T+  L   TEY   + A N    S       S +   
Sbjct: 22279 MRQK---GSDFWVEAGHTKQLTFTVERLVEKTEYEFRVKAKNDAGYSEPREAFSSVIIKE 22335

Query: 1451  PR-----DLEVV--------AATPTSL---LISWDAPAVTVRYYRITYGETGGNSPVQEF 1494
             P+     DL  +        A +P ++   +    AP VT +   +   ET   S     
Sbjct: 22336 PQIEPTADLTGITNQLITCKAGSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVS----I 22391

Query: 1495  TVPGSKSTATISGLKPGVD--YTITVYAVTGRGDSPASSKPISINYRTEIDKPSQM---- 1548
             T    ++T T+     G    Y +T+       ++ A  K  S+     I +P  +    
Sbjct: 22392 TTTKDRTTLTVKDSMRGDSGRYFLTL-------ENTAGVKTFSVTV-VVIGRPGPVTGPI 22443

Query: 1549  QVTDVQDNSISVKWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQP 1604
             +V+ V   S  + W        + +T Y +    ++G    +   +   +T++ +  L  
Sbjct: 22444 EVSSVSAESCVLSWGEPKDGGGTEITNY-IVEKRESGTTAWQLVNSSVKRTQIKVTHLTK 22502

Query: 1605  TVEYVVSVYAQNPSGESQPLVQTAV------TNIDRPKGLAFTDVDVDSIKIAWESPQGQ 1658
              +EY   V ++N  G S+PL    +           P       V  +++ I WE P   
Sbjct: 22503 YMEYSFRVSSENRFGVSKPLESAPIIAEHPFVPPSAPTRPEVYHVSANAMSIRWEEPYHD 22562

Query: 1659  VSRYRVTYSSPEDGIHELFPAPDGE----EDTAELQGLRPGSEYTVSVVALH------DD 1708
                  + Y   +   + +    + +    E   ++ GL  G EY     AL+        
Sbjct: 22563 GGSKIIGYWVEKKERNTILWVKENKVPCLECNYKVTGLVEGLEYQFRTYALNAAGVSKAS 22622

Query: 1709  MESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPP----NVQLTGYRVRVTPKEKTGP 1764
               S+P++      + AP   + T VT +++S  W+ P      ++ GY +   P  + G 
Sbjct: 22623 EASRPIMA--QNPVDAPGRPEVTDVTRSTVSLIWSAPAYDGGSKVVGYIIERKPVSEVGD 22680

Query: 1765  ---MKEINLAPDSSSVVVSGLMVATKYEVSVYALKDT-LTSRPAQ--GVVTTLENVSPPR 1818
                +K        +   V+ L     YE  V A     + S+ ++  G VT  +  +PP+
Sbjct: 22681 GRWLKCNYTIVSDNFFTVTALSEGDTYEFRVLAKNAAGVISKGSESTGPVTCRDEYAPPK 22740

Query: 1819  RARVTDATETTITISWRTKTETITGFQVDAVP------ANGQTPIQRTIKPDV-----RS 1867
                  DA      ++ R  ++ +    V   P        G   +    K  +     R+
Sbjct: 22741 AE--LDARLHGDLVTIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRA 22798

Query: 1868  YTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAP---SNLRFLATTPNSLLVSWQ 1924
               +      +D   Y  T+  NA  +  V      +D+P     L     T     ++W 
Sbjct: 22799 TAVIKFCDRSDSGKYTLTVK-NASGTKAVSVMVKVLDSPGPCGKLTVSRVTQEKCTLAWS 22857

Query: 1925  PPR----ARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKN-- 1978
              P+    A IT YI++  +       +V    P ++   +T L    EY   V A+    
Sbjct: 22858 LPQEDGGAEITHYIVERRETSRLNWVIVEGECPTLS-YVVTRLIKNNEYIFRVRAVNKYG 22916

Query: 1979  ---NQKSEPLIGRKKTVQKTP 1996
                  +SEP++ R      +P
Sbjct: 22917 PGVPVESEPIVARNSFTIPSP 22937



 Score = 64.3 bits (155), Expect = 1e-09
 Identities = 115/519 (22%), Positives = 183/519 (35%), Gaps = 81/519 (15%)

Query: 1542  IDKPS---QMQVTDVQDNSISVKWLPSSSP----VTGYRVTTTP-KNGPGPTKTKTAGPD 1593
             +DKP     +++ DV  +  +V W P        +  Y +     K     T + T    
Sbjct: 11989 LDKPGPVRNLKIVDVSSDRCTVCWDPPEDDGGCEIQNYILEKCETKRMVWSTYSATVLTP 12048

Query: 1594  QTEMT--IEGLQPTVEYVVSVYAQN-----PSGESQPLV-QTAVTNIDRPKGLAFTDVDV 1645
              T +T  IEG     EY+  V A+N     P  ES+P++ +T      RP     T V  
Sbjct: 12049 GTTVTRLIEGN----EYIFRVRAENKIGTGPPTESKPVIAKTKYDKPGRPDPPEVTKVSK 12104

Query: 1646  DSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGE----EDTAELQGLRPGSEYTVS 1701
             + + + W  P+    +    Y   +   H     P  +    E   ++Q L P  EY   
Sbjct: 12105 EEMTVVWNPPEYDGGKSITGYFLEKKEKHSTRWVPVNKSAIPERRMKVQNLLPDHEYQFR 12164

Query: 1702  VVALHD------DMESQPLIGTQSTAIPAP-TDLKFTQVTPTSLSAQWTPP----NVQLT 1750
             V A ++       + S+P++       P P T+ +    T  S++  W  P       + 
Sbjct: 12165 VKAENEIGIGEPSLPSRPVVAKDPIEPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAPII 12224

Query: 1751  GYRVRVTPKEKTGP----MKEINLAPD--SSSVVVSGLMVATKYEVSVYALKDTLTSRPA 1804
             GY V + PK          K  N A         V+ L    +YE  V A       RPA
Sbjct: 12225 GYVVEMRPKIADASPDEGWKRCNAAAQLVRKEFTVTSLDENQEYEFRVCAQNQVGIGRPA 12284

Query: 1805  Q--GVVTTLENVSPPRRARVTDATETTIT-------------------ISWRTK--TETI 1841
             +    +   E + PP         +  I                    ++WR       +
Sbjct: 12285 ELKEAIKPKEILEPPEIDLDASMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVV 12344

Query: 1842  TGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDAST 1901
                QVD V       I  + + D   Y++T + P  +  +++     N R    V+D   
Sbjct: 12345 RKGQVDLVDTMAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFV-----NVR----VLDTPG 12395

Query: 1902  AIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREVVPRPRPGVTE 1957
              +   S+L+    T  S  VSW PP     +++T YI++  +        V  P    T 
Sbjct: 12396 PV---SDLKVSDVTKTSCHVSWAPPENDGGSQVTHYIVEKREADRKTWSTVT-PEVKKTS 12451

Query: 1958  ATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQKTP 1996
               +T L PG EY   V A+       P    K  +   P
Sbjct: 12452 FHVTNLVPGNEYYFRVTAVNEYGPGVPTDVPKPVLASDP 12490



 Score = 62.4 bits (150), Expect = 5e-09
 Identities = 182/847 (21%), Positives = 298/847 (35%), Gaps = 156/847 (18%)

Query: 1263 IIPAVPPPTDLRFTNIGPDTMRVTWAPPPS---IDLTNFLVRYSPVKNEEDVAELSISPS 1319
            +I    P  +L  T      + + W  P +     +  ++V    +K +  V     + S
Sbjct: 6781 VIDVPGPVRNLEVTETFDGEVSLAWEEPLTDGGSKIIGYVVERRDIKRKTWVLATDRAES 6840

Query: 1320 DNAVVLTNLLPGTEYVVSVSS-----VYEQHES-TPLRGRQKTGLDSPT-GIDFSDITAN 1372
                V      G EY+  VS+       E  E+  P+  R K  +  P   +  +D+   
Sbjct: 6841 CEFTVTGLQKGGVEYLFRVSARNRVGTGEPVETDNPVEARSKYDVPGPPLNVTITDVNRF 6900

Query: 1373 SFTVHWIAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSI 1428
              ++ W  P     A IT Y I    +          V     S T+T++  G EY   +
Sbjct: 6901 GVSLTWEPPEYDGGAEITNYVIELRDKTSIRWDTAMTVRAEDLSATVTDVVEGQEYSFRV 6960

Query: 1429 VALNGREESPLLIGQQSTVSDV------------PRDLEVVAATPTSLLISWDAP----A 1472
                 R ++ + +G+ S  +              P +L     T +S+ + W+ P     
Sbjct: 6961 -----RAQNRIGVGKPSAATPFVKVADPIERPSPPVNLTSSDQTQSSVQLKWEPPLKDGG 7015

Query: 1473 VTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSK 1532
              +  Y I   E G ++ ++       + T  ++GL+ G  Y   V A    G S  S  
Sbjct: 7016 SPILGYIIERCEEGKDNWIRCNMKLVPELTYKVTGLEKGNKYLYRVSAENKAGVSDPSEI 7075

Query: 1533 PISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSS--PVTGYRVTTTPKNGPGPTKTKTA 1590
               +       +P+ M ++  +D    +   P +   P TGY         P PT T   
Sbjct: 7076 LGPLTADDAFVEPT-MDLSAFKDGLEVIVPNPITILVPSTGY---------PRPTATWCF 7125

Query: 1591 GPDQTE----MTIEGLQPTVEYVVSVYAQNPSG----ESQPLVQTAVTNID--------R 1634
            G    E    + ++ L    E V+S   ++  G    + +  V+T    ID         
Sbjct: 7126 GDKVLETGDRVKMKTLSAYAELVISPSERSDKGIYTLKLENRVKTISGEIDVNVIARPSA 7185

Query: 1635 PKGLAFTDVDVDSIKIAWESPQ----GQVSRY--------RVTYSSPEDGIHEL-FPAPD 1681
            PK L F D+  DS+ + WE P       ++ Y        R T++   D + +L F  PD
Sbjct: 7186 PKELKFGDITKDSVHLTWEPPDDDGGSPLTGYVVEKREVSRKTWTKVMDFVTDLEFTVPD 7245

Query: 1682 GEEDTAELQGLRPGSEYTVSVVALHDDMESQPL-------IGTQSTAIPAPTDLKFTQVT 1734
                      L  G EY   V A +     +P        + T +T    P ++K+   T
Sbjct: 7246 ----------LVQGKEYLFKVCARNKCGPGEPAYVDEPVNMSTPATVPDPPENVKWRDRT 7295

Query: 1735 PTSLSAQWTPP----NVQLTGYRVRVTPKEKTGPMKEINLAPD--SSSVVVSGLMVATKY 1788
              S+   W PP      ++ GY V   P+   G  K +        + + V+GL     Y
Sbjct: 7296 ANSIFLTWDPPKNDGGSRIKGYIVERCPR---GSDKWVACGEPVAETKMEVTGLEEGKWY 7352

Query: 1789 EVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETT-----------ITISWRTK 1837
               V AL     S+P++          P    +  D  E             +T+   TK
Sbjct: 7353 AYRVKALNRQGASKPSR----------PTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTK 7402

Query: 1838 TE---TITGFQVDAVPANGQTPIQRTIKPDVR----------SYTITGLQPGTDYKIYLY 1884
             E   T+TG      P    T     +K D R          + TI   +        + 
Sbjct: 7403 IELPATVTG---KPEPKITWTKADMILKQDKRITIENVPKKSTVTIVDSKRSDTGTYIIE 7459

Query: 1885 TLNDNARSSPVV-IDASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEK 1939
             +N   R++ VV ++       P+       T  S L++W PPR    ++IT Y+++   
Sbjct: 7460 AVNVCGRATAVVEVNVLDKPGPPAAFDITDVTNESCLLTWNPPRDDGGSKITNYVVERRA 7519

Query: 1940 PGSPPREVVPRPRPGV--TEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQKTPF 1997
              S   EV  +    V  T    T L P  EY   V A       E + G  + VQ +P 
Sbjct: 7520 TDS---EVWHKLSSTVKDTNFKATKLIPNKEYIFRVAA-------ENMYGVGEPVQASPI 7569

Query: 1998 VTHPGYD 2004
                 +D
Sbjct: 7570 TAKYQFD 7576



 Score = 52.8 bits (125), Expect = 4e-06
 Identities = 80/336 (23%), Positives = 120/336 (35%), Gaps = 46/336 (13%)

Query: 602  LQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQP---SHISKYILRWRPKN-SVGRWKEA 657
            ++ Y   S P  + +T+  ++  S  + W+AP     S I+ Y++  R  +     W+E 
Sbjct: 9187 VEVYDRPSPPRNLAVTDIKAE--SCYLTWDAPLDNGGSEITHYVIDKRDASRKKAEWEEV 9244

Query: 658  TIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTP 717
            T       Y I  L P   YE ++ ++ +YG  +  + D         V  +       P
Sbjct: 9245 TNTAVEKRYGIWKLIPNGQYEFRVRAVNKYGISDECKSD-------KVVIQDPYRLPGPP 9297

Query: 718  FSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTA----- 772
              P V         T  S +VSW    D        Y L +  +   Y    S A     
Sbjct: 9298 GKPKVLAR------TKGSMLVSWTPPLDNGGSPITGYWLEKREEGSPYWSRVSRAPITKV 9351

Query: 773  ----TSVNIPDLLPGRKY-----IVNVYQISEDGEQSLILSTSQTTAPDAPPD-PTVDQV 822
                   N+P LL G KY      +N   I    E S          P  PP  P V   
Sbjct: 9352 GLKGVEFNVPRLLEGVKYQFRAMAINAAGIGPPSEPSDPEVAGDPIFPPGPPSCPEVKDK 9411

Query: 823  DDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPE---TANSVTLSDLQPGVQ 875
              +SI + W  P     +PI GY +            +N P+   T     + +L+   +
Sbjct: 9412 TKSSISLGWKPPAKDGGSPIKGYIVEMQEEGTTDWKRVNEPDKLITTCECVVPNLKELRK 9471

Query: 876  YNITIYAVEENQESTPVVIQQETTG-TPRSDTVPSP 910
            Y   + AV E  ES P     +TTG  P +D    P
Sbjct: 9472 YRFRVKAVNEAGESEP----SDTTGEIPATDIQEEP 9503



 Score = 43.9 bits (102), Expect = 0.002
 Identities = 50/204 (24%), Positives = 83/204 (40%), Gaps = 22/204 (10%)

Query: 717   PFSPLVATSESVTEITASSFVVSWVSASDT----VSGFRVEYELSEEGDEPQYLDLPSTA 772
             P  P+V     +  +  +S V+SW   +D     ++ + VE   ++EG E Q +    + 
Sbjct: 24421 PTGPIV-----IEALLKNSAVISWKPPADDGGSWITNYVVEKCEAKEGAEWQLVSSAISV 24475

Query: 773   TSVNIPDLLPGRKYIV-----NVYQISEDGE-QSLILSTSQTTAPDAPPDPTVDQVDDTS 826
             T+  I +L     Y       N + IS+  E  S+++  S    P AP  PT+  V   S
Sbjct: 24476 TTCRIVNLTENAGYYFRVSAQNTFGISDPLEVSSVVIIKSPFEKPGAPGKPTITAVTKDS 24535

Query: 827   IVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSV-TLSDLQPGVQYNITIY 881
              VV W  P     A I  Y +      +     +   E   +V ++ +L  G++Y   + 
Sbjct: 24536 CVVAWKPPASDGGAKIRNYYLEKREKKQNKWISVTTEEIRETVFSVKNLIEGLEYEFRVK 24595

Query: 882   AVEENQESTPVVIQQETTGTPRSD 905
                   ES    I +    TP+SD
Sbjct: 24596 CENLGGESEWSEISEPI--TPKSD 24617



 Score = 41.2 bits (95), Expect = 0.012
 Identities = 92/413 (22%), Positives = 157/413 (38%), Gaps = 51/413 (12%)

Query: 1285  VTWAPPPSID---LTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSV 1341
             ++W PP       +TN++V     K   +   +S + S     + NL     Y   VS+ 
Sbjct: 24437 ISWKPPADDGGSWITNYVVEKCEAKEGAEWQLVSSAISVTTCRIVNLTENAGYYFRVSAQ 24496

Query: 1342  YEQHESTPLRGRQKTGLDSPTGID-------FSDITANSFTVHWIAPRATITGYRIRHHP 1394
                  S PL       + SP            + +T +S  V W  P A+  G +IR++ 
Sbjct: 24497 NTFGISDPLEVSSVVIIKSPFEKPGAPGKPTITAVTKDSCVVAW-KPPASDGGAKIRNYY 24555

Query: 1395  EHFSGRPREDRVPHSRNSITLT-----NLTPGTEYVVSIVA--LNGREESPLLIGQQSTV 1447
                  + +   +  +   I  T     NL  G EY   +    L G  E   +    +  
Sbjct: 24556 LEKREKKQNKWISVTTEEIRETVFSVKNLIEGLEYEFRVKCENLGGESEWSEISEPITPK 24615

Query: 1448  SDVP----------RDLEVVAATPTSLLISWDA-PAVTVRYYRITYGET----GGNSPVQ 1492
             SDVP          R+L V   +  +L+      P   V++YR   G+     G    +Q
Sbjct: 24616 SDVPIQAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYR--QGKEIIADGLKYRIQ 24673

Query: 1493  EFTVPGSKSTATISGLKPGVDYTITVYAV--TGRGDSPASSKPISINYRTEIDKPSQMQ- 1549
             EF   G      I+ +    D   TVY V  T +G S + +  + +    +I  P  ++ 
Sbjct: 24674 EFK--GGYHQLIIASV---TDDDATVYQVRATNQGGSVSGTASLEVEVPAKIHLPKTLEG 24728

Query: 1550  ---VTDVQDNSISVKWLPSSS---PVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQ 1603
                V  ++   +S+K +P S    PV  ++      +  G  +        + +   G++
Sbjct: 24729 MGAVHALRGEVVSIK-IPFSGKPDPVITWQKGQDLIDNNGHYQVIVTRSFTSLVFPNGVE 24787

Query: 1604  PTVEYVVSVYAQNPSGESQPLVQTAVTNI-DRPKGLAFTDVDVDSIKIAWESP 1655
                     V A+N  G  Q  V+  V ++ D P+G+  +DV  DS+ + W  P
Sbjct: 24788 RKDAGFYVVCAKNRFGIDQKTVELDVADVPDPPRGVKVSDVSRDSVNLTWTEP 24840



 Score = 37.7 bits (86), Expect = 0.13
 Identities = 36/131 (27%), Positives = 53/131 (40%), Gaps = 8/131 (6%)

Query: 894   IQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPVNLPGE 949
             I Q+T     +D    PR ++  +V+   V + WT P     S +T Y V+        E
Sbjct: 24804 IDQKTVELDVADVPDPPRGVKVSDVSRDSVNLTWTEPASDGGSKITNYIVEKCATT--AE 24861

Query: 950   HGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQ--TTKLDAPTNLQFVN 1007
                R+  +R T   V  L    +Y F+V A +    SKP    +   TK D    + +  
Sbjct: 24862 RWLRVGQARETRYTVINLFGKTSYQFRVIAENKFGLSKPSEPSEPTITKEDKTRAMNYDE 24921

Query: 1008  ETDSTVLVRWT 1018
             E D T  V  T
Sbjct: 24922 EVDETREVSMT 24932



 Score = 35.0 bits (79), Expect = 0.86
 Identities = 38/169 (22%), Positives = 71/169 (42%), Gaps = 17/169 (10%)

Query: 1519  YAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWL-PSS---SPVTGYRV 1574
             Y V  +       K + ++     D P  ++V+DV  +S+++ W  P+S   S +T Y V
Sbjct: 24794 YVVCAKNRFGIDQKTVELDVADVPDPPRGVKVSDVSRDSVNLTWTEPASDGGSKITNYIV 24853

Query: 1575  TTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPL--VQTAVTNI 1632
                        +   A   +T  T+  L     Y   V A+N  G S+P    +  +T  
Sbjct: 24854 EKCATTAERWLRVGQA--RETRYTVINLFGKTSYQFRVIAENKFGLSKPSEPSEPTITKE 24911

Query: 1633  DRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPD 1681
             D+ + + + D +VD  +        +VS  + ++SS ++   +   A D
Sbjct: 24912 DKTRAMNY-DEEVDETR--------EVSMTKASHSSTKELYEKYMIAED 24951


>gi|110349713 titin isoform novex-1 [Homo sapiens]
          Length = 27051

 Score =  154 bits (388), Expect = 1e-36
 Identities = 299/1365 (21%), Positives = 509/1365 (37%), Gaps = 169/1365 (12%)

Query: 590   YGRGIGEWHCQPLQTYPSSSGPVEVFITETPSQPNSHPI-QWNAPQP---SHISKYILRW 645
             YG G+     +P+    S + P    I E       H I QW  P+    + IS Y++  
Sbjct: 22848 YGPGVPV-ESEPIVARNSFTIPSPPGIPEEVGTGKEHIIIQWTKPESDGGNEISNYLVDK 22906

Query: 646   RPKNSVGRWKEATIPGHLNSYTIK--GLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTS 703
             R K S+ RW        +    +K   L  G  Y+ ++ ++   G+ E +          
Sbjct: 22907 REKKSL-RWTRVNKDYVVYDTRLKVTSLMEGCDYQFRVTAVNAAGNSEPSE--------- 22956

Query: 704   TPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELS-EEGDE 762
                 SN ++     ++P   ++  V + T  S  ++W           V Y L  +E D 
Sbjct: 22957 ---ASNFISCREPSYTPGPPSAPRVVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDT 23013

Query: 763   PQYLDLPSTATSVN----IPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPT 818
              Q+  + + AT  N    +PDL  G+KY   V  ++  G      S ++    +    P 
Sbjct: 23014 DQWYRVHTNATIRNTEFTVPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEIPD 23073

Query: 819   VDQVDDT--SIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLP-----ETANSVTLSDLQ 871
             ++  DD   ++ +R       +        P +  S   ++L      +T  S +L  + 
Sbjct: 23074 LELADDLKKTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAIIDTTESYSLLIVD 23133

Query: 872   PGVQYNITIYAVE-ENQE----STPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIM 926
                +Y+   Y +E ENQ     +T +V   +T G       P P  ++  EV+   VTI 
Sbjct: 23134 KVNRYDAGKYTIEAENQSGKKSATVLVKVYDTPG-------PCP-SVKVKEVSRDSVTIT 23185

Query: 927   WTPPE----SAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSH 982
             W  P     + V  Y V+     +          S+ T   ++GL  G  YYF+V   + 
Sbjct: 23186 WEIPTIDGGAPVNNYIVEKREAAMRAFKTVTTKCSK-TLYRISGLVEGTMYYFRVLPENI 23244

Query: 983   GRESKPLTAQQTTKLD----APTNLQFVNETDSTVLVRWTPPR----AQITGYRLTVGLT 1034
                 +P        +      P  L+ V+ T STV + W  P     +++TGY L     
Sbjct: 23245 YGIGEPCETSDAVLVSEVPLVPAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEA--C 23302

Query: 1035  RRGQPRQYNV---GPSVSKYPLRNLQPASEYTVSLVAI--KGNQESPKATGVFTTLQPGS 1089
             + G  R   V    P+V ++ + +L    +Y   + A   KG  E P+ T    T+Q   
Sbjct: 23303 KAGTERWMKVVTLKPTVLEHTVTSLNEGEQYLFRIRAQNEKGVSE-PRETVTAVTVQDLR 23361

Query: 1090  SIPPYNTEV-------------TETTIVITWTPAPRIG-FKLGVRPSQGGEAPREVTSDS 1135
              +P  +                 E  I I   P P    F  G +  +      E  +  
Sbjct: 23362 VLPTIDLSTMPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKV 23421

Query: 1136  GSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSW 1195
               + +   T      YT+++          I   ++    PPT        D   +T+SW
Sbjct: 23422 AKLTIRETTIRDTGEYTLELKNVTGTTSETIKVIILDKPGPPTGPIKIDEIDATSITISW 23481

Query: 1196  ERSTTPD---ITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSV----- 1247
             E         ++GY +     +      + E V   +S+  F  L+ G EY   V     
Sbjct: 23482 EPPELDGGAPLSGYVVEQRDAHRPGWLPVSESV--TRSTFKFTRLTEGNEYVFRVAATNR 23539

Query: 1248  YTVKDDKESVPISDTIIPAVP-PPTDLRFTNIGPDTMRVTWAPPPS---IDLTNFLVRYS 1303
             + +    +S  I       +P PP  L+  ++  D M +TW PP       +T ++V   
Sbjct: 23540 FGIGSYLQSEVIECRSSIRIPGPPETLQIFDVSRDGMTLTWYPPEDDGGSQVTGYIVERK 23599

Query: 1304  PVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLR-GRQKTGLD--- 1359
              V+ +  V    +  +      T L  G EY   V+++  +    P R  +    +D   
Sbjct: 23600 EVRADRWVRVNKVPVTMTRYRSTGLTEGLEYEHRVTAINARGSGKPSRPSKPIVAMDPIA 23659

Query: 1360  ---SPTGIDFSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRNS 1412
                 P     +D T  S ++ W  P     + +TGY I           + +  P     
Sbjct: 23660 PPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTKCNTTPTKIRE 23719

Query: 1413  ITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAAT--PTSLLISWDA 1470
              TLT+L  G EY   ++A N         G     ++VP  ++V      P   L     
Sbjct: 23720 YTLTHLPQGAEYRFRVLACNA--------GGPGEPAEVPGTVKVTEMLEYPDYELDERYQ 23771

Query: 1471  PAVTVRY---YRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDS 1527
               + VR     R+T    G   P+ ++T  G +  +  + +     +T  V     RGDS
Sbjct: 23772 EGIFVRQGGVIRLTIPIKGKPFPICKWTKEG-QDISKRAMIATSETHTELVIKEADRGDS 23830

Query: 1528  ---------PASSKPISINYRTEIDKPSQ----MQVTDVQDNSISVKWLPSS----SPVT 1570
                          K + I  R  I  P+     ++  D+Q  S+ V W P +    + + 
Sbjct: 23831 GTYDLVLENKCGKKAVYIKVRV-IGSPNSPEGPLEYDDIQVRSVRVSWRPPADDGGADIL 23889

Query: 1571  GYRVTT--TPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQ-- 1626
             GY +     PK       ++  G   T + ++GL+  VEY   V A+N  G S+PL    
Sbjct: 23890 GYILERREVPKAAWYTIDSRVRG---TSLVVKGLKENVEYHFRVSAENQFGISKPLKSEE 23946

Query: 1627  --TAVTNIDRPKGLA----FTDVDVDSIKIAWESPQGQ-VSRYRVTYSSPEDGIHELFPA 1679
               T  T ++ P+  +      DV   S+ ++W  P+    SR    Y   ++   + +  
Sbjct: 23947 PVTPKTPLNPPEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRVTGYYIERKETSTDKWVR 24006

Query: 1680  PDGEEDTAEL---QGLRPGSEYTVSVVALHD------DMESQPLIGTQSTAIPA-PTDLK 1729
              +  + T  +    GL P +EY   ++A +D         S+P++       P+ P +L+
Sbjct: 24007 HNKTQITTTMYTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCKDPFDKPSQPGELE 24066

Query: 1730  FTQVTPTSLSAQWTPPNV----QLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVA 1785
                ++  S++ QW  P      ++ GY V       +   K            + GL+ A
Sbjct: 24067 ILSISKDSVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERIKDKQFTIGGLLEA 24126

Query: 1786  TKYEVSVYALKDTLTSRP---AQGVVTTL-ENVSPPRRARVTDAT 1826
             T+YE  V+A  +T  SRP   A  + T L    +P  R  + D T
Sbjct: 24127 TEYEFRVFAENETGLSRPRRTAMSIKTKLTSGEAPGIRKEMKDVT 24171



 Score =  148 bits (373), Expect = 7e-35
 Identities = 289/1429 (20%), Positives = 524/1429 (36%), Gaps = 170/1429 (11%)

Query: 696   DFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYE 755
             D+T T+ ++  + +          P    S  + ++ +   ++SW    +        Y 
Sbjct: 12993 DYTITAENSSGSKSATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYI 13052

Query: 756   LSE-EGDEPQYLDLPSTA--TSVNIPDLLPGRKY-----IVNVYQISEDGEQSLILSTSQ 807
             + + E   P +  + +T   TS ++  L+ G +Y       N Y + +       ++ + 
Sbjct: 13053 VDKRETSRPNWAQVSATVPITSCSVEKLIEGHEYQFRICAENKYGVGDPVFTEPAIAKNP 13112

Query: 808   TTAPDAPPDPTVDQVDDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNL-PETA 862
                P     P +  +    + V W  P     +PITGY +    +   + T++N  P   
Sbjct: 13113 YDPPGRCDPPVISNITKDHMTVSWKPPADDGGSPITGYLLEKRETQAVNWTKVNRKPIIE 13172

Query: 863   NSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVK 922
              ++  + LQ G +Y   + A+ +     P    +             P   +  + T   
Sbjct: 13173 RTLKATGLQEGTEYEFRVTAINKAGPGKPSDASKAAYARDPQYPPGPPAFPKVYDTTRSS 13232

Query: 923   VTIMWTPPE----SAVTGYRVDVIPVNLPGEHGQRLPIS-RNTFAEVTGLSPGVTYYFKV 977
             V++ W  P     S + GY V+V   +        LP + + T  EVTGL     Y F+V
Sbjct: 13233 VSLSWGKPAYDGGSPIIGYLVEVKRADSDNWVRCNLPQNLQKTRFEVTGLMEDTQYQFRV 13292

Query: 978   FAVSHGRESKP-----------LTAQQTTKLDAPTNLQFVNETDST----VLVRWTPPRA 1022
             +AV+    S P           +      +LDA      +     T    V V+  PP  
Sbjct: 13293 YAVNKIGYSDPSDVPDKHYPKDILIPPEGELDADLRKTLILRAGVTMRLYVPVKGRPP-P 13351

Query: 1023  QITGYRLTVGLTRR-GQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGV 1081
             +IT  +  V L  R G   +     +  +    N   A +Y ++L    G +E      V
Sbjct: 13352 KITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKYILTLENSCGKKEYTIVVKV 13411

Query: 1082  FTTLQPGSSIPPYNTEVTETTIVITWTP------APRIGFKLGVRPSQGGEAPREVTSDS 1135
               T  PG  +     E+++ +  +TW P      +P I + +  R ++        T  S
Sbjct: 13412 LDT--PGPPVNVTVKEISKDSAYVTWEPPIIDGGSPIINYVVQKRDAERKSWSTVTTECS 13469

Query: 1136  G-SIVVSGLTPGVEYVYTIQVLRD------GQERDAPIVNKVVTPLSPPTNLHLEANPDT 1188
               S  V+ L  G  Y + +    +      G+ RDA  V    TP  P  +L + +   +
Sbjct: 13470 KTSFRVANLEEGKSYFFRVFAENEYGIGDPGETRDA--VKASQTP-GPVVDLKVRSVSKS 13526

Query: 1189  GVLTVSWERSTTPD---ITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNV 1245
                ++ W++  +     I GY +        + N  + V+ +     +  +L+ G EY  
Sbjct: 13527 SC-SIGWKKPHSDGGSRIIGYVVDFLT----EENKWQRVMKSLSLQYSAKDLTEGKEYTF 13581

Query: 1246  SVYTVKDDKESVPISDTIIP---AVPPPTDLRFTNIGPDT-------------MRVTWAP 1289
              V    ++ E  P   T++     V P  DL+     PD              + +   P
Sbjct: 13582 RVSAENENGEGTPSEITVVARDDVVAPDLDLKGL---PDLCYLAKENSNFRLKIPIKGKP 13638

Query: 1290  PPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLL-------PGTEYVVSVSSVY 1342
              PS+         S  K E+ +A  +    +++ V T L+          +Y +++ +V 
Sbjct: 13639 APSV---------SWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVA 13689

Query: 1343  EQHEST-PLRGRQKTGLDSPTG-IDFSDITANSFTVHWIAPR----ATITGYRIRHHPEH 1396
                E T  ++   K G+  PTG I F ++TA + T+ W  P+    + IT Y I    + 
Sbjct: 13690 GTKEGTISIKVVGKPGI--PTGPIKFDEVTAEAMTLKWAPPKDDGGSEITNY-ILEKRDS 13746

Query: 1397  FSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN------GREESPLLIGQQSTVSDV 1450
              + +         + +  +T L  G EY   + A N      G +  P++      V D 
Sbjct: 13747 VNNKWVTCASAVQKTTFRVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVPDA 13806

Query: 1451  PRDLEVVAATPTSLLISWDAPAVT----VRYYRITYGETGGNSPVQEFTVPGSKSTATIS 1506
             P    +V     S+ ++W  P  T    +  Y + + E       +    P       ++
Sbjct: 13807 PPPPNIVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTPIRMRDFKVT 13866

Query: 1507  GLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLP-- 1564
             GL  G++Y   V A+   G    S     +     ID P + +V ++  NS+++ W    
Sbjct: 13867 GLTEGLEYEFRVMAINLAGVGKPSLPSEPVVALDPIDPPGKPEVINITRNSVTLIWTEPK 13926

Query: 1565  --SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQ 1622
                   +TGY V           K       +   T+  L    +Y   + A+N +G   
Sbjct: 13927 YDGGHKLTGYIVEKRDLPSKSWMKANHVNVPECAFTVTDLVEGGKYEFRIRAKNTAGAIS 13986

Query: 1623  PLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQV----------------SRYRVTY 1666
                ++  T I + +  A T V   +IK       G                  S  +   
Sbjct: 13987 APSESTETIICKDEYEAPTIVLDPTIKDGLTIKAGDTIVLNAISILGKPLPKSSWSKAGK 14046

Query: 1667  SSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPT 1726
                   I ++   P     T +    +   EYT++             +       P P 
Sbjct: 14047 DIRPSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFGTKVEHVKVTVLDVPGP-PG 14105

Query: 1727  DLKFTQVTPTSLSAQWTPPNVQLTGYRVR--VTPKEKTGPMKEINLAPDSSSV--VVSGL 1782
              ++ + V+    +  WTPP ++  G  ++  +  K +T  +    ++ D  S   V + L
Sbjct: 14106 PVEISNVSAEKATLTWTPP-LEDGGSPIKSYILEKRETSRLLWTVVSEDIQSCRHVATKL 14164

Query: 1783  MVATKYEVSVYALKDTLTSRPAQG----VVTTLENVSPPRRARVTDATETTITISWRTKT 1838
             +   +Y   V A+       P Q     +V       PP +  V++ T+ T T+SW+   
Sbjct: 14165 IQGNEYIFRVSAVNHYGKGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSWKRPV 14224

Query: 1839  E----TITGFQVDAVPANGQTPIQRTIKPDVRSY--TITGLQPGTDYKIYLYTLN----- 1887
             +     ITG+ V+         + R IK  V      +TGLQ G+ Y+  +   N     
Sbjct: 14225 DDGGSEITGYHVERREKKSLRWV-RAIKTPVSDLRCKVTGLQEGSTYEFRVSAENRAGIG 14283

Query: 1888  --DNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPG 1941
                 A  S ++ DA+     PSN     TT  S  ++W  P       ITGY+++++K G
Sbjct: 14284 PPSEASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLAWGKPHYDGGLEITGYVVEHQKVG 14343

Query: 1942  SPPREVVPRPRPG----VTEATITGLEPGTEYTIYVIALKNNQKSEPLI 1986
                 E   +   G    +T+  +  L+   +Y   + A+ +    EP +
Sbjct: 14344 D---EAWIKDTTGTALRITQFVVPDLQTKEKYNFRISAINDAGVGEPAV 14389



 Score =  146 bits (368), Expect = 3e-34
 Identities = 299/1392 (21%), Positives = 517/1392 (37%), Gaps = 202/1392 (14%)

Query: 780   LLPGRKYIVNVYQISEDG-----EQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRP 834
             L+   +YI  V  +++ G     E   I++ +  T P  P  P         I+++W++P
Sbjct: 22832 LIKNNEYIFRVRAVNKYGPGVPVESEPIVARNSFTIPSPPGIPEEVGTGKEHIIIQWTKP 22891

Query: 835   QAP----ITGYRIVYSPSVEGSSTELNLPETANSVTL--SDLQPGVQYNITIYAVEENQE 888
             ++     I+ Y +          T +N         L  + L  G  Y   + AV     
Sbjct: 22892 ESDGGNEISNYLVDKREKKSLRWTRVNKDYVVYDTRLKVTSLMEGCDYQFRVTAVNAAGN 22951

Query: 889   STPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPV 944
             S P       +    S T   P   + V+ T   +++ WT P     + + GY +++   
Sbjct: 22952 SEPSEASNFISCREPSYTPGPPSAPRVVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEK 23011

Query: 945   NLPGEHGQRLPIS-RNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTA----QQTTKLDA 999
             +    +      + RNT   V  L  G  Y F+V AV+    S+   +    +   +++ 
Sbjct: 23012 DTDQWYRVHTNATIRNTEFTVPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEI 23071

Query: 1000  PTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQP-----------RQYNVGPSV 1048
             P +L+  ++   TV +R           RL V ++ R  P               +  + 
Sbjct: 23072 P-DLELADDLKKTVTIRAG------ASLRLMVSVSGRPPPVITWSKQGIDLASRAIIDTT 23124

Query: 1049  SKYPLR-----NLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTI 1103
               Y L      N   A +YT+      G + +     V+ T  P  S+     EV+  ++
Sbjct: 23125 ESYSLLIVDKVNRYDAGKYTIEAENQSGKKSATVLVKVYDTPGPCPSVKV--KEVSRDSV 23182

Query: 1104  VITWT------PAPRIGFKLGVRPSQGGEAPREVTSDSGSIV-VSGLTPGVEYVYTIQ-- 1154
              ITW        AP   + +  R +         T  S ++  +SGL  G  Y + +   
Sbjct: 23183 TITWEIPTIDGGAPVNNYIVEKREAAMRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPE 23242

Query: 1155  ----VLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPD---ITGYR 1207
                 +    +  DA +V++V  PL P     ++    T  +T++WE+        +TGY 
Sbjct: 23243 NIYGIGEPCETSDAVLVSEV--PLVPAKLEVVDVTKST--VTLAWEKPLYDGGSRLTGYV 23298

Query: 1208  ITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEY-----------------NVSVYTV 1250
             +       ++   +   +       T  +L+ G +Y                  V+  TV
Sbjct: 23299 LEACKAGTERWMKVV-TLKPTVLEHTVTSLNEGEQYLFRIRAQNEKGVSEPRETVTAVTV 23357

Query: 1251  KD-------DKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYS 1303
             +D       D  ++P     +PA   P +L         + +   PPP+     F     
Sbjct: 23358 QDLRVLPTIDLSTMPQKTIHVPA-GRPVEL--------VIPIAGRPPPAASW--FFAGSK 23406

Query: 1304  PVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVY-EQHESTPLRGRQKTGLDSPT 1362
               ++E    E     +   +  T +    EY + + +V     E+  +    K G   PT
Sbjct: 23407 LRESERVTVETHTKVAKLTIRETTIRDTGEYTLELKNVTGTTSETIKVIILDKPG--PPT 23464

Query: 1363  G-IDFSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSG-RPREDRVPHSRNSITLT 1416
             G I   +I A S T+ W  P     A ++GY +     H  G  P  + V  +R++   T
Sbjct: 23465 GPIKIDEIDATSITISWEPPELDGGAPLSGYVVEQRDAHRPGWLPVSESV--TRSTFKFT 23522

Query: 1417  NLTPGTEYVVSIVALN----GREESPLLIGQQSTVS--DVPRDLEVVAATPTSLLISWDA 1470
              LT G EYV  + A N    G      +I  +S++     P  L++   +   + ++W  
Sbjct: 23523 RLTEGNEYVFRVAATNRFGIGSYLQSEVIECRSSIRIPGPPETLQIFDVSRDGMTLTWYP 23582

Query: 1471  P----AVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGD 1526
             P       V  Y +   E   +  V+   VP + +    +GL  G++Y   V A+  RG 
Sbjct: 23583 PEDDGGSQVTGYIVERKEVRADRWVRVNKVPVTMTRYRSTGLTEGLEYEHRVTAINARGS 23642

Query: 1527  SPAS--SKPI-SINYRTEIDKPSQMQVTDVQDNSISVKWL----PSSSPVTGYRVTTTPK 1579
                S  SKPI +++      KP   +VTD    S+S+ W        S VTGY +     
Sbjct: 23643 GKPSRPSKPIVAMDPIAPPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKV 23702

Query: 1580  NGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLA 1639
             +    TK  T      E T+  L    EY   V A N  G  +P        +     L 
Sbjct: 23703 DQHEWTKCNTTPTKIREYTLTHLPQGAEYRFRVLACNAGGPGEPAEVPGTVKVTEM--LE 23760

Query: 1640  FTDVDVDS-IKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEY 1698
             + D ++D   +      QG V R  +        I +     +G+ D ++   +     +
Sbjct: 23761 YPDYELDERYQEGIFVRQGGVIRLTIPIKGKPFPICKW--TKEGQ-DISKRAMIATSETH 23817

Query: 1699  TVSVVALHDDMES------------QPLIGTQSTAIPAPTD----LKFTQVTPTSLSAQW 1742
             T  V+   D  +S            +  +  +   I +P      L++  +   S+   W
Sbjct: 23818 TELVIKEADRGDSGTYDLVLENKCGKKAVYIKVRVIGSPNSPEGPLEYDDIQVRSVRVSW 23877

Query: 1743  TPP----NVQLTGYRV--RVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALK 1796
              PP       + GY +  R  PK        I+     +S+VV GL    +Y   V A  
Sbjct: 23878 RPPADDGGADILGYILERREVPK---AAWYTIDSRVRGTSLVVKGLKENVEYHFRVSAEN 23934

Query: 1797  DTLTSRP--AQGVVTTLENVSPPRRA----RVTDATETTITISW-RTKTE---TITGFQV 1846
                 S+P  ++  VT    ++PP        V D T++++++SW R K +    +TG+ +
Sbjct: 23935 QFGISKPLKSEEPVTPKTPLNPPEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRVTGYYI 23994

Query: 1847  DAVPANGQTPIQRTIKPDVRS--YTITGLQPGTDYKIYLYTLND------NARSSPVVI- 1897
             +    +    ++   K  + +  YT+TGL P  +Y+  +   ND      +  S PVV  
Sbjct: 23995 ERKETSTDKWVRHN-KTQITTTMYTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCK 24053

Query: 1898  DASTAIDAPSNLRFLATTPNSLLVSWQPPRA----RITGYIIKYEKPGSPPREVVPRPRP 1953
             D       P  L  L+ + +S+ + W+ P       I GY ++Y + G    +   + R 
Sbjct: 24054 DPFDKPSQPGELEILSISKDSVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERI 24113

Query: 1954  GVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQKTPFVTHPGYDTGNGIQLPG 2013
                + TI GL   TEY   V A      S P                    T   I+   
Sbjct: 24114 KDKQFTIGGLLEATEYEFRVFAENETGLSRP------------------RRTAMSIKTKL 24155

Query: 2014  TSGQQPSVGQQM 2025
             TSG+ P + ++M
Sbjct: 24156 TSGEAPGIRKEM 24167



 Score =  134 bits (338), Expect = 8e-31
 Identities = 286/1432 (19%), Positives = 516/1432 (36%), Gaps = 199/1432 (13%)

Query: 728   VTEITASSFVVSWVSASDTVSGFRVEY--ELSEEGDEP-QYLDLPSTATSVNIPDLLPGR 784
             V+ ++A S V+SW    D        Y  E  E G    Q ++     T + +  L    
Sbjct: 22378 VSSVSAESCVLSWGEPKDGGGTEITNYIVEKRESGTTAWQLVNSSVKRTQIKVTHLTKYM 22437

Query: 785   KYIVNV-----YQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPIT 839
             +Y   V     + +S+  E + I++      P AP  P V  V   ++ +RW  P     
Sbjct: 22438 EYSFRVSSENRFGVSKPLESAPIIAEHPFVPPSAPTRPEVYHVSANAMSIRWEEPYHDGG 22497

Query: 840   GYRIVYSPSVEGSST-----ELNLPETANSVTLSDLQPGVQYNITIYAV------EENQE 888
                I Y    +  +T     E  +P    +  ++ L  G++Y    YA+      + ++ 
Sbjct: 22498 SKIIGYWVEKKERNTILWVKENKVPCLECNYKVTGLVEGLEYQFRTYALNAAGVSKASEA 22557

Query: 889   STPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPV 944
             S P++ Q         + V +P   +  +VT   V+++W+ P     S V GY ++  PV
Sbjct: 22558 SRPIMAQ---------NPVDAPGRPEVTDVTRSTVSLIWSAPAYDGGSKVVGYIIERKPV 22608

Query: 945   NLPGEHGQRLP----ISRNTFAEVTGLSPGVTYYFKVFA------VSHGRESK-PLT--- 990
             +  G+ G+ L     I  + F  VT LS G TY F+V A      +S G ES  P+T   
Sbjct: 22609 SEVGD-GRWLKCNYTIVSDNFFTVTALSEGDTYEFRVLAKNAAGVISKGSESTGPVTCRD 22667

Query: 991   --AQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPR-------- 1040
               A    +LDA  +   V     + LV      A + G      +  +G           
Sbjct: 22668 EYAPPKAELDARLHGDLVTIRAGSDLVL----DAAVGGKPEPKIIWTKGDKELDLCEKVS 22723

Query: 1041  -QYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTL--QPGSSIPPYNTE 1097
              QY    + +     +   + +YT+++     N    KA  V   +   PG       + 
Sbjct: 22724 LQYTGKRATAVIKFCDRSDSGKYTLTVK----NASGTKAVSVMVKVLDSPGPCGKLTVSR 22779

Query: 1098  VTETTIVITWTPAPRIGFKLGVRPSQGGEAP-------REVTSDSGSIVVSGLTPGVEYV 1150
             VT+    + W+            P + G A        R  TS    ++V G  P + YV
Sbjct: 22780 VTQEKCTLAWS-----------LPQEDGGAEITHYIVERRETSRLNWVIVEGECPTLSYV 22828

Query: 1151  YTIQVLRDGQE----------------RDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVS 1194
              T +++++ +                    PIV +    +  P  +  E       + + 
Sbjct: 22829 VT-RLIKNNEYIFRVRAVNKYGPGVPVESEPIVARNSFTIPSPPGIPEEVGTGKEHIIIQ 22887

Query: 1195  WERSTTP---DITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVK 1251
             W +  +    +I+ Y +        +   + +      +     +L  G +Y   V  V 
Sbjct: 22888 WTKPESDGGNEISNYLVDKREKKSLRWTRVNKDYVVYDTRLKVTSLMEGCDYQFRVTAVN 22947

Query: 1252  DDKESVP--ISDTIIPAVP-----PPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSP 1304
                 S P   S+ I    P     PP+  R  +    ++ + W  P   D    +V Y  
Sbjct: 22948 AAGNSEPSEASNFISCREPSYTPGPPSAPRVVDTTKHSISLAWTKP-MYDGGTDIVGYVL 23006

Query: 1305  VKNEEDVAE-----LSISPSDNAVVLTNLLPGTEYVVSVSSV----YEQHESTPLRGRQK 1355
                E+D  +      + +  +    + +L  G +Y   V++V      ++  +       
Sbjct: 23007 EMQEKDTDQWYRVHTNATIRNTEFTVPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPV 23066

Query: 1356  TGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVP-------- 1407
               ++ P  ++ +D    + T+   A    +     R  P     +   D           
Sbjct: 23067 ERIEIPD-LELADDLKKTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAIIDTTE 23125

Query: 1408  -HSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLI 1466
              +S   +   N     +Y +     +G++ + +L+    T    P  ++V   +  S+ I
Sbjct: 23126 SYSLLIVDKVNRYDAGKYTIEAENQSGKKSATVLVKVYDTPGPCP-SVKVKEVSRDSVTI 23184

Query: 1467  SWDAPAVT----VRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYA-- 1520
             +W+ P +     V  Y +   E    +  +  T   SK+   ISGL  G  Y   V    
Sbjct: 23185 TWEIPTIDGGAPVNNYIVEKREAAMRA-FKTVTTKCSKTLYRISGLVEGTMYYFRVLPEN 23243

Query: 1521  VTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKW----LPSSSPVTGYRVTT 1576
             + G G+   +S  + ++    +  P++++V DV  +++++ W        S +TGY +  
Sbjct: 23244 IYGIGEPCETSDAVLVSEVPLV--PAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEA 23301

Query: 1577  TPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPK 1636
                      K  T  P   E T+  L    +Y+  + AQN  G S+P        +   +
Sbjct: 23302 CKAGTERWMKVVTLKPTVLEHTVTSLNEGEQYLFRIRAQNEKGVSEPRETVTAVTVQDLR 23361

Query: 1637  GLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDG--EEDTAELQGLRP 1694
              L   D+     K     P G+     +  +         F A     E +   ++    
Sbjct: 23362 VLPTIDLSTMPQKTI-HVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTK 23420

Query: 1695  GSEYTVSVVALHDD----MESQPLIGTQSTAI---------PAPTDLKFTQVTPTSLSAQ 1741
              ++ T+    + D     +E + + GT S  I         P    +K  ++  TS++  
Sbjct: 23421 VAKLTIRETTIRDTGEYTLELKNVTGTTSETIKVIILDKPGPPTGPIKIDEIDATSITIS 23480

Query: 1742  WTPPNVQ----LTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKD 1797
             W PP +     L+GY V      + G +      P S SV  S        E + Y  + 
Sbjct: 23481 WEPPELDGGAPLSGYVVEQRDAHRPGWL------PVSESVTRSTFKFTRLTEGNEYVFRV 23534

Query: 1798  TLTSRPAQGVVTTLENVS---------PPRRARVTDATETTITISWRTKTET----ITGF 1844
               T+R   G     E +          PP   ++ D +   +T++W    +     +TG+
Sbjct: 23535 AATNRFGIGSYLQSEVIECRSSIRIPGPPETLQIFDVSRDGMTLTWYPPEDDGGSQVTGY 23594

Query: 1845  QVDAVPANGQTPIQRTIKP-DVRSYTITGLQPGTDYKIYLYTLNDNARSSP-------VV 1896
              V+         ++    P  +  Y  TGL  G +Y+  +  +N      P       V 
Sbjct: 23595 IVERKEVRADRWVRVNKVPVTMTRYRSTGLTEGLEYEHRVTAINARGSGKPSRPSKPIVA 23654

Query: 1897  IDASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREVVPRPR 1952
             +D       P N R   TT  S+ ++W  P     +++TGY+I+ +K             
Sbjct: 23655 MDPIAPPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTKCNTTP 23714

Query: 1953  PGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQKTPFVTHPGYD 2004
               + E T+T L  G EY   V+A       EP      TV+ T  + +P Y+
Sbjct: 23715 TKIREYTLTHLPQGAEYRFRVLACNAGGPGEP-AEVPGTVKVTEMLEYPDYE 23765



 Score =  132 bits (333), Expect = 3e-30
 Identities = 291/1351 (21%), Positives = 478/1351 (35%), Gaps = 186/1351 (13%)

Query: 771   TATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVR 830
             T  S++  D     KYI+ +   S  G +S  ++      P  P +  V +V   S  + 
Sbjct: 17706 TQLSIDNCDRNDAGKYILKLENSS--GSKSAFVTVKVLDTPGPPQNLAVKEVRKDSAFLV 17763

Query: 831   WSRP----QAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEEN 886
             W  P     A +  Y I    S   +   ++   +  S  + +L  G  Y   + A  E 
Sbjct: 17764 WEPPIIDGGAKVKNYVIDKRESTRKAYANVSSKCSKTSFKVENLTEGAIYYFRVMAENEF 17823

Query: 887   QESTPVVIQQETTGTPRSDTVPSPRD-LQFVEVTDVKVTIMWTPPE----SAVTGYRVDV 941
                 PV    ET    ++   PSP   +   +V+    ++MW  PE    S V GY V++
Sbjct: 17824 GVGVPV----ETVDAVKAAEPPSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVEM 17879

Query: 942   IPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKP-----------LT 990
              P     E    +  S+   A VTGLS G  Y F+V A +   +S P           LT
Sbjct: 17880 QPKGT--EKWSIVAESKVCNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLT 17937

Query: 991   AQQTTKLDAPT-NLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQP----RQYNVG 1045
              Q + KL   T ++Q   +    + V   P        R  +   + G+P     + NV 
Sbjct: 17938 IQPSLKLPFNTYSIQAGEDLKIEIPVIGRP--------RPNISWVKDGEPLKQTTRVNVE 17989

Query: 1046  PSVSKYPLR----NLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYN-TEVTE 1100
              + +   L     N     +YTV+     G   + +   V    +PG  + P    EV+ 
Sbjct: 17990 ETATSTVLHIKEGNKDDFGKYTVTATNSAGT--ATENLSVIVLEKPGPPVGPVRFDEVSA 18047

Query: 1101  TTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIV----------VSGLTPGVEYV 1150
               +VI+W P    G   G + S      R+ T+ +  +V          ++ L  G EY 
Sbjct: 18048 DFVVISWEPPAYTG---GCQISNYIVEKRDTTTTTWHMVSATVARTTIKITKLKTGTEYQ 18104

Query: 1151  YTIQVLRDGQERDAPIVNKVVTPLSP-----PTNLHLEANPDTGVLTVSWERSTTPD--- 1202
             + I    +   + AP+ +K V    P     P       +     + V W          
Sbjct: 18105 FRI-FAENRYGKSAPLDSKAVIVQYPFKEPGPPGTPFVTSISKDQMLVQWHEPVNDGGTK 18163

Query: 1203  ITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYN--VSVYTVKDDKESVPIS 1260
             I GY +     N      L +    D    T   L  GLEY   VS   +    +   +S
Sbjct: 18164 IIGYHLEQKEKNSILWVKLNKTPIQDTKFKT-TGLDEGLEYEFKVSAENIVGIGKPSKVS 18222

Query: 1261  DTIIPAVP--PPTDLRFTNIGPDTMRVTWAPPP---SIDLTNFLVRYSPVKNEEDVAELS 1315
             +  +   P  PP       I  + + + W  P       +T ++V     K+  D   + 
Sbjct: 18223 ECFVARDPCDPPGRPEAIVITRNNVTLKWKKPAYDGGSKITGYIVEK---KDLPDGRWMK 18279

Query: 1316  ISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFT 1375
              S        TN+L  TE+ VS   V +Q     +  R   G  S        ITA    
Sbjct: 18280 AS-------FTNVLE-TEFTVS-GLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARD-- 18328

Query: 1376  VHWIAPRATITG-YR---IRHHPEHF------SGRPREDRV--------------PHSRN 1411
                 AP A++   Y+   + H  E F       G+P  D V                 ++
Sbjct: 18329 -EIDAPNASLDPKYKDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKS 18387

Query: 1412  SITLTNL-------TPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSL 1464
             +I  T L       T G +Y++ +  + G +  P+ +            L+V   T    
Sbjct: 18388 TIQKTTLVVKDCIRTDGGQYILKLSNVGGTKSIPITVKVLDRPGPPEGPLKVTGVTAEKC 18447

Query: 1465  LISWDAP----AVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYA 1520
              ++W+ P       + +Y I   ET   S  Q  T   + +   ++ L PG +Y   V A
Sbjct: 18448 YLAWNPPLQDGGANISHYIIEKRETSRLSWTQVSTEVQALNYK-VTKLLPGNEYIFRVMA 18506

Query: 1521  VTGRG-DSPASSKPISI-NYRTEIDKPSQMQVTDVQDNSISVKWL----PSSSPVTGYRV 1574
             V   G   P  S P++  N       PS  +V+ +  +S+ V W        + + GY +
Sbjct: 18507 VNKYGIGEPLESGPVTACNPYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYIL 18566

Query: 1575  TTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQT------- 1627
                 K G   TK          + + GL     Y   V A+N +G  +P   +       
Sbjct: 18567 EKRDKEGVRWTKCNKKTLTDLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRACD 18626

Query: 1628  AVTNIDRPKGLAFTDVDVDSIKIAWESP----QGQVSRYRVTYSSPEDGIHELFPAPDGE 1683
             A+     P     TD    S+ +AW  P       V  Y V               P G 
Sbjct: 18627 ALYPPGPPSNPKVTDTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAADEWTTCTPPTGL 18686

Query: 1684  EDTA-ELQGLRPGSEYTVSVVALHDDMESQPL-----IGTQSTAIPAPTDLKFTQVTPTS 1737
             +     +  L+  +EY   + A++ +   +P      +  Q    P   +L         
Sbjct: 18687 QGKQFTVTKLKENTEYNFRICAINSEGVGEPATLPGSVVAQERIEPPEIELDADLRKVVV 18746

Query: 1738  LSAQWTPPNVQLTGYRVRVTPKEKTGPM----KEINLAPDSSSVVVSGLMV------ATK 1787
             L A  T         R+ VT K +  P     K   +  D + + V+           T+
Sbjct: 18747 LRASAT--------LRLFVTIKGRPEPEVKWEKAEGILTDRAQIEVTSSFTMLVIDNVTR 18798

Query: 1788  YEVSVY--ALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKT----ETI 1841
             ++   Y   L++   S+ A   V  L++ S P    + +  + ++T+SW          I
Sbjct: 18799 FDSGRYNLTLENNSGSKTAFVNVRVLDSPSAPVNLTIREVKKDSVTLSWEPPLIDGGAKI 18858

Query: 1842  TGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDAST 1901
             T + V+      +     T      ++ I  LQ G  Y   +   N+     P       
Sbjct: 18859 TNYIVEKRETTRKAYATITNNCTKTTFRIENLQEGCSYYFRVLASNEYGIGLPAETTEPV 18918

Query: 1902  AIDAP----SNLRFLATTPNSLLVSWQPPRA----RITGYIIKYEKPGSPPREVVPRPRP 1953
              +  P      +  +  T N+  + W+ P +    +ITGY+++ +  GS       + + 
Sbjct: 18919 KVSEPPLPPGRVTLVDVTRNTATIKWEKPESDGGSKITGYVVEMQTKGSEKWSTCTQVK- 18977

Query: 1954  GVTEATITGLEPGTEYTIYVIALKNNQKSEP 1984
                EATI+GL  G EY   V A+    +S+P
Sbjct: 18978 -TLEATISGLTAGEEYVFRVAAVNEKGRSDP 19007



 Score =  132 bits (332), Expect = 4e-30
 Identities = 282/1282 (21%), Positives = 484/1282 (37%), Gaps = 198/1282 (15%)

Query: 611   PVEVFITETPSQPNSHPIQWNAP---QPSHISKYILRWRPKNSVGRWKEATIPGHLNSYT 667
             PV V + E     +S  + W  P     S I  Y+++ R       W   T      S+ 
Sbjct: 13418 PVNVTVKEISK--DSAYVTWEPPIIDGGSPIINYVVQKRDAERKS-WSTVTTECSKTSFR 13474

Query: 668   IKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSES 727
             +  L+ G  Y  ++ +  +YG  +               T + V    TP  P+V     
Sbjct: 13475 VANLEEGKSYFFRVFAENEYGIGDPGE------------TRDAVKASQTP-GPVVDLK-- 13519

Query: 728   VTEITASSFVVSWVS----ASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPG 783
             V  ++ SS  + W          + G+ V++ L+EE    + +   S +   +  DL  G
Sbjct: 13520 VRSVSKSSCSIGWKKPHSDGGSRIIGYVVDF-LTEENKWQRVMK--SLSLQYSAKDLTEG 13576

Query: 784   RKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWS---RPQAPITG 840
             ++Y   V   +E+GE +    T         PD  +  + D   + + +   R + PI G
Sbjct: 13577 KEYTFRVSAENENGEGTPSEITVVARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPIKG 13636

Query: 841   YRIVYSPSVE--------GSSTELNLPETANSVTLS--DLQPGV--QYNITIYAVEENQE 888
                  +PSV          + T +++  +A + TL   D Q     +Y IT+  V   +E
Sbjct: 13637 KP---APSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKE 13693

Query: 889   STPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPV 944
              T   I  +  G P   T P    ++F EVT   +T+ W PP+    S +T Y ++    
Sbjct: 13694 GT---ISIKVVGKPGIPTGP----IKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDS 13746

Query: 945   NLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKV-----FAVSHGRESKPLTAQQTTKL-D 998
                        + + TF  VT L  G+ Y F+V     + V  G +S+P+ A+    + D
Sbjct: 13747 VNNKWVTCASAVQKTTF-RVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVPD 13805

Query: 999   APTNLQFVNETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGP-SVSKYPL 1053
             AP     V+    +V + WT P+    + ITGY L          ++ N  P  +  + +
Sbjct: 13806 APPPPNIVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTPIRMRDFKV 13865

Query: 1054  RNLQPASEYTVSLVAIK----GNQESPKATGVFTTLQPGSSIPPYNTEV---TETTIVIT 1106
               L    EY   ++AI     G    P    V   L P    PP   EV   T  ++ + 
Sbjct: 13866 TGLTEGLEYEFRVMAINLAGVGKPSLPSEPVV--ALDPID--PPGKPEVINITRNSVTLI 13921

Query: 1107  WT-PAPRIGFKLGVR-------PSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRD 1158
             WT P    G KL          PS+       V     +  V+ L  G +Y + I+    
Sbjct: 13922 WTEPKYDGGHKLTGYIVEKRDLPSKSWMKANHVNVPECAFTVTDLVEGGKYEFRIRAKNT 13981

Query: 1159  GQERDAPIVN----------KVVTPLSPPT---NLHLEANPDTGVLTV-----------S 1194
                  AP  +          +  T +  PT    L ++A  DT VL             S
Sbjct: 13982 AGAISAPSESTETIICKDEYEAPTIVLDPTIKDGLTIKAG-DTIVLNAISILGKPLPKSS 14040

Query: 1195  WERS----TTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTV 1250
             W ++       DIT  +IT+TPT+     +++     D    T    +P   +   V  V
Sbjct: 14041 WSKAGKDIRPSDIT--QITSTPTSSML--TIKYATRKDAGEYTITATNP---FGTKVEHV 14093

Query: 1251  KDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEED 1310
             K          T++    PP  +  +N+  +   +TW PP   D  + +  Y   K E  
Sbjct: 14094 KV---------TVLDVPGPPGPVEISNVSAEKATLTWTPPLE-DGGSPIKSYILEKRETS 14143

Query: 1311  VAELSISPSDNAV---VLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLD------SP 1361
                 ++   D      V T L+ G EY+  VS+V    +  P++      +D       P
Sbjct: 14144 RLLWTVVSEDIQSCRHVATKLIQGNEYIFRVSAVNHYGKGEPVQSEPVKMVDRFGPPGPP 14203

Query: 1362  TGIDFSDITANSFTVHWIAP----RATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTN 1417
                + S++T N+ TV W  P     + ITGY +    +      R  + P S     +T 
Sbjct: 14204 EKPEVSNVTKNTATVSWKRPVDDGGSEITGYHVERREKKSLRWVRAIKTPVSDLRCKVTG 14263

Query: 1418  LTPGTEYVVSIVALNGREESP-------LLIGQQSTVSDVPRDLEVVAATPTSLLISWDA 1470
             L  G+ Y   + A N     P       +L+   +     P +  V   T  S  ++W  
Sbjct: 14264 LQEGSTYEFRVSAENRAGIGPPSEASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLAWGK 14323

Query: 1471  P----AVTVRYYRITYGETGGNSPVQEFTVPGSKSTA-TISGLKPGVDYTITVYAVTGRG 1525
             P     + +  Y + + + G  + +++ T    + T   +  L+    Y   + A+   G
Sbjct: 14324 PHYDGGLEITGYVVEHQKVGDEAWIKDTTGTALRITQFVVPDLQTKEKYNFRISAINDAG 14383

Query: 1526  -DSPASSKPISINYR---TEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNG 1581
                PA    + I  R    + +  ++++ T V    +S++            VT T  N 
Sbjct: 14384 VGEPAVIPDVEIVEREMAPDFELDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNI 14443

Query: 1582  PGPTKTKTAGPDQTEMTIE---GLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRP-KG 1637
                 +      +   + I        T ++V+++  +NP+G+    V   V +   P   
Sbjct: 14444 NLKNRANIENTESFTLLIIPECNRYDTGKFVMTI--ENPAGKKSGFVNVRVLDTPGPVLN 14501

Query: 1638  LAFTDVDVDSIKIAWESP----QGQVSRY--------RVTYSSPEDGIHELFPAPDGEED 1685
             L  TD+  DS+ + W+ P      +++ Y        R +YS+     H+          
Sbjct: 14502 LRPTDITKDSVTLHWDLPLIDGGSRITNYIVEKREATRKSYSTATTKCHKC--------- 14552

Query: 1686  TAELQGLRPGSEYTVSVVALHDDMESQPLIGTQ---STAIPAPTD-LKFTQVTPTSLSAQ 1741
             T ++ GL  G EY   V+A ++    +P   T+   ++  P+P D L    +T +++S  
Sbjct: 14553 TYKVTGLSEGCEYFFRVMAENEYGIGEPTETTEPVKASEAPSPPDSLNIMDITKSTVSLA 14612

Query: 1742  WTPP----NVQLTGYRVRVTPK 1759
             W  P      ++TGY +    K
Sbjct: 14613 WPKPKHDGGSKITGYVIEAQRK 14634



 Score =  129 bits (324), Expect = 3e-29
 Identities = 296/1415 (20%), Positives = 523/1415 (36%), Gaps = 202/1415 (14%)

Query: 728   VTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTAT----SVNIPDLLPG 783
             + ++++    V W    D   G  ++  + E+ +  + +    +AT       +  L+ G
Sbjct: 11933 IVDVSSDRCTVCWDPPEDD-GGCEIQNYILEKCETKRMVWSTYSATVLTPGTTVTRLIEG 11991

Query: 784   RKYIVNVYQISEDG-----EQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ--- 835
              +YI  V   ++ G     E   +++ ++   P  P  P V +V    + V W+ P+   
Sbjct: 11992 NEYIFRVRAENKIGTGPPTESKPVIAKTKYDKPGRPDPPEVTKVSKEEMTVVWNPPEYDG 12051

Query: 836   -APITGYRIVYSPSVEGSSTELN---LPETANSVTLSDLQPGVQYNITIYAVEENQESTP 891
                ITGY +            +N   +PE    V   +L P  +Y   + A  E     P
Sbjct: 12052 GKSITGYFLEKKEKHSTRWVPVNKSAIPERRMKV--QNLLPDHEYQFRVKAENEIGIGEP 12109

Query: 892   VVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPVNL- 946
              +  +        +    P + + V+ T   +T+ W  P     + + GY V++ P    
Sbjct: 12110 SLPSRPVVAKDPIEPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAPIIGYVVEMRPKIAD 12169

Query: 947   --PGEHGQRL----PISRNTFAEVTGLSPGVTYYFKVFA---VSHGRESKPLTAQQTTKL 997
               P E  +R      + R  F  VT L     Y F+V A   V  GR ++   A +  ++
Sbjct: 12170 ASPDEGWKRCNAAAQLVRKEFT-VTSLDENQEYEFRVCAQNQVGIGRPAELKEAIKPKEI 12228

Query: 998   DAPTNLQFVNETDSTVLVRWT-----------PPRAQITGYRLTV-GLTRRGQPRQYNVG 1045
               P  +         V+VR              P  ++T  ++ +  + R+GQ    +  
Sbjct: 12229 LEPPEIDLDASMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVVRKGQVDLVDT- 12287

Query: 1046  PSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVI 1105
              +    P      + +Y+++LV   G +       V  T  P S +    ++VT+T+  +
Sbjct: 12288 MAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFVNVRVLDTPGPVSDLKV--SDVTKTSCHV 12345

Query: 1106  TWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIV----------VSGLTPGVEYVYTIQV 1155
             +W P    G   G + +      RE    + S V          V+ L PG EY + +  
Sbjct: 12346 SWAPPENDG---GSQVTHYIVEKREADRKTWSTVTPEVKKTSFHVTNLVPGNEYYFRVTA 12402

Query: 1156  LRD---GQERDAPIVNKVVTPLS---PPTNLHLEANPDTGVLTVSWE---RSTTPDITGY 1206
             + +   G   D P       PLS   PP  L +         T++W    R     I GY
Sbjct: 12403 VNEYGPGVPTDVPKPVLASDPLSEPDPPRKLEVTEMTKNSA-TLAWLPPLRDGGAKIDGY 12461

Query: 1207  RITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYT-----VKDDKESVPISD 1261
              IT+     Q  +   E       S     L  G +Y   V       V   +E+  + +
Sbjct: 12462 -ITSYREEEQPADRWTEYSVVKDLSLVVTGLKEGKKYKFRVAARNAVGVSLPREAEGVYE 12520

Query: 1262  TIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVK---NEEDV---AELS 1315
                  +PP        + P+ + +       I+   +   +   K    E++V   + L+
Sbjct: 12521 AKEQLLPPKI------LMPEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLA 12574

Query: 1316  ISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSP----TGIDFSDITA 1371
             +  +D++ +L       +     S   E    T  +  +   +D+P       D SDI A
Sbjct: 12575 VHKADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPGPPQPPFDISDIDA 12634

Query: 1372  NSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPH----SRNSITLTNLTPGTEYVVS 1427
             ++ ++ W  P     G  I ++        R D V      ++ S  +  L PG EY+  
Sbjct: 12635 DACSLSWHIPLED-GGSNITNYIVEKCDVSRGDWVTALASVTKTSCRVGKLIPGQEYIFR 12693

Query: 1428  IVALN--GREE---SPLLIGQ-QSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRIT 1481
             + A N  G  E   SP ++ Q    V   P++  V       + ++WD P          
Sbjct: 12694 VRAENRFGISEPLTSPKMVAQFPFGVPSEPKNARVTKVNKDCIFVAWDRP---------- 12743

Query: 1482  YGETGGNSPVQEFTVPGSKSTATI----------------SGLKPGVDYTITVYAVTGRG 1525
               ++ G SP+  + +   +  + +                +GL  G++Y+  +YA+   G
Sbjct: 12744 --DSDGGSPIIGYLIERKERNSLLWVKANDTLVRSTEYPCAGLVEGLEYSFRIYALNKAG 12801

Query: 1526  DSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWL----PSSSPVTGYRVTTTPKNG 1581
              SP S     +  R  +D P + +V DV  +++S+ W        S + GY V      G
Sbjct: 12802 SSPPSKPTEYVTARMPVDPPGKPEVIDVTKSTVSLIWARPKHDGGSKIIGYFVEACKLPG 12861

Query: 1582  PGPTKTKTAGPD--QTEMTIEGLQPTVEYVVSVYAQN------PSGESQP---LVQTAVT 1630
                 +  TA     Q E T  GL+   +Y     A+       PS  S P   L +    
Sbjct: 12862 DKWVRCNTAPHQIPQEEYTATGLEEKAQYQFRAIARTAVNISPPSEPSDPVTILAENVPP 12921

Query: 1631  NIDRPKGL-------AFTDVDVDSIKIAWESPQGQVS-RYRVTYSSPEDGIHELFPAPDG 1682
              ID    +       A T+V +D+    +  P   VS +   T   P +GI     A   
Sbjct: 12922 RIDLSVAMKSLLTVKAGTNVCLDA--TVFGKPMPTVSWKKDGTLLKPAEGIK---MAMQR 12976

Query: 1683  EEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPA-PTDLKFTQVTPTSLSAQ 1741
                T EL  +        ++ A +        I  +    P  P  +K  ++        
Sbjct: 12977 NLCTLELFSVNRKDSGDYTITAENSSGSKSATIKLKVLDKPGPPASVKINKMYSDRAMLS 13036

Query: 1742  WTPP----NVQLTGYRVRVTPKEKTGP-MKEINLAPDSSSVVVSGLMVATKYEVSV---- 1792
             W PP      ++T Y   V  +E + P   +++     +S  V  L+   +Y+  +    
Sbjct: 13037 WEPPLEDGGSEITNY--IVDKRETSRPNWAQVSATVPITSCSVEKLIEGHEYQFRICAEN 13094

Query: 1793  -YALKDTLTSRPAQGVVTTLENVSPPRRAR---VTDATETTITISWRTKTE----TITGF 1844
              Y + D + + PA           PP R     +++ T+  +T+SW+   +     ITG+
Sbjct: 13095 KYGVGDPVFTEPA----IAKNPYDPPGRCDPPVISNITKDHMTVSWKPPADDGGSPITGY 13150

Query: 1845  QVDAVPANGQTPIQRTIKPDV-RSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAI 1903
              ++          +   KP + R+   TGLQ GT+Y+  +  +N      P   DAS A 
Sbjct: 13151 LLEKRETQAVNWTKVNRKPIIERTLKATGLQEGTEYEFRVTAINKAGPGKP--SDASKAA 13208

Query: 1904  DA---------PSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREVVPR 1950
              A         P+  +   TT +S+ +SW  P     + I GY+++ ++  S        
Sbjct: 13209 YARDPQYPPGPPAFPKVYDTTRSSVSLSWGKPAYDGGSPIIGYLVEVKRADSDNWVRCNL 13268

Query: 1951  PRP-GVTEATITGLEPGTEYTIYVIALKNNQKSEP 1984
             P+    T   +TGL   T+Y   V A+     S+P
Sbjct: 13269 PQNLQKTRFEVTGLMEDTQYQFRVYAVNKIGYSDP 13303



 Score =  123 bits (309), Expect = 2e-27
 Identities = 282/1358 (20%), Positives = 482/1358 (35%), Gaps = 200/1358 (14%)

Query: 780   LLPGRKYIVNVYQISEDGE----QSLILSTSQTTAPDAPPD-PTVDQVDDTSIVVRWSRP 834
             L+ G +YI  V  ++  G+    QS  +       P  PP+ P V  V   +  V W RP
Sbjct: 14164 LIQGNEYIFRVSAVNHYGKGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSWKRP 14223

Query: 835   Q----APITGYRIVYSPSVEGSSTE-LNLPETANSVTLSDLQPGVQYNITIYA-----VE 884
                  + ITGY +             +  P +     ++ LQ G  Y   + A     + 
Sbjct: 14224 VDDGGSEITGYHVERREKKSLRWVRAIKTPVSDLRCKVTGLQEGSTYEFRVSAENRAGIG 14283

Query: 885   ENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPES----AVTGYRVD 940
                E++  V+ ++    P   + P   D      T    ++ W  P       +TGY V+
Sbjct: 14284 PPSEASDSVLMKDAAYPPGPPSNPHVTD-----TTKKSASLAWGKPHYDGGLEITGYVVE 14338

Query: 941   VIPVN----LPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQ--QT 994
                V     +    G  L I++     V  L     Y F++ A++     +P      + 
Sbjct: 14339 HQKVGDEAWIKDTTGTALRITQFV---VPDLQTKEKYNFRISAINDAGVGEPAVIPDVEI 14395

Query: 995   TKLDAPTNLQFVNETDSTVLVR-------WTP----PRAQITGYRLTVGLTRRGQPRQYN 1043
              + +   + +   E   T++VR       + P    P  ++T  +  + L  R       
Sbjct: 14396 VEREMAPDFELDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKNRANIENTE 14455

Query: 1044  VGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTI 1103
                ++   P  N     ++ +++    G +       V  T  P  ++ P  T++T+ ++
Sbjct: 14456 -SFTLLIIPECNRYDTGKFVMTIENPAGKKSGFVNVRVLDTPGPVLNLRP--TDITKDSV 14512

Query: 1104  VITWT-PAPRIGFKLGVRPSQGGEAPREVTSDSGS------IVVSGLTPGVEYVYTIQVL 1156
              + W  P    G ++     +  EA R+  S + +        V+GL+ G EY + +   
Sbjct: 14513 TLHWDLPLIDGGSRITNYIVEKREATRKSYSTATTKCHKCTYKVTGLSEGCEYFFRVMAE 14572

Query: 1157  RD---GQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPD---ITGYRITT 1210
              +   G+  +     K     SPP +L++  +     ++++W +        ITGY I  
Sbjct: 14573 NEYGIGEPTETTEPVKASEAPSPPDSLNI-MDITKSTVSLAWPKPKHDGGSKITGYVIEA 14631

Query: 1211  TPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTII----PA 1266
                   Q   +  V   +   C   NL+ G EY   V  V     S P     +      
Sbjct: 14632 QRKGSDQWTHITTVKGLE---CVVRNLTEGEEYTFQVMAVNSAGRSAPRESRPVIVKEQT 14688

Query: 1267  VPPPTDLR-------FTNIGPDT---MRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSI 1316
             + P  DLR           G +    + V   P P++            K  + + + + 
Sbjct: 14689 MLPELDLRGIYQKLVIAKAGDNIKVEIPVLGRPKPTVTW----------KKGDQILKQTQ 14738

Query: 1317  SPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGL-------------DSPTG 1363
               +      + +L   E V S S  Y      PL  R   G                PTG
Sbjct: 14739 RVNFETTATSTILNINECVRSDSGPY------PLTARNIVGEVGDVITIQVHDIPGPPTG 14792

Query: 1364  -IDFSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNL 1418
              I F +++++  T  W  P       I+ Y +       S    E      R +   T L
Sbjct: 14793 PIKFDEVSSDFVTFSWDPPENDGGVPISNYVVEMRQTD-STTWVELATTVIRTTYKATRL 14851

Query: 1419  TPGTEYVVSIVALN------GREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAP- 1471
             T G EY   + A N      G   + ++      V   P   +V A T  S+ ISW  P 
Sbjct: 14852 TTGLEYQFRVKAQNRYGVGPGITSACIVANYPFKVPGPPGTPQVTAVTKDSMTISWHEPL 14911

Query: 1472  ---AVTVRYYRITYGETGGN--SPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGD 1526
                   +  Y +   E  G     V +  VPG+   +  SGL  G+ Y   V A    G 
Sbjct: 14912 SDGGSPILGYHVERKERNGILWQTVSKALVPGNIFKS--SGLTDGIAYEFRVIAENMAGK 14969

Query: 1527  SPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKW----LPSSSPVTGYRVTTTPKNGP 1582
             S  S     +     ID P +    ++  +++++KW          +T Y V        
Sbjct: 14970 SKPSKPSEPMLALDPIDPPGKPVPLNITRHTVTLKWAKPEYTGGFKITSYIVEKRDLPNG 15029

Query: 1583  GPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQ--TAVTNIDRPKGLAF 1640
                K   +   + E T+ GL     Y   V A+N +G   P  +   A+T  D       
Sbjct: 15030 RWLKANFSNILENEFTVSGLTEDAAYEFRVIAKNAAGAISPPSEPSDAITCRD------- 15082

Query: 1641  TDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGL-------- 1692
              DV+   IK+  +     + +    +    D      P  +  +D  EL+G         
Sbjct: 15083 -DVEAPKIKVDVKFKDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIA 15141

Query: 1693  -------------RPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTD--LKFTQVTPTS 1737
                          R    YT++  A +    ++ +   +    P P +  L  T+VT   
Sbjct: 15142 DFSTNLVNKDSTRRDSGAYTLT--ATNPGGFAKHIFNVKVLDRPGPPEGPLAVTEVTSEK 15199

Query: 1738  LSAQWTPP----NVQLTGYRVRVTPKEKTGPMKEINLAPD--SSSVVVSGLMVATKY--- 1788
                 W PP      ++  Y   +  K +T  +   N+A +   + + V+ L+   +Y   
Sbjct: 15200 CVLSWFPPLDDGGAKIDHY---IVQKRETSRLAWTNVASEVQVTKLKVTKLLKGNEYIFR 15256

Query: 1789  --EVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISW----RTKTETIT 1842
                V+ Y + + L S P    V       PP+   VT  T+ ++ + W          I 
Sbjct: 15257 VMAVNKYGVGEPLESEPVL-AVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEII 15315

Query: 1843  GFQVDAVPANGQTPIQRTIK--PDVRSYTITGLQPGTDYKIYLYTLNDNARSSP------ 1894
              + V+     GQ  I+   K   D+R Y ++GL  G +Y+  +   N    S+P      
Sbjct: 15316 NYIVERRDKAGQRWIKCNKKTLTDLR-YKVSGLTEGHEYEFRIMAENAAGISAPSPTSPF 15374

Query: 1895  -VVIDASTAIDAPSNLRFLATTPNSLLVSWQPP----RARITGYIIKYEKPGSPPREVVP 1949
                 D       P N R L T+ +S+ ++W  P     + ITGY+++   P     ++V 
Sbjct: 15375 YKACDTVFKPGPPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQIVT 15434

Query: 1950  RPRP-GVTEATITGLEPGTEYTIYVIALKNNQKSEPLI 1986
              P     T  TITGL    EY I + A+ +    EP +
Sbjct: 15435 PPAGLKATSYTITGLTENQEYKIRIYAMNSEGLGEPAL 15472



 Score =  121 bits (303), Expect = 9e-27
 Identities = 287/1414 (20%), Positives = 508/1414 (35%), Gaps = 177/1414 (12%)

Query: 610   GPVEVFITETPSQPNSHPIQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSY 666
             GP E  +  T        + WN P     ++IS YI+  R  + +  W + +      +Y
Sbjct: 18431 GPPEGPLKVTGVTAEKCYLAWNPPLQDGGANISHYIIEKRETSRLS-WTQVSTEVQALNY 18489

Query: 667   TIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSE 726
              +  L PG  Y  +++++ +YG  E             P+ S  VT       P   ++ 
Sbjct: 18490 KVTKLLPGNEYIFRVMAVNKYGIGE-------------PLESGPVTACNPYKPPGPPSTP 18536

Query: 727   SVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEP-----QYLDLPSTATSVNIPDLL 781
              V+ IT  S VV+W    D   G  +E  + E+ D+      +      T   + +  L 
Sbjct: 18537 EVSAITKDSMVVTWARPVDD-GGTEIEGYILEKRDKEGVRWTKCNKKTLTDLRLRVTGLT 18595

Query: 782   PGRKY-----IVNVYQISEDGEQSLILSTSQTTAPDAPP-DPTVDQVDDTSIVVRWSRP- 834
              G  Y       N   + E  E S+         P  PP +P V     +S+ + WS+P 
Sbjct: 18596 EGHSYEFRVAAENAAGVGEPSEPSVFYRACDALYPPGPPSNPKVTDTSRSSVSLAWSKPI 18655

Query: 835   ---QAPITGYRIVYSPSVEGSSTELNLPE--TANSVTLSDLQPGVQYNITIYAVEENQES 889
                 AP+ GY +    +     T    P        T++ L+   +YN  I A+      
Sbjct: 18656 YDGGAPVKGYVVEVKEAAADEWTTCTPPTGLQGKQFTVTKLKENTEYNFRICAINSEGVG 18715

Query: 890   TPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVK--------VTIMWTP-PE---SAVTGY 937
              P  +        R +      D    +V  ++        VTI   P PE       G 
Sbjct: 18716 EPATLPGSVVAQERIEPPEIELDADLRKVVVLRASATLRLFVTIKGRPEPEVKWEKAEGI 18775

Query: 938   RVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKL 997
               D   + +          +      VT    G   Y      + G ++  +  +     
Sbjct: 18776 LTDRAQIEVTSS------FTMLVIDNVTRFDSG--RYNLTLENNSGSKTAFVNVRVLDSP 18827

Query: 998   DAPTNLQFVNETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSVSKYPL 1053
              AP NL        +V + W PP     A+IT Y +    T R          + + + +
Sbjct: 18828 SAPVNLTIREVKKDSVTLSWEPPLIDGGAKITNYIVEKRETTRKAYATITNNCTKTTFRI 18887

Query: 1054  RNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYN------TEVTETTIVITW 1107
              NLQ    Y   ++A   + E        TT     S PP         +VT  T  I W
Sbjct: 18888 ENLQEGCSYYFRVLA---SNEYGIGLPAETTEPVKVSEPPLPPGRVTLVDVTRNTATIKW 18944

Query: 1108  T-PAPRIGFKLG----VRPSQGGEAPREVTS-DSGSIVVSGLTPGVEYVYTIQVLR---- 1157
               P    G K+        ++G E     T   +    +SGLT G EYV+ +  +     
Sbjct: 18945 EKPESDGGSKITGYVVEMQTKGSEKWSTCTQVKTLEATISGLTAGEEYVFRVAAVNEKGR 19004

Query: 1158  -DGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGY-RITTTPTNG 1215
              D ++   P++ + +  + P   L            V        D+    R   T    
Sbjct: 19005 SDPRQLGVPVIARDIE-IKPSVELPFHT------FNVKAREQLKIDVPFKGRPQATVNWR 19057

Query: 1216  QQGNSLEEVVHADQSSC---TFDNLSPGLEYNVSVYTVKDDKES----VPISDTIIPAVP 1268
             + G +L+E    + SS    T  ++    + +V  Y +     +    VPI+  ++    
Sbjct: 19058 KDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSNSAGSITVPITIIVLDRPG 19117

Query: 1269  PPTDLRFTNIGPDTMRVTWAPPP---SIDLTNFLVRYSPVKNEEDVAE---LSISPSDNA 1322
             PP  +R   +  D++ ++W PP       ++N++V     K E        +S + +  +
Sbjct: 19118 PPGPIRIDEVSCDSITISWNPPEYDGGCQISNYIVE----KKETTSTTWHIVSQAVARTS 19173

Query: 1323  VVLTNLLPGTEYVVSVSS-----VYEQHESTPLRGRQKTGLDSPTGI-DFSDITANSFTV 1376
             + +  L  G+EY   V +          ES+ +          P G       T ++  V
Sbjct: 19174 IKIVRLTTGSEYQFRVCAENRYGKSSYSESSAVVAEYPFSPPGPPGTPKVVHATKSTMLV 19233

Query: 1377  HWIAP----RATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN 1432
              W  P     + + GY + +         + +++  +   + ++ L  G  Y   + A N
Sbjct: 19234 TWQVPVNDGGSRVIGYHLEYKERSSILWSKANKILIADTQMKVSGLDEGLMYEYRVYAEN 19293

Query: 1433  ----GREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAP----AVTVRYYRITYGE 1484
                 G+              D P   EV   T  S+ + W  P       +  Y +   E
Sbjct: 19294 IAGIGKCSKSCEPVPARDPCDPPGQPEVTNITRKSVSLKWSKPHYDGGAKITGYIVERRE 19353

Query: 1485  TGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGD-SPASSKPISINYRTEID 1543
                   ++       ++   ++ L     Y   V+A       S  S     I  + +++
Sbjct: 19354 LPDGRWLKCNYTNIQETYFEVTELTEDQRYEFRVFARNAADSVSEPSESTGPIIVKDDVE 19413

Query: 1544  KPSQMQVTDVQDNSI--SVKWLPSSSPVTG--YRVTTTPKNG---PGPTKTKTAGPD-QT 1595
              P  M     +D  +  + + L  ++ + G    V +  K+G       +T+    D  T
Sbjct: 19414 PPRVMMDVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTDNHT 19473

Query: 1596  EMTIEGL--QPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKG--LAFTDVDVDSIKIA 1651
              +T++    + T +YV+++  +N +G     V   V +   P    L    +  +   ++
Sbjct: 19474 LLTVKDCIRRDTGQYVLTL--KNVAGTRSVAVNCKVLDKPGPPAGPLEINGLTAEKCSLS 19531

Query: 1652  WESPQ----GQVSRYRVTYSSPEDGIHELFPAPDGE--EDTAELQGLRPGSEYTVSVVAL 1705
             W  PQ      +  Y V      +  H  +   +GE    + ++  L  G+EY   V  +
Sbjct: 19532 WGRPQEDGGADIDYYIV---EKRETSHLAWTICEGELQMTSCKVTKLLKGNEYIFRVTGV 19588

Query: 1706  HDDMESQPLIGTQSTAIPA---------PTDLKFTQVTPTSLSAQWTPP----NVQLTGY 1752
             +     +PL   +S AI A         PT L+ T VT  S++  W+ P      +++GY
Sbjct: 19589 NKYGVGEPL---ESVAIKALDPFTVPSPPTSLEITSVTKESMTLCWSRPESDGGSEISGY 19645

Query: 1753  RVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQ--GVVTT 1810
              +    K     ++          V  +GL    +YE  VYA      S P++   ++  
Sbjct: 19646 IIERREKNSLRWVRVNKKPVYDLRVKSTGLREGCEYEYRVYAENAAGLSLPSETSPLIRA 19705

Query: 1811  LENV---SPPRRARVTDATETTITISWRTKT----ETITGFQVD---AVPANGQTPIQRT 1860
              + V   SPP + ++ D+ +TTITI+W          ITG+ V+   +   + +T IQ  
Sbjct: 19706 EDPVFLPSPPSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEYKKSDDTDWKTSIQSL 19765

Query: 1861  IKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSP 1894
                +   YTI+GL  G +Y   + ++N    S P
Sbjct: 19766 RGTE---YTISGLTTGAEYVFRVKSVNKVGASDP 19796



 Score =  120 bits (302), Expect = 1e-26
 Identities = 326/1553 (20%), Positives = 547/1553 (35%), Gaps = 248/1553 (15%)

Query: 605  YPSSSGPVEVFITETPSQPNSHPIQWNAPQ---PSHISKYILRWRPKNSVGRWKEA-TIP 660
            Y     P+ V IT+      S  + W  P+    + I+ Y++  R K S+ RW  A T+ 
Sbjct: 6816 YDVPGPPLNVTITDVNRFGVS--LTWEPPEYDGGAEITNYVIELRDKTSI-RWDTAMTVR 6872

Query: 661  GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP 720
                S T+       V EGQ  S +        R      S +TP        E  P  P
Sbjct: 6873 AEDLSATVTD-----VVEGQEYSFRVRAQN---RIGVGKPSAATPFVKVADPIER-PSPP 6923

Query: 721  LVATSESVTEITASSFVVSWV----SASDTVSGFRVEYELSEEGDEPQY---LDLPSTAT 773
            +  TS   T+   SS  + W          + G+ +E    EEG +      + L    T
Sbjct: 6924 VNLTSSDQTQ---SSVQLKWEPPLKDGGSPILGYIIER--CEEGKDNWIRCNMKLVPELT 6978

Query: 774  SVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQV---DDTSIVVR 830
               +  L  G KY+  V   ++ G           TA DA  +PT+D     D   ++V 
Sbjct: 6979 -YKVTGLEKGNKYLYRVSAENKAGVSDPSEILGPLTADDAFVEPTMDLSAFKDGLEVIV- 7036

Query: 831  WSRP---QAPITGYRIVYSPSVEGSSTELNLPETANSVTLSD-----LQPGVQYNITIYA 882
               P     P TGY    +    G    L   +     TLS      + P  + +  IY 
Sbjct: 7037 -PNPITILVPSTGYPRPTATWCFGDKV-LETGDRVKMKTLSAYAELVISPSERSDKGIYT 7094

Query: 883  VEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYR 938
            ++       +  + +     R     +P++L+F ++T   V + W PP+    S +TGY 
Sbjct: 7095 LKLENRVKTISGEIDVNVIARPS---APKELKFGDITKDSVHLTWEPPDDDGGSPLTGYV 7151

Query: 939  VDVIPVNLPGEHGQRLPISRNTFAE-----------VTGLSPGVTYYFKVFAVSHGRESK 987
            V            ++  +SR T+ +           V  L  G  Y FKV A +     +
Sbjct: 7152 V------------EKREVSRKTWTKVMDFVTDLEFTVPDLVQGKEYLFKVCARNKCGPGE 7199

Query: 988  PLTAQQTTKL-------DAPTNLQFVNETDSTVLVRWTPPR----AQITGYRLTVGLTRR 1036
            P    +   +       D P N+++ + T +++ + W PP+    ++I GY   V    R
Sbjct: 7200 PAYVDEPVNMSTPATVPDPPENVKWRDRTANSIFLTWDPPKNDGGSRIKGY--IVERCPR 7257

Query: 1037 GQPRQYNVGPSV--SKYPLRNLQPASEYTVSLVAIK-----------------GNQESPK 1077
            G  +    G  V  +K  +  L+    Y   + A+                    QE+P+
Sbjct: 7258 GSDKWVACGEPVAETKMEVTGLEEGKWYAYRVKALNRQGASKPSRPTEEIQAVDTQEAPE 7317

Query: 1078 ATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGF-KLGVRPSQGGEAPREVTSDSG 1136
               +F  ++  + +        E    +T  P P+I + K  +   Q      E      
Sbjct: 7318 ---IFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPKKS 7374

Query: 1137 SIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHL-EANPDTGVLTVSW 1195
            ++ +          Y I+ +       A +   V+    PP    + +   ++ +LT + 
Sbjct: 7375 TVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNVLDKPGPPAAFDITDVTNESCLLTWNP 7434

Query: 1196 ERST-TPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSV-----YT 1249
             R      IT Y +    T+ +  + L   V       T   L P  EY   V     Y 
Sbjct: 7435 PRDDGGSKITNYVVERRATDSEVWHKLSSTVKDTNFKAT--KLIPNKEYIFRVAAENMYG 7492

Query: 1250 VKDDKESVPISDTIIPAVP-PPTDLRFTNIGPDTMRVTWAPPP---SIDLTNFLVRYSPV 1305
            V +  ++ PI+       P PPT L  ++I  D + +TW  P       +T + V     
Sbjct: 7493 VGEPVQASPITAKYQFDPPGPPTRLEPSDITKDAVTLTWCEPDDDGGSPITGYWVERLDP 7552

Query: 1306 KNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGID 1365
              ++ V    +   D    +  L    +Y   V +        P +  +   +  P    
Sbjct: 7553 DTDKWVRCNKMPVKDTTYRVKGLTNKKKYRFRVLAENLAGPGKPSKSTEPILIKDPIDPP 7612

Query: 1366 F-------SDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPR-EDRVPHSRNSI 1413
            +        D+   S  ++W  P     A I  Y I           R  + VP +++  
Sbjct: 7613 WPPGKPTVKDVGKTSVRLNWTKPEHDGGAKIESYVIEMLKTGTDEWVRVAEGVPTTQH-- 7670

Query: 1414 TLTNLTPGTEYVVSIVALNGREES-------PLLIGQQSTVSDVPRDLEVVAATPTSLLI 1466
             L  L  G EY   + A+N   ES       P+L  ++      PR LEV+  T  +  +
Sbjct: 7671 LLPGLMEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLEVINITKNTADL 7730

Query: 1467 SWDAPAVTVRYYRITYGETGGNSPVQEFTVPG---------------SKSTATISGLKPG 1511
             W  P            E  G SP+  + V                   +  T++ L  G
Sbjct: 7731 KWTVP------------EKDGGSPITNYIVEKRDVRRKGWQTVDTTVKDTKCTVTPLTEG 7778

Query: 1512 VDYTITVYAVTGRGDSPASSKPISINYR---TEIDKPSQMQVTDVQDNSISVKWLPSSS- 1567
              Y   V A    G S  +    S+  +   T    P  + V DV    + +KW P  + 
Sbjct: 7779 SLYVFRVAAENAIGQSDYTEIEDSVLAKDTFTTPGPPYALAVVDVTKRHVDLKWEPPKND 7838

Query: 1568 ---PVTGYRVTTTPKNGPGPTKT-KTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQP 1623
               P+  Y +    + G    K  KTAGPD      + ++ T E    V A+N +G   P
Sbjct: 7839 GGRPIQRYVIEKKERLGTRWVKAGKTAGPDCNFRVTDVIEGT-EVQFQVRAENEAGVGHP 7897

Query: 1624 LVQTAVTNIDRPKG-------LAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHEL 1676
               T + +I+ P         L  TD     I IAW+ P+           SP  G H +
Sbjct: 7898 SEPTEILSIEDPTSPPSPPLDLHVTDAGRKHIAIAWKPPE-------KNGGSPIIGYH-V 7949

Query: 1677 FPAPDGEEDTAEL-------------QGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIP 1723
               P G E    +             +G+ P  EY + V A++    S+P   +++    
Sbjct: 7950 EMCPVGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAIGVSEPSEISENVVAK 8009

Query: 1724 APTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLM 1783
             P D K T    T          + + G ++ +    +  P+  ++   D   V  S  +
Sbjct: 8010 DP-DCKPTIDLETH-------DIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRL 8061

Query: 1784 VATKYEVSVYALKDTLTSRPAQGVVT-TLEN----------------VSPPRRARVTDAT 1826
                  +S + L+   + R   G+ T TLEN                  P +  + +D T
Sbjct: 8062 TMKNDHISAH-LEVPKSVRADAGIYTITLENKLGSATASINVKVIGLPGPCKDIKASDIT 8120

Query: 1827 ETTITISWRTKT----ETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIY 1882
            +++  ++W          I  + ++   A  +T I      +  S+T+  L P  +Y   
Sbjct: 8121 KSSCKLTWEPPEFDGGTPILHYVLERREAGRRTYIPVMSGENKLSWTVKDLIPNGEYFFR 8180

Query: 1883 LYTLND-------NARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPP----RARIT 1931
            +  +N          ++  +  D     D P ++     T  ++ ++W+PP     ++I 
Sbjct: 8181 VKAVNKVGGGEYIELKNPVIAQDPKQPPDPPVDVEVHNPTAEAMTITWKPPLYDGGSKIM 8240

Query: 1932 GYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEP 1984
            GYII+    G    +        +   T  GLE G EY   V A      SEP
Sbjct: 8241 GYIIEKIAKGEERWKRCNEHLVPILTYTAKGLEEGKEYQFRVRAENAAGISEP 8293



 Score =  118 bits (296), Expect = 6e-26
 Identities = 316/1543 (20%), Positives = 554/1543 (35%), Gaps = 238/1543 (15%)

Query: 607   SSSGPVEVFIT----ETPSQPNSHPIQWNAPQPSHISKYILRWRP---------KNSVGR 653
             +SSG    F+T    +TP  P +  ++      +      L W P         KN V  
Sbjct: 17727 NSSGSKSAFVTVKVLDTPGPPQNLAVKEVRKDSA-----FLVWEPPIIDGGAKVKNYVID 17781

Query: 654   WKEATIPGHLN--------SYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTP 705
              +E+T   + N        S+ ++ L  G +Y  ++++  ++G                P
Sbjct: 17782 KRESTRKAYANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFG-------------VGVP 17828

Query: 706   VTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVS----ASDTVSGFRVEYELSEEGD 761
             V +        P SP      ++T+++ +S  + W          V G+ VE  +  +G 
Sbjct: 17829 VETVDAVKAAEPPSP--PGKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVE--MQPKGT 17884

Query: 762   EPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQ 821
             E   +   S   +  +  L  G++Y   V   +E G+    +      A D    P++  
Sbjct: 17885 EKWSIVAESKVCNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKL 17944

Query: 822   VDDTSIVVRWS--RPQAPITGY-RIVYSPSVEGS----STELNLPETANSVTLSDLQPGV 874
               +T  +      + + P+ G  R   S   +G     +T +N+ ETA S  L  ++ G 
Sbjct: 17945 PFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLH-IKEGN 18003

Query: 875   QYNITIYAVEENQESTPV-----VIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTP 929
             + +   Y V     +        VI  E  G P          ++F EV+   V I W P
Sbjct: 18004 KDDFGKYTVTATNSAGTATENLSVIVLEKPGPPVGP-------VRFDEVSADFVVISWEP 18056

Query: 930   PESA----VTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRE 985
             P       ++ Y V+         H     ++R T  ++T L  G  Y F++FA +   +
Sbjct: 18057 PAYTGGCQISNYIVEKRDTTTTTWHMVSATVARTTI-KITKLKTGTEYQFRIFAENRYGK 18115

Query: 986   SKPLTA-----QQTTKLDAPTNLQFVNE-TDSTVLVRWTPP----RAQITGYRLTVGLTR 1035
             S PL +     Q   K   P    FV   +   +LV+W  P      +I GY L      
Sbjct: 18116 SAPLDSKAVIVQYPFKEPGPPGTPFVTSISKDQMLVQWHEPVNDGGTKIIGYHLEQKEKN 18175

Query: 1036  RGQPRQYNVGP-SVSKYPLRNLQPASEYT--VSLVAIKGNQESPKATGVFTTLQPGSSIP 1092
                  + N  P   +K+    L    EY   VS   I G  +  K +  F    P    P
Sbjct: 18176 SILWVKLNKTPIQDTKFKTTGLDEGLEYEFKVSAENIVGIGKPSKVSECFVARDPCD--P 18233

Query: 1093  PYNTE---VTETTIVITWT-PAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVE 1148
             P   E   +T   + + W  PA   G K+     +  + P       G  + +  T  +E
Sbjct: 18234 PGRPEAIVITRNNVTLKWKKPAYDGGSKITGYIVEKKDLP------DGRWMKASFTNVLE 18287

Query: 1149  YVYTIQVLRDGQERDAPIVNK-VVTPLSPPT---------------NLHLEANPDTGVLT 1192
               +T+  L + Q  +  ++ +      S P+               N  L+      ++ 
Sbjct: 18288 TEFTVSGLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARDEIDAPNASLDPKYKDVIVV 18347

Query: 1193  VSWERSTTP-DITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLS---------PGLE 1242
              + E      DI G  I     + + G  LEE     +   T    +          G +
Sbjct: 18348 HAGETFVLEADIRGKPIPDVVWS-KDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQ 18406

Query: 1243  YNVSVYTVKDDKESVPISDTIIPAVPPPTD-LRFTNIGPDTMRVTWAPPPSIDLTNFLVR 1301
             Y + +  V   K S+PI+  ++    PP   L+ T +  +   + W PP      N    
Sbjct: 18407 YILKLSNVGGTK-SIPITVKVLDRPGPPEGPLKVTGVTAEKCYLAWNPPLQDGGANISHY 18465

Query: 1302  YSPVKNEEDVAELSISPSDNAV--VLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLD 1359
                 +    ++   +S    A+   +T LLPG EY+  V +V +     PL     T  +
Sbjct: 18466 IIEKRETSRLSWTQVSTEVQALNYKVTKLLPGNEYIFRVMAVNKYGIGEPLESGPVTACN 18525

Query: 1360  ------SPTGIDFSDITANSFTVHWIAP----RATITGYRIRHHPEHFSGRPREDRVPHS 1409
                    P+  + S IT +S  V W  P       I GY +    +      + ++   +
Sbjct: 18526 PYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDKEGVRWTKCNKKTLT 18585

Query: 1410  RNSITLTNLTPGTEYVVSIVALN----GREESPLLIGQQSTV---SDVPRDLEVVAATPT 1462
                + +T LT G  Y   + A N    G    P +  +          P + +V   + +
Sbjct: 18586 DLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRACDALYPPGPPSNPKVTDTSRS 18645

Query: 1463  SLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTA-----------------TI 1505
             S+ ++W  P               G +PV+ + V   ++ A                 T+
Sbjct: 18646 SVSLAWSKPIY------------DGGAPVKGYVVEVKEAAADEWTTCTPPTGLQGKQFTV 18693

Query: 1506  SGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPS 1565
             + LK   +Y   + A+   G    ++ P S+  +  I+ P      D++     V  L +
Sbjct: 18694 TKLKENTEYNFRICAINSEGVGEPATLPGSVVAQERIEPPEIELDADLR----KVVVLRA 18749

Query: 1566  SSPVTGYRVTTTPKNGPGP----TKTKTAGPD--QTEMTIEGLQPTVEYVV-------SV 1612
             S+ +   R+  T K  P P     K +    D  Q E+T       ++ V        ++
Sbjct: 18750 SATL---RLFVTIKGRPEPEVKWEKAEGILTDRAQIEVTSSFTMLVIDNVTRFDSGRYNL 18806

Query: 1613  YAQNPSGESQPLVQTAVTNI-DRPKGLAFTDVDVDSIKIAWESP----QGQVSRYRVTYS 1667
               +N SG     V   V +    P  L   +V  DS+ ++WE P      +++ Y V   
Sbjct: 18807 TLENNSGSKTAFVNVRVLDSPSAPVNLTIREVKKDSVTLSWEPPLIDGGAKITNYIVEKR 18866

Query: 1668  SPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPT- 1726
                   +      +  + T  ++ L+ G  Y   V+A ++     P   T+   +  P  
Sbjct: 18867 ETTRKAYATI-TNNCTKTTFRIENLQEGCSYYFRVLASNEYGIGLPAETTEPVKVSEPPL 18925

Query: 1727  ---DLKFTQVTPTSLSAQWTPP----NVQLTGYRVRVTPK--EKTGPMKEINLAPDSSSV 1777
                 +    VT  + + +W  P      ++TGY V +  K  EK     ++     +   
Sbjct: 18926 PPGRVTLVDVTRNTATIKWEKPESDGGSKITGYVVEMQTKGSEKWSTCTQVK----TLEA 18981

Query: 1778  VVSGLMVATKYEVSVYALKDTLTSRPAQ-GVVTTLENVS-------PPRRARVTDATETT 1829
              +SGL    +Y   V A+ +   S P Q GV     ++        P     V    +  
Sbjct: 18982 TISGLTAGEEYVFRVAAVNEKGRSDPRQLGVPVIARDIEIKPSVELPFHTFNVKAREQLK 19041

Query: 1830  ITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQ----PGTDYKIYLYT 1885
             I + ++ + +    ++ D     GQT  + T      S T+T L        D   Y   
Sbjct: 19042 IDVPFKGRPQATVNWRKD-----GQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELC 19096

Query: 1886  LNDNARS--SPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEK 1939
             ++++A S   P+ I        P  +R    + +S+ +SW PP      +I+ YI++ ++
Sbjct: 19097 VSNSAGSITVPITIIVLDRPGPPGPIRIDEVSCDSITISWNPPEYDGGCQISNYIVEKKE 19156

Query: 1940  PGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKS 1982
               S    +V +     T   I  L  G+EY   V A     KS
Sbjct: 19157 TTSTTWHIVSQ-AVARTSIKIVRLTTGSEYQFRVCAENRYGKS 19198



 Score =  118 bits (295), Expect = 8e-26
 Identities = 287/1359 (21%), Positives = 491/1359 (36%), Gaps = 205/1359 (15%)

Query: 780   LLPGRKYI-----VNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRP 834
             ++ G +YI     VN Y I E  E   +++ +    P  P  P V ++   S+ V WSRP
Sbjct: 20658 IIKGNEYIFRVRAVNKYGIGEPLESDSVVAKNAFVTPGPPGIPEVTKITKNSMTVVWSRP 20717

Query: 835   QA----PITGYRIVYSPSVEGSSTEL---NLPETANSVTLSDLQPGVQYNI-TIYAVEEN 886
              A     I+GY +           ++    + +T   VT        QY +  + A  + 
Sbjct: 20718 IADGGSDISGYFLEKRDKKSLGWFKVLKETIRDTRQKVTGLTENSDYQYRVCAVNAAGQG 20777

Query: 887   QESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVI 942
               S P    +        D    P  ++  + T   +T+ W+ P     SAVTGY V++ 
Sbjct: 20778 PFSEP---SEFYKAADPIDPPGPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVVEI- 20833

Query: 943   PVNLPGEHGQRLPIS-----RNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTK- 996
                  GE  +   +S     R T   V+ L PGV YYF+V AV+   + +P+   +  + 
Sbjct: 20834 ---RQGEEEEWTTVSTKGEVRTTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQA 20890

Query: 997   ---LDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQP--------RQYNVG 1045
                L+AP       E D  V +R T   A+  G  + V +  +G+P         + N+G
Sbjct: 20891 KDILEAP-------EIDLDVALR-TSVIAK-AGEDVQVLIPFKGRPPPTVTWRKDEKNLG 20941

Query: 1046  PSVSKYPLRNLQPASEYTVS----------LVAIKGNQESPKATGVFTTL--QPGSSIPP 1093
              S ++Y + N   +S  T+           ++ I+     PK++ V   +   P +    
Sbjct: 20942 -SDARYSIENTDSSSLLTIPQVTRNDTGKYILTIENGVGEPKSSTVSVKVLDTPAACQKL 21000

Query: 1094  YNTEVTETTIVITWTP------APRIGFKLGVRPS---QGGEAPREVTSDSGSIV-VSGL 1143
                 V+  T+ + W P      +P I + +  R +          + +S S  ++ +S  
Sbjct: 21001 QVKHVSRGTVTLLWDPPLIDGGSPIINYVIEKRDATKRTWSVVSHKCSSTSFKLIDLSEK 21060

Query: 1144  TPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDI 1203
             TP    V     +  G+  +     K     +P  +L ++ +  T V+ +SW   T PD 
Sbjct: 21061 TPFFFRVLAENEIGIGEPCETTEPVKAAEVPAPIRDLSMKDSTKTSVI-LSW---TKPDF 21116

Query: 1204  TGYRITTTPTNGQQGNSLEEVVHADQS-SCTFD----NLSPGLEYNVSVYTVKDDKESVP 1258
              G  + T     ++G   +   HA  S +C  +         LE+ V     K   + V 
Sbjct: 21117 DGGSVITEYVVERKGKGEQTWSHAGISKTCEIEVSQLKEQSVLEFRVFAKNEKGLSDPVT 21176

Query: 1259  ISDTIIP--AVPPPTDLRFTNIGPDTMRV----------TWAPPPSIDLTNFLVRYSPVK 1306
             I    +    + P  DL        T+R+             P PSI   ++L    P+K
Sbjct: 21177 IGPITVKELIITPEVDLSDIPGAQVTVRIGHNVHLELPYKGKPKPSI---SWLKDGLPLK 21233

Query: 1307  NEEDVAELSISPSDNAVVLT----NLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPT 1362
               E V     S ++N + L+        G +Y V + +      + P+          P 
Sbjct: 21234 ESEFV---RFSKTENKITLSIKNAKKEHGGKYTVILDNAV-CRIAVPITVITLGPPSKPK 21289

Query: 1363  G-IDFSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTN 1417
             G I F +I A+S  + W  P       IT Y I    E      +      +R +  + N
Sbjct: 21290 GPIRFDEIKADSVILSWDVPEDNGGGEITCYSIEKR-ETSQTNWKMVCSSVARTTFKVPN 21348

Query: 1418  LTPGTEYVVSIVALNGREESPLLIG------QQSTVSDVPRDLEVVAATPTSLLISWDAP 1471
             L    EY   + A N    S  L+        Q  +   P    +   T   + ++WDAP
Sbjct: 21349 LVKDAEYQFRVRAENRYGVSQPLVSSIIVAKHQFRIPGPPGKPVIYNVTSDGMSLTWDAP 21408

Query: 1472  AV----TVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDS 1527
                    V  + +   E       +  T P S      +GL  G+DY   VYA    G S
Sbjct: 21409 VYDGGSEVTGFHVEKKERNSILWQKVNTSPISGREYRATGLVEGLDYQFRVYAENSAGLS 21468

Query: 1528  PASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLP----SSSPVTGYRVTTTPKNGPG 1583
               S         + +D P      DV   +I++KW P      S + GY +     N   
Sbjct: 21469 SPSDPSKFTLAVSPVDPPGTPDYIDVTRETITLKWNPPLRDGGSKIVGYSIEKRQGNERW 21528

Query: 1584  PTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQN------PSGESQPLVQTAVTNIDRPKG 1637
               +       + + T+ GL P   Y   + A+N      P  +S  ++ T   N+  P  
Sbjct: 21529 -VRCNFTDVSECQYTVTGLSPGDRYEFRIIARNAVGTISPPSQSSGIIMTRDENV--PPI 21585

Query: 1638  LAFTDVDVDSI--------------------KIAWESPQGQVSRYRVTYSSPEDGIHELF 1677
             + F     D +                    ++ W     ++ +      +   G   LF
Sbjct: 21586 VEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLF 21645

Query: 1678  PAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTS 1737
                   + T + +G+     YTV         +++  +  Q T       ++FT +T   
Sbjct: 21646 V----RDATRDHRGV-----YTVEAKNASGSAKAEIKVKVQDTPGKVVGPIRFTNITGEK 21696

Query: 1738  LSAQWTPP-NVQLTGYRVRVTPKEKTGPM--KEINLAPDSSSVVVSGLMVATKYEVSVYA 1794
             ++  W  P N         +  K +T  +    I    ++ S     L+   +Y+  V A
Sbjct: 21697 MTLWWDAPLNDGCAPITHYIIEKRETSRLAWALIEDKCEAQSYTAIKLINGNEYQFRVSA 21756

Query: 1795  LKDTLTSRP--AQGVVTTLENVSP--PRRARVTDATETTITISWRTKTETITGFQVDA-- 1848
             +      RP  +  VV  ++   P  P     ++ T  +IT++W  + E+  G ++    
Sbjct: 21757 VNKFGVGRPLDSDPVVAQIQYTVPDAPGIPEPSNITGNSITLTW-ARPESDGGSEIQQYI 21815

Query: 1849  -----------VPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVI 1897
                        V    + PI  T       + +TGL  G +Y+ ++  + +NA       
Sbjct: 21816 LERREKKSTRWVKVISKRPISET------RFKVTGLTEGNEYEFHV--MAENAAGVGPAS 21867

Query: 1898  DASTAIDA---------PSNLRFLATTPNSLLVSWQPP----RARITGYIIKYEKPGSPP 1944
               S  I           P+ ++   T+  ++ + W  P       I GYII+  K     
Sbjct: 21868 GISRLIKCREPVNPPGPPTVVKVTDTSKTTVSLEWSKPVFDGGMEIIGYIIEMCKADLGD 21927

Query: 1945  REVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSE 1983
                V       T  T+T L+ G EY   V A+    K +
Sbjct: 21928 WHKVNAEACVKTRYTVTDLQAGEEYKFRVSAINGAGKGD 21966



 Score =  117 bits (294), Expect = 1e-25
 Identities = 275/1247 (22%), Positives = 460/1247 (36%), Gaps = 215/1247 (17%)

Query: 908   PSP-RDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTG 966
             P P R+L+ V+V+  + T+ W PPE    G  +     N   E  +   +  +T++  T 
Sbjct: 11925 PGPVRNLKIVDVSSDRCTVCWDPPEDD-GGCEIQ----NYILEKCETKRMVWSTYS-ATV 11978

Query: 967   LSPGVT---------YYFKVFA-----VSHGRESKPLTAQQTTKLDA-----PTNLQFVN 1007
             L+PG T         Y F+V A          ESKP+ A+  TK D      P  +  V+
Sbjct: 11979 LTPGTTVTRLIEGNEYIFRVRAENKIGTGPPTESKPVIAK--TKYDKPGRPDPPEVTKVS 12036

Query: 1008  ETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSV---SKYPLRNLQPAS 1060
             + + TV+  W PP       ITGY L      +   R   V  S     +  ++NL P  
Sbjct: 12037 KEEMTVV--WNPPEYDGGKSITGYFLE--KKEKHSTRWVPVNKSAIPERRMKVQNLLPDH 12092

Query: 1061  EYTVSLVAIK----GNQESPKATGVF-TTLQPGSSIPPYNTEVTETT---IVITWTP--- 1109
             EY   + A      G    P    V    ++P    PP N  V +TT   I + W     
Sbjct: 12093 EYQFRVKAENEIGIGEPSLPSRPVVAKDPIEPPG--PPTNFRVVDTTKHSITLGWGKPVY 12150

Query: 1110  ---APRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPI 1166
                AP IG+ + +RP     +P     D G    +     V   +T+  L + QE +  +
Sbjct: 12151 DGGAPIIGYVVEMRPKIADASP-----DEGWKRCNAAAQLVRKEFTVTSLDENQEYEFRV 12205

Query: 1167  VNKVVTPLSPPTNLHLEANP-----------DTGVLTVSWERSTTPD--ITGYRITTTPT 1213
               +    +  P  L     P           D  +  +   R+  P       R    P 
Sbjct: 12206 CAQNQVGIGRPAELKEAIKPKEILEPPEIDLDASMRKLVIVRAGCPIRLFAIVRGRPAPK 12265

Query: 1214  NGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDD-------------KESVPIS 1260
                +   ++ VV   Q      +L   + + V   + +DD             +++V ++
Sbjct: 12266 VTWRKVGIDNVVRKGQV-----DLVDTMAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFVN 12320

Query: 1261  DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELS-ISP- 1318
               ++    P +DL+ +++   +  V+WAPP + D  + +  Y   K E D    S ++P 
Sbjct: 12321 VRVLDTPGPVSDLKVSDVTKTSCHVSWAPPEN-DGGSQVTHYIVEKREADRKTWSTVTPE 12379

Query: 1319  -SDNAVVLTNLLPGTEYVVSVSSVYEQHESTP-------LRGRQKTGLDSPTGIDFSDIT 1370
                 +  +TNL+PG EY   V++V E     P       L     +  D P  ++ +++T
Sbjct: 12380 VKKTSFHVTNLVPGNEYYFRVTAVNEYGPGVPTDVPKPVLASDPLSEPDPPRKLEVTEMT 12439

Query: 1371  ANSFTVHWIAP----RATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVV 1426
              NS T+ W+ P     A I GY   +  E        +       S+ +T L  G +Y  
Sbjct: 12440 KNSATLAWLPPLRDGGAKIDGYITSYREEEQPADRWTEYSVVKDLSLVVTGLKEGKKYKF 12499

Query: 1427  SIVALNGREESPLLIGQQSTVSDVPRDLEVV-----AATPTSLLISWDAPAVTVRYYRIT 1481
              + A N    S            +PR+ E V        P  +L+         +  RI 
Sbjct: 12500 RVAARNAVGVS------------LPREAEGVYEAKEQLLPPKILMPEQITIKAGKKLRIE 12547

Query: 1482  YGETGGNSPV------QEFTVPGS------KSTATISGLKPGVDYTITVYAVTGRGDSPA 1529
                 G   P       ++  V  S        +++I  +K         Y++T    S  
Sbjct: 12548 AHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGYYSLTAENSSGT 12607

Query: 1530  SSKPISINYRTEIDKPSQMQ----VTDVQDNSISVKW-LP---SSSPVTGYRVTTTPKNG 1581
              ++ I +     +D P   Q    ++D+  ++ S+ W +P     S +T Y V     + 
Sbjct: 12608 DTQKIKV---VVMDAPGPPQPPFDISDIDADACSLSWHIPLEDGGSNITNYIVEKCDVS- 12663

Query: 1582  PGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTN------IDRP 1635
              G   T  A   +T   +  L P  EY+  V A+N  G S+PL    +           P
Sbjct: 12664 RGDWVTALASVTKTSCRVGKLIPGQEYIFRVRAENRFGISEPLTSPKMVAQFPFGVPSEP 12723

Query: 1636  KGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELF--PAPDGEEDTAE--LQG 1691
             K    T V+ D I +AW+ P        + Y       + L    A D    + E    G
Sbjct: 12724 KNARVTKVNKDCIFVAWDRPDSDGGSPIIGYLIERKERNSLLWVKANDTLVRSTEYPCAG 12783

Query: 1692  LRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTD----LKFTQVTPTSLSAQWTPP-- 1745
             L  G EY+  + AL+    S P   T+      P D     +   VT +++S  W  P  
Sbjct: 12784 LVEGLEYSFRIYALNKAGSSPPSKPTEYVTARMPVDPPGKPEVIDVTKSTVSLIWARPKH 12843

Query: 1746  --NVQLTGYRVRVTPKEKTGPMKEINLAP---DSSSVVVSGLMVATKYE---VSVYALKD 1797
                 ++ GY V    K         N AP          +GL    +Y+   ++  A+  
Sbjct: 12844 DGGSKIIGYFVEAC-KLPGDKWVRCNTAPHQIPQEEYTATGLEEKAQYQFRAIARTAVNI 12902

Query: 1798  TLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKT---ETITGFQVDAV----- 1849
             +  S P+  V    ENV P  R  ++ A ++ +T+   T      T+ G  +  V     
Sbjct: 12903 SPPSEPSDPVTILAENVPP--RIDLSVAMKSLLTVKAGTNVCLDATVFGKPMPTVSWKKD 12960

Query: 1850  -----PANG-QTPIQRTI---------KPDVRSYTITGLQPGTDYKIYLYTLNDNARSSP 1894
                  PA G +  +QR +         + D   YTIT               +  ++S+ 
Sbjct: 12961 GTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTITAEN------------SSGSKSAT 13008

Query: 1895  VVIDASTAIDAPSNLRFLATTPNSLLVSWQPP----RARITGYIIKYEKPGSPPREVVPR 1950
             + +        P++++      +  ++SW+PP     + IT YI+   +   P    V  
Sbjct: 13009 IKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYIVDKRETSRPNWAQVSA 13068

Query: 1951  PRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQKTPF 1997
               P +T  ++  L  G EY   + A       +P+   +  + K P+
Sbjct: 13069 TVP-ITSCSVEKLIEGHEYQFRICAENKYGVGDPVF-TEPAIAKNPY 13113



 Score =  117 bits (293), Expect = 1e-25
 Identities = 324/1541 (21%), Positives = 541/1541 (35%), Gaps = 222/1541 (14%)

Query: 612  VEVFITETPSQPNSHPIQ----------WNAPQP---SHISKYILRWRPKNSVGRWKEAT 658
            VEV + + P  P +  I           WN P+    S I+ Y++  R  +S   W + +
Sbjct: 7404 VEVNVLDKPGPPAAFDITDVTNESCLLTWNPPRDDGGSKITNYVVERRATDSEV-WHKLS 7462

Query: 659  IPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPF 718
                  ++    L P   Y  ++ +   YG  E             PV ++ +T +    
Sbjct: 7463 STVKDTNFKATKLIPNKEYIFRVAAENMYGVGE-------------PVQASPITAKYQFD 7509

Query: 719  SPLVATSESVTEITASSFVVSWVSASDT----VSGFRVEYELSEEGDEPQYLDLPSTATS 774
             P   T    ++IT  +  ++W    D     ++G+ VE    +     +   +P   T+
Sbjct: 7510 PPGPPTRLEPSDITKDAVTLTWCEPDDDGGSPITGYWVERLDPDTDKWVRCNKMPVKDTT 7569

Query: 775  VNIPDLLPGRKYIVNVY--QISEDGEQSL----ILSTSQTTAPDAPPDPTVDQVDDTSIV 828
              +  L   +KY   V    ++  G+ S     IL       P  P  PTV  V  TS+ 
Sbjct: 7570 YRVKGLTNKKKYRFRVLAENLAGPGKPSKSTEPILIKDPIDPPWPPGKPTVKDVGKTSVR 7629

Query: 829  VRWSRPQ----APITGY--RIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYA 882
            + W++P+    A I  Y   ++ + + E       +P T +   L  L  G +Y+  + A
Sbjct: 7630 LNWTKPEHDGGAKIESYVIEMLKTGTDEWVRVAEGVPTTQH--LLPGLMEGQEYSFRVRA 7687

Query: 883  VEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYR 938
            V +  ES P           +      PR L+ + +T     + WT PE    S +T Y 
Sbjct: 7688 VNKAGESEPSEPSDPVLCREKLYPPSPPRWLEVINITKNTADLKWTVPEKDGGSPITNYI 7747

Query: 939  VDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSH-GR------ESKPLTA 991
            V+   V   G       + ++T   VT L+ G  Y F+V A +  G+      E   L  
Sbjct: 7748 VEKRDVRRKGWQTVDTTV-KDTKCTVTPLTEGSLYVFRVAAENAIGQSDYTEIEDSVLAK 7806

Query: 992  QQTTKLDAPTNLQFVNETDSTVLVRWTPPR--AQITGYRLTVGLTRRGQPRQYNVGPSVS 1049
               T    P  L  V+ T   V ++W PP+        R  +    R   R    G +  
Sbjct: 7807 DTFTTPGPPYALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKERLGTRWVKAGKTAG 7866

Query: 1050 KYPLRNLQPASEYTVSLVAIKGNQES-----PKATGVFTTLQPGS-SIPPYNTEVTET-- 1101
                  +    E T     ++   E+      + T + +   P S   PP +  VT+   
Sbjct: 7867 PDCNFRVTDVIEGTEVQFQVRAENEAGVGHPSEPTEILSIEDPTSPPSPPLDLHVTDAGR 7926

Query: 1102 -TIVITWTP------APRIGFKLGVRPSQGGEAPREVTS----DSGSIVVSGLTPGVEYV 1150
              I I W P      +P IG+ + + P  G E    V S    D    V  G+ P  EYV
Sbjct: 7927 KHIAIAWKPPEKNGGSPIIGYHVEMCP-VGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYV 7985

Query: 1151 YTIQVLRD-GQERDAPIVNKVVT--PLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYR 1207
              ++ +   G    + I   VV   P   PT + LE +    ++ +  E+ + P    +R
Sbjct: 7986 LRVRAVNAIGVSEPSEISENVVAKDPDCKPT-IDLETH---DIIVIEGEKLSIP--VPFR 8039

Query: 1208 ITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEY------NVSVYTV----KDDKESV 1257
                PT     +  +EV  +D+ +   D++S  LE       +  +YT+    K    + 
Sbjct: 8040 AVPVPTVSWHKDG-KEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATA 8098

Query: 1258 PISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSIS 1317
             I+  +I    P  D++ ++I   + ++TW PP     T  L      +       + + 
Sbjct: 8099 SINVKVIGLPGPCKDIKASDITKSSCKLTWEPPEFDGGTPILHYVLERREAGRRTYIPVM 8158

Query: 1318 PSDNAVVLT--NLLPGTEYVVSVSSV-------YEQHESTPLRGRQKTGLDSPTGIDFSD 1368
              +N +  T  +L+P  EY   V +V       Y + ++  +    K   D P  ++  +
Sbjct: 8159 SGENKLSWTVKDLIPNGEYFFRVKAVNKVGGGEYIELKNPVIAQDPKQPPDPPVDVEVHN 8218

Query: 1369 ITANSFTVHWIAP----RATITGYRIRH--HPEHFSGRPREDRVPHSRNSITLTNLTPGT 1422
             TA + T+ W  P     + I GY I      E    R  E  VP    + T   L  G 
Sbjct: 8219 PTAEAMTITWKPPLYDGGSKIMGYIIEKIAKGEERWKRCNEHLVPIL--TYTAKGLEEGK 8276

Query: 1423 EYVVSIVALNGREESPLLIGQQSTVSDVPRDL-EVVAATPTSLL----ISWDAPAVTVRY 1477
            EY   + A N    S        T +  P D  +V+  T   +     I+ DA      Y
Sbjct: 8277 EYQFRVRAENAAGISEPSRATPPTKAVDPIDAPKVILRTSLEVKRGDEIALDASISGSPY 8336

Query: 1478 YRITY------------------------GETGGNSP-----VQEFTVPGSKSTATISGL 1508
              IT+                        GE     P      Q  ++  SK   +   +
Sbjct: 8337 PTITWIKDENVIVPEEIKKRAAPLVRRRKGEVQEEEPFVLPLTQRLSIDNSKKGESQLRV 8396

Query: 1509 KPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLP---- 1564
            +  +     +Y +    D   +  P +++       P      D++  S+  KW P    
Sbjct: 8397 RDSLRPDHGLYMIKVENDHGIAKAPCTVSVLDTPGPPINFVFEDIRKTSVLCKWEPPLDD 8456

Query: 1565 SSSPVTGYRVTTTPKNGP-GPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQP 1623
              S +  Y +    K  P       T+     + ++  L    EY+  V A+N  G   P
Sbjct: 8457 GGSEIINYTLEKKDKTKPDSEWIVVTSTLRHCKYSVTKLIEGKEYLFRVRAENRFGPGPP 8516

Query: 1624 LVQTAVT------NIDRPKGLAFTDVDVDSIKIAWESPQ-------GQVSRYRVTYSSPE 1670
             V   +         D P      DV  +S+ + W  P+       G     R   S+  
Sbjct: 8517 CVSKPLVAKDPFGPPDAPDKPIVEDVTSNSMLVKWNEPKDNGSPILGYWLEKREVNSTHW 8576

Query: 1671 DGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHD------DMESQPLIGTQSTAIPA 1724
              +++           A + GL  G  Y   V A +          S P       + P 
Sbjct: 8577 SRVNKSLL----NALKANVDGLLEGLTYVFRVCAENAAGPGKFSPPSDPKTAHDPISPPG 8632

Query: 1725 PTDLKFTQVTPTSLSAQWTPP----NVQLTGYRVRVTPKEKTGPMKEINLAPDSSSV--- 1777
            P   + T  + T++  +W PP      ++ GY V    K+  G  +          V   
Sbjct: 8633 PPIPRVTDTSSTTIELEWEPPAFNGGGEIVGYFV---DKQLVGTNEWSRCTEKMIKVRQY 8689

Query: 1778 VVSGLMVATKYEVSVYALKDTLTSRPAQ-GVVTTLENVSPPRRARVTDATETTITISWRT 1836
             V  +     Y++ V A+       P +   VT  E   PP       A E  +++    
Sbjct: 8690 TVKEIREGADYKLRVSAVNAAGEGPPGETQPVTVAEPQEPP-------AVELDVSVKGGI 8742

Query: 1837 KTETITGFQVDAVPANGQTPIQRTIKPD--------------VRSYTITGLQPGTDYKIY 1882
            +       ++ AV      P +   K +               +S  I       D+  Y
Sbjct: 8743 QIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKDRVVIDNVGTKSELIIKDALRKDHGRY 8802

Query: 1883 LYTLNDNARSSPVVIDASTAIDAPS---NLRFLATTPNSLLVSWQPPR----ARITGYII 1935
            + T   N+  S          D P    +L+ + T     L++W  P     + ITG+II
Sbjct: 8803 VITAT-NSCGSKFAAARVEVFDVPGPVLDLKPVVTNRKMCLLNWSDPEDDGGSEITGFII 8861

Query: 1936 KYEKPGSPP-REVVPRPRPGVTEATITGLEPGTEYTIYVIA 1975
            + +       R+ +   R   ++  ITGL  G EY   VIA
Sbjct: 8862 ERKDAKMHTWRQPIETER---SKCDITGLLEGQEYKFRVIA 8899



 Score =  117 bits (293), Expect = 1e-25
 Identities = 292/1326 (22%), Positives = 488/1326 (36%), Gaps = 202/1326 (15%)

Query: 811   PDAPPDPT-VDQVDDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSV 865
             P  P  P   + V    + + W  P+    + IT Y I    +   +   ++      + 
Sbjct: 9845  PGPPVGPIKFESVSADQMTLSWFPPKDDGGSKITNYVIEKREANRKTWVHVSSEPKECTY 9904

Query: 866   TLSDLQPGVQYNITIYAVEENQESTPVVIQQETT-------GTPRSDTVPSPRDLQFVEV 918
             T+  L  G +Y   I A  +     P+  + ET        G P   TV S        V
Sbjct: 9905  TIPKLLEGHEYVFRIMAQNKYGIGEPLDSEPETARNLFSVPGAPDKPTVSS--------V 9956

Query: 919   TDVKVTIMWTPPE----SAVTGYRVDVIPVNLPG-EHGQRLPISRNTFA---EVTGLSPG 970
             T   +T+ W  PE    S VTGY +++        +   R PI   T     +VTGL  G
Sbjct: 9957  TRNSMTVNWEEPEYDGGSPVTGYWLEMKDTTSKRWKRVNRDPIKAMTLGVSYKVTGLIEG 10016

Query: 971   VTYYFKVFAVSHGR------ESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPR--- 1021
               Y F+V+A++          S P TA+       P   +  + T S+  + W+PP    
Sbjct: 10017 SDYQFRVYAINAAGVGPASLPSDPATARDPIAPPGPPFPKVTDWTKSSADLEWSPPLKDG 10076

Query: 1022  -AQITGYRLTVGLTRRGQPRQYNVGPSV----SKYPLRNLQPASEYT--VSLVAIKGNQE 1074
              +++TGY   V     G+  ++  G       +K  +  L+  + Y   V  V I G  E
Sbjct: 10077 GSKVTGY--IVEYKEEGK-EEWEKGKDKEVRGTKLVVTGLKEGAFYKFRVRAVNIAGIGE 10133

Query: 1075  SPKATGVFTT--------LQPGSSIPP----YNTEVTETTIVITWTPAPRIGFKLGVRPS 1122
               + T V           LQ  +S+      +   V      ++  P P + + +  R +
Sbjct: 10134 PGEVTDVIEMKDRLVSPDLQLDASVRDRIVVHAGGVIRIIAYVSGKPPPTVTWNMNER-T 10192

Query: 1123  QGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVT---PLSPPTN 1179
                EA  E T+ S S+V+       + VY++    +  ER   I+  V+    P+  P  
Sbjct: 10193 LPQEATIETTAISSSMVIKNCQRSHQGVYSLLAKNEAGERKKTIIVDVLDVPGPVGTPFL 10252

Query: 1180  LHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSP 1239
              H   N    +   S E      IT Y I    ++ +    +   V   + + T   L  
Sbjct: 10253 AHNLTNESCKLTWFSPEDDGGSPITNYVIEKRESDRRAWTPVTYTV--TRQNATVQGLIQ 10310

Query: 1240  GLEY--------NVSVYTVKDDKESVPISDTIIPAVPP-PTDLRFTNIGPDTMRVTWAPP 1290
             G  Y        ++ +    +  E++ I + I   VP  P DL    +  +T+ +TW PP
Sbjct: 10311 GKAYFFRIAAENSIGMGPFVETSEALVIREPI--TVPERPEDLEVKEVTKNTVTLTWNPP 10368

Query: 1291  P---SIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHES 1347
                   ++ N+++    +  E+     + +       +  L  G  Y   VS+V    + 
Sbjct: 10369 KYDGGSEIINYVLESRLIGTEKFHKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQG 10428

Query: 1348  TPLRGRQ----KTGLDSPT-GIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPR 1402
              P    +    K  L  PT  +DF D      T+  +     +TG         +SG+P+
Sbjct: 10429 KPSFCTKPITCKDELAPPTLHLDFRD----KLTIR-VGEAFALTG--------RYSGKPK 10475

Query: 1403  ------EDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQST--------VS 1448
                   +D      +  T    TP T  +  I A         ++ + ST        V+
Sbjct: 10476 PKVSWFKDEADVLEDDRTHIKTTPATLALEKIKAKRSDSGKYCVVVENSTGSRKGFCQVN 10535

Query: 1449  DVPRDLEVVA------ATPTSLLISWDAP----AVTVRYYRITYGETGGN--SPVQEFTV 1496
              V R    V        T   ++ISW  P       +  Y I   E G +   PV   T 
Sbjct: 10536 VVDRPGPPVGPVSFDEVTKDYMVISWKPPLDDGGSKITNYIIEKKEVGKDVWMPV---TS 10592

Query: 1497  PGSKSTATISGLKPGVDYTITVYAVTGRGDS-PASSKPISINYRTEI-DKPSQMQVTDVQ 1554
               +K+T  +S L  G DY   ++A    G S P  S  +    R  + D P Q  VT+V 
Sbjct: 10593 ASAKTTCKVSKLLEGKDYIFRIHAENLYGISDPLVSDSMKAKDRFRVPDAPDQPIVTEVT 10652

Query: 1555  DNSISVKWLP---SSSPVTGY---RVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEY 1608
              +S  V W        P+T Y   +  T  K     TK        T+  +  L    +Y
Sbjct: 10653 KDSALVTWNKPHDGGKPITNYILEKRETMSKRWARVTKDPIH--PYTKFRVPDLLEGCQY 10710

Query: 1609  VVSVYAQN------PSGESQPL-VQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQ----G 1657
                V A+N      PS  S+P+  +  +     P      D   +S+ + W+ P+     
Sbjct: 10711 EFRVSAENEIGIGDPSPPSKPVFAKDPIAKPSPPVNPEAIDTTCNSVDLTWQPPRHDGGS 10770

Query: 1658  QVSRYRVTYSSPEDGI-HELFPAPDGEEDTA-ELQGLRPGSEYTVSVVALHDDMESQPLI 1715
             ++  Y V Y    D         P+   +T  ++ GLR G  Y   V+A++   ES P  
Sbjct: 10771 KILGYIVEYQKVGDEEWRRANHTPESCPETKYKVTGLRDGQTYKFRVLAVNAAGESDP-- 10828

Query: 1716  GTQSTAIPAPTDLKFTQVTP-TSLSAQWTPPNVQLTGYRVRVT------PKEKTGPMKEI 1768
                   +P P  +K     P   L A          G  +R++      P  K    KE 
Sbjct: 10829 ----AHVPEPVLVKDRLEPPELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKED 10884

Query: 1769  NLAPDSSSVVVSGLMVATKYEV--------SVYAL--KDTLTSRPAQGVVTTLENVSPPR 1818
               AP  + + V+   V +K E+         +Y+L  ++   S+     V  L+   PPR
Sbjct: 10885 RDAPTKARIDVT--PVGSKLEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDKPGPPR 10942

Query: 1819  RARVTDATETTITISWRTKTE----TITGFQVDA--VPANGQTPIQRTIKPDVRSYTITG 1872
                V++  + +  ++W+   +     IT + V+   V +   +P+  T K   +S+    
Sbjct: 10943 DLEVSEIRKDSCYLTWKEPLDDGGSVITNYVVERRDVASAQWSPLSATSKK--KSHFAKH 11000

Query: 1873  LQPGTDYKIYLYTLNDNARSSPV-------VIDASTAIDAPSNLRFLATTPNSLLVSWQP 1925
             L  G  Y   +   N   R   V        +D       P +L  +      + + W  
Sbjct: 11001 LNEGNQYLFRVAAENQYGRGPFVETPKPIKALDPLHPPGPPKDLHHVDVDKTEVSLVWNK 11060

Query: 1926  P----RARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQK 1981
             P     + ITGY+++Y++ G+  ++ +        E  +TGL+ G  Y   V       K
Sbjct: 11061 PDRDGGSPITGYLVEYQEEGT--QDWIKFKTVTNLECVVTGLQQGKTYRFRV-------K 11111

Query: 1982  SEPLIG 1987
             +E ++G
Sbjct: 11112 AENIVG 11117



 Score =  114 bits (286), Expect = 9e-25
 Identities = 268/1373 (19%), Positives = 504/1373 (36%), Gaps = 176/1373 (12%)

Query: 766  LDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDT 825
            +D  +  TS  I +   G K    +   ++ G+    ++      P    +  V +  D 
Sbjct: 6673 IDTTAEQTSFRILEAKKGDKGRYKIVLQNKHGKAEGFINLKVIDVPGPVRNLEVTETFDG 6732

Query: 826  SIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETAN-SVTLSDLQPG-VQYNIT 879
             + + W  P     + I GY +V    ++  +  L      +   T++ LQ G V+Y   
Sbjct: 6733 EVSLAWEEPLTDGGSKIIGY-VVERRDIKRKTWVLATDRAESCEFTVTGLQKGGVEYLFR 6791

Query: 880  IYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVT 935
            + A        PV          + D    P ++   +V    V++ W PPE    + +T
Sbjct: 6792 VSARNRVGTGEPVETDNPVEARSKYDVPGPPLNVTITDVNRFGVSLTWEPPEYDGGAEIT 6851

Query: 936  GYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTT 995
             Y +++               + +  A VT +  G  Y F+V A +     KP  A    
Sbjct: 6852 NYVIELRDKTSIRWDTAMTVRAEDLSATVTDVVEGQEYSFRVRAQNRIGVGKPSAATPFV 6911

Query: 996  KL-------DAPTNLQFVNETDSTVLVRWTPP----RAQITGYRLTVGLTRRGQPR---- 1040
            K+         P NL   ++T S+V ++W PP     + I GY   +     G+      
Sbjct: 6912 KVADPIERPSPPVNLTSSDQTQSSVQLKWEPPLKDGGSPILGY--IIERCEEGKDNWIRC 6969

Query: 1041 QYNVGPSVSKYPLRNLQPASE--YTVSLVAIKGNQESPKATGVFTT----LQPGSSIPPY 1094
               + P ++ Y +  L+  ++  Y VS     G  +  +  G  T     ++P   +  +
Sbjct: 6970 NMKLVPELT-YKVTGLEKGNKYLYRVSAENKAGVSDPSEILGPLTADDAFVEPTMDLSAF 7028

Query: 1095 NTEV-----TETTIVI--TWTPAPRIGFKLGVRPSQGGEAPREVT-SDSGSIVVSGLTPG 1146
               +        TI++  T  P P   +  G +  + G+  +  T S    +V+S     
Sbjct: 7029 KDGLEVIVPNPITILVPSTGYPRPTATWCFGDKVLETGDRVKMKTLSAYAELVISPSERS 7088

Query: 1147 VEYVYTIQVLRDGQERDAPI-VNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPD--- 1202
             + +YT+++    +     I VN +  P +P      +   D+  LT  WE    PD   
Sbjct: 7089 DKGIYTLKLENRVKTISGEIDVNVIARPSAPKELKFGDITKDSVHLT--WE---PPDDDG 7143

Query: 1203 ---ITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEY--NVSVYTVKDDKESV 1257
               +TGY +     + +    + + V       T  +L  G EY   V         E  
Sbjct: 7144 GSPLTGYVVEKREVSRKTWTKVMDFV--TDLEFTVPDLVQGKEYLFKVCARNKCGPGEPA 7201

Query: 1258 PISDTIIPAVP-----PPTDLRFTNIGPDTMRVTWAPPPS---IDLTNFLVRYSPVKNEE 1309
             + + +  + P     PP ++++ +   +++ +TW PP +     +  ++V   P  +++
Sbjct: 7202 YVDEPVNMSTPATVPDPPENVKWRDRTANSIFLTWDPPKNDGGSRIKGYIVERCPRGSDK 7261

Query: 1310 DVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDI 1369
             VA      ++  + +T L  G  Y   V ++  Q  S P R  ++        +D  + 
Sbjct: 7262 WVA-CGEPVAETKMEVTGLEEGKWYAYRVKALNRQGASKPSRPTEEI-----QAVDTQEA 7315

Query: 1370 TANSFTVHWIAPRATITGYRIRHHPEHFSGRP-------REDRVPHSRNSITLTNLTPGT 1422
                  V  +A      G +I   P   +G+P       + D +      IT+ N+    
Sbjct: 7316 PEIFLDVKLLAGLTVKAGTKI-ELPATVTGKPEPKITWTKADMILKQDKRITIENVP--K 7372

Query: 1423 EYVVSIVALNGREESPLLI------GQQSTVSDV--------PRDLEVVAATPTSLLISW 1468
            +  V+IV     +    +I      G+ + V +V        P   ++   T  S L++W
Sbjct: 7373 KSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNVLDKPGPPAAFDITDVTNESCLLTW 7432

Query: 1469 DAP----AVTVRYYRITYGETGG------NSPVQEFTVPGSKSTATISGLKPGVDYTITV 1518
            + P       +  Y +    T        +S V++     +K       L P  +Y   V
Sbjct: 7433 NPPRDDGGSKITNYVVERRATDSEVWHKLSSTVKDTNFKATK-------LIPNKEYIFRV 7485

Query: 1519 YAVTGRG-DSPASSKPISINYRTE-IDKPSQMQVTDVQDNSISVKWL----PSSSPVTGY 1572
             A    G   P  + PI+  Y+ +    P++++ +D+  +++++ W        SP+TGY
Sbjct: 7486 AAENMYGVGEPVQASPITAKYQFDPPGPPTRLEPSDITKDAVTLTWCEPDDDGGSPITGY 7545

Query: 1573 RVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQP-------LV 1625
             V     +     +        T   ++GL    +Y   V A+N +G  +P       L+
Sbjct: 7546 WVERLDPDTDKWVRCNKMPVKDTTYRVKGLTNKKKYRFRVLAENLAGPGKPSKSTEPILI 7605

Query: 1626 QTAVTNIDRPKGLAFTDVDVDSIKIAWESPQ--GQVSRYRVTYSSPEDGIHELFPAPDGE 1683
            +  +     P      DV   S+++ W  P+  G            + G  E     +G 
Sbjct: 7606 KDPIDPPWPPGKPTVKDVGKTSVRLNWTKPEHDGGAKIESYVIEMLKTGTDEWVRVAEGV 7665

Query: 1684 EDTAE-LQGLRPGSEYTVSVVALHDDMESQ------PLIGTQSTAIPAPTD-LKFTQVTP 1735
              T   L GL  G EY+  V A++   ES+      P++  +    P+P   L+   +T 
Sbjct: 7666 PTTQHLLPGLMEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLEVINITK 7725

Query: 1736 TSLSAQWTPPNVQ----LTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVS 1791
             +   +WT P       +T Y V      + G  + ++     +   V+ L      E S
Sbjct: 7726 NTADLKWTVPEKDGGSPITNYIVEKRDVRRKG-WQTVDTTVKDTKCTVTPLT-----EGS 7779

Query: 1792 VYALKDTLTSRPAQGVVTTLEN----------VSPPRRARVTDATETTITISWRTKT--- 1838
            +Y  +    +   Q   T +E+            PP    V D T+  + + W       
Sbjct: 7780 LYVFRVAAENAIGQSDYTEIEDSVLAKDTFTTPGPPYALAVVDVTKRHVDLKWEPPKNDG 7839

Query: 1839 -ETITGFQVDAVPANGQTPIQ--RTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSP- 1894
               I  + ++     G   ++  +T  PD  ++ +T +  GT+ +  +   N+     P 
Sbjct: 7840 GRPIQRYVIEKKERLGTRWVKAGKTAGPDC-NFRVTDVIEGTEVQFQVRAENEAGVGHPS 7898

Query: 1895 ------VVIDASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPP 1944
                   + D ++    P +L         + ++W+PP     + I GY ++    G+  
Sbjct: 7899 EPTEILSIEDPTSPPSPPLDLHVTDAGRKHIAIAWKPPEKNGGSPIIGYHVEMCPVGTEK 7958

Query: 1945 -REVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQKTP 1996
               V  RP   +      G+ P  EY + V A+     SEP    +  V K P
Sbjct: 7959 WMRVNSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAIGVSEPSEISENVVAKDP 8011



 Score =  107 bits (266), Expect = 2e-22
 Identities = 292/1356 (21%), Positives = 513/1356 (37%), Gaps = 189/1356 (13%)

Query: 727   SVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQ--YLDLPSTA--TSVNIPDLLP 782
             +VTE+T+   V+SW    D   G ++++ + ++ +  +  + ++ S    T + +  LL 
Sbjct: 15191 AVTEVTSEKCVLSWFPPLDD-GGAKIDHYIVQKRETSRLAWTNVASEVQVTKLKVTKLLK 15249

Query: 783   GRKYI-----VNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAP 837
             G +YI     VN Y + E  E   +L+ +    PD P +P V  +   S+VV W  P + 
Sbjct: 15250 GNEYIFRVMAVNKYGVGEPLESEPVLAVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDS- 15308

Query: 838   ITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQ-------PGVQYNITIYAVEENQEST 890
               G   + +  VE            N  TL+DL+        G +Y   I A      S 
Sbjct: 15309 -DGGSEIINYIVERRDKAGQRWIKCNKKTLTDLRYKVSGLTEGHEYEFRIMAENAAGISA 15367

Query: 891   PVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNL 946
             P                  P + + ++ +   ++I W  P     S +TGY V++    L
Sbjct: 15368 PSPTSPFYKACDTVFKPGPPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIA---L 15424

Query: 947   PGEHGQRLPIS----RNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLD---A 999
             P E   ++       + T   +TGL+    Y  +++A++     +P     T K +    
Sbjct: 15425 PEEDEWQIVTPPAGLKATSYTITGLTENQEYKIRIYAMNSEGLGEPALVPGTPKAEDRML 15484

Query: 1000  PTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPR---QYNVGPSVSKYPLRNL 1056
             P  ++   +    V +R           RL V +  R  P      + G S+ K    ++
Sbjct: 15485 PPEIELDADLRKVVTIR------ACCTLRLFVPIKGRPAPEVKWARDHGESLDK---ASI 15535

Query: 1057  QPASEYTVSLVAIKGNQESPK----------ATGVFTTLQ----PGSSIPPYNTEVTETT 1102
             +  S YT+ +V      +S K          +   F  ++    PG        EVT+T+
Sbjct: 15536 ESTSSYTLLIVGNVNRFDSGKYILTVENSSGSKSAFVNVRVLDTPGPPQDLKVKEVTKTS 15595

Query: 1103  IVITWTPAPRI--GFKLGVRPSQGGEAPREVTS------DSGSIVVSGLTPGVEYVYTIQ 1154
             + +TW P P +  G K+     +  E+ R+  S         S  V  L  G  Y +  +
Sbjct: 15596 VTLTWDP-PLLDGGSKIKNYIVEKRESTRKAYSTVATNCHKTSWKVDQLQEGCSYYF--R 15652

Query: 1155  VLRDGQ------ERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPD---ITG 1205
             VL + +         A  V     PL P     ++   ++  +++SWE+        I G
Sbjct: 15653 VLAENEYGIGLPAETAESVKASERPLPPGKITLMDVTRNS--VSLSWEKPEHDGGSRILG 15710

Query: 1206  YRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYT-----VKDDKE-SVPI 1259
             Y I    T G    +    V   +++ T   L  G EY+  V       + D ++ SVP+
Sbjct: 15711 Y-IVEMQTKGSDKWATCATVKVTEATIT--GLIQGEEYSFRVSAQNEKGISDPRQLSVPV 15767

Query: 1260  --SDTIIPAVPPPTDLRFTNIGPDTMRV----TWAPPPSIDLTNFLVRYSPVKNEEDVAE 1313
                D +IP         FT +  + ++V       P P++      V   P+K       
Sbjct: 15768 IAKDLVIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNV---PLK---QTTR 15821

Query: 1314  LSISPSDNAVVLTNLLPGTE----YVVSV-SSVYEQHESTPLRGRQKTGLDSPTG-IDFS 1367
             ++   ++N  +LT      E    YVV + +S  E  E+  +    K G   PTG +   
Sbjct: 15822 VNAESTENNSLLTIKDACREDVGHYVVKLTNSAGEAIETLNVIVLDKPG--PPTGPVKMD 15879

Query: 1368  DITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTE 1423
             ++TA+S T+ W  P+    ++I  Y +    +  +   +      +R +I    L  G E
Sbjct: 15880 EVTADSITLSWGPPKYDGGSSINNYIVEKR-DTSTTTWQIVSATVARTTIKACRLKTGCE 15938

Query: 1424  YVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPT-------SLLISWDAP----A 1472
             Y   I A N   +S  L   + TV+  P  +     TP        S+ + W+ P     
Sbjct: 15939 YQFRIAAENRYGKSTYL-NSEPTVAQYPFKVPGPPGTPVVTLSSRDSMEVQWNEPISDGG 15997

Query: 1473  VTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSK 1532
               V  Y +   E      V+    P  ++    +GL+ GV+Y   V A    G    S  
Sbjct: 15998 SRVIGYHLERKERNSILWVKLNKTPIPQTKFKTTGLEEGVEYEFRVSAENIVGIGKPSKV 16057

Query: 1533  PISINYRTEIDKPSQMQVTDVQDNSISVKW----LPSSSPVTGYRVTTTPKNGPGPTKTK 1588
                   R   D P + +   V  NS++++W        S +TGY V           K  
Sbjct: 16058 SECYVARDPCDPPGRPEAIIVTRNSVTLQWKKPTYDGGSKITGYIVEKKELPEGRWMKAS 16117

Query: 1589  TAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE-SQPLVQT-AVTNIDR--PKGLAFTDVD 1644
                   T   + GL     Y   V A+N +G  S+P   T A+T  D   P  ++     
Sbjct: 16118 FTNIIDTHFEVTGLVEDHRYEFRVIARNAAGVFSEPSESTGAITARDEVDPPRISMDPKY 16177

Query: 1645  VDSIKI-AWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVV 1703
              D+I + A ES +         Y  P   I  +     G+++ +    L   S    + +
Sbjct: 16178 KDTIVVHAGESFKVDAD----IYGKPIPTIQWI----KGDQELSNTARLEIKSTDFATSL 16229

Query: 1704  ALHDD---------MESQPLIGTQSTAI-------PAPTD--LKFTQVTPTSLSAQWTPP 1745
             ++ D          ++++ + G +S  +       P P +  +  + VT    +  W PP
Sbjct: 16230 SVKDAVRVDSGNYILKAKNVAGERSVTVNVKVLDRPGPPEGPVVISGVTAEKCTLAWKPP 16289

Query: 1746  NVQLTGYRV--RVTPKEKTGPM--KEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTS 1801
              +Q  G  +   +  + +T  +    ++    + S  V+ L+   +Y   + A+      
Sbjct: 16290 -LQDGGSDIINYIVERRETSRLVWTVVDANVQTLSCKVTKLLEGNEYTFRIMAVNKYGVG 16348

Query: 1802  RPAQGVVTTLEN--VSP--PRRARVTDATETTITISWRTKT----ETITGFQVDAVPANG 1853
              P +      +N  V P  P+   VT  T+ ++ + W          I G+ ++     G
Sbjct: 16349 EPLESEPVVAKNPFVVPDAPKAPEVTTVTKDSMIVVWERPASDGGSEILGYVLEKRDKEG 16408

Query: 1854  --QTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDA-STAID------ 1904
                T   + +  ++R   +TGL    DY+  +   N    S P    A   A D      
Sbjct: 16409 IRWTRCHKRLIGELR-LRVTGLIENHDYEFRVSAENAAGLSEPSPPSAYQKACDPIYKPG 16467

Query: 1905  APSNLRFLATTPNSLLVSWQPP----RARITGYIIK 1936
              P+N + +  T +S+ +SW  P       I GYI++
Sbjct: 16468 PPNNPKVIDITRSSVFLSWSKPIYDGGCEIQGYIVE 16503



 Score =  106 bits (265), Expect = 2e-22
 Identities = 287/1431 (20%), Positives = 492/1431 (34%), Gaps = 191/1431 (13%)

Query: 730  EITASSFVVSWVSASDT----VSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRK 785
            +IT  S  ++W    D     ++G+ VE          + +D   T     +PDL+ G++
Sbjct: 7126 DITKDSVHLTWEPPDDDGGSPLTGYVVEKREVSRKTWTKVMDFV-TDLEFTVPDLVQGKE 7184

Query: 786  YIVNVYQISE--DGEQSLILSTSQTTAPDAPPDP--TVDQVDDT--SIVVRWSRPQ---- 835
            Y+  V   ++   GE + +      + P   PDP   V   D T  SI + W  P+    
Sbjct: 7185 YLFKVCARNKCGPGEPAYVDEPVNMSTPATVPDPPENVKWRDRTANSIFLTWDPPKNDGG 7244

Query: 836  APITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQ 895
            + I GY +   P           P     + ++ L+ G  Y   + A+     S P    
Sbjct: 7245 SRIKGYIVERCPRGSDKWVACGEPVAETKMEVTGLEEGKWYAYRVKALNRQGASKPSRPT 7304

Query: 896  QETTGTPRSDTVPSPRDLQFVEVTDVKV-------TIMWTPPESAVTGYRVDVIPVNLPG 948
            +E       +      D++ +    VK          +   PE  +T  + D+I      
Sbjct: 7305 EEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKR 7364

Query: 949  EHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNE 1008
               + +P         +  S   TY  +   V  GR +  +      K   P      + 
Sbjct: 7365 ITIENVPKKSTVTIVDSKRSDTGTYIIEAVNVC-GRATAVVEVNVLDKPGPPAAFDITDV 7423

Query: 1009 TDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTV 1064
            T+ + L+ W PPR    ++IT Y +    T      + +     + +    L P  EY  
Sbjct: 7424 TNESCLLTWNPPRDDGGSKITNYVVERRATDSEVWHKLSSTVKDTNFKATKLIPNKEYIF 7483

Query: 1065 SLVA--IKGNQESPKATGVFTTLQPGSSIPPYNTE---VTETTIVITWTP------APRI 1113
             + A  + G  E  +A+ +    Q     PP   E   +T+  + +TW        +P  
Sbjct: 7484 RVAAENMYGVGEPVQASPITAKYQFDPPGPPTRLEPSDITKDAVTLTWCEPDDDGGSPIT 7543

Query: 1114 GF---KLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTI---QVLRDGQERDAPIV 1167
            G+   +L     +     +    D+ +  V GLT   +Y + +    +   G+   +   
Sbjct: 7544 GYWVERLDPDTDKWVRCNKMPVKDT-TYRVKGLTNKKKYRFRVLAENLAGPGKPSKSTEP 7602

Query: 1168 NKVVTPLSPPTNLHLEANPDTGVLTV--SWERSTTPDITGYRITTTPTNGQQGNSLEEVV 1225
              +  P+ PP         D G  +V  +W   T P+  G     +          +E V
Sbjct: 7603 ILIKDPIDPPWPPGKPTVKDVGKTSVRLNW---TKPEHDGGAKIESYVIEMLKTGTDEWV 7659

Query: 1226 HADQSSCTFDNLSPGL----EYNVSVYTVKDDKESVPI--SDTIIPAVP-----PPTDLR 1274
               +   T  +L PGL    EY+  V  V    ES P   SD ++         PP  L 
Sbjct: 7660 RVAEGVPTTQHLLPGLMEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLE 7719

Query: 1275 FTNIGPDTMRVTWAPPPS---IDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPG 1331
              NI  +T  + W  P       +TN++V    V+ +     +  +  D    +T L  G
Sbjct: 7720 VINITKNTADLKWTVPEKDGGSPITNYIVEKRDVRRK-GWQTVDTTVKDTKCTVTPLTEG 7778

Query: 1332 TEYVVSVS-------SVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPR-- 1382
            + YV  V+       S Y + E + L     T    P  +   D+T     + W  P+  
Sbjct: 7779 SLYVFRVAAENAIGQSDYTEIEDSVLAKDTFTTPGPPYALAVVDVTKRHVDLKWEPPKND 7838

Query: 1383 --ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN----GREE 1436
                I  Y I       +   +  +      +  +T++  GTE    + A N    G   
Sbjct: 7839 GGRPIQRYVIEKKERLGTRWVKAGKTAGPDCNFRVTDVIEGTEVQFQVRAENEAGVGHPS 7898

Query: 1437 SP---LLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQE 1493
             P   L I   ++    P DL V  A    + I+W  P            E  G SP+  
Sbjct: 7899 EPTEILSIEDPTSPPSPPLDLHVTDAGRKHIAIAWKPP------------EKNGGSPIIG 7946

Query: 1494 FTVP----GSKSTATIS-------------GLKPGVDYTITVYAVTGRGDSPASSKPISI 1536
            + V     G++    ++             G+ P  +Y + V AV   G     S+P  I
Sbjct: 7947 YHVEMCPVGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAIG----VSEPSEI 8002

Query: 1537 NYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTE 1596
            +       P      D++ + I V      S    +R    P         +    D+  
Sbjct: 8003 SENVVAKDPDCKPTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLT 8062

Query: 1597 MTIEGLQPTVEYVVSVYA---------QNPSGESQPLVQTAVTNIDRP-KGLAFTDVDVD 1646
            M  + +   +E   SV A         +N  G +   +   V  +  P K +  +D+   
Sbjct: 8063 MKNDHISAHLEVPKSVRADAGIYTITLENKLGSATASINVKVIGLPGPCKDIKASDITKS 8122

Query: 1647 SIKIAWESPQ--GQVSRYRVTYSSPEDGIHELFPAPDGEEDTA-ELQGLRPGSEYTVSVV 1703
            S K+ WE P+  G            E G     P   GE   +  ++ L P  EY   V 
Sbjct: 8123 SCKLTWEPPEFDGGTPILHYVLERREAGRRTYIPVMSGENKLSWTVKDLIPNGEYFFRVK 8182

Query: 1704 ALH-----DDME-SQPLIGTQSTAIP-APTDLKFTQVTPTSLSAQWTPP----NVQLTGY 1752
            A++     + +E   P+I       P  P D++    T  +++  W PP      ++ GY
Sbjct: 8183 AVNKVGGGEYIELKNPVIAQDPKQPPDPPVDVEVHNPTAEAMTITWKPPLYDGGSKIMGY 8242

Query: 1753 RV-RVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTL 1811
             + ++   E+       +L P   +    GL    +Y+  V A      S P++    T 
Sbjct: 8243 IIEKIAKGEERWKRCNEHLVP-ILTYTAKGLEEGKEYQFRVRAENAAGISEPSRATPPT- 8300

Query: 1812 ENVSPPRRARVTDATETTI------------------TISWRTKTETITGFQVD------ 1847
            + V P    +V   T   +                  TI+W      I   ++       
Sbjct: 8301 KAVDPIDAPKVILRTSLEVKRGDEIALDASISGSPYPTITWIKDENVIVPEEIKKRAAPL 8360

Query: 1848 --------------AVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTL-NDNA-R 1891
                           +P   +  I  + K + +      L+P  D+ +Y+  + ND+   
Sbjct: 8361 VRRRKGEVQEEEPFVLPLTQRLSIDNSKKGESQLRVRDSLRP--DHGLYMIKVENDHGIA 8418

Query: 1892 SSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPP----RARITGYIIKYEKPGSPPRE- 1946
             +P  +        P N  F      S+L  W+PP     + I  Y ++ +    P  E 
Sbjct: 8419 KAPCTVSVLDTPGPPINFVFEDIRKTSVLCKWEPPLDDGGSEIINYTLEKKDKTKPDSEW 8478

Query: 1947 VVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQKTPF 1997
            +V        + ++T L  G EY ++ +  +N     P    K  V K PF
Sbjct: 8479 IVVTSTLRHCKYSVTKLIEGKEY-LFRVRAENRFGPGPPCVSKPLVAKDPF 8528



 Score =  106 bits (264), Expect = 3e-22
 Identities = 321/1571 (20%), Positives = 563/1571 (35%), Gaps = 259/1571 (16%)

Query: 590   YGRGIGEWHCQPLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQP---SHISKYILRWR 646
             YG G+     +P++       P  V + +     N+  I+W  P+    S I+ Y++  +
Sbjct: 18906 YGIGLPAETTEPVKVSEPPLPPGRVTLVDVTR--NTATIKWEKPESDGGSKITGYVVEMQ 18963

Query: 647   PKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPV 706
              K S  +W   T    L + TI GL  G  Y  ++ ++ + G  +  +          PV
Sbjct: 18964 TKGSE-KWSTCTQVKTLEA-TISGLTAGEEYVFRVAAVNEKGRSDPRQL-------GVPV 19014

Query: 707   TSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYL 766
              +  +  E  P   L   + +V         V +         +R + +  +E      +
Sbjct: 19015 IARDI--EIKPSVELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVN-V 19071

Query: 767   DLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDP---TVDQVD 823
                 T TS++I +     K  V  Y++        I         D P  P    +D+V 
Sbjct: 19072 SSSKTVTSLSIKE---ASKEDVGTYELCVSNSAGSITVPITIIVLDRPGPPGPIRIDEVS 19128

Query: 824   DTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNIT 879
               SI + W+ P+      I+ Y +    +   +   ++      S+ +  L  G +Y   
Sbjct: 19129 CDSITISWNPPEYDGGCQISNYIVEKKETTSTTWHIVSQAVARTSIKIVRLTTGSEYQFR 19188

Query: 880   I-----YAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE--- 931
             +     Y      ES+ VV +      P S   P P   + V  T   + + W  P    
Sbjct: 19189 VCAENRYGKSSYSESSAVVAEY-----PFSPPGP-PGTPKVVHATKSTMLVTWQVPVNDG 19242

Query: 932   -SAVTGYRVDVIP-VNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFA---VSHGRES 986
              S V GY ++     ++      ++ I+ +T  +V+GL  G+ Y ++V+A      G+ S
Sbjct: 19243 GSRVIGYHLEYKERSSILWSKANKILIA-DTQMKVSGLDEGLMYEYRVYAENIAGIGKCS 19301

Query: 987   K---PLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPR----AQITGY-----RLTVG-- 1032
             K   P+ A+     D P   +  N T  +V ++W+ P     A+ITGY      L  G  
Sbjct: 19302 KSCEPVPARDPC--DPPGQPEVTNITRKSVSLKWSKPHYDGGAKITGYIVERRELPDGRW 19359

Query: 1033  --------------LTRRGQPRQY-------NVGPSVSKYPLRNLQPASEYTVSLVAIKG 1071
                           +T   + ++Y       N   SVS+         SE T  ++ +K 
Sbjct: 19360 LKCNYTNIQETYFEVTELTEDQRYEFRVFARNAADSVSE--------PSESTGPII-VKD 19410

Query: 1072  NQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGF-KLGVRPSQGGEAPRE 1130
             + E P+   V   ++    I     EV +    I   P P I + K G+   +       
Sbjct: 19411 DVEPPR---VMMDVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEII 19467

Query: 1131  VTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGV 1190
              T +   + V          Y + +      R   +  KV+    PP    LE N  T  
Sbjct: 19468 STDNHTLLTVKDCIRRDTGQYVLTLKNVAGTRSVAVNCKVLDKPGPPAG-PLEINGLTAE 19526

Query: 1191  -LTVSWERSTTP---DITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEY--- 1243
               ++SW R       DI  Y +    T+       E  +    +SC    L  G EY   
Sbjct: 19527 KCSLSWGRPQEDGGADIDYYIVEKRETSHLAWTICEGELQ--MTSCKVTKLLKGNEYIFR 19584

Query: 1244  --NVSVYTVKDDKESVPISDTIIPAVP-PPTDLRFTNIGPDTMRVTWAPPPS---IDLTN 1297
                V+ Y V +  ESV I       VP PPT L  T++  ++M + W+ P S    +++ 
Sbjct: 19585 VTGVNKYGVGEPLESVAIKALDPFTVPSPPTSLEITSVTKESMTLCWSRPESDGGSEISG 19644

Query: 1298  FLVRYSPVKNEEDVAELSISP-SDNAVVLTNLLPGTEYVVSV-----SSVYEQHESTPL- 1350
             +++     KN      ++  P  D  V  T L  G EY   V     + +    E++PL 
Sbjct: 19645 YIIERRE-KNSLRWVRVNKKPVYDLRVKSTGLREGCEYEYRVYAENAAGLSLPSETSPLI 19703

Query: 1351  RGRQKTGLDS-PTGIDFSDITANSFTVHWIAP----RATITGYRIRHHPEHFSGRPREDR 1405
             R      L S P+     D    + T+ W+ P     A ITGY + +  +       +  
Sbjct: 19704 RAEDPVFLPSPPSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEY--KKSDDTDWKTS 19761

Query: 1406  VPHSRNS-ITLTNLTPGTEYVVSIVALN-----------------GREESPLLIGQQSTV 1447
             +   R +  T++ LT G EYV  + ++N                  REE PL        
Sbjct: 19762 IQSLRGTEYTISGLTTGAEYVFRVKSVNKVGASDPSDSSDPQIAKEREEEPLF----DID 19817

Query: 1448  SDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFT-VPGSKSTATI- 1505
             S++ + L V A    ++ + +    V      + + +   +   + +     S+++ TI 
Sbjct: 19818 SEMRKTLIVKAGASFTMTVPFRGRPVP----NVLWSKPDTDLRTRAYVDTTDSRTSLTIE 19873

Query: 1506  -SGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKW-L 1563
              +       YT+T+  V       A+S  + +        P+ + V DV   S  + W +
Sbjct: 19874 NANRNDSGKYTLTIQNVLS-----AASLTLVVKVLDTPGPPTNITVQDVTKESAVLSWDV 19928

Query: 1564  PSS---SPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE 1620
             P +   +PV  Y +     +        T   ++    +  LQ    Y   V  +N  G 
Sbjct: 19929 PENDGGAPVKNYHIEKREASKKAWVSV-TNNCNRLSYKVTNLQEGAIYYFRVSGENEFGV 19987

Query: 1621  SQPLVQTAVTNIDR----PKGLAFTDVDVDSIKIAWESPQGQVSRYRVTY--SSPEDGIH 1674
               P        I      P+ L  T +  DS+ + W  P+       V Y   + E G  
Sbjct: 19988 GIPAETKEGVKITEKPSPPEKLGVTSISKDSVSLTWLKPEHDGGSRIVHYVVEALEKGQK 20047

Query: 1675  ELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVT 1734
                     +     + GLR  SEY   V A     E+Q         +  P +L    + 
Sbjct: 20048 NWVKCAVAKSTHHVVSGLRENSEYFFRVFA-----ENQ-------AGLSDPREL----LL 20091

Query: 1735  PTSLSAQWTPPNVQL-----------TGYRVRVTPKEKTGPMKEINLAPD---------- 1773
             P  +  Q  PP + +            G  ++V       P+ ++ L+ D          
Sbjct: 20092 PVLIKEQLEPPEIDMKNFPSHTVYVRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRF 20151

Query: 1774  SSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGV------VTTLENVSPPR-RARVTDAT 1826
             ++ +    L +  K  V+  A +  +T+  + G       +  L+   PP     ++D T
Sbjct: 20152 NTEITAENLTINLKESVTADAGRYEITAANSSGTTKAFINIVVLDRPGPPTGPVVISDIT 20211

Query: 1827  ETTITISWR---------------TKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTIT 1871
             E ++T+ W                 K ET T     AV       + RT+        + 
Sbjct: 20212 EESVTLKWEPPKYDGGSQVTNYILLKRETST-----AVWTEVSATVARTM------MKVM 20260

Query: 1872  GLQPGTDYKIYL-----YTLNDNARSSPVVIDASTAIDAPSNLRFLA-TTPNSLLVSWQP 1925
              L  G +Y+  +     + ++D+  S+ V +        P +  ++   T  S+ V W  
Sbjct: 20261 KLTTGEEYQFRIKAENRFGISDHIDSACVTVKLPYTTPGPPSTPWVTNVTRESITVGWHE 20320

Query: 1926  P----RARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIAL----- 1976
             P     + + GY ++ +   S   +   +     T   +T +  G  Y   V A      
Sbjct: 20321 PVSNGGSAVVGYHLEMKDRNSILWQKANKLVIRTTHFKVTTISAGLIYEFRVYAENAAGV 20380

Query: 1977  -KNNQKSEPLI 1986
              K +  SEP++
Sbjct: 20381 GKPSHPSEPVL 20391



 Score =  105 bits (263), Expect = 4e-22
 Identities = 305/1451 (21%), Positives = 530/1451 (36%), Gaps = 208/1451 (14%)

Query: 688   GHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWV----SA 743
             G Q + R      S S PV    +     P  P+      VT +T+    ++W       
Sbjct: 17321 GGQYILRASNVAGSKSFPVNVKVLDRPGPPEGPV-----QVTGVTSEKCSLTWSPPLQDG 17375

Query: 744   SDTVSGFRVEYELSEEGDEPQYLDLPS--TATSVNIPDLLPGRKYI-----VNVYQISED 796
                +S + VE     E     +  + S     S+ +  LL G +Y+     VN Y + E 
Sbjct: 17376 GSDISHYVVE---KRETSRLAWTVVASEVVTNSLKVTKLLEGNEYVFRIMAVNKYGVGEP 17432

Query: 797   GEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ----APITGYRIVYSPSVEG- 851
              E + +L  +    P  P    V  +   S+ V W+RP     + I GY IV      G 
Sbjct: 17433 LESAPVLMKNPFVLPGPPKSLEVTNIAKDSMTVCWNRPDSDGGSEIIGY-IVEKRDRSGI 17491

Query: 852   ---SSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVP 908
                   +  + +    VT        ++ ++        E +P  +  +    P     P
Sbjct: 17492 RWIKCNKRRITDLRLRVTGLTEDHEYEFRVSAENAAGVGEPSPATVYYKAC-DPVFKPGP 17550

Query: 909   SPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPGEHGQRLPIS---RNTF 961
              P +   V+ T   +T+ W  P     S + GY V++   +   E  Q +      R T 
Sbjct: 17551 -PTNAHIVDTTKNSITLAWGKPIYDGGSEILGYVVEICKAD--EEEWQIVTPQTGLRVTR 17607

Query: 962   AEVTGLSPGVTYYFKVFAVSH----GRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRW 1017
              E++ L+    Y  +V A++        S P T +   KL+AP  L   +E    ++VR 
Sbjct: 17608 FEISKLTEHQEYKIRVCALNKVGLGEATSVPGTVKPEDKLEAP-ELDLDSELRKGIVVR- 17665

Query: 1018  TPPRAQITGYRLTVGLTRRGQPR----------------QYNVGPSVSKYPLRNL--QPA 1059
                     G    + +  +G+P                 Q   G + ++  + N     A
Sbjct: 17666 -------AGGSARIHIPFKGRPTPEITWSREEGEFTDKVQIEKGVNYTQLSIDNCDRNDA 17718

Query: 1060  SEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYN---TEVTETTIVITWTPAPRI--G 1114
              +Y + L    G++ +     V  T  PG   PP N    EV + +  + W P P I  G
Sbjct: 17719 GKYILKLENSSGSKSAFVTVKVLDT--PG---PPQNLAVKEVRKDSAFLVWEP-PIIDGG 17772

Query: 1115  FKLGVRPSQGGEAPREVTSD------SGSIVVSGLTPGVEYVYTIQVLRD---GQERDAP 1165
              K+        E+ R+  ++        S  V  LT G  Y + +    +   G   +  
Sbjct: 17773 AKVKNYVIDKRESTRKAYANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFGVGVPVETV 17832

Query: 1166  IVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPD---ITGYRITTTPTNGQQGNSLE 1222
                K   P SPP  + L     T   ++ WE+        + GY +   P   ++ + + 
Sbjct: 17833 DAVKAAEPPSPPGKVTLTDVSQTSA-SLMWEKPEHDGGSRVLGYVVEMQPKGTEKWSIVA 17891

Query: 1223  EVVHADQSSCTFDNLSPGLEY--NVSVYTVKDDKE----SVPI---SDTIIPAVPPPTDL 1273
             E   +   +     LS G EY   V  Y  K   +     VP+     TI P++  P + 
Sbjct: 17892 E---SKVCNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKLPFNT 17948

Query: 1274  RFTNIGPD---TMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLP 1330
                  G D    + V   P P+I   +++    P+K       +++  +  + VL ++  
Sbjct: 17949 YSIQAGEDLKIEIPVIGRPRPNI---SWVKDGEPLK---QTTRVNVEETATSTVL-HIKE 18001

Query: 1331  GTE------YVVSVSSVYEQHESTPLRGRQKTGLDSPTG-IDFSDITANSFTVHWIAPRA 1383
             G +       V + +S     E+  +   +K G   P G + F +++A+   + W  P  
Sbjct: 18002 GNKDDFGKYTVTATNSAGTATENLSVIVLEKPG--PPVGPVRFDEVSADFVVISWEPPAY 18059

Query: 1384  T----ITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPL 1439
             T    I+ Y +    +  +          +R +I +T L  GTEY   I A N   +S  
Sbjct: 18060 TGGCQISNYIVEKR-DTTTTTWHMVSATVARTTIKITKLKTGTEYQFRIFAENRYGKSAP 18118

Query: 1440  LIGQQSTVS------DVPRDLEVVAATPTSLLISWDAP----AVTVRYYRITYGETGGNS 1489
             L  +   V         P    V + +   +L+ W  P       +  Y +   E     
Sbjct: 18119 LDSKAVIVQYPFKEPGPPGTPFVTSISKDQMLVQWHEPVNDGGTKIIGYHLEQKEKNSIL 18178

Query: 1490  PVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQ 1549
              V+    P   +    +GL  G++Y   V A    G    S        R   D P + +
Sbjct: 18179 WVKLNKTPIQDTKFKTTGLDEGLEYEFKVSAENIVGIGKPSKVSECFVARDPCDPPGRPE 18238

Query: 1550  VTDVQDNSISVKW----LPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPT 1605
                +  N++++KW        S +TGY V           K       +TE T+ GL   
Sbjct: 18239 AIVITRNNVTLKWKKPAYDGGSKITGYIVEKKDLPDGRWMKASFTNVLETEFTVSGLVED 18298

Query: 1606  VEYVVSVYAQNPSGE-SQPLVQT-AVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYR 1663
               Y   V A+N +G  S+P   + A+T  D        ++D  +  +  +     V    
Sbjct: 18299 QRYEFRVIARNAAGNFSEPSDSSGAITARD--------EIDAPNASLDPKYKDVIVVHAG 18350

Query: 1664  VTYSSPED----GIHELFPAPDGE--EDTAELQGLRPGSEYTVSVV--ALHDD-----ME 1710
              T+    D     I ++  + DG+  E+TA    ++   + T  VV   +  D     ++
Sbjct: 18351 ETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQYILK 18410

Query: 1711  SQPLIGTQSTAI-------PAPTD--LKFTQVTPTSLSAQWTPPNVQLTGYRVR--VTPK 1759
                + GT+S  I       P P +  LK T VT       W PP +Q  G  +   +  K
Sbjct: 18411 LSNVGGTKSIPITVKVLDRPGPPEGPLKVTGVTAEKCYLAWNPP-LQDGGANISHYIIEK 18469

Query: 1760  EKTGPMK--EINLAPDSSSVVVSGLMVATKY-----EVSVYALKDTLTSRPAQGVVTTLE 1812
              +T  +   +++    + +  V+ L+   +Y      V+ Y + + L S P        +
Sbjct: 18470 RETSRLSWTQVSTEVQALNYKVTKLLPGNEYIFRVMAVNKYGIGEPLESGPVT-ACNPYK 18528

Query: 1813  NVSPPRRARVTDATETTITISWRTKTE----TITGFQVDAVPANG--QTPIQRTIKPDVR 1866
                PP    V+  T+ ++ ++W    +     I G+ ++     G   T   +    D+R
Sbjct: 18529 PPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDKEGVRWTKCNKKTLTDLR 18588

Query: 1867  SYTITGLQPGTDYKIYLYTLNDNARSSPV-------VIDASTAIDAPSNLRFLATTPNSL 1919
                +TGL  G  Y+  +   N      P          DA      PSN +   T+ +S+
Sbjct: 18589 -LRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRACDALYPPGPPSNPKVTDTSRSSV 18647

Query: 1920  LVSWQPP----RARITGYIIKYEKPGSPPREVVPRPRPGV--TEATITGLEPGTEYTIYV 1973
              ++W  P     A + GY+++  K  +        P  G+   + T+T L+  TEY   +
Sbjct: 18648 SLAWSKPIYDGGAPVKGYVVEV-KEAAADEWTTCTPPTGLQGKQFTVTKLKENTEYNFRI 18706

Query: 1974  IALKNNQKSEP 1984
              A+ +    EP
Sbjct: 18707 CAINSEGVGEP 18717



 Score =  103 bits (258), Expect = 2e-21
 Identities = 284/1417 (20%), Positives = 486/1417 (34%), Gaps = 169/1417 (11%)

Query: 606   PSSSGPVEVFITETPSQPNSHPIQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGH 662
             P   GPVE+    +        + W  P     S I  YIL  R  + +  W   +    
Sbjct: 14101 PGPPGPVEI----SNVSAEKATLTWTPPLEDGGSPIKSYILEKRETSRL-LWTVVSEDIQ 14155

Query: 663   LNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLV 722
                +    L  G  Y  ++ ++  YG  E             PV S  V        P  
Sbjct: 14156 SCRHVATKLIQGNEYIFRVSAVNHYGKGE-------------PVQSEPVKMVDRFGPPGP 14202

Query: 723   ATSESVTEITASSFVVSWVSASDT----VSGFRVEYELSEEGDEPQYLDLPSTATSVNIP 778
                  V+ +T ++  VSW    D     ++G+ VE    +     + +  P +     + 
Sbjct: 14203 PEKPEVSNVTKNTATVSWKRPVDDGGSEITGYHVERREKKSLRWVRAIKTPVSDLRCKVT 14262

Query: 779   DLLPGRKYIVNVYQISEDG------EQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWS 832
              L  G  Y   V   +  G          +L       P  P +P V      S  + W 
Sbjct: 14263 GLQEGSTYEFRVSAENRAGIGPPSEASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLAWG 14322

Query: 833   RPQ----APITGYRIVYSPSVEGSSTELNLPETANSVT---LSDLQPGVQYNITIYAVEE 885
             +P       ITGY +V    V   +   +   TA  +T   + DLQ   +YN  I A+ +
Sbjct: 14323 KPHYDGGLEITGY-VVEHQKVGDEAWIKDTTGTALRITQFVVPDLQTKEKYNFRISAIND 14381

Query: 886   NQESTPVVIQQ-ETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPV 944
                  P VI   E      +       +L+   V    ++I    P        V     
Sbjct: 14382 AGVGEPAVIPDVEIVEREMAPDFELDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKD 14441

Query: 945   NLPGEHGQRLPISRNTFAEVTGLSPGVTYYF--KVFAVSHGRESKPLTAQQTTKLDAP-- 1000
             N+  ++   +    NT +    + P    Y   K          K         LD P  
Sbjct: 14442 NINLKNRANI---ENTESFTLLIIPECNRYDTGKFVMTIENPAGKKSGFVNVRVLDTPGP 14498

Query: 1001  -TNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSK-----YPLR 1054
               NL+  + T  +V + W  P     G R+T  +  + +  + +   + +K     Y + 
Sbjct: 14499 VLNLRPTDITKDSVTLHWDLPLID-GGSRITNYIVEKREATRKSYSTATTKCHKCTYKVT 14557

Query: 1055  NLQPASEYTVSLVAIK--GNQESPKATGVFTTLQPGSSIPPYNT-EVTETTIVITWTPAP 1111
              L    EY   ++A    G  E  + T      +  S     N  ++T++T+ + W P P
Sbjct: 14558 GLSEGCEYFFRVMAENEYGIGEPTETTEPVKASEAPSPPDSLNIMDITKSTVSLAW-PKP 14616

Query: 1112  R-------IGFKLGVRPSQGGEAPREVTSDSG-SIVVSGLTPGVEYVYTIQVL----RDG 1159
             +        G+ +  +  +G +    +T+  G   VV  LT G EY + +  +    R  
Sbjct: 14617 KHDGGSKITGYVIEAQ-RKGSDQWTHITTVKGLECVVRNLTEGEEYTFQVMAVNSAGRSA 14675

Query: 1160  QERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWE--RSTTPDITGYRITTTPTNGQQ 1217
                  P++ K  T L     L L       V+  + +  +   P +   + T T   G Q
Sbjct: 14676 PRESRPVIVKEQTMLP---ELDLRGIYQKLVIAKAGDNIKVEIPVLGRPKPTVTWKKGDQ 14732

Query: 1218  G-NSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAV-----PPPT 1271
                  + V     ++ T  N++  +  +   Y +        + D I   V     PP  
Sbjct: 14733 ILKQTQRVNFETTATSTILNINECVRSDSGPYPLTARNIVGEVGDVITIQVHDIPGPPTG 14792

Query: 1272  DLRFTNIGPDTMRVTWAPPPS---IDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNL 1328
              ++F  +  D +  +W PP +   + ++N++V      +   V EL+ +        T L
Sbjct: 14793 PIKFDEVSSDFVTFSWDPPENDGGVPISNYVVEMRQTDSTTWV-ELATTVIRTTYKATRL 14851

Query: 1329  LPGTEYVVSVSS-----VYEQHESTPLRGRQKTGLDSPTGI-DFSDITANSFTVHWIAP- 1381
               G EY   V +     V     S  +       +  P G    + +T +S T+ W  P 
Sbjct: 14852 TTGLEYQFRVKAQNRYGVGPGITSACIVANYPFKVPGPPGTPQVTAVTKDSMTISWHEPL 14911

Query: 1382  ---RATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN------ 1432
                 + I GY +     +        +     N    + LT G  Y   ++A N      
Sbjct: 14912 SDGGSPILGYHVERKERNGILWQTVSKALVPGNIFKSSGLTDGIAYEFRVIAENMAGKSK 14971

Query: 1433  -GREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPV 1491
               +   P+L          P  L +   T T   + W  P  T  +   +Y     + P 
Sbjct: 14972 PSKPSEPMLALDPIDPPGKPVPLNITRHTVT---LKWAKPEYTGGFKITSYIVEKRDLPN 15028

Query: 1492  QEFTVPG----SKSTATISGLKPGVDYTITVYAVTGRGD-SPASSKPISINYRTEIDKPS 1546
               +         ++  T+SGL     Y   V A    G  SP S    +I  R +++ P 
Sbjct: 15029 GRWLKANFSNILENEFTVSGLTEDAAYEFRVIAKNAAGAISPPSEPSDAITCRDDVEAPK 15088

Query: 1547  QMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTK------TKTAGPDQTEMTIE 1600
                    +D  I             +R+       P PT        +  G  + E+ I 
Sbjct: 15089 IKVDVKFKDTVI-------LKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIA 15141

Query: 1601  GLQPTV---------EYVVSVYAQNPSGESQPLVQTAVTNIDRP----KGLAFTDVDVDS 1647
                  +             ++ A NP G ++ +    V  +DRP      LA T+V  + 
Sbjct: 15142 DFSTNLVNKDSTRRDSGAYTLTATNPGGFAKHIFNVKV--LDRPGPPEGPLAVTEVTSEK 15199

Query: 1648  IKIAWESP---QGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVA 1704
               ++W  P    G    + +        +     A + +    ++  L  G+EY   V+A
Sbjct: 15200 CVLSWFPPLDDGGAKIDHYIVQKRETSRLAWTNVASEVQVTKLKVTKLLKGNEYIFRVMA 15259

Query: 1705  LH-----DDMESQPLIGTQSTAIP-APTDLKFTQVTPTSLSAQWTPPN----VQLTGYRV 1754
             ++     + +ES+P++       P  P + + T +T  S+   W  P+     ++  Y V
Sbjct: 15260 VNKYGVGEPLESEPVLAVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEIINYIV 15319

Query: 1755  RVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYA-----LKDTLTSRPAQGVVT 1809
                 K     +K            VSGL    +YE  + A     +     + P      
Sbjct: 15320 ERRDKAGQRWIKCNKKTLTDLRYKVSGLTEGHEYEFRIMAENAAGISAPSPTSPFYKACD 15379

Query: 1810  TLENVSPPRRARVTDATETTITISWRTKT----ETITGFQVD-AVPANGQTPIQRTIKP- 1863
             T+    PP   RV D + ++I+I+W          ITG+ V+ A+P   +  I   + P 
Sbjct: 15380 TVFKPGPPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQI---VTPP 15436

Query: 1864  ---DVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVI 1897
                   SYTITGL    +YKI +Y +N      P ++
Sbjct: 15437 AGLKATSYTITGLTENQEYKIRIYAMNSEGLGEPALV 15473



 Score =  101 bits (252), Expect = 7e-21
 Identities = 270/1291 (20%), Positives = 463/1291 (35%), Gaps = 206/1291 (15%)

Query: 866   TLSDLQPGVQYNITIYAVEENQEST-PVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVT 924
             T++ L  G +Y   + A  EN+  T P    +      + D    P   +  +V+  ++T
Sbjct: 11984 TVTRLIEGNEYIFRVRA--ENKIGTGPPTESKPVIAKTKYDKPGRPDPPEVTKVSKEEMT 12041

Query: 925   IMWTPPE----SAVTGYRVDVIPVNLPGEHGQR-LPISRNTFAE----VTGLSPGVTYYF 975
             ++W PPE     ++TGY ++        +H  R +P++++   E    V  L P   Y F
Sbjct: 12042 VVWNPPEYDGGKSITGYFLEK-----KEKHSTRWVPVNKSAIPERRMKVQNLLPDHEYQF 12096

Query: 976   KVFAVSH------GRESKPLTAQQTTKLDAP-TNLQFVNETDSTVLVRWTPP----RAQI 1024
             +V A +          S+P+ A+   +   P TN + V+ T  ++ + W  P     A I
Sbjct: 12097 RVKAENEIGIGEPSLPSRPVVAKDPIEPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAPI 12156

Query: 1025  TGY------RLTVGLTRRGQPRQYNVGPSVSK-YPLRNLQPASEYTVSL-----VAIKGN 1072
              GY      ++       G  R       V K + + +L    EY   +     V I   
Sbjct: 12157 IGYVVEMRPKIADASPDEGWKRCNAAAQLVRKEFTVTSLDENQEYEFRVCAQNQVGIGRP 12216

Query: 1073  QESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWT-------------PAPRIGFKLGV 1119
              E  +A      L+P    P  + + +   +VI                PAP++ ++   
Sbjct: 12217 AELKEAIKPKEILEP----PEIDLDASMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVG 12272

Query: 1120  RPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTN 1179
               +   +   ++      +V+   T      Y++ ++    E+   +  +V+    P ++
Sbjct: 12273 IDNVVRKGQVDLVDTMAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFVNVRVLDTPGPVSD 12332

Query: 1180  LHLEANPDTGVLTVSW---ERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDN 1236
             L +     T    VSW   E      +T Y +     + +  +++   V   ++S    N
Sbjct: 12333 LKVSDVTKTSC-HVSWAPPENDGGSQVTHYIVEKREADRKTWSTVTPEVK--KTSFHVTN 12389

Query: 1237  LSPGLEYNVSVYTVKDDKESVP--ISDTIIPAVP-----PPTDLRFTNIGPDTMRVTWAP 1289
             L PG EY   V  V +    VP  +   ++ + P     PP  L  T +  ++  + W P
Sbjct: 12390 LVPGNEYYFRVTAVNEYGPGVPTDVPKPVLASDPLSEPDPPRKLEVTEMTKNSATLAWLP 12449

Query: 1290  P---PSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHE 1346
             P       +  ++  Y   +   D         D ++V+T L  G +Y   V++      
Sbjct: 12450 PLRDGGAKIDGYITSYREEEQPADRWTEYSVVKDLSLVVTGLKEGKKYKFRVAARNAVGV 12509

Query: 1347  STPLRGR----QKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPR 1402
             S P         K  L  P  +    IT  +             G ++R    H  G+P 
Sbjct: 12510 SLPREAEGVYEAKEQLLPPKILMPEQITIKA-------------GKKLRIEA-HVYGKPH 12555

Query: 1403  --------EDRV----------PHSRNSITLTNLTPGTEYVVSIVALNGR----EESPLL 1440
                     ED V            S + + + ++T       S+ A N      ++  ++
Sbjct: 12556 PTCKWKKGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVV 12615

Query: 1441  IGQQSTVSDVPRDLEVVAATPTSLLISWDAP----AVTVRYYRITYGETGGNSPVQEFTV 1496
             +         P D+  + A   SL  SW  P       +  Y +   +      V     
Sbjct: 12616 VMDAPGPPQPPFDISDIDADACSL--SWHIPLEDGGSNITNYIVEKCDVSRGDWVTALAS 12673

Query: 1497  PGSKSTATISGLKPGVDYTITVYAVTGRGDS-PASSKPISINYRTEI-DKPSQMQVTDVQ 1554
               +K++  +  L PG +Y   V A    G S P +S  +   +   +  +P   +VT V 
Sbjct: 12674 V-TKTSCRVGKLIPGQEYIFRVRAENRFGISEPLTSPKMVAQFPFGVPSEPKNARVTKVN 12732

Query: 1555  DNSISVKW-LPSS---SPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVV 1610
              + I V W  P S   SP+ GY +    +N     K        TE    GL   +EY  
Sbjct: 12733 KDCIFVAWDRPDSDGGSPIIGYLIERKERNSLLWVKANDTLVRSTEYPCAGLVEGLEYSF 12792

Query: 1611  SVYAQNPSGESQPLVQTAVTN----IDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTY 1666
              +YA N +G S P   T        +D P      DV   ++ + W  P+       + Y
Sbjct: 12793 RIYALNKAGSSPPSKPTEYVTARMPVDPPGKPEVIDVTKSTVSLIWARPKHDGGSKIIGY 12852

Query: 1667  -----SSPEDGIHELFPAPDG---EEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQ 1718
                    P D       AP     EE TA   GL   ++Y    +A      S P     
Sbjct: 12853 FVEACKLPGDKWVRCNTAPHQIPQEEYTAT--GLEEKAQYQFRAIARTAVNISPP----- 12905

Query: 1719  STAIPAPTDLKFTQVTPTSLSAQWTPPNVQLT-GYRVRVTPKEKTG----------PMKE 1767
                   P+D       P ++ A+  PP + L+   +  +T K  T           PM  
Sbjct: 12906 ----SEPSD-------PVTILAENVPPRIDLSVAMKSLLTVKAGTNVCLDATVFGKPMPT 12954

Query: 1768  INLAPDSSSVV-VSGLMVATKYEVSVYAL-----KD----TLTSRPAQGV------VTTL 1811
             ++   D + +    G+ +A +  +    L     KD    T+T+  + G       +  L
Sbjct: 12955 VSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTITAENSSGSKSATIKLKVL 13014

Query: 1812  ENVSPPRRARVTDATETTITISWRTKTET----ITGFQVDAVPANGQTPIQRTIKPDVRS 1867
             +   PP   ++         +SW    E     IT + VD    +     Q +    + S
Sbjct: 13015 DKPGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYIVDKRETSRPNWAQVSATVPITS 13074

Query: 1868  YTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTA---IDAPSNLR---FLATTPNSLLV 1921
              ++  L  G +Y+  +   N      PV  + + A    D P           T + + V
Sbjct: 13075 CSVEKLIEGHEYQFRICAENKYGVGDPVFTEPAIAKNPYDPPGRCDPPVISNITKDHMTV 13134

Query: 1922  SWQPPR----ARITGYIIKYEKPGSPPREVVPRPRPGVTEATI--TGLEPGTEYTIYVIA 1975
             SW+PP     + ITGY++  EK  +         R  + E T+  TGL+ GTEY   V A
Sbjct: 13135 SWKPPADDGGSPITGYLL--EKRETQAVNWTKVNRKPIIERTLKATGLQEGTEYEFRVTA 13192

Query: 1976  LKNNQKSEPLIGRKKTVQKTPFVTHPGYDTG 2006
             +    K+ P  G+     K  +   P Y  G
Sbjct: 13193 I---NKAGP--GKPSDASKAAYARDPQYPPG 13218



 Score =  101 bits (252), Expect = 7e-21
 Identities = 308/1501 (20%), Positives = 533/1501 (35%), Gaps = 204/1501 (13%)

Query: 624   NSHPIQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNS--YTIKGLKPGVVYE 678
             NS  + W  P+    S I +YIL  R K S  RW +      ++   + + GL  G  YE
Sbjct: 21794 NSITLTWARPESDGGSEIQQYILERREKKST-RWVKVISKRPISETRFKVTGLTEGNEYE 21852

Query: 679   GQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVV 738
               +++    G    +           PV          P  P V     VT+ + ++  +
Sbjct: 21853 FHVMAENAAGVGPASGIS-RLIKCREPVNP--------PGPPTVV---KVTDTSKTTVSL 21900

Query: 739   SW----VSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQIS 794
              W          + G+ +E   ++ GD  +        T   + DL  G +Y   V  I+
Sbjct: 21901 EWSKPVFDGGMEIIGYIIEMCKADLGDWHKVNAEACVKTRYTVTDLQAGEEYKFRVSAIN 21960

Query: 795   EDGEQSLILSTSQTTAPD--APPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGS 852
               G+      T    A D    P+  +D     + VVR          Y+   +P+   S
Sbjct: 21961 GAGKGDSCEVTGTIKAVDRLTAPELDIDANFKQTHVVRAGASIRLFIAYQGRPTPTAVWS 22020

Query: 853   STELNLPETANSVTLSDLQPGVQYNIT-------IYAVEENQESTPVVIQQETTGTPRSD 905
               + NL   A+  T          N            VE N  S  +    +   TP   
Sbjct: 22021 KPDSNLSLRADIHTTDSFSTLTVENCNRNDAGKYTLTVENNSGSKSITFTVKVLDTPGP- 22079

Query: 906   TVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPGEHGQRLPISRNTF 961
                 P  + F +VT    T+MW  P     + +  Y V+    +           +R  F
Sbjct: 22080 ----PGPITFKDVTRGSATLMWDAPLLDGGARIHHYVVEKREASRRSWQVISEKCTRQIF 22135

Query: 962   AEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQ----TTKLDAPTNLQFVNETDSTVLVRW 1017
              +V  L+ GV YYF+V AV+     +P    +    T +   P  L  V+ + S+ ++ W
Sbjct: 22136 -KVNDLAEGVPYYFRVSAVNEYGVGEPYEMPEPIVATEQPAPPRRLDVVDTSKSSAVLAW 22194

Query: 1018  TPP----RAQITGYRLTVGLTRRGQPRQYNVGPSVS-KYPLRNLQPASEY---------- 1062
               P     ++ITGY L   + ++G       G +    + +  L   +EY          
Sbjct: 22195 LKPDHDGGSRITGYLLE--MRQKGSDFWVEAGHTKQLTFTVERLVEKTEYEFRVKAKNDA 22252

Query: 1063  -------TVSLVAIKGNQESPKA--TGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRI 1113
                      S V IK  Q  P A  TG+   L    +  P+  +V      I+  PAP++
Sbjct: 22253 GYSEPREAFSSVIIKEPQIEPTADLTGITNQLITCKAGSPFTIDVP-----ISGRPAPKV 22307

Query: 1114  GFKL-GVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVT 1172
              +KL  +R  +        T D  ++ V     G    Y + +      +   +   V+ 
Sbjct: 22308 TWKLEEMRLKETDRVSITTTKDRTTLTVKDSMRGDSGRYFLTLENTAGVKTFSVTVVVIG 22367

Query: 1173  PLSPPTNLHLEANPDTGVLTVSW---ERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQ 1229
                P T     ++       +SW   +     +IT Y +    +       +   V   Q
Sbjct: 22368 RPGPVTGPIEVSSVSAESCVLSWGEPKDGGGTEITNYIVEKRESGTTAWQLVNSSVKRTQ 22427

Query: 1230  SSCTFDNLSPGLEYNVSV-----YTVKDDKESVPISDTIIPAVPP--PTDLRFTNIGPDT 1282
                T  +L+  +EY+  V     + V    ES PI     P VPP  PT     ++  + 
Sbjct: 22428 IKVT--HLTKYMEYSFRVSSENRFGVSKPLESAPII-AEHPFVPPSAPTRPEVYHVSANA 22484

Query: 1283  MRVTWAPPPSIDLTNFLVRYSPVKNEED----VAELSISPSDNAVVLTNLLPGTE----- 1333
             M + W  P   D  + ++ Y   K E +    V E  +   +    +T L+ G E     
Sbjct: 22485 MSIRWEEPYH-DGGSKIIGYWVEKKERNTILWVKENKVPCLECNYKVTGLVEGLEYQFRT 22543

Query: 1334  YVVSVSSVYEQHE-STPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPR----ATITGY 1388
             Y ++ + V +  E S P+  +    +D+P   + +D+T ++ ++ W AP     + + GY
Sbjct: 22544 YALNAAGVSKASEASRPIMAQNP--VDAPGRPEVTDVTRSTVSLIWSAPAYDGGSKVVGY 22601

Query: 1389  RIRHHPEHFSGRPREDRVPH---SRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQS 1445
              I   P    G  R  +  +   S N  T+T L+ G  Y   ++A N      +  G +S
Sbjct: 22602 IIERKPVSEVGDGRWLKCNYTIVSDNFFTVTALSEGDTYEFRVLAKNA--AGVISKGSES 22659

Query: 1446  TVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATI 1505
             T     RD            +  D   +      +     GG    +     G K     
Sbjct: 22660 TGPVTCRDEYAPPKAELDARLHGDLVTIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLC 22719

Query: 1506  SGLKPGVDYT----ITVYAVTGRGDS---------PASSKPISINYRTEIDKP---SQMQ 1549
                K  + YT      V     R DS          + +K +S+  +  +D P    ++ 
Sbjct: 22720 E--KVSLQYTGKRATAVIKFCDRSDSGKYTLTVKNASGTKAVSVMVKV-LDSPGPCGKLT 22776

Query: 1550  VTDVQDNSISVKW-LP---SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPT 1605
             V+ V     ++ W LP     + +T Y V           + +T+  +   + +EG  PT
Sbjct: 22777 VSRVTQEKCTLAWSLPQEDGGAEITHYIV----------ERRETSRLNW--VIVEGECPT 22824

Query: 1606  VEYVVS-----------VYAQNPSG-----ESQPLVQTAVTNIDRPKGL-AFTDVDVDSI 1648
             + YVV+           V A N  G     ES+P+V      I  P G+        + I
Sbjct: 22825 LSYVVTRLIKNNEYIFRVRAVNKYGPGVPVESEPIVARNSFTIPSPPGIPEEVGTGKEHI 22884

Query: 1649  KIAWESPQ----GQVSRYRVTYSSPED----GIHELFPAPDGEEDTAELQGLRPGSEYTV 1700
              I W  P+     ++S Y V     +      +++ +   D      ++  L  G +Y  
Sbjct: 22885 IIQWTKPESDGGNEISNYLVDKREKKSLRWTRVNKDYVVYD---TRLKVTSLMEGCDYQF 22941

Query: 1701  SVVALHDDMESQP------LIGTQSTAIPAPTDL-KFTQVTPTSLSAQWTPP----NVQL 1749
              V A++    S+P      +   + +  P P    +    T  S+S  WT P       +
Sbjct: 22942 RVTAVNAAGNSEPSEASNFISCREPSYTPGPPSAPRVVDTTKHSISLAWTKPMYDGGTDI 23001

Query: 1750  TGYRVRVTPKEKTGPMK-EINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGV- 1807
              GY + +  K+     +   N    ++   V  L +  KY   V A+     S  ++ + 
Sbjct: 23002 VGYVLEMQEKDTDQWYRVHTNATIRNTEFTVPDLKMGQKYSFRVAAVNVKGMSEYSESIA 23061

Query: 1808  -VTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPA-----NGQTPIQRTI 1861
              +  +E +  P    + D  + T+TI        +        P       G     R I
Sbjct: 23062 EIEPVERIEIP-DLELADDLKKTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAI 23120

Query: 1862  KPDVRSYTITGLQPGTDYKIYLYTL---NDNARSSPVVIDASTAIDAP-SNLRFLATTPN 1917
                  SY++  +     Y    YT+   N + + S  V+        P  +++    + +
Sbjct: 23121 IDTTESYSLLIVDKVNRYDAGKYTIEAENQSGKKSATVLVKVYDTPGPCPSVKVKEVSRD 23180

Query: 1918  SLLVSWQPPR----ARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYV 1973
             S+ ++W+ P     A +  YI++  +      + V   +   T   I+GL  GT Y   V
Sbjct: 23181 SVTITWEIPTIDGGAPVNNYIVEKREAAMRAFKTV-TTKCSKTLYRISGLVEGTMYYFRV 23239

Query: 1974  I 1974
             +
Sbjct: 23240 L 23240



 Score =  101 bits (252), Expect = 7e-21
 Identities = 364/1780 (20%), Positives = 631/1780 (35%), Gaps = 317/1780 (17%)

Query: 624   NSHPIQWNAPQPSHISKYILRW---RPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQ 680
             N+  I+W  P     SK I  W   + +N++   KE  +P    +Y + GL  G+ Y+ +
Sbjct: 22483 NAMSIRWEEPYHDGGSKIIGYWVEKKERNTILWVKENKVPCLECNYKVTGLVEGLEYQFR 22542

Query: 681   LISIQQYGHQEVTRFDFTTTSTSTPVTS-NTVTGETTPFSPLVATSESVTEITASSFVVS 739
               ++   G  + +         S P+ + N V     P          VT++T S+  + 
Sbjct: 22543 TYALNAAGVSKASE-------ASRPIMAQNPVDAPGRP---------EVTDVTRSTVSLI 22586

Query: 740   WVSAS----DTVSGFRVEYELSEEGDEPQYLDLPSTATSVN---IPDLLPGRKYIVNVYQ 792
             W + +      V G+ +E +   E  + ++L    T  S N   +  L  G  Y   V  
Sbjct: 22587 WSAPAYDGGSKVVGYIIERKPVSEVGDGRWLKCNYTIVSDNFFTVTALSEGDTYEFRVLA 22646

Query: 793   ISEDGEQSLILSTSQTTAPD------APPDPTVD-QVDDTSIVVRWSRPQAPITGYRIVY 845
              +  G   +I   S++T P       APP   +D ++    + +R         G  +V 
Sbjct: 22647 KNAAG---VISKGSESTGPVTCRDEYAPPKAELDARLHGDLVTIR--------AGSDLVL 22695

Query: 846   SPSVEGS----------STELNLPETANS----------VTLSDLQPGVQYNITIYAVEE 885
               +V G             EL+L E  +           +   D     +Y +T+     
Sbjct: 22696 DAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSGKYTLTVKNASG 22755

Query: 886   NQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDV 941
              +  + +V   ++ G     TV          VT  K T+ W+ P+    + +T Y V+ 
Sbjct: 22756 TKAVSVMVKVLDSPGPCGKLTVS--------RVTQEKCTLAWSLPQEDGGAEITHYIVE- 22806

Query: 942   IPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYY-----------FKVFAVS-HGR----E 985
                        R   SR  +  V G  P ++Y            F+V AV+ +G     E
Sbjct: 22807 -----------RRETSRLNWVIVEGECPTLSYVVTRLIKNNEYIFRVRAVNKYGPGVPVE 22855

Query: 986   SKPLTAQQTTKLDAPTNL-QFVNETDSTVLVRWTPPRA----QITGYRLTVGLTRRGQPR 1040
             S+P+ A+ +  + +P  + + V      ++++WT P +    +I+ Y   V    +   R
Sbjct: 22856 SEPIVARNSFTIPSPPGIPEEVGTGKEHIIIQWTKPESDGGNEISNY--LVDKREKKSLR 22913

Query: 1041  QYNVGPSVSKYPLR----NLQPASEYTVSLVAIK--GNQESPKATGVFTTLQPGSSI-PP 1093
                V      Y  R    +L    +Y   + A+   GN E  +A+   +  +P  +  PP
Sbjct: 22914 WTRVNKDYVVYDTRLKVTSLMEGCDYQFRVTAVNAAGNSEPSEASNFISCREPSYTPGPP 22973

Query: 1094  YNTEVTETT---IVITWTP------APRIGFKLGVRPSQGGEAPR---EVTSDSGSIVVS 1141
                 V +TT   I + WT          +G+ L ++     +  R     T  +    V 
Sbjct: 22974 SAPRVVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDTDQWYRVHTNATIRNTEFTVP 23033

Query: 1142  GLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPD---TGVLTVSWERS 1198
              L  G +Y + +  +      +       + P+       LE   D   T  +       
Sbjct: 23034 DLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEIPDLELADDLKKTVTIRAGASLR 23093

Query: 1199  TTPDITGYRITTTPTNGQQGNSLEEVVHADQS-SCTFDNLSPGLEYNVSVYTVKDDKESV 1257
                 ++G R     T  +QG  L      D + S +   +     Y+   YT++ + +S 
Sbjct: 23094 LMVSVSG-RPPPVITWSKQGIDLASRAIIDTTESYSLLIVDKVNRYDAGKYTIEAENQSG 23152

Query: 1258  PISDTIIPAV----PPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAE 1313
               S T++  V     P   ++   +  D++ +TW  P +ID    +  Y   K E  +  
Sbjct: 23153 KKSATVLVKVYDTPGPCPSVKVKEVSRDSVTITWEIP-TIDGGAPVNNYIVEKREAAMRA 23211

Query: 1314  ---LSISPSDNAVVLTNLLPGTEYVVSV--SSVY---EQHESTPLRGRQKTGLDSPTGID 1365
                ++   S     ++ L+ GT Y   V   ++Y   E  E++      +  L  P  ++
Sbjct: 23212 FKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYGIGEPCETSDAVLVSEVPL-VPAKLE 23270

Query: 1366  FSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRNSI---TLTNL 1418
               D+T ++ T+ W  P     + +TGY +       +G  R  +V   + ++   T+T+L
Sbjct: 23271 VVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACK---AGTERWMKVVTLKPTVLEHTVTSL 23327

Query: 1419  TPGTEYVVSIVALNGREESPLLIGQQSTVSDVP-RDLEVVAATPTSLLISWDAPAVTVRY 1477
               G +Y+  I A N +  S      + TV+ V  +DL V+     S +          R 
Sbjct: 23328 NEGEQYLFRIRAQNEKGVSE----PRETVTAVTVQDLRVLPTIDLSTMPQKTIHVPAGRP 23383

Query: 1478  YRITYGETGGNSPVQEFTVPGSKS-----------------TATISGLKPGVDYTITVYA 1520
               +     G   P   +   GSK                  T   + ++   +YT+ +  
Sbjct: 23384 VELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAKLTIRETTIRDTGEYTLELKN 23443

Query: 1521  VTGRGDSPASSKPISINYRTEIDKPSQ----MQVTDVQDNSISVKWLP----SSSPVTGY 1572
             VTG      +S+ I +     +DKP      +++ ++   SI++ W P      +P++GY
Sbjct: 23444 VTG-----TTSETIKVII---LDKPGPPTGPIKIDEIDATSITISWEPPELDGGAPLSGY 23495

Query: 1573  RVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPL------VQ 1626
              V     + PG      +    T      L    EYV  V A N  G    L       +
Sbjct: 23496 VVEQRDAHRPGWLPVSESVTRST-FKFTRLTEGNEYVFRVAATNRFGIGSYLQSEVIECR 23554

Query: 1627  TAVTNIDRPKGLAFTDVDVDSIKIAWESPQ----GQVSRYRVTYSSPEDGIHELFPAPDG 1682
             +++     P+ L   DV  D + + W  P+     QV+ Y V                  
Sbjct: 23555 SSIRIPGPPETLQIFDVSRDGMTLTWYPPEDDGGSQVTGYIVERKEVRADRWVRVNKVPV 23614

Query: 1683  EEDTAELQGLRPGSEYTVSVVALH------DDMESQPLIGTQSTAIPA-PTDLKFTQVTP 1735
                     GL  G EY   V A++          S+P++     A P  P + + T  T 
Sbjct: 23615 TMTRYRSTGLTEGLEYEHRVTAINARGSGKPSRPSKPIVAMDPIAPPGKPQNPRVTDTTR 23674

Query: 1736  TSLSAQWTPPNVQ----LTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVS 1791
             TS+S  W+ P  +    +TGY + +   ++    K            ++ L    +Y   
Sbjct: 23675 TSVSLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTKCNTTPTKIREYTLTHLPQGAEYRFR 23734

Query: 1792  VYALKDTLTSRPAQ--GVVTTLENVSPP---------RRARVTDATETTITISWRTKTET 1840
             V A        PA+  G V   E +  P             V       +TI  + K   
Sbjct: 23735 VLACNAGGPGEPAEVPGTVKVTEMLEYPDYELDERYQEGIFVRQGGVIRLTIPIKGKP-- 23792

Query: 1841  ITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGT--DYKIYLYTLNDNARSSPVVID 1898
                F +      GQ   +R +     ++T   ++     D   Y   L +      V I 
Sbjct: 23793 ---FPICKWTKEGQDISKRAMIATSETHTELVIKEADRGDSGTYDLVLENKCGKKAVYIK 23849

Query: 1899  ASTAIDAPSN----LRFLATTPNSLLVSWQPPR----ARITGYII-KYEKPGSPPREVVP 1949
                 I +P++    L +      S+ VSW+PP     A I GYI+ + E P +    +  
Sbjct: 23850 VRV-IGSPNSPEGPLEYDDIQVRSVRVSWRPPADDGGADILGYILERREVPKAAWYTIDS 23908

Query: 1950  RPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQKTPFVTHPGYDTGNGI 2009
             R R   T   + GL+   EY   V A      S+PL   +    KTP             
Sbjct: 23909 RVRG--TSLVVKGLKENVEYHFRVSAENQFGISKPLKSEEPVTPKTPL------------ 23954

Query: 2010  QLPGTSGQQPSVGQQMIFEEHGFRRTTPPTTATPIRHRPRPYPPNVGQEALSQTTISWAP 2069
                                        PP         P   PP V     S  ++SW+ 
Sbjct: 23955 --------------------------NPP--------EPPSNPPEVLDVTKSSVSLSWSR 23980

Query: 2070  FQD-----TSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKD--- 2121
              +D      + Y I      TD+     +   T+T  T+TGL   A Y   + A  D   
Sbjct: 23981 PKDDGGSRVTGYYIERKETSTDKWVRHNKTQITTTMYTVTGLVPDAEYQFRIIAQNDVGL 24040

Query: 2122  QQRHKVREEVVTVGNSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLG 2181
              +     E VV       +  ++P+     +  ++S  +V  +WE+    G K   + LG
Sbjct: 24041 SETSPASEPVV-----CKDPFDKPSQPGELEILSISKDSVTLQWEKPECDGGK---EILG 24092

Query: 2182  FGSGHFRCDSSRWCHDNGVNYKIGEKWDRQGENGQMMSCT 2221
             +   + +   S W   N    K     D+Q   G ++  T
Sbjct: 24093 YWVEYRQSGDSAWKKSNKERIK-----DKQFTIGGLLEAT 24127



 Score = 99.8 bits (247), Expect = 3e-20
 Identities = 305/1551 (19%), Positives = 537/1551 (34%), Gaps = 252/1551 (16%)

Query: 610   GPVEVFITETPSQPNSHPIQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSY 666
             GPV        ++ + H + W  P+    S ++ YI+  R  +    W   T      S+
Sbjct: 12328 GPVSDLKVSDVTKTSCH-VSWAPPENDGGSQVTHYIVEKREADRK-TWSTVTPEVKKTSF 12385

Query: 667   TIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSE 726
              +  L PG  Y  ++ ++ +YG           T    PV ++    E  P   L     
Sbjct: 12386 HVTNLVPGNEYYFRVTAVNEYG-------PGVPTDVPKPVLASDPLSEPDPPRKL----- 12433

Query: 727   SVTEITASSFVVSWV----SASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLP 782
              VTE+T +S  ++W+         + G+   Y   E+  +           S+ +  L  
Sbjct: 12434 EVTEMTKNSATLAWLPPLRDGGAKIDGYITSYREEEQPADRWTEYSVVKDLSLVVTGLKE 12493

Query: 783   GRKY-----IVNVYQISEDGEQSLILSTSQTTAPD---APPDPTVDQVDDTSIVVRWSRP 834
             G+KY       N   +S   E   +    +   P     P   T+       I       
Sbjct: 12494 GKKYKFRVAARNAVGVSLPREAEGVYEAKEQLLPPKILMPEQITIKAGKKLRIEAHVYGK 12553

Query: 835   QAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDL--QPGVQYNITIYAVEENQESTPV 892
               P   ++      V  S   ++  ++++ + + D+  +    Y++T             
Sbjct: 12554 PHPTCKWKKGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIK 12613

Query: 893   VIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPG 948
             V+  +  G P+      P D+  ++      ++ W  P     S +T Y V+   V+  G
Sbjct: 12614 VVVMDAPGPPQ-----PPFDISDIDAD--ACSLSWHIPLEDGGSNITNYIVEKCDVS-RG 12665

Query: 949   EHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKL------DAPTN 1002
             +    L     T   V  L PG  Y F+V A +    S+PLT+ +            P N
Sbjct: 12666 DWVTALASVTKTSCRVGKLIPGQEYIFRVRAENRFGISEPLTSPKMVAQFPFGVPSEPKN 12725

Query: 1003  LQFVNETDSTVLVRWTPPRAQ----ITGYRLTVGLTRRGQPRQYNVGPSV---SKYPLRN 1055
              +        + V W  P +     I GY   +    R          ++   ++YP   
Sbjct: 12726 ARVTKVNKDCIFVAWDRPDSDGGSPIIGY--LIERKERNSLLWVKANDTLVRSTEYPCAG 12783

Query: 1056  LQPASEYTVSLVAIKGNQESP--KATGVFTTLQPGSSIPPYNTE---VTETTIVITWT-P 1109
             L    EY+  + A+     SP  K T   T   P    PP   E   VT++T+ + W  P
Sbjct: 12784 LVEGLEYSFRIYALNKAGSSPPSKPTEYVTARMPVD--PPGKPEVIDVTKSTVSLIWARP 12841

Query: 1110  APRIGFKL-----------GVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVY------- 1151
                 G K+           G +  +   AP ++  +      +GL    +Y +       
Sbjct: 12842 KHDGGSKIIGYFVEACKLPGDKWVRCNTAPHQIPQE--EYTATGLEEKAQYQFRAIARTA 12899

Query: 1152  -------------TIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANP-DTGVLTVSWER 1197
                          TI         D  +  K +  +   TN+ L+A      + TVSW++
Sbjct: 12900 VNISPPSEPSDPVTILAENVPPRIDLSVAMKSLLTVKAGTNVCLDATVFGKPMPTVSWKK 12959

Query: 1198  STTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFD----NLSPGLEYNVSVYTVKDD 1253
               T           P  G +       +   ++ CT +    N     +Y ++       
Sbjct: 12960 DGT--------LLKPAEGIK-------MAMQRNLCTLELFSVNRKDSGDYTITAENSSGS 13004

Query: 1254  KESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPP---PSIDLTNFLVRYSPVKNEED 1310
             K S  I   ++    PP  ++   +  D   ++W PP      ++TN++V      +  +
Sbjct: 13005 K-SATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYIVDKRET-SRPN 13062

Query: 1311  VAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPL---RGRQKTGLDSPTGID-- 1365
              A++S +    +  +  L+ G EY   + +  +     P+       K   D P   D  
Sbjct: 13063 WAQVSATVPITSCSVEKLIEGHEYQFRICAENKYGVGDPVFTEPAIAKNPYDPPGRCDPP 13122

Query: 1366  -FSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTP 1420
               S+IT +  TV W  P     + ITGY +           + +R P    ++  T L  
Sbjct: 13123 VISNITKDHMTVSWKPPADDGGSPITGYLLEKRETQAVNWTKVNRKPIIERTLKATGLQE 13182

Query: 1421  GTEYVVSIVALNGREESPLLIGQQSTVSDV------------PRDLEVVAATPTSLLISW 1468
             GTEY   + A+N  +  P   G+ S  S              P   +V   T +S+ +SW
Sbjct: 13183 GTEYEFRVTAIN--KAGP---GKPSDASKAAYARDPQYPPGPPAFPKVYDTTRSSVSLSW 13237

Query: 1469  DAPAV----TVRYYRITYGETGGNSPVQEFTVPGS--KSTATISGLKPGVDYTITVYAVT 1522
               PA      +  Y +       ++ V+   +P +  K+   ++GL     Y   VYAV 
Sbjct: 13238 GKPAYDGGSPIIGYLVEVKRADSDNWVR-CNLPQNLQKTRFEVTGLMEDTQYQFRVYAVN 13296

Query: 1523  GRG-----DSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTT 1577
               G     D P    P  I    E +  + ++ T +    ++++      PV G      
Sbjct: 13297 KIGYSDPSDVPDKHYPKDILIPPEGELDADLRKTLILRAGVTMRLY---VPVKGRPPPKI 13353

Query: 1578  PKNGPGPTKTKTAGPD------QTEMTIEGLQ--PTVEYVVSVYAQNPSGESQPLVQTAV 1629
               + P        G D       T +  E +      +Y++++  +N  G+ +  +   V
Sbjct: 13354 TWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKYILTL--ENSCGKKEYTIVVKV 13411

Query: 1630  TNIDRPK-GLAFTDVDVDSIKIAWESP----QGQVSRYRVTYSSPEDGIHELFPAPDGEE 1684
              +   P   +   ++  DS  + WE P       +  Y V     E          +  +
Sbjct: 13412 LDTPGPPVNVTVKEISKDSAYVTWEPPIIDGGSPIINYVVQKRDAERKSWSTV-TTECSK 13470

Query: 1685  DTAELQGLRPGSEYTVSVVA-----LHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLS 1739
              +  +  L  G  Y   V A     + D  E++  +    T  P   DLK   V+ +S S
Sbjct: 13471 TSFRVANLEEGKSYFFRVFAENEYGIGDPGETRDAVKASQTPGPV-VDLKVRSVSKSSCS 13529

Query: 1740  AQWTPPN----VQLTGYRVRVTPKEKTGP--MKEINLAPDSSSVVVSGLMVATKYEVSVY 1793
               W  P+     ++ GY V    +E      MK ++L   +       L    +Y   V 
Sbjct: 13530 IGWKKPHSDGGSRIIGYVVDFLTEENKWQRVMKSLSLQYSAKD-----LTEGKEYTFRVS 13584

Query: 1794  ALKDTLTSRPAQGVVTTLENVSPPR-------------------RARVTDATETTITISW 1834
             A  +     P++  V   ++V  P                    R ++    +   ++SW
Sbjct: 13585 AENENGEGTPSEITVVARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPIKGKPAPSVSW 13644

Query: 1835  RTKTE---TITGFQVDAVPANGQTPIQRTIKPDVRSYTIT-----GLQPGTDYKIYLYTL 1886
             +   +   T T   V++   N    +    K D   YTIT     G + GT         
Sbjct: 13645 KKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKEGT--------- 13695

Query: 1887  NDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGS 1942
                   S  V+        P  ++F   T  ++ + W PP+    + IT YI++ ++   
Sbjct: 13696 -----ISIKVVGKPGIPTGP--IKFDEVTAEAMTLKWAPPKDDGGSEITNYILE-KRDSV 13747

Query: 1943  PPREVVPRPRPGVTEATITGLEPGTEYTIYVIA-----LKNNQKSEPLIGR 1988
               + V        T   +T L  G EYT  V A     +    KSEP++ R
Sbjct: 13748 NNKWVTCASAVQKTTFRVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVAR 13798



 Score = 96.7 bits (239), Expect = 2e-19
 Identities = 334/1533 (21%), Positives = 553/1533 (36%), Gaps = 218/1533 (14%)

Query: 619   TPSQPNSHPIQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGV 675
             T S  +S  +QWN P     S +  Y L  + +NS+   K    P     +   GL+ GV
Sbjct: 15978 TLSSRDSMEVQWNEPISDGGSRVIGYHLERKERNSILWVKLNKTPIPQTKFKTTGLEEGV 16037

Query: 676   VYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASS 735
              YE ++ +    G                P   +       P  P     E++  +T +S
Sbjct: 16038 EYEFRVSAENIVG-------------IGKPSKVSECYVARDPCDP-PGRPEAII-VTRNS 16082

Query: 736   FVVSW----VSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVY 791
               + W          ++G+ VE +   EG   +        T   +  L+   +Y   V 
Sbjct: 16083 VTLQWKKPTYDGGSKITGYIVEKKELPEGRWMKASFTNIIDTHFEVTGLVEDHRYEFRVI 16142

Query: 792   QISEDGEQSLIL-STSQTTAPDA--PPDPTVDQVDDTSIVVRWS---RPQAPITGYRIVY 845
               +  G  S    ST   TA D   PP  ++D     +IVV      +  A I G  I  
Sbjct: 16143 ARNAAGVFSEPSESTGAITARDEVDPPRISMDPKYKDTIVVHAGESFKVDADIYGKPI-- 16200

Query: 846   SPSVEGSSTELNLPETAN-SVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRS 904
              P+++    +  L  TA   +  +D    +     +       +S   +++ +     RS
Sbjct: 16201 -PTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRV-----DSGNYILKAKNVAGERS 16254

Query: 905   DTV-------PSPRDLQFV--EVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLP 955
              TV       P P +   V   VT  K T+ W PP   +     D+I   +      RL 
Sbjct: 16255 VTVNVKVLDRPGPPEGPVVISGVTAEKCTLAWKPP---LQDGGSDIINYIVERRETSRLV 16311

Query: 956   IS------RNTFAEVTGLSPGVTYYFKVFAVS-----HGRESKPLTAQQTTKL-DAPTNL 1003
              +      +    +VT L  G  Y F++ AV+        ES+P+ A+    + DAP   
Sbjct: 16312 WTVVDANVQTLSCKVTKLLEGNEYTFRIMAVNKYGVGEPLESEPVVAKNPFVVPDAPKAP 16371

Query: 1004  QFVNETDSTVLVRWTPPRA----QITGYRLTV----GLTRRGQPRQYNVGPSVSKYPLRN 1055
             +    T  +++V W  P +    +I GY L      G+ R  +  +  +G    +     
Sbjct: 16372 EVTTVTKDSMIVVWERPASDGGSEILGYVLEKRDKEGI-RWTRCHKRLIGELRLRVTGLI 16430

Query: 1056  LQPASEYTVSLVAIKGNQE-SPKAT---GVFTTLQPGSSIPPYNTEVTETTIVITWTPAP 1111
                  E+ VS     G  E SP +          +PG    P   ++T +++ ++W+   
Sbjct: 16431 ENHDYEFRVSAENAAGLSEPSPPSAYQKACDPIYKPGPPNNPKVIDITRSSVFLSWSKPI 16490

Query: 1112  RIGF---------KLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRD---G 1159
               G          K  V   +          +  +I V  L    EY + I  +     G
Sbjct: 16491 YDGGCEIQGYIVEKCDVSVGEWTMCTPPTGINKTNIEVEKLLEKHEYNFRICAINKAGVG 16550

Query: 1160  QERDAPIVNKVVTPL-SPPTNLHLEANPDTGV-------LTVSWERSTTPDITGYRITTT 1211
             +  D P    V   L +P  +L LE      +       L V  +   TP++   ++   
Sbjct: 16551 EHADVPGPIIVEEKLEAPDIDLDLELRKIINIRAGGSLRLFVPIKGRPTPEVKWGKV--- 16607

Query: 1212  PTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTV----KDDKESVPISDTIIPAV 1267
               +G+  ++    V +  +S   DN++    Y+   YT+        +S  ++  ++   
Sbjct: 16608 --DGEIRDAAIIDVTSSFTSLVLDNVN---RYDSGKYTLTLENSSGTKSAFVTVRVLDTP 16662

Query: 1268  PPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNE---EDVAELSISPSDNAVV 1324
              PP +L+ T I  D++ +TW  PP +D  + +  Y   K E   +  A +  +   N+  
Sbjct: 16663 SPPVNLKVTEITKDSVSITW-EPPLLDGGSKIKNYIVEKREATRKSYAAVVTNCHKNSWK 16721

Query: 1325  LTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGL----DSPTGIDFSDITANSFTVHWIA 1380
             +  L  G  Y   V++  E     P +      +      P  I   D+T NS ++ W  
Sbjct: 16722 IDQLQEGCSYYFRVTAENEYGIGLPAQTADPIKVAEVPQPPGKITVDDVTRNSVSLSWTK 16781

Query: 1381  PR----ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREE 1436
             P     + I  Y +    +H        RV   +    +TNLT G EY+  +VA+N +  
Sbjct: 16782 PEHDGGSKIIQYIVEMQAKHSEKWSECARVKSLQ--AVITNLTQGEEYLFRVVAVNEKGR 16839

Query: 1437  S-PLLIGQQSTVSDVPRDLEVVAA-TPTSLLISWD----APAVTVRYYRITYGETGGNSP 1490
             S P  +       D+  + +V  A +  S+ +  D     P        IT+ + G   P
Sbjct: 16840 SDPRSLAVPIVAKDLVIEPDVKPAFSSYSVQVGQDLKIEVPISGRPKPTITWTKDG--LP 16897

Query: 1491  VQEFT---VPGSKSTATIS----GLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEID 1543
             +++ T   V  S    T+S        G  Y ITV  V G+       K  SI   T +D
Sbjct: 16898 LKQTTRINVTDSLDLTTLSIKETHKDDGGQYGITVANVVGQ-------KTASIEIVT-LD 16949

Query: 1544  KP----SQMQVTDVQDNSISVKWLP----SSSPVTGYRV-----TTTPKNGPGPTKTKTA 1590
             KP      ++  DV   SI++ W P        +T Y V     TTT  +    T  +T 
Sbjct: 16950 KPDPPKGPVKFDDVSAESITLSWNPPLYTGGCQITNYIVQKRDTTTTVWDVVSATVARTT 17009

Query: 1591  GPDQTEMTIEGLQPTVEYVVSVYAQNPSG-----ESQPLVQTAVTNIDRPKGLAF-TDVD 1644
                   + +  L+   EY   ++A+N  G     ES P+V         P G  F T + 
Sbjct: 17010 ------LKVTKLKTGTEYQFRIFAENRYGQSFALESDPIVAQYPYKEPGPPGTPFATAIS 17063

Query: 1645  VDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGE---EDTA-ELQGLRPGSEYTV 1700
              DS+ I W  P        + Y       + +      +    DT  + Q L  G EY  
Sbjct: 17064 KDSMVIQWHEPVNNGGSPVIGYHLERKERNSILWTKVNKTIIHDTQFKAQNLEEGIEYEF 17123

Query: 1701  SVVALHDDMESQPLIGTQSTAIPAPTDLKFT----QVTPTSLSAQWTPP----NVQLTGY 1752
              V A +     +    ++      P D   T     V    ++ QWT P       +TGY
Sbjct: 17124 RVYAENIVGVGKASKNSECYVARDPCDPPGTPEPIMVKRNEITLQWTKPVYDGGSMITGY 17183

Query: 1753  RVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDT-LTSRPAQ--GVVT 1809
              V          MK        +   VSGL    +YE  V A       S+P+   G +T
Sbjct: 17184 IVEKRDLPDGRWMKASFTNVIETQFTVSGLTEDQRYEFRVIAKNAAGAISKPSDSTGPIT 17243

Query: 1810  TLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYT 1869
               + V  PR +      +T +  +  T       F+++A       P    ++ D     
Sbjct: 17244 AKDEVELPRISMDPKFRDTIVVNAGET-------FRLEADVHGKPLPTIEWLRGDKEIEE 17296

Query: 1870  ITGLQ-PGTDYKIYL------------YTLNDN----ARSSPV---VIDASTAIDAPSNL 1909
                 +   TD+K  L            Y L  +    ++S PV   V+D     + P  +
Sbjct: 17297 SARCEIKNTDFKALLIVKDAIRIDGGQYILRASNVAGSKSFPVNVKVLDRPGPPEGP--V 17354

Query: 1910  RFLATTPNSLLVSWQPP----RARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEP 1965
             +    T     ++W PP     + I+ Y+++ ++  S     V           +T L  
Sbjct: 17355 QVTGVTSEKCSLTWSPPLQDGGSDISHYVVE-KRETSRLAWTVVASEVVTNSLKVTKLLE 17413

Query: 1966  GTEYTIYVIALKNNQKSEPLIGRKKTVQKTPFV 1998
             G EY   ++A+      EPL      + K PFV
Sbjct: 17414 GNEYVFRIMAVNKYGVGEPL-ESAPVLMKNPFV 17445



 Score = 93.6 bits (231), Expect = 2e-18
 Identities = 287/1440 (19%), Positives = 522/1440 (36%), Gaps = 175/1440 (12%)

Query: 675   VVYEGQLISIQQYGHQEVTRFDFTTTSTS--TPVTSNTVTGETT--PFSPLVATSESVTE 730
             +  E   I++++    +  R++ T  ++S  T    N V  +    P  P+V     +++
Sbjct: 20155 ITAENLTINLKESVTADAGRYEITAANSSGTTKAFINIVVLDRPGPPTGPVV-----ISD 20209

Query: 731   ITASSFVVSWVSAS-DTVSGFRVEYELSEEGDEPQYLDLPSTA--TSVNIPDLLPGRKY- 786
             IT  S  + W     D  S       L  E     + ++ +T   T + +  L  G +Y 
Sbjct: 20210 ITEESVTLKWEPPKYDGGSQVTNYILLKRETSTAVWTEVSATVARTMMKVMKLTTGEEYQ 20269

Query: 787   ----IVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYR 842
                   N + IS+  + + +      T P  P  P V  V   SI V W  P +   G  
Sbjct: 20270 FRIKAENRFGISDHIDSACVTVKLPYTTPGPPSTPWVTNVTRESITVGWHEPVS--NGGS 20327

Query: 843   IVYSPSVEGSSTELNLPETANSVTL-------SDLQPGVQYNITIYAVEENQESTPVVIQ 895
              V    +E       L + AN + +       + +  G+ Y   +YA        P    
Sbjct: 20328 AVVGYHLEMKDRNSILWQKANKLVIRTTHFKVTTISAGLIYEFRVYAENAAGVGKP---S 20384

Query: 896   QETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPVNLPGEHG 951
               +      D    PR+++  +++   V++ W  P     S +TGY V+    +LP    
Sbjct: 20385 HPSEPVLAIDACEPPRNVRITDISKNSVSLSWQQPAFDGGSKITGYIVE--RRDLPDGRW 20442

Query: 952   QRLPISRNTFAE--VTGLSPGVTYYFKVFAVSH-GRESKPL-TAQQTTKLDAPTNLQFVN 1007
              +   +  T  +  ++GL+    Y F+VFA +  G  S P       T +D+        
Sbjct: 20443 TKASFTNVTETQFIISGLTQNSQYEFRVFARNAVGSISNPSEVVGPITCIDSYGGPVIDL 20502

Query: 1008  ETDSTVLVRWTPPRAQITGYRLTVGLTRRGQP--RQYNVGPSVSKYPLRNLQPASEYTVS 1065
               + T +V++       T  +L  G++ +  P    Y     +    L  ++  ++    
Sbjct: 20503 PLEYTEVVKYRAG----TSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLASI 20558

Query: 1066  LV-------------AIKGNQESPKATGVFTTL-QPGSSIPPYNTE-VTETTIVITW-TP 1109
             L+              ++    S  AT     L +PG    P   + VT   I + W  P
Sbjct: 20559 LIKDADRLNSGCYELKLRNAMGSASATIRVQILDKPGPPGGPIEFKTVTAEKITLLWRPP 20618

Query: 1110  APRIGFKLGVRPSQGGEAPREVTS------DSGSIVVSGLTPGVEYVYTIQVLR-----D 1158
             A   G K+     +  E  R V S      +   I  + +  G EY++ ++ +      +
Sbjct: 20619 ADDGGAKITHYIVEKRETSRVVWSMVSEHLEECIITTTKIIKGNEYIFRVRAVNKYGIGE 20678

Query: 1159  GQERDAPIV-NKVVTPLSP--PTNLHLEANPDTGVLTVSWERSTT---PDITGYRITTTP 1212
               E D+ +  N  VTP  P  P    +  N     +TV W R       DI+GY +    
Sbjct: 20679 PLESDSVVAKNAFVTPGPPGIPEVTKITKNS----MTVVWSRPIADGGSDISGYFLEKRD 20734

Query: 1213  TNGQQG-NSLEEVVHADQSSCTFDNLSPGLEYNVSVYTV--------KDDKESVPISDTI 1263
                      L+E +   +   T   L+   +Y   V  V         +  E    +D I
Sbjct: 20735 KKSLGWFKVLKETIRDTRQKVT--GLTENSDYQYRVCAVNAAGQGPFSEPSEFYKAADPI 20792

Query: 1264  IPAVPPPTDLRFTNIGPDTMRVTWAPP---PSIDLTNFLVRYSPVKNEE-DVAELSISPS 1319
              P   PP  +R  +    ++ + W+ P       +T ++V     + EE           
Sbjct: 20793 DPP-GPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVVEIRQGEEEEWTTVSTKGEVR 20851

Query: 1320  DNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQ----KTGLDSPTGIDFSDITANSFT 1375
                 V++NL PG  Y   VS+V    +  P+   +    K  L++P  ID       S  
Sbjct: 20852 TTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQAKDILEAPE-IDLDVALRTSVI 20910

Query: 1376  VHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSI---------TLTNLTPGT--EY 1424
                      +  ++ R  P     +  ++    +R SI         T+  +T     +Y
Sbjct: 20911 AKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKY 20970

Query: 1425  VVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGE 1484
             +++I    G  +S  +  +        + L+V   +  ++ + WD P +      I Y  
Sbjct: 20971 ILTIENGVGEPKSSTVSVKVLDTPAACQKLQVKHVSRGTVTLLWDPPLIDGGSPIINYVI 21030

Query: 1485  TGGNSPVQEFTVPGSKSTATISGL-----KPGVDYTITVYAVTGRGDSPASSKPISINYR 1539
                ++  + ++V   K ++T   L     K    + +      G G+   +++P+     
Sbjct: 21031 EKRDATKRTWSVVSHKCSSTSFKLIDLSEKTPFFFRVLAENEIGIGEPCETTEPVK---A 21087

Query: 1540  TEIDKP-SQMQVTDVQDNSISVKW----LPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQ 1594
              E+  P   + + D    S+ + W        S +T Y V    + G G      AG  +
Sbjct: 21088 AEVPAPIRDLSMKDSTKTSVILSWTKPDFDGGSVITEYVV---ERKGKGEQTWSHAGISK 21144

Query: 1595  T-EMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFT-DVDVDSIKIAW 1652
             T E+ +  L+        V+A+N  G S P+    +T     K L  T +VD+  I  A 
Sbjct: 21145 TCEIEVSQLKEQSVLEFRVFAKNEKGLSDPVTIGPIT----VKELIITPEVDLSDIPGAQ 21200

Query: 1653  ESPQ-GQVSRYRVTY-SSPEDGIHEL---FPAPDGE-------EDTAELQGLRPGSEYTV 1700
              + + G      + Y   P+  I  L    P  + E       E+   L       E+  
Sbjct: 21201 VTVRIGHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGG 21260

Query: 1701  SVVALHDDMESQPLIGTQSTAIPAPT----DLKFTQVTPTSLSAQWTPP----NVQLTGY 1752
                 + D+   +  +      +  P+     ++F ++   S+   W  P      ++T Y
Sbjct: 21261 KYTVILDNAVCRIAVPITVITLGPPSKPKGPIRFDEIKADSVILSWDVPEDNGGGEITCY 21320

Query: 1753  RVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLE 1812
              +      +T   K +  +   ++  V  L+   +Y+  V A      S+P    +   +
Sbjct: 21321 SIEKRETSQTN-WKMVCSSVARTTFKVPNLVKDAEYQFRVRAENRYGVSQPLVSSIIVAK 21379

Query: 1813  N----VSPPRRARVTDATETTITISWRTKT----ETITGFQVDAVPANGQTPIQRTIKP- 1863
             +      PP +  + + T   ++++W          +TGF V+    N     +    P 
Sbjct: 21380 HQFRIPGPPGKPVIYNVTSDGMSLTWDAPVYDGGSEVTGFHVEKKERNSILWQKVNTSPI 21439

Query: 1864  DVRSYTITGLQPGTDYKIYLYTLNDNARSSP----VVIDASTAIDAPSNLRFLATTPNSL 1919
               R Y  TGL  G DY+  +Y  N    SSP        A + +D P    ++  T  ++
Sbjct: 21440 SGREYRATGLVEGLDYQFRVYAENSAGLSSPSDPSKFTLAVSPVDPPGTPDYIDVTRETI 21499

Query: 1920  LVSWQPP----RARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIA 1975
              + W PP     ++I GY I+ ++ G+              + T+TGL PG  Y   +IA
Sbjct: 21500 TLKWNPPLRDGGSKIVGYSIE-KRQGNERWVRCNFTDVSECQYTVTGLSPGDRYEFRIIA 21558



 Score = 92.8 bits (229), Expect = 3e-18
 Identities = 271/1344 (20%), Positives = 470/1344 (34%), Gaps = 199/1344 (14%)

Query: 628   IQWNAPQPS---HISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISI 684
             I W  P  +    IS YI+  R   +   W   +      +  I  LK G  Y+ ++ + 
Sbjct: 18052 ISWEPPAYTGGCQISNYIVEKRDTTTT-TWHMVSATVARTTIKITKLKTGTEYQFRIFAE 18110

Query: 685   QQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSAS 744
              +YG              S P+ S  V  +     P    +  VT I+    +V W    
Sbjct: 18111 NRYGK-------------SAPLDSKAVIVQYPFKEPGPPGTPFVTSISKDQMLVQWHEPV 18157

Query: 745   DTVSGFRVEYELSE-EGDEPQYLDLPSTA---TSVNIPDLLPGRKYI--VNVYQISEDGE 798
             +      + Y L + E +   ++ L  T    T      L  G +Y   V+   I   G+
Sbjct: 18158 NDGGTKIIGYHLEQKEKNSILWVKLNKTPIQDTKFKTTGLDEGLEYEFKVSAENIVGIGK 18217

Query: 799   QSLILSTSQTTAPDAPPD-PTVDQVDDTSIVVRWSRPQ----APITGYRIVYSPSVEG-- 851
              S +        P  PP  P    +   ++ ++W +P     + ITGY +      +G  
Sbjct: 18218 PSKVSECFVARDPCDPPGRPEAIVITRNNVTLKWKKPAYDGGSKITGYIVEKKDLPDGRW 18277

Query: 852   -SSTELNLPETANSVTLSDLQPGVQYNITIYA------VEENQESTPVVIQQETTGTPRS 904
               ++  N+ ET    T+S L    +Y   + A        E  +S+  +  ++    P +
Sbjct: 18278 MKASFTNVLET--EFTVSGLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARDEIDAPNA 18335

Query: 905   DTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPG----EHGQRLPISRNT 960
                P  +D+  V   +  V       E+ + G  +  +  +  G    E   R+ I ++T
Sbjct: 18336 SLDPKYKDVIVVHAGETFVL------EADIRGKPIPDVVWSKDGKELEETAARMEI-KST 18388

Query: 961   FAEVTGL------SPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTN-LQFVNETDSTV 1013
               + T +      + G  Y  K+  V  G +S P+T +   +   P   L+    T    
Sbjct: 18389 IQKTTLVVKDCIRTDGGQYILKLSNVG-GTKSIPITVKVLDRPGPPEGPLKVTGVTAEKC 18447

Query: 1014  LVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAI 1069
              + W PP     A I+ Y +    T R    Q +       Y +  L P +EY   ++A+
Sbjct: 18448 YLAWNPPLQDGGANISHYIIEKRETSRLSWTQVSTEVQALNYKVTKLLPGNEYIFRVMAV 18507

Query: 1070  -KGNQESPKATGVFTTLQP----GSSIPPYNTEVTETTIVITWTP------APRIGFKLG 1118
              K     P  +G  T   P    G    P  + +T+ ++V+TW            G+ L 
Sbjct: 18508 NKYGIGEPLESGPVTACNPYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILE 18567

Query: 1119  VRPSQGGEAPR--EVTSDSGSIVVSGLTPGVEYVYTIQVLRD---GQERDAPIVNKVVTP 1173
              R  +G    +  + T     + V+GLT G  Y + +        G+  +  +  +    
Sbjct: 18568 KRDKEGVRWTKCNKKTLTDLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRACDA 18627

Query: 1174  LSPPTNLHLEANPDTGVLTVS--WERSTTPD---ITGYRI-----------TTTPTNGQQ 1217
             L PP         DT   +VS  W +        + GY +           T TP  G Q
Sbjct: 18628 LYPPGPPSNPKVTDTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAADEWTTCTPPTGLQ 18687

Query: 1218  GNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDD----KESVPISDTIIPAVPPP--- 1270
             G              T   L    EYN  +  +  +      ++P S      + PP   
Sbjct: 18688 GKQF-----------TVTKLKENTEYNFRICAINSEGVGEPATLPGSVVAQERIEPPEIE 18736

Query: 1271  --TDLRFTNI--GPDTMR----VTWAPPPSIDLTNFLVRYSPVKNE-EDVAELSISPSDN 1321
                DLR   +     T+R    +   P P        V++   +    D A++ ++ S  
Sbjct: 18737 LDADLRKVVVLRASATLRLFVTIKGRPEPE-------VKWEKAEGILTDRAQIEVTSSFT 18789

Query: 1322  AVVLTNLLPGTEYVVSVSSVYEQHESTP-LRGRQKTGLDSPTGIDFSDITANSFTVHWIA 1380
              +V+ N+        +++        T  +  R      +P  +   ++  +S T+ W  
Sbjct: 18790 MLVIDNVTRFDSGRYNLTLENNSGSKTAFVNVRVLDSPSAPVNLTIREVKKDSVTLSWEP 18849

Query: 1381  PR----ATITGYRIRHHPEHFSGRPREDRVPHS--RNSITLTNLTPGTEYVVSIVALNGR 1434
             P     A IT Y +       + R     + ++  + +  + NL  G  Y   ++A N  
Sbjct: 18850 PLIDGGAKITNYIVEKRE---TTRKAYATITNNCTKTTFRIENLQEGCSYYFRVLASNEY 18906

Query: 1435  EES-PLLIGQQSTVSDVPRD---LEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSP 1490
                 P    +   VS+ P     + +V  T  +  I W+ P            E+ G S 
Sbjct: 18907 GIGLPAETTEPVKVSEPPLPPGRVTLVDVTRNTATIKWEKP------------ESDGGSK 18954

Query: 1491  VQEFTVP----GSKS----------TATISGLKPGVDYTITVYAVTGRGDSPASSKPISI 1536
             +  + V     GS+            ATISGL  G +Y   V AV  +G S      + +
Sbjct: 18955 ITGYVVEMQTKGSEKWSTCTQVKTLEATISGLTAGEEYVFRVAAVNEKGRSDPRQLGVPV 19014

Query: 1537  NYRTEIDKPSQMQVTDVQDNSISVK---WLPSSSPVTGYRVTTTPKNGPGPTKTKT---- 1589
               R    KPS     ++  ++ +VK    L    P  G    T      G T  +T    
Sbjct: 19015 IARDIEIKPS----VELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVN 19070

Query: 1590  --AGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKG-LAFTDVDVD 1646
               +    T ++I+           +   N +G     +   V +   P G +   +V  D
Sbjct: 19071 VSSSKTVTSLSIKEASKEDVGTYELCVSNSAGSITVPITIIVLDRPGPPGPIRIDEVSCD 19130

Query: 1647  SIKIAWESPQ----GQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSV 1702
             SI I+W  P+     Q+S Y V           +  +      + ++  L  GSEY   V
Sbjct: 19131 SITISWNPPEYDGGCQISNYIVEKKETTSTTWHIV-SQAVARTSIKIVRLTTGSEYQFRV 19189

Query: 1703  VALH-----DDMESQPLIGTQSTAIPAPTDL-KFTQVTPTSLSAQWTPP----NVQLTGY 1752
              A +        ES  ++     + P P    K    T +++   W  P      ++ GY
Sbjct: 19190 CAENRYGKSSYSESSAVVAEYPFSPPGPPGTPKVVHATKSTMLVTWQVPVNDGGSRVIGY 19249

Query: 1753  RVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGV--VTT 1810
              +    +      K   +    + + VSGL     YE  VYA       + ++    V  
Sbjct: 19250 HLEYKERSSILWSKANKILIADTQMKVSGLDEGLMYEYRVYAENIAGIGKCSKSCEPVPA 19309

Query: 1811  LENVSPPRRARVTDATETTITISW 1834
              +   PP +  VT+ T  ++++ W
Sbjct: 19310 RDPCDPPGQPEVTNITRKSVSLKW 19333



 Score = 92.0 bits (227), Expect = 6e-18
 Identities = 265/1345 (19%), Positives = 470/1345 (34%), Gaps = 186/1345 (13%)

Query: 814   PPDPTVD--QVDDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTL 867
             PP P  D   +D  +  + W  P     + IT Y +       G         T  S  +
Sbjct: 12622 PPQPPFDISDIDADACSLSWHIPLEDGGSNITNYIVEKCDVSRGDWVTALASVTKTSCRV 12681

Query: 868   SDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPS-PRDLQFVEVTDVKVTIM 926
               L PG +Y   + A      S P+   +     P    VPS P++ +  +V    + + 
Sbjct: 12682 GKLIPGQEYIFRVRAENRFGISEPLTSPKMVAQFPFG--VPSEPKNARVTKVNKDCIFVA 12739

Query: 927   WTPPES----AVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSH 982
             W  P+S     + GY ++    N          + R+T     GL  G+ Y F+++A++ 
Sbjct: 12740 WDRPDSDGGSPIIGYLIERKERNSLLWVKANDTLVRSTEYPCAGLVEGLEYSFRIYALNK 12799

Query: 983   GRESKPL--TAQQTTKL--DAPTNLQFVNETDSTVLVRWTPPR----AQITGYRLTVGLT 1034
                S P   T   T ++  D P   + ++ T STV + W  P+    ++I GY +     
Sbjct: 12800 AGSSPPSKPTEYVTARMPVDPPGKPEVIDVTKSTVSLIWARPKHDGGSKIIGYFVEACKL 12859

Query: 1035  RRGQPRQYNVGPSV---SKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSI 1091
                +  + N  P      +Y    L+  ++Y    +A      SP +           ++
Sbjct: 12860 PGDKWVRCNTAPHQIPQEEYTATGLEEKAQYQFRAIARTAVNISPPSEPSDPVTILAENV 12919

Query: 1092  PP----------YNTEVTETTIVITWT----PAPRIGFKLG---VRPSQGGEAPREVTSD 1134
             PP            T    T + +  T    P P + +K     ++P++G +   +   +
Sbjct: 12920 PPRIDLSVAMKSLLTVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQ--RN 12977

Query: 1135  SGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVS 1194
               ++ +  +       YTI        + A I  KV+    PP ++ +        + +S
Sbjct: 12978 LCTLELFSVNRKDSGDYTITAENSSGSKSATIKLKVLDKPGPPASVKINKMYSDRAM-LS 13036

Query: 1195  WE---RSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVK 1251
             WE        +IT Y +    T+      +   V    +SC+ + L  G EY   +    
Sbjct: 13037 WEPPLEDGGSEITNYIVDKRETSRPNWAQVSATVPI--TSCSVEKLIEGHEYQFRICAEN 13094

Query: 1252  DDKESVPI-SDTIIPAVP--------PPTDLRFTNIGPDTMRVTWAPPPS---IDLTNFL 1299
                   P+ ++  I   P        PP     +NI  D M V+W PP       +T +L
Sbjct: 13095 KYGVGDPVFTEPAIAKNPYDPPGRCDPPV---ISNITKDHMTVSWKPPADDGGSPITGYL 13151

Query: 1300  V--RYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTG 1357
             +  R +   N   V    I   +  +  T L  GTEY   V+++ +     P    +   
Sbjct: 13152 LEKRETQAVNWTKVNRKPII--ERTLKATGLQEGTEYEFRVTAINKAGPGKPSDASKAAY 13209

Query: 1358  LDSP-------TGIDFSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPREDRV 1406
                P             D T +S ++ W  P     + I GY +           R +  
Sbjct: 13210 ARDPQYPPGPPAFPKVYDTTRSSVSLSWGKPAYDGGSPIIGYLVEVKRADSDNWVRCNLP 13269

Query: 1407  PH-SRNSITLTNLTPGTEYVVSIVALNGREES-PLLIGQQSTVSDV--PRDLEVVAATPT 1462
              +  +    +T L   T+Y   + A+N    S P  +  +    D+  P + E+ A    
Sbjct: 13270 QNLQKTRFEVTGLMEDTQYQFRVYAVNKIGYSDPSDVPDKHYPKDILIPPEGELDADLRK 13329

Query: 1463  SLLISWDAPAVTVRYY---------RITYGETGGNSPVQEFTVPGSKSTATISGLKPGVD 1513
             +L++      VT+R Y         +IT+ +   N   +      S    T    +    
Sbjct: 13330 TLILR---AGVTMRLYVPVKGRPPPKITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNK 13386

Query: 1514  YTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLP----SSSPV 1569
             Y    Y +T           I +        P  + V ++  +S  V W P      SP+
Sbjct: 13387 YDAGKYILTLENSCGKKEYTIVVKVLDTPGPPVNVTVKEISKDSAYVTWEPPIIDGGSPI 13446

Query: 1570  TGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAV 1629
               Y V            T T    +T   +  L+    Y   V+A+N  G   P      
Sbjct: 13447 INYVVQKRDAERKS-WSTVTTECSKTSFRVANLEEGKSYFFRVFAENEYGIGDPGETRDA 13505

Query: 1630  TNIDRPKG----LAFTDVDVDSIKIAWESPQG----QVSRYRVTYSSPEDGIHELFPAPD 1681
                 +  G    L    V   S  I W+ P      ++  Y V + + E+    +  +  
Sbjct: 13506 VKASQTPGPVVDLKVRSVSKSSCSIGWKKPHSDGGSRIIGYVVDFLTEENKWQRVMKSLS 13565

Query: 1682  GEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQ 1741
              +    +L     G EYT  V A +++ E  P        + A  D     V    L  +
Sbjct: 13566 LQYSAKDLT---EGKEYTFRVSAENENGEGTP----SEITVVARDD-----VVAPDLDLK 13613

Query: 1742  WTPPNVQL----TGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKD 1797
               P    L    + +R+++  K K  P        D        L   T+  V   A+  
Sbjct: 13614 GLPDLCYLAKENSNFRLKIPIKGKPAPSVSWKKGEDP-------LATDTRVSVESSAVNT 13666

Query: 1798  TLTSRPAQ----GVVT-TLENVSPPRRARVT-----------------DATETTITISWR 1835
             TL     Q    G  T TL+NV+  +   ++                 + T   +T+ W 
Sbjct: 13667 TLIVYDCQKSDAGKYTITLKNVAGTKEGTISIKVVGKPGIPTGPIKFDEVTAEAMTLKWA 13726

Query: 1836  TKTET----ITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYL-----YTL 1886
                +     IT + ++   +     +         ++ +T L  G +Y   +     Y +
Sbjct: 13727 PPKDDGGSEITNYILEKRDSVNNKWVTCASAVQKTTFRVTRLHEGMEYTFRVSAENKYGV 13786

Query: 1887  NDNARSSPVVIDASTAI-DAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPG 1941
              +  +S P+V      + DAP     +    +S+ ++W  P+    + ITGY +++++  
Sbjct: 13787 GEGLKSEPIVARHPFDVPDAPPPPNIVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKERN 13846

Query: 1942  SPPREVVPRPRPGVTEATITGLEPGTEYTIYVIAL------KNNQKSEPLI--------G 1987
             S   +   +    + +  +TGL  G EY   V+A+      K +  SEP++        G
Sbjct: 13847 SLLWKRANKTPIRMRDFKVTGLTEGLEYEFRVMAINLAGVGKPSLPSEPVVALDPIDPPG 13906

Query: 1988  RKKTV-----QKTPFVTHPGYDTGN 2007
             + + +       T   T P YD G+
Sbjct: 13907 KPEVINITRNSVTLIWTEPKYDGGH 13931



 Score = 91.7 bits (226), Expect = 8e-18
 Identities = 294/1501 (19%), Positives = 530/1501 (35%), Gaps = 198/1501 (13%)

Query: 628   IQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISI 684
             + W  P     S I+ Y+L  R   +V   K    P    +    GL+ G  YE ++ +I
Sbjct: 13134 VSWKPPADDGGSPITGYLLEKRETQAVNWTKVNRKPIIERTLKATGLQEGTEYEFRVTAI 13193

Query: 685   QQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSW---- 740
              + G  + +              S         + P       V + T SS  +SW    
Sbjct: 13194 NKAGPGKPSD------------ASKAAYARDPQYPPGPPAFPKVYDTTRSSVSLSWGKPA 13241

Query: 741   VSASDTVSGFRVEYELSEEGDEPQYLDLPST--ATSVNIPDLLPGRKYIVNVYQISEDGE 798
                   + G+ VE + + + D     +LP     T   +  L+   +Y   VY +++ G 
Sbjct: 13242 YDGGSPIIGYLVEVKRA-DSDNWVRCNLPQNLQKTRFEVTGLMEDTQYQFRVYAVNKIG- 13299

Query: 799   QSLILSTSQTTAPD--------APPDPTVDQVDDTSIVVR---WSRPQAPITGYRIVYSP 847
                   +  +  PD         PP+  +D     ++++R     R   P+ G      P
Sbjct: 13300 -----YSDPSDVPDKHYPKDILIPPEGELDADLRKTLILRAGVTMRLYVPVKGRP---PP 13351

Query: 848   SVEGSSTELNLPETAN-SVTLSDLQPGV-----------QYNITIYAVEENQESTPVVIQ 895
              +  S   +NL +     +  +D    +           +Y +T+      +E T VV  
Sbjct: 13352 KITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKYILTLENSCGKKEYTIVVKV 13411

Query: 896   QETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPGEHG 951
              +T G P + TV         E++     + W PP     S +  Y V            
Sbjct: 13412 LDTPGPPVNVTVK--------EISKDSAYVTWEPPIIDGGSPIINYVVQKRDAERKSWST 13463

Query: 952   QRLPISRNTFAEVTGLSPGVTYYFKVFAVSH---GRESKPLTAQQTTKLDAP-TNLQFVN 1007
                  S+ +F  V  L  G +Y+F+VFA +    G   +   A + ++   P  +L+  +
Sbjct: 13464 VTTECSKTSF-RVANLEEGKSYFFRVFAENEYGIGDPGETRDAVKASQTPGPVVDLKVRS 13522

Query: 1008  ETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYT 1063
              + S+  + W  P     ++I GY +   LT   + ++     S+ +Y  ++L    EYT
Sbjct: 13523 VSKSSCSIGWKKPHSDGGSRIIGYVVDF-LTEENKWQRVMKSLSL-QYSAKDLTEGKEYT 13580

Query: 1064  VSLVAIKGNQE-SPKATGVFT---TLQPG---SSIPPYNTEVTETT-----IVITWTPAP 1111
               + A   N E +P    V      + P      +P       E +     I I   PAP
Sbjct: 13581 FRVSAENENGEGTPSEITVVARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPIKGKPAP 13640

Query: 1112  RIGFKLGVRP-SQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKV 1170
              + +K G  P +       E ++ + +++V          YTI +      ++  I  KV
Sbjct: 13641 SVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKEGTISIKV 13700

Query: 1171  VTPLSPPTNLHLEANPDTGVLTVSW---ERSTTPDITGYRITTTPTNGQQGNSLEEVVHA 1227
             V     PT            +T+ W   +     +IT Y +    +   +  +    V  
Sbjct: 13701 VGKPGIPTGPIKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDSVNNKWVTCASAV-- 13758

Query: 1228  DQSSCTFDNLSPGLEYNVSV-----YTVKDDKESVPI---SDTIIPAVPPPTDLRFTNIG 1279
              +++     L  G+EY   V     Y V +  +S PI       +P  PPP ++   ++ 
Sbjct: 13759 QKTTFRVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVPDAPPPPNI--VDVR 13816

Query: 1280  PDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVA-----ELSISPSDNAVVLTNLLPGTEY 1334
              D++ +TW  P     +     +   K    +      +  I   D  V  T L  G EY
Sbjct: 13817 HDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTPIRMRDFKV--TGLTEGLEY 13874

Query: 1335  VVSVSSVYEQHESTPLRGRQKT----GLDSPTGIDFSDITANSFTVHWIAPR----ATIT 1386
                V ++       P    +       +D P   +  +IT NS T+ W  P+      +T
Sbjct: 13875 EFRVMAINLAGVGKPSLPSEPVVALDPIDPPGKPEVINITRNSVTLIWTEPKYDGGHKLT 13934

Query: 1387  GYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN--GREESPLLIGQQ 1444
             GY +           + + V     + T+T+L  G +Y   I A N  G   +P     +
Sbjct: 13935 GYIVEKRDLPSKSWMKANHVNVPECAFTVTDLVEGGKYEFRIRAKNTAGAISAP----SE 13990

Query: 1445  STVSDVPRDLEVVAATPTSLLISWDAPAVTVR----------------YYRITYGETGGN 1488
             ST + + +D       PT +L       +T++                  + ++ + G +
Sbjct: 13991 STETIICKD---EYEAPTIVLDPTIKDGLTIKAGDTIVLNAISILGKPLPKSSWSKAGKD 14047

Query: 1489  SPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQM 1548
                 + T   S  T+++  +K         Y +T         + + +        P  +
Sbjct: 14048 IRPSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFGTKVEHVKVTVLDVPGPPGPV 14107

Query: 1549  QVTDVQDNSISVKWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQP 1604
             ++++V     ++ W P      SP+  Y +     +    T           +  + +Q 
Sbjct: 14108 EISNVSAEKATLTWTPPLEDGGSPIKSYILEKRETSRLLWTVVSEDIQSCRHVATKLIQG 14167

Query: 1605  TVEYVVSVYAQNPSGESQPLVQTAVTNIDR------PKGLAFTDVDVDSIKIAWESP--- 1655
               EY+  V A N  G+ +P+    V  +DR      P+    ++V  ++  ++W+ P   
Sbjct: 14168 N-EYIFRVSAVNHYGKGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSWKRPVDD 14226

Query: 1656  -QGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVA-----LHDDM 1709
                +++ Y V     +             +   ++ GL+ GS Y   V A     +    
Sbjct: 14227 GGSEITGYHVERREKKSLRWVRAIKTPVSDLRCKVTGLQEGSTYEFRVSAENRAGIGPPS 14286

Query: 1710  ESQPLIGTQSTAIP--APTDLKFTQVTPTSLSAQWTPPN----VQLTGYRVRVTPKEKTG 1763
             E+   +  +  A P   P++   T  T  S S  W  P+    +++TGY   V   +K G
Sbjct: 14287 EASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLAWGKPHYDGGLEITGY---VVEHQKVG 14343

Query: 1764  PMKEI----NLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRR 1819
                 I      A   +  VV  L    KY   + A+ D     PA  V+  +E V     
Sbjct: 14344 DEAWIKDTTGTALRITQFVVPDLQTKEKYNFRISAINDAGVGEPA--VIPDVEIVEREMA 14401

Query: 1820  ARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIK-------PDVRSYTITG 1872
                    E   T+  R          +   PA   T  +  I         +  S+T+  
Sbjct: 14402 PDFELDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKNRANIENTESFTLLI 14461

Query: 1873  LQPGTDYKI--YLYTLNDNARSSPVVIDASTAIDAPS---NLRFLATTPNSLLVSWQPP- 1926
             +     Y    ++ T+ + A      ++    +D P    NLR    T +S+ + W  P 
Sbjct: 14462 IPECNRYDTGKFVMTIENPAGKKSGFVNV-RVLDTPGPVLNLRPTDITKDSVTLHWDLPL 14520

Query: 1927  ---RARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSE 1983
                 +RIT YI++ ++  +         +       +TGL  G EY   V+A       E
Sbjct: 14521 IDGGSRITNYIVE-KREATRKSYSTATTKCHKCTYKVTGLSEGCEYFFRVMAENEYGIGE 14579

Query: 1984  P 1984
             P
Sbjct: 14580 P 14580



 Score = 90.9 bits (224), Expect = 1e-17
 Identities = 273/1318 (20%), Positives = 459/1318 (34%), Gaps = 189/1318 (14%)

Query: 771   TATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPP---DPTVDQVDDTSI 827
             ++TS  + DL     +   V   +E G      +T    A + P    D ++     TS+
Sbjct: 21048 SSTSFKLIDLSEKTPFFFRVLAENEIGIGEPCETTEPVKAAEVPAPIRDLSMKDSTKTSV 21107

Query: 828   VVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAV 883
             ++ W++P     + IT Y +      E + +   + +T   + +S L+        ++A 
Sbjct: 21108 ILSWTKPDFDGGSVITEYVVERKGKGEQTWSHAGISKTCE-IEVSQLKEQSVLEFRVFAK 21166

Query: 884   EENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIP 943
              E   S PV I   T      + + +P ++   ++   +VT+           Y+    P
Sbjct: 21167 NEKGLSDPVTIGPITV----KELIITP-EVDLSDIPGAQVTVRIGHNVHLELPYKGKPKP 21221

Query: 944   VNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTN- 1002
                  + G  LP+  + F   +     +T   K     HG +   +      ++  P   
Sbjct: 21222 SISWLKDG--LPLKESEFVRFSKTENKITLSIKNAKKEHGGKYTVILDNAVCRIAVPITV 21279

Query: 1003  ------------LQFVNETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGP 1046
                         ++F      +V++ W  P      +IT Y +    T +   +      
Sbjct: 21280 ITLGPPSKPKGPIRFDEIKADSVILSWDVPEDNGGGEITCYSIEKRETSQTNWKMVCSSV 21339

Query: 1047  SVSKYPLRNLQPASEYTVSLVAI-KGNQESPKATGVFTTLQ----PGSSIPPYNTEVTET 1101
             + + + + NL   +EY   + A  +     P  + +         PG    P    VT  
Sbjct: 21340 ARTTFKVPNLVKDAEYQFRVRAENRYGVSQPLVSSIIVAKHQFRIPGPPGKPVIYNVTSD 21399

Query: 1102  TIVITWTP------APRIGFKLGVRPSQGGEAPREVTSD-SG-SIVVSGLTPGVEYVYTI 1153
              + +TW        +   GF +  +        +  TS  SG     +GL  G++Y + +
Sbjct: 21400 GMSLTWDAPVYDGGSEVTGFHVEKKERNSILWQKVNTSPISGREYRATGLVEGLDYQFRV 21459

Query: 1154  QVLRDG---QERDAPIVNKVVTPLSPP-TNLHLEANPDTGVLTVSWE---RSTTPDITGY 1206
                         D       V+P+ PP T  +++   +T  +T+ W    R     I GY
Sbjct: 21460 YAENSAGLSSPSDPSKFTLAVSPVDPPGTPDYIDVTRET--ITLKWNPPLRDGGSKIVGY 21517

Query: 1207  RITTTPTNGQQGNSL-EEVVHADQSSC--TFDNLSPGLEYNV------SVYTVKDDKESV 1257
              I       +QGN         D S C  T   LSPG  Y        +V T+    +S 
Sbjct: 21518 SIEK-----RQGNERWVRCNFTDVSECQYTVTGLSPGDRYEFRIIARNAVGTISPPSQSS 21572

Query: 1258  PISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNE---EDVAEL 1314
              I  T    VPP         GP+                 LV+  PV      +D  E+
Sbjct: 21573 GIIMTRDENVPP-----IVEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVTWFKDGVEI 21627

Query: 1315  SISPSDNAVVLTNLLPGTEYVV--------SVSSVYEQHESTPLRGRQKTGLDSPTG--- 1363
                 +   + +T++L  T   V         V +V  ++ S   +   K  +    G   
Sbjct: 21628 EKRMN---MEITDVLGSTSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQDTPGKVV 21684

Query: 1364  --IDFSDITANSFTVHWIAPR----ATITGYRI-RHHPEHFSGRPREDRVPHSRNSITLT 1416
               I F++IT    T+ W AP     A IT Y I +      +    ED+      S T  
Sbjct: 21685 GPIRFTNITGEKMTLWWDAPLNDGCAPITHYIIEKRETSRLAWALIEDKC--EAQSYTAI 21742

Query: 1417  NLTPGTEYVVSIVALN----GR--EESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDA 1470
              L  G EY   + A+N    GR  +  P++   Q TV D P   E    T  S+ ++W  
Sbjct: 21743 KLINGNEYQFRVSAVNKFGVGRPLDSDPVVAQIQYTVPDAPGIPEPSNITGNSITLTWAR 21802

Query: 1471  PAVTVRYYRITYGETGGNSPVQEFTV-----------------PGSKSTATISGLKPGVD 1513
             P            E+ G S +Q++ +                 P S++   ++GL  G +
Sbjct: 21803 P------------ESDGGSEIQQYILERREKKSTRWVKVISKRPISETRFKVTGLTEGNE 21850

Query: 1514  YTITVYAVTGRGDSPASSKPISINYRTEIDKPSQ---MQVTDVQDNSISVKW----LPSS 1566
             Y   V A    G  PAS     I  R  ++ P     ++VTD    ++S++W        
Sbjct: 21851 YEFHVMAENAAGVGPASGISRLIKCREPVNPPGPPTVVKVTDTSKTTVSLEWSKPVFDGG 21910

Query: 1567  SPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQ 1626
               + GY +     +     K       +T  T+  LQ   EY   V A N +G+      
Sbjct: 21911 MEIIGYIIEMCKADLGDWHKVNAEACVKTRYTVTDLQAGEEYKFRVSAINGAGKGDSCEV 21970

Query: 1627  TA-VTNIDRPKGLAFTDVDVDS-IKIAWESPQGQVSRYRVTY----------SSPEDGIH 1674
             T  +  +DR   L   ++D+D+  K       G   R  + Y          S P+  + 
Sbjct: 21971 TGTIKAVDR---LTAPELDIDANFKQTHVVRAGASIRLFIAYQGRPTPTAVWSKPDSNLS 22027

Query: 1675  ---ELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFT 1731
                ++         T E        +YT++V            +    T  P P  + F 
Sbjct: 22028 LRADIHTTDSFSTLTVENCNRNDAGKYTLTVENNSGSKSITFTVKVLDTPGP-PGPITFK 22086

Query: 1732  QVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKE----INLAPDSSSVVVSGLMVATK 1787
              VT  S +  W  P +   G R+     EK    +     I+         V+ L     
Sbjct: 22087 DVTRGSATLMWDAPLLD-GGARIHHYVVEKREASRRSWQVISEKCTRQIFKVNDLAEGVP 22145

Query: 1788  YEVSVYALKDTLTSRPAQ--GVVTTLENVSPPRRARVTDATETTITISW----RTKTETI 1841
             Y   V A+ +     P +    +   E  +PPRR  V D ++++  ++W          I
Sbjct: 22146 YYFRVSAVNEYGVGEPYEMPEPIVATEQPAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRI 22205

Query: 1842  TGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDAST 1901
             TG+ ++         ++      + ++T+  L   T+Y+  +   ND   S P    +S 
Sbjct: 22206 TGYLLEMRQKGSDFWVEAGHTKQL-TFTVERLVEKTEYEFRVKAKNDAGYSEPREAFSSV 22264

Query: 1902  AIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVP---RPRPGVT 1956
              I  P         P + L         IT  +I   K GSP    VP   RP P VT
Sbjct: 22265 IIKEPQ------IEPTADLTG-------ITNQLITC-KAGSPFTIDVPISGRPAPKVT 22308



 Score = 89.7 bits (221), Expect = 3e-17
 Identities = 260/1286 (20%), Positives = 475/1286 (36%), Gaps = 231/1286 (17%)

Query: 780  LLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPIT 839
            ++P ++Y++ V  ++  G       +    A D    PT+D      IV+   +   P+ 
Sbjct: 7978 VVPDKEYVLRVRAVNAIGVSEPSEISENVVAKDPDCKPTIDLETHDIIVIEGEKLSIPVP 8037

Query: 840  GYRIVYSPSV----EGSSTELNLPETANSVTLS---DLQPGVQYNITIYAV--EENQEST 890
             +R V  P+V    +G   + +   T  +  +S   ++   V+ +  IY +  E    S 
Sbjct: 8038 -FRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSA 8096

Query: 891  PVVIQQETTGTPRSDTVPSP-RDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGE 949
               I  +  G      +P P +D++  ++T     + W PPE    G    +  V    E
Sbjct: 8097 TASINVKVIG------LPGPCKDIKASDITKSSCKLTWEPPE--FDGGTPILHYVLERRE 8148

Query: 950  HGQR--LPI--SRNTFA-EVTGLSPGVTYYFKVFAVSH--GRE----SKPLTAQQTTKL- 997
             G+R  +P+    N  +  V  L P   Y+F+V AV+   G E      P+ AQ   +  
Sbjct: 8149 AGRRTYIPVMSGENKLSWTVKDLIPNGEYFFRVKAVNKVGGGEYIELKNPVIAQDPKQPP 8208

Query: 998  DAPTNLQFVNETDSTVLVRWTPPR----AQITGY---RLTVGLTRRGQPRQYNVGPSVSK 1050
            D P +++  N T   + + W PP     ++I GY   ++  G  R  +  ++ V   +  
Sbjct: 8209 DPPVDVEVHNPTAEAMTITWKPPLYDGGSKIMGYIIEKIAKGEERWKRCNEHLV--PILT 8266

Query: 1051 YPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPA 1110
            Y  + L+   EY   + A         A G+    +P  + PP        T  +    A
Sbjct: 8267 YTAKGLEEGKEYQFRVRA-------ENAAGIS---EPSRATPP--------TKAVDPIDA 8308

Query: 1111 PRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVL--RDGQERDAPIVN 1168
            P++  +  +   +G E   +  S SGS       P + ++    V+   + ++R AP+V 
Sbjct: 8309 PKVILRTSLEVKRGDEIALDA-SISGSPY-----PTITWIKDENVIVPEEIKKRAAPLVR 8362

Query: 1169 KVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHAD 1228
            +    +       L   P T  L++                    N ++G S   V    
Sbjct: 8363 RRKGEVQEEEPFVL---PLTQRLSID-------------------NSKKGESQLRVR--- 8397

Query: 1229 QSSCTFDNLSPGLEYNVSVYTVKDDK--ESVPISDTIIPAVPPPTDLRFTNIGPDTMRVT 1286
                  D+L P  ++ + +  V++D      P + +++    PP +  F +I   ++   
Sbjct: 8398 ------DSLRP--DHGLYMIKVENDHGIAKAPCTVSVLDTPGPPINFVFEDIRKTSVLCK 8449

Query: 1287 WAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHE 1346
            W PP   D  + ++ Y+  K ++        P    +V+T+ L   +Y  SV+ + E  E
Sbjct: 8450 WEPPLD-DGGSEIINYTLEKKDKT------KPDSEWIVVTSTLRHCKY--SVTKLIEGKE 8500

Query: 1347 ------------------STPLRGRQKTGL-DSPTGIDFSDITANSFTVHWIAPR---AT 1384
                              S PL  +   G  D+P      D+T+NS  V W  P+   + 
Sbjct: 8501 YLFRVRAENRFGPGPPCVSKPLVAKDPFGPPDAPDKPIVEDVTSNSMLVKWNEPKDNGSP 8560

Query: 1385 ITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN----GREESPLL 1440
            I GY +     + +   R ++   +     +  L  G  YV  + A N    G+   P  
Sbjct: 8561 ILGYWLEKREVNSTHWSRVNKSLLNALKANVDGLLEGLTYVFRVCAENAAGPGKFSPP-- 8618

Query: 1441 IGQQSTVSD--------VPRDLEVVAATPTSLLISWDAPAVT----VRYYRITYGETGGN 1488
                 T  D        +PR   V   + T++ + W+ PA      +  Y +     G N
Sbjct: 8619 -SDPKTAHDPISPPGPPIPR---VTDTSSTTIELEWEPPAFNGGGEIVGYFVDKQLVGTN 8674

Query: 1489 SPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDS-PASSKPISINYRTEIDKPSQ 1547
               +           T+  ++ G DY + V AV   G+  P  ++P+++    E  +P  
Sbjct: 8675 EWSRCTEKMIKVRQYTVKEIREGADYKLRVSAVNAAGEGPPGETQPVTV---AEPQEPPA 8731

Query: 1548 MQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTK--TKTAGP-DQTEMTIEGLQP 1604
            +++       +SVK           R+       P PTK  TK  G  D+  + I+ +  
Sbjct: 8732 VEL------DVSVKGGIQIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKDRVVIDNVGT 8785

Query: 1605 TVEYVVS-----------VYAQNPSGESQPLVQTAVTNIDRP-KGLAFTDVDVDSIKIAW 1652
              E ++            + A N  G      +  V ++  P   L     +     + W
Sbjct: 8786 KSELIIKDALRKDHGRYVITATNSCGSKFAAARVEVFDVPGPVLDLKPVVTNRKMCLLNW 8845

Query: 1653 ESPQ----GQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALH-- 1706
              P+     +++ + +     +  +H      + E    ++ GL  G EY   V+A +  
Sbjct: 8846 SDPEDDGGSEITGFIIERKDAK--MHTWRQPIETERSKCDITGLLEGQEYKFRVIAKNKF 8903

Query: 1707 ---DDMESQPLIGTQSTAIP-APTDLKFTQVTPTSLSAQWTPPNVQ----LTGYRVRVTP 1758
                 +E  P++       P +P  L +T+ T ++++  W  P       + GY +    
Sbjct: 8904 GCGPPVEIGPILAVDPLGPPTSPERLTYTERTKSTITLDWKEPRSNGGSPIQGYIIEKRR 8963

Query: 1759 KEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPA--QGVVTTLENVSP 1816
             +K    +       ++S +V  L     YE  V A+ +   S P+    VV   + V P
Sbjct: 8964 HDKPDFERVNKRLCPTTSFLVENLDEHQMYEFRVKAVNEIGESEPSLPLNVVIQDDEVPP 9023

Query: 1817 PRRARVTDATETTIT-------------------ISWRTKTETITGFQVDAVPANGQTPI 1857
              + R++   +T                      I W +K ET+     DA+    +   
Sbjct: 9024 TIKLRLSVRGDTIKVKAGEPVHIPADVTGLPMPKIEW-SKNETVIEKPTDALQITKEEVS 9082

Query: 1858 QRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAI-DAPSNLRFLATT- 1915
            +   K ++          GT      YT+  + R   V  +    + D PS  R LA T 
Sbjct: 9083 RSEAKTELSIPKAVREDKGT------YTVTASNRLGSVFRNVHVEVYDRPSPPRNLAVTD 9136

Query: 1916 --PNSLLVSWQPP----RARITGYII 1935
                S  ++W  P     + IT Y+I
Sbjct: 9137 IKAESCYLTWDAPLDNGGSEITHYVI 9162



 Score = 89.7 bits (221), Expect = 3e-17
 Identities = 320/1572 (20%), Positives = 568/1572 (36%), Gaps = 254/1572 (16%)

Query: 611   PVEVFITETPSQP----------NSHPIQWNAPQP---SHISKYILRWRPKNSVGRWKEA 657
             P  +  TE P+ P          +S  + W  P     S I+ Y+L  R K S   W EA
Sbjct: 22165 PEPIVATEQPAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGS-DFWVEA 22223

Query: 658   TIPGHLN--SYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNT--VTG 713
                GH    ++T++ L     YE ++ +    G+ E  R  F++     P    T  +TG
Sbjct: 22224 ---GHTKQLTFTVERLVEKTEYEFRVKAKNDAGYSE-PREAFSSVIIKEPQIEPTADLTG 22279

Query: 714   ETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTAT 773
              T       A S    ++  S      V+       +++E    +E D    +      T
Sbjct: 22280 ITNQLITCKAGSPFTIDVPISGRPAPKVT-------WKLEEMRLKETDRVS-ITTTKDRT 22331

Query: 774   SVNIPDLLPGR--KYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPT-VDQVDDTSIVVR 830
             ++ + D + G   +Y + +   +  G ++  ++      P     P  V  V   S V+ 
Sbjct: 22332 TLTVKDSMRGDSGRYFLTLENTA--GVKTFSVTVVVIGRPGPVTGPIEVSSVSAESCVLS 22389

Query: 831   WSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITI-----Y 881
             W  P+      IT Y +    S   +   +N       + ++ L   ++Y+  +     +
Sbjct: 22390 WGEPKDGGGTEITNYIVEKRESGTTAWQLVNSSVKRTQIKVTHLTKYMEYSFRVSSENRF 22449

Query: 882   AVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGY 937
              V +  ES P++ +      P + T P     +   V+   ++I W  P     S + GY
Sbjct: 22450 GVSKPLESAPIIAEHPFV-PPSAPTRP-----EVYHVSANAMSIRWEEPYHDGGSKIIGY 22503

Query: 938   RVDVIPVN-LPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFA-----VSHGRE-SKPLT 990
              V+    N +      ++P     + +VTGL  G+ Y F+ +A     VS   E S+P+ 
Sbjct: 22504 WVEKKERNTILWVKENKVPCLECNY-KVTGLVEGLEYQFRTYALNAAGVSKASEASRPIM 22562

Query: 991   AQQTTKLDAPTNLQFVNETDSTVLVRWTPPR----AQITGYRL----------------- 1029
             AQ    +DAP   +  + T STV + W+ P     +++ GY +                 
Sbjct: 22563 AQ--NPVDAPGRPEVTDVTRSTVSLIWSAPAYDGGSKVVGYIIERKPVSEVGDGRWLKCN 22620

Query: 1030  ---------TVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKAT- 1079
                      TV     G   ++ V   ++K     +   SE T   V  +     PKA  
Sbjct: 22621 YTIVSDNFFTVTALSEGDTYEFRV---LAKNAAGVISKGSEST-GPVTCRDEYAPPKAEL 22676

Query: 1080  -----GVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGE-APREVTS 1133
                  G   T++ GS +             +   P P+I +  G +     E    + T 
Sbjct: 22677 DARLHGDLVTIRAGSDL--------VLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTG 22728

Query: 1134  DSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTV 1193
                + V+          YT+ V      +   ++ KV+    P   L + +       T+
Sbjct: 22729 KRATAVIKFCDRSDSGKYTLTVKNASGTKAVSVMVKVLDSPGPCGKLTV-SRVTQEKCTL 22787

Query: 1194  SWERSTTPDITGYRITTTPTNGQQGNSLEEVV---HADQSSCTFDNLSPGLEYNVSVYTV 1250
             +W  S   +  G  IT      ++ + L  V+        S     L    EY   V  V
Sbjct: 22788 AW--SLPQEDGGAEITHYIVERRETSRLNWVIVEGECPTLSYVVTRLIKNNEYIFRVRAV 22845

Query: 1251  KDDKESVPISDTIIPA-----VP-PPTDLRFTNIGPDTMRVTWAPPPS---IDLTNFLV- 1300
                   VP+    I A     +P PP        G + + + W  P S    +++N+LV 
Sbjct: 22846 NKYGPGVPVESEPIVARNSFTIPSPPGIPEEVGTGKEHIIIQWTKPESDGGNEISNYLVD 22905

Query: 1301  -------RYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGR 1353
                    R++ V  +  V        D  + +T+L+ G +Y   V++V     S P    
Sbjct: 22906 KREKKSLRWTRVNKDYVV-------YDTRLKVTSLMEGCDYQFRVTAVNAAGNSEPSEAS 22958

Query: 1354  QKTGL-------DSPTGIDFSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPR 1402
                           P+     D T +S ++ W  P       I GY +    +      R
Sbjct: 22959 NFISCREPSYTPGPPSAPRVVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDTDQWYR 23018

Query: 1403  EDRVPHSRNS-ITLTNLTPGTEYVVSIVALN--GREESPLLIGQQSTVS--DVPRDLEVV 1457
                    RN+  T+ +L  G +Y   + A+N  G  E    I +   V   ++P DLE+ 
Sbjct: 23019 VHTNATIRNTEFTVPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEIP-DLELA 23077

Query: 1458  AATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTIT 1517
                  ++ I   A        R+    +G   PV  ++  G    A+ + +     Y++ 
Sbjct: 23078 DDLKKTVTIRAGAS------LRLMVSVSGRPPPVITWSKQGI-DLASRAIIDTTESYSLL 23130

Query: 1518  V-----------YAVTGRGDSPASSKPISIN-YRTEIDKPSQMQVTDVQDNSISVKW--- 1562
             +           Y +     S   S  + +  Y T    PS ++V +V  +S+++ W   
Sbjct: 23131 IVDKVNRYDAGKYTIEAENQSGKKSATVLVKVYDTPGPCPS-VKVKEVSRDSVTITWEIP 23189

Query: 1563  -LPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGES 1621
              +   +PV  Y +    +      KT T    +T   I GL     Y   V  +N  G  
Sbjct: 23190 TIDGGAPVNNY-IVEKREAAMRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYGIG 23248

Query: 1622  QPLVQTAVTNIDR----PKGLAFTDVDVDSIKIAWESP----QGQVSRY--RVTYSSPED 1671
             +P   +    +      P  L   DV   ++ +AWE P      +++ Y      +  E 
Sbjct: 23249 EPCETSDAVLVSEVPLVPAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGTER 23308

Query: 1672  GIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFT 1731
              +  +   P   E T  +  L  G +Y   + A ++   S+P    ++       DL+  
Sbjct: 23309 WMKVVTLKPTVLEHT--VTSLNEGEQYLFRIRAQNEKGVSEP---RETVTAVTVQDLR-- 23361

Query: 1732  QVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSG--------LM 1783
              V PT   +      + +   R    P E   P+      P ++S   +G        + 
Sbjct: 23362 -VLPTIDLSTMPQKTIHVPAGR----PVELVIPI--AGRPPPAASWFFAGSKLRESERVT 23414

Query: 1784  VATKYEVSVYALKDTLTSRPAQGVVTTLENVS-----------------PPRRARVTDAT 1826
             V T  +V+   +++T T R        L+NV+                 P    ++ +  
Sbjct: 23415 VETHTKVAKLTIRET-TIRDTGEYTLELKNVTGTTSETIKVIILDKPGPPTGPIKIDEID 23473

Query: 1827  ETTITISWRTKT----ETITGFQVDAVPAN--GQTPIQRTIKPDVRSYTITGLQPGTDYK 1880
              T+ITISW          ++G+ V+   A+  G  P+  ++     ++  T L  G +Y 
Sbjct: 23474 ATSITISWEPPELDGGAPLSGYVVEQRDAHRPGWLPVSESVTRS--TFKFTRLTEGNEYV 23531

Query: 1881  IYLYTLNDNARSSPV---VIDASTAI---DAPSNLRFLATTPNSLLVSWQPPR----ARI 1930
               +   N     S +   VI+  ++I     P  L+    + + + ++W PP     +++
Sbjct: 23532 FRVAATNRFGIGSYLQSEVIECRSSIRIPGPPETLQIFDVSRDGMTLTWYPPEDDGGSQV 23591

Query: 1931  TGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKK 1990
             TGYI++ ++  +     V +    +T    TGL  G EY   V A+      +P    K 
Sbjct: 23592 TGYIVERKEVRADRWVRVNKVPVTMTRYRSTGLTEGLEYEHRVTAINARGSGKPSRPSKP 23651

Query: 1991  TVQKTPFVTHPG 2002
              V   P +  PG
Sbjct: 23652 IVAMDP-IAPPG 23662



 Score = 88.2 bits (217), Expect = 9e-17
 Identities = 339/1547 (21%), Positives = 534/1547 (34%), Gaps = 251/1547 (16%)

Query: 628   IQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISI 684
             + W +P+    S I+ Y++  R  +    W   T      + T++GL  G  Y  ++ + 
Sbjct: 10263 LTWFSPEDDGGSPITNYVIEKRESDRRA-WTPVTYTVTRQNATVQGLIQGKAYFFRIAAE 10321

Query: 685   QQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSAS 744
                G        F  TS +  +        T P  P       V E+T ++  ++W    
Sbjct: 10322 NSIGMGP-----FVETSEALVIREPI----TVPERP---EDLEVKEVTKNTVTLTWNPPK 10369

Query: 745   DTVSGFRVEYELSEE--GDEPQYLDLPSTATS--VNIPDLLPGRKYIVNVYQISEDGEQS 800
                    + Y L     G E  +        S    +  L  G  Y   V  ++  G+  
Sbjct: 10370 YDGGSEIINYVLESRLIGTEKFHKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGK 10429

Query: 801   LILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPE 860
                 T   T  D    PT+       + +R     A    Y     P V     E ++ E
Sbjct: 10430 PSFCTKPITCKDELAPPTLHLDFRDKLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLE 10489

Query: 861   TANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQET---TGTPRSDTVPSPRD----L 913
               +  T     P       I A   +     VV++  T    G  + + V  P      +
Sbjct: 10490 --DDRTHIKTTPATLALEKIKAKRSDSGKYCVVVENSTGSRKGFCQVNVVDRPGPPVGPV 10547

Query: 914   QFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPGEHGQRLPI---SRNTFAEVTG 966
              F EVT   + I W PP     S +T Y ++   V         +P+   S  T  +V+ 
Sbjct: 10548 SFDEVTKDYMVISWKPPLDDGGSKITNYIIEKKEVG----KDVWMPVTSASAKTTCKVSK 10603

Query: 967   LSPGVTYYFKVFAVSHGRESKPLTAQQTTKLD------APTNLQFVNETDSTVLVRWTPP 1020
             L  G  Y F++ A +    S PL +      D      AP        T  + LV W  P
Sbjct: 10604 LLEGKDYIFRIHAENLYGISDPLVSDSMKAKDRFRVPDAPDQPIVTEVTKDSALVTWNKP 10663

Query: 1021  R---AQITGYRLTVGLTRRGQPRQYNVGP--SVSKYPLRNLQPASEYTVSLVA---IKGN 1072
                   IT Y L    T   +  +    P    +K+ + +L    +Y   + A   I   
Sbjct: 10664 HDGGKPITNYILEKRETMSKRWARVTKDPIHPYTKFRVPDLLEGCQYEFRVSAENEIGIG 10723

Query: 1073  QESPKATGVFTTLQPGSSIPPYNTEVTETT---IVITWTPAPR-------IGFKLGVRPS 1122
               SP +  VF         PP N E  +TT   + +TW P PR       +G+ +  +  
Sbjct: 10724 DPSPPSKPVFAKDPIAKPSPPVNPEAIDTTCNSVDLTWQP-PRHDGGSKILGYIVEYQ-K 10781

Query: 1123  QGGEAPREVTSDSGSIV-----VSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTP---L 1174
              G E  R       S       V+GL  G  Y + +  +    E D   V + V     L
Sbjct: 10782 VGDEEWRRANHTPESCPETKYKVTGLRDGQTYKFRVLAVNAAGESDPAHVPEPVLVKDRL 10841

Query: 1175  SPPTNLHLEANP---------DTGVLT----------VSWERSTTPDITGYRITTTPTNG 1215
              PP  L L+AN          DT  L+          V+W++      T  RI  TP   
Sbjct: 10842 EPP-ELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARIDVTPVGS 10900

Query: 1216  QQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRF 1275
             +    +    H D    +    +P     VSV  +  DK              PP DL  
Sbjct: 10901 KL--EIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDKPG------------PPRDLEV 10946

Query: 1276  TNIGPDTMRVTWAPPPSID---LTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGT 1332
             + I  D+  +TW  P       +TN++V    V + +  + LS +    +    +L  G 
Sbjct: 10947 SEIRKDSCYLTWKEPLDDGGSVITNYVVERRDVASAQ-WSPLSATSKKKSHFAKHLNEGN 11005

Query: 1333  EYVVSVSSVYEQHESTPLRGRQKT--GLDS------PTGIDFSDITANSFTVHWIAPR-- 1382
             +Y+  V++   Q+   P     K    LD       P  +   D+     ++ W  P   
Sbjct: 11006 QYLFRVAAE-NQYGRGPFVETPKPIKALDPLHPPGPPKDLHHVDVDKTEVSLVWNKPDRD 11064

Query: 1383  --ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN----GREE 1436
               + ITGY + +  E      +   V +      +T L  G  Y   + A N    G  +
Sbjct: 11065 GGSPITGYLVEYQEEGTQDWIKFKTVTNLE--CVVTGLQQGKTYRFRVKAENIVGLGLPD 11122

Query: 1437  SPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTV 1496
             + + I  Q  +  VP  +E+       L++       TVR+  I  G      P  ++T 
Sbjct: 11123 TTIPIECQEKL--VPPSVELDVKLIEGLVVK---AGTTVRFPAIIRGVP---VPTAKWTT 11174

Query: 1497  PGSK---------------STATISGL--KPGVDYTITVYAVTGRGDSPASSKPISINYR 1539
              GS+               S  TI     +   +Y ITV        + A SK ++++  
Sbjct: 11175 DGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEYQITV-------SNAAGSKTVAVHL- 11226

Query: 1540  TEIDKPSQ----MQVTDVQDNSISVKWLP----SSSPVTGYRVTT--TPKNGPGPTKTKT 1589
             T +D P      + + DV    +++ W P      SPV  Y V    T K+  G     +
Sbjct: 11227 TVLDVPGPPTGPINILDVTPEHMTISWQPPKDDGGSPVINYIVEKQDTRKDTWGVV---S 11283

Query: 1590  AGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDR------PKGLAFTDV 1643
             +G  +T++ I  LQ   EYV  V A+N  G   PL  T      +      P     TD+
Sbjct: 11284 SGSSKTKLKIPHLQKGCEYVFRVRAENKIGVGPPLDSTPTVAKHKFSPPSPPGKPVVTDI 11343

Query: 1644  DVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQ----GLRPGSEYT 1699
               ++  ++W  P+         Y      +   +   + +   A+L+    GL  G+ Y 
Sbjct: 11344 TENAATVSWTLPKSDGGSPITGYYMERREVTGKWVRVN-KTPIADLKFRVTGLYEGNTYE 11402

Query: 1700  VSVVALH------DDMESQPLIGTQSTAIPA-PTDLKFTQVTPTSLSAQWTPP----NVQ 1748
               V A +          S P+   +    P  P + K    +  +    WT P       
Sbjct: 11403 FRVFAENLAGLSKPSPSSDPIKACRPIKPPGPPINPKLKDKSRETADLVWTKPLSDGGSP 11462

Query: 1749  LTGYRVRVTPKEKTGPMKEINLAP--DSSSVVVSGLMVATKYEVSVYALKDTLTSRP--- 1803
             + GY V    K  T     IN        +  V GL+   +Y   + A        P   
Sbjct: 11463 ILGYVVE-CQKPGTAQWNRINKDELIRQCAFRVPGLIEGNEYRFRIKAANIVGEGEPREL 11521

Query: 1804  AQGVVTTLENVSPPR-------RARVTDATETTITISWRTK-------TETITG------ 1843
             A+ V+   + + PP        R  +T     TI I  R K       T T  G      
Sbjct: 11522 AESVIAK-DILHPPEVELDVTCRDVITVRVGQTIRILARVKGRPEPDITWTKEGKVLVRE 11580

Query: 1844  FQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAI 1903
              +VD +    +  +Q  IK  VR+           Y I     + +A+ S +V      +
Sbjct: 11581 KRVDLIQDLPRVELQ--IKEAVRA-------DHGKYIISAKNSSGHAQGSAIV----NVL 11627

Query: 1904  DAP---SNLRFLATTPNSLLVSWQPP----RARITGYIIKYEKPGSPPREVVPRPRPGVT 1956
             D P    NL+    T  +  +SW+ P     + IT +I++Y KP      +V      VT
Sbjct: 11628 DRPGPCQNLKVTNVTKENCTISWENPLDNGGSEITNFIVEYRKPNQKGWSIV---ASDVT 11684

Query: 1957  EATI-TGLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQKTPFVTHPG 2002
             +  I   L    EY   V A +N     P I  K  +     +  PG
Sbjct: 11685 KRLIKANLLANNEYYFRVCA-ENKVGVGPTIETKTPILAINPIDRPG 11730



 Score = 88.2 bits (217), Expect = 9e-17
 Identities = 260/1214 (21%), Positives = 438/1214 (36%), Gaps = 158/1214 (13%)

Query: 908   PSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPIS------RNTF 961
             P    L   EVT  K  + W PP     G ++D   V        RL  +      + T 
Sbjct: 15185 PPEGPLAVTEVTSEKCVLSWFPPLDD-GGAKIDHYIVQ--KRETSRLAWTNVASEVQVTK 15241

Query: 962   AEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKL------DAPTNLQFVNETDSTVLV 1015
              +VT L  G  Y F+V AV+     +PL ++    +      D P N +    T  +++V
Sbjct: 15242 LKVTKLLKGNEYIFRVMAVNKYGVGEPLESEPVLAVNPYGPPDPPKNPEVTTITKDSMVV 15301

Query: 1016  RWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVS-----KYPLRNLQPASEYTVSLVAIK 1070
              W  P +      +   + RR +  Q  +  +       +Y +  L    EY   ++A  
Sbjct: 15302 CWGHPDSDGGSEIINYIVERRDKAGQRWIKCNKKTLTDLRYKVSGLTEGHEYEFRIMAEN 15361

Query: 1071  -GNQESPKATGVF-----TTLQPGSSIPPYNTEVTET---TIVITWTP------APRIGF 1115
                  +P  T  F     T  +PG   PP N  V +T   +I I W        +   G+
Sbjct: 15362 AAGISAPSPTSPFYKACDTVFKPG---PPGNPRVLDTSRSSISIAWNKPIYDGGSEITGY 15418

Query: 1116  KLGVRPSQGGEAPREVTSDSG----SIVVSGLTPGVEYVYTIQVLRD---GQERDAPIVN 1168
              + +   +  E  + VT  +G    S  ++GLT   EY   I  +     G+    P   
Sbjct: 15419 MVEIALPEEDEW-QIVTPPAGLKATSYTITGLTENQEYKIRIYAMNSEGLGEPALVPGTP 15477

Query: 1169  KVVTPLSPP-TNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHA 1227
             K    + PP   L  +      +      R   P I G            G SL++    
Sbjct: 15478 KAEDRMLPPEIELDADLRKVVTIRACCTLRLFVP-IKGRPAPEVKWARDHGESLDKASIE 15536

Query: 1228  DQSSCTFDNLSPGLEYNVSVY--TVKDD--KESVPISDTIIPAVPPPTDLRFTNIGPDTM 1283
               SS T   +     ++   Y  TV++    +S  ++  ++    PP DL+   +   ++
Sbjct: 15537 STSSYTLLIVGNVNRFDSGKYILTVENSSGSKSAFVNVRVLDTPGPPQDLKVKEVTKTSV 15596

Query: 1284  RVTWAPPPSIDLTNFLVRYSPVKNE---EDVAELSISPSDNAVVLTNLLPGTEYVVSVSS 1340
              +TW  PP +D  + +  Y   K E   +  + ++ +    +  +  L  G  Y   V +
Sbjct: 15597 TLTW-DPPLLDGGSKIKNYIVEKRESTRKAYSTVATNCHKTSWKVDQLQEGCSYYFRVLA 15655

Query: 1341  VYEQHESTPLRGRQKTGLDS----PTGIDFSDITANSFTVHWIAPR----ATITGYRIRH 1392
               E     P    +          P  I   D+T NS ++ W  P     + I GY +  
Sbjct: 15656 ENEYGIGLPAETAESVKASERPLPPGKITLMDVTRNSVSLSWEKPEHDGGSRILGYIVEM 15715

Query: 1393  HPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPR 1452
               +          V       T+T L  G EY   + A N   E  +   +Q +V  + +
Sbjct: 15716 QTKGSDKWATCATV--KVTEATITGLIQGEEYSFRVSAQN---EKGISDPRQLSVPVIAK 15770

Query: 1453  DLEVVAA------TPTSLL---ISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTA 1503
             DL +  A      T T L    +  D P +      +T+ +   N P+++ T   ++ST 
Sbjct: 15771 DLVIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHK--DNVPLKQTTRVNAESTE 15828

Query: 1504  --TISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKP----SQMQVTDVQDNS 1557
               ++  +K      +  Y V     +  + + +++     +DKP      +++ +V  +S
Sbjct: 15829 NNSLLTIKDACREDVGHYVVKLTNSAGEAIETLNV---IVLDKPGPPTGPVKMDEVTADS 15885

Query: 1558  ISVKWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEG--LQPTVEYVVS 1611
             I++ W P      S +  Y V    K     T  +         TI+   L+   EY   
Sbjct: 15886 ITLSWGPPKYDGGSSINNYIV---EKRDTSTTTWQIVSATVARTTIKACRLKTGCEYQFR 15942

Query: 1612  VYAQNPSGE-----SQPLVQTAVTNIDRPKGLAFTDVDV-DSIKIAWESPQGQVSRYRVT 1665
             + A+N  G+     S+P V      +  P G     +   DS+++ W  P        + 
Sbjct: 15943 IAAENRYGKSTYLNSEPTVAQYPFKVPGPPGTPVVTLSSRDSMEVQWNEPISDGGSRVIG 16002

Query: 1666  YSSPEDGIHELF-------PAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQ 1718
             Y       + +        P P  +  T    GL  G EY   V A +     +P   ++
Sbjct: 16003 YHLERKERNSILWVKLNKTPIPQTKFKTT---GLEEGVEYEFRVSAENIVGIGKPSKVSE 16059

Query: 1719  STAIPAPTD----LKFTQVTPTSLSAQWTPPNV----QLTGYRVRVTPKEKTGPMKEINL 1770
                   P D     +   VT  S++ QW  P      ++TGY V      +   MK    
Sbjct: 16060 CYVARDPCDPPGRPEAIIVTRNSVTLQWKKPTYDGGSKITGYIVEKKELPEGRWMKASFT 16119

Query: 1771  APDSSSVVVSGLMVATKYEVSVYALKDT-LTSRPAQ--GVVTTLENVSPPRRARVTDATE 1827
                 +   V+GL+   +YE  V A     + S P++  G +T  + V PPR +      +
Sbjct: 16120 NIIDTHFEVTGLVEDHRYEFRVIARNAAGVFSEPSESTGAITARDEVDPPRISMDPKYKD 16179

Query: 1828  TTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQ-PGTDYKIYLYTL 1886
             T +  +  +       F+VDA       P  + IK D        L+   TD+   L ++
Sbjct: 16180 TIVVHAGES-------FKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSL-SV 16231

Query: 1887  NDNAR--SSPVVIDASTAIDAPS---NLRFL-------------ATTPNSLLVSWQPP-- 1926
              D  R  S   ++ A       S   N++ L               T     ++W+PP  
Sbjct: 16232 KDAVRVDSGNYILKAKNVAGERSVTVNVKVLDRPGPPEGPVVISGVTAEKCTLAWKPPLQ 16291

Query: 1927  --RARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEP 1984
                + I  YI++  +       VV           +T L  G EYT  ++A+      EP
Sbjct: 16292 DGGSDIINYIVERRETSRLVWTVVD-ANVQTLSCKVTKLLEGNEYTFRIMAVNKYGVGEP 16350

Query: 1985  LIGRKKTVQKTPFV 1998
             L   +  V K PFV
Sbjct: 16351 L-ESEPVVAKNPFV 16363



 Score = 86.3 bits (212), Expect = 3e-16
 Identities = 274/1330 (20%), Positives = 481/1330 (36%), Gaps = 177/1330 (13%)

Query: 812   DAPPDPT----VDQVDDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETAN 863
             D P  PT    +  + + S+ ++W  P+    + +T Y ++   +     TE++      
Sbjct: 20196 DRPGPPTGPVVISDITEESVTLKWEPPKYDGGSQVTNYILLKRETSTAVWTEVSATVART 20255

Query: 864   SVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFV-EVTDVK 922
              + +  L  G +Y   I A  EN+      I           T P P    +V  VT   
Sbjct: 20256 MMKVMKLTTGEEYQFRIKA--ENRFGISDHIDSACVTVKLPYTTPGPPSTPWVTNVTRES 20313

Query: 923   VTIMWTPPES----AVTGYRVDVIPVN-LPGEHGQRLPISRNTFAEVTGLSPGVTYYFKV 977
             +T+ W  P S    AV GY +++   N +  +   +L I R T  +VT +S G+ Y F+V
Sbjct: 20314 ITVGWHEPVSNGGSAVVGYHLEMKDRNSILWQKANKLVI-RTTHFKVTTISAGLIYEFRV 20372

Query: 978   FAVSHGRESKPL-TAQQTTKLDA---PTNLQFVNETDSTVLVRWTPPR----AQITGYRL 1029
             +A +     KP   ++    +DA   P N++  + + ++V + W  P     ++ITGY  
Sbjct: 20373 YAENAAGVGKPSHPSEPVLAIDACEPPRNVRITDISKNSVSLSWQQPAFDGGSKITGYI- 20431

Query: 1030  TVGLTRRGQP-----RQYNVGPSVSKYPLRNLQPASEYTVSLVA--IKGNQESP-KATGV 1081
                + RR  P     +      + +++ +  L   S+Y   + A    G+  +P +  G 
Sbjct: 20432 ---VERRDLPDGRWTKASFTNVTETQFIISGLTQNSQYEFRVFARNAVGSISNPSEVVGP 20488

Query: 1082  FTTLQ----PGSSIPPYNTEVTE----TTIV----ITWTPAPRI-GFKLGVRPSQGGEAP 1128
              T +     P   +P   TEV +    T++     I+  PAP I  +K            
Sbjct: 20489 ITCIDSYGGPVIDLPLEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVC 20548

Query: 1129  REVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDT 1188
              E T+D  SI++          Y +++        A I  +++    PP           
Sbjct: 20549 VENTTDLASILIKDADRLNSGCYELKLRNAMGSASATIRVQILDKPGPPGGPIEFKTVTA 20608

Query: 1189  GVLTVSWERSTTPD----ITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYN 1244
               +T+ W R    D    IT Y +    T+    + + E  H ++   T   +  G EY 
Sbjct: 20609 EKITLLW-RPPADDGGAKITHYIVEKRETSRVVWSMVSE--HLEECIITTTKIIKGNEYI 20665

Query: 1245  VSVYTVKDDKESVPI-SDTIIP-----AVPPPTDLRFTNIGPDTMRVTWAPP---PSIDL 1295
               V  V       P+ SD+++         PP     T I  ++M V W+ P      D+
Sbjct: 20666 FRVRAVNKYGIGEPLESDSVVAKNAFVTPGPPGIPEVTKITKNSMTVVWSRPIADGGSDI 20725

Query: 1296  TNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEY---VVSVSSVYEQHESTPLRG 1352
             + + +     K+      L  +  D    +T L   ++Y   V +V++  +   S P   
Sbjct: 20726 SGYFLEKRDKKSLGWFKVLKETIRDTRQKVTGLTENSDYQYRVCAVNAAGQGPFSEPSEF 20785

Query: 1353  RQKTGLDSPTG----IDFSDITANSFTVHWIAP----RATITGYRIRHHPEHFSGRPRED 1404
              +      P G    I  +D T +S T+ W  P     + +TGY +    E   G   E 
Sbjct: 20786 YKAADPIDPPGPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVV----EIRQGEEEEW 20841

Query: 1405  RVPHSRNSITLT-----NLTPGTEYVVSIVALN-GREESPLLIGQQSTVSDVPR----DL 1454
                 ++  +  T     NL PG  Y   + A+N   +  P+ + +     D+      DL
Sbjct: 20842 TTVSTKGEVRTTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQAKDILEAPEIDL 20901

Query: 1455  EVVAATPTSLLISWDA-----------PAVTVRYYRITYGETGGNSPVQEFTVPGSKSTA 1503
             +V   T        D            P VT R      G     S         S S  
Sbjct: 20902 DVALRTSVIAKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYS----IENTDSSSLL 20957

Query: 1504  TISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPS---QMQVTDVQDNSISV 1560
             TI  +         +    G G+  +S+  + +     +D P+   ++QV  V   ++++
Sbjct: 20958 TIPQVTRNDTGKYILTIENGVGEPKSSTVSVKV-----LDTPAACQKLQVKHVSRGTVTL 21012

Query: 1561  KWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGP-DQTEMTIEGLQPTVEYVVSVYAQ 1615
              W P      SP+  Y +    ++    T +  +     T   +  L     +   V A+
Sbjct: 21013 LWDPPLIDGGSPIINYVI--EKRDATKRTWSVVSHKCSSTSFKLIDLSEKTPFFFRVLAE 21070

Query: 1616  NPSGESQPLVQT---AVTNIDRP-KGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPED 1671
             N  G  +P   T       +  P + L+  D    S+ ++W  P          Y     
Sbjct: 21071 NEIGIGEPCETTEPVKAAEVPAPIRDLSMKDSTKTSVILSWTKPDFDGGSVITEYVVERK 21130

Query: 1672  GIHELFPAPDGEEDTAELQ--GLRPGSEYTVSVVALHDDMESQPL-IGTQSTAIPAPTDL 1728
             G  E   +  G   T E++   L+  S     V A ++   S P+ IG        P  +
Sbjct: 21131 GKGEQTWSHAGISKTCEIEVSQLKEQSVLEFRVFAKNEKGLSDPVTIG--------PITV 21182

Query: 1729  KFTQVTP-TSLSAQWTPPNVQLT---GYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMV 1784
             K   +TP   LS     P  Q+T   G+ V +    K  P   I+   D   +  S  + 
Sbjct: 21183 KELIITPEVDLS---DIPGAQVTVRIGHNVHLELPYKGKPKPSISWLKDGLPLKESEFVR 21239

Query: 1785  ATKYEVSV-YALKDTLTSRPAQ------------GVVTTLENVSPPRR----ARVTDATE 1827
              +K E  +  ++K+       +             V  T+  + PP +     R  +   
Sbjct: 21240 FSKTENKITLSIKNAKKEHGGKYTVILDNAVCRIAVPITVITLGPPSKPKGPIRFDEIKA 21299

Query: 1828  TTITISWRTKTET----ITGFQVDAVPANGQTPIQRTIKPDVR-SYTITGLQPGTDYKIY 1882
              ++ +SW    +     IT + ++      QT  +       R ++ +  L    +Y+  
Sbjct: 21300 DSVILSWDVPEDNGGGEITCYSIEK-RETSQTNWKMVCSSVARTTFKVPNLVKDAEYQFR 21358

Query: 1883  LYTLNDNARSSPVVIDASTA------IDAPSNLRFLATTPNSLLVSWQPP----RARITG 1932
             +   N    S P+V     A         P        T + + ++W  P     + +TG
Sbjct: 21359 VRAENRYGVSQPLVSSIIVAKHQFRIPGPPGKPVIYNVTSDGMSLTWDAPVYDGGSEVTG 21418

Query: 1933  YIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTV 1992
             + ++ ++  S   + V        E   TGL  G +Y   V A  +   S P    K T+
Sbjct: 21419 FHVEKKERNSILWQKVNTSPISGREYRATGLVEGLDYQFRVYAENSAGLSSPSDPSKFTL 21478

Query: 1993  QKTPFVTHPG 2002
               +P V  PG
Sbjct: 21479 AVSP-VDPPG 21487



 Score = 84.3 bits (207), Expect = 1e-15
 Identities = 337/1686 (19%), Positives = 592/1686 (35%), Gaps = 300/1686 (17%)

Query: 628   IQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISI 684
             + W+ P+    S I+ +I+  R    +  W++  I    +   I GL  G  Y+ ++I+ 
Sbjct: 8843  LNWSDPEDDGGSEITGFIIE-RKDAKMHTWRQP-IETERSKCDITGLLEGQEYKFRVIAK 8900

Query: 685   QQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWV--- 741
              ++G                PV    +        P      + TE T S+  + W    
Sbjct: 8901  NKFG-------------CGPPVEIGPILAVDPLGPPTSPERLTYTERTKSTITLDWKEPR 8947

Query: 742   -SASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQS 800
              +    + G+ +E    ++ D  +        TS  + +L   + Y   V  ++E GE  
Sbjct: 8948  SNGGSPIQGYIIEKRRHDKPDFERVNKRLCPTTSFLVENLDEHQMYEFRVKAVNEIGESE 9007

Query: 801   LILSTSQTTAPDAPPDPTVD---QVDDTSIVVRWSRP---QAPITGYRIVYSPSVEGSST 854
               L  +     D  P PT+     V   +I V+   P    A +TG  +   P +E S  
Sbjct: 9008  PSLPLNVVIQDDEVP-PTIKLRLSVRGDTIKVKAGEPVHIPADVTGLPM---PKIEWSKN 9063

Query: 855   E--LNLPETANSVTLSDLQPG-VQYNITI-YAVEENQESTPVVIQQETTGTPRS------ 904
             E  +  P  A  +T  ++     +  ++I  AV E++ +  V          R+      
Sbjct: 9064  ETVIEKPTDALQITKEEVSRSEAKTELSIPKAVREDKGTYTVTASNRLGSVFRNVHVEVY 9123

Query: 905   DTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPGEHGQRLPISRNT 960
             D    PR+L   ++      + W  P     S +T Y +D    +      + +    NT
Sbjct: 9124  DRPSPPRNLAVTDIKAESCYLTWDAPLDNGGSEITHYVIDKRDASRKKAEWEEVT---NT 9180

Query: 961   FAE----VTGLSPGVTYYFKV-----FAVSHGRESKPLTAQQTTKLDAPTNL-QFVNETD 1010
               E    +  L P   Y F+V     + +S   +S  +  Q   +L  P    + +  T 
Sbjct: 9181  AVEKRYGIWKLIPNGQYEFRVRAVNKYGISDECKSDKVVIQDPYRLPGPPGKPKVLARTK 9240

Query: 1011  STVLVRWTPP----RAQITGYRLTVGLTRRGQPRQY----------NVGPSVSKYPLRNL 1056
              ++LV WTPP     + ITGY     L +R +   Y           VG    ++ +  L
Sbjct: 9241  GSMLVSWTPPLDNGGSPITGY----WLEKREEGSPYWSRVSRAPITKVGLKGVEFNVPRL 9296

Query: 1057  QPASEYTVSLVAIKG------NQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPA 1110
                 +Y    +AI        ++ S           PG    P   + T+++I + W P 
Sbjct: 9297  LEGVKYQFRAMAINAAGIGPPSEPSDPEVAGDPIFPPGPPSCPEVKDKTKSSISLGWKPP 9356

Query: 1111  PRIGFKLGVRPSQG--GEAPREVTSD------------SGSIVVSGLTPGVEYVYTIQVL 1156
                  K G  P +G   E   E T+D            +   VV  L    +Y + ++ +
Sbjct: 9357  A----KDGGSPIKGYIVEMQEEGTTDWKRVNEPDKLITTCECVVPNLKELRKYRFRVKAV 9412

Query: 1157  RD-GQERDAPIVNKV-VTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPT- 1213
              + G+   +    ++  T +     + ++      ++  +  +   P +   R T   + 
Sbjct: 9413  NEAGESEPSDTTGEIPATDIQEEPEVFIDIGAQDCLVCKAGSQIRIPAVIKGRPTPKSSW 9472

Query: 1214  --NGQQGNSLEEVVH---ADQSSCTFDNLSPGL----------EYNVSVYTVKDDKESVP 1258
               +G+   ++++ VH    D    T +N S  +          +Y+++    K  +++  
Sbjct: 9473  EFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECKRSHTGKYSITAKN-KAGQKTAN 9531

Query: 1259  ISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEED-VAELSIS 1317
                 ++    PP DL+ ++I   + R++W  P   D  + +  Y   K   D  A   ++
Sbjct: 9532  CRVKVMDVPGPPKDLKVSDITRGSCRLSWKMPDD-DGGDRIKGYVIEKRTIDGKAWTKVN 9590

Query: 1318  P--SDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGL-------DSPTGIDFSD 1368
             P       V+ +LL   +Y   V +        P+   Q+T         D P  +    
Sbjct: 9591  PDCGSTTFVVPDLLSEQQYFFRVRAENRFGIGPPVETIQRTTARDPIYPPDPPIKLKIGL 9650

Query: 1369  ITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPRED-RVPHSRN----SITLTNLT 1419
             IT N+  + W  P+    + +T Y +       +G  +E  R  + R+      T+ +L 
Sbjct: 9651  ITKNTVHLSWKPPKNDGGSPVTHYIVECLAWDPTGTKKEAWRQCNKRDVEELQFTVEDLV 9710

Query: 1420  PGTEYVVSIVALN--GREESPLLIG-------QQSTVSDVPRDLEVVAATPTSLLIS-WD 1469
              G EY   + A+N  G  +    +G             D+   +EV   T  +++     
Sbjct: 9711  EGGEYEFRVKAVNAAGVSKPSATVGPCDCQRPDMPPSIDLKEFMEVEEGTNVNIVAKIKG 9770

Query: 1470  APAVTVRYYRITYGETGGNSPVQEFT-----VPGSKSTATISGLKPGVDYTITVYAVTGR 1524
              P  T+ +++    +     PV   T     V     T  I   +       T+ AV   
Sbjct: 9771  VPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDTGLYTITAVNNL 9830

Query: 1525  GDSPASSKPISINYRTEIDKP-SQMQVTDVQDNSISVKWLP----SSSPVTGYRVTTTPK 1579
             G    +SK + +N       P   ++   V  + +++ W P      S +T Y +     
Sbjct: 9831  G---TASKEMRLNVLGRPGPPVGPIKFESVSADQMTLSWFPPKDDGGSKITNYVIEKREA 9887

Query: 1580  NGPGPTKT---KTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVT--NI-- 1632
             N     KT    ++ P +   TI  L    EYV  + AQN  G  +PL     T  N+  
Sbjct: 9888  N----RKTWVHVSSEPKECTYTIPKLLEGHEYVFRIMAQNKYGIGEPLDSEPETARNLFS 9943

Query: 1633  --DRPKGLAFTDVDVDSIKIAWESPQ----GQVSRYRVTYSSPEDGIHELFPAPDGEEDT 1686
                 P     + V  +S+ + WE P+      V+ Y   +   +D   + +   + +   
Sbjct: 9944  VPGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPVTGY---WLEMKDTTSKRWKRVNRDPIK 10000

Query: 1687  A-------ELQGLRPGSEYTVSVVALH------DDMESQPLIGTQSTAIPAPTDLKFTQV 1733
             A       ++ GL  GS+Y   V A++        + S P       A P P   K T  
Sbjct: 10001 AMTLGVSYKVTGLIEGSDYQFRVYAINAAGVGPASLPSDPATARDPIAPPGPPFPKVTDW 10060

Query: 1734  TPTSLSAQWTPP----NVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYE 1789
             T +S   +W+PP      ++TGY V    + K    K  +     + +VV+GL     Y+
Sbjct: 10061 TKSSADLEWSPPLKDGGSKVTGYIVEYKEEGKEEWEKGKDKEVRGTKLVVTGLKEGAFYK 10120

Query: 1790  VSVYALKDTLTSRPAQGVVTTLEN----VSPPRR--ARVTD----------------ATE 1827
               V A+       P + V   +E     VSP  +  A V D                + +
Sbjct: 10121 FRVRAVNIAGIGEPGE-VTDVIEMKDRLVSPDLQLDASVRDRIVVHAGGVIRIIAYVSGK 10179

Query: 1828  TTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDV--RSYTITGLQPGTDYKIYLYT 1885
                T++W     T+              P + TI+      S  I   Q        L  
Sbjct: 10180 PPPTVTWNMNERTL--------------PQEATIETTAISSSMVIKNCQRSHQGVYSLLA 10225

Query: 1886  LNDNARSSPVVIDASTAIDAPSNLRFLA--TTPNSLLVSWQPPR----ARITGYIIKYEK 1939
              N+       +I     +  P    FLA   T  S  ++W  P     + IT Y+I  EK
Sbjct: 10226 KNEAGERKKTIIVDVLDVPGPVGTPFLAHNLTNESCKLTWFSPEDDGGSPITNYVI--EK 10283

Query: 1940  PGSPPREVVPRPRPGVTE-ATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQKTPFV 1998
               S  R   P       + AT+ GL  G  Y   + A             + ++   PFV
Sbjct: 10284 RESDRRAWTPVTYTVTRQNATVQGLIQGKAYFFRIAA-------------ENSIGMGPFV 10330

Query: 1999  THPGYDTGNGIQLPGTSGQQPSVGQQMIFEEHGFRRTTPPTTATPIRHRPRPYPPNVGQE 2058
                                     + ++  E             PI    RP    V + 
Sbjct: 10331 ---------------------ETSEALVIRE-------------PITVPERPEDLEVKEV 10356

Query: 2059  ALSQTTISWAP--FQDTSE---YIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYN 2113
               +  T++W P  +   SE   Y++    +GT++          S   T+ GL  G TY 
Sbjct: 10357 TKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEKFHKVTNDNLLSRKYTVKGLKEGDTYE 10416

Query: 2114  IIVEAL 2119
               V A+
Sbjct: 10417 YRVSAV 10422



 Score = 84.3 bits (207), Expect = 1e-15
 Identities = 134/644 (20%), Positives = 244/644 (37%), Gaps = 79/644 (12%)

Query: 1421  GTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAP----AVTVR 1476
             G +Y++    + G +  P+ +            ++V   T     ++W  P       + 
Sbjct: 17321 GGQYILRASNVAGSKSFPVNVKVLDRPGPPEGPVQVTGVTSEKCSLTWSPPLQDGGSDIS 17380

Query: 1477  YYRITYGETGGNSPVQEFTVPGSK---STATISGLKPGVDYTITVYAVTGRG-DSPASSK 1532
             +Y +   ET   +    +TV  S+   ++  ++ L  G +Y   + AV   G   P  S 
Sbjct: 17381 HYVVEKRETSRLA----WTVVASEVVTNSLKVTKLLEGNEYVFRIMAVNKYGVGEPLESA 17436

Query: 1533  PISINYRTEID-KPSQMQVTDVQDNSISVKW-LPSS---SPVTGYRVTTTPKNGPGPTKT 1587
             P+ +     +   P  ++VT++  +S++V W  P S   S + GY V    ++G    K 
Sbjct: 17437 PVLMKNPFVLPGPPKSLEVTNIAKDSMTVCWNRPDSDGGSEIIGYIVEKRDRSGIRWIKC 17496

Query: 1588  KTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTA-------VTNIDRPKGLAF 1640
                      + + GL    EY   V A+N +G  +P   T        V     P     
Sbjct: 17497 NKRRITDLRLRVTGLTEDHEYEFRVSAENAAGVGEPSPATVYYKACDPVFKPGPPTNAHI 17556

Query: 1641  TDVDVDSIKIAWESP----QGQVSRYRVTYSSPEDGIHELFPAPDGEEDTA-ELQGLRPG 1695
              D   +SI +AW  P      ++  Y V     ++   ++     G   T  E+  L   
Sbjct: 17557 VDTTKNSITLAWGKPIYDGGSEILGYVVEICKADEEEWQIVTPQTGLRVTRFEISKLTEH 17616

Query: 1696  SEYTVSVVALHDDMESQPLIGT-QSTAIPAPTDLKFTQVTPT-SLSAQWTPPNVQLTGYR 1753
              EY + V AL+        +G  ++T++P     +     P   L ++     V   G  
Sbjct: 17617 QEYKIRVCALNK-------VGLGEATSVPGTVKPEDKLEAPELDLDSELRKGIVVRAGGS 17669

Query: 1754  VRVTPKEKTGPMKEINLAPD----SSSVVVSGLMVATKYEVS----------VYALKDTL 1799
              R+    K  P  EI  + +    +  V +   +  T+  +           +  L+++ 
Sbjct: 17670 ARIHIPFKGRPTPEITWSREEGEFTDKVQIEKGVNYTQLSIDNCDRNDAGKYILKLENSS 17729

Query: 1800  TSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKT----ETITGFQVDAVPANGQT 1855
              S+ A   V  L+   PP+   V +  + +  + W          +  + +D   +  + 
Sbjct: 17730 GSKSAFVTVKVLDTPGPPQNLAVKEVRKDSAFLVWEPPIIDGGAKVKNYVIDKRESTRKA 17789

Query: 1856  PIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPV-VIDASTAIDAPS-----NL 1909
                 + K    S+ +  L  G  Y   +   N+     PV  +DA  A + PS      L
Sbjct: 17790 YANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFGVGVPVETVDAVKAAEPPSPPGKVTL 17849

Query: 1910  RFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEP 1965
               ++ T  SL+  W+ P     +R+ GY+++ +  G+    +V   +  V  A +TGL  
Sbjct: 17850 TDVSQTSASLM--WEKPEHDGGSRVLGYVVEMQPKGTEKWSIVAESK--VCNAVVTGLSS 17905

Query: 1966  GTEYTIYVIALKNNQKSE------PLIGRKKTVQ---KTPFVTH 2000
             G EY   V A     KS+      P+I +  T+Q   K PF T+
Sbjct: 17906 GQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKLPFNTY 17949



 Score = 82.4 bits (202), Expect = 5e-15
 Identities = 130/589 (22%), Positives = 217/589 (36%), Gaps = 70/589 (11%)

Query: 1505  ISGLKPGVDYTITVYAVTGRG-DSPASSKPI-SINYRTEIDKPSQMQVTDVQDNSISVKW 1562
             ++ L  G +YT  + AV   G   P  S+P+ + N     D P   +VT V  +S+ V W
Sbjct: 16326 VTKLLEGNEYTFRIMAVNKYGVGEPLESEPVVAKNPFVVPDAPKAPEVTTVTKDSMIVVW 16385

Query: 1563  -LPSS---SPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPS 1618
               P+S   S + GY +    K G   T+       +  + + GL    +Y   V A+N +
Sbjct: 16386 ERPASDGGSEILGYVLEKRDKEGIRWTRCHKRLIGELRLRVTGLIENHDYEFRVSAENAA 16445

Query: 1619  GESQPLVQTA-------VTNIDRPKGLAFTDVDVDSIKIAWESP----QGQVSRYRVTYS 1667
             G S+P   +A       +     P      D+   S+ ++W  P      ++  Y V   
Sbjct: 16446 GLSEPSPPSAYQKACDPIYKPGPPNNPKVIDITRSSVFLSWSKPIYDGGCEIQGYIVEKC 16505

Query: 1668  SPEDGIHELFPAPDGEEDT-AELQGLRPGSEYTVSVVAL-------HDDMESQPLIGTQS 1719
                 G   +   P G   T  E++ L    EY   + A+       H D+    ++  + 
Sbjct: 16506 DVSVGEWTMCTPPTGINKTNIEVEKLLEKHEYNFRICAINKAGVGEHADVPGPIIVEEKL 16565

Query: 1720  TAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEK----TGPMKEINLAPDSS 1775
              A     DL+  ++                   + R TP+ K     G +++  +   +S
Sbjct: 16566 EAPDIDLDLELRKIINIRAGGSLR----LFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTS 16621

Query: 1776  SVVVSGLMVATKYEVSVY--ALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITIS 1833
             S     L    +Y+   Y   L+++  ++ A   V  L+  SPP   +VT+ T+ +++I+
Sbjct: 16622 SFTSLVLDNVNRYDSGKYTLTLENSSGTKSAFVTVRVLDTPSPPVNLKVTEITKDSVSIT 16681

Query: 1834  WRTKT----ETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDN 1889
             W          I  + V+   A  ++           S+ I  LQ G  Y   +   N+ 
Sbjct: 16682 WEPPLLDGGSKIKNYIVEKREATRKSYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAENEY 16741

Query: 1890  ARSSPV----VIDASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPG 1941
                 P      I  +     P  +     T NS+ +SW  P     ++I  YI++ +   
Sbjct: 16742 GIGLPAQTADPIKVAEVPQPPGKITVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKH 16801

Query: 1942  SPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQKTPFVTHP 2001
             S       R +    +A IT L  G EY   V+A+    +S+P       V K   V  P
Sbjct: 16802 SEKWSECARVKS--LQAVITNLTQGEEYLFRVVAVNEKGRSDPRSLAVPIVAK-DLVIEP 16858

Query: 2002  GYDTGNGIQLPGTSGQQPSVGQQMIFEEHGFRRTTPPTTATPIRHRPRP 2050
                       P  S     VGQ +  E              PI  RP+P
Sbjct: 16859 DVK-------PAFSSYSVQVGQDLKIE-------------VPISGRPKP 16887



 Score = 82.0 bits (201), Expect = 6e-15
 Identities = 266/1310 (20%), Positives = 442/1310 (33%), Gaps = 219/1310 (16%)

Query: 731   ITASSFVVSWVSASDTVSGFRVEYELSE-EGDEPQYLDLPSTAT--SVNIPDLLPGRKYI 787
             ++A    +SW    D        Y + + E +   ++ + S     +  IP LL G +Y+
Sbjct: 9857  VSADQMTLSWFPPKDDGGSKITNYVIEKREANRKTWVHVSSEPKECTYTIPKLLEGHEYV 9916

Query: 788   V-----NVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ----API 838
                   N Y I E  +     + +  + P AP  PTV  V   S+ V W  P+    +P+
Sbjct: 9917  FRIMAQNKYGIGEPLDSEPETARNLFSVPGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPV 9976

Query: 839   TGYRIVYSPSVEGSSTELNLPETANSVTL------SDLQPGVQYNITIYAVEENQESTPV 892
             TGY +    +       +N  +   ++TL      + L  G  Y   +YA+       P 
Sbjct: 9977  TGYWLEMKDTTSKRWKRVN-RDPIKAMTLGVSYKVTGLIEGSDYQFRVYAINAAGVG-PA 10034

Query: 893   VIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPG 948
              +  +          P P   +  + T     + W+PP     S VTGY V+        
Sbjct: 10035 SLPSDPATARDPIAPPGPPFPKVTDWTKSSADLEWSPPLKDGGSKVTGYIVEYKEEGKEE 10094

Query: 949   EHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGR-----------ESKPLTAQQTTKL 997
                 +    R T   VTGL  G  Y F+V AV+              E K        +L
Sbjct: 10095 WEKGKDKEVRGTKLVVTGLKEGAFYKFRVRAVNIAGIGEPGEVTDVIEMKDRLVSPDLQL 10154

Query: 998   DAPTNLQFVNETDSTV----LVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSV--SKY 1051
             DA    + V      +     V   PP        +T  +  R  P++  +  +   S  
Sbjct: 10155 DASVRDRIVVHAGGVIRIIAYVSGKPPPT------VTWNMNERTLPQEATIETTAISSSM 10208

Query: 1052  PLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNT-EVTETTIVITWTP- 1109
              ++N Q + +   SL+A     E  K   V     PG    P+    +T  +  +TW   
Sbjct: 10209 VIKNCQRSHQGVYSLLAKNEAGERKKTIIVDVLDVPGPVGTPFLAHNLTNESCKLTWFSP 10268

Query: 1110  -----APRIGFKLGVRPS-QGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRD----- 1158
                  +P   + +  R S +    P   T    +  V GL  G  Y + I          
Sbjct: 10269 EDDGGSPITNYVIEKRESDRRAWTPVTYTVTRQNATVQGLIQGKAYFFRIAAENSIGMGP 10328

Query: 1159  -GQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSW---ERSTTPDITGYRITTTPTN 1214
               +  +A ++ + +T    P +L ++       +T++W   +     +I  Y + +    
Sbjct: 10329 FVETSEALVIREPITVPERPEDLEVK-EVTKNTVTLTWNPPKYDGGSEIINYVLESRLIG 10387

Query: 1215  GQQGNSLEEVVHADQSSCTFDNLSPG--LEYNVSVYTV----KDDKESVPISDTIIPAVP 1268
              ++ + +    +      T   L  G   EY VS   +    K    + PI  T    + 
Sbjct: 10388 TEKFHKVTN-DNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGKPSFCTKPI--TCKDELA 10444

Query: 1269  PPT---------DLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAE---LSI 1316
             PPT          +R       T R +  P P +         S  K+E DV E     I
Sbjct: 10445 PPTLHLDFRDKLTIRVGEAFALTGRYSGKPKPKV---------SWFKDEADVLEDDRTHI 10495

Query: 1317  SPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSP----TGIDFSDITAN 1372
               +   + L  +            V E    +     Q   +D P      + F ++T +
Sbjct: 10496 KTTPATLALEKIKAKRSDSGKYCVVVENSTGSRKGFCQVNVVDRPGPPVGPVSFDEVTKD 10555

Query: 1373  SFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVP----HSRNSITLTNLTPGTEYVVSI 1428
                + W  P     G +I ++        ++  +P     ++ +  ++ L  G +Y+  I
Sbjct: 10556 YMVISW-KPPLDDGGSKITNYIIEKKEVGKDVWMPVTSASAKTTCKVSKLLEGKDYIFRI 10614

Query: 1429  VALNGREESPLLIG------QQSTVSDVPRDLEVVAATPTSLLISWDAP----------- 1471
              A N    S  L+        +  V D P    V   T  S L++W+ P           
Sbjct: 10615 HAENLYGISDPLVSDSMKAKDRFRVPDAPDQPIVTEVTKDSALVTWNKPHDGGKPITNYI 10674

Query: 1472  -----AVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVT--GR 1524
                   ++ R+ R+T        P  +F VP          L  G  Y   V A    G 
Sbjct: 10675 LEKRETMSKRWARVTKDPI---HPYTKFRVP---------DLLEGCQYEFRVSAENEIGI 10722

Query: 1525  GDSPASSKPISINYRTEIDKPS---QMQVTDVQDNSISVKWLP----SSSPVTGYRVTTT 1577
             GD    SKP+    +  I KPS     +  D   NS+ + W P      S + GY +   
Sbjct: 10723 GDPSPPSKPVFA--KDPIAKPSPPVNPEAIDTTCNSVDLTWQPPRHDGGSKILGY-IVEY 10779

Query: 1578  PKNGPGPTKTKTAGPD---QTEMTIEGLQPTVEYVVSVYAQNPSGESQP-------LVQT 1627
              K G    +     P+   +T+  + GL+    Y   V A N +GES P       LV+ 
Sbjct: 10780 QKVGDEEWRRANHTPESCPETKYKVTGLRDGQTYKFRVLAVNAAGESDPAHVPEPVLVKD 10839

Query: 1628  AV--------TNIDRPKGLAFTDV--------DVDSIKIAWESPQGQVSRYRVTYSSPED 1671
              +         N+ R + +   D          V   K+ W+              +P  
Sbjct: 10840 RLEPPELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARIDVTPVG 10899

Query: 1672  GIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFT 1731
                E+  A   +     L    P    TVSV  L  D                P DL+ +
Sbjct: 10900 SKLEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDKPG------------PPRDLEVS 10947

Query: 1732  QVTPTSLSAQWTPP----NVQLTGYRVR-------------VTPKEKTGPMKEINLAPDS 1774
             ++   S    W  P       +T Y V               T K+K+   K +N     
Sbjct: 10948 EIRKDSCYLTWKEPLDDGGSVITNYVVERRDVASAQWSPLSATSKKKSHFAKHLN----E 11003

Query: 1775  SSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISW 1834
              +  +  +    +Y    +      T +P +  +  L    PP+     D  +T +++ W
Sbjct: 11004 GNQYLFRVAAENQYGRGPF----VETPKPIK-ALDPLHPPGPPKDLHHVDVDKTEVSLVW 11058

Query: 1835  ----RTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYK 1880
                 R     ITG+ V+      Q  I+     ++    +TGLQ G  Y+
Sbjct: 11059 NKPDRDGGSPITGYLVEYQEEGTQDWIKFKTVTNLEC-VVTGLQQGKTYR 11107



 Score = 80.9 bits (198), Expect = 1e-14
 Identities = 248/1194 (20%), Positives = 435/1194 (36%), Gaps = 142/1194 (11%)

Query: 908   PSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAE 963
             P    +Q   VT  K ++ W+PP     S ++ Y V+    +          +  N+  +
Sbjct: 17349 PPEGPVQVTGVTSEKCSLTWSPPLQDGGSDISHYVVEKRETSRLAWTVVASEVVTNSL-K 17407

Query: 964   VTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDA------PTNLQFVNETDSTVLVRW 1017
             VT L  G  Y F++ AV+     +PL +      +       P +L+  N    ++ V W
Sbjct: 17408 VTKLLEGNEYVFRIMAVNKYGVGEPLESAPVLMKNPFVLPGPPKSLEVTNIAKDSMTVCW 17467

Query: 1018  TPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQ---------PASEYTVSLVA 1068
               P +   G    +G     + R        +K  + +L+            E+ VS   
Sbjct: 17468 NRPDSD--GGSEIIGYIVEKRDRSGIRWIKCNKRRITDLRLRVTGLTEDHEYEFRVSAEN 17525

Query: 1069  IKGNQESPKATGVFTTLQPGSSI-PPYNTEVTETT---IVITWTP------APRIGFKLG 1118
               G  E   AT  +    P     PP N  + +TT   I + W        +  +G+ + 
Sbjct: 17526 AAGVGEPSPATVYYKACDPVFKPGPPTNAHIVDTTKNSITLAWGKPIYDGGSEILGYVVE 17585

Query: 1119  VRPSQGGEAPREVTSDSGSIV----VSGLTPGVEYVYTIQVLRD---GQERDAPIVNKVV 1171
             +  +   E  + VT  +G  V    +S LT   EY   +  L     G+    P   K  
Sbjct: 17586 ICKADEEEW-QIVTPQTGLRVTRFEISKLTEHQEYKIRVCALNKVGLGEATSVPGTVKPE 17644

Query: 1172  TPLSPPTNLHLEANPDTGVLT---------VSWERSTTPDITGYRITTTPTNGQQGNSLE 1222
               L  P  L L++    G++          + ++   TP+IT  R     T+  Q   +E
Sbjct: 17645 DKLEAP-ELDLDSELRKGIVVRAGGSARIHIPFKGRPTPEITWSREEGEFTDKVQ---IE 17700

Query: 1223  EVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRFTNIGPDT 1282
             + V+  Q S    + +   +Y + +      K +  ++  ++    PP +L    +  D+
Sbjct: 17701 KGVNYTQLSIDNCDRNDAGKYILKLENSSGSKSAF-VTVKVLDTPGPPQNLAVKEVRKDS 17759

Query: 1283  MRVTWAPPPSIDLTNFLVRYSPVKNEED---VAELSISPSDNAVVLTNLLPGTEYVVSVS 1339
               + W PP  ID    +  Y   K E      A +S   S  +  + NL  G  Y   V 
Sbjct: 17760 AFLVWEPP-IIDGGAKVKNYVIDKRESTRKAYANVSSKCSKTSFKVENLTEGAIYYFRVM 17818

Query: 1340  SVYEQHESTPLR---GRQKTGLDSPTG-IDFSDITANSFTVHWIAPR----ATITGYRIR 1391
             +  E     P+      +     SP G +  +D++  S ++ W  P     + + GY + 
Sbjct: 17819 AENEFGVGVPVETVDAVKAAEPPSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVE 17878

Query: 1392  HHPEHFSGRPREDRVPHSRN-SITLTNLTPGTEYVVSIVALNGREES-PLLIGQQSTVSD 1449
               P+   G  +   V  S+  +  +T L+ G EY   + A N + +S P ++G      D
Sbjct: 17879 MQPK---GTEKWSIVAESKVCNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKD 17935

Query: 1450  VPRDLEVVAATPTSLL-----ISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTAT 1504
             +     +     T  +     +  + P +      I++ + G   P+++ T    + TAT
Sbjct: 17936 LTIQPSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDG--EPLKQTTRVNVEETAT 17993

Query: 1505  --ISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKP-SQMQVTDVQDNSISVK 1561
               +  +K G       Y VT    +  +++ +S+    +   P   ++  +V  + + + 
Sbjct: 17994 STVLHIKEGNKDDFGKYTVTATNSAGTATENLSVIVLEKPGPPVGPVRFDEVSADFVVIS 18053

Query: 1562  WLPSS----SPVTGYRV-----TTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSV 1612
             W P +      ++ Y V     TTT  +    T  +T       + I  L+   EY   +
Sbjct: 18054 WEPPAYTGGCQISNYIVEKRDTTTTTWHMVSATVARTT------IKITKLKTGTEYQFRI 18107

Query: 1613  YAQNPSGESQPLVQTAVT-----NIDRPKGLAF-TDVDVDSIKIAWESPQGQVSRYRVTY 1666
             +A+N  G+S PL   AV          P G  F T +  D + + W  P        + Y
Sbjct: 18108 FAENRYGKSAPLDSKAVIVQYPFKEPGPPGTPFVTSISKDQMLVQWHEPVNDGGTKIIGY 18167

Query: 1667  SSPEDGIHELF-------PAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQS 1719
                +   + +        P  D +  T    GL  G EY   V A +     +P   ++ 
Sbjct: 18168 HLEQKEKNSILWVKLNKTPIQDTKFKTT---GLDEGLEYEFKVSAENIVGIGKPSKVSEC 18224

Query: 1720  TAIPAPTDL----KFTQVTPTSLSAQWTPP----NVQLTGYRVRVTPKEKTGPMKEINLA 1771
                  P D     +   +T  +++ +W  P      ++TGY V          MK     
Sbjct: 18225 FVARDPCDPPGRPEAIVITRNNVTLKWKKPAYDGGSKITGYIVEKKDLPDGRWMKASFTN 18284

Query: 1772  PDSSSVVVSGLMVATKYEVSVYALKDTLT-SRPAQ--GVVTTLENVSPPRRAR------- 1821
                +   VSGL+   +YE  V A       S P+   G +T  + +  P  +        
Sbjct: 18285 VLETEFTVSGLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARDEIDAPNASLDPKYKDV 18344

Query: 1822  -VTDATET-TITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQP-GTD 1878
              V  A ET  +    R K      +  D      +T  +  IK  ++  T+       TD
Sbjct: 18345 IVVHAGETFVLEADIRGKPIPDVVWSKDGKELE-ETAARMEIKSTIQKTTLVVKDCIRTD 18403

Query: 1879  YKIYLYTLND--NARSSPVVIDASTAIDAPSN-LRFLATTPNSLLVSWQPPR----ARIT 1931
                Y+  L++    +S P+ +        P   L+    T     ++W PP     A I+
Sbjct: 18404 GGQYILKLSNVGGTKSIPITVKVLDRPGPPEGPLKVTGVTAEKCYLAWNPPLQDGGANIS 18463

Query: 1932  GYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPL 1985
              YII+  +        V      +    +T L PG EY   V+A+      EPL
Sbjct: 18464 HYIIEKRETSRLSWTQVSTEVQALNYK-VTKLLPGNEYIFRVMAVNKYGIGEPL 18516



 Score = 78.6 bits (192), Expect = 7e-14
 Identities = 169/767 (22%), Positives = 275/767 (35%), Gaps = 120/767 (15%)

Query: 601   PLQTYPSSSGPVEVFITETPSQPN-------SHPIQWNAPQ---PSHISKYILRWRPKNS 650
             P +T P       VF+   PS+P        +  I W  P     + I+ Y + ++  + 
Sbjct: 19696 PSETSPLIRAEDPVFLPSPPSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEYKKSDD 19755

Query: 651   VGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNT 710
                WK +        YTI GL  G  Y  ++ S+ + G  +        + +S P  +  
Sbjct: 19756 TD-WKTSIQSLRGTEYTISGLTTGAEYVFRVKSVNKVGASD-------PSDSSDPQIAKE 19807

Query: 711   VTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVS--GFRVEYELSEEGDEP----Q 764
                E     PL       +E+  +  V +  S + TV   G  V   L  + D       
Sbjct: 19808 REEE-----PLFDID---SEMRKTLIVKAGASFTMTVPFRGRPVPNVLWSKPDTDLRTRA 19859

Query: 765   YLDLPSTATSVNIPDLL--PGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQV 822
             Y+D   + TS+ I +       KY + +  +      +L++    T  P  P + TV  V
Sbjct: 19860 YVDTTDSRTSLTIENANRNDSGKYTLTIQNVLSAASLTLVVKVLDTPGP--PTNITVQDV 19917

Query: 823   DDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNI 878
                S V+ W  P+    AP+  Y I    + + +   +       S  +++LQ G  Y  
Sbjct: 19918 TKESAVLSWDVPENDGGAPVKNYHIEKREASKKAWVSVTNNCNRLSYKVTNLQEGAIYYF 19977

Query: 879   TIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAV 934
              +    E     P   ++   G   ++    P  L    ++   V++ W  PE    S +
Sbjct: 19978 RVSGENEFGVGIPAETKE---GVKITEKPSPPEKLGVTSISKDSVSLTWLKPEHDGGSRI 20034

Query: 935   TGYRVDVIPVNLPGEHGQR----LPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKP-- 988
               Y V+ +      E GQ+      ++++T   V+GL     Y+F+VFA +    S P  
Sbjct: 20035 VHYVVEAL------EKGQKNWVKCAVAKSTHHVVSGLRENSEYFFRVFAENQAGLSDPRE 20088

Query: 989   -LTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPS 1047
              L      +   P  +   N    TV VR         G  L V +   G+P    V  S
Sbjct: 20089 LLLPVLIKEQLEPPEIDMKNFPSHTVYVR--------AGSNLKVDIPISGKPLP-KVTLS 20139

Query: 1048  VSKYPLR-NLQPASEYTV---------SLVAIKGNQESPKATGVFTTL---------QPG 1088
                 PL+  ++  +E T          S+ A  G  E   A    TT          +PG
Sbjct: 20140 RDGVPLKATMRFNTEITAENLTINLKESVTADAGRYEITAANSSGTTKAFINIVVLDRPG 20199

Query: 1089  SSI-PPYNTEVTETTIVITWTPAPRIG-------FKLGVRPSQGGEAPREVTSDSGSIVV 1140
                 P   +++TE ++ + W P    G         L    S         T     + V
Sbjct: 20200 PPTGPVVISDITEESVTLKWEPPKYDGGSQVTNYILLKRETSTAVWTEVSATVARTMMKV 20259

Query: 1141  SGLTPGVEYVYTIQV-----LRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSW 1195
               LT G EY + I+      + D  +     V    T   PP+   +  N     +TV W
Sbjct: 20260 MKLTTGEEYQFRIKAENRFGISDHIDSACVTVKLPYTTPGPPSTPWV-TNVTRESITVGW 20318

Query: 1196  ERSTT---PDITGYRITTTPTNG---QQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYT 1249
                 +     + GY +     N    Q+ N L  V+       T   +S GL Y   VY 
Sbjct: 20319 HEPVSNGGSAVVGYHLEMKDRNSILWQKANKL--VIRTTHFKVT--TISAGLIYEFRVYA 20374

Query: 1250  V------KDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPP 1290
                    K    S P+    I A  PP ++R T+I  +++ ++W  P
Sbjct: 20375 ENAAGVGKPSHPSEPV--LAIDACEPPRNVRITDISKNSVSLSWQQP 20419



 Score = 77.8 bits (190), Expect = 1e-13
 Identities = 327/1588 (20%), Positives = 561/1588 (35%), Gaps = 285/1588 (17%)

Query: 737   VVSWVSASDT----VSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQ 792
             +++W    D     ++GF +E + ++     Q ++  +  +  +I  LL G++Y   V  
Sbjct: 8842  LLNWSDPEDDGGSEITGFIIERKDAKMHTWRQPIE--TERSKCDITGLLEGQEYKFRVIA 8899

Query: 793   ISEDG-----EQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQA----PITGYRI 843
              ++ G     E   IL+      P +P   T  +   ++I + W  P++    PI GY I
Sbjct: 8900  KNKFGCGPPVEIGPILAVDPLGPPTSPERLTYTERTKSTITLDWKEPRSNGGSPIQGYII 8959

Query: 844   VY----SPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTP-----VVI 894
                    P  E  +  L  P T  S  + +L     Y   + AV E  ES P     VVI
Sbjct: 8960  EKRRHDKPDFERVNKRL-CPTT--SFLVENLDEHQMYEFRVKAVNEIGESEPSLPLNVVI 9016

Query: 895   QQETTG-------TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLP 947
             Q +          + R DT+     ++  E   +   +   P           VI     
Sbjct: 9017  QDDEVPPTIKLRLSVRGDTIK----VKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTD 9072

Query: 948   GEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSH----GRESKPLTAQQTTKLDAPTNL 1003
                  +  +SR+       +   V      + V+     G   + +  +   +   P NL
Sbjct: 9073  ALQITKEEVSRSEAKTELSIPKAVREDKGTYTVTASNRLGSVFRNVHVEVYDRPSPPRNL 9132

Query: 1004  QFVNETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSV--SKYPLRNLQ 1057
                +    +  + W  P     ++IT Y +      R +     V  +    +Y +  L 
Sbjct: 9133  AVTDIKAESCYLTWDAPLDNGGSEITHYVIDKRDASRKKAEWEEVTNTAVEKRYGIWKLI 9192

Query: 1058  PASEYTVSLVAIKGNQESPKATGVFTTLQ-----PGSSIPPYNTEVTETTIVITWTP--- 1109
             P  +Y   + A+     S +       +Q     PG    P     T+ +++++WTP   
Sbjct: 9193  PNGQYEFRVRAVNKYGISDECKSDKVVIQDPYRLPGPPGKPKVLARTKGSMLVSWTPPLD 9252

Query: 1110  ---APRIGFKLGVRP------SQGGEAPREVTSDSG-SIVVSGLTPGVEYVYTIQVLR-- 1157
                +P  G+ L  R       S+   AP       G    V  L  GV+Y +    +   
Sbjct: 9253  NGGSPITGYWLEKREEGSPYWSRVSRAPITKVGLKGVEFNVPRLLEGVKYQFRAMAINAA 9312

Query: 1158  ----DGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWE---RSTTPDITGYRITT 1210
                   +  D  +    + P  PP+   ++    + + ++ W+   +     I GY +  
Sbjct: 9313  GIGPPSEPSDPEVAGDPIFPPGPPSCPEVKDKTKSSI-SLGWKPPAKDGGSPIKGYIVEM 9371

Query: 1211  TP---TNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAV 1267
                  T+ ++ N  ++++   +  C   NL    +Y   V  V +  ES P SDT     
Sbjct: 9372  QEEGTTDWKRVNEPDKLITTCE--CVVPNLKELRKYRFRVKAVNEAGESEP-SDTT--GE 9426

Query: 1268  PPPTDLR-----FTNIGPDTMRVTWA-------------PPPS----IDLTNFLVRYSPV 1305
              P TD++     F +IG     V  A             P P      D          V
Sbjct: 9427  IPATDIQEEPEVFIDIGAQDCLVCKAGSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGV 9486

Query: 1306  KNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTP-LRGRQKTGLDSPTGI 1364
              +  + A+L  + + + +++           S+++  +  + T   R +       P  +
Sbjct: 9487  HDIPEDAQLETAENSSVIIIPECKRSHTGKYSITAKNKAGQKTANCRVKVMDVPGPPKDL 9546

Query: 1365  DFSDITANSFTVHWIAPRAT----ITGYRIRHHPEHFSGRPREDRVPH-SRNSITLTNLT 1419
               SDIT  S  + W  P       I GY I        G+      P     +  + +L 
Sbjct: 9547  KVSDITRGSCRLSWKMPDDDGGDRIKGYVIEKRT--IDGKAWTKVNPDCGSTTFVVPDLL 9604

Query: 1420  PGTEYVVSIVALNGREESPLLIGQQSTVS-------DVPRDLEVVAATPTSLLISWDAPA 1472
                +Y   + A N     P +   Q T +       D P  L++   T  ++ +SW  P 
Sbjct: 9605  SEQQYFFRVRAENRFGIGPPVETIQRTTARDPIYPPDPPIKLKIGLITKNTVHLSWKPP- 9663

Query: 1473  VTVRYYRITYGETGGNSPVQEFTVP-------GSKSTA--------------TISGLKPG 1511
                        +  G SPV  + V        G+K  A              T+  L  G
Sbjct: 9664  -----------KNDGGSPVTHYIVECLAWDPTGTKKEAWRQCNKRDVEELQFTVEDLVEG 9712

Query: 1512  VDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTG 1571
              +Y   V AV   G S  S+             P   Q  D+   SI +K        T 
Sbjct: 9713  GEYEFRVKAVNAAGVSKPSATV----------GPCDCQRPDMPP-SIDLKEFMEVEEGTN 9761

Query: 1572  YRVTTTPKNGPGPT----KTKTAGPDQTEMTIEGLQPTVEYV----VSVYAQNPSGESQP 1623
               +    K  P PT    K     PD  E  +         V      V  Q+   ++  
Sbjct: 9762  VNIVAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDTGL 9821

Query: 1624  LVQTAVTNIDR---------------PKG-LAFTDVDVDSIKIAWESPQ----GQVSRYR 1663
                TAV N+                 P G + F  V  D + ++W  P+     +++ Y 
Sbjct: 9822  YTITAVNNLGTASKEMRLNVLGRPGPPVGPIKFESVSADQMTLSWFPPKDDGGSKITNYV 9881

Query: 1664  VTY--SSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVA-----LHDDMESQPLIG 1716
             +    ++ +  +H    + + +E T  +  L  G EY   ++A     + + ++S+P   
Sbjct: 9882  IEKREANRKTWVHV---SSEPKECTYTIPKLLEGHEYVFRIMAQNKYGIGEPLDSEPETA 9938

Query: 1717  TQSTAIP-APTDLKFTQVTPTSLSAQWTPPNVQ----LTGYRVRVTPKEKTGPM-KEINL 1770
                 ++P AP     + VT  S++  W  P       +TGY + +  K+ T    K +N 
Sbjct: 9939  RNLFSVPGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPVTGYWLEM--KDTTSKRWKRVNR 9996

Query: 1771  APDSS-----SVVVSGLMVATKYEVSVYALKD------TLTSRPAQGVVTTLENVSPPRR 1819
              P  +     S  V+GL+  + Y+  VYA+        +L S PA    T  + ++PP  
Sbjct: 9997  DPIKAMTLGVSYKVTGLIEGSDYQFRVYAINAAGVGPASLPSDPA----TARDPIAPPGP 10052

Query: 1820  A--RVTDATETTITISWRTKTET----ITGFQVDAVPANGQTPIQRTIKPDVRS--YTIT 1871
                +VTD T+++  + W    +     +TG+ V+     G+   ++    +VR     +T
Sbjct: 10053 PFPKVTDWTKSSADLEWSPPLKDGGSKVTGYIVE-YKEEGKEEWEKGKDKEVRGTKLVVT 10111

Query: 1872  GLQPGTDYKIYLYTLNDNARSSPV----VIDASTAIDAPSNLRFLATTPNSLLVSWQPPR 1927
             GL+ G  YK  +  +N      P     VI+    + +P +L+  A+  + ++V      
Sbjct: 10112 GLKEGAFYKFRVRAVNIAGIGEPGEVTDVIEMKDRLVSP-DLQLDASVRDRIVVH-AGGV 10169

Query: 1928  ARITGYIIKYEKPGSPPREVV--PRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPL 1985
              RI  Y+      G PP  V      R    EATI      T      + +KN Q+S   
Sbjct: 10170 IRIIAYV-----SGKPPPTVTWNMNERTLPQEATIE-----TTAISSSMVIKNCQRSHQG 10219

Query: 1986  I----------GRKKTV----------QKTPFVTHPGYDTGNGIQL----PGTSGQQPSV 2021
             +           RKKT+            TPF+ H    T    +L    P   G  P +
Sbjct: 10220 VYSLLAKNEAGERKKTIIVDVLDVPGPVGTPFLAHNL--TNESCKLTWFSPEDDGGSP-I 10276

Query: 2022  GQQMIFEEHGFRRTTPPTTATPIRHRPRPYPPNVGQ----EALSQTTISWAPFQDTSEYI 2077
                +I +    RR   P T T  R          G+       ++ +I   PF +TSE +
Sbjct: 10277 TNYVIEKRESDRRAWTPVTYTVTRQNATVQGLIQGKAYFFRIAAENSIGMGPFVETSEAL 10336

Query: 2078  ISCHPVGTDEEPLQFRVPG-TSTSATLT 2104
             +   P+   E P    V   T  + TLT
Sbjct: 10337 VIREPITVPERPEDLEVKEVTKNTVTLT 10364



 Score = 77.0 bits (188), Expect = 2e-13
 Identities = 270/1352 (19%), Positives = 474/1352 (35%), Gaps = 184/1352 (13%)

Query: 679   GQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFS-PLVATSESVTEITASSFV 737
             G  + I+   H++   +  T  +   P  S TV+ +      P       V+EI   S  
Sbjct: 10899 GSKLEIRNAAHEDGGIYSLTVEN---PAGSKTVSVKVLVLDKPGPPRDLEVSEIRKDSCY 10955

Query: 738   VSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVN----IPDLLPGRKYIVNVYQI 793
             ++W    D        Y + E  D       P +ATS         L  G +Y+  V   
Sbjct: 10956 LTWKEPLDDGGSVITNYVV-ERRDVASAQWSPLSATSKKKSHFAKHLNEGNQYLFRVAAE 11014

Query: 794   SEDGEQSLILSTSQTTAPDA--PPDPTVD----QVDDTSIVVRWSRPQ----APITGYRI 843
             ++ G    + +     A D   PP P  D     VD T + + W++P     +PITGY +
Sbjct: 11015 NQYGRGPFVETPKPIKALDPLHPPGPPKDLHHVDVDKTEVSLVWNKPDRDGGSPITGYLV 11074

Query: 844   VYSPSVEGSSTELNLPETAN-SVTLSDLQPGVQYNITIYA---VEENQESTPVVIQQETT 899
              Y    EG+   +      N    ++ LQ G  Y   + A   V      T + I+ +  
Sbjct: 11075 EYQE--EGTQDWIKFKTVTNLECVVTGLQQGKTYRFRVKAENIVGLGLPDTTIPIECQEK 11132

Query: 900   GTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEH---GQRLPI 956
               P S  +    D++ +E   VK       P + + G  V        G      +   +
Sbjct: 11133 LVPPSVEL----DVKLIEGLVVKAGTTVRFP-AIIRGVPVPTAKWTTDGSEIKTDEHYTV 11187

Query: 957   SRNTFAEVTGLSPGV---TYYFKVFAVSHGRESKPLTAQQTTKLDAPTN----LQFVNET 1009
               + F+ V  +   +   T  +++  VS+   SK + A   T LD P      +  ++ T
Sbjct: 11188 ETDNFSSVLTIKNCLRRDTGEYQI-TVSNAAGSKTV-AVHLTVLDVPGPPTGPINILDVT 11245

Query: 1010  DSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVS 1065
                + + W PP+    + +  Y +    TR+      + G S +K  + +LQ   EY   
Sbjct: 11246 PEHMTISWQPPKDDGGSPVINYIVEKQDTRKDTWGVVSSGSSKTKLKIPHLQKGCEYVFR 11305

Query: 1066  LVAIKGNQESPKATGVFTTLQPGSSIP-----PYNTEVTETTIVITWT------PAPRIG 1114
             + A       P      T  +   S P     P  T++TE    ++WT       +P  G
Sbjct: 11306 VRAENKIGVGPPLDSTPTVAKHKFSPPSPPGKPVVTDITENAATVSWTLPKSDGGSPITG 11365

Query: 1115  FKLGVRPSQGGEAPREVTSDSG-SIVVSGLTPGVEYVYTIQVLR-DGQERDAPIVNKV-- 1170
             + +  R   G       T  +     V+GL  G  Y + +      G  + +P  + +  
Sbjct: 11366 YYMERREVTGKWVRVNKTPIADLKFRVTGLYEGNTYEFRVFAENLAGLSKPSPSSDPIKA 11425

Query: 1171  ---VTPLSPPTNLHLEANPDTGVLTVSWERSTTPD---ITGYRITTTPTNGQQGNSLEEV 1224
                + P  PP N  L+ +       + W +  +     I GY +        Q N + + 
Sbjct: 11426 CRPIKPPGPPINPKLK-DKSRETADLVWTKPLSDGGSPILGYVVECQKPGTAQWNRINKD 11484

Query: 1225  VHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVP--ISDTIIPAV---PPPTDLRFTNIG 1279
                 Q +     L  G EY   +       E  P  +++++I      PP  +L  T   
Sbjct: 11485 ELIRQCAFRVPGLIEGNEYRFRIKAANIVGEGEPRELAESVIAKDILHPPEVELDVTCRD 11544

Query: 1280  PDTMRVTWA----------PPPSIDLTN---FLVRYSPVKNEEDV--AELSISPSDNAVV 1324
               T+RV             P P I  T     LVR   V   +D+   EL I  +  A  
Sbjct: 11545 VITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRA-- 11602

Query: 1325  LTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSP---TGIDFSDITANSFTVHWIAP 1381
                     +Y++S  +     + + +       LD P     +  +++T  + T+ W  P
Sbjct: 11603 -----DHGKYIISAKNSSGHAQGSAI----VNVLDRPGPCQNLKVTNVTKENCTISWENP 11653

Query: 1382  R----ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNG---- 1433
                  + IT + + +   +  G          R  +   NL    EY   + A N     
Sbjct: 11654 LDNGGSEITNFIVEYRKPNQKGWSIVASDVTKR--LIKANLLANNEYYFRVCAENKVGVG 11711

Query: 1434  ---REESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYG---ETGG 1487
                  ++P+L          P +L +     T + + W  P        ++Y       G
Sbjct: 11712 PTIETKTPILAINPIDRPGEPENLHIADKGKTFVYLKWRRPDYDGGSPNLSYHVERRLKG 11771

Query: 1488  NSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASS--KPISINYRTEIDKP 1545
             +   +       K T  +  +   V+  I  + V  + +   S   K   +  + ++ KP
Sbjct: 11772 SDDWERVHKGSIKETHYM--VDRCVENQIYEFRVQTKNEGGESDWVKTEEVVVKEDLQKP 11829

Query: 1546  SQMQVTDVQDNSIS-VKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMT------ 1598
                    V D  +S V  + +   +   R+    +  P P    T   D T++T      
Sbjct: 11830 -------VLDLKLSGVLTVKAGDTI---RLEAGVRGKPFPEVAWTKDKDATDLTRSPRVK 11879

Query: 1599  IEGLQPTVEYVVSVYAQNPSGE--------SQPLVQTAVTNI-DRP---KGLAFTDVDVD 1646
             I+    + ++ ++   ++  G+        +   V  A  N+ D+P   + L   DV  D
Sbjct: 11880 IDTRADSSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATVNVLDKPGPVRNLKIVDVSSD 11939

Query: 1647  SIKIAWESPQG----QVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSV 1702
                + W+ P+     ++  Y +     +  +   + A      T   + L  G+EY   V
Sbjct: 11940 RCTVCWDPPEDDGGCEIQNYILEKCETKRMVWSTYSATVLTPGTTVTR-LIEGNEYIFRV 11998

Query: 1703  -----VALHDDMESQPLIGTQSTAIPA-PTDLKFTQVTPTSLSAQWTPPNVQ----LTGY 1752
                  +      ES+P+I       P  P   + T+V+   ++  W PP       +TGY
Sbjct: 11999 RAENKIGTGPPTESKPVIAKTKYDKPGRPDPPEVTKVSKEEMTVVWNPPEYDGGKSITGY 12058

Query: 1753  RVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKD------TLTSRPAQG 1806
              +    K  T  +     A     + V  L+   +Y+  V A  +      +L SRP   
Sbjct: 12059 FLEKKEKHSTRWVPVNKSAIPERRMKVQNLLPDHEYQFRVKAENEIGIGEPSLPSRPVVA 12118

Query: 1807  VVTTLENVSPPRRARVTDATETTITISWRTKT----ETITGFQV-------DAVPANGQT 1855
                 +E   PP   RV D T+ +IT+ W          I G+ V       DA P  G  
Sbjct: 12119 K-DPIEPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAPIIGYVVEMRPKIADASPDEGWK 12177

Query: 1856  PIQRTIKPDVRSYTITGLQPGTDYKIYLYTLN 1887
                   +   + +T+T L    +Y+  +   N
Sbjct: 12178 RCNAAAQLVRKEFTVTSLDENQEYEFRVCAQN 12209



 Score = 75.9 bits (185), Expect = 4e-13
 Identities = 162/749 (21%), Positives = 272/749 (36%), Gaps = 110/749 (14%)

Query: 1233  TFDNLSPGLEYNVSVYTVKDDKESVPIS-----DTIIPAVPPPTDLRF-------TNI-- 1278
             T ++L  G EY   V  V     S P +     D   P +PP  DL+        TN+  
Sbjct: 9705  TVEDLVEGGEYEFRVKAVNAAGVSKPSATVGPCDCQRPDMPPSIDLKEFMEVEEGTNVNI 9764

Query: 1279  -----GPDTMRVTW--APPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPG 1331
                  G     +TW  APP   D         PV  +  V +L +  +   V+  +    
Sbjct: 9765  VAKIKGVPFPTLTWFKAPPKKPD------NKEPVLYDTHVNKLVVDDTCTLVIPQSRRSD 9818

Query: 1332  TEY--VVSVSSVYEQHESTPLRGRQKTGLDSPTG-IDFSDITANSFTVHWIAPR----AT 1384
             T    + +V+++    +   L    + G   P G I F  ++A+  T+ W  P+    + 
Sbjct: 9819  TGLYTITAVNNLGTASKEMRLNVLGRPG--PPVGPIKFESVSADQMTLSWFPPKDDGGSK 9876

Query: 1385  ITGYRIRHHPE------HFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGR---- 1434
             IT Y I           H S  P+E        + T+  L  G EYV  I+A N      
Sbjct: 9877  ITNYVIEKREANRKTWVHVSSEPKEC-------TYTIPKLLEGHEYVFRIMAQNKYGIGE 9929

Query: 1435  --EESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVT----VRYYRITYGETGGN 1488
               +  P       +V   P    V + T  S+ ++W+ P       V  Y +   +T   
Sbjct: 9930  PLDSEPETARNLFSVPGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPVTGYWLEMKDTTSK 9989

Query: 1489  -------SPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPAS--SKPISINYR 1539
                     P++  T+  S     ++GL  G DY   VYA+   G  PAS  S P +    
Sbjct: 9990  RWKRVNRDPIKAMTLGVSYK---VTGLIEGSDYQFRVYAINAAGVGPASLPSDPATARDP 10046

Query: 1540  TEIDKPSQMQVTDVQDNSISVKWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQT 1595
                  P   +VTD   +S  ++W P      S VTGY V    +      K K      T
Sbjct: 10047 IAPPGPPFPKVTDWTKSSADLEWSPPLKDGGSKVTGYIVEYKEEGKEEWEKGKDKEVRGT 10106

Query: 1596  EMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVD-SIKIAWES 1654
             ++ + GL+    Y   V A N +G  +P   T V  I+    L   D+ +D S++     
Sbjct: 10107 KLVVTGLKEGAFYKFRVRAVNIAGIGEPGEVTDV--IEMKDRLVSPDLQLDASVRDRIVV 10164

Query: 1655  PQGQVSRY----------RVTYSSPEDGI-HELFPAPDGEEDTAELQGLRPGSEYTVSVV 1703
               G V R            VT++  E  +  E          +  ++  +   +   S++
Sbjct: 10165 HAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEATIETTAISSSMVIKNCQRSHQGVYSLL 10224

Query: 1704  ALHDDMESQPLIGTQSTAIPAPTDLKFT--QVTPTSLSAQWTPP----NVQLTGYRVRVT 1757
             A ++  E +  I      +P P    F    +T  S    W  P       +T Y +   
Sbjct: 10225 AKNEAGERKKTIIVDVLDVPGPVGTPFLAHNLTNESCKLTWFSPEDDGGSPITNYVIEKR 10284

Query: 1758  PKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRP---AQGVVTTLENV 1814
               ++      +       +  V GL+    Y   + A ++++   P       +   E +
Sbjct: 10285 ESDRRA-WTPVTYTVTRQNATVQGLIQGKAYFFRI-AAENSIGMGPFVETSEALVIREPI 10342

Query: 1815  SPPRR---ARVTDATETTITISWRTKT----ETITGFQVDAVPANGQTPIQRTIKPDV-- 1865
             + P R     V + T+ T+T++W          I  + +++    G     +    ++  
Sbjct: 10343 TVPERPEDLEVKEVTKNTVTLTWNPPKYDGGSEIINYVLES-RLIGTEKFHKVTNDNLLS 10401

Query: 1866  RSYTITGLQPGTDYKIYLYTLNDNARSSP 1894
             R YT+ GL+ G  Y+  +  +N   +  P
Sbjct: 10402 RKYTVKGLKEGDTYEYRVSAVNIVGQGKP 10430



 Score = 74.3 bits (181), Expect = 1e-12
 Identities = 171/843 (20%), Positives = 321/843 (38%), Gaps = 99/843 (11%)

Query: 1141  SGLTPGVEYVYTIQVLRDG----QERDAPIV---NKVVTPLSPPTNLHLEANPDTGVLTV 1193
             +GL  G EY Y +              +P++   + V  P SPP+   +  +  T  +T+
Sbjct: 19673 TGLREGCEYEYRVYAENAAGLSLPSETSPLIRAEDPVFLP-SPPSKPKIVDSGKT-TITI 19730

Query: 1194  SWERSTTPD---ITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTV 1250
             +W +        ITGY +    ++     +  + +   +   T   L+ G EY   V +V
Sbjct: 19731 AWVKPLFDGGAPITGYTVEYKKSDDTDWKTSIQSLRGTEY--TISGLTTGAEYVFRVKSV 19788

Query: 1251  KDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFL-VRYSPVKN-- 1307
                  S P SD+  P +    +          MR T         T  +  R  PV N  
Sbjct: 19789 NKVGASDP-SDSSDPQIAKEREEEPLFDIDSEMRKTLIVKAGASFTMTVPFRGRPVPNVL 19847

Query: 1308  ----EEDVAELS-ISPSDNAVVLT----NLLPGTEYVVSVSSVYEQHESTPLRGRQKTGL 1358
                 + D+   + +  +D+   LT    N     +Y +++ +V      T +     T  
Sbjct: 19848 WSKPDTDLRTRAYVDTTDSRTSLTIENANRNDSGKYTLTIQNVLSAASLTLVVKVLDTP- 19906

Query: 1359  DSPTGIDFSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRNSIT 1414
               PT I   D+T  S  + W  P     A +  Y I       + +     V ++ N ++
Sbjct: 19907 GPPTNITVQDVTKESAVLSWDVPENDGGAPVKNYHIEKRE---ASKKAWVSVTNNCNRLS 19963

Query: 1415  --LTNLTPGTEYVVSIVALNGREESPLLIGQQSTVS-------DVPRDLEVVAATPTSLL 1465
               +TNL  G  Y   +   +G  E  + I  ++            P  L V + +  S+ 
Sbjct: 19964 YKVTNLQEGAIYYFRV---SGENEFGVGIPAETKEGVKITEKPSPPEKLGVTSISKDSVS 20020

Query: 1466  ISWDAP----AVTVRYYRITYGETGGNSPVQEFTVPGSKSTA-TISGLKPGVDYTITVYA 1520
             ++W  P       + +Y +   E G  + V+      +KST   +SGL+   +Y   V+A
Sbjct: 20021 LTWLKPEHDGGSRIVHYVVEALEKGQKNWVK---CAVAKSTHHVVSGLRENSEYFFRVFA 20077

Query: 1521  VTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKW---LPSSSPVTGYRVTTT 1577
                 G S      + +  + +++ P ++ + +   +++ V+    L    P++G  +   
Sbjct: 20078 ENQAGLSDPRELLLPVLIKEQLEPP-EIDMKNFPSHTVYVRAGSNLKVDIPISGKPLPKV 20136

Query: 1578  PKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVS-------VYAQNPSGESQPLVQTAVT 1630
               +  G    K      TE+T E L   ++  V+       + A N SG ++  +   V 
Sbjct: 20137 TLSRDG-VPLKATMRFNTEITAENLTINLKESVTADAGRYEITAANSSGTTKAFINIVV- 20194

Query: 1631  NIDRPKG----LAFTDVDVDSIKIAWESPQ----GQVSRYRVTYSSPEDGIHELFPAPDG 1682
              +DRP      +  +D+  +S+ + WE P+     QV+ Y +        +     A   
Sbjct: 20195 -LDRPGPPTGPVVISDITEESVTLKWEPPKYDGGSQVTNYILLKRETSTAVWTEVSATVA 20253

Query: 1683  EEDTAELQGLRPGSEYTVSVVA-----LHDDMESQPLIGTQSTAIPAPTDLKF-TQVTPT 1736
                  ++  L  G EY   + A     + D ++S  +        P P    + T VT  
Sbjct: 20254 RT-MMKVMKLTTGEEYQFRIKAENRFGISDHIDSACVTVKLPYTTPGPPSTPWVTNVTRE 20312

Query: 1737  SLSAQWTPP----NVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSV 1792
             S++  W  P       + GY + +  +      K   L   ++   V+ +     YE  V
Sbjct: 20313 SITVGWHEPVSNGGSAVVGYHLEMKDRNSILWQKANKLVIRTTHFKVTTISAGLIYEFRV 20372

Query: 1793  YALKDTLTSRPAQGV--VTTLENVSPPRRARVTDATETTITISWRTKT----ETITGFQV 1846
             YA       +P+     V  ++   PPR  R+TD ++ ++++SW+         ITG+ V
Sbjct: 20373 YAENAAGVGKPSHPSEPVLAIDACEPPRNVRITDISKNSVSLSWQQPAFDGGSKITGYIV 20432

Query: 1847  DA--VPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLN--DNARSSPVVIDASTA 1902
             +   +P    T    T   + + + I+GL   + Y+  ++  N   +  +   V+   T 
Sbjct: 20433 ERRDLPDGRWTKASFTNVTETQ-FIISGLTQNSQYEFRVFARNAVGSISNPSEVVGPITC 20491

Query: 1903  IDA 1905
             ID+
Sbjct: 20492 IDS 20494



 Score = 65.5 bits (158), Expect = 6e-10
 Identities = 290/1521 (19%), Positives = 542/1521 (35%), Gaps = 205/1521 (13%)

Query: 628   IQWNAPQ---PSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISI 684
             + W+AP     S ++ + +  + +NS+   K  T P     Y   GL  G+ Y+ ++ + 
Sbjct: 21403 LTWDAPVYDGGSEVTGFHVEKKERNSILWQKVNTSPISGREYRATGLVEGLDYQFRVYAE 21462

Query: 685   QQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSAS 744
                G              S+P   +  T   +P  P    +    ++T  +  + W    
Sbjct: 21463 NSAG-------------LSSPSDPSKFTLAVSPVDP--PGTPDYIDVTRETITLKWNPPL 21507

Query: 745   DTVSGFRVEYELSEEGDEPQYLDLPSTATS---VNIPDLLPGRKYIVNVYQ------ISE 795
                    V Y + +     +++    T  S     +  L PG +Y   +        IS 
Sbjct: 21508 RDGGSKIVGYSIEKRQGNERWVRCNFTDVSECQYTVTGLSPGDRYEFRIIARNAVGTISP 21567

Query: 796   DGEQSLILSTSQTTAPDAPPDPTVD---QVDDTSIVVRWS--RPQAPITGYRIV----YS 846
               + S I+ T     P     P V+   +  D  I+      R +A + G  +     + 
Sbjct: 21568 PSQSSGIIMTRDENVP-----PIVEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVTWFK 21622

Query: 847   PSVE-GSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQES--TPVVIQQETTGTPR 903
               VE      + + +   S +L  ++   + +  +Y VE    S      I+ +   TP 
Sbjct: 21623 DGVEIEKRMNMEITDVLGSTSLF-VRDATRDHRGVYTVEAKNASGSAKAEIKVKVQDTPG 21681

Query: 904   SDTVPSPRDLQFVEVTDVKVTIMWTPPES----AVTGYRVDVIPVNLPGEHGQRLPISRN 959
                 P    ++F  +T  K+T+ W  P +     +T Y ++    +              
Sbjct: 21682 KVVGP----IRFTNITGEKMTLWWDAPLNDGCAPITHYIIEKRETSRLAWALIEDKCEAQ 21737

Query: 960   TFAEVTGLSPGVTYYFKVFAVSH---GR--ESKPLTAQ-QTTKLDAPTNLQFVNETDSTV 1013
             ++  +  L  G  Y F+V AV+    GR  +S P+ AQ Q T  DAP   +  N T +++
Sbjct: 21738 SYTAIK-LINGNEYQFRVSAVNKFGVGRPLDSDPVVAQIQYTVPDAPGIPEPSNITGNSI 21796

Query: 1014  LVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRN-------LQPASEYTVSL 1066
              + W  P +   G  +   +  R + +       +SK P+         L   +EY   +
Sbjct: 21797 TLTWARPESD-GGSEIQQYILERREKKSTRWVKVISKRPISETRFKVTGLTEGNEYEFHV 21855

Query: 1067  VAIKGNQESPKATGVFTTLQ-------PGSSIPPYNTEVTETTIVITWTPA------PRI 1113
             +A       P A+G+   ++       PG       T+ ++TT+ + W+          I
Sbjct: 21856 MAENAAGVGP-ASGISRLIKCREPVNPPGPPTVVKVTDTSKTTVSLEWSKPVFDGGMEII 21914

Query: 1114  GFKLGVRPSQGGEAPREVTSDS---GSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKV 1170
             G+ + +  +  G+   +V +++       V+ L  G EY + +  +    + D+  V   
Sbjct: 21915 GYIIEMCKADLGDW-HKVNAEACVKTRYTVTDLQAGEEYKFRVSAINGAGKGDSCEVTGT 21973

Query: 1171  VTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPT----NGQQGNSLEEVVH 1226
             +  +   T   L+ + +     V    ++      Y+   TPT          SL   +H
Sbjct: 21974 IKAVDRLTAPELDIDANFKQTHVVRAGASIRLFIAYQGRPTPTAVWSKPDSNLSLRADIH 22033

Query: 1227  ADQSSCTFD----NLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRFTNIGPDT 1282
                S  T      N +   +Y ++V      K S+  +  ++    PP  + F ++   +
Sbjct: 22034 TTDSFSTLTVENCNRNDAGKYTLTVENNSGSK-SITFTVKVLDTPGPPGPITFKDVTRGS 22092

Query: 1283  MRVTWAPPPSIDLTNFLVRYSPVKNEEDVAE---LSISPSDNAVVLTNLLPGTEYVVSVS 1339
               + W   P +D    +  Y   K E        +S   +     + +L  G  Y   VS
Sbjct: 22093 ATLMW-DAPLLDGGARIHHYVVEKREASRRSWQVISEKCTRQIFKVNDLAEGVPYYFRVS 22151

Query: 1340  SVYEQHESTPLRGRQKTGLDS----PTGIDFSDITANSFTVHWIAPR----ATITGYRIR 1391
             +V E     P    +          P  +D  D + +S  + W+ P     + ITGY + 
Sbjct: 22152 AVNEYGVGEPYEMPEPIVATEQPAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRITGYLLE 22211

Query: 1392  HHPEHFSGRPREDRVPHSRN-SITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDV 1450
                +   G        H++  + T+  L   TEY   + A N    S       S +   
Sbjct: 22212 MRQK---GSDFWVEAGHTKQLTFTVERLVEKTEYEFRVKAKNDAGYSEPREAFSSVIIKE 22268

Query: 1451  PR-----DLEVV--------AATPTSL---LISWDAPAVTVRYYRITYGETGGNSPVQEF 1494
             P+     DL  +        A +P ++   +    AP VT +   +   ET   S     
Sbjct: 22269 PQIEPTADLTGITNQLITCKAGSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVS----I 22324

Query: 1495  TVPGSKSTATISGLKPGVD--YTITVYAVTGRGDSPASSKPISINYRTEIDKPSQM---- 1548
             T    ++T T+     G    Y +T+       ++ A  K  S+     I +P  +    
Sbjct: 22325 TTTKDRTTLTVKDSMRGDSGRYFLTL-------ENTAGVKTFSVTV-VVIGRPGPVTGPI 22376

Query: 1549  QVTDVQDNSISVKWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQP 1604
             +V+ V   S  + W        + +T Y +    ++G    +   +   +T++ +  L  
Sbjct: 22377 EVSSVSAESCVLSWGEPKDGGGTEITNY-IVEKRESGTTAWQLVNSSVKRTQIKVTHLTK 22435

Query: 1605  TVEYVVSVYAQNPSGESQPLVQTAV------TNIDRPKGLAFTDVDVDSIKIAWESPQGQ 1658
              +EY   V ++N  G S+PL    +           P       V  +++ I WE P   
Sbjct: 22436 YMEYSFRVSSENRFGVSKPLESAPIIAEHPFVPPSAPTRPEVYHVSANAMSIRWEEPYHD 22495

Query: 1659  VSRYRVTYSSPEDGIHELFPAPDGE----EDTAELQGLRPGSEYTVSVVALH------DD 1708
                  + Y   +   + +    + +    E   ++ GL  G EY     AL+        
Sbjct: 22496 GGSKIIGYWVEKKERNTILWVKENKVPCLECNYKVTGLVEGLEYQFRTYALNAAGVSKAS 22555

Query: 1709  MESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPP----NVQLTGYRVRVTPKEKTGP 1764
               S+P++      + AP   + T VT +++S  W+ P      ++ GY +   P  + G 
Sbjct: 22556 EASRPIMA--QNPVDAPGRPEVTDVTRSTVSLIWSAPAYDGGSKVVGYIIERKPVSEVGD 22613

Query: 1765  ---MKEINLAPDSSSVVVSGLMVATKYEVSVYALKDT-LTSRPAQ--GVVTTLENVSPPR 1818
                +K        +   V+ L     YE  V A     + S+ ++  G VT  +  +PP+
Sbjct: 22614 GRWLKCNYTIVSDNFFTVTALSEGDTYEFRVLAKNAAGVISKGSESTGPVTCRDEYAPPK 22673

Query: 1819  RARVTDATETTITISWRTKTETITGFQVDAVP------ANGQTPIQRTIKPDV-----RS 1867
                  DA      ++ R  ++ +    V   P        G   +    K  +     R+
Sbjct: 22674 AE--LDARLHGDLVTIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRA 22731

Query: 1868  YTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAP---SNLRFLATTPNSLLVSWQ 1924
               +      +D   Y  T+  NA  +  V      +D+P     L     T     ++W 
Sbjct: 22732 TAVIKFCDRSDSGKYTLTVK-NASGTKAVSVMVKVLDSPGPCGKLTVSRVTQEKCTLAWS 22790

Query: 1925  PPR----ARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKN-- 1978
              P+    A IT YI++  +       +V    P ++   +T L    EY   V A+    
Sbjct: 22791 LPQEDGGAEITHYIVERRETSRLNWVIVEGECPTLS-YVVTRLIKNNEYIFRVRAVNKYG 22849

Query: 1979  ---NQKSEPLIGRKKTVQKTP 1996
                  +SEP++ R      +P
Sbjct: 22850 PGVPVESEPIVARNSFTIPSP 22870



 Score = 64.3 bits (155), Expect = 1e-09
 Identities = 115/519 (22%), Positives = 183/519 (35%), Gaps = 81/519 (15%)

Query: 1542  IDKPS---QMQVTDVQDNSISVKWLPSSSP----VTGYRVTTTP-KNGPGPTKTKTAGPD 1593
             +DKP     +++ DV  +  +V W P        +  Y +     K     T + T    
Sbjct: 11922 LDKPGPVRNLKIVDVSSDRCTVCWDPPEDDGGCEIQNYILEKCETKRMVWSTYSATVLTP 11981

Query: 1594  QTEMT--IEGLQPTVEYVVSVYAQN-----PSGESQPLV-QTAVTNIDRPKGLAFTDVDV 1645
              T +T  IEG     EY+  V A+N     P  ES+P++ +T      RP     T V  
Sbjct: 11982 GTTVTRLIEGN----EYIFRVRAENKIGTGPPTESKPVIAKTKYDKPGRPDPPEVTKVSK 12037

Query: 1646  DSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGE----EDTAELQGLRPGSEYTVS 1701
             + + + W  P+    +    Y   +   H     P  +    E   ++Q L P  EY   
Sbjct: 12038 EEMTVVWNPPEYDGGKSITGYFLEKKEKHSTRWVPVNKSAIPERRMKVQNLLPDHEYQFR 12097

Query: 1702  VVALHD------DMESQPLIGTQSTAIPAP-TDLKFTQVTPTSLSAQWTPP----NVQLT 1750
             V A ++       + S+P++       P P T+ +    T  S++  W  P       + 
Sbjct: 12098 VKAENEIGIGEPSLPSRPVVAKDPIEPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAPII 12157

Query: 1751  GYRVRVTPKEKTGP----MKEINLAPD--SSSVVVSGLMVATKYEVSVYALKDTLTSRPA 1804
             GY V + PK          K  N A         V+ L    +YE  V A       RPA
Sbjct: 12158 GYVVEMRPKIADASPDEGWKRCNAAAQLVRKEFTVTSLDENQEYEFRVCAQNQVGIGRPA 12217

Query: 1805  Q--GVVTTLENVSPPRRARVTDATETTIT-------------------ISWRTK--TETI 1841
             +    +   E + PP         +  I                    ++WR       +
Sbjct: 12218 ELKEAIKPKEILEPPEIDLDASMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVV 12277

Query: 1842  TGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDAST 1901
                QVD V       I  + + D   Y++T + P  +  +++     N R    V+D   
Sbjct: 12278 RKGQVDLVDTMAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFV-----NVR----VLDTPG 12328

Query: 1902  AIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREVVPRPRPGVTE 1957
              +   S+L+    T  S  VSW PP     +++T YI++  +        V  P    T 
Sbjct: 12329 PV---SDLKVSDVTKTSCHVSWAPPENDGGSQVTHYIVEKREADRKTWSTVT-PEVKKTS 12384

Query: 1958  ATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQKTP 1996
               +T L PG EY   V A+       P    K  +   P
Sbjct: 12385 FHVTNLVPGNEYYFRVTAVNEYGPGVPTDVPKPVLASDP 12423



 Score = 62.4 bits (150), Expect = 5e-09
 Identities = 182/847 (21%), Positives = 298/847 (35%), Gaps = 156/847 (18%)

Query: 1263 IIPAVPPPTDLRFTNIGPDTMRVTWAPPPS---IDLTNFLVRYSPVKNEEDVAELSISPS 1319
            +I    P  +L  T      + + W  P +     +  ++V    +K +  V     + S
Sbjct: 6714 VIDVPGPVRNLEVTETFDGEVSLAWEEPLTDGGSKIIGYVVERRDIKRKTWVLATDRAES 6773

Query: 1320 DNAVVLTNLLPGTEYVVSVSS-----VYEQHES-TPLRGRQKTGLDSPT-GIDFSDITAN 1372
                V      G EY+  VS+       E  E+  P+  R K  +  P   +  +D+   
Sbjct: 6774 CEFTVTGLQKGGVEYLFRVSARNRVGTGEPVETDNPVEARSKYDVPGPPLNVTITDVNRF 6833

Query: 1373 SFTVHWIAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSI 1428
              ++ W  P     A IT Y I    +          V     S T+T++  G EY   +
Sbjct: 6834 GVSLTWEPPEYDGGAEITNYVIELRDKTSIRWDTAMTVRAEDLSATVTDVVEGQEYSFRV 6893

Query: 1429 VALNGREESPLLIGQQSTVSDV------------PRDLEVVAATPTSLLISWDAP----A 1472
                 R ++ + +G+ S  +              P +L     T +S+ + W+ P     
Sbjct: 6894 -----RAQNRIGVGKPSAATPFVKVADPIERPSPPVNLTSSDQTQSSVQLKWEPPLKDGG 6948

Query: 1473 VTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSK 1532
              +  Y I   E G ++ ++       + T  ++GL+ G  Y   V A    G S  S  
Sbjct: 6949 SPILGYIIERCEEGKDNWIRCNMKLVPELTYKVTGLEKGNKYLYRVSAENKAGVSDPSEI 7008

Query: 1533 PISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSS--PVTGYRVTTTPKNGPGPTKTKTA 1590
               +       +P+ M ++  +D    +   P +   P TGY         P PT T   
Sbjct: 7009 LGPLTADDAFVEPT-MDLSAFKDGLEVIVPNPITILVPSTGY---------PRPTATWCF 7058

Query: 1591 GPDQTE----MTIEGLQPTVEYVVSVYAQNPSG----ESQPLVQTAVTNID--------R 1634
            G    E    + ++ L    E V+S   ++  G    + +  V+T    ID         
Sbjct: 7059 GDKVLETGDRVKMKTLSAYAELVISPSERSDKGIYTLKLENRVKTISGEIDVNVIARPSA 7118

Query: 1635 PKGLAFTDVDVDSIKIAWESPQ----GQVSRY--------RVTYSSPEDGIHEL-FPAPD 1681
            PK L F D+  DS+ + WE P       ++ Y        R T++   D + +L F  PD
Sbjct: 7119 PKELKFGDITKDSVHLTWEPPDDDGGSPLTGYVVEKREVSRKTWTKVMDFVTDLEFTVPD 7178

Query: 1682 GEEDTAELQGLRPGSEYTVSVVALHDDMESQPL-------IGTQSTAIPAPTDLKFTQVT 1734
                      L  G EY   V A +     +P        + T +T    P ++K+   T
Sbjct: 7179 ----------LVQGKEYLFKVCARNKCGPGEPAYVDEPVNMSTPATVPDPPENVKWRDRT 7228

Query: 1735 PTSLSAQWTPP----NVQLTGYRVRVTPKEKTGPMKEINLAPD--SSSVVVSGLMVATKY 1788
              S+   W PP      ++ GY V   P+   G  K +        + + V+GL     Y
Sbjct: 7229 ANSIFLTWDPPKNDGGSRIKGYIVERCPR---GSDKWVACGEPVAETKMEVTGLEEGKWY 7285

Query: 1789 EVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETT-----------ITISWRTK 1837
               V AL     S+P++          P    +  D  E             +T+   TK
Sbjct: 7286 AYRVKALNRQGASKPSR----------PTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTK 7335

Query: 1838 TE---TITGFQVDAVPANGQTPIQRTIKPDVR----------SYTITGLQPGTDYKIYLY 1884
             E   T+TG      P    T     +K D R          + TI   +        + 
Sbjct: 7336 IELPATVTG---KPEPKITWTKADMILKQDKRITIENVPKKSTVTIVDSKRSDTGTYIIE 7392

Query: 1885 TLNDNARSSPVV-IDASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEK 1939
             +N   R++ VV ++       P+       T  S L++W PPR    ++IT Y+++   
Sbjct: 7393 AVNVCGRATAVVEVNVLDKPGPPAAFDITDVTNESCLLTWNPPRDDGGSKITNYVVERRA 7452

Query: 1940 PGSPPREVVPRPRPGV--TEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQKTPF 1997
              S   EV  +    V  T    T L P  EY   V A       E + G  + VQ +P 
Sbjct: 7453 TDS---EVWHKLSSTVKDTNFKATKLIPNKEYIFRVAA-------ENMYGVGEPVQASPI 7502

Query: 1998 VTHPGYD 2004
                 +D
Sbjct: 7503 TAKYQFD 7509



 Score = 52.8 bits (125), Expect = 4e-06
 Identities = 80/336 (23%), Positives = 120/336 (35%), Gaps = 46/336 (13%)

Query: 602  LQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQP---SHISKYILRWRPKN-SVGRWKEA 657
            ++ Y   S P  + +T+  ++  S  + W+AP     S I+ Y++  R  +     W+E 
Sbjct: 9120 VEVYDRPSPPRNLAVTDIKAE--SCYLTWDAPLDNGGSEITHYVIDKRDASRKKAEWEEV 9177

Query: 658  TIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTP 717
            T       Y I  L P   YE ++ ++ +YG  +  + D         V  +       P
Sbjct: 9178 TNTAVEKRYGIWKLIPNGQYEFRVRAVNKYGISDECKSD-------KVVIQDPYRLPGPP 9230

Query: 718  FSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTA----- 772
              P V         T  S +VSW    D        Y L +  +   Y    S A     
Sbjct: 9231 GKPKVLAR------TKGSMLVSWTPPLDNGGSPITGYWLEKREEGSPYWSRVSRAPITKV 9284

Query: 773  ----TSVNIPDLLPGRKY-----IVNVYQISEDGEQSLILSTSQTTAPDAPPD-PTVDQV 822
                   N+P LL G KY      +N   I    E S          P  PP  P V   
Sbjct: 9285 GLKGVEFNVPRLLEGVKYQFRAMAINAAGIGPPSEPSDPEVAGDPIFPPGPPSCPEVKDK 9344

Query: 823  DDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPE---TANSVTLSDLQPGVQ 875
              +SI + W  P     +PI GY +            +N P+   T     + +L+   +
Sbjct: 9345 TKSSISLGWKPPAKDGGSPIKGYIVEMQEEGTTDWKRVNEPDKLITTCECVVPNLKELRK 9404

Query: 876  YNITIYAVEENQESTPVVIQQETTG-TPRSDTVPSP 910
            Y   + AV E  ES P     +TTG  P +D    P
Sbjct: 9405 YRFRVKAVNEAGESEP----SDTTGEIPATDIQEEP 9436



 Score = 43.9 bits (102), Expect = 0.002
 Identities = 50/204 (24%), Positives = 83/204 (40%), Gaps = 22/204 (10%)

Query: 717   PFSPLVATSESVTEITASSFVVSWVSASDT----VSGFRVEYELSEEGDEPQYLDLPSTA 772
             P  P+V     +  +  +S V+SW   +D     ++ + VE   ++EG E Q +    + 
Sbjct: 24354 PTGPIV-----IEALLKNSAVISWKPPADDGGSWITNYVVEKCEAKEGAEWQLVSSAISV 24408

Query: 773   TSVNIPDLLPGRKYIV-----NVYQISEDGE-QSLILSTSQTTAPDAPPDPTVDQVDDTS 826
             T+  I +L     Y       N + IS+  E  S+++  S    P AP  PT+  V   S
Sbjct: 24409 TTCRIVNLTENAGYYFRVSAQNTFGISDPLEVSSVVIIKSPFEKPGAPGKPTITAVTKDS 24468

Query: 827   IVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSV-TLSDLQPGVQYNITIY 881
              VV W  P     A I  Y +      +     +   E   +V ++ +L  G++Y   + 
Sbjct: 24469 CVVAWKPPASDGGAKIRNYYLEKREKKQNKWISVTTEEIRETVFSVKNLIEGLEYEFRVK 24528

Query: 882   AVEENQESTPVVIQQETTGTPRSD 905
                   ES    I +    TP+SD
Sbjct: 24529 CENLGGESEWSEISEPI--TPKSD 24550



 Score = 41.2 bits (95), Expect = 0.012
 Identities = 92/413 (22%), Positives = 157/413 (38%), Gaps = 51/413 (12%)

Query: 1285  VTWAPPPSID---LTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSV 1341
             ++W PP       +TN++V     K   +   +S + S     + NL     Y   VS+ 
Sbjct: 24370 ISWKPPADDGGSWITNYVVEKCEAKEGAEWQLVSSAISVTTCRIVNLTENAGYYFRVSAQ 24429

Query: 1342  YEQHESTPLRGRQKTGLDSPTGID-------FSDITANSFTVHWIAPRATITGYRIRHHP 1394
                  S PL       + SP            + +T +S  V W  P A+  G +IR++ 
Sbjct: 24430 NTFGISDPLEVSSVVIIKSPFEKPGAPGKPTITAVTKDSCVVAW-KPPASDGGAKIRNYY 24488

Query: 1395  EHFSGRPREDRVPHSRNSITLT-----NLTPGTEYVVSIVA--LNGREESPLLIGQQSTV 1447
                  + +   +  +   I  T     NL  G EY   +    L G  E   +    +  
Sbjct: 24489 LEKREKKQNKWISVTTEEIRETVFSVKNLIEGLEYEFRVKCENLGGESEWSEISEPITPK 24548

Query: 1448  SDVP----------RDLEVVAATPTSLLISWDA-PAVTVRYYRITYGET----GGNSPVQ 1492
             SDVP          R+L V   +  +L+      P   V++YR   G+     G    +Q
Sbjct: 24549 SDVPIQAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYR--QGKEIIADGLKYRIQ 24606

Query: 1493  EFTVPGSKSTATISGLKPGVDYTITVYAV--TGRGDSPASSKPISINYRTEIDKPSQMQ- 1549
             EF   G      I+ +    D   TVY V  T +G S + +  + +    +I  P  ++ 
Sbjct: 24607 EFK--GGYHQLIIASV---TDDDATVYQVRATNQGGSVSGTASLEVEVPAKIHLPKTLEG 24661

Query: 1550  ---VTDVQDNSISVKWLPSSS---PVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQ 1603
                V  ++   +S+K +P S    PV  ++      +  G  +        + +   G++
Sbjct: 24662 MGAVHALRGEVVSIK-IPFSGKPDPVITWQKGQDLIDNNGHYQVIVTRSFTSLVFPNGVE 24720

Query: 1604  PTVEYVVSVYAQNPSGESQPLVQTAVTNI-DRPKGLAFTDVDVDSIKIAWESP 1655
                     V A+N  G  Q  V+  V ++ D P+G+  +DV  DS+ + W  P
Sbjct: 24721 RKDAGFYVVCAKNRFGIDQKTVELDVADVPDPPRGVKVSDVSRDSVNLTWTEP 24773



 Score = 37.7 bits (86), Expect = 0.13
 Identities = 36/131 (27%), Positives = 53/131 (40%), Gaps = 8/131 (6%)

Query: 894   IQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPVNLPGE 949
             I Q+T     +D    PR ++  +V+   V + WT P     S +T Y V+        E
Sbjct: 24737 IDQKTVELDVADVPDPPRGVKVSDVSRDSVNLTWTEPASDGGSKITNYIVEKCATT--AE 24794

Query: 950   HGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQ--TTKLDAPTNLQFVN 1007
                R+  +R T   V  L    +Y F+V A +    SKP    +   TK D    + +  
Sbjct: 24795 RWLRVGQARETRYTVINLFGKTSYQFRVIAENKFGLSKPSEPSEPTITKEDKTRAMNYDE 24854

Query: 1008  ETDSTVLVRWT 1018
             E D T  V  T
Sbjct: 24855 EVDETREVSMT 24865



 Score = 35.0 bits (79), Expect = 0.86
 Identities = 38/169 (22%), Positives = 71/169 (42%), Gaps = 17/169 (10%)

Query: 1519  YAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWL-PSS---SPVTGYRV 1574
             Y V  +       K + ++     D P  ++V+DV  +S+++ W  P+S   S +T Y V
Sbjct: 24727 YVVCAKNRFGIDQKTVELDVADVPDPPRGVKVSDVSRDSVNLTWTEPASDGGSKITNYIV 24786

Query: 1575  TTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPL--VQTAVTNI 1632
                        +   A   +T  T+  L     Y   V A+N  G S+P    +  +T  
Sbjct: 24787 EKCATTAERWLRVGQA--RETRYTVINLFGKTSYQFRVIAENKFGLSKPSEPSEPTITKE 24844

Query: 1633  DRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPD 1681
             D+ + + + D +VD  +        +VS  + ++SS ++   +   A D
Sbjct: 24845 DKTRAMNY-DEEVDETR--------EVSMTKASHSSTKELYEKYMIAED 24884


>gi|110349715 titin isoform N2-B [Homo sapiens]
          Length = 26926

 Score =  154 bits (388), Expect = 1e-36
 Identities = 299/1365 (21%), Positives = 509/1365 (37%), Gaps = 169/1365 (12%)

Query: 590   YGRGIGEWHCQPLQTYPSSSGPVEVFITETPSQPNSHPI-QWNAPQP---SHISKYILRW 645
             YG G+     +P+    S + P    I E       H I QW  P+    + IS Y++  
Sbjct: 22723 YGPGVPV-ESEPIVARNSFTIPSPPGIPEEVGTGKEHIIIQWTKPESDGGNEISNYLVDK 22781

Query: 646   RPKNSVGRWKEATIPGHLNSYTIK--GLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTS 703
             R K S+ RW        +    +K   L  G  Y+ ++ ++   G+ E +          
Sbjct: 22782 REKKSL-RWTRVNKDYVVYDTRLKVTSLMEGCDYQFRVTAVNAAGNSEPSE--------- 22831

Query: 704   TPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELS-EEGDE 762
                 SN ++     ++P   ++  V + T  S  ++W           V Y L  +E D 
Sbjct: 22832 ---ASNFISCREPSYTPGPPSAPRVVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDT 22888

Query: 763   PQYLDLPSTATSVN----IPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPT 818
              Q+  + + AT  N    +PDL  G+KY   V  ++  G      S ++    +    P 
Sbjct: 22889 DQWYRVHTNATIRNTEFTVPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEIPD 22948

Query: 819   VDQVDDT--SIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLP-----ETANSVTLSDLQ 871
             ++  DD   ++ +R       +        P +  S   ++L      +T  S +L  + 
Sbjct: 22949 LELADDLKKTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAIIDTTESYSLLIVD 23008

Query: 872   PGVQYNITIYAVE-ENQE----STPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIM 926
                +Y+   Y +E ENQ     +T +V   +T G       P P  ++  EV+   VTI 
Sbjct: 23009 KVNRYDAGKYTIEAENQSGKKSATVLVKVYDTPG-------PCP-SVKVKEVSRDSVTIT 23060

Query: 927   WTPPE----SAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSH 982
             W  P     + V  Y V+     +          S+ T   ++GL  G  YYF+V   + 
Sbjct: 23061 WEIPTIDGGAPVNNYIVEKREAAMRAFKTVTTKCSK-TLYRISGLVEGTMYYFRVLPENI 23119

Query: 983   GRESKPLTAQQTTKLD----APTNLQFVNETDSTVLVRWTPPR----AQITGYRLTVGLT 1034
                 +P        +      P  L+ V+ T STV + W  P     +++TGY L     
Sbjct: 23120 YGIGEPCETSDAVLVSEVPLVPAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEA--C 23177

Query: 1035  RRGQPRQYNV---GPSVSKYPLRNLQPASEYTVSLVAI--KGNQESPKATGVFTTLQPGS 1089
             + G  R   V    P+V ++ + +L    +Y   + A   KG  E P+ T    T+Q   
Sbjct: 23178 KAGTERWMKVVTLKPTVLEHTVTSLNEGEQYLFRIRAQNEKGVSE-PRETVTAVTVQDLR 23236

Query: 1090  SIPPYNTEV-------------TETTIVITWTPAPRIG-FKLGVRPSQGGEAPREVTSDS 1135
              +P  +                 E  I I   P P    F  G +  +      E  +  
Sbjct: 23237 VLPTIDLSTMPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKV 23296

Query: 1136  GSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSW 1195
               + +   T      YT+++          I   ++    PPT        D   +T+SW
Sbjct: 23297 AKLTIRETTIRDTGEYTLELKNVTGTTSETIKVIILDKPGPPTGPIKIDEIDATSITISW 23356

Query: 1196  ERSTTPD---ITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSV----- 1247
             E         ++GY +     +      + E V   +S+  F  L+ G EY   V     
Sbjct: 23357 EPPELDGGAPLSGYVVEQRDAHRPGWLPVSESV--TRSTFKFTRLTEGNEYVFRVAATNR 23414

Query: 1248  YTVKDDKESVPISDTIIPAVP-PPTDLRFTNIGPDTMRVTWAPPPS---IDLTNFLVRYS 1303
             + +    +S  I       +P PP  L+  ++  D M +TW PP       +T ++V   
Sbjct: 23415 FGIGSYLQSEVIECRSSIRIPGPPETLQIFDVSRDGMTLTWYPPEDDGGSQVTGYIVERK 23474

Query: 1304  PVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLR-GRQKTGLD--- 1359
              V+ +  V    +  +      T L  G EY   V+++  +    P R  +    +D   
Sbjct: 23475 EVRADRWVRVNKVPVTMTRYRSTGLTEGLEYEHRVTAINARGSGKPSRPSKPIVAMDPIA 23534

Query: 1360  ---SPTGIDFSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRNS 1412
                 P     +D T  S ++ W  P     + +TGY I           + +  P     
Sbjct: 23535 PPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTKCNTTPTKIRE 23594

Query: 1413  ITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAAT--PTSLLISWDA 1470
              TLT+L  G EY   ++A N         G     ++VP  ++V      P   L     
Sbjct: 23595 YTLTHLPQGAEYRFRVLACNA--------GGPGEPAEVPGTVKVTEMLEYPDYELDERYQ 23646

Query: 1471  PAVTVRY---YRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDS 1527
               + VR     R+T    G   P+ ++T  G +  +  + +     +T  V     RGDS
Sbjct: 23647 EGIFVRQGGVIRLTIPIKGKPFPICKWTKEG-QDISKRAMIATSETHTELVIKEADRGDS 23705

Query: 1528  ---------PASSKPISINYRTEIDKPSQ----MQVTDVQDNSISVKWLPSS----SPVT 1570
                          K + I  R  I  P+     ++  D+Q  S+ V W P +    + + 
Sbjct: 23706 GTYDLVLENKCGKKAVYIKVRV-IGSPNSPEGPLEYDDIQVRSVRVSWRPPADDGGADIL 23764

Query: 1571  GYRVTT--TPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQ-- 1626
             GY +     PK       ++  G   T + ++GL+  VEY   V A+N  G S+PL    
Sbjct: 23765 GYILERREVPKAAWYTIDSRVRG---TSLVVKGLKENVEYHFRVSAENQFGISKPLKSEE 23821

Query: 1627  --TAVTNIDRPKGLA----FTDVDVDSIKIAWESPQGQ-VSRYRVTYSSPEDGIHELFPA 1679
               T  T ++ P+  +      DV   S+ ++W  P+    SR    Y   ++   + +  
Sbjct: 23822 PVTPKTPLNPPEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRVTGYYIERKETSTDKWVR 23881

Query: 1680  PDGEEDTAEL---QGLRPGSEYTVSVVALHD------DMESQPLIGTQSTAIPA-PTDLK 1729
              +  + T  +    GL P +EY   ++A +D         S+P++       P+ P +L+
Sbjct: 23882 HNKTQITTTMYTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCKDPFDKPSQPGELE 23941

Query: 1730  FTQVTPTSLSAQWTPPNV----QLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVA 1785
                ++  S++ QW  P      ++ GY V       +   K            + GL+ A
Sbjct: 23942 ILSISKDSVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERIKDKQFTIGGLLEA 24001

Query: 1786  TKYEVSVYALKDTLTSRP---AQGVVTTL-ENVSPPRRARVTDAT 1826
             T+YE  V+A  +T  SRP   A  + T L    +P  R  + D T
Sbjct: 24002 TEYEFRVFAENETGLSRPRRTAMSIKTKLTSGEAPGIRKEMKDVT 24046



 Score =  148 bits (373), Expect = 7e-35
 Identities = 289/1429 (20%), Positives = 524/1429 (36%), Gaps = 170/1429 (11%)

Query: 696   DFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYE 755
             D+T T+ ++  + +          P    S  + ++ +   ++SW    +        Y 
Sbjct: 12868 DYTITAENSSGSKSATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYI 12927

Query: 756   LSE-EGDEPQYLDLPSTA--TSVNIPDLLPGRKY-----IVNVYQISEDGEQSLILSTSQ 807
             + + E   P +  + +T   TS ++  L+ G +Y       N Y + +       ++ + 
Sbjct: 12928 VDKRETSRPNWAQVSATVPITSCSVEKLIEGHEYQFRICAENKYGVGDPVFTEPAIAKNP 12987

Query: 808   TTAPDAPPDPTVDQVDDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNL-PETA 862
                P     P +  +    + V W  P     +PITGY +    +   + T++N  P   
Sbjct: 12988 YDPPGRCDPPVISNITKDHMTVSWKPPADDGGSPITGYLLEKRETQAVNWTKVNRKPIIE 13047

Query: 863   NSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVK 922
              ++  + LQ G +Y   + A+ +     P    +             P   +  + T   
Sbjct: 13048 RTLKATGLQEGTEYEFRVTAINKAGPGKPSDASKAAYARDPQYPPGPPAFPKVYDTTRSS 13107

Query: 923   VTIMWTPPE----SAVTGYRVDVIPVNLPGEHGQRLPIS-RNTFAEVTGLSPGVTYYFKV 977
             V++ W  P     S + GY V+V   +        LP + + T  EVTGL     Y F+V
Sbjct: 13108 VSLSWGKPAYDGGSPIIGYLVEVKRADSDNWVRCNLPQNLQKTRFEVTGLMEDTQYQFRV 13167

Query: 978   FAVSHGRESKP-----------LTAQQTTKLDAPTNLQFVNETDST----VLVRWTPPRA 1022
             +AV+    S P           +      +LDA      +     T    V V+  PP  
Sbjct: 13168 YAVNKIGYSDPSDVPDKHYPKDILIPPEGELDADLRKTLILRAGVTMRLYVPVKGRPP-P 13226

Query: 1023  QITGYRLTVGLTRR-GQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGV 1081
             +IT  +  V L  R G   +     +  +    N   A +Y ++L    G +E      V
Sbjct: 13227 KITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKYILTLENSCGKKEYTIVVKV 13286

Query: 1082  FTTLQPGSSIPPYNTEVTETTIVITWTP------APRIGFKLGVRPSQGGEAPREVTSDS 1135
               T  PG  +     E+++ +  +TW P      +P I + +  R ++        T  S
Sbjct: 13287 LDT--PGPPVNVTVKEISKDSAYVTWEPPIIDGGSPIINYVVQKRDAERKSWSTVTTECS 13344

Query: 1136  G-SIVVSGLTPGVEYVYTIQVLRD------GQERDAPIVNKVVTPLSPPTNLHLEANPDT 1188
               S  V+ L  G  Y + +    +      G+ RDA  V    TP  P  +L + +   +
Sbjct: 13345 KTSFRVANLEEGKSYFFRVFAENEYGIGDPGETRDA--VKASQTP-GPVVDLKVRSVSKS 13401

Query: 1189  GVLTVSWERSTTPD---ITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNV 1245
                ++ W++  +     I GY +        + N  + V+ +     +  +L+ G EY  
Sbjct: 13402 SC-SIGWKKPHSDGGSRIIGYVVDFLT----EENKWQRVMKSLSLQYSAKDLTEGKEYTF 13456

Query: 1246  SVYTVKDDKESVPISDTIIP---AVPPPTDLRFTNIGPDT-------------MRVTWAP 1289
              V    ++ E  P   T++     V P  DL+     PD              + +   P
Sbjct: 13457 RVSAENENGEGTPSEITVVARDDVVAPDLDLKGL---PDLCYLAKENSNFRLKIPIKGKP 13513

Query: 1290  PPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLL-------PGTEYVVSVSSVY 1342
              PS+         S  K E+ +A  +    +++ V T L+          +Y +++ +V 
Sbjct: 13514 APSV---------SWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVA 13564

Query: 1343  EQHEST-PLRGRQKTGLDSPTG-IDFSDITANSFTVHWIAPR----ATITGYRIRHHPEH 1396
                E T  ++   K G+  PTG I F ++TA + T+ W  P+    + IT Y I    + 
Sbjct: 13565 GTKEGTISIKVVGKPGI--PTGPIKFDEVTAEAMTLKWAPPKDDGGSEITNY-ILEKRDS 13621

Query: 1397  FSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN------GREESPLLIGQQSTVSDV 1450
              + +         + +  +T L  G EY   + A N      G +  P++      V D 
Sbjct: 13622 VNNKWVTCASAVQKTTFRVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVPDA 13681

Query: 1451  PRDLEVVAATPTSLLISWDAPAVT----VRYYRITYGETGGNSPVQEFTVPGSKSTATIS 1506
             P    +V     S+ ++W  P  T    +  Y + + E       +    P       ++
Sbjct: 13682 PPPPNIVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTPIRMRDFKVT 13741

Query: 1507  GLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLP-- 1564
             GL  G++Y   V A+   G    S     +     ID P + +V ++  NS+++ W    
Sbjct: 13742 GLTEGLEYEFRVMAINLAGVGKPSLPSEPVVALDPIDPPGKPEVINITRNSVTLIWTEPK 13801

Query: 1565  --SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQ 1622
                   +TGY V           K       +   T+  L    +Y   + A+N +G   
Sbjct: 13802 YDGGHKLTGYIVEKRDLPSKSWMKANHVNVPECAFTVTDLVEGGKYEFRIRAKNTAGAIS 13861

Query: 1623  PLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQV----------------SRYRVTY 1666
                ++  T I + +  A T V   +IK       G                  S  +   
Sbjct: 13862 APSESTETIICKDEYEAPTIVLDPTIKDGLTIKAGDTIVLNAISILGKPLPKSSWSKAGK 13921

Query: 1667  SSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPT 1726
                   I ++   P     T +    +   EYT++             +       P P 
Sbjct: 13922 DIRPSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFGTKVEHVKVTVLDVPGP-PG 13980

Query: 1727  DLKFTQVTPTSLSAQWTPPNVQLTGYRVR--VTPKEKTGPMKEINLAPDSSSV--VVSGL 1782
              ++ + V+    +  WTPP ++  G  ++  +  K +T  +    ++ D  S   V + L
Sbjct: 13981 PVEISNVSAEKATLTWTPP-LEDGGSPIKSYILEKRETSRLLWTVVSEDIQSCRHVATKL 14039

Query: 1783  MVATKYEVSVYALKDTLTSRPAQG----VVTTLENVSPPRRARVTDATETTITISWRTKT 1838
             +   +Y   V A+       P Q     +V       PP +  V++ T+ T T+SW+   
Sbjct: 14040 IQGNEYIFRVSAVNHYGKGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSWKRPV 14099

Query: 1839  E----TITGFQVDAVPANGQTPIQRTIKPDVRSY--TITGLQPGTDYKIYLYTLN----- 1887
             +     ITG+ V+         + R IK  V      +TGLQ G+ Y+  +   N     
Sbjct: 14100 DDGGSEITGYHVERREKKSLRWV-RAIKTPVSDLRCKVTGLQEGSTYEFRVSAENRAGIG 14158

Query: 1888  --DNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPG 1941
                 A  S ++ DA+     PSN     TT  S  ++W  P       ITGY+++++K G
Sbjct: 14159 PPSEASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLAWGKPHYDGGLEITGYVVEHQKVG 14218

Query: 1942  SPPREVVPRPRPG----VTEATITGLEPGTEYTIYVIALKNNQKSEPLI 1986
                 E   +   G    +T+  +  L+   +Y   + A+ +    EP +
Sbjct: 14219 D---EAWIKDTTGTALRITQFVVPDLQTKEKYNFRISAINDAGVGEPAV 14264



 Score =  146 bits (368), Expect = 3e-34
 Identities = 299/1392 (21%), Positives = 517/1392 (37%), Gaps = 202/1392 (14%)

Query: 780   LLPGRKYIVNVYQISEDG-----EQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRP 834
             L+   +YI  V  +++ G     E   I++ +  T P  P  P         I+++W++P
Sbjct: 22707 LIKNNEYIFRVRAVNKYGPGVPVESEPIVARNSFTIPSPPGIPEEVGTGKEHIIIQWTKP 22766

Query: 835   QAP----ITGYRIVYSPSVEGSSTELNLPETANSVTL--SDLQPGVQYNITIYAVEENQE 888
             ++     I+ Y +          T +N         L  + L  G  Y   + AV     
Sbjct: 22767 ESDGGNEISNYLVDKREKKSLRWTRVNKDYVVYDTRLKVTSLMEGCDYQFRVTAVNAAGN 22826

Query: 889   STPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPV 944
             S P       +    S T   P   + V+ T   +++ WT P     + + GY +++   
Sbjct: 22827 SEPSEASNFISCREPSYTPGPPSAPRVVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEK 22886

Query: 945   NLPGEHGQRLPIS-RNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTA----QQTTKLDA 999
             +    +      + RNT   V  L  G  Y F+V AV+    S+   +    +   +++ 
Sbjct: 22887 DTDQWYRVHTNATIRNTEFTVPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEI 22946

Query: 1000  PTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQP-----------RQYNVGPSV 1048
             P +L+  ++   TV +R           RL V ++ R  P               +  + 
Sbjct: 22947 P-DLELADDLKKTVTIRAG------ASLRLMVSVSGRPPPVITWSKQGIDLASRAIIDTT 22999

Query: 1049  SKYPLR-----NLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTI 1103
               Y L      N   A +YT+      G + +     V+ T  P  S+     EV+  ++
Sbjct: 23000 ESYSLLIVDKVNRYDAGKYTIEAENQSGKKSATVLVKVYDTPGPCPSVKV--KEVSRDSV 23057

Query: 1104  VITWT------PAPRIGFKLGVRPSQGGEAPREVTSDSGSIV-VSGLTPGVEYVYTIQ-- 1154
              ITW        AP   + +  R +         T  S ++  +SGL  G  Y + +   
Sbjct: 23058 TITWEIPTIDGGAPVNNYIVEKREAAMRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPE 23117

Query: 1155  ----VLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPD---ITGYR 1207
                 +    +  DA +V++V  PL P     ++    T  +T++WE+        +TGY 
Sbjct: 23118 NIYGIGEPCETSDAVLVSEV--PLVPAKLEVVDVTKST--VTLAWEKPLYDGGSRLTGYV 23173

Query: 1208  ITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEY-----------------NVSVYTV 1250
             +       ++   +   +       T  +L+ G +Y                  V+  TV
Sbjct: 23174 LEACKAGTERWMKVV-TLKPTVLEHTVTSLNEGEQYLFRIRAQNEKGVSEPRETVTAVTV 23232

Query: 1251  KD-------DKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYS 1303
             +D       D  ++P     +PA   P +L         + +   PPP+     F     
Sbjct: 23233 QDLRVLPTIDLSTMPQKTIHVPA-GRPVEL--------VIPIAGRPPPAASW--FFAGSK 23281

Query: 1304  PVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVY-EQHESTPLRGRQKTGLDSPT 1362
               ++E    E     +   +  T +    EY + + +V     E+  +    K G   PT
Sbjct: 23282 LRESERVTVETHTKVAKLTIRETTIRDTGEYTLELKNVTGTTSETIKVIILDKPG--PPT 23339

Query: 1363  G-IDFSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSG-RPREDRVPHSRNSITLT 1416
             G I   +I A S T+ W  P     A ++GY +     H  G  P  + V  +R++   T
Sbjct: 23340 GPIKIDEIDATSITISWEPPELDGGAPLSGYVVEQRDAHRPGWLPVSESV--TRSTFKFT 23397

Query: 1417  NLTPGTEYVVSIVALN----GREESPLLIGQQSTVS--DVPRDLEVVAATPTSLLISWDA 1470
              LT G EYV  + A N    G      +I  +S++     P  L++   +   + ++W  
Sbjct: 23398 RLTEGNEYVFRVAATNRFGIGSYLQSEVIECRSSIRIPGPPETLQIFDVSRDGMTLTWYP 23457

Query: 1471  P----AVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGD 1526
             P       V  Y +   E   +  V+   VP + +    +GL  G++Y   V A+  RG 
Sbjct: 23458 PEDDGGSQVTGYIVERKEVRADRWVRVNKVPVTMTRYRSTGLTEGLEYEHRVTAINARGS 23517

Query: 1527  SPAS--SKPI-SINYRTEIDKPSQMQVTDVQDNSISVKWL----PSSSPVTGYRVTTTPK 1579
                S  SKPI +++      KP   +VTD    S+S+ W        S VTGY +     
Sbjct: 23518 GKPSRPSKPIVAMDPIAPPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKV 23577

Query: 1580  NGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLA 1639
             +    TK  T      E T+  L    EY   V A N  G  +P        +     L 
Sbjct: 23578 DQHEWTKCNTTPTKIREYTLTHLPQGAEYRFRVLACNAGGPGEPAEVPGTVKVTEM--LE 23635

Query: 1640  FTDVDVDS-IKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEY 1698
             + D ++D   +      QG V R  +        I +     +G+ D ++   +     +
Sbjct: 23636 YPDYELDERYQEGIFVRQGGVIRLTIPIKGKPFPICKW--TKEGQ-DISKRAMIATSETH 23692

Query: 1699  TVSVVALHDDMES------------QPLIGTQSTAIPAPTD----LKFTQVTPTSLSAQW 1742
             T  V+   D  +S            +  +  +   I +P      L++  +   S+   W
Sbjct: 23693 TELVIKEADRGDSGTYDLVLENKCGKKAVYIKVRVIGSPNSPEGPLEYDDIQVRSVRVSW 23752

Query: 1743  TPP----NVQLTGYRV--RVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALK 1796
              PP       + GY +  R  PK        I+     +S+VV GL    +Y   V A  
Sbjct: 23753 RPPADDGGADILGYILERREVPK---AAWYTIDSRVRGTSLVVKGLKENVEYHFRVSAEN 23809

Query: 1797  DTLTSRP--AQGVVTTLENVSPPRRA----RVTDATETTITISW-RTKTE---TITGFQV 1846
                 S+P  ++  VT    ++PP        V D T++++++SW R K +    +TG+ +
Sbjct: 23810 QFGISKPLKSEEPVTPKTPLNPPEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRVTGYYI 23869

Query: 1847  DAVPANGQTPIQRTIKPDVRS--YTITGLQPGTDYKIYLYTLND------NARSSPVVI- 1897
             +    +    ++   K  + +  YT+TGL P  +Y+  +   ND      +  S PVV  
Sbjct: 23870 ERKETSTDKWVRHN-KTQITTTMYTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCK 23928

Query: 1898  DASTAIDAPSNLRFLATTPNSLLVSWQPPRA----RITGYIIKYEKPGSPPREVVPRPRP 1953
             D       P  L  L+ + +S+ + W+ P       I GY ++Y + G    +   + R 
Sbjct: 23929 DPFDKPSQPGELEILSISKDSVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERI 23988

Query: 1954  GVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQKTPFVTHPGYDTGNGIQLPG 2013
                + TI GL   TEY   V A      S P                    T   I+   
Sbjct: 23989 KDKQFTIGGLLEATEYEFRVFAENETGLSRP------------------RRTAMSIKTKL 24030

Query: 2014  TSGQQPSVGQQM 2025
             TSG+ P + ++M
Sbjct: 24031 TSGEAPGIRKEM 24042



 Score =  134 bits (338), Expect = 8e-31
 Identities = 286/1432 (19%), Positives = 516/1432 (36%), Gaps = 199/1432 (13%)

Query: 728   VTEITASSFVVSWVSASDTVSGFRVEY--ELSEEGDEP-QYLDLPSTATSVNIPDLLPGR 784
             V+ ++A S V+SW    D        Y  E  E G    Q ++     T + +  L    
Sbjct: 22253 VSSVSAESCVLSWGEPKDGGGTEITNYIVEKRESGTTAWQLVNSSVKRTQIKVTHLTKYM 22312

Query: 785   KYIVNV-----YQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPIT 839
             +Y   V     + +S+  E + I++      P AP  P V  V   ++ +RW  P     
Sbjct: 22313 EYSFRVSSENRFGVSKPLESAPIIAEHPFVPPSAPTRPEVYHVSANAMSIRWEEPYHDGG 22372

Query: 840   GYRIVYSPSVEGSST-----ELNLPETANSVTLSDLQPGVQYNITIYAV------EENQE 888
                I Y    +  +T     E  +P    +  ++ L  G++Y    YA+      + ++ 
Sbjct: 22373 SKIIGYWVEKKERNTILWVKENKVPCLECNYKVTGLVEGLEYQFRTYALNAAGVSKASEA 22432

Query: 889   STPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPV 944
             S P++ Q         + V +P   +  +VT   V+++W+ P     S V GY ++  PV
Sbjct: 22433 SRPIMAQ---------NPVDAPGRPEVTDVTRSTVSLIWSAPAYDGGSKVVGYIIERKPV 22483

Query: 945   NLPGEHGQRLP----ISRNTFAEVTGLSPGVTYYFKVFA------VSHGRESK-PLT--- 990
             +  G+ G+ L     I  + F  VT LS G TY F+V A      +S G ES  P+T   
Sbjct: 22484 SEVGD-GRWLKCNYTIVSDNFFTVTALSEGDTYEFRVLAKNAAGVISKGSESTGPVTCRD 22542

Query: 991   --AQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPR-------- 1040
               A    +LDA  +   V     + LV      A + G      +  +G           
Sbjct: 22543 EYAPPKAELDARLHGDLVTIRAGSDLVL----DAAVGGKPEPKIIWTKGDKELDLCEKVS 22598

Query: 1041  -QYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTL--QPGSSIPPYNTE 1097
              QY    + +     +   + +YT+++     N    KA  V   +   PG       + 
Sbjct: 22599 LQYTGKRATAVIKFCDRSDSGKYTLTVK----NASGTKAVSVMVKVLDSPGPCGKLTVSR 22654

Query: 1098  VTETTIVITWTPAPRIGFKLGVRPSQGGEAP-------REVTSDSGSIVVSGLTPGVEYV 1150
             VT+    + W+            P + G A        R  TS    ++V G  P + YV
Sbjct: 22655 VTQEKCTLAWS-----------LPQEDGGAEITHYIVERRETSRLNWVIVEGECPTLSYV 22703

Query: 1151  YTIQVLRDGQE----------------RDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVS 1194
              T +++++ +                    PIV +    +  P  +  E       + + 
Sbjct: 22704 VT-RLIKNNEYIFRVRAVNKYGPGVPVESEPIVARNSFTIPSPPGIPEEVGTGKEHIIIQ 22762

Query: 1195  WERSTTP---DITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVK 1251
             W +  +    +I+ Y +        +   + +      +     +L  G +Y   V  V 
Sbjct: 22763 WTKPESDGGNEISNYLVDKREKKSLRWTRVNKDYVVYDTRLKVTSLMEGCDYQFRVTAVN 22822

Query: 1252  DDKESVP--ISDTIIPAVP-----PPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSP 1304
                 S P   S+ I    P     PP+  R  +    ++ + W  P   D    +V Y  
Sbjct: 22823 AAGNSEPSEASNFISCREPSYTPGPPSAPRVVDTTKHSISLAWTKP-MYDGGTDIVGYVL 22881

Query: 1305  VKNEEDVAE-----LSISPSDNAVVLTNLLPGTEYVVSVSSV----YEQHESTPLRGRQK 1355
                E+D  +      + +  +    + +L  G +Y   V++V      ++  +       
Sbjct: 22882 EMQEKDTDQWYRVHTNATIRNTEFTVPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPV 22941

Query: 1356  TGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVP-------- 1407
               ++ P  ++ +D    + T+   A    +     R  P     +   D           
Sbjct: 22942 ERIEIPD-LELADDLKKTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAIIDTTE 23000

Query: 1408  -HSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLI 1466
              +S   +   N     +Y +     +G++ + +L+    T    P  ++V   +  S+ I
Sbjct: 23001 SYSLLIVDKVNRYDAGKYTIEAENQSGKKSATVLVKVYDTPGPCP-SVKVKEVSRDSVTI 23059

Query: 1467  SWDAPAVT----VRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYA-- 1520
             +W+ P +     V  Y +   E    +  +  T   SK+   ISGL  G  Y   V    
Sbjct: 23060 TWEIPTIDGGAPVNNYIVEKREAAMRA-FKTVTTKCSKTLYRISGLVEGTMYYFRVLPEN 23118

Query: 1521  VTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKW----LPSSSPVTGYRVTT 1576
             + G G+   +S  + ++    +  P++++V DV  +++++ W        S +TGY +  
Sbjct: 23119 IYGIGEPCETSDAVLVSEVPLV--PAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEA 23176

Query: 1577  TPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPK 1636
                      K  T  P   E T+  L    +Y+  + AQN  G S+P        +   +
Sbjct: 23177 CKAGTERWMKVVTLKPTVLEHTVTSLNEGEQYLFRIRAQNEKGVSEPRETVTAVTVQDLR 23236

Query: 1637  GLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDG--EEDTAELQGLRP 1694
              L   D+     K     P G+     +  +         F A     E +   ++    
Sbjct: 23237 VLPTIDLSTMPQKTI-HVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTK 23295

Query: 1695  GSEYTVSVVALHDD----MESQPLIGTQSTAI---------PAPTDLKFTQVTPTSLSAQ 1741
              ++ T+    + D     +E + + GT S  I         P    +K  ++  TS++  
Sbjct: 23296 VAKLTIRETTIRDTGEYTLELKNVTGTTSETIKVIILDKPGPPTGPIKIDEIDATSITIS 23355

Query: 1742  WTPPNVQ----LTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKD 1797
             W PP +     L+GY V      + G +      P S SV  S        E + Y  + 
Sbjct: 23356 WEPPELDGGAPLSGYVVEQRDAHRPGWL------PVSESVTRSTFKFTRLTEGNEYVFRV 23409

Query: 1798  TLTSRPAQGVVTTLENVS---------PPRRARVTDATETTITISWRTKTET----ITGF 1844
               T+R   G     E +          PP   ++ D +   +T++W    +     +TG+
Sbjct: 23410 AATNRFGIGSYLQSEVIECRSSIRIPGPPETLQIFDVSRDGMTLTWYPPEDDGGSQVTGY 23469

Query: 1845  QVDAVPANGQTPIQRTIKP-DVRSYTITGLQPGTDYKIYLYTLNDNARSSP-------VV 1896
              V+         ++    P  +  Y  TGL  G +Y+  +  +N      P       V 
Sbjct: 23470 IVERKEVRADRWVRVNKVPVTMTRYRSTGLTEGLEYEHRVTAINARGSGKPSRPSKPIVA 23529

Query: 1897  IDASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREVVPRPR 1952
             +D       P N R   TT  S+ ++W  P     +++TGY+I+ +K             
Sbjct: 23530 MDPIAPPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTKCNTTP 23589

Query: 1953  PGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQKTPFVTHPGYD 2004
               + E T+T L  G EY   V+A       EP      TV+ T  + +P Y+
Sbjct: 23590 TKIREYTLTHLPQGAEYRFRVLACNAGGPGEP-AEVPGTVKVTEMLEYPDYE 23640



 Score =  132 bits (333), Expect = 3e-30
 Identities = 291/1351 (21%), Positives = 478/1351 (35%), Gaps = 186/1351 (13%)

Query: 771   TATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVR 830
             T  S++  D     KYI+ +   S  G +S  ++      P  P +  V +V   S  + 
Sbjct: 17581 TQLSIDNCDRNDAGKYILKLENSS--GSKSAFVTVKVLDTPGPPQNLAVKEVRKDSAFLV 17638

Query: 831   WSRP----QAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEEN 886
             W  P     A +  Y I    S   +   ++   +  S  + +L  G  Y   + A  E 
Sbjct: 17639 WEPPIIDGGAKVKNYVIDKRESTRKAYANVSSKCSKTSFKVENLTEGAIYYFRVMAENEF 17698

Query: 887   QESTPVVIQQETTGTPRSDTVPSPRD-LQFVEVTDVKVTIMWTPPE----SAVTGYRVDV 941
                 PV    ET    ++   PSP   +   +V+    ++MW  PE    S V GY V++
Sbjct: 17699 GVGVPV----ETVDAVKAAEPPSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVEM 17754

Query: 942   IPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKP-----------LT 990
              P     E    +  S+   A VTGLS G  Y F+V A +   +S P           LT
Sbjct: 17755 QPKGT--EKWSIVAESKVCNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLT 17812

Query: 991   AQQTTKLDAPT-NLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQP----RQYNVG 1045
              Q + KL   T ++Q   +    + V   P        R  +   + G+P     + NV 
Sbjct: 17813 IQPSLKLPFNTYSIQAGEDLKIEIPVIGRP--------RPNISWVKDGEPLKQTTRVNVE 17864

Query: 1046  PSVSKYPLR----NLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYN-TEVTE 1100
              + +   L     N     +YTV+     G   + +   V    +PG  + P    EV+ 
Sbjct: 17865 ETATSTVLHIKEGNKDDFGKYTVTATNSAGT--ATENLSVIVLEKPGPPVGPVRFDEVSA 17922

Query: 1101  TTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIV----------VSGLTPGVEYV 1150
               +VI+W P    G   G + S      R+ T+ +  +V          ++ L  G EY 
Sbjct: 17923 DFVVISWEPPAYTG---GCQISNYIVEKRDTTTTTWHMVSATVARTTIKITKLKTGTEYQ 17979

Query: 1151  YTIQVLRDGQERDAPIVNKVVTPLSP-----PTNLHLEANPDTGVLTVSWERSTTPD--- 1202
             + I    +   + AP+ +K V    P     P       +     + V W          
Sbjct: 17980 FRI-FAENRYGKSAPLDSKAVIVQYPFKEPGPPGTPFVTSISKDQMLVQWHEPVNDGGTK 18038

Query: 1203  ITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYN--VSVYTVKDDKESVPIS 1260
             I GY +     N      L +    D    T   L  GLEY   VS   +    +   +S
Sbjct: 18039 IIGYHLEQKEKNSILWVKLNKTPIQDTKFKT-TGLDEGLEYEFKVSAENIVGIGKPSKVS 18097

Query: 1261  DTIIPAVP--PPTDLRFTNIGPDTMRVTWAPPP---SIDLTNFLVRYSPVKNEEDVAELS 1315
             +  +   P  PP       I  + + + W  P       +T ++V     K+  D   + 
Sbjct: 18098 ECFVARDPCDPPGRPEAIVITRNNVTLKWKKPAYDGGSKITGYIVEK---KDLPDGRWMK 18154

Query: 1316  ISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFT 1375
              S        TN+L  TE+ VS   V +Q     +  R   G  S        ITA    
Sbjct: 18155 AS-------FTNVLE-TEFTVS-GLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARD-- 18203

Query: 1376  VHWIAPRATITG-YR---IRHHPEHF------SGRPREDRV--------------PHSRN 1411
                 AP A++   Y+   + H  E F       G+P  D V                 ++
Sbjct: 18204 -EIDAPNASLDPKYKDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKS 18262

Query: 1412  SITLTNL-------TPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSL 1464
             +I  T L       T G +Y++ +  + G +  P+ +            L+V   T    
Sbjct: 18263 TIQKTTLVVKDCIRTDGGQYILKLSNVGGTKSIPITVKVLDRPGPPEGPLKVTGVTAEKC 18322

Query: 1465  LISWDAP----AVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYA 1520
              ++W+ P       + +Y I   ET   S  Q  T   + +   ++ L PG +Y   V A
Sbjct: 18323 YLAWNPPLQDGGANISHYIIEKRETSRLSWTQVSTEVQALNYK-VTKLLPGNEYIFRVMA 18381

Query: 1521  VTGRG-DSPASSKPISI-NYRTEIDKPSQMQVTDVQDNSISVKWL----PSSSPVTGYRV 1574
             V   G   P  S P++  N       PS  +V+ +  +S+ V W        + + GY +
Sbjct: 18382 VNKYGIGEPLESGPVTACNPYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYIL 18441

Query: 1575  TTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQT------- 1627
                 K G   TK          + + GL     Y   V A+N +G  +P   +       
Sbjct: 18442 EKRDKEGVRWTKCNKKTLTDLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRACD 18501

Query: 1628  AVTNIDRPKGLAFTDVDVDSIKIAWESP----QGQVSRYRVTYSSPEDGIHELFPAPDGE 1683
             A+     P     TD    S+ +AW  P       V  Y V               P G 
Sbjct: 18502 ALYPPGPPSNPKVTDTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAADEWTTCTPPTGL 18561

Query: 1684  EDTA-ELQGLRPGSEYTVSVVALHDDMESQPL-----IGTQSTAIPAPTDLKFTQVTPTS 1737
             +     +  L+  +EY   + A++ +   +P      +  Q    P   +L         
Sbjct: 18562 QGKQFTVTKLKENTEYNFRICAINSEGVGEPATLPGSVVAQERIEPPEIELDADLRKVVV 18621

Query: 1738  LSAQWTPPNVQLTGYRVRVTPKEKTGPM----KEINLAPDSSSVVVSGLMV------ATK 1787
             L A  T         R+ VT K +  P     K   +  D + + V+           T+
Sbjct: 18622 LRASAT--------LRLFVTIKGRPEPEVKWEKAEGILTDRAQIEVTSSFTMLVIDNVTR 18673

Query: 1788  YEVSVY--ALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKT----ETI 1841
             ++   Y   L++   S+ A   V  L++ S P    + +  + ++T+SW          I
Sbjct: 18674 FDSGRYNLTLENNSGSKTAFVNVRVLDSPSAPVNLTIREVKKDSVTLSWEPPLIDGGAKI 18733

Query: 1842  TGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDAST 1901
             T + V+      +     T      ++ I  LQ G  Y   +   N+     P       
Sbjct: 18734 TNYIVEKRETTRKAYATITNNCTKTTFRIENLQEGCSYYFRVLASNEYGIGLPAETTEPV 18793

Query: 1902  AIDAP----SNLRFLATTPNSLLVSWQPPRA----RITGYIIKYEKPGSPPREVVPRPRP 1953
              +  P      +  +  T N+  + W+ P +    +ITGY+++ +  GS       + + 
Sbjct: 18794 KVSEPPLPPGRVTLVDVTRNTATIKWEKPESDGGSKITGYVVEMQTKGSEKWSTCTQVK- 18852

Query: 1954  GVTEATITGLEPGTEYTIYVIALKNNQKSEP 1984
                EATI+GL  G EY   V A+    +S+P
Sbjct: 18853 -TLEATISGLTAGEEYVFRVAAVNEKGRSDP 18882



 Score =  132 bits (332), Expect = 4e-30
 Identities = 282/1282 (21%), Positives = 484/1282 (37%), Gaps = 198/1282 (15%)

Query: 611   PVEVFITETPSQPNSHPIQWNAP---QPSHISKYILRWRPKNSVGRWKEATIPGHLNSYT 667
             PV V + E     +S  + W  P     S I  Y+++ R       W   T      S+ 
Sbjct: 13293 PVNVTVKEISK--DSAYVTWEPPIIDGGSPIINYVVQKRDAERKS-WSTVTTECSKTSFR 13349

Query: 668   IKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSES 727
             +  L+ G  Y  ++ +  +YG  +               T + V    TP  P+V     
Sbjct: 13350 VANLEEGKSYFFRVFAENEYGIGDPGE------------TRDAVKASQTP-GPVVDLK-- 13394

Query: 728   VTEITASSFVVSWVS----ASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPG 783
             V  ++ SS  + W          + G+ V++ L+EE    + +   S +   +  DL  G
Sbjct: 13395 VRSVSKSSCSIGWKKPHSDGGSRIIGYVVDF-LTEENKWQRVMK--SLSLQYSAKDLTEG 13451

Query: 784   RKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWS---RPQAPITG 840
             ++Y   V   +E+GE +    T         PD  +  + D   + + +   R + PI G
Sbjct: 13452 KEYTFRVSAENENGEGTPSEITVVARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPIKG 13511

Query: 841   YRIVYSPSVE--------GSSTELNLPETANSVTLS--DLQPGV--QYNITIYAVEENQE 888
                  +PSV          + T +++  +A + TL   D Q     +Y IT+  V   +E
Sbjct: 13512 KP---APSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKE 13568

Query: 889   STPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPV 944
              T   I  +  G P   T P    ++F EVT   +T+ W PP+    S +T Y ++    
Sbjct: 13569 GT---ISIKVVGKPGIPTGP----IKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDS 13621

Query: 945   NLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKV-----FAVSHGRESKPLTAQQTTKL-D 998
                        + + TF  VT L  G+ Y F+V     + V  G +S+P+ A+    + D
Sbjct: 13622 VNNKWVTCASAVQKTTF-RVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVPD 13680

Query: 999   APTNLQFVNETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGP-SVSKYPL 1053
             AP     V+    +V + WT P+    + ITGY L          ++ N  P  +  + +
Sbjct: 13681 APPPPNIVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTPIRMRDFKV 13740

Query: 1054  RNLQPASEYTVSLVAIK----GNQESPKATGVFTTLQPGSSIPPYNTEV---TETTIVIT 1106
               L    EY   ++AI     G    P    V   L P    PP   EV   T  ++ + 
Sbjct: 13741 TGLTEGLEYEFRVMAINLAGVGKPSLPSEPVV--ALDPID--PPGKPEVINITRNSVTLI 13796

Query: 1107  WT-PAPRIGFKLGVR-------PSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRD 1158
             WT P    G KL          PS+       V     +  V+ L  G +Y + I+    
Sbjct: 13797 WTEPKYDGGHKLTGYIVEKRDLPSKSWMKANHVNVPECAFTVTDLVEGGKYEFRIRAKNT 13856

Query: 1159  GQERDAPIVN----------KVVTPLSPPT---NLHLEANPDTGVLTV-----------S 1194
                  AP  +          +  T +  PT    L ++A  DT VL             S
Sbjct: 13857 AGAISAPSESTETIICKDEYEAPTIVLDPTIKDGLTIKAG-DTIVLNAISILGKPLPKSS 13915

Query: 1195  WERS----TTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTV 1250
             W ++       DIT  +IT+TPT+     +++     D    T    +P   +   V  V
Sbjct: 13916 WSKAGKDIRPSDIT--QITSTPTSSML--TIKYATRKDAGEYTITATNP---FGTKVEHV 13968

Query: 1251  KDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEED 1310
             K          T++    PP  +  +N+  +   +TW PP   D  + +  Y   K E  
Sbjct: 13969 KV---------TVLDVPGPPGPVEISNVSAEKATLTWTPPLE-DGGSPIKSYILEKRETS 14018

Query: 1311  VAELSISPSDNAV---VLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLD------SP 1361
                 ++   D      V T L+ G EY+  VS+V    +  P++      +D       P
Sbjct: 14019 RLLWTVVSEDIQSCRHVATKLIQGNEYIFRVSAVNHYGKGEPVQSEPVKMVDRFGPPGPP 14078

Query: 1362  TGIDFSDITANSFTVHWIAP----RATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTN 1417
                + S++T N+ TV W  P     + ITGY +    +      R  + P S     +T 
Sbjct: 14079 EKPEVSNVTKNTATVSWKRPVDDGGSEITGYHVERREKKSLRWVRAIKTPVSDLRCKVTG 14138

Query: 1418  LTPGTEYVVSIVALNGREESP-------LLIGQQSTVSDVPRDLEVVAATPTSLLISWDA 1470
             L  G+ Y   + A N     P       +L+   +     P +  V   T  S  ++W  
Sbjct: 14139 LQEGSTYEFRVSAENRAGIGPPSEASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLAWGK 14198

Query: 1471  P----AVTVRYYRITYGETGGNSPVQEFTVPGSKSTA-TISGLKPGVDYTITVYAVTGRG 1525
             P     + +  Y + + + G  + +++ T    + T   +  L+    Y   + A+   G
Sbjct: 14199 PHYDGGLEITGYVVEHQKVGDEAWIKDTTGTALRITQFVVPDLQTKEKYNFRISAINDAG 14258

Query: 1526  -DSPASSKPISINYR---TEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNG 1581
                PA    + I  R    + +  ++++ T V    +S++            VT T  N 
Sbjct: 14259 VGEPAVIPDVEIVEREMAPDFELDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNI 14318

Query: 1582  PGPTKTKTAGPDQTEMTIE---GLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRP-KG 1637
                 +      +   + I        T ++V+++  +NP+G+    V   V +   P   
Sbjct: 14319 NLKNRANIENTESFTLLIIPECNRYDTGKFVMTI--ENPAGKKSGFVNVRVLDTPGPVLN 14376

Query: 1638  LAFTDVDVDSIKIAWESP----QGQVSRY--------RVTYSSPEDGIHELFPAPDGEED 1685
             L  TD+  DS+ + W+ P      +++ Y        R +YS+     H+          
Sbjct: 14377 LRPTDITKDSVTLHWDLPLIDGGSRITNYIVEKREATRKSYSTATTKCHKC--------- 14427

Query: 1686  TAELQGLRPGSEYTVSVVALHDDMESQPLIGTQ---STAIPAPTD-LKFTQVTPTSLSAQ 1741
             T ++ GL  G EY   V+A ++    +P   T+   ++  P+P D L    +T +++S  
Sbjct: 14428 TYKVTGLSEGCEYFFRVMAENEYGIGEPTETTEPVKASEAPSPPDSLNIMDITKSTVSLA 14487

Query: 1742  WTPP----NVQLTGYRVRVTPK 1759
             W  P      ++TGY +    K
Sbjct: 14488 WPKPKHDGGSKITGYVIEAQRK 14509



 Score =  129 bits (324), Expect = 3e-29
 Identities = 296/1415 (20%), Positives = 523/1415 (36%), Gaps = 202/1415 (14%)

Query: 728   VTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTAT----SVNIPDLLPG 783
             + ++++    V W    D   G  ++  + E+ +  + +    +AT       +  L+ G
Sbjct: 11808 IVDVSSDRCTVCWDPPEDD-GGCEIQNYILEKCETKRMVWSTYSATVLTPGTTVTRLIEG 11866

Query: 784   RKYIVNVYQISEDG-----EQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ--- 835
              +YI  V   ++ G     E   +++ ++   P  P  P V +V    + V W+ P+   
Sbjct: 11867 NEYIFRVRAENKIGTGPPTESKPVIAKTKYDKPGRPDPPEVTKVSKEEMTVVWNPPEYDG 11926

Query: 836   -APITGYRIVYSPSVEGSSTELN---LPETANSVTLSDLQPGVQYNITIYAVEENQESTP 891
                ITGY +            +N   +PE    V   +L P  +Y   + A  E     P
Sbjct: 11927 GKSITGYFLEKKEKHSTRWVPVNKSAIPERRMKV--QNLLPDHEYQFRVKAENEIGIGEP 11984

Query: 892   VVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPVNL- 946
              +  +        +    P + + V+ T   +T+ W  P     + + GY V++ P    
Sbjct: 11985 SLPSRPVVAKDPIEPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAPIIGYVVEMRPKIAD 12044

Query: 947   --PGEHGQRL----PISRNTFAEVTGLSPGVTYYFKVFA---VSHGRESKPLTAQQTTKL 997
               P E  +R      + R  F  VT L     Y F+V A   V  GR ++   A +  ++
Sbjct: 12045 ASPDEGWKRCNAAAQLVRKEFT-VTSLDENQEYEFRVCAQNQVGIGRPAELKEAIKPKEI 12103

Query: 998   DAPTNLQFVNETDSTVLVRWT-----------PPRAQITGYRLTV-GLTRRGQPRQYNVG 1045
               P  +         V+VR              P  ++T  ++ +  + R+GQ    +  
Sbjct: 12104 LEPPEIDLDASMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVVRKGQVDLVDT- 12162

Query: 1046  PSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVI 1105
              +    P      + +Y+++LV   G +       V  T  P S +    ++VT+T+  +
Sbjct: 12163 MAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFVNVRVLDTPGPVSDLKV--SDVTKTSCHV 12220

Query: 1106  TWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIV----------VSGLTPGVEYVYTIQV 1155
             +W P    G   G + +      RE    + S V          V+ L PG EY + +  
Sbjct: 12221 SWAPPENDG---GSQVTHYIVEKREADRKTWSTVTPEVKKTSFHVTNLVPGNEYYFRVTA 12277

Query: 1156  LRD---GQERDAPIVNKVVTPLS---PPTNLHLEANPDTGVLTVSWE---RSTTPDITGY 1206
             + +   G   D P       PLS   PP  L +         T++W    R     I GY
Sbjct: 12278 VNEYGPGVPTDVPKPVLASDPLSEPDPPRKLEVTEMTKNSA-TLAWLPPLRDGGAKIDGY 12336

Query: 1207  RITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYT-----VKDDKESVPISD 1261
              IT+     Q  +   E       S     L  G +Y   V       V   +E+  + +
Sbjct: 12337 -ITSYREEEQPADRWTEYSVVKDLSLVVTGLKEGKKYKFRVAARNAVGVSLPREAEGVYE 12395

Query: 1262  TIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVK---NEEDV---AELS 1315
                  +PP        + P+ + +       I+   +   +   K    E++V   + L+
Sbjct: 12396 AKEQLLPPKI------LMPEQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLA 12449

Query: 1316  ISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSP----TGIDFSDITA 1371
             +  +D++ +L       +     S   E    T  +  +   +D+P       D SDI A
Sbjct: 12450 VHKADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPGPPQPPFDISDIDA 12509

Query: 1372  NSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPH----SRNSITLTNLTPGTEYVVS 1427
             ++ ++ W  P     G  I ++        R D V      ++ S  +  L PG EY+  
Sbjct: 12510 DACSLSWHIPLED-GGSNITNYIVEKCDVSRGDWVTALASVTKTSCRVGKLIPGQEYIFR 12568

Query: 1428  IVALN--GREE---SPLLIGQ-QSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRIT 1481
             + A N  G  E   SP ++ Q    V   P++  V       + ++WD P          
Sbjct: 12569 VRAENRFGISEPLTSPKMVAQFPFGVPSEPKNARVTKVNKDCIFVAWDRP---------- 12618

Query: 1482  YGETGGNSPVQEFTVPGSKSTATI----------------SGLKPGVDYTITVYAVTGRG 1525
               ++ G SP+  + +   +  + +                +GL  G++Y+  +YA+   G
Sbjct: 12619 --DSDGGSPIIGYLIERKERNSLLWVKANDTLVRSTEYPCAGLVEGLEYSFRIYALNKAG 12676

Query: 1526  DSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWL----PSSSPVTGYRVTTTPKNG 1581
              SP S     +  R  +D P + +V DV  +++S+ W        S + GY V      G
Sbjct: 12677 SSPPSKPTEYVTARMPVDPPGKPEVIDVTKSTVSLIWARPKHDGGSKIIGYFVEACKLPG 12736

Query: 1582  PGPTKTKTAGPD--QTEMTIEGLQPTVEYVVSVYAQN------PSGESQP---LVQTAVT 1630
                 +  TA     Q E T  GL+   +Y     A+       PS  S P   L +    
Sbjct: 12737 DKWVRCNTAPHQIPQEEYTATGLEEKAQYQFRAIARTAVNISPPSEPSDPVTILAENVPP 12796

Query: 1631  NIDRPKGL-------AFTDVDVDSIKIAWESPQGQVS-RYRVTYSSPEDGIHELFPAPDG 1682
              ID    +       A T+V +D+    +  P   VS +   T   P +GI     A   
Sbjct: 12797 RIDLSVAMKSLLTVKAGTNVCLDA--TVFGKPMPTVSWKKDGTLLKPAEGIK---MAMQR 12851

Query: 1683  EEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPA-PTDLKFTQVTPTSLSAQ 1741
                T EL  +        ++ A +        I  +    P  P  +K  ++        
Sbjct: 12852 NLCTLELFSVNRKDSGDYTITAENSSGSKSATIKLKVLDKPGPPASVKINKMYSDRAMLS 12911

Query: 1742  WTPP----NVQLTGYRVRVTPKEKTGP-MKEINLAPDSSSVVVSGLMVATKYEVSV---- 1792
             W PP      ++T Y   V  +E + P   +++     +S  V  L+   +Y+  +    
Sbjct: 12912 WEPPLEDGGSEITNY--IVDKRETSRPNWAQVSATVPITSCSVEKLIEGHEYQFRICAEN 12969

Query: 1793  -YALKDTLTSRPAQGVVTTLENVSPPRRAR---VTDATETTITISWRTKTE----TITGF 1844
              Y + D + + PA           PP R     +++ T+  +T+SW+   +     ITG+
Sbjct: 12970 KYGVGDPVFTEPA----IAKNPYDPPGRCDPPVISNITKDHMTVSWKPPADDGGSPITGY 13025

Query: 1845  QVDAVPANGQTPIQRTIKPDV-RSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAI 1903
              ++          +   KP + R+   TGLQ GT+Y+  +  +N      P   DAS A 
Sbjct: 13026 LLEKRETQAVNWTKVNRKPIIERTLKATGLQEGTEYEFRVTAINKAGPGKP--SDASKAA 13083

Query: 1904  DA---------PSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREVVPR 1950
              A         P+  +   TT +S+ +SW  P     + I GY+++ ++  S        
Sbjct: 13084 YARDPQYPPGPPAFPKVYDTTRSSVSLSWGKPAYDGGSPIIGYLVEVKRADSDNWVRCNL 13143

Query: 1951  PRP-GVTEATITGLEPGTEYTIYVIALKNNQKSEP 1984
             P+    T   +TGL   T+Y   V A+     S+P
Sbjct: 13144 PQNLQKTRFEVTGLMEDTQYQFRVYAVNKIGYSDP 13178



 Score =  123 bits (309), Expect = 2e-27
 Identities = 282/1358 (20%), Positives = 482/1358 (35%), Gaps = 200/1358 (14%)

Query: 780   LLPGRKYIVNVYQISEDGE----QSLILSTSQTTAPDAPPD-PTVDQVDDTSIVVRWSRP 834
             L+ G +YI  V  ++  G+    QS  +       P  PP+ P V  V   +  V W RP
Sbjct: 14039 LIQGNEYIFRVSAVNHYGKGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSWKRP 14098

Query: 835   Q----APITGYRIVYSPSVEGSSTE-LNLPETANSVTLSDLQPGVQYNITIYA-----VE 884
                  + ITGY +             +  P +     ++ LQ G  Y   + A     + 
Sbjct: 14099 VDDGGSEITGYHVERREKKSLRWVRAIKTPVSDLRCKVTGLQEGSTYEFRVSAENRAGIG 14158

Query: 885   ENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPES----AVTGYRVD 940
                E++  V+ ++    P   + P   D      T    ++ W  P       +TGY V+
Sbjct: 14159 PPSEASDSVLMKDAAYPPGPPSNPHVTD-----TTKKSASLAWGKPHYDGGLEITGYVVE 14213

Query: 941   VIPVN----LPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQ--QT 994
                V     +    G  L I++     V  L     Y F++ A++     +P      + 
Sbjct: 14214 HQKVGDEAWIKDTTGTALRITQFV---VPDLQTKEKYNFRISAINDAGVGEPAVIPDVEI 14270

Query: 995   TKLDAPTNLQFVNETDSTVLVR-------WTP----PRAQITGYRLTVGLTRRGQPRQYN 1043
              + +   + +   E   T++VR       + P    P  ++T  +  + L  R       
Sbjct: 14271 VEREMAPDFELDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKNRANIENTE 14330

Query: 1044  VGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTI 1103
                ++   P  N     ++ +++    G +       V  T  P  ++ P  T++T+ ++
Sbjct: 14331 -SFTLLIIPECNRYDTGKFVMTIENPAGKKSGFVNVRVLDTPGPVLNLRP--TDITKDSV 14387

Query: 1104  VITWT-PAPRIGFKLGVRPSQGGEAPREVTSDSGS------IVVSGLTPGVEYVYTIQVL 1156
              + W  P    G ++     +  EA R+  S + +        V+GL+ G EY + +   
Sbjct: 14388 TLHWDLPLIDGGSRITNYIVEKREATRKSYSTATTKCHKCTYKVTGLSEGCEYFFRVMAE 14447

Query: 1157  RD---GQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPD---ITGYRITT 1210
              +   G+  +     K     SPP +L++  +     ++++W +        ITGY I  
Sbjct: 14448 NEYGIGEPTETTEPVKASEAPSPPDSLNI-MDITKSTVSLAWPKPKHDGGSKITGYVIEA 14506

Query: 1211  TPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTII----PA 1266
                   Q   +  V   +   C   NL+ G EY   V  V     S P     +      
Sbjct: 14507 QRKGSDQWTHITTVKGLE---CVVRNLTEGEEYTFQVMAVNSAGRSAPRESRPVIVKEQT 14563

Query: 1267  VPPPTDLR-------FTNIGPDT---MRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSI 1316
             + P  DLR           G +    + V   P P++            K  + + + + 
Sbjct: 14564 MLPELDLRGIYQKLVIAKAGDNIKVEIPVLGRPKPTVTW----------KKGDQILKQTQ 14613

Query: 1317  SPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGL-------------DSPTG 1363
               +      + +L   E V S S  Y      PL  R   G                PTG
Sbjct: 14614 RVNFETTATSTILNINECVRSDSGPY------PLTARNIVGEVGDVITIQVHDIPGPPTG 14667

Query: 1364  -IDFSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNL 1418
              I F +++++  T  W  P       I+ Y +       S    E      R +   T L
Sbjct: 14668 PIKFDEVSSDFVTFSWDPPENDGGVPISNYVVEMRQTD-STTWVELATTVIRTTYKATRL 14726

Query: 1419  TPGTEYVVSIVALN------GREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAP- 1471
             T G EY   + A N      G   + ++      V   P   +V A T  S+ ISW  P 
Sbjct: 14727 TTGLEYQFRVKAQNRYGVGPGITSACIVANYPFKVPGPPGTPQVTAVTKDSMTISWHEPL 14786

Query: 1472  ---AVTVRYYRITYGETGGN--SPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGD 1526
                   +  Y +   E  G     V +  VPG+   +  SGL  G+ Y   V A    G 
Sbjct: 14787 SDGGSPILGYHVERKERNGILWQTVSKALVPGNIFKS--SGLTDGIAYEFRVIAENMAGK 14844

Query: 1527  SPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKW----LPSSSPVTGYRVTTTPKNGP 1582
             S  S     +     ID P +    ++  +++++KW          +T Y V        
Sbjct: 14845 SKPSKPSEPMLALDPIDPPGKPVPLNITRHTVTLKWAKPEYTGGFKITSYIVEKRDLPNG 14904

Query: 1583  GPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQ--TAVTNIDRPKGLAF 1640
                K   +   + E T+ GL     Y   V A+N +G   P  +   A+T  D       
Sbjct: 14905 RWLKANFSNILENEFTVSGLTEDAAYEFRVIAKNAAGAISPPSEPSDAITCRD------- 14957

Query: 1641  TDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGL-------- 1692
              DV+   IK+  +     + +    +    D      P  +  +D  EL+G         
Sbjct: 14958 -DVEAPKIKVDVKFKDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIA 15016

Query: 1693  -------------RPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTD--LKFTQVTPTS 1737
                          R    YT++  A +    ++ +   +    P P +  L  T+VT   
Sbjct: 15017 DFSTNLVNKDSTRRDSGAYTLT--ATNPGGFAKHIFNVKVLDRPGPPEGPLAVTEVTSEK 15074

Query: 1738  LSAQWTPP----NVQLTGYRVRVTPKEKTGPMKEINLAPD--SSSVVVSGLMVATKY--- 1788
                 W PP      ++  Y   +  K +T  +   N+A +   + + V+ L+   +Y   
Sbjct: 15075 CVLSWFPPLDDGGAKIDHY---IVQKRETSRLAWTNVASEVQVTKLKVTKLLKGNEYIFR 15131

Query: 1789  --EVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISW----RTKTETIT 1842
                V+ Y + + L S P    V       PP+   VT  T+ ++ + W          I 
Sbjct: 15132 VMAVNKYGVGEPLESEPVL-AVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEII 15190

Query: 1843  GFQVDAVPANGQTPIQRTIK--PDVRSYTITGLQPGTDYKIYLYTLNDNARSSP------ 1894
              + V+     GQ  I+   K   D+R Y ++GL  G +Y+  +   N    S+P      
Sbjct: 15191 NYIVERRDKAGQRWIKCNKKTLTDLR-YKVSGLTEGHEYEFRIMAENAAGISAPSPTSPF 15249

Query: 1895  -VVIDASTAIDAPSNLRFLATTPNSLLVSWQPP----RARITGYIIKYEKPGSPPREVVP 1949
                 D       P N R L T+ +S+ ++W  P     + ITGY+++   P     ++V 
Sbjct: 15250 YKACDTVFKPGPPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQIVT 15309

Query: 1950  RPRP-GVTEATITGLEPGTEYTIYVIALKNNQKSEPLI 1986
              P     T  TITGL    EY I + A+ +    EP +
Sbjct: 15310 PPAGLKATSYTITGLTENQEYKIRIYAMNSEGLGEPAL 15347



 Score =  121 bits (303), Expect = 9e-27
 Identities = 287/1414 (20%), Positives = 508/1414 (35%), Gaps = 177/1414 (12%)

Query: 610   GPVEVFITETPSQPNSHPIQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSY 666
             GP E  +  T        + WN P     ++IS YI+  R  + +  W + +      +Y
Sbjct: 18306 GPPEGPLKVTGVTAEKCYLAWNPPLQDGGANISHYIIEKRETSRLS-WTQVSTEVQALNY 18364

Query: 667   TIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSE 726
              +  L PG  Y  +++++ +YG  E             P+ S  VT       P   ++ 
Sbjct: 18365 KVTKLLPGNEYIFRVMAVNKYGIGE-------------PLESGPVTACNPYKPPGPPSTP 18411

Query: 727   SVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEP-----QYLDLPSTATSVNIPDLL 781
              V+ IT  S VV+W    D   G  +E  + E+ D+      +      T   + +  L 
Sbjct: 18412 EVSAITKDSMVVTWARPVDD-GGTEIEGYILEKRDKEGVRWTKCNKKTLTDLRLRVTGLT 18470

Query: 782   PGRKY-----IVNVYQISEDGEQSLILSTSQTTAPDAPP-DPTVDQVDDTSIVVRWSRP- 834
              G  Y       N   + E  E S+         P  PP +P V     +S+ + WS+P 
Sbjct: 18471 EGHSYEFRVAAENAAGVGEPSEPSVFYRACDALYPPGPPSNPKVTDTSRSSVSLAWSKPI 18530

Query: 835   ---QAPITGYRIVYSPSVEGSSTELNLPE--TANSVTLSDLQPGVQYNITIYAVEENQES 889
                 AP+ GY +    +     T    P        T++ L+   +YN  I A+      
Sbjct: 18531 YDGGAPVKGYVVEVKEAAADEWTTCTPPTGLQGKQFTVTKLKENTEYNFRICAINSEGVG 18590

Query: 890   TPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVK--------VTIMWTP-PE---SAVTGY 937
              P  +        R +      D    +V  ++        VTI   P PE       G 
Sbjct: 18591 EPATLPGSVVAQERIEPPEIELDADLRKVVVLRASATLRLFVTIKGRPEPEVKWEKAEGI 18650

Query: 938   RVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKL 997
               D   + +          +      VT    G   Y      + G ++  +  +     
Sbjct: 18651 LTDRAQIEVTSS------FTMLVIDNVTRFDSG--RYNLTLENNSGSKTAFVNVRVLDSP 18702

Query: 998   DAPTNLQFVNETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSVSKYPL 1053
              AP NL        +V + W PP     A+IT Y +    T R          + + + +
Sbjct: 18703 SAPVNLTIREVKKDSVTLSWEPPLIDGGAKITNYIVEKRETTRKAYATITNNCTKTTFRI 18762

Query: 1054  RNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYN------TEVTETTIVITW 1107
              NLQ    Y   ++A   + E        TT     S PP         +VT  T  I W
Sbjct: 18763 ENLQEGCSYYFRVLA---SNEYGIGLPAETTEPVKVSEPPLPPGRVTLVDVTRNTATIKW 18819

Query: 1108  T-PAPRIGFKLG----VRPSQGGEAPREVTS-DSGSIVVSGLTPGVEYVYTIQVLR---- 1157
               P    G K+        ++G E     T   +    +SGLT G EYV+ +  +     
Sbjct: 18820 EKPESDGGSKITGYVVEMQTKGSEKWSTCTQVKTLEATISGLTAGEEYVFRVAAVNEKGR 18879

Query: 1158  -DGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGY-RITTTPTNG 1215
              D ++   P++ + +  + P   L            V        D+    R   T    
Sbjct: 18880 SDPRQLGVPVIARDIE-IKPSVELPFHT------FNVKAREQLKIDVPFKGRPQATVNWR 18932

Query: 1216  QQGNSLEEVVHADQSSC---TFDNLSPGLEYNVSVYTVKDDKES----VPISDTIIPAVP 1268
             + G +L+E    + SS    T  ++    + +V  Y +     +    VPI+  ++    
Sbjct: 18933 KDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSNSAGSITVPITIIVLDRPG 18992

Query: 1269  PPTDLRFTNIGPDTMRVTWAPPP---SIDLTNFLVRYSPVKNEEDVAE---LSISPSDNA 1322
             PP  +R   +  D++ ++W PP       ++N++V     K E        +S + +  +
Sbjct: 18993 PPGPIRIDEVSCDSITISWNPPEYDGGCQISNYIVE----KKETTSTTWHIVSQAVARTS 19048

Query: 1323  VVLTNLLPGTEYVVSVSS-----VYEQHESTPLRGRQKTGLDSPTGI-DFSDITANSFTV 1376
             + +  L  G+EY   V +          ES+ +          P G       T ++  V
Sbjct: 19049 IKIVRLTTGSEYQFRVCAENRYGKSSYSESSAVVAEYPFSPPGPPGTPKVVHATKSTMLV 19108

Query: 1377  HWIAP----RATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN 1432
              W  P     + + GY + +         + +++  +   + ++ L  G  Y   + A N
Sbjct: 19109 TWQVPVNDGGSRVIGYHLEYKERSSILWSKANKILIADTQMKVSGLDEGLMYEYRVYAEN 19168

Query: 1433  ----GREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAP----AVTVRYYRITYGE 1484
                 G+              D P   EV   T  S+ + W  P       +  Y +   E
Sbjct: 19169 IAGIGKCSKSCEPVPARDPCDPPGQPEVTNITRKSVSLKWSKPHYDGGAKITGYIVERRE 19228

Query: 1485  TGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGD-SPASSKPISINYRTEID 1543
                   ++       ++   ++ L     Y   V+A       S  S     I  + +++
Sbjct: 19229 LPDGRWLKCNYTNIQETYFEVTELTEDQRYEFRVFARNAADSVSEPSESTGPIIVKDDVE 19288

Query: 1544  KPSQMQVTDVQDNSI--SVKWLPSSSPVTG--YRVTTTPKNG---PGPTKTKTAGPD-QT 1595
              P  M     +D  +  + + L  ++ + G    V +  K+G       +T+    D  T
Sbjct: 19289 PPRVMMDVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEIISTDNHT 19348

Query: 1596  EMTIEGL--QPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKG--LAFTDVDVDSIKIA 1651
              +T++    + T +YV+++  +N +G     V   V +   P    L    +  +   ++
Sbjct: 19349 LLTVKDCIRRDTGQYVLTL--KNVAGTRSVAVNCKVLDKPGPPAGPLEINGLTAEKCSLS 19406

Query: 1652  WESPQ----GQVSRYRVTYSSPEDGIHELFPAPDGE--EDTAELQGLRPGSEYTVSVVAL 1705
             W  PQ      +  Y V      +  H  +   +GE    + ++  L  G+EY   V  +
Sbjct: 19407 WGRPQEDGGADIDYYIV---EKRETSHLAWTICEGELQMTSCKVTKLLKGNEYIFRVTGV 19463

Query: 1706  HDDMESQPLIGTQSTAIPA---------PTDLKFTQVTPTSLSAQWTPP----NVQLTGY 1752
             +     +PL   +S AI A         PT L+ T VT  S++  W+ P      +++GY
Sbjct: 19464 NKYGVGEPL---ESVAIKALDPFTVPSPPTSLEITSVTKESMTLCWSRPESDGGSEISGY 19520

Query: 1753  RVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQ--GVVTT 1810
              +    K     ++          V  +GL    +YE  VYA      S P++   ++  
Sbjct: 19521 IIERREKNSLRWVRVNKKPVYDLRVKSTGLREGCEYEYRVYAENAAGLSLPSETSPLIRA 19580

Query: 1811  LENV---SPPRRARVTDATETTITISWRTKT----ETITGFQVD---AVPANGQTPIQRT 1860
              + V   SPP + ++ D+ +TTITI+W          ITG+ V+   +   + +T IQ  
Sbjct: 19581 EDPVFLPSPPSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEYKKSDDTDWKTSIQSL 19640

Query: 1861  IKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSP 1894
                +   YTI+GL  G +Y   + ++N    S P
Sbjct: 19641 RGTE---YTISGLTTGAEYVFRVKSVNKVGASDP 19671



 Score =  120 bits (302), Expect = 1e-26
 Identities = 326/1553 (20%), Positives = 547/1553 (35%), Gaps = 248/1553 (15%)

Query: 605  YPSSSGPVEVFITETPSQPNSHPIQWNAPQ---PSHISKYILRWRPKNSVGRWKEA-TIP 660
            Y     P+ V IT+      S  + W  P+    + I+ Y++  R K S+ RW  A T+ 
Sbjct: 6691 YDVPGPPLNVTITDVNRFGVS--LTWEPPEYDGGAEITNYVIELRDKTSI-RWDTAMTVR 6747

Query: 661  GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP 720
                S T+       V EGQ  S +        R      S +TP        E  P  P
Sbjct: 6748 AEDLSATVTD-----VVEGQEYSFRVRAQN---RIGVGKPSAATPFVKVADPIER-PSPP 6798

Query: 721  LVATSESVTEITASSFVVSWV----SASDTVSGFRVEYELSEEGDEPQY---LDLPSTAT 773
            +  TS   T+   SS  + W          + G+ +E    EEG +      + L    T
Sbjct: 6799 VNLTSSDQTQ---SSVQLKWEPPLKDGGSPILGYIIER--CEEGKDNWIRCNMKLVPELT 6853

Query: 774  SVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQV---DDTSIVVR 830
               +  L  G KY+  V   ++ G           TA DA  +PT+D     D   ++V 
Sbjct: 6854 -YKVTGLEKGNKYLYRVSAENKAGVSDPSEILGPLTADDAFVEPTMDLSAFKDGLEVIV- 6911

Query: 831  WSRP---QAPITGYRIVYSPSVEGSSTELNLPETANSVTLSD-----LQPGVQYNITIYA 882
               P     P TGY    +    G    L   +     TLS      + P  + +  IY 
Sbjct: 6912 -PNPITILVPSTGYPRPTATWCFGDKV-LETGDRVKMKTLSAYAELVISPSERSDKGIYT 6969

Query: 883  VEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYR 938
            ++       +  + +     R     +P++L+F ++T   V + W PP+    S +TGY 
Sbjct: 6970 LKLENRVKTISGEIDVNVIARPS---APKELKFGDITKDSVHLTWEPPDDDGGSPLTGYV 7026

Query: 939  VDVIPVNLPGEHGQRLPISRNTFAE-----------VTGLSPGVTYYFKVFAVSHGRESK 987
            V            ++  +SR T+ +           V  L  G  Y FKV A +     +
Sbjct: 7027 V------------EKREVSRKTWTKVMDFVTDLEFTVPDLVQGKEYLFKVCARNKCGPGE 7074

Query: 988  PLTAQQTTKL-------DAPTNLQFVNETDSTVLVRWTPPR----AQITGYRLTVGLTRR 1036
            P    +   +       D P N+++ + T +++ + W PP+    ++I GY   V    R
Sbjct: 7075 PAYVDEPVNMSTPATVPDPPENVKWRDRTANSIFLTWDPPKNDGGSRIKGY--IVERCPR 7132

Query: 1037 GQPRQYNVGPSV--SKYPLRNLQPASEYTVSLVAIK-----------------GNQESPK 1077
            G  +    G  V  +K  +  L+    Y   + A+                    QE+P+
Sbjct: 7133 GSDKWVACGEPVAETKMEVTGLEEGKWYAYRVKALNRQGASKPSRPTEEIQAVDTQEAPE 7192

Query: 1078 ATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGF-KLGVRPSQGGEAPREVTSDSG 1136
               +F  ++  + +        E    +T  P P+I + K  +   Q      E      
Sbjct: 7193 ---IFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKRITIENVPKKS 7249

Query: 1137 SIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHL-EANPDTGVLTVSW 1195
            ++ +          Y I+ +       A +   V+    PP    + +   ++ +LT + 
Sbjct: 7250 TVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNVLDKPGPPAAFDITDVTNESCLLTWNP 7309

Query: 1196 ERST-TPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSV-----YT 1249
             R      IT Y +    T+ +  + L   V       T   L P  EY   V     Y 
Sbjct: 7310 PRDDGGSKITNYVVERRATDSEVWHKLSSTVKDTNFKAT--KLIPNKEYIFRVAAENMYG 7367

Query: 1250 VKDDKESVPISDTIIPAVP-PPTDLRFTNIGPDTMRVTWAPPP---SIDLTNFLVRYSPV 1305
            V +  ++ PI+       P PPT L  ++I  D + +TW  P       +T + V     
Sbjct: 7368 VGEPVQASPITAKYQFDPPGPPTRLEPSDITKDAVTLTWCEPDDDGGSPITGYWVERLDP 7427

Query: 1306 KNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGID 1365
              ++ V    +   D    +  L    +Y   V +        P +  +   +  P    
Sbjct: 7428 DTDKWVRCNKMPVKDTTYRVKGLTNKKKYRFRVLAENLAGPGKPSKSTEPILIKDPIDPP 7487

Query: 1366 F-------SDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPR-EDRVPHSRNSI 1413
            +        D+   S  ++W  P     A I  Y I           R  + VP +++  
Sbjct: 7488 WPPGKPTVKDVGKTSVRLNWTKPEHDGGAKIESYVIEMLKTGTDEWVRVAEGVPTTQH-- 7545

Query: 1414 TLTNLTPGTEYVVSIVALNGREES-------PLLIGQQSTVSDVPRDLEVVAATPTSLLI 1466
             L  L  G EY   + A+N   ES       P+L  ++      PR LEV+  T  +  +
Sbjct: 7546 LLPGLMEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLEVINITKNTADL 7605

Query: 1467 SWDAPAVTVRYYRITYGETGGNSPVQEFTVPG---------------SKSTATISGLKPG 1511
             W  P            E  G SP+  + V                   +  T++ L  G
Sbjct: 7606 KWTVP------------EKDGGSPITNYIVEKRDVRRKGWQTVDTTVKDTKCTVTPLTEG 7653

Query: 1512 VDYTITVYAVTGRGDSPASSKPISINYR---TEIDKPSQMQVTDVQDNSISVKWLPSSS- 1567
              Y   V A    G S  +    S+  +   T    P  + V DV    + +KW P  + 
Sbjct: 7654 SLYVFRVAAENAIGQSDYTEIEDSVLAKDTFTTPGPPYALAVVDVTKRHVDLKWEPPKND 7713

Query: 1568 ---PVTGYRVTTTPKNGPGPTKT-KTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQP 1623
               P+  Y +    + G    K  KTAGPD      + ++ T E    V A+N +G   P
Sbjct: 7714 GGRPIQRYVIEKKERLGTRWVKAGKTAGPDCNFRVTDVIEGT-EVQFQVRAENEAGVGHP 7772

Query: 1624 LVQTAVTNIDRPKG-------LAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHEL 1676
               T + +I+ P         L  TD     I IAW+ P+           SP  G H +
Sbjct: 7773 SEPTEILSIEDPTSPPSPPLDLHVTDAGRKHIAIAWKPPE-------KNGGSPIIGYH-V 7824

Query: 1677 FPAPDGEEDTAEL-------------QGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIP 1723
               P G E    +             +G+ P  EY + V A++    S+P   +++    
Sbjct: 7825 EMCPVGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAIGVSEPSEISENVVAK 7884

Query: 1724 APTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLM 1783
             P D K T    T          + + G ++ +    +  P+  ++   D   V  S  +
Sbjct: 7885 DP-DCKPTIDLETH-------DIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRL 7936

Query: 1784 VATKYEVSVYALKDTLTSRPAQGVVT-TLEN----------------VSPPRRARVTDAT 1826
                  +S + L+   + R   G+ T TLEN                  P +  + +D T
Sbjct: 7937 TMKNDHISAH-LEVPKSVRADAGIYTITLENKLGSATASINVKVIGLPGPCKDIKASDIT 7995

Query: 1827 ETTITISWRTKT----ETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIY 1882
            +++  ++W          I  + ++   A  +T I      +  S+T+  L P  +Y   
Sbjct: 7996 KSSCKLTWEPPEFDGGTPILHYVLERREAGRRTYIPVMSGENKLSWTVKDLIPNGEYFFR 8055

Query: 1883 LYTLND-------NARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPP----RARIT 1931
            +  +N          ++  +  D     D P ++     T  ++ ++W+PP     ++I 
Sbjct: 8056 VKAVNKVGGGEYIELKNPVIAQDPKQPPDPPVDVEVHNPTAEAMTITWKPPLYDGGSKIM 8115

Query: 1932 GYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEP 1984
            GYII+    G    +        +   T  GLE G EY   V A      SEP
Sbjct: 8116 GYIIEKIAKGEERWKRCNEHLVPILTYTAKGLEEGKEYQFRVRAENAAGISEP 8168



 Score =  118 bits (296), Expect = 6e-26
 Identities = 316/1543 (20%), Positives = 554/1543 (35%), Gaps = 238/1543 (15%)

Query: 607   SSSGPVEVFIT----ETPSQPNSHPIQWNAPQPSHISKYILRWRP---------KNSVGR 653
             +SSG    F+T    +TP  P +  ++      +      L W P         KN V  
Sbjct: 17602 NSSGSKSAFVTVKVLDTPGPPQNLAVKEVRKDSA-----FLVWEPPIIDGGAKVKNYVID 17656

Query: 654   WKEATIPGHLN--------SYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTP 705
              +E+T   + N        S+ ++ L  G +Y  ++++  ++G                P
Sbjct: 17657 KRESTRKAYANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFG-------------VGVP 17703

Query: 706   VTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVS----ASDTVSGFRVEYELSEEGD 761
             V +        P SP      ++T+++ +S  + W          V G+ VE  +  +G 
Sbjct: 17704 VETVDAVKAAEPPSP--PGKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVE--MQPKGT 17759

Query: 762   EPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQ 821
             E   +   S   +  +  L  G++Y   V   +E G+    +      A D    P++  
Sbjct: 17760 EKWSIVAESKVCNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKL 17819

Query: 822   VDDTSIVVRWS--RPQAPITGY-RIVYSPSVEGS----STELNLPETANSVTLSDLQPGV 874
               +T  +      + + P+ G  R   S   +G     +T +N+ ETA S  L  ++ G 
Sbjct: 17820 PFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLH-IKEGN 17878

Query: 875   QYNITIYAVEENQESTPV-----VIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTP 929
             + +   Y V     +        VI  E  G P          ++F EV+   V I W P
Sbjct: 17879 KDDFGKYTVTATNSAGTATENLSVIVLEKPGPPVGP-------VRFDEVSADFVVISWEP 17931

Query: 930   PESA----VTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRE 985
             P       ++ Y V+         H     ++R T  ++T L  G  Y F++FA +   +
Sbjct: 17932 PAYTGGCQISNYIVEKRDTTTTTWHMVSATVARTTI-KITKLKTGTEYQFRIFAENRYGK 17990

Query: 986   SKPLTA-----QQTTKLDAPTNLQFVNE-TDSTVLVRWTPP----RAQITGYRLTVGLTR 1035
             S PL +     Q   K   P    FV   +   +LV+W  P      +I GY L      
Sbjct: 17991 SAPLDSKAVIVQYPFKEPGPPGTPFVTSISKDQMLVQWHEPVNDGGTKIIGYHLEQKEKN 18050

Query: 1036  RGQPRQYNVGP-SVSKYPLRNLQPASEYT--VSLVAIKGNQESPKATGVFTTLQPGSSIP 1092
                  + N  P   +K+    L    EY   VS   I G  +  K +  F    P    P
Sbjct: 18051 SILWVKLNKTPIQDTKFKTTGLDEGLEYEFKVSAENIVGIGKPSKVSECFVARDPCD--P 18108

Query: 1093  PYNTE---VTETTIVITWT-PAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVE 1148
             P   E   +T   + + W  PA   G K+     +  + P       G  + +  T  +E
Sbjct: 18109 PGRPEAIVITRNNVTLKWKKPAYDGGSKITGYIVEKKDLP------DGRWMKASFTNVLE 18162

Query: 1149  YVYTIQVLRDGQERDAPIVNK-VVTPLSPPT---------------NLHLEANPDTGVLT 1192
               +T+  L + Q  +  ++ +      S P+               N  L+      ++ 
Sbjct: 18163 TEFTVSGLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARDEIDAPNASLDPKYKDVIVV 18222

Query: 1193  VSWERSTTP-DITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLS---------PGLE 1242
              + E      DI G  I     + + G  LEE     +   T    +          G +
Sbjct: 18223 HAGETFVLEADIRGKPIPDVVWS-KDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQ 18281

Query: 1243  YNVSVYTVKDDKESVPISDTIIPAVPPPTD-LRFTNIGPDTMRVTWAPPPSIDLTNFLVR 1301
             Y + +  V   K S+PI+  ++    PP   L+ T +  +   + W PP      N    
Sbjct: 18282 YILKLSNVGGTK-SIPITVKVLDRPGPPEGPLKVTGVTAEKCYLAWNPPLQDGGANISHY 18340

Query: 1302  YSPVKNEEDVAELSISPSDNAV--VLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLD 1359
                 +    ++   +S    A+   +T LLPG EY+  V +V +     PL     T  +
Sbjct: 18341 IIEKRETSRLSWTQVSTEVQALNYKVTKLLPGNEYIFRVMAVNKYGIGEPLESGPVTACN 18400

Query: 1360  ------SPTGIDFSDITANSFTVHWIAP----RATITGYRIRHHPEHFSGRPREDRVPHS 1409
                    P+  + S IT +S  V W  P       I GY +    +      + ++   +
Sbjct: 18401 PYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDKEGVRWTKCNKKTLT 18460

Query: 1410  RNSITLTNLTPGTEYVVSIVALN----GREESPLLIGQQSTV---SDVPRDLEVVAATPT 1462
                + +T LT G  Y   + A N    G    P +  +          P + +V   + +
Sbjct: 18461 DLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRACDALYPPGPPSNPKVTDTSRS 18520

Query: 1463  SLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTA-----------------TI 1505
             S+ ++W  P               G +PV+ + V   ++ A                 T+
Sbjct: 18521 SVSLAWSKPIY------------DGGAPVKGYVVEVKEAAADEWTTCTPPTGLQGKQFTV 18568

Query: 1506  SGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPS 1565
             + LK   +Y   + A+   G    ++ P S+  +  I+ P      D++     V  L +
Sbjct: 18569 TKLKENTEYNFRICAINSEGVGEPATLPGSVVAQERIEPPEIELDADLR----KVVVLRA 18624

Query: 1566  SSPVTGYRVTTTPKNGPGP----TKTKTAGPD--QTEMTIEGLQPTVEYVV-------SV 1612
             S+ +   R+  T K  P P     K +    D  Q E+T       ++ V        ++
Sbjct: 18625 SATL---RLFVTIKGRPEPEVKWEKAEGILTDRAQIEVTSSFTMLVIDNVTRFDSGRYNL 18681

Query: 1613  YAQNPSGESQPLVQTAVTNI-DRPKGLAFTDVDVDSIKIAWESP----QGQVSRYRVTYS 1667
               +N SG     V   V +    P  L   +V  DS+ ++WE P      +++ Y V   
Sbjct: 18682 TLENNSGSKTAFVNVRVLDSPSAPVNLTIREVKKDSVTLSWEPPLIDGGAKITNYIVEKR 18741

Query: 1668  SPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPT- 1726
                   +      +  + T  ++ L+ G  Y   V+A ++     P   T+   +  P  
Sbjct: 18742 ETTRKAYATI-TNNCTKTTFRIENLQEGCSYYFRVLASNEYGIGLPAETTEPVKVSEPPL 18800

Query: 1727  ---DLKFTQVTPTSLSAQWTPP----NVQLTGYRVRVTPK--EKTGPMKEINLAPDSSSV 1777
                 +    VT  + + +W  P      ++TGY V +  K  EK     ++     +   
Sbjct: 18801 PPGRVTLVDVTRNTATIKWEKPESDGGSKITGYVVEMQTKGSEKWSTCTQVK----TLEA 18856

Query: 1778  VVSGLMVATKYEVSVYALKDTLTSRPAQ-GVVTTLENVS-------PPRRARVTDATETT 1829
              +SGL    +Y   V A+ +   S P Q GV     ++        P     V    +  
Sbjct: 18857 TISGLTAGEEYVFRVAAVNEKGRSDPRQLGVPVIARDIEIKPSVELPFHTFNVKAREQLK 18916

Query: 1830  ITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQ----PGTDYKIYLYT 1885
             I + ++ + +    ++ D     GQT  + T      S T+T L        D   Y   
Sbjct: 18917 IDVPFKGRPQATVNWRKD-----GQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELC 18971

Query: 1886  LNDNARS--SPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEK 1939
             ++++A S   P+ I        P  +R    + +S+ +SW PP      +I+ YI++ ++
Sbjct: 18972 VSNSAGSITVPITIIVLDRPGPPGPIRIDEVSCDSITISWNPPEYDGGCQISNYIVEKKE 19031

Query: 1940  PGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKS 1982
               S    +V +     T   I  L  G+EY   V A     KS
Sbjct: 19032 TTSTTWHIVSQ-AVARTSIKIVRLTTGSEYQFRVCAENRYGKS 19073



 Score =  118 bits (295), Expect = 8e-26
 Identities = 287/1359 (21%), Positives = 491/1359 (36%), Gaps = 205/1359 (15%)

Query: 780   LLPGRKYI-----VNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRP 834
             ++ G +YI     VN Y I E  E   +++ +    P  P  P V ++   S+ V WSRP
Sbjct: 20533 IIKGNEYIFRVRAVNKYGIGEPLESDSVVAKNAFVTPGPPGIPEVTKITKNSMTVVWSRP 20592

Query: 835   QA----PITGYRIVYSPSVEGSSTEL---NLPETANSVTLSDLQPGVQYNI-TIYAVEEN 886
              A     I+GY +           ++    + +T   VT        QY +  + A  + 
Sbjct: 20593 IADGGSDISGYFLEKRDKKSLGWFKVLKETIRDTRQKVTGLTENSDYQYRVCAVNAAGQG 20652

Query: 887   QESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVI 942
               S P    +        D    P  ++  + T   +T+ W+ P     SAVTGY V++ 
Sbjct: 20653 PFSEP---SEFYKAADPIDPPGPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVVEI- 20708

Query: 943   PVNLPGEHGQRLPIS-----RNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTK- 996
                  GE  +   +S     R T   V+ L PGV YYF+V AV+   + +P+   +  + 
Sbjct: 20709 ---RQGEEEEWTTVSTKGEVRTTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQA 20765

Query: 997   ---LDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQP--------RQYNVG 1045
                L+AP       E D  V +R T   A+  G  + V +  +G+P         + N+G
Sbjct: 20766 KDILEAP-------EIDLDVALR-TSVIAK-AGEDVQVLIPFKGRPPPTVTWRKDEKNLG 20816

Query: 1046  PSVSKYPLRNLQPASEYTVS----------LVAIKGNQESPKATGVFTTL--QPGSSIPP 1093
              S ++Y + N   +S  T+           ++ I+     PK++ V   +   P +    
Sbjct: 20817 -SDARYSIENTDSSSLLTIPQVTRNDTGKYILTIENGVGEPKSSTVSVKVLDTPAACQKL 20875

Query: 1094  YNTEVTETTIVITWTP------APRIGFKLGVRPS---QGGEAPREVTSDSGSIV-VSGL 1143
                 V+  T+ + W P      +P I + +  R +          + +S S  ++ +S  
Sbjct: 20876 QVKHVSRGTVTLLWDPPLIDGGSPIINYVIEKRDATKRTWSVVSHKCSSTSFKLIDLSEK 20935

Query: 1144  TPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDI 1203
             TP    V     +  G+  +     K     +P  +L ++ +  T V+ +SW   T PD 
Sbjct: 20936 TPFFFRVLAENEIGIGEPCETTEPVKAAEVPAPIRDLSMKDSTKTSVI-LSW---TKPDF 20991

Query: 1204  TGYRITTTPTNGQQGNSLEEVVHADQS-SCTFD----NLSPGLEYNVSVYTVKDDKESVP 1258
              G  + T     ++G   +   HA  S +C  +         LE+ V     K   + V 
Sbjct: 20992 DGGSVITEYVVERKGKGEQTWSHAGISKTCEIEVSQLKEQSVLEFRVFAKNEKGLSDPVT 21051

Query: 1259  ISDTIIP--AVPPPTDLRFTNIGPDTMRV----------TWAPPPSIDLTNFLVRYSPVK 1306
             I    +    + P  DL        T+R+             P PSI   ++L    P+K
Sbjct: 21052 IGPITVKELIITPEVDLSDIPGAQVTVRIGHNVHLELPYKGKPKPSI---SWLKDGLPLK 21108

Query: 1307  NEEDVAELSISPSDNAVVLT----NLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPT 1362
               E V     S ++N + L+        G +Y V + +      + P+          P 
Sbjct: 21109 ESEFV---RFSKTENKITLSIKNAKKEHGGKYTVILDNAV-CRIAVPITVITLGPPSKPK 21164

Query: 1363  G-IDFSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTN 1417
             G I F +I A+S  + W  P       IT Y I    E      +      +R +  + N
Sbjct: 21165 GPIRFDEIKADSVILSWDVPEDNGGGEITCYSIEKR-ETSQTNWKMVCSSVARTTFKVPN 21223

Query: 1418  LTPGTEYVVSIVALNGREESPLLIG------QQSTVSDVPRDLEVVAATPTSLLISWDAP 1471
             L    EY   + A N    S  L+        Q  +   P    +   T   + ++WDAP
Sbjct: 21224 LVKDAEYQFRVRAENRYGVSQPLVSSIIVAKHQFRIPGPPGKPVIYNVTSDGMSLTWDAP 21283

Query: 1472  AV----TVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDS 1527
                    V  + +   E       +  T P S      +GL  G+DY   VYA    G S
Sbjct: 21284 VYDGGSEVTGFHVEKKERNSILWQKVNTSPISGREYRATGLVEGLDYQFRVYAENSAGLS 21343

Query: 1528  PASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLP----SSSPVTGYRVTTTPKNGPG 1583
               S         + +D P      DV   +I++KW P      S + GY +     N   
Sbjct: 21344 SPSDPSKFTLAVSPVDPPGTPDYIDVTRETITLKWNPPLRDGGSKIVGYSIEKRQGNERW 21403

Query: 1584  PTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQN------PSGESQPLVQTAVTNIDRPKG 1637
               +       + + T+ GL P   Y   + A+N      P  +S  ++ T   N+  P  
Sbjct: 21404 -VRCNFTDVSECQYTVTGLSPGDRYEFRIIARNAVGTISPPSQSSGIIMTRDENV--PPI 21460

Query: 1638  LAFTDVDVDSI--------------------KIAWESPQGQVSRYRVTYSSPEDGIHELF 1677
             + F     D +                    ++ W     ++ +      +   G   LF
Sbjct: 21461 VEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEITDVLGSTSLF 21520

Query: 1678  PAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTS 1737
                   + T + +G+     YTV         +++  +  Q T       ++FT +T   
Sbjct: 21521 V----RDATRDHRGV-----YTVEAKNASGSAKAEIKVKVQDTPGKVVGPIRFTNITGEK 21571

Query: 1738  LSAQWTPP-NVQLTGYRVRVTPKEKTGPM--KEINLAPDSSSVVVSGLMVATKYEVSVYA 1794
             ++  W  P N         +  K +T  +    I    ++ S     L+   +Y+  V A
Sbjct: 21572 MTLWWDAPLNDGCAPITHYIIEKRETSRLAWALIEDKCEAQSYTAIKLINGNEYQFRVSA 21631

Query: 1795  LKDTLTSRP--AQGVVTTLENVSP--PRRARVTDATETTITISWRTKTETITGFQVDA-- 1848
             +      RP  +  VV  ++   P  P     ++ T  +IT++W  + E+  G ++    
Sbjct: 21632 VNKFGVGRPLDSDPVVAQIQYTVPDAPGIPEPSNITGNSITLTW-ARPESDGGSEIQQYI 21690

Query: 1849  -----------VPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVI 1897
                        V    + PI  T       + +TGL  G +Y+ ++  + +NA       
Sbjct: 21691 LERREKKSTRWVKVISKRPISET------RFKVTGLTEGNEYEFHV--MAENAAGVGPAS 21742

Query: 1898  DASTAIDA---------PSNLRFLATTPNSLLVSWQPP----RARITGYIIKYEKPGSPP 1944
               S  I           P+ ++   T+  ++ + W  P       I GYII+  K     
Sbjct: 21743 GISRLIKCREPVNPPGPPTVVKVTDTSKTTVSLEWSKPVFDGGMEIIGYIIEMCKADLGD 21802

Query: 1945  REVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSE 1983
                V       T  T+T L+ G EY   V A+    K +
Sbjct: 21803 WHKVNAEACVKTRYTVTDLQAGEEYKFRVSAINGAGKGD 21841



 Score =  117 bits (294), Expect = 1e-25
 Identities = 275/1247 (22%), Positives = 460/1247 (36%), Gaps = 215/1247 (17%)

Query: 908   PSP-RDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTG 966
             P P R+L+ V+V+  + T+ W PPE    G  +     N   E  +   +  +T++  T 
Sbjct: 11800 PGPVRNLKIVDVSSDRCTVCWDPPEDD-GGCEIQ----NYILEKCETKRMVWSTYS-ATV 11853

Query: 967   LSPGVT---------YYFKVFA-----VSHGRESKPLTAQQTTKLDA-----PTNLQFVN 1007
             L+PG T         Y F+V A          ESKP+ A+  TK D      P  +  V+
Sbjct: 11854 LTPGTTVTRLIEGNEYIFRVRAENKIGTGPPTESKPVIAK--TKYDKPGRPDPPEVTKVS 11911

Query: 1008  ETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSV---SKYPLRNLQPAS 1060
             + + TV+  W PP       ITGY L      +   R   V  S     +  ++NL P  
Sbjct: 11912 KEEMTVV--WNPPEYDGGKSITGYFLE--KKEKHSTRWVPVNKSAIPERRMKVQNLLPDH 11967

Query: 1061  EYTVSLVAIK----GNQESPKATGVF-TTLQPGSSIPPYNTEVTETT---IVITWTP--- 1109
             EY   + A      G    P    V    ++P    PP N  V +TT   I + W     
Sbjct: 11968 EYQFRVKAENEIGIGEPSLPSRPVVAKDPIEPPG--PPTNFRVVDTTKHSITLGWGKPVY 12025

Query: 1110  ---APRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPI 1166
                AP IG+ + +RP     +P     D G    +     V   +T+  L + QE +  +
Sbjct: 12026 DGGAPIIGYVVEMRPKIADASP-----DEGWKRCNAAAQLVRKEFTVTSLDENQEYEFRV 12080

Query: 1167  VNKVVTPLSPPTNLHLEANP-----------DTGVLTVSWERSTTPD--ITGYRITTTPT 1213
               +    +  P  L     P           D  +  +   R+  P       R    P 
Sbjct: 12081 CAQNQVGIGRPAELKEAIKPKEILEPPEIDLDASMRKLVIVRAGCPIRLFAIVRGRPAPK 12140

Query: 1214  NGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDD-------------KESVPIS 1260
                +   ++ VV   Q      +L   + + V   + +DD             +++V ++
Sbjct: 12141 VTWRKVGIDNVVRKGQV-----DLVDTMAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFVN 12195

Query: 1261  DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELS-ISP- 1318
               ++    P +DL+ +++   +  V+WAPP + D  + +  Y   K E D    S ++P 
Sbjct: 12196 VRVLDTPGPVSDLKVSDVTKTSCHVSWAPPEN-DGGSQVTHYIVEKREADRKTWSTVTPE 12254

Query: 1319  -SDNAVVLTNLLPGTEYVVSVSSVYEQHESTP-------LRGRQKTGLDSPTGIDFSDIT 1370
                 +  +TNL+PG EY   V++V E     P       L     +  D P  ++ +++T
Sbjct: 12255 VKKTSFHVTNLVPGNEYYFRVTAVNEYGPGVPTDVPKPVLASDPLSEPDPPRKLEVTEMT 12314

Query: 1371  ANSFTVHWIAP----RATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVV 1426
              NS T+ W+ P     A I GY   +  E        +       S+ +T L  G +Y  
Sbjct: 12315 KNSATLAWLPPLRDGGAKIDGYITSYREEEQPADRWTEYSVVKDLSLVVTGLKEGKKYKF 12374

Query: 1427  SIVALNGREESPLLIGQQSTVSDVPRDLEVV-----AATPTSLLISWDAPAVTVRYYRIT 1481
              + A N    S            +PR+ E V        P  +L+         +  RI 
Sbjct: 12375 RVAARNAVGVS------------LPREAEGVYEAKEQLLPPKILMPEQITIKAGKKLRIE 12422

Query: 1482  YGETGGNSPV------QEFTVPGS------KSTATISGLKPGVDYTITVYAVTGRGDSPA 1529
                 G   P       ++  V  S        +++I  +K         Y++T    S  
Sbjct: 12423 AHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGYYSLTAENSSGT 12482

Query: 1530  SSKPISINYRTEIDKPSQMQ----VTDVQDNSISVKW-LP---SSSPVTGYRVTTTPKNG 1581
              ++ I +     +D P   Q    ++D+  ++ S+ W +P     S +T Y V     + 
Sbjct: 12483 DTQKIKV---VVMDAPGPPQPPFDISDIDADACSLSWHIPLEDGGSNITNYIVEKCDVS- 12538

Query: 1582  PGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTN------IDRP 1635
              G   T  A   +T   +  L P  EY+  V A+N  G S+PL    +           P
Sbjct: 12539 RGDWVTALASVTKTSCRVGKLIPGQEYIFRVRAENRFGISEPLTSPKMVAQFPFGVPSEP 12598

Query: 1636  KGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELF--PAPDGEEDTAE--LQG 1691
             K    T V+ D I +AW+ P        + Y       + L    A D    + E    G
Sbjct: 12599 KNARVTKVNKDCIFVAWDRPDSDGGSPIIGYLIERKERNSLLWVKANDTLVRSTEYPCAG 12658

Query: 1692  LRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTD----LKFTQVTPTSLSAQWTPP-- 1745
             L  G EY+  + AL+    S P   T+      P D     +   VT +++S  W  P  
Sbjct: 12659 LVEGLEYSFRIYALNKAGSSPPSKPTEYVTARMPVDPPGKPEVIDVTKSTVSLIWARPKH 12718

Query: 1746  --NVQLTGYRVRVTPKEKTGPMKEINLAP---DSSSVVVSGLMVATKYE---VSVYALKD 1797
                 ++ GY V    K         N AP          +GL    +Y+   ++  A+  
Sbjct: 12719 DGGSKIIGYFVEAC-KLPGDKWVRCNTAPHQIPQEEYTATGLEEKAQYQFRAIARTAVNI 12777

Query: 1798  TLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKT---ETITGFQVDAV----- 1849
             +  S P+  V    ENV P  R  ++ A ++ +T+   T      T+ G  +  V     
Sbjct: 12778 SPPSEPSDPVTILAENVPP--RIDLSVAMKSLLTVKAGTNVCLDATVFGKPMPTVSWKKD 12835

Query: 1850  -----PANG-QTPIQRTI---------KPDVRSYTITGLQPGTDYKIYLYTLNDNARSSP 1894
                  PA G +  +QR +         + D   YTIT               +  ++S+ 
Sbjct: 12836 GTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTITAEN------------SSGSKSAT 12883

Query: 1895  VVIDASTAIDAPSNLRFLATTPNSLLVSWQPP----RARITGYIIKYEKPGSPPREVVPR 1950
             + +        P++++      +  ++SW+PP     + IT YI+   +   P    V  
Sbjct: 12884 IKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYIVDKRETSRPNWAQVSA 12943

Query: 1951  PRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQKTPF 1997
               P +T  ++  L  G EY   + A       +P+   +  + K P+
Sbjct: 12944 TVP-ITSCSVEKLIEGHEYQFRICAENKYGVGDPVF-TEPAIAKNPY 12988



 Score =  117 bits (293), Expect = 1e-25
 Identities = 324/1541 (21%), Positives = 541/1541 (35%), Gaps = 222/1541 (14%)

Query: 612  VEVFITETPSQPNSHPIQ----------WNAPQP---SHISKYILRWRPKNSVGRWKEAT 658
            VEV + + P  P +  I           WN P+    S I+ Y++  R  +S   W + +
Sbjct: 7279 VEVNVLDKPGPPAAFDITDVTNESCLLTWNPPRDDGGSKITNYVVERRATDSEV-WHKLS 7337

Query: 659  IPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPF 718
                  ++    L P   Y  ++ +   YG  E             PV ++ +T +    
Sbjct: 7338 STVKDTNFKATKLIPNKEYIFRVAAENMYGVGE-------------PVQASPITAKYQFD 7384

Query: 719  SPLVATSESVTEITASSFVVSWVSASDT----VSGFRVEYELSEEGDEPQYLDLPSTATS 774
             P   T    ++IT  +  ++W    D     ++G+ VE    +     +   +P   T+
Sbjct: 7385 PPGPPTRLEPSDITKDAVTLTWCEPDDDGGSPITGYWVERLDPDTDKWVRCNKMPVKDTT 7444

Query: 775  VNIPDLLPGRKYIVNVY--QISEDGEQSL----ILSTSQTTAPDAPPDPTVDQVDDTSIV 828
              +  L   +KY   V    ++  G+ S     IL       P  P  PTV  V  TS+ 
Sbjct: 7445 YRVKGLTNKKKYRFRVLAENLAGPGKPSKSTEPILIKDPIDPPWPPGKPTVKDVGKTSVR 7504

Query: 829  VRWSRPQ----APITGY--RIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYA 882
            + W++P+    A I  Y   ++ + + E       +P T +   L  L  G +Y+  + A
Sbjct: 7505 LNWTKPEHDGGAKIESYVIEMLKTGTDEWVRVAEGVPTTQH--LLPGLMEGQEYSFRVRA 7562

Query: 883  VEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYR 938
            V +  ES P           +      PR L+ + +T     + WT PE    S +T Y 
Sbjct: 7563 VNKAGESEPSEPSDPVLCREKLYPPSPPRWLEVINITKNTADLKWTVPEKDGGSPITNYI 7622

Query: 939  VDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSH-GR------ESKPLTA 991
            V+   V   G       + ++T   VT L+ G  Y F+V A +  G+      E   L  
Sbjct: 7623 VEKRDVRRKGWQTVDTTV-KDTKCTVTPLTEGSLYVFRVAAENAIGQSDYTEIEDSVLAK 7681

Query: 992  QQTTKLDAPTNLQFVNETDSTVLVRWTPPR--AQITGYRLTVGLTRRGQPRQYNVGPSVS 1049
               T    P  L  V+ T   V ++W PP+        R  +    R   R    G +  
Sbjct: 7682 DTFTTPGPPYALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKERLGTRWVKAGKTAG 7741

Query: 1050 KYPLRNLQPASEYTVSLVAIKGNQES-----PKATGVFTTLQPGS-SIPPYNTEVTET-- 1101
                  +    E T     ++   E+      + T + +   P S   PP +  VT+   
Sbjct: 7742 PDCNFRVTDVIEGTEVQFQVRAENEAGVGHPSEPTEILSIEDPTSPPSPPLDLHVTDAGR 7801

Query: 1102 -TIVITWTP------APRIGFKLGVRPSQGGEAPREVTS----DSGSIVVSGLTPGVEYV 1150
              I I W P      +P IG+ + + P  G E    V S    D    V  G+ P  EYV
Sbjct: 7802 KHIAIAWKPPEKNGGSPIIGYHVEMCP-VGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYV 7860

Query: 1151 YTIQVLRD-GQERDAPIVNKVVT--PLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYR 1207
              ++ +   G    + I   VV   P   PT + LE +    ++ +  E+ + P    +R
Sbjct: 7861 LRVRAVNAIGVSEPSEISENVVAKDPDCKPT-IDLETH---DIIVIEGEKLSIP--VPFR 7914

Query: 1208 ITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEY------NVSVYTV----KDDKESV 1257
                PT     +  +EV  +D+ +   D++S  LE       +  +YT+    K    + 
Sbjct: 7915 AVPVPTVSWHKDG-KEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATA 7973

Query: 1258 PISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSIS 1317
             I+  +I    P  D++ ++I   + ++TW PP     T  L      +       + + 
Sbjct: 7974 SINVKVIGLPGPCKDIKASDITKSSCKLTWEPPEFDGGTPILHYVLERREAGRRTYIPVM 8033

Query: 1318 PSDNAVVLT--NLLPGTEYVVSVSSV-------YEQHESTPLRGRQKTGLDSPTGIDFSD 1368
              +N +  T  +L+P  EY   V +V       Y + ++  +    K   D P  ++  +
Sbjct: 8034 SGENKLSWTVKDLIPNGEYFFRVKAVNKVGGGEYIELKNPVIAQDPKQPPDPPVDVEVHN 8093

Query: 1369 ITANSFTVHWIAP----RATITGYRIRH--HPEHFSGRPREDRVPHSRNSITLTNLTPGT 1422
             TA + T+ W  P     + I GY I      E    R  E  VP    + T   L  G 
Sbjct: 8094 PTAEAMTITWKPPLYDGGSKIMGYIIEKIAKGEERWKRCNEHLVPIL--TYTAKGLEEGK 8151

Query: 1423 EYVVSIVALNGREESPLLIGQQSTVSDVPRDL-EVVAATPTSLL----ISWDAPAVTVRY 1477
            EY   + A N    S        T +  P D  +V+  T   +     I+ DA      Y
Sbjct: 8152 EYQFRVRAENAAGISEPSRATPPTKAVDPIDAPKVILRTSLEVKRGDEIALDASISGSPY 8211

Query: 1478 YRITY------------------------GETGGNSP-----VQEFTVPGSKSTATISGL 1508
              IT+                        GE     P      Q  ++  SK   +   +
Sbjct: 8212 PTITWIKDENVIVPEEIKKRAAPLVRRRKGEVQEEEPFVLPLTQRLSIDNSKKGESQLRV 8271

Query: 1509 KPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLP---- 1564
            +  +     +Y +    D   +  P +++       P      D++  S+  KW P    
Sbjct: 8272 RDSLRPDHGLYMIKVENDHGIAKAPCTVSVLDTPGPPINFVFEDIRKTSVLCKWEPPLDD 8331

Query: 1565 SSSPVTGYRVTTTPKNGP-GPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQP 1623
              S +  Y +    K  P       T+     + ++  L    EY+  V A+N  G   P
Sbjct: 8332 GGSEIINYTLEKKDKTKPDSEWIVVTSTLRHCKYSVTKLIEGKEYLFRVRAENRFGPGPP 8391

Query: 1624 LVQTAVT------NIDRPKGLAFTDVDVDSIKIAWESPQ-------GQVSRYRVTYSSPE 1670
             V   +         D P      DV  +S+ + W  P+       G     R   S+  
Sbjct: 8392 CVSKPLVAKDPFGPPDAPDKPIVEDVTSNSMLVKWNEPKDNGSPILGYWLEKREVNSTHW 8451

Query: 1671 DGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHD------DMESQPLIGTQSTAIPA 1724
              +++           A + GL  G  Y   V A +          S P       + P 
Sbjct: 8452 SRVNKSLL----NALKANVDGLLEGLTYVFRVCAENAAGPGKFSPPSDPKTAHDPISPPG 8507

Query: 1725 PTDLKFTQVTPTSLSAQWTPP----NVQLTGYRVRVTPKEKTGPMKEINLAPDSSSV--- 1777
            P   + T  + T++  +W PP      ++ GY V    K+  G  +          V   
Sbjct: 8508 PPIPRVTDTSSTTIELEWEPPAFNGGGEIVGYFV---DKQLVGTNEWSRCTEKMIKVRQY 8564

Query: 1778 VVSGLMVATKYEVSVYALKDTLTSRPAQ-GVVTTLENVSPPRRARVTDATETTITISWRT 1836
             V  +     Y++ V A+       P +   VT  E   PP       A E  +++    
Sbjct: 8565 TVKEIREGADYKLRVSAVNAAGEGPPGETQPVTVAEPQEPP-------AVELDVSVKGGI 8617

Query: 1837 KTETITGFQVDAVPANGQTPIQRTIKPD--------------VRSYTITGLQPGTDYKIY 1882
            +       ++ AV      P +   K +               +S  I       D+  Y
Sbjct: 8618 QIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKDRVVIDNVGTKSELIIKDALRKDHGRY 8677

Query: 1883 LYTLNDNARSSPVVIDASTAIDAPS---NLRFLATTPNSLLVSWQPPR----ARITGYII 1935
            + T   N+  S          D P    +L+ + T     L++W  P     + ITG+II
Sbjct: 8678 VITAT-NSCGSKFAAARVEVFDVPGPVLDLKPVVTNRKMCLLNWSDPEDDGGSEITGFII 8736

Query: 1936 KYEKPGSPP-REVVPRPRPGVTEATITGLEPGTEYTIYVIA 1975
            + +       R+ +   R   ++  ITGL  G EY   VIA
Sbjct: 8737 ERKDAKMHTWRQPIETER---SKCDITGLLEGQEYKFRVIA 8774



 Score =  117 bits (293), Expect = 1e-25
 Identities = 292/1326 (22%), Positives = 488/1326 (36%), Gaps = 202/1326 (15%)

Query: 811   PDAPPDPT-VDQVDDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSV 865
             P  P  P   + V    + + W  P+    + IT Y I    +   +   ++      + 
Sbjct: 9720  PGPPVGPIKFESVSADQMTLSWFPPKDDGGSKITNYVIEKREANRKTWVHVSSEPKECTY 9779

Query: 866   TLSDLQPGVQYNITIYAVEENQESTPVVIQQETT-------GTPRSDTVPSPRDLQFVEV 918
             T+  L  G +Y   I A  +     P+  + ET        G P   TV S        V
Sbjct: 9780  TIPKLLEGHEYVFRIMAQNKYGIGEPLDSEPETARNLFSVPGAPDKPTVSS--------V 9831

Query: 919   TDVKVTIMWTPPE----SAVTGYRVDVIPVNLPG-EHGQRLPISRNTFA---EVTGLSPG 970
             T   +T+ W  PE    S VTGY +++        +   R PI   T     +VTGL  G
Sbjct: 9832  TRNSMTVNWEEPEYDGGSPVTGYWLEMKDTTSKRWKRVNRDPIKAMTLGVSYKVTGLIEG 9891

Query: 971   VTYYFKVFAVSHGR------ESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPR--- 1021
               Y F+V+A++          S P TA+       P   +  + T S+  + W+PP    
Sbjct: 9892  SDYQFRVYAINAAGVGPASLPSDPATARDPIAPPGPPFPKVTDWTKSSADLEWSPPLKDG 9951

Query: 1022  -AQITGYRLTVGLTRRGQPRQYNVGPSV----SKYPLRNLQPASEYT--VSLVAIKGNQE 1074
              +++TGY   V     G+  ++  G       +K  +  L+  + Y   V  V I G  E
Sbjct: 9952  GSKVTGY--IVEYKEEGK-EEWEKGKDKEVRGTKLVVTGLKEGAFYKFRVRAVNIAGIGE 10008

Query: 1075  SPKATGVFTT--------LQPGSSIPP----YNTEVTETTIVITWTPAPRIGFKLGVRPS 1122
               + T V           LQ  +S+      +   V      ++  P P + + +  R +
Sbjct: 10009 PGEVTDVIEMKDRLVSPDLQLDASVRDRIVVHAGGVIRIIAYVSGKPPPTVTWNMNER-T 10067

Query: 1123  QGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVT---PLSPPTN 1179
                EA  E T+ S S+V+       + VY++    +  ER   I+  V+    P+  P  
Sbjct: 10068 LPQEATIETTAISSSMVIKNCQRSHQGVYSLLAKNEAGERKKTIIVDVLDVPGPVGTPFL 10127

Query: 1180  LHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSP 1239
              H   N    +   S E      IT Y I    ++ +    +   V   + + T   L  
Sbjct: 10128 AHNLTNESCKLTWFSPEDDGGSPITNYVIEKRESDRRAWTPVTYTV--TRQNATVQGLIQ 10185

Query: 1240  GLEY--------NVSVYTVKDDKESVPISDTIIPAVPP-PTDLRFTNIGPDTMRVTWAPP 1290
             G  Y        ++ +    +  E++ I + I   VP  P DL    +  +T+ +TW PP
Sbjct: 10186 GKAYFFRIAAENSIGMGPFVETSEALVIREPI--TVPERPEDLEVKEVTKNTVTLTWNPP 10243

Query: 1291  P---SIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHES 1347
                   ++ N+++    +  E+     + +       +  L  G  Y   VS+V    + 
Sbjct: 10244 KYDGGSEIINYVLESRLIGTEKFHKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQG 10303

Query: 1348  TPLRGRQ----KTGLDSPT-GIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPR 1402
              P    +    K  L  PT  +DF D      T+  +     +TG         +SG+P+
Sbjct: 10304 KPSFCTKPITCKDELAPPTLHLDFRD----KLTIR-VGEAFALTG--------RYSGKPK 10350

Query: 1403  ------EDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQST--------VS 1448
                   +D      +  T    TP T  +  I A         ++ + ST        V+
Sbjct: 10351 PKVSWFKDEADVLEDDRTHIKTTPATLALEKIKAKRSDSGKYCVVVENSTGSRKGFCQVN 10410

Query: 1449  DVPRDLEVVA------ATPTSLLISWDAP----AVTVRYYRITYGETGGN--SPVQEFTV 1496
              V R    V        T   ++ISW  P       +  Y I   E G +   PV   T 
Sbjct: 10411 VVDRPGPPVGPVSFDEVTKDYMVISWKPPLDDGGSKITNYIIEKKEVGKDVWMPV---TS 10467

Query: 1497  PGSKSTATISGLKPGVDYTITVYAVTGRGDS-PASSKPISINYRTEI-DKPSQMQVTDVQ 1554
               +K+T  +S L  G DY   ++A    G S P  S  +    R  + D P Q  VT+V 
Sbjct: 10468 ASAKTTCKVSKLLEGKDYIFRIHAENLYGISDPLVSDSMKAKDRFRVPDAPDQPIVTEVT 10527

Query: 1555  DNSISVKWLP---SSSPVTGY---RVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEY 1608
              +S  V W        P+T Y   +  T  K     TK        T+  +  L    +Y
Sbjct: 10528 KDSALVTWNKPHDGGKPITNYILEKRETMSKRWARVTKDPIH--PYTKFRVPDLLEGCQY 10585

Query: 1609  VVSVYAQN------PSGESQPL-VQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQ----G 1657
                V A+N      PS  S+P+  +  +     P      D   +S+ + W+ P+     
Sbjct: 10586 EFRVSAENEIGIGDPSPPSKPVFAKDPIAKPSPPVNPEAIDTTCNSVDLTWQPPRHDGGS 10645

Query: 1658  QVSRYRVTYSSPEDGI-HELFPAPDGEEDTA-ELQGLRPGSEYTVSVVALHDDMESQPLI 1715
             ++  Y V Y    D         P+   +T  ++ GLR G  Y   V+A++   ES P  
Sbjct: 10646 KILGYIVEYQKVGDEEWRRANHTPESCPETKYKVTGLRDGQTYKFRVLAVNAAGESDP-- 10703

Query: 1716  GTQSTAIPAPTDLKFTQVTP-TSLSAQWTPPNVQLTGYRVRVT------PKEKTGPMKEI 1768
                   +P P  +K     P   L A          G  +R++      P  K    KE 
Sbjct: 10704 ----AHVPEPVLVKDRLEPPELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKED 10759

Query: 1769  NLAPDSSSVVVSGLMVATKYEV--------SVYAL--KDTLTSRPAQGVVTTLENVSPPR 1818
               AP  + + V+   V +K E+         +Y+L  ++   S+     V  L+   PPR
Sbjct: 10760 RDAPTKARIDVT--PVGSKLEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDKPGPPR 10817

Query: 1819  RARVTDATETTITISWRTKTE----TITGFQVDA--VPANGQTPIQRTIKPDVRSYTITG 1872
                V++  + +  ++W+   +     IT + V+   V +   +P+  T K   +S+    
Sbjct: 10818 DLEVSEIRKDSCYLTWKEPLDDGGSVITNYVVERRDVASAQWSPLSATSKK--KSHFAKH 10875

Query: 1873  LQPGTDYKIYLYTLNDNARSSPV-------VIDASTAIDAPSNLRFLATTPNSLLVSWQP 1925
             L  G  Y   +   N   R   V        +D       P +L  +      + + W  
Sbjct: 10876 LNEGNQYLFRVAAENQYGRGPFVETPKPIKALDPLHPPGPPKDLHHVDVDKTEVSLVWNK 10935

Query: 1926  P----RARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQK 1981
             P     + ITGY+++Y++ G+  ++ +        E  +TGL+ G  Y   V       K
Sbjct: 10936 PDRDGGSPITGYLVEYQEEGT--QDWIKFKTVTNLECVVTGLQQGKTYRFRV-------K 10986

Query: 1982  SEPLIG 1987
             +E ++G
Sbjct: 10987 AENIVG 10992



 Score =  114 bits (286), Expect = 9e-25
 Identities = 268/1373 (19%), Positives = 504/1373 (36%), Gaps = 176/1373 (12%)

Query: 766  LDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDT 825
            +D  +  TS  I +   G K    +   ++ G+    ++      P    +  V +  D 
Sbjct: 6548 IDTTAEQTSFRILEAKKGDKGRYKIVLQNKHGKAEGFINLKVIDVPGPVRNLEVTETFDG 6607

Query: 826  SIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETAN-SVTLSDLQPG-VQYNIT 879
             + + W  P     + I GY +V    ++  +  L      +   T++ LQ G V+Y   
Sbjct: 6608 EVSLAWEEPLTDGGSKIIGY-VVERRDIKRKTWVLATDRAESCEFTVTGLQKGGVEYLFR 6666

Query: 880  IYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVT 935
            + A        PV          + D    P ++   +V    V++ W PPE    + +T
Sbjct: 6667 VSARNRVGTGEPVETDNPVEARSKYDVPGPPLNVTITDVNRFGVSLTWEPPEYDGGAEIT 6726

Query: 936  GYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTT 995
             Y +++               + +  A VT +  G  Y F+V A +     KP  A    
Sbjct: 6727 NYVIELRDKTSIRWDTAMTVRAEDLSATVTDVVEGQEYSFRVRAQNRIGVGKPSAATPFV 6786

Query: 996  KL-------DAPTNLQFVNETDSTVLVRWTPP----RAQITGYRLTVGLTRRGQPR---- 1040
            K+         P NL   ++T S+V ++W PP     + I GY   +     G+      
Sbjct: 6787 KVADPIERPSPPVNLTSSDQTQSSVQLKWEPPLKDGGSPILGY--IIERCEEGKDNWIRC 6844

Query: 1041 QYNVGPSVSKYPLRNLQPASE--YTVSLVAIKGNQESPKATGVFTT----LQPGSSIPPY 1094
               + P ++ Y +  L+  ++  Y VS     G  +  +  G  T     ++P   +  +
Sbjct: 6845 NMKLVPELT-YKVTGLEKGNKYLYRVSAENKAGVSDPSEILGPLTADDAFVEPTMDLSAF 6903

Query: 1095 NTEV-----TETTIVI--TWTPAPRIGFKLGVRPSQGGEAPREVT-SDSGSIVVSGLTPG 1146
               +        TI++  T  P P   +  G +  + G+  +  T S    +V+S     
Sbjct: 6904 KDGLEVIVPNPITILVPSTGYPRPTATWCFGDKVLETGDRVKMKTLSAYAELVISPSERS 6963

Query: 1147 VEYVYTIQVLRDGQERDAPI-VNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPD--- 1202
             + +YT+++    +     I VN +  P +P      +   D+  LT  WE    PD   
Sbjct: 6964 DKGIYTLKLENRVKTISGEIDVNVIARPSAPKELKFGDITKDSVHLT--WE---PPDDDG 7018

Query: 1203 ---ITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEY--NVSVYTVKDDKESV 1257
               +TGY +     + +    + + V       T  +L  G EY   V         E  
Sbjct: 7019 GSPLTGYVVEKREVSRKTWTKVMDFV--TDLEFTVPDLVQGKEYLFKVCARNKCGPGEPA 7076

Query: 1258 PISDTIIPAVP-----PPTDLRFTNIGPDTMRVTWAPPPS---IDLTNFLVRYSPVKNEE 1309
             + + +  + P     PP ++++ +   +++ +TW PP +     +  ++V   P  +++
Sbjct: 7077 YVDEPVNMSTPATVPDPPENVKWRDRTANSIFLTWDPPKNDGGSRIKGYIVERCPRGSDK 7136

Query: 1310 DVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDI 1369
             VA      ++  + +T L  G  Y   V ++  Q  S P R  ++        +D  + 
Sbjct: 7137 WVA-CGEPVAETKMEVTGLEEGKWYAYRVKALNRQGASKPSRPTEEI-----QAVDTQEA 7190

Query: 1370 TANSFTVHWIAPRATITGYRIRHHPEHFSGRP-------REDRVPHSRNSITLTNLTPGT 1422
                  V  +A      G +I   P   +G+P       + D +      IT+ N+    
Sbjct: 7191 PEIFLDVKLLAGLTVKAGTKI-ELPATVTGKPEPKITWTKADMILKQDKRITIENVP--K 7247

Query: 1423 EYVVSIVALNGREESPLLI------GQQSTVSDV--------PRDLEVVAATPTSLLISW 1468
            +  V+IV     +    +I      G+ + V +V        P   ++   T  S L++W
Sbjct: 7248 KSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNVLDKPGPPAAFDITDVTNESCLLTW 7307

Query: 1469 DAP----AVTVRYYRITYGETGG------NSPVQEFTVPGSKSTATISGLKPGVDYTITV 1518
            + P       +  Y +    T        +S V++     +K       L P  +Y   V
Sbjct: 7308 NPPRDDGGSKITNYVVERRATDSEVWHKLSSTVKDTNFKATK-------LIPNKEYIFRV 7360

Query: 1519 YAVTGRG-DSPASSKPISINYRTE-IDKPSQMQVTDVQDNSISVKWL----PSSSPVTGY 1572
             A    G   P  + PI+  Y+ +    P++++ +D+  +++++ W        SP+TGY
Sbjct: 7361 AAENMYGVGEPVQASPITAKYQFDPPGPPTRLEPSDITKDAVTLTWCEPDDDGGSPITGY 7420

Query: 1573 RVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQP-------LV 1625
             V     +     +        T   ++GL    +Y   V A+N +G  +P       L+
Sbjct: 7421 WVERLDPDTDKWVRCNKMPVKDTTYRVKGLTNKKKYRFRVLAENLAGPGKPSKSTEPILI 7480

Query: 1626 QTAVTNIDRPKGLAFTDVDVDSIKIAWESPQ--GQVSRYRVTYSSPEDGIHELFPAPDGE 1683
            +  +     P      DV   S+++ W  P+  G            + G  E     +G 
Sbjct: 7481 KDPIDPPWPPGKPTVKDVGKTSVRLNWTKPEHDGGAKIESYVIEMLKTGTDEWVRVAEGV 7540

Query: 1684 EDTAE-LQGLRPGSEYTVSVVALHDDMESQ------PLIGTQSTAIPAPTD-LKFTQVTP 1735
              T   L GL  G EY+  V A++   ES+      P++  +    P+P   L+   +T 
Sbjct: 7541 PTTQHLLPGLMEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLEVINITK 7600

Query: 1736 TSLSAQWTPPNVQ----LTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVS 1791
             +   +WT P       +T Y V      + G  + ++     +   V+ L      E S
Sbjct: 7601 NTADLKWTVPEKDGGSPITNYIVEKRDVRRKG-WQTVDTTVKDTKCTVTPLT-----EGS 7654

Query: 1792 VYALKDTLTSRPAQGVVTTLEN----------VSPPRRARVTDATETTITISWRTKT--- 1838
            +Y  +    +   Q   T +E+            PP    V D T+  + + W       
Sbjct: 7655 LYVFRVAAENAIGQSDYTEIEDSVLAKDTFTTPGPPYALAVVDVTKRHVDLKWEPPKNDG 7714

Query: 1839 -ETITGFQVDAVPANGQTPIQ--RTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSP- 1894
               I  + ++     G   ++  +T  PD  ++ +T +  GT+ +  +   N+     P 
Sbjct: 7715 GRPIQRYVIEKKERLGTRWVKAGKTAGPDC-NFRVTDVIEGTEVQFQVRAENEAGVGHPS 7773

Query: 1895 ------VVIDASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPP 1944
                   + D ++    P +L         + ++W+PP     + I GY ++    G+  
Sbjct: 7774 EPTEILSIEDPTSPPSPPLDLHVTDAGRKHIAIAWKPPEKNGGSPIIGYHVEMCPVGTEK 7833

Query: 1945 -REVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQKTP 1996
               V  RP   +      G+ P  EY + V A+     SEP    +  V K P
Sbjct: 7834 WMRVNSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAIGVSEPSEISENVVAKDP 7886



 Score =  107 bits (266), Expect = 2e-22
 Identities = 292/1356 (21%), Positives = 513/1356 (37%), Gaps = 189/1356 (13%)

Query: 727   SVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQ--YLDLPSTA--TSVNIPDLLP 782
             +VTE+T+   V+SW    D   G ++++ + ++ +  +  + ++ S    T + +  LL 
Sbjct: 15066 AVTEVTSEKCVLSWFPPLDD-GGAKIDHYIVQKRETSRLAWTNVASEVQVTKLKVTKLLK 15124

Query: 783   GRKYI-----VNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAP 837
             G +YI     VN Y + E  E   +L+ +    PD P +P V  +   S+VV W  P + 
Sbjct: 15125 GNEYIFRVMAVNKYGVGEPLESEPVLAVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDS- 15183

Query: 838   ITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQ-------PGVQYNITIYAVEENQEST 890
               G   + +  VE            N  TL+DL+        G +Y   I A      S 
Sbjct: 15184 -DGGSEIINYIVERRDKAGQRWIKCNKKTLTDLRYKVSGLTEGHEYEFRIMAENAAGISA 15242

Query: 891   PVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNL 946
             P                  P + + ++ +   ++I W  P     S +TGY V++    L
Sbjct: 15243 PSPTSPFYKACDTVFKPGPPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIA---L 15299

Query: 947   PGEHGQRLPIS----RNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLD---A 999
             P E   ++       + T   +TGL+    Y  +++A++     +P     T K +    
Sbjct: 15300 PEEDEWQIVTPPAGLKATSYTITGLTENQEYKIRIYAMNSEGLGEPALVPGTPKAEDRML 15359

Query: 1000  PTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPR---QYNVGPSVSKYPLRNL 1056
             P  ++   +    V +R           RL V +  R  P      + G S+ K    ++
Sbjct: 15360 PPEIELDADLRKVVTIR------ACCTLRLFVPIKGRPAPEVKWARDHGESLDK---ASI 15410

Query: 1057  QPASEYTVSLVAIKGNQESPK----------ATGVFTTLQ----PGSSIPPYNTEVTETT 1102
             +  S YT+ +V      +S K          +   F  ++    PG        EVT+T+
Sbjct: 15411 ESTSSYTLLIVGNVNRFDSGKYILTVENSSGSKSAFVNVRVLDTPGPPQDLKVKEVTKTS 15470

Query: 1103  IVITWTPAPRI--GFKLGVRPSQGGEAPREVTS------DSGSIVVSGLTPGVEYVYTIQ 1154
             + +TW P P +  G K+     +  E+ R+  S         S  V  L  G  Y +  +
Sbjct: 15471 VTLTWDP-PLLDGGSKIKNYIVEKRESTRKAYSTVATNCHKTSWKVDQLQEGCSYYF--R 15527

Query: 1155  VLRDGQ------ERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPD---ITG 1205
             VL + +         A  V     PL P     ++   ++  +++SWE+        I G
Sbjct: 15528 VLAENEYGIGLPAETAESVKASERPLPPGKITLMDVTRNS--VSLSWEKPEHDGGSRILG 15585

Query: 1206  YRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYT-----VKDDKE-SVPI 1259
             Y I    T G    +    V   +++ T   L  G EY+  V       + D ++ SVP+
Sbjct: 15586 Y-IVEMQTKGSDKWATCATVKVTEATIT--GLIQGEEYSFRVSAQNEKGISDPRQLSVPV 15642

Query: 1260  --SDTIIPAVPPPTDLRFTNIGPDTMRV----TWAPPPSIDLTNFLVRYSPVKNEEDVAE 1313
                D +IP         FT +  + ++V       P P++      V   P+K       
Sbjct: 15643 IAKDLVIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNV---PLK---QTTR 15696

Query: 1314  LSISPSDNAVVLTNLLPGTE----YVVSV-SSVYEQHESTPLRGRQKTGLDSPTG-IDFS 1367
             ++   ++N  +LT      E    YVV + +S  E  E+  +    K G   PTG +   
Sbjct: 15697 VNAESTENNSLLTIKDACREDVGHYVVKLTNSAGEAIETLNVIVLDKPG--PPTGPVKMD 15754

Query: 1368  DITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTE 1423
             ++TA+S T+ W  P+    ++I  Y +    +  +   +      +R +I    L  G E
Sbjct: 15755 EVTADSITLSWGPPKYDGGSSINNYIVEKR-DTSTTTWQIVSATVARTTIKACRLKTGCE 15813

Query: 1424  YVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPT-------SLLISWDAP----A 1472
             Y   I A N   +S  L   + TV+  P  +     TP        S+ + W+ P     
Sbjct: 15814 YQFRIAAENRYGKSTYL-NSEPTVAQYPFKVPGPPGTPVVTLSSRDSMEVQWNEPISDGG 15872

Query: 1473  VTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSK 1532
               V  Y +   E      V+    P  ++    +GL+ GV+Y   V A    G    S  
Sbjct: 15873 SRVIGYHLERKERNSILWVKLNKTPIPQTKFKTTGLEEGVEYEFRVSAENIVGIGKPSKV 15932

Query: 1533  PISINYRTEIDKPSQMQVTDVQDNSISVKW----LPSSSPVTGYRVTTTPKNGPGPTKTK 1588
                   R   D P + +   V  NS++++W        S +TGY V           K  
Sbjct: 15933 SECYVARDPCDPPGRPEAIIVTRNSVTLQWKKPTYDGGSKITGYIVEKKELPEGRWMKAS 15992

Query: 1589  TAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE-SQPLVQT-AVTNIDR--PKGLAFTDVD 1644
                   T   + GL     Y   V A+N +G  S+P   T A+T  D   P  ++     
Sbjct: 15993 FTNIIDTHFEVTGLVEDHRYEFRVIARNAAGVFSEPSESTGAITARDEVDPPRISMDPKY 16052

Query: 1645  VDSIKI-AWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVV 1703
              D+I + A ES +         Y  P   I  +     G+++ +    L   S    + +
Sbjct: 16053 KDTIVVHAGESFKVDAD----IYGKPIPTIQWI----KGDQELSNTARLEIKSTDFATSL 16104

Query: 1704  ALHDD---------MESQPLIGTQSTAI-------PAPTD--LKFTQVTPTSLSAQWTPP 1745
             ++ D          ++++ + G +S  +       P P +  +  + VT    +  W PP
Sbjct: 16105 SVKDAVRVDSGNYILKAKNVAGERSVTVNVKVLDRPGPPEGPVVISGVTAEKCTLAWKPP 16164

Query: 1746  NVQLTGYRV--RVTPKEKTGPM--KEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTS 1801
              +Q  G  +   +  + +T  +    ++    + S  V+ L+   +Y   + A+      
Sbjct: 16165 -LQDGGSDIINYIVERRETSRLVWTVVDANVQTLSCKVTKLLEGNEYTFRIMAVNKYGVG 16223

Query: 1802  RPAQGVVTTLEN--VSP--PRRARVTDATETTITISWRTKT----ETITGFQVDAVPANG 1853
              P +      +N  V P  P+   VT  T+ ++ + W          I G+ ++     G
Sbjct: 16224 EPLESEPVVAKNPFVVPDAPKAPEVTTVTKDSMIVVWERPASDGGSEILGYVLEKRDKEG 16283

Query: 1854  --QTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDA-STAID------ 1904
                T   + +  ++R   +TGL    DY+  +   N    S P    A   A D      
Sbjct: 16284 IRWTRCHKRLIGELR-LRVTGLIENHDYEFRVSAENAAGLSEPSPPSAYQKACDPIYKPG 16342

Query: 1905  APSNLRFLATTPNSLLVSWQPP----RARITGYIIK 1936
              P+N + +  T +S+ +SW  P       I GYI++
Sbjct: 16343 PPNNPKVIDITRSSVFLSWSKPIYDGGCEIQGYIVE 16378



 Score =  106 bits (265), Expect = 2e-22
 Identities = 287/1431 (20%), Positives = 492/1431 (34%), Gaps = 191/1431 (13%)

Query: 730  EITASSFVVSWVSASDT----VSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRK 785
            +IT  S  ++W    D     ++G+ VE          + +D   T     +PDL+ G++
Sbjct: 7001 DITKDSVHLTWEPPDDDGGSPLTGYVVEKREVSRKTWTKVMDFV-TDLEFTVPDLVQGKE 7059

Query: 786  YIVNVYQISE--DGEQSLILSTSQTTAPDAPPDP--TVDQVDDT--SIVVRWSRPQ---- 835
            Y+  V   ++   GE + +      + P   PDP   V   D T  SI + W  P+    
Sbjct: 7060 YLFKVCARNKCGPGEPAYVDEPVNMSTPATVPDPPENVKWRDRTANSIFLTWDPPKNDGG 7119

Query: 836  APITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQ 895
            + I GY +   P           P     + ++ L+ G  Y   + A+     S P    
Sbjct: 7120 SRIKGYIVERCPRGSDKWVACGEPVAETKMEVTGLEEGKWYAYRVKALNRQGASKPSRPT 7179

Query: 896  QETTGTPRSDTVPSPRDLQFVEVTDVKV-------TIMWTPPESAVTGYRVDVIPVNLPG 948
            +E       +      D++ +    VK          +   PE  +T  + D+I      
Sbjct: 7180 EEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADMILKQDKR 7239

Query: 949  EHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNE 1008
               + +P         +  S   TY  +   V  GR +  +      K   P      + 
Sbjct: 7240 ITIENVPKKSTVTIVDSKRSDTGTYIIEAVNVC-GRATAVVEVNVLDKPGPPAAFDITDV 7298

Query: 1009 TDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTV 1064
            T+ + L+ W PPR    ++IT Y +    T      + +     + +    L P  EY  
Sbjct: 7299 TNESCLLTWNPPRDDGGSKITNYVVERRATDSEVWHKLSSTVKDTNFKATKLIPNKEYIF 7358

Query: 1065 SLVA--IKGNQESPKATGVFTTLQPGSSIPPYNTE---VTETTIVITWTP------APRI 1113
             + A  + G  E  +A+ +    Q     PP   E   +T+  + +TW        +P  
Sbjct: 7359 RVAAENMYGVGEPVQASPITAKYQFDPPGPPTRLEPSDITKDAVTLTWCEPDDDGGSPIT 7418

Query: 1114 GF---KLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTI---QVLRDGQERDAPIV 1167
            G+   +L     +     +    D+ +  V GLT   +Y + +    +   G+   +   
Sbjct: 7419 GYWVERLDPDTDKWVRCNKMPVKDT-TYRVKGLTNKKKYRFRVLAENLAGPGKPSKSTEP 7477

Query: 1168 NKVVTPLSPPTNLHLEANPDTGVLTV--SWERSTTPDITGYRITTTPTNGQQGNSLEEVV 1225
              +  P+ PP         D G  +V  +W   T P+  G     +          +E V
Sbjct: 7478 ILIKDPIDPPWPPGKPTVKDVGKTSVRLNW---TKPEHDGGAKIESYVIEMLKTGTDEWV 7534

Query: 1226 HADQSSCTFDNLSPGL----EYNVSVYTVKDDKESVPI--SDTIIPAVP-----PPTDLR 1274
               +   T  +L PGL    EY+  V  V    ES P   SD ++         PP  L 
Sbjct: 7535 RVAEGVPTTQHLLPGLMEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLE 7594

Query: 1275 FTNIGPDTMRVTWAPPPS---IDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPG 1331
              NI  +T  + W  P       +TN++V    V+ +     +  +  D    +T L  G
Sbjct: 7595 VINITKNTADLKWTVPEKDGGSPITNYIVEKRDVRRK-GWQTVDTTVKDTKCTVTPLTEG 7653

Query: 1332 TEYVVSVS-------SVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPR-- 1382
            + YV  V+       S Y + E + L     T    P  +   D+T     + W  P+  
Sbjct: 7654 SLYVFRVAAENAIGQSDYTEIEDSVLAKDTFTTPGPPYALAVVDVTKRHVDLKWEPPKND 7713

Query: 1383 --ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN----GREE 1436
                I  Y I       +   +  +      +  +T++  GTE    + A N    G   
Sbjct: 7714 GGRPIQRYVIEKKERLGTRWVKAGKTAGPDCNFRVTDVIEGTEVQFQVRAENEAGVGHPS 7773

Query: 1437 SP---LLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQE 1493
             P   L I   ++    P DL V  A    + I+W  P            E  G SP+  
Sbjct: 7774 EPTEILSIEDPTSPPSPPLDLHVTDAGRKHIAIAWKPP------------EKNGGSPIIG 7821

Query: 1494 FTVP----GSKSTATIS-------------GLKPGVDYTITVYAVTGRGDSPASSKPISI 1536
            + V     G++    ++             G+ P  +Y + V AV   G     S+P  I
Sbjct: 7822 YHVEMCPVGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAIG----VSEPSEI 7877

Query: 1537 NYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTE 1596
            +       P      D++ + I V      S    +R    P         +    D+  
Sbjct: 7878 SENVVAKDPDCKPTIDLETHDIIVIEGEKLSIPVPFRAVPVPTVSWHKDGKEVKASDRLT 7937

Query: 1597 MTIEGLQPTVEYVVSVYA---------QNPSGESQPLVQTAVTNIDRP-KGLAFTDVDVD 1646
            M  + +   +E   SV A         +N  G +   +   V  +  P K +  +D+   
Sbjct: 7938 MKNDHISAHLEVPKSVRADAGIYTITLENKLGSATASINVKVIGLPGPCKDIKASDITKS 7997

Query: 1647 SIKIAWESPQ--GQVSRYRVTYSSPEDGIHELFPAPDGEEDTA-ELQGLRPGSEYTVSVV 1703
            S K+ WE P+  G            E G     P   GE   +  ++ L P  EY   V 
Sbjct: 7998 SCKLTWEPPEFDGGTPILHYVLERREAGRRTYIPVMSGENKLSWTVKDLIPNGEYFFRVK 8057

Query: 1704 ALH-----DDME-SQPLIGTQSTAIP-APTDLKFTQVTPTSLSAQWTPP----NVQLTGY 1752
            A++     + +E   P+I       P  P D++    T  +++  W PP      ++ GY
Sbjct: 8058 AVNKVGGGEYIELKNPVIAQDPKQPPDPPVDVEVHNPTAEAMTITWKPPLYDGGSKIMGY 8117

Query: 1753 RV-RVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTL 1811
             + ++   E+       +L P   +    GL    +Y+  V A      S P++    T 
Sbjct: 8118 IIEKIAKGEERWKRCNEHLVP-ILTYTAKGLEEGKEYQFRVRAENAAGISEPSRATPPT- 8175

Query: 1812 ENVSPPRRARVTDATETTI------------------TISWRTKTETITGFQVD------ 1847
            + V P    +V   T   +                  TI+W      I   ++       
Sbjct: 8176 KAVDPIDAPKVILRTSLEVKRGDEIALDASISGSPYPTITWIKDENVIVPEEIKKRAAPL 8235

Query: 1848 --------------AVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTL-NDNA-R 1891
                           +P   +  I  + K + +      L+P  D+ +Y+  + ND+   
Sbjct: 8236 VRRRKGEVQEEEPFVLPLTQRLSIDNSKKGESQLRVRDSLRP--DHGLYMIKVENDHGIA 8293

Query: 1892 SSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPP----RARITGYIIKYEKPGSPPRE- 1946
             +P  +        P N  F      S+L  W+PP     + I  Y ++ +    P  E 
Sbjct: 8294 KAPCTVSVLDTPGPPINFVFEDIRKTSVLCKWEPPLDDGGSEIINYTLEKKDKTKPDSEW 8353

Query: 1947 VVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQKTPF 1997
            +V        + ++T L  G EY ++ +  +N     P    K  V K PF
Sbjct: 8354 IVVTSTLRHCKYSVTKLIEGKEY-LFRVRAENRFGPGPPCVSKPLVAKDPF 8403



 Score =  106 bits (264), Expect = 3e-22
 Identities = 321/1571 (20%), Positives = 563/1571 (35%), Gaps = 259/1571 (16%)

Query: 590   YGRGIGEWHCQPLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQP---SHISKYILRWR 646
             YG G+     +P++       P  V + +     N+  I+W  P+    S I+ Y++  +
Sbjct: 18781 YGIGLPAETTEPVKVSEPPLPPGRVTLVDVTR--NTATIKWEKPESDGGSKITGYVVEMQ 18838

Query: 647   PKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPV 706
              K S  +W   T    L + TI GL  G  Y  ++ ++ + G  +  +          PV
Sbjct: 18839 TKGSE-KWSTCTQVKTLEA-TISGLTAGEEYVFRVAAVNEKGRSDPRQL-------GVPV 18889

Query: 707   TSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYL 766
              +  +  E  P   L   + +V         V +         +R + +  +E      +
Sbjct: 18890 IARDI--EIKPSVELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVN-V 18946

Query: 767   DLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDP---TVDQVD 823
                 T TS++I +     K  V  Y++        I         D P  P    +D+V 
Sbjct: 18947 SSSKTVTSLSIKE---ASKEDVGTYELCVSNSAGSITVPITIIVLDRPGPPGPIRIDEVS 19003

Query: 824   DTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNIT 879
               SI + W+ P+      I+ Y +    +   +   ++      S+ +  L  G +Y   
Sbjct: 19004 CDSITISWNPPEYDGGCQISNYIVEKKETTSTTWHIVSQAVARTSIKIVRLTTGSEYQFR 19063

Query: 880   I-----YAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE--- 931
             +     Y      ES+ VV +      P S   P P   + V  T   + + W  P    
Sbjct: 19064 VCAENRYGKSSYSESSAVVAEY-----PFSPPGP-PGTPKVVHATKSTMLVTWQVPVNDG 19117

Query: 932   -SAVTGYRVDVIP-VNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFA---VSHGRES 986
              S V GY ++     ++      ++ I+ +T  +V+GL  G+ Y ++V+A      G+ S
Sbjct: 19118 GSRVIGYHLEYKERSSILWSKANKILIA-DTQMKVSGLDEGLMYEYRVYAENIAGIGKCS 19176

Query: 987   K---PLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPR----AQITGY-----RLTVG-- 1032
             K   P+ A+     D P   +  N T  +V ++W+ P     A+ITGY      L  G  
Sbjct: 19177 KSCEPVPARDPC--DPPGQPEVTNITRKSVSLKWSKPHYDGGAKITGYIVERRELPDGRW 19234

Query: 1033  --------------LTRRGQPRQY-------NVGPSVSKYPLRNLQPASEYTVSLVAIKG 1071
                           +T   + ++Y       N   SVS+         SE T  ++ +K 
Sbjct: 19235 LKCNYTNIQETYFEVTELTEDQRYEFRVFARNAADSVSE--------PSESTGPII-VKD 19285

Query: 1072  NQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGF-KLGVRPSQGGEAPRE 1130
             + E P+   V   ++    I     EV +    I   P P I + K G+   +       
Sbjct: 19286 DVEPPR---VMMDVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERARTEII 19342

Query: 1131  VTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGV 1190
              T +   + V          Y + +      R   +  KV+    PP    LE N  T  
Sbjct: 19343 STDNHTLLTVKDCIRRDTGQYVLTLKNVAGTRSVAVNCKVLDKPGPPAG-PLEINGLTAE 19401

Query: 1191  -LTVSWERSTTP---DITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEY--- 1243
               ++SW R       DI  Y +    T+       E  +    +SC    L  G EY   
Sbjct: 19402 KCSLSWGRPQEDGGADIDYYIVEKRETSHLAWTICEGELQ--MTSCKVTKLLKGNEYIFR 19459

Query: 1244  --NVSVYTVKDDKESVPISDTIIPAVP-PPTDLRFTNIGPDTMRVTWAPPPS---IDLTN 1297
                V+ Y V +  ESV I       VP PPT L  T++  ++M + W+ P S    +++ 
Sbjct: 19460 VTGVNKYGVGEPLESVAIKALDPFTVPSPPTSLEITSVTKESMTLCWSRPESDGGSEISG 19519

Query: 1298  FLVRYSPVKNEEDVAELSISP-SDNAVVLTNLLPGTEYVVSV-----SSVYEQHESTPL- 1350
             +++     KN      ++  P  D  V  T L  G EY   V     + +    E++PL 
Sbjct: 19520 YIIERRE-KNSLRWVRVNKKPVYDLRVKSTGLREGCEYEYRVYAENAAGLSLPSETSPLI 19578

Query: 1351  RGRQKTGLDS-PTGIDFSDITANSFTVHWIAP----RATITGYRIRHHPEHFSGRPREDR 1405
             R      L S P+     D    + T+ W+ P     A ITGY + +  +       +  
Sbjct: 19579 RAEDPVFLPSPPSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEY--KKSDDTDWKTS 19636

Query: 1406  VPHSRNS-ITLTNLTPGTEYVVSIVALN-----------------GREESPLLIGQQSTV 1447
             +   R +  T++ LT G EYV  + ++N                  REE PL        
Sbjct: 19637 IQSLRGTEYTISGLTTGAEYVFRVKSVNKVGASDPSDSSDPQIAKEREEEPLF----DID 19692

Query: 1448  SDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFT-VPGSKSTATI- 1505
             S++ + L V A    ++ + +    V      + + +   +   + +     S+++ TI 
Sbjct: 19693 SEMRKTLIVKAGASFTMTVPFRGRPVP----NVLWSKPDTDLRTRAYVDTTDSRTSLTIE 19748

Query: 1506  -SGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKW-L 1563
              +       YT+T+  V       A+S  + +        P+ + V DV   S  + W +
Sbjct: 19749 NANRNDSGKYTLTIQNVLS-----AASLTLVVKVLDTPGPPTNITVQDVTKESAVLSWDV 19803

Query: 1564  PSS---SPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE 1620
             P +   +PV  Y +     +        T   ++    +  LQ    Y   V  +N  G 
Sbjct: 19804 PENDGGAPVKNYHIEKREASKKAWVSV-TNNCNRLSYKVTNLQEGAIYYFRVSGENEFGV 19862

Query: 1621  SQPLVQTAVTNIDR----PKGLAFTDVDVDSIKIAWESPQGQVSRYRVTY--SSPEDGIH 1674
               P        I      P+ L  T +  DS+ + W  P+       V Y   + E G  
Sbjct: 19863 GIPAETKEGVKITEKPSPPEKLGVTSISKDSVSLTWLKPEHDGGSRIVHYVVEALEKGQK 19922

Query: 1675  ELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVT 1734
                     +     + GLR  SEY   V A     E+Q         +  P +L    + 
Sbjct: 19923 NWVKCAVAKSTHHVVSGLRENSEYFFRVFA-----ENQ-------AGLSDPREL----LL 19966

Query: 1735  PTSLSAQWTPPNVQL-----------TGYRVRVTPKEKTGPMKEINLAPD---------- 1773
             P  +  Q  PP + +            G  ++V       P+ ++ L+ D          
Sbjct: 19967 PVLIKEQLEPPEIDMKNFPSHTVYVRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRF 20026

Query: 1774  SSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGV------VTTLENVSPPR-RARVTDAT 1826
             ++ +    L +  K  V+  A +  +T+  + G       +  L+   PP     ++D T
Sbjct: 20027 NTEITAENLTINLKESVTADAGRYEITAANSSGTTKAFINIVVLDRPGPPTGPVVISDIT 20086

Query: 1827  ETTITISWR---------------TKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTIT 1871
             E ++T+ W                 K ET T     AV       + RT+        + 
Sbjct: 20087 EESVTLKWEPPKYDGGSQVTNYILLKRETST-----AVWTEVSATVARTM------MKVM 20135

Query: 1872  GLQPGTDYKIYL-----YTLNDNARSSPVVIDASTAIDAPSNLRFLA-TTPNSLLVSWQP 1925
              L  G +Y+  +     + ++D+  S+ V +        P +  ++   T  S+ V W  
Sbjct: 20136 KLTTGEEYQFRIKAENRFGISDHIDSACVTVKLPYTTPGPPSTPWVTNVTRESITVGWHE 20195

Query: 1926  P----RARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIAL----- 1976
             P     + + GY ++ +   S   +   +     T   +T +  G  Y   V A      
Sbjct: 20196 PVSNGGSAVVGYHLEMKDRNSILWQKANKLVIRTTHFKVTTISAGLIYEFRVYAENAAGV 20255

Query: 1977  -KNNQKSEPLI 1986
              K +  SEP++
Sbjct: 20256 GKPSHPSEPVL 20266



 Score =  105 bits (263), Expect = 4e-22
 Identities = 305/1451 (21%), Positives = 530/1451 (36%), Gaps = 208/1451 (14%)

Query: 688   GHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWV----SA 743
             G Q + R      S S PV    +     P  P+      VT +T+    ++W       
Sbjct: 17196 GGQYILRASNVAGSKSFPVNVKVLDRPGPPEGPV-----QVTGVTSEKCSLTWSPPLQDG 17250

Query: 744   SDTVSGFRVEYELSEEGDEPQYLDLPS--TATSVNIPDLLPGRKYI-----VNVYQISED 796
                +S + VE     E     +  + S     S+ +  LL G +Y+     VN Y + E 
Sbjct: 17251 GSDISHYVVE---KRETSRLAWTVVASEVVTNSLKVTKLLEGNEYVFRIMAVNKYGVGEP 17307

Query: 797   GEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ----APITGYRIVYSPSVEG- 851
              E + +L  +    P  P    V  +   S+ V W+RP     + I GY IV      G 
Sbjct: 17308 LESAPVLMKNPFVLPGPPKSLEVTNIAKDSMTVCWNRPDSDGGSEIIGY-IVEKRDRSGI 17366

Query: 852   ---SSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVP 908
                   +  + +    VT        ++ ++        E +P  +  +    P     P
Sbjct: 17367 RWIKCNKRRITDLRLRVTGLTEDHEYEFRVSAENAAGVGEPSPATVYYKAC-DPVFKPGP 17425

Query: 909   SPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPGEHGQRLPIS---RNTF 961
              P +   V+ T   +T+ W  P     S + GY V++   +   E  Q +      R T 
Sbjct: 17426 -PTNAHIVDTTKNSITLAWGKPIYDGGSEILGYVVEICKAD--EEEWQIVTPQTGLRVTR 17482

Query: 962   AEVTGLSPGVTYYFKVFAVSH----GRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRW 1017
              E++ L+    Y  +V A++        S P T +   KL+AP  L   +E    ++VR 
Sbjct: 17483 FEISKLTEHQEYKIRVCALNKVGLGEATSVPGTVKPEDKLEAP-ELDLDSELRKGIVVR- 17540

Query: 1018  TPPRAQITGYRLTVGLTRRGQPR----------------QYNVGPSVSKYPLRNL--QPA 1059
                     G    + +  +G+P                 Q   G + ++  + N     A
Sbjct: 17541 -------AGGSARIHIPFKGRPTPEITWSREEGEFTDKVQIEKGVNYTQLSIDNCDRNDA 17593

Query: 1060  SEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYN---TEVTETTIVITWTPAPRI--G 1114
              +Y + L    G++ +     V  T  PG   PP N    EV + +  + W P P I  G
Sbjct: 17594 GKYILKLENSSGSKSAFVTVKVLDT--PG---PPQNLAVKEVRKDSAFLVWEP-PIIDGG 17647

Query: 1115  FKLGVRPSQGGEAPREVTSD------SGSIVVSGLTPGVEYVYTIQVLRD---GQERDAP 1165
              K+        E+ R+  ++        S  V  LT G  Y + +    +   G   +  
Sbjct: 17648 AKVKNYVIDKRESTRKAYANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFGVGVPVETV 17707

Query: 1166  IVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPD---ITGYRITTTPTNGQQGNSLE 1222
                K   P SPP  + L     T   ++ WE+        + GY +   P   ++ + + 
Sbjct: 17708 DAVKAAEPPSPPGKVTLTDVSQTSA-SLMWEKPEHDGGSRVLGYVVEMQPKGTEKWSIVA 17766

Query: 1223  EVVHADQSSCTFDNLSPGLEY--NVSVYTVKDDKE----SVPI---SDTIIPAVPPPTDL 1273
             E   +   +     LS G EY   V  Y  K   +     VP+     TI P++  P + 
Sbjct: 17767 E---SKVCNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKLPFNT 17823

Query: 1274  RFTNIGPD---TMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLP 1330
                  G D    + V   P P+I   +++    P+K       +++  +  + VL ++  
Sbjct: 17824 YSIQAGEDLKIEIPVIGRPRPNI---SWVKDGEPLK---QTTRVNVEETATSTVL-HIKE 17876

Query: 1331  GTE------YVVSVSSVYEQHESTPLRGRQKTGLDSPTG-IDFSDITANSFTVHWIAPRA 1383
             G +       V + +S     E+  +   +K G   P G + F +++A+   + W  P  
Sbjct: 17877 GNKDDFGKYTVTATNSAGTATENLSVIVLEKPG--PPVGPVRFDEVSADFVVISWEPPAY 17934

Query: 1384  T----ITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPL 1439
             T    I+ Y +    +  +          +R +I +T L  GTEY   I A N   +S  
Sbjct: 17935 TGGCQISNYIVEKR-DTTTTTWHMVSATVARTTIKITKLKTGTEYQFRIFAENRYGKSAP 17993

Query: 1440  LIGQQSTVS------DVPRDLEVVAATPTSLLISWDAP----AVTVRYYRITYGETGGNS 1489
             L  +   V         P    V + +   +L+ W  P       +  Y +   E     
Sbjct: 17994 LDSKAVIVQYPFKEPGPPGTPFVTSISKDQMLVQWHEPVNDGGTKIIGYHLEQKEKNSIL 18053

Query: 1490  PVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQ 1549
              V+    P   +    +GL  G++Y   V A    G    S        R   D P + +
Sbjct: 18054 WVKLNKTPIQDTKFKTTGLDEGLEYEFKVSAENIVGIGKPSKVSECFVARDPCDPPGRPE 18113

Query: 1550  VTDVQDNSISVKW----LPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPT 1605
                +  N++++KW        S +TGY V           K       +TE T+ GL   
Sbjct: 18114 AIVITRNNVTLKWKKPAYDGGSKITGYIVEKKDLPDGRWMKASFTNVLETEFTVSGLVED 18173

Query: 1606  VEYVVSVYAQNPSGE-SQPLVQT-AVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYR 1663
               Y   V A+N +G  S+P   + A+T  D        ++D  +  +  +     V    
Sbjct: 18174 QRYEFRVIARNAAGNFSEPSDSSGAITARD--------EIDAPNASLDPKYKDVIVVHAG 18225

Query: 1664  VTYSSPED----GIHELFPAPDGE--EDTAELQGLRPGSEYTVSVV--ALHDD-----ME 1710
              T+    D     I ++  + DG+  E+TA    ++   + T  VV   +  D     ++
Sbjct: 18226 ETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQYILK 18285

Query: 1711  SQPLIGTQSTAI-------PAPTD--LKFTQVTPTSLSAQWTPPNVQLTGYRVR--VTPK 1759
                + GT+S  I       P P +  LK T VT       W PP +Q  G  +   +  K
Sbjct: 18286 LSNVGGTKSIPITVKVLDRPGPPEGPLKVTGVTAEKCYLAWNPP-LQDGGANISHYIIEK 18344

Query: 1760  EKTGPMK--EINLAPDSSSVVVSGLMVATKY-----EVSVYALKDTLTSRPAQGVVTTLE 1812
              +T  +   +++    + +  V+ L+   +Y      V+ Y + + L S P        +
Sbjct: 18345 RETSRLSWTQVSTEVQALNYKVTKLLPGNEYIFRVMAVNKYGIGEPLESGPVT-ACNPYK 18403

Query: 1813  NVSPPRRARVTDATETTITISWRTKTE----TITGFQVDAVPANG--QTPIQRTIKPDVR 1866
                PP    V+  T+ ++ ++W    +     I G+ ++     G   T   +    D+R
Sbjct: 18404 PPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDKEGVRWTKCNKKTLTDLR 18463

Query: 1867  SYTITGLQPGTDYKIYLYTLNDNARSSPV-------VIDASTAIDAPSNLRFLATTPNSL 1919
                +TGL  G  Y+  +   N      P          DA      PSN +   T+ +S+
Sbjct: 18464 -LRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRACDALYPPGPPSNPKVTDTSRSSV 18522

Query: 1920  LVSWQPP----RARITGYIIKYEKPGSPPREVVPRPRPGV--TEATITGLEPGTEYTIYV 1973
              ++W  P     A + GY+++  K  +        P  G+   + T+T L+  TEY   +
Sbjct: 18523 SLAWSKPIYDGGAPVKGYVVEV-KEAAADEWTTCTPPTGLQGKQFTVTKLKENTEYNFRI 18581

Query: 1974  IALKNNQKSEP 1984
              A+ +    EP
Sbjct: 18582 CAINSEGVGEP 18592



 Score =  103 bits (258), Expect = 2e-21
 Identities = 284/1417 (20%), Positives = 486/1417 (34%), Gaps = 169/1417 (11%)

Query: 606   PSSSGPVEVFITETPSQPNSHPIQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGH 662
             P   GPVE+    +        + W  P     S I  YIL  R  + +  W   +    
Sbjct: 13976 PGPPGPVEI----SNVSAEKATLTWTPPLEDGGSPIKSYILEKRETSRL-LWTVVSEDIQ 14030

Query: 663   LNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLV 722
                +    L  G  Y  ++ ++  YG  E             PV S  V        P  
Sbjct: 14031 SCRHVATKLIQGNEYIFRVSAVNHYGKGE-------------PVQSEPVKMVDRFGPPGP 14077

Query: 723   ATSESVTEITASSFVVSWVSASDT----VSGFRVEYELSEEGDEPQYLDLPSTATSVNIP 778
                  V+ +T ++  VSW    D     ++G+ VE    +     + +  P +     + 
Sbjct: 14078 PEKPEVSNVTKNTATVSWKRPVDDGGSEITGYHVERREKKSLRWVRAIKTPVSDLRCKVT 14137

Query: 779   DLLPGRKYIVNVYQISEDG------EQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWS 832
              L  G  Y   V   +  G          +L       P  P +P V      S  + W 
Sbjct: 14138 GLQEGSTYEFRVSAENRAGIGPPSEASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLAWG 14197

Query: 833   RPQ----APITGYRIVYSPSVEGSSTELNLPETANSVT---LSDLQPGVQYNITIYAVEE 885
             +P       ITGY +V    V   +   +   TA  +T   + DLQ   +YN  I A+ +
Sbjct: 14198 KPHYDGGLEITGY-VVEHQKVGDEAWIKDTTGTALRITQFVVPDLQTKEKYNFRISAIND 14256

Query: 886   NQESTPVVIQQ-ETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPV 944
                  P VI   E      +       +L+   V    ++I    P        V     
Sbjct: 14257 AGVGEPAVIPDVEIVEREMAPDFELDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKD 14316

Query: 945   NLPGEHGQRLPISRNTFAEVTGLSPGVTYYF--KVFAVSHGRESKPLTAQQTTKLDAP-- 1000
             N+  ++   +    NT +    + P    Y   K          K         LD P  
Sbjct: 14317 NINLKNRANI---ENTESFTLLIIPECNRYDTGKFVMTIENPAGKKSGFVNVRVLDTPGP 14373

Query: 1001  -TNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSK-----YPLR 1054
               NL+  + T  +V + W  P     G R+T  +  + +  + +   + +K     Y + 
Sbjct: 14374 VLNLRPTDITKDSVTLHWDLPLID-GGSRITNYIVEKREATRKSYSTATTKCHKCTYKVT 14432

Query: 1055  NLQPASEYTVSLVAIK--GNQESPKATGVFTTLQPGSSIPPYNT-EVTETTIVITWTPAP 1111
              L    EY   ++A    G  E  + T      +  S     N  ++T++T+ + W P P
Sbjct: 14433 GLSEGCEYFFRVMAENEYGIGEPTETTEPVKASEAPSPPDSLNIMDITKSTVSLAW-PKP 14491

Query: 1112  R-------IGFKLGVRPSQGGEAPREVTSDSG-SIVVSGLTPGVEYVYTIQVL----RDG 1159
             +        G+ +  +  +G +    +T+  G   VV  LT G EY + +  +    R  
Sbjct: 14492 KHDGGSKITGYVIEAQ-RKGSDQWTHITTVKGLECVVRNLTEGEEYTFQVMAVNSAGRSA 14550

Query: 1160  QERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWE--RSTTPDITGYRITTTPTNGQQ 1217
                  P++ K  T L     L L       V+  + +  +   P +   + T T   G Q
Sbjct: 14551 PRESRPVIVKEQTMLP---ELDLRGIYQKLVIAKAGDNIKVEIPVLGRPKPTVTWKKGDQ 14607

Query: 1218  G-NSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAV-----PPPT 1271
                  + V     ++ T  N++  +  +   Y +        + D I   V     PP  
Sbjct: 14608 ILKQTQRVNFETTATSTILNINECVRSDSGPYPLTARNIVGEVGDVITIQVHDIPGPPTG 14667

Query: 1272  DLRFTNIGPDTMRVTWAPPPS---IDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNL 1328
              ++F  +  D +  +W PP +   + ++N++V      +   V EL+ +        T L
Sbjct: 14668 PIKFDEVSSDFVTFSWDPPENDGGVPISNYVVEMRQTDSTTWV-ELATTVIRTTYKATRL 14726

Query: 1329  LPGTEYVVSVSS-----VYEQHESTPLRGRQKTGLDSPTGI-DFSDITANSFTVHWIAP- 1381
               G EY   V +     V     S  +       +  P G    + +T +S T+ W  P 
Sbjct: 14727 TTGLEYQFRVKAQNRYGVGPGITSACIVANYPFKVPGPPGTPQVTAVTKDSMTISWHEPL 14786

Query: 1382  ---RATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN------ 1432
                 + I GY +     +        +     N    + LT G  Y   ++A N      
Sbjct: 14787 SDGGSPILGYHVERKERNGILWQTVSKALVPGNIFKSSGLTDGIAYEFRVIAENMAGKSK 14846

Query: 1433  -GREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPV 1491
               +   P+L          P  L +   T T   + W  P  T  +   +Y     + P 
Sbjct: 14847 PSKPSEPMLALDPIDPPGKPVPLNITRHTVT---LKWAKPEYTGGFKITSYIVEKRDLPN 14903

Query: 1492  QEFTVPG----SKSTATISGLKPGVDYTITVYAVTGRGD-SPASSKPISINYRTEIDKPS 1546
               +         ++  T+SGL     Y   V A    G  SP S    +I  R +++ P 
Sbjct: 14904 GRWLKANFSNILENEFTVSGLTEDAAYEFRVIAKNAAGAISPPSEPSDAITCRDDVEAPK 14963

Query: 1547  QMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTK------TKTAGPDQTEMTIE 1600
                    +D  I             +R+       P PT        +  G  + E+ I 
Sbjct: 14964 IKVDVKFKDTVI-------LKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIA 15016

Query: 1601  GLQPTV---------EYVVSVYAQNPSGESQPLVQTAVTNIDRP----KGLAFTDVDVDS 1647
                  +             ++ A NP G ++ +    V  +DRP      LA T+V  + 
Sbjct: 15017 DFSTNLVNKDSTRRDSGAYTLTATNPGGFAKHIFNVKV--LDRPGPPEGPLAVTEVTSEK 15074

Query: 1648  IKIAWESP---QGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVA 1704
               ++W  P    G    + +        +     A + +    ++  L  G+EY   V+A
Sbjct: 15075 CVLSWFPPLDDGGAKIDHYIVQKRETSRLAWTNVASEVQVTKLKVTKLLKGNEYIFRVMA 15134

Query: 1705  LH-----DDMESQPLIGTQSTAIP-APTDLKFTQVTPTSLSAQWTPPN----VQLTGYRV 1754
             ++     + +ES+P++       P  P + + T +T  S+   W  P+     ++  Y V
Sbjct: 15135 VNKYGVGEPLESEPVLAVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEIINYIV 15194

Query: 1755  RVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYA-----LKDTLTSRPAQGVVT 1809
                 K     +K            VSGL    +YE  + A     +     + P      
Sbjct: 15195 ERRDKAGQRWIKCNKKTLTDLRYKVSGLTEGHEYEFRIMAENAAGISAPSPTSPFYKACD 15254

Query: 1810  TLENVSPPRRARVTDATETTITISWRTKT----ETITGFQVD-AVPANGQTPIQRTIKP- 1863
             T+    PP   RV D + ++I+I+W          ITG+ V+ A+P   +  I   + P 
Sbjct: 15255 TVFKPGPPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQI---VTPP 15311

Query: 1864  ---DVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVI 1897
                   SYTITGL    +YKI +Y +N      P ++
Sbjct: 15312 AGLKATSYTITGLTENQEYKIRIYAMNSEGLGEPALV 15348



 Score =  101 bits (252), Expect = 7e-21
 Identities = 270/1291 (20%), Positives = 463/1291 (35%), Gaps = 206/1291 (15%)

Query: 866   TLSDLQPGVQYNITIYAVEENQEST-PVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVT 924
             T++ L  G +Y   + A  EN+  T P    +      + D    P   +  +V+  ++T
Sbjct: 11859 TVTRLIEGNEYIFRVRA--ENKIGTGPPTESKPVIAKTKYDKPGRPDPPEVTKVSKEEMT 11916

Query: 925   IMWTPPE----SAVTGYRVDVIPVNLPGEHGQR-LPISRNTFAE----VTGLSPGVTYYF 975
             ++W PPE     ++TGY ++        +H  R +P++++   E    V  L P   Y F
Sbjct: 11917 VVWNPPEYDGGKSITGYFLEK-----KEKHSTRWVPVNKSAIPERRMKVQNLLPDHEYQF 11971

Query: 976   KVFAVSH------GRESKPLTAQQTTKLDAP-TNLQFVNETDSTVLVRWTPP----RAQI 1024
             +V A +          S+P+ A+   +   P TN + V+ T  ++ + W  P     A I
Sbjct: 11972 RVKAENEIGIGEPSLPSRPVVAKDPIEPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAPI 12031

Query: 1025  TGY------RLTVGLTRRGQPRQYNVGPSVSK-YPLRNLQPASEYTVSL-----VAIKGN 1072
              GY      ++       G  R       V K + + +L    EY   +     V I   
Sbjct: 12032 IGYVVEMRPKIADASPDEGWKRCNAAAQLVRKEFTVTSLDENQEYEFRVCAQNQVGIGRP 12091

Query: 1073  QESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWT-------------PAPRIGFKLGV 1119
              E  +A      L+P    P  + + +   +VI                PAP++ ++   
Sbjct: 12092 AELKEAIKPKEILEP----PEIDLDASMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVG 12147

Query: 1120  RPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTN 1179
               +   +   ++      +V+   T      Y++ ++    E+   +  +V+    P ++
Sbjct: 12148 IDNVVRKGQVDLVDTMAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFVNVRVLDTPGPVSD 12207

Query: 1180  LHLEANPDTGVLTVSW---ERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDN 1236
             L +     T    VSW   E      +T Y +     + +  +++   V   ++S    N
Sbjct: 12208 LKVSDVTKTSC-HVSWAPPENDGGSQVTHYIVEKREADRKTWSTVTPEVK--KTSFHVTN 12264

Query: 1237  LSPGLEYNVSVYTVKDDKESVP--ISDTIIPAVP-----PPTDLRFTNIGPDTMRVTWAP 1289
             L PG EY   V  V +    VP  +   ++ + P     PP  L  T +  ++  + W P
Sbjct: 12265 LVPGNEYYFRVTAVNEYGPGVPTDVPKPVLASDPLSEPDPPRKLEVTEMTKNSATLAWLP 12324

Query: 1290  P---PSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHE 1346
             P       +  ++  Y   +   D         D ++V+T L  G +Y   V++      
Sbjct: 12325 PLRDGGAKIDGYITSYREEEQPADRWTEYSVVKDLSLVVTGLKEGKKYKFRVAARNAVGV 12384

Query: 1347  STPLRGR----QKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPR 1402
             S P         K  L  P  +    IT  +             G ++R    H  G+P 
Sbjct: 12385 SLPREAEGVYEAKEQLLPPKILMPEQITIKA-------------GKKLRIEA-HVYGKPH 12430

Query: 1403  --------EDRV----------PHSRNSITLTNLTPGTEYVVSIVALNGR----EESPLL 1440
                     ED V            S + + + ++T       S+ A N      ++  ++
Sbjct: 12431 PTCKWKKGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVV 12490

Query: 1441  IGQQSTVSDVPRDLEVVAATPTSLLISWDAP----AVTVRYYRITYGETGGNSPVQEFTV 1496
             +         P D+  + A   SL  SW  P       +  Y +   +      V     
Sbjct: 12491 VMDAPGPPQPPFDISDIDADACSL--SWHIPLEDGGSNITNYIVEKCDVSRGDWVTALAS 12548

Query: 1497  PGSKSTATISGLKPGVDYTITVYAVTGRGDS-PASSKPISINYRTEI-DKPSQMQVTDVQ 1554
               +K++  +  L PG +Y   V A    G S P +S  +   +   +  +P   +VT V 
Sbjct: 12549 V-TKTSCRVGKLIPGQEYIFRVRAENRFGISEPLTSPKMVAQFPFGVPSEPKNARVTKVN 12607

Query: 1555  DNSISVKW-LPSS---SPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVV 1610
              + I V W  P S   SP+ GY +    +N     K        TE    GL   +EY  
Sbjct: 12608 KDCIFVAWDRPDSDGGSPIIGYLIERKERNSLLWVKANDTLVRSTEYPCAGLVEGLEYSF 12667

Query: 1611  SVYAQNPSGESQPLVQTAVTN----IDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTY 1666
              +YA N +G S P   T        +D P      DV   ++ + W  P+       + Y
Sbjct: 12668 RIYALNKAGSSPPSKPTEYVTARMPVDPPGKPEVIDVTKSTVSLIWARPKHDGGSKIIGY 12727

Query: 1667  -----SSPEDGIHELFPAPDG---EEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQ 1718
                    P D       AP     EE TA   GL   ++Y    +A      S P     
Sbjct: 12728 FVEACKLPGDKWVRCNTAPHQIPQEEYTAT--GLEEKAQYQFRAIARTAVNISPP----- 12780

Query: 1719  STAIPAPTDLKFTQVTPTSLSAQWTPPNVQLT-GYRVRVTPKEKTG----------PMKE 1767
                   P+D       P ++ A+  PP + L+   +  +T K  T           PM  
Sbjct: 12781 ----SEPSD-------PVTILAENVPPRIDLSVAMKSLLTVKAGTNVCLDATVFGKPMPT 12829

Query: 1768  INLAPDSSSVV-VSGLMVATKYEVSVYAL-----KD----TLTSRPAQGV------VTTL 1811
             ++   D + +    G+ +A +  +    L     KD    T+T+  + G       +  L
Sbjct: 12830 VSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTITAENSSGSKSATIKLKVL 12889

Query: 1812  ENVSPPRRARVTDATETTITISWRTKTET----ITGFQVDAVPANGQTPIQRTIKPDVRS 1867
             +   PP   ++         +SW    E     IT + VD    +     Q +    + S
Sbjct: 12890 DKPGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYIVDKRETSRPNWAQVSATVPITS 12949

Query: 1868  YTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTA---IDAPSNLR---FLATTPNSLLV 1921
              ++  L  G +Y+  +   N      PV  + + A    D P           T + + V
Sbjct: 12950 CSVEKLIEGHEYQFRICAENKYGVGDPVFTEPAIAKNPYDPPGRCDPPVISNITKDHMTV 13009

Query: 1922  SWQPPR----ARITGYIIKYEKPGSPPREVVPRPRPGVTEATI--TGLEPGTEYTIYVIA 1975
             SW+PP     + ITGY++  EK  +         R  + E T+  TGL+ GTEY   V A
Sbjct: 13010 SWKPPADDGGSPITGYLL--EKRETQAVNWTKVNRKPIIERTLKATGLQEGTEYEFRVTA 13067

Query: 1976  LKNNQKSEPLIGRKKTVQKTPFVTHPGYDTG 2006
             +    K+ P  G+     K  +   P Y  G
Sbjct: 13068 I---NKAGP--GKPSDASKAAYARDPQYPPG 13093



 Score =  101 bits (252), Expect = 7e-21
 Identities = 308/1501 (20%), Positives = 533/1501 (35%), Gaps = 204/1501 (13%)

Query: 624   NSHPIQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNS--YTIKGLKPGVVYE 678
             NS  + W  P+    S I +YIL  R K S  RW +      ++   + + GL  G  YE
Sbjct: 21669 NSITLTWARPESDGGSEIQQYILERREKKST-RWVKVISKRPISETRFKVTGLTEGNEYE 21727

Query: 679   GQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVV 738
               +++    G    +           PV          P  P V     VT+ + ++  +
Sbjct: 21728 FHVMAENAAGVGPASGIS-RLIKCREPVNP--------PGPPTVV---KVTDTSKTTVSL 21775

Query: 739   SW----VSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQIS 794
              W          + G+ +E   ++ GD  +        T   + DL  G +Y   V  I+
Sbjct: 21776 EWSKPVFDGGMEIIGYIIEMCKADLGDWHKVNAEACVKTRYTVTDLQAGEEYKFRVSAIN 21835

Query: 795   EDGEQSLILSTSQTTAPD--APPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGS 852
               G+      T    A D    P+  +D     + VVR          Y+   +P+   S
Sbjct: 21836 GAGKGDSCEVTGTIKAVDRLTAPELDIDANFKQTHVVRAGASIRLFIAYQGRPTPTAVWS 21895

Query: 853   STELNLPETANSVTLSDLQPGVQYNIT-------IYAVEENQESTPVVIQQETTGTPRSD 905
               + NL   A+  T          N            VE N  S  +    +   TP   
Sbjct: 21896 KPDSNLSLRADIHTTDSFSTLTVENCNRNDAGKYTLTVENNSGSKSITFTVKVLDTPGP- 21954

Query: 906   TVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPGEHGQRLPISRNTF 961
                 P  + F +VT    T+MW  P     + +  Y V+    +           +R  F
Sbjct: 21955 ----PGPITFKDVTRGSATLMWDAPLLDGGARIHHYVVEKREASRRSWQVISEKCTRQIF 22010

Query: 962   AEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQ----TTKLDAPTNLQFVNETDSTVLVRW 1017
              +V  L+ GV YYF+V AV+     +P    +    T +   P  L  V+ + S+ ++ W
Sbjct: 22011 -KVNDLAEGVPYYFRVSAVNEYGVGEPYEMPEPIVATEQPAPPRRLDVVDTSKSSAVLAW 22069

Query: 1018  TPP----RAQITGYRLTVGLTRRGQPRQYNVGPSVS-KYPLRNLQPASEY---------- 1062
               P     ++ITGY L   + ++G       G +    + +  L   +EY          
Sbjct: 22070 LKPDHDGGSRITGYLLE--MRQKGSDFWVEAGHTKQLTFTVERLVEKTEYEFRVKAKNDA 22127

Query: 1063  -------TVSLVAIKGNQESPKA--TGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRI 1113
                      S V IK  Q  P A  TG+   L    +  P+  +V      I+  PAP++
Sbjct: 22128 GYSEPREAFSSVIIKEPQIEPTADLTGITNQLITCKAGSPFTIDVP-----ISGRPAPKV 22182

Query: 1114  GFKL-GVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVT 1172
              +KL  +R  +        T D  ++ V     G    Y + +      +   +   V+ 
Sbjct: 22183 TWKLEEMRLKETDRVSITTTKDRTTLTVKDSMRGDSGRYFLTLENTAGVKTFSVTVVVIG 22242

Query: 1173  PLSPPTNLHLEANPDTGVLTVSW---ERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQ 1229
                P T     ++       +SW   +     +IT Y +    +       +   V   Q
Sbjct: 22243 RPGPVTGPIEVSSVSAESCVLSWGEPKDGGGTEITNYIVEKRESGTTAWQLVNSSVKRTQ 22302

Query: 1230  SSCTFDNLSPGLEYNVSV-----YTVKDDKESVPISDTIIPAVPP--PTDLRFTNIGPDT 1282
                T  +L+  +EY+  V     + V    ES PI     P VPP  PT     ++  + 
Sbjct: 22303 IKVT--HLTKYMEYSFRVSSENRFGVSKPLESAPII-AEHPFVPPSAPTRPEVYHVSANA 22359

Query: 1283  MRVTWAPPPSIDLTNFLVRYSPVKNEED----VAELSISPSDNAVVLTNLLPGTE----- 1333
             M + W  P   D  + ++ Y   K E +    V E  +   +    +T L+ G E     
Sbjct: 22360 MSIRWEEPYH-DGGSKIIGYWVEKKERNTILWVKENKVPCLECNYKVTGLVEGLEYQFRT 22418

Query: 1334  YVVSVSSVYEQHE-STPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPR----ATITGY 1388
             Y ++ + V +  E S P+  +    +D+P   + +D+T ++ ++ W AP     + + GY
Sbjct: 22419 YALNAAGVSKASEASRPIMAQNP--VDAPGRPEVTDVTRSTVSLIWSAPAYDGGSKVVGY 22476

Query: 1389  RIRHHPEHFSGRPREDRVPH---SRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQS 1445
              I   P    G  R  +  +   S N  T+T L+ G  Y   ++A N      +  G +S
Sbjct: 22477 IIERKPVSEVGDGRWLKCNYTIVSDNFFTVTALSEGDTYEFRVLAKNA--AGVISKGSES 22534

Query: 1446  TVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATI 1505
             T     RD            +  D   +      +     GG    +     G K     
Sbjct: 22535 TGPVTCRDEYAPPKAELDARLHGDLVTIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLC 22594

Query: 1506  SGLKPGVDYT----ITVYAVTGRGDS---------PASSKPISINYRTEIDKP---SQMQ 1549
                K  + YT      V     R DS          + +K +S+  +  +D P    ++ 
Sbjct: 22595 E--KVSLQYTGKRATAVIKFCDRSDSGKYTLTVKNASGTKAVSVMVKV-LDSPGPCGKLT 22651

Query: 1550  VTDVQDNSISVKW-LP---SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPT 1605
             V+ V     ++ W LP     + +T Y V           + +T+  +   + +EG  PT
Sbjct: 22652 VSRVTQEKCTLAWSLPQEDGGAEITHYIV----------ERRETSRLNW--VIVEGECPT 22699

Query: 1606  VEYVVS-----------VYAQNPSG-----ESQPLVQTAVTNIDRPKGL-AFTDVDVDSI 1648
             + YVV+           V A N  G     ES+P+V      I  P G+        + I
Sbjct: 22700 LSYVVTRLIKNNEYIFRVRAVNKYGPGVPVESEPIVARNSFTIPSPPGIPEEVGTGKEHI 22759

Query: 1649  KIAWESPQ----GQVSRYRVTYSSPED----GIHELFPAPDGEEDTAELQGLRPGSEYTV 1700
              I W  P+     ++S Y V     +      +++ +   D      ++  L  G +Y  
Sbjct: 22760 IIQWTKPESDGGNEISNYLVDKREKKSLRWTRVNKDYVVYD---TRLKVTSLMEGCDYQF 22816

Query: 1701  SVVALHDDMESQP------LIGTQSTAIPAPTDL-KFTQVTPTSLSAQWTPP----NVQL 1749
              V A++    S+P      +   + +  P P    +    T  S+S  WT P       +
Sbjct: 22817 RVTAVNAAGNSEPSEASNFISCREPSYTPGPPSAPRVVDTTKHSISLAWTKPMYDGGTDI 22876

Query: 1750  TGYRVRVTPKEKTGPMK-EINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGV- 1807
              GY + +  K+     +   N    ++   V  L +  KY   V A+     S  ++ + 
Sbjct: 22877 VGYVLEMQEKDTDQWYRVHTNATIRNTEFTVPDLKMGQKYSFRVAAVNVKGMSEYSESIA 22936

Query: 1808  -VTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPA-----NGQTPIQRTI 1861
              +  +E +  P    + D  + T+TI        +        P       G     R I
Sbjct: 22937 EIEPVERIEIP-DLELADDLKKTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAI 22995

Query: 1862  KPDVRSYTITGLQPGTDYKIYLYTL---NDNARSSPVVIDASTAIDAP-SNLRFLATTPN 1917
                  SY++  +     Y    YT+   N + + S  V+        P  +++    + +
Sbjct: 22996 IDTTESYSLLIVDKVNRYDAGKYTIEAENQSGKKSATVLVKVYDTPGPCPSVKVKEVSRD 23055

Query: 1918  SLLVSWQPPR----ARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYV 1973
             S+ ++W+ P     A +  YI++  +      + V   +   T   I+GL  GT Y   V
Sbjct: 23056 SVTITWEIPTIDGGAPVNNYIVEKREAAMRAFKTV-TTKCSKTLYRISGLVEGTMYYFRV 23114

Query: 1974  I 1974
             +
Sbjct: 23115 L 23115



 Score =  101 bits (252), Expect = 7e-21
 Identities = 364/1780 (20%), Positives = 631/1780 (35%), Gaps = 317/1780 (17%)

Query: 624   NSHPIQWNAPQPSHISKYILRW---RPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQ 680
             N+  I+W  P     SK I  W   + +N++   KE  +P    +Y + GL  G+ Y+ +
Sbjct: 22358 NAMSIRWEEPYHDGGSKIIGYWVEKKERNTILWVKENKVPCLECNYKVTGLVEGLEYQFR 22417

Query: 681   LISIQQYGHQEVTRFDFTTTSTSTPVTS-NTVTGETTPFSPLVATSESVTEITASSFVVS 739
               ++   G  + +         S P+ + N V     P          VT++T S+  + 
Sbjct: 22418 TYALNAAGVSKASE-------ASRPIMAQNPVDAPGRP---------EVTDVTRSTVSLI 22461

Query: 740   WVSAS----DTVSGFRVEYELSEEGDEPQYLDLPSTATSVN---IPDLLPGRKYIVNVYQ 792
             W + +      V G+ +E +   E  + ++L    T  S N   +  L  G  Y   V  
Sbjct: 22462 WSAPAYDGGSKVVGYIIERKPVSEVGDGRWLKCNYTIVSDNFFTVTALSEGDTYEFRVLA 22521

Query: 793   ISEDGEQSLILSTSQTTAPD------APPDPTVD-QVDDTSIVVRWSRPQAPITGYRIVY 845
              +  G   +I   S++T P       APP   +D ++    + +R         G  +V 
Sbjct: 22522 KNAAG---VISKGSESTGPVTCRDEYAPPKAELDARLHGDLVTIR--------AGSDLVL 22570

Query: 846   SPSVEGS----------STELNLPETANS----------VTLSDLQPGVQYNITIYAVEE 885
               +V G             EL+L E  +           +   D     +Y +T+     
Sbjct: 22571 DAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSGKYTLTVKNASG 22630

Query: 886   NQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDV 941
              +  + +V   ++ G     TV          VT  K T+ W+ P+    + +T Y V+ 
Sbjct: 22631 TKAVSVMVKVLDSPGPCGKLTVS--------RVTQEKCTLAWSLPQEDGGAEITHYIVE- 22681

Query: 942   IPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYY-----------FKVFAVS-HGR----E 985
                        R   SR  +  V G  P ++Y            F+V AV+ +G     E
Sbjct: 22682 -----------RRETSRLNWVIVEGECPTLSYVVTRLIKNNEYIFRVRAVNKYGPGVPVE 22730

Query: 986   SKPLTAQQTTKLDAPTNL-QFVNETDSTVLVRWTPPRA----QITGYRLTVGLTRRGQPR 1040
             S+P+ A+ +  + +P  + + V      ++++WT P +    +I+ Y   V    +   R
Sbjct: 22731 SEPIVARNSFTIPSPPGIPEEVGTGKEHIIIQWTKPESDGGNEISNY--LVDKREKKSLR 22788

Query: 1041  QYNVGPSVSKYPLR----NLQPASEYTVSLVAIK--GNQESPKATGVFTTLQPGSSI-PP 1093
                V      Y  R    +L    +Y   + A+   GN E  +A+   +  +P  +  PP
Sbjct: 22789 WTRVNKDYVVYDTRLKVTSLMEGCDYQFRVTAVNAAGNSEPSEASNFISCREPSYTPGPP 22848

Query: 1094  YNTEVTETT---IVITWTP------APRIGFKLGVRPSQGGEAPR---EVTSDSGSIVVS 1141
                 V +TT   I + WT          +G+ L ++     +  R     T  +    V 
Sbjct: 22849 SAPRVVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDTDQWYRVHTNATIRNTEFTVP 22908

Query: 1142  GLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPD---TGVLTVSWERS 1198
              L  G +Y + +  +      +       + P+       LE   D   T  +       
Sbjct: 22909 DLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEIPDLELADDLKKTVTIRAGASLR 22968

Query: 1199  TTPDITGYRITTTPTNGQQGNSLEEVVHADQS-SCTFDNLSPGLEYNVSVYTVKDDKESV 1257
                 ++G R     T  +QG  L      D + S +   +     Y+   YT++ + +S 
Sbjct: 22969 LMVSVSG-RPPPVITWSKQGIDLASRAIIDTTESYSLLIVDKVNRYDAGKYTIEAENQSG 23027

Query: 1258  PISDTIIPAV----PPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAE 1313
               S T++  V     P   ++   +  D++ +TW  P +ID    +  Y   K E  +  
Sbjct: 23028 KKSATVLVKVYDTPGPCPSVKVKEVSRDSVTITWEIP-TIDGGAPVNNYIVEKREAAMRA 23086

Query: 1314  ---LSISPSDNAVVLTNLLPGTEYVVSV--SSVY---EQHESTPLRGRQKTGLDSPTGID 1365
                ++   S     ++ L+ GT Y   V   ++Y   E  E++      +  L  P  ++
Sbjct: 23087 FKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYGIGEPCETSDAVLVSEVPL-VPAKLE 23145

Query: 1366  FSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRNSI---TLTNL 1418
               D+T ++ T+ W  P     + +TGY +       +G  R  +V   + ++   T+T+L
Sbjct: 23146 VVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACK---AGTERWMKVVTLKPTVLEHTVTSL 23202

Query: 1419  TPGTEYVVSIVALNGREESPLLIGQQSTVSDVP-RDLEVVAATPTSLLISWDAPAVTVRY 1477
               G +Y+  I A N +  S      + TV+ V  +DL V+     S +          R 
Sbjct: 23203 NEGEQYLFRIRAQNEKGVSE----PRETVTAVTVQDLRVLPTIDLSTMPQKTIHVPAGRP 23258

Query: 1478  YRITYGETGGNSPVQEFTVPGSKS-----------------TATISGLKPGVDYTITVYA 1520
               +     G   P   +   GSK                  T   + ++   +YT+ +  
Sbjct: 23259 VELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAKLTIRETTIRDTGEYTLELKN 23318

Query: 1521  VTGRGDSPASSKPISINYRTEIDKPSQ----MQVTDVQDNSISVKWLP----SSSPVTGY 1572
             VTG      +S+ I +     +DKP      +++ ++   SI++ W P      +P++GY
Sbjct: 23319 VTG-----TTSETIKVII---LDKPGPPTGPIKIDEIDATSITISWEPPELDGGAPLSGY 23370

Query: 1573  RVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPL------VQ 1626
              V     + PG      +    T      L    EYV  V A N  G    L       +
Sbjct: 23371 VVEQRDAHRPGWLPVSESVTRST-FKFTRLTEGNEYVFRVAATNRFGIGSYLQSEVIECR 23429

Query: 1627  TAVTNIDRPKGLAFTDVDVDSIKIAWESPQ----GQVSRYRVTYSSPEDGIHELFPAPDG 1682
             +++     P+ L   DV  D + + W  P+     QV+ Y V                  
Sbjct: 23430 SSIRIPGPPETLQIFDVSRDGMTLTWYPPEDDGGSQVTGYIVERKEVRADRWVRVNKVPV 23489

Query: 1683  EEDTAELQGLRPGSEYTVSVVALH------DDMESQPLIGTQSTAIPA-PTDLKFTQVTP 1735
                     GL  G EY   V A++          S+P++     A P  P + + T  T 
Sbjct: 23490 TMTRYRSTGLTEGLEYEHRVTAINARGSGKPSRPSKPIVAMDPIAPPGKPQNPRVTDTTR 23549

Query: 1736  TSLSAQWTPPNVQ----LTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVS 1791
             TS+S  W+ P  +    +TGY + +   ++    K            ++ L    +Y   
Sbjct: 23550 TSVSLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTKCNTTPTKIREYTLTHLPQGAEYRFR 23609

Query: 1792  VYALKDTLTSRPAQ--GVVTTLENVSPP---------RRARVTDATETTITISWRTKTET 1840
             V A        PA+  G V   E +  P             V       +TI  + K   
Sbjct: 23610 VLACNAGGPGEPAEVPGTVKVTEMLEYPDYELDERYQEGIFVRQGGVIRLTIPIKGKP-- 23667

Query: 1841  ITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGT--DYKIYLYTLNDNARSSPVVID 1898
                F +      GQ   +R +     ++T   ++     D   Y   L +      V I 
Sbjct: 23668 ---FPICKWTKEGQDISKRAMIATSETHTELVIKEADRGDSGTYDLVLENKCGKKAVYIK 23724

Query: 1899  ASTAIDAPSN----LRFLATTPNSLLVSWQPPR----ARITGYII-KYEKPGSPPREVVP 1949
                 I +P++    L +      S+ VSW+PP     A I GYI+ + E P +    +  
Sbjct: 23725 VRV-IGSPNSPEGPLEYDDIQVRSVRVSWRPPADDGGADILGYILERREVPKAAWYTIDS 23783

Query: 1950  RPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQKTPFVTHPGYDTGNGI 2009
             R R   T   + GL+   EY   V A      S+PL   +    KTP             
Sbjct: 23784 RVRG--TSLVVKGLKENVEYHFRVSAENQFGISKPLKSEEPVTPKTPL------------ 23829

Query: 2010  QLPGTSGQQPSVGQQMIFEEHGFRRTTPPTTATPIRHRPRPYPPNVGQEALSQTTISWAP 2069
                                        PP         P   PP V     S  ++SW+ 
Sbjct: 23830 --------------------------NPP--------EPPSNPPEVLDVTKSSVSLSWSR 23855

Query: 2070  FQD-----TSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKD--- 2121
              +D      + Y I      TD+     +   T+T  T+TGL   A Y   + A  D   
Sbjct: 23856 PKDDGGSRVTGYYIERKETSTDKWVRHNKTQITTTMYTVTGLVPDAEYQFRIIAQNDVGL 23915

Query: 2122  QQRHKVREEVVTVGNSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLG 2181
              +     E VV       +  ++P+     +  ++S  +V  +WE+    G K   + LG
Sbjct: 23916 SETSPASEPVV-----CKDPFDKPSQPGELEILSISKDSVTLQWEKPECDGGK---EILG 23967

Query: 2182  FGSGHFRCDSSRWCHDNGVNYKIGEKWDRQGENGQMMSCT 2221
             +   + +   S W   N    K     D+Q   G ++  T
Sbjct: 23968 YWVEYRQSGDSAWKKSNKERIK-----DKQFTIGGLLEAT 24002



 Score = 99.8 bits (247), Expect = 3e-20
 Identities = 305/1551 (19%), Positives = 537/1551 (34%), Gaps = 252/1551 (16%)

Query: 610   GPVEVFITETPSQPNSHPIQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSY 666
             GPV        ++ + H + W  P+    S ++ YI+  R  +    W   T      S+
Sbjct: 12203 GPVSDLKVSDVTKTSCH-VSWAPPENDGGSQVTHYIVEKREADRK-TWSTVTPEVKKTSF 12260

Query: 667   TIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSE 726
              +  L PG  Y  ++ ++ +YG           T    PV ++    E  P   L     
Sbjct: 12261 HVTNLVPGNEYYFRVTAVNEYG-------PGVPTDVPKPVLASDPLSEPDPPRKL----- 12308

Query: 727   SVTEITASSFVVSWV----SASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLP 782
              VTE+T +S  ++W+         + G+   Y   E+  +           S+ +  L  
Sbjct: 12309 EVTEMTKNSATLAWLPPLRDGGAKIDGYITSYREEEQPADRWTEYSVVKDLSLVVTGLKE 12368

Query: 783   GRKY-----IVNVYQISEDGEQSLILSTSQTTAPD---APPDPTVDQVDDTSIVVRWSRP 834
             G+KY       N   +S   E   +    +   P     P   T+       I       
Sbjct: 12369 GKKYKFRVAARNAVGVSLPREAEGVYEAKEQLLPPKILMPEQITIKAGKKLRIEAHVYGK 12428

Query: 835   QAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDL--QPGVQYNITIYAVEENQESTPV 892
               P   ++      V  S   ++  ++++ + + D+  +    Y++T             
Sbjct: 12429 PHPTCKWKKGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIK 12488

Query: 893   VIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPG 948
             V+  +  G P+      P D+  ++      ++ W  P     S +T Y V+   V+  G
Sbjct: 12489 VVVMDAPGPPQ-----PPFDISDIDAD--ACSLSWHIPLEDGGSNITNYIVEKCDVS-RG 12540

Query: 949   EHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKL------DAPTN 1002
             +    L     T   V  L PG  Y F+V A +    S+PLT+ +            P N
Sbjct: 12541 DWVTALASVTKTSCRVGKLIPGQEYIFRVRAENRFGISEPLTSPKMVAQFPFGVPSEPKN 12600

Query: 1003  LQFVNETDSTVLVRWTPPRAQ----ITGYRLTVGLTRRGQPRQYNVGPSV---SKYPLRN 1055
              +        + V W  P +     I GY   +    R          ++   ++YP   
Sbjct: 12601 ARVTKVNKDCIFVAWDRPDSDGGSPIIGY--LIERKERNSLLWVKANDTLVRSTEYPCAG 12658

Query: 1056  LQPASEYTVSLVAIKGNQESP--KATGVFTTLQPGSSIPPYNTE---VTETTIVITWT-P 1109
             L    EY+  + A+     SP  K T   T   P    PP   E   VT++T+ + W  P
Sbjct: 12659 LVEGLEYSFRIYALNKAGSSPPSKPTEYVTARMPVD--PPGKPEVIDVTKSTVSLIWARP 12716

Query: 1110  APRIGFKL-----------GVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVY------- 1151
                 G K+           G +  +   AP ++  +      +GL    +Y +       
Sbjct: 12717 KHDGGSKIIGYFVEACKLPGDKWVRCNTAPHQIPQE--EYTATGLEEKAQYQFRAIARTA 12774

Query: 1152  -------------TIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANP-DTGVLTVSWER 1197
                          TI         D  +  K +  +   TN+ L+A      + TVSW++
Sbjct: 12775 VNISPPSEPSDPVTILAENVPPRIDLSVAMKSLLTVKAGTNVCLDATVFGKPMPTVSWKK 12834

Query: 1198  STTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFD----NLSPGLEYNVSVYTVKDD 1253
               T           P  G +       +   ++ CT +    N     +Y ++       
Sbjct: 12835 DGT--------LLKPAEGIK-------MAMQRNLCTLELFSVNRKDSGDYTITAENSSGS 12879

Query: 1254  KESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPP---PSIDLTNFLVRYSPVKNEED 1310
             K S  I   ++    PP  ++   +  D   ++W PP      ++TN++V      +  +
Sbjct: 12880 K-SATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYIVDKRET-SRPN 12937

Query: 1311  VAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPL---RGRQKTGLDSPTGID-- 1365
              A++S +    +  +  L+ G EY   + +  +     P+       K   D P   D  
Sbjct: 12938 WAQVSATVPITSCSVEKLIEGHEYQFRICAENKYGVGDPVFTEPAIAKNPYDPPGRCDPP 12997

Query: 1366  -FSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTP 1420
               S+IT +  TV W  P     + ITGY +           + +R P    ++  T L  
Sbjct: 12998 VISNITKDHMTVSWKPPADDGGSPITGYLLEKRETQAVNWTKVNRKPIIERTLKATGLQE 13057

Query: 1421  GTEYVVSIVALNGREESPLLIGQQSTVSDV------------PRDLEVVAATPTSLLISW 1468
             GTEY   + A+N  +  P   G+ S  S              P   +V   T +S+ +SW
Sbjct: 13058 GTEYEFRVTAIN--KAGP---GKPSDASKAAYARDPQYPPGPPAFPKVYDTTRSSVSLSW 13112

Query: 1469  DAPAV----TVRYYRITYGETGGNSPVQEFTVPGS--KSTATISGLKPGVDYTITVYAVT 1522
               PA      +  Y +       ++ V+   +P +  K+   ++GL     Y   VYAV 
Sbjct: 13113 GKPAYDGGSPIIGYLVEVKRADSDNWVR-CNLPQNLQKTRFEVTGLMEDTQYQFRVYAVN 13171

Query: 1523  GRG-----DSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTT 1577
               G     D P    P  I    E +  + ++ T +    ++++      PV G      
Sbjct: 13172 KIGYSDPSDVPDKHYPKDILIPPEGELDADLRKTLILRAGVTMRLY---VPVKGRPPPKI 13228

Query: 1578  PKNGPGPTKTKTAGPD------QTEMTIEGLQ--PTVEYVVSVYAQNPSGESQPLVQTAV 1629
               + P        G D       T +  E +      +Y++++  +N  G+ +  +   V
Sbjct: 13229 TWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKYILTL--ENSCGKKEYTIVVKV 13286

Query: 1630  TNIDRPK-GLAFTDVDVDSIKIAWESP----QGQVSRYRVTYSSPEDGIHELFPAPDGEE 1684
              +   P   +   ++  DS  + WE P       +  Y V     E          +  +
Sbjct: 13287 LDTPGPPVNVTVKEISKDSAYVTWEPPIIDGGSPIINYVVQKRDAERKSWSTV-TTECSK 13345

Query: 1685  DTAELQGLRPGSEYTVSVVA-----LHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLS 1739
              +  +  L  G  Y   V A     + D  E++  +    T  P   DLK   V+ +S S
Sbjct: 13346 TSFRVANLEEGKSYFFRVFAENEYGIGDPGETRDAVKASQTPGPV-VDLKVRSVSKSSCS 13404

Query: 1740  AQWTPPN----VQLTGYRVRVTPKEKTGP--MKEINLAPDSSSVVVSGLMVATKYEVSVY 1793
               W  P+     ++ GY V    +E      MK ++L   +       L    +Y   V 
Sbjct: 13405 IGWKKPHSDGGSRIIGYVVDFLTEENKWQRVMKSLSLQYSAKD-----LTEGKEYTFRVS 13459

Query: 1794  ALKDTLTSRPAQGVVTTLENVSPPR-------------------RARVTDATETTITISW 1834
             A  +     P++  V   ++V  P                    R ++    +   ++SW
Sbjct: 13460 AENENGEGTPSEITVVARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPIKGKPAPSVSW 13519

Query: 1835  RTKTE---TITGFQVDAVPANGQTPIQRTIKPDVRSYTIT-----GLQPGTDYKIYLYTL 1886
             +   +   T T   V++   N    +    K D   YTIT     G + GT         
Sbjct: 13520 KKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKEGT--------- 13570

Query: 1887  NDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGS 1942
                   S  V+        P  ++F   T  ++ + W PP+    + IT YI++ ++   
Sbjct: 13571 -----ISIKVVGKPGIPTGP--IKFDEVTAEAMTLKWAPPKDDGGSEITNYILE-KRDSV 13622

Query: 1943  PPREVVPRPRPGVTEATITGLEPGTEYTIYVIA-----LKNNQKSEPLIGR 1988
               + V        T   +T L  G EYT  V A     +    KSEP++ R
Sbjct: 13623 NNKWVTCASAVQKTTFRVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVAR 13673



 Score = 96.7 bits (239), Expect = 2e-19
 Identities = 334/1533 (21%), Positives = 553/1533 (36%), Gaps = 218/1533 (14%)

Query: 619   TPSQPNSHPIQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGV 675
             T S  +S  +QWN P     S +  Y L  + +NS+   K    P     +   GL+ GV
Sbjct: 15853 TLSSRDSMEVQWNEPISDGGSRVIGYHLERKERNSILWVKLNKTPIPQTKFKTTGLEEGV 15912

Query: 676   VYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASS 735
              YE ++ +    G                P   +       P  P     E++  +T +S
Sbjct: 15913 EYEFRVSAENIVG-------------IGKPSKVSECYVARDPCDP-PGRPEAII-VTRNS 15957

Query: 736   FVVSW----VSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVY 791
               + W          ++G+ VE +   EG   +        T   +  L+   +Y   V 
Sbjct: 15958 VTLQWKKPTYDGGSKITGYIVEKKELPEGRWMKASFTNIIDTHFEVTGLVEDHRYEFRVI 16017

Query: 792   QISEDGEQSLIL-STSQTTAPDA--PPDPTVDQVDDTSIVVRWS---RPQAPITGYRIVY 845
               +  G  S    ST   TA D   PP  ++D     +IVV      +  A I G  I  
Sbjct: 16018 ARNAAGVFSEPSESTGAITARDEVDPPRISMDPKYKDTIVVHAGESFKVDADIYGKPI-- 16075

Query: 846   SPSVEGSSTELNLPETAN-SVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRS 904
              P+++    +  L  TA   +  +D    +     +       +S   +++ +     RS
Sbjct: 16076 -PTIQWIKGDQELSNTARLEIKSTDFATSLSVKDAVRV-----DSGNYILKAKNVAGERS 16129

Query: 905   DTV-------PSPRDLQFV--EVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLP 955
              TV       P P +   V   VT  K T+ W PP   +     D+I   +      RL 
Sbjct: 16130 VTVNVKVLDRPGPPEGPVVISGVTAEKCTLAWKPP---LQDGGSDIINYIVERRETSRLV 16186

Query: 956   IS------RNTFAEVTGLSPGVTYYFKVFAVS-----HGRESKPLTAQQTTKL-DAPTNL 1003
              +      +    +VT L  G  Y F++ AV+        ES+P+ A+    + DAP   
Sbjct: 16187 WTVVDANVQTLSCKVTKLLEGNEYTFRIMAVNKYGVGEPLESEPVVAKNPFVVPDAPKAP 16246

Query: 1004  QFVNETDSTVLVRWTPPRA----QITGYRLTV----GLTRRGQPRQYNVGPSVSKYPLRN 1055
             +    T  +++V W  P +    +I GY L      G+ R  +  +  +G    +     
Sbjct: 16247 EVTTVTKDSMIVVWERPASDGGSEILGYVLEKRDKEGI-RWTRCHKRLIGELRLRVTGLI 16305

Query: 1056  LQPASEYTVSLVAIKGNQE-SPKAT---GVFTTLQPGSSIPPYNTEVTETTIVITWTPAP 1111
                  E+ VS     G  E SP +          +PG    P   ++T +++ ++W+   
Sbjct: 16306 ENHDYEFRVSAENAAGLSEPSPPSAYQKACDPIYKPGPPNNPKVIDITRSSVFLSWSKPI 16365

Query: 1112  RIGF---------KLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRD---G 1159
               G          K  V   +          +  +I V  L    EY + I  +     G
Sbjct: 16366 YDGGCEIQGYIVEKCDVSVGEWTMCTPPTGINKTNIEVEKLLEKHEYNFRICAINKAGVG 16425

Query: 1160  QERDAPIVNKVVTPL-SPPTNLHLEANPDTGV-------LTVSWERSTTPDITGYRITTT 1211
             +  D P    V   L +P  +L LE      +       L V  +   TP++   ++   
Sbjct: 16426 EHADVPGPIIVEEKLEAPDIDLDLELRKIINIRAGGSLRLFVPIKGRPTPEVKWGKV--- 16482

Query: 1212  PTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTV----KDDKESVPISDTIIPAV 1267
               +G+  ++    V +  +S   DN++    Y+   YT+        +S  ++  ++   
Sbjct: 16483 --DGEIRDAAIIDVTSSFTSLVLDNVN---RYDSGKYTLTLENSSGTKSAFVTVRVLDTP 16537

Query: 1268  PPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNE---EDVAELSISPSDNAVV 1324
              PP +L+ T I  D++ +TW  PP +D  + +  Y   K E   +  A +  +   N+  
Sbjct: 16538 SPPVNLKVTEITKDSVSITW-EPPLLDGGSKIKNYIVEKREATRKSYAAVVTNCHKNSWK 16596

Query: 1325  LTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGL----DSPTGIDFSDITANSFTVHWIA 1380
             +  L  G  Y   V++  E     P +      +      P  I   D+T NS ++ W  
Sbjct: 16597 IDQLQEGCSYYFRVTAENEYGIGLPAQTADPIKVAEVPQPPGKITVDDVTRNSVSLSWTK 16656

Query: 1381  PR----ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREE 1436
             P     + I  Y +    +H        RV   +    +TNLT G EY+  +VA+N +  
Sbjct: 16657 PEHDGGSKIIQYIVEMQAKHSEKWSECARVKSLQ--AVITNLTQGEEYLFRVVAVNEKGR 16714

Query: 1437  S-PLLIGQQSTVSDVPRDLEVVAA-TPTSLLISWD----APAVTVRYYRITYGETGGNSP 1490
             S P  +       D+  + +V  A +  S+ +  D     P        IT+ + G   P
Sbjct: 16715 SDPRSLAVPIVAKDLVIEPDVKPAFSSYSVQVGQDLKIEVPISGRPKPTITWTKDG--LP 16772

Query: 1491  VQEFT---VPGSKSTATIS----GLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEID 1543
             +++ T   V  S    T+S        G  Y ITV  V G+       K  SI   T +D
Sbjct: 16773 LKQTTRINVTDSLDLTTLSIKETHKDDGGQYGITVANVVGQ-------KTASIEIVT-LD 16824

Query: 1544  KP----SQMQVTDVQDNSISVKWLP----SSSPVTGYRV-----TTTPKNGPGPTKTKTA 1590
             KP      ++  DV   SI++ W P        +T Y V     TTT  +    T  +T 
Sbjct: 16825 KPDPPKGPVKFDDVSAESITLSWNPPLYTGGCQITNYIVQKRDTTTTVWDVVSATVARTT 16884

Query: 1591  GPDQTEMTIEGLQPTVEYVVSVYAQNPSG-----ESQPLVQTAVTNIDRPKGLAF-TDVD 1644
                   + +  L+   EY   ++A+N  G     ES P+V         P G  F T + 
Sbjct: 16885 ------LKVTKLKTGTEYQFRIFAENRYGQSFALESDPIVAQYPYKEPGPPGTPFATAIS 16938

Query: 1645  VDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGE---EDTA-ELQGLRPGSEYTV 1700
              DS+ I W  P        + Y       + +      +    DT  + Q L  G EY  
Sbjct: 16939 KDSMVIQWHEPVNNGGSPVIGYHLERKERNSILWTKVNKTIIHDTQFKAQNLEEGIEYEF 16998

Query: 1701  SVVALHDDMESQPLIGTQSTAIPAPTDLKFT----QVTPTSLSAQWTPP----NVQLTGY 1752
              V A +     +    ++      P D   T     V    ++ QWT P       +TGY
Sbjct: 16999 RVYAENIVGVGKASKNSECYVARDPCDPPGTPEPIMVKRNEITLQWTKPVYDGGSMITGY 17058

Query: 1753  RVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDT-LTSRPAQ--GVVT 1809
              V          MK        +   VSGL    +YE  V A       S+P+   G +T
Sbjct: 17059 IVEKRDLPDGRWMKASFTNVIETQFTVSGLTEDQRYEFRVIAKNAAGAISKPSDSTGPIT 17118

Query: 1810  TLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYT 1869
               + V  PR +      +T +  +  T       F+++A       P    ++ D     
Sbjct: 17119 AKDEVELPRISMDPKFRDTIVVNAGET-------FRLEADVHGKPLPTIEWLRGDKEIEE 17171

Query: 1870  ITGLQ-PGTDYKIYL------------YTLNDN----ARSSPV---VIDASTAIDAPSNL 1909
                 +   TD+K  L            Y L  +    ++S PV   V+D     + P  +
Sbjct: 17172 SARCEIKNTDFKALLIVKDAIRIDGGQYILRASNVAGSKSFPVNVKVLDRPGPPEGP--V 17229

Query: 1910  RFLATTPNSLLVSWQPP----RARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEP 1965
             +    T     ++W PP     + I+ Y+++ ++  S     V           +T L  
Sbjct: 17230 QVTGVTSEKCSLTWSPPLQDGGSDISHYVVE-KRETSRLAWTVVASEVVTNSLKVTKLLE 17288

Query: 1966  GTEYTIYVIALKNNQKSEPLIGRKKTVQKTPFV 1998
             G EY   ++A+      EPL      + K PFV
Sbjct: 17289 GNEYVFRIMAVNKYGVGEPL-ESAPVLMKNPFV 17320



 Score = 93.6 bits (231), Expect = 2e-18
 Identities = 287/1440 (19%), Positives = 522/1440 (36%), Gaps = 175/1440 (12%)

Query: 675   VVYEGQLISIQQYGHQEVTRFDFTTTSTS--TPVTSNTVTGETT--PFSPLVATSESVTE 730
             +  E   I++++    +  R++ T  ++S  T    N V  +    P  P+V     +++
Sbjct: 20030 ITAENLTINLKESVTADAGRYEITAANSSGTTKAFINIVVLDRPGPPTGPVV-----ISD 20084

Query: 731   ITASSFVVSWVSAS-DTVSGFRVEYELSEEGDEPQYLDLPSTA--TSVNIPDLLPGRKY- 786
             IT  S  + W     D  S       L  E     + ++ +T   T + +  L  G +Y 
Sbjct: 20085 ITEESVTLKWEPPKYDGGSQVTNYILLKRETSTAVWTEVSATVARTMMKVMKLTTGEEYQ 20144

Query: 787   ----IVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYR 842
                   N + IS+  + + +      T P  P  P V  V   SI V W  P +   G  
Sbjct: 20145 FRIKAENRFGISDHIDSACVTVKLPYTTPGPPSTPWVTNVTRESITVGWHEPVS--NGGS 20202

Query: 843   IVYSPSVEGSSTELNLPETANSVTL-------SDLQPGVQYNITIYAVEENQESTPVVIQ 895
              V    +E       L + AN + +       + +  G+ Y   +YA        P    
Sbjct: 20203 AVVGYHLEMKDRNSILWQKANKLVIRTTHFKVTTISAGLIYEFRVYAENAAGVGKP---S 20259

Query: 896   QETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPVNLPGEHG 951
               +      D    PR+++  +++   V++ W  P     S +TGY V+    +LP    
Sbjct: 20260 HPSEPVLAIDACEPPRNVRITDISKNSVSLSWQQPAFDGGSKITGYIVE--RRDLPDGRW 20317

Query: 952   QRLPISRNTFAE--VTGLSPGVTYYFKVFAVSH-GRESKPL-TAQQTTKLDAPTNLQFVN 1007
              +   +  T  +  ++GL+    Y F+VFA +  G  S P       T +D+        
Sbjct: 20318 TKASFTNVTETQFIISGLTQNSQYEFRVFARNAVGSISNPSEVVGPITCIDSYGGPVIDL 20377

Query: 1008  ETDSTVLVRWTPPRAQITGYRLTVGLTRRGQP--RQYNVGPSVSKYPLRNLQPASEYTVS 1065
               + T +V++       T  +L  G++ +  P    Y     +    L  ++  ++    
Sbjct: 20378 PLEYTEVVKYRAG----TSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLASI 20433

Query: 1066  LV-------------AIKGNQESPKATGVFTTL-QPGSSIPPYNTE-VTETTIVITW-TP 1109
             L+              ++    S  AT     L +PG    P   + VT   I + W  P
Sbjct: 20434 LIKDADRLNSGCYELKLRNAMGSASATIRVQILDKPGPPGGPIEFKTVTAEKITLLWRPP 20493

Query: 1110  APRIGFKLGVRPSQGGEAPREVTS------DSGSIVVSGLTPGVEYVYTIQVLR-----D 1158
             A   G K+     +  E  R V S      +   I  + +  G EY++ ++ +      +
Sbjct: 20494 ADDGGAKITHYIVEKRETSRVVWSMVSEHLEECIITTTKIIKGNEYIFRVRAVNKYGIGE 20553

Query: 1159  GQERDAPIV-NKVVTPLSP--PTNLHLEANPDTGVLTVSWERSTT---PDITGYRITTTP 1212
               E D+ +  N  VTP  P  P    +  N     +TV W R       DI+GY +    
Sbjct: 20554 PLESDSVVAKNAFVTPGPPGIPEVTKITKNS----MTVVWSRPIADGGSDISGYFLEKRD 20609

Query: 1213  TNGQQG-NSLEEVVHADQSSCTFDNLSPGLEYNVSVYTV--------KDDKESVPISDTI 1263
                      L+E +   +   T   L+   +Y   V  V         +  E    +D I
Sbjct: 20610 KKSLGWFKVLKETIRDTRQKVT--GLTENSDYQYRVCAVNAAGQGPFSEPSEFYKAADPI 20667

Query: 1264  IPAVPPPTDLRFTNIGPDTMRVTWAPP---PSIDLTNFLVRYSPVKNEE-DVAELSISPS 1319
              P   PP  +R  +    ++ + W+ P       +T ++V     + EE           
Sbjct: 20668 DPP-GPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVVEIRQGEEEEWTTVSTKGEVR 20726

Query: 1320  DNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQ----KTGLDSPTGIDFSDITANSFT 1375
                 V++NL PG  Y   VS+V    +  P+   +    K  L++P  ID       S  
Sbjct: 20727 TTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQAKDILEAPE-IDLDVALRTSVI 20785

Query: 1376  VHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSI---------TLTNLTPGT--EY 1424
                      +  ++ R  P     +  ++    +R SI         T+  +T     +Y
Sbjct: 20786 AKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKY 20845

Query: 1425  VVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGE 1484
             +++I    G  +S  +  +        + L+V   +  ++ + WD P +      I Y  
Sbjct: 20846 ILTIENGVGEPKSSTVSVKVLDTPAACQKLQVKHVSRGTVTLLWDPPLIDGGSPIINYVI 20905

Query: 1485  TGGNSPVQEFTVPGSKSTATISGL-----KPGVDYTITVYAVTGRGDSPASSKPISINYR 1539
                ++  + ++V   K ++T   L     K    + +      G G+   +++P+     
Sbjct: 20906 EKRDATKRTWSVVSHKCSSTSFKLIDLSEKTPFFFRVLAENEIGIGEPCETTEPVK---A 20962

Query: 1540  TEIDKP-SQMQVTDVQDNSISVKW----LPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQ 1594
              E+  P   + + D    S+ + W        S +T Y V    + G G      AG  +
Sbjct: 20963 AEVPAPIRDLSMKDSTKTSVILSWTKPDFDGGSVITEYVV---ERKGKGEQTWSHAGISK 21019

Query: 1595  T-EMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFT-DVDVDSIKIAW 1652
             T E+ +  L+        V+A+N  G S P+    +T     K L  T +VD+  I  A 
Sbjct: 21020 TCEIEVSQLKEQSVLEFRVFAKNEKGLSDPVTIGPIT----VKELIITPEVDLSDIPGAQ 21075

Query: 1653  ESPQ-GQVSRYRVTY-SSPEDGIHEL---FPAPDGE-------EDTAELQGLRPGSEYTV 1700
              + + G      + Y   P+  I  L    P  + E       E+   L       E+  
Sbjct: 21076 VTVRIGHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGG 21135

Query: 1701  SVVALHDDMESQPLIGTQSTAIPAPT----DLKFTQVTPTSLSAQWTPP----NVQLTGY 1752
                 + D+   +  +      +  P+     ++F ++   S+   W  P      ++T Y
Sbjct: 21136 KYTVILDNAVCRIAVPITVITLGPPSKPKGPIRFDEIKADSVILSWDVPEDNGGGEITCY 21195

Query: 1753  RVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLE 1812
              +      +T   K +  +   ++  V  L+   +Y+  V A      S+P    +   +
Sbjct: 21196 SIEKRETSQTN-WKMVCSSVARTTFKVPNLVKDAEYQFRVRAENRYGVSQPLVSSIIVAK 21254

Query: 1813  N----VSPPRRARVTDATETTITISWRTKT----ETITGFQVDAVPANGQTPIQRTIKP- 1863
             +      PP +  + + T   ++++W          +TGF V+    N     +    P 
Sbjct: 21255 HQFRIPGPPGKPVIYNVTSDGMSLTWDAPVYDGGSEVTGFHVEKKERNSILWQKVNTSPI 21314

Query: 1864  DVRSYTITGLQPGTDYKIYLYTLNDNARSSP----VVIDASTAIDAPSNLRFLATTPNSL 1919
               R Y  TGL  G DY+  +Y  N    SSP        A + +D P    ++  T  ++
Sbjct: 21315 SGREYRATGLVEGLDYQFRVYAENSAGLSSPSDPSKFTLAVSPVDPPGTPDYIDVTRETI 21374

Query: 1920  LVSWQPP----RARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIA 1975
              + W PP     ++I GY I+ ++ G+              + T+TGL PG  Y   +IA
Sbjct: 21375 TLKWNPPLRDGGSKIVGYSIE-KRQGNERWVRCNFTDVSECQYTVTGLSPGDRYEFRIIA 21433



 Score = 92.8 bits (229), Expect = 3e-18
 Identities = 271/1344 (20%), Positives = 470/1344 (34%), Gaps = 199/1344 (14%)

Query: 628   IQWNAPQPS---HISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISI 684
             I W  P  +    IS YI+  R   +   W   +      +  I  LK G  Y+ ++ + 
Sbjct: 17927 ISWEPPAYTGGCQISNYIVEKRDTTTT-TWHMVSATVARTTIKITKLKTGTEYQFRIFAE 17985

Query: 685   QQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSAS 744
              +YG              S P+ S  V  +     P    +  VT I+    +V W    
Sbjct: 17986 NRYGK-------------SAPLDSKAVIVQYPFKEPGPPGTPFVTSISKDQMLVQWHEPV 18032

Query: 745   DTVSGFRVEYELSE-EGDEPQYLDLPSTA---TSVNIPDLLPGRKYI--VNVYQISEDGE 798
             +      + Y L + E +   ++ L  T    T      L  G +Y   V+   I   G+
Sbjct: 18033 NDGGTKIIGYHLEQKEKNSILWVKLNKTPIQDTKFKTTGLDEGLEYEFKVSAENIVGIGK 18092

Query: 799   QSLILSTSQTTAPDAPPD-PTVDQVDDTSIVVRWSRPQ----APITGYRIVYSPSVEG-- 851
              S +        P  PP  P    +   ++ ++W +P     + ITGY +      +G  
Sbjct: 18093 PSKVSECFVARDPCDPPGRPEAIVITRNNVTLKWKKPAYDGGSKITGYIVEKKDLPDGRW 18152

Query: 852   -SSTELNLPETANSVTLSDLQPGVQYNITIYA------VEENQESTPVVIQQETTGTPRS 904
               ++  N+ ET    T+S L    +Y   + A        E  +S+  +  ++    P +
Sbjct: 18153 MKASFTNVLET--EFTVSGLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARDEIDAPNA 18210

Query: 905   DTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPG----EHGQRLPISRNT 960
                P  +D+  V   +  V       E+ + G  +  +  +  G    E   R+ I ++T
Sbjct: 18211 SLDPKYKDVIVVHAGETFVL------EADIRGKPIPDVVWSKDGKELEETAARMEI-KST 18263

Query: 961   FAEVTGL------SPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTN-LQFVNETDSTV 1013
               + T +      + G  Y  K+  V  G +S P+T +   +   P   L+    T    
Sbjct: 18264 IQKTTLVVKDCIRTDGGQYILKLSNVG-GTKSIPITVKVLDRPGPPEGPLKVTGVTAEKC 18322

Query: 1014  LVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAI 1069
              + W PP     A I+ Y +    T R    Q +       Y +  L P +EY   ++A+
Sbjct: 18323 YLAWNPPLQDGGANISHYIIEKRETSRLSWTQVSTEVQALNYKVTKLLPGNEYIFRVMAV 18382

Query: 1070  -KGNQESPKATGVFTTLQP----GSSIPPYNTEVTETTIVITWTP------APRIGFKLG 1118
              K     P  +G  T   P    G    P  + +T+ ++V+TW            G+ L 
Sbjct: 18383 NKYGIGEPLESGPVTACNPYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILE 18442

Query: 1119  VRPSQGGEAPR--EVTSDSGSIVVSGLTPGVEYVYTIQVLRD---GQERDAPIVNKVVTP 1173
              R  +G    +  + T     + V+GLT G  Y + +        G+  +  +  +    
Sbjct: 18443 KRDKEGVRWTKCNKKTLTDLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRACDA 18502

Query: 1174  LSPPTNLHLEANPDTGVLTVS--WERSTTPD---ITGYRI-----------TTTPTNGQQ 1217
             L PP         DT   +VS  W +        + GY +           T TP  G Q
Sbjct: 18503 LYPPGPPSNPKVTDTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAADEWTTCTPPTGLQ 18562

Query: 1218  GNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDD----KESVPISDTIIPAVPPP--- 1270
             G              T   L    EYN  +  +  +      ++P S      + PP   
Sbjct: 18563 GKQF-----------TVTKLKENTEYNFRICAINSEGVGEPATLPGSVVAQERIEPPEIE 18611

Query: 1271  --TDLRFTNI--GPDTMR----VTWAPPPSIDLTNFLVRYSPVKNE-EDVAELSISPSDN 1321
                DLR   +     T+R    +   P P        V++   +    D A++ ++ S  
Sbjct: 18612 LDADLRKVVVLRASATLRLFVTIKGRPEPE-------VKWEKAEGILTDRAQIEVTSSFT 18664

Query: 1322  AVVLTNLLPGTEYVVSVSSVYEQHESTP-LRGRQKTGLDSPTGIDFSDITANSFTVHWIA 1380
              +V+ N+        +++        T  +  R      +P  +   ++  +S T+ W  
Sbjct: 18665 MLVIDNVTRFDSGRYNLTLENNSGSKTAFVNVRVLDSPSAPVNLTIREVKKDSVTLSWEP 18724

Query: 1381  PR----ATITGYRIRHHPEHFSGRPREDRVPHS--RNSITLTNLTPGTEYVVSIVALNGR 1434
             P     A IT Y +       + R     + ++  + +  + NL  G  Y   ++A N  
Sbjct: 18725 PLIDGGAKITNYIVEKRE---TTRKAYATITNNCTKTTFRIENLQEGCSYYFRVLASNEY 18781

Query: 1435  EES-PLLIGQQSTVSDVPRD---LEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSP 1490
                 P    +   VS+ P     + +V  T  +  I W+ P            E+ G S 
Sbjct: 18782 GIGLPAETTEPVKVSEPPLPPGRVTLVDVTRNTATIKWEKP------------ESDGGSK 18829

Query: 1491  VQEFTVP----GSKS----------TATISGLKPGVDYTITVYAVTGRGDSPASSKPISI 1536
             +  + V     GS+            ATISGL  G +Y   V AV  +G S      + +
Sbjct: 18830 ITGYVVEMQTKGSEKWSTCTQVKTLEATISGLTAGEEYVFRVAAVNEKGRSDPRQLGVPV 18889

Query: 1537  NYRTEIDKPSQMQVTDVQDNSISVK---WLPSSSPVTGYRVTTTPKNGPGPTKTKT---- 1589
               R    KPS     ++  ++ +VK    L    P  G    T      G T  +T    
Sbjct: 18890 IARDIEIKPS----VELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVN 18945

Query: 1590  --AGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKG-LAFTDVDVD 1646
               +    T ++I+           +   N +G     +   V +   P G +   +V  D
Sbjct: 18946 VSSSKTVTSLSIKEASKEDVGTYELCVSNSAGSITVPITIIVLDRPGPPGPIRIDEVSCD 19005

Query: 1647  SIKIAWESPQ----GQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSV 1702
             SI I+W  P+     Q+S Y V           +  +      + ++  L  GSEY   V
Sbjct: 19006 SITISWNPPEYDGGCQISNYIVEKKETTSTTWHIV-SQAVARTSIKIVRLTTGSEYQFRV 19064

Query: 1703  VALH-----DDMESQPLIGTQSTAIPAPTDL-KFTQVTPTSLSAQWTPP----NVQLTGY 1752
              A +        ES  ++     + P P    K    T +++   W  P      ++ GY
Sbjct: 19065 CAENRYGKSSYSESSAVVAEYPFSPPGPPGTPKVVHATKSTMLVTWQVPVNDGGSRVIGY 19124

Query: 1753  RVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGV--VTT 1810
              +    +      K   +    + + VSGL     YE  VYA       + ++    V  
Sbjct: 19125 HLEYKERSSILWSKANKILIADTQMKVSGLDEGLMYEYRVYAENIAGIGKCSKSCEPVPA 19184

Query: 1811  LENVSPPRRARVTDATETTITISW 1834
              +   PP +  VT+ T  ++++ W
Sbjct: 19185 RDPCDPPGQPEVTNITRKSVSLKW 19208



 Score = 92.0 bits (227), Expect = 6e-18
 Identities = 265/1345 (19%), Positives = 470/1345 (34%), Gaps = 186/1345 (13%)

Query: 814   PPDPTVD--QVDDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTL 867
             PP P  D   +D  +  + W  P     + IT Y +       G         T  S  +
Sbjct: 12497 PPQPPFDISDIDADACSLSWHIPLEDGGSNITNYIVEKCDVSRGDWVTALASVTKTSCRV 12556

Query: 868   SDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPS-PRDLQFVEVTDVKVTIM 926
               L PG +Y   + A      S P+   +     P    VPS P++ +  +V    + + 
Sbjct: 12557 GKLIPGQEYIFRVRAENRFGISEPLTSPKMVAQFPFG--VPSEPKNARVTKVNKDCIFVA 12614

Query: 927   WTPPES----AVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSH 982
             W  P+S     + GY ++    N          + R+T     GL  G+ Y F+++A++ 
Sbjct: 12615 WDRPDSDGGSPIIGYLIERKERNSLLWVKANDTLVRSTEYPCAGLVEGLEYSFRIYALNK 12674

Query: 983   GRESKPL--TAQQTTKL--DAPTNLQFVNETDSTVLVRWTPPR----AQITGYRLTVGLT 1034
                S P   T   T ++  D P   + ++ T STV + W  P+    ++I GY +     
Sbjct: 12675 AGSSPPSKPTEYVTARMPVDPPGKPEVIDVTKSTVSLIWARPKHDGGSKIIGYFVEACKL 12734

Query: 1035  RRGQPRQYNVGPSV---SKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSI 1091
                +  + N  P      +Y    L+  ++Y    +A      SP +           ++
Sbjct: 12735 PGDKWVRCNTAPHQIPQEEYTATGLEEKAQYQFRAIARTAVNISPPSEPSDPVTILAENV 12794

Query: 1092  PP----------YNTEVTETTIVITWT----PAPRIGFKLG---VRPSQGGEAPREVTSD 1134
             PP            T    T + +  T    P P + +K     ++P++G +   +   +
Sbjct: 12795 PPRIDLSVAMKSLLTVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQ--RN 12852

Query: 1135  SGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVS 1194
               ++ +  +       YTI        + A I  KV+    PP ++ +        + +S
Sbjct: 12853 LCTLELFSVNRKDSGDYTITAENSSGSKSATIKLKVLDKPGPPASVKINKMYSDRAM-LS 12911

Query: 1195  WE---RSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVK 1251
             WE        +IT Y +    T+      +   V    +SC+ + L  G EY   +    
Sbjct: 12912 WEPPLEDGGSEITNYIVDKRETSRPNWAQVSATVPI--TSCSVEKLIEGHEYQFRICAEN 12969

Query: 1252  DDKESVPI-SDTIIPAVP--------PPTDLRFTNIGPDTMRVTWAPPPS---IDLTNFL 1299
                   P+ ++  I   P        PP     +NI  D M V+W PP       +T +L
Sbjct: 12970 KYGVGDPVFTEPAIAKNPYDPPGRCDPPV---ISNITKDHMTVSWKPPADDGGSPITGYL 13026

Query: 1300  V--RYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTG 1357
             +  R +   N   V    I   +  +  T L  GTEY   V+++ +     P    +   
Sbjct: 13027 LEKRETQAVNWTKVNRKPII--ERTLKATGLQEGTEYEFRVTAINKAGPGKPSDASKAAY 13084

Query: 1358  LDSP-------TGIDFSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPREDRV 1406
                P             D T +S ++ W  P     + I GY +           R +  
Sbjct: 13085 ARDPQYPPGPPAFPKVYDTTRSSVSLSWGKPAYDGGSPIIGYLVEVKRADSDNWVRCNLP 13144

Query: 1407  PH-SRNSITLTNLTPGTEYVVSIVALNGREES-PLLIGQQSTVSDV--PRDLEVVAATPT 1462
              +  +    +T L   T+Y   + A+N    S P  +  +    D+  P + E+ A    
Sbjct: 13145 QNLQKTRFEVTGLMEDTQYQFRVYAVNKIGYSDPSDVPDKHYPKDILIPPEGELDADLRK 13204

Query: 1463  SLLISWDAPAVTVRYY---------RITYGETGGNSPVQEFTVPGSKSTATISGLKPGVD 1513
             +L++      VT+R Y         +IT+ +   N   +      S    T    +    
Sbjct: 13205 TLILR---AGVTMRLYVPVKGRPPPKITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNK 13261

Query: 1514  YTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLP----SSSPV 1569
             Y    Y +T           I +        P  + V ++  +S  V W P      SP+
Sbjct: 13262 YDAGKYILTLENSCGKKEYTIVVKVLDTPGPPVNVTVKEISKDSAYVTWEPPIIDGGSPI 13321

Query: 1570  TGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAV 1629
               Y V            T T    +T   +  L+    Y   V+A+N  G   P      
Sbjct: 13322 INYVVQKRDAERKS-WSTVTTECSKTSFRVANLEEGKSYFFRVFAENEYGIGDPGETRDA 13380

Query: 1630  TNIDRPKG----LAFTDVDVDSIKIAWESPQG----QVSRYRVTYSSPEDGIHELFPAPD 1681
                 +  G    L    V   S  I W+ P      ++  Y V + + E+    +  +  
Sbjct: 13381 VKASQTPGPVVDLKVRSVSKSSCSIGWKKPHSDGGSRIIGYVVDFLTEENKWQRVMKSLS 13440

Query: 1682  GEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQ 1741
              +    +L     G EYT  V A +++ E  P        + A  D     V    L  +
Sbjct: 13441 LQYSAKDLT---EGKEYTFRVSAENENGEGTP----SEITVVARDD-----VVAPDLDLK 13488

Query: 1742  WTPPNVQL----TGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKD 1797
               P    L    + +R+++  K K  P        D        L   T+  V   A+  
Sbjct: 13489 GLPDLCYLAKENSNFRLKIPIKGKPAPSVSWKKGEDP-------LATDTRVSVESSAVNT 13541

Query: 1798  TLTSRPAQ----GVVT-TLENVSPPRRARVT-----------------DATETTITISWR 1835
             TL     Q    G  T TL+NV+  +   ++                 + T   +T+ W 
Sbjct: 13542 TLIVYDCQKSDAGKYTITLKNVAGTKEGTISIKVVGKPGIPTGPIKFDEVTAEAMTLKWA 13601

Query: 1836  TKTET----ITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYL-----YTL 1886
                +     IT + ++   +     +         ++ +T L  G +Y   +     Y +
Sbjct: 13602 PPKDDGGSEITNYILEKRDSVNNKWVTCASAVQKTTFRVTRLHEGMEYTFRVSAENKYGV 13661

Query: 1887  NDNARSSPVVIDASTAI-DAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPG 1941
              +  +S P+V      + DAP     +    +S+ ++W  P+    + ITGY +++++  
Sbjct: 13662 GEGLKSEPIVARHPFDVPDAPPPPNIVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKERN 13721

Query: 1942  SPPREVVPRPRPGVTEATITGLEPGTEYTIYVIAL------KNNQKSEPLI--------G 1987
             S   +   +    + +  +TGL  G EY   V+A+      K +  SEP++        G
Sbjct: 13722 SLLWKRANKTPIRMRDFKVTGLTEGLEYEFRVMAINLAGVGKPSLPSEPVVALDPIDPPG 13781

Query: 1988  RKKTV-----QKTPFVTHPGYDTGN 2007
             + + +       T   T P YD G+
Sbjct: 13782 KPEVINITRNSVTLIWTEPKYDGGH 13806



 Score = 91.7 bits (226), Expect = 8e-18
 Identities = 294/1501 (19%), Positives = 530/1501 (35%), Gaps = 198/1501 (13%)

Query: 628   IQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISI 684
             + W  P     S I+ Y+L  R   +V   K    P    +    GL+ G  YE ++ +I
Sbjct: 13009 VSWKPPADDGGSPITGYLLEKRETQAVNWTKVNRKPIIERTLKATGLQEGTEYEFRVTAI 13068

Query: 685   QQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSW---- 740
              + G  + +              S         + P       V + T SS  +SW    
Sbjct: 13069 NKAGPGKPSD------------ASKAAYARDPQYPPGPPAFPKVYDTTRSSVSLSWGKPA 13116

Query: 741   VSASDTVSGFRVEYELSEEGDEPQYLDLPST--ATSVNIPDLLPGRKYIVNVYQISEDGE 798
                   + G+ VE + + + D     +LP     T   +  L+   +Y   VY +++ G 
Sbjct: 13117 YDGGSPIIGYLVEVKRA-DSDNWVRCNLPQNLQKTRFEVTGLMEDTQYQFRVYAVNKIG- 13174

Query: 799   QSLILSTSQTTAPD--------APPDPTVDQVDDTSIVVR---WSRPQAPITGYRIVYSP 847
                   +  +  PD         PP+  +D     ++++R     R   P+ G      P
Sbjct: 13175 -----YSDPSDVPDKHYPKDILIPPEGELDADLRKTLILRAGVTMRLYVPVKGRP---PP 13226

Query: 848   SVEGSSTELNLPETAN-SVTLSDLQPGV-----------QYNITIYAVEENQESTPVVIQ 895
              +  S   +NL +     +  +D    +           +Y +T+      +E T VV  
Sbjct: 13227 KITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKYILTLENSCGKKEYTIVVKV 13286

Query: 896   QETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPGEHG 951
              +T G P + TV         E++     + W PP     S +  Y V            
Sbjct: 13287 LDTPGPPVNVTVK--------EISKDSAYVTWEPPIIDGGSPIINYVVQKRDAERKSWST 13338

Query: 952   QRLPISRNTFAEVTGLSPGVTYYFKVFAVSH---GRESKPLTAQQTTKLDAP-TNLQFVN 1007
                  S+ +F  V  L  G +Y+F+VFA +    G   +   A + ++   P  +L+  +
Sbjct: 13339 VTTECSKTSF-RVANLEEGKSYFFRVFAENEYGIGDPGETRDAVKASQTPGPVVDLKVRS 13397

Query: 1008  ETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYT 1063
              + S+  + W  P     ++I GY +   LT   + ++     S+ +Y  ++L    EYT
Sbjct: 13398 VSKSSCSIGWKKPHSDGGSRIIGYVVDF-LTEENKWQRVMKSLSL-QYSAKDLTEGKEYT 13455

Query: 1064  VSLVAIKGNQE-SPKATGVFT---TLQPG---SSIPPYNTEVTETT-----IVITWTPAP 1111
               + A   N E +P    V      + P      +P       E +     I I   PAP
Sbjct: 13456 FRVSAENENGEGTPSEITVVARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPIKGKPAP 13515

Query: 1112  RIGFKLGVRP-SQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKV 1170
              + +K G  P +       E ++ + +++V          YTI +      ++  I  KV
Sbjct: 13516 SVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKEGTISIKV 13575

Query: 1171  VTPLSPPTNLHLEANPDTGVLTVSW---ERSTTPDITGYRITTTPTNGQQGNSLEEVVHA 1227
             V     PT            +T+ W   +     +IT Y +    +   +  +    V  
Sbjct: 13576 VGKPGIPTGPIKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDSVNNKWVTCASAV-- 13633

Query: 1228  DQSSCTFDNLSPGLEYNVSV-----YTVKDDKESVPI---SDTIIPAVPPPTDLRFTNIG 1279
              +++     L  G+EY   V     Y V +  +S PI       +P  PPP ++   ++ 
Sbjct: 13634 QKTTFRVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVPDAPPPPNI--VDVR 13691

Query: 1280  PDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVA-----ELSISPSDNAVVLTNLLPGTEY 1334
              D++ +TW  P     +     +   K    +      +  I   D  V  T L  G EY
Sbjct: 13692 HDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTPIRMRDFKV--TGLTEGLEY 13749

Query: 1335  VVSVSSVYEQHESTPLRGRQKT----GLDSPTGIDFSDITANSFTVHWIAPR----ATIT 1386
                V ++       P    +       +D P   +  +IT NS T+ W  P+      +T
Sbjct: 13750 EFRVMAINLAGVGKPSLPSEPVVALDPIDPPGKPEVINITRNSVTLIWTEPKYDGGHKLT 13809

Query: 1387  GYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN--GREESPLLIGQQ 1444
             GY +           + + V     + T+T+L  G +Y   I A N  G   +P     +
Sbjct: 13810 GYIVEKRDLPSKSWMKANHVNVPECAFTVTDLVEGGKYEFRIRAKNTAGAISAP----SE 13865

Query: 1445  STVSDVPRDLEVVAATPTSLLISWDAPAVTVR----------------YYRITYGETGGN 1488
             ST + + +D       PT +L       +T++                  + ++ + G +
Sbjct: 13866 STETIICKD---EYEAPTIVLDPTIKDGLTIKAGDTIVLNAISILGKPLPKSSWSKAGKD 13922

Query: 1489  SPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQM 1548
                 + T   S  T+++  +K         Y +T         + + +        P  +
Sbjct: 13923 IRPSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFGTKVEHVKVTVLDVPGPPGPV 13982

Query: 1549  QVTDVQDNSISVKWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQP 1604
             ++++V     ++ W P      SP+  Y +     +    T           +  + +Q 
Sbjct: 13983 EISNVSAEKATLTWTPPLEDGGSPIKSYILEKRETSRLLWTVVSEDIQSCRHVATKLIQG 14042

Query: 1605  TVEYVVSVYAQNPSGESQPLVQTAVTNIDR------PKGLAFTDVDVDSIKIAWESP--- 1655
               EY+  V A N  G+ +P+    V  +DR      P+    ++V  ++  ++W+ P   
Sbjct: 14043 N-EYIFRVSAVNHYGKGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSWKRPVDD 14101

Query: 1656  -QGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVA-----LHDDM 1709
                +++ Y V     +             +   ++ GL+ GS Y   V A     +    
Sbjct: 14102 GGSEITGYHVERREKKSLRWVRAIKTPVSDLRCKVTGLQEGSTYEFRVSAENRAGIGPPS 14161

Query: 1710  ESQPLIGTQSTAIP--APTDLKFTQVTPTSLSAQWTPPN----VQLTGYRVRVTPKEKTG 1763
             E+   +  +  A P   P++   T  T  S S  W  P+    +++TGY   V   +K G
Sbjct: 14162 EASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLAWGKPHYDGGLEITGY---VVEHQKVG 14218

Query: 1764  PMKEI----NLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRR 1819
                 I      A   +  VV  L    KY   + A+ D     PA  V+  +E V     
Sbjct: 14219 DEAWIKDTTGTALRITQFVVPDLQTKEKYNFRISAINDAGVGEPA--VIPDVEIVEREMA 14276

Query: 1820  ARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIK-------PDVRSYTITG 1872
                    E   T+  R          +   PA   T  +  I         +  S+T+  
Sbjct: 14277 PDFELDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKNRANIENTESFTLLI 14336

Query: 1873  LQPGTDYKI--YLYTLNDNARSSPVVIDASTAIDAPS---NLRFLATTPNSLLVSWQPP- 1926
             +     Y    ++ T+ + A      ++    +D P    NLR    T +S+ + W  P 
Sbjct: 14337 IPECNRYDTGKFVMTIENPAGKKSGFVNV-RVLDTPGPVLNLRPTDITKDSVTLHWDLPL 14395

Query: 1927  ---RARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSE 1983
                 +RIT YI++ ++  +         +       +TGL  G EY   V+A       E
Sbjct: 14396 IDGGSRITNYIVE-KREATRKSYSTATTKCHKCTYKVTGLSEGCEYFFRVMAENEYGIGE 14454

Query: 1984  P 1984
             P
Sbjct: 14455 P 14455



 Score = 90.9 bits (224), Expect = 1e-17
 Identities = 273/1318 (20%), Positives = 459/1318 (34%), Gaps = 189/1318 (14%)

Query: 771   TATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPP---DPTVDQVDDTSI 827
             ++TS  + DL     +   V   +E G      +T    A + P    D ++     TS+
Sbjct: 20923 SSTSFKLIDLSEKTPFFFRVLAENEIGIGEPCETTEPVKAAEVPAPIRDLSMKDSTKTSV 20982

Query: 828   VVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAV 883
             ++ W++P     + IT Y +      E + +   + +T   + +S L+        ++A 
Sbjct: 20983 ILSWTKPDFDGGSVITEYVVERKGKGEQTWSHAGISKTCE-IEVSQLKEQSVLEFRVFAK 21041

Query: 884   EENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIP 943
              E   S PV I   T      + + +P ++   ++   +VT+           Y+    P
Sbjct: 21042 NEKGLSDPVTIGPITV----KELIITP-EVDLSDIPGAQVTVRIGHNVHLELPYKGKPKP 21096

Query: 944   VNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTN- 1002
                  + G  LP+  + F   +     +T   K     HG +   +      ++  P   
Sbjct: 21097 SISWLKDG--LPLKESEFVRFSKTENKITLSIKNAKKEHGGKYTVILDNAVCRIAVPITV 21154

Query: 1003  ------------LQFVNETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGP 1046
                         ++F      +V++ W  P      +IT Y +    T +   +      
Sbjct: 21155 ITLGPPSKPKGPIRFDEIKADSVILSWDVPEDNGGGEITCYSIEKRETSQTNWKMVCSSV 21214

Query: 1047  SVSKYPLRNLQPASEYTVSLVAI-KGNQESPKATGVFTTLQ----PGSSIPPYNTEVTET 1101
             + + + + NL   +EY   + A  +     P  + +         PG    P    VT  
Sbjct: 21215 ARTTFKVPNLVKDAEYQFRVRAENRYGVSQPLVSSIIVAKHQFRIPGPPGKPVIYNVTSD 21274

Query: 1102  TIVITWTP------APRIGFKLGVRPSQGGEAPREVTSD-SG-SIVVSGLTPGVEYVYTI 1153
              + +TW        +   GF +  +        +  TS  SG     +GL  G++Y + +
Sbjct: 21275 GMSLTWDAPVYDGGSEVTGFHVEKKERNSILWQKVNTSPISGREYRATGLVEGLDYQFRV 21334

Query: 1154  QVLRDG---QERDAPIVNKVVTPLSPP-TNLHLEANPDTGVLTVSWE---RSTTPDITGY 1206
                         D       V+P+ PP T  +++   +T  +T+ W    R     I GY
Sbjct: 21335 YAENSAGLSSPSDPSKFTLAVSPVDPPGTPDYIDVTRET--ITLKWNPPLRDGGSKIVGY 21392

Query: 1207  RITTTPTNGQQGNSL-EEVVHADQSSC--TFDNLSPGLEYNV------SVYTVKDDKESV 1257
              I       +QGN         D S C  T   LSPG  Y        +V T+    +S 
Sbjct: 21393 SIEK-----RQGNERWVRCNFTDVSECQYTVTGLSPGDRYEFRIIARNAVGTISPPSQSS 21447

Query: 1258  PISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNE---EDVAEL 1314
              I  T    VPP         GP+                 LV+  PV      +D  E+
Sbjct: 21448 GIIMTRDENVPP-----IVEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVTWFKDGVEI 21502

Query: 1315  SISPSDNAVVLTNLLPGTEYVV--------SVSSVYEQHESTPLRGRQKTGLDSPTG--- 1363
                 +   + +T++L  T   V         V +V  ++ S   +   K  +    G   
Sbjct: 21503 EKRMN---MEITDVLGSTSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQDTPGKVV 21559

Query: 1364  --IDFSDITANSFTVHWIAPR----ATITGYRI-RHHPEHFSGRPREDRVPHSRNSITLT 1416
               I F++IT    T+ W AP     A IT Y I +      +    ED+      S T  
Sbjct: 21560 GPIRFTNITGEKMTLWWDAPLNDGCAPITHYIIEKRETSRLAWALIEDKC--EAQSYTAI 21617

Query: 1417  NLTPGTEYVVSIVALN----GR--EESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDA 1470
              L  G EY   + A+N    GR  +  P++   Q TV D P   E    T  S+ ++W  
Sbjct: 21618 KLINGNEYQFRVSAVNKFGVGRPLDSDPVVAQIQYTVPDAPGIPEPSNITGNSITLTWAR 21677

Query: 1471  PAVTVRYYRITYGETGGNSPVQEFTV-----------------PGSKSTATISGLKPGVD 1513
             P            E+ G S +Q++ +                 P S++   ++GL  G +
Sbjct: 21678 P------------ESDGGSEIQQYILERREKKSTRWVKVISKRPISETRFKVTGLTEGNE 21725

Query: 1514  YTITVYAVTGRGDSPASSKPISINYRTEIDKPSQ---MQVTDVQDNSISVKW----LPSS 1566
             Y   V A    G  PAS     I  R  ++ P     ++VTD    ++S++W        
Sbjct: 21726 YEFHVMAENAAGVGPASGISRLIKCREPVNPPGPPTVVKVTDTSKTTVSLEWSKPVFDGG 21785

Query: 1567  SPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQ 1626
               + GY +     +     K       +T  T+  LQ   EY   V A N +G+      
Sbjct: 21786 MEIIGYIIEMCKADLGDWHKVNAEACVKTRYTVTDLQAGEEYKFRVSAINGAGKGDSCEV 21845

Query: 1627  TA-VTNIDRPKGLAFTDVDVDS-IKIAWESPQGQVSRYRVTY----------SSPEDGIH 1674
             T  +  +DR   L   ++D+D+  K       G   R  + Y          S P+  + 
Sbjct: 21846 TGTIKAVDR---LTAPELDIDANFKQTHVVRAGASIRLFIAYQGRPTPTAVWSKPDSNLS 21902

Query: 1675  ---ELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFT 1731
                ++         T E        +YT++V            +    T  P P  + F 
Sbjct: 21903 LRADIHTTDSFSTLTVENCNRNDAGKYTLTVENNSGSKSITFTVKVLDTPGP-PGPITFK 21961

Query: 1732  QVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKE----INLAPDSSSVVVSGLMVATK 1787
              VT  S +  W  P +   G R+     EK    +     I+         V+ L     
Sbjct: 21962 DVTRGSATLMWDAPLLD-GGARIHHYVVEKREASRRSWQVISEKCTRQIFKVNDLAEGVP 22020

Query: 1788  YEVSVYALKDTLTSRPAQ--GVVTTLENVSPPRRARVTDATETTITISW----RTKTETI 1841
             Y   V A+ +     P +    +   E  +PPRR  V D ++++  ++W          I
Sbjct: 22021 YYFRVSAVNEYGVGEPYEMPEPIVATEQPAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRI 22080

Query: 1842  TGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDAST 1901
             TG+ ++         ++      + ++T+  L   T+Y+  +   ND   S P    +S 
Sbjct: 22081 TGYLLEMRQKGSDFWVEAGHTKQL-TFTVERLVEKTEYEFRVKAKNDAGYSEPREAFSSV 22139

Query: 1902  AIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVP---RPRPGVT 1956
              I  P         P + L         IT  +I   K GSP    VP   RP P VT
Sbjct: 22140 IIKEPQ------IEPTADLTG-------ITNQLITC-KAGSPFTIDVPISGRPAPKVT 22183



 Score = 89.7 bits (221), Expect = 3e-17
 Identities = 260/1286 (20%), Positives = 475/1286 (36%), Gaps = 231/1286 (17%)

Query: 780  LLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPIT 839
            ++P ++Y++ V  ++  G       +    A D    PT+D      IV+   +   P+ 
Sbjct: 7853 VVPDKEYVLRVRAVNAIGVSEPSEISENVVAKDPDCKPTIDLETHDIIVIEGEKLSIPVP 7912

Query: 840  GYRIVYSPSV----EGSSTELNLPETANSVTLS---DLQPGVQYNITIYAV--EENQEST 890
             +R V  P+V    +G   + +   T  +  +S   ++   V+ +  IY +  E    S 
Sbjct: 7913 -FRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSA 7971

Query: 891  PVVIQQETTGTPRSDTVPSP-RDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGE 949
               I  +  G      +P P +D++  ++T     + W PPE    G    +  V    E
Sbjct: 7972 TASINVKVIG------LPGPCKDIKASDITKSSCKLTWEPPE--FDGGTPILHYVLERRE 8023

Query: 950  HGQR--LPI--SRNTFA-EVTGLSPGVTYYFKVFAVSH--GRE----SKPLTAQQTTKL- 997
             G+R  +P+    N  +  V  L P   Y+F+V AV+   G E      P+ AQ   +  
Sbjct: 8024 AGRRTYIPVMSGENKLSWTVKDLIPNGEYFFRVKAVNKVGGGEYIELKNPVIAQDPKQPP 8083

Query: 998  DAPTNLQFVNETDSTVLVRWTPPR----AQITGY---RLTVGLTRRGQPRQYNVGPSVSK 1050
            D P +++  N T   + + W PP     ++I GY   ++  G  R  +  ++ V   +  
Sbjct: 8084 DPPVDVEVHNPTAEAMTITWKPPLYDGGSKIMGYIIEKIAKGEERWKRCNEHLV--PILT 8141

Query: 1051 YPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPA 1110
            Y  + L+   EY   + A         A G+    +P  + PP        T  +    A
Sbjct: 8142 YTAKGLEEGKEYQFRVRA-------ENAAGIS---EPSRATPP--------TKAVDPIDA 8183

Query: 1111 PRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVL--RDGQERDAPIVN 1168
            P++  +  +   +G E   +  S SGS       P + ++    V+   + ++R AP+V 
Sbjct: 8184 PKVILRTSLEVKRGDEIALDA-SISGSPY-----PTITWIKDENVIVPEEIKKRAAPLVR 8237

Query: 1169 KVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHAD 1228
            +    +       L   P T  L++                    N ++G S   V    
Sbjct: 8238 RRKGEVQEEEPFVL---PLTQRLSID-------------------NSKKGESQLRVR--- 8272

Query: 1229 QSSCTFDNLSPGLEYNVSVYTVKDDK--ESVPISDTIIPAVPPPTDLRFTNIGPDTMRVT 1286
                  D+L P  ++ + +  V++D      P + +++    PP +  F +I   ++   
Sbjct: 8273 ------DSLRP--DHGLYMIKVENDHGIAKAPCTVSVLDTPGPPINFVFEDIRKTSVLCK 8324

Query: 1287 WAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHE 1346
            W PP   D  + ++ Y+  K ++        P    +V+T+ L   +Y  SV+ + E  E
Sbjct: 8325 WEPPLD-DGGSEIINYTLEKKDKT------KPDSEWIVVTSTLRHCKY--SVTKLIEGKE 8375

Query: 1347 ------------------STPLRGRQKTGL-DSPTGIDFSDITANSFTVHWIAPR---AT 1384
                              S PL  +   G  D+P      D+T+NS  V W  P+   + 
Sbjct: 8376 YLFRVRAENRFGPGPPCVSKPLVAKDPFGPPDAPDKPIVEDVTSNSMLVKWNEPKDNGSP 8435

Query: 1385 ITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN----GREESPLL 1440
            I GY +     + +   R ++   +     +  L  G  YV  + A N    G+   P  
Sbjct: 8436 ILGYWLEKREVNSTHWSRVNKSLLNALKANVDGLLEGLTYVFRVCAENAAGPGKFSPP-- 8493

Query: 1441 IGQQSTVSD--------VPRDLEVVAATPTSLLISWDAPAVT----VRYYRITYGETGGN 1488
                 T  D        +PR   V   + T++ + W+ PA      +  Y +     G N
Sbjct: 8494 -SDPKTAHDPISPPGPPIPR---VTDTSSTTIELEWEPPAFNGGGEIVGYFVDKQLVGTN 8549

Query: 1489 SPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDS-PASSKPISINYRTEIDKPSQ 1547
               +           T+  ++ G DY + V AV   G+  P  ++P+++    E  +P  
Sbjct: 8550 EWSRCTEKMIKVRQYTVKEIREGADYKLRVSAVNAAGEGPPGETQPVTV---AEPQEPPA 8606

Query: 1548 MQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTK--TKTAGP-DQTEMTIEGLQP 1604
            +++       +SVK           R+       P PTK  TK  G  D+  + I+ +  
Sbjct: 8607 VEL------DVSVKGGIQIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKDRVVIDNVGT 8660

Query: 1605 TVEYVVS-----------VYAQNPSGESQPLVQTAVTNIDRP-KGLAFTDVDVDSIKIAW 1652
              E ++            + A N  G      +  V ++  P   L     +     + W
Sbjct: 8661 KSELIIKDALRKDHGRYVITATNSCGSKFAAARVEVFDVPGPVLDLKPVVTNRKMCLLNW 8720

Query: 1653 ESPQ----GQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALH-- 1706
              P+     +++ + +     +  +H      + E    ++ GL  G EY   V+A +  
Sbjct: 8721 SDPEDDGGSEITGFIIERKDAK--MHTWRQPIETERSKCDITGLLEGQEYKFRVIAKNKF 8778

Query: 1707 ---DDMESQPLIGTQSTAIP-APTDLKFTQVTPTSLSAQWTPPNVQ----LTGYRVRVTP 1758
                 +E  P++       P +P  L +T+ T ++++  W  P       + GY +    
Sbjct: 8779 GCGPPVEIGPILAVDPLGPPTSPERLTYTERTKSTITLDWKEPRSNGGSPIQGYIIEKRR 8838

Query: 1759 KEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPA--QGVVTTLENVSP 1816
             +K    +       ++S +V  L     YE  V A+ +   S P+    VV   + V P
Sbjct: 8839 HDKPDFERVNKRLCPTTSFLVENLDEHQMYEFRVKAVNEIGESEPSLPLNVVIQDDEVPP 8898

Query: 1817 PRRARVTDATETTIT-------------------ISWRTKTETITGFQVDAVPANGQTPI 1857
              + R++   +T                      I W +K ET+     DA+    +   
Sbjct: 8899 TIKLRLSVRGDTIKVKAGEPVHIPADVTGLPMPKIEW-SKNETVIEKPTDALQITKEEVS 8957

Query: 1858 QRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAI-DAPSNLRFLATT- 1915
            +   K ++          GT      YT+  + R   V  +    + D PS  R LA T 
Sbjct: 8958 RSEAKTELSIPKAVREDKGT------YTVTASNRLGSVFRNVHVEVYDRPSPPRNLAVTD 9011

Query: 1916 --PNSLLVSWQPP----RARITGYII 1935
                S  ++W  P     + IT Y+I
Sbjct: 9012 IKAESCYLTWDAPLDNGGSEITHYVI 9037



 Score = 89.7 bits (221), Expect = 3e-17
 Identities = 320/1572 (20%), Positives = 568/1572 (36%), Gaps = 254/1572 (16%)

Query: 611   PVEVFITETPSQP----------NSHPIQWNAPQP---SHISKYILRWRPKNSVGRWKEA 657
             P  +  TE P+ P          +S  + W  P     S I+ Y+L  R K S   W EA
Sbjct: 22040 PEPIVATEQPAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGS-DFWVEA 22098

Query: 658   TIPGHLN--SYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNT--VTG 713
                GH    ++T++ L     YE ++ +    G+ E  R  F++     P    T  +TG
Sbjct: 22099 ---GHTKQLTFTVERLVEKTEYEFRVKAKNDAGYSE-PREAFSSVIIKEPQIEPTADLTG 22154

Query: 714   ETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTAT 773
              T       A S    ++  S      V+       +++E    +E D    +      T
Sbjct: 22155 ITNQLITCKAGSPFTIDVPISGRPAPKVT-------WKLEEMRLKETDRVS-ITTTKDRT 22206

Query: 774   SVNIPDLLPGR--KYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPT-VDQVDDTSIVVR 830
             ++ + D + G   +Y + +   +  G ++  ++      P     P  V  V   S V+ 
Sbjct: 22207 TLTVKDSMRGDSGRYFLTLENTA--GVKTFSVTVVVIGRPGPVTGPIEVSSVSAESCVLS 22264

Query: 831   WSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITI-----Y 881
             W  P+      IT Y +    S   +   +N       + ++ L   ++Y+  +     +
Sbjct: 22265 WGEPKDGGGTEITNYIVEKRESGTTAWQLVNSSVKRTQIKVTHLTKYMEYSFRVSSENRF 22324

Query: 882   AVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGY 937
              V +  ES P++ +      P + T P     +   V+   ++I W  P     S + GY
Sbjct: 22325 GVSKPLESAPIIAEHPFV-PPSAPTRP-----EVYHVSANAMSIRWEEPYHDGGSKIIGY 22378

Query: 938   RVDVIPVN-LPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFA-----VSHGRE-SKPLT 990
              V+    N +      ++P     + +VTGL  G+ Y F+ +A     VS   E S+P+ 
Sbjct: 22379 WVEKKERNTILWVKENKVPCLECNY-KVTGLVEGLEYQFRTYALNAAGVSKASEASRPIM 22437

Query: 991   AQQTTKLDAPTNLQFVNETDSTVLVRWTPPR----AQITGYRL----------------- 1029
             AQ    +DAP   +  + T STV + W+ P     +++ GY +                 
Sbjct: 22438 AQ--NPVDAPGRPEVTDVTRSTVSLIWSAPAYDGGSKVVGYIIERKPVSEVGDGRWLKCN 22495

Query: 1030  ---------TVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKAT- 1079
                      TV     G   ++ V   ++K     +   SE T   V  +     PKA  
Sbjct: 22496 YTIVSDNFFTVTALSEGDTYEFRV---LAKNAAGVISKGSEST-GPVTCRDEYAPPKAEL 22551

Query: 1080  -----GVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGE-APREVTS 1133
                  G   T++ GS +             +   P P+I +  G +     E    + T 
Sbjct: 22552 DARLHGDLVTIRAGSDL--------VLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTG 22603

Query: 1134  DSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTV 1193
                + V+          YT+ V      +   ++ KV+    P   L + +       T+
Sbjct: 22604 KRATAVIKFCDRSDSGKYTLTVKNASGTKAVSVMVKVLDSPGPCGKLTV-SRVTQEKCTL 22662

Query: 1194  SWERSTTPDITGYRITTTPTNGQQGNSLEEVV---HADQSSCTFDNLSPGLEYNVSVYTV 1250
             +W  S   +  G  IT      ++ + L  V+        S     L    EY   V  V
Sbjct: 22663 AW--SLPQEDGGAEITHYIVERRETSRLNWVIVEGECPTLSYVVTRLIKNNEYIFRVRAV 22720

Query: 1251  KDDKESVPISDTIIPA-----VP-PPTDLRFTNIGPDTMRVTWAPPPS---IDLTNFLV- 1300
                   VP+    I A     +P PP        G + + + W  P S    +++N+LV 
Sbjct: 22721 NKYGPGVPVESEPIVARNSFTIPSPPGIPEEVGTGKEHIIIQWTKPESDGGNEISNYLVD 22780

Query: 1301  -------RYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGR 1353
                    R++ V  +  V        D  + +T+L+ G +Y   V++V     S P    
Sbjct: 22781 KREKKSLRWTRVNKDYVV-------YDTRLKVTSLMEGCDYQFRVTAVNAAGNSEPSEAS 22833

Query: 1354  QKTGL-------DSPTGIDFSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPR 1402
                           P+     D T +S ++ W  P       I GY +    +      R
Sbjct: 22834 NFISCREPSYTPGPPSAPRVVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDTDQWYR 22893

Query: 1403  EDRVPHSRNS-ITLTNLTPGTEYVVSIVALN--GREESPLLIGQQSTVS--DVPRDLEVV 1457
                    RN+  T+ +L  G +Y   + A+N  G  E    I +   V   ++P DLE+ 
Sbjct: 22894 VHTNATIRNTEFTVPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEIP-DLELA 22952

Query: 1458  AATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTIT 1517
                  ++ I   A        R+    +G   PV  ++  G    A+ + +     Y++ 
Sbjct: 22953 DDLKKTVTIRAGAS------LRLMVSVSGRPPPVITWSKQGI-DLASRAIIDTTESYSLL 23005

Query: 1518  V-----------YAVTGRGDSPASSKPISIN-YRTEIDKPSQMQVTDVQDNSISVKW--- 1562
             +           Y +     S   S  + +  Y T    PS ++V +V  +S+++ W   
Sbjct: 23006 IVDKVNRYDAGKYTIEAENQSGKKSATVLVKVYDTPGPCPS-VKVKEVSRDSVTITWEIP 23064

Query: 1563  -LPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGES 1621
              +   +PV  Y +    +      KT T    +T   I GL     Y   V  +N  G  
Sbjct: 23065 TIDGGAPVNNY-IVEKREAAMRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYGIG 23123

Query: 1622  QPLVQTAVTNIDR----PKGLAFTDVDVDSIKIAWESP----QGQVSRY--RVTYSSPED 1671
             +P   +    +      P  L   DV   ++ +AWE P      +++ Y      +  E 
Sbjct: 23124 EPCETSDAVLVSEVPLVPAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGTER 23183

Query: 1672  GIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFT 1731
              +  +   P   E T  +  L  G +Y   + A ++   S+P    ++       DL+  
Sbjct: 23184 WMKVVTLKPTVLEHT--VTSLNEGEQYLFRIRAQNEKGVSEP---RETVTAVTVQDLR-- 23236

Query: 1732  QVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSG--------LM 1783
              V PT   +      + +   R    P E   P+      P ++S   +G        + 
Sbjct: 23237 -VLPTIDLSTMPQKTIHVPAGR----PVELVIPI--AGRPPPAASWFFAGSKLRESERVT 23289

Query: 1784  VATKYEVSVYALKDTLTSRPAQGVVTTLENVS-----------------PPRRARVTDAT 1826
             V T  +V+   +++T T R        L+NV+                 P    ++ +  
Sbjct: 23290 VETHTKVAKLTIRET-TIRDTGEYTLELKNVTGTTSETIKVIILDKPGPPTGPIKIDEID 23348

Query: 1827  ETTITISWRTKT----ETITGFQVDAVPAN--GQTPIQRTIKPDVRSYTITGLQPGTDYK 1880
              T+ITISW          ++G+ V+   A+  G  P+  ++     ++  T L  G +Y 
Sbjct: 23349 ATSITISWEPPELDGGAPLSGYVVEQRDAHRPGWLPVSESVTRS--TFKFTRLTEGNEYV 23406

Query: 1881  IYLYTLNDNARSSPV---VIDASTAI---DAPSNLRFLATTPNSLLVSWQPPR----ARI 1930
               +   N     S +   VI+  ++I     P  L+    + + + ++W PP     +++
Sbjct: 23407 FRVAATNRFGIGSYLQSEVIECRSSIRIPGPPETLQIFDVSRDGMTLTWYPPEDDGGSQV 23466

Query: 1931  TGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKK 1990
             TGYI++ ++  +     V +    +T    TGL  G EY   V A+      +P    K 
Sbjct: 23467 TGYIVERKEVRADRWVRVNKVPVTMTRYRSTGLTEGLEYEHRVTAINARGSGKPSRPSKP 23526

Query: 1991  TVQKTPFVTHPG 2002
              V   P +  PG
Sbjct: 23527 IVAMDP-IAPPG 23537



 Score = 88.2 bits (217), Expect = 9e-17
 Identities = 339/1547 (21%), Positives = 534/1547 (34%), Gaps = 251/1547 (16%)

Query: 628   IQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISI 684
             + W +P+    S I+ Y++  R  +    W   T      + T++GL  G  Y  ++ + 
Sbjct: 10138 LTWFSPEDDGGSPITNYVIEKRESDRRA-WTPVTYTVTRQNATVQGLIQGKAYFFRIAAE 10196

Query: 685   QQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSAS 744
                G        F  TS +  +        T P  P       V E+T ++  ++W    
Sbjct: 10197 NSIGMGP-----FVETSEALVIREPI----TVPERP---EDLEVKEVTKNTVTLTWNPPK 10244

Query: 745   DTVSGFRVEYELSEE--GDEPQYLDLPSTATS--VNIPDLLPGRKYIVNVYQISEDGEQS 800
                    + Y L     G E  +        S    +  L  G  Y   V  ++  G+  
Sbjct: 10245 YDGGSEIINYVLESRLIGTEKFHKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGK 10304

Query: 801   LILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPE 860
                 T   T  D    PT+       + +R     A    Y     P V     E ++ E
Sbjct: 10305 PSFCTKPITCKDELAPPTLHLDFRDKLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLE 10364

Query: 861   TANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQET---TGTPRSDTVPSPRD----L 913
               +  T     P       I A   +     VV++  T    G  + + V  P      +
Sbjct: 10365 --DDRTHIKTTPATLALEKIKAKRSDSGKYCVVVENSTGSRKGFCQVNVVDRPGPPVGPV 10422

Query: 914   QFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPGEHGQRLPI---SRNTFAEVTG 966
              F EVT   + I W PP     S +T Y ++   V         +P+   S  T  +V+ 
Sbjct: 10423 SFDEVTKDYMVISWKPPLDDGGSKITNYIIEKKEVG----KDVWMPVTSASAKTTCKVSK 10478

Query: 967   LSPGVTYYFKVFAVSHGRESKPLTAQQTTKLD------APTNLQFVNETDSTVLVRWTPP 1020
             L  G  Y F++ A +    S PL +      D      AP        T  + LV W  P
Sbjct: 10479 LLEGKDYIFRIHAENLYGISDPLVSDSMKAKDRFRVPDAPDQPIVTEVTKDSALVTWNKP 10538

Query: 1021  R---AQITGYRLTVGLTRRGQPRQYNVGP--SVSKYPLRNLQPASEYTVSLVA---IKGN 1072
                   IT Y L    T   +  +    P    +K+ + +L    +Y   + A   I   
Sbjct: 10539 HDGGKPITNYILEKRETMSKRWARVTKDPIHPYTKFRVPDLLEGCQYEFRVSAENEIGIG 10598

Query: 1073  QESPKATGVFTTLQPGSSIPPYNTEVTETT---IVITWTPAPR-------IGFKLGVRPS 1122
               SP +  VF         PP N E  +TT   + +TW P PR       +G+ +  +  
Sbjct: 10599 DPSPPSKPVFAKDPIAKPSPPVNPEAIDTTCNSVDLTWQP-PRHDGGSKILGYIVEYQ-K 10656

Query: 1123  QGGEAPREVTSDSGSIV-----VSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTP---L 1174
              G E  R       S       V+GL  G  Y + +  +    E D   V + V     L
Sbjct: 10657 VGDEEWRRANHTPESCPETKYKVTGLRDGQTYKFRVLAVNAAGESDPAHVPEPVLVKDRL 10716

Query: 1175  SPPTNLHLEANP---------DTGVLT----------VSWERSTTPDITGYRITTTPTNG 1215
              PP  L L+AN          DT  L+          V+W++      T  RI  TP   
Sbjct: 10717 EPP-ELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARIDVTPVGS 10775

Query: 1216  QQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRF 1275
             +    +    H D    +    +P     VSV  +  DK              PP DL  
Sbjct: 10776 KL--EIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDKPG------------PPRDLEV 10821

Query: 1276  TNIGPDTMRVTWAPPPSID---LTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGT 1332
             + I  D+  +TW  P       +TN++V    V + +  + LS +    +    +L  G 
Sbjct: 10822 SEIRKDSCYLTWKEPLDDGGSVITNYVVERRDVASAQ-WSPLSATSKKKSHFAKHLNEGN 10880

Query: 1333  EYVVSVSSVYEQHESTPLRGRQKT--GLDS------PTGIDFSDITANSFTVHWIAPR-- 1382
             +Y+  V++   Q+   P     K    LD       P  +   D+     ++ W  P   
Sbjct: 10881 QYLFRVAAE-NQYGRGPFVETPKPIKALDPLHPPGPPKDLHHVDVDKTEVSLVWNKPDRD 10939

Query: 1383  --ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN----GREE 1436
               + ITGY + +  E      +   V +      +T L  G  Y   + A N    G  +
Sbjct: 10940 GGSPITGYLVEYQEEGTQDWIKFKTVTNLE--CVVTGLQQGKTYRFRVKAENIVGLGLPD 10997

Query: 1437  SPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTV 1496
             + + I  Q  +  VP  +E+       L++       TVR+  I  G      P  ++T 
Sbjct: 10998 TTIPIECQEKL--VPPSVELDVKLIEGLVVK---AGTTVRFPAIIRGVP---VPTAKWTT 11049

Query: 1497  PGSK---------------STATISGL--KPGVDYTITVYAVTGRGDSPASSKPISINYR 1539
              GS+               S  TI     +   +Y ITV        + A SK ++++  
Sbjct: 11050 DGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEYQITV-------SNAAGSKTVAVHL- 11101

Query: 1540  TEIDKPSQ----MQVTDVQDNSISVKWLP----SSSPVTGYRVTT--TPKNGPGPTKTKT 1589
             T +D P      + + DV    +++ W P      SPV  Y V    T K+  G     +
Sbjct: 11102 TVLDVPGPPTGPINILDVTPEHMTISWQPPKDDGGSPVINYIVEKQDTRKDTWGVV---S 11158

Query: 1590  AGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDR------PKGLAFTDV 1643
             +G  +T++ I  LQ   EYV  V A+N  G   PL  T      +      P     TD+
Sbjct: 11159 SGSSKTKLKIPHLQKGCEYVFRVRAENKIGVGPPLDSTPTVAKHKFSPPSPPGKPVVTDI 11218

Query: 1644  DVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQ----GLRPGSEYT 1699
               ++  ++W  P+         Y      +   +   + +   A+L+    GL  G+ Y 
Sbjct: 11219 TENAATVSWTLPKSDGGSPITGYYMERREVTGKWVRVN-KTPIADLKFRVTGLYEGNTYE 11277

Query: 1700  VSVVALH------DDMESQPLIGTQSTAIPA-PTDLKFTQVTPTSLSAQWTPP----NVQ 1748
               V A +          S P+   +    P  P + K    +  +    WT P       
Sbjct: 11278 FRVFAENLAGLSKPSPSSDPIKACRPIKPPGPPINPKLKDKSRETADLVWTKPLSDGGSP 11337

Query: 1749  LTGYRVRVTPKEKTGPMKEINLAP--DSSSVVVSGLMVATKYEVSVYALKDTLTSRP--- 1803
             + GY V    K  T     IN        +  V GL+   +Y   + A        P   
Sbjct: 11338 ILGYVVE-CQKPGTAQWNRINKDELIRQCAFRVPGLIEGNEYRFRIKAANIVGEGEPREL 11396

Query: 1804  AQGVVTTLENVSPPR-------RARVTDATETTITISWRTK-------TETITG------ 1843
             A+ V+   + + PP        R  +T     TI I  R K       T T  G      
Sbjct: 11397 AESVIAK-DILHPPEVELDVTCRDVITVRVGQTIRILARVKGRPEPDITWTKEGKVLVRE 11455

Query: 1844  FQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAI 1903
              +VD +    +  +Q  IK  VR+           Y I     + +A+ S +V      +
Sbjct: 11456 KRVDLIQDLPRVELQ--IKEAVRA-------DHGKYIISAKNSSGHAQGSAIV----NVL 11502

Query: 1904  DAP---SNLRFLATTPNSLLVSWQPP----RARITGYIIKYEKPGSPPREVVPRPRPGVT 1956
             D P    NL+    T  +  +SW+ P     + IT +I++Y KP      +V      VT
Sbjct: 11503 DRPGPCQNLKVTNVTKENCTISWENPLDNGGSEITNFIVEYRKPNQKGWSIV---ASDVT 11559

Query: 1957  EATI-TGLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQKTPFVTHPG 2002
             +  I   L    EY   V A +N     P I  K  +     +  PG
Sbjct: 11560 KRLIKANLLANNEYYFRVCA-ENKVGVGPTIETKTPILAINPIDRPG 11605



 Score = 88.2 bits (217), Expect = 9e-17
 Identities = 260/1214 (21%), Positives = 438/1214 (36%), Gaps = 158/1214 (13%)

Query: 908   PSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPIS------RNTF 961
             P    L   EVT  K  + W PP     G ++D   V        RL  +      + T 
Sbjct: 15060 PPEGPLAVTEVTSEKCVLSWFPPLDD-GGAKIDHYIVQ--KRETSRLAWTNVASEVQVTK 15116

Query: 962   AEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKL------DAPTNLQFVNETDSTVLV 1015
              +VT L  G  Y F+V AV+     +PL ++    +      D P N +    T  +++V
Sbjct: 15117 LKVTKLLKGNEYIFRVMAVNKYGVGEPLESEPVLAVNPYGPPDPPKNPEVTTITKDSMVV 15176

Query: 1016  RWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVS-----KYPLRNLQPASEYTVSLVAIK 1070
              W  P +      +   + RR +  Q  +  +       +Y +  L    EY   ++A  
Sbjct: 15177 CWGHPDSDGGSEIINYIVERRDKAGQRWIKCNKKTLTDLRYKVSGLTEGHEYEFRIMAEN 15236

Query: 1071  -GNQESPKATGVF-----TTLQPGSSIPPYNTEVTET---TIVITWTP------APRIGF 1115
                  +P  T  F     T  +PG   PP N  V +T   +I I W        +   G+
Sbjct: 15237 AAGISAPSPTSPFYKACDTVFKPG---PPGNPRVLDTSRSSISIAWNKPIYDGGSEITGY 15293

Query: 1116  KLGVRPSQGGEAPREVTSDSG----SIVVSGLTPGVEYVYTIQVLRD---GQERDAPIVN 1168
              + +   +  E  + VT  +G    S  ++GLT   EY   I  +     G+    P   
Sbjct: 15294 MVEIALPEEDEW-QIVTPPAGLKATSYTITGLTENQEYKIRIYAMNSEGLGEPALVPGTP 15352

Query: 1169  KVVTPLSPP-TNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHA 1227
             K    + PP   L  +      +      R   P I G            G SL++    
Sbjct: 15353 KAEDRMLPPEIELDADLRKVVTIRACCTLRLFVP-IKGRPAPEVKWARDHGESLDKASIE 15411

Query: 1228  DQSSCTFDNLSPGLEYNVSVY--TVKDD--KESVPISDTIIPAVPPPTDLRFTNIGPDTM 1283
               SS T   +     ++   Y  TV++    +S  ++  ++    PP DL+   +   ++
Sbjct: 15412 STSSYTLLIVGNVNRFDSGKYILTVENSSGSKSAFVNVRVLDTPGPPQDLKVKEVTKTSV 15471

Query: 1284  RVTWAPPPSIDLTNFLVRYSPVKNE---EDVAELSISPSDNAVVLTNLLPGTEYVVSVSS 1340
              +TW  PP +D  + +  Y   K E   +  + ++ +    +  +  L  G  Y   V +
Sbjct: 15472 TLTW-DPPLLDGGSKIKNYIVEKRESTRKAYSTVATNCHKTSWKVDQLQEGCSYYFRVLA 15530

Query: 1341  VYEQHESTPLRGRQKTGLDS----PTGIDFSDITANSFTVHWIAPR----ATITGYRIRH 1392
               E     P    +          P  I   D+T NS ++ W  P     + I GY +  
Sbjct: 15531 ENEYGIGLPAETAESVKASERPLPPGKITLMDVTRNSVSLSWEKPEHDGGSRILGYIVEM 15590

Query: 1393  HPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPR 1452
               +          V       T+T L  G EY   + A N   E  +   +Q +V  + +
Sbjct: 15591 QTKGSDKWATCATV--KVTEATITGLIQGEEYSFRVSAQN---EKGISDPRQLSVPVIAK 15645

Query: 1453  DLEVVAA------TPTSLL---ISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTA 1503
             DL +  A      T T L    +  D P +      +T+ +   N P+++ T   ++ST 
Sbjct: 15646 DLVIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHK--DNVPLKQTTRVNAESTE 15703

Query: 1504  --TISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKP----SQMQVTDVQDNS 1557
               ++  +K      +  Y V     +  + + +++     +DKP      +++ +V  +S
Sbjct: 15704 NNSLLTIKDACREDVGHYVVKLTNSAGEAIETLNV---IVLDKPGPPTGPVKMDEVTADS 15760

Query: 1558  ISVKWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEG--LQPTVEYVVS 1611
             I++ W P      S +  Y V    K     T  +         TI+   L+   EY   
Sbjct: 15761 ITLSWGPPKYDGGSSINNYIV---EKRDTSTTTWQIVSATVARTTIKACRLKTGCEYQFR 15817

Query: 1612  VYAQNPSGE-----SQPLVQTAVTNIDRPKGLAFTDVDV-DSIKIAWESPQGQVSRYRVT 1665
             + A+N  G+     S+P V      +  P G     +   DS+++ W  P        + 
Sbjct: 15818 IAAENRYGKSTYLNSEPTVAQYPFKVPGPPGTPVVTLSSRDSMEVQWNEPISDGGSRVIG 15877

Query: 1666  YSSPEDGIHELF-------PAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQ 1718
             Y       + +        P P  +  T    GL  G EY   V A +     +P   ++
Sbjct: 15878 YHLERKERNSILWVKLNKTPIPQTKFKTT---GLEEGVEYEFRVSAENIVGIGKPSKVSE 15934

Query: 1719  STAIPAPTD----LKFTQVTPTSLSAQWTPPNV----QLTGYRVRVTPKEKTGPMKEINL 1770
                   P D     +   VT  S++ QW  P      ++TGY V      +   MK    
Sbjct: 15935 CYVARDPCDPPGRPEAIIVTRNSVTLQWKKPTYDGGSKITGYIVEKKELPEGRWMKASFT 15994

Query: 1771  APDSSSVVVSGLMVATKYEVSVYALKDT-LTSRPAQ--GVVTTLENVSPPRRARVTDATE 1827
                 +   V+GL+   +YE  V A     + S P++  G +T  + V PPR +      +
Sbjct: 15995 NIIDTHFEVTGLVEDHRYEFRVIARNAAGVFSEPSESTGAITARDEVDPPRISMDPKYKD 16054

Query: 1828  TTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQ-PGTDYKIYLYTL 1886
             T +  +  +       F+VDA       P  + IK D        L+   TD+   L ++
Sbjct: 16055 TIVVHAGES-------FKVDADIYGKPIPTIQWIKGDQELSNTARLEIKSTDFATSL-SV 16106

Query: 1887  NDNAR--SSPVVIDASTAIDAPS---NLRFL-------------ATTPNSLLVSWQPP-- 1926
              D  R  S   ++ A       S   N++ L               T     ++W+PP  
Sbjct: 16107 KDAVRVDSGNYILKAKNVAGERSVTVNVKVLDRPGPPEGPVVISGVTAEKCTLAWKPPLQ 16166

Query: 1927  --RARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEP 1984
                + I  YI++  +       VV           +T L  G EYT  ++A+      EP
Sbjct: 16167 DGGSDIINYIVERRETSRLVWTVVD-ANVQTLSCKVTKLLEGNEYTFRIMAVNKYGVGEP 16225

Query: 1985  LIGRKKTVQKTPFV 1998
             L   +  V K PFV
Sbjct: 16226 L-ESEPVVAKNPFV 16238



 Score = 86.3 bits (212), Expect = 3e-16
 Identities = 274/1330 (20%), Positives = 481/1330 (36%), Gaps = 177/1330 (13%)

Query: 812   DAPPDPT----VDQVDDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETAN 863
             D P  PT    +  + + S+ ++W  P+    + +T Y ++   +     TE++      
Sbjct: 20071 DRPGPPTGPVVISDITEESVTLKWEPPKYDGGSQVTNYILLKRETSTAVWTEVSATVART 20130

Query: 864   SVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFV-EVTDVK 922
              + +  L  G +Y   I A  EN+      I           T P P    +V  VT   
Sbjct: 20131 MMKVMKLTTGEEYQFRIKA--ENRFGISDHIDSACVTVKLPYTTPGPPSTPWVTNVTRES 20188

Query: 923   VTIMWTPPES----AVTGYRVDVIPVN-LPGEHGQRLPISRNTFAEVTGLSPGVTYYFKV 977
             +T+ W  P S    AV GY +++   N +  +   +L I R T  +VT +S G+ Y F+V
Sbjct: 20189 ITVGWHEPVSNGGSAVVGYHLEMKDRNSILWQKANKLVI-RTTHFKVTTISAGLIYEFRV 20247

Query: 978   FAVSHGRESKPL-TAQQTTKLDA---PTNLQFVNETDSTVLVRWTPPR----AQITGYRL 1029
             +A +     KP   ++    +DA   P N++  + + ++V + W  P     ++ITGY  
Sbjct: 20248 YAENAAGVGKPSHPSEPVLAIDACEPPRNVRITDISKNSVSLSWQQPAFDGGSKITGYI- 20306

Query: 1030  TVGLTRRGQP-----RQYNVGPSVSKYPLRNLQPASEYTVSLVA--IKGNQESP-KATGV 1081
                + RR  P     +      + +++ +  L   S+Y   + A    G+  +P +  G 
Sbjct: 20307 ---VERRDLPDGRWTKASFTNVTETQFIISGLTQNSQYEFRVFARNAVGSISNPSEVVGP 20363

Query: 1082  FTTLQ----PGSSIPPYNTEVTE----TTIV----ITWTPAPRI-GFKLGVRPSQGGEAP 1128
              T +     P   +P   TEV +    T++     I+  PAP I  +K            
Sbjct: 20364 ITCIDSYGGPVIDLPLEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVC 20423

Query: 1129  REVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDT 1188
              E T+D  SI++          Y +++        A I  +++    PP           
Sbjct: 20424 VENTTDLASILIKDADRLNSGCYELKLRNAMGSASATIRVQILDKPGPPGGPIEFKTVTA 20483

Query: 1189  GVLTVSWERSTTPD----ITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYN 1244
               +T+ W R    D    IT Y +    T+    + + E  H ++   T   +  G EY 
Sbjct: 20484 EKITLLW-RPPADDGGAKITHYIVEKRETSRVVWSMVSE--HLEECIITTTKIIKGNEYI 20540

Query: 1245  VSVYTVKDDKESVPI-SDTIIP-----AVPPPTDLRFTNIGPDTMRVTWAPP---PSIDL 1295
               V  V       P+ SD+++         PP     T I  ++M V W+ P      D+
Sbjct: 20541 FRVRAVNKYGIGEPLESDSVVAKNAFVTPGPPGIPEVTKITKNSMTVVWSRPIADGGSDI 20600

Query: 1296  TNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEY---VVSVSSVYEQHESTPLRG 1352
             + + +     K+      L  +  D    +T L   ++Y   V +V++  +   S P   
Sbjct: 20601 SGYFLEKRDKKSLGWFKVLKETIRDTRQKVTGLTENSDYQYRVCAVNAAGQGPFSEPSEF 20660

Query: 1353  RQKTGLDSPTG----IDFSDITANSFTVHWIAP----RATITGYRIRHHPEHFSGRPRED 1404
              +      P G    I  +D T +S T+ W  P     + +TGY +    E   G   E 
Sbjct: 20661 YKAADPIDPPGPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVV----EIRQGEEEEW 20716

Query: 1405  RVPHSRNSITLT-----NLTPGTEYVVSIVALN-GREESPLLIGQQSTVSDVPR----DL 1454
                 ++  +  T     NL PG  Y   + A+N   +  P+ + +     D+      DL
Sbjct: 20717 TTVSTKGEVRTTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQAKDILEAPEIDL 20776

Query: 1455  EVVAATPTSLLISWDA-----------PAVTVRYYRITYGETGGNSPVQEFTVPGSKSTA 1503
             +V   T        D            P VT R      G     S         S S  
Sbjct: 20777 DVALRTSVIAKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYS----IENTDSSSLL 20832

Query: 1504  TISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPS---QMQVTDVQDNSISV 1560
             TI  +         +    G G+  +S+  + +     +D P+   ++QV  V   ++++
Sbjct: 20833 TIPQVTRNDTGKYILTIENGVGEPKSSTVSVKV-----LDTPAACQKLQVKHVSRGTVTL 20887

Query: 1561  KWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGP-DQTEMTIEGLQPTVEYVVSVYAQ 1615
              W P      SP+  Y +    ++    T +  +     T   +  L     +   V A+
Sbjct: 20888 LWDPPLIDGGSPIINYVI--EKRDATKRTWSVVSHKCSSTSFKLIDLSEKTPFFFRVLAE 20945

Query: 1616  NPSGESQPLVQT---AVTNIDRP-KGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPED 1671
             N  G  +P   T       +  P + L+  D    S+ ++W  P          Y     
Sbjct: 20946 NEIGIGEPCETTEPVKAAEVPAPIRDLSMKDSTKTSVILSWTKPDFDGGSVITEYVVERK 21005

Query: 1672  GIHELFPAPDGEEDTAELQ--GLRPGSEYTVSVVALHDDMESQPL-IGTQSTAIPAPTDL 1728
             G  E   +  G   T E++   L+  S     V A ++   S P+ IG        P  +
Sbjct: 21006 GKGEQTWSHAGISKTCEIEVSQLKEQSVLEFRVFAKNEKGLSDPVTIG--------PITV 21057

Query: 1729  KFTQVTP-TSLSAQWTPPNVQLT---GYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMV 1784
             K   +TP   LS     P  Q+T   G+ V +    K  P   I+   D   +  S  + 
Sbjct: 21058 KELIITPEVDLS---DIPGAQVTVRIGHNVHLELPYKGKPKPSISWLKDGLPLKESEFVR 21114

Query: 1785  ATKYEVSV-YALKDTLTSRPAQ------------GVVTTLENVSPPRR----ARVTDATE 1827
              +K E  +  ++K+       +             V  T+  + PP +     R  +   
Sbjct: 21115 FSKTENKITLSIKNAKKEHGGKYTVILDNAVCRIAVPITVITLGPPSKPKGPIRFDEIKA 21174

Query: 1828  TTITISWRTKTET----ITGFQVDAVPANGQTPIQRTIKPDVR-SYTITGLQPGTDYKIY 1882
              ++ +SW    +     IT + ++      QT  +       R ++ +  L    +Y+  
Sbjct: 21175 DSVILSWDVPEDNGGGEITCYSIEK-RETSQTNWKMVCSSVARTTFKVPNLVKDAEYQFR 21233

Query: 1883  LYTLNDNARSSPVVIDASTA------IDAPSNLRFLATTPNSLLVSWQPP----RARITG 1932
             +   N    S P+V     A         P        T + + ++W  P     + +TG
Sbjct: 21234 VRAENRYGVSQPLVSSIIVAKHQFRIPGPPGKPVIYNVTSDGMSLTWDAPVYDGGSEVTG 21293

Query: 1933  YIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTV 1992
             + ++ ++  S   + V        E   TGL  G +Y   V A  +   S P    K T+
Sbjct: 21294 FHVEKKERNSILWQKVNTSPISGREYRATGLVEGLDYQFRVYAENSAGLSSPSDPSKFTL 21353

Query: 1993  QKTPFVTHPG 2002
               +P V  PG
Sbjct: 21354 AVSP-VDPPG 21362



 Score = 84.3 bits (207), Expect = 1e-15
 Identities = 337/1686 (19%), Positives = 592/1686 (35%), Gaps = 300/1686 (17%)

Query: 628   IQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISI 684
             + W+ P+    S I+ +I+  R    +  W++  I    +   I GL  G  Y+ ++I+ 
Sbjct: 8718  LNWSDPEDDGGSEITGFIIE-RKDAKMHTWRQP-IETERSKCDITGLLEGQEYKFRVIAK 8775

Query: 685   QQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWV--- 741
              ++G                PV    +        P      + TE T S+  + W    
Sbjct: 8776  NKFG-------------CGPPVEIGPILAVDPLGPPTSPERLTYTERTKSTITLDWKEPR 8822

Query: 742   -SASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQS 800
              +    + G+ +E    ++ D  +        TS  + +L   + Y   V  ++E GE  
Sbjct: 8823  SNGGSPIQGYIIEKRRHDKPDFERVNKRLCPTTSFLVENLDEHQMYEFRVKAVNEIGESE 8882

Query: 801   LILSTSQTTAPDAPPDPTVD---QVDDTSIVVRWSRP---QAPITGYRIVYSPSVEGSST 854
               L  +     D  P PT+     V   +I V+   P    A +TG  +   P +E S  
Sbjct: 8883  PSLPLNVVIQDDEVP-PTIKLRLSVRGDTIKVKAGEPVHIPADVTGLPM---PKIEWSKN 8938

Query: 855   E--LNLPETANSVTLSDLQPG-VQYNITI-YAVEENQESTPVVIQQETTGTPRS------ 904
             E  +  P  A  +T  ++     +  ++I  AV E++ +  V          R+      
Sbjct: 8939  ETVIEKPTDALQITKEEVSRSEAKTELSIPKAVREDKGTYTVTASNRLGSVFRNVHVEVY 8998

Query: 905   DTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPGEHGQRLPISRNT 960
             D    PR+L   ++      + W  P     S +T Y +D    +      + +    NT
Sbjct: 8999  DRPSPPRNLAVTDIKAESCYLTWDAPLDNGGSEITHYVIDKRDASRKKAEWEEVT---NT 9055

Query: 961   FAE----VTGLSPGVTYYFKV-----FAVSHGRESKPLTAQQTTKLDAPTNL-QFVNETD 1010
               E    +  L P   Y F+V     + +S   +S  +  Q   +L  P    + +  T 
Sbjct: 9056  AVEKRYGIWKLIPNGQYEFRVRAVNKYGISDECKSDKVVIQDPYRLPGPPGKPKVLARTK 9115

Query: 1011  STVLVRWTPP----RAQITGYRLTVGLTRRGQPRQY----------NVGPSVSKYPLRNL 1056
              ++LV WTPP     + ITGY     L +R +   Y           VG    ++ +  L
Sbjct: 9116  GSMLVSWTPPLDNGGSPITGY----WLEKREEGSPYWSRVSRAPITKVGLKGVEFNVPRL 9171

Query: 1057  QPASEYTVSLVAIKG------NQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPA 1110
                 +Y    +AI        ++ S           PG    P   + T+++I + W P 
Sbjct: 9172  LEGVKYQFRAMAINAAGIGPPSEPSDPEVAGDPIFPPGPPSCPEVKDKTKSSISLGWKPP 9231

Query: 1111  PRIGFKLGVRPSQG--GEAPREVTSD------------SGSIVVSGLTPGVEYVYTIQVL 1156
                  K G  P +G   E   E T+D            +   VV  L    +Y + ++ +
Sbjct: 9232  A----KDGGSPIKGYIVEMQEEGTTDWKRVNEPDKLITTCECVVPNLKELRKYRFRVKAV 9287

Query: 1157  RD-GQERDAPIVNKV-VTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPT- 1213
              + G+   +    ++  T +     + ++      ++  +  +   P +   R T   + 
Sbjct: 9288  NEAGESEPSDTTGEIPATDIQEEPEVFIDIGAQDCLVCKAGSQIRIPAVIKGRPTPKSSW 9347

Query: 1214  --NGQQGNSLEEVVH---ADQSSCTFDNLSPGL----------EYNVSVYTVKDDKESVP 1258
               +G+   ++++ VH    D    T +N S  +          +Y+++    K  +++  
Sbjct: 9348  EFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECKRSHTGKYSITAKN-KAGQKTAN 9406

Query: 1259  ISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEED-VAELSIS 1317
                 ++    PP DL+ ++I   + R++W  P   D  + +  Y   K   D  A   ++
Sbjct: 9407  CRVKVMDVPGPPKDLKVSDITRGSCRLSWKMPDD-DGGDRIKGYVIEKRTIDGKAWTKVN 9465

Query: 1318  P--SDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGL-------DSPTGIDFSD 1368
             P       V+ +LL   +Y   V +        P+   Q+T         D P  +    
Sbjct: 9466  PDCGSTTFVVPDLLSEQQYFFRVRAENRFGIGPPVETIQRTTARDPIYPPDPPIKLKIGL 9525

Query: 1369  ITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPRED-RVPHSRN----SITLTNLT 1419
             IT N+  + W  P+    + +T Y +       +G  +E  R  + R+      T+ +L 
Sbjct: 9526  ITKNTVHLSWKPPKNDGGSPVTHYIVECLAWDPTGTKKEAWRQCNKRDVEELQFTVEDLV 9585

Query: 1420  PGTEYVVSIVALN--GREESPLLIG-------QQSTVSDVPRDLEVVAATPTSLLIS-WD 1469
              G EY   + A+N  G  +    +G             D+   +EV   T  +++     
Sbjct: 9586  EGGEYEFRVKAVNAAGVSKPSATVGPCDCQRPDMPPSIDLKEFMEVEEGTNVNIVAKIKG 9645

Query: 1470  APAVTVRYYRITYGETGGNSPVQEFT-----VPGSKSTATISGLKPGVDYTITVYAVTGR 1524
              P  T+ +++    +     PV   T     V     T  I   +       T+ AV   
Sbjct: 9646  VPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDTGLYTITAVNNL 9705

Query: 1525  GDSPASSKPISINYRTEIDKP-SQMQVTDVQDNSISVKWLP----SSSPVTGYRVTTTPK 1579
             G    +SK + +N       P   ++   V  + +++ W P      S +T Y +     
Sbjct: 9706  G---TASKEMRLNVLGRPGPPVGPIKFESVSADQMTLSWFPPKDDGGSKITNYVIEKREA 9762

Query: 1580  NGPGPTKT---KTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVT--NI-- 1632
             N     KT    ++ P +   TI  L    EYV  + AQN  G  +PL     T  N+  
Sbjct: 9763  N----RKTWVHVSSEPKECTYTIPKLLEGHEYVFRIMAQNKYGIGEPLDSEPETARNLFS 9818

Query: 1633  --DRPKGLAFTDVDVDSIKIAWESPQ----GQVSRYRVTYSSPEDGIHELFPAPDGEEDT 1686
                 P     + V  +S+ + WE P+      V+ Y   +   +D   + +   + +   
Sbjct: 9819  VPGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPVTGY---WLEMKDTTSKRWKRVNRDPIK 9875

Query: 1687  A-------ELQGLRPGSEYTVSVVALH------DDMESQPLIGTQSTAIPAPTDLKFTQV 1733
             A       ++ GL  GS+Y   V A++        + S P       A P P   K T  
Sbjct: 9876  AMTLGVSYKVTGLIEGSDYQFRVYAINAAGVGPASLPSDPATARDPIAPPGPPFPKVTDW 9935

Query: 1734  TPTSLSAQWTPP----NVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYE 1789
             T +S   +W+PP      ++TGY V    + K    K  +     + +VV+GL     Y+
Sbjct: 9936  TKSSADLEWSPPLKDGGSKVTGYIVEYKEEGKEEWEKGKDKEVRGTKLVVTGLKEGAFYK 9995

Query: 1790  VSVYALKDTLTSRPAQGVVTTLEN----VSPPRR--ARVTD----------------ATE 1827
               V A+       P + V   +E     VSP  +  A V D                + +
Sbjct: 9996  FRVRAVNIAGIGEPGE-VTDVIEMKDRLVSPDLQLDASVRDRIVVHAGGVIRIIAYVSGK 10054

Query: 1828  TTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDV--RSYTITGLQPGTDYKIYLYT 1885
                T++W     T+              P + TI+      S  I   Q        L  
Sbjct: 10055 PPPTVTWNMNERTL--------------PQEATIETTAISSSMVIKNCQRSHQGVYSLLA 10100

Query: 1886  LNDNARSSPVVIDASTAIDAPSNLRFLA--TTPNSLLVSWQPPR----ARITGYIIKYEK 1939
              N+       +I     +  P    FLA   T  S  ++W  P     + IT Y+I  EK
Sbjct: 10101 KNEAGERKKTIIVDVLDVPGPVGTPFLAHNLTNESCKLTWFSPEDDGGSPITNYVI--EK 10158

Query: 1940  PGSPPREVVPRPRPGVTE-ATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQKTPFV 1998
               S  R   P       + AT+ GL  G  Y   + A             + ++   PFV
Sbjct: 10159 RESDRRAWTPVTYTVTRQNATVQGLIQGKAYFFRIAA-------------ENSIGMGPFV 10205

Query: 1999  THPGYDTGNGIQLPGTSGQQPSVGQQMIFEEHGFRRTTPPTTATPIRHRPRPYPPNVGQE 2058
                                     + ++  E             PI    RP    V + 
Sbjct: 10206 ---------------------ETSEALVIRE-------------PITVPERPEDLEVKEV 10231

Query: 2059  ALSQTTISWAP--FQDTSE---YIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYN 2113
               +  T++W P  +   SE   Y++    +GT++          S   T+ GL  G TY 
Sbjct: 10232 TKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEKFHKVTNDNLLSRKYTVKGLKEGDTYE 10291

Query: 2114  IIVEAL 2119
               V A+
Sbjct: 10292 YRVSAV 10297



 Score = 84.3 bits (207), Expect = 1e-15
 Identities = 134/644 (20%), Positives = 244/644 (37%), Gaps = 79/644 (12%)

Query: 1421  GTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAP----AVTVR 1476
             G +Y++    + G +  P+ +            ++V   T     ++W  P       + 
Sbjct: 17196 GGQYILRASNVAGSKSFPVNVKVLDRPGPPEGPVQVTGVTSEKCSLTWSPPLQDGGSDIS 17255

Query: 1477  YYRITYGETGGNSPVQEFTVPGSK---STATISGLKPGVDYTITVYAVTGRG-DSPASSK 1532
             +Y +   ET   +    +TV  S+   ++  ++ L  G +Y   + AV   G   P  S 
Sbjct: 17256 HYVVEKRETSRLA----WTVVASEVVTNSLKVTKLLEGNEYVFRIMAVNKYGVGEPLESA 17311

Query: 1533  PISINYRTEID-KPSQMQVTDVQDNSISVKW-LPSS---SPVTGYRVTTTPKNGPGPTKT 1587
             P+ +     +   P  ++VT++  +S++V W  P S   S + GY V    ++G    K 
Sbjct: 17312 PVLMKNPFVLPGPPKSLEVTNIAKDSMTVCWNRPDSDGGSEIIGYIVEKRDRSGIRWIKC 17371

Query: 1588  KTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTA-------VTNIDRPKGLAF 1640
                      + + GL    EY   V A+N +G  +P   T        V     P     
Sbjct: 17372 NKRRITDLRLRVTGLTEDHEYEFRVSAENAAGVGEPSPATVYYKACDPVFKPGPPTNAHI 17431

Query: 1641  TDVDVDSIKIAWESP----QGQVSRYRVTYSSPEDGIHELFPAPDGEEDTA-ELQGLRPG 1695
              D   +SI +AW  P      ++  Y V     ++   ++     G   T  E+  L   
Sbjct: 17432 VDTTKNSITLAWGKPIYDGGSEILGYVVEICKADEEEWQIVTPQTGLRVTRFEISKLTEH 17491

Query: 1696  SEYTVSVVALHDDMESQPLIGT-QSTAIPAPTDLKFTQVTPT-SLSAQWTPPNVQLTGYR 1753
              EY + V AL+        +G  ++T++P     +     P   L ++     V   G  
Sbjct: 17492 QEYKIRVCALNK-------VGLGEATSVPGTVKPEDKLEAPELDLDSELRKGIVVRAGGS 17544

Query: 1754  VRVTPKEKTGPMKEINLAPD----SSSVVVSGLMVATKYEVS----------VYALKDTL 1799
              R+    K  P  EI  + +    +  V +   +  T+  +           +  L+++ 
Sbjct: 17545 ARIHIPFKGRPTPEITWSREEGEFTDKVQIEKGVNYTQLSIDNCDRNDAGKYILKLENSS 17604

Query: 1800  TSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKT----ETITGFQVDAVPANGQT 1855
              S+ A   V  L+   PP+   V +  + +  + W          +  + +D   +  + 
Sbjct: 17605 GSKSAFVTVKVLDTPGPPQNLAVKEVRKDSAFLVWEPPIIDGGAKVKNYVIDKRESTRKA 17664

Query: 1856  PIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPV-VIDASTAIDAPS-----NL 1909
                 + K    S+ +  L  G  Y   +   N+     PV  +DA  A + PS      L
Sbjct: 17665 YANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFGVGVPVETVDAVKAAEPPSPPGKVTL 17724

Query: 1910  RFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEP 1965
               ++ T  SL+  W+ P     +R+ GY+++ +  G+    +V   +  V  A +TGL  
Sbjct: 17725 TDVSQTSASLM--WEKPEHDGGSRVLGYVVEMQPKGTEKWSIVAESK--VCNAVVTGLSS 17780

Query: 1966  GTEYTIYVIALKNNQKSE------PLIGRKKTVQ---KTPFVTH 2000
             G EY   V A     KS+      P+I +  T+Q   K PF T+
Sbjct: 17781 GQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKLPFNTY 17824



 Score = 82.4 bits (202), Expect = 5e-15
 Identities = 130/589 (22%), Positives = 217/589 (36%), Gaps = 70/589 (11%)

Query: 1505  ISGLKPGVDYTITVYAVTGRG-DSPASSKPI-SINYRTEIDKPSQMQVTDVQDNSISVKW 1562
             ++ L  G +YT  + AV   G   P  S+P+ + N     D P   +VT V  +S+ V W
Sbjct: 16201 VTKLLEGNEYTFRIMAVNKYGVGEPLESEPVVAKNPFVVPDAPKAPEVTTVTKDSMIVVW 16260

Query: 1563  -LPSS---SPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPS 1618
               P+S   S + GY +    K G   T+       +  + + GL    +Y   V A+N +
Sbjct: 16261 ERPASDGGSEILGYVLEKRDKEGIRWTRCHKRLIGELRLRVTGLIENHDYEFRVSAENAA 16320

Query: 1619  GESQPLVQTA-------VTNIDRPKGLAFTDVDVDSIKIAWESP----QGQVSRYRVTYS 1667
             G S+P   +A       +     P      D+   S+ ++W  P      ++  Y V   
Sbjct: 16321 GLSEPSPPSAYQKACDPIYKPGPPNNPKVIDITRSSVFLSWSKPIYDGGCEIQGYIVEKC 16380

Query: 1668  SPEDGIHELFPAPDGEEDT-AELQGLRPGSEYTVSVVAL-------HDDMESQPLIGTQS 1719
                 G   +   P G   T  E++ L    EY   + A+       H D+    ++  + 
Sbjct: 16381 DVSVGEWTMCTPPTGINKTNIEVEKLLEKHEYNFRICAINKAGVGEHADVPGPIIVEEKL 16440

Query: 1720  TAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEK----TGPMKEINLAPDSS 1775
              A     DL+  ++                   + R TP+ K     G +++  +   +S
Sbjct: 16441 EAPDIDLDLELRKIINIRAGGSLR----LFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTS 16496

Query: 1776  SVVVSGLMVATKYEVSVY--ALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITIS 1833
             S     L    +Y+   Y   L+++  ++ A   V  L+  SPP   +VT+ T+ +++I+
Sbjct: 16497 SFTSLVLDNVNRYDSGKYTLTLENSSGTKSAFVTVRVLDTPSPPVNLKVTEITKDSVSIT 16556

Query: 1834  WRTKT----ETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDN 1889
             W          I  + V+   A  ++           S+ I  LQ G  Y   +   N+ 
Sbjct: 16557 WEPPLLDGGSKIKNYIVEKREATRKSYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAENEY 16616

Query: 1890  ARSSPV----VIDASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPG 1941
                 P      I  +     P  +     T NS+ +SW  P     ++I  YI++ +   
Sbjct: 16617 GIGLPAQTADPIKVAEVPQPPGKITVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKH 16676

Query: 1942  SPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQKTPFVTHP 2001
             S       R +    +A IT L  G EY   V+A+    +S+P       V K   V  P
Sbjct: 16677 SEKWSECARVKS--LQAVITNLTQGEEYLFRVVAVNEKGRSDPRSLAVPIVAK-DLVIEP 16733

Query: 2002  GYDTGNGIQLPGTSGQQPSVGQQMIFEEHGFRRTTPPTTATPIRHRPRP 2050
                       P  S     VGQ +  E              PI  RP+P
Sbjct: 16734 DVK-------PAFSSYSVQVGQDLKIE-------------VPISGRPKP 16762



 Score = 82.0 bits (201), Expect = 6e-15
 Identities = 266/1310 (20%), Positives = 442/1310 (33%), Gaps = 219/1310 (16%)

Query: 731   ITASSFVVSWVSASDTVSGFRVEYELSE-EGDEPQYLDLPSTAT--SVNIPDLLPGRKYI 787
             ++A    +SW    D        Y + + E +   ++ + S     +  IP LL G +Y+
Sbjct: 9732  VSADQMTLSWFPPKDDGGSKITNYVIEKREANRKTWVHVSSEPKECTYTIPKLLEGHEYV 9791

Query: 788   V-----NVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ----API 838
                   N Y I E  +     + +  + P AP  PTV  V   S+ V W  P+    +P+
Sbjct: 9792  FRIMAQNKYGIGEPLDSEPETARNLFSVPGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPV 9851

Query: 839   TGYRIVYSPSVEGSSTELNLPETANSVTL------SDLQPGVQYNITIYAVEENQESTPV 892
             TGY +    +       +N  +   ++TL      + L  G  Y   +YA+       P 
Sbjct: 9852  TGYWLEMKDTTSKRWKRVN-RDPIKAMTLGVSYKVTGLIEGSDYQFRVYAINAAGVG-PA 9909

Query: 893   VIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPG 948
              +  +          P P   +  + T     + W+PP     S VTGY V+        
Sbjct: 9910  SLPSDPATARDPIAPPGPPFPKVTDWTKSSADLEWSPPLKDGGSKVTGYIVEYKEEGKEE 9969

Query: 949   EHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGR-----------ESKPLTAQQTTKL 997
                 +    R T   VTGL  G  Y F+V AV+              E K        +L
Sbjct: 9970  WEKGKDKEVRGTKLVVTGLKEGAFYKFRVRAVNIAGIGEPGEVTDVIEMKDRLVSPDLQL 10029

Query: 998   DAPTNLQFVNETDSTV----LVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSV--SKY 1051
             DA    + V      +     V   PP        +T  +  R  P++  +  +   S  
Sbjct: 10030 DASVRDRIVVHAGGVIRIIAYVSGKPPPT------VTWNMNERTLPQEATIETTAISSSM 10083

Query: 1052  PLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNT-EVTETTIVITWTP- 1109
              ++N Q + +   SL+A     E  K   V     PG    P+    +T  +  +TW   
Sbjct: 10084 VIKNCQRSHQGVYSLLAKNEAGERKKTIIVDVLDVPGPVGTPFLAHNLTNESCKLTWFSP 10143

Query: 1110  -----APRIGFKLGVRPS-QGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRD----- 1158
                  +P   + +  R S +    P   T    +  V GL  G  Y + I          
Sbjct: 10144 EDDGGSPITNYVIEKRESDRRAWTPVTYTVTRQNATVQGLIQGKAYFFRIAAENSIGMGP 10203

Query: 1159  -GQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSW---ERSTTPDITGYRITTTPTN 1214
               +  +A ++ + +T    P +L ++       +T++W   +     +I  Y + +    
Sbjct: 10204 FVETSEALVIREPITVPERPEDLEVK-EVTKNTVTLTWNPPKYDGGSEIINYVLESRLIG 10262

Query: 1215  GQQGNSLEEVVHADQSSCTFDNLSPG--LEYNVSVYTV----KDDKESVPISDTIIPAVP 1268
              ++ + +    +      T   L  G   EY VS   +    K    + PI  T    + 
Sbjct: 10263 TEKFHKVTN-DNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGKPSFCTKPI--TCKDELA 10319

Query: 1269  PPT---------DLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAE---LSI 1316
             PPT          +R       T R +  P P +         S  K+E DV E     I
Sbjct: 10320 PPTLHLDFRDKLTIRVGEAFALTGRYSGKPKPKV---------SWFKDEADVLEDDRTHI 10370

Query: 1317  SPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSP----TGIDFSDITAN 1372
               +   + L  +            V E    +     Q   +D P      + F ++T +
Sbjct: 10371 KTTPATLALEKIKAKRSDSGKYCVVVENSTGSRKGFCQVNVVDRPGPPVGPVSFDEVTKD 10430

Query: 1373  SFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVP----HSRNSITLTNLTPGTEYVVSI 1428
                + W  P     G +I ++        ++  +P     ++ +  ++ L  G +Y+  I
Sbjct: 10431 YMVISW-KPPLDDGGSKITNYIIEKKEVGKDVWMPVTSASAKTTCKVSKLLEGKDYIFRI 10489

Query: 1429  VALNGREESPLLIG------QQSTVSDVPRDLEVVAATPTSLLISWDAP----------- 1471
              A N    S  L+        +  V D P    V   T  S L++W+ P           
Sbjct: 10490 HAENLYGISDPLVSDSMKAKDRFRVPDAPDQPIVTEVTKDSALVTWNKPHDGGKPITNYI 10549

Query: 1472  -----AVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVT--GR 1524
                   ++ R+ R+T        P  +F VP          L  G  Y   V A    G 
Sbjct: 10550 LEKRETMSKRWARVTKDPI---HPYTKFRVP---------DLLEGCQYEFRVSAENEIGI 10597

Query: 1525  GDSPASSKPISINYRTEIDKPS---QMQVTDVQDNSISVKWLP----SSSPVTGYRVTTT 1577
             GD    SKP+    +  I KPS     +  D   NS+ + W P      S + GY +   
Sbjct: 10598 GDPSPPSKPVFA--KDPIAKPSPPVNPEAIDTTCNSVDLTWQPPRHDGGSKILGY-IVEY 10654

Query: 1578  PKNGPGPTKTKTAGPD---QTEMTIEGLQPTVEYVVSVYAQNPSGESQP-------LVQT 1627
              K G    +     P+   +T+  + GL+    Y   V A N +GES P       LV+ 
Sbjct: 10655 QKVGDEEWRRANHTPESCPETKYKVTGLRDGQTYKFRVLAVNAAGESDPAHVPEPVLVKD 10714

Query: 1628  AV--------TNIDRPKGLAFTDV--------DVDSIKIAWESPQGQVSRYRVTYSSPED 1671
              +         N+ R + +   D          V   K+ W+              +P  
Sbjct: 10715 RLEPPELILDANMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARIDVTPVG 10774

Query: 1672  GIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFT 1731
                E+  A   +     L    P    TVSV  L  D                P DL+ +
Sbjct: 10775 SKLEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDKPG------------PPRDLEVS 10822

Query: 1732  QVTPTSLSAQWTPP----NVQLTGYRVR-------------VTPKEKTGPMKEINLAPDS 1774
             ++   S    W  P       +T Y V               T K+K+   K +N     
Sbjct: 10823 EIRKDSCYLTWKEPLDDGGSVITNYVVERRDVASAQWSPLSATSKKKSHFAKHLN----E 10878

Query: 1775  SSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISW 1834
              +  +  +    +Y    +      T +P +  +  L    PP+     D  +T +++ W
Sbjct: 10879 GNQYLFRVAAENQYGRGPF----VETPKPIK-ALDPLHPPGPPKDLHHVDVDKTEVSLVW 10933

Query: 1835  ----RTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYK 1880
                 R     ITG+ V+      Q  I+     ++    +TGLQ G  Y+
Sbjct: 10934 NKPDRDGGSPITGYLVEYQEEGTQDWIKFKTVTNLEC-VVTGLQQGKTYR 10982



 Score = 80.9 bits (198), Expect = 1e-14
 Identities = 248/1194 (20%), Positives = 435/1194 (36%), Gaps = 142/1194 (11%)

Query: 908   PSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAE 963
             P    +Q   VT  K ++ W+PP     S ++ Y V+    +          +  N+  +
Sbjct: 17224 PPEGPVQVTGVTSEKCSLTWSPPLQDGGSDISHYVVEKRETSRLAWTVVASEVVTNSL-K 17282

Query: 964   VTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDA------PTNLQFVNETDSTVLVRW 1017
             VT L  G  Y F++ AV+     +PL +      +       P +L+  N    ++ V W
Sbjct: 17283 VTKLLEGNEYVFRIMAVNKYGVGEPLESAPVLMKNPFVLPGPPKSLEVTNIAKDSMTVCW 17342

Query: 1018  TPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQ---------PASEYTVSLVA 1068
               P +   G    +G     + R        +K  + +L+            E+ VS   
Sbjct: 17343 NRPDSD--GGSEIIGYIVEKRDRSGIRWIKCNKRRITDLRLRVTGLTEDHEYEFRVSAEN 17400

Query: 1069  IKGNQESPKATGVFTTLQPGSSI-PPYNTEVTETT---IVITWTP------APRIGFKLG 1118
               G  E   AT  +    P     PP N  + +TT   I + W        +  +G+ + 
Sbjct: 17401 AAGVGEPSPATVYYKACDPVFKPGPPTNAHIVDTTKNSITLAWGKPIYDGGSEILGYVVE 17460

Query: 1119  VRPSQGGEAPREVTSDSGSIV----VSGLTPGVEYVYTIQVLRD---GQERDAPIVNKVV 1171
             +  +   E  + VT  +G  V    +S LT   EY   +  L     G+    P   K  
Sbjct: 17461 ICKADEEEW-QIVTPQTGLRVTRFEISKLTEHQEYKIRVCALNKVGLGEATSVPGTVKPE 17519

Query: 1172  TPLSPPTNLHLEANPDTGVLT---------VSWERSTTPDITGYRITTTPTNGQQGNSLE 1222
               L  P  L L++    G++          + ++   TP+IT  R     T+  Q   +E
Sbjct: 17520 DKLEAP-ELDLDSELRKGIVVRAGGSARIHIPFKGRPTPEITWSREEGEFTDKVQ---IE 17575

Query: 1223  EVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRFTNIGPDT 1282
             + V+  Q S    + +   +Y + +      K +  ++  ++    PP +L    +  D+
Sbjct: 17576 KGVNYTQLSIDNCDRNDAGKYILKLENSSGSKSAF-VTVKVLDTPGPPQNLAVKEVRKDS 17634

Query: 1283  MRVTWAPPPSIDLTNFLVRYSPVKNEED---VAELSISPSDNAVVLTNLLPGTEYVVSVS 1339
               + W PP  ID    +  Y   K E      A +S   S  +  + NL  G  Y   V 
Sbjct: 17635 AFLVWEPP-IIDGGAKVKNYVIDKRESTRKAYANVSSKCSKTSFKVENLTEGAIYYFRVM 17693

Query: 1340  SVYEQHESTPLR---GRQKTGLDSPTG-IDFSDITANSFTVHWIAPR----ATITGYRIR 1391
             +  E     P+      +     SP G +  +D++  S ++ W  P     + + GY + 
Sbjct: 17694 AENEFGVGVPVETVDAVKAAEPPSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVE 17753

Query: 1392  HHPEHFSGRPREDRVPHSRN-SITLTNLTPGTEYVVSIVALNGREES-PLLIGQQSTVSD 1449
               P+   G  +   V  S+  +  +T L+ G EY   + A N + +S P ++G      D
Sbjct: 17754 MQPK---GTEKWSIVAESKVCNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKD 17810

Query: 1450  VPRDLEVVAATPTSLL-----ISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTAT 1504
             +     +     T  +     +  + P +      I++ + G   P+++ T    + TAT
Sbjct: 17811 LTIQPSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDG--EPLKQTTRVNVEETAT 17868

Query: 1505  --ISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKP-SQMQVTDVQDNSISVK 1561
               +  +K G       Y VT    +  +++ +S+    +   P   ++  +V  + + + 
Sbjct: 17869 STVLHIKEGNKDDFGKYTVTATNSAGTATENLSVIVLEKPGPPVGPVRFDEVSADFVVIS 17928

Query: 1562  WLPSS----SPVTGYRV-----TTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSV 1612
             W P +      ++ Y V     TTT  +    T  +T       + I  L+   EY   +
Sbjct: 17929 WEPPAYTGGCQISNYIVEKRDTTTTTWHMVSATVARTT------IKITKLKTGTEYQFRI 17982

Query: 1613  YAQNPSGESQPLVQTAVT-----NIDRPKGLAF-TDVDVDSIKIAWESPQGQVSRYRVTY 1666
             +A+N  G+S PL   AV          P G  F T +  D + + W  P        + Y
Sbjct: 17983 FAENRYGKSAPLDSKAVIVQYPFKEPGPPGTPFVTSISKDQMLVQWHEPVNDGGTKIIGY 18042

Query: 1667  SSPEDGIHELF-------PAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQS 1719
                +   + +        P  D +  T    GL  G EY   V A +     +P   ++ 
Sbjct: 18043 HLEQKEKNSILWVKLNKTPIQDTKFKTT---GLDEGLEYEFKVSAENIVGIGKPSKVSEC 18099

Query: 1720  TAIPAPTDL----KFTQVTPTSLSAQWTPP----NVQLTGYRVRVTPKEKTGPMKEINLA 1771
                  P D     +   +T  +++ +W  P      ++TGY V          MK     
Sbjct: 18100 FVARDPCDPPGRPEAIVITRNNVTLKWKKPAYDGGSKITGYIVEKKDLPDGRWMKASFTN 18159

Query: 1772  PDSSSVVVSGLMVATKYEVSVYALKDTLT-SRPAQ--GVVTTLENVSPPRRAR------- 1821
                +   VSGL+   +YE  V A       S P+   G +T  + +  P  +        
Sbjct: 18160 VLETEFTVSGLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARDEIDAPNASLDPKYKDV 18219

Query: 1822  -VTDATET-TITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQP-GTD 1878
              V  A ET  +    R K      +  D      +T  +  IK  ++  T+       TD
Sbjct: 18220 IVVHAGETFVLEADIRGKPIPDVVWSKDGKELE-ETAARMEIKSTIQKTTLVVKDCIRTD 18278

Query: 1879  YKIYLYTLND--NARSSPVVIDASTAIDAPSN-LRFLATTPNSLLVSWQPPR----ARIT 1931
                Y+  L++    +S P+ +        P   L+    T     ++W PP     A I+
Sbjct: 18279 GGQYILKLSNVGGTKSIPITVKVLDRPGPPEGPLKVTGVTAEKCYLAWNPPLQDGGANIS 18338

Query: 1932  GYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPL 1985
              YII+  +        V      +    +T L PG EY   V+A+      EPL
Sbjct: 18339 HYIIEKRETSRLSWTQVSTEVQALNYK-VTKLLPGNEYIFRVMAVNKYGIGEPL 18391



 Score = 78.6 bits (192), Expect = 7e-14
 Identities = 169/767 (22%), Positives = 275/767 (35%), Gaps = 120/767 (15%)

Query: 601   PLQTYPSSSGPVEVFITETPSQPN-------SHPIQWNAPQ---PSHISKYILRWRPKNS 650
             P +T P       VF+   PS+P        +  I W  P     + I+ Y + ++  + 
Sbjct: 19571 PSETSPLIRAEDPVFLPSPPSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEYKKSDD 19630

Query: 651   VGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNT 710
                WK +        YTI GL  G  Y  ++ S+ + G  +        + +S P  +  
Sbjct: 19631 TD-WKTSIQSLRGTEYTISGLTTGAEYVFRVKSVNKVGASD-------PSDSSDPQIAKE 19682

Query: 711   VTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVS--GFRVEYELSEEGDEP----Q 764
                E     PL       +E+  +  V +  S + TV   G  V   L  + D       
Sbjct: 19683 REEE-----PLFDID---SEMRKTLIVKAGASFTMTVPFRGRPVPNVLWSKPDTDLRTRA 19734

Query: 765   YLDLPSTATSVNIPDLL--PGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQV 822
             Y+D   + TS+ I +       KY + +  +      +L++    T  P  P + TV  V
Sbjct: 19735 YVDTTDSRTSLTIENANRNDSGKYTLTIQNVLSAASLTLVVKVLDTPGP--PTNITVQDV 19792

Query: 823   DDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNI 878
                S V+ W  P+    AP+  Y I    + + +   +       S  +++LQ G  Y  
Sbjct: 19793 TKESAVLSWDVPENDGGAPVKNYHIEKREASKKAWVSVTNNCNRLSYKVTNLQEGAIYYF 19852

Query: 879   TIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAV 934
              +    E     P   ++   G   ++    P  L    ++   V++ W  PE    S +
Sbjct: 19853 RVSGENEFGVGIPAETKE---GVKITEKPSPPEKLGVTSISKDSVSLTWLKPEHDGGSRI 19909

Query: 935   TGYRVDVIPVNLPGEHGQR----LPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKP-- 988
               Y V+ +      E GQ+      ++++T   V+GL     Y+F+VFA +    S P  
Sbjct: 19910 VHYVVEAL------EKGQKNWVKCAVAKSTHHVVSGLRENSEYFFRVFAENQAGLSDPRE 19963

Query: 989   -LTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPS 1047
              L      +   P  +   N    TV VR         G  L V +   G+P    V  S
Sbjct: 19964 LLLPVLIKEQLEPPEIDMKNFPSHTVYVR--------AGSNLKVDIPISGKPLP-KVTLS 20014

Query: 1048  VSKYPLR-NLQPASEYTV---------SLVAIKGNQESPKATGVFTTL---------QPG 1088
                 PL+  ++  +E T          S+ A  G  E   A    TT          +PG
Sbjct: 20015 RDGVPLKATMRFNTEITAENLTINLKESVTADAGRYEITAANSSGTTKAFINIVVLDRPG 20074

Query: 1089  SSI-PPYNTEVTETTIVITWTPAPRIG-------FKLGVRPSQGGEAPREVTSDSGSIVV 1140
                 P   +++TE ++ + W P    G         L    S         T     + V
Sbjct: 20075 PPTGPVVISDITEESVTLKWEPPKYDGGSQVTNYILLKRETSTAVWTEVSATVARTMMKV 20134

Query: 1141  SGLTPGVEYVYTIQV-----LRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSW 1195
               LT G EY + I+      + D  +     V    T   PP+   +  N     +TV W
Sbjct: 20135 MKLTTGEEYQFRIKAENRFGISDHIDSACVTVKLPYTTPGPPSTPWV-TNVTRESITVGW 20193

Query: 1196  ERSTT---PDITGYRITTTPTNG---QQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYT 1249
                 +     + GY +     N    Q+ N L  V+       T   +S GL Y   VY 
Sbjct: 20194 HEPVSNGGSAVVGYHLEMKDRNSILWQKANKL--VIRTTHFKVT--TISAGLIYEFRVYA 20249

Query: 1250  V------KDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPP 1290
                    K    S P+    I A  PP ++R T+I  +++ ++W  P
Sbjct: 20250 ENAAGVGKPSHPSEPV--LAIDACEPPRNVRITDISKNSVSLSWQQP 20294



 Score = 77.8 bits (190), Expect = 1e-13
 Identities = 327/1588 (20%), Positives = 561/1588 (35%), Gaps = 285/1588 (17%)

Query: 737   VVSWVSASDT----VSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQ 792
             +++W    D     ++GF +E + ++     Q ++  +  +  +I  LL G++Y   V  
Sbjct: 8717  LLNWSDPEDDGGSEITGFIIERKDAKMHTWRQPIE--TERSKCDITGLLEGQEYKFRVIA 8774

Query: 793   ISEDG-----EQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQA----PITGYRI 843
              ++ G     E   IL+      P +P   T  +   ++I + W  P++    PI GY I
Sbjct: 8775  KNKFGCGPPVEIGPILAVDPLGPPTSPERLTYTERTKSTITLDWKEPRSNGGSPIQGYII 8834

Query: 844   VY----SPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTP-----VVI 894
                    P  E  +  L  P T  S  + +L     Y   + AV E  ES P     VVI
Sbjct: 8835  EKRRHDKPDFERVNKRL-CPTT--SFLVENLDEHQMYEFRVKAVNEIGESEPSLPLNVVI 8891

Query: 895   QQETTG-------TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLP 947
             Q +          + R DT+     ++  E   +   +   P           VI     
Sbjct: 8892  QDDEVPPTIKLRLSVRGDTIK----VKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTD 8947

Query: 948   GEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSH----GRESKPLTAQQTTKLDAPTNL 1003
                  +  +SR+       +   V      + V+     G   + +  +   +   P NL
Sbjct: 8948  ALQITKEEVSRSEAKTELSIPKAVREDKGTYTVTASNRLGSVFRNVHVEVYDRPSPPRNL 9007

Query: 1004  QFVNETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSV--SKYPLRNLQ 1057
                +    +  + W  P     ++IT Y +      R +     V  +    +Y +  L 
Sbjct: 9008  AVTDIKAESCYLTWDAPLDNGGSEITHYVIDKRDASRKKAEWEEVTNTAVEKRYGIWKLI 9067

Query: 1058  PASEYTVSLVAIKGNQESPKATGVFTTLQ-----PGSSIPPYNTEVTETTIVITWTP--- 1109
             P  +Y   + A+     S +       +Q     PG    P     T+ +++++WTP   
Sbjct: 9068  PNGQYEFRVRAVNKYGISDECKSDKVVIQDPYRLPGPPGKPKVLARTKGSMLVSWTPPLD 9127

Query: 1110  ---APRIGFKLGVRP------SQGGEAPREVTSDSG-SIVVSGLTPGVEYVYTIQVLR-- 1157
                +P  G+ L  R       S+   AP       G    V  L  GV+Y +    +   
Sbjct: 9128  NGGSPITGYWLEKREEGSPYWSRVSRAPITKVGLKGVEFNVPRLLEGVKYQFRAMAINAA 9187

Query: 1158  ----DGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWE---RSTTPDITGYRITT 1210
                   +  D  +    + P  PP+   ++    + + ++ W+   +     I GY +  
Sbjct: 9188  GIGPPSEPSDPEVAGDPIFPPGPPSCPEVKDKTKSSI-SLGWKPPAKDGGSPIKGYIVEM 9246

Query: 1211  TP---TNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAV 1267
                  T+ ++ N  ++++   +  C   NL    +Y   V  V +  ES P SDT     
Sbjct: 9247  QEEGTTDWKRVNEPDKLITTCE--CVVPNLKELRKYRFRVKAVNEAGESEP-SDTT--GE 9301

Query: 1268  PPPTDLR-----FTNIGPDTMRVTWA-------------PPPS----IDLTNFLVRYSPV 1305
              P TD++     F +IG     V  A             P P      D          V
Sbjct: 9302  IPATDIQEEPEVFIDIGAQDCLVCKAGSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGV 9361

Query: 1306  KNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTP-LRGRQKTGLDSPTGI 1364
              +  + A+L  + + + +++           S+++  +  + T   R +       P  +
Sbjct: 9362  HDIPEDAQLETAENSSVIIIPECKRSHTGKYSITAKNKAGQKTANCRVKVMDVPGPPKDL 9421

Query: 1365  DFSDITANSFTVHWIAPRAT----ITGYRIRHHPEHFSGRPREDRVPH-SRNSITLTNLT 1419
               SDIT  S  + W  P       I GY I        G+      P     +  + +L 
Sbjct: 9422  KVSDITRGSCRLSWKMPDDDGGDRIKGYVIEKRT--IDGKAWTKVNPDCGSTTFVVPDLL 9479

Query: 1420  PGTEYVVSIVALNGREESPLLIGQQSTVS-------DVPRDLEVVAATPTSLLISWDAPA 1472
                +Y   + A N     P +   Q T +       D P  L++   T  ++ +SW  P 
Sbjct: 9480  SEQQYFFRVRAENRFGIGPPVETIQRTTARDPIYPPDPPIKLKIGLITKNTVHLSWKPP- 9538

Query: 1473  VTVRYYRITYGETGGNSPVQEFTVP-------GSKSTA--------------TISGLKPG 1511
                        +  G SPV  + V        G+K  A              T+  L  G
Sbjct: 9539  -----------KNDGGSPVTHYIVECLAWDPTGTKKEAWRQCNKRDVEELQFTVEDLVEG 9587

Query: 1512  VDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTG 1571
              +Y   V AV   G S  S+             P   Q  D+   SI +K        T 
Sbjct: 9588  GEYEFRVKAVNAAGVSKPSATV----------GPCDCQRPDMPP-SIDLKEFMEVEEGTN 9636

Query: 1572  YRVTTTPKNGPGPT----KTKTAGPDQTEMTIEGLQPTVEYV----VSVYAQNPSGESQP 1623
               +    K  P PT    K     PD  E  +         V      V  Q+   ++  
Sbjct: 9637  VNIVAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDTGL 9696

Query: 1624  LVQTAVTNIDR---------------PKG-LAFTDVDVDSIKIAWESPQ----GQVSRYR 1663
                TAV N+                 P G + F  V  D + ++W  P+     +++ Y 
Sbjct: 9697  YTITAVNNLGTASKEMRLNVLGRPGPPVGPIKFESVSADQMTLSWFPPKDDGGSKITNYV 9756

Query: 1664  VTY--SSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVA-----LHDDMESQPLIG 1716
             +    ++ +  +H    + + +E T  +  L  G EY   ++A     + + ++S+P   
Sbjct: 9757  IEKREANRKTWVHV---SSEPKECTYTIPKLLEGHEYVFRIMAQNKYGIGEPLDSEPETA 9813

Query: 1717  TQSTAIP-APTDLKFTQVTPTSLSAQWTPPNVQ----LTGYRVRVTPKEKTGPM-KEINL 1770
                 ++P AP     + VT  S++  W  P       +TGY + +  K+ T    K +N 
Sbjct: 9814  RNLFSVPGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPVTGYWLEM--KDTTSKRWKRVNR 9871

Query: 1771  APDSS-----SVVVSGLMVATKYEVSVYALKD------TLTSRPAQGVVTTLENVSPPRR 1819
              P  +     S  V+GL+  + Y+  VYA+        +L S PA    T  + ++PP  
Sbjct: 9872  DPIKAMTLGVSYKVTGLIEGSDYQFRVYAINAAGVGPASLPSDPA----TARDPIAPPGP 9927

Query: 1820  A--RVTDATETTITISWRTKTET----ITGFQVDAVPANGQTPIQRTIKPDVRS--YTIT 1871
                +VTD T+++  + W    +     +TG+ V+     G+   ++    +VR     +T
Sbjct: 9928  PFPKVTDWTKSSADLEWSPPLKDGGSKVTGYIVE-YKEEGKEEWEKGKDKEVRGTKLVVT 9986

Query: 1872  GLQPGTDYKIYLYTLNDNARSSPV----VIDASTAIDAPSNLRFLATTPNSLLVSWQPPR 1927
             GL+ G  YK  +  +N      P     VI+    + +P +L+  A+  + ++V      
Sbjct: 9987  GLKEGAFYKFRVRAVNIAGIGEPGEVTDVIEMKDRLVSP-DLQLDASVRDRIVVH-AGGV 10044

Query: 1928  ARITGYIIKYEKPGSPPREVV--PRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPL 1985
              RI  Y+      G PP  V      R    EATI      T      + +KN Q+S   
Sbjct: 10045 IRIIAYV-----SGKPPPTVTWNMNERTLPQEATIE-----TTAISSSMVIKNCQRSHQG 10094

Query: 1986  I----------GRKKTV----------QKTPFVTHPGYDTGNGIQL----PGTSGQQPSV 2021
             +           RKKT+            TPF+ H    T    +L    P   G  P +
Sbjct: 10095 VYSLLAKNEAGERKKTIIVDVLDVPGPVGTPFLAHNL--TNESCKLTWFSPEDDGGSP-I 10151

Query: 2022  GQQMIFEEHGFRRTTPPTTATPIRHRPRPYPPNVGQ----EALSQTTISWAPFQDTSEYI 2077
                +I +    RR   P T T  R          G+       ++ +I   PF +TSE +
Sbjct: 10152 TNYVIEKRESDRRAWTPVTYTVTRQNATVQGLIQGKAYFFRIAAENSIGMGPFVETSEAL 10211

Query: 2078  ISCHPVGTDEEPLQFRVPG-TSTSATLT 2104
             +   P+   E P    V   T  + TLT
Sbjct: 10212 VIREPITVPERPEDLEVKEVTKNTVTLT 10239



 Score = 77.0 bits (188), Expect = 2e-13
 Identities = 270/1352 (19%), Positives = 474/1352 (35%), Gaps = 184/1352 (13%)

Query: 679   GQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFS-PLVATSESVTEITASSFV 737
             G  + I+   H++   +  T  +   P  S TV+ +      P       V+EI   S  
Sbjct: 10774 GSKLEIRNAAHEDGGIYSLTVEN---PAGSKTVSVKVLVLDKPGPPRDLEVSEIRKDSCY 10830

Query: 738   VSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVN----IPDLLPGRKYIVNVYQI 793
             ++W    D        Y + E  D       P +ATS         L  G +Y+  V   
Sbjct: 10831 LTWKEPLDDGGSVITNYVV-ERRDVASAQWSPLSATSKKKSHFAKHLNEGNQYLFRVAAE 10889

Query: 794   SEDGEQSLILSTSQTTAPDA--PPDPTVD----QVDDTSIVVRWSRPQ----APITGYRI 843
             ++ G    + +     A D   PP P  D     VD T + + W++P     +PITGY +
Sbjct: 10890 NQYGRGPFVETPKPIKALDPLHPPGPPKDLHHVDVDKTEVSLVWNKPDRDGGSPITGYLV 10949

Query: 844   VYSPSVEGSSTELNLPETAN-SVTLSDLQPGVQYNITIYA---VEENQESTPVVIQQETT 899
              Y    EG+   +      N    ++ LQ G  Y   + A   V      T + I+ +  
Sbjct: 10950 EYQE--EGTQDWIKFKTVTNLECVVTGLQQGKTYRFRVKAENIVGLGLPDTTIPIECQEK 11007

Query: 900   GTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEH---GQRLPI 956
               P S  +    D++ +E   VK       P + + G  V        G      +   +
Sbjct: 11008 LVPPSVEL----DVKLIEGLVVKAGTTVRFP-AIIRGVPVPTAKWTTDGSEIKTDEHYTV 11062

Query: 957   SRNTFAEVTGLSPGV---TYYFKVFAVSHGRESKPLTAQQTTKLDAPTN----LQFVNET 1009
               + F+ V  +   +   T  +++  VS+   SK + A   T LD P      +  ++ T
Sbjct: 11063 ETDNFSSVLTIKNCLRRDTGEYQI-TVSNAAGSKTV-AVHLTVLDVPGPPTGPINILDVT 11120

Query: 1010  DSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVS 1065
                + + W PP+    + +  Y +    TR+      + G S +K  + +LQ   EY   
Sbjct: 11121 PEHMTISWQPPKDDGGSPVINYIVEKQDTRKDTWGVVSSGSSKTKLKIPHLQKGCEYVFR 11180

Query: 1066  LVAIKGNQESPKATGVFTTLQPGSSIP-----PYNTEVTETTIVITWT------PAPRIG 1114
             + A       P      T  +   S P     P  T++TE    ++WT       +P  G
Sbjct: 11181 VRAENKIGVGPPLDSTPTVAKHKFSPPSPPGKPVVTDITENAATVSWTLPKSDGGSPITG 11240

Query: 1115  FKLGVRPSQGGEAPREVTSDSG-SIVVSGLTPGVEYVYTIQVLR-DGQERDAPIVNKV-- 1170
             + +  R   G       T  +     V+GL  G  Y + +      G  + +P  + +  
Sbjct: 11241 YYMERREVTGKWVRVNKTPIADLKFRVTGLYEGNTYEFRVFAENLAGLSKPSPSSDPIKA 11300

Query: 1171  ---VTPLSPPTNLHLEANPDTGVLTVSWERSTTPD---ITGYRITTTPTNGQQGNSLEEV 1224
                + P  PP N  L+ +       + W +  +     I GY +        Q N + + 
Sbjct: 11301 CRPIKPPGPPINPKLK-DKSRETADLVWTKPLSDGGSPILGYVVECQKPGTAQWNRINKD 11359

Query: 1225  VHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVP--ISDTIIPAV---PPPTDLRFTNIG 1279
                 Q +     L  G EY   +       E  P  +++++I      PP  +L  T   
Sbjct: 11360 ELIRQCAFRVPGLIEGNEYRFRIKAANIVGEGEPRELAESVIAKDILHPPEVELDVTCRD 11419

Query: 1280  PDTMRVTWA----------PPPSIDLTN---FLVRYSPVKNEEDV--AELSISPSDNAVV 1324
               T+RV             P P I  T     LVR   V   +D+   EL I  +  A  
Sbjct: 11420 VITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRA-- 11477

Query: 1325  LTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSP---TGIDFSDITANSFTVHWIAP 1381
                     +Y++S  +     + + +       LD P     +  +++T  + T+ W  P
Sbjct: 11478 -----DHGKYIISAKNSSGHAQGSAI----VNVLDRPGPCQNLKVTNVTKENCTISWENP 11528

Query: 1382  R----ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNG---- 1433
                  + IT + + +   +  G          R  +   NL    EY   + A N     
Sbjct: 11529 LDNGGSEITNFIVEYRKPNQKGWSIVASDVTKR--LIKANLLANNEYYFRVCAENKVGVG 11586

Query: 1434  ---REESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYG---ETGG 1487
                  ++P+L          P +L +     T + + W  P        ++Y       G
Sbjct: 11587 PTIETKTPILAINPIDRPGEPENLHIADKGKTFVYLKWRRPDYDGGSPNLSYHVERRLKG 11646

Query: 1488  NSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASS--KPISINYRTEIDKP 1545
             +   +       K T  +  +   V+  I  + V  + +   S   K   +  + ++ KP
Sbjct: 11647 SDDWERVHKGSIKETHYM--VDRCVENQIYEFRVQTKNEGGESDWVKTEEVVVKEDLQKP 11704

Query: 1546  SQMQVTDVQDNSIS-VKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMT------ 1598
                    V D  +S V  + +   +   R+    +  P P    T   D T++T      
Sbjct: 11705 -------VLDLKLSGVLTVKAGDTI---RLEAGVRGKPFPEVAWTKDKDATDLTRSPRVK 11754

Query: 1599  IEGLQPTVEYVVSVYAQNPSGE--------SQPLVQTAVTNI-DRP---KGLAFTDVDVD 1646
             I+    + ++ ++   ++  G+        +   V  A  N+ D+P   + L   DV  D
Sbjct: 11755 IDTRADSSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATVNVLDKPGPVRNLKIVDVSSD 11814

Query: 1647  SIKIAWESPQG----QVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSV 1702
                + W+ P+     ++  Y +     +  +   + A      T   + L  G+EY   V
Sbjct: 11815 RCTVCWDPPEDDGGCEIQNYILEKCETKRMVWSTYSATVLTPGTTVTR-LIEGNEYIFRV 11873

Query: 1703  -----VALHDDMESQPLIGTQSTAIPA-PTDLKFTQVTPTSLSAQWTPPNVQ----LTGY 1752
                  +      ES+P+I       P  P   + T+V+   ++  W PP       +TGY
Sbjct: 11874 RAENKIGTGPPTESKPVIAKTKYDKPGRPDPPEVTKVSKEEMTVVWNPPEYDGGKSITGY 11933

Query: 1753  RVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKD------TLTSRPAQG 1806
              +    K  T  +     A     + V  L+   +Y+  V A  +      +L SRP   
Sbjct: 11934 FLEKKEKHSTRWVPVNKSAIPERRMKVQNLLPDHEYQFRVKAENEIGIGEPSLPSRPVVA 11993

Query: 1807  VVTTLENVSPPRRARVTDATETTITISWRTKT----ETITGFQV-------DAVPANGQT 1855
                 +E   PP   RV D T+ +IT+ W          I G+ V       DA P  G  
Sbjct: 11994 K-DPIEPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAPIIGYVVEMRPKIADASPDEGWK 12052

Query: 1856  PIQRTIKPDVRSYTITGLQPGTDYKIYLYTLN 1887
                   +   + +T+T L    +Y+  +   N
Sbjct: 12053 RCNAAAQLVRKEFTVTSLDENQEYEFRVCAQN 12084



 Score = 75.9 bits (185), Expect = 4e-13
 Identities = 162/749 (21%), Positives = 272/749 (36%), Gaps = 110/749 (14%)

Query: 1233  TFDNLSPGLEYNVSVYTVKDDKESVPIS-----DTIIPAVPPPTDLRF-------TNI-- 1278
             T ++L  G EY   V  V     S P +     D   P +PP  DL+        TN+  
Sbjct: 9580  TVEDLVEGGEYEFRVKAVNAAGVSKPSATVGPCDCQRPDMPPSIDLKEFMEVEEGTNVNI 9639

Query: 1279  -----GPDTMRVTW--APPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPG 1331
                  G     +TW  APP   D         PV  +  V +L +  +   V+  +    
Sbjct: 9640  VAKIKGVPFPTLTWFKAPPKKPD------NKEPVLYDTHVNKLVVDDTCTLVIPQSRRSD 9693

Query: 1332  TEY--VVSVSSVYEQHESTPLRGRQKTGLDSPTG-IDFSDITANSFTVHWIAPR----AT 1384
             T    + +V+++    +   L    + G   P G I F  ++A+  T+ W  P+    + 
Sbjct: 9694  TGLYTITAVNNLGTASKEMRLNVLGRPG--PPVGPIKFESVSADQMTLSWFPPKDDGGSK 9751

Query: 1385  ITGYRIRHHPE------HFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGR---- 1434
             IT Y I           H S  P+E        + T+  L  G EYV  I+A N      
Sbjct: 9752  ITNYVIEKREANRKTWVHVSSEPKEC-------TYTIPKLLEGHEYVFRIMAQNKYGIGE 9804

Query: 1435  --EESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVT----VRYYRITYGETGGN 1488
               +  P       +V   P    V + T  S+ ++W+ P       V  Y +   +T   
Sbjct: 9805  PLDSEPETARNLFSVPGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPVTGYWLEMKDTTSK 9864

Query: 1489  -------SPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPAS--SKPISINYR 1539
                     P++  T+  S     ++GL  G DY   VYA+   G  PAS  S P +    
Sbjct: 9865  RWKRVNRDPIKAMTLGVSYK---VTGLIEGSDYQFRVYAINAAGVGPASLPSDPATARDP 9921

Query: 1540  TEIDKPSQMQVTDVQDNSISVKWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQT 1595
                  P   +VTD   +S  ++W P      S VTGY V    +      K K      T
Sbjct: 9922  IAPPGPPFPKVTDWTKSSADLEWSPPLKDGGSKVTGYIVEYKEEGKEEWEKGKDKEVRGT 9981

Query: 1596  EMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVD-SIKIAWES 1654
             ++ + GL+    Y   V A N +G  +P   T V  I+    L   D+ +D S++     
Sbjct: 9982  KLVVTGLKEGAFYKFRVRAVNIAGIGEPGEVTDV--IEMKDRLVSPDLQLDASVRDRIVV 10039

Query: 1655  PQGQVSRY----------RVTYSSPEDGI-HELFPAPDGEEDTAELQGLRPGSEYTVSVV 1703
               G V R            VT++  E  +  E          +  ++  +   +   S++
Sbjct: 10040 HAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEATIETTAISSSMVIKNCQRSHQGVYSLL 10099

Query: 1704  ALHDDMESQPLIGTQSTAIPAPTDLKFT--QVTPTSLSAQWTPP----NVQLTGYRVRVT 1757
             A ++  E +  I      +P P    F    +T  S    W  P       +T Y +   
Sbjct: 10100 AKNEAGERKKTIIVDVLDVPGPVGTPFLAHNLTNESCKLTWFSPEDDGGSPITNYVIEKR 10159

Query: 1758  PKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRP---AQGVVTTLENV 1814
               ++      +       +  V GL+    Y   + A ++++   P       +   E +
Sbjct: 10160 ESDRRA-WTPVTYTVTRQNATVQGLIQGKAYFFRI-AAENSIGMGPFVETSEALVIREPI 10217

Query: 1815  SPPRR---ARVTDATETTITISWRTKT----ETITGFQVDAVPANGQTPIQRTIKPDV-- 1865
             + P R     V + T+ T+T++W          I  + +++    G     +    ++  
Sbjct: 10218 TVPERPEDLEVKEVTKNTVTLTWNPPKYDGGSEIINYVLES-RLIGTEKFHKVTNDNLLS 10276

Query: 1866  RSYTITGLQPGTDYKIYLYTLNDNARSSP 1894
             R YT+ GL+ G  Y+  +  +N   +  P
Sbjct: 10277 RKYTVKGLKEGDTYEYRVSAVNIVGQGKP 10305



 Score = 74.3 bits (181), Expect = 1e-12
 Identities = 171/843 (20%), Positives = 321/843 (38%), Gaps = 99/843 (11%)

Query: 1141  SGLTPGVEYVYTIQVLRDG----QERDAPIV---NKVVTPLSPPTNLHLEANPDTGVLTV 1193
             +GL  G EY Y +              +P++   + V  P SPP+   +  +  T  +T+
Sbjct: 19548 TGLREGCEYEYRVYAENAAGLSLPSETSPLIRAEDPVFLP-SPPSKPKIVDSGKT-TITI 19605

Query: 1194  SWERSTTPD---ITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTV 1250
             +W +        ITGY +    ++     +  + +   +   T   L+ G EY   V +V
Sbjct: 19606 AWVKPLFDGGAPITGYTVEYKKSDDTDWKTSIQSLRGTEY--TISGLTTGAEYVFRVKSV 19663

Query: 1251  KDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFL-VRYSPVKN-- 1307
                  S P SD+  P +    +          MR T         T  +  R  PV N  
Sbjct: 19664 NKVGASDP-SDSSDPQIAKEREEEPLFDIDSEMRKTLIVKAGASFTMTVPFRGRPVPNVL 19722

Query: 1308  ----EEDVAELS-ISPSDNAVVLT----NLLPGTEYVVSVSSVYEQHESTPLRGRQKTGL 1358
                 + D+   + +  +D+   LT    N     +Y +++ +V      T +     T  
Sbjct: 19723 WSKPDTDLRTRAYVDTTDSRTSLTIENANRNDSGKYTLTIQNVLSAASLTLVVKVLDTP- 19781

Query: 1359  DSPTGIDFSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRNSIT 1414
               PT I   D+T  S  + W  P     A +  Y I       + +     V ++ N ++
Sbjct: 19782 GPPTNITVQDVTKESAVLSWDVPENDGGAPVKNYHIEKRE---ASKKAWVSVTNNCNRLS 19838

Query: 1415  --LTNLTPGTEYVVSIVALNGREESPLLIGQQSTVS-------DVPRDLEVVAATPTSLL 1465
               +TNL  G  Y   +   +G  E  + I  ++            P  L V + +  S+ 
Sbjct: 19839 YKVTNLQEGAIYYFRV---SGENEFGVGIPAETKEGVKITEKPSPPEKLGVTSISKDSVS 19895

Query: 1466  ISWDAP----AVTVRYYRITYGETGGNSPVQEFTVPGSKSTA-TISGLKPGVDYTITVYA 1520
             ++W  P       + +Y +   E G  + V+      +KST   +SGL+   +Y   V+A
Sbjct: 19896 LTWLKPEHDGGSRIVHYVVEALEKGQKNWVK---CAVAKSTHHVVSGLRENSEYFFRVFA 19952

Query: 1521  VTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKW---LPSSSPVTGYRVTTT 1577
                 G S      + +  + +++ P ++ + +   +++ V+    L    P++G  +   
Sbjct: 19953 ENQAGLSDPRELLLPVLIKEQLEPP-EIDMKNFPSHTVYVRAGSNLKVDIPISGKPLPKV 20011

Query: 1578  PKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVS-------VYAQNPSGESQPLVQTAVT 1630
               +  G    K      TE+T E L   ++  V+       + A N SG ++  +   V 
Sbjct: 20012 TLSRDG-VPLKATMRFNTEITAENLTINLKESVTADAGRYEITAANSSGTTKAFINIVV- 20069

Query: 1631  NIDRPKG----LAFTDVDVDSIKIAWESPQ----GQVSRYRVTYSSPEDGIHELFPAPDG 1682
              +DRP      +  +D+  +S+ + WE P+     QV+ Y +        +     A   
Sbjct: 20070 -LDRPGPPTGPVVISDITEESVTLKWEPPKYDGGSQVTNYILLKRETSTAVWTEVSATVA 20128

Query: 1683  EEDTAELQGLRPGSEYTVSVVA-----LHDDMESQPLIGTQSTAIPAPTDLKF-TQVTPT 1736
                  ++  L  G EY   + A     + D ++S  +        P P    + T VT  
Sbjct: 20129 RT-MMKVMKLTTGEEYQFRIKAENRFGISDHIDSACVTVKLPYTTPGPPSTPWVTNVTRE 20187

Query: 1737  SLSAQWTPP----NVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSV 1792
             S++  W  P       + GY + +  +      K   L   ++   V+ +     YE  V
Sbjct: 20188 SITVGWHEPVSNGGSAVVGYHLEMKDRNSILWQKANKLVIRTTHFKVTTISAGLIYEFRV 20247

Query: 1793  YALKDTLTSRPAQGV--VTTLENVSPPRRARVTDATETTITISWRTKT----ETITGFQV 1846
             YA       +P+     V  ++   PPR  R+TD ++ ++++SW+         ITG+ V
Sbjct: 20248 YAENAAGVGKPSHPSEPVLAIDACEPPRNVRITDISKNSVSLSWQQPAFDGGSKITGYIV 20307

Query: 1847  DA--VPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLN--DNARSSPVVIDASTA 1902
             +   +P    T    T   + + + I+GL   + Y+  ++  N   +  +   V+   T 
Sbjct: 20308 ERRDLPDGRWTKASFTNVTETQ-FIISGLTQNSQYEFRVFARNAVGSISNPSEVVGPITC 20366

Query: 1903  IDA 1905
             ID+
Sbjct: 20367 IDS 20369



 Score = 65.5 bits (158), Expect = 6e-10
 Identities = 290/1521 (19%), Positives = 542/1521 (35%), Gaps = 205/1521 (13%)

Query: 628   IQWNAPQ---PSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISI 684
             + W+AP     S ++ + +  + +NS+   K  T P     Y   GL  G+ Y+ ++ + 
Sbjct: 21278 LTWDAPVYDGGSEVTGFHVEKKERNSILWQKVNTSPISGREYRATGLVEGLDYQFRVYAE 21337

Query: 685   QQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSAS 744
                G              S+P   +  T   +P  P    +    ++T  +  + W    
Sbjct: 21338 NSAG-------------LSSPSDPSKFTLAVSPVDP--PGTPDYIDVTRETITLKWNPPL 21382

Query: 745   DTVSGFRVEYELSEEGDEPQYLDLPSTATS---VNIPDLLPGRKYIVNVYQ------ISE 795
                    V Y + +     +++    T  S     +  L PG +Y   +        IS 
Sbjct: 21383 RDGGSKIVGYSIEKRQGNERWVRCNFTDVSECQYTVTGLSPGDRYEFRIIARNAVGTISP 21442

Query: 796   DGEQSLILSTSQTTAPDAPPDPTVD---QVDDTSIVVRWS--RPQAPITGYRIV----YS 846
               + S I+ T     P     P V+   +  D  I+      R +A + G  +     + 
Sbjct: 21443 PSQSSGIIMTRDENVP-----PIVEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVTWFK 21497

Query: 847   PSVE-GSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQES--TPVVIQQETTGTPR 903
               VE      + + +   S +L  ++   + +  +Y VE    S      I+ +   TP 
Sbjct: 21498 DGVEIEKRMNMEITDVLGSTSLF-VRDATRDHRGVYTVEAKNASGSAKAEIKVKVQDTPG 21556

Query: 904   SDTVPSPRDLQFVEVTDVKVTIMWTPPES----AVTGYRVDVIPVNLPGEHGQRLPISRN 959
                 P    ++F  +T  K+T+ W  P +     +T Y ++    +              
Sbjct: 21557 KVVGP----IRFTNITGEKMTLWWDAPLNDGCAPITHYIIEKRETSRLAWALIEDKCEAQ 21612

Query: 960   TFAEVTGLSPGVTYYFKVFAVSH---GR--ESKPLTAQ-QTTKLDAPTNLQFVNETDSTV 1013
             ++  +  L  G  Y F+V AV+    GR  +S P+ AQ Q T  DAP   +  N T +++
Sbjct: 21613 SYTAIK-LINGNEYQFRVSAVNKFGVGRPLDSDPVVAQIQYTVPDAPGIPEPSNITGNSI 21671

Query: 1014  LVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRN-------LQPASEYTVSL 1066
              + W  P +   G  +   +  R + +       +SK P+         L   +EY   +
Sbjct: 21672 TLTWARPESD-GGSEIQQYILERREKKSTRWVKVISKRPISETRFKVTGLTEGNEYEFHV 21730

Query: 1067  VAIKGNQESPKATGVFTTLQ-------PGSSIPPYNTEVTETTIVITWTPA------PRI 1113
             +A       P A+G+   ++       PG       T+ ++TT+ + W+          I
Sbjct: 21731 MAENAAGVGP-ASGISRLIKCREPVNPPGPPTVVKVTDTSKTTVSLEWSKPVFDGGMEII 21789

Query: 1114  GFKLGVRPSQGGEAPREVTSDS---GSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKV 1170
             G+ + +  +  G+   +V +++       V+ L  G EY + +  +    + D+  V   
Sbjct: 21790 GYIIEMCKADLGDW-HKVNAEACVKTRYTVTDLQAGEEYKFRVSAINGAGKGDSCEVTGT 21848

Query: 1171  VTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPT----NGQQGNSLEEVVH 1226
             +  +   T   L+ + +     V    ++      Y+   TPT          SL   +H
Sbjct: 21849 IKAVDRLTAPELDIDANFKQTHVVRAGASIRLFIAYQGRPTPTAVWSKPDSNLSLRADIH 21908

Query: 1227  ADQSSCTFD----NLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRFTNIGPDT 1282
                S  T      N +   +Y ++V      K S+  +  ++    PP  + F ++   +
Sbjct: 21909 TTDSFSTLTVENCNRNDAGKYTLTVENNSGSK-SITFTVKVLDTPGPPGPITFKDVTRGS 21967

Query: 1283  MRVTWAPPPSIDLTNFLVRYSPVKNEEDVAE---LSISPSDNAVVLTNLLPGTEYVVSVS 1339
               + W   P +D    +  Y   K E        +S   +     + +L  G  Y   VS
Sbjct: 21968 ATLMW-DAPLLDGGARIHHYVVEKREASRRSWQVISEKCTRQIFKVNDLAEGVPYYFRVS 22026

Query: 1340  SVYEQHESTPLRGRQKTGLDS----PTGIDFSDITANSFTVHWIAPR----ATITGYRIR 1391
             +V E     P    +          P  +D  D + +S  + W+ P     + ITGY + 
Sbjct: 22027 AVNEYGVGEPYEMPEPIVATEQPAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRITGYLLE 22086

Query: 1392  HHPEHFSGRPREDRVPHSRN-SITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDV 1450
                +   G        H++  + T+  L   TEY   + A N    S       S +   
Sbjct: 22087 MRQK---GSDFWVEAGHTKQLTFTVERLVEKTEYEFRVKAKNDAGYSEPREAFSSVIIKE 22143

Query: 1451  PR-----DLEVV--------AATPTSL---LISWDAPAVTVRYYRITYGETGGNSPVQEF 1494
             P+     DL  +        A +P ++   +    AP VT +   +   ET   S     
Sbjct: 22144 PQIEPTADLTGITNQLITCKAGSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVS----I 22199

Query: 1495  TVPGSKSTATISGLKPGVD--YTITVYAVTGRGDSPASSKPISINYRTEIDKPSQM---- 1548
             T    ++T T+     G    Y +T+       ++ A  K  S+     I +P  +    
Sbjct: 22200 TTTKDRTTLTVKDSMRGDSGRYFLTL-------ENTAGVKTFSVTV-VVIGRPGPVTGPI 22251

Query: 1549  QVTDVQDNSISVKWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQP 1604
             +V+ V   S  + W        + +T Y +    ++G    +   +   +T++ +  L  
Sbjct: 22252 EVSSVSAESCVLSWGEPKDGGGTEITNY-IVEKRESGTTAWQLVNSSVKRTQIKVTHLTK 22310

Query: 1605  TVEYVVSVYAQNPSGESQPLVQTAV------TNIDRPKGLAFTDVDVDSIKIAWESPQGQ 1658
              +EY   V ++N  G S+PL    +           P       V  +++ I WE P   
Sbjct: 22311 YMEYSFRVSSENRFGVSKPLESAPIIAEHPFVPPSAPTRPEVYHVSANAMSIRWEEPYHD 22370

Query: 1659  VSRYRVTYSSPEDGIHELFPAPDGE----EDTAELQGLRPGSEYTVSVVALH------DD 1708
                  + Y   +   + +    + +    E   ++ GL  G EY     AL+        
Sbjct: 22371 GGSKIIGYWVEKKERNTILWVKENKVPCLECNYKVTGLVEGLEYQFRTYALNAAGVSKAS 22430

Query: 1709  MESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPP----NVQLTGYRVRVTPKEKTGP 1764
               S+P++      + AP   + T VT +++S  W+ P      ++ GY +   P  + G 
Sbjct: 22431 EASRPIMA--QNPVDAPGRPEVTDVTRSTVSLIWSAPAYDGGSKVVGYIIERKPVSEVGD 22488

Query: 1765  ---MKEINLAPDSSSVVVSGLMVATKYEVSVYALKDT-LTSRPAQ--GVVTTLENVSPPR 1818
                +K        +   V+ L     YE  V A     + S+ ++  G VT  +  +PP+
Sbjct: 22489 GRWLKCNYTIVSDNFFTVTALSEGDTYEFRVLAKNAAGVISKGSESTGPVTCRDEYAPPK 22548

Query: 1819  RARVTDATETTITISWRTKTETITGFQVDAVP------ANGQTPIQRTIKPDV-----RS 1867
                  DA      ++ R  ++ +    V   P        G   +    K  +     R+
Sbjct: 22549 AE--LDARLHGDLVTIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRA 22606

Query: 1868  YTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAP---SNLRFLATTPNSLLVSWQ 1924
               +      +D   Y  T+  NA  +  V      +D+P     L     T     ++W 
Sbjct: 22607 TAVIKFCDRSDSGKYTLTVK-NASGTKAVSVMVKVLDSPGPCGKLTVSRVTQEKCTLAWS 22665

Query: 1925  PPR----ARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKN-- 1978
              P+    A IT YI++  +       +V    P ++   +T L    EY   V A+    
Sbjct: 22666 LPQEDGGAEITHYIVERRETSRLNWVIVEGECPTLS-YVVTRLIKNNEYIFRVRAVNKYG 22724

Query: 1979  ---NQKSEPLIGRKKTVQKTP 1996
                  +SEP++ R      +P
Sbjct: 22725 PGVPVESEPIVARNSFTIPSP 22745



 Score = 64.3 bits (155), Expect = 1e-09
 Identities = 115/519 (22%), Positives = 183/519 (35%), Gaps = 81/519 (15%)

Query: 1542  IDKPS---QMQVTDVQDNSISVKWLPSSSP----VTGYRVTTTP-KNGPGPTKTKTAGPD 1593
             +DKP     +++ DV  +  +V W P        +  Y +     K     T + T    
Sbjct: 11797 LDKPGPVRNLKIVDVSSDRCTVCWDPPEDDGGCEIQNYILEKCETKRMVWSTYSATVLTP 11856

Query: 1594  QTEMT--IEGLQPTVEYVVSVYAQN-----PSGESQPLV-QTAVTNIDRPKGLAFTDVDV 1645
              T +T  IEG     EY+  V A+N     P  ES+P++ +T      RP     T V  
Sbjct: 11857 GTTVTRLIEGN----EYIFRVRAENKIGTGPPTESKPVIAKTKYDKPGRPDPPEVTKVSK 11912

Query: 1646  DSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGE----EDTAELQGLRPGSEYTVS 1701
             + + + W  P+    +    Y   +   H     P  +    E   ++Q L P  EY   
Sbjct: 11913 EEMTVVWNPPEYDGGKSITGYFLEKKEKHSTRWVPVNKSAIPERRMKVQNLLPDHEYQFR 11972

Query: 1702  VVALHD------DMESQPLIGTQSTAIPAP-TDLKFTQVTPTSLSAQWTPP----NVQLT 1750
             V A ++       + S+P++       P P T+ +    T  S++  W  P       + 
Sbjct: 11973 VKAENEIGIGEPSLPSRPVVAKDPIEPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAPII 12032

Query: 1751  GYRVRVTPKEKTGP----MKEINLAPD--SSSVVVSGLMVATKYEVSVYALKDTLTSRPA 1804
             GY V + PK          K  N A         V+ L    +YE  V A       RPA
Sbjct: 12033 GYVVEMRPKIADASPDEGWKRCNAAAQLVRKEFTVTSLDENQEYEFRVCAQNQVGIGRPA 12092

Query: 1805  Q--GVVTTLENVSPPRRARVTDATETTIT-------------------ISWRTK--TETI 1841
             +    +   E + PP         +  I                    ++WR       +
Sbjct: 12093 ELKEAIKPKEILEPPEIDLDASMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVV 12152

Query: 1842  TGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDAST 1901
                QVD V       I  + + D   Y++T + P  +  +++     N R    V+D   
Sbjct: 12153 RKGQVDLVDTMAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFV-----NVR----VLDTPG 12203

Query: 1902  AIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREVVPRPRPGVTE 1957
              +   S+L+    T  S  VSW PP     +++T YI++  +        V  P    T 
Sbjct: 12204 PV---SDLKVSDVTKTSCHVSWAPPENDGGSQVTHYIVEKREADRKTWSTVT-PEVKKTS 12259

Query: 1958  ATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQKTP 1996
               +T L PG EY   V A+       P    K  +   P
Sbjct: 12260 FHVTNLVPGNEYYFRVTAVNEYGPGVPTDVPKPVLASDP 12298



 Score = 62.4 bits (150), Expect = 5e-09
 Identities = 182/847 (21%), Positives = 298/847 (35%), Gaps = 156/847 (18%)

Query: 1263 IIPAVPPPTDLRFTNIGPDTMRVTWAPPPS---IDLTNFLVRYSPVKNEEDVAELSISPS 1319
            +I    P  +L  T      + + W  P +     +  ++V    +K +  V     + S
Sbjct: 6589 VIDVPGPVRNLEVTETFDGEVSLAWEEPLTDGGSKIIGYVVERRDIKRKTWVLATDRAES 6648

Query: 1320 DNAVVLTNLLPGTEYVVSVSS-----VYEQHES-TPLRGRQKTGLDSPT-GIDFSDITAN 1372
                V      G EY+  VS+       E  E+  P+  R K  +  P   +  +D+   
Sbjct: 6649 CEFTVTGLQKGGVEYLFRVSARNRVGTGEPVETDNPVEARSKYDVPGPPLNVTITDVNRF 6708

Query: 1373 SFTVHWIAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSI 1428
              ++ W  P     A IT Y I    +          V     S T+T++  G EY   +
Sbjct: 6709 GVSLTWEPPEYDGGAEITNYVIELRDKTSIRWDTAMTVRAEDLSATVTDVVEGQEYSFRV 6768

Query: 1429 VALNGREESPLLIGQQSTVSDV------------PRDLEVVAATPTSLLISWDAP----A 1472
                 R ++ + +G+ S  +              P +L     T +S+ + W+ P     
Sbjct: 6769 -----RAQNRIGVGKPSAATPFVKVADPIERPSPPVNLTSSDQTQSSVQLKWEPPLKDGG 6823

Query: 1473 VTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSK 1532
              +  Y I   E G ++ ++       + T  ++GL+ G  Y   V A    G S  S  
Sbjct: 6824 SPILGYIIERCEEGKDNWIRCNMKLVPELTYKVTGLEKGNKYLYRVSAENKAGVSDPSEI 6883

Query: 1533 PISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSS--PVTGYRVTTTPKNGPGPTKTKTA 1590
               +       +P+ M ++  +D    +   P +   P TGY         P PT T   
Sbjct: 6884 LGPLTADDAFVEPT-MDLSAFKDGLEVIVPNPITILVPSTGY---------PRPTATWCF 6933

Query: 1591 GPDQTE----MTIEGLQPTVEYVVSVYAQNPSG----ESQPLVQTAVTNID--------R 1634
            G    E    + ++ L    E V+S   ++  G    + +  V+T    ID         
Sbjct: 6934 GDKVLETGDRVKMKTLSAYAELVISPSERSDKGIYTLKLENRVKTISGEIDVNVIARPSA 6993

Query: 1635 PKGLAFTDVDVDSIKIAWESPQ----GQVSRY--------RVTYSSPEDGIHEL-FPAPD 1681
            PK L F D+  DS+ + WE P       ++ Y        R T++   D + +L F  PD
Sbjct: 6994 PKELKFGDITKDSVHLTWEPPDDDGGSPLTGYVVEKREVSRKTWTKVMDFVTDLEFTVPD 7053

Query: 1682 GEEDTAELQGLRPGSEYTVSVVALHDDMESQPL-------IGTQSTAIPAPTDLKFTQVT 1734
                      L  G EY   V A +     +P        + T +T    P ++K+   T
Sbjct: 7054 ----------LVQGKEYLFKVCARNKCGPGEPAYVDEPVNMSTPATVPDPPENVKWRDRT 7103

Query: 1735 PTSLSAQWTPP----NVQLTGYRVRVTPKEKTGPMKEINLAPD--SSSVVVSGLMVATKY 1788
              S+   W PP      ++ GY V   P+   G  K +        + + V+GL     Y
Sbjct: 7104 ANSIFLTWDPPKNDGGSRIKGYIVERCPR---GSDKWVACGEPVAETKMEVTGLEEGKWY 7160

Query: 1789 EVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETT-----------ITISWRTK 1837
               V AL     S+P++          P    +  D  E             +T+   TK
Sbjct: 7161 AYRVKALNRQGASKPSR----------PTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTK 7210

Query: 1838 TE---TITGFQVDAVPANGQTPIQRTIKPDVR----------SYTITGLQPGTDYKIYLY 1884
             E   T+TG      P    T     +K D R          + TI   +        + 
Sbjct: 7211 IELPATVTG---KPEPKITWTKADMILKQDKRITIENVPKKSTVTIVDSKRSDTGTYIIE 7267

Query: 1885 TLNDNARSSPVV-IDASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEK 1939
             +N   R++ VV ++       P+       T  S L++W PPR    ++IT Y+++   
Sbjct: 7268 AVNVCGRATAVVEVNVLDKPGPPAAFDITDVTNESCLLTWNPPRDDGGSKITNYVVERRA 7327

Query: 1940 PGSPPREVVPRPRPGV--TEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQKTPF 1997
              S   EV  +    V  T    T L P  EY   V A       E + G  + VQ +P 
Sbjct: 7328 TDS---EVWHKLSSTVKDTNFKATKLIPNKEYIFRVAA-------ENMYGVGEPVQASPI 7377

Query: 1998 VTHPGYD 2004
                 +D
Sbjct: 7378 TAKYQFD 7384



 Score = 52.8 bits (125), Expect = 4e-06
 Identities = 80/336 (23%), Positives = 120/336 (35%), Gaps = 46/336 (13%)

Query: 602  LQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQP---SHISKYILRWRPKN-SVGRWKEA 657
            ++ Y   S P  + +T+  ++  S  + W+AP     S I+ Y++  R  +     W+E 
Sbjct: 8995 VEVYDRPSPPRNLAVTDIKAE--SCYLTWDAPLDNGGSEITHYVIDKRDASRKKAEWEEV 9052

Query: 658  TIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTP 717
            T       Y I  L P   YE ++ ++ +YG  +  + D         V  +       P
Sbjct: 9053 TNTAVEKRYGIWKLIPNGQYEFRVRAVNKYGISDECKSD-------KVVIQDPYRLPGPP 9105

Query: 718  FSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTA----- 772
              P V         T  S +VSW    D        Y L +  +   Y    S A     
Sbjct: 9106 GKPKVLAR------TKGSMLVSWTPPLDNGGSPITGYWLEKREEGSPYWSRVSRAPITKV 9159

Query: 773  ----TSVNIPDLLPGRKY-----IVNVYQISEDGEQSLILSTSQTTAPDAPPD-PTVDQV 822
                   N+P LL G KY      +N   I    E S          P  PP  P V   
Sbjct: 9160 GLKGVEFNVPRLLEGVKYQFRAMAINAAGIGPPSEPSDPEVAGDPIFPPGPPSCPEVKDK 9219

Query: 823  DDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPE---TANSVTLSDLQPGVQ 875
              +SI + W  P     +PI GY +            +N P+   T     + +L+   +
Sbjct: 9220 TKSSISLGWKPPAKDGGSPIKGYIVEMQEEGTTDWKRVNEPDKLITTCECVVPNLKELRK 9279

Query: 876  YNITIYAVEENQESTPVVIQQETTG-TPRSDTVPSP 910
            Y   + AV E  ES P     +TTG  P +D    P
Sbjct: 9280 YRFRVKAVNEAGESEP----SDTTGEIPATDIQEEP 9311



 Score = 43.9 bits (102), Expect = 0.002
 Identities = 50/204 (24%), Positives = 83/204 (40%), Gaps = 22/204 (10%)

Query: 717   PFSPLVATSESVTEITASSFVVSWVSASDT----VSGFRVEYELSEEGDEPQYLDLPSTA 772
             P  P+V     +  +  +S V+SW   +D     ++ + VE   ++EG E Q +    + 
Sbjct: 24229 PTGPIV-----IEALLKNSAVISWKPPADDGGSWITNYVVEKCEAKEGAEWQLVSSAISV 24283

Query: 773   TSVNIPDLLPGRKYIV-----NVYQISEDGE-QSLILSTSQTTAPDAPPDPTVDQVDDTS 826
             T+  I +L     Y       N + IS+  E  S+++  S    P AP  PT+  V   S
Sbjct: 24284 TTCRIVNLTENAGYYFRVSAQNTFGISDPLEVSSVVIIKSPFEKPGAPGKPTITAVTKDS 24343

Query: 827   IVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSV-TLSDLQPGVQYNITIY 881
              VV W  P     A I  Y +      +     +   E   +V ++ +L  G++Y   + 
Sbjct: 24344 CVVAWKPPASDGGAKIRNYYLEKREKKQNKWISVTTEEIRETVFSVKNLIEGLEYEFRVK 24403

Query: 882   AVEENQESTPVVIQQETTGTPRSD 905
                   ES    I +    TP+SD
Sbjct: 24404 CENLGGESEWSEISEPI--TPKSD 24425



 Score = 41.2 bits (95), Expect = 0.012
 Identities = 92/413 (22%), Positives = 157/413 (38%), Gaps = 51/413 (12%)

Query: 1285  VTWAPPPSID---LTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSV 1341
             ++W PP       +TN++V     K   +   +S + S     + NL     Y   VS+ 
Sbjct: 24245 ISWKPPADDGGSWITNYVVEKCEAKEGAEWQLVSSAISVTTCRIVNLTENAGYYFRVSAQ 24304

Query: 1342  YEQHESTPLRGRQKTGLDSPTGID-------FSDITANSFTVHWIAPRATITGYRIRHHP 1394
                  S PL       + SP            + +T +S  V W  P A+  G +IR++ 
Sbjct: 24305 NTFGISDPLEVSSVVIIKSPFEKPGAPGKPTITAVTKDSCVVAW-KPPASDGGAKIRNYY 24363

Query: 1395  EHFSGRPREDRVPHSRNSITLT-----NLTPGTEYVVSIVA--LNGREESPLLIGQQSTV 1447
                  + +   +  +   I  T     NL  G EY   +    L G  E   +    +  
Sbjct: 24364 LEKREKKQNKWISVTTEEIRETVFSVKNLIEGLEYEFRVKCENLGGESEWSEISEPITPK 24423

Query: 1448  SDVP----------RDLEVVAATPTSLLISWDA-PAVTVRYYRITYGET----GGNSPVQ 1492
             SDVP          R+L V   +  +L+      P   V++YR   G+     G    +Q
Sbjct: 24424 SDVPIQAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYR--QGKEIIADGLKYRIQ 24481

Query: 1493  EFTVPGSKSTATISGLKPGVDYTITVYAV--TGRGDSPASSKPISINYRTEIDKPSQMQ- 1549
             EF   G      I+ +    D   TVY V  T +G S + +  + +    +I  P  ++ 
Sbjct: 24482 EFK--GGYHQLIIASV---TDDDATVYQVRATNQGGSVSGTASLEVEVPAKIHLPKTLEG 24536

Query: 1550  ---VTDVQDNSISVKWLPSSS---PVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQ 1603
                V  ++   +S+K +P S    PV  ++      +  G  +        + +   G++
Sbjct: 24537 MGAVHALRGEVVSIK-IPFSGKPDPVITWQKGQDLIDNNGHYQVIVTRSFTSLVFPNGVE 24595

Query: 1604  PTVEYVVSVYAQNPSGESQPLVQTAVTNI-DRPKGLAFTDVDVDSIKIAWESP 1655
                     V A+N  G  Q  V+  V ++ D P+G+  +DV  DS+ + W  P
Sbjct: 24596 RKDAGFYVVCAKNRFGIDQKTVELDVADVPDPPRGVKVSDVSRDSVNLTWTEP 24648



 Score = 37.7 bits (86), Expect = 0.13
 Identities = 36/131 (27%), Positives = 53/131 (40%), Gaps = 8/131 (6%)

Query: 894   IQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPVNLPGE 949
             I Q+T     +D    PR ++  +V+   V + WT P     S +T Y V+        E
Sbjct: 24612 IDQKTVELDVADVPDPPRGVKVSDVSRDSVNLTWTEPASDGGSKITNYIVEKCATT--AE 24669

Query: 950   HGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQ--TTKLDAPTNLQFVN 1007
                R+  +R T   V  L    +Y F+V A +    SKP    +   TK D    + +  
Sbjct: 24670 RWLRVGQARETRYTVINLFGKTSYQFRVIAENKFGLSKPSEPSEPTITKEDKTRAMNYDE 24729

Query: 1008  ETDSTVLVRWT 1018
             E D T  V  T
Sbjct: 24730 EVDETREVSMT 24740



 Score = 35.0 bits (79), Expect = 0.86
 Identities = 38/169 (22%), Positives = 71/169 (42%), Gaps = 17/169 (10%)

Query: 1519  YAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWL-PSS---SPVTGYRV 1574
             Y V  +       K + ++     D P  ++V+DV  +S+++ W  P+S   S +T Y V
Sbjct: 24602 YVVCAKNRFGIDQKTVELDVADVPDPPRGVKVSDVSRDSVNLTWTEPASDGGSKITNYIV 24661

Query: 1575  TTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPL--VQTAVTNI 1632
                        +   A   +T  T+  L     Y   V A+N  G S+P    +  +T  
Sbjct: 24662 EKCATTAERWLRVGQA--RETRYTVINLFGKTSYQFRVIAENKFGLSKPSEPSEPTITKE 24719

Query: 1633  DRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPD 1681
             D+ + + + D +VD  +        +VS  + ++SS ++   +   A D
Sbjct: 24720 DKTRAMNY-DEEVDETR--------EVSMTKASHSSTKELYEKYMIAED 24759


>gi|109633039 protein tyrosine phosphatase, receptor type, F isoform 2
            precursor [Homo sapiens]
          Length = 1898

 Score =  153 bits (387), Expect = 2e-36
 Identities = 172/631 (27%), Positives = 264/631 (41%), Gaps = 71/631 (11%)

Query: 1402 REDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPR---DLEVVA 1458
            +ED +P  RN + L+N+     Y    ++  G  E+      Q TV  +P+   DL V  
Sbjct: 274  KEDEMPVGRNVLELSNVVRSANYTCVAISSLGMIEATA----QVTVKALPKPPIDLVVTE 329

Query: 1459 ATPTSLLISWDAP-AVTVRYYRITYGETGGNSPVQEFTVPGSKSTA-TISGLKPGVDYTI 1516
             T TS+ ++WD+  +  V YY I Y   G   P QE  V G  +T  +I GL P  +Y  
Sbjct: 330  TTATSVTLTWDSGNSEPVTYYGIQYRAAGTEGPFQE--VDGVATTRYSIGGLSPFSEYAF 387

Query: 1517 TVYAVTGRGDSPASSKPISINYRTEIDKPS----QMQVTDVQDNSISVKWLPSSSP---V 1569
             V AV   G  P S    ++  RT    PS    ++Q   +  +++ V+W P   P   V
Sbjct: 388  RVLAVNSIGRGPPSE---AVRARTGEQAPSSPPRRVQARMLSASTMLVQWEPPEEPNGLV 444

Query: 1570 TGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEG-LQPTVEYVVSVYAQNPSGESQPLVQTA 1628
             GYRV  TP +   P        D   +T  G L P + Y + V A    G+  P     
Sbjct: 445  RGYRVYYTPDSRRPPNAWHKHNTDAGLLTTVGSLLPGITYSLRVLAFTAVGDGPPSPTIQ 504

Query: 1629 V-TNIDRPKGLAFTDVDVDS---IKIAWE-SPQGQVSRYRVTY--SSPEDGIHELFPAPD 1681
            V T    P   A    +V+S   I+++W   PQ ++  Y + Y  +  ED  H++   P 
Sbjct: 505  VKTQQGVPAQPADFQAEVESDTRIQLSWLLPPQERIIMYELVYWAAEDEDQQHKVTFDPT 564

Query: 1682 GEEDTAELQGLRPGSEYTVSVVALHD--------DMESQPLIGTQSTAIPAPTDLKFTQV 1733
                +  L+ L+P + Y   + A  D         +E++     QST    P  +    +
Sbjct: 565  S---SYTLEDLKPDTLYRFQLAARSDMGVGVFTPTIEART---AQSTPSAPPQKVMCVSM 618

Query: 1734 TPTSLSAQWTPP-----NVQLTGYRV--RVTPKEKTGPMKEINLAPDSSSVVVSGLMVAT 1786
              T++   W PP     N  +T Y V       E  G      ++ + SS  + GL   T
Sbjct: 619  GSTTVRVSWVPPPADSRNGVITQYSVAYEAVDGEDRGRHVVDGISREHSSWDLVGLEKWT 678

Query: 1787 KYEVSVYALKDTLTSRPAQGV-VTTLENV--SPPRRARVTDATETTITISWRTKTET--- 1840
            +Y V V A  D      +  V V T E+V   PPR+  V     T + + W+    +   
Sbjct: 679  EYRVWVRAHTDVGPGPESSPVLVRTDEDVPSGPPRKVEVEPLNSTAVHVYWKLPVPSKQH 738

Query: 1841 --ITGFQVDAVPANGQTP-----IQRTIKPDVRSYTITGLQPGTDYKIYLY---TLNDNA 1890
              I G+QV  V      P     IQ  +  + +  TI+GL P T Y + +    T  D A
Sbjct: 739  GQIRGYQVTYVRLENGEPRGLPIIQDVMLAEAQETTISGLTPETTYSVTVAAYTTKGDGA 798

Query: 1891 RSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPR---ARITGYIIKYEKPGSPPREV 1947
            RS P ++  + A+     +    T  N+ L+ W PP+     + GY ++Y +        
Sbjct: 799  RSKPKIVTTTGAVPGRPTMMISTTAMNTALLQWHPPKELPGELLGYRLQYCRADEARPNT 858

Query: 1948 VPRPRPGVTEATITGLEPGTEYTIYVIALKN 1978
            +   +      T+TGL  GT Y I+ +A KN
Sbjct: 859  IDFGKDD-QHFTVTGLHKGTTY-IFRLAAKN 887



 Score =  142 bits (357), Expect = 5e-33
 Identities = 167/722 (23%), Positives = 287/722 (39%), Gaps = 69/722 (9%)

Query: 1264 IPAVP-PPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNA 1322
            + A+P PP DL  T     ++ +TW    S  +T + ++Y     E    E+    +   
Sbjct: 315  VKALPKPPIDLVVTETTATSVTLTWDSGNSEPVTYYGIQYRAAGTEGPFQEVD-GVATTR 373

Query: 1323 VVLTNLLPGTEYVVSVSSVYEQHESTPLRG-RQKTGLDSPTG----IDFSDITANSFTVH 1377
              +  L P +EY   V +V       P    R +TG  +P+     +    ++A++  V 
Sbjct: 374  YSIGGLSPFSEYAFRVLAVNSIGRGPPSEAVRARTGEQAPSSPPRRVQARMLSASTMLVQ 433

Query: 1378 WIAPR---ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLT---NLTPGTEYVVSIVAL 1431
            W  P      + GYR+ + P+  S RP      H+ ++  LT   +L PG  Y + ++A 
Sbjct: 434  WEPPEEPNGLVRGYRVYYTPD--SRRPPNAWHKHNTDAGLLTTVGSLLPGITYSLRVLAF 491

Query: 1432 NGREESP----LLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVT-VRYYRITYGETG 1486
                + P    + +  Q  V   P D +    + T + +SW  P    +  Y + Y    
Sbjct: 492  TAVGDGPPSPTIQVKTQQGVPAQPADFQAEVESDTRIQLSWLLPPQERIIMYELVYWAAE 551

Query: 1487 GNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPS 1546
                  + T   + S+ T+  LKP   Y    + +  R D        +I  RT    PS
Sbjct: 552  DEDQQHKVTFDPT-SSYTLEDLKPDTLYR---FQLAARSDMGVGVFTPTIEARTAQSTPS 607

Query: 1547 ----QMQVTDVQDNSISVKWLPSSSP-----VTGYRVTTTPKNGPGPTKTKTAG--PDQT 1595
                ++    +   ++ V W+P  +      +T Y V     +G    +    G   + +
Sbjct: 608  APPQKVMCVSMGSTTVRVSWVPPPADSRNGVITQYSVAYEAVDGEDRGRHVVDGISREHS 667

Query: 1596 EMTIEGLQPTVEYVVSVYAQN---PSGESQPLVQTAVTNIDR--PKGLAFTDVDVDSIKI 1650
               + GL+   EY V V A     P  ES P++     ++    P+ +    ++  ++ +
Sbjct: 668  SWDLVGLEKWTEYRVWVRAHTDVGPGPESSPVLVRTDEDVPSGPPRKVEVEPLNSTAVHV 727

Query: 1651 AWESP-----QGQVSRYRVTYSSPEDGIHELFPAPD----GEEDTAELQGLRPGSEYTVS 1701
             W+ P      GQ+  Y+VTY   E+G     P        E     + GL P + Y+V+
Sbjct: 728  YWKLPVPSKQHGQIRGYQVTYVRLENGEPRGLPIIQDVMLAEAQETTISGLTPETTYSVT 787

Query: 1702 VVALH---DDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNV---QLTGYRVR 1755
            V A     D   S+P I T + A+P    +  +     +   QW PP     +L GYR++
Sbjct: 788  VAAYTTKGDGARSKPKIVTTTGAVPGRPTMMISTTAMNTALLQWHPPKELPGELLGYRLQ 847

Query: 1756 VTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVS 1815
                ++  P   I+   D     V+GL   T Y   + A          +  + T E++ 
Sbjct: 848  YCRADEARP-NTIDFGKDDQHFTVTGLHKGTTYIFRLAAKNRAGLGEEFEKEIRTPEDLP 906

Query: 1816 P--PRRARVTDATETTITISW-----RTKTETITGFQVDAVPANGQTPIQRTIKPDVRSY 1868
               P+   VT  T +T  ++W       +   I  + V     N Q  +Q  I  D R +
Sbjct: 907  SGFPQNLHVTGLTTSTTELAWDPPVLAERNGRIISYTVVFRDINSQQELQN-ITTDTR-F 964

Query: 1869 TITGLQPGTDY--KIYLYTLNDNARSSPVVIDASTAIDA--PSNLRFLATTPNSLLVSWQ 1924
            T+TGL+P T Y  K+  +T   +   SP +   +  ++     N R  A    S+L+SW+
Sbjct: 965  TLTGLKPDTTYDIKVRAWTSKGSGPLSPSIQSRTMPVEQVFAKNFRVAAAMKTSVLLSWE 1024

Query: 1925 PP 1926
             P
Sbjct: 1025 VP 1026



 Score =  134 bits (338), Expect = 8e-31
 Identities = 178/753 (23%), Positives = 299/753 (39%), Gaps = 71/753 (9%)

Query: 1053 LRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPA-- 1110
            L N+  ++ YT   ++  G  E+     V    +P   I    TE T T++ +TW     
Sbjct: 287  LSNVVRSANYTCVAISSLGMIEATAQVTVKALPKP--PIDLVVTETTATSVTLTWDSGNS 344

Query: 1111 -PRIGFKLGVRPSQGGEAPREVTSDSGSI--VVSGLTPGVEYVYTIQVLRD-GQERDAPI 1166
             P   + +  R + G E P +      +    + GL+P  EY + +  +   G+   +  
Sbjct: 345  EPVTYYGIQYRAA-GTEGPFQEVDGVATTRYSIGGLSPFSEYAFRVLAVNSIGRGPPSEA 403

Query: 1167 VNKVV---TPLSPPTNLHLEANPDTGVLTVSWERSTTPD--ITGYRITTTPTNGQQGNSL 1221
            V        P SPP  +       + +L V WE    P+  + GYR+  TP + +  N+ 
Sbjct: 404  VRARTGEQAPSSPPRRVQARMLSASTML-VQWEPPEEPNGLVRGYRVYYTPDSRRPPNAW 462

Query: 1222 EEVVHADQSSCTFDNLSPGLEYNVSVYT---VKDDKESVPISDTIIPAVPP-PTDLRFTN 1277
             +         T  +L PG+ Y++ V     V D   S  I       VP  P D +   
Sbjct: 463  HKHNTDAGLLTTVGSLLPGITYSLRVLAFTAVGDGPPSPTIQVKTQQGVPAQPADFQAEV 522

Query: 1278 IGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVS 1337
                 ++++W  PP   +  + + Y   ++E+   +++  P+ ++  L +L P T Y   
Sbjct: 523  ESDTRIQLSWLLPPQERIIMYELVYWAAEDEDQQHKVTFDPT-SSYTLEDLKPDTLYRFQ 581

Query: 1338 VSSVYEQHES--TPL---RGRQKTGLDSPTGIDFSDITANSFTVHWIAPRA-----TITG 1387
            +++  +      TP    R  Q T    P  +    + + +  V W+ P A      IT 
Sbjct: 582  LAARSDMGVGVFTPTIEARTAQSTPSAPPQKVMCVSMGSTTVRVSWVPPPADSRNGVITQ 641

Query: 1388 YRIRHHPEHFSGRPRE--DRVPHSRNSITLTNLTPGTEYVVSIVALN----GREESPLLI 1441
            Y + +       R R   D +    +S  L  L   TEY V + A      G E SP+L+
Sbjct: 642  YSVAYEAVDGEDRGRHVVDGISREHSSWDLVGLEKWTEYRVWVRAHTDVGPGPESSPVLV 701

Query: 1442 GQQSTV-SDVPRDLEVVAATPTSLLISWDAPAVT-----VRYYRITY-----GETGGNSP 1490
                 V S  PR +EV     T++ + W  P  +     +R Y++TY     GE  G   
Sbjct: 702  RTDEDVPSGPPRKVEVEPLNSTAVHVYWKLPVPSKQHGQIRGYQVTYVRLENGEPRGLPI 761

Query: 1491 VQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQV 1550
            +Q+  +  ++ T TISGL P   Y++TV A T +GD  A SKP  +     +     M +
Sbjct: 762  IQDVMLAEAQET-TISGLTPETTYSVTVAAYTTKGDG-ARSKPKIVTTTGAVPGRPTMMI 819

Query: 1551 TDVQDNSISVKWLPSS---SPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVE 1607
            +    N+  ++W P       + GYR+     +   P  T   G D    T+ GL     
Sbjct: 820  STTAMNTALLQWHPPKELPGELLGYRLQYCRADEARP-NTIDFGKDDQHFTVTGLHKGTT 878

Query: 1608 YVVSVYAQNPSGESQPLVQTAVTNIDRPKG----LAFTDVDVDSIKIAWESP-----QGQ 1658
            Y+  + A+N +G  +   +   T  D P G    L  T +   + ++AW+ P      G+
Sbjct: 879  YIFRLAAKNRAGLGEEFEKEIRTPEDLPSGFPQNLHVTGLTTSTTELAWDPPVLAERNGR 938

Query: 1659 VSRYRVTYSSPEDGIHELFPAPDGEEDTA-ELQGLRPGSEYTVSVVALHDDMESQPLIGT 1717
            +  Y V +      I+      +   DT   L GL+P + Y + V A             
Sbjct: 939  IISYTVVFRD----INSQQELQNITTDTRFTLTGLKPDTTYDIKVRAWTSKGSGPLSPSI 994

Query: 1718 QSTAIPA----PTDLKFTQVTPTSLSAQWTPPN 1746
            QS  +P       + +      TS+   W  P+
Sbjct: 995  QSRTMPVEQVFAKNFRVAAAMKTSVLLSWEVPD 1027



 Score =  130 bits (328), Expect = 1e-29
 Identities = 177/732 (24%), Positives = 297/732 (40%), Gaps = 84/732 (11%)

Query: 1308 EEDVAELSISPSDNAVVLTNLLPGTEYV-VSVSSV--YEQHESTPLRGRQKTGLDSPTGI 1364
            EE   E  +    N + L+N++    Y  V++SS+   E      ++   K  +D    +
Sbjct: 270  EELTKEDEMPVGRNVLELSNVVRSANYTCVAISSLGMIEATAQVTVKALPKPPID----L 325

Query: 1365 DFSDITANSFTVHWIAPRAT-ITGYRIRHHPEHFSGRPRE-DRVPHSRNSITLTNLTPGT 1422
              ++ TA S T+ W +  +  +T Y I++      G  +E D V  +R SI    L+P +
Sbjct: 326  VVTETTATSVTLTWDSGNSEPVTYYGIQYRAAGTEGPFQEVDGVATTRYSIG--GLSPFS 383

Query: 1423 EYVVSIVALNGREESP------LLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVT-- 1474
            EY   ++A+N     P         G+Q+  S  PR ++    + +++L+ W+ P     
Sbjct: 384  EYAFRVLAVNSIGRGPPSEAVRARTGEQAP-SSPPRRVQARMLSASTMLVQWEPPEEPNG 442

Query: 1475 -VRYYRITYGETGGNSPV---QEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPAS 1530
             VR YR+ Y       P    +  T  G  +T  +  L PG+ Y++ V A T  GD P S
Sbjct: 443  LVRGYRVYYTPDSRRPPNAWHKHNTDAGLLTT--VGSLLPGITYSLRVLAFTAVGDGPPS 500

Query: 1531 SKPISINYRTEIDKPSQ---MQVTDVQDNSISVKWL-PSSSPVTGYRVTTTPKNGPGPTK 1586
                +I  +T+   P+Q    Q     D  I + WL P    +  Y +            
Sbjct: 501  P---TIQVKTQQGVPAQPADFQAEVESDTRIQLSWLLPPQERIIMYELVYWAAEDEDQQH 557

Query: 1587 TKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGES--QPLVQTAV---TNIDRPKGLAFT 1641
              T  P  +  T+E L+P   Y   + A++  G     P ++      T    P+ +   
Sbjct: 558  KVTFDPTSS-YTLEDLKPDTLYRFQLAARSDMGVGVFTPTIEARTAQSTPSAPPQKVMCV 616

Query: 1642 DVDVDSIKIAWESP-----QGQVSRYRVTYSSP--EDGIHELFPAPDGEEDTAELQGLRP 1694
             +   +++++W  P      G +++Y V Y +   ED    +      E  + +L GL  
Sbjct: 617  SMGSTTVRVSWVPPPADSRNGVITQYSVAYEAVDGEDRGRHVVDGISREHSSWDLVGLEK 676

Query: 1695 GSEYTVSVVALHDDM----ESQPLIGTQSTAIPA--PTDLKFTQVTPTSLSAQWTPP--- 1745
             +EY V V A H D+    ES P++      +P+  P  ++   +  T++   W  P   
Sbjct: 677  WTEYRVWVRA-HTDVGPGPESSPVLVRTDEDVPSGPPRKVEVEPLNSTAVHVYWKLPVPS 735

Query: 1746 --NVQLTGYRVRVTPKEKTGP-----MKEINLAPDSSSVVVSGLMVATKYEVSVYALK-- 1796
              + Q+ GY+V     E   P     ++++ LA ++    +SGL   T Y V+V A    
Sbjct: 736  KQHGQIRGYQVTYVRLENGEPRGLPIIQDVMLA-EAQETTISGLTPETTYSVTVAAYTTK 794

Query: 1797 -DTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTET---ITGFQVDAVPAN 1852
             D   S+P   +VTT   V       ++     T  + W    E    + G+++    A+
Sbjct: 795  GDGARSKPK--IVTTTGAVPGRPTMMISTTAMNTALLQWHPPKELPGELLGYRLQYCRAD 852

Query: 1853 GQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPS----N 1908
               P       D + +T+TGL  GT Y   L   N          +  T  D PS    N
Sbjct: 853  EARPNTIDFGKDDQHFTVTGLHKGTTYIFRLAAKNRAGLGEEFEKEIRTPEDLPSGFPQN 912

Query: 1909 LRFLATTPNSLLVSWQPP-----RARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGL 1963
            L     T ++  ++W PP       RI  Y + +    S   +   +     T  T+TGL
Sbjct: 913  LHVTGLTTSTTELAWDPPVLAERNGRIISYTVVFRDINS---QQELQNITTDTRFTLTGL 969

Query: 1964 EPGTEYTIYVIA 1975
            +P T Y I V A
Sbjct: 970  KPDTTYDIKVRA 981



 Score =  117 bits (293), Expect = 1e-25
 Identities = 188/815 (23%), Positives = 313/815 (38%), Gaps = 87/815 (10%)

Query: 862  ANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQ----ETTGTPRSDTVPSPR-DLQFV 916
            A  +T  D  P  +  + +  V  +   T V I      E T       +P P  DL   
Sbjct: 269  AEELTKEDEMPVGRNVLELSNVVRSANYTCVAISSLGMIEATAQVTVKALPKPPIDLVVT 328

Query: 917  EVTDVKVTIMWTPPESA-VTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYF 975
            E T   VT+ W    S  VT Y +        G   Q +     T   + GLSP   Y F
Sbjct: 329  ETTATSVTLTWDSGNSEPVTYYGIQYRAAGTEGPF-QEVDGVATTRYSIGGLSPFSEYAF 387

Query: 976  KVFAVS---HGRESKPLTAQ--QTTKLDAPTNLQFVNETDSTVLVRWTP---PRAQITGY 1027
            +V AV+    G  S+ + A+  +      P  +Q    + ST+LV+W P   P   + GY
Sbjct: 388  RVLAVNSIGRGPPSEAVRARTGEQAPSSPPRRVQARMLSASTMLVQWEPPEEPNGLVRGY 447

Query: 1028 RLTVGLTRRGQP---RQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTT 1084
            R+      R  P    ++N    +    + +L P   Y++ ++A     + P +  +   
Sbjct: 448  RVYYTPDSRRPPNAWHKHNTDAGLLT-TVGSLLPGITYSLRVLAFTAVGDGPPSPTIQVK 506

Query: 1085 LQPGSSIPP--YNTEV-TETTIVITWTPAPR---IGFKLGVRPSQGGEAPREVTSD-SGS 1137
             Q G    P  +  EV ++T I ++W   P+   I ++L    ++  +   +VT D + S
Sbjct: 507  TQQGVPAQPADFQAEVESDTRIQLSWLLPPQERIIMYELVYWAAEDEDQQHKVTFDPTSS 566

Query: 1138 IVVSGLTPGVEYVYTIQVLRD-GQERDAPIVNKVV---TPLSPPTNLHLEANPDTGVLTV 1193
              +  L P   Y + +    D G     P +       TP +PP  +   +   T V  V
Sbjct: 567  YTLEDLKPDTLYRFQLAARSDMGVGVFTPTIEARTAQSTPSAPPQKVMCVSMGSTTV-RV 625

Query: 1194 SW----ERSTTPDITGYRITTTPTNGQ-QGNSLEEVVHADQSSCTFDNLSPGLEYNVSVY 1248
            SW      S    IT Y +     +G+ +G  + + +  + SS     L    EY V V 
Sbjct: 626  SWVPPPADSRNGVITQYSVAYEAVDGEDRGRHVVDGISREHSSWDLVGLEKWTEYRVWVR 685

Query: 1249 TVKD---DKESVPI---SDTIIPAVPPPTDLRFTNIGPDTMRVTW-APPPSI---DLTNF 1298
               D     ES P+   +D  +P+  PP  +    +    + V W  P PS     +  +
Sbjct: 686  AHTDVGPGPESSPVLVRTDEDVPS-GPPRKVEVEPLNSTAVHVYWKLPVPSKQHGQIRGY 744

Query: 1299 LVRYSPVKNEED-----VAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGR 1353
             V Y  ++N E      + ++ ++ +    + + L P T Y V+V++   + +      R
Sbjct: 745  QVTYVRLENGEPRGLPIIQDVMLAEAQETTI-SGLTPETTYSVTVAAYTTKGDG----AR 799

Query: 1354 QKTGLDSPTG-------IDFSDITANSFTVHWIAPR---ATITGYRIRHHPEHFSGRPRE 1403
             K  + + TG       +  S    N+  + W  P+     + GYR+++       RP  
Sbjct: 800  SKPKIVTTTGAVPGRPTMMISTTAMNTALLQWHPPKELPGELLGYRLQYCRAD-EARPNT 858

Query: 1404 DRVPHSRNSITLTNLTPGTEYVVSIVALN----GREESPLLIGQQSTVSDVPRDLEVVAA 1459
                      T+T L  GT Y+  + A N    G E    +   +   S  P++L V   
Sbjct: 859  IDFGKDDQHFTVTGLHKGTTYIFRLAAKNRAGLGEEFEKEIRTPEDLPSGFPQNLHVTGL 918

Query: 1460 TPTSLLISWDAPAVTVR-----YYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDY 1514
            T ++  ++WD P +  R      Y + + +      +Q  T   + +  T++GLKP   Y
Sbjct: 919  TTSTTELAWDPPVLAERNGRIISYTVVFRDINSQQELQNIT---TDTRFTLTGLKPDTTY 975

Query: 1515 TITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKW-LPSSSPVTGYR 1573
             I V A T +G  P S    S     E       +V      S+ + W +P S     Y+
Sbjct: 976  DIKVRAWTSKGSGPLSPSIQSRTMPVEQVFAKNFRVAAAMKTSVLLSWEVPDS-----YK 1030

Query: 1574 VTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEY 1608
                 K        +  G    ++ I  LQP  EY
Sbjct: 1031 SAVPFKILYNGQSVEVDGHSMRKL-IADLQPNTEY 1064



 Score =  114 bits (285), Expect = 1e-24
 Identities = 171/774 (22%), Positives = 289/774 (37%), Gaps = 82/774 (10%)

Query: 990  TAQQTTKL--DAPTNLQFVNETDSTVLVRWTPPRAQ-ITGYRLTVGLTRRGQPRQYNVGP 1046
            TAQ T K     P +L     T ++V + W    ++ +T Y +         P Q   G 
Sbjct: 310  TAQVTVKALPKPPIDLVVTETTATSVTLTWDSGNSEPVTYYGIQYRAAGTEGPFQEVDGV 369

Query: 1047 SVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGV-FTTLQPGSSIPPYNTE---VTETT 1102
            + ++Y +  L P SEY   ++A+      P +  V   T +   S PP   +   ++ +T
Sbjct: 370  ATTRYSIGGLSPFSEYAFRVLAVNSIGRGPPSEAVRARTGEQAPSSPPRRVQARMLSAST 429

Query: 1103 IVITWTPAPR-----IGFKLGVRPS--QGGEAPREVTSDSGSI-VVSGLTPGVEY---VY 1151
            +++ W P         G+++   P   +   A  +  +D+G +  V  L PG+ Y   V 
Sbjct: 430  MLVQWEPPEEPNGLVRGYRVYYTPDSRRPPNAWHKHNTDAGLLTTVGSLLPGITYSLRVL 489

Query: 1152 TIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTT 1211
                + DG       V       + P +   E   DT +  +SW       I  Y +   
Sbjct: 490  AFTAVGDGPPSPTIQVKTQQGVPAQPADFQAEVESDTRI-QLSWLLPPQERIIMYELVYW 548

Query: 1212 PTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESV---PISDTIIPAVP 1268
                +  +   +V     SS T ++L P   Y   +    D    V    I      + P
Sbjct: 549  AAEDE--DQQHKVTFDPTSSYTLEDLKPDTLYRFQLAARSDMGVGVFTPTIEARTAQSTP 606

Query: 1269 --PPTDLRFTNIGPDTMRVTWAPPPSID----LTNFLVRYSPVKNEEDVAEL--SISPSD 1320
              PP  +   ++G  T+RV+W PPP+      +T + V Y  V  E+    +   IS   
Sbjct: 607  SAPPQKVMCVSMGSTTVRVSWVPPPADSRNGVITQYSVAYEAVDGEDRGRHVVDGISREH 666

Query: 1321 NAVVLTNLLPGTEYVVSV---SSVYEQHESTPLRGRQKTGLDS--PTGIDFSDITANSFT 1375
            ++  L  L   TEY V V   + V    ES+P+  R    + S  P  ++   + + +  
Sbjct: 667  SSWDLVGLEKWTEYRVWVRAHTDVGPGPESSPVLVRTDEDVPSGPPRKVEVEPLNSTAVH 726

Query: 1376 VHWIAP-----RATITGYRIRHHPEHFSGRPR-----EDRVPHSRNSITLTNLTPGTEYV 1425
            V+W  P        I GY++  +    +G PR     +D +       T++ LTP T Y 
Sbjct: 727  VYWKLPVPSKQHGQIRGYQVT-YVRLENGEPRGLPIIQDVMLAEAQETTISGLTPETTYS 785

Query: 1426 VSIVAL----NGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAV---TVRYY 1478
            V++ A     +G    P ++     V   P  +    A  T+LL  W  P      +  Y
Sbjct: 786  VTVAAYTTKGDGARSKPKIVTTTGAVPGRPTMMISTTAMNTALL-QWHPPKELPGELLGY 844

Query: 1479 RITYGETGGNSPVQEFTVPGSKSTA--TISGLKPGVDYTITVYAVTGRGDSPASSKPISI 1536
            R+ Y       P    T+   K     T++GL  G  Y   + A    G      K I  
Sbjct: 845  RLQYCRADEARP---NTIDFGKDDQHFTVTGLHKGTTYIFRLAAKNRAGLGEEFEKEIRT 901

Query: 1537 NYRTEIDKPSQMQVTDVQDNSISVKWLP-----SSSPVTGYRVTTTPKNGPGPTKTKTAG 1591
                    P  + VT +  ++  + W P      +  +  Y V     N     +  T  
Sbjct: 902  PEDLPSGFPQNLHVTGLTTSTTELAWDPPVLAERNGRIISYTVVFRDINSQQELQNITT- 960

Query: 1592 PDQTEMTIEGLQPTVEYVVSV--YAQNPSGESQPLVQTAVTNIDR--PKGLAFTDVDVDS 1647
               T  T+ GL+P   Y + V  +    SG   P +Q+    +++   K          S
Sbjct: 961  --DTRFTLTGLKPDTTYDIKVRAWTSKGSGPLSPSIQSRTMPVEQVFAKNFRVAAAMKTS 1018

Query: 1648 IKIAWESPQGQVSR--YRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYT 1699
            + ++WE P    S   +++ Y+     +       DG      +  L+P +EY+
Sbjct: 1019 VLLSWEVPDSYKSAVPFKILYNGQSVEV-------DGHSMRKLIADLQPNTEYS 1065



 Score =  105 bits (261), Expect = 7e-22
 Identities = 198/893 (22%), Positives = 353/893 (39%), Gaps = 110/893 (12%)

Query: 1087 PGSSIPPYNTEV-----TETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVS 1141
            P  SIPP + EV        T V    P P + + +G       +   E+      + +S
Sbjct: 232  PRFSIPPSSQEVMPGGSVNLTCVAVGAPMPYVKWMMGAEELTKED---EMPVGRNVLELS 288

Query: 1142 GLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTP 1201
             +     Y           E  A +  K +    PP +L +     T V T++W+   + 
Sbjct: 289  NVVRSANYTCVAISSLGMIEATAQVTVKALP--KPPIDLVVTETTATSV-TLTWDSGNSE 345

Query: 1202 DITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKD-----DKES 1256
             +T Y I      G +G   +EV     +  +   LSP  EY   V  V         E+
Sbjct: 346  PVTYYGIQYRAA-GTEG-PFQEVDGVATTRYSIGGLSPFSEYAFRVLAVNSIGRGPPSEA 403

Query: 1257 VPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPP--PSIDLTNFLVRYSPVKNEEDVAEL 1314
            V           PP  ++   +   TM V W PP  P+  +  + V Y+P       A  
Sbjct: 404  VRARTGEQAPSSPPRRVQARMLSASTMLVQWEPPEEPNGLVRGYRVYYTPDSRRPPNAWH 463

Query: 1315 SISPSDNAVVLT--NLLPGTEY---VVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDI 1369
              + +D  ++ T  +LLPG  Y   V++ ++V +   S  ++ + + G+ +      +++
Sbjct: 464  KHN-TDAGLLTTVGSLLPGITYSLRVLAFTAVGDGPPSPTIQVKTQQGVPAQPADFQAEV 522

Query: 1370 TANS-FTVHWIAP-RATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVS 1427
             +++   + W+ P +  I  Y + +       +  +     + +S TL +L P T Y   
Sbjct: 523  ESDTRIQLSWLLPPQERIIMYELVYWAAEDEDQQHKVTFDPT-SSYTLEDLKPDTLYRFQ 581

Query: 1428 IVALNGREE---SPLLIGQ--QSTVSDVPRDLEVVAATPTSLLISWDAPAVTVR-----Y 1477
            + A +       +P +  +  QST S  P+ +  V+   T++ +SW  P    R      
Sbjct: 582  LAARSDMGVGVFTPTIEARTAQSTPSAPPQKVMCVSMGSTTVRVSWVPPPADSRNGVITQ 641

Query: 1478 YRITY----GETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKP 1533
            Y + Y    GE  G   V    +    S+  + GL+   +Y + V A T  G  P SS P
Sbjct: 642  YSVAYEAVDGEDRGRHVVDG--ISREHSSWDLVGLEKWTEYRVWVRAHTDVGPGPESS-P 698

Query: 1534 ISINYRTEIDKPS----QMQVTDVQDNSISVKW---LPSSS--PVTGYRVTTTP-KNGPG 1583
            + +  RT+ D PS    +++V  +   ++ V W   +PS     + GY+VT    +NG  
Sbjct: 699  VLV--RTDEDVPSGPPRKVEVEPLNSTAVHVYWKLPVPSKQHGQIRGYQVTYVRLENGEP 756

Query: 1584 ---PTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE---SQPLVQTAVTNIDRPKG 1637
               P        +  E TI GL P   Y V+V A    G+   S+P + T    +     
Sbjct: 757  RGLPIIQDVMLAEAQETTISGLTPETTYSVTVAAYTTKGDGARSKPKIVTTTGAVPGRPT 816

Query: 1638 LAFTDVDVDSIKIAWESPQ---GQVSRYRVTYSSPEDGIHELFPAPDGEEDTA-ELQGLR 1693
            +  +   +++  + W  P+   G++  YR+ Y   ++          G++D    + GL 
Sbjct: 817  MMISTTAMNTALLQWHPPKELPGELLGYRLQYCRADEARPNTIDF--GKDDQHFTVTGLH 874

Query: 1694 PGSEYTVSVVA-----LHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPP--- 1745
             G+ Y   + A     L ++ E + +   +      P +L  T +T ++    W PP   
Sbjct: 875  KGTTYIFRLAAKNRAGLGEEFEKE-IRTPEDLPSGFPQNLHVTGLTTSTTELAWDPPVLA 933

Query: 1746 --NVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRP 1803
              N ++  Y V           +E+      +   ++GL   T Y++ V A     TS+ 
Sbjct: 934  ERNGRIISYTVVF---RDINSQQELQNITTDTRFTLTGLKPDTTYDIKVRAW----TSKG 986

Query: 1804 AQGVVTTLENVSPP------RRARVTDATETTITISWRTKTETITGFQVDAVPA----NG 1853
            +  +  ++++ + P      +  RV  A +T++ +SW      +      AVP     NG
Sbjct: 987  SGPLSPSIQSRTMPVEQVFAKNFRVAAAMKTSVLLSWE-----VPDSYKSAVPFKILYNG 1041

Query: 1854 QTPIQRTIKPDVRSYT--ITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAID 1904
            Q+     ++ D  S    I  LQP T+Y   L     +A     ++   TA D
Sbjct: 1042 QS-----VEVDGHSMRKLIADLQPNTEYSFVLMNRGSSAGGLQHLVSIRTAPD 1089



 Score = 86.7 bits (213), Expect = 2e-16
 Identities = 125/566 (22%), Positives = 223/566 (39%), Gaps = 67/566 (11%)

Query: 628  IQWNAPQPSHISKY-ILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQ 686
            + W  P    I  Y ++ W  ++   + K    P   +SYT++ LKP  +Y  QL +   
Sbjct: 530  LSWLLPPQERIIMYELVYWAAEDEDQQHKVTFDP--TSSYTLEDLKPDTLYRFQLAARSD 587

Query: 687  YGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWV----- 741
             G    T      T+ STP         + P   ++  S   T +      VSWV     
Sbjct: 588  MGVGVFTPTIEARTAQSTP---------SAPPQKVMCVSMGSTTVR-----VSWVPPPAD 633

Query: 742  SASDTVSGFRVEYELSEEGDEPQYL--DLPSTATSVNIPDLLPGRKYIVNVYQISEDG-- 797
            S +  ++ + V YE  +  D  +++   +    +S ++  L    +Y V V   ++ G  
Sbjct: 634  SRNGVITQYSVAYEAVDGEDRGRHVVDGISREHSSWDLVGLEKWTEYRVWVRAHTDVGPG 693

Query: 798  -EQSLILSTSQTTAPDAPPDPT-VDQVDDTSIVVRW-----SRPQAPITGYRIVYSPSVE 850
             E S +L  +    P  PP    V+ ++ T++ V W     S+    I GY++ Y     
Sbjct: 694  PESSPVLVRTDEDVPSGPPRKVEVEPLNSTAVHVYWKLPVPSKQHGQIRGYQVTYVRLEN 753

Query: 851  GSSTELNLPE-----TANSVTLSDLQPGVQYNITIYAVE---ENQESTPVVIQQETTGTP 902
            G    L + +      A   T+S L P   Y++T+ A     +   S P ++   TTG  
Sbjct: 754  GEPRGLPIIQDVMLAEAQETTISGLTPETTYSVTVAAYTTKGDGARSKPKIV--TTTG-- 809

Query: 903  RSDTVPSPRDLQFVEVTDVKVTIM-WTPPE---SAVTGYRVDVIPVNLPGEHGQRLPISR 958
                VP  R    +  T +   ++ W PP+     + GYR+     +    +        
Sbjct: 810  ---AVPG-RPTMMISTTAMNTALLQWHPPKELPGELLGYRLQYCRADEARPNTIDFGKDD 865

Query: 959  NTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPT----NLQFVNETDSTVL 1014
              F  VTGL  G TY F++ A +     +    +  T  D P+    NL     T ST  
Sbjct: 866  QHFT-VTGLHKGTTYIFRLAAKNRAGLGEEFEKEIRTPEDLPSGFPQNLHVTGLTTSTTE 924

Query: 1015 VRWTPP-RAQITGYRLTVGLTRR---GQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIK 1070
            + W PP  A+  G  ++  +  R    Q    N+  + +++ L  L+P + Y + + A  
Sbjct: 925  LAWDPPVLAERNGRIISYTVVFRDINSQQELQNI-TTDTRFTLTGLKPDTTYDIKVRAWT 983

Query: 1071 GNQESPKATGVFTTLQPGSSIPPYNTEVT---ETTIVITWTPAPRIGFKLGVRPSQGGEA 1127
                 P +  + +   P   +   N  V    +T+++++W         +  +    G++
Sbjct: 984  SKGSGPLSPSIQSRTMPVEQVFAKNFRVAAAMKTSVLLSWEVPDSYKSAVPFKILYNGQS 1043

Query: 1128 PREVTSDSGSIVVSGLTPGVEYVYTI 1153
              EV   S   +++ L P  EY + +
Sbjct: 1044 V-EVDGHSMRKLIADLQPNTEYSFVL 1068


>gi|119220552 sidekick 1 [Homo sapiens]
          Length = 2213

 Score =  152 bits (383), Expect = 5e-36
 Identities = 270/1177 (22%), Positives = 447/1177 (37%), Gaps = 183/1177 (15%)

Query: 923  VTIMWTPP---ESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFA 979
            V + W  P    S +  Y V++   N P +          T   V+GL+P  TY F+V A
Sbjct: 686  VVLSWVRPFDGNSPILYYIVELSENNSPWKVHLSNVGPEMTGVTVSGLTPARTYQFRVCA 745

Query: 980  VS------HGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP---------RAQI 1024
            V+      +  E+  L   +      P N+     T+ +++V+W PP         R  I
Sbjct: 746  VNEVGRGQYSAETSRLMLPEEPPSAPPKNIVASGRTNQSIMVQWQPPPETEHNGVLRGYI 805

Query: 1025 TGYRLTVGLTRRGQPRQYNV-GPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFT 1083
              YRL  GL   G+ +Q N+  P V+   + +L   ++Y + + A  G        GVF+
Sbjct: 806  LRYRLA-GLP--GEYQQRNITSPEVNYCLVTDLIIWTQYEIQVAAYNG-----AGLGVFS 857

Query: 1084 ------TLQPGSSIPPYNTE---VTETTIVITWTPAPRI-------GFKLGVRPSQGGEA 1127
                  TLQ   + PP N +   V  TTI   W P P+        G+KL   P+   EA
Sbjct: 858  RAVTEYTLQGVPTAPPQNVQTEAVNSTTIQFLWNPPPQQFINGINQGYKLLAWPADAPEA 917

Query: 1128 PREVT--SDSGSIVVSGLTPGVEYV-YTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEA 1184
               VT   D   +    +T   ++  Y   VL      D P       P +P      E 
Sbjct: 918  VTVVTIAPDFHGVHHGHITNLKKFTAYFTSVLCFTTPGDGP-------PSTPQLVWTQED 970

Query: 1185 NP------------DTGVLTVSWERSTTPD--ITGYRITTTPTNGQQGNSLEEVVHADQS 1230
             P            DT  L VSW+     +  ITGY+I+     G+  + L   +++   
Sbjct: 971  KPGAVGHLSFTEILDTS-LKVSWQEPLEKNGIITGYQISWE-VYGRNDSRLTHTLNSTTH 1028

Query: 1231 SCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPP-----PTDLRFTNIGPDTMRV 1285
                  LS    Y + V  V      +  S TI   VPP     P++L  +NI P +  +
Sbjct: 1029 EYKIQGLSSLTTYTIDVAAVTAVGTGLVTSSTISSGVPPDLPGAPSNLVISNISPRSATL 1088

Query: 1286 TWAP--PPSIDLTNFLV--RYSPVKNEED---VAELSISPSDNAVVLTNLLPGTEYVVSV 1338
             + P       ++ ++V  +   + +EE+   + E    P    + + NL P T Y   +
Sbjct: 1089 QFRPGYDGKTSISRWIVEGQVGAIGDEEEWVTLYEEENEPDAQMLEIPNLTPYTHYRFRM 1148

Query: 1339 SSVY------EQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIA-------PRATI 1385
              V           S  ++  Q     +PT +     +  S  + W+             
Sbjct: 1149 KQVNIVGPSPYSPSSRVIQTLQAPPDVAPTSVTVRTASETSLRLRWVPLPDSQYNGNPES 1208

Query: 1386 TGYRIRHHPEHFSGRPREDRVPHS-RNSITLTNLTPGTEYVVSIVALNGREESP---LLI 1441
             GYRI++             V        T+  L    EY + + A N     P   ++ 
Sbjct: 1209 VGYRIKYWRSDLQSSAVAQVVSDRLEREFTIEELEEWMEYELQMQAFNAVGAGPWSEVVR 1268

Query: 1442 GQ--QSTVSDVPRDLEVVAATPTSLLISWDAPAVT-----VRYYRITYGETGGNSPVQEF 1494
            G+  +S  S  P ++   A + T +L++W +         +  Y+I +     +   +  
Sbjct: 1269 GRTRESVPSAAPENVSAEAVSSTQILLTWTSVPEQDQNGLILGYKILFRAKDLDPEPRSH 1328

Query: 1495 TVPGSKS-TATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPS---QMQV 1550
             V G+ + +A ++GL+  V Y + V A T  G+   S+ P+ +  RT+ D P    ++  
Sbjct: 1329 IVRGNHTQSALLAGLRKFVLYELQVLAFTRIGNGVPST-PLILE-RTKDDAPGPPVRLVF 1386

Query: 1551 TDVQDNSISVKWLPSSSP---VTGYRVT-TTPKNGPGPTKTKTAGPDQTEMTIEGLQPTV 1606
             +V+  S+ + W P   P   + GY++      + P    T   G    + T   L P  
Sbjct: 1387 PEVRLTSVRIVWQPPEEPNGIILGYQIAYRLASSSPHTFTTVEVGATVRQFTATDLAPES 1446

Query: 1607 EYVVSVYAQNPSGESQPLVQTAVTNIDR-----PKGLAFTDVDVD--SIKIAWESPQGQV 1659
             Y+  + A+   G  +PL  T +T   R     P+ L     +V   S+++ W       
Sbjct: 1447 AYIFRLSAKTRQGWGEPLEATVITTEKRERPAPPRELLVPQAEVTARSLRLQWVPGSDGA 1506

Query: 1660 SRYRVTYSSPED---GIHELFPAPDGEEDTA-ELQGLRPGSEYTVSVVALHD----DMES 1711
            S  R       +   G  + + +    E TA  +  LRP + Y + + A +D    D  S
Sbjct: 1507 SPIRYFTMQVRELPRGEWQTYSSSISHEATACVVDRLRPFTSYKLRLKATNDIGDSDFSS 1566

Query: 1712 QPLIGTQSTAIPA--PTDLKFTQVTPTSLSAQWTPP-----NVQLTGYRVRVTPKE---- 1760
            +    T    +P   P  +  T  T +S+  QW PP     N  L GYR+     E    
Sbjct: 1567 ETEAVTTLQDVPGEPPGSVSATPHTTSSVLIQWQPPRDESLNGLLQGYRIYYRELEYEAG 1626

Query: 1761 -----KT--------------GPMKEINLAPDSSSVVVSGLMVATKYEVSVYA---LKDT 1798
                 KT                 K +N +  S+   ++ L    +YEV + A   + ++
Sbjct: 1627 SGTEAKTLKNPIALHAELTAQSSFKTVNSSSTSTMCELTHLKKYRRYEVIMTAYNIIGES 1686

Query: 1799 LTSRPAQGVVTTLENVSPPRRARVTDATETTITISW-----RTKTETITGFQVDAVPANG 1853
              S P +  V        P+  +VT  T + + ++W      ++   I G+++    A+ 
Sbjct: 1687 PASAPVEVFVGEAAPAMAPQNVQVTPLTASQLEVTWDPPPPESQNGNIQGYKIYYWEADS 1746

Query: 1854 QTPIQRTI-----KPDVRSYTITGLQPGTDYKIYLYTLN---DNARSSPVVIDASTAID- 1904
            Q   ++       +P VR   +T     T Y + +   N   D  +S P       A   
Sbjct: 1747 QNETEKMKVLFLPEPVVRLKNLTS---HTKYLVSISAFNAAGDGPKSDPQQGRTHQAAPG 1803

Query: 1905 APSNLRFLATTPNSLLVSWQPPRAR---ITGYIIKYE 1938
            APS L F   T  +L VSW  P A    + GY + YE
Sbjct: 1804 APSFLAFSEITSTTLNVSWGEPAAANGILQGYRVVYE 1840



 Score =  150 bits (378), Expect = 2e-35
 Identities = 280/1336 (20%), Positives = 488/1336 (36%), Gaps = 191/1336 (14%)

Query: 737  VVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTA---TSVNIPDLLPGRKYIVNVYQI 793
            V+SWV   D  S          E + P  + L +     T V +  L P R Y   V  +
Sbjct: 687  VLSWVRPFDGNSPILYYIVELSENNSPWKVHLSNVGPEMTGVTVSGLTPARTYQFRVCAV 746

Query: 794  SEDGEQSLILSTSQTTAPDAPPDPTVDQV-----DDTSIVVRWSRP---------QAPIT 839
            +E G       TS+   P+ PP      +      + SI+V+W  P         +  I 
Sbjct: 747  NEVGRGQYSAETSRLMLPEEPPSAPPKNIVASGRTNQSIMVQWQPPPETEHNGVLRGYIL 806

Query: 840  GYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETT 899
             YR+   P  E     +  PE  N   ++DL    QY I + A   N     V  +  T 
Sbjct: 807  RYRLAGLPG-EYQQRNITSPE-VNYCLVTDLIIWTQYEIQVAAY--NGAGLGVFSRAVTE 862

Query: 900  GTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAV-----TGYRVDVIPVNLPGEHGQRL 954
             T +      P+++Q   V    +  +W PP          GY++   P + P E    +
Sbjct: 863  YTLQGVPTAPPQNVQTEAVNSTTIQFLWNPPPQQFINGINQGYKLLAWPADAP-EAVTVV 921

Query: 955  PISRN----TFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQ----QTTKLDAPTNLQFV 1006
             I+ +        +T L     Y+  V   +   +  P T Q    Q  K  A  +L F 
Sbjct: 922  TIAPDFHGVHHGHITNLKKFTAYFTSVLCFTTPGDGPPSTPQLVWTQEDKPGAVGHLSFT 981

Query: 1007 NETDSTVLVRWTPPRAQ---ITGYRLTVGLTRRGQPR-QYNVGPSVSKYPLRNLQPASEY 1062
               D+++ V W  P  +   ITGY+++  +  R   R  + +  +  +Y ++ L   + Y
Sbjct: 982  EILDTSLKVSWQEPLEKNGIITGYQISWEVYGRNDSRLTHTLNSTTHEYKIQGLSSLTTY 1041

Query: 1063 TVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPS 1122
            T+ + A+     +   TG+ T+    S +PP         ++   +P       L  RP 
Sbjct: 1042 TIDVAAV-----TAVGTGLVTSSTISSGVPPDLPGAPSNLVISNISPR---SATLQFRPG 1093

Query: 1123 QGGEA------------------------PREVTSDSGSIVVSGLTPGVEYVYTI-QVLR 1157
              G+                           E   D+  + +  LTP   Y + + QV  
Sbjct: 1094 YDGKTSISRWIVEGQVGAIGDEEEWVTLYEEENEPDAQMLEIPNLTPYTHYRFRMKQVNI 1153

Query: 1158 DGQERDAPIVNKVVTPLSP----PTNLHLEANPDTGVLTVSW------ERSTTPDITGYR 1207
             G    +P    + T  +P    PT++ +    +T  L + W      + +  P+  GYR
Sbjct: 1154 VGPSPYSPSSRVIQTLQAPPDVAPTSVTVRTASETS-LRLRWVPLPDSQYNGNPESVGYR 1212

Query: 1208 ITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVY---TVKDDKESVPISDTII 1264
            I    ++ Q     + V    +   T + L   +EY + +     V     S  +     
Sbjct: 1213 IKYWRSDLQSSAVAQVVSDRLEREFTIEELEEWMEYELQMQAFNAVGAGPWSEVVRGRTR 1272

Query: 1265 PAVP--PPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDV-----AELSIS 1317
             +VP   P ++    +    + +TW   P  D    ++ Y  +   +D+     + +   
Sbjct: 1273 ESVPSAAPENVSAEAVSSTQILLTWTSVPEQDQNGLILGYKILFRAKDLDPEPRSHIVRG 1332

Query: 1318 PSDNAVVLTNLLPGTEY---VVSVSSVYEQHESTPLRGRQKTGLDS---PTGIDFSDITA 1371
                + +L  L     Y   V++ + +     STPL   ++T  D+   P  + F ++  
Sbjct: 1333 NHTQSALLAGLRKFVLYELQVLAFTRIGNGVPSTPLI-LERTKDDAPGPPVRLVFPEVRL 1391

Query: 1372 NSFTVHW---IAPRATITGYRIRHHPEHFSGRP-REDRVPHSRNSITLTNLTPGTEYVVS 1427
             S  + W     P   I GY+I +     S        V  +    T T+L P + Y+  
Sbjct: 1392 TSVRIVWQPPEEPNGIILGYQIAYRLASSSPHTFTTVEVGATVRQFTATDLAPESAYIFR 1451

Query: 1428 IVALNGRE-----ESPLLIGQQSTVSDVPRDLEVVAA--TPTSLLISW---DAPAVTVRY 1477
            + A   +      E+ ++  ++      PR+L V  A  T  SL + W      A  +RY
Sbjct: 1452 LSAKTRQGWGEPLEATVITTEKRERPAPPRELLVPQAEVTARSLRLQWVPGSDGASPIRY 1511

Query: 1478 YRITYGE-TGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISI 1536
            + +   E   G       ++    +   +  L+P   Y + + A    GDS  SS+  ++
Sbjct: 1512 FTMQVRELPRGEWQTYSSSISHEATACVVDRLRPFTSYKLRLKATNDIGDSDFSSETEAV 1571

Query: 1537 NYRTEI--DKPSQMQVTDVQDNSISVKWLPS-----SSPVTGYRV--------------T 1575
                ++  + P  +  T    +S+ ++W P      +  + GYR+               
Sbjct: 1572 TTLQDVPGEPPGSVSATPHTTSSVLIQWQPPRDESLNGLLQGYRIYYRELEYEAGSGTEA 1631

Query: 1576 TTPKN---------GPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQ 1626
             T KN              KT  +    T   +  L+    Y V + A N  GES     
Sbjct: 1632 KTLKNPIALHAELTAQSSFKTVNSSSTSTMCELTHLKKYRRYEVIMTAYNIIGESPASAP 1691

Query: 1627 TAV-----TNIDRPKGLAFTDVDVDSIKIAW-----ESPQGQVSRYRVTY-SSPEDGIHE 1675
              V          P+ +  T +    +++ W     ES  G +  Y++ Y  +      E
Sbjct: 1692 VEVFVGEAAPAMAPQNVQVTPLTASQLEVTWDPPPPESQNGNIQGYKIYYWEADSQNETE 1751

Query: 1676 LFPAPDGEEDTAELQGLRPGSEYTVSVVALH---DDMESQPLIGTQSTAIP-APTDLKFT 1731
                    E    L+ L   ++Y VS+ A +   D  +S P  G    A P AP+ L F+
Sbjct: 1752 KMKVLFLPEPVVRLKNLTSHTKYLVSISAFNAAGDGPKSDPQQGRTHQAAPGAPSFLAFS 1811

Query: 1732 QVTPTSLSAQWTPP---NVQLTGYRV------------RVTPKEKTGPMKEINLAPDSSS 1776
            ++T T+L+  W  P   N  L GYRV            +V   E  G  +      D + 
Sbjct: 1812 EITSTTLNVSWGEPAAANGILQGYRVVYEPLAPVQGVSKVVTVEVRGNWQRWLKVRDLTK 1871

Query: 1777 VVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISW-- 1834
             V     V  +       L+  +T+ PA+G      +   PR   VT +  + +T+ W  
Sbjct: 1872 GVTYFFRVQARTITYGPELQANITAGPAEG------SPGSPRDVLVTKSA-SELTLQWTE 1924

Query: 1835 -RTKTETITGFQVDAVPANG--QTPIQRTIKPDVRSYTIT--GLQPGTDYKIYLYTLNDN 1889
              +     TG+ ++A P++        + I     SYT++   L+ G  Y+  +  +N+ 
Sbjct: 1925 GHSGDTPTTGYVIEARPSDEGLWDMFVKDIPRSATSYTLSLDKLRQGVTYEFRVVAVNEA 1984

Query: 1890 ARSSPVVIDASTAIDA 1905
                P   + STA+ A
Sbjct: 1985 GYGEP--SNPSTAVSA 1998



 Score =  117 bits (292), Expect = 2e-25
 Identities = 194/912 (21%), Positives = 338/912 (37%), Gaps = 129/912 (14%)

Query: 1138 IVVSGLTPGVEYVYTIQVLRD-GQERDAPIVNKVVTPLSPPT----NLHLEANPDTGVLT 1192
            + VSGLTP   Y + +  + + G+ + +   ++++ P  PP+    N+      +  ++ 
Sbjct: 728  VTVSGLTPARTYQFRVCAVNEVGRGQYSAETSRLMLPEEPPSAPPKNIVASGRTNQSIM- 786

Query: 1193 VSWERSTTPDITG--------YRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYN 1244
            V W+     +  G        YR+   P   QQ N    +   + + C   +L    +Y 
Sbjct: 787  VQWQPPPETEHNGVLRGYILRYRLAGLPGEYQQRN----ITSPEVNYCLVTDLIIWTQYE 842

Query: 1245 VSVYTVKDDKESV---PISDTIIPAVP--PPTDLRFTNIGPDTMRVTWAPPPSIDLTNFL 1299
            + V         V    +++  +  VP  PP +++   +   T++  W PPP   +    
Sbjct: 843  IQVAAYNGAGLGVFSRAVTEYTLQGVPTAPPQNVQTEAVNSTTIQFLWNPPPQQFINGIN 902

Query: 1300 VRYS----PVKNEEDVAELSISPSDNAVV---LTNLLPGTEYVVSVSSVYEQHESTPLRG 1352
              Y     P    E V  ++I+P  + V    +TNL   T Y  SV       +  P   
Sbjct: 903  QGYKLLAWPADAPEAVTVVTIAPDFHGVHHGHITNLKKFTAYFTSVLCFTTPGDGPPSTP 962

Query: 1353 RQK-TGLDSPTGI---DFSDITANSFTVHWIAP---RATITGYRIRHHPEHFSGRPREDR 1405
            +   T  D P  +    F++I   S  V W  P      ITGY+I        GR  + R
Sbjct: 963  QLVWTQEDKPGAVGHLSFTEILDTSLKVSWQEPLEKNGIITGYQISWE---VYGR-NDSR 1018

Query: 1406 VPHSRNSIT----LTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATP 1461
            + H+ NS T    +  L+  T Y + + A+        L+   +  S VP DL      P
Sbjct: 1019 LTHTLNSTTHEYKIQGLSSLTTYTIDVAAVTAVGTG--LVTSSTISSGVPPDLP---GAP 1073

Query: 1462 TSLLISWDAPAVTVRYYRITY------------GETGGNSPVQEFTVPGSKSTAT----- 1504
            ++L+IS  +P      +R  Y            G+ G     +E+     +         
Sbjct: 1074 SNLVISNISPRSATLQFRPGYDGKTSISRWIVEGQVGAIGDEEEWVTLYEEENEPDAQML 1133

Query: 1505 -ISGLKPGVDYTITVYAVTGRGDSP--ASSKPISINYRTEIDKPSQMQVTDVQDNSISVK 1561
             I  L P   Y   +  V   G SP   SS+ I          P+ + V    + S+ ++
Sbjct: 1134 EIPNLTPYTHYRFRMKQVNIVGPSPYSPSSRVIQTLQAPPDVAPTSVTVRTASETSLRLR 1193

Query: 1562 WLP-------SSSPVTGYRVTTTPKNGPGPTKTKTAGPD-QTEMTIEGLQPTVEYVVSVY 1613
            W+P        +    GYR+     +       +      + E TIE L+  +EY + + 
Sbjct: 1194 WVPLPDSQYNGNPESVGYRIKYWRSDLQSSAVAQVVSDRLEREFTIEELEEWMEYELQMQ 1253

Query: 1614 AQNP----------SGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYR 1663
            A N            G ++  V +A       + ++ T + +    +  +   G +  Y+
Sbjct: 1254 AFNAVGAGPWSEVVRGRTRESVPSAAPENVSAEAVSSTQILLTWTSVPEQDQNGLILGYK 1313

Query: 1664 VTYSSPEDGIHELFPAP------DGEEDTAELQGLRPGSEYTVSVVA---LHDDMESQPL 1714
            + + + +     L P P           +A L GLR    Y + V+A   + + + S PL
Sbjct: 1314 ILFRAKD-----LDPEPRSHIVRGNHTQSALLAGLRKFVLYELQVLAFTRIGNGVPSTPL 1368

Query: 1715 I--GTQSTAIPAPTDLKFTQVTPTSLSAQWTPP---NVQLTGYRVRVT-PKEKTGPMKEI 1768
            I   T+  A   P  L F +V  TS+   W PP   N  + GY++              +
Sbjct: 1369 ILERTKDDAPGPPVRLVFPEVRLTSVRIVWQPPEEPNGIILGYQIAYRLASSSPHTFTTV 1428

Query: 1769 NLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLEN---VSPPRRARVTDA 1825
             +         + L   + Y   + A        P +  V T E     +PPR   V  A
Sbjct: 1429 EVGATVRQFTATDLAPESAYIFRLSAKTRQGWGEPLEATVITTEKRERPAPPRELLVPQA 1488

Query: 1826 --TETTITISWRTKTETITGF-----QVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTD 1878
              T  ++ + W   ++  +       QV  +P         +I  +  +  +  L+P T 
Sbjct: 1489 EVTARSLRLQWVPGSDGASPIRYFTMQVRELPRGEWQTYSSSISHEATACVVDRLRPFTS 1548

Query: 1879 YKIYLYTLND------NARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPR----- 1927
            YK+ L   ND      ++ +  V        + P ++     T +S+L+ WQPPR     
Sbjct: 1549 YKLRLKATNDIGDSDFSSETEAVTTLQDVPGEPPGSVSATPHTTSSVLIQWQPPRDESLN 1608

Query: 1928 ARITGYIIKYEK 1939
              + GY I Y +
Sbjct: 1609 GLLQGYRIYYRE 1620



 Score =  102 bits (255), Expect = 3e-21
 Identities = 233/1097 (21%), Positives = 407/1097 (37%), Gaps = 171/1097 (15%)

Query: 1043 NVGPSVSKYPLRNLQPASEYTVSLVAIKG---NQESPKATGVFTTLQPGSSIPPYNTEV- 1098
            NVGP ++   +  L PA  Y   + A+      Q S + + +    +P S+ PP N    
Sbjct: 720  NVGPEMTGVTVSGLTPARTYQFRVCAVNEVGRGQYSAETSRLMLPEEPPSA-PPKNIVAS 778

Query: 1099 --TETTIVITWTPAPRI-------GFKLGVRPS--QGGEAPREVTS-DSGSIVVSGLTPG 1146
              T  +I++ W P P         G+ L  R +   G    R +TS +    +V+ L   
Sbjct: 779  GRTNQSIMVQWQPPPETEHNGVLRGYILRYRLAGLPGEYQQRNITSPEVNYCLVTDLIIW 838

Query: 1147 VEYVYTIQVLRDGQERDAPIVNKVVT-------PLSPPTNLHLEANPDTGVLTVSWERST 1199
             +Y   +            + ++ VT       P +PP N+  EA   T +  + W    
Sbjct: 839  TQYEIQVAAYNGA---GLGVFSRAVTEYTLQGVPTAPPQNVQTEAVNSTTIQFL-WNPPP 894

Query: 1200 TPDITG----YRITTTPTNGQQGNSLEEV------VHADQSSCTFDNLSPGLEYNVSVYT 1249
               I G    Y++   P +  +  ++  +      VH    +    NL     Y  SV  
Sbjct: 895  QQFINGINQGYKLLAWPADAPEAVTVVTIAPDFHGVHHGHIT----NLKKFTAYFTSVLC 950

Query: 1250 VKDDKESVPISDTIIPAVPPPTD----LRFTNIGPDTMRVTWAPPPSID--LTNFLVRYS 1303
                 +  P +  ++            L FT I   +++V+W  P   +  +T + + + 
Sbjct: 951  FTTPGDGPPSTPQLVWTQEDKPGAVGHLSFTEILDTSLKVSWQEPLEKNGIITGYQISWE 1010

Query: 1304 PVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLD---- 1359
                 +     +++ + +   +  L   T Y + V++V              +G+     
Sbjct: 1011 VYGRNDSRLTHTLNSTTHEYKIQGLSSLTTYTIDVAAVTAVGTGLVTSSTISSGVPPDLP 1070

Query: 1360 -SPTGIDFSDITANSFTVHW---IAPRATITGYRIRHH------PEHFSGRPREDRVPHS 1409
             +P+ +  S+I+  S T+ +      + +I+ + +          E +     E+  P +
Sbjct: 1071 GAPSNLVISNISPRSATLQFRPGYDGKTSISRWIVEGQVGAIGDEEEWVTLYEEENEPDA 1130

Query: 1410 RNSITLTNLTPGTEY-----VVSIVALNGREESPLLIGQQSTVSDV-PRDLEVVAATPTS 1463
            +  + + NLTP T Y      V+IV  +    S  +I       DV P  + V  A+ TS
Sbjct: 1131 Q-MLEIPNLTPYTHYRFRMKQVNIVGPSPYSPSSRVIQTLQAPPDVAPTSVTVRTASETS 1189

Query: 1464 LLISWDAPAVTVRY--------YRITYGETG-GNSPVQEFTVPGSKSTATISGLKPGVDY 1514
            L + W  P    +Y        YRI Y  +   +S V +      +   TI  L+  ++Y
Sbjct: 1190 LRLRW-VPLPDSQYNGNPESVGYRIKYWRSDLQSSAVAQVVSDRLEREFTIEELEEWMEY 1248

Query: 1515 TITVYAVTGRGDSPASSKPISINYRTEIDKPS----QMQVTDVQDNSISVKWLP-----S 1565
             + + A    G  P S     +  RT    PS     +    V    I + W        
Sbjct: 1249 ELQMQAFNAVGAGPWSEV---VRGRTRESVPSAAPENVSAEAVSSTQILLTWTSVPEQDQ 1305

Query: 1566 SSPVTGYRVTTTPKN-GPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQP- 1623
            +  + GY++    K+  P P      G       + GL+  V Y + V A    G   P 
Sbjct: 1306 NGLILGYKILFRAKDLDPEPRSHIVRGNHTQSALLAGLRKFVLYELQVLAFTRIGNGVPS 1365

Query: 1624 ----LVQTAVTNIDRPKGLAFTDVDVDSIKIAW---ESPQGQVSRYRVTYSSPEDGIHEL 1676
                L +T       P  L F +V + S++I W   E P G +  Y++ Y       H  
Sbjct: 1366 TPLILERTKDDAPGPPVRLVFPEVRLTSVRIVWQPPEEPNGIILGYQIAYRLASSSPHTF 1425

Query: 1677 FPAPDG---EEDTAELQGLRPGSEYTVSVVALHDDMESQPL----IGTQSTAIPAPTD-- 1727
                 G    + TA    L P S Y   + A       +PL    I T+    PAP    
Sbjct: 1426 TTVEVGATVRQFTAT--DLAPESAYIFRLSAKTRQGWGEPLEATVITTEKRERPAPPREL 1483

Query: 1728 -LKFTQVTPTSLSAQWTPPN-----VQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSG 1781
             +   +VT  SL  QW P +     ++    +VR  P+ +       +++ ++++ VV  
Sbjct: 1484 LVPQAEVTARSLRLQWVPGSDGASPIRYFTMQVRELPRGEWQTYSS-SISHEATACVVDR 1542

Query: 1782 LMVATKYEVSVYALKDTLTS--RPAQGVVTTLENV--SPPRRARVTDATETTITISWRTK 1837
            L   T Y++ + A  D   S        VTTL++V   PP     T  T +++ I W+  
Sbjct: 1543 LRPFTSYKLRLKATNDIGDSDFSSETEAVTTLQDVPGEPPGSVSATPHTTSSVLIQWQPP 1602

Query: 1838 TET-----ITGFQV-------------------DAVPANGQTPIQRTIKPDVRSYT---- 1869
             +      + G+++                   + +  + +   Q + K    S T    
Sbjct: 1603 RDESLNGLLQGYRIYYRELEYEAGSGTEAKTLKNPIALHAELTAQSSFKTVNSSSTSTMC 1662

Query: 1870 -ITGLQPGTDYKIYLYTLN---DNARSSPVVIDASTAIDA--PSNLRFLATTPNSLLVSW 1923
             +T L+    Y++ +   N   ++  S+PV +    A  A  P N++    T + L V+W
Sbjct: 1663 ELTHLKKYRRYEVIMTAYNIIGESPASAPVEVFVGEAAPAMAPQNVQVTPLTASQLEVTW 1722

Query: 1924 QPP-----RARITGYIIKYEKPGS----PPREVVPRPRPGVTEATITGLEPGTEYTIYVI 1974
             PP        I GY I Y +  S       +V+  P P V    +  L   T+Y + + 
Sbjct: 1723 DPPPPESQNGNIQGYKIYYWEADSQNETEKMKVLFLPEPVV---RLKNLTSHTKYLVSIS 1779

Query: 1975 ALK---NNQKSEPLIGR 1988
            A     +  KS+P  GR
Sbjct: 1780 AFNAAGDGPKSDPQQGR 1796



 Score = 77.0 bits (188), Expect = 2e-13
 Identities = 103/475 (21%), Positives = 184/475 (38%), Gaps = 52/475 (10%)

Query: 1513 DYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISV--KWL---PSSS 1567
            DY+  + +  G     A  + I + +      P  + V+    +S +V   W+     +S
Sbjct: 644  DYSCEIVSEGGNDSRMARLEVIELPH-----SPQNLLVSPNSSHSHAVVLSWVRPFDGNS 698

Query: 1568 PVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQT 1627
            P+  Y V  +  N P        GP+ T +T+ GL P   Y   V A N  G  Q   +T
Sbjct: 699  PILYYIVELSENNSPWKVHLSNVGPEMTGVTVSGLTPARTYQFRVCAVNEVGRGQYSAET 758

Query: 1628 AVTNIDR------PKGLAFTDVDVDSIKIAWESP---------QGQVSRYRVTYSSPEDG 1672
            +   +        PK +  +     SI + W+ P         +G + RYR+    P + 
Sbjct: 759  SRLMLPEEPPSAPPKNIVASGRTNQSIMVQWQPPPETEHNGVLRGYILRYRLA-GLPGEY 817

Query: 1673 IHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHD---DMESQPLIGTQSTAIPA--PTD 1727
                  +P  E +   +  L   ++Y + V A +     + S+ +       +P   P +
Sbjct: 818  QQRNITSP--EVNYCLVTDLIIWTQYEIQVAAYNGAGLGVFSRAVTEYTLQGVPTAPPQN 875

Query: 1728 LKFTQVTPTSLSAQWTPPNVQL-----TGYRVRVTPKEKTGPMKEINLAPDSSSV---VV 1779
            ++   V  T++   W PP  Q       GY++   P +    +  + +APD   V    +
Sbjct: 876  VQTEAVNSTTIQFLWNPPPQQFINGINQGYKLLAWPADAPEAVTVVTIAPDFHGVHHGHI 935

Query: 1780 SGLMVATKYEVSVYALKDTLTSRPA--QGVVTTLENVSPPRRARVTDATETTITISWR-- 1835
            + L   T Y  SV          P+  Q V T  +          T+  +T++ +SW+  
Sbjct: 936  TNLKKFTAYFTSVLCFTTPGDGPPSTPQLVWTQEDKPGAVGHLSFTEILDTSLKVSWQEP 995

Query: 1836 -TKTETITGFQVD-AVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSS 1893
              K   ITG+Q+   V     + +  T+      Y I GL   T Y I +  +   A  +
Sbjct: 996  LEKNGIITGYQISWEVYGRNDSRLTHTLNSTTHEYKIQGLSSLTTYTIDVAAV--TAVGT 1053

Query: 1894 PVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVV 1948
             +V  ++ +   P +   L   P++L++S   PR+    +   Y+   S  R +V
Sbjct: 1054 GLVTSSTISSGVPPD---LPGAPSNLVISNISPRSATLQFRPGYDGKTSISRWIV 1105



 Score = 74.3 bits (181), Expect = 1e-12
 Identities = 143/675 (21%), Positives = 244/675 (36%), Gaps = 109/675 (16%)

Query: 662  HLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPL 721
            H  S  + GL+  V+YE Q+++  + G+             STP+     T +  P  P+
Sbjct: 1334 HTQSALLAGLRKFVLYELQVLAFTRIGN----------GVPSTPLILER-TKDDAPGPPV 1382

Query: 722  VATSESVTEITASSFVVSWVSASD---TVSGFRVEYELSEEGDEP-QYLDLPSTATSVNI 777
                    E+  +S  + W    +    + G+++ Y L+         +++ +T      
Sbjct: 1383 RLV---FPEVRLTSVRIVWQPPEEPNGIILGYQIAYRLASSSPHTFTTVEVGATVRQFTA 1439

Query: 778  PDLLPGRKYIVNVYQISEDG----EQSLILSTSQTTAPDAPPDPTVDQVDDT--SIVVRW 831
             DL P   YI  +   +  G     ++ +++T +   P  P +  V Q + T  S+ ++W
Sbjct: 1440 TDLAPESAYIFRLSAKTRQGWGEPLEATVITTEKRERPAPPRELLVPQAEVTARSLRLQW 1499

Query: 832  ---SRPQAPITGY--RIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEE- 885
               S   +PI  +  ++   P  E  +   ++   A +  +  L+P   Y + + A  + 
Sbjct: 1500 VPGSDGASPIRYFTMQVRELPRGEWQTYSSSISHEATACVVDRLRPFTSYKLRLKATNDI 1559

Query: 886  -----NQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP-----ESAVT 935
                 + E+  V   Q+  G P      +P        T   V I W PP        + 
Sbjct: 1560 GDSDFSSETEAVTTLQDVPGEPPGSVSATPH-------TTSSVLIQWQPPRDESLNGLLQ 1612

Query: 936  GYRVDVIPVNLPGEHGQ-----RLPI------------------SRNTFAEVTGLSPGVT 972
            GYR+    +      G      + PI                  S +T  E+T L     
Sbjct: 1613 GYRIYYRELEYEAGSGTEAKTLKNPIALHAELTAQSSFKTVNSSSTSTMCELTHLKKYRR 1672

Query: 973  Y-----YFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP-----RA 1022
            Y      + +   S       +   +     AP N+Q    T S + V W PP       
Sbjct: 1673 YEVIMTAYNIIGESPASAPVEVFVGEAAPAMAPQNVQVTPLTASQLEVTWDPPPPESQNG 1732

Query: 1023 QITGYRLTV-GLTRRGQPRQYNV----GPSVSKYPLRNLQPASEYTVSLVAIKGNQESPK 1077
             I GY++       + +  +  V     P V    L+NL   ++Y VS+ A     + PK
Sbjct: 1733 NIQGYKIYYWEADSQNETEKMKVLFLPEPVVR---LKNLTSHTKYLVSISAFNAAGDGPK 1789

Query: 1078 A---TGVFTTLQPGSSIPPYNTEVTETTIVITW-TPAPRIGFKLGVRPSQGGEAPREVTS 1133
            +    G      PG+      +E+T TT+ ++W  PA   G   G R      AP +  S
Sbjct: 1790 SDPQQGRTHQAAPGAPSFLAFSEITSTTLNVSWGEPAAANGILQGYRVVYEPLAPVQGVS 1849

Query: 1134 DSGSIVVSG----------LTPGVEYVYTIQ--VLRDGQERDAPIVNKVVTPLSPPTNLH 1181
               ++ V G          LT GV Y + +Q   +  G E  A I        SP +   
Sbjct: 1850 KVVTVEVRGNWQRWLKVRDLTKGVTYFFRVQARTITYGPELQANITAGPAEG-SPGSPRD 1908

Query: 1182 LEANPDTGVLTVSWERSTTPD--ITGYRITTTPTNGQQGNSLEEVVHADQSSCT--FDNL 1237
            +        LT+ W    + D   TGY I   P++    +   + +    +S T   D L
Sbjct: 1909 VLVTKSASELTLQWTEGHSGDTPTTGYVIEARPSDEGLWDMFVKDIPRSATSYTLSLDKL 1968

Query: 1238 SPGLEYNVSVYTVKD 1252
              G+ Y   V  V +
Sbjct: 1969 RQGVTYEFRVVAVNE 1983



 Score = 33.5 bits (75), Expect = 2.5
 Identities = 23/82 (28%), Positives = 40/82 (48%), Gaps = 8/82 (9%)

Query: 1903 IDAPSNLRFLATTPNS-----LLVSWQPP---RARITGYIIKYEKPGSPPREVVPRPRPG 1954
            I+ P + + L  +PNS     +++SW  P    + I  YI++  +  SP +  +    P 
Sbjct: 665  IELPHSPQNLLVSPNSSHSHAVVLSWVRPFDGNSPILYYIVELSENNSPWKVHLSNVGPE 724

Query: 1955 VTEATITGLEPGTEYTIYVIAL 1976
            +T  T++GL P   Y   V A+
Sbjct: 725  MTGVTVSGLTPARTYQFRVCAV 746


>gi|18860892 protein tyrosine phosphatase, receptor type, D isoform 3
            precursor [Homo sapiens]
          Length = 1903

 Score =  149 bits (377), Expect = 2e-35
 Identities = 170/673 (25%), Positives = 286/673 (42%), Gaps = 81/673 (12%)

Query: 1367 SDITANSFTVHWIAPRAT-ITGYRIRHHPEHFSGRPRE-DRVPHSRNSITLTNLTPGTEY 1424
            ++ TA S T+ W +     ++ Y I+H P++     +E D V  +R S+    L+P ++Y
Sbjct: 332  TESTATSITLTWDSGNPEPVSYYIIQHKPKNSEELYKEIDGVATTRYSVA--GLSPYSDY 389

Query: 1425 VVSIVALN----GREESPLLIG-QQSTVSDVPRDLEVVAATPTSLLISW---DAPAVTVR 1476
               +VA+N    G    P+L    +   S  PRD++    + T++L+ W   + P   ++
Sbjct: 390  EFRVVAVNNIGRGPPSEPVLTQTSEQAPSSAPRDVQARMLSSTTILVQWKEPEEPNGQIQ 449

Query: 1477 YYRITY--GETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPI 1534
             YR+ Y    T   +   +  V  S+ T TI  L P   Y++ V A T  GD P SS   
Sbjct: 450  GYRVYYTMDPTQHVNNWMKHNVADSQIT-TIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQ 508

Query: 1535 SINYRTEIDKPSQMQVTDVQDNSISVKWL-PSSSPVTGYRVTTTPKNGPGPTKTKTAGPD 1593
             I       +P   +     + SI + W  P S  +  Y +    K+G    + +     
Sbjct: 509  VITQTGVPGQPLNFKAEPESETSILLSWTPPRSDTIANYELVY--KDGEHGEEQRITIEP 566

Query: 1594 QTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDR-----PKGLAFTDVDVDSI 1648
             T   ++GL+P   Y   + A++P G      + +   +       P+ ++ T     SI
Sbjct: 567  GTSYRLQGLKPNSLYYFRLAARSPQGLGASTAEISARTMQSKPSAPPQDISCTSPSSTSI 626

Query: 1649 KIAWESP-----QGQVSRYRVTYSS---PEDGIHELFPAPDGEEDTAE--LQGLRPGSEY 1698
             ++W+ P      G ++ Y + Y++    +D  HE+   P    DT +  L+ L   +EY
Sbjct: 627  LVSWQPPPVEKQNGIITEYSIKYTAVDGEDDKPHEILGIP---SDTTKYLLEQLEKWTEY 683

Query: 1699 TVSVVALHDDM----ESQPLIGTQSTAIPA--PTDLKFTQVTPTSLSAQWTPP-----NV 1747
             ++V A H D+    ES  ++   +  +P+  P  ++   V  TS+   W  P     + 
Sbjct: 684  RITVTA-HTDVGPGPESLSVLIRTNEDVPSGPPRKVEVEAVNSTSVKVSWRSPVPNKQHG 742

Query: 1748 QLTGYRVRVTPKEKTGP-----MKEINLAPDSSSVVVSGLMVATKYEVSVYALK---DTL 1799
            Q+ GY+V     E   P     +K++ LA D+  +++SGL   T Y ++V A     D  
Sbjct: 743  QIRGYQVHYVRMENGEPKGQPMLKDVMLA-DAQDMIISGLQPETSYSLTVTAYTTKGDGA 801

Query: 1800 TSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTET---ITGFQV-----DAVPA 1851
             S+P   +V+T   V    R  +      T  I W    +T   + G+++     D  P 
Sbjct: 802  RSKPK--LVSTTGAVPGKPRLVINHTQMNTALIQWHPPVDTFGPLQGYRLKFGRKDMEPL 859

Query: 1852 NGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPS---- 1907
               T ++ + K D   +T T +  G  Y   L   N       +V + S   + P+    
Sbjct: 860  ---TTLEFSEKED--HFTATDIHKGASYVFRLSARNKVGFGEEMVKEISIPEEVPTGFPQ 914

Query: 1908 NLRFLATTPNSLLVSWQPP-----RARITGYIIKYEKPGSPPREVVPRPRPGVTEATITG 1962
            NL    TT  S+ +SWQPP        IT Y + Y     P   +     P  T  T+TG
Sbjct: 915  NLHSEGTTSTSVQLSWQPPVLAERNGIITKYTLLYRDINIPLLPMEQLIVPADTTMTLTG 974

Query: 1963 LEPGTEYTIYVIA 1975
            L+P T Y + V A
Sbjct: 975  LKPDTTYDVKVRA 987



 Score =  135 bits (340), Expect = 5e-31
 Identities = 201/883 (22%), Positives = 348/883 (39%), Gaps = 117/883 (13%)

Query: 752  VEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAP 811
            ++ E SEE D+ +Y  + + +         P   Y+  + ++     +  I  T+    P
Sbjct: 192  LQIEQSEESDQGKYECVATNSAGTRYS--APANLYVRELREVRRVPPRFSIPPTNHEIMP 249

Query: 812  DAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQ 871
                + T   V      V+W                  E  + E ++P   N + L+D++
Sbjct: 250  GGSVNITCVAVGSPMPYVKWML--------------GAEDLTPEDDMPIGRNVLELNDVR 295

Query: 872  PGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFV-EVTDVKVTIMWTPP 930
                Y            ST  VI+     T ++  +P P     V E T   +T+ W   
Sbjct: 296  QSANYTCVAM-------STLGVIEAIAQITVKA--LPKPPGTPVVTESTATSITLTWDSG 346

Query: 931  ESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSH---GRESK 987
                  Y +         E  + +     T   V GLSP   Y F+V AV++   G  S+
Sbjct: 347  NPEPVSYYIIQHKPKNSEELYKEIDGVATTRYSVAGLSPYSDYEFRVVAVNNIGRGPPSE 406

Query: 988  PLTAQQTTKL--DAPTNLQFVNETDSTVLVRWTPPR---AQITGYRL--TVGLTRR-GQP 1039
            P+  Q + +    AP ++Q    + +T+LV+W  P     QI GYR+  T+  T+     
Sbjct: 407  PVLTQTSEQAPSSAPRDVQARMLSSTTILVQWKEPEEPNGQIQGYRVYYTMDPTQHVNNW 466

Query: 1040 RQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEV- 1098
             ++NV  S     + NL P   Y+V ++A     + P ++ +    Q G    P N +  
Sbjct: 467  MKHNVADSQIT-TIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVPGQPLNFKAE 525

Query: 1099 --TETTIVITWTPAPR----IGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYT 1152
              +ET+I+++WTP PR      ++L  +  + GE  R       S  + GL P   Y + 
Sbjct: 526  PESETSILLSWTP-PRSDTIANYELVYKDGEHGEEQRITIEPGTSYRLQGLKPNSLYYFR 584

Query: 1153 IQVLRDGQERDAPIVNKVVT-----PLSPPTNLHLEANPDTGVLTVSWERSTTPD----I 1203
            +   R  Q   A             P +PP ++   +   T +L VSW+          I
Sbjct: 585  LAA-RSPQGLGASTAEISARTMQSKPSAPPQDISCTSPSSTSIL-VSWQPPPVEKQNGII 642

Query: 1204 TGYRITTTPTNGQQGNSLEEV-VHADQSSCTFDNLSPGLEYNVSVYTVKD---DKESVPI 1259
            T Y I  T  +G+     E + + +D +    + L    EY ++V    D     ES+ +
Sbjct: 643  TEYSIKYTAVDGEDDKPHEILGIPSDTTKYLLEQLEKWTEYRITVTAHTDVGPGPESLSV 702

Query: 1260 SDTIIPAVP--PPTDLRFTNIGPDTMRVTW-APPPSID---LTNFLVRYSPVKNEEDVAE 1313
                   VP  PP  +    +   +++V+W +P P+     +  + V Y  ++N E   +
Sbjct: 703  LIRTNEDVPSGPPRKVEVEAVNSTSVKVSWRSPVPNKQHGQIRGYQVHYVRMENGEPKGQ 762

Query: 1314 LSISPSDNA----VVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTG------ 1363
              +     A    ++++ L P T Y ++V++   + +      R K  L S TG      
Sbjct: 763  PMLKDVMLADAQDMIISGLQPETSYSLTVTAYTTKGDGA----RSKPKLVSTTGAVPGKP 818

Query: 1364 -IDFSDITANSFTVHWIAPRAT---ITGYRIRHHPEHFSGRPREDRVP-------HSRNS 1412
             +  +    N+  + W  P  T   + GYR++          R+D  P          + 
Sbjct: 819  RLVINHTQMNTALIQWHPPVDTFGPLQGYRLKFG--------RKDMEPLTTLEFSEKEDH 870

Query: 1413 ITLTNLTPGTEYVVSIVALN----GREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISW 1468
             T T++  G  YV  + A N    G E    +   +   +  P++L     T TS+ +SW
Sbjct: 871  FTATDIHKGASYVFRLSARNKVGFGEEMVKEISIPEEVPTGFPQNLHSEGTTSTSVQLSW 930

Query: 1469 DAPAVTVRY-----YRITYGETG-GNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVT 1522
              P +  R      Y + Y +      P+++  VP   +T T++GLKP   Y + V A T
Sbjct: 931  QPPVLAERNGIITKYTLLYRDINIPLLPMEQLIVPAD-TTMTLTGLKPDTTYDVKVRAHT 989

Query: 1523 GRGDSPASSKPISINYRT-EIDK--PSQMQVTDVQDNSISVKW 1562
             +G  P S    S+ +RT  +D+       V  V   S+ + W
Sbjct: 990  SKGPGPYSP---SVQFRTLPVDQVFAKNFHVKAVMKTSVLLSW 1029



 Score =  131 bits (330), Expect = 7e-30
 Identities = 158/701 (22%), Positives = 294/701 (41%), Gaps = 72/701 (10%)

Query: 696  DFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSAS-DTVSGFRVEY 754
            ++T  + ST      +   T    P    +  VTE TA+S  ++W S + + VS + +++
Sbjct: 299  NYTCVAMSTLGVIEAIAQITVKALPKPPGTPVVTESTATSITLTWDSGNPEPVSYYIIQH 358

Query: 755  ELSEEGDEPQYLDLPSTATS-VNIPDLLPGRKYIVNVYQISEDG----EQSLILSTSQTT 809
            +   +  E  Y ++   AT+  ++  L P   Y   V  ++  G     + ++  TS+  
Sbjct: 359  K--PKNSEELYKEIDGVATTRYSVAGLSPYSDYEFRVVAVNNIGRGPPSEPVLTQTSEQA 416

Query: 810  APDAPPDPTVDQVDDTSIVVRWSRPQAP---ITGYRIVYS--PSVEGSSTELNLPETANS 864
               AP D     +  T+I+V+W  P+ P   I GYR+ Y+  P+   ++   +    +  
Sbjct: 417  PSSAPRDVQARMLSSTTILVQWKEPEEPNGQIQGYRVYYTMDPTQHVNNWMKHNVADSQI 476

Query: 865  VTLSDLQPGVQYNITIYA---VEENQESTPV-VIQQETTGTPRSDTVPSPRDLQFVEVTD 920
             T+ +L P   Y++ + A   + +   S+ + VI Q  TG P       P + +    ++
Sbjct: 477  TTIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQ--TGVP-----GQPLNFKAEPESE 529

Query: 921  VKVTIMWTPPES-AVTGYRVDVIPVNLPGEHG--QRLPISRNTFAEVTGLSPGVTYYFKV 977
              + + WTPP S  +  Y +    V   GEHG  QR+ I   T   + GL P   YYF++
Sbjct: 530  TSILLSWTPPRSDTIANYEL----VYKDGEHGEEQRITIEPGTSYRLQGLKPNSLYYFRL 585

Query: 978  FAVSH---GRESKPLTAQ--QTTKLDAPTNLQFVNETDSTVLVRWTPPRAQ-----ITGY 1027
             A S    G  +  ++A+  Q+     P ++   + + +++LV W PP  +     IT Y
Sbjct: 586  AARSPQGLGASTAEISARTMQSKPSAPPQDISCTSPSSTSILVSWQPPPVEKQNGIITEY 645

Query: 1028 --RLTVGLTRRGQPRQYNVGPS-VSKYPLRNLQPASEYTVSLVAIKGNQESPKATGV-FT 1083
              + T       +P +    PS  +KY L  L+  +EY +++ A       P++  V   
Sbjct: 646  SIKYTAVDGEDDKPHEILGIPSDTTKYLLEQLEKWTEYRITVTAHTDVGPGPESLSVLIR 705

Query: 1084 TLQPGSSIPPYNTE---VTETTIVITW-TPAPR------IGFKLGVRPSQGGEAPRE--- 1130
            T +   S PP   E   V  T++ ++W +P P        G+++     + GE   +   
Sbjct: 706  TNEDVPSGPPRKVEVEAVNSTSVKVSWRSPVPNKQHGQIRGYQVHYVRMENGEPKGQPML 765

Query: 1131 ---VTSDSGSIVVSGLTPGVEYVYTIQVLR---DGQERDAPIVNKVVTPLSPPTNLHLEA 1184
               + +D+  +++SGL P   Y  T+       DG      +V+        P  +    
Sbjct: 766  KDVMLADAQDMIISGLQPETSYSLTVTAYTTKGDGARSKPKLVSTTGAVPGKPRLVINHT 825

Query: 1185 NPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYN 1244
              +T ++       T   + GYR+     + +   +LE     D  + T  +      + 
Sbjct: 826  QMNTALIQWHPPVDTFGPLQGYRLKFGRKDMEPLTTLEFSEKEDHFTATDIHKGASYVFR 885

Query: 1245 VSVYTVKDDKESVPISDTIIPAVPP---PTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVR 1301
            +S        E + + +  IP   P   P +L        +++++W PP   +    + +
Sbjct: 886  LSARNKVGFGEEM-VKEISIPEEVPTGFPQNLHSEGTTSTSVQLSWQPPVLAERNGIITK 944

Query: 1302 YSPVKNEEDV----AELSISPSDNAVVLTNLLPGTEYVVSV 1338
            Y+ +  + ++     E  I P+D  + LT L P T Y V V
Sbjct: 945  YTLLYRDINIPLLPMEQLIVPADTTMTLTGLKPDTTYDVKV 985



 Score =  127 bits (318), Expect = 2e-28
 Identities = 187/844 (22%), Positives = 323/844 (38%), Gaps = 89/844 (10%)

Query: 991  AQQTTK-LDAPTNLQFVNETDST-VLVRWTPPRAQITGYRLTVGLTRRGQPRQYNV-GPS 1047
            AQ T K L  P     V E+ +T + + W     +   Y +     +  +     + G +
Sbjct: 315  AQITVKALPKPPGTPVVTESTATSITLTWDSGNPEPVSYYIIQHKPKNSEELYKEIDGVA 374

Query: 1048 VSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFT-TLQPGSSIPPYNTE---VTETTI 1103
             ++Y +  L P S+Y   +VA+      P +  V T T +   S  P + +   ++ TTI
Sbjct: 375  TTRYSVAGLSPYSDYEFRVVAVNNIGRGPPSEPVLTQTSEQAPSSAPRDVQARMLSSTTI 434

Query: 1104 VITWT-PAPRIGFKLGVRPSQGGEAPREVTS-------DSGSIVVSGLTPGVEYVYTIQV 1155
            ++ W  P    G   G R     +  + V +       DS    +  L P  +  Y+++V
Sbjct: 435  LVQWKEPEEPNGQIQGYRVYYTMDPTQHVNNWMKHNVADSQITTIGNLVP--QKTYSVKV 492

Query: 1156 LRDGQERDAPIVN--KVVTPLS---PPTNLHLEANPDTGVLTVSWERSTTPDITGYRITT 1210
            L      D P+ +  +V+T       P N   E   +T +L +SW    +  I  Y +  
Sbjct: 493  LAFTSIGDGPLSSDIQVITQTGVPGQPLNFKAEPESETSIL-LSWTPPRSDTIANYELVY 551

Query: 1211 TPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDD---KESVPISDTIIPAV 1267
               +G+ G   + +     +S     L P   Y   +           +  IS   + + 
Sbjct: 552  K--DGEHGEE-QRITIEPGTSYRLQGLKPNSLYYFRLAARSPQGLGASTAEISARTMQSK 608

Query: 1268 P--PPTDLRFTNIGPDTMRVTWAPPPSID----LTNFLVRYSPVKNEEDVA-ELSISPSD 1320
            P  PP D+  T+    ++ V+W PPP       +T + ++Y+ V  E+D   E+   PSD
Sbjct: 609  PSAPPQDISCTSPSSTSILVSWQPPPVEKQNGIITEYSIKYTAVDGEDDKPHEILGIPSD 668

Query: 1321 NA-VVLTNLLPGTEYVVSVSSVYE-----QHESTPLRGRQKTGLDSPTGIDFSDITANSF 1374
                +L  L   TEY ++V++  +     +  S  +R  +      P  ++   + + S 
Sbjct: 669  TTKYLLEQLEKWTEYRITVTAHTDVGPGPESLSVLIRTNEDVPSGPPRKVEVEAVNSTSV 728

Query: 1375 TVHWIAP-----RATITGYRIRHHPEHFSGRPR-----EDRVPHSRNSITLTNLTPGTEY 1424
             V W +P        I GY++ H+    +G P+     +D +      + ++ L P T Y
Sbjct: 729  KVSWRSPVPNKQHGQIRGYQV-HYVRMENGEPKGQPMLKDVMLADAQDMIISGLQPETSY 787

Query: 1425 VVSIVAL----NGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVT---VRY 1477
             +++ A     +G    P L+     V   PR L +      + LI W  P  T   ++ 
Sbjct: 788  SLTVTAYTTKGDGARSKPKLVSTTGAVPGKPR-LVINHTQMNTALIQWHPPVDTFGPLQG 846

Query: 1478 YRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISIN 1537
            YR+ +G      P+        +   T + +  G  Y   + A    G      K ISI 
Sbjct: 847  YRLKFGRKD-MEPLTTLEFSEKEDHFTATDIHKGASYVFRLSARNKVGFGEEMVKEISIP 905

Query: 1538 YRTEIDKPSQMQVTDVQDNSISVKWLPS-----SSPVTGYRVTTTPKNGPGPTKTKTAGP 1592
                   P  +        S+ + W P      +  +T Y +     N P     +   P
Sbjct: 906  EEVPTGFPQNLHSEGTTSTSVQLSWQPPVLAERNGIITKYTLLYRDINIPLLPMEQLIVP 965

Query: 1593 DQTEMTIEGLQPTVEYVVSVYAQNPSGES--QPLVQTAVTNIDR--PKGLAFTDVDVDSI 1648
              T MT+ GL+P   Y V V A    G     P VQ     +D+   K      V   S+
Sbjct: 966  ADTTMTLTGLKPDTTYDVKVRAHTSKGPGPYSPSVQFRTLPVDQVFAKNFHVKAVMKTSV 1025

Query: 1649 KIAWESPQGQVSR--YRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALH 1706
             ++WE P+   S   +++ Y   +DG  ++    DG      +  L+P   Y+     L 
Sbjct: 1026 LLSWEIPENYNSAMPFKILY---DDG--KMVEEVDGRATQKLIVNLKPEKSYS---FVLT 1077

Query: 1707 DDMESQPLIGTQSTAIPAPTDL--KFTQVTPTSLSAQWT------PPNVQLTGYRVRVTP 1758
            +   S   +  + TA  AP  L  K   +  T+L    T      P N  + GY + + P
Sbjct: 1078 NRGNSAGGLQHRVTAKTAPDVLRTKPAFIGKTNLDGMITVQLPEVPANENIKGYYIIIVP 1137

Query: 1759 KEKT 1762
             +K+
Sbjct: 1138 LKKS 1141



 Score =  105 bits (263), Expect = 4e-22
 Identities = 156/688 (22%), Positives = 258/688 (37%), Gaps = 93/688 (13%)

Query: 619  TPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNS-YTIKGLKPGVVY 677
            T S   S  + W++  P  +S YI++ +PKNS   +KE  I G   + Y++ GL P   Y
Sbjct: 332  TESTATSITLTWDSGNPEPVSYYIIQHKPKNSEELYKE--IDGVATTRYSVAGLSPYSDY 389

Query: 678  EGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFV 737
            E +++++   G              S PV   T T E  P S           +++++ +
Sbjct: 390  EFRVVAVNNIGR----------GPPSEPVL--TQTSEQAPSS--APRDVQARMLSSTTIL 435

Query: 738  VSWVSASD---TVSGFRVEYELSEEGDEPQYLDLPSTATSV-NIPDLLPGRKYIVNVYQI 793
            V W    +    + G+RV Y +        ++      + +  I +L+P + Y V V   
Sbjct: 436  VQWKEPEEPNGQIQGYRVYYTMDPTQHVNNWMKHNVADSQITTIGNLVPQKTYSVKVLAF 495

Query: 794  SEDGEQSL---ILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQA-PITGYRIVYSPSV 849
            +  G+  L   I   +QT  P  P +   +   +TSI++ W+ P++  I  Y +VY    
Sbjct: 496  TSIGDGPLSSDIQVITQTGVPGQPLNFKAEPESETSILLSWTPPRSDTIANYELVYKDGE 555

Query: 850  EGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPS 909
             G    + + E   S  L  L+P   Y   + A   + +       + +  T +S     
Sbjct: 556  HGEEQRITI-EPGTSYRLQGLKPNSLYYFRLAA--RSPQGLGASTAEISARTMQSKPSAP 612

Query: 910  PRDLQFVEVTDVKVTIMWTPP-----ESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEV 964
            P+D+     +   + + W PP        +T Y +    V+  GE  +          E+
Sbjct: 613  PQDISCTSPSSTSILVSWQPPPVEKQNGIITEYSIKYTAVD--GEDDKP--------HEI 662

Query: 965  TGLSPGVTYY----------FKVFAVSH---GRESKPLTAQQTTKLDAPT------NLQF 1005
             G+    T Y          +++   +H   G   + L+    T  D P+       ++ 
Sbjct: 663  LGIPSDTTKYLLEQLEKWTEYRITVTAHTDVGPGPESLSVLIRTNEDVPSGPPRKVEVEA 722

Query: 1006 VNETDSTVLVRWTPP-----RAQITGYRLTVGLTRRGQPRQYNVGPSV-----SKYPLRN 1055
            VN T  +V V W  P       QI GY++       G+P+   +   V         +  
Sbjct: 723  VNST--SVKVSWRSPVPNKQHGQIRGYQVHYVRMENGEPKGQPMLKDVMLADAQDMIISG 780

Query: 1056 LQPASEY--TVSLVAIKGNQESPKATGVFTT-LQPGSSIPPYNTEVTETTIVITWTP--- 1109
            LQP + Y  TV+    KG+    K   V TT   PG      N      T +I W P   
Sbjct: 781  LQPETSYSLTVTAYTTKGDGARSKPKLVSTTGAVPGKPRLVIN-HTQMNTALIQWHPPVD 839

Query: 1110 --APRIGFKLGV-RPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRD---GQERD 1163
               P  G++L   R         E +        + +  G  YV+ +        G+E  
Sbjct: 840  TFGPLQGYRLKFGRKDMEPLTTLEFSEKEDHFTATDIHKGASYVFRLSARNKVGFGEEMV 899

Query: 1164 APIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPD----ITGYRITTTPTNGQQGN 1219
              I      P   P NLH E    T V  +SW+     +    IT Y +     N     
Sbjct: 900  KEISIPEEVPTGFPQNLHSEGTTSTSV-QLSWQPPVLAERNGIITKYTLLYRDINIPLLP 958

Query: 1220 SLEEVVHADQSSCTFDNLSPGLEYNVSV 1247
              + +V AD ++ T   L P   Y+V V
Sbjct: 959  MEQLIVPAD-TTMTLTGLKPDTTYDVKV 985



 Score = 61.6 bits (148), Expect = 9e-09
 Identities = 86/394 (21%), Positives = 154/394 (39%), Gaps = 72/394 (18%)

Query: 1798 TLTSRPAQGVVTTLENVS------PPRRARVTDATETTITISWRT-KTETITGFQVDAVP 1850
            T  +    GV+  +  ++      PP    VT++T T+IT++W +   E ++ + +   P
Sbjct: 301  TCVAMSTLGVIEAIAQITVKALPKPPGTPVVTESTATSITLTWDSGNPEPVSYYIIQHKP 360

Query: 1851 ANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNAR---SSPVVIDAS--TAIDA 1905
             N +   +         Y++ GL P +DY+  +  +N+  R   S PV+   S      A
Sbjct: 361  KNSEELYKEIDGVATTRYSVAGLSPYSDYEFRVVAVNNIGRGPPSEPVLTQTSEQAPSSA 420

Query: 1906 PSNLRFLATTPNSLLVSW---QPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATIT- 1961
            P +++    +  ++LV W   + P  +I GY + Y     P + V    +  V ++ IT 
Sbjct: 421  PRDVQARMLSSTTILVQWKEPEEPNGQIQGYRVYYTM--DPTQHVNNWMKHNVADSQITT 478

Query: 1962 --GLEPGTEYTIYVIAL----------------KNNQKSEPLIGRKKTVQKTPFV---TH 2000
               L P   Y++ V+A                 +     +PL  + +   +T  +   T 
Sbjct: 479  IGNLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVPGQPLNFKAEPESETSILLSWTP 538

Query: 2001 PGYDTGNGIQL----------------PGTSGQQPSVGQQMIF-------EEHGFRRTTP 2037
            P  DT    +L                PGTS +   +    ++          G   +T 
Sbjct: 539  PRSDTIANYELVYKDGEHGEEQRITIEPGTSYRLQGLKPNSLYYFRLAARSPQGLGASTA 598

Query: 2038 PTTATPIRHRPRPYPPNVGQEALSQTTI--SWAP------FQDTSEYIISCHPV-GTDEE 2088
              +A  ++ +P   P ++   + S T+I  SW P          +EY I    V G D++
Sbjct: 599  EISARTMQSKPSAPPQDISCTSPSSTSILVSWQPPPVEKQNGIITEYSIKYTAVDGEDDK 658

Query: 2089 PLQ-FRVPGTSTSATLTGLTRGATYNIIVEALKD 2121
            P +   +P  +T   L  L +   Y I V A  D
Sbjct: 659  PHEILGIPSDTTKYLLEQLEKWTEYRITVTAHTD 692


>gi|20665034 tenascin XB isoform 2 [Homo sapiens]
          Length = 673

 Score =  148 bits (373), Expect = 7e-35
 Identities = 118/479 (24%), Positives = 203/479 (42%), Gaps = 31/479 (6%)

Query: 1560 VKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSG 1619
            + W  +  P   + V     NG  P      G DQ+++ I GL+P+  Y   +Y  +   
Sbjct: 3    LSWSVAQGPFDSFVVQYEDTNGQ-PQALLVDG-DQSKILISGLEPSTPYRFLLYGLHEGK 60

Query: 1620 ESQPLVQTAVTNI---------DRPK--GLAFTDVDVDSIKIAWESPQGQVSRYRVTYSS 1668
               PL     T +          RP+   L+ TDV   S+++ WE+P G    + + +  
Sbjct: 61   RLGPLSAEGTTGLAPAGQTSEESRPRLSQLSVTDVTTSSLRLNWEAPPGAFDSFLLRFGV 120

Query: 1669 PEDGIHELFPAP--------DGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQST 1720
            P     E  P P         G   +A L+ LR G+ Y++++  L    ++  + GT  T
Sbjct: 121  PSPSTLEPHPRPLLQRELMVPGTRHSAVLRDLRSGTLYSLTLYGLRGPHKADSIQGTART 180

Query: 1721 AIP---APTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSV 1777
              P   +P DL+F+++  TS    W PP  +   ++V     +   P + + +   + + 
Sbjct: 181  LSPVLESPRDLQFSEIRETSAKVNWMPPPSRADSFKVSYQLADGGEP-QSVQVDGQARTQ 239

Query: 1778 VVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTK 1837
             + GL+   +YEV+V +++    S P  G +TT+ +   P + R  + TE    + W+  
Sbjct: 240  KLQGLIPGARYEVTVVSVRGFEESEPLTGFLTTVPD--GPTQLRALNLTEGFAVLHWKPP 297

Query: 1838 TETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVI 1897
               +  + V  V A G  P+Q         Y +  L   T+Y   +  L     +SP  I
Sbjct: 298  QNPVDTYDVQ-VTAPGAPPLQAETPGSAVDYPLHDLVLHTNYTATVRGLRGPNLTSPASI 356

Query: 1898 DASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTE 1957
              +T ++AP +L     TP + L++W  P  R  GY++ +  PG   +E++     G+T 
Sbjct: 357  TFTTGLEAPRDLEAKEVTPRTALLTWTEPPVRPAGYLLSFHTPGGQNQEIL--LPGGITS 414

Query: 1958 ATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKT-VQKTPFVTHPGYDTGNGIQLPGTS 2015
              + GL P T Y   + A+       P+     T   + PF    G +  NG     TS
Sbjct: 415  HQLLGLFPSTSYNARLQAMWGQSLLPPVSTSFTTGGLRIPFPRDCGEEMQNGAGASRTS 473



 Score =  119 bits (299), Expect = 3e-26
 Identities = 108/440 (24%), Positives = 181/440 (41%), Gaps = 36/440 (8%)

Query: 1191 LTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTV 1250
            + +SW  +  P    + +    TNGQ    L   V  DQS      L P   Y   +Y +
Sbjct: 1    MRLSWSVAQGP-FDSFVVQYEDTNGQPQALL---VDGDQSKILISGLEPSTPYRFLLYGL 56

Query: 1251 KDDKESVPIS-----------DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFL 1299
             + K   P+S            T   + P  + L  T++   ++R+ W  PP     +FL
Sbjct: 57   HEGKRLGPLSAEGTTGLAPAGQTSEESRPRLSQLSVTDVTTSSLRLNWEAPPGA-FDSFL 115

Query: 1300 VRY---SPVKNEEDVA-----ELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLR 1351
            +R+   SP   E         EL +  + ++ VL +L  GT Y +++  +   H++  ++
Sbjct: 116  LRFGVPSPSTLEPHPRPLLQRELMVPGTRHSAVLRDLRSGTLYSLTLYGLRGPHKADSIQ 175

Query: 1352 GRQKT---GLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPH 1408
            G  +T    L+SP  + FS+I   S  V+W+ P +    +++ +      G P+  +V  
Sbjct: 176  GTARTLSPVLESPRDLQFSEIRETSAKVNWMPPPSRADSFKVSYQLAD-GGEPQSVQVDG 234

Query: 1409 SRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISW 1468
               +  L  L PG  Y V++V++ G EES  L G  +TV D P  L  +  T    ++ W
Sbjct: 235  QARTQKLQGLIPGARYEVTVVSVRGFEESEPLTGFLTTVPDGPTQLRALNLTEGFAVLHW 294

Query: 1469 DAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSP 1528
              P   V  Y +    T   +P  +   PGS     +  L    +YT TV  + G    P
Sbjct: 295  KPPQNPVDTYDVQV--TAPGAPPLQAETPGSAVDYPLHDLVLHTNYTATVRGLRG----P 348

Query: 1529 ASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTK 1588
              + P SI + T ++ P  ++  +V   +  + W        GY ++     G       
Sbjct: 349  NLTSPASITFTTGLEAPRDLEAKEVTPRTALLTWTEPPVRPAGYLLSFHTPGGQNQEILL 408

Query: 1589 TAGPDQTEMTIEGLQPTVEY 1608
              G   T   + GL P+  Y
Sbjct: 409  PGG--ITSHQLLGLFPSTSY 426



 Score =  117 bits (294), Expect = 1e-25
 Identities = 115/480 (23%), Positives = 197/480 (41%), Gaps = 57/480 (11%)

Query: 628  IQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQY 687
            + W+  Q      +++++   N  G+ +   + G  +   I GL+P   Y   L     Y
Sbjct: 3    LSWSVAQ-GPFDSFVVQYEDTN--GQPQALLVDGDQSKILISGLEPSTPYRFLL-----Y 54

Query: 688  GHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTV 747
            G  E  R    +   +T +      G+T+  S    +  SVT++T SS  ++W +     
Sbjct: 55   GLHEGKRLGPLSAEGTTGLAP---AGQTSEESRPRLSQLSVTDVTTSSLRLNWEAPPGAF 111

Query: 748  SGFRVEYELSEEGD-EP-------QYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQ 799
              F + + +      EP       + L +P T  S  + DL  G  Y + +Y +    + 
Sbjct: 112  DSFLLRFGVPSPSTLEPHPRPLLQRELMVPGTRHSAVLRDLRSGTLYSLTLYGLRGPHKA 171

Query: 800  SLILSTSQTTAP--DAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELN 857
              I  T++T +P  ++P D    ++ +TS  V W  P +    +++ Y  +  G    + 
Sbjct: 172  DSIQGTARTLSPVLESPRDLQFSEIRETSAKVNWMPPPSRADSFKVSYQLADGGEPQSVQ 231

Query: 858  LPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVP-SPRDLQFV 916
            +   A +  L  L PG +Y +T+ +V   +ES P+        T    TVP  P  L+ +
Sbjct: 232  VDGQARTQKLQGLIPGARYEVTVVSVRGFEESEPL--------TGFLTTVPDGPTQLRAL 283

Query: 917  EVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQR-----------LPISRNTFAEVT 965
             +T+    + W PP++ V  Y V V     P    +            L +  N  A V 
Sbjct: 284  NLTEGFAVLHWKPPQNPVDTYDVQVTAPGAPPLQAETPGSAVDYPLHDLVLHTNYTATVR 343

Query: 966  GL-SPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQI 1024
            GL  P +T               P +   TT L+AP +L+    T  T L+ WT P  + 
Sbjct: 344  GLRGPNLT--------------SPASITFTTGLEAPRDLEAKEVTPRTALLTWTEPPVRP 389

Query: 1025 TGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTT 1084
             GY L+   T  GQ ++  +   ++ + L  L P++ Y   L A+ G    P  +  FTT
Sbjct: 390  AGYLLSFH-TPGGQNQEILLPGGITSHQLLGLFPSTSYNARLQAMWGQSLLPPVSTSFTT 448



 Score =  106 bits (264), Expect = 3e-22
 Identities = 83/358 (23%), Positives = 143/358 (39%), Gaps = 26/358 (7%)

Query: 1648 IKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHD 1707
            ++++W   QG    + V Y         L    DG++    + GL P + Y   +  LH+
Sbjct: 1    MRLSWSVAQGPFDSFVVQYEDTNGQPQALLV--DGDQSKILISGLEPSTPYRFLLYGLHE 58

Query: 1708 DMESQPLIGTQSTAI-----------PAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVR- 1755
                 PL    +T +           P  + L  T VT +SL   W  P      + +R 
Sbjct: 59   GKRLGPLSAEGTTGLAPAGQTSEESRPRLSQLSVTDVTTSSLRLNWEAPPGAFDSFLLRF 118

Query: 1756 -------VTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVV 1808
                   + P  +    +E+ +     S V+  L   T Y +++Y L+    +   QG  
Sbjct: 119  GVPSPSTLEPHPRPLLQRELMVPGTRHSAVLRDLRSGTLYSLTLYGLRGPHKADSIQGTA 178

Query: 1809 TTLENV-SPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRS 1867
             TL  V   PR  + ++  ET+  ++W         F+V    A+G  P    +    R+
Sbjct: 179  RTLSPVLESPRDLQFSEIRETSAKVNWMPPPSRADSFKVSYQLADGGEPQSVQVDGQART 238

Query: 1868 YTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPR 1927
              + GL PG  Y++ + ++     S P+    +T  D P+ LR L  T    ++ W+PP+
Sbjct: 239  QKLQGLIPGARYEVTVVSVRGFEESEPLTGFLTTVPDGPTQLRALNLTEGFAVLHWKPPQ 298

Query: 1928 ARITGYIIKYEKPGSPPREVVPRPRPG-VTEATITGLEPGTEYTIYVIALKNNQKSEP 1984
              +  Y ++   PG+PP +      PG   +  +  L   T YT  V  L+    + P
Sbjct: 299  NPVDTYDVQVTAPGAPPLQA---ETPGSAVDYPLHDLVLHTNYTATVRGLRGPNLTSP 353



 Score = 96.7 bits (239), Expect = 2e-19
 Identities = 108/467 (23%), Positives = 188/467 (40%), Gaps = 38/467 (8%)

Query: 831  WSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQEST 890
            WS  Q P   + + Y  +  G    L +    + + +S L+P   Y   +Y + E +   
Sbjct: 5    WSVAQGPFDSFVVQYEDT-NGQPQALLVDGDQSKILISGLEPSTPYRFLLYGLHEGKRLG 63

Query: 891  PVVIQQETTGTPRSDTVPSPR----DLQFVEVTDVKVTIMWTPPESAVTGY--RVDVIPV 944
            P+  +  T   P   T    R     L   +VT   + + W  P  A   +  R  V   
Sbjct: 64   PLSAEGTTGLAPAGQTSEESRPRLSQLSVTDVTTSSLRLNWEAPPGAFDSFLLRFGVPSP 123

Query: 945  NLPGEHGQRL-------PISRNTFAEVTGLSPGVTYYFKVFAVS--HGRESKPLTAQQTT 995
            +    H + L       P +R++ A +  L  G  Y   ++ +   H  +S   TA+  +
Sbjct: 124  STLEPHPRPLLQRELMVPGTRHS-AVLRDLRSGTLYSLTLYGLRGPHKADSIQGTARTLS 182

Query: 996  K-LDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLR 1054
              L++P +LQF    +++  V W PP ++   ++++  L   G+P+   V        L+
Sbjct: 183  PVLESPRDLQFSEIRETSAKVNWMPPPSRADSFKVSYQLADGGEPQSVQVDGQARTQKLQ 242

Query: 1055 NLQPASEYTVSLVAIKGNQESPKATGVFTTLQPG-SSIPPYNTEVTETTIVITWTPAPRI 1113
             L P + Y V++V+++G +ES   TG  TT+  G + +   N  +TE   V+ W P    
Sbjct: 243  GLIPGARYEVTVVSVRGFEESEPLTGFLTTVPDGPTQLRALN--LTEGFAVLHWKPPQNP 300

Query: 1114 GFKLGVRPSQGGEAPREVTSDSGSI--VVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVV 1171
                 V+ +  G  P +  +   ++   +  L     Y  T++ LR G    +P      
Sbjct: 301  VDTYDVQVTAPGAPPLQAETPGSAVDYPLHDLVLHTNYTATVRGLR-GPNLTSPASITFT 359

Query: 1172 TPLSPPTNLHL-EANPDTGVLTVSWERSTTPDI--TGYRITTTPTNGQQGNSLEEVVHAD 1228
            T L  P +L   E  P T +LT  W   T P +   GY ++     GQ   + E ++   
Sbjct: 360  TGLEAPRDLEAKEVTPRTALLT--W---TEPPVRPAGYLLSFHTPGGQ---NQEILLPGG 411

Query: 1229 QSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPA---VPPPTD 1272
             +S     L P   YN  +  +       P+S +       +P P D
Sbjct: 412  ITSHQLLGLFPSTSYNARLQAMWGQSLLPPVSTSFTTGGLRIPFPRD 458


>gi|109633041 protein tyrosine phosphatase, receptor type, F isoform 1
            precursor [Homo sapiens]
          Length = 1907

 Score =  147 bits (371), Expect = 1e-34
 Identities = 173/640 (27%), Positives = 262/640 (40%), Gaps = 80/640 (12%)

Query: 1402 REDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPR---DLEVVA 1458
            +ED +P  RN + L+N+     Y    ++  G  E+      Q TV  +P+   DL V  
Sbjct: 274  KEDEMPVGRNVLELSNVVRSANYTCVAISSLGMIEATA----QVTVKALPKPPIDLVVTE 329

Query: 1459 ATPTSLLISWDAP-AVTVRYYRITYGETGGNSPVQEFTVPGSKSTA-TISGLKPGVDYTI 1516
             T TS+ ++WD+  +  V YY I Y   G   P QE  V G  +T  +I GL P  +Y  
Sbjct: 330  TTATSVTLTWDSGNSEPVTYYGIQYRAAGTEGPFQE--VDGVATTRYSIGGLSPFSEYAF 387

Query: 1517 TVYAVTGRGDSPASSKPISINYRTEIDKPS----QMQVTDVQDNSISVKWLPSSSP---V 1569
             V AV   G  P S    ++  RT    PS    ++Q   +  +++ V+W P   P   V
Sbjct: 388  RVLAVNSIGRGPPSE---AVRARTGEQAPSSPPRRVQARMLSASTMLVQWEPPEEPNGLV 444

Query: 1570 TGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEG-LQPTVEYVVSVYAQNPSGESQPLVQTA 1628
             GYRV  TP +   P        D   +T  G L P + Y + V A    G+  P     
Sbjct: 445  RGYRVYYTPDSRRPPNAWHKHNTDAGLLTTVGSLLPGITYSLRVLAFTAVGDGPPSPTIQ 504

Query: 1629 V-TNIDRPKGLAFTDVDVDS---IKIAWE-SPQGQVSRYRVTY--SSPEDGIHELFPAPD 1681
            V T    P   A    +V+S   I+++W   PQ ++  Y + Y  +  ED  H++   P 
Sbjct: 505  VKTQQGVPAQPADFQAEVESDTRIQLSWLLPPQERIIMYELVYWAAEDEDQQHKVTFDPT 564

Query: 1682 GEEDTAELQGLRPGSEYTVSVVALHD--------DMESQPLIGTQSTAIPAPTDLKFTQV 1733
                +  L+ L+P + Y   + A  D         +E++     QST    P  +    +
Sbjct: 565  S---SYTLEDLKPDTLYRFQLAARSDMGVGVFTPTIEART---AQSTPSAPPQKVMCVSM 618

Query: 1734 TPTSLSAQWTPP-----NVQLTGYRV--RVTPKEKTGPMKEINLAPDSSSVVVSGLMVAT 1786
              T++   W PP     N  +T Y V       E  G      ++ + SS  + GL   T
Sbjct: 619  GSTTVRVSWVPPPADSRNGVITQYSVAYEAVDGEDRGRHVVDGISREHSSWDLVGLEKWT 678

Query: 1787 KYEVSVYALKDTLTSRPAQGV-VTTLENV--SPPRRARVTDATETTITISWRTKTET--- 1840
            +Y V V A  D      +  V V T E+V   PPR+  V     T + + W+    +   
Sbjct: 679  EYRVWVRAHTDVGPGPESSPVLVRTDEDVPSGPPRKVEVEPLNSTAVHVYWKLPVPSKQH 738

Query: 1841 --ITGFQVDAVPANGQTPIQRTIKPDVR--------------SYTITGLQPGTDYKIYLY 1884
              I G+QV  V      P    I  DV                 TI+GL P T Y + + 
Sbjct: 739  GQIRGYQVTYVRLENGEPRGLPIIQDVMLAEAQWRPEESEDYETTISGLTPETTYSVTVA 798

Query: 1885 ---TLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPR---ARITGYIIKYE 1938
               T  D ARS P ++  + A+     +    T  N+ L+ W PP+     + GY ++Y 
Sbjct: 799  AYTTKGDGARSKPKIVTTTGAVPGRPTMMISTTAMNTALLQWHPPKELPGELLGYRLQYC 858

Query: 1939 KPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKN 1978
            +        +   +      T+TGL  GT Y I+ +A KN
Sbjct: 859  RADEARPNTIDFGKDD-QHFTVTGLHKGTTY-IFRLAAKN 896



 Score =  140 bits (354), Expect = 1e-32
 Identities = 169/731 (23%), Positives = 290/731 (39%), Gaps = 78/731 (10%)

Query: 1264 IPAVP-PPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNA 1322
            + A+P PP DL  T     ++ +TW    S  +T + ++Y     E    E+    +   
Sbjct: 315  VKALPKPPIDLVVTETTATSVTLTWDSGNSEPVTYYGIQYRAAGTEGPFQEVD-GVATTR 373

Query: 1323 VVLTNLLPGTEYVVSVSSVYEQHESTPLRG-RQKTGLDSPTG----IDFSDITANSFTVH 1377
              +  L P +EY   V +V       P    R +TG  +P+     +    ++A++  V 
Sbjct: 374  YSIGGLSPFSEYAFRVLAVNSIGRGPPSEAVRARTGEQAPSSPPRRVQARMLSASTMLVQ 433

Query: 1378 WIAPR---ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLT---NLTPGTEYVVSIVAL 1431
            W  P      + GYR+ + P+  S RP      H+ ++  LT   +L PG  Y + ++A 
Sbjct: 434  WEPPEEPNGLVRGYRVYYTPD--SRRPPNAWHKHNTDAGLLTTVGSLLPGITYSLRVLAF 491

Query: 1432 NGREESP----LLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVT-VRYYRITYGETG 1486
                + P    + +  Q  V   P D +    + T + +SW  P    +  Y + Y    
Sbjct: 492  TAVGDGPPSPTIQVKTQQGVPAQPADFQAEVESDTRIQLSWLLPPQERIIMYELVYWAAE 551

Query: 1487 GNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPS 1546
                  + T   + S+ T+  LKP   Y    + +  R D        +I  RT    PS
Sbjct: 552  DEDQQHKVTFDPT-SSYTLEDLKPDTLYR---FQLAARSDMGVGVFTPTIEARTAQSTPS 607

Query: 1547 ----QMQVTDVQDNSISVKWLPSSSP-----VTGYRVTTTPKNGPGPTKTKTAG--PDQT 1595
                ++    +   ++ V W+P  +      +T Y V     +G    +    G   + +
Sbjct: 608  APPQKVMCVSMGSTTVRVSWVPPPADSRNGVITQYSVAYEAVDGEDRGRHVVDGISREHS 667

Query: 1596 EMTIEGLQPTVEYVVSVYAQN---PSGESQPLVQTAVTNIDR--PKGLAFTDVDVDSIKI 1650
               + GL+   EY V V A     P  ES P++     ++    P+ +    ++  ++ +
Sbjct: 668  SWDLVGLEKWTEYRVWVRAHTDVGPGPESSPVLVRTDEDVPSGPPRKVEVEPLNSTAVHV 727

Query: 1651 AWESP-----QGQVSRYRVTYSSPEDGIHELFPA------------PDGEED-TAELQGL 1692
             W+ P      GQ+  Y+VTY   E+G     P             P+  ED    + GL
Sbjct: 728  YWKLPVPSKQHGQIRGYQVTYVRLENGEPRGLPIIQDVMLAEAQWRPEESEDYETTISGL 787

Query: 1693 RPGSEYTVSVVALH---DDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNV-- 1747
             P + Y+V+V A     D   S+P I T + A+P    +  +     +   QW PP    
Sbjct: 788  TPETTYSVTVAAYTTKGDGARSKPKIVTTTGAVPGRPTMMISTTAMNTALLQWHPPKELP 847

Query: 1748 -QLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQG 1806
             +L GYR++    ++  P   I+   D     V+GL   T Y   + A          + 
Sbjct: 848  GELLGYRLQYCRADEARP-NTIDFGKDDQHFTVTGLHKGTTYIFRLAAKNRAGLGEEFEK 906

Query: 1807 VVTTLENVSP--PRRARVTDATETTITISW-----RTKTETITGFQVDAVPANGQTPIQR 1859
             + T E++    P+   VT  T +T  ++W       +   I  + V     N Q  +Q 
Sbjct: 907  EIRTPEDLPSGFPQNLHVTGLTTSTTELAWDPPVLAERNGRIISYTVVFRDINSQQELQN 966

Query: 1860 TIKPDVRSYTITGLQPGTDY--KIYLYTLNDNARSSPVVIDASTAIDA--PSNLRFLATT 1915
             I  D R +T+TGL+P T Y  K+  +T   +   SP +   +  ++     N R  A  
Sbjct: 967  -ITTDTR-FTLTGLKPDTTYDIKVRAWTSKGSGPLSPSIQSRTMPVEQVFAKNFRVAAAM 1024

Query: 1916 PNSLLVSWQPP 1926
              S+L+SW+ P
Sbjct: 1025 KTSVLLSWEVP 1035



 Score =  127 bits (320), Expect = 1e-28
 Identities = 178/740 (24%), Positives = 294/740 (39%), Gaps = 91/740 (12%)

Query: 1308 EEDVAELSISPSDNAVVLTNLLPGTEYV-VSVSSV--YEQHESTPLRGRQKTGLDSPTGI 1364
            EE   E  +    N + L+N++    Y  V++SS+   E      ++   K  +D    +
Sbjct: 270  EELTKEDEMPVGRNVLELSNVVRSANYTCVAISSLGMIEATAQVTVKALPKPPID----L 325

Query: 1365 DFSDITANSFTVHWIAPRAT-ITGYRIRHHPEHFSGRPRE-DRVPHSRNSITLTNLTPGT 1422
              ++ TA S T+ W +  +  +T Y I++      G  +E D V  +R SI    L+P +
Sbjct: 326  VVTETTATSVTLTWDSGNSEPVTYYGIQYRAAGTEGPFQEVDGVATTRYSIG--GLSPFS 383

Query: 1423 EYVVSIVALNGREESP------LLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVT-- 1474
            EY   ++A+N     P         G+Q+  S  PR ++    + +++L+ W+ P     
Sbjct: 384  EYAFRVLAVNSIGRGPPSEAVRARTGEQAP-SSPPRRVQARMLSASTMLVQWEPPEEPNG 442

Query: 1475 -VRYYRITYGETGGNSPV---QEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPAS 1530
             VR YR+ Y       P    +  T  G  +T  +  L PG+ Y++ V A T  GD P S
Sbjct: 443  LVRGYRVYYTPDSRRPPNAWHKHNTDAGLLTT--VGSLLPGITYSLRVLAFTAVGDGPPS 500

Query: 1531 SKPISINYRTEIDKPSQ---MQVTDVQDNSISVKWL-PSSSPVTGYRVTTTPKNGPGPTK 1586
                +I  +T+   P+Q    Q     D  I + WL P    +  Y +            
Sbjct: 501  P---TIQVKTQQGVPAQPADFQAEVESDTRIQLSWLLPPQERIIMYELVYWAAEDEDQQH 557

Query: 1587 TKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGES--QPLVQTAV---TNIDRPKGLAFT 1641
              T  P  +  T+E L+P   Y   + A++  G     P ++      T    P+ +   
Sbjct: 558  KVTFDPTSS-YTLEDLKPDTLYRFQLAARSDMGVGVFTPTIEARTAQSTPSAPPQKVMCV 616

Query: 1642 DVDVDSIKIAWESP-----QGQVSRYRVTYSSP--EDGIHELFPAPDGEEDTAELQGLRP 1694
             +   +++++W  P      G +++Y V Y +   ED    +      E  + +L GL  
Sbjct: 617  SMGSTTVRVSWVPPPADSRNGVITQYSVAYEAVDGEDRGRHVVDGISREHSSWDLVGLEK 676

Query: 1695 GSEYTVSVVALHDDM----ESQPLIGTQSTAIPA--PTDLKFTQVTPTSLSAQWTPP--- 1745
             +EY V V A H D+    ES P++      +P+  P  ++   +  T++   W  P   
Sbjct: 677  WTEYRVWVRA-HTDVGPGPESSPVLVRTDEDVPSGPPRKVEVEPLNSTAVHVYWKLPVPS 735

Query: 1746 --NVQLTGYRVRVTPKEKTGP----------MKEINLAPDSSS---VVVSGLMVATKYEV 1790
              + Q+ GY+V     E   P          + E    P+ S      +SGL   T Y V
Sbjct: 736  KQHGQIRGYQVTYVRLENGEPRGLPIIQDVMLAEAQWRPEESEDYETTISGLTPETTYSV 795

Query: 1791 SVYALK---DTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTET---ITGF 1844
            +V A     D   S+P   +VTT   V       ++     T  + W    E    + G+
Sbjct: 796  TVAAYTTKGDGARSKPK--IVTTTGAVPGRPTMMISTTAMNTALLQWHPPKELPGELLGY 853

Query: 1845 QVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAID 1904
            ++    A+   P       D + +T+TGL  GT Y   L   N          +  T  D
Sbjct: 854  RLQYCRADEARPNTIDFGKDDQHFTVTGLHKGTTYIFRLAAKNRAGLGEEFEKEIRTPED 913

Query: 1905 APS----NLRFLATTPNSLLVSWQPP-----RARITGYIIKYEKPGSPPREVVPRPRPGV 1955
             PS    NL     T ++  ++W PP       RI  Y + +    S   +   +     
Sbjct: 914  LPSGFPQNLHVTGLTTSTTELAWDPPVLAERNGRIISYTVVFRDINS---QQELQNITTD 970

Query: 1956 TEATITGLEPGTEYTIYVIA 1975
            T  T+TGL+P T Y I V A
Sbjct: 971  TRFTLTGLKPDTTYDIKVRA 990



 Score =  118 bits (295), Expect = 8e-26
 Identities = 192/823 (23%), Positives = 311/823 (37%), Gaps = 94/823 (11%)

Query: 862  ANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQ----ETTGTPRSDTVPSPR-DLQFV 916
            A  +T  D  P  +  + +  V  +   T V I      E T       +P P  DL   
Sbjct: 269  AEELTKEDEMPVGRNVLELSNVVRSANYTCVAISSLGMIEATAQVTVKALPKPPIDLVVT 328

Query: 917  EVTDVKVTIMWTPPESA-VTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYF 975
            E T   VT+ W    S  VT Y +        G   Q +     T   + GLSP   Y F
Sbjct: 329  ETTATSVTLTWDSGNSEPVTYYGIQYRAAGTEGPF-QEVDGVATTRYSIGGLSPFSEYAF 387

Query: 976  KVFAVS---HGRESKPLTAQ--QTTKLDAPTNLQFVNETDSTVLVRWTP---PRAQITGY 1027
            +V AV+    G  S+ + A+  +      P  +Q    + ST+LV+W P   P   + GY
Sbjct: 388  RVLAVNSIGRGPPSEAVRARTGEQAPSSPPRRVQARMLSASTMLVQWEPPEEPNGLVRGY 447

Query: 1028 RLTVGLTRRGQP---RQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTT 1084
            R+      R  P    ++N    +    + +L P   Y++ ++A     + P +  +   
Sbjct: 448  RVYYTPDSRRPPNAWHKHNTDAGLLT-TVGSLLPGITYSLRVLAFTAVGDGPPSPTIQVK 506

Query: 1085 LQPGSSIPP--YNTEV-TETTIVITWTPAPR---IGFKLGVRPSQGGEAPREVTSD-SGS 1137
             Q G    P  +  EV ++T I ++W   P+   I ++L    ++  +   +VT D + S
Sbjct: 507  TQQGVPAQPADFQAEVESDTRIQLSWLLPPQERIIMYELVYWAAEDEDQQHKVTFDPTSS 566

Query: 1138 IVVSGLTPGVEYVYTIQVLRD-GQERDAPIVNKVV---TPLSPPTNLHLEANPDTGVLTV 1193
              +  L P   Y + +    D G     P +       TP +PP  +   +   T V  V
Sbjct: 567  YTLEDLKPDTLYRFQLAARSDMGVGVFTPTIEARTAQSTPSAPPQKVMCVSMGSTTV-RV 625

Query: 1194 SW----ERSTTPDITGYRITTTPTNGQ-QGNSLEEVVHADQSSCTFDNLSPGLEYNVSVY 1248
            SW      S    IT Y +     +G+ +G  + + +  + SS     L    EY V V 
Sbjct: 626  SWVPPPADSRNGVITQYSVAYEAVDGEDRGRHVVDGISREHSSWDLVGLEKWTEYRVWVR 685

Query: 1249 TVKD---DKESVPI---SDTIIPAVPPPTDLRFTNIGPDTMRVTW-APPPS--------- 1292
               D     ES P+   +D  +P+  PP  +    +    + V W  P PS         
Sbjct: 686  AHTDVGPGPESSPVLVRTDEDVPS-GPPRKVEVEPLNSTAVHVYWKLPVPSKQHGQIRGY 744

Query: 1293 ----IDLTNFLVRYSPVKNEEDVAELSISP---SDNAVVLTNLLPGTEYVVSVSSVYEQH 1345
                + L N   R  P+  +  +AE    P    D    ++ L P T Y V+V++   + 
Sbjct: 745  QVTYVRLENGEPRGLPIIQDVMLAEAQWRPEESEDYETTISGLTPETTYSVTVAAYTTKG 804

Query: 1346 ESTPLRGRQKTGLDSPTG-------IDFSDITANSFTVHWIAPR---ATITGYRIRHHPE 1395
            +      R K  + + TG       +  S    N+  + W  P+     + GYR+++   
Sbjct: 805  DG----ARSKPKIVTTTGAVPGRPTMMISTTAMNTALLQWHPPKELPGELLGYRLQYCRA 860

Query: 1396 HFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN----GREESPLLIGQQSTVSDVP 1451
                RP            T+T L  GT Y+  + A N    G E    +   +   S  P
Sbjct: 861  D-EARPNTIDFGKDDQHFTVTGLHKGTTYIFRLAAKNRAGLGEEFEKEIRTPEDLPSGFP 919

Query: 1452 RDLEVVAATPTSLLISWDAPAVTVR-----YYRITYGETGGNSPVQEFTVPGSKSTATIS 1506
            ++L V   T ++  ++WD P +  R      Y + + +      +Q  T   + +  T++
Sbjct: 920  QNLHVTGLTTSTTELAWDPPVLAERNGRIISYTVVFRDINSQQELQNIT---TDTRFTLT 976

Query: 1507 GLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKW-LPS 1565
            GLKP   Y I V A T +G  P S    S     E       +V      S+ + W +P 
Sbjct: 977  GLKPDTTYDIKVRAWTSKGSGPLSPSIQSRTMPVEQVFAKNFRVAAAMKTSVLLSWEVPD 1036

Query: 1566 SSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEY 1608
            S     Y+     K        +  G    ++ I  LQP  EY
Sbjct: 1037 S-----YKSAVPFKILYNGQSVEVDGHSMRKL-IADLQPNTEY 1073



 Score =  108 bits (270), Expect = 6e-23
 Identities = 172/783 (21%), Positives = 290/783 (37%), Gaps = 91/783 (11%)

Query: 990  TAQQTTKL--DAPTNLQFVNETDSTVLVRWTPPRAQ-ITGYRLTVGLTRRGQPRQYNVGP 1046
            TAQ T K     P +L     T ++V + W    ++ +T Y +         P Q   G 
Sbjct: 310  TAQVTVKALPKPPIDLVVTETTATSVTLTWDSGNSEPVTYYGIQYRAAGTEGPFQEVDGV 369

Query: 1047 SVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFT-TLQPGSSIPPYNTE---VTETT 1102
            + ++Y +  L P SEY   ++A+      P +  V   T +   S PP   +   ++ +T
Sbjct: 370  ATTRYSIGGLSPFSEYAFRVLAVNSIGRGPPSEAVRARTGEQAPSSPPRRVQARMLSAST 429

Query: 1103 IVITWTPAPRI-----GFKLGVRPS--QGGEAPREVTSDSGSIVVSG-LTPGVEY---VY 1151
            +++ W P         G+++   P   +   A  +  +D+G +   G L PG+ Y   V 
Sbjct: 430  MLVQWEPPEEPNGLVRGYRVYYTPDSRRPPNAWHKHNTDAGLLTTVGSLLPGITYSLRVL 489

Query: 1152 TIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTT 1211
                + DG       V       + P +   E   DT +  +SW       I  Y +   
Sbjct: 490  AFTAVGDGPPSPTIQVKTQQGVPAQPADFQAEVESDTRI-QLSWLLPPQERIIMYELVYW 548

Query: 1212 PTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESV---PISDTIIPAVP 1268
                +  +   +V     SS T ++L P   Y   +    D    V    I      + P
Sbjct: 549  AAEDE--DQQHKVTFDPTSSYTLEDLKPDTLYRFQLAARSDMGVGVFTPTIEARTAQSTP 606

Query: 1269 --PPTDLRFTNIGPDTMRVTWAPPPSID----LTNFLVRYSPVKNEEDVAEL--SISPSD 1320
              PP  +   ++G  T+RV+W PPP+      +T + V Y  V  E+    +   IS   
Sbjct: 607  SAPPQKVMCVSMGSTTVRVSWVPPPADSRNGVITQYSVAYEAVDGEDRGRHVVDGISREH 666

Query: 1321 NAVVLTNLLPGTEYVVSV---SSVYEQHESTPLRGRQKTGLDS--PTGIDFSDITANSFT 1375
            ++  L  L   TEY V V   + V    ES+P+  R    + S  P  ++   + + +  
Sbjct: 667  SSWDLVGLEKWTEYRVWVRAHTDVGPGPESSPVLVRTDEDVPSGPPRKVEVEPLNSTAVH 726

Query: 1376 VHWIAP-----RATITGYRIRHHPEHFSGRPR-------------EDRVPHSRN-SITLT 1416
            V+W  P        I GY++  +    +G PR             + R   S +   T++
Sbjct: 727  VYWKLPVPSKQHGQIRGYQVT-YVRLENGEPRGLPIIQDVMLAEAQWRPEESEDYETTIS 785

Query: 1417 NLTPGTEYVVSIVAL----NGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPA 1472
             LTP T Y V++ A     +G    P ++     V   P  +    A  T+LL  W  P 
Sbjct: 786  GLTPETTYSVTVAAYTTKGDGARSKPKIVTTTGAVPGRPTMMISTTAMNTALL-QWHPPK 844

Query: 1473 V---TVRYYRITYGETGGNSPVQEFTVPGSKSTA--TISGLKPGVDYTITVYAVTGRGDS 1527
                 +  YR+ Y       P    T+   K     T++GL  G  Y   + A    G  
Sbjct: 845  ELPGELLGYRLQYCRADEARP---NTIDFGKDDQHFTVTGLHKGTTYIFRLAAKNRAGLG 901

Query: 1528 PASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLP-----SSSPVTGYRVTTTPKNGP 1582
                K I          P  + VT +  ++  + W P      +  +  Y V     N  
Sbjct: 902  EEFEKEIRTPEDLPSGFPQNLHVTGLTTSTTELAWDPPVLAERNGRIISYTVVFRDINSQ 961

Query: 1583 GPTKTKTAGPDQTEMTIEGLQPTVEYVVSV--YAQNPSGESQPLVQTAVTNIDR--PKGL 1638
               +  T     T  T+ GL+P   Y + V  +    SG   P +Q+    +++   K  
Sbjct: 962  QELQNITT---DTRFTLTGLKPDTTYDIKVRAWTSKGSGPLSPSIQSRTMPVEQVFAKNF 1018

Query: 1639 AFTDVDVDSIKIAWESPQGQVSR--YRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGS 1696
                    S+ ++WE P    S   +++ Y+     +       DG      +  L+P +
Sbjct: 1019 RVAAAMKTSVLLSWEVPDSYKSAVPFKILYNGQSVEV-------DGHSMRKLIADLQPNT 1071

Query: 1697 EYT 1699
            EY+
Sbjct: 1072 EYS 1074



 Score =  103 bits (256), Expect = 3e-21
 Identities = 197/902 (21%), Positives = 354/902 (39%), Gaps = 119/902 (13%)

Query: 1087 PGSSIPPYNTEV-----TETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVS 1141
            P  SIPP + EV        T V    P P + + +G       +   E+      + +S
Sbjct: 232  PRFSIPPSSQEVMPGGSVNLTCVAVGAPMPYVKWMMGAEELTKED---EMPVGRNVLELS 288

Query: 1142 GLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTP 1201
             +     Y           E  A +  K +    PP +L +     T V T++W+   + 
Sbjct: 289  NVVRSANYTCVAISSLGMIEATAQVTVKALP--KPPIDLVVTETTATSV-TLTWDSGNSE 345

Query: 1202 DITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKD-----DKES 1256
             +T Y I      G +G   +EV     +  +   LSP  EY   V  V         E+
Sbjct: 346  PVTYYGIQYRAA-GTEG-PFQEVDGVATTRYSIGGLSPFSEYAFRVLAVNSIGRGPPSEA 403

Query: 1257 VPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPP--PSIDLTNFLVRYSPVKNEEDVAEL 1314
            V           PP  ++   +   TM V W PP  P+  +  + V Y+P       A  
Sbjct: 404  VRARTGEQAPSSPPRRVQARMLSASTMLVQWEPPEEPNGLVRGYRVYYTPDSRRPPNAWH 463

Query: 1315 SISPSDNAVVLT--NLLPGTEY---VVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDI 1369
              + +D  ++ T  +LLPG  Y   V++ ++V +   S  ++ + + G+ +      +++
Sbjct: 464  KHN-TDAGLLTTVGSLLPGITYSLRVLAFTAVGDGPPSPTIQVKTQQGVPAQPADFQAEV 522

Query: 1370 TANS-FTVHWIAP-RATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVS 1427
             +++   + W+ P +  I  Y + +       +  +     + +S TL +L P T Y   
Sbjct: 523  ESDTRIQLSWLLPPQERIIMYELVYWAAEDEDQQHKVTFDPT-SSYTLEDLKPDTLYRFQ 581

Query: 1428 IVALNGREE---SPLLIGQ--QSTVSDVPRDLEVVAATPTSLLISWDAPAVTVR-----Y 1477
            + A +       +P +  +  QST S  P+ +  V+   T++ +SW  P    R      
Sbjct: 582  LAARSDMGVGVFTPTIEARTAQSTPSAPPQKVMCVSMGSTTVRVSWVPPPADSRNGVITQ 641

Query: 1478 YRITY----GETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKP 1533
            Y + Y    GE  G   V    +    S+  + GL+   +Y + V A T  G  P SS P
Sbjct: 642  YSVAYEAVDGEDRGRHVVDG--ISREHSSWDLVGLEKWTEYRVWVRAHTDVGPGPESS-P 698

Query: 1534 ISINYRTEIDKPS----QMQVTDVQDNSISVKW---LPSSS--PVTGYRVTTT------P 1578
            + +  RT+ D PS    +++V  +   ++ V W   +PS     + GY+VT        P
Sbjct: 699  VLV--RTDEDVPSGPPRKVEVEPLNSTAVHVYWKLPVPSKQHGQIRGYQVTYVRLENGEP 756

Query: 1579 KNGP-------GPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE---SQPLVQTA 1628
            +  P          + +    +  E TI GL P   Y V+V A    G+   S+P + T 
Sbjct: 757  RGLPIIQDVMLAEAQWRPEESEDYETTISGLTPETTYSVTVAAYTTKGDGARSKPKIVTT 816

Query: 1629 VTNIDRPKGLAFTDVDVDSIKIAWESPQ---GQVSRYRVTYSSPEDGIHELFPAPDGEED 1685
               +     +  +   +++  + W  P+   G++  YR+ Y   ++          G++D
Sbjct: 817  TGAVPGRPTMMISTTAMNTALLQWHPPKELPGELLGYRLQYCRADEARPNTIDF--GKDD 874

Query: 1686 TA-ELQGLRPGSEYTVSVVA-----LHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLS 1739
                + GL  G+ Y   + A     L ++ E + +   +      P +L  T +T ++  
Sbjct: 875  QHFTVTGLHKGTTYIFRLAAKNRAGLGEEFEKE-IRTPEDLPSGFPQNLHVTGLTTSTTE 933

Query: 1740 AQWTPP-----NVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYA 1794
              W PP     N ++  Y V           +E+      +   ++GL   T Y++ V A
Sbjct: 934  LAWDPPVLAERNGRIISYTVVF---RDINSQQELQNITTDTRFTLTGLKPDTTYDIKVRA 990

Query: 1795 LKDTLTSRPAQGVVTTLENVSPP------RRARVTDATETTITISWRTKTETITGFQVDA 1848
                 TS+ +  +  ++++ + P      +  RV  A +T++ +SW      +      A
Sbjct: 991  W----TSKGSGPLSPSIQSRTMPVEQVFAKNFRVAAAMKTSVLLSWE-----VPDSYKSA 1041

Query: 1849 VPA----NGQTPIQRTIKPDVRSYT--ITGLQPGTDYKIYLYTLNDNARSSPVVIDASTA 1902
            VP     NGQ+     ++ D  S    I  LQP T+Y   L     +A     ++   TA
Sbjct: 1042 VPFKILYNGQS-----VEVDGHSMRKLIADLQPNTEYSFVLMNRGSSAGGLQHLVSIRTA 1096

Query: 1903 ID 1904
             D
Sbjct: 1097 PD 1098



 Score = 82.8 bits (203), Expect = 4e-15
 Identities = 126/575 (21%), Positives = 224/575 (38%), Gaps = 76/575 (13%)

Query: 628  IQWNAPQPSHISKY-ILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQ 686
            + W  P    I  Y ++ W  ++   + K    P   +SYT++ LKP  +Y  QL +   
Sbjct: 530  LSWLLPPQERIIMYELVYWAAEDEDQQHKVTFDP--TSSYTLEDLKPDTLYRFQLAARSD 587

Query: 687  YGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWV----- 741
             G    T      T+ STP         + P   ++  S   T +      VSWV     
Sbjct: 588  MGVGVFTPTIEARTAQSTP---------SAPPQKVMCVSMGSTTVR-----VSWVPPPAD 633

Query: 742  SASDTVSGFRVEYELSEEGDEPQYL--DLPSTATSVNIPDLLPGRKYIVNVYQISEDG-- 797
            S +  ++ + V YE  +  D  +++   +    +S ++  L    +Y V V   ++ G  
Sbjct: 634  SRNGVITQYSVAYEAVDGEDRGRHVVDGISREHSSWDLVGLEKWTEYRVWVRAHTDVGPG 693

Query: 798  -EQSLILSTSQTTAPDAPPDPT-VDQVDDTSIVVRW-----SRPQAPITGYRIVYSPSVE 850
             E S +L  +    P  PP    V+ ++ T++ V W     S+    I GY++ Y     
Sbjct: 694  PESSPVLVRTDEDVPSGPPRKVEVEPLNSTAVHVYWKLPVPSKQHGQIRGYQVTYVRLEN 753

Query: 851  GSSTELNL------------PETAN--SVTLSDLQPGVQYNITIYAVE---ENQESTPVV 893
            G    L +            PE +     T+S L P   Y++T+ A     +   S P +
Sbjct: 754  GEPRGLPIIQDVMLAEAQWRPEESEDYETTISGLTPETTYSVTVAAYTTKGDGARSKPKI 813

Query: 894  IQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIM-WTPPE---SAVTGYRVDVIPVNLPGE 949
            +   TTG      VP  R    +  T +   ++ W PP+     + GYR+     +    
Sbjct: 814  V--TTTG-----AVPG-RPTMMISTTAMNTALLQWHPPKELPGELLGYRLQYCRADEARP 865

Query: 950  HGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPT----NLQF 1005
            +          F  VTGL  G TY F++ A +     +    +  T  D P+    NL  
Sbjct: 866  NTIDFGKDDQHFT-VTGLHKGTTYIFRLAAKNRAGLGEEFEKEIRTPEDLPSGFPQNLHV 924

Query: 1006 VNETDSTVLVRWTPP-RAQITGYRLTVGLTRR---GQPRQYNVGPSVSKYPLRNLQPASE 1061
               T ST  + W PP  A+  G  ++  +  R    Q    N+  + +++ L  L+P + 
Sbjct: 925  TGLTTSTTELAWDPPVLAERNGRIISYTVVFRDINSQQELQNI-TTDTRFTLTGLKPDTT 983

Query: 1062 YTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVT---ETTIVITWTPAPRIGFKLG 1118
            Y + + A       P +  + +   P   +   N  V    +T+++++W         + 
Sbjct: 984  YDIKVRAWTSKGSGPLSPSIQSRTMPVEQVFAKNFRVAAAMKTSVLLSWEVPDSYKSAVP 1043

Query: 1119 VRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTI 1153
             +    G++  EV   S   +++ L P  EY + +
Sbjct: 1044 FKILYNGQSV-EVDGHSMRKLIADLQPNTEYSFVL 1077


>gi|189217853 matrix metalloproteinase 2 isoform b [Homo sapiens]
          Length = 610

 Score =  146 bits (368), Expect = 3e-34
 Identities = 70/178 (39%), Positives = 97/178 (54%), Gaps = 16/178 (8%)

Query: 344 ETAVTQTYGGNSNGEPCVLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTD 403
           E  V +   GN++GE C  PF +NG+ + SCT  GR DG LWCSTT N+E+D KY FC  
Sbjct: 167 EGQVVRVKYGNADGEYCKFPFLFNGKEYNSCTDTGRSDGFLWCSTTYNFEKDGKYGFCPH 226

Query: 404 HTVLVQTRGGNSNGALCHFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPM 463
             +   T GGN+ G  C FPF +   +Y  CT+EGR D  +WCGTT++YD D+K+GFCP 
Sbjct: 227 EALF--TMGGNAEGQPCKFPFRFQGTSYDSCTTEGRTDGYRWCGTTEDYDRDKKYGFCPE 284

Query: 464 AAHEEICTTNEGV-----MYRIGDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRD 516
            A   +   +EG         +G++++          CT  G   G+  C   +   D
Sbjct: 285 TAMSTVGGNSEGAPCVFPFTFLGNKYES---------CTSAGRSDGKMWCATTANYDD 333



 Score =  145 bits (365), Expect = 6e-34
 Identities = 77/171 (45%), Positives = 97/171 (56%), Gaps = 18/171 (10%)

Query: 305 YGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPCVLPF 364
           Y  C TD+G   S G  W  T  N +      G    C   A+  T GGN+ G+PC  PF
Sbjct: 194 YNSC-TDTG--RSDGFLWCSTTYNFEKD----GKYGFCPHEALF-TMGGNAEGQPCKFPF 245

Query: 365 TYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALCHFPF 424
            + G ++ SCTTEGR DG+ WC TT +Y++D+KY FC +    + T GGNS GA C FPF
Sbjct: 246 RFQGTSYDSCTTEGRTDGYRWCGTTEDYDRDKKYGFCPE--TAMSTVGGNSEGAPCVFPF 303

Query: 425 LYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCP--------MAAHE 467
            +  + Y  CTS GR D   WC TT NYD D+K+GFCP        +AAHE
Sbjct: 304 TFLGNKYESCTSAGRSDGKMWCATTANYDDDRKWGFCPDQGYSLFLVAAHE 354


>gi|11342666 matrix metalloproteinase 2 isoform a preproprotein
           [Homo sapiens]
          Length = 660

 Score =  146 bits (368), Expect = 3e-34
 Identities = 70/178 (39%), Positives = 97/178 (54%), Gaps = 16/178 (8%)

Query: 344 ETAVTQTYGGNSNGEPCVLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTD 403
           E  V +   GN++GE C  PF +NG+ + SCT  GR DG LWCSTT N+E+D KY FC  
Sbjct: 217 EGQVVRVKYGNADGEYCKFPFLFNGKEYNSCTDTGRSDGFLWCSTTYNFEKDGKYGFCPH 276

Query: 404 HTVLVQTRGGNSNGALCHFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPM 463
             +   T GGN+ G  C FPF +   +Y  CT+EGR D  +WCGTT++YD D+K+GFCP 
Sbjct: 277 EALF--TMGGNAEGQPCKFPFRFQGTSYDSCTTEGRTDGYRWCGTTEDYDRDKKYGFCPE 334

Query: 464 AAHEEICTTNEGV-----MYRIGDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRD 516
            A   +   +EG         +G++++          CT  G   G+  C   +   D
Sbjct: 335 TAMSTVGGNSEGAPCVFPFTFLGNKYES---------CTSAGRSDGKMWCATTANYDD 383



 Score =  145 bits (365), Expect = 6e-34
 Identities = 77/171 (45%), Positives = 97/171 (56%), Gaps = 18/171 (10%)

Query: 305 YGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPCVLPF 364
           Y  C TD+G   S G  W  T  N +      G    C   A+  T GGN+ G+PC  PF
Sbjct: 244 YNSC-TDTG--RSDGFLWCSTTYNFEKD----GKYGFCPHEALF-TMGGNAEGQPCKFPF 295

Query: 365 TYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALCHFPF 424
            + G ++ SCTTEGR DG+ WC TT +Y++D+KY FC +    + T GGNS GA C FPF
Sbjct: 296 RFQGTSYDSCTTEGRTDGYRWCGTTEDYDRDKKYGFCPE--TAMSTVGGNSEGAPCVFPF 353

Query: 425 LYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCP--------MAAHE 467
            +  + Y  CTS GR D   WC TT NYD D+K+GFCP        +AAHE
Sbjct: 354 TFLGNKYESCTSAGRSDGKMWCATTANYDDDRKWGFCPDQGYSLFLVAAHE 404


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.132    0.408 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 106,538,076
Number of Sequences: 37866
Number of extensions: 5664247
Number of successful extensions: 23524
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 106
Number of HSP's successfully gapped in prelim test: 230
Number of HSP's that attempted gapping in prelim test: 11442
Number of HSP's gapped (non-prelim): 3626
length of query: 2330
length of database: 18,247,518
effective HSP length: 119
effective length of query: 2211
effective length of database: 13,741,464
effective search space: 30382376904
effective search space used: 30382376904
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 70 (31.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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