Guide to the Human Genome
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Search of human proteins with 47132551

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|47132551 fibronectin 1 isoform 2 preproprotein [Homo
sapiens]
         (2421 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|47132551 fibronectin 1 isoform 2 preproprotein [Homo sapiens]     5030   0.0  
gi|47132557 fibronectin 1 isoform 1 preproprotein [Homo sapiens]     5000   0.0  
gi|47132555 fibronectin 1 isoform 4 preproprotein [Homo sapiens]     3009   0.0  
gi|16933542 fibronectin 1 isoform 3 preproprotein [Homo sapiens]     3002   0.0  
gi|47132553 fibronectin 1 isoform 5 preproprotein [Homo sapiens]     2990   0.0  
gi|47132549 fibronectin 1 isoform 6 preproprotein [Homo sapiens]     2989   0.0  
gi|47132547 fibronectin 1 isoform 7 preproprotein [Homo sapiens]     1440   0.0  
gi|93141047 collagen, type XII, alpha 1 long isoform precursor [...   387   e-107
gi|153946395 tenascin C precursor [Homo sapiens]                      379   e-104
gi|157384973 tenascin R [Homo sapiens]                                329   2e-89
gi|62988324 tenascin N [Homo sapiens]                                 317   1e-85
gi|188528648 tenascin XB isoform 1 precursor [Homo sapiens]           308   3e-83
gi|93141049 collagen, type XII, alpha 1 short isoform precursor ...   291   7e-78
gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]         220   1e-56
gi|55743096 collagen, type XIV, alpha 1 [Homo sapiens]                211   7e-54
gi|157952215 protein tyrosine phosphatase, receptor type, B isof...   187   8e-47
gi|157952213 protein tyrosine phosphatase, receptor type, B isof...   187   8e-47
gi|110349719 titin isoform N2-A [Homo sapiens]                        175   4e-43
gi|110349717 titin isoform novex-2 [Homo sapiens]                     175   4e-43
gi|110349713 titin isoform novex-1 [Homo sapiens]                     175   4e-43
gi|110349715 titin isoform N2-B [Homo sapiens]                        175   4e-43
gi|119220552 sidekick 1 [Homo sapiens]                                166   3e-40
gi|222352127 sidekick 2 [Homo sapiens]                                165   4e-40
gi|109633039 protein tyrosine phosphatase, receptor type, F isof...   153   2e-36
gi|112734845 collagen, type XX, alpha 1 [Homo sapiens]                152   5e-36
gi|18860892 protein tyrosine phosphatase, receptor type, D isofo...   149   2e-35
gi|20665034 tenascin XB isoform 2 [Homo sapiens]                      148   7e-35
gi|109633041 protein tyrosine phosphatase, receptor type, F isof...   147   1e-34
gi|189217853 matrix metalloproteinase 2 isoform b [Homo sapiens]      146   3e-34
gi|11342666 matrix metalloproteinase 2 isoform a preproprotein [...   146   3e-34

>gi|47132551 fibronectin 1 isoform 2 preproprotein [Homo sapiens]
          Length = 2421

 Score = 5030 bits (13047), Expect = 0.0
 Identities = 2421/2421 (100%), Positives = 2421/2421 (100%)

Query: 1    MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ 60
            MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ
Sbjct: 1    MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ 60

Query: 61   INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI 120
            INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI
Sbjct: 61   INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI 120

Query: 121  WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK 180
            WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK
Sbjct: 121  WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK 180

Query: 181  PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY 240
            PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY
Sbjct: 181  PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY 240

Query: 241  RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP 300
            RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP
Sbjct: 241  RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP 300

Query: 301  QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC 360
            QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC
Sbjct: 301  QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC 360

Query: 361  VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC 420
            VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC
Sbjct: 361  VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC 420

Query: 421  HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI 480
            HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI
Sbjct: 421  HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI 480

Query: 481  GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM 540
            GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM
Sbjct: 481  GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM 540

Query: 541  LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ 600
            LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ
Sbjct: 541  LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ 600

Query: 601  PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP 660
            PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP
Sbjct: 601  PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP 660

Query: 661  GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP 720
            GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP
Sbjct: 661  GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP 720

Query: 721  LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL 780
            LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL
Sbjct: 721  LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL 780

Query: 781  LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITG 840
            LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITG
Sbjct: 781  LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITG 840

Query: 841  YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG 900
            YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG
Sbjct: 841  YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG 900

Query: 901  TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT 960
            TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT
Sbjct: 901  TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT 960

Query: 961  FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP 1020
            FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP
Sbjct: 961  FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP 1020

Query: 1021 RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG 1080
            RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG
Sbjct: 1021 RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG 1080

Query: 1081 VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV 1140
            VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV
Sbjct: 1081 VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV 1140

Query: 1141 SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT 1200
            SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT
Sbjct: 1141 SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT 1200

Query: 1201 PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS 1260
            PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS
Sbjct: 1201 PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS 1260

Query: 1261 DTIIPEVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIFEDFVDSSV 1320
            DTIIPEVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIFEDFVDSSV
Sbjct: 1261 DTIIPEVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIFEDFVDSSV 1320

Query: 1321 GYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAP 1380
            GYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAP
Sbjct: 1321 GYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAP 1380

Query: 1381 PPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTP 1440
            PPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTP
Sbjct: 1381 PPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTP 1440

Query: 1441 LRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHS 1500
            LRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHS
Sbjct: 1441 LRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHS 1500

Query: 1501 RNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWD 1560
            RNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWD
Sbjct: 1501 RNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWD 1560

Query: 1561 APAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPA 1620
            APAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPA
Sbjct: 1561 APAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPA 1620

Query: 1621 SSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKT 1680
            SSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKT
Sbjct: 1621 SSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKT 1680

Query: 1681 AGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIK 1740
            AGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIK
Sbjct: 1681 AGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIK 1740

Query: 1741 IAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDM 1800
            IAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDM
Sbjct: 1741 IAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDM 1800

Query: 1801 ESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEIN 1860
            ESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEIN
Sbjct: 1801 ESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEIN 1860

Query: 1861 LAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETT 1920
            LAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETT
Sbjct: 1861 LAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETT 1920

Query: 1921 ITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDN 1980
            ITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDN
Sbjct: 1921 ITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDN 1980

Query: 1981 ARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVP 2040
            ARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVP
Sbjct: 1981 ARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVP 2040

Query: 2041 RPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQKTPFVTHPGYDTGNGI 2100
            RPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQKTPFVTHPGYDTGNGI
Sbjct: 2041 RPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQKTPFVTHPGYDTGNGI 2100

Query: 2101 QLPGTSGQQPSVGQQMIFEEHGFRRTTPPTTATPIRHRPRPYPPNVGQEALSQTTISWAP 2160
            QLPGTSGQQPSVGQQMIFEEHGFRRTTPPTTATPIRHRPRPYPPNVGQEALSQTTISWAP
Sbjct: 2101 QLPGTSGQQPSVGQQMIFEEHGFRRTTPPTTATPIRHRPRPYPPNVGQEALSQTTISWAP 2160

Query: 2161 FQDTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHKVRE 2220
            FQDTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHKVRE
Sbjct: 2161 FQDTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHKVRE 2220

Query: 2221 EVVTVGNSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRC 2280
            EVVTVGNSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRC
Sbjct: 2221 EVVTVGNSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRC 2280

Query: 2281 DSSRWCHDNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEATCYDDGKTYHVG 2340
            DSSRWCHDNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEATCYDDGKTYHVG
Sbjct: 2281 DSSRWCHDNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEATCYDDGKTYHVG 2340

Query: 2341 EQWQKEYLGAICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYSQRYHQRTNTNV 2400
            EQWQKEYLGAICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYSQRYHQRTNTNV
Sbjct: 2341 EQWQKEYLGAICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYSQRYHQRTNTNV 2400

Query: 2401 NCPIECFMPLDVQADREDSRE 2421
            NCPIECFMPLDVQADREDSRE
Sbjct: 2401 NCPIECFMPLDVQADREDSRE 2421


>gi|47132557 fibronectin 1 isoform 1 preproprotein [Homo sapiens]
          Length = 2477

 Score = 5000 bits (12969), Expect = 0.0
 Identities = 2421/2477 (97%), Positives = 2421/2477 (97%), Gaps = 56/2477 (2%)

Query: 1    MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ 60
            MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ
Sbjct: 1    MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ 60

Query: 61   INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI 120
            INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI
Sbjct: 61   INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI 120

Query: 121  WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK 180
            WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK
Sbjct: 121  WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK 180

Query: 181  PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY 240
            PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY
Sbjct: 181  PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY 240

Query: 241  RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP 300
            RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP
Sbjct: 241  RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP 300

Query: 301  QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC 360
            QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC
Sbjct: 301  QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC 360

Query: 361  VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC 420
            VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC
Sbjct: 361  VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC 420

Query: 421  HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI 480
            HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI
Sbjct: 421  HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI 480

Query: 481  GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM 540
            GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM
Sbjct: 481  GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM 540

Query: 541  LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ 600
            LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ
Sbjct: 541  LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ 600

Query: 601  PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP 660
            PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP
Sbjct: 601  PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP 660

Query: 661  GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP 720
            GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP
Sbjct: 661  GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP 720

Query: 721  LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL 780
            LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL
Sbjct: 721  LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL 780

Query: 781  LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITG 840
            LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITG
Sbjct: 781  LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITG 840

Query: 841  YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG 900
            YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG
Sbjct: 841  YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG 900

Query: 901  TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT 960
            TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT
Sbjct: 901  TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT 960

Query: 961  FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP 1020
            FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP
Sbjct: 961  FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP 1020

Query: 1021 RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG 1080
            RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG
Sbjct: 1021 RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG 1080

Query: 1081 VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV 1140
            VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV
Sbjct: 1081 VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV 1140

Query: 1141 SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT 1200
            SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT
Sbjct: 1141 SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT 1200

Query: 1201 PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS 1260
            PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS
Sbjct: 1201 PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS 1260

Query: 1261 DTIIPEVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIFEDFVDSSV 1320
            DTIIPEVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIFEDFVDSSV
Sbjct: 1261 DTIIPEVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIFEDFVDSSV 1320

Query: 1321 GYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAP 1380
            GYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAP
Sbjct: 1321 GYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAP 1380

Query: 1381 PPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTP 1440
            PPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTP
Sbjct: 1381 PPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTP 1440

Query: 1441 LRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHS 1500
            LRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHS
Sbjct: 1441 LRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHS 1500

Query: 1501 RNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWD 1560
            RNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWD
Sbjct: 1501 RNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWD 1560

Query: 1561 APAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPA 1620
            APAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPA
Sbjct: 1561 APAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPA 1620

Query: 1621 SSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKT 1680
            SSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKT
Sbjct: 1621 SSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKT 1680

Query: 1681 AGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIK 1740
            AGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIK
Sbjct: 1681 AGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIK 1740

Query: 1741 IAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDM 1800
            IAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDM
Sbjct: 1741 IAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDM 1800

Query: 1801 ESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEIN 1860
            ESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEIN
Sbjct: 1801 ESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEIN 1860

Query: 1861 LAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETT 1920
            LAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETT
Sbjct: 1861 LAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETT 1920

Query: 1921 ITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDN 1980
            ITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDN
Sbjct: 1921 ITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDN 1980

Query: 1981 ARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVP 2040
            ARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVP
Sbjct: 1981 ARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVP 2040

Query: 2041 RPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKT------------------ 2082
            RPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKT                  
Sbjct: 2041 RPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELPQLVTLPHPNLHGPE 2100

Query: 2083 -------VQKTPFVTHPGYDTGNGIQLPGTSGQQPSVGQQMIFEEHGFRRTTPPTTATPI 2135
                   VQKTPFVTHPGYDTGNGIQLPGTSGQQPSVGQQMIFEEHGFRRTTPPTTATPI
Sbjct: 2101 ILDVPSTVQKTPFVTHPGYDTGNGIQLPGTSGQQPSVGQQMIFEEHGFRRTTPPTTATPI 2160

Query: 2136 RHRPRPYPPNVG-------------------------------QEALSQTTISWAPFQDT 2164
            RHRPRPYPPNVG                               QEALSQTTISWAPFQDT
Sbjct: 2161 RHRPRPYPPNVGEEIQIGHIPREDVDYHLYPHGPGLNPNASTGQEALSQTTISWAPFQDT 2220

Query: 2165 SEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHKVREEVVT 2224
            SEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHKVREEVVT
Sbjct: 2221 SEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHKVREEVVT 2280

Query: 2225 VGNSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSR 2284
            VGNSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSR
Sbjct: 2281 VGNSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSR 2340

Query: 2285 WCHDNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEATCYDDGKTYHVGEQWQ 2344
            WCHDNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEATCYDDGKTYHVGEQWQ
Sbjct: 2341 WCHDNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEATCYDDGKTYHVGEQWQ 2400

Query: 2345 KEYLGAICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYSQRYHQRTNTNVNCPI 2404
            KEYLGAICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYSQRYHQRTNTNVNCPI
Sbjct: 2401 KEYLGAICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYSQRYHQRTNTNVNCPI 2460

Query: 2405 ECFMPLDVQADREDSRE 2421
            ECFMPLDVQADREDSRE
Sbjct: 2461 ECFMPLDVQADREDSRE 2477


>gi|47132555 fibronectin 1 isoform 4 preproprotein [Homo sapiens]
          Length = 2330

 Score = 3009 bits (7800), Expect = 0.0
 Identities = 1515/2136 (70%), Positives = 1655/2136 (77%), Gaps = 76/2136 (3%)

Query: 1    MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ 60
            MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ
Sbjct: 1    MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ 60

Query: 61   INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI 120
            INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI
Sbjct: 61   INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI 120

Query: 121  WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK 180
            WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK
Sbjct: 121  WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK 180

Query: 181  PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY 240
            PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY
Sbjct: 181  PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY 240

Query: 241  RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP 300
            RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP
Sbjct: 241  RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP 300

Query: 301  QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC 360
            QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC
Sbjct: 301  QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC 360

Query: 361  VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC 420
            VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC
Sbjct: 361  VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC 420

Query: 421  HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI 480
            HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI
Sbjct: 421  HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI 480

Query: 481  GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM 540
            GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM
Sbjct: 481  GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM 540

Query: 541  LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ 600
            LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ
Sbjct: 541  LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ 600

Query: 601  PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP 660
            PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP
Sbjct: 601  PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP 660

Query: 661  GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP 720
            GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP
Sbjct: 661  GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP 720

Query: 721  LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL 780
            LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL
Sbjct: 721  LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL 780

Query: 781  LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITG 840
            LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITG
Sbjct: 781  LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITG 840

Query: 841  YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG 900
            YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG
Sbjct: 841  YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG 900

Query: 901  TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT 960
            TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT
Sbjct: 901  TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT 960

Query: 961  FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP 1020
            FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP
Sbjct: 961  FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP 1020

Query: 1021 RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG 1080
            RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG
Sbjct: 1021 RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG 1080

Query: 1081 VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV 1140
            VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV
Sbjct: 1081 VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV 1140

Query: 1141 SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT 1200
            SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT
Sbjct: 1141 SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT 1200

Query: 1201 PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS 1260
            PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS
Sbjct: 1201 PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS 1260

Query: 1261 DTIIPEVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIFEDFVDSSV 1320
            DTIIP VP  TDL F +I   ++ + W P  S  +  + +          + E  +  S 
Sbjct: 1261 DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSD 1320

Query: 1321 GYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAP 1380
                +T L PG +Y +SV ++    ES P    Q+T +  PT + F++I  ++  V W  
Sbjct: 1321 NAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIA 1380

Query: 1381 PPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTP 1440
            P +  +T + +R+ P        E  +  S N++ LTNL PGTEYVVS+ ++  + ES  
Sbjct: 1381 PRA-TITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPL 1439

Query: 1441 LRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHS 1500
            L G+Q T  D P  ++    T  S  + W AP  T+  YRI +     +   +E  VP S
Sbjct: 1440 LIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGS 1499

Query: 1501 RNSITLTNLTPGTEYVVSIVALNGREESPL----LIGQQSTVSDVPRDLEVVAATPTSLL 1556
            +++ T++ L PG +Y +++ A+ GR +SP     +     T  D P  ++V      S+ 
Sbjct: 1500 KSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSIS 1559

Query: 1557 ISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRG 1616
            + W   +  V  YR+T     G  P +  T    ++  TI GL+P V+Y ++VYA    G
Sbjct: 1560 VKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSG 1619

Query: 1617 DSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVT-TTPKNGPGP 1675
            +    S+P+     T ID+P  +  TDV  +SI + W      V+ YRVT ++P++G   
Sbjct: 1620 E----SQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHE 1675

Query: 1676 TKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVD 1735
                  G + T   ++GL+P  EY VSV A +   ESQPL+ T  T I  P  L FT V 
Sbjct: 1676 LFPAPDGEEDT-AELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVT 1734

Query: 1736 VDSIKIAWESPQGQVSRYRVTYSSPE--DGIHELFPAPDGEEDTAELQGLRPGSEYTVSV 1793
              S+   W  P  Q++ YRV  +  E    + E+  APD    +  + GL   ++Y VSV
Sbjct: 1735 PTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPD--SSSVVVSGLMVATKYEVSV 1792

Query: 1794 VALHDDMESQPLIGTQSTA--IPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKE 1851
             AL D + S+P  G  +T   +  P   + T  T T+++  W      +TG++V   P  
Sbjct: 1793 YALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPAN 1852

Query: 1852 KTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRA 1911
               P++   + PD  S  ++GL   T Y++ +Y L D   S P   V+     +  P   
Sbjct: 1853 GQTPIQR-TIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPV--VIDASTAIDAPSNL 1909

Query: 1912 RVTDATETTITISWRTKTETITGFQVD-AVPANGQTPIQRTIKPDVRSYTITGLQPGTDY 1970
            R    T  ++ +SW+     ITG+ +    P +    +    +P V   TITGL+PGT+Y
Sbjct: 1910 RFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEY 1969

Query: 1971 KIYLYTLNDNARSSPVV----------------IDASTAIDAPSNL-------------- 2000
             IY+  L +N +S P++                 D    I  P                 
Sbjct: 1970 TIYVIALKNNQKSEPLIGRKKTVQKTPFVTHPGYDTGNGIQLPGTSGQQPSVGQQMIFEE 2029

Query: 2001 -RFLATTP-----------------------NSLLVSWQPPRARITGYIIKYEKPGSPPR 2036
              F  TTP                       +   +SW P +   + YII     G+   
Sbjct: 2030 HGFRRTTPPTTATPIRHRPRPYPPNVGQEALSQTTISWAPFQ-DTSEYIISCHPVGTDEE 2088

Query: 2037 EVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQK 2072
             +  R     T AT+TGL  G  Y I V ALK+ Q+
Sbjct: 2089 PLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQR 2124



 Score = 2386 bits (6184), Expect = 0.0
 Identities = 1233/1693 (72%), Positives = 1345/1693 (79%), Gaps = 60/1693 (3%)

Query: 768  LPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAP------------- 814
            +P    S  I  L PG  Y   +  I + G Q +      TT+   P             
Sbjct: 659  IPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPF 718

Query: 815  -----PDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTE-LNLPETANSVTLS 868
                    +V ++  +S VV W      ++G+R+ Y  S EG   + L+LP TA SV + 
Sbjct: 719  SPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIP 778

Query: 869  DLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWT 928
            DL PG +Y + +Y + E+ E + ++   +TT         +P D    +V D  + + W+
Sbjct: 779  DLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPD------APPDPTVDQVDDTSIVVRWS 832

Query: 929  PPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKP 988
             P++ +TGYR+   P          LP + N+   ++ L PGV Y   ++AV   +ES P
Sbjct: 833  RPQAPITGYRIVYSPSVEGSSTELNLPETANSVT-LSDLQPGVQYNITIYAVEENQESTP 891

Query: 989  LTAQQTTK-------LDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQ 1041
            +  QQ T        + +P +LQFV  TD  V + WTPP + +TGYR+ V       P +
Sbjct: 892  VVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDV--IPVNLPGE 949

Query: 1042 YNVGPSVSKYP---LRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEV 1098
            +     +S+     +  L P   Y   + A+   +ES   T   TT     +   +  E 
Sbjct: 950  HGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNE- 1008

Query: 1099 TETTIVITWTP--APRIGFKLGVRPSQGGEAPRE--VTSDSGSIVVSGLTPGVEYVYTIQ 1154
            T++T+++ WTP  A   G++L V  ++ G+ PR+  V        +  L P  EY  ++ 
Sbjct: 1009 TDSTVLVRWTPPRAQITGYRLTVGLTRRGQ-PRQYNVGPSVSKYPLRNLQPASEYTVSLV 1067

Query: 1155 VLRDGQERDAPIVNKVVTPLSPPTNL---HLEANPDTGVLTVSWERSTTPDITGYRITTT 1211
             ++  QE  +P    V T L P +++   + E    T V+T  W   T     G+++   
Sbjct: 1068 AIKGNQE--SPKATGVFTTLQPGSSIPPYNTEVTETTIVIT--W---TPAPRIGFKLGVR 1120

Query: 1212 PTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKE-SVPISDTIIPEVPQL 1270
            P+   QG      V +D  S     L+PG+EY  ++  ++D +E   PI + ++  +   
Sbjct: 1121 PS---QGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPP 1177

Query: 1271 TDLSFVDITDSSI-GLRWTPLNSSTIIGYRITVVAA-GEGIPIFEDFVDSSVGYYTVTGL 1328
            T+L      D+ +  + W    +  I GYRIT     G+     E+ V +     T   L
Sbjct: 1178 TNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNL 1237

Query: 1329 EPGIDYDISVITLINGGESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTN 1388
             PG++Y++SV T+ +  ES P + T   AVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTN
Sbjct: 1238 SPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTN 1297

Query: 1389 FLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTG 1448
            FLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTG
Sbjct: 1298 FLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTG 1357

Query: 1449 LDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTN 1508
            LDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTN
Sbjct: 1358 LDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTN 1417

Query: 1509 LTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRY 1568
            LTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRY
Sbjct: 1418 LTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRY 1477

Query: 1569 YRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISIN 1628
            YRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISIN
Sbjct: 1478 YRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISIN 1537

Query: 1629 YRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEM 1688
            YRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEM
Sbjct: 1538 YRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEM 1597

Query: 1689 TIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQG 1748
            TIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQG
Sbjct: 1598 TIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQG 1657

Query: 1749 QVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGT 1808
            QVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGT
Sbjct: 1658 QVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGT 1717

Query: 1809 QSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSV 1868
            QSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSV
Sbjct: 1718 QSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSV 1777

Query: 1869 VVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTK 1928
            VVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTK
Sbjct: 1778 VVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTK 1837

Query: 1929 TETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVI 1988
            TETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVI
Sbjct: 1838 TETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVI 1897

Query: 1989 DASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTE 2048
            DASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTE
Sbjct: 1898 DASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTE 1957

Query: 2049 ATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQKTPFVTHPGYDTGNGIQLPGTSGQ 2108
            ATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQKTPFVTHPGYDTGNGIQLPGTSGQ
Sbjct: 1958 ATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQKTPFVTHPGYDTGNGIQLPGTSGQ 2017

Query: 2109 QPSVGQQMIFEEHGFRRTTPPTTATPIRHRPRPYPPNVGQEALSQTTISWAPFQDTSEYI 2168
            QPSVGQQMIFEEHGFRRTTPPTTATPIRHRPRPYPPNVGQEALSQTTISWAPFQDTSEYI
Sbjct: 2018 QPSVGQQMIFEEHGFRRTTPPTTATPIRHRPRPYPPNVGQEALSQTTISWAPFQDTSEYI 2077

Query: 2169 ISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHKVREEVVTVGNS 2228
            ISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHKVREEVVTVGNS
Sbjct: 2078 ISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHKVREEVVTVGNS 2137

Query: 2229 VNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHD 2288
            VNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHD
Sbjct: 2138 VNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHD 2197

Query: 2289 NGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEATCYDDGKTYHVGEQWQKEYL 2348
            NGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEATCYDDGKTYHVGEQWQKEYL
Sbjct: 2198 NGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEATCYDDGKTYHVGEQWQKEYL 2257

Query: 2349 GAICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYSQRYHQRTNTNVNCPIECFM 2408
            GAICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYSQRYHQRTNTNVNCPIECFM
Sbjct: 2258 GAICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYSQRYHQRTNTNVNCPIECFM 2317

Query: 2409 PLDVQADREDSRE 2421
            PLDVQADREDSRE
Sbjct: 2318 PLDVQADREDSRE 2330



 Score =  115 bits (287), Expect = 7e-25
 Identities = 57/129 (44%), Positives = 74/129 (57%), Gaps = 5/129 (3%)

Query: 2238 DDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHDNGVNYKIGE 2297
            +++CFD YT + Y VGD +ER  +S     C C+G G G   C  +  CH+ G +YKIG+
Sbjct: 94   EETCFDKYTGNTYRVGDTYERPKDSMI-WDCTCIGAGRGRISCTIANRCHEGGQSYKIGD 152

Query: 2298 KWDRQGE-NGQMMSCTCLGNGKGEFKCDPHEATCYDD--GKTYHVGEQWQKEYLG-AICS 2353
             W R  E  G M+ C CLGNGKGE+ C P    C+D   G +Y VGE W+K Y G  +  
Sbjct: 153  TWRRPHETGGYMLECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQGWMMVD 212

Query: 2354 CTCFGGQRG 2362
            CTC G   G
Sbjct: 213  CTCLGEGSG 221



 Score =  115 bits (287), Expect = 7e-25
 Identities = 57/129 (44%), Positives = 74/129 (57%), Gaps = 5/129 (3%)

Query: 94   EETCFDKYTGNTYRVGDTYERPKDSMI-WDCTCIGAGRGRISCTIANRCHEGGQSYKIGD 152
            +++CFD YT + Y VGD +ER  +S     C C+G G G   C  +  CH+ G +YKIG+
Sbjct: 2147 DDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHDNGVNYKIGE 2206

Query: 153  TWRRPHETGGYMLECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQGWMMVD 212
             W R  E  G M+ C CLGNGKGE+ C P    C+D   G +Y VGE W+K Y G  +  
Sbjct: 2207 KWDRQGE-NGQMMSCTCLGNGKGEFKCDPHEATCYDD--GKTYHVGEQWQKEYLG-AICS 2262

Query: 213  CTCLGEGSG 221
            CTC G   G
Sbjct: 2263 CTCFGGQRG 2271



 Score = 98.6 bits (244), Expect = 7e-20
 Identities = 54/172 (31%), Positives = 73/172 (42%), Gaps = 34/172 (19%)

Query: 2221 EVVTVGNSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRC 2280
            E V +GN   E   +P  + CFD    + Y VG+ WE+  +    + C CLG GSG   C
Sbjct: 166  ECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITC 225

Query: 2281 DSSRWCHDNG--VNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPH------------ 2326
             S   C+D     +Y+IG+ W ++   G ++ C C GNG+GE+KC+ H            
Sbjct: 226  TSRNRCNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGP 285

Query: 2327 ----EATCY----------------DDGKTYHVGEQWQKEYLGAICSCTCFG 2358
                 A  Y                D G  Y VG QW K        CTC G
Sbjct: 286  FTDVRAAVYQPQPHPQPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLG 337



 Score = 98.6 bits (244), Expect = 7e-20
 Identities = 54/172 (31%), Positives = 73/172 (42%), Gaps = 34/172 (19%)

Query: 166  ECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITC 225
            E V +GN   E   +P  + CFD    + Y VG+ WE+  +    + C CLG GSG   C
Sbjct: 2130 EVVTVGNSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRC 2189

Query: 226  TSRNRCNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGP 285
             S   C+D     +Y+IG+ W ++   G ++ C C GNG+GE+KC+ H            
Sbjct: 2190 DSSRWCHDNG--VNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPH------------ 2235

Query: 286  FTDVRAAVYQPQPHPQPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLG 337
                 A  Y                D G  Y VG QW K        CTC G
Sbjct: 2236 ----EATCY----------------DDGKTYHVGEQWQKEYLGAICSCTCFG 2267



 Score = 90.9 bits (224), Expect = 1e-17
 Identities = 40/123 (32%), Positives = 65/123 (52%), Gaps = 8/123 (6%)

Query: 2250 YAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHD----NGVNYKIGEKWDRQGEN 2305
            Y +GD+W++  + G  + C C+G G G + C +     D    + + Y + + + ++ E 
Sbjct: 478  YRIGDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEE 537

Query: 2306 GQMMSCTCLGNGKGEFKCDPHEATCYDD--GKTYHVGEQWQKEYLGAICSCTCFG-GQRG 2362
            G M++CTC G G+G +KCDP +  C D   G  Y +G+ W+K   G    C C+G G   
Sbjct: 538  GHMLNCTCFGQGRGRWKCDPVD-QCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGE 596

Query: 2363 WRC 2365
            W C
Sbjct: 597  WHC 599



 Score = 90.9 bits (224), Expect = 1e-17
 Identities = 40/123 (32%), Positives = 65/123 (52%), Gaps = 8/123 (6%)

Query: 478  YRIGDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEE 537
            Y +GD+W++  + G  + C C+G G G + C +     D    + + Y + + + ++ E 
Sbjct: 2159 YAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHD----NGVNYKIGEKWDRQGEN 2214

Query: 538  GHMLNCTCFGQGRGRWKCDPVD-QCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGE 596
            G M++CTC G G+G +KCDP +  C D   G  Y +G+ W+K   G    C C+G G   
Sbjct: 2215 GQMMSCTCLGNGKGEFKCDPHEATCYDD--GKTYHVGEQWQKEYLGAICSCTCFG-GQRG 2271

Query: 597  WHC 599
            W C
Sbjct: 2272 WRC 2274



 Score = 88.2 bits (217), Expect = 9e-17
 Identities = 45/124 (36%), Positives = 65/124 (52%), Gaps = 7/124 (5%)

Query: 2250 YAVGDEWERMSESG-FKLLCQCLGFGSGHFRCDS-SRWCHDN--GVNYKIGEKWDRQGEN 2305
            Y +GD W R  E+G + L C CLG G G + C   +  C D+  G +Y +GE W++  + 
Sbjct: 148  YKIGDTWRRPHETGGYMLECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQG 207

Query: 2306 GQMMSCTCLGNGKGEFKCDPHEATCYDDGKT-YHVGEQW-QKEYLGAICSCTCFGGQRG- 2362
              M+ CTCLG G G   C         D +T Y +G+ W +K+  G +  C C G  RG 
Sbjct: 208  WMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGE 267

Query: 2363 WRCD 2366
            W+C+
Sbjct: 268  WKCE 271



 Score = 88.2 bits (217), Expect = 9e-17
 Identities = 45/124 (36%), Positives = 65/124 (52%), Gaps = 7/124 (5%)

Query: 148  YKIGDTWRRPHETGGYMLECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQG 207
            Y +GD W R  E+G + L C CLG G G + C   +  C D+  G +Y +GE W++  + 
Sbjct: 2159 YAVGDEWERMSESG-FKLLCQCLGFGSGHFRCDS-SRWCHDN--GVNYKIGEKWDRQGEN 2214

Query: 208  WMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGE 267
              M+ CTCLG G G   C         D +T Y +G+ W +K+  G +  C C G  RG 
Sbjct: 2215 GQMMSCTCLGNGKGEFKCDPHEATCYDDGKT-YHVGEQW-QKEYLGAICSCTCFGGQRG- 2271

Query: 268  WKCE 271
            W+C+
Sbjct: 2272 WRCD 2275



 Score = 79.7 bits (195), Expect = 3e-14
 Identities = 37/84 (44%), Positives = 54/84 (64%), Gaps = 5/84 (5%)

Query: 2288 DNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEA---TCYDDGKTYHVGEQWQ 2344
            + GV Y+IG++WD+Q + G MM CTC+GNG+GE+ C  +      C  D  TY+V + + 
Sbjct: 473  NEGVMYRIGDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFH 532

Query: 2345 KEY-LGAICSCTCFGGQRG-WRCD 2366
            K +  G + +CTCFG  RG W+CD
Sbjct: 533  KRHEEGHMLNCTCFGQGRGRWKCD 556



 Score = 79.7 bits (195), Expect = 3e-14
 Identities = 37/84 (44%), Positives = 54/84 (64%), Gaps = 5/84 (5%)

Query: 473  NEGVMYRIGDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFH 532
            + GV Y+IG++WD+Q + G MM CTC+GNG+GE+ C  +      C  D  TY+V + + 
Sbjct: 2197 DNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEA---TCYDDGKTYHVGEQWQ 2253

Query: 533  KRHEEGHMLNCTCFGQGRGRWKCD 556
            K +  G + +CTCFG  RG W+CD
Sbjct: 2254 KEY-LGAICSCTCFGGQRG-WRCD 2275



 Score = 63.5 bits (153), Expect = 2e-09
 Identities = 32/82 (39%), Positives = 46/82 (56%), Gaps = 7/82 (8%)

Query: 2286 CHDNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPH---EATCYD--DGKTYHVG 2340
            C+DNG +Y+I ++W+R    G  + CTC G  +G F C+     E TC+D   G TY VG
Sbjct: 52   CYDNGKHYQINQQWERT-YLGNALVCTCYGGSRG-FNCESKPEAEETCFDKYTGNTYRVG 109

Query: 2341 EQWQKEYLGAICSCTCFGGQRG 2362
            + +++     I  CTC G  RG
Sbjct: 110  DTYERPKDSMIWDCTCIGAGRG 131



 Score = 63.5 bits (153), Expect = 2e-09
 Identities = 32/82 (39%), Positives = 46/82 (56%), Gaps = 7/82 (8%)

Query: 52   CYDNGKHYQINQQWERT-YLGNALVCTCYGGSRG-FNCESKPEAEETCFDKYTGNTYRVG 109
            C+DNG +Y+I ++W+R    G  + CTC G  +G F C+     E TC+D   G TY VG
Sbjct: 2195 CHDNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPH---EATCYD--DGKTYHVG 2249

Query: 110  DTYERPKDSMIWDCTCIGAGRG 131
            + +++     I  CTC G  RG
Sbjct: 2250 EQWQKEYLGAICSCTCFGGQRG 2271



 Score = 62.0 bits (149), Expect = 7e-09
 Identities = 37/107 (34%), Positives = 49/107 (45%), Gaps = 10/107 (9%)

Query: 2225 VGNSVNE----GLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRC 2280
            VGN   E      +Q  D    D  T   Y V D + +  E G  L C C G G G ++C
Sbjct: 499  VGNGRGEWTCIAYSQLRDQCIVDDIT---YNVNDTFHKRHEEGHMLNCTCFGQGRGRWKC 555

Query: 2281 DSSRWCHDN--GVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDP 2325
            D    C D+  G  Y+IG+ W++   +G    C C G G GE+ C P
Sbjct: 556  DPVDQCQDSETGTFYQIGDSWEKY-VHGVRYQCYCYGRGIGEWHCQP 601



 Score = 62.0 bits (149), Expect = 7e-09
 Identities = 37/107 (34%), Positives = 49/107 (45%), Gaps = 10/107 (9%)

Query: 499  VGNGRGEWTCIAYSQLRDQCIVDDIT---YNVNDTFHKRHEEGHMLNCTCFGQGRGRWKC 555
            VGN   E      +Q  D    D  T   Y V D + +  E G  L C C G G G ++C
Sbjct: 2134 VGNSVNE----GLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRC 2189

Query: 556  DPVDQCQDSETGTFYQIGDSWEKY-VHGVRYQCYCYGRGIGEWHCQP 601
            D    C D+  G  Y+IG+ W++   +G    C C G G GE+ C P
Sbjct: 2190 DSSRWCHDN--GVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDP 2234



 Score = 57.8 bits (138), Expect = 1e-07
 Identities = 24/62 (38%), Positives = 35/62 (56%), Gaps = 6/62 (9%)

Query: 2330 CYDDGKTYHVGEQWQKEYLGAICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYS 2389
            CYD+GK Y + +QW++ YLG    CTC+GG RG+ C++      +P  E T    Y   +
Sbjct: 52   CYDNGKHYQINQQWERTYLGNALVCTCYGGSRGFNCES------KPEAEETCFDKYTGNT 105

Query: 2390 QR 2391
             R
Sbjct: 106  YR 107



 Score = 57.8 bits (138), Expect = 1e-07
 Identities = 24/62 (38%), Positives = 35/62 (56%), Gaps = 6/62 (9%)

Query: 52   CYDNGKHYQINQQWERTYLGNALVCTCYGGSRGFNCES------KPEAEETCFDKYTGNT 105
            CYD+GK Y + +QW++ YLG    CTC+GG RG+ C++      +P  E T    Y   +
Sbjct: 2239 CYDDGKTYHVGEQWQKEYLGAICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYS 2298

Query: 106  YR 107
             R
Sbjct: 2299 QR 2300



 Score = 50.1 bits (118), Expect = 3e-05
 Identities = 31/110 (28%), Positives = 42/110 (38%), Gaps = 34/110 (30%)

Query: 2241 CFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDS------------------ 2282
            C D  T + Y +GD W +    G  L C C G G G ++C+                   
Sbjct: 231  CNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVR 290

Query: 2283 ---------------SRWCHDNGVNYKIGEKWDRQGENGQMMSCTCLGNG 2317
                                D+GV Y +G +W +   N QM+ CTCLGNG
Sbjct: 291  AAVYQPQPHPQPPPYGHCVTDSGVVYSVGMQWLKTQGNKQML-CTCLGNG 339



 Score = 50.1 bits (118), Expect = 3e-05
 Identities = 31/110 (28%), Positives = 42/110 (38%), Gaps = 34/110 (30%)

Query: 231  CNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVR 290
            C D  T + Y +GD W +    G  L C C G G G ++C+                   
Sbjct: 2150 CFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDS------------------ 2191

Query: 291  AAVYQPQPHPQPPPYGHCVTDSGVVYSVGMQWLKTQGNKQML-CTCLGNG 339
                                D+GV Y +G +W +   N QM+ CTCLGNG
Sbjct: 2192 ---------------SRWCHDNGVNYKIGEKWDRQGENGQMMSCTCLGNG 2226


>gi|16933542 fibronectin 1 isoform 3 preproprotein [Homo sapiens]
          Length = 2355

 Score = 3002 bits (7783), Expect = 0.0
 Identities = 1486/1997 (74%), Positives = 1617/1997 (80%), Gaps = 21/1997 (1%)

Query: 1    MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ 60
            MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ
Sbjct: 1    MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ 60

Query: 61   INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI 120
            INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI
Sbjct: 61   INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI 120

Query: 121  WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK 180
            WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK
Sbjct: 121  WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK 180

Query: 181  PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY 240
            PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY
Sbjct: 181  PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY 240

Query: 241  RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP 300
            RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP
Sbjct: 241  RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP 300

Query: 301  QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC 360
            QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC
Sbjct: 301  QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC 360

Query: 361  VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC 420
            VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC
Sbjct: 361  VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC 420

Query: 421  HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI 480
            HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI
Sbjct: 421  HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI 480

Query: 481  GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM 540
            GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM
Sbjct: 481  GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM 540

Query: 541  LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ 600
            LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ
Sbjct: 541  LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ 600

Query: 601  PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP 660
            PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP
Sbjct: 601  PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP 660

Query: 661  GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP 720
            GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP
Sbjct: 661  GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP 720

Query: 721  LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL 780
            LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL
Sbjct: 721  LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL 780

Query: 781  LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITG 840
            LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITG
Sbjct: 781  LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITG 840

Query: 841  YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG 900
            YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG
Sbjct: 841  YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG 900

Query: 901  TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT 960
            TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT
Sbjct: 901  TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT 960

Query: 961  FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP 1020
            FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP
Sbjct: 961  FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP 1020

Query: 1021 RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG 1080
            RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG
Sbjct: 1021 RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG 1080

Query: 1081 VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV 1140
            VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV
Sbjct: 1081 VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV 1140

Query: 1141 SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT 1200
            SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT
Sbjct: 1141 SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT 1200

Query: 1201 PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS 1260
            PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS
Sbjct: 1201 PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS 1260

Query: 1261 DTIIPEVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIFEDFVDSSV 1320
            DTIIP VP  TDL F +I   ++ + W P  S  +  + +          + E  +  S 
Sbjct: 1261 DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSD 1320

Query: 1321 GYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAP 1380
                +T L PG +Y +SV ++    ES P    Q+T +  PT + F++I  ++  V W  
Sbjct: 1321 NAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIA 1380

Query: 1381 PPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTP 1440
            P +  +T + +R+ P        E  +  S N++ LTNL PGTEYVVS+ ++  + ES  
Sbjct: 1381 PRA-TITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPL 1439

Query: 1441 LRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHS 1500
            L G+Q T  D P  ++    T  S  + W AP  T+  YRI +     +   +E  VP S
Sbjct: 1440 LIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGS 1499

Query: 1501 RNSITLTNLTPGTEYVVSIVALNGREESPL----LIGQQSTVSDVPRDLEVVAATPTSLL 1556
            +++ T++ L PG +Y +++ A+ GR +SP     +     T  D P  ++V      S+ 
Sbjct: 1500 KSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSIS 1559

Query: 1557 ISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRG 1616
            + W   +  V  YR+T     G  P +  T    ++  TI GL+P V+Y ++VYA    G
Sbjct: 1560 VKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSG 1619

Query: 1617 DSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVT-TTPKNGPGP 1675
            +    S+P+     T ID+P  +  TDV  +SI + W      V+ YRVT ++P++G   
Sbjct: 1620 E----SQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHE 1675

Query: 1676 TKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVD 1735
                  G + T   ++GL+P  EY VSV A +   ESQPL+ T  T I  P  L FT V 
Sbjct: 1676 LFPAPDGEEDT-AELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVT 1734

Query: 1736 VDSIKIAWESPQGQVSRYRVTYSSPE--DGIHELFPAPDGEEDTAELQGLRPGSEYTVSV 1793
              S+   W  P  Q++ YRV  +  E    + E+  APD    +  + GL   ++Y VSV
Sbjct: 1735 PTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPD--SSSVVVSGLMVATKYEVSV 1792

Query: 1794 VALHDDMESQPLIGTQSTA--IPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKE 1851
             AL D + S+P  G  +T   +  P   + T  T T+++  W      +TG++V   P  
Sbjct: 1793 YALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPAN 1852

Query: 1852 KTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRA 1911
               P++   + PD  S  ++GL   T Y++ +Y L D   S P   V+     +  P   
Sbjct: 1853 GQTPIQR-TIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPV--VIDASTAIDAPSNL 1909

Query: 1912 RVTDATETTITISWRTKTETITGFQVD-AVPANGQTPIQRTIKPDVRSYTITGLQPGTDY 1970
            R    T  ++ +SW+     ITG+ +    P +    +    +P V   TITGL+PGT+Y
Sbjct: 1910 RFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEY 1969

Query: 1971 KIYLYTLNDNARSSPVV 1987
             IY+  L +N +S P++
Sbjct: 1970 TIYVIALKNNQKSEPLI 1986



 Score = 2372 bits (6148), Expect = 0.0
 Identities = 1233/1718 (71%), Positives = 1345/1718 (78%), Gaps = 85/1718 (4%)

Query: 768  LPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAP------------- 814
            +P    S  I  L PG  Y   +  I + G Q +      TT+   P             
Sbjct: 659  IPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPF 718

Query: 815  -----PDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTE-LNLPETANSVTLS 868
                    +V ++  +S VV W      ++G+R+ Y  S EG   + L+LP TA SV + 
Sbjct: 719  SPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIP 778

Query: 869  DLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWT 928
            DL PG +Y + +Y + E+ E + ++   +TT         +P D    +V D  + + W+
Sbjct: 779  DLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPD------APPDPTVDQVDDTSIVVRWS 832

Query: 929  PPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKP 988
             P++ +TGYR+   P          LP + N+   ++ L PGV Y   ++AV   +ES P
Sbjct: 833  RPQAPITGYRIVYSPSVEGSSTELNLPETANSVT-LSDLQPGVQYNITIYAVEENQESTP 891

Query: 989  LTAQQTTK-------LDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQ 1041
            +  QQ T        + +P +LQFV  TD  V + WTPP + +TGYR+ V       P +
Sbjct: 892  VVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDV--IPVNLPGE 949

Query: 1042 YNVGPSVSKYP---LRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEV 1098
            +     +S+     +  L P   Y   + A+   +ES   T   TT     +   +  E 
Sbjct: 950  HGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNE- 1008

Query: 1099 TETTIVITWTP--APRIGFKLGVRPSQGGEAPRE--VTSDSGSIVVSGLTPGVEYVYTIQ 1154
            T++T+++ WTP  A   G++L V  ++ G+ PR+  V        +  L P  EY  ++ 
Sbjct: 1009 TDSTVLVRWTPPRAQITGYRLTVGLTRRGQ-PRQYNVGPSVSKYPLRNLQPASEYTVSLV 1067

Query: 1155 VLRDGQERDAPIVNKVVTPLSPPTNL---HLEANPDTGVLTVSWERSTTPDITGYRITTT 1211
             ++  QE  +P    V T L P +++   + E    T V+T  W   T     G+++   
Sbjct: 1068 AIKGNQE--SPKATGVFTTLQPGSSIPPYNTEVTETTIVIT--W---TPAPRIGFKLGVR 1120

Query: 1212 PTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKE-SVPISDTIIPEVPQL 1270
            P+   QG      V +D  S     L+PG+EY  ++  ++D +E   PI + ++  +   
Sbjct: 1121 PS---QGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPP 1177

Query: 1271 TDLSFVDITDSSI-GLRWTPLNSSTIIGYRITVVAA-GEGIPIFEDFVDSSVGYYTVTGL 1328
            T+L      D+ +  + W    +  I GYRIT     G+     E+ V +     T   L
Sbjct: 1178 TNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNL 1237

Query: 1329 EPGIDYDISVITLINGGESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTN 1388
             PG++Y++SV T+ +  ES P + T   AVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTN
Sbjct: 1238 SPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTN 1297

Query: 1389 FLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTG 1448
            FLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTG
Sbjct: 1298 FLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTG 1357

Query: 1449 LDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTN 1508
            LDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTN
Sbjct: 1358 LDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTN 1417

Query: 1509 LTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRY 1568
            LTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRY
Sbjct: 1418 LTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRY 1477

Query: 1569 YRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISIN 1628
            YRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISIN
Sbjct: 1478 YRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISIN 1537

Query: 1629 YRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEM 1688
            YRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEM
Sbjct: 1538 YRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEM 1597

Query: 1689 TIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQG 1748
            TIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQG
Sbjct: 1598 TIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQG 1657

Query: 1749 QVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGT 1808
            QVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGT
Sbjct: 1658 QVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGT 1717

Query: 1809 QSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSV 1868
            QSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSV
Sbjct: 1718 QSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSV 1777

Query: 1869 VVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTK 1928
            VVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTK
Sbjct: 1778 VVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTK 1837

Query: 1929 TETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVI 1988
            TETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVI
Sbjct: 1838 TETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVI 1897

Query: 1989 DASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTE 2048
            DASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTE
Sbjct: 1898 DASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTE 1957

Query: 2049 ATITGLEPGTEYTIYVIALKNNQKSEPLIGRKK-------------------------TV 2083
            ATITGLEPGTEYTIYVIALKNNQKSEPLIGRKK                         TV
Sbjct: 1958 ATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELPQLVTLPHPNLHGPEILDVPSTV 2017

Query: 2084 QKTPFVTHPGYDTGNGIQLPGTSGQQPSVGQQMIFEEHGFRRTTPPTTATPIRHRPRPYP 2143
            QKTPFVTHPGYDTGNGIQLPGTSGQQPSVGQQMIFEEHGFRRTTPPTTATPIRHRPRPYP
Sbjct: 2018 QKTPFVTHPGYDTGNGIQLPGTSGQQPSVGQQMIFEEHGFRRTTPPTTATPIRHRPRPYP 2077

Query: 2144 PNVGQEALSQTTISWAPFQDTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATY 2203
            PNVGQEALSQTTISWAPFQDTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATY
Sbjct: 2078 PNVGQEALSQTTISWAPFQDTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATY 2137

Query: 2204 NIIVEALKDQQRHKVREEVVTVGNSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESG 2263
            NIIVEALKDQQRHKVREEVVTVGNSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESG
Sbjct: 2138 NIIVEALKDQQRHKVREEVVTVGNSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESG 2197

Query: 2264 FKLLCQCLGFGSGHFRCDSSRWCHDNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKC 2323
            FKLLCQCLGFGSGHFRCDSSRWCHDNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKC
Sbjct: 2198 FKLLCQCLGFGSGHFRCDSSRWCHDNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKC 2257

Query: 2324 DPHEATCYDDGKTYHVGEQWQKEYLGAICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQ 2383
            DPHEATCYDDGKTYHVGEQWQKEYLGAICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQ
Sbjct: 2258 DPHEATCYDDGKTYHVGEQWQKEYLGAICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQ 2317

Query: 2384 SYNQYSQRYHQRTNTNVNCPIECFMPLDVQADREDSRE 2421
            SYNQYSQRYHQRTNTNVNCPIECFMPLDVQADREDSRE
Sbjct: 2318 SYNQYSQRYHQRTNTNVNCPIECFMPLDVQADREDSRE 2355



 Score =  115 bits (287), Expect = 7e-25
 Identities = 57/129 (44%), Positives = 74/129 (57%), Gaps = 5/129 (3%)

Query: 2238 DDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHDNGVNYKIGE 2297
            +++CFD YT + Y VGD +ER  +S     C C+G G G   C  +  CH+ G +YKIG+
Sbjct: 94   EETCFDKYTGNTYRVGDTYERPKDSMI-WDCTCIGAGRGRISCTIANRCHEGGQSYKIGD 152

Query: 2298 KWDRQGE-NGQMMSCTCLGNGKGEFKCDPHEATCYDD--GKTYHVGEQWQKEYLG-AICS 2353
             W R  E  G M+ C CLGNGKGE+ C P    C+D   G +Y VGE W+K Y G  +  
Sbjct: 153  TWRRPHETGGYMLECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQGWMMVD 212

Query: 2354 CTCFGGQRG 2362
            CTC G   G
Sbjct: 213  CTCLGEGSG 221



 Score =  115 bits (287), Expect = 7e-25
 Identities = 57/129 (44%), Positives = 74/129 (57%), Gaps = 5/129 (3%)

Query: 94   EETCFDKYTGNTYRVGDTYERPKDSMI-WDCTCIGAGRGRISCTIANRCHEGGQSYKIGD 152
            +++CFD YT + Y VGD +ER  +S     C C+G G G   C  +  CH+ G +YKIG+
Sbjct: 2172 DDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHDNGVNYKIGE 2231

Query: 153  TWRRPHETGGYMLECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQGWMMVD 212
             W R  E  G M+ C CLGNGKGE+ C P    C+D   G +Y VGE W+K Y G  +  
Sbjct: 2232 KWDRQGE-NGQMMSCTCLGNGKGEFKCDPHEATCYDD--GKTYHVGEQWQKEYLG-AICS 2287

Query: 213  CTCLGEGSG 221
            CTC G   G
Sbjct: 2288 CTCFGGQRG 2296



 Score = 98.6 bits (244), Expect = 7e-20
 Identities = 54/172 (31%), Positives = 73/172 (42%), Gaps = 34/172 (19%)

Query: 2221 EVVTVGNSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRC 2280
            E V +GN   E   +P  + CFD    + Y VG+ WE+  +    + C CLG GSG   C
Sbjct: 166  ECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITC 225

Query: 2281 DSSRWCHDNG--VNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPH------------ 2326
             S   C+D     +Y+IG+ W ++   G ++ C C GNG+GE+KC+ H            
Sbjct: 226  TSRNRCNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGP 285

Query: 2327 ----EATCY----------------DDGKTYHVGEQWQKEYLGAICSCTCFG 2358
                 A  Y                D G  Y VG QW K        CTC G
Sbjct: 286  FTDVRAAVYQPQPHPQPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLG 337



 Score = 98.6 bits (244), Expect = 7e-20
 Identities = 54/172 (31%), Positives = 73/172 (42%), Gaps = 34/172 (19%)

Query: 166  ECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITC 225
            E V +GN   E   +P  + CFD    + Y VG+ WE+  +    + C CLG GSG   C
Sbjct: 2155 EVVTVGNSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRC 2214

Query: 226  TSRNRCNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGP 285
             S   C+D     +Y+IG+ W ++   G ++ C C GNG+GE+KC+ H            
Sbjct: 2215 DSSRWCHDNG--VNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPH------------ 2260

Query: 286  FTDVRAAVYQPQPHPQPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLG 337
                 A  Y                D G  Y VG QW K        CTC G
Sbjct: 2261 ----EATCY----------------DDGKTYHVGEQWQKEYLGAICSCTCFG 2292



 Score = 90.9 bits (224), Expect = 1e-17
 Identities = 40/123 (32%), Positives = 65/123 (52%), Gaps = 8/123 (6%)

Query: 2250 YAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHD----NGVNYKIGEKWDRQGEN 2305
            Y +GD+W++  + G  + C C+G G G + C +     D    + + Y + + + ++ E 
Sbjct: 478  YRIGDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEE 537

Query: 2306 GQMMSCTCLGNGKGEFKCDPHEATCYDD--GKTYHVGEQWQKEYLGAICSCTCFG-GQRG 2362
            G M++CTC G G+G +KCDP +  C D   G  Y +G+ W+K   G    C C+G G   
Sbjct: 538  GHMLNCTCFGQGRGRWKCDPVD-QCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGE 596

Query: 2363 WRC 2365
            W C
Sbjct: 597  WHC 599



 Score = 90.9 bits (224), Expect = 1e-17
 Identities = 40/123 (32%), Positives = 65/123 (52%), Gaps = 8/123 (6%)

Query: 478  YRIGDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEE 537
            Y +GD+W++  + G  + C C+G G G + C +     D    + + Y + + + ++ E 
Sbjct: 2184 YAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHD----NGVNYKIGEKWDRQGEN 2239

Query: 538  GHMLNCTCFGQGRGRWKCDPVD-QCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGE 596
            G M++CTC G G+G +KCDP +  C D   G  Y +G+ W+K   G    C C+G G   
Sbjct: 2240 GQMMSCTCLGNGKGEFKCDPHEATCYDD--GKTYHVGEQWQKEYLGAICSCTCFG-GQRG 2296

Query: 597  WHC 599
            W C
Sbjct: 2297 WRC 2299



 Score = 88.2 bits (217), Expect = 9e-17
 Identities = 45/124 (36%), Positives = 65/124 (52%), Gaps = 7/124 (5%)

Query: 2250 YAVGDEWERMSESG-FKLLCQCLGFGSGHFRCDS-SRWCHDN--GVNYKIGEKWDRQGEN 2305
            Y +GD W R  E+G + L C CLG G G + C   +  C D+  G +Y +GE W++  + 
Sbjct: 148  YKIGDTWRRPHETGGYMLECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQG 207

Query: 2306 GQMMSCTCLGNGKGEFKCDPHEATCYDDGKT-YHVGEQW-QKEYLGAICSCTCFGGQRG- 2362
              M+ CTCLG G G   C         D +T Y +G+ W +K+  G +  C C G  RG 
Sbjct: 208  WMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGE 267

Query: 2363 WRCD 2366
            W+C+
Sbjct: 268  WKCE 271



 Score = 88.2 bits (217), Expect = 9e-17
 Identities = 45/124 (36%), Positives = 65/124 (52%), Gaps = 7/124 (5%)

Query: 148  YKIGDTWRRPHETGGYMLECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQG 207
            Y +GD W R  E+G + L C CLG G G + C   +  C D+  G +Y +GE W++  + 
Sbjct: 2184 YAVGDEWERMSESG-FKLLCQCLGFGSGHFRCDS-SRWCHDN--GVNYKIGEKWDRQGEN 2239

Query: 208  WMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGE 267
              M+ CTCLG G G   C         D +T Y +G+ W +K+  G +  C C G  RG 
Sbjct: 2240 GQMMSCTCLGNGKGEFKCDPHEATCYDDGKT-YHVGEQW-QKEYLGAICSCTCFGGQRG- 2296

Query: 268  WKCE 271
            W+C+
Sbjct: 2297 WRCD 2300



 Score = 79.7 bits (195), Expect = 3e-14
 Identities = 37/84 (44%), Positives = 54/84 (64%), Gaps = 5/84 (5%)

Query: 2288 DNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEA---TCYDDGKTYHVGEQWQ 2344
            + GV Y+IG++WD+Q + G MM CTC+GNG+GE+ C  +      C  D  TY+V + + 
Sbjct: 473  NEGVMYRIGDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFH 532

Query: 2345 KEY-LGAICSCTCFGGQRG-WRCD 2366
            K +  G + +CTCFG  RG W+CD
Sbjct: 533  KRHEEGHMLNCTCFGQGRGRWKCD 556



 Score = 79.7 bits (195), Expect = 3e-14
 Identities = 37/84 (44%), Positives = 54/84 (64%), Gaps = 5/84 (5%)

Query: 473  NEGVMYRIGDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFH 532
            + GV Y+IG++WD+Q + G MM CTC+GNG+GE+ C  +      C  D  TY+V + + 
Sbjct: 2222 DNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEA---TCYDDGKTYHVGEQWQ 2278

Query: 533  KRHEEGHMLNCTCFGQGRGRWKCD 556
            K +  G + +CTCFG  RG W+CD
Sbjct: 2279 KEY-LGAICSCTCFGGQRG-WRCD 2300



 Score = 63.5 bits (153), Expect = 2e-09
 Identities = 32/82 (39%), Positives = 46/82 (56%), Gaps = 7/82 (8%)

Query: 2286 CHDNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPH---EATCYD--DGKTYHVG 2340
            C+DNG +Y+I ++W+R    G  + CTC G  +G F C+     E TC+D   G TY VG
Sbjct: 52   CYDNGKHYQINQQWERT-YLGNALVCTCYGGSRG-FNCESKPEAEETCFDKYTGNTYRVG 109

Query: 2341 EQWQKEYLGAICSCTCFGGQRG 2362
            + +++     I  CTC G  RG
Sbjct: 110  DTYERPKDSMIWDCTCIGAGRG 131



 Score = 63.5 bits (153), Expect = 2e-09
 Identities = 32/82 (39%), Positives = 46/82 (56%), Gaps = 7/82 (8%)

Query: 52   CYDNGKHYQINQQWERT-YLGNALVCTCYGGSRG-FNCESKPEAEETCFDKYTGNTYRVG 109
            C+DNG +Y+I ++W+R    G  + CTC G  +G F C+     E TC+D   G TY VG
Sbjct: 2220 CHDNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPH---EATCYD--DGKTYHVG 2274

Query: 110  DTYERPKDSMIWDCTCIGAGRG 131
            + +++     I  CTC G  RG
Sbjct: 2275 EQWQKEYLGAICSCTCFGGQRG 2296



 Score = 62.0 bits (149), Expect = 7e-09
 Identities = 37/107 (34%), Positives = 49/107 (45%), Gaps = 10/107 (9%)

Query: 2225 VGNSVNE----GLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRC 2280
            VGN   E      +Q  D    D  T   Y V D + +  E G  L C C G G G ++C
Sbjct: 499  VGNGRGEWTCIAYSQLRDQCIVDDIT---YNVNDTFHKRHEEGHMLNCTCFGQGRGRWKC 555

Query: 2281 DSSRWCHDN--GVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDP 2325
            D    C D+  G  Y+IG+ W++   +G    C C G G GE+ C P
Sbjct: 556  DPVDQCQDSETGTFYQIGDSWEKY-VHGVRYQCYCYGRGIGEWHCQP 601



 Score = 62.0 bits (149), Expect = 7e-09
 Identities = 37/107 (34%), Positives = 49/107 (45%), Gaps = 10/107 (9%)

Query: 499  VGNGRGEWTCIAYSQLRDQCIVDDIT---YNVNDTFHKRHEEGHMLNCTCFGQGRGRWKC 555
            VGN   E      +Q  D    D  T   Y V D + +  E G  L C C G G G ++C
Sbjct: 2159 VGNSVNE----GLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRC 2214

Query: 556  DPVDQCQDSETGTFYQIGDSWEKY-VHGVRYQCYCYGRGIGEWHCQP 601
            D    C D+  G  Y+IG+ W++   +G    C C G G GE+ C P
Sbjct: 2215 DSSRWCHDN--GVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDP 2259



 Score = 57.8 bits (138), Expect = 1e-07
 Identities = 24/62 (38%), Positives = 35/62 (56%), Gaps = 6/62 (9%)

Query: 2330 CYDDGKTYHVGEQWQKEYLGAICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYS 2389
            CYD+GK Y + +QW++ YLG    CTC+GG RG+ C++      +P  E T    Y   +
Sbjct: 52   CYDNGKHYQINQQWERTYLGNALVCTCYGGSRGFNCES------KPEAEETCFDKYTGNT 105

Query: 2390 QR 2391
             R
Sbjct: 106  YR 107



 Score = 57.8 bits (138), Expect = 1e-07
 Identities = 24/62 (38%), Positives = 35/62 (56%), Gaps = 6/62 (9%)

Query: 52   CYDNGKHYQINQQWERTYLGNALVCTCYGGSRGFNCES------KPEAEETCFDKYTGNT 105
            CYD+GK Y + +QW++ YLG    CTC+GG RG+ C++      +P  E T    Y   +
Sbjct: 2264 CYDDGKTYHVGEQWQKEYLGAICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYS 2323

Query: 106  YR 107
             R
Sbjct: 2324 QR 2325



 Score = 50.1 bits (118), Expect = 3e-05
 Identities = 31/110 (28%), Positives = 42/110 (38%), Gaps = 34/110 (30%)

Query: 2241 CFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDS------------------ 2282
            C D  T + Y +GD W +    G  L C C G G G ++C+                   
Sbjct: 231  CNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVR 290

Query: 2283 ---------------SRWCHDNGVNYKIGEKWDRQGENGQMMSCTCLGNG 2317
                                D+GV Y +G +W +   N QM+ CTCLGNG
Sbjct: 291  AAVYQPQPHPQPPPYGHCVTDSGVVYSVGMQWLKTQGNKQML-CTCLGNG 339



 Score = 50.1 bits (118), Expect = 3e-05
 Identities = 31/110 (28%), Positives = 42/110 (38%), Gaps = 34/110 (30%)

Query: 231  CNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVR 290
            C D  T + Y +GD W +    G  L C C G G G ++C+                   
Sbjct: 2175 CFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDS------------------ 2216

Query: 291  AAVYQPQPHPQPPPYGHCVTDSGVVYSVGMQWLKTQGNKQML-CTCLGNG 339
                                D+GV Y +G +W +   N QM+ CTCLGNG
Sbjct: 2217 ---------------SRWCHDNGVNYKIGEKWDRQGENGQMMSCTCLGNG 2251



 Score = 47.8 bits (112), Expect = 1e-04
 Identities = 79/335 (23%), Positives = 121/335 (36%), Gaps = 69/335 (20%)

Query: 1949 QRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVID---ASTAIDAPSNLRFLAT 2005
            + TI   + SYTI GL+PG  Y+  L ++           D    ST+    SN     T
Sbjct: 656  EATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGET 715

Query: 2006 TP----------------NSLLVSWQPPRARITGYIIKYE--KPGSPPREV-VPRPRPGV 2046
            TP                +S +VSW      ++G+ ++YE  + G  P+ + +P      
Sbjct: 716  TPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPST---A 772

Query: 2047 TEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKT-------------VQKTPFVTH-- 2091
            T   I  L PG +Y + V  +  + +   ++   +T             V  T  V    
Sbjct: 773  TSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWS 832

Query: 2092 ------PGY---------DTGNGIQLPGT------SGQQPSVGQQM-IFEEHGFRRTTP- 2128
                   GY          +   + LP T      S  QP V   + I+     + +TP 
Sbjct: 833  RPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPV 892

Query: 2129 ----PTTATPIRHR-PRPYPPNVGQEALSQTTISWAPFQD-TSEYIISCHPVGTDEEPLQ 2182
                 TT TP     P P      +    + TI W P +   + Y +   PV    E  Q
Sbjct: 893  VIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQ 952

Query: 2183 FRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHK 2217
                  +T A +TGL+ G TY   V A+   +  K
Sbjct: 953  RLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESK 987



 Score = 32.7 bits (73), Expect = 4.4
 Identities = 29/126 (23%), Positives = 53/126 (42%), Gaps = 20/126 (15%)

Query: 670  GLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVT 729
            G +P V   GQ +  +++G +           T+ P T+  +     P+ P V   E+++
Sbjct: 2041 GQQPSV---GQQMIFEEHGFRR----------TTPPTTATPIRHRPRPYPPNVG-QEALS 2086

Query: 730  EITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVN 789
            + T     +SW    DT S + +        +EP    +P T+TS  +  L  G  Y + 
Sbjct: 2087 QTT-----ISWAPFQDT-SEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNII 2140

Query: 790  VYQISE 795
            V  + +
Sbjct: 2141 VEALKD 2146


>gi|47132553 fibronectin 1 isoform 5 preproprotein [Homo sapiens]
          Length = 2296

 Score = 2990 bits (7751), Expect = 0.0
 Identities = 1509/2120 (71%), Positives = 1652/2120 (77%), Gaps = 78/2120 (3%)

Query: 1    MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ 60
            MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ
Sbjct: 1    MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ 60

Query: 61   INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI 120
            INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI
Sbjct: 61   INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI 120

Query: 121  WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK 180
            WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK
Sbjct: 121  WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK 180

Query: 181  PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY 240
            PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY
Sbjct: 181  PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY 240

Query: 241  RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP 300
            RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP
Sbjct: 241  RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP 300

Query: 301  QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC 360
            QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC
Sbjct: 301  QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC 360

Query: 361  VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC 420
            VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC
Sbjct: 361  VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC 420

Query: 421  HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI 480
            HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI
Sbjct: 421  HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI 480

Query: 481  GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM 540
            GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM
Sbjct: 481  GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM 540

Query: 541  LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ 600
            LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ
Sbjct: 541  LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ 600

Query: 601  PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP 660
            PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP
Sbjct: 601  PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP 660

Query: 661  GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP 720
            GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP
Sbjct: 661  GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP 720

Query: 721  LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL 780
            LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL
Sbjct: 721  LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL 780

Query: 781  LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITG 840
            LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITG
Sbjct: 781  LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITG 840

Query: 841  YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG 900
            YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG
Sbjct: 841  YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG 900

Query: 901  TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT 960
            TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT
Sbjct: 901  TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT 960

Query: 961  FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP 1020
            FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP
Sbjct: 961  FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP 1020

Query: 1021 RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG 1080
            RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG
Sbjct: 1021 RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG 1080

Query: 1081 VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV 1140
            VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV
Sbjct: 1081 VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV 1140

Query: 1141 SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT 1200
            SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT
Sbjct: 1141 SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT 1200

Query: 1201 PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS 1260
            PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS
Sbjct: 1201 PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS 1260

Query: 1261 DTIIPEVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIFEDFVDSSV 1320
            DTIIP VP  TDL F +I   ++ + W P  S  +  + +          + E  +  S 
Sbjct: 1261 DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSD 1320

Query: 1321 GYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAP 1380
                +T L PG +Y +SV ++    ES P    Q+T +  PT + F++I  ++  V W  
Sbjct: 1321 NAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIA 1380

Query: 1381 PPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTP 1440
            P +  +T + +R+ P        E  +  S N++ LTNL PGTEYVVS+ ++  + ES  
Sbjct: 1381 PRA-TITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPL 1439

Query: 1441 LRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHS 1500
            L G+Q T  D P  ++    T  S  + W AP  T+  YRI +     +   +E  VP S
Sbjct: 1440 LIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGS 1499

Query: 1501 RNSITLTNLTPGTEYVVSIVALNGREESPL----LIGQQSTVSDVPRDLEVVAATPTSLL 1556
            +++ T++ L PG +Y +++ A+ GR +SP     +     T  D P  ++V      S+ 
Sbjct: 1500 KSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSIS 1559

Query: 1557 ISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRG 1616
            + W   +  V  YR+T     G  P +  T    ++  TI GL+P V+Y ++VYA    G
Sbjct: 1560 VKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSG 1619

Query: 1617 DSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPT 1676
            +    S+P+     T I  P+ ++ T V   S+S +W P +  +TGYRV  TPK   GP 
Sbjct: 1620 E----SQPLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPM 1675

Query: 1677 KTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPL--VQTAVTNIDRPKGLAFTDV 1734
            K     PD + + + GL    +Y VSVYA   +  S+P   V T + N+  P+    TD 
Sbjct: 1676 KEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDA 1735

Query: 1735 DVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVV 1794
               +I I+W +    ++ ++V  + P +G   +      +  +  + GL+PG++Y + + 
Sbjct: 1736 TETTITISWRTKTETITGFQVD-AVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLY 1794

Query: 1795 ALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTG 1854
             L+D+  S P++   STAI AP++L+F   TP SL   W PP  ++TGY ++    EK G
Sbjct: 1795 TLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKY---EKPG 1851

Query: 1855 -PMKEI--NLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLE-------- 1903
             P +E+     P  +   ++GL   T+Y + V ALK+   S P  G   T E        
Sbjct: 1852 SPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELPQLVTLP 1911

Query: 1904 --NVSPPRRARVTDATETTITISWRTKTETITGFQVDAV----PANGQ------------ 1945
              N+  P    V    + T  ++     +T  G Q+       P+ GQ            
Sbjct: 1912 HPNLHGPEILDVPSTVQKTPFVT-HPGYDTGNGIQLPGTSGQQPSVGQQMIFEEHGFRRT 1970

Query: 1946 ------TPIQ---RTIKPDVRSYTITGLQPGTDYKIYLYT----LNDNARSSPVVIDAST 1992
                  TPI+   R   P+V      G  P  D   +LY     LN NA +    +  +T
Sbjct: 1971 TPPTTATPIRHRPRPYPPNVGEEIQIGHIPREDVDYHLYPHGPGLNPNASTGQEALSQTT 2030

Query: 1993 AIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATIT 2052
                               +SW P +   + YII     G+    +  R     T AT+T
Sbjct: 2031 -------------------ISWAPFQ-DTSEYIISCHPVGTDEEPLQFRVPGTSTSATLT 2070

Query: 2053 GLEPGTEYTIYVIALKNNQK 2072
            GL  G  Y I V ALK+ Q+
Sbjct: 2071 GLTRGATYNIIVEALKDQQR 2090



 Score = 1637 bits (4240), Expect = 0.0
 Identities = 915/1688 (54%), Positives = 1097/1688 (64%), Gaps = 114/1688 (6%)

Query: 829  VRWSRPQ-APITGYRIVYSPSVE-GSSTELNLPETANSVTLSDLQPGVQYNITIYAVEE- 885
            ++W+ PQ + I+ Y + + P    G   E  +P   NS T+  L+PGV Y   + ++++ 
Sbjct: 628  IQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQY 687

Query: 886  -NQESTPVVIQQETTGTPRSDTVPSPRDLQF----------VEVTDVKVTIMWTPPESAV 934
             +QE T       +T TP +    +     F           E+T     + W      V
Sbjct: 688  GHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTV 747

Query: 935  TGYRVDVIPVNLPGEHGQRLPI-SRNTFAEVTGLSPGVTYYFKVFAVSH-GRESKPLTAQ 992
            +G+RV+   ++  G+  Q L + S  T   +  L PG  Y   V+ +S  G +S  L+  
Sbjct: 748  SGFRVEY-ELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTS 806

Query: 993  QTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYP 1052
            QTT  DAP +       D++++VRW+ P+A ITGYR+    +  G   + N+  + +   
Sbjct: 807  QTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVT 866

Query: 1053 LRNLQPASEYTVSLVAIKGNQES-PKATGVFTTLQPGSSIPPYN-----TEVTETTIVIT 1106
            L +LQP  +Y +++ A++ NQES P      TT  P S   P        EVT+  + I 
Sbjct: 867  LSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIM 926

Query: 1107 WTPAPRI--GFKLGVRPSQ--GGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQER 1162
            WTP      G+++ V P    G    R   S +    V+GL+PGV Y + +  +  G+E 
Sbjct: 927  WTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRE- 985

Query: 1163 DAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTP--DITGYRITTTPTNGQQGNS 1220
              P+  +  T L  PTNL      D+ VL V W   T P   ITGYR+T   T  ++G  
Sbjct: 986  SKPLTAQQTTKLDAPTNLQFVNETDSTVL-VRW---TPPRAQITGYRLTVGLT--RRGQP 1039

Query: 1221 LEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPEVPQLTDLSF-VDIT 1279
             +  V    S     NL P  EY VS+  +K ++ES   +       P  +   +  ++T
Sbjct: 1040 RQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVT 1099

Query: 1280 DSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVI 1339
            +++I + WTP   +  IG+++ V  +  G    E  V S  G   V+GL PG++Y  ++ 
Sbjct: 1100 ETTIVITWTP---APRIGFKLGVRPSQGGEAPRE--VTSDSGSIVVSGLTPGVEYVYTIQ 1154

Query: 1340 TLINGGE-SAPTTLTQQTAVPPPTDLRFTNIGPDT--MRVTWAPPPSIDLTNFLVRYSPV 1396
             L +G E  AP      T + PPT+L      PDT  + V+W    + D+T + +  +P 
Sbjct: 1155 VLRDGQERDAPIVNKVVTPLSPPTNLHL-EANPDTGVLTVSWERSTTPDITGYRITTTPT 1213

Query: 1397 KNEE-DVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGI 1455
              ++ +  E  +    ++    NL PG EY VSV +V +  ES P+       +  PT +
Sbjct: 1214 NGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDL 1273

Query: 1456 DFSDITANSFTVHWIAPRAT-ITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTE 1514
             F++I  ++  V W  P +  +T + +R+ P        E  +  S N++ LTNL PGTE
Sbjct: 1274 RFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTE 1333

Query: 1515 YVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYG 1574
            YVVS+ ++  + ES  L G+Q T  D P  ++    T  S  + W AP  T+  YRI + 
Sbjct: 1334 YVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHH 1393

Query: 1575 ETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEID 1634
                +   +E  VP S+++ T++ L PG +Y +++ A+ GR +SP      S    T  D
Sbjct: 1394 PEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQS----TVSD 1449

Query: 1635 KPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQ 1694
             P  ++V      S+ + W   +  V  YR+T     G  P +  T    ++  TI GL+
Sbjct: 1450 VPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLK 1509

Query: 1695 PTVEYVVSVYAQNPSGES----QPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQV 1750
            P V+Y ++VYA    G+S    +P+     T ID+P  +  TDV  +SI + W      V
Sbjct: 1510 PGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPV 1569

Query: 1751 SRYRVTYSSPEDGIHELFPAPDGEEDTA-ELQGLRPGSEYTVSVVALHDDMESQPLIGTQ 1809
            + YRVT ++P++G         G + T   ++GL+P  EY VSV A +   ESQPL+ T 
Sbjct: 1570 TGYRVT-TTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTA 1628

Query: 1810 STAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVV 1869
             T IPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVV
Sbjct: 1629 VTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVV 1688

Query: 1870 VSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKT 1929
            VSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKT
Sbjct: 1689 VSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKT 1748

Query: 1930 ETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVID 1989
            ETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVID
Sbjct: 1749 ETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVID 1808

Query: 1990 ASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEA 2049
            ASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEA
Sbjct: 1809 ASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEA 1868

Query: 2050 TITGLEPGTEYTIYVIALKNNQKSEPLIGRKKT-------------------------VQ 2084
            TITGLEPGTEYTIYVIALKNNQKSEPLIGRKKT                         VQ
Sbjct: 1869 TITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTDELPQLVTLPHPNLHGPEILDVPSTVQ 1928

Query: 2085 KTPFVTHPGYDTGNGIQLPGTSGQQPSVGQQMIFEEHGFRRTTPPTTATPIRHRPRPYPP 2144
            KTPFVTHPGYDTGNGIQLPGTSGQQPSVGQQMIFEEHGFRRTTPPTTATPIRHRPRPYPP
Sbjct: 1929 KTPFVTHPGYDTGNGIQLPGTSGQQPSVGQQMIFEEHGFRRTTPPTTATPIRHRPRPYPP 1988

Query: 2145 NVG-------------------------------QEALSQTTISWAPFQDTSEYIISCHP 2173
            NVG                               QEALSQTTISWAPFQDTSEYIISCHP
Sbjct: 1989 NVGEEIQIGHIPREDVDYHLYPHGPGLNPNASTGQEALSQTTISWAPFQDTSEYIISCHP 2048

Query: 2174 VGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHKVREEVVTVGNSVNEGL 2233
            VGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHKVREEVVTVGNSVNEGL
Sbjct: 2049 VGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHKVREEVVTVGNSVNEGL 2108

Query: 2234 NQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHDNGVNY 2293
            NQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHDNGVNY
Sbjct: 2109 NQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHDNGVNY 2168

Query: 2294 KIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEATCYDDGKTYHVGEQWQKEYLGAICS 2353
            KIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEATCYDDGKTYHVGEQWQKEYLGAICS
Sbjct: 2169 KIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEATCYDDGKTYHVGEQWQKEYLGAICS 2228

Query: 2354 CTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYSQRYHQRTNTNVNCPIECFMPLDVQ 2413
            CTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYSQRYHQRTNTNVNCPIECFMPLDVQ
Sbjct: 2229 CTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYSQRYHQRTNTNVNCPIECFMPLDVQ 2288

Query: 2414 ADREDSRE 2421
            ADREDSRE
Sbjct: 2289 ADREDSRE 2296



 Score =  115 bits (287), Expect = 7e-25
 Identities = 57/129 (44%), Positives = 74/129 (57%), Gaps = 5/129 (3%)

Query: 2238 DDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHDNGVNYKIGE 2297
            +++CFD YT + Y VGD +ER  +S     C C+G G G   C  +  CH+ G +YKIG+
Sbjct: 94   EETCFDKYTGNTYRVGDTYERPKDSMI-WDCTCIGAGRGRISCTIANRCHEGGQSYKIGD 152

Query: 2298 KWDRQGE-NGQMMSCTCLGNGKGEFKCDPHEATCYDD--GKTYHVGEQWQKEYLG-AICS 2353
             W R  E  G M+ C CLGNGKGE+ C P    C+D   G +Y VGE W+K Y G  +  
Sbjct: 153  TWRRPHETGGYMLECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQGWMMVD 212

Query: 2354 CTCFGGQRG 2362
            CTC G   G
Sbjct: 213  CTCLGEGSG 221



 Score =  115 bits (287), Expect = 7e-25
 Identities = 57/129 (44%), Positives = 74/129 (57%), Gaps = 5/129 (3%)

Query: 94   EETCFDKYTGNTYRVGDTYERPKDSMI-WDCTCIGAGRGRISCTIANRCHEGGQSYKIGD 152
            +++CFD YT + Y VGD +ER  +S     C C+G G G   C  +  CH+ G +YKIG+
Sbjct: 2113 DDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHDNGVNYKIGE 2172

Query: 153  TWRRPHETGGYMLECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQGWMMVD 212
             W R  E  G M+ C CLGNGKGE+ C P    C+D   G +Y VGE W+K Y G  +  
Sbjct: 2173 KWDRQGE-NGQMMSCTCLGNGKGEFKCDPHEATCYDD--GKTYHVGEQWQKEYLG-AICS 2228

Query: 213  CTCLGEGSG 221
            CTC G   G
Sbjct: 2229 CTCFGGQRG 2237



 Score = 98.6 bits (244), Expect = 7e-20
 Identities = 54/172 (31%), Positives = 73/172 (42%), Gaps = 34/172 (19%)

Query: 2221 EVVTVGNSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRC 2280
            E V +GN   E   +P  + CFD    + Y VG+ WE+  +    + C CLG GSG   C
Sbjct: 166  ECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITC 225

Query: 2281 DSSRWCHDNG--VNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPH------------ 2326
             S   C+D     +Y+IG+ W ++   G ++ C C GNG+GE+KC+ H            
Sbjct: 226  TSRNRCNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGP 285

Query: 2327 ----EATCY----------------DDGKTYHVGEQWQKEYLGAICSCTCFG 2358
                 A  Y                D G  Y VG QW K        CTC G
Sbjct: 286  FTDVRAAVYQPQPHPQPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLG 337



 Score = 98.6 bits (244), Expect = 7e-20
 Identities = 54/172 (31%), Positives = 73/172 (42%), Gaps = 34/172 (19%)

Query: 166  ECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITC 225
            E V +GN   E   +P  + CFD    + Y VG+ WE+  +    + C CLG GSG   C
Sbjct: 2096 EVVTVGNSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRC 2155

Query: 226  TSRNRCNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGP 285
             S   C+D     +Y+IG+ W ++   G ++ C C GNG+GE+KC+ H            
Sbjct: 2156 DSSRWCHDNG--VNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPH------------ 2201

Query: 286  FTDVRAAVYQPQPHPQPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLG 337
                 A  Y                D G  Y VG QW K        CTC G
Sbjct: 2202 ----EATCY----------------DDGKTYHVGEQWQKEYLGAICSCTCFG 2233



 Score = 90.9 bits (224), Expect = 1e-17
 Identities = 40/123 (32%), Positives = 65/123 (52%), Gaps = 8/123 (6%)

Query: 2250 YAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHD----NGVNYKIGEKWDRQGEN 2305
            Y +GD+W++  + G  + C C+G G G + C +     D    + + Y + + + ++ E 
Sbjct: 478  YRIGDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEE 537

Query: 2306 GQMMSCTCLGNGKGEFKCDPHEATCYDD--GKTYHVGEQWQKEYLGAICSCTCFG-GQRG 2362
            G M++CTC G G+G +KCDP +  C D   G  Y +G+ W+K   G    C C+G G   
Sbjct: 538  GHMLNCTCFGQGRGRWKCDPVD-QCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGE 596

Query: 2363 WRC 2365
            W C
Sbjct: 597  WHC 599



 Score = 90.9 bits (224), Expect = 1e-17
 Identities = 40/123 (32%), Positives = 65/123 (52%), Gaps = 8/123 (6%)

Query: 478  YRIGDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEE 537
            Y +GD+W++  + G  + C C+G G G + C +     D    + + Y + + + ++ E 
Sbjct: 2125 YAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHD----NGVNYKIGEKWDRQGEN 2180

Query: 538  GHMLNCTCFGQGRGRWKCDPVD-QCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGE 596
            G M++CTC G G+G +KCDP +  C D   G  Y +G+ W+K   G    C C+G G   
Sbjct: 2181 GQMMSCTCLGNGKGEFKCDPHEATCYDD--GKTYHVGEQWQKEYLGAICSCTCFG-GQRG 2237

Query: 597  WHC 599
            W C
Sbjct: 2238 WRC 2240



 Score = 88.2 bits (217), Expect = 9e-17
 Identities = 45/124 (36%), Positives = 65/124 (52%), Gaps = 7/124 (5%)

Query: 2250 YAVGDEWERMSESG-FKLLCQCLGFGSGHFRCDS-SRWCHDN--GVNYKIGEKWDRQGEN 2305
            Y +GD W R  E+G + L C CLG G G + C   +  C D+  G +Y +GE W++  + 
Sbjct: 148  YKIGDTWRRPHETGGYMLECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQG 207

Query: 2306 GQMMSCTCLGNGKGEFKCDPHEATCYDDGKT-YHVGEQW-QKEYLGAICSCTCFGGQRG- 2362
              M+ CTCLG G G   C         D +T Y +G+ W +K+  G +  C C G  RG 
Sbjct: 208  WMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGE 267

Query: 2363 WRCD 2366
            W+C+
Sbjct: 268  WKCE 271



 Score = 88.2 bits (217), Expect = 9e-17
 Identities = 45/124 (36%), Positives = 65/124 (52%), Gaps = 7/124 (5%)

Query: 148  YKIGDTWRRPHETGGYMLECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQG 207
            Y +GD W R  E+G + L C CLG G G + C   +  C D+  G +Y +GE W++  + 
Sbjct: 2125 YAVGDEWERMSESG-FKLLCQCLGFGSGHFRCDS-SRWCHDN--GVNYKIGEKWDRQGEN 2180

Query: 208  WMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGE 267
              M+ CTCLG G G   C         D +T Y +G+ W +K+  G +  C C G  RG 
Sbjct: 2181 GQMMSCTCLGNGKGEFKCDPHEATCYDDGKT-YHVGEQW-QKEYLGAICSCTCFGGQRG- 2237

Query: 268  WKCE 271
            W+C+
Sbjct: 2238 WRCD 2241



 Score = 79.7 bits (195), Expect = 3e-14
 Identities = 37/84 (44%), Positives = 54/84 (64%), Gaps = 5/84 (5%)

Query: 2288 DNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEA---TCYDDGKTYHVGEQWQ 2344
            + GV Y+IG++WD+Q + G MM CTC+GNG+GE+ C  +      C  D  TY+V + + 
Sbjct: 473  NEGVMYRIGDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFH 532

Query: 2345 KEY-LGAICSCTCFGGQRG-WRCD 2366
            K +  G + +CTCFG  RG W+CD
Sbjct: 533  KRHEEGHMLNCTCFGQGRGRWKCD 556



 Score = 79.7 bits (195), Expect = 3e-14
 Identities = 37/84 (44%), Positives = 54/84 (64%), Gaps = 5/84 (5%)

Query: 473  NEGVMYRIGDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFH 532
            + GV Y+IG++WD+Q + G MM CTC+GNG+GE+ C  +      C  D  TY+V + + 
Sbjct: 2163 DNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEA---TCYDDGKTYHVGEQWQ 2219

Query: 533  KRHEEGHMLNCTCFGQGRGRWKCD 556
            K +  G + +CTCFG  RG W+CD
Sbjct: 2220 KEY-LGAICSCTCFGGQRG-WRCD 2241



 Score = 63.5 bits (153), Expect = 2e-09
 Identities = 32/82 (39%), Positives = 46/82 (56%), Gaps = 7/82 (8%)

Query: 2286 CHDNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPH---EATCYD--DGKTYHVG 2340
            C+DNG +Y+I ++W+R    G  + CTC G  +G F C+     E TC+D   G TY VG
Sbjct: 52   CYDNGKHYQINQQWERT-YLGNALVCTCYGGSRG-FNCESKPEAEETCFDKYTGNTYRVG 109

Query: 2341 EQWQKEYLGAICSCTCFGGQRG 2362
            + +++     I  CTC G  RG
Sbjct: 110  DTYERPKDSMIWDCTCIGAGRG 131



 Score = 63.5 bits (153), Expect = 2e-09
 Identities = 32/82 (39%), Positives = 46/82 (56%), Gaps = 7/82 (8%)

Query: 52   CYDNGKHYQINQQWERT-YLGNALVCTCYGGSRG-FNCESKPEAEETCFDKYTGNTYRVG 109
            C+DNG +Y+I ++W+R    G  + CTC G  +G F C+     E TC+D   G TY VG
Sbjct: 2161 CHDNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPH---EATCYD--DGKTYHVG 2215

Query: 110  DTYERPKDSMIWDCTCIGAGRG 131
            + +++     I  CTC G  RG
Sbjct: 2216 EQWQKEYLGAICSCTCFGGQRG 2237



 Score = 62.0 bits (149), Expect = 7e-09
 Identities = 37/107 (34%), Positives = 49/107 (45%), Gaps = 10/107 (9%)

Query: 2225 VGNSVNE----GLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRC 2280
            VGN   E      +Q  D    D  T   Y V D + +  E G  L C C G G G ++C
Sbjct: 499  VGNGRGEWTCIAYSQLRDQCIVDDIT---YNVNDTFHKRHEEGHMLNCTCFGQGRGRWKC 555

Query: 2281 DSSRWCHDN--GVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDP 2325
            D    C D+  G  Y+IG+ W++   +G    C C G G GE+ C P
Sbjct: 556  DPVDQCQDSETGTFYQIGDSWEKY-VHGVRYQCYCYGRGIGEWHCQP 601



 Score = 62.0 bits (149), Expect = 7e-09
 Identities = 37/107 (34%), Positives = 49/107 (45%), Gaps = 10/107 (9%)

Query: 499  VGNGRGEWTCIAYSQLRDQCIVDDIT---YNVNDTFHKRHEEGHMLNCTCFGQGRGRWKC 555
            VGN   E      +Q  D    D  T   Y V D + +  E G  L C C G G G ++C
Sbjct: 2100 VGNSVNE----GLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRC 2155

Query: 556  DPVDQCQDSETGTFYQIGDSWEKY-VHGVRYQCYCYGRGIGEWHCQP 601
            D    C D+  G  Y+IG+ W++   +G    C C G G GE+ C P
Sbjct: 2156 DSSRWCHDN--GVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDP 2200



 Score = 57.8 bits (138), Expect = 1e-07
 Identities = 24/62 (38%), Positives = 35/62 (56%), Gaps = 6/62 (9%)

Query: 2330 CYDDGKTYHVGEQWQKEYLGAICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYS 2389
            CYD+GK Y + +QW++ YLG    CTC+GG RG+ C++      +P  E T    Y   +
Sbjct: 52   CYDNGKHYQINQQWERTYLGNALVCTCYGGSRGFNCES------KPEAEETCFDKYTGNT 105

Query: 2390 QR 2391
             R
Sbjct: 106  YR 107



 Score = 57.8 bits (138), Expect = 1e-07
 Identities = 24/62 (38%), Positives = 35/62 (56%), Gaps = 6/62 (9%)

Query: 52   CYDNGKHYQINQQWERTYLGNALVCTCYGGSRGFNCES------KPEAEETCFDKYTGNT 105
            CYD+GK Y + +QW++ YLG    CTC+GG RG+ C++      +P  E T    Y   +
Sbjct: 2205 CYDDGKTYHVGEQWQKEYLGAICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYS 2264

Query: 106  YR 107
             R
Sbjct: 2265 QR 2266



 Score = 50.1 bits (118), Expect = 3e-05
 Identities = 31/110 (28%), Positives = 42/110 (38%), Gaps = 34/110 (30%)

Query: 2241 CFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDS------------------ 2282
            C D  T + Y +GD W +    G  L C C G G G ++C+                   
Sbjct: 231  CNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVR 290

Query: 2283 ---------------SRWCHDNGVNYKIGEKWDRQGENGQMMSCTCLGNG 2317
                                D+GV Y +G +W +   N QM+ CTCLGNG
Sbjct: 291  AAVYQPQPHPQPPPYGHCVTDSGVVYSVGMQWLKTQGNKQML-CTCLGNG 339



 Score = 50.1 bits (118), Expect = 3e-05
 Identities = 31/110 (28%), Positives = 42/110 (38%), Gaps = 34/110 (30%)

Query: 231  CNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVR 290
            C D  T + Y +GD W +    G  L C C G G G ++C+                   
Sbjct: 2116 CFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDS------------------ 2157

Query: 291  AAVYQPQPHPQPPPYGHCVTDSGVVYSVGMQWLKTQGNKQML-CTCLGNG 339
                                D+GV Y +G +W +   N QM+ CTCLGNG
Sbjct: 2158 ---------------SRWCHDNGVNYKIGEKWDRQGENGQMMSCTCLGNG 2192


>gi|47132549 fibronectin 1 isoform 6 preproprotein [Homo sapiens]
          Length = 2176

 Score = 2989 bits (7749), Expect = 0.0
 Identities = 1479/1992 (74%), Positives = 1612/1992 (80%), Gaps = 32/1992 (1%)

Query: 1    MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ 60
            MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ
Sbjct: 1    MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ 60

Query: 61   INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI 120
            INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI
Sbjct: 61   INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI 120

Query: 121  WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK 180
            WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK
Sbjct: 121  WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK 180

Query: 181  PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY 240
            PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY
Sbjct: 181  PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY 240

Query: 241  RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP 300
            RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP
Sbjct: 241  RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP 300

Query: 301  QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC 360
            QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC
Sbjct: 301  QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC 360

Query: 361  VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC 420
            VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC
Sbjct: 361  VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC 420

Query: 421  HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI 480
            HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI
Sbjct: 421  HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI 480

Query: 481  GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM 540
            GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM
Sbjct: 481  GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM 540

Query: 541  LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ 600
            LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ
Sbjct: 541  LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ 600

Query: 601  PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP 660
            PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP
Sbjct: 601  PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIP 660

Query: 661  GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP 720
            GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP
Sbjct: 661  GHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSP 720

Query: 721  LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL 780
            LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL
Sbjct: 721  LVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL 780

Query: 781  LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITG 840
            LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITG
Sbjct: 781  LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITG 840

Query: 841  YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG 900
            YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG
Sbjct: 841  YRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG 900

Query: 901  TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT 960
            TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT
Sbjct: 901  TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT 960

Query: 961  FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP 1020
            FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP
Sbjct: 961  FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP 1020

Query: 1021 RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG 1080
            RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG
Sbjct: 1021 RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG 1080

Query: 1081 VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV 1140
            VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV
Sbjct: 1081 VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVV 1140

Query: 1141 SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT 1200
            SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT
Sbjct: 1141 SGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT 1200

Query: 1201 PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS 1260
            PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS
Sbjct: 1201 PDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS 1260

Query: 1261 DTIIPEVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIFEDFVDSSV 1320
            DTIIP VP  TDL F +I   ++ + W P  S  +  + +          + E  +  S 
Sbjct: 1261 DTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSD 1320

Query: 1321 GYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAP 1380
                +T L PG +Y +SV ++    ES P    Q+T +  PT + F++I  ++  V W  
Sbjct: 1321 NAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIA 1380

Query: 1381 PPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTP 1440
            P +  +T + +R+ P        E  +  S N++ LTNL PGTEYVVS+ ++  + ES  
Sbjct: 1381 PRA-TITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPL 1439

Query: 1441 LRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHS 1500
            L G+Q T  D P  ++    T  S  + W AP  T+  YRI +     +   +E  VP S
Sbjct: 1440 LIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGS 1499

Query: 1501 RNSITLTNLTPGTEYVVSIVALNGREESPL----LIGQQSTVSDVPRDLEVVAATPTSLL 1556
            +++ T++ L PG +Y +++ A+ GR +SP     +     T  D P  ++V      S+ 
Sbjct: 1500 KSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSIS 1559

Query: 1557 ISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRG 1616
            + W   +  V  YR+T     G  P +  T    ++  TI GL+P V+Y ++VYA    G
Sbjct: 1560 VKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSG 1619

Query: 1617 DSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPT 1676
            +    S+P+     T I  P+ ++ T V   S+S +W P +  +TGYRV  TPK   GP 
Sbjct: 1620 E----SQPLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPM 1675

Query: 1677 KTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPL--VQTAVTNIDRPKGLAFTDV 1734
            K     PD + + + GL    +Y VSVYA   +  S+P   V T + N+  P+    TD 
Sbjct: 1676 KEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDA 1735

Query: 1735 DVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVV 1794
               +I I+W +    ++ ++V  + P +G   +      +  +  + GL+PG++Y + + 
Sbjct: 1736 TETTITISWRTKTETITGFQVD-AVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLY 1794

Query: 1795 ALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTG 1854
             L+D+  S P++   STAI AP++L+F   TP SL   W PP  ++TGY ++    EK G
Sbjct: 1795 TLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKY---EKPG 1851

Query: 1855 -PMKEI--NLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRA 1911
             P +E+     P  +   ++GL   T+Y + V ALK+   S P  G            R 
Sbjct: 1852 SPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIG------------RK 1899

Query: 1912 RVTDATETTITISWRTKTETITGFQVDAVP-ANGQTPIQRTIKPDVRSYTITGLQPGTDY 1970
            +      +  TISW    +T + + +   P    + P+Q  +     S T+TGL  G  Y
Sbjct: 1900 KTGQEALSQTTISWAPFQDT-SEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATY 1958

Query: 1971 KIYLYTLNDNAR 1982
             I +  L D  R
Sbjct: 1959 NIIVEALKDQQR 1970



 Score = 1077 bits (2785), Expect = 0.0
 Identities = 640/1349 (47%), Positives = 808/1349 (59%), Gaps = 81/1349 (6%)

Query: 768  LPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAP------------- 814
            +P    S  I  L PG  Y   +  I + G Q +      TT+   P             
Sbjct: 659  IPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPF 718

Query: 815  -----PDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTE-LNLPETANSVTLS 868
                    +V ++  +S VV W      ++G+R+ Y  S EG   + L+LP TA SV + 
Sbjct: 719  SPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIP 778

Query: 869  DLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWT 928
            DL PG +Y + +Y + E+ E + ++   +TT         +P D    +V D  + + W+
Sbjct: 779  DLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPD------APPDPTVDQVDDTSIVVRWS 832

Query: 929  PPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKP 988
             P++ +TGYR+   P          LP + N+   ++ L PGV Y   ++AV   +ES P
Sbjct: 833  RPQAPITGYRIVYSPSVEGSSTELNLPETANSVT-LSDLQPGVQYNITIYAVEENQESTP 891

Query: 989  LTAQQTTK-------LDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQ 1041
            +  QQ T        + +P +LQFV  TD  V + WTPP + +TGYR+ V       P +
Sbjct: 892  VVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDV--IPVNLPGE 949

Query: 1042 YNVGPSVSKYP---LRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEV 1098
            +     +S+     +  L P   Y   + A+   +ES   T   TT     +   +  E 
Sbjct: 950  HGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNE- 1008

Query: 1099 TETTIVITWTP--APRIGFKLGVRPSQGGEAPRE--VTSDSGSIVVSGLTPGVEYVYTIQ 1154
            T++T+++ WTP  A   G++L V  ++ G+ PR+  V        +  L P  EY  ++ 
Sbjct: 1009 TDSTVLVRWTPPRAQITGYRLTVGLTRRGQ-PRQYNVGPSVSKYPLRNLQPASEYTVSLV 1067

Query: 1155 VLRDGQERDAPIVNKVVTPLSPPTNL---HLEANPDTGVLTVSWERSTTPDITGYRITTT 1211
             ++  QE  +P    V T L P +++   + E    T V+T  W   T     G+++   
Sbjct: 1068 AIKGNQE--SPKATGVFTTLQPGSSIPPYNTEVTETTIVIT--W---TPAPRIGFKLGVR 1120

Query: 1212 PTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKE-SVPISDTIIPEVPQL 1270
            P+   QG      V +D  S     L+PG+EY  ++  ++D +E   PI + ++  +   
Sbjct: 1121 PS---QGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPP 1177

Query: 1271 TDLSFVDITDSSI-GLRWTPLNSSTIIGYRITVVAA-GEGIPIFEDFVDSSVGYYTVTGL 1328
            T+L      D+ +  + W    +  I GYRIT     G+     E+ V +     T   L
Sbjct: 1178 TNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNL 1237

Query: 1329 EPGIDYDISVITLINGGESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTN 1388
             PG++Y++SV T+ +  ES P + T   AVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTN
Sbjct: 1238 SPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTN 1297

Query: 1389 FLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTG 1448
            FLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTG
Sbjct: 1298 FLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTG 1357

Query: 1449 LDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTN 1508
            LDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTN
Sbjct: 1358 LDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTN 1417

Query: 1509 LTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRY 1568
            LTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRY
Sbjct: 1418 LTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRY 1477

Query: 1569 YRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISIN 1628
            YRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISIN
Sbjct: 1478 YRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISIN 1537

Query: 1629 YRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEM 1688
            YRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEM
Sbjct: 1538 YRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEM 1597

Query: 1689 TIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQG 1748
            TIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVT I  P  L FT V   S+   W  P  
Sbjct: 1598 TIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNV 1657

Query: 1749 QVSRYRVTYSSPEDG--IHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLI 1806
            Q++ YRV  +  E    + E+  APD    +  + GL   ++Y VSV AL D + S+P  
Sbjct: 1658 QLTGYRVRVTPKEKTGPMKEINLAPDSS--SVVVSGLMVATKYEVSVYALKDTLTSRPAQ 1715

Query: 1807 GTQSTA--IPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPD 1864
            G  +T   +  P   + T  T T+++  W      +TG++V   P     P++   + PD
Sbjct: 1716 GVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQR-TIKPD 1774

Query: 1865 SSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITIS 1924
              S  ++GL   T Y++ +Y L D   S P   V+     +  P   R    T  ++ +S
Sbjct: 1775 VRSYTITGLQPGTDYKIYLYTLNDNARSSPV--VIDASTAIDAPSNLRFLATTPNSLLVS 1832

Query: 1925 WRTKTETITGFQVD-AVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARS 1983
            W+     ITG+ +    P +    +    +P V   TITGL+PGT+Y IY+  L +N +S
Sbjct: 1833 WQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKS 1892

Query: 1984 SPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPR 2043
             P++    T  +A S      TT     +SW P +   + YII     G+    +  R  
Sbjct: 1893 EPLIGRKKTGQEALSQ-----TT-----ISWAPFQ-DTSEYIISCHPVGTDEEPLQFRVP 1941

Query: 2044 PGVTEATITGLEPGTEYTIYVIALKNNQK 2072
               T AT+TGL  G  Y I V ALK+ Q+
Sbjct: 1942 GTSTSATLTGLTRGATYNIIVEALKDQQR 1970



 Score = 1068 bits (2762), Expect = 0.0
 Identities = 693/1658 (41%), Positives = 904/1658 (54%), Gaps = 174/1658 (10%)

Query: 829  VRWSRPQ-APITGYRIVYSPSVE-GSSTELNLPETANSVTLSDLQPGVQYNITIYAVEE- 885
            ++W+ PQ + I+ Y + + P    G   E  +P   NS T+  L+PGV Y   + ++++ 
Sbjct: 628  IQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQY 687

Query: 886  -NQESTPVVIQQETTGTPRSDTVPSPRDLQF----------VEVTDVKVTIMWTPPESAV 934
             +QE T       +T TP +    +     F           E+T     + W      V
Sbjct: 688  GHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTV 747

Query: 935  TGYRVDVIPVNLPGEHGQRLPI-SRNTFAEVTGLSPGVTYYFKVFAVSH-GRESKPLTAQ 992
            +G+RV+   ++  G+  Q L + S  T   +  L PG  Y   V+ +S  G +S  L+  
Sbjct: 748  SGFRVEY-ELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTS 806

Query: 993  QTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYP 1052
            QTT  DAP +       D++++VRW+ P+A ITGYR+    +  G   + N+  + +   
Sbjct: 807  QTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVT 866

Query: 1053 LRNLQPASEYTVSLVAIKGNQES-PKATGVFTTLQPGSSIPPYN-----TEVTETTIVIT 1106
            L +LQP  +Y +++ A++ NQES P      TT  P S   P        EVT+  + I 
Sbjct: 867  LSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIM 926

Query: 1107 WTPAPRI--GFKLGVRPSQ--GGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQER 1162
            WTP      G+++ V P    G    R   S +    V+GL+PGV Y + +  +  G+E 
Sbjct: 927  WTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRE- 985

Query: 1163 DAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTP--DITGYRITTTPTNGQQGNS 1220
              P+  +  T L  PTNL      D+ VL V W   T P   ITGYR+T   T  ++G  
Sbjct: 986  SKPLTAQQTTKLDAPTNLQFVNETDSTVL-VRW---TPPRAQITGYRLTVGLT--RRGQP 1039

Query: 1221 LEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPEVPQLTDLSF-VDIT 1279
             +  V    S     NL P  EY VS+  +K ++ES   +       P  +   +  ++T
Sbjct: 1040 RQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVT 1099

Query: 1280 DSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVI 1339
            +++I + WTP   +  IG+++ V  +  G    E  V S  G   V+GL PG++Y  ++ 
Sbjct: 1100 ETTIVITWTP---APRIGFKLGVRPSQGGEAPRE--VTSDSGSIVVSGLTPGVEYVYTIQ 1154

Query: 1340 TLINGGE-SAPTTLTQQTAVPPPTDLRFTNIGPDT--MRVTWAPPPSIDLTNFLVRYSPV 1396
             L +G E  AP      T + PPT+L      PDT  + V+W    + D+T + +  +P 
Sbjct: 1155 VLRDGQERDAPIVNKVVTPLSPPTNLHL-EANPDTGVLTVSWERSTTPDITGYRITTTPT 1213

Query: 1397 KNEE-DVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGI 1455
              ++ +  E  +    ++    NL PG EY VSV +V +  ES P+       +  PT +
Sbjct: 1214 NGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPAVPPPTDL 1273

Query: 1456 DFSDITANSFTVHWIAPRAT-ITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTE 1514
             F++I  ++  V W  P +  +T + +R+ P        E  +  S N++ LTNL PGTE
Sbjct: 1274 RFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTE 1333

Query: 1515 YVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYG 1574
            YVVS+ ++  + ES  L G+Q T  D P  ++    T  S  + W AP  T+  YRI + 
Sbjct: 1334 YVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHH 1393

Query: 1575 ETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEID 1634
                +   +E  VP S+++ T++ L PG +Y +++ A+ GR +SP      S    T  D
Sbjct: 1394 PEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQS----TVSD 1449

Query: 1635 KPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQ 1694
             P  ++V      S+ + W   +  V  YR+T     G  P +  T    ++  TI GL+
Sbjct: 1450 VPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLK 1509

Query: 1695 PTVEYVVSVYAQNPSGES----QPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQV 1750
            P V+Y ++VYA    G+S    +P+     T ID+P  +  TDV  +SI + W      V
Sbjct: 1510 PGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPV 1569

Query: 1751 SRYRVTYSSPEDGIHELFPAPDGEEDTA-ELQGLRPGSEYTVSVVALHDDMESQPLIGTQ 1809
            + YRVT ++P++G         G + T   ++GL+P  EY VSV A +   ESQPL+ T 
Sbjct: 1570 TGYRVT-TTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTA 1628

Query: 1810 STAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVV 1869
             T IPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVV
Sbjct: 1629 VTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVV 1688

Query: 1870 VSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKT 1929
            VSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKT
Sbjct: 1689 VSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKT 1748

Query: 1930 ETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVID 1989
            ETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVID
Sbjct: 1749 ETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVID 1808

Query: 1990 ASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEA 2049
            ASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEA
Sbjct: 1809 ASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEA 1868

Query: 2050 TITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQ----KTPFVTHPGYDTGNGI----- 2100
            TITGLEPGTEYTIYVIALKNNQKSEPLIGRKKT Q    +T     P  DT   I     
Sbjct: 1869 TITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTGQEALSQTTISWAPFQDTSEYIISCHP 1928

Query: 2101 ----------QLPGTSGQQPSVGQQMIFEEHGFRRTTPPTTATPIRHRPRPYPPNVG--- 2147
                      ++PGTS      G                      RH+ R     VG   
Sbjct: 1929 VGTDEEPLQFRVPGTSTSATLTG----LTRGATYNIIVEALKDQQRHKVREEVVTVGNSV 1984

Query: 2148 QEALSQTTISWAPFQDT--SEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNI 2205
             E L+Q      P  D+    Y +S + VG + E +                   + + +
Sbjct: 1985 NEGLNQ------PTDDSCFDPYTVSHYAVGDEWERMS-----------------ESGFKL 2021

Query: 2206 IVEALKDQQRH-KVREEVVTVGNSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGF 2264
            + + L     H +         N VN  + +  D              G+  + MS    
Sbjct: 2022 LCQCLGFGSGHFRCDSSRWCHDNGVNYKIGEKWDRQ------------GENGQMMS---- 2065

Query: 2265 KLLCQCLGFGSGHFRCD-SSRWCHDNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKC 2323
               C CLG G G F+CD     C+D+G  Y +GE+W ++   G + SCTC G  +G    
Sbjct: 2066 ---CTCLGNGKGEFKCDPHEATCYDDGKTYHVGEQWQKE-YLGAICSCTCFGGQRG---- 2117

Query: 2324 DPHEATCYDDGKTYHVGEQWQKEYLGAICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQ 2383
                                                   WRCDNCRRPGGEPSPEGTTGQ
Sbjct: 2118 ---------------------------------------WRCDNCRRPGGEPSPEGTTGQ 2138

Query: 2384 SYNQYSQRYHQRTNTNVNCPIECFMPLDVQADREDSRE 2421
            SYNQYSQRYHQRTNTNVNCPIECFMPLDVQADREDSRE
Sbjct: 2139 SYNQYSQRYHQRTNTNVNCPIECFMPLDVQADREDSRE 2176



 Score =  494 bits (1273), Expect = e-139
 Identities = 359/1298 (27%), Positives = 593/1298 (45%), Gaps = 94/1298 (7%)

Query: 659  IPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPF 718
            +P    S  I  L PG  Y   +  I + G Q +      TT+   P             
Sbjct: 768  LPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAP------------- 814

Query: 719  SPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIP 778
                    +V ++  +S VV W      ++G+R+ Y  S EG   + L+LP TA SV + 
Sbjct: 815  -----PDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTE-LNLPETANSVTLS 868

Query: 779  DLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPD------APPDPTVDQVDDTSIVVRWS 832
            DL PG +Y + +Y + E+ E + ++   +TT         +P D    +V D  + + W+
Sbjct: 869  DLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWT 928

Query: 833  RPQAPITGYRIVYSPSVEGSSTELNLPETANSVT-LSDLQPGVQYNITIYAVEENQESTP 891
             P++ +TGYR+   P          LP + N+   ++ L PGV Y   ++AV   +ES P
Sbjct: 929  PPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKP 988

Query: 892  VVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHG 951
            +  QQ T        + +P +LQFV  TD  V + WTPP + +TGYR+ V      G   
Sbjct: 989  LTAQQTTK-------LDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTV------GLTR 1035

Query: 952  QRLPISRNTFAEVT-----GLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFV 1006
            +  P   N    V+      L P   Y   + A+   +ES   T   TT     +   + 
Sbjct: 1036 RGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYN 1095

Query: 1007 NE-TDSTVLVRWTPPRAQITGYRLTVGLTRRGQ-PRQYNVGPSVSKYPLRNLQPASEYTV 1064
             E T++T+++ WTP  A   G++L V  ++ G+ PR+  V        +  L P  EY  
Sbjct: 1096 TEVTETTIVITWTP--APRIGFKLGVRPSQGGEAPRE--VTSDSGSIVVSGLTPGVEYVY 1151

Query: 1065 SLVAIKGNQE--SPKATGVFTTLQPGSSIPPYNTEVTETTIVIT--W---TPAPRIGFKL 1117
            ++  ++  QE  +P    V T L P +++   + E    T V+T  W   T     G+++
Sbjct: 1152 TIQVLRDGQERDAPIVNKVVTPLSPPTNL---HLEANPDTGVLTVSWERSTTPDITGYRI 1208

Query: 1118 GVRPS---QGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPL 1174
               P+   QG      V +D  S     L+PG+EY  ++  ++D +E   PI + ++  +
Sbjct: 1209 TTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKE-SVPISDTIIPAV 1267

Query: 1175 SPPTNLHL-EANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCT 1233
             PPT+L      PDT  + V+W    + D+T + +  +P   ++ +  E  +    ++  
Sbjct: 1268 PPPTDLRFTNIGPDT--MRVTWAPPPSIDLTNFLVRYSPVKNEE-DVAELSISPSDNAVV 1324

Query: 1234 FDNLSPGLEYNVSVYTVKDDKESVPISDTIIPEVPQLTDLSFVDITDSSIGLRWTPLNSS 1293
              NL PG EY VSV +V +  ES P+       +   T + F DIT +S  + W    + 
Sbjct: 1325 LTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRA- 1383

Query: 1294 TIIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLT 1353
            TI GYRI            ED V  S    T+T L PG +Y +S++ L NG E +P  + 
Sbjct: 1384 TITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVAL-NGREESPLLIG 1442

Query: 1354 QQTAVPP-PTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDN 1412
            QQ+ V   P DL      P ++ ++W   P++ +  + + Y        V E ++  S +
Sbjct: 1443 QQSTVSDVPRDLEVVAATPTSLLISW-DAPAVTVRYYRITYGETGGNSPVQEFTVPGSKS 1501

Query: 1413 AVVLTNLLPGTEYVVSVSSVYEQHEST----PLRGRQKTGLDSPTGIDFSDITANSFTVH 1468
               ++ L PG +Y ++V +V  + +S     P+    +T +D P+ +  +D+  NS +V 
Sbjct: 1502 TATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVK 1561

Query: 1469 WIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREES 1528
            W+   + +TGYR+   P++  G  +       +  +T+  L P  EYVVS+ A N   ES
Sbjct: 1562 WLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGES 1621

Query: 1529 PLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVP 1588
              L+    T    P DL+    TPTSL   W  P V +  YR+         P++E  + 
Sbjct: 1622 QPLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLA 1681

Query: 1589 GSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPIS--INYRTEIDKPSQMQVTDVQD 1646
               S+  +SGL     Y ++VYA+        +S+P    +     +  P + +VTD  +
Sbjct: 1682 PDSSSVVVSGLMVATKYEVSVYALK----DTLTSRPAQGVVTTLENVSPPRRARVTDATE 1737

Query: 1647 NSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQ 1706
             +I++ W   +  +TG++V   P NG  P + +T  PD    TI GLQP  +Y + +Y  
Sbjct: 1738 TTITISWRTKTETITGFQVDAVPANGQTPIQ-RTIKPDVRSYTITGLQPGTDYKIYLYTL 1796

Query: 1707 NPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHE 1766
            N +  S P+V  A T ID P  L F     +S+ ++W+ P+ +++ Y + Y  P     E
Sbjct: 1797 NDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPRE 1856

Query: 1767 LFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTP 1826
            + P P      A + GL PG+EYT+ V+AL ++ +S+PLIG + T   A        ++ 
Sbjct: 1857 VVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTGQEA--------LSQ 1908

Query: 1827 TSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYAL 1886
            T++S  W P     + Y +   P        +  +   S+S  ++GL     Y + V AL
Sbjct: 1909 TTIS--WAPFQ-DTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEAL 1965

Query: 1887 KDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITIS 1924
            KD    +  + VVT   +V+        D+     T+S
Sbjct: 1966 KDQQRHKVREEVVTVGNSVNEGLNQPTDDSCFDPYTVS 2003



 Score =  417 bits (1073), Expect = e-116
 Identities = 354/1221 (28%), Positives = 545/1221 (44%), Gaps = 120/1221 (9%)

Query: 1089 SSIPPYNTEVTET-----TIVITWT---PAPRIGFKLGVRPSQGGEAPREVTSDS--GSI 1138
            SS  P    +TET     +  I W    P+    + L  RP       +E T      S 
Sbjct: 607  SSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSY 666

Query: 1139 VVSGLTPGVEYV-YTIQVLRDGQER-----------DAPIVNKVVTPLSPPTNLHLEANP 1186
             + GL PGV Y    I + + G +              P+ +  VT  + P +  +  + 
Sbjct: 667  TIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSE 726

Query: 1187 DTGVLT-----VSWERSTTPDITGYRIT-TTPTNGQQGNSLEEVVHADQSSCTFDNLSPG 1240
                +T     VSW  S +  ++G+R+       G +   L+  + +  +S    +L PG
Sbjct: 727  SVTEITASSFVVSWV-SASDTVSGFRVEYELSEEGDEPQYLD--LPSTATSVNIPDLLPG 783

Query: 1241 LEYNVSVYTVKDDKESVPI---SDTIIPEVPQLTDLSFVDITDSSIGLRWTPLNSSTIIG 1297
             +Y V+VY + +D E   I   S T  P+ P    +  VD  D+SI +RW+    + I G
Sbjct: 784  RKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVD--DTSIVVRWSR-PQAPITG 840

Query: 1298 YRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTA 1357
            YRI    + EG    E  +  +    T++ L+PG+ Y+I++  +    ES P  + Q+T 
Sbjct: 841  YRIVYSPSVEGSST-ELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETT 899

Query: 1358 -------VPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNE-EDVAELSISP 1409
                   VP P DL+F  +    + + W PP S  +T + V   PV    E    L IS 
Sbjct: 900  GTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESA-VTGYRVDVIPVNLPGEHGQRLPISR 958

Query: 1410 SDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHW 1469
            +  A V T L PG  Y   V +V    ES PL  +Q T LD+PT + F + T ++  V W
Sbjct: 959  NTFAEV-TGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRW 1017

Query: 1470 IAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESP 1529
              PRA ITGYR+        G+PR+  V  S +   L NL P +EY VS+VA+ G +ESP
Sbjct: 1018 TPPRAQITGYRLTVGLTR-RGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESP 1076

Query: 1530 LLIGQQSTV----SDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEF 1585
               G  +T+    S  P + EV   T T+++I+W  PA  + +        GG +P +  
Sbjct: 1077 KATGVFTTLQPGSSIPPYNTEV---TETTIVITW-TPAPRIGFKLGVRPSQGGEAPRE-- 1130

Query: 1586 TVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQ 1645
             V     +  +SGL PGV+Y  T+  +    D      PI     T +  P+ + +    
Sbjct: 1131 -VTSDSGSIVVSGLTPGVEYVYTIQVLR---DGQERDAPIVNKVVTPLSPPTNLHLEANP 1186

Query: 1646 DNSI-SVKWLPSSSP-VTGYRVTTTPKNGP-GPTKTKTAGPDQTEMTIEGLQPTVEYVVS 1702
            D  + +V W  S++P +TGYR+TTTP NG  G +  +    DQ+  T + L P +EY VS
Sbjct: 1187 DTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVS 1246

Query: 1703 VYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQG-QVSRYRVTYS--S 1759
            VY      ES P+  T +  +  P  L FT++  D++++ W  P    ++ + V YS   
Sbjct: 1247 VYTVKDDKESVPISDTIIPAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVK 1306

Query: 1760 PEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDL 1819
             E+ + EL  +P   ++   L  L PG+EY VSV ++++  ES PL G Q T + +PT +
Sbjct: 1307 NEEDVAELSISPS--DNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGI 1364

Query: 1820 KFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKY 1879
             F+ +T  S +  W  P   +TGYR+R  P+  +G  +E  +    +S+ ++ L   T+Y
Sbjct: 1365 DFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEY 1424

Query: 1880 EVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDA 1939
             VS+ AL     S    G  +T+ +V  PR   V  AT T++ ISW     T+  +++  
Sbjct: 1425 VVSIVALNGREESPLLIGQQSTVSDV--PRDLEVVAATPTSLLISWDAPAVTVRYYRITY 1482

Query: 1940 VPANGQTPIQRTIKPDVRSY-TITGLQPGTDYKIYLYTLNDN----ARSSPVVIDASTAI 1994
                G +P+Q    P  +S  TI+GL+PG DY I +Y +       A S P+ I+  T I
Sbjct: 1483 GETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEI 1542

Query: 1995 DAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGL 2054
            D PS ++      NS+ V W P  + +TGY +       P         P  TE TI GL
Sbjct: 1543 DKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGL 1602

Query: 2055 EPGTEYTIYVIALKNNQKSEPLIGRK----------KTVQKTPFVTHPGYDTGNGIQLPG 2104
            +P  EY + V A   + +S+PL+             K  Q TP      +   N +QL G
Sbjct: 1603 QPTVEYVVSVYAQNPSGESQPLVQTAVTTIPAPTDLKFTQVTPTSLSAQWTPPN-VQLTG 1661

Query: 2105 ---------------------------TSGQQPSVGQQMIFEEHGFRRTTPPT--TATPI 2135
                                        SG   +   ++         T+ P     T +
Sbjct: 1662 YRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTL 1721

Query: 2136 RHRPRPYPPNVGQEALSQTTISWAPFQDT-SEYIISCHPVGTDEEPLQFRVPGTSTSATL 2194
             +   P    V     +  TISW    +T + + +   P    + P+Q  +     S T+
Sbjct: 1722 ENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVP-ANGQTPIQRTIKPDVRSYTI 1780

Query: 2195 TGLTRGATYNIIVEALKDQQR 2215
            TGL  G  Y I +  L D  R
Sbjct: 1781 TGLQPGTDYKIYLYTLNDNAR 1801



 Score =  115 bits (287), Expect = 7e-25
 Identities = 57/129 (44%), Positives = 74/129 (57%), Gaps = 5/129 (3%)

Query: 2238 DDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHDNGVNYKIGE 2297
            +++CFD YT + Y VGD +ER  +S     C C+G G G   C  +  CH+ G +YKIG+
Sbjct: 94   EETCFDKYTGNTYRVGDTYERPKDSMI-WDCTCIGAGRGRISCTIANRCHEGGQSYKIGD 152

Query: 2298 KWDRQGE-NGQMMSCTCLGNGKGEFKCDPHEATCYDD--GKTYHVGEQWQKEYLG-AICS 2353
             W R  E  G M+ C CLGNGKGE+ C P    C+D   G +Y VGE W+K Y G  +  
Sbjct: 153  TWRRPHETGGYMLECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQGWMMVD 212

Query: 2354 CTCFGGQRG 2362
            CTC G   G
Sbjct: 213  CTCLGEGSG 221



 Score =  115 bits (287), Expect = 7e-25
 Identities = 57/129 (44%), Positives = 74/129 (57%), Gaps = 5/129 (3%)

Query: 94   EETCFDKYTGNTYRVGDTYERPKDSMI-WDCTCIGAGRGRISCTIANRCHEGGQSYKIGD 152
            +++CFD YT + Y VGD +ER  +S     C C+G G G   C  +  CH+ G +YKIG+
Sbjct: 1993 DDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHDNGVNYKIGE 2052

Query: 153  TWRRPHETGGYMLECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQGWMMVD 212
             W R  E  G M+ C CLGNGKGE+ C P    C+D   G +Y VGE W+K Y G  +  
Sbjct: 2053 KWDRQGE-NGQMMSCTCLGNGKGEFKCDPHEATCYDD--GKTYHVGEQWQKEYLG-AICS 2108

Query: 213  CTCLGEGSG 221
            CTC G   G
Sbjct: 2109 CTCFGGQRG 2117



 Score = 98.6 bits (244), Expect = 7e-20
 Identities = 54/172 (31%), Positives = 73/172 (42%), Gaps = 34/172 (19%)

Query: 2221 EVVTVGNSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRC 2280
            E V +GN   E   +P  + CFD    + Y VG+ WE+  +    + C CLG GSG   C
Sbjct: 166  ECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITC 225

Query: 2281 DSSRWCHDNG--VNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPH------------ 2326
             S   C+D     +Y+IG+ W ++   G ++ C C GNG+GE+KC+ H            
Sbjct: 226  TSRNRCNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGP 285

Query: 2327 ----EATCY----------------DDGKTYHVGEQWQKEYLGAICSCTCFG 2358
                 A  Y                D G  Y VG QW K        CTC G
Sbjct: 286  FTDVRAAVYQPQPHPQPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLG 337



 Score = 98.6 bits (244), Expect = 7e-20
 Identities = 54/172 (31%), Positives = 73/172 (42%), Gaps = 34/172 (19%)

Query: 166  ECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITC 225
            E V +GN   E   +P  + CFD    + Y VG+ WE+  +    + C CLG GSG   C
Sbjct: 1976 EVVTVGNSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRC 2035

Query: 226  TSRNRCNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGP 285
             S   C+D     +Y+IG+ W ++   G ++ C C GNG+GE+KC+ H            
Sbjct: 2036 DSSRWCHDNG--VNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPH------------ 2081

Query: 286  FTDVRAAVYQPQPHPQPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLG 337
                 A  Y                D G  Y VG QW K        CTC G
Sbjct: 2082 ----EATCY----------------DDGKTYHVGEQWQKEYLGAICSCTCFG 2113



 Score = 90.9 bits (224), Expect = 1e-17
 Identities = 40/123 (32%), Positives = 65/123 (52%), Gaps = 8/123 (6%)

Query: 2250 YAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHD----NGVNYKIGEKWDRQGEN 2305
            Y +GD+W++  + G  + C C+G G G + C +     D    + + Y + + + ++ E 
Sbjct: 478  YRIGDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEE 537

Query: 2306 GQMMSCTCLGNGKGEFKCDPHEATCYDD--GKTYHVGEQWQKEYLGAICSCTCFG-GQRG 2362
            G M++CTC G G+G +KCDP +  C D   G  Y +G+ W+K   G    C C+G G   
Sbjct: 538  GHMLNCTCFGQGRGRWKCDPVD-QCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGE 596

Query: 2363 WRC 2365
            W C
Sbjct: 597  WHC 599



 Score = 90.9 bits (224), Expect = 1e-17
 Identities = 40/123 (32%), Positives = 65/123 (52%), Gaps = 8/123 (6%)

Query: 478  YRIGDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEE 537
            Y +GD+W++  + G  + C C+G G G + C +     D    + + Y + + + ++ E 
Sbjct: 2005 YAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHD----NGVNYKIGEKWDRQGEN 2060

Query: 538  GHMLNCTCFGQGRGRWKCDPVD-QCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGE 596
            G M++CTC G G+G +KCDP +  C D   G  Y +G+ W+K   G    C C+G G   
Sbjct: 2061 GQMMSCTCLGNGKGEFKCDPHEATCYDD--GKTYHVGEQWQKEYLGAICSCTCFG-GQRG 2117

Query: 597  WHC 599
            W C
Sbjct: 2118 WRC 2120



 Score = 88.2 bits (217), Expect = 9e-17
 Identities = 45/124 (36%), Positives = 65/124 (52%), Gaps = 7/124 (5%)

Query: 2250 YAVGDEWERMSESG-FKLLCQCLGFGSGHFRCDS-SRWCHDN--GVNYKIGEKWDRQGEN 2305
            Y +GD W R  E+G + L C CLG G G + C   +  C D+  G +Y +GE W++  + 
Sbjct: 148  YKIGDTWRRPHETGGYMLECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQG 207

Query: 2306 GQMMSCTCLGNGKGEFKCDPHEATCYDDGKT-YHVGEQW-QKEYLGAICSCTCFGGQRG- 2362
              M+ CTCLG G G   C         D +T Y +G+ W +K+  G +  C C G  RG 
Sbjct: 208  WMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGE 267

Query: 2363 WRCD 2366
            W+C+
Sbjct: 268  WKCE 271



 Score = 88.2 bits (217), Expect = 9e-17
 Identities = 45/124 (36%), Positives = 65/124 (52%), Gaps = 7/124 (5%)

Query: 148  YKIGDTWRRPHETGGYMLECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQG 207
            Y +GD W R  E+G + L C CLG G G + C   +  C D+  G +Y +GE W++  + 
Sbjct: 2005 YAVGDEWERMSESG-FKLLCQCLGFGSGHFRCDS-SRWCHDN--GVNYKIGEKWDRQGEN 2060

Query: 208  WMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGE 267
              M+ CTCLG G G   C         D +T Y +G+ W +K+  G +  C C G  RG 
Sbjct: 2061 GQMMSCTCLGNGKGEFKCDPHEATCYDDGKT-YHVGEQW-QKEYLGAICSCTCFGGQRG- 2117

Query: 268  WKCE 271
            W+C+
Sbjct: 2118 WRCD 2121



 Score = 79.7 bits (195), Expect = 3e-14
 Identities = 37/84 (44%), Positives = 54/84 (64%), Gaps = 5/84 (5%)

Query: 2288 DNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEA---TCYDDGKTYHVGEQWQ 2344
            + GV Y+IG++WD+Q + G MM CTC+GNG+GE+ C  +      C  D  TY+V + + 
Sbjct: 473  NEGVMYRIGDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFH 532

Query: 2345 KEY-LGAICSCTCFGGQRG-WRCD 2366
            K +  G + +CTCFG  RG W+CD
Sbjct: 533  KRHEEGHMLNCTCFGQGRGRWKCD 556



 Score = 79.7 bits (195), Expect = 3e-14
 Identities = 37/84 (44%), Positives = 54/84 (64%), Gaps = 5/84 (5%)

Query: 473  NEGVMYRIGDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFH 532
            + GV Y+IG++WD+Q + G MM CTC+GNG+GE+ C  +      C  D  TY+V + + 
Sbjct: 2043 DNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEA---TCYDDGKTYHVGEQWQ 2099

Query: 533  KRHEEGHMLNCTCFGQGRGRWKCD 556
            K +  G + +CTCFG  RG W+CD
Sbjct: 2100 KEY-LGAICSCTCFGGQRG-WRCD 2121



 Score = 63.5 bits (153), Expect = 2e-09
 Identities = 32/82 (39%), Positives = 46/82 (56%), Gaps = 7/82 (8%)

Query: 2286 CHDNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPH---EATCYD--DGKTYHVG 2340
            C+DNG +Y+I ++W+R    G  + CTC G  +G F C+     E TC+D   G TY VG
Sbjct: 52   CYDNGKHYQINQQWERT-YLGNALVCTCYGGSRG-FNCESKPEAEETCFDKYTGNTYRVG 109

Query: 2341 EQWQKEYLGAICSCTCFGGQRG 2362
            + +++     I  CTC G  RG
Sbjct: 110  DTYERPKDSMIWDCTCIGAGRG 131



 Score = 63.5 bits (153), Expect = 2e-09
 Identities = 32/82 (39%), Positives = 46/82 (56%), Gaps = 7/82 (8%)

Query: 52   CYDNGKHYQINQQWERT-YLGNALVCTCYGGSRG-FNCESKPEAEETCFDKYTGNTYRVG 109
            C+DNG +Y+I ++W+R    G  + CTC G  +G F C+     E TC+D   G TY VG
Sbjct: 2041 CHDNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPH---EATCYD--DGKTYHVG 2095

Query: 110  DTYERPKDSMIWDCTCIGAGRG 131
            + +++     I  CTC G  RG
Sbjct: 2096 EQWQKEYLGAICSCTCFGGQRG 2117



 Score = 62.0 bits (149), Expect = 7e-09
 Identities = 37/107 (34%), Positives = 49/107 (45%), Gaps = 10/107 (9%)

Query: 2225 VGNSVNE----GLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRC 2280
            VGN   E      +Q  D    D  T   Y V D + +  E G  L C C G G G ++C
Sbjct: 499  VGNGRGEWTCIAYSQLRDQCIVDDIT---YNVNDTFHKRHEEGHMLNCTCFGQGRGRWKC 555

Query: 2281 DSSRWCHDN--GVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDP 2325
            D    C D+  G  Y+IG+ W++   +G    C C G G GE+ C P
Sbjct: 556  DPVDQCQDSETGTFYQIGDSWEKY-VHGVRYQCYCYGRGIGEWHCQP 601



 Score = 62.0 bits (149), Expect = 7e-09
 Identities = 37/107 (34%), Positives = 49/107 (45%), Gaps = 10/107 (9%)

Query: 499  VGNGRGEWTCIAYSQLRDQCIVDDIT---YNVNDTFHKRHEEGHMLNCTCFGQGRGRWKC 555
            VGN   E      +Q  D    D  T   Y V D + +  E G  L C C G G G ++C
Sbjct: 1980 VGNSVNE----GLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRC 2035

Query: 556  DPVDQCQDSETGTFYQIGDSWEKY-VHGVRYQCYCYGRGIGEWHCQP 601
            D    C D+  G  Y+IG+ W++   +G    C C G G GE+ C P
Sbjct: 2036 DSSRWCHDN--GVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDP 2080



 Score = 57.8 bits (138), Expect = 1e-07
 Identities = 24/62 (38%), Positives = 35/62 (56%), Gaps = 6/62 (9%)

Query: 2330 CYDDGKTYHVGEQWQKEYLGAICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYS 2389
            CYD+GK Y + +QW++ YLG    CTC+GG RG+ C++      +P  E T    Y   +
Sbjct: 52   CYDNGKHYQINQQWERTYLGNALVCTCYGGSRGFNCES------KPEAEETCFDKYTGNT 105

Query: 2390 QR 2391
             R
Sbjct: 106  YR 107



 Score = 57.8 bits (138), Expect = 1e-07
 Identities = 24/62 (38%), Positives = 35/62 (56%), Gaps = 6/62 (9%)

Query: 52   CYDNGKHYQINQQWERTYLGNALVCTCYGGSRGFNCES------KPEAEETCFDKYTGNT 105
            CYD+GK Y + +QW++ YLG    CTC+GG RG+ C++      +P  E T    Y   +
Sbjct: 2085 CYDDGKTYHVGEQWQKEYLGAICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYS 2144

Query: 106  YR 107
             R
Sbjct: 2145 QR 2146



 Score = 50.1 bits (118), Expect = 3e-05
 Identities = 31/110 (28%), Positives = 42/110 (38%), Gaps = 34/110 (30%)

Query: 2241 CFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDS------------------ 2282
            C D  T + Y +GD W +    G  L C C G G G ++C+                   
Sbjct: 231  CNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVR 290

Query: 2283 ---------------SRWCHDNGVNYKIGEKWDRQGENGQMMSCTCLGNG 2317
                                D+GV Y +G +W +   N QM+ CTCLGNG
Sbjct: 291  AAVYQPQPHPQPPPYGHCVTDSGVVYSVGMQWLKTQGNKQML-CTCLGNG 339



 Score = 50.1 bits (118), Expect = 3e-05
 Identities = 31/110 (28%), Positives = 42/110 (38%), Gaps = 34/110 (30%)

Query: 231  CNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVR 290
            C D  T + Y +GD W +    G  L C C G G G ++C+                   
Sbjct: 1996 CFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDS------------------ 2037

Query: 291  AAVYQPQPHPQPPPYGHCVTDSGVVYSVGMQWLKTQGNKQML-CTCLGNG 339
                                D+GV Y +G +W +   N QM+ CTCLGNG
Sbjct: 2038 ---------------SRWCHDNGVNYKIGEKWDRQGENGQMMSCTCLGNG 2072


>gi|47132547 fibronectin 1 isoform 7 preproprotein [Homo sapiens]
          Length = 657

 Score = 1440 bits (3728), Expect = 0.0
 Identities = 647/647 (100%), Positives = 647/647 (100%)

Query: 1   MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ 60
           MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ
Sbjct: 1   MLRGPGPGLLLLAVQCLGTAVPSTGASKSKRQAQQMVQPQSPVAVSQSKPGCYDNGKHYQ 60

Query: 61  INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI 120
           INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI
Sbjct: 61  INQQWERTYLGNALVCTCYGGSRGFNCESKPEAEETCFDKYTGNTYRVGDTYERPKDSMI 120

Query: 121 WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK 180
           WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK
Sbjct: 121 WDCTCIGAGRGRISCTIANRCHEGGQSYKIGDTWRRPHETGGYMLECVCLGNGKGEWTCK 180

Query: 181 PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY 240
           PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY
Sbjct: 181 PIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSY 240

Query: 241 RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP 300
           RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP
Sbjct: 241 RIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVRAAVYQPQPHP 300

Query: 301 QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC 360
           QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC
Sbjct: 301 QPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPC 360

Query: 361 VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC 420
           VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC
Sbjct: 361 VLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALC 420

Query: 421 HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI 480
           HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI
Sbjct: 421 HFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPMAAHEEICTTNEGVMYRI 480

Query: 481 GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM 540
           GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM
Sbjct: 481 GDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEEGHM 540

Query: 541 LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ 600
           LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ
Sbjct: 541 LNCTCFGQGRGRWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQ 600

Query: 601 PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRP 647
           PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRP
Sbjct: 601 PLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRP 647



 Score =  115 bits (287), Expect = 7e-25
 Identities = 57/129 (44%), Positives = 74/129 (57%), Gaps = 5/129 (3%)

Query: 2238 DDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHDNGVNYKIGE 2297
            +++CFD YT + Y VGD +ER  +S     C C+G G G   C  +  CH+ G +YKIG+
Sbjct: 94   EETCFDKYTGNTYRVGDTYERPKDSMI-WDCTCIGAGRGRISCTIANRCHEGGQSYKIGD 152

Query: 2298 KWDRQGE-NGQMMSCTCLGNGKGEFKCDPHEATCYDD--GKTYHVGEQWQKEYLG-AICS 2353
             W R  E  G M+ C CLGNGKGE+ C P    C+D   G +Y VGE W+K Y G  +  
Sbjct: 153  TWRRPHETGGYMLECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQGWMMVD 212

Query: 2354 CTCFGGQRG 2362
            CTC G   G
Sbjct: 213  CTCLGEGSG 221



 Score = 98.6 bits (244), Expect = 7e-20
 Identities = 54/172 (31%), Positives = 73/172 (42%), Gaps = 34/172 (19%)

Query: 2221 EVVTVGNSVNEGLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRC 2280
            E V +GN   E   +P  + CFD    + Y VG+ WE+  +    + C CLG GSG   C
Sbjct: 166  ECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQGWMMVDCTCLGEGSGRITC 225

Query: 2281 DSSRWCHDNG--VNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPH------------ 2326
             S   C+D     +Y+IG+ W ++   G ++ C C GNG+GE+KC+ H            
Sbjct: 226  TSRNRCNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGP 285

Query: 2327 ----EATCY----------------DDGKTYHVGEQWQKEYLGAICSCTCFG 2358
                 A  Y                D G  Y VG QW K        CTC G
Sbjct: 286  FTDVRAAVYQPQPHPQPPPYGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLG 337



 Score = 90.9 bits (224), Expect = 1e-17
 Identities = 40/123 (32%), Positives = 65/123 (52%), Gaps = 8/123 (6%)

Query: 2250 YAVGDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHD----NGVNYKIGEKWDRQGEN 2305
            Y +GD+W++  + G  + C C+G G G + C +     D    + + Y + + + ++ E 
Sbjct: 478  YRIGDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFHKRHEE 537

Query: 2306 GQMMSCTCLGNGKGEFKCDPHEATCYDD--GKTYHVGEQWQKEYLGAICSCTCFG-GQRG 2362
            G M++CTC G G+G +KCDP +  C D   G  Y +G+ W+K   G    C C+G G   
Sbjct: 538  GHMLNCTCFGQGRGRWKCDPVD-QCQDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGE 596

Query: 2363 WRC 2365
            W C
Sbjct: 597  WHC 599



 Score = 88.2 bits (217), Expect = 9e-17
 Identities = 45/124 (36%), Positives = 65/124 (52%), Gaps = 7/124 (5%)

Query: 2250 YAVGDEWERMSESG-FKLLCQCLGFGSGHFRCDS-SRWCHDN--GVNYKIGEKWDRQGEN 2305
            Y +GD W R  E+G + L C CLG G G + C   +  C D+  G +Y +GE W++  + 
Sbjct: 148  YKIGDTWRRPHETGGYMLECVCLGNGKGEWTCKPIAEKCFDHAAGTSYVVGETWEKPYQG 207

Query: 2306 GQMMSCTCLGNGKGEFKCDPHEATCYDDGKT-YHVGEQW-QKEYLGAICSCTCFGGQRG- 2362
              M+ CTCLG G G   C         D +T Y +G+ W +K+  G +  C C G  RG 
Sbjct: 208  WMMVDCTCLGEGSGRITCTSRNRCNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGE 267

Query: 2363 WRCD 2366
            W+C+
Sbjct: 268  WKCE 271



 Score = 79.7 bits (195), Expect = 3e-14
 Identities = 37/84 (44%), Positives = 54/84 (64%), Gaps = 5/84 (5%)

Query: 2288 DNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPHEA---TCYDDGKTYHVGEQWQ 2344
            + GV Y+IG++WD+Q + G MM CTC+GNG+GE+ C  +      C  D  TY+V + + 
Sbjct: 473  NEGVMYRIGDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRDQCIVDDITYNVNDTFH 532

Query: 2345 KEY-LGAICSCTCFGGQRG-WRCD 2366
            K +  G + +CTCFG  RG W+CD
Sbjct: 533  KRHEEGHMLNCTCFGQGRGRWKCD 556



 Score = 63.5 bits (153), Expect = 2e-09
 Identities = 32/82 (39%), Positives = 46/82 (56%), Gaps = 7/82 (8%)

Query: 2286 CHDNGVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDPH---EATCYD--DGKTYHVG 2340
            C+DNG +Y+I ++W+R    G  + CTC G  +G F C+     E TC+D   G TY VG
Sbjct: 52   CYDNGKHYQINQQWERT-YLGNALVCTCYGGSRG-FNCESKPEAEETCFDKYTGNTYRVG 109

Query: 2341 EQWQKEYLGAICSCTCFGGQRG 2362
            + +++     I  CTC G  RG
Sbjct: 110  DTYERPKDSMIWDCTCIGAGRG 131



 Score = 62.0 bits (149), Expect = 7e-09
 Identities = 37/107 (34%), Positives = 49/107 (45%), Gaps = 10/107 (9%)

Query: 2225 VGNSVNE----GLNQPTDDSCFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRC 2280
            VGN   E      +Q  D    D  T   Y V D + +  E G  L C C G G G ++C
Sbjct: 499  VGNGRGEWTCIAYSQLRDQCIVDDIT---YNVNDTFHKRHEEGHMLNCTCFGQGRGRWKC 555

Query: 2281 DSSRWCHDN--GVNYKIGEKWDRQGENGQMMSCTCLGNGKGEFKCDP 2325
            D    C D+  G  Y+IG+ W++   +G    C C G G GE+ C P
Sbjct: 556  DPVDQCQDSETGTFYQIGDSWEKY-VHGVRYQCYCYGRGIGEWHCQP 601



 Score = 57.8 bits (138), Expect = 1e-07
 Identities = 24/62 (38%), Positives = 35/62 (56%), Gaps = 6/62 (9%)

Query: 2330 CYDDGKTYHVGEQWQKEYLGAICSCTCFGGQRGWRCDNCRRPGGEPSPEGTTGQSYNQYS 2389
            CYD+GK Y + +QW++ YLG    CTC+GG RG+ C++      +P  E T    Y   +
Sbjct: 52   CYDNGKHYQINQQWERTYLGNALVCTCYGGSRGFNCES------KPEAEETCFDKYTGNT 105

Query: 2390 QR 2391
             R
Sbjct: 106  YR 107



 Score = 50.1 bits (118), Expect = 3e-05
 Identities = 31/110 (28%), Positives = 42/110 (38%), Gaps = 34/110 (30%)

Query: 2241 CFDPYTVSHYAVGDEWERMSESGFKLLCQCLGFGSGHFRCDS------------------ 2282
            C D  T + Y +GD W +    G  L C C G G G ++C+                   
Sbjct: 231  CNDQDTRTSYRIGDTWSKKDNRGNLLQCICTGNGRGEWKCERHTSVQTTSSGSGPFTDVR 290

Query: 2283 ---------------SRWCHDNGVNYKIGEKWDRQGENGQMMSCTCLGNG 2317
                                D+GV Y +G +W +   N QM+ CTCLGNG
Sbjct: 291  AAVYQPQPHPQPPPYGHCVTDSGVVYSVGMQWLKTQGNKQML-CTCLGNG 339


>gi|93141047 collagen, type XII, alpha 1 long isoform precursor [Homo
            sapiens]
          Length = 3063

 Score =  387 bits (995), Expect = e-107
 Identities = 380/1540 (24%), Positives = 643/1540 (41%), Gaps = 145/1540 (9%)

Query: 628  IQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQY 687
            + W+   P  + +Y++ + P    G  +E T+ G   +  ++GLK G             
Sbjct: 832  LSWSGA-PGKVKQYLVTYTPVAG-GETQEVTVRGDTTNTVLQGLKEG------------- 876

Query: 688  GHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVT-EITASSFVVSWVSASDT 746
                 T++  + T+       + + GE T      +  + VT +IT +S    W SA   
Sbjct: 877  -----TQYALSVTALYASGAGDALFGEGTTLEERGSPQDLVTKDITDTSIGAYWTSAPGM 931

Query: 747  VSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTS 806
            V G+RV ++   +  +    +LP  A    I +L P  KY ++V+     GE   +   +
Sbjct: 932  VRGYRVSWKSLYDDVDTGEKNLPEDAIHTMIENLQPETKYRISVFATYSSGEGEPLTGDA 991

Query: 807  QTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVT 866
             T          VD+  + ++ V W      +  YR+VY P   G      +P T  S  
Sbjct: 992  TTELSQDSKTLKVDEETENTMRVTWKPAPGKVVNYRVVYRPHGRGKQMVAKVPPTVTSTV 1051

Query: 867  LSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIM 926
            L  LQP   Y+IT+  + +  E       ++ +GT  S    SPR+L+  + T     + 
Sbjct: 1052 LKRLQPQTTYDITVLPIYKMGEGK----LRQGSGTTAS-RFKSPRNLKTSDPTMSSFRVT 1106

Query: 927  WTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRES 986
            W P    V GY+V   P       G+ +    +    +  L  G TY   VF +  G ES
Sbjct: 1107 WEPAPGEVKGYKVTFHPTGDDRRLGELVVGPYDNTVVLEELRAGTTYKVNVFGMFDGGES 1166

Query: 987  KPLTAQQTTKLDAPTNLQFVN---------ETDSTVLV--RWTPPRAQITGYRLTVGLTR 1035
             PL  Q+ T L   T +  ++         E D  +LV   W+  RA     R  +    
Sbjct: 1167 SPLVGQEMTTLSDTTVMPILSSGMECLTRAEADIVLLVDGSWSIGRANFRTVRSFISRI- 1225

Query: 1036 RGQPRQYNVGPSVSKYPLRNLQ--PASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPP 1093
                  +++GP   +  L      P +E+ ++    K +            LQ  +++P 
Sbjct: 1226 ---VEVFDIGPKRVQIALAQYSGDPRTEWQLNAHRDKKS-----------LLQAVANLP- 1270

Query: 1094 YNTEVTETTIVITWTPAPRIGFKLGVRP--------------SQGGEAPREVTSDSG--- 1136
            Y    T T + + +        + G+RP                  EAP +   D G   
Sbjct: 1271 YKGGNTLTGMALNFIRQQNFRTQAGMRPRARKIGVLITDGKSQDDVEAPSKKLKDEGVEL 1330

Query: 1137 -----------SIVVSGLTPGVEYVYTI----QVLRDGQERDAPIVNKVVTP--LSPPTN 1179
                        + +    P   + Y +     + R   +    + N V  P  L  P+N
Sbjct: 1331 FAIGIKNADEVELKMIATDPDDTHAYNVADFESLSRIVDDLTINLCNSVKGPGDLEAPSN 1390

Query: 1180 LHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSP 1239
            L +          VSW    +  +  Y++   P +G  G   E  V   ++S    +L P
Sbjct: 1391 LVISERTHRS-FRVSWT-PPSDSVDRYKVEYYPVSG--GKRQEFYVSRMETSTVLKDLKP 1446

Query: 1240 GLEYNVSVYTVKDDKESVPISDTIIPEVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGYR 1299
              EY V+VY+V +D+ S P+  T       +  L+  D+  +++ ++W P+  +T  GY 
Sbjct: 1447 ETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVVSLNIYDVGPTTMHVQWQPVGGAT--GYI 1504

Query: 1300 ITVVAAGEGIPIF--EDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTA 1357
            ++     +  P    E  +  +V    +T L P  +Y ++V  +++   S P T+ + T 
Sbjct: 1505 LSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEPVTVREVTL 1564

Query: 1358 -VPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVL 1416
             +P P DL+  ++   TM V W P P   +  ++VRY     EEDV E+ +  S+ +  L
Sbjct: 1565 PLPRPQDLKLRDVTHSTMNVFWEPVPG-KVRKYIVRYKTP--EEDVKEVEVDRSETSTSL 1621

Query: 1417 TNLLPGTEYVVSVSSVYEQHESTPLRGRQKTG-LDSPTGIDFSDITANSFTVHWIAPRAT 1475
             +L   T Y VSVS+V+++ ES P+  ++ T  + +PT +  +++T+  F   W    + 
Sbjct: 1622 KDLFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPAPTNLKITEVTSEGFRGTWDHGASD 1681

Query: 1476 ITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGRE-ESPLLIGQ 1534
            ++ YRI   P   S +  E  +    N++   NL P T Y VSI A+   E ES  LIG 
Sbjct: 1682 VSLYRITWAPFGSSDK-METILNGDENTLVFENLNPNTIYEVSITAIYPDESESDDLIGS 1740

Query: 1535 QSTVSDV--------PRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFT 1586
            + T+  +        PR+L+V  AT  SL + WD  +  V+ YRITY  + G    Q  T
Sbjct: 1741 ERTLPILTTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQTTT 1800

Query: 1587 VPGSKSTATISGLKPGVDYTITVYAVT-----GRGDSPASSKPISINYRTEIDKPSQMQV 1641
            + G +++  +  LKP   YTITV ++      GR      +KP++            ++V
Sbjct: 1801 IGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNT--------VRNLRV 1852

Query: 1642 TDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEY-- 1699
             D   ++++V+W  +      Y++   P  G GP +      +     +  LQP   Y  
Sbjct: 1853 YDPSTSTLNVRWDHAEGNPRQYKLFYAPAAG-GPEELVPIPGNTNYAILRNLQPDTSYTV 1911

Query: 1700 -VVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYS 1758
             VV VY +   G +    +T +  + R   +   +   +S+ + W+   G V +YRV YS
Sbjct: 1912 TVVPVYTEGDGGRTSDTGRTLMRGLAR--NVQVYNPTPNSLDVRWDPAPGPVLQYRVVYS 1969

Query: 1759 SPEDGIH--ELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIP-- 1814
             P DG    E    P G      L+ L P + Y+V++VAL+ D E  P    Q   +P  
Sbjct: 1970 -PVDGTRPSESIVVP-GNTRMVHLERLIPDTLYSVNLVALYSDGEGNPS-PAQGRTLPRS 2026

Query: 1815 APTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDS-SSVVVSGL 1873
             P +L+    T  SLS  W   +  +  YR+  +P     P+ E    P   ++V++  L
Sbjct: 2027 GPRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGD-PIDEYTTVPGRRNNVILQPL 2085

Query: 1874 MVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETIT 1933
               T Y+++V A+ +        G   T+  + PP+   ++D   T   +SW      + 
Sbjct: 2086 QPDTPYKITVIAVYEDGDGGHLTGNGRTV-GLLPPQNIHISDEWYTRFRVSWDPSPSPVL 2144

Query: 1934 GFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTA 1993
            G+++   P     P++  +  ++ SYT+  L P T Y + +Y   D+  S P+    +T 
Sbjct: 2145 GYKIVYKPVGSNEPMEAFVG-EMTSYTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQGTTL 2203

Query: 1994 IDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITG 2053
                ++L+      ++  V W P RA  T Y +K   P    R      R   T    TG
Sbjct: 2204 YLNVTDLKTYQIGWDTFCVKWSPHRA-ATSYRLKL-SPADGTRGQEITVRGSETSHCFTG 2261

Query: 2054 LEPGTEYTIYVIALKNNQKSEPL-IGRKKTVQKTPFVTHP 2092
            L P T+Y + V     N +   + +    TV+ T   T P
Sbjct: 2262 LSPDTDYGVTVFVQTPNLEGPGVSVKEHTTVKPTEAPTEP 2301



 Score =  297 bits (760), Expect = 1e-79
 Identities = 307/1324 (23%), Positives = 527/1324 (39%), Gaps = 86/1324 (6%)

Query: 798  EQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELN 857
            EQ L     +   P  P D +  +V        WS     +  Y I Y  +       + 
Sbjct: 621  EQELAAIKKKAYVP--PKDLSFSEVTSYGFKTNWSPAGENVFSYHITYKEAAGDDEVTVV 678

Query: 858  LPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVE 917
             P ++ SV LS L+P   Y + + A  E+  S P+  ++ T      +   +PR+L+  +
Sbjct: 679  EPASSTSVVLSSLKPETLYLVNVTAEYEDGFSIPLAGEETT-----EEVKGAPRNLKVTD 733

Query: 918  VTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKV 977
             T     I WT     V  YR+   PV   GE  +           +  L P   Y   V
Sbjct: 734  ETTDSFKITWTQAPGRVLRYRIIYRPV-AGGESREVTTPPNQRRRTLENLIPDTKYEVSV 792

Query: 978  FAVSHGRESKPLTAQQTTK--LDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTR 1035
                      PLT    T+     P +L+  + T ST+ + W+    ++  Y +T     
Sbjct: 793  IPEYFSGPGTPLTGNAATEEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTYTPVA 852

Query: 1036 RGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQP-GSSIPPY 1094
             G+ ++  V    +   L+ L+  ++Y +S+ A+  +       G  TTL+  GS     
Sbjct: 853  GGETQEVTVRGDTTNTVLQGLKEGTQYALSVTALYASGAGDALFGEGTTLEERGSPQDLV 912

Query: 1095 NTEVTETTIVITWTPAP------RIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVE 1148
              ++T+T+I   WT AP      R+ +K        GE  + +  D+   ++  L P  +
Sbjct: 913  TKDITDTSIGAYWTSAPGMVRGYRVSWKSLYDDVDTGE--KNLPEDAIHTMIENLQPETK 970

Query: 1149 YVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRI 1208
            Y  ++       E + P+     T LS  +            + V+W +     +  YR+
Sbjct: 971  YRISVFATYSSGEGE-PLTGDATTELSQDSKTLKVDEETENTMRVTW-KPAPGKVVNYRV 1028

Query: 1209 TTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESV--PISDTIIPE 1266
               P    +G  +   V    +S     L P   Y+++V  +    E      S T    
Sbjct: 1029 VYRPHG--RGKQMVAKVPPTVTSTVLKRLQPQTTYDITVLPIYKMGEGKLRQGSGTTASR 1086

Query: 1267 VPQLTDLSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIFEDFVDSSVGYYTVT 1326
                 +L   D T SS  + W P     + GY++T    G+   + E  V        + 
Sbjct: 1087 FKSPRNLKTSDPTMSSFRVTWEPA-PGEVKGYKVTFHPTGDDRRLGELVVGPYDNTVVLE 1145

Query: 1327 GLEPGIDYDISVITLINGGESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAP------ 1380
             L  G  Y ++V  + +GGES+P    + T +   T +   + G + +    A       
Sbjct: 1146 ELRAGTTYKVNVFGMFDGGESSPLVGQEMTTLSDTTVMPILSSGMECLTRAEADIVLLVD 1205

Query: 1381 -PPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSV----SSVYEQ 1435
               SI   NF    S +    +V ++       A+   +  P TE+ ++      S+ + 
Sbjct: 1206 GSWSIGRANFRTVRSFISRIVEVFDIGPKRVQIALAQYSGDPRTEWQLNAHRDKKSLLQA 1265

Query: 1436 HESTPLRGRQKTGLDSPTGIDFSDITANSF-TVHWIAPRATITGYRIRHHPEHFSGRPRE 1494
              + P +G      ++ TG+  + I   +F T   + PRA   G  I             
Sbjct: 1266 VANLPYKGG-----NTLTGMALNFIRQQNFRTQAGMRPRARKIGVLITDGKSQDDVEAPS 1320

Query: 1495 DRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVS--------------- 1539
             ++      +    +    E  + ++A +  +     +    ++S               
Sbjct: 1321 KKLKDEGVELFAIGIKNADEVELKMIATDPDDTHAYNVADFESLSRIVDDLTINLCNSVK 1380

Query: 1540 -----DVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTA 1594
                 + P +L +   T  S  +SW  P+ +V  Y++ Y    G    QEF V   +++ 
Sbjct: 1381 GPGDLEAPSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSGGKR-QEFYVSRMETST 1439

Query: 1595 TISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWL 1654
             +  LKP  +Y + VY+V         S+P+    +T       + + DV   ++ V+W 
Sbjct: 1440 VLKDLKPETEYVVNVYSVV----EDEYSEPLKGTEKTLPVPVVSLNIYDVGPTTMHVQWQ 1495

Query: 1655 PSSSPVTGYRVTTTPKNGPGPTKTKTA--GPDQTEMTIEGLQPTVEYVVSVYAQNPSGES 1712
            P     TGY ++  P     PT+ K    GP   +M +  L P  EY V+V A      S
Sbjct: 1496 PVGG-ATGYILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTS 1554

Query: 1713 QPLVQTAVT-NIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAP 1771
            +P+    VT  + RP+ L   DV   ++ + WE   G+V +Y V Y +PE+ + E+    
Sbjct: 1555 EPVTVREVTLPLPRPQDLKLRDVTHSTMNVFWEPVPGKVRKYIVRYKTPEEDVKEV--EV 1612

Query: 1772 DGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQST-AIPAPTDLKFTQVTPTSLS 1830
            D  E +  L+ L   + YTVSV A+HD+ ES P+   ++T  +PAPT+LK T+VT     
Sbjct: 1613 DRSETSTSLKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPAPTNLKITEVTSEGFR 1672

Query: 1831 AQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYAL---- 1886
              W      ++ YR+   P   +  M+ I L  D +++V   L   T YEVS+ A+    
Sbjct: 1673 GTWDHGASDVSLYRITWAPFGSSDKMETI-LNGDENTLVFENLNPNTIYEVSITAIYPDE 1731

Query: 1887 ---KDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPAN 1943
                D + S     ++TT    S PR  +V +AT  ++T+ W   +  +  +++   P+ 
Sbjct: 1732 SESDDLIGSERTLPILTTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPST 1791

Query: 1944 GQTPIQ-RTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDAST-AIDAPSNLR 2001
            G+   Q  TI     S  +  L+P T Y I + +L  +     +     T  ++   NLR
Sbjct: 1792 GEGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLR 1851

Query: 2002 FLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYT 2061
                + ++L V W         Y + Y      P E+VP P      A +  L+P T YT
Sbjct: 1852 VYDPSTSTLNVRWDHAEGNPRQYKLFYAPAAGGPEELVPIP-GNTNYAILRNLQPDTSYT 1910

Query: 2062 IYVI 2065
            + V+
Sbjct: 1911 VTVV 1914



 Score =  201 bits (510), Expect = 9e-51
 Identities = 157/551 (28%), Positives = 237/551 (43%), Gaps = 20/551 (3%)

Query: 1542 PRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKP 1601
            P+DL     T      +W      V  Y ITY E  G+  V     P S ++  +S LKP
Sbjct: 635  PKDLSFSEVTSYGFKTNWSPAGENVFSYHITYKEAAGDDEVT-VVEPASSTSVVLSSLKP 693

Query: 1602 GVDYTITVYAVTGRGDSPASSKPISINYRTEIDK--PSQMQVTDVQDNSISVKWLPSSSP 1659
               Y + V A    G     S P++    TE  K  P  ++VTD   +S  + W  +   
Sbjct: 694  ETLYLVNVTAEYEDG----FSIPLAGEETTEEVKGAPRNLKVTDETTDSFKITWTQAPGR 749

Query: 1660 VTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTA 1719
            V  YR+   P  G G ++  T  P+Q   T+E L P  +Y VSV  +  SG   PL   A
Sbjct: 750  VLRYRIIYRPVAG-GESREVTTPPNQRRRTLENLIPDTKYEVSVIPEYFSGPGTPLTGNA 808

Query: 1720 VTNIDR--PKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDT 1777
             T   R  P+ L  +D    ++K++W    G+V +Y VTY+ P  G         G+   
Sbjct: 809  ATEEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTYT-PVAGGETQEVTVRGDTTN 867

Query: 1778 AELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIP--APTDLKFTQVTPTSLSAQWTP 1835
              LQGL+ G++Y +SV AL+       L G  +T     +P DL    +T TS+ A WT 
Sbjct: 868  TVLQGLKEGTQYALSVTALYASGAGDALFGEGTTLEERGSPQDLVTKDITDTSIGAYWTS 927

Query: 1836 PNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPA 1895
                + GYRV            E NL  D+   ++  L   TKY +SV+A   +    P 
Sbjct: 928  APGMVRGYRVSWKSLYDDVDTGEKNLPEDAIHTMIENLQPETKYRISVFATYSSGEGEPL 987

Query: 1896 QGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPD 1955
             G  TT E     +  +V + TE T+ ++W+     +  ++V   P      +   + P 
Sbjct: 988  TGDATT-ELSQDSKTLKVDEETENTMRVTWKPAPGKVVNYRVVYRPHGRGKQMVAKVPPT 1046

Query: 1956 VRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTA--IDAPSNLRFLATTPNSLLVS 2013
            V S  +  LQP T Y I +  +             +TA    +P NL+    T +S  V+
Sbjct: 1047 VTSTVLKRLQPQTTYDITVLPIYKMGEGKLRQGSGTTASRFKSPRNLKTSDPTMSSFRVT 1106

Query: 2014 WQPPRARITGYIIKYEKPGSPPR--EVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQ 2071
            W+P    + GY + +   G   R  E+V  P        +  L  GT Y + V  + +  
Sbjct: 1107 WEPAPGEVKGYKVTFHPTGDDRRLGELVVGPYDNT--VVLEELRAGTTYKVNVFGMFDGG 1164

Query: 2072 KSEPLIGRKKT 2082
            +S PL+G++ T
Sbjct: 1165 ESSPLVGQEMT 1175



 Score =  201 bits (510), Expect = 9e-51
 Identities = 214/835 (25%), Positives = 345/835 (41%), Gaps = 77/835 (9%)

Query: 623  PNSHPIQWNAPQP-SHISKYILRWRPKNSVG--RWKEATIPGHLNSYTIKGLKPGVVYEG 679
            P +  +QW   QP    + YIL ++P       R KE  +   +N   +  L P   Y  
Sbjct: 1487 PTTMHVQW---QPVGGATGYILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYA- 1542

Query: 680  QLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSE-SVTEITASSFVV 738
              +++Q   H            TS PVT   VT       PL    +  + ++T S+  V
Sbjct: 1543 --VTVQAVLHD----------LTSEPVTVREVT------LPLPRPQDLKLRDVTHSTMNV 1584

Query: 739  SWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGE 798
             W      V  + V Y+  EE  +   +D   T+TS+   DL     Y V+V  + ++GE
Sbjct: 1585 FWEPVPGKVRKYIVRYKTPEEDVKEVEVDRSETSTSLK--DLFSQTLYTVSVSAVHDEGE 1642

Query: 799  QSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNL 858
               + +   T    AP +  + +V        W    + ++ YRI ++P       E  L
Sbjct: 1643 SPPVTAQETTRPVPAPTNLKITEVTSEGFRGTWDHGASDVSLYRITWAPFGSSDKMETIL 1702

Query: 859  PETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQE------TTGTPRSDTVPSPRD 912
                N++   +L P   Y ++I A+  ++  +  +I  E      TT  P+S     PR+
Sbjct: 1703 NGDENTLVFENLNPNTIYEVSITAIYPDESESDDLIGSERTLPILTTQAPKS----GPRN 1758

Query: 913  LQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVT 972
            LQ    T   +T+ W P    V  YR+   P    G         R     +  L P   
Sbjct: 1759 LQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQTTTIGGRQNSVVLQKLKPDTP 1818

Query: 973  YYFKVFAVSHGRESKPLTAQQTTK-LDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTV 1031
            Y   V ++    E   +T +  TK L+   NL+  + + ST+ VRW         Y+L  
Sbjct: 1819 YTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRVYDPSTSTLNVRWDHAEGNPRQYKLFY 1878

Query: 1032 GLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPG--S 1089
                 G      +  + +   LRNLQP + YTV++V +    +  + +    TL  G   
Sbjct: 1879 APAAGGPEELVPIPGNTNYAILRNLQPDTSYTVTVVPVYTEGDGGRTSDTGRTLMRGLAR 1938

Query: 1090 SIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSG------- 1142
            ++  YN   T  ++ + W PAP    +  V  S     P + T  S SIVV G       
Sbjct: 1939 NVQVYNP--TPNSLDVRWDPAPGPVLQYRVVYS-----PVDGTRPSESIVVPGNTRMVHL 1991

Query: 1143 --LTPGVEY-VYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERST 1199
              L P   Y V  + +  DG+   +P   + + P S P NL +     T  L+V+W+ + 
Sbjct: 1992 ERLIPDTLYSVNLVALYSDGEGNPSPAQGRTL-PRSGPRNLRV-FGETTNSLSVAWDHAD 2049

Query: 1200 TPDITGYRITTTPTNGQQGNSLEE--VVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESV 1257
             P +  YRI  +PT    G+ ++E   V   +++     L P   Y ++V  V +D +  
Sbjct: 2050 GP-VQQYRIIYSPT---VGDPIDEYTTVPGRRNNVILQPLQPDTPYKITVIAVYEDGDGG 2105

Query: 1258 PISD---TIIPEVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIFED 1314
             ++    T+    PQ   +S  D   +   + W P + S ++GY+I     G   P+ E 
Sbjct: 2106 HLTGNGRTVGLLPPQNIHIS--DEWYTRFRVSWDP-SPSPVLGYKIVYKPVGSNEPM-EA 2161

Query: 1315 FVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAVPPPTDLRFTNIGPDTM 1374
            FV      YT+  L P   YD++V    + G S P T    T     TDL+   IG DT 
Sbjct: 2162 FVGEMTS-YTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQGTTLYLNVTDLKTYQIGWDTF 2220

Query: 1375 RVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSV 1429
             V W+P  +   T++ ++ SP        E+++  S+ +   T L P T+Y V+V
Sbjct: 2221 CVKWSPHRA--ATSYRLKLSPADGTRG-QEITVRGSETSHCFTGLSPDTDYGVTV 2272



 Score =  193 bits (490), Expect = 2e-48
 Identities = 214/887 (24%), Positives = 369/887 (41%), Gaps = 87/887 (9%)

Query: 1174 LSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTP-TNGQQGNSLEEVVHADQSSC 1232
            + PP+NL +     +  + ++W  S +P +TGY++  TP T G + ++L   V    ++ 
Sbjct: 334  VEPPSNL-IAMEVSSKYVKLNWNPSPSP-VTGYKVILTPMTAGSRQHALS--VGPQTTTL 389

Query: 1233 TFDNLSPGLEYNVSVYTVKD--DKESVPISDTIIPEVPQLTDLSFVDITDSSIGL--RWT 1288
            +  +LS   EY +SV  +K     E + I +   P   Q+     VDI    + L     
Sbjct: 390  SVRDLSADTEYQISVSAMKGMTSSEPISIMEKTQPMKVQVECSRGVDIKADIVFLVDGSY 449

Query: 1289 PLNSSTIIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLIN----- 1343
             +  +  +  R  +    +   I  + V  S+  Y+    +P  ++ +   T +      
Sbjct: 450  SIGIANFVKVRAFLEVLVKSFEISPNRVQISLVQYS---RDPHTEFTLKKFTKVEDIIEA 506

Query: 1344 -------GGES----APTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAPP------PSIDL 1386
                   GG +    A T + ++  VP       +N+    + +T          P+I L
Sbjct: 507  INTFPYRGGSTNTGKAMTYVREKIFVPSKGSR--SNVPKVMILITDGKSSDAFRDPAIKL 564

Query: 1387 TNFLVRYSPVKNEEDV-AELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQ 1445
             N  V    V  ++ V +EL    S  A   T++    ++       +E  +S  LR  Q
Sbjct: 565  RNSDVEIFAVGVKDAVRSELEAIASPPAE--THVFTVEDFDAFQRISFELTQSICLRIEQ 622

Query: 1446 ------KTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRV-P 1498
                  K     P  + FS++T+  F  +W      +  Y I +  +  +G      V P
Sbjct: 623  ELAAIKKKAYVPPKDLSFSEVTSYGFKTNWSPAGENVFSYHITY--KEAAGDDEVTVVEP 680

Query: 1499 HSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQST--VSDVPRDLEVVAATPTSLL 1556
             S  S+ L++L P T Y+V++ A      S  L G+++T  V   PR+L+V   T  S  
Sbjct: 681  ASSTSVVLSSLKPETLYLVNVTAEYEDGFSIPLAGEETTEEVKGAPRNLKVTDETTDSFK 740

Query: 1557 ISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRG 1616
            I+W      V  YRI Y    G    +E T P ++   T+  L P   Y ++V      G
Sbjct: 741  ITWTQAPGRVLRYRIIYRPVAGGES-REVTTPPNQRRRTLENLIPDTKYEVSVIPEYFSG 799

Query: 1617 DSPASSKPISINYRTEIDK--PSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPG 1674
                   P++ N  TE  +  P  ++V+D   +++ + W  +   V  Y VT TP  G G
Sbjct: 800  PGT----PLTGNAATEEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTYTPVAG-G 854

Query: 1675 PTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDR--PKGLAFT 1732
             T+  T   D T   ++GL+   +Y +SV A   SG    L     T  +R  P+ L   
Sbjct: 855  ETQEVTVRGDTTNTVLQGLKEGTQYALSVTALYASGAGDALFGEGTTLEERGSPQDLVTK 914

Query: 1733 DVDVDSIKIAWESPQGQVSRYRVTYSS------------PEDGIHELFPAPDGEEDTAEL 1780
            D+   SI   W S  G V  YRV++ S            PED IH +            +
Sbjct: 915  DITDTSIGAYWTSAPGMVRGYRVSWKSLYDDVDTGEKNLPEDAIHTM------------I 962

Query: 1781 QGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTD-LKFTQVTPTSLSAQWTPPNVQ 1839
            + L+P ++Y +SV A +   E +PL G  +T +   +  LK  + T  ++   W P   +
Sbjct: 963  ENLQPETKYRISVFATYSSGEGEPLTGDATTELSQDSKTLKVDEETENTMRVTWKPAPGK 1022

Query: 1840 LTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVV 1899
            +  YRV   P  + G      + P  +S V+  L   T Y+++V  +      +  QG  
Sbjct: 1023 VVNYRVVYRPHGR-GKQMVAKVPPTVTSTVLKRLQPQTTYDITVLPIYKMGEGKLRQGSG 1081

Query: 1900 TTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPI-QRTIKPDVRS 1958
            TT      PR  + +D T ++  ++W      + G++V   P      + +  + P   +
Sbjct: 1082 TTASRFKSPRNLKTSDPTMSSFRVTWEPAPGEVKGYKVTFHPTGDDRRLGELVVGPYDNT 1141

Query: 1959 YTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLAT 2005
              +  L+ GT YK+ ++ + D   SSP+V    T +   + +  L++
Sbjct: 1142 VVLEELRAGTTYKVNVFGMFDGGESSPLVGQEMTTLSDTTVMPILSS 1188



 Score =  176 bits (447), Expect = 2e-43
 Identities = 214/960 (22%), Positives = 374/960 (38%), Gaps = 130/960 (13%)

Query: 1323 YTVTGLEPGIDYDISVITLINGG--ESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAP 1380
            + V   +  +D    +I+ +  G  E     ++ +  V PP++L    +    +++ W P
Sbjct: 297  FNVANFDAIVDIQNEIISQVCSGVDEQLGELVSGEEVVEPPSNLIAMEVSSKYVKLNWNP 356

Query: 1381 PPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTP 1440
             PS  +T + V  +P+        LS+ P    + + +L   TEY +SVS++     S P
Sbjct: 357  SPS-PVTGYKVILTPMTAGSRQHALSVGPQTTTLSVRDLSADTEYQISVSAMKGMTSSEP 415

Query: 1441 LRGRQKT-----------GLDSPTGIDFSDITANSFTV---HWIAPRA----TITGYRIR 1482
            +   +KT           G+D    I F  +   S+++   +++  RA     +  + I 
Sbjct: 416  ISIMEKTQPMKVQVECSRGVDIKADIVF--LVDGSYSIGIANFVKVRAFLEVLVKSFEIS 473

Query: 1483 HHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREES------------PL 1530
             +    S   +  R PH+    TL   T   + + +I     R  S             +
Sbjct: 474  PNRVQIS-LVQYSRDPHT--EFTLKKFTKVEDIIEAINTFPYRGGSTNTGKAMTYVREKI 530

Query: 1531 LIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTV--- 1587
             +  + + S+VP+ + ++    +S   ++  PA+ +R           NS V+ F V   
Sbjct: 531  FVPSKGSRSNVPKVMILITDGKSS--DAFRDPAIKLR-----------NSDVEIFAVGVK 577

Query: 1588 PGSKSTATISGLKPGVDYTITVYAVTG-RGDSPASSKPISINYRTEID--------KPSQ 1638
               +S        P   +  TV      +  S   ++ I +    E+          P  
Sbjct: 578  DAVRSELEAIASPPAETHVFTVEDFDAFQRISFELTQSICLRIEQELAAIKKKAYVPPKD 637

Query: 1639 MQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGP-DQTEMTIEGLQPTV 1697
            +  ++V        W P+   V  Y +T   K   G  +     P   T + +  L+P  
Sbjct: 638  LSFSEVTSYGFKTNWSPAGENVFSYHITY--KEAAGDDEVTVVEPASSTSVVLSSLKPET 695

Query: 1698 EYVVSVYAQNPSGESQPLVQTAVTNIDR--PKGLAFTDVDVDSIKIAWESPQGQVSRYRV 1755
             Y+V+V A+   G S PL     T   +  P+ L  TD   DS KI W    G+V RYR+
Sbjct: 696  LYLVNVTAEYEDGFSIPLAGEETTEEVKGAPRNLKVTDETTDSFKITWTQAPGRVLRYRI 755

Query: 1756 TYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQST--AI 1813
             Y     G       P  +     L+ L P ++Y VSV+  +      PL G  +T    
Sbjct: 756  IYRPVAGGESREVTTPPNQR-RRTLENLIPDTKYEVSVIPEYFSGPGTPLTGNAATEEVR 814

Query: 1814 PAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGL 1873
              P DL+ +  T +++   W+    ++  Y V  TP    G  +E+ +  D+++ V+ GL
Sbjct: 815  GNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTYTP-VAGGETQEVTVRGDTTNTVLQGL 873

Query: 1874 MVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETIT 1933
               T+Y +SV AL  +       G  TTLE    P+     D T+T+I   W +    + 
Sbjct: 874  KEGTQYALSVTALYASGAGDALFGEGTTLEERGSPQDLVTKDITDTSIGAYWTSAPGMVR 933

Query: 1934 GFQVDAVPANGQTPI-QRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDAST 1992
            G++V            ++ +  D     I  LQP T Y+I ++    +    P+  DA+T
Sbjct: 934  GYRVSWKSLYDDVDTGEKNLPEDAIHTMIENLQPETKYRISVFATYSSGEGEPLTGDATT 993

Query: 1993 AIDAPS-NLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATI 2051
             +   S  L+    T N++ V+W+P   ++  Y + Y +P    +++V +  P VT   +
Sbjct: 994  ELSQDSKTLKVDEETENTMRVTWKPAPGKVVNYRVVY-RPHGRGKQMVAKVPPTVTSTVL 1052

Query: 2052 TGLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQKTPFVTHPGYDTGNGIQLPGTSGQQPS 2111
              L+P T Y I V+                          P Y  G G +L   SG   S
Sbjct: 1053 KRLQPQTTYDITVL--------------------------PIYKMGEG-KLRQGSGTTAS 1085

Query: 2112 VGQQMIFEEHGFRRTTPPTTATPIRHRPRPYPPNVGQEALSQTTISWAPFQ-DTSEYIIS 2170
                  F+     +T+ PT                    +S   ++W P   +   Y ++
Sbjct: 1086 -----RFKSPRNLKTSDPT--------------------MSSFRVTWEPAPGEVKGYKVT 1120

Query: 2171 CHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKD--QQRHKVREEVVTVGNS 2228
             HP G D    +  V     +  L  L  G TY + V  + D  +    V +E+ T+ ++
Sbjct: 1121 FHPTGDDRRLGELVVGPYDNTVVLEELRAGTTYKVNVFGMFDGGESSPLVGQEMTTLSDT 1180



 Score =  161 bits (407), Expect = 8e-39
 Identities = 149/568 (26%), Positives = 249/568 (43%), Gaps = 27/568 (4%)

Query: 727  SVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKY 786
            S +E+T+  F  +W  A + V  + + Y+ +   DE   ++ P+++TSV +  L P   Y
Sbjct: 639  SFSEVTSYGFKTNWSPAGENVFSYHITYKEAAGDDEVTVVE-PASSTSVVLSSLKPETLY 697

Query: 787  IVNVYQISEDGEQSLILSTSQTT--APDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIV 844
            +VNV    EDG  S+ L+  +TT     AP +  V      S  + W++    +  YRI+
Sbjct: 698  LVNVTAEYEDGF-SIPLAGEETTEEVKGAPRNLKVTDETTDSFKITWTQAPGRVLRYRII 756

Query: 845  YSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRS 904
            Y P   G S E+  P      TL +L P  +Y +++     +   TP+      TG   +
Sbjct: 757  YRPVAGGESREVTTPPNQRRRTLENLIPDTKYEVSVIPEYFSGPGTPL------TGNAAT 810

Query: 905  DTV-PSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAE 963
            + V  +PRDL+  + T   + + W+     V  Y V   PV   G   Q + +  +T   
Sbjct: 811  EEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTYTPV--AGGETQEVTVRGDTTNT 868

Query: 964  V-TGLSPGVTYYFKVFAVSHGRESKPLTAQQTT--KLDAPTNLQFVNETDSTVLVRWTPP 1020
            V  GL  G  Y   V A+        L  + TT  +  +P +L   + TD+++   WT  
Sbjct: 869  VLQGLKEGTQYALSVTALYASGAGDALFGEGTTLEERGSPQDLVTKDITDTSIGAYWTSA 928

Query: 1021 RAQITGYRLT-VGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKAT 1079
               + GYR++   L       + N+        + NLQP ++Y +S+ A   + E    T
Sbjct: 929  PGMVRGYRVSWKSLYDDVDTGEKNLPEDAIHTMIENLQPETKYRISVFATYSSGEGEPLT 988

Query: 1080 GVFTTLQPGSSIPPYNTEVTETTIVITWTPAPR--IGFKLGVRP-SQGGEAPREVTSDSG 1136
            G  TT     S      E TE T+ +TW PAP   + +++  RP  +G +   +V     
Sbjct: 989  GDATTELSQDSKTLKVDEETENTMRVTWKPAPGKVVNYRVVYRPHGRGKQMVAKVPPTVT 1048

Query: 1137 SIVVSGLTPGVEYVYTI-QVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSW 1195
            S V+  L P   Y  T+  + + G+ +         +    P NL   ++P      V+W
Sbjct: 1049 STVLKRLQPQTTYDITVLPIYKMGEGKLRQGSGTTASRFKSPRNLK-TSDPTMSSFRVTW 1107

Query: 1196 ERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKE 1255
            E     ++ GY++T  PT G      E VV    ++   + L  G  Y V+V+ + D  E
Sbjct: 1108 E-PAPGEVKGYKVTFHPT-GDDRRLGELVVGPYDNTVVLEELRAGTTYKVNVFGMFDGGE 1165

Query: 1256 SVPISDTIIPEVPQLTDLSFVDITDSSI 1283
            S P+   +  E+  L+D + + I  S +
Sbjct: 1166 SSPL---VGQEMTTLSDTTVMPILSSGM 1190



 Score =  160 bits (405), Expect = 1e-38
 Identities = 151/584 (25%), Positives = 255/584 (43%), Gaps = 28/584 (4%)

Query: 885  ENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPV 944
            E  +S  + I+QE     +   VP P+DL F EVT       W+P    V  Y +     
Sbjct: 611  ELTQSICLRIEQELAAIKKKAYVP-PKDLSFSEVTSYGFKTNWSPAGENVFSYHITYKEA 669

Query: 945  NLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTK--LDAPTN 1002
                E     P S +T   ++ L P   Y   V A      S PL  ++TT+    AP N
Sbjct: 670  AGDDEVTVVEPAS-STSVVLSSLKPETLYLVNVTAEYEDGFSIPLAGEETTEEVKGAPRN 728

Query: 1003 LQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEY 1062
            L+  +ET  +  + WT    ++  YR+       G+ R+    P+  +  L NL P ++Y
Sbjct: 729  LKVTDETTDSFKITWTQAPGRVLRYRIIYRPVAGGESREVTTPPNQRRRTLENLIPDTKY 788

Query: 1063 TVSLVAIKGNQESPKATGVFTTLQ-PGSSIPPYNTEVTETTIVITWTPAPR--IGFKLGV 1119
             VS++    +      TG   T +  G+      ++ T +T+ ++W+ AP     + +  
Sbjct: 789  EVSVIPEYFSGPGTPLTGNAATEEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTY 848

Query: 1120 RPSQGGEAPREVT--SDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPI-VNKVVTPLSP 1176
             P  GGE  +EVT   D+ + V+ GL  G +Y  ++  L      DA       +     
Sbjct: 849  TPVAGGET-QEVTVRGDTTNTVLQGLKEGTQYALSVTALYASGAGDALFGEGTTLEERGS 907

Query: 1177 PTNLHLEANPDTGVLTVSWERSTTPDITGYRIT----TTPTNGQQGNSLEEVVHADQSSC 1232
            P +L  +   DT +   ++  S    + GYR++        +  + N  E+ +H      
Sbjct: 908  PQDLVTKDITDTSI--GAYWTSAPGMVRGYRVSWKSLYDDVDTGEKNLPEDAIHT----- 960

Query: 1233 TFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPEVPQLTDLSFVD-ITDSSIGLRWTPLN 1291
              +NL P  +Y +SV+      E  P++     E+ Q +    VD  T++++ + W P  
Sbjct: 961  MIENLQPETKYRISVFATYSSGEGEPLTGDATTELSQDSKTLKVDEETENTMRVTWKPA- 1019

Query: 1292 SSTIIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTT 1351
               ++ YR+     G G  +    V  +V    +  L+P   YDI+V+ +   GE     
Sbjct: 1020 PGKVVNYRVVYRPHGRGKQMVAK-VPPTVTSTVLKRLQPQTTYDITVLPIYKMGEGKLRQ 1078

Query: 1352 LTQQTA--VPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISP 1409
             +  TA     P +L+ ++    + RVTW P P  ++  + V + P  ++  + EL + P
Sbjct: 1079 GSGTTASRFKSPRNLKTSDPTMSSFRVTWEPAPG-EVKGYKVTFHPTGDDRRLGELVVGP 1137

Query: 1410 SDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPT 1453
             DN VVL  L  GT Y V+V  +++  ES+PL G++ T L   T
Sbjct: 1138 YDNTVVLEELRAGTTYKVNVFGMFDGGESSPLVGQEMTTLSDTT 1181



 Score =  159 bits (403), Expect = 2e-38
 Identities = 201/869 (23%), Positives = 340/869 (39%), Gaps = 73/869 (8%)

Query: 905  DTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPIS-RNTFAE 963
            + V  P +L  +EV+   V + W P  S VTGY+V + P+   G     L +  + T   
Sbjct: 332  EVVEPPSNLIAMEVSSKYVKLNWNPSPSPVTGYKVILTPMT-AGSRQHALSVGPQTTTLS 390

Query: 964  VTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTK-----------LDAPTNLQF-VNETDS 1011
            V  LS    Y   V A+     S+P++  + T+           +D   ++ F V+ + S
Sbjct: 391  VRDLSADTEYQISVSAMKGMTSSEPISIMEKTQPMKVQVECSRGVDIKADIVFLVDGSYS 450

Query: 1012 TVLVRWTPPRA---------QITGYRLTVGL-----------TRRGQPRQYNVGPSVSKY 1051
              +  +   RA         +I+  R+ + L           T +   +  ++  +++ +
Sbjct: 451  IGIANFVKVRAFLEVLVKSFEISPNRVQISLVQYSRDPHTEFTLKKFTKVEDIIEAINTF 510

Query: 1052 PLR----NLQPASEYTVSLVAI--KGNQES-PKATGVFTTLQPGSSIPPYNTEVTETTIV 1104
            P R    N   A  Y    + +  KG++ + PK   + T  +   +      ++  + + 
Sbjct: 511  PYRGGSTNTGKAMTYVREKIFVPSKGSRSNVPKVMILITDGKSSDAFRDPAIKLRNSDVE 570

Query: 1105 ITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDA 1164
            I       +G K  VR      A     +   ++        + +  T  +    ++  A
Sbjct: 571  IF-----AVGVKDAVRSELEAIASPPAETHVFTVEDFDAFQRISFELTQSICLRIEQELA 625

Query: 1165 PIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEV 1224
             I  K   P   P +L        G  T +W      ++  Y IT     G   + +  V
Sbjct: 626  AIKKKAYVP---PKDLSFSEVTSYGFKT-NWS-PAGENVFSYHITYKEAAGD--DEVTVV 678

Query: 1225 VHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS--DTIIPEVPQLTDLSFVDITDSS 1282
              A  +S    +L P   Y V+V    +D  S+P++  +T         +L   D T  S
Sbjct: 679  EPASSTSVVLSSLKPETLYLVNVTAEYEDGFSIPLAGEETTEEVKGAPRNLKVTDETTDS 738

Query: 1283 IGLRWTPLNSSTIIGYRITV--VAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVIT 1340
              + WT      ++ YRI    VA GE     E     +    T+  L P   Y++SVI 
Sbjct: 739  FKITWTQA-PGRVLRYRIIYRPVAGGES---REVTTPPNQRRRTLENLIPDTKYEVSVIP 794

Query: 1341 LINGGESAPTT--LTQQTAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKN 1398
                G   P T     +     P DLR ++    TM+++W+  P   +  +LV Y+PV  
Sbjct: 795  EYFSGPGTPLTGNAATEEVRGNPRDLRVSDPTTSTMKLSWSGAPG-KVKQYLVTYTPVAG 853

Query: 1399 EEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKT--GLDSPTGID 1456
             E   E+++       VL  L  GT+Y +SV+++Y       L G   T     SP  + 
Sbjct: 854  GE-TQEVTVRGDTTNTVLQGLKEGTQYALSVTALYASGAGDALFGEGTTLEERGSPQDLV 912

Query: 1457 FSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYV 1516
              DIT  S   +W +    + GYR+     +      E  +P       + NL P T+Y 
Sbjct: 913  TKDITDTSIGAYWTSAPGMVRGYRVSWKSLYDDVDTGEKNLPEDAIHTMIENLQPETKYR 972

Query: 1517 VSIVALNGREESPLLIGQQST-VSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGE 1575
            +S+ A     E   L G  +T +S   + L+V   T  ++ ++W      V  YR+ Y  
Sbjct: 973  ISVFATYSSGEGEPLTGDATTELSQDSKTLKVDEETENTMRVTWKPAPGKVVNYRVVYRP 1032

Query: 1576 TG-GNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEID 1634
             G G   V +  VP + ++  +  L+P   Y ITV  +   G+     +  S    +   
Sbjct: 1033 HGRGKQMVAK--VPPTVTSTVLKRLQPQTTYDITVLPIYKMGE--GKLRQGSGTTASRFK 1088

Query: 1635 KPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQ 1694
             P  ++ +D   +S  V W P+   V GY+VT  P            GP    + +E L+
Sbjct: 1089 SPRNLKTSDPTMSSFRVTWEPAPGEVKGYKVTFHPTGDDRRLGELVVGPYDNTVVLEELR 1148

Query: 1695 PTVEYVVSVYAQNPSGESQPLVQTAVTNI 1723
                Y V+V+     GES PLV   +T +
Sbjct: 1149 AGTTYKVNVFGMFDGGESSPLVGQEMTTL 1177



 Score =  105 bits (263), Expect = 4e-22
 Identities = 119/490 (24%), Positives = 188/490 (38%), Gaps = 49/490 (10%)

Query: 1803 QPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLA 1862
            Q L   +  A   P DL F++VT       W+P    +  Y   +T KE  G  +   + 
Sbjct: 622  QELAAIKKKAYVPPKDLSFSEVTSYGFKTNWSPAGENVFSY--HITYKEAAGDDEVTVVE 679

Query: 1863 PDSS-SVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTI 1921
            P SS SVV+S L   T Y V+V A  +   S P  G  TT E    PR  +VTD T  + 
Sbjct: 680  PASSTSVVLSSLKPETLYLVNVTAEYEDGFSIPLAGEETTEEVKGAPRNLKVTDETTDSF 739

Query: 1922 TISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNA 1981
             I+W      +  +++   P  G    + T  P+ R  T+  L P T Y++ +     + 
Sbjct: 740  KITWTQAPGRVLRYRIIYRPVAGGESREVTTPPNQRRRTLENLIPDTKYEVSVIPEYFSG 799

Query: 1982 RSSPVVIDAST--AIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEK-PGSPPREV 2038
              +P+  +A+T      P +LR    T +++ +SW     ++  Y++ Y    G   +EV
Sbjct: 800  PGTPLTGNAATEEVRGNPRDLRVSDPTTSTMKLSWSGAPGKVKQYLVTYTPVAGGETQEV 859

Query: 2039 VPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQK----TPFVTHPGY 2094
                R   T   + GL+ GT+Y + V AL  +   + L G   T+++       VT    
Sbjct: 860  T--VRGDTTNTVLQGLKEGTQYALSVTALYASGAGDALFGEGTTLEERGSPQDLVTKDIT 917

Query: 2095 DTGNGIQLPGTSG-------------QQPSVGQQMIFEE--HGFRRTTPPTT-------A 2132
            DT  G       G                  G++ + E+  H       P T       A
Sbjct: 918  DTSIGAYWTSAPGMVRGYRVSWKSLYDDVDTGEKNLPEDAIHTMIENLQPETKYRISVFA 977

Query: 2133 TPIRHRPRPYPPN-------------VGQEALSQTTISWAPFQ-DTSEYIISCHPVGTDE 2178
            T       P   +             V +E  +   ++W P       Y +   P G  +
Sbjct: 978  TYSSGEGEPLTGDATTELSQDSKTLKVDEETENTMRVTWKPAPGKVVNYRVVYRPHGRGK 1037

Query: 2179 EPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHKVREEVVTVGNSVNEGLNQPTD 2238
            + +  +VP T TS  L  L    TY+I V  +      K+R+   T  +      N  T 
Sbjct: 1038 Q-MVAKVPPTVTSTVLKRLQPQTTYDITVLPIYKMGEGKLRQGSGTTASRFKSPRNLKTS 1096

Query: 2239 DSCFDPYTVS 2248
            D     + V+
Sbjct: 1097 DPTMSSFRVT 1106



 Score = 66.6 bits (161), Expect = 3e-10
 Identities = 37/123 (30%), Positives = 64/123 (52%), Gaps = 4/123 (3%)

Query: 800 SLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLP 859
           +L+LS+ +    D P D     +D+ ++ + W++P  PI GYRI   P+ +G + E  L 
Sbjct: 15  ALLLSSIEAEV-DPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTTDGPTKEFTLS 73

Query: 860 ETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQ---QETTGTPRSDTVPSPRDLQFV 916
            +     LS+L P  +Y +TI + +E +ES PV+ Q   Q  + T   +  P   ++Q  
Sbjct: 74  ASTTETLLSELVPETEYVVTITSYDEVEESVPVIGQLTIQTGSSTKPVEKKPGKTEIQKC 133

Query: 917 EVT 919
            V+
Sbjct: 134 SVS 136



 Score = 65.9 bits (159), Expect = 5e-10
 Identities = 75/320 (23%), Positives = 125/320 (39%), Gaps = 32/320 (10%)

Query: 595  GEWHCQPLQ--TYPSSSGP--VEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNS 650
            GE +  P Q  T P S GP  + VF   T    NS  + W+      + +Y + + P   
Sbjct: 2011 GEGNPSPAQGRTLPRS-GPRNLRVFGETT----NSLSVAWDHAD-GPVQQYRIIYSPTVG 2064

Query: 651  VGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNT 710
                +  T+PG  N+  ++ L+P   Y+  +I++ + G                      
Sbjct: 2065 DPIDEYTTVPGRRNNVILQPLQPDTPYKITVIAVYEDGD------------------GGH 2106

Query: 711  VTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPS 770
            +TG       L   +  +++   + F VSW  +   V G+++ Y+    G          
Sbjct: 2107 LTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPSPVLGYKIVYK--PVGSNEPMEAFVG 2164

Query: 771  TATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVR 830
              TS  + +L P   Y VNVY   + G  S+ L+   TT      D    Q+   +  V+
Sbjct: 2165 EMTSYTLHNLNPSTTYDVNVYAQYDSG-LSVPLTDQGTTLYLNVTDLKTYQIGWDTFCVK 2223

Query: 831  WSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQEST 890
            WS P    T YR+  SP+      E+ +  +  S   + L P   Y +T++    N E  
Sbjct: 2224 WS-PHRAATSYRLKLSPADGTRGQEITVRGSETSHCFTGLSPDTDYGVTVFVQTPNLEGP 2282

Query: 891  PVVIQQETTGTPRSDTVPSP 910
             V +++ TT  P       P
Sbjct: 2283 GVSVKEHTTVKPTEAPTEPP 2302



 Score = 59.7 bits (143), Expect = 3e-08
 Identities = 28/85 (32%), Positives = 44/85 (51%), Gaps = 1/85 (1%)

Query: 1632 EIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIE 1691
            E+D PS +    + +N++ + W     P+ GYR+T  P    GPTK  T     TE  + 
Sbjct: 24   EVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTT-DGPTKEFTLSASTTETLLS 82

Query: 1692 GLQPTVEYVVSVYAQNPSGESQPLV 1716
             L P  EYVV++ + +   ES P++
Sbjct: 83   ELVPETEYVVTITSYDEVEESVPVI 107



 Score = 58.9 bits (141), Expect = 6e-08
 Identities = 37/117 (31%), Positives = 59/117 (50%), Gaps = 5/117 (4%)

Query: 996  KLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRN 1055
            ++D P++L F    ++TV + W  P   I GYR+TV  T  G  +++ +  S ++  L  
Sbjct: 24   EVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTTDGPTKEFTLSASTTETLLSE 83

Query: 1056 LQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTI----VITWT 1108
            L P +EY V++ +    +ES    G   T+Q GSS  P   +  +T I    V  WT
Sbjct: 84   LVPETEYVVTITSYDEVEESVPVIGQL-TIQTGSSTKPVEKKPGKTEIQKCSVSAWT 139



 Score = 53.9 bits (128), Expect = 2e-06
 Identities = 29/90 (32%), Positives = 49/90 (54%), Gaps = 2/90 (2%)

Query: 1355 QTAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAV 1414
            +  V PP+DL F  I  +T+ ++WA P    +  + +   P   +    E ++S S    
Sbjct: 22   EAEVDPPSDLNFKIIDENTVHMSWAKPVD-PIVGYRITVDPT-TDGPTKEFTLSASTTET 79

Query: 1415 VLTNLLPGTEYVVSVSSVYEQHESTPLRGR 1444
            +L+ L+P TEYVV+++S  E  ES P+ G+
Sbjct: 80   LLSELVPETEYVVTITSYDEVEESVPVIGQ 109



 Score = 50.1 bits (118), Expect = 3e-05
 Identities = 35/125 (28%), Positives = 58/125 (46%), Gaps = 7/125 (5%)

Query: 1715 LVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGE 1774
            L+ +    +D P  L F  +D +++ ++W  P   +  YR+T     DG  + F      
Sbjct: 17   LLSSIEAEVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTTDGPTKEFTLSAST 76

Query: 1775 EDTAELQGLRPGSEYTVSVVALHDDMESQPLIG-----TQSTAIPAPTDLKFTQVTPTSL 1829
             +T  L  L P +EY V++ +  +  ES P+IG     T S+  P       T++   S+
Sbjct: 77   TETL-LSELVPETEYVVTITSYDEVEESVPVIGQLTIQTGSSTKPVEKKPGKTEIQKCSV 135

Query: 1830 SAQWT 1834
            SA WT
Sbjct: 136  SA-WT 139



 Score = 50.1 bits (118), Expect = 3e-05
 Identities = 31/86 (36%), Positives = 44/86 (51%), Gaps = 1/86 (1%)

Query: 1449 LDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTN 1508
            +D P+ ++F  I  N+  + W  P   I GYRI   P    G  +E  +  S     L+ 
Sbjct: 25   VDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTT-DGPTKEFTLSASTTETLLSE 83

Query: 1509 LTPGTEYVVSIVALNGREESPLLIGQ 1534
            L P TEYVV+I + +  EES  +IGQ
Sbjct: 84   LVPETEYVVTITSYDEVEESVPVIGQ 109



 Score = 48.9 bits (115), Expect = 6e-05
 Identities = 26/96 (27%), Positives = 47/96 (48%), Gaps = 1/96 (1%)

Query: 1805 LIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPD 1864
            L+ +    +  P+DL F  +   ++   W  P   + GYR+ V P    GP KE  L+  
Sbjct: 17   LLSSIEAEVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDP-TTDGPTKEFTLSAS 75

Query: 1865 SSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVT 1900
            ++  ++S L+  T+Y V++ +  +   S P  G +T
Sbjct: 76   TTETLLSELVPETEYVVTITSYDEVEESVPVIGQLT 111



 Score = 45.1 bits (105), Expect = 9e-04
 Identities = 28/96 (29%), Positives = 49/96 (51%), Gaps = 4/96 (4%)

Query: 1164 APIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEE 1223
            A +++ +   + PP++L+ +   D   + +SW +   P I GYRIT  PT    G + E 
Sbjct: 15   ALLLSSIEAEVDPPSDLNFKII-DENTVHMSWAKPVDP-IVGYRITVDPTT--DGPTKEF 70

Query: 1224 VVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPI 1259
             + A  +      L P  EY V++ +  + +ESVP+
Sbjct: 71   TLSASTTETLLSELVPETEYVVTITSYDEVEESVPV 106



 Score = 45.1 bits (105), Expect = 9e-04
 Identities = 23/110 (20%), Positives = 53/110 (48%), Gaps = 1/110 (0%)

Query: 790 VYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSV 849
           + Q+    ++ L    S     + P +    +V    + + W+   +P+TGY+++ +P  
Sbjct: 313 ISQVCSGVDEQLGELVSGEEVVEPPSNLIAMEVSSKYVKLNWNPSPSPVTGYKVILTPMT 372

Query: 850 EGSSTE-LNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQET 898
            GS    L++     ++++ DL    +Y I++ A++    S P+ I ++T
Sbjct: 373 AGSRQHALSVGPQTTTLSVRDLSADTEYQISVSAMKGMTSSEPISIMEKT 422



 Score = 44.3 bits (103), Expect = 0.001
 Identities = 36/131 (27%), Positives = 52/131 (39%), Gaps = 21/131 (16%)

Query: 1530 LLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPG 1589
            LL+       D P DL        ++ +SW  P   +  YRIT   T  + P +EFT+  
Sbjct: 16   LLLSSIEAEVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTT-DGPTKEFTLSA 74

Query: 1590 SKSTATISGLKPGVDYTITVYAV----------------TGRGDSPASSKPISINYRTEI 1633
            S +   +S L P  +Y +T+ +                 TG    P   KP     +TEI
Sbjct: 75   STTETLLSELVPETEYVVTITSYDEVEESVPVIGQLTIQTGSSTKPVEKKP----GKTEI 130

Query: 1634 DKPSQMQVTDV 1644
             K S    TD+
Sbjct: 131  QKCSVSAWTDL 141



 Score = 43.1 bits (100), Expect = 0.003
 Identities = 29/102 (28%), Positives = 46/102 (45%), Gaps = 9/102 (8%)

Query: 1994 IDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITG 2053
            +D PS+L F     N++ +SW  P   I GY I  +     P +         TE  ++ 
Sbjct: 25   VDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTTDGPTKEFTL-SASTTETLLSE 83

Query: 2054 LEPGTEYTIYVIALKNNQKSEPLIGR--------KKTVQKTP 2087
            L P TEY + + +    ++S P+IG+         K V+K P
Sbjct: 84   LVPETEYVVTITSYDEVEESVPVIGQLTIQTGSSTKPVEKKP 125



 Score = 36.2 bits (82), Expect = 0.40
 Identities = 22/103 (21%), Positives = 45/103 (43%), Gaps = 1/103 (0%)

Query: 1886 LKDTLTSRPAQGVVTTLE-NVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANG 1944
            L   L +  A  +++++E  V PP         E T+ +SW    + I G+++   P   
Sbjct: 5    LPPALAALGAALLLSSIEAEVDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTTD 64

Query: 1945 QTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVV 1987
                + T+        ++ L P T+Y + + + ++   S PV+
Sbjct: 65   GPTKEFTLSASTTETLLSELVPETEYVVTITSYDEVEESVPVI 107



 Score = 35.0 bits (79), Expect = 0.90
 Identities = 24/95 (25%), Positives = 38/95 (40%), Gaps = 1/95 (1%)

Query: 907  VPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTG 966
            V  P DL F  + +  V + W  P   + GYR+ V P    G   +    +  T   ++ 
Sbjct: 25   VDPPSDLNFKIIDENTVHMSWAKPVDPIVGYRITVDPTT-DGPTKEFTLSASTTETLLSE 83

Query: 967  LSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPT 1001
            L P   Y   + +     ES P+  Q T +  + T
Sbjct: 84   LVPETEYVVTITSYDEVEESVPVIGQLTIQTGSST 118



 Score = 33.5 bits (75), Expect = 2.6
 Identities = 18/79 (22%), Positives = 37/79 (46%), Gaps = 6/79 (7%)

Query: 738 VSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDG 797
           +SW    D + G+R+  + + +G   ++  L ++ T   + +L+P  +Y+V +    E  
Sbjct: 43  MSWAKPVDPIVGYRITVDPTTDGPTKEF-TLSASTTETLLSELVPETEYVVTITSYDEVE 101

Query: 798 EQ-----SLILSTSQTTAP 811
           E       L + T  +T P
Sbjct: 102 ESVPVIGQLTIQTGSSTKP 120


>gi|153946395 tenascin C precursor [Homo sapiens]
          Length = 2201

 Score =  379 bits (973), Expect = e-104
 Identities = 314/1295 (24%), Positives = 543/1295 (41%), Gaps = 51/1295 (3%)

Query: 814  PPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGS-STELNLPETANSVTLSDLQP 872
            P D  V +V + ++ + W   +  +T Y +VY+P+ EG    +  +P    S  + +L+P
Sbjct: 626  PKDLVVTEVTEETVNLAWDN-EMRVTEYLVVYTPTHEGGLEMQFRVPGDQTSTIIQELEP 684

Query: 873  GVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPES 932
            GV+Y I ++A+ EN++S PV  +  T        +P+P  L+F  + +  V + W P + 
Sbjct: 685  GVEYFIRVFAILENKKSIPVSARVATY-------LPAPEGLKFKSIKETSVEVEWDPLDI 737

Query: 933  AVTGYRVDVIPVNLPGEHGQRLPISR-NTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTA 991
            A   + +    +N   E      + R  T    TGL+PG  Y   +  V +      L  
Sbjct: 738  AFETWEIIFRNMNKEDEGEITKSLRRPETSYRQTGLAPGQEYEISLHIVKNNTRGPGLKR 797

Query: 992  QQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTR-RGQPRQYNVGPSVSK 1050
              TT+LDAP+ ++  + TD+T L+ W  P A+I G  LT G+    G     ++    ++
Sbjct: 798  VTTTRLDAPSQIEVKDVTDTTALITWFKPLAEIDGIELTYGIKDVPGDRTTIDLTEDENQ 857

Query: 1051 YPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTET--TIVITWT 1108
            Y + NL+P +EY VSL++ +G+  S  A   FTT   G   P     V++T  +I + W 
Sbjct: 858  YSIGNLKPDTEYEVSLISRRGDMSSNPAKETFTT---GLDAPRNLRRVSQTDNSITLEWR 914

Query: 1109 --PAPRIGFKLGVRPSQGGE-----APREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQE 1161
               A    +++   P  GG+      P+   + + +  ++GL PG EY   +  +++ +E
Sbjct: 915  NGKAAIDSYRIKYAPISGGDHAEVDVPKSQQATTKT-TLTGLRPGTEYGIGVSAVKEDKE 973

Query: 1162 RDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRIT-TTPTNGQQGNS 1220
             +   +N   T L  P +L +    +T  LT+ W ++       YR+  + PT    G  
Sbjct: 974  SNPATIN-AATELDTPKDLQVSETAETS-LTLLW-KTPLAKFDRYRLNYSLPTGQWVGVQ 1030

Query: 1221 LEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPE-VPQLTDLSFVDIT 1279
            L      + +S     L PG EYNV +   K   +S P       E  P+L +L+  ++ 
Sbjct: 1031 LPR----NTTSYVLRGLEPGQEYNVLLTAEKGRHKSKPARVKASTEQAPELENLTVTEVG 1086

Query: 1280 DSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVI 1339
               + L WT  + +    + I V  A +        V  S+    + GL+    Y +S+ 
Sbjct: 1087 WDGLRLNWTAADQA-YEHFIIQVQEANKVEAARNLTVPGSLRAVDIPGLKAATPYTVSIY 1145

Query: 1340 TLINGGESAPTTLTQQTAVPPPT-DLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKN 1398
             +I G  +   +    T   P   ++    +G D +++ W  P       F ++      
Sbjct: 1146 GVIQGYRTPVLSAEASTGETPNLGEVVVAEVGWDALKLNWTAPEGA-YEYFFIQVQEADT 1204

Query: 1399 EEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTG-IDF 1457
             E    L++     +  L  L   T Y +++  V +   +TPL     T      G +  
Sbjct: 1205 VEAAQNLTVPGGLRSTDLPGLKAATHYTITIRGVTQDFSTTPLSVEVLTEEVPDMGNLTV 1264

Query: 1458 SDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVV 1517
            ++++ ++  ++W  P  T   + I+              VP S  S+ +  L  GT Y V
Sbjct: 1265 TEVSWDALRLNWTTPDGTYDQFTIQVQEADQVEEAHNLTVPGSLRSMEIPGLRAGTPYTV 1324

Query: 1518 SIVA-LNGREESPLLIGQQSTVSDVPR--DLEVVAATPTSLLISWDAPAVTVRYYRITYG 1574
            ++   + G    PL +  +    D+P+  DL V       L ++W A      ++ I   
Sbjct: 1325 TLHGEVRGHSTRPLAV--EVVTEDLPQLGDLAVSEVGWDGLRLNWTAADNAYEHFVIQVQ 1382

Query: 1575 ETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEID 1634
            E       Q  T+PGS     I GL+    Y +++Y V     +P  S   S     EI 
Sbjct: 1383 EVNKVEAAQNLTLPGSLRAVDIPGLEAATPYRVSIYGVIRGYRTPVLSAEASTAKEPEI- 1441

Query: 1635 KPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQ 1694
                + V+D+   S ++ W+ +      + +     N    T        +    I GL 
Sbjct: 1442 --GNLNVSDITPESFNLSWMATDGIFETFTIEIIDSNRLLETVEYNISGAERTAHISGLP 1499

Query: 1695 PTVEYVVSVYAQNPSGESQPLVQTAVTN-IDRPKGLAFTDVDVDSIKIAWESPQGQVSRY 1753
            P+ +++V +    PS  ++ +  TA T  +   + L  +D++     ++W + +     +
Sbjct: 1500 PSTDFIVYLSGLAPSIRTKTISATATTEALPLLENLTISDINPYGFTVSWMASENAFDSF 1559

Query: 1754 RVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQST-A 1812
             VT       +        G +   EL+GL  G  Y V V       +++PL     T A
Sbjct: 1560 LVTVVDSGKLLDPQEFTLSGTQRKLELRGLITGIGYEVMVSGFTQGHQTKPLRAEIVTEA 1619

Query: 1813 IPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSG 1872
             P   +L  +  TP      WT        + +++   +K     EI L     +  ++G
Sbjct: 1620 EPEVDNLLVSDATPDGFRLSWTADEGVFDNFVLKIRDTKKQSEPLEITLLAPERTRDITG 1679

Query: 1873 LMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETI 1932
            L  AT+YE+ +Y +     S+    + TT   +  P+    +D TE + T+SWR  T  +
Sbjct: 1680 LREATEYEIELYGISKGRRSQTVSAIATTA--MGSPKEVIFSDITENSATVSWRAPTAQV 1737

Query: 1933 TGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDAST 1992
              F++  VP  G TP   T+        +  L PG +Y + +  +     S PV    +T
Sbjct: 1738 ESFRITYVPITGGTPSMVTVDGTKTQTRLVKLIPGVEYLVSIIAMKGFEESEPVSGSFTT 1797

Query: 1993 AIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATIT 2052
            A+D PS L     T +  L  WQP  A +  Y+I Y   G    E+         E  +T
Sbjct: 1798 ALDGPSGLVTANITDSEALARWQPAIATVDSYVISY--TGEKVPEITRTVSGNTVEYALT 1855

Query: 2053 GLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQKTP 2087
             LEP TEYT+ + A K  QKS  +  +  T   +P
Sbjct: 1856 DLEPATEYTLRIFAEKGPQKSSTITAKFTTDLDSP 1890



 Score =  366 bits (939), Expect = e-100
 Identities = 337/1402 (24%), Positives = 598/1402 (42%), Gaps = 82/1402 (5%)

Query: 609  SGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTI 668
            S P ++ +TE   +  +  + W+      +++Y++ + P +  G   +  +PG   S  I
Sbjct: 624  SPPKDLVVTEVTEETVN--LAWD--NEMRVTEYLVVYTPTHEGGLEMQFRVPGDQTSTII 679

Query: 669  KGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESV 728
            + L+PGV Y  ++ +I +                S PV++   T    P           
Sbjct: 680  QELEPGVEYFIRVFAILE-------------NKKSIPVSARVATYLPAP------EGLKF 720

Query: 729  TEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYL-DLPSTATSVNIPDLLPGRKYI 787
              I  +S  V W         + + +    + DE +    L    TS     L PG++Y 
Sbjct: 721  KSIKETSVEVEWDPLDIAFETWEIIFRNMNKEDEGEITKSLRRPETSYRQTGLAPGQEYE 780

Query: 788  VNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYS- 846
            ++++ I ++  +   L    TT  DAP    V  V DT+ ++ W +P A I G  + Y  
Sbjct: 781  ISLH-IVKNNTRGPGLKRVTTTRLDAPSQIEVKDVTDTTALITWFKPLAEIDGIELTYGI 839

Query: 847  PSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDT 906
              V G  T ++L E  N  ++ +L+P  +Y +++ +   +  S P   +  TTG      
Sbjct: 840  KDVPGDRTTIDLTEDENQYSIGNLKPDTEYEVSLISRRGDMSSNPAK-ETFTTG------ 892

Query: 907  VPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQ-RLPISRN--TFAE 963
            + +PR+L+ V  TD  +T+ W   ++A+  YR+   P++  G+H +  +P S+   T   
Sbjct: 893  LDAPRNLRRVSQTDNSITLEWRNGKAAIDSYRIKYAPIS-GGDHAEVDVPKSQQATTKTT 951

Query: 964  VTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQ 1023
            +TGL PG  Y   V AV   +ES P T    T+LD P +LQ     ++++ + W  P A+
Sbjct: 952  LTGLRPGTEYGIGVSAVKEDKESNPATINAATELDTPKDLQVSETAETSLTLLWKTPLAK 1011

Query: 1024 ITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFT 1083
               YRL   L   GQ     +  + + Y LR L+P  EY V L A KG  +S  A    +
Sbjct: 1012 FDRYRLNYSLPT-GQWVGVQLPRNTTSYVLRGLEPGQEYNVLLTAEKGRHKSKPARVKAS 1070

Query: 1084 TLQPGSSIPPYNTEVTETTIVITWTPAPRI--GFKLGVRPSQGGEAPREVTSDSG--SIV 1139
            T Q         TEV    + + WT A +    F + V+ +   EA R +T      ++ 
Sbjct: 1071 TEQAPELENLTVTEVGWDGLRLNWTAADQAYEHFIIQVQEANKVEAARNLTVPGSLRAVD 1130

Query: 1140 VSGLTPGVEYVYTIQVLRDGQERDAPIVN-KVVTPLSPPTNLHLEANPDTGVLTVSWERS 1198
            + GL     Y  +I  +  G     P+++ +  T  +P     + A      L ++W   
Sbjct: 1131 IPGLKAATPYTVSIYGVIQGYR--TPVLSAEASTGETPNLGEVVVAEVGWDALKLNW--- 1185

Query: 1199 TTPDITGYRITTTPTNGQQGNSLEEV----VHADQSSCTFDNLSPGLEYNVSVYTVKDDK 1254
            T P+   Y         Q+ +++E      V     S     L     Y +++  V  D 
Sbjct: 1186 TAPE-GAYEYFFIQV--QEADTVEAAQNLTVPGGLRSTDLPGLKAATHYTITIRGVTQDF 1242

Query: 1255 ESVPIS-DTIIPEVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIFE 1313
             + P+S + +  EVP + +L+  +++  ++ L WT  +  T   + I V  A +      
Sbjct: 1243 STTPLSVEVLTEEVPDMGNLTVTEVSWDALRLNWTTPDG-TYDQFTIQVQEADQVEEAHN 1301

Query: 1314 DFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTA-VPPPTDLRFTNIGPD 1372
              V  S+    + GL  G  Y +++   + G  + P  +   T  +P   DL  + +G D
Sbjct: 1302 LTVPGSLRSMEIPGLRAGTPYTVTLHGEVRGHSTRPLAVEVVTEDLPQLGDLAVSEVGWD 1361

Query: 1373 TMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSV 1432
             +R+ W    +    +F+++   V   E    L++  S  AV +  L   T Y VS+  V
Sbjct: 1362 GLRLNWTAADNA-YEHFVIQVQEVNKVEAAQNLTLPGSLRAVDIPGLEAATPYRVSIYGV 1420

Query: 1433 YEQHESTPLRGRQKTGLDSPTG-IDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGR 1491
               + +  L     T  +   G ++ SDIT  SF + W+A       + I     +    
Sbjct: 1421 IRGYRTPVLSAEASTAKEPEIGNLNVSDITPESFNLSWMATDGIFETFTIEIIDSNRLLE 1480

Query: 1492 PREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVP--RDLEVVA 1549
              E  +  +  +  ++ L P T+++V +  L     +   I   +T   +P   +L +  
Sbjct: 1481 TVEYNISGAERTAHISGLPPSTDFIVYLSGLAPSIRTKT-ISATATTEALPLLENLTISD 1539

Query: 1550 ATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITV 1609
              P    +SW A       + +T  ++G     QEFT+ G++    + GL  G+ Y + V
Sbjct: 1540 INPYGFTVSWMASENAFDSFLVTVVDSGKLLDPQEFTLSGTQRKLELRGLITGIGYEVMV 1599

Query: 1610 YAVTGRGDSPASSKPISINYRTEID-KPSQMQVTDVQDNSISVKWLPSSSPVTGY--RVT 1666
               T        +KP+     TE + +   + V+D   +   + W         +  ++ 
Sbjct: 1600 SGFT----QGHQTKPLRAEIVTEAEPEVDNLLVSDATPDGFRLSWTADEGVFDNFVLKIR 1655

Query: 1667 TTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRP 1726
             T K    P +     P++T   I GL+   EY + +Y  +    SQ +   A T +  P
Sbjct: 1656 DTKKQSE-PLEITLLAPERTR-DITGLREATEYEIELYGISKGRRSQTVSAIATTAMGSP 1713

Query: 1727 KGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPG 1786
            K + F+D+  +S  ++W +P  QV  +R+TY     G   +    DG +    L  L PG
Sbjct: 1714 KEVIFSDITENSATVSWRAPTAQVESFRITYVPITGGTPSMVTV-DGTKTQTRLVKLIPG 1772

Query: 1787 SEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVR 1846
             EY VS++A+    ES+P+ G+ +TA+  P+ L    +T +   A+W P    +  Y + 
Sbjct: 1773 VEYLVSIIAMKGFEESEPVSGSFTTALDGPSGLVTANITDSEALARWQPAIATVDSYVIS 1832

Query: 1847 VTPKEKTGPMKEINLAPDSSSV--VVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLEN 1904
             T ++    + EI      ++V   ++ L  AT+Y + ++A K    S       TT  +
Sbjct: 1833 YTGEK----VPEITRTVSGNTVEYALTDLEPATEYTLRIFAEKGPQKSSTITAKFTT--D 1886

Query: 1905 VSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGL 1964
            +  PR    T+    T  ++WR    ++TG+ +     +G T  +  + PD  SY++  L
Sbjct: 1887 LDSPRDLTATEVQSETALLTWRPPRASVTGYLLVYESVDG-TVKEVIVGPDTTSYSLADL 1945

Query: 1965 QPGTDYKIYLYTLNDNARSSPV 1986
             P T Y   +  LN   RS+ +
Sbjct: 1946 SPSTHYTAKIQALNGPLRSNMI 1967



 Score =  337 bits (865), Expect = 6e-92
 Identities = 310/1230 (25%), Positives = 516/1230 (41%), Gaps = 53/1230 (4%)

Query: 907  VPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTG 966
            V  P+DL   EVT+  V + W   E  VT Y V   P +  G   Q       T   +  
Sbjct: 623  VSPPKDLVVTEVTEETVNLAW-DNEMRVTEYLVVYTPTHEGGLEMQFRVPGDQTSTIIQE 681

Query: 967  LSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITG 1026
            L PGV Y+ +VFA+   ++S P++A+  T L AP  L+F +  +++V V W P       
Sbjct: 682  LEPGVEYFIRVFAILENKKSIPVSARVATYLPAPEGLKFKSIKETSVEVEWDPLDIAFET 741

Query: 1027 YRL---TVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFT 1083
            + +    +     G+  +    P  S Y    L P  EY +SL  +K N   P    V T
Sbjct: 742  WEIIFRNMNKEDEGEITKSLRRPETS-YRQTGLAPGQEYEISLHIVKNNTRGPGLKRVTT 800

Query: 1084 T-LQPGSSIPPYNTEVTETTIVITW-TPAPRI-GFKL--GVRPSQGGEAPREVTSDSGSI 1138
            T L   S I     +VT+TT +ITW  P   I G +L  G++   G     ++T D    
Sbjct: 801  TRLDAPSQIEV--KDVTDTTALITWFKPLAEIDGIELTYGIKDVPGDRTTIDLTEDENQY 858

Query: 1139 VVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERS 1198
             +  L P  EY  ++ + R G     P      T L  P NL   +  D  + T+ W R+
Sbjct: 859  SIGNLKPDTEYEVSL-ISRRGDMSSNPAKETFTTGLDAPRNLRRVSQTDNSI-TLEW-RN 915

Query: 1199 TTPDITGYRITTTPTNGQQGNSLEEVVHADQ---SSCTFDNLSPGLEYNVSVYTVKDDKE 1255
                I  YRI   P +G  G+  E  V   Q   +  T   L PG EY + V  VK+DKE
Sbjct: 916  GKAAIDSYRIKYAPISG--GDHAEVDVPKSQQATTKTTLTGLRPGTEYGIGVSAVKEDKE 973

Query: 1256 SVPISDTIIPEVPQLTDLSFVDITDSSIGLRW-TPLNSSTIIGYRITV-VAAGEGIPIFE 1313
            S P +     E+    DL   +  ++S+ L W TPL  +    YR+   +  G+ + +  
Sbjct: 974  SNPATINAATELDTPKDLQVSETAETSLTLLWKTPL--AKFDRYRLNYSLPTGQWVGV-- 1029

Query: 1314 DFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAVPPPTD-LRFTNIGPD 1372
              +  +   Y + GLEPG +Y++ +       +S P  +   T   P  + L  T +G D
Sbjct: 1030 -QLPRNTTSYVLRGLEPGQEYNVLLTAEKGRHKSKPARVKASTEQAPELENLTVTEVGWD 1088

Query: 1373 TMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSV 1432
             +R+ W         +F+++       E    L++  S  AV +  L   T Y VS+  V
Sbjct: 1089 GLRLNWTAADQA-YEHFIIQVQEANKVEAARNLTVPGSLRAVDIPGLKAATPYTVSIYGV 1147

Query: 1433 YEQHESTPLRGRQKTGLDSPTG-IDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGR 1491
             + + +  L     TG     G +  +++  ++  ++W AP      + I+         
Sbjct: 1148 IQGYRTPVLSAEASTGETPNLGEVVVAEVGWDALKLNWTAPEGAYEYFFIQVQEADTVEA 1207

Query: 1492 PREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVP--RDLEVVA 1549
             +   VP    S  L  L   T Y ++I  +  ++ S   +  +    +VP   +L V  
Sbjct: 1208 AQNLTVPGGLRSTDLPGLKAATHYTITIRGVT-QDFSTTPLSVEVLTEEVPDMGNLTVTE 1266

Query: 1550 ATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITV 1609
             +  +L ++W  P  T   + I   E          TVPGS  +  I GL+ G  YT+T+
Sbjct: 1267 VSWDALRLNWTTPDGTYDQFTIQVQEADQVEEAHNLTVPGSLRSMEIPGLRAGTPYTVTL 1326

Query: 1610 YAVTGRGDSPASSKPISINYRTE-IDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTT 1668
            +    RG    S++P+++   TE + +   + V++V  + + + W  + +    + +   
Sbjct: 1327 HGEV-RGH---STRPLAVEVVTEDLPQLGDLAVSEVGWDGLRLNWTAADNAYEHFVIQVQ 1382

Query: 1669 PKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPK- 1727
              N     +  T       + I GL+    Y VS+Y     G   P++    +    P+ 
Sbjct: 1383 EVNKVEAAQNLTLPGSLRAVDIPGLEAATPYRVSIYGV-IRGYRTPVLSAEASTAKEPEI 1441

Query: 1728 -GLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPG 1786
              L  +D+  +S  ++W +  G    + +        +  +     G E TA + GL P 
Sbjct: 1442 GNLNVSDITPESFNLSWMATDGIFETFTIEIIDSNRLLETVEYNISGAERTAHISGLPPS 1501

Query: 1787 SEYTVSVVALHDDMESQPLIGTQST-AIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRV 1845
            +++ V +  L   + ++ +  T +T A+P   +L  + + P   +  W         + V
Sbjct: 1502 TDFIVYLSGLAPSIRTKTISATATTEALPLLENLTISDINPYGFTVSWMASENAFDSFLV 1561

Query: 1846 RVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENV 1905
             V    K    +E  L+     + + GL+    YEV V        ++P +  + T E  
Sbjct: 1562 TVVDSGKLLDPQEFTLSGTQRKLELRGLITGIGYEVMVSGFTQGHQTKPLRAEIVT-EAE 1620

Query: 1906 SPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQT-PIQRTIKPDVRSYTITGL 1964
                   V+DAT     +SW         F +       Q+ P++ T+    R+  ITGL
Sbjct: 1621 PEVDNLLVSDATPDGFRLSWTADEGVFDNFVLKIRDTKKQSEPLEITLLAPERTRDITGL 1680

Query: 1965 QPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGY 2024
            +  T+Y+I LY ++   RS  V   A+TA+ +P  + F   T NS  VSW+ P A++  +
Sbjct: 1681 REATEYEIELYGISKGRRSQTVSAIATTAMGSPKEVIFSDITENSATVSWRAPTAQVESF 1740

Query: 2025 IIKYE--KPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKT 2082
             I Y     G+P    V   +   T+  +  L PG EY + +IA+K  ++SEP+ G   T
Sbjct: 1741 RITYVPITGGTPSMVTVDGTK---TQTRLVKLIPGVEYLVSIIAMKGFEESEPVSGSFTT 1797

Query: 2083 VQKTPFVTHPGYDTGNGIQLPGTSGQQPSV 2112
                P     G  T N       +  QP++
Sbjct: 1798 ALDGP----SGLVTANITDSEALARWQPAI 1823



 Score =  334 bits (856), Expect = 7e-91
 Identities = 315/1382 (22%), Positives = 570/1382 (41%), Gaps = 84/1382 (6%)

Query: 728  VTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYI 787
            VTE+T  +  ++W +    V+ + V Y  + EG       +P   TS  I +L PG +Y 
Sbjct: 631  VTEVTEETVNLAWDNEM-RVTEYLVVYTPTHEGGLEMQFRVPGDQTSTIIQELEPGVEYF 689

Query: 788  VNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVY-- 845
            + V+ I E+ ++S+ +S    T   AP       + +TS+ V W         + I++  
Sbjct: 690  IRVFAILEN-KKSIPVSARVATYLPAPEGLKFKSIKETSVEVEWDPLDIAFETWEIIFRN 748

Query: 846  -SPSVEGSSTE-LNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPR 903
             +   EG  T+ L  PET+   T   L PG +Y I+++ V+ N     +    +   T R
Sbjct: 749  MNKEDEGEITKSLRRPETSYRQT--GLAPGQEYEISLHIVKNNTRGPGL----KRVTTTR 802

Query: 904  SDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQ-RLPISRNTFA 962
             D   +P  ++  +VTD    I W  P + + G  +     ++PG+     L    N ++
Sbjct: 803  LD---APSQIEVKDVTDTTALITWFKPLAEIDGIELTYGIKDVPGDRTTIDLTEDENQYS 859

Query: 963  EVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRA 1022
             +  L P   Y   + +      S P     TT LDAP NL+ V++TD+++ + W   +A
Sbjct: 860  -IGNLKPDTEYEVSLISRRGDMSSNPAKETFTTGLDAPRNLRRVSQTDNSITLEWRNGKA 918

Query: 1023 QITGYRLTVGLTRRGQPRQYNVGPS---VSKYPLRNLQPASEYTVSLVAIKGNQESPKAT 1079
             I  YR+       G   + +V  S    +K  L  L+P +EY + + A+K ++ES  AT
Sbjct: 919  AIDSYRIKYAPISGGDHAEVDVPKSQQATTKTTLTGLRPGTEYGIGVSAVKEDKESNPAT 978

Query: 1080 -GVFTTLQPGSSIPPYNTEVTETTIVITW-TPAP-----RIGFKLGVRPSQGGEAPREVT 1132
                T L     +    +E  ET++ + W TP       R+ + L      G + PR  T
Sbjct: 979  INAATELDTPKDLQV--SETAETSLTLLWKTPLAKFDRYRLNYSLPTGQWVGVQLPRNTT 1036

Query: 1133 SDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLT 1192
            S     V+ GL PG EY   +     G+ +  P   K  T  +P          +  V  
Sbjct: 1037 S----YVLRGLEPGQEY-NVLLTAEKGRHKSKPARVKASTEQAPELE-------NLTVTE 1084

Query: 1193 VSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPG------------ 1240
            V W+        G R+  T  +    + + +V  A++     +   PG            
Sbjct: 1085 VGWD--------GLRLNWTAADQAYEHFIIQVQEANKVEAARNLTVPGSLRAVDIPGLKA 1136

Query: 1241 -LEYNVSVY-TVKDDKESVPISDTIIPEVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGY 1298
               Y VS+Y  ++  +  V  ++    E P L ++   ++   ++ L WT    +    Y
Sbjct: 1137 ATPYTVSIYGVIQGYRTPVLSAEASTGETPNLGEVVVAEVGWDALKLNWTAPEGA--YEY 1194

Query: 1299 RITVVAAGEGIPIFEDF-VDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTA 1357
                V   + +   ++  V   +    + GL+    Y I++  +     + P ++   T 
Sbjct: 1195 FFIQVQEADTVEAAQNLTVPGGLRSTDLPGLKAATHYTITIRGVTQDFSTTPLSVEVLTE 1254

Query: 1358 -VPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVL 1416
             VP   +L  T +  D +R+ W  P       F ++       E+   L++  S  ++ +
Sbjct: 1255 EVPDMGNLTVTEVSWDALRLNWTTPDGT-YDQFTIQVQEADQVEEAHNLTVPGSLRSMEI 1313

Query: 1417 TNLLPGTEYVVSVSSVYEQHESTPLRGRQKT-GLDSPTGIDFSDITANSFTVHWIAPRAT 1475
              L  GT Y V++      H + PL     T  L     +  S++  +   ++W A    
Sbjct: 1314 PGLRAGTPYTVTLHGEVRGHSTRPLAVEVVTEDLPQLGDLAVSEVGWDGLRLNWTAADNA 1373

Query: 1476 ITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQ 1535
               + I+    +     +   +P S  ++ +  L   T Y VSI  +     +P+L  + 
Sbjct: 1374 YEHFVIQVQEVNKVEAAQNLTLPGSLRAVDIPGLEAATPYRVSIYGVIRGYRTPVLSAEA 1433

Query: 1536 STVSDVP-RDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTA 1594
            ST  +    +L V   TP S  +SW A       + I   ++       E+ + G++ TA
Sbjct: 1434 STAKEPEIGNLNVSDITPESFNLSWMATDGIFETFTIEIIDSNRLLETVEYNISGAERTA 1493

Query: 1595 TISGLKPGVDYTITVYAVTGRGDSPA-SSKPISINYRTE-IDKPSQMQVTDVQDNSISVK 1652
             ISGL P  D+ + +      G +P+  +K IS    TE +     + ++D+     +V 
Sbjct: 1494 HISGLPPSTDFIVYL-----SGLAPSIRTKTISATATTEALPLLENLTISDINPYGFTVS 1548

Query: 1653 WLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGES 1712
            W+ S +    + VT          +  T    Q ++ + GL   + Y V V       ++
Sbjct: 1549 WMASENAFDSFLVTVVDSGKLLDPQEFTLSGTQRKLELRGLITGIGYEVMVSGFTQGHQT 1608

Query: 1713 QPLVQTAVTNID-RPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAP 1771
            +PL    VT  +     L  +D   D  +++W + +G    + +     +     L    
Sbjct: 1609 KPLRAEIVTEAEPEVDNLLVSDATPDGFRLSWTADEGVFDNFVLKIRDTKKQSEPLEITL 1668

Query: 1772 DGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSA 1831
               E T ++ GLR  +EY + +  +     SQ +    +TA+ +P ++ F+ +T  S + 
Sbjct: 1669 LAPERTRDITGLREATEYEIELYGISKGRRSQTVSAIATTAMGSPKEVIFSDITENSATV 1728

Query: 1832 QWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLT 1891
             W  P  Q+  +R+   P     P   + +    +   +  L+   +Y VS+ A+K    
Sbjct: 1729 SWRAPTAQVESFRITYVPITGGTPSM-VTVDGTKTQTRLVKLIPGVEYLVSIIAMKGFEE 1787

Query: 1892 SRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRT 1951
            S P  G  TT   +  P      + T++     W+    T+  + + +        I RT
Sbjct: 1788 SEPVSGSFTTA--LDGPSGLVTANITDSEALARWQPAIATVDSYVI-SYTGEKVPEITRT 1844

Query: 1952 IKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLL 2011
            +  +   Y +T L+P T+Y + ++      +SS +    +T +D+P +L        + L
Sbjct: 1845 VSGNTVEYALTDLEPATEYTLRIFAEKGPQKSSTITAKFTTDLDSPRDLTATEVQSETAL 1904

Query: 2012 VSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQ 2071
            ++W+PPRA +TGY++ YE      +EV+    P  T  ++  L P T YT  + AL    
Sbjct: 1905 LTWRPPRASVTGYLLVYESVDGTVKEVI--VGPDTTSYSLADLSPSTHYTAKIQALNGPL 1962

Query: 2072 KS 2073
            +S
Sbjct: 1963 RS 1964



 Score =  314 bits (805), Expect = 6e-85
 Identities = 310/1276 (24%), Positives = 535/1276 (41%), Gaps = 96/1276 (7%)

Query: 665  SYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVAT 724
            SY   GL PG  YE  L  ++               +T  P      T      S +   
Sbjct: 767  SYRQTGLAPGQEYEISLHIVKN--------------NTRGPGLKRVTTTRLDAPSQI--- 809

Query: 725  SESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGR 784
               V ++T ++ +++W      + G  + Y + +   +   +DL       +I +L P  
Sbjct: 810  --EVKDVTDTTALITWFKPLAEIDGIELTYGIKDVPGDRTTIDLTEDENQYSIGNLKPDT 867

Query: 785  KYIVNVYQISEDGEQSLILSTSQ-TTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRI 843
            +Y V++  IS  G+ S   +    TT  DAP +       D SI + W   +A I  YRI
Sbjct: 868  EYEVSL--ISRRGDMSSNPAKETFTTGLDAPRNLRRVSQTDNSITLEWRNGKAAIDSYRI 925

Query: 844  VYSPSVEGSSTELNLPETANSVT---LSDLQPGVQYNITIYAVEENQESTPVVIQQETTG 900
             Y+P   G   E+++P++  + T   L+ L+PG +Y I + AV+E++ES P  I   T  
Sbjct: 926  KYAPISGGDHAEVDVPKSQQATTKTTLTGLRPGTEYGIGVSAVKEDKESNPATINAATE- 984

Query: 901  TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT 960
                  + +P+DLQ  E  +  +T++W  P +    YR++    +LP      + + RNT
Sbjct: 985  ------LDTPKDLQVSETAETSLTLLWKTPLAKFDRYRLNY---SLPTGQWVGVQLPRNT 1035

Query: 961  FAEVT-GLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPT--NLQFVNETDSTVLVRW 1017
             + V  GL PG  Y   + A     +SKP   + +T+  AP   NL         + + W
Sbjct: 1036 TSYVLRGLEPGQEYNVLLTAEKGRHKSKPARVKASTE-QAPELENLTVTEVGWDGLRLNW 1094

Query: 1018 TPPRAQITGYRLTVGLTRRGQP-RQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESP 1076
            T        + + V    + +  R   V  S+    +  L+ A+ YTVS+  +     +P
Sbjct: 1095 TAADQAYEHFIIQVQEANKVEAARNLTVPGSLRAVDIPGLKAATPYTVSIYGVIQGYRTP 1154

Query: 1077 KATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFK---LGVRPSQGGEAPREVTS 1133
              +   +T +  +       EV    + + WT AP   ++   + V+ +   EA + +T 
Sbjct: 1155 VLSAEASTGETPNLGEVVVAEVGWDALKLNWT-APEGAYEYFFIQVQEADTVEAAQNLTV 1213

Query: 1134 DSG--SIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVL 1191
              G  S  + GL     Y  TI+    G  +D        TPLS    +  E  PD G L
Sbjct: 1214 PGGLRSTDLPGLKAATHYTITIR----GVTQDFS-----TTPLS--VEVLTEEVPDMGNL 1262

Query: 1192 TV---SWERS----TTPDITGYRITTTPTNGQQGNSLEEV----VHADQSSCTFDNLSPG 1240
            TV   SW+      TTPD T  + T      Q+ + +EE     V     S     L  G
Sbjct: 1263 TVTEVSWDALRLNWTTPDGTYDQFTIQV---QEADQVEEAHNLTVPGSLRSMEIPGLRAG 1319

Query: 1241 LEYNVSVYTVKDDKESVPISDTIIPE-VPQLTDLSFVDITDSSIGLRWTPLNSS----TI 1295
              Y V+++       + P++  ++ E +PQL DL+  ++    + L WT  +++     I
Sbjct: 1320 TPYTVTLHGEVRGHSTRPLAVEVVTEDLPQLGDLAVSEVGWDGLRLNWTAADNAYEHFVI 1379

Query: 1296 IGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQ 1355
                +  V A + + +       S+    + GLE    Y +S+  +I G  +   +    
Sbjct: 1380 QVQEVNKVEAAQNLTL-----PGSLRAVDIPGLEAATPYRVSIYGVIRGYRTPVLSAEAS 1434

Query: 1356 TAVPPPT-DLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAV 1414
            TA  P   +L  ++I P++  ++W     I  T F +         +  E +IS ++   
Sbjct: 1435 TAKEPEIGNLNVSDITPESFNLSWMATDGIFET-FTIEIIDSNRLLETVEYNISGAERTA 1493

Query: 1415 VLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKT-GLDSPTGIDFSDITANSFTVHWIAPR 1473
             ++ L P T+++V +S +     +  +     T  L     +  SDI    FTV W+A  
Sbjct: 1494 HISGLPPSTDFIVYLSGLAPSIRTKTISATATTEALPLLENLTISDINPYGFTVSWMASE 1553

Query: 1474 ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN-GREESPLLI 1532
                 + +          P+E  +  ++  + L  L  G  Y V +     G +  PL  
Sbjct: 1554 NAFDSFLVTVVDSGKLLDPQEFTLSGTQRKLELRGLITGIGYEVMVSGFTQGHQTKPLRA 1613

Query: 1533 GQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKS 1592
               +       +L V  ATP    +SW A       + +   +T   S   E T+   + 
Sbjct: 1614 EIVTEAEPEVDNLLVSDATPDGFRLSWTADEGVFDNFVLKIRDTKKQSEPLEITLLAPER 1673

Query: 1593 TATISGLKPGVDYTITVYAVT-GRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISV 1651
            T  I+GL+   +Y I +Y ++ GR      S+ +S    T +  P ++  +D+ +NS +V
Sbjct: 1674 TRDITGLREATEYEIELYGISKGR-----RSQTVSAIATTAMGSPKEVIFSDITENSATV 1728

Query: 1652 KWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE 1711
             W   ++ V  +R+T  P  G  P+     G  +T+  +  L P VEY+VS+ A     E
Sbjct: 1729 SWRAPTAQVESFRITYVPITGGTPSMVTVDGT-KTQTRLVKLIPGVEYLVSIIAMKGFEE 1787

Query: 1712 SQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAP 1771
            S+P+  +  T +D P GL   ++        W+     V  Y ++Y+  +  + E+    
Sbjct: 1788 SEPVSGSFTTALDGPSGLVTANITDSEALARWQPAIATVDSYVISYTGEK--VPEITRTV 1845

Query: 1772 DGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSA 1831
             G      L  L P +EYT+ + A     +S  +    +T + +P DL  T+V   +   
Sbjct: 1846 SGNTVEYALTDLEPATEYTLRIFAEKGPQKSSTITAKFTTDLDSPRDLTATEVQSETALL 1905

Query: 1832 QWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLT 1891
             W PP   +TGY +    +   G +KE+ + PD++S  ++ L  +T Y   + AL   L 
Sbjct: 1906 TWRPPRASVTGYLL--VYESVDGTVKEVIVGPDTTSYSLADLSPSTHYTAKIQALNGPLR 1963

Query: 1892 SRPAQGVVTTLENVSP 1907
            S   Q + TT+  + P
Sbjct: 1964 SNMIQTIFTTIGLLYP 1979



 Score =  224 bits (571), Expect = 8e-58
 Identities = 238/1052 (22%), Positives = 418/1052 (39%), Gaps = 91/1052 (8%)

Query: 1266 EVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIFEDFVDSSVGYYTV 1325
            EV    DL   ++T+ ++ L W   N   +  Y +      EG    +  V        +
Sbjct: 622  EVSPPKDLVVTEVTEETVNLAWD--NEMRVTEYLVVYTPTHEGGLEMQFRVPGDQTSTII 679

Query: 1326 TGLEPGIDYDISVITLINGGESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAPPPSID 1385
              LEPG++Y I V  ++   +S P +    T +P P  L+F +I   ++ V W P     
Sbjct: 680  QELEPGVEYFIRVFAILENKKSIPVSARVATYLPAPEGLKFKSIKETSVEVEWDPLDIAF 739

Query: 1386 LTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQ 1445
             T  ++  +  K +E     S+   + +   T L PG EY +S+  V        L+   
Sbjct: 740  ETWEIIFRNMNKEDEGEITKSLRRPETSYRQTGLAPGQEYEISLHIVKNNTRGPGLKRVT 799

Query: 1446 KTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSIT 1505
             T LD+P+ I+  D+T  +  + W  P A I G  + +  +   G      +    N  +
Sbjct: 800  TTRLDAPSQIEVKDVTDTTALITWFKPLAEIDGIELTYGIKDVPGDRTTIDLTEDENQYS 859

Query: 1506 LTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVT 1565
            + NL P TEY VS+++  G   S       +T  D PR+L  V+ T  S+ + W      
Sbjct: 860  IGNLKPDTEYEVSLISRRGDMSSNPAKETFTTGLDAPRNLRRVSQTDNSITLEWRNGKAA 919

Query: 1566 VRYYRITYGETGGNSPVQEFTVPGSK---STATISGLKPGVDYTITVYAVTGRGDSPASS 1622
            +  YRI Y    G     E  VP S+   +  T++GL+PG +Y I V AV         S
Sbjct: 920  IDSYRIKYAPISGGDHA-EVDVPKSQQATTKTTLTGLRPGTEYGIGVSAV----KEDKES 974

Query: 1623 KPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPG-----PTK 1677
             P +IN  TE+D P  +QV++  + S+++ W    +    YR+  +   G       P  
Sbjct: 975  NPATINAATELDTPKDLQVSETAETSLTLLWKTPLAKFDRYRLNYSLPTGQWVGVQLPRN 1034

Query: 1678 TKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPL-VQTAVTNIDRPKGLAFTDVDV 1736
            T       T   + GL+P  EY V + A+    +S+P  V+ +       + L  T+V  
Sbjct: 1035 T-------TSYVLRGLEPGQEYNVLLTAEKGRHKSKPARVKASTEQAPELENLTVTEVGW 1087

Query: 1737 DSIKIAWESPQGQVSRY--RVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVV 1794
            D +++ W +       +  +V  ++  +    L     G     ++ GL+  + YTVS+ 
Sbjct: 1088 DGLRLNWTAADQAYEHFIIQVQEANKVEAARNL--TVPGSLRAVDIPGLKAATPYTVSIY 1145

Query: 1795 ALHDDMESQPLIGTQSTA-IPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKT 1853
             +     +  L    ST   P   ++   +V   +L   WT P      + ++V   +  
Sbjct: 1146 GVIQGYRTPVLSAEASTGETPNLGEVVVAEVGWDALKLNWTAPEGAYEYFFIQVQEADTV 1205

Query: 1854 GPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARV 1913
               + + +     S  + GL  AT Y +++  +    ++ P    V T E V       V
Sbjct: 1206 EAAQNLTVPGGLRSTDLPGLKAATHYTITIRGVTQDFSTTPLSVEVLT-EEVPDMGNLTV 1264

Query: 1914 TDATETTITISWRTKTETITGFQVDAVPANG-QTPIQRTIKPDVRSYTITGLQPGTDYKI 1972
            T+ +   + ++W T   T   F +    A+  +     T+   +RS  I GL+ GT Y +
Sbjct: 1265 TEVSWDALRLNWTTPDGTYDQFTIQVQEADQVEEAHNLTVPGSLRSMEIPGLRAGTPYTV 1324

Query: 1973 YLYTLNDNARSSPVVIDASTAIDAP--SNLRFLATTPNSLLVSWQPPRARITGYIIKYEK 2030
             L+       + P+ ++  T  D P   +L       + L ++W         ++I+ ++
Sbjct: 1325 TLHGEVRGHSTRPLAVEVVTE-DLPQLGDLAVSEVGWDGLRLNWTAADNAYEHFVIQVQE 1383

Query: 2031 PGSPPREVVPRPRPGVTEAT-ITGLEPGTEY--TIY---------VIALKNNQKSEPLIG 2078
              +          PG   A  I GLE  T Y  +IY         V++ + +   EP IG
Sbjct: 1384 V-NKVEAAQNLTLPGSLRAVDIPGLEAATPYRVSIYGVIRGYRTPVLSAEASTAKEPEIG 1442

Query: 2079 RKKTVQKTPFVTHPGYDTGNGIQLPGTSG--QQPSVGQQMIFEEHGFRRTT-----PPTT 2131
                   TP   +  +   +GI    T        + + + +   G  RT      PP+T
Sbjct: 1443 NLNVSDITPESFNLSWMATDGIFETFTIEIIDSNRLLETVEYNISGAERTAHISGLPPST 1502

Query: 2132 ATPIRHRPRPYPPNVGQEALSQT----------------------TISWAPFQDT-SEYI 2168
               +        P++  + +S T                      T+SW   ++    ++
Sbjct: 1503 DFIV--YLSGLAPSIRTKTISATATTEALPLLENLTISDINPYGFTVSWMASENAFDSFL 1560

Query: 2169 ISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEAL-KDQQRHKVREEVVT--- 2224
            ++    G   +P +F + GT     L GL  G  Y ++V    +  Q   +R E+VT   
Sbjct: 1561 VTVVDSGKLLDPQEFTLSGTQRKLELRGLITGIGYEVMVSGFTQGHQTKPLRAEIVTEAE 1620

Query: 2225 -------VGNSVNEG--LNQPTDDSCFDPYTV 2247
                   V ++  +G  L+   D+  FD + +
Sbjct: 1621 PEVDNLLVSDATPDGFRLSWTADEGVFDNFVL 1652



 Score =  208 bits (530), Expect = 5e-53
 Identities = 186/811 (22%), Positives = 334/811 (41%), Gaps = 56/811 (6%)

Query: 1443 GRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRN 1502
            G   + +  P  +  +++T  +  + W      +T Y + + P H  G   + RVP  + 
Sbjct: 617  GEDCSEVSPPKDLVVTEVTEETVNLAW-DNEMRVTEYLVVYTPTHEGGLEMQFRVPGDQT 675

Query: 1503 SITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAP 1562
            S  +  L PG EY + + A+   ++S  +  + +T    P  L+  +   TS+ + WD  
Sbjct: 676  STIIQELEPGVEYFIRVFAILENKKSIPVSARVATYLPAPEGLKFKSIKETSVEVEWDPL 735

Query: 1563 AVTVRYYRITYGETGGNSPVQ-EFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPAS 1621
             +    + I +         +   ++   +++   +GL PG +Y I+++ V      P  
Sbjct: 736  DIAFETWEIIFRNMNKEDEGEITKSLRRPETSYRQTGLAPGQEYEISLHIVKNNTRGPGL 795

Query: 1622 SKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTA 1681
             +  +    T +D PSQ++V DV D +  + W    + + G  +T   K+ PG   T   
Sbjct: 796  KRVTT----TRLDAPSQIEVKDVTDTTALITWFKPLAEIDGIELTYGIKDVPGDRTTIDL 851

Query: 1682 GPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKI 1741
              D+ + +I  L+P  EY VS+ ++     S P  +T  T +D P+ L       +SI +
Sbjct: 852  TEDENQYSIGNLKPDTEYEVSLISRRGDMSSNPAKETFTTGLDAPRNLRRVSQTDNSITL 911

Query: 1742 AWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAE--LQGLRPGSEYTVSVVALHDD 1799
             W + +  +  YR+ Y+    G H     P  ++ T +  L GLRPG+EY + V A+ +D
Sbjct: 912  EWRNGKAAIDSYRIKYAPISGGDHAEVDVPKSQQATTKTTLTGLRPGTEYGIGVSAVKED 971

Query: 1800 MESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEI 1859
             ES P     +T +  P DL+ ++   TSL+  W  P  +   YR+  +    TG    +
Sbjct: 972  KESNPATINAATELDTPKDLQVSETAETSLTLLWKTPLAKFDRYRLNYS--LPTGQWVGV 1029

Query: 1860 NLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATET 1919
             L  +++S V+ GL    +Y V + A K    S+PA+ V  + E         VT+    
Sbjct: 1030 QLPRNTTSYVLRGLEPGQEYNVLLTAEKGRHKSKPAR-VKASTEQAPELENLTVTEVGWD 1088

Query: 1920 TITISWRTKTETITGFQVDAVPANG-QTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLN 1978
             + ++W    +    F +    AN  +     T+   +R+  I GL+  T Y + +Y + 
Sbjct: 1089 GLRLNWTAADQAYEHFIIQVQEANKVEAARNLTVPGSLRAVDIPGLKAATPYTVSIYGVI 1148

Query: 1979 DNARSSPVVIDASTAIDAPSNLRFLATTP---NSLLVSWQPPRARITGYIIKYEKPGSPP 2035
               R+  +  +AST  + P NL  +       ++L ++W  P      + I+ ++  +  
Sbjct: 1149 QGYRTPVLSAEASTG-ETP-NLGEVVVAEVGWDALKLNWTAPEGAYEYFFIQVQEADTVE 1206

Query: 2036 REVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQKTPF----VTH 2091
                     G+    + GL+  T YTI +  +  +  + PL     T +        VT 
Sbjct: 1207 AAQNLTVPGGLRSTDLPGLKAATHYTITIRGVTQDFSTTPLSVEVLTEEVPDMGNLTVTE 1266

Query: 2092 PGYDT--GNGIQLPGTSGQQPSVGQQ--MIFEEH--------------GFRRTTPPTTAT 2133
              +D    N     GT  Q     Q+   + E H              G R  TP T   
Sbjct: 1267 VSWDALRLNWTTPDGTYDQFTIQVQEADQVEEAHNLTVPGSLRSMEIPGLRAGTPYTVTL 1326

Query: 2134 --PIR-HRPRPYP--------PNVGQEALSQT-----TISWAPFQDTSE-YIISCHPVGT 2176
               +R H  RP          P +G  A+S+       ++W    +  E ++I    V  
Sbjct: 1327 HGEVRGHSTRPLAVEVVTEDLPQLGDLAVSEVGWDGLRLNWTAADNAYEHFVIQVQEVNK 1386

Query: 2177 DEEPLQFRVPGTSTSATLTGLTRGATYNIIV 2207
             E      +PG+  +  + GL     Y + +
Sbjct: 1387 VEAAQNLTLPGSLRAVDIPGLEAATPYRVSI 1417



 Score =  182 bits (463), Expect = 3e-45
 Identities = 151/558 (27%), Positives = 250/558 (44%), Gaps = 55/558 (9%)

Query: 1721 TNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAEL 1780
            + +  PK L  T+V  +++ +AW++   +V+ Y V Y+   +G  E+     G++ +  +
Sbjct: 621  SEVSPPKDLVVTEVTEETVNLAWDNEM-RVTEYLVVYTPTHEGGLEMQFRVPGDQTSTII 679

Query: 1781 QGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQL 1840
            Q L PG EY + V A+ ++ +S P+    +T +PAP  LKF  +  TS+  +W P ++  
Sbjct: 680  QELEPGVEYFIRVFAILENKKSIPVSARVATYLPAPEGLKFKSIKETSVEVEWDPLDIAF 739

Query: 1841 TGYRV--RVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGV 1898
              + +  R   KE  G + +    P++S    +GL    +YE+S++ +K+       + V
Sbjct: 740  ETWEIIFRNMNKEDEGEITKSLRRPETS-YRQTGLAPGQEYEISLHIVKNNTRGPGLKRV 798

Query: 1899 VTTLENVSPPRRARVTDATETTITISWRTKTETITGFQ----VDAVPANGQTPIQRTIKP 1954
             TT   +  P +  V D T+TT  I+W      I G +    +  VP + +T I  T   
Sbjct: 799  TTT--RLDAPSQIEVKDVTDTTALITWFKPLAEIDGIELTYGIKDVPGD-RTTIDLT--E 853

Query: 1955 DVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSW 2014
            D   Y+I  L+P T+Y++ L +   +  S+P     +T +DAP NLR ++ T NS+ + W
Sbjct: 854  DENQYSIGNLKPDTEYEVSLISRRGDMSSNPAKETFTTGLDAPRNLRRVSQTDNSITLEW 913

Query: 2015 QPPRARITGYIIKYEK-PGSPPREV-VPRPRPGVTEATITGLEPGTEYTIYVIALKNNQK 2072
            +  +A I  Y IKY    G    EV VP+ +   T+ T+TGL PGTEY I V A+K +++
Sbjct: 914  RNGKAAIDSYRIKYAPISGGDHAEVDVPKSQQATTKTTLTGLRPGTEYGIGVSAVKEDKE 973

Query: 2073 SEPL-------IGRKKTVQ-------------KTPFVTHPGY------DTGN--GIQLPG 2104
            S P        +   K +Q             KTP      Y       TG   G+QLP 
Sbjct: 974  SNPATINAATELDTPKDLQVSETAETSLTLLWKTPLAKFDRYRLNYSLPTGQWVGVQLPR 1033

Query: 2105 TS------GQQPSVGQQ---MIFEEHGFRRTTPPTTATPIRHRPRPYPPNVGQEALSQTT 2155
             +      G +P  GQ+   ++  E G  ++ P          P      V +       
Sbjct: 1034 NTTSYVLRGLEP--GQEYNVLLTAEKGRHKSKPARVKASTEQAPELENLTVTEVGWDGLR 1091

Query: 2156 ISW-APFQDTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQ 2214
            ++W A  Q    +II        E      VPG+  +  + GL     Y + +  +    
Sbjct: 1092 LNWTAADQAYEHFIIQVQEANKVEAARNLTVPGSLRAVDIPGLKAATPYTVSIYGVIQGY 1151

Query: 2215 RHKVREEVVTVGNSVNEG 2232
            R  V     + G + N G
Sbjct: 1152 RTPVLSAEASTGETPNLG 1169



 Score =  152 bits (385), Expect = 3e-36
 Identities = 152/694 (21%), Positives = 275/694 (39%), Gaps = 47/694 (6%)

Query: 628  IQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQY 687
            + W A   ++   ++++ +  N V   +  T+PG L +  I GL+    Y   +  + + 
Sbjct: 1365 LNWTAADNAY-EHFVIQVQEVNKVEAAQNLTLPGSLRAVDIPGLEAATPYRVSIYGVIR- 1422

Query: 688  GHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTV 747
            G++             TPV S   +    P       + +V++IT  SF +SW++     
Sbjct: 1423 GYR-------------TPVLSAEASTAKEP----EIGNLNVSDITPESFNLSWMATDGIF 1465

Query: 748  SGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQ 807
              F +E   S    E    ++     + +I  L P   +IV +  ++       I +T+ 
Sbjct: 1466 ETFTIEIIDSNRLLETVEYNISGAERTAHISGLPPSTDFIVYLSGLAPSIRTKTISATAT 1525

Query: 808  TTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEG-SSTELNLPETANSVT 866
            T A     + T+  ++     V W   +     + +    S +     E  L  T   + 
Sbjct: 1526 TEALPLLENLTISDINPYGFTVSWMASENAFDSFLVTVVDSGKLLDPQEFTLSGTQRKLE 1585

Query: 867  LSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIM 926
            L  L  G+ Y + +    +  ++ P+  +  T   P  D      +L   + T     + 
Sbjct: 1586 LRGLITGIGYEVMVSGFTQGHQTKPLRAEIVTEAEPEVD------NLLVSDATPDGFRLS 1639

Query: 927  WTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRES 986
            WT  E     + + +       E  +   ++     ++TGL     Y  +++ +S GR S
Sbjct: 1640 WTADEGVFDNFVLKIRDTKKQSEPLEITLLAPERTRDITGLREATEYEIELYGISKGRRS 1699

Query: 987  KPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGP 1046
            + ++A  TT + +P  + F + T+++  V W  P AQ+  +R+T      G P    V  
Sbjct: 1700 QTVSAIATTAMGSPKEVIFSDITENSATVSWRAPTAQVESFRITYVPITGGTPSMVTVDG 1759

Query: 1047 SVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVIT 1106
            + ++  L  L P  EY VS++A+KG +ES   +G FTT   G S       +T++  +  
Sbjct: 1760 TKTQTRLVKLIPGVEYLVSIIAMKGFEESEPVSGSFTTALDGPS-GLVTANITDSEALAR 1818

Query: 1107 WTPAPRI--GFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDA 1164
            W PA      + +     +  E  R V+ ++    ++ L P  EY   I     G ++ +
Sbjct: 1819 WQPAIATVDSYVISYTGEKVPEITRTVSGNTVEYALTDLEPATEYTLRI-FAEKGPQKSS 1877

Query: 1165 PIVNKVVTPLSPPTNL-HLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEE 1223
             I  K  T L  P +L   E   +T +LT  W R     +TGY +     +   G   E 
Sbjct: 1878 TITAKFTTDLDSPRDLTATEVQSETALLT--W-RPPRASVTGYLLVYESVD---GTVKEV 1931

Query: 1224 VVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPEVPQLTDLSFVDITDSSI 1283
            +V  D +S +  +LSP   Y   +  +       P+   +I  +     L +    D S 
Sbjct: 1932 IVGPDTTSYSLADLSPSTHYTAKIQALNG-----PLRSNMIQTIFTTIGLLYPFPKDCSQ 1986

Query: 1284 GLRWTPLNSSTIIGYRITVVAAGEGIPIFEDFVD 1317
             +    LN  T  G   T+   G+     E F D
Sbjct: 1987 AM----LNGDTTSGL-YTIYLNGDKAEALEVFCD 2015


>gi|157384973 tenascin R [Homo sapiens]
          Length = 1358

 Score =  329 bits (844), Expect = 2e-89
 Identities = 237/807 (29%), Positives = 374/807 (46%), Gaps = 32/807 (3%)

Query: 1272 DLSFVDITDSSIGLRWTPLNSST--IIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLE 1329
            DL    I+D SI L W    + T  +I Y+ T +   +     +  V       T+T LE
Sbjct: 331  DLRVAGISDRSIELEWDGPMAVTEYVISYQPTALGGLQ----LQQRVPGDWSGVTITELE 386

Query: 1330 PGIDYDISVITLINGGESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNF 1389
            PG+ Y+ISV  +I+   S P T    T +  P  L+F  I   T+ V W P  S     +
Sbjct: 387  PGLTYNISVYAVISNILSLPITAKVATHLSTPQGLQFKTITETTVEVQWEPF-SFSFDGW 445

Query: 1390 LVRYSPVKNEEDVAELSISPSD-NAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTG 1448
             + + P  NE  V  ++  PSD  +   T L PG EY+V+V ++ EQ  S P      T 
Sbjct: 446  EISFIPKNNEGGV--IAQVPSDVTSFNQTGLKPGEEYIVNVVALKEQARSPPTSASVSTV 503

Query: 1449 LDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTN 1508
            +D PT I   D++     V WI PRA +    +++      G     R+    +  ++  
Sbjct: 504  IDGPTQILVRDVSDTVAFVEWIPPRAKVDFILLKYGLVGGEGGRTTFRLQPPLSQYSVQA 563

Query: 1509 LTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRY 1568
            L PG+ Y VS+ A+ G  ES     Q +T  D P++L V + T TSL + WD     V+ 
Sbjct: 564  LRPGSRYEVSVSAVRGTNESDSATTQFTTEIDAPKNLRVGSRTATSLDLEWDNSEAEVQE 623

Query: 1569 YRITYGETGGNSPVQEFTVP---GSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPI 1625
            Y++ Y    G     E  VP   G  + AT++ L PG +Y + + AV     +   S P 
Sbjct: 624  YKVVYSTLAGEQ-YHEVLVPRGIGPTTRATLTDLVPGTEYGVGISAVM----NSQQSVPA 678

Query: 1626 SINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQ 1685
            ++N RTE+D P  + VT   + SIS+ W  +S P+  YR+T TP +G       T   D+
Sbjct: 679  TMNARTELDSPRDLMVTASSETSISLIWTKASGPIDHYRITFTPSSGIA--SEVTVPKDR 736

Query: 1686 TEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWES 1745
            T  T+  L+P  EY++SV A+    +S      A T       L F+ V   S+ I W  
Sbjct: 737  TSYTLTDLEPGAEYIISVTAERGRQQSLESTVDAFTGFRPISHLHFSHVTSSSVNITWSD 796

Query: 1746 PQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPL 1805
            P     R  + YS  ++    +  + D  +  A L GL+P +EY V++VA+H  + S+P+
Sbjct: 797  PSPPADRLILNYSPRDEEEEMMEVSLDATKRHAVLMGLQPATEYIVNLVAVHGTVTSEPI 856

Query: 1806 IGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDS 1865
            +G+ +T I  P D+  + VT  S+   W+PP      YRV   P +  G +    +    
Sbjct: 857  VGSITTGIDPPKDITISNVTKDSVMVSWSPPVASFDYYRVSYRPTQ-VGRLDSSVVPNTV 915

Query: 1866 SSVVVSGLMVATKYEVSVYALKDTLTS-RPAQGVVTTLENVSPPRRARVTDATETTITIS 1924
            +   ++ L  AT+YE+S+ +++    S R    V T ++N   P     T+ T T   + 
Sbjct: 916  TEFTITRLNPATEYEISLNSVRGREESERICTLVHTAMDN---PVDLIATNITPTEALLQ 972

Query: 1925 WRTKTETITGFQV--DAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNAR 1982
            W+     +  + +        G+T +   +  + R   +  L P T Y   +Y  N    
Sbjct: 973  WKAPVGEVENYVIVLTHFAVAGETILVDGVSEEFR---LVDLLPSTHYTATMYATNGPLT 1029

Query: 1983 SSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRP 2042
            S  +  + ST +D P+NL     T  S L+SWQPPRA I  Y++ Y+      +E++   
Sbjct: 1030 SGTISTNFSTLLDPPANLTASEVTRQSALISWQPPRAEIENYVLTYKSTDGSRKELIVDA 1089

Query: 2043 RPGVTEATITGLEPGTEYTIYVIALKN 2069
                T   + GL   T+YT+ + A ++
Sbjct: 1090 ED--TWIRLEGLLENTDYTVLLQAAQD 1114



 Score =  315 bits (807), Expect = 3e-85
 Identities = 243/828 (29%), Positives = 372/828 (44%), Gaps = 30/828 (3%)

Query: 902  PRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTF 961
            P    V  P DL+   ++D  + + W  P  AVT Y +   P  L G   Q+      + 
Sbjct: 321  PDCSAVAPPEDLRVAGISDRSIELEWDGP-MAVTEYVISYQPTALGGLQLQQRVPGDWSG 379

Query: 962  AEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPR 1021
              +T L PG+TY   V+AV     S P+TA+  T L  P  LQF   T++TV V+W P  
Sbjct: 380  VTITELEPGLTYNISVYAVISNILSLPITAKVATHLSTPQGLQFKTITETTVEVQWEPFS 439

Query: 1022 AQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGV 1081
                G+ ++             V   V+ +    L+P  EY V++VA+K    SP  +  
Sbjct: 440  FSFDGWEISFIPKNNEGGVIAQVPSDVTSFNQTGLKPGEEYIVNVVALKEQARSPPTSAS 499

Query: 1082 FTTLQPGSSIPPYNTEVTETTIVITWTPAPR-----IGFKLGVRPSQGGEAPREVTSDSG 1136
             +T+  G +      +V++T   + W P PR     I  K G+   +GG     +     
Sbjct: 500  VSTVIDGPT-QILVRDVSDTVAFVEWIP-PRAKVDFILLKYGLVGGEGGRTTFRLQPPLS 557

Query: 1137 SIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWE 1196
               V  L PG  Y  ++  +R   E D+    +  T +  P NL + +   T  L + W+
Sbjct: 558  QYSVQALRPGSRYEVSVSAVRGTNESDS-ATTQFTTEIDAPKNLRVGSRTATS-LDLEWD 615

Query: 1197 RSTTPDITGYRITTTPTNGQQGNS-LEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKE 1255
             S   ++  Y++  +   G+Q +  L        +  T  +L PG EY V +  V + ++
Sbjct: 616  NSEA-EVQEYKVVYSTLAGEQYHEVLVPRGIGPTTRATLTDLVPGTEYGVGISAVMNSQQ 674

Query: 1256 SVPISDTIIPEVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIFEDF 1315
            SVP +     E+    DL     +++SI L WT   S  I  YRIT   +  GI   E  
Sbjct: 675  SVPATMNARTELDSPRDLMVTASSETSISLIWTKA-SGPIDHYRITFTPS-SGI-ASEVT 731

Query: 1316 VDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAVPPPTDLRFTNIGPDTMR 1375
            V      YT+T LEPG +Y ISV       +S  +T+   T   P + L F+++   ++ 
Sbjct: 732  VPKDRTSYTLTDLEPGAEYIISVTAERGRQQSLESTVDAFTGFRPISHLHFSHVTSSSVN 791

Query: 1376 VTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQ 1435
            +TW+  PS      ++ YSP   EE++ E+S+  +    VL  L P TEY+V++ +V+  
Sbjct: 792  ITWS-DPSPPADRLILNYSPRDEEEEMMEVSLDATKRHAVLMGLQPATEYIVNLVAVHGT 850

Query: 1436 HESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPRED 1495
              S P+ G   TG+D P  I  S++T +S  V W  P A+   YR+ + P    GR    
Sbjct: 851  VTSEPIVGSITTGIDPPKDITISNVTKDSVMVSWSPPVASFDYYRVSYRPTQV-GRLDSS 909

Query: 1496 RVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSL 1555
             VP++    T+T L P TEY +S+ ++ GREES  +     T  D P DL     TPT  
Sbjct: 910  VVPNTVTEFTITRLNPATEYEISLNSVRGREESERICTLVHTAMDNPVDLIATNITPTEA 969

Query: 1556 LISWDAPAVTVRYYRI--TYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVT 1613
            L+ W AP   V  Y I  T+    G    +   V G      +  L P   YT T+YA  
Sbjct: 970  LLQWKAPVGEVENYVIVLTHFAVAG----ETILVDGVSEEFRLVDLLPSTHYTATMYATN 1025

Query: 1614 GRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGP 1673
            G    P +S  IS N+ T +D P+ +  ++V   S  + W P  + +  Y    T K+  
Sbjct: 1026 G----PLTSGTISTNFSTLLDPPANLTASEVTRQSALISWQPPRAEIENY--VLTYKSTD 1079

Query: 1674 GPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVT 1721
            G  K      + T + +EGL    +Y V + A   +  S  +  TA T
Sbjct: 1080 GSRKELIVDAEDTWIRLEGLLENTDYTVLLQAAQDTTWSS-ITSTAFT 1126



 Score =  308 bits (788), Expect = 5e-83
 Identities = 243/852 (28%), Positives = 391/852 (45%), Gaps = 56/852 (6%)

Query: 783  GRKYIVNVYQISEDGEQSLILSTSQTTAPD----APP-DPTVDQVDDTSIVVRWSRPQAP 837
            G++  +N        E+ L +       PD    APP D  V  + D SI + W  P A 
Sbjct: 293  GQRQCLNACSGRGQCEEGLCVCEEGYQGPDCSAVAPPEDLRVAGISDRSIELEWDGPMA- 351

Query: 838  ITGYRIVYSPSVEGS-STELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQ 896
            +T Y I Y P+  G    +  +P   + VT+++L+PG+ YNI++YAV  N  S P+  + 
Sbjct: 352  VTEYVISYQPTALGGLQLQQRVPGDWSGVTITELEPGLTYNISVYAVISNILSLPITAKV 411

Query: 897  ETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPI 956
             T        + +P+ LQF  +T+  V + W P   +  G+ +  IP N  G    ++P 
Sbjct: 412  AT-------HLSTPQGLQFKTITETTVEVQWEPFSFSFDGWEISFIPKNNEGGVIAQVPS 464

Query: 957  SRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVR 1016
               +F + TGL PG  Y   V A+     S P +A  +T +D PT +   + +D+   V 
Sbjct: 465  DVTSFNQ-TGLKPGEEYIVNVVALKEQARSPPTSASVSTVIDGPTQILVRDVSDTVAFVE 523

Query: 1017 WTPPRAQITGYRLTVGLT-RRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQES 1075
            W PPRA++    L  GL    G    + + P +S+Y ++ L+P S Y VS+ A++G  ES
Sbjct: 524  WIPPRAKVDFILLKYGLVGGEGGRTTFRLQPPLSQYSVQALRPGSRYEVSVSAVRGTNES 583

Query: 1076 PKATGVFTTLQPGSSIPPYNTEV---TETTIVITW--TPAPRIGFKLGVRPSQGGEAPRE 1130
              AT  FTT        P N  V   T T++ + W  + A    +K+ V  +  GE   E
Sbjct: 584  DSATTQFTT----EIDAPKNLRVGSRTATSLDLEWDNSEAEVQEYKV-VYSTLAGEQYHE 638

Query: 1131 VTSDSG-----SIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEAN 1185
            V    G        ++ L PG EY   I  + + Q+   P      T L  P +L + A+
Sbjct: 639  VLVPRGIGPTTRATLTDLVPGTEYGVGISAVMNSQQ-SVPATMNARTELDSPRDLMVTAS 697

Query: 1186 PDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNV 1245
             +T + ++ W +++ P I  YRIT TP++   G + E  V  D++S T  +L PG EY +
Sbjct: 698  SETSI-SLIWTKASGP-IDHYRITFTPSS---GIASEVTVPKDRTSYTLTDLEPGAEYII 752

Query: 1246 SVYTVKDDKESVPISDTIIPEVPQLTDLSFVDITDSSIGLRW---TPLNSSTIIGYRITV 1302
            SV   +  ++S+  +         ++ L F  +T SS+ + W   +P     I+ Y    
Sbjct: 753  SVTAERGRQQSLESTVDAFTGFRPISHLHFSHVTSSSVNITWSDPSPPADRLILNYS--- 809

Query: 1303 VAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAVPPPT 1362
                E   + E  +D++  +  + GL+P  +Y ++++ +     S P   +  T + PP 
Sbjct: 810  -PRDEEEEMMEVSLDATKRHAVLMGLQPATEYIVNLVAVHGTVTSEPIVGSITTGIDPPK 868

Query: 1363 DLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAV---VLTNL 1419
            D+  +N+  D++ V+W+PP +     + V Y P +    V  L  S   N V    +T L
Sbjct: 869  DITISNVTKDSVMVSWSPPVA-SFDYYRVSYRPTQ----VGRLDSSVVPNTVTEFTITRL 923

Query: 1420 LPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGY 1479
             P TEY +S++SV  + ES  +     T +D+P  +  ++IT     + W AP   +  Y
Sbjct: 924  NPATEYEISLNSVRGREESERICTLVHTAMDNPVDLIATNITPTEALLQWKAPVGEVENY 983

Query: 1480 RIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVS 1539
             I     HF+       V        L +L P T Y  ++ A NG   S  +    ST+ 
Sbjct: 984  VI--VLTHFAVAGETILVDGVSEEFRLVDLLPSTHYTATMYATNGPLTSGTISTNFSTLL 1041

Query: 1540 DVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGL 1599
            D P +L     T  S LISW  P   +  Y +TY  T G+   +E  V    +   + GL
Sbjct: 1042 DPPANLTASEVTRQSALISWQPPRAEIENYVLTYKSTDGSR--KELIVDAEDTWIRLEGL 1099

Query: 1600 KPGVDYTITVYA 1611
                DYT+ + A
Sbjct: 1100 LENTDYTVLLQA 1111



 Score =  265 bits (676), Expect = 5e-70
 Identities = 216/817 (26%), Positives = 357/817 (43%), Gaps = 27/817 (3%)

Query: 1098 VTETTIVITWT-PAPRIGFKLGVRPSQGG--EAPREVTSDSGSIVVSGLTPGVEYVYTIQ 1154
            +++ +I + W  P     + +  +P+  G  +  + V  D   + ++ L PG+ Y  ++ 
Sbjct: 337  ISDRSIELEWDGPMAVTEYVISYQPTALGGLQLQQRVPGDWSGVTITELEPGLTYNISVY 396

Query: 1155 VLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTN 1214
             +        PI  KV T LS P  L  +   +T V  V WE  +     G+ I+  P N
Sbjct: 397  AVISNI-LSLPITAKVATHLSTPQGLQFKTITETTV-EVQWEPFSF-SFDGWEISFIPKN 453

Query: 1215 GQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPEVPQLTDLS 1274
             + G   +  V +D +S     L PG EY V+V  +K+   S P S ++   +   T + 
Sbjct: 454  NEGGVIAQ--VPSDVTSFNQTGLKPGEEYIVNVVALKEQARSPPTSASVSTVIDGPTQIL 511

Query: 1275 FVDITDSSIGLRWTPLNSST-IIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGID 1333
              D++D+   + W P  +    I  +  +V    G   F   +   +  Y+V  L PG  
Sbjct: 512  VRDVSDTVAFVEWIPPRAKVDFILLKYGLVGGEGGRTTFR--LQPPLSQYSVQALRPGSR 569

Query: 1334 YDISVITLINGGESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRY 1393
            Y++SV  +    ES   T    T +  P +LR  +    ++ + W    + ++  + V Y
Sbjct: 570  YEVSVSAVRGTNESDSATTQFTTEIDAPKNLRVGSRTATSLDLEWDNSEA-EVQEYKVVY 628

Query: 1394 SPVKNE---EDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLD 1450
            S +  E   E +    I P+  A  LT+L+PGTEY V +S+V    +S P     +T LD
Sbjct: 629  STLAGEQYHEVLVPRGIGPTTRAT-LTDLVPGTEYGVGISAVMNSQQSVPATMNARTELD 687

Query: 1451 SPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLT 1510
            SP  +  +  +  S ++ W      I  YRI   P   SG   E  VP  R S TLT+L 
Sbjct: 688  SPRDLMVTASSETSISLIWTKASGPIDHYRITFTPS--SGIASEVTVPKDRTSYTLTDLE 745

Query: 1511 PGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYR 1570
            PG EY++S+ A  GR++S        T       L     T +S+ I+W  P+       
Sbjct: 746  PGAEYIISVTAERGRQQSLESTVDAFTGFRPISHLHFSHVTSSSVNITWSDPSPPADRLI 805

Query: 1571 ITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYR 1630
            + Y        + E ++  +K  A + GL+P  +Y + + AV G      +S+PI  +  
Sbjct: 806  LNYSPRDEEEEMMEVSLDATKRHAVLMGLQPATEYIVNLVAVHGT----VTSEPIVGSIT 861

Query: 1631 TEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTI 1690
            T ID P  + +++V  +S+ V W P  +    YRV+  P    G   +       TE TI
Sbjct: 862  TGIDPPKDITISNVTKDSVMVSWSPPVASFDYYRVSYRPTQ-VGRLDSSVVPNTVTEFTI 920

Query: 1691 EGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQV 1750
              L P  EY +S+ +     ES+ +     T +D P  L  T++      + W++P G+V
Sbjct: 921  TRLNPATEYEISLNSVRGREESERICTLVHTAMDNPVDLIATNITPTEALLQWKAPVGEV 980

Query: 1751 SRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQS 1810
              Y +  +        +    DG  +   L  L P + YT ++ A +  + S  +    S
Sbjct: 981  ENYVIVLTHFAVAGETILV--DGVSEEFRLVDLLPSTHYTATMYATNGPLTSGTISTNFS 1038

Query: 1811 TAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVV 1870
            T +  P +L  ++VT  S    W PP  ++  Y +  T K   G  KE+ +  + + + +
Sbjct: 1039 TLLDPPANLTASEVTRQSALISWQPPRAEIENYVL--TYKSTDGSRKELIVDAEDTWIRL 1096

Query: 1871 SGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSP 1907
             GL+  T Y V + A +DT  S       TT   V P
Sbjct: 1097 EGLLENTDYTVLLQAAQDTTWSSITSTAFTTGGRVFP 1133



 Score =  244 bits (622), Expect = 1e-63
 Identities = 176/651 (27%), Positives = 293/651 (45%), Gaps = 18/651 (2%)

Query: 1442 RGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSR 1501
            +G   + +  P  +  + I+  S  + W  P A +T Y I + P    G   + RVP   
Sbjct: 319  QGPDCSAVAPPEDLRVAGISDRSIELEWDGPMA-VTEYVISYQPTALGGLQLQQRVPGDW 377

Query: 1502 NSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDA 1561
            + +T+T L PG  Y +S+ A+     S  +  + +T    P+ L+    T T++ + W+ 
Sbjct: 378  SGVTITELEPGLTYNISVYAVISNILSLPITAKVATHLSTPQGLQFKTITETTVEVQWEP 437

Query: 1562 PAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPAS 1621
             + +   + I++        V    VP   ++   +GLKPG +Y + V A+  +  SP +
Sbjct: 438  FSFSFDGWEISFIPKNNEGGVIA-QVPSDVTSFNQTGLKPGEEYIVNVVALKEQARSPPT 496

Query: 1622 SKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTA 1681
            S  +S    T ID P+Q+ V DV D    V+W+P  + V    +      G G   T   
Sbjct: 497  SASVS----TVIDGPTQILVRDVSDTVAFVEWIPPRAKVDFILLKYGLVGGEGGRTTFRL 552

Query: 1682 GPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKI 1741
             P  ++ +++ L+P   Y VSV A   + ES        T ID PK L        S+ +
Sbjct: 553  QPPLSQYSVQALRPGSRYEVSVSAVRGTNESDSATTQFTTEIDAPKNLRVGSRTATSLDL 612

Query: 1742 AWESPQGQVSRYRVTYSS-PEDGIHE-LFPAPDGEEDTAELQGLRPGSEYTVSVVALHDD 1799
             W++ + +V  Y+V YS+   +  HE L P   G    A L  L PG+EY V + A+ + 
Sbjct: 613  EWDNSEAEVQEYKVVYSTLAGEQYHEVLVPRGIGPTTRATLTDLVPGTEYGVGISAVMNS 672

Query: 1800 MESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEI 1859
             +S P      T + +P DL  T  + TS+S  WT  +  +  YR+  TP   +G   E+
Sbjct: 673  QQSVPATMNARTELDSPRDLMVTASSETSISLIWTKASGPIDHYRITFTPS--SGIASEV 730

Query: 1860 NLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATET 1919
             +  D +S  ++ L    +Y +SV A +    S   +  V       P      +  T +
Sbjct: 731  TVPKDRTSYTLTDLEPGAEYIISVTAERGRQQS--LESTVDAFTGFRPISHLHFSHVTSS 788

Query: 1920 TITISWRTKTETITGFQVDAVPANGQTPIQR-TIKPDVRSYTITGLQPGTDYKIYLYTLN 1978
            ++ I+W   +       ++  P + +  +   ++    R   + GLQP T+Y + L  ++
Sbjct: 789  SVNITWSDPSPPADRLILNYSPRDEEEEMMEVSLDATKRHAVLMGLQPATEYIVNLVAVH 848

Query: 1979 DNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYE--KPGSPPR 2036
                S P+V   +T ID P ++     T +S++VSW PP A    Y + Y   + G    
Sbjct: 849  GTVTSEPIVGSITTGIDPPKDITISNVTKDSVMVSWSPPVASFDYYRVSYRPTQVGRLDS 908

Query: 2037 EVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQKTP 2087
             VVP     VTE TIT L P TEY I + +++  ++SE +     T    P
Sbjct: 909  SVVPNT---VTEFTITRLNPATEYEISLNSVRGREESERICTLVHTAMDNP 956



 Score =  237 bits (604), Expect = 1e-61
 Identities = 228/901 (25%), Positives = 383/901 (42%), Gaps = 108/901 (11%)

Query: 628  IQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQY 687
            ++W+ P    +++Y++ ++P    G   +  +PG  +  TI  L+PG+ Y          
Sbjct: 344  LEWDGPMA--VTEYVISYQPTALGGLQLQQRVPGDWSGVTITELEPGLTY---------- 391

Query: 688  GHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTV 747
                ++ +   +   S P+T+   T  +TP      T      IT ++  V W   S + 
Sbjct: 392  ---NISVYAVISNILSLPITAKVATHLSTPQGLQFKT------ITETTVEVQWEPFSFSF 442

Query: 748  SGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQ 807
             G+ + + + +  +      +PS  TS N   L PG +YIVNV  + E   +S   S S 
Sbjct: 443  DGWEISF-IPKNNEGGVIAQVPSDVTSFNQTGLKPGEEYIVNVVALKEQA-RSPPTSASV 500

Query: 808  TTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYS-PSVEGSSTELNLPETANSVT 866
            +T  D P    V  V DT   V W  P+A +    + Y     EG  T   L    +  +
Sbjct: 501  STVIDGPTQILVRDVSDTVAFVEWIPPRAKVDFILLKYGLVGGEGGRTTFRLQPPLSQYS 560

Query: 867  LSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIM 926
            +  L+PG +Y +++ AV    ES     Q  T        + +P++L+    T   + + 
Sbjct: 561  VQALRPGSRYEVSVSAVRGTNESDSATTQFTT-------EIDAPKNLRVGSRTATSLDLE 613

Query: 927  WTPPESAVTGYRVDVIPVNLPGEHGQRLPISR----NTFAEVTGLSPGVTYYFKVFAVSH 982
            W   E+ V  Y+  V+   L GE    + + R     T A +T L PG  Y   + AV +
Sbjct: 614  WDNSEAEVQEYK--VVYSTLAGEQYHEVLVPRGIGPTTRATLTDLVPGTEYGVGISAVMN 671

Query: 983  GRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQY 1042
             ++S P T    T+LD+P +L     +++++ + WT     I  YR+T      G   + 
Sbjct: 672  SQQSVPATMNARTELDSPRDLMVTASSETSISLIWTKASGPIDHYRITF-TPSSGIASEV 730

Query: 1043 NVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKAT-GVFTTLQPGSSIPPYNTEVTET 1101
             V    + Y L +L+P +EY +S+ A +G Q+S ++T   FT  +P S +  + + VT +
Sbjct: 731  TVPKDRTSYTLTDLEPGAEYIISVTAERGRQQSLESTVDAFTGFRPISHL--HFSHVTSS 788

Query: 1102 TIVITWT----PAPRIGFKLGVRPSQGGEAPREVTSDSGS--IVVSGLTPGVEYVYTIQV 1155
            ++ ITW+    PA R+   L   P    E   EV+ D+     V+ GL P  EY+  + V
Sbjct: 789  SVNITWSDPSPPADRL--ILNYSPRDEEEEMMEVSLDATKRHAVLMGLQPATEYIVNL-V 845

Query: 1156 LRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNG 1215
               G     PIV  + T + PP ++ + +N     + VSW          YR++  PT  
Sbjct: 846  AVHGTVTSEPIVGSITTGIDPPKDITI-SNVTKDSVMVSWS-PPVASFDYYRVSYRPT-- 901

Query: 1216 QQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPEVPQLTDLSF 1275
            Q G     VV    +  T   L+P  EY +S+ +V+  +ES  I   +   +    DL  
Sbjct: 902  QVGRLDSSVVPNTVTEFTITRLNPATEYEISLNSVRGREESERICTLVHTAMDNPVDLIA 961

Query: 1276 VDITDSSIGLRW-TPLNSSTIIGYRITV---VAAGEGIPIFEDFVDSSVGYYTVTGLEPG 1331
             +IT +   L+W  P+    +  Y I +     AGE I      VD     + +  L P 
Sbjct: 962  TNITPTEALLQWKAPVGE--VENYVIVLTHFAVAGETI-----LVDGVSEEFRLVDLLPS 1014

Query: 1332 IDYDISVITLINGGESAPTTLTQ-QTAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFL 1390
              Y  ++    NG  ++ T  T   T + PP +L  + +   +  ++W PP + ++ N++
Sbjct: 1015 THYTATMYA-TNGPLTSGTISTNFSTLLDPPANLTASEVTRQSALISWQPPRA-EIENYV 1072

Query: 1391 VRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLD 1450
            + Y          EL +   D  + L  LL  T+Y V + +  +                
Sbjct: 1073 LTYKSTDGSR--KELIVDAEDTWIRLEGLLENTDYTVLLQAAQD---------------- 1114

Query: 1451 SPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLT 1510
                  +S IT+ +FT          TG R+  HP        +D   H  N  TL+ + 
Sbjct: 1115 ----TTWSSITSTAFT----------TGGRVFPHP--------QDCAQHLMNGDTLSGVY 1152

Query: 1511 P 1511
            P
Sbjct: 1153 P 1153



 Score =  166 bits (421), Expect = 2e-40
 Identities = 159/647 (24%), Positives = 273/647 (42%), Gaps = 42/647 (6%)

Query: 610  GPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIK 669
            GP ++ + +         ++W  P+ + +   +L++      G      +   L+ Y+++
Sbjct: 506  GPTQILVRDVSDTVAF--VEWIPPR-AKVDFILLKYGLVGGEGGRTTFRLQPPLSQYSVQ 562

Query: 670  GLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVT 729
             L+PG  YE  + +++     +     FTT         N   G  T  S  +    S  
Sbjct: 563  ALRPGSRYEVSVSAVRGTNESDSATTQFTT---EIDAPKNLRVGSRTATSLDLEWDNSEA 619

Query: 730  EITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVN 789
            E+     V S      T++G +    L   G  P         T   + DL+PG +Y V 
Sbjct: 620  EVQEYKVVYS------TLAGEQYHEVLVPRGIGP--------TTRATLTDLVPGTEYGVG 665

Query: 790  VYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSV 849
            +  +  + +QS+  + +  T  D+P D  V    +TSI + W++   PI  YRI ++PS 
Sbjct: 666  ISAVM-NSQQSVPATMNARTELDSPRDLMVTASSETSISLIWTKASGPIDHYRITFTPS- 723

Query: 850  EGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPS 909
             G ++E+ +P+   S TL+DL+PG +Y I++ A    Q+S    +   T   P S     
Sbjct: 724  SGIASEVTVPKDRTSYTLTDLEPGAEYIISVTAERGRQQSLESTVDAFTGFRPISH---- 779

Query: 910  PRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSP 969
               L F  VT   V I W+ P        ++  P +   E  +    +    A + GL P
Sbjct: 780  ---LHFSHVTSSSVNITWSDPSPPADRLILNYSPRDEEEEMMEVSLDATKRHAVLMGLQP 836

Query: 970  GVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRL 1029
               Y   + AV     S+P+    TT +D P ++   N T  +V+V W+PP A    YR+
Sbjct: 837  ATEYIVNLVAVHGTVTSEPIVGSITTGIDPPKDITISNVTKDSVMVSWSPPVASFDYYRV 896

Query: 1030 TVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPK-ATGVFTTLQPG 1088
            +   T+ G+     V  +V+++ +  L PA+EY +SL +++G +ES +  T V T +   
Sbjct: 897  SYRPTQVGRLDSSVVPNTVTEFTITRLNPATEYEISLNSVRGREESERICTLVHTAMD-- 954

Query: 1089 SSIPPYNTEVTETTIVITW-TPAPRIGFKLGVRP--SQGGEAPREVTSDSGSIVVSGLTP 1145
            + +    T +T T  ++ W  P   +   + V    +  GE    V   S    +  L P
Sbjct: 955  NPVDLIATNITPTEALLQWKAPVGEVENYVIVLTHFAVAGETIL-VDGVSEEFRLVDLLP 1013

Query: 1146 GVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITG 1205
               Y  T+    +G      I     T L PP NL          L +SW+     +I  
Sbjct: 1014 STHYTATMYA-TNGPLTSGTISTNFSTLLDPPANLTASEVTRQSAL-ISWQ-PPRAEIEN 1070

Query: 1206 YRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKD 1252
            Y +T   T+G +    E +V A+ +    + L    +Y V +   +D
Sbjct: 1071 YVLTYKSTDGSR---KELIVDAEDTWIRLEGLLENTDYTVLLQAAQD 1114



 Score =  131 bits (330), Expect = 7e-30
 Identities = 77/296 (26%), Positives = 136/296 (45%), Gaps = 3/296 (1%)

Query: 1807 GTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSS 1866
            G   +A+  P DL+   ++  S+  +W  P + +T Y +   P    G   +  +  D S
Sbjct: 320  GPDCSAVAPPEDLRVAGISDRSIELEWDGP-MAVTEYVISYQPTALGGLQLQQRVPGDWS 378

Query: 1867 SVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWR 1926
             V ++ L     Y +SVYA+   + S P    V T  ++S P+  +    TETT+ + W 
Sbjct: 379  GVTITELEPGLTYNISVYAVISNILSLPITAKVAT--HLSTPQGLQFKTITETTVEVQWE 436

Query: 1927 TKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPV 1986
              + +  G+++  +P N +  +   +  DV S+  TGL+PG +Y + +  L + ARS P 
Sbjct: 437  PFSFSFDGWEISFIPKNNEGGVIAQVPSDVTSFNQTGLKPGEEYIVNVVALKEQARSPPT 496

Query: 1987 VIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGV 2046
                ST ID P+ +     +     V W PPRA++   ++KY   G        R +P +
Sbjct: 497  SASVSTVIDGPTQILVRDVSDTVAFVEWIPPRAKVDFILLKYGLVGGEGGRTTFRLQPPL 556

Query: 2047 TEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQKTPFVTHPGYDTGNGIQL 2102
            ++ ++  L PG+ Y + V A++   +S+    +  T    P     G  T   + L
Sbjct: 557  SQYSVQALRPGSRYEVSVSAVRGTNESDSATTQFTTEIDAPKNLRVGSRTATSLDL 612



 Score = 46.6 bits (109), Expect = 3e-04
 Identities = 57/225 (25%), Positives = 84/225 (37%), Gaps = 57/225 (25%)

Query: 1992 TAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATI 2051
            +A+  P +LR    +  S+ + W  P A +T Y+I Y+       ++  R     +  TI
Sbjct: 324  SAVAPPEDLRVAGISDRSIELEWDGPMA-VTEYVISYQPTALGGLQLQQRVPGDWSGVTI 382

Query: 2052 TGLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQKTPFVTHPGYDTGNGIQLPGTSGQQPS 2111
            T LEPG  Y I V A+ +N  S P+  +          TH    T  G+Q          
Sbjct: 383  TELEPGLTYNISVYAVISNILSLPITAK--------VATH--LSTPQGLQF--------- 423

Query: 2112 VGQQMIFEEHGFRRTTPPTTATPIRHRPRPYPPNVGQEALSQTTISWAPFQDTSE-YIIS 2170
                         +T   TT                        + W PF  + + + IS
Sbjct: 424  -------------KTITETTVE----------------------VQWEPFSFSFDGWEIS 448

Query: 2171 CHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQR 2215
              P   +E  +  +VP   TS   TGL  G  Y + V ALK+Q R
Sbjct: 449  FIPKN-NEGGVIAQVPSDVTSFNQTGLKPGEEYIVNVVALKEQAR 492


>gi|62988324 tenascin N [Homo sapiens]
          Length = 1299

 Score =  317 bits (811), Expect = 1e-85
 Identities = 235/815 (28%), Positives = 378/815 (46%), Gaps = 26/815 (3%)

Query: 1273 LSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGI 1332
            L  +  T+ S+ + W P  SS +  Y ++    G+ +   +  V      Y + GL PG 
Sbjct: 268  LQLLKNTEDSLLVSWEP--SSQVDHYLLSYYPLGKELSGKQIQVPKEQHSYEILGLLPGT 325

Query: 1333 DYDISVITLINGGESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVR 1392
             Y +++  + N   S+P  L   T +        T+   +++ V W  P S ++  + +R
Sbjct: 326  KYIVTLRNVKNEVSSSPQHLLATTDLAVLGTAWVTDETENSLDVEWENP-STEVDYYKLR 384

Query: 1393 YSPVKNEEDVAELSISPSDNAVV---LTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGL 1449
            Y P+  +E VAE+++  S +      +T L PGTEY ++V  +  + E  P+    +T +
Sbjct: 385  YGPMTGQE-VAEVTVPKSSDPKSRYDITGLHPGTEYKITVVPMRGELEGKPILLNGRTEI 443

Query: 1450 DSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNL 1509
            DSPT +    +T ++ TV W   +A I  Y +R+      G  +E  V    +S  LT L
Sbjct: 444  DSPTNVVTDRVTEDTATVSWDPVQAVIDKYVVRYTSA--DGDTKEMAVHKDESSTVLTGL 501

Query: 1510 TPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYY 1569
             PG  Y V + A  G + S        T  D P +L     T  +  ISWD    T+  Y
Sbjct: 502  KPGEAYKVYVWAERGNQGSKKADTNALTEIDSPANLVTDRVTENTATISWDPVQATIDKY 561

Query: 1570 RITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINY 1629
             + Y  +  +   +E  V   +S+  ++GL+PGV+YT+ V+A  G  +S    K    N 
Sbjct: 562  VVRY-TSADDQETREVLVGKEQSSTVLTGLRPGVEYTVHVWAQKGDRES----KKADTNA 616

Query: 1630 RTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMT 1689
             T+ID P  +    V +N  +V W P  + +  Y V  T  +  G T+    G +Q+   
Sbjct: 617  PTDIDSPKNLVTDRVTENMATVSWDPVQAAIDKYVVRYT--SAGGETREVPVGKEQSSTV 674

Query: 1690 IEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQ 1749
            + GL+P +EY+V V+AQ    ES+     A T+ID P+ L    V  +   ++W+  +  
Sbjct: 675  LTGLRPGMEYMVHVWAQKGDQESKKADTKAQTDIDSPQNLVTDRVTENMATVSWDPVRAT 734

Query: 1750 VSRYRVTYSSPEDGIHELFPAPDGEEDTAE-LQGLRPGSEYTVSVVALHDDMESQPLIGT 1808
            + RY V Y+S +DG  E    P G+E ++  L GLRPG EYTV V A     ES+     
Sbjct: 735  IDRYVVRYTSAKDG--ETREVPVGKEQSSTVLTGLRPGVEYTVHVWAQKGAQESKKADTK 792

Query: 1809 QSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSV 1868
              T I +P +L    VT  + +  W P    +  Y V  T     G  +E+ +  + SS 
Sbjct: 793  AQTDIDSPQNLVTDWVTENTATVSWDPVQATIDRYVVHYT--SANGETREVPVGKEQSST 850

Query: 1869 VVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTK 1928
            V++GL    +Y V V+A K    S+ A     T   +  P+       TE   T+SW   
Sbjct: 851  VLTGLRPGMEYTVHVWAQKGNQESKKADTKAQT--EIDGPKNLVTDWVTENMATVSWDPV 908

Query: 1929 TETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVI 1988
              TI  + V    A+G+T  +  +  +  S  +TGL+PG +Y ++++       S     
Sbjct: 909  QATIDKYMVRYTSADGETR-EVPVGKEHSSTVLTGLRPGMEYMVHVWAQKGAQESKKADT 967

Query: 1989 DASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTE 2048
             A T +D P NLR  A T +  +++W PP A+I GYI+ Y+ P    +E+          
Sbjct: 968  KAQTELDPPRNLRPSAVTQSGGILTWTPPSAQIHGYILTYQFPDGTVKEMQLGRED--QR 1025

Query: 2049 ATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTV 2083
              + GLE G  Y + ++A K  ++S  +     TV
Sbjct: 1026 FALQGLEQGATYPVSLVAFKGGRRSRNVSTTLSTV 1060



 Score =  313 bits (801), Expect = 2e-84
 Identities = 222/747 (29%), Positives = 346/747 (46%), Gaps = 25/747 (3%)

Query: 1358 VPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLT 1417
            V  P  L+      D++ V+W P   +D  ++L+ Y P+  E    ++ +    ++  + 
Sbjct: 262  VVTPQGLQLLKNTEDSLLVSWEPSSQVD--HYLLSYYPLGKELSGKQIQVPKEQHSYEIL 319

Query: 1418 NLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATIT 1477
             LLPGT+Y+V++ +V  +  S+P      T L        +D T NS  V W  P   + 
Sbjct: 320  GLLPGTKYIVTLRNVKNEVSSSPQHLLATTDLAVLGTAWVTDETENSLDVEWENPSTEVD 379

Query: 1478 GYRIRHHPEHFSGRP-REDRVPHS---RNSITLTNLTPGTEYVVSIVALNGREESPLLIG 1533
             Y++R+ P   +G+   E  VP S   ++   +T L PGTEY +++V + G  E   ++ 
Sbjct: 380  YYKLRYGP--MTGQEVAEVTVPKSSDPKSRYDITGLHPGTEYKITVVPMRGELEGKPILL 437

Query: 1534 QQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKST 1593
               T  D P ++     T  +  +SWD     +  Y + Y    G++  +E  V   +S+
Sbjct: 438  NGRTEIDSPTNVVTDRVTEDTATVSWDPVQAVIDKYVVRYTSADGDT--KEMAVHKDESS 495

Query: 1594 ATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKW 1653
              ++GLKPG  Y + V+A  G       SK    N  TEID P+ +    V +N+ ++ W
Sbjct: 496  TVLTGLKPGEAYKVYVWAERGN----QGSKKADTNALTEIDSPANLVTDRVTENTATISW 551

Query: 1654 LPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQ 1713
             P  + +  Y V  T  +    T+    G +Q+   + GL+P VEY V V+AQ    ES+
Sbjct: 552  DPVQATIDKYVVRYTSADDQ-ETREVLVGKEQSSTVLTGLRPGVEYTVHVWAQKGDRESK 610

Query: 1714 PLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDG 1773
                 A T+ID PK L    V  +   ++W+  Q  + +Y V Y+S      E+   P G
Sbjct: 611  KADTNAPTDIDSPKNLVTDRVTENMATVSWDPVQAAIDKYVVRYTSAGGETREV---PVG 667

Query: 1774 EEDTAE-LQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQ 1832
            +E ++  L GLRPG EY V V A   D ES+       T I +P +L   +VT    +  
Sbjct: 668  KEQSSTVLTGLRPGMEYMVHVWAQKGDQESKKADTKAQTDIDSPQNLVTDRVTENMATVS 727

Query: 1833 WTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTS 1892
            W P    +  Y VR T   K G  +E+ +  + SS V++GL    +Y V V+A K    S
Sbjct: 728  WDPVRATIDRYVVRYT-SAKDGETREVPVGKEQSSTVLTGLRPGVEYTVHVWAQKGAQES 786

Query: 1893 RPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTI 1952
            + A     T  ++  P+       TE T T+SW     TI  + V    ANG+T  +  +
Sbjct: 787  KKADTKAQT--DIDSPQNLVTDWVTENTATVSWDPVQATIDRYVVHYTSANGETR-EVPV 843

Query: 1953 KPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLV 2012
              +  S  +TGL+PG +Y ++++    N  S      A T ID P NL     T N   V
Sbjct: 844  GKEQSSTVLTGLRPGMEYTVHVWAQKGNQESKKADTKAQTEIDGPKNLVTDWVTENMATV 903

Query: 2013 SWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQK 2072
            SW P +A I  Y+++Y       REV        T   +TGL PG EY ++V A K  Q+
Sbjct: 904  SWDPVQATIDKYMVRYTSADGETREVPVGKEHSST--VLTGLRPGMEYMVHVWAQKGAQE 961

Query: 2073 SEPLIGRKKTVQKTPFVTHPGYDTGNG 2099
            S+    + +T    P    P   T +G
Sbjct: 962  SKKADTKAQTELDPPRNLRPSAVTQSG 988



 Score =  270 bits (689), Expect = 2e-71
 Identities = 197/637 (30%), Positives = 295/637 (46%), Gaps = 25/637 (3%)

Query: 1447 TGLD-----SPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSR 1501
            TGLD     +P G+     T +S  V W  P + +  Y + ++P       ++ +VP  +
Sbjct: 255  TGLDCAQVVTPQGLQLLKNTEDSLLVSW-EPSSQVDHYLLSYYPLGKELSGKQIQVPKEQ 313

Query: 1502 NSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDA 1561
            +S  +  L PGT+Y+V++  +     S       +T   V     V   T  SL + W+ 
Sbjct: 314  HSYEILGLLPGTKYIVTLRNVKNEVSSSPQHLLATTDLAVLGTAWVTDETENSLDVEWEN 373

Query: 1562 PAVTVRYYRITYGETGGNSPVQEFTVPGS---KSTATISGLKPGVDYTITVYAVTGRGDS 1618
            P+  V YY++ YG   G   V E TVP S   KS   I+GL PG +Y ITV  + G    
Sbjct: 374  PSTEVDYYKLRYGPMTGQE-VAEVTVPKSSDPKSRYDITGLHPGTEYKITVVPMRGE--- 429

Query: 1619 PASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKT 1678
                KPI +N RTEID P+ +    V +++ +V W P  + +  Y V  T  +  G TK 
Sbjct: 430  -LEGKPILLNGRTEIDSPTNVVTDRVTEDTATVSWDPVQAVIDKYVVRYT--SADGDTKE 486

Query: 1679 KTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDS 1738
                 D++   + GL+P   Y V V+A+  +  S+     A+T ID P  L    V  ++
Sbjct: 487  MAVHKDESSTVLTGLKPGEAYKVYVWAERGNQGSKKADTNALTEIDSPANLVTDRVTENT 546

Query: 1739 IKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAE-LQGLRPGSEYTVSVVALH 1797
              I+W+  Q  + +Y V Y+S +D   E      G+E ++  L GLRPG EYTV V A  
Sbjct: 547  ATISWDPVQATIDKYVVRYTSADD--QETREVLVGKEQSSTVLTGLRPGVEYTVHVWAQK 604

Query: 1798 DDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMK 1857
             D ES+       T I +P +L   +VT    +  W P    +  Y VR T     G  +
Sbjct: 605  GDRESKKADTNAPTDIDSPKNLVTDRVTENMATVSWDPVQAAIDKYVVRYT--SAGGETR 662

Query: 1858 EINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDAT 1917
            E+ +  + SS V++GL    +Y V V+A K    S+ A     T  ++  P+       T
Sbjct: 663  EVPVGKEQSSTVLTGLRPGMEYMVHVWAQKGDQESKKADTKAQT--DIDSPQNLVTDRVT 720

Query: 1918 ETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTL 1977
            E   T+SW     TI  + V    A      +  +  +  S  +TGL+PG +Y ++++  
Sbjct: 721  ENMATVSWDPVRATIDRYVVRYTSAKDGETREVPVGKEQSSTVLTGLRPGVEYTVHVWAQ 780

Query: 1978 NDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPRE 2037
                 S      A T ID+P NL     T N+  VSW P +A I  Y++ Y       RE
Sbjct: 781  KGAQESKKADTKAQTDIDSPQNLVTDWVTENTATVSWDPVQATIDRYVVHYTSANGETRE 840

Query: 2038 VVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSE 2074
            V        T   +TGL PG EYT++V A K NQ+S+
Sbjct: 841  VPVGKEQSST--VLTGLRPGMEYTVHVWAQKGNQESK 875



 Score =  261 bits (667), Expect = 6e-69
 Identities = 221/826 (26%), Positives = 366/826 (44%), Gaps = 39/826 (4%)

Query: 907  VPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVN--LPGEHGQRLPISRNTFAEV 964
            V +P+ LQ ++ T+  + + W P  S V  Y +   P+   L G+  Q +P  ++++ E+
Sbjct: 262  VVTPQGLQLLKNTEDSLLVSWEP-SSQVDHYLLSYYPLGKELSGKQIQ-VPKEQHSY-EI 318

Query: 965  TGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQI 1024
             GL PG  Y   +  V +   S P     TT L         +ET++++ V W  P  ++
Sbjct: 319  LGLLPGTKYIVTLRNVKNEVSSSPQHLLATTDLAVLGTAWVTDETENSLDVEWENPSTEV 378

Query: 1025 TGYRLTVGLTRRGQPRQYNVGPS---VSKYPLRNLQPASEYTVSLVAIKGNQE-SPKATG 1080
              Y+L  G     +  +  V  S    S+Y +  L P +EY +++V ++G  E  P    
Sbjct: 379  DYYKLRYGPMTGQEVAEVTVPKSSDPKSRYDITGLHPGTEYKITVVPMRGELEGKPILLN 438

Query: 1081 VFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVR--PSQGGEAPREVTSDSGSI 1138
              T +   +++      VTE T  ++W P   +  K  VR   + G      V  D  S 
Sbjct: 439  GRTEIDSPTNV--VTDRVTEDTATVSWDPVQAVIDKYVVRYTSADGDTKEMAVHKDESST 496

Query: 1139 VVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERS 1198
            V++GL PG  Y   +   R  Q       N  +T +  P NL  +   +    T+SW+  
Sbjct: 497  VLTGLKPGEAYKVYVWAERGNQGSKKADTN-ALTEIDSPANLVTDRVTE-NTATISWD-P 553

Query: 1199 TTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVP 1258
                I  Y +  T  + Q+  + E +V  +QSS     L PG+EY V V+  K D+ES  
Sbjct: 554  VQATIDKYVVRYTSADDQE--TREVLVGKEQSSTVLTGLRPGVEYTVHVWAQKGDRESKK 611

Query: 1259 ISDTIIPEVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAG---EGIPIFEDF 1315
                   ++    +L    +T++   + W P+ ++ I  Y +   +AG     +P+ ++ 
Sbjct: 612  ADTNAPTDIDSPKNLVTDRVTENMATVSWDPVQAA-IDKYVVRYTSAGGETREVPVGKE- 669

Query: 1316 VDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAVPPPTDLRFTNIGPDTMR 1375
              SS     +TGL PG++Y + V       ES       QT +  P +L    +  +   
Sbjct: 670  -QSST---VLTGLRPGMEYMVHVWAQKGDQESKKADTKAQTDIDSPQNLVTDRVTENMAT 725

Query: 1376 VTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQ 1435
            V+W  P    +  ++VRY+  K+ E   E+ +    ++ VLT L PG EY V V +    
Sbjct: 726  VSW-DPVRATIDRYVVRYTSAKDGE-TREVPVGKEQSSTVLTGLRPGVEYTVHVWAQKGA 783

Query: 1436 HESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPRED 1495
             ES     + +T +DSP  +    +T N+ TV W   +ATI  Y +  H    +G  RE 
Sbjct: 784  QESKKADTKAQTDIDSPQNLVTDWVTENTATVSWDPVQATIDRYVV--HYTSANGETREV 841

Query: 1496 RVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSL 1555
             V   ++S  LT L PG EY V + A  G +ES     +  T  D P++L     T    
Sbjct: 842  PVGKEQSSTVLTGLRPGMEYTVHVWAQKGNQESKKADTKAQTEIDGPKNLVTDWVTENMA 901

Query: 1556 LISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGR 1615
             +SWD    T+  Y + Y  T  +   +E  V    S+  ++GL+PG++Y + V+A  G 
Sbjct: 902  TVSWDPVQATIDKYMVRY--TSADGETREVPVGKEHSSTVLTGLRPGMEYMVHVWAQKGA 959

Query: 1616 GDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGP 1675
             +    SK      +TE+D P  ++ + V  +   + W P S+ + GY +T   +   G 
Sbjct: 960  QE----SKKADTKAQTELDPPRNLRPSAVTQSGGILTWTPPSAQIHGYILTY--QFPDGT 1013

Query: 1676 TKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVT 1721
             K    G +     ++GL+    Y VS+ A      S+ +  T  T
Sbjct: 1014 VKEMQLGREDQRFALQGLEQGATYPVSLVAFKGGRRSRNVSTTLST 1059



 Score =  225 bits (574), Expect = 4e-58
 Identities = 227/841 (26%), Positives = 360/841 (42%), Gaps = 61/841 (7%)

Query: 636  SHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRF 695
            S +  Y+L + P       K+  +P   +SY I GL PG                  T++
Sbjct: 286  SQVDHYLLSYYPLGKELSGKQIQVPKEQHSYEILGLLPG------------------TKY 327

Query: 696  DFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYE 755
              T  +    V+S+      T    ++ T+  VT+ T +S  V W + S  V  +++ Y 
Sbjct: 328  IVTLRNVKNEVSSSPQHLLATTDLAVLGTA-WVTDETENSLDVEWENPSTEVDYYKLRYG 386

Query: 756  LSEEGDEPQYLDLPSTA---TSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPD 812
                G E   + +P ++   +  +I  L PG +Y + V  +  + E   IL   +T   D
Sbjct: 387  -PMTGQEVAEVTVPKSSDPKSRYDITGLHPGTEYKITVVPMRGELEGKPILLNGRTEI-D 444

Query: 813  APPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQP 872
            +P +   D+V + +  V W   QA I  Y + Y+ S +G + E+ + +  +S  L+ L+P
Sbjct: 445  SPTNVVTDRVTEDTATVSWDPVQAVIDKYVVRYT-SADGDTKEMAVHKDESSTVLTGLKP 503

Query: 873  GVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPES 932
            G  Y + ++A   NQ S       +   T     + SP +L    VT+   TI W P ++
Sbjct: 504  GEAYKVYVWAERGNQGS-------KKADTNALTEIDSPANLVTDRVTENTATISWDPVQA 556

Query: 933  AVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQ 992
             +  Y V     +   E  + L     +   +TGL PGV Y   V+A    RESK     
Sbjct: 557  TIDKYVVRYTSAD-DQETREVLVGKEQSSTVLTGLRPGVEYTVHVWAQKGDRESKKADTN 615

Query: 993  QTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYP 1052
              T +D+P NL     T++   V W P +A I  Y +    +  G+ R+  VG   S   
Sbjct: 616  APTDIDSPKNLVTDRVTENMATVSWDPVQAAIDKYVVRY-TSAGGETREVPVGKEQSSTV 674

Query: 1053 LRNLQPASEYTVSLVAIKGNQESPKA-TGVFTTLQPGSSIPPYNTEVTETTIVITWTPAP 1111
            L  L+P  EY V + A KG+QES KA T   T +    ++      VTE    ++W P  
Sbjct: 675  LTGLRPGMEYMVHVWAQKGDQESKKADTKAQTDIDSPQNL--VTDRVTENMATVSWDPVR 732

Query: 1112 RIGFKLGVR--PSQGGEAPREVT--SDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIV 1167
                +  VR   ++ GE  REV    +  S V++GL PGVEY   +   +  QE      
Sbjct: 733  ATIDRYVVRYTSAKDGET-REVPVGKEQSSTVLTGLRPGVEYTVHVWAQKGAQE-SKKAD 790

Query: 1168 NKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHA 1227
             K  T +  P NL  +   +    TVSW+      I  Y +  T  NG+   + E  V  
Sbjct: 791  TKAQTDIDSPQNLVTDWVTE-NTATVSWD-PVQATIDRYVVHYTSANGE---TREVPVGK 845

Query: 1228 DQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPEVPQLTDLSFVDITDSSIGLRW 1287
            +QSS     L PG+EY V V+  K ++ES         E+    +L    +T++   + W
Sbjct: 846  EQSSTVLTGLRPGMEYTVHVWAQKGNQESKKADTKAQTEIDGPKNLVTDWVTENMATVSW 905

Query: 1288 TPLNSSTIIGYRITVVAA-GE--GIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLING 1344
             P+  +TI  Y +   +A GE   +P+ ++   +      +TGL PG++Y + V      
Sbjct: 906  DPV-QATIDKYMVRYTSADGETREVPVGKEHSST-----VLTGLRPGMEYMVHVWAQKGA 959

Query: 1345 GESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAE 1404
             ES       QT + PP +LR + +      +TW  PPS  +  +++ Y     +  V E
Sbjct: 960  QESKKADTKAQTELDPPRNLRPSAVTQSGGILTWT-PPSAQIHGYILTYQ--FPDGTVKE 1016

Query: 1405 LSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKT-GLDSPTGIDFSDITAN 1463
            + +   D    L  L  G  Y VS+ +      S  +     T G   P   D S +  N
Sbjct: 1017 MQLGREDQRFALQGLEQGATYPVSLVAFKGGRRSRNVSTTLSTVGARFPHPSDCSQVQQN 1076

Query: 1464 S 1464
            S
Sbjct: 1077 S 1077



 Score =  220 bits (560), Expect = 2e-56
 Identities = 210/756 (27%), Positives = 330/756 (43%), Gaps = 57/756 (7%)

Query: 619  TPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNS---YTIKGLKPGV 675
            T    NS  ++W  P  + +  Y LR+ P        E T+P   +    Y I GL PG 
Sbjct: 360  TDETENSLDVEWENPS-TEVDYYKLRYGPMTGQ-EVAEVTVPKSSDPKSRYDITGLHPGT 417

Query: 676  VYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASS 735
             Y+  ++ ++  G  E             P+  N   G T   SP    ++ VTE TA+ 
Sbjct: 418  EYKITVVPMR--GELE-----------GKPILLN---GRTEIDSPTNVVTDRVTEDTAT- 460

Query: 736  FVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISE 795
              VSW      +  + V Y  S +GD  + + +    +S  +  L PG  Y   VY  +E
Sbjct: 461  --VSWDPVQAVIDKYVVRYT-SADGDTKE-MAVHKDESSTVLTGLKPGEAY--KVYVWAE 514

Query: 796  DGEQ-SLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSST 854
             G Q S    T+  T  D+P +   D+V + +  + W   QA I  Y + Y+ + +  + 
Sbjct: 515  RGNQGSKKADTNALTEIDSPANLVTDRVTENTATISWDPVQATIDKYVVRYTSADDQETR 574

Query: 855  ELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQ 914
            E+ + +  +S  L+ L+PGV+Y + ++A + ++ES     ++  T  P    + SP++L 
Sbjct: 575  EVLVGKEQSSTVLTGLRPGVEYTVHVWAQKGDRES-----KKADTNAPTD--IDSPKNLV 627

Query: 915  FVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEV-TGLSPGVTY 973
               VT+   T+ W P ++A+  Y   V+     G   + +P+ +   + V TGL PG+ Y
Sbjct: 628  TDRVTENMATVSWDPVQAAIDKY---VVRYTSAGGETREVPVGKEQSSTVLTGLRPGMEY 684

Query: 974  YFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGL 1033
               V+A    +ESK    +  T +D+P NL     T++   V W P RA I  Y +    
Sbjct: 685  MVHVWAQKGDQESKKADTKAQTDIDSPQNLVTDRVTENMATVSWDPVRATIDRYVVRYTS 744

Query: 1034 TRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKA-TGVFTTLQPGSSIP 1092
             + G+ R+  VG   S   L  L+P  EYTV + A KG QES KA T   T +    ++ 
Sbjct: 745  AKDGETREVPVGKEQSSTVLTGLRPGVEYTVHVWAQKGAQESKKADTKAQTDIDSPQNL- 803

Query: 1093 PYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVT--SDSGSIVVSGLTPGVEYV 1150
                 VTE T  ++W P      +  V  +      REV    +  S V++GL PG+EY 
Sbjct: 804  -VTDWVTENTATVSWDPVQATIDRYVVHYTSANGETREVPVGKEQSSTVLTGLRPGMEYT 862

Query: 1151 YTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITT 1210
              +   +  QE       K  T +  P NL  +   +  + TVSW+      I  Y +  
Sbjct: 863  VHVWAQKGNQE-SKKADTKAQTEIDGPKNLVTDWVTE-NMATVSWD-PVQATIDKYMVRY 919

Query: 1211 TPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPEVPQL 1270
            T  +G+   + E  V  + SS     L PG+EY V V+  K  +ES         E+   
Sbjct: 920  TSADGE---TREVPVGKEHSSTVLTGLRPGMEYMVHVWAQKGAQESKKADTKAQTELDPP 976

Query: 1271 TDLSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEP 1330
             +L    +T S   L WTP  S+ I GY +T       +   E  +      + + GLE 
Sbjct: 977  RNLRPSAVTQSGGILTWTP-PSAQIHGYILTYQFPDGTVK--EMQLGREDQRFALQGLEQ 1033

Query: 1331 GIDYDISVITLINGGESAPTTLTQQTA---VPPPTD 1363
            G  Y +S++    G  S   + T  T     P P+D
Sbjct: 1034 GATYPVSLVAFKGGRRSRNVSTTLSTVGARFPHPSD 1069



 Score =  192 bits (487), Expect = 4e-48
 Identities = 168/669 (25%), Positives = 281/669 (42%), Gaps = 60/669 (8%)

Query: 1632 EIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIE 1691
            ++  P  +Q+    ++S+ V W PSS  V  Y ++  P       K      +Q    I 
Sbjct: 261  QVVTPQGLQLLKNTEDSLLVSWEPSSQ-VDHYLLSYYPLGKELSGKQIQVPKEQHSYEIL 319

Query: 1692 GLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVS 1751
            GL P  +Y+V++        S P    A T++        TD   +S+ + WE+P  +V 
Sbjct: 320  GLLPGTKYIVTLRNVKNEVSSSPQHLLATTDLAVLGTAWVTDETENSLDVEWENPSTEVD 379

Query: 1752 RYRVTYS--SPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQ 1809
             Y++ Y   + ++      P     +   ++ GL PG+EY ++VV +  ++E +P++   
Sbjct: 380  YYKLRYGPMTGQEVAEVTVPKSSDPKSRYDITGLHPGTEYKITVVPMRGELEGKPILLNG 439

Query: 1810 STAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVV 1869
             T I +PT++   +VT  + +  W P    +  Y VR T  +  G  KE+ +  D SS V
Sbjct: 440  RTEIDSPTNVVTDRVTEDTATVSWDPVQAVIDKYVVRYTSAD--GDTKEMAVHKDESSTV 497

Query: 1870 VSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKT 1929
            ++GL     Y+V V+A +    S+ A      L  +  P        TE T TISW    
Sbjct: 498  LTGLKPGEAYKVYVWAERGNQGSKKAD--TNALTEIDSPANLVTDRVTENTATISWDPVQ 555

Query: 1930 ETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVID 1989
             TI  + V    A+ Q   +  +  +  S  +TGL+PG +Y ++++    +  S     +
Sbjct: 556  ATIDKYVVRYTSADDQETREVLVGKEQSSTVLTGLRPGVEYTVHVWAQKGDRESKKADTN 615

Query: 1990 ASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEA 2049
            A T ID+P NL     T N   VSW P +A I  Y+++Y   G   REV        T  
Sbjct: 616  APTDIDSPKNLVTDRVTENMATVSWDPVQAAIDKYVVRYTSAGGETREVPVGKEQSST-- 673

Query: 2050 TITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQKTP---------------------- 2087
             +TGL PG EY ++V A K +Q+S+    + +T   +P                      
Sbjct: 674  VLTGLRPGMEYMVHVWAQKGDQESKKADTKAQTDIDSPQNLVTDRVTENMATVSWDPVRA 733

Query: 2088 -----FVTHPGYDTGNGIQLP--------GTSGQQPSVGQQM-IFEEHGFRRTTPPTTAT 2133
                  V +     G   ++P          +G +P V   + ++ + G + +    T  
Sbjct: 734  TIDRYVVRYTSAKDGETREVPVGKEQSSTVLTGLRPGVEYTVHVWAQKGAQESKKADTKA 793

Query: 2134 PIRHRPRPYPPNVGQEALSQ--TTISWAPFQDT-SEYIISCHPVGTDEEPLQFRVPGTST 2190
                     P N+  + +++   T+SW P Q T   Y++  H    + E  +  V    +
Sbjct: 794  ---QTDIDSPQNLVTDWVTENTATVSWDPVQATIDRYVV--HYTSANGETREVPVGKEQS 848

Query: 2191 SATLTGLTRGATYNIIVEALKDQQRH-----KVREEVVTVGNSVNEGLNQPTDDSCFDPY 2245
            S  LTGL  G  Y + V A K  Q       K + E+    N V + + +      +DP 
Sbjct: 849  STVLTGLRPGMEYTVHVWAQKGNQESKKADTKAQTEIDGPKNLVTDWVTENMATVSWDPV 908

Query: 2246 --TVSHYAV 2252
              T+  Y V
Sbjct: 909  QATIDKYMV 917



 Score = 37.0 bits (84), Expect = 0.24
 Identities = 34/127 (26%), Positives = 54/127 (42%), Gaps = 14/127 (11%)

Query: 2143 PPNVGQEALSQTT--ISWAPFQDTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRG 2200
            P N+  + +++ T  ISW P Q T +  +  +    D+E  +  V    +S  LTGL  G
Sbjct: 534  PANLVTDRVTENTATISWDPVQATIDKYVVRYTSADDQETREVLVGKEQSSTVLTGLRPG 593

Query: 2201 ATYNIIVEALK-DQQRHKVREEVVT--------VGNSVNEGLNQPTDD---SCFDPYTVS 2248
              Y + V A K D++  K      T        V + V E +   + D   +  D Y V 
Sbjct: 594  VEYTVHVWAQKGDRESKKADTNAPTDIDSPKNLVTDRVTENMATVSWDPVQAAIDKYVVR 653

Query: 2249 HYAVGDE 2255
            + + G E
Sbjct: 654  YTSAGGE 660


>gi|188528648 tenascin XB isoform 1 precursor [Homo sapiens]
          Length = 4242

 Score =  308 bits (790), Expect = 3e-83
 Identities = 371/1677 (22%), Positives = 642/1677 (38%), Gaps = 237/1677 (14%)

Query: 616  ITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGV 675
            +T T S P+S  + W  PQ      + ++++ ++  GR +   + G  +  T+ GL+PG 
Sbjct: 2417 LTVTGSSPDSLSLSWTVPQ-GRFDSFTVQYKDRD--GRPQVVRVGGEESEVTVGGLEPGR 2473

Query: 676  VYEGQLISIQQYGHQEVTRFD-FTTTSTSTPVTSNTVTGETT---------PFSPLVATS 725
             Y+  L     YG  E  R    +T   + P      T   T         P  PL+   
Sbjct: 2474 KYKMHL-----YGLHEGRRVGPVSTVGVTAPQEDVDETPSPTEPGTEAPGPPEEPLLGEL 2528

Query: 726  ESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRK 785
             +VT  +  S  +SW         F V+Y+  +    PQ + +    + V +  L PGRK
Sbjct: 2529 -TVTGSSPDSLSLSWTVPQGRFDSFTVQYK--DRDGRPQAVRVGGQESKVTVRGLEPGRK 2585

Query: 786  YIVNVYQISED---GEQSLILSTSQ---------TTAPDAPPDPTVDQVDDT-----SIV 828
            Y +++Y + E    G  S +  T           T  P+ P  P + ++  T     S+ 
Sbjct: 2586 YKMHLYGLHEGRRLGPVSAVGVTEDEAETTQAVPTMTPEPPIKPRLGELTMTDATPDSLS 2645

Query: 829  VRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQE 888
            + W+ P+     + + Y    +G    + +P   + VT+S L+P  +Y + +Y     Q 
Sbjct: 2646 LSWTVPEGQFDHFLVQYRNG-DGQPKAVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQR 2704

Query: 889  STPVVI-----QQETTGTPRSDTVPSPRDLQFVEVTDVKVT--------IMWTPPESAVT 935
              P+ +      +E T +P   +  +P   +   + ++ VT        + WT P+    
Sbjct: 2705 VGPISVIGVTAAEEETPSPTELSTEAPEPPEEPLLGELTVTGSSPDSLSLSWTIPQG--- 2761

Query: 936  GYRVDVIPVNLPGEHGQ-RLPISRNTFAEVT--GLSPGVTYYFKVFAVSHGRESKPLTAQ 992
                D   V      G+ ++   R   +EVT  GL PG  Y   ++ +  GR   P++  
Sbjct: 2762 --HFDSFTVQYKDRDGRPQVMRVRGEESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVSTV 2819

Query: 993  QTTKLDAPTN------------------LQFVNETDSTVLVRWTPPRAQITGYRLTVGLT 1034
              T+ +A T                   L   + T  ++ + W  P  Q   + L     
Sbjct: 2820 GVTEDEAETTQAVPTTTPEPPNKPRLGELTVTDATPDSLSLSWMVPEGQFDHF-LVQYRN 2878

Query: 1035 RRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTL--------- 1085
              GQP+   V        +  L+P  +Y ++L    G Q     + +  T          
Sbjct: 2879 GDGQPKVVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPISVIGVTAAEEETPAPT 2938

Query: 1086 QPGSSIP-----PYNTEVTET-----TIVITWT-PAPRI-GFKLGVRPSQGGEAPREVTS 1133
            +P +  P     P   E+T T     ++ ++WT P  R   F +  +   G      V  
Sbjct: 2939 EPSTEAPEPPEEPLLGELTVTGSSPDSLSLSWTIPQGRFDSFTVQYKDRDGRPQVVRVRG 2998

Query: 1134 DSGSIVVSGLTPGVEYVYTIQVLRDGQERD--------APIVNKVVTPLSPPTNLHLEAN 1185
            +   + V GL PG +Y   +  L +GQ           AP      T   P         
Sbjct: 2999 EESEVTVGGLEPGCKYKMHLYGLHEGQRVGPVSAVGVTAPKDEAETTQAVPTMTPEPPIK 3058

Query: 1186 PDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHAD-----------QSSCTF 1234
            P  G LTV+     TPD     ++     GQ  + L +  + D           +   T 
Sbjct: 3059 PRLGELTVT---DATPD--SLSLSWMVPEGQFDHFLVQYRNGDGQPKAVRVPGHEDGVTI 3113

Query: 1235 DNLSPGLEYNVSVYTVKDDKESVPISDTII------------------PEVPQLTDLSFV 1276
              L P  +Y +++Y     +   P+S   +                  PE P L +L+  
Sbjct: 3114 SGLEPDHKYKMNLYGFHGGQRVGPVSAIGVTEEETPSPTEPSTEAPEAPEEPLLGELTVT 3173

Query: 1277 DITDSSIGLRWTP----LNSSTII-----GYRITVVAAGEGIPIFEDFVDSSVGYYTVTG 1327
              +  S+ L WT      +S T+      G    V   GE         +S V   TV G
Sbjct: 3174 GSSPDSLSLSWTVPQGRFDSFTVQYKDRDGQPQVVRVRGE---------ESEV---TVGG 3221

Query: 1328 LEPGIDYDISVITLINGGESAPTTLTQQTAVPPPT---------DLRFTNIGPDTMRVTW 1378
            LEPG  Y + +  L  G    P +    TA P PT         +L    +  D++ ++W
Sbjct: 3222 LEPGRKYKMHLYGLHEGQRVGPVSTVGITA-PLPTPLPVEPRLGELAVAAVTSDSVGLSW 3280

Query: 1379 APPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHES 1438
                     +FLV+Y   + +     + +S    AV ++ L P  +Y   +  +      
Sbjct: 3281 TVAQG-PFDSFLVQYRDAQGQPQA--VPVSGDLRAVAVSGLDPARKYKFLLFGLQNGKRH 3337

Query: 1439 TPLRGRQKTGLDSPTG-----IDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPR 1493
             P+    +T  D+        +  +D T +S  + W  P      + +++  +   GR +
Sbjct: 3338 GPVPVEARTAPDTKPSPRLGELTVTDATPDSVGLSWTVPEGEFDSFVVQYKDK--DGRLQ 3395

Query: 1494 EDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTV---SDVPR---DLEV 1547
               V  ++  +T+  L P  +Y   +  L+GR+    +    +T     ++P    +L V
Sbjct: 3396 VVPVAANQREVTVQGLEPSRKYRFLLYGLSGRKRLGPISADSTTAPLEKELPPHLGELTV 3455

Query: 1548 VAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTI 1607
               T +SL +SW         + + Y +T G    +   V   + T T+  L+PG  Y  
Sbjct: 3456 AEETSSSLRLSWTVAQGPFDSFVVQYRDTDGQP--RAVPVAADQRTVTVEDLEPGKKYKF 3513

Query: 1608 TVYAVTG---------------RGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVK 1652
             +Y + G                 D+PA           E  +   + VTD   +S+ + 
Sbjct: 3514 LLYGLLGGKRLGPVSALGMTAPEEDTPAPELAPEAPEPPEEPRLGVLTVTDTTPDSMRLS 3573

Query: 1653 WLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGES 1712
            W  +  P   + V     NG  P      G DQ+++ I GL+P+  Y   +Y  +     
Sbjct: 3574 WSVAQGPFDSFVVQYEDTNGQ-PQALLVDG-DQSKILISGLEPSTPYRFLLYGLHEGKRL 3631

Query: 1713 QPLVQTAVTNI---------DRPK--GLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPE 1761
             PL     T +          RP+   L+ TDV   S+++ WE+P G    + + +  P 
Sbjct: 3632 GPLSAEGTTGLAPAGQTSEESRPRLSQLSVTDVTTSSLRLNWEAPPGAFDSFLLRFGVPS 3691

Query: 1762 DGIHELFPAP--------DGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAI 1813
                E  P P         G   +A L+ LR G+ Y++++  L    ++  + GT  T  
Sbjct: 3692 PSTLEPHPRPLLQRELMVPGTRHSAVLRDLRSGTLYSLTLYGLRGPHKADSIQGTARTLS 3751

Query: 1814 P---APTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVV 1870
            P   +P DL+F+++  TS    W PP  +   ++V     +   P + + +   + +  +
Sbjct: 3752 PVLESPRDLQFSEIRETSAKVNWMPPPSRADSFKVSYQLADGGEP-QSVQVDGQARTQKL 3810

Query: 1871 SGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTE 1930
             GL+   +YEV+V +++    S P  G +TT+ +   P + R  + TE    + W+    
Sbjct: 3811 QGLIPGARYEVTVVSVRGFEESEPLTGFLTTVPD--GPTQLRALNLTEGFAVLHWKPPQN 3868

Query: 1931 TITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDA 1990
             +  + V  V A G  P+Q         Y +  L   T+Y   +  L     +SP  I  
Sbjct: 3869 PVDTYDVQ-VTAPGAPPLQAETPGSAVDYPLHDLVLHTNYTATVRGLRGPNLTSPASITF 3927

Query: 1991 STAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEAT 2050
            +T ++AP +L     TP + L++W  P  R  GY++ +  PG   +E++     G+T   
Sbjct: 3928 TTGLEAPRDLEAKEVTPRTALLTWTEPPVRPAGYLLSFHTPGGQNQEIL--LPGGITSHQ 3985

Query: 2051 ITGLEPGTEYTIYVIALKNNQKSEPLIGRKKT-VQKTPFVTHPGYDTGNGIQLPGTS 2106
            + GL P T Y   + A+       P+     T   + PF    G +  NG     TS
Sbjct: 3986 LLGLFPSTSYNARLQAMWGQSLLPPVSTSFTTGGLRIPFPRDCGEEMQNGAGASRTS 4042



 Score =  304 bits (778), Expect = 8e-82
 Identities = 359/1660 (21%), Positives = 629/1660 (37%), Gaps = 246/1660 (14%)

Query: 616  ITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGV 675
            +T T + P+S  + W  P+      +++++  KN  G+ K   +PGH +  TI GL+P  
Sbjct: 2309 LTVTDATPDSLSLSWTVPE-GQFDHFLVQY--KNGDGQPKATRVPGHEDRVTISGLEPDN 2365

Query: 676  VYEGQLISIQQYGHQEV---TRFDFTTTSTSTPV-TSNTVTGETTPFSPLVATSESVTEI 731
             Y+  L     +G Q V   +    T     TP  T  ++     P  PL+    +VT  
Sbjct: 2366 KYKMNLYGF--HGGQRVGPVSAIGVTAAEEETPSPTEPSMEAPEPPEEPLLGEL-TVTGS 2422

Query: 732  TASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVY 791
            +  S  +SW         F V+Y+  +    PQ + +    + V +  L PGRKY +++Y
Sbjct: 2423 SPDSLSLSWTVPQGRFDSFTVQYK--DRDGRPQVVRVGGEESEVTVGGLEPGRKYKMHLY 2480

Query: 792  QI-----------------SEDGEQSLILSTSQTTAPDAPPDPTVDQVDDT-----SIVV 829
             +                  ED +++   +   T AP  P +P + ++  T     S+ +
Sbjct: 2481 GLHEGRRVGPVSTVGVTAPQEDVDETPSPTEPGTEAPGPPEEPLLGELTVTGSSPDSLSL 2540

Query: 830  RWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQES 889
             W+ PQ     + + Y    +G    + +    + VT+  L+PG +Y + +Y + E +  
Sbjct: 2541 SWTVPQGRFDSFTVQYKDR-DGRPQAVRVGGQESKVTVRGLEPGRKYKMHLYGLHEGRRL 2599

Query: 890  TPV-----------VIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYR 938
             PV             Q   T TP     P   +L   + T   +++ WT PE      +
Sbjct: 2600 GPVSAVGVTEDEAETTQAVPTMTPEPPIKPRLGELTMTDATPDSLSLSWTVPEG-----Q 2654

Query: 939  VDVIPVNLPGEHGQ----RLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQT 994
             D   V      GQ    R+P        ++GL P   Y   ++    G+   P++    
Sbjct: 2655 FDHFLVQYRNGDGQPKAVRVP-GHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPISVIGV 2713

Query: 995  TKLDAPT--------------------NLQFVNETDSTVLVRWTPPRAQITGYRLTVGLT 1034
            T  +  T                     L     +  ++ + WT P+     + +     
Sbjct: 2714 TAAEEETPSPTELSTEAPEPPEEPLLGELTVTGSSPDSLSLSWTIPQGHFDSFTVQYK-D 2772

Query: 1035 RRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAI-KGNQESPKAT-GVF------TTLQ 1086
            R G+P+   V    S+  +  L+P  +Y + L  + +G +  P +T GV       T   
Sbjct: 2773 RDGRPQVMRVRGEESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVSTVGVTEDEAETTQAV 2832

Query: 1087 PGSSIPPYN---------TEVTETTIVITW-TPAPRIG-FKLGVRPSQGGEAPREVTSDS 1135
            P ++  P N         T+ T  ++ ++W  P  +   F +  R   G      V    
Sbjct: 2833 PTTTPEPPNKPRLGELTVTDATPDSLSLSWMVPEGQFDHFLVQYRNGDGQPKVVRVPGHE 2892

Query: 1136 GSIVVSGLTPGVEYVYTIQVLRDGQERDAPI----VNKVVTPLSPPTNLHLEA-----NP 1186
              + +SGL P  +Y   +     GQ R  PI    V         PT    EA      P
Sbjct: 2893 DGVTISGLEPDHKYKMNLYGFHGGQ-RVGPISVIGVTAAEEETPAPTEPSTEAPEPPEEP 2951

Query: 1187 DTGVLTVSWERSTTPDITGYRIT---------TTPTNGQQGNSLEEVVHADQSSCTFDNL 1237
              G LTV+    ++PD      T         T     + G      V  ++S  T   L
Sbjct: 2952 LLGELTVT---GSSPDSLSLSWTIPQGRFDSFTVQYKDRDGRPQVVRVRGEESEVTVGGL 3008

Query: 1238 SPGLEYNVSVYTV-----------------KDDKESVPISDTIIPEVP---QLTDLSFVD 1277
             PG +Y + +Y +                 KD+ E+     T+ PE P   +L +L+  D
Sbjct: 3009 EPGCKYKMHLYGLHEGQRVGPVSAVGVTAPKDEAETTQAVPTMTPEPPIKPRLGELTVTD 3068

Query: 1278 ITDSSIGLRWTPLNSST---IIGYRITVVAAGEG------IPIFEDFVDSSVGYYTVTGL 1328
             T  S+ L W          ++ YR      G+G      +P  ED V       T++GL
Sbjct: 3069 ATPDSLSLSWMVPEGQFDHFLVQYR-----NGDGQPKAVRVPGHEDGV-------TISGL 3116

Query: 1329 EPGIDYDISVITLINGGESAPTTLTQQTA--VPPPTD----------------LRFTNIG 1370
            EP   Y +++     G    P +    T    P PT+                L  T   
Sbjct: 3117 EPDHKYKMNLYGFHGGQRVGPVSAIGVTEEETPSPTEPSTEAPEAPEEPLLGELTVTGSS 3176

Query: 1371 PDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVS 1430
            PD++ ++W  P      +F V+Y     +  V    +   ++ V +  L PG +Y + + 
Sbjct: 3177 PDSLSLSWTVPQG-RFDSFTVQYKDRDGQPQVVR--VRGEESEVTVGGLEPGRKYKMHLY 3233

Query: 1431 SVYEQHESTPLRGRQKTG-LDSPTGID-------FSDITANSFTVHWIAPRATITGYRIR 1482
             ++E     P+     T  L +P  ++        + +T++S  + W   +     + ++
Sbjct: 3234 GLHEGQRVGPVSTVGITAPLPTPLPVEPRLGELAVAAVTSDSVGLSWTVAQGPFDSFLVQ 3293

Query: 1483 HHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVAL-NGREESPLLIGQQSTVSDV 1541
            +      G+P+   V     ++ ++ L P  +Y   +  L NG+   P+ +  ++     
Sbjct: 3294 YRDAQ--GQPQAVPVSGDLRAVAVSGLDPARKYKFLLFGLQNGKRHGPVPVEARTAPDTK 3351

Query: 1542 PR----DLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATIS 1597
            P     +L V  ATP S+ +SW  P      + + Y +  G   +Q   V  ++   T+ 
Sbjct: 3352 PSPRLGELTVTDATPDSVGLSWTVPEGEFDSFVVQYKDKDGR--LQVVPVAANQREVTVQ 3409

Query: 1598 GLKPGVDYTITVYAVTGRGD-SPASSKPISINYRTEIDKP-SQMQVTDVQDNSISVKWLP 1655
            GL+P   Y   +Y ++GR    P S+   +     E+     ++ V +   +S+ + W  
Sbjct: 3410 GLEPSRKYRFLLYGLSGRKRLGPISADSTTAPLEKELPPHLGELTVAEETSSSLRLSWTV 3469

Query: 1656 SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYV--------------V 1701
            +  P   + V    ++  G  +      DQ  +T+E L+P  +Y               V
Sbjct: 3470 AQGPFDSFVVQY--RDTDGQPRAVPVAADQRTVTVEDLEPGKKYKFLLYGLLGGKRLGPV 3527

Query: 1702 SVYAQNPSGESQPLVQTAVTNIDRPKG-----LAFTDVDVDSIKIAWESPQGQVSRYRVT 1756
            S        E  P  + A    + P+      L  TD   DS++++W   QG    + V 
Sbjct: 3528 SALGMTAPEEDTPAPELAPEAPEPPEEPRLGVLTVTDTTPDSMRLSWSVAQGPFDSFVVQ 3587

Query: 1757 YSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAI--- 1813
            Y         L    DG++    + GL P + Y   +  LH+     PL    +T +   
Sbjct: 3588 YEDTNGQPQALLV--DGDQSKILISGLEPSTPYRFLLYGLHEGKRLGPLSAEGTTGLAPA 3645

Query: 1814 --------PAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVR--------VTPKEKTGPMK 1857
                    P  + L  T VT +SL   W  P      + +R        + P  +    +
Sbjct: 3646 GQTSEESRPRLSQLSVTDVTTSSLRLNWEAPPGAFDSFLLRFGVPSPSTLEPHPRPLLQR 3705

Query: 1858 EINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENV-SPPRRARVTDA 1916
            E+ +     S V+  L   T Y +++Y L+    +   QG   TL  V   PR  + ++ 
Sbjct: 3706 ELMVPGTRHSAVLRDLRSGTLYSLTLYGLRGPHKADSIQGTARTLSPVLESPRDLQFSEI 3765

Query: 1917 TETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYT 1976
             ET+  ++W         F+V    A+G  P    +    R+  + GL PG  Y++ + +
Sbjct: 3766 RETSAKVNWMPPPSRADSFKVSYQLADGGEPQSVQVDGQARTQKLQGLIPGARYEVTVVS 3825

Query: 1977 LNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPR 2036
            +     S P+    +T  D P+ LR L  T    ++ W+PP+  +  Y ++   PG+PP 
Sbjct: 3826 VRGFEESEPLTGFLTTVPDGPTQLRALNLTEGFAVLHWKPPQNPVDTYDVQVTAPGAPPL 3885

Query: 2037 EVVPRPRPG-VTEATITGLEPGTEYTIYVIALKNNQKSEP 2075
            +      PG   +  +  L   T YT  V  L+    + P
Sbjct: 3886 QA---ETPGSAVDYPLHDLVLHTNYTATVRGLRGPNLTSP 3922



 Score =  299 bits (766), Expect = 2e-80
 Identities = 396/1896 (20%), Positives = 691/1896 (36%), Gaps = 354/1896 (18%)

Query: 619  TPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYE 678
            T   P+S  + W  P+      ++++++ K+     +   + GH  S T+  L  G  Y 
Sbjct: 1683 TDPTPDSLRLSWTVPE-GQFDSFVVQFKDKDGP---QVVPVEGHERSVTVTPLDAGRKYR 1738

Query: 679  GQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVV 738
              L  +           D TT + S    +   TG   P  P +     VT +T +S  +
Sbjct: 1739 FLLYGLLGKKRHGPLTADGTTEARS----AMDDTGTKRPPKPRLGEELQVTTVTQNSVGL 1794

Query: 739  SWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISED-- 796
            SW         F V+Y+  +   +PQ + +  +   V++P L P  +Y + +Y +     
Sbjct: 1795 SWTVPEGQFDSFVVQYK--DRDGQPQVVPVEGSLREVSVPGLDPAHRYKLLLYGLHHGKR 1852

Query: 797  -GEQSLILST-------SQTTAPDAP-PDP-----TVDQVDDTSIVVRWSRPQAPITGYR 842
             G  S +  T       ++TTAP  P P+P     TV++    ++ + W   +     + 
Sbjct: 1853 VGPISAVAITAGREETETETTAPTPPAPEPHLGELTVEEATSHTLHLSWMVTEGEFDSFE 1912

Query: 843  IVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQET---- 898
            I Y+   +G    + +    N +TLS L+   +Y +T+Y   + +   PV ++  T    
Sbjct: 1913 IQYTDR-DGQLQMVRIGGDRNDITLSGLESDHRYLVTLYGFSDGKHVGPVHVEALTVPEE 1971

Query: 899  -------TGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRV-----DVIP--V 944
                   T TP     P   +L   + T   +++ WT PE     + V     D  P  V
Sbjct: 1972 EKPSEPPTATPEPPIKPRLGELTVTDATPDSLSLSWTVPEGQFDHFLVQYRNGDGQPKAV 2031

Query: 945  NLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPT--- 1001
             +PG H + + IS        GL P   Y   ++    G+   P++    T  +  T   
Sbjct: 2032 RVPG-HEEGVTIS--------GLEPDHKYKMNLYGFHGGQRMGPVSVVGVTAAEEETPSP 2082

Query: 1002 -----------------NLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNV 1044
                              L     +  ++ + WT P+ +   + +     R G+P+   V
Sbjct: 2083 TEPSMEAPEPAEEPLLGELTVTGSSPDSLSLSWTVPQGRFDSFTVQY-KDRDGRPQVVRV 2141

Query: 1045 GPSVSKYPLRNLQPASEYTVSLVAI-KGNQESP-KATGVFTTLQPGSSIPPYN------- 1095
            G   S+  +  L+P  +Y + L  + +G +  P  A GV    +     P          
Sbjct: 2142 GGEESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVSAVGVTAPEEESPDAPLAKLRLGQMT 2201

Query: 1096 -TEVTETTIVITWT-PAPRIG-FKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYT 1152
              ++T  ++ ++WT P  +   F +  +   G      V      + +SGL P  +Y   
Sbjct: 2202 VRDITSDSLSLSWTVPEGQFDHFLVQFKNGDGQPKAVRVPGHEDGVTISGLEPDHKYKMN 2261

Query: 1153 IQVLRDGQ----------------ERDAPIVNKVVTPLSPPTNLHLE------ANPDTGV 1190
            +     GQ                E  AP   +  TP  PP    LE      A PD+  
Sbjct: 2262 LYGFHGGQRVGPVSAVGLTAPGKDEEMAPASTEPPTP-EPPIKPRLEELTVTDATPDS-- 2318

Query: 1191 LTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTV 1250
            L++SW   T P+           NG  G      V   +   T   L P  +Y +++Y  
Sbjct: 2319 LSLSW---TVPEGQFDHFLVQYKNG-DGQPKATRVPGHEDRVTISGLEPDNKYKMNLYGF 2374

Query: 1251 KDDKESVPISDTII--------------------PEVPQLTDLSFVDITDSSIGLRWTPL 1290
               +   P+S   +                    PE P L +L+    +  S+ L WT  
Sbjct: 2375 HGGQRVGPVSAIGVTAAEEETPSPTEPSMEAPEPPEEPLLGELTVTGSSPDSLSLSWTVP 2434

Query: 1291 N---SSTIIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGES 1347
                 S  + Y+       +G P     V       TV GLEPG  Y + +  L  G   
Sbjct: 2435 QGRFDSFTVQYK-----DRDGRPQVVR-VGGEESEVTVGGLEPGRKYKMHLYGLHEGRRV 2488

Query: 1348 APTTLTQQTA-------VPPPT----------------DLRFTNIGPDTMRVTWAPPPSI 1384
             P +    TA        P PT                +L  T   PD++ ++W  P   
Sbjct: 2489 GPVSTVGVTAPQEDVDETPSPTEPGTEAPGPPEEPLLGELTVTGSSPDSLSLSWTVPQG- 2547

Query: 1385 DLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGR 1444
               +F V+Y           + +   ++ V +  L PG +Y + +  ++E     P+   
Sbjct: 2548 RFDSFTVQYKDRDGRPQA--VRVGGQESKVTVRGLEPGRKYKMHLYGLHEGRRLGPVSAV 2605

Query: 1445 QKTGLDSPT------------------GIDFSDITANSFTVHWIAPRATITGYRIRHHPE 1486
              T  ++ T                   +  +D T +S ++ W  P      + +++   
Sbjct: 2606 GVTEDEAETTQAVPTMTPEPPIKPRLGELTMTDATPDSLSLSWTVPEGQFDHFLVQY--R 2663

Query: 1487 HFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNG---------------REESPLL 1531
            +  G+P+  RVP   + +T++ L P  +Y +++   +G                EE+P  
Sbjct: 2664 NGDGQPKAVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPISVIGVTAAEEETPSP 2723

Query: 1532 IGQQSTVSDVPR-----DLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFT 1586
                +   + P      +L V  ++P SL +SW  P      + + Y +  G   V    
Sbjct: 2724 TELSTEAPEPPEEPLLGELTVTGSSPDSLSLSWTIPQGHFDSFTVQYKDRDGRPQVMR-- 2781

Query: 1587 VPGSKSTATISGLKPGVDYTITVYAV-TGRGDSPASSKPISIN-------YRTEIDKP-- 1636
            V G +S  T+ GL+PG  Y + +Y +  GR   P S+  ++ +         T   +P  
Sbjct: 2782 VRGEESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVSTVGVTEDEAETTQAVPTTTPEPPN 2841

Query: 1637 ----SQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEG 1692
                 ++ VTD   +S+S+ W+        + V    +NG G  K       +  +TI G
Sbjct: 2842 KPRLGELTVTDATPDSLSLSWMVPEGQFDHFLVQY--RNGDGQPKVVRVPGHEDGVTISG 2899

Query: 1693 LQPTVEYVVSVYAQNPSGESQPLVQTAVT------------NIDRPK--------GLAFT 1732
            L+P  +Y +++Y  +      P+    VT            + + P+         L  T
Sbjct: 2900 LEPDHKYKMNLYGFHGGQRVGPISVIGVTAAEEETPAPTEPSTEAPEPPEEPLLGELTVT 2959

Query: 1733 DVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVS 1792
                DS+ ++W  PQG+   + V Y    DG  ++     GEE    + GL PG +Y + 
Sbjct: 2960 GSSPDSLSLSWTIPQGRFDSFTVQYKD-RDGRPQVVRV-RGEESEVTVGGLEPGCKYKMH 3017

Query: 1793 VVALHDDMESQPLIGTQST----------AIPAPT----------DLKFTQVTPTSLSAQ 1832
            +  LH+     P+     T          A+P  T          +L  T  TP SLS  
Sbjct: 3018 LYGLHEGQRVGPVSAVGVTAPKDEAETTQAVPTMTPEPPIKPRLGELTVTDATPDSLSLS 3077

Query: 1833 WTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTS 1892
            W  P  Q   + V+   +   G  K + +      V +SGL    KY++++Y        
Sbjct: 3078 WMVPEGQFDHFLVQY--RNGDGQPKAVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQRV 3135

Query: 1893 RPAQGVVTTLENVSPPR----------------RARVTDATETTITISWRTKTETITGFQ 1936
             P   +  T E    P                    VT ++  ++++SW         F 
Sbjct: 3136 GPVSAIGVTEEETPSPTEPSTEAPEAPEEPLLGELTVTGSSPDSLSLSWTVPQGRFDSFT 3195

Query: 1937 VDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDA 1996
            V     +GQ  + R ++ +    T+ GL+PG  YK++LY L++  R  PV   ++  I A
Sbjct: 3196 VQYKDRDGQPQVVR-VRGEESEVTVGGLEPGRKYKMHLYGLHEGQRVGPV---STVGITA 3251

Query: 1997 P-----------SNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPG 2045
            P             L   A T +S+ +SW   +     ++++Y      P+ V   P  G
Sbjct: 3252 PLPTPLPVEPRLGELAVAAVTSDSVGLSWTVAQGPFDSFLVQYRDAQGQPQAV---PVSG 3308

Query: 2046 VTEA-TITGLEPGTEYTIYVIALKNNQ---------------KSEPLIGRKKTVQKTPFV 2089
               A  ++GL+P  +Y   +  L+N +               K  P +G       TP  
Sbjct: 3309 DLRAVAVSGLDPARKYKFLLFGLQNGKRHGPVPVEARTAPDTKPSPRLGELTVTDATPDS 3368

Query: 2090 THPGYDTGNG---------------IQLPGTSGQQPSVGQQ----------MIFEEHGFR 2124
                +    G               +Q+   +  Q  V  Q          +++   G +
Sbjct: 3369 VGLSWTVPEGEFDSFVVQYKDKDGRLQVVPVAANQREVTVQGLEPSRKYRFLLYGLSGRK 3428

Query: 2125 RTTPPTTATPIRHRPRPYPPNVG-----QEALSQTTISWAPFQDTSEYIISCHPVGTDEE 2179
            R  P +  +      +  PP++G     +E  S   +SW   Q   +  +  +   TD +
Sbjct: 3429 RLGPISADSTTAPLEKELPPHLGELTVAEETSSSLRLSWTVAQGPFDSFVVQYR-DTDGQ 3487

Query: 2180 PLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQR 2215
            P    V     + T+  L  G  Y  ++  L   +R
Sbjct: 3488 PRAVPVAADQRTVTVEDLEPGKKYKFLLYGLLGGKR 3523



 Score =  296 bits (759), Expect = 1e-79
 Identities = 409/1883 (21%), Positives = 707/1883 (37%), Gaps = 336/1883 (17%)

Query: 582  GVRYQCYCYGRGIGEWHCQPL--------QTYPSSSGPVEVF-ITETPSQPNSHPIQWNA 632
            G +Y+   YG  +G+    PL        Q+ PS   P  +  +  T   P+S  + W  
Sbjct: 1123 GRKYKFVLYGF-VGKKRHGPLVAEAKILPQSDPSPGTPPHLGNLWVTDPTPDSLHLSWTV 1181

Query: 633  PQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISI---QQYGH 689
            P+      +++++R ++  GR +   + G   S+ +  L P   Y   L  I   ++YG 
Sbjct: 1182 PE-GQFDTFMVQYRDRD--GRPQVVPVEGPERSFVVSSLDPDHKYRFTLFGIANKKRYG- 1237

Query: 690  QEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSG 749
                    T   T+ P              PL+    +VT +T  S  +SW  A      
Sbjct: 1238 ------PLTADGTTAPERKEEPPRPEFLEQPLLGEL-TVTGVTPDSLRLSWTVAQGPFDS 1290

Query: 750  FRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQI---SEDGEQSLILSTS 806
            F V+Y+  +   +PQ + +      V +P L P RKY +N+Y +      G +S++  T+
Sbjct: 1291 FMVQYK--DAQGQPQAVPVAGDENEVTVPGLDPDRKYKMNLYGLRGRQRVGPESVVAKTA 1348

Query: 807  Q--------------TTAPDAPPDPTVDQVDDT-----SIVVRWSRPQAPITGYRIVYSP 847
                           T AP++P +P + ++  T     S+ + W+ PQ     + + Y  
Sbjct: 1349 PQEDVDETPSPTELGTEAPESPEEPLLGELTVTGSSPDSLSLFWTVPQGSFDSFTVQYKD 1408

Query: 848  SVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVI-------QQETTG 900
              +G    + +    + VT+  L+PG +Y + +Y + E Q   PV         Q+ET  
Sbjct: 1409 R-DGRPRAVRVGGKESEVTVGGLEPGHKYKMHLYGLHEGQRVGPVSAVGVTAPQQEETPP 1467

Query: 901  TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNT 960
               S   P   +L   +VT   V + WT PE     +   ++         Q +P++ + 
Sbjct: 1468 ATESPLEPRLGELTVTDVTPNSVGLSWTVPEGQFDSF---IVQYKDKDGQPQVVPVAADQ 1524

Query: 961  FAEVT--GLSPGVTYYFKVFAVSHGRESKPLT------------AQQTTKLDAPTNLQFV 1006
              EVT   L P   Y   ++ +  G+   PL+            A + +K      L  +
Sbjct: 1525 -REVTVYNLEPERKYKMNMYGLHDGQRMGPLSVVIVTAPLPPAPATEASKPPLEPRLGEL 1583

Query: 1007 NETDST---VLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYT 1063
              TD T   V + WT P  +   + +     R GQP+   V     +  + +L+P+ +Y 
Sbjct: 1584 TVTDITPDSVGLSWTVPEGEFDSF-VVQYKDRDGQPQVVPVAADQREVTIPDLEPSRKYK 1642

Query: 1064 VSLVAIK-GNQESPKATGVFTTLQPGSS--IPP-----YNTEVTETTIVITWTPAPRIGF 1115
              L  I+ G + SP +    T  +  +S   PP     + T+ T  ++ ++WT  P   F
Sbjct: 1643 FLLFGIQDGKRRSPVSVEAKTVARGDASPGAPPRLGELWVTDPTPDSLRLSWT-VPEGQF 1701

Query: 1116 KLGVRPSQGGEAPR--EVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVT- 1172
               V   +  + P+   V     S+ V+ L  G +Y + +  L  G++R  P+     T 
Sbjct: 1702 DSFVVQFKDKDGPQVVPVEGHERSVTVTPLDAGRKYRFLLYGLL-GKKRHGPLTADGTTE 1760

Query: 1173 ------------PLSPPTNLHLEANPDT-GVLTVSWERSTTPD--ITGYRITTTPTNGQQ 1217
                        P  P     L+    T   + +SW   T P+     + +     +GQ 
Sbjct: 1761 ARSAMDDTGTKRPPKPRLGEELQVTTVTQNSVGLSW---TVPEGQFDSFVVQYKDRDGQ- 1816

Query: 1218 GNSLEEVVHADQS--SCTFDNLSPGLEYNVSVYTVKDDKESVPISDTII----------- 1264
                 +VV  + S    +   L P   Y + +Y +   K   PIS   I           
Sbjct: 1817 ----PQVVPVEGSLREVSVPGLDPAHRYKLLLYGLHHGKRVGPISAVAITAGREETETET 1872

Query: 1265 -------PEVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIFEDFVD 1317
                   PE P L +L+  + T  ++ L W  +       + I        + +    + 
Sbjct: 1873 TAPTPPAPE-PHLGELTVEEATSHTLHLSWM-VTEGEFDSFEIQYTDRDGQLQMVR--IG 1928

Query: 1318 SSVGYYTVTGLEPGIDYDISVITLINGGESAP------TTLTQQTAVPPPT--------- 1362
                  T++GLE    Y +++    +G    P      T   ++    PPT         
Sbjct: 1929 GDRNDITLSGLESDHRYLVTLYGFSDGKHVGPVHVEALTVPEEEKPSEPPTATPEPPIKP 1988

Query: 1363 ---DLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNL 1419
               +L  T+  PD++ ++W  P      +FLV+Y     +     + +   +  V ++ L
Sbjct: 1989 RLGELTVTDATPDSLSLSWTVPEG-QFDHFLVQYR--NGDGQPKAVRVPGHEEGVTISGL 2045

Query: 1420 LPGTEY--------------VVSVSSVYEQHESTPLRGRQKTGLDSPT------GIDFSD 1459
             P  +Y               VSV  V    E TP           P        +  + 
Sbjct: 2046 EPDHKYKMNLYGFHGGQRMGPVSVVGVTAAEEETPSPTEPSMEAPEPAEEPLLGELTVTG 2105

Query: 1460 ITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSI 1519
             + +S ++ W  P+     + +++      GRP+  RV    + +T+  L PG +Y + +
Sbjct: 2106 SSPDSLSLSWTVPQGRFDSFTVQYKDR--DGRPQVVRVGGEESEVTVGGLEPGRKYKMHL 2163

Query: 1520 VALN-GREESPL-LIGQQSTVSDVP---------RDLEVVAATPTSLLISWDAPAVTVRY 1568
              L+ GR   P+  +G  +   + P           + V   T  SL +SW  P     +
Sbjct: 2164 YGLHEGRRVGPVSAVGVTAPEEESPDAPLAKLRLGQMTVRDITSDSLSLSWTVPEGQFDH 2223

Query: 1569 YRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAV-TGRGDSPASSKPISI 1627
            + + +    G+   +   VPG +   TISGL+P   Y + +Y    G+   P S+  ++ 
Sbjct: 2224 FLVQF--KNGDGQPKAVRVPGHEDGVTISGLEPDHKYKMNLYGFHGGQRVGPVSAVGLTA 2281

Query: 1628 NYRTEIDKPS----------------QMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKN 1671
              + E   P+                ++ VTD   +S+S+ W         + V    KN
Sbjct: 2282 PGKDEEMAPASTEPPTPEPPIKPRLEELTVTDATPDSLSLSWTVPEGQFDHFLVQY--KN 2339

Query: 1672 GPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVT---------- 1721
            G G  K       +  +TI GL+P  +Y +++Y  +      P+    VT          
Sbjct: 2340 GDGQPKATRVPGHEDRVTISGLEPDNKYKMNLYGFHGGQRVGPVSAIGVTAAEEETPSPT 2399

Query: 1722 --NIDRPK--------GLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAP 1771
              +++ P+         L  T    DS+ ++W  PQG+   + V Y    DG  ++    
Sbjct: 2400 EPSMEAPEPPEEPLLGELTVTGSSPDSLSLSWTVPQGRFDSFTVQYKD-RDGRPQVVRV- 2457

Query: 1772 DGEEDTAELQGLRPGSEY-----------------TVSVVALHDDMESQPLIGTQSTAIP 1814
             GEE    + GL PG +Y                 TV V A  +D++  P      T  P
Sbjct: 2458 GGEESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVSTVGVTAPQEDVDETPSPTEPGTEAP 2517

Query: 1815 APT------DLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSV 1868
             P       +L  T  +P SLS  WT P  +   + V+   K++ G  + + +    S V
Sbjct: 2518 GPPEEPLLGELTVTGSSPDSLSLSWTVPQGRFDSFTVQY--KDRDGRPQAVRVGGQESKV 2575

Query: 1869 VVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENV-----------SPPRRAR----- 1912
             V GL    KY++ +Y L +     P   V  T +              PP + R     
Sbjct: 2576 TVRGLEPGRKYKMHLYGLHEGRRLGPVSAVGVTEDEAETTQAVPTMTPEPPIKPRLGELT 2635

Query: 1913 VTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKI 1972
            +TDAT  ++++SW         F V     +GQ    R +       TI+GL+P   YK+
Sbjct: 2636 MTDATPDSLSLSWTVPEGQFDHFLVQYRNGDGQPKAVR-VPGHEDGVTISGLEPDHKYKM 2694

Query: 1973 YLYTLNDNARSSPVVIDASTA------------IDAP--------SNLRFLATTPNSLLV 2012
             LY  +   R  P+ +   TA             +AP          L    ++P+SL +
Sbjct: 2695 NLYGFHGGQRVGPISVIGVTAAEEETPSPTELSTEAPEPPEEPLLGELTVTGSSPDSLSL 2754

Query: 2013 SWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQK 2072
            SW  P+     + ++Y+     P+  V R R   +E T+ GLEPG +Y +++  L   ++
Sbjct: 2755 SWTIPQGHFDSFTVQYKDRDGRPQ--VMRVRGEESEVTVGGLEPGRKYKMHLYGLHEGRR 2812

Query: 2073 SEPLIGRKKTVQKTPFVTHPGYDTGNGIQLPGTSGQQPSVGQQMIFEEHGFRRTTPPTTA 2132
              P+         T  VT    +T   +                            PTT 
Sbjct: 2813 VGPV--------STVGVTEDEAETTQAV----------------------------PTTT 2836

Query: 2133 TPIRHRPRPYPPNVGQEALSQTTISWAPFQDTSEYIISCHPVGTDEEPLQFRVPGTSTSA 2192
                ++PR     V        ++SW   +   ++ +  +  G D +P   RVPG     
Sbjct: 2837 PEPPNKPRLGELTVTDATPDSLSLSWMVPEGQFDHFLVQYRNG-DGQPKVVRVPGHEDGV 2895

Query: 2193 TLTGLTRGATYNIIVEALKDQQR 2215
            T++GL     Y + +      QR
Sbjct: 2896 TISGLEPDHKYKMNLYGFHGGQR 2918



 Score =  282 bits (722), Expect = 2e-75
 Identities = 383/1698 (22%), Positives = 638/1698 (37%), Gaps = 292/1698 (17%)

Query: 629  QWNAPQPSHISKYILRWRPKNSVGRWK-EATIPGHLNSYTIKGLKPGVVYEGQLISIQQY 687
            +W  P P  +  Y +++ P          A +P   ++Y  +GL PG  Y          
Sbjct: 768  EWT-PAPGPVDAYEIQFIPTTEGASPPFTARVPSSASAYDQRGLAPGQEY---------- 816

Query: 688  GHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTV 747
               +VT      TS   P +    T    P          V  +T ++  + W+     V
Sbjct: 817  ---QVTVRALRGTSWGLPASKTITTMIDGP------QDLRVVAVTPTTLELGWLRPQAEV 867

Query: 748  SGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNV---------YQIS---E 795
              F V Y     G++   L++P  A    + DL+PG +Y+V V         Y  S    
Sbjct: 868  DRFVVSY--VSAGNQRVRLEVPPEADGTLLTDLMPGVEYVVTVTAERGRAVSYPASVRAN 925

Query: 796  DGEQSL-ILSTSQTTAPDAPPD------PTVDQ------------VDDTS-IVVRWSRPQ 835
             G   L +L T+    P  P        P + Q             D+T  + V W+   
Sbjct: 926  TGSSPLGLLGTTDEPPPSGPSTTQGAQAPLLQQRPQELGELRVLGRDETGRLRVVWTAQP 985

Query: 836  APITGYRI-VYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEE-NQESTPVV 893
                 +++ +  P   G+  E+ LP       +    PG  Y ++++ V    + S P++
Sbjct: 986  DTFAYFQLRMRVPEGPGAHEEV-LPGDVRQALVPPPPPGTPYELSLHGVPPGGKPSDPII 1044

Query: 894  IQ----QETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRV-----DVIPV 944
             Q    ++     +S   P   +L   + T   + + WT PE     + +     D  P 
Sbjct: 1045 YQGIMDKDEEKPGKSSGPPRLGELTVTDRTSDSLLLRWTVPEGEFDSFVIQYKDRDGQPQ 1104

Query: 945  NLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTA------QQTTKLD 998
             +P E  QR        A +T L PG  Y F ++     +   PL A      Q      
Sbjct: 1105 VVPVEGPQR-------SAVITSLDPGRKYKFVLYGFVGKKRHGPLVAEAKILPQSDPSPG 1157

Query: 999  APT---NLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRN 1055
             P    NL   + T  ++ + WT P  Q   + +     R G+P+   V      + + +
Sbjct: 1158 TPPHLGNLWVTDPTPDSLHLSWTVPEGQFDTFMVQY-RDRDGRPQVVPVEGPERSFVVSS 1216

Query: 1056 LQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYN-------------TEVTETT 1102
            L P  +Y  +L  I   +     T   TT       PP               T VT  +
Sbjct: 1217 LDPDHKYRFTLFGIANKKRYGPLTADGTTAPERKEEPPRPEFLEQPLLGELTVTGVTPDS 1276

Query: 1103 IVITWTPA--PRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQ 1160
            + ++WT A  P   F +  + +QG      V  D   + V GL P  +Y   +  LR G+
Sbjct: 1277 LRLSWTVAQGPFDSFMVQYKDAQGQPQAVPVAGDENEVTVPGLDPDRKYKMNLYGLR-GR 1335

Query: 1161 ERDAPIVNKVVTPLSP---------PTNLHLEA-----NPDTGVLTVSWERSTTPDITGY 1206
            +R  P    VV   +P         PT L  EA      P  G LTV+    ++PD    
Sbjct: 1336 QRVGP--ESVVAKTAPQEDVDETPSPTELGTEAPESPEEPLLGELTVT---GSSPDSLSL 1390

Query: 1207 RIT---------TTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESV 1257
              T         T     + G      V   +S  T   L PG +Y + +Y + + +   
Sbjct: 1391 FWTVPQGSFDSFTVQYKDRDGRPRAVRVGGKESEVTVGGLEPGHKYKMHLYGLHEGQRVG 1450

Query: 1258 PIS--------------DTIIPEVPQLTDLSFVDITDSSIGLRWTPLN---SSTIIGYRI 1300
            P+S               T  P  P+L +L+  D+T +S+GL WT       S I+ Y+ 
Sbjct: 1451 PVSAVGVTAPQQEETPPATESPLEPRLGELTVTDVTPNSVGLSWTVPEGQFDSFIVQYK- 1509

Query: 1301 TVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAVPP 1360
                  + +P+  D  +      TV  LEP   Y +++  L +G    P ++   TA  P
Sbjct: 1510 DKDGQPQVVPVAADQRE-----VTVYNLEPERKYKMNMYGLHDGQRMGPLSVVIVTAPLP 1564

Query: 1361 PT---------------DLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAEL 1405
            P                +L  T+I PD++ ++W  P   +  +F+V+Y     +  V  +
Sbjct: 1565 PAPATEASKPPLEPRLGELTVTDITPDSVGLSWTVPEG-EFDSFVVQYKDRDGQPQV--V 1621

Query: 1406 SISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKT---GLDSPTG------ID 1456
             ++     V + +L P  +Y   +  + +    +P+    KT   G  SP        + 
Sbjct: 1622 PVAADQREVTIPDLEPSRKYKFLLFGIQDGKRRSPVSVEAKTVARGDASPGAPPRLGELW 1681

Query: 1457 FSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYV 1516
             +D T +S  + W  P      + ++   +     P+   V     S+T+T L  G +Y 
Sbjct: 1682 VTDPTPDSLRLSWTVPEGQFDSFVVQFKDK---DGPQVVPVEGHERSVTVTPLDAGRKYR 1738

Query: 1517 VSIVALNGREESPLLIGQ-----QSTVSDV-------PR---DLEVVAATPTSLLISWDA 1561
              +  L G++    L        +S + D        PR   +L+V   T  S+ +SW  
Sbjct: 1739 FLLYGLLGKKRHGPLTADGTTEARSAMDDTGTKRPPKPRLGEELQVTTVTQNSVGLSWTV 1798

Query: 1562 PAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAV-TGRGDSPA 1620
            P      + + Y +  G    Q   V GS    ++ GL P   Y + +Y +  G+   P 
Sbjct: 1799 PEGQFDSFVVQYKDRDGQP--QVVPVEGSLREVSVPGLDPAHRYKLLLYGLHHGKRVGPI 1856

Query: 1621 SSKPISI---NYRTEIDKPS---------QMQVTDVQDNSISVKWLPSSSPVTGYRVTTT 1668
            S+  I+       TE   P+         ++ V +   +++ + W+ +      + +  T
Sbjct: 1857 SAVAITAGREETETETTAPTPPAPEPHLGELTVEEATSHTLHLSWMVTEGEFDSFEIQYT 1916

Query: 1669 PKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPK- 1727
             ++  G  +    G D+ ++T+ GL+    Y+V++Y  +      P+   A+T  +  K 
Sbjct: 1917 DRD--GQLQMVRIGGDRNDITLSGLESDHRYLVTLYGFSDGKHVGPVHVEALTVPEEEKP 1974

Query: 1728 -----------------GLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPA 1770
                              L  TD   DS+ ++W  P+GQ   + V Y +  DG  +    
Sbjct: 1975 SEPPTATPEPPIKPRLGELTVTDATPDSLSLSWTVPEGQFDHFLVQYRN-GDGQPKAVRV 2033

Query: 1771 PDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTA----IPAPT--------- 1817
            P G E+   + GL P  +Y +++   H      P+     TA     P+PT         
Sbjct: 2034 P-GHEEGVTISGLEPDHKYKMNLYGFHGGQRMGPVSVVGVTAAEEETPSPTEPSMEAPEP 2092

Query: 1818 -------DLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVV 1870
                   +L  T  +P SLS  WT P  +   + V+   K++ G  + + +  + S V V
Sbjct: 2093 AEEPLLGELTVTGSSPDSLSLSWTVPQGRFDSFTVQY--KDRDGRPQVVRVGGEESEVTV 2150

Query: 1871 SGLMVATKYEVSVYALKDTLTSRPAQGV-VTTLENVSPPR--------RARVTDATETTI 1921
             GL    KY++ +Y L +     P   V VT  E  SP          +  V D T  ++
Sbjct: 2151 GGLEPGRKYKMHLYGLHEGRRVGPVSAVGVTAPEEESPDAPLAKLRLGQMTVRDITSDSL 2210

Query: 1922 TISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNA 1981
            ++SW         F V     +GQ    R +       TI+GL+P   YK+ LY  +   
Sbjct: 2211 SLSWTVPEGQFDHFLVQFKNGDGQPKAVR-VPGHEDGVTISGLEPDHKYKMNLYGFHGGQ 2269

Query: 1982 RSSPV-------------VIDASTAIDAP--------SNLRFLATTPNSLLVSWQPPRAR 2020
            R  PV             +  AST    P          L     TP+SL +SW  P  +
Sbjct: 2270 RVGPVSAVGLTAPGKDEEMAPASTEPPTPEPPIKPRLEELTVTDATPDSLSLSWTVPEGQ 2329

Query: 2021 ITGYIIKYEK-PGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPL--I 2077
               ++++Y+   G P    VP     V   TI+GLEP  +Y + +      Q+  P+  I
Sbjct: 2330 FDHFLVQYKNGDGQPKATRVPGHEDRV---TISGLEPDNKYKMNLYGFHGGQRVGPVSAI 2386

Query: 2078 GRKKTVQKTPFVTHPGYD 2095
            G     ++TP  T P  +
Sbjct: 2387 GVTAAEEETPSPTEPSME 2404



 Score =  278 bits (712), Expect = 4e-74
 Identities = 379/1680 (22%), Positives = 631/1680 (37%), Gaps = 273/1680 (16%)

Query: 740  WVSASDTVSGFRVEYELSEEGDEPQYLD-LPSTATSVNIPDLLPGRKYIVNVYQISEDGE 798
            W  A   V  + +++  + EG  P +   +PS+A++ +   L PG++Y V V  +     
Sbjct: 769  WTPAPGPVDAYEIQFIPTTEGASPPFTARVPSSASAYDQRGLAPGQEYQVTVRAL-RGTS 827

Query: 799  QSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNL 858
              L  S + TT  D P D  V  V  T++ + W RPQA +  + + Y  S       L +
Sbjct: 828  WGLPASKTITTMIDGPQDLRVVAVTPTTLELGWLRPQAEVDRFVVSYV-SAGNQRVRLEV 886

Query: 859  PETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTP------RSDTVPS--- 909
            P  A+   L+DL PGV+Y +T+ A      S P  ++  T  +P        +  PS   
Sbjct: 887  PPEADGTLLTDLMPGVEYVVTVTAERGRAVSYPASVRANTGSSPLGLLGTTDEPPPSGPS 946

Query: 910  -------------PRDLQFVEVTDVKVT----IMWTPPESAVTGYRVDVIPVNLPGEHGQ 952
                         P++L  + V     T    ++WT        +++ +     PG H +
Sbjct: 947  TTQGAQAPLLQQRPQELGELRVLGRDETGRLRVVWTAQPDTFAYFQLRMRVPEGPGAHEE 1006

Query: 953  RLPISRNTFAEVTGLSPGVTYYFKVFAVSHG-RESKPLTAQ--------QTTKLDAPTNL 1003
             LP      A V    PG  Y   +  V  G + S P+  Q        +  K   P  L
Sbjct: 1007 VLPGDVRQ-ALVPPPPPGTPYELSLHGVPPGGKPSDPIIYQGIMDKDEEKPGKSSGPPRL 1065

Query: 1004 QFVNETDST---VLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPAS 1060
              +  TD T   +L+RWT P  +   + +     R GQP+   V        + +L P  
Sbjct: 1066 GELTVTDRTSDSLLLRWTVPEGEFDSFVIQYK-DRDGQPQVVPVEGPQRSAVITSLDPGR 1124

Query: 1061 EYTVSLVAIKGNQESPKATG---VFTTLQPGSSIPPYN-----TEVTETTIVITWT-PAP 1111
            +Y   L    G +          +     P    PP+      T+ T  ++ ++WT P  
Sbjct: 1125 KYKFVLYGFVGKKRHGPLVAEAKILPQSDPSPGTPPHLGNLWVTDPTPDSLHLSWTVPEG 1184

Query: 1112 RIG-FKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKV 1170
            +   F +  R   G      V     S VVS L P  +Y +T+  + + ++R  P+    
Sbjct: 1185 QFDTFMVQYRDRDGRPQVVPVEGPERSFVVSSLDPDHKYRFTLFGIAN-KKRYGPLTADG 1243

Query: 1171 VTPLS----PPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQ---------- 1216
             T       PP    LE  P  G LTV+     TPD    R++ T   G           
Sbjct: 1244 TTAPERKEEPPRPEFLE-QPLLGELTVT---GVTPD--SLRLSWTVAQGPFDSFMVQYKD 1297

Query: 1217 -QGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVK-----------------DDKESVP 1258
             QG      V  D++  T   L P  +Y +++Y ++                 +D +  P
Sbjct: 1298 AQGQPQAVPVAGDENEVTVPGLDPDRKYKMNLYGLRGRQRVGPESVVAKTAPQEDVDETP 1357

Query: 1259 ISDTI------IPEVPQLTDLSFVDITDSSIGLRWT-PLNS--STIIGYRITVVAAGEGI 1309
                +       PE P L +L+    +  S+ L WT P  S  S  + Y+       +G 
Sbjct: 1358 SPTELGTEAPESPEEPLLGELTVTGSSPDSLSLFWTVPQGSFDSFTVQYKDR-----DGR 1412

Query: 1310 PIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPT-----TLTQQTAVPPPTD- 1363
            P     V       TV GLEPG  Y + +  L  G    P      T  QQ   PP T+ 
Sbjct: 1413 PRAVR-VGGKESEVTVGGLEPGHKYKMHLYGLHEGQRVGPVSAVGVTAPQQEETPPATES 1471

Query: 1364 --------LRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVV 1415
                    L  T++ P+++ ++W  P      +F+V+Y     +  V  + ++     V 
Sbjct: 1472 PLEPRLGELTVTDVTPNSVGLSWTVPEG-QFDSFIVQYKDKDGQPQV--VPVAADQREVT 1528

Query: 1416 LTNLLPGTEYVVSVSSVYEQHESTPLR--------------GRQKTGLDSPTG-IDFSDI 1460
            + NL P  +Y +++  +++     PL                  K  L+   G +  +DI
Sbjct: 1529 VYNLEPERKYKMNMYGLHDGQRMGPLSVVIVTAPLPPAPATEASKPPLEPRLGELTVTDI 1588

Query: 1461 TANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIV 1520
            T +S  + W  P      + +++      G+P+   V   +  +T+ +L P  +Y   + 
Sbjct: 1589 TPDSVGLSWTVPEGEFDSFVVQYKDR--DGQPQVVPVAADQREVTIPDLEPSRKYKFLLF 1646

Query: 1521 AL-NGREESPLLIGQQSTVSD------VPR--DLEVVAATPTSLLISWDAPAVTVRYYRI 1571
             + +G+  SP+ +  ++           PR  +L V   TP SL +SW  P      + +
Sbjct: 1647 GIQDGKRRSPVSVEAKTVARGDASPGAPPRLGELWVTDPTPDSLRLSWTVPEGQFDSFVV 1706

Query: 1572 TYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRT 1631
             + +  G   V    V G + + T++ L  G  Y   +Y + G+      +   +   R+
Sbjct: 1707 QFKDKDGPQVVP---VEGHERSVTVTPLDAGRKYRFLLYGLLGKKRHGPLTADGTTEARS 1763

Query: 1632 EID--------KP---SQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKT 1680
             +D        KP    ++QVT V  NS+ + W         + V    ++G  P     
Sbjct: 1764 AMDDTGTKRPPKPRLGEELQVTTVTQNSVGLSWTVPEGQFDSFVVQYKDRDGQ-PQVVPV 1822

Query: 1681 AGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVT----------NIDRPKG-- 1728
             G    E+++ GL P   Y + +Y  +      P+   A+T              P    
Sbjct: 1823 EG-SLREVSVPGLDPAHRYKLLLYGLHHGKRVGPISAVAITAGREETETETTAPTPPAPE 1881

Query: 1729 -----LAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGL 1783
                 L   +    ++ ++W   +G+   + + Y+   DG  ++     G+ +   L GL
Sbjct: 1882 PHLGELTVEEATSHTLHLSWMVTEGEFDSFEIQYTD-RDGQLQMVRI-GGDRNDITLSGL 1939

Query: 1784 RPGSEYTVSVVALHDDMESQPLI------------GTQSTAIPAPT------DLKFTQVT 1825
                 Y V++    D     P+                 TA P P       +L  T  T
Sbjct: 1940 ESDHRYLVTLYGFSDGKHVGPVHVEALTVPEEEKPSEPPTATPEPPIKPRLGELTVTDAT 1999

Query: 1826 PTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYA 1885
            P SLS  WT P  Q   + V+   +   G  K + +      V +SGL    KY++++Y 
Sbjct: 2000 PDSLSLSWTVPEGQFDHFLVQY--RNGDGQPKAVRVPGHEEGVTISGLEPDHKYKMNLYG 2057

Query: 1886 LKDTLTSRPAQGV-VTTLENVSP---------PRRAR--------VTDATETTITISWRT 1927
                    P   V VT  E  +P         P  A         VT ++  ++++SW  
Sbjct: 2058 FHGGQRMGPVSVVGVTAAEEETPSPTEPSMEAPEPAEEPLLGELTVTGSSPDSLSLSWTV 2117

Query: 1928 KTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVV 1987
                   F V     +G+  + R +  +    T+ GL+PG  YK++LY L++  R  PV 
Sbjct: 2118 PQGRFDSFTVQYKDRDGRPQVVR-VGGEESEVTVGGLEPGRKYKMHLYGLHEGRRVGPVS 2176

Query: 1988 IDASTA-----IDAP------SNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPR 2036
                TA      DAP        +     T +SL +SW  P  +   ++++++     P+
Sbjct: 2177 AVGVTAPEEESPDAPLAKLRLGQMTVRDITSDSLSLSWTVPEGQFDHFLVQFKNGDGQPK 2236

Query: 2037 EV-VPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQKTPFVTHPGYD 2095
             V VP    GV   TI+GLEP  +Y + +      Q+  P+            +T PG D
Sbjct: 2237 AVRVPGHEDGV---TISGLEPDHKYKMNLYGFHGGQRVGPV--------SAVGLTAPGKD 2285

Query: 2096 TGNGIQLPGTSGQQPSVGQQMIFEEHGFRRTTPPTTATPIRHRPRPYPPNVGQEALSQTT 2155
                                   EE     T PPT   PI  +PR     V        +
Sbjct: 2286 -----------------------EEMAPASTEPPTPEPPI--KPRLEELTVTDATPDSLS 2320

Query: 2156 ISWAPFQDTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQR 2215
            +SW   +   ++ +  +  G D +P   RVPG     T++GL     Y + +      QR
Sbjct: 2321 LSWTVPEGQFDHFLVQYKNG-DGQPKATRVPGHEDRVTISGLEPDNKYKMNLYGFHGGQR 2379



 Score =  234 bits (598), Expect = 6e-61
 Identities = 308/1385 (22%), Positives = 514/1385 (37%), Gaps = 211/1385 (15%)

Query: 900  GTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGE--HGQRLPIS 957
            G    + VP+   ++   + +  V   WTP    V  Y +  IP           R+P S
Sbjct: 742  GEDCGEEVPTIEGMRMHLLEETTVRTEWTPAPGPVDAYEIQFIPTTEGASPPFTARVPSS 801

Query: 958  RNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRW 1017
             + + +  GL+PG  Y   V A+       P +   TT +D P +L+ V  T +T+ + W
Sbjct: 802  ASAYDQ-RGLAPGQEYQVTVRALRGTSWGLPASKTITTMIDGPQDLRVVAVTPTTLELGW 860

Query: 1018 TPPRAQITGYRLTVGLTRRGQPR-QYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESP 1076
              P+A++   R  V     G  R +  V P      L +L P  EY V++ A +G   S 
Sbjct: 861  LRPQAEVD--RFVVSYVSAGNQRVRLEVPPEADGTLLTDLMPGVEYVVTVTAERGRAVSY 918

Query: 1077 KAT----------GVFTTLQPGSSIPPYNTEVTETTIV---------------------- 1104
             A+          G+  T        P  T+  +  ++                      
Sbjct: 919  PASVRANTGSSPLGLLGTTDEPPPSGPSTTQGAQAPLLQQRPQELGELRVLGRDETGRLR 978

Query: 1105 ITWTPAPR--IGFKLGVRPSQGGEAPREV-TSDSGSIVVSGLTPGVEYVYTIQVLRDGQE 1161
            + WT  P     F+L +R  +G  A  EV   D    +V    PG  Y  ++  +  G +
Sbjct: 979  VVWTAQPDTFAYFQLRMRVPEGPGAHEEVLPGDVRQALVPPPPPGTPYELSLHGVPPGGK 1038

Query: 1162 RDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERS-------TTPDITGYRITTTPTN 1214
               PI+ + +              P  G LTV+   S       T P+   +        
Sbjct: 1039 PSDPIIYQGIMDKDEEKPGKSSGPPRLGELTVTDRTSDSLLLRWTVPE-GEFDSFVIQYK 1097

Query: 1215 GQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPI---------SDTIIP 1265
             + G      V   Q S    +L PG +Y   +Y     K   P+         SD    
Sbjct: 1098 DRDGQPQVVPVEGPQRSAVITSLDPGRKYKFVLYGFVGKKRHGPLVAEAKILPQSDPSPG 1157

Query: 1266 EVPQLTDLSFVDITDSSIGLRWTPLN---SSTIIGYRITVVAAGEGIPIFEDFVDSSVGY 1322
              P L +L   D T  S+ L WT       + ++ YR       +G P     V+     
Sbjct: 1158 TPPHLGNLWVTDPTPDSLHLSWTVPEGQFDTFMVQYR-----DRDGRPQVVP-VEGPERS 1211

Query: 1323 YTVTGLEPGIDYDISVITLINGGESAPTTLTQQTA----VPPPT----------DLRFTN 1368
            + V+ L+P   Y  ++  + N     P T    TA      PP           +L  T 
Sbjct: 1212 FVVSSLDPDHKYRFTLFGIANKKRYGPLTADGTTAPERKEEPPRPEFLEQPLLGELTVTG 1271

Query: 1369 IGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLP------- 1421
            + PD++R++W         +F+V+Y   + +     + ++  +N V +  L P       
Sbjct: 1272 VTPDSLRLSWTVAQG-PFDSFMVQYKDAQGQPQA--VPVAGDENEVTVPGLDPDRKYKMN 1328

Query: 1422 ----------GTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTG--------IDFSDITAN 1463
                      G E VV+ ++  E  + TP     + G ++P          +  +  + +
Sbjct: 1329 LYGLRGRQRVGPESVVAKTAPQEDVDETP--SPTELGTEAPESPEEPLLGELTVTGSSPD 1386

Query: 1464 SFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEY-------- 1515
            S ++ W  P+ +   + +++      GRPR  RV    + +T+  L PG +Y        
Sbjct: 1387 SLSLFWTVPQGSFDSFTVQYKDR--DGRPRAVRVGGKESEVTVGGLEPGHKYKMHLYGLH 1444

Query: 1516 ------VVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYY 1569
                   VS V +   ++       +S +     +L V   TP S+ +SW  P      +
Sbjct: 1445 EGQRVGPVSAVGVTAPQQEETPPATESPLEPRLGELTVTDVTPNSVGLSWTVPEGQFDSF 1504

Query: 1570 RITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAV-TGRGDSPAS----SKP 1624
             + Y +  G    Q   V   +   T+  L+P   Y + +Y +  G+   P S    + P
Sbjct: 1505 IVQYKDKDGQP--QVVPVAADQREVTVYNLEPERKYKMNMYGLHDGQRMGPLSVVIVTAP 1562

Query: 1625 ISINYRTEIDKP------SQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKT 1678
            +     TE  KP       ++ VTD+  +S+ + W         + V    K+  G  + 
Sbjct: 1563 LPPAPATEASKPPLEPRLGELTVTDITPDSVGLSWTVPEGEFDSFVVQY--KDRDGQPQV 1620

Query: 1679 KTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTA--VTNIDRPKG-------L 1729
                 DQ E+TI  L+P+ +Y   ++         P+   A  V   D   G       L
Sbjct: 1621 VPVAADQREVTIPDLEPSRKYKFLLFGIQDGKRRSPVSVEAKTVARGDASPGAPPRLGEL 1680

Query: 1730 AFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEY 1789
              TD   DS++++W  P+GQ   + V +   +DG  ++ P  +G E +  +  L  G +Y
Sbjct: 1681 WVTDPTPDSLRLSWTVPEGQFDSFVVQFKD-KDG-PQVVPV-EGHERSVTVTPLDAGRKY 1737

Query: 1790 TVSVVALHDDMESQPLIGTQSTAI------------PAP---TDLKFTQVTPTSLSAQWT 1834
               +  L       PL    +T              P P    +L+ T VT  S+   WT
Sbjct: 1738 RFLLYGLLGKKRHGPLTADGTTEARSAMDDTGTKRPPKPRLGEELQVTTVTQNSVGLSWT 1797

Query: 1835 PPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRP 1894
             P  Q   + V+   K++ G  + + +      V V GL  A +Y++ +Y L       P
Sbjct: 1798 VPEGQFDSFVVQY--KDRDGQPQVVPVEGSLREVSVPGLDPAHRYKLLLYGLHHGKRVGP 1855

Query: 1895 AQGVV-------TTLENVSPPRRA--------RVTDATETTITISWRTKTETITGFQVDA 1939
               V        T  E  +P   A         V +AT  T+ +SW         F++  
Sbjct: 1856 ISAVAITAGREETETETTAPTPPAPEPHLGELTVEEATSHTLHLSWMVTEGEFDSFEIQY 1915

Query: 1940 VPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDA--------- 1990
               +GQ  + R I  D    T++GL+    Y + LY  +D     PV ++A         
Sbjct: 1916 TDRDGQLQMVR-IGGDRNDITLSGLESDHRYLVTLYGFSDGKHVGPVHVEALTVPEEEKP 1974

Query: 1991 ---STAIDAP------SNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREV-VP 2040
                TA   P        L     TP+SL +SW  P  +   ++++Y      P+ V VP
Sbjct: 1975 SEPPTATPEPPIKPRLGELTVTDATPDSLSLSWTVPEGQFDHFLVQYRNGDGQPKAVRVP 2034

Query: 2041 RPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEP--LIGRKKTVQKTPFVTHPGYDTGN 2098
                GV   TI+GLEP  +Y + +      Q+  P  ++G     ++TP  T P  +   
Sbjct: 2035 GHEEGV---TISGLEPDHKYKMNLYGFHGGQRMGPVSVVGVTAAEEETPSPTEPSMEAPE 2091

Query: 2099 GIQLP 2103
              + P
Sbjct: 2092 PAEEP 2096



 Score =  206 bits (523), Expect = 3e-52
 Identities = 259/1075 (24%), Positives = 406/1075 (37%), Gaps = 178/1075 (16%)

Query: 1192 TVSWERSTTPD-ITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDN--LSPGLEYNVSVY 1248
            TV  E +  P  +  Y I   PT   +G S         S+  +D   L+PG EY V+V 
Sbjct: 764  TVRTEWTPAPGPVDAYEIQFIPTT--EGASPPFTARVPSSASAYDQRGLAPGQEYQVTVR 821

Query: 1249 TVKDDKESVPISDTIIPEVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGEG 1308
             ++     +P S TI   +    DL  V +T +++ L W    +  +  + ++ V+AG  
Sbjct: 822  ALRGTSWGLPASKTITTMIDGPQDLRVVAVTPTTLELGWLRPQAE-VDRFVVSYVSAGNQ 880

Query: 1309 IPIFEDFVDSSVGYYTVTGLEPGIDYDISVIT------------LINGGESAPTTLTQQT 1356
                E  V        +T L PG++Y ++V                N G S+P  L   T
Sbjct: 881  RVRLE--VPPEADGTLLTDLMPGVEYVVTVTAERGRAVSYPASVRANTG-SSPLGLLGTT 937

Query: 1357 AVPPPTDLRFTN-------------------IGPDT---MRVTWAPPPSIDLTNFLVRY- 1393
              PPP+    T                    +G D    +RV W   P      F +R  
Sbjct: 938  DEPPPSGPSTTQGAQAPLLQQRPQELGELRVLGRDETGRLRVVWTAQPDT-FAYFQLRMR 996

Query: 1394 ---SPVKNEE----DVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHE-STPL---- 1441
                P  +EE    DV +  + P           PGT Y +S+  V    + S P+    
Sbjct: 997  VPEGPGAHEEVLPGDVRQALVPPPP---------PGTPYELSLHGVPPGGKPSDPIIYQG 1047

Query: 1442 ---RGRQKTGLDSPTG----IDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPRE 1494
               +  +K G  S       +  +D T++S  + W  P      + I++      G+P+ 
Sbjct: 1048 IMDKDEEKPGKSSGPPRLGELTVTDRTSDSLLLRWTVPEGEFDSFVIQYKDR--DGQPQV 1105

Query: 1495 DRVPHSRNSITLTNLTPGTEYVVSIVALNGRE-------ESPLLIGQQSTVSDVPR--DL 1545
              V   + S  +T+L PG +Y   +    G++       E+ +L     +    P   +L
Sbjct: 1106 VPVEGPQRSAVITSLDPGRKYKFVLYGFVGKKRHGPLVAEAKILPQSDPSPGTPPHLGNL 1165

Query: 1546 EVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDY 1605
             V   TP SL +SW  P      + + Y +  G   V    V G + +  +S L P   Y
Sbjct: 1166 WVTDPTPDSLHLSWTVPEGQFDTFMVQYRDRDGRPQV--VPVEGPERSFVVSSLDPDHKY 1223

Query: 1606 TITVYAVTGRGD-SPASSKPISINYRTE-------IDKP--SQMQVTDVQDNSISVKWLP 1655
              T++ +  +    P ++   +   R E       +++P   ++ VT V  +S+ + W  
Sbjct: 1224 RFTLFGIANKKRYGPLTADGTTAPERKEEPPRPEFLEQPLLGELTVTGVTPDSLRLSWTV 1283

Query: 1656 SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYA----QNPSGE 1711
            +  P   + V      G  P     AG D+ E+T+ GL P  +Y +++Y     Q    E
Sbjct: 1284 AQGPFDSFMVQYKDAQGQ-PQAVPVAG-DENEVTVPGLDPDRKYKMNLYGLRGRQRVGPE 1341

Query: 1712 SQPLVQTAVTNIDRPKG-------------------LAFTDVDVDSIKIAWESPQGQVSR 1752
            S         ++D                       L  T    DS+ + W  PQG    
Sbjct: 1342 SVVAKTAPQEDVDETPSPTELGTEAPESPEEPLLGELTVTGSSPDSLSLFWTVPQGSFDS 1401

Query: 1753 YRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIG----- 1807
            + V Y    DG         G+E    + GL PG +Y + +  LH+     P+       
Sbjct: 1402 FTVQYKD-RDGRPRAVRV-GGKESEVTVGGLEPGHKYKMHLYGLHEGQRVGPVSAVGVTA 1459

Query: 1808 ---------TQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKE 1858
                     T+S   P   +L  T VTP S+   WT P  Q   + V+   K+K G  + 
Sbjct: 1460 PQQEETPPATESPLEPRLGELTVTDVTPNSVGLSWTVPEGQFDSFIVQY--KDKDGQPQV 1517

Query: 1859 INLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTL--------ENVSPPRR 1910
            + +A D   V V  L    KY++++Y L D     P   V+ T         E   PP  
Sbjct: 1518 VPVAADQREVTVYNLEPERKYKMNMYGLHDGQRMGPLSVVIVTAPLPPAPATEASKPPLE 1577

Query: 1911 AR-----VTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQ 1965
             R     VTD T  ++ +SW         F V     +GQ  +   +  D R  TI  L+
Sbjct: 1578 PRLGELTVTDITPDSVGLSWTVPEGEFDSFVVQYKDRDGQPQVV-PVAADQREVTIPDLE 1636

Query: 1966 PGTDYKIYLYTLNDNARSSPVVIDASTAI------DAPSNLRFL---ATTPNSLLVSWQP 2016
            P   YK  L+ + D  R SPV ++A T         AP  L  L     TP+SL +SW  
Sbjct: 1637 PSRKYKFLLFGIQDGKRRSPVSVEAKTVARGDASPGAPPRLGELWVTDPTPDSLRLSWTV 1696

Query: 2017 PRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPL 2076
            P  +   ++++++    P  +VVP         T+T L+ G +Y   +  L   ++  PL
Sbjct: 1697 PEGQFDSFVVQFKDKDGP--QVVP-VEGHERSVTVTPLDAGRKYRFLLYGLLGKKRHGPL 1753

Query: 2077 IGRKKTVQKTPFVTHPGYDTGN--------GIQLPGTSGQQPSVGQQMIFEEHGF 2123
                 T   T        DTG         G +L  T+  Q SVG      E  F
Sbjct: 1754 -----TADGTTEARSAMDDTGTKRPPKPRLGEELQVTTVTQNSVGLSWTVPEGQF 1803



 Score =  103 bits (257), Expect = 2e-21
 Identities = 100/428 (23%), Positives = 166/428 (38%), Gaps = 60/428 (14%)

Query: 1704 YAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDG 1763
            YA    GE  P ++          G+    ++  +++  W    G V  Y + +    +G
Sbjct: 740  YAGEDCGEEVPTIE----------GMRMHLLEETTVRTEWTPAPGPVDAYEIQFIPTTEG 789

Query: 1764 IHELFPAPDGEEDTA-ELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFT 1822
                F A      +A + +GL PG EY V+V AL       P   T +T I  P DL+  
Sbjct: 790  ASPPFTARVPSSASAYDQRGLAPGQEYQVTVRALRGTSWGLPASKTITTMIDGPQDLRVV 849

Query: 1823 QVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVS 1882
             VTPT+L   W  P  ++   R  V+          + + P++   +++ LM   +Y V+
Sbjct: 850  AVTPTTLELGWLRPQAEVD--RFVVSYVSAGNQRVRLEVPPEADGTLLTDLMPGVEYVVT 907

Query: 1883 VYALKDTLTSRPAQ----------GVVTTLENVSPP--------------------RRAR 1912
            V A +    S PA           G++ T +   P                        R
Sbjct: 908  VTAERGRAVSYPASVRANTGSSPLGLLGTTDEPPPSGPSTTQGAQAPLLQQRPQELGELR 967

Query: 1913 VTDATET-TITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYK 1971
            V    ET  + + W  + +T   FQ+      G    +  +  DVR   +    PGT Y+
Sbjct: 968  VLGRDETGRLRVVWTAQPDTFAYFQLRMRVPEGPGAHEEVLPGDVRQALVPPPPPGTPYE 1027

Query: 1972 IYLYTLNDNAR-SSPVVIDASTAID--------APSNLRFLAT---TPNSLLVSWQPPRA 2019
            + L+ +    + S P++       D         P  L  L     T +SLL+ W  P  
Sbjct: 1028 LSLHGVPPGGKPSDPIIYQGIMDKDEEKPGKSSGPPRLGELTVTDRTSDSLLLRWTVPEG 1087

Query: 2020 RITGYIIKY-EKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIG 2078
                ++I+Y ++ G P  +VVP   P    A IT L+PG +Y   +      ++  PL+ 
Sbjct: 1088 EFDSFVIQYKDRDGQP--QVVPVEGP-QRSAVITSLDPGRKYKFVLYGFVGKKRHGPLVA 1144

Query: 2079 RKKTVQKT 2086
              K + ++
Sbjct: 1145 EAKILPQS 1152



 Score = 78.6 bits (192), Expect = 7e-14
 Identities = 74/319 (23%), Positives = 120/319 (37%), Gaps = 44/319 (13%)

Query: 1918 ETTITISWRTKTETITGFQVDAVPAN--GQTPIQRTIKPDVRSYTITGLQPGTDYKIYLY 1975
            ETT+   W      +  +++  +P       P    +     +Y   GL PG +Y++ + 
Sbjct: 762  ETTVRTEWTPAPGPVDAYEIQFIPTTEGASPPFTARVPSSASAYDQRGLAPGQEYQVTVR 821

Query: 1976 TLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPP 2035
             L   +   P     +T ID P +LR +A TP +L + W  P+A +  +++ Y   G+  
Sbjct: 822  ALRGTSWGLPASKTITTMIDGPQDLRVVAVTPTTLELGWLRPQAEVDRFVVSYVSAGN-- 879

Query: 2036 REVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQKTPFVTHPGYD 2095
            + V     P      +T L PG EY + V A +    S P   R  T             
Sbjct: 880  QRVRLEVPPEADGTLLTDLMPGVEYVVTVTAERGRAVSYPASVRANT------------- 926

Query: 2096 TGNGIQLPGTSGQQPSVGQQMIFEEHGFRRTTPPTTATPIRHRPRPYPP--NVGQEALSQ 2153
              + + L GT+ + P  G            TT    A  ++ RP+       +G++   +
Sbjct: 927  GSSPLGLLGTTDEPPPSGPS----------TTQGAQAPLLQQRPQELGELRVLGRDETGR 976

Query: 2154 TTISWAPFQDTSEYIISCHPV----GTDEEPLQFRV---------PGTSTSATLTGLTRG 2200
              + W    DT  Y      V    G  EE L   V         PGT    +L G+  G
Sbjct: 977  LRVVWTAQPDTFAYFQLRMRVPEGPGAHEEVLPGDVRQALVPPPPPGTPYELSLHGVPPG 1036

Query: 2201 ATYN--IIVEALKDQQRHK 2217
               +  II + + D+   K
Sbjct: 1037 GKPSDPIIYQGIMDKDEEK 1055


>gi|93141049 collagen, type XII, alpha 1 short isoform precursor [Homo
            sapiens]
          Length = 1899

 Score =  291 bits (744), Expect = 7e-78
 Identities = 256/956 (26%), Positives = 430/956 (44%), Gaps = 58/956 (6%)

Query: 1166 IVNKVVTP--LSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEE 1223
            + N V  P  L  P+NL +          VSW    +  +  Y++   P +G  G   E 
Sbjct: 211  LCNSVKGPGDLEAPSNLVISERTHRS-FRVSWT-PPSDSVDRYKVEYYPVSG--GKRQEF 266

Query: 1224 VVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPEVPQLTDLSFVDITDSSI 1283
             V   ++S    +L P  EY V+VY+V +D+ S P+  T       +  L+  D+  +++
Sbjct: 267  YVSRMETSTVLKDLKPETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVVSLNIYDVGPTTM 326

Query: 1284 GLRWTPLNSSTIIGYRITVVAAGEGIPIF--EDFVDSSVGYYTVTGLEPGIDYDISVITL 1341
             ++W P+  +T  GY ++     +  P    E  +  +V    +T L P  +Y ++V  +
Sbjct: 327  HVQWQPVGGAT--GYILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAV 384

Query: 1342 INGGESAPTTLTQQTA-VPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEE 1400
            ++   S P T+ + T  +P P DL+  ++   TM V W P P   +  ++VRY     EE
Sbjct: 385  LHDLTSEPVTVREVTLPLPRPQDLKLRDVTHSTMNVFWEPVPG-KVRKYIVRYKTP--EE 441

Query: 1401 DVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTG-LDSPTGIDFSD 1459
            DV E+ +  S+ +  L +L   T Y VSVS+V+++ ES P+  ++ T  + +PT +  ++
Sbjct: 442  DVKEVEVDRSETSTSLKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPAPTNLKITE 501

Query: 1460 ITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSI 1519
            +T+  F   W    + ++ YRI   P   S +  E  +    N++   NL P T Y VSI
Sbjct: 502  VTSEGFRGTWDHGASDVSLYRITWAPFGSSDK-METILNGDENTLVFENLNPNTIYEVSI 560

Query: 1520 VALNGRE-ESPLLIGQQSTVSDV--------PRDLEVVAATPTSLLISWDAPAVTVRYYR 1570
             A+   E ES  LIG + T+  +        PR+L+V  AT  SL + WD  +  V+ YR
Sbjct: 561  TAIYPDESESDDLIGSERTLPILTTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYR 620

Query: 1571 ITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVT-----GRGDSPASSKPI 1625
            ITY  + G    Q  T+ G +++  +  LKP   YTITV ++      GR      +KP+
Sbjct: 621  ITYQPSTGEGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPL 680

Query: 1626 SINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQ 1685
            +            ++V D   ++++V+W  +      Y++   P  G GP +      + 
Sbjct: 681  NT--------VRNLRVYDPSTSTLNVRWDHAEGNPRQYKLFYAPAAG-GPEELVPIPGNT 731

Query: 1686 TEMTIEGLQPTVEY---VVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIA 1742
                +  LQP   Y   VV VY +   G +    +T +  + R   +   +   +S+ + 
Sbjct: 732  NYAILRNLQPDTSYTVTVVPVYTEGDGGRTSDTGRTLMRGLAR--NVQVYNPTPNSLDVR 789

Query: 1743 WESPQGQVSRYRVTYSSPEDGIH--ELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDM 1800
            W+   G V +YRV YS P DG    E    P G      L+ L P + Y+V++VAL+ D 
Sbjct: 790  WDPAPGPVLQYRVVYS-PVDGTRPSESIVVP-GNTRMVHLERLIPDTLYSVNLVALYSDG 847

Query: 1801 ESQPLIGTQSTAIP--APTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKE 1858
            E  P    Q   +P   P +L+    T  SLS  W   +  +  YR+  +P     P+ E
Sbjct: 848  EGNPS-PAQGRTLPRSGPRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGD-PIDE 905

Query: 1859 INLAPDS-SSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDAT 1917
                P   ++V++  L   T Y+++V A+ +        G   T+  + PP+   ++D  
Sbjct: 906  YTTVPGRRNNVILQPLQPDTPYKITVIAVYEDGDGGHLTGNGRTV-GLLPPQNIHISDEW 964

Query: 1918 ETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTL 1977
             T   +SW      + G+++   P     P++  +  ++ SYT+  L P T Y + +Y  
Sbjct: 965  YTRFRVSWDPSPSPVLGYKIVYKPVGSNEPMEAFVG-EMTSYTLHNLNPSTTYDVNVYAQ 1023

Query: 1978 NDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPRE 2037
             D+  S P+    +T     ++L+      ++  V W P RA  T Y +K   P    R 
Sbjct: 1024 YDSGLSVPLTDQGTTLYLNVTDLKTYQIGWDTFCVKWSPHRA-ATSYRLKL-SPADGTRG 1081

Query: 2038 VVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPL-IGRKKTVQKTPFVTHP 2092
                 R   T    TGL P T+Y + V     N +   + +    TV+ T   T P
Sbjct: 1082 QEITVRGSETSHCFTGLSPDTDYGVTVFVQTPNLEGPGVSVKEHTTVKPTEAPTEP 1137



 Score =  261 bits (667), Expect = 6e-69
 Identities = 250/933 (26%), Positives = 398/933 (42%), Gaps = 51/933 (5%)

Query: 728  VTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYI 787
            ++E T  SF VSW   SD+V  ++VEY     G + Q   +    TS  + DL P  +Y+
Sbjct: 229  ISERTHRSFRVSWTPPSDSVDRYKVEY-YPVSGGKRQEFYVSRMETSTVLKDLKPETEYV 287

Query: 788  VNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSP 847
            VNVY + ED E S  L  ++ T P       +  V  T++ V+W +P    TGY + Y P
Sbjct: 288  VNVYSVVED-EYSEPLKGTEKTLPVPVVSLNIYDVGPTTMHVQW-QPVGGATGYILSYKP 345

Query: 848  SVEGSST---ELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRS 904
              +   T   E+ L  T N + L+DL P  +Y +T+ AV  +  S PV +++ T   PR 
Sbjct: 346  VKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEPVTVREVTLPLPR- 404

Query: 905  DTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRN-TFAE 963
                 P+DL+  +VT   + + W P    V  Y   ++    P E  + + + R+ T   
Sbjct: 405  -----PQDLKLRDVTHSTMNVFWEPVPGKVRKY---IVRYKTPEEDVKEVEVDRSETSTS 456

Query: 964  VTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTK-LDAPTNLQFVNETDSTVLVRWTPPRA 1022
            +  L     Y   V AV    ES P+TAQ+TT+ + APTNL+    T       W    +
Sbjct: 457  LKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPAPTNLKITEVTSEGFRGTWDHGAS 516

Query: 1023 QITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQE-------S 1075
             ++ YR+T          +  +    +     NL P + Y VS+ AI  ++        S
Sbjct: 517  DVSLYRITWAPFGSSDKMETILNGDENTLVFENLNPNTIYEVSITAIYPDESESDDLIGS 576

Query: 1076 PKATGVFTTLQPGSSIPPYNTEV---TETTIVITWTPAP-RI-GFKLGVRPS--QGGEAP 1128
             +   + TT  P S   P N +V   T  ++ + W PA  R+  +++  +PS  +G E  
Sbjct: 577  ERTLPILTTQAPKSG--PRNLQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQT 634

Query: 1129 REVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDT 1188
              +     S+V+  L P   Y  T+  L    E           PL+   NL +  +P T
Sbjct: 635  TTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRV-YDPST 693

Query: 1189 GVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVY 1248
              L V W+ +   +   Y++   P  G  G      +  + +     NL P   Y V+V 
Sbjct: 694  STLNVRWDHA-EGNPRQYKLFYAPAAG--GPEELVPIPGNTNYAILRNLQPDTSYTVTVV 750

Query: 1249 TVKDDKESVPISDTIIPEVPQLT-DLSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGE 1307
             V  + +    SDT    +  L  ++   + T +S+ +RW P     ++ YR+       
Sbjct: 751  PVYTEGDGGRTSDTGRTLMRGLARNVQVYNPTPNSLDVRWDPA-PGPVLQYRVVYSPVDG 809

Query: 1308 GIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAV-PPPTDLRF 1366
              P     V  +     +  L P   Y ++++ L + GE  P+    +T     P +LR 
Sbjct: 810  TRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGRTLPRSGPRNLRV 869

Query: 1367 TNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYV 1426
                 +++ V W       +  + + YSP   +      ++    N V+L  L P T Y 
Sbjct: 870  FGETTNSLSVAWDHADG-PVQQYRIIYSPTVGDPIDEYTTVPGRRNNVILQPLQPDTPYK 928

Query: 1427 VSVSSVYEQHESTPLRGRQKT-GLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHP 1485
            ++V +VYE  +   L G  +T GL  P  I  SD     F V W    + + GY+I + P
Sbjct: 929  ITVIAVYEDGDGGHLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPSPVLGYKIVYKP 988

Query: 1486 EHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDL 1545
               S  P E  V     S TL NL P T Y V++ A      S  L  Q +T+     DL
Sbjct: 989  VG-SNEPMEAFV-GEMTSYTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQGTTLYLNVTDL 1046

Query: 1546 EVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDY 1605
            +       +  + W +P      YR+      G    QE TV GS+++   +GL P  DY
Sbjct: 1047 KTYQIGWDTFCVKW-SPHRAATSYRLKLSPADGTRG-QEITVRGSETSHCFTGLSPDTDY 1104

Query: 1606 TITVYAVTGRGDSPASSKPISINYRTEIDKPSQ 1638
             +TV+  T   + P     +S+   T + KP++
Sbjct: 1105 GVTVFVQTPNLEGPG----VSVKEHTTV-KPTE 1132



 Score =  259 bits (661), Expect = 3e-68
 Identities = 236/916 (25%), Positives = 391/916 (42%), Gaps = 55/916 (6%)

Query: 997  LDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNL 1056
            L+AP+NL     T  +  V WTPP   +  Y++       G+ +++ V    +   L++L
Sbjct: 221  LEAPSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSGGKRQEFYVSRMETSTVLKDL 280

Query: 1057 QPASEYTVSLVAIKGNQESPKATGVFTTLQ-PGSSIPPYNTEVTETTIVITWTP-APRIG 1114
            +P +EY V++ ++  ++ S    G   TL  P  S+  Y  +V  TT+ + W P     G
Sbjct: 281  KPETEYVVNVYSVVEDEYSEPLKGTEKTLPVPVVSLNIY--DVGPTTMHVQWQPVGGATG 338

Query: 1115 FKLGVRPSQGGEAPREVTSDSGSIV----VSGLTPGVEYVYTIQVLRDGQERDAPIVNKV 1170
            + L  +P +  E  R      G  V    ++ L P  EY  T+Q +      +   V +V
Sbjct: 339  YILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYAVTVQAVLHDLTSEPVTVREV 398

Query: 1171 VTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQS 1230
              PL  P +L L  +     + V WE    P      I    T  +    +E  V   ++
Sbjct: 399  TLPLPRPQDLKLR-DVTHSTMNVFWE--PVPGKVRKYIVRYKTPEEDVKEVE--VDRSET 453

Query: 1231 SCTFDNLSPGLEYNVSVYTVKDDKESVPIS--DTIIPEVPQLTDLSFVDITDSSIGLRWT 1288
            S +  +L     Y VSV  V D+ ES P++  +T  P VP  T+L   ++T       W 
Sbjct: 454  STSLKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRP-VPAPTNLKITEVTSEGFRGTWD 512

Query: 1289 PLNSSTIIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITL------- 1341
               +S +  YRIT    G    + E  ++          L P   Y++S+  +       
Sbjct: 513  H-GASDVSLYRITWAPFGSSDKM-ETILNGDENTLVFENLNPNTIYEVSITAIYPDESES 570

Query: 1342 --INGGESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNE 1399
              + G E     LT Q     P +L+  N   +++ V W  P S  +  + + Y P   E
Sbjct: 571  DDLIGSERTLPILTTQAPKSGPRNLQVYNATSNSLTVKW-DPASGRVQKYRITYQPSTGE 629

Query: 1400 EDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKT-GLDSPTGIDFS 1458
             +    +I    N+VVL  L P T Y ++VSS+Y   E   + GR KT  L++   +   
Sbjct: 630  GNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRVY 689

Query: 1459 DITANSFTVHWIAPRATITGYRIRHHPEHFSGRPRE-DRVPHSRNSITLTNLTPGTEYVV 1517
            D + ++  V W         Y++ + P   +G P E   +P + N   L NL P T Y V
Sbjct: 690  DPSTSTLNVRWDHAEGNPRQYKLFYAPA--AGGPEELVPIPGNTNYAILRNLQPDTSYTV 747

Query: 1518 SIVAL-----NGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRIT 1572
            ++V +      GR         ++ +  + R+++V   TP SL + WD     V  YR+ 
Sbjct: 748  TVVPVYTEGDGGRTSDT----GRTLMRGLARNVQVYNPTPNSLDVRWDPAPGPVLQYRVV 803

Query: 1573 YGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGD---SPASSKPISINY 1629
            Y    G  P +   VPG+     +  L P   Y++ + A+   G+   SPA  + +  + 
Sbjct: 804  YSPVDGTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGRTLPRS- 862

Query: 1630 RTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMT 1689
                  P  ++V     NS+SV W  +  PV  YR+  +P  G    +  T    +  + 
Sbjct: 863  -----GPRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVPGRRNNVI 917

Query: 1690 IEGLQPTVEYVVSVYAQNPSGESQPLVQTAVT-NIDRPKGLAFTDVDVDSIKIAWESPQG 1748
            ++ LQP   Y ++V A    G+   L     T  +  P+ +  +D      +++W+    
Sbjct: 918  LQPLQPDTPYKITVIAVYEDGDGGHLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPS 977

Query: 1749 QVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGT 1808
             V  Y++ Y     G +E   A  GE  +  L  L P + Y V+V A +D   S PL   
Sbjct: 978  PVLGYKIVYKPV--GSNEPMEAFVGEMTSYTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQ 1035

Query: 1809 QSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSV 1868
             +T     TDLK  Q+   +   +W+P     T YR++++P + T   +EI +    +S 
Sbjct: 1036 GTTLYLNVTDLKTYQIGWDTFCVKWSPHRA-ATSYRLKLSPADGTRG-QEITVRGSETSH 1093

Query: 1869 VVSGLMVATKYEVSVY 1884
              +GL   T Y V+V+
Sbjct: 1094 CFTGLSPDTDYGVTVF 1109



 Score =  244 bits (622), Expect = 1e-63
 Identities = 235/925 (25%), Positives = 386/925 (41%), Gaps = 55/925 (5%)

Query: 812  DAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQ 871
            +AP +  + +    S  V W+ P   +  Y++ Y P   G   E  +     S  L DL+
Sbjct: 222  EAPSNLVISERTHRSFRVSWTPPSDSVDRYKVEYYPVSGGKRQEFYVSRMETSTVLKDLK 281

Query: 872  PGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE 931
            P  +Y + +Y+V E++ S P+       GT ++  VP    L   +V    + + W P  
Sbjct: 282  PETEYVVNVYSVVEDEYSEPL------KGTEKTLPVPVV-SLNIYDVGPTTMHVQWQPVG 334

Query: 932  SAVTGYRVDVIPV-----NLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRES 986
             A TGY +   PV       P E   RL  + N   ++T L P   Y   V AV H   S
Sbjct: 335  GA-TGYILSYKPVKDTEPTRPKE--VRLGPTVNDM-QLTDLVPNTEYAVTVQAVLHDLTS 390

Query: 987  KPLTAQQTT-KLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVG 1045
            +P+T ++ T  L  P +L+  + T ST+ V W P   ++  Y +    T     ++  V 
Sbjct: 391  EPVTVREVTLPLPRPQDLKLRDVTHSTMNVFWEPVPGKVRKY-IVRYKTPEEDVKEVEVD 449

Query: 1046 PSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVI 1105
             S +   L++L   + YTVS+ A+    ESP  T   TT    +      TEVT      
Sbjct: 450  RSETSTSLKDLFSQTLYTVSVSAVHDEGESPPVTAQETTRPVPAPTNLKITEVTSEGFRG 509

Query: 1106 TWTPAPRIGFKLGVRPSQGGEAPREVT---SDSGSIVVSGLTPGVEYVYTIQVLRD---- 1158
            TW           +  +  G + +  T    D  ++V   L P   Y  +I  +      
Sbjct: 510  TWDHGASDVSLYRITWAPFGSSDKMETILNGDENTLVFENLNPNTIYEVSITAIYPDESE 569

Query: 1159 -----GQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPT 1213
                 G ER  PI+     P S P NL +  N  +  LTV W+   +  +  YRIT  P+
Sbjct: 570  SDDLIGSERTLPILT-TQAPKSGPRNLQV-YNATSNSLTVKWD-PASGRVQKYRITYQPS 626

Query: 1214 NGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDT-IIPEVPQLTD 1272
             G +GN     +   Q+S     L P   Y ++V ++  D E   ++       +  + +
Sbjct: 627  TG-EGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVRN 685

Query: 1273 LSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAG---EGIPIFEDFVDSSVGYYTVTGLE 1329
            L   D + S++ +RW     +          AAG   E +PI       +  Y  +  L+
Sbjct: 686  LRVYDPSTSTLNVRWDHAEGNPRQYKLFYAPAAGGPEELVPI-----PGNTNYAILRNLQ 740

Query: 1330 PGIDYDISVITLINGGESAPTTLTQQTAVPP-PTDLRFTNIGPDTMRVTWAPPPSIDLTN 1388
            P   Y ++V+ +   G+   T+ T +T +     +++  N  P+++ V W P P   +  
Sbjct: 741  PDTSYTVTVVPVYTEGDGGRTSDTGRTLMRGLARNVQVYNPTPNSLDVRWDPAPG-PVLQ 799

Query: 1389 FLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKT- 1447
            + V YSPV        + +  +   V L  L+P T Y V++ ++Y   E  P   + +T 
Sbjct: 800  YRVVYSPVDGTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGRTL 859

Query: 1448 GLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLT 1507
                P  +     T NS +V W      +  YRI + P           VP  RN++ L 
Sbjct: 860  PRSGPRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVPGRRNNVILQ 919

Query: 1508 NLTPGTEYVVSIVALNGREESPLLIGQQSTVSDV-PRDLEVVAATPTSLLISWDAPAVTV 1566
             L P T Y ++++A+    +   L G   TV  + P+++ +     T   +SWD     V
Sbjct: 920  PLQPDTPYKITVIAVYEDGDGGHLTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPSPV 979

Query: 1567 RYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPIS 1626
              Y+I Y   G N P++ F   G  ++ T+  L P   Y + VYA    G     S P++
Sbjct: 980  LGYKIVYKPVGSNEPMEAFV--GEMTSYTLHNLNPSTTYDVNVYAQYDSG----LSVPLT 1033

Query: 1627 INYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQT 1686
                T     + ++   +  ++  VKW P  +  T YR+  +P +G    +    G  +T
Sbjct: 1034 DQGTTLYLNVTDLKTYQIGWDTFCVKWSPHRA-ATSYRLKLSPADGTRGQEITVRG-SET 1091

Query: 1687 EMTIEGLQPTVEYVVSVYAQNPSGE 1711
                 GL P  +Y V+V+ Q P+ E
Sbjct: 1092 SHCFTGLSPDTDYGVTVFVQTPNLE 1116



 Score =  201 bits (510), Expect = 9e-51
 Identities = 214/835 (25%), Positives = 345/835 (41%), Gaps = 77/835 (9%)

Query: 623  PNSHPIQWNAPQP-SHISKYILRWRPKNSVG--RWKEATIPGHLNSYTIKGLKPGVVYEG 679
            P +  +QW   QP    + YIL ++P       R KE  +   +N   +  L P   Y  
Sbjct: 323  PTTMHVQW---QPVGGATGYILSYKPVKDTEPTRPKEVRLGPTVNDMQLTDLVPNTEYA- 378

Query: 680  QLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSE-SVTEITASSFVV 738
              +++Q   H            TS PVT   VT       PL    +  + ++T S+  V
Sbjct: 379  --VTVQAVLHD----------LTSEPVTVREVT------LPLPRPQDLKLRDVTHSTMNV 420

Query: 739  SWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGE 798
             W      V  + V Y+  EE  +   +D   T+TS+   DL     Y V+V  + ++GE
Sbjct: 421  FWEPVPGKVRKYIVRYKTPEEDVKEVEVDRSETSTSLK--DLFSQTLYTVSVSAVHDEGE 478

Query: 799  QSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNL 858
               + +   T    AP +  + +V        W    + ++ YRI ++P       E  L
Sbjct: 479  SPPVTAQETTRPVPAPTNLKITEVTSEGFRGTWDHGASDVSLYRITWAPFGSSDKMETIL 538

Query: 859  PETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQE------TTGTPRSDTVPSPRD 912
                N++   +L P   Y ++I A+  ++  +  +I  E      TT  P+S     PR+
Sbjct: 539  NGDENTLVFENLNPNTIYEVSITAIYPDESESDDLIGSERTLPILTTQAPKS----GPRN 594

Query: 913  LQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVT 972
            LQ    T   +T+ W P    V  YR+   P    G         R     +  L P   
Sbjct: 595  LQVYNATSNSLTVKWDPASGRVQKYRITYQPSTGEGNEQTTTIGGRQNSVVLQKLKPDTP 654

Query: 973  YYFKVFAVSHGRESKPLTAQQTTK-LDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTV 1031
            Y   V ++    E   +T +  TK L+   NL+  + + ST+ VRW         Y+L  
Sbjct: 655  YTITVSSLYPDGEGGRMTGRGKTKPLNTVRNLRVYDPSTSTLNVRWDHAEGNPRQYKLFY 714

Query: 1032 GLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPG--S 1089
                 G      +  + +   LRNLQP + YTV++V +    +  + +    TL  G   
Sbjct: 715  APAAGGPEELVPIPGNTNYAILRNLQPDTSYTVTVVPVYTEGDGGRTSDTGRTLMRGLAR 774

Query: 1090 SIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSG------- 1142
            ++  YN   T  ++ + W PAP    +  V  S     P + T  S SIVV G       
Sbjct: 775  NVQVYNP--TPNSLDVRWDPAPGPVLQYRVVYS-----PVDGTRPSESIVVPGNTRMVHL 827

Query: 1143 --LTPGVEY-VYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERST 1199
              L P   Y V  + +  DG+   +P   + + P S P NL +     T  L+V+W+ + 
Sbjct: 828  ERLIPDTLYSVNLVALYSDGEGNPSPAQGRTL-PRSGPRNLRV-FGETTNSLSVAWDHAD 885

Query: 1200 TPDITGYRITTTPTNGQQGNSLEE--VVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESV 1257
             P +  YRI  +PT    G+ ++E   V   +++     L P   Y ++V  V +D +  
Sbjct: 886  GP-VQQYRIIYSPT---VGDPIDEYTTVPGRRNNVILQPLQPDTPYKITVIAVYEDGDGG 941

Query: 1258 PISD---TIIPEVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIFED 1314
             ++    T+    PQ   +S  D   +   + W P + S ++GY+I     G   P+ E 
Sbjct: 942  HLTGNGRTVGLLPPQNIHIS--DEWYTRFRVSWDP-SPSPVLGYKIVYKPVGSNEPM-EA 997

Query: 1315 FVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAVPPPTDLRFTNIGPDTM 1374
            FV      YT+  L P   YD++V    + G S P T    T     TDL+   IG DT 
Sbjct: 998  FVGEMTS-YTLHNLNPSTTYDVNVYAQYDSGLSVPLTDQGTTLYLNVTDLKTYQIGWDTF 1056

Query: 1375 RVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSV 1429
             V W+P  +   T++ ++ SP        E+++  S+ +   T L P T+Y V+V
Sbjct: 1057 CVKWSPHRA--ATSYRLKLSPADGTRG-QEITVRGSETSHCFTGLSPDTDYGVTV 1108



 Score =  152 bits (385), Expect = 3e-36
 Identities = 148/634 (23%), Positives = 250/634 (39%), Gaps = 37/634 (5%)

Query: 636  SHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRF 695
            S +S Y + W P  S  +  E  + G  N+   + L P  +YE   +SI      E    
Sbjct: 516  SDVSLYRITWAPFGSSDKM-ETILNGDENTLVFENLNPNTIYE---VSITAIYPDESESD 571

Query: 696  DFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYE 755
            D   +  + P+        TT        +  V   T++S  V W  AS  V  +R+ Y+
Sbjct: 572  DLIGSERTLPIL-------TTQAPKSGPRNLQVYNATSNSLTVKWDPASGRVQKYRITYQ 624

Query: 756  LSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPP 815
             S      Q   +     SV +  L P   Y + V  +  DGE   +    +T   +   
Sbjct: 625  PSTGEGNEQTTTIGGRQNSVVLQKLKPDTPYTITVSSLYPDGEGGRMTGRGKTKPLNTVR 684

Query: 816  DPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQ 875
            +  V     +++ VRW   +     Y++ Y+P+  G    + +P   N   L +LQP   
Sbjct: 685  NLRVYDPSTSTLNVRWDHAEGNPRQYKLFYAPAAGGPEELVPIPGNTNYAILRNLQPDTS 744

Query: 876  YNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVT 935
            Y +T+  V    +         T+ T R+      R++Q    T   + + W P    V 
Sbjct: 745  YTVTVVPVYTEGDG------GRTSDTGRTLMRGLARNVQVYNPTPNSLDVRWDPAPGPVL 798

Query: 936  GYRVDVIPVNLPGEHGQRLPISRNT-FAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQ-Q 993
             YRV   PV+      + + +  NT    +  L P   Y   + A+    E  P  AQ +
Sbjct: 799  QYRVVYSPVD-GTRPSESIVVPGNTRMVHLERLIPDTLYSVNLVALYSDGEGNPSPAQGR 857

Query: 994  TTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPS-VSKYP 1052
            T     P NL+   ET +++ V W      +  YR+    T      +Y   P   +   
Sbjct: 858  TLPRSGPRNLRVFGETTNSLSVAWDHADGPVQQYRIIYSPTVGDPIDEYTTVPGRRNNVI 917

Query: 1053 LRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTE---TTIVITW-- 1107
            L+ LQP + Y ++++A+  + +    TG   T+     +PP N  +++   T   ++W  
Sbjct: 918  LQPLQPDTPYKITVIAVYEDGDGGHLTGNGRTV---GLLPPQNIHISDEWYTRFRVSWDP 974

Query: 1108 TPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIV 1167
            +P+P +G+K+  +P    E       +  S  +  L P   Y   +    D      P+ 
Sbjct: 975  SPSPVLGYKIVYKPVGSNEPMEAFVGEMTSYTLHNLNPSTTYDVNVYAQYD-SGLSVPLT 1033

Query: 1168 NKVVTPLSPPTNLH-LEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVH 1226
            ++  T     T+L   +   DT    V W  S     T YR+  +P +G +G   E  V 
Sbjct: 1034 DQGTTLYLNVTDLKTYQIGWDT--FCVKW--SPHRAATSYRLKLSPADGTRGQ--EITVR 1087

Query: 1227 ADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS 1260
              ++S  F  LSP  +Y V+V+    + E   +S
Sbjct: 1088 GSETSHCFTGLSPDTDYGVTVFVQTPNLEGPGVS 1121



 Score = 65.9 bits (159), Expect = 5e-10
 Identities = 75/320 (23%), Positives = 125/320 (39%), Gaps = 32/320 (10%)

Query: 595  GEWHCQPLQ--TYPSSSGP--VEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNS 650
            GE +  P Q  T P S GP  + VF   T    NS  + W+      + +Y + + P   
Sbjct: 847  GEGNPSPAQGRTLPRS-GPRNLRVFGETT----NSLSVAWDHAD-GPVQQYRIIYSPTVG 900

Query: 651  VGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNT 710
                +  T+PG  N+  ++ L+P   Y+  +I++ + G                      
Sbjct: 901  DPIDEYTTVPGRRNNVILQPLQPDTPYKITVIAVYEDGD------------------GGH 942

Query: 711  VTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPS 770
            +TG       L   +  +++   + F VSW  +   V G+++ Y+    G          
Sbjct: 943  LTGNGRTVGLLPPQNIHISDEWYTRFRVSWDPSPSPVLGYKIVYK--PVGSNEPMEAFVG 1000

Query: 771  TATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVR 830
              TS  + +L P   Y VNVY   + G  S+ L+   TT      D    Q+   +  V+
Sbjct: 1001 EMTSYTLHNLNPSTTYDVNVYAQYDSG-LSVPLTDQGTTLYLNVTDLKTYQIGWDTFCVK 1059

Query: 831  WSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQEST 890
            WS P    T YR+  SP+      E+ +  +  S   + L P   Y +T++    N E  
Sbjct: 1060 WS-PHRAATSYRLKLSPADGTRGQEITVRGSETSHCFTGLSPDTDYGVTVFVQTPNLEGP 1118

Query: 891  PVVIQQETTGTPRSDTVPSP 910
             V +++ TT  P       P
Sbjct: 1119 GVSVKEHTTVKPTEAPTEPP 1138


>gi|4502961 alpha 1 type VII collagen precursor [Homo sapiens]
          Length = 2944

 Score =  220 bits (561), Expect = 1e-56
 Identities = 217/858 (25%), Positives = 372/858 (43%), Gaps = 62/858 (7%)

Query: 988  PLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLT-VGLTRRGQP-----RQ 1041
            P+T        AP +L     +  ++ V+WT     +TGY++    LT  GQP     ++
Sbjct: 223  PVTRPPDDSTSAPRDLVLSEPSSQSLRVQWTAASGPVTGYKVQYTPLTGLGQPLPSERQE 282

Query: 1042 YNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVF-TTLQPGSSIPPYNTEVTE 1100
             NV    +   LR L+P +EY V+++A+  N      +G   TT   G  +   NT  T 
Sbjct: 283  VNVPAGETSVRLRGLRPLTEYQVTVIALYANSIGEAVSGTARTTALEGPELTIQNT--TA 340

Query: 1101 TTIVITWTPAP-RIGFKLGVRPSQGGEAPR-EVTSDSGSIVVSGLTPGVEYVYTIQVLRD 1158
             ++++ W   P   G+++  R   GG   + E+    GS+++  L PG +Y  T+  L  
Sbjct: 341  HSLLVAWRSVPGATGYRVTWRVLSGGPTQQQELGPGQGSVLLRDLEPGTDYEVTVSTLF- 399

Query: 1159 GQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQG 1218
            G+           T  S    L       T +L +SW  +  P+  GYR+      G + 
Sbjct: 400  GRSVGPATSLMARTDASVEQTLRPVILGPTSIL-LSW--NLVPEARGYRLEWRRETGLEP 456

Query: 1219 NSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPEVPQL-----TDL 1273
               + V+ +D +    D L PG EY +++YT+ +  E V    T++P  P+L     TDL
Sbjct: 457  PQ-KVVLPSDVTRYQLDGLQPGTEYRLTLYTLLEGHE-VATPATVVPTGPELPVSPVTDL 514

Query: 1274 SFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGID 1333
               ++    + + W+P+  +T   YRI +V + +G+        S   +  +  ++ G+ 
Sbjct: 515  QATELPGQRVRVSWSPVPGAT--QYRI-IVRSTQGVERTLVLPGSQTAF-DLDDVQAGLS 570

Query: 1334 YDISVITLINGGESAPTTLTQQTAVPPPT---DLRFTNIGPDTMRVTWAPPPSIDLTNFL 1390
            Y + V   +   E + + LT +     P     LR        +RV W P P    + F 
Sbjct: 571  YTVRVSARVGPREGSASVLTVRREPETPLAVPGLRVVVSDATRVRVAWGPVPGA--SGFR 628

Query: 1391 VRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLD 1450
            + +S     E  +  ++ P   A  +T L PGT Y V+VS +  + E        +T   
Sbjct: 629  ISWSTGSGPE--SSQTLPPDSTATDITGLQPGTTYQVAVSVLRGREEGPAAVIVARTDPL 686

Query: 1451 SPTG-IDFSDITANSFTVHWI-APRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTN 1508
             P   +  +  +++S T+ W   P AT  GYR+  H  H  G  +   V        L  
Sbjct: 687  GPVRTVHVTQASSSSVTITWTRVPGAT--GYRVSWHSAH--GPEKSQLVSGEATVAELDG 742

Query: 1509 LTPGTEYVVSIVA----LNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAV 1564
            L P TEY V + A    ++G   S ++      V  V R L+++ A+   L I+W     
Sbjct: 743  LEPDTEYTVHVRAHVAGVDGPPASVVVRTAPEPVGRVSR-LQILNASSDVLRITW-VGVT 800

Query: 1565 TVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKP 1624
                YR+ +G + G  P++   +PG+  +A I GL+ GV Y++ V A+ G  +      P
Sbjct: 801  GATAYRLAWGRSEGG-PMRHQILPGNTDSAEIRGLEGGVSYSVRVTALVGDREGT----P 855

Query: 1625 ISINYRTEIDKP---SQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTA 1681
            +SI   T  + P     + V    ++S+ ++W P      G+ +   P+ G    +++  
Sbjct: 856  VSIVVTTPPEAPPALGTLHVVQRGEHSLRLRWEPVPR-AQGFLLHWQPEGGQ--EQSRVL 912

Query: 1682 GPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKG--LAFTDVDVDSI 1739
            GP+ +   ++GL+P  +Y V +    P+GE      TA T   R     L   D  +DS+
Sbjct: 913  GPELSSYHLDGLEPATQYRVRLSVLGPAGEGPSAEVTARTESPRVPSIELRVVDTSIDSV 972

Query: 1740 KIAWESPQGQVSRYRVTYSSPEDGIHELFPAPD---GEEDTAELQGLRPGSEYTVSVVAL 1796
             +AW +P  + S Y +++        E+  +P    G   +  + GL PG  Y  S+  +
Sbjct: 973  TLAW-TPVSRASSYILSWRPLRGPGQEVPGSPQTLPGISSSQRVTGLEPGVSYIFSLTPV 1031

Query: 1797 HDDMESQPLIGTQSTAIP 1814
             D +       TQ+   P
Sbjct: 1032 LDGVRGPEASVTQTPVCP 1049



 Score =  218 bits (556), Expect = 4e-56
 Identities = 223/844 (26%), Positives = 359/844 (42%), Gaps = 56/844 (6%)

Query: 1165 PIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSL--- 1221
            P+        S P +L L + P +  L V W  ++ P +TGY++  TP  G  G  L   
Sbjct: 223  PVTRPPDDSTSAPRDLVL-SEPSSQSLRVQWTAASGP-VTGYKVQYTPLTGL-GQPLPSE 279

Query: 1222 --EEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPEVPQLTDLSFVDIT 1279
              E  V A ++S     L P  EY V+V  +  +     +S T      +  +L+  + T
Sbjct: 280  RQEVNVPAGETSVRLRGLRPLTEYQVTVIALYANSIGEAVSGTARTTALEGPELTIQNTT 339

Query: 1280 DSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVI 1339
              S+ + W  +  +T  GYR+T      G P  +  +    G   +  LEPG DY+++V 
Sbjct: 340  AHSLLVAWRSVPGAT--GYRVTWRVLSGG-PTQQQELGPGQGSVLLRDLEPGTDYEVTVS 396

Query: 1340 TLINGGESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNE 1399
            TL        T+L  +T       LR   +GP ++ ++W   P  +   + + +      
Sbjct: 397  TLFGRSVGPATSLMARTDASVEQTLRPVILGPTSILLSWNLVP--EARGYRLEWRRETGL 454

Query: 1400 EDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSP----TGI 1455
            E   ++ +        L  L PGTEY +++ ++ E HE         TG + P    T +
Sbjct: 455  EPPQKVVLPSDVTRYQLDGLQPGTEYRLTLYTLLEGHEVATPATVVPTGPELPVSPVTDL 514

Query: 1456 DFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEY 1515
              +++      V W +P    T YRI        G  R   +P S+ +  L ++  G  Y
Sbjct: 515  QATELPGQRVRVSW-SPVPGATQYRIIVRSTQ--GVERTLVLPGSQTAFDLDDVQAGLSY 571

Query: 1516 VVSIVALNGREE---SPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRIT 1572
             V + A  G  E   S L + ++         L VV +  T + ++W  P      +RI+
Sbjct: 572  TVRVSARVGPREGSASVLTVRREPETPLAVPGLRVVVSDATRVRVAW-GPVPGASGFRIS 630

Query: 1573 YGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTE 1632
            +    G+ P    T+P   +   I+GL+PG  Y + V  + GR + PA+     I  RT+
Sbjct: 631  WST--GSGPESSQTLPPDSTATDITGLQPGTTYQVAVSVLRGREEGPAAV----IVARTD 684

Query: 1633 IDKPSQ-MQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIE 1691
               P + + VT    +S+++ W       TGYRV+    +  GP K++    + T   ++
Sbjct: 685  PLGPVRTVHVTQASSSSVTITWTRVPG-ATGYRVSW--HSAHGPEKSQLVSGEATVAELD 741

Query: 1692 GLQPTVEYVVSVYAQNPSGESQP---LVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQG 1748
            GL+P  EY V V A     +  P   +V+TA   + R   L   +   D ++I W    G
Sbjct: 742  GLEPDTEYTVHVRAHVAGVDGPPASVVVRTAPEPVGRVSRLQILNASSDVLRITWVGVTG 801

Query: 1749 QVSRYRVTYSSPEDGI--HELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPL- 1805
              + YR+ +   E G   H++ P   G  D+AE++GL  G  Y+V V AL  D E  P+ 
Sbjct: 802  ATA-YRLAWGRSEGGPMRHQILP---GNTDSAEIRGLEGGVSYSVRVTALVGDREGTPVS 857

Query: 1806 --IGTQSTAIPAPTDLKFTQVTPTSLSAQWTP-PNVQLTGYRVRVTPKEKTGPMKEINLA 1862
              + T   A PA   L   Q    SL  +W P P  Q  G+ +   P+   G  +   L 
Sbjct: 858  IVVTTPPEAPPALGTLHVVQRGEHSLRLRWEPVPRAQ--GFLLHWQPEG--GQEQSRVLG 913

Query: 1863 PDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTIT 1922
            P+ SS  + GL  AT+Y V +  L        A+    T     P    RV D +  ++T
Sbjct: 914  PELSSYHLDGLEPATQYRVRLSVLGPAGEGPSAEVTARTESPRVPSIELRVVDTSIDSVT 973

Query: 1923 ISWRTKTETITGFQVDAVPANG---QTPIQRTIKPDV-RSYTITGLQPGTDYKIYLYTLN 1978
            ++W T     + + +   P  G   + P      P +  S  +TGL+PG  Y   L  + 
Sbjct: 974  LAW-TPVSRASSYILSWRPLRGPGQEVPGSPQTLPGISSSQRVTGLEPGVSYIFSLTPVL 1032

Query: 1979 DNAR 1982
            D  R
Sbjct: 1033 DGVR 1036



 Score =  210 bits (534), Expect = 2e-53
 Identities = 211/874 (24%), Positives = 361/874 (41%), Gaps = 91/874 (10%)

Query: 1349 PTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKN-----EEDVA 1403
            P T     +   P DL  +     ++RV W    S  +T + V+Y+P+         +  
Sbjct: 223  PVTRPPDDSTSAPRDLVLSEPSSQSLRVQWTAA-SGPVTGYKVQYTPLTGLGQPLPSERQ 281

Query: 1404 ELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITAN 1463
            E+++   + +V L  L P TEY V+V ++Y       + G  +T       +   + TA+
Sbjct: 282  EVNVPAGETSVRLRGLRPLTEYQVTVIALYANSIGEAVSGTARTTALEGPELTIQNTTAH 341

Query: 1464 SFTVHWIAPRATITGYRIRHHPEHFSGRP-REDRVPHSRNSITLTNLTPGTEYVVSIVAL 1522
            S  V W +     TGYR+       SG P ++  +   + S+ L +L PGT+Y V++  L
Sbjct: 342  SLLVAWRSVPGA-TGYRVTWRV--LSGGPTQQQELGPGQGSVLLRDLEPGTDYEVTVSTL 398

Query: 1523 NGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPV 1582
             GR   P       T + V + L  V   PTS+L+SW+      R YR+ +    G  P 
Sbjct: 399  FGRSVGPATSLMARTDASVEQTLRPVILGPTSILLSWNL-VPEARGYRLEWRRETGLEPP 457

Query: 1583 QEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVT 1642
            Q+  +P   +   + GL+PG +Y +T+Y +    +    +  +       +   + +Q T
Sbjct: 458  QKVVLPSDVTRYQLDGLQPGTEYRLTLYTLLEGHEVATPATVVPTGPELPVSPVTDLQAT 517

Query: 1643 DVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVS 1702
            ++    + V W P     T YR+    ++  G  +T      QT   ++ +Q  + Y V 
Sbjct: 518  ELPGQRVRVSWSPVPG-ATQYRIIV--RSTQGVERTLVLPGSQTAFDLDDVQAGLSYTVR 574

Query: 1703 VYAQNPSGESQPLVQTAVTNIDRP---KGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSS 1759
            V A+    E    V T     + P    GL     D   +++AW  P    S +R+++S+
Sbjct: 575  VSARVGPREGSASVLTVRREPETPLAVPGLRVVVSDATRVRVAW-GPVPGASGFRISWST 633

Query: 1760 PEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPT-D 1818
                       PD      ++ GL+PG+ Y V+V  L    E    +    T    P   
Sbjct: 634  GSGPESSQTLPPD--STATDITGLQPGTTYQVAVSVLRGREEGPAAVIVARTDPLGPVRT 691

Query: 1819 LKFTQVTPTSLSAQWT-PPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVAT 1877
            +  TQ + +S++  WT  P    TGY  RV+     GP K   ++ +++   + GL   T
Sbjct: 692  VHVTQASSSSVTITWTRVPGA--TGY--RVSWHSAHGPEKSQLVSGEATVAELDGLEPDT 747

Query: 1878 KYEVSVYALKDTLTSRPAQGVVTTL-ENVSPPRRARVTDATETTITISWRTKTETITGFQ 1936
            +Y V V A    +   PA  VV T  E V    R ++ +A+   + I+W   T   T ++
Sbjct: 748  EYTVHVRAHVAGVDGPPASVVVRTAPEPVGRVSRLQILNASSDVLRITWVGVTGA-TAYR 806

Query: 1937 VDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDA 1996
            +    + G     + +  +  S  I GL+ G  Y + +  L  +   +PV I  +T  +A
Sbjct: 807  LAWGRSEGGPMRHQILPGNTDSAEIRGLEGGVSYSVRVTALVGDREGTPVSIVVTTPPEA 866

Query: 1997 P---SNLRFLATTPNSLLVSWQP-PRARITGYIIKYEKPGSPPREVVPRPRPGVTEATIT 2052
            P     L  +    +SL + W+P PRA+  G+++ ++  G   +  V  P   ++   + 
Sbjct: 867  PPALGTLHVVQRGEHSLRLRWEPVPRAQ--GFLLHWQPEGGQEQSRVLGPE--LSSYHLD 922

Query: 2053 GLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQKTPFVTHPGYDTGNGIQLPGTSGQQPSV 2112
            GLEP T+Y + +  L                                    G +G+ PS 
Sbjct: 923  GLEPATQYRVRLSVL------------------------------------GPAGEGPSA 946

Query: 2113 GQQMIFEEHGFRRTTPPTTATPIRHRPRPYPPNVGQEALSQTTISWAPFQDTSEYIISCH 2172
                   E   R  +P   +  +R         V   ++   T++W P    S YI+S  
Sbjct: 947  -------EVTARTESPRVPSIELR---------VVDTSIDSVTLAWTPVSRASSYILSWR 990

Query: 2173 PV---GTDEEPLQFRVPGTSTSATLTGLTRGATY 2203
            P+   G +       +PG S+S  +TGL  G +Y
Sbjct: 991  PLRGPGQEVPGSPQTLPGISSSQRVTGLEPGVSY 1024



 Score =  202 bits (514), Expect = 3e-51
 Identities = 226/893 (25%), Positives = 371/893 (41%), Gaps = 69/893 (7%)

Query: 696  DFTTTSTSTPVTSN----TVTGETTPFSPLVATSES----VTEITASSFVVSWVSASDTV 747
            DF+   T  P+ S     T  G      P  +TS      ++E ++ S  V W +AS  V
Sbjct: 200  DFSILRTLLPLVSRRVCTTAGGVPVTRPPDDSTSAPRDLVLSEPSSQSLRVQWTAASGPV 259

Query: 748  SGFRVEYE-LSEEGD----EPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLI 802
            +G++V+Y  L+  G     E Q +++P+  TSV +  L P  +Y V V  +  +     +
Sbjct: 260  TGYKVQYTPLTGLGQPLPSERQEVNVPAGETSVRLRGLRPLTEYQVTVIALYANSIGEAV 319

Query: 803  LSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETA 862
              T++TTA + P + T+      S++V W R     TGYR+ +     G + +  L    
Sbjct: 320  SGTARTTALEGP-ELTIQNTTAHSLLVAW-RSVPGATGYRVTWRVLSGGPTQQQELGPGQ 377

Query: 863  NSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVK 922
             SV L DL+PG  Y +T+  +          +   T  +      P       V +    
Sbjct: 378  GSVLLRDLEPGTDYEVTVSTLFGRSVGPATSLMARTDASVEQTLRP-------VILGPTS 430

Query: 923  VTIMWTPPESAVTGYRVDVI-PVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVS 981
            + + W     A  GYR++      L       LP S  T  ++ GL PG  Y   ++ + 
Sbjct: 431  ILLSWNLVPEA-RGYRLEWRRETGLEPPQKVVLP-SDVTRYQLDGLQPGTEYRLTLYTLL 488

Query: 982  HGRE-SKPLTAQQT---TKLDAPTNLQFVNETDSTVLVRWTP-PRAQITGYRLTVGLTRR 1036
             G E + P T   T     +   T+LQ        V V W+P P A  T YR+ V  T+ 
Sbjct: 489  EGHEVATPATVVPTGPELPVSPVTDLQATELPGQRVRVSWSPVPGA--TQYRIIVRSTQ- 545

Query: 1037 GQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGS--SIPPY 1094
            G  R   +  S + + L ++Q    YTV + A  G +E   A+ +    +P +  ++P  
Sbjct: 546  GVERTLVLPGSQTAFDLDDVQAGLSYTVRVSARVGPREG-SASVLTVRREPETPLAVPGL 604

Query: 1095 NTEVTETTIV-ITWTPAPRI-GFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYT 1152
               V++ T V + W P P   GF++      G E+ + +  DS +  ++GL PG  Y   
Sbjct: 605  RVVVSDATRVRVAWGPVPGASGFRISWSTGSGPESSQTLPPDSTATDITGLQPGTTYQVA 664

Query: 1153 IQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTP 1212
            + VLR  +E  A ++     PL P   +H+     + V T++W R   P  TGYR++   
Sbjct: 665  VSVLRGREEGPAAVIVARTDPLGPVRTVHVTQASSSSV-TITWTR--VPGATGYRVSWHS 721

Query: 1213 TNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTI--IPE-VPQ 1269
             +G + + L   V  + +    D L P  EY V V       +  P S  +   PE V +
Sbjct: 722  AHGPEKSQL---VSGEATVAELDGLEPDTEYTVHVRAHVAGVDGPPASVVVRTAPEPVGR 778

Query: 1270 LTDLSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLE 1329
            ++ L  ++ +   + + W  +  +T   YR+      EG P+    +  +     + GLE
Sbjct: 779  VSRLQILNASSDVLRITWVGVTGAT--AYRL-AWGRSEGGPMRHQILPGNTDSAEIRGLE 835

Query: 1330 PGIDYDISVITLINGGESAPTTL---TQQTAVPPPTDLRFTNIGPDTMRVTWAPPPSIDL 1386
             G+ Y + V  L+   E  P ++   T   A P    L     G  ++R+ W P P    
Sbjct: 836  GGVSYSVRVTALVGDREGTPVSIVVTTPPEAPPALGTLHVVQRGEHSLRLRWEPVPRAQ- 894

Query: 1387 TNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQK 1446
              FL+ + P   +E    L   P  ++  L  L P T+Y V +S +    E        +
Sbjct: 895  -GFLLHWQPEGGQEQSRVL--GPELSSYHLDGLEPATQYRVRLSVLGPAGEGPSAEVTAR 951

Query: 1447 TGLDSPTGIDFS--DITANSFTVHWIAPRATITGYRIRHHP-----EHFSGRPREDRVPH 1499
            T       I+    D + +S T+ W  P +  + Y +   P     +   G P+   +P 
Sbjct: 952  TESPRVPSIELRVVDTSIDSVTLAW-TPVSRASSYILSWRPLRGPGQEVPGSPQ--TLPG 1008

Query: 1500 SRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATP 1552
              +S  +T L PG  Y+ S+  +      P     Q+ V   PR L  V   P
Sbjct: 1009 ISSSQRVTGLEPGVSYIFSLTPVLDGVRGPEASVTQTPV--CPRGLADVVFLP 1059



 Score =  201 bits (512), Expect = 6e-51
 Identities = 216/837 (25%), Positives = 350/837 (41%), Gaps = 48/837 (5%)

Query: 1272 DLSFVDITDSSIGLRWTPLNSSTIIGYRIT---VVAAGEGIPIFEDFVDSSVGYYTVT-- 1326
            DL   + +  S+ ++WT   S  + GY++    +   G+ +P     V+   G  +V   
Sbjct: 237  DLVLSEPSSQSLRVQWTAA-SGPVTGYKVQYTPLTGLGQPLPSERQEVNVPAGETSVRLR 295

Query: 1327 GLEPGIDYDISVITLINGGESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAPPPSIDL 1386
            GL P  +Y ++VI L         + T +T      +L   N    ++ V W   P    
Sbjct: 296  GLRPLTEYQVTVIALYANSIGEAVSGTARTTALEGPELTIQNTTAHSLLVAWRSVPGA-- 353

Query: 1387 TNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQK 1446
            T + V +  V +     +  + P   +V+L +L PGT+Y V+VS+++ +          +
Sbjct: 354  TGYRVTWR-VLSGGPTQQQELGPGQGSVLLRDLEPGTDYEVTVSTLFGRSVGPATSLMAR 412

Query: 1447 TGLDSPTGIDFSDITANSFTVHW-IAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSIT 1505
            T       +    +   S  + W + P A   GYR+    E     P++  +P       
Sbjct: 413  TDASVEQTLRPVILGPTSILLSWNLVPEAR--GYRLEWRRETGLEPPQKVVLPSDVTRYQ 470

Query: 1506 LTNLTPGTEYVVSIVAL-NGRE-ESPLLI---GQQSTVSDVPRDLEVVAATPTSLLISWD 1560
            L  L PGTEY +++  L  G E  +P  +   G +  VS V  DL+        + +SW 
Sbjct: 471  LDGLQPGTEYRLTLYTLLEGHEVATPATVVPTGPELPVSPVT-DLQATELPGQRVRVSW- 528

Query: 1561 APAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPA 1620
            +P      YRI    T G    +   +PGS++   +  ++ G+ YT+ V A  G  +  A
Sbjct: 529  SPVPGATQYRIIVRSTQGVE--RTLVLPGSQTAFDLDDVQAGLSYTVRVSARVGPREGSA 586

Query: 1621 SSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKT 1680
            S   +     T +  P  ++V       + V W P     +G+R++ +   G GP  ++T
Sbjct: 587  SVLTVRREPETPLAVPG-LRVVVSDATRVRVAWGPVPG-ASGFRISWS--TGSGPESSQT 642

Query: 1681 AGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRP-KGLAFTDVDVDSI 1739
              PD T   I GLQP   Y V+V       E    V  A T+   P + +  T     S+
Sbjct: 643  LPPDSTATDITGLQPGTTYQVAVSVLRGREEGPAAVIVARTDPLGPVRTVHVTQASSSSV 702

Query: 1740 KIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSV---VAL 1796
             I W    G    YRV++ S      E      GE   AEL GL P +EYTV V   VA 
Sbjct: 703  TITWTRVPGATG-YRVSWHSAHGP--EKSQLVSGEATVAELDGLEPDTEYTVHVRAHVAG 759

Query: 1797 HDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPM 1856
             D   +  ++ T    +   + L+    +   L   W       T YR+    + + GPM
Sbjct: 760  VDGPPASVVVRTAPEPVGRVSRLQILNASSDVLRITWVGVT-GATAYRL-AWGRSEGGPM 817

Query: 1857 KEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRA-RVTD 1915
            +   L  ++ S  + GL     Y V V AL       P   VVTT     P      V  
Sbjct: 818  RHQILPGNTDSAEIRGLEGGVSYSVRVTALVGDREGTPVSIVVTTPPEAPPALGTLHVVQ 877

Query: 1916 ATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLY 1975
              E ++ + W        GF +   P  GQ    R + P++ SY + GL+P T Y++ L 
Sbjct: 878  RGEHSLRLRWEPVPRA-QGFLLHWQPEGGQEQ-SRVLGPELSSYHLDGLEPATQYRVRLS 935

Query: 1976 TLNDNARSSPVVIDAST-AIDAPS-NLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGS 2033
             L          + A T +   PS  LR + T+ +S+ ++W P  +R + YI+ +     
Sbjct: 936  VLGPAGEGPSAEVTARTESPRVPSIELRVVDTSIDSVTLAWTPV-SRASSYILSWRPLRG 994

Query: 2034 PPREV--VPRPRPGVTEA-TITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQKTP 2087
            P +EV   P+  PG++ +  +TGLEPG  Y   +  + +  +     G + +V +TP
Sbjct: 995  PGQEVPGSPQTLPGISSSQRVTGLEPGVSYIFSLTPVLDGVR-----GPEASVTQTP 1046



 Score =  182 bits (463), Expect = 3e-45
 Identities = 211/856 (24%), Positives = 366/856 (42%), Gaps = 81/856 (9%)

Query: 607  SSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGR-----WKEATIPG 661
            S+S P ++ ++E  SQ  S  +QW A     ++ Y +++ P   +G+      +E  +P 
Sbjct: 231  STSAPRDLVLSEPSSQ--SLRVQWTAAS-GPVTGYKVQYTPLTGLGQPLPSERQEVNVPA 287

Query: 662  HLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPL 721
               S  ++GL+P   Y+  +I++      E       TT+   P                
Sbjct: 288  GETSVRLRGLRPLTEYQVTVIALYANSIGEAVSGTARTTALEGP---------------- 331

Query: 722  VATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLL 781
                 ++   TA S +V+W S     +G+RV + +   G   Q  +L     SV + DL 
Sbjct: 332  ---ELTIQNTTAHSLLVAWRSVPG-ATGYRVTWRVL-SGGPTQQQELGPGQGSVLLRDLE 386

Query: 782  PGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQV--DDTSIVVRWSR-PQAPI 838
            PG  Y V V  +     +S+  +TS     DA  + T+  V    TSI++ W+  P+A  
Sbjct: 387  PGTDYEVTVSTLF---GRSVGPATSLMARTDASVEQTLRPVILGPTSILLSWNLVPEA-- 441

Query: 839  TGYRIVYSPSVE-GSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQE-STPVVIQQ 896
             GYR+ +          ++ LP       L  LQPG +Y +T+Y + E  E +TP  +  
Sbjct: 442  RGYRLEWRRETGLEPPQKVVLPSDVTRYQLDGLQPGTEYRLTLYTLLEGHEVATPATVVP 501

Query: 897  ETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPI 956
                 P S       DLQ  E+   +V + W+P   A T YR+ ++      E    LP 
Sbjct: 502  TGPELPVSPVT----DLQATELPGQRVRVSWSPVPGA-TQYRI-IVRSTQGVERTLVLPG 555

Query: 957  SRNTFAEVTGLSPGVTYYFKVFAVSHGRESK----PLTAQQTTKLDAPTNLQFVNETDST 1012
            S+  F ++  +  G++Y  +V A    RE       +  +  T L  P  L+ V    + 
Sbjct: 556  SQTAF-DLDDVQAGLSYTVRVSARVGPREGSASVLTVRREPETPLAVP-GLRVVVSDATR 613

Query: 1013 VLVRWTP-PRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKG 1071
            V V W P P A  +G+R++   T  G      + P  +   +  LQP + Y V++  ++G
Sbjct: 614  VRVAWGPVPGA--SGFRISWS-TGSGPESSQTLPPDSTATDITGLQPGTTYQVAVSVLRG 670

Query: 1072 NQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAP-RIGFKLGVRPSQGGEAPRE 1130
             +E P A  V  T   G     + T+ + +++ ITWT  P   G+++    + G E  + 
Sbjct: 671  REEGPAAVIVARTDPLGPVRTVHVTQASSSSVTITWTRVPGATGYRVSWHSAHGPEKSQL 730

Query: 1131 VTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAP----IVNKVVTPLSPPTNLHLEANP 1186
            V+ ++    + GL P  E  YT+ V       D P    +V     P+   + L +  N 
Sbjct: 731  VSGEATVAELDGLEPDTE--YTVHVRAHVAGVDGPPASVVVRTAPEPVGRVSRLQI-LNA 787

Query: 1187 DTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVS 1246
             + VL ++W   T    T YR+    + G  G    +++  +  S     L  G+ Y+V 
Sbjct: 788  SSDVLRITWVGVT--GATAYRLAWGRSEG--GPMRHQILPGNTDSAEIRGLEGGVSYSVR 843

Query: 1247 VYTVKDDKESVPISDTII--PEV-PQLTDLSFVDITDSSIGLRWTPLNSSTIIGYRITVV 1303
            V  +  D+E  P+S  +   PE  P L  L  V   + S+ LRW P+  +   G+ +   
Sbjct: 844  VTALVGDREGTPVSIVVTTPPEAPPALGTLHVVQRGEHSLRLRWEPVPRAQ--GFLLH-- 899

Query: 1304 AAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAVP--PP 1361
               EG       +   +  Y + GLEP   Y + +  L   GE     +T +T  P  P 
Sbjct: 900  WQPEGGQEQSRVLGPELSSYHLDGLEPATQYRVRLSVLGPAGEGPSAEVTARTESPRVPS 959

Query: 1362 TDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVK---NEEDVAELSISPSDNAVVLTN 1418
             +LR  +   D++ + W P      +++++ + P++    E   +  ++    ++  +T 
Sbjct: 960  IELRVVDTSIDSVTLAWTPVSR--ASSYILSWRPLRGPGQEVPGSPQTLPGISSSQRVTG 1017

Query: 1419 LLPGTEYVVSVSSVYE 1434
            L PG  Y+ S++ V +
Sbjct: 1018 LEPGVSYIFSLTPVLD 1033



 Score =  160 bits (405), Expect = 1e-38
 Identities = 184/729 (25%), Positives = 293/729 (40%), Gaps = 67/729 (9%)

Query: 562  QDSETGTFYQIGDSWEKYVHGVRYQCYCYGRGIGEWHCQPLQTYPSSSGPVEVFITETPS 621
            +D E GT Y++  S              +GR +G       +T  S    VE  +     
Sbjct: 383  RDLEPGTDYEVTVST------------LFGRSVGPATSLMARTDAS----VEQTLRPVIL 426

Query: 622  QPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQL 681
             P S  + WN    +    Y L WR +  +   ++  +P  +  Y + GL+PG  Y   L
Sbjct: 427  GPTSILLSWNLVPEAR--GYRLEWRRETGLEPPQKVVLPSDVTRYQLDGLQPGTEYRLTL 484

Query: 682  ISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWV 741
             ++ + GH+            +TP T    TG   P SP+  T    TE+      VSW 
Sbjct: 485  YTLLE-GHE-----------VATPATV-VPTGPELPVSPV--TDLQATELPGQRVRVSW- 528

Query: 742  SASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQI--SEDGEQ 799
            S     + +R+    S +G E + L LP + T+ ++ D+  G  Y V V       +G  
Sbjct: 529  SPVPGATQYRIIVR-STQGVE-RTLVLPGSQTAFDLDDVQAGLSYTVRVSARVGPREGSA 586

Query: 800  SLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLP 859
            S++    +   P A P   V   D T + V W  P    +G+RI +S    G  +   LP
Sbjct: 587  SVLTVRREPETPLAVPGLRVVVSDATRVRVAWG-PVPGASGFRISWSTG-SGPESSQTLP 644

Query: 860  ETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVT 919
              + +  ++ LQPG  Y + +  +   +E    VI        R+D +   R +   + +
Sbjct: 645  PDSTATDITGLQPGTTYQVAVSVLRGREEGPAAVI------VARTDPLGPVRTVHVTQAS 698

Query: 920  DVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFA 979
               VTI WT    A TGYRV     +  G    +L     T AE+ GL P   Y   V A
Sbjct: 699  SSSVTITWTRVPGA-TGYRVSWHSAH--GPEKSQLVSGEATVAELDGLEPDTEYTVHVRA 755

Query: 980  VSHGRESKPLTAQQTT---KLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRR 1036
               G +  P +    T    +   + LQ +N +   + + W       T YRL  G +  
Sbjct: 756  HVAGVDGPPASVVVRTAPEPVGRVSRLQILNASSDVLRITWVGVTG-ATAYRLAWGRSEG 814

Query: 1037 GQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNT 1096
            G  R   +  +     +R L+    Y+V + A+ G++E    + V TT  P  + P   T
Sbjct: 815  GPMRHQILPGNTDSAEIRGLEGGVSYSVRVTALVGDREGTPVSIVVTT--PPEAPPALGT 872

Query: 1097 ----EVTETTIVITWTPAPRI-GFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVY 1151
                +  E ++ + W P PR  GF L  +P  G E  R +  +  S  + GL P  +Y  
Sbjct: 873  LHVVQRGEHSLRLRWEPVPRAQGFLLHWQPEGGQEQSRVLGPELSSYHLDGLEPATQYRV 932

Query: 1152 TIQVLRD-GQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITT 1210
             + VL   G+   A +  +  +P  P   L +    DT + +V+   +     + Y ++ 
Sbjct: 933  RLSVLGPAGEGPSAEVTARTESPRVPSIELRV---VDTSIDSVTLAWTPVSRASSYILSW 989

Query: 1211 TPTN--GQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPEVP 1268
             P    GQ+     + +    SS     L PG+ Y  S+  V D       S T  P  P
Sbjct: 990  RPLRGPGQEVPGSPQTLPGISSSQRVTGLEPGVSYIFSLTPVLDGVRGPEASVTQTPVCP 1049

Query: 1269 Q-LTDLSFV 1276
            + L D+ F+
Sbjct: 1050 RGLADVVFL 1058



 Score =  119 bits (298), Expect = 4e-26
 Identities = 151/659 (22%), Positives = 263/659 (39%), Gaps = 82/659 (12%)

Query: 1612 VTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKN 1671
            V+ R  + A   P++         P  + +++    S+ V+W  +S PVTGY+V  TP  
Sbjct: 211  VSRRVCTTAGGVPVTRPPDDSTSAPRDLVLSEPSSQSLRVQWTAASGPVTGYKVQYTPLT 270

Query: 1672 G-----PGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRP 1726
            G     P   +       +T + + GL+P  EY V+V A   +   + +  TA T     
Sbjct: 271  GLGQPLPSERQEVNVPAGETSVRLRGLRPLTEYQVTVIALYANSIGEAVSGTARTTALEG 330

Query: 1727 KGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDG---IHELFPAPDGEEDTAELQGL 1783
              L   +    S+ +AW S  G  + YRVT+     G     EL P     + +  L+ L
Sbjct: 331  PELTIQNTTAHSLLVAWRSVPG-ATGYRVTWRVLSGGPTQQQELGPG----QGSVLLRDL 385

Query: 1784 RPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQ------VTPTSLSAQWTPPN 1837
             PG++Y V+V  L             +T++ A TD    Q      + PTS+   W    
Sbjct: 386  EPGTDYEVTVSTLFGRSVG------PATSLMARTDASVEQTLRPVILGPTSILLSWNLV- 438

Query: 1838 VQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYA-LKDTLTSRPAQ 1896
             +  GYR+    +    P +++ L  D +   + GL   T+Y +++Y  L+    + PA 
Sbjct: 439  PEARGYRLEWRRETGLEPPQKVVLPSDVTRYQLDGLQPGTEYRLTLYTLLEGHEVATPAT 498

Query: 1897 GVVTTLE-NVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRT--IK 1953
             V T  E  VSP    + T+     + +SW      + G     +       ++RT  + 
Sbjct: 499  VVPTGPELPVSPVTDLQATELPGQRVRVSW----SPVPGATQYRIIVRSTQGVERTLVLP 554

Query: 1954 PDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAP---SNLRFLATTPNSL 2010
                ++ +  +Q G  Y + +         S  V+      + P     LR + +    +
Sbjct: 555  GSQTAFDLDDVQAGLSYTVRVSARVGPREGSASVLTVRREPETPLAVPGLRVVVSDATRV 614

Query: 2011 LVSWQP-PRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKN 2069
             V+W P P A  +G+ I +   GS P      P P  T   ITGL+PGT Y + V  L+ 
Sbjct: 615  RVAWGPVPGA--SGFRISW-STGSGPESSQTLP-PDSTATDITGLQPGTTYQVAVSVLRG 670

Query: 2070 NQKSEPLIGRKKTVQKTPFVT-HPGYDTGNGI-----QLPGTSGQQPS------------ 2111
             ++    +   +T    P  T H    + + +     ++PG +G + S            
Sbjct: 671  REEGPAAVIVARTDPLGPVRTVHVTQASSSSVTITWTRVPGATGYRVSWHSAHGPEKSQL 730

Query: 2112 -VGQQMIFEEHGFRRTTP--------------PTTATPIRHRPRPYPPNVGQEALSQTT- 2155
              G+  + E  G    T               P  +  +R  P P       + L+ ++ 
Sbjct: 731  VSGEATVAELDGLEPDTEYTVHVRAHVAGVDGPPASVVVRTAPEPVGRVSRLQILNASSD 790

Query: 2156 ---ISWAPFQDTSEYIISCHPVGTDEEPLQFRV-PGTSTSATLTGLTRGATYNIIVEAL 2210
               I+W      + Y ++     ++  P++ ++ PG + SA + GL  G +Y++ V AL
Sbjct: 791  VLRITWVGVTGATAYRLAWG--RSEGGPMRHQILPGNTDSAEIRGLEGGVSYSVRVTAL 847



 Score =  111 bits (278), Expect = 8e-24
 Identities = 120/464 (25%), Positives = 195/464 (42%), Gaps = 67/464 (14%)

Query: 1804 PLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGP-----MKE 1858
            P+      +  AP DL  ++ +  SL  QWT  +  +TGY+V+ TP    G       +E
Sbjct: 223  PVTRPPDDSTSAPRDLVLSEPSSQSLRVQWTAASGPVTGYKVQYTPLTGLGQPLPSERQE 282

Query: 1859 INLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATE 1918
            +N+    +SV + GL   T+Y+V+V AL          G   T     P     + + T 
Sbjct: 283  VNVPAGETSVRLRGLRPLTEYQVTVIALYANSIGEAVSGTARTTALEGP--ELTIQNTTA 340

Query: 1919 TTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLN 1978
             ++ ++WR+     TG++V     +G    Q+ + P   S  +  L+PGTDY++ + TL 
Sbjct: 341  HSLLVAWRS-VPGATGYRVTWRVLSGGPTQQQELGPGQGSVLLRDLEPGTDYEVTVSTLF 399

Query: 1979 DNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQ-PPRARITGYIIKYEKPGS--PP 2035
              +      + A T       LR +   P S+L+SW   P AR  GY +++ +     PP
Sbjct: 400  GRSVGPATSLMARTDASVEQTLRPVILGPTSILLSWNLVPEAR--GYRLEWRRETGLEPP 457

Query: 2036 REVVPRPRPGVTEATITGLEPGTEY--TIYVIALKNNQKSEP------------------ 2075
            ++VV      VT   + GL+PGTEY  T+Y + L+ ++ + P                  
Sbjct: 458  QKVVLPS--DVTRYQLDGLQPGTEYRLTLYTL-LEGHEVATPATVVPTGPELPVSPVTDL 514

Query: 2076 ----LIGRKKTVQKTPFVTHPGYDTGNGIQLPGTSGQQPSV---GQQMIFEEHGFRRTTP 2128
                L G++  V  +P    PG  T   I +  T G + ++   G Q  F+    +    
Sbjct: 515  QATELPGQRVRVSWSPV---PGA-TQYRIIVRSTQGVERTLVLPGSQTAFDLDDVQAGLS 570

Query: 2129 PTTATPIRHRPR------------PYPP------NVGQEALSQTTISWAPFQDTSEYIIS 2170
             T     R  PR            P  P       V     ++  ++W P    S + IS
Sbjct: 571  YTVRVSARVGPREGSASVLTVRREPETPLAVPGLRVVVSDATRVRVAWGPVPGASGFRIS 630

Query: 2171 CHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQ 2214
                G+  E  Q  +P  ST+  +TGL  G TY + V  L+ ++
Sbjct: 631  WS-TGSGPESSQ-TLPPDSTATDITGLQPGTTYQVAVSVLRGRE 672


>gi|55743096 collagen, type XIV, alpha 1 [Homo sapiens]
          Length = 1796

 Score =  211 bits (537), Expect = 7e-54
 Identities = 246/1013 (24%), Positives = 420/1013 (41%), Gaps = 134/1013 (13%)

Query: 907  VPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTG 966
            V  P  L++  ++   + I W  P     GY++ V P +  G+  Q    +  T A + G
Sbjct: 30   VAPPTRLRYNVISHDSIQISWKAPRGKFGGYKLLVTPTS-GGKTNQLNLQNTATKAIIQG 88

Query: 967  LSPGVTYYFKVFAVSHGRESKPLTAQ----------------------QTTKLDAPTNLQ 1004
            L P   Y  ++ A +  +ESKP   Q                        ++  +P  ++
Sbjct: 89   LMPDQNYTVQIIAYNKDKESKPAQGQFRIKDLEKRKDPKPRVKVVDRGNGSRPSSPEEVK 148

Query: 1005 FVNET----DSTVLV--RWTPPRAQ-----------ITGYRLTVGLTRRGQPRQYNVGPS 1047
            FV +T    D  +LV   W+  R             +T + +    TR G   QY+  P 
Sbjct: 149  FVCQTPAIADIVILVDGSWSIGRFNFRLVRHFLENLVTAFDVGSEKTRIGLA-QYSGDPR 207

Query: 1048 VSKY------------PLRNLQPASEYTVSLVAIK---GNQESPKA---TGV------FT 1083
            +  +             +RNL      T++ +A+     N   P+A   TGV       T
Sbjct: 208  IEWHLNAFSTKDEVIEAVRNLPYKGGNTLTGLALNYIFENSFKPEAGSRTGVSKIGILIT 267

Query: 1084 TLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGL 1143
              +    I P +  + E+ + +         F +GV+ +   E  +E+ S+  S  V  +
Sbjct: 268  DGKSQDDIIPPSRNLRESGVEL---------FAIGVKNADVNEL-QEIASEPDSTHVYNV 317

Query: 1144 TPGVEYVYTI------QVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWER 1197
                + ++T+       +    +E+D  I         PPT L + +        V+W  
Sbjct: 318  AE-FDLMHTVVESLTRTLCSRVEEQDREIKASAHAITGPPTEL-ITSEVTARSFMVNWTH 375

Query: 1198 STTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESV 1257
            +   ++  YR+   PT G  G   E VV    SS    NL    EY ++V+ +     S 
Sbjct: 376  APG-NVEKYRVVYYPTRG--GKPDEVVVDGTVSSTVLKNLMSLTEYQIAVFAIYAHTASE 432

Query: 1258 PISDTIIP-EVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIFEDFV 1316
             +  T     +P  +DL   D+T++S+ ++W  +  ++  GY I      EG+    D  
Sbjct: 433  GLRGTETTLALPMASDLLLYDVTENSMRVKWDAVPGAS--GYLILYAPLTEGLA--GDEK 488

Query: 1317 DSSVGY----YTVTGLEPGIDYDISVITLINGGESAPTTLTQQT-AVPPPTDLRFTNIGP 1371
            +  +G       ++GL P  +Y ++V  +     S P T  + T A+ PP +LR +N+G 
Sbjct: 489  EMKIGETHTDIELSGLLPNTEYTVTVYAMFGEEASDPVTGQETTLALSPPRNLRISNVGS 548

Query: 1372 DTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSS 1431
            ++ R+TW  P S  +  + + Y+     E + E+ + P      L  L P TEY +++ S
Sbjct: 549  NSARLTW-DPTSRQINGYRIVYNNADGTE-INEVEVDPI-TTFPLKGLTPLTEYTIAIFS 605

Query: 1432 VYEQHESTPLRGRQKTG-LDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSG 1490
            +Y++ +S PL G   T  + +   ++  ++T +SF V W    A    +++   P  + G
Sbjct: 606  IYDEGQSEPLTGVFTTEEVPAQQYLEIDEVTTDSFRVTWHPLSADEGLHKLMWIPV-YGG 664

Query: 1491 RPREDRVPHSRNSITLTNLTPGTEYVVSIVA-LNGREESPLLIGQQSTVSD--------- 1540
            +  E  +   ++S  +  L PGTEY VS++A L+   ES ++    +T+           
Sbjct: 665  KTEEVVLKEEQDSHVIEGLEPGTEYEVSLLAVLDDGSESEVVTAVGTTLDSFWTEPATTI 724

Query: 1541 VP------------RDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFT-- 1586
            VP            R+L V   T +SL + WD     V+ +R+TY    G+ P +E    
Sbjct: 725  VPTTSVTSVFQTGIRNLVVGDETTSSLRVKWDISDSDVQQFRVTYMTAQGD-PEEEVIGT 783

Query: 1587 --VPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDV 1644
              VPGS++   +  L P  +Y +TV  +   G+  + S P           P  ++V++ 
Sbjct: 784  VMVPGSQNNLLLKPLLPDTEYKVTVTPIYTDGEGVSVSAP---GKTLPSSGPQNLRVSEE 840

Query: 1645 QDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVY 1704
              N + + W P SSPV GYR+   P + PGPT     G D   + I  L   ++Y V ++
Sbjct: 841  WYNRLRITWDPPSSPVKGYRIVYKPVSVPGPTLETFVGADINTILITNLLSGMDYNVKIF 900

Query: 1705 AQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGI 1764
            A   SG S  L     T       L    V++ S+   W+  +   + YRV   S +D  
Sbjct: 901  ASQASGFSDALTGMVKTLFLGVTNLQAKHVEMTSLCAHWQVHR-HATAYRVVIESLQDRQ 959

Query: 1765 HELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPT 1817
             +      G        GL+P SEY +SV     ++E  P +         PT
Sbjct: 960  KQESTVGGGTTRHC-FYGLQPDSEYKISVYTKLQEIEG-PSVSIMEKTQSLPT 1010



 Score =  208 bits (529), Expect = 6e-53
 Identities = 169/651 (25%), Positives = 298/651 (45%), Gaps = 50/651 (7%)

Query: 1360 PPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNL 1419
            PPT+L  + +   +  V W   P  ++  + V Y P +  +   E+ +  + ++ VL NL
Sbjct: 355  PPTELITSEVTARSFMVNWTHAPG-NVEKYRVVYYPTRGGKP-DEVVVDGTVSSTVLKNL 412

Query: 1420 LPGTEYVVSVSSVYEQHESTPLRGRQKT-GLDSPTGIDFSDITANSFTVHWIAPRATITG 1478
            +  TEY ++V ++Y    S  LRG + T  L   + +   D+T NS  V W A     +G
Sbjct: 413  MSLTEYQIAVFAIYAHTASEGLRGTETTLALPMASDLLLYDVTENSMRVKWDAVPGA-SG 471

Query: 1479 YRIRHHP--EHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQS 1536
            Y I + P  E  +G  +E ++  +   I L+ L P TEY V++ A+ G E S  + GQ++
Sbjct: 472  YLILYAPLTEGLAGDEKEMKIGETHTDIELSGLLPNTEYTVTVYAMFGEEASDPVTGQET 531

Query: 1537 TVS-DVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTAT 1595
            T++   PR+L +      S  ++WD  +  +  YRI Y    G   + E  V    +T  
Sbjct: 532  TLALSPPRNLRISNVGSNSARLTWDPTSRQINGYRIVYNNADGTE-INEVEVDPI-TTFP 589

Query: 1596 ISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQ--MQVTDVQDNSISVKW 1653
            + GL P  +YTI ++++   G S    +P++  + TE + P+Q  +++ +V  +S  V W
Sbjct: 590  LKGLTPLTEYTIAIFSIYDEGQS----EPLTGVFTTE-EVPAQQYLEIDEVTTDSFRVTW 644

Query: 1654 LPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQ 1713
             P S+    +++   P  G G T+      +Q    IEGL+P  EY VS+ A    G   
Sbjct: 645  HPLSADEGLHKLMWIPVYG-GKTEEVVLKEEQDSHVIEGLEPGTEYEVSLLAVLDDGSES 703

Query: 1714 PLVQTAVTNIDR----------------------PKGLAFTDVDVDSIKIAWESPQGQVS 1751
             +V    T +D                        + L   D    S+++ W+     V 
Sbjct: 704  EVVTAVGTTLDSFWTEPATTIVPTTSVTSVFQTGIRNLVVGDETTSSLRVKWDISDSDVQ 763

Query: 1752 RYRVTYSS----PEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIG 1807
            ++RVTY +    PE+ +      P G ++   L+ L P +EY V+V  ++ D E   +  
Sbjct: 764  QFRVTYMTAQGDPEEEVIGTVMVP-GSQNNLLLKPLLPDTEYKVTVTPIYTDGEGVSVSA 822

Query: 1808 TQSTAIPA--PTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDS 1865
               T +P+  P +L+ ++     L   W PP+  + GYR+   P    GP  E  +  D 
Sbjct: 823  PGKT-LPSSGPQNLRVSEEWYNRLRITWDPPSSPVKGYRIVYKPVSVPGPTLETFVGADI 881

Query: 1866 SSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISW 1925
            ++++++ L+    Y V ++A + +  S    G+V TL       +A+  +   T++   W
Sbjct: 882  NTILITNLLSGMDYNVKIFASQASGFSDALTGMVKTLFLGVTNLQAKHVEM--TSLCAHW 939

Query: 1926 RTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYT 1976
            +      T ++V       +   + T+      +   GLQP ++YKI +YT
Sbjct: 940  QVHRHA-TAYRVVIESLQDRQKQESTVGGGTTRHCFYGLQPDSEYKISVYT 989



 Score =  183 bits (465), Expect = 2e-45
 Identities = 174/687 (25%), Positives = 291/687 (42%), Gaps = 54/687 (7%)

Query: 795  EDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSST 854
            E+ ++ +  S    T P  P +    +V   S +V W+     +  YR+VY P+  G   
Sbjct: 339  EEQDREIKASAHAITGP--PTELITSEVTARSFMVNWTHAPGNVEKYRVVYYPTRGGKPD 396

Query: 855  ELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQ 914
            E+ +  T +S  L +L    +Y I ++A+  +  S      +   GT  +  +P   DL 
Sbjct: 397  EVVVDGTVSSTVLKNLMSLTEYQIAVFAIYAHTAS------EGLRGTETTLALPMASDLL 450

Query: 915  FVEVTDVKVTIMWTPPESAVTGYRVDVIPV--NLPGEHGQRLPISRNTFAEVTGLSPGVT 972
              +VT+  + + W     A +GY +   P+   L G+  +      +T  E++GL P   
Sbjct: 451  LYDVTENSMRVKWDAVPGA-SGYLILYAPLTEGLAGDEKEMKIGETHTDIELSGLLPNTE 509

Query: 973  YYFKVFAVSHGRESKPLTAQQTT-KLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTV 1031
            Y   V+A+     S P+T Q+TT  L  P NL+  N   ++  + W P   QI GYR+  
Sbjct: 510  YTVTVYAMFGEEASDPVTGQETTLALSPPRNLRISNVGSNSARLTWDPTSRQINGYRIVY 569

Query: 1032 GLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSI 1091
                  +  +  V P ++ +PL+ L P +EYT+++ +I    +S   TGVFTT +  +  
Sbjct: 570  NNADGTEINEVEVDP-ITTFPLKGLTPLTEYTIAIFSIYDEGQSEPLTGVFTTEEVPAQQ 628

Query: 1092 PPYNTEVTETTIVITWTP--APRIGFKLGVRPSQGGEAPREV-TSDSGSIVVSGLTPGVE 1148
                 EVT  +  +TW P  A     KL   P  GG+    V   +  S V+ GL PG E
Sbjct: 629  YLEIDEVTTDSFRVTWHPLSADEGLHKLMWIPVYGGKTEEVVLKEEQDSHVIEGLEPGTE 688

Query: 1149 Y-VYTIQVLRDGQERDAPIV---------NKVVTPLSPPTNLH----------LEANPDT 1188
            Y V  + VL DG E +              +  T + P T++           +  +  T
Sbjct: 689  YEVSLLAVLDDGSESEVVTAVGTTLDSFWTEPATTIVPTTSVTSVFQTGIRNLVVGDETT 748

Query: 1189 GVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEV-----VHADQSSCTFDNLSPGLEY 1243
              L V W+ S + D+  +R+T       QG+  EEV     V   Q++     L P  EY
Sbjct: 749  SSLRVKWDISDS-DVQQFRVTYMTA---QGDPEEEVIGTVMVPGSQNNLLLKPLLPDTEY 804

Query: 1244 NVSVYTVKDDKESVPIS---DTIIPEVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGYRI 1300
             V+V  +  D E V +S    T+    PQ  +L   +   + + + W P  SS + GYRI
Sbjct: 805  KVTVTPIYTDGEGVSVSAPGKTLPSSGPQ--NLRVSEEWYNRLRITWDP-PSSPVKGYRI 861

Query: 1301 TVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAVPP 1360
                     P  E FV + +    +T L  G+DY++ +      G S   T   +T    
Sbjct: 862  VYKPVSVPGPTLETFVGADINTILITNLLSGMDYNVKIFASQASGFSDALTGMVKTLFLG 921

Query: 1361 PTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLL 1420
             T+L+  ++   ++   W           ++     + ++   E ++           L 
Sbjct: 922  VTNLQAKHVEMTSLCAHWQVHRHATAYRVVIESLQDRQKQ---ESTVGGGTTRHCFYGLQ 978

Query: 1421 PGTEYVVSVSSVYEQHESTPLRGRQKT 1447
            P +EY +SV +  ++ E   +   +KT
Sbjct: 979  PDSEYKISVYTKLQEIEGPSVSIMEKT 1005



 Score =  181 bits (458), Expect = 1e-44
 Identities = 170/702 (24%), Positives = 295/702 (42%), Gaps = 72/702 (10%)

Query: 1430 SSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFS 1489
            S V EQ           TG   PT +  S++TA SF V+W      +  YR+ ++P    
Sbjct: 336  SRVEEQDREIKASAHAITG--PPTELITSEVTARSFMVNWTHAPGNVEKYRVVYYPTR-G 392

Query: 1490 GRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVS-DVPRDLEVV 1548
            G+P E  V  + +S  L NL   TEY +++ A+     S  L G ++T++  +  DL + 
Sbjct: 393  GKPDEVVVDGTVSSTVLKNLMSLTEYQIAVFAIYAHTASEGLRGTETTLALPMASDLLLY 452

Query: 1549 AATPTSLLISWDA----PAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVD 1604
              T  S+ + WDA        + Y  +T G  G     +E  +  + +   +SGL P  +
Sbjct: 453  DVTENSMRVKWDAVPGASGYLILYAPLTEGLAGDE---KEMKIGETHTDIELSGLLPNTE 509

Query: 1605 YTITVYAVTGRGDSPASSKPISINYRT-EIDKPSQMQVTDVQDNSISVKWLPSSSPVTGY 1663
            YT+TVYA+ G      +S P++    T  +  P  +++++V  NS  + W P+S  + GY
Sbjct: 510  YTVTVYAMFGE----EASDPVTGQETTLALSPPRNLRISNVGSNSARLTWDPTSRQINGY 565

Query: 1664 RVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTN- 1722
            R+     N  G    +      T   ++GL P  EY +++++    G+S+PL     T  
Sbjct: 566  RIVYN--NADGTEINEVEVDPITTFPLKGLTPLTEYTIAIFSIYDEGQSEPLTGVFTTEE 623

Query: 1723 IDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAP----------- 1771
            +   + L   +V  DS ++ W               S ++G+H+L   P           
Sbjct: 624  VPAQQYLEIDEVTTDSFRVTWHP------------LSADEGLHKLMWIPVYGGKTEEVVL 671

Query: 1772 DGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAI------PAPTDLKFTQVT 1825
              E+D+  ++GL PG+EY VS++A+ DD     ++    T +      PA T +  T VT
Sbjct: 672  KEEQDSHVIEGLEPGTEYEVSLLAVLDDGSESEVVTAVGTTLDSFWTEPATTIVPTTSVT 731

Query: 1826 P----------------TSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEIN--LAPDS-S 1866
                             +SL  +W   +  +  +RV     +     + I   + P S +
Sbjct: 732  SVFQTGIRNLVVGDETTSSLRVKWDISDSDVQQFRVTYMTAQGDPEEEVIGTVMVPGSQN 791

Query: 1867 SVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWR 1926
            ++++  L+  T+Y+V+V  +              TL + S P+  RV++     + I+W 
Sbjct: 792  NLLLKPLLPDTEYKVTVTPIYTDGEGVSVSAPGKTLPS-SGPQNLRVSEEWYNRLRITWD 850

Query: 1927 TKTETITGFQVDAVPANGQTPIQRT-IKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSP 1985
              +  + G+++   P +   P   T +  D+ +  IT L  G DY + ++    +  S  
Sbjct: 851  PPSSPVKGYRIVYKPVSVPGPTLETFVGADINTILITNLLSGMDYNVKIFASQASGFSDA 910

Query: 1986 VVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPG 2045
            +     T     +NL+       SL   WQ  R   T Y +  E      ++       G
Sbjct: 911  LTGMVKTLFLGVTNLQAKHVEMTSLCAHWQVHR-HATAYRVVIESLQDRQKQ-ESTVGGG 968

Query: 2046 VTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQKTP 2087
             T     GL+P +EY I V   K  +   P +   +  Q  P
Sbjct: 969  TTRHCFYGLQPDSEYKISVYT-KLQEIEGPSVSIMEKTQSLP 1009



 Score =  171 bits (434), Expect = 6e-42
 Identities = 167/672 (24%), Positives = 288/672 (42%), Gaps = 57/672 (8%)

Query: 729  TEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIV 788
            +E+TA SF+V+W  A   V  +RV Y     G +P  + +  T +S  + +L+   +Y +
Sbjct: 362  SEVTARSFMVNWTHAPGNVEKYRVVY-YPTRGGKPDEVVVDGTVSSTVLKNLMSLTEYQI 420

Query: 789  NVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPS 848
             V+ I        +  T  T A     D  +  V + S+ V+W       +GY I+Y+P 
Sbjct: 421  AVFAIYAHTASEGLRGTETTLALPMASDLLLYDVTENSMRVKWDAVPG-ASGYLILYAPL 479

Query: 849  VE---GSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSD 905
             E   G   E+ + ET   + LS L P  +Y +T+YA+   + S PV  Q+ T       
Sbjct: 480  TEGLAGDEKEMKIGETHTDIELSGLLPNTEYTVTVYAMFGEEASDPVTGQETTL------ 533

Query: 906  TVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVT 965
             +  PR+L+   V      + W P    + GYR  ++  N  G     + +   T   + 
Sbjct: 534  ALSPPRNLRISNVGSNSARLTWDPTSRQINGYR--IVYNNADGTEINEVEVDPITTFPLK 591

Query: 966  GLSPGVTYYFKVFAVSHGRESKPLTAQQTT-KLDAPTNLQFVNETDSTVLVRWTPPRAQI 1024
            GL+P   Y   +F++    +S+PLT   TT ++ A   L+    T  +  V W P  A  
Sbjct: 592  GLTPLTEYTIAIFSIYDEGQSEPLTGVFTTEEVPAQQYLEIDEVTTDSFRVTWHPLSADE 651

Query: 1025 TGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAI-KGNQESPKATGVFT 1083
              ++L       G+  +  +      + +  L+P +EY VSL+A+     ES   T V T
Sbjct: 652  GLHKLMWIPVYGGKTEEVVLKEEQDSHVIEGLEPGTEYEVSLLAVLDDGSESEVVTAVGT 711

Query: 1084 TL-----QPGSSIPPYNT---------------EVTETTIVITW--TPAPRIGFKLGVRP 1121
            TL     +P ++I P  +               + T +++ + W  + +    F++    
Sbjct: 712  TLDSFWTEPATTIVPTTSVTSVFQTGIRNLVVGDETTSSLRVKWDISDSDVQQFRVTYMT 771

Query: 1122 SQGGEAPRE-------VTSDSGSIVVSGLTPGVEYVYTI-QVLRDGQERDAPIVNKVVTP 1173
            +QG   P E       V     ++++  L P  EY  T+  +  DG+        K + P
Sbjct: 772  AQGD--PEEEVIGTVMVPGSQNNLLLKPLLPDTEYKVTVTPIYTDGEGVSVSAPGKTL-P 828

Query: 1174 LSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCT 1233
             S P NL + +      L ++W+  ++P + GYRI   P +   G +LE  V AD ++  
Sbjct: 829  SSGPQNLRV-SEEWYNRLRITWDPPSSP-VKGYRIVYKPVS-VPGPTLETFVGADINTIL 885

Query: 1234 FDNLSPGLEYNVSVYTVKDDKESVPISDTIIPEVPQLTDLSFVDITDSSIGLRWTPLNSS 1293
              NL  G++YNV ++  +    S  ++  +      +T+L    +  +S+   W     +
Sbjct: 886  ITNLLSGMDYNVKIFASQASGFSDALTGMVKTLFLGVTNLQAKHVEMTSLCAHWQVHRHA 945

Query: 1294 TIIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTL- 1352
            T   YR+ V+ + +     E  V      +   GL+P  +Y ISV T +   E    ++ 
Sbjct: 946  T--AYRV-VIESLQDRQKQESTVGGGTTRHCFYGLQPDSEYKISVYTKLQEIEGPSVSIM 1002

Query: 1353 --TQQTAVPPPT 1362
              TQ     PPT
Sbjct: 1003 EKTQSLPTRPPT 1014



 Score =  140 bits (354), Expect = 1e-32
 Identities = 142/603 (23%), Positives = 244/603 (40%), Gaps = 86/603 (14%)

Query: 1636 PSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQP 1695
            P+++  ++V   S  V W  +   V  YRV   P  G  P +    G   + + ++ L  
Sbjct: 356  PTELITSEVTARSFMVNWTHAPGNVEKYRVVYYPTRGGKPDEVVVDGTVSSTV-LKNLMS 414

Query: 1696 TVEYVVSVYAQNPSGESQPLVQTAVT-NIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYR 1754
              EY ++V+A      S+ L  T  T  +     L   DV  +S+++ W++  G  S Y 
Sbjct: 415  LTEYQIAVFAIYAHTASEGLRGTETTLALPMASDLLLYDVTENSMRVKWDAVPG-ASGYL 473

Query: 1755 VTYSSPEDGIH-ELFPAPDGEEDT-AELQGLRPGSEYTVSVVALHDDMESQPLIGTQST- 1811
            + Y+   +G+  +      GE  T  EL GL P +EYTV+V A+  +  S P+ G ++T 
Sbjct: 474  ILYAPLTEGLAGDEKEMKIGETHTDIELSGLLPNTEYTVTVYAMFGEEASDPVTGQETTL 533

Query: 1812 AIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVS 1871
            A+  P +L+ + V   S    W P + Q+ GYR+     + T  + E+ + P  ++  + 
Sbjct: 534  ALSPPRNLRISNVGSNSARLTWDPTSRQINGYRIVYNNADGT-EINEVEVDP-ITTFPLK 591

Query: 1872 GLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTET 1931
            GL   T+Y ++++++ D   S P  GV TT E V   +   + + T  +  ++W   +  
Sbjct: 592  GLTPLTEYTIAIFSIYDEGQSEPLTGVFTT-EEVPAQQYLEIDEVTTDSFRVTWHPLSAD 650

Query: 1932 ITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDAS 1991
                ++  +P  G    +  +K +  S+ I GL+PGT+Y++ L  + D+   S VV    
Sbjct: 651  EGLHKLMWIPVYGGKTEEVVLKEEQDSHVIEGLEPGTEYEVSLLAVLDDGSESEVVTAVG 710

Query: 1992 TAIDA-------------------PSNLRFLAT---TPNSLLVSWQPPRARITGYIIKY- 2028
            T +D+                    + +R L     T +SL V W    + +  + + Y 
Sbjct: 711  TTLDSFWTEPATTIVPTTSVTSVFQTGIRNLVVGDETTSSLRVKWDISDSDVQQFRVTYM 770

Query: 2029 EKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLI-GRKKTVQKTP 2087
               G P  EV+                     T+ V   +NN   +PL+   +  V  TP
Sbjct: 771  TAQGDPEEEVIG--------------------TVMVPGSQNNLLLKPLLPDTEYKVTVTP 810

Query: 2088 FVTHPGYDTGNGIQLPGTSGQQPSVGQQMIFEEHGFRRTTPPTTATPIRHRPRPYPPNVG 2147
                  Y  G G+ +       PS G Q +                            V 
Sbjct: 811  I-----YTDGEGVSVSAPGKTLPSSGPQNL---------------------------RVS 838

Query: 2148 QEALSQTTISW-APFQDTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNII 2206
            +E  ++  I+W  P      Y I   PV      L+  V     +  +T L  G  YN+ 
Sbjct: 839  EEWYNRLRITWDPPSSPVKGYRIVYKPVSVPGPTLETFVGADINTILITNLLSGMDYNVK 898

Query: 2207 VEA 2209
            + A
Sbjct: 899  IFA 901



 Score =  100 bits (248), Expect = 2e-20
 Identities = 130/581 (22%), Positives = 232/581 (39%), Gaps = 53/581 (9%)

Query: 624  NSHPIQWNAPQPSHISKYILRWRP--KNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQL 681
            NS  ++W+A   +  S Y++ + P  +   G  KE  I        + GL P   Y    
Sbjct: 457  NSMRVKWDAVPGA--SGYLILYAPLTEGLAGDEKEMKIGETHTDIELSGLLPNTEYT--- 511

Query: 682  ISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWV 741
                      VT +       S PVT    T   +P   L      ++ + ++S  ++W 
Sbjct: 512  ----------VTVYAMFGEEASDPVTGQETTLALSPPRNL-----RISNVGSNSARLTWD 556

Query: 742  SASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSL 801
              S  ++G+R+ Y  + +G E   +++    T+  +  L P  +Y + ++ I ++G+   
Sbjct: 557  PTSRQINGYRIVYN-NADGTEINEVEV-DPITTFPLKGLTPLTEYTIAIFSIYDEGQSEP 614

Query: 802  ILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPET 861
            +     T    A     +D+V   S  V W    A    +++++ P   G + E+ L E 
Sbjct: 615  LTGVFTTEEVPAQQYLEIDEVTTDSFRVTWHPLSADEGLHKLMWIPVYGGKTEEVVLKEE 674

Query: 862  ANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETT-----GTPRSDTVPSP------ 910
             +S  +  L+PG +Y +++ AV ++   + VV    TT       P +  VP+       
Sbjct: 675  QDSHVIEGLEPGTEYEVSLLAVLDDGSESEVVTAVGTTLDSFWTEPATTIVPTTSVTSVF 734

Query: 911  ----RDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEH----GQRLPISRNTFA 962
                R+L   + T   + + W   +S V  +RV  +      E        +P S+N   
Sbjct: 735  QTGIRNLVVGDETTSSLRVKWDISDSDVQQFRVTYMTAQGDPEEEVIGTVMVPGSQNNLL 794

Query: 963  EVTGLSPGVTYYFKVFAVSHGRESKPLTAQ-QTTKLDAPTNLQFVNETDSTVLVRWTPPR 1021
             +  L P   Y   V  +    E   ++A  +T     P NL+   E  + + + W PP 
Sbjct: 795  -LKPLLPDTEYKVTVTPIYTDGEGVSVSAPGKTLPSSGPQNLRVSEEWYNRLRITWDPPS 853

Query: 1022 AQITGYRLTV-GLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATG 1080
            + + GYR+    ++  G   +  VG  ++   + NL    +Y V + A + +  S   TG
Sbjct: 854  SPVKGYRIVYKPVSVPGPTLETFVGADINTILITNLLSGMDYNVKIFASQASGFSDALTG 913

Query: 1081 VFTTLQPG-SSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSI- 1138
            +  TL  G +++   + E+  T++   W           V  S      +E T   G+  
Sbjct: 914  MVKTLFLGVTNLQAKHVEM--TSLCAHWQVHRHATAYRVVIESLQDRQKQESTVGGGTTR 971

Query: 1139 -VVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPT 1178
                GL P  E  Y I V    QE + P V+ +    S PT
Sbjct: 972  HCFYGLQPDSE--YKISVYTKLQEIEGPSVSIMEKTQSLPT 1010



 Score = 64.7 bits (156), Expect = 1e-09
 Identities = 59/252 (23%), Positives = 106/252 (42%), Gaps = 36/252 (14%)

Query: 1856 MKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLEN----------- 1904
            ++EI   PDS+ V          Y V+ + L  T+     + + + +E            
Sbjct: 302  LQEIASEPDSTHV----------YNVAEFDLMHTVVESLTRTLCSRVEEQDREIKASAHA 351

Query: 1905 -VSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITG 1963
               PP     ++ T  +  ++W      +  ++V   P  G  P +  +   V S  +  
Sbjct: 352  ITGPPTELITSEVTARSFMVNWTHAPGNVEKYRVVYYPTRGGKPDEVVVDGTVSSTVLKN 411

Query: 1964 LQPGTDYK-----IYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQP-P 2017
            L   T+Y+     IY +T ++  R +    + + A+   S+L     T NS+ V W   P
Sbjct: 412  LMSLTEYQIAVFAIYAHTASEGLRGT----ETTLALPMASDLLLYDVTENSMRVKWDAVP 467

Query: 2018 RARITGYIIKYE--KPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEP 2075
             A  +GY+I Y     G    E   +     T+  ++GL P TEYT+ V A+   + S+P
Sbjct: 468  GA--SGYLILYAPLTEGLAGDEKEMKIGETHTDIELSGLLPNTEYTVTVYAMFGEEASDP 525

Query: 2076 LIGRKKTVQKTP 2087
            + G++ T+  +P
Sbjct: 526  VTGQETTLALSP 537



 Score = 53.1 bits (126), Expect = 3e-06
 Identities = 31/106 (29%), Positives = 51/106 (48%), Gaps = 4/106 (3%)

Query: 1813 IPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSG 1872
            +  PT L++  ++  S+   W  P  +  GY++ VTP    G   ++NL   ++  ++ G
Sbjct: 30   VAPPTRLRYNVISHDSIQISWKAPRGKFGGYKLLVTPTSG-GKTNQLNLQNTATKAIIQG 88

Query: 1873 LMVATKYEVSVYALKDTLTSRPAQGV--VTTLENVSPPR-RARVTD 1915
            LM    Y V + A      S+PAQG   +  LE    P+ R +V D
Sbjct: 89   LMPDQNYTVQIIAYNKDKESKPAQGQFRIKDLEKRKDPKPRVKVVD 134



 Score = 50.1 bits (118), Expect = 3e-05
 Identities = 21/70 (30%), Positives = 36/70 (51%)

Query: 822 VDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIY 881
           +   SI + W  P+    GY+++ +P+  G + +LNL  TA    +  L P   Y + I 
Sbjct: 41  ISHDSIQISWKAPRGKFGGYKLLVTPTSGGKTNQLNLQNTATKAIIQGLMPDQNYTVQII 100

Query: 882 AVEENQESTP 891
           A  +++ES P
Sbjct: 101 AYNKDKESKP 110



 Score = 45.8 bits (107), Expect = 5e-04
 Identities = 23/83 (27%), Positives = 39/83 (46%), Gaps = 1/83 (1%)

Query: 1632 EIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIE 1691
            ++  P++++   +  +SI + W        GY++  TP +G G T         T+  I+
Sbjct: 29   QVAPPTRLRYNVISHDSIQISWKAPRGKFGGYKLLVTPTSG-GKTNQLNLQNTATKAIIQ 87

Query: 1692 GLQPTVEYVVSVYAQNPSGESQP 1714
            GL P   Y V + A N   ES+P
Sbjct: 88   GLMPDQNYTVQIIAYNKDKESKP 110



 Score = 45.8 bits (107), Expect = 5e-04
 Identities = 31/107 (28%), Positives = 52/107 (48%), Gaps = 5/107 (4%)

Query: 1997 PSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEP 2056
            P+ LR+   + +S+ +SW+ PR +  GY +    P S  +      +   T+A I GL P
Sbjct: 33   PTRLRYNVISHDSIQISWKAPRGKFGGYKLLVT-PTSGGKTNQLNLQNTATKAIIQGLMP 91

Query: 2057 GTEYTIYVIALKNNQKSEPLIGRKK----TVQKTPFVTHPGYDTGNG 2099
               YT+ +IA   +++S+P  G+ +      +K P       D GNG
Sbjct: 92   DQNYTVQIIAYNKDKESKPAQGQFRIKDLEKRKDPKPRVKVVDRGNG 138



 Score = 41.6 bits (96), Expect = 0.010
 Identities = 21/81 (25%), Positives = 35/81 (43%)

Query: 1905 VSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGL 1964
            V+PP R R    +  +I ISW+       G+++   P +G    Q  ++       I GL
Sbjct: 30   VAPPTRLRYNVISHDSIQISWKAPRGKFGGYKLLVTPTSGGKTNQLNLQNTATKAIIQGL 89

Query: 1965 QPGTDYKIYLYTLNDNARSSP 1985
             P  +Y + +   N +  S P
Sbjct: 90   MPDQNYTVQIIAYNKDKESKP 110



 Score = 38.9 bits (89), Expect = 0.062
 Identities = 21/90 (23%), Positives = 43/90 (47%), Gaps = 2/90 (2%)

Query: 1355 QTAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAV 1414
            Q  V PPT LR+  I  D+++++W  P       + +  +P    +   +L++  +    
Sbjct: 27   QGQVAPPTRLRYNVISHDSIQISWKAPRG-KFGGYKLLVTPTSGGK-TNQLNLQNTATKA 84

Query: 1415 VLTNLLPGTEYVVSVSSVYEQHESTPLRGR 1444
            ++  L+P   Y V + +  +  ES P +G+
Sbjct: 85   IIQGLMPDQNYTVQIIAYNKDKESKPAQGQ 114



 Score = 32.3 bits (72), Expect = 5.8
 Identities = 31/123 (25%), Positives = 52/123 (42%), Gaps = 11/123 (8%)

Query: 731 ITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNV 790
           I+  S  +SW +      G+++    +  G   Q L+L +TAT   I  L+P + Y V +
Sbjct: 41  ISHDSIQISWKAPRGKFGGYKLLVTPTSGGKTNQ-LNLQNTATKAIIQGLMPDQNYTVQI 99

Query: 791 YQISEDGEQSLILSTSQTTAPD----APPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYS 846
              ++D E     +  Q    D      P P V  VD  +     SRP +P     +  +
Sbjct: 100 IAYNKDKESK--PAQGQFRIKDLEKRKDPKPRVKVVDRGN----GSRPSSPEEVKFVCQT 153

Query: 847 PSV 849
           P++
Sbjct: 154 PAI 156


>gi|157952215 protein tyrosine phosphatase, receptor type, B isoform a
            [Homo sapiens]
          Length = 2215

 Score =  187 bits (476), Expect = 8e-47
 Identities = 273/1275 (21%), Positives = 508/1275 (39%), Gaps = 88/1275 (6%)

Query: 768  LPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSI 827
            + +T    N+ DL  G  Y  N   IS D E++++L T     P A    + ++   TS+
Sbjct: 291  IDNTTYGCNLQDLQAGTIY--NFRIISLDEERTVVLQTDPL--PPARFGVSKEKTTSTSL 346

Query: 828  VVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETA--NSVTLSDLQPGVQYNITIYAVEE 885
             V W+     +T Y +            + + E+   N  T  +L  G +YNI I AV  
Sbjct: 347  HVWWTPSSGKVTSYEVQLFDENNQKIQGVQIQESTSWNEYTFFNLTAGSKYNIAITAVSG 406

Query: 886  NQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVN 945
             + S  V     T G+    TVPSP     +      + I W+     V  YR+ ++   
Sbjct: 407  GKRSFSVY----TNGS----TVPSPVKDIGISTKANSLLISWSHGSGNVERYRLMLMDKG 458

Query: 946  LPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQF 1005
            +   HG  +     ++A   GL+PG  Y   V   + G ++      +T  ++  +NL+ 
Sbjct: 459  IL-VHGGVVDKHATSYA-FHGLTPGYLYNLTVMTEAAGLQNYRWKLVRTAPMEV-SNLKV 515

Query: 1006 VNETDSTVL-VRWTPPRAQITGYRLTVGLTRRGQPRQYNV-GPSVSKYPLRNLQPASEYT 1063
             N+   T L V+W  P   +  Y +T  L+ +G  ++  V  P +++   + L P   Y 
Sbjct: 516  TNDGSLTSLKVKWQRPPGNVDSYNIT--LSHKGTIKESRVLAPWITETHFKELVPGRLYQ 573

Query: 1064 VSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGV---- 1119
            V++  + G   + K   V  T     +    N      ++V++W+P      +  +    
Sbjct: 574  VTVSCVSGELSAQKMA-VGRTFPDKVANLEANNNGRMRSLVVSWSPPAGDWEQYRILLFN 632

Query: 1120 ------RPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTP 1173
                    + G E  + V  D+G      L PG +Y   + ++  G  +++        P
Sbjct: 633  DSVVLLNITVGKEETQYVMDDTG------LVPGRQYEVEV-IVESGNLKNSERCQGRTVP 685

Query: 1174 LSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCT 1233
            L+        AN  +  L++ W+   TP +  +         +    + + +  D    T
Sbjct: 686  LAVLQLRVKHANETS--LSIMWQ---TP-VAEWEKYIISLADRDLLLIHKSLSKDAKEFT 739

Query: 1234 FDNLSPGLEYNVSVYTVKDD-KESVPISDTIIPEVPQLTDLSFVDI-TDSSIGLRWTPLN 1291
            F +L PG +Y  +V ++  D K S  +    +P   Q+TDL   +    SS+   WT   
Sbjct: 740  FTDLVPGRKYMATVTSISGDLKNSSSVKGRTVPA--QVTDLHVANQGMTSSLFTNWTQAQ 797

Query: 1292 SSTIIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTT 1351
                  Y++ ++   E + I  + + S    Y+   L+ G  Y + V+T ++GG S+   
Sbjct: 798  GDVEF-YQVLLIH--ENVVIKNESISSETSRYSFHSLKSGSLYSV-VVTTVSGGISSRQV 853

Query: 1352 LTQQTAVPPPTD-LRFTNIGP-DTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISP 1409
            + +   VP     +   N G  D + V+W   P  D+ N+ V  S   + + V  L I+ 
Sbjct: 854  VVEGRTVPSSVSGVTVNNSGRNDYLSVSWLLAPG-DVDNYEVTLS--HDGKVVQSLVIAK 910

Query: 1410 SDNAVVLTNLLPGTEYVVSV---SSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFT 1466
            S      ++L PG  Y V++   S  YE H  +    +++T  D   G+  S+   + + 
Sbjct: 911  SVRECSFSSLTPGRLYTVTITTRSGKYENHSFS----QERTVPDKVQGVSVSNSARSDYL 966

Query: 1467 -VHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGR 1525
             V W+        Y +    ++   + +   +P S N      L PG  Y V++   +G+
Sbjct: 967  RVSWVHATGDFDHYEVTIKNKNNFIQTKS--IPKSENECVFVQLVPGRLYSVTVTTKSGQ 1024

Query: 1526 EESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRIT--YGETGGNSPVQ 1583
             E+    G   T+ +  +DL +   +   L ++W      V  Y I   + +     P  
Sbjct: 1025 YEANEQ-GNGRTIPEPVKDLTLRNRSTEDLHVTWSGANGDVDQYEIQLLFNDMKVFPP-- 1081

Query: 1584 EFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTD 1643
             F +  + +    + L PG  Y I V  ++G     A  +  ++    +    S    TD
Sbjct: 1082 -FHLVNTATEYRFTSLTPGRQYKILVLTISGDVQQSAFIEGFTVPSAVKNIHISPNGATD 1140

Query: 1644 VQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSV 1703
                S++V W P    V  Y V+    +      ++T      E T   L+   +Y + +
Sbjct: 1141 ----SLTVNWTPGGGDVDSYTVSAFRHSQK--VDSQTIPKHVFEHTFHRLEAGEQYQIMI 1194

Query: 1704 YAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDG 1763
             + + S ++Q  V            +A       S+ ++W+   G   RY +   + E+G
Sbjct: 1195 ASVSGSLKNQINVVGRTVPASVQGVIADNAYSSYSLIVSWQKAAGVAERYDILLLT-ENG 1253

Query: 1764 IHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQ 1823
            I     +        + + L PG +Y + ++ +   + S+       T   A TDL+ T+
Sbjct: 1254 ILLRNTSEPATTKQHKFEDLTPGKKYKIQILTVSGGLFSKEAQTEGRTVPAAVTDLRITE 1313

Query: 1824 VTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKE-INLAPDSSSVVVSGLMVATKYEVS 1882
             +   LS +WT    +L+ Y + +   +  G ++E   + P   S     L+    Y++ 
Sbjct: 1314 NSTRHLSFRWTASEGELSWYNIFLYNPD--GNLQERAQVDPLVQSFSFQNLLQGRMYKMV 1371

Query: 1883 VYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPA 1942
            +      L++       T   +VS  R +     T  ++  +W   +     +++     
Sbjct: 1372 IVTHSGELSNESFIFGRTVPASVSHLRGSNRN--TTDSLWFNWSPASGDFDFYELILYNP 1429

Query: 1943 NGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRF 2002
            NG T  +     D+  +   GL PG  Y +++ T +    S+ V  ++ TA   PS + F
Sbjct: 1430 NG-TKKENWKDKDLTEWRFQGLVPGRKYVLWVVT-HSGDLSNKVTAESRTAPSPPSLMSF 1487

Query: 2003 LATTPNSLLVSWQPP 2017
                  SL ++W+ P
Sbjct: 1488 ADIANTSLAITWKGP 1502



 Score =  169 bits (429), Expect = 2e-41
 Identities = 299/1449 (20%), Positives = 554/1449 (38%), Gaps = 137/1449 (9%)

Query: 668  IKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSES 727
            ++ L+ G +Y  ++IS+ +                       TV  +T P  P      S
Sbjct: 300  LQDLQAGTIYNFRIISLDE---------------------ERTVVLQTDPLPP-ARFGVS 337

Query: 728  VTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTAT--SVNIPDLLPGRK 785
              + T++S  V W  +S  V+ + V+    E   + Q + +  + +       +L  G K
Sbjct: 338  KEKTTSTSLHVWWTPSSGKVTSYEVQL-FDENNQKIQGVQIQESTSWNEYTFFNLTAGSK 396

Query: 786  YIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVY 845
            Y + +  +S  G++S  + T+ +T P    D  +      S+++ WS     +  YR++ 
Sbjct: 397  YNIAITAVS-GGKRSFSVYTNGSTVPSPVKDIGIS-TKANSLLISWSHGSGNVERYRLML 454

Query: 846  SPS---VEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTP 902
                  V G   + +    A S     L PG  YN+T+       ++    + +      
Sbjct: 455  MDKGILVHGGVVDKH----ATSYAFHGLTPGYLYNLTVMTEAAGLQNYRWKLVRT----- 505

Query: 903  RSDTVPSPRDLQFVEVTD----VKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLP-IS 957
                  +P ++  ++VT+      + + W  P   V  Y + +       E     P I+
Sbjct: 506  ------APMEVSNLKVTNDGSLTSLKVKWQRPPGNVDSYNITLSHKGTIKESRVLAPWIT 559

Query: 958  RNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDS-TVLVR 1016
               F E   L PG  Y   V  VS G  S    A   T  D   NL+  N     +++V 
Sbjct: 560  ETHFKE---LVPGRLYQVTVSCVS-GELSAQKMAVGRTFPDKVANLEANNNGRMRSLVVS 615

Query: 1017 WTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRN--LQPASEYTVSLVAIKGNQE 1074
            W+PP      YR+ +            VG   ++Y + +  L P  +Y V ++   GN +
Sbjct: 616  WSPPAGDWEQYRILL-FNDSVVLLNITVGKEETQYVMDDTGLVPGRQYEVEVIVESGNLK 674

Query: 1075 SPKATGVFTTLQPGSSIPPYNTEVTETTIVITW-TP-APRIGFKLGVRPSQGGEAPREVT 1132
            + +     T   P + +        ET++ I W TP A    + + +         + ++
Sbjct: 675  NSERCQGRTV--PLAVLQLRVKHANETSLSIMWQTPVAEWEKYIISLADRDLLLIHKSLS 732

Query: 1133 SDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLT 1192
             D+     + L PG +Y+ T+  +    +  + +  + V   +  T+LH+     T  L 
Sbjct: 733  KDAKEFTFTDLVPGRKYMATVTSISGDLKNSSSVKGRTVP--AQVTDLHVANQGMTSSLF 790

Query: 1193 VSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKD 1252
             +W ++   D+  Y++     N    N   E + ++ S  +F +L  G  Y+V V TV  
Sbjct: 791  TNWTQAQG-DVEFYQVLLIHENVVIKN---ESISSETSRYSFHSLKSGSLYSVVVTTVSG 846

Query: 1253 DKES--VPISDTIIPEVPQLTDLSFVDITDSS----IGLRWTPLNSSTIIGYRITVVAAG 1306
               S  V +    +P     + +S V + +S     + + W  L    +  Y +T+   G
Sbjct: 847  GISSRQVVVEGRTVP-----SSVSGVTVNNSGRNDYLSVSWL-LAPGDVDNYEVTLSHDG 900

Query: 1307 EGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAVPPPTD-LR 1365
            + +      +  SV   + + L PG  Y +++ T    G+    + +Q+  VP     + 
Sbjct: 901  KVVQSL--VIAKSVRECSFSSLTPGRLYTVTITT--RSGKYENHSFSQERTVPDKVQGVS 956

Query: 1366 FTNIG-PDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAEL-SISPSDNAVVLTNLLPGT 1423
             +N    D +RV+W      D  ++ V    +KN+ +  +  SI  S+N  V   L+PG 
Sbjct: 957  VSNSARSDYLRVSWVHATG-DFDHYEVT---IKNKNNFIQTKSIPKSENECVFVQLVPGR 1012

Query: 1424 EYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRH 1483
             Y V+V++   Q+E+   +G  +T  +    +   + +     V W      +  Y I+ 
Sbjct: 1013 LYSVTVTTKSGQYEANE-QGNGRTIPEPVKDLTLRNRSTEDLHVTWSGANGDVDQYEIQL 1071

Query: 1484 HPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPR 1543
                    P    V ++      T+LTPG +Y + ++ ++G  +    I +  TV    +
Sbjct: 1072 LFNDMKVFPPFHLV-NTATEYRFTSLTPGRQYKILVLTISGDVQQSAFI-EGFTVPSAVK 1129

Query: 1544 DLEVVAATPT-SLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPG 1602
            ++ +     T SL ++W      V  Y  T      +  V   T+P      T   L+ G
Sbjct: 1130 NIHISPNGATDSLTVNWTPGGGDVDSY--TVSAFRHSQKVDSQTIPKHVFEHTFHRLEAG 1187

Query: 1603 VDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSIS-----VKWLPSS 1657
              Y I + +V+G     +    I++  RT    P+ +Q   + DN+ S     V W  ++
Sbjct: 1188 EQYQIMIASVSG-----SLKNQINVVGRTV---PASVQGV-IADNAYSSYSLIVSWQKAA 1238

Query: 1658 SPVTGYRVTTTPKNGPGPTKTKTAGPDQTEM-TIEGLQPTVEYVVSVYAQNP---SGESQ 1713
                 Y +    +NG       T+ P  T+    E L P  +Y + +   +    S E+Q
Sbjct: 1239 GVAERYDILLLTENGI--LLRNTSEPATTKQHKFEDLTPGKKYKIQILTVSGGLFSKEAQ 1296

Query: 1714 P---LVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPA 1770
                 V  AVT+      L  T+     +   W + +G++S Y +   +P+  + E    
Sbjct: 1297 TEGRTVPAAVTD------LRITENSTRHLSFRWTASEGELSWYNIFLYNPDGNLQERAQV 1350

Query: 1771 PDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLS 1830
             D    +   Q L  G  Y + +V    ++ ++  I  ++            + T  SL 
Sbjct: 1351 -DPLVQSFSFQNLLQGRMYKMVIVTHSGELSNESFIFGRTVPASVSHLRGSNRNTTDSLW 1409

Query: 1831 AQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTL 1890
              W+P +     Y + +      G  KE     D +     GL+   KY + V      L
Sbjct: 1410 FNWSPASGDFDFYELILY--NPNGTKKENWKDKDLTEWRFQGLVPGRKYVLWVVTHSGDL 1467

Query: 1891 TSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTE--TITGFQVDAVPANGQTPI 1948
            +++      T     SPP      D   T++ I+W+   +      F++  +P +  T  
Sbjct: 1468 SNKVTAESRTA---PSPPSLMSFADIANTSLAITWKGPPDWTDYNDFELQWLPRDALTVF 1524

Query: 1949 QRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNA---RSSPVVIDASTAIDAPSNLRFLAT 2005
                        + GL+PG  Y+  + T++ ++    S P+     T  D   NL     
Sbjct: 1525 NPYNNRKSEGRIVYGLRPGRSYQFNVKTVSGDSWKTYSKPIFGSVRTKPDKIQNLHCRPQ 1584

Query: 2006 TPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVI 2065
               ++  SW PP +   GY I+  K  +   E   +     +   I  L P   Y + + 
Sbjct: 1585 NSTAIACSWIPPDSDFDGYSIECRKMDTQEVEFSRKLEKEKSLLNIMMLVPHKRYLVSIK 1644

Query: 2066 ALKNNQKSE 2074
                   SE
Sbjct: 1645 VQSAGMTSE 1653



 Score =  164 bits (416), Expect = 7e-40
 Identities = 288/1338 (21%), Positives = 506/1338 (37%), Gaps = 116/1338 (8%)

Query: 662  HLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPL 721
            H  SY   GL PG +Y   L  + +    +  R+    T                  +P+
Sbjct: 469  HATSYAFHGLTPGYLY--NLTVMTEAAGLQNYRWKLVRT------------------APM 508

Query: 722  VATSESVT-EITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL 780
              ++  VT + + +S  V W      V  + +   LS +G   +   L    T  +  +L
Sbjct: 509  EVSNLKVTNDGSLTSLKVKWQRPPGNVDSYNI--TLSHKGTIKESRVLAPWITETHFKEL 566

Query: 781  LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDD-TSIVVRWSRPQAPIT 839
            +PGR Y V V  +S  GE S        T PD   +   +      S+VV WS P     
Sbjct: 567  VPGRLYQVTVSCVS--GELSAQKMAVGRTFPDKVANLEANNNGRMRSLVVSWSPPAGDWE 624

Query: 840  GYRI-VYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQET 898
             YRI +++ SV   +  +   ET   +  + L PG QY + +     N +++        
Sbjct: 625  QYRILLFNDSVVLLNITVGKEETQYVMDDTGLVPGRQYEVEVIVESGNLKNSE------- 677

Query: 899  TGTPRSDTVP-SPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPIS 957
                +  TVP +   L+     +  ++IMW  P +    Y + +   +L   H + L   
Sbjct: 678  --RCQGRTVPLAVLQLRVKHANETSLSIMWQTPVAEWEKYIISLADRDLLLIH-KSLSKD 734

Query: 958  RNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNE-TDSTVLVR 1016
               F   T L PG  Y   V ++S   ++      +T      T+L   N+   S++   
Sbjct: 735  AKEFT-FTDLVPGRKYMATVTSISGDLKNSSSVKGRTVPAQV-TDLHVANQGMTSSLFTN 792

Query: 1017 WTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESP 1076
            WT  +  +  Y++ + +      +  ++    S+Y   +L+  S Y+V +  + G   S 
Sbjct: 793  WTQAQGDVEFYQVLL-IHENVVIKNESISSETSRYSFHSLKSGSLYSVVVTTVSGGISSR 851

Query: 1077 KATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPRE--VTSD 1134
            +      T+    S    N       + ++W  AP       V  S  G+  +   +   
Sbjct: 852  QVVVEGRTVPSSVSGVTVNNSGRNDYLSVSWLLAPGDVDNYEVTLSHDGKVVQSLVIAKS 911

Query: 1135 SGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVS 1194
                  S LTPG  Y  TI       E  +    + V       ++   A  D   L VS
Sbjct: 912  VRECSFSSLTPGRLYTVTITTRSGKYENHSFSQERTVPDKVQGVSVSNSARSD--YLRVS 969

Query: 1195 WERSTTPDITGYRITTTPTNGQQGNSLE-EVVHADQSSCTFDNLSPGLEYNVSVYTVKDD 1253
            W  + T D   Y +T    N    N ++ + +   ++ C F  L PG  Y+V+V T    
Sbjct: 970  WVHA-TGDFDHYEVTIKNKN----NFIQTKSIPKSENECVFVQLVPGRLYSVTVTTKSGQ 1024

Query: 1254 KESVPISD-TIIPEVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIF 1312
             E+    +   IPE   + DL+  + +   + + W+  N   +  Y I ++     + +F
Sbjct: 1025 YEANEQGNGRTIPE--PVKDLTLRNRSTEDLHVTWSGANGD-VDQYEIQLLF--NDMKVF 1079

Query: 1313 EDF-VDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAVPPPTDLRFTNIGP 1371
              F + ++   Y  T L PG  Y I V+T+   G+   +   +   V  P+ ++  +I P
Sbjct: 1080 PPFHLVNTATEYRFTSLTPGRQYKILVLTI--SGDVQQSAFIEGFTV--PSAVKNIHISP 1135

Query: 1372 ----DTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVV 1427
                D++ V W P    D+ ++ V  S  ++ + V   +I           L  G +Y +
Sbjct: 1136 NGATDSLTVNWTPGGG-DVDSYTV--SAFRHSQKVDSQTIPKHVFEHTFHRLEAGEQYQI 1192

Query: 1428 SVSSVYEQHESTPLRGR-QKTGLDSPTGID--FSDITANSFT--VHWIAPRATITGYRIR 1482
             ++SV     S  L+ +    G   P  +    +D   +S++  V W         Y I 
Sbjct: 1193 MIASV-----SGSLKNQINVVGRTVPASVQGVIADNAYSSYSLIVSWQKAAGVAERYDIL 1247

Query: 1483 HHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVP 1542
               E+     R    P +       +LTPG +Y + I+ ++G   S     +  TV    
Sbjct: 1248 LLTEN-GILLRNTSEPATTKQHKFEDLTPGKKYKIQILTVSGGLFSKEAQTEGRTVPAAV 1306

Query: 1543 RDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPG 1602
             DL +   +   L   W A    + +Y I      GN   +    P  +S  +   L  G
Sbjct: 1307 TDLRITENSTRHLSFRWTASEGELSWYNIFLYNPDGNLQERAQVDPLVQS-FSFQNLLQG 1365

Query: 1603 VDYTITVYAVTGRGDSPA----SSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSS 1658
              Y + +   +G   + +     + P S+++     + S    TD    S+   W P+S 
Sbjct: 1366 RMYKMVIVTHSGELSNESFIFGRTVPASVSHL----RGSNRNTTD----SLWFNWSPASG 1417

Query: 1659 PVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE-SQPLVQ 1717
                Y +     N  G  K      D TE   +GL P  +YV+ V     SG+ S  +  
Sbjct: 1418 DFDFYELILYNPN--GTKKENWKDKDLTEWRFQGLVPGRKYVLWVVTH--SGDLSNKVTA 1473

Query: 1718 TAVTNIDRPKGLAFTDVDVDSIKIAWESPQG--QVSRYRVTYSSPEDGIHELFPAPDGEE 1775
             + T    P  ++F D+   S+ I W+ P      + + + +  P D +    P  + + 
Sbjct: 1474 ESRTAPSPPSLMSFADIANTSLAITWKGPPDWTDYNDFELQW-LPRDALTVFNPYNNRKS 1532

Query: 1776 DTAELQGLRPGSEYTVSVVALHDD---MESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQ 1832
            +   + GLRPG  Y  +V  +  D     S+P+ G+  T      +L       T+++  
Sbjct: 1533 EGRIVYGLRPGRSYQFNVKTVSGDSWKTYSKPIFGSVRTKPDKIQNLHCRPQNSTAIACS 1592

Query: 1833 WTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTS 1892
            W PP+    GY +     +         L  + S + +  L+   +Y VS+      +TS
Sbjct: 1593 WIPPDSDFDGYSIECRKMDTQEVEFSRKLEKEKSLLNIMMLVPHKRYLVSIKVQSAGMTS 1652

Query: 1893 RPAQGVVTTL--ENVSPPRRARVTD--------ATETTITISWRTKTE-TITGFQVDAVP 1941
               +    T+      PP   RV +        +   T+  SW + T   +  F V    
Sbjct: 1653 EVVEDSTITMIDRPPPPPPHIRVNEKDVLISKSSINFTVNCSWFSDTNGAVKYFTVVVRE 1712

Query: 1942 ANGQTPIQRTIKPDVRSY 1959
            A+G   ++   +  + SY
Sbjct: 1713 ADGSDELKPEQQHPLPSY 1730



 Score =  145 bits (365), Expect = 6e-34
 Identities = 235/1152 (20%), Positives = 447/1152 (38%), Gaps = 110/1152 (9%)

Query: 967  LSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITG 1026
            L  G  Y F++ ++    E + +  Q      A   +     T +++ V WTP   ++T 
Sbjct: 303  LQAGTIYNFRIISLD---EERTVVLQTDPLPPARFGVSKEKTTSTSLHVWWTPSSGKVTS 359

Query: 1027 YRLTV--GLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTT 1084
            Y + +     ++ Q  Q     S ++Y   NL   S+Y +++ A+ G + S      F+ 
Sbjct: 360  YEVQLFDENNQKIQGVQIQESTSWNEYTFFNLTAGSKYNIAITAVSGGKRS------FSV 413

Query: 1085 LQPGSSIPPYNTEVTETT----IVITWTPAPRI--GFKLGVRPS----QGGEAPREVTSD 1134
               GS++P    ++  +T    ++I+W+        ++L +        GG   +  TS 
Sbjct: 414  YTNGSTVPSPVKDIGISTKANSLLISWSHGSGNVERYRLMLMDKGILVHGGVVDKHATS- 472

Query: 1135 SGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVS 1194
                   GLTPG  Y+Y + V+ +           V T     +NL +  +     L V 
Sbjct: 473  ---YAFHGLTPG--YLYNLTVMTEAAGLQNYRWKLVRTAPMEVSNLKVTNDGSLTSLKVK 527

Query: 1195 WERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCT-FDNLSPGLEYNVSVYTVKDD 1253
            W+R    ++  Y IT +     +G   E  V A   + T F  L PG  Y V+V  V  +
Sbjct: 528  WQRPPG-NVDSYNITLS----HKGTIKESRVLAPWITETHFKELVPGRLYQVTVSCVSGE 582

Query: 1254 --KESVPISDTIIPEVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGEGIPI 1311
               + + +  T   +V  L   +   +   S+ + W+P  +     YRI +    + + +
Sbjct: 583  LSAQKMAVGRTFPDKVANLEANNNGRMR--SLVVSWSP-PAGDWEQYRILLF--NDSVVL 637

Query: 1312 FEDFVDSSVGYYTV--TGLEPGIDYDISVITLINGGESAPTTLTQQTAVPPPT-DLRFTN 1368
                V      Y +  TGL PG  Y++ VI  +  G    +   Q   VP     LR  +
Sbjct: 638  LNITVGKEETQYVMDDTGLVPGRQYEVEVI--VESGNLKNSERCQGRTVPLAVLQLRVKH 695

Query: 1369 IGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVS 1428
                ++ + W  P + +   +++  S    +  +   S+S        T+L+PG +Y+ +
Sbjct: 696  ANETSLSIMWQTPVA-EWEKYII--SLADRDLLLIHKSLSKDAKEFTFTDLVPGRKYMAT 752

Query: 1429 VSSVY-EQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEH 1487
            V+S+  +   S+ ++GR      +   +    +T++ FT +W   +  +  Y++    E+
Sbjct: 753  VTSISGDLKNSSSVKGRTVPAQVTDLHVANQGMTSSLFT-NWTQAQGDVEFYQVLLIHEN 811

Query: 1488 FSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEV 1547
                 + + +    +  +  +L  G+ Y V +  ++G   S  ++ +  TV      + V
Sbjct: 812  VV--IKNESISSETSRYSFHSLKSGSLYSVVVTTVSGGISSRQVVVEGRTVPSSVSGVTV 869

Query: 1548 VAATPTSLL-ISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYT 1606
              +     L +SW      V  Y +T    G    VQ   +  S    + S L PG  YT
Sbjct: 870  NNSGRNDYLSVSWLLAPGDVDNYEVTLSHDG--KVVQSLVIAKSVRECSFSSLTPGRLYT 927

Query: 1607 ITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTD-VQDNSISVKWLPSSSPVTGYRV 1665
            +T+   +G+ ++ + S+      RT  DK   + V++  + + + V W+ ++     Y V
Sbjct: 928  VTITTRSGKYENHSFSQE-----RTVPDKVQGVSVSNSARSDYLRVSWVHATGDFDHYEV 982

Query: 1666 TTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDR 1725
            T   KN     +TK+    + E     L P   Y V+V  +  SG+ +   Q     I  
Sbjct: 983  TIKNKNNF--IQTKSIPKSENECVFVQLVPGRLYSVTVTTK--SGQYEANEQGNGRTIPE 1038

Query: 1726 P-KGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTA---ELQ 1781
            P K L   +   + + + W    G V +Y +     +    ++FP P    +TA      
Sbjct: 1039 PVKDLTLRNRSTEDLHVTWSGANGDVDQYEIQLLFND---MKVFP-PFHLVNTATEYRFT 1094

Query: 1782 GLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPT----SLSAQWTPPN 1837
             L PG +Y + V+ +  D++    I         P+ +K   ++P     SL+  WTP  
Sbjct: 1095 SLTPGRQYKILVLTISGDVQQSAFI----EGFTVPSAVKNIHISPNGATDSLTVNWTPGG 1150

Query: 1838 VQLTGYRV-----------RVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYAL 1886
              +  Y V           +  PK           A +   ++++ +  + K +++V   
Sbjct: 1151 GDVDSYTVSAFRHSQKVDSQTIPKHVFEHTFHRLEAGEQYQIMIASVSGSLKNQINVVG- 1209

Query: 1887 KDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQT 1946
                     QGV+                 +  ++ +SW+        + +  +  NG  
Sbjct: 1210 --RTVPASVQGVIAD------------NAYSSYSLIVSWQKAAGVAERYDILLLTENGIL 1255

Query: 1947 PIQRTIKP-DVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLAT 2005
             ++ T +P   + +    L PG  YKI + T++    S     +  T   A ++LR    
Sbjct: 1256 -LRNTSEPATTKQHKFEDLTPGKKYKIQILTVSGGLFSKEAQTEGRTVPAAVTDLRITEN 1314

Query: 2006 TPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVI 2065
            +   L   W      ++ Y I    P    +E   +  P V   +   L  G  Y + ++
Sbjct: 1315 STRHLSFRWTASEGELSWYNIFLYNPDGNLQERA-QVDPLVQSFSFQNLLQGRMYKMVIV 1373

Query: 2066 ALKNNQKSEPLI 2077
                   +E  I
Sbjct: 1374 THSGELSNESFI 1385



 Score = 35.4 bits (80), Expect = 0.69
 Identities = 37/194 (19%), Positives = 76/194 (39%), Gaps = 25/194 (12%)

Query: 628  IQWNAPQP-SHISKYILRWRPKNSV---GRWKEATIPGHLNSYTIKGLKPGVVYEGQLIS 683
            I W  P   +  + + L+W P++++     +      G +    + GL+PG  Y+  + +
Sbjct: 1497 ITWKGPPDWTDYNDFELQWLPRDALTVFNPYNNRKSEGRI----VYGLRPGRSYQFNVKT 1552

Query: 684  IQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSA 743
            +     +  ++  F +  T      N           L    ++ T I  S     W+  
Sbjct: 1553 VSGDSWKTYSKPIFGSVRTKPDKIQN-----------LHCRPQNSTAIACS-----WIPP 1596

Query: 744  SDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLIL 803
                 G+ +E    +  +      L    + +NI  L+P ++Y+V++ ++   G  S ++
Sbjct: 1597 DSDFDGYSIECRKMDTQEVEFSRKLEKEKSLLNIMMLVPHKRYLVSI-KVQSAGMTSEVV 1655

Query: 804  STSQTTAPDAPPDP 817
              S  T  D PP P
Sbjct: 1656 EDSTITMIDRPPPP 1669


>gi|157952213 protein tyrosine phosphatase, receptor type, B isoform b
            precursor [Homo sapiens]
          Length = 1997

 Score =  187 bits (476), Expect = 8e-47
 Identities = 273/1275 (21%), Positives = 508/1275 (39%), Gaps = 88/1275 (6%)

Query: 768  LPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSI 827
            + +T    N+ DL  G  Y  N   IS D E++++L T     P A    + ++   TS+
Sbjct: 73   IDNTTYGCNLQDLQAGTIY--NFRIISLDEERTVVLQTDPL--PPARFGVSKEKTTSTSL 128

Query: 828  VVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETA--NSVTLSDLQPGVQYNITIYAVEE 885
             V W+     +T Y +            + + E+   N  T  +L  G +YNI I AV  
Sbjct: 129  HVWWTPSSGKVTSYEVQLFDENNQKIQGVQIQESTSWNEYTFFNLTAGSKYNIAITAVSG 188

Query: 886  NQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVN 945
             + S  V     T G+    TVPSP     +      + I W+     V  YR+ ++   
Sbjct: 189  GKRSFSVY----TNGS----TVPSPVKDIGISTKANSLLISWSHGSGNVERYRLMLMDKG 240

Query: 946  LPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQF 1005
            +   HG  +     ++A   GL+PG  Y   V   + G ++      +T  ++  +NL+ 
Sbjct: 241  IL-VHGGVVDKHATSYA-FHGLTPGYLYNLTVMTEAAGLQNYRWKLVRTAPMEV-SNLKV 297

Query: 1006 VNETDSTVL-VRWTPPRAQITGYRLTVGLTRRGQPRQYNV-GPSVSKYPLRNLQPASEYT 1063
             N+   T L V+W  P   +  Y +T  L+ +G  ++  V  P +++   + L P   Y 
Sbjct: 298  TNDGSLTSLKVKWQRPPGNVDSYNIT--LSHKGTIKESRVLAPWITETHFKELVPGRLYQ 355

Query: 1064 VSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGV---- 1119
            V++  + G   + K   V  T     +    N      ++V++W+P      +  +    
Sbjct: 356  VTVSCVSGELSAQKMA-VGRTFPDKVANLEANNNGRMRSLVVSWSPPAGDWEQYRILLFN 414

Query: 1120 ------RPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTP 1173
                    + G E  + V  D+G      L PG +Y   + ++  G  +++        P
Sbjct: 415  DSVVLLNITVGKEETQYVMDDTG------LVPGRQYEVEV-IVESGNLKNSERCQGRTVP 467

Query: 1174 LSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCT 1233
            L+        AN  +  L++ W+   TP +  +         +    + + +  D    T
Sbjct: 468  LAVLQLRVKHANETS--LSIMWQ---TP-VAEWEKYIISLADRDLLLIHKSLSKDAKEFT 521

Query: 1234 FDNLSPGLEYNVSVYTVKDD-KESVPISDTIIPEVPQLTDLSFVDI-TDSSIGLRWTPLN 1291
            F +L PG +Y  +V ++  D K S  +    +P   Q+TDL   +    SS+   WT   
Sbjct: 522  FTDLVPGRKYMATVTSISGDLKNSSSVKGRTVPA--QVTDLHVANQGMTSSLFTNWTQAQ 579

Query: 1292 SSTIIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTT 1351
                  Y++ ++   E + I  + + S    Y+   L+ G  Y + V+T ++GG S+   
Sbjct: 580  GDVEF-YQVLLIH--ENVVIKNESISSETSRYSFHSLKSGSLYSV-VVTTVSGGISSRQV 635

Query: 1352 LTQQTAVPPPTD-LRFTNIGP-DTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISP 1409
            + +   VP     +   N G  D + V+W   P  D+ N+ V  S   + + V  L I+ 
Sbjct: 636  VVEGRTVPSSVSGVTVNNSGRNDYLSVSWLLAPG-DVDNYEVTLS--HDGKVVQSLVIAK 692

Query: 1410 SDNAVVLTNLLPGTEYVVSV---SSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFT 1466
            S      ++L PG  Y V++   S  YE H  +    +++T  D   G+  S+   + + 
Sbjct: 693  SVRECSFSSLTPGRLYTVTITTRSGKYENHSFS----QERTVPDKVQGVSVSNSARSDYL 748

Query: 1467 -VHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGR 1525
             V W+        Y +    ++   + +   +P S N      L PG  Y V++   +G+
Sbjct: 749  RVSWVHATGDFDHYEVTIKNKNNFIQTKS--IPKSENECVFVQLVPGRLYSVTVTTKSGQ 806

Query: 1526 EESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRIT--YGETGGNSPVQ 1583
             E+    G   T+ +  +DL +   +   L ++W      V  Y I   + +     P  
Sbjct: 807  YEANEQ-GNGRTIPEPVKDLTLRNRSTEDLHVTWSGANGDVDQYEIQLLFNDMKVFPP-- 863

Query: 1584 EFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTD 1643
             F +  + +    + L PG  Y I V  ++G     A  +  ++    +    S    TD
Sbjct: 864  -FHLVNTATEYRFTSLTPGRQYKILVLTISGDVQQSAFIEGFTVPSAVKNIHISPNGATD 922

Query: 1644 VQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSV 1703
                S++V W P    V  Y V+    +      ++T      E T   L+   +Y + +
Sbjct: 923  ----SLTVNWTPGGGDVDSYTVSAFRHSQK--VDSQTIPKHVFEHTFHRLEAGEQYQIMI 976

Query: 1704 YAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDG 1763
             + + S ++Q  V            +A       S+ ++W+   G   RY +   + E+G
Sbjct: 977  ASVSGSLKNQINVVGRTVPASVQGVIADNAYSSYSLIVSWQKAAGVAERYDILLLT-ENG 1035

Query: 1764 IHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQ 1823
            I     +        + + L PG +Y + ++ +   + S+       T   A TDL+ T+
Sbjct: 1036 ILLRNTSEPATTKQHKFEDLTPGKKYKIQILTVSGGLFSKEAQTEGRTVPAAVTDLRITE 1095

Query: 1824 VTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKE-INLAPDSSSVVVSGLMVATKYEVS 1882
             +   LS +WT    +L+ Y + +   +  G ++E   + P   S     L+    Y++ 
Sbjct: 1096 NSTRHLSFRWTASEGELSWYNIFLYNPD--GNLQERAQVDPLVQSFSFQNLLQGRMYKMV 1153

Query: 1883 VYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPA 1942
            +      L++       T   +VS  R +     T  ++  +W   +     +++     
Sbjct: 1154 IVTHSGELSNESFIFGRTVPASVSHLRGSNRN--TTDSLWFNWSPASGDFDFYELILYNP 1211

Query: 1943 NGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRF 2002
            NG T  +     D+  +   GL PG  Y +++ T +    S+ V  ++ TA   PS + F
Sbjct: 1212 NG-TKKENWKDKDLTEWRFQGLVPGRKYVLWVVT-HSGDLSNKVTAESRTAPSPPSLMSF 1269

Query: 2003 LATTPNSLLVSWQPP 2017
                  SL ++W+ P
Sbjct: 1270 ADIANTSLAITWKGP 1284



 Score =  169 bits (429), Expect = 2e-41
 Identities = 299/1449 (20%), Positives = 554/1449 (38%), Gaps = 137/1449 (9%)

Query: 668  IKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSES 727
            ++ L+ G +Y  ++IS+ +                       TV  +T P  P      S
Sbjct: 82   LQDLQAGTIYNFRIISLDE---------------------ERTVVLQTDPLPP-ARFGVS 119

Query: 728  VTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTAT--SVNIPDLLPGRK 785
              + T++S  V W  +S  V+ + V+    E   + Q + +  + +       +L  G K
Sbjct: 120  KEKTTSTSLHVWWTPSSGKVTSYEVQL-FDENNQKIQGVQIQESTSWNEYTFFNLTAGSK 178

Query: 786  YIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVY 845
            Y + +  +S  G++S  + T+ +T P    D  +      S+++ WS     +  YR++ 
Sbjct: 179  YNIAITAVS-GGKRSFSVYTNGSTVPSPVKDIGIS-TKANSLLISWSHGSGNVERYRLML 236

Query: 846  SPS---VEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTP 902
                  V G   + +    A S     L PG  YN+T+       ++    + +      
Sbjct: 237  MDKGILVHGGVVDKH----ATSYAFHGLTPGYLYNLTVMTEAAGLQNYRWKLVRT----- 287

Query: 903  RSDTVPSPRDLQFVEVTD----VKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLP-IS 957
                  +P ++  ++VT+      + + W  P   V  Y + +       E     P I+
Sbjct: 288  ------APMEVSNLKVTNDGSLTSLKVKWQRPPGNVDSYNITLSHKGTIKESRVLAPWIT 341

Query: 958  RNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDS-TVLVR 1016
               F E   L PG  Y   V  VS G  S    A   T  D   NL+  N     +++V 
Sbjct: 342  ETHFKE---LVPGRLYQVTVSCVS-GELSAQKMAVGRTFPDKVANLEANNNGRMRSLVVS 397

Query: 1017 WTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRN--LQPASEYTVSLVAIKGNQE 1074
            W+PP      YR+ +            VG   ++Y + +  L P  +Y V ++   GN +
Sbjct: 398  WSPPAGDWEQYRILL-FNDSVVLLNITVGKEETQYVMDDTGLVPGRQYEVEVIVESGNLK 456

Query: 1075 SPKATGVFTTLQPGSSIPPYNTEVTETTIVITW-TP-APRIGFKLGVRPSQGGEAPREVT 1132
            + +     T   P + +        ET++ I W TP A    + + +         + ++
Sbjct: 457  NSERCQGRTV--PLAVLQLRVKHANETSLSIMWQTPVAEWEKYIISLADRDLLLIHKSLS 514

Query: 1133 SDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLT 1192
             D+     + L PG +Y+ T+  +    +  + +  + V   +  T+LH+     T  L 
Sbjct: 515  KDAKEFTFTDLVPGRKYMATVTSISGDLKNSSSVKGRTVP--AQVTDLHVANQGMTSSLF 572

Query: 1193 VSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKD 1252
             +W ++   D+  Y++     N    N   E + ++ S  +F +L  G  Y+V V TV  
Sbjct: 573  TNWTQAQG-DVEFYQVLLIHENVVIKN---ESISSETSRYSFHSLKSGSLYSVVVTTVSG 628

Query: 1253 DKES--VPISDTIIPEVPQLTDLSFVDITDSS----IGLRWTPLNSSTIIGYRITVVAAG 1306
               S  V +    +P     + +S V + +S     + + W  L    +  Y +T+   G
Sbjct: 629  GISSRQVVVEGRTVP-----SSVSGVTVNNSGRNDYLSVSWL-LAPGDVDNYEVTLSHDG 682

Query: 1307 EGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAVPPPTD-LR 1365
            + +      +  SV   + + L PG  Y +++ T    G+    + +Q+  VP     + 
Sbjct: 683  KVVQSL--VIAKSVRECSFSSLTPGRLYTVTITT--RSGKYENHSFSQERTVPDKVQGVS 738

Query: 1366 FTNIG-PDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAEL-SISPSDNAVVLTNLLPGT 1423
             +N    D +RV+W      D  ++ V    +KN+ +  +  SI  S+N  V   L+PG 
Sbjct: 739  VSNSARSDYLRVSWVHATG-DFDHYEVT---IKNKNNFIQTKSIPKSENECVFVQLVPGR 794

Query: 1424 EYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRH 1483
             Y V+V++   Q+E+   +G  +T  +    +   + +     V W      +  Y I+ 
Sbjct: 795  LYSVTVTTKSGQYEANE-QGNGRTIPEPVKDLTLRNRSTEDLHVTWSGANGDVDQYEIQL 853

Query: 1484 HPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPR 1543
                    P    V ++      T+LTPG +Y + ++ ++G  +    I +  TV    +
Sbjct: 854  LFNDMKVFPPFHLV-NTATEYRFTSLTPGRQYKILVLTISGDVQQSAFI-EGFTVPSAVK 911

Query: 1544 DLEVVAATPT-SLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPG 1602
            ++ +     T SL ++W      V  Y  T      +  V   T+P      T   L+ G
Sbjct: 912  NIHISPNGATDSLTVNWTPGGGDVDSY--TVSAFRHSQKVDSQTIPKHVFEHTFHRLEAG 969

Query: 1603 VDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSIS-----VKWLPSS 1657
              Y I + +V+G     +    I++  RT    P+ +Q   + DN+ S     V W  ++
Sbjct: 970  EQYQIMIASVSG-----SLKNQINVVGRTV---PASVQGV-IADNAYSSYSLIVSWQKAA 1020

Query: 1658 SPVTGYRVTTTPKNGPGPTKTKTAGPDQTEM-TIEGLQPTVEYVVSVYAQNP---SGESQ 1713
                 Y +    +NG       T+ P  T+    E L P  +Y + +   +    S E+Q
Sbjct: 1021 GVAERYDILLLTENGI--LLRNTSEPATTKQHKFEDLTPGKKYKIQILTVSGGLFSKEAQ 1078

Query: 1714 P---LVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPA 1770
                 V  AVT+      L  T+     +   W + +G++S Y +   +P+  + E    
Sbjct: 1079 TEGRTVPAAVTD------LRITENSTRHLSFRWTASEGELSWYNIFLYNPDGNLQERAQV 1132

Query: 1771 PDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLS 1830
             D    +   Q L  G  Y + +V    ++ ++  I  ++            + T  SL 
Sbjct: 1133 -DPLVQSFSFQNLLQGRMYKMVIVTHSGELSNESFIFGRTVPASVSHLRGSNRNTTDSLW 1191

Query: 1831 AQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTL 1890
              W+P +     Y + +      G  KE     D +     GL+   KY + V      L
Sbjct: 1192 FNWSPASGDFDFYELILY--NPNGTKKENWKDKDLTEWRFQGLVPGRKYVLWVVTHSGDL 1249

Query: 1891 TSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTE--TITGFQVDAVPANGQTPI 1948
            +++      T     SPP      D   T++ I+W+   +      F++  +P +  T  
Sbjct: 1250 SNKVTAESRTA---PSPPSLMSFADIANTSLAITWKGPPDWTDYNDFELQWLPRDALTVF 1306

Query: 1949 QRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNA---RSSPVVIDASTAIDAPSNLRFLAT 2005
                        + GL+PG  Y+  + T++ ++    S P+     T  D   NL     
Sbjct: 1307 NPYNNRKSEGRIVYGLRPGRSYQFNVKTVSGDSWKTYSKPIFGSVRTKPDKIQNLHCRPQ 1366

Query: 2006 TPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVI 2065
               ++  SW PP +   GY I+  K  +   E   +     +   I  L P   Y + + 
Sbjct: 1367 NSTAIACSWIPPDSDFDGYSIECRKMDTQEVEFSRKLEKEKSLLNIMMLVPHKRYLVSIK 1426

Query: 2066 ALKNNQKSE 2074
                   SE
Sbjct: 1427 VQSAGMTSE 1435



 Score =  164 bits (416), Expect = 7e-40
 Identities = 288/1338 (21%), Positives = 506/1338 (37%), Gaps = 116/1338 (8%)

Query: 662  HLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPL 721
            H  SY   GL PG +Y   L  + +    +  R+    T                  +P+
Sbjct: 251  HATSYAFHGLTPGYLY--NLTVMTEAAGLQNYRWKLVRT------------------APM 290

Query: 722  VATSESVT-EITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDL 780
              ++  VT + + +S  V W      V  + +   LS +G   +   L    T  +  +L
Sbjct: 291  EVSNLKVTNDGSLTSLKVKWQRPPGNVDSYNI--TLSHKGTIKESRVLAPWITETHFKEL 348

Query: 781  LPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDD-TSIVVRWSRPQAPIT 839
            +PGR Y V V  +S  GE S        T PD   +   +      S+VV WS P     
Sbjct: 349  VPGRLYQVTVSCVS--GELSAQKMAVGRTFPDKVANLEANNNGRMRSLVVSWSPPAGDWE 406

Query: 840  GYRI-VYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQET 898
             YRI +++ SV   +  +   ET   +  + L PG QY + +     N +++        
Sbjct: 407  QYRILLFNDSVVLLNITVGKEETQYVMDDTGLVPGRQYEVEVIVESGNLKNSE------- 459

Query: 899  TGTPRSDTVP-SPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPIS 957
                +  TVP +   L+     +  ++IMW  P +    Y + +   +L   H + L   
Sbjct: 460  --RCQGRTVPLAVLQLRVKHANETSLSIMWQTPVAEWEKYIISLADRDLLLIH-KSLSKD 516

Query: 958  RNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNE-TDSTVLVR 1016
               F   T L PG  Y   V ++S   ++      +T      T+L   N+   S++   
Sbjct: 517  AKEFT-FTDLVPGRKYMATVTSISGDLKNSSSVKGRTVPAQV-TDLHVANQGMTSSLFTN 574

Query: 1017 WTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESP 1076
            WT  +  +  Y++ + +      +  ++    S+Y   +L+  S Y+V +  + G   S 
Sbjct: 575  WTQAQGDVEFYQVLL-IHENVVIKNESISSETSRYSFHSLKSGSLYSVVVTTVSGGISSR 633

Query: 1077 KATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPRE--VTSD 1134
            +      T+    S    N       + ++W  AP       V  S  G+  +   +   
Sbjct: 634  QVVVEGRTVPSSVSGVTVNNSGRNDYLSVSWLLAPGDVDNYEVTLSHDGKVVQSLVIAKS 693

Query: 1135 SGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVS 1194
                  S LTPG  Y  TI       E  +    + V       ++   A  D   L VS
Sbjct: 694  VRECSFSSLTPGRLYTVTITTRSGKYENHSFSQERTVPDKVQGVSVSNSARSD--YLRVS 751

Query: 1195 WERSTTPDITGYRITTTPTNGQQGNSLE-EVVHADQSSCTFDNLSPGLEYNVSVYTVKDD 1253
            W  + T D   Y +T    N    N ++ + +   ++ C F  L PG  Y+V+V T    
Sbjct: 752  WVHA-TGDFDHYEVTIKNKN----NFIQTKSIPKSENECVFVQLVPGRLYSVTVTTKSGQ 806

Query: 1254 KESVPISD-TIIPEVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIF 1312
             E+    +   IPE   + DL+  + +   + + W+  N   +  Y I ++     + +F
Sbjct: 807  YEANEQGNGRTIPE--PVKDLTLRNRSTEDLHVTWSGANGD-VDQYEIQLLF--NDMKVF 861

Query: 1313 EDF-VDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAVPPPTDLRFTNIGP 1371
              F + ++   Y  T L PG  Y I V+T+   G+   +   +   V  P+ ++  +I P
Sbjct: 862  PPFHLVNTATEYRFTSLTPGRQYKILVLTI--SGDVQQSAFIEGFTV--PSAVKNIHISP 917

Query: 1372 ----DTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVV 1427
                D++ V W P    D+ ++ V  S  ++ + V   +I           L  G +Y +
Sbjct: 918  NGATDSLTVNWTPGGG-DVDSYTV--SAFRHSQKVDSQTIPKHVFEHTFHRLEAGEQYQI 974

Query: 1428 SVSSVYEQHESTPLRGR-QKTGLDSPTGID--FSDITANSFT--VHWIAPRATITGYRIR 1482
             ++SV     S  L+ +    G   P  +    +D   +S++  V W         Y I 
Sbjct: 975  MIASV-----SGSLKNQINVVGRTVPASVQGVIADNAYSSYSLIVSWQKAAGVAERYDIL 1029

Query: 1483 HHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVP 1542
               E+     R    P +       +LTPG +Y + I+ ++G   S     +  TV    
Sbjct: 1030 LLTEN-GILLRNTSEPATTKQHKFEDLTPGKKYKIQILTVSGGLFSKEAQTEGRTVPAAV 1088

Query: 1543 RDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPG 1602
             DL +   +   L   W A    + +Y I      GN   +    P  +S  +   L  G
Sbjct: 1089 TDLRITENSTRHLSFRWTASEGELSWYNIFLYNPDGNLQERAQVDPLVQS-FSFQNLLQG 1147

Query: 1603 VDYTITVYAVTGRGDSPA----SSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSS 1658
              Y + +   +G   + +     + P S+++     + S    TD    S+   W P+S 
Sbjct: 1148 RMYKMVIVTHSGELSNESFIFGRTVPASVSHL----RGSNRNTTD----SLWFNWSPASG 1199

Query: 1659 PVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE-SQPLVQ 1717
                Y +     N  G  K      D TE   +GL P  +YV+ V     SG+ S  +  
Sbjct: 1200 DFDFYELILYNPN--GTKKENWKDKDLTEWRFQGLVPGRKYVLWVVTH--SGDLSNKVTA 1255

Query: 1718 TAVTNIDRPKGLAFTDVDVDSIKIAWESPQG--QVSRYRVTYSSPEDGIHELFPAPDGEE 1775
             + T    P  ++F D+   S+ I W+ P      + + + +  P D +    P  + + 
Sbjct: 1256 ESRTAPSPPSLMSFADIANTSLAITWKGPPDWTDYNDFELQW-LPRDALTVFNPYNNRKS 1314

Query: 1776 DTAELQGLRPGSEYTVSVVALHDD---MESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQ 1832
            +   + GLRPG  Y  +V  +  D     S+P+ G+  T      +L       T+++  
Sbjct: 1315 EGRIVYGLRPGRSYQFNVKTVSGDSWKTYSKPIFGSVRTKPDKIQNLHCRPQNSTAIACS 1374

Query: 1833 WTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTS 1892
            W PP+    GY +     +         L  + S + +  L+   +Y VS+      +TS
Sbjct: 1375 WIPPDSDFDGYSIECRKMDTQEVEFSRKLEKEKSLLNIMMLVPHKRYLVSIKVQSAGMTS 1434

Query: 1893 RPAQGVVTTL--ENVSPPRRARVTD--------ATETTITISWRTKTE-TITGFQVDAVP 1941
               +    T+      PP   RV +        +   T+  SW + T   +  F V    
Sbjct: 1435 EVVEDSTITMIDRPPPPPPHIRVNEKDVLISKSSINFTVNCSWFSDTNGAVKYFTVVVRE 1494

Query: 1942 ANGQTPIQRTIKPDVRSY 1959
            A+G   ++   +  + SY
Sbjct: 1495 ADGSDELKPEQQHPLPSY 1512



 Score =  145 bits (365), Expect = 6e-34
 Identities = 235/1152 (20%), Positives = 447/1152 (38%), Gaps = 110/1152 (9%)

Query: 967  LSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITG 1026
            L  G  Y F++ ++    E + +  Q      A   +     T +++ V WTP   ++T 
Sbjct: 85   LQAGTIYNFRIISLD---EERTVVLQTDPLPPARFGVSKEKTTSTSLHVWWTPSSGKVTS 141

Query: 1027 YRLTV--GLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTT 1084
            Y + +     ++ Q  Q     S ++Y   NL   S+Y +++ A+ G + S      F+ 
Sbjct: 142  YEVQLFDENNQKIQGVQIQESTSWNEYTFFNLTAGSKYNIAITAVSGGKRS------FSV 195

Query: 1085 LQPGSSIPPYNTEVTETT----IVITWTPAPRI--GFKLGVRPS----QGGEAPREVTSD 1134
               GS++P    ++  +T    ++I+W+        ++L +        GG   +  TS 
Sbjct: 196  YTNGSTVPSPVKDIGISTKANSLLISWSHGSGNVERYRLMLMDKGILVHGGVVDKHATS- 254

Query: 1135 SGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVS 1194
                   GLTPG  Y+Y + V+ +           V T     +NL +  +     L V 
Sbjct: 255  ---YAFHGLTPG--YLYNLTVMTEAAGLQNYRWKLVRTAPMEVSNLKVTNDGSLTSLKVK 309

Query: 1195 WERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCT-FDNLSPGLEYNVSVYTVKDD 1253
            W+R    ++  Y IT +     +G   E  V A   + T F  L PG  Y V+V  V  +
Sbjct: 310  WQRPPG-NVDSYNITLS----HKGTIKESRVLAPWITETHFKELVPGRLYQVTVSCVSGE 364

Query: 1254 --KESVPISDTIIPEVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGEGIPI 1311
               + + +  T   +V  L   +   +   S+ + W+P  +     YRI +    + + +
Sbjct: 365  LSAQKMAVGRTFPDKVANLEANNNGRMR--SLVVSWSP-PAGDWEQYRILLF--NDSVVL 419

Query: 1312 FEDFVDSSVGYYTV--TGLEPGIDYDISVITLINGGESAPTTLTQQTAVPPPT-DLRFTN 1368
                V      Y +  TGL PG  Y++ VI  +  G    +   Q   VP     LR  +
Sbjct: 420  LNITVGKEETQYVMDDTGLVPGRQYEVEVI--VESGNLKNSERCQGRTVPLAVLQLRVKH 477

Query: 1369 IGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVS 1428
                ++ + W  P + +   +++  S    +  +   S+S        T+L+PG +Y+ +
Sbjct: 478  ANETSLSIMWQTPVA-EWEKYII--SLADRDLLLIHKSLSKDAKEFTFTDLVPGRKYMAT 534

Query: 1429 VSSVY-EQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEH 1487
            V+S+  +   S+ ++GR      +   +    +T++ FT +W   +  +  Y++    E+
Sbjct: 535  VTSISGDLKNSSSVKGRTVPAQVTDLHVANQGMTSSLFT-NWTQAQGDVEFYQVLLIHEN 593

Query: 1488 FSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEV 1547
                 + + +    +  +  +L  G+ Y V +  ++G   S  ++ +  TV      + V
Sbjct: 594  VV--IKNESISSETSRYSFHSLKSGSLYSVVVTTVSGGISSRQVVVEGRTVPSSVSGVTV 651

Query: 1548 VAATPTSLL-ISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYT 1606
              +     L +SW      V  Y +T    G    VQ   +  S    + S L PG  YT
Sbjct: 652  NNSGRNDYLSVSWLLAPGDVDNYEVTLSHDG--KVVQSLVIAKSVRECSFSSLTPGRLYT 709

Query: 1607 ITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTD-VQDNSISVKWLPSSSPVTGYRV 1665
            +T+   +G+ ++ + S+      RT  DK   + V++  + + + V W+ ++     Y V
Sbjct: 710  VTITTRSGKYENHSFSQE-----RTVPDKVQGVSVSNSARSDYLRVSWVHATGDFDHYEV 764

Query: 1666 TTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDR 1725
            T   KN     +TK+    + E     L P   Y V+V  +  SG+ +   Q     I  
Sbjct: 765  TIKNKNNF--IQTKSIPKSENECVFVQLVPGRLYSVTVTTK--SGQYEANEQGNGRTIPE 820

Query: 1726 P-KGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTA---ELQ 1781
            P K L   +   + + + W    G V +Y +     +    ++FP P    +TA      
Sbjct: 821  PVKDLTLRNRSTEDLHVTWSGANGDVDQYEIQLLFND---MKVFP-PFHLVNTATEYRFT 876

Query: 1782 GLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPT----SLSAQWTPPN 1837
             L PG +Y + V+ +  D++    I         P+ +K   ++P     SL+  WTP  
Sbjct: 877  SLTPGRQYKILVLTISGDVQQSAFI----EGFTVPSAVKNIHISPNGATDSLTVNWTPGG 932

Query: 1838 VQLTGYRV-----------RVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYAL 1886
              +  Y V           +  PK           A +   ++++ +  + K +++V   
Sbjct: 933  GDVDSYTVSAFRHSQKVDSQTIPKHVFEHTFHRLEAGEQYQIMIASVSGSLKNQINVVG- 991

Query: 1887 KDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQT 1946
                     QGV+                 +  ++ +SW+        + +  +  NG  
Sbjct: 992  --RTVPASVQGVIAD------------NAYSSYSLIVSWQKAAGVAERYDILLLTENGIL 1037

Query: 1947 PIQRTIKP-DVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLAT 2005
             ++ T +P   + +    L PG  YKI + T++    S     +  T   A ++LR    
Sbjct: 1038 -LRNTSEPATTKQHKFEDLTPGKKYKIQILTVSGGLFSKEAQTEGRTVPAAVTDLRITEN 1096

Query: 2006 TPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVI 2065
            +   L   W      ++ Y I    P    +E   +  P V   +   L  G  Y + ++
Sbjct: 1097 STRHLSFRWTASEGELSWYNIFLYNPDGNLQERA-QVDPLVQSFSFQNLLQGRMYKMVIV 1155

Query: 2066 ALKNNQKSEPLI 2077
                   +E  I
Sbjct: 1156 THSGELSNESFI 1167



 Score = 35.4 bits (80), Expect = 0.69
 Identities = 37/194 (19%), Positives = 76/194 (39%), Gaps = 25/194 (12%)

Query: 628  IQWNAPQP-SHISKYILRWRPKNSV---GRWKEATIPGHLNSYTIKGLKPGVVYEGQLIS 683
            I W  P   +  + + L+W P++++     +      G +    + GL+PG  Y+  + +
Sbjct: 1279 ITWKGPPDWTDYNDFELQWLPRDALTVFNPYNNRKSEGRI----VYGLRPGRSYQFNVKT 1334

Query: 684  IQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSA 743
            +     +  ++  F +  T      N           L    ++ T I  S     W+  
Sbjct: 1335 VSGDSWKTYSKPIFGSVRTKPDKIQN-----------LHCRPQNSTAIACS-----WIPP 1378

Query: 744  SDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLIL 803
                 G+ +E    +  +      L    + +NI  L+P ++Y+V++ ++   G  S ++
Sbjct: 1379 DSDFDGYSIECRKMDTQEVEFSRKLEKEKSLLNIMMLVPHKRYLVSI-KVQSAGMTSEVV 1437

Query: 804  STSQTTAPDAPPDP 817
              S  T  D PP P
Sbjct: 1438 EDSTITMIDRPPPP 1451


>gi|110349719 titin isoform N2-A [Homo sapiens]
          Length = 33423

 Score =  175 bits (444), Expect = 4e-43
 Identities = 382/1656 (23%), Positives = 623/1656 (37%), Gaps = 244/1656 (14%)

Query: 630   WNAPQPSHISK---YILRWRPKNSVG--RWKEA--TIPGHLNSYTIKGLKPGVVYEGQLI 682
             W+AP     SK   YI+  +P + VG  RW +   TI    N +T+  L  G  YE +++
Sbjct: 28959 WSAPAYDGGSKVVGYIIERKPVSEVGDGRWLKCNYTIVSD-NFFTVTALSEGDTYEFRVL 29017

Query: 683   SIQQYGHQEVTRFDFTTTSTST-PVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWV 741
             +    G         +  S ST PVT                  + VT    S  V+   
Sbjct: 29018 AKNAAGV-------ISKGSESTGPVTCRDEYAPPKAELDARLHGDLVTIRAGSDLVL--- 29067

Query: 742   SASDTVSGFRVEYELS-EEGDEP---------QYLDLPSTATSVNIPDLLPGRKYIVNVY 791
                D   G + E ++   +GD+          QY    +TA  +   D     KY + V 
Sbjct: 29068 ---DAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAV-IKFCDRSDSGKYTLTVK 29123

Query: 792   QISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ----APITGYRIVYSP 847
               S  G +++ +      +P      TV +V      + WS PQ    A IT Y +    
Sbjct: 29124 NAS--GTKAVSVMVKVLDSPGPCGKLTVSRVTQEKCTLAWSLPQEDGGAEITHYIVERRE 29181

Query: 848   S-------VEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG 900
             +       VEG    L       S  ++ L    +Y   + AV +     PV  + E   
Sbjct: 29182 TSRLNWVIVEGECPTL-------SYVVTRLIKNNEYIFRVRAVNKYGPGVPV--ESEPIV 29232

Query: 901   TPRSDTVPSPRDL-QFVEVTDVKVTIMWTPPES----AVTGYRVDVIPV-NLPGEHGQRL 954
                S T+PSP  + + V      + I WT PES     ++ Y VD     +L      + 
Sbjct: 29233 ARNSFTIPSPPGIPEEVGTGKEHIIIQWTKPESDGGNEISNYLVDKREKKSLRWTRVNKD 29292

Query: 955   PISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNL-------QFVN 1007
              +  +T  +VT L  G  Y F+V AV+    S+P  A        P+         + V+
Sbjct: 29293 YVVYDTRLKVTSLMEGCDYQFRVTAVNAAGNSEPSEASNFISCREPSYTPGPPSAPRVVD 29352

Query: 1008  ETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSV--SKYPLRNLQPASE 1061
              T  ++ + WT P       I GY L +      Q  + +   ++  +++ + +L+   +
Sbjct: 29353 TTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDTDQWYRVHTNATIRNTEFTVPDLKMGQK 29412

Query: 1062  YT--VSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGV 1119
             Y+  V+ V +KG  E  ++      ++P   I   + E+ +    +  T   R G  L +
Sbjct: 29413 YSFRVAAVNVKGMSEYSES---IAEIEPVERIEIPDLELADD---LKKTVTIRAGASLRL 29466

Query: 1120  RPSQGGEAPREVT-----SDSGSIVVSGLTPGVEYV------------YTIQVLRDGQER 1162
               S  G  P  +T      D  S  +   T     +            YTI+      ++
Sbjct: 29467 MVSVSGRPPPVITWSKQGIDLASRAIIDTTESYSLLIVDKVNRYDAGKYTIEAENQSGKK 29526

Query: 1163  DAPIVNKVV-TPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSL 1221
              A ++ KV  TP   P+    E + D+  +T++WE    P I G      P N       
Sbjct: 29527 SATVLVKVYDTPGPCPSVKVKEVSRDS--VTITWE---IPTIDG----GAPVNNYIVEKR 29577

Query: 1222  EEVVHA-----DQSSCTFDNLSPGLEYNVSVYTVKDDK-----ESVPISDTI-IPEVPQL 1270
             E  + A      + S T   +S  +E  +  + V  +      E    SD + + EVP +
Sbjct: 29578 EAAMRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYGIGEPCETSDAVLVSEVPLV 29637

Query: 1271  -TDLSFVDITDSSIGLRW-TPL--NSSTIIGYRITVVAAGEGIPIFEDFVDSSVGYYTVT 1326
                L  VD+T S++ L W  PL    S + GY +    AG    +    +  +V  +TVT
Sbjct: 29638 PAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGTERWMKVVTLKPTVLEHTVT 29697

Query: 1327  GLEPGIDYDISVITLINGGESAP----TTLT-QQTAVPPPTDLRFTNIGPDTMRV----- 1376
              L  G  Y   +      G S P    T +T Q   V P  DL  + +   T+ V     
Sbjct: 29698 SLNEGEQYLFRIRAQNEKGVSEPRETVTAVTVQDLRVLPTIDL--STMPQKTIHVPAGRP 29755

Query: 1377  -------TWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSV 1429
                       PPP+     F       ++E    E     +   +  T +    EY + +
Sbjct: 29756 VELVIPIAGRPPPAASW--FFAGSKLRESERVTVETHTKVAKLTIRETTIRDTGEYTLEL 29813

Query: 1430  SSVY-EQHESTPLRGRQKTGLDSPTG-IDFSDITANSFTVHWIAPR----ATITGYRIRH 1483
              +V     E+  +    K G   PTG I   +I A S T+ W  P     A ++GY +  
Sbjct: 29814 KNVTGTTSETIKVIILDKPG--PPTGPIKIDEIDATSITISWEPPELDGGAPLSGYVVEQ 29871

Query: 1484  HPEHFSG-RPREDRVPHSRNSITLTNLTPGTEYVVSIVALN----GREESPLLIGQQST- 1537
                H  G  P  + V  +R++   T LT G EYV  + A N    G      +I  +S+ 
Sbjct: 29872 RDAHRPGWLPVSESV--TRSTFKFTRLTEGNEYVFRVAATNRFGIGSYLQSEVIECRSSI 29929

Query: 1538  -VSDVPRDLEVVAATPTSLLISWDAP----AVTVRYYRITYGETGGNSPVQEFTVPGSKS 1592
              +   P  L++   +   + ++W  P       V  Y +   E   +  V+   VP + +
Sbjct: 29930 RIPGPPETLQIFDVSRDGMTLTWYPPEDDGGSQVTGYIVERKEVRADRWVRVNKVPVTMT 29989

Query: 1593  TATISGLKPGVDYTITVYAVTGRGDSPAS--SKPI-SINYRTEIDKPSQMQVTDVQDNSI 1649
                 +GL  G++Y   V A+  RG    S  SKPI +++      KP   +VTD    S+
Sbjct: 29990 RYRSTGLTEGLEYEHRVTAINARGSGKPSRPSKPIVAMDPIAPPGKPQNPRVTDTTRTSV 30049

Query: 1650  SVKWL----PSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYA 1705
             S+ W        S VTGY +     +    TK  T      E T+  L    EY   V A
Sbjct: 30050 SLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTKCNTTPTKIREYTLTHLPQGAEYRFRVLA 30109

Query: 1706  QNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDS-IKIAWESPQGQVSRYRVTYSSPEDGI 1764
              N  G  +P        +   + L + D ++D   +      QG V R  +        I
Sbjct: 30110 CNAGGPGEPAEVPGTVKV--TEMLEYPDYELDERYQEGIFVRQGGVIRLTIPIKGKPFPI 30167

Query: 1765  HELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMES------------QPLIGTQSTA 1812
              +     +G +D ++   +     +T  V+   D  +S            +  +  +   
Sbjct: 30168 CKW--TKEG-QDISKRAMIATSETHTELVIKEADRGDSGTYDLVLENKCGKKAVYIKVRV 30224

Query: 1813  IPAPTD----LKFTQVTPTSLSAQWTPP----NVQLTGYRV--RVTPKEKTGPMKEINLA 1862
             I +P      L++  +   S+   W PP       + GY +  R  PK        I+  
Sbjct: 30225 IGSPNSPEGPLEYDDIQVRSVRVSWRPPADDGGADILGYILERREVPK---AAWYTIDSR 30281

Query: 1863  PDSSSVVVSGLMVATKYEVSVYALKDTLTSRP--AQGVVTTLENVSPP----RRARVTDA 1916
                +S+VV GL    +Y   V A      S+P  ++  VT    ++PP        V D 
Sbjct: 30282 VRGTSLVVKGLKENVEYHFRVSAENQFGISKPLKSEEPVTPKTPLNPPEPPSNPPEVLDV 30341

Query: 1917  TETTITISW-RTKTE---TITGFQVDAVPANGQTPIQRT-IKPDVRSYTITGLQPGTDYK 1971
             T++++++SW R K +    +TG+ ++    +    ++    +     YT+TGL P  +Y+
Sbjct: 30342 TKSSVSLSWSRPKDDGGSRVTGYYIERKETSTDKWVRHNKTQITTTMYTVTGLVPDAEYQ 30401

Query: 1972  IYLYTLND------NARSSPVVI-DASTAIDAPSNLRFLATTPNSLLVSWQPPRA----R 2020
               +   ND      +  S PVV  D       P  L  L+ + +S+ + W+ P       
Sbjct: 30402 FRIIAQNDVGLSETSPASEPVVCKDPFDKPSQPGELEILSISKDSVTLQWEKPECDGGKE 30461

Query: 2021  ITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRK 2080
             I GY ++Y + G    +   + R    + TI GL   TEY   V A      S P     
Sbjct: 30462 ILGYWVEYRQSGDSAWKKSNKERIKDKQFTIGGLLEATEYEFRVFAENETGLSRP----- 30516

Query: 2081  KTVQKTPFVTHPGYDTGNGIQLPGTSGQQPSVGQQM 2116
                            T   I+   TSG+ P + ++M
Sbjct: 30517 -------------RRTAMSIKTKLTSGEAPGIRKEM 30539



 Score =  157 bits (398), Expect = 9e-38
 Identities = 342/1617 (21%), Positives = 590/1617 (36%), Gaps = 235/1617 (14%)

Query: 624   NSHPIQWNAPQP---SHISKYILRWRPKNSVGRWKEAT-IPGHLNSYTIKGLKPGVVYEG 679
             N+  + W  P     S I+ Y +  R K S+ RW  A   P       + GL+ G  YE 
Sbjct: 20586 NTATVSWKRPVDDGGSEITGYHVERREKKSL-RWVRAIKTPVSDLRCKVTGLQEGSTYEF 20644

Query: 680   QLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVS 739
             ++ +  + G    +              S++V  +   + P   ++  VT+ T  S  ++
Sbjct: 20645 RVSAENRAGIGPPSE------------ASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLA 20692

Query: 740   W----VSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVN---IPDLLPGRKYIVNVYQ 792
             W          ++G+ VE++  + GDE    D   TA  +    +PDL    KY   +  
Sbjct: 20693 WGKPHYDGGLEITGYVVEHQ--KVGDEAWIKDTTGTALRITQFVVPDLQTKEKYNFRISA 20750

Query: 793   ISEDGE-QSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWS---RPQAPITGYRIVYSPS 848
             I++ G  +  ++   +    +  PD  +D     ++VVR     R   PI G     +P 
Sbjct: 20751 INDAGVGEPAVIPDVEIVEREMAPDFELDAELRRTLVVRAGLSIRIFVPIKGRP---APE 20807

Query: 849   VEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTV- 907
             V  +   +NL   AN      ++    + + I       ++   V+  E     +S  V 
Sbjct: 20808 VTWTKDNINLKNRAN------IENTESFTLLIIPECNRYDTGKFVMTIENPAGKKSGFVN 20861

Query: 908   ------PSP-RDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPGEHGQRLPI 956
                   P P  +L+  ++T   VT+ W  P     S +T Y V+                
Sbjct: 20862 VRVLDTPGPVLNLRPTDITKDSVTLHWDLPLIDGGSRITNYIVEKREATRKSYSTATTKC 20921

Query: 957   SRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDA----PTNLQFVNETDST 1012
              + T+ +VTGLS G  Y+F+V A +     +P    +  K       P +L  ++ T ST
Sbjct: 20922 HKCTY-KVTGLSEGCEYFFRVMAENEYGIGEPTETTEPVKASEAPSPPDSLNIMDITKST 20980

Query: 1013  VLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSVS-KYPLRNLQPASEYTVSLV 1067
             V + W  P+    ++ITGY   +   R+G  +  ++      +  +RNL    EYT  ++
Sbjct: 20981 VSLAWPKPKHDGGSKITGY--VIEAQRKGSDQWTHITTVKGLECVVRNLTEGEEYTFQVM 21038

Query: 1068  AIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWT-------------PAPRIG 1114
             A+     S         ++  + +P  +       +VI                P P + 
Sbjct: 21039 AVNSAGRSAPRESRPVIVKEQTMLPELDLRGIYQKLVIAKAGDNIKVEIPVLGRPKPTVT 21098

Query: 1115  FKLGVRP-SQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTP 1173
             +K G +   Q      E T+ S  + ++         Y +       E    I  +V   
Sbjct: 21099 WKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLTARNIVGEVGDVITIQVHDI 21158

Query: 1174  LSPPTNLHLEANPDTGVLTVSW---ERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQS 1230
               PPT         +  +T SW   E      I+ Y +    T+      L   V     
Sbjct: 21159 PGPPTGPIKFDEVSSDFVTFSWDPPENDGGVPISNYVVEMRQTDSTTWVELATTVIRTTY 21218

Query: 1231  SCTFDNLSPGLEYNVSVYTVKDDKESVPISDTII-----------PEVPQLTDLSFVDIT 1279
               T   L+ GLEY   V           I+   I           P  PQ+T      +T
Sbjct: 21219 KAT--RLTTGLEYQFRVKAQNRYGVGPGITSACIVANYPFKVPGPPGTPQVTA-----VT 21271

Query: 1280  DSSIGLRW-TPLNS--STIIGYRITVVAAGEGIPIFEDFVDSSV---GYYTVTGLEPGID 1333
               S+ + W  PL+   S I+GY    V   E   I    V  ++     +  +GL  GI 
Sbjct: 21272 KDSMTISWHEPLSDGGSPILGYH---VERKERNGILWQTVSKALVPGNIFKSSGLTDGIA 21328

Query: 1334  YDISVITLINGGESAPTTLTQQTA----VPPPTDLRFTNIGPDTMRVTWAPPP---SIDL 1386
             Y+  VI     G+S P+  ++       + PP      NI   T+ + WA P       +
Sbjct: 21329 YEFRVIAENMAGKSKPSKPSEPMLALDPIDPPGKPVPLNITRHTVTLKWAKPEYTGGFKI 21388

Query: 1387  TNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQ- 1445
             T+++V    + N   +     +  +N   ++ L     Y   V +       +P      
Sbjct: 21389 TSYIVEKRDLPNGRWLKANFSNILENEFTVSGLTEDAAYEFRVIAKNAAGAISPPSEPSD 21448

Query: 1446  ----KTGLDSP---TGIDFSDIT----ANSF------------TVHWIAPRATITGY-RI 1481
                 +  +++P     + F D        +F            T+ W      + G  ++
Sbjct: 21449 AITCRDDVEAPKIKVDVKFKDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKL 21508

Query: 1482  RHHPEHFSGR-PREDRVPHSRNSITLTNLTPG--TEYVVSIVALN--GREESPLLIGQQS 1536
                   FS     +D       + TLT   PG   +++ ++  L+  G  E PL + +  
Sbjct: 21509 EIKIADFSTNLVNKDSTRRDSGAYTLTATNPGGFAKHIFNVKVLDRPGPPEGPLAVTE-- 21566

Query: 1537  TVSDVPRDLEVVAATPTSLLISWDAP----AVTVRYYRITYGETGGNSPVQEFTVPGSKS 1592
                           T    ++SW  P       + +Y +   ET   +    +T   S+ 
Sbjct: 21567 -------------VTSEKCVLSWFPPLDDGGAKIDHYIVQKRETSRLA----WTNVASEV 21609

Query: 1593  TAT---ISGLKPGVDYTITVYAVTGRG-DSPASSKPI-SINYRTEIDKPSQMQVTDVQDN 1647
               T   ++ L  G +Y   V AV   G   P  S+P+ ++N     D P   +VT +  +
Sbjct: 21610 QVTKLKVTKLLKGNEYIFRVMAVNKYGVGEPLESEPVLAVNPYGPPDPPKNPEVTTITKD 21669

Query: 1648  SISVKW----LPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSV 1703
             S+ V W        S +  Y V    K G    K            + GL    EY   +
Sbjct: 21670 SMVVCWGHPDSDGGSEIINYIVERRDKAGQRWIKCNKKTLTDLRYKVSGLTEGHEYEFRI 21729

Query: 1704  YAQNPSGESQPLVQT-------AVTNIDRPKGLAFTDVDVDSIKIAWESP----QGQVSR 1752
              A+N +G S P   +        V     P      D    SI IAW  P      +++ 
Sbjct: 21730 MAENAAGISAPSPTSPFYKACDTVFKPGPPGNPRVLDTSRSSISIAWNKPIYDGGSEITG 21789

Query: 1753  YRVTYSSPEDGIHELFPAPDGEEDTA-ELQGLRPGSEYTVSVVALHDDMESQPLI--GT- 1808
             Y V  + PE+   ++   P G + T+  + GL    EY + + A++ +   +P +  GT 
Sbjct: 21790 YMVEIALPEEDEWQIVTPPAGLKATSYTITGLTENQEYKIRIYAMNSEGLGEPALVPGTP 21849

Query: 1809  --QSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSS 1866
               +   +P   +L        ++ A  T          +R+    K  P  E+  A D  
Sbjct: 21850 KAEDRMLPPEIELDADLRKVVTIRACCT----------LRLFVPIKGRPAPEVKWARDHG 21899

Query: 1867  SVVVSGLMVAT------------KYEVSVYAL--KDTLTSRPAQGVVTTLENVSPPRRAR 1912
               +    + +T            +++   Y L  +++  S+ A   V  L+   PP+  +
Sbjct: 21900 ESLDKASIESTSSYTLLIVGNVNRFDSGKYILTVENSSGSKSAFVNVRVLDTPGPPQDLK 21959

Query: 1913  VTDATETTITISWRTKT----ETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGT 1968
             V + T+T++T++W          I  + V+   +  +            S+ +  LQ G 
Sbjct: 21960 VKEVTKTSVTLTWDPPLLDGGSKIKNYIVEKRESTRKAYSTVATNCHKTSWKVDQLQEGC 22019

Query: 1969  DYKIYLYTLNDNARSSPVVIDASTAIDA------PSNLRFLATTPNSLLVSWQPPR---- 2018
              Y  Y   L +N     +  + + ++ A      P  +  +  T NS+ +SW+ P     
Sbjct: 22020 SY--YFRVLAENEYGIGLPAETAESVKASERPLPPGKITLMDVTRNSVSLSWEKPEHDGG 22077

Query: 2019  ARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEP 2075
             +RI GYI++ +  GS         +  VTEATITGL  G EY+  V A      S+P
Sbjct: 22078 SRILGYIVEMQTKGSDKWATCATVK--VTEATITGLIQGEEYSFRVSAQNEKGISDP 22132



 Score =  146 bits (368), Expect = 3e-34
 Identities = 363/1662 (21%), Positives = 600/1662 (36%), Gaps = 237/1662 (14%)

Query: 612   VEVFITETPSQPNSHPIQ----------WNAPQP---SHISKYILRWRPKNSVGRWKEAT 658
             VEV + + P  P +  I           WN P+    S I+ Y++  R  +S   W + +
Sbjct: 13776 VEVNVLDKPGPPAAFDITDVTNESCLLTWNPPRDDGGSKITNYVVERRATDSEV-WHKLS 13834

Query: 659   IPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPF 718
                   ++    L P   Y  ++ +   YG  E             PV ++ +T +    
Sbjct: 13835 STVKDTNFKATKLIPNKEYIFRVAAENMYGVGE-------------PVQASPITAKYQFD 13881

Query: 719   SPLVATSESVTEITASSFVVSWVSASDT----VSGFRVEYELSEEGDEPQYLDLPSTATS 774
              P   T    ++IT  +  ++W    D     ++G+ VE    +     +   +P   T+
Sbjct: 13882 PPGPPTRLEPSDITKDAVTLTWCEPDDDGGSPITGYWVERLDPDTDKWVRCNKMPVKDTT 13941

Query: 775   VNIPDLLPGRKYIVNVY--QISEDGEQSL----ILSTSQTTAPDAPPDPTVDQVDDTSIV 828
               +  L   +KY   V    ++  G+ S     IL       P  P  PTV  V  TS+ 
Sbjct: 13942 YRVKGLTNKKKYRFRVLAENLAGPGKPSKSTEPILIKDPIDPPWPPGKPTVKDVGKTSVR 14001

Query: 829   VRWSRPQ----APITGY--RIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYA 882
             + W++P+    A I  Y   ++ + + E       +P T +   L  L  G +Y+  + A
Sbjct: 14002 LNWTKPEHDGGAKIESYVIEMLKTGTDEWVRVAEGVPTTQH--LLPGLMEGQEYSFRVRA 14059

Query: 883   VEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYR 938
             V +  ES P           +      PR L+ + +T     + WT PE    S +T Y 
Sbjct: 14060 VNKAGESEPSEPSDPVLCREKLYPPSPPRWLEVINITKNTADLKWTVPEKDGGSPITNYI 14119

Query: 939   VDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSH-GR------ESKPLTA 991
             V+   V   G       + ++T   VT L+ G  Y F+V A +  G+      E   L  
Sbjct: 14120 VEKRDVRRKGWQTVDTTV-KDTKCTVTPLTEGSLYVFRVAAENAIGQSDYTEIEDSVLAK 14178

Query: 992   QQTTKLDAPTNLQFVNETDSTVLVRWTPPR--AQITGYRLTVGLTRRGQPRQYNVGPSVS 1049
                T    P  L  V+ T   V ++W PP+        R  +    R   R    G +  
Sbjct: 14179 DTFTTPGPPYALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKERLGTRWVKAGKTAG 14238

Query: 1050  KYPLRNLQPASEYTVSLVAIKGNQES-----PKATGVFTTLQPGS-SIPPYNTEVTET-- 1101
                   +    E T     ++   E+      + T + +   P S   PP +  VT+   
Sbjct: 14239 PDCNFRVTDVIEGTEVQFQVRAENEAGVGHPSEPTEILSIEDPTSPPSPPLDLHVTDAGR 14298

Query: 1102  -TIVITWTP------APRIGFKLGVRPSQGGEAPREVTS----DSGSIVVSGLTPGVEYV 1150
               I I W P      +P IG+ + + P  G E    V S    D    V  G+ P  EYV
Sbjct: 14299 KHIAIAWKPPEKNGGSPIIGYHVEMCP-VGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYV 14357

Query: 1151  YTIQVLRD-GQERDAPIVNKVVT--PLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYR 1207
               ++ +   G    + I   VV   P   PT + LE +    ++ +  E+ + P    +R
Sbjct: 14358 LRVRAVNAIGVSEPSEISENVVAKDPDCKPT-IDLETH---DIIVIEGEKLSIP--VPFR 14411

Query: 1208  ITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEY------NVSVYTV----KDDKESV 1257
                 PT     +  +EV  +D+ +   D++S  LE       +  +YT+    K    + 
Sbjct: 14412 AVPVPTVSWHKDG-KEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATA 14470

Query: 1258  PISDTIIPEVPQLTDLSFVDITDSSIGLRWTPL---NSSTIIGYRITVVAAGEG--IPIF 1312
              I+  +I       D+   DIT SS  L W P      + I+ Y +    AG    IP+ 
Sbjct: 14471 SINVKVIGLPGPCKDIKASDITKSSCKLTWEPPEFDGGTPILHYVLERREAGRRTYIPVM 14530

Query: 1313  EDFVDSSVGYYTVTGLEPGIDY--DISVITLINGGESAP---TTLTQQTAVP--PPTDLR 1365
                   S   +TV  L P  +Y   +  +  + GGE        + Q    P  PP D+ 
Sbjct: 14531 SGENKLS---WTVKDLIPNGEYFFRVKAVNKVGGGEYIELKNPVIAQDPKQPPDPPVDVE 14587

Query: 1366  FTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLT----NLLP 1421
               N   + M +TW  PP  D  + ++ Y   K  +              +LT     L  
Sbjct: 14588 VHNPTAEAMTITW-KPPLYDGGSKIMGYIIEKIAKGEERWKRCNEHLVPILTYTAKGLEE 14646

Query: 1422  GTEYVVSVSSVYEQHESTPLRGRQKT----GLDSP---------------TGIDFSDITA 1462
             G EY   V +      S P R    T     +D+P                 +D S   +
Sbjct: 14647 GKEYQFRVRAENAAGISEPSRATPPTKAVDPIDAPKVILRTSLEVKRGDEIALDASISGS 14706

Query: 1463  NSFTVHWIAPRATITGYRIRHHPEHFSGRPR------EDRVPHSRNSITLTNLTPGTE-- 1514
                T+ WI     I    I+        R +      E  V      +++ N   G    
Sbjct: 14707 PYPTITWIKDENVIVPEEIKKRAAPLVRRRKGEVQEEEPFVLPLTQRLSIDNSKKGESQL 14766

Query: 1515  ------------YVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAP 1562
                         Y++ +   +G  ++P  +    T    P +        TS+L  W+ P
Sbjct: 14767 RVRDSLRPDHGLYMIKVENDHGIAKAPCTVSVLDTPGP-PINFVFEDIRKTSVLCKWEPP 14825

Query: 1563  -----AVTVRYYRITYGETGGNSPVQEFTVPGS---KSTATISGLKPGVDYTITVYAVTG 1614
                  +  + Y   T  +     P  E+ V  S       +++ L  G +Y   V A   
Sbjct: 14826 LDDGGSEIINY---TLEKKDKTKPDSEWIVVTSTLRHCKYSVTKLIEGKEYLFRVRAENR 14882

Query: 1615  RGDS-PASSKP-ISINYRTEIDKPSQMQVTDVQDNSISVKW---LPSSSPVTGYRVTTTP 1669
              G   P  SKP ++ +     D P +  V DV  NS+ VKW     + SP+ GY +    
Sbjct: 14883 FGPGPPCVSKPLVAKDPFGPPDAPDKPIVEDVTSNSMLVKWNEPKDNGSPILGYWLEKRE 14942

Query: 1670  KNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSG------ESQPLVQTAVTNI 1723
              N    ++   +  +  +  ++GL   + YV  V A+N +G       S P       + 
Sbjct: 14943 VNSTHWSRVNKSLLNALKANVDGLLEGLTYVFRVCAENAAGPGKFSPPSDPKTAHDPISP 15002

Query: 1724  DRPKGLAFTDVDVDSIKIAWESPQ----GQVSRYRVTYSSPEDGIHELFPAPDGEEDTAE 1779
               P     TD    +I++ WE P     G++  Y V       G +E     +      +
Sbjct: 15003 PGPPIPRVTDTSSTTIELEWEPPAFNGGGEIVGYFV--DKQLVGTNEWSRCTEKMIKVRQ 15060

Query: 1780  --LQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPN 1837
               ++ +R G++Y + V A++   E  P   TQ   +  P +    ++  +          
Sbjct: 15061 YTVKEIREGADYKLRVSAVNAAGEGPP-GETQPVTVAEPQEPPAVELDVS------VKGG 15113

Query: 1838  VQLTGYRVRVTPKEKTG---PMKEINLAP---DSSSVVVSGLMVATKYEVSVYALKDTLT 1891
             +Q+   +    P   TG   P K         D   VV+    V TK E+    +KD L 
Sbjct: 15114 IQIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKDRVVIDN--VGTKSEL---IIKDALR 15168

Query: 1892  SRPAQGVVTTLENVS---PPRRARVTDATETTI------------TISWRTKTE----TI 1932
                 + V+T   +        R  V D     +             ++W    +     I
Sbjct: 15169 KDHGRYVITATNSCGSKFAAARVEVFDVPGPVLDLKPVVTNRKMCLLNWSDPEDDGGSEI 15228

Query: 1933  TGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDAST 1992
             TGF ++   A   T  ++ I+ +     ITGL  G +YK  +   N      PV I    
Sbjct: 15229 TGFIIERKDAKMHT-WRQPIETERSKCDITGLLEGQEYKFRVIAKNKFGCGPPVEIGPIL 15287

Query: 1993  AID------APSNLRFLATTPNSLLVSWQPPRAR----ITGYIIKYEKPGSPPREVVPRP 2042
             A+D      +P  L +   T +++ + W+ PR+     I GYII+  +   P  E V + 
Sbjct: 15288 AVDPLGPPTSPERLTYTERTKSTITLDWKEPRSNGGSPIQGYIIEKRRHDKPDFERVNKR 15347

Query: 2043  RPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQ 2084
                 T   +  L+    Y   V A+    +SEP +     +Q
Sbjct: 15348 LCPTTSFLVENLDEHQMYEFRVKAVNEIGESEPSLPLNVVIQ 15389



 Score =  144 bits (362), Expect = 1e-33
 Identities = 288/1427 (20%), Positives = 522/1427 (36%), Gaps = 163/1427 (11%)

Query: 696   DFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYE 755
             D+T T+ ++  + +          P    S  + ++ +   ++SW    +        Y 
Sbjct: 19365 DYTITAENSSGSKSATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYI 19424

Query: 756   LSE-EGDEPQYLDLPSTA--TSVNIPDLLPGRKY-----IVNVYQISEDGEQSLILSTSQ 807
             + + E   P +  + +T   TS ++  L+ G +Y       N Y + +       ++ + 
Sbjct: 19425 VDKRETSRPNWAQVSATVPITSCSVEKLIEGHEYQFRICAENKYGVGDPVFTEPAIAKNP 19484

Query: 808   TTAPDAPPDPTVDQVDDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNL-PETA 862
                P     P +  +    + V W  P     +PITGY +    +   + T++N  P   
Sbjct: 19485 YDPPGRCDPPVISNITKDHMTVSWKPPADDGGSPITGYLLEKRETQAVNWTKVNRKPIIE 19544

Query: 863   NSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVK 922
              ++  + LQ G +Y   + A+ +     P    +             P   +  + T   
Sbjct: 19545 RTLKATGLQEGTEYEFRVTAINKAGPGKPSDASKAAYARDPQYPPGPPAFPKVYDTTRSS 19604

Query: 923   VTIMWTPPE----SAVTGYRVDVIPVNLPGEHGQRLPIS-RNTFAEVTGLSPGVTYYFKV 977
             V++ W  P     S + GY V+V   +        LP + + T  EVTGL     Y F+V
Sbjct: 19605 VSLSWGKPAYDGGSPIIGYLVEVKRADSDNWVRCNLPQNLQKTRFEVTGLMEDTQYQFRV 19664

Query: 978   FAVSHGRESKP-----------LTAQQTTKLDAPTNLQFVNETDST----VLVRWTPPRA 1022
             +AV+    S P           +      +LDA      +     T    V V+  PP  
Sbjct: 19665 YAVNKIGYSDPSDVPDKHYPKDILIPPEGELDADLRKTLILRAGVTMRLYVPVKGRPP-P 19723

Query: 1023  QITGYRLTVGLTRR-GQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGV 1081
             +IT  +  V L  R G   +     +  +    N   A +Y ++L    G +E      V
Sbjct: 19724 KITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKYILTLENSCGKKEYTIVVKV 19783

Query: 1082  FTTLQPGSSIPPYNTEVTETTIVITWTP------APRIGFKLGVRPSQGGEAPREVTSDS 1135
               T  PG  +     E+++ +  +TW P      +P I + +  R ++        T  S
Sbjct: 19784 LDT--PGPPVNVTVKEISKDSAYVTWEPPIIDGGSPIINYVVQKRDAERKSWSTVTTECS 19841

Query: 1136  -GSIVVSGLTPGVEYVYTIQVLRD------GQERDAPIVNKVVTPLSPPTNLHLEANPDT 1188
               S  V+ L  G  Y + +    +      G+ RDA  V    TP  P  +L + +   +
Sbjct: 19842 KTSFRVANLEEGKSYFFRVFAENEYGIGDPGETRDA--VKASQTP-GPVVDLKVRSVSKS 19898

Query: 1189  GVLTVSWERSTTPD---ITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNV 1245
                ++ W++  +     I GY +        + N  + V+ +     +  +L+ G EY  
Sbjct: 19899 S-CSIGWKKPHSDGGSRIIGYVVDFL----TEENKWQRVMKSLSLQYSAKDLTEGKEYTF 19953

Query: 1246  SVYTVKDDKESVPISDTIIP---------EVPQLTDLSFVDITDSSIGLR---------- 1286
              V    ++ E  P   T++          ++  L DL ++   +S+  L+          
Sbjct: 19954 RVSAENENGEGTPSEITVVARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPIKGKPAPS 20013

Query: 1287  --WTPLNSSTIIGYRITVVAAGEGIP-IFEDFVDSSVGYYTVTGLEPGIDYDISVITLIN 1343
               W           R++V ++      I  D   S  G YT+T        + ++   + 
Sbjct: 20014 VSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKEGTISIKVV 20073

Query: 1344  GGESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAPPP---SIDLTNFLVRYSPVKNEE 1400
             G    PT             ++F  +  + M + WAPP      ++TN+++      N +
Sbjct: 20074 GKPGIPT-----------GPIKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDSVNNK 20122

Query: 1401  DVAELSISPSDNAVVLTNLLPGTEYVVSVSS-----VYEQHESTPLRGRQKTGL-DSPTG 1454
              V   S +       +T L  G EY   VS+     V E  +S P+  R    + D+P  
Sbjct: 20123 WVTCAS-AVQKTTFRVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVPDAPPP 20181

Query: 1455  IDFSDITANSFTVHWIAPRAT----ITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLT 1510
              +  D+  +S ++ W  P+ T    ITGY +     +     R ++ P       +T LT
Sbjct: 20182 PNIVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTPIRMRDFKVTGLT 20241

Query: 1511  PGTEYVVSIVALN----GREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAV-- 1564
              G EY   ++A+N    G+   P          D P   EV+  T  S+ + W  P    
Sbjct: 20242 EGLEYEFRVMAINLAGVGKPSLPSEPVVALDPIDPPGKPEVINITRNSVTLIWTEPKYDG 20301

Query: 1565  --TVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASS 1622
                +  Y +   +    S ++   V   +   T++ L  G  Y   + A    G   A S
Sbjct: 20302 GHKLTGYIVEKRDLPSKSWMKANHVNVPECAFTVTDLVEGGKYEFRIRAKNTAGAISAPS 20361

Query: 1623  KPI-SINYRTEIDKPSQMQVTDVQD------------NSISV--KWLPSSS-PVTGYRVT 1666
             +   +I  + E + P+ +    ++D            N+IS+  K LP SS    G  + 
Sbjct: 20362 ESTETIICKDEYEAPTIVLDPTIKDGLTIKAGDTIVLNAISILGKPLPKSSWSKAGKDIR 20421

Query: 1667  TTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRP 1726
                   P      T+ P  + +TI+          ++ A NP G     V+  V ++  P
Sbjct: 20422 ------PSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFGTKVEHVKVTVLDVPGP 20475

Query: 1727  KG-LAFTDVDVDSIKIAWESP---QGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQG 1782
              G +  ++V  +   + W  P    G   +  +        +     + D +        
Sbjct: 20476 PGPVEISNVSAEKATLTWTPPLEDGGSPIKSYILEKRETSRLLWTVVSEDIQSCRHVATK 20535

Query: 1783  LRPGSEYTVSVVALH-----DDMESQPLIGTQSTAIPAPTDL-KFTQVTPTSLSAQWTPP 1836
             L  G+EY   V A++     + ++S+P+        P P +  + + VT  + +  W  P
Sbjct: 20536 LIQGNEYIFRVSAVNHYGKGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSWKRP 20595

Query: 1837  ----NVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTS 1892
                   ++TGY V    K+    ++ I          V+GL   + YE  V A       
Sbjct: 20596 VDDGGSEITGYHVERREKKSLRWVRAIKTPVSDLRCKVTGLQEGSTYEFRVSAENRAGIG 20655

Query: 1893  RPAQGVVTTLEN-----VSPPRRARVTDATETTITISWRTKTE----TITGFQVDAVPAN 1943
              P++   + L         PP    VTD T+ + +++W          ITG+ V+     
Sbjct: 20656 PPSEASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLAWGKPHYDGGLEITGYVVEHQKVG 20715

Query: 1944  GQTPIQRTIKPDVR--SYTITGLQPGTDYKIYLYTLNDNARSSPVVI 1988
              +  I+ T    +R   + +  LQ    Y   +  +ND     P VI
Sbjct: 20716 DEAWIKDTTGTALRITQFVVPDLQTKEKYNFRISAINDAGVGEPAVI 20762



 Score =  136 bits (342), Expect = 3e-31
 Identities = 287/1435 (20%), Positives = 516/1435 (35%), Gaps = 196/1435 (13%)

Query: 794   SEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ----APITGYRIVYSPSV 849
             +  G +S  +       P  P    ++++     ++ W  P     + IT Y +    + 
Sbjct: 19372 NSSGSKSATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYIVDKRETS 19431

Query: 850   EGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPS 909
               +  +++      S ++  L  G +Y   I A  +     PV  +      P     P 
Sbjct: 19432 RPNWAQVSATVPITSCSVEKLIEGHEYQFRICAENKYGVGDPVFTEPAIAKNPYDP--PG 19489

Query: 910   PRDLQFVE-VTDVKVTIMWTPPE----SAVTGYRVDVIPVNLPG-EHGQRLPISRNTFAE 963
               D   +  +T   +T+ W PP     S +TGY ++             R PI   T  +
Sbjct: 19490 RCDPPVISNITKDHMTVSWKPPADDGGSPITGYLLEKRETQAVNWTKVNRKPIIERTL-K 19548

Query: 964   VTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKL-------DAPTNLQFVNETDSTVLVR 1016
              TGL  G  Y F+V A++     KP  A +             P   +  + T S+V + 
Sbjct: 19549 ATGLQEGTEYEFRVTAINKAGPGKPSDASKAAYARDPQYPPGPPAFPKVYDTTRSSVSLS 19608

Query: 1017  WTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSVSK--YPLRNLQPASEYTVSLVAIK 1070
             W  P     + I GY + V         + N+  ++ K  + +  L   ++Y   + A+ 
Sbjct: 19609 WGKPAYDGGSPIIGYLVEVKRADSDNWVRCNLPQNLQKTRFEVTGLMEDTQYQFRVYAVN 19668

Query: 1071  GNQESPKATGVFTTLQPGSSIPP---YNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEA 1127
                 S  +            IPP    + ++ +T I+       R G  + +     G  
Sbjct: 19669 KIGYSDPSDVPDKHYPKDILIPPEGELDADLRKTLIL-------RAGVTMRLYVPVKGRP 19721

Query: 1128  PREVTSDSGSIVVS---GLT------------------PGVEYVYTIQVLRDGQERDAPI 1166
             P ++T    ++ +    GL                      +Y+ T++      +++  I
Sbjct: 19722 PPKITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKYILTLE--NSCGKKEYTI 19779

Query: 1167  VNKVVTPLSPPTNLHL-EANPDTGVLTVSWERSTTPDITG----YRITTTPTNGQQGNSL 1221
             V KV+    PP N+ + E + D+  +T  WE    P I G            + ++ +  
Sbjct: 19780 VVKVLDTPGPPVNVTVKEISKDSAYVT--WE---PPIIDGGSPIINYVVQKRDAERKSWS 19834

Query: 1222  EEVVHADQSSCTFDNLSPGLEYNVSVYTVKD--------DKESVPISDTIIPEVPQLTDL 1273
                    ++S    NL  G  Y   V+   +         +++V  S T  P V    DL
Sbjct: 19835 TVTTECSKTSFRVANLEEGKSYFFRVFAENEYGIGDPGETRDAVKASQTPGPVV----DL 19890

Query: 1274  SFVDITDSSIGLRWTPLNS---STIIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEP 1330
                 ++ SS  + W   +S   S IIGY +  +        ++  + S    Y+   L  
Sbjct: 19891 KVRSVSKSSCSIGWKKPHSDGGSRIIGYVVDFLTEENK---WQRVMKSLSLQYSAKDLTE 19947

Query: 1331  GIDYDISVITLINGGESAPTTLT---QQTAVPPPTDLRFTNIGPDT-------------M 1374
             G +Y   V      GE  P+ +T   +   V P  DL+     PD              +
Sbjct: 19948 GKEYTFRVSAENENGEGTPSEITVVARDDVVAPDLDLKGL---PDLCYLAKENSNFRLKI 20004

Query: 1375  RVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLL-------PGTEYVV 1427
              +   P PS+         S  K E+ +A  +    +++ V T L+          +Y +
Sbjct: 20005 PIKGKPAPSV---------SWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTI 20055

Query: 1428  SVSSVYEQHEST-PLRGRQKTGLDSPTG-IDFSDITANSFTVHWIAPR----ATITGYRI 1481
             ++ +V    E T  ++   K G+  PTG I F ++TA + T+ W  P+    + IT Y I
Sbjct: 20056 TLKNVAGTKEGTISIKVVGKPGI--PTGPIKFDEVTAEAMTLKWAPPKDDGGSEITNY-I 20112

Query: 1482  RHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN------GREESPLLIGQQ 1535
                 +  + +         + +  +T L  G EY   + A N      G +  P++    
Sbjct: 20113 LEKRDSVNNKWVTCASAVQKTTFRVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHP 20172

Query: 1536  STVSDVPRDLEVVAATPTSLLISWDAPAVT----VRYYRITYGETGGNSPVQEFTVPGSK 1591
               V D P    +V     S+ ++W  P  T    +  Y + + E       +    P   
Sbjct: 20173 FDVPDAPPPPNIVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTPIRM 20232

Query: 1592  STATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISV 1651
                 ++GL  G++Y   V A+   G    S     +     ID P + +V ++  NS+++
Sbjct: 20233 RDFKVTGLTEGLEYEFRVMAINLAGVGKPSLPSEPVVALDPIDPPGKPEVINITRNSVTL 20292

Query: 1652  KWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQN 1707
              W          +TGY V           K       +   T+  L    +Y   + A+N
Sbjct: 20293 IWTEPKYDGGHKLTGYIVEKRDLPSKSWMKANHVNVPECAFTVTDLVEGGKYEFRIRAKN 20352

Query: 1708  PSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQV----------------S 1751
              +G      ++  T I + +  A T V   +IK       G                  S
Sbjct: 20353 TAGAISAPSESTETIICKDEYEAPTIVLDPTIKDGLTIKAGDTIVLNAISILGKPLPKSS 20412

Query: 1752  RYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQST 1811
               +         I ++   P     T +    +   EYT++             +     
Sbjct: 20413 WSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFGTKVEHVKVTVLDV 20472

Query: 1812  AIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVR--VTPKEKTGPMKEINLAPDSSSV- 1868
               P P  ++ + V+    +  WTPP ++  G  ++  +  K +T  +    ++ D  S  
Sbjct: 20473 PGP-PGPVEISNVSAEKATLTWTPP-LEDGGSPIKSYILEKRETSRLLWTVVSEDIQSCR 20530

Query: 1869  -VVSGLMVATKYEVSVYALKDTLTSRPAQG----VVTTLENVSPPRRARVTDATETTITI 1923
              V + L+   +Y   V A+       P Q     +V       PP +  V++ T+ T T+
Sbjct: 20531 HVATKLIQGNEYIFRVSAVNHYGKGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTATV 20590

Query: 1924  SWRTKTE----TITGFQVDAVPANGQTPIQRTIKPDVRSY--TITGLQPGTDYKIYLYTL 1977
             SW+   +     ITG+ V+         + R IK  V      +TGLQ G+ Y+  +   
Sbjct: 20591 SWKRPVDDGGSEITGYHVERREKKSLRWV-RAIKTPVSDLRCKVTGLQEGSTYEFRVSAE 20649

Query: 1978  N-------DNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYII 2026
             N         A  S ++ DA+     PSN     TT  S  ++W  P       ITGY++
Sbjct: 20650 NRAGIGPPSEASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLAWGKPHYDGGLEITGYVV 20709

Query: 2027  KYEKPGSPPREVVPRPRPG----VTEATITGLEPGTEYTIYVIALKNNQKSEPLI 2077
             +++K G    E   +   G    +T+  +  L+   +Y   + A+ +    EP +
Sbjct: 20710 EHQKVGD---EAWIKDTTGTALRITQFVVPDLQTKEKYNFRISAINDAGVGEPAV 20761



 Score =  133 bits (335), Expect = 2e-30
 Identities = 325/1621 (20%), Positives = 584/1621 (36%), Gaps = 231/1621 (14%)

Query: 628   IQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISI 684
             + W  P     S I+ Y+L  R   +V   K    P    +    GL+ G  YE ++ +I
Sbjct: 19506 VSWKPPADDGGSPITGYLLEKRETQAVNWTKVNRKPIIERTLKATGLQEGTEYEFRVTAI 19565

Query: 685   QQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSW---- 740
              + G  + +              S         + P       V + T SS  +SW    
Sbjct: 19566 NKAGPGKPSD------------ASKAAYARDPQYPPGPPAFPKVYDTTRSSVSLSWGKPA 19613

Query: 741   VSASDTVSGFRVEYELSEEGDEPQYLDLPSTA--TSVNIPDLLPGRKYIVNVYQISEDGE 798
                   + G+ VE + ++  D     +LP     T   +  L+   +Y   VY +++ G 
Sbjct: 19614 YDGGSPIIGYLVEVKRADS-DNWVRCNLPQNLQKTRFEVTGLMEDTQYQFRVYAVNKIGY 19672

Query: 799   QSLILSTSQTTAPDA--------PPDPTVDQVDDTSIVVRWS---RPQAPITGYRIVYSP 847
                   +  +  PD         PP+  +D     ++++R     R   P+ G      P
Sbjct: 19673 ------SDPSDVPDKHYPKDILIPPEGELDADLRKTLILRAGVTMRLYVPVKGRP---PP 19723

Query: 848   SVEGSSTELNLPETAN-SVTLSDLQPGVQ-----------YNITIYAVEENQESTPVVIQ 895
              +  S   +NL +     +  +D    ++           Y +T+      +E T VV  
Sbjct: 19724 KITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKYILTLENSCGKKEYTIVVKV 19783

Query: 896   QETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPGEHG 951
              +T G P + TV         E++     + W PP     S +  Y V            
Sbjct: 19784 LDTPGPPVNVTVK--------EISKDSAYVTWEPPIIDGGSPIINYVVQKRDAERKSWST 19835

Query: 952   QRLPISRNTFAEVTGLSPGVTYYFKVFAVSH---GRESKPLTAQQTTKLDAPT-NLQFVN 1007
                  S+ +F  V  L  G +Y+F+VFA +    G   +   A + ++   P  +L+  +
Sbjct: 19836 VTTECSKTSF-RVANLEEGKSYFFRVFAENEYGIGDPGETRDAVKASQTPGPVVDLKVRS 19894

Query: 1008  ETDSTVLVRWTPPRA----QITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYT 1063
              + S+  + W  P +    +I GY +   LT   + ++     S+ +Y  ++L    EYT
Sbjct: 19895 VSKSSCSIGWKKPHSDGGSRIIGYVVDF-LTEENKWQRVMKSLSL-QYSAKDLTEGKEYT 19952

Query: 1064  VSLVAIKGNQE-SPKATGVFT---TLQPG---SSIPPYNTEVTETT-----IVITWTPAP 1111
               + A   N E +P    V      + P      +P       E +     I I   PAP
Sbjct: 19953 FRVSAENENGEGTPSEITVVARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPIKGKPAP 20012

Query: 1112  RIGFKLGVRP-SQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKV 1170
              + +K G  P +       E ++ + +++V          YTI +      ++  I  KV
Sbjct: 20013 SVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKEGTISIKV 20072

Query: 1171  VTPLSPPTNLHLEANPDTGVLTVSW---ERSTTPDITGYRITTTPTNGQQGNSLEEVVHA 1227
             V     PT            +T+ W   +     +IT Y +    +   +  +    V  
Sbjct: 20073 VGKPGIPTGPIKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDSVNNKWVTCASAVQK 20132

Query: 1228  DQSSCTFDNLSPGLEYNVSV-----YTVKDDKESVPI---SDTIIPEVPQLTDLSFVDIT 1279
                  T   L  G+EY   V     Y V +  +S PI       +P+ P   ++  VD+ 
Sbjct: 20133 TTFRVT--RLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVPDAPPPPNI--VDVR 20188

Query: 1280  DSSIGLRWTP---LNSSTIIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDI 1336
               S+ L WT       S I GY +        +    +     +  + VTGL  G++Y+ 
Sbjct: 20189 HDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTPIRMRDFKVTGLTEGLEYEF 20248

Query: 1337  SVITLINGGESAPTTLTQQTA----VPPPTDLRFTNIGPDTMRVTWAPPP---SIDLTNF 1389
              V+ +   G   P+  ++       + PP      NI  +++ + W  P       LT +
Sbjct: 20249 RVMAINLAGVGKPSLPSEPVVALDPIDPPGKPEVINITRNSVTLIWTEPKYDGGHKLTGY 20308

Query: 1390  LVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVV---------SVSSVYEQHESTP 1440
             +V    + ++  +    ++  + A  +T+L+ G +Y           ++S+  E  E+  
Sbjct: 20309 IVEKRDLPSKSWMKANHVNVPECAFTVTDLVEGGKYEFRIRAKNTAGAISAPSESTETII 20368

Query: 1441  LRGRQK--TGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVP 1498
              +   +  T +  PT  D   I A    V       +I G  +   P+    +  +D  P
Sbjct: 20369 CKDEYEAPTIVLDPTIKDGLTIKAGDTIV---LNAISILGKPL---PKSSWSKAGKDIRP 20422

Query: 1499  HSRNSITLTNLTP-----------GTEYVVSIVALNGREESPLLIGQQSTVSDVPRD--- 1544
                  IT T  +              EY ++     G +   + +    TV DVP     
Sbjct: 20423 SDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFGTKVEHVKV----TVLDVPGPPGP 20478

Query: 1545  LEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATI-------- 1596
             +E+   +     ++W  P            E GG SP++ + +   +++  +        
Sbjct: 20479 VEISNVSAEKATLTWTPPL-----------EDGG-SPIKSYILEKRETSRLLWTVVSEDI 20526

Query: 1597  -------SGLKPGVDYTITVYAVT--GRGDSPASSKPISINYRT-EIDKPSQMQVTDVQD 1646
                    + L  G +Y   V AV   G+G+ P  S+P+ +  R      P + +V++V  
Sbjct: 20527 QSCRHVATKLIQGNEYIFRVSAVNHYGKGE-PVQSEPVKMVDRFGPPGPPEKPEVSNVTK 20585

Query: 1647  NSISVKWL----PSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVS 1702
             N+ +V W        S +TGY V    K      +            + GLQ    Y   
Sbjct: 20586 NTATVSWKRPVDDGGSEITGYHVERREKKSLRWVRAIKTPVSDLRCKVTGLQEGSTYEFR 20645

Query: 1703  VYAQNPSGESQP-------LVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQG----QVS 1751
             V A+N +G   P       L++ A      P     TD    S  +AW  P      +++
Sbjct: 20646 VSAENRAGIGPPSEASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLAWGKPHYDGGLEIT 20705

Query: 1752  RYRVTYSSPEDGIHELFPAPDGEEDTA-ELQGLRPGSEYTVSVVALHDDMESQPLIGTQS 1810
              Y V +    D              T   +  L+   +Y   + A++D    +P +    
Sbjct: 20706 GYVVEHQKVGDEAWIKDTTGTALRITQFVVPDLQTKEKYNFRISAINDAGVGEPAV---- 20761

Query: 1811  TAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDS----- 1865
               IP    ++        L A+     V   G  +R+    K  P  E+    D+     
Sbjct: 20762 --IPDVEIVEREMAPDFELDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKN 20819

Query: 1866  -------SSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTT--LENVSPPRRARVTDA 1916
                     S  +  +    +Y+   + +     +    G V    L+   P    R TD 
Sbjct: 20820 RANIENTESFTLLIIPECNRYDTGKFVMTIENPAGKKSGFVNVRVLDTPGPVLNLRPTDI 20879

Query: 1917  TETTITISWRTKT----ETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKI 1972
             T+ ++T+ W          IT + V+   A  ++    T K    +Y +TGL  G +Y  
Sbjct: 20880 TKDSVTLHWDLPLIDGGSRITNYIVEKREATRKSYSTATTKCHKCTYKVTGLSEGCEYFF 20939

Query: 1973  YLYTLNDNARSSPVV----IDASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGY 2024
              +   N+     P      + AS A   P +L  +  T +++ ++W  P+    ++ITGY
Sbjct: 20940 RVMAENEYGIGEPTETTEPVKASEAPSPPDSLNIMDITKSTVSLAWPKPKHDGGSKITGY 20999

Query: 2025  IIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQ 2084
             +I+ ++ GS     +   +    E  +  L  G EYT  V+A+ +  +S P   R   V+
Sbjct: 21000 VIEAQRKGSDQWTHITTVKG--LECVVRNLTEGEEYTFQVMAVNSAGRSAPRESRPVIVK 21057

Query: 2085  K 2085
             +
Sbjct: 21058 E 21058



 Score =  128 bits (322), Expect = 6e-29
 Identities = 343/1604 (21%), Positives = 574/1604 (35%), Gaps = 260/1604 (16%)

Query: 611   PVEVFITETPSQPNSHPIQWNAPQ---PSHISKYILRWRPKNSVGRWKEATIPGHLNS-- 665
             P ++ I +  S  +S  + W+ P     S ++ Y++  R +     W   +  G + +  
Sbjct: 27170 PAKIRIAD--STKSSITLGWSKPVYDGGSAVTGYVVEIR-QGEEEEWTTVSTKGEVRTTE 27226

Query: 666   YTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATS 725
             Y +  LKPGV Y  ++ ++   G  E    +    +                 S +    
Sbjct: 27227 YVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQAKDILEAPEIDLDVALRTSVIAKAG 27286

Query: 726   ESVTEITASSF----VVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLL 781
             E V  +          V+W      + G    Y + E  D    L +P    +       
Sbjct: 27287 EDVQVLIPFKGRPPPTVTWRKDEKNL-GSDARYSI-ENTDSSSLLTIPQVTRNDT----- 27339

Query: 782   PGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ----AP 837
                KYI+ +     + + S + S      P A     V  V   ++ + W  P     +P
Sbjct: 27340 --GKYILTIENGVGEPKSSTV-SVKVLDTPAACQKLQVKHVSRGTVTLLWDPPLIDGGSP 27396

Query: 838   ITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQE 897
             I  Y I    + + + + ++   ++ S  L DL     +   + A  E     P     E
Sbjct: 27397 IINYVIEKRDATKRTWSVVSHKCSSTSFKLIDLSEKTPFFFRVLAENEIGIGEPC----E 27452

Query: 898   TTGTPRSDTVPSP-RDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPVNLPGEHG- 951
             TT   ++  VP+P RDL   + T   V + WT P+    S +T Y   V+     GE   
Sbjct: 27453 TTEPVKAAEVPAPIRDLSMKDSTKTSVILSWTKPDFDGGSVITEY---VVERKGKGEQTW 27509

Query: 952   QRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDS 1011
                 IS+    EV+ L       F+VFA +    S P+T    T  +    L    E D 
Sbjct: 27510 SHAGISKTCEIEVSQLKEQSVLEFRVFAKNEKGLSDPVTIGPITVKE----LIITPEVDL 27565

Query: 1012  TVLVRWTPPRAQIT---GYRLTVGLTRRGQPRQYNVGPSVS----KYPLRNLQ------P 1058
             + +     P AQ+T   G+ + + L  +G+P+     PS+S      PL+  +       
Sbjct: 27566 SDI-----PGAQVTVRIGHNVHLELPYKGKPK-----PSISWLKDGLPLKESEFVRFSKT 27615

Query: 1059  ASEYTVSLVAIKGNQESPKATGVFT-------------TLQPGSSI--PPYNTEVTETTI 1103
              ++ T+S+   K  +   K T +               TL P S    P    E+   ++
Sbjct: 27616 ENKITLSIKNAK-KEHGGKYTVILDNAVCRIAVPITVITLGPPSKPKGPIRFDEIKADSV 27674

Query: 1104  VITWTPAPRIGFKLGVRPSQGGEAP------REVTSDSGSIVVSG----------LTPGV 1147
             +++W      G         GGE        RE +  +  +V S           L    
Sbjct: 27675 ILSWDVPEDNG---------GGEITCYSIEKRETSQTNWKMVCSSVARTTFKVPNLVKDA 27725

Query: 1148  EYVYTIQVLRDGQERDAPIVNKVVTP-----LSPPTNLHLEANPDTGVLTVSWERSTTP- 1201
             EY + ++   +      P+V+ ++       +  P    +  N  +  ++++W+      
Sbjct: 27726 EYQFRVRA-ENRYGVSQPLVSSIIVAKHQFRIPGPPGKPVIYNVTSDGMSLTWDAPVYDG 27784

Query: 1202  --DITGYRITTTPTNG---QQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKES 1256
               ++TG+ +     N    Q+ N+    +   +   T   L  GL+Y   VY       S
Sbjct: 27785 GSEVTGFHVEKKERNSILWQKVNT--SPISGREYRAT--GLVEGLDYQFRVYAENSAGLS 27840

Query: 1257  VPISDT-----IIPEVPQLTDLSFVDITDSSIGLRWTPL---NSSTIIGYRITVVAAGEG 1308
              P   +     + P  P  T   ++D+T  +I L+W P      S I+GY I      E 
Sbjct: 27841 SPSDPSKFTLAVSPVDPPGTP-DYIDVTRETITLKWNPPLRDGGSKIVGYSIEKRQGNER 27899

Query: 1309  IPIFEDFVDSSVGYYTVTGLEPGIDYDISVI------TLINGGESAPTTLTQQTAVPPPT 1362
               +  +F D S   YTVTGL PG  Y+  +I      T+    +S+   +T+   VPP  
Sbjct: 27900 W-VRCNFTDVSECQYTVTGLSPGDRYEFRIIARNAVGTISPPSQSSGIIMTRDENVPP-- 27956

Query: 1363  DLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNE---EDVAELSISPSDNAVVLTNL 1419
                    GP+                 LV+  PV      +D  E+    +   + +T++
Sbjct: 27957 ---IVEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMN---MEITDV 28010

Query: 1420  LPGTEYVV--------SVSSVYEQHESTPLRGRQKTGLDSPTG-----IDFSDITANSFT 1466
             L  T   V         V +V  ++ S   +   K  +    G     I F++IT    T
Sbjct: 28011 LGSTSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQDTPGKVVGPIRFTNITGEKMT 28070

Query: 1467  VHWIAPR----ATITGYRI-RHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVA 1521
             + W AP     A IT Y I +      +    ED+      S T   L  G EY   + A
Sbjct: 28071 LWWDAPLNDGCAPITHYIIEKRETSRLAWALIEDKC--EAQSYTAIKLINGNEYQFRVSA 28128

Query: 1522  LN----GR--EESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGE 1575
             +N    GR  +  P++   Q TV D P   E    T  S+ ++W  P            E
Sbjct: 28129 VNKFGVGRPLDSDPVVAQIQYTVPDAPGIPEPSNITGNSITLTWARP------------E 28176

Query: 1576  TGGNSPVQEFTV-----------------PGSKSTATISGLKPGVDYTITVYAVTGRGDS 1618
             + G S +Q++ +                 P S++   ++GL  G +Y   V A    G  
Sbjct: 28177 SDGGSEIQQYILERREKKSTRWVKVISKRPISETRFKVTGLTEGNEYEFHVMAENAAGVG 28236

Query: 1619  PASSKPISINYRTEIDKPSQ---MQVTDVQDNSISVKW----LPSSSPVTGYRVTTTPKN 1671
             PAS     I  R  ++ P     ++VTD    ++S++W          + GY +     +
Sbjct: 28237 PASGISRLIKCREPVNPPGPPTVVKVTDTSKTTVSLEWSKPVFDGGMEIIGYIIEMCKAD 28296

Query: 1672  GPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTA-VTNIDRPKGLA 1730
                  K       +T  T+  LQ   EY   V A N +G+      T  +  +DR   L 
Sbjct: 28297 LGDWHKVNAEACVKTRYTVTDLQAGEEYKFRVSAINGAGKGDSCEVTGTIKAVDR---LT 28353

Query: 1731  FTDVDVDS-IKIAWESPQGQVSRYRVTY----------SSPEDGIH---ELFPAPDGEED 1776
               ++D+D+  K       G   R  + Y          S P+  +    ++         
Sbjct: 28354 APELDIDANFKQTHVVRAGASIRLFIAYQGRPTPTAVWSKPDSNLSLRADIHTTDSFSTL 28413

Query: 1777  TAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPP 1836
             T E        +YT++V            +    T  P P  + F  VT  S +  W  P
Sbjct: 28414 TVENCNRNDAGKYTLTVENNSGSKSITFTVKVLDTPGP-PGPITFKDVTRGSATLMWDAP 28472

Query: 1837  NVQLTGYRVRVTPKEKTGPMKE----INLAPDSSSVVVSGLMVATKYEVSVYALKDTLTS 1892
              +   G R+     EK    +     I+         V+ L     Y   V A+ +    
Sbjct: 28473 LLD-GGARIHHYVVEKREASRRSWQVISEKCTRQIFKVNDLAEGVPYYFRVSAVNEYGVG 28531

Query: 1893  RPAQ--GVVTTLENVSPPRRARVTDATETTITISW----RTKTETITGFQVDAVPANGQT 1946
              P +    +   E  +PPRR  V D ++++  ++W          ITG+ ++        
Sbjct: 28532 EPYEMPEPIVATEQPAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSDF 28591

Query: 1947  PIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATT 2006
              ++      + ++T+  L   T+Y+  +   ND   S P    +S  I  P         
Sbjct: 28592 WVEAGHTKQL-TFTVERLVEKTEYEFRVKAKNDAGYSEPREAFSSVIIKEPQ------IE 28644

Query: 2007  PNSLLVSWQPPRARITGYIIKYEKPGSPPREVVP---RPRPGVT 2047
             P + L         IT  +I   K GSP    VP   RP P VT
Sbjct: 28645 PTADLTG-------ITNQLITC-KAGSPFTIDVPISGRPAPKVT 28680



 Score =  124 bits (311), Expect = 1e-27
 Identities = 291/1338 (21%), Positives = 513/1338 (38%), Gaps = 174/1338 (13%)

Query: 780   LLPGRKYI-----VNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRP 834
             ++ G +YI     VN Y I E  E   +++ +    P  P  P V ++   S+ V WSRP
Sbjct: 27030 IIKGNEYIFRVRAVNKYGIGEPLESDSVVAKNAFVTPGPPGIPEVTKITKNSMTVVWSRP 27089

Query: 835   QA----PITGYRIVYSPSVEGSSTEL---NLPETANSVTLSDLQPGVQYNI-TIYAVEEN 886
              A     I+GY +           ++    + +T   VT        QY +  + A  + 
Sbjct: 27090 IADGGSDISGYFLEKRDKKSLGWFKVLKETIRDTRQKVTGLTENSDYQYRVCAVNAAGQG 27149

Query: 887   QESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVI 942
               S P    +        D    P  ++  + T   +T+ W+ P     SAVTGY V++ 
Sbjct: 27150 PFSEP---SEFYKAADPIDPPGPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVVEI- 27205

Query: 943   PVNLPGEHGQRLPIS-----RNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTK- 996
                  GE  +   +S     R T   V+ L PGV YYF+V AV+   + +P+   +  + 
Sbjct: 27206 ---RQGEEEEWTTVSTKGEVRTTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQA 27262

Query: 997   ---LDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQP--------RQYNVG 1045
                L+AP       E D  V +R T   A+  G  + V +  +G+P         + N+G
Sbjct: 27263 KDILEAP-------EIDLDVALR-TSVIAK-AGEDVQVLIPFKGRPPPTVTWRKDEKNLG 27313

Query: 1046  PSVSKYPLRNLQPASEYTVS----------LVAIKGNQESPKATGVFTTL--QPGSSIPP 1093
              S ++Y + N   +S  T+           ++ I+     PK++ V   +   P +    
Sbjct: 27314 -SDARYSIENTDSSSLLTIPQVTRNDTGKYILTIENGVGEPKSSTVSVKVLDTPAACQKL 27372

Query: 1094  YNTEVTETTIVITWTP------APRIGFKLGVRPS---QGGEAPREVTSDSGSIV-VSGL 1143
                 V+  T+ + W P      +P I + +  R +          + +S S  ++ +S  
Sbjct: 27373 QVKHVSRGTVTLLWDPPLIDGGSPIINYVIEKRDATKRTWSVVSHKCSSTSFKLIDLSEK 27432

Query: 1144  TPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDI 1203
             TP    V     +  G+  +     K     +P  +L ++ +  T V+ +SW   T PD 
Sbjct: 27433 TPFFFRVLAENEIGIGEPCETTEPVKAAEVPAPIRDLSMKDSTKTSVI-LSW---TKPDF 27488

Query: 1204  TGYRITTTPTNGQQGNSLEEVVHADQS-SCTFD----NLSPGLEYNVSVYTVKDDKESVP 1258
              G  + T     ++G   +   HA  S +C  +         LE+ V     K   + V 
Sbjct: 27489 DGGSVITEYVVERKGKGEQTWSHAGISKTCEIEVSQLKEQSVLEFRVFAKNEKGLSDPVT 27548

Query: 1259  ISDTIIPEVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGY----RITVVAAGEGIPIFE- 1313
             I    + E+    ++   DI  + + +R    N    + Y    + ++    +G+P+ E 
Sbjct: 27549 IGPITVKELIITPEVDLSDIPGAQVTVR-IGHNVHLELPYKGKPKPSISWLKDGLPLKES 27607

Query: 1314  DFVDSSVGYYTVT------GLEPGIDYDISVITLINGGESAPTTLTQQTAVPPPTDLRFT 1367
             +FV  S     +T        E G  Y + +   +       T +T      P   +RF 
Sbjct: 27608 EFVRFSKTENKITLSIKNAKKEHGGKYTVILDNAVCRIAVPITVITLGPPSKPKGPIRFD 27667

Query: 1368  NIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSI---SPSDNAVVLTNLLPGTE 1424
              I  D++ ++W  P   +    +  YS  K E       +   S +     + NL+   E
Sbjct: 27668 EIKADSVILSWDVPED-NGGGEITCYSIEKRETSQTNWKMVCSSVARTTFKVPNLVKDAE 27726

Query: 1425  YVVSVSSVYEQHESTPL-----RGRQKTGLDSPTGID-FSDITANSFTVHWIAP----RA 1474
             Y   V +      S PL       + +  +  P G     ++T++  ++ W AP     +
Sbjct: 27727 YQFRVRAENRYGVSQPLVSSIIVAKHQFRIPGPPGKPVIYNVTSDGMSLTWDAPVYDGGS 27786

Query: 1475  TITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQ 1534
              +TG+ +     +     + +  P S      T L  G +Y   + A N    S      
Sbjct: 27787 EVTGFHVEKKERNSILWQKVNTSPISGREYRATGLVEGLDYQFRVYAENSAGLSSPSDPS 27846

Query: 1535  QSTVS----DVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYG---ETGGNSPVQEFTV 1587
             + T++    D P   + +  T  ++ + W+ P        + Y      G    V+    
Sbjct: 27847 KFTLAVSPVDPPGTPDYIDVTRETITLKWNPPLRDGGSKIVGYSIEKRQGNERWVRCNFT 27906

Query: 1588  PGSKSTATISGLKPGVDYTITVYAVTGRGD-SPASSKPISINYRTEIDKPSQMQVTDVQD 1646
               S+   T++GL PG  Y   + A    G  SP S     I  R E   P      +  D
Sbjct: 27907 DVSECQYTVTGLSPGDRYEFRIIARNAVGTISPPSQSSGIIMTRDENVPPIVEFGPEYFD 27966

Query: 1647  -------NSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTK----TAGPDQTEMTIEGLQP 1695
                     S+ +K L    PV   RVT   K+G    K      T     T + +     
Sbjct: 27967 GLIIKSGESLRIKALVQGRPVP--RVTWF-KDGVEIEKRMNMEITDVLGSTSLFVRDATR 28023

Query: 1696  TVEYVVSVYAQNPSGESQPLVQTAVTNIDRP----KGLAFTDVDVDSIKIAWESPQGQ-- 1749
                 V +V A+N SG ++  ++  V   D P      + FT++  + + + W++P     
Sbjct: 28024 DHRGVYTVEAKNASGSAKAEIKVKVQ--DTPGKVVGPIRFTNITGEKMTLWWDAPLNDGC 28081

Query: 1750  --VSRYRVTYSSPEDGIHELFPAPDGEEDTAELQG-----LRPGSEYTVSVVALHD---- 1798
               ++ Y +           L       ED  E Q      L  G+EY   V A++     
Sbjct: 28082 APITHYIIEKRETSRLAWALI------EDKCEAQSYTAIKLINGNEYQFRVSAVNKFGVG 28135

Query: 1799  -DMESQPLIGTQSTAIP-APTDLKFTQVTPTSLSAQWTPP----NVQLTGYRVRVTPKEK 1852
               ++S P++      +P AP   + + +T  S++  W  P      ++  Y +    K+ 
Sbjct: 28136 RPLDSDPVVAQIQYTVPDAPGIPEPSNITGNSITLTWARPESDGGSEIQQYILERREKKS 28195

Query: 1853  TGPMKEINLAPDSSS-VVVSGLMVATKYEVSVYALKDTLTSRPAQGV---VTTLENVS-- 1906
             T  +K I+  P S +   V+GL    +YE  V A ++     PA G+   +   E V+  
Sbjct: 28196 TRWVKVISKRPISETRFKVTGLTEGNEYEFHVMA-ENAAGVGPASGISRLIKCREPVNPP 28254

Query: 1907  -PPRRARVTDATETTITISWRTKT----ETITGFQVDAVPANGQTPIQRTIKPDVRS-YT 1960
              PP   +VTD ++TT+++ W          I G+ ++   A+     +   +  V++ YT
Sbjct: 28255 GPPTVVKVTDTSKTTVSLEWSKPVFDGGMEIIGYIIEMCKADLGDWHKVNAEACVKTRYT 28314

Query: 1961  ITGLQPGTDYKIYLYTLN 1978
             +T LQ G +YK  +  +N
Sbjct: 28315 VTDLQAGEEYKFRVSAIN 28332



 Score =  123 bits (309), Expect = 2e-27
 Identities = 310/1432 (21%), Positives = 508/1432 (35%), Gaps = 230/1432 (16%)

Query: 814   PPDPT-VDQVDDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTLS 868
             PP P  +  V      + W+ P     +PI  Y +    +     T ++    +     +
Sbjct: 20475 PPGPVEISNVSAEKATLTWTPPLEDGGSPIKSYILEKRETSRLLWTVVSEDIQSCRHVAT 20534

Query: 869   DLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVE-VTDVKVTIMW 927
              L  G +Y   + AV    +  PV  Q E          P P +   V  VT    T+ W
Sbjct: 20535 KLIQGNEYIFRVSAVNHYGKGEPV--QSEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSW 20592

Query: 928   TPPE----SAVTGYRVDVIPV-NLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSH 982
               P     S +TGY V+     +L      + P+S +   +VTGL  G TY F+V A + 
Sbjct: 20593 KRPVDDGGSEITGYHVERREKKSLRWVRAIKTPVS-DLRCKVTGLQEGSTYEFRVSAENR 20651

Query: 983   GRESKPLTAQQTTKL-DA------PTNLQFVNETDSTVLVRWTPPR----AQITGYRLTV 1031
                  P  A  +  + DA      P+N    + T  +  + W  P      +ITGY +  
Sbjct: 20652 AGIGPPSEASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLAWGKPHYDGGLEITGYVVEH 20711

Query: 1032  GLTRRGQPRQYNVGPS--VSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGS 1089
                      +   G +  ++++ + +LQ   +Y   + AI        A      +    
Sbjct: 20712 QKVGDEAWIKDTTGTALRITQFVVPDLQTKEKYNFRISAINDAGVGEPAVIPDVEIVERE 20771

Query: 1090  SIPPY--NTEVTETTIVITWTPAPRIGFKLGVR-PSQGGEAPREVTSDSGSIVVSG---- 1142
               P +  + E+  T +V       R G  + +  P +G  AP EVT    +I +      
Sbjct: 20772 MAPDFELDAELRRTLVV-------RAGLSIRIFVPIKGRPAP-EVTWTKDNINLKNRANI 20823

Query: 1143  ---------LTPGVEYVYT---IQVLRDGQERDAPIVN-KVVTPLSPPTNLH-LEANPDT 1188
                      + P      T   +  + +   + +  VN +V+    P  NL   +   D+
Sbjct: 20824 ENTESFTLLIIPECNRYDTGKFVMTIENPAGKKSGFVNVRVLDTPGPVLNLRPTDITKDS 20883

Query: 1189  GVLTVSWERSTTPD---ITGYRITTTPTNGQQGNSLEEVVHADQSSCTFD--NLSPGLEY 1243
               +T+ W+         IT Y +       +  ++     H     CT+    LS G EY
Sbjct: 20884 --VTLHWDLPLIDGGSRITNYIVEKREATRKSYSTATTKCH----KCTYKVTGLSEGCEY 20937

Query: 1244  NVSV-----YTVKDDKESV-PISDTIIPEVPQLTDLSFVDITDSSIGLRWTPLN---SST 1294
                V     Y + +  E+  P+  +  P  P    L+ +DIT S++ L W        S 
Sbjct: 20938 FFRVMAENEYGIGEPTETTEPVKASEAPSPPD--SLNIMDITKSTVSLAWPKPKHDGGSK 20995

Query: 1295  IIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLE-------PGIDYDISVITLINGGES 1347
             I GY I     G          D      TV GLE        G +Y   V+ + + G S
Sbjct: 20996 ITGYVIEAQRKGS---------DQWTHITTVKGLECVVRNLTEGEEYTFQVMAVNSAGRS 21046

Query: 1348  APT----TLTQQTAVPPPTDLR-------FTNIGPDT---MRVTWAPPPSIDLTNFLVRY 1393
             AP      + ++  + P  DLR           G +    + V   P P++         
Sbjct: 21047 APRESRPVIVKEQTMLPELDLRGIYQKLVIAKAGDNIKVEIPVLGRPKPTVTW------- 21099

Query: 1394  SPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGL---- 1449
                K  + + + +   +      + +L   E V S S  Y      PL  R   G     
Sbjct: 21100 ---KKGDQILKQTQRVNFETTATSTILNINECVRSDSGPY------PLTARNIVGEVGDV 21150

Query: 1450  ---------DSPTG-IDFSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPRED 1495
                        PTG I F +++++  T  W  P       I+ Y +       S    E 
Sbjct: 21151 ITIQVHDIPGPPTGPIKFDEVSSDFVTFSWDPPENDGGVPISNYVVEMRQTD-STTWVEL 21209

Query: 1496  RVPHSRNSITLTNLTPGTEYVVSIVALN------GREESPLLIGQQSTVSDVPRDLEVVA 1549
                  R +   T LT G EY   + A N      G   + ++      V   P   +V A
Sbjct: 21210 ATTVIRTTYKATRLTTGLEYQFRVKAQNRYGVGPGITSACIVANYPFKVPGPPGTPQVTA 21269

Query: 1550  ATPTSLLISWDAP----AVTVRYYRITYGETGGN--SPVQEFTVPGSKSTATISGLKPGV 1603
              T  S+ ISW  P       +  Y +   E  G     V +  VPG+   +  SGL  G+
Sbjct: 21270 VTKDSMTISWHEPLSDGGSPILGYHVERKERNGILWQTVSKALVPGNIFKS--SGLTDGI 21327

Query: 1604  DYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKW----LPSSSP 1659
              Y   V A    G S  S     +     ID P +    ++  +++++KW          
Sbjct: 21328 AYEFRVIAENMAGKSKPSKPSEPMLALDPIDPPGKPVPLNITRHTVTLKWAKPEYTGGFK 21387

Query: 1660  VTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQ-- 1717
             +T Y V           K   +   + E T+ GL     Y   V A+N +G   P  +  
Sbjct: 21388 ITSYIVEKRDLPNGRWLKANFSNILENEFTVSGLTEDAAYEFRVIAKNAAGAISPPSEPS 21447

Query: 1718  TAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDT 1777
              A+T  D        DV+   IK+  +     + +    +    D      P  +  +D 
Sbjct: 21448 DAITCRD--------DVEAPKIKVDVKFKDTVILKAGEAFRLEADVSGRPPPTMEWSKDG 21499

Query: 1778  AELQGL---------------------RPGSEYTVSVVALHDDMESQPLIGTQSTAIPAP 1816
              EL+G                      R    YT++  A +    ++ +   +    P P
Sbjct: 21500 KELEGTAKLEIKIADFSTNLVNKDSTRRDSGAYTLT--ATNPGGFAKHIFNVKVLDRPGP 21557

Query: 1817  TD--LKFTQVTPTSLSAQWTPP----NVQLTGYRVRVTPKEKTGPMKEINLAPD--SSSV 1868
              +  L  T+VT       W PP      ++  Y   +  K +T  +   N+A +   + +
Sbjct: 21558 PEGPLAVTEVTSEKCVLSWFPPLDDGGAKIDHY---IVQKRETSRLAWTNVASEVQVTKL 21614

Query: 1869  VVSGLMVATKY-----EVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITI 1923
              V+ L+   +Y      V+ Y + + L S P    V       PP+   VT  T+ ++ +
Sbjct: 21615 KVTKLLKGNEYIFRVMAVNKYGVGEPLESEPVL-AVNPYGPPDPPKNPEVTTITKDSMVV 21673

Query: 1924  SW----RTKTETITGFQVDAVPANGQTPIQRTIK--PDVRSYTITGLQPGTDYKIYLYTL 1977
              W          I  + V+     GQ  I+   K   D+R Y ++GL  G +Y+  +   
Sbjct: 21674 CWGHPDSDGGSEIINYIVERRDKAGQRWIKCNKKTLTDLR-YKVSGLTEGHEYEFRIMAE 21732

Query: 1978  NDNARSSP-------VVIDASTAIDAPSNLRFLATTPNSLLVSWQPP----RARITGYII 2026
             N    S+P          D       P N R L T+ +S+ ++W  P     + ITGY++
Sbjct: 21733 NAAGISAPSPTSPFYKACDTVFKPGPPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMV 21792

Query: 2027  KYEKPGSPPREVVPRPRP-GVTEATITGLEPGTEYTIYVIALKNNQKSEPLI 2077
             +   P     ++V  P     T  TITGL    EY I + A+ +    EP +
Sbjct: 21793 EIALPEEDEWQIVTPPAGLKATSYTITGLTENQEYKIRIYAMNSEGLGEPAL 21844



 Score =  123 bits (309), Expect = 2e-27
 Identities = 338/1634 (20%), Positives = 602/1634 (36%), Gaps = 228/1634 (13%)

Query: 613   EVFITETPSQPNSHP-----------IQWNAPQ---PSHISKYILRWRPKNSVGRWKEAT 658
             E ++   P  P   P           +QW  P     S I+ YI+  R     GRW +A+
Sbjct: 23513 ECYVARDPCDPPGTPEPIMVKRNEITLQWTKPVYDGGSMITGYIVEKRDLPD-GRWMKAS 23571

Query: 659   IPGHLNS-YTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTP 717
                 + + +T+ GL     YE ++I+    G         +  S ST      +T +   
Sbjct: 23572 FTNVIETQFTVSGLTEDQRYEFRVIAKNAAGA-------ISKPSDST----GPITAKDEV 23620

Query: 718   FSPLVATSESVTEITASSFVVSWVSASD-------TVSGFRVEYELSEEGD-EPQYLDLP 769
               P ++      +    +   ++   +D       T+   R + E+ E    E +  D  
Sbjct: 23621 ELPRISMDPKFRDTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFK 23680

Query: 770   STATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPT-VDQVDDTSIV 828
             +    V     + G +YI+    ++  G +S  ++      P  P  P  V  V      
Sbjct: 23681 ALLI-VKDAIRIDGGQYILRASNVA--GSKSFPVNVKVLDRPGPPEGPVQVTGVTSEKCS 23737

Query: 829   VRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITI---- 880
             + WS P     + I+ Y +    +   + T +      NS+ ++ L  G +Y   I    
Sbjct: 23738 LTWSPPLQDGGSDISHYVVEKRETSRLAWTVVASEVVTNSLKVTKLLEGNEYVFRIMAVN 23797

Query: 881   -YAVEENQESTPVVIQQETTGTPRSDTVPSP-RDLQFVEVTDVKVTIMWTPPES----AV 934
              Y V E  ES PV+++           +P P + L+   +    +T+ W  P+S     +
Sbjct: 23798 KYGVGEPLESAPVLMKNPFV-------LPGPPKSLEVTNIAKDSMTVCWNRPDSDGGSEI 23850

Query: 935   TGYRV---DVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTA 991
              GY V   D   +     + +R+   R     VTGL+    Y F+V A +     +P  A
Sbjct: 23851 IGYIVEKRDRSGIRWIKCNKRRITDLR---LRVTGLTEDHEYEFRVSAENAAGVGEPSPA 23907

Query: 992   -------QQTTKLDAPTNLQFVNETDSTVLVRWTPP----RAQITGYRLTVGLTRRGQPR 1040
                        K   PTN   V+ T +++ + W  P     ++I GY   V + +  +  
Sbjct: 23908 TVYYKACDPVFKPGPPTNAHIVDTTKNSITLAWGKPIYDGGSEILGY--VVEICKADEEE 23965

Query: 1041  QYNVGPS----VSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNT 1096
                V P     V+++ +  L    EY + + A+       +AT V  T++P   +     
Sbjct: 23966 WQIVTPQTGLRVTRFEISKLTEHQEYKIRVCALN-KVGLGEATSVPGTVKPEDKLEAPEL 24024

Query: 1097  EVTETT---IVITWTPAPRIGFKLGVRPS-------QGGEAPREVTSDSG----SIVVSG 1142
             ++       IV+    + RI      RP+       + GE   +V  + G     + +  
Sbjct: 24025 DLDSELRKGIVVRAGGSARIHIPFKGRPTPEITWSREEGEFTDKVQIEKGVNYTQLSIDN 24084

Query: 1143  LTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHL-EANPDTGVLTVSWERSTTP 1201
                     Y +++      + A +  KV+    PP NL + E   D+  L   WE    P
Sbjct: 24085 CDRNDAGKYILKLENSSGSKSAFVTVKVLDTPGPPQNLAVKEVRKDSAFLV--WE---PP 24139

Query: 1202  DITGYRITTTPTNGQQGNSLEEVVHAD----QSSCTFDNLSPGLEYNVSVYTVKDDKESV 1257
              I G          ++ ++ +   +      ++S   +NL+ G  Y   V    +    V
Sbjct: 24140 IIDGGAKVKNYVIDKRESTRKAYANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFGVGV 24199

Query: 1258  PIS--DTIIPEVPQLTD--LSFVDITDSSIGLRWTPLN---SSTIIGYRITVVAAGEGIP 1310
             P+   D +    P      ++  D++ +S  L W        S ++GY   V    +G  
Sbjct: 24200 PVETVDAVKAAEPPSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLGY--VVEMQPKGTE 24257

Query: 1311  IFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTT---------LTQQTAVPPP 1361
              +    +S V    VTGL  G +Y   V      G+S P           LT Q ++  P
Sbjct: 24258 KWSIVAESKVCNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKLP 24317

Query: 1362  TDLRFTNIGPD---TMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTN 1418
              +      G D    + V   P P+I   +++    P+K       +++  +  + VL +
Sbjct: 24318 FNTYSIQAGEDLKIEIPVIGRPRPNI---SWVKDGEPLK---QTTRVNVEETATSTVL-H 24370

Query: 1419  LLPGTE------YVVSVSSVYEQHESTPLRGRQKTGLDSPTG-IDFSDITANSFTVHWIA 1471
             +  G +       V + +S     E+  +   +K G   P G + F +++A+   + W  
Sbjct: 24371 IKEGNKDDFGKYTVTATNSAGTATENLSVIVLEKPG--PPVGPVRFDEVSADFVVISWEP 24428

Query: 1472  PRAT----ITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREE 1527
             P  T    I+ Y +    +  +          +R +I +T L  GTEY   I A N   +
Sbjct: 24429 PAYTGGCQISNYIVEKR-DTTTTTWHMVSATVARTTIKITKLKTGTEYQFRIFAENRYGK 24487

Query: 1528  SPLLIGQQSTVS------DVPRDLEVVAATPTSLLISWDAP----AVTVRYYRITYGETG 1577
             S  L  +   V         P    V + +   +L+ W  P       +  Y +   E  
Sbjct: 24488 SAPLDSKAVIVQYPFKEPGPPGTPFVTSISKDQMLVQWHEPVNDGGTKIIGYHLEQKEKN 24547

Query: 1578  GNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPS 1637
                 V+    P   +    +GL  G++Y   V A    G    S        R   D P 
Sbjct: 24548 SILWVKLNKTPIQDTKFKTTGLDEGLEYEFKVSAENIVGIGKPSKVSECFVARDPCDPPG 24607

Query: 1638  QMQVTDVQDNSISVKW----LPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGL 1693
             + +   +  N++++KW        S +TGY V           K       +TE T+ GL
Sbjct: 24608 RPEAIVITRNNVTLKWKKPAYDGGSKITGYIVEKKDLPDGRWMKASFTNVLETEFTVSGL 24667

Query: 1694  QPTVEYVVSVYAQNPSGE-SQPLVQT-AVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVS 1751
                  Y   V A+N +G  S+P   + A+T  D        ++D  +  +  +     V 
Sbjct: 24668 VEDQRYEFRVIARNAAGNFSEPSDSSGAITARD--------EIDAPNASLDPKYKDVIVV 24719

Query: 1752  RYRVTYSSPED----GIHELFPAPDGE--EDTAELQGLRPGSEYTVSVV--ALHDD---- 1799
                 T+    D     I ++  + DG+  E+TA    ++   + T  VV   +  D    
Sbjct: 24720 HAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQY 24779

Query: 1800  -MESQPLIGTQSTAI-------PAPTD--LKFTQVTPTSLSAQWTPPNVQLTGYRVR--V 1847
              ++   + GT+S  I       P P +  LK T VT       W PP +Q  G  +   +
Sbjct: 24780 ILKLSNVGGTKSIPITVKVLDRPGPPEGPLKVTGVTAEKCYLAWNPP-LQDGGANISHYI 24838

Query: 1848  TPKEKTGPMK--EINLAPDSSSVVVSGLMVATKY-----EVSVYALKDTLTSRPAQGVVT 1900
               K +T  +   +++    + +  V+ L+   +Y      V+ Y + + L S P      
Sbjct: 24839 IEKRETSRLSWTQVSTEVQALNYKVTKLLPGNEYIFRVMAVNKYGIGEPLESGPVT-ACN 24897

Query: 1901  TLENVSPPRRARVTDATETTITISWRTKTE----TITGFQVDAVPANG--QTPIQRTIKP 1954
               +   PP    V+  T+ ++ ++W    +     I G+ ++     G   T   +    
Sbjct: 24898 PYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDKEGVRWTKCNKKTLT 24957

Query: 1955  DVRSYTITGLQPGTDYKIYLYTLNDNARSSPV-------VIDASTAIDAPSNLRFLATTP 2007
             D+R   +TGL  G  Y+  +   N      P          DA      PSN +   T+ 
Sbjct: 24958 DLR-LRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRACDALYPPGPPSNPKVTDTSR 25016

Query: 2008  NSLLVSWQPP----RARITGYIIKYEKPGSPPREVVPRPRPGV--TEATITGLEPGTEYT 2061
             +S+ ++W  P     A + GY+++  K  +        P  G+   + T+T L+  TEY 
Sbjct: 25017 SSVSLAWSKPIYDGGAPVKGYVVEV-KEAAADEWTTCTPPTGLQGKQFTVTKLKENTEYN 25075

Query: 2062  IYVIALKNNQKSEP 2075
               + A+ +    EP
Sbjct: 25076 FRICAINSEGVGEP 25089



 Score =  123 bits (309), Expect = 2e-27
 Identities = 314/1502 (20%), Positives = 546/1502 (36%), Gaps = 190/1502 (12%)

Query: 619   TPSQPNSHPIQWNAP---QPSHISKYILRWRPKNSVGRWKEATIPGHLNS--YTIKGLKP 673
             T +  +S  + W+ P     + +  Y++  + + +   W   T P  L    +T+  LK 
Sbjct: 25012 TDTSRSSVSLAWSKPIYDGGAPVKGYVVEVK-EAAADEWTTCTPPTGLQGKQFTVTKLKE 25070

Query: 674   GVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITA 733
                Y  ++ +I   G  E        T   + V    +     P   L A    V  + A
Sbjct: 25071 NTEYNFRICAINSEGVGE------PATLPGSVVAQERIE---PPEIELDADLRKVVVLRA 25121

Query: 734   SSFVVSWVSASDTVSGFRVEYELSEEGDEP-----QYLDLPSTATSVNIPDLLPGRKYIV 788
             S+ +  +V    T+ G R E E+  E  E        +++ S+ T + I ++        
Sbjct: 25122 SATLRLFV----TIKG-RPEPEVKWEKAEGILTDRAQIEVTSSFTMLVIDNVTRFDSGRY 25176

Query: 789   NVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ----APITGYRIV 844
             N+   +  G ++  ++     +P AP + T+ +V   S+ + W  P     A IT Y + 
Sbjct: 25177 NLTLENNSGSKTAFVNVRVLDSPSAPVNLTIREVKKDSVTLSWEPPLIDGGAKITNYIVE 25236

Query: 845   YSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRS 904
                +   +   +    T  +  + +LQ G  Y   + A  E     P     ETT   + 
Sbjct: 25237 KRETTRKAYATITNNCTKTTFRIENLQEGCSYYFRVLASNEYGIGLPA----ETTEPVKV 25292

Query: 905   DTVPSPRD-LQFVEVTDVKVTIMWTPPES----AVTGYRVDVIPVNLPGEHGQRLPISRN 959
                P P   +  V+VT    TI W  PES     +TGY V++       E        + 
Sbjct: 25293 SEPPLPPGRVTLVDVTRNTATIKWEKPESDGGSKITGYVVEMQTKG--SEKWSTCTQVKT 25350

Query: 960   TFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWT- 1018
               A ++GL+ G  Y F+V AV+    S P       +L  P   + +    S  L   T 
Sbjct: 25351 LEATISGLTAGEEYVFRVAAVNEKGRSDP------RQLGVPVIARDIEIKPSVELPFHTF 25404

Query: 1019  --PPRAQIT-------GYRLTVGLTRRGQP----RQYNVGPSVSKYPLRNLQPASEYTVS 1065
                 R Q+          + TV   + GQ      + NV  S +   L +++ AS+  V 
Sbjct: 25405 NVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSL-SIKEASKEDVG 25463

Query: 1066  LVAIKGNQESPKATGVFTTL---QPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPS 1122
                +  +  +   T   T +   +PG   P    EV+  +I I+W P    G   G + S
Sbjct: 25464 TYELCVSNSAGSITVPITIIVLDRPGPPGPIRIDEVSCDSITISWNPPEYDG---GCQIS 25520

Query: 1123  QGGEAPREVTSDSGSIV----------VSGLTPGVEYVYTIQVL-RDGQ----ERDAPIV 1167
                   +E TS +  IV          +  LT G EY + +    R G+    E  A + 
Sbjct: 25521 NYIVEKKETTSTTWHIVSQAVARTSIKIVRLTTGSEYQFRVCAENRYGKSSYSESSAVVA 25580

Query: 1168  NKVVTPLSPP-TNLHLEANPDTGVLTVSWERSTTPD---ITGYRITTTPTNGQQGNSLEE 1223
                 +P  PP T   + A   T  + V+W+         + GY +     +    +   +
Sbjct: 25581 EYPFSPPGPPGTPKVVHATKST--MLVTWQVPVNDGGSRVIGYHLEYKERSSILWSKANK 25638

Query: 1224  VVHADQSSCTFDNLSPGLEYNVSVYT--------VKDDKESVPISDTIIPE-VPQLTDLS 1274
             ++ AD +      L  GL Y   VY              E VP  D   P   P++T+  
Sbjct: 25639 ILIAD-TQMKVSGLDEGLMYEYRVYAENIAGIGKCSKSCEPVPARDPCDPPGQPEVTN-- 25695

Query: 1275  FVDITDSSIGLRWTPLN---SSTIIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPG 1331
                IT  S+ L+W+  +    + I GY +      +G  +  ++ +    Y+ VT L   
Sbjct: 25696 ---ITRKSVSLKWSKPHYDGGAKITGYIVERRELPDGRWLKCNYTNIQETYFEVTELTED 25752

Query: 1332  IDYDISVI------TLINGGESAPTTLTQQTAVPPPT--DLRFTNI----GPDTMRVT-- 1377
               Y+  V       ++    ES    + +    PP    D++F ++      + +++   
Sbjct: 25753 QRYEFRVFARNAADSVSEPSESTGPIIVKDDVEPPRVMMDVKFRDVIVVKAGEVLKINAD 25812

Query: 1378  --WAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNL----LPGTEYVVSVSS 1431
                 P P I      +        E+ A   I  +DN  +LT          +YV+++ +
Sbjct: 25813 IAGRPLPVISWAKDGIEI------EERARTEIISTDNHTLLTVKDCIRRDTGQYVLTLKN 25866

Query: 1432  VYEQHE-STPLRGRQKTGLDSPTG-IDFSDITANSFTVHWIAPR----ATITGYRI-RHH 1484
             V      +   +   K G   P G ++ + +TA   ++ W  P+    A I  Y + +  
Sbjct: 25867 VAGTRSVAVNCKVLDKPG--PPAGPLEINGLTAEKCSLSWGRPQEDGGADIDYYIVEKRE 25924

Query: 1485  PEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGR------EESPLLIGQQSTV 1538
               H +    E  +     S  +T L  G EY+  +  +N        E   +      TV
Sbjct: 25925 TSHLAWTICEGEL--QMTSCKVTKLLKGNEYIFRVTGVNKYGVGEPLESVAIKALDPFTV 25982

Query: 1539  SDVPRDLEVVAATPTSLLISWDAP----AVTVRYYRITYGETGGNSPVQEFTVPGSKSTA 1594
                P  LE+ + T  S+ + W  P       +  Y I   E      V+    P      
Sbjct: 25983 PSPPTSLEITSVTKESMTLCWSRPESDGGSEISGYIIERREKNSLRWVRVNKKPVYDLRV 26042

Query: 1595  TISGLKPGVDYTITVYAVTGRGDS-PASSKPISINYRTEI---DKPSQMQVTDVQDNSIS 1650
               +GL+ G +Y   VYA    G S P+ + P+ I     +     PS+ ++ D    +I+
Sbjct: 26043 KSTGLREGCEYEYRVYAENAAGLSLPSETSPL-IRAEDPVFLPSPPSKPKIVDSGKTTIT 26101

Query: 1651  VKWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQ 1706
             + W+       +P+TGY V    K+     KT       TE TI GL    EYV  V + 
Sbjct: 26102 IAWVKPLFDGGAPITGYTVEYK-KSDDTDWKTSIQSLRGTEYTISGLTTGAEYVFRVKSV 26160

Query: 1707  NPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRY---------RVTY 1757
             N  G S P   +        +     D+D +  K          +            V +
Sbjct: 26161 NKVGASDPSDSSDPQIAKEREEEPLFDIDSEMRKTLIVKAGASFTMTVPFRGRPVPNVLW 26220

Query: 1758  SSPEDGIHELFPAPDGEEDTA---ELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIP 1814
             S P+  +         +  T+   E        +YT+++  +        ++    T  P
Sbjct: 26221 SKPDTDLRTRAYVDTTDSRTSLTIENANRNDSGKYTLTIQNVLSAASLTLVVKVLDTPGP 26280

Query: 1815  APTDLKFTQVTPTSLSAQWTPP----NVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVV 1870
              PT++    VT  S    W  P       +  Y +      K   +   N   +  S  V
Sbjct: 26281 -PTNITVQDVTKESAVLSWDVPENDGGAPVKNYHIEKREASKKAWVSVTNNC-NRLSYKV 26338

Query: 1871  SGLMVATKYEVSVYALKDTLTSRPA---QGVVTTLENVSPPRRARVTDATETTITISW-- 1925
             + L     Y   V    +     PA   +GV  T E  SPP +  VT  ++ +++++W  
Sbjct: 26339 TNLQEGAIYYFRVSGENEFGVGIPAETKEGVKIT-EKPSPPEKLGVTSISKDSVSLTWLK 26397

Query: 1926  --RTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARS 1983
                     I  + V+A+    +  ++  +      + ++GL+  ++Y   ++  N    S
Sbjct: 26398 PEHDGGSRIVHYVVEALEKGQKNWVKCAVAKSTH-HVVSGLRENSEYFFRVFAENQAGLS 26456

Query: 1984  SP 1985
              P
Sbjct: 26457 DP 26458



 Score =  122 bits (307), Expect = 3e-27
 Identities = 331/1598 (20%), Positives = 562/1598 (35%), Gaps = 189/1598 (11%)

Query: 624   NSHPIQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNS--YTIKGLKPGVVYE 678
             NS  + W  P+    S I +YIL  R K S  RW +      ++   + + GL  G  YE
Sbjct: 28166 NSITLTWARPESDGGSEIQQYILERREKKST-RWVKVISKRPISETRFKVTGLTEGNEYE 28224

Query: 679   GQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVV 738
               +++    G    +           PV          P  P V     VT+ + ++  +
Sbjct: 28225 FHVMAENAAGVGPASGIS-RLIKCREPVNP--------PGPPTVV---KVTDTSKTTVSL 28272

Query: 739   SW----VSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQIS 794
              W          + G+ +E   ++ GD  +        T   + DL  G +Y   V  I+
Sbjct: 28273 EWSKPVFDGGMEIIGYIIEMCKADLGDWHKVNAEACVKTRYTVTDLQAGEEYKFRVSAIN 28332

Query: 795   EDGEQSLILSTSQTTAPD--APPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGS 852
               G+      T    A D    P+  +D     + VVR          Y+   +P+   S
Sbjct: 28333 GAGKGDSCEVTGTIKAVDRLTAPELDIDANFKQTHVVRAGASIRLFIAYQGRPTPTAVWS 28392

Query: 853   STELNLPETANSVTLSDLQPGVQYNIT-------IYAVEENQESTPVVIQQETTGTPRSD 905
               + NL   A+  T          N            VE N  S  +    +   TP   
Sbjct: 28393 KPDSNLSLRADIHTTDSFSTLTVENCNRNDAGKYTLTVENNSGSKSITFTVKVLDTPGP- 28451

Query: 906   TVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPGEHGQRLPISRNTF 961
                 P  + F +VT    T+MW  P     + +  Y V+    +           +R  F
Sbjct: 28452 ----PGPITFKDVTRGSATLMWDAPLLDGGARIHHYVVEKREASRRSWQVISEKCTRQIF 28507

Query: 962   AEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQ----TTKLDAPTNLQFVNETDSTVLVRW 1017
              +V  L+ GV YYF+V AV+     +P    +    T +   P  L  V+ + S+ ++ W
Sbjct: 28508 -KVNDLAEGVPYYFRVSAVNEYGVGEPYEMPEPIVATEQPAPPRRLDVVDTSKSSAVLAW 28566

Query: 1018  TPP----RAQITGYRLTVGLTRRGQPRQYNVGPSVS-KYPLRNLQPASEY---------- 1062
               P     ++ITGY L   + ++G       G +    + +  L   +EY          
Sbjct: 28567 LKPDHDGGSRITGYLLE--MRQKGSDFWVEAGHTKQLTFTVERLVEKTEYEFRVKAKNDA 28624

Query: 1063  -------TVSLVAIKGNQESPKA--TGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRI 1113
                      S V IK  Q  P A  TG+   L    +  P+  +V      I+  PAP++
Sbjct: 28625 GYSEPREAFSSVIIKEPQIEPTADLTGITNQLITCKAGSPFTIDVP-----ISGRPAPKV 28679

Query: 1114  GFKL-GVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVT 1172
              +KL  +R  +        T D  ++ V     G    Y + +      +   +   V+ 
Sbjct: 28680 TWKLEEMRLKETDRVSITTTKDRTTLTVKDSMRGDSGRYFLTLENTAGVKTFSVTVVVIG 28739

Query: 1173  PLSPPTNLHLEANPDTGVLTVSW---ERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQ 1229
                P T     ++       +SW   +     +IT Y +    +       +   V   Q
Sbjct: 28740 RPGPVTGPIEVSSVSAESCVLSWGEPKDGGGTEITNYIVEKRESGTTAWQLVNSSVKRTQ 28799

Query: 1230  SSCTFDNLSPGLEYNVSV-----YTVKDDKESVPI---SDTIIPEVPQLTDLSFVDITDS 1281
                T  +L+  +EY+  V     + V    ES PI      + P  P  T      ++ +
Sbjct: 28800 IKVT--HLTKYMEYSFRVSSENRFGVSKPLESAPIIAEHPFVPPSAP--TRPEVYHVSAN 28855

Query: 1282  SIGLRWTPL---NSSTIIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISV 1338
             ++ +RW        S IIGY +        + + E+ V      Y VTGL  G++Y    
Sbjct: 28856 AMSIRWEEPYHDGGSKIIGYWVEKKERNTILWVKENKVPCLECNYKVTGLVEGLEYQFRT 28915

Query: 1339  ITLINGGES----APTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAPPP---SIDLTNFLV 1391
               L   G S    A   +  Q  V  P     T++   T+ + W+ P       +  +++
Sbjct: 28916 YALNAAGVSKASEASRPIMAQNPVDAPGRPEVTDVTRSTVSLIWSAPAYDGGSKVVGYII 28975

Query: 1392  RYSPVKNEEDVAELSIS---PSDNAVVLTNLLPGTEYVVSVSS------VYEQHEST-PL 1441
                PV    D   L  +    SDN   +T L  G  Y   V +      + +  EST P+
Sbjct: 28976 ERKPVSEVGDGRWLKCNYTIVSDNFFTVTALSEGDTYEFRVLAKNAAGVISKGSESTGPV 29035

Query: 1442  RGRQ-----KTGLDSPTGIDFSDITANSFTVHWIA----PRATITGYRIRHHPEHFSGRP 1492
               R      K  LD+    D   I A S  V   A    P   I   +     +      
Sbjct: 29036 TCRDEYAPPKAELDARLHGDLVTIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVS 29095

Query: 1493  REDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVP---RDLEVVA 1549
              +     +   I   + +   +Y +++   +G +   +++     V D P     L V  
Sbjct: 29096 LQYTGKRATAVIKFCDRSDSGKYTLTVKNASGTKAVSVMV----KVLDSPGPCGKLTVSR 29151

Query: 1550  ATPTSLLISWDAP----AVTVRYYRITYGETGGNSPVQEFTVPGSKSTAT--ISGLKPGV 1603
              T     ++W  P       + +Y +   ET   S +    V G   T +  ++ L    
Sbjct: 29152 VTQEKCTLAWSLPQEDGGAEITHYIVERRET---SRLNWVIVEGECPTLSYVVTRLIKNN 29208

Query: 1604  DYTITVYAVTGRGDS-PASSKPI-SINYRTEIDKPSQMQVTDVQDNSISVKWLPSSS--- 1658
             +Y   V AV   G   P  S+PI + N  T    P   +        I ++W    S   
Sbjct: 29209 EYIFRVRAVNKYGPGVPVESEPIVARNSFTIPSPPGIPEEVGTGKEHIIIQWTKPESDGG 29268

Query: 1659  -PVTGYRVTTTPKNGPGPTK-TKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLV 1716
               ++ Y V    K     T+  K      T + +  L    +Y   V A N +G S+P  
Sbjct: 29269 NEISNYLVDKREKKSLRWTRVNKDYVVYDTRLKVTSLMEGCDYQFRVTAVNAAGNSEPSE 29328

Query: 1717  QTAVTNIDR-------PKGLAFTDVDVDSIKIAWESPQGQVSRYRVTY-----SSPEDGI 1764
              +   +          P      D    SI +AW  P        V Y         D  
Sbjct: 29329 ASNFISCREPSYTPGPPSAPRVVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDTDQW 29388

Query: 1765  HELFPAPDGEEDTAELQGLRPGSEYTVSVVALH---------DDMESQPLIGTQSTAIPA 1815
             + +            +  L+ G +Y+  V A++            E +P+   +   +  
Sbjct: 29389 YRVHTNATIRNTEFTVPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEIPDLEL 29448

Query: 1816  PTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTG---PMKEINLAPDSSSVVVSG 1872
               DLK T       S +     V ++G    V    K G     + I    +S S+++  
Sbjct: 29449 ADDLKKTVTIRAGASLRLM---VSVSGRPPPVITWSKQGIDLASRAIIDTTESYSLLI-- 29503

Query: 1873  LMVATKYEVSVYALKDTLTS--RPAQGVVTTLENVSPPRRARVTDATETTITISWRTKT- 1929
             +    +Y+   Y ++    S  + A  +V   +   P    +V + +  ++TI+W   T 
Sbjct: 29504 VDKVNRYDAGKYTIEAENQSGKKSATVLVKVYDTPGPCPSVKVKEVSRDSVTITWEIPTI 29563

Query: 1930  ---ETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKI-----YLYTLNDNA 1981
                  +  + V+   A  +     T K     Y I+GL  GT Y        +Y + +  
Sbjct: 29564 DGGAPVNNYIVEKREAAMRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYGIGEPC 29623

Query: 1982  RSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPP----RARITGYIIKYEKPGSPPRE 2037
              +S  V+ +   +  P+ L  +  T +++ ++W+ P     +R+TGY+++  K G+    
Sbjct: 29624 ETSDAVLVSEVPL-VPAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGTERWM 29682

Query: 2038  VVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEP 2075
              V   +P V E T+T L  G +Y   + A      SEP
Sbjct: 29683 KVVTLKPTVLEHTVTSLNEGEQYLFRIRAQNEKGVSEP 29720



 Score =  120 bits (301), Expect = 2e-26
 Identities = 286/1368 (20%), Positives = 511/1368 (37%), Gaps = 206/1368 (15%)

Query: 866   TLSDLQPGVQYNITIYAVEENQEST-PVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVT 924
             T++ L  G +Y   + A  EN+  T P    +      + D    P   +  +V+  ++T
Sbjct: 18356 TVTRLIEGNEYIFRVRA--ENKIGTGPPTESKPVIAKTKYDKPGRPDPPEVTKVSKEEMT 18413

Query: 925   IMWTPPE----SAVTGYRVDVIPVNLPGEHGQR-LPISRNTFAE----VTGLSPGVTYYF 975
             ++W PPE     ++TGY ++        +H  R +P++++   E    V  L P   Y F
Sbjct: 18414 VVWNPPEYDGGKSITGYFLEK-----KEKHSTRWVPVNKSAIPERRMKVQNLLPDHEYQF 18468

Query: 976   KVFAVSH------GRESKPLTAQQTTKLDAP-TNLQFVNETDSTVLVRWTPP----RAQI 1024
             +V A +          S+P+ A+   +   P TN + V+ T  ++ + W  P     A I
Sbjct: 18469 RVKAENEIGIGEPSLPSRPVVAKDPIEPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAPI 18528

Query: 1025  TGY------RLTVGLTRRGQPRQYNVGPSVSK-YPLRNLQPASEYTVSL-----VAIKGN 1072
              GY      ++       G  R       V K + + +L    EY   +     V I   
Sbjct: 18529 IGYVVEMRPKIADASPDEGWKRCNAAAQLVRKEFTVTSLDENQEYEFRVCAQNQVGIGRP 18588

Query: 1073  QESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWT-------------PAPRIGFKLGV 1119
              E  +A      L+P    P  + + +   +VI                PAP++ ++   
Sbjct: 18589 AELKEAIKPKEILEP----PEIDLDASMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVG 18644

Query: 1120  RPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTN 1179
               +   +   ++      +V+   T      Y++ ++    E+   +  +V+    P ++
Sbjct: 18645 IDNVVRKGQVDLVDTMAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFVNVRVLDTPGPVSD 18704

Query: 1180  LHLEANPDTGVLTVSW---ERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDN 1236
             L +     T    VSW   E      +T Y +     + +  +++   V   ++S    N
Sbjct: 18705 LKVSDVTKTSC-HVSWAPPENDGGSQVTHYIVEKREADRKTWSTVTPEVK--KTSFHVTN 18761

Query: 1237  LSPGLEYNVSVYTVKDDKESVPI--------SDTII-PEVPQLTDLSFVDITDSSIGLRW 1287
             L PG EY   V  V +    VP         SD +  P+ P+   L   ++T +S  L W
Sbjct: 18762 LVPGNEYYFRVTAVNEYGPGVPTDVPKPVLASDPLSEPDPPR--KLEVTEMTKNSATLAW 18819

Query: 1288  TPL---NSSTIIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLING 1344
              P      + I GY  +     +    + ++         VTGL+ G  Y   V      
Sbjct: 18820 LPPLRDGGAKIDGYITSYREEEQPADRWTEYSVVKDLSLVVTGLKEGKKYKFRVAARNAV 18879

Query: 1345  GESAPTTL-----TQQTAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVK-- 1397
             G S P         ++  +PP        + P+ + +       I+   +   +   K  
Sbjct: 18880 GVSLPREAEGVYEAKEQLLPPKI------LMPEQITIKAGKKLRIEAHVYGKPHPTCKWK 18933

Query: 1398  -NEEDV---AELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSP- 1452
               E++V   + L++  +D++ +L       +     S   E    T  +  +   +D+P 
Sbjct: 18934 KGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPG 18993

Query: 1453  ---TGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPH----SRNSIT 1505
                   D SDI A++ ++ W  P     G  I ++        R D V      ++ S  
Sbjct: 18994 PPQPPFDISDIDADACSLSWHIPLED-GGSNITNYIVEKCDVSRGDWVTALASVTKTSCR 19052

Query: 1506  LTNLTPGTEYVVSIVALN--GREE---SPLLIGQ-QSTVSDVPRDLEVVAATPTSLLISW 1559
             +  L PG EY+  + A N  G  E   SP ++ Q    V   P++  V       + ++W
Sbjct: 19053 VGKLIPGQEYIFRVRAENRFGISEPLTSPKMVAQFPFGVPSEPKNARVTKVNKDCIFVAW 19112

Query: 1560  DAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATI----------------SGLKPGV 1603
             D P            ++ G SP+  + +   +  + +                +GL  G+
Sbjct: 19113 DRP------------DSDGGSPIIGYLIERKERNSLLWVKANDTLVRSTEYPCAGLVEGL 19160

Query: 1604  DYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWL----PSSSP 1659
             +Y+  +YA+   G SP S     +  R  +D P + +V DV  +++S+ W        S 
Sbjct: 19161 EYSFRIYALNKAGSSPPSKPTEYVTARMPVDPPGKPEVIDVTKSTVSLIWARPKHDGGSK 19220

Query: 1660  VTGYRVTTTPKNGPGPTKTKTAGPD--QTEMTIEGLQPTVEYVVSVYAQN------PSGE 1711
             + GY V      G    +  TA     Q E T  GL+   +Y     A+       PS  
Sbjct: 19221 IIGYFVEACKLPGDKWVRCNTAPHQIPQEEYTATGLEEKAQYQFRAIARTAVNISPPSEP 19280

Query: 1712  SQP---LVQTAVTNIDRPKGL-------AFTDVDVDSIKIAWESPQGQVS-RYRVTYSSP 1760
             S P   L +     ID    +       A T+V +D+    +  P   VS +   T   P
Sbjct: 19281 SDPVTILAENVPPRIDLSVAMKSLLTVKAGTNVCLDA--TVFGKPMPTVSWKKDGTLLKP 19338

Query: 1761  EDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPA-PTDL 1819
              +GI     A      T EL  +        ++ A +        I  +    P  P  +
Sbjct: 19339 AEGIK---MAMQRNLCTLELFSVNRKDSGDYTITAENSSGSKSATIKLKVLDKPGPPASV 19395

Query: 1820  KFTQVTPTSLSAQWTPP----NVQLTGYRVRVTPKEKTGP-MKEINLAPDSSSVVVSGLM 1874
             K  ++        W PP      ++T Y   V  +E + P   +++     +S  V  L+
Sbjct: 19396 KINKMYSDRAMLSWEPPLEDGGSEITNY--IVDKRETSRPNWAQVSATVPITSCSVEKLI 19453

Query: 1875  VATKYEVSV-----YALKDTLTSRPAQGVVTTLENVSPPRRAR---VTDATETTITISWR 1926
                +Y+  +     Y + D + + PA           PP R     +++ T+  +T+SW+
Sbjct: 19454 EGHEYQFRICAENKYGVGDPVFTEPA----IAKNPYDPPGRCDPPVISNITKDHMTVSWK 19509

Query: 1927  TKTE----TITGFQVDAVPANGQTPIQRTIKPDV-RSYTITGLQPGTDYKIYLYTLNDNA 1981
                +     ITG+ ++          +   KP + R+   TGLQ GT+Y+  +  +N   
Sbjct: 19510 PPADDGGSPITGYLLEKRETQAVNWTKVNRKPIIERTLKATGLQEGTEYEFRVTAINKAG 19569

Query: 1982  RSSPVVIDASTAIDA---------PSNLRFLATTPNSLLVSWQPPR----ARITGYIIKY 2028
                P   DAS A  A         P+  +   TT +S+ +SW  P     + I GY+++ 
Sbjct: 19570 PGKP--SDASKAAYARDPQYPPGPPAFPKVYDTTRSSVSLSWGKPAYDGGSPIIGYLVEV 19627

Query: 2029  EKPGSPPREVVPRPRP-GVTEATITGLEPGTEYTIYVIALKNNQKSEP 2075
             ++  S        P+    T   +TGL   T+Y   V A+     S+P
Sbjct: 19628 KRADSDNWVRCNLPQNLQKTRFEVTGLMEDTQYQFRVYAVNKIGYSDP 19675



 Score =  120 bits (301), Expect = 2e-26
 Identities = 304/1512 (20%), Positives = 534/1512 (35%), Gaps = 204/1512 (13%)

Query: 718   FSPLVATSESVTEITASSFVVSW----VSASDTVSGFRVEYELSEEGDEPQYLDLPSTA- 772
             F P   T+  + + T +S  ++W          + G+ VE  + +  +E   +  P T  
Sbjct: 23918 FKPGPPTNAHIVDTTKNSITLAWGKPIYDGGSEILGYVVE--ICKADEEEWQIVTPQTGL 23975

Query: 773   --TSVNIPDLLPGRKYIVNVYQISEDG--EQSLILSTSQTTAPDAPPDPTVDQVDDTSIV 828
               T   I  L   ++Y + V  +++ G  E + +  T +       P+  +D      IV
Sbjct: 23976 RVTRFEISKLTEHQEYKIRVCALNKVGLGEATSVPGTVKPEDKLEAPELDLDSELRKGIV 24035

Query: 829   VRW---SRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYN-ITIYAVE 884
             VR    +R   P  G     +P +  S  E    +         ++ GV Y  ++I   +
Sbjct: 24036 VRAGGSARIHIPFKGRP---TPEITWSREEGEFTDKVQ------IEKGVNYTQLSIDNCD 24086

Query: 885   ENQESTPVVIQQETTGTPRS-------DTVPSPRDLQFVEVTDVKVTIMWTPP----ESA 933
              N     ++  + ++G+  +       DT   P++L   EV      ++W PP     + 
Sbjct: 24087 RNDAGKYILKLENSSGSKSAFVTVKVLDTPGPPQNLAVKEVRKDSAFLVWEPPIIDGGAK 24146

Query: 934   VTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQ 993
             V  Y +D                S+ +F +V  L+ G  YYF+V A +      P+    
Sbjct: 24147 VKNYVIDKRESTRKAYANVSSKCSKTSF-KVENLTEGAIYYFRVMAENEFGVGVPVETVD 24205

Query: 994   TTKLDAPTN------LQFVNETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYN 1043
               K   P +      L  V++T ++++  W  P     +++ GY   V +  +G  +   
Sbjct: 24206 AVKAAEPPSPPGKVTLTDVSQTSASLM--WEKPEHDGGSRVLGY--VVEMQPKGTEKWSI 24261

Query: 1044  VGPS-VSKYPLRNLQPASEYTVSLVAIKGNQES-PKATGVFT-----TLQPGSSIPPYNT 1096
             V  S V    +  L    EY   + A     +S P+  GV       T+QP   +P +NT
Sbjct: 24262 VAESKVCNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKLP-FNT 24320

Query: 1097  ------EVTETTIVITWTPAPRIGF-KLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEY 1149
                   E  +  I +   P P I + K G    Q      E T+ S  + +         
Sbjct: 24321 YSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFG 24380

Query: 1150  VYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTP---DITGY 1206
              YT+            +   V+    PP             + +SWE         I+ Y
Sbjct: 24381 KYTVTATNSAGTATENLSVIVLEKPGPPVGPVRFDEVSADFVVISWEPPAYTGGCQISNY 24440

Query: 1207  RITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTII-- 1264
              +    T     + +   V   +++     L  G EY   ++      +S P+    +  
Sbjct: 24441 IVEKRDTTTTTWHMVSATVA--RTTIKITKLKTGTEYQFRIFAENRYGKSAPLDSKAVIV 24498

Query: 1265  ---------PEVPQLTDLSFVDITDSSIGLRW-TPLNS--STIIGYRITVVAAGEGIPIF 1312
                      P  P +T +S        + ++W  P+N   + IIGY +        + + 
Sbjct: 24499 QYPFKEPGPPGTPFVTSIS-----KDQMLVQWHEPVNDGGTKIIGYHLEQKEKNSILWVK 24553

Query: 1313  EDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQ----QTAVPPPTDLRFTN 1368
              +        +  TGL+ G++Y+  V      G   P+ +++    +    PP       
Sbjct: 24554 LNKTPIQDTKFKTTGLDEGLEYEFKVSAENIVGIGKPSKVSECFVARDPCDPPGRPEAIV 24613

Query: 1369  IGPDTMRVTWAPPP---SIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEY 1425
             I  + + + W  P       +T ++V     K+  D   +  S        TN+L  TE+
Sbjct: 24614 ITRNNVTLKWKKPAYDGGSKITGYIVEK---KDLPDGRWMKAS-------FTNVLE-TEF 24662

Query: 1426  VVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITG-YR---I 1481
              VS   V +Q     +  R   G  S        ITA        AP A++   Y+   +
Sbjct: 24663 TVS-GLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARD---EIDAPNASLDPKYKDVIV 24718

Query: 1482  RHHPEHF------SGRPREDRV--------------PHSRNSITLTNL-------TPGTE 1514
              H  E F       G+P  D V                 +++I  T L       T G +
Sbjct: 24719 VHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQ 24778

Query: 1515  YVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAP----AVTVRYYR 1570
             Y++ +  + G +  P+ +            L+V   T     ++W+ P       + +Y 
Sbjct: 24779 YILKLSNVGGTKSIPITVKVLDRPGPPEGPLKVTGVTAEKCYLAWNPPLQDGGANISHYI 24838

Query: 1571  ITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRG-DSPASSKPISI-N 1628
             I   ET   S  Q  T   + +   ++ L PG +Y   V AV   G   P  S P++  N
Sbjct: 24839 IEKRETSRLSWTQVSTEVQALNYK-VTKLLPGNEYIFRVMAVNKYGIGEPLESGPVTACN 24897

Query: 1629  YRTEIDKPSQMQVTDVQDNSISVKWL----PSSSPVTGYRVTTTPKNGPGPTKTKTAGPD 1684
                    PS  +V+ +  +S+ V W        + + GY +    K G   TK       
Sbjct: 24898 PYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDKEGVRWTKCNKKTLT 24957

Query: 1685  QTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQT-------AVTNIDRPKGLAFTDVDVD 1737
                + + GL     Y   V A+N +G  +P   +       A+     P     TD    
Sbjct: 24958 DLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRACDALYPPGPPSNPKVTDTSRS 25017

Query: 1738  SIKIAWESP----QGQVSRYRVTYSSPEDGIHELFPAPDGEEDTA-ELQGLRPGSEYTVS 1792
             S+ +AW  P       V  Y V               P G +     +  L+  +EY   
Sbjct: 25018 SVSLAWSKPIYDGGAPVKGYVVEVKEAAADEWTTCTPPTGLQGKQFTVTKLKENTEYNFR 25077

Query: 1793  VVALHDDMESQPL-----IGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRV 1847
             + A++ +   +P      +  Q    P   +L         L A  T         R+ V
Sbjct: 25078 ICAINSEGVGEPATLPGSVVAQERIEPPEIELDADLRKVVVLRASAT--------LRLFV 25129

Query: 1848  TPKEKTGPM----KEINLAPDSSSVVVSGLMV------ATKYEVSVY--ALKDTLTSRPA 1895
             T K +  P     K   +  D + + V+           T+++   Y   L++   S+ A
Sbjct: 25130 TIKGRPEPEVKWEKAEGILTDRAQIEVTSSFTMLVIDNVTRFDSGRYNLTLENNSGSKTA 25189

Query: 1896  QGVVTTLENVSPPRRARVTDATETTITISWRTKT----ETITGFQVDAVPANGQTPIQRT 1951
                V  L++ S P    + +  + ++T+SW          IT + V+      +     T
Sbjct: 25190 FVNVRVLDSPSAPVNLTIREVKKDSVTLSWEPPLIDGGAKITNYIVEKRETTRKAYATIT 25249

Query: 1952  IKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAP----SNLRFLATTP 2007
                   ++ I  LQ G  Y   +   N+     P        +  P      +  +  T 
Sbjct: 25250 NNCTKTTFRIENLQEGCSYYFRVLASNEYGIGLPAETTEPVKVSEPPLPPGRVTLVDVTR 25309

Query: 2008  NSLLVSWQPPRA----RITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIY 2063
             N+  + W+ P +    +ITGY+++ +  GS       + +    EATI+GL  G EY   
Sbjct: 25310 NTATIKWEKPESDGGSKITGYVVEMQTKGSEKWSTCTQVK--TLEATISGLTAGEEYVFR 25367

Query: 2064  VIALKNNQKSEP 2075
             V A+    +S+P
Sbjct: 25368 VAAVNEKGRSDP 25379



 Score =  119 bits (298), Expect = 4e-26
 Identities = 329/1550 (21%), Positives = 553/1550 (35%), Gaps = 222/1550 (14%)

Query: 601   PLQTYPSSSGPVEVFITETPSQPN-------SHPIQWNAPQ---PSHISKYILRWRPKNS 650
             P +T P       VF+   PS+P        +  I W  P     + I+ Y + ++  + 
Sbjct: 26068 PSETSPLIRAEDPVFLPSPPSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEYKKSDD 26127

Query: 651   VGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNT 710
                WK +        YTI GL  G  Y  ++ S+ + G  +        + +S P  +  
Sbjct: 26128 TD-WKTSIQSLRGTEYTISGLTTGAEYVFRVKSVNKVGASD-------PSDSSDPQIAKE 26179

Query: 711   VTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVS--GFRVEYELSEEGDEP----Q 764
                E     PL       +E+  +  V +  S + TV   G  V   L  + D       
Sbjct: 26180 REEE-----PLFDID---SEMRKTLIVKAGASFTMTVPFRGRPVPNVLWSKPDTDLRTRA 26231

Query: 765   YLDLPSTATSVNIPDLL--PGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQV 822
             Y+D   + TS+ I +       KY + +  +      +L++    T  P  P + TV  V
Sbjct: 26232 YVDTTDSRTSLTIENANRNDSGKYTLTIQNVLSAASLTLVVKVLDTPGP--PTNITVQDV 26289

Query: 823   DDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNI 878
                S V+ W  P+    AP+  Y I    + + +   +       S  +++LQ G  Y  
Sbjct: 26290 TKESAVLSWDVPENDGGAPVKNYHIEKREASKKAWVSVTNNCNRLSYKVTNLQEGAIYYF 26349

Query: 879   TIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAV 934
              +    E     P   ++   G   ++    P  L    ++   V++ W  PE    S +
Sbjct: 26350 RVSGENEFGVGIPAETKE---GVKITEKPSPPEKLGVTSISKDSVSLTWLKPEHDGGSRI 26406

Query: 935   TGYRVDVIPVNLPGEHGQR----LPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKP-- 988
               Y V+ +      E GQ+      ++++T   V+GL     Y+F+VFA +    S P  
Sbjct: 26407 VHYVVEAL------EKGQKNWVKCAVAKSTHHVVSGLRENSEYFFRVFAENQAGLSDPRE 26460

Query: 989   -LTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPS 1047
              L      +   P  +   N    TV VR         G  L V +   G+P    V  S
Sbjct: 26461 LLLPVLIKEQLEPPEIDMKNFPSHTVYVR--------AGSNLKVDIPISGKPLP-KVTLS 26511

Query: 1048  VSKYPLR-NLQPASEYTV---------SLVAIKGNQESPKATGVFTTL---------QPG 1088
                 PL+  ++  +E T          S+ A  G  E   A    TT          +PG
Sbjct: 26512 RDGVPLKATMRFNTEITAENLTINLKESVTADAGRYEITAANSSGTTKAFINIVVLDRPG 26571

Query: 1089  SSI-PPYNTEVTETTIVITWTPAPRIG-------FKLGVRPSQGGEAPREVTSDSGSIVV 1140
                 P   +++TE ++ + W P    G         L    S         T     + V
Sbjct: 26572 PPTGPVVISDITEESVTLKWEPPKYDGGSQVTNYILLKRETSTAVWTEVSATVARTMMKV 26631

Query: 1141  SGLTPGVEYVYTIQV-----LRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSW 1195
               LT G EY + I+      + D  +     V    T   PP+   +  N     +TV W
Sbjct: 26632 MKLTTGEEYQFRIKAENRFGISDHIDSACVTVKLPYTTPGPPSTPWV-TNVTRESITVGW 26690

Query: 1196  ERSTT---PDITGYRITTTPTNG---QQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYT 1249
                 +     + GY +     N    Q+ N L  V+       T   +S GL Y   VY 
Sbjct: 26691 HEPVSNGGSAVVGYHLEMKDRNSILWQKANKL--VIRTTHFKVT--TISAGLIYEFRVYA 26746

Query: 1250  V------KDDKESVPISDTIIPEVPQLTDLSFVDITDSSIGLRWTPL---NSSTIIGYRI 1300
                    K    S P+      E P+  ++   DI+ +S+ L W        S I GY +
Sbjct: 26747 ENAAGVGKPSHPSEPVLAIDACEPPR--NVRITDISKNSVSLSWQQPAFDGGSKITGYIV 26804

Query: 1301  TVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISV------------------ITLI 1342
                   +G      F + +   + ++GL     Y+  V                  IT I
Sbjct: 26805 ERRDLPDGRWTKASFTNVTETQFIISGLTQNSQYEFRVFARNAVGSISNPSEVVGPITCI 26864

Query: 1343  N--GGE--SAPTTLTQQTAVPPPTD--LRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPV 1396
             +  GG     P   T+       T   LR    G     + W        TN LV    V
Sbjct: 26865 DSYGGPVIDLPLEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALV---CV 26921

Query: 1397  KNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTG-I 1455
             +N  D+A + I  +D        L    Y + + +      +T +R +       P G I
Sbjct: 26922 ENTTDLASILIKDADR-------LNSGCYELKLRNAMGSASAT-IRVQILDKPGPPGGPI 26973

Query: 1456  DFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNS-------ITLTN 1508
             +F  +TA   T+ W  P A   G +I H   +   +    RV  S  S       IT T 
Sbjct: 26974 EFKTVTAEKITLLW-RPPADDGGAKITH---YIVEKRETSRVVWSMVSEHLEECIITTTK 27029

Query: 1509  LTPGTEYVVSIVALNGRE-----ESPLLIGQQSTVSDVPRDL-EVVAATPTSLLISWDAP 1562
             +  G EY+  + A+N        ES  ++ + + V+  P  + EV   T  S+ + W  P
Sbjct: 27030 IIKGNEYIFRVRAVNKYGIGEPLESDSVVAKNAFVTPGPPGIPEVTKITKNSMTVVWSRP 27089

Query: 1563  A------VTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRG 1616
                    ++  +      ++ G   V + T+  ++   T  GL    DY   V AV   G
Sbjct: 27090 IADGGSDISGYFLEKRDKKSLGWFKVLKETIRDTRQKVT--GLTENSDYQYRVCAVNAAG 27147

Query: 1617  DSPASSKPISINYRTEID---KPSQMQVTDVQDNSISVKW----LPSSSPVTGYRVTTTP 1669
               P S           ID    P+++++ D   +SI++ W        S VTGY V    
Sbjct: 27148 QGPFSEPSEFYKAADPIDPPGPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVVEIRQ 27207

Query: 1670  KNGPGPTKTKTAGPDQ-TEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKG 1728
                   T   T G  + TE  +  L+P V Y   V A N +G+ +P+       +     
Sbjct: 27208 GEEEEWTTVSTKGEVRTTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMN--EPVQAKDI 27265

Query: 1729  LAFTDVDVD-SIKIAWESPQGQVSRYRVTYSS--PEDGIHELFPAPDGEEDTAELQGLRP 1785
             L   ++D+D +++ +  +  G+  +  + +    P            G +    ++    
Sbjct: 27266 LEAPEIDLDVALRTSVIAKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYSIENTDS 27325

Query: 1786  GSEYTVSVVALHDDME---------SQPLIGTQSTAI----PAPTDLKFTQVTPTSLSAQ 1832
              S  T+  V  +D  +          +P   T S  +     A   L+   V+  +++  
Sbjct: 27326 SSLLTIPQVTRNDTGKYILTIENGVGEPKSSTVSVKVLDTPAACQKLQVKHVSRGTVTLL 27385

Query: 1833  WTPPNVQLTGYRVRVTPKEKTGPMKEINLAP---DSSSVVVSGLMVATKYEVSVYALKDT 1889
             W PP +      +    +++    +  ++      S+S  +  L   T +   V A  + 
Sbjct: 27386 WDPPLIDGGSPIINYVIEKRDATKRTWSVVSHKCSSTSFKLIDLSEKTPFFFRVLAENEI 27445

Query: 1890  LTSRPAQGV--VTTLENVSPPRRARVTDATETTITISWRTKTE-----TITGFQVDAVPA 1942
                 P +    V   E  +P R   + D+T+T++ +SW TK +      IT + V+    
Sbjct: 27446 GIGEPCETTEPVKAAEVPAPIRDLSMKDSTKTSVILSW-TKPDFDGGSVITEYVVERKGK 27504

Query: 1943  NGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDAST 1992
               QT     I        ++ L+  +  +  ++  N+   S PV I   T
Sbjct: 27505 GEQTWSHAGISKTC-EIEVSQLKEQSVLEFRVFAKNEKGLSDPVTIGPIT 27553



 Score =  118 bits (296), Expect = 6e-26
 Identities = 330/1625 (20%), Positives = 588/1625 (36%), Gaps = 230/1625 (14%)

Query: 611   PVEVFITETPSQPNSHPIQWNAP---QPSHISKYILRWRPKNSVGRWKEATIPGHLNSYT 667
             PV V + E     +S  + W  P     S I  Y+++ R       W   T      S+ 
Sbjct: 19790 PVNVTVKEISK--DSAYVTWEPPIIDGGSPIINYVVQKRDAERKS-WSTVTTECSKTSFR 19846

Query: 668   IKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSES 727
             +  L+ G  Y  ++ +  +YG  +               T + V    TP  P+V     
Sbjct: 19847 VANLEEGKSYFFRVFAENEYGIGDPGE------------TRDAVKASQTP-GPVVDLK-- 19891

Query: 728   VTEITASSFVVSWVS----ASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPG 783
             V  ++ SS  + W          + G+ V++ L+EE    + +   S +   +  DL  G
Sbjct: 19892 VRSVSKSSCSIGWKKPHSDGGSRIIGYVVDF-LTEENKWQRVMK--SLSLQYSAKDLTEG 19948

Query: 784   RKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWS---RPQAPITG 840
             ++Y   V   +E+GE +    T         PD  +  + D   + + +   R + PI G
Sbjct: 19949 KEYTFRVSAENENGEGTPSEITVVARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPIKG 20008

Query: 841   YRIVYSPSVE--------GSSTELNLPETANSVTLS--DLQPGV--QYNITIYAVEENQE 888
                  +PSV          + T +++  +A + TL   D Q     +Y IT+  V   +E
Sbjct: 20009 KP---APSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKE 20065

Query: 889   STPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPV 944
              T   I  +  G P   T P    ++F EVT   +T+ W PP+    S +T Y ++    
Sbjct: 20066 GT---ISIKVVGKPGIPTGP----IKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRD- 20117

Query: 945   NLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKV-----FAVSHGRESKPLTAQQTTKL-D 998
             ++  +        + T   VT L  G+ Y F+V     + V  G +S+P+ A+    + D
Sbjct: 20118 SVNNKWVTCASAVQKTTFRVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVPD 20177

Query: 999   APTNLQFVNETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGP-SVSKYPL 1053
             AP     V+    +V + WT P+    + ITGY L          ++ N  P  +  + +
Sbjct: 20178 APPPPNIVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTPIRMRDFKV 20237

Query: 1054  RNLQPASEYTVSLVAI------KGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITW 1107
               L    EY   ++AI      K +  S     +     PG    P    +T  ++ + W
Sbjct: 20238 TGLTEGLEYEFRVMAINLAGVGKPSLPSEPVVALDPIDPPGK---PEVINITRNSVTLIW 20294

Query: 1108  T-PAPRIGFKL-------GVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDG 1159
             T P    G KL          PS+       V     +  V+ L  G +Y + I+     
Sbjct: 20295 TEPKYDGGHKLTGYIVEKRDLPSKSWMKANHVNVPECAFTVTDLVEGGKYEFRIRAKNTA 20354

Query: 1160  QERDAPIVN----------KVVTPLSPPT---NLHLEANPDTGVLTV-----------SW 1195
                 AP  +          +  T +  PT    L ++A  DT VL             SW
Sbjct: 20355 GAISAPSESTETIICKDEYEAPTIVLDPTIKDGLTIKAG-DTIVLNAISILGKPLPKSSW 20413

Query: 1196  ERS----TTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVK 1251
              ++       DIT  +IT+TPT+     +++     D    T    +P        +  K
Sbjct: 20414 SKAGKDIRPSDIT--QITSTPTSSML--TIKYATRKDAGEYTITATNP--------FGTK 20461

Query: 1252  DDKESVPISDTIIPEVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGEGIPI 1311
              +   V + D  +P  P   ++S  +++     L WTP         +  ++   E   +
Sbjct: 20462 VEHVKVTVLD--VPGPPGPVEIS--NVSAEKATLTWTPPLEDGGSPIKSYILEKRETSRL 20517

Query: 1312  FEDFVDSSVG--YYTVTGLEPGIDYDISVITLINGG-----ESAPTTLTQQTAVP-PPTD 1363
                 V   +    +  T L  G +Y   V  + + G     +S P  +  +   P PP  
Sbjct: 20518 LWTVVSEDIQSCRHVATKLIQGNEYIFRVSAVNHYGKGEPVQSEPVKMVDRFGPPGPPEK 20577

Query: 1364  LRFTNIGPDTMRVTWAPP---PSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLL 1420
                +N+  +T  V+W  P      ++T + V     K+   V  +    SD    +T L 
Sbjct: 20578 PEVSNVTKNTATVSWKRPVDDGGSEITGYHVERREKKSLRWVRAIKTPVSDLRCKVTGLQ 20637

Query: 1421  PGTEYVVSVSSVYEQHESTPLRGRQKTGLDS-------PTGIDFSDITANSFTVHWIAPR 1473
              G+ Y   VS+        P        +         P+    +D T  S ++ W  P 
Sbjct: 20638 EGSTYEFRVSAENRAGIGPPSEASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLAWGKPH 20697

Query: 1474  ----ATITGYRIRHHPEHFSGRPREDRVPHSR-NSITLTNLTPGTEYVVSIVALN--GRE 1526
                   ITGY + H         ++      R     + +L    +Y   I A+N  G  
Sbjct: 20698 YDGGLEITGYVVEHQKVGDEAWIKDTTGTALRITQFVVPDLQTKEKYNFRISAINDAGVG 20757

Query: 1527  ESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFT 1586
             E  ++   +    ++  D E+ A    +L++      +++R +    G      P  E T
Sbjct: 20758 EPAVIPDVEIVEREMAPDFELDAELRRTLVV---RAGLSIRIFVPIKGR-----PAPEVT 20809

Query: 1587  -VPGSKSTATISGLKPGVDYTITVYAVTGRGD---------SPASSKPISINYRTEIDKP 1636
                 + +    + ++    +T+ +     R D         +PA  K   +N R  +D P
Sbjct: 20810 WTKDNINLKNRANIENTESFTLLIIPECNRYDTGKFVMTIENPAGKKSGFVNVRV-LDTP 20868

Query: 1637  S---QMQVTDVQDNSISVKW----LPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMT 1689
                  ++ TD+  +S+++ W    +   S +T Y V            T T    +    
Sbjct: 20869 GPVLNLRPTDITKDSVTLHWDLPLIDGGSRITNYIVEKREATRKS-YSTATTKCHKCTYK 20927

Query: 1690  IEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDR----PKGLAFTDVDVDSIKIAWES 1745
             + GL    EY   V A+N  G  +P   T           P  L   D+   ++ +AW  
Sbjct: 20928 VTGLSEGCEYFFRVMAENEYGIGEPTETTEPVKASEAPSPPDSLNIMDITKSTVSLAWPK 20987

Query: 1746  PQ----GQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHD--- 1798
             P+     +++ Y +                 G E    ++ L  G EYT  V+A++    
Sbjct: 20988 PKHDGGSKITGYVIEAQRKGSDQWTHITTVKGLE--CVVRNLTEGEEYTFQVMAVNSAGR 21045

Query: 1799  --DMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPM 1856
                 ES+P+I  + T +P        Q    + +       + + G R + T   K G  
Sbjct: 21046 SAPRESRPVIVKEQTMLPELDLRGIYQKLVIAKAGDNIKVEIPVLG-RPKPTVTWKKGDQ 21104

Query: 1857  -----KEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVS----- 1906
                  + +N    ++S +++ +    + +   Y     LT+R   G V  +  +      
Sbjct: 21105 ILKQTQRVNFETTATSTILN-INECVRSDSGPY----PLTARNIVGEVGDVITIQVHDIP 21159

Query: 1907  --PPRRARVTDATETTITISWRTKTE----TITGFQVDAVPANGQTPIQRTIKPDVRSYT 1960
               P    +  + +   +T SW          I+ + V+    +  T ++        +Y 
Sbjct: 21160 GPPTGPIKFDEVSSDFVTFSWDPPENDGGVPISNYVVEMRQTDSTTWVELATTVIRTTYK 21219

Query: 1961  ITGLQPGTDYKIYL-----YTLNDNARSSPVVIDASTAIDAPSNL-RFLATTPNSLLVSW 2014
              T L  G +Y+  +     Y +     S+ +V +    +  P    +  A T +S+ +SW
Sbjct: 21220 ATRLTTGLEYQFRVKAQNRYGVGPGITSACIVANYPFKVPGPPGTPQVTAVTKDSMTISW 21279

Query: 2015  QPP----RARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNN 2070
               P     + I GY ++ ++      + V +          +GL  G  Y   VIA    
Sbjct: 21280 HEPLSDGGSPILGYHVERKERNGILWQTVSKALVPGNIFKSSGLTDGIAYEFRVIAENMA 21339

Query: 2071  QKSEP 2075
              KS+P
Sbjct: 21340 GKSKP 21344



 Score =  116 bits (291), Expect = 2e-25
 Identities = 288/1381 (20%), Positives = 498/1381 (36%), Gaps = 191/1381 (13%)

Query: 766   LDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDT 825
             +D  +  TS  I +   G K    +   ++ G+    ++      P    +  V +  D 
Sbjct: 13045 IDTTAEQTSFRILEAKKGDKGRYKIVLQNKHGKAEGFINLKVIDVPGPVRNLEVTETFDG 13104

Query: 826   SIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETAN-SVTLSDLQPG-VQYNIT 879
              + + W  P     + I GY +V    ++  +  L      +   T++ LQ G V+Y   
Sbjct: 13105 EVSLAWEEPLTDGGSKIIGY-VVERRDIKRKTWVLATDRAESCEFTVTGLQKGGVEYLFR 13163

Query: 880   IYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVT 935
             + A        PV          + D    P ++   +V    V++ W PPE    + +T
Sbjct: 13164 VSARNRVGTGEPVETDNPVEARSKYDVPGPPLNVTITDVNRFGVSLTWEPPEYDGGAEIT 13223

Query: 936   GYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTT 995
              Y +++               + +  A VT +  G  Y F+V A +     KP  A    
Sbjct: 13224 NYVIELRDKTSIRWDTAMTVRAEDLSATVTDVVEGQEYSFRVRAQNRIGVGKPSAATPFV 13283

Query: 996   KL-------DAPTNLQFVNETDSTVLVRWTPP----RAQITGYRLTVGLTRRGQPR---- 1040
             K+         P NL   ++T S+V ++W PP     + I GY   +     G+      
Sbjct: 13284 KVADPIERPSPPVNLTSSDQTQSSVQLKWEPPLKDGGSPILGY--IIERCEEGKDNWIRC 13341

Query: 1041  QYNVGPSVSKYPLRNLQPASE--YTVSLVAIKGNQESPKATGVFTT----LQPGSSIPPY 1094
                + P ++ Y +  L+  ++  Y VS     G  +  +  G  T     ++P   +  +
Sbjct: 13342 NMKLVPELT-YKVTGLEKGNKYLYRVSAENKAGVSDPSEILGPLTADDAFVEPTMDLSAF 13400

Query: 1095  NTEV-----TETTIVI--TWTPAPRIGFKLGVRPSQGGEAPREVT-SDSGSIVVSGLTPG 1146
                +        TI++  T  P P   +  G +  + G+  +  T S    +V+S     
Sbjct: 13401 KDGLEVIVPNPITILVPSTGYPRPTATWCFGDKVLETGDRVKMKTLSAYAELVISPSERS 13460

Query: 1147  VEYVYTIQVLRDGQERDAPI-VNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPD--- 1202
              + +YT+++    +     I VN +  P +P      +   D+  LT  WE    PD   
Sbjct: 13461 DKGIYTLKLENRVKTISGEIDVNVIARPSAPKELKFGDITKDSVHLT--WE---PPDDDG 13515

Query: 1203  ---ITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSV------------ 1247
                +TGY +     + +    + + V       T  +L  G EY   V            
Sbjct: 13516 GSPLTGYVVEKREVSRKTWTKVMDFV--TDLEFTVPDLVQGKEYLFKVCARNKCGPGEPA 13573

Query: 1248  YTVKDDKESVPISDTIIPEVPQLTDLSFVDITDSSIGLRWTPLNS---STIIGYRITVVA 1304
             Y  +    S P +   +P+ P+  ++ + D T +SI L W P  +   S I GY +    
Sbjct: 13574 YVDEPVNMSTPAT---VPDPPE--NVKWRDRTANSIFLTWDPPKNDGGSRIKGYIVERCP 13628

Query: 1305  AGE------GIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQ--- 1355
              G       G P+ E  ++       VTGLE G  Y   V  L   G S P+  T++   
Sbjct: 13629 RGSDKWVACGEPVAETKME-------VTGLEEGKWYAYRVKALNRQGASKPSRPTEEIQA 13681

Query: 1356  --TAVPPPTDLRFTNIGPDTMR----------VTWAPPPSIDLTNFLVRYSPVKNEEDVA 1403
               T   P   L    +   T++          VT  P P I  T    +   +  ++   
Sbjct: 13682 VDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWT----KADMILKQDKRI 13737

Query: 1404  ELSISPSDNAVVLTNLL---PGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDI 1460
              +   P  + V + +      GT  + +V+          +    K G   P   D +D+
Sbjct: 13738 TIENVPKKSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNVLDKPG--PPAAFDITDV 13795

Query: 1461  TANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRNS------ITLTNLT 1510
             T  S  + W  PR    + IT Y +         R  +  V H  +S         T L 
Sbjct: 13796 TNESCLLTWNPPRDDGGSKITNYVVER-------RATDSEVWHKLSSTVKDTNFKATKLI 13848

Query: 1511  PGTEYVVSIVALN------GREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAP-- 1562
             P  EY+  + A N        + SP+    Q      P  LE    T  ++ ++W  P  
Sbjct: 13849 PNKEYIFRVAAENMYGVGEPVQASPITAKYQFDPPGPPTRLEPSDITKDAVTLTWCEPDD 13908

Query: 1563  --AVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYA--VTGRGDS 1618
                  +  Y +   +   +  V+   +P   +T  + GL     Y   V A  + G G  
Sbjct: 13909 DGGSPITGYWVERLDPDTDKWVRCNKMPVKDTTYRVKGLTNKKKYRFRVLAENLAGPGKP 13968

Query: 1619  PASSKPISINYRTEID---KPSQMQVTDVQDNSISVKWL----PSSSPVTGYRVTTTPKN 1671
               S++PI I  +  ID    P +  V DV   S+ + W        + +  Y V    K 
Sbjct: 13969 SKSTEPILI--KDPIDPPWPPGKPTVKDVGKTSVRLNWTKPEHDGGAKIESY-VIEMLKT 14025

Query: 1672  GPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQP-------LVQTAVTNID 1724
             G         G   T+  + GL    EY   V A N +GES+P       L +  +    
Sbjct: 14026 GTDEWVRVAEGVPTTQHLLPGLMEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPS 14085

Query: 1725  RPKGLAFTDVDVDSIKIAWESPQ----GQVSRYRVTYSSPEDGIHELFPAPDG--EEDTA 1778
              P+ L   ++  ++  + W  P+      ++ Y V      D   + +   D   ++   
Sbjct: 14086 PPRWLEVINITKNTADLKWTVPEKDGGSPITNYIV---EKRDVRRKGWQTVDTTVKDTKC 14142

Query: 1779  ELQGLRPGSEYTVSVVAL-------HDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSA 1831
              +  L  GS Y   V A        + ++E   L     T    P  L    VT   +  
Sbjct: 14143 TVTPLTEGSLYVFRVAAENAIGQSDYTEIEDSVLAKDTFTTPGPPYALAVVDVTKRHVDL 14202

Query: 1832  QWTPPNVQ--LTGYRVRVTPKEKTGP--MKEINLAPDSSSVVVSGLMVATKYEVSVYALK 1887
             +W PP         R  +  KE+ G   +K    A    +  V+ ++  T+ +  V A  
Sbjct: 14203 KWEPPKNDGGRPIQRYVIEKKERLGTRWVKAGKTAGPDCNFRVTDVIEGTEVQFQVRAEN 14262

Query: 1888  DTLTSRPAQGV-VTTLEN----VSPPRRARVTDATETTITISWRTKTET----ITGFQVD 1938
             +     P++   + ++E+     SPP    VTDA    I I+W+   +     I G+ V+
Sbjct: 14263 EAGVGHPSEPTEILSIEDPTSPPSPPLDLHVTDAGRKHIAIAWKPPEKNGGSPIIGYHVE 14322

Query: 1939  AVPANGQTPIQRTIKP--DVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDA 1996
               P   +  ++   +P  D++     G+ P  +Y + +  +N    S P  I  +     
Sbjct: 14323 MCPVGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAIGVSEPSEISENVVAKD 14382

Query: 1997  P 1997
             P
Sbjct: 14383 P 14383



 Score =  115 bits (288), Expect = 5e-25
 Identities = 291/1449 (20%), Positives = 530/1449 (36%), Gaps = 173/1449 (11%)

Query: 785   KYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPT-VDQVDDTSIVVRWSRPQ----APIT 839
             +Y++ +  ++  G +S+ ++      P  P  P  ++ +      + W RPQ    A I 
Sbjct: 25859 QYVLTLKNVA--GTRSVAVNCKVLDKPGPPAGPLEINGLTAEKCSLSWGRPQEDGGADID 25916

Query: 840   GYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETT 899
              Y +    +   + T         S  ++ L  G +Y   +  V +     P+    E+ 
Sbjct: 25917 YYIVEKRETSHLAWTICEGELQMTSCKVTKLLKGNEYIFRVTGVNKYGVGEPL----ESV 25972

Query: 900   GTPRSD--TVPSP-RDLQFVEVTDVKVTIMWTPPES----AVTGYRVDVIPVN-LPGEHG 951
                  D  TVPSP   L+   VT   +T+ W+ PES     ++GY ++    N L     
Sbjct: 25973 AIKALDPFTVPSPPTSLEITSVTKESMTLCWSRPESDGGSEISGYIIERREKNSLRWVRV 26032

Query: 952   QRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNL-------Q 1004
              + P+  +   + TGL  G  Y ++V+A +    S P       + + P  L       +
Sbjct: 26033 NKKPVY-DLRVKSTGLREGCEYEYRVYAENAAGLSLPSETSPLIRAEDPVFLPSPPSKPK 26091

Query: 1005  FVNETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPAS 1060
              V+   +T+ + W  P     A ITGY +    +     +        ++Y +  L   +
Sbjct: 26092 IVDSGKTTITIAWVKPLFDGGAPITGYTVEYKKSDDTDWKTSIQSLRGTEYTISGLTTGA 26151

Query: 1061  EYTVSLVAIK---GNQESPKATGVFTTLQPGSSIPPYNTEVTETTIV-----ITWT---- 1108
             EY   + ++     +  S  +       +    +   ++E+ +T IV      T T    
Sbjct: 26152 EYVFRVKSVNKVGASDPSDSSDPQIAKEREEEPLFDIDSEMRKTLIVKAGASFTMTVPFR 26211

Query: 1109  --PAPRIGFKLGVRPSQG--GEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDA 1164
               P P +   L  +P       A  + T    S+ +          YT+ +         
Sbjct: 26212 GRPVPNV---LWSKPDTDLRTRAYVDTTDSRTSLTIENANRNDSGKYTLTIQNVLSAASL 26268

Query: 1165  PIVNKVVTPLSPPTNLHLE-ANPDTGVLTVSW---ERSTTPDITGYRITTTPTNGQQGNS 1220
              +V KV+    PPTN+ ++    ++ VL  SW   E      +  Y I     + +   S
Sbjct: 26269 TLVVKVLDTPGPPTNITVQDVTKESAVL--SWDVPENDGGAPVKNYHIEKREASKKAWVS 26326

Query: 1221  LE--------EVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPEVPQLTD 1272
             +         +V +  + +  +  +S   E+ V +    + KE V I++   P  P+   
Sbjct: 26327 VTNNCNRLSYKVTNLQEGAIYYFRVSGENEFGVGIPA--ETKEGVKITEK--PSPPE--K 26380

Query: 1273  LSFVDITDSSIGLRWTPLN---SSTIIGYRITVVAAGEGIPIFEDFVDSSVG---YYTVT 1326
             L    I+  S+ L W        S I+ Y +  +  G+     +++V  +V    ++ V+
Sbjct: 26381 LGVTSISKDSVSLTWLKPEHDGGSRIVHYVVEALEKGQ-----KNWVKCAVAKSTHHVVS 26435

Query: 1327  GLEPGIDYDISVITLINGGESAPT-----TLTQQTAVPPPTDLRFTNIGPDTMRVTWAPP 1381
             GL    +Y   V      G S P       L ++   PP  D++  N    T+ V     
Sbjct: 26436 GLRENSEYFFRVFAENQAGLSDPRELLLPVLIKEQLEPPEIDMK--NFPSHTVYVRAGSN 26493

Query: 1382  PSIDLTNFLVRYSPVKNEEDVAELSISPSDNA-VVLTNLLPGTEYVVSVSSVYEQHESTP 1440
               +D+         V    D   L  +   N  +   NL    +  V+  +   +  +  
Sbjct: 26494 LKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADAGRYEITAAN 26553

Query: 1441  LRGRQKTGLD--------SPTG-IDFSDITANSFTVHWIAPR----ATITGYRIRHHPEH 1487
               G  K  ++         PTG +  SDIT  S T+ W  P+    + +T Y +    E 
Sbjct: 26554 SSGTTKAFINIVVLDRPGPPTGPVVISDITEESVTLKWEPPKYDGGSQVTNYILLKR-ET 26612

Query: 1488  FSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGR------EESPLLIGQQSTVSDV 1541
              +    E     +R  + +  LT G EY   I A N        + + + +    T    
Sbjct: 26613 STAVWTEVSATVARTMMKVMKLTTGEEYQFRIKAENRFGISDHIDSACVTVKLPYTTPGP 26672

Query: 1542  PRDLEVVAATPTSLLISWDAPAVT----VRYYRITYGETGGNSPVQEFTVPGSKSTATIS 1597
             P    V   T  S+ + W  P       V  Y +   +       +   +    +   ++
Sbjct: 26673 PSTPWVTNVTRESITVGWHEPVSNGGSAVVGYHLEMKDRNSILWQKANKLVIRTTHFKVT 26732

Query: 1598  GLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKW---- 1653
              +  G+ Y   VYA    G    S     +      + P  +++TD+  NS+S+ W    
Sbjct: 26733 TISAGLIYEFRVYAENAAGVGKPSHPSEPVLAIDACEPPRNVRITDISKNSVSLSWQQPA 26792

Query: 1654  LPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE-S 1712
                 S +TGY V          TK       +T+  I GL    +Y   V+A+N  G  S
Sbjct: 26793 FDGGSKITGYIVERRDLPDGRWTKASFTNVTETQFIISGLTQNSQYEFRVFARNAVGSIS 26852

Query: 1713  QPL-VQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAP 1771
              P  V   +T ID   G    D+ ++  ++  +   G   + R   S       E +   
Sbjct: 26853 NPSEVVGPITCIDSYGGPVI-DLPLEYTEVV-KYRAGTSVKLRAGISGKPAPTIEWYK-D 26909

Query: 1772  DGEEDTAELQGLRPGSEYTVSVVALHDDMES-------QPLIGTQSTAI---------PA 1815
             D E  T  L  +   ++    ++   D + S       +  +G+ S  I         P 
Sbjct: 26910 DKELQTNALVCVENTTDLASILIKDADRLNSGCYELKLRNAMGSASATIRVQILDKPGPP 26969

Query: 1816  PTDLKFTQVTPTSLSAQWTPP----NVQLTGYRVRVTPKEKTGPM--KEINLAPDSSSVV 1869
                ++F  VT   ++  W PP      ++T Y   +  K +T  +    ++   +   + 
Sbjct: 26970 GGPIEFKTVTAEKITLLWRPPADDGGAKITHY---IVEKRETSRVVWSMVSEHLEECIIT 27026

Query: 1870  VSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENV----SPPRRARVTDATETTITISW 1925
              + ++   +Y   V A+       P +      +N      PP    VT  T+ ++T+ W
Sbjct: 27027 TTKIIKGNEYIFRVRAVNKYGIGEPLESDSVVAKNAFVTPGPPGIPEVTKITKNSMTVVW 27086

Query: 1926  RTKT----ETITGFQV---DAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLN 1978
                       I+G+ +   D         ++ TI+ D R   +TGL   +DY+  +  +N
Sbjct: 27087 SRPIADGGSDISGYFLEKRDKKSLGWFKVLKETIR-DTRQ-KVTGLTENSDYQYRVCAVN 27144

Query: 1979  DNAR---SSPVVI-DASTAIDAP---SNLRFLATTPNSLLVSWQPP----RARITGYIIK 2027
                +   S P     A+  ID P   + +R   +T +S+ + W  P     + +TGY+++
Sbjct: 27145 AAGQGPFSEPSEFYKAADPIDPPGPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVVE 27204

Query: 2028  YEKPGSPPREVVP-RPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQKT 2086
               +        V  +     TE  ++ L+PG  Y   V A+    + EP I   + VQ  
Sbjct: 27205 IRQGEEEEWTTVSTKGEVRTTEYVVSNLKPGVNYYFRVSAVNCAGQGEP-IEMNEPVQAK 27263

Query: 2087  PFVTHPGYD 2095
               +  P  D
Sbjct: 27264 DILEAPEID 27272



 Score =  115 bits (287), Expect = 7e-25
 Identities = 310/1519 (20%), Positives = 528/1519 (34%), Gaps = 242/1519 (15%)

Query: 758   EEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLI---LSTSQTTAPDAP 814
             E GD  +   L + A  V    + P  +    +Y +  +     I   +  +    P AP
Sbjct: 13436 ETGDRVKMKTLSAYAELV----ISPSERSDKGIYTLKLENRVKTISGEIDVNVIARPSAP 13491

Query: 815   PDPTVDQVDDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTLSDL 870
              +     +   S+ + W  P     +P+TGY +        + T++    T    T+ DL
Sbjct: 13492 KELKFGDITKDSVHLTWEPPDDDGGSPLTGYVVEKREVSRKTWTKVMDFVTDLEFTVPDL 13551

Query: 871   QPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP 930
               G +Y   + A  +     P  + +    +  +     P ++++ + T   + + W PP
Sbjct: 13552 VQGKEYLFKVCARNKCGPGEPAYVDEPVNMSTPATVPDPPENVKWRDRTANSIFLTWDPP 13611

Query: 931   E----SAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRES 986
             +    S + GY V+  P           P++  T  EVTGL  G  Y ++V A++    S
Sbjct: 13612 KNDGGSRIKGYIVERCPRGSDKWVACGEPVA-ETKMEVTGLEEGKWYAYRVKALNRQGAS 13670

Query: 987   KP---------------------------LTAQQTTKLDAPTNLQFVNETDSTVLVRWTP 1019
             KP                           LT +  TK++ P  +    E   T    WT 
Sbjct: 13671 KPSRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKIT----WT- 13725

Query: 1020  PRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKAT 1079
              +A +   +    +T    P++  V    SK           Y +  V + G   +    
Sbjct: 13726 -KADMI-LKQDKRITIENVPKKSTVTIVDSK-----RSDTGTYIIEAVNVCGRATAVVEV 13778

Query: 1080  GVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRI--GFKLGVRPSQGGEAPREVTSDSGS 1137
              V    +PG       T+VT  + ++TW P PR   G K+     +      EV     S
Sbjct: 13779 NVLD--KPGPPAAFDITDVTNESCLLTWNP-PRDDGGSKITNYVVERRATDSEVWHKLSS 13835

Query: 1138  IV------VSGLTPGVEYVYTI---QVLRDGQERDA-PIVNKV-VTPLSPPTNLHLEANP 1186
              V       + L P  EY++ +    +   G+   A PI  K    P  PPT L   ++ 
Sbjct: 13836 TVKDTNFKATKLIPNKEYIFRVAAENMYGVGEPVQASPITAKYQFDPPGPPTRLE-PSDI 13894

Query: 1187  DTGVLTVSW---ERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEY 1243
                 +T++W   +      ITGY +     +  +     ++   D ++     L+   +Y
Sbjct: 13895 TKDAVTLTWCEPDDDGGSPITGYWVERLDPDTDKWVRCNKMPVKD-TTYRVKGLTNKKKY 13953

Query: 1244  NVSVYTV------KDDKESVP--ISDTIIPEVPQLTDLSFVDITDSSIGLRWTPL---NS 1292
                V         K  K + P  I D I P  P     +  D+  +S+ L WT       
Sbjct: 13954 RFRVLAENLAGPGKPSKSTEPILIKDPIDPPWPP-GKPTVKDVGKTSVRLNWTKPEHDGG 14012

Query: 1293  STIIGYRITVVAAG--------EGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLING 1344
             + I  Y I ++  G        EG+P  +         + + GL  G +Y   V  +   
Sbjct: 14013 AKIESYVIEMLKTGTDEWVRVAEGVPTTQ---------HLLPGLMEGQEYSFRVRAVNKA 14063

Query: 1345  GESAPT-----TLTQQTAVP--PPTDLRFTNIGPDTMRVTWAPPP---SIDLTNFLVRYS 1394
             GES P+      L ++   P  PP  L   NI  +T  + W  P       +TN++V   
Sbjct: 14064 GESEPSEPSDPVLCREKLYPPSPPRWLEVINITKNTADLKWTVPEKDGGSPITNYIVEKR 14123

Query: 1395  PVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVS-------SVYEQHESTPLRGRQKT 1447
              V+  +    +  +  D    +T L  G+ YV  V+       S Y + E + L     T
Sbjct: 14124 DVR-RKGWQTVDTTVKDTKCTVTPLTEGSLYVFRVAAENAIGQSDYTEIEDSVLAKDTFT 14182

Query: 1448  GLDSPTGIDFSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRNS 1503
                 P  +   D+T     + W  P+      I  Y I       +   +  +      +
Sbjct: 14183 TPGPPYALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKERLGTRWVKAGKTAGPDCN 14242

Query: 1504  ITLTNLTPGTEYVVSIVALN----GREESP---LLIGQQSTVSDVPRDLEVVAATPTSLL 1556
               +T++  GTE    + A N    G    P   L I   ++    P DL V  A    + 
Sbjct: 14243 FRVTDVIEGTEVQFQVRAENEAGVGHPSEPTEILSIEDPTSPPSPPLDLHVTDAGRKHIA 14302

Query: 1557  ISWDAPAVTVRYYRITYGETGGNSPVQEFTVP----GSKSTATIS-------------GL 1599
             I+W  P            E  G SP+  + V     G++    ++             G+
Sbjct: 14303 IAWKPP------------EKNGGSPIIGYHVEMCPVGTEKWMRVNSRPIKDLKFKVEEGV 14350

Query: 1600  KPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSP 1659
              P  +Y + V AV   G     S+P  I+       P      D++ + I V      S 
Sbjct: 14351 VPDKEYVLRVRAVNAIG----VSEPSEISENVVAKDPDCKPTIDLETHDIIVIEGEKLSI 14406

Query: 1660  VTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYA---------QNPSG 1710
                +R    P         +    D+  M  + +   +E   SV A         +N  G
Sbjct: 14407 PVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLG 14466

Query: 1711  ESQPLVQTAVTNIDRP-KGLAFTDVDVDSIKIAWESPQ--GQVSRYRVTYSSPEDGIHEL 1767
              +   +   V  +  P K +  +D+   S K+ WE P+  G            E G    
Sbjct: 14467 SATASINVKVIGLPGPCKDIKASDITKSSCKLTWEPPEFDGGTPILHYVLERREAGRRTY 14526

Query: 1768  FPAPDGEEDTA-ELQGLRPGSEYTVSVVALH-----DDME-SQPLIGTQSTAIP-APTDL 1819
              P   GE   +  ++ L P  EY   V A++     + +E   P+I       P  P D+
Sbjct: 14527 IPVMSGENKLSWTVKDLIPNGEYFFRVKAVNKVGGGEYIELKNPVIAQDPKQPPDPPVDV 14586

Query: 1820  KFTQVTPTSLSAQWTPP----NVQLTGYRV-RVTPKEKTGPMKEINLAPDSSSVVVSGLM 1874
             +    T  +++  W PP      ++ GY + ++   E+       +L P   +    GL 
Sbjct: 14587 EVHNPTAEAMTITWKPPLYDGGSKIMGYIIEKIAKGEERWKRCNEHLVP-ILTYTAKGLE 14645

Query: 1875  VATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTI------------- 1921
                +Y+  V A      S P++    T + V P    +V   T   +             
Sbjct: 14646 EGKEYQFRVRAENAAGISEPSRATPPT-KAVDPIDAPKVILRTSLEVKRGDEIALDASIS 14704

Query: 1922  -----TISWRTKTETITGFQVD--------------------AVPANGQTPIQRTIKPDV 1956
                  TI+W      I   ++                      +P   +  I  + K + 
Sbjct: 14705 GSPYPTITWIKDENVIVPEEIKKRAAPLVRRRKGEVQEEEPFVLPLTQRLSIDNSKKGES 14764

Query: 1957  RSYTITGLQPGTDYKIYLYTL-NDNA-RSSPVVIDASTAIDAPSNLRFLATTPNSLLVSW 2014
             +      L+P  D+ +Y+  + ND+    +P  +        P N  F      S+L  W
Sbjct: 14765 QLRVRDSLRP--DHGLYMIKVENDHGIAKAPCTVSVLDTPGPPINFVFEDIRKTSVLCKW 14822

Query: 2015  QPP----RARITGYIIKYEKPGSPPRE-VVPRPRPGVTEATITGLEPGTEYTIYVIALKN 2069
             +PP     + I  Y ++ +    P  E +V        + ++T L  G EY ++ +  +N
Sbjct: 14823 EPPLDDGGSEIINYTLEKKDKTKPDSEWIVVTSTLRHCKYSVTKLIEGKEY-LFRVRAEN 14881

Query: 2070  NQKSEPLIGRKKTVQKTPF 2088
                  P    K  V K PF
Sbjct: 14882 RFGPGPPCVSKPLVAKDPF 14900



 Score =  114 bits (286), Expect = 9e-25
 Identities = 280/1356 (20%), Positives = 495/1356 (36%), Gaps = 217/1356 (16%)

Query: 727   SVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQ--YLDLPSTA--TSVNIPDLLP 782
             +VTE+T+   V+SW    D   G ++++ + ++ +  +  + ++ S    T + +  LL 
Sbjct: 21563 AVTEVTSEKCVLSWFPPLDD-GGAKIDHYIVQKRETSRLAWTNVASEVQVTKLKVTKLLK 21621

Query: 783   GRKYI-----VNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAP 837
             G +YI     VN Y + E  E   +L+ +    PD P +P V  +   S+VV W  P + 
Sbjct: 21622 GNEYIFRVMAVNKYGVGEPLESEPVLAVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDS- 21680

Query: 838   ITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQ-------PGVQYNITIYAVEENQEST 890
               G   + +  VE            N  TL+DL+        G +Y   I A      S 
Sbjct: 21681 -DGGSEIINYIVERRDKAGQRWIKCNKKTLTDLRYKVSGLTEGHEYEFRIMAENAAGISA 21739

Query: 891   PVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNL 946
             P                  P + + ++ +   ++I W  P     S +TGY V++    L
Sbjct: 21740 PSPTSPFYKACDTVFKPGPPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIA---L 21796

Query: 947   PGEHGQRLPIS----RNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLD---A 999
             P E   ++       + T   +TGL+    Y  +++A++     +P     T K +    
Sbjct: 21797 PEEDEWQIVTPPAGLKATSYTITGLTENQEYKIRIYAMNSEGLGEPALVPGTPKAEDRML 21856

Query: 1000  PTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPR---QYNVGPSVSKYPLRNL 1056
             P  ++   +    V +R           RL V +  R  P      + G S+ K    ++
Sbjct: 21857 PPEIELDADLRKVVTIR------ACCTLRLFVPIKGRPAPEVKWARDHGESLDK---ASI 21907

Query: 1057  QPASEYTVSLVAIKGNQESPK----------ATGVFTTLQ----PGSSIPPYNTEVTETT 1102
             +  S YT+ +V      +S K          +   F  ++    PG        EVT+T+
Sbjct: 21908 ESTSSYTLLIVGNVNRFDSGKYILTVENSSGSKSAFVNVRVLDTPGPPQDLKVKEVTKTS 21967

Query: 1103  IVITWTPAPRI--GFKLGVRPSQGGEAPREVTS------DSGSIVVSGLTPGVEYVYTIQ 1154
             + +TW P P +  G K+     +  E+ R+  S         S  V  L  G  Y +  +
Sbjct: 21968 VTLTWDP-PLLDGGSKIKNYIVEKRESTRKAYSTVATNCHKTSWKVDQLQEGCSYYF--R 22024

Query: 1155  VLRDGQ------ERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPD---ITG 1205
             VL + +         A  V     PL P     ++   ++  +++SWE+        I G
Sbjct: 22025 VLAENEYGIGLPAETAESVKASERPLPPGKITLMDVTRNS--VSLSWEKPEHDGGSRILG 22082

Query: 1206  YRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYT-----VKDDKE-SVPI 1259
             Y I    T G    +    V   +++ T   L  G EY+  V       + D ++ SVP+
Sbjct: 22083 Y-IVEMQTKGSDKWATCATVKVTEATIT--GLIQGEEYSFRVSAQNEKGISDPRQLSVPV 22139

Query: 1260  --SDTIIPEVPQLTDLSFVDITDSSI------------GLRW----TPLNSSTIIGYRIT 1301
                D +IP   +L   +F  +    +             + W     PL  +T +    T
Sbjct: 22140 IAKDLVIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAEST 22199

Query: 1302  VVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTL---TQQTAV 1358
                    +   +D     VG+Y              V+ L N    A  TL         
Sbjct: 22200 ---ENNSLLTIKDACREDVGHY--------------VVKLTNSAGEAIETLNVIVLDKPG 22242

Query: 1359  PPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAE---LSISPSDNAVV 1415
             PP   ++   +  D++ ++W  PP  D  + +  Y   K +        +S + +   + 
Sbjct: 22243 PPTGPVKMDEVTADSITLSWG-PPKYDGGSSINNYIVEKRDTSTTTWQIVSATVARTTIK 22301

Query: 1416  LTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTG-----LDSPTGIDFSDITA-NSFTVHW 1469
                L  G EY   +++     +ST L            +  P G     +++ +S  V W
Sbjct: 22302 ACRLKTGCEYQFRIAAENRYGKSTYLNSEPTVAQYPFKVPGPPGTPVVTLSSRDSMEVQW 22361

Query: 1470  IAP----RATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGR 1525
               P     + + GY +     +     + ++ P  +     T L  G EY   + A    
Sbjct: 22362 NEPISDGGSRVIGYHLERKERNSILWVKLNKTPIPQTKFKTTGLEEGVEYEFRVSA---- 22417

Query: 1526  EESPLLIGQQSTVSD--VPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQ 1583
              E+ + IG+ S VS+  V RD       P +++++ +  +VT+++ + TY    G S + 
Sbjct: 22418 -ENIVGIGKPSKVSECYVARDPCDPPGRPEAIIVTRN--SVTLQWKKPTY---DGGSKIT 22471

Query: 1584  EFTVPGS--------KSTAT--------ISGLKPGVDYTITVYAVTGRG-DSPASSKPIS 1626
              + V           K++ T        ++GL     Y   V A    G  S  S    +
Sbjct: 22472 GYIVEKKELPEGRWMKASFTNIIDTHFEVTGLVEDHRYEFRVIARNAAGVFSEPSESTGA 22531

Query: 1627  INYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQT 1686
             I  R E+D P        +D  +             ++V       P PT     G  + 
Sbjct: 22532 ITARDEVDPPRISMDPKYKDTIV-------VHAGESFKVDADIYGKPIPTIQWIKGDQEL 22584

Query: 1687  EMTIEGLQPTVEYVVS---------------VYAQNPSGESQPLVQTAVTNIDRP----K 1727
               T      + ++  S               + A+N +GE    V   V  +DRP     
Sbjct: 22585 SNTARLEIKSTDFATSLSVKDAVRVDSGNYILKAKNVAGERSVTVNVKV--LDRPGPPEG 22642

Query: 1728  GLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHEL-FPAPDGEEDT--AELQGLR 1784
              +  + V  +   +AW+ P        + Y         L +   D    T   ++  L 
Sbjct: 22643 PVVISGVTAEKCTLAWKPPLQDGGSDIINYIVERRETSRLVWTVVDANVQTLSCKVTKLL 22702

Query: 1785  PGSEYTVSVVALH-----DDMESQPLIGTQSTAIP-APTDLKFTQVTPTSLSAQWTPP-- 1836
              G+EYT  ++A++     + +ES+P++      +P AP   + T VT  S+   W  P  
Sbjct: 22703 EGNEYTFRIMAVNKYGVGEPLESEPVVAKNPFVVPDAPKAPEVTTVTKDSMIVVWERPAS 22762

Query: 1837  --NVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRP 1894
                 ++ GY +    KE     +          + V+GL+    YE  V A      S P
Sbjct: 22763 DGGSEILGYVLEKRDKEGIRWTRCHKRLIGELRLRVTGLIENHDYEFRVSAENAAGLSEP 22822

Query: 1895  A-----QGVVTTLENVSPPRRARVTDATETTITISW 1925
             +     Q     +    PP   +V D T +++ +SW
Sbjct: 22823 SPPSAYQKACDPIYKPGPPNNPKVIDITRSSVFLSW 22858



 Score =  114 bits (285), Expect = 1e-24
 Identities = 294/1413 (20%), Positives = 501/1413 (35%), Gaps = 193/1413 (13%)

Query: 806   SQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ----APITGYRIVYSPSVEGS-STELNLPE 860
             S+   P  P + T+  V+   + + W  P+    A IT Y I           T + +  
Sbjct: 13186 SKYDVPGPPLNVTITDVNRFGVSLTWEPPEYDGGAEITNYVIELRDKTSIRWDTAMTVRA 13245

Query: 861   TANSVTLSDLQPGVQYNITIYA-----VEENQESTPVVIQQETTGTPRSDTVPSPRDLQF 915
                S T++D+  G +Y+  + A     V +   +TP V   +    P       P +L  
Sbjct: 13246 EDLSATVTDVVEGQEYSFRVRAQNRIGVGKPSAATPFVKVADPIERPSP-----PVNLTS 13300

Query: 916   VEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGV 971
              + T   V + W PP     S + GY ++             + +      +VTGL  G 
Sbjct: 13301 SDQTQSSVQLKWEPPLKDGGSPILGYIIERCEEGKDNWIRCNMKLVPELTYKVTGLEKGN 13360

Query: 972   TYYFKVFAVSHGRESKP------LTA-----QQTTKLDA-PTNLQFVNETDSTVLVRWTP 1019
              Y ++V A +    S P      LTA     + T  L A    L+ +     T+LV  T 
Sbjct: 13361 KYLYRVSAENKAGVSDPSEILGPLTADDAFVEPTMDLSAFKDGLEVIVPNPITILVPSTG 13420

Query: 1020  -PRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKA 1078
              PR   T       L    + +      ++S Y    + P+      +  +K        
Sbjct: 13421 YPRPTATWCFGDKVLETGDRVKM----KTLSAYAELVISPSERSDKGIYTLKLENRVKTI 13476

Query: 1079  TG---VFTTLQPGSSIPPYNTEVTETTIVITWTP------APRIGFKLGVRPSQGGEAPR 1129
             +G   V    +P +       ++T+ ++ +TW P      +P  G+ +  R     E  R
Sbjct: 13477 SGEIDVNVIARPSAPKELKFGDITKDSVHLTWEPPDDDGGSPLTGYVVEKR-----EVSR 13531

Query: 1130  EVTSDSGSIV------VSGLTPGVEYVYTIQVLRDGQERDAPIVNKVV---TPLS---PP 1177
             +  +     V      V  L  G EY++ +         +   V++ V   TP +   PP
Sbjct: 13532 KTWTKVMDFVTDLEFTVPDLVQGKEYLFKVCARNKCGPGEPAYVDEPVNMSTPATVPDPP 13591

Query: 1178  TNLHLEANPDTGVLTVSWERSTTPD---ITGYRITTTPTNGQQGNSLEEVVHADQSSCTF 1234
              N+         +  ++W+         I GY +   P    +  +  E V   +   T 
Sbjct: 13592 ENVKWRDRTANSIF-LTWDPPKNDGGSRIKGYIVERCPRGSDKWVACGEPVAETKMEVT- 13649

Query: 1235  DNLSPGLEYNVSVYTVKDDKESVPISDT-------------IIPEVPQLTDLSF-----V 1276
               L  G  Y   V  +     S P   T             I  +V  L  L+      +
Sbjct: 13650 -GLEEGKWYAYRVKALNRQGASKPSRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKI 13708

Query: 1277  DITDSSIG-----LRWTPLNSSTIIGYRITVVAAGEGIP-----IFEDFVDSSVGYYTVT 1326
             ++  +  G     + WT  +       RIT+    E +P        D   S  G Y + 
Sbjct: 13709 ELPATVTGKPEPKITWTKADMILKQDKRITI----ENVPKKSTVTIVDSKRSDTGTYIIE 13764

Query: 1327  GLEPGIDYDISVITLINGGESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAPPPS--- 1383
              +             + G  +A   +       PP     T++  ++  +TW PP     
Sbjct: 13765 AVN------------VCGRATAVVEVNVLDKPGPPAAFDITDVTNESCLLTWNPPRDDGG 13812

Query: 1384  IDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSS-----VYEQHES 1438
               +TN++V      +E    +LS +  D     T L+P  EY+  V++     V E  ++
Sbjct: 13813 SKITNYVVERRATDSEV-WHKLSSTVKDTNFKATKLIPNKEYIFRVAAENMYGVGEPVQA 13871

Query: 1439  TPLRGR-QKTGLDSPTGIDFSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPR 1493
             +P+  + Q      PT ++ SDIT ++ T+ W  P     + ITGY +           R
Sbjct: 13872 SPITAKYQFDPPGPPTRLEPSDITKDAVTLTWCEPDDDGGSPITGYWVERLDPDTDKWVR 13931

Query: 1494  EDRVPHSRNSITLTNLTPGTEYVVSIVALN-------GREESPLLIGQQSTVSDVPRDLE 1546
              +++P    +  +  LT   +Y   ++A N        +   P+LI         P    
Sbjct: 13932 CNKMPVKDTTYRVKGLTNKKKYRFRVLAENLAGPGKPSKSTEPILIKDPIDPPWPPGKPT 13991

Query: 1547  VVAATPTSLLISWDAP----AVTVRYYRITYGETGGNSPVQEFTVPGSKSTA-TISGLKP 1601
             V     TS+ ++W  P       +  Y I   +TG +  V+     G  +T   + GL  
Sbjct: 13992 VKDVGKTSVRLNWTKPEHDGGAKIESYVIEMLKTGTDEWVR--VAEGVPTTQHLLPGLME 14049

Query: 1602  GVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQ---MQVTDVQDNSISVKWL---- 1654
             G +Y+  V AV   G+S  S     +  R ++  PS    ++V ++  N+  +KW     
Sbjct: 14050 GQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLEVINITKNTADLKWTVPEK 14109

Query: 1655  PSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQ- 1713
                SP+T Y V        G     T   D T+ T+  L     YV  V A+N  G+S  
Sbjct: 14110 DGGSPITNYIVEKRDVRRKGWQTVDTTVKD-TKCTVTPLTEGSLYVFRVAAENAIGQSDY 14168

Query: 1714  ------PLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQ----VSRYRVTYSSPEDG 1763
                    L +   T    P  LA  DV    + + WE P+      + RY +        
Sbjct: 14169 TEIEDSVLAKDTFTTPGPPYALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKERLGT 14228

Query: 1764  IHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPT------ 1817
                      G +    +  +  G+E    V A ++     P   T+  +I  PT      
Sbjct: 14229 RWVKAGKTAGPDCNFRVTDVIEGTEVQFQVRAENEAGVGHPSEPTEILSIEDPTSPPSPP 14288

Query: 1818  -DLKFTQVTPTSLSAQWTPPNVQ----LTGYRVRVTPKEKTGPMKEINLAP--DSSSVVV 1870
              DL  T      ++  W PP       + GY V + P   T     +N  P  D    V 
Sbjct: 14289 LDLHVTDAGRKHIAIAWKPPEKNGGSPIIGYHVEMCP-VGTEKWMRVNSRPIKDLKFKVE 14347

Query: 1871  SGLMVATKYEVSVYALKDTLTSRP---AQGVVTTLENVSP-----PRRARVTDATETTIT 1922
              G++   +Y + V A+     S P   ++ VV    +  P          V +  + +I 
Sbjct: 14348 EGVVPDKEYVLRVRAVNAIGVSEPSEISENVVAKDPDCKPTIDLETHDIIVIEGEKLSIP 14407

Query: 1923  ISWRTKTETITGFQVDAVPANGQTPIQRTIKPD-VRSYTITGLQPGTDYKIYLYTLNDNA 1981
             + +R        +  D         +  T+K D + ++         D  IY  TL +  
Sbjct: 14408 VPFRAVPVPTVSWHKDGKEVKASDRL--TMKNDHISAHLEVPKSVRADAGIYTITLENKL 14465

Query: 1982  RSSPVVIDAST-AIDAP-SNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPP 2035
              S+   I+     +  P  +++    T +S  ++W+PP       I  Y+++  + G   
Sbjct: 14466 GSATASINVKVIGLPGPCKDIKASDITKSSCKLTWEPPEFDGGTPILHYVLERREAGR-- 14523

Query: 2036  REVVP-RPRPGVTEATITGLEPGTEYTIYVIAL 2067
             R  +P          T+  L P  EY   V A+
Sbjct: 14524 RTYIPVMSGENKLSWTVKDLIPNGEYFFRVKAV 14556



 Score =  112 bits (281), Expect = 3e-24
 Identities = 353/1634 (21%), Positives = 588/1634 (35%), Gaps = 247/1634 (15%)

Query: 607   SSSGPVEVFIT----ETPSQPNSHPIQWNAPQPSHISKYILRWRP---------KNSVGR 653
             +SSG    F+T    +TP  P +  ++      +      L W P         KN V  
Sbjct: 24099 NSSGSKSAFVTVKVLDTPGPPQNLAVKEVRKDSA-----FLVWEPPIIDGGAKVKNYVID 24153

Query: 654   WKEATIPGHLN--------SYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTP 705
              +E+T   + N        S+ ++ L  G +Y  ++++  ++G                P
Sbjct: 24154 KRESTRKAYANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFG-------------VGVP 24200

Query: 706   VTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVS----ASDTVSGFRVEYELSEEGD 761
             V +        P SP      ++T+++ +S  + W          V G+ VE  +  +G 
Sbjct: 24201 VETVDAVKAAEPPSP--PGKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVE--MQPKGT 24256

Query: 762   EPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQ 821
             E   +   S   +  +  L  G++Y   V   +E G+    +      A D    P++  
Sbjct: 24257 EKWSIVAESKVCNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKL 24316

Query: 822   VDDTSIVVRWS--RPQAPITGY-RIVYSPSVEGS----STELNLPETANSVTLSDLQPGV 874
               +T  +      + + P+ G  R   S   +G     +T +N+ ETA S  L  ++ G 
Sbjct: 24317 PFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLH-IKEGN 24375

Query: 875   QYNITIYAVEENQESTPV-----VIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTP 929
             + +   Y V     +        VI  E  G P          ++F EV+   V I W P
Sbjct: 24376 KDDFGKYTVTATNSAGTATENLSVIVLEKPGPPVGP-------VRFDEVSADFVVISWEP 24428

Query: 930   PESA----VTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRE 985
             P       ++ Y V+         H     ++R T  ++T L  G  Y F++FA +   +
Sbjct: 24429 PAYTGGCQISNYIVEKRDTTTTTWHMVSATVARTTI-KITKLKTGTEYQFRIFAENRYGK 24487

Query: 986   SKPLTA-----QQTTKLDAPTNLQFVNE-TDSTVLVRWTPP----RAQITGYRLTVGLTR 1035
             S PL +     Q   K   P    FV   +   +LV+W  P      +I GY L      
Sbjct: 24488 SAPLDSKAVIVQYPFKEPGPPGTPFVTSISKDQMLVQWHEPVNDGGTKIIGYHLEQKEKN 24547

Query: 1036  RGQPRQYNVGP-SVSKYPLRNLQPASEY--TVSLVAIKGNQESPKATGVFTTLQPGSSIP 1092
                  + N  P   +K+    L    EY   VS   I G  +  K +  F    P    P
Sbjct: 24548 SILWVKLNKTPIQDTKFKTTGLDEGLEYEFKVSAENIVGIGKPSKVSECFVARDPCD--P 24605

Query: 1093  PYNTE---VTETTIVITW-TPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVE 1148
             P   E   +T   + + W  PA   G K+       G    +     G  + +  T  +E
Sbjct: 24606 PGRPEAIVITRNNVTLKWKKPAYDGGSKI------TGYIVEKKDLPDGRWMKASFTNVLE 24659

Query: 1149  YVYTIQVLRDGQERDAPIV-NKVVTPLSPPT---------------NLHLEAN-PDTGVL 1191
               +T+  L + Q  +  ++        S P+               N  L+    D  V+
Sbjct: 24660 TEFTVSGLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARDEIDAPNASLDPKYKDVIVV 24719

Query: 1192  TVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNL---------SPGLE 1242
                       DI G  I     + + G  LEE     +   T             + G +
Sbjct: 24720 HAGETFVLEADIRGKPIPDVVWS-KDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQ 24778

Query: 1243  YNVSVYTVKDDKESVPISDTIIPEV-PQLTDLSFVDITDSSIGLRWTP--LNSSTIIGYR 1299
             Y + +  V   K S+PI+  ++    P    L    +T     L W P   +    I + 
Sbjct: 24779 YILKLSNVGGTK-SIPITVKVLDRPGPPEGPLKVTGVTAEKCYLAWNPPLQDGGANISHY 24837

Query: 1300  ITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGG-----ESAPTTLTQ 1354
             I        +   +   +     Y VT L PG +Y   V+ +   G     ES P T   
Sbjct: 24838 IIEKRETSRLSWTQVSTEVQALNYKVTKLLPGNEYIFRVMAVNKYGIGEPLESGPVTACN 24897

Query: 1355  QTAVP-PPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISP---S 1410
                 P PP+    + I  D+M VTWA P     T         +++E V     +    +
Sbjct: 24898 PYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDKEGVRWTKCNKKTLT 24957

Query: 1411  DNAVVLTNLLPGTEYVVSVSS-----VYEQHESTPLRGRQKTGL---DSPTGIDFSDITA 1462
             D  + +T L  G  Y   V++     V E  E +    R    L     P+    +D + 
Sbjct: 24958 DLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFY-RACDALYPPGPPSNPKVTDTSR 25016

Query: 1463  NSFTVHWIAP----RATITGYRIRHHPEHFSGRPREDRVPHS---RNSITLTNLTPGTEY 1515
             +S ++ W  P     A + GY +    +  +        P +       T+T L   TEY
Sbjct: 25017 SSVSLAWSKPIYDGGAPVKGYVV--EVKEAAADEWTTCTPPTGLQGKQFTVTKLKENTEY 25074

Query: 1516  VVSIVALN--GREESPLLIGQQSTVSDV-PRDLEVVAATPTSLLISWDAPAVTVRYYRIT 1572
                I A+N  G  E   L G       + P ++E+ A     +++   A   T+R +   
Sbjct: 25075 NFRICAINSEGVGEPATLPGSVVAQERIEPPEIELDADLRKVVVLRASA---TLRLFVTI 25131

Query: 1573  YGETGGNSPVQEFTVPGSKSTAT-ISGLKPGVDYTITVYAVTGRGDS---------PASS 1622
              G      P  E     ++   T  + ++    +T+ V     R DS          + S
Sbjct: 25132 KGR-----PEPEVKWEKAEGILTDRAQIEVTSSFTMLVIDNVTRFDSGRYNLTLENNSGS 25186

Query: 1623  KPISINYRTEIDKPS---QMQVTDVQDNSISVKWLP----SSSPVTGYRV---TTTPKNG 1672
             K   +N R  +D PS    + + +V+ +S+++ W P      + +T Y V    TT K  
Sbjct: 25187 KTAFVNVRV-LDSPSAPVNLTIREVKKDSVTLSWEPPLIDGGAKITNYIVEKRETTRK-- 25243

Query: 1673  PGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPK----G 1728
                  T T    +T   IE LQ    Y   V A N  G   P   T    +  P      
Sbjct: 25244 --AYATITNNCTKTTFRIENLQEGCSYYFRVLASNEYGIGLPAETTEPVKVSEPPLPPGR 25301

Query: 1729  LAFTDVDVDSIKIAWESPQ----GQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLR 1784
             +   DV  ++  I WE P+     +++ Y V   +   G  +       +   A + GL 
Sbjct: 25302 VTLVDVTRNTATIKWEKPESDGGSKITGYVVEMQT--KGSEKWSTCTQVKTLEATISGLT 25359

Query: 1785  PGSEYTVSVVALHDDMESQPL-----IGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQ 1839
              G EY   V A+++   S P      +  +   I    +L F   T    + +    +V 
Sbjct: 25360 AGEEYVFRVAAVNEKGRSDPRQLGVPVIARDIEIKPSVELPFH--TFNVKAREQLKIDVP 25417

Query: 1840  LTGYRVRVTPKEKTG-PMKEINLAPDSSSVVVSGLMV--ATKYEVSVYAL--KDTLTSRP 1894
               G         K G  +KE      SSS  V+ L +  A+K +V  Y L   ++  S  
Sbjct: 25418 FKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSNSAGSIT 25477

Query: 1895  AQGVVTTLENVSPPRRARVTDATETTITISWRTKTE----TITGFQVDAVPANGQT---- 1946
                 +  L+   PP   R+ + +  +ITISW          I+ + V+       T    
Sbjct: 25478 VPITIIVLDRPGPPGPIRIDEVSCDSITISWNPPEYDGGCQISNYIVEKKETTSTTWHIV 25537

Query: 1947  --PIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDA-------- 1996
                + RT      S  I  L  G++Y+  +   N   +SS      S+A+ A        
Sbjct: 25538 SQAVART------SIKIVRLTTGSEYQFRVCAENRYGKSS---YSESSAVVAEYPFSPPG 25588

Query: 1997  -PSNLRFLATTPNSLLVSWQPP----RARITGYIIKYEKPGSPPREVVPRPRPGVTEATI 2051
              P   + +  T +++LV+WQ P     +R+ GY ++Y++  S       +     T+  +
Sbjct: 25589 PPGTPKVVHATKSTMLVTWQVPVNDGGSRVIGYHLEYKERSSILWSKANKILIADTQMKV 25648

Query: 2052  TGLEPGT--EYTIY 2063
             +GL+ G   EY +Y
Sbjct: 25649 SGLDEGLMYEYRVY 25662



 Score =  109 bits (273), Expect = 3e-23
 Identities = 290/1404 (20%), Positives = 524/1404 (37%), Gaps = 190/1404 (13%)

Query: 812   DAPPDPT----VDQVDDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETAN 863
             D P  PT    +  + + S+ ++W  P+    + +T Y ++   +     TE++      
Sbjct: 26568 DRPGPPTGPVVISDITEESVTLKWEPPKYDGGSQVTNYILLKRETSTAVWTEVSATVART 26627

Query: 864   SVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFV-EVTDVK 922
              + +  L  G +Y   I A  EN+      I           T P P    +V  VT   
Sbjct: 26628 MMKVMKLTTGEEYQFRIKA--ENRFGISDHIDSACVTVKLPYTTPGPPSTPWVTNVTRES 26685

Query: 923   VTIMWTPPES----AVTGYRVDVIPVN-LPGEHGQRLPISRNTFAEVTGLSPGVTYYFKV 977
             +T+ W  P S    AV GY +++   N +  +   +L I R T  +VT +S G+ Y F+V
Sbjct: 26686 ITVGWHEPVSNGGSAVVGYHLEMKDRNSILWQKANKLVI-RTTHFKVTTISAGLIYEFRV 26744

Query: 978   FAVSHGRESKPL-TAQQTTKLDA---PTNLQFVNETDSTVLVRWTPPR----AQITGYRL 1029
             +A +     KP   ++    +DA   P N++  + + ++V + W  P     ++ITGY  
Sbjct: 26745 YAENAAGVGKPSHPSEPVLAIDACEPPRNVRITDISKNSVSLSWQQPAFDGGSKITGYI- 26803

Query: 1030  TVGLTRRGQP-----RQYNVGPSVSKYPLRNLQPASEYTVSLVA--IKGNQESP-KATGV 1081
                + RR  P     +      + +++ +  L   S+Y   + A    G+  +P +  G 
Sbjct: 26804 ---VERRDLPDGRWTKASFTNVTETQFIISGLTQNSQYEFRVFARNAVGSISNPSEVVGP 26860

Query: 1082  FTTLQ----PGSSIPPYNTEVTE----TTIV----ITWTPAPRI-GFKLGVRPSQGGEAP 1128
              T +     P   +P   TEV +    T++     I+  PAP I  +K            
Sbjct: 26861 ITCIDSYGGPVIDLPLEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVC 26920

Query: 1129  REVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDT 1188
              E T+D  SI++          Y +++        A I  +++    PP           
Sbjct: 26921 VENTTDLASILIKDADRLNSGCYELKLRNAMGSASATIRVQILDKPGPPGGPIEFKTVTA 26980

Query: 1189  GVLTVSWERSTTPD----ITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYN 1244
               +T+ W R    D    IT Y +    T+    + + E  H ++   T   +  G EY 
Sbjct: 26981 EKITLLW-RPPADDGGAKITHYIVEKRETSRVVWSMVSE--HLEECIITTTKIIKGNEYI 27037

Query: 1245  VSVYTVKDDKESVPI-SDTII----------PEVPQLTDLSFVDITDSSIGLRWT-PL-- 1290
               V  V       P+ SD+++          P +P++T      IT +S+ + W+ P+  
Sbjct: 27038 FRVRAVNKYGIGEPLESDSVVAKNAFVTPGPPGIPEVT-----KITKNSMTVVWSRPIAD 27092

Query: 1291  NSSTIIGYRITVVAAGEGIPIFEDFVDSSVGYY------------TVTGLEPGIDYDISV 1338
               S I GY              E     S+G++             VTGL    DY   V
Sbjct: 27093 GGSDISGY------------FLEKRDKKSLGWFKVLKETIRDTRQKVTGLTENSDYQYRV 27140

Query: 1339  ITLINGGE---SAPTTLTQQTAVP-----PPTDLRFTNIGPDTMRVTWAPP---PSIDLT 1387
               +   G+   S P+    + A P     PP  +R  +    ++ + W+ P       +T
Sbjct: 27141 CAVNAAGQGPFSEPSEF-YKAADPIDPPGPPAKIRIADSTKSSITLGWSKPVYDGGSAVT 27199

Query: 1388  NFLVRYSPVKNEE-DVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQ- 1445
              ++V     + EE               V++NL PG  Y   VS+V    +  P+   + 
Sbjct: 27200 GYVVEIRQGEEEEWTTVSTKGEVRTTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEP 27259

Query: 1446  ---KTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRN 1502
                K  L++P  ID       S           +  ++ R  P     +  ++    +R 
Sbjct: 27260 VQAKDILEAPE-IDLDVALRTSVIAKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARY 27318

Query: 1503  SI---------TLTNLTPGT--EYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAAT 1551
             SI         T+  +T     +Y+++I    G  +S  +  +        + L+V   +
Sbjct: 27319 SIENTDSSSLLTIPQVTRNDTGKYILTIENGVGEPKSSTVSVKVLDTPAACQKLQVKHVS 27378

Query: 1552  PTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGL-----KPGVDYT 1606
               ++ + WD P +      I Y     ++  + ++V   K ++T   L     K    + 
Sbjct: 27379 RGTVTLLWDPPLIDGGSPIINYVIEKRDATKRTWSVVSHKCSSTSFKLIDLSEKTPFFFR 27438

Query: 1607  ITVYAVTGRGDSPASSKPISINYRTEIDKP-SQMQVTDVQDNSISVKW----LPSSSPVT 1661
             +      G G+   +++P+      E+  P   + + D    S+ + W        S +T
Sbjct: 27439 VLAENEIGIGEPCETTEPVK---AAEVPAPIRDLSMKDSTKTSVILSWTKPDFDGGSVIT 27495

Query: 1662  GYRVTTTPKNGPGPTKTKTAGPDQT-EMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAV 1720
              Y V    + G G      AG  +T E+ +  L+        V+A+N  G S P+    +
Sbjct: 27496 EYVV---ERKGKGEQTWSHAGISKTCEIEVSQLKEQSVLEFRVFAKNEKGLSDPVTIGPI 27552

Query: 1721  TNIDRPKGLAFT-DVDVDSIKIAWESPQ-GQVSRYRVTY-SSPEDGIHEL---FPAPDGE 1774
             T     K L  T +VD+  I  A  + + G      + Y   P+  I  L    P  + E
Sbjct: 27553 T----VKELIITPEVDLSDIPGAQVTVRIGHNVHLELPYKGKPKPSISWLKDGLPLKESE 27608

Query: 1775  -------EDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPT----DLKFTQ 1823
                    E+   L       E+      + D+   +  +      +  P+     ++F +
Sbjct: 27609 FVRFSKTENKITLSIKNAKKEHGGKYTVILDNAVCRIAVPITVITLGPPSKPKGPIRFDE 27668

Query: 1824  VTPTSLSAQWTPP----NVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKY 1879
             +   S+   W  P      ++T Y +      +T   K +  +   ++  V  L+   +Y
Sbjct: 27669 IKADSVILSWDVPEDNGGGEITCYSIEKRETSQTN-WKMVCSSVARTTFKVPNLVKDAEY 27727

Query: 1880  EVSVYALKDTLTSRPAQGVVTTLEN----VSPPRRARVTDATETTITISWRTKT----ET 1931
             +  V A      S+P    +   ++      PP +  + + T   ++++W          
Sbjct: 27728 QFRVRAENRYGVSQPLVSSIIVAKHQFRIPGPPGKPVIYNVTSDGMSLTWDAPVYDGGSE 27787

Query: 1932  ITGFQVDAVPANGQTPIQRTIKP-DVRSYTITGLQPGTDYKIYLYTLNDNARSSP----V 1986
             +TGF V+    N     +    P   R Y  TGL  G DY+  +Y  N    SSP     
Sbjct: 27788 VTGFHVEKKERNSILWQKVNTSPISGREYRATGLVEGLDYQFRVYAENSAGLSSPSDPSK 27847

Query: 1987  VIDASTAIDAPSNLRFLATTPNSLLVSWQPP----RARITGYIIKYEKPGSPPREVVPRP 2042
                A + +D P    ++  T  ++ + W PP     ++I GY I+ ++ G+         
Sbjct: 27848 FTLAVSPVDPPGTPDYIDVTRETITLKWNPPLRDGGSKIVGYSIE-KRQGNERWVRCNFT 27906

Query: 2043  RPGVTEATITGLEPGTEYTIYVIA 2066
                  + T+TGL PG  Y   +IA
Sbjct: 27907 DVSECQYTVTGLSPGDRYEFRIIA 27930



 Score =  109 bits (272), Expect = 4e-23
 Identities = 299/1423 (21%), Positives = 501/1423 (35%), Gaps = 243/1423 (17%)

Query: 728   VTEITASSFVVSW----VSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPG 783
             +++I A +  +SW          ++ + VE      GD    L    T TS  +  L+PG
Sbjct: 19001 ISDIDADACSLSWHIPLEDGGSNITNYIVEKCDVSRGDWVTAL-ASVTKTSCRVGKLIPG 19059

Query: 784   RKYIVNV-----YQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ--- 835
             ++YI  V     + ISE      +++      P  P +  V +V+   I V W RP    
Sbjct: 19060 QEYIFRVRAENRFGISEPLTSPKMVAQFPFGVPSEPKNARVTKVNKDCIFVAWDRPDSDG 19119

Query: 836   -APITGYRIVYSPS-----VEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQES 889
              +PI GY I          V+ + T +   E       + L  G++Y+  IYA+ +   S
Sbjct: 19120 GSPIIGYLIERKERNSLLWVKANDTLVRSTE----YPCAGLVEGLEYSFRIYALNKAGSS 19175

Query: 890   TPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPVN 945
              P    +  T     D    P   + ++VT   V+++W  P+    S + GY V+     
Sbjct: 19176 PPSKPTEYVTARMPVDPPGKP---EVIDVTKSTVSLIWARPKHDGGSKIIGYFVEA--CK 19230

Query: 946   LPGEHGQRLPISRNTFAE----VTGLSPGVTYYFKVF---AVSHGRESKPLTAQQTTKLD 998
             LPG+   R   + +   +     TGL     Y F+     AV+    S+P         +
Sbjct: 19231 LPGDKWVRCNTAPHQIPQEEYTATGLEEKAQYQFRAIARTAVNISPPSEPSDPVTILAEN 19290

Query: 999   APTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQ----------YNVGPSV 1048
              P  +       S + V+         G  + +  T  G+P                  +
Sbjct: 19291 VPPRIDLSVAMKSLLTVK--------AGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGI 19342

Query: 1049  SKYPLRNL----------QPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEV 1098
                  RNL          + + +YT++     G++ +     V    +PG   PP + ++
Sbjct: 19343 KMAMQRNLCTLELFSVNRKDSGDYTITAENSSGSKSATIKLKVLD--KPG---PPASVKI 19397

Query: 1099  TE---TTIVITWTPAPRIG------FKLGVR-PSQGGEAPREVTSDSGSIVVSGLTPGVE 1148
              +      +++W P    G      + +  R  S+   A    T    S  V  L  G E
Sbjct: 19398 NKMYSDRAMLSWEPPLEDGGSEITNYIVDKRETSRPNWAQVSATVPITSCSVEKLIEGHE 19457

Query: 1149  YVYTIQVLRDGQERDAPIVNKVV--TPLSPPTNLH--LEANPDTGVLTVSWERSTT---P 1201
             Y + I         D       +   P  PP      + +N     +TVSW+        
Sbjct: 19458 YQFRICAENKYGVGDPVFTEPAIAKNPYDPPGRCDPPVISNITKDHMTVSWKPPADDGGS 19517

Query: 1202  DITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTV--------KDD 1253
              ITGY +    T       +      ++ +     L  G EY   V  +         D 
Sbjct: 19518 PITGYLLEKRETQAVNWTKVNRKPIIER-TLKATGLQEGTEYEFRVTAINKAGPGKPSDA 19576

Query: 1254  KESVPISDTIIPEVPQLTDLSFVDITDSSIGLRWTPL---NSSTIIGYRITVVAAGEGIP 1310
              ++    D   P  P      + D T SS+ L W        S IIGY + V  A     
Sbjct: 19577 SKAAYARDPQYPPGPPAFPKVY-DTTRSSVSLSWGKPAYDGGSPIIGYLVEVKRADS--- 19632

Query: 1311  IFEDFVDSSVGY------YTVTGLEPGIDYDISVITLINGGESAPTTL-----TQQTAVP 1359
               +++V  ++        + VTGL     Y   V  +   G S P+ +      +   +P
Sbjct: 19633 --DNWVRCNLPQNLQKTRFEVTGLMEDTQYQFRVYAVNKIGYSDPSDVPDKHYPKDILIP 19690

Query: 1360  P----PTDLRFTNI--GPDTMR----VTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISP 1409
             P      DLR T I     TMR    V   PPP I  +       P  N  D   L I  
Sbjct: 19691 PEGELDADLRKTLILRAGVTMRLYVPVKGRPPPKITWS------KPNVNLRDRIGLDIKS 19744

Query: 1410  SDNAVVL----TNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSF 1465
             +D    L     N     +Y++++ +   + E T +     T    P  +   +I+ +S 
Sbjct: 19745 TDFDTFLRCENVNKYDAGKYILTLENSCGKKEYTIVVKVLDTP-GPPVNVTVKEISKDSA 19803

Query: 1466  TVHWIAP----RATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVA 1521
              V W  P     + I  Y ++                 S+ S  + NL  G  Y   + A
Sbjct: 19804 YVTWEPPIIDGGSPIINYVVQKRDAERKSWSTV-TTECSKTSFRVANLEEGKSYFFRVFA 19862

Query: 1522  LNGREESPLLIGQQSTVSDVPR---------DLEVVAATPTSLLISWDAPAVTVRYYRIT 1572
                  E+   IG      D  +         DL+V + + +S  I W  P        I 
Sbjct: 19863 -----ENEYGIGDPGETRDAVKASQTPGPVVDLKVRSVSKSSCSIGWKKPHSDGGSRIIG 19917

Query: 1573  YGETGGNSPVQEFTVPGSKSTATISGLK---------PGVDYTITVYAVTGRGDSPASSK 1623
             Y        V +F    +K    +  L           G +YT  V A    G+   S  
Sbjct: 19918 Y--------VVDFLTEENKWQRVMKSLSLQYSAKDLTEGKEYTFRVSAENENGEGTPSE- 19968

Query: 1624  PISINYRTEIDKPSQMQVTDVQDNSISVKWLPS----SSPVTGYRVTTTPKNGPGPTKTK 1679
              I++  R ++  P            + +K LP     +   + +R+    K  P P+ + 
Sbjct: 19969 -ITVVARDDVVAP-----------DLDLKGLPDLCYLAKENSNFRLKIPIKGKPAPSVSW 20016

Query: 1680  TAGPD----QTEMTIEGLQPTVEYVV-----------SVYAQNPSGESQPLVQTAVTNID 1724
               G D     T +++E        +V           ++  +N +G  +  +   V    
Sbjct: 20017 KKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKEGTISIKVVGKP 20076

Query: 1725  R-PKG-LAFTDVDVDSIKIAWESPQGQVSRYRVTY-SSPEDGIHELFP--APDGEEDTAE 1779
               P G + F +V  +++ + W  P+         Y     D ++  +   A   ++ T  
Sbjct: 20077 GIPTGPIKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDSVNNKWVTCASAVQKTTFR 20136

Query: 1780  LQGLRPGSEYTVSVVA-----LHDDMESQPLIGTQSTAIP-APTDLKFTQVTPTSLSAQW 1833
             +  L  G EYT  V A     + + ++S+P++      +P AP       V   S+S  W
Sbjct: 20137 VTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVPDAPPPPNIVDVRHDSVSLTW 20196

Query: 1834  TPP----NVQLTGYRVRVTPKEKTGPM-KEINLAP-DSSSVVVSGLMVATKYEVSVYAL- 1886
             T P       +TGY +    KE+   + K  N  P       V+GL    +YE  V A+ 
Sbjct: 20197 TDPKKTGGSPITGYHLEF--KERNSLLWKRANKTPIRMRDFKVTGLTEGLEYEFRVMAIN 20254

Query: 1887  -----KDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKT----ETITGFQV 1937
                  K +L S P    V  L+ + PP +  V + T  ++T+ W          +TG+ V
Sbjct: 20255 LAGVGKPSLPSEP----VVALDPIDPPGKPEVINITRNSVTLIWTEPKYDGGHKLTGYIV 20310

Query: 1938  DA--VPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLN 1978
             +   +P+           P+  ++T+T L  G  Y+  +   N
Sbjct: 20311 EKRDLPSKSWMKANHVNVPEC-AFTVTDLVEGGKYEFRIRAKN 20352



 Score =  108 bits (269), Expect = 8e-23
 Identities = 265/1341 (19%), Positives = 468/1341 (34%), Gaps = 163/1341 (12%)

Query: 780   LLPGRKYIVNVYQISEDGE----QSLILSTSQTTAPDAPPD-PTVDQVDDTSIVVRWSRP 834
             L+ G +YI  V  ++  G+    QS  +       P  PP+ P V  V   +  V W RP
Sbjct: 20536 LIQGNEYIFRVSAVNHYGKGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSWKRP 20595

Query: 835   Q----APITGYRIVYSPSVEGSSTE-LNLPETANSVTLSDLQPGVQYNITIYA-----VE 884
                  + ITGY +             +  P +     ++ LQ G  Y   + A     + 
Sbjct: 20596 VDDGGSEITGYHVERREKKSLRWVRAIKTPVSDLRCKVTGLQEGSTYEFRVSAENRAGIG 20655

Query: 885   ENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPES----AVTGYRVD 940
                E++  V+ ++    P   + P   D      T    ++ W  P       +TGY V+
Sbjct: 20656 PPSEASDSVLMKDAAYPPGPPSNPHVTD-----TTKKSASLAWGKPHYDGGLEITGYVVE 20710

Query: 941   VIPVN----LPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQ--QT 994
                V     +    G  L I++     V  L     Y F++ A++     +P      + 
Sbjct: 20711 HQKVGDEAWIKDTTGTALRITQFV---VPDLQTKEKYNFRISAINDAGVGEPAVIPDVEI 20767

Query: 995   TKLDAPTNLQFVNETDSTVLVR-------WTP----PRAQITGYRLTVGLTRRGQPRQYN 1043
              + +   + +   E   T++VR       + P    P  ++T  +  + L  R       
Sbjct: 20768 VEREMAPDFELDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKNRANIENTE 20827

Query: 1044  VGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTI 1103
                ++   P  N     ++ +++    G +       V  T  P  ++ P  T++T+ ++
Sbjct: 20828 -SFTLLIIPECNRYDTGKFVMTIENPAGKKSGFVNVRVLDTPGPVLNLRP--TDITKDSV 20884

Query: 1104  VITWT-PAPRIGFKLGVRPSQGGEAPREVTSDSGS------IVVSGLTPGVEYVYTIQVL 1156
              + W  P    G ++     +  EA R+  S + +        V+GL+ G EY + +   
Sbjct: 20885 TLHWDLPLIDGGSRITNYIVEKREATRKSYSTATTKCHKCTYKVTGLSEGCEYFFRVMAE 20944

Query: 1157  RD---GQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPD---ITGYRITT 1210
              +   G+  +     K     SPP +L++  +     ++++W +        ITGY I  
Sbjct: 20945 NEYGIGEPTETTEPVKASEAPSPPDSLNI-MDITKSTVSLAWPKPKHDGGSKITGYVIEA 21003

Query: 1211  TPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISD--TIIPEVP 1268
                   Q   +  V   +   C   NL+ G EY   V  V     S P      I+ E  
Sbjct: 21004 QRKGSDQWTHITTVKGLE---CVVRNLTEGEEYTFQVMAVNSAGRSAPRESRPVIVKEQT 21060

Query: 1269  QLTDLSFVDITDSSIGLRWTPLNSSTI--IGYRITVVAAGEGIPI--------FEDFVDS 1318
              L +L    I    +  +        I  +G     V   +G  I        FE    S
Sbjct: 21061 MLPELDLRGIYQKLVIAKAGDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATS 21120

Query: 1319  SVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTW 1378
             ++             Y ++   ++       T        PP   ++F  +  D +  +W
Sbjct: 21121 TILNINECVRSDSGPYPLTARNIVGEVGDVITIQVHDIPGPPTGPIKFDEVSSDFVTFSW 21180

Query: 1379  APPPS---IDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSS---- 1431
              PP +   + ++N++V      +   V EL+ +        T L  G EY   V +    
Sbjct: 21181 DPPENDGGVPISNYVVEMRQTDSTTWV-ELATTVIRTTYKATRLTTGLEYQFRVKAQNRY 21239

Query: 1432  -VYEQHESTPLRGRQKTGLDSPTGI-DFSDITANSFTVHWIAP----RATITGYRIRHHP 1485
              V     S  +       +  P G    + +T +S T+ W  P     + I GY +    
Sbjct: 21240 GVGPGITSACIVANYPFKVPGPPGTPQVTAVTKDSMTISWHEPLSDGGSPILGYHVERKE 21299

Query: 1486  EHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN-------GREESPLLIGQQSTV 1538
              +        +     N    + LT G  Y   ++A N        +   P+L       
Sbjct: 21300 RNGILWQTVSKALVPGNIFKSSGLTDGIAYEFRVIAENMAGKSKPSKPSEPMLALDPIDP 21359

Query: 1539  SDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPG----SKSTA 1594
                P  L +   T T   + W  P  T  +   +Y     + P   +         ++  
Sbjct: 21360 PGKPVPLNITRHTVT---LKWAKPEYTGGFKITSYIVEKRDLPNGRWLKANFSNILENEF 21416

Query: 1595  TISGLKPGVDYTITVYAVTGRGD-SPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKW 1653
             T+SGL     Y   V A    G  SP S    +I  R +++ P        +D  I    
Sbjct: 21417 TVSGLTEDAAYEFRVIAKNAAGAISPPSEPSDAITCRDDVEAPKIKVDVKFKDTVI---- 21472

Query: 1654  LPSSSPVTGYRVTTTPKNGPGPTK------TKTAGPDQTEMTIEGLQPTV---------E 1698
                      +R+       P PT        +  G  + E+ I      +          
Sbjct: 21473 ---LKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDS 21529

Query: 1699  YVVSVYAQNPSGESQPLVQTAVTNIDRP----KGLAFTDVDVDSIKIAWESP---QGQVS 1751
                ++ A NP G ++ +    V  +DRP      LA T+V  +   ++W  P    G   
Sbjct: 21530 GAYTLTATNPGGFAKHIFNVKV--LDRPGPPEGPLAVTEVTSEKCVLSWFPPLDDGGAKI 21587

Query: 1752  RYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALH-----DDMESQPLI 1806
              + +        +     A + +    ++  L  G+EY   V+A++     + +ES+P++
Sbjct: 21588 DHYIVQKRETSRLAWTNVASEVQVTKLKVTKLLKGNEYIFRVMAVNKYGVGEPLESEPVL 21647

Query: 1807  GTQSTAIP-APTDLKFTQVTPTSLSAQWTPPN----VQLTGYRVRVTPKEKTGPMKEINL 1861
                    P  P + + T +T  S+   W  P+     ++  Y V    K     +K    
Sbjct: 21648 AVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEIINYIVERRDKAGQRWIKCNKK 21707

Query: 1862  APDSSSVVVSGLMVATKYEVSVYA-----LKDTLTSRPAQGVVTTLENVSPPRRARVTDA 1916
                     VSGL    +YE  + A     +     + P      T+    PP   RV D 
Sbjct: 21708 TLTDLRYKVSGLTEGHEYEFRIMAENAAGISAPSPTSPFYKACDTVFKPGPPGNPRVLDT 21767

Query: 1917  TETTITISWRTKT----ETITGFQVD-AVPANGQTPIQRTIKP----DVRSYTITGLQPG 1967
             + ++I+I+W          ITG+ V+ A+P   +  I   + P       SYTITGL   
Sbjct: 21768 SRSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQI---VTPPAGLKATSYTITGLTEN 21824

Query: 1968  TDYKIYLYTLNDNARSSPVVI 1988
              +YKI +Y +N      P ++
Sbjct: 21825 QEYKIRIYAMNSEGLGEPALV 21845



 Score =  107 bits (268), Expect = 1e-22
 Identities = 324/1575 (20%), Positives = 574/1575 (36%), Gaps = 187/1575 (11%)

Query: 552   RWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCY-----GRGIGEWHCQPLQTYP 606
             RWK    D  +    G  Y++       + G  YQ   Y     G G       P     
Sbjct: 16362 RWKRVNRDPIKAMTLGVSYKVTG----LIEGSDYQFRVYAINAAGVGPASLPSDPATARD 16417

Query: 607   SSSGPVEVFITETPSQPNSHPIQWNAPQP---SHISKYILRWRP--KNSVGRWKEATIPG 661
               + P   F   T    +S  ++W+ P     S ++ YI+ ++   K    + K+  + G
Sbjct: 16418 PIAPPGPPFPKVTDWTKSSADLEWSPPLKDGGSKVTGYIVEYKEEGKEEWEKGKDKEVRG 16477

Query: 662   HLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPL 721
                   + GLK G  Y+ ++ ++   G  E              + S  +  + +    +
Sbjct: 16478 --TKLVVTGLKEGAFYKFRVRAVNIAGIGEPGEVT-DVIEMKDRLVSPDLQLDASVRDRI 16534

Query: 722   VATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTA--TSVNIPD 779
             V  +  V  I      +++VS     +   V + ++E    PQ   + +TA  +S+ I +
Sbjct: 16535 VVHAGGVIRI------IAYVSGKPPPT---VTWNMNER-TLPQEATIETTAISSSMVIKN 16584

Query: 780   LLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTV-DQVDDTSIVVRWSRPQ--- 835
                  + + ++   +E GE+   +       P     P +   + + S  + W  P+   
Sbjct: 16585 CQRSHQGVYSLLAKNEAGERKKTIIVDVLDVPGPVGTPFLAHNLTNESCKLTWFSPEDDG 16644

Query: 836   -APITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVI 894
              +PIT Y I    S   + T +    T  + T+  L  G  Y   I A E +    P V 
Sbjct: 16645 GSPITNYVIEKRESDRRAWTPVTYTVTRQNATVQGLIQGKAYFFRI-AAENSIGMGPFVE 16703

Query: 895   QQETTGTPRSDTVPS-PRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPVNLPGE 949
               E        TVP  P DL+  EVT   VT+ W PP+    S +  Y   V+   L G 
Sbjct: 16704 TSEALVIREPITVPERPEDLEVKEVTKNTVTLTWNPPKYDGGSEIINY---VLESRLIGT 16760

Query: 950   HGQRLPISRNTFAE---VTGLSPGVTYYFKVFAVS---HGRES---KPLT-----AQQTT 995
                    + N  +    V GL  G TY ++V AV+    G+ S   KP+T     A  T 
Sbjct: 16761 EKFHKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGKPSFCTKPITCKDELAPPTL 16820

Query: 996   KLDAPTNLQF-VNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLR 1054
              LD    L   V E  +        P+ +++ ++    +    +        +++   ++
Sbjct: 16821 HLDFRDKLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATLALEKIK 16880

Query: 1055  -NLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYN-TEVTETTIVITWTP--- 1109
                  + +Y V +    G+++      V    +PG  + P +  EVT+  +VI+W P   
Sbjct: 16881 AKRSDSGKYCVVVENSTGSRKGFCQVNVVD--RPGPPVGPVSFDEVTKDYMVISWKPPLD 16938

Query: 1110  --APRIGFKLGVRPSQGGEAPREVTSDSGSIV--VSGLTPGVEYVYTIQV-----LRDGQ 1160
                 +I   +  +   G +    VTS S      VS L  G +Y++ I       + D  
Sbjct: 16939 DGGSKITNYIIEKKEVGKDVWMPVTSASAKTTCKVSKLLEGKDYIFRIHAENLYGISDPL 16998

Query: 1161  ERDA-PIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGN 1219
               D+    ++   P +P   +  E   D+ ++T +        IT Y +    T  ++  
Sbjct: 16999 VSDSMKAKDRFRVPDAPDQPIVTEVTKDSALVTWNKPHDGGKPITNYILEKRETMSKRWA 17058

Query: 1220  SLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKD------DKESVPI--SDTIIPEVPQLT 1271
              + +      +     +L  G +Y   V    +         S P+   D I    P + 
Sbjct: 17059 RVTKDPIHPYTKFRVPDLLEGCQYEFRVSAENEIGIGDPSPPSKPVFAKDPIAKPSPPVN 17118

Query: 1272  DLSFVDITDSSIGLRWTPL---NSSTIIGYRITVVAAGEGIPIFEDFVDSSV--GYYTVT 1326
                 +D T +S+ L W P      S I+GY +     G+      +    S     Y VT
Sbjct: 17119 P-EAIDTTCNSVDLTWQPPRHDGGSKILGYIVEYQKVGDEEWRRANHTPESCPETKYKVT 17177

Query: 1327  GLEPGIDYDISVITLINGGESAPTTLTQQTAV----PPPTDLRFTNIG-------PDTMR 1375
             GL  G  Y   V+ +   GES P  + +   V     PP  +   N+         DT+R
Sbjct: 17178 GLRDGQTYKFRVLAVNAAGESDPAHVPEPVLVKDRLEPPELILDANMAREQHIKVGDTLR 17237

Query: 1376  ----VTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLL--PGTEYVVSV 1429
                 +   P P +       R +P K     A + ++P  + + + N     G  Y ++V
Sbjct: 17238 LSAIIKGVPFPKVTWKK-EDRDAPTK-----ARIDVTPVGSKLEIRNAAHEDGGIYSLTV 17291

Query: 1430  SS-VYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAP----RATITGYRIRHH 1484
              +    +  S  +    K G   P  ++ S+I  +S  + W  P     + IT Y +   
Sbjct: 17292 ENPAGSKTVSVKVLVLDKPG--PPRDLEVSEIRKDSCYLTWKEPLDDGGSVITNYVVERR 17349

Query: 1485  PEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVS----- 1539
              +  S +         + S    +L  G +Y+  + A N     P +   +   +     
Sbjct: 17350 -DVASAQWSPLSATSKKKSHFAKHLNEGNQYLFRVAAENQYGRGPFVETPKPIKALDPLH 17408

Query: 1540  --DVPRDLEVVAATPTSLLISWDAP----AVTVRYYRITYGETGGNSPVQEFTVPGSKST 1593
                 P+DL  V    T + + W+ P       +  Y + Y E G    ++  TV  +   
Sbjct: 17409 PPGPPKDLHHVDVDKTEVSLVWNKPDRDGGSPITGYLVEYQEEGTQDWIKFKTV--TNLE 17466

Query: 1594  ATISGLKPGVDYTITVYA--VTGRGDSPASSKPISINYR-----TEIDKPSQMQVTDVQD 1646
               ++GL+ G  Y   V A  + G G  P ++ PI    +      E+D      +     
Sbjct: 17467 CVVTGLQQGKTYRFRVKAENIVGLG-LPDTTIPIECQEKLVPPSVELDVKLIEGLVVKAG 17525

Query: 1647  NSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTE-----MTIEGL--QPTVEY 1699
              ++    +    PV   + TT         KT      +T+     +TI+    + T EY
Sbjct: 17526 TTVRFPAIIRGVPVPTAKWTTDGSE----IKTDEHYTVETDNFSSVLTIKNCLRRDTGEY 17581

Query: 1700  VVSVYAQNPSGESQPLVQTAVTNIDRPK--GLAFTDVDVDSIKIAWESPQGQVSRYRVTY 1757
              ++V   N +G     V   V ++  P    +   DV  + + I+W+ P+       + Y
Sbjct: 17582 QITV--SNAAGSKTVAVHLTVLDVPGPPTGPINILDVTPEHMTISWQPPKDDGGSPVINY 17639

Query: 1758  -SSPEDGIHELFPAPDGEEDTAELQ--GLRPGSEYTVSV-----VALHDDMESQPLIGTQ 1809
                 +D   + +          +L+   L+ G EY   V     + +   ++S P +   
Sbjct: 17640 IVEKQDTRKDTWGVVSSGSSKTKLKIPHLQKGCEYVFRVRAENKIGVGPPLDSTPTVAKH 17699

Query: 1810  STAIPAPTDLK-FTQVTPTSLSAQWTPPNVQ----LTGYRVRVTPKEKTGPMKEINLAPD 1864
               + P+P      T +T  + +  WT P       +TGY +    +E TG    +N  P 
Sbjct: 17700 KFSPPSPPGKPVVTDITENAATVSWTLPKSDGGSPITGYYME--RREVTGKWVRVNKTPI 17757

Query: 1865  SS-SVVVSGLMVATKYEVSVYALKDTLTSRPAQG-----VVTTLENVSPPRRARVTDATE 1918
             +     V+GL     YE  V+A      S+P+           ++   PP   ++ D + 
Sbjct: 17758 ADLKFRVTGLYEGNTYEFRVFAENLAGLSKPSPSSDPIKACRPIKPPGPPINPKLKDKSR 17817

Query: 1919  TTITISWRTKT-----ETITGFQVDAVPANGQTPIQRTIKPDV---RSYTITGLQPGTDY 1970
              T  + W TK        I G+ V+     G     R  K ++    ++ + GL  G +Y
Sbjct: 17818 ETADLVW-TKPLSDGGSPILGYVVEC-QKPGTAQWNRINKDELIRQCAFRVPGLIEGNEY 17875

Query: 1971  KIYLYTLNDNARSSP 1985
             +  +   N      P
Sbjct: 17876 RFRIKAANIVGEGEP 17890



 Score =  106 bits (265), Expect = 2e-22
 Identities = 320/1538 (20%), Positives = 543/1538 (35%), Gaps = 226/1538 (14%)

Query: 702   TSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSW----VSASDTVSGFRVEYELS 757
             T  P  S  V  +T    P       VT+++     V W         +++G+ +E    
Sbjct: 18378 TGPPTESKPVIAKTKYDKPGRPDPPEVTKVSKEEMTVVWNPPEYDGGKSITGYFLE---K 18434

Query: 758   EEGDEPQYLDLPSTATS---VNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDA- 813
             +E    +++ +  +A     + + +LLP  +Y   V   +E G     L +    A D  
Sbjct: 18435 KEKHSTRWVPVNKSAIPERRMKVQNLLPDHEYQFRVKAENEIGIGEPSLPSRPVVAKDPI 18494

Query: 814   --PPDPTVDQVDDT---SIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANS 864
               P  PT  +V DT   SI + W +P     API GY +   P +  +S +        +
Sbjct: 18495 EPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAPIIGYVVEMRPKIADASPDEGWKRCNAA 18554

Query: 865   VTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGT------------------PRSDT 906
               L      V+   T+ +++ENQE    V  Q   G                   P  D 
Sbjct: 18555 AQL------VRKEFTVTSLDENQEYEFRVCAQNQVGIGRPAELKEAIKPKEILEPPEIDL 18608

Query: 907   VPSPRDLQFVEV-TDVKV-TIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEV 964
               S R L  V     +++  I+   P   VT  +V +  V      GQ   +    F  +
Sbjct: 18609 DASMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVV---RKGQVDLVDTMAFLVI 18665

Query: 965   TGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAP-TNLQFVNETDSTVLVRWTPPR-- 1021
                +   +  + +  V+   E       +      P ++L+  + T ++  V W PP   
Sbjct: 18666 PNSTRDDSGKYSLTLVNPAGEKAVFVNVRVLDTPGPVSDLKVSDVTKTSCHVSWAPPEND 18725

Query: 1022  --AQITGYRLTVGLTRRGQPRQYNVGPSVSK--YPLRNLQPASEYTVSLVAIKGNQESPK 1077
               +Q+T Y   V      +     V P V K  + + NL P +EY   + A+  N+  P 
Sbjct: 18726 GGSQVTHY--IVEKREADRKTWSTVTPEVKKTSFHVTNLVPGNEYYFRVTAV--NEYGPG 18781

Query: 1078  ATG-----VFTTLQPGSSIPPYNTEVTETT---IVITWTPAPRIG-FKLG--VRPSQGGE 1126
                     V  +       PP   EVTE T     + W P  R G  K+   +   +  E
Sbjct: 18782 VPTDVPKPVLASDPLSEPDPPRKLEVTEMTKNSATLAWLPPLRDGGAKIDGYITSYREEE 18841

Query: 1127  APREVTSDSG-----SIVVSGLTPGVEYVYTI---QVLRDGQERDAPIVNKVVTPLSPPT 1178
              P +  ++       S+VV+GL  G +Y + +     +     R+A  V +    L PP 
Sbjct: 18842 QPADRWTEYSVVKDLSLVVTGLKEGKKYKFRVAARNAVGVSLPREAEGVYEAKEQLLPPK 18901

Query: 1179  NL-----------------HLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSL 1221
              L                 H+   P     T  W++     +T   +     +      +
Sbjct: 18902 ILMPEQITIKAGKKLRIEAHVYGKPHP---TCKWKKGEDEVVTSSHLAVHKADSSSILII 18958

Query: 1222  EEVVHADQS--SCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPEVPQLTDLSFVDIT 1279
             ++V   D    S T +N S               K  V + D   P  P   D+S  DI 
Sbjct: 18959 KDVTRKDSGYYSLTAENSSG----------TDTQKIKVVVMDAPGPPQPPF-DIS--DID 19005

Query: 1280  DSSIGLRW-TPLNS--STIIGYRITV--VAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDY 1334
               +  L W  PL    S I  Y +    V+ G+ +        +S     V  L PG +Y
Sbjct: 19006 ADACSLSWHIPLEDGGSNITNYIVEKCDVSRGDWVTALASVTKTSC---RVGKLIPGQEY 19062

Query: 1335  DISVITLINGGESAPTTLTQQTAVPP------PTDLRFTNIGPDTMRVTWAPPPSIDLTN 1388
                V      G S P T  +  A  P      P + R T +  D + V W  P S D  +
Sbjct: 19063 IFRVRAENRFGISEPLTSPKMVAQFPFGVPSEPKNARVTKVNKDCIFVAWDRPDS-DGGS 19121

Query: 1389  FLVRYSPVKNEEDVAELSISPSDNAVVLTN-----LLPGTEYVVSVSSVYEQHESTPLRG 1443
              ++ Y  ++ +E  + L +  +D  V  T      L+ G EY   + ++ +   S P + 
Sbjct: 19122 PIIGYL-IERKERNSLLWVKANDTLVRSTEYPCAGLVEGLEYSFRIYALNKAGSSPPSKP 19180

Query: 1444  RQ----KTGLDSPTGIDFSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPRED 1495
              +    +  +D P   +  D+T ++ ++ W  P+    + I GY +           R +
Sbjct: 19181 TEYVTARMPVDPPGKPEVIDVTKSTVSLIWARPKHDGGSKIIGYFVEACKLPGDKWVRCN 19240

Query: 1496  RVPHS--RNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTV---SDVPRDLEVVAA 1550
               PH   +   T T L    +Y    +A      SP             +VP  +++  A
Sbjct: 19241 TAPHQIPQEEYTATGLEEKAQYQFRAIARTAVNISPPSEPSDPVTILAENVPPRIDLSVA 19300

Query: 1551  TPTSLLIS------WDAPAVTVRYYRITYGETGGN-SPVQEFTVPGSKSTATIS----GL 1599
               + L +        DA         +++ + G    P +   +   ++  T+       
Sbjct: 19301 MKSLLTVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNR 19360

Query: 1600  KPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLP---- 1655
             K   DYTIT         S + S  I +    +   P+ +++  +  +   + W P    
Sbjct: 19361 KDSGDYTITA-----ENSSGSKSATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLED 19415

Query: 1656  SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPL 1715
               S +T Y V     + P   +     P  T  ++E L    EY   + A+N  G   P+
Sbjct: 19416 GGSEITNYIVDKRETSRPNWAQVSATVPI-TSCSVEKLIEGHEYQFRICAENKYGVGDPV 19474

Query: 1716  -VQTAVT-NIDRPKGLA----FTDVDVDSIKIAWESPQGQ----VSRYRVTYSSPEDGIH 1765
               + A+  N   P G       +++  D + ++W+ P       ++ Y +     +    
Sbjct: 19475 FTEPAIAKNPYDPPGRCDPPVISNITKDHMTVSWKPPADDGGSPITGYLLEKRETQAVNW 19534

Query: 1766  ELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAI------PAPTDL 1819
                      E T +  GL+ G+EY   V A++     +P   +++         P P   
Sbjct: 19535 TKVNRKPIIERTLKATGLQEGTEYEFRVTAINKAGPGKPSDASKAAYARDPQYPPGPPAF 19594

Query: 1820  -KFTQVTPTSLSAQWTPPNVQ----LTGYRVRVTPKEKTGPMKEINLAPD--SSSVVVSG 1872
              K    T +S+S  W  P       + GY V V   +    ++  NL  +   +   V+G
Sbjct: 19595 PKVYDTTRSSVSLSWGKPAYDGGSPIIGYLVEVKRADSDNWVR-CNLPQNLQKTRFEVTG 19653

Query: 1873  LMVATKYEVSVYALKDTLTSRPAQ--GVVTTLENVSPPRRARVTDATETTITISWRTKTE 1930
             LM  T+Y+  VYA+     S P+         + + PP      D  +T I  +  T   
Sbjct: 19654 LMEDTQYQFRVYAVNKIGYSDPSDVPDKHYPKDILIPPEGELDADLRKTLILRAGVTMRL 19713

Query: 1931  TITGFQVDAVPANGQTPIQRT-IKPDVRSYTITGLQ-PGTDYKIYLYTLNDN-------- 1980
                      VP  G+ P + T  KP+V      GL    TD+  +L   N N        
Sbjct: 19714 --------YVPVKGRPPPKITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKYI 19765

Query: 1981  --------ARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPP----RARITGYIIKY 2028
                      +   +V+        P N+     + +S  V+W+PP     + I  Y+++ 
Sbjct: 19766 LTLENSCGKKEYTIVVKVLDTPGPPVNVTVKEISKDSAYVTWEPPIIDGGSPIINYVVQK 19825

Query: 2029  EKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIA 2066
                       V       T   +  LE G  Y   V A
Sbjct: 19826 RDAERKSWSTV-TTECSKTSFRVANLEEGKSYFFRVFA 19862



 Score =  102 bits (255), Expect = 3e-21
 Identities = 297/1362 (21%), Positives = 483/1362 (35%), Gaps = 240/1362 (17%)

Query: 908   PSP-RDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTG 966
             P P R+L+ V+V+  + T+ W PPE    G  +     N   E  +   +  +T++  T 
Sbjct: 18297 PGPVRNLKIVDVSSDRCTVCWDPPEDD-GGCEIQ----NYILEKCETKRMVWSTYS-ATV 18350

Query: 967   LSPGVT---------YYFKVFAVSH-----GRESKPLTAQQTTKLDAP-----TNLQFVN 1007
             L+PG T         Y F+V A +        ESKP+ A+  TK D P       +  V+
Sbjct: 18351 LTPGTTVTRLIEGNEYIFRVRAENKIGTGPPTESKPVIAK--TKYDKPGRPDPPEVTKVS 18408

Query: 1008  ETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSV---SKYPLRNLQPAS 1060
             + + TV+  W PP       ITGY L      +   R   V  S     +  ++NL P  
Sbjct: 18409 KEEMTVV--WNPPEYDGGKSITGYFLEK--KEKHSTRWVPVNKSAIPERRMKVQNLLPDH 18464

Query: 1061  EYTVSLVAIK----GNQESPKATGVFTT-LQPGSSIPPYNTEVTETT---IVITWTP--- 1109
             EY   + A      G    P    V    ++P    PP N  V +TT   I + W     
Sbjct: 18465 EYQFRVKAENEIGIGEPSLPSRPVVAKDPIEPPG--PPTNFRVVDTTKHSITLGWGKPVY 18522

Query: 1110  ---APRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPI 1166
                AP IG+ + +RP     +P     D G    +     V   +T+  L + QE +  +
Sbjct: 18523 DGGAPIIGYVVEMRPKIADASP-----DEGWKRCNAAAQLVRKEFTVTSLDENQEYEFRV 18577

Query: 1167  VNKVVTPLSPPTNLHLEANP-----------DTGVLTVSWERSTTPD--ITGYRITTTPT 1213
               +    +  P  L     P           D  +  +   R+  P       R    P 
Sbjct: 18578 CAQNQVGIGRPAELKEAIKPKEILEPPEIDLDASMRKLVIVRAGCPIRLFAIVRGRPAPK 18637

Query: 1214  NGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDD-------------KESVPIS 1260
                +   ++ VV   Q      +L   + + V   + +DD             +++V ++
Sbjct: 18638 VTWRKVGIDNVVRKGQV-----DLVDTMAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFVN 18692

Query: 1261  DTIIPEVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGYRIT--VVAAGEGIPIFEDFVDS 1318
               ++     ++DL   D+T +S  + W P  +    G ++T  +V   E        V  
Sbjct: 18693 VRVLDTPGPVSDLKVSDVTKTSCHVSWAPPENDG--GSQVTHYIVEKREADRKTWSTVTP 18750

Query: 1319  SVGY--YTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAVP-------PPTDLRFTNI 1369
              V    + VT L PG +Y   V  +   G   PT + +            PP  L  T +
Sbjct: 18751 EVKKTSFHVTNLVPGNEYYFRVTAVNEYGPGVPTDVPKPVLASDPLSEPDPPRKLEVTEM 18810

Query: 1370  GPDTMRVTWAPP---PSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYV 1426
               ++  + W PP       +  ++  Y   +   D         D ++V+T L  G +Y 
Sbjct: 18811 TKNSATLAWLPPLRDGGAKIDGYITSYREEEQPADRWTEYSVVKDLSLVVTGLKEGKKYK 18870

Query: 1427  VSVSSVYEQHESTPLRGR----QKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIR 1482
               V++      S P         K  L  P  +    IT  +             G ++R
Sbjct: 18871 FRVAARNAVGVSLPREAEGVYEAKEQLLPPKILMPEQITIKA-------------GKKLR 18917

Query: 1483  HHPEHFSGRPR--------EDRV----------PHSRNSITLTNLTPGTEYVVSIVALNG 1524
                 H  G+P         ED V            S + + + ++T       S+ A N 
Sbjct: 18918 IEA-HVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGYYSLTAENS 18976

Query: 1525  R----EESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAP----AVTVRYYRITYGET 1576
                  ++  +++         P D+  + A   SL  SW  P       +  Y +   + 
Sbjct: 18977 SGTDTQKIKVVVMDAPGPPQPPFDISDIDADACSL--SWHIPLEDGGSNITNYIVEKCDV 19034

Query: 1577  GGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDS-PASSKPISINYRTEI-D 1634
                  V       +K++  +  L PG +Y   V A    G S P +S  +   +   +  
Sbjct: 19035 SRGDWVTALASV-TKTSCRVGKLIPGQEYIFRVRAENRFGISEPLTSPKMVAQFPFGVPS 19093

Query: 1635  KPSQMQVTDVQDNSISVKW-LPSS---SPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTI 1690
             +P   +VT V  + I V W  P S   SP+ GY +    +N     K        TE   
Sbjct: 19094 EPKNARVTKVNKDCIFVAWDRPDSDGGSPIIGYLIERKERNSLLWVKANDTLVRSTEYPC 19153

Query: 1691  EGLQPTVEYVVSVYAQNPSGESQPLVQTAVTN----IDRPKGLAFTDVDVDSIKIAWESP 1746
              GL   +EY   +YA N +G S P   T        +D P      DV   ++ + W  P
Sbjct: 19154 AGLVEGLEYSFRIYALNKAGSSPPSKPTEYVTARMPVDPPGKPEVIDVTKSTVSLIWARP 19213

Query: 1747  QGQVSRYRVTY-----SSPEDGIHELFPAPDG---EEDTAELQGLRPGSEYTVSVVALHD 1798
             +       + Y       P D       AP     EE TA   GL   ++Y    +A   
Sbjct: 19214 KHDGGSKIIGYFVEACKLPGDKWVRCNTAPHQIPQEEYTAT--GLEEKAQYQFRAIARTA 19271

Query: 1799  DMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLT-GYRVRVTPKEKTG--- 1854
                S P           P+D       P ++ A+  PP + L+   +  +T K  T    
Sbjct: 19272 VNISPP---------SEPSD-------PVTILAENVPPRIDLSVAMKSLLTVKAGTNVCL 19315

Query: 1855  -------PMKEINLAPDSSSVV-VSGLMVATKYEVSVYAL-----KD----TLTSRPAQG 1897
                    PM  ++   D + +    G+ +A +  +    L     KD    T+T+  + G
Sbjct: 19316 DATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTITAENSSG 19375

Query: 1898  V------VTTLENVSPPRRARVTDATETTITISWRTKTET----ITGFQVDAVPANGQTP 1947
                    +  L+   PP   ++         +SW    E     IT + VD    +    
Sbjct: 19376 SKSATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYIVDKRETSRPNW 19435

Query: 1948  IQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTA---IDAPSNLR--- 2001
              Q +    + S ++  L  G +Y+  +   N      PV  + + A    D P       
Sbjct: 19436 AQVSATVPITSCSVEKLIEGHEYQFRICAENKYGVGDPVFTEPAIAKNPYDPPGRCDPPV 19495

Query: 2002  FLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREVVPRPRPGVTEATI--TGLE 2055
                 T + + VSW+PP     + ITGY++  EK  +         R  + E T+  TGL+
Sbjct: 19496 ISNITKDHMTVSWKPPADDGGSPITGYLL--EKRETQAVNWTKVNRKPIIERTLKATGLQ 19553

Query: 2056  PGTEYTIYVIALKNNQKSEPLIGRKKTVQKTPFVTHPGYDTG 2097
              GTEY   V A+    K+ P  G+     K  +   P Y  G
Sbjct: 19554 EGTEYEFRVTAI---NKAGP--GKPSDASKAAYARDPQYPPG 19590



 Score =  102 bits (255), Expect = 3e-21
 Identities = 274/1373 (19%), Positives = 474/1373 (34%), Gaps = 187/1373 (13%)

Query: 766   LDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDT 825
             +DL  T   + IP+         ++  ++  GE+++ ++      P    D  V  V  T
Sbjct: 18654 VDLVDTMAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFVNVRVLDTPGPVSDLKVSDVTKT 18713

Query: 826   SIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETAN-SVTLSDLQPGVQYNITI 880
             S  V W+ P+    + +T Y IV     +  +     PE    S  +++L PG +Y   +
Sbjct: 18714 SCHVSWAPPENDGGSQVTHY-IVEKREADRKTWSTVTPEVKKTSFHVTNLVPGNEYYFRV 18772

Query: 881   YAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTG 936
              AV E     P  + +    +        PR L+  E+T    T+ W PP     + + G
Sbjct: 18773 TAVNEYGPGVPTDVPKPVLASDPLSEPDPPRKLEVTEMTKNSATLAWLPPLRDGGAKIDG 18832

Query: 937   YRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTK 996
             Y         P +      + ++    VTGL  G  Y F+V             A+    
Sbjct: 18833 YITSYREEEQPADRWTEYSVVKDLSLVVTGLKEGKKYKFRV------------AARNAVG 18880

Query: 997   LDAPTNLQFVNETDSTVLVRWTPPR----AQIT---GYRLTVGLTRRGQPR--------- 1040
             +  P   + V E    +L    PP+     QIT   G +L +     G+P          
Sbjct: 18881 VSLPREAEGVYEAKEQLL----PPKILMPEQITIKAGKKLRIEAHVYGKPHPTCKWKKGE 18936

Query: 1041  ---------QYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSI 1091
                        +   S S   ++++        SL A   +    +   V     PG   
Sbjct: 18937 DEVVTSSHLAVHKADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPGPPQ 18996

Query: 1092  PPYN-TEVTETTIVITW-TPAPRIGFKL------GVRPSQGGEAPREVTSDSGSIVVSGL 1143
             PP++ +++      ++W  P    G  +          S+G       +    S  V  L
Sbjct: 18997 PPFDISDIDADACSLSWHIPLEDGGSNITNYIVEKCDVSRGDWVTALASVTKTSCRVGKL 19056

Query: 1144  TPGVEYVYTIQVLRDGQERDAPIVNKVV------TPLSPPTNLHLEANPDTGVLTVSWER 1197
              PG EY++ ++        +     K+V       P  P      + N D   + V+W+R
Sbjct: 19057 IPGQEYIFRVRAENRFGISEPLTSPKMVAQFPFGVPSEPKNARVTKVNKD--CIFVAWDR 19114

Query: 1198  STT---PDITGYRITTTPTNGQQG-NSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDD 1253
               +     I GY I     N      + + +V + +  C    L  GLEY+  +Y +   
Sbjct: 19115 PDSDGGSPIIGYLIERKERNSLLWVKANDTLVRSTEYPCA--GLVEGLEYSFRIYALNKA 19172

Query: 1254  KESVPISDTIIPEVPQLTD----LSFVDITDSSIGLRWTPL---NSSTIIGYRITVV--- 1303
               S P   T         D       +D+T S++ L W        S IIGY +      
Sbjct: 19173 GSSPPSKPTEYVTARMPVDPPGKPEVIDVTKSTVSLIWARPKHDGGSKIIGYFVEACKLP 19232

Query: 1304  --------AAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVI--TLIN----GGESAP 1349
                      A   IP  E         YT TGLE    Y    I  T +N       S P
Sbjct: 19233 GDKWVRCNTAPHQIPQEE---------YTATGLEEKAQYQFRAIARTAVNISPPSEPSDP 19283

Query: 1350  TTLTQQTAVPPPTDLRF-----------TNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKN 1398
              T+  +  VPP  DL             TN+  D   V   P P++          P + 
Sbjct: 19284 VTILAEN-VPPRIDLSVAMKSLLTVKAGTNVCLDA-TVFGKPMPTVSWKKDGTLLKPAEG 19341

Query: 1399  EEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHEST-PLRGRQKTGLDSPTGIDF 1457
              +   + ++   +  +   N     +Y ++  +      +T  L+   K G   P  +  
Sbjct: 19342 IKMAMQRNLCTLE--LFSVNRKDSGDYTITAENSSGSKSATIKLKVLDKPG--PPASVKI 19397

Query: 1458  SDITANSFTVHWIAP----RATITGYRIRHHPEHFSGRPREDRVPHS--RNSITLTNLTP 1511
             + + ++   + W  P     + IT Y +    +  + RP   +V  +    S ++  L  
Sbjct: 19398 NKMYSDRAMLSWEPPLEDGGSEITNYIV---DKRETSRPNWAQVSATVPITSCSVEKLIE 19454

Query: 1512  GTEYVVSIVALNGREESPLLIGQQSTVS---DVPR--DLEVVA-ATPTSLLISWDAPA-- 1563
             G EY   I A N       +  + +      D P   D  V++  T   + +SW  PA  
Sbjct: 19455 GHEYQFRICAENKYGVGDPVFTEPAIAKNPYDPPGRCDPPVISNITKDHMTVSWKPPADD 19514

Query: 1564  --VTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRG---DS 1618
                 +  Y +   ET   +  +    P  + T   +GL+ G +Y   V A+   G    S
Sbjct: 19515 GGSPITGYLLEKRETQAVNWTKVNRKPIIERTLKATGLQEGTEYEFRVTAINKAGPGKPS 19574

Query: 1619  PASSKPISINYRTEIDKPSQMQVTDVQDNSISVKW----LPSSSPVTGYRVTTTPKNGPG 1674
              AS    + + +     P+  +V D   +S+S+ W        SP+ GY V     +   
Sbjct: 19575 DASKAAYARDPQYPPGPPAFPKVYDTTRSSVSLSWGKPAYDGGSPIIGYLVEVKRADSDN 19634

Query: 1675  PTKTK-TAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFT- 1732
               +        +T   + GL    +Y   VYA N  G S P   + V +   PK +    
Sbjct: 19635 WVRCNLPQNLQKTRFEVTGLMEDTQYQFRVYAVNKIGYSDP---SDVPDKHYPKDILIPP 19691

Query: 1733  --DVDVDSIKIAWESPQGQVSRY---------RVTYSSPEDGIHELFPAPDGEED----- 1776
               ++D D  K         +  Y         ++T+S P   + +         D     
Sbjct: 19692 EGELDADLRKTLILRAGVTMRLYVPVKGRPPPKITWSKPNVNLRDRIGLDIKSTDFDTFL 19751

Query: 1777  TAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPP 1836
               E        +Y +++       E   ++    T  P P ++   +++  S    W PP
Sbjct: 19752 RCENVNKYDAGKYILTLENSCGKKEYTIVVKVLDTPGP-PVNVTVKEISKDSAYVTWEPP 19810

Query: 1837  NVQ----LTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTS 1892
              +     +  Y V+    E+      +      +S  V+ L     Y   V+A  +    
Sbjct: 19811 IIDGGSPIINYVVQKRDAERKS-WSTVTTECSKTSFRVANLEEGKSYFFRVFAENEYGIG 19869

Query: 1893  RPAQ--GVVTTLENVSPPRRARVTDATETTITISWRTK----TETITGFQVDAVPANGQT 1946
              P +    V   +   P    +V   ++++ +I W+         I G+ VD +    + 
Sbjct: 19870 DPGETRDAVKASQTPGPVVDLKVRSVSKSSCSIGWKKPHSDGGSRIIGYVVDFLTEENKW 19929

Query: 1947  PIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSP--VVIDASTAIDAP 1997
               QR +K     Y+   L  G +Y   +   N+N   +P  + + A   + AP
Sbjct: 19930 --QRVMKSLSLQYSAKDLTEGKEYTFRVSAENENGEGTPSEITVVARDDVVAP 19980



 Score =  102 bits (255), Expect = 3e-21
 Identities = 328/1625 (20%), Positives = 588/1625 (36%), Gaps = 231/1625 (14%)

Query: 609   SGPVEVFITETPSQ----------PNSHPIQWNAPQ---PSHISKYILRWRPKNSVGRWK 655
             SG V V + +TP             +S  + W+ P     S I+ YI+  R       + 
Sbjct: 20857 SGFVNVRVLDTPGPVLNLRPTDITKDSVTLHWDLPLIDGGSRITNYIVEKREATRKS-YS 20915

Query: 656   EATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGET 715
              AT   H  +Y + GL  G  Y  ++++  +YG  E        T T+ PV ++      
Sbjct: 20916 TATTKCHKCTYKVTGLSEGCEYFFRVMAENEYGIGE-------PTETTEPVKASE----- 20963

Query: 716   TPFSPLVATSESVTEITASSFVVSWVS----ASDTVSGFRVEYELSEEGDEPQYLDLPST 771
                +P    S ++ +IT S+  ++W          ++G+ +E +  +  D+  ++     
Sbjct: 20964 ---APSPPDSLNIMDITKSTVSLAWPKPKHDGGSKITGYVIEAQ-RKGSDQWTHITTVKG 21019

Query: 772   ATSVNIPDLLPGRKYIVNVYQISEDG-----EQSLILSTSQTTAPDAPPDPTVDQV---- 822
                V + +L  G +Y   V  ++  G     E   ++   QT  P+        ++    
Sbjct: 21020 LECV-VRNLTEGEEYTFQVMAVNSAGRSAPRESRPVIVKEQTMLPELDLRGIYQKLVIAK 21078

Query: 823   --DDTSIVVR-WSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNIT 879
               D+  + +    RP+  +T  +      +   +  +N   TA S T+ ++   V+ +  
Sbjct: 21079 AGDNIKVEIPVLGRPKPTVTWKK---GDQILKQTQRVNFETTATS-TILNINECVRSDSG 21134

Query: 880   IYAVEENQESTPV--VIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPES----A 933
              Y +        V  VI  +    P   T P    ++F EV+   VT  W PPE+     
Sbjct: 21135 PYPLTARNIVGEVGDVITIQVHDIPGPPTGP----IKFDEVSSDFVTFSWDPPENDGGVP 21190

Query: 934   VTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKV-----FAVSHGRESKP 988
             ++ Y V++   +          + R T+ + T L+ G+ Y F+V     + V  G  S  
Sbjct: 21191 ISNYVVEMRQTDSTTWVELATTVIRTTY-KATRLTTGLEYQFRVKAQNRYGVGPGITSAC 21249

Query: 989   LTAQQTTKLDAPTNL-QFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPS 1047
             + A    K+  P    Q    T  ++ + W  P +   G    +G     + R   +  +
Sbjct: 21250 IVANYPFKVPGPPGTPQVTAVTKDSMTISWHEPLSD--GGSPILGYHVERKERNGILWQT 21307

Query: 1048  VSK-------YPLRNLQPASEYTVSLVA--IKGNQESPKATGVFTTLQP----GSSIPPY 1094
             VSK       +    L     Y   ++A  + G  +  K +     L P    G  +P  
Sbjct: 21308 VSKALVPGNIFKSSGLTDGIAYEFRVIAENMAGKSKPSKPSEPMLALDPIDPPGKPVP-- 21365

Query: 1095  NTEVTETTIVITWT-PAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTI 1153
                +T  T+ + W  P    GFK+     +  + P      +G  + +  +  +E  +T+
Sbjct: 21366 -LNITRHTVTLKWAKPEYTGGFKITSYIVEKRDLP------NGRWLKANFSNILENEFTV 21418

Query: 1154  QVLRDGQERDAPIVNK----VVTPLSPPTNL-----HLEANP--------DTGVLTVSWE 1196
               L +    +  ++ K     ++P S P++       +EA          DT +L     
Sbjct: 21419 SGLTEDAAYEFRVIAKNAAGAISPPSEPSDAITCRDDVEAPKIKVDVKFKDTVILKAGEA 21478

Query: 1197  RSTTPDITGYRITTTPTNGQQGNSLE-------------------EVVHADQSSCTFDNL 1237
                  D++G R   T    + G  LE                   +    D  + T    
Sbjct: 21479 FRLEADVSG-RPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDSGAYTLTAT 21537

Query: 1238  SPGLEYNVSVYTVKDDKESVPISDTIIPEVPQLTDLSFVDITDSSIGLRWTPL--NSSTI 1295
             +PG  +   ++ VK      P      PE P    L+  ++T     L W P   +    
Sbjct: 21538 NPG-GFAKHIFNVKVLDRPGP------PEGP----LAVTEVTSEKCVLSWFPPLDDGGAK 21586

Query: 1296  IGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGG-----ESAPT 1350
             I + I        +       +  V    VT L  G +Y   V+ +   G     ES P 
Sbjct: 21587 IDHYIVQKRETSRLAWTNVASEVQVTKLKVTKLLKGNEYIFRVMAVNKYGVGEPLESEPV 21646

Query: 1351  TLTQQTAVP-PPTDLRFTNIGPDTMRVTWAPPPS---IDLTNFLVRYSPVKNEEDVAELS 1406
                     P PP +   T I  D+M V W  P S    ++ N++V       +  +    
Sbjct: 21647 LAVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEIINYIVERRDKAGQRWIKCNK 21706

Query: 1407  ISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTP------LRGRQKTGLDSPTGID-FSD 1459
              + +D    ++ L  G EY   + +      S P       +         P G     D
Sbjct: 21707 KTLTDLRYKVSGLTEGHEYEFRIMAENAAGISAPSPTSPFYKACDTVFKPGPPGNPRVLD 21766

Query: 1460  ITANSFTVHWIAP----RATITGYRIRHH-PEHFSGRPREDRVPHSRNSITLTNLTPGTE 1514
              + +S ++ W  P     + ITGY +    PE    +           S T+T LT   E
Sbjct: 21767 TSRSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQIVTPPAGLKATSYTITGLTENQE 21826

Query: 1515  YVVSIVALNG-------------REESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDA 1561
             Y + I A+N              + E  +L  +    +D+ + + + A     L +    
Sbjct: 21827 YKIRIYAMNSEGLGEPALVPGTPKAEDRMLPPEIELDADLRKVVTIRACCTLRLFVPIKG 21886

Query: 1562  -PAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPA 1620
              PA  V++ R  +GE+   + ++      S S+ T+  +     +    Y +T    S +
Sbjct: 21887 RPAPEVKWAR-DHGESLDKASIE------STSSYTLLIVGNVNRFDSGKYILTVENSSGS 21939

Query: 1621  SSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLP----SSSPVTGYRVTTTPKNGPGPT 1676
              S  +++        P  ++V +V   S+++ W P      S +  Y V          +
Sbjct: 21940 KSAFVNVRVLDTPGPPQDLKVKEVTKTSVTLTWDPPLLDGGSKIKNYIVEKRESTRKAYS 21999

Query: 1677  KTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPL-VQTAVTNIDRPKG---LAFT 1732
                T    +T   ++ LQ    Y   V A+N  G   P     +V   +RP     +   
Sbjct: 22000 TVAT-NCHKTSWKVDQLQEGCSYYFRVLAENEYGIGLPAETAESVKASERPLPPGKITLM 22058

Query: 1733  DVDVDSIKIAWESPQGQVSRYRVTY--SSPEDGIHELFPAPDGEEDTAELQGLRPGSEYT 1790
             DV  +S+ ++WE P+       + Y       G  +       +   A + GL  G EY+
Sbjct: 22059 DVTRNSVSLSWEKPEHDGGSRILGYIVEMQTKGSDKWATCATVKVTEATITGLIQGEEYS 22118

Query: 1791  VSVVALHDDMESQPL-----IGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRV 1845
               V A ++   S P      +  +   IP    L F   T T L+ +    +V   G   
Sbjct: 22119 FRVSAQNEKGISDPRQLSVPVIAKDLVIPPAFKLLFN--TFTVLAGEDLKVDVPFIGRPT 22176

Query: 1846  -RVTPKEKTGPMKEINLAPDSSSVVVSGLMV--ATKYEVSVYALKDTLTSRPAQGV---- 1898
               VT  +   P+K+       S+   S L +  A + +V  Y +K  LT+   + +    
Sbjct: 22177 PAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVK--LTNSAGEAIETLN 22234

Query: 1899  VTTLENVSPPR-RARVTDATETTITISWRTKT----ETITGFQVDAVPANGQTPIQRTIK 1953
             V  L+   PP    ++ + T  +IT+SW         +I  + V+    +  T   + + 
Sbjct: 22235 VIVLDKPGPPTGPVKMDEVTADSITLSWGPPKYDGGSSINNYIVE--KRDTSTTTWQIVS 22292

Query: 1954  PDVRSYTITG--LQPGTDYKIYL-----YTLNDNARSSPVVIDASTAIDAPSNLRFLA-T 2005
               V   TI    L+ G +Y+  +     Y  +    S P V      +  P     +  +
Sbjct: 22293 ATVARTTIKACRLKTGCEYQFRIAAENRYGKSTYLNSEPTVAQYPFKVPGPPGTPVVTLS 22352

Query: 2006  TPNSLLVSWQPP----RARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYT 2061
             + +S+ V W  P     +R+ GY ++ ++  S     + +     T+   TGLE G EY 
Sbjct: 22353 SRDSMEVQWNEPISDGGSRVIGYHLERKERNSILWVKLNKTPIPQTKFKTTGLEEGVEYE 22412

Query: 2062  IYVIA 2066
               V A
Sbjct: 22413 FRVSA 22417



 Score =  102 bits (255), Expect = 3e-21
 Identities = 306/1554 (19%), Positives = 528/1554 (33%), Gaps = 201/1554 (12%)

Query: 610   GPVEVFITETPSQPNSHPIQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSY 666
             GP E  +  T        + WN P     ++IS YI+  R  + +  W + +      +Y
Sbjct: 24803 GPPEGPLKVTGVTAEKCYLAWNPPLQDGGANISHYIIEKRETSRLS-WTQVSTEVQALNY 24861

Query: 667   TIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSE 726
              +  L PG  Y  +++++ +YG  E             P+ S  VT       P   ++ 
Sbjct: 24862 KVTKLLPGNEYIFRVMAVNKYGIGE-------------PLESGPVTACNPYKPPGPPSTP 24908

Query: 727   SVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDE-----PQYLDLPSTATSVNIPDLL 781
              V+ IT  S VV+W    D   G  +E  + E+ D+      +      T   + +  L 
Sbjct: 24909 EVSAITKDSMVVTWARPVDD-GGTEIEGYILEKRDKEGVRWTKCNKKTLTDLRLRVTGLT 24967

Query: 782   PGRKY-----IVNVYQISEDGEQSLILSTSQTTAPDAPP-DPTVDQVDDTSIVVRWSRP- 834
              G  Y       N   + E  E S+         P  PP +P V     +S+ + WS+P 
Sbjct: 24968 EGHSYEFRVAAENAAGVGEPSEPSVFYRACDALYPPGPPSNPKVTDTSRSSVSLAWSKPI 25027

Query: 835   ---QAPITGYRIVYSPSVEGSSTELNLPE--TANSVTLSDLQPGVQYNITIYAVEENQES 889
                 AP+ GY +    +     T    P        T++ L+   +YN  I A+      
Sbjct: 25028 YDGGAPVKGYVVEVKEAAADEWTTCTPPTGLQGKQFTVTKLKENTEYNFRICAINSEGVG 25087

Query: 890   TPVVIQQETTGTPRSD--TVPSPRDLQFVEVTDVKVTI-----MWTPPESAVTGYRVDVI 942
              P  +        R +   +    DL+ V V     T+     +   PE  V   + + I
Sbjct: 25088 EPATLPGSVVAQERIEPPEIELDADLRKVVVLRASATLRLFVTIKGRPEPEVKWEKAEGI 25147

Query: 943   PVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTN 1002
               +   +       +      VT    G   Y      + G ++  +  +      AP N
Sbjct: 25148 LTD-RAQIEVTSSFTMLVIDNVTRFDSG--RYNLTLENNSGSKTAFVNVRVLDSPSAPVN 25204

Query: 1003  LQFVNETDSTVLVRWTPP----RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQP 1058
             L        +V + W PP     A+IT Y +    T R          + + + + NLQ 
Sbjct: 25205 LTIREVKKDSVTLSWEPPLIDGGAKITNYIVEKRETTRKAYATITNNCTKTTFRIENLQE 25264

Query: 1059  ASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYN------TEVTETTIVITW-TPAP 1111
                Y   ++A   + E        TT     S PP         +VT  T  I W  P  
Sbjct: 25265 GCSYYFRVLA---SNEYGIGLPAETTEPVKVSEPPLPPGRVTLVDVTRNTATIKWEKPES 25321

Query: 1112  RIGFKLG----VRPSQGGEAPREVTS-DSGSIVVSGLTPGVEYVYTIQVLR-----DGQE 1161
               G K+        ++G E     T   +    +SGLT G EYV+ +  +      D ++
Sbjct: 25322 DGGSKITGYVVEMQTKGSEKWSTCTQVKTLEATISGLTAGEEYVFRVAAVNEKGRSDPRQ 25381

Query: 1162  RDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDIT-GYRITTTPTNGQQGNS 1220
                P++ + +  + P   L            V        D+    R   T    + G +
Sbjct: 25382 LGVPVIARDI-EIKPSVELPFH------TFNVKAREQLKIDVPFKGRPQATVNWRKDGQT 25434

Query: 1221  LEEVVHADQSS---CTFDNLSPGLEYNVSVY--TVKDDKESVPISDTII------PEVPQ 1269
             L+E    + SS    T  ++    + +V  Y   V +   S+ +  TII      P  P 
Sbjct: 25435 LKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSNSAGSITVPITIIVLDRPGPPGPI 25494

Query: 1270  LTDLSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIFEDFVDSSVGYYT--VTG 1327
               D    +++  SI + W P            +V   E        V  +V   +  +  
Sbjct: 25495 RID----EVSCDSITISWNPPEYDGGCQISNYIVEKKETTSTTWHIVSQAVARTSIKIVR 25550

Query: 1328  LEPGIDYDISVITLINGGESAPTTLTQQTA------VPPPTDLRFTNIGPDTMRVTWAPP 1381
             L  G +Y   V      G+S+ +  +   A        PP   +  +    TM VTW  P
Sbjct: 25551 LTTGSEYQFRVCAENRYGKSSYSESSAVVAEYPFSPPGPPGTPKVVHATKSTMLVTWQVP 25610

Query: 1382  PSIDLTNFLVRYSPVKNEEDV---AELSISPSDNAVVLTNLLPGTEY--------VVSVS 1430
              +   +  +  +   K    +       I  +D  + ++ L  G  Y        +  + 
Sbjct: 25611 VNDGGSRVIGYHLEYKERSSILWSKANKILIADTQMKVSGLDEGLMYEYRVYAENIAGIG 25670

Query: 1431  SVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPR----ATITGYRIRHHPE 1486
                +  E  P R       D P   + ++IT  S ++ W  P     A ITGY +    E
Sbjct: 25671 KCSKSCEPVPAR----DPCDPPGQPEVTNITRKSVSLKWSKPHYDGGAKITGYIVERR-E 25725

Query: 1487  HFSGRPREDRVPHSRNS-ITLTNLTPGTEYVVSIVALNGREE--------SPLLIGQQST 1537
                GR  +    + + +   +T LT    Y   + A N  +          P+++     
Sbjct: 25726 LPDGRWLKCNYTNIQETYFEVTELTEDQRYEFRVFARNAADSVSEPSESTGPIIVKDDVE 25785

Query: 1538  VSDVPRDLE----VVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKST 1593
                V  D++    +V      L I+ D     +    I++ + G     +  T   S   
Sbjct: 25786 PPRVMMDVKFRDVIVVKAGEVLKINADIAGRPLPV--ISWAKDGIEIEERARTEIISTDN 25843

Query: 1594  ATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKP----SQMQVTDVQDNSI 1649
              T+  +K  +      Y +T +  + A ++ +++N +  +DKP      +++  +     
Sbjct: 25844 HTLLTVKDCIRRDTGQYVLTLK--NVAGTRSVAVNCKV-LDKPGPPAGPLEINGLTAEKC 25900

Query: 1650  SVKW---LPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQ 1706
             S+ W            Y +    +               T   +  L    EY+  V   
Sbjct: 25901 SLSWGRPQEDGGADIDYYIVEKRETSHLAWTICEGELQMTSCKVTKLLKGNEYIFRVTGV 25960

Query: 1707  NPSGESQPLVQTAVTNID------RPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSP 1760
             N  G  +PL   A+  +D       P  L  T V  +S+ + W  P+         Y   
Sbjct: 25961 NKYGVGEPLESVAIKALDPFTVPSPPTSLEITSVTKESMTLCWSRPESDGGSEISGYIIE 26020

Query: 1761  EDGIHELFPAPDGEEDTAELQ----GLRPGSEYTVSVVA-----LHDDMESQPLIGTQST 1811
                 + L      ++   +L+    GLR G EY   V A     L    E+ PLI  +  
Sbjct: 26021 RREKNSLRWVRVNKKPVYDLRVKSTGLREGCEYEYRVYAENAAGLSLPSETSPLIRAEDP 26080

Query: 1812  A-IPA-PTDLKFTQVTPTSLSAQWTPP----NVQLTGYRVRVTPKEKTGPMKEINLAPDS 1865
               +P+ P+  K      T+++  W  P       +TGY V     + T     I  +   
Sbjct: 26081 VFLPSPPSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEYKKSDDTDWKTSIQ-SLRG 26139

Query: 1866  SSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENV----------SPPRRARVTD 1915
             +   +SGL    +Y   V ++     S P+      +             S  R+  +  
Sbjct: 26140 TEYTISGLTTGAEYVFRVKSVNKVGASDPSDSSDPQIAKEREEEPLFDIDSEMRKTLIVK 26199

Query: 1916  A-TETTITISWRTK-----------TETITGFQVDAVPANGQTPIQRTIKPDVRSYTITG 1963
             A    T+T+ +R +           T+  T   VD   +     I+   + D   YT+T 
Sbjct: 26200 AGASFTMTVPFRGRPVPNVLWSKPDTDLRTRAYVDTTDSRTSLTIENANRNDSGKYTLT- 26258

Query: 1964  LQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPP 2017
             +Q              +A S  +V+        P+N+     T  S ++SW  P
Sbjct: 26259 IQNVL-----------SAASLTLVVKVLDTPGPPTNITVQDVTKESAVLSWDVP 26301



 Score =  100 bits (248), Expect = 2e-20
 Identities = 162/726 (22%), Positives = 275/726 (37%), Gaps = 92/726 (12%)

Query: 1268  PQLTDLSFVDITDSSIGLRWTPLN---SSTIIGYRITVVAAGEG--IPIFEDFVDSSVGY 1322
             P    +   +I  +SI + W P      + + GY +    A     +P+ E    S+   
Sbjct: 29834 PPTGPIKIDEIDATSITISWEPPELDGGAPLSGYVVEQRDAHRPGWLPVSESVTRST--- 29890

Query: 1323  YTVTGLEPGIDYDISVITLINGG-----ESAPTTLTQQTAVP-PPTDLRFTNIGPDTMRV 1376
             +  T L  G +Y   V      G     +S          +P PP  L+  ++  D M +
Sbjct: 29891 FKFTRLTEGNEYVFRVAATNRFGIGSYLQSEVIECRSSIRIPGPPETLQIFDVSRDGMTL 29950

Query: 1377  TWAPPPS---IDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVY 1433
             TW PP       +T ++V    V+ +  V    +  +      T L  G EY   V+++ 
Sbjct: 29951 TWYPPEDDGGSQVTGYIVERKEVRADRWVRVNKVPVTMTRYRSTGLTEGLEYEHRVTAIN 30010

Query: 1434  EQHESTPLR-GRQKTGLD------SPTGIDFSDITANSFTVHWIAPR----ATITGYRIR 1482
              +    P R  +    +D       P     +D T  S ++ W  P     + +TGY I 
Sbjct: 30011 ARGSGKPSRPSKPIVAMDPIAPPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIE 30070

Query: 1483  HHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVP 1542
                       + +  P      TLT+L  G EY   ++A N         G     ++VP
Sbjct: 30071 MQKVDQHEWTKCNTTPTKIREYTLTHLPQGAEYRFRVLACNA--------GGPGEPAEVP 30122

Query: 1543  RDLEVVAAT--PTSLLISWDAPAVTVRY---YRITYGETGGNSPVQEFTVPGSKSTATIS 1597
               ++V      P   L       + VR     R+T    G   P+ ++T  G +  +  +
Sbjct: 30123 GTVKVTEMLEYPDYELDERYQEGIFVRQGGVIRLTIPIKGKPFPICKWTKEG-QDISKRA 30181

Query: 1598  GLKPGVDYTITVYAVTGRGDS---------PASSKPISINYRTEIDKPSQ----MQVTDV 1644
              +     +T  V     RGDS             K + I  R  I  P+     ++  D+
Sbjct: 30182 MIATSETHTELVIKEADRGDSGTYDLVLENKCGKKAVYIKVRV-IGSPNSPEGPLEYDDI 30240

Query: 1645  QDNSISVKWLPSS----SPVTGYRVTT--TPKNGPGPTKTKTAGPDQTEMTIEGLQPTVE 1698
             Q  S+ V W P +    + + GY +     PK       ++  G   T + ++GL+  VE
Sbjct: 30241 QVRSVRVSWRPPADDGGADILGYILERREVPKAAWYTIDSRVRG---TSLVVKGLKENVE 30297

Query: 1699  YVVSVYAQNPSGESQPLVQ----TAVTNIDRPKGLA----FTDVDVDSIKIAWESPQGQ- 1749
             Y   V A+N  G S+PL      T  T ++ P+  +      DV   S+ ++W  P+   
Sbjct: 30298 YHFRVSAENQFGISKPLKSEEPVTPKTPLNPPEPPSNPPEVLDVTKSSVSLSWSRPKDDG 30357

Query: 1750  VSRYRVTYSSPEDGIHELFPAPDGEEDTAEL---QGLRPGSEYTVSVVALHD------DM 1800
              SR    Y   ++   + +   +  + T  +    GL P +EY   ++A +D        
Sbjct: 30358 GSRVTGYYIERKETSTDKWVRHNKTQITTTMYTVTGLVPDAEYQFRIIAQNDVGLSETSP 30417

Query: 1801  ESQPLIGTQSTAIPA-PTDLKFTQVTPTSLSAQWTPPNV----QLTGYRVRVTPKEKTGP 1855
              S+P++       P+ P +L+   ++  S++ QW  P      ++ GY V       +  
Sbjct: 30418 ASEPVVCKDPFDKPSQPGELEILSISKDSVTLQWEKPECDGGKEILGYWVEYRQSGDSAW 30477

Query: 1856  MKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRP---AQGVVTTL-ENVSPPRRA 1911
              K            + GL+ AT+YE  V+A  +T  SRP   A  + T L    +P  R 
Sbjct: 30478 KKSNKERIKDKQFTIGGLLEATEYEFRVFAENETGLSRPRRTAMSIKTKLTSGEAPGIRK 30537

Query: 1912  RVTDAT 1917
              + D T
Sbjct: 30538 EMKDVT 30543



 Score = 99.8 bits (247), Expect = 3e-20
 Identities = 244/1107 (22%), Positives = 422/1107 (38%), Gaps = 171/1107 (15%)

Query: 1092  PPYNTEVTET---TIVITWT-PAPRIGFKLGVRPSQGGEAPREV------TSDSGSIVVS 1141
             P  N EVTET    + + W  P    G K+     +  +  R+        ++S    V+
Sbjct: 13092 PVRNLEVTETFDGEVSLAWEEPLTDGGSKIIGYVVERRDIKRKTWVLATDRAESCEFTVT 13151

Query: 1142  GLTPG-VEYVYTIQVLR-----DGQERDAPIV--NKVVTPLSPPTNLHLEANPDTGVLTV 1193
             GL  G VEY++ +         +  E D P+   +K   P  PP N+ +      GV ++
Sbjct: 13152 GLQKGGVEYLFRVSARNRVGTGEPVETDNPVEARSKYDVP-GPPLNVTITDVNRFGV-SL 13209

Query: 1194  SWERSTTP---DITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYT- 1249
             +WE        +IT Y I        + ++    V A+  S T  ++  G EY+  V   
Sbjct: 13210 TWEPPEYDGGAEITNYVIELRDKTSIRWDTAM-TVRAEDLSATVTDVVEGQEYSFRVRAQ 13268

Query: 1250  --VKDDKES-----VPISDTIIPEVPQLTDLSFVDITDSSIGLRWTPL---NSSTIIGYR 1299
               +   K S     V ++D I    P + +L+  D T SS+ L+W P      S I+GY 
Sbjct: 13269 NRIGVGKPSAATPFVKVADPIERPSPPV-NLTSSDQTQSSVQLKWEPPLKDGGSPILGYI 13327

Query: 1300  ITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLT------ 1353
             I     G+   I  +        Y VTGLE G  Y   V      G S P+ +       
Sbjct: 13328 IERCEEGKDNWIRCNMKLVPELTYKVTGLEKGNKYLYRVSAENKAGVSDPSEILGPLTAD 13387

Query: 1354  ----------------QQTAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVK 1397
                              +  VP P  +   + G      TW     +  T   V+   +K
Sbjct: 13388 DAFVEPTMDLSAFKDGLEVIVPNPITILVPSTGYPRPTATWCFGDKVLETGDRVK---MK 13444

Query: 1398  NEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHE-STPLRGRQKTGLDSPTGID 1456
                  AEL ISPS+ +      L     V ++S   + +  + P          +P  + 
Sbjct: 13445 TLSAYAELVISPSERSDKGIYTLKLENRVKTISGEIDVNVIARP---------SAPKELK 13495

Query: 1457  FSDITANSFTVHWIAP----RATITGYRIRHHPEHFSGRPREDRVPHSRNSI--TLTNLT 1510
             F DIT +S  + W  P     + +TGY +    +    R    +V      +  T+ +L 
Sbjct: 13496 FGDITKDSVHLTWEPPDDDGGSPLTGYVVE---KREVSRKTWTKVMDFVTDLEFTVPDLV 13552

Query: 1511  PGTEYVVSIVALN-------GREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAP- 1562
              G EY+  + A N          + P+ +   +TV D P +++    T  S+ ++WD P 
Sbjct: 13553 QGKEYLFKVCARNKCGPGEPAYVDEPVNMSTPATVPDPPENVKWRDRTANSIFLTWDPPK 13612

Query: 1563  ---AVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSP 1619
                   ++ Y +     G +  V     P +++   ++GL+ G  Y   V A+  +G   
Sbjct: 13613 NDGGSRIKGYIVERCPRGSDKWV-ACGEPVAETKMEVTGLEEGKWYAYRVKALNRQG--- 13668

Query: 1620  ASSKPISINYRTEIDKPS-QMQVTDVQDNS---ISVKWLPSSSPVTGYRV----TTTPKN 1671
              +SKP          +P+ ++Q  D Q+     + VK L   +   G ++    T T K 
Sbjct: 13669 -ASKP---------SRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKP 13718

Query: 1672  GPGPTKTKT--AGPDQTEMTIEGL--QPTVEYVVS---------VYAQNPSGESQPLVQT 1718
              P  T TK          +TIE +  + TV  V S         + A N  G +  +V+ 
Sbjct: 13719 EPKITWTKADMILKQDKRITIENVPKKSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEV 13778

Query: 1719  AVTNIDR---PKGLAFTDVDVDSIKIAWESPQ----GQVSRYRVTYSSPEDGI-HELFPA 1770
              V  +D+   P     TDV  +S  + W  P+     +++ Y V   + +  + H+L  +
Sbjct: 13779 NV--LDKPGPPAAFDITDVTNESCLLTWNPPRDDGGSKITNYVVERRATDSEVWHKL--S 13834

Query: 1771  PDGEEDTAELQGLRPGSEYTVSVVA-----LHDDMESQPLIGTQSTAIPA-PTDLKFTQV 1824
                ++   +   L P  EY   V A     + + +++ P+        P  PT L+ + +
Sbjct: 13835 STVKDTNFKATKLIPNKEYIFRVAAENMYGVGEPVQASPITAKYQFDPPGPPTRLEPSDI 13894

Query: 1825  TPTSLSAQWTPPN----VQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYE 1880
             T  +++  W  P+      +TGY V     +    ++   +    ++  V GL    KY 
Sbjct: 13895 TKDAVTLTWCEPDDDGGSPITGYWVERLDPDTDKWVRCNKMPVKDTTYRVKGLTNKKKYR 13954

Query: 1881  VSVYALKDTLTSRPAQG-----VVTTLENVSPPRRARVTDATETTITISWRTKTE----- 1930
               V A       +P++      +   ++   PP +  V D  +T++ ++W TK E     
Sbjct: 13955 FRVLAENLAGPGKPSKSTEPILIKDPIDPPWPPGKPTVKDVGKTSVRLNW-TKPEHDGGA 14013

Query: 1931  TITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPV---- 1986
              I  + ++ +       ++         + + GL  G +Y   +  +N    S P     
Sbjct: 14014 KIESYVIEMLKTGTDEWVRVAEGVPTTQHLLPGLMEGQEYSFRVRAVNKAGESEPSEPSD 14073

Query: 1987  VIDASTAIDAPSNLRFLAT---TPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREVV 2039
              +     +  PS  R+L     T N+  + W  P     + IT YI++         + V
Sbjct: 14074 PVLCREKLYPPSPPRWLEVINITKNTADLKWTVPEKDGGSPITNYIVEKRDVRRKGWQTV 14133

Query: 2040  PRPRPGVTEATITGLEPGTEYTIYVIA 2066
                    T+ T+T L  G+ Y   V A
Sbjct: 14134 DTTVKD-TKCTVTPLTEGSLYVFRVAA 14159



 Score = 96.3 bits (238), Expect = 3e-19
 Identities = 294/1454 (20%), Positives = 518/1454 (35%), Gaps = 209/1454 (14%)

Query: 684   IQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSA 743
             I+  G Q + +      + S P+T   +     P  PL      VT +TA    ++W   
Sbjct: 24772 IRTDGGQYILKLSNVGGTKSIPITVKVLDRPGPPEGPL-----KVTGVTAEKCYLAWNPP 24826

Query: 744   SDTVSGFRVEYELSEEGDEPQYLDLPSTATSVN-----IPDLLPGRKYI-----VNVYQI 793
                  G  + + + E+  E   L     +T V      +  LLPG +YI     VN Y I
Sbjct: 24827 LQD-GGANISHYIIEKR-ETSRLSWTQVSTEVQALNYKVTKLLPGNEYIFRVMAVNKYGI 24884

Query: 794   SEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRP----QAPITGYRIVYSPSV 849
              E  E   + + +    P  P  P V  +   S+VV W+RP       I GY I+     
Sbjct: 24885 GEPLESGPVTACNPYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGY-ILEKRDK 24943

Query: 850   EGSSTELNLPETANSVTL--SDLQPGVQYNITIYAVEE---NQESTPVVIQQETTGTPRS 904
             EG        +T   + L  + L  G  Y   + A       + S P V  +        
Sbjct: 24944 EGVRWTKCNKKTLTDLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYR------AC 24997

Query: 905   DTVPSPRDLQFVEVTDV---KVTIMWTPP----ESAVTGYRVDV------------IPVN 945
             D +  P      +VTD     V++ W+ P     + V GY V+V             P  
Sbjct: 24998 DALYPPGPPSNPKVTDTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAADEWTTCTPPTG 25057

Query: 946   LPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLT------AQQ-----T 994
             L G+              VT L     Y F++ A++     +P T      AQ+      
Sbjct: 25058 LQGKQ-----------FTVTKLKENTEYNFRICAINSEGVGEPATLPGSVVAQERIEPPE 25106

Query: 995   TKLDAPTNLQFVNETDSTVLVRWT---PPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKY 1051
              +LDA      V    +T+ +  T    P  ++   +    LT R    Q  V  S +  
Sbjct: 25107 IELDADLRKVVVLRASATLRLFVTIKGRPEPEVKWEKAEGILTDRA---QIEVTSSFTML 25163

Query: 1052  PLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAP 1111
              + N+        +L     +        V     P + +     EV + ++ ++W P  
Sbjct: 25164 VIDNVTRFDSGRYNLTLENNSGSKTAFVNVRVLDSPSAPVNLTIREVKKDSVTLSWEPPL 25223

Query: 1112  RIGFKLGVRPSQGGEAPREVTSDSGSIV----------VSGLTPGVEYVYTIQVLRD--- 1158
               G   G + +      RE T  + + +          +  L  G  Y + +    +   
Sbjct: 25224 IDG---GAKITNYIVEKRETTRKAYATITNNCTKTTFRIENLQEGCSYYFRVLASNEYGI 25280

Query: 1159  GQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT---PDITGYRITTTPTNG 1215
             G   +     KV  P  PP  + L  +      T+ WE+  +     ITGY +       
Sbjct: 25281 GLPAETTEPVKVSEPPLPPGRVTL-VDVTRNTATIKWEKPESDGGSKITGYVVEMQTKGS 25339

Query: 1216  QQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPEVPQLTDLSF 1275
             ++ ++  +V   +    T   L+ G EY   V  V +   S P     +P + +  ++  
Sbjct: 25340 EKWSTCTQVKTLE---ATISGLTAGEEYVFRVAAVNEKGRSDP-RQLGVPVIARDIEIK- 25394

Query: 1276  VDITDSSIGLRWTPLNSSTIIGYRITVVAAG----------EGIPIFEDFVDSSVGYYTV 1325
                   S+ L +   N       +I V   G          +G  + E    +     TV
Sbjct: 25395 -----PSVELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTV 25449

Query: 1326  TGL--EPGIDYDISVITLI----NGGESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTWA 1379
             T L  +     D+    L      G  + P T+       PP  +R   +  D++ ++W 
Sbjct: 25450 TSLSIKEASKEDVGTYELCVSNSAGSITVPITIIVLDRPGPPGPIRIDEVSCDSITISWN 25509

Query: 1380  PPP---SIDLTNFLVRYSPVKNEEDVAE---LSISPSDNAVVLTNLLPGTEYVVSVSS-- 1431
             PP       ++N++V     K E        +S + +  ++ +  L  G+EY   V +  
Sbjct: 25510 PPEYDGGCQISNYIVE----KKETTSTTWHIVSQAVARTSIKIVRLTTGSEYQFRVCAEN 25565

Query: 1432  ---VYEQHESTPLRGRQKTGLDSPTGI-DFSDITANSFTVHWIAP----RATITGYRIRH 1483
                     ES+ +          P G       T ++  V W  P     + + GY + +
Sbjct: 25566 RYGKSSYSESSAVVAEYPFSPPGPPGTPKVVHATKSTMLVTWQVPVNDGGSRVIGYHLEY 25625

Query: 1484  HPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN----GREESPLLIGQQSTVS 1539
                      + +++  +   + ++ L  G  Y   + A N    G+              
Sbjct: 25626 KERSSILWSKANKILIADTQMKVSGLDEGLMYEYRVYAENIAGIGKCSKSCEPVPARDPC 25685

Query: 1540  DVPRDLEVVAATPTSLLISWDAP----AVTVRYYRITYGETGGNSPVQEFTVPGSKSTAT 1595
             D P   EV   T  S+ + W  P       +  Y +   E      ++       ++   
Sbjct: 25686 DPPGQPEVTNITRKSVSLKWSKPHYDGGAKITGYIVERRELPDGRWLKCNYTNIQETYFE 25745

Query: 1596  ISGLKPGVDYTITVYAVTGRGD-SPASSKPISINYRTEIDKPSQMQVTDVQDNSI--SVK 1652
             ++ L     Y   V+A       S  S     I  + +++ P  M     +D  +  + +
Sbjct: 25746 VTELTEDQRYEFRVFARNAADSVSEPSESTGPIIVKDDVEPPRVMMDVKFRDVIVVKAGE 25805

Query: 1653  WLPSSSPVTG--YRVTTTPKNG---PGPTKTKTAGPD-QTEMTIEGL--QPTVEYVVSVY 1704
              L  ++ + G    V +  K+G       +T+    D  T +T++    + T +YV+++ 
Sbjct: 25806 VLKINADIAGRPLPVISWAKDGIEIEERARTEIISTDNHTLLTVKDCIRRDTGQYVLTL- 25864

Query: 1705  AQNPSGESQPLVQTAVTNIDRPKG--LAFTDVDVDSIKIAWESPQ----GQVSRYRVTYS 1758
              +N +G     V   V +   P    L    +  +   ++W  PQ      +  Y V   
Sbjct: 25865 -KNVAGTRSVAVNCKVLDKPGPPAGPLEINGLTAEKCSLSWGRPQEDGGADIDYYIV--- 25920

Query: 1759  SPEDGIHELFPAPDGE--EDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPA- 1815
                +  H  +   +GE    + ++  L  G+EY   V  ++     +PL   +S AI A 
Sbjct: 25921 EKRETSHLAWTICEGELQMTSCKVTKLLKGNEYIFRVTGVNKYGVGEPL---ESVAIKAL 25977

Query: 1816  --------PTDLKFTQVTPTSLSAQWTPP----NVQLTGYRVRVTPKEKTGPMKEINLAP 1863
                     PT L+ T VT  S++  W+ P      +++GY +    K     ++      
Sbjct: 25978 DPFTVPSPPTSLEITSVTKESMTLCWSRPESDGGSEISGYIIERREKNSLRWVRVNKKPV 26037

Query: 1864  DSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQ--GVVTTLENV---SPPRRARVTDATE 1918
                 V  +GL    +YE  VYA      S P++   ++   + V   SPP + ++ D+ +
Sbjct: 26038 YDLRVKSTGLREGCEYEYRVYAENAAGLSLPSETSPLIRAEDPVFLPSPPSKPKIVDSGK 26097

Query: 1919  TTITISWRTKT----ETITGFQVD---AVPANGQTPIQRTIKPDVRSYTITGLQPGTDYK 1971
             TTITI+W          ITG+ V+   +   + +T IQ     +   YTI+GL  G +Y 
Sbjct: 26098 TTITIAWVKPLFDGGAPITGYTVEYKKSDDTDWKTSIQSLRGTE---YTISGLTTGAEYV 26154

Query: 1972  IYLYTLNDNARSSP 1985
               + ++N    S P
Sbjct: 26155 FRVKSVNKVGASDP 26168



 Score = 95.5 bits (236), Expect = 6e-19
 Identities = 319/1473 (21%), Positives = 540/1473 (36%), Gaps = 232/1473 (15%)

Query: 777   IPDLLPGRKYIVNVYQISEDG--EQSLILSTSQTTAPDAPPD------PTVDQVDDTSIV 828
             + DL+ G +Y   V  ++  G  + S  +       PD PP         V++  + +IV
Sbjct: 16078 VEDLVEGGEYEFRVKAVNAAGVSKPSATVGPCDCQRPDMPPSIDLKEFMEVEEGTNVNIV 16137

Query: 829   VR----------WSR--PQAPITGYRIVYSPSVE----GSSTELNLPETANSVTLSDLQP 872
              +          W +  P+ P     ++Y   V       +  L +P++  S T      
Sbjct: 16138 AKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDT------ 16191

Query: 873   GVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE- 931
             G+    TI AV  N  +    ++    G P     P    ++F  V+  ++T+ W PP+ 
Sbjct: 16192 GLY---TITAVN-NLGTASKEMRLNVLGRPGPPVGP----IKFESVSADQMTLSWFPPKD 16243

Query: 932   ---SAVTGYRVDVIPVNLPG-EHGQRLPISRNTFAEVTGLSPGVTYYFKVFA-----VSH 982
                S +T Y ++    N     H    P  +     +  L  G  Y F++ A     +  
Sbjct: 16244 DGGSKITNYVIEKREANRKTWVHVSSEP--KECTYTIPKLLEGHEYVFRIMAQNKYGIGE 16301

Query: 983   GRESKPLTAQQTTKLD-APTNLQFVNETDSTVLVRWTPPR----AQITGYRLTVGLTRRG 1037
               +S+P TA+    +  AP      + T +++ V W  P     + +TGY L +  T   
Sbjct: 16302 PLDSEPETARNLFSVPGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPVTGYWLEMKDTTSK 16361

Query: 1038  QPRQYNVGPSVS-----KYPLRNLQPASEYTVSLVAIKGNQESPK------ATGVFTTLQ 1086
             + ++ N  P  +      Y +  L   S+Y   + AI      P       AT       
Sbjct: 16362 RWKRVNRDPIKAMTLGVSYKVTGLIEGSDYQFRVYAINAAGVGPASLPSDPATARDPIAP 16421

Query: 1087  PGSSIPPYNTEVTETTIVITWTPAPRIGFKLG----VRPSQGGEAPREVTSDSG----SI 1138
             PG   P   T+ T+++  + W+P  + G        V   + G+   E   D       +
Sbjct: 16422 PGPPFPKV-TDWTKSSADLEWSPPLKDGGSKVTGYIVEYKEEGKEEWEKGKDKEVRGTKL 16480

Query: 1139  VVSGLTPGVEYVYTIQVLRD---GQERDAPIVNKVVTPLSPPTNLHLEANP-DTGVLTVS 1194
             VV+GL  G  Y + ++ +     G+  +   V ++   L  P +L L+A+  D  V+   
Sbjct: 16481 VVTGLKEGAFYKFRVRAVNIAGIGEPGEVTDVIEMKDRLVSP-DLQLDASVRDRIVVHAG 16539

Query: 1195  WERSTTPDITGYRITTTPTNGQQGNSLEEVV---HADQSSCTFDNLSPGLEYNVSVYTVK 1251
                     ++G    T   N  +    +E      A  SS    N     +    VY++ 
Sbjct: 16540 GVIRIIAYVSGKPPPTVTWNMNERTLPQEATIETTAISSSMVIKNCQRSHQ---GVYSLL 16596

Query: 1252  DDKESVPISDTIIPEV-----PQLTDLSFVDITDSSIGLRW-TPLNS--STIIGYRITVV 1303
                E+     TII +V     P  T     ++T+ S  L W +P +   S I  Y I   
Sbjct: 16597 AKNEAGERKKTIIVDVLDVPGPVGTPFLAHNLTNESCKLTWFSPEDDGGSPITNYVIEKR 16656

Query: 1304  AAGEGI--PIFEDFVDSSVGYYTVTGLEPGIDY--DISVITLINGGESAPTT----LTQQ 1355
              +      P+       +    TV GL  G  Y   I+    I  G    T+    + + 
Sbjct: 16657 ESDRRAWTPVTYTVTRQNA---TVQGLIQGKAYFFRIAAENSIGMGPFVETSEALVIREP 16713

Query: 1356  TAVPP-PTDLRFTNIGPDTMRVTWAPPP---SIDLTNFLVRYSPVKNEEDVAELSISPSD 1411
               VP  P DL    +  +T+ +TW PP      ++ N+++    +  E+     + +   
Sbjct: 16714 ITVPERPEDLEVKEVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEKFHKVTNDNLLS 16773

Query: 1412  NAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQ----KTGLDSPT-GIDFSDITANSFT 1466
                 +  L  G  Y   VS+V    +  P    +    K  L  PT  +DF D      T
Sbjct: 16774 RKYTVKGLKEGDTYEYRVSAVNIVGQGKPSFCTKPITCKDELAPPTLHLDFRD----KLT 16829

Query: 1467  VHWIAPRATITGYRIRHHPEHFSGRPR------EDRVPHSRNSITLTNLTPGTEYVVSIV 1520
             +  +     +TG         +SG+P+      +D      +  T    TP T  +  I 
Sbjct: 16830 IR-VGEAFALTG--------RYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATLALEKIK 16880

Query: 1521  ALNGREESPLLIGQQST--------VSDVPRDLEVVA------ATPTSLLISWDAP---- 1562
             A         ++ + ST        V+ V R    V        T   ++ISW  P    
Sbjct: 16881 AKRSDSGKYCVVVENSTGSRKGFCQVNVVDRPGPPVGPVSFDEVTKDYMVISWKPPLDDG 16940

Query: 1563  AVTVRYYRITYGETGGN--SPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDS-P 1619
                +  Y I   E G +   PV   T   +K+T  +S L  G DY   ++A    G S P
Sbjct: 16941 GSKITNYIIEKKEVGKDVWMPV---TSASAKTTCKVSKLLEGKDYIFRIHAENLYGISDP 16997

Query: 1620  ASSKPISINYRTEI-DKPSQMQVTDVQDNSISVKWLP---SSSPVTGY---RVTTTPKNG 1672
               S  +    R  + D P Q  VT+V  +S  V W        P+T Y   +  T  K  
Sbjct: 16998 LVSDSMKAKDRFRVPDAPDQPIVTEVTKDSALVTWNKPHDGGKPITNYILEKRETMSKRW 17057

Query: 1673  PGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQN------PSGESQPL-VQTAVTNIDR 1725
                TK        T+  +  L    +Y   V A+N      PS  S+P+  +  +     
Sbjct: 17058 ARVTKDPIH--PYTKFRVPDLLEGCQYEFRVSAENEIGIGDPSPPSKPVFAKDPIAKPSP 17115

Query: 1726  PKGLAFTDVDVDSIKIAWESPQ----GQVSRYRVTYSSPEDGI-HELFPAPDGEEDTA-E 1779
             P      D   +S+ + W+ P+     ++  Y V Y    D         P+   +T  +
Sbjct: 17116 PVNPEAIDTTCNSVDLTWQPPRHDGGSKILGYIVEYQKVGDEEWRRANHTPESCPETKYK 17175

Query: 1780  LQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTS-LSAQWTPPNV 1838
             + GLR G  Y   V+A++   ES P        +P P  +K     P   L A       
Sbjct: 17176 VTGLRDGQTYKFRVLAVNAAGESDP------AHVPEPVLVKDRLEPPELILDANMAREQH 17229

Query: 1839  QLTGYRVRVT------PKEKTGPMKEINLAPDSSSVVVSGLMVATKYEV--------SVY 1884
                G  +R++      P  K    KE   AP  + + V+   V +K E+         +Y
Sbjct: 17230 IKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARIDVTP--VGSKLEIRNAAHEDGGIY 17287

Query: 1885  AL--KDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTE----TITGFQVD 1938
             +L  ++   S+     V  L+   PPR   V++  + +  ++W+   +     IT + V+
Sbjct: 17288 SLTVENPAGSKTVSVKVLVLDKPGPPRDLEVSEIRKDSCYLTWKEPLDDGGSVITNYVVE 17347

Query: 1939  A--VPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPV-------VID 1989
                V +   +P+  T K   +S+    L  G  Y   +   N   R   V        +D
Sbjct: 17348 RRDVASAQWSPLSATSKK--KSHFAKHLNEGNQYLFRVAAENQYGRGPFVETPKPIKALD 17405

Query: 1990  ASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREVVPRPRPG 2045
                    P +L  +      + + W  P     + ITGY+++Y++ G+  ++ +      
Sbjct: 17406 PLHPPGPPKDLHHVDVDKTEVSLVWNKPDRDGGSPITGYLVEYQEEGT--QDWIKFKTVT 17463

Query: 2046  VTEATITGLEPGTEYTIYVIALKNNQKSEPLIG 2078
               E  +TGL+ G  Y   V       K+E ++G
Sbjct: 17464 NLECVVTGLQQGKTYRFRV-------KAENIVG 17489



 Score = 95.1 bits (235), Expect = 7e-19
 Identities = 312/1572 (19%), Positives = 569/1572 (36%), Gaps = 228/1572 (14%)

Query: 616   ITETPSQPNSHPIQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLK 672
             +T T     S  + W  P+    S +  Y++  +PK +  +W         N+  + GL 
Sbjct: 24219 VTLTDVSQTSASLMWEKPEHDGGSRVLGYVVEMQPKGTE-KWSIVAESKVCNA-VVTGLS 24276

Query: 673   PGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETT---PFSP--LVATSES 727
              G  Y+ ++ +  + G  +             PV +  +T + +   PF+   + A  + 
Sbjct: 24277 SGQEYQFRVKAYNEKGKSD-------PRVLGVPVIAKDLTIQPSLKLPFNTYSIQAGEDL 24329

Query: 728   VTEITASSFV---VSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGR 784
               EI         +SWV   + +              +   +++  TATS  +  +  G 
Sbjct: 24330 KIEIPVIGRPRPNISWVKDGEPLK-------------QTTRVNVEETATST-VLHIKEGN 24375

Query: 785   KYIVNVYQISED---GEQSLILSTSQTTAPDAPPDPT-VDQVDDTSIVVRWSRPQ----A 836
             K     Y ++     G  +  LS      P  P  P   D+V    +V+ W  P      
Sbjct: 24376 KDDFGKYTVTATNSAGTATENLSVIVLEKPGPPVGPVRFDEVSADFVVISWEPPAYTGGC 24435

Query: 837   PITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQ 896
              I+ Y +    +   +   ++      ++ ++ L+ G +Y   I+A     +S P+  + 
Sbjct: 24436 QISNYIVEKRDTTTTTWHMVSATVARTTIKITKLKTGTEYQFRIFAENRYGKSAPLDSKA 24495

Query: 897   ETTGTPRSDTVPSPRDLQFV-EVTDVKVTIMWTPPES----AVTGYRVDVIPVN-LPGEH 950
                  P  +  P P    FV  ++  ++ + W  P +     + GY ++    N +    
Sbjct: 24496 VIVQYPFKE--PGPPGTPFVTSISKDQMLVQWHEPVNDGGTKIIGYHLEQKEKNSILWVK 24553

Query: 951   GQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQT----TKLDAPTNLQFV 1006
               + PI    F + TGL  G+ Y FKV A +     KP    +        D P   + +
Sbjct: 24554 LNKTPIQDTKF-KTTGLDEGLEYEFKVSAENIVGIGKPSKVSECFVARDPCDPPGRPEAI 24612

Query: 1007  NETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSV-SKYPLRNLQPASE 1061
               T + V ++W  P     ++ITGY +       G+  + +    + +++ +  L     
Sbjct: 24613 VITRNNVTLKWKKPAYDGGSKITGYIVEKKDLPDGRWMKASFTNVLETEFTVSGLVEDQR 24672

Query: 1062  YTVSLVA--IKGNQESPK-ATGVFTTLQ----PGSSIPPYNTEVT-----ETTIV---IT 1106
             Y   ++A    GN   P  ++G  T       P +S+ P   +V      ET ++   I 
Sbjct: 24673 YEFRVIARNAAGNFSEPSDSSGAITARDEIDAPNASLDPKYKDVIVVHAGETFVLEADIR 24732

Query: 1107  WTPAPRIGFKLGVRPSQGGEAPREVTS--DSGSIVVSGL--TPGVEYVYTIQVLRDGQER 1162
               P P + +    +  +   A  E+ S     ++VV     T G +Y+  +++   G  +
Sbjct: 24733 GKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQYI--LKLSNVGGTK 24790

Query: 1163  DAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWE---RSTTPDITGYRITTTPTNGQQGN 1219
               PI  KV+    PP               ++W    +    +I+ Y I    T+     
Sbjct: 24791 SIPITVKVLDRPGPPEGPLKVTGVTAEKCYLAWNPPLQDGGANISHYIIEKRETSRLSWT 24850

Query: 1220  SLEEVVHADQSSCTFDNLSPGLEY-----NVSVYTVKDDKESVPIS---------DTIIP 1265
              +   V A     T   L PG EY      V+ Y + +  ES P++             P
Sbjct: 24851 QVSTEVQALNYKVT--KLLPGNEYIFRVMAVNKYGIGEPLESGPVTACNPYKPPGPPSTP 24908

Query: 1266  EVPQLTDLSFV-----DITDSSI-------------GLRWTPLNSSTIIGYRITVVAAGE 1307
             EV  +T  S V      + D                G+RWT  N  T+   R+ V    E
Sbjct: 24909 EVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDKEGVRWTKCNKKTLTDLRLRVTGLTE 24968

Query: 1308  GIPI-FEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAVPPPTDLRF 1366
             G    F    +++ G    +  EP + Y         G               PP++ + 
Sbjct: 24969 GHSYEFRVAAENAAGVGEPS--EPSVFYRACDALYPPG---------------PPSNPKV 25011

Query: 1367  TNIGPDTMRVTWAPP---PSIDLTNFLVRYSPVKNEE-DVAELSISPSDNAVVLTNLLPG 1422
             T+    ++ + W+ P       +  ++V       +E                +T L   
Sbjct: 25012 TDTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAADEWTTCTPPTGLQGKQFTVTKLKEN 25071

Query: 1423  TEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGY-RI 1481
             TEY   + ++  +    P                  ++ A+   V  +   AT+  +  I
Sbjct: 25072 TEYNFRICAINSEGVGEPATLPGSVVAQERIEPPEIELDADLRKVVVLRASATLRLFVTI 25131

Query: 1482  RHHPEHFSGRPREDRVPHSRNSITLT---------NLTPGTEYVVSIVALNGREESPLLI 1532
             +  PE      + + +   R  I +T         N+T       ++   N        +
Sbjct: 25132 KGRPEPEVKWEKAEGILTDRAQIEVTSSFTMLVIDNVTRFDSGRYNLTLENNSGSKTAFV 25191

Query: 1533  GQQSTVS-DVPRDLEVVAATPTSLLISWDAPAVT----VRYYRITYGETGGNSPVQEFTV 1587
               +   S   P +L +      S+ +SW+ P +     +  Y +   ET   +     T 
Sbjct: 25192 NVRVLDSPSAPVNLTIREVKKDSVTLSWEPPLIDGGAKITNYIVEKRETTRKA-YATITN 25250

Query: 1588  PGSKSTATISGLKPGVDYTITVYAVT--GRGDSPASSKPISINYRTEIDKPSQMQVTDVQ 1645
               +K+T  I  L+ G  Y   V A    G G    +++P+ ++       P ++ + DV 
Sbjct: 25251 NCTKTTFRIENLQEGCSYYFRVLASNEYGIGLPAETTEPVKVSEPPL--PPGRVTLVDVT 25308

Query: 1646  DNSISVKW-LPSS---SPVTGYRVTTTPKNGPGPTKTKTAGPDQT-EMTIEGLQPTVEYV 1700
              N+ ++KW  P S   S +TGY V    K   G  K  T    +T E TI GL    EYV
Sbjct: 25309 RNTATIKWEKPESDGGSKITGYVVEMQTK---GSEKWSTCTQVKTLEATISGLTAGEEYV 25365

Query: 1701  VSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVD-SIKIAWESPQGQVSRYRVTYSS 1759
               V A N  G S P  Q  V  I R       D+++  S+++ + +   + +R ++    
Sbjct: 25366 FRVAAVNEKGRSDPR-QLGVPVIAR-------DIEIKPSVELPFHTFNVK-AREQLKIDV 25416

Query: 1760  PEDGIHELFP--APDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQ-------- 1809
             P  G  +       DG+    E   +   S  TV+ +++ +   S+  +GT         
Sbjct: 25417 PFKGRPQATVNWRKDGQT-LKETTRVNVSSSKTVTSLSIKE--ASKEDVGTYELCVSNSA 25473

Query: 1810  -STAIPA----------PTDLKFTQVTPTSLSAQWTPPNV----QLTGYRVRVTPKEKTG 1854
              S  +P           P  ++  +V+  S++  W PP      Q++ Y V    KE T 
Sbjct: 25474 GSITVPITIIVLDRPGPPGPIRIDEVSCDSITISWNPPEYDGGCQISNYIVE--KKETTS 25531

Query: 1855  PMKEI-NLAPDSSSVVVSGLMVATKYEVSVYAL----KDTLTSRPAQGVVTTLENVSPPR 1909
                 I + A   +S+ +  L   ++Y+  V A     K + +   A           PP 
Sbjct: 25532 TTWHIVSQAVARTSIKIVRLTTGSEYQFRVCAENRYGKSSYSESSAVVAEYPFSPPGPPG 25591

Query: 1910  RARVTDATETTITISWRTKT----ETITGFQVDAVPANG--QTPIQRTIKPDVRSYTITG 1963
               +V  AT++T+ ++W+         + G+ ++    +    +   + +  D +   ++G
Sbjct: 25592 TPKVVHATKSTMLVTWQVPVNDGGSRVIGYHLEYKERSSILWSKANKILIADTQ-MKVSG 25650

Query: 1964  LQPGTDYKIYLYTLN----DNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPR- 2018
             L  G  Y+  +Y  N         S   + A    D P        T  S+ + W  P  
Sbjct: 25651 LDEGLMYEYRVYAENIAGIGKCSKSCEPVPARDPCDPPGQPEVTNITRKSVSLKWSKPHY 25710

Query: 2019  ---ARITGYIIK 2027
                A+ITGYI++
Sbjct: 25711 DGGAKITGYIVE 25722



 Score = 94.7 bits (234), Expect = 1e-18
 Identities = 315/1607 (19%), Positives = 572/1607 (35%), Gaps = 282/1607 (17%)

Query: 628   IQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISI 684
             + W  P+    + I  Y++    K     W           + + GL  G  Y  ++ ++
Sbjct: 14002 LNWTKPEHDGGAKIESYVIEML-KTGTDEWVRVAEGVPTTQHLLPGLMEGQEYSFRVRAV 14060

Query: 685   QQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSAS 744
              + G  E +              S+ V      + P       V  IT ++  + W +  
Sbjct: 14061 NKAGESEPSE------------PSDPVLCREKLYPPSPPRWLEVINITKNTADLKW-TVP 14107

Query: 745   DTVSGFRVEYELSEEGDEP----QYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGE-- 798
             +   G  +   + E+ D      Q +D     T   +  L  G  Y+  V   +  G+  
Sbjct: 14108 EKDGGSPITNYIVEKRDVRRKGWQTVDTTVKDTKCTVTPLTEGSLYVFRVAAENAIGQSD 14167

Query: 799   ----QSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ----APITGYRIVYSPSVE 850
                 +  +L+    T P  P    V  V    + ++W  P+     PI  Y I     + 
Sbjct: 14168 YTEIEDSVLAKDTFTTPGPPYALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKERL- 14226

Query: 851   GSSTELNLPETAN---SVTLSDLQPGVQYNITIYAVEEN-----QESTPVVIQQETTGTP 902
               +  +   +TA    +  ++D+  G +    + A  E       E T ++  ++ T  P
Sbjct: 14227 -GTRWVKAGKTAGPDCNFRVTDVIEGTEVQFQVRAENEAGVGHPSEPTEILSIEDPTSPP 14285

Query: 903   RSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPVNLPGEHGQRL---P 955
                    P DL   +     + I W PPE    S + GY V++ PV    E   R+   P
Sbjct: 14286 SP-----PLDLHVTDAGRKHIAIAWKPPEKNGGSPIIGYHVEMCPVGT--EKWMRVNSRP 14338

Query: 956   ISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLV 1015
             I    F    G+ P   Y  +V AV+    S+P    +      P     ++     ++V
Sbjct: 14339 IKDLKFKVEEGVVPDKEYVLRVRAVNAIGVSEPSEISENVVAKDPDCKPTIDLETHDIIV 14398

Query: 1016  RWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPL-RNLQPASEYTVSLVAIKGNQE 1074
                     I G +L++ +  R  P      P+VS +   + ++ +   T+    I  + E
Sbjct: 14399 --------IEGEKLSIPVPFRAVPV-----PTVSWHKDGKEVKASDRLTMKNDHISAHLE 14445

Query: 1075  SPKAT----GVFT-TLQP--GSSIPPYN---------------TEVTETTIVITWTP--- 1109
              PK+     G++T TL+   GS+    N               +++T+++  +TW P   
Sbjct: 14446 VPKSVRADAGIYTITLENKLGSATASINVKVIGLPGPCKDIKASDITKSSCKLTWEPPEF 14505

Query: 1110  ---APRIGFKLGVRPSQGGEAPREVTSDSGSI--VVSGLTPGVEYVYTIQVLRD-GQERD 1163
                 P + + L  R + G      V S    +   V  L P  EY + ++ +   G    
Sbjct: 14506 DGGTPILHYVLERREA-GRRTYIPVMSGENKLSWTVKDLIPNGEYFFRVKAVNKVGGGEY 14564

Query: 1164  APIVNKVVT-----PLSPPTNLHLEANPDTGVLTVSWERSTTPD---ITGYRITTTPTNG 1215
               + N V+      P  PP ++ +  NP    +T++W+         I GY I       
Sbjct: 14565 IELKNPVIAQDPKQPPDPPVDVEVH-NPTAEAMTITWKPPLYDGGSKIMGYIIEKIAKGE 14623

Query: 1216  QQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYT-----VKDDKESVPISDTIIP-EVPQ 1269
             ++     E +     + T   L  G EY   V       + +   + P +  + P + P+
Sbjct: 14624 ERWKRCNEHL-VPILTYTAKGLEEGKEYQFRVRAENAAGISEPSRATPPTKAVDPIDAPK 14682

Query: 1270  LTDLSFVDIT-------DSSIG------LRWTPLNSSTIIGYRITVVAA-------GEGI 1309
             +   + +++        D+SI       + W   + + I+   I   AA       GE +
Sbjct: 14683 VILRTSLEVKRGDEIALDASISGSPYPTITWIK-DENVIVPEEIKKRAAPLVRRRKGE-V 14740

Query: 1310  PIFEDFVDSSVGYYTVTGLEPGI-----------DYDISVITLIN--GGESAPTTLTQQT 1356
                E FV       ++   + G            D+ + +I + N  G   AP T++   
Sbjct: 14741 QEEEPFVLPLTQRLSIDNSKKGESQLRVRDSLRPDHGLYMIKVENDHGIAKAPCTVSVLD 14800

Query: 1357  AVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVL 1416
                PP +  F +I   ++   W PP   D  + ++ Y+  K ++        P    +V+
Sbjct: 14801 TPGPPINFVFEDIRKTSVLCKWEPPLD-DGGSEIINYTLEKKDK------TKPDSEWIVV 14853

Query: 1417  TNLLPGTEYVVSVSSVYEQHE------------------STPLRGRQKTG-LDSPTGIDF 1457
             T+ L   +Y  SV+ + E  E                  S PL  +   G  D+P     
Sbjct: 14854 TSTLRHCKY--SVTKLIEGKEYLFRVRAENRFGPGPPCVSKPLVAKDPFGPPDAPDKPIV 14911

Query: 1458  SDITANSFTVHWIAPR---ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTE 1514
              D+T+NS  V W  P+   + I GY +     + +   R ++   +     +  L  G  
Sbjct: 14912 EDVTSNSMLVKWNEPKDNGSPILGYWLEKREVNSTHWSRVNKSLLNALKANVDGLLEGLT 14971

Query: 1515  YVVSIVALN----GREESPLLIGQQSTVSD--------VPRDLEVVAATPTSLLISWDAP 1562
             YV  + A N    G+   P       T  D        +PR   V   + T++ + W+ P
Sbjct: 14972 YVFRVCAENAAGPGKFSPP---SDPKTAHDPISPPGPPIPR---VTDTSSTTIELEWEPP 15025

Query: 1563  AVT----VRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDS 1618
             A      +  Y +     G N   +           T+  ++ G DY + V AV   G+ 
Sbjct: 15026 AFNGGGEIVGYFVDKQLVGTNEWSRCTEKMIKVRQYTVKEIREGADYKLRVSAVNAAGEG 15085

Query: 1619  -PASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTK 1677
              P  ++P+++    E  +P  +++       +SVK           R+       P PTK
Sbjct: 15086 PPGETQPVTV---AEPQEPPAVEL------DVSVKGGIQIMAGKTLRIPAVVTGRPVPTK 15136

Query: 1678  --TKTAGP-DQTEMTIEGLQPTVEYVVS-----------VYAQNPSGESQPLVQTAVTNI 1723
               TK  G  D+  + I+ +    E ++            + A N  G      +  V ++
Sbjct: 15137 VWTKEEGELDKDRVVIDNVGTKSELIIKDALRKDHGRYVITATNSCGSKFAAARVEVFDV 15196

Query: 1724  DRP-KGLAFTDVDVDSIKIAWESPQ----GQVSRYRVTYSSPEDGIHELFPAPDGEEDTA 1778
               P   L     +     + W  P+     +++ + +     +  +H      + E    
Sbjct: 15197 PGPVLDLKPVVTNRKMCLLNWSDPEDDGGSEITGFIIERKDAK--MHTWRQPIETERSKC 15254

Query: 1779  ELQGLRPGSEYTVSVVALH-----DDMESQPLIGTQSTAIP-APTDLKFTQVTPTSLSAQ 1832
             ++ GL  G EY   V+A +       +E  P++       P +P  L +T+ T ++++  
Sbjct: 15255 DITGLLEGQEYKFRVIAKNKFGCGPPVEIGPILAVDPLGPPTSPERLTYTERTKSTITLD 15314

Query: 1833  WTPPNVQ----LTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKD 1888
             W  P       + GY +     +K    +       ++S +V  L     YE  V A+ +
Sbjct: 15315 WKEPRSNGGSPIQGYIIEKRRHDKPDFERVNKRLCPTTSFLVENLDEHQMYEFRVKAVNE 15374

Query: 1889  TLTSRPA--QGVVTTLENVSPPRRARVTDATETTIT-------------------ISWRT 1927
                S P+    VV   + V P  + R++   +T                      I W +
Sbjct: 15375 IGESEPSLPLNVVIQDDEVPPTIKLRLSVRGDTIKVKAGEPVHIPADVTGLPMPKIEW-S 15433

Query: 1928  KTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVV 1987
             K ET+     DA+    +   +   K ++          GT      YT+  + R   V 
Sbjct: 15434 KNETVIEKPTDALQITKEEVSRSEAKTELSIPKAVREDKGT------YTVTASNRLGSVF 15487

Query: 1988  IDASTAI-DAPSNLRFLATT---PNSLLVSWQPP----RARITGYII 2026
              +    + D PS  R LA T     S  ++W  P     + IT Y+I
Sbjct: 15488 RNVHVEVYDRPSPPRNLAVTDIKAESCYLTWDAPLDNGGSEITHYVI 15534



 Score = 93.2 bits (230), Expect = 3e-18
 Identities = 379/1860 (20%), Positives = 656/1860 (35%), Gaps = 386/1860 (20%)

Query: 624   NSHPIQWNAPQPSHISKYILRW---RPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQ 680
             N+  I+W  P     SK I  W   + +N++   KE  +P    +Y + GL  G+ Y+ +
Sbjct: 28855 NAMSIRWEEPYHDGGSKIIGYWVEKKERNTILWVKENKVPCLECNYKVTGLVEGLEYQFR 28914

Query: 681   LISIQQYGHQEVTRFDFTTTSTSTPVTS-NTVTGETTPFSPLVATSESVTEITASSFVVS 739
               ++   G  + +         S P+ + N V     P          VT++T S+  + 
Sbjct: 28915 TYALNAAGVSKASE-------ASRPIMAQNPVDAPGRP---------EVTDVTRSTVSLI 28958

Query: 740   WVSAS----DTVSGFRVEYELSEEGDEPQYLDLPSTATSVN---IPDLLPGRKYIVNVYQ 792
             W + +      V G+ +E +   E  + ++L    T  S N   +  L  G  Y   V  
Sbjct: 28959 WSAPAYDGGSKVVGYIIERKPVSEVGDGRWLKCNYTIVSDNFFTVTALSEGDTYEFRVLA 29018

Query: 793   ISEDGEQSLILSTSQTTAPD------APPDPTVD-QVDDTSIVVRWSRPQAPITGYRIVY 845
              +  G   +I   S++T P       APP   +D ++    + +R         G  +V 
Sbjct: 29019 KNAAG---VISKGSESTGPVTCRDEYAPPKAELDARLHGDLVTIR--------AGSDLVL 29067

Query: 846   SPSVEGS----------STELNLPETANS----------VTLSDLQPGVQYNITIYAVEE 885
               +V G             EL+L E  +           +   D     +Y +T+     
Sbjct: 29068 DAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSGKYTLTVKNASG 29127

Query: 886   NQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDV 941
              +  + +V   ++ G     TV          VT  K T+ W+ P+    + +T Y V+ 
Sbjct: 29128 TKAVSVMVKVLDSPGPCGKLTVS--------RVTQEKCTLAWSLPQEDGGAEITHYIVE- 29178

Query: 942   IPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYY-----------FKVFAVS-HGR----E 985
                        R   SR  +  V G  P ++Y            F+V AV+ +G     E
Sbjct: 29179 -----------RRETSRLNWVIVEGECPTLSYVVTRLIKNNEYIFRVRAVNKYGPGVPVE 29227

Query: 986   SKPLTAQQTTKLDAPTNL-QFVNETDSTVLVRWTPPRA----QITGYRLTVGLTRRGQPR 1040
             S+P+ A+ +  + +P  + + V      ++++WT P +    +I+ Y   V    +   R
Sbjct: 29228 SEPIVARNSFTIPSPPGIPEEVGTGKEHIIIQWTKPESDGGNEISNY--LVDKREKKSLR 29285

Query: 1041  QYNVGPSVSKYPLR----NLQPASEYTVSLVAIK--GNQESPKATGVFTTLQPGSSIPPY 1094
                V      Y  R    +L    +Y   + A+   GN E  +A+   +  +P       
Sbjct: 29286 WTRVNKDYVVYDTRLKVTSLMEGCDYQFRVTAVNAAGNSEPSEASNFISCREP------- 29338

Query: 1095  NTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTP----GVEYV 1150
                        ++TP P         PS    APR V +   SI ++   P    G + V
Sbjct: 29339 -----------SYTPGP---------PS----APRVVDTTKHSISLAWTKPMYDGGTDIV 29374

Query: 1151  -YTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRIT 1209
              Y +++    QE+D     +V          H  A       T+     T PD+      
Sbjct: 29375 GYVLEM----QEKDTDQWYRV----------HTNA-------TIRNTEFTVPDLK----- 29408

Query: 1210  TTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPEVPQ 1269
                  GQ+ +     V+    S          EY+ S+  ++      P+    IP++  
Sbjct: 29409 ----MGQKYSFRVAAVNVKGMS----------EYSESIAEIE------PVERIEIPDLEL 29448

Query: 1270  LTDLSFVDITDSSIGLRWTPLNSSTIIGYRITVVA-AGEGIPIFEDFVDSSVGYYTVTGL 1328
               DL       +   LR       ++ G    V+  + +GI +    +  +   Y++  +
Sbjct: 29449 ADDLKKTVTIRAGASLRLMV----SVSGRPPPVITWSKQGIDLASRAIIDTTESYSLLIV 29504

Query: 1329  EPGIDYDISVITLI---NGGESAPTTLTQQTAVPPPT-DLRFTNIGPDTMRVTWAPPPSI 1384
             +    YD    T+      G+ + T L +    P P   ++   +  D++ +TW  P +I
Sbjct: 29505 DKVNRYDAGKYTIEAENQSGKKSATVLVKVYDTPGPCPSVKVKEVSRDSVTITWEIP-TI 29563

Query: 1385  DLTNFLVRYSPVKNEEDVAE---LSISPSDNAVVLTNLLPGTEYVVSV--SSVY---EQH 1436
             D    +  Y   K E  +     ++   S     ++ L+ GT Y   V   ++Y   E  
Sbjct: 29564 DGGAPVNNYIVEKREAAMRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYGIGEPC 29623

Query: 1437  ESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRP 1492
             E++      +  L  P  ++  D+T ++ T+ W  P     + +TGY +       +G  
Sbjct: 29624 ETSDAVLVSEVPL-VPAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACK---AGTE 29679

Query: 1493  REDRVPHSRNSI---TLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVP-RDLEVV 1548
             R  +V   + ++   T+T+L  G +Y+  I A N +  S      + TV+ V  +DL V+
Sbjct: 29680 RWMKVVTLKPTVLEHTVTSLNEGEQYLFRIRAQNEKGVSE----PRETVTAVTVQDLRVL 29735

Query: 1549  AATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKS---------------- 1592
                  S +          R   +     G   P   +   GSK                 
Sbjct: 29736 PTIDLSTMPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAK 29795

Query: 1593  -TATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQ----MQVTDVQDN 1647
              T   + ++   +YT+ +  VTG      +S+ I +     +DKP      +++ ++   
Sbjct: 29796 LTIRETTIRDTGEYTLELKNVTG-----TTSETIKVII---LDKPGPPTGPIKIDEIDAT 29847

Query: 1648  SISVKWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSV 1703
             SI++ W P      +P++GY V     + PG      +    T      L    EYV  V
Sbjct: 29848 SITISWEPPELDGGAPLSGYVVEQRDAHRPGWLPVSESVTRST-FKFTRLTEGNEYVFRV 29906

Query: 1704  YAQNPSGESQPL------VQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQ----GQVSRY 1753
              A N  G    L       ++++     P+ L   DV  D + + W  P+     QV+ Y
Sbjct: 29907 AATNRFGIGSYLQSEVIECRSSIRIPGPPETLQIFDVSRDGMTLTWYPPEDDGGSQVTGY 29966

Query: 1754  RVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALH------DDMESQPLIG 1807
              V                          GL  G EY   V A++          S+P++ 
Sbjct: 29967 IVERKEVRADRWVRVNKVPVTMTRYRSTGLTEGLEYEHRVTAINARGSGKPSRPSKPIVA 30026

Query: 1808  TQSTAIPA-PTDLKFTQVTPTSLSAQWTPPNVQ----LTGYRVRVTPKEKTGPMKEINLA 1862
                 A P  P + + T  T TS+S  W+ P  +    +TGY + +   ++    K     
Sbjct: 30027 MDPIAPPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTKCNTTP 30086

Query: 1863  PDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQ--GVVTTLENVSPP---------RRA 1911
                    ++ L    +Y   V A        PA+  G V   E +  P            
Sbjct: 30087 TKIREYTLTHLPQGAEYRFRVLACNAGGPGEPAEVPGTVKVTEMLEYPDYELDERYQEGI 30146

Query: 1912  RVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGT--D 1969
              V       +TI  + K      F +      GQ   +R +     ++T   ++     D
Sbjct: 30147 FVRQGGVIRLTIPIKGKP-----FPICKWTKEGQDISKRAMIATSETHTELVIKEADRGD 30201

Query: 1970  YKIYLYTLNDNARSSPVVIDASTAIDAPSN----LRFLATTPNSLLVSWQPPR----ARI 2021
                Y   L +      V I     I +P++    L +      S+ VSW+PP     A I
Sbjct: 30202 SGTYDLVLENKCGKKAVYIKVRV-IGSPNSPEGPLEYDDIQVRSVRVSWRPPADDGGADI 30260

Query: 2022  TGYII-KYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRK 2080
              GYI+ + E P +    +  R R   T   + GL+   EY   V A      S+PL   +
Sbjct: 30261 LGYILERREVPKAAWYTIDSRVRG--TSLVVKGLKENVEYHFRVSAENQFGISKPLKSEE 30318

Query: 2081  KTVQKTPFVTHPGYDTGNGIQLPGTSGQQPSVGQQMIFEEHGFRRTTPPTTATPIRHRPR 2140
                 KTP                                        PP         P 
Sbjct: 30319 PVTPKTPL--------------------------------------NPP--------EPP 30332

Query: 2141  PYPPNVGQEALSQTTISWAPFQD-----TSEYIISCHPVGTDEEPLQFRVPGTSTSATLT 2195
               PP V     S  ++SW+  +D      + Y I      TD+     +   T+T  T+T
Sbjct: 30333 SNPPEVLDVTKSSVSLSWSRPKDDGGSRVTGYYIERKETSTDKWVRHNKTQITTTMYTVT 30392

Query: 2196  GLTRGATYNIIVEALKD---QQRHKVREEVVTVGNSVNEGLNQPTDDSCFDPYTVSHYAV 2252
             GL   A Y   + A  D    +     E VV       +  ++P+     +  ++S  +V
Sbjct: 30393 GLVPDAEYQFRIIAQNDVGLSETSPASEPVV-----CKDPFDKPSQPGELEILSISKDSV 30447

Query: 2253  GDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHDNGVNYKIGEKWDRQGENGQMMSCT 2312
               +WE+    G K   + LG+   + +   S W   N    K     D+Q   G ++  T
Sbjct: 30448 TLQWEKPECDGGK---EILGYWVEYRQSGDSAWKKSNKERIK-----DKQFTIGGLLEAT 30499



 Score = 90.5 bits (223), Expect = 2e-17
 Identities = 317/1530 (20%), Positives = 556/1530 (36%), Gaps = 208/1530 (13%)

Query: 728   VTEITASSFVVSW----VSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPG 783
             +T+I+ +S  +SW          ++G+ VE     +G   +      T T   I  L   
Sbjct: 26776 ITDISKNSVSLSWQQPAFDGGSKITGYIVERRDLPDGRWTKASFTNVTETQFIISGLTQN 26835

Query: 784   RKYIVNVYQISEDGEQSLILSTSQTTAP----DAPPDPTVDQVDDTSIVVRWS-----RP 834
              +Y   V+  +  G    I + S+   P    D+   P +D   + + VV++      + 
Sbjct: 26836 SQYEFRVFARNAVGS---ISNPSEVVGPITCIDSYGGPVIDLPLEYTEVVKYRAGTSVKL 26892

Query: 835   QAPITGYRIVYSPSVEGSSTELNLPETA-----NSVTLSDL--QPGVQYNITIYAVEENQ 887
             +A I+G     +P++E    +  L   A     N+  L+ +  +   + N   Y ++   
Sbjct: 26893 RAGISGKP---APTIEWYKDDKELQTNALVCVENTTDLASILIKDADRLNSGCYELKLRN 26949

Query: 888   E--STPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDV 941
                S    I+ +    P     P    ++F  VT  K+T++W PP     + +T Y V+ 
Sbjct: 26950 AMGSASATIRVQILDKPG----PPGGPIEFKTVTAEKITLLWRPPADDGGAKITHYIVEK 27005

Query: 942   -----IPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTK 996
                  +  ++  EH +   I+       T +  G  Y F+V AV+     +PL +     
Sbjct: 27006 RETSRVVWSMVSEHLEECIIT------TTKIIKGNEYIFRVRAVNKYGIGEPLESDSVVA 27059

Query: 997   LDA-----PTNLQFVNE-TDSTVLVRWTPPRAQ----ITGYRLTVGLTRR-GQPRQYNVG 1045
              +A     P  +  V + T +++ V W+ P A     I+GY L     +  G  +     
Sbjct: 27060 KNAFVTPGPPGIPEVTKITKNSMTVVWSRPIADGGSDISGYFLEKRDKKSLGWFKVLKET 27119

Query: 1046  PSVSKYPLRNLQPASEYTVSLVAIKGNQESP--KATGVFTTLQP-GSSIPPYNTEVTETT 1102
                ++  +  L   S+Y   + A+    + P  + +  +    P     PP    + ++T
Sbjct: 27120 IRDTRQKVTGLTENSDYQYRVCAVNAAGQGPFSEPSEFYKAADPIDPPGPPAKIRIADST 27179

Query: 1103  ---IVITWTP------APRIGFKLGVRPSQGGEAPREVTSDSGSI-----VVSGLTPGVE 1148
                I + W+       +   G+ + +R  QG E      S  G +     VVS L PGV 
Sbjct: 27180 KSSITLGWSKPVYDGGSAVTGYVVEIR--QGEEEEWTTVSTKGEVRTTEYVVSNLKPGVN 27237

Query: 1149  YVYTIQVLRDGQERDAPIVNKVVTP---LSPP---------TNLHLEANPDTGVL----- 1191
             Y + +  +    + +   +N+ V     L  P         T++  +A  D  VL     
Sbjct: 27238 YYFRVSAVNCAGQGEPIEMNEPVQAKDILEAPEIDLDVALRTSVIAKAGEDVQVLIPFKG 27297

Query: 1192  ----TVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSV 1247
                 TV+W +      +  R +   T+     ++ +V   D             +Y +++
Sbjct: 27298 RPPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTG-----------KYILTI 27346

Query: 1248  YTVKDDKESVPISDTIIPEVPQLTDLSFVDITDSSIGLRWTPL---NSSTIIGYRITVVA 1304
                  + +S  +S  ++        L    ++  ++ L W P      S II Y I    
Sbjct: 27347 ENGVGEPKSSTVSVKVLDTPAACQKLQVKHVSRGTVTLLWDPPLIDGGSPIINYVIEKRD 27406

Query: 1305  AGEGIPIFEDFVDSSVGYYTVTGLEPG-IDYDISVITLINGGESAPTTLTQQTA-VPPPT 1362
             A +          SS  +  +   E     + +     I  GE   TT   + A VP P 
Sbjct: 27407 ATKRTWSVVSHKCSSTSFKLIDLSEKTPFFFRVLAENEIGIGEPCETTEPVKAAEVPAPI 27466

Query: 1363  -DLRFTNIGPDTMRVTWAPPP---SIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTN 1418
              DL   +    ++ ++W  P       +T ++V     K E+  +   IS +   + ++ 
Sbjct: 27467 RDLSMKDSTKTSVILSWTKPDFDGGSVITEYVVERKG-KGEQTWSHAGISKTCE-IEVSQ 27524

Query: 1419  LLPGTEYVVSVSSVYEQHESTPLRGRQKT--GLDSPTGIDFSDITANSFTVHWIAPRATI 1476
             L   +     V +  E+  S P+     T   L     +D SDI     TV         
Sbjct: 27525 LKEQSVLEFRVFAKNEKGLSDPVTIGPITVKELIITPEVDLSDIPGAQVTVR-------- 27576

Query: 1477  TGYRIRHHPEHFSGRPRED----------------RVPHSRNSITLT----NLTPGTEYV 1516
              G+ + H    + G+P+                  R   + N ITL+        G +Y 
Sbjct: 27577 IGHNV-HLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGGKYT 27635

Query: 1517  VSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVT----VRYYRIT 1572
             V +     R   P+ +      S     +        S+++SWD P       +  Y I 
Sbjct: 27636 VILDNAVCRIAVPITVITLGPPSKPKGPIRFDEIKADSVILSWDVPEDNGGGEITCYSIE 27695

Query: 1573  YGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDS-PASSKPISINYRT 1631
               ET   +  +      +++T  +  L    +Y   V A    G S P  S  I   ++ 
Sbjct: 27696 KRETSQTN-WKMVCSSVARTTFKVPNLVKDAEYQFRVRAENRYGVSQPLVSSIIVAKHQF 27754

Query: 1632  EID-KPSQMQVTDVQDNSISVKW----LPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQT 1686
              I   P +  + +V  + +S+ W        S VTG+ V    +N     K  T+     
Sbjct: 27755 RIPGPPGKPVIYNVTSDGMSLTWDAPVYDGGSEVTGFHVEKKERNSILWQKVNTSPISGR 27814

Query: 1687  EMTIEGLQPTVEYVVSVYAQNPSGESQPLVQT----AVTNIDRPKGLAFTDVDVDSIKIA 1742
             E    GL   ++Y   VYA+N +G S P   +    AV+ +D P    + DV  ++I + 
Sbjct: 27815 EYRATGLVEGLDYQFRVYAENSAGLSSPSDPSKFTLAVSPVDPPGTPDYIDVTRETITLK 27874

Query: 1743  WESPQGQVSRYRVTYSSPEDGIHELFPA---PDGEEDTAELQGLRPGSEYTVSVVALHDD 1799
             W  P        V YS  +   +E +      D  E    + GL PG  Y   ++A +  
Sbjct: 27875 WNPPLRDGGSKIVGYSIEKRQGNERWVRCNFTDVSECQYTVTGLSPGDRYEFRIIARNAV 27934

Query: 1800  MESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEI 1859
                 P   +QS+ I    D     +       ++    +  +G  +R+    +  P+  +
Sbjct: 27935 GTISP--PSQSSGIIMTRDENVPPIV--EFGPEYFDGLIIKSGESLRIKALVQGRPVPRV 27990

Query: 1860  NLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTT-LENVSPPRRARV-TDAT 1917
                 D   +     M  T    S        T R  +GV T   +N S   +A +     
Sbjct: 27991 TWFKDGVEIEKRMNMEITDVLGSTSLFVRDAT-RDHRGVYTVEAKNASGSAKAEIKVKVQ 28049

Query: 1918  ETTITISWRTKTETITGFQV----DAVPANGQTPIQRTI----------------KPDVR 1957
             +T   +    +   ITG ++    DA   +G  PI   I                K + +
Sbjct: 28050 DTPGKVVGPIRFTNITGEKMTLWWDAPLNDGCAPITHYIIEKRETSRLAWALIEDKCEAQ 28109

Query: 1958  SYTITGLQPGTDYKIYLYTLNDNA-----RSSPVVIDAS-TAIDAPSNLRFLATTPNSLL 2011
             SYT   L  G +Y+  +  +N         S PVV     T  DAP        T NS+ 
Sbjct: 28110 SYTAIKLINGNEYQFRVSAVNKFGVGRPLDSDPVVAQIQYTVPDAPGIPEPSNITGNSIT 28169

Query: 2012  VSWQPPRA----RITGYII-KYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIA 2066
             ++W  P +     I  YI+ + EK  +   +V+ +     T   +TGL  G EY  +V+A
Sbjct: 28170 LTWARPESDGGSEIQQYILERREKKSTRWVKVISKRPISETRFKVTGLTEGNEYEFHVMA 28229

Query: 2067  LKNNQKSEPLIGRKKTVQKTPFVTHPGYDT 2096
              +N     P  G  + ++    V  PG  T
Sbjct: 28230 -ENAAGVGPASGISRLIKCREPVNPPGPPT 28258



 Score = 90.1 bits (222), Expect = 2e-17
 Identities = 348/1626 (21%), Positives = 567/1626 (34%), Gaps = 224/1626 (13%)

Query: 624   NSHPIQWNAPQ---PSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKG--LKPGVVYE 678
             +S  + W  P+    S I+ YI+  R   S   W+   +   +   TIK   LK G  Y+
Sbjct: 22256 DSITLSWGPPKYDGGSSINNYIVEKRD-TSTTTWQ--IVSATVARTTIKACRLKTGCEYQ 22312

Query: 679   GQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVV 738
              ++ +  +YG       + T       V          P +P+V  S      +  S  V
Sbjct: 22313 FRIAAENRYGKSTYLNSEPTVAQYPFKVPG-------PPGTPVVTLS------SRDSMEV 22359

Query: 739   SWVSASDTVSGFRVEYELS-EEGDEPQYLDL---PSTATSVNIPDLLPGRKYI--VNVYQ 792
              W           + Y L  +E +   ++ L   P   T      L  G +Y   V+   
Sbjct: 22360 QWNEPISDGGSRVIGYHLERKERNSILWVKLNKTPIPQTKFKTTGLEEGVEYEFRVSAEN 22419

Query: 793   ISEDGEQSLILSTSQTTAPDAPPD-PTVDQVDDTSIVVRWSRPQ----APITGYRIVYSP 847
             I   G+ S +        P  PP  P    V   S+ ++W +P     + ITGY +    
Sbjct: 22420 IVGIGKPSKVSECYVARDPCDPPGRPEAIIVTRNSVTLQWKKPTYDGGSKITGYIVEKKE 22479

Query: 848   SVEG---SSTELNLPETANSVTLSDLQPGVQYNITIYA------VEENQESTPVVIQQET 898
               EG    ++  N+ +T   VT   L    +Y   + A        E  EST  +  ++ 
Sbjct: 22480 LPEGRWMKASFTNIIDTHFEVT--GLVEDHRYEFRVIARNAAGVFSEPSESTGAITARDE 22537

Query: 899   TGTPRSDTVPSPRDLQFVEVTD---VKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLP 955
                PR    P  +D   V   +   V   I   P  +      +  I  +    +  RL 
Sbjct: 22538 VDPPRISMDPKYKDTIVVHAGESFKVDADIYGKPIPT------IQWIKGDQELSNTARLE 22591

Query: 956   ISRNTFAEVTGLSPGV-----TYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNE-T 1009
             I    FA    +   V      Y  K   V+ G  S  +  +   +   P     ++  T
Sbjct: 22592 IKSTDFATSLSVKDAVRVDSGNYILKAKNVA-GERSVTVNVKVLDRPGPPEGPVVISGVT 22650

Query: 1010  DSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVS 1065
                  + W PP     + I  Y +    T R      +         +  L   +EYT  
Sbjct: 22651 AEKCTLAWKPPLQDGGSDIINYIVERRETSRLVWTVVDANVQTLSCKVTKLLEGNEYTFR 22710

Query: 1066  LVAIKGNQ-----ESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWT-PAPR-----IG 1114
             ++A+         ES         + P +   P  T VT+ ++++ W  PA       +G
Sbjct: 22711 IMAVNKYGVGEPLESEPVVAKNPFVVPDAPKAPEVTTVTKDSMIVVWERPASDGGSEILG 22770

Query: 1115  FKLGVRPSQGGEAPREVTSDSGSIV--VSGLTPGVEYVYTIQVLRD-GQERDAP--IVNK 1169
             + L  R  +G    R      G +   V+GL    +Y + +      G    +P     K
Sbjct: 22771 YVLEKRDKEGIRWTRCHKRLIGELRLRVTGLIENHDYEFRVSAENAAGLSEPSPPSAYQK 22830

Query: 1170  VVTPL---SPPTNLHLEANPDTGVLTVSWERSTTP---DITGYRITTTPTNGQQGNSLEE 1223
                P+    PP N  +     + V  +SW +       +I GY +     +  +      
Sbjct: 22831 ACDPIYKPGPPNNPKVIDITRSSVF-LSWSKPIYDGGCEIQGYIVEKCDVSVGEWTMCTP 22889

Query: 1224  VVHADQSSCTFDNLSPGLEYNVSVYTVKD----DKESVPISDTIIPEVPQLTDLSFVDIT 1279
                 ++++   + L    EYN  +  +      +   VP    I+ E  +  D+      
Sbjct: 22890 PTGINKTNIEVEKLLEKHEYNFRICAINKAGVGEHADVP-GPIIVEEKLEAPDI------ 22942

Query: 1280  DSSIGLRWTPLNSSTIIGYRITVVAAGEGIP----------IFEDFVDSSVGYYTVTGLE 1329
             D  + LR   +N       R+ V   G   P          I +  +      +T   L+
Sbjct: 22943 DLDLELRKI-INIRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTSSFTSLVLD 23001

Query: 1330  PGIDYDISVITLI----NGGESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAPPPSID 1385
                 YD    TL     +G +SA  T+       PP +L+ T I  D++ +TW  PP +D
Sbjct: 23002 NVNRYDSGKYTLTLENSSGTKSAFVTVRVLDTPSPPVNLKVTEITKDSVSITW-EPPLLD 23060

Query: 1386  LTNFLVRYSPVKNE---EDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLR 1442
               + +  Y   K E   +  A +  +   N+  +  L  G  Y   V++  E     P +
Sbjct: 23061 GGSKIKNYIVEKREATRKSYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAENEYGIGLPAQ 23120

Query: 1443  GRQKTGL----DSPTGIDFSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPRE 1494
                   +      P  I   D+T NS ++ W  P     + I  Y +    +H       
Sbjct: 23121 TADPIKVAEVPQPPGKITVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKHSEKWSEC 23180

Query: 1495  DRVPHSRNSITLTNLTPGTEYVVSIVALNGREES-PLLIGQQSTVSDVPRDLEVVAA-TP 1552
              RV   +    +TNLT G EY+  +VA+N +  S P  +       D+  + +V  A + 
Sbjct: 23181 ARVKSLQ--AVITNLTQGEEYLFRVVAVNEKGRSDPRSLAVPIVAKDLVIEPDVKPAFSS 23238

Query: 1553  TSLLISWD----APAVTVRYYRITYGETGGNSPVQEFT---VPGSKSTATIS----GLKP 1601
              S+ +  D     P        IT+ + G   P+++ T   V  S    T+S        
Sbjct: 23239 YSVQVGQDLKIEVPISGRPKPTITWTKDG--LPLKQTTRINVTDSLDLTTLSIKETHKDD 23296

Query: 1602  GVDYTITVYAVTGRGDSPASSKPISINYRTEIDKP----SQMQVTDVQDNSISVKWLP-- 1655
             G  Y ITV  V G+       K  SI   T +DKP      ++  DV   SI++ W P  
Sbjct: 23297 GGQYGITVANVVGQ-------KTASIEIVT-LDKPDPPKGPVKFDDVSAESITLSWNPPL 23348

Query: 1656  --SSSPVTGYRV-----TTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNP 1708
                   +T Y V     TTT  +    T  +T       + +  L+   EY   ++A+N 
Sbjct: 23349 YTGGCQITNYIVQKRDTTTTVWDVVSATVARTT------LKVTKLKTGTEYQFRIFAENR 23402

Query: 1709  SG-----ESQPLVQTAVTNIDRPKGLAF-TDVDVDSIKIAWESPQGQVSRYRVTYSSPED 1762
              G     ES P+V         P G  F T +  DS+ I W  P        + Y     
Sbjct: 23403 YGQSFALESDPIVAQYPYKEPGPPGTPFATAISKDSMVIQWHEPVNNGGSPVIGYHLERK 23462

Query: 1763  GIHELFPAPDGE---EDTA-ELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTD 1818
               + +      +    DT  + Q L  G EY   V A +     +    ++      P D
Sbjct: 23463 ERNSILWTKVNKTIIHDTQFKAQNLEEGIEYEFRVYAENIVGVGKASKNSECYVARDPCD 23522

Query: 1819  LKFT----QVTPTSLSAQWTPP----NVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVV 1870
                T     V    ++ QWT P       +TGY V          MK        +   V
Sbjct: 23523 PPGTPEPIMVKRNEITLQWTKPVYDGGSMITGYIVEKRDLPDGRWMKASFTNVIETQFTV 23582

Query: 1871  SGLMVATKYEVSVYALKDT-LTSRPAQ--GVVTTLENVSPPRRARVTDATETTITISWRT 1927
             SGL    +YE  V A       S+P+   G +T  + V  PR +      +T +  +  T
Sbjct: 23583 SGLTEDQRYEFRVIAKNAAGAISKPSDSTGPITAKDEVELPRISMDPKFRDTIVVNAGET 23642

Query: 1928  KTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQ-PGTDYKIYL------------ 1974
                    F+++A       P    ++ D         +   TD+K  L            
Sbjct: 23643 -------FRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRIDGGQ 23695

Query: 1975  YTLNDN----ARSSPV---VIDASTAIDAPSNLRFLATTPNSLLVSWQPP----RARITG 2023
             Y L  +    ++S PV   V+D     + P  ++    T     ++W PP     + I+ 
Sbjct: 23696 YILRASNVAGSKSFPVNVKVLDRPGPPEGP--VQVTGVTSEKCSLTWSPPLQDGGSDISH 23753

Query: 2024  YIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTV 2083
             Y+++ ++  S     V           +T L  G EY   ++A+      EPL      +
Sbjct: 23754 YVVE-KRETSRLAWTVVASEVVTNSLKVTKLLEGNEYVFRIMAVNKYGVGEPL-ESAPVL 23811

Query: 2084  QKTPFV 2089
              K PFV
Sbjct: 23812 MKNPFV 23817



 Score = 88.2 bits (217), Expect = 9e-17
 Identities = 167/815 (20%), Positives = 297/815 (36%), Gaps = 113/815 (13%)

Query: 1342  INGGESAPTTL-TQQTAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEE 1400
             + G +S P T+       PP   L+ T +  +   + W PP      N        +   
Sbjct: 24786 VGGTKSIPITVKVLDRPGPPEGPLKVTGVTAEKCYLAWNPPLQDGGANISHYIIEKRETS 24845

Query: 1401  DVAELSISPSDNAV--VLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLD------SP 1452
              ++   +S    A+   +T LLPG EY+  V +V +     PL     T  +       P
Sbjct: 24846 RLSWTQVSTEVQALNYKVTKLLPGNEYIFRVMAVNKYGIGEPLESGPVTACNPYKPPGPP 24905

Query: 1453  TGIDFSDITANSFTVHWIAP----RATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTN 1508
             +  + S IT +S  V W  P       I GY +    +      + ++   +   + +T 
Sbjct: 24906 STPEVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDKEGVRWTKCNKKTLTDLRLRVTG 24965

Query: 1509  LTPGTEYVVSIVALN----GREESPLLIGQQSTV---SDVPRDLEVVAATPTSLLISWDA 1561
             LT G  Y   + A N    G    P +  +          P + +V   + +S+ ++W  
Sbjct: 24966 LTEGHSYEFRVAAENAAGVGEPSEPSVFYRACDALYPPGPPSNPKVTDTSRSSVSLAWSK 25025

Query: 1562  PAVTVRYYRITYGETGGNSPVQEFTVPGSKSTA-----------------TISGLKPGVD 1604
             P               G +PV+ + V   ++ A                 T++ LK   +
Sbjct: 25026 PIY------------DGGAPVKGYVVEVKEAAADEWTTCTPPTGLQGKQFTVTKLKENTE 25073

Query: 1605  YTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYR 1664
             Y   + A+   G    ++ P S+  +  I+ P      D++     V  L +S+ +   R
Sbjct: 25074 YNFRICAINSEGVGEPATLPGSVVAQERIEPPEIELDADLR----KVVVLRASATL---R 25126

Query: 1665  VTTTPKNGPGP----TKTKTAGPD--QTEMTIEGLQPTVEYVV-------SVYAQNPSGE 1711
             +  T K  P P     K +    D  Q E+T       ++ V        ++  +N SG 
Sbjct: 25127 LFVTIKGRPEPEVKWEKAEGILTDRAQIEVTSSFTMLVIDNVTRFDSGRYNLTLENNSGS 25186

Query: 1712  SQPLVQTAVTNI-DRPKGLAFTDVDVDSIKIAWESP----QGQVSRYRVTYSSPEDGIHE 1766
                 V   V +    P  L   +V  DS+ ++WE P      +++ Y V         + 
Sbjct: 25187 KTAFVNVRVLDSPSAPVNLTIREVKKDSVTLSWEPPLIDGGAKITNYIVEKRETTRKAYA 25246

Query: 1767  LFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPT----DLKFT 1822
                  +  + T  ++ L+ G  Y   V+A ++     P   T+   +  P      +   
Sbjct: 25247 TI-TNNCTKTTFRIENLQEGCSYYFRVLASNEYGIGLPAETTEPVKVSEPPLPPGRVTLV 25305

Query: 1823  QVTPTSLSAQWTPP----NVQLTGYRVRVTPK--EKTGPMKEINLAPDSSSVVVSGLMVA 1876
              VT  + + +W  P      ++TGY V +  K  EK     ++     +    +SGL   
Sbjct: 25306 DVTRNTATIKWEKPESDGGSKITGYVVEMQTKGSEKWSTCTQVK----TLEATISGLTAG 25361

Query: 1877  TKYEVSVYALKDTLTSRPAQ-GVVTTLENVS-------PPRRARVTDATETTITISWRTK 1928
              +Y   V A+ +   S P Q GV     ++        P     V    +  I + ++ +
Sbjct: 25362 EEYVFRVAAVNEKGRSDPRQLGVPVIARDIEIKPSVELPFHTFNVKAREQLKIDVPFKGR 25421

Query: 1929  TETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQ----PGTDYKIYLYTLNDNARS- 1983
              +    ++ D     GQT  + T      S T+T L        D   Y   ++++A S 
Sbjct: 25422 PQATVNWRKD-----GQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSNSAGSI 25476

Query: 1984  -SPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREV 2038
               P+ I        P  +R    + +S+ +SW PP      +I+ YI++ ++  S    +
Sbjct: 25477 TVPITIIVLDRPGPPGPIRIDEVSCDSITISWNPPEYDGGCQISNYIVEKKETTSTTWHI 25536

Query: 2039  VPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKS 2073
             V +     T   I  L  G+EY   V A     KS
Sbjct: 25537 VSQ-AVARTSIKIVRLTTGSEYQFRVCAENRYGKS 25570



 Score = 86.3 bits (212), Expect = 3e-16
 Identities = 342/1651 (20%), Positives = 590/1651 (35%), Gaps = 266/1651 (16%)

Query: 628   IQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISI 684
             + W+ P+    S I+ +I+  R    +  W++  I    +   I GL  G  Y+ ++I+ 
Sbjct: 15215 LNWSDPEDDGGSEITGFIIE-RKDAKMHTWRQP-IETERSKCDITGLLEGQEYKFRVIAK 15272

Query: 685   QQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWV--- 741
              ++G                PV    +        P      + TE T S+  + W    
Sbjct: 15273 NKFG-------------CGPPVEIGPILAVDPLGPPTSPERLTYTERTKSTITLDWKEPR 15319

Query: 742   -SASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQS 800
              +    + G+ +E    ++ D  +        TS  + +L   + Y   V  ++E GE  
Sbjct: 15320 SNGGSPIQGYIIEKRRHDKPDFERVNKRLCPTTSFLVENLDEHQMYEFRVKAVNEIGESE 15379

Query: 801   LILSTSQTTAPDAPPDPTVD---QVDDTSIVVRWSRP---QAPITGYRIVYSPSVEGSST 854
               L  +     D  P PT+     V   +I V+   P    A +TG  +   P +E S  
Sbjct: 15380 PSLPLNVVIQDDEVP-PTIKLRLSVRGDTIKVKAGEPVHIPADVTGLPM---PKIEWSKN 15435

Query: 855   E--LNLPETANSVTLSDLQPG-VQYNITI-YAVEENQESTPVVIQQETTGTPRS------ 904
             E  +  P  A  +T  ++     +  ++I  AV E++ +  V          R+      
Sbjct: 15436 ETVIEKPTDALQITKEEVSRSEAKTELSIPKAVREDKGTYTVTASNRLGSVFRNVHVEVY 15495

Query: 905   DTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPGEHGQRLPISRNT 960
             D    PR+L   ++      + W  P     S +T Y +D    +      + +    NT
Sbjct: 15496 DRPSPPRNLAVTDIKAESCYLTWDAPLDNGGSEITHYVIDKRDASRKKAEWEEVT---NT 15552

Query: 961   FAE----VTGLSPGVTYYFKV-----FAVSHGRESKPLTAQQTTKLDAPTNL-QFVNETD 1010
               E    +  L P   Y F+V     + +S   +S  +  Q   +L  P    + +  T 
Sbjct: 15553 AVEKRYGIWKLIPNGQYEFRVRAVNKYGISDECKSDKVVIQDPYRLPGPPGKPKVLARTK 15612

Query: 1011  STVLVRWTPP----RAQITGYRLTVGLTRRGQPRQY----------NVGPSVSKYPLRNL 1056
              ++LV WTPP     + ITGY     L +R +   Y           VG    ++ +  L
Sbjct: 15613 GSMLVSWTPPLDNGGSPITGY----WLEKREEGSPYWSRVSRAPITKVGLKGVEFNVPRL 15668

Query: 1057  QPASEYTVSLVAIKG------NQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPA 1110
                 +Y    +AI        ++ S           PG    P   + T+++I + W P 
Sbjct: 15669 LEGVKYQFRAMAINAAGIGPPSEPSDPEVAGDPIFPPGPPSCPEVKDKTKSSISLGWKPP 15728

Query: 1111  PRIGFKLGVRPSQG--GEAPREVTSD------------SGSIVVSGLTPGVEYVYTIQVL 1156
                  K G  P +G   E   E T+D            +   VV  L    +Y + ++ +
Sbjct: 15729 A----KDGGSPIKGYIVEMQEEGTTDWKRVNEPDKLITTCECVVPNLKELRKYRFRVKAV 15784

Query: 1157  RD-GQERDAPIVNKV-VTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPT- 1213
              + G+   +    ++  T +     + ++      ++  +  +   P +   R T   + 
Sbjct: 15785 NEAGESEPSDTTGEIPATDIQEEPEVFIDIGAQDCLVCKAGSQIRIPAVIKGRPTPKSSW 15844

Query: 1214  --NGQQGNSLEEVVH---ADQSSCTFDNLSPGL----------EYNVSVYTVKDDKES-- 1256
               +G+   ++++ VH    D    T +N S  +          +Y+++       K +  
Sbjct: 15845 EFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECKRSHTGKYSITAKNKAGQKTANC 15904

Query: 1257  -VPISDTIIPEVPQLTDLSFVDITDSSIGLRWTPLN---SSTIIGYRITVVAAGEGIPIF 1312
              V + D  +P  P+  DL   DIT  S  L W   +      I GY I      +G    
Sbjct: 15905 RVKVMD--VPGPPK--DLKVSDITRGSCRLSWKMPDDDGGDRIKGYVIEKRTI-DGKAWT 15959

Query: 1313  EDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAV-------PPPTDLR 1365
             +   D     + V  L     Y   V      G   P    Q+T          PP  L+
Sbjct: 15960 KVNPDCGSTTFVVPDLLSEQQYFFRVRAENRFGIGPPVETIQRTTARDPIYPPDPPIKLK 16019

Query: 1366  FTNIGPDTMRVTWAPPPS---IDLTNFLVR---YSPVK---------NEEDVAELSISPS 1410
                I  +T+ ++W PP +     +T+++V    + P           N+ DV EL  +  
Sbjct: 16020 IGLITKNTVHLSWKPPKNDGGSPVTHYIVECLAWDPTGTKKEAWRQCNKRDVEELQFTVE 16079

Query: 1411  DNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGL---DSPTGIDFSDI--TANSF 1465
             D       L+ G EY   V +V     S P            D P  ID  +        
Sbjct: 16080 D-------LVEGGEYEFRVKAVNAAGVSKPSATVGPCDCQRPDMPPSIDLKEFMEVEEGT 16132

Query: 1466  TVHWIA-----PRATITGYRIRH----------HPEHFSGRPREDR----VPHSRNSITL 1506
              V+ +A     P  T+T ++             +  H +    +D     +P SR S T 
Sbjct: 16133 NVNIVAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDT- 16191

Query: 1507  TNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAP---- 1562
                     Y ++ V   G     + +            ++  + +   + +SW  P    
Sbjct: 16192 ------GLYTITAVNNLGTASKEMRLNVLGRPGPPVGPIKFESVSADQMTLSWFPPKDDG 16245

Query: 1563  AVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRG-DSPAS 1621
                +  Y I   E    + V   + P  + T TI  L  G +Y   + A    G   P  
Sbjct: 16246 GSKITNYVIEKREANRKTWVHVSSEP-KECTYTIPKLLEGHEYVFRIMAQNKYGIGEPLD 16304

Query: 1622  SKP-ISINYRTEIDKPSQMQVTDVQDNSISVKW----LPSSSPVTGYRV---TTTPKN-- 1671
             S+P  + N  +    P +  V+ V  NS++V W        SPVTGY +    TT K   
Sbjct: 16305 SEPETARNLFSVPGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPVTGYWLEMKDTTSKRWK 16364

Query: 1672  --GPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSG---ESQPLVQTAVTNIDRP 1726
                  P K  T G       + GL    +Y   VYA N +G    S P       +   P
Sbjct: 16365 RVNRDPIKAMTLG---VSYKVTGLIEGSDYQFRVYAINAAGVGPASLPSDPATARDPIAP 16421

Query: 1727  KGLAF---TDVDVDSIKIAWESP----QGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAE 1779
              G  F   TD    S  + W  P      +V+ Y V Y   E+G  E     D E    +
Sbjct: 16422 PGPPFPKVTDWTKSSADLEWSPPLKDGGSKVTGYIVEYK--EEGKEEWEKGKDKEVRGTK 16479

Query: 1780  L--QGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTP-TSLSAQWTPP 1836
             L   GL+ G+ Y   V A++     +P  G  +  I    ++K   V+P   L A     
Sbjct: 16480 LVVTGLKEGAFYKFRVRAVNIAGIGEP--GEVTDVI----EMKDRLVSPDLQLDASVRDR 16533

Query: 1837  NVQLTGYRVRV-------TPKEKTGPMKEINLAPDSS--SVVVSGLMVATKYEVS---VY 1884
              V   G  +R+        P   T  M E  L  +++  +  +S  MV    + S   VY
Sbjct: 16534 IVVHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEATIETTAISSSMVIKNCQRSHQGVY 16593

Query: 1885  AL--KDTLTSRPAQGVVTTLENVSPPRRARVT-DATETTITISWRTKTE----TITGFQV 1937
             +L  K+    R    +V  L+   P     +  + T  +  ++W +  +     IT + +
Sbjct: 16594 SLLAKNEAGERKKTIIVDVLDVPGPVGTPFLAHNLTNESCKLTWFSPEDDGGSPITNYVI 16653

Query: 1938  DAVPANGQ--TPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLND-------NARSSPVVI 1988
             +   ++ +  TP+  T+    ++ T+ GL  G  Y   +   N            + V+ 
Sbjct: 16654 EKRESDRRAWTPVTYTVTR--QNATVQGLIQGKAYFFRIAAENSIGMGPFVETSEALVIR 16711

Query: 1989  DASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREVVPRPRP 2044
             +  T  + P +L     T N++ ++W PP+    + I  Y+++    G+     V     
Sbjct: 16712 EPITVPERPEDLEVKEVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEKFHKVTNDNL 16771

Query: 2045  GVTEATITGLEPGTEYTIYVIALKNNQKSEP 2075
                + T+ GL+ G  Y   V A+    + +P
Sbjct: 16772 LSRKYTVKGLKEGDTYEYRVSAVNIVGQGKP 16802



 Score = 84.3 bits (207), Expect = 1e-15
 Identities = 134/644 (20%), Positives = 244/644 (37%), Gaps = 79/644 (12%)

Query: 1512  GTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAP----AVTVR 1567
             G +Y++    + G +  P+ +            ++V   T     ++W  P       + 
Sbjct: 23693 GGQYILRASNVAGSKSFPVNVKVLDRPGPPEGPVQVTGVTSEKCSLTWSPPLQDGGSDIS 23752

Query: 1568  YYRITYGETGGNSPVQEFTVPGSK---STATISGLKPGVDYTITVYAVTGRG-DSPASSK 1623
             +Y +   ET   +    +TV  S+   ++  ++ L  G +Y   + AV   G   P  S 
Sbjct: 23753 HYVVEKRETSRLA----WTVVASEVVTNSLKVTKLLEGNEYVFRIMAVNKYGVGEPLESA 23808

Query: 1624  PISINYRTEID-KPSQMQVTDVQDNSISVKW-LPSS---SPVTGYRVTTTPKNGPGPTKT 1678
             P+ +     +   P  ++VT++  +S++V W  P S   S + GY V    ++G    K 
Sbjct: 23809 PVLMKNPFVLPGPPKSLEVTNIAKDSMTVCWNRPDSDGGSEIIGYIVEKRDRSGIRWIKC 23868

Query: 1679  KTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTA-------VTNIDRPKGLAF 1731
                      + + GL    EY   V A+N +G  +P   T        V     P     
Sbjct: 23869 NKRRITDLRLRVTGLTEDHEYEFRVSAENAAGVGEPSPATVYYKACDPVFKPGPPTNAHI 23928

Query: 1732  TDVDVDSIKIAWESP----QGQVSRYRVTYSSPEDGIHELFPAPDGEEDTA-ELQGLRPG 1786
              D   +SI +AW  P      ++  Y V     ++   ++     G   T  E+  L   
Sbjct: 23929 VDTTKNSITLAWGKPIYDGGSEILGYVVEICKADEEEWQIVTPQTGLRVTRFEISKLTEH 23988

Query: 1787  SEYTVSVVALHDDMESQPLIGT-QSTAIPAPTDLKFTQVTPT-SLSAQWTPPNVQLTGYR 1844
              EY + V AL+        +G  ++T++P     +     P   L ++     V   G  
Sbjct: 23989 QEYKIRVCALNK-------VGLGEATSVPGTVKPEDKLEAPELDLDSELRKGIVVRAGGS 24041

Query: 1845  VRVTPKEKTGPMKEINLAPD----SSSVVVSGLMVATKYEVS----------VYALKDTL 1890
              R+    K  P  EI  + +    +  V +   +  T+  +           +  L+++ 
Sbjct: 24042 ARIHIPFKGRPTPEITWSREEGEFTDKVQIEKGVNYTQLSIDNCDRNDAGKYILKLENSS 24101

Query: 1891  TSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKT----ETITGFQVDAVPANGQT 1946
              S+ A   V  L+   PP+   V +  + +  + W          +  + +D   +  + 
Sbjct: 24102 GSKSAFVTVKVLDTPGPPQNLAVKEVRKDSAFLVWEPPIIDGGAKVKNYVIDKRESTRKA 24161

Query: 1947  PIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPV-VIDASTAIDAPS-----NL 2000
                 + K    S+ +  L  G  Y   +   N+     PV  +DA  A + PS      L
Sbjct: 24162 YANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFGVGVPVETVDAVKAAEPPSPPGKVTL 24221

Query: 2001  RFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEP 2056
               ++ T  SL+  W+ P     +R+ GY+++ +  G+    +V   +  V  A +TGL  
Sbjct: 24222 TDVSQTSASLM--WEKPEHDGGSRVLGYVVEMQPKGTEKWSIVAESK--VCNAVVTGLSS 24277

Query: 2057  GTEYTIYVIALKNNQKSE------PLIGRKKTVQ---KTPFVTH 2091
             G EY   V A     KS+      P+I +  T+Q   K PF T+
Sbjct: 24278 GQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKLPFNTY 24321



 Score = 83.6 bits (205), Expect = 2e-15
 Identities = 320/1617 (19%), Positives = 567/1617 (35%), Gaps = 238/1617 (14%)

Query: 628   IQWNAPQPS---HISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISI 684
             + WN P  +    I+ YI++ R   +   W   +      +  +  LK G  Y+ ++ + 
Sbjct: 23342 LSWNPPLYTGGCQITNYIVQKRDTTTTV-WDVVSATVARTTLKVTKLKTGTEYQFRIFAE 23400

Query: 685   QQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSAS 744
              +YG       D        P+ +     E  P     AT+     I+  S V+ W    
Sbjct: 23401 NRYGQSFALESD--------PIVAQYPYKEPGPPGTPFATA-----ISKDSMVIQWHEPV 23447

Query: 745   DTVSGFRVEYELS-EEGDEPQYLDLPSTA---TSVNIPDLLPG-----RKYIVNVYQISE 795
             +      + Y L  +E +   +  +  T    T     +L  G     R Y  N+  + +
Sbjct: 23448 NNGGSPVIGYHLERKERNSILWTKVNKTIIHDTQFKAQNLEEGIEYEFRVYAENIVGVGK 23507

Query: 796   DGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ----APITGYRIVYSPSVEG 851
               + S          P   P+P +  V    I ++W++P     + ITGY +      +G
Sbjct: 23508 ASKNSECYVARDPCDPPGTPEPIM--VKRNEITLQWTKPVYDGGSMITGYIVEKRDLPDG 23565

Query: 852   ---SSTELNLPETANSVTLSDLQPGVQYNITIYA------VEENQESTPVVIQQETTGTP 902
                 ++  N+ ET    T+S L    +Y   + A      + +  +ST  +  ++    P
Sbjct: 23566 RWMKASFTNVIET--QFTVSGLTEDQRYEFRVIAKNAAGAISKPSDSTGPITAKDEVELP 23623

Query: 903   RSDTVPSPRDLQFVEVTDV-----------KVTIMWTPPESAVTGYRVDVIPVNLPGEHG 951
             R    P  RD   V   +              TI W   +  +              E  
Sbjct: 23624 RISMDPKFRDTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEI--------------EES 23669

Query: 952   QRLPISRNTFAEVTGLSPGVT-----YYFKVFAVSHGRESKPLTAQQTTKLDAPTN-LQF 1005
              R  I    F  +  +   +      Y  +   V+ G +S P+  +   +   P   +Q 
Sbjct: 23670 ARCEIKNTDFKALLIVKDAIRIDGGQYILRASNVA-GSKSFPVNVKVLDRPGPPEGPVQV 23728

Query: 1006  VNETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASE 1061
                T     + W+PP     + I+ Y +    T R            +   +  L   +E
Sbjct: 23729 TGVTSEKCSLTWSPPLQDGGSDISHYVVEKRETSRLAWTVVASEVVTNSLKVTKLLEGNE 23788

Query: 1062  YTVSLVAIK--GNQESPKATGVFTT---LQPGSSIPPYNTEVT---ETTIVITWTPAPR- 1112
             Y   ++A+   G  E  ++  V      + PG   PP + EVT   + ++ + W      
Sbjct: 23789 YVFRIMAVNKYGVGEPLESAPVLMKNPFVLPG---PPKSLEVTNIAKDSMTVCWNRPDSD 23845

Query: 1113  -----IGFKLGVRPSQGGE----APREVTSDSGSIVVSGLTPGVEYVYTIQVLRD---GQ 1160
                  IG+ +  R   G        R +T     + V+GLT   EY + +        G+
Sbjct: 23846 GGSEIIGYIVEKRDRSGIRWIKCNKRRITDLR--LRVTGLTEDHEYEFRVSAENAAGVGE 23903

Query: 1161  ERDAPIVNKVVTPL---SPPTNLHLEANPDTGVLTVSWERSTTP---DITGYRITTTPTN 1214
                A +  K   P+    PPTN H+  +     +T++W +       +I GY +     +
Sbjct: 23904 PSPATVYYKACDPVFKPGPPTNAHI-VDTTKNSITLAWGKPIYDGGSEILGYVVEICKAD 23962

Query: 1215  GQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDK--ESVPISDTIIPE----VP 1268
              ++   +        +      L+   EY + V  +      E+  +  T+ PE     P
Sbjct: 23963 EEEWQIVTPQTGLRVTRFEISKLTEHQEYKIRVCALNKVGLGEATSVPGTVKPEDKLEAP 24022

Query: 1269  QLTDLSFVDITDSSIGLRWTPLNSSTII--GYRITVVAAGEGIPIFEDFVDSSVGYYT-V 1325
             +L DL              + L    ++  G    +    +G P  E       G +T  
Sbjct: 24023 EL-DLD-------------SELRKGIVVRAGGSARIHIPFKGRPTPEITWSREEGEFTDK 24068

Query: 1326  TGLEPGIDYD---------------ISVITLINGGESAPTTLTQQTAVPPPTDLRFTNIG 1370
               +E G++Y                I  +   +G +SA  T+       PP +L    + 
Sbjct: 24069 VQIEKGVNYTQLSIDNCDRNDAGKYILKLENSSGSKSAFVTVKVLDTPGPPQNLAVKEVR 24128

Query: 1371  PDTMRVTWAPPPSIDLTNFLVRYSPVKNEED---VAELSISPSDNAVVLTNLLPGTEYVV 1427
              D+  + W PP  ID    +  Y   K E      A +S   S  +  + NL  G  Y  
Sbjct: 24129 KDSAFLVWEPP-IIDGGAKVKNYVIDKRESTRKAYANVSSKCSKTSFKVENLTEGAIYYF 24187

Query: 1428  SVSSVYEQHESTPLR---GRQKTGLDSPTG-IDFSDITANSFTVHWIAPR----ATITGY 1479
              V +  E     P+      +     SP G +  +D++  S ++ W  P     + + GY
Sbjct: 24188 RVMAENEFGVGVPVETVDAVKAAEPPSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLGY 24247

Query: 1480  RIRHHPEHFSGRPREDRVPHSRN-SITLTNLTPGTEYVVSIVALNGREES-PLLIGQQST 1537
              +   P+   G  +   V  S+  +  +T L+ G EY   + A N + +S P ++G    
Sbjct: 24248 VVEMQPK---GTEKWSIVAESKVCNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVI 24304

Query: 1538  VSDVPRDLEVVAATPTSLL-----ISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKS 1592
               D+     +     T  +     +  + P +      I++ + G   P+++ T    + 
Sbjct: 24305 AKDLTIQPSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDG--EPLKQTTRVNVEE 24362

Query: 1593  TAT--ISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKP-SQMQVTDVQDNSI 1649
             TAT  +  +K G       Y VT    +  +++ +S+    +   P   ++  +V  + +
Sbjct: 24363 TATSTVLHIKEGNKDDFGKYTVTATNSAGTATENLSVIVLEKPGPPVGPVRFDEVSADFV 24422

Query: 1650  SVKWLPSS----SPVTGYRV-----TTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYV 1700
              + W P +      ++ Y V     TTT  +    T  +T       + I  L+   EY 
Sbjct: 24423 VISWEPPAYTGGCQISNYIVEKRDTTTTTWHMVSATVARTT------IKITKLKTGTEYQ 24476

Query: 1701  VSVYAQNPSGESQPLVQTAVT-----NIDRPKGLAF-TDVDVDSIKIAWESPQGQVSRYR 1754
               ++A+N  G+S PL   AV          P G  F T +  D + + W  P        
Sbjct: 24477 FRIFAENRYGKSAPLDSKAVIVQYPFKEPGPPGTPFVTSISKDQMLVQWHEPVNDGGTKI 24536

Query: 1755  VTYSSPEDGIHELF-------PAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIG 1807
             + Y   +   + +        P  D +  T    GL  G EY   V A +     +P   
Sbjct: 24537 IGYHLEQKEKNSILWVKLNKTPIQDTKFKTT---GLDEGLEYEFKVSAENIVGIGKPSKV 24593

Query: 1808  TQSTAIPAPTDL----KFTQVTPTSLSAQWTPP----NVQLTGYRVRVTPKEKTGPMKEI 1859
             ++      P D     +   +T  +++ +W  P      ++TGY V          MK  
Sbjct: 24594 SECFVARDPCDPPGRPEAIVITRNNVTLKWKKPAYDGGSKITGYIVEKKDLPDGRWMKAS 24653

Query: 1860  NLAPDSSSVVVSGLMVATKYEVSVYALKDTLT-SRPAQ--GVVTTLENVSPPRRAR---- 1912
                   +   VSGL+   +YE  V A       S P+   G +T  + +  P  +     
Sbjct: 24654 FTNVLETEFTVSGLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARDEIDAPNASLDPKY 24713

Query: 1913  ----VTDATET-TITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQP- 1966
                 V  A ET  +    R K      +  D      +T  +  IK  ++  T+      
Sbjct: 24714 KDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELE-ETAARMEIKSTIQKTTLVVKDCI 24772

Query: 1967  GTDYKIYLYTLND--NARSSPVVIDASTAIDAPSN-LRFLATTPNSLLVSWQPPR----A 2019
              TD   Y+  L++    +S P+ +        P   L+    T     ++W PP     A
Sbjct: 24773 RTDGGQYILKLSNVGGTKSIPITVKVLDRPGPPEGPLKVTGVTAEKCYLAWNPPLQDGGA 24832

Query: 2020  RITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPL 2076
              I+ YII+  +        V      +    +T L PG EY   V+A+      EPL
Sbjct: 24833 NISHYIIEKRETSRLSWTQVSTEVQALNYK-VTKLLPGNEYIFRVMAVNKYGIGEPL 24888



 Score = 82.4 bits (202), Expect = 5e-15
 Identities = 130/589 (22%), Positives = 217/589 (36%), Gaps = 70/589 (11%)

Query: 1596  ISGLKPGVDYTITVYAVTGRG-DSPASSKPI-SINYRTEIDKPSQMQVTDVQDNSISVKW 1653
             ++ L  G +YT  + AV   G   P  S+P+ + N     D P   +VT V  +S+ V W
Sbjct: 22698 VTKLLEGNEYTFRIMAVNKYGVGEPLESEPVVAKNPFVVPDAPKAPEVTTVTKDSMIVVW 22757

Query: 1654  -LPSS---SPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPS 1709
               P+S   S + GY +    K G   T+       +  + + GL    +Y   V A+N +
Sbjct: 22758 ERPASDGGSEILGYVLEKRDKEGIRWTRCHKRLIGELRLRVTGLIENHDYEFRVSAENAA 22817

Query: 1710  GESQPLVQTA-------VTNIDRPKGLAFTDVDVDSIKIAWESP----QGQVSRYRVTYS 1758
             G S+P   +A       +     P      D+   S+ ++W  P      ++  Y V   
Sbjct: 22818 GLSEPSPPSAYQKACDPIYKPGPPNNPKVIDITRSSVFLSWSKPIYDGGCEIQGYIVEKC 22877

Query: 1759  SPEDGIHELFPAPDGEEDT-AELQGLRPGSEYTVSVVAL-------HDDMESQPLIGTQS 1810
                 G   +   P G   T  E++ L    EY   + A+       H D+    ++  + 
Sbjct: 22878 DVSVGEWTMCTPPTGINKTNIEVEKLLEKHEYNFRICAINKAGVGEHADVPGPIIVEEKL 22937

Query: 1811  TAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEK----TGPMKEINLAPDSS 1866
              A     DL+  ++                   + R TP+ K     G +++  +   +S
Sbjct: 22938 EAPDIDLDLELRKIINIRAGGSLR----LFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTS 22993

Query: 1867  SVVVSGLMVATKYEVSVY--ALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITIS 1924
             S     L    +Y+   Y   L+++  ++ A   V  L+  SPP   +VT+ T+ +++I+
Sbjct: 22994 SFTSLVLDNVNRYDSGKYTLTLENSSGTKSAFVTVRVLDTPSPPVNLKVTEITKDSVSIT 23053

Query: 1925  WRTKT----ETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDN 1980
             W          I  + V+   A  ++           S+ I  LQ G  Y   +   N+ 
Sbjct: 23054 WEPPLLDGGSKIKNYIVEKREATRKSYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAENEY 23113

Query: 1981  ARSSPV----VIDASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPG 2032
                 P      I  +     P  +     T NS+ +SW  P     ++I  YI++ +   
Sbjct: 23114 GIGLPAQTADPIKVAEVPQPPGKITVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKH 23173

Query: 2033  SPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQKTPFVTHP 2092
             S       R +    +A IT L  G EY   V+A+    +S+P       V K   V  P
Sbjct: 23174 SEKWSECARVKS--LQAVITNLTQGEEYLFRVVAVNEKGRSDPRSLAVPIVAK-DLVIEP 23230

Query: 2093  GYDTGNGIQLPGTSGQQPSVGQQMIFEEHGFRRTTPPTTATPIRHRPRP 2141
                       P  S     VGQ +  E              PI  RP+P
Sbjct: 23231 DVK-------PAFSSYSVQVGQDLKIE-------------VPISGRPKP 23259



 Score = 78.2 bits (191), Expect = 9e-14
 Identities = 285/1428 (19%), Positives = 490/1428 (34%), Gaps = 237/1428 (16%)

Query: 690   QEVTRFDFTTTSTST---------------PVTSNTVTGET-------------TPFSPL 721
             ++  R +F TT+TST               P+T+  + GE               P  P+
Sbjct: 21107 KQTQRVNFETTATSTILNINECVRSDSGPYPLTARNIVGEVGDVITIQVHDIPGPPTGPI 21166

Query: 722   VATSESVTEITASSFVVSWVSASDT----VSGFRVEYELSEEGDEPQYLDLPSTA--TSV 775
                     E+++     SW    +     +S + VE     + D   +++L +T   T+ 
Sbjct: 21167 -----KFDEVSSDFVTFSWDPPENDGGVPISNYVVEMR---QTDSTTWVELATTVIRTTY 21218

Query: 776   NIPDLLPGRKYIVNV-----YQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVR 830
                 L  G +Y   V     Y +      + I++      P  P  P V  V   S+ + 
Sbjct: 21219 KATRLTTGLEYQFRVKAQNRYGVGPGITSACIVANYPFKVPGPPGTPQVTAVTKDSMTIS 21278

Query: 831   WSRPQA----PITGYRIVYSPSVEGSSTELNLPETANSVTL-------SDLQPGVQYNIT 879
             W  P +    PI GY       VE       L +T +   +       S L  G+ Y   
Sbjct: 21279 WHEPLSDGGSPILGYH------VERKERNGILWQTVSKALVPGNIFKSSGLTDGIAYEFR 21332

Query: 880   IYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESA----VT 935
             + A     +S P    +        D    P  L     T   VT+ W  PE      +T
Sbjct: 21333 VIAENMAGKSKPSKPSEPMLALDPIDPPGKPVPLNITRHT---VTLKWAKPEYTGGFKIT 21389

Query: 936   GYRVDVIPVNLPGEHGQRLPISR---NTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQ 992
              Y V+    +LP     +   S    N F  V+GL+    Y F+V A +      P +  
Sbjct: 21390 SYIVE--KRDLPNGRWLKANFSNILENEFT-VSGLTEDAAYEFRVIAKNAAGAISPPSEP 21446

Query: 993   QTT-----KLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPS 1047
                      ++AP     V   D+ +L            +RL   ++ R  P        
Sbjct: 21447 SDAITCRDDVEAPKIKVDVKFKDTVILKAGE-------AFRLEADVSGRPPPTMEWSKDG 21499

Query: 1048  VSKYPLRNLQ-PASEYTVSLVAIKGNQESPKATGVFTTLQPGSSI-------------PP 1093
                     L+   ++++ +LV  K +          T   PG                PP
Sbjct: 21500 KELEGTAKLEIKIADFSTNLVN-KDSTRRDSGAYTLTATNPGGFAKHIFNVKVLDRPGPP 21558

Query: 1094  YN----TEVTETTIVITW-TPAPRIGFKLGVRPSQGGEAPREVTSDSGSIV------VSG 1142
                   TEVT    V++W  P    G K+     Q  E  R   ++  S V      V+ 
Sbjct: 21559 EGPLAVTEVTSEKCVLSWFPPLDDGGAKIDHYIVQKRETSRLAWTNVASEVQVTKLKVTK 21618

Query: 1143  LTPGVEYVYTIQVLRD---GQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLT-----VS 1194
             L  G EY++ +  +     G+  ++  V   V P  PP       NP+   +T     V 
Sbjct: 21619 LLKGNEYIFRVMAVNKYGVGEPLESEPV-LAVNPYGPPDP---PKNPEVTTITKDSMVVC 21674

Query: 1195  WERSTTP---DITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVK 1251
             W    +    +I  Y +      GQ+     +    D        L+ G EY   +    
Sbjct: 21675 WGHPDSDGGSEIINYIVERRDKAGQRWIKCNKKTLTDLRY-KVSGLTEGHEYEFRIMAEN 21733

Query: 1252  DDKESVP--------ISDTIIPEVPQLTDLSFVDITDSSIGLRWT-PL--NSSTIIGYRI 1300
                 S P          DT+    P   +   +D + SSI + W  P+    S I GY +
Sbjct: 21734 AAGISAPSPTSPFYKACDTVFKPGPP-GNPRVLDTSRSSISIAWNKPIYDGGSEITGYMV 21792

Query: 1301  TVVAAGEGI-PIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAP-----TTLTQ 1354
              +    E    I           YT+TGL    +Y I +  + + G   P     T   +
Sbjct: 21793 EIALPEEDEWQIVTPPAGLKATSYTITGLTENQEYKIRIYAMNSEGLGEPALVPGTPKAE 21852

Query: 1355  QTAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNE------------EDV 1402
                +PP  +L       D  +V      +I     L  + P+K              E +
Sbjct: 21853 DRMLPPEIEL-----DADLRKVV-----TIRACCTLRLFVPIKGRPAPEVKWARDHGESL 21902

Query: 1403  AELSISPSDNAVVL----TNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFS 1458
              + SI  + +  +L     N     +Y+++V +     +S  +  R       P  +   
Sbjct: 21903 DKASIESTSSYTLLIVGNVNRFDSGKYILTVENS-SGSKSAFVNVRVLDTPGPPQDLKVK 21961

Query: 1459  DITANSFTVHWIAPRATITGYRIRHH--PEHFSGRPREDRVPHS--RNSITLTNLTPGTE 1514
             ++T  S T+ W  P     G +I+++   +  S R     V  +  + S  +  L  G  
Sbjct: 21962 EVTKTSVTLTWDPPLLD-GGSKIKNYIVEKRESTRKAYSTVATNCHKTSWKVDQLQEGCS 22020

Query: 1515  YVVSIVALNGREES-PLLIGQQSTVSD---VPRDLEVVAATPTSLLISWDAP----AVTV 1566
             Y   ++A N      P    +    S+    P  + ++  T  S+ +SW+ P       +
Sbjct: 22021 YYFRVLAENEYGIGLPAETAESVKASERPLPPGKITLMDVTRNSVSLSWEKPEHDGGSRI 22080

Query: 1567  RYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPIS 1626
               Y +     G +      TV  ++  ATI+GL  G +Y+  V A   +G S      + 
Sbjct: 22081 LGYIVEMQTKGSDKWATCATVKVTE--ATITGLIQGEEYSFRVSAQNEKGISDPRQLSVP 22138

Query: 1627  INYRTEIDKPS------QMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKT 1680
             +  +  +  P+         V   +D  + V ++   +P   +     P       +T  
Sbjct: 22139 VIAKDLVIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLK-----QTTR 22193

Query: 1681  AGPDQTE----MTIEGL--QPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKG--LAFT 1732
                + TE    +TI+    +    YVV +   N +GE+   +   V +   P    +   
Sbjct: 22194 VNAESTENNSLLTIKDACREDVGHYVVKL--TNSAGEAIETLNVIVLDKPGPPTGPVKMD 22251

Query: 1733  DVDVDSIKIAWESPQ----GQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSE 1788
             +V  DSI ++W  P+      ++ Y V          ++  A      T +   L+ G E
Sbjct: 22252 EVTADSITLSWGPPKYDGGSSINNYIVEKRDTSTTTWQIVSATVART-TIKACRLKTGCE 22310

Query: 1789  YTVSVVALH-----DDMESQPLIGTQSTAIPAPTDLKFTQVTPT-SLSAQWTPP----NV 1838
             Y   + A +       + S+P +      +P P       ++   S+  QW  P      
Sbjct: 22311 YQFRIAAENRYGKSTYLNSEPTVAQYPFKVPGPPGTPVVTLSSRDSMEVQWNEPISDGGS 22370

Query: 1839  QLTGYRVRVTPKEKTGPM-KEINLAP-DSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQ 1896
             ++ GY +    KE+   +  ++N  P   +    +GL    +YE  V A       +P++
Sbjct: 22371 RVIGYHLE--RKERNSILWVKLNKTPIPQTKFKTTGLEEGVEYEFRVSAENIVGIGKPSK 22428

Query: 1897  --GVVTTLENVSPPRRARVTDATETTITISWRTKT----ETITGFQVD 1938
                     +   PP R      T  ++T+ W+  T      ITG+ V+
Sbjct: 22429 VSECYVARDPCDPPGRPEAIIVTRNSVTLQWKKPTYDGGSKITGYIVE 22476



 Score = 75.1 bits (183), Expect = 8e-13
 Identities = 286/1351 (21%), Positives = 472/1351 (34%), Gaps = 234/1351 (17%)

Query: 797   GEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ----APITGYRIVYSPSVEGS 852
             G +++ +       P  P D  V ++   S  + W  P     + IT Y +         
Sbjct: 17296 GSKTVSVKVLVLDKPGPPRDLEVSEIRKDSCYLTWKEPLDDGGSVITNYVVERRDVASAQ 17355

Query: 853   STELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRD 912
              + L+      S     L  G QY   + A  +      V   +             P+D
Sbjct: 17356 WSPLSATSKKKSHFAKHLNEGNQYLFRVAAENQYGRGPFVETPKPIKALDPLHPPGPPKD 17415

Query: 913   LQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPVNLPGEHGQRLPISRNTFAE----V 964
             L  V+V   +V+++W  P+    S +TGY V+        E G +  I   T       V
Sbjct: 17416 LHHVDVDKTEVSLVWNKPDRDGGSPITGYLVEY------QEEGTQDWIKFKTVTNLECVV 17469

Query: 965   TGLSPGVTYYFKVFA---VSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPR 1021
             TGL  G TY F+V A   V  G     +  +   KL  P+    V   +  V+   T  R
Sbjct: 17470 TGLQQGKTYRFRVKAENIVGLGLPDTTIPIECQEKLVPPSVELDVKLIEGLVVKAGTTVR 17529

Query: 1022  --AQITGYRL-TVGLTRRGQPRQYNVGPSV------SKYPLRNL--QPASEYTVSLVAIK 1070
               A I G  + T   T  G   + +   +V      S   ++N   +   EY +++    
Sbjct: 17530 FPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEYQITV---- 17585

Query: 1071  GNQESPKATGVFTTLQ--PGSSIPPYNT-EVTETTIVITWTPAPRIGFKLGVRPSQGGEA 1127
              N    K   V  T+   PG    P N  +VT   + I+W P           P   G +
Sbjct: 17586 SNAAGSKTVAVHLTVLDVPGPPTGPINILDVTPEHMTISWQP-----------PKDDGGS 17634

Query: 1128  P--------REVTSDSGSIVVSG----------LTPGVEYVYTIQV---LRDGQERDA-P 1165
             P        ++   D+  +V SG          L  G EYV+ ++    +  G   D+ P
Sbjct: 17635 PVINYIVEKQDTRKDTWGVVSSGSSKTKLKIPHLQKGCEYVFRVRAENKIGVGPPLDSTP 17694

Query: 1166  IVNK-VVTPLSPPTNLHLEANPDTGVLTVSWERSTTPD---ITGY------------RIT 1209
              V K   +P SPP    +  +      TVSW    +     ITGY            R+ 
Sbjct: 17695 TVAKHKFSPPSPPGK-PVVTDITENAATVSWTLPKSDGGSPITGYYMERREVTGKWVRVN 17753

Query: 1210  TTP--------TNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISD 1261
              TP        T   +GN+ E  V A+       NL+   + + S   +K  +   PI  
Sbjct: 17754 KTPIADLKFRVTGLYEGNTYEFRVFAE-------NLAGLSKPSPSSDPIKACR---PIKP 17803

Query: 1262  TIIPEVPQLTDLSFVDITDSSIGLRWT-PLNS--STIIGYRITVVAAG--EGIPIFEDFV 1316
                P  P+L D S       +  L WT PL+   S I+GY +     G  +   I +D +
Sbjct: 17804 PGPPINPKLKDKS-----RETADLVWTKPLSDGGSPILGYVVECQKPGTAQWNRINKDEL 17858

Query: 1317  DSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAV-----PPPTDLRFTNIGP 1371
                  +  V GL  G +Y   +      GE  P  L +         PP  +L  T    
Sbjct: 17859 IRQCAF-RVPGLIEGNEYRFRIKAANIVGEGEPRELAESVIAKDILHPPEVELDVTCRDV 17917

Query: 1372  DTMRVTWA----------PPPSIDLTN---FLVRYSPVKNEEDV--AELSISPSDNAVVL 1416
              T+RV             P P I  T     LVR   V   +D+   EL I  +  A   
Sbjct: 17918 ITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRA--- 17974

Query: 1417  TNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSP---TGIDFSDITANSFTVHWIAPR 1473
                    +Y++S  +     + + +       LD P     +  +++T  + T+ W  P 
Sbjct: 17975 ----DHGKYIISAKNSSGHAQGSAI----VNVLDRPGPCQNLKVTNVTKENCTISWENPL 18026

Query: 1474  ----ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNG----- 1524
                 + IT + + +   +  G          R  +   NL    EY   + A N      
Sbjct: 18027 DNGGSEITNFIVEYRKPNQKGWSIVASDVTKR--LIKANLLANNEYYFRVCAENKVGVGP 18084

Query: 1525  --REESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYG---ETGGN 1579
                 ++P+L          P +L +     T + + W  P        ++Y       G+
Sbjct: 18085 TIETKTPILAINPIDRPGEPENLHIADKGKTFVYLKWRRPDYDGGSPNLSYHVERRLKGS 18144

Query: 1580  SPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASS--KPISINYRTEIDKPS 1637
                +       K T  +  +   V+  I  + V  + +   S   K   +  + ++ KP 
Sbjct: 18145 DDWERVHKGSIKETHYM--VDRCVENQIYEFRVQTKNEGGESDWVKTEEVVVKEDLQKP- 18201

Query: 1638  QMQVTDVQDNSIS-VKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMT------I 1690
                   V D  +S V  + +   +   R+    +  P P    T   D T++T      I
Sbjct: 18202 ------VLDLKLSGVLTVKAGDTI---RLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKI 18252

Query: 1691  EGLQPTVEYVVSVYAQNPSGE--------SQPLVQTAVTNI-DRP---KGLAFTDVDVDS 1738
             +    + ++ ++   ++  G+        +   V  A  N+ D+P   + L   DV  D 
Sbjct: 18253 DTRADSSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATVNVLDKPGPVRNLKIVDVSSDR 18312

Query: 1739  IKIAWESPQG----QVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSV- 1793
               + W+ P+     ++  Y +     +  +   + A      T   + L  G+EY   V 
Sbjct: 18313 CTVCWDPPEDDGGCEIQNYILEKCETKRMVWSTYSATVLTPGTTVTR-LIEGNEYIFRVR 18371

Query: 1794  ----VALHDDMESQPLIGTQSTAIPA-PTDLKFTQVTPTSLSAQWTPPNVQ----LTGYR 1844
                 +      ES+P+I       P  P   + T+V+   ++  W PP       +TGY 
Sbjct: 18372 AENKIGTGPPTESKPVIAKTKYDKPGRPDPPEVTKVSKEEMTVVWNPPEYDGGKSITGYF 18431

Query: 1845  VRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKD------TLTSRPAQGV 1898
             +    K  T  +     A     + V  L+   +Y+  V A  +      +L SRP    
Sbjct: 18432 LEKKEKHSTRWVPVNKSAIPERRMKVQNLLPDHEYQFRVKAENEIGIGEPSLPSRPVVAK 18491

Query: 1899  VTTLENVSPPRRARVTDATETTITISWRTKT----ETITGFQV-------DAVPANGQTP 1947
                +E   PP   RV D T+ +IT+ W          I G+ V       DA P  G   
Sbjct: 18492 -DPIEPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAPIIGYVVEMRPKIADASPDEGWKR 18550

Query: 1948  IQRTIKPDVRSYTITGLQPGTDYKIYLYTLN 1978
                  +   + +T+T L    +Y+  +   N
Sbjct: 18551 CNAAAQLVRKEFTVTSLDENQEYEFRVCAQN 18581



 Score = 74.3 bits (181), Expect = 1e-12
 Identities = 276/1411 (19%), Positives = 484/1411 (34%), Gaps = 227/1411 (16%)

Query: 814   PPDPTVD--QVDDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTL 867
             PP P  D   +D  +  + W  P     + IT Y +       G         T  S  +
Sbjct: 18994 PPQPPFDISDIDADACSLSWHIPLEDGGSNITNYIVEKCDVSRGDWVTALASVTKTSCRV 19053

Query: 868   SDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPS-PRDLQFVEVTDVKVTIM 926
               L PG +Y   + A      S P+   +     P    VPS P++ +  +V    + + 
Sbjct: 19054 GKLIPGQEYIFRVRAENRFGISEPLTSPKMVAQFPFG--VPSEPKNARVTKVNKDCIFVA 19111

Query: 927   WTPPES----AVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSH 982
             W  P+S     + GY ++    N          + R+T     GL  G+ Y F+++A++ 
Sbjct: 19112 WDRPDSDGGSPIIGYLIERKERNSLLWVKANDTLVRSTEYPCAGLVEGLEYSFRIYALNK 19171

Query: 983   GRESKPL--TAQQTTKL--DAPTNLQFVNETDSTVLVRWTPPR----AQITGYRLTVGLT 1034
                S P   T   T ++  D P   + ++ T STV + W  P+    ++I GY +     
Sbjct: 19172 AGSSPPSKPTEYVTARMPVDPPGKPEVIDVTKSTVSLIWARPKHDGGSKIIGYFVEACKL 19231

Query: 1035  RRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPY 1094
                +  + N  P        +  P  EYT + +  K   +          + P S     
Sbjct: 19232 PGDKWVRCNTAP--------HQIPQEEYTATGLEEKAQYQFRAIARTAVNISPPS----- 19278

Query: 1095  NTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQ 1154
               E ++   ++     PRI   + ++     +A   V  D+   V     P V +     
Sbjct: 19279 --EPSDPVTILAENVPPRIDLSVAMKSLLTVKAGTNVCLDA--TVFGKPMPTVSWKKDGT 19334

Query: 1155  VLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTN 1214
             +L+  +     +   + T       L      D+G  T++ E S+       ++      
Sbjct: 19335 LLKPAEGIKMAMQRNLCT-----LELFSVNRKDSGDYTITAENSSGSKSATIKLKVLDKP 19389

Query: 1215  GQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYT--VKDDKESVPISDTIIPEVPQLTD 1272
             G   +     +++D++  +++   P LE   S  T  + D +E      T  P   Q++ 
Sbjct: 19390 GPPASVKINKMYSDRAMLSWE---PPLEDGGSEITNYIVDKRE------TSRPNWAQVS- 19439

Query: 1273  LSFVDITDSSIGLRWTPLNSSTIIG--YRITVVAA---GEGIPIFEDFVDSSVGYYTVTG 1327
              + V IT  S+           I G  Y+  + A    G G P+F               
Sbjct: 19440 -ATVPITSCSV--------EKLIEGHEYQFRICAENKYGVGDPVFT-------------- 19476

Query: 1328  LEPGIDYDISVITLINGGESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAPPPS---I 1384
              EP I               A           PP     +NI  D M V+W PP      
Sbjct: 19477 -EPAI---------------AKNPYDPPGRCDPPV---ISNITKDHMTVSWKPPADDGGS 19517

Query: 1385  DLTNFLV--RYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLR 1442
              +T +L+  R +   N   V    I   +  +  T L  GTEY   V+++ +     P  
Sbjct: 19518 PITGYLLEKRETQAVNWTKVNRKPII--ERTLKATGLQEGTEYEFRVTAINKAGPGKPSD 19575

Query: 1443  GRQKTGLDSP-------TGIDFSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGR 1491
               +      P             D T +S ++ W  P     + I GY +          
Sbjct: 19576 ASKAAYARDPQYPPGPPAFPKVYDTTRSSVSLSWGKPAYDGGSPIIGYLVEVKRADSDNW 19635

Query: 1492  PREDRVPH-SRNSITLTNLTPGTEYVVSIVALNGREES-PLLIGQQSTVSDV--PRDLEV 1547
              R +   +  +    +T L   T+Y   + A+N    S P  +  +    D+  P + E+
Sbjct: 19636 VRCNLPQNLQKTRFEVTGLMEDTQYQFRVYAVNKIGYSDPSDVPDKHYPKDILIPPEGEL 19695

Query: 1548  VAATPTSLLISWDAPAVTVRYY---------RITYGETGGNSPVQEFTVPGSKSTATISG 1598
              A    +L++      VT+R Y         +IT+ +   N   +      S    T   
Sbjct: 19696 DADLRKTLILR---AGVTMRLYVPVKGRPPPKITWSKPNVNLRDRIGLDIKSTDFDTFLR 19752

Query: 1599  LKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLP--- 1655
              +    Y    Y +T           I +        P  + V ++  +S  V W P   
Sbjct: 19753 CENVNKYDAGKYILTLENSCGKKEYTIVVKVLDTPGPPVNVTVKEISKDSAYVTWEPPII 19812

Query: 1656  -SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQP 1714
                SP+  Y V            T T    +T   +  L+    Y   V+A+N  G   P
Sbjct: 19813 DGGSPIINYVVQKRDAERKS-WSTVTTECSKTSFRVANLEEGKSYFFRVFAENEYGIGDP 19871

Query: 1715  LVQTAVTNIDRPKG----LAFTDVDVDSIKIAWESPQG----QVSRYRVTYSSPEDGIHE 1766
                       +  G    L    V   S  I W+ P      ++  Y V + + E+    
Sbjct: 19872 GETRDAVKASQTPGPVVDLKVRSVSKSSCSIGWKKPHSDGGSRIIGYVVDFLTEENKWQR 19931

Query: 1767  LFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTP 1826
             +  +   +    +L     G EYT  V A +++ E  P        + A  D     V  
Sbjct: 19932 VMKSLSLQYSAKDLT---EGKEYTFRVSAENENGEGTP----SEITVVARDD-----VVA 19979

Query: 1827  TSLSAQWTPPNVQL----TGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVS 1882
               L  +  P    L    + +R+++  K K  P        D        L   T+  V 
Sbjct: 19980 PDLDLKGLPDLCYLAKENSNFRLKIPIKGKPAPSVSWKKGEDP-------LATDTRVSVE 20032

Query: 1883  VYALKDTLTSRPAQ----GVVT-TLENVSPPRRARVT-----------------DATETT 1920
               A+  TL     Q    G  T TL+NV+  +   ++                 + T   
Sbjct: 20033 SSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKEGTISIKVVGKPGIPTGPIKFDEVTAEA 20092

Query: 1921  ITISWRTKTET----ITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYL-- 1974
             +T+ W    +     IT + ++   +     +         ++ +T L  G +Y   +  
Sbjct: 20093 MTLKWAPPKDDGGSEITNYILEKRDSVNNKWVTCASAVQKTTFRVTRLHEGMEYTFRVSA 20152

Query: 1975  ---YTLNDNARSSPVVIDASTAI-DAPSNLRFLATTPNSLLVSWQPPR----ARITGYII 2026
                Y + +  +S P+V      + DAP     +    +S+ ++W  P+    + ITGY +
Sbjct: 20153 ENKYGVGEGLKSEPIVARHPFDVPDAPPPPNIVDVRHDSVSLTWTDPKKTGGSPITGYHL 20212

Query: 2027  KYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIAL------KNNQKSEPLI--- 2077
             ++++  S   +   +    + +  +TGL  G EY   V+A+      K +  SEP++   
Sbjct: 20213 EFKERNSLLWKRANKTPIRMRDFKVTGLTEGLEYEFRVMAINLAGVGKPSLPSEPVVALD 20272

Query: 2078  -----GRKKTV-----QKTPFVTHPGYDTGN 2098
                  G+ + +       T   T P YD G+
Sbjct: 20273 PIDPPGKPEVINITRNSVTLIWTEPKYDGGH 20303



 Score = 72.8 bits (177), Expect = 4e-12
 Identities = 334/1588 (21%), Positives = 550/1588 (34%), Gaps = 285/1588 (17%)

Query: 828   VVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAV 883
             ++ WS P+    + ITG+ I+     +  +    +    +   ++ L  G +Y   + A 
Sbjct: 15214 LLNWSDPEDDGGSEITGF-IIERKDAKMHTWRQPIETERSKCDITGLLEGQEYKFRVIAK 15272

Query: 884   EENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPES----AVTGYRV 939
              +     PV I       P      SP  L + E T   +T+ W  P S     + GY +
Sbjct: 15273 NKFGCGPPVEIGPILAVDPLGPPT-SPERLTYTERTKSTITLDWKEPRSNGGSPIQGYII 15331

Query: 940   DVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLD- 998
             +    + P        +   T   V  L     Y F+V AV+   ES+P         D 
Sbjct: 15332 EKRRHDKPDFERVNKRLCPTTSFLVENLDEHQMYEFRVKAVNEIGESEPSLPLNVVIQDD 15391

Query: 999   --APTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPR-QYNVGPSVSKYPLRN 1055
                PT    ++    T+ V+   P        +   +T    P+ +++   +V + P   
Sbjct: 15392 EVPPTIKLRLSVRGDTIKVKAGEP------VHIPADVTGLPMPKIEWSKNETVIEKPTDA 15445

Query: 1056  LQPASEYTVSLVAIKGNQESPKAT----GVFTTLQP---GSSI------------PPYNT 1096
             LQ   E  VS    K     PKA     G +T       GS              PP N 
Sbjct: 15446 LQITKE-EVSRSEAKTELSIPKAVREDKGTYTVTASNRLGSVFRNVHVEVYDRPSPPRNL 15504

Query: 1097  EVTET---TIVITW-TPAPRIGFKLGVRPSQGGEAPR------EVTSDSGS--IVVSGLT 1144
              VT+    +  +TW  P    G ++        +A R      EVT+ +      +  L 
Sbjct: 15505 AVTDIKAESCYLTWDAPLDNGGSEITHYVIDKRDASRKKAEWEEVTNTAVEKRYGIWKLI 15564

Query: 1145  PGVEYVYTIQVLR-----DGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSW---- 1195
             P  +Y + ++ +      D  + D  ++        PP    + A    G + VSW    
Sbjct: 15565 PNGQYEFRVRAVNKYGISDECKSDKVVIQDPYRLPGPPGKPKVLARTK-GSMLVSWTPPL 15623

Query: 1196  ERSTTPDITGYRITTTPTNGQQGNSLEE--VVHADQSSCTFD--NLSPGLEYNVSVYTVK 1251
             +   +P ITGY +          + +    +         F+   L  G++Y      + 
Sbjct: 15624 DNGGSP-ITGYWLEKREEGSPYWSRVSRAPITKVGLKGVEFNVPRLLEGVKYQFRAMAIN 15682

Query: 1252  --------DDKESVPISDTIIPEVPQLTDLSFVDITDSSIGLRWTPL---NSSTIIGYRI 1300
                     +  +     D I P  P        D T SSI L W P      S I GY +
Sbjct: 15683 AAGIGPPSEPSDPEVAGDPIFPPGPPSCP-EVKDKTKSSISLGWKPPAKDGGSPIKGYIV 15741

Query: 1301  TVVAAG--EGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAV 1358
              +   G  +   + E     +     V  L+    Y   V  +   GES P+  T +   
Sbjct: 15742 EMQEEGTTDWKRVNEPDKLITTCECVVPNLKELRKYRFRVKAVNEAGESEPSDTTGEI-- 15799

Query: 1359  PPPTDLR-----FTNIGPDTMRVTWA-------------PPPS----IDLTNFLVRYSPV 1396
              P TD++     F +IG     V  A             P P      D          V
Sbjct: 15800 -PATDIQEEPEVFIDIGAQDCLVCKAGSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGV 15858

Query: 1397  KNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTP-LRGRQKTGLDSPTGI 1455
              +  + A+L  + + + +++           S+++  +  + T   R +       P  +
Sbjct: 15859 HDIPEDAQLETAENSSVIIIPECKRSHTGKYSITAKNKAGQKTANCRVKVMDVPGPPKDL 15918

Query: 1456  DFSDITANSFTVHWIAPRAT----ITGYRIRHHPEHFSGRPREDRVPH-SRNSITLTNLT 1510
               SDIT  S  + W  P       I GY I        G+      P     +  + +L 
Sbjct: 15919 KVSDITRGSCRLSWKMPDDDGGDRIKGYVIEKRT--IDGKAWTKVNPDCGSTTFVVPDLL 15976

Query: 1511  PGTEYVVSIVALNGREESPLLIGQQSTVS-------DVPRDLEVVAATPTSLLISWDAPA 1563
                +Y   + A N     P +   Q T +       D P  L++   T  ++ +SW  P 
Sbjct: 15977 SEQQYFFRVRAENRFGIGPPVETIQRTTARDPIYPPDPPIKLKIGLITKNTVHLSWKPP- 16035

Query: 1564  VTVRYYRITYGETGGNSPVQEFTVP-------GSKSTA--------------TISGLKPG 1602
                        +  G SPV  + V        G+K  A              T+  L  G
Sbjct: 16036 -----------KNDGGSPVTHYIVECLAWDPTGTKKEAWRQCNKRDVEELQFTVEDLVEG 16084

Query: 1603  VDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTG 1662
              +Y   V AV   G S  S+             P   Q  D+   SI +K        T 
Sbjct: 16085 GEYEFRVKAVNAAGVSKPSATV----------GPCDCQRPDMPP-SIDLKEFMEVEEGTN 16133

Query: 1663  YRVTTTPKNGPGPT----KTKTAGPDQTEMTIEGLQPTVEYV----VSVYAQNPSGESQP 1714
               +    K  P PT    K     PD  E  +         V      V  Q+   ++  
Sbjct: 16134 VNIVAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDTGL 16193

Query: 1715  LVQTAVTNIDR---------------PKG-LAFTDVDVDSIKIAWESPQ----GQVSRYR 1754
                TAV N+                 P G + F  V  D + ++W  P+     +++ Y 
Sbjct: 16194 YTITAVNNLGTASKEMRLNVLGRPGPPVGPIKFESVSADQMTLSWFPPKDDGGSKITNYV 16253

Query: 1755  VTY--SSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVA-----LHDDMESQPLIG 1807
             +    ++ +  +H    + + +E T  +  L  G EY   ++A     + + ++S+P   
Sbjct: 16254 IEKREANRKTWVHV---SSEPKECTYTIPKLLEGHEYVFRIMAQNKYGIGEPLDSEPETA 16310

Query: 1808  TQSTAIP-APTDLKFTQVTPTSLSAQWTPPNVQ----LTGYRVRVTPKEKTGPM-KEINL 1861
                 ++P AP     + VT  S++  W  P       +TGY + +  K+ T    K +N 
Sbjct: 16311 RNLFSVPGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPVTGYWLEM--KDTTSKRWKRVNR 16368

Query: 1862  APDSS-----SVVVSGLMVATKYEVSVYALKD------TLTSRPAQGVVTTLENVSPPRR 1910
              P  +     S  V+GL+  + Y+  VYA+        +L S PA    T  + ++PP  
Sbjct: 16369 DPIKAMTLGVSYKVTGLIEGSDYQFRVYAINAAGVGPASLPSDPA----TARDPIAPPGP 16424

Query: 1911  A--RVTDATETTITISWRTKTET----ITGFQVDAVPANGQTPIQRTIKPDVRS--YTIT 1962
                +VTD T+++  + W    +     +TG+ V+     G+   ++    +VR     +T
Sbjct: 16425 PFPKVTDWTKSSADLEWSPPLKDGGSKVTGYIVE-YKEEGKEEWEKGKDKEVRGTKLVVT 16483

Query: 1963  GLQPGTDYKIYLYTLNDNARSSPV----VIDASTAIDAPSNLRFLATTPNSLLVSWQPPR 2018
             GL+ G  YK  +  +N      P     VI+    + +P +L+  A+  + ++V      
Sbjct: 16484 GLKEGAFYKFRVRAVNIAGIGEPGEVTDVIEMKDRLVSP-DLQLDASVRDRIVVH-AGGV 16541

Query: 2019  ARITGYIIKYEKPGSPPREVV--PRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPL 2076
              RI  Y+      G PP  V      R    EATI      T      + +KN Q+S   
Sbjct: 16542 IRIIAYV-----SGKPPPTVTWNMNERTLPQEATIE-----TTAISSSMVIKNCQRSHQG 16591

Query: 2077  I----------GRKKTV----------QKTPFVTHPGYDTGNGIQL----PGTSGQQPSV 2112
             +           RKKT+            TPF+ H    T    +L    P   G  P +
Sbjct: 16592 VYSLLAKNEAGERKKTIIVDVLDVPGPVGTPFLAHNL--TNESCKLTWFSPEDDGGSP-I 16648

Query: 2113  GQQMIFEEHGFRRTTPPTTATPIRHRPRPYPPNVGQ----EALSQTTISWAPFQDTSEYI 2168
                +I +    RR   P T T  R          G+       ++ +I   PF +TSE +
Sbjct: 16649 TNYVIEKRESDRRAWTPVTYTVTRQNATVQGLIQGKAYFFRIAAENSIGMGPFVETSEAL 16708

Query: 2169  ISCHPVGTDEEPLQFRVPG-TSTSATLT 2195
             +   P+   E P    V   T  + TLT
Sbjct: 16709 VIREPITVPERPEDLEVKEVTKNTVTLT 16736



 Score = 72.0 bits (175), Expect = 7e-12
 Identities = 342/1612 (21%), Positives = 545/1612 (33%), Gaps = 290/1612 (17%)

Query: 628   IQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISI 684
             + W +P+    S I+ Y++  R  +    W   T      + T++GL  G  Y  ++ + 
Sbjct: 16635 LTWFSPEDDGGSPITNYVIEKRESDRRA-WTPVTYTVTRQNATVQGLIQGKAYFFRIAAE 16693

Query: 685   QQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSAS 744
                G        F  TS +  +        T P  P       V E+T ++  ++W    
Sbjct: 16694 NSIGMGP-----FVETSEALVIREPI----TVPERP---EDLEVKEVTKNTVTLTWNPPK 16741

Query: 745   DTVSGFRVEYELSEE--GDEPQYLDLPSTATS--VNIPDLLPGRKYIVNVYQISEDGEQS 800
                    + Y L     G E  +        S    +  L  G  Y   V  ++  G+  
Sbjct: 16742 YDGGSEIINYVLESRLIGTEKFHKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGK 16801

Query: 801   LILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPE 860
                 T   T  D    PT+       + +R     A    Y     P V     E ++ E
Sbjct: 16802 PSFCTKPITCKDELAPPTLHLDFRDKLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLE 16861

Query: 861   TANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQET---TGTPRSDTVPSPRD----L 913
               +  T     P       I A   +     VV++  T    G  + + V  P      +
Sbjct: 16862 --DDRTHIKTTPATLALEKIKAKRSDSGKYCVVVENSTGSRKGFCQVNVVDRPGPPVGPV 16919

Query: 914   QFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPGEHGQRLPI---SRNTFAEVTG 966
              F EVT   + I W PP     S +T Y ++   V         +P+   S  T  +V+ 
Sbjct: 16920 SFDEVTKDYMVISWKPPLDDGGSKITNYIIEKKEVG----KDVWMPVTSASAKTTCKVSK 16975

Query: 967   LSPGVTYYFKVFAVSHGRESKPLTAQQTTKLD------APTNLQFVNETDSTVLVRWTPP 1020
             L  G  Y F++ A +    S PL +      D      AP        T  + LV W  P
Sbjct: 16976 LLEGKDYIFRIHAENLYGISDPLVSDSMKAKDRFRVPDAPDQPIVTEVTKDSALVTWNKP 17035

Query: 1021  R---AQITGYRLTVGLTRRGQPRQYNVGP--SVSKYPLRNLQPASEYTVSLVA---IKGN 1072
                   IT Y L    T   +  +    P    +K+ + +L    +Y   + A   I   
Sbjct: 17036 HDGGKPITNYILEKRETMSKRWARVTKDPIHPYTKFRVPDLLEGCQYEFRVSAENEIGIG 17095

Query: 1073  QESPKATGVFTTLQPGSSIPPYNTEVTETT---IVITWTPAPRIGFKLGVRPSQGGEAPR 1129
               SP +  VF         PP N E  +TT   + +TW P                  PR
Sbjct: 17096 DPSPPSKPVFAKDPIAKPSPPVNPEAIDTTCNSVDLTWQP------------------PR 17137

Query: 1130  EVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTG 1189
                 D GS ++        Y+   Q + D + R A              N   E+ P+T 
Sbjct: 17138 H---DGGSKILG-------YIVEYQKVGDEEWRRA--------------NHTPESCPETK 17173

Query: 1190  VLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPG---LEYNVS 1246
                       T     +R+      G+      +  H  +     D L P    L+ N++
Sbjct: 17174 YKVTGLRDGQTYK---FRVLAVNAAGES-----DPAHVPEPVLVKDRLEPPELILDANMA 17225

Query: 1247  VYTVKDDKESVPISDT-----IIPEVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGYRIT 1301
                    ++ + + DT     II  VP      F  +T       W   +       RI 
Sbjct: 17226 ------REQHIKVGDTLRLSAIIKGVP------FPKVT-------WKKEDRDAPTKARID 17266

Query: 1302  VVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAVPPP 1361
             V   G  + I  +      G Y++T   P     +SV  L+                 PP
Sbjct: 17267 VTPVGSKLEI-RNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDKPG------------PP 17313

Query: 1362  TDLRFTNIGPDTMRVTWAPPPSID---LTNFLVRYSPVKNEEDVAELSISPSDNAVVLTN 1418
              DL  + I  D+  +TW  P       +TN++V    V + +  + LS +    +    +
Sbjct: 17314 RDLEVSEIRKDSCYLTWKEPLDDGGSVITNYVVERRDVASAQ-WSPLSATSKKKSHFAKH 17372

Query: 1419  LLPGTEYVVSVSSVYEQHESTPLRGRQKT--GLDS------PTGIDFSDITANSFTVHWI 1470
             L  G +Y+  V++   Q+   P     K    LD       P  +   D+     ++ W 
Sbjct: 17373 LNEGNQYLFRVAAE-NQYGRGPFVETPKPIKALDPLHPPGPPKDLHHVDVDKTEVSLVWN 17431

Query: 1471  APR----ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN--- 1523
              P     + ITGY + +  E      +   V +      +T L  G  Y   + A N   
Sbjct: 17432 KPDRDGGSPITGYLVEYQEEGTQDWIKFKTVTNLE--CVVTGLQQGKTYRFRVKAENIVG 17489

Query: 1524  -GREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPV 1582
              G  ++ + I  Q  +  VP  +E+       L++       TVR+  I  G      P 
Sbjct: 17490 LGLPDTTIPIECQEKL--VPPSVELDVKLIEGLVVK---AGTTVRFPAIIRGVP---VPT 17541

Query: 1583  QEFTVPGSK---------------STATISGL--KPGVDYTITVYAVTGRGDSPASSKPI 1625
              ++T  GS+               S  TI     +   +Y ITV        + A SK +
Sbjct: 17542 AKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEYQITV-------SNAAGSKTV 17594

Query: 1626  SINYRTEIDKPSQ----MQVTDVQDNSISVKWLP----SSSPVTGYRVTT--TPKNGPGP 1675
             +++  T +D P      + + DV    +++ W P      SPV  Y V    T K+  G 
Sbjct: 17595 AVHL-TVLDVPGPPTGPINILDVTPEHMTISWQPPKDDGGSPVINYIVEKQDTRKDTWGV 17653

Query: 1676  TKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDR------PKGL 1729
                 ++G  +T++ I  LQ   EYV  V A+N  G   PL  T      +      P   
Sbjct: 17654 V---SSGSSKTKLKIPHLQKGCEYVFRVRAENKIGVGPPLDSTPTVAKHKFSPPSPPGKP 17710

Query: 1730  AFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQ----GLRP 1785
               TD+  ++  ++W  P+         Y      +   +   + +   A+L+    GL  
Sbjct: 17711 VVTDITENAATVSWTLPKSDGGSPITGYYMERREVTGKWVRVN-KTPIADLKFRVTGLYE 17769

Query: 1786  GSEYTVSVVALH------DDMESQPLIGTQSTAIPA-PTDLKFTQVTPTSLSAQWTPP-- 1836
             G+ Y   V A +          S P+   +    P  P + K    +  +    WT P  
Sbjct: 17770 GNTYEFRVFAENLAGLSKPSPSSDPIKACRPIKPPGPPINPKLKDKSRETADLVWTKPLS 17829

Query: 1837  --NVQLTGYRVRVTPKEKTGPMKEINLAP--DSSSVVVSGLMVATKYEVSVYALKDTLTS 1892
                  + GY V    K  T     IN        +  V GL+   +Y   + A       
Sbjct: 17830 DGGSPILGYVVE-CQKPGTAQWNRINKDELIRQCAFRVPGLIEGNEYRFRIKAANIVGEG 17888

Query: 1893  RP---AQGVVTTLENVSPPR-------RARVTDATETTITISWRTK-------TETITG- 1934
              P   A+ V+   + + PP        R  +T     TI I  R K       T T  G 
Sbjct: 17889 EPRELAESVIAK-DILHPPEVELDVTCRDVITVRVGQTIRILARVKGRPEPDITWTKEGK 17947

Query: 1935  -----FQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVID 1989
                   +VD +    +  +Q  IK  VR+           Y I     + +A+ S +V  
Sbjct: 17948 VLVREKRVDLIQDLPRVELQ--IKEAVRA-------DHGKYIISAKNSSGHAQGSAIV-- 17996

Query: 1990  ASTAIDAP---SNLRFLATTPNSLLVSWQPP----RARITGYIIKYEKPGSPPREVVPRP 2042
                 +D P    NL+    T  +  +SW+ P     + IT +I++Y KP      +V   
Sbjct: 17997 --NVLDRPGPCQNLKVTNVTKENCTISWENPLDNGGSEITNFIVEYRKPNQKGWSIV--- 18051

Query: 2043  RPGVTEATI-TGLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQKTPFVTHPG 2093
                VT+  I   L    EY   V A +N     P I  K  +     +  PG
Sbjct: 18052 ASDVTKRLIKANLLANNEYYFRVCA-ENKVGVGPTIETKTPILAINPIDRPG 18102



 Score = 64.3 bits (155), Expect = 1e-09
 Identities = 115/519 (22%), Positives = 183/519 (35%), Gaps = 81/519 (15%)

Query: 1633  IDKPS---QMQVTDVQDNSISVKWLPSSSP----VTGYRVTTTP-KNGPGPTKTKTAGPD 1684
             +DKP     +++ DV  +  +V W P        +  Y +     K     T + T    
Sbjct: 18294 LDKPGPVRNLKIVDVSSDRCTVCWDPPEDDGGCEIQNYILEKCETKRMVWSTYSATVLTP 18353

Query: 1685  QTEMT--IEGLQPTVEYVVSVYAQN-----PSGESQPLV-QTAVTNIDRPKGLAFTDVDV 1736
              T +T  IEG     EY+  V A+N     P  ES+P++ +T      RP     T V  
Sbjct: 18354 GTTVTRLIEGN----EYIFRVRAENKIGTGPPTESKPVIAKTKYDKPGRPDPPEVTKVSK 18409

Query: 1737  DSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGE----EDTAELQGLRPGSEYTVS 1792
             + + + W  P+    +    Y   +   H     P  +    E   ++Q L P  EY   
Sbjct: 18410 EEMTVVWNPPEYDGGKSITGYFLEKKEKHSTRWVPVNKSAIPERRMKVQNLLPDHEYQFR 18469

Query: 1793  VVALHD------DMESQPLIGTQSTAIPAP-TDLKFTQVTPTSLSAQWTPP----NVQLT 1841
             V A ++       + S+P++       P P T+ +    T  S++  W  P       + 
Sbjct: 18470 VKAENEIGIGEPSLPSRPVVAKDPIEPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAPII 18529

Query: 1842  GYRVRVTPKEKTGP----MKEINLAPD--SSSVVVSGLMVATKYEVSVYALKDTLTSRPA 1895
             GY V + PK          K  N A         V+ L    +YE  V A       RPA
Sbjct: 18530 GYVVEMRPKIADASPDEGWKRCNAAAQLVRKEFTVTSLDENQEYEFRVCAQNQVGIGRPA 18589

Query: 1896  Q--GVVTTLENVSPPRRARVTDATETTIT-------------------ISWRTK--TETI 1932
             +    +   E + PP         +  I                    ++WR       +
Sbjct: 18590 ELKEAIKPKEILEPPEIDLDASMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVV 18649

Query: 1933  TGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDAST 1992
                QVD V       I  + + D   Y++T + P  +  +++     N R    V+D   
Sbjct: 18650 RKGQVDLVDTMAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFV-----NVR----VLDTPG 18700

Query: 1993  AIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREVVPRPRPGVTE 2048
              +   S+L+    T  S  VSW PP     +++T YI++  +        V  P    T 
Sbjct: 18701 PV---SDLKVSDVTKTSCHVSWAPPENDGGSQVTHYIVEKREADRKTWSTVT-PEVKKTS 18756

Query: 2049  ATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQKTP 2087
               +T L PG EY   V A+       P    K  +   P
Sbjct: 18757 FHVTNLVPGNEYYFRVTAVNEYGPGVPTDVPKPVLASDP 18795



 Score = 61.6 bits (148), Expect = 9e-09
 Identities = 181/841 (21%), Positives = 296/841 (35%), Gaps = 156/841 (18%)

Query: 1360  PPTDLRFTNIGPDTMRVTWAPPPS---IDLTNFLVRYSPVKNEEDVAELSISPSDNAVVL 1416
             P  +L  T      + + W  P +     +  ++V    +K +  V     + S    V 
Sbjct: 13092 PVRNLEVTETFDGEVSLAWEEPLTDGGSKIIGYVVERRDIKRKTWVLATDRAESCEFTVT 13151

Query: 1417  TNLLPGTEYVVSVSS-----VYEQHES-TPLRGRQKTGLDSPT-GIDFSDITANSFTVHW 1469
                  G EY+  VS+       E  E+  P+  R K  +  P   +  +D+     ++ W
Sbjct: 13152 GLQKGGVEYLFRVSARNRVGTGEPVETDNPVEARSKYDVPGPPLNVTITDVNRFGVSLTW 13211

Query: 1470  IAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGR 1525
               P     A IT Y I    +          V     S T+T++  G EY   +     R
Sbjct: 13212 EPPEYDGGAEITNYVIELRDKTSIRWDTAMTVRAEDLSATVTDVVEGQEYSFRV-----R 13266

Query: 1526  EESPLLIGQQSTVSDV------------PRDLEVVAATPTSLLISWDAP----AVTVRYY 1569
              ++ + +G+ S  +              P +L     T +S+ + W+ P       +  Y
Sbjct: 13267 AQNRIGVGKPSAATPFVKVADPIERPSPPVNLTSSDQTQSSVQLKWEPPLKDGGSPILGY 13326

Query: 1570  RITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINY 1629
              I   E G ++ ++       + T  ++GL+ G  Y   V A    G S  S     +  
Sbjct: 13327 IIERCEEGKDNWIRCNMKLVPELTYKVTGLEKGNKYLYRVSAENKAGVSDPSEILGPLTA 13386

Query: 1630  RTEIDKPSQMQVTDVQDNSISVKWLPSSS--PVTGYRVTTTPKNGPGPTKTKTAGPDQTE 1687
                  +P+ M ++  +D    +   P +   P TGY         P PT T   G    E
Sbjct: 13387 DDAFVEPT-MDLSAFKDGLEVIVPNPITILVPSTGY---------PRPTATWCFGDKVLE 13436

Query: 1688  ----MTIEGLQPTVEYVVSVYAQNPSG----ESQPLVQTAVTNID--------RPKGLAF 1731
                 + ++ L    E V+S   ++  G    + +  V+T    ID         PK L F
Sbjct: 13437 TGDRVKMKTLSAYAELVISPSERSDKGIYTLKLENRVKTISGEIDVNVIARPSAPKELKF 13496

Query: 1732  TDVDVDSIKIAWESPQ----GQVSRY--------RVTYSSPEDGIHEL-FPAPDGEEDTA 1778
              D+  DS+ + WE P       ++ Y        R T++   D + +L F  PD      
Sbjct: 13497 GDITKDSVHLTWEPPDDDGGSPLTGYVVEKREVSRKTWTKVMDFVTDLEFTVPD------ 13550

Query: 1779  ELQGLRPGSEYTVSVVALHDDMESQPL-------IGTQSTAIPAPTDLKFTQVTPTSLSA 1831
                 L  G EY   V A +     +P        + T +T    P ++K+   T  S+  
Sbjct: 13551 ----LVQGKEYLFKVCARNKCGPGEPAYVDEPVNMSTPATVPDPPENVKWRDRTANSIFL 13606

Query: 1832  QWTPP----NVQLTGYRVRVTPKEKTGPMKEINLAPD--SSSVVVSGLMVATKYEVSVYA 1885
              W PP      ++ GY V   P+   G  K +        + + V+GL     Y   V A
Sbjct: 13607 TWDPPKNDGGSRIKGYIVERCPR---GSDKWVACGEPVAETKMEVTGLEEGKWYAYRVKA 13663

Query: 1886  LKDTLTSRPAQGVVTTLENVSPPRRARVTDATETT-----------ITISWRTKTE---T 1931
             L     S+P++          P    +  D  E             +T+   TK E   T
Sbjct: 13664 LNRQGASKPSR----------PTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPAT 13713

Query: 1932  ITGFQVDAVPANGQTPIQRTIKPDVR----------SYTITGLQPGTDYKIYLYTLNDNA 1981
             +TG      P    T     +K D R          + TI   +        +  +N   
Sbjct: 13714 VTG---KPEPKITWTKADMILKQDKRITIENVPKKSTVTIVDSKRSDTGTYIIEAVNVCG 13770

Query: 1982  RSSPVV-IDASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPR 2036
             R++ VV ++       P+       T  S L++W PPR    ++IT Y+++     S   
Sbjct: 13771 RATAVVEVNVLDKPGPPAAFDITDVTNESCLLTWNPPRDDGGSKITNYVVERRATDS--- 13827

Query: 2037  EVVPRPRPGV--TEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQKTPFVTHPGY 2094
             EV  +    V  T    T L P  EY   V A       E + G  + VQ +P      +
Sbjct: 13828 EVWHKLSSTVKDTNFKATKLIPNKEYIFRVAA-------ENMYGVGEPVQASPITAKYQF 13880

Query: 2095  D 2095
             D
Sbjct: 13881 D 13881



 Score = 58.2 bits (139), Expect = 1e-07
 Identities = 314/1663 (18%), Positives = 573/1663 (34%), Gaps = 254/1663 (15%)

Query: 611   PVEVFITETPSQP-----------NSHPIQWNAPQPS---HISKYILRWRPKNSVGRWKE 656
             P+ V     PS+P           +S  + W+ P+ +    I+ Y +  R + S   WK 
Sbjct: 27648 PITVITLGPPSKPKGPIRFDEIKADSVILSWDVPEDNGGGEITCYSIEKR-ETSQTNWKM 27706

Query: 657   ATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETT 716
                     ++ +  L     Y+ ++ +  +YG              S P+ S+ +  +  
Sbjct: 27707 VCSSVARTTFKVPNLVKDAEYQFRVRAENRYG-------------VSQPLVSSIIVAKHQ 27753

Query: 717   PFSPLVATSESVTEITASSFVVSW----VSASDTVSGFRVEYELSEEGDEPQYLDLPSTA 772
                P       +  +T+    ++W          V+GF VE +        +    P + 
Sbjct: 27754 FRIPGPPGKPVIYNVTSDGMSLTWDAPVYDGGSEVTGFHVEKKERNSILWQKVNTSPISG 27813

Query: 773   TSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDP--TVDQVDDT--SIV 828
                    L+ G  Y   VY  +  G  S     S+ T   +P DP  T D +D T  +I 
Sbjct: 27814 REYRATGLVEGLDYQFRVYAENSAGLSSPS-DPSKFTLAVSPVDPPGTPDYIDVTRETIT 27872

Query: 829   VRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETAN-SVTLSDLQPGVQYNITIYA- 882
             ++W+ P     + I GY I      E      N  + +    T++ L PG +Y   I A 
Sbjct: 27873 LKWNPPLRDGGSKIVGYSIEKRQGNE-RWVRCNFTDVSECQYTVTGLSPGDRYEFRIIAR 27931

Query: 883   -----VEENQESTPVVIQQETTGTPRSDTVPSPRD---LQFVEVTDVKVTIMWTPPESAV 934
                  +    +S+ +++ ++    P  +  P   D   ++  E   +K  +   P    V
Sbjct: 27932 NAVGTISPPSQSSGIIMTRDENVPPIVEFGPEYFDGLIIKSGESLRIKALVQGRPVPR-V 27990

Query: 935   TGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFK--------VFAVSHGRES 986
             T ++  V              I +    E+T +    + + +        V+ V     S
Sbjct: 27991 TWFKDGV-------------EIEKRMNMEITDVLGSTSLFVRDATRDHRGVYTVEAKNAS 28037

Query: 987   KPLTAQQTTKL-DAPTN----LQFVNETDSTVLVRWTPPR----AQITGYRLTVGLTRRG 1037
                 A+   K+ D P      ++F N T   + + W  P     A IT Y +    T R 
Sbjct: 28038 GSAKAEIKVKVQDTPGKVVGPIRFTNITGEKMTLWWDAPLNDGCAPITHYIIEKRETSRL 28097

Query: 1038  QPRQYNVGPSVSKYPLRNLQPASEYTVSLVAI------KGNQESPKATGVFTTLQPGSSI 1091
                          Y    L   +EY   + A+      +     P    +  T+     I
Sbjct: 28098 AWALIEDKCEAQSYTAIKLINGNEYQFRVSAVNKFGVGRPLDSDPVVAQIQYTVPDAPGI 28157

Query: 1092  PPYNTEVTETTIVITWTPAPRIG------FKLGVRPSQGGEAPREVTSDSGS---IVVSG 1142
             P   + +T  +I +TW      G      + L  R  +     + ++    S     V+G
Sbjct: 28158 PE-PSNITGNSITLTWARPESDGGSEIQQYILERREKKSTRWVKVISKRPISETRFKVTG 28216

Query: 1143  LTPGVEYVYTIQVLRDGQERDAPIVNKVVT---PLSPPTNLHLEANPDTGVLTVSWERST 1199
             LT G EY + +          A  +++++    P++PP    +    DT   TVS E S 
Sbjct: 28217 LTEGNEYEFHVMAENAAGVGPASGISRLIKCREPVNPPGPPTVVKVTDTSKTTVSLEWSK 28276

Query: 1200  TP-----DITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKD-- 1252
                    +I GY I     +    + +       ++  T  +L  G EY   V  +    
Sbjct: 28277 PVFDGGMEIIGYIIEMCKADLGDWHKVNAEACV-KTRYTVTDLQAGEEYKFRVSAINGAG 28335

Query: 1253  DKESVPISDTI-------IPEVPQLTDLSFVDITDSSIGLR--------------WTPLN 1291
               +S  ++ TI        PE+    +     +  +   +R              W+  +
Sbjct: 28336 KGDSCEVTGTIKAVDRLTAPELDIDANFKQTHVVRAGASIRLFIAYQGRPTPTAVWSKPD 28395

Query: 1292  SSTIIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTT 1351
             S+  +   I    +   + + E+   +  G YT+T            +   +G +S   T
Sbjct: 28396 SNLSLRADIHTTDSFSTLTV-ENCNRNDAGKYTLT------------VENNSGSKSITFT 28442

Query: 1352  LTQQTAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAE---LSIS 1408
             +       PP  + F ++   +  + W   P +D    +  Y   K E        +S  
Sbjct: 28443 VKVLDTPGPPGPITFKDVTRGSATLMW-DAPLLDGGARIHHYVVEKREASRRSWQVISEK 28501

Query: 1409  PSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDS----PTGIDFSDITANS 1464
              +     + +L  G  Y   VS+V E     P    +          P  +D  D + +S
Sbjct: 28502 CTRQIFKVNDLAEGVPYYFRVSAVNEYGVGEPYEMPEPIVATEQPAPPRRLDVVDTSKSS 28561

Query: 1465  FTVHWIAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRN-SITLTNLTPGTEYVVSI 1519
               + W+ P     + ITGY +    +   G        H++  + T+  L   TEY   +
Sbjct: 28562 AVLAWLKPDHDGGSRITGYLLEMRQK---GSDFWVEAGHTKQLTFTVERLVEKTEYEFRV 28618

Query: 1520  VALNGREESPLLIGQQSTVSDVPR-----DLEVV--------AATPTSL---LISWDAPA 1563
              A N    S       S +   P+     DL  +        A +P ++   +    AP 
Sbjct: 28619 KAKNDAGYSEPREAFSSVIIKEPQIEPTADLTGITNQLITCKAGSPFTIDVPISGRPAPK 28678

Query: 1564  VTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVD--YTITVYAVTGRGDSPAS 1621
             VT +   +   ET   S     T    ++T T+     G    Y +T+       ++ A 
Sbjct: 28679 VTWKLEEMRLKETDRVS----ITTTKDRTTLTVKDSMRGDSGRYFLTL-------ENTAG 28727

Query: 1622  SKPISINYRTEIDKPSQM----QVTDVQDNSISVKWLP----SSSPVTGYRVTTTPKNGP 1673
              K  S+     I +P  +    +V+ V   S  + W        + +T Y +    ++G 
Sbjct: 28728 VKTFSVTV-VVIGRPGPVTGPIEVSSVSAESCVLSWGEPKDGGGTEITNY-IVEKRESGT 28785

Query: 1674  GPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAV------TNIDRPK 1727
                +   +   +T++ +  L   +EY   V ++N  G S+PL    +           P 
Sbjct: 28786 TAWQLVNSSVKRTQIKVTHLTKYMEYSFRVSSENRFGVSKPLESAPIIAEHPFVPPSAPT 28845

Query: 1728  GLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGE----EDTAELQGL 1783
                   V  +++ I WE P        + Y   +   + +    + +    E   ++ GL
Sbjct: 28846 RPEVYHVSANAMSIRWEEPYHDGGSKIIGYWVEKKERNTILWVKENKVPCLECNYKVTGL 28905

Query: 1784  RPGSEYTVSVVALH------DDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPP- 1836
               G EY     AL+          S+P++      + AP   + T VT +++S  W+ P 
Sbjct: 28906 VEGLEYQFRTYALNAAGVSKASEASRPIMA--QNPVDAPGRPEVTDVTRSTVSLIWSAPA 28963

Query: 1837  ---NVQLTGYRVRVTPKEKTGP---MKEINLAPDSSSVVVSGLMVATKYEVSVYALKDT- 1889
                  ++ GY +   P  + G    +K        +   V+ L     YE  V A     
Sbjct: 28964 YDGGSKVVGYIIERKPVSEVGDGRWLKCNYTIVSDNFFTVTALSEGDTYEFRVLAKNAAG 29023

Query: 1890  LTSRPAQ--GVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVP------ 1941
             + S+ ++  G VT  +  +PP+     DA      ++ R  ++ +    V   P      
Sbjct: 29024 VISKGSESTGPVTCRDEYAPPKAE--LDARLHGDLVTIRAGSDLVLDAAVGGKPEPKIIW 29081

Query: 1942  ANGQTPIQRTIKPDV-----RSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDA 1996
               G   +    K  +     R+  +      +D   Y  T+  NA  +  V      +D+
Sbjct: 29082 TKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSGKYTLTVK-NASGTKAVSVMVKVLDS 29140

Query: 1997  P---SNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREVVPRPRPGVTEA 2049
             P     L     T     ++W  P+    A IT YI++  +       +V    P ++  
Sbjct: 29141 PGPCGKLTVSRVTQEKCTLAWSLPQEDGGAEITHYIVERRETSRLNWVIVEGECPTLS-Y 29199

Query: 2050  TITGLEPGTEYTIYVIALKN-----NQKSEPLIGRKKTVQKTP 2087
              +T L    EY   V A+         +SEP++ R      +P
Sbjct: 29200 VVTRLIKNNEYIFRVRAVNKYGPGVPVESEPIVARNSFTIPSP 29242



 Score = 55.5 bits (132), Expect = 6e-07
 Identities = 128/535 (23%), Positives = 202/535 (37%), Gaps = 90/535 (16%)

Query: 593   GIGEWHCQPLQTYPSSSGPVEVFITETPSQP-------NSHPIQWNAPQ---PSHISKYI 642
             GIGE    PL + P ++  +   +   P +P       NS  + W  P+    S ++ Y 
Sbjct: 16298 GIGE----PLDSEPETARNL-FSVPGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPVTGYW 16352

Query: 643   LRWRPKNSVGRWK-------EATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRF 695
             L  +   S  RWK       +A   G   SY + GL  G  Y+ ++ +I   G    +  
Sbjct: 16353 LEMKDTTSK-RWKRVNRDPIKAMTLGV--SYKVTGLIEGSDYQFRVYAINAAGVGPASL- 16408

Query: 696   DFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWV----SASDTVSGFR 751
                    S P T+        P +P       VT+ T SS  + W          V+G+ 
Sbjct: 16409 ------PSDPATARD------PIAPPGPPFPKVTDWTKSSADLEWSPPLKDGGSKVTGYI 16456

Query: 752   VEYELSEEGDEP--QYLDLPSTATSVNIPDLLPGRKY-----IVNVYQISEDGEQSLILS 804
             VEY+  EEG E   +  D     T + +  L  G  Y      VN+  I E GE + ++ 
Sbjct: 16457 VEYK--EEGKEEWEKGKDKEVRGTKLVVTGLKEGAFYKFRVRAVNIAGIGEPGEVTDVIE 16514

Query: 805   TSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETA-- 862
                       PD  +D      IVV        I        P+V  +  E  LP+ A  
Sbjct: 16515 MKDRLVS---PDLQLDASVRDRIVVHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEATI 16571

Query: 863   ------NSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFV 916
                   +S+ + + Q   Q   ++ A  E  E    +I            VP P    F+
Sbjct: 16572 ETTAISSSMVIKNCQRSHQGVYSLLAKNEAGERKKTIIVDVLD-------VPGPVGTPFL 16624

Query: 917   --EVTDVKVTIMWTPPE----SAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPG 970
                +T+    + W  PE    S +T Y ++    +          ++R   A V GL  G
Sbjct: 16625 AHNLTNESCKLTWFSPEDDGGSPITNYVIEKRESDRRAWTPVTYTVTRQN-ATVQGLIQG 16683

Query: 971   VTYYFKVFA---VSHG---RESKPLTAQQT-TKLDAPTNLQFVNETDSTVLVRWTPPR-- 1021
               Y+F++ A   +  G     S+ L  ++  T  + P +L+    T +TV + W PP+  
Sbjct: 16684 KAYFFRIAAENSIGMGPFVETSEALVIREPITVPERPEDLEVKEVTKNTVTLTWNPPKYD 16743

Query: 1022  --AQITGYRLTVGLTRRGQPRQYNVGPSVS-KYPLRNLQPAS--EYTVSLVAIKG 1071
               ++I  Y L   L    +  +      +S KY ++ L+     EY VS V I G
Sbjct: 16744 GGSEIINYVLESRLIGTEKFHKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVG 16798



 Score = 52.8 bits (125), Expect = 4e-06
 Identities = 80/336 (23%), Positives = 120/336 (35%), Gaps = 46/336 (13%)

Query: 602   LQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQP---SHISKYILRWRPKN-SVGRWKEA 657
             ++ Y   S P  + +T+  ++  S  + W+AP     S I+ Y++  R  +     W+E 
Sbjct: 15492 VEVYDRPSPPRNLAVTDIKAE--SCYLTWDAPLDNGGSEITHYVIDKRDASRKKAEWEEV 15549

Query: 658   TIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTP 717
             T       Y I  L P   YE ++ ++ +YG  +  + D         V  +       P
Sbjct: 15550 TNTAVEKRYGIWKLIPNGQYEFRVRAVNKYGISDECKSD-------KVVIQDPYRLPGPP 15602

Query: 718   FSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTA----- 772
               P V         T  S +VSW    D        Y L +  +   Y    S A     
Sbjct: 15603 GKPKVLAR------TKGSMLVSWTPPLDNGGSPITGYWLEKREEGSPYWSRVSRAPITKV 15656

Query: 773   ----TSVNIPDLLPGRKY-----IVNVYQISEDGEQSLILSTSQTTAPDAPPD-PTVDQV 822
                    N+P LL G KY      +N   I    E S          P  PP  P V   
Sbjct: 15657 GLKGVEFNVPRLLEGVKYQFRAMAINAAGIGPPSEPSDPEVAGDPIFPPGPPSCPEVKDK 15716

Query: 823   DDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPE---TANSVTLSDLQPGVQ 875
               +SI + W  P     +PI GY +            +N P+   T     + +L+   +
Sbjct: 15717 TKSSISLGWKPPAKDGGSPIKGYIVEMQEEGTTDWKRVNEPDKLITTCECVVPNLKELRK 15776

Query: 876   YNITIYAVEENQESTPVVIQQETTG-TPRSDTVPSP 910
             Y   + AV E  ES P     +TTG  P +D    P
Sbjct: 15777 YRFRVKAVNEAGESEP----SDTTGEIPATDIQEEP 15808



 Score = 48.5 bits (114), Expect = 8e-05
 Identities = 107/537 (19%), Positives = 187/537 (34%), Gaps = 65/537 (12%)

Query: 610   GPVEVFITETPSQPNSHPIQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSY 666
             GPV        ++ + H + W  P+    S ++ YI+  R  +    W   T      S+
Sbjct: 18700 GPVSDLKVSDVTKTSCH-VSWAPPENDGGSQVTHYIVEKREADRK-TWSTVTPEVKKTSF 18757

Query: 667   TIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSE 726
              +  L PG  Y  ++ ++ +YG           T    PV ++    E  P   L     
Sbjct: 18758 HVTNLVPGNEYYFRVTAVNEYG-------PGVPTDVPKPVLASDPLSEPDPPRKL----- 18805

Query: 727   SVTEITASSFVVSWV----SASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLP 782
              VTE+T +S  ++W+         + G+   Y   E+  +           S+ +  L  
Sbjct: 18806 EVTEMTKNSATLAWLPPLRDGGAKIDGYITSYREEEQPADRWTEYSVVKDLSLVVTGLKE 18865

Query: 783   GRKY-----IVNVYQISEDGEQSLILSTSQTTAPD---APPDPTVDQVDDTSIVVRWSRP 834
             G+KY       N   +S   E   +    +   P     P   T+       I       
Sbjct: 18866 GKKYKFRVAARNAVGVSLPREAEGVYEAKEQLLPPKILMPEQITIKAGKKLRIEAHVYGK 18925

Query: 835   QAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDL--QPGVQYNITIYAVEENQESTPV 892
               P   ++      V  S   ++  ++++ + + D+  +    Y++T             
Sbjct: 18926 PHPTCKWKKGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIK 18985

Query: 893   VIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPG 948
             V+  +  G P+      P D+  ++      ++ W  P     S +T Y V+   V+  G
Sbjct: 18986 VVVMDAPGPPQ-----PPFDISDIDAD--ACSLSWHIPLEDGGSNITNYIVEKCDVS-RG 19037

Query: 949   EHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKL------DAPTN 1002
             +    L     T   V  L PG  Y F+V A +    S+PLT+ +            P N
Sbjct: 19038 DWVTALASVTKTSCRVGKLIPGQEYIFRVRAENRFGISEPLTSPKMVAQFPFGVPSEPKN 19097

Query: 1003  LQFVNETDSTVLVRWTPPRAQ----ITGYRLTVGLTRRGQPRQYNVGPSV---SKYPLRN 1055
              +        + V W  P +     I GY   +    R          ++   ++YP   
Sbjct: 19098 ARVTKVNKDCIFVAWDRPDSDGGSPIIGY--LIERKERNSLLWVKANDTLVRSTEYPCAG 19155

Query: 1056  LQPASEYTVSLVAIKGNQESP--KATGVFTTLQPGSSIPPYNTE---VTETTIVITW 1107
             L    EY+  + A+     SP  K T   T   P    PP   E   VT++T+ + W
Sbjct: 19156 LVEGLEYSFRIYALNKAGSSPPSKPTEYVTARMPVD--PPGKPEVIDVTKSTVSLIW 19210



 Score = 43.9 bits (102), Expect = 0.002
 Identities = 50/204 (24%), Positives = 83/204 (40%), Gaps = 22/204 (10%)

Query: 717   PFSPLVATSESVTEITASSFVVSWVSASDT----VSGFRVEYELSEEGDEPQYLDLPSTA 772
             P  P+V     +  +  +S V+SW   +D     ++ + VE   ++EG E Q +    + 
Sbjct: 30726 PTGPIV-----IEALLKNSAVISWKPPADDGGSWITNYVVEKCEAKEGAEWQLVSSAISV 30780

Query: 773   TSVNIPDLLPGRKYIV-----NVYQISEDGE-QSLILSTSQTTAPDAPPDPTVDQVDDTS 826
             T+  I +L     Y       N + IS+  E  S+++  S    P AP  PT+  V   S
Sbjct: 30781 TTCRIVNLTENAGYYFRVSAQNTFGISDPLEVSSVVIIKSPFEKPGAPGKPTITAVTKDS 30840

Query: 827   IVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSV-TLSDLQPGVQYNITIY 881
              VV W  P     A I  Y +      +     +   E   +V ++ +L  G++Y   + 
Sbjct: 30841 CVVAWKPPASDGGAKIRNYYLEKREKKQNKWISVTTEEIRETVFSVKNLIEGLEYEFRVK 30900

Query: 882   AVEENQESTPVVIQQETTGTPRSD 905
                   ES    I +    TP+SD
Sbjct: 30901 CENLGGESEWSEISEPI--TPKSD 30922



 Score = 41.2 bits (95), Expect = 0.013
 Identities = 92/413 (22%), Positives = 157/413 (38%), Gaps = 51/413 (12%)

Query: 1376  VTWAPPPSID---LTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSV 1432
             ++W PP       +TN++V     K   +   +S + S     + NL     Y   VS+ 
Sbjct: 30742 ISWKPPADDGGSWITNYVVEKCEAKEGAEWQLVSSAISVTTCRIVNLTENAGYYFRVSAQ 30801

Query: 1433  YEQHESTPLRGRQKTGLDSPTGID-------FSDITANSFTVHWIAPRATITGYRIRHHP 1485
                  S PL       + SP            + +T +S  V W  P A+  G +IR++ 
Sbjct: 30802 NTFGISDPLEVSSVVIIKSPFEKPGAPGKPTITAVTKDSCVVAW-KPPASDGGAKIRNYY 30860

Query: 1486  EHFSGRPREDRVPHSRNSITLT-----NLTPGTEYVVSIVA--LNGREESPLLIGQQSTV 1538
                  + +   +  +   I  T     NL  G EY   +    L G  E   +    +  
Sbjct: 30861 LEKREKKQNKWISVTTEEIRETVFSVKNLIEGLEYEFRVKCENLGGESEWSEISEPITPK 30920

Query: 1539  SDVP----------RDLEVVAATPTSLLISWDA-PAVTVRYYRITYGET----GGNSPVQ 1583
             SDVP          R+L V   +  +L+      P   V++YR   G+     G    +Q
Sbjct: 30921 SDVPIQAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYR--QGKEIIADGLKYRIQ 30978

Query: 1584  EFTVPGSKSTATISGLKPGVDYTITVYAV--TGRGDSPASSKPISINYRTEIDKPSQMQ- 1640
             EF   G      I+ +    D   TVY V  T +G S + +  + +    +I  P  ++ 
Sbjct: 30979 EFK--GGYHQLIIASV---TDDDATVYQVRATNQGGSVSGTASLEVEVPAKIHLPKTLEG 31033

Query: 1641  ---VTDVQDNSISVKWLPSSS---PVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQ 1694
                V  ++   +S+K +P S    PV  ++      +  G  +        + +   G++
Sbjct: 31034 MGAVHALRGEVVSIK-IPFSGKPDPVITWQKGQDLIDNNGHYQVIVTRSFTSLVFPNGVE 31092

Query: 1695  PTVEYVVSVYAQNPSGESQPLVQTAVTNI-DRPKGLAFTDVDVDSIKIAWESP 1746
                     V A+N  G  Q  V+  V ++ D P+G+  +DV  DS+ + W  P
Sbjct: 31093 RKDAGFYVVCAKNRFGIDQKTVELDVADVPDPPRGVKVSDVSRDSVNLTWTEP 31145



 Score = 37.7 bits (86), Expect = 0.14
 Identities = 36/131 (27%), Positives = 53/131 (40%), Gaps = 8/131 (6%)

Query: 894   IQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPVNLPGE 949
             I Q+T     +D    PR ++  +V+   V + WT P     S +T Y V+        E
Sbjct: 31109 IDQKTVELDVADVPDPPRGVKVSDVSRDSVNLTWTEPASDGGSKITNYIVEKCATT--AE 31166

Query: 950   HGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQ--TTKLDAPTNLQFVN 1007
                R+  +R T   V  L    +Y F+V A +    SKP    +   TK D    + +  
Sbjct: 31167 RWLRVGQARETRYTVINLFGKTSYQFRVIAENKFGLSKPSEPSEPTITKEDKTRAMNYDE 31226

Query: 1008  ETDSTVLVRWT 1018
             E D T  V  T
Sbjct: 31227 EVDETREVSMT 31237



 Score = 35.0 bits (79), Expect = 0.90
 Identities = 38/169 (22%), Positives = 71/169 (42%), Gaps = 17/169 (10%)

Query: 1610  YAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWL-PSS---SPVTGYRV 1665
             Y V  +       K + ++     D P  ++V+DV  +S+++ W  P+S   S +T Y V
Sbjct: 31099 YVVCAKNRFGIDQKTVELDVADVPDPPRGVKVSDVSRDSVNLTWTEPASDGGSKITNYIV 31158

Query: 1666  TTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPL--VQTAVTNI 1723
                        +   A   +T  T+  L     Y   V A+N  G S+P    +  +T  
Sbjct: 31159 EKCATTAERWLRVGQA--RETRYTVINLFGKTSYQFRVIAENKFGLSKPSEPSEPTITKE 31216

Query: 1724  DRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPD 1772
             D+ + + + D +VD  +        +VS  + ++SS ++   +   A D
Sbjct: 31217 DKTRAMNY-DEEVDETR--------EVSMTKASHSSTKELYEKYMIAED 31256


>gi|110349717 titin isoform novex-2 [Homo sapiens]
          Length = 27118

 Score =  175 bits (444), Expect = 4e-43
 Identities = 382/1656 (23%), Positives = 623/1656 (37%), Gaps = 244/1656 (14%)

Query: 630   WNAPQPSHISK---YILRWRPKNSVG--RWKEA--TIPGHLNSYTIKGLKPGVVYEGQLI 682
             W+AP     SK   YI+  +P + VG  RW +   TI    N +T+  L  G  YE +++
Sbjct: 22654 WSAPAYDGGSKVVGYIIERKPVSEVGDGRWLKCNYTIVSD-NFFTVTALSEGDTYEFRVL 22712

Query: 683   SIQQYGHQEVTRFDFTTTSTST-PVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWV 741
             +    G         +  S ST PVT                  + VT    S  V+   
Sbjct: 22713 AKNAAGV-------ISKGSESTGPVTCRDEYAPPKAELDARLHGDLVTIRAGSDLVL--- 22762

Query: 742   SASDTVSGFRVEYELS-EEGDEP---------QYLDLPSTATSVNIPDLLPGRKYIVNVY 791
                D   G + E ++   +GD+          QY    +TA  +   D     KY + V 
Sbjct: 22763 ---DAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAV-IKFCDRSDSGKYTLTVK 22818

Query: 792   QISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ----APITGYRIVYSP 847
               S  G +++ +      +P      TV +V      + WS PQ    A IT Y +    
Sbjct: 22819 NAS--GTKAVSVMVKVLDSPGPCGKLTVSRVTQEKCTLAWSLPQEDGGAEITHYIVERRE 22876

Query: 848   S-------VEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG 900
             +       VEG    L       S  ++ L    +Y   + AV +     PV  + E   
Sbjct: 22877 TSRLNWVIVEGECPTL-------SYVVTRLIKNNEYIFRVRAVNKYGPGVPV--ESEPIV 22927

Query: 901   TPRSDTVPSPRDL-QFVEVTDVKVTIMWTPPES----AVTGYRVDVIPV-NLPGEHGQRL 954
                S T+PSP  + + V      + I WT PES     ++ Y VD     +L      + 
Sbjct: 22928 ARNSFTIPSPPGIPEEVGTGKEHIIIQWTKPESDGGNEISNYLVDKREKKSLRWTRVNKD 22987

Query: 955   PISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNL-------QFVN 1007
              +  +T  +VT L  G  Y F+V AV+    S+P  A        P+         + V+
Sbjct: 22988 YVVYDTRLKVTSLMEGCDYQFRVTAVNAAGNSEPSEASNFISCREPSYTPGPPSAPRVVD 23047

Query: 1008  ETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSV--SKYPLRNLQPASE 1061
              T  ++ + WT P       I GY L +      Q  + +   ++  +++ + +L+   +
Sbjct: 23048 TTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDTDQWYRVHTNATIRNTEFTVPDLKMGQK 23107

Query: 1062  YT--VSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGV 1119
             Y+  V+ V +KG  E  ++      ++P   I   + E+ +    +  T   R G  L +
Sbjct: 23108 YSFRVAAVNVKGMSEYSES---IAEIEPVERIEIPDLELADD---LKKTVTIRAGASLRL 23161

Query: 1120  RPSQGGEAPREVT-----SDSGSIVVSGLTPGVEYV------------YTIQVLRDGQER 1162
               S  G  P  +T      D  S  +   T     +            YTI+      ++
Sbjct: 23162 MVSVSGRPPPVITWSKQGIDLASRAIIDTTESYSLLIVDKVNRYDAGKYTIEAENQSGKK 23221

Query: 1163  DAPIVNKVV-TPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSL 1221
              A ++ KV  TP   P+    E + D+  +T++WE    P I G      P N       
Sbjct: 23222 SATVLVKVYDTPGPCPSVKVKEVSRDS--VTITWE---IPTIDG----GAPVNNYIVEKR 23272

Query: 1222  EEVVHA-----DQSSCTFDNLSPGLEYNVSVYTVKDDK-----ESVPISDTI-IPEVPQL 1270
             E  + A      + S T   +S  +E  +  + V  +      E    SD + + EVP +
Sbjct: 23273 EAAMRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYGIGEPCETSDAVLVSEVPLV 23332

Query: 1271  -TDLSFVDITDSSIGLRW-TPL--NSSTIIGYRITVVAAGEGIPIFEDFVDSSVGYYTVT 1326
                L  VD+T S++ L W  PL    S + GY +    AG    +    +  +V  +TVT
Sbjct: 23333 PAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGTERWMKVVTLKPTVLEHTVT 23392

Query: 1327  GLEPGIDYDISVITLINGGESAP----TTLT-QQTAVPPPTDLRFTNIGPDTMRV----- 1376
              L  G  Y   +      G S P    T +T Q   V P  DL  + +   T+ V     
Sbjct: 23393 SLNEGEQYLFRIRAQNEKGVSEPRETVTAVTVQDLRVLPTIDL--STMPQKTIHVPAGRP 23450

Query: 1377  -------TWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSV 1429
                       PPP+     F       ++E    E     +   +  T +    EY + +
Sbjct: 23451 VELVIPIAGRPPPAASW--FFAGSKLRESERVTVETHTKVAKLTIRETTIRDTGEYTLEL 23508

Query: 1430  SSVY-EQHESTPLRGRQKTGLDSPTG-IDFSDITANSFTVHWIAPR----ATITGYRIRH 1483
              +V     E+  +    K G   PTG I   +I A S T+ W  P     A ++GY +  
Sbjct: 23509 KNVTGTTSETIKVIILDKPG--PPTGPIKIDEIDATSITISWEPPELDGGAPLSGYVVEQ 23566

Query: 1484  HPEHFSG-RPREDRVPHSRNSITLTNLTPGTEYVVSIVALN----GREESPLLIGQQST- 1537
                H  G  P  + V  +R++   T LT G EYV  + A N    G      +I  +S+ 
Sbjct: 23567 RDAHRPGWLPVSESV--TRSTFKFTRLTEGNEYVFRVAATNRFGIGSYLQSEVIECRSSI 23624

Query: 1538  -VSDVPRDLEVVAATPTSLLISWDAP----AVTVRYYRITYGETGGNSPVQEFTVPGSKS 1592
              +   P  L++   +   + ++W  P       V  Y +   E   +  V+   VP + +
Sbjct: 23625 RIPGPPETLQIFDVSRDGMTLTWYPPEDDGGSQVTGYIVERKEVRADRWVRVNKVPVTMT 23684

Query: 1593  TATISGLKPGVDYTITVYAVTGRGDSPAS--SKPI-SINYRTEIDKPSQMQVTDVQDNSI 1649
                 +GL  G++Y   V A+  RG    S  SKPI +++      KP   +VTD    S+
Sbjct: 23685 RYRSTGLTEGLEYEHRVTAINARGSGKPSRPSKPIVAMDPIAPPGKPQNPRVTDTTRTSV 23744

Query: 1650  SVKWL----PSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYA 1705
             S+ W        S VTGY +     +    TK  T      E T+  L    EY   V A
Sbjct: 23745 SLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTKCNTTPTKIREYTLTHLPQGAEYRFRVLA 23804

Query: 1706  QNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDS-IKIAWESPQGQVSRYRVTYSSPEDGI 1764
              N  G  +P        +   + L + D ++D   +      QG V R  +        I
Sbjct: 23805 CNAGGPGEPAEVPGTVKV--TEMLEYPDYELDERYQEGIFVRQGGVIRLTIPIKGKPFPI 23862

Query: 1765  HELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMES------------QPLIGTQSTA 1812
              +     +G +D ++   +     +T  V+   D  +S            +  +  +   
Sbjct: 23863 CKW--TKEG-QDISKRAMIATSETHTELVIKEADRGDSGTYDLVLENKCGKKAVYIKVRV 23919

Query: 1813  IPAPTD----LKFTQVTPTSLSAQWTPP----NVQLTGYRV--RVTPKEKTGPMKEINLA 1862
             I +P      L++  +   S+   W PP       + GY +  R  PK        I+  
Sbjct: 23920 IGSPNSPEGPLEYDDIQVRSVRVSWRPPADDGGADILGYILERREVPK---AAWYTIDSR 23976

Query: 1863  PDSSSVVVSGLMVATKYEVSVYALKDTLTSRP--AQGVVTTLENVSPP----RRARVTDA 1916
                +S+VV GL    +Y   V A      S+P  ++  VT    ++PP        V D 
Sbjct: 23977 VRGTSLVVKGLKENVEYHFRVSAENQFGISKPLKSEEPVTPKTPLNPPEPPSNPPEVLDV 24036

Query: 1917  TETTITISW-RTKTE---TITGFQVDAVPANGQTPIQRT-IKPDVRSYTITGLQPGTDYK 1971
             T++++++SW R K +    +TG+ ++    +    ++    +     YT+TGL P  +Y+
Sbjct: 24037 TKSSVSLSWSRPKDDGGSRVTGYYIERKETSTDKWVRHNKTQITTTMYTVTGLVPDAEYQ 24096

Query: 1972  IYLYTLND------NARSSPVVI-DASTAIDAPSNLRFLATTPNSLLVSWQPPRA----R 2020
               +   ND      +  S PVV  D       P  L  L+ + +S+ + W+ P       
Sbjct: 24097 FRIIAQNDVGLSETSPASEPVVCKDPFDKPSQPGELEILSISKDSVTLQWEKPECDGGKE 24156

Query: 2021  ITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRK 2080
             I GY ++Y + G    +   + R    + TI GL   TEY   V A      S P     
Sbjct: 24157 ILGYWVEYRQSGDSAWKKSNKERIKDKQFTIGGLLEATEYEFRVFAENETGLSRP----- 24211

Query: 2081  KTVQKTPFVTHPGYDTGNGIQLPGTSGQQPSVGQQM 2116
                            T   I+   TSG+ P + ++M
Sbjct: 24212 -------------RRTAMSIKTKLTSGEAPGIRKEM 24234



 Score =  157 bits (398), Expect = 9e-38
 Identities = 342/1617 (21%), Positives = 590/1617 (36%), Gaps = 235/1617 (14%)

Query: 624   NSHPIQWNAPQP---SHISKYILRWRPKNSVGRWKEAT-IPGHLNSYTIKGLKPGVVYEG 679
             N+  + W  P     S I+ Y +  R K S+ RW  A   P       + GL+ G  YE 
Sbjct: 14281 NTATVSWKRPVDDGGSEITGYHVERREKKSL-RWVRAIKTPVSDLRCKVTGLQEGSTYEF 14339

Query: 680   QLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVS 739
             ++ +  + G    +              S++V  +   + P   ++  VT+ T  S  ++
Sbjct: 14340 RVSAENRAGIGPPSE------------ASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLA 14387

Query: 740   W----VSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVN---IPDLLPGRKYIVNVYQ 792
             W          ++G+ VE++  + GDE    D   TA  +    +PDL    KY   +  
Sbjct: 14388 WGKPHYDGGLEITGYVVEHQ--KVGDEAWIKDTTGTALRITQFVVPDLQTKEKYNFRISA 14445

Query: 793   ISEDGE-QSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWS---RPQAPITGYRIVYSPS 848
             I++ G  +  ++   +    +  PD  +D     ++VVR     R   PI G     +P 
Sbjct: 14446 INDAGVGEPAVIPDVEIVEREMAPDFELDAELRRTLVVRAGLSIRIFVPIKGRP---APE 14502

Query: 849   VEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTV- 907
             V  +   +NL   AN      ++    + + I       ++   V+  E     +S  V 
Sbjct: 14503 VTWTKDNINLKNRAN------IENTESFTLLIIPECNRYDTGKFVMTIENPAGKKSGFVN 14556

Query: 908   ------PSP-RDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPGEHGQRLPI 956
                   P P  +L+  ++T   VT+ W  P     S +T Y V+                
Sbjct: 14557 VRVLDTPGPVLNLRPTDITKDSVTLHWDLPLIDGGSRITNYIVEKREATRKSYSTATTKC 14616

Query: 957   SRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDA----PTNLQFVNETDST 1012
              + T+ +VTGLS G  Y+F+V A +     +P    +  K       P +L  ++ T ST
Sbjct: 14617 HKCTY-KVTGLSEGCEYFFRVMAENEYGIGEPTETTEPVKASEAPSPPDSLNIMDITKST 14675

Query: 1013  VLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSVS-KYPLRNLQPASEYTVSLV 1067
             V + W  P+    ++ITGY   +   R+G  +  ++      +  +RNL    EYT  ++
Sbjct: 14676 VSLAWPKPKHDGGSKITGY--VIEAQRKGSDQWTHITTVKGLECVVRNLTEGEEYTFQVM 14733

Query: 1068  AIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWT-------------PAPRIG 1114
             A+     S         ++  + +P  +       +VI                P P + 
Sbjct: 14734 AVNSAGRSAPRESRPVIVKEQTMLPELDLRGIYQKLVIAKAGDNIKVEIPVLGRPKPTVT 14793

Query: 1115  FKLGVRP-SQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTP 1173
             +K G +   Q      E T+ S  + ++         Y +       E    I  +V   
Sbjct: 14794 WKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLTARNIVGEVGDVITIQVHDI 14853

Query: 1174  LSPPTNLHLEANPDTGVLTVSW---ERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQS 1230
               PPT         +  +T SW   E      I+ Y +    T+      L   V     
Sbjct: 14854 PGPPTGPIKFDEVSSDFVTFSWDPPENDGGVPISNYVVEMRQTDSTTWVELATTVIRTTY 14913

Query: 1231  SCTFDNLSPGLEYNVSVYTVKDDKESVPISDTII-----------PEVPQLTDLSFVDIT 1279
               T   L+ GLEY   V           I+   I           P  PQ+T      +T
Sbjct: 14914 KAT--RLTTGLEYQFRVKAQNRYGVGPGITSACIVANYPFKVPGPPGTPQVTA-----VT 14966

Query: 1280  DSSIGLRW-TPLNS--STIIGYRITVVAAGEGIPIFEDFVDSSV---GYYTVTGLEPGID 1333
               S+ + W  PL+   S I+GY    V   E   I    V  ++     +  +GL  GI 
Sbjct: 14967 KDSMTISWHEPLSDGGSPILGYH---VERKERNGILWQTVSKALVPGNIFKSSGLTDGIA 15023

Query: 1334  YDISVITLINGGESAPTTLTQQTA----VPPPTDLRFTNIGPDTMRVTWAPPP---SIDL 1386
             Y+  VI     G+S P+  ++       + PP      NI   T+ + WA P       +
Sbjct: 15024 YEFRVIAENMAGKSKPSKPSEPMLALDPIDPPGKPVPLNITRHTVTLKWAKPEYTGGFKI 15083

Query: 1387  TNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQ- 1445
             T+++V    + N   +     +  +N   ++ L     Y   V +       +P      
Sbjct: 15084 TSYIVEKRDLPNGRWLKANFSNILENEFTVSGLTEDAAYEFRVIAKNAAGAISPPSEPSD 15143

Query: 1446  ----KTGLDSP---TGIDFSDIT----ANSF------------TVHWIAPRATITGY-RI 1481
                 +  +++P     + F D        +F            T+ W      + G  ++
Sbjct: 15144 AITCRDDVEAPKIKVDVKFKDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKL 15203

Query: 1482  RHHPEHFSGR-PREDRVPHSRNSITLTNLTPG--TEYVVSIVALN--GREESPLLIGQQS 1536
                   FS     +D       + TLT   PG   +++ ++  L+  G  E PL + +  
Sbjct: 15204 EIKIADFSTNLVNKDSTRRDSGAYTLTATNPGGFAKHIFNVKVLDRPGPPEGPLAVTE-- 15261

Query: 1537  TVSDVPRDLEVVAATPTSLLISWDAP----AVTVRYYRITYGETGGNSPVQEFTVPGSKS 1592
                           T    ++SW  P       + +Y +   ET   +    +T   S+ 
Sbjct: 15262 -------------VTSEKCVLSWFPPLDDGGAKIDHYIVQKRETSRLA----WTNVASEV 15304

Query: 1593  TAT---ISGLKPGVDYTITVYAVTGRG-DSPASSKPI-SINYRTEIDKPSQMQVTDVQDN 1647
               T   ++ L  G +Y   V AV   G   P  S+P+ ++N     D P   +VT +  +
Sbjct: 15305 QVTKLKVTKLLKGNEYIFRVMAVNKYGVGEPLESEPVLAVNPYGPPDPPKNPEVTTITKD 15364

Query: 1648  SISVKW----LPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSV 1703
             S+ V W        S +  Y V    K G    K            + GL    EY   +
Sbjct: 15365 SMVVCWGHPDSDGGSEIINYIVERRDKAGQRWIKCNKKTLTDLRYKVSGLTEGHEYEFRI 15424

Query: 1704  YAQNPSGESQPLVQT-------AVTNIDRPKGLAFTDVDVDSIKIAWESP----QGQVSR 1752
              A+N +G S P   +        V     P      D    SI IAW  P      +++ 
Sbjct: 15425 MAENAAGISAPSPTSPFYKACDTVFKPGPPGNPRVLDTSRSSISIAWNKPIYDGGSEITG 15484

Query: 1753  YRVTYSSPEDGIHELFPAPDGEEDTA-ELQGLRPGSEYTVSVVALHDDMESQPLI--GT- 1808
             Y V  + PE+   ++   P G + T+  + GL    EY + + A++ +   +P +  GT 
Sbjct: 15485 YMVEIALPEEDEWQIVTPPAGLKATSYTITGLTENQEYKIRIYAMNSEGLGEPALVPGTP 15544

Query: 1809  --QSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSS 1866
               +   +P   +L        ++ A  T          +R+    K  P  E+  A D  
Sbjct: 15545 KAEDRMLPPEIELDADLRKVVTIRACCT----------LRLFVPIKGRPAPEVKWARDHG 15594

Query: 1867  SVVVSGLMVAT------------KYEVSVYAL--KDTLTSRPAQGVVTTLENVSPPRRAR 1912
               +    + +T            +++   Y L  +++  S+ A   V  L+   PP+  +
Sbjct: 15595 ESLDKASIESTSSYTLLIVGNVNRFDSGKYILTVENSSGSKSAFVNVRVLDTPGPPQDLK 15654

Query: 1913  VTDATETTITISWRTKT----ETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGT 1968
             V + T+T++T++W          I  + V+   +  +            S+ +  LQ G 
Sbjct: 15655 VKEVTKTSVTLTWDPPLLDGGSKIKNYIVEKRESTRKAYSTVATNCHKTSWKVDQLQEGC 15714

Query: 1969  DYKIYLYTLNDNARSSPVVIDASTAIDA------PSNLRFLATTPNSLLVSWQPPR---- 2018
              Y  Y   L +N     +  + + ++ A      P  +  +  T NS+ +SW+ P     
Sbjct: 15715 SY--YFRVLAENEYGIGLPAETAESVKASERPLPPGKITLMDVTRNSVSLSWEKPEHDGG 15772

Query: 2019  ARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEP 2075
             +RI GYI++ +  GS         +  VTEATITGL  G EY+  V A      S+P
Sbjct: 15773 SRILGYIVEMQTKGSDKWATCATVK--VTEATITGLIQGEEYSFRVSAQNEKGISDP 15827



 Score =  146 bits (368), Expect = 3e-34
 Identities = 363/1662 (21%), Positives = 600/1662 (36%), Gaps = 237/1662 (14%)

Query: 612  VEVFITETPSQPNSHPIQ----------WNAPQP---SHISKYILRWRPKNSVGRWKEAT 658
            VEV + + P  P +  I           WN P+    S I+ Y++  R  +S   W + +
Sbjct: 7471 VEVNVLDKPGPPAAFDITDVTNESCLLTWNPPRDDGGSKITNYVVERRATDSEV-WHKLS 7529

Query: 659  IPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPF 718
                  ++    L P   Y  ++ +   YG  E             PV ++ +T +    
Sbjct: 7530 STVKDTNFKATKLIPNKEYIFRVAAENMYGVGE-------------PVQASPITAKYQFD 7576

Query: 719  SPLVATSESVTEITASSFVVSWVSASDT----VSGFRVEYELSEEGDEPQYLDLPSTATS 774
             P   T    ++IT  +  ++W    D     ++G+ VE    +     +   +P   T+
Sbjct: 7577 PPGPPTRLEPSDITKDAVTLTWCEPDDDGGSPITGYWVERLDPDTDKWVRCNKMPVKDTT 7636

Query: 775  VNIPDLLPGRKYIVNVY--QISEDGEQSL----ILSTSQTTAPDAPPDPTVDQVDDTSIV 828
              +  L   +KY   V    ++  G+ S     IL       P  P  PTV  V  TS+ 
Sbjct: 7637 YRVKGLTNKKKYRFRVLAENLAGPGKPSKSTEPILIKDPIDPPWPPGKPTVKDVGKTSVR 7696

Query: 829  VRWSRPQ----APITGY--RIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYA 882
            + W++P+    A I  Y   ++ + + E       +P T +   L  L  G +Y+  + A
Sbjct: 7697 LNWTKPEHDGGAKIESYVIEMLKTGTDEWVRVAEGVPTTQH--LLPGLMEGQEYSFRVRA 7754

Query: 883  VEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYR 938
            V +  ES P           +      PR L+ + +T     + WT PE    S +T Y 
Sbjct: 7755 VNKAGESEPSEPSDPVLCREKLYPPSPPRWLEVINITKNTADLKWTVPEKDGGSPITNYI 7814

Query: 939  VDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSH-GR------ESKPLTA 991
            V+   V   G       + ++T   VT L+ G  Y F+V A +  G+      E   L  
Sbjct: 7815 VEKRDVRRKGWQTVDTTV-KDTKCTVTPLTEGSLYVFRVAAENAIGQSDYTEIEDSVLAK 7873

Query: 992  QQTTKLDAPTNLQFVNETDSTVLVRWTPPR--AQITGYRLTVGLTRRGQPRQYNVGPSVS 1049
               T    P  L  V+ T   V ++W PP+        R  +    R   R    G +  
Sbjct: 7874 DTFTTPGPPYALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKERLGTRWVKAGKTAG 7933

Query: 1050 KYPLRNLQPASEYTVSLVAIKGNQES-----PKATGVFTTLQPGS-SIPPYNTEVTET-- 1101
                  +    E T     ++   E+      + T + +   P S   PP +  VT+   
Sbjct: 7934 PDCNFRVTDVIEGTEVQFQVRAENEAGVGHPSEPTEILSIEDPTSPPSPPLDLHVTDAGR 7993

Query: 1102 -TIVITWTP------APRIGFKLGVRPSQGGEAPREVTS----DSGSIVVSGLTPGVEYV 1150
              I I W P      +P IG+ + + P  G E    V S    D    V  G+ P  EYV
Sbjct: 7994 KHIAIAWKPPEKNGGSPIIGYHVEMCP-VGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYV 8052

Query: 1151 YTIQVLRD-GQERDAPIVNKVVT--PLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYR 1207
              ++ +   G    + I   VV   P   PT + LE +    ++ +  E+ + P    +R
Sbjct: 8053 LRVRAVNAIGVSEPSEISENVVAKDPDCKPT-IDLETH---DIIVIEGEKLSIP--VPFR 8106

Query: 1208 ITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEY------NVSVYTV----KDDKESV 1257
                PT     +  +EV  +D+ +   D++S  LE       +  +YT+    K    + 
Sbjct: 8107 AVPVPTVSWHKDG-KEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATA 8165

Query: 1258 PISDTIIPEVPQLTDLSFVDITDSSIGLRWTPL---NSSTIIGYRITVVAAGEG--IPIF 1312
             I+  +I       D+   DIT SS  L W P      + I+ Y +    AG    IP+ 
Sbjct: 8166 SINVKVIGLPGPCKDIKASDITKSSCKLTWEPPEFDGGTPILHYVLERREAGRRTYIPVM 8225

Query: 1313 EDFVDSSVGYYTVTGLEPGIDY--DISVITLINGGESAP---TTLTQQTAVP--PPTDLR 1365
                  S   +TV  L P  +Y   +  +  + GGE        + Q    P  PP D+ 
Sbjct: 8226 SGENKLS---WTVKDLIPNGEYFFRVKAVNKVGGGEYIELKNPVIAQDPKQPPDPPVDVE 8282

Query: 1366 FTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLT----NLLP 1421
              N   + M +TW  PP  D  + ++ Y   K  +              +LT     L  
Sbjct: 8283 VHNPTAEAMTITW-KPPLYDGGSKIMGYIIEKIAKGEERWKRCNEHLVPILTYTAKGLEE 8341

Query: 1422 GTEYVVSVSSVYEQHESTPLRGRQKT----GLDSP---------------TGIDFSDITA 1462
            G EY   V +      S P R    T     +D+P                 +D S   +
Sbjct: 8342 GKEYQFRVRAENAAGISEPSRATPPTKAVDPIDAPKVILRTSLEVKRGDEIALDASISGS 8401

Query: 1463 NSFTVHWIAPRATITGYRIRHHPEHFSGRPR------EDRVPHSRNSITLTNLTPGTE-- 1514
               T+ WI     I    I+        R +      E  V      +++ N   G    
Sbjct: 8402 PYPTITWIKDENVIVPEEIKKRAAPLVRRRKGEVQEEEPFVLPLTQRLSIDNSKKGESQL 8461

Query: 1515 ------------YVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAP 1562
                        Y++ +   +G  ++P  +    T    P +        TS+L  W+ P
Sbjct: 8462 RVRDSLRPDHGLYMIKVENDHGIAKAPCTVSVLDTPGP-PINFVFEDIRKTSVLCKWEPP 8520

Query: 1563 -----AVTVRYYRITYGETGGNSPVQEFTVPGS---KSTATISGLKPGVDYTITVYAVTG 1614
                 +  + Y   T  +     P  E+ V  S       +++ L  G +Y   V A   
Sbjct: 8521 LDDGGSEIINY---TLEKKDKTKPDSEWIVVTSTLRHCKYSVTKLIEGKEYLFRVRAENR 8577

Query: 1615 RGDS-PASSKP-ISINYRTEIDKPSQMQVTDVQDNSISVKW---LPSSSPVTGYRVTTTP 1669
             G   P  SKP ++ +     D P +  V DV  NS+ VKW     + SP+ GY +    
Sbjct: 8578 FGPGPPCVSKPLVAKDPFGPPDAPDKPIVEDVTSNSMLVKWNEPKDNGSPILGYWLEKRE 8637

Query: 1670 KNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSG------ESQPLVQTAVTNI 1723
             N    ++   +  +  +  ++GL   + YV  V A+N +G       S P       + 
Sbjct: 8638 VNSTHWSRVNKSLLNALKANVDGLLEGLTYVFRVCAENAAGPGKFSPPSDPKTAHDPISP 8697

Query: 1724 DRPKGLAFTDVDVDSIKIAWESPQ----GQVSRYRVTYSSPEDGIHELFPAPDGEEDTAE 1779
              P     TD    +I++ WE P     G++  Y V       G +E     +      +
Sbjct: 8698 PGPPIPRVTDTSSTTIELEWEPPAFNGGGEIVGYFV--DKQLVGTNEWSRCTEKMIKVRQ 8755

Query: 1780 --LQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPN 1837
              ++ +R G++Y + V A++   E  P   TQ   +  P +    ++  +          
Sbjct: 8756 YTVKEIREGADYKLRVSAVNAAGEGPP-GETQPVTVAEPQEPPAVELDVS------VKGG 8808

Query: 1838 VQLTGYRVRVTPKEKTG---PMKEINLAP---DSSSVVVSGLMVATKYEVSVYALKDTLT 1891
            +Q+   +    P   TG   P K         D   VV+    V TK E+    +KD L 
Sbjct: 8809 IQIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKDRVVIDN--VGTKSEL---IIKDALR 8863

Query: 1892 SRPAQGVVTTLENVS---PPRRARVTDATETTI------------TISWRTKTE----TI 1932
                + V+T   +        R  V D     +             ++W    +     I
Sbjct: 8864 KDHGRYVITATNSCGSKFAAARVEVFDVPGPVLDLKPVVTNRKMCLLNWSDPEDDGGSEI 8923

Query: 1933 TGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDAST 1992
            TGF ++   A   T  ++ I+ +     ITGL  G +YK  +   N      PV I    
Sbjct: 8924 TGFIIERKDAKMHT-WRQPIETERSKCDITGLLEGQEYKFRVIAKNKFGCGPPVEIGPIL 8982

Query: 1993 AID------APSNLRFLATTPNSLLVSWQPPRAR----ITGYIIKYEKPGSPPREVVPRP 2042
            A+D      +P  L +   T +++ + W+ PR+     I GYII+  +   P  E V + 
Sbjct: 8983 AVDPLGPPTSPERLTYTERTKSTITLDWKEPRSNGGSPIQGYIIEKRRHDKPDFERVNKR 9042

Query: 2043 RPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQ 2084
                T   +  L+    Y   V A+    +SEP +     +Q
Sbjct: 9043 LCPTTSFLVENLDEHQMYEFRVKAVNEIGESEPSLPLNVVIQ 9084



 Score =  144 bits (362), Expect = 1e-33
 Identities = 288/1427 (20%), Positives = 522/1427 (36%), Gaps = 163/1427 (11%)

Query: 696   DFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYE 755
             D+T T+ ++  + +          P    S  + ++ +   ++SW    +        Y 
Sbjct: 13060 DYTITAENSSGSKSATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYI 13119

Query: 756   LSE-EGDEPQYLDLPSTA--TSVNIPDLLPGRKY-----IVNVYQISEDGEQSLILSTSQ 807
             + + E   P +  + +T   TS ++  L+ G +Y       N Y + +       ++ + 
Sbjct: 13120 VDKRETSRPNWAQVSATVPITSCSVEKLIEGHEYQFRICAENKYGVGDPVFTEPAIAKNP 13179

Query: 808   TTAPDAPPDPTVDQVDDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNL-PETA 862
                P     P +  +    + V W  P     +PITGY +    +   + T++N  P   
Sbjct: 13180 YDPPGRCDPPVISNITKDHMTVSWKPPADDGGSPITGYLLEKRETQAVNWTKVNRKPIIE 13239

Query: 863   NSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVK 922
              ++  + LQ G +Y   + A+ +     P    +             P   +  + T   
Sbjct: 13240 RTLKATGLQEGTEYEFRVTAINKAGPGKPSDASKAAYARDPQYPPGPPAFPKVYDTTRSS 13299

Query: 923   VTIMWTPPE----SAVTGYRVDVIPVNLPGEHGQRLPIS-RNTFAEVTGLSPGVTYYFKV 977
             V++ W  P     S + GY V+V   +        LP + + T  EVTGL     Y F+V
Sbjct: 13300 VSLSWGKPAYDGGSPIIGYLVEVKRADSDNWVRCNLPQNLQKTRFEVTGLMEDTQYQFRV 13359

Query: 978   FAVSHGRESKP-----------LTAQQTTKLDAPTNLQFVNETDST----VLVRWTPPRA 1022
             +AV+    S P           +      +LDA      +     T    V V+  PP  
Sbjct: 13360 YAVNKIGYSDPSDVPDKHYPKDILIPPEGELDADLRKTLILRAGVTMRLYVPVKGRPP-P 13418

Query: 1023  QITGYRLTVGLTRR-GQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGV 1081
             +IT  +  V L  R G   +     +  +    N   A +Y ++L    G +E      V
Sbjct: 13419 KITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKYILTLENSCGKKEYTIVVKV 13478

Query: 1082  FTTLQPGSSIPPYNTEVTETTIVITWTP------APRIGFKLGVRPSQGGEAPREVTSDS 1135
               T  PG  +     E+++ +  +TW P      +P I + +  R ++        T  S
Sbjct: 13479 LDT--PGPPVNVTVKEISKDSAYVTWEPPIIDGGSPIINYVVQKRDAERKSWSTVTTECS 13536

Query: 1136  -GSIVVSGLTPGVEYVYTIQVLRD------GQERDAPIVNKVVTPLSPPTNLHLEANPDT 1188
               S  V+ L  G  Y + +    +      G+ RDA  V    TP  P  +L + +   +
Sbjct: 13537 KTSFRVANLEEGKSYFFRVFAENEYGIGDPGETRDA--VKASQTP-GPVVDLKVRSVSKS 13593

Query: 1189  GVLTVSWERSTTPD---ITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNV 1245
                ++ W++  +     I GY +        + N  + V+ +     +  +L+ G EY  
Sbjct: 13594 S-CSIGWKKPHSDGGSRIIGYVVDFL----TEENKWQRVMKSLSLQYSAKDLTEGKEYTF 13648

Query: 1246  SVYTVKDDKESVPISDTIIP---------EVPQLTDLSFVDITDSSIGLR---------- 1286
              V    ++ E  P   T++          ++  L DL ++   +S+  L+          
Sbjct: 13649 RVSAENENGEGTPSEITVVARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPIKGKPAPS 13708

Query: 1287  --WTPLNSSTIIGYRITVVAAGEGIP-IFEDFVDSSVGYYTVTGLEPGIDYDISVITLIN 1343
               W           R++V ++      I  D   S  G YT+T        + ++   + 
Sbjct: 13709 VSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKEGTISIKVV 13768

Query: 1344  GGESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAPPP---SIDLTNFLVRYSPVKNEE 1400
             G    PT             ++F  +  + M + WAPP      ++TN+++      N +
Sbjct: 13769 GKPGIPT-----------GPIKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDSVNNK 13817

Query: 1401  DVAELSISPSDNAVVLTNLLPGTEYVVSVSS-----VYEQHESTPLRGRQKTGL-DSPTG 1454
              V   S +       +T L  G EY   VS+     V E  +S P+  R    + D+P  
Sbjct: 13818 WVTCAS-AVQKTTFRVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVPDAPPP 13876

Query: 1455  IDFSDITANSFTVHWIAPRAT----ITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLT 1510
              +  D+  +S ++ W  P+ T    ITGY +     +     R ++ P       +T LT
Sbjct: 13877 PNIVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTPIRMRDFKVTGLT 13936

Query: 1511  PGTEYVVSIVALN----GREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAV-- 1564
              G EY   ++A+N    G+   P          D P   EV+  T  S+ + W  P    
Sbjct: 13937 EGLEYEFRVMAINLAGVGKPSLPSEPVVALDPIDPPGKPEVINITRNSVTLIWTEPKYDG 13996

Query: 1565  --TVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASS 1622
                +  Y +   +    S ++   V   +   T++ L  G  Y   + A    G   A S
Sbjct: 13997 GHKLTGYIVEKRDLPSKSWMKANHVNVPECAFTVTDLVEGGKYEFRIRAKNTAGAISAPS 14056

Query: 1623  KPI-SINYRTEIDKPSQMQVTDVQD------------NSISV--KWLPSSS-PVTGYRVT 1666
             +   +I  + E + P+ +    ++D            N+IS+  K LP SS    G  + 
Sbjct: 14057 ESTETIICKDEYEAPTIVLDPTIKDGLTIKAGDTIVLNAISILGKPLPKSSWSKAGKDIR 14116

Query: 1667  TTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRP 1726
                   P      T+ P  + +TI+          ++ A NP G     V+  V ++  P
Sbjct: 14117 ------PSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFGTKVEHVKVTVLDVPGP 14170

Query: 1727  KG-LAFTDVDVDSIKIAWESP---QGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQG 1782
              G +  ++V  +   + W  P    G   +  +        +     + D +        
Sbjct: 14171 PGPVEISNVSAEKATLTWTPPLEDGGSPIKSYILEKRETSRLLWTVVSEDIQSCRHVATK 14230

Query: 1783  LRPGSEYTVSVVALH-----DDMESQPLIGTQSTAIPAPTDL-KFTQVTPTSLSAQWTPP 1836
             L  G+EY   V A++     + ++S+P+        P P +  + + VT  + +  W  P
Sbjct: 14231 LIQGNEYIFRVSAVNHYGKGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSWKRP 14290

Query: 1837  ----NVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTS 1892
                   ++TGY V    K+    ++ I          V+GL   + YE  V A       
Sbjct: 14291 VDDGGSEITGYHVERREKKSLRWVRAIKTPVSDLRCKVTGLQEGSTYEFRVSAENRAGIG 14350

Query: 1893  RPAQGVVTTLEN-----VSPPRRARVTDATETTITISWRTKTE----TITGFQVDAVPAN 1943
              P++   + L         PP    VTD T+ + +++W          ITG+ V+     
Sbjct: 14351 PPSEASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLAWGKPHYDGGLEITGYVVEHQKVG 14410

Query: 1944  GQTPIQRTIKPDVR--SYTITGLQPGTDYKIYLYTLNDNARSSPVVI 1988
              +  I+ T    +R   + +  LQ    Y   +  +ND     P VI
Sbjct: 14411 DEAWIKDTTGTALRITQFVVPDLQTKEKYNFRISAINDAGVGEPAVI 14457



 Score =  136 bits (342), Expect = 3e-31
 Identities = 287/1435 (20%), Positives = 516/1435 (35%), Gaps = 196/1435 (13%)

Query: 794   SEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ----APITGYRIVYSPSV 849
             +  G +S  +       P  P    ++++     ++ W  P     + IT Y +    + 
Sbjct: 13067 NSSGSKSATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYIVDKRETS 13126

Query: 850   EGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPS 909
               +  +++      S ++  L  G +Y   I A  +     PV  +      P     P 
Sbjct: 13127 RPNWAQVSATVPITSCSVEKLIEGHEYQFRICAENKYGVGDPVFTEPAIAKNPYDP--PG 13184

Query: 910   PRDLQFVE-VTDVKVTIMWTPPE----SAVTGYRVDVIPVNLPG-EHGQRLPISRNTFAE 963
               D   +  +T   +T+ W PP     S +TGY ++             R PI   T  +
Sbjct: 13185 RCDPPVISNITKDHMTVSWKPPADDGGSPITGYLLEKRETQAVNWTKVNRKPIIERTL-K 13243

Query: 964   VTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKL-------DAPTNLQFVNETDSTVLVR 1016
              TGL  G  Y F+V A++     KP  A +             P   +  + T S+V + 
Sbjct: 13244 ATGLQEGTEYEFRVTAINKAGPGKPSDASKAAYARDPQYPPGPPAFPKVYDTTRSSVSLS 13303

Query: 1017  WTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSVSK--YPLRNLQPASEYTVSLVAIK 1070
             W  P     + I GY + V         + N+  ++ K  + +  L   ++Y   + A+ 
Sbjct: 13304 WGKPAYDGGSPIIGYLVEVKRADSDNWVRCNLPQNLQKTRFEVTGLMEDTQYQFRVYAVN 13363

Query: 1071  GNQESPKATGVFTTLQPGSSIPP---YNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEA 1127
                 S  +            IPP    + ++ +T I+       R G  + +     G  
Sbjct: 13364 KIGYSDPSDVPDKHYPKDILIPPEGELDADLRKTLIL-------RAGVTMRLYVPVKGRP 13416

Query: 1128  PREVTSDSGSIVVS---GLT------------------PGVEYVYTIQVLRDGQERDAPI 1166
             P ++T    ++ +    GL                      +Y+ T++      +++  I
Sbjct: 13417 PPKITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKYILTLE--NSCGKKEYTI 13474

Query: 1167  VNKVVTPLSPPTNLHL-EANPDTGVLTVSWERSTTPDITG----YRITTTPTNGQQGNSL 1221
             V KV+    PP N+ + E + D+  +T  WE    P I G            + ++ +  
Sbjct: 13475 VVKVLDTPGPPVNVTVKEISKDSAYVT--WE---PPIIDGGSPIINYVVQKRDAERKSWS 13529

Query: 1222  EEVVHADQSSCTFDNLSPGLEYNVSVYTVKD--------DKESVPISDTIIPEVPQLTDL 1273
                    ++S    NL  G  Y   V+   +         +++V  S T  P V    DL
Sbjct: 13530 TVTTECSKTSFRVANLEEGKSYFFRVFAENEYGIGDPGETRDAVKASQTPGPVV----DL 13585

Query: 1274  SFVDITDSSIGLRWTPLNS---STIIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEP 1330
                 ++ SS  + W   +S   S IIGY +  +        ++  + S    Y+   L  
Sbjct: 13586 KVRSVSKSSCSIGWKKPHSDGGSRIIGYVVDFLTEENK---WQRVMKSLSLQYSAKDLTE 13642

Query: 1331  GIDYDISVITLINGGESAPTTLT---QQTAVPPPTDLRFTNIGPDT-------------M 1374
             G +Y   V      GE  P+ +T   +   V P  DL+     PD              +
Sbjct: 13643 GKEYTFRVSAENENGEGTPSEITVVARDDVVAPDLDLKGL---PDLCYLAKENSNFRLKI 13699

Query: 1375  RVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLL-------PGTEYVV 1427
              +   P PS+         S  K E+ +A  +    +++ V T L+          +Y +
Sbjct: 13700 PIKGKPAPSV---------SWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTI 13750

Query: 1428  SVSSVYEQHEST-PLRGRQKTGLDSPTG-IDFSDITANSFTVHWIAPR----ATITGYRI 1481
             ++ +V    E T  ++   K G+  PTG I F ++TA + T+ W  P+    + IT Y I
Sbjct: 13751 TLKNVAGTKEGTISIKVVGKPGI--PTGPIKFDEVTAEAMTLKWAPPKDDGGSEITNY-I 13807

Query: 1482  RHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN------GREESPLLIGQQ 1535
                 +  + +         + +  +T L  G EY   + A N      G +  P++    
Sbjct: 13808 LEKRDSVNNKWVTCASAVQKTTFRVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHP 13867

Query: 1536  STVSDVPRDLEVVAATPTSLLISWDAPAVT----VRYYRITYGETGGNSPVQEFTVPGSK 1591
               V D P    +V     S+ ++W  P  T    +  Y + + E       +    P   
Sbjct: 13868 FDVPDAPPPPNIVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTPIRM 13927

Query: 1592  STATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISV 1651
                 ++GL  G++Y   V A+   G    S     +     ID P + +V ++  NS+++
Sbjct: 13928 RDFKVTGLTEGLEYEFRVMAINLAGVGKPSLPSEPVVALDPIDPPGKPEVINITRNSVTL 13987

Query: 1652  KWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQN 1707
              W          +TGY V           K       +   T+  L    +Y   + A+N
Sbjct: 13988 IWTEPKYDGGHKLTGYIVEKRDLPSKSWMKANHVNVPECAFTVTDLVEGGKYEFRIRAKN 14047

Query: 1708  PSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQV----------------S 1751
              +G      ++  T I + +  A T V   +IK       G                  S
Sbjct: 14048 TAGAISAPSESTETIICKDEYEAPTIVLDPTIKDGLTIKAGDTIVLNAISILGKPLPKSS 14107

Query: 1752  RYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQST 1811
               +         I ++   P     T +    +   EYT++             +     
Sbjct: 14108 WSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFGTKVEHVKVTVLDV 14167

Query: 1812  AIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVR--VTPKEKTGPMKEINLAPDSSSV- 1868
               P P  ++ + V+    +  WTPP ++  G  ++  +  K +T  +    ++ D  S  
Sbjct: 14168 PGP-PGPVEISNVSAEKATLTWTPP-LEDGGSPIKSYILEKRETSRLLWTVVSEDIQSCR 14225

Query: 1869  -VVSGLMVATKYEVSVYALKDTLTSRPAQG----VVTTLENVSPPRRARVTDATETTITI 1923
              V + L+   +Y   V A+       P Q     +V       PP +  V++ T+ T T+
Sbjct: 14226 HVATKLIQGNEYIFRVSAVNHYGKGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTATV 14285

Query: 1924  SWRTKTE----TITGFQVDAVPANGQTPIQRTIKPDVRSY--TITGLQPGTDYKIYLYTL 1977
             SW+   +     ITG+ V+         + R IK  V      +TGLQ G+ Y+  +   
Sbjct: 14286 SWKRPVDDGGSEITGYHVERREKKSLRWV-RAIKTPVSDLRCKVTGLQEGSTYEFRVSAE 14344

Query: 1978  N-------DNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYII 2026
             N         A  S ++ DA+     PSN     TT  S  ++W  P       ITGY++
Sbjct: 14345 NRAGIGPPSEASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLAWGKPHYDGGLEITGYVV 14404

Query: 2027  KYEKPGSPPREVVPRPRPG----VTEATITGLEPGTEYTIYVIALKNNQKSEPLI 2077
             +++K G    E   +   G    +T+  +  L+   +Y   + A+ +    EP +
Sbjct: 14405 EHQKVGD---EAWIKDTTGTALRITQFVVPDLQTKEKYNFRISAINDAGVGEPAV 14456



 Score =  133 bits (335), Expect = 2e-30
 Identities = 325/1621 (20%), Positives = 584/1621 (36%), Gaps = 231/1621 (14%)

Query: 628   IQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISI 684
             + W  P     S I+ Y+L  R   +V   K    P    +    GL+ G  YE ++ +I
Sbjct: 13201 VSWKPPADDGGSPITGYLLEKRETQAVNWTKVNRKPIIERTLKATGLQEGTEYEFRVTAI 13260

Query: 685   QQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSW---- 740
              + G  + +              S         + P       V + T SS  +SW    
Sbjct: 13261 NKAGPGKPSD------------ASKAAYARDPQYPPGPPAFPKVYDTTRSSVSLSWGKPA 13308

Query: 741   VSASDTVSGFRVEYELSEEGDEPQYLDLPSTA--TSVNIPDLLPGRKYIVNVYQISEDGE 798
                   + G+ VE + ++  D     +LP     T   +  L+   +Y   VY +++ G 
Sbjct: 13309 YDGGSPIIGYLVEVKRADS-DNWVRCNLPQNLQKTRFEVTGLMEDTQYQFRVYAVNKIGY 13367

Query: 799   QSLILSTSQTTAPDA--------PPDPTVDQVDDTSIVVRWS---RPQAPITGYRIVYSP 847
                   +  +  PD         PP+  +D     ++++R     R   P+ G      P
Sbjct: 13368 ------SDPSDVPDKHYPKDILIPPEGELDADLRKTLILRAGVTMRLYVPVKGRP---PP 13418

Query: 848   SVEGSSTELNLPETAN-SVTLSDLQPGVQ-----------YNITIYAVEENQESTPVVIQ 895
              +  S   +NL +     +  +D    ++           Y +T+      +E T VV  
Sbjct: 13419 KITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKYILTLENSCGKKEYTIVVKV 13478

Query: 896   QETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPGEHG 951
              +T G P + TV         E++     + W PP     S +  Y V            
Sbjct: 13479 LDTPGPPVNVTVK--------EISKDSAYVTWEPPIIDGGSPIINYVVQKRDAERKSWST 13530

Query: 952   QRLPISRNTFAEVTGLSPGVTYYFKVFAVSH---GRESKPLTAQQTTKLDAPT-NLQFVN 1007
                  S+ +F  V  L  G +Y+F+VFA +    G   +   A + ++   P  +L+  +
Sbjct: 13531 VTTECSKTSF-RVANLEEGKSYFFRVFAENEYGIGDPGETRDAVKASQTPGPVVDLKVRS 13589

Query: 1008  ETDSTVLVRWTPPRA----QITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYT 1063
              + S+  + W  P +    +I GY +   LT   + ++     S+ +Y  ++L    EYT
Sbjct: 13590 VSKSSCSIGWKKPHSDGGSRIIGYVVDF-LTEENKWQRVMKSLSL-QYSAKDLTEGKEYT 13647

Query: 1064  VSLVAIKGNQE-SPKATGVFT---TLQPG---SSIPPYNTEVTETT-----IVITWTPAP 1111
               + A   N E +P    V      + P      +P       E +     I I   PAP
Sbjct: 13648 FRVSAENENGEGTPSEITVVARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPIKGKPAP 13707

Query: 1112  RIGFKLGVRP-SQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKV 1170
              + +K G  P +       E ++ + +++V          YTI +      ++  I  KV
Sbjct: 13708 SVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKEGTISIKV 13767

Query: 1171  VTPLSPPTNLHLEANPDTGVLTVSW---ERSTTPDITGYRITTTPTNGQQGNSLEEVVHA 1227
             V     PT            +T+ W   +     +IT Y +    +   +  +    V  
Sbjct: 13768 VGKPGIPTGPIKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDSVNNKWVTCASAVQK 13827

Query: 1228  DQSSCTFDNLSPGLEYNVSV-----YTVKDDKESVPI---SDTIIPEVPQLTDLSFVDIT 1279
                  T   L  G+EY   V     Y V +  +S PI       +P+ P   ++  VD+ 
Sbjct: 13828 TTFRVT--RLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVPDAPPPPNI--VDVR 13883

Query: 1280  DSSIGLRWTP---LNSSTIIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDI 1336
               S+ L WT       S I GY +        +    +     +  + VTGL  G++Y+ 
Sbjct: 13884 HDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTPIRMRDFKVTGLTEGLEYEF 13943

Query: 1337  SVITLINGGESAPTTLTQQTA----VPPPTDLRFTNIGPDTMRVTWAPPP---SIDLTNF 1389
              V+ +   G   P+  ++       + PP      NI  +++ + W  P       LT +
Sbjct: 13944 RVMAINLAGVGKPSLPSEPVVALDPIDPPGKPEVINITRNSVTLIWTEPKYDGGHKLTGY 14003

Query: 1390  LVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVV---------SVSSVYEQHESTP 1440
             +V    + ++  +    ++  + A  +T+L+ G +Y           ++S+  E  E+  
Sbjct: 14004 IVEKRDLPSKSWMKANHVNVPECAFTVTDLVEGGKYEFRIRAKNTAGAISAPSESTETII 14063

Query: 1441  LRGRQK--TGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVP 1498
              +   +  T +  PT  D   I A    V       +I G  +   P+    +  +D  P
Sbjct: 14064 CKDEYEAPTIVLDPTIKDGLTIKAGDTIV---LNAISILGKPL---PKSSWSKAGKDIRP 14117

Query: 1499  HSRNSITLTNLTP-----------GTEYVVSIVALNGREESPLLIGQQSTVSDVPRD--- 1544
                  IT T  +              EY ++     G +   + +    TV DVP     
Sbjct: 14118 SDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFGTKVEHVKV----TVLDVPGPPGP 14173

Query: 1545  LEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATI-------- 1596
             +E+   +     ++W  P            E GG SP++ + +   +++  +        
Sbjct: 14174 VEISNVSAEKATLTWTPPL-----------EDGG-SPIKSYILEKRETSRLLWTVVSEDI 14221

Query: 1597  -------SGLKPGVDYTITVYAVT--GRGDSPASSKPISINYRT-EIDKPSQMQVTDVQD 1646
                    + L  G +Y   V AV   G+G+ P  S+P+ +  R      P + +V++V  
Sbjct: 14222 QSCRHVATKLIQGNEYIFRVSAVNHYGKGE-PVQSEPVKMVDRFGPPGPPEKPEVSNVTK 14280

Query: 1647  NSISVKWL----PSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVS 1702
             N+ +V W        S +TGY V    K      +            + GLQ    Y   
Sbjct: 14281 NTATVSWKRPVDDGGSEITGYHVERREKKSLRWVRAIKTPVSDLRCKVTGLQEGSTYEFR 14340

Query: 1703  VYAQNPSGESQP-------LVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQG----QVS 1751
             V A+N +G   P       L++ A      P     TD    S  +AW  P      +++
Sbjct: 14341 VSAENRAGIGPPSEASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLAWGKPHYDGGLEIT 14400

Query: 1752  RYRVTYSSPEDGIHELFPAPDGEEDTA-ELQGLRPGSEYTVSVVALHDDMESQPLIGTQS 1810
              Y V +    D              T   +  L+   +Y   + A++D    +P +    
Sbjct: 14401 GYVVEHQKVGDEAWIKDTTGTALRITQFVVPDLQTKEKYNFRISAINDAGVGEPAV---- 14456

Query: 1811  TAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDS----- 1865
               IP    ++        L A+     V   G  +R+    K  P  E+    D+     
Sbjct: 14457 --IPDVEIVEREMAPDFELDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKN 14514

Query: 1866  -------SSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTT--LENVSPPRRARVTDA 1916
                     S  +  +    +Y+   + +     +    G V    L+   P    R TD 
Sbjct: 14515 RANIENTESFTLLIIPECNRYDTGKFVMTIENPAGKKSGFVNVRVLDTPGPVLNLRPTDI 14574

Query: 1917  TETTITISWRTKT----ETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKI 1972
             T+ ++T+ W          IT + V+   A  ++    T K    +Y +TGL  G +Y  
Sbjct: 14575 TKDSVTLHWDLPLIDGGSRITNYIVEKREATRKSYSTATTKCHKCTYKVTGLSEGCEYFF 14634

Query: 1973  YLYTLNDNARSSPVV----IDASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGY 2024
              +   N+     P      + AS A   P +L  +  T +++ ++W  P+    ++ITGY
Sbjct: 14635 RVMAENEYGIGEPTETTEPVKASEAPSPPDSLNIMDITKSTVSLAWPKPKHDGGSKITGY 14694

Query: 2025  IIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQ 2084
             +I+ ++ GS     +   +    E  +  L  G EYT  V+A+ +  +S P   R   V+
Sbjct: 14695 VIEAQRKGSDQWTHITTVKG--LECVVRNLTEGEEYTFQVMAVNSAGRSAPRESRPVIVK 14752

Query: 2085  K 2085
             +
Sbjct: 14753 E 14753



 Score =  128 bits (322), Expect = 6e-29
 Identities = 343/1604 (21%), Positives = 574/1604 (35%), Gaps = 260/1604 (16%)

Query: 611   PVEVFITETPSQPNSHPIQWNAPQ---PSHISKYILRWRPKNSVGRWKEATIPGHLNS-- 665
             P ++ I +  S  +S  + W+ P     S ++ Y++  R +     W   +  G + +  
Sbjct: 20865 PAKIRIAD--STKSSITLGWSKPVYDGGSAVTGYVVEIR-QGEEEEWTTVSTKGEVRTTE 20921

Query: 666   YTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATS 725
             Y +  LKPGV Y  ++ ++   G  E    +    +                 S +    
Sbjct: 20922 YVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQAKDILEAPEIDLDVALRTSVIAKAG 20981

Query: 726   ESVTEITASSF----VVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLL 781
             E V  +          V+W      + G    Y + E  D    L +P    +       
Sbjct: 20982 EDVQVLIPFKGRPPPTVTWRKDEKNL-GSDARYSI-ENTDSSSLLTIPQVTRNDT----- 21034

Query: 782   PGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ----AP 837
                KYI+ +     + + S + S      P A     V  V   ++ + W  P     +P
Sbjct: 21035 --GKYILTIENGVGEPKSSTV-SVKVLDTPAACQKLQVKHVSRGTVTLLWDPPLIDGGSP 21091

Query: 838   ITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQE 897
             I  Y I    + + + + ++   ++ S  L DL     +   + A  E     P     E
Sbjct: 21092 IINYVIEKRDATKRTWSVVSHKCSSTSFKLIDLSEKTPFFFRVLAENEIGIGEPC----E 21147

Query: 898   TTGTPRSDTVPSP-RDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPVNLPGEHG- 951
             TT   ++  VP+P RDL   + T   V + WT P+    S +T Y   V+     GE   
Sbjct: 21148 TTEPVKAAEVPAPIRDLSMKDSTKTSVILSWTKPDFDGGSVITEY---VVERKGKGEQTW 21204

Query: 952   QRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDS 1011
                 IS+    EV+ L       F+VFA +    S P+T    T  +    L    E D 
Sbjct: 21205 SHAGISKTCEIEVSQLKEQSVLEFRVFAKNEKGLSDPVTIGPITVKE----LIITPEVDL 21260

Query: 1012  TVLVRWTPPRAQIT---GYRLTVGLTRRGQPRQYNVGPSVS----KYPLRNLQ------P 1058
             + +     P AQ+T   G+ + + L  +G+P+     PS+S      PL+  +       
Sbjct: 21261 SDI-----PGAQVTVRIGHNVHLELPYKGKPK-----PSISWLKDGLPLKESEFVRFSKT 21310

Query: 1059  ASEYTVSLVAIKGNQESPKATGVFT-------------TLQPGSSI--PPYNTEVTETTI 1103
              ++ T+S+   K  +   K T +               TL P S    P    E+   ++
Sbjct: 21311 ENKITLSIKNAK-KEHGGKYTVILDNAVCRIAVPITVITLGPPSKPKGPIRFDEIKADSV 21369

Query: 1104  VITWTPAPRIGFKLGVRPSQGGEAP------REVTSDSGSIVVSG----------LTPGV 1147
             +++W      G         GGE        RE +  +  +V S           L    
Sbjct: 21370 ILSWDVPEDNG---------GGEITCYSIEKRETSQTNWKMVCSSVARTTFKVPNLVKDA 21420

Query: 1148  EYVYTIQVLRDGQERDAPIVNKVVTP-----LSPPTNLHLEANPDTGVLTVSWERSTTP- 1201
             EY + ++   +      P+V+ ++       +  P    +  N  +  ++++W+      
Sbjct: 21421 EYQFRVRA-ENRYGVSQPLVSSIIVAKHQFRIPGPPGKPVIYNVTSDGMSLTWDAPVYDG 21479

Query: 1202  --DITGYRITTTPTNG---QQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKES 1256
               ++TG+ +     N    Q+ N+    +   +   T   L  GL+Y   VY       S
Sbjct: 21480 GSEVTGFHVEKKERNSILWQKVNT--SPISGREYRAT--GLVEGLDYQFRVYAENSAGLS 21535

Query: 1257  VPISDT-----IIPEVPQLTDLSFVDITDSSIGLRWTPL---NSSTIIGYRITVVAAGEG 1308
              P   +     + P  P  T   ++D+T  +I L+W P      S I+GY I      E 
Sbjct: 21536 SPSDPSKFTLAVSPVDPPGTP-DYIDVTRETITLKWNPPLRDGGSKIVGYSIEKRQGNER 21594

Query: 1309  IPIFEDFVDSSVGYYTVTGLEPGIDYDISVI------TLINGGESAPTTLTQQTAVPPPT 1362
               +  +F D S   YTVTGL PG  Y+  +I      T+    +S+   +T+   VPP  
Sbjct: 21595 W-VRCNFTDVSECQYTVTGLSPGDRYEFRIIARNAVGTISPPSQSSGIIMTRDENVPP-- 21651

Query: 1363  DLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNE---EDVAELSISPSDNAVVLTNL 1419
                    GP+                 LV+  PV      +D  E+    +   + +T++
Sbjct: 21652 ---IVEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMN---MEITDV 21705

Query: 1420  LPGTEYVV--------SVSSVYEQHESTPLRGRQKTGLDSPTG-----IDFSDITANSFT 1466
             L  T   V         V +V  ++ S   +   K  +    G     I F++IT    T
Sbjct: 21706 LGSTSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQDTPGKVVGPIRFTNITGEKMT 21765

Query: 1467  VHWIAPR----ATITGYRI-RHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVA 1521
             + W AP     A IT Y I +      +    ED+      S T   L  G EY   + A
Sbjct: 21766 LWWDAPLNDGCAPITHYIIEKRETSRLAWALIEDKC--EAQSYTAIKLINGNEYQFRVSA 21823

Query: 1522  LN----GR--EESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGE 1575
             +N    GR  +  P++   Q TV D P   E    T  S+ ++W  P            E
Sbjct: 21824 VNKFGVGRPLDSDPVVAQIQYTVPDAPGIPEPSNITGNSITLTWARP------------E 21871

Query: 1576  TGGNSPVQEFTV-----------------PGSKSTATISGLKPGVDYTITVYAVTGRGDS 1618
             + G S +Q++ +                 P S++   ++GL  G +Y   V A    G  
Sbjct: 21872 SDGGSEIQQYILERREKKSTRWVKVISKRPISETRFKVTGLTEGNEYEFHVMAENAAGVG 21931

Query: 1619  PASSKPISINYRTEIDKPSQ---MQVTDVQDNSISVKW----LPSSSPVTGYRVTTTPKN 1671
             PAS     I  R  ++ P     ++VTD    ++S++W          + GY +     +
Sbjct: 21932 PASGISRLIKCREPVNPPGPPTVVKVTDTSKTTVSLEWSKPVFDGGMEIIGYIIEMCKAD 21991

Query: 1672  GPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTA-VTNIDRPKGLA 1730
                  K       +T  T+  LQ   EY   V A N +G+      T  +  +DR   L 
Sbjct: 21992 LGDWHKVNAEACVKTRYTVTDLQAGEEYKFRVSAINGAGKGDSCEVTGTIKAVDR---LT 22048

Query: 1731  FTDVDVDS-IKIAWESPQGQVSRYRVTY----------SSPEDGIH---ELFPAPDGEED 1776
               ++D+D+  K       G   R  + Y          S P+  +    ++         
Sbjct: 22049 APELDIDANFKQTHVVRAGASIRLFIAYQGRPTPTAVWSKPDSNLSLRADIHTTDSFSTL 22108

Query: 1777  TAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPP 1836
             T E        +YT++V            +    T  P P  + F  VT  S +  W  P
Sbjct: 22109 TVENCNRNDAGKYTLTVENNSGSKSITFTVKVLDTPGP-PGPITFKDVTRGSATLMWDAP 22167

Query: 1837  NVQLTGYRVRVTPKEKTGPMKE----INLAPDSSSVVVSGLMVATKYEVSVYALKDTLTS 1892
              +   G R+     EK    +     I+         V+ L     Y   V A+ +    
Sbjct: 22168 LLD-GGARIHHYVVEKREASRRSWQVISEKCTRQIFKVNDLAEGVPYYFRVSAVNEYGVG 22226

Query: 1893  RPAQ--GVVTTLENVSPPRRARVTDATETTITISW----RTKTETITGFQVDAVPANGQT 1946
              P +    +   E  +PPRR  V D ++++  ++W          ITG+ ++        
Sbjct: 22227 EPYEMPEPIVATEQPAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSDF 22286

Query: 1947  PIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATT 2006
              ++      + ++T+  L   T+Y+  +   ND   S P    +S  I  P         
Sbjct: 22287 WVEAGHTKQL-TFTVERLVEKTEYEFRVKAKNDAGYSEPREAFSSVIIKEPQ------IE 22339

Query: 2007  PNSLLVSWQPPRARITGYIIKYEKPGSPPREVVP---RPRPGVT 2047
             P + L         IT  +I   K GSP    VP   RP P VT
Sbjct: 22340 PTADLTG-------ITNQLITC-KAGSPFTIDVPISGRPAPKVT 22375



 Score =  124 bits (311), Expect = 1e-27
 Identities = 291/1338 (21%), Positives = 513/1338 (38%), Gaps = 174/1338 (13%)

Query: 780   LLPGRKYI-----VNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRP 834
             ++ G +YI     VN Y I E  E   +++ +    P  P  P V ++   S+ V WSRP
Sbjct: 20725 IIKGNEYIFRVRAVNKYGIGEPLESDSVVAKNAFVTPGPPGIPEVTKITKNSMTVVWSRP 20784

Query: 835   QA----PITGYRIVYSPSVEGSSTEL---NLPETANSVTLSDLQPGVQYNI-TIYAVEEN 886
              A     I+GY +           ++    + +T   VT        QY +  + A  + 
Sbjct: 20785 IADGGSDISGYFLEKRDKKSLGWFKVLKETIRDTRQKVTGLTENSDYQYRVCAVNAAGQG 20844

Query: 887   QESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVI 942
               S P    +        D    P  ++  + T   +T+ W+ P     SAVTGY V++ 
Sbjct: 20845 PFSEP---SEFYKAADPIDPPGPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVVEI- 20900

Query: 943   PVNLPGEHGQRLPIS-----RNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTK- 996
                  GE  +   +S     R T   V+ L PGV YYF+V AV+   + +P+   +  + 
Sbjct: 20901 ---RQGEEEEWTTVSTKGEVRTTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQA 20957

Query: 997   ---LDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQP--------RQYNVG 1045
                L+AP       E D  V +R T   A+  G  + V +  +G+P         + N+G
Sbjct: 20958 KDILEAP-------EIDLDVALR-TSVIAK-AGEDVQVLIPFKGRPPPTVTWRKDEKNLG 21008

Query: 1046  PSVSKYPLRNLQPASEYTVS----------LVAIKGNQESPKATGVFTTL--QPGSSIPP 1093
              S ++Y + N   +S  T+           ++ I+     PK++ V   +   P +    
Sbjct: 21009 -SDARYSIENTDSSSLLTIPQVTRNDTGKYILTIENGVGEPKSSTVSVKVLDTPAACQKL 21067

Query: 1094  YNTEVTETTIVITWTP------APRIGFKLGVRPS---QGGEAPREVTSDSGSIV-VSGL 1143
                 V+  T+ + W P      +P I + +  R +          + +S S  ++ +S  
Sbjct: 21068 QVKHVSRGTVTLLWDPPLIDGGSPIINYVIEKRDATKRTWSVVSHKCSSTSFKLIDLSEK 21127

Query: 1144  TPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDI 1203
             TP    V     +  G+  +     K     +P  +L ++ +  T V+ +SW   T PD 
Sbjct: 21128 TPFFFRVLAENEIGIGEPCETTEPVKAAEVPAPIRDLSMKDSTKTSVI-LSW---TKPDF 21183

Query: 1204  TGYRITTTPTNGQQGNSLEEVVHADQS-SCTFD----NLSPGLEYNVSVYTVKDDKESVP 1258
              G  + T     ++G   +   HA  S +C  +         LE+ V     K   + V 
Sbjct: 21184 DGGSVITEYVVERKGKGEQTWSHAGISKTCEIEVSQLKEQSVLEFRVFAKNEKGLSDPVT 21243

Query: 1259  ISDTIIPEVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGY----RITVVAAGEGIPIFE- 1313
             I    + E+    ++   DI  + + +R    N    + Y    + ++    +G+P+ E 
Sbjct: 21244 IGPITVKELIITPEVDLSDIPGAQVTVR-IGHNVHLELPYKGKPKPSISWLKDGLPLKES 21302

Query: 1314  DFVDSSVGYYTVT------GLEPGIDYDISVITLINGGESAPTTLTQQTAVPPPTDLRFT 1367
             +FV  S     +T        E G  Y + +   +       T +T      P   +RF 
Sbjct: 21303 EFVRFSKTENKITLSIKNAKKEHGGKYTVILDNAVCRIAVPITVITLGPPSKPKGPIRFD 21362

Query: 1368  NIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSI---SPSDNAVVLTNLLPGTE 1424
              I  D++ ++W  P   +    +  YS  K E       +   S +     + NL+   E
Sbjct: 21363 EIKADSVILSWDVPED-NGGGEITCYSIEKRETSQTNWKMVCSSVARTTFKVPNLVKDAE 21421

Query: 1425  YVVSVSSVYEQHESTPL-----RGRQKTGLDSPTGID-FSDITANSFTVHWIAP----RA 1474
             Y   V +      S PL       + +  +  P G     ++T++  ++ W AP     +
Sbjct: 21422 YQFRVRAENRYGVSQPLVSSIIVAKHQFRIPGPPGKPVIYNVTSDGMSLTWDAPVYDGGS 21481

Query: 1475  TITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQ 1534
              +TG+ +     +     + +  P S      T L  G +Y   + A N    S      
Sbjct: 21482 EVTGFHVEKKERNSILWQKVNTSPISGREYRATGLVEGLDYQFRVYAENSAGLSSPSDPS 21541

Query: 1535  QSTVS----DVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYG---ETGGNSPVQEFTV 1587
             + T++    D P   + +  T  ++ + W+ P        + Y      G    V+    
Sbjct: 21542 KFTLAVSPVDPPGTPDYIDVTRETITLKWNPPLRDGGSKIVGYSIEKRQGNERWVRCNFT 21601

Query: 1588  PGSKSTATISGLKPGVDYTITVYAVTGRGD-SPASSKPISINYRTEIDKPSQMQVTDVQD 1646
               S+   T++GL PG  Y   + A    G  SP S     I  R E   P      +  D
Sbjct: 21602 DVSECQYTVTGLSPGDRYEFRIIARNAVGTISPPSQSSGIIMTRDENVPPIVEFGPEYFD 21661

Query: 1647  -------NSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTK----TAGPDQTEMTIEGLQP 1695
                     S+ +K L    PV   RVT   K+G    K      T     T + +     
Sbjct: 21662 GLIIKSGESLRIKALVQGRPVP--RVTWF-KDGVEIEKRMNMEITDVLGSTSLFVRDATR 21718

Query: 1696  TVEYVVSVYAQNPSGESQPLVQTAVTNIDRP----KGLAFTDVDVDSIKIAWESPQGQ-- 1749
                 V +V A+N SG ++  ++  V   D P      + FT++  + + + W++P     
Sbjct: 21719 DHRGVYTVEAKNASGSAKAEIKVKVQ--DTPGKVVGPIRFTNITGEKMTLWWDAPLNDGC 21776

Query: 1750  --VSRYRVTYSSPEDGIHELFPAPDGEEDTAELQG-----LRPGSEYTVSVVALHD---- 1798
               ++ Y +           L       ED  E Q      L  G+EY   V A++     
Sbjct: 21777 APITHYIIEKRETSRLAWALI------EDKCEAQSYTAIKLINGNEYQFRVSAVNKFGVG 21830

Query: 1799  -DMESQPLIGTQSTAIP-APTDLKFTQVTPTSLSAQWTPP----NVQLTGYRVRVTPKEK 1852
               ++S P++      +P AP   + + +T  S++  W  P      ++  Y +    K+ 
Sbjct: 21831 RPLDSDPVVAQIQYTVPDAPGIPEPSNITGNSITLTWARPESDGGSEIQQYILERREKKS 21890

Query: 1853  TGPMKEINLAPDSSS-VVVSGLMVATKYEVSVYALKDTLTSRPAQGV---VTTLENVS-- 1906
             T  +K I+  P S +   V+GL    +YE  V A ++     PA G+   +   E V+  
Sbjct: 21891 TRWVKVISKRPISETRFKVTGLTEGNEYEFHVMA-ENAAGVGPASGISRLIKCREPVNPP 21949

Query: 1907  -PPRRARVTDATETTITISWRTKT----ETITGFQVDAVPANGQTPIQRTIKPDVRS-YT 1960
              PP   +VTD ++TT+++ W          I G+ ++   A+     +   +  V++ YT
Sbjct: 21950 GPPTVVKVTDTSKTTVSLEWSKPVFDGGMEIIGYIIEMCKADLGDWHKVNAEACVKTRYT 22009

Query: 1961  ITGLQPGTDYKIYLYTLN 1978
             +T LQ G +YK  +  +N
Sbjct: 22010 VTDLQAGEEYKFRVSAIN 22027



 Score =  123 bits (309), Expect = 2e-27
 Identities = 310/1432 (21%), Positives = 508/1432 (35%), Gaps = 230/1432 (16%)

Query: 814   PPDPT-VDQVDDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTLS 868
             PP P  +  V      + W+ P     +PI  Y +    +     T ++    +     +
Sbjct: 14170 PPGPVEISNVSAEKATLTWTPPLEDGGSPIKSYILEKRETSRLLWTVVSEDIQSCRHVAT 14229

Query: 869   DLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVE-VTDVKVTIMW 927
              L  G +Y   + AV    +  PV  Q E          P P +   V  VT    T+ W
Sbjct: 14230 KLIQGNEYIFRVSAVNHYGKGEPV--QSEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSW 14287

Query: 928   TPPE----SAVTGYRVDVIPV-NLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSH 982
               P     S +TGY V+     +L      + P+S +   +VTGL  G TY F+V A + 
Sbjct: 14288 KRPVDDGGSEITGYHVERREKKSLRWVRAIKTPVS-DLRCKVTGLQEGSTYEFRVSAENR 14346

Query: 983   GRESKPLTAQQTTKL-DA------PTNLQFVNETDSTVLVRWTPPR----AQITGYRLTV 1031
                  P  A  +  + DA      P+N    + T  +  + W  P      +ITGY +  
Sbjct: 14347 AGIGPPSEASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLAWGKPHYDGGLEITGYVVEH 14406

Query: 1032  GLTRRGQPRQYNVGPS--VSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGS 1089
                      +   G +  ++++ + +LQ   +Y   + AI        A      +    
Sbjct: 14407 QKVGDEAWIKDTTGTALRITQFVVPDLQTKEKYNFRISAINDAGVGEPAVIPDVEIVERE 14466

Query: 1090  SIPPY--NTEVTETTIVITWTPAPRIGFKLGVR-PSQGGEAPREVTSDSGSIVVSG---- 1142
               P +  + E+  T +V       R G  + +  P +G  AP EVT    +I +      
Sbjct: 14467 MAPDFELDAELRRTLVV-------RAGLSIRIFVPIKGRPAP-EVTWTKDNINLKNRANI 14518

Query: 1143  ---------LTPGVEYVYT---IQVLRDGQERDAPIVN-KVVTPLSPPTNLH-LEANPDT 1188
                      + P      T   +  + +   + +  VN +V+    P  NL   +   D+
Sbjct: 14519 ENTESFTLLIIPECNRYDTGKFVMTIENPAGKKSGFVNVRVLDTPGPVLNLRPTDITKDS 14578

Query: 1189  GVLTVSWERSTTPD---ITGYRITTTPTNGQQGNSLEEVVHADQSSCTFD--NLSPGLEY 1243
               +T+ W+         IT Y +       +  ++     H     CT+    LS G EY
Sbjct: 14579 --VTLHWDLPLIDGGSRITNYIVEKREATRKSYSTATTKCH----KCTYKVTGLSEGCEY 14632

Query: 1244  NVSV-----YTVKDDKESV-PISDTIIPEVPQLTDLSFVDITDSSIGLRWTPLN---SST 1294
                V     Y + +  E+  P+  +  P  P    L+ +DIT S++ L W        S 
Sbjct: 14633 FFRVMAENEYGIGEPTETTEPVKASEAPSPPD--SLNIMDITKSTVSLAWPKPKHDGGSK 14690

Query: 1295  IIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLE-------PGIDYDISVITLINGGES 1347
             I GY I     G          D      TV GLE        G +Y   V+ + + G S
Sbjct: 14691 ITGYVIEAQRKGS---------DQWTHITTVKGLECVVRNLTEGEEYTFQVMAVNSAGRS 14741

Query: 1348  APT----TLTQQTAVPPPTDLR-------FTNIGPDT---MRVTWAPPPSIDLTNFLVRY 1393
             AP      + ++  + P  DLR           G +    + V   P P++         
Sbjct: 14742 APRESRPVIVKEQTMLPELDLRGIYQKLVIAKAGDNIKVEIPVLGRPKPTVTW------- 14794

Query: 1394  SPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGL---- 1449
                K  + + + +   +      + +L   E V S S  Y      PL  R   G     
Sbjct: 14795 ---KKGDQILKQTQRVNFETTATSTILNINECVRSDSGPY------PLTARNIVGEVGDV 14845

Query: 1450  ---------DSPTG-IDFSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPRED 1495
                        PTG I F +++++  T  W  P       I+ Y +       S    E 
Sbjct: 14846 ITIQVHDIPGPPTGPIKFDEVSSDFVTFSWDPPENDGGVPISNYVVEMRQTD-STTWVEL 14904

Query: 1496  RVPHSRNSITLTNLTPGTEYVVSIVALN------GREESPLLIGQQSTVSDVPRDLEVVA 1549
                  R +   T LT G EY   + A N      G   + ++      V   P   +V A
Sbjct: 14905 ATTVIRTTYKATRLTTGLEYQFRVKAQNRYGVGPGITSACIVANYPFKVPGPPGTPQVTA 14964

Query: 1550  ATPTSLLISWDAP----AVTVRYYRITYGETGGN--SPVQEFTVPGSKSTATISGLKPGV 1603
              T  S+ ISW  P       +  Y +   E  G     V +  VPG+   +  SGL  G+
Sbjct: 14965 VTKDSMTISWHEPLSDGGSPILGYHVERKERNGILWQTVSKALVPGNIFKS--SGLTDGI 15022

Query: 1604  DYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKW----LPSSSP 1659
              Y   V A    G S  S     +     ID P +    ++  +++++KW          
Sbjct: 15023 AYEFRVIAENMAGKSKPSKPSEPMLALDPIDPPGKPVPLNITRHTVTLKWAKPEYTGGFK 15082

Query: 1660  VTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQ-- 1717
             +T Y V           K   +   + E T+ GL     Y   V A+N +G   P  +  
Sbjct: 15083 ITSYIVEKRDLPNGRWLKANFSNILENEFTVSGLTEDAAYEFRVIAKNAAGAISPPSEPS 15142

Query: 1718  TAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDT 1777
              A+T  D        DV+   IK+  +     + +    +    D      P  +  +D 
Sbjct: 15143 DAITCRD--------DVEAPKIKVDVKFKDTVILKAGEAFRLEADVSGRPPPTMEWSKDG 15194

Query: 1778  AELQGL---------------------RPGSEYTVSVVALHDDMESQPLIGTQSTAIPAP 1816
              EL+G                      R    YT++  A +    ++ +   +    P P
Sbjct: 15195 KELEGTAKLEIKIADFSTNLVNKDSTRRDSGAYTLT--ATNPGGFAKHIFNVKVLDRPGP 15252

Query: 1817  TD--LKFTQVTPTSLSAQWTPP----NVQLTGYRVRVTPKEKTGPMKEINLAPD--SSSV 1868
              +  L  T+VT       W PP      ++  Y   +  K +T  +   N+A +   + +
Sbjct: 15253 PEGPLAVTEVTSEKCVLSWFPPLDDGGAKIDHY---IVQKRETSRLAWTNVASEVQVTKL 15309

Query: 1869  VVSGLMVATKY-----EVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITI 1923
              V+ L+   +Y      V+ Y + + L S P    V       PP+   VT  T+ ++ +
Sbjct: 15310 KVTKLLKGNEYIFRVMAVNKYGVGEPLESEPVL-AVNPYGPPDPPKNPEVTTITKDSMVV 15368

Query: 1924  SW----RTKTETITGFQVDAVPANGQTPIQRTIK--PDVRSYTITGLQPGTDYKIYLYTL 1977
              W          I  + V+     GQ  I+   K   D+R Y ++GL  G +Y+  +   
Sbjct: 15369 CWGHPDSDGGSEIINYIVERRDKAGQRWIKCNKKTLTDLR-YKVSGLTEGHEYEFRIMAE 15427

Query: 1978  NDNARSSP-------VVIDASTAIDAPSNLRFLATTPNSLLVSWQPP----RARITGYII 2026
             N    S+P          D       P N R L T+ +S+ ++W  P     + ITGY++
Sbjct: 15428 NAAGISAPSPTSPFYKACDTVFKPGPPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMV 15487

Query: 2027  KYEKPGSPPREVVPRPRP-GVTEATITGLEPGTEYTIYVIALKNNQKSEPLI 2077
             +   P     ++V  P     T  TITGL    EY I + A+ +    EP +
Sbjct: 15488 EIALPEEDEWQIVTPPAGLKATSYTITGLTENQEYKIRIYAMNSEGLGEPAL 15539



 Score =  123 bits (309), Expect = 2e-27
 Identities = 338/1634 (20%), Positives = 602/1634 (36%), Gaps = 228/1634 (13%)

Query: 613   EVFITETPSQPNSHP-----------IQWNAPQ---PSHISKYILRWRPKNSVGRWKEAT 658
             E ++   P  P   P           +QW  P     S I+ YI+  R     GRW +A+
Sbjct: 17208 ECYVARDPCDPPGTPEPIMVKRNEITLQWTKPVYDGGSMITGYIVEKRDLPD-GRWMKAS 17266

Query: 659   IPGHLNS-YTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTP 717
                 + + +T+ GL     YE ++I+    G         +  S ST      +T +   
Sbjct: 17267 FTNVIETQFTVSGLTEDQRYEFRVIAKNAAGA-------ISKPSDST----GPITAKDEV 17315

Query: 718   FSPLVATSESVTEITASSFVVSWVSASD-------TVSGFRVEYELSEEGD-EPQYLDLP 769
               P ++      +    +   ++   +D       T+   R + E+ E    E +  D  
Sbjct: 17316 ELPRISMDPKFRDTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFK 17375

Query: 770   STATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPT-VDQVDDTSIV 828
             +    V     + G +YI+    ++  G +S  ++      P  P  P  V  V      
Sbjct: 17376 ALLI-VKDAIRIDGGQYILRASNVA--GSKSFPVNVKVLDRPGPPEGPVQVTGVTSEKCS 17432

Query: 829   VRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITI---- 880
             + WS P     + I+ Y +    +   + T +      NS+ ++ L  G +Y   I    
Sbjct: 17433 LTWSPPLQDGGSDISHYVVEKRETSRLAWTVVASEVVTNSLKVTKLLEGNEYVFRIMAVN 17492

Query: 881   -YAVEENQESTPVVIQQETTGTPRSDTVPSP-RDLQFVEVTDVKVTIMWTPPES----AV 934
              Y V E  ES PV+++           +P P + L+   +    +T+ W  P+S     +
Sbjct: 17493 KYGVGEPLESAPVLMKNPFV-------LPGPPKSLEVTNIAKDSMTVCWNRPDSDGGSEI 17545

Query: 935   TGYRV---DVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTA 991
              GY V   D   +     + +R+   R     VTGL+    Y F+V A +     +P  A
Sbjct: 17546 IGYIVEKRDRSGIRWIKCNKRRITDLR---LRVTGLTEDHEYEFRVSAENAAGVGEPSPA 17602

Query: 992   -------QQTTKLDAPTNLQFVNETDSTVLVRWTPP----RAQITGYRLTVGLTRRGQPR 1040
                        K   PTN   V+ T +++ + W  P     ++I GY   V + +  +  
Sbjct: 17603 TVYYKACDPVFKPGPPTNAHIVDTTKNSITLAWGKPIYDGGSEILGY--VVEICKADEEE 17660

Query: 1041  QYNVGPS----VSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNT 1096
                V P     V+++ +  L    EY + + A+       +AT V  T++P   +     
Sbjct: 17661 WQIVTPQTGLRVTRFEISKLTEHQEYKIRVCALN-KVGLGEATSVPGTVKPEDKLEAPEL 17719

Query: 1097  EVTETT---IVITWTPAPRIGFKLGVRPS-------QGGEAPREVTSDSG----SIVVSG 1142
             ++       IV+    + RI      RP+       + GE   +V  + G     + +  
Sbjct: 17720 DLDSELRKGIVVRAGGSARIHIPFKGRPTPEITWSREEGEFTDKVQIEKGVNYTQLSIDN 17779

Query: 1143  LTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHL-EANPDTGVLTVSWERSTTP 1201
                     Y +++      + A +  KV+    PP NL + E   D+  L   WE    P
Sbjct: 17780 CDRNDAGKYILKLENSSGSKSAFVTVKVLDTPGPPQNLAVKEVRKDSAFLV--WE---PP 17834

Query: 1202  DITGYRITTTPTNGQQGNSLEEVVHAD----QSSCTFDNLSPGLEYNVSVYTVKDDKESV 1257
              I G          ++ ++ +   +      ++S   +NL+ G  Y   V    +    V
Sbjct: 17835 IIDGGAKVKNYVIDKRESTRKAYANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFGVGV 17894

Query: 1258  PIS--DTIIPEVPQLTD--LSFVDITDSSIGLRWTPLN---SSTIIGYRITVVAAGEGIP 1310
             P+   D +    P      ++  D++ +S  L W        S ++GY   V    +G  
Sbjct: 17895 PVETVDAVKAAEPPSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLGY--VVEMQPKGTE 17952

Query: 1311  IFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTT---------LTQQTAVPPP 1361
              +    +S V    VTGL  G +Y   V      G+S P           LT Q ++  P
Sbjct: 17953 KWSIVAESKVCNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKLP 18012

Query: 1362  TDLRFTNIGPD---TMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTN 1418
              +      G D    + V   P P+I   +++    P+K       +++  +  + VL +
Sbjct: 18013 FNTYSIQAGEDLKIEIPVIGRPRPNI---SWVKDGEPLK---QTTRVNVEETATSTVL-H 18065

Query: 1419  LLPGTE------YVVSVSSVYEQHESTPLRGRQKTGLDSPTG-IDFSDITANSFTVHWIA 1471
             +  G +       V + +S     E+  +   +K G   P G + F +++A+   + W  
Sbjct: 18066 IKEGNKDDFGKYTVTATNSAGTATENLSVIVLEKPG--PPVGPVRFDEVSADFVVISWEP 18123

Query: 1472  PRAT----ITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREE 1527
             P  T    I+ Y +    +  +          +R +I +T L  GTEY   I A N   +
Sbjct: 18124 PAYTGGCQISNYIVEKR-DTTTTTWHMVSATVARTTIKITKLKTGTEYQFRIFAENRYGK 18182

Query: 1528  SPLLIGQQSTVS------DVPRDLEVVAATPTSLLISWDAP----AVTVRYYRITYGETG 1577
             S  L  +   V         P    V + +   +L+ W  P       +  Y +   E  
Sbjct: 18183 SAPLDSKAVIVQYPFKEPGPPGTPFVTSISKDQMLVQWHEPVNDGGTKIIGYHLEQKEKN 18242

Query: 1578  GNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPS 1637
                 V+    P   +    +GL  G++Y   V A    G    S        R   D P 
Sbjct: 18243 SILWVKLNKTPIQDTKFKTTGLDEGLEYEFKVSAENIVGIGKPSKVSECFVARDPCDPPG 18302

Query: 1638  QMQVTDVQDNSISVKW----LPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGL 1693
             + +   +  N++++KW        S +TGY V           K       +TE T+ GL
Sbjct: 18303 RPEAIVITRNNVTLKWKKPAYDGGSKITGYIVEKKDLPDGRWMKASFTNVLETEFTVSGL 18362

Query: 1694  QPTVEYVVSVYAQNPSGE-SQPLVQT-AVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVS 1751
                  Y   V A+N +G  S+P   + A+T  D        ++D  +  +  +     V 
Sbjct: 18363 VEDQRYEFRVIARNAAGNFSEPSDSSGAITARD--------EIDAPNASLDPKYKDVIVV 18414

Query: 1752  RYRVTYSSPED----GIHELFPAPDGE--EDTAELQGLRPGSEYTVSVV--ALHDD---- 1799
                 T+    D     I ++  + DG+  E+TA    ++   + T  VV   +  D    
Sbjct: 18415 HAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQY 18474

Query: 1800  -MESQPLIGTQSTAI-------PAPTD--LKFTQVTPTSLSAQWTPPNVQLTGYRVR--V 1847
              ++   + GT+S  I       P P +  LK T VT       W PP +Q  G  +   +
Sbjct: 18475 ILKLSNVGGTKSIPITVKVLDRPGPPEGPLKVTGVTAEKCYLAWNPP-LQDGGANISHYI 18533

Query: 1848  TPKEKTGPMK--EINLAPDSSSVVVSGLMVATKY-----EVSVYALKDTLTSRPAQGVVT 1900
               K +T  +   +++    + +  V+ L+   +Y      V+ Y + + L S P      
Sbjct: 18534 IEKRETSRLSWTQVSTEVQALNYKVTKLLPGNEYIFRVMAVNKYGIGEPLESGPVT-ACN 18592

Query: 1901  TLENVSPPRRARVTDATETTITISWRTKTE----TITGFQVDAVPANG--QTPIQRTIKP 1954
               +   PP    V+  T+ ++ ++W    +     I G+ ++     G   T   +    
Sbjct: 18593 PYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDKEGVRWTKCNKKTLT 18652

Query: 1955  DVRSYTITGLQPGTDYKIYLYTLNDNARSSPV-------VIDASTAIDAPSNLRFLATTP 2007
             D+R   +TGL  G  Y+  +   N      P          DA      PSN +   T+ 
Sbjct: 18653 DLR-LRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRACDALYPPGPPSNPKVTDTSR 18711

Query: 2008  NSLLVSWQPP----RARITGYIIKYEKPGSPPREVVPRPRPGV--TEATITGLEPGTEYT 2061
             +S+ ++W  P     A + GY+++  K  +        P  G+   + T+T L+  TEY 
Sbjct: 18712 SSVSLAWSKPIYDGGAPVKGYVVEV-KEAAADEWTTCTPPTGLQGKQFTVTKLKENTEYN 18770

Query: 2062  IYVIALKNNQKSEP 2075
               + A+ +    EP
Sbjct: 18771 FRICAINSEGVGEP 18784



 Score =  123 bits (309), Expect = 2e-27
 Identities = 314/1502 (20%), Positives = 546/1502 (36%), Gaps = 190/1502 (12%)

Query: 619   TPSQPNSHPIQWNAP---QPSHISKYILRWRPKNSVGRWKEATIPGHLNS--YTIKGLKP 673
             T +  +S  + W+ P     + +  Y++  + + +   W   T P  L    +T+  LK 
Sbjct: 18707 TDTSRSSVSLAWSKPIYDGGAPVKGYVVEVK-EAAADEWTTCTPPTGLQGKQFTVTKLKE 18765

Query: 674   GVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITA 733
                Y  ++ +I   G  E        T   + V    +     P   L A    V  + A
Sbjct: 18766 NTEYNFRICAINSEGVGE------PATLPGSVVAQERIE---PPEIELDADLRKVVVLRA 18816

Query: 734   SSFVVSWVSASDTVSGFRVEYELSEEGDEP-----QYLDLPSTATSVNIPDLLPGRKYIV 788
             S+ +  +V    T+ G R E E+  E  E        +++ S+ T + I ++        
Sbjct: 18817 SATLRLFV----TIKG-RPEPEVKWEKAEGILTDRAQIEVTSSFTMLVIDNVTRFDSGRY 18871

Query: 789   NVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ----APITGYRIV 844
             N+   +  G ++  ++     +P AP + T+ +V   S+ + W  P     A IT Y + 
Sbjct: 18872 NLTLENNSGSKTAFVNVRVLDSPSAPVNLTIREVKKDSVTLSWEPPLIDGGAKITNYIVE 18931

Query: 845   YSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRS 904
                +   +   +    T  +  + +LQ G  Y   + A  E     P     ETT   + 
Sbjct: 18932 KRETTRKAYATITNNCTKTTFRIENLQEGCSYYFRVLASNEYGIGLPA----ETTEPVKV 18987

Query: 905   DTVPSPRD-LQFVEVTDVKVTIMWTPPES----AVTGYRVDVIPVNLPGEHGQRLPISRN 959
                P P   +  V+VT    TI W  PES     +TGY V++       E        + 
Sbjct: 18988 SEPPLPPGRVTLVDVTRNTATIKWEKPESDGGSKITGYVVEMQTKG--SEKWSTCTQVKT 19045

Query: 960   TFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWT- 1018
               A ++GL+ G  Y F+V AV+    S P       +L  P   + +    S  L   T 
Sbjct: 19046 LEATISGLTAGEEYVFRVAAVNEKGRSDP------RQLGVPVIARDIEIKPSVELPFHTF 19099

Query: 1019  --PPRAQIT-------GYRLTVGLTRRGQP----RQYNVGPSVSKYPLRNLQPASEYTVS 1065
                 R Q+          + TV   + GQ      + NV  S +   L +++ AS+  V 
Sbjct: 19100 NVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSL-SIKEASKEDVG 19158

Query: 1066  LVAIKGNQESPKATGVFTTL---QPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPS 1122
                +  +  +   T   T +   +PG   P    EV+  +I I+W P    G   G + S
Sbjct: 19159 TYELCVSNSAGSITVPITIIVLDRPGPPGPIRIDEVSCDSITISWNPPEYDG---GCQIS 19215

Query: 1123  QGGEAPREVTSDSGSIV----------VSGLTPGVEYVYTIQVL-RDGQ----ERDAPIV 1167
                   +E TS +  IV          +  LT G EY + +    R G+    E  A + 
Sbjct: 19216 NYIVEKKETTSTTWHIVSQAVARTSIKIVRLTTGSEYQFRVCAENRYGKSSYSESSAVVA 19275

Query: 1168  NKVVTPLSPP-TNLHLEANPDTGVLTVSWERSTTPD---ITGYRITTTPTNGQQGNSLEE 1223
                 +P  PP T   + A   T  + V+W+         + GY +     +    +   +
Sbjct: 19276 EYPFSPPGPPGTPKVVHATKST--MLVTWQVPVNDGGSRVIGYHLEYKERSSILWSKANK 19333

Query: 1224  VVHADQSSCTFDNLSPGLEYNVSVYT--------VKDDKESVPISDTIIPE-VPQLTDLS 1274
             ++ AD +      L  GL Y   VY              E VP  D   P   P++T+  
Sbjct: 19334 ILIAD-TQMKVSGLDEGLMYEYRVYAENIAGIGKCSKSCEPVPARDPCDPPGQPEVTN-- 19390

Query: 1275  FVDITDSSIGLRWTPLN---SSTIIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPG 1331
                IT  S+ L+W+  +    + I GY +      +G  +  ++ +    Y+ VT L   
Sbjct: 19391 ---ITRKSVSLKWSKPHYDGGAKITGYIVERRELPDGRWLKCNYTNIQETYFEVTELTED 19447

Query: 1332  IDYDISVI------TLINGGESAPTTLTQQTAVPPPT--DLRFTNI----GPDTMRVT-- 1377
               Y+  V       ++    ES    + +    PP    D++F ++      + +++   
Sbjct: 19448 QRYEFRVFARNAADSVSEPSESTGPIIVKDDVEPPRVMMDVKFRDVIVVKAGEVLKINAD 19507

Query: 1378  --WAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNL----LPGTEYVVSVSS 1431
                 P P I      +        E+ A   I  +DN  +LT          +YV+++ +
Sbjct: 19508 IAGRPLPVISWAKDGIEI------EERARTEIISTDNHTLLTVKDCIRRDTGQYVLTLKN 19561

Query: 1432  VYEQHE-STPLRGRQKTGLDSPTG-IDFSDITANSFTVHWIAPR----ATITGYRI-RHH 1484
             V      +   +   K G   P G ++ + +TA   ++ W  P+    A I  Y + +  
Sbjct: 19562 VAGTRSVAVNCKVLDKPG--PPAGPLEINGLTAEKCSLSWGRPQEDGGADIDYYIVEKRE 19619

Query: 1485  PEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGR------EESPLLIGQQSTV 1538
               H +    E  +     S  +T L  G EY+  +  +N        E   +      TV
Sbjct: 19620 TSHLAWTICEGEL--QMTSCKVTKLLKGNEYIFRVTGVNKYGVGEPLESVAIKALDPFTV 19677

Query: 1539  SDVPRDLEVVAATPTSLLISWDAP----AVTVRYYRITYGETGGNSPVQEFTVPGSKSTA 1594
                P  LE+ + T  S+ + W  P       +  Y I   E      V+    P      
Sbjct: 19678 PSPPTSLEITSVTKESMTLCWSRPESDGGSEISGYIIERREKNSLRWVRVNKKPVYDLRV 19737

Query: 1595  TISGLKPGVDYTITVYAVTGRGDS-PASSKPISINYRTEI---DKPSQMQVTDVQDNSIS 1650
               +GL+ G +Y   VYA    G S P+ + P+ I     +     PS+ ++ D    +I+
Sbjct: 19738 KSTGLREGCEYEYRVYAENAAGLSLPSETSPL-IRAEDPVFLPSPPSKPKIVDSGKTTIT 19796

Query: 1651  VKWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQ 1706
             + W+       +P+TGY V    K+     KT       TE TI GL    EYV  V + 
Sbjct: 19797 IAWVKPLFDGGAPITGYTVEYK-KSDDTDWKTSIQSLRGTEYTISGLTTGAEYVFRVKSV 19855

Query: 1707  NPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRY---------RVTY 1757
             N  G S P   +        +     D+D +  K          +            V +
Sbjct: 19856 NKVGASDPSDSSDPQIAKEREEEPLFDIDSEMRKTLIVKAGASFTMTVPFRGRPVPNVLW 19915

Query: 1758  SSPEDGIHELFPAPDGEEDTA---ELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIP 1814
             S P+  +         +  T+   E        +YT+++  +        ++    T  P
Sbjct: 19916 SKPDTDLRTRAYVDTTDSRTSLTIENANRNDSGKYTLTIQNVLSAASLTLVVKVLDTPGP 19975

Query: 1815  APTDLKFTQVTPTSLSAQWTPP----NVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVV 1870
              PT++    VT  S    W  P       +  Y +      K   +   N   +  S  V
Sbjct: 19976 -PTNITVQDVTKESAVLSWDVPENDGGAPVKNYHIEKREASKKAWVSVTNNC-NRLSYKV 20033

Query: 1871  SGLMVATKYEVSVYALKDTLTSRPA---QGVVTTLENVSPPRRARVTDATETTITISW-- 1925
             + L     Y   V    +     PA   +GV  T E  SPP +  VT  ++ +++++W  
Sbjct: 20034 TNLQEGAIYYFRVSGENEFGVGIPAETKEGVKIT-EKPSPPEKLGVTSISKDSVSLTWLK 20092

Query: 1926  --RTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARS 1983
                     I  + V+A+    +  ++  +      + ++GL+  ++Y   ++  N    S
Sbjct: 20093 PEHDGGSRIVHYVVEALEKGQKNWVKCAVAKSTH-HVVSGLRENSEYFFRVFAENQAGLS 20151

Query: 1984  SP 1985
              P
Sbjct: 20152 DP 20153



 Score =  122 bits (307), Expect = 3e-27
 Identities = 331/1598 (20%), Positives = 562/1598 (35%), Gaps = 189/1598 (11%)

Query: 624   NSHPIQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNS--YTIKGLKPGVVYE 678
             NS  + W  P+    S I +YIL  R K S  RW +      ++   + + GL  G  YE
Sbjct: 21861 NSITLTWARPESDGGSEIQQYILERREKKST-RWVKVISKRPISETRFKVTGLTEGNEYE 21919

Query: 679   GQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVV 738
               +++    G    +           PV          P  P V     VT+ + ++  +
Sbjct: 21920 FHVMAENAAGVGPASGIS-RLIKCREPVNP--------PGPPTVV---KVTDTSKTTVSL 21967

Query: 739   SW----VSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQIS 794
              W          + G+ +E   ++ GD  +        T   + DL  G +Y   V  I+
Sbjct: 21968 EWSKPVFDGGMEIIGYIIEMCKADLGDWHKVNAEACVKTRYTVTDLQAGEEYKFRVSAIN 22027

Query: 795   EDGEQSLILSTSQTTAPD--APPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGS 852
               G+      T    A D    P+  +D     + VVR          Y+   +P+   S
Sbjct: 22028 GAGKGDSCEVTGTIKAVDRLTAPELDIDANFKQTHVVRAGASIRLFIAYQGRPTPTAVWS 22087

Query: 853   STELNLPETANSVTLSDLQPGVQYNIT-------IYAVEENQESTPVVIQQETTGTPRSD 905
               + NL   A+  T          N            VE N  S  +    +   TP   
Sbjct: 22088 KPDSNLSLRADIHTTDSFSTLTVENCNRNDAGKYTLTVENNSGSKSITFTVKVLDTPGP- 22146

Query: 906   TVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPGEHGQRLPISRNTF 961
                 P  + F +VT    T+MW  P     + +  Y V+    +           +R  F
Sbjct: 22147 ----PGPITFKDVTRGSATLMWDAPLLDGGARIHHYVVEKREASRRSWQVISEKCTRQIF 22202

Query: 962   AEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQ----TTKLDAPTNLQFVNETDSTVLVRW 1017
              +V  L+ GV YYF+V AV+     +P    +    T +   P  L  V+ + S+ ++ W
Sbjct: 22203 -KVNDLAEGVPYYFRVSAVNEYGVGEPYEMPEPIVATEQPAPPRRLDVVDTSKSSAVLAW 22261

Query: 1018  TPP----RAQITGYRLTVGLTRRGQPRQYNVGPSVS-KYPLRNLQPASEY---------- 1062
               P     ++ITGY L   + ++G       G +    + +  L   +EY          
Sbjct: 22262 LKPDHDGGSRITGYLLE--MRQKGSDFWVEAGHTKQLTFTVERLVEKTEYEFRVKAKNDA 22319

Query: 1063  -------TVSLVAIKGNQESPKA--TGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRI 1113
                      S V IK  Q  P A  TG+   L    +  P+  +V      I+  PAP++
Sbjct: 22320 GYSEPREAFSSVIIKEPQIEPTADLTGITNQLITCKAGSPFTIDVP-----ISGRPAPKV 22374

Query: 1114  GFKL-GVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVT 1172
              +KL  +R  +        T D  ++ V     G    Y + +      +   +   V+ 
Sbjct: 22375 TWKLEEMRLKETDRVSITTTKDRTTLTVKDSMRGDSGRYFLTLENTAGVKTFSVTVVVIG 22434

Query: 1173  PLSPPTNLHLEANPDTGVLTVSW---ERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQ 1229
                P T     ++       +SW   +     +IT Y +    +       +   V   Q
Sbjct: 22435 RPGPVTGPIEVSSVSAESCVLSWGEPKDGGGTEITNYIVEKRESGTTAWQLVNSSVKRTQ 22494

Query: 1230  SSCTFDNLSPGLEYNVSV-----YTVKDDKESVPI---SDTIIPEVPQLTDLSFVDITDS 1281
                T  +L+  +EY+  V     + V    ES PI      + P  P  T      ++ +
Sbjct: 22495 IKVT--HLTKYMEYSFRVSSENRFGVSKPLESAPIIAEHPFVPPSAP--TRPEVYHVSAN 22550

Query: 1282  SIGLRWTPL---NSSTIIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISV 1338
             ++ +RW        S IIGY +        + + E+ V      Y VTGL  G++Y    
Sbjct: 22551 AMSIRWEEPYHDGGSKIIGYWVEKKERNTILWVKENKVPCLECNYKVTGLVEGLEYQFRT 22610

Query: 1339  ITLINGGES----APTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAPPP---SIDLTNFLV 1391
               L   G S    A   +  Q  V  P     T++   T+ + W+ P       +  +++
Sbjct: 22611 YALNAAGVSKASEASRPIMAQNPVDAPGRPEVTDVTRSTVSLIWSAPAYDGGSKVVGYII 22670

Query: 1392  RYSPVKNEEDVAELSIS---PSDNAVVLTNLLPGTEYVVSVSS------VYEQHEST-PL 1441
                PV    D   L  +    SDN   +T L  G  Y   V +      + +  EST P+
Sbjct: 22671 ERKPVSEVGDGRWLKCNYTIVSDNFFTVTALSEGDTYEFRVLAKNAAGVISKGSESTGPV 22730

Query: 1442  RGRQ-----KTGLDSPTGIDFSDITANSFTVHWIA----PRATITGYRIRHHPEHFSGRP 1492
               R      K  LD+    D   I A S  V   A    P   I   +     +      
Sbjct: 22731 TCRDEYAPPKAELDARLHGDLVTIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVS 22790

Query: 1493  REDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVP---RDLEVVA 1549
              +     +   I   + +   +Y +++   +G +   +++     V D P     L V  
Sbjct: 22791 LQYTGKRATAVIKFCDRSDSGKYTLTVKNASGTKAVSVMV----KVLDSPGPCGKLTVSR 22846

Query: 1550  ATPTSLLISWDAP----AVTVRYYRITYGETGGNSPVQEFTVPGSKSTAT--ISGLKPGV 1603
              T     ++W  P       + +Y +   ET   S +    V G   T +  ++ L    
Sbjct: 22847 VTQEKCTLAWSLPQEDGGAEITHYIVERRET---SRLNWVIVEGECPTLSYVVTRLIKNN 22903

Query: 1604  DYTITVYAVTGRGDS-PASSKPI-SINYRTEIDKPSQMQVTDVQDNSISVKWLPSSS--- 1658
             +Y   V AV   G   P  S+PI + N  T    P   +        I ++W    S   
Sbjct: 22904 EYIFRVRAVNKYGPGVPVESEPIVARNSFTIPSPPGIPEEVGTGKEHIIIQWTKPESDGG 22963

Query: 1659  -PVTGYRVTTTPKNGPGPTK-TKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLV 1716
               ++ Y V    K     T+  K      T + +  L    +Y   V A N +G S+P  
Sbjct: 22964 NEISNYLVDKREKKSLRWTRVNKDYVVYDTRLKVTSLMEGCDYQFRVTAVNAAGNSEPSE 23023

Query: 1717  QTAVTNIDR-------PKGLAFTDVDVDSIKIAWESPQGQVSRYRVTY-----SSPEDGI 1764
              +   +          P      D    SI +AW  P        V Y         D  
Sbjct: 23024 ASNFISCREPSYTPGPPSAPRVVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDTDQW 23083

Query: 1765  HELFPAPDGEEDTAELQGLRPGSEYTVSVVALH---------DDMESQPLIGTQSTAIPA 1815
             + +            +  L+ G +Y+  V A++            E +P+   +   +  
Sbjct: 23084 YRVHTNATIRNTEFTVPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEIPDLEL 23143

Query: 1816  PTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTG---PMKEINLAPDSSSVVVSG 1872
               DLK T       S +     V ++G    V    K G     + I    +S S+++  
Sbjct: 23144 ADDLKKTVTIRAGASLRLM---VSVSGRPPPVITWSKQGIDLASRAIIDTTESYSLLI-- 23198

Query: 1873  LMVATKYEVSVYALKDTLTS--RPAQGVVTTLENVSPPRRARVTDATETTITISWRTKT- 1929
             +    +Y+   Y ++    S  + A  +V   +   P    +V + +  ++TI+W   T 
Sbjct: 23199 VDKVNRYDAGKYTIEAENQSGKKSATVLVKVYDTPGPCPSVKVKEVSRDSVTITWEIPTI 23258

Query: 1930  ---ETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKI-----YLYTLNDNA 1981
                  +  + V+   A  +     T K     Y I+GL  GT Y        +Y + +  
Sbjct: 23259 DGGAPVNNYIVEKREAAMRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYGIGEPC 23318

Query: 1982  RSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPP----RARITGYIIKYEKPGSPPRE 2037
              +S  V+ +   +  P+ L  +  T +++ ++W+ P     +R+TGY+++  K G+    
Sbjct: 23319 ETSDAVLVSEVPL-VPAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGTERWM 23377

Query: 2038  VVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEP 2075
              V   +P V E T+T L  G +Y   + A      SEP
Sbjct: 23378 KVVTLKPTVLEHTVTSLNEGEQYLFRIRAQNEKGVSEP 23415



 Score =  120 bits (301), Expect = 2e-26
 Identities = 286/1368 (20%), Positives = 511/1368 (37%), Gaps = 206/1368 (15%)

Query: 866   TLSDLQPGVQYNITIYAVEENQEST-PVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVT 924
             T++ L  G +Y   + A  EN+  T P    +      + D    P   +  +V+  ++T
Sbjct: 12051 TVTRLIEGNEYIFRVRA--ENKIGTGPPTESKPVIAKTKYDKPGRPDPPEVTKVSKEEMT 12108

Query: 925   IMWTPPE----SAVTGYRVDVIPVNLPGEHGQR-LPISRNTFAE----VTGLSPGVTYYF 975
             ++W PPE     ++TGY ++        +H  R +P++++   E    V  L P   Y F
Sbjct: 12109 VVWNPPEYDGGKSITGYFLEK-----KEKHSTRWVPVNKSAIPERRMKVQNLLPDHEYQF 12163

Query: 976   KVFAVSH------GRESKPLTAQQTTKLDAP-TNLQFVNETDSTVLVRWTPP----RAQI 1024
             +V A +          S+P+ A+   +   P TN + V+ T  ++ + W  P     A I
Sbjct: 12164 RVKAENEIGIGEPSLPSRPVVAKDPIEPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAPI 12223

Query: 1025  TGY------RLTVGLTRRGQPRQYNVGPSVSK-YPLRNLQPASEYTVSL-----VAIKGN 1072
              GY      ++       G  R       V K + + +L    EY   +     V I   
Sbjct: 12224 IGYVVEMRPKIADASPDEGWKRCNAAAQLVRKEFTVTSLDENQEYEFRVCAQNQVGIGRP 12283

Query: 1073  QESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWT-------------PAPRIGFKLGV 1119
              E  +A      L+P    P  + + +   +VI                PAP++ ++   
Sbjct: 12284 AELKEAIKPKEILEP----PEIDLDASMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVG 12339

Query: 1120  RPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTN 1179
               +   +   ++      +V+   T      Y++ ++    E+   +  +V+    P ++
Sbjct: 12340 IDNVVRKGQVDLVDTMAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFVNVRVLDTPGPVSD 12399

Query: 1180  LHLEANPDTGVLTVSW---ERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDN 1236
             L +     T    VSW   E      +T Y +     + +  +++   V   ++S    N
Sbjct: 12400 LKVSDVTKTSC-HVSWAPPENDGGSQVTHYIVEKREADRKTWSTVTPEVK--KTSFHVTN 12456

Query: 1237  LSPGLEYNVSVYTVKDDKESVPI--------SDTII-PEVPQLTDLSFVDITDSSIGLRW 1287
             L PG EY   V  V +    VP         SD +  P+ P+   L   ++T +S  L W
Sbjct: 12457 LVPGNEYYFRVTAVNEYGPGVPTDVPKPVLASDPLSEPDPPR--KLEVTEMTKNSATLAW 12514

Query: 1288  TPL---NSSTIIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLING 1344
              P      + I GY  +     +    + ++         VTGL+ G  Y   V      
Sbjct: 12515 LPPLRDGGAKIDGYITSYREEEQPADRWTEYSVVKDLSLVVTGLKEGKKYKFRVAARNAV 12574

Query: 1345  GESAPTTL-----TQQTAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVK-- 1397
             G S P         ++  +PP        + P+ + +       I+   +   +   K  
Sbjct: 12575 GVSLPREAEGVYEAKEQLLPPKI------LMPEQITIKAGKKLRIEAHVYGKPHPTCKWK 12628

Query: 1398  -NEEDV---AELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSP- 1452
               E++V   + L++  +D++ +L       +     S   E    T  +  +   +D+P 
Sbjct: 12629 KGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPG 12688

Query: 1453  ---TGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPH----SRNSIT 1505
                   D SDI A++ ++ W  P     G  I ++        R D V      ++ S  
Sbjct: 12689 PPQPPFDISDIDADACSLSWHIPLED-GGSNITNYIVEKCDVSRGDWVTALASVTKTSCR 12747

Query: 1506  LTNLTPGTEYVVSIVALN--GREE---SPLLIGQ-QSTVSDVPRDLEVVAATPTSLLISW 1559
             +  L PG EY+  + A N  G  E   SP ++ Q    V   P++  V       + ++W
Sbjct: 12748 VGKLIPGQEYIFRVRAENRFGISEPLTSPKMVAQFPFGVPSEPKNARVTKVNKDCIFVAW 12807

Query: 1560  DAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATI----------------SGLKPGV 1603
             D P            ++ G SP+  + +   +  + +                +GL  G+
Sbjct: 12808 DRP------------DSDGGSPIIGYLIERKERNSLLWVKANDTLVRSTEYPCAGLVEGL 12855

Query: 1604  DYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWL----PSSSP 1659
             +Y+  +YA+   G SP S     +  R  +D P + +V DV  +++S+ W        S 
Sbjct: 12856 EYSFRIYALNKAGSSPPSKPTEYVTARMPVDPPGKPEVIDVTKSTVSLIWARPKHDGGSK 12915

Query: 1660  VTGYRVTTTPKNGPGPTKTKTAGPD--QTEMTIEGLQPTVEYVVSVYAQN------PSGE 1711
             + GY V      G    +  TA     Q E T  GL+   +Y     A+       PS  
Sbjct: 12916 IIGYFVEACKLPGDKWVRCNTAPHQIPQEEYTATGLEEKAQYQFRAIARTAVNISPPSEP 12975

Query: 1712  SQP---LVQTAVTNIDRPKGL-------AFTDVDVDSIKIAWESPQGQVS-RYRVTYSSP 1760
             S P   L +     ID    +       A T+V +D+    +  P   VS +   T   P
Sbjct: 12976 SDPVTILAENVPPRIDLSVAMKSLLTVKAGTNVCLDA--TVFGKPMPTVSWKKDGTLLKP 13033

Query: 1761  EDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPA-PTDL 1819
              +GI     A      T EL  +        ++ A +        I  +    P  P  +
Sbjct: 13034 AEGIK---MAMQRNLCTLELFSVNRKDSGDYTITAENSSGSKSATIKLKVLDKPGPPASV 13090

Query: 1820  KFTQVTPTSLSAQWTPP----NVQLTGYRVRVTPKEKTGP-MKEINLAPDSSSVVVSGLM 1874
             K  ++        W PP      ++T Y   V  +E + P   +++     +S  V  L+
Sbjct: 13091 KINKMYSDRAMLSWEPPLEDGGSEITNY--IVDKRETSRPNWAQVSATVPITSCSVEKLI 13148

Query: 1875  VATKYEVSV-----YALKDTLTSRPAQGVVTTLENVSPPRRAR---VTDATETTITISWR 1926
                +Y+  +     Y + D + + PA           PP R     +++ T+  +T+SW+
Sbjct: 13149 EGHEYQFRICAENKYGVGDPVFTEPA----IAKNPYDPPGRCDPPVISNITKDHMTVSWK 13204

Query: 1927  TKTE----TITGFQVDAVPANGQTPIQRTIKPDV-RSYTITGLQPGTDYKIYLYTLNDNA 1981
                +     ITG+ ++          +   KP + R+   TGLQ GT+Y+  +  +N   
Sbjct: 13205 PPADDGGSPITGYLLEKRETQAVNWTKVNRKPIIERTLKATGLQEGTEYEFRVTAINKAG 13264

Query: 1982  RSSPVVIDASTAIDA---------PSNLRFLATTPNSLLVSWQPPR----ARITGYIIKY 2028
                P   DAS A  A         P+  +   TT +S+ +SW  P     + I GY+++ 
Sbjct: 13265 PGKP--SDASKAAYARDPQYPPGPPAFPKVYDTTRSSVSLSWGKPAYDGGSPIIGYLVEV 13322

Query: 2029  EKPGSPPREVVPRPRP-GVTEATITGLEPGTEYTIYVIALKNNQKSEP 2075
             ++  S        P+    T   +TGL   T+Y   V A+     S+P
Sbjct: 13323 KRADSDNWVRCNLPQNLQKTRFEVTGLMEDTQYQFRVYAVNKIGYSDP 13370



 Score =  120 bits (301), Expect = 2e-26
 Identities = 304/1512 (20%), Positives = 534/1512 (35%), Gaps = 204/1512 (13%)

Query: 718   FSPLVATSESVTEITASSFVVSW----VSASDTVSGFRVEYELSEEGDEPQYLDLPSTA- 772
             F P   T+  + + T +S  ++W          + G+ VE  + +  +E   +  P T  
Sbjct: 17613 FKPGPPTNAHIVDTTKNSITLAWGKPIYDGGSEILGYVVE--ICKADEEEWQIVTPQTGL 17670

Query: 773   --TSVNIPDLLPGRKYIVNVYQISEDG--EQSLILSTSQTTAPDAPPDPTVDQVDDTSIV 828
               T   I  L   ++Y + V  +++ G  E + +  T +       P+  +D      IV
Sbjct: 17671 RVTRFEISKLTEHQEYKIRVCALNKVGLGEATSVPGTVKPEDKLEAPELDLDSELRKGIV 17730

Query: 829   VRW---SRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYN-ITIYAVE 884
             VR    +R   P  G     +P +  S  E    +         ++ GV Y  ++I   +
Sbjct: 17731 VRAGGSARIHIPFKGRP---TPEITWSREEGEFTDKVQ------IEKGVNYTQLSIDNCD 17781

Query: 885   ENQESTPVVIQQETTGTPRS-------DTVPSPRDLQFVEVTDVKVTIMWTPP----ESA 933
              N     ++  + ++G+  +       DT   P++L   EV      ++W PP     + 
Sbjct: 17782 RNDAGKYILKLENSSGSKSAFVTVKVLDTPGPPQNLAVKEVRKDSAFLVWEPPIIDGGAK 17841

Query: 934   VTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQ 993
             V  Y +D                S+ +F +V  L+ G  YYF+V A +      P+    
Sbjct: 17842 VKNYVIDKRESTRKAYANVSSKCSKTSF-KVENLTEGAIYYFRVMAENEFGVGVPVETVD 17900

Query: 994   TTKLDAPTN------LQFVNETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYN 1043
               K   P +      L  V++T ++++  W  P     +++ GY   V +  +G  +   
Sbjct: 17901 AVKAAEPPSPPGKVTLTDVSQTSASLM--WEKPEHDGGSRVLGY--VVEMQPKGTEKWSI 17956

Query: 1044  VGPS-VSKYPLRNLQPASEYTVSLVAIKGNQES-PKATGVFT-----TLQPGSSIPPYNT 1096
             V  S V    +  L    EY   + A     +S P+  GV       T+QP   +P +NT
Sbjct: 17957 VAESKVCNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKLP-FNT 18015

Query: 1097  ------EVTETTIVITWTPAPRIGF-KLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEY 1149
                   E  +  I +   P P I + K G    Q      E T+ S  + +         
Sbjct: 18016 YSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFG 18075

Query: 1150  VYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTP---DITGY 1206
              YT+            +   V+    PP             + +SWE         I+ Y
Sbjct: 18076 KYTVTATNSAGTATENLSVIVLEKPGPPVGPVRFDEVSADFVVISWEPPAYTGGCQISNY 18135

Query: 1207  RITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTII-- 1264
              +    T     + +   V   +++     L  G EY   ++      +S P+    +  
Sbjct: 18136 IVEKRDTTTTTWHMVSATVA--RTTIKITKLKTGTEYQFRIFAENRYGKSAPLDSKAVIV 18193

Query: 1265  ---------PEVPQLTDLSFVDITDSSIGLRW-TPLNS--STIIGYRITVVAAGEGIPIF 1312
                      P  P +T +S        + ++W  P+N   + IIGY +        + + 
Sbjct: 18194 QYPFKEPGPPGTPFVTSIS-----KDQMLVQWHEPVNDGGTKIIGYHLEQKEKNSILWVK 18248

Query: 1313  EDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQ----QTAVPPPTDLRFTN 1368
              +        +  TGL+ G++Y+  V      G   P+ +++    +    PP       
Sbjct: 18249 LNKTPIQDTKFKTTGLDEGLEYEFKVSAENIVGIGKPSKVSECFVARDPCDPPGRPEAIV 18308

Query: 1369  IGPDTMRVTWAPPP---SIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEY 1425
             I  + + + W  P       +T ++V     K+  D   +  S        TN+L  TE+
Sbjct: 18309 ITRNNVTLKWKKPAYDGGSKITGYIVEK---KDLPDGRWMKAS-------FTNVLE-TEF 18357

Query: 1426  VVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITG-YR---I 1481
              VS   V +Q     +  R   G  S        ITA        AP A++   Y+   +
Sbjct: 18358 TVS-GLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARD---EIDAPNASLDPKYKDVIV 18413

Query: 1482  RHHPEHF------SGRPREDRV--------------PHSRNSITLTNL-------TPGTE 1514
              H  E F       G+P  D V                 +++I  T L       T G +
Sbjct: 18414 VHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQ 18473

Query: 1515  YVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAP----AVTVRYYR 1570
             Y++ +  + G +  P+ +            L+V   T     ++W+ P       + +Y 
Sbjct: 18474 YILKLSNVGGTKSIPITVKVLDRPGPPEGPLKVTGVTAEKCYLAWNPPLQDGGANISHYI 18533

Query: 1571  ITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRG-DSPASSKPISI-N 1628
             I   ET   S  Q  T   + +   ++ L PG +Y   V AV   G   P  S P++  N
Sbjct: 18534 IEKRETSRLSWTQVSTEVQALNYK-VTKLLPGNEYIFRVMAVNKYGIGEPLESGPVTACN 18592

Query: 1629  YRTEIDKPSQMQVTDVQDNSISVKWL----PSSSPVTGYRVTTTPKNGPGPTKTKTAGPD 1684
                    PS  +V+ +  +S+ V W        + + GY +    K G   TK       
Sbjct: 18593 PYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDKEGVRWTKCNKKTLT 18652

Query: 1685  QTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQT-------AVTNIDRPKGLAFTDVDVD 1737
                + + GL     Y   V A+N +G  +P   +       A+     P     TD    
Sbjct: 18653 DLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRACDALYPPGPPSNPKVTDTSRS 18712

Query: 1738  SIKIAWESP----QGQVSRYRVTYSSPEDGIHELFPAPDGEEDTA-ELQGLRPGSEYTVS 1792
             S+ +AW  P       V  Y V               P G +     +  L+  +EY   
Sbjct: 18713 SVSLAWSKPIYDGGAPVKGYVVEVKEAAADEWTTCTPPTGLQGKQFTVTKLKENTEYNFR 18772

Query: 1793  VVALHDDMESQPL-----IGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRV 1847
             + A++ +   +P      +  Q    P   +L         L A  T         R+ V
Sbjct: 18773 ICAINSEGVGEPATLPGSVVAQERIEPPEIELDADLRKVVVLRASAT--------LRLFV 18824

Query: 1848  TPKEKTGPM----KEINLAPDSSSVVVSGLMV------ATKYEVSVY--ALKDTLTSRPA 1895
             T K +  P     K   +  D + + V+           T+++   Y   L++   S+ A
Sbjct: 18825 TIKGRPEPEVKWEKAEGILTDRAQIEVTSSFTMLVIDNVTRFDSGRYNLTLENNSGSKTA 18884

Query: 1896  QGVVTTLENVSPPRRARVTDATETTITISWRTKT----ETITGFQVDAVPANGQTPIQRT 1951
                V  L++ S P    + +  + ++T+SW          IT + V+      +     T
Sbjct: 18885 FVNVRVLDSPSAPVNLTIREVKKDSVTLSWEPPLIDGGAKITNYIVEKRETTRKAYATIT 18944

Query: 1952  IKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAP----SNLRFLATTP 2007
                   ++ I  LQ G  Y   +   N+     P        +  P      +  +  T 
Sbjct: 18945 NNCTKTTFRIENLQEGCSYYFRVLASNEYGIGLPAETTEPVKVSEPPLPPGRVTLVDVTR 19004

Query: 2008  NSLLVSWQPPRA----RITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIY 2063
             N+  + W+ P +    +ITGY+++ +  GS       + +    EATI+GL  G EY   
Sbjct: 19005 NTATIKWEKPESDGGSKITGYVVEMQTKGSEKWSTCTQVK--TLEATISGLTAGEEYVFR 19062

Query: 2064  VIALKNNQKSEP 2075
             V A+    +S+P
Sbjct: 19063 VAAVNEKGRSDP 19074



 Score =  119 bits (298), Expect = 4e-26
 Identities = 329/1550 (21%), Positives = 553/1550 (35%), Gaps = 222/1550 (14%)

Query: 601   PLQTYPSSSGPVEVFITETPSQPN-------SHPIQWNAPQ---PSHISKYILRWRPKNS 650
             P +T P       VF+   PS+P        +  I W  P     + I+ Y + ++  + 
Sbjct: 19763 PSETSPLIRAEDPVFLPSPPSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEYKKSDD 19822

Query: 651   VGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNT 710
                WK +        YTI GL  G  Y  ++ S+ + G  +        + +S P  +  
Sbjct: 19823 TD-WKTSIQSLRGTEYTISGLTTGAEYVFRVKSVNKVGASD-------PSDSSDPQIAKE 19874

Query: 711   VTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVS--GFRVEYELSEEGDEP----Q 764
                E     PL       +E+  +  V +  S + TV   G  V   L  + D       
Sbjct: 19875 REEE-----PLFDID---SEMRKTLIVKAGASFTMTVPFRGRPVPNVLWSKPDTDLRTRA 19926

Query: 765   YLDLPSTATSVNIPDLL--PGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQV 822
             Y+D   + TS+ I +       KY + +  +      +L++    T  P  P + TV  V
Sbjct: 19927 YVDTTDSRTSLTIENANRNDSGKYTLTIQNVLSAASLTLVVKVLDTPGP--PTNITVQDV 19984

Query: 823   DDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNI 878
                S V+ W  P+    AP+  Y I    + + +   +       S  +++LQ G  Y  
Sbjct: 19985 TKESAVLSWDVPENDGGAPVKNYHIEKREASKKAWVSVTNNCNRLSYKVTNLQEGAIYYF 20044

Query: 879   TIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAV 934
              +    E     P   ++   G   ++    P  L    ++   V++ W  PE    S +
Sbjct: 20045 RVSGENEFGVGIPAETKE---GVKITEKPSPPEKLGVTSISKDSVSLTWLKPEHDGGSRI 20101

Query: 935   TGYRVDVIPVNLPGEHGQR----LPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKP-- 988
               Y V+ +      E GQ+      ++++T   V+GL     Y+F+VFA +    S P  
Sbjct: 20102 VHYVVEAL------EKGQKNWVKCAVAKSTHHVVSGLRENSEYFFRVFAENQAGLSDPRE 20155

Query: 989   -LTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPS 1047
              L      +   P  +   N    TV VR         G  L V +   G+P    V  S
Sbjct: 20156 LLLPVLIKEQLEPPEIDMKNFPSHTVYVR--------AGSNLKVDIPISGKPLP-KVTLS 20206

Query: 1048  VSKYPLR-NLQPASEYTV---------SLVAIKGNQESPKATGVFTTL---------QPG 1088
                 PL+  ++  +E T          S+ A  G  E   A    TT          +PG
Sbjct: 20207 RDGVPLKATMRFNTEITAENLTINLKESVTADAGRYEITAANSSGTTKAFINIVVLDRPG 20266

Query: 1089  SSI-PPYNTEVTETTIVITWTPAPRIG-------FKLGVRPSQGGEAPREVTSDSGSIVV 1140
                 P   +++TE ++ + W P    G         L    S         T     + V
Sbjct: 20267 PPTGPVVISDITEESVTLKWEPPKYDGGSQVTNYILLKRETSTAVWTEVSATVARTMMKV 20326

Query: 1141  SGLTPGVEYVYTIQV-----LRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSW 1195
               LT G EY + I+      + D  +     V    T   PP+   +  N     +TV W
Sbjct: 20327 MKLTTGEEYQFRIKAENRFGISDHIDSACVTVKLPYTTPGPPSTPWV-TNVTRESITVGW 20385

Query: 1196  ERSTT---PDITGYRITTTPTNG---QQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYT 1249
                 +     + GY +     N    Q+ N L  V+       T   +S GL Y   VY 
Sbjct: 20386 HEPVSNGGSAVVGYHLEMKDRNSILWQKANKL--VIRTTHFKVT--TISAGLIYEFRVYA 20441

Query: 1250  V------KDDKESVPISDTIIPEVPQLTDLSFVDITDSSIGLRWTPL---NSSTIIGYRI 1300
                    K    S P+      E P+  ++   DI+ +S+ L W        S I GY +
Sbjct: 20442 ENAAGVGKPSHPSEPVLAIDACEPPR--NVRITDISKNSVSLSWQQPAFDGGSKITGYIV 20499

Query: 1301  TVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISV------------------ITLI 1342
                   +G      F + +   + ++GL     Y+  V                  IT I
Sbjct: 20500 ERRDLPDGRWTKASFTNVTETQFIISGLTQNSQYEFRVFARNAVGSISNPSEVVGPITCI 20559

Query: 1343  N--GGE--SAPTTLTQQTAVPPPTD--LRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPV 1396
             +  GG     P   T+       T   LR    G     + W        TN LV    V
Sbjct: 20560 DSYGGPVIDLPLEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALV---CV 20616

Query: 1397  KNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTG-I 1455
             +N  D+A + I  +D        L    Y + + +      +T +R +       P G I
Sbjct: 20617 ENTTDLASILIKDADR-------LNSGCYELKLRNAMGSASAT-IRVQILDKPGPPGGPI 20668

Query: 1456  DFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNS-------ITLTN 1508
             +F  +TA   T+ W  P A   G +I H   +   +    RV  S  S       IT T 
Sbjct: 20669 EFKTVTAEKITLLW-RPPADDGGAKITH---YIVEKRETSRVVWSMVSEHLEECIITTTK 20724

Query: 1509  LTPGTEYVVSIVALNGRE-----ESPLLIGQQSTVSDVPRDL-EVVAATPTSLLISWDAP 1562
             +  G EY+  + A+N        ES  ++ + + V+  P  + EV   T  S+ + W  P
Sbjct: 20725 IIKGNEYIFRVRAVNKYGIGEPLESDSVVAKNAFVTPGPPGIPEVTKITKNSMTVVWSRP 20784

Query: 1563  A------VTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRG 1616
                    ++  +      ++ G   V + T+  ++   T  GL    DY   V AV   G
Sbjct: 20785 IADGGSDISGYFLEKRDKKSLGWFKVLKETIRDTRQKVT--GLTENSDYQYRVCAVNAAG 20842

Query: 1617  DSPASSKPISINYRTEID---KPSQMQVTDVQDNSISVKW----LPSSSPVTGYRVTTTP 1669
               P S           ID    P+++++ D   +SI++ W        S VTGY V    
Sbjct: 20843 QGPFSEPSEFYKAADPIDPPGPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVVEIRQ 20902

Query: 1670  KNGPGPTKTKTAGPDQ-TEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKG 1728
                   T   T G  + TE  +  L+P V Y   V A N +G+ +P+       +     
Sbjct: 20903 GEEEEWTTVSTKGEVRTTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMN--EPVQAKDI 20960

Query: 1729  LAFTDVDVD-SIKIAWESPQGQVSRYRVTYSS--PEDGIHELFPAPDGEEDTAELQGLRP 1785
             L   ++D+D +++ +  +  G+  +  + +    P            G +    ++    
Sbjct: 20961 LEAPEIDLDVALRTSVIAKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYSIENTDS 21020

Query: 1786  GSEYTVSVVALHDDME---------SQPLIGTQSTAI----PAPTDLKFTQVTPTSLSAQ 1832
              S  T+  V  +D  +          +P   T S  +     A   L+   V+  +++  
Sbjct: 21021 SSLLTIPQVTRNDTGKYILTIENGVGEPKSSTVSVKVLDTPAACQKLQVKHVSRGTVTLL 21080

Query: 1833  WTPPNVQLTGYRVRVTPKEKTGPMKEINLAP---DSSSVVVSGLMVATKYEVSVYALKDT 1889
             W PP +      +    +++    +  ++      S+S  +  L   T +   V A  + 
Sbjct: 21081 WDPPLIDGGSPIINYVIEKRDATKRTWSVVSHKCSSTSFKLIDLSEKTPFFFRVLAENEI 21140

Query: 1890  LTSRPAQGV--VTTLENVSPPRRARVTDATETTITISWRTKTE-----TITGFQVDAVPA 1942
                 P +    V   E  +P R   + D+T+T++ +SW TK +      IT + V+    
Sbjct: 21141 GIGEPCETTEPVKAAEVPAPIRDLSMKDSTKTSVILSW-TKPDFDGGSVITEYVVERKGK 21199

Query: 1943  NGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDAST 1992
               QT     I        ++ L+  +  +  ++  N+   S PV I   T
Sbjct: 21200 GEQTWSHAGISKTC-EIEVSQLKEQSVLEFRVFAKNEKGLSDPVTIGPIT 21248



 Score =  118 bits (296), Expect = 6e-26
 Identities = 330/1625 (20%), Positives = 588/1625 (36%), Gaps = 230/1625 (14%)

Query: 611   PVEVFITETPSQPNSHPIQWNAP---QPSHISKYILRWRPKNSVGRWKEATIPGHLNSYT 667
             PV V + E     +S  + W  P     S I  Y+++ R       W   T      S+ 
Sbjct: 13485 PVNVTVKEISK--DSAYVTWEPPIIDGGSPIINYVVQKRDAERKS-WSTVTTECSKTSFR 13541

Query: 668   IKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSES 727
             +  L+ G  Y  ++ +  +YG  +               T + V    TP  P+V     
Sbjct: 13542 VANLEEGKSYFFRVFAENEYGIGDPGE------------TRDAVKASQTP-GPVVDLK-- 13586

Query: 728   VTEITASSFVVSWVS----ASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPG 783
             V  ++ SS  + W          + G+ V++ L+EE    + +   S +   +  DL  G
Sbjct: 13587 VRSVSKSSCSIGWKKPHSDGGSRIIGYVVDF-LTEENKWQRVMK--SLSLQYSAKDLTEG 13643

Query: 784   RKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWS---RPQAPITG 840
             ++Y   V   +E+GE +    T         PD  +  + D   + + +   R + PI G
Sbjct: 13644 KEYTFRVSAENENGEGTPSEITVVARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPIKG 13703

Query: 841   YRIVYSPSVE--------GSSTELNLPETANSVTLS--DLQPGV--QYNITIYAVEENQE 888
                  +PSV          + T +++  +A + TL   D Q     +Y IT+  V   +E
Sbjct: 13704 KP---APSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKE 13760

Query: 889   STPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPV 944
              T   I  +  G P   T P    ++F EVT   +T+ W PP+    S +T Y ++    
Sbjct: 13761 GT---ISIKVVGKPGIPTGP----IKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRD- 13812

Query: 945   NLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKV-----FAVSHGRESKPLTAQQTTKL-D 998
             ++  +        + T   VT L  G+ Y F+V     + V  G +S+P+ A+    + D
Sbjct: 13813 SVNNKWVTCASAVQKTTFRVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVPD 13872

Query: 999   APTNLQFVNETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGP-SVSKYPL 1053
             AP     V+    +V + WT P+    + ITGY L          ++ N  P  +  + +
Sbjct: 13873 APPPPNIVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTPIRMRDFKV 13932

Query: 1054  RNLQPASEYTVSLVAI------KGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITW 1107
               L    EY   ++AI      K +  S     +     PG    P    +T  ++ + W
Sbjct: 13933 TGLTEGLEYEFRVMAINLAGVGKPSLPSEPVVALDPIDPPGK---PEVINITRNSVTLIW 13989

Query: 1108  T-PAPRIGFKL-------GVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDG 1159
             T P    G KL          PS+       V     +  V+ L  G +Y + I+     
Sbjct: 13990 TEPKYDGGHKLTGYIVEKRDLPSKSWMKANHVNVPECAFTVTDLVEGGKYEFRIRAKNTA 14049

Query: 1160  QERDAPIVN----------KVVTPLSPPT---NLHLEANPDTGVLTV-----------SW 1195
                 AP  +          +  T +  PT    L ++A  DT VL             SW
Sbjct: 14050 GAISAPSESTETIICKDEYEAPTIVLDPTIKDGLTIKAG-DTIVLNAISILGKPLPKSSW 14108

Query: 1196  ERS----TTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVK 1251
              ++       DIT  +IT+TPT+     +++     D    T    +P        +  K
Sbjct: 14109 SKAGKDIRPSDIT--QITSTPTSSML--TIKYATRKDAGEYTITATNP--------FGTK 14156

Query: 1252  DDKESVPISDTIIPEVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGEGIPI 1311
              +   V + D  +P  P   ++S  +++     L WTP         +  ++   E   +
Sbjct: 14157 VEHVKVTVLD--VPGPPGPVEIS--NVSAEKATLTWTPPLEDGGSPIKSYILEKRETSRL 14212

Query: 1312  FEDFVDSSVG--YYTVTGLEPGIDYDISVITLINGG-----ESAPTTLTQQTAVP-PPTD 1363
                 V   +    +  T L  G +Y   V  + + G     +S P  +  +   P PP  
Sbjct: 14213 LWTVVSEDIQSCRHVATKLIQGNEYIFRVSAVNHYGKGEPVQSEPVKMVDRFGPPGPPEK 14272

Query: 1364  LRFTNIGPDTMRVTWAPP---PSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLL 1420
                +N+  +T  V+W  P      ++T + V     K+   V  +    SD    +T L 
Sbjct: 14273 PEVSNVTKNTATVSWKRPVDDGGSEITGYHVERREKKSLRWVRAIKTPVSDLRCKVTGLQ 14332

Query: 1421  PGTEYVVSVSSVYEQHESTPLRGRQKTGLDS-------PTGIDFSDITANSFTVHWIAPR 1473
              G+ Y   VS+        P        +         P+    +D T  S ++ W  P 
Sbjct: 14333 EGSTYEFRVSAENRAGIGPPSEASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLAWGKPH 14392

Query: 1474  ----ATITGYRIRHHPEHFSGRPREDRVPHSR-NSITLTNLTPGTEYVVSIVALN--GRE 1526
                   ITGY + H         ++      R     + +L    +Y   I A+N  G  
Sbjct: 14393 YDGGLEITGYVVEHQKVGDEAWIKDTTGTALRITQFVVPDLQTKEKYNFRISAINDAGVG 14452

Query: 1527  ESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFT 1586
             E  ++   +    ++  D E+ A    +L++      +++R +    G      P  E T
Sbjct: 14453 EPAVIPDVEIVEREMAPDFELDAELRRTLVV---RAGLSIRIFVPIKGR-----PAPEVT 14504

Query: 1587  -VPGSKSTATISGLKPGVDYTITVYAVTGRGD---------SPASSKPISINYRTEIDKP 1636
                 + +    + ++    +T+ +     R D         +PA  K   +N R  +D P
Sbjct: 14505 WTKDNINLKNRANIENTESFTLLIIPECNRYDTGKFVMTIENPAGKKSGFVNVRV-LDTP 14563

Query: 1637  S---QMQVTDVQDNSISVKW----LPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMT 1689
                  ++ TD+  +S+++ W    +   S +T Y V            T T    +    
Sbjct: 14564 GPVLNLRPTDITKDSVTLHWDLPLIDGGSRITNYIVEKREATRKS-YSTATTKCHKCTYK 14622

Query: 1690  IEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDR----PKGLAFTDVDVDSIKIAWES 1745
             + GL    EY   V A+N  G  +P   T           P  L   D+   ++ +AW  
Sbjct: 14623 VTGLSEGCEYFFRVMAENEYGIGEPTETTEPVKASEAPSPPDSLNIMDITKSTVSLAWPK 14682

Query: 1746  PQ----GQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHD--- 1798
             P+     +++ Y +                 G E    ++ L  G EYT  V+A++    
Sbjct: 14683 PKHDGGSKITGYVIEAQRKGSDQWTHITTVKGLE--CVVRNLTEGEEYTFQVMAVNSAGR 14740

Query: 1799  --DMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPM 1856
                 ES+P+I  + T +P        Q    + +       + + G R + T   K G  
Sbjct: 14741 SAPRESRPVIVKEQTMLPELDLRGIYQKLVIAKAGDNIKVEIPVLG-RPKPTVTWKKGDQ 14799

Query: 1857  -----KEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVS----- 1906
                  + +N    ++S +++ +    + +   Y     LT+R   G V  +  +      
Sbjct: 14800 ILKQTQRVNFETTATSTILN-INECVRSDSGPY----PLTARNIVGEVGDVITIQVHDIP 14854

Query: 1907  --PPRRARVTDATETTITISWRTKTE----TITGFQVDAVPANGQTPIQRTIKPDVRSYT 1960
               P    +  + +   +T SW          I+ + V+    +  T ++        +Y 
Sbjct: 14855 GPPTGPIKFDEVSSDFVTFSWDPPENDGGVPISNYVVEMRQTDSTTWVELATTVIRTTYK 14914

Query: 1961  ITGLQPGTDYKIYL-----YTLNDNARSSPVVIDASTAIDAPSNL-RFLATTPNSLLVSW 2014
              T L  G +Y+  +     Y +     S+ +V +    +  P    +  A T +S+ +SW
Sbjct: 14915 ATRLTTGLEYQFRVKAQNRYGVGPGITSACIVANYPFKVPGPPGTPQVTAVTKDSMTISW 14974

Query: 2015  QPP----RARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNN 2070
               P     + I GY ++ ++      + V +          +GL  G  Y   VIA    
Sbjct: 14975 HEPLSDGGSPILGYHVERKERNGILWQTVSKALVPGNIFKSSGLTDGIAYEFRVIAENMA 15034

Query: 2071  QKSEP 2075
              KS+P
Sbjct: 15035 GKSKP 15039



 Score =  116 bits (291), Expect = 2e-25
 Identities = 288/1381 (20%), Positives = 498/1381 (36%), Gaps = 191/1381 (13%)

Query: 766  LDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDT 825
            +D  +  TS  I +   G K    +   ++ G+    ++      P    +  V +  D 
Sbjct: 6740 IDTTAEQTSFRILEAKKGDKGRYKIVLQNKHGKAEGFINLKVIDVPGPVRNLEVTETFDG 6799

Query: 826  SIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETAN-SVTLSDLQPG-VQYNIT 879
             + + W  P     + I GY +V    ++  +  L      +   T++ LQ G V+Y   
Sbjct: 6800 EVSLAWEEPLTDGGSKIIGY-VVERRDIKRKTWVLATDRAESCEFTVTGLQKGGVEYLFR 6858

Query: 880  IYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVT 935
            + A        PV          + D    P ++   +V    V++ W PPE    + +T
Sbjct: 6859 VSARNRVGTGEPVETDNPVEARSKYDVPGPPLNVTITDVNRFGVSLTWEPPEYDGGAEIT 6918

Query: 936  GYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTT 995
             Y +++               + +  A VT +  G  Y F+V A +     KP  A    
Sbjct: 6919 NYVIELRDKTSIRWDTAMTVRAEDLSATVTDVVEGQEYSFRVRAQNRIGVGKPSAATPFV 6978

Query: 996  KL-------DAPTNLQFVNETDSTVLVRWTPP----RAQITGYRLTVGLTRRGQPR---- 1040
            K+         P NL   ++T S+V ++W PP     + I GY   +     G+      
Sbjct: 6979 KVADPIERPSPPVNLTSSDQTQSSVQLKWEPPLKDGGSPILGY--IIERCEEGKDNWIRC 7036

Query: 1041 QYNVGPSVSKYPLRNLQPASE--YTVSLVAIKGNQESPKATGVFTT----LQPGSSIPPY 1094
               + P ++ Y +  L+  ++  Y VS     G  +  +  G  T     ++P   +  +
Sbjct: 7037 NMKLVPELT-YKVTGLEKGNKYLYRVSAENKAGVSDPSEILGPLTADDAFVEPTMDLSAF 7095

Query: 1095 NTEV-----TETTIVI--TWTPAPRIGFKLGVRPSQGGEAPREVT-SDSGSIVVSGLTPG 1146
               +        TI++  T  P P   +  G +  + G+  +  T S    +V+S     
Sbjct: 7096 KDGLEVIVPNPITILVPSTGYPRPTATWCFGDKVLETGDRVKMKTLSAYAELVISPSERS 7155

Query: 1147 VEYVYTIQVLRDGQERDAPI-VNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPD--- 1202
             + +YT+++    +     I VN +  P +P      +   D+  LT  WE    PD   
Sbjct: 7156 DKGIYTLKLENRVKTISGEIDVNVIARPSAPKELKFGDITKDSVHLT--WE---PPDDDG 7210

Query: 1203 ---ITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSV------------ 1247
               +TGY +     + +    + + V       T  +L  G EY   V            
Sbjct: 7211 GSPLTGYVVEKREVSRKTWTKVMDFV--TDLEFTVPDLVQGKEYLFKVCARNKCGPGEPA 7268

Query: 1248 YTVKDDKESVPISDTIIPEVPQLTDLSFVDITDSSIGLRWTPLNS---STIIGYRITVVA 1304
            Y  +    S P +   +P+ P+  ++ + D T +SI L W P  +   S I GY +    
Sbjct: 7269 YVDEPVNMSTPAT---VPDPPE--NVKWRDRTANSIFLTWDPPKNDGGSRIKGYIVERCP 7323

Query: 1305 AGE------GIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQ--- 1355
             G       G P+ E  ++       VTGLE G  Y   V  L   G S P+  T++   
Sbjct: 7324 RGSDKWVACGEPVAETKME-------VTGLEEGKWYAYRVKALNRQGASKPSRPTEEIQA 7376

Query: 1356 --TAVPPPTDLRFTNIGPDTMR----------VTWAPPPSIDLTNFLVRYSPVKNEEDVA 1403
              T   P   L    +   T++          VT  P P I  T    +   +  ++   
Sbjct: 7377 VDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWT----KADMILKQDKRI 7432

Query: 1404 ELSISPSDNAVVLTNLL---PGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDI 1460
             +   P  + V + +      GT  + +V+          +    K G   P   D +D+
Sbjct: 7433 TIENVPKKSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNVLDKPG--PPAAFDITDV 7490

Query: 1461 TANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRNS------ITLTNLT 1510
            T  S  + W  PR    + IT Y +         R  +  V H  +S         T L 
Sbjct: 7491 TNESCLLTWNPPRDDGGSKITNYVVER-------RATDSEVWHKLSSTVKDTNFKATKLI 7543

Query: 1511 PGTEYVVSIVALN------GREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAP-- 1562
            P  EY+  + A N        + SP+    Q      P  LE    T  ++ ++W  P  
Sbjct: 7544 PNKEYIFRVAAENMYGVGEPVQASPITAKYQFDPPGPPTRLEPSDITKDAVTLTWCEPDD 7603

Query: 1563 --AVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYA--VTGRGDS 1618
                 +  Y +   +   +  V+   +P   +T  + GL     Y   V A  + G G  
Sbjct: 7604 DGGSPITGYWVERLDPDTDKWVRCNKMPVKDTTYRVKGLTNKKKYRFRVLAENLAGPGKP 7663

Query: 1619 PASSKPISINYRTEID---KPSQMQVTDVQDNSISVKWL----PSSSPVTGYRVTTTPKN 1671
              S++PI I  +  ID    P +  V DV   S+ + W        + +  Y V    K 
Sbjct: 7664 SKSTEPILI--KDPIDPPWPPGKPTVKDVGKTSVRLNWTKPEHDGGAKIESY-VIEMLKT 7720

Query: 1672 GPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQP-------LVQTAVTNID 1724
            G         G   T+  + GL    EY   V A N +GES+P       L +  +    
Sbjct: 7721 GTDEWVRVAEGVPTTQHLLPGLMEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPS 7780

Query: 1725 RPKGLAFTDVDVDSIKIAWESPQ----GQVSRYRVTYSSPEDGIHELFPAPDG--EEDTA 1778
             P+ L   ++  ++  + W  P+      ++ Y V      D   + +   D   ++   
Sbjct: 7781 PPRWLEVINITKNTADLKWTVPEKDGGSPITNYIV---EKRDVRRKGWQTVDTTVKDTKC 7837

Query: 1779 ELQGLRPGSEYTVSVVAL-------HDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSA 1831
             +  L  GS Y   V A        + ++E   L     T    P  L    VT   +  
Sbjct: 7838 TVTPLTEGSLYVFRVAAENAIGQSDYTEIEDSVLAKDTFTTPGPPYALAVVDVTKRHVDL 7897

Query: 1832 QWTPPNVQ--LTGYRVRVTPKEKTGP--MKEINLAPDSSSVVVSGLMVATKYEVSVYALK 1887
            +W PP         R  +  KE+ G   +K    A    +  V+ ++  T+ +  V A  
Sbjct: 7898 KWEPPKNDGGRPIQRYVIEKKERLGTRWVKAGKTAGPDCNFRVTDVIEGTEVQFQVRAEN 7957

Query: 1888 DTLTSRPAQGV-VTTLEN----VSPPRRARVTDATETTITISWRTKTET----ITGFQVD 1938
            +     P++   + ++E+     SPP    VTDA    I I+W+   +     I G+ V+
Sbjct: 7958 EAGVGHPSEPTEILSIEDPTSPPSPPLDLHVTDAGRKHIAIAWKPPEKNGGSPIIGYHVE 8017

Query: 1939 AVPANGQTPIQRTIKP--DVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDA 1996
              P   +  ++   +P  D++     G+ P  +Y + +  +N    S P  I  +     
Sbjct: 8018 MCPVGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAIGVSEPSEISENVVAKD 8077

Query: 1997 P 1997
            P
Sbjct: 8078 P 8078



 Score =  115 bits (288), Expect = 5e-25
 Identities = 291/1449 (20%), Positives = 530/1449 (36%), Gaps = 173/1449 (11%)

Query: 785   KYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPT-VDQVDDTSIVVRWSRPQ----APIT 839
             +Y++ +  ++  G +S+ ++      P  P  P  ++ +      + W RPQ    A I 
Sbjct: 19554 QYVLTLKNVA--GTRSVAVNCKVLDKPGPPAGPLEINGLTAEKCSLSWGRPQEDGGADID 19611

Query: 840   GYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETT 899
              Y +    +   + T         S  ++ L  G +Y   +  V +     P+    E+ 
Sbjct: 19612 YYIVEKRETSHLAWTICEGELQMTSCKVTKLLKGNEYIFRVTGVNKYGVGEPL----ESV 19667

Query: 900   GTPRSD--TVPSP-RDLQFVEVTDVKVTIMWTPPES----AVTGYRVDVIPVN-LPGEHG 951
                  D  TVPSP   L+   VT   +T+ W+ PES     ++GY ++    N L     
Sbjct: 19668 AIKALDPFTVPSPPTSLEITSVTKESMTLCWSRPESDGGSEISGYIIERREKNSLRWVRV 19727

Query: 952   QRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNL-------Q 1004
              + P+  +   + TGL  G  Y ++V+A +    S P       + + P  L       +
Sbjct: 19728 NKKPVY-DLRVKSTGLREGCEYEYRVYAENAAGLSLPSETSPLIRAEDPVFLPSPPSKPK 19786

Query: 1005  FVNETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPAS 1060
              V+   +T+ + W  P     A ITGY +    +     +        ++Y +  L   +
Sbjct: 19787 IVDSGKTTITIAWVKPLFDGGAPITGYTVEYKKSDDTDWKTSIQSLRGTEYTISGLTTGA 19846

Query: 1061  EYTVSLVAIK---GNQESPKATGVFTTLQPGSSIPPYNTEVTETTIV-----ITWT---- 1108
             EY   + ++     +  S  +       +    +   ++E+ +T IV      T T    
Sbjct: 19847 EYVFRVKSVNKVGASDPSDSSDPQIAKEREEEPLFDIDSEMRKTLIVKAGASFTMTVPFR 19906

Query: 1109  --PAPRIGFKLGVRPSQG--GEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDA 1164
               P P +   L  +P       A  + T    S+ +          YT+ +         
Sbjct: 19907 GRPVPNV---LWSKPDTDLRTRAYVDTTDSRTSLTIENANRNDSGKYTLTIQNVLSAASL 19963

Query: 1165  PIVNKVVTPLSPPTNLHLE-ANPDTGVLTVSW---ERSTTPDITGYRITTTPTNGQQGNS 1220
              +V KV+    PPTN+ ++    ++ VL  SW   E      +  Y I     + +   S
Sbjct: 19964 TLVVKVLDTPGPPTNITVQDVTKESAVL--SWDVPENDGGAPVKNYHIEKREASKKAWVS 20021

Query: 1221  LE--------EVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPEVPQLTD 1272
             +         +V +  + +  +  +S   E+ V +    + KE V I++   P  P+   
Sbjct: 20022 VTNNCNRLSYKVTNLQEGAIYYFRVSGENEFGVGIPA--ETKEGVKITEK--PSPPE--K 20075

Query: 1273  LSFVDITDSSIGLRWTPLN---SSTIIGYRITVVAAGEGIPIFEDFVDSSVG---YYTVT 1326
             L    I+  S+ L W        S I+ Y +  +  G+     +++V  +V    ++ V+
Sbjct: 20076 LGVTSISKDSVSLTWLKPEHDGGSRIVHYVVEALEKGQ-----KNWVKCAVAKSTHHVVS 20130

Query: 1327  GLEPGIDYDISVITLINGGESAPT-----TLTQQTAVPPPTDLRFTNIGPDTMRVTWAPP 1381
             GL    +Y   V      G S P       L ++   PP  D++  N    T+ V     
Sbjct: 20131 GLRENSEYFFRVFAENQAGLSDPRELLLPVLIKEQLEPPEIDMK--NFPSHTVYVRAGSN 20188

Query: 1382  PSIDLTNFLVRYSPVKNEEDVAELSISPSDNA-VVLTNLLPGTEYVVSVSSVYEQHESTP 1440
               +D+         V    D   L  +   N  +   NL    +  V+  +   +  +  
Sbjct: 20189 LKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADAGRYEITAAN 20248

Query: 1441  LRGRQKTGLD--------SPTG-IDFSDITANSFTVHWIAPR----ATITGYRIRHHPEH 1487
               G  K  ++         PTG +  SDIT  S T+ W  P+    + +T Y +    E 
Sbjct: 20249 SSGTTKAFINIVVLDRPGPPTGPVVISDITEESVTLKWEPPKYDGGSQVTNYILLKR-ET 20307

Query: 1488  FSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGR------EESPLLIGQQSTVSDV 1541
              +    E     +R  + +  LT G EY   I A N        + + + +    T    
Sbjct: 20308 STAVWTEVSATVARTMMKVMKLTTGEEYQFRIKAENRFGISDHIDSACVTVKLPYTTPGP 20367

Query: 1542  PRDLEVVAATPTSLLISWDAPAVT----VRYYRITYGETGGNSPVQEFTVPGSKSTATIS 1597
             P    V   T  S+ + W  P       V  Y +   +       +   +    +   ++
Sbjct: 20368 PSTPWVTNVTRESITVGWHEPVSNGGSAVVGYHLEMKDRNSILWQKANKLVIRTTHFKVT 20427

Query: 1598  GLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKW---- 1653
              +  G+ Y   VYA    G    S     +      + P  +++TD+  NS+S+ W    
Sbjct: 20428 TISAGLIYEFRVYAENAAGVGKPSHPSEPVLAIDACEPPRNVRITDISKNSVSLSWQQPA 20487

Query: 1654  LPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE-S 1712
                 S +TGY V          TK       +T+  I GL    +Y   V+A+N  G  S
Sbjct: 20488 FDGGSKITGYIVERRDLPDGRWTKASFTNVTETQFIISGLTQNSQYEFRVFARNAVGSIS 20547

Query: 1713  QPL-VQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAP 1771
              P  V   +T ID   G    D+ ++  ++  +   G   + R   S       E +   
Sbjct: 20548 NPSEVVGPITCIDSYGGPVI-DLPLEYTEVV-KYRAGTSVKLRAGISGKPAPTIEWYK-D 20604

Query: 1772  DGEEDTAELQGLRPGSEYTVSVVALHDDMES-------QPLIGTQSTAI---------PA 1815
             D E  T  L  +   ++    ++   D + S       +  +G+ S  I         P 
Sbjct: 20605 DKELQTNALVCVENTTDLASILIKDADRLNSGCYELKLRNAMGSASATIRVQILDKPGPP 20664

Query: 1816  PTDLKFTQVTPTSLSAQWTPP----NVQLTGYRVRVTPKEKTGPM--KEINLAPDSSSVV 1869
                ++F  VT   ++  W PP      ++T Y   +  K +T  +    ++   +   + 
Sbjct: 20665 GGPIEFKTVTAEKITLLWRPPADDGGAKITHY---IVEKRETSRVVWSMVSEHLEECIIT 20721

Query: 1870  VSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENV----SPPRRARVTDATETTITISW 1925
              + ++   +Y   V A+       P +      +N      PP    VT  T+ ++T+ W
Sbjct: 20722 TTKIIKGNEYIFRVRAVNKYGIGEPLESDSVVAKNAFVTPGPPGIPEVTKITKNSMTVVW 20781

Query: 1926  RTKT----ETITGFQV---DAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLN 1978
                       I+G+ +   D         ++ TI+ D R   +TGL   +DY+  +  +N
Sbjct: 20782 SRPIADGGSDISGYFLEKRDKKSLGWFKVLKETIR-DTRQ-KVTGLTENSDYQYRVCAVN 20839

Query: 1979  DNAR---SSPVVI-DASTAIDAP---SNLRFLATTPNSLLVSWQPP----RARITGYIIK 2027
                +   S P     A+  ID P   + +R   +T +S+ + W  P     + +TGY+++
Sbjct: 20840 AAGQGPFSEPSEFYKAADPIDPPGPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVVE 20899

Query: 2028  YEKPGSPPREVVP-RPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQKT 2086
               +        V  +     TE  ++ L+PG  Y   V A+    + EP I   + VQ  
Sbjct: 20900 IRQGEEEEWTTVSTKGEVRTTEYVVSNLKPGVNYYFRVSAVNCAGQGEP-IEMNEPVQAK 20958

Query: 2087  PFVTHPGYD 2095
               +  P  D
Sbjct: 20959 DILEAPEID 20967



 Score =  115 bits (287), Expect = 7e-25
 Identities = 310/1519 (20%), Positives = 528/1519 (34%), Gaps = 242/1519 (15%)

Query: 758  EEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLI---LSTSQTTAPDAP 814
            E GD  +   L + A  V    + P  +    +Y +  +     I   +  +    P AP
Sbjct: 7131 ETGDRVKMKTLSAYAELV----ISPSERSDKGIYTLKLENRVKTISGEIDVNVIARPSAP 7186

Query: 815  PDPTVDQVDDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTLSDL 870
             +     +   S+ + W  P     +P+TGY +        + T++    T    T+ DL
Sbjct: 7187 KELKFGDITKDSVHLTWEPPDDDGGSPLTGYVVEKREVSRKTWTKVMDFVTDLEFTVPDL 7246

Query: 871  QPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP 930
              G +Y   + A  +     P  + +    +  +     P ++++ + T   + + W PP
Sbjct: 7247 VQGKEYLFKVCARNKCGPGEPAYVDEPVNMSTPATVPDPPENVKWRDRTANSIFLTWDPP 7306

Query: 931  E----SAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRES 986
            +    S + GY V+  P           P++  T  EVTGL  G  Y ++V A++    S
Sbjct: 7307 KNDGGSRIKGYIVERCPRGSDKWVACGEPVA-ETKMEVTGLEEGKWYAYRVKALNRQGAS 7365

Query: 987  KP---------------------------LTAQQTTKLDAPTNLQFVNETDSTVLVRWTP 1019
            KP                           LT +  TK++ P  +    E   T    WT 
Sbjct: 7366 KPSRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKIT----WT- 7420

Query: 1020 PRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKAT 1079
             +A +   +    +T    P++  V    SK           Y +  V + G   +    
Sbjct: 7421 -KADMI-LKQDKRITIENVPKKSTVTIVDSK-----RSDTGTYIIEAVNVCGRATAVVEV 7473

Query: 1080 GVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRI--GFKLGVRPSQGGEAPREVTSDSGS 1137
             V    +PG       T+VT  + ++TW P PR   G K+     +      EV     S
Sbjct: 7474 NVLD--KPGPPAAFDITDVTNESCLLTWNP-PRDDGGSKITNYVVERRATDSEVWHKLSS 7530

Query: 1138 IV------VSGLTPGVEYVYTI---QVLRDGQERDA-PIVNKV-VTPLSPPTNLHLEANP 1186
             V       + L P  EY++ +    +   G+   A PI  K    P  PPT L   ++ 
Sbjct: 7531 TVKDTNFKATKLIPNKEYIFRVAAENMYGVGEPVQASPITAKYQFDPPGPPTRLE-PSDI 7589

Query: 1187 DTGVLTVSW---ERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEY 1243
                +T++W   +      ITGY +     +  +     ++   D ++     L+   +Y
Sbjct: 7590 TKDAVTLTWCEPDDDGGSPITGYWVERLDPDTDKWVRCNKMPVKD-TTYRVKGLTNKKKY 7648

Query: 1244 NVSVYTV------KDDKESVP--ISDTIIPEVPQLTDLSFVDITDSSIGLRWTPL---NS 1292
               V         K  K + P  I D I P  P     +  D+  +S+ L WT       
Sbjct: 7649 RFRVLAENLAGPGKPSKSTEPILIKDPIDPPWPP-GKPTVKDVGKTSVRLNWTKPEHDGG 7707

Query: 1293 STIIGYRITVVAAG--------EGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLING 1344
            + I  Y I ++  G        EG+P  +         + + GL  G +Y   V  +   
Sbjct: 7708 AKIESYVIEMLKTGTDEWVRVAEGVPTTQ---------HLLPGLMEGQEYSFRVRAVNKA 7758

Query: 1345 GESAPT-----TLTQQTAVP--PPTDLRFTNIGPDTMRVTWAPPP---SIDLTNFLVRYS 1394
            GES P+      L ++   P  PP  L   NI  +T  + W  P       +TN++V   
Sbjct: 7759 GESEPSEPSDPVLCREKLYPPSPPRWLEVINITKNTADLKWTVPEKDGGSPITNYIVEKR 7818

Query: 1395 PVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVS-------SVYEQHESTPLRGRQKT 1447
             V+  +    +  +  D    +T L  G+ YV  V+       S Y + E + L     T
Sbjct: 7819 DVR-RKGWQTVDTTVKDTKCTVTPLTEGSLYVFRVAAENAIGQSDYTEIEDSVLAKDTFT 7877

Query: 1448 GLDSPTGIDFSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRNS 1503
                P  +   D+T     + W  P+      I  Y I       +   +  +      +
Sbjct: 7878 TPGPPYALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKERLGTRWVKAGKTAGPDCN 7937

Query: 1504 ITLTNLTPGTEYVVSIVALN----GREESP---LLIGQQSTVSDVPRDLEVVAATPTSLL 1556
              +T++  GTE    + A N    G    P   L I   ++    P DL V  A    + 
Sbjct: 7938 FRVTDVIEGTEVQFQVRAENEAGVGHPSEPTEILSIEDPTSPPSPPLDLHVTDAGRKHIA 7997

Query: 1557 ISWDAPAVTVRYYRITYGETGGNSPVQEFTVP----GSKSTATIS-------------GL 1599
            I+W  P            E  G SP+  + V     G++    ++             G+
Sbjct: 7998 IAWKPP------------EKNGGSPIIGYHVEMCPVGTEKWMRVNSRPIKDLKFKVEEGV 8045

Query: 1600 KPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSP 1659
             P  +Y + V AV   G     S+P  I+       P      D++ + I V      S 
Sbjct: 8046 VPDKEYVLRVRAVNAIG----VSEPSEISENVVAKDPDCKPTIDLETHDIIVIEGEKLSI 8101

Query: 1660 VTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYA---------QNPSG 1710
               +R    P         +    D+  M  + +   +E   SV A         +N  G
Sbjct: 8102 PVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLG 8161

Query: 1711 ESQPLVQTAVTNIDRP-KGLAFTDVDVDSIKIAWESPQ--GQVSRYRVTYSSPEDGIHEL 1767
             +   +   V  +  P K +  +D+   S K+ WE P+  G            E G    
Sbjct: 8162 SATASINVKVIGLPGPCKDIKASDITKSSCKLTWEPPEFDGGTPILHYVLERREAGRRTY 8221

Query: 1768 FPAPDGEEDTA-ELQGLRPGSEYTVSVVALH-----DDME-SQPLIGTQSTAIP-APTDL 1819
             P   GE   +  ++ L P  EY   V A++     + +E   P+I       P  P D+
Sbjct: 8222 IPVMSGENKLSWTVKDLIPNGEYFFRVKAVNKVGGGEYIELKNPVIAQDPKQPPDPPVDV 8281

Query: 1820 KFTQVTPTSLSAQWTPP----NVQLTGYRV-RVTPKEKTGPMKEINLAPDSSSVVVSGLM 1874
            +    T  +++  W PP      ++ GY + ++   E+       +L P   +    GL 
Sbjct: 8282 EVHNPTAEAMTITWKPPLYDGGSKIMGYIIEKIAKGEERWKRCNEHLVP-ILTYTAKGLE 8340

Query: 1875 VATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTI------------- 1921
               +Y+  V A      S P++    T + V P    +V   T   +             
Sbjct: 8341 EGKEYQFRVRAENAAGISEPSRATPPT-KAVDPIDAPKVILRTSLEVKRGDEIALDASIS 8399

Query: 1922 -----TISWRTKTETITGFQVD--------------------AVPANGQTPIQRTIKPDV 1956
                 TI+W      I   ++                      +P   +  I  + K + 
Sbjct: 8400 GSPYPTITWIKDENVIVPEEIKKRAAPLVRRRKGEVQEEEPFVLPLTQRLSIDNSKKGES 8459

Query: 1957 RSYTITGLQPGTDYKIYLYTL-NDNA-RSSPVVIDASTAIDAPSNLRFLATTPNSLLVSW 2014
            +      L+P  D+ +Y+  + ND+    +P  +        P N  F      S+L  W
Sbjct: 8460 QLRVRDSLRP--DHGLYMIKVENDHGIAKAPCTVSVLDTPGPPINFVFEDIRKTSVLCKW 8517

Query: 2015 QPP----RARITGYIIKYEKPGSPPRE-VVPRPRPGVTEATITGLEPGTEYTIYVIALKN 2069
            +PP     + I  Y ++ +    P  E +V        + ++T L  G EY ++ +  +N
Sbjct: 8518 EPPLDDGGSEIINYTLEKKDKTKPDSEWIVVTSTLRHCKYSVTKLIEGKEY-LFRVRAEN 8576

Query: 2070 NQKSEPLIGRKKTVQKTPF 2088
                 P    K  V K PF
Sbjct: 8577 RFGPGPPCVSKPLVAKDPF 8595



 Score =  114 bits (286), Expect = 9e-25
 Identities = 280/1356 (20%), Positives = 495/1356 (36%), Gaps = 217/1356 (16%)

Query: 727   SVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQ--YLDLPSTA--TSVNIPDLLP 782
             +VTE+T+   V+SW    D   G ++++ + ++ +  +  + ++ S    T + +  LL 
Sbjct: 15258 AVTEVTSEKCVLSWFPPLDD-GGAKIDHYIVQKRETSRLAWTNVASEVQVTKLKVTKLLK 15316

Query: 783   GRKYI-----VNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAP 837
             G +YI     VN Y + E  E   +L+ +    PD P +P V  +   S+VV W  P + 
Sbjct: 15317 GNEYIFRVMAVNKYGVGEPLESEPVLAVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDS- 15375

Query: 838   ITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQ-------PGVQYNITIYAVEENQEST 890
               G   + +  VE            N  TL+DL+        G +Y   I A      S 
Sbjct: 15376 -DGGSEIINYIVERRDKAGQRWIKCNKKTLTDLRYKVSGLTEGHEYEFRIMAENAAGISA 15434

Query: 891   PVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNL 946
             P                  P + + ++ +   ++I W  P     S +TGY V++    L
Sbjct: 15435 PSPTSPFYKACDTVFKPGPPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIA---L 15491

Query: 947   PGEHGQRLPIS----RNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLD---A 999
             P E   ++       + T   +TGL+    Y  +++A++     +P     T K +    
Sbjct: 15492 PEEDEWQIVTPPAGLKATSYTITGLTENQEYKIRIYAMNSEGLGEPALVPGTPKAEDRML 15551

Query: 1000  PTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPR---QYNVGPSVSKYPLRNL 1056
             P  ++   +    V +R           RL V +  R  P      + G S+ K    ++
Sbjct: 15552 PPEIELDADLRKVVTIR------ACCTLRLFVPIKGRPAPEVKWARDHGESLDK---ASI 15602

Query: 1057  QPASEYTVSLVAIKGNQESPK----------ATGVFTTLQ----PGSSIPPYNTEVTETT 1102
             +  S YT+ +V      +S K          +   F  ++    PG        EVT+T+
Sbjct: 15603 ESTSSYTLLIVGNVNRFDSGKYILTVENSSGSKSAFVNVRVLDTPGPPQDLKVKEVTKTS 15662

Query: 1103  IVITWTPAPRI--GFKLGVRPSQGGEAPREVTS------DSGSIVVSGLTPGVEYVYTIQ 1154
             + +TW P P +  G K+     +  E+ R+  S         S  V  L  G  Y +  +
Sbjct: 15663 VTLTWDP-PLLDGGSKIKNYIVEKRESTRKAYSTVATNCHKTSWKVDQLQEGCSYYF--R 15719

Query: 1155  VLRDGQ------ERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPD---ITG 1205
             VL + +         A  V     PL P     ++   ++  +++SWE+        I G
Sbjct: 15720 VLAENEYGIGLPAETAESVKASERPLPPGKITLMDVTRNS--VSLSWEKPEHDGGSRILG 15777

Query: 1206  YRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYT-----VKDDKE-SVPI 1259
             Y I    T G    +    V   +++ T   L  G EY+  V       + D ++ SVP+
Sbjct: 15778 Y-IVEMQTKGSDKWATCATVKVTEATIT--GLIQGEEYSFRVSAQNEKGISDPRQLSVPV 15834

Query: 1260  --SDTIIPEVPQLTDLSFVDITDSSI------------GLRW----TPLNSSTIIGYRIT 1301
                D +IP   +L   +F  +    +             + W     PL  +T +    T
Sbjct: 15835 IAKDLVIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAEST 15894

Query: 1302  VVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTL---TQQTAV 1358
                    +   +D     VG+Y              V+ L N    A  TL         
Sbjct: 15895 ---ENNSLLTIKDACREDVGHY--------------VVKLTNSAGEAIETLNVIVLDKPG 15937

Query: 1359  PPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAE---LSISPSDNAVV 1415
             PP   ++   +  D++ ++W  PP  D  + +  Y   K +        +S + +   + 
Sbjct: 15938 PPTGPVKMDEVTADSITLSWG-PPKYDGGSSINNYIVEKRDTSTTTWQIVSATVARTTIK 15996

Query: 1416  LTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTG-----LDSPTGIDFSDITA-NSFTVHW 1469
                L  G EY   +++     +ST L            +  P G     +++ +S  V W
Sbjct: 15997 ACRLKTGCEYQFRIAAENRYGKSTYLNSEPTVAQYPFKVPGPPGTPVVTLSSRDSMEVQW 16056

Query: 1470  IAP----RATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGR 1525
               P     + + GY +     +     + ++ P  +     T L  G EY   + A    
Sbjct: 16057 NEPISDGGSRVIGYHLERKERNSILWVKLNKTPIPQTKFKTTGLEEGVEYEFRVSA---- 16112

Query: 1526  EESPLLIGQQSTVSD--VPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQ 1583
              E+ + IG+ S VS+  V RD       P +++++ +  +VT+++ + TY    G S + 
Sbjct: 16113 -ENIVGIGKPSKVSECYVARDPCDPPGRPEAIIVTRN--SVTLQWKKPTY---DGGSKIT 16166

Query: 1584  EFTVPGS--------KSTAT--------ISGLKPGVDYTITVYAVTGRG-DSPASSKPIS 1626
              + V           K++ T        ++GL     Y   V A    G  S  S    +
Sbjct: 16167 GYIVEKKELPEGRWMKASFTNIIDTHFEVTGLVEDHRYEFRVIARNAAGVFSEPSESTGA 16226

Query: 1627  INYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQT 1686
             I  R E+D P        +D  +             ++V       P PT     G  + 
Sbjct: 16227 ITARDEVDPPRISMDPKYKDTIV-------VHAGESFKVDADIYGKPIPTIQWIKGDQEL 16279

Query: 1687  EMTIEGLQPTVEYVVS---------------VYAQNPSGESQPLVQTAVTNIDRP----K 1727
               T      + ++  S               + A+N +GE    V   V  +DRP     
Sbjct: 16280 SNTARLEIKSTDFATSLSVKDAVRVDSGNYILKAKNVAGERSVTVNVKV--LDRPGPPEG 16337

Query: 1728  GLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHEL-FPAPDGEEDT--AELQGLR 1784
              +  + V  +   +AW+ P        + Y         L +   D    T   ++  L 
Sbjct: 16338 PVVISGVTAEKCTLAWKPPLQDGGSDIINYIVERRETSRLVWTVVDANVQTLSCKVTKLL 16397

Query: 1785  PGSEYTVSVVALH-----DDMESQPLIGTQSTAIP-APTDLKFTQVTPTSLSAQWTPP-- 1836
              G+EYT  ++A++     + +ES+P++      +P AP   + T VT  S+   W  P  
Sbjct: 16398 EGNEYTFRIMAVNKYGVGEPLESEPVVAKNPFVVPDAPKAPEVTTVTKDSMIVVWERPAS 16457

Query: 1837  --NVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRP 1894
                 ++ GY +    KE     +          + V+GL+    YE  V A      S P
Sbjct: 16458 DGGSEILGYVLEKRDKEGIRWTRCHKRLIGELRLRVTGLIENHDYEFRVSAENAAGLSEP 16517

Query: 1895  A-----QGVVTTLENVSPPRRARVTDATETTITISW 1925
             +     Q     +    PP   +V D T +++ +SW
Sbjct: 16518 SPPSAYQKACDPIYKPGPPNNPKVIDITRSSVFLSW 16553



 Score =  114 bits (285), Expect = 1e-24
 Identities = 294/1413 (20%), Positives = 501/1413 (35%), Gaps = 193/1413 (13%)

Query: 806  SQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ----APITGYRIVYSPSVEGS-STELNLPE 860
            S+   P  P + T+  V+   + + W  P+    A IT Y I           T + +  
Sbjct: 6881 SKYDVPGPPLNVTITDVNRFGVSLTWEPPEYDGGAEITNYVIELRDKTSIRWDTAMTVRA 6940

Query: 861  TANSVTLSDLQPGVQYNITIYA-----VEENQESTPVVIQQETTGTPRSDTVPSPRDLQF 915
               S T++D+  G +Y+  + A     V +   +TP V   +    P       P +L  
Sbjct: 6941 EDLSATVTDVVEGQEYSFRVRAQNRIGVGKPSAATPFVKVADPIERPSP-----PVNLTS 6995

Query: 916  VEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGV 971
             + T   V + W PP     S + GY ++             + +      +VTGL  G 
Sbjct: 6996 SDQTQSSVQLKWEPPLKDGGSPILGYIIERCEEGKDNWIRCNMKLVPELTYKVTGLEKGN 7055

Query: 972  TYYFKVFAVSHGRESKP------LTA-----QQTTKLDA-PTNLQFVNETDSTVLVRWTP 1019
             Y ++V A +    S P      LTA     + T  L A    L+ +     T+LV  T 
Sbjct: 7056 KYLYRVSAENKAGVSDPSEILGPLTADDAFVEPTMDLSAFKDGLEVIVPNPITILVPSTG 7115

Query: 1020 -PRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKA 1078
             PR   T       L    + +      ++S Y    + P+      +  +K        
Sbjct: 7116 YPRPTATWCFGDKVLETGDRVKM----KTLSAYAELVISPSERSDKGIYTLKLENRVKTI 7171

Query: 1079 TG---VFTTLQPGSSIPPYNTEVTETTIVITWTP------APRIGFKLGVRPSQGGEAPR 1129
            +G   V    +P +       ++T+ ++ +TW P      +P  G+ +  R     E  R
Sbjct: 7172 SGEIDVNVIARPSAPKELKFGDITKDSVHLTWEPPDDDGGSPLTGYVVEKR-----EVSR 7226

Query: 1130 EVTSDSGSIV------VSGLTPGVEYVYTIQVLRDGQERDAPIVNKVV---TPLS---PP 1177
            +  +     V      V  L  G EY++ +         +   V++ V   TP +   PP
Sbjct: 7227 KTWTKVMDFVTDLEFTVPDLVQGKEYLFKVCARNKCGPGEPAYVDEPVNMSTPATVPDPP 7286

Query: 1178 TNLHLEANPDTGVLTVSWERSTTPD---ITGYRITTTPTNGQQGNSLEEVVHADQSSCTF 1234
             N+         +  ++W+         I GY +   P    +  +  E V   +   T 
Sbjct: 7287 ENVKWRDRTANSIF-LTWDPPKNDGGSRIKGYIVERCPRGSDKWVACGEPVAETKMEVT- 7344

Query: 1235 DNLSPGLEYNVSVYTVKDDKESVPISDT-------------IIPEVPQLTDLSF-----V 1276
              L  G  Y   V  +     S P   T             I  +V  L  L+      +
Sbjct: 7345 -GLEEGKWYAYRVKALNRQGASKPSRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKI 7403

Query: 1277 DITDSSIG-----LRWTPLNSSTIIGYRITVVAAGEGIP-----IFEDFVDSSVGYYTVT 1326
            ++  +  G     + WT  +       RIT+    E +P        D   S  G Y + 
Sbjct: 7404 ELPATVTGKPEPKITWTKADMILKQDKRITI----ENVPKKSTVTIVDSKRSDTGTYIIE 7459

Query: 1327 GLEPGIDYDISVITLINGGESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAPPPS--- 1383
             +             + G  +A   +       PP     T++  ++  +TW PP     
Sbjct: 7460 AVN------------VCGRATAVVEVNVLDKPGPPAAFDITDVTNESCLLTWNPPRDDGG 7507

Query: 1384 IDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSS-----VYEQHES 1438
              +TN++V      +E    +LS +  D     T L+P  EY+  V++     V E  ++
Sbjct: 7508 SKITNYVVERRATDSEV-WHKLSSTVKDTNFKATKLIPNKEYIFRVAAENMYGVGEPVQA 7566

Query: 1439 TPLRGR-QKTGLDSPTGIDFSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPR 1493
            +P+  + Q      PT ++ SDIT ++ T+ W  P     + ITGY +           R
Sbjct: 7567 SPITAKYQFDPPGPPTRLEPSDITKDAVTLTWCEPDDDGGSPITGYWVERLDPDTDKWVR 7626

Query: 1494 EDRVPHSRNSITLTNLTPGTEYVVSIVALN-------GREESPLLIGQQSTVSDVPRDLE 1546
             +++P    +  +  LT   +Y   ++A N        +   P+LI         P    
Sbjct: 7627 CNKMPVKDTTYRVKGLTNKKKYRFRVLAENLAGPGKPSKSTEPILIKDPIDPPWPPGKPT 7686

Query: 1547 VVAATPTSLLISWDAP----AVTVRYYRITYGETGGNSPVQEFTVPGSKSTA-TISGLKP 1601
            V     TS+ ++W  P       +  Y I   +TG +  V+     G  +T   + GL  
Sbjct: 7687 VKDVGKTSVRLNWTKPEHDGGAKIESYVIEMLKTGTDEWVR--VAEGVPTTQHLLPGLME 7744

Query: 1602 GVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQ---MQVTDVQDNSISVKWL---- 1654
            G +Y+  V AV   G+S  S     +  R ++  PS    ++V ++  N+  +KW     
Sbjct: 7745 GQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLEVINITKNTADLKWTVPEK 7804

Query: 1655 PSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQ- 1713
               SP+T Y V        G     T   D T+ T+  L     YV  V A+N  G+S  
Sbjct: 7805 DGGSPITNYIVEKRDVRRKGWQTVDTTVKD-TKCTVTPLTEGSLYVFRVAAENAIGQSDY 7863

Query: 1714 ------PLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQ----VSRYRVTYSSPEDG 1763
                   L +   T    P  LA  DV    + + WE P+      + RY +        
Sbjct: 7864 TEIEDSVLAKDTFTTPGPPYALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKERLGT 7923

Query: 1764 IHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPT------ 1817
                     G +    +  +  G+E    V A ++     P   T+  +I  PT      
Sbjct: 7924 RWVKAGKTAGPDCNFRVTDVIEGTEVQFQVRAENEAGVGHPSEPTEILSIEDPTSPPSPP 7983

Query: 1818 -DLKFTQVTPTSLSAQWTPPNVQ----LTGYRVRVTPKEKTGPMKEINLAP--DSSSVVV 1870
             DL  T      ++  W PP       + GY V + P   T     +N  P  D    V 
Sbjct: 7984 LDLHVTDAGRKHIAIAWKPPEKNGGSPIIGYHVEMCP-VGTEKWMRVNSRPIKDLKFKVE 8042

Query: 1871 SGLMVATKYEVSVYALKDTLTSRP---AQGVVTTLENVSP-----PRRARVTDATETTIT 1922
             G++   +Y + V A+     S P   ++ VV    +  P          V +  + +I 
Sbjct: 8043 EGVVPDKEYVLRVRAVNAIGVSEPSEISENVVAKDPDCKPTIDLETHDIIVIEGEKLSIP 8102

Query: 1923 ISWRTKTETITGFQVDAVPANGQTPIQRTIKPD-VRSYTITGLQPGTDYKIYLYTLNDNA 1981
            + +R        +  D         +  T+K D + ++         D  IY  TL +  
Sbjct: 8103 VPFRAVPVPTVSWHKDGKEVKASDRL--TMKNDHISAHLEVPKSVRADAGIYTITLENKL 8160

Query: 1982 RSSPVVIDAST-AIDAP-SNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPP 2035
             S+   I+     +  P  +++    T +S  ++W+PP       I  Y+++  + G   
Sbjct: 8161 GSATASINVKVIGLPGPCKDIKASDITKSSCKLTWEPPEFDGGTPILHYVLERREAGR-- 8218

Query: 2036 REVVP-RPRPGVTEATITGLEPGTEYTIYVIAL 2067
            R  +P          T+  L P  EY   V A+
Sbjct: 8219 RTYIPVMSGENKLSWTVKDLIPNGEYFFRVKAV 8251



 Score =  112 bits (281), Expect = 3e-24
 Identities = 353/1634 (21%), Positives = 588/1634 (35%), Gaps = 247/1634 (15%)

Query: 607   SSSGPVEVFIT----ETPSQPNSHPIQWNAPQPSHISKYILRWRP---------KNSVGR 653
             +SSG    F+T    +TP  P +  ++      +      L W P         KN V  
Sbjct: 17794 NSSGSKSAFVTVKVLDTPGPPQNLAVKEVRKDSA-----FLVWEPPIIDGGAKVKNYVID 17848

Query: 654   WKEATIPGHLN--------SYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTP 705
              +E+T   + N        S+ ++ L  G +Y  ++++  ++G                P
Sbjct: 17849 KRESTRKAYANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFG-------------VGVP 17895

Query: 706   VTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVS----ASDTVSGFRVEYELSEEGD 761
             V +        P SP      ++T+++ +S  + W          V G+ VE  +  +G 
Sbjct: 17896 VETVDAVKAAEPPSP--PGKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVE--MQPKGT 17951

Query: 762   EPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQ 821
             E   +   S   +  +  L  G++Y   V   +E G+    +      A D    P++  
Sbjct: 17952 EKWSIVAESKVCNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKL 18011

Query: 822   VDDTSIVVRWS--RPQAPITGY-RIVYSPSVEGS----STELNLPETANSVTLSDLQPGV 874
               +T  +      + + P+ G  R   S   +G     +T +N+ ETA S  L  ++ G 
Sbjct: 18012 PFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLH-IKEGN 18070

Query: 875   QYNITIYAVEENQESTPV-----VIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTP 929
             + +   Y V     +        VI  E  G P          ++F EV+   V I W P
Sbjct: 18071 KDDFGKYTVTATNSAGTATENLSVIVLEKPGPPVGP-------VRFDEVSADFVVISWEP 18123

Query: 930   PESA----VTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRE 985
             P       ++ Y V+         H     ++R T  ++T L  G  Y F++FA +   +
Sbjct: 18124 PAYTGGCQISNYIVEKRDTTTTTWHMVSATVARTTI-KITKLKTGTEYQFRIFAENRYGK 18182

Query: 986   SKPLTA-----QQTTKLDAPTNLQFVNE-TDSTVLVRWTPP----RAQITGYRLTVGLTR 1035
             S PL +     Q   K   P    FV   +   +LV+W  P      +I GY L      
Sbjct: 18183 SAPLDSKAVIVQYPFKEPGPPGTPFVTSISKDQMLVQWHEPVNDGGTKIIGYHLEQKEKN 18242

Query: 1036  RGQPRQYNVGP-SVSKYPLRNLQPASEY--TVSLVAIKGNQESPKATGVFTTLQPGSSIP 1092
                  + N  P   +K+    L    EY   VS   I G  +  K +  F    P    P
Sbjct: 18243 SILWVKLNKTPIQDTKFKTTGLDEGLEYEFKVSAENIVGIGKPSKVSECFVARDPCD--P 18300

Query: 1093  PYNTE---VTETTIVITW-TPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVE 1148
             P   E   +T   + + W  PA   G K+       G    +     G  + +  T  +E
Sbjct: 18301 PGRPEAIVITRNNVTLKWKKPAYDGGSKI------TGYIVEKKDLPDGRWMKASFTNVLE 18354

Query: 1149  YVYTIQVLRDGQERDAPIV-NKVVTPLSPPT---------------NLHLEAN-PDTGVL 1191
               +T+  L + Q  +  ++        S P+               N  L+    D  V+
Sbjct: 18355 TEFTVSGLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARDEIDAPNASLDPKYKDVIVV 18414

Query: 1192  TVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNL---------SPGLE 1242
                       DI G  I     + + G  LEE     +   T             + G +
Sbjct: 18415 HAGETFVLEADIRGKPIPDVVWS-KDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQ 18473

Query: 1243  YNVSVYTVKDDKESVPISDTIIPEV-PQLTDLSFVDITDSSIGLRWTP--LNSSTIIGYR 1299
             Y + +  V   K S+PI+  ++    P    L    +T     L W P   +    I + 
Sbjct: 18474 YILKLSNVGGTK-SIPITVKVLDRPGPPEGPLKVTGVTAEKCYLAWNPPLQDGGANISHY 18532

Query: 1300  ITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGG-----ESAPTTLTQ 1354
             I        +   +   +     Y VT L PG +Y   V+ +   G     ES P T   
Sbjct: 18533 IIEKRETSRLSWTQVSTEVQALNYKVTKLLPGNEYIFRVMAVNKYGIGEPLESGPVTACN 18592

Query: 1355  QTAVP-PPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISP---S 1410
                 P PP+    + I  D+M VTWA P     T         +++E V     +    +
Sbjct: 18593 PYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDKEGVRWTKCNKKTLT 18652

Query: 1411  DNAVVLTNLLPGTEYVVSVSS-----VYEQHESTPLRGRQKTGL---DSPTGIDFSDITA 1462
             D  + +T L  G  Y   V++     V E  E +    R    L     P+    +D + 
Sbjct: 18653 DLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFY-RACDALYPPGPPSNPKVTDTSR 18711

Query: 1463  NSFTVHWIAP----RATITGYRIRHHPEHFSGRPREDRVPHS---RNSITLTNLTPGTEY 1515
             +S ++ W  P     A + GY +    +  +        P +       T+T L   TEY
Sbjct: 18712 SSVSLAWSKPIYDGGAPVKGYVV--EVKEAAADEWTTCTPPTGLQGKQFTVTKLKENTEY 18769

Query: 1516  VVSIVALN--GREESPLLIGQQSTVSDV-PRDLEVVAATPTSLLISWDAPAVTVRYYRIT 1572
                I A+N  G  E   L G       + P ++E+ A     +++   A   T+R +   
Sbjct: 18770 NFRICAINSEGVGEPATLPGSVVAQERIEPPEIELDADLRKVVVLRASA---TLRLFVTI 18826

Query: 1573  YGETGGNSPVQEFTVPGSKSTAT-ISGLKPGVDYTITVYAVTGRGDS---------PASS 1622
              G      P  E     ++   T  + ++    +T+ V     R DS          + S
Sbjct: 18827 KGR-----PEPEVKWEKAEGILTDRAQIEVTSSFTMLVIDNVTRFDSGRYNLTLENNSGS 18881

Query: 1623  KPISINYRTEIDKPS---QMQVTDVQDNSISVKWLP----SSSPVTGYRV---TTTPKNG 1672
             K   +N R  +D PS    + + +V+ +S+++ W P      + +T Y V    TT K  
Sbjct: 18882 KTAFVNVRV-LDSPSAPVNLTIREVKKDSVTLSWEPPLIDGGAKITNYIVEKRETTRK-- 18938

Query: 1673  PGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPK----G 1728
                  T T    +T   IE LQ    Y   V A N  G   P   T    +  P      
Sbjct: 18939 --AYATITNNCTKTTFRIENLQEGCSYYFRVLASNEYGIGLPAETTEPVKVSEPPLPPGR 18996

Query: 1729  LAFTDVDVDSIKIAWESPQ----GQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLR 1784
             +   DV  ++  I WE P+     +++ Y V   +   G  +       +   A + GL 
Sbjct: 18997 VTLVDVTRNTATIKWEKPESDGGSKITGYVVEMQT--KGSEKWSTCTQVKTLEATISGLT 19054

Query: 1785  PGSEYTVSVVALHDDMESQPL-----IGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQ 1839
              G EY   V A+++   S P      +  +   I    +L F   T    + +    +V 
Sbjct: 19055 AGEEYVFRVAAVNEKGRSDPRQLGVPVIARDIEIKPSVELPFH--TFNVKAREQLKIDVP 19112

Query: 1840  LTGYRVRVTPKEKTG-PMKEINLAPDSSSVVVSGLMV--ATKYEVSVYAL--KDTLTSRP 1894
               G         K G  +KE      SSS  V+ L +  A+K +V  Y L   ++  S  
Sbjct: 19113 FKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSNSAGSIT 19172

Query: 1895  AQGVVTTLENVSPPRRARVTDATETTITISWRTKTE----TITGFQVDAVPANGQT---- 1946
                 +  L+   PP   R+ + +  +ITISW          I+ + V+       T    
Sbjct: 19173 VPITIIVLDRPGPPGPIRIDEVSCDSITISWNPPEYDGGCQISNYIVEKKETTSTTWHIV 19232

Query: 1947  --PIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDA-------- 1996
                + RT      S  I  L  G++Y+  +   N   +SS      S+A+ A        
Sbjct: 19233 SQAVART------SIKIVRLTTGSEYQFRVCAENRYGKSS---YSESSAVVAEYPFSPPG 19283

Query: 1997  -PSNLRFLATTPNSLLVSWQPP----RARITGYIIKYEKPGSPPREVVPRPRPGVTEATI 2051
              P   + +  T +++LV+WQ P     +R+ GY ++Y++  S       +     T+  +
Sbjct: 19284 PPGTPKVVHATKSTMLVTWQVPVNDGGSRVIGYHLEYKERSSILWSKANKILIADTQMKV 19343

Query: 2052  TGLEPGT--EYTIY 2063
             +GL+ G   EY +Y
Sbjct: 19344 SGLDEGLMYEYRVY 19357



 Score =  109 bits (273), Expect = 3e-23
 Identities = 290/1404 (20%), Positives = 524/1404 (37%), Gaps = 190/1404 (13%)

Query: 812   DAPPDPT----VDQVDDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETAN 863
             D P  PT    +  + + S+ ++W  P+    + +T Y ++   +     TE++      
Sbjct: 20263 DRPGPPTGPVVISDITEESVTLKWEPPKYDGGSQVTNYILLKRETSTAVWTEVSATVART 20322

Query: 864   SVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFV-EVTDVK 922
              + +  L  G +Y   I A  EN+      I           T P P    +V  VT   
Sbjct: 20323 MMKVMKLTTGEEYQFRIKA--ENRFGISDHIDSACVTVKLPYTTPGPPSTPWVTNVTRES 20380

Query: 923   VTIMWTPPES----AVTGYRVDVIPVN-LPGEHGQRLPISRNTFAEVTGLSPGVTYYFKV 977
             +T+ W  P S    AV GY +++   N +  +   +L I R T  +VT +S G+ Y F+V
Sbjct: 20381 ITVGWHEPVSNGGSAVVGYHLEMKDRNSILWQKANKLVI-RTTHFKVTTISAGLIYEFRV 20439

Query: 978   FAVSHGRESKPL-TAQQTTKLDA---PTNLQFVNETDSTVLVRWTPPR----AQITGYRL 1029
             +A +     KP   ++    +DA   P N++  + + ++V + W  P     ++ITGY  
Sbjct: 20440 YAENAAGVGKPSHPSEPVLAIDACEPPRNVRITDISKNSVSLSWQQPAFDGGSKITGYI- 20498

Query: 1030  TVGLTRRGQP-----RQYNVGPSVSKYPLRNLQPASEYTVSLVA--IKGNQESP-KATGV 1081
                + RR  P     +      + +++ +  L   S+Y   + A    G+  +P +  G 
Sbjct: 20499 ---VERRDLPDGRWTKASFTNVTETQFIISGLTQNSQYEFRVFARNAVGSISNPSEVVGP 20555

Query: 1082  FTTLQ----PGSSIPPYNTEVTE----TTIV----ITWTPAPRI-GFKLGVRPSQGGEAP 1128
              T +     P   +P   TEV +    T++     I+  PAP I  +K            
Sbjct: 20556 ITCIDSYGGPVIDLPLEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVC 20615

Query: 1129  REVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDT 1188
              E T+D  SI++          Y +++        A I  +++    PP           
Sbjct: 20616 VENTTDLASILIKDADRLNSGCYELKLRNAMGSASATIRVQILDKPGPPGGPIEFKTVTA 20675

Query: 1189  GVLTVSWERSTTPD----ITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYN 1244
               +T+ W R    D    IT Y +    T+    + + E  H ++   T   +  G EY 
Sbjct: 20676 EKITLLW-RPPADDGGAKITHYIVEKRETSRVVWSMVSE--HLEECIITTTKIIKGNEYI 20732

Query: 1245  VSVYTVKDDKESVPI-SDTII----------PEVPQLTDLSFVDITDSSIGLRWT-PL-- 1290
               V  V       P+ SD+++          P +P++T      IT +S+ + W+ P+  
Sbjct: 20733 FRVRAVNKYGIGEPLESDSVVAKNAFVTPGPPGIPEVT-----KITKNSMTVVWSRPIAD 20787

Query: 1291  NSSTIIGYRITVVAAGEGIPIFEDFVDSSVGYY------------TVTGLEPGIDYDISV 1338
               S I GY              E     S+G++             VTGL    DY   V
Sbjct: 20788 GGSDISGY------------FLEKRDKKSLGWFKVLKETIRDTRQKVTGLTENSDYQYRV 20835

Query: 1339  ITLINGGE---SAPTTLTQQTAVP-----PPTDLRFTNIGPDTMRVTWAPP---PSIDLT 1387
               +   G+   S P+    + A P     PP  +R  +    ++ + W+ P       +T
Sbjct: 20836 CAVNAAGQGPFSEPSEF-YKAADPIDPPGPPAKIRIADSTKSSITLGWSKPVYDGGSAVT 20894

Query: 1388  NFLVRYSPVKNEE-DVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQ- 1445
              ++V     + EE               V++NL PG  Y   VS+V    +  P+   + 
Sbjct: 20895 GYVVEIRQGEEEEWTTVSTKGEVRTTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEP 20954

Query: 1446  ---KTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRN 1502
                K  L++P  ID       S           +  ++ R  P     +  ++    +R 
Sbjct: 20955 VQAKDILEAPE-IDLDVALRTSVIAKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARY 21013

Query: 1503  SI---------TLTNLTPGT--EYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAAT 1551
             SI         T+  +T     +Y+++I    G  +S  +  +        + L+V   +
Sbjct: 21014 SIENTDSSSLLTIPQVTRNDTGKYILTIENGVGEPKSSTVSVKVLDTPAACQKLQVKHVS 21073

Query: 1552  PTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGL-----KPGVDYT 1606
               ++ + WD P +      I Y     ++  + ++V   K ++T   L     K    + 
Sbjct: 21074 RGTVTLLWDPPLIDGGSPIINYVIEKRDATKRTWSVVSHKCSSTSFKLIDLSEKTPFFFR 21133

Query: 1607  ITVYAVTGRGDSPASSKPISINYRTEIDKP-SQMQVTDVQDNSISVKW----LPSSSPVT 1661
             +      G G+   +++P+      E+  P   + + D    S+ + W        S +T
Sbjct: 21134 VLAENEIGIGEPCETTEPVK---AAEVPAPIRDLSMKDSTKTSVILSWTKPDFDGGSVIT 21190

Query: 1662  GYRVTTTPKNGPGPTKTKTAGPDQT-EMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAV 1720
              Y V    + G G      AG  +T E+ +  L+        V+A+N  G S P+    +
Sbjct: 21191 EYVV---ERKGKGEQTWSHAGISKTCEIEVSQLKEQSVLEFRVFAKNEKGLSDPVTIGPI 21247

Query: 1721  TNIDRPKGLAFT-DVDVDSIKIAWESPQ-GQVSRYRVTY-SSPEDGIHEL---FPAPDGE 1774
             T     K L  T +VD+  I  A  + + G      + Y   P+  I  L    P  + E
Sbjct: 21248 T----VKELIITPEVDLSDIPGAQVTVRIGHNVHLELPYKGKPKPSISWLKDGLPLKESE 21303

Query: 1775  -------EDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPT----DLKFTQ 1823
                    E+   L       E+      + D+   +  +      +  P+     ++F +
Sbjct: 21304 FVRFSKTENKITLSIKNAKKEHGGKYTVILDNAVCRIAVPITVITLGPPSKPKGPIRFDE 21363

Query: 1824  VTPTSLSAQWTPP----NVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKY 1879
             +   S+   W  P      ++T Y +      +T   K +  +   ++  V  L+   +Y
Sbjct: 21364 IKADSVILSWDVPEDNGGGEITCYSIEKRETSQTN-WKMVCSSVARTTFKVPNLVKDAEY 21422

Query: 1880  EVSVYALKDTLTSRPAQGVVTTLEN----VSPPRRARVTDATETTITISWRTKT----ET 1931
             +  V A      S+P    +   ++      PP +  + + T   ++++W          
Sbjct: 21423 QFRVRAENRYGVSQPLVSSIIVAKHQFRIPGPPGKPVIYNVTSDGMSLTWDAPVYDGGSE 21482

Query: 1932  ITGFQVDAVPANGQTPIQRTIKP-DVRSYTITGLQPGTDYKIYLYTLNDNARSSP----V 1986
             +TGF V+    N     +    P   R Y  TGL  G DY+  +Y  N    SSP     
Sbjct: 21483 VTGFHVEKKERNSILWQKVNTSPISGREYRATGLVEGLDYQFRVYAENSAGLSSPSDPSK 21542

Query: 1987  VIDASTAIDAPSNLRFLATTPNSLLVSWQPP----RARITGYIIKYEKPGSPPREVVPRP 2042
                A + +D P    ++  T  ++ + W PP     ++I GY I+ ++ G+         
Sbjct: 21543 FTLAVSPVDPPGTPDYIDVTRETITLKWNPPLRDGGSKIVGYSIE-KRQGNERWVRCNFT 21601

Query: 2043  RPGVTEATITGLEPGTEYTIYVIA 2066
                  + T+TGL PG  Y   +IA
Sbjct: 21602 DVSECQYTVTGLSPGDRYEFRIIA 21625



 Score =  109 bits (272), Expect = 4e-23
 Identities = 299/1423 (21%), Positives = 501/1423 (35%), Gaps = 243/1423 (17%)

Query: 728   VTEITASSFVVSW----VSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPG 783
             +++I A +  +SW          ++ + VE      GD    L    T TS  +  L+PG
Sbjct: 12696 ISDIDADACSLSWHIPLEDGGSNITNYIVEKCDVSRGDWVTAL-ASVTKTSCRVGKLIPG 12754

Query: 784   RKYIVNV-----YQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ--- 835
             ++YI  V     + ISE      +++      P  P +  V +V+   I V W RP    
Sbjct: 12755 QEYIFRVRAENRFGISEPLTSPKMVAQFPFGVPSEPKNARVTKVNKDCIFVAWDRPDSDG 12814

Query: 836   -APITGYRIVYSPS-----VEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQES 889
              +PI GY I          V+ + T +   E       + L  G++Y+  IYA+ +   S
Sbjct: 12815 GSPIIGYLIERKERNSLLWVKANDTLVRSTE----YPCAGLVEGLEYSFRIYALNKAGSS 12870

Query: 890   TPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPVN 945
              P    +  T     D    P   + ++VT   V+++W  P+    S + GY V+     
Sbjct: 12871 PPSKPTEYVTARMPVDPPGKP---EVIDVTKSTVSLIWARPKHDGGSKIIGYFVEA--CK 12925

Query: 946   LPGEHGQRLPISRNTFAE----VTGLSPGVTYYFKVF---AVSHGRESKPLTAQQTTKLD 998
             LPG+   R   + +   +     TGL     Y F+     AV+    S+P         +
Sbjct: 12926 LPGDKWVRCNTAPHQIPQEEYTATGLEEKAQYQFRAIARTAVNISPPSEPSDPVTILAEN 12985

Query: 999   APTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQ----------YNVGPSV 1048
              P  +       S + V+         G  + +  T  G+P                  +
Sbjct: 12986 VPPRIDLSVAMKSLLTVK--------AGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGI 13037

Query: 1049  SKYPLRNL----------QPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEV 1098
                  RNL          + + +YT++     G++ +     V    +PG   PP + ++
Sbjct: 13038 KMAMQRNLCTLELFSVNRKDSGDYTITAENSSGSKSATIKLKVLD--KPG---PPASVKI 13092

Query: 1099  TE---TTIVITWTPAPRIG------FKLGVR-PSQGGEAPREVTSDSGSIVVSGLTPGVE 1148
              +      +++W P    G      + +  R  S+   A    T    S  V  L  G E
Sbjct: 13093 NKMYSDRAMLSWEPPLEDGGSEITNYIVDKRETSRPNWAQVSATVPITSCSVEKLIEGHE 13152

Query: 1149  YVYTIQVLRDGQERDAPIVNKVV--TPLSPPTNLH--LEANPDTGVLTVSWERSTT---P 1201
             Y + I         D       +   P  PP      + +N     +TVSW+        
Sbjct: 13153 YQFRICAENKYGVGDPVFTEPAIAKNPYDPPGRCDPPVISNITKDHMTVSWKPPADDGGS 13212

Query: 1202  DITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTV--------KDD 1253
              ITGY +    T       +      ++ +     L  G EY   V  +         D 
Sbjct: 13213 PITGYLLEKRETQAVNWTKVNRKPIIER-TLKATGLQEGTEYEFRVTAINKAGPGKPSDA 13271

Query: 1254  KESVPISDTIIPEVPQLTDLSFVDITDSSIGLRWTPL---NSSTIIGYRITVVAAGEGIP 1310
              ++    D   P  P      + D T SS+ L W        S IIGY + V  A     
Sbjct: 13272 SKAAYARDPQYPPGPPAFPKVY-DTTRSSVSLSWGKPAYDGGSPIIGYLVEVKRADS--- 13327

Query: 1311  IFEDFVDSSVGY------YTVTGLEPGIDYDISVITLINGGESAPTTL-----TQQTAVP 1359
               +++V  ++        + VTGL     Y   V  +   G S P+ +      +   +P
Sbjct: 13328 --DNWVRCNLPQNLQKTRFEVTGLMEDTQYQFRVYAVNKIGYSDPSDVPDKHYPKDILIP 13385

Query: 1360  P----PTDLRFTNI--GPDTMR----VTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISP 1409
             P      DLR T I     TMR    V   PPP I  +       P  N  D   L I  
Sbjct: 13386 PEGELDADLRKTLILRAGVTMRLYVPVKGRPPPKITWS------KPNVNLRDRIGLDIKS 13439

Query: 1410  SDNAVVL----TNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSF 1465
             +D    L     N     +Y++++ +   + E T +     T    P  +   +I+ +S 
Sbjct: 13440 TDFDTFLRCENVNKYDAGKYILTLENSCGKKEYTIVVKVLDTP-GPPVNVTVKEISKDSA 13498

Query: 1466  TVHWIAP----RATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVA 1521
              V W  P     + I  Y ++                 S+ S  + NL  G  Y   + A
Sbjct: 13499 YVTWEPPIIDGGSPIINYVVQKRDAERKSWSTV-TTECSKTSFRVANLEEGKSYFFRVFA 13557

Query: 1522  LNGREESPLLIGQQSTVSDVPR---------DLEVVAATPTSLLISWDAPAVTVRYYRIT 1572
                  E+   IG      D  +         DL+V + + +S  I W  P        I 
Sbjct: 13558 -----ENEYGIGDPGETRDAVKASQTPGPVVDLKVRSVSKSSCSIGWKKPHSDGGSRIIG 13612

Query: 1573  YGETGGNSPVQEFTVPGSKSTATISGLK---------PGVDYTITVYAVTGRGDSPASSK 1623
             Y        V +F    +K    +  L           G +YT  V A    G+   S  
Sbjct: 13613 Y--------VVDFLTEENKWQRVMKSLSLQYSAKDLTEGKEYTFRVSAENENGEGTPSE- 13663

Query: 1624  PISINYRTEIDKPSQMQVTDVQDNSISVKWLPS----SSPVTGYRVTTTPKNGPGPTKTK 1679
              I++  R ++  P            + +K LP     +   + +R+    K  P P+ + 
Sbjct: 13664 -ITVVARDDVVAP-----------DLDLKGLPDLCYLAKENSNFRLKIPIKGKPAPSVSW 13711

Query: 1680  TAGPD----QTEMTIEGLQPTVEYVV-----------SVYAQNPSGESQPLVQTAVTNID 1724
               G D     T +++E        +V           ++  +N +G  +  +   V    
Sbjct: 13712 KKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKEGTISIKVVGKP 13771

Query: 1725  R-PKG-LAFTDVDVDSIKIAWESPQGQVSRYRVTY-SSPEDGIHELFP--APDGEEDTAE 1779
               P G + F +V  +++ + W  P+         Y     D ++  +   A   ++ T  
Sbjct: 13772 GIPTGPIKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDSVNNKWVTCASAVQKTTFR 13831

Query: 1780  LQGLRPGSEYTVSVVA-----LHDDMESQPLIGTQSTAIP-APTDLKFTQVTPTSLSAQW 1833
             +  L  G EYT  V A     + + ++S+P++      +P AP       V   S+S  W
Sbjct: 13832 VTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVPDAPPPPNIVDVRHDSVSLTW 13891

Query: 1834  TPP----NVQLTGYRVRVTPKEKTGPM-KEINLAP-DSSSVVVSGLMVATKYEVSVYAL- 1886
             T P       +TGY +    KE+   + K  N  P       V+GL    +YE  V A+ 
Sbjct: 13892 TDPKKTGGSPITGYHLEF--KERNSLLWKRANKTPIRMRDFKVTGLTEGLEYEFRVMAIN 13949

Query: 1887  -----KDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKT----ETITGFQV 1937
                  K +L S P    V  L+ + PP +  V + T  ++T+ W          +TG+ V
Sbjct: 13950 LAGVGKPSLPSEP----VVALDPIDPPGKPEVINITRNSVTLIWTEPKYDGGHKLTGYIV 14005

Query: 1938  DA--VPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLN 1978
             +   +P+           P+  ++T+T L  G  Y+  +   N
Sbjct: 14006 EKRDLPSKSWMKANHVNVPEC-AFTVTDLVEGGKYEFRIRAKN 14047



 Score =  108 bits (269), Expect = 8e-23
 Identities = 265/1341 (19%), Positives = 468/1341 (34%), Gaps = 163/1341 (12%)

Query: 780   LLPGRKYIVNVYQISEDGE----QSLILSTSQTTAPDAPPD-PTVDQVDDTSIVVRWSRP 834
             L+ G +YI  V  ++  G+    QS  +       P  PP+ P V  V   +  V W RP
Sbjct: 14231 LIQGNEYIFRVSAVNHYGKGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSWKRP 14290

Query: 835   Q----APITGYRIVYSPSVEGSSTE-LNLPETANSVTLSDLQPGVQYNITIYA-----VE 884
                  + ITGY +             +  P +     ++ LQ G  Y   + A     + 
Sbjct: 14291 VDDGGSEITGYHVERREKKSLRWVRAIKTPVSDLRCKVTGLQEGSTYEFRVSAENRAGIG 14350

Query: 885   ENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPES----AVTGYRVD 940
                E++  V+ ++    P   + P   D      T    ++ W  P       +TGY V+
Sbjct: 14351 PPSEASDSVLMKDAAYPPGPPSNPHVTD-----TTKKSASLAWGKPHYDGGLEITGYVVE 14405

Query: 941   VIPVN----LPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQ--QT 994
                V     +    G  L I++     V  L     Y F++ A++     +P      + 
Sbjct: 14406 HQKVGDEAWIKDTTGTALRITQFV---VPDLQTKEKYNFRISAINDAGVGEPAVIPDVEI 14462

Query: 995   TKLDAPTNLQFVNETDSTVLVR-------WTP----PRAQITGYRLTVGLTRRGQPRQYN 1043
              + +   + +   E   T++VR       + P    P  ++T  +  + L  R       
Sbjct: 14463 VEREMAPDFELDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKNRANIENTE 14522

Query: 1044  VGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTI 1103
                ++   P  N     ++ +++    G +       V  T  P  ++ P  T++T+ ++
Sbjct: 14523 -SFTLLIIPECNRYDTGKFVMTIENPAGKKSGFVNVRVLDTPGPVLNLRP--TDITKDSV 14579

Query: 1104  VITWT-PAPRIGFKLGVRPSQGGEAPREVTSDSGS------IVVSGLTPGVEYVYTIQVL 1156
              + W  P    G ++     +  EA R+  S + +        V+GL+ G EY + +   
Sbjct: 14580 TLHWDLPLIDGGSRITNYIVEKREATRKSYSTATTKCHKCTYKVTGLSEGCEYFFRVMAE 14639

Query: 1157  RD---GQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPD---ITGYRITT 1210
              +   G+  +     K     SPP +L++  +     ++++W +        ITGY I  
Sbjct: 14640 NEYGIGEPTETTEPVKASEAPSPPDSLNI-MDITKSTVSLAWPKPKHDGGSKITGYVIEA 14698

Query: 1211  TPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISD--TIIPEVP 1268
                   Q   +  V   +   C   NL+ G EY   V  V     S P      I+ E  
Sbjct: 14699 QRKGSDQWTHITTVKGLE---CVVRNLTEGEEYTFQVMAVNSAGRSAPRESRPVIVKEQT 14755

Query: 1269  QLTDLSFVDITDSSIGLRWTPLNSSTI--IGYRITVVAAGEGIPI--------FEDFVDS 1318
              L +L    I    +  +        I  +G     V   +G  I        FE    S
Sbjct: 14756 MLPELDLRGIYQKLVIAKAGDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATS 14815

Query: 1319  SVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTW 1378
             ++             Y ++   ++       T        PP   ++F  +  D +  +W
Sbjct: 14816 TILNINECVRSDSGPYPLTARNIVGEVGDVITIQVHDIPGPPTGPIKFDEVSSDFVTFSW 14875

Query: 1379  APPPS---IDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSS---- 1431
              PP +   + ++N++V      +   V EL+ +        T L  G EY   V +    
Sbjct: 14876 DPPENDGGVPISNYVVEMRQTDSTTWV-ELATTVIRTTYKATRLTTGLEYQFRVKAQNRY 14934

Query: 1432  -VYEQHESTPLRGRQKTGLDSPTGI-DFSDITANSFTVHWIAP----RATITGYRIRHHP 1485
              V     S  +       +  P G    + +T +S T+ W  P     + I GY +    
Sbjct: 14935 GVGPGITSACIVANYPFKVPGPPGTPQVTAVTKDSMTISWHEPLSDGGSPILGYHVERKE 14994

Query: 1486  EHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN-------GREESPLLIGQQSTV 1538
              +        +     N    + LT G  Y   ++A N        +   P+L       
Sbjct: 14995 RNGILWQTVSKALVPGNIFKSSGLTDGIAYEFRVIAENMAGKSKPSKPSEPMLALDPIDP 15054

Query: 1539  SDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPG----SKSTA 1594
                P  L +   T T   + W  P  T  +   +Y     + P   +         ++  
Sbjct: 15055 PGKPVPLNITRHTVT---LKWAKPEYTGGFKITSYIVEKRDLPNGRWLKANFSNILENEF 15111

Query: 1595  TISGLKPGVDYTITVYAVTGRGD-SPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKW 1653
             T+SGL     Y   V A    G  SP S    +I  R +++ P        +D  I    
Sbjct: 15112 TVSGLTEDAAYEFRVIAKNAAGAISPPSEPSDAITCRDDVEAPKIKVDVKFKDTVI---- 15167

Query: 1654  LPSSSPVTGYRVTTTPKNGPGPTK------TKTAGPDQTEMTIEGLQPTV---------E 1698
                      +R+       P PT        +  G  + E+ I      +          
Sbjct: 15168 ---LKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDS 15224

Query: 1699  YVVSVYAQNPSGESQPLVQTAVTNIDRP----KGLAFTDVDVDSIKIAWESP---QGQVS 1751
                ++ A NP G ++ +    V  +DRP      LA T+V  +   ++W  P    G   
Sbjct: 15225 GAYTLTATNPGGFAKHIFNVKV--LDRPGPPEGPLAVTEVTSEKCVLSWFPPLDDGGAKI 15282

Query: 1752  RYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALH-----DDMESQPLI 1806
              + +        +     A + +    ++  L  G+EY   V+A++     + +ES+P++
Sbjct: 15283 DHYIVQKRETSRLAWTNVASEVQVTKLKVTKLLKGNEYIFRVMAVNKYGVGEPLESEPVL 15342

Query: 1807  GTQSTAIP-APTDLKFTQVTPTSLSAQWTPPN----VQLTGYRVRVTPKEKTGPMKEINL 1861
                    P  P + + T +T  S+   W  P+     ++  Y V    K     +K    
Sbjct: 15343 AVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEIINYIVERRDKAGQRWIKCNKK 15402

Query: 1862  APDSSSVVVSGLMVATKYEVSVYA-----LKDTLTSRPAQGVVTTLENVSPPRRARVTDA 1916
                     VSGL    +YE  + A     +     + P      T+    PP   RV D 
Sbjct: 15403 TLTDLRYKVSGLTEGHEYEFRIMAENAAGISAPSPTSPFYKACDTVFKPGPPGNPRVLDT 15462

Query: 1917  TETTITISWRTKT----ETITGFQVD-AVPANGQTPIQRTIKP----DVRSYTITGLQPG 1967
             + ++I+I+W          ITG+ V+ A+P   +  I   + P       SYTITGL   
Sbjct: 15463 SRSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQI---VTPPAGLKATSYTITGLTEN 15519

Query: 1968  TDYKIYLYTLNDNARSSPVVI 1988
              +YKI +Y +N      P ++
Sbjct: 15520 QEYKIRIYAMNSEGLGEPALV 15540



 Score =  107 bits (268), Expect = 1e-22
 Identities = 324/1575 (20%), Positives = 574/1575 (36%), Gaps = 187/1575 (11%)

Query: 552   RWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCY-----GRGIGEWHCQPLQTYP 606
             RWK    D  +    G  Y++       + G  YQ   Y     G G       P     
Sbjct: 10057 RWKRVNRDPIKAMTLGVSYKVTG----LIEGSDYQFRVYAINAAGVGPASLPSDPATARD 10112

Query: 607   SSSGPVEVFITETPSQPNSHPIQWNAPQP---SHISKYILRWRP--KNSVGRWKEATIPG 661
               + P   F   T    +S  ++W+ P     S ++ YI+ ++   K    + K+  + G
Sbjct: 10113 PIAPPGPPFPKVTDWTKSSADLEWSPPLKDGGSKVTGYIVEYKEEGKEEWEKGKDKEVRG 10172

Query: 662   HLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPL 721
                   + GLK G  Y+ ++ ++   G  E              + S  +  + +    +
Sbjct: 10173 --TKLVVTGLKEGAFYKFRVRAVNIAGIGEPGEVT-DVIEMKDRLVSPDLQLDASVRDRI 10229

Query: 722   VATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTA--TSVNIPD 779
             V  +  V  I      +++VS     +   V + ++E    PQ   + +TA  +S+ I +
Sbjct: 10230 VVHAGGVIRI------IAYVSGKPPPT---VTWNMNER-TLPQEATIETTAISSSMVIKN 10279

Query: 780   LLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTV-DQVDDTSIVVRWSRPQ--- 835
                  + + ++   +E GE+   +       P     P +   + + S  + W  P+   
Sbjct: 10280 CQRSHQGVYSLLAKNEAGERKKTIIVDVLDVPGPVGTPFLAHNLTNESCKLTWFSPEDDG 10339

Query: 836   -APITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVI 894
              +PIT Y I    S   + T +    T  + T+  L  G  Y   I A E +    P V 
Sbjct: 10340 GSPITNYVIEKRESDRRAWTPVTYTVTRQNATVQGLIQGKAYFFRI-AAENSIGMGPFVE 10398

Query: 895   QQETTGTPRSDTVPS-PRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPVNLPGE 949
               E        TVP  P DL+  EVT   VT+ W PP+    S +  Y   V+   L G 
Sbjct: 10399 TSEALVIREPITVPERPEDLEVKEVTKNTVTLTWNPPKYDGGSEIINY---VLESRLIGT 10455

Query: 950   HGQRLPISRNTFAE---VTGLSPGVTYYFKVFAVS---HGRES---KPLT-----AQQTT 995
                    + N  +    V GL  G TY ++V AV+    G+ S   KP+T     A  T 
Sbjct: 10456 EKFHKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGKPSFCTKPITCKDELAPPTL 10515

Query: 996   KLDAPTNLQF-VNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLR 1054
              LD    L   V E  +        P+ +++ ++    +    +        +++   ++
Sbjct: 10516 HLDFRDKLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATLALEKIK 10575

Query: 1055  -NLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYN-TEVTETTIVITWTP--- 1109
                  + +Y V +    G+++      V    +PG  + P +  EVT+  +VI+W P   
Sbjct: 10576 AKRSDSGKYCVVVENSTGSRKGFCQVNVVD--RPGPPVGPVSFDEVTKDYMVISWKPPLD 10633

Query: 1110  --APRIGFKLGVRPSQGGEAPREVTSDSGSIV--VSGLTPGVEYVYTIQV-----LRDGQ 1160
                 +I   +  +   G +    VTS S      VS L  G +Y++ I       + D  
Sbjct: 10634 DGGSKITNYIIEKKEVGKDVWMPVTSASAKTTCKVSKLLEGKDYIFRIHAENLYGISDPL 10693

Query: 1161  ERDA-PIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGN 1219
               D+    ++   P +P   +  E   D+ ++T +        IT Y +    T  ++  
Sbjct: 10694 VSDSMKAKDRFRVPDAPDQPIVTEVTKDSALVTWNKPHDGGKPITNYILEKRETMSKRWA 10753

Query: 1220  SLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKD------DKESVPI--SDTIIPEVPQLT 1271
              + +      +     +L  G +Y   V    +         S P+   D I    P + 
Sbjct: 10754 RVTKDPIHPYTKFRVPDLLEGCQYEFRVSAENEIGIGDPSPPSKPVFAKDPIAKPSPPVN 10813

Query: 1272  DLSFVDITDSSIGLRWTPL---NSSTIIGYRITVVAAGEGIPIFEDFVDSSV--GYYTVT 1326
                 +D T +S+ L W P      S I+GY +     G+      +    S     Y VT
Sbjct: 10814 P-EAIDTTCNSVDLTWQPPRHDGGSKILGYIVEYQKVGDEEWRRANHTPESCPETKYKVT 10872

Query: 1327  GLEPGIDYDISVITLINGGESAPTTLTQQTAV----PPPTDLRFTNIG-------PDTMR 1375
             GL  G  Y   V+ +   GES P  + +   V     PP  +   N+         DT+R
Sbjct: 10873 GLRDGQTYKFRVLAVNAAGESDPAHVPEPVLVKDRLEPPELILDANMAREQHIKVGDTLR 10932

Query: 1376  ----VTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLL--PGTEYVVSV 1429
                 +   P P +       R +P K     A + ++P  + + + N     G  Y ++V
Sbjct: 10933 LSAIIKGVPFPKVTWKK-EDRDAPTK-----ARIDVTPVGSKLEIRNAAHEDGGIYSLTV 10986

Query: 1430  SS-VYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAP----RATITGYRIRHH 1484
              +    +  S  +    K G   P  ++ S+I  +S  + W  P     + IT Y +   
Sbjct: 10987 ENPAGSKTVSVKVLVLDKPG--PPRDLEVSEIRKDSCYLTWKEPLDDGGSVITNYVVERR 11044

Query: 1485  PEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVS----- 1539
              +  S +         + S    +L  G +Y+  + A N     P +   +   +     
Sbjct: 11045 -DVASAQWSPLSATSKKKSHFAKHLNEGNQYLFRVAAENQYGRGPFVETPKPIKALDPLH 11103

Query: 1540  --DVPRDLEVVAATPTSLLISWDAP----AVTVRYYRITYGETGGNSPVQEFTVPGSKST 1593
                 P+DL  V    T + + W+ P       +  Y + Y E G    ++  TV  +   
Sbjct: 11104 PPGPPKDLHHVDVDKTEVSLVWNKPDRDGGSPITGYLVEYQEEGTQDWIKFKTV--TNLE 11161

Query: 1594  ATISGLKPGVDYTITVYA--VTGRGDSPASSKPISINYR-----TEIDKPSQMQVTDVQD 1646
               ++GL+ G  Y   V A  + G G  P ++ PI    +      E+D      +     
Sbjct: 11162 CVVTGLQQGKTYRFRVKAENIVGLG-LPDTTIPIECQEKLVPPSVELDVKLIEGLVVKAG 11220

Query: 1647  NSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTE-----MTIEGL--QPTVEY 1699
              ++    +    PV   + TT         KT      +T+     +TI+    + T EY
Sbjct: 11221 TTVRFPAIIRGVPVPTAKWTTDGSE----IKTDEHYTVETDNFSSVLTIKNCLRRDTGEY 11276

Query: 1700  VVSVYAQNPSGESQPLVQTAVTNIDRPK--GLAFTDVDVDSIKIAWESPQGQVSRYRVTY 1757
              ++V   N +G     V   V ++  P    +   DV  + + I+W+ P+       + Y
Sbjct: 11277 QITV--SNAAGSKTVAVHLTVLDVPGPPTGPINILDVTPEHMTISWQPPKDDGGSPVINY 11334

Query: 1758  -SSPEDGIHELFPAPDGEEDTAELQ--GLRPGSEYTVSV-----VALHDDMESQPLIGTQ 1809
                 +D   + +          +L+   L+ G EY   V     + +   ++S P +   
Sbjct: 11335 IVEKQDTRKDTWGVVSSGSSKTKLKIPHLQKGCEYVFRVRAENKIGVGPPLDSTPTVAKH 11394

Query: 1810  STAIPAPTDLK-FTQVTPTSLSAQWTPPNVQ----LTGYRVRVTPKEKTGPMKEINLAPD 1864
               + P+P      T +T  + +  WT P       +TGY +    +E TG    +N  P 
Sbjct: 11395 KFSPPSPPGKPVVTDITENAATVSWTLPKSDGGSPITGYYME--RREVTGKWVRVNKTPI 11452

Query: 1865  SS-SVVVSGLMVATKYEVSVYALKDTLTSRPAQG-----VVTTLENVSPPRRARVTDATE 1918
             +     V+GL     YE  V+A      S+P+           ++   PP   ++ D + 
Sbjct: 11453 ADLKFRVTGLYEGNTYEFRVFAENLAGLSKPSPSSDPIKACRPIKPPGPPINPKLKDKSR 11512

Query: 1919  TTITISWRTKT-----ETITGFQVDAVPANGQTPIQRTIKPDV---RSYTITGLQPGTDY 1970
              T  + W TK        I G+ V+     G     R  K ++    ++ + GL  G +Y
Sbjct: 11513 ETADLVW-TKPLSDGGSPILGYVVEC-QKPGTAQWNRINKDELIRQCAFRVPGLIEGNEY 11570

Query: 1971  KIYLYTLNDNARSSP 1985
             +  +   N      P
Sbjct: 11571 RFRIKAANIVGEGEP 11585



 Score =  106 bits (265), Expect = 2e-22
 Identities = 320/1538 (20%), Positives = 543/1538 (35%), Gaps = 226/1538 (14%)

Query: 702   TSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSW----VSASDTVSGFRVEYELS 757
             T  P  S  V  +T    P       VT+++     V W         +++G+ +E    
Sbjct: 12073 TGPPTESKPVIAKTKYDKPGRPDPPEVTKVSKEEMTVVWNPPEYDGGKSITGYFLE---K 12129

Query: 758   EEGDEPQYLDLPSTATS---VNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDA- 813
             +E    +++ +  +A     + + +LLP  +Y   V   +E G     L +    A D  
Sbjct: 12130 KEKHSTRWVPVNKSAIPERRMKVQNLLPDHEYQFRVKAENEIGIGEPSLPSRPVVAKDPI 12189

Query: 814   --PPDPTVDQVDDT---SIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANS 864
               P  PT  +V DT   SI + W +P     API GY +   P +  +S +        +
Sbjct: 12190 EPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAPIIGYVVEMRPKIADASPDEGWKRCNAA 12249

Query: 865   VTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGT------------------PRSDT 906
               L      V+   T+ +++ENQE    V  Q   G                   P  D 
Sbjct: 12250 AQL------VRKEFTVTSLDENQEYEFRVCAQNQVGIGRPAELKEAIKPKEILEPPEIDL 12303

Query: 907   VPSPRDLQFVEV-TDVKV-TIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEV 964
               S R L  V     +++  I+   P   VT  +V +  V      GQ   +    F  +
Sbjct: 12304 DASMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVV---RKGQVDLVDTMAFLVI 12360

Query: 965   TGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAP-TNLQFVNETDSTVLVRWTPPR-- 1021
                +   +  + +  V+   E       +      P ++L+  + T ++  V W PP   
Sbjct: 12361 PNSTRDDSGKYSLTLVNPAGEKAVFVNVRVLDTPGPVSDLKVSDVTKTSCHVSWAPPEND 12420

Query: 1022  --AQITGYRLTVGLTRRGQPRQYNVGPSVSK--YPLRNLQPASEYTVSLVAIKGNQESPK 1077
               +Q+T Y   V      +     V P V K  + + NL P +EY   + A+  N+  P 
Sbjct: 12421 GGSQVTHY--IVEKREADRKTWSTVTPEVKKTSFHVTNLVPGNEYYFRVTAV--NEYGPG 12476

Query: 1078  ATG-----VFTTLQPGSSIPPYNTEVTETT---IVITWTPAPRIG-FKLG--VRPSQGGE 1126
                     V  +       PP   EVTE T     + W P  R G  K+   +   +  E
Sbjct: 12477 VPTDVPKPVLASDPLSEPDPPRKLEVTEMTKNSATLAWLPPLRDGGAKIDGYITSYREEE 12536

Query: 1127  APREVTSDSG-----SIVVSGLTPGVEYVYTI---QVLRDGQERDAPIVNKVVTPLSPPT 1178
              P +  ++       S+VV+GL  G +Y + +     +     R+A  V +    L PP 
Sbjct: 12537 QPADRWTEYSVVKDLSLVVTGLKEGKKYKFRVAARNAVGVSLPREAEGVYEAKEQLLPPK 12596

Query: 1179  NL-----------------HLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSL 1221
              L                 H+   P     T  W++     +T   +     +      +
Sbjct: 12597 ILMPEQITIKAGKKLRIEAHVYGKPHP---TCKWKKGEDEVVTSSHLAVHKADSSSILII 12653

Query: 1222  EEVVHADQS--SCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPEVPQLTDLSFVDIT 1279
             ++V   D    S T +N S               K  V + D   P  P   D+S  DI 
Sbjct: 12654 KDVTRKDSGYYSLTAENSSG----------TDTQKIKVVVMDAPGPPQPPF-DIS--DID 12700

Query: 1280  DSSIGLRW-TPLNS--STIIGYRITV--VAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDY 1334
               +  L W  PL    S I  Y +    V+ G+ +        +S     V  L PG +Y
Sbjct: 12701 ADACSLSWHIPLEDGGSNITNYIVEKCDVSRGDWVTALASVTKTSC---RVGKLIPGQEY 12757

Query: 1335  DISVITLINGGESAPTTLTQQTAVPP------PTDLRFTNIGPDTMRVTWAPPPSIDLTN 1388
                V      G S P T  +  A  P      P + R T +  D + V W  P S D  +
Sbjct: 12758 IFRVRAENRFGISEPLTSPKMVAQFPFGVPSEPKNARVTKVNKDCIFVAWDRPDS-DGGS 12816

Query: 1389  FLVRYSPVKNEEDVAELSISPSDNAVVLTN-----LLPGTEYVVSVSSVYEQHESTPLRG 1443
              ++ Y  ++ +E  + L +  +D  V  T      L+ G EY   + ++ +   S P + 
Sbjct: 12817 PIIGYL-IERKERNSLLWVKANDTLVRSTEYPCAGLVEGLEYSFRIYALNKAGSSPPSKP 12875

Query: 1444  RQ----KTGLDSPTGIDFSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPRED 1495
              +    +  +D P   +  D+T ++ ++ W  P+    + I GY +           R +
Sbjct: 12876 TEYVTARMPVDPPGKPEVIDVTKSTVSLIWARPKHDGGSKIIGYFVEACKLPGDKWVRCN 12935

Query: 1496  RVPHS--RNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTV---SDVPRDLEVVAA 1550
               PH   +   T T L    +Y    +A      SP             +VP  +++  A
Sbjct: 12936 TAPHQIPQEEYTATGLEEKAQYQFRAIARTAVNISPPSEPSDPVTILAENVPPRIDLSVA 12995

Query: 1551  TPTSLLIS------WDAPAVTVRYYRITYGETGGN-SPVQEFTVPGSKSTATIS----GL 1599
               + L +        DA         +++ + G    P +   +   ++  T+       
Sbjct: 12996 MKSLLTVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNR 13055

Query: 1600  KPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLP---- 1655
             K   DYTIT         S + S  I +    +   P+ +++  +  +   + W P    
Sbjct: 13056 KDSGDYTITA-----ENSSGSKSATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLED 13110

Query: 1656  SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPL 1715
               S +T Y V     + P   +     P  T  ++E L    EY   + A+N  G   P+
Sbjct: 13111 GGSEITNYIVDKRETSRPNWAQVSATVPI-TSCSVEKLIEGHEYQFRICAENKYGVGDPV 13169

Query: 1716  -VQTAVT-NIDRPKGLA----FTDVDVDSIKIAWESPQGQ----VSRYRVTYSSPEDGIH 1765
               + A+  N   P G       +++  D + ++W+ P       ++ Y +     +    
Sbjct: 13170 FTEPAIAKNPYDPPGRCDPPVISNITKDHMTVSWKPPADDGGSPITGYLLEKRETQAVNW 13229

Query: 1766  ELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAI------PAPTDL 1819
                      E T +  GL+ G+EY   V A++     +P   +++         P P   
Sbjct: 13230 TKVNRKPIIERTLKATGLQEGTEYEFRVTAINKAGPGKPSDASKAAYARDPQYPPGPPAF 13289

Query: 1820  -KFTQVTPTSLSAQWTPPNVQ----LTGYRVRVTPKEKTGPMKEINLAPD--SSSVVVSG 1872
              K    T +S+S  W  P       + GY V V   +    ++  NL  +   +   V+G
Sbjct: 13290 PKVYDTTRSSVSLSWGKPAYDGGSPIIGYLVEVKRADSDNWVR-CNLPQNLQKTRFEVTG 13348

Query: 1873  LMVATKYEVSVYALKDTLTSRPAQ--GVVTTLENVSPPRRARVTDATETTITISWRTKTE 1930
             LM  T+Y+  VYA+     S P+         + + PP      D  +T I  +  T   
Sbjct: 13349 LMEDTQYQFRVYAVNKIGYSDPSDVPDKHYPKDILIPPEGELDADLRKTLILRAGVTMRL 13408

Query: 1931  TITGFQVDAVPANGQTPIQRT-IKPDVRSYTITGLQ-PGTDYKIYLYTLNDN-------- 1980
                      VP  G+ P + T  KP+V      GL    TD+  +L   N N        
Sbjct: 13409 --------YVPVKGRPPPKITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKYI 13460

Query: 1981  --------ARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPP----RARITGYIIKY 2028
                      +   +V+        P N+     + +S  V+W+PP     + I  Y+++ 
Sbjct: 13461 LTLENSCGKKEYTIVVKVLDTPGPPVNVTVKEISKDSAYVTWEPPIIDGGSPIINYVVQK 13520

Query: 2029  EKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIA 2066
                       V       T   +  LE G  Y   V A
Sbjct: 13521 RDAERKSWSTV-TTECSKTSFRVANLEEGKSYFFRVFA 13557



 Score =  102 bits (255), Expect = 3e-21
 Identities = 297/1362 (21%), Positives = 483/1362 (35%), Gaps = 240/1362 (17%)

Query: 908   PSP-RDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTG 966
             P P R+L+ V+V+  + T+ W PPE    G  +     N   E  +   +  +T++  T 
Sbjct: 11992 PGPVRNLKIVDVSSDRCTVCWDPPEDD-GGCEIQ----NYILEKCETKRMVWSTYS-ATV 12045

Query: 967   LSPGVT---------YYFKVFAVSH-----GRESKPLTAQQTTKLDAP-----TNLQFVN 1007
             L+PG T         Y F+V A +        ESKP+ A+  TK D P       +  V+
Sbjct: 12046 LTPGTTVTRLIEGNEYIFRVRAENKIGTGPPTESKPVIAK--TKYDKPGRPDPPEVTKVS 12103

Query: 1008  ETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSV---SKYPLRNLQPAS 1060
             + + TV+  W PP       ITGY L      +   R   V  S     +  ++NL P  
Sbjct: 12104 KEEMTVV--WNPPEYDGGKSITGYFLEK--KEKHSTRWVPVNKSAIPERRMKVQNLLPDH 12159

Query: 1061  EYTVSLVAIK----GNQESPKATGVFTT-LQPGSSIPPYNTEVTETT---IVITWTP--- 1109
             EY   + A      G    P    V    ++P    PP N  V +TT   I + W     
Sbjct: 12160 EYQFRVKAENEIGIGEPSLPSRPVVAKDPIEPPG--PPTNFRVVDTTKHSITLGWGKPVY 12217

Query: 1110  ---APRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPI 1166
                AP IG+ + +RP     +P     D G    +     V   +T+  L + QE +  +
Sbjct: 12218 DGGAPIIGYVVEMRPKIADASP-----DEGWKRCNAAAQLVRKEFTVTSLDENQEYEFRV 12272

Query: 1167  VNKVVTPLSPPTNLHLEANP-----------DTGVLTVSWERSTTPD--ITGYRITTTPT 1213
               +    +  P  L     P           D  +  +   R+  P       R    P 
Sbjct: 12273 CAQNQVGIGRPAELKEAIKPKEILEPPEIDLDASMRKLVIVRAGCPIRLFAIVRGRPAPK 12332

Query: 1214  NGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDD-------------KESVPIS 1260
                +   ++ VV   Q      +L   + + V   + +DD             +++V ++
Sbjct: 12333 VTWRKVGIDNVVRKGQV-----DLVDTMAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFVN 12387

Query: 1261  DTIIPEVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGYRIT--VVAAGEGIPIFEDFVDS 1318
               ++     ++DL   D+T +S  + W P  +    G ++T  +V   E        V  
Sbjct: 12388 VRVLDTPGPVSDLKVSDVTKTSCHVSWAPPENDG--GSQVTHYIVEKREADRKTWSTVTP 12445

Query: 1319  SVGY--YTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAVP-------PPTDLRFTNI 1369
              V    + VT L PG +Y   V  +   G   PT + +            PP  L  T +
Sbjct: 12446 EVKKTSFHVTNLVPGNEYYFRVTAVNEYGPGVPTDVPKPVLASDPLSEPDPPRKLEVTEM 12505

Query: 1370  GPDTMRVTWAPP---PSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYV 1426
               ++  + W PP       +  ++  Y   +   D         D ++V+T L  G +Y 
Sbjct: 12506 TKNSATLAWLPPLRDGGAKIDGYITSYREEEQPADRWTEYSVVKDLSLVVTGLKEGKKYK 12565

Query: 1427  VSVSSVYEQHESTPLRGR----QKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIR 1482
               V++      S P         K  L  P  +    IT  +             G ++R
Sbjct: 12566 FRVAARNAVGVSLPREAEGVYEAKEQLLPPKILMPEQITIKA-------------GKKLR 12612

Query: 1483  HHPEHFSGRPR--------EDRV----------PHSRNSITLTNLTPGTEYVVSIVALNG 1524
                 H  G+P         ED V            S + + + ++T       S+ A N 
Sbjct: 12613 IEA-HVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGYYSLTAENS 12671

Query: 1525  R----EESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAP----AVTVRYYRITYGET 1576
                  ++  +++         P D+  + A   SL  SW  P       +  Y +   + 
Sbjct: 12672 SGTDTQKIKVVVMDAPGPPQPPFDISDIDADACSL--SWHIPLEDGGSNITNYIVEKCDV 12729

Query: 1577  GGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDS-PASSKPISINYRTEI-D 1634
                  V       +K++  +  L PG +Y   V A    G S P +S  +   +   +  
Sbjct: 12730 SRGDWVTALASV-TKTSCRVGKLIPGQEYIFRVRAENRFGISEPLTSPKMVAQFPFGVPS 12788

Query: 1635  KPSQMQVTDVQDNSISVKW-LPSS---SPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTI 1690
             +P   +VT V  + I V W  P S   SP+ GY +    +N     K        TE   
Sbjct: 12789 EPKNARVTKVNKDCIFVAWDRPDSDGGSPIIGYLIERKERNSLLWVKANDTLVRSTEYPC 12848

Query: 1691  EGLQPTVEYVVSVYAQNPSGESQPLVQTAVTN----IDRPKGLAFTDVDVDSIKIAWESP 1746
              GL   +EY   +YA N +G S P   T        +D P      DV   ++ + W  P
Sbjct: 12849 AGLVEGLEYSFRIYALNKAGSSPPSKPTEYVTARMPVDPPGKPEVIDVTKSTVSLIWARP 12908

Query: 1747  QGQVSRYRVTY-----SSPEDGIHELFPAPDG---EEDTAELQGLRPGSEYTVSVVALHD 1798
             +       + Y       P D       AP     EE TA   GL   ++Y    +A   
Sbjct: 12909 KHDGGSKIIGYFVEACKLPGDKWVRCNTAPHQIPQEEYTAT--GLEEKAQYQFRAIARTA 12966

Query: 1799  DMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLT-GYRVRVTPKEKTG--- 1854
                S P           P+D       P ++ A+  PP + L+   +  +T K  T    
Sbjct: 12967 VNISPP---------SEPSD-------PVTILAENVPPRIDLSVAMKSLLTVKAGTNVCL 13010

Query: 1855  -------PMKEINLAPDSSSVV-VSGLMVATKYEVSVYAL-----KD----TLTSRPAQG 1897
                    PM  ++   D + +    G+ +A +  +    L     KD    T+T+  + G
Sbjct: 13011 DATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTITAENSSG 13070

Query: 1898  V------VTTLENVSPPRRARVTDATETTITISWRTKTET----ITGFQVDAVPANGQTP 1947
                    +  L+   PP   ++         +SW    E     IT + VD    +    
Sbjct: 13071 SKSATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYIVDKRETSRPNW 13130

Query: 1948  IQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTA---IDAPSNLR--- 2001
              Q +    + S ++  L  G +Y+  +   N      PV  + + A    D P       
Sbjct: 13131 AQVSATVPITSCSVEKLIEGHEYQFRICAENKYGVGDPVFTEPAIAKNPYDPPGRCDPPV 13190

Query: 2002  FLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREVVPRPRPGVTEATI--TGLE 2055
                 T + + VSW+PP     + ITGY++  EK  +         R  + E T+  TGL+
Sbjct: 13191 ISNITKDHMTVSWKPPADDGGSPITGYLL--EKRETQAVNWTKVNRKPIIERTLKATGLQ 13248

Query: 2056  PGTEYTIYVIALKNNQKSEPLIGRKKTVQKTPFVTHPGYDTG 2097
              GTEY   V A+    K+ P  G+     K  +   P Y  G
Sbjct: 13249 EGTEYEFRVTAI---NKAGP--GKPSDASKAAYARDPQYPPG 13285



 Score =  102 bits (255), Expect = 3e-21
 Identities = 274/1373 (19%), Positives = 474/1373 (34%), Gaps = 187/1373 (13%)

Query: 766   LDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDT 825
             +DL  T   + IP+         ++  ++  GE+++ ++      P    D  V  V  T
Sbjct: 12349 VDLVDTMAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFVNVRVLDTPGPVSDLKVSDVTKT 12408

Query: 826   SIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETAN-SVTLSDLQPGVQYNITI 880
             S  V W+ P+    + +T Y IV     +  +     PE    S  +++L PG +Y   +
Sbjct: 12409 SCHVSWAPPENDGGSQVTHY-IVEKREADRKTWSTVTPEVKKTSFHVTNLVPGNEYYFRV 12467

Query: 881   YAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTG 936
              AV E     P  + +    +        PR L+  E+T    T+ W PP     + + G
Sbjct: 12468 TAVNEYGPGVPTDVPKPVLASDPLSEPDPPRKLEVTEMTKNSATLAWLPPLRDGGAKIDG 12527

Query: 937   YRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTK 996
             Y         P +      + ++    VTGL  G  Y F+V             A+    
Sbjct: 12528 YITSYREEEQPADRWTEYSVVKDLSLVVTGLKEGKKYKFRV------------AARNAVG 12575

Query: 997   LDAPTNLQFVNETDSTVLVRWTPPR----AQIT---GYRLTVGLTRRGQPR--------- 1040
             +  P   + V E    +L    PP+     QIT   G +L +     G+P          
Sbjct: 12576 VSLPREAEGVYEAKEQLL----PPKILMPEQITIKAGKKLRIEAHVYGKPHPTCKWKKGE 12631

Query: 1041  ---------QYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSI 1091
                        +   S S   ++++        SL A   +    +   V     PG   
Sbjct: 12632 DEVVTSSHLAVHKADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPGPPQ 12691

Query: 1092  PPYN-TEVTETTIVITW-TPAPRIGFKL------GVRPSQGGEAPREVTSDSGSIVVSGL 1143
             PP++ +++      ++W  P    G  +          S+G       +    S  V  L
Sbjct: 12692 PPFDISDIDADACSLSWHIPLEDGGSNITNYIVEKCDVSRGDWVTALASVTKTSCRVGKL 12751

Query: 1144  TPGVEYVYTIQVLRDGQERDAPIVNKVV------TPLSPPTNLHLEANPDTGVLTVSWER 1197
              PG EY++ ++        +     K+V       P  P      + N D   + V+W+R
Sbjct: 12752 IPGQEYIFRVRAENRFGISEPLTSPKMVAQFPFGVPSEPKNARVTKVNKD--CIFVAWDR 12809

Query: 1198  STT---PDITGYRITTTPTNGQQG-NSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDD 1253
               +     I GY I     N      + + +V + +  C    L  GLEY+  +Y +   
Sbjct: 12810 PDSDGGSPIIGYLIERKERNSLLWVKANDTLVRSTEYPCA--GLVEGLEYSFRIYALNKA 12867

Query: 1254  KESVPISDTIIPEVPQLTD----LSFVDITDSSIGLRWTPL---NSSTIIGYRITVV--- 1303
               S P   T         D       +D+T S++ L W        S IIGY +      
Sbjct: 12868 GSSPPSKPTEYVTARMPVDPPGKPEVIDVTKSTVSLIWARPKHDGGSKIIGYFVEACKLP 12927

Query: 1304  --------AAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVI--TLIN----GGESAP 1349
                      A   IP  E         YT TGLE    Y    I  T +N       S P
Sbjct: 12928 GDKWVRCNTAPHQIPQEE---------YTATGLEEKAQYQFRAIARTAVNISPPSEPSDP 12978

Query: 1350  TTLTQQTAVPPPTDLRF-----------TNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKN 1398
              T+  +  VPP  DL             TN+  D   V   P P++          P + 
Sbjct: 12979 VTILAEN-VPPRIDLSVAMKSLLTVKAGTNVCLDA-TVFGKPMPTVSWKKDGTLLKPAEG 13036

Query: 1399  EEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHEST-PLRGRQKTGLDSPTGIDF 1457
              +   + ++   +  +   N     +Y ++  +      +T  L+   K G   P  +  
Sbjct: 13037 IKMAMQRNLCTLE--LFSVNRKDSGDYTITAENSSGSKSATIKLKVLDKPG--PPASVKI 13092

Query: 1458  SDITANSFTVHWIAP----RATITGYRIRHHPEHFSGRPREDRVPHS--RNSITLTNLTP 1511
             + + ++   + W  P     + IT Y +    +  + RP   +V  +    S ++  L  
Sbjct: 13093 NKMYSDRAMLSWEPPLEDGGSEITNYIV---DKRETSRPNWAQVSATVPITSCSVEKLIE 13149

Query: 1512  GTEYVVSIVALNGREESPLLIGQQSTVS---DVPR--DLEVVA-ATPTSLLISWDAPA-- 1563
             G EY   I A N       +  + +      D P   D  V++  T   + +SW  PA  
Sbjct: 13150 GHEYQFRICAENKYGVGDPVFTEPAIAKNPYDPPGRCDPPVISNITKDHMTVSWKPPADD 13209

Query: 1564  --VTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRG---DS 1618
                 +  Y +   ET   +  +    P  + T   +GL+ G +Y   V A+   G    S
Sbjct: 13210 GGSPITGYLLEKRETQAVNWTKVNRKPIIERTLKATGLQEGTEYEFRVTAINKAGPGKPS 13269

Query: 1619  PASSKPISINYRTEIDKPSQMQVTDVQDNSISVKW----LPSSSPVTGYRVTTTPKNGPG 1674
              AS    + + +     P+  +V D   +S+S+ W        SP+ GY V     +   
Sbjct: 13270 DASKAAYARDPQYPPGPPAFPKVYDTTRSSVSLSWGKPAYDGGSPIIGYLVEVKRADSDN 13329

Query: 1675  PTKTK-TAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFT- 1732
               +        +T   + GL    +Y   VYA N  G S P   + V +   PK +    
Sbjct: 13330 WVRCNLPQNLQKTRFEVTGLMEDTQYQFRVYAVNKIGYSDP---SDVPDKHYPKDILIPP 13386

Query: 1733  --DVDVDSIKIAWESPQGQVSRY---------RVTYSSPEDGIHELFPAPDGEED----- 1776
               ++D D  K         +  Y         ++T+S P   + +         D     
Sbjct: 13387 EGELDADLRKTLILRAGVTMRLYVPVKGRPPPKITWSKPNVNLRDRIGLDIKSTDFDTFL 13446

Query: 1777  TAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPP 1836
               E        +Y +++       E   ++    T  P P ++   +++  S    W PP
Sbjct: 13447 RCENVNKYDAGKYILTLENSCGKKEYTIVVKVLDTPGP-PVNVTVKEISKDSAYVTWEPP 13505

Query: 1837  NVQ----LTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTS 1892
              +     +  Y V+    E+      +      +S  V+ L     Y   V+A  +    
Sbjct: 13506 IIDGGSPIINYVVQKRDAERKS-WSTVTTECSKTSFRVANLEEGKSYFFRVFAENEYGIG 13564

Query: 1893  RPAQ--GVVTTLENVSPPRRARVTDATETTITISWRTK----TETITGFQVDAVPANGQT 1946
              P +    V   +   P    +V   ++++ +I W+         I G+ VD +    + 
Sbjct: 13565 DPGETRDAVKASQTPGPVVDLKVRSVSKSSCSIGWKKPHSDGGSRIIGYVVDFLTEENKW 13624

Query: 1947  PIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSP--VVIDASTAIDAP 1997
               QR +K     Y+   L  G +Y   +   N+N   +P  + + A   + AP
Sbjct: 13625 --QRVMKSLSLQYSAKDLTEGKEYTFRVSAENENGEGTPSEITVVARDDVVAP 13675



 Score =  102 bits (255), Expect = 3e-21
 Identities = 328/1625 (20%), Positives = 588/1625 (36%), Gaps = 231/1625 (14%)

Query: 609   SGPVEVFITETPSQ----------PNSHPIQWNAPQ---PSHISKYILRWRPKNSVGRWK 655
             SG V V + +TP             +S  + W+ P     S I+ YI+  R       + 
Sbjct: 14552 SGFVNVRVLDTPGPVLNLRPTDITKDSVTLHWDLPLIDGGSRITNYIVEKREATRKS-YS 14610

Query: 656   EATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGET 715
              AT   H  +Y + GL  G  Y  ++++  +YG  E        T T+ PV ++      
Sbjct: 14611 TATTKCHKCTYKVTGLSEGCEYFFRVMAENEYGIGE-------PTETTEPVKASE----- 14658

Query: 716   TPFSPLVATSESVTEITASSFVVSWVS----ASDTVSGFRVEYELSEEGDEPQYLDLPST 771
                +P    S ++ +IT S+  ++W          ++G+ +E +  +  D+  ++     
Sbjct: 14659 ---APSPPDSLNIMDITKSTVSLAWPKPKHDGGSKITGYVIEAQ-RKGSDQWTHITTVKG 14714

Query: 772   ATSVNIPDLLPGRKYIVNVYQISEDG-----EQSLILSTSQTTAPDAPPDPTVDQV---- 822
                V + +L  G +Y   V  ++  G     E   ++   QT  P+        ++    
Sbjct: 14715 LECV-VRNLTEGEEYTFQVMAVNSAGRSAPRESRPVIVKEQTMLPELDLRGIYQKLVIAK 14773

Query: 823   --DDTSIVVR-WSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNIT 879
               D+  + +    RP+  +T  +      +   +  +N   TA S T+ ++   V+ +  
Sbjct: 14774 AGDNIKVEIPVLGRPKPTVTWKK---GDQILKQTQRVNFETTATS-TILNINECVRSDSG 14829

Query: 880   IYAVEENQESTPV--VIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPES----A 933
              Y +        V  VI  +    P   T P    ++F EV+   VT  W PPE+     
Sbjct: 14830 PYPLTARNIVGEVGDVITIQVHDIPGPPTGP----IKFDEVSSDFVTFSWDPPENDGGVP 14885

Query: 934   VTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKV-----FAVSHGRESKP 988
             ++ Y V++   +          + R T+ + T L+ G+ Y F+V     + V  G  S  
Sbjct: 14886 ISNYVVEMRQTDSTTWVELATTVIRTTY-KATRLTTGLEYQFRVKAQNRYGVGPGITSAC 14944

Query: 989   LTAQQTTKLDAPTNL-QFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPS 1047
             + A    K+  P    Q    T  ++ + W  P +   G    +G     + R   +  +
Sbjct: 14945 IVANYPFKVPGPPGTPQVTAVTKDSMTISWHEPLSD--GGSPILGYHVERKERNGILWQT 15002

Query: 1048  VSK-------YPLRNLQPASEYTVSLVA--IKGNQESPKATGVFTTLQP----GSSIPPY 1094
             VSK       +    L     Y   ++A  + G  +  K +     L P    G  +P  
Sbjct: 15003 VSKALVPGNIFKSSGLTDGIAYEFRVIAENMAGKSKPSKPSEPMLALDPIDPPGKPVP-- 15060

Query: 1095  NTEVTETTIVITWT-PAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTI 1153
                +T  T+ + W  P    GFK+     +  + P      +G  + +  +  +E  +T+
Sbjct: 15061 -LNITRHTVTLKWAKPEYTGGFKITSYIVEKRDLP------NGRWLKANFSNILENEFTV 15113

Query: 1154  QVLRDGQERDAPIVNK----VVTPLSPPTNL-----HLEANP--------DTGVLTVSWE 1196
               L +    +  ++ K     ++P S P++       +EA          DT +L     
Sbjct: 15114 SGLTEDAAYEFRVIAKNAAGAISPPSEPSDAITCRDDVEAPKIKVDVKFKDTVILKAGEA 15173

Query: 1197  RSTTPDITGYRITTTPTNGQQGNSLE-------------------EVVHADQSSCTFDNL 1237
                  D++G R   T    + G  LE                   +    D  + T    
Sbjct: 15174 FRLEADVSG-RPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDSGAYTLTAT 15232

Query: 1238  SPGLEYNVSVYTVKDDKESVPISDTIIPEVPQLTDLSFVDITDSSIGLRWTPL--NSSTI 1295
             +PG  +   ++ VK      P      PE P    L+  ++T     L W P   +    
Sbjct: 15233 NPG-GFAKHIFNVKVLDRPGP------PEGP----LAVTEVTSEKCVLSWFPPLDDGGAK 15281

Query: 1296  IGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGG-----ESAPT 1350
             I + I        +       +  V    VT L  G +Y   V+ +   G     ES P 
Sbjct: 15282 IDHYIVQKRETSRLAWTNVASEVQVTKLKVTKLLKGNEYIFRVMAVNKYGVGEPLESEPV 15341

Query: 1351  TLTQQTAVP-PPTDLRFTNIGPDTMRVTWAPPPS---IDLTNFLVRYSPVKNEEDVAELS 1406
                     P PP +   T I  D+M V W  P S    ++ N++V       +  +    
Sbjct: 15342 LAVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEIINYIVERRDKAGQRWIKCNK 15401

Query: 1407  ISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTP------LRGRQKTGLDSPTGID-FSD 1459
              + +D    ++ L  G EY   + +      S P       +         P G     D
Sbjct: 15402 KTLTDLRYKVSGLTEGHEYEFRIMAENAAGISAPSPTSPFYKACDTVFKPGPPGNPRVLD 15461

Query: 1460  ITANSFTVHWIAP----RATITGYRIRHH-PEHFSGRPREDRVPHSRNSITLTNLTPGTE 1514
              + +S ++ W  P     + ITGY +    PE    +           S T+T LT   E
Sbjct: 15462 TSRSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQIVTPPAGLKATSYTITGLTENQE 15521

Query: 1515  YVVSIVALNG-------------REESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDA 1561
             Y + I A+N              + E  +L  +    +D+ + + + A     L +    
Sbjct: 15522 YKIRIYAMNSEGLGEPALVPGTPKAEDRMLPPEIELDADLRKVVTIRACCTLRLFVPIKG 15581

Query: 1562  -PAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPA 1620
              PA  V++ R  +GE+   + ++      S S+ T+  +     +    Y +T    S +
Sbjct: 15582 RPAPEVKWAR-DHGESLDKASIE------STSSYTLLIVGNVNRFDSGKYILTVENSSGS 15634

Query: 1621  SSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLP----SSSPVTGYRVTTTPKNGPGPT 1676
              S  +++        P  ++V +V   S+++ W P      S +  Y V          +
Sbjct: 15635 KSAFVNVRVLDTPGPPQDLKVKEVTKTSVTLTWDPPLLDGGSKIKNYIVEKRESTRKAYS 15694

Query: 1677  KTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPL-VQTAVTNIDRPKG---LAFT 1732
                T    +T   ++ LQ    Y   V A+N  G   P     +V   +RP     +   
Sbjct: 15695 TVAT-NCHKTSWKVDQLQEGCSYYFRVLAENEYGIGLPAETAESVKASERPLPPGKITLM 15753

Query: 1733  DVDVDSIKIAWESPQGQVSRYRVTY--SSPEDGIHELFPAPDGEEDTAELQGLRPGSEYT 1790
             DV  +S+ ++WE P+       + Y       G  +       +   A + GL  G EY+
Sbjct: 15754 DVTRNSVSLSWEKPEHDGGSRILGYIVEMQTKGSDKWATCATVKVTEATITGLIQGEEYS 15813

Query: 1791  VSVVALHDDMESQPL-----IGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRV 1845
               V A ++   S P      +  +   IP    L F   T T L+ +    +V   G   
Sbjct: 15814 FRVSAQNEKGISDPRQLSVPVIAKDLVIPPAFKLLFN--TFTVLAGEDLKVDVPFIGRPT 15871

Query: 1846  -RVTPKEKTGPMKEINLAPDSSSVVVSGLMV--ATKYEVSVYALKDTLTSRPAQGV---- 1898
               VT  +   P+K+       S+   S L +  A + +V  Y +K  LT+   + +    
Sbjct: 15872 PAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVK--LTNSAGEAIETLN 15929

Query: 1899  VTTLENVSPPR-RARVTDATETTITISWRTKT----ETITGFQVDAVPANGQTPIQRTIK 1953
             V  L+   PP    ++ + T  +IT+SW         +I  + V+    +  T   + + 
Sbjct: 15930 VIVLDKPGPPTGPVKMDEVTADSITLSWGPPKYDGGSSINNYIVE--KRDTSTTTWQIVS 15987

Query: 1954  PDVRSYTITG--LQPGTDYKIYL-----YTLNDNARSSPVVIDASTAIDAPSNLRFLA-T 2005
               V   TI    L+ G +Y+  +     Y  +    S P V      +  P     +  +
Sbjct: 15988 ATVARTTIKACRLKTGCEYQFRIAAENRYGKSTYLNSEPTVAQYPFKVPGPPGTPVVTLS 16047

Query: 2006  TPNSLLVSWQPP----RARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYT 2061
             + +S+ V W  P     +R+ GY ++ ++  S     + +     T+   TGLE G EY 
Sbjct: 16048 SRDSMEVQWNEPISDGGSRVIGYHLERKERNSILWVKLNKTPIPQTKFKTTGLEEGVEYE 16107

Query: 2062  IYVIA 2066
               V A
Sbjct: 16108 FRVSA 16112



 Score =  102 bits (255), Expect = 3e-21
 Identities = 306/1554 (19%), Positives = 528/1554 (33%), Gaps = 201/1554 (12%)

Query: 610   GPVEVFITETPSQPNSHPIQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSY 666
             GP E  +  T        + WN P     ++IS YI+  R  + +  W + +      +Y
Sbjct: 18498 GPPEGPLKVTGVTAEKCYLAWNPPLQDGGANISHYIIEKRETSRLS-WTQVSTEVQALNY 18556

Query: 667   TIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSE 726
              +  L PG  Y  +++++ +YG  E             P+ S  VT       P   ++ 
Sbjct: 18557 KVTKLLPGNEYIFRVMAVNKYGIGE-------------PLESGPVTACNPYKPPGPPSTP 18603

Query: 727   SVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDE-----PQYLDLPSTATSVNIPDLL 781
              V+ IT  S VV+W    D   G  +E  + E+ D+      +      T   + +  L 
Sbjct: 18604 EVSAITKDSMVVTWARPVDD-GGTEIEGYILEKRDKEGVRWTKCNKKTLTDLRLRVTGLT 18662

Query: 782   PGRKY-----IVNVYQISEDGEQSLILSTSQTTAPDAPP-DPTVDQVDDTSIVVRWSRP- 834
              G  Y       N   + E  E S+         P  PP +P V     +S+ + WS+P 
Sbjct: 18663 EGHSYEFRVAAENAAGVGEPSEPSVFYRACDALYPPGPPSNPKVTDTSRSSVSLAWSKPI 18722

Query: 835   ---QAPITGYRIVYSPSVEGSSTELNLPE--TANSVTLSDLQPGVQYNITIYAVEENQES 889
                 AP+ GY +    +     T    P        T++ L+   +YN  I A+      
Sbjct: 18723 YDGGAPVKGYVVEVKEAAADEWTTCTPPTGLQGKQFTVTKLKENTEYNFRICAINSEGVG 18782

Query: 890   TPVVIQQETTGTPRSD--TVPSPRDLQFVEVTDVKVTI-----MWTPPESAVTGYRVDVI 942
              P  +        R +   +    DL+ V V     T+     +   PE  V   + + I
Sbjct: 18783 EPATLPGSVVAQERIEPPEIELDADLRKVVVLRASATLRLFVTIKGRPEPEVKWEKAEGI 18842

Query: 943   PVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTN 1002
               +   +       +      VT    G   Y      + G ++  +  +      AP N
Sbjct: 18843 LTD-RAQIEVTSSFTMLVIDNVTRFDSG--RYNLTLENNSGSKTAFVNVRVLDSPSAPVN 18899

Query: 1003  LQFVNETDSTVLVRWTPP----RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQP 1058
             L        +V + W PP     A+IT Y +    T R          + + + + NLQ 
Sbjct: 18900 LTIREVKKDSVTLSWEPPLIDGGAKITNYIVEKRETTRKAYATITNNCTKTTFRIENLQE 18959

Query: 1059  ASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYN------TEVTETTIVITW-TPAP 1111
                Y   ++A   + E        TT     S PP         +VT  T  I W  P  
Sbjct: 18960 GCSYYFRVLA---SNEYGIGLPAETTEPVKVSEPPLPPGRVTLVDVTRNTATIKWEKPES 19016

Query: 1112  RIGFKLG----VRPSQGGEAPREVTS-DSGSIVVSGLTPGVEYVYTIQVLR-----DGQE 1161
               G K+        ++G E     T   +    +SGLT G EYV+ +  +      D ++
Sbjct: 19017 DGGSKITGYVVEMQTKGSEKWSTCTQVKTLEATISGLTAGEEYVFRVAAVNEKGRSDPRQ 19076

Query: 1162  RDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDIT-GYRITTTPTNGQQGNS 1220
                P++ + +  + P   L            V        D+    R   T    + G +
Sbjct: 19077 LGVPVIARDI-EIKPSVELPFH------TFNVKAREQLKIDVPFKGRPQATVNWRKDGQT 19129

Query: 1221  LEEVVHADQSS---CTFDNLSPGLEYNVSVY--TVKDDKESVPISDTII------PEVPQ 1269
             L+E    + SS    T  ++    + +V  Y   V +   S+ +  TII      P  P 
Sbjct: 19130 LKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSNSAGSITVPITIIVLDRPGPPGPI 19189

Query: 1270  LTDLSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIFEDFVDSSVGYYT--VTG 1327
               D    +++  SI + W P            +V   E        V  +V   +  +  
Sbjct: 19190 RID----EVSCDSITISWNPPEYDGGCQISNYIVEKKETTSTTWHIVSQAVARTSIKIVR 19245

Query: 1328  LEPGIDYDISVITLINGGESAPTTLTQQTA------VPPPTDLRFTNIGPDTMRVTWAPP 1381
             L  G +Y   V      G+S+ +  +   A        PP   +  +    TM VTW  P
Sbjct: 19246 LTTGSEYQFRVCAENRYGKSSYSESSAVVAEYPFSPPGPPGTPKVVHATKSTMLVTWQVP 19305

Query: 1382  PSIDLTNFLVRYSPVKNEEDV---AELSISPSDNAVVLTNLLPGTEY--------VVSVS 1430
              +   +  +  +   K    +       I  +D  + ++ L  G  Y        +  + 
Sbjct: 19306 VNDGGSRVIGYHLEYKERSSILWSKANKILIADTQMKVSGLDEGLMYEYRVYAENIAGIG 19365

Query: 1431  SVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPR----ATITGYRIRHHPE 1486
                +  E  P R       D P   + ++IT  S ++ W  P     A ITGY +    E
Sbjct: 19366 KCSKSCEPVPAR----DPCDPPGQPEVTNITRKSVSLKWSKPHYDGGAKITGYIVERR-E 19420

Query: 1487  HFSGRPREDRVPHSRNS-ITLTNLTPGTEYVVSIVALNGREE--------SPLLIGQQST 1537
                GR  +    + + +   +T LT    Y   + A N  +          P+++     
Sbjct: 19421 LPDGRWLKCNYTNIQETYFEVTELTEDQRYEFRVFARNAADSVSEPSESTGPIIVKDDVE 19480

Query: 1538  VSDVPRDLE----VVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKST 1593
                V  D++    +V      L I+ D     +    I++ + G     +  T   S   
Sbjct: 19481 PPRVMMDVKFRDVIVVKAGEVLKINADIAGRPLPV--ISWAKDGIEIEERARTEIISTDN 19538

Query: 1594  ATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKP----SQMQVTDVQDNSI 1649
              T+  +K  +      Y +T +  + A ++ +++N +  +DKP      +++  +     
Sbjct: 19539 HTLLTVKDCIRRDTGQYVLTLK--NVAGTRSVAVNCKV-LDKPGPPAGPLEINGLTAEKC 19595

Query: 1650  SVKW---LPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQ 1706
             S+ W            Y +    +               T   +  L    EY+  V   
Sbjct: 19596 SLSWGRPQEDGGADIDYYIVEKRETSHLAWTICEGELQMTSCKVTKLLKGNEYIFRVTGV 19655

Query: 1707  NPSGESQPLVQTAVTNID------RPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSP 1760
             N  G  +PL   A+  +D       P  L  T V  +S+ + W  P+         Y   
Sbjct: 19656 NKYGVGEPLESVAIKALDPFTVPSPPTSLEITSVTKESMTLCWSRPESDGGSEISGYIIE 19715

Query: 1761  EDGIHELFPAPDGEEDTAELQ----GLRPGSEYTVSVVA-----LHDDMESQPLIGTQST 1811
                 + L      ++   +L+    GLR G EY   V A     L    E+ PLI  +  
Sbjct: 19716 RREKNSLRWVRVNKKPVYDLRVKSTGLREGCEYEYRVYAENAAGLSLPSETSPLIRAEDP 19775

Query: 1812  A-IPA-PTDLKFTQVTPTSLSAQWTPP----NVQLTGYRVRVTPKEKTGPMKEINLAPDS 1865
               +P+ P+  K      T+++  W  P       +TGY V     + T     I  +   
Sbjct: 19776 VFLPSPPSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEYKKSDDTDWKTSIQ-SLRG 19834

Query: 1866  SSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENV----------SPPRRARVTD 1915
             +   +SGL    +Y   V ++     S P+      +             S  R+  +  
Sbjct: 19835 TEYTISGLTTGAEYVFRVKSVNKVGASDPSDSSDPQIAKEREEEPLFDIDSEMRKTLIVK 19894

Query: 1916  A-TETTITISWRTK-----------TETITGFQVDAVPANGQTPIQRTIKPDVRSYTITG 1963
             A    T+T+ +R +           T+  T   VD   +     I+   + D   YT+T 
Sbjct: 19895 AGASFTMTVPFRGRPVPNVLWSKPDTDLRTRAYVDTTDSRTSLTIENANRNDSGKYTLT- 19953

Query: 1964  LQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPP 2017
             +Q              +A S  +V+        P+N+     T  S ++SW  P
Sbjct: 19954 IQNVL-----------SAASLTLVVKVLDTPGPPTNITVQDVTKESAVLSWDVP 19996



 Score =  100 bits (248), Expect = 2e-20
 Identities = 162/726 (22%), Positives = 275/726 (37%), Gaps = 92/726 (12%)

Query: 1268  PQLTDLSFVDITDSSIGLRWTPLN---SSTIIGYRITVVAAGEG--IPIFEDFVDSSVGY 1322
             P    +   +I  +SI + W P      + + GY +    A     +P+ E    S+   
Sbjct: 23529 PPTGPIKIDEIDATSITISWEPPELDGGAPLSGYVVEQRDAHRPGWLPVSESVTRST--- 23585

Query: 1323  YTVTGLEPGIDYDISVITLINGG-----ESAPTTLTQQTAVP-PPTDLRFTNIGPDTMRV 1376
             +  T L  G +Y   V      G     +S          +P PP  L+  ++  D M +
Sbjct: 23586 FKFTRLTEGNEYVFRVAATNRFGIGSYLQSEVIECRSSIRIPGPPETLQIFDVSRDGMTL 23645

Query: 1377  TWAPPPS---IDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVY 1433
             TW PP       +T ++V    V+ +  V    +  +      T L  G EY   V+++ 
Sbjct: 23646 TWYPPEDDGGSQVTGYIVERKEVRADRWVRVNKVPVTMTRYRSTGLTEGLEYEHRVTAIN 23705

Query: 1434  EQHESTPLR-GRQKTGLD------SPTGIDFSDITANSFTVHWIAPR----ATITGYRIR 1482
              +    P R  +    +D       P     +D T  S ++ W  P     + +TGY I 
Sbjct: 23706 ARGSGKPSRPSKPIVAMDPIAPPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIE 23765

Query: 1483  HHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVP 1542
                       + +  P      TLT+L  G EY   ++A N         G     ++VP
Sbjct: 23766 MQKVDQHEWTKCNTTPTKIREYTLTHLPQGAEYRFRVLACNA--------GGPGEPAEVP 23817

Query: 1543  RDLEVVAAT--PTSLLISWDAPAVTVRY---YRITYGETGGNSPVQEFTVPGSKSTATIS 1597
               ++V      P   L       + VR     R+T    G   P+ ++T  G +  +  +
Sbjct: 23818 GTVKVTEMLEYPDYELDERYQEGIFVRQGGVIRLTIPIKGKPFPICKWTKEG-QDISKRA 23876

Query: 1598  GLKPGVDYTITVYAVTGRGDS---------PASSKPISINYRTEIDKPSQ----MQVTDV 1644
              +     +T  V     RGDS             K + I  R  I  P+     ++  D+
Sbjct: 23877 MIATSETHTELVIKEADRGDSGTYDLVLENKCGKKAVYIKVRV-IGSPNSPEGPLEYDDI 23935

Query: 1645  QDNSISVKWLPSS----SPVTGYRVTT--TPKNGPGPTKTKTAGPDQTEMTIEGLQPTVE 1698
             Q  S+ V W P +    + + GY +     PK       ++  G   T + ++GL+  VE
Sbjct: 23936 QVRSVRVSWRPPADDGGADILGYILERREVPKAAWYTIDSRVRG---TSLVVKGLKENVE 23992

Query: 1699  YVVSVYAQNPSGESQPLVQ----TAVTNIDRPKGLA----FTDVDVDSIKIAWESPQGQ- 1749
             Y   V A+N  G S+PL      T  T ++ P+  +      DV   S+ ++W  P+   
Sbjct: 23993 YHFRVSAENQFGISKPLKSEEPVTPKTPLNPPEPPSNPPEVLDVTKSSVSLSWSRPKDDG 24052

Query: 1750  VSRYRVTYSSPEDGIHELFPAPDGEEDTAEL---QGLRPGSEYTVSVVALHD------DM 1800
              SR    Y   ++   + +   +  + T  +    GL P +EY   ++A +D        
Sbjct: 24053 GSRVTGYYIERKETSTDKWVRHNKTQITTTMYTVTGLVPDAEYQFRIIAQNDVGLSETSP 24112

Query: 1801  ESQPLIGTQSTAIPA-PTDLKFTQVTPTSLSAQWTPPNV----QLTGYRVRVTPKEKTGP 1855
              S+P++       P+ P +L+   ++  S++ QW  P      ++ GY V       +  
Sbjct: 24113 ASEPVVCKDPFDKPSQPGELEILSISKDSVTLQWEKPECDGGKEILGYWVEYRQSGDSAW 24172

Query: 1856  MKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRP---AQGVVTTL-ENVSPPRRA 1911
              K            + GL+ AT+YE  V+A  +T  SRP   A  + T L    +P  R 
Sbjct: 24173 KKSNKERIKDKQFTIGGLLEATEYEFRVFAENETGLSRPRRTAMSIKTKLTSGEAPGIRK 24232

Query: 1912  RVTDAT 1917
              + D T
Sbjct: 24233 EMKDVT 24238



 Score = 99.8 bits (247), Expect = 3e-20
 Identities = 244/1107 (22%), Positives = 422/1107 (38%), Gaps = 171/1107 (15%)

Query: 1092 PPYNTEVTET---TIVITWT-PAPRIGFKLGVRPSQGGEAPREV------TSDSGSIVVS 1141
            P  N EVTET    + + W  P    G K+     +  +  R+        ++S    V+
Sbjct: 6787 PVRNLEVTETFDGEVSLAWEEPLTDGGSKIIGYVVERRDIKRKTWVLATDRAESCEFTVT 6846

Query: 1142 GLTPG-VEYVYTIQVLR-----DGQERDAPIV--NKVVTPLSPPTNLHLEANPDTGVLTV 1193
            GL  G VEY++ +         +  E D P+   +K   P  PP N+ +      GV ++
Sbjct: 6847 GLQKGGVEYLFRVSARNRVGTGEPVETDNPVEARSKYDVP-GPPLNVTITDVNRFGV-SL 6904

Query: 1194 SWERSTTP---DITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYT- 1249
            +WE        +IT Y I        + ++    V A+  S T  ++  G EY+  V   
Sbjct: 6905 TWEPPEYDGGAEITNYVIELRDKTSIRWDTAM-TVRAEDLSATVTDVVEGQEYSFRVRAQ 6963

Query: 1250 --VKDDKES-----VPISDTIIPEVPQLTDLSFVDITDSSIGLRWTPL---NSSTIIGYR 1299
              +   K S     V ++D I    P + +L+  D T SS+ L+W P      S I+GY 
Sbjct: 6964 NRIGVGKPSAATPFVKVADPIERPSPPV-NLTSSDQTQSSVQLKWEPPLKDGGSPILGYI 7022

Query: 1300 ITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLT------ 1353
            I     G+   I  +        Y VTGLE G  Y   V      G S P+ +       
Sbjct: 7023 IERCEEGKDNWIRCNMKLVPELTYKVTGLEKGNKYLYRVSAENKAGVSDPSEILGPLTAD 7082

Query: 1354 ----------------QQTAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVK 1397
                             +  VP P  +   + G      TW     +  T   V+   +K
Sbjct: 7083 DAFVEPTMDLSAFKDGLEVIVPNPITILVPSTGYPRPTATWCFGDKVLETGDRVK---MK 7139

Query: 1398 NEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHE-STPLRGRQKTGLDSPTGID 1456
                 AEL ISPS+ +      L     V ++S   + +  + P          +P  + 
Sbjct: 7140 TLSAYAELVISPSERSDKGIYTLKLENRVKTISGEIDVNVIARP---------SAPKELK 7190

Query: 1457 FSDITANSFTVHWIAP----RATITGYRIRHHPEHFSGRPREDRVPHSRNSI--TLTNLT 1510
            F DIT +S  + W  P     + +TGY +    +    R    +V      +  T+ +L 
Sbjct: 7191 FGDITKDSVHLTWEPPDDDGGSPLTGYVVE---KREVSRKTWTKVMDFVTDLEFTVPDLV 7247

Query: 1511 PGTEYVVSIVALN-------GREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAP- 1562
             G EY+  + A N          + P+ +   +TV D P +++    T  S+ ++WD P 
Sbjct: 7248 QGKEYLFKVCARNKCGPGEPAYVDEPVNMSTPATVPDPPENVKWRDRTANSIFLTWDPPK 7307

Query: 1563 ---AVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSP 1619
                  ++ Y +     G +  V     P +++   ++GL+ G  Y   V A+  +G   
Sbjct: 7308 NDGGSRIKGYIVERCPRGSDKWV-ACGEPVAETKMEVTGLEEGKWYAYRVKALNRQG--- 7363

Query: 1620 ASSKPISINYRTEIDKPS-QMQVTDVQDNS---ISVKWLPSSSPVTGYRV----TTTPKN 1671
             +SKP          +P+ ++Q  D Q+     + VK L   +   G ++    T T K 
Sbjct: 7364 -ASKP---------SRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKP 7413

Query: 1672 GPGPTKTKT--AGPDQTEMTIEGL--QPTVEYVVS---------VYAQNPSGESQPLVQT 1718
             P  T TK          +TIE +  + TV  V S         + A N  G +  +V+ 
Sbjct: 7414 EPKITWTKADMILKQDKRITIENVPKKSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEV 7473

Query: 1719 AVTNIDR---PKGLAFTDVDVDSIKIAWESPQ----GQVSRYRVTYSSPEDGI-HELFPA 1770
             V  +D+   P     TDV  +S  + W  P+     +++ Y V   + +  + H+L  +
Sbjct: 7474 NV--LDKPGPPAAFDITDVTNESCLLTWNPPRDDGGSKITNYVVERRATDSEVWHKL--S 7529

Query: 1771 PDGEEDTAELQGLRPGSEYTVSVVA-----LHDDMESQPLIGTQSTAIPA-PTDLKFTQV 1824
               ++   +   L P  EY   V A     + + +++ P+        P  PT L+ + +
Sbjct: 7530 STVKDTNFKATKLIPNKEYIFRVAAENMYGVGEPVQASPITAKYQFDPPGPPTRLEPSDI 7589

Query: 1825 TPTSLSAQWTPPN----VQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYE 1880
            T  +++  W  P+      +TGY V     +    ++   +    ++  V GL    KY 
Sbjct: 7590 TKDAVTLTWCEPDDDGGSPITGYWVERLDPDTDKWVRCNKMPVKDTTYRVKGLTNKKKYR 7649

Query: 1881 VSVYALKDTLTSRPAQG-----VVTTLENVSPPRRARVTDATETTITISWRTKTE----- 1930
              V A       +P++      +   ++   PP +  V D  +T++ ++W TK E     
Sbjct: 7650 FRVLAENLAGPGKPSKSTEPILIKDPIDPPWPPGKPTVKDVGKTSVRLNW-TKPEHDGGA 7708

Query: 1931 TITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPV---- 1986
             I  + ++ +       ++         + + GL  G +Y   +  +N    S P     
Sbjct: 7709 KIESYVIEMLKTGTDEWVRVAEGVPTTQHLLPGLMEGQEYSFRVRAVNKAGESEPSEPSD 7768

Query: 1987 VIDASTAIDAPSNLRFLAT---TPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREVV 2039
             +     +  PS  R+L     T N+  + W  P     + IT YI++         + V
Sbjct: 7769 PVLCREKLYPPSPPRWLEVINITKNTADLKWTVPEKDGGSPITNYIVEKRDVRRKGWQTV 7828

Query: 2040 PRPRPGVTEATITGLEPGTEYTIYVIA 2066
                   T+ T+T L  G+ Y   V A
Sbjct: 7829 DTTVKD-TKCTVTPLTEGSLYVFRVAA 7854



 Score = 96.3 bits (238), Expect = 3e-19
 Identities = 294/1454 (20%), Positives = 518/1454 (35%), Gaps = 209/1454 (14%)

Query: 684   IQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSA 743
             I+  G Q + +      + S P+T   +     P  PL      VT +TA    ++W   
Sbjct: 18467 IRTDGGQYILKLSNVGGTKSIPITVKVLDRPGPPEGPL-----KVTGVTAEKCYLAWNPP 18521

Query: 744   SDTVSGFRVEYELSEEGDEPQYLDLPSTATSVN-----IPDLLPGRKYI-----VNVYQI 793
                  G  + + + E+  E   L     +T V      +  LLPG +YI     VN Y I
Sbjct: 18522 LQD-GGANISHYIIEKR-ETSRLSWTQVSTEVQALNYKVTKLLPGNEYIFRVMAVNKYGI 18579

Query: 794   SEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRP----QAPITGYRIVYSPSV 849
              E  E   + + +    P  P  P V  +   S+VV W+RP       I GY I+     
Sbjct: 18580 GEPLESGPVTACNPYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGY-ILEKRDK 18638

Query: 850   EGSSTELNLPETANSVTL--SDLQPGVQYNITIYAVEE---NQESTPVVIQQETTGTPRS 904
             EG        +T   + L  + L  G  Y   + A       + S P V  +        
Sbjct: 18639 EGVRWTKCNKKTLTDLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYR------AC 18692

Query: 905   DTVPSPRDLQFVEVTDV---KVTIMWTPP----ESAVTGYRVDV------------IPVN 945
             D +  P      +VTD     V++ W+ P     + V GY V+V             P  
Sbjct: 18693 DALYPPGPPSNPKVTDTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAADEWTTCTPPTG 18752

Query: 946   LPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLT------AQQ-----T 994
             L G+              VT L     Y F++ A++     +P T      AQ+      
Sbjct: 18753 LQGKQ-----------FTVTKLKENTEYNFRICAINSEGVGEPATLPGSVVAQERIEPPE 18801

Query: 995   TKLDAPTNLQFVNETDSTVLVRWT---PPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKY 1051
              +LDA      V    +T+ +  T    P  ++   +    LT R    Q  V  S +  
Sbjct: 18802 IELDADLRKVVVLRASATLRLFVTIKGRPEPEVKWEKAEGILTDRA---QIEVTSSFTML 18858

Query: 1052  PLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAP 1111
              + N+        +L     +        V     P + +     EV + ++ ++W P  
Sbjct: 18859 VIDNVTRFDSGRYNLTLENNSGSKTAFVNVRVLDSPSAPVNLTIREVKKDSVTLSWEPPL 18918

Query: 1112  RIGFKLGVRPSQGGEAPREVTSDSGSIV----------VSGLTPGVEYVYTIQVLRD--- 1158
               G   G + +      RE T  + + +          +  L  G  Y + +    +   
Sbjct: 18919 IDG---GAKITNYIVEKRETTRKAYATITNNCTKTTFRIENLQEGCSYYFRVLASNEYGI 18975

Query: 1159  GQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT---PDITGYRITTTPTNG 1215
             G   +     KV  P  PP  + L  +      T+ WE+  +     ITGY +       
Sbjct: 18976 GLPAETTEPVKVSEPPLPPGRVTL-VDVTRNTATIKWEKPESDGGSKITGYVVEMQTKGS 19034

Query: 1216  QQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPEVPQLTDLSF 1275
             ++ ++  +V   +    T   L+ G EY   V  V +   S P     +P + +  ++  
Sbjct: 19035 EKWSTCTQVKTLE---ATISGLTAGEEYVFRVAAVNEKGRSDP-RQLGVPVIARDIEIK- 19089

Query: 1276  VDITDSSIGLRWTPLNSSTIIGYRITVVAAG----------EGIPIFEDFVDSSVGYYTV 1325
                   S+ L +   N       +I V   G          +G  + E    +     TV
Sbjct: 19090 -----PSVELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTV 19144

Query: 1326  TGL--EPGIDYDISVITLI----NGGESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTWA 1379
             T L  +     D+    L      G  + P T+       PP  +R   +  D++ ++W 
Sbjct: 19145 TSLSIKEASKEDVGTYELCVSNSAGSITVPITIIVLDRPGPPGPIRIDEVSCDSITISWN 19204

Query: 1380  PPP---SIDLTNFLVRYSPVKNEEDVAE---LSISPSDNAVVLTNLLPGTEYVVSVSS-- 1431
             PP       ++N++V     K E        +S + +  ++ +  L  G+EY   V +  
Sbjct: 19205 PPEYDGGCQISNYIVE----KKETTSTTWHIVSQAVARTSIKIVRLTTGSEYQFRVCAEN 19260

Query: 1432  ---VYEQHESTPLRGRQKTGLDSPTGI-DFSDITANSFTVHWIAP----RATITGYRIRH 1483
                     ES+ +          P G       T ++  V W  P     + + GY + +
Sbjct: 19261 RYGKSSYSESSAVVAEYPFSPPGPPGTPKVVHATKSTMLVTWQVPVNDGGSRVIGYHLEY 19320

Query: 1484  HPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN----GREESPLLIGQQSTVS 1539
                      + +++  +   + ++ L  G  Y   + A N    G+              
Sbjct: 19321 KERSSILWSKANKILIADTQMKVSGLDEGLMYEYRVYAENIAGIGKCSKSCEPVPARDPC 19380

Query: 1540  DVPRDLEVVAATPTSLLISWDAP----AVTVRYYRITYGETGGNSPVQEFTVPGSKSTAT 1595
             D P   EV   T  S+ + W  P       +  Y +   E      ++       ++   
Sbjct: 19381 DPPGQPEVTNITRKSVSLKWSKPHYDGGAKITGYIVERRELPDGRWLKCNYTNIQETYFE 19440

Query: 1596  ISGLKPGVDYTITVYAVTGRGD-SPASSKPISINYRTEIDKPSQMQVTDVQDNSI--SVK 1652
             ++ L     Y   V+A       S  S     I  + +++ P  M     +D  +  + +
Sbjct: 19441 VTELTEDQRYEFRVFARNAADSVSEPSESTGPIIVKDDVEPPRVMMDVKFRDVIVVKAGE 19500

Query: 1653  WLPSSSPVTG--YRVTTTPKNG---PGPTKTKTAGPD-QTEMTIEGL--QPTVEYVVSVY 1704
              L  ++ + G    V +  K+G       +T+    D  T +T++    + T +YV+++ 
Sbjct: 19501 VLKINADIAGRPLPVISWAKDGIEIEERARTEIISTDNHTLLTVKDCIRRDTGQYVLTL- 19559

Query: 1705  AQNPSGESQPLVQTAVTNIDRPKG--LAFTDVDVDSIKIAWESPQ----GQVSRYRVTYS 1758
              +N +G     V   V +   P    L    +  +   ++W  PQ      +  Y V   
Sbjct: 19560 -KNVAGTRSVAVNCKVLDKPGPPAGPLEINGLTAEKCSLSWGRPQEDGGADIDYYIV--- 19615

Query: 1759  SPEDGIHELFPAPDGE--EDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPA- 1815
                +  H  +   +GE    + ++  L  G+EY   V  ++     +PL   +S AI A 
Sbjct: 19616 EKRETSHLAWTICEGELQMTSCKVTKLLKGNEYIFRVTGVNKYGVGEPL---ESVAIKAL 19672

Query: 1816  --------PTDLKFTQVTPTSLSAQWTPP----NVQLTGYRVRVTPKEKTGPMKEINLAP 1863
                     PT L+ T VT  S++  W+ P      +++GY +    K     ++      
Sbjct: 19673 DPFTVPSPPTSLEITSVTKESMTLCWSRPESDGGSEISGYIIERREKNSLRWVRVNKKPV 19732

Query: 1864  DSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQ--GVVTTLENV---SPPRRARVTDATE 1918
                 V  +GL    +YE  VYA      S P++   ++   + V   SPP + ++ D+ +
Sbjct: 19733 YDLRVKSTGLREGCEYEYRVYAENAAGLSLPSETSPLIRAEDPVFLPSPPSKPKIVDSGK 19792

Query: 1919  TTITISWRTKT----ETITGFQVD---AVPANGQTPIQRTIKPDVRSYTITGLQPGTDYK 1971
             TTITI+W          ITG+ V+   +   + +T IQ     +   YTI+GL  G +Y 
Sbjct: 19793 TTITIAWVKPLFDGGAPITGYTVEYKKSDDTDWKTSIQSLRGTE---YTISGLTTGAEYV 19849

Query: 1972  IYLYTLNDNARSSP 1985
               + ++N    S P
Sbjct: 19850 FRVKSVNKVGASDP 19863



 Score = 95.5 bits (236), Expect = 6e-19
 Identities = 319/1473 (21%), Positives = 540/1473 (36%), Gaps = 232/1473 (15%)

Query: 777   IPDLLPGRKYIVNVYQISEDG--EQSLILSTSQTTAPDAPPD------PTVDQVDDTSIV 828
             + DL+ G +Y   V  ++  G  + S  +       PD PP         V++  + +IV
Sbjct: 9773  VEDLVEGGEYEFRVKAVNAAGVSKPSATVGPCDCQRPDMPPSIDLKEFMEVEEGTNVNIV 9832

Query: 829   VR----------WSR--PQAPITGYRIVYSPSVE----GSSTELNLPETANSVTLSDLQP 872
              +          W +  P+ P     ++Y   V       +  L +P++  S T      
Sbjct: 9833  AKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDT------ 9886

Query: 873   GVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE- 931
             G+    TI AV  N  +    ++    G P     P    ++F  V+  ++T+ W PP+ 
Sbjct: 9887  GLY---TITAVN-NLGTASKEMRLNVLGRPGPPVGP----IKFESVSADQMTLSWFPPKD 9938

Query: 932   ---SAVTGYRVDVIPVNLPG-EHGQRLPISRNTFAEVTGLSPGVTYYFKVFA-----VSH 982
                S +T Y ++    N     H    P  +     +  L  G  Y F++ A     +  
Sbjct: 9939  DGGSKITNYVIEKREANRKTWVHVSSEP--KECTYTIPKLLEGHEYVFRIMAQNKYGIGE 9996

Query: 983   GRESKPLTAQQTTKLD-APTNLQFVNETDSTVLVRWTPPR----AQITGYRLTVGLTRRG 1037
               +S+P TA+    +  AP      + T +++ V W  P     + +TGY L +  T   
Sbjct: 9997  PLDSEPETARNLFSVPGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPVTGYWLEMKDTTSK 10056

Query: 1038  QPRQYNVGPSVS-----KYPLRNLQPASEYTVSLVAIKGNQESPK------ATGVFTTLQ 1086
             + ++ N  P  +      Y +  L   S+Y   + AI      P       AT       
Sbjct: 10057 RWKRVNRDPIKAMTLGVSYKVTGLIEGSDYQFRVYAINAAGVGPASLPSDPATARDPIAP 10116

Query: 1087  PGSSIPPYNTEVTETTIVITWTPAPRIGFKLG----VRPSQGGEAPREVTSDSG----SI 1138
             PG   P   T+ T+++  + W+P  + G        V   + G+   E   D       +
Sbjct: 10117 PGPPFPKV-TDWTKSSADLEWSPPLKDGGSKVTGYIVEYKEEGKEEWEKGKDKEVRGTKL 10175

Query: 1139  VVSGLTPGVEYVYTIQVLRD---GQERDAPIVNKVVTPLSPPTNLHLEANP-DTGVLTVS 1194
             VV+GL  G  Y + ++ +     G+  +   V ++   L  P +L L+A+  D  V+   
Sbjct: 10176 VVTGLKEGAFYKFRVRAVNIAGIGEPGEVTDVIEMKDRLVSP-DLQLDASVRDRIVVHAG 10234

Query: 1195  WERSTTPDITGYRITTTPTNGQQGNSLEEVV---HADQSSCTFDNLSPGLEYNVSVYTVK 1251
                     ++G    T   N  +    +E      A  SS    N     +    VY++ 
Sbjct: 10235 GVIRIIAYVSGKPPPTVTWNMNERTLPQEATIETTAISSSMVIKNCQRSHQ---GVYSLL 10291

Query: 1252  DDKESVPISDTIIPEV-----PQLTDLSFVDITDSSIGLRW-TPLNS--STIIGYRITVV 1303
                E+     TII +V     P  T     ++T+ S  L W +P +   S I  Y I   
Sbjct: 10292 AKNEAGERKKTIIVDVLDVPGPVGTPFLAHNLTNESCKLTWFSPEDDGGSPITNYVIEKR 10351

Query: 1304  AAGEGI--PIFEDFVDSSVGYYTVTGLEPGIDY--DISVITLINGGESAPTT----LTQQ 1355
              +      P+       +    TV GL  G  Y   I+    I  G    T+    + + 
Sbjct: 10352 ESDRRAWTPVTYTVTRQNA---TVQGLIQGKAYFFRIAAENSIGMGPFVETSEALVIREP 10408

Query: 1356  TAVPP-PTDLRFTNIGPDTMRVTWAPPP---SIDLTNFLVRYSPVKNEEDVAELSISPSD 1411
               VP  P DL    +  +T+ +TW PP      ++ N+++    +  E+     + +   
Sbjct: 10409 ITVPERPEDLEVKEVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEKFHKVTNDNLLS 10468

Query: 1412  NAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQ----KTGLDSPT-GIDFSDITANSFT 1466
                 +  L  G  Y   VS+V    +  P    +    K  L  PT  +DF D      T
Sbjct: 10469 RKYTVKGLKEGDTYEYRVSAVNIVGQGKPSFCTKPITCKDELAPPTLHLDFRD----KLT 10524

Query: 1467  VHWIAPRATITGYRIRHHPEHFSGRPR------EDRVPHSRNSITLTNLTPGTEYVVSIV 1520
             +  +     +TG         +SG+P+      +D      +  T    TP T  +  I 
Sbjct: 10525 IR-VGEAFALTG--------RYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATLALEKIK 10575

Query: 1521  ALNGREESPLLIGQQST--------VSDVPRDLEVVA------ATPTSLLISWDAP---- 1562
             A         ++ + ST        V+ V R    V        T   ++ISW  P    
Sbjct: 10576 AKRSDSGKYCVVVENSTGSRKGFCQVNVVDRPGPPVGPVSFDEVTKDYMVISWKPPLDDG 10635

Query: 1563  AVTVRYYRITYGETGGN--SPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDS-P 1619
                +  Y I   E G +   PV   T   +K+T  +S L  G DY   ++A    G S P
Sbjct: 10636 GSKITNYIIEKKEVGKDVWMPV---TSASAKTTCKVSKLLEGKDYIFRIHAENLYGISDP 10692

Query: 1620  ASSKPISINYRTEI-DKPSQMQVTDVQDNSISVKWLP---SSSPVTGY---RVTTTPKNG 1672
               S  +    R  + D P Q  VT+V  +S  V W        P+T Y   +  T  K  
Sbjct: 10693 LVSDSMKAKDRFRVPDAPDQPIVTEVTKDSALVTWNKPHDGGKPITNYILEKRETMSKRW 10752

Query: 1673  PGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQN------PSGESQPL-VQTAVTNIDR 1725
                TK        T+  +  L    +Y   V A+N      PS  S+P+  +  +     
Sbjct: 10753 ARVTKDPIH--PYTKFRVPDLLEGCQYEFRVSAENEIGIGDPSPPSKPVFAKDPIAKPSP 10810

Query: 1726  PKGLAFTDVDVDSIKIAWESPQ----GQVSRYRVTYSSPEDGI-HELFPAPDGEEDTA-E 1779
             P      D   +S+ + W+ P+     ++  Y V Y    D         P+   +T  +
Sbjct: 10811 PVNPEAIDTTCNSVDLTWQPPRHDGGSKILGYIVEYQKVGDEEWRRANHTPESCPETKYK 10870

Query: 1780  LQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTS-LSAQWTPPNV 1838
             + GLR G  Y   V+A++   ES P        +P P  +K     P   L A       
Sbjct: 10871 VTGLRDGQTYKFRVLAVNAAGESDP------AHVPEPVLVKDRLEPPELILDANMAREQH 10924

Query: 1839  QLTGYRVRVT------PKEKTGPMKEINLAPDSSSVVVSGLMVATKYEV--------SVY 1884
                G  +R++      P  K    KE   AP  + + V+   V +K E+         +Y
Sbjct: 10925 IKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARIDVTP--VGSKLEIRNAAHEDGGIY 10982

Query: 1885  AL--KDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTE----TITGFQVD 1938
             +L  ++   S+     V  L+   PPR   V++  + +  ++W+   +     IT + V+
Sbjct: 10983 SLTVENPAGSKTVSVKVLVLDKPGPPRDLEVSEIRKDSCYLTWKEPLDDGGSVITNYVVE 11042

Query: 1939  A--VPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPV-------VID 1989
                V +   +P+  T K   +S+    L  G  Y   +   N   R   V        +D
Sbjct: 11043 RRDVASAQWSPLSATSKK--KSHFAKHLNEGNQYLFRVAAENQYGRGPFVETPKPIKALD 11100

Query: 1990  ASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREVVPRPRPG 2045
                    P +L  +      + + W  P     + ITGY+++Y++ G+  ++ +      
Sbjct: 11101 PLHPPGPPKDLHHVDVDKTEVSLVWNKPDRDGGSPITGYLVEYQEEGT--QDWIKFKTVT 11158

Query: 2046  VTEATITGLEPGTEYTIYVIALKNNQKSEPLIG 2078
               E  +TGL+ G  Y   V       K+E ++G
Sbjct: 11159 NLECVVTGLQQGKTYRFRV-------KAENIVG 11184



 Score = 95.1 bits (235), Expect = 7e-19
 Identities = 312/1572 (19%), Positives = 569/1572 (36%), Gaps = 228/1572 (14%)

Query: 616   ITETPSQPNSHPIQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLK 672
             +T T     S  + W  P+    S +  Y++  +PK +  +W         N+  + GL 
Sbjct: 17914 VTLTDVSQTSASLMWEKPEHDGGSRVLGYVVEMQPKGTE-KWSIVAESKVCNA-VVTGLS 17971

Query: 673   PGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETT---PFSP--LVATSES 727
              G  Y+ ++ +  + G  +             PV +  +T + +   PF+   + A  + 
Sbjct: 17972 SGQEYQFRVKAYNEKGKSD-------PRVLGVPVIAKDLTIQPSLKLPFNTYSIQAGEDL 18024

Query: 728   VTEITASSFV---VSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGR 784
               EI         +SWV   + +              +   +++  TATS  +  +  G 
Sbjct: 18025 KIEIPVIGRPRPNISWVKDGEPLK-------------QTTRVNVEETATST-VLHIKEGN 18070

Query: 785   KYIVNVYQISED---GEQSLILSTSQTTAPDAPPDPT-VDQVDDTSIVVRWSRPQ----A 836
             K     Y ++     G  +  LS      P  P  P   D+V    +V+ W  P      
Sbjct: 18071 KDDFGKYTVTATNSAGTATENLSVIVLEKPGPPVGPVRFDEVSADFVVISWEPPAYTGGC 18130

Query: 837   PITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQ 896
              I+ Y +    +   +   ++      ++ ++ L+ G +Y   I+A     +S P+  + 
Sbjct: 18131 QISNYIVEKRDTTTTTWHMVSATVARTTIKITKLKTGTEYQFRIFAENRYGKSAPLDSKA 18190

Query: 897   ETTGTPRSDTVPSPRDLQFV-EVTDVKVTIMWTPPES----AVTGYRVDVIPVN-LPGEH 950
                  P  +  P P    FV  ++  ++ + W  P +     + GY ++    N +    
Sbjct: 18191 VIVQYPFKE--PGPPGTPFVTSISKDQMLVQWHEPVNDGGTKIIGYHLEQKEKNSILWVK 18248

Query: 951   GQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQT----TKLDAPTNLQFV 1006
               + PI    F + TGL  G+ Y FKV A +     KP    +        D P   + +
Sbjct: 18249 LNKTPIQDTKF-KTTGLDEGLEYEFKVSAENIVGIGKPSKVSECFVARDPCDPPGRPEAI 18307

Query: 1007  NETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSV-SKYPLRNLQPASE 1061
               T + V ++W  P     ++ITGY +       G+  + +    + +++ +  L     
Sbjct: 18308 VITRNNVTLKWKKPAYDGGSKITGYIVEKKDLPDGRWMKASFTNVLETEFTVSGLVEDQR 18367

Query: 1062  YTVSLVA--IKGNQESPK-ATGVFTTLQ----PGSSIPPYNTEVT-----ETTIV---IT 1106
             Y   ++A    GN   P  ++G  T       P +S+ P   +V      ET ++   I 
Sbjct: 18368 YEFRVIARNAAGNFSEPSDSSGAITARDEIDAPNASLDPKYKDVIVVHAGETFVLEADIR 18427

Query: 1107  WTPAPRIGFKLGVRPSQGGEAPREVTS--DSGSIVVSGL--TPGVEYVYTIQVLRDGQER 1162
               P P + +    +  +   A  E+ S     ++VV     T G +Y+  +++   G  +
Sbjct: 18428 GKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQYI--LKLSNVGGTK 18485

Query: 1163  DAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWE---RSTTPDITGYRITTTPTNGQQGN 1219
               PI  KV+    PP               ++W    +    +I+ Y I    T+     
Sbjct: 18486 SIPITVKVLDRPGPPEGPLKVTGVTAEKCYLAWNPPLQDGGANISHYIIEKRETSRLSWT 18545

Query: 1220  SLEEVVHADQSSCTFDNLSPGLEY-----NVSVYTVKDDKESVPIS---------DTIIP 1265
              +   V A     T   L PG EY      V+ Y + +  ES P++             P
Sbjct: 18546 QVSTEVQALNYKVT--KLLPGNEYIFRVMAVNKYGIGEPLESGPVTACNPYKPPGPPSTP 18603

Query: 1266  EVPQLTDLSFV-----DITDSSI-------------GLRWTPLNSSTIIGYRITVVAAGE 1307
             EV  +T  S V      + D                G+RWT  N  T+   R+ V    E
Sbjct: 18604 EVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDKEGVRWTKCNKKTLTDLRLRVTGLTE 18663

Query: 1308  GIPI-FEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAVPPPTDLRF 1366
             G    F    +++ G    +  EP + Y         G               PP++ + 
Sbjct: 18664 GHSYEFRVAAENAAGVGEPS--EPSVFYRACDALYPPG---------------PPSNPKV 18706

Query: 1367  TNIGPDTMRVTWAPP---PSIDLTNFLVRYSPVKNEE-DVAELSISPSDNAVVLTNLLPG 1422
             T+    ++ + W+ P       +  ++V       +E                +T L   
Sbjct: 18707 TDTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAADEWTTCTPPTGLQGKQFTVTKLKEN 18766

Query: 1423  TEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGY-RI 1481
             TEY   + ++  +    P                  ++ A+   V  +   AT+  +  I
Sbjct: 18767 TEYNFRICAINSEGVGEPATLPGSVVAQERIEPPEIELDADLRKVVVLRASATLRLFVTI 18826

Query: 1482  RHHPEHFSGRPREDRVPHSRNSITLT---------NLTPGTEYVVSIVALNGREESPLLI 1532
             +  PE      + + +   R  I +T         N+T       ++   N        +
Sbjct: 18827 KGRPEPEVKWEKAEGILTDRAQIEVTSSFTMLVIDNVTRFDSGRYNLTLENNSGSKTAFV 18886

Query: 1533  GQQSTVS-DVPRDLEVVAATPTSLLISWDAPAVT----VRYYRITYGETGGNSPVQEFTV 1587
               +   S   P +L +      S+ +SW+ P +     +  Y +   ET   +     T 
Sbjct: 18887 NVRVLDSPSAPVNLTIREVKKDSVTLSWEPPLIDGGAKITNYIVEKRETTRKA-YATITN 18945

Query: 1588  PGSKSTATISGLKPGVDYTITVYAVT--GRGDSPASSKPISINYRTEIDKPSQMQVTDVQ 1645
               +K+T  I  L+ G  Y   V A    G G    +++P+ ++       P ++ + DV 
Sbjct: 18946 NCTKTTFRIENLQEGCSYYFRVLASNEYGIGLPAETTEPVKVSEPPL--PPGRVTLVDVT 19003

Query: 1646  DNSISVKW-LPSS---SPVTGYRVTTTPKNGPGPTKTKTAGPDQT-EMTIEGLQPTVEYV 1700
              N+ ++KW  P S   S +TGY V    K   G  K  T    +T E TI GL    EYV
Sbjct: 19004 RNTATIKWEKPESDGGSKITGYVVEMQTK---GSEKWSTCTQVKTLEATISGLTAGEEYV 19060

Query: 1701  VSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVD-SIKIAWESPQGQVSRYRVTYSS 1759
               V A N  G S P  Q  V  I R       D+++  S+++ + +   + +R ++    
Sbjct: 19061 FRVAAVNEKGRSDPR-QLGVPVIAR-------DIEIKPSVELPFHTFNVK-AREQLKIDV 19111

Query: 1760  PEDGIHELFP--APDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQ-------- 1809
             P  G  +       DG+    E   +   S  TV+ +++ +   S+  +GT         
Sbjct: 19112 PFKGRPQATVNWRKDGQT-LKETTRVNVSSSKTVTSLSIKE--ASKEDVGTYELCVSNSA 19168

Query: 1810  -STAIPA----------PTDLKFTQVTPTSLSAQWTPPNV----QLTGYRVRVTPKEKTG 1854
              S  +P           P  ++  +V+  S++  W PP      Q++ Y V    KE T 
Sbjct: 19169 GSITVPITIIVLDRPGPPGPIRIDEVSCDSITISWNPPEYDGGCQISNYIVE--KKETTS 19226

Query: 1855  PMKEI-NLAPDSSSVVVSGLMVATKYEVSVYAL----KDTLTSRPAQGVVTTLENVSPPR 1909
                 I + A   +S+ +  L   ++Y+  V A     K + +   A           PP 
Sbjct: 19227 TTWHIVSQAVARTSIKIVRLTTGSEYQFRVCAENRYGKSSYSESSAVVAEYPFSPPGPPG 19286

Query: 1910  RARVTDATETTITISWRTKT----ETITGFQVDAVPANG--QTPIQRTIKPDVRSYTITG 1963
               +V  AT++T+ ++W+         + G+ ++    +    +   + +  D +   ++G
Sbjct: 19287 TPKVVHATKSTMLVTWQVPVNDGGSRVIGYHLEYKERSSILWSKANKILIADTQ-MKVSG 19345

Query: 1964  LQPGTDYKIYLYTLN----DNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPR- 2018
             L  G  Y+  +Y  N         S   + A    D P        T  S+ + W  P  
Sbjct: 19346 LDEGLMYEYRVYAENIAGIGKCSKSCEPVPARDPCDPPGQPEVTNITRKSVSLKWSKPHY 19405

Query: 2019  ---ARITGYIIK 2027
                A+ITGYI++
Sbjct: 19406 DGGAKITGYIVE 19417



 Score = 94.7 bits (234), Expect = 1e-18
 Identities = 315/1607 (19%), Positives = 572/1607 (35%), Gaps = 282/1607 (17%)

Query: 628  IQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISI 684
            + W  P+    + I  Y++    K     W           + + GL  G  Y  ++ ++
Sbjct: 7697 LNWTKPEHDGGAKIESYVIEML-KTGTDEWVRVAEGVPTTQHLLPGLMEGQEYSFRVRAV 7755

Query: 685  QQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSAS 744
             + G  E +              S+ V      + P       V  IT ++  + W +  
Sbjct: 7756 NKAGESEPSE------------PSDPVLCREKLYPPSPPRWLEVINITKNTADLKW-TVP 7802

Query: 745  DTVSGFRVEYELSEEGDEP----QYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGE-- 798
            +   G  +   + E+ D      Q +D     T   +  L  G  Y+  V   +  G+  
Sbjct: 7803 EKDGGSPITNYIVEKRDVRRKGWQTVDTTVKDTKCTVTPLTEGSLYVFRVAAENAIGQSD 7862

Query: 799  ----QSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ----APITGYRIVYSPSVE 850
                +  +L+    T P  P    V  V    + ++W  P+     PI  Y I     + 
Sbjct: 7863 YTEIEDSVLAKDTFTTPGPPYALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKERL- 7921

Query: 851  GSSTELNLPETAN---SVTLSDLQPGVQYNITIYAVEEN-----QESTPVVIQQETTGTP 902
              +  +   +TA    +  ++D+  G +    + A  E       E T ++  ++ T  P
Sbjct: 7922 -GTRWVKAGKTAGPDCNFRVTDVIEGTEVQFQVRAENEAGVGHPSEPTEILSIEDPTSPP 7980

Query: 903  RSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPVNLPGEHGQRL---P 955
                   P DL   +     + I W PPE    S + GY V++ PV    E   R+   P
Sbjct: 7981 SP-----PLDLHVTDAGRKHIAIAWKPPEKNGGSPIIGYHVEMCPVGT--EKWMRVNSRP 8033

Query: 956  ISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLV 1015
            I    F    G+ P   Y  +V AV+    S+P    +      P     ++     ++V
Sbjct: 8034 IKDLKFKVEEGVVPDKEYVLRVRAVNAIGVSEPSEISENVVAKDPDCKPTIDLETHDIIV 8093

Query: 1016 RWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPL-RNLQPASEYTVSLVAIKGNQE 1074
                    I G +L++ +  R  P      P+VS +   + ++ +   T+    I  + E
Sbjct: 8094 --------IEGEKLSIPVPFRAVPV-----PTVSWHKDGKEVKASDRLTMKNDHISAHLE 8140

Query: 1075 SPKAT----GVFT-TLQP--GSSIPPYN---------------TEVTETTIVITWTP--- 1109
             PK+     G++T TL+   GS+    N               +++T+++  +TW P   
Sbjct: 8141 VPKSVRADAGIYTITLENKLGSATASINVKVIGLPGPCKDIKASDITKSSCKLTWEPPEF 8200

Query: 1110 ---APRIGFKLGVRPSQGGEAPREVTSDSGSI--VVSGLTPGVEYVYTIQVLRD-GQERD 1163
                P + + L  R + G      V S    +   V  L P  EY + ++ +   G    
Sbjct: 8201 DGGTPILHYVLERREA-GRRTYIPVMSGENKLSWTVKDLIPNGEYFFRVKAVNKVGGGEY 8259

Query: 1164 APIVNKVVT-----PLSPPTNLHLEANPDTGVLTVSWERSTTPD---ITGYRITTTPTNG 1215
              + N V+      P  PP ++ +  NP    +T++W+         I GY I       
Sbjct: 8260 IELKNPVIAQDPKQPPDPPVDVEVH-NPTAEAMTITWKPPLYDGGSKIMGYIIEKIAKGE 8318

Query: 1216 QQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYT-----VKDDKESVPISDTIIP-EVPQ 1269
            ++     E +     + T   L  G EY   V       + +   + P +  + P + P+
Sbjct: 8319 ERWKRCNEHL-VPILTYTAKGLEEGKEYQFRVRAENAAGISEPSRATPPTKAVDPIDAPK 8377

Query: 1270 LTDLSFVDIT-------DSSIG------LRWTPLNSSTIIGYRITVVAA-------GEGI 1309
            +   + +++        D+SI       + W   + + I+   I   AA       GE +
Sbjct: 8378 VILRTSLEVKRGDEIALDASISGSPYPTITWIK-DENVIVPEEIKKRAAPLVRRRKGE-V 8435

Query: 1310 PIFEDFVDSSVGYYTVTGLEPGI-----------DYDISVITLIN--GGESAPTTLTQQT 1356
               E FV       ++   + G            D+ + +I + N  G   AP T++   
Sbjct: 8436 QEEEPFVLPLTQRLSIDNSKKGESQLRVRDSLRPDHGLYMIKVENDHGIAKAPCTVSVLD 8495

Query: 1357 AVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVL 1416
               PP +  F +I   ++   W PP   D  + ++ Y+  K ++        P    +V+
Sbjct: 8496 TPGPPINFVFEDIRKTSVLCKWEPPLD-DGGSEIINYTLEKKDK------TKPDSEWIVV 8548

Query: 1417 TNLLPGTEYVVSVSSVYEQHE------------------STPLRGRQKTG-LDSPTGIDF 1457
            T+ L   +Y  SV+ + E  E                  S PL  +   G  D+P     
Sbjct: 8549 TSTLRHCKY--SVTKLIEGKEYLFRVRAENRFGPGPPCVSKPLVAKDPFGPPDAPDKPIV 8606

Query: 1458 SDITANSFTVHWIAPR---ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTE 1514
             D+T+NS  V W  P+   + I GY +     + +   R ++   +     +  L  G  
Sbjct: 8607 EDVTSNSMLVKWNEPKDNGSPILGYWLEKREVNSTHWSRVNKSLLNALKANVDGLLEGLT 8666

Query: 1515 YVVSIVALN----GREESPLLIGQQSTVSD--------VPRDLEVVAATPTSLLISWDAP 1562
            YV  + A N    G+   P       T  D        +PR   V   + T++ + W+ P
Sbjct: 8667 YVFRVCAENAAGPGKFSPP---SDPKTAHDPISPPGPPIPR---VTDTSSTTIELEWEPP 8720

Query: 1563 AVT----VRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDS 1618
            A      +  Y +     G N   +           T+  ++ G DY + V AV   G+ 
Sbjct: 8721 AFNGGGEIVGYFVDKQLVGTNEWSRCTEKMIKVRQYTVKEIREGADYKLRVSAVNAAGEG 8780

Query: 1619 -PASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTK 1677
             P  ++P+++    E  +P  +++       +SVK           R+       P PTK
Sbjct: 8781 PPGETQPVTV---AEPQEPPAVEL------DVSVKGGIQIMAGKTLRIPAVVTGRPVPTK 8831

Query: 1678 --TKTAGP-DQTEMTIEGLQPTVEYVVS-----------VYAQNPSGESQPLVQTAVTNI 1723
              TK  G  D+  + I+ +    E ++            + A N  G      +  V ++
Sbjct: 8832 VWTKEEGELDKDRVVIDNVGTKSELIIKDALRKDHGRYVITATNSCGSKFAAARVEVFDV 8891

Query: 1724 DRP-KGLAFTDVDVDSIKIAWESPQ----GQVSRYRVTYSSPEDGIHELFPAPDGEEDTA 1778
              P   L     +     + W  P+     +++ + +     +  +H      + E    
Sbjct: 8892 PGPVLDLKPVVTNRKMCLLNWSDPEDDGGSEITGFIIERKDAK--MHTWRQPIETERSKC 8949

Query: 1779 ELQGLRPGSEYTVSVVALH-----DDMESQPLIGTQSTAIP-APTDLKFTQVTPTSLSAQ 1832
            ++ GL  G EY   V+A +       +E  P++       P +P  L +T+ T ++++  
Sbjct: 8950 DITGLLEGQEYKFRVIAKNKFGCGPPVEIGPILAVDPLGPPTSPERLTYTERTKSTITLD 9009

Query: 1833 WTPPNVQ----LTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKD 1888
            W  P       + GY +     +K    +       ++S +V  L     YE  V A+ +
Sbjct: 9010 WKEPRSNGGSPIQGYIIEKRRHDKPDFERVNKRLCPTTSFLVENLDEHQMYEFRVKAVNE 9069

Query: 1889 TLTSRPA--QGVVTTLENVSPPRRARVTDATETTIT-------------------ISWRT 1927
               S P+    VV   + V P  + R++   +T                      I W +
Sbjct: 9070 IGESEPSLPLNVVIQDDEVPPTIKLRLSVRGDTIKVKAGEPVHIPADVTGLPMPKIEW-S 9128

Query: 1928 KTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVV 1987
            K ET+     DA+    +   +   K ++          GT      YT+  + R   V 
Sbjct: 9129 KNETVIEKPTDALQITKEEVSRSEAKTELSIPKAVREDKGT------YTVTASNRLGSVF 9182

Query: 1988 IDASTAI-DAPSNLRFLATT---PNSLLVSWQPP----RARITGYII 2026
             +    + D PS  R LA T     S  ++W  P     + IT Y+I
Sbjct: 9183 RNVHVEVYDRPSPPRNLAVTDIKAESCYLTWDAPLDNGGSEITHYVI 9229



 Score = 93.2 bits (230), Expect = 3e-18
 Identities = 379/1860 (20%), Positives = 656/1860 (35%), Gaps = 386/1860 (20%)

Query: 624   NSHPIQWNAPQPSHISKYILRW---RPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQ 680
             N+  I+W  P     SK I  W   + +N++   KE  +P    +Y + GL  G+ Y+ +
Sbjct: 22550 NAMSIRWEEPYHDGGSKIIGYWVEKKERNTILWVKENKVPCLECNYKVTGLVEGLEYQFR 22609

Query: 681   LISIQQYGHQEVTRFDFTTTSTSTPVTS-NTVTGETTPFSPLVATSESVTEITASSFVVS 739
               ++   G  + +         S P+ + N V     P          VT++T S+  + 
Sbjct: 22610 TYALNAAGVSKASE-------ASRPIMAQNPVDAPGRP---------EVTDVTRSTVSLI 22653

Query: 740   WVSAS----DTVSGFRVEYELSEEGDEPQYLDLPSTATSVN---IPDLLPGRKYIVNVYQ 792
             W + +      V G+ +E +   E  + ++L    T  S N   +  L  G  Y   V  
Sbjct: 22654 WSAPAYDGGSKVVGYIIERKPVSEVGDGRWLKCNYTIVSDNFFTVTALSEGDTYEFRVLA 22713

Query: 793   ISEDGEQSLILSTSQTTAPD------APPDPTVD-QVDDTSIVVRWSRPQAPITGYRIVY 845
              +  G   +I   S++T P       APP   +D ++    + +R         G  +V 
Sbjct: 22714 KNAAG---VISKGSESTGPVTCRDEYAPPKAELDARLHGDLVTIR--------AGSDLVL 22762

Query: 846   SPSVEGS----------STELNLPETANS----------VTLSDLQPGVQYNITIYAVEE 885
               +V G             EL+L E  +           +   D     +Y +T+     
Sbjct: 22763 DAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSGKYTLTVKNASG 22822

Query: 886   NQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDV 941
              +  + +V   ++ G     TV          VT  K T+ W+ P+    + +T Y V+ 
Sbjct: 22823 TKAVSVMVKVLDSPGPCGKLTVS--------RVTQEKCTLAWSLPQEDGGAEITHYIVE- 22873

Query: 942   IPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYY-----------FKVFAVS-HGR----E 985
                        R   SR  +  V G  P ++Y            F+V AV+ +G     E
Sbjct: 22874 -----------RRETSRLNWVIVEGECPTLSYVVTRLIKNNEYIFRVRAVNKYGPGVPVE 22922

Query: 986   SKPLTAQQTTKLDAPTNL-QFVNETDSTVLVRWTPPRA----QITGYRLTVGLTRRGQPR 1040
             S+P+ A+ +  + +P  + + V      ++++WT P +    +I+ Y   V    +   R
Sbjct: 22923 SEPIVARNSFTIPSPPGIPEEVGTGKEHIIIQWTKPESDGGNEISNY--LVDKREKKSLR 22980

Query: 1041  QYNVGPSVSKYPLR----NLQPASEYTVSLVAIK--GNQESPKATGVFTTLQPGSSIPPY 1094
                V      Y  R    +L    +Y   + A+   GN E  +A+   +  +P       
Sbjct: 22981 WTRVNKDYVVYDTRLKVTSLMEGCDYQFRVTAVNAAGNSEPSEASNFISCREP------- 23033

Query: 1095  NTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTP----GVEYV 1150
                        ++TP P         PS    APR V +   SI ++   P    G + V
Sbjct: 23034 -----------SYTPGP---------PS----APRVVDTTKHSISLAWTKPMYDGGTDIV 23069

Query: 1151  -YTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRIT 1209
              Y +++    QE+D     +V          H  A       T+     T PD+      
Sbjct: 23070 GYVLEM----QEKDTDQWYRV----------HTNA-------TIRNTEFTVPDLK----- 23103

Query: 1210  TTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPEVPQ 1269
                  GQ+ +     V+    S          EY+ S+  ++      P+    IP++  
Sbjct: 23104 ----MGQKYSFRVAAVNVKGMS----------EYSESIAEIE------PVERIEIPDLEL 23143

Query: 1270  LTDLSFVDITDSSIGLRWTPLNSSTIIGYRITVVA-AGEGIPIFEDFVDSSVGYYTVTGL 1328
               DL       +   LR       ++ G    V+  + +GI +    +  +   Y++  +
Sbjct: 23144 ADDLKKTVTIRAGASLRLMV----SVSGRPPPVITWSKQGIDLASRAIIDTTESYSLLIV 23199

Query: 1329  EPGIDYDISVITLI---NGGESAPTTLTQQTAVPPPT-DLRFTNIGPDTMRVTWAPPPSI 1384
             +    YD    T+      G+ + T L +    P P   ++   +  D++ +TW  P +I
Sbjct: 23200 DKVNRYDAGKYTIEAENQSGKKSATVLVKVYDTPGPCPSVKVKEVSRDSVTITWEIP-TI 23258

Query: 1385  DLTNFLVRYSPVKNEEDVAE---LSISPSDNAVVLTNLLPGTEYVVSV--SSVY---EQH 1436
             D    +  Y   K E  +     ++   S     ++ L+ GT Y   V   ++Y   E  
Sbjct: 23259 DGGAPVNNYIVEKREAAMRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYGIGEPC 23318

Query: 1437  ESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRP 1492
             E++      +  L  P  ++  D+T ++ T+ W  P     + +TGY +       +G  
Sbjct: 23319 ETSDAVLVSEVPL-VPAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACK---AGTE 23374

Query: 1493  REDRVPHSRNSI---TLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVP-RDLEVV 1548
             R  +V   + ++   T+T+L  G +Y+  I A N +  S      + TV+ V  +DL V+
Sbjct: 23375 RWMKVVTLKPTVLEHTVTSLNEGEQYLFRIRAQNEKGVSE----PRETVTAVTVQDLRVL 23430

Query: 1549  AATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKS---------------- 1592
                  S +          R   +     G   P   +   GSK                 
Sbjct: 23431 PTIDLSTMPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAK 23490

Query: 1593  -TATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQ----MQVTDVQDN 1647
              T   + ++   +YT+ +  VTG      +S+ I +     +DKP      +++ ++   
Sbjct: 23491 LTIRETTIRDTGEYTLELKNVTG-----TTSETIKVII---LDKPGPPTGPIKIDEIDAT 23542

Query: 1648  SISVKWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSV 1703
             SI++ W P      +P++GY V     + PG      +    T      L    EYV  V
Sbjct: 23543 SITISWEPPELDGGAPLSGYVVEQRDAHRPGWLPVSESVTRST-FKFTRLTEGNEYVFRV 23601

Query: 1704  YAQNPSGESQPL------VQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQ----GQVSRY 1753
              A N  G    L       ++++     P+ L   DV  D + + W  P+     QV+ Y
Sbjct: 23602 AATNRFGIGSYLQSEVIECRSSIRIPGPPETLQIFDVSRDGMTLTWYPPEDDGGSQVTGY 23661

Query: 1754  RVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALH------DDMESQPLIG 1807
              V                          GL  G EY   V A++          S+P++ 
Sbjct: 23662 IVERKEVRADRWVRVNKVPVTMTRYRSTGLTEGLEYEHRVTAINARGSGKPSRPSKPIVA 23721

Query: 1808  TQSTAIPA-PTDLKFTQVTPTSLSAQWTPPNVQ----LTGYRVRVTPKEKTGPMKEINLA 1862
                 A P  P + + T  T TS+S  W+ P  +    +TGY + +   ++    K     
Sbjct: 23722 MDPIAPPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTKCNTTP 23781

Query: 1863  PDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQ--GVVTTLENVSPP---------RRA 1911
                    ++ L    +Y   V A        PA+  G V   E +  P            
Sbjct: 23782 TKIREYTLTHLPQGAEYRFRVLACNAGGPGEPAEVPGTVKVTEMLEYPDYELDERYQEGI 23841

Query: 1912  RVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGT--D 1969
              V       +TI  + K      F +      GQ   +R +     ++T   ++     D
Sbjct: 23842 FVRQGGVIRLTIPIKGKP-----FPICKWTKEGQDISKRAMIATSETHTELVIKEADRGD 23896

Query: 1970  YKIYLYTLNDNARSSPVVIDASTAIDAPSN----LRFLATTPNSLLVSWQPPR----ARI 2021
                Y   L +      V I     I +P++    L +      S+ VSW+PP     A I
Sbjct: 23897 SGTYDLVLENKCGKKAVYIKVRV-IGSPNSPEGPLEYDDIQVRSVRVSWRPPADDGGADI 23955

Query: 2022  TGYII-KYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRK 2080
              GYI+ + E P +    +  R R   T   + GL+   EY   V A      S+PL   +
Sbjct: 23956 LGYILERREVPKAAWYTIDSRVRG--TSLVVKGLKENVEYHFRVSAENQFGISKPLKSEE 24013

Query: 2081  KTVQKTPFVTHPGYDTGNGIQLPGTSGQQPSVGQQMIFEEHGFRRTTPPTTATPIRHRPR 2140
                 KTP                                        PP         P 
Sbjct: 24014 PVTPKTPL--------------------------------------NPP--------EPP 24027

Query: 2141  PYPPNVGQEALSQTTISWAPFQD-----TSEYIISCHPVGTDEEPLQFRVPGTSTSATLT 2195
               PP V     S  ++SW+  +D      + Y I      TD+     +   T+T  T+T
Sbjct: 24028 SNPPEVLDVTKSSVSLSWSRPKDDGGSRVTGYYIERKETSTDKWVRHNKTQITTTMYTVT 24087

Query: 2196  GLTRGATYNIIVEALKD---QQRHKVREEVVTVGNSVNEGLNQPTDDSCFDPYTVSHYAV 2252
             GL   A Y   + A  D    +     E VV       +  ++P+     +  ++S  +V
Sbjct: 24088 GLVPDAEYQFRIIAQNDVGLSETSPASEPVV-----CKDPFDKPSQPGELEILSISKDSV 24142

Query: 2253  GDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHDNGVNYKIGEKWDRQGENGQMMSCT 2312
               +WE+    G K   + LG+   + +   S W   N    K     D+Q   G ++  T
Sbjct: 24143 TLQWEKPECDGGK---EILGYWVEYRQSGDSAWKKSNKERIK-----DKQFTIGGLLEAT 24194



 Score = 90.5 bits (223), Expect = 2e-17
 Identities = 317/1530 (20%), Positives = 556/1530 (36%), Gaps = 208/1530 (13%)

Query: 728   VTEITASSFVVSW----VSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPG 783
             +T+I+ +S  +SW          ++G+ VE     +G   +      T T   I  L   
Sbjct: 20471 ITDISKNSVSLSWQQPAFDGGSKITGYIVERRDLPDGRWTKASFTNVTETQFIISGLTQN 20530

Query: 784   RKYIVNVYQISEDGEQSLILSTSQTTAP----DAPPDPTVDQVDDTSIVVRWS-----RP 834
              +Y   V+  +  G    I + S+   P    D+   P +D   + + VV++      + 
Sbjct: 20531 SQYEFRVFARNAVGS---ISNPSEVVGPITCIDSYGGPVIDLPLEYTEVVKYRAGTSVKL 20587

Query: 835   QAPITGYRIVYSPSVEGSSTELNLPETA-----NSVTLSDL--QPGVQYNITIYAVEENQ 887
             +A I+G     +P++E    +  L   A     N+  L+ +  +   + N   Y ++   
Sbjct: 20588 RAGISGKP---APTIEWYKDDKELQTNALVCVENTTDLASILIKDADRLNSGCYELKLRN 20644

Query: 888   E--STPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDV 941
                S    I+ +    P     P    ++F  VT  K+T++W PP     + +T Y V+ 
Sbjct: 20645 AMGSASATIRVQILDKPG----PPGGPIEFKTVTAEKITLLWRPPADDGGAKITHYIVEK 20700

Query: 942   -----IPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTK 996
                  +  ++  EH +   I+       T +  G  Y F+V AV+     +PL +     
Sbjct: 20701 RETSRVVWSMVSEHLEECIIT------TTKIIKGNEYIFRVRAVNKYGIGEPLESDSVVA 20754

Query: 997   LDA-----PTNLQFVNE-TDSTVLVRWTPPRAQ----ITGYRLTVGLTRR-GQPRQYNVG 1045
              +A     P  +  V + T +++ V W+ P A     I+GY L     +  G  +     
Sbjct: 20755 KNAFVTPGPPGIPEVTKITKNSMTVVWSRPIADGGSDISGYFLEKRDKKSLGWFKVLKET 20814

Query: 1046  PSVSKYPLRNLQPASEYTVSLVAIKGNQESP--KATGVFTTLQP-GSSIPPYNTEVTETT 1102
                ++  +  L   S+Y   + A+    + P  + +  +    P     PP    + ++T
Sbjct: 20815 IRDTRQKVTGLTENSDYQYRVCAVNAAGQGPFSEPSEFYKAADPIDPPGPPAKIRIADST 20874

Query: 1103  ---IVITWTP------APRIGFKLGVRPSQGGEAPREVTSDSGSI-----VVSGLTPGVE 1148
                I + W+       +   G+ + +R  QG E      S  G +     VVS L PGV 
Sbjct: 20875 KSSITLGWSKPVYDGGSAVTGYVVEIR--QGEEEEWTTVSTKGEVRTTEYVVSNLKPGVN 20932

Query: 1149  YVYTIQVLRDGQERDAPIVNKVVTP---LSPP---------TNLHLEANPDTGVL----- 1191
             Y + +  +    + +   +N+ V     L  P         T++  +A  D  VL     
Sbjct: 20933 YYFRVSAVNCAGQGEPIEMNEPVQAKDILEAPEIDLDVALRTSVIAKAGEDVQVLIPFKG 20992

Query: 1192  ----TVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSV 1247
                 TV+W +      +  R +   T+     ++ +V   D             +Y +++
Sbjct: 20993 RPPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTG-----------KYILTI 21041

Query: 1248  YTVKDDKESVPISDTIIPEVPQLTDLSFVDITDSSIGLRWTPL---NSSTIIGYRITVVA 1304
                  + +S  +S  ++        L    ++  ++ L W P      S II Y I    
Sbjct: 21042 ENGVGEPKSSTVSVKVLDTPAACQKLQVKHVSRGTVTLLWDPPLIDGGSPIINYVIEKRD 21101

Query: 1305  AGEGIPIFEDFVDSSVGYYTVTGLEPG-IDYDISVITLINGGESAPTTLTQQTA-VPPPT 1362
             A +          SS  +  +   E     + +     I  GE   TT   + A VP P 
Sbjct: 21102 ATKRTWSVVSHKCSSTSFKLIDLSEKTPFFFRVLAENEIGIGEPCETTEPVKAAEVPAPI 21161

Query: 1363  -DLRFTNIGPDTMRVTWAPPP---SIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTN 1418
              DL   +    ++ ++W  P       +T ++V     K E+  +   IS +   + ++ 
Sbjct: 21162 RDLSMKDSTKTSVILSWTKPDFDGGSVITEYVVERKG-KGEQTWSHAGISKTCE-IEVSQ 21219

Query: 1419  LLPGTEYVVSVSSVYEQHESTPLRGRQKT--GLDSPTGIDFSDITANSFTVHWIAPRATI 1476
             L   +     V +  E+  S P+     T   L     +D SDI     TV         
Sbjct: 21220 LKEQSVLEFRVFAKNEKGLSDPVTIGPITVKELIITPEVDLSDIPGAQVTVR-------- 21271

Query: 1477  TGYRIRHHPEHFSGRPRED----------------RVPHSRNSITLT----NLTPGTEYV 1516
              G+ + H    + G+P+                  R   + N ITL+        G +Y 
Sbjct: 21272 IGHNV-HLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGGKYT 21330

Query: 1517  VSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVT----VRYYRIT 1572
             V +     R   P+ +      S     +        S+++SWD P       +  Y I 
Sbjct: 21331 VILDNAVCRIAVPITVITLGPPSKPKGPIRFDEIKADSVILSWDVPEDNGGGEITCYSIE 21390

Query: 1573  YGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDS-PASSKPISINYRT 1631
               ET   +  +      +++T  +  L    +Y   V A    G S P  S  I   ++ 
Sbjct: 21391 KRETSQTN-WKMVCSSVARTTFKVPNLVKDAEYQFRVRAENRYGVSQPLVSSIIVAKHQF 21449

Query: 1632  EID-KPSQMQVTDVQDNSISVKW----LPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQT 1686
              I   P +  + +V  + +S+ W        S VTG+ V    +N     K  T+     
Sbjct: 21450 RIPGPPGKPVIYNVTSDGMSLTWDAPVYDGGSEVTGFHVEKKERNSILWQKVNTSPISGR 21509

Query: 1687  EMTIEGLQPTVEYVVSVYAQNPSGESQPLVQT----AVTNIDRPKGLAFTDVDVDSIKIA 1742
             E    GL   ++Y   VYA+N +G S P   +    AV+ +D P    + DV  ++I + 
Sbjct: 21510 EYRATGLVEGLDYQFRVYAENSAGLSSPSDPSKFTLAVSPVDPPGTPDYIDVTRETITLK 21569

Query: 1743  WESPQGQVSRYRVTYSSPEDGIHELFPA---PDGEEDTAELQGLRPGSEYTVSVVALHDD 1799
             W  P        V YS  +   +E +      D  E    + GL PG  Y   ++A +  
Sbjct: 21570 WNPPLRDGGSKIVGYSIEKRQGNERWVRCNFTDVSECQYTVTGLSPGDRYEFRIIARNAV 21629

Query: 1800  MESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEI 1859
                 P   +QS+ I    D     +       ++    +  +G  +R+    +  P+  +
Sbjct: 21630 GTISP--PSQSSGIIMTRDENVPPIV--EFGPEYFDGLIIKSGESLRIKALVQGRPVPRV 21685

Query: 1860  NLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTT-LENVSPPRRARV-TDAT 1917
                 D   +     M  T    S        T R  +GV T   +N S   +A +     
Sbjct: 21686 TWFKDGVEIEKRMNMEITDVLGSTSLFVRDAT-RDHRGVYTVEAKNASGSAKAEIKVKVQ 21744

Query: 1918  ETTITISWRTKTETITGFQV----DAVPANGQTPIQRTI----------------KPDVR 1957
             +T   +    +   ITG ++    DA   +G  PI   I                K + +
Sbjct: 21745 DTPGKVVGPIRFTNITGEKMTLWWDAPLNDGCAPITHYIIEKRETSRLAWALIEDKCEAQ 21804

Query: 1958  SYTITGLQPGTDYKIYLYTLNDNA-----RSSPVVIDAS-TAIDAPSNLRFLATTPNSLL 2011
             SYT   L  G +Y+  +  +N         S PVV     T  DAP        T NS+ 
Sbjct: 21805 SYTAIKLINGNEYQFRVSAVNKFGVGRPLDSDPVVAQIQYTVPDAPGIPEPSNITGNSIT 21864

Query: 2012  VSWQPPRA----RITGYII-KYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIA 2066
             ++W  P +     I  YI+ + EK  +   +V+ +     T   +TGL  G EY  +V+A
Sbjct: 21865 LTWARPESDGGSEIQQYILERREKKSTRWVKVISKRPISETRFKVTGLTEGNEYEFHVMA 21924

Query: 2067  LKNNQKSEPLIGRKKTVQKTPFVTHPGYDT 2096
              +N     P  G  + ++    V  PG  T
Sbjct: 21925 -ENAAGVGPASGISRLIKCREPVNPPGPPT 21953



 Score = 90.1 bits (222), Expect = 2e-17
 Identities = 348/1626 (21%), Positives = 567/1626 (34%), Gaps = 224/1626 (13%)

Query: 624   NSHPIQWNAPQ---PSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKG--LKPGVVYE 678
             +S  + W  P+    S I+ YI+  R   S   W+   +   +   TIK   LK G  Y+
Sbjct: 15951 DSITLSWGPPKYDGGSSINNYIVEKRD-TSTTTWQ--IVSATVARTTIKACRLKTGCEYQ 16007

Query: 679   GQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVV 738
              ++ +  +YG       + T       V          P +P+V  S      +  S  V
Sbjct: 16008 FRIAAENRYGKSTYLNSEPTVAQYPFKVPG-------PPGTPVVTLS------SRDSMEV 16054

Query: 739   SWVSASDTVSGFRVEYELS-EEGDEPQYLDL---PSTATSVNIPDLLPGRKYI--VNVYQ 792
              W           + Y L  +E +   ++ L   P   T      L  G +Y   V+   
Sbjct: 16055 QWNEPISDGGSRVIGYHLERKERNSILWVKLNKTPIPQTKFKTTGLEEGVEYEFRVSAEN 16114

Query: 793   ISEDGEQSLILSTSQTTAPDAPPD-PTVDQVDDTSIVVRWSRPQ----APITGYRIVYSP 847
             I   G+ S +        P  PP  P    V   S+ ++W +P     + ITGY +    
Sbjct: 16115 IVGIGKPSKVSECYVARDPCDPPGRPEAIIVTRNSVTLQWKKPTYDGGSKITGYIVEKKE 16174

Query: 848   SVEG---SSTELNLPETANSVTLSDLQPGVQYNITIYA------VEENQESTPVVIQQET 898
               EG    ++  N+ +T   VT   L    +Y   + A        E  EST  +  ++ 
Sbjct: 16175 LPEGRWMKASFTNIIDTHFEVT--GLVEDHRYEFRVIARNAAGVFSEPSESTGAITARDE 16232

Query: 899   TGTPRSDTVPSPRDLQFVEVTD---VKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLP 955
                PR    P  +D   V   +   V   I   P  +      +  I  +    +  RL 
Sbjct: 16233 VDPPRISMDPKYKDTIVVHAGESFKVDADIYGKPIPT------IQWIKGDQELSNTARLE 16286

Query: 956   ISRNTFAEVTGLSPGV-----TYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNE-T 1009
             I    FA    +   V      Y  K   V+ G  S  +  +   +   P     ++  T
Sbjct: 16287 IKSTDFATSLSVKDAVRVDSGNYILKAKNVA-GERSVTVNVKVLDRPGPPEGPVVISGVT 16345

Query: 1010  DSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVS 1065
                  + W PP     + I  Y +    T R      +         +  L   +EYT  
Sbjct: 16346 AEKCTLAWKPPLQDGGSDIINYIVERRETSRLVWTVVDANVQTLSCKVTKLLEGNEYTFR 16405

Query: 1066  LVAIKGNQ-----ESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWT-PAPR-----IG 1114
             ++A+         ES         + P +   P  T VT+ ++++ W  PA       +G
Sbjct: 16406 IMAVNKYGVGEPLESEPVVAKNPFVVPDAPKAPEVTTVTKDSMIVVWERPASDGGSEILG 16465

Query: 1115  FKLGVRPSQGGEAPREVTSDSGSIV--VSGLTPGVEYVYTIQVLRD-GQERDAP--IVNK 1169
             + L  R  +G    R      G +   V+GL    +Y + +      G    +P     K
Sbjct: 16466 YVLEKRDKEGIRWTRCHKRLIGELRLRVTGLIENHDYEFRVSAENAAGLSEPSPPSAYQK 16525

Query: 1170  VVTPL---SPPTNLHLEANPDTGVLTVSWERSTTP---DITGYRITTTPTNGQQGNSLEE 1223
                P+    PP N  +     + V  +SW +       +I GY +     +  +      
Sbjct: 16526 ACDPIYKPGPPNNPKVIDITRSSVF-LSWSKPIYDGGCEIQGYIVEKCDVSVGEWTMCTP 16584

Query: 1224  VVHADQSSCTFDNLSPGLEYNVSVYTVKD----DKESVPISDTIIPEVPQLTDLSFVDIT 1279
                 ++++   + L    EYN  +  +      +   VP    I+ E  +  D+      
Sbjct: 16585 PTGINKTNIEVEKLLEKHEYNFRICAINKAGVGEHADVP-GPIIVEEKLEAPDI------ 16637

Query: 1280  DSSIGLRWTPLNSSTIIGYRITVVAAGEGIP----------IFEDFVDSSVGYYTVTGLE 1329
             D  + LR   +N       R+ V   G   P          I +  +      +T   L+
Sbjct: 16638 DLDLELRKI-INIRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTSSFTSLVLD 16696

Query: 1330  PGIDYDISVITLI----NGGESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAPPPSID 1385
                 YD    TL     +G +SA  T+       PP +L+ T I  D++ +TW  PP +D
Sbjct: 16697 NVNRYDSGKYTLTLENSSGTKSAFVTVRVLDTPSPPVNLKVTEITKDSVSITW-EPPLLD 16755

Query: 1386  LTNFLVRYSPVKNE---EDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLR 1442
               + +  Y   K E   +  A +  +   N+  +  L  G  Y   V++  E     P +
Sbjct: 16756 GGSKIKNYIVEKREATRKSYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAENEYGIGLPAQ 16815

Query: 1443  GRQKTGL----DSPTGIDFSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPRE 1494
                   +      P  I   D+T NS ++ W  P     + I  Y +    +H       
Sbjct: 16816 TADPIKVAEVPQPPGKITVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKHSEKWSEC 16875

Query: 1495  DRVPHSRNSITLTNLTPGTEYVVSIVALNGREES-PLLIGQQSTVSDVPRDLEVVAA-TP 1552
              RV   +    +TNLT G EY+  +VA+N +  S P  +       D+  + +V  A + 
Sbjct: 16876 ARVKSLQ--AVITNLTQGEEYLFRVVAVNEKGRSDPRSLAVPIVAKDLVIEPDVKPAFSS 16933

Query: 1553  TSLLISWD----APAVTVRYYRITYGETGGNSPVQEFT---VPGSKSTATIS----GLKP 1601
              S+ +  D     P        IT+ + G   P+++ T   V  S    T+S        
Sbjct: 16934 YSVQVGQDLKIEVPISGRPKPTITWTKDG--LPLKQTTRINVTDSLDLTTLSIKETHKDD 16991

Query: 1602  GVDYTITVYAVTGRGDSPASSKPISINYRTEIDKP----SQMQVTDVQDNSISVKWLP-- 1655
             G  Y ITV  V G+       K  SI   T +DKP      ++  DV   SI++ W P  
Sbjct: 16992 GGQYGITVANVVGQ-------KTASIEIVT-LDKPDPPKGPVKFDDVSAESITLSWNPPL 17043

Query: 1656  --SSSPVTGYRV-----TTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNP 1708
                   +T Y V     TTT  +    T  +T       + +  L+   EY   ++A+N 
Sbjct: 17044 YTGGCQITNYIVQKRDTTTTVWDVVSATVARTT------LKVTKLKTGTEYQFRIFAENR 17097

Query: 1709  SG-----ESQPLVQTAVTNIDRPKGLAF-TDVDVDSIKIAWESPQGQVSRYRVTYSSPED 1762
              G     ES P+V         P G  F T +  DS+ I W  P        + Y     
Sbjct: 17098 YGQSFALESDPIVAQYPYKEPGPPGTPFATAISKDSMVIQWHEPVNNGGSPVIGYHLERK 17157

Query: 1763  GIHELFPAPDGE---EDTA-ELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTD 1818
               + +      +    DT  + Q L  G EY   V A +     +    ++      P D
Sbjct: 17158 ERNSILWTKVNKTIIHDTQFKAQNLEEGIEYEFRVYAENIVGVGKASKNSECYVARDPCD 17217

Query: 1819  LKFT----QVTPTSLSAQWTPP----NVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVV 1870
                T     V    ++ QWT P       +TGY V          MK        +   V
Sbjct: 17218 PPGTPEPIMVKRNEITLQWTKPVYDGGSMITGYIVEKRDLPDGRWMKASFTNVIETQFTV 17277

Query: 1871  SGLMVATKYEVSVYALKDT-LTSRPAQ--GVVTTLENVSPPRRARVTDATETTITISWRT 1927
             SGL    +YE  V A       S+P+   G +T  + V  PR +      +T +  +  T
Sbjct: 17278 SGLTEDQRYEFRVIAKNAAGAISKPSDSTGPITAKDEVELPRISMDPKFRDTIVVNAGET 17337

Query: 1928  KTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQ-PGTDYKIYL------------ 1974
                    F+++A       P    ++ D         +   TD+K  L            
Sbjct: 17338 -------FRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRIDGGQ 17390

Query: 1975  YTLNDN----ARSSPV---VIDASTAIDAPSNLRFLATTPNSLLVSWQPP----RARITG 2023
             Y L  +    ++S PV   V+D     + P  ++    T     ++W PP     + I+ 
Sbjct: 17391 YILRASNVAGSKSFPVNVKVLDRPGPPEGP--VQVTGVTSEKCSLTWSPPLQDGGSDISH 17448

Query: 2024  YIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTV 2083
             Y+++ ++  S     V           +T L  G EY   ++A+      EPL      +
Sbjct: 17449 YVVE-KRETSRLAWTVVASEVVTNSLKVTKLLEGNEYVFRIMAVNKYGVGEPL-ESAPVL 17506

Query: 2084  QKTPFV 2089
              K PFV
Sbjct: 17507 MKNPFV 17512



 Score = 88.2 bits (217), Expect = 9e-17
 Identities = 167/815 (20%), Positives = 297/815 (36%), Gaps = 113/815 (13%)

Query: 1342  INGGESAPTTL-TQQTAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEE 1400
             + G +S P T+       PP   L+ T +  +   + W PP      N        +   
Sbjct: 18481 VGGTKSIPITVKVLDRPGPPEGPLKVTGVTAEKCYLAWNPPLQDGGANISHYIIEKRETS 18540

Query: 1401  DVAELSISPSDNAV--VLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLD------SP 1452
              ++   +S    A+   +T LLPG EY+  V +V +     PL     T  +       P
Sbjct: 18541 RLSWTQVSTEVQALNYKVTKLLPGNEYIFRVMAVNKYGIGEPLESGPVTACNPYKPPGPP 18600

Query: 1453  TGIDFSDITANSFTVHWIAP----RATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTN 1508
             +  + S IT +S  V W  P       I GY +    +      + ++   +   + +T 
Sbjct: 18601 STPEVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDKEGVRWTKCNKKTLTDLRLRVTG 18660

Query: 1509  LTPGTEYVVSIVALN----GREESPLLIGQQSTV---SDVPRDLEVVAATPTSLLISWDA 1561
             LT G  Y   + A N    G    P +  +          P + +V   + +S+ ++W  
Sbjct: 18661 LTEGHSYEFRVAAENAAGVGEPSEPSVFYRACDALYPPGPPSNPKVTDTSRSSVSLAWSK 18720

Query: 1562  PAVTVRYYRITYGETGGNSPVQEFTVPGSKSTA-----------------TISGLKPGVD 1604
             P               G +PV+ + V   ++ A                 T++ LK   +
Sbjct: 18721 PIY------------DGGAPVKGYVVEVKEAAADEWTTCTPPTGLQGKQFTVTKLKENTE 18768

Query: 1605  YTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYR 1664
             Y   + A+   G    ++ P S+  +  I+ P      D++     V  L +S+ +   R
Sbjct: 18769 YNFRICAINSEGVGEPATLPGSVVAQERIEPPEIELDADLR----KVVVLRASATL---R 18821

Query: 1665  VTTTPKNGPGP----TKTKTAGPD--QTEMTIEGLQPTVEYVV-------SVYAQNPSGE 1711
             +  T K  P P     K +    D  Q E+T       ++ V        ++  +N SG 
Sbjct: 18822 LFVTIKGRPEPEVKWEKAEGILTDRAQIEVTSSFTMLVIDNVTRFDSGRYNLTLENNSGS 18881

Query: 1712  SQPLVQTAVTNI-DRPKGLAFTDVDVDSIKIAWESP----QGQVSRYRVTYSSPEDGIHE 1766
                 V   V +    P  L   +V  DS+ ++WE P      +++ Y V         + 
Sbjct: 18882 KTAFVNVRVLDSPSAPVNLTIREVKKDSVTLSWEPPLIDGGAKITNYIVEKRETTRKAYA 18941

Query: 1767  LFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPT----DLKFT 1822
                  +  + T  ++ L+ G  Y   V+A ++     P   T+   +  P      +   
Sbjct: 18942 TI-TNNCTKTTFRIENLQEGCSYYFRVLASNEYGIGLPAETTEPVKVSEPPLPPGRVTLV 19000

Query: 1823  QVTPTSLSAQWTPP----NVQLTGYRVRVTPK--EKTGPMKEINLAPDSSSVVVSGLMVA 1876
              VT  + + +W  P      ++TGY V +  K  EK     ++     +    +SGL   
Sbjct: 19001 DVTRNTATIKWEKPESDGGSKITGYVVEMQTKGSEKWSTCTQVK----TLEATISGLTAG 19056

Query: 1877  TKYEVSVYALKDTLTSRPAQ-GVVTTLENVS-------PPRRARVTDATETTITISWRTK 1928
              +Y   V A+ +   S P Q GV     ++        P     V    +  I + ++ +
Sbjct: 19057 EEYVFRVAAVNEKGRSDPRQLGVPVIARDIEIKPSVELPFHTFNVKAREQLKIDVPFKGR 19116

Query: 1929  TETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQ----PGTDYKIYLYTLNDNARS- 1983
              +    ++ D     GQT  + T      S T+T L        D   Y   ++++A S 
Sbjct: 19117 PQATVNWRKD-----GQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSNSAGSI 19171

Query: 1984  -SPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREV 2038
               P+ I        P  +R    + +S+ +SW PP      +I+ YI++ ++  S    +
Sbjct: 19172 TVPITIIVLDRPGPPGPIRIDEVSCDSITISWNPPEYDGGCQISNYIVEKKETTSTTWHI 19231

Query: 2039  VPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKS 2073
             V +     T   I  L  G+EY   V A     KS
Sbjct: 19232 VSQ-AVARTSIKIVRLTTGSEYQFRVCAENRYGKS 19265



 Score = 86.3 bits (212), Expect = 3e-16
 Identities = 342/1651 (20%), Positives = 590/1651 (35%), Gaps = 266/1651 (16%)

Query: 628   IQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISI 684
             + W+ P+    S I+ +I+  R    +  W++  I    +   I GL  G  Y+ ++I+ 
Sbjct: 8910  LNWSDPEDDGGSEITGFIIE-RKDAKMHTWRQP-IETERSKCDITGLLEGQEYKFRVIAK 8967

Query: 685   QQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWV--- 741
              ++G                PV    +        P      + TE T S+  + W    
Sbjct: 8968  NKFG-------------CGPPVEIGPILAVDPLGPPTSPERLTYTERTKSTITLDWKEPR 9014

Query: 742   -SASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQS 800
              +    + G+ +E    ++ D  +        TS  + +L   + Y   V  ++E GE  
Sbjct: 9015  SNGGSPIQGYIIEKRRHDKPDFERVNKRLCPTTSFLVENLDEHQMYEFRVKAVNEIGESE 9074

Query: 801   LILSTSQTTAPDAPPDPTVD---QVDDTSIVVRWSRP---QAPITGYRIVYSPSVEGSST 854
               L  +     D  P PT+     V   +I V+   P    A +TG  +   P +E S  
Sbjct: 9075  PSLPLNVVIQDDEVP-PTIKLRLSVRGDTIKVKAGEPVHIPADVTGLPM---PKIEWSKN 9130

Query: 855   E--LNLPETANSVTLSDLQPG-VQYNITI-YAVEENQESTPVVIQQETTGTPRS------ 904
             E  +  P  A  +T  ++     +  ++I  AV E++ +  V          R+      
Sbjct: 9131  ETVIEKPTDALQITKEEVSRSEAKTELSIPKAVREDKGTYTVTASNRLGSVFRNVHVEVY 9190

Query: 905   DTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPGEHGQRLPISRNT 960
             D    PR+L   ++      + W  P     S +T Y +D    +      + +    NT
Sbjct: 9191  DRPSPPRNLAVTDIKAESCYLTWDAPLDNGGSEITHYVIDKRDASRKKAEWEEVT---NT 9247

Query: 961   FAE----VTGLSPGVTYYFKV-----FAVSHGRESKPLTAQQTTKLDAPTNL-QFVNETD 1010
               E    +  L P   Y F+V     + +S   +S  +  Q   +L  P    + +  T 
Sbjct: 9248  AVEKRYGIWKLIPNGQYEFRVRAVNKYGISDECKSDKVVIQDPYRLPGPPGKPKVLARTK 9307

Query: 1011  STVLVRWTPP----RAQITGYRLTVGLTRRGQPRQY----------NVGPSVSKYPLRNL 1056
              ++LV WTPP     + ITGY     L +R +   Y           VG    ++ +  L
Sbjct: 9308  GSMLVSWTPPLDNGGSPITGY----WLEKREEGSPYWSRVSRAPITKVGLKGVEFNVPRL 9363

Query: 1057  QPASEYTVSLVAIKG------NQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPA 1110
                 +Y    +AI        ++ S           PG    P   + T+++I + W P 
Sbjct: 9364  LEGVKYQFRAMAINAAGIGPPSEPSDPEVAGDPIFPPGPPSCPEVKDKTKSSISLGWKPP 9423

Query: 1111  PRIGFKLGVRPSQG--GEAPREVTSD------------SGSIVVSGLTPGVEYVYTIQVL 1156
                  K G  P +G   E   E T+D            +   VV  L    +Y + ++ +
Sbjct: 9424  A----KDGGSPIKGYIVEMQEEGTTDWKRVNEPDKLITTCECVVPNLKELRKYRFRVKAV 9479

Query: 1157  RD-GQERDAPIVNKV-VTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPT- 1213
              + G+   +    ++  T +     + ++      ++  +  +   P +   R T   + 
Sbjct: 9480  NEAGESEPSDTTGEIPATDIQEEPEVFIDIGAQDCLVCKAGSQIRIPAVIKGRPTPKSSW 9539

Query: 1214  --NGQQGNSLEEVVH---ADQSSCTFDNLSPGL----------EYNVSVYTVKDDKES-- 1256
               +G+   ++++ VH    D    T +N S  +          +Y+++       K +  
Sbjct: 9540  EFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECKRSHTGKYSITAKNKAGQKTANC 9599

Query: 1257  -VPISDTIIPEVPQLTDLSFVDITDSSIGLRWTPLN---SSTIIGYRITVVAAGEGIPIF 1312
              V + D  +P  P+  DL   DIT  S  L W   +      I GY I      +G    
Sbjct: 9600  RVKVMD--VPGPPK--DLKVSDITRGSCRLSWKMPDDDGGDRIKGYVIEKRTI-DGKAWT 9654

Query: 1313  EDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAV-------PPPTDLR 1365
             +   D     + V  L     Y   V      G   P    Q+T          PP  L+
Sbjct: 9655  KVNPDCGSTTFVVPDLLSEQQYFFRVRAENRFGIGPPVETIQRTTARDPIYPPDPPIKLK 9714

Query: 1366  FTNIGPDTMRVTWAPPPS---IDLTNFLVR---YSPVK---------NEEDVAELSISPS 1410
                I  +T+ ++W PP +     +T+++V    + P           N+ DV EL  +  
Sbjct: 9715  IGLITKNTVHLSWKPPKNDGGSPVTHYIVECLAWDPTGTKKEAWRQCNKRDVEELQFTVE 9774

Query: 1411  DNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGL---DSPTGIDFSDI--TANSF 1465
             D       L+ G EY   V +V     S P            D P  ID  +        
Sbjct: 9775  D-------LVEGGEYEFRVKAVNAAGVSKPSATVGPCDCQRPDMPPSIDLKEFMEVEEGT 9827

Query: 1466  TVHWIA-----PRATITGYRIRH----------HPEHFSGRPREDR----VPHSRNSITL 1506
              V+ +A     P  T+T ++             +  H +    +D     +P SR S T 
Sbjct: 9828  NVNIVAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDT- 9886

Query: 1507  TNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAP---- 1562
                     Y ++ V   G     + +            ++  + +   + +SW  P    
Sbjct: 9887  ------GLYTITAVNNLGTASKEMRLNVLGRPGPPVGPIKFESVSADQMTLSWFPPKDDG 9940

Query: 1563  AVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRG-DSPAS 1621
                +  Y I   E    + V   + P  + T TI  L  G +Y   + A    G   P  
Sbjct: 9941  GSKITNYVIEKREANRKTWVHVSSEP-KECTYTIPKLLEGHEYVFRIMAQNKYGIGEPLD 9999

Query: 1622  SKP-ISINYRTEIDKPSQMQVTDVQDNSISVKW----LPSSSPVTGYRV---TTTPKN-- 1671
             S+P  + N  +    P +  V+ V  NS++V W        SPVTGY +    TT K   
Sbjct: 10000 SEPETARNLFSVPGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPVTGYWLEMKDTTSKRWK 10059

Query: 1672  --GPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSG---ESQPLVQTAVTNIDRP 1726
                  P K  T G       + GL    +Y   VYA N +G    S P       +   P
Sbjct: 10060 RVNRDPIKAMTLG---VSYKVTGLIEGSDYQFRVYAINAAGVGPASLPSDPATARDPIAP 10116

Query: 1727  KGLAF---TDVDVDSIKIAWESP----QGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAE 1779
              G  F   TD    S  + W  P      +V+ Y V Y   E+G  E     D E    +
Sbjct: 10117 PGPPFPKVTDWTKSSADLEWSPPLKDGGSKVTGYIVEYK--EEGKEEWEKGKDKEVRGTK 10174

Query: 1780  L--QGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTP-TSLSAQWTPP 1836
             L   GL+ G+ Y   V A++     +P  G  +  I    ++K   V+P   L A     
Sbjct: 10175 LVVTGLKEGAFYKFRVRAVNIAGIGEP--GEVTDVI----EMKDRLVSPDLQLDASVRDR 10228

Query: 1837  NVQLTGYRVRV-------TPKEKTGPMKEINLAPDSS--SVVVSGLMVATKYEVS---VY 1884
              V   G  +R+        P   T  M E  L  +++  +  +S  MV    + S   VY
Sbjct: 10229 IVVHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEATIETTAISSSMVIKNCQRSHQGVY 10288

Query: 1885  AL--KDTLTSRPAQGVVTTLENVSPPRRARVT-DATETTITISWRTKTE----TITGFQV 1937
             +L  K+    R    +V  L+   P     +  + T  +  ++W +  +     IT + +
Sbjct: 10289 SLLAKNEAGERKKTIIVDVLDVPGPVGTPFLAHNLTNESCKLTWFSPEDDGGSPITNYVI 10348

Query: 1938  DAVPANGQ--TPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLND-------NARSSPVVI 1988
             +   ++ +  TP+  T+    ++ T+ GL  G  Y   +   N            + V+ 
Sbjct: 10349 EKRESDRRAWTPVTYTVTR--QNATVQGLIQGKAYFFRIAAENSIGMGPFVETSEALVIR 10406

Query: 1989  DASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREVVPRPRP 2044
             +  T  + P +L     T N++ ++W PP+    + I  Y+++    G+     V     
Sbjct: 10407 EPITVPERPEDLEVKEVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEKFHKVTNDNL 10466

Query: 2045  GVTEATITGLEPGTEYTIYVIALKNNQKSEP 2075
                + T+ GL+ G  Y   V A+    + +P
Sbjct: 10467 LSRKYTVKGLKEGDTYEYRVSAVNIVGQGKP 10497



 Score = 84.3 bits (207), Expect = 1e-15
 Identities = 134/644 (20%), Positives = 244/644 (37%), Gaps = 79/644 (12%)

Query: 1512  GTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAP----AVTVR 1567
             G +Y++    + G +  P+ +            ++V   T     ++W  P       + 
Sbjct: 17388 GGQYILRASNVAGSKSFPVNVKVLDRPGPPEGPVQVTGVTSEKCSLTWSPPLQDGGSDIS 17447

Query: 1568  YYRITYGETGGNSPVQEFTVPGSK---STATISGLKPGVDYTITVYAVTGRG-DSPASSK 1623
             +Y +   ET   +    +TV  S+   ++  ++ L  G +Y   + AV   G   P  S 
Sbjct: 17448 HYVVEKRETSRLA----WTVVASEVVTNSLKVTKLLEGNEYVFRIMAVNKYGVGEPLESA 17503

Query: 1624  PISINYRTEID-KPSQMQVTDVQDNSISVKW-LPSS---SPVTGYRVTTTPKNGPGPTKT 1678
             P+ +     +   P  ++VT++  +S++V W  P S   S + GY V    ++G    K 
Sbjct: 17504 PVLMKNPFVLPGPPKSLEVTNIAKDSMTVCWNRPDSDGGSEIIGYIVEKRDRSGIRWIKC 17563

Query: 1679  KTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTA-------VTNIDRPKGLAF 1731
                      + + GL    EY   V A+N +G  +P   T        V     P     
Sbjct: 17564 NKRRITDLRLRVTGLTEDHEYEFRVSAENAAGVGEPSPATVYYKACDPVFKPGPPTNAHI 17623

Query: 1732  TDVDVDSIKIAWESP----QGQVSRYRVTYSSPEDGIHELFPAPDGEEDTA-ELQGLRPG 1786
              D   +SI +AW  P      ++  Y V     ++   ++     G   T  E+  L   
Sbjct: 17624 VDTTKNSITLAWGKPIYDGGSEILGYVVEICKADEEEWQIVTPQTGLRVTRFEISKLTEH 17683

Query: 1787  SEYTVSVVALHDDMESQPLIGT-QSTAIPAPTDLKFTQVTPT-SLSAQWTPPNVQLTGYR 1844
              EY + V AL+        +G  ++T++P     +     P   L ++     V   G  
Sbjct: 17684 QEYKIRVCALNK-------VGLGEATSVPGTVKPEDKLEAPELDLDSELRKGIVVRAGGS 17736

Query: 1845  VRVTPKEKTGPMKEINLAPD----SSSVVVSGLMVATKYEVS----------VYALKDTL 1890
              R+    K  P  EI  + +    +  V +   +  T+  +           +  L+++ 
Sbjct: 17737 ARIHIPFKGRPTPEITWSREEGEFTDKVQIEKGVNYTQLSIDNCDRNDAGKYILKLENSS 17796

Query: 1891  TSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKT----ETITGFQVDAVPANGQT 1946
              S+ A   V  L+   PP+   V +  + +  + W          +  + +D   +  + 
Sbjct: 17797 GSKSAFVTVKVLDTPGPPQNLAVKEVRKDSAFLVWEPPIIDGGAKVKNYVIDKRESTRKA 17856

Query: 1947  PIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPV-VIDASTAIDAPS-----NL 2000
                 + K    S+ +  L  G  Y   +   N+     PV  +DA  A + PS      L
Sbjct: 17857 YANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFGVGVPVETVDAVKAAEPPSPPGKVTL 17916

Query: 2001  RFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEP 2056
               ++ T  SL+  W+ P     +R+ GY+++ +  G+    +V   +  V  A +TGL  
Sbjct: 17917 TDVSQTSASLM--WEKPEHDGGSRVLGYVVEMQPKGTEKWSIVAESK--VCNAVVTGLSS 17972

Query: 2057  GTEYTIYVIALKNNQKSE------PLIGRKKTVQ---KTPFVTH 2091
             G EY   V A     KS+      P+I +  T+Q   K PF T+
Sbjct: 17973 GQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKLPFNTY 18016



 Score = 83.6 bits (205), Expect = 2e-15
 Identities = 320/1617 (19%), Positives = 567/1617 (35%), Gaps = 238/1617 (14%)

Query: 628   IQWNAPQPS---HISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISI 684
             + WN P  +    I+ YI++ R   +   W   +      +  +  LK G  Y+ ++ + 
Sbjct: 17037 LSWNPPLYTGGCQITNYIVQKRDTTTTV-WDVVSATVARTTLKVTKLKTGTEYQFRIFAE 17095

Query: 685   QQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSAS 744
              +YG       D        P+ +     E  P     AT+     I+  S V+ W    
Sbjct: 17096 NRYGQSFALESD--------PIVAQYPYKEPGPPGTPFATA-----ISKDSMVIQWHEPV 17142

Query: 745   DTVSGFRVEYELS-EEGDEPQYLDLPSTA---TSVNIPDLLPG-----RKYIVNVYQISE 795
             +      + Y L  +E +   +  +  T    T     +L  G     R Y  N+  + +
Sbjct: 17143 NNGGSPVIGYHLERKERNSILWTKVNKTIIHDTQFKAQNLEEGIEYEFRVYAENIVGVGK 17202

Query: 796   DGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ----APITGYRIVYSPSVEG 851
               + S          P   P+P +  V    I ++W++P     + ITGY +      +G
Sbjct: 17203 ASKNSECYVARDPCDPPGTPEPIM--VKRNEITLQWTKPVYDGGSMITGYIVEKRDLPDG 17260

Query: 852   ---SSTELNLPETANSVTLSDLQPGVQYNITIYA------VEENQESTPVVIQQETTGTP 902
                 ++  N+ ET    T+S L    +Y   + A      + +  +ST  +  ++    P
Sbjct: 17261 RWMKASFTNVIET--QFTVSGLTEDQRYEFRVIAKNAAGAISKPSDSTGPITAKDEVELP 17318

Query: 903   RSDTVPSPRDLQFVEVTDV-----------KVTIMWTPPESAVTGYRVDVIPVNLPGEHG 951
             R    P  RD   V   +              TI W   +  +              E  
Sbjct: 17319 RISMDPKFRDTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEI--------------EES 17364

Query: 952   QRLPISRNTFAEVTGLSPGVT-----YYFKVFAVSHGRESKPLTAQQTTKLDAPTN-LQF 1005
              R  I    F  +  +   +      Y  +   V+ G +S P+  +   +   P   +Q 
Sbjct: 17365 ARCEIKNTDFKALLIVKDAIRIDGGQYILRASNVA-GSKSFPVNVKVLDRPGPPEGPVQV 17423

Query: 1006  VNETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASE 1061
                T     + W+PP     + I+ Y +    T R            +   +  L   +E
Sbjct: 17424 TGVTSEKCSLTWSPPLQDGGSDISHYVVEKRETSRLAWTVVASEVVTNSLKVTKLLEGNE 17483

Query: 1062  YTVSLVAIK--GNQESPKATGVFTT---LQPGSSIPPYNTEVT---ETTIVITWTPAPR- 1112
             Y   ++A+   G  E  ++  V      + PG   PP + EVT   + ++ + W      
Sbjct: 17484 YVFRIMAVNKYGVGEPLESAPVLMKNPFVLPG---PPKSLEVTNIAKDSMTVCWNRPDSD 17540

Query: 1113  -----IGFKLGVRPSQGGE----APREVTSDSGSIVVSGLTPGVEYVYTIQVLRD---GQ 1160
                  IG+ +  R   G        R +T     + V+GLT   EY + +        G+
Sbjct: 17541 GGSEIIGYIVEKRDRSGIRWIKCNKRRITDLR--LRVTGLTEDHEYEFRVSAENAAGVGE 17598

Query: 1161  ERDAPIVNKVVTPL---SPPTNLHLEANPDTGVLTVSWERSTTP---DITGYRITTTPTN 1214
                A +  K   P+    PPTN H+  +     +T++W +       +I GY +     +
Sbjct: 17599 PSPATVYYKACDPVFKPGPPTNAHI-VDTTKNSITLAWGKPIYDGGSEILGYVVEICKAD 17657

Query: 1215  GQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDK--ESVPISDTIIPE----VP 1268
              ++   +        +      L+   EY + V  +      E+  +  T+ PE     P
Sbjct: 17658 EEEWQIVTPQTGLRVTRFEISKLTEHQEYKIRVCALNKVGLGEATSVPGTVKPEDKLEAP 17717

Query: 1269  QLTDLSFVDITDSSIGLRWTPLNSSTII--GYRITVVAAGEGIPIFEDFVDSSVGYYT-V 1325
             +L DL              + L    ++  G    +    +G P  E       G +T  
Sbjct: 17718 EL-DLD-------------SELRKGIVVRAGGSARIHIPFKGRPTPEITWSREEGEFTDK 17763

Query: 1326  TGLEPGIDYD---------------ISVITLINGGESAPTTLTQQTAVPPPTDLRFTNIG 1370
               +E G++Y                I  +   +G +SA  T+       PP +L    + 
Sbjct: 17764 VQIEKGVNYTQLSIDNCDRNDAGKYILKLENSSGSKSAFVTVKVLDTPGPPQNLAVKEVR 17823

Query: 1371  PDTMRVTWAPPPSIDLTNFLVRYSPVKNEED---VAELSISPSDNAVVLTNLLPGTEYVV 1427
              D+  + W PP  ID    +  Y   K E      A +S   S  +  + NL  G  Y  
Sbjct: 17824 KDSAFLVWEPP-IIDGGAKVKNYVIDKRESTRKAYANVSSKCSKTSFKVENLTEGAIYYF 17882

Query: 1428  SVSSVYEQHESTPLR---GRQKTGLDSPTG-IDFSDITANSFTVHWIAPR----ATITGY 1479
              V +  E     P+      +     SP G +  +D++  S ++ W  P     + + GY
Sbjct: 17883 RVMAENEFGVGVPVETVDAVKAAEPPSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLGY 17942

Query: 1480  RIRHHPEHFSGRPREDRVPHSRN-SITLTNLTPGTEYVVSIVALNGREES-PLLIGQQST 1537
              +   P+   G  +   V  S+  +  +T L+ G EY   + A N + +S P ++G    
Sbjct: 17943 VVEMQPK---GTEKWSIVAESKVCNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVI 17999

Query: 1538  VSDVPRDLEVVAATPTSLL-----ISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKS 1592
               D+     +     T  +     +  + P +      I++ + G   P+++ T    + 
Sbjct: 18000 AKDLTIQPSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDG--EPLKQTTRVNVEE 18057

Query: 1593  TAT--ISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKP-SQMQVTDVQDNSI 1649
             TAT  +  +K G       Y VT    +  +++ +S+    +   P   ++  +V  + +
Sbjct: 18058 TATSTVLHIKEGNKDDFGKYTVTATNSAGTATENLSVIVLEKPGPPVGPVRFDEVSADFV 18117

Query: 1650  SVKWLPSS----SPVTGYRV-----TTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYV 1700
              + W P +      ++ Y V     TTT  +    T  +T       + I  L+   EY 
Sbjct: 18118 VISWEPPAYTGGCQISNYIVEKRDTTTTTWHMVSATVARTT------IKITKLKTGTEYQ 18171

Query: 1701  VSVYAQNPSGESQPLVQTAVT-----NIDRPKGLAF-TDVDVDSIKIAWESPQGQVSRYR 1754
               ++A+N  G+S PL   AV          P G  F T +  D + + W  P        
Sbjct: 18172 FRIFAENRYGKSAPLDSKAVIVQYPFKEPGPPGTPFVTSISKDQMLVQWHEPVNDGGTKI 18231

Query: 1755  VTYSSPEDGIHELF-------PAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIG 1807
             + Y   +   + +        P  D +  T    GL  G EY   V A +     +P   
Sbjct: 18232 IGYHLEQKEKNSILWVKLNKTPIQDTKFKTT---GLDEGLEYEFKVSAENIVGIGKPSKV 18288

Query: 1808  TQSTAIPAPTDL----KFTQVTPTSLSAQWTPP----NVQLTGYRVRVTPKEKTGPMKEI 1859
             ++      P D     +   +T  +++ +W  P      ++TGY V          MK  
Sbjct: 18289 SECFVARDPCDPPGRPEAIVITRNNVTLKWKKPAYDGGSKITGYIVEKKDLPDGRWMKAS 18348

Query: 1860  NLAPDSSSVVVSGLMVATKYEVSVYALKDTLT-SRPAQ--GVVTTLENVSPPRRAR---- 1912
                   +   VSGL+   +YE  V A       S P+   G +T  + +  P  +     
Sbjct: 18349 FTNVLETEFTVSGLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARDEIDAPNASLDPKY 18408

Query: 1913  ----VTDATET-TITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQP- 1966
                 V  A ET  +    R K      +  D      +T  +  IK  ++  T+      
Sbjct: 18409 KDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELE-ETAARMEIKSTIQKTTLVVKDCI 18467

Query: 1967  GTDYKIYLYTLND--NARSSPVVIDASTAIDAPSN-LRFLATTPNSLLVSWQPPR----A 2019
              TD   Y+  L++    +S P+ +        P   L+    T     ++W PP     A
Sbjct: 18468 RTDGGQYILKLSNVGGTKSIPITVKVLDRPGPPEGPLKVTGVTAEKCYLAWNPPLQDGGA 18527

Query: 2020  RITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPL 2076
              I+ YII+  +        V      +    +T L PG EY   V+A+      EPL
Sbjct: 18528 NISHYIIEKRETSRLSWTQVSTEVQALNYK-VTKLLPGNEYIFRVMAVNKYGIGEPL 18583



 Score = 82.4 bits (202), Expect = 5e-15
 Identities = 130/589 (22%), Positives = 217/589 (36%), Gaps = 70/589 (11%)

Query: 1596  ISGLKPGVDYTITVYAVTGRG-DSPASSKPI-SINYRTEIDKPSQMQVTDVQDNSISVKW 1653
             ++ L  G +YT  + AV   G   P  S+P+ + N     D P   +VT V  +S+ V W
Sbjct: 16393 VTKLLEGNEYTFRIMAVNKYGVGEPLESEPVVAKNPFVVPDAPKAPEVTTVTKDSMIVVW 16452

Query: 1654  -LPSS---SPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPS 1709
               P+S   S + GY +    K G   T+       +  + + GL    +Y   V A+N +
Sbjct: 16453 ERPASDGGSEILGYVLEKRDKEGIRWTRCHKRLIGELRLRVTGLIENHDYEFRVSAENAA 16512

Query: 1710  GESQPLVQTA-------VTNIDRPKGLAFTDVDVDSIKIAWESP----QGQVSRYRVTYS 1758
             G S+P   +A       +     P      D+   S+ ++W  P      ++  Y V   
Sbjct: 16513 GLSEPSPPSAYQKACDPIYKPGPPNNPKVIDITRSSVFLSWSKPIYDGGCEIQGYIVEKC 16572

Query: 1759  SPEDGIHELFPAPDGEEDT-AELQGLRPGSEYTVSVVAL-------HDDMESQPLIGTQS 1810
                 G   +   P G   T  E++ L    EY   + A+       H D+    ++  + 
Sbjct: 16573 DVSVGEWTMCTPPTGINKTNIEVEKLLEKHEYNFRICAINKAGVGEHADVPGPIIVEEKL 16632

Query: 1811  TAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEK----TGPMKEINLAPDSS 1866
              A     DL+  ++                   + R TP+ K     G +++  +   +S
Sbjct: 16633 EAPDIDLDLELRKIINIRAGGSLR----LFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTS 16688

Query: 1867  SVVVSGLMVATKYEVSVY--ALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITIS 1924
             S     L    +Y+   Y   L+++  ++ A   V  L+  SPP   +VT+ T+ +++I+
Sbjct: 16689 SFTSLVLDNVNRYDSGKYTLTLENSSGTKSAFVTVRVLDTPSPPVNLKVTEITKDSVSIT 16748

Query: 1925  WRTKT----ETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDN 1980
             W          I  + V+   A  ++           S+ I  LQ G  Y   +   N+ 
Sbjct: 16749 WEPPLLDGGSKIKNYIVEKREATRKSYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAENEY 16808

Query: 1981  ARSSPV----VIDASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPG 2032
                 P      I  +     P  +     T NS+ +SW  P     ++I  YI++ +   
Sbjct: 16809 GIGLPAQTADPIKVAEVPQPPGKITVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKH 16868

Query: 2033  SPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQKTPFVTHP 2092
             S       R +    +A IT L  G EY   V+A+    +S+P       V K   V  P
Sbjct: 16869 SEKWSECARVKS--LQAVITNLTQGEEYLFRVVAVNEKGRSDPRSLAVPIVAK-DLVIEP 16925

Query: 2093  GYDTGNGIQLPGTSGQQPSVGQQMIFEEHGFRRTTPPTTATPIRHRPRP 2141
                       P  S     VGQ +  E              PI  RP+P
Sbjct: 16926 DVK-------PAFSSYSVQVGQDLKIE-------------VPISGRPKP 16954



 Score = 78.2 bits (191), Expect = 9e-14
 Identities = 285/1428 (19%), Positives = 490/1428 (34%), Gaps = 237/1428 (16%)

Query: 690   QEVTRFDFTTTSTST---------------PVTSNTVTGET-------------TPFSPL 721
             ++  R +F TT+TST               P+T+  + GE               P  P+
Sbjct: 14802 KQTQRVNFETTATSTILNINECVRSDSGPYPLTARNIVGEVGDVITIQVHDIPGPPTGPI 14861

Query: 722   VATSESVTEITASSFVVSWVSASDT----VSGFRVEYELSEEGDEPQYLDLPSTA--TSV 775
                     E+++     SW    +     +S + VE     + D   +++L +T   T+ 
Sbjct: 14862 -----KFDEVSSDFVTFSWDPPENDGGVPISNYVVEMR---QTDSTTWVELATTVIRTTY 14913

Query: 776   NIPDLLPGRKYIVNV-----YQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVR 830
                 L  G +Y   V     Y +      + I++      P  P  P V  V   S+ + 
Sbjct: 14914 KATRLTTGLEYQFRVKAQNRYGVGPGITSACIVANYPFKVPGPPGTPQVTAVTKDSMTIS 14973

Query: 831   WSRPQA----PITGYRIVYSPSVEGSSTELNLPETANSVTL-------SDLQPGVQYNIT 879
             W  P +    PI GY       VE       L +T +   +       S L  G+ Y   
Sbjct: 14974 WHEPLSDGGSPILGYH------VERKERNGILWQTVSKALVPGNIFKSSGLTDGIAYEFR 15027

Query: 880   IYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESA----VT 935
             + A     +S P    +        D    P  L     T   VT+ W  PE      +T
Sbjct: 15028 VIAENMAGKSKPSKPSEPMLALDPIDPPGKPVPLNITRHT---VTLKWAKPEYTGGFKIT 15084

Query: 936   GYRVDVIPVNLPGEHGQRLPISR---NTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQ 992
              Y V+    +LP     +   S    N F  V+GL+    Y F+V A +      P +  
Sbjct: 15085 SYIVE--KRDLPNGRWLKANFSNILENEFT-VSGLTEDAAYEFRVIAKNAAGAISPPSEP 15141

Query: 993   QTT-----KLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPS 1047
                      ++AP     V   D+ +L            +RL   ++ R  P        
Sbjct: 15142 SDAITCRDDVEAPKIKVDVKFKDTVILKAGE-------AFRLEADVSGRPPPTMEWSKDG 15194

Query: 1048  VSKYPLRNLQ-PASEYTVSLVAIKGNQESPKATGVFTTLQPGSSI-------------PP 1093
                     L+   ++++ +LV  K +          T   PG                PP
Sbjct: 15195 KELEGTAKLEIKIADFSTNLVN-KDSTRRDSGAYTLTATNPGGFAKHIFNVKVLDRPGPP 15253

Query: 1094  YN----TEVTETTIVITW-TPAPRIGFKLGVRPSQGGEAPREVTSDSGSIV------VSG 1142
                   TEVT    V++W  P    G K+     Q  E  R   ++  S V      V+ 
Sbjct: 15254 EGPLAVTEVTSEKCVLSWFPPLDDGGAKIDHYIVQKRETSRLAWTNVASEVQVTKLKVTK 15313

Query: 1143  LTPGVEYVYTIQVLRD---GQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLT-----VS 1194
             L  G EY++ +  +     G+  ++  V   V P  PP       NP+   +T     V 
Sbjct: 15314 LLKGNEYIFRVMAVNKYGVGEPLESEPV-LAVNPYGPPDP---PKNPEVTTITKDSMVVC 15369

Query: 1195  WERSTTP---DITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVK 1251
             W    +    +I  Y +      GQ+     +    D        L+ G EY   +    
Sbjct: 15370 WGHPDSDGGSEIINYIVERRDKAGQRWIKCNKKTLTDLRY-KVSGLTEGHEYEFRIMAEN 15428

Query: 1252  DDKESVP--------ISDTIIPEVPQLTDLSFVDITDSSIGLRWT-PL--NSSTIIGYRI 1300
                 S P          DT+    P   +   +D + SSI + W  P+    S I GY +
Sbjct: 15429 AAGISAPSPTSPFYKACDTVFKPGPP-GNPRVLDTSRSSISIAWNKPIYDGGSEITGYMV 15487

Query: 1301  TVVAAGEGI-PIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAP-----TTLTQ 1354
              +    E    I           YT+TGL    +Y I +  + + G   P     T   +
Sbjct: 15488 EIALPEEDEWQIVTPPAGLKATSYTITGLTENQEYKIRIYAMNSEGLGEPALVPGTPKAE 15547

Query: 1355  QTAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNE------------EDV 1402
                +PP  +L       D  +V      +I     L  + P+K              E +
Sbjct: 15548 DRMLPPEIEL-----DADLRKVV-----TIRACCTLRLFVPIKGRPAPEVKWARDHGESL 15597

Query: 1403  AELSISPSDNAVVL----TNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFS 1458
              + SI  + +  +L     N     +Y+++V +     +S  +  R       P  +   
Sbjct: 15598 DKASIESTSSYTLLIVGNVNRFDSGKYILTVENS-SGSKSAFVNVRVLDTPGPPQDLKVK 15656

Query: 1459  DITANSFTVHWIAPRATITGYRIRHH--PEHFSGRPREDRVPHS--RNSITLTNLTPGTE 1514
             ++T  S T+ W  P     G +I+++   +  S R     V  +  + S  +  L  G  
Sbjct: 15657 EVTKTSVTLTWDPPLLD-GGSKIKNYIVEKRESTRKAYSTVATNCHKTSWKVDQLQEGCS 15715

Query: 1515  YVVSIVALNGREES-PLLIGQQSTVSD---VPRDLEVVAATPTSLLISWDAP----AVTV 1566
             Y   ++A N      P    +    S+    P  + ++  T  S+ +SW+ P       +
Sbjct: 15716 YYFRVLAENEYGIGLPAETAESVKASERPLPPGKITLMDVTRNSVSLSWEKPEHDGGSRI 15775

Query: 1567  RYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPIS 1626
               Y +     G +      TV  ++  ATI+GL  G +Y+  V A   +G S      + 
Sbjct: 15776 LGYIVEMQTKGSDKWATCATVKVTE--ATITGLIQGEEYSFRVSAQNEKGISDPRQLSVP 15833

Query: 1627  INYRTEIDKPS------QMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKT 1680
             +  +  +  P+         V   +D  + V ++   +P   +     P       +T  
Sbjct: 15834 VIAKDLVIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLK-----QTTR 15888

Query: 1681  AGPDQTE----MTIEGL--QPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKG--LAFT 1732
                + TE    +TI+    +    YVV +   N +GE+   +   V +   P    +   
Sbjct: 15889 VNAESTENNSLLTIKDACREDVGHYVVKL--TNSAGEAIETLNVIVLDKPGPPTGPVKMD 15946

Query: 1733  DVDVDSIKIAWESPQ----GQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSE 1788
             +V  DSI ++W  P+      ++ Y V          ++  A      T +   L+ G E
Sbjct: 15947 EVTADSITLSWGPPKYDGGSSINNYIVEKRDTSTTTWQIVSATVART-TIKACRLKTGCE 16005

Query: 1789  YTVSVVALH-----DDMESQPLIGTQSTAIPAPTDLKFTQVTPT-SLSAQWTPP----NV 1838
             Y   + A +       + S+P +      +P P       ++   S+  QW  P      
Sbjct: 16006 YQFRIAAENRYGKSTYLNSEPTVAQYPFKVPGPPGTPVVTLSSRDSMEVQWNEPISDGGS 16065

Query: 1839  QLTGYRVRVTPKEKTGPM-KEINLAP-DSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQ 1896
             ++ GY +    KE+   +  ++N  P   +    +GL    +YE  V A       +P++
Sbjct: 16066 RVIGYHLE--RKERNSILWVKLNKTPIPQTKFKTTGLEEGVEYEFRVSAENIVGIGKPSK 16123

Query: 1897  --GVVTTLENVSPPRRARVTDATETTITISWRTKT----ETITGFQVD 1938
                     +   PP R      T  ++T+ W+  T      ITG+ V+
Sbjct: 16124 VSECYVARDPCDPPGRPEAIIVTRNSVTLQWKKPTYDGGSKITGYIVE 16171



 Score = 75.1 bits (183), Expect = 8e-13
 Identities = 286/1351 (21%), Positives = 472/1351 (34%), Gaps = 234/1351 (17%)

Query: 797   GEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ----APITGYRIVYSPSVEGS 852
             G +++ +       P  P D  V ++   S  + W  P     + IT Y +         
Sbjct: 10991 GSKTVSVKVLVLDKPGPPRDLEVSEIRKDSCYLTWKEPLDDGGSVITNYVVERRDVASAQ 11050

Query: 853   STELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRD 912
              + L+      S     L  G QY   + A  +      V   +             P+D
Sbjct: 11051 WSPLSATSKKKSHFAKHLNEGNQYLFRVAAENQYGRGPFVETPKPIKALDPLHPPGPPKD 11110

Query: 913   LQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPVNLPGEHGQRLPISRNTFAE----V 964
             L  V+V   +V+++W  P+    S +TGY V+        E G +  I   T       V
Sbjct: 11111 LHHVDVDKTEVSLVWNKPDRDGGSPITGYLVEY------QEEGTQDWIKFKTVTNLECVV 11164

Query: 965   TGLSPGVTYYFKVFA---VSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPR 1021
             TGL  G TY F+V A   V  G     +  +   KL  P+    V   +  V+   T  R
Sbjct: 11165 TGLQQGKTYRFRVKAENIVGLGLPDTTIPIECQEKLVPPSVELDVKLIEGLVVKAGTTVR 11224

Query: 1022  --AQITGYRL-TVGLTRRGQPRQYNVGPSV------SKYPLRNL--QPASEYTVSLVAIK 1070
               A I G  + T   T  G   + +   +V      S   ++N   +   EY +++    
Sbjct: 11225 FPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEYQITV---- 11280

Query: 1071  GNQESPKATGVFTTLQ--PGSSIPPYNT-EVTETTIVITWTPAPRIGFKLGVRPSQGGEA 1127
              N    K   V  T+   PG    P N  +VT   + I+W P           P   G +
Sbjct: 11281 SNAAGSKTVAVHLTVLDVPGPPTGPINILDVTPEHMTISWQP-----------PKDDGGS 11329

Query: 1128  P--------REVTSDSGSIVVSG----------LTPGVEYVYTIQV---LRDGQERDA-P 1165
             P        ++   D+  +V SG          L  G EYV+ ++    +  G   D+ P
Sbjct: 11330 PVINYIVEKQDTRKDTWGVVSSGSSKTKLKIPHLQKGCEYVFRVRAENKIGVGPPLDSTP 11389

Query: 1166  IVNK-VVTPLSPPTNLHLEANPDTGVLTVSWERSTTPD---ITGY------------RIT 1209
              V K   +P SPP    +  +      TVSW    +     ITGY            R+ 
Sbjct: 11390 TVAKHKFSPPSPPGK-PVVTDITENAATVSWTLPKSDGGSPITGYYMERREVTGKWVRVN 11448

Query: 1210  TTP--------TNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISD 1261
              TP        T   +GN+ E  V A+       NL+   + + S   +K  +   PI  
Sbjct: 11449 KTPIADLKFRVTGLYEGNTYEFRVFAE-------NLAGLSKPSPSSDPIKACR---PIKP 11498

Query: 1262  TIIPEVPQLTDLSFVDITDSSIGLRWT-PLNS--STIIGYRITVVAAG--EGIPIFEDFV 1316
                P  P+L D S       +  L WT PL+   S I+GY +     G  +   I +D +
Sbjct: 11499 PGPPINPKLKDKS-----RETADLVWTKPLSDGGSPILGYVVECQKPGTAQWNRINKDEL 11553

Query: 1317  DSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAV-----PPPTDLRFTNIGP 1371
                  +  V GL  G +Y   +      GE  P  L +         PP  +L  T    
Sbjct: 11554 IRQCAF-RVPGLIEGNEYRFRIKAANIVGEGEPRELAESVIAKDILHPPEVELDVTCRDV 11612

Query: 1372  DTMRVTWA----------PPPSIDLTN---FLVRYSPVKNEEDV--AELSISPSDNAVVL 1416
              T+RV             P P I  T     LVR   V   +D+   EL I  +  A   
Sbjct: 11613 ITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRA--- 11669

Query: 1417  TNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSP---TGIDFSDITANSFTVHWIAPR 1473
                    +Y++S  +     + + +       LD P     +  +++T  + T+ W  P 
Sbjct: 11670 ----DHGKYIISAKNSSGHAQGSAI----VNVLDRPGPCQNLKVTNVTKENCTISWENPL 11721

Query: 1474  ----ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNG----- 1524
                 + IT + + +   +  G          R  +   NL    EY   + A N      
Sbjct: 11722 DNGGSEITNFIVEYRKPNQKGWSIVASDVTKR--LIKANLLANNEYYFRVCAENKVGVGP 11779

Query: 1525  --REESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYG---ETGGN 1579
                 ++P+L          P +L +     T + + W  P        ++Y       G+
Sbjct: 11780 TIETKTPILAINPIDRPGEPENLHIADKGKTFVYLKWRRPDYDGGSPNLSYHVERRLKGS 11839

Query: 1580  SPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASS--KPISINYRTEIDKPS 1637
                +       K T  +  +   V+  I  + V  + +   S   K   +  + ++ KP 
Sbjct: 11840 DDWERVHKGSIKETHYM--VDRCVENQIYEFRVQTKNEGGESDWVKTEEVVVKEDLQKP- 11896

Query: 1638  QMQVTDVQDNSIS-VKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMT------I 1690
                   V D  +S V  + +   +   R+    +  P P    T   D T++T      I
Sbjct: 11897 ------VLDLKLSGVLTVKAGDTI---RLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKI 11947

Query: 1691  EGLQPTVEYVVSVYAQNPSGE--------SQPLVQTAVTNI-DRP---KGLAFTDVDVDS 1738
             +    + ++ ++   ++  G+        +   V  A  N+ D+P   + L   DV  D 
Sbjct: 11948 DTRADSSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATVNVLDKPGPVRNLKIVDVSSDR 12007

Query: 1739  IKIAWESPQG----QVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSV- 1793
               + W+ P+     ++  Y +     +  +   + A      T   + L  G+EY   V 
Sbjct: 12008 CTVCWDPPEDDGGCEIQNYILEKCETKRMVWSTYSATVLTPGTTVTR-LIEGNEYIFRVR 12066

Query: 1794  ----VALHDDMESQPLIGTQSTAIPA-PTDLKFTQVTPTSLSAQWTPPNVQ----LTGYR 1844
                 +      ES+P+I       P  P   + T+V+   ++  W PP       +TGY 
Sbjct: 12067 AENKIGTGPPTESKPVIAKTKYDKPGRPDPPEVTKVSKEEMTVVWNPPEYDGGKSITGYF 12126

Query: 1845  VRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKD------TLTSRPAQGV 1898
             +    K  T  +     A     + V  L+   +Y+  V A  +      +L SRP    
Sbjct: 12127 LEKKEKHSTRWVPVNKSAIPERRMKVQNLLPDHEYQFRVKAENEIGIGEPSLPSRPVVAK 12186

Query: 1899  VTTLENVSPPRRARVTDATETTITISWRTKT----ETITGFQV-------DAVPANGQTP 1947
                +E   PP   RV D T+ +IT+ W          I G+ V       DA P  G   
Sbjct: 12187 -DPIEPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAPIIGYVVEMRPKIADASPDEGWKR 12245

Query: 1948  IQRTIKPDVRSYTITGLQPGTDYKIYLYTLN 1978
                  +   + +T+T L    +Y+  +   N
Sbjct: 12246 CNAAAQLVRKEFTVTSLDENQEYEFRVCAQN 12276



 Score = 74.3 bits (181), Expect = 1e-12
 Identities = 276/1411 (19%), Positives = 484/1411 (34%), Gaps = 227/1411 (16%)

Query: 814   PPDPTVD--QVDDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTL 867
             PP P  D   +D  +  + W  P     + IT Y +       G         T  S  +
Sbjct: 12689 PPQPPFDISDIDADACSLSWHIPLEDGGSNITNYIVEKCDVSRGDWVTALASVTKTSCRV 12748

Query: 868   SDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPS-PRDLQFVEVTDVKVTIM 926
               L PG +Y   + A      S P+   +     P    VPS P++ +  +V    + + 
Sbjct: 12749 GKLIPGQEYIFRVRAENRFGISEPLTSPKMVAQFPFG--VPSEPKNARVTKVNKDCIFVA 12806

Query: 927   WTPPES----AVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSH 982
             W  P+S     + GY ++    N          + R+T     GL  G+ Y F+++A++ 
Sbjct: 12807 WDRPDSDGGSPIIGYLIERKERNSLLWVKANDTLVRSTEYPCAGLVEGLEYSFRIYALNK 12866

Query: 983   GRESKPL--TAQQTTKL--DAPTNLQFVNETDSTVLVRWTPPR----AQITGYRLTVGLT 1034
                S P   T   T ++  D P   + ++ T STV + W  P+    ++I GY +     
Sbjct: 12867 AGSSPPSKPTEYVTARMPVDPPGKPEVIDVTKSTVSLIWARPKHDGGSKIIGYFVEACKL 12926

Query: 1035  RRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPY 1094
                +  + N  P        +  P  EYT + +  K   +          + P S     
Sbjct: 12927 PGDKWVRCNTAP--------HQIPQEEYTATGLEEKAQYQFRAIARTAVNISPPS----- 12973

Query: 1095  NTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQ 1154
               E ++   ++     PRI   + ++     +A   V  D+   V     P V +     
Sbjct: 12974 --EPSDPVTILAENVPPRIDLSVAMKSLLTVKAGTNVCLDA--TVFGKPMPTVSWKKDGT 13029

Query: 1155  VLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTN 1214
             +L+  +     +   + T       L      D+G  T++ E S+       ++      
Sbjct: 13030 LLKPAEGIKMAMQRNLCT-----LELFSVNRKDSGDYTITAENSSGSKSATIKLKVLDKP 13084

Query: 1215  GQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYT--VKDDKESVPISDTIIPEVPQLTD 1272
             G   +     +++D++  +++   P LE   S  T  + D +E      T  P   Q++ 
Sbjct: 13085 GPPASVKINKMYSDRAMLSWE---PPLEDGGSEITNYIVDKRE------TSRPNWAQVS- 13134

Query: 1273  LSFVDITDSSIGLRWTPLNSSTIIG--YRITVVAA---GEGIPIFEDFVDSSVGYYTVTG 1327
              + V IT  S+           I G  Y+  + A    G G P+F               
Sbjct: 13135 -ATVPITSCSV--------EKLIEGHEYQFRICAENKYGVGDPVFT-------------- 13171

Query: 1328  LEPGIDYDISVITLINGGESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAPPPS---I 1384
              EP I               A           PP     +NI  D M V+W PP      
Sbjct: 13172 -EPAI---------------AKNPYDPPGRCDPPV---ISNITKDHMTVSWKPPADDGGS 13212

Query: 1385  DLTNFLV--RYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLR 1442
              +T +L+  R +   N   V    I   +  +  T L  GTEY   V+++ +     P  
Sbjct: 13213 PITGYLLEKRETQAVNWTKVNRKPII--ERTLKATGLQEGTEYEFRVTAINKAGPGKPSD 13270

Query: 1443  GRQKTGLDSP-------TGIDFSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGR 1491
               +      P             D T +S ++ W  P     + I GY +          
Sbjct: 13271 ASKAAYARDPQYPPGPPAFPKVYDTTRSSVSLSWGKPAYDGGSPIIGYLVEVKRADSDNW 13330

Query: 1492  PREDRVPH-SRNSITLTNLTPGTEYVVSIVALNGREES-PLLIGQQSTVSDV--PRDLEV 1547
              R +   +  +    +T L   T+Y   + A+N    S P  +  +    D+  P + E+
Sbjct: 13331 VRCNLPQNLQKTRFEVTGLMEDTQYQFRVYAVNKIGYSDPSDVPDKHYPKDILIPPEGEL 13390

Query: 1548  VAATPTSLLISWDAPAVTVRYY---------RITYGETGGNSPVQEFTVPGSKSTATISG 1598
              A    +L++      VT+R Y         +IT+ +   N   +      S    T   
Sbjct: 13391 DADLRKTLILR---AGVTMRLYVPVKGRPPPKITWSKPNVNLRDRIGLDIKSTDFDTFLR 13447

Query: 1599  LKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLP--- 1655
              +    Y    Y +T           I +        P  + V ++  +S  V W P   
Sbjct: 13448 CENVNKYDAGKYILTLENSCGKKEYTIVVKVLDTPGPPVNVTVKEISKDSAYVTWEPPII 13507

Query: 1656  -SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQP 1714
                SP+  Y V            T T    +T   +  L+    Y   V+A+N  G   P
Sbjct: 13508 DGGSPIINYVVQKRDAERKS-WSTVTTECSKTSFRVANLEEGKSYFFRVFAENEYGIGDP 13566

Query: 1715  LVQTAVTNIDRPKG----LAFTDVDVDSIKIAWESPQG----QVSRYRVTYSSPEDGIHE 1766
                       +  G    L    V   S  I W+ P      ++  Y V + + E+    
Sbjct: 13567 GETRDAVKASQTPGPVVDLKVRSVSKSSCSIGWKKPHSDGGSRIIGYVVDFLTEENKWQR 13626

Query: 1767  LFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTP 1826
             +  +   +    +L     G EYT  V A +++ E  P        + A  D     V  
Sbjct: 13627 VMKSLSLQYSAKDLT---EGKEYTFRVSAENENGEGTP----SEITVVARDD-----VVA 13674

Query: 1827  TSLSAQWTPPNVQL----TGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVS 1882
               L  +  P    L    + +R+++  K K  P        D        L   T+  V 
Sbjct: 13675 PDLDLKGLPDLCYLAKENSNFRLKIPIKGKPAPSVSWKKGEDP-------LATDTRVSVE 13727

Query: 1883  VYALKDTLTSRPAQ----GVVT-TLENVSPPRRARVT-----------------DATETT 1920
               A+  TL     Q    G  T TL+NV+  +   ++                 + T   
Sbjct: 13728 SSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKEGTISIKVVGKPGIPTGPIKFDEVTAEA 13787

Query: 1921  ITISWRTKTET----ITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYL-- 1974
             +T+ W    +     IT + ++   +     +         ++ +T L  G +Y   +  
Sbjct: 13788 MTLKWAPPKDDGGSEITNYILEKRDSVNNKWVTCASAVQKTTFRVTRLHEGMEYTFRVSA 13847

Query: 1975  ---YTLNDNARSSPVVIDASTAI-DAPSNLRFLATTPNSLLVSWQPPR----ARITGYII 2026
                Y + +  +S P+V      + DAP     +    +S+ ++W  P+    + ITGY +
Sbjct: 13848 ENKYGVGEGLKSEPIVARHPFDVPDAPPPPNIVDVRHDSVSLTWTDPKKTGGSPITGYHL 13907

Query: 2027  KYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIAL------KNNQKSEPLI--- 2077
             ++++  S   +   +    + +  +TGL  G EY   V+A+      K +  SEP++   
Sbjct: 13908 EFKERNSLLWKRANKTPIRMRDFKVTGLTEGLEYEFRVMAINLAGVGKPSLPSEPVVALD 13967

Query: 2078  -----GRKKTV-----QKTPFVTHPGYDTGN 2098
                  G+ + +       T   T P YD G+
Sbjct: 13968 PIDPPGKPEVINITRNSVTLIWTEPKYDGGH 13998



 Score = 72.8 bits (177), Expect = 4e-12
 Identities = 334/1588 (21%), Positives = 550/1588 (34%), Gaps = 285/1588 (17%)

Query: 828   VVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAV 883
             ++ WS P+    + ITG+ I+     +  +    +    +   ++ L  G +Y   + A 
Sbjct: 8909  LLNWSDPEDDGGSEITGF-IIERKDAKMHTWRQPIETERSKCDITGLLEGQEYKFRVIAK 8967

Query: 884   EENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPES----AVTGYRV 939
              +     PV I       P      SP  L + E T   +T+ W  P S     + GY +
Sbjct: 8968  NKFGCGPPVEIGPILAVDPLGPPT-SPERLTYTERTKSTITLDWKEPRSNGGSPIQGYII 9026

Query: 940   DVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLD- 998
             +    + P        +   T   V  L     Y F+V AV+   ES+P         D 
Sbjct: 9027  EKRRHDKPDFERVNKRLCPTTSFLVENLDEHQMYEFRVKAVNEIGESEPSLPLNVVIQDD 9086

Query: 999   --APTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPR-QYNVGPSVSKYPLRN 1055
                PT    ++    T+ V+   P        +   +T    P+ +++   +V + P   
Sbjct: 9087  EVPPTIKLRLSVRGDTIKVKAGEP------VHIPADVTGLPMPKIEWSKNETVIEKPTDA 9140

Query: 1056  LQPASEYTVSLVAIKGNQESPKAT----GVFTTLQP---GSSI------------PPYNT 1096
             LQ   E  VS    K     PKA     G +T       GS              PP N 
Sbjct: 9141  LQITKE-EVSRSEAKTELSIPKAVREDKGTYTVTASNRLGSVFRNVHVEVYDRPSPPRNL 9199

Query: 1097  EVTET---TIVITW-TPAPRIGFKLGVRPSQGGEAPR------EVTSDSGS--IVVSGLT 1144
              VT+    +  +TW  P    G ++        +A R      EVT+ +      +  L 
Sbjct: 9200  AVTDIKAESCYLTWDAPLDNGGSEITHYVIDKRDASRKKAEWEEVTNTAVEKRYGIWKLI 9259

Query: 1145  PGVEYVYTIQVLR-----DGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSW---- 1195
             P  +Y + ++ +      D  + D  ++        PP    + A    G + VSW    
Sbjct: 9260  PNGQYEFRVRAVNKYGISDECKSDKVVIQDPYRLPGPPGKPKVLARTK-GSMLVSWTPPL 9318

Query: 1196  ERSTTPDITGYRITTTPTNGQQGNSLEE--VVHADQSSCTFD--NLSPGLEYNVSVYTVK 1251
             +   +P ITGY +          + +    +         F+   L  G++Y      + 
Sbjct: 9319  DNGGSP-ITGYWLEKREEGSPYWSRVSRAPITKVGLKGVEFNVPRLLEGVKYQFRAMAIN 9377

Query: 1252  --------DDKESVPISDTIIPEVPQLTDLSFVDITDSSIGLRWTPL---NSSTIIGYRI 1300
                     +  +     D I P  P        D T SSI L W P      S I GY +
Sbjct: 9378  AAGIGPPSEPSDPEVAGDPIFPPGPPSCP-EVKDKTKSSISLGWKPPAKDGGSPIKGYIV 9436

Query: 1301  TVVAAG--EGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAV 1358
              +   G  +   + E     +     V  L+    Y   V  +   GES P+  T +   
Sbjct: 9437  EMQEEGTTDWKRVNEPDKLITTCECVVPNLKELRKYRFRVKAVNEAGESEPSDTTGEI-- 9494

Query: 1359  PPPTDLR-----FTNIGPDTMRVTWA-------------PPPS----IDLTNFLVRYSPV 1396
              P TD++     F +IG     V  A             P P      D          V
Sbjct: 9495  -PATDIQEEPEVFIDIGAQDCLVCKAGSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGV 9553

Query: 1397  KNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTP-LRGRQKTGLDSPTGI 1455
              +  + A+L  + + + +++           S+++  +  + T   R +       P  +
Sbjct: 9554  HDIPEDAQLETAENSSVIIIPECKRSHTGKYSITAKNKAGQKTANCRVKVMDVPGPPKDL 9613

Query: 1456  DFSDITANSFTVHWIAPRAT----ITGYRIRHHPEHFSGRPREDRVPH-SRNSITLTNLT 1510
               SDIT  S  + W  P       I GY I        G+      P     +  + +L 
Sbjct: 9614  KVSDITRGSCRLSWKMPDDDGGDRIKGYVIEKRT--IDGKAWTKVNPDCGSTTFVVPDLL 9671

Query: 1511  PGTEYVVSIVALNGREESPLLIGQQSTVS-------DVPRDLEVVAATPTSLLISWDAPA 1563
                +Y   + A N     P +   Q T +       D P  L++   T  ++ +SW  P 
Sbjct: 9672  SEQQYFFRVRAENRFGIGPPVETIQRTTARDPIYPPDPPIKLKIGLITKNTVHLSWKPP- 9730

Query: 1564  VTVRYYRITYGETGGNSPVQEFTVP-------GSKSTA--------------TISGLKPG 1602
                        +  G SPV  + V        G+K  A              T+  L  G
Sbjct: 9731  -----------KNDGGSPVTHYIVECLAWDPTGTKKEAWRQCNKRDVEELQFTVEDLVEG 9779

Query: 1603  VDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTG 1662
              +Y   V AV   G S  S+             P   Q  D+   SI +K        T 
Sbjct: 9780  GEYEFRVKAVNAAGVSKPSATV----------GPCDCQRPDMPP-SIDLKEFMEVEEGTN 9828

Query: 1663  YRVTTTPKNGPGPT----KTKTAGPDQTEMTIEGLQPTVEYV----VSVYAQNPSGESQP 1714
               +    K  P PT    K     PD  E  +         V      V  Q+   ++  
Sbjct: 9829  VNIVAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDTGL 9888

Query: 1715  LVQTAVTNIDR---------------PKG-LAFTDVDVDSIKIAWESPQ----GQVSRYR 1754
                TAV N+                 P G + F  V  D + ++W  P+     +++ Y 
Sbjct: 9889  YTITAVNNLGTASKEMRLNVLGRPGPPVGPIKFESVSADQMTLSWFPPKDDGGSKITNYV 9948

Query: 1755  VTY--SSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVA-----LHDDMESQPLIG 1807
             +    ++ +  +H    + + +E T  +  L  G EY   ++A     + + ++S+P   
Sbjct: 9949  IEKREANRKTWVHV---SSEPKECTYTIPKLLEGHEYVFRIMAQNKYGIGEPLDSEPETA 10005

Query: 1808  TQSTAIP-APTDLKFTQVTPTSLSAQWTPPNVQ----LTGYRVRVTPKEKTGPM-KEINL 1861
                 ++P AP     + VT  S++  W  P       +TGY + +  K+ T    K +N 
Sbjct: 10006 RNLFSVPGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPVTGYWLEM--KDTTSKRWKRVNR 10063

Query: 1862  APDSS-----SVVVSGLMVATKYEVSVYALKD------TLTSRPAQGVVTTLENVSPPRR 1910
              P  +     S  V+GL+  + Y+  VYA+        +L S PA    T  + ++PP  
Sbjct: 10064 DPIKAMTLGVSYKVTGLIEGSDYQFRVYAINAAGVGPASLPSDPA----TARDPIAPPGP 10119

Query: 1911  A--RVTDATETTITISWRTKTET----ITGFQVDAVPANGQTPIQRTIKPDVRS--YTIT 1962
                +VTD T+++  + W    +     +TG+ V+     G+   ++    +VR     +T
Sbjct: 10120 PFPKVTDWTKSSADLEWSPPLKDGGSKVTGYIVE-YKEEGKEEWEKGKDKEVRGTKLVVT 10178

Query: 1963  GLQPGTDYKIYLYTLNDNARSSPV----VIDASTAIDAPSNLRFLATTPNSLLVSWQPPR 2018
             GL+ G  YK  +  +N      P     VI+    + +P +L+  A+  + ++V      
Sbjct: 10179 GLKEGAFYKFRVRAVNIAGIGEPGEVTDVIEMKDRLVSP-DLQLDASVRDRIVVH-AGGV 10236

Query: 2019  ARITGYIIKYEKPGSPPREVV--PRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPL 2076
              RI  Y+      G PP  V      R    EATI      T      + +KN Q+S   
Sbjct: 10237 IRIIAYV-----SGKPPPTVTWNMNERTLPQEATIE-----TTAISSSMVIKNCQRSHQG 10286

Query: 2077  I----------GRKKTV----------QKTPFVTHPGYDTGNGIQL----PGTSGQQPSV 2112
             +           RKKT+            TPF+ H    T    +L    P   G  P +
Sbjct: 10287 VYSLLAKNEAGERKKTIIVDVLDVPGPVGTPFLAHNL--TNESCKLTWFSPEDDGGSP-I 10343

Query: 2113  GQQMIFEEHGFRRTTPPTTATPIRHRPRPYPPNVGQ----EALSQTTISWAPFQDTSEYI 2168
                +I +    RR   P T T  R          G+       ++ +I   PF +TSE +
Sbjct: 10344 TNYVIEKRESDRRAWTPVTYTVTRQNATVQGLIQGKAYFFRIAAENSIGMGPFVETSEAL 10403

Query: 2169  ISCHPVGTDEEPLQFRVPG-TSTSATLT 2195
             +   P+   E P    V   T  + TLT
Sbjct: 10404 VIREPITVPERPEDLEVKEVTKNTVTLT 10431



 Score = 72.0 bits (175), Expect = 7e-12
 Identities = 342/1612 (21%), Positives = 545/1612 (33%), Gaps = 290/1612 (17%)

Query: 628   IQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISI 684
             + W +P+    S I+ Y++  R  +    W   T      + T++GL  G  Y  ++ + 
Sbjct: 10330 LTWFSPEDDGGSPITNYVIEKRESDRRA-WTPVTYTVTRQNATVQGLIQGKAYFFRIAAE 10388

Query: 685   QQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSAS 744
                G        F  TS +  +        T P  P       V E+T ++  ++W    
Sbjct: 10389 NSIGMGP-----FVETSEALVIREPI----TVPERP---EDLEVKEVTKNTVTLTWNPPK 10436

Query: 745   DTVSGFRVEYELSEE--GDEPQYLDLPSTATS--VNIPDLLPGRKYIVNVYQISEDGEQS 800
                    + Y L     G E  +        S    +  L  G  Y   V  ++  G+  
Sbjct: 10437 YDGGSEIINYVLESRLIGTEKFHKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGK 10496

Query: 801   LILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPE 860
                 T   T  D    PT+       + +R     A    Y     P V     E ++ E
Sbjct: 10497 PSFCTKPITCKDELAPPTLHLDFRDKLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLE 10556

Query: 861   TANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQET---TGTPRSDTVPSPRD----L 913
               +  T     P       I A   +     VV++  T    G  + + V  P      +
Sbjct: 10557 --DDRTHIKTTPATLALEKIKAKRSDSGKYCVVVENSTGSRKGFCQVNVVDRPGPPVGPV 10614

Query: 914   QFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPGEHGQRLPI---SRNTFAEVTG 966
              F EVT   + I W PP     S +T Y ++   V         +P+   S  T  +V+ 
Sbjct: 10615 SFDEVTKDYMVISWKPPLDDGGSKITNYIIEKKEVG----KDVWMPVTSASAKTTCKVSK 10670

Query: 967   LSPGVTYYFKVFAVSHGRESKPLTAQQTTKLD------APTNLQFVNETDSTVLVRWTPP 1020
             L  G  Y F++ A +    S PL +      D      AP        T  + LV W  P
Sbjct: 10671 LLEGKDYIFRIHAENLYGISDPLVSDSMKAKDRFRVPDAPDQPIVTEVTKDSALVTWNKP 10730

Query: 1021  R---AQITGYRLTVGLTRRGQPRQYNVGP--SVSKYPLRNLQPASEYTVSLVA---IKGN 1072
                   IT Y L    T   +  +    P    +K+ + +L    +Y   + A   I   
Sbjct: 10731 HDGGKPITNYILEKRETMSKRWARVTKDPIHPYTKFRVPDLLEGCQYEFRVSAENEIGIG 10790

Query: 1073  QESPKATGVFTTLQPGSSIPPYNTEVTETT---IVITWTPAPRIGFKLGVRPSQGGEAPR 1129
               SP +  VF         PP N E  +TT   + +TW P                  PR
Sbjct: 10791 DPSPPSKPVFAKDPIAKPSPPVNPEAIDTTCNSVDLTWQP------------------PR 10832

Query: 1130  EVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTG 1189
                 D GS ++        Y+   Q + D + R A              N   E+ P+T 
Sbjct: 10833 H---DGGSKILG-------YIVEYQKVGDEEWRRA--------------NHTPESCPETK 10868

Query: 1190  VLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPG---LEYNVS 1246
                       T     +R+      G+      +  H  +     D L P    L+ N++
Sbjct: 10869 YKVTGLRDGQTYK---FRVLAVNAAGES-----DPAHVPEPVLVKDRLEPPELILDANMA 10920

Query: 1247  VYTVKDDKESVPISDT-----IIPEVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGYRIT 1301
                    ++ + + DT     II  VP      F  +T       W   +       RI 
Sbjct: 10921 ------REQHIKVGDTLRLSAIIKGVP------FPKVT-------WKKEDRDAPTKARID 10961

Query: 1302  VVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAVPPP 1361
             V   G  + I  +      G Y++T   P     +SV  L+                 PP
Sbjct: 10962 VTPVGSKLEI-RNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDKPG------------PP 11008

Query: 1362  TDLRFTNIGPDTMRVTWAPPPSID---LTNFLVRYSPVKNEEDVAELSISPSDNAVVLTN 1418
              DL  + I  D+  +TW  P       +TN++V    V + +  + LS +    +    +
Sbjct: 11009 RDLEVSEIRKDSCYLTWKEPLDDGGSVITNYVVERRDVASAQ-WSPLSATSKKKSHFAKH 11067

Query: 1419  LLPGTEYVVSVSSVYEQHESTPLRGRQKT--GLDS------PTGIDFSDITANSFTVHWI 1470
             L  G +Y+  V++   Q+   P     K    LD       P  +   D+     ++ W 
Sbjct: 11068 LNEGNQYLFRVAAE-NQYGRGPFVETPKPIKALDPLHPPGPPKDLHHVDVDKTEVSLVWN 11126

Query: 1471  APR----ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN--- 1523
              P     + ITGY + +  E      +   V +      +T L  G  Y   + A N   
Sbjct: 11127 KPDRDGGSPITGYLVEYQEEGTQDWIKFKTVTNLE--CVVTGLQQGKTYRFRVKAENIVG 11184

Query: 1524  -GREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPV 1582
              G  ++ + I  Q  +  VP  +E+       L++       TVR+  I  G      P 
Sbjct: 11185 LGLPDTTIPIECQEKL--VPPSVELDVKLIEGLVVK---AGTTVRFPAIIRGVP---VPT 11236

Query: 1583  QEFTVPGSK---------------STATISGL--KPGVDYTITVYAVTGRGDSPASSKPI 1625
              ++T  GS+               S  TI     +   +Y ITV        + A SK +
Sbjct: 11237 AKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEYQITV-------SNAAGSKTV 11289

Query: 1626  SINYRTEIDKPSQ----MQVTDVQDNSISVKWLP----SSSPVTGYRVTT--TPKNGPGP 1675
             +++  T +D P      + + DV    +++ W P      SPV  Y V    T K+  G 
Sbjct: 11290 AVHL-TVLDVPGPPTGPINILDVTPEHMTISWQPPKDDGGSPVINYIVEKQDTRKDTWGV 11348

Query: 1676  TKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDR------PKGL 1729
                 ++G  +T++ I  LQ   EYV  V A+N  G   PL  T      +      P   
Sbjct: 11349 V---SSGSSKTKLKIPHLQKGCEYVFRVRAENKIGVGPPLDSTPTVAKHKFSPPSPPGKP 11405

Query: 1730  AFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQ----GLRP 1785
               TD+  ++  ++W  P+         Y      +   +   + +   A+L+    GL  
Sbjct: 11406 VVTDITENAATVSWTLPKSDGGSPITGYYMERREVTGKWVRVN-KTPIADLKFRVTGLYE 11464

Query: 1786  GSEYTVSVVALH------DDMESQPLIGTQSTAIPA-PTDLKFTQVTPTSLSAQWTPP-- 1836
             G+ Y   V A +          S P+   +    P  P + K    +  +    WT P  
Sbjct: 11465 GNTYEFRVFAENLAGLSKPSPSSDPIKACRPIKPPGPPINPKLKDKSRETADLVWTKPLS 11524

Query: 1837  --NVQLTGYRVRVTPKEKTGPMKEINLAP--DSSSVVVSGLMVATKYEVSVYALKDTLTS 1892
                  + GY V    K  T     IN        +  V GL+   +Y   + A       
Sbjct: 11525 DGGSPILGYVVE-CQKPGTAQWNRINKDELIRQCAFRVPGLIEGNEYRFRIKAANIVGEG 11583

Query: 1893  RP---AQGVVTTLENVSPPR-------RARVTDATETTITISWRTK-------TETITG- 1934
              P   A+ V+   + + PP        R  +T     TI I  R K       T T  G 
Sbjct: 11584 EPRELAESVIAK-DILHPPEVELDVTCRDVITVRVGQTIRILARVKGRPEPDITWTKEGK 11642

Query: 1935  -----FQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVID 1989
                   +VD +    +  +Q  IK  VR+           Y I     + +A+ S +V  
Sbjct: 11643 VLVREKRVDLIQDLPRVELQ--IKEAVRA-------DHGKYIISAKNSSGHAQGSAIV-- 11691

Query: 1990  ASTAIDAP---SNLRFLATTPNSLLVSWQPP----RARITGYIIKYEKPGSPPREVVPRP 2042
                 +D P    NL+    T  +  +SW+ P     + IT +I++Y KP      +V   
Sbjct: 11692 --NVLDRPGPCQNLKVTNVTKENCTISWENPLDNGGSEITNFIVEYRKPNQKGWSIV--- 11746

Query: 2043  RPGVTEATI-TGLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQKTPFVTHPG 2093
                VT+  I   L    EY   V A +N     P I  K  +     +  PG
Sbjct: 11747 ASDVTKRLIKANLLANNEYYFRVCA-ENKVGVGPTIETKTPILAINPIDRPG 11797



 Score = 64.3 bits (155), Expect = 1e-09
 Identities = 115/519 (22%), Positives = 183/519 (35%), Gaps = 81/519 (15%)

Query: 1633  IDKPS---QMQVTDVQDNSISVKWLPSSSP----VTGYRVTTTP-KNGPGPTKTKTAGPD 1684
             +DKP     +++ DV  +  +V W P        +  Y +     K     T + T    
Sbjct: 11989 LDKPGPVRNLKIVDVSSDRCTVCWDPPEDDGGCEIQNYILEKCETKRMVWSTYSATVLTP 12048

Query: 1685  QTEMT--IEGLQPTVEYVVSVYAQN-----PSGESQPLV-QTAVTNIDRPKGLAFTDVDV 1736
              T +T  IEG     EY+  V A+N     P  ES+P++ +T      RP     T V  
Sbjct: 12049 GTTVTRLIEGN----EYIFRVRAENKIGTGPPTESKPVIAKTKYDKPGRPDPPEVTKVSK 12104

Query: 1737  DSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGE----EDTAELQGLRPGSEYTVS 1792
             + + + W  P+    +    Y   +   H     P  +    E   ++Q L P  EY   
Sbjct: 12105 EEMTVVWNPPEYDGGKSITGYFLEKKEKHSTRWVPVNKSAIPERRMKVQNLLPDHEYQFR 12164

Query: 1793  VVALHD------DMESQPLIGTQSTAIPAP-TDLKFTQVTPTSLSAQWTPP----NVQLT 1841
             V A ++       + S+P++       P P T+ +    T  S++  W  P       + 
Sbjct: 12165 VKAENEIGIGEPSLPSRPVVAKDPIEPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAPII 12224

Query: 1842  GYRVRVTPKEKTGP----MKEINLAPD--SSSVVVSGLMVATKYEVSVYALKDTLTSRPA 1895
             GY V + PK          K  N A         V+ L    +YE  V A       RPA
Sbjct: 12225 GYVVEMRPKIADASPDEGWKRCNAAAQLVRKEFTVTSLDENQEYEFRVCAQNQVGIGRPA 12284

Query: 1896  Q--GVVTTLENVSPPRRARVTDATETTIT-------------------ISWRTK--TETI 1932
             +    +   E + PP         +  I                    ++WR       +
Sbjct: 12285 ELKEAIKPKEILEPPEIDLDASMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVV 12344

Query: 1933  TGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDAST 1992
                QVD V       I  + + D   Y++T + P  +  +++     N R    V+D   
Sbjct: 12345 RKGQVDLVDTMAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFV-----NVR----VLDTPG 12395

Query: 1993  AIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREVVPRPRPGVTE 2048
              +   S+L+    T  S  VSW PP     +++T YI++  +        V  P    T 
Sbjct: 12396 PV---SDLKVSDVTKTSCHVSWAPPENDGGSQVTHYIVEKREADRKTWSTVT-PEVKKTS 12451

Query: 2049  ATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQKTP 2087
               +T L PG EY   V A+       P    K  +   P
Sbjct: 12452 FHVTNLVPGNEYYFRVTAVNEYGPGVPTDVPKPVLASDP 12490



 Score = 61.6 bits (148), Expect = 9e-09
 Identities = 181/841 (21%), Positives = 296/841 (35%), Gaps = 156/841 (18%)

Query: 1360 PPTDLRFTNIGPDTMRVTWAPPPS---IDLTNFLVRYSPVKNEEDVAELSISPSDNAVVL 1416
            P  +L  T      + + W  P +     +  ++V    +K +  V     + S    V 
Sbjct: 6787 PVRNLEVTETFDGEVSLAWEEPLTDGGSKIIGYVVERRDIKRKTWVLATDRAESCEFTVT 6846

Query: 1417 TNLLPGTEYVVSVSS-----VYEQHES-TPLRGRQKTGLDSPT-GIDFSDITANSFTVHW 1469
                 G EY+  VS+       E  E+  P+  R K  +  P   +  +D+     ++ W
Sbjct: 6847 GLQKGGVEYLFRVSARNRVGTGEPVETDNPVEARSKYDVPGPPLNVTITDVNRFGVSLTW 6906

Query: 1470 IAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGR 1525
              P     A IT Y I    +          V     S T+T++  G EY   +     R
Sbjct: 6907 EPPEYDGGAEITNYVIELRDKTSIRWDTAMTVRAEDLSATVTDVVEGQEYSFRV-----R 6961

Query: 1526 EESPLLIGQQSTVSDV------------PRDLEVVAATPTSLLISWDAP----AVTVRYY 1569
             ++ + +G+ S  +              P +L     T +S+ + W+ P       +  Y
Sbjct: 6962 AQNRIGVGKPSAATPFVKVADPIERPSPPVNLTSSDQTQSSVQLKWEPPLKDGGSPILGY 7021

Query: 1570 RITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINY 1629
             I   E G ++ ++       + T  ++GL+ G  Y   V A    G S  S     +  
Sbjct: 7022 IIERCEEGKDNWIRCNMKLVPELTYKVTGLEKGNKYLYRVSAENKAGVSDPSEILGPLTA 7081

Query: 1630 RTEIDKPSQMQVTDVQDNSISVKWLPSSS--PVTGYRVTTTPKNGPGPTKTKTAGPDQTE 1687
                 +P+ M ++  +D    +   P +   P TGY         P PT T   G    E
Sbjct: 7082 DDAFVEPT-MDLSAFKDGLEVIVPNPITILVPSTGY---------PRPTATWCFGDKVLE 7131

Query: 1688 ----MTIEGLQPTVEYVVSVYAQNPSG----ESQPLVQTAVTNID--------RPKGLAF 1731
                + ++ L    E V+S   ++  G    + +  V+T    ID         PK L F
Sbjct: 7132 TGDRVKMKTLSAYAELVISPSERSDKGIYTLKLENRVKTISGEIDVNVIARPSAPKELKF 7191

Query: 1732 TDVDVDSIKIAWESPQ----GQVSRY--------RVTYSSPEDGIHEL-FPAPDGEEDTA 1778
             D+  DS+ + WE P       ++ Y        R T++   D + +L F  PD      
Sbjct: 7192 GDITKDSVHLTWEPPDDDGGSPLTGYVVEKREVSRKTWTKVMDFVTDLEFTVPD------ 7245

Query: 1779 ELQGLRPGSEYTVSVVALHDDMESQPL-------IGTQSTAIPAPTDLKFTQVTPTSLSA 1831
                L  G EY   V A +     +P        + T +T    P ++K+   T  S+  
Sbjct: 7246 ----LVQGKEYLFKVCARNKCGPGEPAYVDEPVNMSTPATVPDPPENVKWRDRTANSIFL 7301

Query: 1832 QWTPP----NVQLTGYRVRVTPKEKTGPMKEINLAPD--SSSVVVSGLMVATKYEVSVYA 1885
             W PP      ++ GY V   P+   G  K +        + + V+GL     Y   V A
Sbjct: 7302 TWDPPKNDGGSRIKGYIVERCPR---GSDKWVACGEPVAETKMEVTGLEEGKWYAYRVKA 7358

Query: 1886 LKDTLTSRPAQGVVTTLENVSPPRRARVTDATETT-----------ITISWRTKTE---T 1931
            L     S+P++          P    +  D  E             +T+   TK E   T
Sbjct: 7359 LNRQGASKPSR----------PTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPAT 7408

Query: 1932 ITGFQVDAVPANGQTPIQRTIKPDVR----------SYTITGLQPGTDYKIYLYTLNDNA 1981
            +TG      P    T     +K D R          + TI   +        +  +N   
Sbjct: 7409 VTG---KPEPKITWTKADMILKQDKRITIENVPKKSTVTIVDSKRSDTGTYIIEAVNVCG 7465

Query: 1982 RSSPVV-IDASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPR 2036
            R++ VV ++       P+       T  S L++W PPR    ++IT Y+++     S   
Sbjct: 7466 RATAVVEVNVLDKPGPPAAFDITDVTNESCLLTWNPPRDDGGSKITNYVVERRATDS--- 7522

Query: 2037 EVVPRPRPGV--TEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQKTPFVTHPGY 2094
            EV  +    V  T    T L P  EY   V A       E + G  + VQ +P      +
Sbjct: 7523 EVWHKLSSTVKDTNFKATKLIPNKEYIFRVAA-------ENMYGVGEPVQASPITAKYQF 7575

Query: 2095 D 2095
            D
Sbjct: 7576 D 7576



 Score = 58.2 bits (139), Expect = 1e-07
 Identities = 314/1663 (18%), Positives = 573/1663 (34%), Gaps = 254/1663 (15%)

Query: 611   PVEVFITETPSQP-----------NSHPIQWNAPQPS---HISKYILRWRPKNSVGRWKE 656
             P+ V     PS+P           +S  + W+ P+ +    I+ Y +  R + S   WK 
Sbjct: 21343 PITVITLGPPSKPKGPIRFDEIKADSVILSWDVPEDNGGGEITCYSIEKR-ETSQTNWKM 21401

Query: 657   ATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETT 716
                     ++ +  L     Y+ ++ +  +YG              S P+ S+ +  +  
Sbjct: 21402 VCSSVARTTFKVPNLVKDAEYQFRVRAENRYG-------------VSQPLVSSIIVAKHQ 21448

Query: 717   PFSPLVATSESVTEITASSFVVSW----VSASDTVSGFRVEYELSEEGDEPQYLDLPSTA 772
                P       +  +T+    ++W          V+GF VE +        +    P + 
Sbjct: 21449 FRIPGPPGKPVIYNVTSDGMSLTWDAPVYDGGSEVTGFHVEKKERNSILWQKVNTSPISG 21508

Query: 773   TSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDP--TVDQVDDT--SIV 828
                    L+ G  Y   VY  +  G  S     S+ T   +P DP  T D +D T  +I 
Sbjct: 21509 REYRATGLVEGLDYQFRVYAENSAGLSSPS-DPSKFTLAVSPVDPPGTPDYIDVTRETIT 21567

Query: 829   VRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETAN-SVTLSDLQPGVQYNITIYA- 882
             ++W+ P     + I GY I      E      N  + +    T++ L PG +Y   I A 
Sbjct: 21568 LKWNPPLRDGGSKIVGYSIEKRQGNE-RWVRCNFTDVSECQYTVTGLSPGDRYEFRIIAR 21626

Query: 883   -----VEENQESTPVVIQQETTGTPRSDTVPSPRD---LQFVEVTDVKVTIMWTPPESAV 934
                  +    +S+ +++ ++    P  +  P   D   ++  E   +K  +   P    V
Sbjct: 21627 NAVGTISPPSQSSGIIMTRDENVPPIVEFGPEYFDGLIIKSGESLRIKALVQGRPVPR-V 21685

Query: 935   TGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFK--------VFAVSHGRES 986
             T ++  V              I +    E+T +    + + +        V+ V     S
Sbjct: 21686 TWFKDGV-------------EIEKRMNMEITDVLGSTSLFVRDATRDHRGVYTVEAKNAS 21732

Query: 987   KPLTAQQTTKL-DAPTN----LQFVNETDSTVLVRWTPPR----AQITGYRLTVGLTRRG 1037
                 A+   K+ D P      ++F N T   + + W  P     A IT Y +    T R 
Sbjct: 21733 GSAKAEIKVKVQDTPGKVVGPIRFTNITGEKMTLWWDAPLNDGCAPITHYIIEKRETSRL 21792

Query: 1038  QPRQYNVGPSVSKYPLRNLQPASEYTVSLVAI------KGNQESPKATGVFTTLQPGSSI 1091
                          Y    L   +EY   + A+      +     P    +  T+     I
Sbjct: 21793 AWALIEDKCEAQSYTAIKLINGNEYQFRVSAVNKFGVGRPLDSDPVVAQIQYTVPDAPGI 21852

Query: 1092  PPYNTEVTETTIVITWTPAPRIG------FKLGVRPSQGGEAPREVTSDSGS---IVVSG 1142
             P   + +T  +I +TW      G      + L  R  +     + ++    S     V+G
Sbjct: 21853 PE-PSNITGNSITLTWARPESDGGSEIQQYILERREKKSTRWVKVISKRPISETRFKVTG 21911

Query: 1143  LTPGVEYVYTIQVLRDGQERDAPIVNKVVT---PLSPPTNLHLEANPDTGVLTVSWERST 1199
             LT G EY + +          A  +++++    P++PP    +    DT   TVS E S 
Sbjct: 21912 LTEGNEYEFHVMAENAAGVGPASGISRLIKCREPVNPPGPPTVVKVTDTSKTTVSLEWSK 21971

Query: 1200  TP-----DITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKD-- 1252
                    +I GY I     +    + +       ++  T  +L  G EY   V  +    
Sbjct: 21972 PVFDGGMEIIGYIIEMCKADLGDWHKVNAEACV-KTRYTVTDLQAGEEYKFRVSAINGAG 22030

Query: 1253  DKESVPISDTI-------IPEVPQLTDLSFVDITDSSIGLR--------------WTPLN 1291
               +S  ++ TI        PE+    +     +  +   +R              W+  +
Sbjct: 22031 KGDSCEVTGTIKAVDRLTAPELDIDANFKQTHVVRAGASIRLFIAYQGRPTPTAVWSKPD 22090

Query: 1292  SSTIIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTT 1351
             S+  +   I    +   + + E+   +  G YT+T            +   +G +S   T
Sbjct: 22091 SNLSLRADIHTTDSFSTLTV-ENCNRNDAGKYTLT------------VENNSGSKSITFT 22137

Query: 1352  LTQQTAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAE---LSIS 1408
             +       PP  + F ++   +  + W   P +D    +  Y   K E        +S  
Sbjct: 22138 VKVLDTPGPPGPITFKDVTRGSATLMW-DAPLLDGGARIHHYVVEKREASRRSWQVISEK 22196

Query: 1409  PSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDS----PTGIDFSDITANS 1464
              +     + +L  G  Y   VS+V E     P    +          P  +D  D + +S
Sbjct: 22197 CTRQIFKVNDLAEGVPYYFRVSAVNEYGVGEPYEMPEPIVATEQPAPPRRLDVVDTSKSS 22256

Query: 1465  FTVHWIAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRN-SITLTNLTPGTEYVVSI 1519
               + W+ P     + ITGY +    +   G        H++  + T+  L   TEY   +
Sbjct: 22257 AVLAWLKPDHDGGSRITGYLLEMRQK---GSDFWVEAGHTKQLTFTVERLVEKTEYEFRV 22313

Query: 1520  VALNGREESPLLIGQQSTVSDVPR-----DLEVV--------AATPTSL---LISWDAPA 1563
              A N    S       S +   P+     DL  +        A +P ++   +    AP 
Sbjct: 22314 KAKNDAGYSEPREAFSSVIIKEPQIEPTADLTGITNQLITCKAGSPFTIDVPISGRPAPK 22373

Query: 1564  VTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVD--YTITVYAVTGRGDSPAS 1621
             VT +   +   ET   S     T    ++T T+     G    Y +T+       ++ A 
Sbjct: 22374 VTWKLEEMRLKETDRVS----ITTTKDRTTLTVKDSMRGDSGRYFLTL-------ENTAG 22422

Query: 1622  SKPISINYRTEIDKPSQM----QVTDVQDNSISVKWLP----SSSPVTGYRVTTTPKNGP 1673
              K  S+     I +P  +    +V+ V   S  + W        + +T Y +    ++G 
Sbjct: 22423 VKTFSVTV-VVIGRPGPVTGPIEVSSVSAESCVLSWGEPKDGGGTEITNY-IVEKRESGT 22480

Query: 1674  GPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAV------TNIDRPK 1727
                +   +   +T++ +  L   +EY   V ++N  G S+PL    +           P 
Sbjct: 22481 TAWQLVNSSVKRTQIKVTHLTKYMEYSFRVSSENRFGVSKPLESAPIIAEHPFVPPSAPT 22540

Query: 1728  GLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGE----EDTAELQGL 1783
                   V  +++ I WE P        + Y   +   + +    + +    E   ++ GL
Sbjct: 22541 RPEVYHVSANAMSIRWEEPYHDGGSKIIGYWVEKKERNTILWVKENKVPCLECNYKVTGL 22600

Query: 1784  RPGSEYTVSVVALH------DDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPP- 1836
               G EY     AL+          S+P++      + AP   + T VT +++S  W+ P 
Sbjct: 22601 VEGLEYQFRTYALNAAGVSKASEASRPIMA--QNPVDAPGRPEVTDVTRSTVSLIWSAPA 22658

Query: 1837  ---NVQLTGYRVRVTPKEKTGP---MKEINLAPDSSSVVVSGLMVATKYEVSVYALKDT- 1889
                  ++ GY +   P  + G    +K        +   V+ L     YE  V A     
Sbjct: 22659 YDGGSKVVGYIIERKPVSEVGDGRWLKCNYTIVSDNFFTVTALSEGDTYEFRVLAKNAAG 22718

Query: 1890  LTSRPAQ--GVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVP------ 1941
             + S+ ++  G VT  +  +PP+     DA      ++ R  ++ +    V   P      
Sbjct: 22719 VISKGSESTGPVTCRDEYAPPKAE--LDARLHGDLVTIRAGSDLVLDAAVGGKPEPKIIW 22776

Query: 1942  ANGQTPIQRTIKPDV-----RSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDA 1996
               G   +    K  +     R+  +      +D   Y  T+  NA  +  V      +D+
Sbjct: 22777 TKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSGKYTLTVK-NASGTKAVSVMVKVLDS 22835

Query: 1997  P---SNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREVVPRPRPGVTEA 2049
             P     L     T     ++W  P+    A IT YI++  +       +V    P ++  
Sbjct: 22836 PGPCGKLTVSRVTQEKCTLAWSLPQEDGGAEITHYIVERRETSRLNWVIVEGECPTLS-Y 22894

Query: 2050  TITGLEPGTEYTIYVIALKN-----NQKSEPLIGRKKTVQKTP 2087
              +T L    EY   V A+         +SEP++ R      +P
Sbjct: 22895 VVTRLIKNNEYIFRVRAVNKYGPGVPVESEPIVARNSFTIPSP 22937



 Score = 55.5 bits (132), Expect = 6e-07
 Identities = 128/535 (23%), Positives = 202/535 (37%), Gaps = 90/535 (16%)

Query: 593   GIGEWHCQPLQTYPSSSGPVEVFITETPSQP-------NSHPIQWNAPQ---PSHISKYI 642
             GIGE    PL + P ++  +   +   P +P       NS  + W  P+    S ++ Y 
Sbjct: 9993  GIGE----PLDSEPETARNL-FSVPGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPVTGYW 10047

Query: 643   LRWRPKNSVGRWK-------EATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRF 695
             L  +   S  RWK       +A   G   SY + GL  G  Y+ ++ +I   G    +  
Sbjct: 10048 LEMKDTTSK-RWKRVNRDPIKAMTLGV--SYKVTGLIEGSDYQFRVYAINAAGVGPASL- 10103

Query: 696   DFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWV----SASDTVSGFR 751
                    S P T+        P +P       VT+ T SS  + W          V+G+ 
Sbjct: 10104 ------PSDPATARD------PIAPPGPPFPKVTDWTKSSADLEWSPPLKDGGSKVTGYI 10151

Query: 752   VEYELSEEGDEP--QYLDLPSTATSVNIPDLLPGRKY-----IVNVYQISEDGEQSLILS 804
             VEY+  EEG E   +  D     T + +  L  G  Y      VN+  I E GE + ++ 
Sbjct: 10152 VEYK--EEGKEEWEKGKDKEVRGTKLVVTGLKEGAFYKFRVRAVNIAGIGEPGEVTDVIE 10209

Query: 805   TSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETA-- 862
                       PD  +D      IVV        I        P+V  +  E  LP+ A  
Sbjct: 10210 MKDRLVS---PDLQLDASVRDRIVVHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEATI 10266

Query: 863   ------NSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFV 916
                   +S+ + + Q   Q   ++ A  E  E    +I            VP P    F+
Sbjct: 10267 ETTAISSSMVIKNCQRSHQGVYSLLAKNEAGERKKTIIVDVLD-------VPGPVGTPFL 10319

Query: 917   --EVTDVKVTIMWTPPE----SAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPG 970
                +T+    + W  PE    S +T Y ++    +          ++R   A V GL  G
Sbjct: 10320 AHNLTNESCKLTWFSPEDDGGSPITNYVIEKRESDRRAWTPVTYTVTRQN-ATVQGLIQG 10378

Query: 971   VTYYFKVFA---VSHG---RESKPLTAQQT-TKLDAPTNLQFVNETDSTVLVRWTPPR-- 1021
               Y+F++ A   +  G     S+ L  ++  T  + P +L+    T +TV + W PP+  
Sbjct: 10379 KAYFFRIAAENSIGMGPFVETSEALVIREPITVPERPEDLEVKEVTKNTVTLTWNPPKYD 10438

Query: 1022  --AQITGYRLTVGLTRRGQPRQYNVGPSVS-KYPLRNLQPAS--EYTVSLVAIKG 1071
               ++I  Y L   L    +  +      +S KY ++ L+     EY VS V I G
Sbjct: 10439 GGSEIINYVLESRLIGTEKFHKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVG 10493



 Score = 52.8 bits (125), Expect = 4e-06
 Identities = 80/336 (23%), Positives = 120/336 (35%), Gaps = 46/336 (13%)

Query: 602  LQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQP---SHISKYILRWRPKN-SVGRWKEA 657
            ++ Y   S P  + +T+  ++  S  + W+AP     S I+ Y++  R  +     W+E 
Sbjct: 9187 VEVYDRPSPPRNLAVTDIKAE--SCYLTWDAPLDNGGSEITHYVIDKRDASRKKAEWEEV 9244

Query: 658  TIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTP 717
            T       Y I  L P   YE ++ ++ +YG  +  + D         V  +       P
Sbjct: 9245 TNTAVEKRYGIWKLIPNGQYEFRVRAVNKYGISDECKSD-------KVVIQDPYRLPGPP 9297

Query: 718  FSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTA----- 772
              P V         T  S +VSW    D        Y L +  +   Y    S A     
Sbjct: 9298 GKPKVLAR------TKGSMLVSWTPPLDNGGSPITGYWLEKREEGSPYWSRVSRAPITKV 9351

Query: 773  ----TSVNIPDLLPGRKY-----IVNVYQISEDGEQSLILSTSQTTAPDAPPD-PTVDQV 822
                   N+P LL G KY      +N   I    E S          P  PP  P V   
Sbjct: 9352 GLKGVEFNVPRLLEGVKYQFRAMAINAAGIGPPSEPSDPEVAGDPIFPPGPPSCPEVKDK 9411

Query: 823  DDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPE---TANSVTLSDLQPGVQ 875
              +SI + W  P     +PI GY +            +N P+   T     + +L+   +
Sbjct: 9412 TKSSISLGWKPPAKDGGSPIKGYIVEMQEEGTTDWKRVNEPDKLITTCECVVPNLKELRK 9471

Query: 876  YNITIYAVEENQESTPVVIQQETTG-TPRSDTVPSP 910
            Y   + AV E  ES P     +TTG  P +D    P
Sbjct: 9472 YRFRVKAVNEAGESEP----SDTTGEIPATDIQEEP 9503



 Score = 48.5 bits (114), Expect = 8e-05
 Identities = 107/537 (19%), Positives = 187/537 (34%), Gaps = 65/537 (12%)

Query: 610   GPVEVFITETPSQPNSHPIQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSY 666
             GPV        ++ + H + W  P+    S ++ YI+  R  +    W   T      S+
Sbjct: 12395 GPVSDLKVSDVTKTSCH-VSWAPPENDGGSQVTHYIVEKREADRK-TWSTVTPEVKKTSF 12452

Query: 667   TIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSE 726
              +  L PG  Y  ++ ++ +YG           T    PV ++    E  P   L     
Sbjct: 12453 HVTNLVPGNEYYFRVTAVNEYG-------PGVPTDVPKPVLASDPLSEPDPPRKL----- 12500

Query: 727   SVTEITASSFVVSWV----SASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLP 782
              VTE+T +S  ++W+         + G+   Y   E+  +           S+ +  L  
Sbjct: 12501 EVTEMTKNSATLAWLPPLRDGGAKIDGYITSYREEEQPADRWTEYSVVKDLSLVVTGLKE 12560

Query: 783   GRKY-----IVNVYQISEDGEQSLILSTSQTTAPD---APPDPTVDQVDDTSIVVRWSRP 834
             G+KY       N   +S   E   +    +   P     P   T+       I       
Sbjct: 12561 GKKYKFRVAARNAVGVSLPREAEGVYEAKEQLLPPKILMPEQITIKAGKKLRIEAHVYGK 12620

Query: 835   QAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDL--QPGVQYNITIYAVEENQESTPV 892
               P   ++      V  S   ++  ++++ + + D+  +    Y++T             
Sbjct: 12621 PHPTCKWKKGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIK 12680

Query: 893   VIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPG 948
             V+  +  G P+      P D+  ++      ++ W  P     S +T Y V+   V+  G
Sbjct: 12681 VVVMDAPGPPQ-----PPFDISDIDAD--ACSLSWHIPLEDGGSNITNYIVEKCDVS-RG 12732

Query: 949   EHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKL------DAPTN 1002
             +    L     T   V  L PG  Y F+V A +    S+PLT+ +            P N
Sbjct: 12733 DWVTALASVTKTSCRVGKLIPGQEYIFRVRAENRFGISEPLTSPKMVAQFPFGVPSEPKN 12792

Query: 1003  LQFVNETDSTVLVRWTPPRAQ----ITGYRLTVGLTRRGQPRQYNVGPSV---SKYPLRN 1055
              +        + V W  P +     I GY   +    R          ++   ++YP   
Sbjct: 12793 ARVTKVNKDCIFVAWDRPDSDGGSPIIGY--LIERKERNSLLWVKANDTLVRSTEYPCAG 12850

Query: 1056  LQPASEYTVSLVAIKGNQESP--KATGVFTTLQPGSSIPPYNTE---VTETTIVITW 1107
             L    EY+  + A+     SP  K T   T   P    PP   E   VT++T+ + W
Sbjct: 12851 LVEGLEYSFRIYALNKAGSSPPSKPTEYVTARMPVD--PPGKPEVIDVTKSTVSLIW 12905



 Score = 43.9 bits (102), Expect = 0.002
 Identities = 50/204 (24%), Positives = 83/204 (40%), Gaps = 22/204 (10%)

Query: 717   PFSPLVATSESVTEITASSFVVSWVSASDT----VSGFRVEYELSEEGDEPQYLDLPSTA 772
             P  P+V     +  +  +S V+SW   +D     ++ + VE   ++EG E Q +    + 
Sbjct: 24421 PTGPIV-----IEALLKNSAVISWKPPADDGGSWITNYVVEKCEAKEGAEWQLVSSAISV 24475

Query: 773   TSVNIPDLLPGRKYIV-----NVYQISEDGE-QSLILSTSQTTAPDAPPDPTVDQVDDTS 826
             T+  I +L     Y       N + IS+  E  S+++  S    P AP  PT+  V   S
Sbjct: 24476 TTCRIVNLTENAGYYFRVSAQNTFGISDPLEVSSVVIIKSPFEKPGAPGKPTITAVTKDS 24535

Query: 827   IVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSV-TLSDLQPGVQYNITIY 881
              VV W  P     A I  Y +      +     +   E   +V ++ +L  G++Y   + 
Sbjct: 24536 CVVAWKPPASDGGAKIRNYYLEKREKKQNKWISVTTEEIRETVFSVKNLIEGLEYEFRVK 24595

Query: 882   AVEENQESTPVVIQQETTGTPRSD 905
                   ES    I +    TP+SD
Sbjct: 24596 CENLGGESEWSEISEPI--TPKSD 24617



 Score = 41.2 bits (95), Expect = 0.013
 Identities = 92/413 (22%), Positives = 157/413 (38%), Gaps = 51/413 (12%)

Query: 1376  VTWAPPPSID---LTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSV 1432
             ++W PP       +TN++V     K   +   +S + S     + NL     Y   VS+ 
Sbjct: 24437 ISWKPPADDGGSWITNYVVEKCEAKEGAEWQLVSSAISVTTCRIVNLTENAGYYFRVSAQ 24496

Query: 1433  YEQHESTPLRGRQKTGLDSPTGID-------FSDITANSFTVHWIAPRATITGYRIRHHP 1485
                  S PL       + SP            + +T +S  V W  P A+  G +IR++ 
Sbjct: 24497 NTFGISDPLEVSSVVIIKSPFEKPGAPGKPTITAVTKDSCVVAW-KPPASDGGAKIRNYY 24555

Query: 1486  EHFSGRPREDRVPHSRNSITLT-----NLTPGTEYVVSIVA--LNGREESPLLIGQQSTV 1538
                  + +   +  +   I  T     NL  G EY   +    L G  E   +    +  
Sbjct: 24556 LEKREKKQNKWISVTTEEIRETVFSVKNLIEGLEYEFRVKCENLGGESEWSEISEPITPK 24615

Query: 1539  SDVP----------RDLEVVAATPTSLLISWDA-PAVTVRYYRITYGET----GGNSPVQ 1583
             SDVP          R+L V   +  +L+      P   V++YR   G+     G    +Q
Sbjct: 24616 SDVPIQAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYR--QGKEIIADGLKYRIQ 24673

Query: 1584  EFTVPGSKSTATISGLKPGVDYTITVYAV--TGRGDSPASSKPISINYRTEIDKPSQMQ- 1640
             EF   G      I+ +    D   TVY V  T +G S + +  + +    +I  P  ++ 
Sbjct: 24674 EFK--GGYHQLIIASV---TDDDATVYQVRATNQGGSVSGTASLEVEVPAKIHLPKTLEG 24728

Query: 1641  ---VTDVQDNSISVKWLPSSS---PVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQ 1694
                V  ++   +S+K +P S    PV  ++      +  G  +        + +   G++
Sbjct: 24729 MGAVHALRGEVVSIK-IPFSGKPDPVITWQKGQDLIDNNGHYQVIVTRSFTSLVFPNGVE 24787

Query: 1695  PTVEYVVSVYAQNPSGESQPLVQTAVTNI-DRPKGLAFTDVDVDSIKIAWESP 1746
                     V A+N  G  Q  V+  V ++ D P+G+  +DV  DS+ + W  P
Sbjct: 24788 RKDAGFYVVCAKNRFGIDQKTVELDVADVPDPPRGVKVSDVSRDSVNLTWTEP 24840



 Score = 37.7 bits (86), Expect = 0.14
 Identities = 36/131 (27%), Positives = 53/131 (40%), Gaps = 8/131 (6%)

Query: 894   IQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPVNLPGE 949
             I Q+T     +D    PR ++  +V+   V + WT P     S +T Y V+        E
Sbjct: 24804 IDQKTVELDVADVPDPPRGVKVSDVSRDSVNLTWTEPASDGGSKITNYIVEKCATT--AE 24861

Query: 950   HGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQ--TTKLDAPTNLQFVN 1007
                R+  +R T   V  L    +Y F+V A +    SKP    +   TK D    + +  
Sbjct: 24862 RWLRVGQARETRYTVINLFGKTSYQFRVIAENKFGLSKPSEPSEPTITKEDKTRAMNYDE 24921

Query: 1008  ETDSTVLVRWT 1018
             E D T  V  T
Sbjct: 24922 EVDETREVSMT 24932



 Score = 35.0 bits (79), Expect = 0.90
 Identities = 38/169 (22%), Positives = 71/169 (42%), Gaps = 17/169 (10%)

Query: 1610  YAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWL-PSS---SPVTGYRV 1665
             Y V  +       K + ++     D P  ++V+DV  +S+++ W  P+S   S +T Y V
Sbjct: 24794 YVVCAKNRFGIDQKTVELDVADVPDPPRGVKVSDVSRDSVNLTWTEPASDGGSKITNYIV 24853

Query: 1666  TTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPL--VQTAVTNI 1723
                        +   A   +T  T+  L     Y   V A+N  G S+P    +  +T  
Sbjct: 24854 EKCATTAERWLRVGQA--RETRYTVINLFGKTSYQFRVIAENKFGLSKPSEPSEPTITKE 24911

Query: 1724  DRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPD 1772
             D+ + + + D +VD  +        +VS  + ++SS ++   +   A D
Sbjct: 24912 DKTRAMNY-DEEVDETR--------EVSMTKASHSSTKELYEKYMIAED 24951


>gi|110349713 titin isoform novex-1 [Homo sapiens]
          Length = 27051

 Score =  175 bits (444), Expect = 4e-43
 Identities = 382/1656 (23%), Positives = 623/1656 (37%), Gaps = 244/1656 (14%)

Query: 630   WNAPQPSHISK---YILRWRPKNSVG--RWKEA--TIPGHLNSYTIKGLKPGVVYEGQLI 682
             W+AP     SK   YI+  +P + VG  RW +   TI    N +T+  L  G  YE +++
Sbjct: 22587 WSAPAYDGGSKVVGYIIERKPVSEVGDGRWLKCNYTIVSD-NFFTVTALSEGDTYEFRVL 22645

Query: 683   SIQQYGHQEVTRFDFTTTSTST-PVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWV 741
             +    G         +  S ST PVT                  + VT    S  V+   
Sbjct: 22646 AKNAAGV-------ISKGSESTGPVTCRDEYAPPKAELDARLHGDLVTIRAGSDLVL--- 22695

Query: 742   SASDTVSGFRVEYELS-EEGDEP---------QYLDLPSTATSVNIPDLLPGRKYIVNVY 791
                D   G + E ++   +GD+          QY    +TA  +   D     KY + V 
Sbjct: 22696 ---DAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAV-IKFCDRSDSGKYTLTVK 22751

Query: 792   QISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ----APITGYRIVYSP 847
               S  G +++ +      +P      TV +V      + WS PQ    A IT Y +    
Sbjct: 22752 NAS--GTKAVSVMVKVLDSPGPCGKLTVSRVTQEKCTLAWSLPQEDGGAEITHYIVERRE 22809

Query: 848   S-------VEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG 900
             +       VEG    L       S  ++ L    +Y   + AV +     PV  + E   
Sbjct: 22810 TSRLNWVIVEGECPTL-------SYVVTRLIKNNEYIFRVRAVNKYGPGVPV--ESEPIV 22860

Query: 901   TPRSDTVPSPRDL-QFVEVTDVKVTIMWTPPES----AVTGYRVDVIPV-NLPGEHGQRL 954
                S T+PSP  + + V      + I WT PES     ++ Y VD     +L      + 
Sbjct: 22861 ARNSFTIPSPPGIPEEVGTGKEHIIIQWTKPESDGGNEISNYLVDKREKKSLRWTRVNKD 22920

Query: 955   PISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNL-------QFVN 1007
              +  +T  +VT L  G  Y F+V AV+    S+P  A        P+         + V+
Sbjct: 22921 YVVYDTRLKVTSLMEGCDYQFRVTAVNAAGNSEPSEASNFISCREPSYTPGPPSAPRVVD 22980

Query: 1008  ETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSV--SKYPLRNLQPASE 1061
              T  ++ + WT P       I GY L +      Q  + +   ++  +++ + +L+   +
Sbjct: 22981 TTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDTDQWYRVHTNATIRNTEFTVPDLKMGQK 23040

Query: 1062  YT--VSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGV 1119
             Y+  V+ V +KG  E  ++      ++P   I   + E+ +    +  T   R G  L +
Sbjct: 23041 YSFRVAAVNVKGMSEYSES---IAEIEPVERIEIPDLELADD---LKKTVTIRAGASLRL 23094

Query: 1120  RPSQGGEAPREVT-----SDSGSIVVSGLTPGVEYV------------YTIQVLRDGQER 1162
               S  G  P  +T      D  S  +   T     +            YTI+      ++
Sbjct: 23095 MVSVSGRPPPVITWSKQGIDLASRAIIDTTESYSLLIVDKVNRYDAGKYTIEAENQSGKK 23154

Query: 1163  DAPIVNKVV-TPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSL 1221
              A ++ KV  TP   P+    E + D+  +T++WE    P I G      P N       
Sbjct: 23155 SATVLVKVYDTPGPCPSVKVKEVSRDS--VTITWE---IPTIDG----GAPVNNYIVEKR 23205

Query: 1222  EEVVHA-----DQSSCTFDNLSPGLEYNVSVYTVKDDK-----ESVPISDTI-IPEVPQL 1270
             E  + A      + S T   +S  +E  +  + V  +      E    SD + + EVP +
Sbjct: 23206 EAAMRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYGIGEPCETSDAVLVSEVPLV 23265

Query: 1271  -TDLSFVDITDSSIGLRW-TPL--NSSTIIGYRITVVAAGEGIPIFEDFVDSSVGYYTVT 1326
                L  VD+T S++ L W  PL    S + GY +    AG    +    +  +V  +TVT
Sbjct: 23266 PAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGTERWMKVVTLKPTVLEHTVT 23325

Query: 1327  GLEPGIDYDISVITLINGGESAP----TTLT-QQTAVPPPTDLRFTNIGPDTMRV----- 1376
              L  G  Y   +      G S P    T +T Q   V P  DL  + +   T+ V     
Sbjct: 23326 SLNEGEQYLFRIRAQNEKGVSEPRETVTAVTVQDLRVLPTIDL--STMPQKTIHVPAGRP 23383

Query: 1377  -------TWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSV 1429
                       PPP+     F       ++E    E     +   +  T +    EY + +
Sbjct: 23384 VELVIPIAGRPPPAASW--FFAGSKLRESERVTVETHTKVAKLTIRETTIRDTGEYTLEL 23441

Query: 1430  SSVY-EQHESTPLRGRQKTGLDSPTG-IDFSDITANSFTVHWIAPR----ATITGYRIRH 1483
              +V     E+  +    K G   PTG I   +I A S T+ W  P     A ++GY +  
Sbjct: 23442 KNVTGTTSETIKVIILDKPG--PPTGPIKIDEIDATSITISWEPPELDGGAPLSGYVVEQ 23499

Query: 1484  HPEHFSG-RPREDRVPHSRNSITLTNLTPGTEYVVSIVALN----GREESPLLIGQQST- 1537
                H  G  P  + V  +R++   T LT G EYV  + A N    G      +I  +S+ 
Sbjct: 23500 RDAHRPGWLPVSESV--TRSTFKFTRLTEGNEYVFRVAATNRFGIGSYLQSEVIECRSSI 23557

Query: 1538  -VSDVPRDLEVVAATPTSLLISWDAP----AVTVRYYRITYGETGGNSPVQEFTVPGSKS 1592
              +   P  L++   +   + ++W  P       V  Y +   E   +  V+   VP + +
Sbjct: 23558 RIPGPPETLQIFDVSRDGMTLTWYPPEDDGGSQVTGYIVERKEVRADRWVRVNKVPVTMT 23617

Query: 1593  TATISGLKPGVDYTITVYAVTGRGDSPAS--SKPI-SINYRTEIDKPSQMQVTDVQDNSI 1649
                 +GL  G++Y   V A+  RG    S  SKPI +++      KP   +VTD    S+
Sbjct: 23618 RYRSTGLTEGLEYEHRVTAINARGSGKPSRPSKPIVAMDPIAPPGKPQNPRVTDTTRTSV 23677

Query: 1650  SVKWL----PSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYA 1705
             S+ W        S VTGY +     +    TK  T      E T+  L    EY   V A
Sbjct: 23678 SLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTKCNTTPTKIREYTLTHLPQGAEYRFRVLA 23737

Query: 1706  QNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDS-IKIAWESPQGQVSRYRVTYSSPEDGI 1764
              N  G  +P        +   + L + D ++D   +      QG V R  +        I
Sbjct: 23738 CNAGGPGEPAEVPGTVKV--TEMLEYPDYELDERYQEGIFVRQGGVIRLTIPIKGKPFPI 23795

Query: 1765  HELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMES------------QPLIGTQSTA 1812
              +     +G +D ++   +     +T  V+   D  +S            +  +  +   
Sbjct: 23796 CKW--TKEG-QDISKRAMIATSETHTELVIKEADRGDSGTYDLVLENKCGKKAVYIKVRV 23852

Query: 1813  IPAPTD----LKFTQVTPTSLSAQWTPP----NVQLTGYRV--RVTPKEKTGPMKEINLA 1862
             I +P      L++  +   S+   W PP       + GY +  R  PK        I+  
Sbjct: 23853 IGSPNSPEGPLEYDDIQVRSVRVSWRPPADDGGADILGYILERREVPK---AAWYTIDSR 23909

Query: 1863  PDSSSVVVSGLMVATKYEVSVYALKDTLTSRP--AQGVVTTLENVSPP----RRARVTDA 1916
                +S+VV GL    +Y   V A      S+P  ++  VT    ++PP        V D 
Sbjct: 23910 VRGTSLVVKGLKENVEYHFRVSAENQFGISKPLKSEEPVTPKTPLNPPEPPSNPPEVLDV 23969

Query: 1917  TETTITISW-RTKTE---TITGFQVDAVPANGQTPIQRT-IKPDVRSYTITGLQPGTDYK 1971
             T++++++SW R K +    +TG+ ++    +    ++    +     YT+TGL P  +Y+
Sbjct: 23970 TKSSVSLSWSRPKDDGGSRVTGYYIERKETSTDKWVRHNKTQITTTMYTVTGLVPDAEYQ 24029

Query: 1972  IYLYTLND------NARSSPVVI-DASTAIDAPSNLRFLATTPNSLLVSWQPPRA----R 2020
               +   ND      +  S PVV  D       P  L  L+ + +S+ + W+ P       
Sbjct: 24030 FRIIAQNDVGLSETSPASEPVVCKDPFDKPSQPGELEILSISKDSVTLQWEKPECDGGKE 24089

Query: 2021  ITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRK 2080
             I GY ++Y + G    +   + R    + TI GL   TEY   V A      S P     
Sbjct: 24090 ILGYWVEYRQSGDSAWKKSNKERIKDKQFTIGGLLEATEYEFRVFAENETGLSRP----- 24144

Query: 2081  KTVQKTPFVTHPGYDTGNGIQLPGTSGQQPSVGQQM 2116
                            T   I+   TSG+ P + ++M
Sbjct: 24145 -------------RRTAMSIKTKLTSGEAPGIRKEM 24167



 Score =  157 bits (398), Expect = 9e-38
 Identities = 342/1617 (21%), Positives = 590/1617 (36%), Gaps = 235/1617 (14%)

Query: 624   NSHPIQWNAPQP---SHISKYILRWRPKNSVGRWKEAT-IPGHLNSYTIKGLKPGVVYEG 679
             N+  + W  P     S I+ Y +  R K S+ RW  A   P       + GL+ G  YE 
Sbjct: 14214 NTATVSWKRPVDDGGSEITGYHVERREKKSL-RWVRAIKTPVSDLRCKVTGLQEGSTYEF 14272

Query: 680   QLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVS 739
             ++ +  + G    +              S++V  +   + P   ++  VT+ T  S  ++
Sbjct: 14273 RVSAENRAGIGPPSE------------ASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLA 14320

Query: 740   W----VSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVN---IPDLLPGRKYIVNVYQ 792
             W          ++G+ VE++  + GDE    D   TA  +    +PDL    KY   +  
Sbjct: 14321 WGKPHYDGGLEITGYVVEHQ--KVGDEAWIKDTTGTALRITQFVVPDLQTKEKYNFRISA 14378

Query: 793   ISEDGE-QSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWS---RPQAPITGYRIVYSPS 848
             I++ G  +  ++   +    +  PD  +D     ++VVR     R   PI G     +P 
Sbjct: 14379 INDAGVGEPAVIPDVEIVEREMAPDFELDAELRRTLVVRAGLSIRIFVPIKGRP---APE 14435

Query: 849   VEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTV- 907
             V  +   +NL   AN      ++    + + I       ++   V+  E     +S  V 
Sbjct: 14436 VTWTKDNINLKNRAN------IENTESFTLLIIPECNRYDTGKFVMTIENPAGKKSGFVN 14489

Query: 908   ------PSP-RDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPGEHGQRLPI 956
                   P P  +L+  ++T   VT+ W  P     S +T Y V+                
Sbjct: 14490 VRVLDTPGPVLNLRPTDITKDSVTLHWDLPLIDGGSRITNYIVEKREATRKSYSTATTKC 14549

Query: 957   SRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDA----PTNLQFVNETDST 1012
              + T+ +VTGLS G  Y+F+V A +     +P    +  K       P +L  ++ T ST
Sbjct: 14550 HKCTY-KVTGLSEGCEYFFRVMAENEYGIGEPTETTEPVKASEAPSPPDSLNIMDITKST 14608

Query: 1013  VLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSVS-KYPLRNLQPASEYTVSLV 1067
             V + W  P+    ++ITGY   +   R+G  +  ++      +  +RNL    EYT  ++
Sbjct: 14609 VSLAWPKPKHDGGSKITGY--VIEAQRKGSDQWTHITTVKGLECVVRNLTEGEEYTFQVM 14666

Query: 1068  AIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWT-------------PAPRIG 1114
             A+     S         ++  + +P  +       +VI                P P + 
Sbjct: 14667 AVNSAGRSAPRESRPVIVKEQTMLPELDLRGIYQKLVIAKAGDNIKVEIPVLGRPKPTVT 14726

Query: 1115  FKLGVRP-SQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTP 1173
             +K G +   Q      E T+ S  + ++         Y +       E    I  +V   
Sbjct: 14727 WKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLTARNIVGEVGDVITIQVHDI 14786

Query: 1174  LSPPTNLHLEANPDTGVLTVSW---ERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQS 1230
               PPT         +  +T SW   E      I+ Y +    T+      L   V     
Sbjct: 14787 PGPPTGPIKFDEVSSDFVTFSWDPPENDGGVPISNYVVEMRQTDSTTWVELATTVIRTTY 14846

Query: 1231  SCTFDNLSPGLEYNVSVYTVKDDKESVPISDTII-----------PEVPQLTDLSFVDIT 1279
               T   L+ GLEY   V           I+   I           P  PQ+T      +T
Sbjct: 14847 KAT--RLTTGLEYQFRVKAQNRYGVGPGITSACIVANYPFKVPGPPGTPQVTA-----VT 14899

Query: 1280  DSSIGLRW-TPLNS--STIIGYRITVVAAGEGIPIFEDFVDSSV---GYYTVTGLEPGID 1333
               S+ + W  PL+   S I+GY    V   E   I    V  ++     +  +GL  GI 
Sbjct: 14900 KDSMTISWHEPLSDGGSPILGYH---VERKERNGILWQTVSKALVPGNIFKSSGLTDGIA 14956

Query: 1334  YDISVITLINGGESAPTTLTQQTA----VPPPTDLRFTNIGPDTMRVTWAPPP---SIDL 1386
             Y+  VI     G+S P+  ++       + PP      NI   T+ + WA P       +
Sbjct: 14957 YEFRVIAENMAGKSKPSKPSEPMLALDPIDPPGKPVPLNITRHTVTLKWAKPEYTGGFKI 15016

Query: 1387  TNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQ- 1445
             T+++V    + N   +     +  +N   ++ L     Y   V +       +P      
Sbjct: 15017 TSYIVEKRDLPNGRWLKANFSNILENEFTVSGLTEDAAYEFRVIAKNAAGAISPPSEPSD 15076

Query: 1446  ----KTGLDSP---TGIDFSDIT----ANSF------------TVHWIAPRATITGY-RI 1481
                 +  +++P     + F D        +F            T+ W      + G  ++
Sbjct: 15077 AITCRDDVEAPKIKVDVKFKDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKL 15136

Query: 1482  RHHPEHFSGR-PREDRVPHSRNSITLTNLTPG--TEYVVSIVALN--GREESPLLIGQQS 1536
                   FS     +D       + TLT   PG   +++ ++  L+  G  E PL + +  
Sbjct: 15137 EIKIADFSTNLVNKDSTRRDSGAYTLTATNPGGFAKHIFNVKVLDRPGPPEGPLAVTE-- 15194

Query: 1537  TVSDVPRDLEVVAATPTSLLISWDAP----AVTVRYYRITYGETGGNSPVQEFTVPGSKS 1592
                           T    ++SW  P       + +Y +   ET   +    +T   S+ 
Sbjct: 15195 -------------VTSEKCVLSWFPPLDDGGAKIDHYIVQKRETSRLA----WTNVASEV 15237

Query: 1593  TAT---ISGLKPGVDYTITVYAVTGRG-DSPASSKPI-SINYRTEIDKPSQMQVTDVQDN 1647
               T   ++ L  G +Y   V AV   G   P  S+P+ ++N     D P   +VT +  +
Sbjct: 15238 QVTKLKVTKLLKGNEYIFRVMAVNKYGVGEPLESEPVLAVNPYGPPDPPKNPEVTTITKD 15297

Query: 1648  SISVKW----LPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSV 1703
             S+ V W        S +  Y V    K G    K            + GL    EY   +
Sbjct: 15298 SMVVCWGHPDSDGGSEIINYIVERRDKAGQRWIKCNKKTLTDLRYKVSGLTEGHEYEFRI 15357

Query: 1704  YAQNPSGESQPLVQT-------AVTNIDRPKGLAFTDVDVDSIKIAWESP----QGQVSR 1752
              A+N +G S P   +        V     P      D    SI IAW  P      +++ 
Sbjct: 15358 MAENAAGISAPSPTSPFYKACDTVFKPGPPGNPRVLDTSRSSISIAWNKPIYDGGSEITG 15417

Query: 1753  YRVTYSSPEDGIHELFPAPDGEEDTA-ELQGLRPGSEYTVSVVALHDDMESQPLI--GT- 1808
             Y V  + PE+   ++   P G + T+  + GL    EY + + A++ +   +P +  GT 
Sbjct: 15418 YMVEIALPEEDEWQIVTPPAGLKATSYTITGLTENQEYKIRIYAMNSEGLGEPALVPGTP 15477

Query: 1809  --QSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSS 1866
               +   +P   +L        ++ A  T          +R+    K  P  E+  A D  
Sbjct: 15478 KAEDRMLPPEIELDADLRKVVTIRACCT----------LRLFVPIKGRPAPEVKWARDHG 15527

Query: 1867  SVVVSGLMVAT------------KYEVSVYAL--KDTLTSRPAQGVVTTLENVSPPRRAR 1912
               +    + +T            +++   Y L  +++  S+ A   V  L+   PP+  +
Sbjct: 15528 ESLDKASIESTSSYTLLIVGNVNRFDSGKYILTVENSSGSKSAFVNVRVLDTPGPPQDLK 15587

Query: 1913  VTDATETTITISWRTKT----ETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGT 1968
             V + T+T++T++W          I  + V+   +  +            S+ +  LQ G 
Sbjct: 15588 VKEVTKTSVTLTWDPPLLDGGSKIKNYIVEKRESTRKAYSTVATNCHKTSWKVDQLQEGC 15647

Query: 1969  DYKIYLYTLNDNARSSPVVIDASTAIDA------PSNLRFLATTPNSLLVSWQPPR---- 2018
              Y  Y   L +N     +  + + ++ A      P  +  +  T NS+ +SW+ P     
Sbjct: 15648 SY--YFRVLAENEYGIGLPAETAESVKASERPLPPGKITLMDVTRNSVSLSWEKPEHDGG 15705

Query: 2019  ARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEP 2075
             +RI GYI++ +  GS         +  VTEATITGL  G EY+  V A      S+P
Sbjct: 15706 SRILGYIVEMQTKGSDKWATCATVK--VTEATITGLIQGEEYSFRVSAQNEKGISDP 15760



 Score =  146 bits (368), Expect = 3e-34
 Identities = 363/1662 (21%), Positives = 600/1662 (36%), Gaps = 237/1662 (14%)

Query: 612  VEVFITETPSQPNSHPIQ----------WNAPQP---SHISKYILRWRPKNSVGRWKEAT 658
            VEV + + P  P +  I           WN P+    S I+ Y++  R  +S   W + +
Sbjct: 7404 VEVNVLDKPGPPAAFDITDVTNESCLLTWNPPRDDGGSKITNYVVERRATDSEV-WHKLS 7462

Query: 659  IPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPF 718
                  ++    L P   Y  ++ +   YG  E             PV ++ +T +    
Sbjct: 7463 STVKDTNFKATKLIPNKEYIFRVAAENMYGVGE-------------PVQASPITAKYQFD 7509

Query: 719  SPLVATSESVTEITASSFVVSWVSASDT----VSGFRVEYELSEEGDEPQYLDLPSTATS 774
             P   T    ++IT  +  ++W    D     ++G+ VE    +     +   +P   T+
Sbjct: 7510 PPGPPTRLEPSDITKDAVTLTWCEPDDDGGSPITGYWVERLDPDTDKWVRCNKMPVKDTT 7569

Query: 775  VNIPDLLPGRKYIVNVY--QISEDGEQSL----ILSTSQTTAPDAPPDPTVDQVDDTSIV 828
              +  L   +KY   V    ++  G+ S     IL       P  P  PTV  V  TS+ 
Sbjct: 7570 YRVKGLTNKKKYRFRVLAENLAGPGKPSKSTEPILIKDPIDPPWPPGKPTVKDVGKTSVR 7629

Query: 829  VRWSRPQ----APITGY--RIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYA 882
            + W++P+    A I  Y   ++ + + E       +P T +   L  L  G +Y+  + A
Sbjct: 7630 LNWTKPEHDGGAKIESYVIEMLKTGTDEWVRVAEGVPTTQH--LLPGLMEGQEYSFRVRA 7687

Query: 883  VEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYR 938
            V +  ES P           +      PR L+ + +T     + WT PE    S +T Y 
Sbjct: 7688 VNKAGESEPSEPSDPVLCREKLYPPSPPRWLEVINITKNTADLKWTVPEKDGGSPITNYI 7747

Query: 939  VDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSH-GR------ESKPLTA 991
            V+   V   G       + ++T   VT L+ G  Y F+V A +  G+      E   L  
Sbjct: 7748 VEKRDVRRKGWQTVDTTV-KDTKCTVTPLTEGSLYVFRVAAENAIGQSDYTEIEDSVLAK 7806

Query: 992  QQTTKLDAPTNLQFVNETDSTVLVRWTPPR--AQITGYRLTVGLTRRGQPRQYNVGPSVS 1049
               T    P  L  V+ T   V ++W PP+        R  +    R   R    G +  
Sbjct: 7807 DTFTTPGPPYALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKERLGTRWVKAGKTAG 7866

Query: 1050 KYPLRNLQPASEYTVSLVAIKGNQES-----PKATGVFTTLQPGS-SIPPYNTEVTET-- 1101
                  +    E T     ++   E+      + T + +   P S   PP +  VT+   
Sbjct: 7867 PDCNFRVTDVIEGTEVQFQVRAENEAGVGHPSEPTEILSIEDPTSPPSPPLDLHVTDAGR 7926

Query: 1102 -TIVITWTP------APRIGFKLGVRPSQGGEAPREVTS----DSGSIVVSGLTPGVEYV 1150
              I I W P      +P IG+ + + P  G E    V S    D    V  G+ P  EYV
Sbjct: 7927 KHIAIAWKPPEKNGGSPIIGYHVEMCP-VGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYV 7985

Query: 1151 YTIQVLRD-GQERDAPIVNKVVT--PLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYR 1207
              ++ +   G    + I   VV   P   PT + LE +    ++ +  E+ + P    +R
Sbjct: 7986 LRVRAVNAIGVSEPSEISENVVAKDPDCKPT-IDLETH---DIIVIEGEKLSIP--VPFR 8039

Query: 1208 ITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEY------NVSVYTV----KDDKESV 1257
                PT     +  +EV  +D+ +   D++S  LE       +  +YT+    K    + 
Sbjct: 8040 AVPVPTVSWHKDG-KEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATA 8098

Query: 1258 PISDTIIPEVPQLTDLSFVDITDSSIGLRWTPL---NSSTIIGYRITVVAAGEG--IPIF 1312
             I+  +I       D+   DIT SS  L W P      + I+ Y +    AG    IP+ 
Sbjct: 8099 SINVKVIGLPGPCKDIKASDITKSSCKLTWEPPEFDGGTPILHYVLERREAGRRTYIPVM 8158

Query: 1313 EDFVDSSVGYYTVTGLEPGIDY--DISVITLINGGESAP---TTLTQQTAVP--PPTDLR 1365
                  S   +TV  L P  +Y   +  +  + GGE        + Q    P  PP D+ 
Sbjct: 8159 SGENKLS---WTVKDLIPNGEYFFRVKAVNKVGGGEYIELKNPVIAQDPKQPPDPPVDVE 8215

Query: 1366 FTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLT----NLLP 1421
              N   + M +TW  PP  D  + ++ Y   K  +              +LT     L  
Sbjct: 8216 VHNPTAEAMTITW-KPPLYDGGSKIMGYIIEKIAKGEERWKRCNEHLVPILTYTAKGLEE 8274

Query: 1422 GTEYVVSVSSVYEQHESTPLRGRQKT----GLDSP---------------TGIDFSDITA 1462
            G EY   V +      S P R    T     +D+P                 +D S   +
Sbjct: 8275 GKEYQFRVRAENAAGISEPSRATPPTKAVDPIDAPKVILRTSLEVKRGDEIALDASISGS 8334

Query: 1463 NSFTVHWIAPRATITGYRIRHHPEHFSGRPR------EDRVPHSRNSITLTNLTPGTE-- 1514
               T+ WI     I    I+        R +      E  V      +++ N   G    
Sbjct: 8335 PYPTITWIKDENVIVPEEIKKRAAPLVRRRKGEVQEEEPFVLPLTQRLSIDNSKKGESQL 8394

Query: 1515 ------------YVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAP 1562
                        Y++ +   +G  ++P  +    T    P +        TS+L  W+ P
Sbjct: 8395 RVRDSLRPDHGLYMIKVENDHGIAKAPCTVSVLDTPGP-PINFVFEDIRKTSVLCKWEPP 8453

Query: 1563 -----AVTVRYYRITYGETGGNSPVQEFTVPGS---KSTATISGLKPGVDYTITVYAVTG 1614
                 +  + Y   T  +     P  E+ V  S       +++ L  G +Y   V A   
Sbjct: 8454 LDDGGSEIINY---TLEKKDKTKPDSEWIVVTSTLRHCKYSVTKLIEGKEYLFRVRAENR 8510

Query: 1615 RGDS-PASSKP-ISINYRTEIDKPSQMQVTDVQDNSISVKW---LPSSSPVTGYRVTTTP 1669
             G   P  SKP ++ +     D P +  V DV  NS+ VKW     + SP+ GY +    
Sbjct: 8511 FGPGPPCVSKPLVAKDPFGPPDAPDKPIVEDVTSNSMLVKWNEPKDNGSPILGYWLEKRE 8570

Query: 1670 KNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSG------ESQPLVQTAVTNI 1723
             N    ++   +  +  +  ++GL   + YV  V A+N +G       S P       + 
Sbjct: 8571 VNSTHWSRVNKSLLNALKANVDGLLEGLTYVFRVCAENAAGPGKFSPPSDPKTAHDPISP 8630

Query: 1724 DRPKGLAFTDVDVDSIKIAWESPQ----GQVSRYRVTYSSPEDGIHELFPAPDGEEDTAE 1779
              P     TD    +I++ WE P     G++  Y V       G +E     +      +
Sbjct: 8631 PGPPIPRVTDTSSTTIELEWEPPAFNGGGEIVGYFV--DKQLVGTNEWSRCTEKMIKVRQ 8688

Query: 1780 --LQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPN 1837
              ++ +R G++Y + V A++   E  P   TQ   +  P +    ++  +          
Sbjct: 8689 YTVKEIREGADYKLRVSAVNAAGEGPP-GETQPVTVAEPQEPPAVELDVS------VKGG 8741

Query: 1838 VQLTGYRVRVTPKEKTG---PMKEINLAP---DSSSVVVSGLMVATKYEVSVYALKDTLT 1891
            +Q+   +    P   TG   P K         D   VV+    V TK E+    +KD L 
Sbjct: 8742 IQIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKDRVVIDN--VGTKSEL---IIKDALR 8796

Query: 1892 SRPAQGVVTTLENVS---PPRRARVTDATETTI------------TISWRTKTE----TI 1932
                + V+T   +        R  V D     +             ++W    +     I
Sbjct: 8797 KDHGRYVITATNSCGSKFAAARVEVFDVPGPVLDLKPVVTNRKMCLLNWSDPEDDGGSEI 8856

Query: 1933 TGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDAST 1992
            TGF ++   A   T  ++ I+ +     ITGL  G +YK  +   N      PV I    
Sbjct: 8857 TGFIIERKDAKMHT-WRQPIETERSKCDITGLLEGQEYKFRVIAKNKFGCGPPVEIGPIL 8915

Query: 1993 AID------APSNLRFLATTPNSLLVSWQPPRAR----ITGYIIKYEKPGSPPREVVPRP 2042
            A+D      +P  L +   T +++ + W+ PR+     I GYII+  +   P  E V + 
Sbjct: 8916 AVDPLGPPTSPERLTYTERTKSTITLDWKEPRSNGGSPIQGYIIEKRRHDKPDFERVNKR 8975

Query: 2043 RPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQ 2084
                T   +  L+    Y   V A+    +SEP +     +Q
Sbjct: 8976 LCPTTSFLVENLDEHQMYEFRVKAVNEIGESEPSLPLNVVIQ 9017



 Score =  144 bits (362), Expect = 1e-33
 Identities = 288/1427 (20%), Positives = 522/1427 (36%), Gaps = 163/1427 (11%)

Query: 696   DFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYE 755
             D+T T+ ++  + +          P    S  + ++ +   ++SW    +        Y 
Sbjct: 12993 DYTITAENSSGSKSATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYI 13052

Query: 756   LSE-EGDEPQYLDLPSTA--TSVNIPDLLPGRKY-----IVNVYQISEDGEQSLILSTSQ 807
             + + E   P +  + +T   TS ++  L+ G +Y       N Y + +       ++ + 
Sbjct: 13053 VDKRETSRPNWAQVSATVPITSCSVEKLIEGHEYQFRICAENKYGVGDPVFTEPAIAKNP 13112

Query: 808   TTAPDAPPDPTVDQVDDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNL-PETA 862
                P     P +  +    + V W  P     +PITGY +    +   + T++N  P   
Sbjct: 13113 YDPPGRCDPPVISNITKDHMTVSWKPPADDGGSPITGYLLEKRETQAVNWTKVNRKPIIE 13172

Query: 863   NSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVK 922
              ++  + LQ G +Y   + A+ +     P    +             P   +  + T   
Sbjct: 13173 RTLKATGLQEGTEYEFRVTAINKAGPGKPSDASKAAYARDPQYPPGPPAFPKVYDTTRSS 13232

Query: 923   VTIMWTPPE----SAVTGYRVDVIPVNLPGEHGQRLPIS-RNTFAEVTGLSPGVTYYFKV 977
             V++ W  P     S + GY V+V   +        LP + + T  EVTGL     Y F+V
Sbjct: 13233 VSLSWGKPAYDGGSPIIGYLVEVKRADSDNWVRCNLPQNLQKTRFEVTGLMEDTQYQFRV 13292

Query: 978   FAVSHGRESKP-----------LTAQQTTKLDAPTNLQFVNETDST----VLVRWTPPRA 1022
             +AV+    S P           +      +LDA      +     T    V V+  PP  
Sbjct: 13293 YAVNKIGYSDPSDVPDKHYPKDILIPPEGELDADLRKTLILRAGVTMRLYVPVKGRPP-P 13351

Query: 1023  QITGYRLTVGLTRR-GQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGV 1081
             +IT  +  V L  R G   +     +  +    N   A +Y ++L    G +E      V
Sbjct: 13352 KITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKYILTLENSCGKKEYTIVVKV 13411

Query: 1082  FTTLQPGSSIPPYNTEVTETTIVITWTP------APRIGFKLGVRPSQGGEAPREVTSDS 1135
               T  PG  +     E+++ +  +TW P      +P I + +  R ++        T  S
Sbjct: 13412 LDT--PGPPVNVTVKEISKDSAYVTWEPPIIDGGSPIINYVVQKRDAERKSWSTVTTECS 13469

Query: 1136  -GSIVVSGLTPGVEYVYTIQVLRD------GQERDAPIVNKVVTPLSPPTNLHLEANPDT 1188
               S  V+ L  G  Y + +    +      G+ RDA  V    TP  P  +L + +   +
Sbjct: 13470 KTSFRVANLEEGKSYFFRVFAENEYGIGDPGETRDA--VKASQTP-GPVVDLKVRSVSKS 13526

Query: 1189  GVLTVSWERSTTPD---ITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNV 1245
                ++ W++  +     I GY +        + N  + V+ +     +  +L+ G EY  
Sbjct: 13527 S-CSIGWKKPHSDGGSRIIGYVVDFL----TEENKWQRVMKSLSLQYSAKDLTEGKEYTF 13581

Query: 1246  SVYTVKDDKESVPISDTIIP---------EVPQLTDLSFVDITDSSIGLR---------- 1286
              V    ++ E  P   T++          ++  L DL ++   +S+  L+          
Sbjct: 13582 RVSAENENGEGTPSEITVVARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPIKGKPAPS 13641

Query: 1287  --WTPLNSSTIIGYRITVVAAGEGIP-IFEDFVDSSVGYYTVTGLEPGIDYDISVITLIN 1343
               W           R++V ++      I  D   S  G YT+T        + ++   + 
Sbjct: 13642 VSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKEGTISIKVV 13701

Query: 1344  GGESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAPPP---SIDLTNFLVRYSPVKNEE 1400
             G    PT             ++F  +  + M + WAPP      ++TN+++      N +
Sbjct: 13702 GKPGIPT-----------GPIKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDSVNNK 13750

Query: 1401  DVAELSISPSDNAVVLTNLLPGTEYVVSVSS-----VYEQHESTPLRGRQKTGL-DSPTG 1454
              V   S +       +T L  G EY   VS+     V E  +S P+  R    + D+P  
Sbjct: 13751 WVTCAS-AVQKTTFRVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVPDAPPP 13809

Query: 1455  IDFSDITANSFTVHWIAPRAT----ITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLT 1510
              +  D+  +S ++ W  P+ T    ITGY +     +     R ++ P       +T LT
Sbjct: 13810 PNIVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTPIRMRDFKVTGLT 13869

Query: 1511  PGTEYVVSIVALN----GREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAV-- 1564
              G EY   ++A+N    G+   P          D P   EV+  T  S+ + W  P    
Sbjct: 13870 EGLEYEFRVMAINLAGVGKPSLPSEPVVALDPIDPPGKPEVINITRNSVTLIWTEPKYDG 13929

Query: 1565  --TVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASS 1622
                +  Y +   +    S ++   V   +   T++ L  G  Y   + A    G   A S
Sbjct: 13930 GHKLTGYIVEKRDLPSKSWMKANHVNVPECAFTVTDLVEGGKYEFRIRAKNTAGAISAPS 13989

Query: 1623  KPI-SINYRTEIDKPSQMQVTDVQD------------NSISV--KWLPSSS-PVTGYRVT 1666
             +   +I  + E + P+ +    ++D            N+IS+  K LP SS    G  + 
Sbjct: 13990 ESTETIICKDEYEAPTIVLDPTIKDGLTIKAGDTIVLNAISILGKPLPKSSWSKAGKDIR 14049

Query: 1667  TTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRP 1726
                   P      T+ P  + +TI+          ++ A NP G     V+  V ++  P
Sbjct: 14050 ------PSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFGTKVEHVKVTVLDVPGP 14103

Query: 1727  KG-LAFTDVDVDSIKIAWESP---QGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQG 1782
              G +  ++V  +   + W  P    G   +  +        +     + D +        
Sbjct: 14104 PGPVEISNVSAEKATLTWTPPLEDGGSPIKSYILEKRETSRLLWTVVSEDIQSCRHVATK 14163

Query: 1783  LRPGSEYTVSVVALH-----DDMESQPLIGTQSTAIPAPTDL-KFTQVTPTSLSAQWTPP 1836
             L  G+EY   V A++     + ++S+P+        P P +  + + VT  + +  W  P
Sbjct: 14164 LIQGNEYIFRVSAVNHYGKGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSWKRP 14223

Query: 1837  ----NVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTS 1892
                   ++TGY V    K+    ++ I          V+GL   + YE  V A       
Sbjct: 14224 VDDGGSEITGYHVERREKKSLRWVRAIKTPVSDLRCKVTGLQEGSTYEFRVSAENRAGIG 14283

Query: 1893  RPAQGVVTTLEN-----VSPPRRARVTDATETTITISWRTKTE----TITGFQVDAVPAN 1943
              P++   + L         PP    VTD T+ + +++W          ITG+ V+     
Sbjct: 14284 PPSEASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLAWGKPHYDGGLEITGYVVEHQKVG 14343

Query: 1944  GQTPIQRTIKPDVR--SYTITGLQPGTDYKIYLYTLNDNARSSPVVI 1988
              +  I+ T    +R   + +  LQ    Y   +  +ND     P VI
Sbjct: 14344 DEAWIKDTTGTALRITQFVVPDLQTKEKYNFRISAINDAGVGEPAVI 14390



 Score =  136 bits (342), Expect = 3e-31
 Identities = 287/1435 (20%), Positives = 516/1435 (35%), Gaps = 196/1435 (13%)

Query: 794   SEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ----APITGYRIVYSPSV 849
             +  G +S  +       P  P    ++++     ++ W  P     + IT Y +    + 
Sbjct: 13000 NSSGSKSATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYIVDKRETS 13059

Query: 850   EGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPS 909
               +  +++      S ++  L  G +Y   I A  +     PV  +      P     P 
Sbjct: 13060 RPNWAQVSATVPITSCSVEKLIEGHEYQFRICAENKYGVGDPVFTEPAIAKNPYDP--PG 13117

Query: 910   PRDLQFVE-VTDVKVTIMWTPPE----SAVTGYRVDVIPVNLPG-EHGQRLPISRNTFAE 963
               D   +  +T   +T+ W PP     S +TGY ++             R PI   T  +
Sbjct: 13118 RCDPPVISNITKDHMTVSWKPPADDGGSPITGYLLEKRETQAVNWTKVNRKPIIERTL-K 13176

Query: 964   VTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKL-------DAPTNLQFVNETDSTVLVR 1016
              TGL  G  Y F+V A++     KP  A +             P   +  + T S+V + 
Sbjct: 13177 ATGLQEGTEYEFRVTAINKAGPGKPSDASKAAYARDPQYPPGPPAFPKVYDTTRSSVSLS 13236

Query: 1017  WTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSVSK--YPLRNLQPASEYTVSLVAIK 1070
             W  P     + I GY + V         + N+  ++ K  + +  L   ++Y   + A+ 
Sbjct: 13237 WGKPAYDGGSPIIGYLVEVKRADSDNWVRCNLPQNLQKTRFEVTGLMEDTQYQFRVYAVN 13296

Query: 1071  GNQESPKATGVFTTLQPGSSIPP---YNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEA 1127
                 S  +            IPP    + ++ +T I+       R G  + +     G  
Sbjct: 13297 KIGYSDPSDVPDKHYPKDILIPPEGELDADLRKTLIL-------RAGVTMRLYVPVKGRP 13349

Query: 1128  PREVTSDSGSIVVS---GLT------------------PGVEYVYTIQVLRDGQERDAPI 1166
             P ++T    ++ +    GL                      +Y+ T++      +++  I
Sbjct: 13350 PPKITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKYILTLE--NSCGKKEYTI 13407

Query: 1167  VNKVVTPLSPPTNLHL-EANPDTGVLTVSWERSTTPDITG----YRITTTPTNGQQGNSL 1221
             V KV+    PP N+ + E + D+  +T  WE    P I G            + ++ +  
Sbjct: 13408 VVKVLDTPGPPVNVTVKEISKDSAYVT--WE---PPIIDGGSPIINYVVQKRDAERKSWS 13462

Query: 1222  EEVVHADQSSCTFDNLSPGLEYNVSVYTVKD--------DKESVPISDTIIPEVPQLTDL 1273
                    ++S    NL  G  Y   V+   +         +++V  S T  P V    DL
Sbjct: 13463 TVTTECSKTSFRVANLEEGKSYFFRVFAENEYGIGDPGETRDAVKASQTPGPVV----DL 13518

Query: 1274  SFVDITDSSIGLRWTPLNS---STIIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEP 1330
                 ++ SS  + W   +S   S IIGY +  +        ++  + S    Y+   L  
Sbjct: 13519 KVRSVSKSSCSIGWKKPHSDGGSRIIGYVVDFLTEENK---WQRVMKSLSLQYSAKDLTE 13575

Query: 1331  GIDYDISVITLINGGESAPTTLT---QQTAVPPPTDLRFTNIGPDT-------------M 1374
             G +Y   V      GE  P+ +T   +   V P  DL+     PD              +
Sbjct: 13576 GKEYTFRVSAENENGEGTPSEITVVARDDVVAPDLDLKGL---PDLCYLAKENSNFRLKI 13632

Query: 1375  RVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLL-------PGTEYVV 1427
              +   P PS+         S  K E+ +A  +    +++ V T L+          +Y +
Sbjct: 13633 PIKGKPAPSV---------SWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTI 13683

Query: 1428  SVSSVYEQHEST-PLRGRQKTGLDSPTG-IDFSDITANSFTVHWIAPR----ATITGYRI 1481
             ++ +V    E T  ++   K G+  PTG I F ++TA + T+ W  P+    + IT Y I
Sbjct: 13684 TLKNVAGTKEGTISIKVVGKPGI--PTGPIKFDEVTAEAMTLKWAPPKDDGGSEITNY-I 13740

Query: 1482  RHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN------GREESPLLIGQQ 1535
                 +  + +         + +  +T L  G EY   + A N      G +  P++    
Sbjct: 13741 LEKRDSVNNKWVTCASAVQKTTFRVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHP 13800

Query: 1536  STVSDVPRDLEVVAATPTSLLISWDAPAVT----VRYYRITYGETGGNSPVQEFTVPGSK 1591
               V D P    +V     S+ ++W  P  T    +  Y + + E       +    P   
Sbjct: 13801 FDVPDAPPPPNIVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTPIRM 13860

Query: 1592  STATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISV 1651
                 ++GL  G++Y   V A+   G    S     +     ID P + +V ++  NS+++
Sbjct: 13861 RDFKVTGLTEGLEYEFRVMAINLAGVGKPSLPSEPVVALDPIDPPGKPEVINITRNSVTL 13920

Query: 1652  KWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQN 1707
              W          +TGY V           K       +   T+  L    +Y   + A+N
Sbjct: 13921 IWTEPKYDGGHKLTGYIVEKRDLPSKSWMKANHVNVPECAFTVTDLVEGGKYEFRIRAKN 13980

Query: 1708  PSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQV----------------S 1751
              +G      ++  T I + +  A T V   +IK       G                  S
Sbjct: 13981 TAGAISAPSESTETIICKDEYEAPTIVLDPTIKDGLTIKAGDTIVLNAISILGKPLPKSS 14040

Query: 1752  RYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQST 1811
               +         I ++   P     T +    +   EYT++             +     
Sbjct: 14041 WSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFGTKVEHVKVTVLDV 14100

Query: 1812  AIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVR--VTPKEKTGPMKEINLAPDSSSV- 1868
               P P  ++ + V+    +  WTPP ++  G  ++  +  K +T  +    ++ D  S  
Sbjct: 14101 PGP-PGPVEISNVSAEKATLTWTPP-LEDGGSPIKSYILEKRETSRLLWTVVSEDIQSCR 14158

Query: 1869  -VVSGLMVATKYEVSVYALKDTLTSRPAQG----VVTTLENVSPPRRARVTDATETTITI 1923
              V + L+   +Y   V A+       P Q     +V       PP +  V++ T+ T T+
Sbjct: 14159 HVATKLIQGNEYIFRVSAVNHYGKGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTATV 14218

Query: 1924  SWRTKTE----TITGFQVDAVPANGQTPIQRTIKPDVRSY--TITGLQPGTDYKIYLYTL 1977
             SW+   +     ITG+ V+         + R IK  V      +TGLQ G+ Y+  +   
Sbjct: 14219 SWKRPVDDGGSEITGYHVERREKKSLRWV-RAIKTPVSDLRCKVTGLQEGSTYEFRVSAE 14277

Query: 1978  N-------DNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYII 2026
             N         A  S ++ DA+     PSN     TT  S  ++W  P       ITGY++
Sbjct: 14278 NRAGIGPPSEASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLAWGKPHYDGGLEITGYVV 14337

Query: 2027  KYEKPGSPPREVVPRPRPG----VTEATITGLEPGTEYTIYVIALKNNQKSEPLI 2077
             +++K G    E   +   G    +T+  +  L+   +Y   + A+ +    EP +
Sbjct: 14338 EHQKVGD---EAWIKDTTGTALRITQFVVPDLQTKEKYNFRISAINDAGVGEPAV 14389



 Score =  133 bits (335), Expect = 2e-30
 Identities = 325/1621 (20%), Positives = 584/1621 (36%), Gaps = 231/1621 (14%)

Query: 628   IQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISI 684
             + W  P     S I+ Y+L  R   +V   K    P    +    GL+ G  YE ++ +I
Sbjct: 13134 VSWKPPADDGGSPITGYLLEKRETQAVNWTKVNRKPIIERTLKATGLQEGTEYEFRVTAI 13193

Query: 685   QQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSW---- 740
              + G  + +              S         + P       V + T SS  +SW    
Sbjct: 13194 NKAGPGKPSD------------ASKAAYARDPQYPPGPPAFPKVYDTTRSSVSLSWGKPA 13241

Query: 741   VSASDTVSGFRVEYELSEEGDEPQYLDLPSTA--TSVNIPDLLPGRKYIVNVYQISEDGE 798
                   + G+ VE + ++  D     +LP     T   +  L+   +Y   VY +++ G 
Sbjct: 13242 YDGGSPIIGYLVEVKRADS-DNWVRCNLPQNLQKTRFEVTGLMEDTQYQFRVYAVNKIGY 13300

Query: 799   QSLILSTSQTTAPDA--------PPDPTVDQVDDTSIVVRWS---RPQAPITGYRIVYSP 847
                   +  +  PD         PP+  +D     ++++R     R   P+ G      P
Sbjct: 13301 ------SDPSDVPDKHYPKDILIPPEGELDADLRKTLILRAGVTMRLYVPVKGRP---PP 13351

Query: 848   SVEGSSTELNLPETAN-SVTLSDLQPGVQ-----------YNITIYAVEENQESTPVVIQ 895
              +  S   +NL +     +  +D    ++           Y +T+      +E T VV  
Sbjct: 13352 KITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKYILTLENSCGKKEYTIVVKV 13411

Query: 896   QETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPGEHG 951
              +T G P + TV         E++     + W PP     S +  Y V            
Sbjct: 13412 LDTPGPPVNVTVK--------EISKDSAYVTWEPPIIDGGSPIINYVVQKRDAERKSWST 13463

Query: 952   QRLPISRNTFAEVTGLSPGVTYYFKVFAVSH---GRESKPLTAQQTTKLDAPT-NLQFVN 1007
                  S+ +F  V  L  G +Y+F+VFA +    G   +   A + ++   P  +L+  +
Sbjct: 13464 VTTECSKTSF-RVANLEEGKSYFFRVFAENEYGIGDPGETRDAVKASQTPGPVVDLKVRS 13522

Query: 1008  ETDSTVLVRWTPPRA----QITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYT 1063
              + S+  + W  P +    +I GY +   LT   + ++     S+ +Y  ++L    EYT
Sbjct: 13523 VSKSSCSIGWKKPHSDGGSRIIGYVVDF-LTEENKWQRVMKSLSL-QYSAKDLTEGKEYT 13580

Query: 1064  VSLVAIKGNQE-SPKATGVFT---TLQPG---SSIPPYNTEVTETT-----IVITWTPAP 1111
               + A   N E +P    V      + P      +P       E +     I I   PAP
Sbjct: 13581 FRVSAENENGEGTPSEITVVARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPIKGKPAP 13640

Query: 1112  RIGFKLGVRP-SQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKV 1170
              + +K G  P +       E ++ + +++V          YTI +      ++  I  KV
Sbjct: 13641 SVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKEGTISIKV 13700

Query: 1171  VTPLSPPTNLHLEANPDTGVLTVSW---ERSTTPDITGYRITTTPTNGQQGNSLEEVVHA 1227
             V     PT            +T+ W   +     +IT Y +    +   +  +    V  
Sbjct: 13701 VGKPGIPTGPIKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDSVNNKWVTCASAVQK 13760

Query: 1228  DQSSCTFDNLSPGLEYNVSV-----YTVKDDKESVPI---SDTIIPEVPQLTDLSFVDIT 1279
                  T   L  G+EY   V     Y V +  +S PI       +P+ P   ++  VD+ 
Sbjct: 13761 TTFRVT--RLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVPDAPPPPNI--VDVR 13816

Query: 1280  DSSIGLRWTP---LNSSTIIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDI 1336
               S+ L WT       S I GY +        +    +     +  + VTGL  G++Y+ 
Sbjct: 13817 HDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTPIRMRDFKVTGLTEGLEYEF 13876

Query: 1337  SVITLINGGESAPTTLTQQTA----VPPPTDLRFTNIGPDTMRVTWAPPP---SIDLTNF 1389
              V+ +   G   P+  ++       + PP      NI  +++ + W  P       LT +
Sbjct: 13877 RVMAINLAGVGKPSLPSEPVVALDPIDPPGKPEVINITRNSVTLIWTEPKYDGGHKLTGY 13936

Query: 1390  LVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVV---------SVSSVYEQHESTP 1440
             +V    + ++  +    ++  + A  +T+L+ G +Y           ++S+  E  E+  
Sbjct: 13937 IVEKRDLPSKSWMKANHVNVPECAFTVTDLVEGGKYEFRIRAKNTAGAISAPSESTETII 13996

Query: 1441  LRGRQK--TGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVP 1498
              +   +  T +  PT  D   I A    V       +I G  +   P+    +  +D  P
Sbjct: 13997 CKDEYEAPTIVLDPTIKDGLTIKAGDTIV---LNAISILGKPL---PKSSWSKAGKDIRP 14050

Query: 1499  HSRNSITLTNLTP-----------GTEYVVSIVALNGREESPLLIGQQSTVSDVPRD--- 1544
                  IT T  +              EY ++     G +   + +    TV DVP     
Sbjct: 14051 SDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFGTKVEHVKV----TVLDVPGPPGP 14106

Query: 1545  LEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATI-------- 1596
             +E+   +     ++W  P            E GG SP++ + +   +++  +        
Sbjct: 14107 VEISNVSAEKATLTWTPPL-----------EDGG-SPIKSYILEKRETSRLLWTVVSEDI 14154

Query: 1597  -------SGLKPGVDYTITVYAVT--GRGDSPASSKPISINYRT-EIDKPSQMQVTDVQD 1646
                    + L  G +Y   V AV   G+G+ P  S+P+ +  R      P + +V++V  
Sbjct: 14155 QSCRHVATKLIQGNEYIFRVSAVNHYGKGE-PVQSEPVKMVDRFGPPGPPEKPEVSNVTK 14213

Query: 1647  NSISVKWL----PSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVS 1702
             N+ +V W        S +TGY V    K      +            + GLQ    Y   
Sbjct: 14214 NTATVSWKRPVDDGGSEITGYHVERREKKSLRWVRAIKTPVSDLRCKVTGLQEGSTYEFR 14273

Query: 1703  VYAQNPSGESQP-------LVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQG----QVS 1751
             V A+N +G   P       L++ A      P     TD    S  +AW  P      +++
Sbjct: 14274 VSAENRAGIGPPSEASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLAWGKPHYDGGLEIT 14333

Query: 1752  RYRVTYSSPEDGIHELFPAPDGEEDTA-ELQGLRPGSEYTVSVVALHDDMESQPLIGTQS 1810
              Y V +    D              T   +  L+   +Y   + A++D    +P +    
Sbjct: 14334 GYVVEHQKVGDEAWIKDTTGTALRITQFVVPDLQTKEKYNFRISAINDAGVGEPAV---- 14389

Query: 1811  TAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDS----- 1865
               IP    ++        L A+     V   G  +R+    K  P  E+    D+     
Sbjct: 14390 --IPDVEIVEREMAPDFELDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKN 14447

Query: 1866  -------SSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTT--LENVSPPRRARVTDA 1916
                     S  +  +    +Y+   + +     +    G V    L+   P    R TD 
Sbjct: 14448 RANIENTESFTLLIIPECNRYDTGKFVMTIENPAGKKSGFVNVRVLDTPGPVLNLRPTDI 14507

Query: 1917  TETTITISWRTKT----ETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKI 1972
             T+ ++T+ W          IT + V+   A  ++    T K    +Y +TGL  G +Y  
Sbjct: 14508 TKDSVTLHWDLPLIDGGSRITNYIVEKREATRKSYSTATTKCHKCTYKVTGLSEGCEYFF 14567

Query: 1973  YLYTLNDNARSSPVV----IDASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGY 2024
              +   N+     P      + AS A   P +L  +  T +++ ++W  P+    ++ITGY
Sbjct: 14568 RVMAENEYGIGEPTETTEPVKASEAPSPPDSLNIMDITKSTVSLAWPKPKHDGGSKITGY 14627

Query: 2025  IIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQ 2084
             +I+ ++ GS     +   +    E  +  L  G EYT  V+A+ +  +S P   R   V+
Sbjct: 14628 VIEAQRKGSDQWTHITTVKG--LECVVRNLTEGEEYTFQVMAVNSAGRSAPRESRPVIVK 14685

Query: 2085  K 2085
             +
Sbjct: 14686 E 14686



 Score =  128 bits (322), Expect = 6e-29
 Identities = 343/1604 (21%), Positives = 574/1604 (35%), Gaps = 260/1604 (16%)

Query: 611   PVEVFITETPSQPNSHPIQWNAPQ---PSHISKYILRWRPKNSVGRWKEATIPGHLNS-- 665
             P ++ I +  S  +S  + W+ P     S ++ Y++  R +     W   +  G + +  
Sbjct: 20798 PAKIRIAD--STKSSITLGWSKPVYDGGSAVTGYVVEIR-QGEEEEWTTVSTKGEVRTTE 20854

Query: 666   YTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATS 725
             Y +  LKPGV Y  ++ ++   G  E    +    +                 S +    
Sbjct: 20855 YVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQAKDILEAPEIDLDVALRTSVIAKAG 20914

Query: 726   ESVTEITASSF----VVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLL 781
             E V  +          V+W      + G    Y + E  D    L +P    +       
Sbjct: 20915 EDVQVLIPFKGRPPPTVTWRKDEKNL-GSDARYSI-ENTDSSSLLTIPQVTRNDT----- 20967

Query: 782   PGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ----AP 837
                KYI+ +     + + S + S      P A     V  V   ++ + W  P     +P
Sbjct: 20968 --GKYILTIENGVGEPKSSTV-SVKVLDTPAACQKLQVKHVSRGTVTLLWDPPLIDGGSP 21024

Query: 838   ITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQE 897
             I  Y I    + + + + ++   ++ S  L DL     +   + A  E     P     E
Sbjct: 21025 IINYVIEKRDATKRTWSVVSHKCSSTSFKLIDLSEKTPFFFRVLAENEIGIGEPC----E 21080

Query: 898   TTGTPRSDTVPSP-RDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPVNLPGEHG- 951
             TT   ++  VP+P RDL   + T   V + WT P+    S +T Y   V+     GE   
Sbjct: 21081 TTEPVKAAEVPAPIRDLSMKDSTKTSVILSWTKPDFDGGSVITEY---VVERKGKGEQTW 21137

Query: 952   QRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDS 1011
                 IS+    EV+ L       F+VFA +    S P+T    T  +    L    E D 
Sbjct: 21138 SHAGISKTCEIEVSQLKEQSVLEFRVFAKNEKGLSDPVTIGPITVKE----LIITPEVDL 21193

Query: 1012  TVLVRWTPPRAQIT---GYRLTVGLTRRGQPRQYNVGPSVS----KYPLRNLQ------P 1058
             + +     P AQ+T   G+ + + L  +G+P+     PS+S      PL+  +       
Sbjct: 21194 SDI-----PGAQVTVRIGHNVHLELPYKGKPK-----PSISWLKDGLPLKESEFVRFSKT 21243

Query: 1059  ASEYTVSLVAIKGNQESPKATGVFT-------------TLQPGSSI--PPYNTEVTETTI 1103
              ++ T+S+   K  +   K T +               TL P S    P    E+   ++
Sbjct: 21244 ENKITLSIKNAK-KEHGGKYTVILDNAVCRIAVPITVITLGPPSKPKGPIRFDEIKADSV 21302

Query: 1104  VITWTPAPRIGFKLGVRPSQGGEAP------REVTSDSGSIVVSG----------LTPGV 1147
             +++W      G         GGE        RE +  +  +V S           L    
Sbjct: 21303 ILSWDVPEDNG---------GGEITCYSIEKRETSQTNWKMVCSSVARTTFKVPNLVKDA 21353

Query: 1148  EYVYTIQVLRDGQERDAPIVNKVVTP-----LSPPTNLHLEANPDTGVLTVSWERSTTP- 1201
             EY + ++   +      P+V+ ++       +  P    +  N  +  ++++W+      
Sbjct: 21354 EYQFRVRA-ENRYGVSQPLVSSIIVAKHQFRIPGPPGKPVIYNVTSDGMSLTWDAPVYDG 21412

Query: 1202  --DITGYRITTTPTNG---QQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKES 1256
               ++TG+ +     N    Q+ N+    +   +   T   L  GL+Y   VY       S
Sbjct: 21413 GSEVTGFHVEKKERNSILWQKVNT--SPISGREYRAT--GLVEGLDYQFRVYAENSAGLS 21468

Query: 1257  VPISDT-----IIPEVPQLTDLSFVDITDSSIGLRWTPL---NSSTIIGYRITVVAAGEG 1308
              P   +     + P  P  T   ++D+T  +I L+W P      S I+GY I      E 
Sbjct: 21469 SPSDPSKFTLAVSPVDPPGTP-DYIDVTRETITLKWNPPLRDGGSKIVGYSIEKRQGNER 21527

Query: 1309  IPIFEDFVDSSVGYYTVTGLEPGIDYDISVI------TLINGGESAPTTLTQQTAVPPPT 1362
               +  +F D S   YTVTGL PG  Y+  +I      T+    +S+   +T+   VPP  
Sbjct: 21528 W-VRCNFTDVSECQYTVTGLSPGDRYEFRIIARNAVGTISPPSQSSGIIMTRDENVPP-- 21584

Query: 1363  DLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNE---EDVAELSISPSDNAVVLTNL 1419
                    GP+                 LV+  PV      +D  E+    +   + +T++
Sbjct: 21585 ---IVEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMN---MEITDV 21638

Query: 1420  LPGTEYVV--------SVSSVYEQHESTPLRGRQKTGLDSPTG-----IDFSDITANSFT 1466
             L  T   V         V +V  ++ S   +   K  +    G     I F++IT    T
Sbjct: 21639 LGSTSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQDTPGKVVGPIRFTNITGEKMT 21698

Query: 1467  VHWIAPR----ATITGYRI-RHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVA 1521
             + W AP     A IT Y I +      +    ED+      S T   L  G EY   + A
Sbjct: 21699 LWWDAPLNDGCAPITHYIIEKRETSRLAWALIEDKC--EAQSYTAIKLINGNEYQFRVSA 21756

Query: 1522  LN----GR--EESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGE 1575
             +N    GR  +  P++   Q TV D P   E    T  S+ ++W  P            E
Sbjct: 21757 VNKFGVGRPLDSDPVVAQIQYTVPDAPGIPEPSNITGNSITLTWARP------------E 21804

Query: 1576  TGGNSPVQEFTV-----------------PGSKSTATISGLKPGVDYTITVYAVTGRGDS 1618
             + G S +Q++ +                 P S++   ++GL  G +Y   V A    G  
Sbjct: 21805 SDGGSEIQQYILERREKKSTRWVKVISKRPISETRFKVTGLTEGNEYEFHVMAENAAGVG 21864

Query: 1619  PASSKPISINYRTEIDKPSQ---MQVTDVQDNSISVKW----LPSSSPVTGYRVTTTPKN 1671
             PAS     I  R  ++ P     ++VTD    ++S++W          + GY +     +
Sbjct: 21865 PASGISRLIKCREPVNPPGPPTVVKVTDTSKTTVSLEWSKPVFDGGMEIIGYIIEMCKAD 21924

Query: 1672  GPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTA-VTNIDRPKGLA 1730
                  K       +T  T+  LQ   EY   V A N +G+      T  +  +DR   L 
Sbjct: 21925 LGDWHKVNAEACVKTRYTVTDLQAGEEYKFRVSAINGAGKGDSCEVTGTIKAVDR---LT 21981

Query: 1731  FTDVDVDS-IKIAWESPQGQVSRYRVTY----------SSPEDGIH---ELFPAPDGEED 1776
               ++D+D+  K       G   R  + Y          S P+  +    ++         
Sbjct: 21982 APELDIDANFKQTHVVRAGASIRLFIAYQGRPTPTAVWSKPDSNLSLRADIHTTDSFSTL 22041

Query: 1777  TAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPP 1836
             T E        +YT++V            +    T  P P  + F  VT  S +  W  P
Sbjct: 22042 TVENCNRNDAGKYTLTVENNSGSKSITFTVKVLDTPGP-PGPITFKDVTRGSATLMWDAP 22100

Query: 1837  NVQLTGYRVRVTPKEKTGPMKE----INLAPDSSSVVVSGLMVATKYEVSVYALKDTLTS 1892
              +   G R+     EK    +     I+         V+ L     Y   V A+ +    
Sbjct: 22101 LLD-GGARIHHYVVEKREASRRSWQVISEKCTRQIFKVNDLAEGVPYYFRVSAVNEYGVG 22159

Query: 1893  RPAQ--GVVTTLENVSPPRRARVTDATETTITISW----RTKTETITGFQVDAVPANGQT 1946
              P +    +   E  +PPRR  V D ++++  ++W          ITG+ ++        
Sbjct: 22160 EPYEMPEPIVATEQPAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSDF 22219

Query: 1947  PIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATT 2006
              ++      + ++T+  L   T+Y+  +   ND   S P    +S  I  P         
Sbjct: 22220 WVEAGHTKQL-TFTVERLVEKTEYEFRVKAKNDAGYSEPREAFSSVIIKEPQ------IE 22272

Query: 2007  PNSLLVSWQPPRARITGYIIKYEKPGSPPREVVP---RPRPGVT 2047
             P + L         IT  +I   K GSP    VP   RP P VT
Sbjct: 22273 PTADLTG-------ITNQLITC-KAGSPFTIDVPISGRPAPKVT 22308



 Score =  124 bits (311), Expect = 1e-27
 Identities = 291/1338 (21%), Positives = 513/1338 (38%), Gaps = 174/1338 (13%)

Query: 780   LLPGRKYI-----VNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRP 834
             ++ G +YI     VN Y I E  E   +++ +    P  P  P V ++   S+ V WSRP
Sbjct: 20658 IIKGNEYIFRVRAVNKYGIGEPLESDSVVAKNAFVTPGPPGIPEVTKITKNSMTVVWSRP 20717

Query: 835   QA----PITGYRIVYSPSVEGSSTEL---NLPETANSVTLSDLQPGVQYNI-TIYAVEEN 886
              A     I+GY +           ++    + +T   VT        QY +  + A  + 
Sbjct: 20718 IADGGSDISGYFLEKRDKKSLGWFKVLKETIRDTRQKVTGLTENSDYQYRVCAVNAAGQG 20777

Query: 887   QESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVI 942
               S P    +        D    P  ++  + T   +T+ W+ P     SAVTGY V++ 
Sbjct: 20778 PFSEP---SEFYKAADPIDPPGPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVVEI- 20833

Query: 943   PVNLPGEHGQRLPIS-----RNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTK- 996
                  GE  +   +S     R T   V+ L PGV YYF+V AV+   + +P+   +  + 
Sbjct: 20834 ---RQGEEEEWTTVSTKGEVRTTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQA 20890

Query: 997   ---LDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQP--------RQYNVG 1045
                L+AP       E D  V +R T   A+  G  + V +  +G+P         + N+G
Sbjct: 20891 KDILEAP-------EIDLDVALR-TSVIAK-AGEDVQVLIPFKGRPPPTVTWRKDEKNLG 20941

Query: 1046  PSVSKYPLRNLQPASEYTVS----------LVAIKGNQESPKATGVFTTL--QPGSSIPP 1093
              S ++Y + N   +S  T+           ++ I+     PK++ V   +   P +    
Sbjct: 20942 -SDARYSIENTDSSSLLTIPQVTRNDTGKYILTIENGVGEPKSSTVSVKVLDTPAACQKL 21000

Query: 1094  YNTEVTETTIVITWTP------APRIGFKLGVRPS---QGGEAPREVTSDSGSIV-VSGL 1143
                 V+  T+ + W P      +P I + +  R +          + +S S  ++ +S  
Sbjct: 21001 QVKHVSRGTVTLLWDPPLIDGGSPIINYVIEKRDATKRTWSVVSHKCSSTSFKLIDLSEK 21060

Query: 1144  TPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDI 1203
             TP    V     +  G+  +     K     +P  +L ++ +  T V+ +SW   T PD 
Sbjct: 21061 TPFFFRVLAENEIGIGEPCETTEPVKAAEVPAPIRDLSMKDSTKTSVI-LSW---TKPDF 21116

Query: 1204  TGYRITTTPTNGQQGNSLEEVVHADQS-SCTFD----NLSPGLEYNVSVYTVKDDKESVP 1258
              G  + T     ++G   +   HA  S +C  +         LE+ V     K   + V 
Sbjct: 21117 DGGSVITEYVVERKGKGEQTWSHAGISKTCEIEVSQLKEQSVLEFRVFAKNEKGLSDPVT 21176

Query: 1259  ISDTIIPEVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGY----RITVVAAGEGIPIFE- 1313
             I    + E+    ++   DI  + + +R    N    + Y    + ++    +G+P+ E 
Sbjct: 21177 IGPITVKELIITPEVDLSDIPGAQVTVR-IGHNVHLELPYKGKPKPSISWLKDGLPLKES 21235

Query: 1314  DFVDSSVGYYTVT------GLEPGIDYDISVITLINGGESAPTTLTQQTAVPPPTDLRFT 1367
             +FV  S     +T        E G  Y + +   +       T +T      P   +RF 
Sbjct: 21236 EFVRFSKTENKITLSIKNAKKEHGGKYTVILDNAVCRIAVPITVITLGPPSKPKGPIRFD 21295

Query: 1368  NIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSI---SPSDNAVVLTNLLPGTE 1424
              I  D++ ++W  P   +    +  YS  K E       +   S +     + NL+   E
Sbjct: 21296 EIKADSVILSWDVPED-NGGGEITCYSIEKRETSQTNWKMVCSSVARTTFKVPNLVKDAE 21354

Query: 1425  YVVSVSSVYEQHESTPL-----RGRQKTGLDSPTGID-FSDITANSFTVHWIAP----RA 1474
             Y   V +      S PL       + +  +  P G     ++T++  ++ W AP     +
Sbjct: 21355 YQFRVRAENRYGVSQPLVSSIIVAKHQFRIPGPPGKPVIYNVTSDGMSLTWDAPVYDGGS 21414

Query: 1475  TITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQ 1534
              +TG+ +     +     + +  P S      T L  G +Y   + A N    S      
Sbjct: 21415 EVTGFHVEKKERNSILWQKVNTSPISGREYRATGLVEGLDYQFRVYAENSAGLSSPSDPS 21474

Query: 1535  QSTVS----DVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYG---ETGGNSPVQEFTV 1587
             + T++    D P   + +  T  ++ + W+ P        + Y      G    V+    
Sbjct: 21475 KFTLAVSPVDPPGTPDYIDVTRETITLKWNPPLRDGGSKIVGYSIEKRQGNERWVRCNFT 21534

Query: 1588  PGSKSTATISGLKPGVDYTITVYAVTGRGD-SPASSKPISINYRTEIDKPSQMQVTDVQD 1646
               S+   T++GL PG  Y   + A    G  SP S     I  R E   P      +  D
Sbjct: 21535 DVSECQYTVTGLSPGDRYEFRIIARNAVGTISPPSQSSGIIMTRDENVPPIVEFGPEYFD 21594

Query: 1647  -------NSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTK----TAGPDQTEMTIEGLQP 1695
                     S+ +K L    PV   RVT   K+G    K      T     T + +     
Sbjct: 21595 GLIIKSGESLRIKALVQGRPVP--RVTWF-KDGVEIEKRMNMEITDVLGSTSLFVRDATR 21651

Query: 1696  TVEYVVSVYAQNPSGESQPLVQTAVTNIDRP----KGLAFTDVDVDSIKIAWESPQGQ-- 1749
                 V +V A+N SG ++  ++  V   D P      + FT++  + + + W++P     
Sbjct: 21652 DHRGVYTVEAKNASGSAKAEIKVKVQ--DTPGKVVGPIRFTNITGEKMTLWWDAPLNDGC 21709

Query: 1750  --VSRYRVTYSSPEDGIHELFPAPDGEEDTAELQG-----LRPGSEYTVSVVALHD---- 1798
               ++ Y +           L       ED  E Q      L  G+EY   V A++     
Sbjct: 21710 APITHYIIEKRETSRLAWALI------EDKCEAQSYTAIKLINGNEYQFRVSAVNKFGVG 21763

Query: 1799  -DMESQPLIGTQSTAIP-APTDLKFTQVTPTSLSAQWTPP----NVQLTGYRVRVTPKEK 1852
               ++S P++      +P AP   + + +T  S++  W  P      ++  Y +    K+ 
Sbjct: 21764 RPLDSDPVVAQIQYTVPDAPGIPEPSNITGNSITLTWARPESDGGSEIQQYILERREKKS 21823

Query: 1853  TGPMKEINLAPDSSS-VVVSGLMVATKYEVSVYALKDTLTSRPAQGV---VTTLENVS-- 1906
             T  +K I+  P S +   V+GL    +YE  V A ++     PA G+   +   E V+  
Sbjct: 21824 TRWVKVISKRPISETRFKVTGLTEGNEYEFHVMA-ENAAGVGPASGISRLIKCREPVNPP 21882

Query: 1907  -PPRRARVTDATETTITISWRTKT----ETITGFQVDAVPANGQTPIQRTIKPDVRS-YT 1960
              PP   +VTD ++TT+++ W          I G+ ++   A+     +   +  V++ YT
Sbjct: 21883 GPPTVVKVTDTSKTTVSLEWSKPVFDGGMEIIGYIIEMCKADLGDWHKVNAEACVKTRYT 21942

Query: 1961  ITGLQPGTDYKIYLYTLN 1978
             +T LQ G +YK  +  +N
Sbjct: 21943 VTDLQAGEEYKFRVSAIN 21960



 Score =  123 bits (309), Expect = 2e-27
 Identities = 310/1432 (21%), Positives = 508/1432 (35%), Gaps = 230/1432 (16%)

Query: 814   PPDPT-VDQVDDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTLS 868
             PP P  +  V      + W+ P     +PI  Y +    +     T ++    +     +
Sbjct: 14103 PPGPVEISNVSAEKATLTWTPPLEDGGSPIKSYILEKRETSRLLWTVVSEDIQSCRHVAT 14162

Query: 869   DLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVE-VTDVKVTIMW 927
              L  G +Y   + AV    +  PV  Q E          P P +   V  VT    T+ W
Sbjct: 14163 KLIQGNEYIFRVSAVNHYGKGEPV--QSEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSW 14220

Query: 928   TPPE----SAVTGYRVDVIPV-NLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSH 982
               P     S +TGY V+     +L      + P+S +   +VTGL  G TY F+V A + 
Sbjct: 14221 KRPVDDGGSEITGYHVERREKKSLRWVRAIKTPVS-DLRCKVTGLQEGSTYEFRVSAENR 14279

Query: 983   GRESKPLTAQQTTKL-DA------PTNLQFVNETDSTVLVRWTPPR----AQITGYRLTV 1031
                  P  A  +  + DA      P+N    + T  +  + W  P      +ITGY +  
Sbjct: 14280 AGIGPPSEASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLAWGKPHYDGGLEITGYVVEH 14339

Query: 1032  GLTRRGQPRQYNVGPS--VSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGS 1089
                      +   G +  ++++ + +LQ   +Y   + AI        A      +    
Sbjct: 14340 QKVGDEAWIKDTTGTALRITQFVVPDLQTKEKYNFRISAINDAGVGEPAVIPDVEIVERE 14399

Query: 1090  SIPPY--NTEVTETTIVITWTPAPRIGFKLGVR-PSQGGEAPREVTSDSGSIVVSG---- 1142
               P +  + E+  T +V       R G  + +  P +G  AP EVT    +I +      
Sbjct: 14400 MAPDFELDAELRRTLVV-------RAGLSIRIFVPIKGRPAP-EVTWTKDNINLKNRANI 14451

Query: 1143  ---------LTPGVEYVYT---IQVLRDGQERDAPIVN-KVVTPLSPPTNLH-LEANPDT 1188
                      + P      T   +  + +   + +  VN +V+    P  NL   +   D+
Sbjct: 14452 ENTESFTLLIIPECNRYDTGKFVMTIENPAGKKSGFVNVRVLDTPGPVLNLRPTDITKDS 14511

Query: 1189  GVLTVSWERSTTPD---ITGYRITTTPTNGQQGNSLEEVVHADQSSCTFD--NLSPGLEY 1243
               +T+ W+         IT Y +       +  ++     H     CT+    LS G EY
Sbjct: 14512 --VTLHWDLPLIDGGSRITNYIVEKREATRKSYSTATTKCH----KCTYKVTGLSEGCEY 14565

Query: 1244  NVSV-----YTVKDDKESV-PISDTIIPEVPQLTDLSFVDITDSSIGLRWTPLN---SST 1294
                V     Y + +  E+  P+  +  P  P    L+ +DIT S++ L W        S 
Sbjct: 14566 FFRVMAENEYGIGEPTETTEPVKASEAPSPPD--SLNIMDITKSTVSLAWPKPKHDGGSK 14623

Query: 1295  IIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLE-------PGIDYDISVITLINGGES 1347
             I GY I     G          D      TV GLE        G +Y   V+ + + G S
Sbjct: 14624 ITGYVIEAQRKGS---------DQWTHITTVKGLECVVRNLTEGEEYTFQVMAVNSAGRS 14674

Query: 1348  APT----TLTQQTAVPPPTDLR-------FTNIGPDT---MRVTWAPPPSIDLTNFLVRY 1393
             AP      + ++  + P  DLR           G +    + V   P P++         
Sbjct: 14675 APRESRPVIVKEQTMLPELDLRGIYQKLVIAKAGDNIKVEIPVLGRPKPTVTW------- 14727

Query: 1394  SPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGL---- 1449
                K  + + + +   +      + +L   E V S S  Y      PL  R   G     
Sbjct: 14728 ---KKGDQILKQTQRVNFETTATSTILNINECVRSDSGPY------PLTARNIVGEVGDV 14778

Query: 1450  ---------DSPTG-IDFSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPRED 1495
                        PTG I F +++++  T  W  P       I+ Y +       S    E 
Sbjct: 14779 ITIQVHDIPGPPTGPIKFDEVSSDFVTFSWDPPENDGGVPISNYVVEMRQTD-STTWVEL 14837

Query: 1496  RVPHSRNSITLTNLTPGTEYVVSIVALN------GREESPLLIGQQSTVSDVPRDLEVVA 1549
                  R +   T LT G EY   + A N      G   + ++      V   P   +V A
Sbjct: 14838 ATTVIRTTYKATRLTTGLEYQFRVKAQNRYGVGPGITSACIVANYPFKVPGPPGTPQVTA 14897

Query: 1550  ATPTSLLISWDAP----AVTVRYYRITYGETGGN--SPVQEFTVPGSKSTATISGLKPGV 1603
              T  S+ ISW  P       +  Y +   E  G     V +  VPG+   +  SGL  G+
Sbjct: 14898 VTKDSMTISWHEPLSDGGSPILGYHVERKERNGILWQTVSKALVPGNIFKS--SGLTDGI 14955

Query: 1604  DYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKW----LPSSSP 1659
              Y   V A    G S  S     +     ID P +    ++  +++++KW          
Sbjct: 14956 AYEFRVIAENMAGKSKPSKPSEPMLALDPIDPPGKPVPLNITRHTVTLKWAKPEYTGGFK 15015

Query: 1660  VTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQ-- 1717
             +T Y V           K   +   + E T+ GL     Y   V A+N +G   P  +  
Sbjct: 15016 ITSYIVEKRDLPNGRWLKANFSNILENEFTVSGLTEDAAYEFRVIAKNAAGAISPPSEPS 15075

Query: 1718  TAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDT 1777
              A+T  D        DV+   IK+  +     + +    +    D      P  +  +D 
Sbjct: 15076 DAITCRD--------DVEAPKIKVDVKFKDTVILKAGEAFRLEADVSGRPPPTMEWSKDG 15127

Query: 1778  AELQGL---------------------RPGSEYTVSVVALHDDMESQPLIGTQSTAIPAP 1816
              EL+G                      R    YT++  A +    ++ +   +    P P
Sbjct: 15128 KELEGTAKLEIKIADFSTNLVNKDSTRRDSGAYTLT--ATNPGGFAKHIFNVKVLDRPGP 15185

Query: 1817  TD--LKFTQVTPTSLSAQWTPP----NVQLTGYRVRVTPKEKTGPMKEINLAPD--SSSV 1868
              +  L  T+VT       W PP      ++  Y   +  K +T  +   N+A +   + +
Sbjct: 15186 PEGPLAVTEVTSEKCVLSWFPPLDDGGAKIDHY---IVQKRETSRLAWTNVASEVQVTKL 15242

Query: 1869  VVSGLMVATKY-----EVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITI 1923
              V+ L+   +Y      V+ Y + + L S P    V       PP+   VT  T+ ++ +
Sbjct: 15243 KVTKLLKGNEYIFRVMAVNKYGVGEPLESEPVL-AVNPYGPPDPPKNPEVTTITKDSMVV 15301

Query: 1924  SW----RTKTETITGFQVDAVPANGQTPIQRTIK--PDVRSYTITGLQPGTDYKIYLYTL 1977
              W          I  + V+     GQ  I+   K   D+R Y ++GL  G +Y+  +   
Sbjct: 15302 CWGHPDSDGGSEIINYIVERRDKAGQRWIKCNKKTLTDLR-YKVSGLTEGHEYEFRIMAE 15360

Query: 1978  NDNARSSP-------VVIDASTAIDAPSNLRFLATTPNSLLVSWQPP----RARITGYII 2026
             N    S+P          D       P N R L T+ +S+ ++W  P     + ITGY++
Sbjct: 15361 NAAGISAPSPTSPFYKACDTVFKPGPPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMV 15420

Query: 2027  KYEKPGSPPREVVPRPRP-GVTEATITGLEPGTEYTIYVIALKNNQKSEPLI 2077
             +   P     ++V  P     T  TITGL    EY I + A+ +    EP +
Sbjct: 15421 EIALPEEDEWQIVTPPAGLKATSYTITGLTENQEYKIRIYAMNSEGLGEPAL 15472



 Score =  123 bits (309), Expect = 2e-27
 Identities = 338/1634 (20%), Positives = 602/1634 (36%), Gaps = 228/1634 (13%)

Query: 613   EVFITETPSQPNSHP-----------IQWNAPQ---PSHISKYILRWRPKNSVGRWKEAT 658
             E ++   P  P   P           +QW  P     S I+ YI+  R     GRW +A+
Sbjct: 17141 ECYVARDPCDPPGTPEPIMVKRNEITLQWTKPVYDGGSMITGYIVEKRDLPD-GRWMKAS 17199

Query: 659   IPGHLNS-YTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTP 717
                 + + +T+ GL     YE ++I+    G         +  S ST      +T +   
Sbjct: 17200 FTNVIETQFTVSGLTEDQRYEFRVIAKNAAGA-------ISKPSDST----GPITAKDEV 17248

Query: 718   FSPLVATSESVTEITASSFVVSWVSASD-------TVSGFRVEYELSEEGD-EPQYLDLP 769
               P ++      +    +   ++   +D       T+   R + E+ E    E +  D  
Sbjct: 17249 ELPRISMDPKFRDTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFK 17308

Query: 770   STATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPT-VDQVDDTSIV 828
             +    V     + G +YI+    ++  G +S  ++      P  P  P  V  V      
Sbjct: 17309 ALLI-VKDAIRIDGGQYILRASNVA--GSKSFPVNVKVLDRPGPPEGPVQVTGVTSEKCS 17365

Query: 829   VRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITI---- 880
             + WS P     + I+ Y +    +   + T +      NS+ ++ L  G +Y   I    
Sbjct: 17366 LTWSPPLQDGGSDISHYVVEKRETSRLAWTVVASEVVTNSLKVTKLLEGNEYVFRIMAVN 17425

Query: 881   -YAVEENQESTPVVIQQETTGTPRSDTVPSP-RDLQFVEVTDVKVTIMWTPPES----AV 934
              Y V E  ES PV+++           +P P + L+   +    +T+ W  P+S     +
Sbjct: 17426 KYGVGEPLESAPVLMKNPFV-------LPGPPKSLEVTNIAKDSMTVCWNRPDSDGGSEI 17478

Query: 935   TGYRV---DVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTA 991
              GY V   D   +     + +R+   R     VTGL+    Y F+V A +     +P  A
Sbjct: 17479 IGYIVEKRDRSGIRWIKCNKRRITDLR---LRVTGLTEDHEYEFRVSAENAAGVGEPSPA 17535

Query: 992   -------QQTTKLDAPTNLQFVNETDSTVLVRWTPP----RAQITGYRLTVGLTRRGQPR 1040
                        K   PTN   V+ T +++ + W  P     ++I GY   V + +  +  
Sbjct: 17536 TVYYKACDPVFKPGPPTNAHIVDTTKNSITLAWGKPIYDGGSEILGY--VVEICKADEEE 17593

Query: 1041  QYNVGPS----VSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNT 1096
                V P     V+++ +  L    EY + + A+       +AT V  T++P   +     
Sbjct: 17594 WQIVTPQTGLRVTRFEISKLTEHQEYKIRVCALN-KVGLGEATSVPGTVKPEDKLEAPEL 17652

Query: 1097  EVTETT---IVITWTPAPRIGFKLGVRPS-------QGGEAPREVTSDSG----SIVVSG 1142
             ++       IV+    + RI      RP+       + GE   +V  + G     + +  
Sbjct: 17653 DLDSELRKGIVVRAGGSARIHIPFKGRPTPEITWSREEGEFTDKVQIEKGVNYTQLSIDN 17712

Query: 1143  LTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHL-EANPDTGVLTVSWERSTTP 1201
                     Y +++      + A +  KV+    PP NL + E   D+  L   WE    P
Sbjct: 17713 CDRNDAGKYILKLENSSGSKSAFVTVKVLDTPGPPQNLAVKEVRKDSAFLV--WE---PP 17767

Query: 1202  DITGYRITTTPTNGQQGNSLEEVVHAD----QSSCTFDNLSPGLEYNVSVYTVKDDKESV 1257
              I G          ++ ++ +   +      ++S   +NL+ G  Y   V    +    V
Sbjct: 17768 IIDGGAKVKNYVIDKRESTRKAYANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFGVGV 17827

Query: 1258  PIS--DTIIPEVPQLTD--LSFVDITDSSIGLRWTPLN---SSTIIGYRITVVAAGEGIP 1310
             P+   D +    P      ++  D++ +S  L W        S ++GY   V    +G  
Sbjct: 17828 PVETVDAVKAAEPPSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLGY--VVEMQPKGTE 17885

Query: 1311  IFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTT---------LTQQTAVPPP 1361
              +    +S V    VTGL  G +Y   V      G+S P           LT Q ++  P
Sbjct: 17886 KWSIVAESKVCNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKLP 17945

Query: 1362  TDLRFTNIGPD---TMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTN 1418
              +      G D    + V   P P+I   +++    P+K       +++  +  + VL +
Sbjct: 17946 FNTYSIQAGEDLKIEIPVIGRPRPNI---SWVKDGEPLK---QTTRVNVEETATSTVL-H 17998

Query: 1419  LLPGTE------YVVSVSSVYEQHESTPLRGRQKTGLDSPTG-IDFSDITANSFTVHWIA 1471
             +  G +       V + +S     E+  +   +K G   P G + F +++A+   + W  
Sbjct: 17999 IKEGNKDDFGKYTVTATNSAGTATENLSVIVLEKPG--PPVGPVRFDEVSADFVVISWEP 18056

Query: 1472  PRAT----ITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREE 1527
             P  T    I+ Y +    +  +          +R +I +T L  GTEY   I A N   +
Sbjct: 18057 PAYTGGCQISNYIVEKR-DTTTTTWHMVSATVARTTIKITKLKTGTEYQFRIFAENRYGK 18115

Query: 1528  SPLLIGQQSTVS------DVPRDLEVVAATPTSLLISWDAP----AVTVRYYRITYGETG 1577
             S  L  +   V         P    V + +   +L+ W  P       +  Y +   E  
Sbjct: 18116 SAPLDSKAVIVQYPFKEPGPPGTPFVTSISKDQMLVQWHEPVNDGGTKIIGYHLEQKEKN 18175

Query: 1578  GNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPS 1637
                 V+    P   +    +GL  G++Y   V A    G    S        R   D P 
Sbjct: 18176 SILWVKLNKTPIQDTKFKTTGLDEGLEYEFKVSAENIVGIGKPSKVSECFVARDPCDPPG 18235

Query: 1638  QMQVTDVQDNSISVKW----LPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGL 1693
             + +   +  N++++KW        S +TGY V           K       +TE T+ GL
Sbjct: 18236 RPEAIVITRNNVTLKWKKPAYDGGSKITGYIVEKKDLPDGRWMKASFTNVLETEFTVSGL 18295

Query: 1694  QPTVEYVVSVYAQNPSGE-SQPLVQT-AVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVS 1751
                  Y   V A+N +G  S+P   + A+T  D        ++D  +  +  +     V 
Sbjct: 18296 VEDQRYEFRVIARNAAGNFSEPSDSSGAITARD--------EIDAPNASLDPKYKDVIVV 18347

Query: 1752  RYRVTYSSPED----GIHELFPAPDGE--EDTAELQGLRPGSEYTVSVV--ALHDD---- 1799
                 T+    D     I ++  + DG+  E+TA    ++   + T  VV   +  D    
Sbjct: 18348 HAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQY 18407

Query: 1800  -MESQPLIGTQSTAI-------PAPTD--LKFTQVTPTSLSAQWTPPNVQLTGYRVR--V 1847
              ++   + GT+S  I       P P +  LK T VT       W PP +Q  G  +   +
Sbjct: 18408 ILKLSNVGGTKSIPITVKVLDRPGPPEGPLKVTGVTAEKCYLAWNPP-LQDGGANISHYI 18466

Query: 1848  TPKEKTGPMK--EINLAPDSSSVVVSGLMVATKY-----EVSVYALKDTLTSRPAQGVVT 1900
               K +T  +   +++    + +  V+ L+   +Y      V+ Y + + L S P      
Sbjct: 18467 IEKRETSRLSWTQVSTEVQALNYKVTKLLPGNEYIFRVMAVNKYGIGEPLESGPVT-ACN 18525

Query: 1901  TLENVSPPRRARVTDATETTITISWRTKTE----TITGFQVDAVPANG--QTPIQRTIKP 1954
               +   PP    V+  T+ ++ ++W    +     I G+ ++     G   T   +    
Sbjct: 18526 PYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDKEGVRWTKCNKKTLT 18585

Query: 1955  DVRSYTITGLQPGTDYKIYLYTLNDNARSSPV-------VIDASTAIDAPSNLRFLATTP 2007
             D+R   +TGL  G  Y+  +   N      P          DA      PSN +   T+ 
Sbjct: 18586 DLR-LRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRACDALYPPGPPSNPKVTDTSR 18644

Query: 2008  NSLLVSWQPP----RARITGYIIKYEKPGSPPREVVPRPRPGV--TEATITGLEPGTEYT 2061
             +S+ ++W  P     A + GY+++  K  +        P  G+   + T+T L+  TEY 
Sbjct: 18645 SSVSLAWSKPIYDGGAPVKGYVVEV-KEAAADEWTTCTPPTGLQGKQFTVTKLKENTEYN 18703

Query: 2062  IYVIALKNNQKSEP 2075
               + A+ +    EP
Sbjct: 18704 FRICAINSEGVGEP 18717



 Score =  123 bits (309), Expect = 2e-27
 Identities = 314/1502 (20%), Positives = 546/1502 (36%), Gaps = 190/1502 (12%)

Query: 619   TPSQPNSHPIQWNAP---QPSHISKYILRWRPKNSVGRWKEATIPGHLNS--YTIKGLKP 673
             T +  +S  + W+ P     + +  Y++  + + +   W   T P  L    +T+  LK 
Sbjct: 18640 TDTSRSSVSLAWSKPIYDGGAPVKGYVVEVK-EAAADEWTTCTPPTGLQGKQFTVTKLKE 18698

Query: 674   GVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITA 733
                Y  ++ +I   G  E        T   + V    +     P   L A    V  + A
Sbjct: 18699 NTEYNFRICAINSEGVGE------PATLPGSVVAQERIE---PPEIELDADLRKVVVLRA 18749

Query: 734   SSFVVSWVSASDTVSGFRVEYELSEEGDEP-----QYLDLPSTATSVNIPDLLPGRKYIV 788
             S+ +  +V    T+ G R E E+  E  E        +++ S+ T + I ++        
Sbjct: 18750 SATLRLFV----TIKG-RPEPEVKWEKAEGILTDRAQIEVTSSFTMLVIDNVTRFDSGRY 18804

Query: 789   NVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ----APITGYRIV 844
             N+   +  G ++  ++     +P AP + T+ +V   S+ + W  P     A IT Y + 
Sbjct: 18805 NLTLENNSGSKTAFVNVRVLDSPSAPVNLTIREVKKDSVTLSWEPPLIDGGAKITNYIVE 18864

Query: 845   YSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRS 904
                +   +   +    T  +  + +LQ G  Y   + A  E     P     ETT   + 
Sbjct: 18865 KRETTRKAYATITNNCTKTTFRIENLQEGCSYYFRVLASNEYGIGLPA----ETTEPVKV 18920

Query: 905   DTVPSPRD-LQFVEVTDVKVTIMWTPPES----AVTGYRVDVIPVNLPGEHGQRLPISRN 959
                P P   +  V+VT    TI W  PES     +TGY V++       E        + 
Sbjct: 18921 SEPPLPPGRVTLVDVTRNTATIKWEKPESDGGSKITGYVVEMQTKG--SEKWSTCTQVKT 18978

Query: 960   TFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWT- 1018
               A ++GL+ G  Y F+V AV+    S P       +L  P   + +    S  L   T 
Sbjct: 18979 LEATISGLTAGEEYVFRVAAVNEKGRSDP------RQLGVPVIARDIEIKPSVELPFHTF 19032

Query: 1019  --PPRAQIT-------GYRLTVGLTRRGQP----RQYNVGPSVSKYPLRNLQPASEYTVS 1065
                 R Q+          + TV   + GQ      + NV  S +   L +++ AS+  V 
Sbjct: 19033 NVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSL-SIKEASKEDVG 19091

Query: 1066  LVAIKGNQESPKATGVFTTL---QPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPS 1122
                +  +  +   T   T +   +PG   P    EV+  +I I+W P    G   G + S
Sbjct: 19092 TYELCVSNSAGSITVPITIIVLDRPGPPGPIRIDEVSCDSITISWNPPEYDG---GCQIS 19148

Query: 1123  QGGEAPREVTSDSGSIV----------VSGLTPGVEYVYTIQVL-RDGQ----ERDAPIV 1167
                   +E TS +  IV          +  LT G EY + +    R G+    E  A + 
Sbjct: 19149 NYIVEKKETTSTTWHIVSQAVARTSIKIVRLTTGSEYQFRVCAENRYGKSSYSESSAVVA 19208

Query: 1168  NKVVTPLSPP-TNLHLEANPDTGVLTVSWERSTTPD---ITGYRITTTPTNGQQGNSLEE 1223
                 +P  PP T   + A   T  + V+W+         + GY +     +    +   +
Sbjct: 19209 EYPFSPPGPPGTPKVVHATKST--MLVTWQVPVNDGGSRVIGYHLEYKERSSILWSKANK 19266

Query: 1224  VVHADQSSCTFDNLSPGLEYNVSVYT--------VKDDKESVPISDTIIPE-VPQLTDLS 1274
             ++ AD +      L  GL Y   VY              E VP  D   P   P++T+  
Sbjct: 19267 ILIAD-TQMKVSGLDEGLMYEYRVYAENIAGIGKCSKSCEPVPARDPCDPPGQPEVTN-- 19323

Query: 1275  FVDITDSSIGLRWTPLN---SSTIIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPG 1331
                IT  S+ L+W+  +    + I GY +      +G  +  ++ +    Y+ VT L   
Sbjct: 19324 ---ITRKSVSLKWSKPHYDGGAKITGYIVERRELPDGRWLKCNYTNIQETYFEVTELTED 19380

Query: 1332  IDYDISVI------TLINGGESAPTTLTQQTAVPPPT--DLRFTNI----GPDTMRVT-- 1377
               Y+  V       ++    ES    + +    PP    D++F ++      + +++   
Sbjct: 19381 QRYEFRVFARNAADSVSEPSESTGPIIVKDDVEPPRVMMDVKFRDVIVVKAGEVLKINAD 19440

Query: 1378  --WAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNL----LPGTEYVVSVSS 1431
                 P P I      +        E+ A   I  +DN  +LT          +YV+++ +
Sbjct: 19441 IAGRPLPVISWAKDGIEI------EERARTEIISTDNHTLLTVKDCIRRDTGQYVLTLKN 19494

Query: 1432  VYEQHE-STPLRGRQKTGLDSPTG-IDFSDITANSFTVHWIAPR----ATITGYRI-RHH 1484
             V      +   +   K G   P G ++ + +TA   ++ W  P+    A I  Y + +  
Sbjct: 19495 VAGTRSVAVNCKVLDKPG--PPAGPLEINGLTAEKCSLSWGRPQEDGGADIDYYIVEKRE 19552

Query: 1485  PEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGR------EESPLLIGQQSTV 1538
               H +    E  +     S  +T L  G EY+  +  +N        E   +      TV
Sbjct: 19553 TSHLAWTICEGEL--QMTSCKVTKLLKGNEYIFRVTGVNKYGVGEPLESVAIKALDPFTV 19610

Query: 1539  SDVPRDLEVVAATPTSLLISWDAP----AVTVRYYRITYGETGGNSPVQEFTVPGSKSTA 1594
                P  LE+ + T  S+ + W  P       +  Y I   E      V+    P      
Sbjct: 19611 PSPPTSLEITSVTKESMTLCWSRPESDGGSEISGYIIERREKNSLRWVRVNKKPVYDLRV 19670

Query: 1595  TISGLKPGVDYTITVYAVTGRGDS-PASSKPISINYRTEI---DKPSQMQVTDVQDNSIS 1650
               +GL+ G +Y   VYA    G S P+ + P+ I     +     PS+ ++ D    +I+
Sbjct: 19671 KSTGLREGCEYEYRVYAENAAGLSLPSETSPL-IRAEDPVFLPSPPSKPKIVDSGKTTIT 19729

Query: 1651  VKWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQ 1706
             + W+       +P+TGY V    K+     KT       TE TI GL    EYV  V + 
Sbjct: 19730 IAWVKPLFDGGAPITGYTVEYK-KSDDTDWKTSIQSLRGTEYTISGLTTGAEYVFRVKSV 19788

Query: 1707  NPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRY---------RVTY 1757
             N  G S P   +        +     D+D +  K          +            V +
Sbjct: 19789 NKVGASDPSDSSDPQIAKEREEEPLFDIDSEMRKTLIVKAGASFTMTVPFRGRPVPNVLW 19848

Query: 1758  SSPEDGIHELFPAPDGEEDTA---ELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIP 1814
             S P+  +         +  T+   E        +YT+++  +        ++    T  P
Sbjct: 19849 SKPDTDLRTRAYVDTTDSRTSLTIENANRNDSGKYTLTIQNVLSAASLTLVVKVLDTPGP 19908

Query: 1815  APTDLKFTQVTPTSLSAQWTPP----NVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVV 1870
              PT++    VT  S    W  P       +  Y +      K   +   N   +  S  V
Sbjct: 19909 -PTNITVQDVTKESAVLSWDVPENDGGAPVKNYHIEKREASKKAWVSVTNNC-NRLSYKV 19966

Query: 1871  SGLMVATKYEVSVYALKDTLTSRPA---QGVVTTLENVSPPRRARVTDATETTITISW-- 1925
             + L     Y   V    +     PA   +GV  T E  SPP +  VT  ++ +++++W  
Sbjct: 19967 TNLQEGAIYYFRVSGENEFGVGIPAETKEGVKIT-EKPSPPEKLGVTSISKDSVSLTWLK 20025

Query: 1926  --RTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARS 1983
                     I  + V+A+    +  ++  +      + ++GL+  ++Y   ++  N    S
Sbjct: 20026 PEHDGGSRIVHYVVEALEKGQKNWVKCAVAKSTH-HVVSGLRENSEYFFRVFAENQAGLS 20084

Query: 1984  SP 1985
              P
Sbjct: 20085 DP 20086



 Score =  122 bits (307), Expect = 3e-27
 Identities = 331/1598 (20%), Positives = 562/1598 (35%), Gaps = 189/1598 (11%)

Query: 624   NSHPIQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNS--YTIKGLKPGVVYE 678
             NS  + W  P+    S I +YIL  R K S  RW +      ++   + + GL  G  YE
Sbjct: 21794 NSITLTWARPESDGGSEIQQYILERREKKST-RWVKVISKRPISETRFKVTGLTEGNEYE 21852

Query: 679   GQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVV 738
               +++    G    +           PV          P  P V     VT+ + ++  +
Sbjct: 21853 FHVMAENAAGVGPASGIS-RLIKCREPVNP--------PGPPTVV---KVTDTSKTTVSL 21900

Query: 739   SW----VSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQIS 794
              W          + G+ +E   ++ GD  +        T   + DL  G +Y   V  I+
Sbjct: 21901 EWSKPVFDGGMEIIGYIIEMCKADLGDWHKVNAEACVKTRYTVTDLQAGEEYKFRVSAIN 21960

Query: 795   EDGEQSLILSTSQTTAPD--APPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGS 852
               G+      T    A D    P+  +D     + VVR          Y+   +P+   S
Sbjct: 21961 GAGKGDSCEVTGTIKAVDRLTAPELDIDANFKQTHVVRAGASIRLFIAYQGRPTPTAVWS 22020

Query: 853   STELNLPETANSVTLSDLQPGVQYNIT-------IYAVEENQESTPVVIQQETTGTPRSD 905
               + NL   A+  T          N            VE N  S  +    +   TP   
Sbjct: 22021 KPDSNLSLRADIHTTDSFSTLTVENCNRNDAGKYTLTVENNSGSKSITFTVKVLDTPGP- 22079

Query: 906   TVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPGEHGQRLPISRNTF 961
                 P  + F +VT    T+MW  P     + +  Y V+    +           +R  F
Sbjct: 22080 ----PGPITFKDVTRGSATLMWDAPLLDGGARIHHYVVEKREASRRSWQVISEKCTRQIF 22135

Query: 962   AEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQ----TTKLDAPTNLQFVNETDSTVLVRW 1017
              +V  L+ GV YYF+V AV+     +P    +    T +   P  L  V+ + S+ ++ W
Sbjct: 22136 -KVNDLAEGVPYYFRVSAVNEYGVGEPYEMPEPIVATEQPAPPRRLDVVDTSKSSAVLAW 22194

Query: 1018  TPP----RAQITGYRLTVGLTRRGQPRQYNVGPSVS-KYPLRNLQPASEY---------- 1062
               P     ++ITGY L   + ++G       G +    + +  L   +EY          
Sbjct: 22195 LKPDHDGGSRITGYLLE--MRQKGSDFWVEAGHTKQLTFTVERLVEKTEYEFRVKAKNDA 22252

Query: 1063  -------TVSLVAIKGNQESPKA--TGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRI 1113
                      S V IK  Q  P A  TG+   L    +  P+  +V      I+  PAP++
Sbjct: 22253 GYSEPREAFSSVIIKEPQIEPTADLTGITNQLITCKAGSPFTIDVP-----ISGRPAPKV 22307

Query: 1114  GFKL-GVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVT 1172
              +KL  +R  +        T D  ++ V     G    Y + +      +   +   V+ 
Sbjct: 22308 TWKLEEMRLKETDRVSITTTKDRTTLTVKDSMRGDSGRYFLTLENTAGVKTFSVTVVVIG 22367

Query: 1173  PLSPPTNLHLEANPDTGVLTVSW---ERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQ 1229
                P T     ++       +SW   +     +IT Y +    +       +   V   Q
Sbjct: 22368 RPGPVTGPIEVSSVSAESCVLSWGEPKDGGGTEITNYIVEKRESGTTAWQLVNSSVKRTQ 22427

Query: 1230  SSCTFDNLSPGLEYNVSV-----YTVKDDKESVPI---SDTIIPEVPQLTDLSFVDITDS 1281
                T  +L+  +EY+  V     + V    ES PI      + P  P  T      ++ +
Sbjct: 22428 IKVT--HLTKYMEYSFRVSSENRFGVSKPLESAPIIAEHPFVPPSAP--TRPEVYHVSAN 22483

Query: 1282  SIGLRWTPL---NSSTIIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISV 1338
             ++ +RW        S IIGY +        + + E+ V      Y VTGL  G++Y    
Sbjct: 22484 AMSIRWEEPYHDGGSKIIGYWVEKKERNTILWVKENKVPCLECNYKVTGLVEGLEYQFRT 22543

Query: 1339  ITLINGGES----APTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAPPP---SIDLTNFLV 1391
               L   G S    A   +  Q  V  P     T++   T+ + W+ P       +  +++
Sbjct: 22544 YALNAAGVSKASEASRPIMAQNPVDAPGRPEVTDVTRSTVSLIWSAPAYDGGSKVVGYII 22603

Query: 1392  RYSPVKNEEDVAELSIS---PSDNAVVLTNLLPGTEYVVSVSS------VYEQHEST-PL 1441
                PV    D   L  +    SDN   +T L  G  Y   V +      + +  EST P+
Sbjct: 22604 ERKPVSEVGDGRWLKCNYTIVSDNFFTVTALSEGDTYEFRVLAKNAAGVISKGSESTGPV 22663

Query: 1442  RGRQ-----KTGLDSPTGIDFSDITANSFTVHWIA----PRATITGYRIRHHPEHFSGRP 1492
               R      K  LD+    D   I A S  V   A    P   I   +     +      
Sbjct: 22664 TCRDEYAPPKAELDARLHGDLVTIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVS 22723

Query: 1493  REDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVP---RDLEVVA 1549
              +     +   I   + +   +Y +++   +G +   +++     V D P     L V  
Sbjct: 22724 LQYTGKRATAVIKFCDRSDSGKYTLTVKNASGTKAVSVMV----KVLDSPGPCGKLTVSR 22779

Query: 1550  ATPTSLLISWDAP----AVTVRYYRITYGETGGNSPVQEFTVPGSKSTAT--ISGLKPGV 1603
              T     ++W  P       + +Y +   ET   S +    V G   T +  ++ L    
Sbjct: 22780 VTQEKCTLAWSLPQEDGGAEITHYIVERRET---SRLNWVIVEGECPTLSYVVTRLIKNN 22836

Query: 1604  DYTITVYAVTGRGDS-PASSKPI-SINYRTEIDKPSQMQVTDVQDNSISVKWLPSSS--- 1658
             +Y   V AV   G   P  S+PI + N  T    P   +        I ++W    S   
Sbjct: 22837 EYIFRVRAVNKYGPGVPVESEPIVARNSFTIPSPPGIPEEVGTGKEHIIIQWTKPESDGG 22896

Query: 1659  -PVTGYRVTTTPKNGPGPTK-TKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLV 1716
               ++ Y V    K     T+  K      T + +  L    +Y   V A N +G S+P  
Sbjct: 22897 NEISNYLVDKREKKSLRWTRVNKDYVVYDTRLKVTSLMEGCDYQFRVTAVNAAGNSEPSE 22956

Query: 1717  QTAVTNIDR-------PKGLAFTDVDVDSIKIAWESPQGQVSRYRVTY-----SSPEDGI 1764
              +   +          P      D    SI +AW  P        V Y         D  
Sbjct: 22957 ASNFISCREPSYTPGPPSAPRVVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDTDQW 23016

Query: 1765  HELFPAPDGEEDTAELQGLRPGSEYTVSVVALH---------DDMESQPLIGTQSTAIPA 1815
             + +            +  L+ G +Y+  V A++            E +P+   +   +  
Sbjct: 23017 YRVHTNATIRNTEFTVPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEIPDLEL 23076

Query: 1816  PTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTG---PMKEINLAPDSSSVVVSG 1872
               DLK T       S +     V ++G    V    K G     + I    +S S+++  
Sbjct: 23077 ADDLKKTVTIRAGASLRLM---VSVSGRPPPVITWSKQGIDLASRAIIDTTESYSLLI-- 23131

Query: 1873  LMVATKYEVSVYALKDTLTS--RPAQGVVTTLENVSPPRRARVTDATETTITISWRTKT- 1929
             +    +Y+   Y ++    S  + A  +V   +   P    +V + +  ++TI+W   T 
Sbjct: 23132 VDKVNRYDAGKYTIEAENQSGKKSATVLVKVYDTPGPCPSVKVKEVSRDSVTITWEIPTI 23191

Query: 1930  ---ETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKI-----YLYTLNDNA 1981
                  +  + V+   A  +     T K     Y I+GL  GT Y        +Y + +  
Sbjct: 23192 DGGAPVNNYIVEKREAAMRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYGIGEPC 23251

Query: 1982  RSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPP----RARITGYIIKYEKPGSPPRE 2037
              +S  V+ +   +  P+ L  +  T +++ ++W+ P     +R+TGY+++  K G+    
Sbjct: 23252 ETSDAVLVSEVPL-VPAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGTERWM 23310

Query: 2038  VVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEP 2075
              V   +P V E T+T L  G +Y   + A      SEP
Sbjct: 23311 KVVTLKPTVLEHTVTSLNEGEQYLFRIRAQNEKGVSEP 23348



 Score =  120 bits (301), Expect = 2e-26
 Identities = 286/1368 (20%), Positives = 511/1368 (37%), Gaps = 206/1368 (15%)

Query: 866   TLSDLQPGVQYNITIYAVEENQEST-PVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVT 924
             T++ L  G +Y   + A  EN+  T P    +      + D    P   +  +V+  ++T
Sbjct: 11984 TVTRLIEGNEYIFRVRA--ENKIGTGPPTESKPVIAKTKYDKPGRPDPPEVTKVSKEEMT 12041

Query: 925   IMWTPPE----SAVTGYRVDVIPVNLPGEHGQR-LPISRNTFAE----VTGLSPGVTYYF 975
             ++W PPE     ++TGY ++        +H  R +P++++   E    V  L P   Y F
Sbjct: 12042 VVWNPPEYDGGKSITGYFLEK-----KEKHSTRWVPVNKSAIPERRMKVQNLLPDHEYQF 12096

Query: 976   KVFAVSH------GRESKPLTAQQTTKLDAP-TNLQFVNETDSTVLVRWTPP----RAQI 1024
             +V A +          S+P+ A+   +   P TN + V+ T  ++ + W  P     A I
Sbjct: 12097 RVKAENEIGIGEPSLPSRPVVAKDPIEPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAPI 12156

Query: 1025  TGY------RLTVGLTRRGQPRQYNVGPSVSK-YPLRNLQPASEYTVSL-----VAIKGN 1072
              GY      ++       G  R       V K + + +L    EY   +     V I   
Sbjct: 12157 IGYVVEMRPKIADASPDEGWKRCNAAAQLVRKEFTVTSLDENQEYEFRVCAQNQVGIGRP 12216

Query: 1073  QESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWT-------------PAPRIGFKLGV 1119
              E  +A      L+P    P  + + +   +VI                PAP++ ++   
Sbjct: 12217 AELKEAIKPKEILEP----PEIDLDASMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVG 12272

Query: 1120  RPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTN 1179
               +   +   ++      +V+   T      Y++ ++    E+   +  +V+    P ++
Sbjct: 12273 IDNVVRKGQVDLVDTMAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFVNVRVLDTPGPVSD 12332

Query: 1180  LHLEANPDTGVLTVSW---ERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDN 1236
             L +     T    VSW   E      +T Y +     + +  +++   V   ++S    N
Sbjct: 12333 LKVSDVTKTSC-HVSWAPPENDGGSQVTHYIVEKREADRKTWSTVTPEVK--KTSFHVTN 12389

Query: 1237  LSPGLEYNVSVYTVKDDKESVPI--------SDTII-PEVPQLTDLSFVDITDSSIGLRW 1287
             L PG EY   V  V +    VP         SD +  P+ P+   L   ++T +S  L W
Sbjct: 12390 LVPGNEYYFRVTAVNEYGPGVPTDVPKPVLASDPLSEPDPPR--KLEVTEMTKNSATLAW 12447

Query: 1288  TPL---NSSTIIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLING 1344
              P      + I GY  +     +    + ++         VTGL+ G  Y   V      
Sbjct: 12448 LPPLRDGGAKIDGYITSYREEEQPADRWTEYSVVKDLSLVVTGLKEGKKYKFRVAARNAV 12507

Query: 1345  GESAPTTL-----TQQTAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVK-- 1397
             G S P         ++  +PP        + P+ + +       I+   +   +   K  
Sbjct: 12508 GVSLPREAEGVYEAKEQLLPPKI------LMPEQITIKAGKKLRIEAHVYGKPHPTCKWK 12561

Query: 1398  -NEEDV---AELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSP- 1452
               E++V   + L++  +D++ +L       +     S   E    T  +  +   +D+P 
Sbjct: 12562 KGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPG 12621

Query: 1453  ---TGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPH----SRNSIT 1505
                   D SDI A++ ++ W  P     G  I ++        R D V      ++ S  
Sbjct: 12622 PPQPPFDISDIDADACSLSWHIPLED-GGSNITNYIVEKCDVSRGDWVTALASVTKTSCR 12680

Query: 1506  LTNLTPGTEYVVSIVALN--GREE---SPLLIGQ-QSTVSDVPRDLEVVAATPTSLLISW 1559
             +  L PG EY+  + A N  G  E   SP ++ Q    V   P++  V       + ++W
Sbjct: 12681 VGKLIPGQEYIFRVRAENRFGISEPLTSPKMVAQFPFGVPSEPKNARVTKVNKDCIFVAW 12740

Query: 1560  DAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATI----------------SGLKPGV 1603
             D P            ++ G SP+  + +   +  + +                +GL  G+
Sbjct: 12741 DRP------------DSDGGSPIIGYLIERKERNSLLWVKANDTLVRSTEYPCAGLVEGL 12788

Query: 1604  DYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWL----PSSSP 1659
             +Y+  +YA+   G SP S     +  R  +D P + +V DV  +++S+ W        S 
Sbjct: 12789 EYSFRIYALNKAGSSPPSKPTEYVTARMPVDPPGKPEVIDVTKSTVSLIWARPKHDGGSK 12848

Query: 1660  VTGYRVTTTPKNGPGPTKTKTAGPD--QTEMTIEGLQPTVEYVVSVYAQN------PSGE 1711
             + GY V      G    +  TA     Q E T  GL+   +Y     A+       PS  
Sbjct: 12849 IIGYFVEACKLPGDKWVRCNTAPHQIPQEEYTATGLEEKAQYQFRAIARTAVNISPPSEP 12908

Query: 1712  SQP---LVQTAVTNIDRPKGL-------AFTDVDVDSIKIAWESPQGQVS-RYRVTYSSP 1760
             S P   L +     ID    +       A T+V +D+    +  P   VS +   T   P
Sbjct: 12909 SDPVTILAENVPPRIDLSVAMKSLLTVKAGTNVCLDA--TVFGKPMPTVSWKKDGTLLKP 12966

Query: 1761  EDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPA-PTDL 1819
              +GI     A      T EL  +        ++ A +        I  +    P  P  +
Sbjct: 12967 AEGIK---MAMQRNLCTLELFSVNRKDSGDYTITAENSSGSKSATIKLKVLDKPGPPASV 13023

Query: 1820  KFTQVTPTSLSAQWTPP----NVQLTGYRVRVTPKEKTGP-MKEINLAPDSSSVVVSGLM 1874
             K  ++        W PP      ++T Y   V  +E + P   +++     +S  V  L+
Sbjct: 13024 KINKMYSDRAMLSWEPPLEDGGSEITNY--IVDKRETSRPNWAQVSATVPITSCSVEKLI 13081

Query: 1875  VATKYEVSV-----YALKDTLTSRPAQGVVTTLENVSPPRRAR---VTDATETTITISWR 1926
                +Y+  +     Y + D + + PA           PP R     +++ T+  +T+SW+
Sbjct: 13082 EGHEYQFRICAENKYGVGDPVFTEPA----IAKNPYDPPGRCDPPVISNITKDHMTVSWK 13137

Query: 1927  TKTE----TITGFQVDAVPANGQTPIQRTIKPDV-RSYTITGLQPGTDYKIYLYTLNDNA 1981
                +     ITG+ ++          +   KP + R+   TGLQ GT+Y+  +  +N   
Sbjct: 13138 PPADDGGSPITGYLLEKRETQAVNWTKVNRKPIIERTLKATGLQEGTEYEFRVTAINKAG 13197

Query: 1982  RSSPVVIDASTAIDA---------PSNLRFLATTPNSLLVSWQPPR----ARITGYIIKY 2028
                P   DAS A  A         P+  +   TT +S+ +SW  P     + I GY+++ 
Sbjct: 13198 PGKP--SDASKAAYARDPQYPPGPPAFPKVYDTTRSSVSLSWGKPAYDGGSPIIGYLVEV 13255

Query: 2029  EKPGSPPREVVPRPRP-GVTEATITGLEPGTEYTIYVIALKNNQKSEP 2075
             ++  S        P+    T   +TGL   T+Y   V A+     S+P
Sbjct: 13256 KRADSDNWVRCNLPQNLQKTRFEVTGLMEDTQYQFRVYAVNKIGYSDP 13303



 Score =  120 bits (301), Expect = 2e-26
 Identities = 304/1512 (20%), Positives = 534/1512 (35%), Gaps = 204/1512 (13%)

Query: 718   FSPLVATSESVTEITASSFVVSW----VSASDTVSGFRVEYELSEEGDEPQYLDLPSTA- 772
             F P   T+  + + T +S  ++W          + G+ VE  + +  +E   +  P T  
Sbjct: 17546 FKPGPPTNAHIVDTTKNSITLAWGKPIYDGGSEILGYVVE--ICKADEEEWQIVTPQTGL 17603

Query: 773   --TSVNIPDLLPGRKYIVNVYQISEDG--EQSLILSTSQTTAPDAPPDPTVDQVDDTSIV 828
               T   I  L   ++Y + V  +++ G  E + +  T +       P+  +D      IV
Sbjct: 17604 RVTRFEISKLTEHQEYKIRVCALNKVGLGEATSVPGTVKPEDKLEAPELDLDSELRKGIV 17663

Query: 829   VRW---SRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYN-ITIYAVE 884
             VR    +R   P  G     +P +  S  E    +         ++ GV Y  ++I   +
Sbjct: 17664 VRAGGSARIHIPFKGRP---TPEITWSREEGEFTDKVQ------IEKGVNYTQLSIDNCD 17714

Query: 885   ENQESTPVVIQQETTGTPRS-------DTVPSPRDLQFVEVTDVKVTIMWTPP----ESA 933
              N     ++  + ++G+  +       DT   P++L   EV      ++W PP     + 
Sbjct: 17715 RNDAGKYILKLENSSGSKSAFVTVKVLDTPGPPQNLAVKEVRKDSAFLVWEPPIIDGGAK 17774

Query: 934   VTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQ 993
             V  Y +D                S+ +F +V  L+ G  YYF+V A +      P+    
Sbjct: 17775 VKNYVIDKRESTRKAYANVSSKCSKTSF-KVENLTEGAIYYFRVMAENEFGVGVPVETVD 17833

Query: 994   TTKLDAPTN------LQFVNETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYN 1043
               K   P +      L  V++T ++++  W  P     +++ GY   V +  +G  +   
Sbjct: 17834 AVKAAEPPSPPGKVTLTDVSQTSASLM--WEKPEHDGGSRVLGY--VVEMQPKGTEKWSI 17889

Query: 1044  VGPS-VSKYPLRNLQPASEYTVSLVAIKGNQES-PKATGVFT-----TLQPGSSIPPYNT 1096
             V  S V    +  L    EY   + A     +S P+  GV       T+QP   +P +NT
Sbjct: 17890 VAESKVCNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKLP-FNT 17948

Query: 1097  ------EVTETTIVITWTPAPRIGF-KLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEY 1149
                   E  +  I +   P P I + K G    Q      E T+ S  + +         
Sbjct: 17949 YSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFG 18008

Query: 1150  VYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTP---DITGY 1206
              YT+            +   V+    PP             + +SWE         I+ Y
Sbjct: 18009 KYTVTATNSAGTATENLSVIVLEKPGPPVGPVRFDEVSADFVVISWEPPAYTGGCQISNY 18068

Query: 1207  RITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTII-- 1264
              +    T     + +   V   +++     L  G EY   ++      +S P+    +  
Sbjct: 18069 IVEKRDTTTTTWHMVSATVA--RTTIKITKLKTGTEYQFRIFAENRYGKSAPLDSKAVIV 18126

Query: 1265  ---------PEVPQLTDLSFVDITDSSIGLRW-TPLNS--STIIGYRITVVAAGEGIPIF 1312
                      P  P +T +S        + ++W  P+N   + IIGY +        + + 
Sbjct: 18127 QYPFKEPGPPGTPFVTSIS-----KDQMLVQWHEPVNDGGTKIIGYHLEQKEKNSILWVK 18181

Query: 1313  EDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQ----QTAVPPPTDLRFTN 1368
              +        +  TGL+ G++Y+  V      G   P+ +++    +    PP       
Sbjct: 18182 LNKTPIQDTKFKTTGLDEGLEYEFKVSAENIVGIGKPSKVSECFVARDPCDPPGRPEAIV 18241

Query: 1369  IGPDTMRVTWAPPP---SIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEY 1425
             I  + + + W  P       +T ++V     K+  D   +  S        TN+L  TE+
Sbjct: 18242 ITRNNVTLKWKKPAYDGGSKITGYIVEK---KDLPDGRWMKAS-------FTNVLE-TEF 18290

Query: 1426  VVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITG-YR---I 1481
              VS   V +Q     +  R   G  S        ITA        AP A++   Y+   +
Sbjct: 18291 TVS-GLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARD---EIDAPNASLDPKYKDVIV 18346

Query: 1482  RHHPEHF------SGRPREDRV--------------PHSRNSITLTNL-------TPGTE 1514
              H  E F       G+P  D V                 +++I  T L       T G +
Sbjct: 18347 VHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQ 18406

Query: 1515  YVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAP----AVTVRYYR 1570
             Y++ +  + G +  P+ +            L+V   T     ++W+ P       + +Y 
Sbjct: 18407 YILKLSNVGGTKSIPITVKVLDRPGPPEGPLKVTGVTAEKCYLAWNPPLQDGGANISHYI 18466

Query: 1571  ITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRG-DSPASSKPISI-N 1628
             I   ET   S  Q  T   + +   ++ L PG +Y   V AV   G   P  S P++  N
Sbjct: 18467 IEKRETSRLSWTQVSTEVQALNYK-VTKLLPGNEYIFRVMAVNKYGIGEPLESGPVTACN 18525

Query: 1629  YRTEIDKPSQMQVTDVQDNSISVKWL----PSSSPVTGYRVTTTPKNGPGPTKTKTAGPD 1684
                    PS  +V+ +  +S+ V W        + + GY +    K G   TK       
Sbjct: 18526 PYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDKEGVRWTKCNKKTLT 18585

Query: 1685  QTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQT-------AVTNIDRPKGLAFTDVDVD 1737
                + + GL     Y   V A+N +G  +P   +       A+     P     TD    
Sbjct: 18586 DLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRACDALYPPGPPSNPKVTDTSRS 18645

Query: 1738  SIKIAWESP----QGQVSRYRVTYSSPEDGIHELFPAPDGEEDTA-ELQGLRPGSEYTVS 1792
             S+ +AW  P       V  Y V               P G +     +  L+  +EY   
Sbjct: 18646 SVSLAWSKPIYDGGAPVKGYVVEVKEAAADEWTTCTPPTGLQGKQFTVTKLKENTEYNFR 18705

Query: 1793  VVALHDDMESQPL-----IGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRV 1847
             + A++ +   +P      +  Q    P   +L         L A  T         R+ V
Sbjct: 18706 ICAINSEGVGEPATLPGSVVAQERIEPPEIELDADLRKVVVLRASAT--------LRLFV 18757

Query: 1848  TPKEKTGPM----KEINLAPDSSSVVVSGLMV------ATKYEVSVY--ALKDTLTSRPA 1895
             T K +  P     K   +  D + + V+           T+++   Y   L++   S+ A
Sbjct: 18758 TIKGRPEPEVKWEKAEGILTDRAQIEVTSSFTMLVIDNVTRFDSGRYNLTLENNSGSKTA 18817

Query: 1896  QGVVTTLENVSPPRRARVTDATETTITISWRTKT----ETITGFQVDAVPANGQTPIQRT 1951
                V  L++ S P    + +  + ++T+SW          IT + V+      +     T
Sbjct: 18818 FVNVRVLDSPSAPVNLTIREVKKDSVTLSWEPPLIDGGAKITNYIVEKRETTRKAYATIT 18877

Query: 1952  IKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAP----SNLRFLATTP 2007
                   ++ I  LQ G  Y   +   N+     P        +  P      +  +  T 
Sbjct: 18878 NNCTKTTFRIENLQEGCSYYFRVLASNEYGIGLPAETTEPVKVSEPPLPPGRVTLVDVTR 18937

Query: 2008  NSLLVSWQPPRA----RITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIY 2063
             N+  + W+ P +    +ITGY+++ +  GS       + +    EATI+GL  G EY   
Sbjct: 18938 NTATIKWEKPESDGGSKITGYVVEMQTKGSEKWSTCTQVK--TLEATISGLTAGEEYVFR 18995

Query: 2064  VIALKNNQKSEP 2075
             V A+    +S+P
Sbjct: 18996 VAAVNEKGRSDP 19007



 Score =  119 bits (298), Expect = 4e-26
 Identities = 329/1550 (21%), Positives = 553/1550 (35%), Gaps = 222/1550 (14%)

Query: 601   PLQTYPSSSGPVEVFITETPSQPN-------SHPIQWNAPQ---PSHISKYILRWRPKNS 650
             P +T P       VF+   PS+P        +  I W  P     + I+ Y + ++  + 
Sbjct: 19696 PSETSPLIRAEDPVFLPSPPSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEYKKSDD 19755

Query: 651   VGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNT 710
                WK +        YTI GL  G  Y  ++ S+ + G  +        + +S P  +  
Sbjct: 19756 TD-WKTSIQSLRGTEYTISGLTTGAEYVFRVKSVNKVGASD-------PSDSSDPQIAKE 19807

Query: 711   VTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVS--GFRVEYELSEEGDEP----Q 764
                E     PL       +E+  +  V +  S + TV   G  V   L  + D       
Sbjct: 19808 REEE-----PLFDID---SEMRKTLIVKAGASFTMTVPFRGRPVPNVLWSKPDTDLRTRA 19859

Query: 765   YLDLPSTATSVNIPDLL--PGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQV 822
             Y+D   + TS+ I +       KY + +  +      +L++    T  P  P + TV  V
Sbjct: 19860 YVDTTDSRTSLTIENANRNDSGKYTLTIQNVLSAASLTLVVKVLDTPGP--PTNITVQDV 19917

Query: 823   DDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNI 878
                S V+ W  P+    AP+  Y I    + + +   +       S  +++LQ G  Y  
Sbjct: 19918 TKESAVLSWDVPENDGGAPVKNYHIEKREASKKAWVSVTNNCNRLSYKVTNLQEGAIYYF 19977

Query: 879   TIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAV 934
              +    E     P   ++   G   ++    P  L    ++   V++ W  PE    S +
Sbjct: 19978 RVSGENEFGVGIPAETKE---GVKITEKPSPPEKLGVTSISKDSVSLTWLKPEHDGGSRI 20034

Query: 935   TGYRVDVIPVNLPGEHGQR----LPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKP-- 988
               Y V+ +      E GQ+      ++++T   V+GL     Y+F+VFA +    S P  
Sbjct: 20035 VHYVVEAL------EKGQKNWVKCAVAKSTHHVVSGLRENSEYFFRVFAENQAGLSDPRE 20088

Query: 989   -LTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPS 1047
              L      +   P  +   N    TV VR         G  L V +   G+P    V  S
Sbjct: 20089 LLLPVLIKEQLEPPEIDMKNFPSHTVYVR--------AGSNLKVDIPISGKPLP-KVTLS 20139

Query: 1048  VSKYPLR-NLQPASEYTV---------SLVAIKGNQESPKATGVFTTL---------QPG 1088
                 PL+  ++  +E T          S+ A  G  E   A    TT          +PG
Sbjct: 20140 RDGVPLKATMRFNTEITAENLTINLKESVTADAGRYEITAANSSGTTKAFINIVVLDRPG 20199

Query: 1089  SSI-PPYNTEVTETTIVITWTPAPRIG-------FKLGVRPSQGGEAPREVTSDSGSIVV 1140
                 P   +++TE ++ + W P    G         L    S         T     + V
Sbjct: 20200 PPTGPVVISDITEESVTLKWEPPKYDGGSQVTNYILLKRETSTAVWTEVSATVARTMMKV 20259

Query: 1141  SGLTPGVEYVYTIQV-----LRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSW 1195
               LT G EY + I+      + D  +     V    T   PP+   +  N     +TV W
Sbjct: 20260 MKLTTGEEYQFRIKAENRFGISDHIDSACVTVKLPYTTPGPPSTPWV-TNVTRESITVGW 20318

Query: 1196  ERSTT---PDITGYRITTTPTNG---QQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYT 1249
                 +     + GY +     N    Q+ N L  V+       T   +S GL Y   VY 
Sbjct: 20319 HEPVSNGGSAVVGYHLEMKDRNSILWQKANKL--VIRTTHFKVT--TISAGLIYEFRVYA 20374

Query: 1250  V------KDDKESVPISDTIIPEVPQLTDLSFVDITDSSIGLRWTPL---NSSTIIGYRI 1300
                    K    S P+      E P+  ++   DI+ +S+ L W        S I GY +
Sbjct: 20375 ENAAGVGKPSHPSEPVLAIDACEPPR--NVRITDISKNSVSLSWQQPAFDGGSKITGYIV 20432

Query: 1301  TVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISV------------------ITLI 1342
                   +G      F + +   + ++GL     Y+  V                  IT I
Sbjct: 20433 ERRDLPDGRWTKASFTNVTETQFIISGLTQNSQYEFRVFARNAVGSISNPSEVVGPITCI 20492

Query: 1343  N--GGE--SAPTTLTQQTAVPPPTD--LRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPV 1396
             +  GG     P   T+       T   LR    G     + W        TN LV    V
Sbjct: 20493 DSYGGPVIDLPLEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALV---CV 20549

Query: 1397  KNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTG-I 1455
             +N  D+A + I  +D        L    Y + + +      +T +R +       P G I
Sbjct: 20550 ENTTDLASILIKDADR-------LNSGCYELKLRNAMGSASAT-IRVQILDKPGPPGGPI 20601

Query: 1456  DFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNS-------ITLTN 1508
             +F  +TA   T+ W  P A   G +I H   +   +    RV  S  S       IT T 
Sbjct: 20602 EFKTVTAEKITLLW-RPPADDGGAKITH---YIVEKRETSRVVWSMVSEHLEECIITTTK 20657

Query: 1509  LTPGTEYVVSIVALNGRE-----ESPLLIGQQSTVSDVPRDL-EVVAATPTSLLISWDAP 1562
             +  G EY+  + A+N        ES  ++ + + V+  P  + EV   T  S+ + W  P
Sbjct: 20658 IIKGNEYIFRVRAVNKYGIGEPLESDSVVAKNAFVTPGPPGIPEVTKITKNSMTVVWSRP 20717

Query: 1563  A------VTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRG 1616
                    ++  +      ++ G   V + T+  ++   T  GL    DY   V AV   G
Sbjct: 20718 IADGGSDISGYFLEKRDKKSLGWFKVLKETIRDTRQKVT--GLTENSDYQYRVCAVNAAG 20775

Query: 1617  DSPASSKPISINYRTEID---KPSQMQVTDVQDNSISVKW----LPSSSPVTGYRVTTTP 1669
               P S           ID    P+++++ D   +SI++ W        S VTGY V    
Sbjct: 20776 QGPFSEPSEFYKAADPIDPPGPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVVEIRQ 20835

Query: 1670  KNGPGPTKTKTAGPDQ-TEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKG 1728
                   T   T G  + TE  +  L+P V Y   V A N +G+ +P+       +     
Sbjct: 20836 GEEEEWTTVSTKGEVRTTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMN--EPVQAKDI 20893

Query: 1729  LAFTDVDVD-SIKIAWESPQGQVSRYRVTYSS--PEDGIHELFPAPDGEEDTAELQGLRP 1785
             L   ++D+D +++ +  +  G+  +  + +    P            G +    ++    
Sbjct: 20894 LEAPEIDLDVALRTSVIAKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYSIENTDS 20953

Query: 1786  GSEYTVSVVALHDDME---------SQPLIGTQSTAI----PAPTDLKFTQVTPTSLSAQ 1832
              S  T+  V  +D  +          +P   T S  +     A   L+   V+  +++  
Sbjct: 20954 SSLLTIPQVTRNDTGKYILTIENGVGEPKSSTVSVKVLDTPAACQKLQVKHVSRGTVTLL 21013

Query: 1833  WTPPNVQLTGYRVRVTPKEKTGPMKEINLAP---DSSSVVVSGLMVATKYEVSVYALKDT 1889
             W PP +      +    +++    +  ++      S+S  +  L   T +   V A  + 
Sbjct: 21014 WDPPLIDGGSPIINYVIEKRDATKRTWSVVSHKCSSTSFKLIDLSEKTPFFFRVLAENEI 21073

Query: 1890  LTSRPAQGV--VTTLENVSPPRRARVTDATETTITISWRTKTE-----TITGFQVDAVPA 1942
                 P +    V   E  +P R   + D+T+T++ +SW TK +      IT + V+    
Sbjct: 21074 GIGEPCETTEPVKAAEVPAPIRDLSMKDSTKTSVILSW-TKPDFDGGSVITEYVVERKGK 21132

Query: 1943  NGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDAST 1992
               QT     I        ++ L+  +  +  ++  N+   S PV I   T
Sbjct: 21133 GEQTWSHAGISKTC-EIEVSQLKEQSVLEFRVFAKNEKGLSDPVTIGPIT 21181



 Score =  118 bits (296), Expect = 6e-26
 Identities = 330/1625 (20%), Positives = 588/1625 (36%), Gaps = 230/1625 (14%)

Query: 611   PVEVFITETPSQPNSHPIQWNAP---QPSHISKYILRWRPKNSVGRWKEATIPGHLNSYT 667
             PV V + E     +S  + W  P     S I  Y+++ R       W   T      S+ 
Sbjct: 13418 PVNVTVKEISK--DSAYVTWEPPIIDGGSPIINYVVQKRDAERKS-WSTVTTECSKTSFR 13474

Query: 668   IKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSES 727
             +  L+ G  Y  ++ +  +YG  +               T + V    TP  P+V     
Sbjct: 13475 VANLEEGKSYFFRVFAENEYGIGDPGE------------TRDAVKASQTP-GPVVDLK-- 13519

Query: 728   VTEITASSFVVSWVS----ASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPG 783
             V  ++ SS  + W          + G+ V++ L+EE    + +   S +   +  DL  G
Sbjct: 13520 VRSVSKSSCSIGWKKPHSDGGSRIIGYVVDF-LTEENKWQRVMK--SLSLQYSAKDLTEG 13576

Query: 784   RKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWS---RPQAPITG 840
             ++Y   V   +E+GE +    T         PD  +  + D   + + +   R + PI G
Sbjct: 13577 KEYTFRVSAENENGEGTPSEITVVARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPIKG 13636

Query: 841   YRIVYSPSVE--------GSSTELNLPETANSVTLS--DLQPGV--QYNITIYAVEENQE 888
                  +PSV          + T +++  +A + TL   D Q     +Y IT+  V   +E
Sbjct: 13637 KP---APSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKE 13693

Query: 889   STPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPV 944
              T   I  +  G P   T P    ++F EVT   +T+ W PP+    S +T Y ++    
Sbjct: 13694 GT---ISIKVVGKPGIPTGP----IKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRD- 13745

Query: 945   NLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKV-----FAVSHGRESKPLTAQQTTKL-D 998
             ++  +        + T   VT L  G+ Y F+V     + V  G +S+P+ A+    + D
Sbjct: 13746 SVNNKWVTCASAVQKTTFRVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVPD 13805

Query: 999   APTNLQFVNETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGP-SVSKYPL 1053
             AP     V+    +V + WT P+    + ITGY L          ++ N  P  +  + +
Sbjct: 13806 APPPPNIVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTPIRMRDFKV 13865

Query: 1054  RNLQPASEYTVSLVAI------KGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITW 1107
               L    EY   ++AI      K +  S     +     PG    P    +T  ++ + W
Sbjct: 13866 TGLTEGLEYEFRVMAINLAGVGKPSLPSEPVVALDPIDPPGK---PEVINITRNSVTLIW 13922

Query: 1108  T-PAPRIGFKL-------GVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDG 1159
             T P    G KL          PS+       V     +  V+ L  G +Y + I+     
Sbjct: 13923 TEPKYDGGHKLTGYIVEKRDLPSKSWMKANHVNVPECAFTVTDLVEGGKYEFRIRAKNTA 13982

Query: 1160  QERDAPIVN----------KVVTPLSPPT---NLHLEANPDTGVLTV-----------SW 1195
                 AP  +          +  T +  PT    L ++A  DT VL             SW
Sbjct: 13983 GAISAPSESTETIICKDEYEAPTIVLDPTIKDGLTIKAG-DTIVLNAISILGKPLPKSSW 14041

Query: 1196  ERS----TTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVK 1251
              ++       DIT  +IT+TPT+     +++     D    T    +P        +  K
Sbjct: 14042 SKAGKDIRPSDIT--QITSTPTSSML--TIKYATRKDAGEYTITATNP--------FGTK 14089

Query: 1252  DDKESVPISDTIIPEVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGEGIPI 1311
              +   V + D  +P  P   ++S  +++     L WTP         +  ++   E   +
Sbjct: 14090 VEHVKVTVLD--VPGPPGPVEIS--NVSAEKATLTWTPPLEDGGSPIKSYILEKRETSRL 14145

Query: 1312  FEDFVDSSVG--YYTVTGLEPGIDYDISVITLINGG-----ESAPTTLTQQTAVP-PPTD 1363
                 V   +    +  T L  G +Y   V  + + G     +S P  +  +   P PP  
Sbjct: 14146 LWTVVSEDIQSCRHVATKLIQGNEYIFRVSAVNHYGKGEPVQSEPVKMVDRFGPPGPPEK 14205

Query: 1364  LRFTNIGPDTMRVTWAPP---PSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLL 1420
                +N+  +T  V+W  P      ++T + V     K+   V  +    SD    +T L 
Sbjct: 14206 PEVSNVTKNTATVSWKRPVDDGGSEITGYHVERREKKSLRWVRAIKTPVSDLRCKVTGLQ 14265

Query: 1421  PGTEYVVSVSSVYEQHESTPLRGRQKTGLDS-------PTGIDFSDITANSFTVHWIAPR 1473
              G+ Y   VS+        P        +         P+    +D T  S ++ W  P 
Sbjct: 14266 EGSTYEFRVSAENRAGIGPPSEASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLAWGKPH 14325

Query: 1474  ----ATITGYRIRHHPEHFSGRPREDRVPHSR-NSITLTNLTPGTEYVVSIVALN--GRE 1526
                   ITGY + H         ++      R     + +L    +Y   I A+N  G  
Sbjct: 14326 YDGGLEITGYVVEHQKVGDEAWIKDTTGTALRITQFVVPDLQTKEKYNFRISAINDAGVG 14385

Query: 1527  ESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFT 1586
             E  ++   +    ++  D E+ A    +L++      +++R +    G      P  E T
Sbjct: 14386 EPAVIPDVEIVEREMAPDFELDAELRRTLVV---RAGLSIRIFVPIKGR-----PAPEVT 14437

Query: 1587  -VPGSKSTATISGLKPGVDYTITVYAVTGRGD---------SPASSKPISINYRTEIDKP 1636
                 + +    + ++    +T+ +     R D         +PA  K   +N R  +D P
Sbjct: 14438 WTKDNINLKNRANIENTESFTLLIIPECNRYDTGKFVMTIENPAGKKSGFVNVRV-LDTP 14496

Query: 1637  S---QMQVTDVQDNSISVKW----LPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMT 1689
                  ++ TD+  +S+++ W    +   S +T Y V            T T    +    
Sbjct: 14497 GPVLNLRPTDITKDSVTLHWDLPLIDGGSRITNYIVEKREATRKS-YSTATTKCHKCTYK 14555

Query: 1690  IEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDR----PKGLAFTDVDVDSIKIAWES 1745
             + GL    EY   V A+N  G  +P   T           P  L   D+   ++ +AW  
Sbjct: 14556 VTGLSEGCEYFFRVMAENEYGIGEPTETTEPVKASEAPSPPDSLNIMDITKSTVSLAWPK 14615

Query: 1746  PQ----GQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHD--- 1798
             P+     +++ Y +                 G E    ++ L  G EYT  V+A++    
Sbjct: 14616 PKHDGGSKITGYVIEAQRKGSDQWTHITTVKGLE--CVVRNLTEGEEYTFQVMAVNSAGR 14673

Query: 1799  --DMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPM 1856
                 ES+P+I  + T +P        Q    + +       + + G R + T   K G  
Sbjct: 14674 SAPRESRPVIVKEQTMLPELDLRGIYQKLVIAKAGDNIKVEIPVLG-RPKPTVTWKKGDQ 14732

Query: 1857  -----KEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVS----- 1906
                  + +N    ++S +++ +    + +   Y     LT+R   G V  +  +      
Sbjct: 14733 ILKQTQRVNFETTATSTILN-INECVRSDSGPY----PLTARNIVGEVGDVITIQVHDIP 14787

Query: 1907  --PPRRARVTDATETTITISWRTKTE----TITGFQVDAVPANGQTPIQRTIKPDVRSYT 1960
               P    +  + +   +T SW          I+ + V+    +  T ++        +Y 
Sbjct: 14788 GPPTGPIKFDEVSSDFVTFSWDPPENDGGVPISNYVVEMRQTDSTTWVELATTVIRTTYK 14847

Query: 1961  ITGLQPGTDYKIYL-----YTLNDNARSSPVVIDASTAIDAPSNL-RFLATTPNSLLVSW 2014
              T L  G +Y+  +     Y +     S+ +V +    +  P    +  A T +S+ +SW
Sbjct: 14848 ATRLTTGLEYQFRVKAQNRYGVGPGITSACIVANYPFKVPGPPGTPQVTAVTKDSMTISW 14907

Query: 2015  QPP----RARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNN 2070
               P     + I GY ++ ++      + V +          +GL  G  Y   VIA    
Sbjct: 14908 HEPLSDGGSPILGYHVERKERNGILWQTVSKALVPGNIFKSSGLTDGIAYEFRVIAENMA 14967

Query: 2071  QKSEP 2075
              KS+P
Sbjct: 14968 GKSKP 14972



 Score =  116 bits (291), Expect = 2e-25
 Identities = 288/1381 (20%), Positives = 498/1381 (36%), Gaps = 191/1381 (13%)

Query: 766  LDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDT 825
            +D  +  TS  I +   G K    +   ++ G+    ++      P    +  V +  D 
Sbjct: 6673 IDTTAEQTSFRILEAKKGDKGRYKIVLQNKHGKAEGFINLKVIDVPGPVRNLEVTETFDG 6732

Query: 826  SIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETAN-SVTLSDLQPG-VQYNIT 879
             + + W  P     + I GY +V    ++  +  L      +   T++ LQ G V+Y   
Sbjct: 6733 EVSLAWEEPLTDGGSKIIGY-VVERRDIKRKTWVLATDRAESCEFTVTGLQKGGVEYLFR 6791

Query: 880  IYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVT 935
            + A        PV          + D    P ++   +V    V++ W PPE    + +T
Sbjct: 6792 VSARNRVGTGEPVETDNPVEARSKYDVPGPPLNVTITDVNRFGVSLTWEPPEYDGGAEIT 6851

Query: 936  GYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTT 995
             Y +++               + +  A VT +  G  Y F+V A +     KP  A    
Sbjct: 6852 NYVIELRDKTSIRWDTAMTVRAEDLSATVTDVVEGQEYSFRVRAQNRIGVGKPSAATPFV 6911

Query: 996  KL-------DAPTNLQFVNETDSTVLVRWTPP----RAQITGYRLTVGLTRRGQPR---- 1040
            K+         P NL   ++T S+V ++W PP     + I GY   +     G+      
Sbjct: 6912 KVADPIERPSPPVNLTSSDQTQSSVQLKWEPPLKDGGSPILGY--IIERCEEGKDNWIRC 6969

Query: 1041 QYNVGPSVSKYPLRNLQPASE--YTVSLVAIKGNQESPKATGVFTT----LQPGSSIPPY 1094
               + P ++ Y +  L+  ++  Y VS     G  +  +  G  T     ++P   +  +
Sbjct: 6970 NMKLVPELT-YKVTGLEKGNKYLYRVSAENKAGVSDPSEILGPLTADDAFVEPTMDLSAF 7028

Query: 1095 NTEV-----TETTIVI--TWTPAPRIGFKLGVRPSQGGEAPREVT-SDSGSIVVSGLTPG 1146
               +        TI++  T  P P   +  G +  + G+  +  T S    +V+S     
Sbjct: 7029 KDGLEVIVPNPITILVPSTGYPRPTATWCFGDKVLETGDRVKMKTLSAYAELVISPSERS 7088

Query: 1147 VEYVYTIQVLRDGQERDAPI-VNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPD--- 1202
             + +YT+++    +     I VN +  P +P      +   D+  LT  WE    PD   
Sbjct: 7089 DKGIYTLKLENRVKTISGEIDVNVIARPSAPKELKFGDITKDSVHLT--WE---PPDDDG 7143

Query: 1203 ---ITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSV------------ 1247
               +TGY +     + +    + + V       T  +L  G EY   V            
Sbjct: 7144 GSPLTGYVVEKREVSRKTWTKVMDFV--TDLEFTVPDLVQGKEYLFKVCARNKCGPGEPA 7201

Query: 1248 YTVKDDKESVPISDTIIPEVPQLTDLSFVDITDSSIGLRWTPLNS---STIIGYRITVVA 1304
            Y  +    S P +   +P+ P+  ++ + D T +SI L W P  +   S I GY +    
Sbjct: 7202 YVDEPVNMSTPAT---VPDPPE--NVKWRDRTANSIFLTWDPPKNDGGSRIKGYIVERCP 7256

Query: 1305 AGE------GIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQ--- 1355
             G       G P+ E  ++       VTGLE G  Y   V  L   G S P+  T++   
Sbjct: 7257 RGSDKWVACGEPVAETKME-------VTGLEEGKWYAYRVKALNRQGASKPSRPTEEIQA 7309

Query: 1356 --TAVPPPTDLRFTNIGPDTMR----------VTWAPPPSIDLTNFLVRYSPVKNEEDVA 1403
              T   P   L    +   T++          VT  P P I  T    +   +  ++   
Sbjct: 7310 VDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWT----KADMILKQDKRI 7365

Query: 1404 ELSISPSDNAVVLTNLL---PGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDI 1460
             +   P  + V + +      GT  + +V+          +    K G   P   D +D+
Sbjct: 7366 TIENVPKKSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNVLDKPG--PPAAFDITDV 7423

Query: 1461 TANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRNS------ITLTNLT 1510
            T  S  + W  PR    + IT Y +         R  +  V H  +S         T L 
Sbjct: 7424 TNESCLLTWNPPRDDGGSKITNYVVER-------RATDSEVWHKLSSTVKDTNFKATKLI 7476

Query: 1511 PGTEYVVSIVALN------GREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAP-- 1562
            P  EY+  + A N        + SP+    Q      P  LE    T  ++ ++W  P  
Sbjct: 7477 PNKEYIFRVAAENMYGVGEPVQASPITAKYQFDPPGPPTRLEPSDITKDAVTLTWCEPDD 7536

Query: 1563 --AVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYA--VTGRGDS 1618
                 +  Y +   +   +  V+   +P   +T  + GL     Y   V A  + G G  
Sbjct: 7537 DGGSPITGYWVERLDPDTDKWVRCNKMPVKDTTYRVKGLTNKKKYRFRVLAENLAGPGKP 7596

Query: 1619 PASSKPISINYRTEID---KPSQMQVTDVQDNSISVKWL----PSSSPVTGYRVTTTPKN 1671
              S++PI I  +  ID    P +  V DV   S+ + W        + +  Y V    K 
Sbjct: 7597 SKSTEPILI--KDPIDPPWPPGKPTVKDVGKTSVRLNWTKPEHDGGAKIESY-VIEMLKT 7653

Query: 1672 GPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQP-------LVQTAVTNID 1724
            G         G   T+  + GL    EY   V A N +GES+P       L +  +    
Sbjct: 7654 GTDEWVRVAEGVPTTQHLLPGLMEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPS 7713

Query: 1725 RPKGLAFTDVDVDSIKIAWESPQ----GQVSRYRVTYSSPEDGIHELFPAPDG--EEDTA 1778
             P+ L   ++  ++  + W  P+      ++ Y V      D   + +   D   ++   
Sbjct: 7714 PPRWLEVINITKNTADLKWTVPEKDGGSPITNYIV---EKRDVRRKGWQTVDTTVKDTKC 7770

Query: 1779 ELQGLRPGSEYTVSVVAL-------HDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSA 1831
             +  L  GS Y   V A        + ++E   L     T    P  L    VT   +  
Sbjct: 7771 TVTPLTEGSLYVFRVAAENAIGQSDYTEIEDSVLAKDTFTTPGPPYALAVVDVTKRHVDL 7830

Query: 1832 QWTPPNVQ--LTGYRVRVTPKEKTGP--MKEINLAPDSSSVVVSGLMVATKYEVSVYALK 1887
            +W PP         R  +  KE+ G   +K    A    +  V+ ++  T+ +  V A  
Sbjct: 7831 KWEPPKNDGGRPIQRYVIEKKERLGTRWVKAGKTAGPDCNFRVTDVIEGTEVQFQVRAEN 7890

Query: 1888 DTLTSRPAQGV-VTTLEN----VSPPRRARVTDATETTITISWRTKTET----ITGFQVD 1938
            +     P++   + ++E+     SPP    VTDA    I I+W+   +     I G+ V+
Sbjct: 7891 EAGVGHPSEPTEILSIEDPTSPPSPPLDLHVTDAGRKHIAIAWKPPEKNGGSPIIGYHVE 7950

Query: 1939 AVPANGQTPIQRTIKP--DVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDA 1996
              P   +  ++   +P  D++     G+ P  +Y + +  +N    S P  I  +     
Sbjct: 7951 MCPVGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAIGVSEPSEISENVVAKD 8010

Query: 1997 P 1997
            P
Sbjct: 8011 P 8011



 Score =  115 bits (288), Expect = 5e-25
 Identities = 291/1449 (20%), Positives = 530/1449 (36%), Gaps = 173/1449 (11%)

Query: 785   KYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPT-VDQVDDTSIVVRWSRPQ----APIT 839
             +Y++ +  ++  G +S+ ++      P  P  P  ++ +      + W RPQ    A I 
Sbjct: 19487 QYVLTLKNVA--GTRSVAVNCKVLDKPGPPAGPLEINGLTAEKCSLSWGRPQEDGGADID 19544

Query: 840   GYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETT 899
              Y +    +   + T         S  ++ L  G +Y   +  V +     P+    E+ 
Sbjct: 19545 YYIVEKRETSHLAWTICEGELQMTSCKVTKLLKGNEYIFRVTGVNKYGVGEPL----ESV 19600

Query: 900   GTPRSD--TVPSP-RDLQFVEVTDVKVTIMWTPPES----AVTGYRVDVIPVN-LPGEHG 951
                  D  TVPSP   L+   VT   +T+ W+ PES     ++GY ++    N L     
Sbjct: 19601 AIKALDPFTVPSPPTSLEITSVTKESMTLCWSRPESDGGSEISGYIIERREKNSLRWVRV 19660

Query: 952   QRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNL-------Q 1004
              + P+  +   + TGL  G  Y ++V+A +    S P       + + P  L       +
Sbjct: 19661 NKKPVY-DLRVKSTGLREGCEYEYRVYAENAAGLSLPSETSPLIRAEDPVFLPSPPSKPK 19719

Query: 1005  FVNETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPAS 1060
              V+   +T+ + W  P     A ITGY +    +     +        ++Y +  L   +
Sbjct: 19720 IVDSGKTTITIAWVKPLFDGGAPITGYTVEYKKSDDTDWKTSIQSLRGTEYTISGLTTGA 19779

Query: 1061  EYTVSLVAIK---GNQESPKATGVFTTLQPGSSIPPYNTEVTETTIV-----ITWT---- 1108
             EY   + ++     +  S  +       +    +   ++E+ +T IV      T T    
Sbjct: 19780 EYVFRVKSVNKVGASDPSDSSDPQIAKEREEEPLFDIDSEMRKTLIVKAGASFTMTVPFR 19839

Query: 1109  --PAPRIGFKLGVRPSQG--GEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDA 1164
               P P +   L  +P       A  + T    S+ +          YT+ +         
Sbjct: 19840 GRPVPNV---LWSKPDTDLRTRAYVDTTDSRTSLTIENANRNDSGKYTLTIQNVLSAASL 19896

Query: 1165  PIVNKVVTPLSPPTNLHLE-ANPDTGVLTVSW---ERSTTPDITGYRITTTPTNGQQGNS 1220
              +V KV+    PPTN+ ++    ++ VL  SW   E      +  Y I     + +   S
Sbjct: 19897 TLVVKVLDTPGPPTNITVQDVTKESAVL--SWDVPENDGGAPVKNYHIEKREASKKAWVS 19954

Query: 1221  LE--------EVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPEVPQLTD 1272
             +         +V +  + +  +  +S   E+ V +    + KE V I++   P  P+   
Sbjct: 19955 VTNNCNRLSYKVTNLQEGAIYYFRVSGENEFGVGIPA--ETKEGVKITEK--PSPPE--K 20008

Query: 1273  LSFVDITDSSIGLRWTPLN---SSTIIGYRITVVAAGEGIPIFEDFVDSSVG---YYTVT 1326
             L    I+  S+ L W        S I+ Y +  +  G+     +++V  +V    ++ V+
Sbjct: 20009 LGVTSISKDSVSLTWLKPEHDGGSRIVHYVVEALEKGQ-----KNWVKCAVAKSTHHVVS 20063

Query: 1327  GLEPGIDYDISVITLINGGESAPT-----TLTQQTAVPPPTDLRFTNIGPDTMRVTWAPP 1381
             GL    +Y   V      G S P       L ++   PP  D++  N    T+ V     
Sbjct: 20064 GLRENSEYFFRVFAENQAGLSDPRELLLPVLIKEQLEPPEIDMK--NFPSHTVYVRAGSN 20121

Query: 1382  PSIDLTNFLVRYSPVKNEEDVAELSISPSDNA-VVLTNLLPGTEYVVSVSSVYEQHESTP 1440
               +D+         V    D   L  +   N  +   NL    +  V+  +   +  +  
Sbjct: 20122 LKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADAGRYEITAAN 20181

Query: 1441  LRGRQKTGLD--------SPTG-IDFSDITANSFTVHWIAPR----ATITGYRIRHHPEH 1487
               G  K  ++         PTG +  SDIT  S T+ W  P+    + +T Y +    E 
Sbjct: 20182 SSGTTKAFINIVVLDRPGPPTGPVVISDITEESVTLKWEPPKYDGGSQVTNYILLKR-ET 20240

Query: 1488  FSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGR------EESPLLIGQQSTVSDV 1541
              +    E     +R  + +  LT G EY   I A N        + + + +    T    
Sbjct: 20241 STAVWTEVSATVARTMMKVMKLTTGEEYQFRIKAENRFGISDHIDSACVTVKLPYTTPGP 20300

Query: 1542  PRDLEVVAATPTSLLISWDAPAVT----VRYYRITYGETGGNSPVQEFTVPGSKSTATIS 1597
             P    V   T  S+ + W  P       V  Y +   +       +   +    +   ++
Sbjct: 20301 PSTPWVTNVTRESITVGWHEPVSNGGSAVVGYHLEMKDRNSILWQKANKLVIRTTHFKVT 20360

Query: 1598  GLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKW---- 1653
              +  G+ Y   VYA    G    S     +      + P  +++TD+  NS+S+ W    
Sbjct: 20361 TISAGLIYEFRVYAENAAGVGKPSHPSEPVLAIDACEPPRNVRITDISKNSVSLSWQQPA 20420

Query: 1654  LPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE-S 1712
                 S +TGY V          TK       +T+  I GL    +Y   V+A+N  G  S
Sbjct: 20421 FDGGSKITGYIVERRDLPDGRWTKASFTNVTETQFIISGLTQNSQYEFRVFARNAVGSIS 20480

Query: 1713  QPL-VQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAP 1771
              P  V   +T ID   G    D+ ++  ++  +   G   + R   S       E +   
Sbjct: 20481 NPSEVVGPITCIDSYGGPVI-DLPLEYTEVV-KYRAGTSVKLRAGISGKPAPTIEWYK-D 20537

Query: 1772  DGEEDTAELQGLRPGSEYTVSVVALHDDMES-------QPLIGTQSTAI---------PA 1815
             D E  T  L  +   ++    ++   D + S       +  +G+ S  I         P 
Sbjct: 20538 DKELQTNALVCVENTTDLASILIKDADRLNSGCYELKLRNAMGSASATIRVQILDKPGPP 20597

Query: 1816  PTDLKFTQVTPTSLSAQWTPP----NVQLTGYRVRVTPKEKTGPM--KEINLAPDSSSVV 1869
                ++F  VT   ++  W PP      ++T Y   +  K +T  +    ++   +   + 
Sbjct: 20598 GGPIEFKTVTAEKITLLWRPPADDGGAKITHY---IVEKRETSRVVWSMVSEHLEECIIT 20654

Query: 1870  VSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENV----SPPRRARVTDATETTITISW 1925
              + ++   +Y   V A+       P +      +N      PP    VT  T+ ++T+ W
Sbjct: 20655 TTKIIKGNEYIFRVRAVNKYGIGEPLESDSVVAKNAFVTPGPPGIPEVTKITKNSMTVVW 20714

Query: 1926  RTKT----ETITGFQV---DAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLN 1978
                       I+G+ +   D         ++ TI+ D R   +TGL   +DY+  +  +N
Sbjct: 20715 SRPIADGGSDISGYFLEKRDKKSLGWFKVLKETIR-DTRQ-KVTGLTENSDYQYRVCAVN 20772

Query: 1979  DNAR---SSPVVI-DASTAIDAP---SNLRFLATTPNSLLVSWQPP----RARITGYIIK 2027
                +   S P     A+  ID P   + +R   +T +S+ + W  P     + +TGY+++
Sbjct: 20773 AAGQGPFSEPSEFYKAADPIDPPGPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVVE 20832

Query: 2028  YEKPGSPPREVVP-RPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQKT 2086
               +        V  +     TE  ++ L+PG  Y   V A+    + EP I   + VQ  
Sbjct: 20833 IRQGEEEEWTTVSTKGEVRTTEYVVSNLKPGVNYYFRVSAVNCAGQGEP-IEMNEPVQAK 20891

Query: 2087  PFVTHPGYD 2095
               +  P  D
Sbjct: 20892 DILEAPEID 20900



 Score =  115 bits (287), Expect = 7e-25
 Identities = 310/1519 (20%), Positives = 528/1519 (34%), Gaps = 242/1519 (15%)

Query: 758  EEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLI---LSTSQTTAPDAP 814
            E GD  +   L + A  V    + P  +    +Y +  +     I   +  +    P AP
Sbjct: 7064 ETGDRVKMKTLSAYAELV----ISPSERSDKGIYTLKLENRVKTISGEIDVNVIARPSAP 7119

Query: 815  PDPTVDQVDDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTLSDL 870
             +     +   S+ + W  P     +P+TGY +        + T++    T    T+ DL
Sbjct: 7120 KELKFGDITKDSVHLTWEPPDDDGGSPLTGYVVEKREVSRKTWTKVMDFVTDLEFTVPDL 7179

Query: 871  QPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP 930
              G +Y   + A  +     P  + +    +  +     P ++++ + T   + + W PP
Sbjct: 7180 VQGKEYLFKVCARNKCGPGEPAYVDEPVNMSTPATVPDPPENVKWRDRTANSIFLTWDPP 7239

Query: 931  E----SAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRES 986
            +    S + GY V+  P           P++  T  EVTGL  G  Y ++V A++    S
Sbjct: 7240 KNDGGSRIKGYIVERCPRGSDKWVACGEPVA-ETKMEVTGLEEGKWYAYRVKALNRQGAS 7298

Query: 987  KP---------------------------LTAQQTTKLDAPTNLQFVNETDSTVLVRWTP 1019
            KP                           LT +  TK++ P  +    E   T    WT 
Sbjct: 7299 KPSRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKIT----WT- 7353

Query: 1020 PRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKAT 1079
             +A +   +    +T    P++  V    SK           Y +  V + G   +    
Sbjct: 7354 -KADMI-LKQDKRITIENVPKKSTVTIVDSK-----RSDTGTYIIEAVNVCGRATAVVEV 7406

Query: 1080 GVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRI--GFKLGVRPSQGGEAPREVTSDSGS 1137
             V    +PG       T+VT  + ++TW P PR   G K+     +      EV     S
Sbjct: 7407 NVLD--KPGPPAAFDITDVTNESCLLTWNP-PRDDGGSKITNYVVERRATDSEVWHKLSS 7463

Query: 1138 IV------VSGLTPGVEYVYTI---QVLRDGQERDA-PIVNKV-VTPLSPPTNLHLEANP 1186
             V       + L P  EY++ +    +   G+   A PI  K    P  PPT L   ++ 
Sbjct: 7464 TVKDTNFKATKLIPNKEYIFRVAAENMYGVGEPVQASPITAKYQFDPPGPPTRLE-PSDI 7522

Query: 1187 DTGVLTVSW---ERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEY 1243
                +T++W   +      ITGY +     +  +     ++   D ++     L+   +Y
Sbjct: 7523 TKDAVTLTWCEPDDDGGSPITGYWVERLDPDTDKWVRCNKMPVKD-TTYRVKGLTNKKKY 7581

Query: 1244 NVSVYTV------KDDKESVP--ISDTIIPEVPQLTDLSFVDITDSSIGLRWTPL---NS 1292
               V         K  K + P  I D I P  P     +  D+  +S+ L WT       
Sbjct: 7582 RFRVLAENLAGPGKPSKSTEPILIKDPIDPPWPP-GKPTVKDVGKTSVRLNWTKPEHDGG 7640

Query: 1293 STIIGYRITVVAAG--------EGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLING 1344
            + I  Y I ++  G        EG+P  +         + + GL  G +Y   V  +   
Sbjct: 7641 AKIESYVIEMLKTGTDEWVRVAEGVPTTQ---------HLLPGLMEGQEYSFRVRAVNKA 7691

Query: 1345 GESAPT-----TLTQQTAVP--PPTDLRFTNIGPDTMRVTWAPPP---SIDLTNFLVRYS 1394
            GES P+      L ++   P  PP  L   NI  +T  + W  P       +TN++V   
Sbjct: 7692 GESEPSEPSDPVLCREKLYPPSPPRWLEVINITKNTADLKWTVPEKDGGSPITNYIVEKR 7751

Query: 1395 PVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVS-------SVYEQHESTPLRGRQKT 1447
             V+  +    +  +  D    +T L  G+ YV  V+       S Y + E + L     T
Sbjct: 7752 DVR-RKGWQTVDTTVKDTKCTVTPLTEGSLYVFRVAAENAIGQSDYTEIEDSVLAKDTFT 7810

Query: 1448 GLDSPTGIDFSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRNS 1503
                P  +   D+T     + W  P+      I  Y I       +   +  +      +
Sbjct: 7811 TPGPPYALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKERLGTRWVKAGKTAGPDCN 7870

Query: 1504 ITLTNLTPGTEYVVSIVALN----GREESP---LLIGQQSTVSDVPRDLEVVAATPTSLL 1556
              +T++  GTE    + A N    G    P   L I   ++    P DL V  A    + 
Sbjct: 7871 FRVTDVIEGTEVQFQVRAENEAGVGHPSEPTEILSIEDPTSPPSPPLDLHVTDAGRKHIA 7930

Query: 1557 ISWDAPAVTVRYYRITYGETGGNSPVQEFTVP----GSKSTATIS-------------GL 1599
            I+W  P            E  G SP+  + V     G++    ++             G+
Sbjct: 7931 IAWKPP------------EKNGGSPIIGYHVEMCPVGTEKWMRVNSRPIKDLKFKVEEGV 7978

Query: 1600 KPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSP 1659
             P  +Y + V AV   G     S+P  I+       P      D++ + I V      S 
Sbjct: 7979 VPDKEYVLRVRAVNAIG----VSEPSEISENVVAKDPDCKPTIDLETHDIIVIEGEKLSI 8034

Query: 1660 VTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYA---------QNPSG 1710
               +R    P         +    D+  M  + +   +E   SV A         +N  G
Sbjct: 8035 PVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLG 8094

Query: 1711 ESQPLVQTAVTNIDRP-KGLAFTDVDVDSIKIAWESPQ--GQVSRYRVTYSSPEDGIHEL 1767
             +   +   V  +  P K +  +D+   S K+ WE P+  G            E G    
Sbjct: 8095 SATASINVKVIGLPGPCKDIKASDITKSSCKLTWEPPEFDGGTPILHYVLERREAGRRTY 8154

Query: 1768 FPAPDGEEDTA-ELQGLRPGSEYTVSVVALH-----DDME-SQPLIGTQSTAIP-APTDL 1819
             P   GE   +  ++ L P  EY   V A++     + +E   P+I       P  P D+
Sbjct: 8155 IPVMSGENKLSWTVKDLIPNGEYFFRVKAVNKVGGGEYIELKNPVIAQDPKQPPDPPVDV 8214

Query: 1820 KFTQVTPTSLSAQWTPP----NVQLTGYRV-RVTPKEKTGPMKEINLAPDSSSVVVSGLM 1874
            +    T  +++  W PP      ++ GY + ++   E+       +L P   +    GL 
Sbjct: 8215 EVHNPTAEAMTITWKPPLYDGGSKIMGYIIEKIAKGEERWKRCNEHLVP-ILTYTAKGLE 8273

Query: 1875 VATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTI------------- 1921
               +Y+  V A      S P++    T + V P    +V   T   +             
Sbjct: 8274 EGKEYQFRVRAENAAGISEPSRATPPT-KAVDPIDAPKVILRTSLEVKRGDEIALDASIS 8332

Query: 1922 -----TISWRTKTETITGFQVD--------------------AVPANGQTPIQRTIKPDV 1956
                 TI+W      I   ++                      +P   +  I  + K + 
Sbjct: 8333 GSPYPTITWIKDENVIVPEEIKKRAAPLVRRRKGEVQEEEPFVLPLTQRLSIDNSKKGES 8392

Query: 1957 RSYTITGLQPGTDYKIYLYTL-NDNA-RSSPVVIDASTAIDAPSNLRFLATTPNSLLVSW 2014
            +      L+P  D+ +Y+  + ND+    +P  +        P N  F      S+L  W
Sbjct: 8393 QLRVRDSLRP--DHGLYMIKVENDHGIAKAPCTVSVLDTPGPPINFVFEDIRKTSVLCKW 8450

Query: 2015 QPP----RARITGYIIKYEKPGSPPRE-VVPRPRPGVTEATITGLEPGTEYTIYVIALKN 2069
            +PP     + I  Y ++ +    P  E +V        + ++T L  G EY ++ +  +N
Sbjct: 8451 EPPLDDGGSEIINYTLEKKDKTKPDSEWIVVTSTLRHCKYSVTKLIEGKEY-LFRVRAEN 8509

Query: 2070 NQKSEPLIGRKKTVQKTPF 2088
                 P    K  V K PF
Sbjct: 8510 RFGPGPPCVSKPLVAKDPF 8528



 Score =  114 bits (286), Expect = 9e-25
 Identities = 280/1356 (20%), Positives = 495/1356 (36%), Gaps = 217/1356 (16%)

Query: 727   SVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQ--YLDLPSTA--TSVNIPDLLP 782
             +VTE+T+   V+SW    D   G ++++ + ++ +  +  + ++ S    T + +  LL 
Sbjct: 15191 AVTEVTSEKCVLSWFPPLDD-GGAKIDHYIVQKRETSRLAWTNVASEVQVTKLKVTKLLK 15249

Query: 783   GRKYI-----VNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAP 837
             G +YI     VN Y + E  E   +L+ +    PD P +P V  +   S+VV W  P + 
Sbjct: 15250 GNEYIFRVMAVNKYGVGEPLESEPVLAVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDS- 15308

Query: 838   ITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQ-------PGVQYNITIYAVEENQEST 890
               G   + +  VE            N  TL+DL+        G +Y   I A      S 
Sbjct: 15309 -DGGSEIINYIVERRDKAGQRWIKCNKKTLTDLRYKVSGLTEGHEYEFRIMAENAAGISA 15367

Query: 891   PVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNL 946
             P                  P + + ++ +   ++I W  P     S +TGY V++    L
Sbjct: 15368 PSPTSPFYKACDTVFKPGPPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIA---L 15424

Query: 947   PGEHGQRLPIS----RNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLD---A 999
             P E   ++       + T   +TGL+    Y  +++A++     +P     T K +    
Sbjct: 15425 PEEDEWQIVTPPAGLKATSYTITGLTENQEYKIRIYAMNSEGLGEPALVPGTPKAEDRML 15484

Query: 1000  PTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPR---QYNVGPSVSKYPLRNL 1056
             P  ++   +    V +R           RL V +  R  P      + G S+ K    ++
Sbjct: 15485 PPEIELDADLRKVVTIR------ACCTLRLFVPIKGRPAPEVKWARDHGESLDK---ASI 15535

Query: 1057  QPASEYTVSLVAIKGNQESPK----------ATGVFTTLQ----PGSSIPPYNTEVTETT 1102
             +  S YT+ +V      +S K          +   F  ++    PG        EVT+T+
Sbjct: 15536 ESTSSYTLLIVGNVNRFDSGKYILTVENSSGSKSAFVNVRVLDTPGPPQDLKVKEVTKTS 15595

Query: 1103  IVITWTPAPRI--GFKLGVRPSQGGEAPREVTS------DSGSIVVSGLTPGVEYVYTIQ 1154
             + +TW P P +  G K+     +  E+ R+  S         S  V  L  G  Y +  +
Sbjct: 15596 VTLTWDP-PLLDGGSKIKNYIVEKRESTRKAYSTVATNCHKTSWKVDQLQEGCSYYF--R 15652

Query: 1155  VLRDGQ------ERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPD---ITG 1205
             VL + +         A  V     PL P     ++   ++  +++SWE+        I G
Sbjct: 15653 VLAENEYGIGLPAETAESVKASERPLPPGKITLMDVTRNS--VSLSWEKPEHDGGSRILG 15710

Query: 1206  YRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYT-----VKDDKE-SVPI 1259
             Y I    T G    +    V   +++ T   L  G EY+  V       + D ++ SVP+
Sbjct: 15711 Y-IVEMQTKGSDKWATCATVKVTEATIT--GLIQGEEYSFRVSAQNEKGISDPRQLSVPV 15767

Query: 1260  --SDTIIPEVPQLTDLSFVDITDSSI------------GLRW----TPLNSSTIIGYRIT 1301
                D +IP   +L   +F  +    +             + W     PL  +T +    T
Sbjct: 15768 IAKDLVIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAEST 15827

Query: 1302  VVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTL---TQQTAV 1358
                    +   +D     VG+Y              V+ L N    A  TL         
Sbjct: 15828 ---ENNSLLTIKDACREDVGHY--------------VVKLTNSAGEAIETLNVIVLDKPG 15870

Query: 1359  PPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAE---LSISPSDNAVV 1415
             PP   ++   +  D++ ++W  PP  D  + +  Y   K +        +S + +   + 
Sbjct: 15871 PPTGPVKMDEVTADSITLSWG-PPKYDGGSSINNYIVEKRDTSTTTWQIVSATVARTTIK 15929

Query: 1416  LTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTG-----LDSPTGIDFSDITA-NSFTVHW 1469
                L  G EY   +++     +ST L            +  P G     +++ +S  V W
Sbjct: 15930 ACRLKTGCEYQFRIAAENRYGKSTYLNSEPTVAQYPFKVPGPPGTPVVTLSSRDSMEVQW 15989

Query: 1470  IAP----RATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGR 1525
               P     + + GY +     +     + ++ P  +     T L  G EY   + A    
Sbjct: 15990 NEPISDGGSRVIGYHLERKERNSILWVKLNKTPIPQTKFKTTGLEEGVEYEFRVSA---- 16045

Query: 1526  EESPLLIGQQSTVSD--VPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQ 1583
              E+ + IG+ S VS+  V RD       P +++++ +  +VT+++ + TY    G S + 
Sbjct: 16046 -ENIVGIGKPSKVSECYVARDPCDPPGRPEAIIVTRN--SVTLQWKKPTY---DGGSKIT 16099

Query: 1584  EFTVPGS--------KSTAT--------ISGLKPGVDYTITVYAVTGRG-DSPASSKPIS 1626
              + V           K++ T        ++GL     Y   V A    G  S  S    +
Sbjct: 16100 GYIVEKKELPEGRWMKASFTNIIDTHFEVTGLVEDHRYEFRVIARNAAGVFSEPSESTGA 16159

Query: 1627  INYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQT 1686
             I  R E+D P        +D  +             ++V       P PT     G  + 
Sbjct: 16160 ITARDEVDPPRISMDPKYKDTIV-------VHAGESFKVDADIYGKPIPTIQWIKGDQEL 16212

Query: 1687  EMTIEGLQPTVEYVVS---------------VYAQNPSGESQPLVQTAVTNIDRP----K 1727
               T      + ++  S               + A+N +GE    V   V  +DRP     
Sbjct: 16213 SNTARLEIKSTDFATSLSVKDAVRVDSGNYILKAKNVAGERSVTVNVKV--LDRPGPPEG 16270

Query: 1728  GLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHEL-FPAPDGEEDT--AELQGLR 1784
              +  + V  +   +AW+ P        + Y         L +   D    T   ++  L 
Sbjct: 16271 PVVISGVTAEKCTLAWKPPLQDGGSDIINYIVERRETSRLVWTVVDANVQTLSCKVTKLL 16330

Query: 1785  PGSEYTVSVVALH-----DDMESQPLIGTQSTAIP-APTDLKFTQVTPTSLSAQWTPP-- 1836
              G+EYT  ++A++     + +ES+P++      +P AP   + T VT  S+   W  P  
Sbjct: 16331 EGNEYTFRIMAVNKYGVGEPLESEPVVAKNPFVVPDAPKAPEVTTVTKDSMIVVWERPAS 16390

Query: 1837  --NVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRP 1894
                 ++ GY +    KE     +          + V+GL+    YE  V A      S P
Sbjct: 16391 DGGSEILGYVLEKRDKEGIRWTRCHKRLIGELRLRVTGLIENHDYEFRVSAENAAGLSEP 16450

Query: 1895  A-----QGVVTTLENVSPPRRARVTDATETTITISW 1925
             +     Q     +    PP   +V D T +++ +SW
Sbjct: 16451 SPPSAYQKACDPIYKPGPPNNPKVIDITRSSVFLSW 16486



 Score =  114 bits (285), Expect = 1e-24
 Identities = 294/1413 (20%), Positives = 501/1413 (35%), Gaps = 193/1413 (13%)

Query: 806  SQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ----APITGYRIVYSPSVEGS-STELNLPE 860
            S+   P  P + T+  V+   + + W  P+    A IT Y I           T + +  
Sbjct: 6814 SKYDVPGPPLNVTITDVNRFGVSLTWEPPEYDGGAEITNYVIELRDKTSIRWDTAMTVRA 6873

Query: 861  TANSVTLSDLQPGVQYNITIYA-----VEENQESTPVVIQQETTGTPRSDTVPSPRDLQF 915
               S T++D+  G +Y+  + A     V +   +TP V   +    P       P +L  
Sbjct: 6874 EDLSATVTDVVEGQEYSFRVRAQNRIGVGKPSAATPFVKVADPIERPSP-----PVNLTS 6928

Query: 916  VEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGV 971
             + T   V + W PP     S + GY ++             + +      +VTGL  G 
Sbjct: 6929 SDQTQSSVQLKWEPPLKDGGSPILGYIIERCEEGKDNWIRCNMKLVPELTYKVTGLEKGN 6988

Query: 972  TYYFKVFAVSHGRESKP------LTA-----QQTTKLDA-PTNLQFVNETDSTVLVRWTP 1019
             Y ++V A +    S P      LTA     + T  L A    L+ +     T+LV  T 
Sbjct: 6989 KYLYRVSAENKAGVSDPSEILGPLTADDAFVEPTMDLSAFKDGLEVIVPNPITILVPSTG 7048

Query: 1020 -PRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKA 1078
             PR   T       L    + +      ++S Y    + P+      +  +K        
Sbjct: 7049 YPRPTATWCFGDKVLETGDRVKM----KTLSAYAELVISPSERSDKGIYTLKLENRVKTI 7104

Query: 1079 TG---VFTTLQPGSSIPPYNTEVTETTIVITWTP------APRIGFKLGVRPSQGGEAPR 1129
            +G   V    +P +       ++T+ ++ +TW P      +P  G+ +  R     E  R
Sbjct: 7105 SGEIDVNVIARPSAPKELKFGDITKDSVHLTWEPPDDDGGSPLTGYVVEKR-----EVSR 7159

Query: 1130 EVTSDSGSIV------VSGLTPGVEYVYTIQVLRDGQERDAPIVNKVV---TPLS---PP 1177
            +  +     V      V  L  G EY++ +         +   V++ V   TP +   PP
Sbjct: 7160 KTWTKVMDFVTDLEFTVPDLVQGKEYLFKVCARNKCGPGEPAYVDEPVNMSTPATVPDPP 7219

Query: 1178 TNLHLEANPDTGVLTVSWERSTTPD---ITGYRITTTPTNGQQGNSLEEVVHADQSSCTF 1234
             N+         +  ++W+         I GY +   P    +  +  E V   +   T 
Sbjct: 7220 ENVKWRDRTANSIF-LTWDPPKNDGGSRIKGYIVERCPRGSDKWVACGEPVAETKMEVT- 7277

Query: 1235 DNLSPGLEYNVSVYTVKDDKESVPISDT-------------IIPEVPQLTDLSF-----V 1276
              L  G  Y   V  +     S P   T             I  +V  L  L+      +
Sbjct: 7278 -GLEEGKWYAYRVKALNRQGASKPSRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKI 7336

Query: 1277 DITDSSIG-----LRWTPLNSSTIIGYRITVVAAGEGIP-----IFEDFVDSSVGYYTVT 1326
            ++  +  G     + WT  +       RIT+    E +P        D   S  G Y + 
Sbjct: 7337 ELPATVTGKPEPKITWTKADMILKQDKRITI----ENVPKKSTVTIVDSKRSDTGTYIIE 7392

Query: 1327 GLEPGIDYDISVITLINGGESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAPPPS--- 1383
             +             + G  +A   +       PP     T++  ++  +TW PP     
Sbjct: 7393 AVN------------VCGRATAVVEVNVLDKPGPPAAFDITDVTNESCLLTWNPPRDDGG 7440

Query: 1384 IDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSS-----VYEQHES 1438
              +TN++V      +E    +LS +  D     T L+P  EY+  V++     V E  ++
Sbjct: 7441 SKITNYVVERRATDSEV-WHKLSSTVKDTNFKATKLIPNKEYIFRVAAENMYGVGEPVQA 7499

Query: 1439 TPLRGR-QKTGLDSPTGIDFSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPR 1493
            +P+  + Q      PT ++ SDIT ++ T+ W  P     + ITGY +           R
Sbjct: 7500 SPITAKYQFDPPGPPTRLEPSDITKDAVTLTWCEPDDDGGSPITGYWVERLDPDTDKWVR 7559

Query: 1494 EDRVPHSRNSITLTNLTPGTEYVVSIVALN-------GREESPLLIGQQSTVSDVPRDLE 1546
             +++P    +  +  LT   +Y   ++A N        +   P+LI         P    
Sbjct: 7560 CNKMPVKDTTYRVKGLTNKKKYRFRVLAENLAGPGKPSKSTEPILIKDPIDPPWPPGKPT 7619

Query: 1547 VVAATPTSLLISWDAP----AVTVRYYRITYGETGGNSPVQEFTVPGSKSTA-TISGLKP 1601
            V     TS+ ++W  P       +  Y I   +TG +  V+     G  +T   + GL  
Sbjct: 7620 VKDVGKTSVRLNWTKPEHDGGAKIESYVIEMLKTGTDEWVR--VAEGVPTTQHLLPGLME 7677

Query: 1602 GVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQ---MQVTDVQDNSISVKWL---- 1654
            G +Y+  V AV   G+S  S     +  R ++  PS    ++V ++  N+  +KW     
Sbjct: 7678 GQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLEVINITKNTADLKWTVPEK 7737

Query: 1655 PSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQ- 1713
               SP+T Y V        G     T   D T+ T+  L     YV  V A+N  G+S  
Sbjct: 7738 DGGSPITNYIVEKRDVRRKGWQTVDTTVKD-TKCTVTPLTEGSLYVFRVAAENAIGQSDY 7796

Query: 1714 ------PLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQ----VSRYRVTYSSPEDG 1763
                   L +   T    P  LA  DV    + + WE P+      + RY +        
Sbjct: 7797 TEIEDSVLAKDTFTTPGPPYALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKERLGT 7856

Query: 1764 IHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPT------ 1817
                     G +    +  +  G+E    V A ++     P   T+  +I  PT      
Sbjct: 7857 RWVKAGKTAGPDCNFRVTDVIEGTEVQFQVRAENEAGVGHPSEPTEILSIEDPTSPPSPP 7916

Query: 1818 -DLKFTQVTPTSLSAQWTPPNVQ----LTGYRVRVTPKEKTGPMKEINLAP--DSSSVVV 1870
             DL  T      ++  W PP       + GY V + P   T     +N  P  D    V 
Sbjct: 7917 LDLHVTDAGRKHIAIAWKPPEKNGGSPIIGYHVEMCP-VGTEKWMRVNSRPIKDLKFKVE 7975

Query: 1871 SGLMVATKYEVSVYALKDTLTSRP---AQGVVTTLENVSP-----PRRARVTDATETTIT 1922
             G++   +Y + V A+     S P   ++ VV    +  P          V +  + +I 
Sbjct: 7976 EGVVPDKEYVLRVRAVNAIGVSEPSEISENVVAKDPDCKPTIDLETHDIIVIEGEKLSIP 8035

Query: 1923 ISWRTKTETITGFQVDAVPANGQTPIQRTIKPD-VRSYTITGLQPGTDYKIYLYTLNDNA 1981
            + +R        +  D         +  T+K D + ++         D  IY  TL +  
Sbjct: 8036 VPFRAVPVPTVSWHKDGKEVKASDRL--TMKNDHISAHLEVPKSVRADAGIYTITLENKL 8093

Query: 1982 RSSPVVIDAST-AIDAP-SNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPP 2035
             S+   I+     +  P  +++    T +S  ++W+PP       I  Y+++  + G   
Sbjct: 8094 GSATASINVKVIGLPGPCKDIKASDITKSSCKLTWEPPEFDGGTPILHYVLERREAGR-- 8151

Query: 2036 REVVP-RPRPGVTEATITGLEPGTEYTIYVIAL 2067
            R  +P          T+  L P  EY   V A+
Sbjct: 8152 RTYIPVMSGENKLSWTVKDLIPNGEYFFRVKAV 8184



 Score =  112 bits (281), Expect = 3e-24
 Identities = 353/1634 (21%), Positives = 588/1634 (35%), Gaps = 247/1634 (15%)

Query: 607   SSSGPVEVFIT----ETPSQPNSHPIQWNAPQPSHISKYILRWRP---------KNSVGR 653
             +SSG    F+T    +TP  P +  ++      +      L W P         KN V  
Sbjct: 17727 NSSGSKSAFVTVKVLDTPGPPQNLAVKEVRKDSA-----FLVWEPPIIDGGAKVKNYVID 17781

Query: 654   WKEATIPGHLN--------SYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTP 705
              +E+T   + N        S+ ++ L  G +Y  ++++  ++G                P
Sbjct: 17782 KRESTRKAYANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFG-------------VGVP 17828

Query: 706   VTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVS----ASDTVSGFRVEYELSEEGD 761
             V +        P SP      ++T+++ +S  + W          V G+ VE  +  +G 
Sbjct: 17829 VETVDAVKAAEPPSP--PGKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVE--MQPKGT 17884

Query: 762   EPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQ 821
             E   +   S   +  +  L  G++Y   V   +E G+    +      A D    P++  
Sbjct: 17885 EKWSIVAESKVCNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKL 17944

Query: 822   VDDTSIVVRWS--RPQAPITGY-RIVYSPSVEGS----STELNLPETANSVTLSDLQPGV 874
               +T  +      + + P+ G  R   S   +G     +T +N+ ETA S  L  ++ G 
Sbjct: 17945 PFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLH-IKEGN 18003

Query: 875   QYNITIYAVEENQESTPV-----VIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTP 929
             + +   Y V     +        VI  E  G P          ++F EV+   V I W P
Sbjct: 18004 KDDFGKYTVTATNSAGTATENLSVIVLEKPGPPVGP-------VRFDEVSADFVVISWEP 18056

Query: 930   PESA----VTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRE 985
             P       ++ Y V+         H     ++R T  ++T L  G  Y F++FA +   +
Sbjct: 18057 PAYTGGCQISNYIVEKRDTTTTTWHMVSATVARTTI-KITKLKTGTEYQFRIFAENRYGK 18115

Query: 986   SKPLTA-----QQTTKLDAPTNLQFVNE-TDSTVLVRWTPP----RAQITGYRLTVGLTR 1035
             S PL +     Q   K   P    FV   +   +LV+W  P      +I GY L      
Sbjct: 18116 SAPLDSKAVIVQYPFKEPGPPGTPFVTSISKDQMLVQWHEPVNDGGTKIIGYHLEQKEKN 18175

Query: 1036  RGQPRQYNVGP-SVSKYPLRNLQPASEY--TVSLVAIKGNQESPKATGVFTTLQPGSSIP 1092
                  + N  P   +K+    L    EY   VS   I G  +  K +  F    P    P
Sbjct: 18176 SILWVKLNKTPIQDTKFKTTGLDEGLEYEFKVSAENIVGIGKPSKVSECFVARDPCD--P 18233

Query: 1093  PYNTE---VTETTIVITW-TPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVE 1148
             P   E   +T   + + W  PA   G K+       G    +     G  + +  T  +E
Sbjct: 18234 PGRPEAIVITRNNVTLKWKKPAYDGGSKI------TGYIVEKKDLPDGRWMKASFTNVLE 18287

Query: 1149  YVYTIQVLRDGQERDAPIV-NKVVTPLSPPT---------------NLHLEAN-PDTGVL 1191
               +T+  L + Q  +  ++        S P+               N  L+    D  V+
Sbjct: 18288 TEFTVSGLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARDEIDAPNASLDPKYKDVIVV 18347

Query: 1192  TVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNL---------SPGLE 1242
                       DI G  I     + + G  LEE     +   T             + G +
Sbjct: 18348 HAGETFVLEADIRGKPIPDVVWS-KDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQ 18406

Query: 1243  YNVSVYTVKDDKESVPISDTIIPEV-PQLTDLSFVDITDSSIGLRWTP--LNSSTIIGYR 1299
             Y + +  V   K S+PI+  ++    P    L    +T     L W P   +    I + 
Sbjct: 18407 YILKLSNVGGTK-SIPITVKVLDRPGPPEGPLKVTGVTAEKCYLAWNPPLQDGGANISHY 18465

Query: 1300  ITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGG-----ESAPTTLTQ 1354
             I        +   +   +     Y VT L PG +Y   V+ +   G     ES P T   
Sbjct: 18466 IIEKRETSRLSWTQVSTEVQALNYKVTKLLPGNEYIFRVMAVNKYGIGEPLESGPVTACN 18525

Query: 1355  QTAVP-PPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISP---S 1410
                 P PP+    + I  D+M VTWA P     T         +++E V     +    +
Sbjct: 18526 PYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDKEGVRWTKCNKKTLT 18585

Query: 1411  DNAVVLTNLLPGTEYVVSVSS-----VYEQHESTPLRGRQKTGL---DSPTGIDFSDITA 1462
             D  + +T L  G  Y   V++     V E  E +    R    L     P+    +D + 
Sbjct: 18586 DLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFY-RACDALYPPGPPSNPKVTDTSR 18644

Query: 1463  NSFTVHWIAP----RATITGYRIRHHPEHFSGRPREDRVPHS---RNSITLTNLTPGTEY 1515
             +S ++ W  P     A + GY +    +  +        P +       T+T L   TEY
Sbjct: 18645 SSVSLAWSKPIYDGGAPVKGYVV--EVKEAAADEWTTCTPPTGLQGKQFTVTKLKENTEY 18702

Query: 1516  VVSIVALN--GREESPLLIGQQSTVSDV-PRDLEVVAATPTSLLISWDAPAVTVRYYRIT 1572
                I A+N  G  E   L G       + P ++E+ A     +++   A   T+R +   
Sbjct: 18703 NFRICAINSEGVGEPATLPGSVVAQERIEPPEIELDADLRKVVVLRASA---TLRLFVTI 18759

Query: 1573  YGETGGNSPVQEFTVPGSKSTAT-ISGLKPGVDYTITVYAVTGRGDS---------PASS 1622
              G      P  E     ++   T  + ++    +T+ V     R DS          + S
Sbjct: 18760 KGR-----PEPEVKWEKAEGILTDRAQIEVTSSFTMLVIDNVTRFDSGRYNLTLENNSGS 18814

Query: 1623  KPISINYRTEIDKPS---QMQVTDVQDNSISVKWLP----SSSPVTGYRV---TTTPKNG 1672
             K   +N R  +D PS    + + +V+ +S+++ W P      + +T Y V    TT K  
Sbjct: 18815 KTAFVNVRV-LDSPSAPVNLTIREVKKDSVTLSWEPPLIDGGAKITNYIVEKRETTRK-- 18871

Query: 1673  PGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPK----G 1728
                  T T    +T   IE LQ    Y   V A N  G   P   T    +  P      
Sbjct: 18872 --AYATITNNCTKTTFRIENLQEGCSYYFRVLASNEYGIGLPAETTEPVKVSEPPLPPGR 18929

Query: 1729  LAFTDVDVDSIKIAWESPQ----GQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLR 1784
             +   DV  ++  I WE P+     +++ Y V   +   G  +       +   A + GL 
Sbjct: 18930 VTLVDVTRNTATIKWEKPESDGGSKITGYVVEMQT--KGSEKWSTCTQVKTLEATISGLT 18987

Query: 1785  PGSEYTVSVVALHDDMESQPL-----IGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQ 1839
              G EY   V A+++   S P      +  +   I    +L F   T    + +    +V 
Sbjct: 18988 AGEEYVFRVAAVNEKGRSDPRQLGVPVIARDIEIKPSVELPFH--TFNVKAREQLKIDVP 19045

Query: 1840  LTGYRVRVTPKEKTG-PMKEINLAPDSSSVVVSGLMV--ATKYEVSVYAL--KDTLTSRP 1894
               G         K G  +KE      SSS  V+ L +  A+K +V  Y L   ++  S  
Sbjct: 19046 FKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSNSAGSIT 19105

Query: 1895  AQGVVTTLENVSPPRRARVTDATETTITISWRTKTE----TITGFQVDAVPANGQT---- 1946
                 +  L+   PP   R+ + +  +ITISW          I+ + V+       T    
Sbjct: 19106 VPITIIVLDRPGPPGPIRIDEVSCDSITISWNPPEYDGGCQISNYIVEKKETTSTTWHIV 19165

Query: 1947  --PIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDA-------- 1996
                + RT      S  I  L  G++Y+  +   N   +SS      S+A+ A        
Sbjct: 19166 SQAVART------SIKIVRLTTGSEYQFRVCAENRYGKSS---YSESSAVVAEYPFSPPG 19216

Query: 1997  -PSNLRFLATTPNSLLVSWQPP----RARITGYIIKYEKPGSPPREVVPRPRPGVTEATI 2051
              P   + +  T +++LV+WQ P     +R+ GY ++Y++  S       +     T+  +
Sbjct: 19217 PPGTPKVVHATKSTMLVTWQVPVNDGGSRVIGYHLEYKERSSILWSKANKILIADTQMKV 19276

Query: 2052  TGLEPGT--EYTIY 2063
             +GL+ G   EY +Y
Sbjct: 19277 SGLDEGLMYEYRVY 19290



 Score =  109 bits (273), Expect = 3e-23
 Identities = 290/1404 (20%), Positives = 524/1404 (37%), Gaps = 190/1404 (13%)

Query: 812   DAPPDPT----VDQVDDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETAN 863
             D P  PT    +  + + S+ ++W  P+    + +T Y ++   +     TE++      
Sbjct: 20196 DRPGPPTGPVVISDITEESVTLKWEPPKYDGGSQVTNYILLKRETSTAVWTEVSATVART 20255

Query: 864   SVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFV-EVTDVK 922
              + +  L  G +Y   I A  EN+      I           T P P    +V  VT   
Sbjct: 20256 MMKVMKLTTGEEYQFRIKA--ENRFGISDHIDSACVTVKLPYTTPGPPSTPWVTNVTRES 20313

Query: 923   VTIMWTPPES----AVTGYRVDVIPVN-LPGEHGQRLPISRNTFAEVTGLSPGVTYYFKV 977
             +T+ W  P S    AV GY +++   N +  +   +L I R T  +VT +S G+ Y F+V
Sbjct: 20314 ITVGWHEPVSNGGSAVVGYHLEMKDRNSILWQKANKLVI-RTTHFKVTTISAGLIYEFRV 20372

Query: 978   FAVSHGRESKPL-TAQQTTKLDA---PTNLQFVNETDSTVLVRWTPPR----AQITGYRL 1029
             +A +     KP   ++    +DA   P N++  + + ++V + W  P     ++ITGY  
Sbjct: 20373 YAENAAGVGKPSHPSEPVLAIDACEPPRNVRITDISKNSVSLSWQQPAFDGGSKITGYI- 20431

Query: 1030  TVGLTRRGQP-----RQYNVGPSVSKYPLRNLQPASEYTVSLVA--IKGNQESP-KATGV 1081
                + RR  P     +      + +++ +  L   S+Y   + A    G+  +P +  G 
Sbjct: 20432 ---VERRDLPDGRWTKASFTNVTETQFIISGLTQNSQYEFRVFARNAVGSISNPSEVVGP 20488

Query: 1082  FTTLQ----PGSSIPPYNTEVTE----TTIV----ITWTPAPRI-GFKLGVRPSQGGEAP 1128
              T +     P   +P   TEV +    T++     I+  PAP I  +K            
Sbjct: 20489 ITCIDSYGGPVIDLPLEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVC 20548

Query: 1129  REVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDT 1188
              E T+D  SI++          Y +++        A I  +++    PP           
Sbjct: 20549 VENTTDLASILIKDADRLNSGCYELKLRNAMGSASATIRVQILDKPGPPGGPIEFKTVTA 20608

Query: 1189  GVLTVSWERSTTPD----ITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYN 1244
               +T+ W R    D    IT Y +    T+    + + E  H ++   T   +  G EY 
Sbjct: 20609 EKITLLW-RPPADDGGAKITHYIVEKRETSRVVWSMVSE--HLEECIITTTKIIKGNEYI 20665

Query: 1245  VSVYTVKDDKESVPI-SDTII----------PEVPQLTDLSFVDITDSSIGLRWT-PL-- 1290
               V  V       P+ SD+++          P +P++T      IT +S+ + W+ P+  
Sbjct: 20666 FRVRAVNKYGIGEPLESDSVVAKNAFVTPGPPGIPEVT-----KITKNSMTVVWSRPIAD 20720

Query: 1291  NSSTIIGYRITVVAAGEGIPIFEDFVDSSVGYY------------TVTGLEPGIDYDISV 1338
               S I GY              E     S+G++             VTGL    DY   V
Sbjct: 20721 GGSDISGY------------FLEKRDKKSLGWFKVLKETIRDTRQKVTGLTENSDYQYRV 20768

Query: 1339  ITLINGGE---SAPTTLTQQTAVP-----PPTDLRFTNIGPDTMRVTWAPP---PSIDLT 1387
               +   G+   S P+    + A P     PP  +R  +    ++ + W+ P       +T
Sbjct: 20769 CAVNAAGQGPFSEPSEF-YKAADPIDPPGPPAKIRIADSTKSSITLGWSKPVYDGGSAVT 20827

Query: 1388  NFLVRYSPVKNEE-DVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQ- 1445
              ++V     + EE               V++NL PG  Y   VS+V    +  P+   + 
Sbjct: 20828 GYVVEIRQGEEEEWTTVSTKGEVRTTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEP 20887

Query: 1446  ---KTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRN 1502
                K  L++P  ID       S           +  ++ R  P     +  ++    +R 
Sbjct: 20888 VQAKDILEAPE-IDLDVALRTSVIAKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARY 20946

Query: 1503  SI---------TLTNLTPGT--EYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAAT 1551
             SI         T+  +T     +Y+++I    G  +S  +  +        + L+V   +
Sbjct: 20947 SIENTDSSSLLTIPQVTRNDTGKYILTIENGVGEPKSSTVSVKVLDTPAACQKLQVKHVS 21006

Query: 1552  PTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGL-----KPGVDYT 1606
               ++ + WD P +      I Y     ++  + ++V   K ++T   L     K    + 
Sbjct: 21007 RGTVTLLWDPPLIDGGSPIINYVIEKRDATKRTWSVVSHKCSSTSFKLIDLSEKTPFFFR 21066

Query: 1607  ITVYAVTGRGDSPASSKPISINYRTEIDKP-SQMQVTDVQDNSISVKW----LPSSSPVT 1661
             +      G G+   +++P+      E+  P   + + D    S+ + W        S +T
Sbjct: 21067 VLAENEIGIGEPCETTEPVK---AAEVPAPIRDLSMKDSTKTSVILSWTKPDFDGGSVIT 21123

Query: 1662  GYRVTTTPKNGPGPTKTKTAGPDQT-EMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAV 1720
              Y V    + G G      AG  +T E+ +  L+        V+A+N  G S P+    +
Sbjct: 21124 EYVV---ERKGKGEQTWSHAGISKTCEIEVSQLKEQSVLEFRVFAKNEKGLSDPVTIGPI 21180

Query: 1721  TNIDRPKGLAFT-DVDVDSIKIAWESPQ-GQVSRYRVTY-SSPEDGIHEL---FPAPDGE 1774
             T     K L  T +VD+  I  A  + + G      + Y   P+  I  L    P  + E
Sbjct: 21181 T----VKELIITPEVDLSDIPGAQVTVRIGHNVHLELPYKGKPKPSISWLKDGLPLKESE 21236

Query: 1775  -------EDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPT----DLKFTQ 1823
                    E+   L       E+      + D+   +  +      +  P+     ++F +
Sbjct: 21237 FVRFSKTENKITLSIKNAKKEHGGKYTVILDNAVCRIAVPITVITLGPPSKPKGPIRFDE 21296

Query: 1824  VTPTSLSAQWTPP----NVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKY 1879
             +   S+   W  P      ++T Y +      +T   K +  +   ++  V  L+   +Y
Sbjct: 21297 IKADSVILSWDVPEDNGGGEITCYSIEKRETSQTN-WKMVCSSVARTTFKVPNLVKDAEY 21355

Query: 1880  EVSVYALKDTLTSRPAQGVVTTLEN----VSPPRRARVTDATETTITISWRTKT----ET 1931
             +  V A      S+P    +   ++      PP +  + + T   ++++W          
Sbjct: 21356 QFRVRAENRYGVSQPLVSSIIVAKHQFRIPGPPGKPVIYNVTSDGMSLTWDAPVYDGGSE 21415

Query: 1932  ITGFQVDAVPANGQTPIQRTIKP-DVRSYTITGLQPGTDYKIYLYTLNDNARSSP----V 1986
             +TGF V+    N     +    P   R Y  TGL  G DY+  +Y  N    SSP     
Sbjct: 21416 VTGFHVEKKERNSILWQKVNTSPISGREYRATGLVEGLDYQFRVYAENSAGLSSPSDPSK 21475

Query: 1987  VIDASTAIDAPSNLRFLATTPNSLLVSWQPP----RARITGYIIKYEKPGSPPREVVPRP 2042
                A + +D P    ++  T  ++ + W PP     ++I GY I+ ++ G+         
Sbjct: 21476 FTLAVSPVDPPGTPDYIDVTRETITLKWNPPLRDGGSKIVGYSIE-KRQGNERWVRCNFT 21534

Query: 2043  RPGVTEATITGLEPGTEYTIYVIA 2066
                  + T+TGL PG  Y   +IA
Sbjct: 21535 DVSECQYTVTGLSPGDRYEFRIIA 21558



 Score =  109 bits (272), Expect = 4e-23
 Identities = 299/1423 (21%), Positives = 501/1423 (35%), Gaps = 243/1423 (17%)

Query: 728   VTEITASSFVVSW----VSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPG 783
             +++I A +  +SW          ++ + VE      GD    L    T TS  +  L+PG
Sbjct: 12629 ISDIDADACSLSWHIPLEDGGSNITNYIVEKCDVSRGDWVTAL-ASVTKTSCRVGKLIPG 12687

Query: 784   RKYIVNV-----YQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ--- 835
             ++YI  V     + ISE      +++      P  P +  V +V+   I V W RP    
Sbjct: 12688 QEYIFRVRAENRFGISEPLTSPKMVAQFPFGVPSEPKNARVTKVNKDCIFVAWDRPDSDG 12747

Query: 836   -APITGYRIVYSPS-----VEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQES 889
              +PI GY I          V+ + T +   E       + L  G++Y+  IYA+ +   S
Sbjct: 12748 GSPIIGYLIERKERNSLLWVKANDTLVRSTE----YPCAGLVEGLEYSFRIYALNKAGSS 12803

Query: 890   TPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPVN 945
              P    +  T     D    P   + ++VT   V+++W  P+    S + GY V+     
Sbjct: 12804 PPSKPTEYVTARMPVDPPGKP---EVIDVTKSTVSLIWARPKHDGGSKIIGYFVEA--CK 12858

Query: 946   LPGEHGQRLPISRNTFAE----VTGLSPGVTYYFKVF---AVSHGRESKPLTAQQTTKLD 998
             LPG+   R   + +   +     TGL     Y F+     AV+    S+P         +
Sbjct: 12859 LPGDKWVRCNTAPHQIPQEEYTATGLEEKAQYQFRAIARTAVNISPPSEPSDPVTILAEN 12918

Query: 999   APTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQ----------YNVGPSV 1048
              P  +       S + V+         G  + +  T  G+P                  +
Sbjct: 12919 VPPRIDLSVAMKSLLTVK--------AGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGI 12970

Query: 1049  SKYPLRNL----------QPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEV 1098
                  RNL          + + +YT++     G++ +     V    +PG   PP + ++
Sbjct: 12971 KMAMQRNLCTLELFSVNRKDSGDYTITAENSSGSKSATIKLKVLD--KPG---PPASVKI 13025

Query: 1099  TE---TTIVITWTPAPRIG------FKLGVR-PSQGGEAPREVTSDSGSIVVSGLTPGVE 1148
              +      +++W P    G      + +  R  S+   A    T    S  V  L  G E
Sbjct: 13026 NKMYSDRAMLSWEPPLEDGGSEITNYIVDKRETSRPNWAQVSATVPITSCSVEKLIEGHE 13085

Query: 1149  YVYTIQVLRDGQERDAPIVNKVV--TPLSPPTNLH--LEANPDTGVLTVSWERSTT---P 1201
             Y + I         D       +   P  PP      + +N     +TVSW+        
Sbjct: 13086 YQFRICAENKYGVGDPVFTEPAIAKNPYDPPGRCDPPVISNITKDHMTVSWKPPADDGGS 13145

Query: 1202  DITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTV--------KDD 1253
              ITGY +    T       +      ++ +     L  G EY   V  +         D 
Sbjct: 13146 PITGYLLEKRETQAVNWTKVNRKPIIER-TLKATGLQEGTEYEFRVTAINKAGPGKPSDA 13204

Query: 1254  KESVPISDTIIPEVPQLTDLSFVDITDSSIGLRWTPL---NSSTIIGYRITVVAAGEGIP 1310
              ++    D   P  P      + D T SS+ L W        S IIGY + V  A     
Sbjct: 13205 SKAAYARDPQYPPGPPAFPKVY-DTTRSSVSLSWGKPAYDGGSPIIGYLVEVKRADS--- 13260

Query: 1311  IFEDFVDSSVGY------YTVTGLEPGIDYDISVITLINGGESAPTTL-----TQQTAVP 1359
               +++V  ++        + VTGL     Y   V  +   G S P+ +      +   +P
Sbjct: 13261 --DNWVRCNLPQNLQKTRFEVTGLMEDTQYQFRVYAVNKIGYSDPSDVPDKHYPKDILIP 13318

Query: 1360  P----PTDLRFTNI--GPDTMR----VTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISP 1409
             P      DLR T I     TMR    V   PPP I  +       P  N  D   L I  
Sbjct: 13319 PEGELDADLRKTLILRAGVTMRLYVPVKGRPPPKITWS------KPNVNLRDRIGLDIKS 13372

Query: 1410  SDNAVVL----TNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSF 1465
             +D    L     N     +Y++++ +   + E T +     T    P  +   +I+ +S 
Sbjct: 13373 TDFDTFLRCENVNKYDAGKYILTLENSCGKKEYTIVVKVLDTP-GPPVNVTVKEISKDSA 13431

Query: 1466  TVHWIAP----RATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVA 1521
              V W  P     + I  Y ++                 S+ S  + NL  G  Y   + A
Sbjct: 13432 YVTWEPPIIDGGSPIINYVVQKRDAERKSWSTV-TTECSKTSFRVANLEEGKSYFFRVFA 13490

Query: 1522  LNGREESPLLIGQQSTVSDVPR---------DLEVVAATPTSLLISWDAPAVTVRYYRIT 1572
                  E+   IG      D  +         DL+V + + +S  I W  P        I 
Sbjct: 13491 -----ENEYGIGDPGETRDAVKASQTPGPVVDLKVRSVSKSSCSIGWKKPHSDGGSRIIG 13545

Query: 1573  YGETGGNSPVQEFTVPGSKSTATISGLK---------PGVDYTITVYAVTGRGDSPASSK 1623
             Y        V +F    +K    +  L           G +YT  V A    G+   S  
Sbjct: 13546 Y--------VVDFLTEENKWQRVMKSLSLQYSAKDLTEGKEYTFRVSAENENGEGTPSE- 13596

Query: 1624  PISINYRTEIDKPSQMQVTDVQDNSISVKWLPS----SSPVTGYRVTTTPKNGPGPTKTK 1679
              I++  R ++  P            + +K LP     +   + +R+    K  P P+ + 
Sbjct: 13597 -ITVVARDDVVAP-----------DLDLKGLPDLCYLAKENSNFRLKIPIKGKPAPSVSW 13644

Query: 1680  TAGPD----QTEMTIEGLQPTVEYVV-----------SVYAQNPSGESQPLVQTAVTNID 1724
               G D     T +++E        +V           ++  +N +G  +  +   V    
Sbjct: 13645 KKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKEGTISIKVVGKP 13704

Query: 1725  R-PKG-LAFTDVDVDSIKIAWESPQGQVSRYRVTY-SSPEDGIHELFP--APDGEEDTAE 1779
               P G + F +V  +++ + W  P+         Y     D ++  +   A   ++ T  
Sbjct: 13705 GIPTGPIKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDSVNNKWVTCASAVQKTTFR 13764

Query: 1780  LQGLRPGSEYTVSVVA-----LHDDMESQPLIGTQSTAIP-APTDLKFTQVTPTSLSAQW 1833
             +  L  G EYT  V A     + + ++S+P++      +P AP       V   S+S  W
Sbjct: 13765 VTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVPDAPPPPNIVDVRHDSVSLTW 13824

Query: 1834  TPP----NVQLTGYRVRVTPKEKTGPM-KEINLAP-DSSSVVVSGLMVATKYEVSVYAL- 1886
             T P       +TGY +    KE+   + K  N  P       V+GL    +YE  V A+ 
Sbjct: 13825 TDPKKTGGSPITGYHLEF--KERNSLLWKRANKTPIRMRDFKVTGLTEGLEYEFRVMAIN 13882

Query: 1887  -----KDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKT----ETITGFQV 1937
                  K +L S P    V  L+ + PP +  V + T  ++T+ W          +TG+ V
Sbjct: 13883 LAGVGKPSLPSEP----VVALDPIDPPGKPEVINITRNSVTLIWTEPKYDGGHKLTGYIV 13938

Query: 1938  DA--VPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLN 1978
             +   +P+           P+  ++T+T L  G  Y+  +   N
Sbjct: 13939 EKRDLPSKSWMKANHVNVPEC-AFTVTDLVEGGKYEFRIRAKN 13980



 Score =  108 bits (269), Expect = 8e-23
 Identities = 265/1341 (19%), Positives = 468/1341 (34%), Gaps = 163/1341 (12%)

Query: 780   LLPGRKYIVNVYQISEDGE----QSLILSTSQTTAPDAPPD-PTVDQVDDTSIVVRWSRP 834
             L+ G +YI  V  ++  G+    QS  +       P  PP+ P V  V   +  V W RP
Sbjct: 14164 LIQGNEYIFRVSAVNHYGKGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSWKRP 14223

Query: 835   Q----APITGYRIVYSPSVEGSSTE-LNLPETANSVTLSDLQPGVQYNITIYA-----VE 884
                  + ITGY +             +  P +     ++ LQ G  Y   + A     + 
Sbjct: 14224 VDDGGSEITGYHVERREKKSLRWVRAIKTPVSDLRCKVTGLQEGSTYEFRVSAENRAGIG 14283

Query: 885   ENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPES----AVTGYRVD 940
                E++  V+ ++    P   + P   D      T    ++ W  P       +TGY V+
Sbjct: 14284 PPSEASDSVLMKDAAYPPGPPSNPHVTD-----TTKKSASLAWGKPHYDGGLEITGYVVE 14338

Query: 941   VIPVN----LPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQ--QT 994
                V     +    G  L I++     V  L     Y F++ A++     +P      + 
Sbjct: 14339 HQKVGDEAWIKDTTGTALRITQFV---VPDLQTKEKYNFRISAINDAGVGEPAVIPDVEI 14395

Query: 995   TKLDAPTNLQFVNETDSTVLVR-------WTP----PRAQITGYRLTVGLTRRGQPRQYN 1043
              + +   + +   E   T++VR       + P    P  ++T  +  + L  R       
Sbjct: 14396 VEREMAPDFELDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKNRANIENTE 14455

Query: 1044  VGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTI 1103
                ++   P  N     ++ +++    G +       V  T  P  ++ P  T++T+ ++
Sbjct: 14456 -SFTLLIIPECNRYDTGKFVMTIENPAGKKSGFVNVRVLDTPGPVLNLRP--TDITKDSV 14512

Query: 1104  VITWT-PAPRIGFKLGVRPSQGGEAPREVTSDSGS------IVVSGLTPGVEYVYTIQVL 1156
              + W  P    G ++     +  EA R+  S + +        V+GL+ G EY + +   
Sbjct: 14513 TLHWDLPLIDGGSRITNYIVEKREATRKSYSTATTKCHKCTYKVTGLSEGCEYFFRVMAE 14572

Query: 1157  RD---GQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPD---ITGYRITT 1210
              +   G+  +     K     SPP +L++  +     ++++W +        ITGY I  
Sbjct: 14573 NEYGIGEPTETTEPVKASEAPSPPDSLNI-MDITKSTVSLAWPKPKHDGGSKITGYVIEA 14631

Query: 1211  TPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISD--TIIPEVP 1268
                   Q   +  V   +   C   NL+ G EY   V  V     S P      I+ E  
Sbjct: 14632 QRKGSDQWTHITTVKGLE---CVVRNLTEGEEYTFQVMAVNSAGRSAPRESRPVIVKEQT 14688

Query: 1269  QLTDLSFVDITDSSIGLRWTPLNSSTI--IGYRITVVAAGEGIPI--------FEDFVDS 1318
              L +L    I    +  +        I  +G     V   +G  I        FE    S
Sbjct: 14689 MLPELDLRGIYQKLVIAKAGDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATS 14748

Query: 1319  SVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTW 1378
             ++             Y ++   ++       T        PP   ++F  +  D +  +W
Sbjct: 14749 TILNINECVRSDSGPYPLTARNIVGEVGDVITIQVHDIPGPPTGPIKFDEVSSDFVTFSW 14808

Query: 1379  APPPS---IDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSS---- 1431
              PP +   + ++N++V      +   V EL+ +        T L  G EY   V +    
Sbjct: 14809 DPPENDGGVPISNYVVEMRQTDSTTWV-ELATTVIRTTYKATRLTTGLEYQFRVKAQNRY 14867

Query: 1432  -VYEQHESTPLRGRQKTGLDSPTGI-DFSDITANSFTVHWIAP----RATITGYRIRHHP 1485
              V     S  +       +  P G    + +T +S T+ W  P     + I GY +    
Sbjct: 14868 GVGPGITSACIVANYPFKVPGPPGTPQVTAVTKDSMTISWHEPLSDGGSPILGYHVERKE 14927

Query: 1486  EHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN-------GREESPLLIGQQSTV 1538
              +        +     N    + LT G  Y   ++A N        +   P+L       
Sbjct: 14928 RNGILWQTVSKALVPGNIFKSSGLTDGIAYEFRVIAENMAGKSKPSKPSEPMLALDPIDP 14987

Query: 1539  SDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPG----SKSTA 1594
                P  L +   T T   + W  P  T  +   +Y     + P   +         ++  
Sbjct: 14988 PGKPVPLNITRHTVT---LKWAKPEYTGGFKITSYIVEKRDLPNGRWLKANFSNILENEF 15044

Query: 1595  TISGLKPGVDYTITVYAVTGRGD-SPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKW 1653
             T+SGL     Y   V A    G  SP S    +I  R +++ P        +D  I    
Sbjct: 15045 TVSGLTEDAAYEFRVIAKNAAGAISPPSEPSDAITCRDDVEAPKIKVDVKFKDTVI---- 15100

Query: 1654  LPSSSPVTGYRVTTTPKNGPGPTK------TKTAGPDQTEMTIEGLQPTV---------E 1698
                      +R+       P PT        +  G  + E+ I      +          
Sbjct: 15101 ---LKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDS 15157

Query: 1699  YVVSVYAQNPSGESQPLVQTAVTNIDRP----KGLAFTDVDVDSIKIAWESP---QGQVS 1751
                ++ A NP G ++ +    V  +DRP      LA T+V  +   ++W  P    G   
Sbjct: 15158 GAYTLTATNPGGFAKHIFNVKV--LDRPGPPEGPLAVTEVTSEKCVLSWFPPLDDGGAKI 15215

Query: 1752  RYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALH-----DDMESQPLI 1806
              + +        +     A + +    ++  L  G+EY   V+A++     + +ES+P++
Sbjct: 15216 DHYIVQKRETSRLAWTNVASEVQVTKLKVTKLLKGNEYIFRVMAVNKYGVGEPLESEPVL 15275

Query: 1807  GTQSTAIP-APTDLKFTQVTPTSLSAQWTPPN----VQLTGYRVRVTPKEKTGPMKEINL 1861
                    P  P + + T +T  S+   W  P+     ++  Y V    K     +K    
Sbjct: 15276 AVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEIINYIVERRDKAGQRWIKCNKK 15335

Query: 1862  APDSSSVVVSGLMVATKYEVSVYA-----LKDTLTSRPAQGVVTTLENVSPPRRARVTDA 1916
                     VSGL    +YE  + A     +     + P      T+    PP   RV D 
Sbjct: 15336 TLTDLRYKVSGLTEGHEYEFRIMAENAAGISAPSPTSPFYKACDTVFKPGPPGNPRVLDT 15395

Query: 1917  TETTITISWRTKT----ETITGFQVD-AVPANGQTPIQRTIKP----DVRSYTITGLQPG 1967
             + ++I+I+W          ITG+ V+ A+P   +  I   + P       SYTITGL   
Sbjct: 15396 SRSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQI---VTPPAGLKATSYTITGLTEN 15452

Query: 1968  TDYKIYLYTLNDNARSSPVVI 1988
              +YKI +Y +N      P ++
Sbjct: 15453 QEYKIRIYAMNSEGLGEPALV 15473



 Score =  107 bits (268), Expect = 1e-22
 Identities = 324/1575 (20%), Positives = 574/1575 (36%), Gaps = 187/1575 (11%)

Query: 552   RWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCY-----GRGIGEWHCQPLQTYP 606
             RWK    D  +    G  Y++       + G  YQ   Y     G G       P     
Sbjct: 9990  RWKRVNRDPIKAMTLGVSYKVTG----LIEGSDYQFRVYAINAAGVGPASLPSDPATARD 10045

Query: 607   SSSGPVEVFITETPSQPNSHPIQWNAPQP---SHISKYILRWRP--KNSVGRWKEATIPG 661
               + P   F   T    +S  ++W+ P     S ++ YI+ ++   K    + K+  + G
Sbjct: 10046 PIAPPGPPFPKVTDWTKSSADLEWSPPLKDGGSKVTGYIVEYKEEGKEEWEKGKDKEVRG 10105

Query: 662   HLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPL 721
                   + GLK G  Y+ ++ ++   G  E              + S  +  + +    +
Sbjct: 10106 --TKLVVTGLKEGAFYKFRVRAVNIAGIGEPGEVT-DVIEMKDRLVSPDLQLDASVRDRI 10162

Query: 722   VATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTA--TSVNIPD 779
             V  +  V  I      +++VS     +   V + ++E    PQ   + +TA  +S+ I +
Sbjct: 10163 VVHAGGVIRI------IAYVSGKPPPT---VTWNMNER-TLPQEATIETTAISSSMVIKN 10212

Query: 780   LLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTV-DQVDDTSIVVRWSRPQ--- 835
                  + + ++   +E GE+   +       P     P +   + + S  + W  P+   
Sbjct: 10213 CQRSHQGVYSLLAKNEAGERKKTIIVDVLDVPGPVGTPFLAHNLTNESCKLTWFSPEDDG 10272

Query: 836   -APITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVI 894
              +PIT Y I    S   + T +    T  + T+  L  G  Y   I A E +    P V 
Sbjct: 10273 GSPITNYVIEKRESDRRAWTPVTYTVTRQNATVQGLIQGKAYFFRI-AAENSIGMGPFVE 10331

Query: 895   QQETTGTPRSDTVPS-PRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPVNLPGE 949
               E        TVP  P DL+  EVT   VT+ W PP+    S +  Y   V+   L G 
Sbjct: 10332 TSEALVIREPITVPERPEDLEVKEVTKNTVTLTWNPPKYDGGSEIINY---VLESRLIGT 10388

Query: 950   HGQRLPISRNTFAE---VTGLSPGVTYYFKVFAVS---HGRES---KPLT-----AQQTT 995
                    + N  +    V GL  G TY ++V AV+    G+ S   KP+T     A  T 
Sbjct: 10389 EKFHKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGKPSFCTKPITCKDELAPPTL 10448

Query: 996   KLDAPTNLQF-VNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLR 1054
              LD    L   V E  +        P+ +++ ++    +    +        +++   ++
Sbjct: 10449 HLDFRDKLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATLALEKIK 10508

Query: 1055  -NLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYN-TEVTETTIVITWTP--- 1109
                  + +Y V +    G+++      V    +PG  + P +  EVT+  +VI+W P   
Sbjct: 10509 AKRSDSGKYCVVVENSTGSRKGFCQVNVVD--RPGPPVGPVSFDEVTKDYMVISWKPPLD 10566

Query: 1110  --APRIGFKLGVRPSQGGEAPREVTSDSGSIV--VSGLTPGVEYVYTIQV-----LRDGQ 1160
                 +I   +  +   G +    VTS S      VS L  G +Y++ I       + D  
Sbjct: 10567 DGGSKITNYIIEKKEVGKDVWMPVTSASAKTTCKVSKLLEGKDYIFRIHAENLYGISDPL 10626

Query: 1161  ERDA-PIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGN 1219
               D+    ++   P +P   +  E   D+ ++T +        IT Y +    T  ++  
Sbjct: 10627 VSDSMKAKDRFRVPDAPDQPIVTEVTKDSALVTWNKPHDGGKPITNYILEKRETMSKRWA 10686

Query: 1220  SLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKD------DKESVPI--SDTIIPEVPQLT 1271
              + +      +     +L  G +Y   V    +         S P+   D I    P + 
Sbjct: 10687 RVTKDPIHPYTKFRVPDLLEGCQYEFRVSAENEIGIGDPSPPSKPVFAKDPIAKPSPPVN 10746

Query: 1272  DLSFVDITDSSIGLRWTPL---NSSTIIGYRITVVAAGEGIPIFEDFVDSSV--GYYTVT 1326
                 +D T +S+ L W P      S I+GY +     G+      +    S     Y VT
Sbjct: 10747 P-EAIDTTCNSVDLTWQPPRHDGGSKILGYIVEYQKVGDEEWRRANHTPESCPETKYKVT 10805

Query: 1327  GLEPGIDYDISVITLINGGESAPTTLTQQTAV----PPPTDLRFTNIG-------PDTMR 1375
             GL  G  Y   V+ +   GES P  + +   V     PP  +   N+         DT+R
Sbjct: 10806 GLRDGQTYKFRVLAVNAAGESDPAHVPEPVLVKDRLEPPELILDANMAREQHIKVGDTLR 10865

Query: 1376  ----VTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLL--PGTEYVVSV 1429
                 +   P P +       R +P K     A + ++P  + + + N     G  Y ++V
Sbjct: 10866 LSAIIKGVPFPKVTWKK-EDRDAPTK-----ARIDVTPVGSKLEIRNAAHEDGGIYSLTV 10919

Query: 1430  SS-VYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAP----RATITGYRIRHH 1484
              +    +  S  +    K G   P  ++ S+I  +S  + W  P     + IT Y +   
Sbjct: 10920 ENPAGSKTVSVKVLVLDKPG--PPRDLEVSEIRKDSCYLTWKEPLDDGGSVITNYVVERR 10977

Query: 1485  PEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVS----- 1539
              +  S +         + S    +L  G +Y+  + A N     P +   +   +     
Sbjct: 10978 -DVASAQWSPLSATSKKKSHFAKHLNEGNQYLFRVAAENQYGRGPFVETPKPIKALDPLH 11036

Query: 1540  --DVPRDLEVVAATPTSLLISWDAP----AVTVRYYRITYGETGGNSPVQEFTVPGSKST 1593
                 P+DL  V    T + + W+ P       +  Y + Y E G    ++  TV  +   
Sbjct: 11037 PPGPPKDLHHVDVDKTEVSLVWNKPDRDGGSPITGYLVEYQEEGTQDWIKFKTV--TNLE 11094

Query: 1594  ATISGLKPGVDYTITVYA--VTGRGDSPASSKPISINYR-----TEIDKPSQMQVTDVQD 1646
               ++GL+ G  Y   V A  + G G  P ++ PI    +      E+D      +     
Sbjct: 11095 CVVTGLQQGKTYRFRVKAENIVGLG-LPDTTIPIECQEKLVPPSVELDVKLIEGLVVKAG 11153

Query: 1647  NSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTE-----MTIEGL--QPTVEY 1699
              ++    +    PV   + TT         KT      +T+     +TI+    + T EY
Sbjct: 11154 TTVRFPAIIRGVPVPTAKWTTDGSE----IKTDEHYTVETDNFSSVLTIKNCLRRDTGEY 11209

Query: 1700  VVSVYAQNPSGESQPLVQTAVTNIDRPK--GLAFTDVDVDSIKIAWESPQGQVSRYRVTY 1757
              ++V   N +G     V   V ++  P    +   DV  + + I+W+ P+       + Y
Sbjct: 11210 QITV--SNAAGSKTVAVHLTVLDVPGPPTGPINILDVTPEHMTISWQPPKDDGGSPVINY 11267

Query: 1758  -SSPEDGIHELFPAPDGEEDTAELQ--GLRPGSEYTVSV-----VALHDDMESQPLIGTQ 1809
                 +D   + +          +L+   L+ G EY   V     + +   ++S P +   
Sbjct: 11268 IVEKQDTRKDTWGVVSSGSSKTKLKIPHLQKGCEYVFRVRAENKIGVGPPLDSTPTVAKH 11327

Query: 1810  STAIPAPTDLK-FTQVTPTSLSAQWTPPNVQ----LTGYRVRVTPKEKTGPMKEINLAPD 1864
               + P+P      T +T  + +  WT P       +TGY +    +E TG    +N  P 
Sbjct: 11328 KFSPPSPPGKPVVTDITENAATVSWTLPKSDGGSPITGYYME--RREVTGKWVRVNKTPI 11385

Query: 1865  SS-SVVVSGLMVATKYEVSVYALKDTLTSRPAQG-----VVTTLENVSPPRRARVTDATE 1918
             +     V+GL     YE  V+A      S+P+           ++   PP   ++ D + 
Sbjct: 11386 ADLKFRVTGLYEGNTYEFRVFAENLAGLSKPSPSSDPIKACRPIKPPGPPINPKLKDKSR 11445

Query: 1919  TTITISWRTKT-----ETITGFQVDAVPANGQTPIQRTIKPDV---RSYTITGLQPGTDY 1970
              T  + W TK        I G+ V+     G     R  K ++    ++ + GL  G +Y
Sbjct: 11446 ETADLVW-TKPLSDGGSPILGYVVEC-QKPGTAQWNRINKDELIRQCAFRVPGLIEGNEY 11503

Query: 1971  KIYLYTLNDNARSSP 1985
             +  +   N      P
Sbjct: 11504 RFRIKAANIVGEGEP 11518



 Score =  106 bits (265), Expect = 2e-22
 Identities = 320/1538 (20%), Positives = 543/1538 (35%), Gaps = 226/1538 (14%)

Query: 702   TSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSW----VSASDTVSGFRVEYELS 757
             T  P  S  V  +T    P       VT+++     V W         +++G+ +E    
Sbjct: 12006 TGPPTESKPVIAKTKYDKPGRPDPPEVTKVSKEEMTVVWNPPEYDGGKSITGYFLE---K 12062

Query: 758   EEGDEPQYLDLPSTATS---VNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDA- 813
             +E    +++ +  +A     + + +LLP  +Y   V   +E G     L +    A D  
Sbjct: 12063 KEKHSTRWVPVNKSAIPERRMKVQNLLPDHEYQFRVKAENEIGIGEPSLPSRPVVAKDPI 12122

Query: 814   --PPDPTVDQVDDT---SIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANS 864
               P  PT  +V DT   SI + W +P     API GY +   P +  +S +        +
Sbjct: 12123 EPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAPIIGYVVEMRPKIADASPDEGWKRCNAA 12182

Query: 865   VTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGT------------------PRSDT 906
               L      V+   T+ +++ENQE    V  Q   G                   P  D 
Sbjct: 12183 AQL------VRKEFTVTSLDENQEYEFRVCAQNQVGIGRPAELKEAIKPKEILEPPEIDL 12236

Query: 907   VPSPRDLQFVEV-TDVKV-TIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEV 964
               S R L  V     +++  I+   P   VT  +V +  V      GQ   +    F  +
Sbjct: 12237 DASMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVV---RKGQVDLVDTMAFLVI 12293

Query: 965   TGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAP-TNLQFVNETDSTVLVRWTPPR-- 1021
                +   +  + +  V+   E       +      P ++L+  + T ++  V W PP   
Sbjct: 12294 PNSTRDDSGKYSLTLVNPAGEKAVFVNVRVLDTPGPVSDLKVSDVTKTSCHVSWAPPEND 12353

Query: 1022  --AQITGYRLTVGLTRRGQPRQYNVGPSVSK--YPLRNLQPASEYTVSLVAIKGNQESPK 1077
               +Q+T Y   V      +     V P V K  + + NL P +EY   + A+  N+  P 
Sbjct: 12354 GGSQVTHY--IVEKREADRKTWSTVTPEVKKTSFHVTNLVPGNEYYFRVTAV--NEYGPG 12409

Query: 1078  ATG-----VFTTLQPGSSIPPYNTEVTETT---IVITWTPAPRIG-FKLG--VRPSQGGE 1126
                     V  +       PP   EVTE T     + W P  R G  K+   +   +  E
Sbjct: 12410 VPTDVPKPVLASDPLSEPDPPRKLEVTEMTKNSATLAWLPPLRDGGAKIDGYITSYREEE 12469

Query: 1127  APREVTSDSG-----SIVVSGLTPGVEYVYTI---QVLRDGQERDAPIVNKVVTPLSPPT 1178
              P +  ++       S+VV+GL  G +Y + +     +     R+A  V +    L PP 
Sbjct: 12470 QPADRWTEYSVVKDLSLVVTGLKEGKKYKFRVAARNAVGVSLPREAEGVYEAKEQLLPPK 12529

Query: 1179  NL-----------------HLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSL 1221
              L                 H+   P     T  W++     +T   +     +      +
Sbjct: 12530 ILMPEQITIKAGKKLRIEAHVYGKPHP---TCKWKKGEDEVVTSSHLAVHKADSSSILII 12586

Query: 1222  EEVVHADQS--SCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPEVPQLTDLSFVDIT 1279
             ++V   D    S T +N S               K  V + D   P  P   D+S  DI 
Sbjct: 12587 KDVTRKDSGYYSLTAENSSG----------TDTQKIKVVVMDAPGPPQPPF-DIS--DID 12633

Query: 1280  DSSIGLRW-TPLNS--STIIGYRITV--VAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDY 1334
               +  L W  PL    S I  Y +    V+ G+ +        +S     V  L PG +Y
Sbjct: 12634 ADACSLSWHIPLEDGGSNITNYIVEKCDVSRGDWVTALASVTKTSC---RVGKLIPGQEY 12690

Query: 1335  DISVITLINGGESAPTTLTQQTAVPP------PTDLRFTNIGPDTMRVTWAPPPSIDLTN 1388
                V      G S P T  +  A  P      P + R T +  D + V W  P S D  +
Sbjct: 12691 IFRVRAENRFGISEPLTSPKMVAQFPFGVPSEPKNARVTKVNKDCIFVAWDRPDS-DGGS 12749

Query: 1389  FLVRYSPVKNEEDVAELSISPSDNAVVLTN-----LLPGTEYVVSVSSVYEQHESTPLRG 1443
              ++ Y  ++ +E  + L +  +D  V  T      L+ G EY   + ++ +   S P + 
Sbjct: 12750 PIIGYL-IERKERNSLLWVKANDTLVRSTEYPCAGLVEGLEYSFRIYALNKAGSSPPSKP 12808

Query: 1444  RQ----KTGLDSPTGIDFSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPRED 1495
              +    +  +D P   +  D+T ++ ++ W  P+    + I GY +           R +
Sbjct: 12809 TEYVTARMPVDPPGKPEVIDVTKSTVSLIWARPKHDGGSKIIGYFVEACKLPGDKWVRCN 12868

Query: 1496  RVPHS--RNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTV---SDVPRDLEVVAA 1550
               PH   +   T T L    +Y    +A      SP             +VP  +++  A
Sbjct: 12869 TAPHQIPQEEYTATGLEEKAQYQFRAIARTAVNISPPSEPSDPVTILAENVPPRIDLSVA 12928

Query: 1551  TPTSLLIS------WDAPAVTVRYYRITYGETGGN-SPVQEFTVPGSKSTATIS----GL 1599
               + L +        DA         +++ + G    P +   +   ++  T+       
Sbjct: 12929 MKSLLTVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNR 12988

Query: 1600  KPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLP---- 1655
             K   DYTIT         S + S  I +    +   P+ +++  +  +   + W P    
Sbjct: 12989 KDSGDYTITA-----ENSSGSKSATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLED 13043

Query: 1656  SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPL 1715
               S +T Y V     + P   +     P  T  ++E L    EY   + A+N  G   P+
Sbjct: 13044 GGSEITNYIVDKRETSRPNWAQVSATVPI-TSCSVEKLIEGHEYQFRICAENKYGVGDPV 13102

Query: 1716  -VQTAVT-NIDRPKGLA----FTDVDVDSIKIAWESPQGQ----VSRYRVTYSSPEDGIH 1765
               + A+  N   P G       +++  D + ++W+ P       ++ Y +     +    
Sbjct: 13103 FTEPAIAKNPYDPPGRCDPPVISNITKDHMTVSWKPPADDGGSPITGYLLEKRETQAVNW 13162

Query: 1766  ELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAI------PAPTDL 1819
                      E T +  GL+ G+EY   V A++     +P   +++         P P   
Sbjct: 13163 TKVNRKPIIERTLKATGLQEGTEYEFRVTAINKAGPGKPSDASKAAYARDPQYPPGPPAF 13222

Query: 1820  -KFTQVTPTSLSAQWTPPNVQ----LTGYRVRVTPKEKTGPMKEINLAPD--SSSVVVSG 1872
              K    T +S+S  W  P       + GY V V   +    ++  NL  +   +   V+G
Sbjct: 13223 PKVYDTTRSSVSLSWGKPAYDGGSPIIGYLVEVKRADSDNWVR-CNLPQNLQKTRFEVTG 13281

Query: 1873  LMVATKYEVSVYALKDTLTSRPAQ--GVVTTLENVSPPRRARVTDATETTITISWRTKTE 1930
             LM  T+Y+  VYA+     S P+         + + PP      D  +T I  +  T   
Sbjct: 13282 LMEDTQYQFRVYAVNKIGYSDPSDVPDKHYPKDILIPPEGELDADLRKTLILRAGVTMRL 13341

Query: 1931  TITGFQVDAVPANGQTPIQRT-IKPDVRSYTITGLQ-PGTDYKIYLYTLNDN-------- 1980
                      VP  G+ P + T  KP+V      GL    TD+  +L   N N        
Sbjct: 13342 --------YVPVKGRPPPKITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKYI 13393

Query: 1981  --------ARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPP----RARITGYIIKY 2028
                      +   +V+        P N+     + +S  V+W+PP     + I  Y+++ 
Sbjct: 13394 LTLENSCGKKEYTIVVKVLDTPGPPVNVTVKEISKDSAYVTWEPPIIDGGSPIINYVVQK 13453

Query: 2029  EKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIA 2066
                       V       T   +  LE G  Y   V A
Sbjct: 13454 RDAERKSWSTV-TTECSKTSFRVANLEEGKSYFFRVFA 13490



 Score =  102 bits (255), Expect = 3e-21
 Identities = 297/1362 (21%), Positives = 483/1362 (35%), Gaps = 240/1362 (17%)

Query: 908   PSP-RDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTG 966
             P P R+L+ V+V+  + T+ W PPE    G  +     N   E  +   +  +T++  T 
Sbjct: 11925 PGPVRNLKIVDVSSDRCTVCWDPPEDD-GGCEIQ----NYILEKCETKRMVWSTYS-ATV 11978

Query: 967   LSPGVT---------YYFKVFAVSH-----GRESKPLTAQQTTKLDAP-----TNLQFVN 1007
             L+PG T         Y F+V A +        ESKP+ A+  TK D P       +  V+
Sbjct: 11979 LTPGTTVTRLIEGNEYIFRVRAENKIGTGPPTESKPVIAK--TKYDKPGRPDPPEVTKVS 12036

Query: 1008  ETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSV---SKYPLRNLQPAS 1060
             + + TV+  W PP       ITGY L      +   R   V  S     +  ++NL P  
Sbjct: 12037 KEEMTVV--WNPPEYDGGKSITGYFLEK--KEKHSTRWVPVNKSAIPERRMKVQNLLPDH 12092

Query: 1061  EYTVSLVAIK----GNQESPKATGVFTT-LQPGSSIPPYNTEVTETT---IVITWTP--- 1109
             EY   + A      G    P    V    ++P    PP N  V +TT   I + W     
Sbjct: 12093 EYQFRVKAENEIGIGEPSLPSRPVVAKDPIEPPG--PPTNFRVVDTTKHSITLGWGKPVY 12150

Query: 1110  ---APRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPI 1166
                AP IG+ + +RP     +P     D G    +     V   +T+  L + QE +  +
Sbjct: 12151 DGGAPIIGYVVEMRPKIADASP-----DEGWKRCNAAAQLVRKEFTVTSLDENQEYEFRV 12205

Query: 1167  VNKVVTPLSPPTNLHLEANP-----------DTGVLTVSWERSTTPD--ITGYRITTTPT 1213
               +    +  P  L     P           D  +  +   R+  P       R    P 
Sbjct: 12206 CAQNQVGIGRPAELKEAIKPKEILEPPEIDLDASMRKLVIVRAGCPIRLFAIVRGRPAPK 12265

Query: 1214  NGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDD-------------KESVPIS 1260
                +   ++ VV   Q      +L   + + V   + +DD             +++V ++
Sbjct: 12266 VTWRKVGIDNVVRKGQV-----DLVDTMAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFVN 12320

Query: 1261  DTIIPEVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGYRIT--VVAAGEGIPIFEDFVDS 1318
               ++     ++DL   D+T +S  + W P  +    G ++T  +V   E        V  
Sbjct: 12321 VRVLDTPGPVSDLKVSDVTKTSCHVSWAPPENDG--GSQVTHYIVEKREADRKTWSTVTP 12378

Query: 1319  SVGY--YTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAVP-------PPTDLRFTNI 1369
              V    + VT L PG +Y   V  +   G   PT + +            PP  L  T +
Sbjct: 12379 EVKKTSFHVTNLVPGNEYYFRVTAVNEYGPGVPTDVPKPVLASDPLSEPDPPRKLEVTEM 12438

Query: 1370  GPDTMRVTWAPP---PSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYV 1426
               ++  + W PP       +  ++  Y   +   D         D ++V+T L  G +Y 
Sbjct: 12439 TKNSATLAWLPPLRDGGAKIDGYITSYREEEQPADRWTEYSVVKDLSLVVTGLKEGKKYK 12498

Query: 1427  VSVSSVYEQHESTPLRGR----QKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIR 1482
               V++      S P         K  L  P  +    IT  +             G ++R
Sbjct: 12499 FRVAARNAVGVSLPREAEGVYEAKEQLLPPKILMPEQITIKA-------------GKKLR 12545

Query: 1483  HHPEHFSGRPR--------EDRV----------PHSRNSITLTNLTPGTEYVVSIVALNG 1524
                 H  G+P         ED V            S + + + ++T       S+ A N 
Sbjct: 12546 IEA-HVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGYYSLTAENS 12604

Query: 1525  R----EESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAP----AVTVRYYRITYGET 1576
                  ++  +++         P D+  + A   SL  SW  P       +  Y +   + 
Sbjct: 12605 SGTDTQKIKVVVMDAPGPPQPPFDISDIDADACSL--SWHIPLEDGGSNITNYIVEKCDV 12662

Query: 1577  GGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDS-PASSKPISINYRTEI-D 1634
                  V       +K++  +  L PG +Y   V A    G S P +S  +   +   +  
Sbjct: 12663 SRGDWVTALASV-TKTSCRVGKLIPGQEYIFRVRAENRFGISEPLTSPKMVAQFPFGVPS 12721

Query: 1635  KPSQMQVTDVQDNSISVKW-LPSS---SPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTI 1690
             +P   +VT V  + I V W  P S   SP+ GY +    +N     K        TE   
Sbjct: 12722 EPKNARVTKVNKDCIFVAWDRPDSDGGSPIIGYLIERKERNSLLWVKANDTLVRSTEYPC 12781

Query: 1691  EGLQPTVEYVVSVYAQNPSGESQPLVQTAVTN----IDRPKGLAFTDVDVDSIKIAWESP 1746
              GL   +EY   +YA N +G S P   T        +D P      DV   ++ + W  P
Sbjct: 12782 AGLVEGLEYSFRIYALNKAGSSPPSKPTEYVTARMPVDPPGKPEVIDVTKSTVSLIWARP 12841

Query: 1747  QGQVSRYRVTY-----SSPEDGIHELFPAPDG---EEDTAELQGLRPGSEYTVSVVALHD 1798
             +       + Y       P D       AP     EE TA   GL   ++Y    +A   
Sbjct: 12842 KHDGGSKIIGYFVEACKLPGDKWVRCNTAPHQIPQEEYTAT--GLEEKAQYQFRAIARTA 12899

Query: 1799  DMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLT-GYRVRVTPKEKTG--- 1854
                S P           P+D       P ++ A+  PP + L+   +  +T K  T    
Sbjct: 12900 VNISPP---------SEPSD-------PVTILAENVPPRIDLSVAMKSLLTVKAGTNVCL 12943

Query: 1855  -------PMKEINLAPDSSSVV-VSGLMVATKYEVSVYAL-----KD----TLTSRPAQG 1897
                    PM  ++   D + +    G+ +A +  +    L     KD    T+T+  + G
Sbjct: 12944 DATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTITAENSSG 13003

Query: 1898  V------VTTLENVSPPRRARVTDATETTITISWRTKTET----ITGFQVDAVPANGQTP 1947
                    +  L+   PP   ++         +SW    E     IT + VD    +    
Sbjct: 13004 SKSATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYIVDKRETSRPNW 13063

Query: 1948  IQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTA---IDAPSNLR--- 2001
              Q +    + S ++  L  G +Y+  +   N      PV  + + A    D P       
Sbjct: 13064 AQVSATVPITSCSVEKLIEGHEYQFRICAENKYGVGDPVFTEPAIAKNPYDPPGRCDPPV 13123

Query: 2002  FLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREVVPRPRPGVTEATI--TGLE 2055
                 T + + VSW+PP     + ITGY++  EK  +         R  + E T+  TGL+
Sbjct: 13124 ISNITKDHMTVSWKPPADDGGSPITGYLL--EKRETQAVNWTKVNRKPIIERTLKATGLQ 13181

Query: 2056  PGTEYTIYVIALKNNQKSEPLIGRKKTVQKTPFVTHPGYDTG 2097
              GTEY   V A+    K+ P  G+     K  +   P Y  G
Sbjct: 13182 EGTEYEFRVTAI---NKAGP--GKPSDASKAAYARDPQYPPG 13218



 Score =  102 bits (255), Expect = 3e-21
 Identities = 274/1373 (19%), Positives = 474/1373 (34%), Gaps = 187/1373 (13%)

Query: 766   LDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDT 825
             +DL  T   + IP+         ++  ++  GE+++ ++      P    D  V  V  T
Sbjct: 12282 VDLVDTMAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFVNVRVLDTPGPVSDLKVSDVTKT 12341

Query: 826   SIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETAN-SVTLSDLQPGVQYNITI 880
             S  V W+ P+    + +T Y IV     +  +     PE    S  +++L PG +Y   +
Sbjct: 12342 SCHVSWAPPENDGGSQVTHY-IVEKREADRKTWSTVTPEVKKTSFHVTNLVPGNEYYFRV 12400

Query: 881   YAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTG 936
              AV E     P  + +    +        PR L+  E+T    T+ W PP     + + G
Sbjct: 12401 TAVNEYGPGVPTDVPKPVLASDPLSEPDPPRKLEVTEMTKNSATLAWLPPLRDGGAKIDG 12460

Query: 937   YRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTK 996
             Y         P +      + ++    VTGL  G  Y F+V             A+    
Sbjct: 12461 YITSYREEEQPADRWTEYSVVKDLSLVVTGLKEGKKYKFRV------------AARNAVG 12508

Query: 997   LDAPTNLQFVNETDSTVLVRWTPPR----AQIT---GYRLTVGLTRRGQPR--------- 1040
             +  P   + V E    +L    PP+     QIT   G +L +     G+P          
Sbjct: 12509 VSLPREAEGVYEAKEQLL----PPKILMPEQITIKAGKKLRIEAHVYGKPHPTCKWKKGE 12564

Query: 1041  ---------QYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSI 1091
                        +   S S   ++++        SL A   +    +   V     PG   
Sbjct: 12565 DEVVTSSHLAVHKADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPGPPQ 12624

Query: 1092  PPYN-TEVTETTIVITW-TPAPRIGFKL------GVRPSQGGEAPREVTSDSGSIVVSGL 1143
             PP++ +++      ++W  P    G  +          S+G       +    S  V  L
Sbjct: 12625 PPFDISDIDADACSLSWHIPLEDGGSNITNYIVEKCDVSRGDWVTALASVTKTSCRVGKL 12684

Query: 1144  TPGVEYVYTIQVLRDGQERDAPIVNKVV------TPLSPPTNLHLEANPDTGVLTVSWER 1197
              PG EY++ ++        +     K+V       P  P      + N D   + V+W+R
Sbjct: 12685 IPGQEYIFRVRAENRFGISEPLTSPKMVAQFPFGVPSEPKNARVTKVNKD--CIFVAWDR 12742

Query: 1198  STT---PDITGYRITTTPTNGQQG-NSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDD 1253
               +     I GY I     N      + + +V + +  C    L  GLEY+  +Y +   
Sbjct: 12743 PDSDGGSPIIGYLIERKERNSLLWVKANDTLVRSTEYPCA--GLVEGLEYSFRIYALNKA 12800

Query: 1254  KESVPISDTIIPEVPQLTD----LSFVDITDSSIGLRWTPL---NSSTIIGYRITVV--- 1303
               S P   T         D       +D+T S++ L W        S IIGY +      
Sbjct: 12801 GSSPPSKPTEYVTARMPVDPPGKPEVIDVTKSTVSLIWARPKHDGGSKIIGYFVEACKLP 12860

Query: 1304  --------AAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVI--TLIN----GGESAP 1349
                      A   IP  E         YT TGLE    Y    I  T +N       S P
Sbjct: 12861 GDKWVRCNTAPHQIPQEE---------YTATGLEEKAQYQFRAIARTAVNISPPSEPSDP 12911

Query: 1350  TTLTQQTAVPPPTDLRF-----------TNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKN 1398
              T+  +  VPP  DL             TN+  D   V   P P++          P + 
Sbjct: 12912 VTILAEN-VPPRIDLSVAMKSLLTVKAGTNVCLDA-TVFGKPMPTVSWKKDGTLLKPAEG 12969

Query: 1399  EEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHEST-PLRGRQKTGLDSPTGIDF 1457
              +   + ++   +  +   N     +Y ++  +      +T  L+   K G   P  +  
Sbjct: 12970 IKMAMQRNLCTLE--LFSVNRKDSGDYTITAENSSGSKSATIKLKVLDKPG--PPASVKI 13025

Query: 1458  SDITANSFTVHWIAP----RATITGYRIRHHPEHFSGRPREDRVPHS--RNSITLTNLTP 1511
             + + ++   + W  P     + IT Y +    +  + RP   +V  +    S ++  L  
Sbjct: 13026 NKMYSDRAMLSWEPPLEDGGSEITNYIV---DKRETSRPNWAQVSATVPITSCSVEKLIE 13082

Query: 1512  GTEYVVSIVALNGREESPLLIGQQSTVS---DVPR--DLEVVA-ATPTSLLISWDAPA-- 1563
             G EY   I A N       +  + +      D P   D  V++  T   + +SW  PA  
Sbjct: 13083 GHEYQFRICAENKYGVGDPVFTEPAIAKNPYDPPGRCDPPVISNITKDHMTVSWKPPADD 13142

Query: 1564  --VTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRG---DS 1618
                 +  Y +   ET   +  +    P  + T   +GL+ G +Y   V A+   G    S
Sbjct: 13143 GGSPITGYLLEKRETQAVNWTKVNRKPIIERTLKATGLQEGTEYEFRVTAINKAGPGKPS 13202

Query: 1619  PASSKPISINYRTEIDKPSQMQVTDVQDNSISVKW----LPSSSPVTGYRVTTTPKNGPG 1674
              AS    + + +     P+  +V D   +S+S+ W        SP+ GY V     +   
Sbjct: 13203 DASKAAYARDPQYPPGPPAFPKVYDTTRSSVSLSWGKPAYDGGSPIIGYLVEVKRADSDN 13262

Query: 1675  PTKTK-TAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFT- 1732
               +        +T   + GL    +Y   VYA N  G S P   + V +   PK +    
Sbjct: 13263 WVRCNLPQNLQKTRFEVTGLMEDTQYQFRVYAVNKIGYSDP---SDVPDKHYPKDILIPP 13319

Query: 1733  --DVDVDSIKIAWESPQGQVSRY---------RVTYSSPEDGIHELFPAPDGEED----- 1776
               ++D D  K         +  Y         ++T+S P   + +         D     
Sbjct: 13320 EGELDADLRKTLILRAGVTMRLYVPVKGRPPPKITWSKPNVNLRDRIGLDIKSTDFDTFL 13379

Query: 1777  TAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPP 1836
               E        +Y +++       E   ++    T  P P ++   +++  S    W PP
Sbjct: 13380 RCENVNKYDAGKYILTLENSCGKKEYTIVVKVLDTPGP-PVNVTVKEISKDSAYVTWEPP 13438

Query: 1837  NVQ----LTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTS 1892
              +     +  Y V+    E+      +      +S  V+ L     Y   V+A  +    
Sbjct: 13439 IIDGGSPIINYVVQKRDAERKS-WSTVTTECSKTSFRVANLEEGKSYFFRVFAENEYGIG 13497

Query: 1893  RPAQ--GVVTTLENVSPPRRARVTDATETTITISWRTK----TETITGFQVDAVPANGQT 1946
              P +    V   +   P    +V   ++++ +I W+         I G+ VD +    + 
Sbjct: 13498 DPGETRDAVKASQTPGPVVDLKVRSVSKSSCSIGWKKPHSDGGSRIIGYVVDFLTEENKW 13557

Query: 1947  PIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSP--VVIDASTAIDAP 1997
               QR +K     Y+   L  G +Y   +   N+N   +P  + + A   + AP
Sbjct: 13558 --QRVMKSLSLQYSAKDLTEGKEYTFRVSAENENGEGTPSEITVVARDDVVAP 13608



 Score =  102 bits (255), Expect = 3e-21
 Identities = 328/1625 (20%), Positives = 588/1625 (36%), Gaps = 231/1625 (14%)

Query: 609   SGPVEVFITETPSQ----------PNSHPIQWNAPQ---PSHISKYILRWRPKNSVGRWK 655
             SG V V + +TP             +S  + W+ P     S I+ YI+  R       + 
Sbjct: 14485 SGFVNVRVLDTPGPVLNLRPTDITKDSVTLHWDLPLIDGGSRITNYIVEKREATRKS-YS 14543

Query: 656   EATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGET 715
              AT   H  +Y + GL  G  Y  ++++  +YG  E        T T+ PV ++      
Sbjct: 14544 TATTKCHKCTYKVTGLSEGCEYFFRVMAENEYGIGE-------PTETTEPVKASE----- 14591

Query: 716   TPFSPLVATSESVTEITASSFVVSWVS----ASDTVSGFRVEYELSEEGDEPQYLDLPST 771
                +P    S ++ +IT S+  ++W          ++G+ +E +  +  D+  ++     
Sbjct: 14592 ---APSPPDSLNIMDITKSTVSLAWPKPKHDGGSKITGYVIEAQ-RKGSDQWTHITTVKG 14647

Query: 772   ATSVNIPDLLPGRKYIVNVYQISEDG-----EQSLILSTSQTTAPDAPPDPTVDQV---- 822
                V + +L  G +Y   V  ++  G     E   ++   QT  P+        ++    
Sbjct: 14648 LECV-VRNLTEGEEYTFQVMAVNSAGRSAPRESRPVIVKEQTMLPELDLRGIYQKLVIAK 14706

Query: 823   --DDTSIVVR-WSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNIT 879
               D+  + +    RP+  +T  +      +   +  +N   TA S T+ ++   V+ +  
Sbjct: 14707 AGDNIKVEIPVLGRPKPTVTWKK---GDQILKQTQRVNFETTATS-TILNINECVRSDSG 14762

Query: 880   IYAVEENQESTPV--VIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPES----A 933
              Y +        V  VI  +    P   T P    ++F EV+   VT  W PPE+     
Sbjct: 14763 PYPLTARNIVGEVGDVITIQVHDIPGPPTGP----IKFDEVSSDFVTFSWDPPENDGGVP 14818

Query: 934   VTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKV-----FAVSHGRESKP 988
             ++ Y V++   +          + R T+ + T L+ G+ Y F+V     + V  G  S  
Sbjct: 14819 ISNYVVEMRQTDSTTWVELATTVIRTTY-KATRLTTGLEYQFRVKAQNRYGVGPGITSAC 14877

Query: 989   LTAQQTTKLDAPTNL-QFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPS 1047
             + A    K+  P    Q    T  ++ + W  P +   G    +G     + R   +  +
Sbjct: 14878 IVANYPFKVPGPPGTPQVTAVTKDSMTISWHEPLSD--GGSPILGYHVERKERNGILWQT 14935

Query: 1048  VSK-------YPLRNLQPASEYTVSLVA--IKGNQESPKATGVFTTLQP----GSSIPPY 1094
             VSK       +    L     Y   ++A  + G  +  K +     L P    G  +P  
Sbjct: 14936 VSKALVPGNIFKSSGLTDGIAYEFRVIAENMAGKSKPSKPSEPMLALDPIDPPGKPVP-- 14993

Query: 1095  NTEVTETTIVITWT-PAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTI 1153
                +T  T+ + W  P    GFK+     +  + P      +G  + +  +  +E  +T+
Sbjct: 14994 -LNITRHTVTLKWAKPEYTGGFKITSYIVEKRDLP------NGRWLKANFSNILENEFTV 15046

Query: 1154  QVLRDGQERDAPIVNK----VVTPLSPPTNL-----HLEANP--------DTGVLTVSWE 1196
               L +    +  ++ K     ++P S P++       +EA          DT +L     
Sbjct: 15047 SGLTEDAAYEFRVIAKNAAGAISPPSEPSDAITCRDDVEAPKIKVDVKFKDTVILKAGEA 15106

Query: 1197  RSTTPDITGYRITTTPTNGQQGNSLE-------------------EVVHADQSSCTFDNL 1237
                  D++G R   T    + G  LE                   +    D  + T    
Sbjct: 15107 FRLEADVSG-RPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDSGAYTLTAT 15165

Query: 1238  SPGLEYNVSVYTVKDDKESVPISDTIIPEVPQLTDLSFVDITDSSIGLRWTPL--NSSTI 1295
             +PG  +   ++ VK      P      PE P    L+  ++T     L W P   +    
Sbjct: 15166 NPG-GFAKHIFNVKVLDRPGP------PEGP----LAVTEVTSEKCVLSWFPPLDDGGAK 15214

Query: 1296  IGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGG-----ESAPT 1350
             I + I        +       +  V    VT L  G +Y   V+ +   G     ES P 
Sbjct: 15215 IDHYIVQKRETSRLAWTNVASEVQVTKLKVTKLLKGNEYIFRVMAVNKYGVGEPLESEPV 15274

Query: 1351  TLTQQTAVP-PPTDLRFTNIGPDTMRVTWAPPPS---IDLTNFLVRYSPVKNEEDVAELS 1406
                     P PP +   T I  D+M V W  P S    ++ N++V       +  +    
Sbjct: 15275 LAVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEIINYIVERRDKAGQRWIKCNK 15334

Query: 1407  ISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTP------LRGRQKTGLDSPTGID-FSD 1459
              + +D    ++ L  G EY   + +      S P       +         P G     D
Sbjct: 15335 KTLTDLRYKVSGLTEGHEYEFRIMAENAAGISAPSPTSPFYKACDTVFKPGPPGNPRVLD 15394

Query: 1460  ITANSFTVHWIAP----RATITGYRIRHH-PEHFSGRPREDRVPHSRNSITLTNLTPGTE 1514
              + +S ++ W  P     + ITGY +    PE    +           S T+T LT   E
Sbjct: 15395 TSRSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQIVTPPAGLKATSYTITGLTENQE 15454

Query: 1515  YVVSIVALNG-------------REESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDA 1561
             Y + I A+N              + E  +L  +    +D+ + + + A     L +    
Sbjct: 15455 YKIRIYAMNSEGLGEPALVPGTPKAEDRMLPPEIELDADLRKVVTIRACCTLRLFVPIKG 15514

Query: 1562  -PAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPA 1620
              PA  V++ R  +GE+   + ++      S S+ T+  +     +    Y +T    S +
Sbjct: 15515 RPAPEVKWAR-DHGESLDKASIE------STSSYTLLIVGNVNRFDSGKYILTVENSSGS 15567

Query: 1621  SSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLP----SSSPVTGYRVTTTPKNGPGPT 1676
              S  +++        P  ++V +V   S+++ W P      S +  Y V          +
Sbjct: 15568 KSAFVNVRVLDTPGPPQDLKVKEVTKTSVTLTWDPPLLDGGSKIKNYIVEKRESTRKAYS 15627

Query: 1677  KTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPL-VQTAVTNIDRPKG---LAFT 1732
                T    +T   ++ LQ    Y   V A+N  G   P     +V   +RP     +   
Sbjct: 15628 TVAT-NCHKTSWKVDQLQEGCSYYFRVLAENEYGIGLPAETAESVKASERPLPPGKITLM 15686

Query: 1733  DVDVDSIKIAWESPQGQVSRYRVTY--SSPEDGIHELFPAPDGEEDTAELQGLRPGSEYT 1790
             DV  +S+ ++WE P+       + Y       G  +       +   A + GL  G EY+
Sbjct: 15687 DVTRNSVSLSWEKPEHDGGSRILGYIVEMQTKGSDKWATCATVKVTEATITGLIQGEEYS 15746

Query: 1791  VSVVALHDDMESQPL-----IGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRV 1845
               V A ++   S P      +  +   IP    L F   T T L+ +    +V   G   
Sbjct: 15747 FRVSAQNEKGISDPRQLSVPVIAKDLVIPPAFKLLFN--TFTVLAGEDLKVDVPFIGRPT 15804

Query: 1846  -RVTPKEKTGPMKEINLAPDSSSVVVSGLMV--ATKYEVSVYALKDTLTSRPAQGV---- 1898
               VT  +   P+K+       S+   S L +  A + +V  Y +K  LT+   + +    
Sbjct: 15805 PAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVK--LTNSAGEAIETLN 15862

Query: 1899  VTTLENVSPPR-RARVTDATETTITISWRTKT----ETITGFQVDAVPANGQTPIQRTIK 1953
             V  L+   PP    ++ + T  +IT+SW         +I  + V+    +  T   + + 
Sbjct: 15863 VIVLDKPGPPTGPVKMDEVTADSITLSWGPPKYDGGSSINNYIVE--KRDTSTTTWQIVS 15920

Query: 1954  PDVRSYTITG--LQPGTDYKIYL-----YTLNDNARSSPVVIDASTAIDAPSNLRFLA-T 2005
               V   TI    L+ G +Y+  +     Y  +    S P V      +  P     +  +
Sbjct: 15921 ATVARTTIKACRLKTGCEYQFRIAAENRYGKSTYLNSEPTVAQYPFKVPGPPGTPVVTLS 15980

Query: 2006  TPNSLLVSWQPP----RARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYT 2061
             + +S+ V W  P     +R+ GY ++ ++  S     + +     T+   TGLE G EY 
Sbjct: 15981 SRDSMEVQWNEPISDGGSRVIGYHLERKERNSILWVKLNKTPIPQTKFKTTGLEEGVEYE 16040

Query: 2062  IYVIA 2066
               V A
Sbjct: 16041 FRVSA 16045



 Score =  102 bits (255), Expect = 3e-21
 Identities = 306/1554 (19%), Positives = 528/1554 (33%), Gaps = 201/1554 (12%)

Query: 610   GPVEVFITETPSQPNSHPIQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSY 666
             GP E  +  T        + WN P     ++IS YI+  R  + +  W + +      +Y
Sbjct: 18431 GPPEGPLKVTGVTAEKCYLAWNPPLQDGGANISHYIIEKRETSRLS-WTQVSTEVQALNY 18489

Query: 667   TIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSE 726
              +  L PG  Y  +++++ +YG  E             P+ S  VT       P   ++ 
Sbjct: 18490 KVTKLLPGNEYIFRVMAVNKYGIGE-------------PLESGPVTACNPYKPPGPPSTP 18536

Query: 727   SVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDE-----PQYLDLPSTATSVNIPDLL 781
              V+ IT  S VV+W    D   G  +E  + E+ D+      +      T   + +  L 
Sbjct: 18537 EVSAITKDSMVVTWARPVDD-GGTEIEGYILEKRDKEGVRWTKCNKKTLTDLRLRVTGLT 18595

Query: 782   PGRKY-----IVNVYQISEDGEQSLILSTSQTTAPDAPP-DPTVDQVDDTSIVVRWSRP- 834
              G  Y       N   + E  E S+         P  PP +P V     +S+ + WS+P 
Sbjct: 18596 EGHSYEFRVAAENAAGVGEPSEPSVFYRACDALYPPGPPSNPKVTDTSRSSVSLAWSKPI 18655

Query: 835   ---QAPITGYRIVYSPSVEGSSTELNLPE--TANSVTLSDLQPGVQYNITIYAVEENQES 889
                 AP+ GY +    +     T    P        T++ L+   +YN  I A+      
Sbjct: 18656 YDGGAPVKGYVVEVKEAAADEWTTCTPPTGLQGKQFTVTKLKENTEYNFRICAINSEGVG 18715

Query: 890   TPVVIQQETTGTPRSD--TVPSPRDLQFVEVTDVKVTI-----MWTPPESAVTGYRVDVI 942
              P  +        R +   +    DL+ V V     T+     +   PE  V   + + I
Sbjct: 18716 EPATLPGSVVAQERIEPPEIELDADLRKVVVLRASATLRLFVTIKGRPEPEVKWEKAEGI 18775

Query: 943   PVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTN 1002
               +   +       +      VT    G   Y      + G ++  +  +      AP N
Sbjct: 18776 LTD-RAQIEVTSSFTMLVIDNVTRFDSG--RYNLTLENNSGSKTAFVNVRVLDSPSAPVN 18832

Query: 1003  LQFVNETDSTVLVRWTPP----RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQP 1058
             L        +V + W PP     A+IT Y +    T R          + + + + NLQ 
Sbjct: 18833 LTIREVKKDSVTLSWEPPLIDGGAKITNYIVEKRETTRKAYATITNNCTKTTFRIENLQE 18892

Query: 1059  ASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYN------TEVTETTIVITW-TPAP 1111
                Y   ++A   + E        TT     S PP         +VT  T  I W  P  
Sbjct: 18893 GCSYYFRVLA---SNEYGIGLPAETTEPVKVSEPPLPPGRVTLVDVTRNTATIKWEKPES 18949

Query: 1112  RIGFKLG----VRPSQGGEAPREVTS-DSGSIVVSGLTPGVEYVYTIQVLR-----DGQE 1161
               G K+        ++G E     T   +    +SGLT G EYV+ +  +      D ++
Sbjct: 18950 DGGSKITGYVVEMQTKGSEKWSTCTQVKTLEATISGLTAGEEYVFRVAAVNEKGRSDPRQ 19009

Query: 1162  RDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDIT-GYRITTTPTNGQQGNS 1220
                P++ + +  + P   L            V        D+    R   T    + G +
Sbjct: 19010 LGVPVIARDI-EIKPSVELPFH------TFNVKAREQLKIDVPFKGRPQATVNWRKDGQT 19062

Query: 1221  LEEVVHADQSS---CTFDNLSPGLEYNVSVY--TVKDDKESVPISDTII------PEVPQ 1269
             L+E    + SS    T  ++    + +V  Y   V +   S+ +  TII      P  P 
Sbjct: 19063 LKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSNSAGSITVPITIIVLDRPGPPGPI 19122

Query: 1270  LTDLSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIFEDFVDSSVGYYT--VTG 1327
               D    +++  SI + W P            +V   E        V  +V   +  +  
Sbjct: 19123 RID----EVSCDSITISWNPPEYDGGCQISNYIVEKKETTSTTWHIVSQAVARTSIKIVR 19178

Query: 1328  LEPGIDYDISVITLINGGESAPTTLTQQTA------VPPPTDLRFTNIGPDTMRVTWAPP 1381
             L  G +Y   V      G+S+ +  +   A        PP   +  +    TM VTW  P
Sbjct: 19179 LTTGSEYQFRVCAENRYGKSSYSESSAVVAEYPFSPPGPPGTPKVVHATKSTMLVTWQVP 19238

Query: 1382  PSIDLTNFLVRYSPVKNEEDV---AELSISPSDNAVVLTNLLPGTEY--------VVSVS 1430
              +   +  +  +   K    +       I  +D  + ++ L  G  Y        +  + 
Sbjct: 19239 VNDGGSRVIGYHLEYKERSSILWSKANKILIADTQMKVSGLDEGLMYEYRVYAENIAGIG 19298

Query: 1431  SVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPR----ATITGYRIRHHPE 1486
                +  E  P R       D P   + ++IT  S ++ W  P     A ITGY +    E
Sbjct: 19299 KCSKSCEPVPAR----DPCDPPGQPEVTNITRKSVSLKWSKPHYDGGAKITGYIVERR-E 19353

Query: 1487  HFSGRPREDRVPHSRNS-ITLTNLTPGTEYVVSIVALNGREE--------SPLLIGQQST 1537
                GR  +    + + +   +T LT    Y   + A N  +          P+++     
Sbjct: 19354 LPDGRWLKCNYTNIQETYFEVTELTEDQRYEFRVFARNAADSVSEPSESTGPIIVKDDVE 19413

Query: 1538  VSDVPRDLE----VVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKST 1593
                V  D++    +V      L I+ D     +    I++ + G     +  T   S   
Sbjct: 19414 PPRVMMDVKFRDVIVVKAGEVLKINADIAGRPLPV--ISWAKDGIEIEERARTEIISTDN 19471

Query: 1594  ATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKP----SQMQVTDVQDNSI 1649
              T+  +K  +      Y +T +  + A ++ +++N +  +DKP      +++  +     
Sbjct: 19472 HTLLTVKDCIRRDTGQYVLTLK--NVAGTRSVAVNCKV-LDKPGPPAGPLEINGLTAEKC 19528

Query: 1650  SVKW---LPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQ 1706
             S+ W            Y +    +               T   +  L    EY+  V   
Sbjct: 19529 SLSWGRPQEDGGADIDYYIVEKRETSHLAWTICEGELQMTSCKVTKLLKGNEYIFRVTGV 19588

Query: 1707  NPSGESQPLVQTAVTNID------RPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSP 1760
             N  G  +PL   A+  +D       P  L  T V  +S+ + W  P+         Y   
Sbjct: 19589 NKYGVGEPLESVAIKALDPFTVPSPPTSLEITSVTKESMTLCWSRPESDGGSEISGYIIE 19648

Query: 1761  EDGIHELFPAPDGEEDTAELQ----GLRPGSEYTVSVVA-----LHDDMESQPLIGTQST 1811
                 + L      ++   +L+    GLR G EY   V A     L    E+ PLI  +  
Sbjct: 19649 RREKNSLRWVRVNKKPVYDLRVKSTGLREGCEYEYRVYAENAAGLSLPSETSPLIRAEDP 19708

Query: 1812  A-IPA-PTDLKFTQVTPTSLSAQWTPP----NVQLTGYRVRVTPKEKTGPMKEINLAPDS 1865
               +P+ P+  K      T+++  W  P       +TGY V     + T     I  +   
Sbjct: 19709 VFLPSPPSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEYKKSDDTDWKTSIQ-SLRG 19767

Query: 1866  SSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENV----------SPPRRARVTD 1915
             +   +SGL    +Y   V ++     S P+      +             S  R+  +  
Sbjct: 19768 TEYTISGLTTGAEYVFRVKSVNKVGASDPSDSSDPQIAKEREEEPLFDIDSEMRKTLIVK 19827

Query: 1916  A-TETTITISWRTK-----------TETITGFQVDAVPANGQTPIQRTIKPDVRSYTITG 1963
             A    T+T+ +R +           T+  T   VD   +     I+   + D   YT+T 
Sbjct: 19828 AGASFTMTVPFRGRPVPNVLWSKPDTDLRTRAYVDTTDSRTSLTIENANRNDSGKYTLT- 19886

Query: 1964  LQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPP 2017
             +Q              +A S  +V+        P+N+     T  S ++SW  P
Sbjct: 19887 IQNVL-----------SAASLTLVVKVLDTPGPPTNITVQDVTKESAVLSWDVP 19929



 Score =  100 bits (248), Expect = 2e-20
 Identities = 162/726 (22%), Positives = 275/726 (37%), Gaps = 92/726 (12%)

Query: 1268  PQLTDLSFVDITDSSIGLRWTPLN---SSTIIGYRITVVAAGEG--IPIFEDFVDSSVGY 1322
             P    +   +I  +SI + W P      + + GY +    A     +P+ E    S+   
Sbjct: 23462 PPTGPIKIDEIDATSITISWEPPELDGGAPLSGYVVEQRDAHRPGWLPVSESVTRST--- 23518

Query: 1323  YTVTGLEPGIDYDISVITLINGG-----ESAPTTLTQQTAVP-PPTDLRFTNIGPDTMRV 1376
             +  T L  G +Y   V      G     +S          +P PP  L+  ++  D M +
Sbjct: 23519 FKFTRLTEGNEYVFRVAATNRFGIGSYLQSEVIECRSSIRIPGPPETLQIFDVSRDGMTL 23578

Query: 1377  TWAPPPS---IDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVY 1433
             TW PP       +T ++V    V+ +  V    +  +      T L  G EY   V+++ 
Sbjct: 23579 TWYPPEDDGGSQVTGYIVERKEVRADRWVRVNKVPVTMTRYRSTGLTEGLEYEHRVTAIN 23638

Query: 1434  EQHESTPLR-GRQKTGLD------SPTGIDFSDITANSFTVHWIAPR----ATITGYRIR 1482
              +    P R  +    +D       P     +D T  S ++ W  P     + +TGY I 
Sbjct: 23639 ARGSGKPSRPSKPIVAMDPIAPPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIE 23698

Query: 1483  HHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVP 1542
                       + +  P      TLT+L  G EY   ++A N         G     ++VP
Sbjct: 23699 MQKVDQHEWTKCNTTPTKIREYTLTHLPQGAEYRFRVLACNA--------GGPGEPAEVP 23750

Query: 1543  RDLEVVAAT--PTSLLISWDAPAVTVRY---YRITYGETGGNSPVQEFTVPGSKSTATIS 1597
               ++V      P   L       + VR     R+T    G   P+ ++T  G +  +  +
Sbjct: 23751 GTVKVTEMLEYPDYELDERYQEGIFVRQGGVIRLTIPIKGKPFPICKWTKEG-QDISKRA 23809

Query: 1598  GLKPGVDYTITVYAVTGRGDS---------PASSKPISINYRTEIDKPSQ----MQVTDV 1644
              +     +T  V     RGDS             K + I  R  I  P+     ++  D+
Sbjct: 23810 MIATSETHTELVIKEADRGDSGTYDLVLENKCGKKAVYIKVRV-IGSPNSPEGPLEYDDI 23868

Query: 1645  QDNSISVKWLPSS----SPVTGYRVTT--TPKNGPGPTKTKTAGPDQTEMTIEGLQPTVE 1698
             Q  S+ V W P +    + + GY +     PK       ++  G   T + ++GL+  VE
Sbjct: 23869 QVRSVRVSWRPPADDGGADILGYILERREVPKAAWYTIDSRVRG---TSLVVKGLKENVE 23925

Query: 1699  YVVSVYAQNPSGESQPLVQ----TAVTNIDRPKGLA----FTDVDVDSIKIAWESPQGQ- 1749
             Y   V A+N  G S+PL      T  T ++ P+  +      DV   S+ ++W  P+   
Sbjct: 23926 YHFRVSAENQFGISKPLKSEEPVTPKTPLNPPEPPSNPPEVLDVTKSSVSLSWSRPKDDG 23985

Query: 1750  VSRYRVTYSSPEDGIHELFPAPDGEEDTAEL---QGLRPGSEYTVSVVALHD------DM 1800
              SR    Y   ++   + +   +  + T  +    GL P +EY   ++A +D        
Sbjct: 23986 GSRVTGYYIERKETSTDKWVRHNKTQITTTMYTVTGLVPDAEYQFRIIAQNDVGLSETSP 24045

Query: 1801  ESQPLIGTQSTAIPA-PTDLKFTQVTPTSLSAQWTPPNV----QLTGYRVRVTPKEKTGP 1855
              S+P++       P+ P +L+   ++  S++ QW  P      ++ GY V       +  
Sbjct: 24046 ASEPVVCKDPFDKPSQPGELEILSISKDSVTLQWEKPECDGGKEILGYWVEYRQSGDSAW 24105

Query: 1856  MKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRP---AQGVVTTL-ENVSPPRRA 1911
              K            + GL+ AT+YE  V+A  +T  SRP   A  + T L    +P  R 
Sbjct: 24106 KKSNKERIKDKQFTIGGLLEATEYEFRVFAENETGLSRPRRTAMSIKTKLTSGEAPGIRK 24165

Query: 1912  RVTDAT 1917
              + D T
Sbjct: 24166 EMKDVT 24171



 Score = 99.8 bits (247), Expect = 3e-20
 Identities = 244/1107 (22%), Positives = 422/1107 (38%), Gaps = 171/1107 (15%)

Query: 1092 PPYNTEVTET---TIVITWT-PAPRIGFKLGVRPSQGGEAPREV------TSDSGSIVVS 1141
            P  N EVTET    + + W  P    G K+     +  +  R+        ++S    V+
Sbjct: 6720 PVRNLEVTETFDGEVSLAWEEPLTDGGSKIIGYVVERRDIKRKTWVLATDRAESCEFTVT 6779

Query: 1142 GLTPG-VEYVYTIQVLR-----DGQERDAPIV--NKVVTPLSPPTNLHLEANPDTGVLTV 1193
            GL  G VEY++ +         +  E D P+   +K   P  PP N+ +      GV ++
Sbjct: 6780 GLQKGGVEYLFRVSARNRVGTGEPVETDNPVEARSKYDVP-GPPLNVTITDVNRFGV-SL 6837

Query: 1194 SWERSTTP---DITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYT- 1249
            +WE        +IT Y I        + ++    V A+  S T  ++  G EY+  V   
Sbjct: 6838 TWEPPEYDGGAEITNYVIELRDKTSIRWDTAM-TVRAEDLSATVTDVVEGQEYSFRVRAQ 6896

Query: 1250 --VKDDKES-----VPISDTIIPEVPQLTDLSFVDITDSSIGLRWTPL---NSSTIIGYR 1299
              +   K S     V ++D I    P + +L+  D T SS+ L+W P      S I+GY 
Sbjct: 6897 NRIGVGKPSAATPFVKVADPIERPSPPV-NLTSSDQTQSSVQLKWEPPLKDGGSPILGYI 6955

Query: 1300 ITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLT------ 1353
            I     G+   I  +        Y VTGLE G  Y   V      G S P+ +       
Sbjct: 6956 IERCEEGKDNWIRCNMKLVPELTYKVTGLEKGNKYLYRVSAENKAGVSDPSEILGPLTAD 7015

Query: 1354 ----------------QQTAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVK 1397
                             +  VP P  +   + G      TW     +  T   V+   +K
Sbjct: 7016 DAFVEPTMDLSAFKDGLEVIVPNPITILVPSTGYPRPTATWCFGDKVLETGDRVK---MK 7072

Query: 1398 NEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHE-STPLRGRQKTGLDSPTGID 1456
                 AEL ISPS+ +      L     V ++S   + +  + P          +P  + 
Sbjct: 7073 TLSAYAELVISPSERSDKGIYTLKLENRVKTISGEIDVNVIARP---------SAPKELK 7123

Query: 1457 FSDITANSFTVHWIAP----RATITGYRIRHHPEHFSGRPREDRVPHSRNSI--TLTNLT 1510
            F DIT +S  + W  P     + +TGY +    +    R    +V      +  T+ +L 
Sbjct: 7124 FGDITKDSVHLTWEPPDDDGGSPLTGYVVE---KREVSRKTWTKVMDFVTDLEFTVPDLV 7180

Query: 1511 PGTEYVVSIVALN-------GREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAP- 1562
             G EY+  + A N          + P+ +   +TV D P +++    T  S+ ++WD P 
Sbjct: 7181 QGKEYLFKVCARNKCGPGEPAYVDEPVNMSTPATVPDPPENVKWRDRTANSIFLTWDPPK 7240

Query: 1563 ---AVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSP 1619
                  ++ Y +     G +  V     P +++   ++GL+ G  Y   V A+  +G   
Sbjct: 7241 NDGGSRIKGYIVERCPRGSDKWV-ACGEPVAETKMEVTGLEEGKWYAYRVKALNRQG--- 7296

Query: 1620 ASSKPISINYRTEIDKPS-QMQVTDVQDNS---ISVKWLPSSSPVTGYRV----TTTPKN 1671
             +SKP          +P+ ++Q  D Q+     + VK L   +   G ++    T T K 
Sbjct: 7297 -ASKP---------SRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKP 7346

Query: 1672 GPGPTKTKT--AGPDQTEMTIEGL--QPTVEYVVS---------VYAQNPSGESQPLVQT 1718
             P  T TK          +TIE +  + TV  V S         + A N  G +  +V+ 
Sbjct: 7347 EPKITWTKADMILKQDKRITIENVPKKSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEV 7406

Query: 1719 AVTNIDR---PKGLAFTDVDVDSIKIAWESPQ----GQVSRYRVTYSSPEDGI-HELFPA 1770
             V  +D+   P     TDV  +S  + W  P+     +++ Y V   + +  + H+L  +
Sbjct: 7407 NV--LDKPGPPAAFDITDVTNESCLLTWNPPRDDGGSKITNYVVERRATDSEVWHKL--S 7462

Query: 1771 PDGEEDTAELQGLRPGSEYTVSVVA-----LHDDMESQPLIGTQSTAIPA-PTDLKFTQV 1824
               ++   +   L P  EY   V A     + + +++ P+        P  PT L+ + +
Sbjct: 7463 STVKDTNFKATKLIPNKEYIFRVAAENMYGVGEPVQASPITAKYQFDPPGPPTRLEPSDI 7522

Query: 1825 TPTSLSAQWTPPN----VQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYE 1880
            T  +++  W  P+      +TGY V     +    ++   +    ++  V GL    KY 
Sbjct: 7523 TKDAVTLTWCEPDDDGGSPITGYWVERLDPDTDKWVRCNKMPVKDTTYRVKGLTNKKKYR 7582

Query: 1881 VSVYALKDTLTSRPAQG-----VVTTLENVSPPRRARVTDATETTITISWRTKTE----- 1930
              V A       +P++      +   ++   PP +  V D  +T++ ++W TK E     
Sbjct: 7583 FRVLAENLAGPGKPSKSTEPILIKDPIDPPWPPGKPTVKDVGKTSVRLNW-TKPEHDGGA 7641

Query: 1931 TITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPV---- 1986
             I  + ++ +       ++         + + GL  G +Y   +  +N    S P     
Sbjct: 7642 KIESYVIEMLKTGTDEWVRVAEGVPTTQHLLPGLMEGQEYSFRVRAVNKAGESEPSEPSD 7701

Query: 1987 VIDASTAIDAPSNLRFLAT---TPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREVV 2039
             +     +  PS  R+L     T N+  + W  P     + IT YI++         + V
Sbjct: 7702 PVLCREKLYPPSPPRWLEVINITKNTADLKWTVPEKDGGSPITNYIVEKRDVRRKGWQTV 7761

Query: 2040 PRPRPGVTEATITGLEPGTEYTIYVIA 2066
                   T+ T+T L  G+ Y   V A
Sbjct: 7762 DTTVKD-TKCTVTPLTEGSLYVFRVAA 7787



 Score = 96.3 bits (238), Expect = 3e-19
 Identities = 294/1454 (20%), Positives = 518/1454 (35%), Gaps = 209/1454 (14%)

Query: 684   IQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSA 743
             I+  G Q + +      + S P+T   +     P  PL      VT +TA    ++W   
Sbjct: 18400 IRTDGGQYILKLSNVGGTKSIPITVKVLDRPGPPEGPL-----KVTGVTAEKCYLAWNPP 18454

Query: 744   SDTVSGFRVEYELSEEGDEPQYLDLPSTATSVN-----IPDLLPGRKYI-----VNVYQI 793
                  G  + + + E+  E   L     +T V      +  LLPG +YI     VN Y I
Sbjct: 18455 LQD-GGANISHYIIEKR-ETSRLSWTQVSTEVQALNYKVTKLLPGNEYIFRVMAVNKYGI 18512

Query: 794   SEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRP----QAPITGYRIVYSPSV 849
              E  E   + + +    P  P  P V  +   S+VV W+RP       I GY I+     
Sbjct: 18513 GEPLESGPVTACNPYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGY-ILEKRDK 18571

Query: 850   EGSSTELNLPETANSVTL--SDLQPGVQYNITIYAVEE---NQESTPVVIQQETTGTPRS 904
             EG        +T   + L  + L  G  Y   + A       + S P V  +        
Sbjct: 18572 EGVRWTKCNKKTLTDLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYR------AC 18625

Query: 905   DTVPSPRDLQFVEVTDV---KVTIMWTPP----ESAVTGYRVDV------------IPVN 945
             D +  P      +VTD     V++ W+ P     + V GY V+V             P  
Sbjct: 18626 DALYPPGPPSNPKVTDTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAADEWTTCTPPTG 18685

Query: 946   LPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLT------AQQ-----T 994
             L G+              VT L     Y F++ A++     +P T      AQ+      
Sbjct: 18686 LQGKQ-----------FTVTKLKENTEYNFRICAINSEGVGEPATLPGSVVAQERIEPPE 18734

Query: 995   TKLDAPTNLQFVNETDSTVLVRWT---PPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKY 1051
              +LDA      V    +T+ +  T    P  ++   +    LT R    Q  V  S +  
Sbjct: 18735 IELDADLRKVVVLRASATLRLFVTIKGRPEPEVKWEKAEGILTDRA---QIEVTSSFTML 18791

Query: 1052  PLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAP 1111
              + N+        +L     +        V     P + +     EV + ++ ++W P  
Sbjct: 18792 VIDNVTRFDSGRYNLTLENNSGSKTAFVNVRVLDSPSAPVNLTIREVKKDSVTLSWEPPL 18851

Query: 1112  RIGFKLGVRPSQGGEAPREVTSDSGSIV----------VSGLTPGVEYVYTIQVLRD--- 1158
               G   G + +      RE T  + + +          +  L  G  Y + +    +   
Sbjct: 18852 IDG---GAKITNYIVEKRETTRKAYATITNNCTKTTFRIENLQEGCSYYFRVLASNEYGI 18908

Query: 1159  GQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT---PDITGYRITTTPTNG 1215
             G   +     KV  P  PP  + L  +      T+ WE+  +     ITGY +       
Sbjct: 18909 GLPAETTEPVKVSEPPLPPGRVTL-VDVTRNTATIKWEKPESDGGSKITGYVVEMQTKGS 18967

Query: 1216  QQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPEVPQLTDLSF 1275
             ++ ++  +V   +    T   L+ G EY   V  V +   S P     +P + +  ++  
Sbjct: 18968 EKWSTCTQVKTLE---ATISGLTAGEEYVFRVAAVNEKGRSDP-RQLGVPVIARDIEIK- 19022

Query: 1276  VDITDSSIGLRWTPLNSSTIIGYRITVVAAG----------EGIPIFEDFVDSSVGYYTV 1325
                   S+ L +   N       +I V   G          +G  + E    +     TV
Sbjct: 19023 -----PSVELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTV 19077

Query: 1326  TGL--EPGIDYDISVITLI----NGGESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTWA 1379
             T L  +     D+    L      G  + P T+       PP  +R   +  D++ ++W 
Sbjct: 19078 TSLSIKEASKEDVGTYELCVSNSAGSITVPITIIVLDRPGPPGPIRIDEVSCDSITISWN 19137

Query: 1380  PPP---SIDLTNFLVRYSPVKNEEDVAE---LSISPSDNAVVLTNLLPGTEYVVSVSS-- 1431
             PP       ++N++V     K E        +S + +  ++ +  L  G+EY   V +  
Sbjct: 19138 PPEYDGGCQISNYIVE----KKETTSTTWHIVSQAVARTSIKIVRLTTGSEYQFRVCAEN 19193

Query: 1432  ---VYEQHESTPLRGRQKTGLDSPTGI-DFSDITANSFTVHWIAP----RATITGYRIRH 1483
                     ES+ +          P G       T ++  V W  P     + + GY + +
Sbjct: 19194 RYGKSSYSESSAVVAEYPFSPPGPPGTPKVVHATKSTMLVTWQVPVNDGGSRVIGYHLEY 19253

Query: 1484  HPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN----GREESPLLIGQQSTVS 1539
                      + +++  +   + ++ L  G  Y   + A N    G+              
Sbjct: 19254 KERSSILWSKANKILIADTQMKVSGLDEGLMYEYRVYAENIAGIGKCSKSCEPVPARDPC 19313

Query: 1540  DVPRDLEVVAATPTSLLISWDAP----AVTVRYYRITYGETGGNSPVQEFTVPGSKSTAT 1595
             D P   EV   T  S+ + W  P       +  Y +   E      ++       ++   
Sbjct: 19314 DPPGQPEVTNITRKSVSLKWSKPHYDGGAKITGYIVERRELPDGRWLKCNYTNIQETYFE 19373

Query: 1596  ISGLKPGVDYTITVYAVTGRGD-SPASSKPISINYRTEIDKPSQMQVTDVQDNSI--SVK 1652
             ++ L     Y   V+A       S  S     I  + +++ P  M     +D  +  + +
Sbjct: 19374 VTELTEDQRYEFRVFARNAADSVSEPSESTGPIIVKDDVEPPRVMMDVKFRDVIVVKAGE 19433

Query: 1653  WLPSSSPVTG--YRVTTTPKNG---PGPTKTKTAGPD-QTEMTIEGL--QPTVEYVVSVY 1704
              L  ++ + G    V +  K+G       +T+    D  T +T++    + T +YV+++ 
Sbjct: 19434 VLKINADIAGRPLPVISWAKDGIEIEERARTEIISTDNHTLLTVKDCIRRDTGQYVLTL- 19492

Query: 1705  AQNPSGESQPLVQTAVTNIDRPKG--LAFTDVDVDSIKIAWESPQ----GQVSRYRVTYS 1758
              +N +G     V   V +   P    L    +  +   ++W  PQ      +  Y V   
Sbjct: 19493 -KNVAGTRSVAVNCKVLDKPGPPAGPLEINGLTAEKCSLSWGRPQEDGGADIDYYIV--- 19548

Query: 1759  SPEDGIHELFPAPDGE--EDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPA- 1815
                +  H  +   +GE    + ++  L  G+EY   V  ++     +PL   +S AI A 
Sbjct: 19549 EKRETSHLAWTICEGELQMTSCKVTKLLKGNEYIFRVTGVNKYGVGEPL---ESVAIKAL 19605

Query: 1816  --------PTDLKFTQVTPTSLSAQWTPP----NVQLTGYRVRVTPKEKTGPMKEINLAP 1863
                     PT L+ T VT  S++  W+ P      +++GY +    K     ++      
Sbjct: 19606 DPFTVPSPPTSLEITSVTKESMTLCWSRPESDGGSEISGYIIERREKNSLRWVRVNKKPV 19665

Query: 1864  DSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQ--GVVTTLENV---SPPRRARVTDATE 1918
                 V  +GL    +YE  VYA      S P++   ++   + V   SPP + ++ D+ +
Sbjct: 19666 YDLRVKSTGLREGCEYEYRVYAENAAGLSLPSETSPLIRAEDPVFLPSPPSKPKIVDSGK 19725

Query: 1919  TTITISWRTKT----ETITGFQVD---AVPANGQTPIQRTIKPDVRSYTITGLQPGTDYK 1971
             TTITI+W          ITG+ V+   +   + +T IQ     +   YTI+GL  G +Y 
Sbjct: 19726 TTITIAWVKPLFDGGAPITGYTVEYKKSDDTDWKTSIQSLRGTE---YTISGLTTGAEYV 19782

Query: 1972  IYLYTLNDNARSSP 1985
               + ++N    S P
Sbjct: 19783 FRVKSVNKVGASDP 19796



 Score = 95.5 bits (236), Expect = 6e-19
 Identities = 319/1473 (21%), Positives = 540/1473 (36%), Gaps = 232/1473 (15%)

Query: 777   IPDLLPGRKYIVNVYQISEDG--EQSLILSTSQTTAPDAPPD------PTVDQVDDTSIV 828
             + DL+ G +Y   V  ++  G  + S  +       PD PP         V++  + +IV
Sbjct: 9706  VEDLVEGGEYEFRVKAVNAAGVSKPSATVGPCDCQRPDMPPSIDLKEFMEVEEGTNVNIV 9765

Query: 829   VR----------WSR--PQAPITGYRIVYSPSVE----GSSTELNLPETANSVTLSDLQP 872
              +          W +  P+ P     ++Y   V       +  L +P++  S T      
Sbjct: 9766  AKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDT------ 9819

Query: 873   GVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE- 931
             G+    TI AV  N  +    ++    G P     P    ++F  V+  ++T+ W PP+ 
Sbjct: 9820  GLY---TITAVN-NLGTASKEMRLNVLGRPGPPVGP----IKFESVSADQMTLSWFPPKD 9871

Query: 932   ---SAVTGYRVDVIPVNLPG-EHGQRLPISRNTFAEVTGLSPGVTYYFKVFA-----VSH 982
                S +T Y ++    N     H    P  +     +  L  G  Y F++ A     +  
Sbjct: 9872  DGGSKITNYVIEKREANRKTWVHVSSEP--KECTYTIPKLLEGHEYVFRIMAQNKYGIGE 9929

Query: 983   GRESKPLTAQQTTKLD-APTNLQFVNETDSTVLVRWTPPR----AQITGYRLTVGLTRRG 1037
               +S+P TA+    +  AP      + T +++ V W  P     + +TGY L +  T   
Sbjct: 9930  PLDSEPETARNLFSVPGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPVTGYWLEMKDTTSK 9989

Query: 1038  QPRQYNVGPSVS-----KYPLRNLQPASEYTVSLVAIKGNQESPK------ATGVFTTLQ 1086
             + ++ N  P  +      Y +  L   S+Y   + AI      P       AT       
Sbjct: 9990  RWKRVNRDPIKAMTLGVSYKVTGLIEGSDYQFRVYAINAAGVGPASLPSDPATARDPIAP 10049

Query: 1087  PGSSIPPYNTEVTETTIVITWTPAPRIGFKLG----VRPSQGGEAPREVTSDSG----SI 1138
             PG   P   T+ T+++  + W+P  + G        V   + G+   E   D       +
Sbjct: 10050 PGPPFPKV-TDWTKSSADLEWSPPLKDGGSKVTGYIVEYKEEGKEEWEKGKDKEVRGTKL 10108

Query: 1139  VVSGLTPGVEYVYTIQVLRD---GQERDAPIVNKVVTPLSPPTNLHLEANP-DTGVLTVS 1194
             VV+GL  G  Y + ++ +     G+  +   V ++   L  P +L L+A+  D  V+   
Sbjct: 10109 VVTGLKEGAFYKFRVRAVNIAGIGEPGEVTDVIEMKDRLVSP-DLQLDASVRDRIVVHAG 10167

Query: 1195  WERSTTPDITGYRITTTPTNGQQGNSLEEVV---HADQSSCTFDNLSPGLEYNVSVYTVK 1251
                     ++G    T   N  +    +E      A  SS    N     +    VY++ 
Sbjct: 10168 GVIRIIAYVSGKPPPTVTWNMNERTLPQEATIETTAISSSMVIKNCQRSHQ---GVYSLL 10224

Query: 1252  DDKESVPISDTIIPEV-----PQLTDLSFVDITDSSIGLRW-TPLNS--STIIGYRITVV 1303
                E+     TII +V     P  T     ++T+ S  L W +P +   S I  Y I   
Sbjct: 10225 AKNEAGERKKTIIVDVLDVPGPVGTPFLAHNLTNESCKLTWFSPEDDGGSPITNYVIEKR 10284

Query: 1304  AAGEGI--PIFEDFVDSSVGYYTVTGLEPGIDY--DISVITLINGGESAPTT----LTQQ 1355
              +      P+       +    TV GL  G  Y   I+    I  G    T+    + + 
Sbjct: 10285 ESDRRAWTPVTYTVTRQNA---TVQGLIQGKAYFFRIAAENSIGMGPFVETSEALVIREP 10341

Query: 1356  TAVPP-PTDLRFTNIGPDTMRVTWAPPP---SIDLTNFLVRYSPVKNEEDVAELSISPSD 1411
               VP  P DL    +  +T+ +TW PP      ++ N+++    +  E+     + +   
Sbjct: 10342 ITVPERPEDLEVKEVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEKFHKVTNDNLLS 10401

Query: 1412  NAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQ----KTGLDSPT-GIDFSDITANSFT 1466
                 +  L  G  Y   VS+V    +  P    +    K  L  PT  +DF D      T
Sbjct: 10402 RKYTVKGLKEGDTYEYRVSAVNIVGQGKPSFCTKPITCKDELAPPTLHLDFRD----KLT 10457

Query: 1467  VHWIAPRATITGYRIRHHPEHFSGRPR------EDRVPHSRNSITLTNLTPGTEYVVSIV 1520
             +  +     +TG         +SG+P+      +D      +  T    TP T  +  I 
Sbjct: 10458 IR-VGEAFALTG--------RYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATLALEKIK 10508

Query: 1521  ALNGREESPLLIGQQST--------VSDVPRDLEVVA------ATPTSLLISWDAP---- 1562
             A         ++ + ST        V+ V R    V        T   ++ISW  P    
Sbjct: 10509 AKRSDSGKYCVVVENSTGSRKGFCQVNVVDRPGPPVGPVSFDEVTKDYMVISWKPPLDDG 10568

Query: 1563  AVTVRYYRITYGETGGN--SPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDS-P 1619
                +  Y I   E G +   PV   T   +K+T  +S L  G DY   ++A    G S P
Sbjct: 10569 GSKITNYIIEKKEVGKDVWMPV---TSASAKTTCKVSKLLEGKDYIFRIHAENLYGISDP 10625

Query: 1620  ASSKPISINYRTEI-DKPSQMQVTDVQDNSISVKWLP---SSSPVTGY---RVTTTPKNG 1672
               S  +    R  + D P Q  VT+V  +S  V W        P+T Y   +  T  K  
Sbjct: 10626 LVSDSMKAKDRFRVPDAPDQPIVTEVTKDSALVTWNKPHDGGKPITNYILEKRETMSKRW 10685

Query: 1673  PGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQN------PSGESQPL-VQTAVTNIDR 1725
                TK        T+  +  L    +Y   V A+N      PS  S+P+  +  +     
Sbjct: 10686 ARVTKDPIH--PYTKFRVPDLLEGCQYEFRVSAENEIGIGDPSPPSKPVFAKDPIAKPSP 10743

Query: 1726  PKGLAFTDVDVDSIKIAWESPQ----GQVSRYRVTYSSPEDGI-HELFPAPDGEEDTA-E 1779
             P      D   +S+ + W+ P+     ++  Y V Y    D         P+   +T  +
Sbjct: 10744 PVNPEAIDTTCNSVDLTWQPPRHDGGSKILGYIVEYQKVGDEEWRRANHTPESCPETKYK 10803

Query: 1780  LQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTS-LSAQWTPPNV 1838
             + GLR G  Y   V+A++   ES P        +P P  +K     P   L A       
Sbjct: 10804 VTGLRDGQTYKFRVLAVNAAGESDP------AHVPEPVLVKDRLEPPELILDANMAREQH 10857

Query: 1839  QLTGYRVRVT------PKEKTGPMKEINLAPDSSSVVVSGLMVATKYEV--------SVY 1884
                G  +R++      P  K    KE   AP  + + V+   V +K E+         +Y
Sbjct: 10858 IKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARIDVTP--VGSKLEIRNAAHEDGGIY 10915

Query: 1885  AL--KDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTE----TITGFQVD 1938
             +L  ++   S+     V  L+   PPR   V++  + +  ++W+   +     IT + V+
Sbjct: 10916 SLTVENPAGSKTVSVKVLVLDKPGPPRDLEVSEIRKDSCYLTWKEPLDDGGSVITNYVVE 10975

Query: 1939  A--VPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPV-------VID 1989
                V +   +P+  T K   +S+    L  G  Y   +   N   R   V        +D
Sbjct: 10976 RRDVASAQWSPLSATSKK--KSHFAKHLNEGNQYLFRVAAENQYGRGPFVETPKPIKALD 11033

Query: 1990  ASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREVVPRPRPG 2045
                    P +L  +      + + W  P     + ITGY+++Y++ G+  ++ +      
Sbjct: 11034 PLHPPGPPKDLHHVDVDKTEVSLVWNKPDRDGGSPITGYLVEYQEEGT--QDWIKFKTVT 11091

Query: 2046  VTEATITGLEPGTEYTIYVIALKNNQKSEPLIG 2078
               E  +TGL+ G  Y   V       K+E ++G
Sbjct: 11092 NLECVVTGLQQGKTYRFRV-------KAENIVG 11117



 Score = 95.1 bits (235), Expect = 7e-19
 Identities = 312/1572 (19%), Positives = 569/1572 (36%), Gaps = 228/1572 (14%)

Query: 616   ITETPSQPNSHPIQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLK 672
             +T T     S  + W  P+    S +  Y++  +PK +  +W         N+  + GL 
Sbjct: 17847 VTLTDVSQTSASLMWEKPEHDGGSRVLGYVVEMQPKGTE-KWSIVAESKVCNA-VVTGLS 17904

Query: 673   PGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETT---PFSP--LVATSES 727
              G  Y+ ++ +  + G  +             PV +  +T + +   PF+   + A  + 
Sbjct: 17905 SGQEYQFRVKAYNEKGKSD-------PRVLGVPVIAKDLTIQPSLKLPFNTYSIQAGEDL 17957

Query: 728   VTEITASSFV---VSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGR 784
               EI         +SWV   + +              +   +++  TATS  +  +  G 
Sbjct: 17958 KIEIPVIGRPRPNISWVKDGEPLK-------------QTTRVNVEETATST-VLHIKEGN 18003

Query: 785   KYIVNVYQISED---GEQSLILSTSQTTAPDAPPDPT-VDQVDDTSIVVRWSRPQ----A 836
             K     Y ++     G  +  LS      P  P  P   D+V    +V+ W  P      
Sbjct: 18004 KDDFGKYTVTATNSAGTATENLSVIVLEKPGPPVGPVRFDEVSADFVVISWEPPAYTGGC 18063

Query: 837   PITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQ 896
              I+ Y +    +   +   ++      ++ ++ L+ G +Y   I+A     +S P+  + 
Sbjct: 18064 QISNYIVEKRDTTTTTWHMVSATVARTTIKITKLKTGTEYQFRIFAENRYGKSAPLDSKA 18123

Query: 897   ETTGTPRSDTVPSPRDLQFV-EVTDVKVTIMWTPPES----AVTGYRVDVIPVN-LPGEH 950
                  P  +  P P    FV  ++  ++ + W  P +     + GY ++    N +    
Sbjct: 18124 VIVQYPFKE--PGPPGTPFVTSISKDQMLVQWHEPVNDGGTKIIGYHLEQKEKNSILWVK 18181

Query: 951   GQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQT----TKLDAPTNLQFV 1006
               + PI    F + TGL  G+ Y FKV A +     KP    +        D P   + +
Sbjct: 18182 LNKTPIQDTKF-KTTGLDEGLEYEFKVSAENIVGIGKPSKVSECFVARDPCDPPGRPEAI 18240

Query: 1007  NETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSV-SKYPLRNLQPASE 1061
               T + V ++W  P     ++ITGY +       G+  + +    + +++ +  L     
Sbjct: 18241 VITRNNVTLKWKKPAYDGGSKITGYIVEKKDLPDGRWMKASFTNVLETEFTVSGLVEDQR 18300

Query: 1062  YTVSLVA--IKGNQESPK-ATGVFTTLQ----PGSSIPPYNTEVT-----ETTIV---IT 1106
             Y   ++A    GN   P  ++G  T       P +S+ P   +V      ET ++   I 
Sbjct: 18301 YEFRVIARNAAGNFSEPSDSSGAITARDEIDAPNASLDPKYKDVIVVHAGETFVLEADIR 18360

Query: 1107  WTPAPRIGFKLGVRPSQGGEAPREVTS--DSGSIVVSGL--TPGVEYVYTIQVLRDGQER 1162
               P P + +    +  +   A  E+ S     ++VV     T G +Y+  +++   G  +
Sbjct: 18361 GKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQYI--LKLSNVGGTK 18418

Query: 1163  DAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWE---RSTTPDITGYRITTTPTNGQQGN 1219
               PI  KV+    PP               ++W    +    +I+ Y I    T+     
Sbjct: 18419 SIPITVKVLDRPGPPEGPLKVTGVTAEKCYLAWNPPLQDGGANISHYIIEKRETSRLSWT 18478

Query: 1220  SLEEVVHADQSSCTFDNLSPGLEY-----NVSVYTVKDDKESVPIS---------DTIIP 1265
              +   V A     T   L PG EY      V+ Y + +  ES P++             P
Sbjct: 18479 QVSTEVQALNYKVT--KLLPGNEYIFRVMAVNKYGIGEPLESGPVTACNPYKPPGPPSTP 18536

Query: 1266  EVPQLTDLSFV-----DITDSSI-------------GLRWTPLNSSTIIGYRITVVAAGE 1307
             EV  +T  S V      + D                G+RWT  N  T+   R+ V    E
Sbjct: 18537 EVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDKEGVRWTKCNKKTLTDLRLRVTGLTE 18596

Query: 1308  GIPI-FEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAVPPPTDLRF 1366
             G    F    +++ G    +  EP + Y         G               PP++ + 
Sbjct: 18597 GHSYEFRVAAENAAGVGEPS--EPSVFYRACDALYPPG---------------PPSNPKV 18639

Query: 1367  TNIGPDTMRVTWAPP---PSIDLTNFLVRYSPVKNEE-DVAELSISPSDNAVVLTNLLPG 1422
             T+    ++ + W+ P       +  ++V       +E                +T L   
Sbjct: 18640 TDTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAADEWTTCTPPTGLQGKQFTVTKLKEN 18699

Query: 1423  TEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGY-RI 1481
             TEY   + ++  +    P                  ++ A+   V  +   AT+  +  I
Sbjct: 18700 TEYNFRICAINSEGVGEPATLPGSVVAQERIEPPEIELDADLRKVVVLRASATLRLFVTI 18759

Query: 1482  RHHPEHFSGRPREDRVPHSRNSITLT---------NLTPGTEYVVSIVALNGREESPLLI 1532
             +  PE      + + +   R  I +T         N+T       ++   N        +
Sbjct: 18760 KGRPEPEVKWEKAEGILTDRAQIEVTSSFTMLVIDNVTRFDSGRYNLTLENNSGSKTAFV 18819

Query: 1533  GQQSTVS-DVPRDLEVVAATPTSLLISWDAPAVT----VRYYRITYGETGGNSPVQEFTV 1587
               +   S   P +L +      S+ +SW+ P +     +  Y +   ET   +     T 
Sbjct: 18820 NVRVLDSPSAPVNLTIREVKKDSVTLSWEPPLIDGGAKITNYIVEKRETTRKA-YATITN 18878

Query: 1588  PGSKSTATISGLKPGVDYTITVYAVT--GRGDSPASSKPISINYRTEIDKPSQMQVTDVQ 1645
               +K+T  I  L+ G  Y   V A    G G    +++P+ ++       P ++ + DV 
Sbjct: 18879 NCTKTTFRIENLQEGCSYYFRVLASNEYGIGLPAETTEPVKVSEPPL--PPGRVTLVDVT 18936

Query: 1646  DNSISVKW-LPSS---SPVTGYRVTTTPKNGPGPTKTKTAGPDQT-EMTIEGLQPTVEYV 1700
              N+ ++KW  P S   S +TGY V    K   G  K  T    +T E TI GL    EYV
Sbjct: 18937 RNTATIKWEKPESDGGSKITGYVVEMQTK---GSEKWSTCTQVKTLEATISGLTAGEEYV 18993

Query: 1701  VSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVD-SIKIAWESPQGQVSRYRVTYSS 1759
               V A N  G S P  Q  V  I R       D+++  S+++ + +   + +R ++    
Sbjct: 18994 FRVAAVNEKGRSDPR-QLGVPVIAR-------DIEIKPSVELPFHTFNVK-AREQLKIDV 19044

Query: 1760  PEDGIHELFP--APDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQ-------- 1809
             P  G  +       DG+    E   +   S  TV+ +++ +   S+  +GT         
Sbjct: 19045 PFKGRPQATVNWRKDGQT-LKETTRVNVSSSKTVTSLSIKE--ASKEDVGTYELCVSNSA 19101

Query: 1810  -STAIPA----------PTDLKFTQVTPTSLSAQWTPPNV----QLTGYRVRVTPKEKTG 1854
              S  +P           P  ++  +V+  S++  W PP      Q++ Y V    KE T 
Sbjct: 19102 GSITVPITIIVLDRPGPPGPIRIDEVSCDSITISWNPPEYDGGCQISNYIVE--KKETTS 19159

Query: 1855  PMKEI-NLAPDSSSVVVSGLMVATKYEVSVYAL----KDTLTSRPAQGVVTTLENVSPPR 1909
                 I + A   +S+ +  L   ++Y+  V A     K + +   A           PP 
Sbjct: 19160 TTWHIVSQAVARTSIKIVRLTTGSEYQFRVCAENRYGKSSYSESSAVVAEYPFSPPGPPG 19219

Query: 1910  RARVTDATETTITISWRTKT----ETITGFQVDAVPANG--QTPIQRTIKPDVRSYTITG 1963
               +V  AT++T+ ++W+         + G+ ++    +    +   + +  D +   ++G
Sbjct: 19220 TPKVVHATKSTMLVTWQVPVNDGGSRVIGYHLEYKERSSILWSKANKILIADTQ-MKVSG 19278

Query: 1964  LQPGTDYKIYLYTLN----DNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPR- 2018
             L  G  Y+  +Y  N         S   + A    D P        T  S+ + W  P  
Sbjct: 19279 LDEGLMYEYRVYAENIAGIGKCSKSCEPVPARDPCDPPGQPEVTNITRKSVSLKWSKPHY 19338

Query: 2019  ---ARITGYIIK 2027
                A+ITGYI++
Sbjct: 19339 DGGAKITGYIVE 19350



 Score = 94.7 bits (234), Expect = 1e-18
 Identities = 315/1607 (19%), Positives = 572/1607 (35%), Gaps = 282/1607 (17%)

Query: 628  IQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISI 684
            + W  P+    + I  Y++    K     W           + + GL  G  Y  ++ ++
Sbjct: 7630 LNWTKPEHDGGAKIESYVIEML-KTGTDEWVRVAEGVPTTQHLLPGLMEGQEYSFRVRAV 7688

Query: 685  QQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSAS 744
             + G  E +              S+ V      + P       V  IT ++  + W +  
Sbjct: 7689 NKAGESEPSE------------PSDPVLCREKLYPPSPPRWLEVINITKNTADLKW-TVP 7735

Query: 745  DTVSGFRVEYELSEEGDEP----QYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGE-- 798
            +   G  +   + E+ D      Q +D     T   +  L  G  Y+  V   +  G+  
Sbjct: 7736 EKDGGSPITNYIVEKRDVRRKGWQTVDTTVKDTKCTVTPLTEGSLYVFRVAAENAIGQSD 7795

Query: 799  ----QSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ----APITGYRIVYSPSVE 850
                +  +L+    T P  P    V  V    + ++W  P+     PI  Y I     + 
Sbjct: 7796 YTEIEDSVLAKDTFTTPGPPYALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKERL- 7854

Query: 851  GSSTELNLPETAN---SVTLSDLQPGVQYNITIYAVEEN-----QESTPVVIQQETTGTP 902
              +  +   +TA    +  ++D+  G +    + A  E       E T ++  ++ T  P
Sbjct: 7855 -GTRWVKAGKTAGPDCNFRVTDVIEGTEVQFQVRAENEAGVGHPSEPTEILSIEDPTSPP 7913

Query: 903  RSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPVNLPGEHGQRL---P 955
                   P DL   +     + I W PPE    S + GY V++ PV    E   R+   P
Sbjct: 7914 SP-----PLDLHVTDAGRKHIAIAWKPPEKNGGSPIIGYHVEMCPVGT--EKWMRVNSRP 7966

Query: 956  ISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLV 1015
            I    F    G+ P   Y  +V AV+    S+P    +      P     ++     ++V
Sbjct: 7967 IKDLKFKVEEGVVPDKEYVLRVRAVNAIGVSEPSEISENVVAKDPDCKPTIDLETHDIIV 8026

Query: 1016 RWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPL-RNLQPASEYTVSLVAIKGNQE 1074
                    I G +L++ +  R  P      P+VS +   + ++ +   T+    I  + E
Sbjct: 8027 --------IEGEKLSIPVPFRAVPV-----PTVSWHKDGKEVKASDRLTMKNDHISAHLE 8073

Query: 1075 SPKAT----GVFT-TLQP--GSSIPPYN---------------TEVTETTIVITWTP--- 1109
             PK+     G++T TL+   GS+    N               +++T+++  +TW P   
Sbjct: 8074 VPKSVRADAGIYTITLENKLGSATASINVKVIGLPGPCKDIKASDITKSSCKLTWEPPEF 8133

Query: 1110 ---APRIGFKLGVRPSQGGEAPREVTSDSGSI--VVSGLTPGVEYVYTIQVLRD-GQERD 1163
                P + + L  R + G      V S    +   V  L P  EY + ++ +   G    
Sbjct: 8134 DGGTPILHYVLERREA-GRRTYIPVMSGENKLSWTVKDLIPNGEYFFRVKAVNKVGGGEY 8192

Query: 1164 APIVNKVVT-----PLSPPTNLHLEANPDTGVLTVSWERSTTPD---ITGYRITTTPTNG 1215
              + N V+      P  PP ++ +  NP    +T++W+         I GY I       
Sbjct: 8193 IELKNPVIAQDPKQPPDPPVDVEVH-NPTAEAMTITWKPPLYDGGSKIMGYIIEKIAKGE 8251

Query: 1216 QQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYT-----VKDDKESVPISDTIIP-EVPQ 1269
            ++     E +     + T   L  G EY   V       + +   + P +  + P + P+
Sbjct: 8252 ERWKRCNEHL-VPILTYTAKGLEEGKEYQFRVRAENAAGISEPSRATPPTKAVDPIDAPK 8310

Query: 1270 LTDLSFVDIT-------DSSIG------LRWTPLNSSTIIGYRITVVAA-------GEGI 1309
            +   + +++        D+SI       + W   + + I+   I   AA       GE +
Sbjct: 8311 VILRTSLEVKRGDEIALDASISGSPYPTITWIK-DENVIVPEEIKKRAAPLVRRRKGE-V 8368

Query: 1310 PIFEDFVDSSVGYYTVTGLEPGI-----------DYDISVITLIN--GGESAPTTLTQQT 1356
               E FV       ++   + G            D+ + +I + N  G   AP T++   
Sbjct: 8369 QEEEPFVLPLTQRLSIDNSKKGESQLRVRDSLRPDHGLYMIKVENDHGIAKAPCTVSVLD 8428

Query: 1357 AVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVL 1416
               PP +  F +I   ++   W PP   D  + ++ Y+  K ++        P    +V+
Sbjct: 8429 TPGPPINFVFEDIRKTSVLCKWEPPLD-DGGSEIINYTLEKKDK------TKPDSEWIVV 8481

Query: 1417 TNLLPGTEYVVSVSSVYEQHE------------------STPLRGRQKTG-LDSPTGIDF 1457
            T+ L   +Y  SV+ + E  E                  S PL  +   G  D+P     
Sbjct: 8482 TSTLRHCKY--SVTKLIEGKEYLFRVRAENRFGPGPPCVSKPLVAKDPFGPPDAPDKPIV 8539

Query: 1458 SDITANSFTVHWIAPR---ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTE 1514
             D+T+NS  V W  P+   + I GY +     + +   R ++   +     +  L  G  
Sbjct: 8540 EDVTSNSMLVKWNEPKDNGSPILGYWLEKREVNSTHWSRVNKSLLNALKANVDGLLEGLT 8599

Query: 1515 YVVSIVALN----GREESPLLIGQQSTVSD--------VPRDLEVVAATPTSLLISWDAP 1562
            YV  + A N    G+   P       T  D        +PR   V   + T++ + W+ P
Sbjct: 8600 YVFRVCAENAAGPGKFSPP---SDPKTAHDPISPPGPPIPR---VTDTSSTTIELEWEPP 8653

Query: 1563 AVT----VRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDS 1618
            A      +  Y +     G N   +           T+  ++ G DY + V AV   G+ 
Sbjct: 8654 AFNGGGEIVGYFVDKQLVGTNEWSRCTEKMIKVRQYTVKEIREGADYKLRVSAVNAAGEG 8713

Query: 1619 -PASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTK 1677
             P  ++P+++    E  +P  +++       +SVK           R+       P PTK
Sbjct: 8714 PPGETQPVTV---AEPQEPPAVEL------DVSVKGGIQIMAGKTLRIPAVVTGRPVPTK 8764

Query: 1678 --TKTAGP-DQTEMTIEGLQPTVEYVVS-----------VYAQNPSGESQPLVQTAVTNI 1723
              TK  G  D+  + I+ +    E ++            + A N  G      +  V ++
Sbjct: 8765 VWTKEEGELDKDRVVIDNVGTKSELIIKDALRKDHGRYVITATNSCGSKFAAARVEVFDV 8824

Query: 1724 DRP-KGLAFTDVDVDSIKIAWESPQ----GQVSRYRVTYSSPEDGIHELFPAPDGEEDTA 1778
              P   L     +     + W  P+     +++ + +     +  +H      + E    
Sbjct: 8825 PGPVLDLKPVVTNRKMCLLNWSDPEDDGGSEITGFIIERKDAK--MHTWRQPIETERSKC 8882

Query: 1779 ELQGLRPGSEYTVSVVALH-----DDMESQPLIGTQSTAIP-APTDLKFTQVTPTSLSAQ 1832
            ++ GL  G EY   V+A +       +E  P++       P +P  L +T+ T ++++  
Sbjct: 8883 DITGLLEGQEYKFRVIAKNKFGCGPPVEIGPILAVDPLGPPTSPERLTYTERTKSTITLD 8942

Query: 1833 WTPPNVQ----LTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKD 1888
            W  P       + GY +     +K    +       ++S +V  L     YE  V A+ +
Sbjct: 8943 WKEPRSNGGSPIQGYIIEKRRHDKPDFERVNKRLCPTTSFLVENLDEHQMYEFRVKAVNE 9002

Query: 1889 TLTSRPA--QGVVTTLENVSPPRRARVTDATETTIT-------------------ISWRT 1927
               S P+    VV   + V P  + R++   +T                      I W +
Sbjct: 9003 IGESEPSLPLNVVIQDDEVPPTIKLRLSVRGDTIKVKAGEPVHIPADVTGLPMPKIEW-S 9061

Query: 1928 KTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVV 1987
            K ET+     DA+    +   +   K ++          GT      YT+  + R   V 
Sbjct: 9062 KNETVIEKPTDALQITKEEVSRSEAKTELSIPKAVREDKGT------YTVTASNRLGSVF 9115

Query: 1988 IDASTAI-DAPSNLRFLATT---PNSLLVSWQPP----RARITGYII 2026
             +    + D PS  R LA T     S  ++W  P     + IT Y+I
Sbjct: 9116 RNVHVEVYDRPSPPRNLAVTDIKAESCYLTWDAPLDNGGSEITHYVI 9162



 Score = 93.2 bits (230), Expect = 3e-18
 Identities = 379/1860 (20%), Positives = 656/1860 (35%), Gaps = 386/1860 (20%)

Query: 624   NSHPIQWNAPQPSHISKYILRW---RPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQ 680
             N+  I+W  P     SK I  W   + +N++   KE  +P    +Y + GL  G+ Y+ +
Sbjct: 22483 NAMSIRWEEPYHDGGSKIIGYWVEKKERNTILWVKENKVPCLECNYKVTGLVEGLEYQFR 22542

Query: 681   LISIQQYGHQEVTRFDFTTTSTSTPVTS-NTVTGETTPFSPLVATSESVTEITASSFVVS 739
               ++   G  + +         S P+ + N V     P          VT++T S+  + 
Sbjct: 22543 TYALNAAGVSKASE-------ASRPIMAQNPVDAPGRP---------EVTDVTRSTVSLI 22586

Query: 740   WVSAS----DTVSGFRVEYELSEEGDEPQYLDLPSTATSVN---IPDLLPGRKYIVNVYQ 792
             W + +      V G+ +E +   E  + ++L    T  S N   +  L  G  Y   V  
Sbjct: 22587 WSAPAYDGGSKVVGYIIERKPVSEVGDGRWLKCNYTIVSDNFFTVTALSEGDTYEFRVLA 22646

Query: 793   ISEDGEQSLILSTSQTTAPD------APPDPTVD-QVDDTSIVVRWSRPQAPITGYRIVY 845
              +  G   +I   S++T P       APP   +D ++    + +R         G  +V 
Sbjct: 22647 KNAAG---VISKGSESTGPVTCRDEYAPPKAELDARLHGDLVTIR--------AGSDLVL 22695

Query: 846   SPSVEGS----------STELNLPETANS----------VTLSDLQPGVQYNITIYAVEE 885
               +V G             EL+L E  +           +   D     +Y +T+     
Sbjct: 22696 DAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSGKYTLTVKNASG 22755

Query: 886   NQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDV 941
              +  + +V   ++ G     TV          VT  K T+ W+ P+    + +T Y V+ 
Sbjct: 22756 TKAVSVMVKVLDSPGPCGKLTVS--------RVTQEKCTLAWSLPQEDGGAEITHYIVE- 22806

Query: 942   IPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYY-----------FKVFAVS-HGR----E 985
                        R   SR  +  V G  P ++Y            F+V AV+ +G     E
Sbjct: 22807 -----------RRETSRLNWVIVEGECPTLSYVVTRLIKNNEYIFRVRAVNKYGPGVPVE 22855

Query: 986   SKPLTAQQTTKLDAPTNL-QFVNETDSTVLVRWTPPRA----QITGYRLTVGLTRRGQPR 1040
             S+P+ A+ +  + +P  + + V      ++++WT P +    +I+ Y   V    +   R
Sbjct: 22856 SEPIVARNSFTIPSPPGIPEEVGTGKEHIIIQWTKPESDGGNEISNY--LVDKREKKSLR 22913

Query: 1041  QYNVGPSVSKYPLR----NLQPASEYTVSLVAIK--GNQESPKATGVFTTLQPGSSIPPY 1094
                V      Y  R    +L    +Y   + A+   GN E  +A+   +  +P       
Sbjct: 22914 WTRVNKDYVVYDTRLKVTSLMEGCDYQFRVTAVNAAGNSEPSEASNFISCREP------- 22966

Query: 1095  NTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTP----GVEYV 1150
                        ++TP P         PS    APR V +   SI ++   P    G + V
Sbjct: 22967 -----------SYTPGP---------PS----APRVVDTTKHSISLAWTKPMYDGGTDIV 23002

Query: 1151  -YTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRIT 1209
              Y +++    QE+D     +V          H  A       T+     T PD+      
Sbjct: 23003 GYVLEM----QEKDTDQWYRV----------HTNA-------TIRNTEFTVPDLK----- 23036

Query: 1210  TTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPEVPQ 1269
                  GQ+ +     V+    S          EY+ S+  ++      P+    IP++  
Sbjct: 23037 ----MGQKYSFRVAAVNVKGMS----------EYSESIAEIE------PVERIEIPDLEL 23076

Query: 1270  LTDLSFVDITDSSIGLRWTPLNSSTIIGYRITVVA-AGEGIPIFEDFVDSSVGYYTVTGL 1328
               DL       +   LR       ++ G    V+  + +GI +    +  +   Y++  +
Sbjct: 23077 ADDLKKTVTIRAGASLRLMV----SVSGRPPPVITWSKQGIDLASRAIIDTTESYSLLIV 23132

Query: 1329  EPGIDYDISVITLI---NGGESAPTTLTQQTAVPPPT-DLRFTNIGPDTMRVTWAPPPSI 1384
             +    YD    T+      G+ + T L +    P P   ++   +  D++ +TW  P +I
Sbjct: 23133 DKVNRYDAGKYTIEAENQSGKKSATVLVKVYDTPGPCPSVKVKEVSRDSVTITWEIP-TI 23191

Query: 1385  DLTNFLVRYSPVKNEEDVAE---LSISPSDNAVVLTNLLPGTEYVVSV--SSVY---EQH 1436
             D    +  Y   K E  +     ++   S     ++ L+ GT Y   V   ++Y   E  
Sbjct: 23192 DGGAPVNNYIVEKREAAMRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYGIGEPC 23251

Query: 1437  ESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRP 1492
             E++      +  L  P  ++  D+T ++ T+ W  P     + +TGY +       +G  
Sbjct: 23252 ETSDAVLVSEVPL-VPAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACK---AGTE 23307

Query: 1493  REDRVPHSRNSI---TLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVP-RDLEVV 1548
             R  +V   + ++   T+T+L  G +Y+  I A N +  S      + TV+ V  +DL V+
Sbjct: 23308 RWMKVVTLKPTVLEHTVTSLNEGEQYLFRIRAQNEKGVSE----PRETVTAVTVQDLRVL 23363

Query: 1549  AATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKS---------------- 1592
                  S +          R   +     G   P   +   GSK                 
Sbjct: 23364 PTIDLSTMPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAK 23423

Query: 1593  -TATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQ----MQVTDVQDN 1647
              T   + ++   +YT+ +  VTG      +S+ I +     +DKP      +++ ++   
Sbjct: 23424 LTIRETTIRDTGEYTLELKNVTG-----TTSETIKVII---LDKPGPPTGPIKIDEIDAT 23475

Query: 1648  SISVKWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSV 1703
             SI++ W P      +P++GY V     + PG      +    T      L    EYV  V
Sbjct: 23476 SITISWEPPELDGGAPLSGYVVEQRDAHRPGWLPVSESVTRST-FKFTRLTEGNEYVFRV 23534

Query: 1704  YAQNPSGESQPL------VQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQ----GQVSRY 1753
              A N  G    L       ++++     P+ L   DV  D + + W  P+     QV+ Y
Sbjct: 23535 AATNRFGIGSYLQSEVIECRSSIRIPGPPETLQIFDVSRDGMTLTWYPPEDDGGSQVTGY 23594

Query: 1754  RVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALH------DDMESQPLIG 1807
              V                          GL  G EY   V A++          S+P++ 
Sbjct: 23595 IVERKEVRADRWVRVNKVPVTMTRYRSTGLTEGLEYEHRVTAINARGSGKPSRPSKPIVA 23654

Query: 1808  TQSTAIPA-PTDLKFTQVTPTSLSAQWTPPNVQ----LTGYRVRVTPKEKTGPMKEINLA 1862
                 A P  P + + T  T TS+S  W+ P  +    +TGY + +   ++    K     
Sbjct: 23655 MDPIAPPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTKCNTTP 23714

Query: 1863  PDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQ--GVVTTLENVSPP---------RRA 1911
                    ++ L    +Y   V A        PA+  G V   E +  P            
Sbjct: 23715 TKIREYTLTHLPQGAEYRFRVLACNAGGPGEPAEVPGTVKVTEMLEYPDYELDERYQEGI 23774

Query: 1912  RVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGT--D 1969
              V       +TI  + K      F +      GQ   +R +     ++T   ++     D
Sbjct: 23775 FVRQGGVIRLTIPIKGKP-----FPICKWTKEGQDISKRAMIATSETHTELVIKEADRGD 23829

Query: 1970  YKIYLYTLNDNARSSPVVIDASTAIDAPSN----LRFLATTPNSLLVSWQPPR----ARI 2021
                Y   L +      V I     I +P++    L +      S+ VSW+PP     A I
Sbjct: 23830 SGTYDLVLENKCGKKAVYIKVRV-IGSPNSPEGPLEYDDIQVRSVRVSWRPPADDGGADI 23888

Query: 2022  TGYII-KYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRK 2080
              GYI+ + E P +    +  R R   T   + GL+   EY   V A      S+PL   +
Sbjct: 23889 LGYILERREVPKAAWYTIDSRVRG--TSLVVKGLKENVEYHFRVSAENQFGISKPLKSEE 23946

Query: 2081  KTVQKTPFVTHPGYDTGNGIQLPGTSGQQPSVGQQMIFEEHGFRRTTPPTTATPIRHRPR 2140
                 KTP                                        PP         P 
Sbjct: 23947 PVTPKTPL--------------------------------------NPP--------EPP 23960

Query: 2141  PYPPNVGQEALSQTTISWAPFQD-----TSEYIISCHPVGTDEEPLQFRVPGTSTSATLT 2195
               PP V     S  ++SW+  +D      + Y I      TD+     +   T+T  T+T
Sbjct: 23961 SNPPEVLDVTKSSVSLSWSRPKDDGGSRVTGYYIERKETSTDKWVRHNKTQITTTMYTVT 24020

Query: 2196  GLTRGATYNIIVEALKD---QQRHKVREEVVTVGNSVNEGLNQPTDDSCFDPYTVSHYAV 2252
             GL   A Y   + A  D    +     E VV       +  ++P+     +  ++S  +V
Sbjct: 24021 GLVPDAEYQFRIIAQNDVGLSETSPASEPVV-----CKDPFDKPSQPGELEILSISKDSV 24075

Query: 2253  GDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHDNGVNYKIGEKWDRQGENGQMMSCT 2312
               +WE+    G K   + LG+   + +   S W   N    K     D+Q   G ++  T
Sbjct: 24076 TLQWEKPECDGGK---EILGYWVEYRQSGDSAWKKSNKERIK-----DKQFTIGGLLEAT 24127



 Score = 90.5 bits (223), Expect = 2e-17
 Identities = 317/1530 (20%), Positives = 556/1530 (36%), Gaps = 208/1530 (13%)

Query: 728   VTEITASSFVVSW----VSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPG 783
             +T+I+ +S  +SW          ++G+ VE     +G   +      T T   I  L   
Sbjct: 20404 ITDISKNSVSLSWQQPAFDGGSKITGYIVERRDLPDGRWTKASFTNVTETQFIISGLTQN 20463

Query: 784   RKYIVNVYQISEDGEQSLILSTSQTTAP----DAPPDPTVDQVDDTSIVVRWS-----RP 834
              +Y   V+  +  G    I + S+   P    D+   P +D   + + VV++      + 
Sbjct: 20464 SQYEFRVFARNAVGS---ISNPSEVVGPITCIDSYGGPVIDLPLEYTEVVKYRAGTSVKL 20520

Query: 835   QAPITGYRIVYSPSVEGSSTELNLPETA-----NSVTLSDL--QPGVQYNITIYAVEENQ 887
             +A I+G     +P++E    +  L   A     N+  L+ +  +   + N   Y ++   
Sbjct: 20521 RAGISGKP---APTIEWYKDDKELQTNALVCVENTTDLASILIKDADRLNSGCYELKLRN 20577

Query: 888   E--STPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDV 941
                S    I+ +    P     P    ++F  VT  K+T++W PP     + +T Y V+ 
Sbjct: 20578 AMGSASATIRVQILDKPG----PPGGPIEFKTVTAEKITLLWRPPADDGGAKITHYIVEK 20633

Query: 942   -----IPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTK 996
                  +  ++  EH +   I+       T +  G  Y F+V AV+     +PL +     
Sbjct: 20634 RETSRVVWSMVSEHLEECIIT------TTKIIKGNEYIFRVRAVNKYGIGEPLESDSVVA 20687

Query: 997   LDA-----PTNLQFVNE-TDSTVLVRWTPPRAQ----ITGYRLTVGLTRR-GQPRQYNVG 1045
              +A     P  +  V + T +++ V W+ P A     I+GY L     +  G  +     
Sbjct: 20688 KNAFVTPGPPGIPEVTKITKNSMTVVWSRPIADGGSDISGYFLEKRDKKSLGWFKVLKET 20747

Query: 1046  PSVSKYPLRNLQPASEYTVSLVAIKGNQESP--KATGVFTTLQP-GSSIPPYNTEVTETT 1102
                ++  +  L   S+Y   + A+    + P  + +  +    P     PP    + ++T
Sbjct: 20748 IRDTRQKVTGLTENSDYQYRVCAVNAAGQGPFSEPSEFYKAADPIDPPGPPAKIRIADST 20807

Query: 1103  ---IVITWTP------APRIGFKLGVRPSQGGEAPREVTSDSGSI-----VVSGLTPGVE 1148
                I + W+       +   G+ + +R  QG E      S  G +     VVS L PGV 
Sbjct: 20808 KSSITLGWSKPVYDGGSAVTGYVVEIR--QGEEEEWTTVSTKGEVRTTEYVVSNLKPGVN 20865

Query: 1149  YVYTIQVLRDGQERDAPIVNKVVTP---LSPP---------TNLHLEANPDTGVL----- 1191
             Y + +  +    + +   +N+ V     L  P         T++  +A  D  VL     
Sbjct: 20866 YYFRVSAVNCAGQGEPIEMNEPVQAKDILEAPEIDLDVALRTSVIAKAGEDVQVLIPFKG 20925

Query: 1192  ----TVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSV 1247
                 TV+W +      +  R +   T+     ++ +V   D             +Y +++
Sbjct: 20926 RPPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTG-----------KYILTI 20974

Query: 1248  YTVKDDKESVPISDTIIPEVPQLTDLSFVDITDSSIGLRWTPL---NSSTIIGYRITVVA 1304
                  + +S  +S  ++        L    ++  ++ L W P      S II Y I    
Sbjct: 20975 ENGVGEPKSSTVSVKVLDTPAACQKLQVKHVSRGTVTLLWDPPLIDGGSPIINYVIEKRD 21034

Query: 1305  AGEGIPIFEDFVDSSVGYYTVTGLEPG-IDYDISVITLINGGESAPTTLTQQTA-VPPPT 1362
             A +          SS  +  +   E     + +     I  GE   TT   + A VP P 
Sbjct: 21035 ATKRTWSVVSHKCSSTSFKLIDLSEKTPFFFRVLAENEIGIGEPCETTEPVKAAEVPAPI 21094

Query: 1363  -DLRFTNIGPDTMRVTWAPPP---SIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTN 1418
              DL   +    ++ ++W  P       +T ++V     K E+  +   IS +   + ++ 
Sbjct: 21095 RDLSMKDSTKTSVILSWTKPDFDGGSVITEYVVERKG-KGEQTWSHAGISKTCE-IEVSQ 21152

Query: 1419  LLPGTEYVVSVSSVYEQHESTPLRGRQKT--GLDSPTGIDFSDITANSFTVHWIAPRATI 1476
             L   +     V +  E+  S P+     T   L     +D SDI     TV         
Sbjct: 21153 LKEQSVLEFRVFAKNEKGLSDPVTIGPITVKELIITPEVDLSDIPGAQVTVR-------- 21204

Query: 1477  TGYRIRHHPEHFSGRPRED----------------RVPHSRNSITLT----NLTPGTEYV 1516
              G+ + H    + G+P+                  R   + N ITL+        G +Y 
Sbjct: 21205 IGHNV-HLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGGKYT 21263

Query: 1517  VSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVT----VRYYRIT 1572
             V +     R   P+ +      S     +        S+++SWD P       +  Y I 
Sbjct: 21264 VILDNAVCRIAVPITVITLGPPSKPKGPIRFDEIKADSVILSWDVPEDNGGGEITCYSIE 21323

Query: 1573  YGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDS-PASSKPISINYRT 1631
               ET   +  +      +++T  +  L    +Y   V A    G S P  S  I   ++ 
Sbjct: 21324 KRETSQTN-WKMVCSSVARTTFKVPNLVKDAEYQFRVRAENRYGVSQPLVSSIIVAKHQF 21382

Query: 1632  EID-KPSQMQVTDVQDNSISVKW----LPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQT 1686
              I   P +  + +V  + +S+ W        S VTG+ V    +N     K  T+     
Sbjct: 21383 RIPGPPGKPVIYNVTSDGMSLTWDAPVYDGGSEVTGFHVEKKERNSILWQKVNTSPISGR 21442

Query: 1687  EMTIEGLQPTVEYVVSVYAQNPSGESQPLVQT----AVTNIDRPKGLAFTDVDVDSIKIA 1742
             E    GL   ++Y   VYA+N +G S P   +    AV+ +D P    + DV  ++I + 
Sbjct: 21443 EYRATGLVEGLDYQFRVYAENSAGLSSPSDPSKFTLAVSPVDPPGTPDYIDVTRETITLK 21502

Query: 1743  WESPQGQVSRYRVTYSSPEDGIHELFPA---PDGEEDTAELQGLRPGSEYTVSVVALHDD 1799
             W  P        V YS  +   +E +      D  E    + GL PG  Y   ++A +  
Sbjct: 21503 WNPPLRDGGSKIVGYSIEKRQGNERWVRCNFTDVSECQYTVTGLSPGDRYEFRIIARNAV 21562

Query: 1800  MESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEI 1859
                 P   +QS+ I    D     +       ++    +  +G  +R+    +  P+  +
Sbjct: 21563 GTISP--PSQSSGIIMTRDENVPPIV--EFGPEYFDGLIIKSGESLRIKALVQGRPVPRV 21618

Query: 1860  NLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTT-LENVSPPRRARV-TDAT 1917
                 D   +     M  T    S        T R  +GV T   +N S   +A +     
Sbjct: 21619 TWFKDGVEIEKRMNMEITDVLGSTSLFVRDAT-RDHRGVYTVEAKNASGSAKAEIKVKVQ 21677

Query: 1918  ETTITISWRTKTETITGFQV----DAVPANGQTPIQRTI----------------KPDVR 1957
             +T   +    +   ITG ++    DA   +G  PI   I                K + +
Sbjct: 21678 DTPGKVVGPIRFTNITGEKMTLWWDAPLNDGCAPITHYIIEKRETSRLAWALIEDKCEAQ 21737

Query: 1958  SYTITGLQPGTDYKIYLYTLNDNA-----RSSPVVIDAS-TAIDAPSNLRFLATTPNSLL 2011
             SYT   L  G +Y+  +  +N         S PVV     T  DAP        T NS+ 
Sbjct: 21738 SYTAIKLINGNEYQFRVSAVNKFGVGRPLDSDPVVAQIQYTVPDAPGIPEPSNITGNSIT 21797

Query: 2012  VSWQPPRA----RITGYII-KYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIA 2066
             ++W  P +     I  YI+ + EK  +   +V+ +     T   +TGL  G EY  +V+A
Sbjct: 21798 LTWARPESDGGSEIQQYILERREKKSTRWVKVISKRPISETRFKVTGLTEGNEYEFHVMA 21857

Query: 2067  LKNNQKSEPLIGRKKTVQKTPFVTHPGYDT 2096
              +N     P  G  + ++    V  PG  T
Sbjct: 21858 -ENAAGVGPASGISRLIKCREPVNPPGPPT 21886



 Score = 90.1 bits (222), Expect = 2e-17
 Identities = 348/1626 (21%), Positives = 567/1626 (34%), Gaps = 224/1626 (13%)

Query: 624   NSHPIQWNAPQ---PSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKG--LKPGVVYE 678
             +S  + W  P+    S I+ YI+  R   S   W+   +   +   TIK   LK G  Y+
Sbjct: 15884 DSITLSWGPPKYDGGSSINNYIVEKRD-TSTTTWQ--IVSATVARTTIKACRLKTGCEYQ 15940

Query: 679   GQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVV 738
              ++ +  +YG       + T       V          P +P+V  S      +  S  V
Sbjct: 15941 FRIAAENRYGKSTYLNSEPTVAQYPFKVPG-------PPGTPVVTLS------SRDSMEV 15987

Query: 739   SWVSASDTVSGFRVEYELS-EEGDEPQYLDL---PSTATSVNIPDLLPGRKYI--VNVYQ 792
              W           + Y L  +E +   ++ L   P   T      L  G +Y   V+   
Sbjct: 15988 QWNEPISDGGSRVIGYHLERKERNSILWVKLNKTPIPQTKFKTTGLEEGVEYEFRVSAEN 16047

Query: 793   ISEDGEQSLILSTSQTTAPDAPPD-PTVDQVDDTSIVVRWSRPQ----APITGYRIVYSP 847
             I   G+ S +        P  PP  P    V   S+ ++W +P     + ITGY +    
Sbjct: 16048 IVGIGKPSKVSECYVARDPCDPPGRPEAIIVTRNSVTLQWKKPTYDGGSKITGYIVEKKE 16107

Query: 848   SVEG---SSTELNLPETANSVTLSDLQPGVQYNITIYA------VEENQESTPVVIQQET 898
               EG    ++  N+ +T   VT   L    +Y   + A        E  EST  +  ++ 
Sbjct: 16108 LPEGRWMKASFTNIIDTHFEVT--GLVEDHRYEFRVIARNAAGVFSEPSESTGAITARDE 16165

Query: 899   TGTPRSDTVPSPRDLQFVEVTD---VKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLP 955
                PR    P  +D   V   +   V   I   P  +      +  I  +    +  RL 
Sbjct: 16166 VDPPRISMDPKYKDTIVVHAGESFKVDADIYGKPIPT------IQWIKGDQELSNTARLE 16219

Query: 956   ISRNTFAEVTGLSPGV-----TYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNE-T 1009
             I    FA    +   V      Y  K   V+ G  S  +  +   +   P     ++  T
Sbjct: 16220 IKSTDFATSLSVKDAVRVDSGNYILKAKNVA-GERSVTVNVKVLDRPGPPEGPVVISGVT 16278

Query: 1010  DSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVS 1065
                  + W PP     + I  Y +    T R      +         +  L   +EYT  
Sbjct: 16279 AEKCTLAWKPPLQDGGSDIINYIVERRETSRLVWTVVDANVQTLSCKVTKLLEGNEYTFR 16338

Query: 1066  LVAIKGNQ-----ESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWT-PAPR-----IG 1114
             ++A+         ES         + P +   P  T VT+ ++++ W  PA       +G
Sbjct: 16339 IMAVNKYGVGEPLESEPVVAKNPFVVPDAPKAPEVTTVTKDSMIVVWERPASDGGSEILG 16398

Query: 1115  FKLGVRPSQGGEAPREVTSDSGSIV--VSGLTPGVEYVYTIQVLRD-GQERDAP--IVNK 1169
             + L  R  +G    R      G +   V+GL    +Y + +      G    +P     K
Sbjct: 16399 YVLEKRDKEGIRWTRCHKRLIGELRLRVTGLIENHDYEFRVSAENAAGLSEPSPPSAYQK 16458

Query: 1170  VVTPL---SPPTNLHLEANPDTGVLTVSWERSTTP---DITGYRITTTPTNGQQGNSLEE 1223
                P+    PP N  +     + V  +SW +       +I GY +     +  +      
Sbjct: 16459 ACDPIYKPGPPNNPKVIDITRSSVF-LSWSKPIYDGGCEIQGYIVEKCDVSVGEWTMCTP 16517

Query: 1224  VVHADQSSCTFDNLSPGLEYNVSVYTVKD----DKESVPISDTIIPEVPQLTDLSFVDIT 1279
                 ++++   + L    EYN  +  +      +   VP    I+ E  +  D+      
Sbjct: 16518 PTGINKTNIEVEKLLEKHEYNFRICAINKAGVGEHADVP-GPIIVEEKLEAPDI------ 16570

Query: 1280  DSSIGLRWTPLNSSTIIGYRITVVAAGEGIP----------IFEDFVDSSVGYYTVTGLE 1329
             D  + LR   +N       R+ V   G   P          I +  +      +T   L+
Sbjct: 16571 DLDLELRKI-INIRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTSSFTSLVLD 16629

Query: 1330  PGIDYDISVITLI----NGGESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAPPPSID 1385
                 YD    TL     +G +SA  T+       PP +L+ T I  D++ +TW  PP +D
Sbjct: 16630 NVNRYDSGKYTLTLENSSGTKSAFVTVRVLDTPSPPVNLKVTEITKDSVSITW-EPPLLD 16688

Query: 1386  LTNFLVRYSPVKNE---EDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLR 1442
               + +  Y   K E   +  A +  +   N+  +  L  G  Y   V++  E     P +
Sbjct: 16689 GGSKIKNYIVEKREATRKSYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAENEYGIGLPAQ 16748

Query: 1443  GRQKTGL----DSPTGIDFSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPRE 1494
                   +      P  I   D+T NS ++ W  P     + I  Y +    +H       
Sbjct: 16749 TADPIKVAEVPQPPGKITVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKHSEKWSEC 16808

Query: 1495  DRVPHSRNSITLTNLTPGTEYVVSIVALNGREES-PLLIGQQSTVSDVPRDLEVVAA-TP 1552
              RV   +    +TNLT G EY+  +VA+N +  S P  +       D+  + +V  A + 
Sbjct: 16809 ARVKSLQ--AVITNLTQGEEYLFRVVAVNEKGRSDPRSLAVPIVAKDLVIEPDVKPAFSS 16866

Query: 1553  TSLLISWD----APAVTVRYYRITYGETGGNSPVQEFT---VPGSKSTATIS----GLKP 1601
              S+ +  D     P        IT+ + G   P+++ T   V  S    T+S        
Sbjct: 16867 YSVQVGQDLKIEVPISGRPKPTITWTKDG--LPLKQTTRINVTDSLDLTTLSIKETHKDD 16924

Query: 1602  GVDYTITVYAVTGRGDSPASSKPISINYRTEIDKP----SQMQVTDVQDNSISVKWLP-- 1655
             G  Y ITV  V G+       K  SI   T +DKP      ++  DV   SI++ W P  
Sbjct: 16925 GGQYGITVANVVGQ-------KTASIEIVT-LDKPDPPKGPVKFDDVSAESITLSWNPPL 16976

Query: 1656  --SSSPVTGYRV-----TTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNP 1708
                   +T Y V     TTT  +    T  +T       + +  L+   EY   ++A+N 
Sbjct: 16977 YTGGCQITNYIVQKRDTTTTVWDVVSATVARTT------LKVTKLKTGTEYQFRIFAENR 17030

Query: 1709  SG-----ESQPLVQTAVTNIDRPKGLAF-TDVDVDSIKIAWESPQGQVSRYRVTYSSPED 1762
              G     ES P+V         P G  F T +  DS+ I W  P        + Y     
Sbjct: 17031 YGQSFALESDPIVAQYPYKEPGPPGTPFATAISKDSMVIQWHEPVNNGGSPVIGYHLERK 17090

Query: 1763  GIHELFPAPDGE---EDTA-ELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTD 1818
               + +      +    DT  + Q L  G EY   V A +     +    ++      P D
Sbjct: 17091 ERNSILWTKVNKTIIHDTQFKAQNLEEGIEYEFRVYAENIVGVGKASKNSECYVARDPCD 17150

Query: 1819  LKFT----QVTPTSLSAQWTPP----NVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVV 1870
                T     V    ++ QWT P       +TGY V          MK        +   V
Sbjct: 17151 PPGTPEPIMVKRNEITLQWTKPVYDGGSMITGYIVEKRDLPDGRWMKASFTNVIETQFTV 17210

Query: 1871  SGLMVATKYEVSVYALKDT-LTSRPAQ--GVVTTLENVSPPRRARVTDATETTITISWRT 1927
             SGL    +YE  V A       S+P+   G +T  + V  PR +      +T +  +  T
Sbjct: 17211 SGLTEDQRYEFRVIAKNAAGAISKPSDSTGPITAKDEVELPRISMDPKFRDTIVVNAGET 17270

Query: 1928  KTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQ-PGTDYKIYL------------ 1974
                    F+++A       P    ++ D         +   TD+K  L            
Sbjct: 17271 -------FRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRIDGGQ 17323

Query: 1975  YTLNDN----ARSSPV---VIDASTAIDAPSNLRFLATTPNSLLVSWQPP----RARITG 2023
             Y L  +    ++S PV   V+D     + P  ++    T     ++W PP     + I+ 
Sbjct: 17324 YILRASNVAGSKSFPVNVKVLDRPGPPEGP--VQVTGVTSEKCSLTWSPPLQDGGSDISH 17381

Query: 2024  YIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTV 2083
             Y+++ ++  S     V           +T L  G EY   ++A+      EPL      +
Sbjct: 17382 YVVE-KRETSRLAWTVVASEVVTNSLKVTKLLEGNEYVFRIMAVNKYGVGEPL-ESAPVL 17439

Query: 2084  QKTPFV 2089
              K PFV
Sbjct: 17440 MKNPFV 17445



 Score = 88.2 bits (217), Expect = 9e-17
 Identities = 167/815 (20%), Positives = 297/815 (36%), Gaps = 113/815 (13%)

Query: 1342  INGGESAPTTL-TQQTAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEE 1400
             + G +S P T+       PP   L+ T +  +   + W PP      N        +   
Sbjct: 18414 VGGTKSIPITVKVLDRPGPPEGPLKVTGVTAEKCYLAWNPPLQDGGANISHYIIEKRETS 18473

Query: 1401  DVAELSISPSDNAV--VLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLD------SP 1452
              ++   +S    A+   +T LLPG EY+  V +V +     PL     T  +       P
Sbjct: 18474 RLSWTQVSTEVQALNYKVTKLLPGNEYIFRVMAVNKYGIGEPLESGPVTACNPYKPPGPP 18533

Query: 1453  TGIDFSDITANSFTVHWIAP----RATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTN 1508
             +  + S IT +S  V W  P       I GY +    +      + ++   +   + +T 
Sbjct: 18534 STPEVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDKEGVRWTKCNKKTLTDLRLRVTG 18593

Query: 1509  LTPGTEYVVSIVALN----GREESPLLIGQQSTV---SDVPRDLEVVAATPTSLLISWDA 1561
             LT G  Y   + A N    G    P +  +          P + +V   + +S+ ++W  
Sbjct: 18594 LTEGHSYEFRVAAENAAGVGEPSEPSVFYRACDALYPPGPPSNPKVTDTSRSSVSLAWSK 18653

Query: 1562  PAVTVRYYRITYGETGGNSPVQEFTVPGSKSTA-----------------TISGLKPGVD 1604
             P               G +PV+ + V   ++ A                 T++ LK   +
Sbjct: 18654 PIY------------DGGAPVKGYVVEVKEAAADEWTTCTPPTGLQGKQFTVTKLKENTE 18701

Query: 1605  YTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYR 1664
             Y   + A+   G    ++ P S+  +  I+ P      D++     V  L +S+ +   R
Sbjct: 18702 YNFRICAINSEGVGEPATLPGSVVAQERIEPPEIELDADLR----KVVVLRASATL---R 18754

Query: 1665  VTTTPKNGPGP----TKTKTAGPD--QTEMTIEGLQPTVEYVV-------SVYAQNPSGE 1711
             +  T K  P P     K +    D  Q E+T       ++ V        ++  +N SG 
Sbjct: 18755 LFVTIKGRPEPEVKWEKAEGILTDRAQIEVTSSFTMLVIDNVTRFDSGRYNLTLENNSGS 18814

Query: 1712  SQPLVQTAVTNI-DRPKGLAFTDVDVDSIKIAWESP----QGQVSRYRVTYSSPEDGIHE 1766
                 V   V +    P  L   +V  DS+ ++WE P      +++ Y V         + 
Sbjct: 18815 KTAFVNVRVLDSPSAPVNLTIREVKKDSVTLSWEPPLIDGGAKITNYIVEKRETTRKAYA 18874

Query: 1767  LFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPT----DLKFT 1822
                  +  + T  ++ L+ G  Y   V+A ++     P   T+   +  P      +   
Sbjct: 18875 TI-TNNCTKTTFRIENLQEGCSYYFRVLASNEYGIGLPAETTEPVKVSEPPLPPGRVTLV 18933

Query: 1823  QVTPTSLSAQWTPP----NVQLTGYRVRVTPK--EKTGPMKEINLAPDSSSVVVSGLMVA 1876
              VT  + + +W  P      ++TGY V +  K  EK     ++     +    +SGL   
Sbjct: 18934 DVTRNTATIKWEKPESDGGSKITGYVVEMQTKGSEKWSTCTQVK----TLEATISGLTAG 18989

Query: 1877  TKYEVSVYALKDTLTSRPAQ-GVVTTLENVS-------PPRRARVTDATETTITISWRTK 1928
              +Y   V A+ +   S P Q GV     ++        P     V    +  I + ++ +
Sbjct: 18990 EEYVFRVAAVNEKGRSDPRQLGVPVIARDIEIKPSVELPFHTFNVKAREQLKIDVPFKGR 19049

Query: 1929  TETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQ----PGTDYKIYLYTLNDNARS- 1983
              +    ++ D     GQT  + T      S T+T L        D   Y   ++++A S 
Sbjct: 19050 PQATVNWRKD-----GQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSNSAGSI 19104

Query: 1984  -SPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREV 2038
               P+ I        P  +R    + +S+ +SW PP      +I+ YI++ ++  S    +
Sbjct: 19105 TVPITIIVLDRPGPPGPIRIDEVSCDSITISWNPPEYDGGCQISNYIVEKKETTSTTWHI 19164

Query: 2039  VPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKS 2073
             V +     T   I  L  G+EY   V A     KS
Sbjct: 19165 VSQ-AVARTSIKIVRLTTGSEYQFRVCAENRYGKS 19198



 Score = 86.3 bits (212), Expect = 3e-16
 Identities = 342/1651 (20%), Positives = 590/1651 (35%), Gaps = 266/1651 (16%)

Query: 628   IQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISI 684
             + W+ P+    S I+ +I+  R    +  W++  I    +   I GL  G  Y+ ++I+ 
Sbjct: 8843  LNWSDPEDDGGSEITGFIIE-RKDAKMHTWRQP-IETERSKCDITGLLEGQEYKFRVIAK 8900

Query: 685   QQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWV--- 741
              ++G                PV    +        P      + TE T S+  + W    
Sbjct: 8901  NKFG-------------CGPPVEIGPILAVDPLGPPTSPERLTYTERTKSTITLDWKEPR 8947

Query: 742   -SASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQS 800
              +    + G+ +E    ++ D  +        TS  + +L   + Y   V  ++E GE  
Sbjct: 8948  SNGGSPIQGYIIEKRRHDKPDFERVNKRLCPTTSFLVENLDEHQMYEFRVKAVNEIGESE 9007

Query: 801   LILSTSQTTAPDAPPDPTVD---QVDDTSIVVRWSRP---QAPITGYRIVYSPSVEGSST 854
               L  +     D  P PT+     V   +I V+   P    A +TG  +   P +E S  
Sbjct: 9008  PSLPLNVVIQDDEVP-PTIKLRLSVRGDTIKVKAGEPVHIPADVTGLPM---PKIEWSKN 9063

Query: 855   E--LNLPETANSVTLSDLQPG-VQYNITI-YAVEENQESTPVVIQQETTGTPRS------ 904
             E  +  P  A  +T  ++     +  ++I  AV E++ +  V          R+      
Sbjct: 9064  ETVIEKPTDALQITKEEVSRSEAKTELSIPKAVREDKGTYTVTASNRLGSVFRNVHVEVY 9123

Query: 905   DTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPGEHGQRLPISRNT 960
             D    PR+L   ++      + W  P     S +T Y +D    +      + +    NT
Sbjct: 9124  DRPSPPRNLAVTDIKAESCYLTWDAPLDNGGSEITHYVIDKRDASRKKAEWEEVT---NT 9180

Query: 961   FAE----VTGLSPGVTYYFKV-----FAVSHGRESKPLTAQQTTKLDAPTNL-QFVNETD 1010
               E    +  L P   Y F+V     + +S   +S  +  Q   +L  P    + +  T 
Sbjct: 9181  AVEKRYGIWKLIPNGQYEFRVRAVNKYGISDECKSDKVVIQDPYRLPGPPGKPKVLARTK 9240

Query: 1011  STVLVRWTPP----RAQITGYRLTVGLTRRGQPRQY----------NVGPSVSKYPLRNL 1056
              ++LV WTPP     + ITGY     L +R +   Y           VG    ++ +  L
Sbjct: 9241  GSMLVSWTPPLDNGGSPITGY----WLEKREEGSPYWSRVSRAPITKVGLKGVEFNVPRL 9296

Query: 1057  QPASEYTVSLVAIKG------NQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPA 1110
                 +Y    +AI        ++ S           PG    P   + T+++I + W P 
Sbjct: 9297  LEGVKYQFRAMAINAAGIGPPSEPSDPEVAGDPIFPPGPPSCPEVKDKTKSSISLGWKPP 9356

Query: 1111  PRIGFKLGVRPSQG--GEAPREVTSD------------SGSIVVSGLTPGVEYVYTIQVL 1156
                  K G  P +G   E   E T+D            +   VV  L    +Y + ++ +
Sbjct: 9357  A----KDGGSPIKGYIVEMQEEGTTDWKRVNEPDKLITTCECVVPNLKELRKYRFRVKAV 9412

Query: 1157  RD-GQERDAPIVNKV-VTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPT- 1213
              + G+   +    ++  T +     + ++      ++  +  +   P +   R T   + 
Sbjct: 9413  NEAGESEPSDTTGEIPATDIQEEPEVFIDIGAQDCLVCKAGSQIRIPAVIKGRPTPKSSW 9472

Query: 1214  --NGQQGNSLEEVVH---ADQSSCTFDNLSPGL----------EYNVSVYTVKDDKES-- 1256
               +G+   ++++ VH    D    T +N S  +          +Y+++       K +  
Sbjct: 9473  EFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECKRSHTGKYSITAKNKAGQKTANC 9532

Query: 1257  -VPISDTIIPEVPQLTDLSFVDITDSSIGLRWTPLN---SSTIIGYRITVVAAGEGIPIF 1312
              V + D  +P  P+  DL   DIT  S  L W   +      I GY I      +G    
Sbjct: 9533  RVKVMD--VPGPPK--DLKVSDITRGSCRLSWKMPDDDGGDRIKGYVIEKRTI-DGKAWT 9587

Query: 1313  EDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAV-------PPPTDLR 1365
             +   D     + V  L     Y   V      G   P    Q+T          PP  L+
Sbjct: 9588  KVNPDCGSTTFVVPDLLSEQQYFFRVRAENRFGIGPPVETIQRTTARDPIYPPDPPIKLK 9647

Query: 1366  FTNIGPDTMRVTWAPPPS---IDLTNFLVR---YSPVK---------NEEDVAELSISPS 1410
                I  +T+ ++W PP +     +T+++V    + P           N+ DV EL  +  
Sbjct: 9648  IGLITKNTVHLSWKPPKNDGGSPVTHYIVECLAWDPTGTKKEAWRQCNKRDVEELQFTVE 9707

Query: 1411  DNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGL---DSPTGIDFSDI--TANSF 1465
             D       L+ G EY   V +V     S P            D P  ID  +        
Sbjct: 9708  D-------LVEGGEYEFRVKAVNAAGVSKPSATVGPCDCQRPDMPPSIDLKEFMEVEEGT 9760

Query: 1466  TVHWIA-----PRATITGYRIRH----------HPEHFSGRPREDR----VPHSRNSITL 1506
              V+ +A     P  T+T ++             +  H +    +D     +P SR S T 
Sbjct: 9761  NVNIVAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDT- 9819

Query: 1507  TNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAP---- 1562
                     Y ++ V   G     + +            ++  + +   + +SW  P    
Sbjct: 9820  ------GLYTITAVNNLGTASKEMRLNVLGRPGPPVGPIKFESVSADQMTLSWFPPKDDG 9873

Query: 1563  AVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRG-DSPAS 1621
                +  Y I   E    + V   + P  + T TI  L  G +Y   + A    G   P  
Sbjct: 9874  GSKITNYVIEKREANRKTWVHVSSEP-KECTYTIPKLLEGHEYVFRIMAQNKYGIGEPLD 9932

Query: 1622  SKP-ISINYRTEIDKPSQMQVTDVQDNSISVKW----LPSSSPVTGYRV---TTTPKN-- 1671
             S+P  + N  +    P +  V+ V  NS++V W        SPVTGY +    TT K   
Sbjct: 9933  SEPETARNLFSVPGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPVTGYWLEMKDTTSKRWK 9992

Query: 1672  --GPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSG---ESQPLVQTAVTNIDRP 1726
                  P K  T G       + GL    +Y   VYA N +G    S P       +   P
Sbjct: 9993  RVNRDPIKAMTLG---VSYKVTGLIEGSDYQFRVYAINAAGVGPASLPSDPATARDPIAP 10049

Query: 1727  KGLAF---TDVDVDSIKIAWESP----QGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAE 1779
              G  F   TD    S  + W  P      +V+ Y V Y   E+G  E     D E    +
Sbjct: 10050 PGPPFPKVTDWTKSSADLEWSPPLKDGGSKVTGYIVEYK--EEGKEEWEKGKDKEVRGTK 10107

Query: 1780  L--QGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTP-TSLSAQWTPP 1836
             L   GL+ G+ Y   V A++     +P  G  +  I    ++K   V+P   L A     
Sbjct: 10108 LVVTGLKEGAFYKFRVRAVNIAGIGEP--GEVTDVI----EMKDRLVSPDLQLDASVRDR 10161

Query: 1837  NVQLTGYRVRV-------TPKEKTGPMKEINLAPDSS--SVVVSGLMVATKYEVS---VY 1884
              V   G  +R+        P   T  M E  L  +++  +  +S  MV    + S   VY
Sbjct: 10162 IVVHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEATIETTAISSSMVIKNCQRSHQGVY 10221

Query: 1885  AL--KDTLTSRPAQGVVTTLENVSPPRRARVT-DATETTITISWRTKTE----TITGFQV 1937
             +L  K+    R    +V  L+   P     +  + T  +  ++W +  +     IT + +
Sbjct: 10222 SLLAKNEAGERKKTIIVDVLDVPGPVGTPFLAHNLTNESCKLTWFSPEDDGGSPITNYVI 10281

Query: 1938  DAVPANGQ--TPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLND-------NARSSPVVI 1988
             +   ++ +  TP+  T+    ++ T+ GL  G  Y   +   N            + V+ 
Sbjct: 10282 EKRESDRRAWTPVTYTVTR--QNATVQGLIQGKAYFFRIAAENSIGMGPFVETSEALVIR 10339

Query: 1989  DASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREVVPRPRP 2044
             +  T  + P +L     T N++ ++W PP+    + I  Y+++    G+     V     
Sbjct: 10340 EPITVPERPEDLEVKEVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEKFHKVTNDNL 10399

Query: 2045  GVTEATITGLEPGTEYTIYVIALKNNQKSEP 2075
                + T+ GL+ G  Y   V A+    + +P
Sbjct: 10400 LSRKYTVKGLKEGDTYEYRVSAVNIVGQGKP 10430



 Score = 84.3 bits (207), Expect = 1e-15
 Identities = 134/644 (20%), Positives = 244/644 (37%), Gaps = 79/644 (12%)

Query: 1512  GTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAP----AVTVR 1567
             G +Y++    + G +  P+ +            ++V   T     ++W  P       + 
Sbjct: 17321 GGQYILRASNVAGSKSFPVNVKVLDRPGPPEGPVQVTGVTSEKCSLTWSPPLQDGGSDIS 17380

Query: 1568  YYRITYGETGGNSPVQEFTVPGSK---STATISGLKPGVDYTITVYAVTGRG-DSPASSK 1623
             +Y +   ET   +    +TV  S+   ++  ++ L  G +Y   + AV   G   P  S 
Sbjct: 17381 HYVVEKRETSRLA----WTVVASEVVTNSLKVTKLLEGNEYVFRIMAVNKYGVGEPLESA 17436

Query: 1624  PISINYRTEID-KPSQMQVTDVQDNSISVKW-LPSS---SPVTGYRVTTTPKNGPGPTKT 1678
             P+ +     +   P  ++VT++  +S++V W  P S   S + GY V    ++G    K 
Sbjct: 17437 PVLMKNPFVLPGPPKSLEVTNIAKDSMTVCWNRPDSDGGSEIIGYIVEKRDRSGIRWIKC 17496

Query: 1679  KTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTA-------VTNIDRPKGLAF 1731
                      + + GL    EY   V A+N +G  +P   T        V     P     
Sbjct: 17497 NKRRITDLRLRVTGLTEDHEYEFRVSAENAAGVGEPSPATVYYKACDPVFKPGPPTNAHI 17556

Query: 1732  TDVDVDSIKIAWESP----QGQVSRYRVTYSSPEDGIHELFPAPDGEEDTA-ELQGLRPG 1786
              D   +SI +AW  P      ++  Y V     ++   ++     G   T  E+  L   
Sbjct: 17557 VDTTKNSITLAWGKPIYDGGSEILGYVVEICKADEEEWQIVTPQTGLRVTRFEISKLTEH 17616

Query: 1787  SEYTVSVVALHDDMESQPLIGT-QSTAIPAPTDLKFTQVTPT-SLSAQWTPPNVQLTGYR 1844
              EY + V AL+        +G  ++T++P     +     P   L ++     V   G  
Sbjct: 17617 QEYKIRVCALNK-------VGLGEATSVPGTVKPEDKLEAPELDLDSELRKGIVVRAGGS 17669

Query: 1845  VRVTPKEKTGPMKEINLAPD----SSSVVVSGLMVATKYEVS----------VYALKDTL 1890
              R+    K  P  EI  + +    +  V +   +  T+  +           +  L+++ 
Sbjct: 17670 ARIHIPFKGRPTPEITWSREEGEFTDKVQIEKGVNYTQLSIDNCDRNDAGKYILKLENSS 17729

Query: 1891  TSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKT----ETITGFQVDAVPANGQT 1946
              S+ A   V  L+   PP+   V +  + +  + W          +  + +D   +  + 
Sbjct: 17730 GSKSAFVTVKVLDTPGPPQNLAVKEVRKDSAFLVWEPPIIDGGAKVKNYVIDKRESTRKA 17789

Query: 1947  PIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPV-VIDASTAIDAPS-----NL 2000
                 + K    S+ +  L  G  Y   +   N+     PV  +DA  A + PS      L
Sbjct: 17790 YANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFGVGVPVETVDAVKAAEPPSPPGKVTL 17849

Query: 2001  RFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEP 2056
               ++ T  SL+  W+ P     +R+ GY+++ +  G+    +V   +  V  A +TGL  
Sbjct: 17850 TDVSQTSASLM--WEKPEHDGGSRVLGYVVEMQPKGTEKWSIVAESK--VCNAVVTGLSS 17905

Query: 2057  GTEYTIYVIALKNNQKSE------PLIGRKKTVQ---KTPFVTH 2091
             G EY   V A     KS+      P+I +  T+Q   K PF T+
Sbjct: 17906 GQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKLPFNTY 17949



 Score = 83.6 bits (205), Expect = 2e-15
 Identities = 320/1617 (19%), Positives = 567/1617 (35%), Gaps = 238/1617 (14%)

Query: 628   IQWNAPQPS---HISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISI 684
             + WN P  +    I+ YI++ R   +   W   +      +  +  LK G  Y+ ++ + 
Sbjct: 16970 LSWNPPLYTGGCQITNYIVQKRDTTTTV-WDVVSATVARTTLKVTKLKTGTEYQFRIFAE 17028

Query: 685   QQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSAS 744
              +YG       D        P+ +     E  P     AT+     I+  S V+ W    
Sbjct: 17029 NRYGQSFALESD--------PIVAQYPYKEPGPPGTPFATA-----ISKDSMVIQWHEPV 17075

Query: 745   DTVSGFRVEYELS-EEGDEPQYLDLPSTA---TSVNIPDLLPG-----RKYIVNVYQISE 795
             +      + Y L  +E +   +  +  T    T     +L  G     R Y  N+  + +
Sbjct: 17076 NNGGSPVIGYHLERKERNSILWTKVNKTIIHDTQFKAQNLEEGIEYEFRVYAENIVGVGK 17135

Query: 796   DGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ----APITGYRIVYSPSVEG 851
               + S          P   P+P +  V    I ++W++P     + ITGY +      +G
Sbjct: 17136 ASKNSECYVARDPCDPPGTPEPIM--VKRNEITLQWTKPVYDGGSMITGYIVEKRDLPDG 17193

Query: 852   ---SSTELNLPETANSVTLSDLQPGVQYNITIYA------VEENQESTPVVIQQETTGTP 902
                 ++  N+ ET    T+S L    +Y   + A      + +  +ST  +  ++    P
Sbjct: 17194 RWMKASFTNVIET--QFTVSGLTEDQRYEFRVIAKNAAGAISKPSDSTGPITAKDEVELP 17251

Query: 903   RSDTVPSPRDLQFVEVTDV-----------KVTIMWTPPESAVTGYRVDVIPVNLPGEHG 951
             R    P  RD   V   +              TI W   +  +              E  
Sbjct: 17252 RISMDPKFRDTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEI--------------EES 17297

Query: 952   QRLPISRNTFAEVTGLSPGVT-----YYFKVFAVSHGRESKPLTAQQTTKLDAPTN-LQF 1005
              R  I    F  +  +   +      Y  +   V+ G +S P+  +   +   P   +Q 
Sbjct: 17298 ARCEIKNTDFKALLIVKDAIRIDGGQYILRASNVA-GSKSFPVNVKVLDRPGPPEGPVQV 17356

Query: 1006  VNETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASE 1061
                T     + W+PP     + I+ Y +    T R            +   +  L   +E
Sbjct: 17357 TGVTSEKCSLTWSPPLQDGGSDISHYVVEKRETSRLAWTVVASEVVTNSLKVTKLLEGNE 17416

Query: 1062  YTVSLVAIK--GNQESPKATGVFTT---LQPGSSIPPYNTEVT---ETTIVITWTPAPR- 1112
             Y   ++A+   G  E  ++  V      + PG   PP + EVT   + ++ + W      
Sbjct: 17417 YVFRIMAVNKYGVGEPLESAPVLMKNPFVLPG---PPKSLEVTNIAKDSMTVCWNRPDSD 17473

Query: 1113  -----IGFKLGVRPSQGGE----APREVTSDSGSIVVSGLTPGVEYVYTIQVLRD---GQ 1160
                  IG+ +  R   G        R +T     + V+GLT   EY + +        G+
Sbjct: 17474 GGSEIIGYIVEKRDRSGIRWIKCNKRRITDLR--LRVTGLTEDHEYEFRVSAENAAGVGE 17531

Query: 1161  ERDAPIVNKVVTPL---SPPTNLHLEANPDTGVLTVSWERSTTP---DITGYRITTTPTN 1214
                A +  K   P+    PPTN H+  +     +T++W +       +I GY +     +
Sbjct: 17532 PSPATVYYKACDPVFKPGPPTNAHI-VDTTKNSITLAWGKPIYDGGSEILGYVVEICKAD 17590

Query: 1215  GQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDK--ESVPISDTIIPE----VP 1268
              ++   +        +      L+   EY + V  +      E+  +  T+ PE     P
Sbjct: 17591 EEEWQIVTPQTGLRVTRFEISKLTEHQEYKIRVCALNKVGLGEATSVPGTVKPEDKLEAP 17650

Query: 1269  QLTDLSFVDITDSSIGLRWTPLNSSTII--GYRITVVAAGEGIPIFEDFVDSSVGYYT-V 1325
             +L DL              + L    ++  G    +    +G P  E       G +T  
Sbjct: 17651 EL-DLD-------------SELRKGIVVRAGGSARIHIPFKGRPTPEITWSREEGEFTDK 17696

Query: 1326  TGLEPGIDYD---------------ISVITLINGGESAPTTLTQQTAVPPPTDLRFTNIG 1370
               +E G++Y                I  +   +G +SA  T+       PP +L    + 
Sbjct: 17697 VQIEKGVNYTQLSIDNCDRNDAGKYILKLENSSGSKSAFVTVKVLDTPGPPQNLAVKEVR 17756

Query: 1371  PDTMRVTWAPPPSIDLTNFLVRYSPVKNEED---VAELSISPSDNAVVLTNLLPGTEYVV 1427
              D+  + W PP  ID    +  Y   K E      A +S   S  +  + NL  G  Y  
Sbjct: 17757 KDSAFLVWEPP-IIDGGAKVKNYVIDKRESTRKAYANVSSKCSKTSFKVENLTEGAIYYF 17815

Query: 1428  SVSSVYEQHESTPLR---GRQKTGLDSPTG-IDFSDITANSFTVHWIAPR----ATITGY 1479
              V +  E     P+      +     SP G +  +D++  S ++ W  P     + + GY
Sbjct: 17816 RVMAENEFGVGVPVETVDAVKAAEPPSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLGY 17875

Query: 1480  RIRHHPEHFSGRPREDRVPHSRN-SITLTNLTPGTEYVVSIVALNGREES-PLLIGQQST 1537
              +   P+   G  +   V  S+  +  +T L+ G EY   + A N + +S P ++G    
Sbjct: 17876 VVEMQPK---GTEKWSIVAESKVCNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVI 17932

Query: 1538  VSDVPRDLEVVAATPTSLL-----ISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKS 1592
               D+     +     T  +     +  + P +      I++ + G   P+++ T    + 
Sbjct: 17933 AKDLTIQPSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDG--EPLKQTTRVNVEE 17990

Query: 1593  TAT--ISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKP-SQMQVTDVQDNSI 1649
             TAT  +  +K G       Y VT    +  +++ +S+    +   P   ++  +V  + +
Sbjct: 17991 TATSTVLHIKEGNKDDFGKYTVTATNSAGTATENLSVIVLEKPGPPVGPVRFDEVSADFV 18050

Query: 1650  SVKWLPSS----SPVTGYRV-----TTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYV 1700
              + W P +      ++ Y V     TTT  +    T  +T       + I  L+   EY 
Sbjct: 18051 VISWEPPAYTGGCQISNYIVEKRDTTTTTWHMVSATVARTT------IKITKLKTGTEYQ 18104

Query: 1701  VSVYAQNPSGESQPLVQTAVT-----NIDRPKGLAF-TDVDVDSIKIAWESPQGQVSRYR 1754
               ++A+N  G+S PL   AV          P G  F T +  D + + W  P        
Sbjct: 18105 FRIFAENRYGKSAPLDSKAVIVQYPFKEPGPPGTPFVTSISKDQMLVQWHEPVNDGGTKI 18164

Query: 1755  VTYSSPEDGIHELF-------PAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIG 1807
             + Y   +   + +        P  D +  T    GL  G EY   V A +     +P   
Sbjct: 18165 IGYHLEQKEKNSILWVKLNKTPIQDTKFKTT---GLDEGLEYEFKVSAENIVGIGKPSKV 18221

Query: 1808  TQSTAIPAPTDL----KFTQVTPTSLSAQWTPP----NVQLTGYRVRVTPKEKTGPMKEI 1859
             ++      P D     +   +T  +++ +W  P      ++TGY V          MK  
Sbjct: 18222 SECFVARDPCDPPGRPEAIVITRNNVTLKWKKPAYDGGSKITGYIVEKKDLPDGRWMKAS 18281

Query: 1860  NLAPDSSSVVVSGLMVATKYEVSVYALKDTLT-SRPAQ--GVVTTLENVSPPRRAR---- 1912
                   +   VSGL+   +YE  V A       S P+   G +T  + +  P  +     
Sbjct: 18282 FTNVLETEFTVSGLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARDEIDAPNASLDPKY 18341

Query: 1913  ----VTDATET-TITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQP- 1966
                 V  A ET  +    R K      +  D      +T  +  IK  ++  T+      
Sbjct: 18342 KDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELE-ETAARMEIKSTIQKTTLVVKDCI 18400

Query: 1967  GTDYKIYLYTLND--NARSSPVVIDASTAIDAPSN-LRFLATTPNSLLVSWQPPR----A 2019
              TD   Y+  L++    +S P+ +        P   L+    T     ++W PP     A
Sbjct: 18401 RTDGGQYILKLSNVGGTKSIPITVKVLDRPGPPEGPLKVTGVTAEKCYLAWNPPLQDGGA 18460

Query: 2020  RITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPL 2076
              I+ YII+  +        V      +    +T L PG EY   V+A+      EPL
Sbjct: 18461 NISHYIIEKRETSRLSWTQVSTEVQALNYK-VTKLLPGNEYIFRVMAVNKYGIGEPL 18516



 Score = 82.4 bits (202), Expect = 5e-15
 Identities = 130/589 (22%), Positives = 217/589 (36%), Gaps = 70/589 (11%)

Query: 1596  ISGLKPGVDYTITVYAVTGRG-DSPASSKPI-SINYRTEIDKPSQMQVTDVQDNSISVKW 1653
             ++ L  G +YT  + AV   G   P  S+P+ + N     D P   +VT V  +S+ V W
Sbjct: 16326 VTKLLEGNEYTFRIMAVNKYGVGEPLESEPVVAKNPFVVPDAPKAPEVTTVTKDSMIVVW 16385

Query: 1654  -LPSS---SPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPS 1709
               P+S   S + GY +    K G   T+       +  + + GL    +Y   V A+N +
Sbjct: 16386 ERPASDGGSEILGYVLEKRDKEGIRWTRCHKRLIGELRLRVTGLIENHDYEFRVSAENAA 16445

Query: 1710  GESQPLVQTA-------VTNIDRPKGLAFTDVDVDSIKIAWESP----QGQVSRYRVTYS 1758
             G S+P   +A       +     P      D+   S+ ++W  P      ++  Y V   
Sbjct: 16446 GLSEPSPPSAYQKACDPIYKPGPPNNPKVIDITRSSVFLSWSKPIYDGGCEIQGYIVEKC 16505

Query: 1759  SPEDGIHELFPAPDGEEDT-AELQGLRPGSEYTVSVVAL-------HDDMESQPLIGTQS 1810
                 G   +   P G   T  E++ L    EY   + A+       H D+    ++  + 
Sbjct: 16506 DVSVGEWTMCTPPTGINKTNIEVEKLLEKHEYNFRICAINKAGVGEHADVPGPIIVEEKL 16565

Query: 1811  TAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEK----TGPMKEINLAPDSS 1866
              A     DL+  ++                   + R TP+ K     G +++  +   +S
Sbjct: 16566 EAPDIDLDLELRKIINIRAGGSLR----LFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTS 16621

Query: 1867  SVVVSGLMVATKYEVSVY--ALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITIS 1924
             S     L    +Y+   Y   L+++  ++ A   V  L+  SPP   +VT+ T+ +++I+
Sbjct: 16622 SFTSLVLDNVNRYDSGKYTLTLENSSGTKSAFVTVRVLDTPSPPVNLKVTEITKDSVSIT 16681

Query: 1925  WRTKT----ETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDN 1980
             W          I  + V+   A  ++           S+ I  LQ G  Y   +   N+ 
Sbjct: 16682 WEPPLLDGGSKIKNYIVEKREATRKSYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAENEY 16741

Query: 1981  ARSSPV----VIDASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPG 2032
                 P      I  +     P  +     T NS+ +SW  P     ++I  YI++ +   
Sbjct: 16742 GIGLPAQTADPIKVAEVPQPPGKITVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKH 16801

Query: 2033  SPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQKTPFVTHP 2092
             S       R +    +A IT L  G EY   V+A+    +S+P       V K   V  P
Sbjct: 16802 SEKWSECARVKS--LQAVITNLTQGEEYLFRVVAVNEKGRSDPRSLAVPIVAK-DLVIEP 16858

Query: 2093  GYDTGNGIQLPGTSGQQPSVGQQMIFEEHGFRRTTPPTTATPIRHRPRP 2141
                       P  S     VGQ +  E              PI  RP+P
Sbjct: 16859 DVK-------PAFSSYSVQVGQDLKIE-------------VPISGRPKP 16887



 Score = 78.2 bits (191), Expect = 9e-14
 Identities = 285/1428 (19%), Positives = 490/1428 (34%), Gaps = 237/1428 (16%)

Query: 690   QEVTRFDFTTTSTST---------------PVTSNTVTGET-------------TPFSPL 721
             ++  R +F TT+TST               P+T+  + GE               P  P+
Sbjct: 14735 KQTQRVNFETTATSTILNINECVRSDSGPYPLTARNIVGEVGDVITIQVHDIPGPPTGPI 14794

Query: 722   VATSESVTEITASSFVVSWVSASDT----VSGFRVEYELSEEGDEPQYLDLPSTA--TSV 775
                     E+++     SW    +     +S + VE     + D   +++L +T   T+ 
Sbjct: 14795 -----KFDEVSSDFVTFSWDPPENDGGVPISNYVVEMR---QTDSTTWVELATTVIRTTY 14846

Query: 776   NIPDLLPGRKYIVNV-----YQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVR 830
                 L  G +Y   V     Y +      + I++      P  P  P V  V   S+ + 
Sbjct: 14847 KATRLTTGLEYQFRVKAQNRYGVGPGITSACIVANYPFKVPGPPGTPQVTAVTKDSMTIS 14906

Query: 831   WSRPQA----PITGYRIVYSPSVEGSSTELNLPETANSVTL-------SDLQPGVQYNIT 879
             W  P +    PI GY       VE       L +T +   +       S L  G+ Y   
Sbjct: 14907 WHEPLSDGGSPILGYH------VERKERNGILWQTVSKALVPGNIFKSSGLTDGIAYEFR 14960

Query: 880   IYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESA----VT 935
             + A     +S P    +        D    P  L     T   VT+ W  PE      +T
Sbjct: 14961 VIAENMAGKSKPSKPSEPMLALDPIDPPGKPVPLNITRHT---VTLKWAKPEYTGGFKIT 15017

Query: 936   GYRVDVIPVNLPGEHGQRLPISR---NTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQ 992
              Y V+    +LP     +   S    N F  V+GL+    Y F+V A +      P +  
Sbjct: 15018 SYIVE--KRDLPNGRWLKANFSNILENEFT-VSGLTEDAAYEFRVIAKNAAGAISPPSEP 15074

Query: 993   QTT-----KLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPS 1047
                      ++AP     V   D+ +L            +RL   ++ R  P        
Sbjct: 15075 SDAITCRDDVEAPKIKVDVKFKDTVILKAGE-------AFRLEADVSGRPPPTMEWSKDG 15127

Query: 1048  VSKYPLRNLQ-PASEYTVSLVAIKGNQESPKATGVFTTLQPGSSI-------------PP 1093
                     L+   ++++ +LV  K +          T   PG                PP
Sbjct: 15128 KELEGTAKLEIKIADFSTNLVN-KDSTRRDSGAYTLTATNPGGFAKHIFNVKVLDRPGPP 15186

Query: 1094  YN----TEVTETTIVITW-TPAPRIGFKLGVRPSQGGEAPREVTSDSGSIV------VSG 1142
                   TEVT    V++W  P    G K+     Q  E  R   ++  S V      V+ 
Sbjct: 15187 EGPLAVTEVTSEKCVLSWFPPLDDGGAKIDHYIVQKRETSRLAWTNVASEVQVTKLKVTK 15246

Query: 1143  LTPGVEYVYTIQVLRD---GQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLT-----VS 1194
             L  G EY++ +  +     G+  ++  V   V P  PP       NP+   +T     V 
Sbjct: 15247 LLKGNEYIFRVMAVNKYGVGEPLESEPV-LAVNPYGPPDP---PKNPEVTTITKDSMVVC 15302

Query: 1195  WERSTTP---DITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVK 1251
             W    +    +I  Y +      GQ+     +    D        L+ G EY   +    
Sbjct: 15303 WGHPDSDGGSEIINYIVERRDKAGQRWIKCNKKTLTDLRY-KVSGLTEGHEYEFRIMAEN 15361

Query: 1252  DDKESVP--------ISDTIIPEVPQLTDLSFVDITDSSIGLRWT-PL--NSSTIIGYRI 1300
                 S P          DT+    P   +   +D + SSI + W  P+    S I GY +
Sbjct: 15362 AAGISAPSPTSPFYKACDTVFKPGPP-GNPRVLDTSRSSISIAWNKPIYDGGSEITGYMV 15420

Query: 1301  TVVAAGEGI-PIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAP-----TTLTQ 1354
              +    E    I           YT+TGL    +Y I +  + + G   P     T   +
Sbjct: 15421 EIALPEEDEWQIVTPPAGLKATSYTITGLTENQEYKIRIYAMNSEGLGEPALVPGTPKAE 15480

Query: 1355  QTAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNE------------EDV 1402
                +PP  +L       D  +V      +I     L  + P+K              E +
Sbjct: 15481 DRMLPPEIEL-----DADLRKVV-----TIRACCTLRLFVPIKGRPAPEVKWARDHGESL 15530

Query: 1403  AELSISPSDNAVVL----TNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFS 1458
              + SI  + +  +L     N     +Y+++V +     +S  +  R       P  +   
Sbjct: 15531 DKASIESTSSYTLLIVGNVNRFDSGKYILTVENS-SGSKSAFVNVRVLDTPGPPQDLKVK 15589

Query: 1459  DITANSFTVHWIAPRATITGYRIRHH--PEHFSGRPREDRVPHS--RNSITLTNLTPGTE 1514
             ++T  S T+ W  P     G +I+++   +  S R     V  +  + S  +  L  G  
Sbjct: 15590 EVTKTSVTLTWDPPLLD-GGSKIKNYIVEKRESTRKAYSTVATNCHKTSWKVDQLQEGCS 15648

Query: 1515  YVVSIVALNGREES-PLLIGQQSTVSD---VPRDLEVVAATPTSLLISWDAP----AVTV 1566
             Y   ++A N      P    +    S+    P  + ++  T  S+ +SW+ P       +
Sbjct: 15649 YYFRVLAENEYGIGLPAETAESVKASERPLPPGKITLMDVTRNSVSLSWEKPEHDGGSRI 15708

Query: 1567  RYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPIS 1626
               Y +     G +      TV  ++  ATI+GL  G +Y+  V A   +G S      + 
Sbjct: 15709 LGYIVEMQTKGSDKWATCATVKVTE--ATITGLIQGEEYSFRVSAQNEKGISDPRQLSVP 15766

Query: 1627  INYRTEIDKPS------QMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKT 1680
             +  +  +  P+         V   +D  + V ++   +P   +     P       +T  
Sbjct: 15767 VIAKDLVIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLK-----QTTR 15821

Query: 1681  AGPDQTE----MTIEGL--QPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKG--LAFT 1732
                + TE    +TI+    +    YVV +   N +GE+   +   V +   P    +   
Sbjct: 15822 VNAESTENNSLLTIKDACREDVGHYVVKL--TNSAGEAIETLNVIVLDKPGPPTGPVKMD 15879

Query: 1733  DVDVDSIKIAWESPQ----GQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSE 1788
             +V  DSI ++W  P+      ++ Y V          ++  A      T +   L+ G E
Sbjct: 15880 EVTADSITLSWGPPKYDGGSSINNYIVEKRDTSTTTWQIVSATVART-TIKACRLKTGCE 15938

Query: 1789  YTVSVVALH-----DDMESQPLIGTQSTAIPAPTDLKFTQVTPT-SLSAQWTPP----NV 1838
             Y   + A +       + S+P +      +P P       ++   S+  QW  P      
Sbjct: 15939 YQFRIAAENRYGKSTYLNSEPTVAQYPFKVPGPPGTPVVTLSSRDSMEVQWNEPISDGGS 15998

Query: 1839  QLTGYRVRVTPKEKTGPM-KEINLAP-DSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQ 1896
             ++ GY +    KE+   +  ++N  P   +    +GL    +YE  V A       +P++
Sbjct: 15999 RVIGYHLE--RKERNSILWVKLNKTPIPQTKFKTTGLEEGVEYEFRVSAENIVGIGKPSK 16056

Query: 1897  --GVVTTLENVSPPRRARVTDATETTITISWRTKT----ETITGFQVD 1938
                     +   PP R      T  ++T+ W+  T      ITG+ V+
Sbjct: 16057 VSECYVARDPCDPPGRPEAIIVTRNSVTLQWKKPTYDGGSKITGYIVE 16104



 Score = 75.1 bits (183), Expect = 8e-13
 Identities = 286/1351 (21%), Positives = 472/1351 (34%), Gaps = 234/1351 (17%)

Query: 797   GEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ----APITGYRIVYSPSVEGS 852
             G +++ +       P  P D  V ++   S  + W  P     + IT Y +         
Sbjct: 10924 GSKTVSVKVLVLDKPGPPRDLEVSEIRKDSCYLTWKEPLDDGGSVITNYVVERRDVASAQ 10983

Query: 853   STELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRD 912
              + L+      S     L  G QY   + A  +      V   +             P+D
Sbjct: 10984 WSPLSATSKKKSHFAKHLNEGNQYLFRVAAENQYGRGPFVETPKPIKALDPLHPPGPPKD 11043

Query: 913   LQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPVNLPGEHGQRLPISRNTFAE----V 964
             L  V+V   +V+++W  P+    S +TGY V+        E G +  I   T       V
Sbjct: 11044 LHHVDVDKTEVSLVWNKPDRDGGSPITGYLVEY------QEEGTQDWIKFKTVTNLECVV 11097

Query: 965   TGLSPGVTYYFKVFA---VSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPR 1021
             TGL  G TY F+V A   V  G     +  +   KL  P+    V   +  V+   T  R
Sbjct: 11098 TGLQQGKTYRFRVKAENIVGLGLPDTTIPIECQEKLVPPSVELDVKLIEGLVVKAGTTVR 11157

Query: 1022  --AQITGYRL-TVGLTRRGQPRQYNVGPSV------SKYPLRNL--QPASEYTVSLVAIK 1070
               A I G  + T   T  G   + +   +V      S   ++N   +   EY +++    
Sbjct: 11158 FPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEYQITV---- 11213

Query: 1071  GNQESPKATGVFTTLQ--PGSSIPPYNT-EVTETTIVITWTPAPRIGFKLGVRPSQGGEA 1127
              N    K   V  T+   PG    P N  +VT   + I+W P           P   G +
Sbjct: 11214 SNAAGSKTVAVHLTVLDVPGPPTGPINILDVTPEHMTISWQP-----------PKDDGGS 11262

Query: 1128  P--------REVTSDSGSIVVSG----------LTPGVEYVYTIQV---LRDGQERDA-P 1165
             P        ++   D+  +V SG          L  G EYV+ ++    +  G   D+ P
Sbjct: 11263 PVINYIVEKQDTRKDTWGVVSSGSSKTKLKIPHLQKGCEYVFRVRAENKIGVGPPLDSTP 11322

Query: 1166  IVNK-VVTPLSPPTNLHLEANPDTGVLTVSWERSTTPD---ITGY------------RIT 1209
              V K   +P SPP    +  +      TVSW    +     ITGY            R+ 
Sbjct: 11323 TVAKHKFSPPSPPGK-PVVTDITENAATVSWTLPKSDGGSPITGYYMERREVTGKWVRVN 11381

Query: 1210  TTP--------TNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISD 1261
              TP        T   +GN+ E  V A+       NL+   + + S   +K  +   PI  
Sbjct: 11382 KTPIADLKFRVTGLYEGNTYEFRVFAE-------NLAGLSKPSPSSDPIKACR---PIKP 11431

Query: 1262  TIIPEVPQLTDLSFVDITDSSIGLRWT-PLNS--STIIGYRITVVAAG--EGIPIFEDFV 1316
                P  P+L D S       +  L WT PL+   S I+GY +     G  +   I +D +
Sbjct: 11432 PGPPINPKLKDKS-----RETADLVWTKPLSDGGSPILGYVVECQKPGTAQWNRINKDEL 11486

Query: 1317  DSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAV-----PPPTDLRFTNIGP 1371
                  +  V GL  G +Y   +      GE  P  L +         PP  +L  T    
Sbjct: 11487 IRQCAF-RVPGLIEGNEYRFRIKAANIVGEGEPRELAESVIAKDILHPPEVELDVTCRDV 11545

Query: 1372  DTMRVTWA----------PPPSIDLTN---FLVRYSPVKNEEDV--AELSISPSDNAVVL 1416
              T+RV             P P I  T     LVR   V   +D+   EL I  +  A   
Sbjct: 11546 ITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRA--- 11602

Query: 1417  TNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSP---TGIDFSDITANSFTVHWIAPR 1473
                    +Y++S  +     + + +       LD P     +  +++T  + T+ W  P 
Sbjct: 11603 ----DHGKYIISAKNSSGHAQGSAI----VNVLDRPGPCQNLKVTNVTKENCTISWENPL 11654

Query: 1474  ----ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNG----- 1524
                 + IT + + +   +  G          R  +   NL    EY   + A N      
Sbjct: 11655 DNGGSEITNFIVEYRKPNQKGWSIVASDVTKR--LIKANLLANNEYYFRVCAENKVGVGP 11712

Query: 1525  --REESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYG---ETGGN 1579
                 ++P+L          P +L +     T + + W  P        ++Y       G+
Sbjct: 11713 TIETKTPILAINPIDRPGEPENLHIADKGKTFVYLKWRRPDYDGGSPNLSYHVERRLKGS 11772

Query: 1580  SPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASS--KPISINYRTEIDKPS 1637
                +       K T  +  +   V+  I  + V  + +   S   K   +  + ++ KP 
Sbjct: 11773 DDWERVHKGSIKETHYM--VDRCVENQIYEFRVQTKNEGGESDWVKTEEVVVKEDLQKP- 11829

Query: 1638  QMQVTDVQDNSIS-VKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMT------I 1690
                   V D  +S V  + +   +   R+    +  P P    T   D T++T      I
Sbjct: 11830 ------VLDLKLSGVLTVKAGDTI---RLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKI 11880

Query: 1691  EGLQPTVEYVVSVYAQNPSGE--------SQPLVQTAVTNI-DRP---KGLAFTDVDVDS 1738
             +    + ++ ++   ++  G+        +   V  A  N+ D+P   + L   DV  D 
Sbjct: 11881 DTRADSSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATVNVLDKPGPVRNLKIVDVSSDR 11940

Query: 1739  IKIAWESPQG----QVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSV- 1793
               + W+ P+     ++  Y +     +  +   + A      T   + L  G+EY   V 
Sbjct: 11941 CTVCWDPPEDDGGCEIQNYILEKCETKRMVWSTYSATVLTPGTTVTR-LIEGNEYIFRVR 11999

Query: 1794  ----VALHDDMESQPLIGTQSTAIPA-PTDLKFTQVTPTSLSAQWTPPNVQ----LTGYR 1844
                 +      ES+P+I       P  P   + T+V+   ++  W PP       +TGY 
Sbjct: 12000 AENKIGTGPPTESKPVIAKTKYDKPGRPDPPEVTKVSKEEMTVVWNPPEYDGGKSITGYF 12059

Query: 1845  VRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKD------TLTSRPAQGV 1898
             +    K  T  +     A     + V  L+   +Y+  V A  +      +L SRP    
Sbjct: 12060 LEKKEKHSTRWVPVNKSAIPERRMKVQNLLPDHEYQFRVKAENEIGIGEPSLPSRPVVAK 12119

Query: 1899  VTTLENVSPPRRARVTDATETTITISWRTKT----ETITGFQV-------DAVPANGQTP 1947
                +E   PP   RV D T+ +IT+ W          I G+ V       DA P  G   
Sbjct: 12120 -DPIEPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAPIIGYVVEMRPKIADASPDEGWKR 12178

Query: 1948  IQRTIKPDVRSYTITGLQPGTDYKIYLYTLN 1978
                  +   + +T+T L    +Y+  +   N
Sbjct: 12179 CNAAAQLVRKEFTVTSLDENQEYEFRVCAQN 12209



 Score = 74.3 bits (181), Expect = 1e-12
 Identities = 276/1411 (19%), Positives = 484/1411 (34%), Gaps = 227/1411 (16%)

Query: 814   PPDPTVD--QVDDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTL 867
             PP P  D   +D  +  + W  P     + IT Y +       G         T  S  +
Sbjct: 12622 PPQPPFDISDIDADACSLSWHIPLEDGGSNITNYIVEKCDVSRGDWVTALASVTKTSCRV 12681

Query: 868   SDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPS-PRDLQFVEVTDVKVTIM 926
               L PG +Y   + A      S P+   +     P    VPS P++ +  +V    + + 
Sbjct: 12682 GKLIPGQEYIFRVRAENRFGISEPLTSPKMVAQFPFG--VPSEPKNARVTKVNKDCIFVA 12739

Query: 927   WTPPES----AVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSH 982
             W  P+S     + GY ++    N          + R+T     GL  G+ Y F+++A++ 
Sbjct: 12740 WDRPDSDGGSPIIGYLIERKERNSLLWVKANDTLVRSTEYPCAGLVEGLEYSFRIYALNK 12799

Query: 983   GRESKPL--TAQQTTKL--DAPTNLQFVNETDSTVLVRWTPPR----AQITGYRLTVGLT 1034
                S P   T   T ++  D P   + ++ T STV + W  P+    ++I GY +     
Sbjct: 12800 AGSSPPSKPTEYVTARMPVDPPGKPEVIDVTKSTVSLIWARPKHDGGSKIIGYFVEACKL 12859

Query: 1035  RRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPY 1094
                +  + N  P        +  P  EYT + +  K   +          + P S     
Sbjct: 12860 PGDKWVRCNTAP--------HQIPQEEYTATGLEEKAQYQFRAIARTAVNISPPS----- 12906

Query: 1095  NTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQ 1154
               E ++   ++     PRI   + ++     +A   V  D+   V     P V +     
Sbjct: 12907 --EPSDPVTILAENVPPRIDLSVAMKSLLTVKAGTNVCLDA--TVFGKPMPTVSWKKDGT 12962

Query: 1155  VLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTN 1214
             +L+  +     +   + T       L      D+G  T++ E S+       ++      
Sbjct: 12963 LLKPAEGIKMAMQRNLCT-----LELFSVNRKDSGDYTITAENSSGSKSATIKLKVLDKP 13017

Query: 1215  GQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYT--VKDDKESVPISDTIIPEVPQLTD 1272
             G   +     +++D++  +++   P LE   S  T  + D +E      T  P   Q++ 
Sbjct: 13018 GPPASVKINKMYSDRAMLSWE---PPLEDGGSEITNYIVDKRE------TSRPNWAQVS- 13067

Query: 1273  LSFVDITDSSIGLRWTPLNSSTIIG--YRITVVAA---GEGIPIFEDFVDSSVGYYTVTG 1327
              + V IT  S+           I G  Y+  + A    G G P+F               
Sbjct: 13068 -ATVPITSCSV--------EKLIEGHEYQFRICAENKYGVGDPVFT-------------- 13104

Query: 1328  LEPGIDYDISVITLINGGESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAPPPS---I 1384
              EP I               A           PP     +NI  D M V+W PP      
Sbjct: 13105 -EPAI---------------AKNPYDPPGRCDPPV---ISNITKDHMTVSWKPPADDGGS 13145

Query: 1385  DLTNFLV--RYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLR 1442
              +T +L+  R +   N   V    I   +  +  T L  GTEY   V+++ +     P  
Sbjct: 13146 PITGYLLEKRETQAVNWTKVNRKPII--ERTLKATGLQEGTEYEFRVTAINKAGPGKPSD 13203

Query: 1443  GRQKTGLDSP-------TGIDFSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGR 1491
               +      P             D T +S ++ W  P     + I GY +          
Sbjct: 13204 ASKAAYARDPQYPPGPPAFPKVYDTTRSSVSLSWGKPAYDGGSPIIGYLVEVKRADSDNW 13263

Query: 1492  PREDRVPH-SRNSITLTNLTPGTEYVVSIVALNGREES-PLLIGQQSTVSDV--PRDLEV 1547
              R +   +  +    +T L   T+Y   + A+N    S P  +  +    D+  P + E+
Sbjct: 13264 VRCNLPQNLQKTRFEVTGLMEDTQYQFRVYAVNKIGYSDPSDVPDKHYPKDILIPPEGEL 13323

Query: 1548  VAATPTSLLISWDAPAVTVRYY---------RITYGETGGNSPVQEFTVPGSKSTATISG 1598
              A    +L++      VT+R Y         +IT+ +   N   +      S    T   
Sbjct: 13324 DADLRKTLILR---AGVTMRLYVPVKGRPPPKITWSKPNVNLRDRIGLDIKSTDFDTFLR 13380

Query: 1599  LKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLP--- 1655
              +    Y    Y +T           I +        P  + V ++  +S  V W P   
Sbjct: 13381 CENVNKYDAGKYILTLENSCGKKEYTIVVKVLDTPGPPVNVTVKEISKDSAYVTWEPPII 13440

Query: 1656  -SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQP 1714
                SP+  Y V            T T    +T   +  L+    Y   V+A+N  G   P
Sbjct: 13441 DGGSPIINYVVQKRDAERKS-WSTVTTECSKTSFRVANLEEGKSYFFRVFAENEYGIGDP 13499

Query: 1715  LVQTAVTNIDRPKG----LAFTDVDVDSIKIAWESPQG----QVSRYRVTYSSPEDGIHE 1766
                       +  G    L    V   S  I W+ P      ++  Y V + + E+    
Sbjct: 13500 GETRDAVKASQTPGPVVDLKVRSVSKSSCSIGWKKPHSDGGSRIIGYVVDFLTEENKWQR 13559

Query: 1767  LFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTP 1826
             +  +   +    +L     G EYT  V A +++ E  P        + A  D     V  
Sbjct: 13560 VMKSLSLQYSAKDLT---EGKEYTFRVSAENENGEGTP----SEITVVARDD-----VVA 13607

Query: 1827  TSLSAQWTPPNVQL----TGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVS 1882
               L  +  P    L    + +R+++  K K  P        D        L   T+  V 
Sbjct: 13608 PDLDLKGLPDLCYLAKENSNFRLKIPIKGKPAPSVSWKKGEDP-------LATDTRVSVE 13660

Query: 1883  VYALKDTLTSRPAQ----GVVT-TLENVSPPRRARVT-----------------DATETT 1920
               A+  TL     Q    G  T TL+NV+  +   ++                 + T   
Sbjct: 13661 SSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKEGTISIKVVGKPGIPTGPIKFDEVTAEA 13720

Query: 1921  ITISWRTKTET----ITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYL-- 1974
             +T+ W    +     IT + ++   +     +         ++ +T L  G +Y   +  
Sbjct: 13721 MTLKWAPPKDDGGSEITNYILEKRDSVNNKWVTCASAVQKTTFRVTRLHEGMEYTFRVSA 13780

Query: 1975  ---YTLNDNARSSPVVIDASTAI-DAPSNLRFLATTPNSLLVSWQPPR----ARITGYII 2026
                Y + +  +S P+V      + DAP     +    +S+ ++W  P+    + ITGY +
Sbjct: 13781 ENKYGVGEGLKSEPIVARHPFDVPDAPPPPNIVDVRHDSVSLTWTDPKKTGGSPITGYHL 13840

Query: 2027  KYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIAL------KNNQKSEPLI--- 2077
             ++++  S   +   +    + +  +TGL  G EY   V+A+      K +  SEP++   
Sbjct: 13841 EFKERNSLLWKRANKTPIRMRDFKVTGLTEGLEYEFRVMAINLAGVGKPSLPSEPVVALD 13900

Query: 2078  -----GRKKTV-----QKTPFVTHPGYDTGN 2098
                  G+ + +       T   T P YD G+
Sbjct: 13901 PIDPPGKPEVINITRNSVTLIWTEPKYDGGH 13931



 Score = 72.8 bits (177), Expect = 4e-12
 Identities = 334/1588 (21%), Positives = 550/1588 (34%), Gaps = 285/1588 (17%)

Query: 828   VVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAV 883
             ++ WS P+    + ITG+ I+     +  +    +    +   ++ L  G +Y   + A 
Sbjct: 8842  LLNWSDPEDDGGSEITGF-IIERKDAKMHTWRQPIETERSKCDITGLLEGQEYKFRVIAK 8900

Query: 884   EENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPES----AVTGYRV 939
              +     PV I       P      SP  L + E T   +T+ W  P S     + GY +
Sbjct: 8901  NKFGCGPPVEIGPILAVDPLGPPT-SPERLTYTERTKSTITLDWKEPRSNGGSPIQGYII 8959

Query: 940   DVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLD- 998
             +    + P        +   T   V  L     Y F+V AV+   ES+P         D 
Sbjct: 8960  EKRRHDKPDFERVNKRLCPTTSFLVENLDEHQMYEFRVKAVNEIGESEPSLPLNVVIQDD 9019

Query: 999   --APTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPR-QYNVGPSVSKYPLRN 1055
                PT    ++    T+ V+   P        +   +T    P+ +++   +V + P   
Sbjct: 9020  EVPPTIKLRLSVRGDTIKVKAGEP------VHIPADVTGLPMPKIEWSKNETVIEKPTDA 9073

Query: 1056  LQPASEYTVSLVAIKGNQESPKAT----GVFTTLQP---GSSI------------PPYNT 1096
             LQ   E  VS    K     PKA     G +T       GS              PP N 
Sbjct: 9074  LQITKE-EVSRSEAKTELSIPKAVREDKGTYTVTASNRLGSVFRNVHVEVYDRPSPPRNL 9132

Query: 1097  EVTET---TIVITW-TPAPRIGFKLGVRPSQGGEAPR------EVTSDSGS--IVVSGLT 1144
              VT+    +  +TW  P    G ++        +A R      EVT+ +      +  L 
Sbjct: 9133  AVTDIKAESCYLTWDAPLDNGGSEITHYVIDKRDASRKKAEWEEVTNTAVEKRYGIWKLI 9192

Query: 1145  PGVEYVYTIQVLR-----DGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSW---- 1195
             P  +Y + ++ +      D  + D  ++        PP    + A    G + VSW    
Sbjct: 9193  PNGQYEFRVRAVNKYGISDECKSDKVVIQDPYRLPGPPGKPKVLARTK-GSMLVSWTPPL 9251

Query: 1196  ERSTTPDITGYRITTTPTNGQQGNSLEE--VVHADQSSCTFD--NLSPGLEYNVSVYTVK 1251
             +   +P ITGY +          + +    +         F+   L  G++Y      + 
Sbjct: 9252  DNGGSP-ITGYWLEKREEGSPYWSRVSRAPITKVGLKGVEFNVPRLLEGVKYQFRAMAIN 9310

Query: 1252  --------DDKESVPISDTIIPEVPQLTDLSFVDITDSSIGLRWTPL---NSSTIIGYRI 1300
                     +  +     D I P  P        D T SSI L W P      S I GY +
Sbjct: 9311  AAGIGPPSEPSDPEVAGDPIFPPGPPSCP-EVKDKTKSSISLGWKPPAKDGGSPIKGYIV 9369

Query: 1301  TVVAAG--EGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAV 1358
              +   G  +   + E     +     V  L+    Y   V  +   GES P+  T +   
Sbjct: 9370  EMQEEGTTDWKRVNEPDKLITTCECVVPNLKELRKYRFRVKAVNEAGESEPSDTTGEI-- 9427

Query: 1359  PPPTDLR-----FTNIGPDTMRVTWA-------------PPPS----IDLTNFLVRYSPV 1396
              P TD++     F +IG     V  A             P P      D          V
Sbjct: 9428  -PATDIQEEPEVFIDIGAQDCLVCKAGSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGV 9486

Query: 1397  KNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTP-LRGRQKTGLDSPTGI 1455
              +  + A+L  + + + +++           S+++  +  + T   R +       P  +
Sbjct: 9487  HDIPEDAQLETAENSSVIIIPECKRSHTGKYSITAKNKAGQKTANCRVKVMDVPGPPKDL 9546

Query: 1456  DFSDITANSFTVHWIAPRAT----ITGYRIRHHPEHFSGRPREDRVPH-SRNSITLTNLT 1510
               SDIT  S  + W  P       I GY I        G+      P     +  + +L 
Sbjct: 9547  KVSDITRGSCRLSWKMPDDDGGDRIKGYVIEKRT--IDGKAWTKVNPDCGSTTFVVPDLL 9604

Query: 1511  PGTEYVVSIVALNGREESPLLIGQQSTVS-------DVPRDLEVVAATPTSLLISWDAPA 1563
                +Y   + A N     P +   Q T +       D P  L++   T  ++ +SW  P 
Sbjct: 9605  SEQQYFFRVRAENRFGIGPPVETIQRTTARDPIYPPDPPIKLKIGLITKNTVHLSWKPP- 9663

Query: 1564  VTVRYYRITYGETGGNSPVQEFTVP-------GSKSTA--------------TISGLKPG 1602
                        +  G SPV  + V        G+K  A              T+  L  G
Sbjct: 9664  -----------KNDGGSPVTHYIVECLAWDPTGTKKEAWRQCNKRDVEELQFTVEDLVEG 9712

Query: 1603  VDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTG 1662
              +Y   V AV   G S  S+             P   Q  D+   SI +K        T 
Sbjct: 9713  GEYEFRVKAVNAAGVSKPSATV----------GPCDCQRPDMPP-SIDLKEFMEVEEGTN 9761

Query: 1663  YRVTTTPKNGPGPT----KTKTAGPDQTEMTIEGLQPTVEYV----VSVYAQNPSGESQP 1714
               +    K  P PT    K     PD  E  +         V      V  Q+   ++  
Sbjct: 9762  VNIVAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDTGL 9821

Query: 1715  LVQTAVTNIDR---------------PKG-LAFTDVDVDSIKIAWESPQ----GQVSRYR 1754
                TAV N+                 P G + F  V  D + ++W  P+     +++ Y 
Sbjct: 9822  YTITAVNNLGTASKEMRLNVLGRPGPPVGPIKFESVSADQMTLSWFPPKDDGGSKITNYV 9881

Query: 1755  VTY--SSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVA-----LHDDMESQPLIG 1807
             +    ++ +  +H    + + +E T  +  L  G EY   ++A     + + ++S+P   
Sbjct: 9882  IEKREANRKTWVHV---SSEPKECTYTIPKLLEGHEYVFRIMAQNKYGIGEPLDSEPETA 9938

Query: 1808  TQSTAIP-APTDLKFTQVTPTSLSAQWTPPNVQ----LTGYRVRVTPKEKTGPM-KEINL 1861
                 ++P AP     + VT  S++  W  P       +TGY + +  K+ T    K +N 
Sbjct: 9939  RNLFSVPGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPVTGYWLEM--KDTTSKRWKRVNR 9996

Query: 1862  APDSS-----SVVVSGLMVATKYEVSVYALKD------TLTSRPAQGVVTTLENVSPPRR 1910
              P  +     S  V+GL+  + Y+  VYA+        +L S PA    T  + ++PP  
Sbjct: 9997  DPIKAMTLGVSYKVTGLIEGSDYQFRVYAINAAGVGPASLPSDPA----TARDPIAPPGP 10052

Query: 1911  A--RVTDATETTITISWRTKTET----ITGFQVDAVPANGQTPIQRTIKPDVRS--YTIT 1962
                +VTD T+++  + W    +     +TG+ V+     G+   ++    +VR     +T
Sbjct: 10053 PFPKVTDWTKSSADLEWSPPLKDGGSKVTGYIVE-YKEEGKEEWEKGKDKEVRGTKLVVT 10111

Query: 1963  GLQPGTDYKIYLYTLNDNARSSPV----VIDASTAIDAPSNLRFLATTPNSLLVSWQPPR 2018
             GL+ G  YK  +  +N      P     VI+    + +P +L+  A+  + ++V      
Sbjct: 10112 GLKEGAFYKFRVRAVNIAGIGEPGEVTDVIEMKDRLVSP-DLQLDASVRDRIVVH-AGGV 10169

Query: 2019  ARITGYIIKYEKPGSPPREVV--PRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPL 2076
              RI  Y+      G PP  V      R    EATI      T      + +KN Q+S   
Sbjct: 10170 IRIIAYV-----SGKPPPTVTWNMNERTLPQEATIE-----TTAISSSMVIKNCQRSHQG 10219

Query: 2077  I----------GRKKTV----------QKTPFVTHPGYDTGNGIQL----PGTSGQQPSV 2112
             +           RKKT+            TPF+ H    T    +L    P   G  P +
Sbjct: 10220 VYSLLAKNEAGERKKTIIVDVLDVPGPVGTPFLAHNL--TNESCKLTWFSPEDDGGSP-I 10276

Query: 2113  GQQMIFEEHGFRRTTPPTTATPIRHRPRPYPPNVGQ----EALSQTTISWAPFQDTSEYI 2168
                +I +    RR   P T T  R          G+       ++ +I   PF +TSE +
Sbjct: 10277 TNYVIEKRESDRRAWTPVTYTVTRQNATVQGLIQGKAYFFRIAAENSIGMGPFVETSEAL 10336

Query: 2169  ISCHPVGTDEEPLQFRVPG-TSTSATLT 2195
             +   P+   E P    V   T  + TLT
Sbjct: 10337 VIREPITVPERPEDLEVKEVTKNTVTLT 10364



 Score = 72.0 bits (175), Expect = 7e-12
 Identities = 342/1612 (21%), Positives = 545/1612 (33%), Gaps = 290/1612 (17%)

Query: 628   IQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISI 684
             + W +P+    S I+ Y++  R  +    W   T      + T++GL  G  Y  ++ + 
Sbjct: 10263 LTWFSPEDDGGSPITNYVIEKRESDRRA-WTPVTYTVTRQNATVQGLIQGKAYFFRIAAE 10321

Query: 685   QQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSAS 744
                G        F  TS +  +        T P  P       V E+T ++  ++W    
Sbjct: 10322 NSIGMGP-----FVETSEALVIREPI----TVPERP---EDLEVKEVTKNTVTLTWNPPK 10369

Query: 745   DTVSGFRVEYELSEE--GDEPQYLDLPSTATS--VNIPDLLPGRKYIVNVYQISEDGEQS 800
                    + Y L     G E  +        S    +  L  G  Y   V  ++  G+  
Sbjct: 10370 YDGGSEIINYVLESRLIGTEKFHKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGK 10429

Query: 801   LILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPE 860
                 T   T  D    PT+       + +R     A    Y     P V     E ++ E
Sbjct: 10430 PSFCTKPITCKDELAPPTLHLDFRDKLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLE 10489

Query: 861   TANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQET---TGTPRSDTVPSPRD----L 913
               +  T     P       I A   +     VV++  T    G  + + V  P      +
Sbjct: 10490 --DDRTHIKTTPATLALEKIKAKRSDSGKYCVVVENSTGSRKGFCQVNVVDRPGPPVGPV 10547

Query: 914   QFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPGEHGQRLPI---SRNTFAEVTG 966
              F EVT   + I W PP     S +T Y ++   V         +P+   S  T  +V+ 
Sbjct: 10548 SFDEVTKDYMVISWKPPLDDGGSKITNYIIEKKEVG----KDVWMPVTSASAKTTCKVSK 10603

Query: 967   LSPGVTYYFKVFAVSHGRESKPLTAQQTTKLD------APTNLQFVNETDSTVLVRWTPP 1020
             L  G  Y F++ A +    S PL +      D      AP        T  + LV W  P
Sbjct: 10604 LLEGKDYIFRIHAENLYGISDPLVSDSMKAKDRFRVPDAPDQPIVTEVTKDSALVTWNKP 10663

Query: 1021  R---AQITGYRLTVGLTRRGQPRQYNVGP--SVSKYPLRNLQPASEYTVSLVA---IKGN 1072
                   IT Y L    T   +  +    P    +K+ + +L    +Y   + A   I   
Sbjct: 10664 HDGGKPITNYILEKRETMSKRWARVTKDPIHPYTKFRVPDLLEGCQYEFRVSAENEIGIG 10723

Query: 1073  QESPKATGVFTTLQPGSSIPPYNTEVTETT---IVITWTPAPRIGFKLGVRPSQGGEAPR 1129
               SP +  VF         PP N E  +TT   + +TW P                  PR
Sbjct: 10724 DPSPPSKPVFAKDPIAKPSPPVNPEAIDTTCNSVDLTWQP------------------PR 10765

Query: 1130  EVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTG 1189
                 D GS ++        Y+   Q + D + R A              N   E+ P+T 
Sbjct: 10766 H---DGGSKILG-------YIVEYQKVGDEEWRRA--------------NHTPESCPETK 10801

Query: 1190  VLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPG---LEYNVS 1246
                       T     +R+      G+      +  H  +     D L P    L+ N++
Sbjct: 10802 YKVTGLRDGQTYK---FRVLAVNAAGES-----DPAHVPEPVLVKDRLEPPELILDANMA 10853

Query: 1247  VYTVKDDKESVPISDT-----IIPEVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGYRIT 1301
                    ++ + + DT     II  VP      F  +T       W   +       RI 
Sbjct: 10854 ------REQHIKVGDTLRLSAIIKGVP------FPKVT-------WKKEDRDAPTKARID 10894

Query: 1302  VVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAVPPP 1361
             V   G  + I  +      G Y++T   P     +SV  L+                 PP
Sbjct: 10895 VTPVGSKLEI-RNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDKPG------------PP 10941

Query: 1362  TDLRFTNIGPDTMRVTWAPPPSID---LTNFLVRYSPVKNEEDVAELSISPSDNAVVLTN 1418
              DL  + I  D+  +TW  P       +TN++V    V + +  + LS +    +    +
Sbjct: 10942 RDLEVSEIRKDSCYLTWKEPLDDGGSVITNYVVERRDVASAQ-WSPLSATSKKKSHFAKH 11000

Query: 1419  LLPGTEYVVSVSSVYEQHESTPLRGRQKT--GLDS------PTGIDFSDITANSFTVHWI 1470
             L  G +Y+  V++   Q+   P     K    LD       P  +   D+     ++ W 
Sbjct: 11001 LNEGNQYLFRVAAE-NQYGRGPFVETPKPIKALDPLHPPGPPKDLHHVDVDKTEVSLVWN 11059

Query: 1471  APR----ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN--- 1523
              P     + ITGY + +  E      +   V +      +T L  G  Y   + A N   
Sbjct: 11060 KPDRDGGSPITGYLVEYQEEGTQDWIKFKTVTNLE--CVVTGLQQGKTYRFRVKAENIVG 11117

Query: 1524  -GREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPV 1582
              G  ++ + I  Q  +  VP  +E+       L++       TVR+  I  G      P 
Sbjct: 11118 LGLPDTTIPIECQEKL--VPPSVELDVKLIEGLVVK---AGTTVRFPAIIRGVP---VPT 11169

Query: 1583  QEFTVPGSK---------------STATISGL--KPGVDYTITVYAVTGRGDSPASSKPI 1625
              ++T  GS+               S  TI     +   +Y ITV        + A SK +
Sbjct: 11170 AKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEYQITV-------SNAAGSKTV 11222

Query: 1626  SINYRTEIDKPSQ----MQVTDVQDNSISVKWLP----SSSPVTGYRVTT--TPKNGPGP 1675
             +++  T +D P      + + DV    +++ W P      SPV  Y V    T K+  G 
Sbjct: 11223 AVHL-TVLDVPGPPTGPINILDVTPEHMTISWQPPKDDGGSPVINYIVEKQDTRKDTWGV 11281

Query: 1676  TKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDR------PKGL 1729
                 ++G  +T++ I  LQ   EYV  V A+N  G   PL  T      +      P   
Sbjct: 11282 V---SSGSSKTKLKIPHLQKGCEYVFRVRAENKIGVGPPLDSTPTVAKHKFSPPSPPGKP 11338

Query: 1730  AFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQ----GLRP 1785
               TD+  ++  ++W  P+         Y      +   +   + +   A+L+    GL  
Sbjct: 11339 VVTDITENAATVSWTLPKSDGGSPITGYYMERREVTGKWVRVN-KTPIADLKFRVTGLYE 11397

Query: 1786  GSEYTVSVVALH------DDMESQPLIGTQSTAIPA-PTDLKFTQVTPTSLSAQWTPP-- 1836
             G+ Y   V A +          S P+   +    P  P + K    +  +    WT P  
Sbjct: 11398 GNTYEFRVFAENLAGLSKPSPSSDPIKACRPIKPPGPPINPKLKDKSRETADLVWTKPLS 11457

Query: 1837  --NVQLTGYRVRVTPKEKTGPMKEINLAP--DSSSVVVSGLMVATKYEVSVYALKDTLTS 1892
                  + GY V    K  T     IN        +  V GL+   +Y   + A       
Sbjct: 11458 DGGSPILGYVVE-CQKPGTAQWNRINKDELIRQCAFRVPGLIEGNEYRFRIKAANIVGEG 11516

Query: 1893  RP---AQGVVTTLENVSPPR-------RARVTDATETTITISWRTK-------TETITG- 1934
              P   A+ V+   + + PP        R  +T     TI I  R K       T T  G 
Sbjct: 11517 EPRELAESVIAK-DILHPPEVELDVTCRDVITVRVGQTIRILARVKGRPEPDITWTKEGK 11575

Query: 1935  -----FQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVID 1989
                   +VD +    +  +Q  IK  VR+           Y I     + +A+ S +V  
Sbjct: 11576 VLVREKRVDLIQDLPRVELQ--IKEAVRA-------DHGKYIISAKNSSGHAQGSAIV-- 11624

Query: 1990  ASTAIDAP---SNLRFLATTPNSLLVSWQPP----RARITGYIIKYEKPGSPPREVVPRP 2042
                 +D P    NL+    T  +  +SW+ P     + IT +I++Y KP      +V   
Sbjct: 11625 --NVLDRPGPCQNLKVTNVTKENCTISWENPLDNGGSEITNFIVEYRKPNQKGWSIV--- 11679

Query: 2043  RPGVTEATI-TGLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQKTPFVTHPG 2093
                VT+  I   L    EY   V A +N     P I  K  +     +  PG
Sbjct: 11680 ASDVTKRLIKANLLANNEYYFRVCA-ENKVGVGPTIETKTPILAINPIDRPG 11730



 Score = 64.3 bits (155), Expect = 1e-09
 Identities = 115/519 (22%), Positives = 183/519 (35%), Gaps = 81/519 (15%)

Query: 1633  IDKPS---QMQVTDVQDNSISVKWLPSSSP----VTGYRVTTTP-KNGPGPTKTKTAGPD 1684
             +DKP     +++ DV  +  +V W P        +  Y +     K     T + T    
Sbjct: 11922 LDKPGPVRNLKIVDVSSDRCTVCWDPPEDDGGCEIQNYILEKCETKRMVWSTYSATVLTP 11981

Query: 1685  QTEMT--IEGLQPTVEYVVSVYAQN-----PSGESQPLV-QTAVTNIDRPKGLAFTDVDV 1736
              T +T  IEG     EY+  V A+N     P  ES+P++ +T      RP     T V  
Sbjct: 11982 GTTVTRLIEGN----EYIFRVRAENKIGTGPPTESKPVIAKTKYDKPGRPDPPEVTKVSK 12037

Query: 1737  DSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGE----EDTAELQGLRPGSEYTVS 1792
             + + + W  P+    +    Y   +   H     P  +    E   ++Q L P  EY   
Sbjct: 12038 EEMTVVWNPPEYDGGKSITGYFLEKKEKHSTRWVPVNKSAIPERRMKVQNLLPDHEYQFR 12097

Query: 1793  VVALHD------DMESQPLIGTQSTAIPAP-TDLKFTQVTPTSLSAQWTPP----NVQLT 1841
             V A ++       + S+P++       P P T+ +    T  S++  W  P       + 
Sbjct: 12098 VKAENEIGIGEPSLPSRPVVAKDPIEPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAPII 12157

Query: 1842  GYRVRVTPKEKTGP----MKEINLAPD--SSSVVVSGLMVATKYEVSVYALKDTLTSRPA 1895
             GY V + PK          K  N A         V+ L    +YE  V A       RPA
Sbjct: 12158 GYVVEMRPKIADASPDEGWKRCNAAAQLVRKEFTVTSLDENQEYEFRVCAQNQVGIGRPA 12217

Query: 1896  Q--GVVTTLENVSPPRRARVTDATETTIT-------------------ISWRTK--TETI 1932
             +    +   E + PP         +  I                    ++WR       +
Sbjct: 12218 ELKEAIKPKEILEPPEIDLDASMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVV 12277

Query: 1933  TGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDAST 1992
                QVD V       I  + + D   Y++T + P  +  +++     N R    V+D   
Sbjct: 12278 RKGQVDLVDTMAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFV-----NVR----VLDTPG 12328

Query: 1993  AIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREVVPRPRPGVTE 2048
              +   S+L+    T  S  VSW PP     +++T YI++  +        V  P    T 
Sbjct: 12329 PV---SDLKVSDVTKTSCHVSWAPPENDGGSQVTHYIVEKREADRKTWSTVT-PEVKKTS 12384

Query: 2049  ATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQKTP 2087
               +T L PG EY   V A+       P    K  +   P
Sbjct: 12385 FHVTNLVPGNEYYFRVTAVNEYGPGVPTDVPKPVLASDP 12423



 Score = 61.6 bits (148), Expect = 9e-09
 Identities = 181/841 (21%), Positives = 296/841 (35%), Gaps = 156/841 (18%)

Query: 1360 PPTDLRFTNIGPDTMRVTWAPPPS---IDLTNFLVRYSPVKNEEDVAELSISPSDNAVVL 1416
            P  +L  T      + + W  P +     +  ++V    +K +  V     + S    V 
Sbjct: 6720 PVRNLEVTETFDGEVSLAWEEPLTDGGSKIIGYVVERRDIKRKTWVLATDRAESCEFTVT 6779

Query: 1417 TNLLPGTEYVVSVSS-----VYEQHES-TPLRGRQKTGLDSPT-GIDFSDITANSFTVHW 1469
                 G EY+  VS+       E  E+  P+  R K  +  P   +  +D+     ++ W
Sbjct: 6780 GLQKGGVEYLFRVSARNRVGTGEPVETDNPVEARSKYDVPGPPLNVTITDVNRFGVSLTW 6839

Query: 1470 IAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGR 1525
              P     A IT Y I    +          V     S T+T++  G EY   +     R
Sbjct: 6840 EPPEYDGGAEITNYVIELRDKTSIRWDTAMTVRAEDLSATVTDVVEGQEYSFRV-----R 6894

Query: 1526 EESPLLIGQQSTVSDV------------PRDLEVVAATPTSLLISWDAP----AVTVRYY 1569
             ++ + +G+ S  +              P +L     T +S+ + W+ P       +  Y
Sbjct: 6895 AQNRIGVGKPSAATPFVKVADPIERPSPPVNLTSSDQTQSSVQLKWEPPLKDGGSPILGY 6954

Query: 1570 RITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINY 1629
             I   E G ++ ++       + T  ++GL+ G  Y   V A    G S  S     +  
Sbjct: 6955 IIERCEEGKDNWIRCNMKLVPELTYKVTGLEKGNKYLYRVSAENKAGVSDPSEILGPLTA 7014

Query: 1630 RTEIDKPSQMQVTDVQDNSISVKWLPSSS--PVTGYRVTTTPKNGPGPTKTKTAGPDQTE 1687
                 +P+ M ++  +D    +   P +   P TGY         P PT T   G    E
Sbjct: 7015 DDAFVEPT-MDLSAFKDGLEVIVPNPITILVPSTGY---------PRPTATWCFGDKVLE 7064

Query: 1688 ----MTIEGLQPTVEYVVSVYAQNPSG----ESQPLVQTAVTNID--------RPKGLAF 1731
                + ++ L    E V+S   ++  G    + +  V+T    ID         PK L F
Sbjct: 7065 TGDRVKMKTLSAYAELVISPSERSDKGIYTLKLENRVKTISGEIDVNVIARPSAPKELKF 7124

Query: 1732 TDVDVDSIKIAWESPQ----GQVSRY--------RVTYSSPEDGIHEL-FPAPDGEEDTA 1778
             D+  DS+ + WE P       ++ Y        R T++   D + +L F  PD      
Sbjct: 7125 GDITKDSVHLTWEPPDDDGGSPLTGYVVEKREVSRKTWTKVMDFVTDLEFTVPD------ 7178

Query: 1779 ELQGLRPGSEYTVSVVALHDDMESQPL-------IGTQSTAIPAPTDLKFTQVTPTSLSA 1831
                L  G EY   V A +     +P        + T +T    P ++K+   T  S+  
Sbjct: 7179 ----LVQGKEYLFKVCARNKCGPGEPAYVDEPVNMSTPATVPDPPENVKWRDRTANSIFL 7234

Query: 1832 QWTPP----NVQLTGYRVRVTPKEKTGPMKEINLAPD--SSSVVVSGLMVATKYEVSVYA 1885
             W PP      ++ GY V   P+   G  K +        + + V+GL     Y   V A
Sbjct: 7235 TWDPPKNDGGSRIKGYIVERCPR---GSDKWVACGEPVAETKMEVTGLEEGKWYAYRVKA 7291

Query: 1886 LKDTLTSRPAQGVVTTLENVSPPRRARVTDATETT-----------ITISWRTKTE---T 1931
            L     S+P++          P    +  D  E             +T+   TK E   T
Sbjct: 7292 LNRQGASKPSR----------PTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPAT 7341

Query: 1932 ITGFQVDAVPANGQTPIQRTIKPDVR----------SYTITGLQPGTDYKIYLYTLNDNA 1981
            +TG      P    T     +K D R          + TI   +        +  +N   
Sbjct: 7342 VTG---KPEPKITWTKADMILKQDKRITIENVPKKSTVTIVDSKRSDTGTYIIEAVNVCG 7398

Query: 1982 RSSPVV-IDASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPR 2036
            R++ VV ++       P+       T  S L++W PPR    ++IT Y+++     S   
Sbjct: 7399 RATAVVEVNVLDKPGPPAAFDITDVTNESCLLTWNPPRDDGGSKITNYVVERRATDS--- 7455

Query: 2037 EVVPRPRPGV--TEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQKTPFVTHPGY 2094
            EV  +    V  T    T L P  EY   V A       E + G  + VQ +P      +
Sbjct: 7456 EVWHKLSSTVKDTNFKATKLIPNKEYIFRVAA-------ENMYGVGEPVQASPITAKYQF 7508

Query: 2095 D 2095
            D
Sbjct: 7509 D 7509



 Score = 58.2 bits (139), Expect = 1e-07
 Identities = 314/1663 (18%), Positives = 573/1663 (34%), Gaps = 254/1663 (15%)

Query: 611   PVEVFITETPSQP-----------NSHPIQWNAPQPS---HISKYILRWRPKNSVGRWKE 656
             P+ V     PS+P           +S  + W+ P+ +    I+ Y +  R + S   WK 
Sbjct: 21276 PITVITLGPPSKPKGPIRFDEIKADSVILSWDVPEDNGGGEITCYSIEKR-ETSQTNWKM 21334

Query: 657   ATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETT 716
                     ++ +  L     Y+ ++ +  +YG              S P+ S+ +  +  
Sbjct: 21335 VCSSVARTTFKVPNLVKDAEYQFRVRAENRYG-------------VSQPLVSSIIVAKHQ 21381

Query: 717   PFSPLVATSESVTEITASSFVVSW----VSASDTVSGFRVEYELSEEGDEPQYLDLPSTA 772
                P       +  +T+    ++W          V+GF VE +        +    P + 
Sbjct: 21382 FRIPGPPGKPVIYNVTSDGMSLTWDAPVYDGGSEVTGFHVEKKERNSILWQKVNTSPISG 21441

Query: 773   TSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDP--TVDQVDDT--SIV 828
                    L+ G  Y   VY  +  G  S     S+ T   +P DP  T D +D T  +I 
Sbjct: 21442 REYRATGLVEGLDYQFRVYAENSAGLSSPS-DPSKFTLAVSPVDPPGTPDYIDVTRETIT 21500

Query: 829   VRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETAN-SVTLSDLQPGVQYNITIYA- 882
             ++W+ P     + I GY I      E      N  + +    T++ L PG +Y   I A 
Sbjct: 21501 LKWNPPLRDGGSKIVGYSIEKRQGNE-RWVRCNFTDVSECQYTVTGLSPGDRYEFRIIAR 21559

Query: 883   -----VEENQESTPVVIQQETTGTPRSDTVPSPRD---LQFVEVTDVKVTIMWTPPESAV 934
                  +    +S+ +++ ++    P  +  P   D   ++  E   +K  +   P    V
Sbjct: 21560 NAVGTISPPSQSSGIIMTRDENVPPIVEFGPEYFDGLIIKSGESLRIKALVQGRPVPR-V 21618

Query: 935   TGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFK--------VFAVSHGRES 986
             T ++  V              I +    E+T +    + + +        V+ V     S
Sbjct: 21619 TWFKDGV-------------EIEKRMNMEITDVLGSTSLFVRDATRDHRGVYTVEAKNAS 21665

Query: 987   KPLTAQQTTKL-DAPTN----LQFVNETDSTVLVRWTPPR----AQITGYRLTVGLTRRG 1037
                 A+   K+ D P      ++F N T   + + W  P     A IT Y +    T R 
Sbjct: 21666 GSAKAEIKVKVQDTPGKVVGPIRFTNITGEKMTLWWDAPLNDGCAPITHYIIEKRETSRL 21725

Query: 1038  QPRQYNVGPSVSKYPLRNLQPASEYTVSLVAI------KGNQESPKATGVFTTLQPGSSI 1091
                          Y    L   +EY   + A+      +     P    +  T+     I
Sbjct: 21726 AWALIEDKCEAQSYTAIKLINGNEYQFRVSAVNKFGVGRPLDSDPVVAQIQYTVPDAPGI 21785

Query: 1092  PPYNTEVTETTIVITWTPAPRIG------FKLGVRPSQGGEAPREVTSDSGS---IVVSG 1142
             P   + +T  +I +TW      G      + L  R  +     + ++    S     V+G
Sbjct: 21786 PE-PSNITGNSITLTWARPESDGGSEIQQYILERREKKSTRWVKVISKRPISETRFKVTG 21844

Query: 1143  LTPGVEYVYTIQVLRDGQERDAPIVNKVVT---PLSPPTNLHLEANPDTGVLTVSWERST 1199
             LT G EY + +          A  +++++    P++PP    +    DT   TVS E S 
Sbjct: 21845 LTEGNEYEFHVMAENAAGVGPASGISRLIKCREPVNPPGPPTVVKVTDTSKTTVSLEWSK 21904

Query: 1200  TP-----DITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKD-- 1252
                    +I GY I     +    + +       ++  T  +L  G EY   V  +    
Sbjct: 21905 PVFDGGMEIIGYIIEMCKADLGDWHKVNAEACV-KTRYTVTDLQAGEEYKFRVSAINGAG 21963

Query: 1253  DKESVPISDTI-------IPEVPQLTDLSFVDITDSSIGLR--------------WTPLN 1291
               +S  ++ TI        PE+    +     +  +   +R              W+  +
Sbjct: 21964 KGDSCEVTGTIKAVDRLTAPELDIDANFKQTHVVRAGASIRLFIAYQGRPTPTAVWSKPD 22023

Query: 1292  SSTIIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTT 1351
             S+  +   I    +   + + E+   +  G YT+T            +   +G +S   T
Sbjct: 22024 SNLSLRADIHTTDSFSTLTV-ENCNRNDAGKYTLT------------VENNSGSKSITFT 22070

Query: 1352  LTQQTAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAE---LSIS 1408
             +       PP  + F ++   +  + W   P +D    +  Y   K E        +S  
Sbjct: 22071 VKVLDTPGPPGPITFKDVTRGSATLMW-DAPLLDGGARIHHYVVEKREASRRSWQVISEK 22129

Query: 1409  PSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDS----PTGIDFSDITANS 1464
              +     + +L  G  Y   VS+V E     P    +          P  +D  D + +S
Sbjct: 22130 CTRQIFKVNDLAEGVPYYFRVSAVNEYGVGEPYEMPEPIVATEQPAPPRRLDVVDTSKSS 22189

Query: 1465  FTVHWIAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRN-SITLTNLTPGTEYVVSI 1519
               + W+ P     + ITGY +    +   G        H++  + T+  L   TEY   +
Sbjct: 22190 AVLAWLKPDHDGGSRITGYLLEMRQK---GSDFWVEAGHTKQLTFTVERLVEKTEYEFRV 22246

Query: 1520  VALNGREESPLLIGQQSTVSDVPR-----DLEVV--------AATPTSL---LISWDAPA 1563
              A N    S       S +   P+     DL  +        A +P ++   +    AP 
Sbjct: 22247 KAKNDAGYSEPREAFSSVIIKEPQIEPTADLTGITNQLITCKAGSPFTIDVPISGRPAPK 22306

Query: 1564  VTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVD--YTITVYAVTGRGDSPAS 1621
             VT +   +   ET   S     T    ++T T+     G    Y +T+       ++ A 
Sbjct: 22307 VTWKLEEMRLKETDRVS----ITTTKDRTTLTVKDSMRGDSGRYFLTL-------ENTAG 22355

Query: 1622  SKPISINYRTEIDKPSQM----QVTDVQDNSISVKWLP----SSSPVTGYRVTTTPKNGP 1673
              K  S+     I +P  +    +V+ V   S  + W        + +T Y +    ++G 
Sbjct: 22356 VKTFSVTV-VVIGRPGPVTGPIEVSSVSAESCVLSWGEPKDGGGTEITNY-IVEKRESGT 22413

Query: 1674  GPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAV------TNIDRPK 1727
                +   +   +T++ +  L   +EY   V ++N  G S+PL    +           P 
Sbjct: 22414 TAWQLVNSSVKRTQIKVTHLTKYMEYSFRVSSENRFGVSKPLESAPIIAEHPFVPPSAPT 22473

Query: 1728  GLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGE----EDTAELQGL 1783
                   V  +++ I WE P        + Y   +   + +    + +    E   ++ GL
Sbjct: 22474 RPEVYHVSANAMSIRWEEPYHDGGSKIIGYWVEKKERNTILWVKENKVPCLECNYKVTGL 22533

Query: 1784  RPGSEYTVSVVALH------DDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPP- 1836
               G EY     AL+          S+P++      + AP   + T VT +++S  W+ P 
Sbjct: 22534 VEGLEYQFRTYALNAAGVSKASEASRPIMA--QNPVDAPGRPEVTDVTRSTVSLIWSAPA 22591

Query: 1837  ---NVQLTGYRVRVTPKEKTGP---MKEINLAPDSSSVVVSGLMVATKYEVSVYALKDT- 1889
                  ++ GY +   P  + G    +K        +   V+ L     YE  V A     
Sbjct: 22592 YDGGSKVVGYIIERKPVSEVGDGRWLKCNYTIVSDNFFTVTALSEGDTYEFRVLAKNAAG 22651

Query: 1890  LTSRPAQ--GVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVP------ 1941
             + S+ ++  G VT  +  +PP+     DA      ++ R  ++ +    V   P      
Sbjct: 22652 VISKGSESTGPVTCRDEYAPPKAE--LDARLHGDLVTIRAGSDLVLDAAVGGKPEPKIIW 22709

Query: 1942  ANGQTPIQRTIKPDV-----RSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDA 1996
               G   +    K  +     R+  +      +D   Y  T+  NA  +  V      +D+
Sbjct: 22710 TKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSGKYTLTVK-NASGTKAVSVMVKVLDS 22768

Query: 1997  P---SNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREVVPRPRPGVTEA 2049
             P     L     T     ++W  P+    A IT YI++  +       +V    P ++  
Sbjct: 22769 PGPCGKLTVSRVTQEKCTLAWSLPQEDGGAEITHYIVERRETSRLNWVIVEGECPTLS-Y 22827

Query: 2050  TITGLEPGTEYTIYVIALKN-----NQKSEPLIGRKKTVQKTP 2087
              +T L    EY   V A+         +SEP++ R      +P
Sbjct: 22828 VVTRLIKNNEYIFRVRAVNKYGPGVPVESEPIVARNSFTIPSP 22870



 Score = 55.5 bits (132), Expect = 6e-07
 Identities = 128/535 (23%), Positives = 202/535 (37%), Gaps = 90/535 (16%)

Query: 593   GIGEWHCQPLQTYPSSSGPVEVFITETPSQP-------NSHPIQWNAPQ---PSHISKYI 642
             GIGE    PL + P ++  +   +   P +P       NS  + W  P+    S ++ Y 
Sbjct: 9926  GIGE----PLDSEPETARNL-FSVPGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPVTGYW 9980

Query: 643   LRWRPKNSVGRWK-------EATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRF 695
             L  +   S  RWK       +A   G   SY + GL  G  Y+ ++ +I   G    +  
Sbjct: 9981  LEMKDTTSK-RWKRVNRDPIKAMTLGV--SYKVTGLIEGSDYQFRVYAINAAGVGPASL- 10036

Query: 696   DFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWV----SASDTVSGFR 751
                    S P T+        P +P       VT+ T SS  + W          V+G+ 
Sbjct: 10037 ------PSDPATARD------PIAPPGPPFPKVTDWTKSSADLEWSPPLKDGGSKVTGYI 10084

Query: 752   VEYELSEEGDEP--QYLDLPSTATSVNIPDLLPGRKY-----IVNVYQISEDGEQSLILS 804
             VEY+  EEG E   +  D     T + +  L  G  Y      VN+  I E GE + ++ 
Sbjct: 10085 VEYK--EEGKEEWEKGKDKEVRGTKLVVTGLKEGAFYKFRVRAVNIAGIGEPGEVTDVIE 10142

Query: 805   TSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETA-- 862
                       PD  +D      IVV        I        P+V  +  E  LP+ A  
Sbjct: 10143 MKDRLVS---PDLQLDASVRDRIVVHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEATI 10199

Query: 863   ------NSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFV 916
                   +S+ + + Q   Q   ++ A  E  E    +I            VP P    F+
Sbjct: 10200 ETTAISSSMVIKNCQRSHQGVYSLLAKNEAGERKKTIIVDVLD-------VPGPVGTPFL 10252

Query: 917   --EVTDVKVTIMWTPPE----SAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPG 970
                +T+    + W  PE    S +T Y ++    +          ++R   A V GL  G
Sbjct: 10253 AHNLTNESCKLTWFSPEDDGGSPITNYVIEKRESDRRAWTPVTYTVTRQN-ATVQGLIQG 10311

Query: 971   VTYYFKVFA---VSHG---RESKPLTAQQT-TKLDAPTNLQFVNETDSTVLVRWTPPR-- 1021
               Y+F++ A   +  G     S+ L  ++  T  + P +L+    T +TV + W PP+  
Sbjct: 10312 KAYFFRIAAENSIGMGPFVETSEALVIREPITVPERPEDLEVKEVTKNTVTLTWNPPKYD 10371

Query: 1022  --AQITGYRLTVGLTRRGQPRQYNVGPSVS-KYPLRNLQPAS--EYTVSLVAIKG 1071
               ++I  Y L   L    +  +      +S KY ++ L+     EY VS V I G
Sbjct: 10372 GGSEIINYVLESRLIGTEKFHKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVG 10426



 Score = 52.8 bits (125), Expect = 4e-06
 Identities = 80/336 (23%), Positives = 120/336 (35%), Gaps = 46/336 (13%)

Query: 602  LQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQP---SHISKYILRWRPKN-SVGRWKEA 657
            ++ Y   S P  + +T+  ++  S  + W+AP     S I+ Y++  R  +     W+E 
Sbjct: 9120 VEVYDRPSPPRNLAVTDIKAE--SCYLTWDAPLDNGGSEITHYVIDKRDASRKKAEWEEV 9177

Query: 658  TIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTP 717
            T       Y I  L P   YE ++ ++ +YG  +  + D         V  +       P
Sbjct: 9178 TNTAVEKRYGIWKLIPNGQYEFRVRAVNKYGISDECKSD-------KVVIQDPYRLPGPP 9230

Query: 718  FSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTA----- 772
              P V         T  S +VSW    D        Y L +  +   Y    S A     
Sbjct: 9231 GKPKVLAR------TKGSMLVSWTPPLDNGGSPITGYWLEKREEGSPYWSRVSRAPITKV 9284

Query: 773  ----TSVNIPDLLPGRKY-----IVNVYQISEDGEQSLILSTSQTTAPDAPPD-PTVDQV 822
                   N+P LL G KY      +N   I    E S          P  PP  P V   
Sbjct: 9285 GLKGVEFNVPRLLEGVKYQFRAMAINAAGIGPPSEPSDPEVAGDPIFPPGPPSCPEVKDK 9344

Query: 823  DDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPE---TANSVTLSDLQPGVQ 875
              +SI + W  P     +PI GY +            +N P+   T     + +L+   +
Sbjct: 9345 TKSSISLGWKPPAKDGGSPIKGYIVEMQEEGTTDWKRVNEPDKLITTCECVVPNLKELRK 9404

Query: 876  YNITIYAVEENQESTPVVIQQETTG-TPRSDTVPSP 910
            Y   + AV E  ES P     +TTG  P +D    P
Sbjct: 9405 YRFRVKAVNEAGESEP----SDTTGEIPATDIQEEP 9436



 Score = 48.5 bits (114), Expect = 8e-05
 Identities = 107/537 (19%), Positives = 187/537 (34%), Gaps = 65/537 (12%)

Query: 610   GPVEVFITETPSQPNSHPIQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSY 666
             GPV        ++ + H + W  P+    S ++ YI+  R  +    W   T      S+
Sbjct: 12328 GPVSDLKVSDVTKTSCH-VSWAPPENDGGSQVTHYIVEKREADRK-TWSTVTPEVKKTSF 12385

Query: 667   TIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSE 726
              +  L PG  Y  ++ ++ +YG           T    PV ++    E  P   L     
Sbjct: 12386 HVTNLVPGNEYYFRVTAVNEYG-------PGVPTDVPKPVLASDPLSEPDPPRKL----- 12433

Query: 727   SVTEITASSFVVSWV----SASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLP 782
              VTE+T +S  ++W+         + G+   Y   E+  +           S+ +  L  
Sbjct: 12434 EVTEMTKNSATLAWLPPLRDGGAKIDGYITSYREEEQPADRWTEYSVVKDLSLVVTGLKE 12493

Query: 783   GRKY-----IVNVYQISEDGEQSLILSTSQTTAPD---APPDPTVDQVDDTSIVVRWSRP 834
             G+KY       N   +S   E   +    +   P     P   T+       I       
Sbjct: 12494 GKKYKFRVAARNAVGVSLPREAEGVYEAKEQLLPPKILMPEQITIKAGKKLRIEAHVYGK 12553

Query: 835   QAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDL--QPGVQYNITIYAVEENQESTPV 892
               P   ++      V  S   ++  ++++ + + D+  +    Y++T             
Sbjct: 12554 PHPTCKWKKGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIK 12613

Query: 893   VIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPG 948
             V+  +  G P+      P D+  ++      ++ W  P     S +T Y V+   V+  G
Sbjct: 12614 VVVMDAPGPPQ-----PPFDISDIDAD--ACSLSWHIPLEDGGSNITNYIVEKCDVS-RG 12665

Query: 949   EHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKL------DAPTN 1002
             +    L     T   V  L PG  Y F+V A +    S+PLT+ +            P N
Sbjct: 12666 DWVTALASVTKTSCRVGKLIPGQEYIFRVRAENRFGISEPLTSPKMVAQFPFGVPSEPKN 12725

Query: 1003  LQFVNETDSTVLVRWTPPRAQ----ITGYRLTVGLTRRGQPRQYNVGPSV---SKYPLRN 1055
              +        + V W  P +     I GY   +    R          ++   ++YP   
Sbjct: 12726 ARVTKVNKDCIFVAWDRPDSDGGSPIIGY--LIERKERNSLLWVKANDTLVRSTEYPCAG 12783

Query: 1056  LQPASEYTVSLVAIKGNQESP--KATGVFTTLQPGSSIPPYNTE---VTETTIVITW 1107
             L    EY+  + A+     SP  K T   T   P    PP   E   VT++T+ + W
Sbjct: 12784 LVEGLEYSFRIYALNKAGSSPPSKPTEYVTARMPVD--PPGKPEVIDVTKSTVSLIW 12838



 Score = 43.9 bits (102), Expect = 0.002
 Identities = 50/204 (24%), Positives = 83/204 (40%), Gaps = 22/204 (10%)

Query: 717   PFSPLVATSESVTEITASSFVVSWVSASDT----VSGFRVEYELSEEGDEPQYLDLPSTA 772
             P  P+V     +  +  +S V+SW   +D     ++ + VE   ++EG E Q +    + 
Sbjct: 24354 PTGPIV-----IEALLKNSAVISWKPPADDGGSWITNYVVEKCEAKEGAEWQLVSSAISV 24408

Query: 773   TSVNIPDLLPGRKYIV-----NVYQISEDGE-QSLILSTSQTTAPDAPPDPTVDQVDDTS 826
             T+  I +L     Y       N + IS+  E  S+++  S    P AP  PT+  V   S
Sbjct: 24409 TTCRIVNLTENAGYYFRVSAQNTFGISDPLEVSSVVIIKSPFEKPGAPGKPTITAVTKDS 24468

Query: 827   IVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSV-TLSDLQPGVQYNITIY 881
              VV W  P     A I  Y +      +     +   E   +V ++ +L  G++Y   + 
Sbjct: 24469 CVVAWKPPASDGGAKIRNYYLEKREKKQNKWISVTTEEIRETVFSVKNLIEGLEYEFRVK 24528

Query: 882   AVEENQESTPVVIQQETTGTPRSD 905
                   ES    I +    TP+SD
Sbjct: 24529 CENLGGESEWSEISEPI--TPKSD 24550



 Score = 41.2 bits (95), Expect = 0.013
 Identities = 92/413 (22%), Positives = 157/413 (38%), Gaps = 51/413 (12%)

Query: 1376  VTWAPPPSID---LTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSV 1432
             ++W PP       +TN++V     K   +   +S + S     + NL     Y   VS+ 
Sbjct: 24370 ISWKPPADDGGSWITNYVVEKCEAKEGAEWQLVSSAISVTTCRIVNLTENAGYYFRVSAQ 24429

Query: 1433  YEQHESTPLRGRQKTGLDSPTGID-------FSDITANSFTVHWIAPRATITGYRIRHHP 1485
                  S PL       + SP            + +T +S  V W  P A+  G +IR++ 
Sbjct: 24430 NTFGISDPLEVSSVVIIKSPFEKPGAPGKPTITAVTKDSCVVAW-KPPASDGGAKIRNYY 24488

Query: 1486  EHFSGRPREDRVPHSRNSITLT-----NLTPGTEYVVSIVA--LNGREESPLLIGQQSTV 1538
                  + +   +  +   I  T     NL  G EY   +    L G  E   +    +  
Sbjct: 24489 LEKREKKQNKWISVTTEEIRETVFSVKNLIEGLEYEFRVKCENLGGESEWSEISEPITPK 24548

Query: 1539  SDVP----------RDLEVVAATPTSLLISWDA-PAVTVRYYRITYGET----GGNSPVQ 1583
             SDVP          R+L V   +  +L+      P   V++YR   G+     G    +Q
Sbjct: 24549 SDVPIQAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYR--QGKEIIADGLKYRIQ 24606

Query: 1584  EFTVPGSKSTATISGLKPGVDYTITVYAV--TGRGDSPASSKPISINYRTEIDKPSQMQ- 1640
             EF   G      I+ +    D   TVY V  T +G S + +  + +    +I  P  ++ 
Sbjct: 24607 EFK--GGYHQLIIASV---TDDDATVYQVRATNQGGSVSGTASLEVEVPAKIHLPKTLEG 24661

Query: 1641  ---VTDVQDNSISVKWLPSSS---PVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQ 1694
                V  ++   +S+K +P S    PV  ++      +  G  +        + +   G++
Sbjct: 24662 MGAVHALRGEVVSIK-IPFSGKPDPVITWQKGQDLIDNNGHYQVIVTRSFTSLVFPNGVE 24720

Query: 1695  PTVEYVVSVYAQNPSGESQPLVQTAVTNI-DRPKGLAFTDVDVDSIKIAWESP 1746
                     V A+N  G  Q  V+  V ++ D P+G+  +DV  DS+ + W  P
Sbjct: 24721 RKDAGFYVVCAKNRFGIDQKTVELDVADVPDPPRGVKVSDVSRDSVNLTWTEP 24773



 Score = 37.7 bits (86), Expect = 0.14
 Identities = 36/131 (27%), Positives = 53/131 (40%), Gaps = 8/131 (6%)

Query: 894   IQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPVNLPGE 949
             I Q+T     +D    PR ++  +V+   V + WT P     S +T Y V+        E
Sbjct: 24737 IDQKTVELDVADVPDPPRGVKVSDVSRDSVNLTWTEPASDGGSKITNYIVEKCATT--AE 24794

Query: 950   HGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQ--TTKLDAPTNLQFVN 1007
                R+  +R T   V  L    +Y F+V A +    SKP    +   TK D    + +  
Sbjct: 24795 RWLRVGQARETRYTVINLFGKTSYQFRVIAENKFGLSKPSEPSEPTITKEDKTRAMNYDE 24854

Query: 1008  ETDSTVLVRWT 1018
             E D T  V  T
Sbjct: 24855 EVDETREVSMT 24865



 Score = 35.0 bits (79), Expect = 0.90
 Identities = 38/169 (22%), Positives = 71/169 (42%), Gaps = 17/169 (10%)

Query: 1610  YAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWL-PSS---SPVTGYRV 1665
             Y V  +       K + ++     D P  ++V+DV  +S+++ W  P+S   S +T Y V
Sbjct: 24727 YVVCAKNRFGIDQKTVELDVADVPDPPRGVKVSDVSRDSVNLTWTEPASDGGSKITNYIV 24786

Query: 1666  TTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPL--VQTAVTNI 1723
                        +   A   +T  T+  L     Y   V A+N  G S+P    +  +T  
Sbjct: 24787 EKCATTAERWLRVGQA--RETRYTVINLFGKTSYQFRVIAENKFGLSKPSEPSEPTITKE 24844

Query: 1724  DRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPD 1772
             D+ + + + D +VD  +        +VS  + ++SS ++   +   A D
Sbjct: 24845 DKTRAMNY-DEEVDETR--------EVSMTKASHSSTKELYEKYMIAED 24884


>gi|110349715 titin isoform N2-B [Homo sapiens]
          Length = 26926

 Score =  175 bits (444), Expect = 4e-43
 Identities = 382/1656 (23%), Positives = 623/1656 (37%), Gaps = 244/1656 (14%)

Query: 630   WNAPQPSHISK---YILRWRPKNSVG--RWKEA--TIPGHLNSYTIKGLKPGVVYEGQLI 682
             W+AP     SK   YI+  +P + VG  RW +   TI    N +T+  L  G  YE +++
Sbjct: 22462 WSAPAYDGGSKVVGYIIERKPVSEVGDGRWLKCNYTIVSD-NFFTVTALSEGDTYEFRVL 22520

Query: 683   SIQQYGHQEVTRFDFTTTSTST-PVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWV 741
             +    G         +  S ST PVT                  + VT    S  V+   
Sbjct: 22521 AKNAAGV-------ISKGSESTGPVTCRDEYAPPKAELDARLHGDLVTIRAGSDLVL--- 22570

Query: 742   SASDTVSGFRVEYELS-EEGDEP---------QYLDLPSTATSVNIPDLLPGRKYIVNVY 791
                D   G + E ++   +GD+          QY    +TA  +   D     KY + V 
Sbjct: 22571 ---DAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAV-IKFCDRSDSGKYTLTVK 22626

Query: 792   QISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ----APITGYRIVYSP 847
               S  G +++ +      +P      TV +V      + WS PQ    A IT Y +    
Sbjct: 22627 NAS--GTKAVSVMVKVLDSPGPCGKLTVSRVTQEKCTLAWSLPQEDGGAEITHYIVERRE 22684

Query: 848   S-------VEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTG 900
             +       VEG    L       S  ++ L    +Y   + AV +     PV  + E   
Sbjct: 22685 TSRLNWVIVEGECPTL-------SYVVTRLIKNNEYIFRVRAVNKYGPGVPV--ESEPIV 22735

Query: 901   TPRSDTVPSPRDL-QFVEVTDVKVTIMWTPPES----AVTGYRVDVIPV-NLPGEHGQRL 954
                S T+PSP  + + V      + I WT PES     ++ Y VD     +L      + 
Sbjct: 22736 ARNSFTIPSPPGIPEEVGTGKEHIIIQWTKPESDGGNEISNYLVDKREKKSLRWTRVNKD 22795

Query: 955   PISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNL-------QFVN 1007
              +  +T  +VT L  G  Y F+V AV+    S+P  A        P+         + V+
Sbjct: 22796 YVVYDTRLKVTSLMEGCDYQFRVTAVNAAGNSEPSEASNFISCREPSYTPGPPSAPRVVD 22855

Query: 1008  ETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSV--SKYPLRNLQPASE 1061
              T  ++ + WT P       I GY L +      Q  + +   ++  +++ + +L+   +
Sbjct: 22856 TTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDTDQWYRVHTNATIRNTEFTVPDLKMGQK 22915

Query: 1062  YT--VSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGV 1119
             Y+  V+ V +KG  E  ++      ++P   I   + E+ +    +  T   R G  L +
Sbjct: 22916 YSFRVAAVNVKGMSEYSES---IAEIEPVERIEIPDLELADD---LKKTVTIRAGASLRL 22969

Query: 1120  RPSQGGEAPREVT-----SDSGSIVVSGLTPGVEYV------------YTIQVLRDGQER 1162
               S  G  P  +T      D  S  +   T     +            YTI+      ++
Sbjct: 22970 MVSVSGRPPPVITWSKQGIDLASRAIIDTTESYSLLIVDKVNRYDAGKYTIEAENQSGKK 23029

Query: 1163  DAPIVNKVV-TPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSL 1221
              A ++ KV  TP   P+    E + D+  +T++WE    P I G      P N       
Sbjct: 23030 SATVLVKVYDTPGPCPSVKVKEVSRDS--VTITWE---IPTIDG----GAPVNNYIVEKR 23080

Query: 1222  EEVVHA-----DQSSCTFDNLSPGLEYNVSVYTVKDDK-----ESVPISDTI-IPEVPQL 1270
             E  + A      + S T   +S  +E  +  + V  +      E    SD + + EVP +
Sbjct: 23081 EAAMRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYGIGEPCETSDAVLVSEVPLV 23140

Query: 1271  -TDLSFVDITDSSIGLRW-TPL--NSSTIIGYRITVVAAGEGIPIFEDFVDSSVGYYTVT 1326
                L  VD+T S++ L W  PL    S + GY +    AG    +    +  +V  +TVT
Sbjct: 23141 PAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGTERWMKVVTLKPTVLEHTVT 23200

Query: 1327  GLEPGIDYDISVITLINGGESAP----TTLT-QQTAVPPPTDLRFTNIGPDTMRV----- 1376
              L  G  Y   +      G S P    T +T Q   V P  DL  + +   T+ V     
Sbjct: 23201 SLNEGEQYLFRIRAQNEKGVSEPRETVTAVTVQDLRVLPTIDL--STMPQKTIHVPAGRP 23258

Query: 1377  -------TWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSV 1429
                       PPP+     F       ++E    E     +   +  T +    EY + +
Sbjct: 23259 VELVIPIAGRPPPAASW--FFAGSKLRESERVTVETHTKVAKLTIRETTIRDTGEYTLEL 23316

Query: 1430  SSVY-EQHESTPLRGRQKTGLDSPTG-IDFSDITANSFTVHWIAPR----ATITGYRIRH 1483
              +V     E+  +    K G   PTG I   +I A S T+ W  P     A ++GY +  
Sbjct: 23317 KNVTGTTSETIKVIILDKPG--PPTGPIKIDEIDATSITISWEPPELDGGAPLSGYVVEQ 23374

Query: 1484  HPEHFSG-RPREDRVPHSRNSITLTNLTPGTEYVVSIVALN----GREESPLLIGQQST- 1537
                H  G  P  + V  +R++   T LT G EYV  + A N    G      +I  +S+ 
Sbjct: 23375 RDAHRPGWLPVSESV--TRSTFKFTRLTEGNEYVFRVAATNRFGIGSYLQSEVIECRSSI 23432

Query: 1538  -VSDVPRDLEVVAATPTSLLISWDAP----AVTVRYYRITYGETGGNSPVQEFTVPGSKS 1592
              +   P  L++   +   + ++W  P       V  Y +   E   +  V+   VP + +
Sbjct: 23433 RIPGPPETLQIFDVSRDGMTLTWYPPEDDGGSQVTGYIVERKEVRADRWVRVNKVPVTMT 23492

Query: 1593  TATISGLKPGVDYTITVYAVTGRGDSPAS--SKPI-SINYRTEIDKPSQMQVTDVQDNSI 1649
                 +GL  G++Y   V A+  RG    S  SKPI +++      KP   +VTD    S+
Sbjct: 23493 RYRSTGLTEGLEYEHRVTAINARGSGKPSRPSKPIVAMDPIAPPGKPQNPRVTDTTRTSV 23552

Query: 1650  SVKWL----PSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYA 1705
             S+ W        S VTGY +     +    TK  T      E T+  L    EY   V A
Sbjct: 23553 SLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTKCNTTPTKIREYTLTHLPQGAEYRFRVLA 23612

Query: 1706  QNPSGESQPLVQTAVTNIDRPKGLAFTDVDVDS-IKIAWESPQGQVSRYRVTYSSPEDGI 1764
              N  G  +P        +   + L + D ++D   +      QG V R  +        I
Sbjct: 23613 CNAGGPGEPAEVPGTVKV--TEMLEYPDYELDERYQEGIFVRQGGVIRLTIPIKGKPFPI 23670

Query: 1765  HELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMES------------QPLIGTQSTA 1812
              +     +G +D ++   +     +T  V+   D  +S            +  +  +   
Sbjct: 23671 CKW--TKEG-QDISKRAMIATSETHTELVIKEADRGDSGTYDLVLENKCGKKAVYIKVRV 23727

Query: 1813  IPAPTD----LKFTQVTPTSLSAQWTPP----NVQLTGYRV--RVTPKEKTGPMKEINLA 1862
             I +P      L++  +   S+   W PP       + GY +  R  PK        I+  
Sbjct: 23728 IGSPNSPEGPLEYDDIQVRSVRVSWRPPADDGGADILGYILERREVPK---AAWYTIDSR 23784

Query: 1863  PDSSSVVVSGLMVATKYEVSVYALKDTLTSRP--AQGVVTTLENVSPP----RRARVTDA 1916
                +S+VV GL    +Y   V A      S+P  ++  VT    ++PP        V D 
Sbjct: 23785 VRGTSLVVKGLKENVEYHFRVSAENQFGISKPLKSEEPVTPKTPLNPPEPPSNPPEVLDV 23844

Query: 1917  TETTITISW-RTKTE---TITGFQVDAVPANGQTPIQRT-IKPDVRSYTITGLQPGTDYK 1971
             T++++++SW R K +    +TG+ ++    +    ++    +     YT+TGL P  +Y+
Sbjct: 23845 TKSSVSLSWSRPKDDGGSRVTGYYIERKETSTDKWVRHNKTQITTTMYTVTGLVPDAEYQ 23904

Query: 1972  IYLYTLND------NARSSPVVI-DASTAIDAPSNLRFLATTPNSLLVSWQPPRA----R 2020
               +   ND      +  S PVV  D       P  L  L+ + +S+ + W+ P       
Sbjct: 23905 FRIIAQNDVGLSETSPASEPVVCKDPFDKPSQPGELEILSISKDSVTLQWEKPECDGGKE 23964

Query: 2021  ITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRK 2080
             I GY ++Y + G    +   + R    + TI GL   TEY   V A      S P     
Sbjct: 23965 ILGYWVEYRQSGDSAWKKSNKERIKDKQFTIGGLLEATEYEFRVFAENETGLSRP----- 24019

Query: 2081  KTVQKTPFVTHPGYDTGNGIQLPGTSGQQPSVGQQM 2116
                            T   I+   TSG+ P + ++M
Sbjct: 24020 -------------RRTAMSIKTKLTSGEAPGIRKEM 24042



 Score =  157 bits (398), Expect = 9e-38
 Identities = 342/1617 (21%), Positives = 590/1617 (36%), Gaps = 235/1617 (14%)

Query: 624   NSHPIQWNAPQP---SHISKYILRWRPKNSVGRWKEAT-IPGHLNSYTIKGLKPGVVYEG 679
             N+  + W  P     S I+ Y +  R K S+ RW  A   P       + GL+ G  YE 
Sbjct: 14089 NTATVSWKRPVDDGGSEITGYHVERREKKSL-RWVRAIKTPVSDLRCKVTGLQEGSTYEF 14147

Query: 680   QLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVS 739
             ++ +  + G    +              S++V  +   + P   ++  VT+ T  S  ++
Sbjct: 14148 RVSAENRAGIGPPSE------------ASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLA 14195

Query: 740   W----VSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVN---IPDLLPGRKYIVNVYQ 792
             W          ++G+ VE++  + GDE    D   TA  +    +PDL    KY   +  
Sbjct: 14196 WGKPHYDGGLEITGYVVEHQ--KVGDEAWIKDTTGTALRITQFVVPDLQTKEKYNFRISA 14253

Query: 793   ISEDGE-QSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWS---RPQAPITGYRIVYSPS 848
             I++ G  +  ++   +    +  PD  +D     ++VVR     R   PI G     +P 
Sbjct: 14254 INDAGVGEPAVIPDVEIVEREMAPDFELDAELRRTLVVRAGLSIRIFVPIKGRP---APE 14310

Query: 849   VEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTV- 907
             V  +   +NL   AN      ++    + + I       ++   V+  E     +S  V 
Sbjct: 14311 VTWTKDNINLKNRAN------IENTESFTLLIIPECNRYDTGKFVMTIENPAGKKSGFVN 14364

Query: 908   ------PSP-RDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPGEHGQRLPI 956
                   P P  +L+  ++T   VT+ W  P     S +T Y V+                
Sbjct: 14365 VRVLDTPGPVLNLRPTDITKDSVTLHWDLPLIDGGSRITNYIVEKREATRKSYSTATTKC 14424

Query: 957   SRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDA----PTNLQFVNETDST 1012
              + T+ +VTGLS G  Y+F+V A +     +P    +  K       P +L  ++ T ST
Sbjct: 14425 HKCTY-KVTGLSEGCEYFFRVMAENEYGIGEPTETTEPVKASEAPSPPDSLNIMDITKST 14483

Query: 1013  VLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSVS-KYPLRNLQPASEYTVSLV 1067
             V + W  P+    ++ITGY   +   R+G  +  ++      +  +RNL    EYT  ++
Sbjct: 14484 VSLAWPKPKHDGGSKITGY--VIEAQRKGSDQWTHITTVKGLECVVRNLTEGEEYTFQVM 14541

Query: 1068  AIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWT-------------PAPRIG 1114
             A+     S         ++  + +P  +       +VI                P P + 
Sbjct: 14542 AVNSAGRSAPRESRPVIVKEQTMLPELDLRGIYQKLVIAKAGDNIKVEIPVLGRPKPTVT 14601

Query: 1115  FKLGVRP-SQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTP 1173
             +K G +   Q      E T+ S  + ++         Y +       E    I  +V   
Sbjct: 14602 WKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLTARNIVGEVGDVITIQVHDI 14661

Query: 1174  LSPPTNLHLEANPDTGVLTVSW---ERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQS 1230
               PPT         +  +T SW   E      I+ Y +    T+      L   V     
Sbjct: 14662 PGPPTGPIKFDEVSSDFVTFSWDPPENDGGVPISNYVVEMRQTDSTTWVELATTVIRTTY 14721

Query: 1231  SCTFDNLSPGLEYNVSVYTVKDDKESVPISDTII-----------PEVPQLTDLSFVDIT 1279
               T   L+ GLEY   V           I+   I           P  PQ+T      +T
Sbjct: 14722 KAT--RLTTGLEYQFRVKAQNRYGVGPGITSACIVANYPFKVPGPPGTPQVTA-----VT 14774

Query: 1280  DSSIGLRW-TPLNS--STIIGYRITVVAAGEGIPIFEDFVDSSV---GYYTVTGLEPGID 1333
               S+ + W  PL+   S I+GY    V   E   I    V  ++     +  +GL  GI 
Sbjct: 14775 KDSMTISWHEPLSDGGSPILGYH---VERKERNGILWQTVSKALVPGNIFKSSGLTDGIA 14831

Query: 1334  YDISVITLINGGESAPTTLTQQTA----VPPPTDLRFTNIGPDTMRVTWAPPP---SIDL 1386
             Y+  VI     G+S P+  ++       + PP      NI   T+ + WA P       +
Sbjct: 14832 YEFRVIAENMAGKSKPSKPSEPMLALDPIDPPGKPVPLNITRHTVTLKWAKPEYTGGFKI 14891

Query: 1387  TNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQ- 1445
             T+++V    + N   +     +  +N   ++ L     Y   V +       +P      
Sbjct: 14892 TSYIVEKRDLPNGRWLKANFSNILENEFTVSGLTEDAAYEFRVIAKNAAGAISPPSEPSD 14951

Query: 1446  ----KTGLDSP---TGIDFSDIT----ANSF------------TVHWIAPRATITGY-RI 1481
                 +  +++P     + F D        +F            T+ W      + G  ++
Sbjct: 14952 AITCRDDVEAPKIKVDVKFKDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKL 15011

Query: 1482  RHHPEHFSGR-PREDRVPHSRNSITLTNLTPG--TEYVVSIVALN--GREESPLLIGQQS 1536
                   FS     +D       + TLT   PG   +++ ++  L+  G  E PL + +  
Sbjct: 15012 EIKIADFSTNLVNKDSTRRDSGAYTLTATNPGGFAKHIFNVKVLDRPGPPEGPLAVTE-- 15069

Query: 1537  TVSDVPRDLEVVAATPTSLLISWDAP----AVTVRYYRITYGETGGNSPVQEFTVPGSKS 1592
                           T    ++SW  P       + +Y +   ET   +    +T   S+ 
Sbjct: 15070 -------------VTSEKCVLSWFPPLDDGGAKIDHYIVQKRETSRLA----WTNVASEV 15112

Query: 1593  TAT---ISGLKPGVDYTITVYAVTGRG-DSPASSKPI-SINYRTEIDKPSQMQVTDVQDN 1647
               T   ++ L  G +Y   V AV   G   P  S+P+ ++N     D P   +VT +  +
Sbjct: 15113 QVTKLKVTKLLKGNEYIFRVMAVNKYGVGEPLESEPVLAVNPYGPPDPPKNPEVTTITKD 15172

Query: 1648  SISVKW----LPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSV 1703
             S+ V W        S +  Y V    K G    K            + GL    EY   +
Sbjct: 15173 SMVVCWGHPDSDGGSEIINYIVERRDKAGQRWIKCNKKTLTDLRYKVSGLTEGHEYEFRI 15232

Query: 1704  YAQNPSGESQPLVQT-------AVTNIDRPKGLAFTDVDVDSIKIAWESP----QGQVSR 1752
              A+N +G S P   +        V     P      D    SI IAW  P      +++ 
Sbjct: 15233 MAENAAGISAPSPTSPFYKACDTVFKPGPPGNPRVLDTSRSSISIAWNKPIYDGGSEITG 15292

Query: 1753  YRVTYSSPEDGIHELFPAPDGEEDTA-ELQGLRPGSEYTVSVVALHDDMESQPLI--GT- 1808
             Y V  + PE+   ++   P G + T+  + GL    EY + + A++ +   +P +  GT 
Sbjct: 15293 YMVEIALPEEDEWQIVTPPAGLKATSYTITGLTENQEYKIRIYAMNSEGLGEPALVPGTP 15352

Query: 1809  --QSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSS 1866
               +   +P   +L        ++ A  T          +R+    K  P  E+  A D  
Sbjct: 15353 KAEDRMLPPEIELDADLRKVVTIRACCT----------LRLFVPIKGRPAPEVKWARDHG 15402

Query: 1867  SVVVSGLMVAT------------KYEVSVYAL--KDTLTSRPAQGVVTTLENVSPPRRAR 1912
               +    + +T            +++   Y L  +++  S+ A   V  L+   PP+  +
Sbjct: 15403 ESLDKASIESTSSYTLLIVGNVNRFDSGKYILTVENSSGSKSAFVNVRVLDTPGPPQDLK 15462

Query: 1913  VTDATETTITISWRTKT----ETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGT 1968
             V + T+T++T++W          I  + V+   +  +            S+ +  LQ G 
Sbjct: 15463 VKEVTKTSVTLTWDPPLLDGGSKIKNYIVEKRESTRKAYSTVATNCHKTSWKVDQLQEGC 15522

Query: 1969  DYKIYLYTLNDNARSSPVVIDASTAIDA------PSNLRFLATTPNSLLVSWQPPR---- 2018
              Y  Y   L +N     +  + + ++ A      P  +  +  T NS+ +SW+ P     
Sbjct: 15523 SY--YFRVLAENEYGIGLPAETAESVKASERPLPPGKITLMDVTRNSVSLSWEKPEHDGG 15580

Query: 2019  ARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEP 2075
             +RI GYI++ +  GS         +  VTEATITGL  G EY+  V A      S+P
Sbjct: 15581 SRILGYIVEMQTKGSDKWATCATVK--VTEATITGLIQGEEYSFRVSAQNEKGISDP 15635



 Score =  146 bits (368), Expect = 3e-34
 Identities = 363/1662 (21%), Positives = 600/1662 (36%), Gaps = 237/1662 (14%)

Query: 612  VEVFITETPSQPNSHPIQ----------WNAPQP---SHISKYILRWRPKNSVGRWKEAT 658
            VEV + + P  P +  I           WN P+    S I+ Y++  R  +S   W + +
Sbjct: 7279 VEVNVLDKPGPPAAFDITDVTNESCLLTWNPPRDDGGSKITNYVVERRATDSEV-WHKLS 7337

Query: 659  IPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPF 718
                  ++    L P   Y  ++ +   YG  E             PV ++ +T +    
Sbjct: 7338 STVKDTNFKATKLIPNKEYIFRVAAENMYGVGE-------------PVQASPITAKYQFD 7384

Query: 719  SPLVATSESVTEITASSFVVSWVSASDT----VSGFRVEYELSEEGDEPQYLDLPSTATS 774
             P   T    ++IT  +  ++W    D     ++G+ VE    +     +   +P   T+
Sbjct: 7385 PPGPPTRLEPSDITKDAVTLTWCEPDDDGGSPITGYWVERLDPDTDKWVRCNKMPVKDTT 7444

Query: 775  VNIPDLLPGRKYIVNVY--QISEDGEQSL----ILSTSQTTAPDAPPDPTVDQVDDTSIV 828
              +  L   +KY   V    ++  G+ S     IL       P  P  PTV  V  TS+ 
Sbjct: 7445 YRVKGLTNKKKYRFRVLAENLAGPGKPSKSTEPILIKDPIDPPWPPGKPTVKDVGKTSVR 7504

Query: 829  VRWSRPQ----APITGY--RIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYA 882
            + W++P+    A I  Y   ++ + + E       +P T +   L  L  G +Y+  + A
Sbjct: 7505 LNWTKPEHDGGAKIESYVIEMLKTGTDEWVRVAEGVPTTQH--LLPGLMEGQEYSFRVRA 7562

Query: 883  VEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYR 938
            V +  ES P           +      PR L+ + +T     + WT PE    S +T Y 
Sbjct: 7563 VNKAGESEPSEPSDPVLCREKLYPPSPPRWLEVINITKNTADLKWTVPEKDGGSPITNYI 7622

Query: 939  VDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSH-GR------ESKPLTA 991
            V+   V   G       + ++T   VT L+ G  Y F+V A +  G+      E   L  
Sbjct: 7623 VEKRDVRRKGWQTVDTTV-KDTKCTVTPLTEGSLYVFRVAAENAIGQSDYTEIEDSVLAK 7681

Query: 992  QQTTKLDAPTNLQFVNETDSTVLVRWTPPR--AQITGYRLTVGLTRRGQPRQYNVGPSVS 1049
               T    P  L  V+ T   V ++W PP+        R  +    R   R    G +  
Sbjct: 7682 DTFTTPGPPYALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKERLGTRWVKAGKTAG 7741

Query: 1050 KYPLRNLQPASEYTVSLVAIKGNQES-----PKATGVFTTLQPGS-SIPPYNTEVTET-- 1101
                  +    E T     ++   E+      + T + +   P S   PP +  VT+   
Sbjct: 7742 PDCNFRVTDVIEGTEVQFQVRAENEAGVGHPSEPTEILSIEDPTSPPSPPLDLHVTDAGR 7801

Query: 1102 -TIVITWTP------APRIGFKLGVRPSQGGEAPREVTS----DSGSIVVSGLTPGVEYV 1150
              I I W P      +P IG+ + + P  G E    V S    D    V  G+ P  EYV
Sbjct: 7802 KHIAIAWKPPEKNGGSPIIGYHVEMCP-VGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYV 7860

Query: 1151 YTIQVLRD-GQERDAPIVNKVVT--PLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYR 1207
              ++ +   G    + I   VV   P   PT + LE +    ++ +  E+ + P    +R
Sbjct: 7861 LRVRAVNAIGVSEPSEISENVVAKDPDCKPT-IDLETH---DIIVIEGEKLSIP--VPFR 7914

Query: 1208 ITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEY------NVSVYTV----KDDKESV 1257
                PT     +  +EV  +D+ +   D++S  LE       +  +YT+    K    + 
Sbjct: 7915 AVPVPTVSWHKDG-KEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATA 7973

Query: 1258 PISDTIIPEVPQLTDLSFVDITDSSIGLRWTPL---NSSTIIGYRITVVAAGEG--IPIF 1312
             I+  +I       D+   DIT SS  L W P      + I+ Y +    AG    IP+ 
Sbjct: 7974 SINVKVIGLPGPCKDIKASDITKSSCKLTWEPPEFDGGTPILHYVLERREAGRRTYIPVM 8033

Query: 1313 EDFVDSSVGYYTVTGLEPGIDY--DISVITLINGGESAP---TTLTQQTAVP--PPTDLR 1365
                  S   +TV  L P  +Y   +  +  + GGE        + Q    P  PP D+ 
Sbjct: 8034 SGENKLS---WTVKDLIPNGEYFFRVKAVNKVGGGEYIELKNPVIAQDPKQPPDPPVDVE 8090

Query: 1366 FTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLT----NLLP 1421
              N   + M +TW  PP  D  + ++ Y   K  +              +LT     L  
Sbjct: 8091 VHNPTAEAMTITW-KPPLYDGGSKIMGYIIEKIAKGEERWKRCNEHLVPILTYTAKGLEE 8149

Query: 1422 GTEYVVSVSSVYEQHESTPLRGRQKT----GLDSP---------------TGIDFSDITA 1462
            G EY   V +      S P R    T     +D+P                 +D S   +
Sbjct: 8150 GKEYQFRVRAENAAGISEPSRATPPTKAVDPIDAPKVILRTSLEVKRGDEIALDASISGS 8209

Query: 1463 NSFTVHWIAPRATITGYRIRHHPEHFSGRPR------EDRVPHSRNSITLTNLTPGTE-- 1514
               T+ WI     I    I+        R +      E  V      +++ N   G    
Sbjct: 8210 PYPTITWIKDENVIVPEEIKKRAAPLVRRRKGEVQEEEPFVLPLTQRLSIDNSKKGESQL 8269

Query: 1515 ------------YVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAP 1562
                        Y++ +   +G  ++P  +    T    P +        TS+L  W+ P
Sbjct: 8270 RVRDSLRPDHGLYMIKVENDHGIAKAPCTVSVLDTPGP-PINFVFEDIRKTSVLCKWEPP 8328

Query: 1563 -----AVTVRYYRITYGETGGNSPVQEFTVPGS---KSTATISGLKPGVDYTITVYAVTG 1614
                 +  + Y   T  +     P  E+ V  S       +++ L  G +Y   V A   
Sbjct: 8329 LDDGGSEIINY---TLEKKDKTKPDSEWIVVTSTLRHCKYSVTKLIEGKEYLFRVRAENR 8385

Query: 1615 RGDS-PASSKP-ISINYRTEIDKPSQMQVTDVQDNSISVKW---LPSSSPVTGYRVTTTP 1669
             G   P  SKP ++ +     D P +  V DV  NS+ VKW     + SP+ GY +    
Sbjct: 8386 FGPGPPCVSKPLVAKDPFGPPDAPDKPIVEDVTSNSMLVKWNEPKDNGSPILGYWLEKRE 8445

Query: 1670 KNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSG------ESQPLVQTAVTNI 1723
             N    ++   +  +  +  ++GL   + YV  V A+N +G       S P       + 
Sbjct: 8446 VNSTHWSRVNKSLLNALKANVDGLLEGLTYVFRVCAENAAGPGKFSPPSDPKTAHDPISP 8505

Query: 1724 DRPKGLAFTDVDVDSIKIAWESPQ----GQVSRYRVTYSSPEDGIHELFPAPDGEEDTAE 1779
              P     TD    +I++ WE P     G++  Y V       G +E     +      +
Sbjct: 8506 PGPPIPRVTDTSSTTIELEWEPPAFNGGGEIVGYFV--DKQLVGTNEWSRCTEKMIKVRQ 8563

Query: 1780 --LQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPN 1837
              ++ +R G++Y + V A++   E  P   TQ   +  P +    ++  +          
Sbjct: 8564 YTVKEIREGADYKLRVSAVNAAGEGPP-GETQPVTVAEPQEPPAVELDVS------VKGG 8616

Query: 1838 VQLTGYRVRVTPKEKTG---PMKEINLAP---DSSSVVVSGLMVATKYEVSVYALKDTLT 1891
            +Q+   +    P   TG   P K         D   VV+    V TK E+    +KD L 
Sbjct: 8617 IQIMAGKTLRIPAVVTGRPVPTKVWTKEEGELDKDRVVIDN--VGTKSEL---IIKDALR 8671

Query: 1892 SRPAQGVVTTLENVS---PPRRARVTDATETTI------------TISWRTKTE----TI 1932
                + V+T   +        R  V D     +             ++W    +     I
Sbjct: 8672 KDHGRYVITATNSCGSKFAAARVEVFDVPGPVLDLKPVVTNRKMCLLNWSDPEDDGGSEI 8731

Query: 1933 TGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDAST 1992
            TGF ++   A   T  ++ I+ +     ITGL  G +YK  +   N      PV I    
Sbjct: 8732 TGFIIERKDAKMHT-WRQPIETERSKCDITGLLEGQEYKFRVIAKNKFGCGPPVEIGPIL 8790

Query: 1993 AID------APSNLRFLATTPNSLLVSWQPPRAR----ITGYIIKYEKPGSPPREVVPRP 2042
            A+D      +P  L +   T +++ + W+ PR+     I GYII+  +   P  E V + 
Sbjct: 8791 AVDPLGPPTSPERLTYTERTKSTITLDWKEPRSNGGSPIQGYIIEKRRHDKPDFERVNKR 8850

Query: 2043 RPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQ 2084
                T   +  L+    Y   V A+    +SEP +     +Q
Sbjct: 8851 LCPTTSFLVENLDEHQMYEFRVKAVNEIGESEPSLPLNVVIQ 8892



 Score =  144 bits (362), Expect = 1e-33
 Identities = 288/1427 (20%), Positives = 522/1427 (36%), Gaps = 163/1427 (11%)

Query: 696   DFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYE 755
             D+T T+ ++  + +          P    S  + ++ +   ++SW    +        Y 
Sbjct: 12868 DYTITAENSSGSKSATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYI 12927

Query: 756   LSE-EGDEPQYLDLPSTA--TSVNIPDLLPGRKY-----IVNVYQISEDGEQSLILSTSQ 807
             + + E   P +  + +T   TS ++  L+ G +Y       N Y + +       ++ + 
Sbjct: 12928 VDKRETSRPNWAQVSATVPITSCSVEKLIEGHEYQFRICAENKYGVGDPVFTEPAIAKNP 12987

Query: 808   TTAPDAPPDPTVDQVDDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNL-PETA 862
                P     P +  +    + V W  P     +PITGY +    +   + T++N  P   
Sbjct: 12988 YDPPGRCDPPVISNITKDHMTVSWKPPADDGGSPITGYLLEKRETQAVNWTKVNRKPIIE 13047

Query: 863   NSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVK 922
              ++  + LQ G +Y   + A+ +     P    +             P   +  + T   
Sbjct: 13048 RTLKATGLQEGTEYEFRVTAINKAGPGKPSDASKAAYARDPQYPPGPPAFPKVYDTTRSS 13107

Query: 923   VTIMWTPPE----SAVTGYRVDVIPVNLPGEHGQRLPIS-RNTFAEVTGLSPGVTYYFKV 977
             V++ W  P     S + GY V+V   +        LP + + T  EVTGL     Y F+V
Sbjct: 13108 VSLSWGKPAYDGGSPIIGYLVEVKRADSDNWVRCNLPQNLQKTRFEVTGLMEDTQYQFRV 13167

Query: 978   FAVSHGRESKP-----------LTAQQTTKLDAPTNLQFVNETDST----VLVRWTPPRA 1022
             +AV+    S P           +      +LDA      +     T    V V+  PP  
Sbjct: 13168 YAVNKIGYSDPSDVPDKHYPKDILIPPEGELDADLRKTLILRAGVTMRLYVPVKGRPP-P 13226

Query: 1023  QITGYRLTVGLTRR-GQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGV 1081
             +IT  +  V L  R G   +     +  +    N   A +Y ++L    G +E      V
Sbjct: 13227 KITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKYILTLENSCGKKEYTIVVKV 13286

Query: 1082  FTTLQPGSSIPPYNTEVTETTIVITWTP------APRIGFKLGVRPSQGGEAPREVTSDS 1135
               T  PG  +     E+++ +  +TW P      +P I + +  R ++        T  S
Sbjct: 13287 LDT--PGPPVNVTVKEISKDSAYVTWEPPIIDGGSPIINYVVQKRDAERKSWSTVTTECS 13344

Query: 1136  -GSIVVSGLTPGVEYVYTIQVLRD------GQERDAPIVNKVVTPLSPPTNLHLEANPDT 1188
               S  V+ L  G  Y + +    +      G+ RDA  V    TP  P  +L + +   +
Sbjct: 13345 KTSFRVANLEEGKSYFFRVFAENEYGIGDPGETRDA--VKASQTP-GPVVDLKVRSVSKS 13401

Query: 1189  GVLTVSWERSTTPD---ITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNV 1245
                ++ W++  +     I GY +        + N  + V+ +     +  +L+ G EY  
Sbjct: 13402 S-CSIGWKKPHSDGGSRIIGYVVDFL----TEENKWQRVMKSLSLQYSAKDLTEGKEYTF 13456

Query: 1246  SVYTVKDDKESVPISDTIIP---------EVPQLTDLSFVDITDSSIGLR---------- 1286
              V    ++ E  P   T++          ++  L DL ++   +S+  L+          
Sbjct: 13457 RVSAENENGEGTPSEITVVARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPIKGKPAPS 13516

Query: 1287  --WTPLNSSTIIGYRITVVAAGEGIP-IFEDFVDSSVGYYTVTGLEPGIDYDISVITLIN 1343
               W           R++V ++      I  D   S  G YT+T        + ++   + 
Sbjct: 13517 VSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKEGTISIKVV 13576

Query: 1344  GGESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAPPP---SIDLTNFLVRYSPVKNEE 1400
             G    PT             ++F  +  + M + WAPP      ++TN+++      N +
Sbjct: 13577 GKPGIPT-----------GPIKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDSVNNK 13625

Query: 1401  DVAELSISPSDNAVVLTNLLPGTEYVVSVSS-----VYEQHESTPLRGRQKTGL-DSPTG 1454
              V   S +       +T L  G EY   VS+     V E  +S P+  R    + D+P  
Sbjct: 13626 WVTCAS-AVQKTTFRVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVPDAPPP 13684

Query: 1455  IDFSDITANSFTVHWIAPRAT----ITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLT 1510
              +  D+  +S ++ W  P+ T    ITGY +     +     R ++ P       +T LT
Sbjct: 13685 PNIVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTPIRMRDFKVTGLT 13744

Query: 1511  PGTEYVVSIVALN----GREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAV-- 1564
              G EY   ++A+N    G+   P          D P   EV+  T  S+ + W  P    
Sbjct: 13745 EGLEYEFRVMAINLAGVGKPSLPSEPVVALDPIDPPGKPEVINITRNSVTLIWTEPKYDG 13804

Query: 1565  --TVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASS 1622
                +  Y +   +    S ++   V   +   T++ L  G  Y   + A    G   A S
Sbjct: 13805 GHKLTGYIVEKRDLPSKSWMKANHVNVPECAFTVTDLVEGGKYEFRIRAKNTAGAISAPS 13864

Query: 1623  KPI-SINYRTEIDKPSQMQVTDVQD------------NSISV--KWLPSSS-PVTGYRVT 1666
             +   +I  + E + P+ +    ++D            N+IS+  K LP SS    G  + 
Sbjct: 13865 ESTETIICKDEYEAPTIVLDPTIKDGLTIKAGDTIVLNAISILGKPLPKSSWSKAGKDIR 13924

Query: 1667  TTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRP 1726
                   P      T+ P  + +TI+          ++ A NP G     V+  V ++  P
Sbjct: 13925 ------PSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFGTKVEHVKVTVLDVPGP 13978

Query: 1727  KG-LAFTDVDVDSIKIAWESP---QGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQG 1782
              G +  ++V  +   + W  P    G   +  +        +     + D +        
Sbjct: 13979 PGPVEISNVSAEKATLTWTPPLEDGGSPIKSYILEKRETSRLLWTVVSEDIQSCRHVATK 14038

Query: 1783  LRPGSEYTVSVVALH-----DDMESQPLIGTQSTAIPAPTDL-KFTQVTPTSLSAQWTPP 1836
             L  G+EY   V A++     + ++S+P+        P P +  + + VT  + +  W  P
Sbjct: 14039 LIQGNEYIFRVSAVNHYGKGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSWKRP 14098

Query: 1837  ----NVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTS 1892
                   ++TGY V    K+    ++ I          V+GL   + YE  V A       
Sbjct: 14099 VDDGGSEITGYHVERREKKSLRWVRAIKTPVSDLRCKVTGLQEGSTYEFRVSAENRAGIG 14158

Query: 1893  RPAQGVVTTLEN-----VSPPRRARVTDATETTITISWRTKTE----TITGFQVDAVPAN 1943
              P++   + L         PP    VTD T+ + +++W          ITG+ V+     
Sbjct: 14159 PPSEASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLAWGKPHYDGGLEITGYVVEHQKVG 14218

Query: 1944  GQTPIQRTIKPDVR--SYTITGLQPGTDYKIYLYTLNDNARSSPVVI 1988
              +  I+ T    +R   + +  LQ    Y   +  +ND     P VI
Sbjct: 14219 DEAWIKDTTGTALRITQFVVPDLQTKEKYNFRISAINDAGVGEPAVI 14265



 Score =  136 bits (342), Expect = 3e-31
 Identities = 287/1435 (20%), Positives = 516/1435 (35%), Gaps = 196/1435 (13%)

Query: 794   SEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ----APITGYRIVYSPSV 849
             +  G +S  +       P  P    ++++     ++ W  P     + IT Y +    + 
Sbjct: 12875 NSSGSKSATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYIVDKRETS 12934

Query: 850   EGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPS 909
               +  +++      S ++  L  G +Y   I A  +     PV  +      P     P 
Sbjct: 12935 RPNWAQVSATVPITSCSVEKLIEGHEYQFRICAENKYGVGDPVFTEPAIAKNPYDP--PG 12992

Query: 910   PRDLQFVE-VTDVKVTIMWTPPE----SAVTGYRVDVIPVNLPG-EHGQRLPISRNTFAE 963
               D   +  +T   +T+ W PP     S +TGY ++             R PI   T  +
Sbjct: 12993 RCDPPVISNITKDHMTVSWKPPADDGGSPITGYLLEKRETQAVNWTKVNRKPIIERTL-K 13051

Query: 964   VTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKL-------DAPTNLQFVNETDSTVLVR 1016
              TGL  G  Y F+V A++     KP  A +             P   +  + T S+V + 
Sbjct: 13052 ATGLQEGTEYEFRVTAINKAGPGKPSDASKAAYARDPQYPPGPPAFPKVYDTTRSSVSLS 13111

Query: 1017  WTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSVSK--YPLRNLQPASEYTVSLVAIK 1070
             W  P     + I GY + V         + N+  ++ K  + +  L   ++Y   + A+ 
Sbjct: 13112 WGKPAYDGGSPIIGYLVEVKRADSDNWVRCNLPQNLQKTRFEVTGLMEDTQYQFRVYAVN 13171

Query: 1071  GNQESPKATGVFTTLQPGSSIPP---YNTEVTETTIVITWTPAPRIGFKLGVRPSQGGEA 1127
                 S  +            IPP    + ++ +T I+       R G  + +     G  
Sbjct: 13172 KIGYSDPSDVPDKHYPKDILIPPEGELDADLRKTLIL-------RAGVTMRLYVPVKGRP 13224

Query: 1128  PREVTSDSGSIVVS---GLT------------------PGVEYVYTIQVLRDGQERDAPI 1166
             P ++T    ++ +    GL                      +Y+ T++      +++  I
Sbjct: 13225 PPKITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKYILTLE--NSCGKKEYTI 13282

Query: 1167  VNKVVTPLSPPTNLHL-EANPDTGVLTVSWERSTTPDITG----YRITTTPTNGQQGNSL 1221
             V KV+    PP N+ + E + D+  +T  WE    P I G            + ++ +  
Sbjct: 13283 VVKVLDTPGPPVNVTVKEISKDSAYVT--WE---PPIIDGGSPIINYVVQKRDAERKSWS 13337

Query: 1222  EEVVHADQSSCTFDNLSPGLEYNVSVYTVKD--------DKESVPISDTIIPEVPQLTDL 1273
                    ++S    NL  G  Y   V+   +         +++V  S T  P V    DL
Sbjct: 13338 TVTTECSKTSFRVANLEEGKSYFFRVFAENEYGIGDPGETRDAVKASQTPGPVV----DL 13393

Query: 1274  SFVDITDSSIGLRWTPLNS---STIIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEP 1330
                 ++ SS  + W   +S   S IIGY +  +        ++  + S    Y+   L  
Sbjct: 13394 KVRSVSKSSCSIGWKKPHSDGGSRIIGYVVDFLTEENK---WQRVMKSLSLQYSAKDLTE 13450

Query: 1331  GIDYDISVITLINGGESAPTTLT---QQTAVPPPTDLRFTNIGPDT-------------M 1374
             G +Y   V      GE  P+ +T   +   V P  DL+     PD              +
Sbjct: 13451 GKEYTFRVSAENENGEGTPSEITVVARDDVVAPDLDLKGL---PDLCYLAKENSNFRLKI 13507

Query: 1375  RVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLL-------PGTEYVV 1427
              +   P PS+         S  K E+ +A  +    +++ V T L+          +Y +
Sbjct: 13508 PIKGKPAPSV---------SWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTI 13558

Query: 1428  SVSSVYEQHEST-PLRGRQKTGLDSPTG-IDFSDITANSFTVHWIAPR----ATITGYRI 1481
             ++ +V    E T  ++   K G+  PTG I F ++TA + T+ W  P+    + IT Y I
Sbjct: 13559 TLKNVAGTKEGTISIKVVGKPGI--PTGPIKFDEVTAEAMTLKWAPPKDDGGSEITNY-I 13615

Query: 1482  RHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN------GREESPLLIGQQ 1535
                 +  + +         + +  +T L  G EY   + A N      G +  P++    
Sbjct: 13616 LEKRDSVNNKWVTCASAVQKTTFRVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHP 13675

Query: 1536  STVSDVPRDLEVVAATPTSLLISWDAPAVT----VRYYRITYGETGGNSPVQEFTVPGSK 1591
               V D P    +V     S+ ++W  P  T    +  Y + + E       +    P   
Sbjct: 13676 FDVPDAPPPPNIVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTPIRM 13735

Query: 1592  STATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISV 1651
                 ++GL  G++Y   V A+   G    S     +     ID P + +V ++  NS+++
Sbjct: 13736 RDFKVTGLTEGLEYEFRVMAINLAGVGKPSLPSEPVVALDPIDPPGKPEVINITRNSVTL 13795

Query: 1652  KWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQN 1707
              W          +TGY V           K       +   T+  L    +Y   + A+N
Sbjct: 13796 IWTEPKYDGGHKLTGYIVEKRDLPSKSWMKANHVNVPECAFTVTDLVEGGKYEFRIRAKN 13855

Query: 1708  PSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQV----------------S 1751
              +G      ++  T I + +  A T V   +IK       G                  S
Sbjct: 13856 TAGAISAPSESTETIICKDEYEAPTIVLDPTIKDGLTIKAGDTIVLNAISILGKPLPKSS 13915

Query: 1752  RYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQST 1811
               +         I ++   P     T +    +   EYT++             +     
Sbjct: 13916 WSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFGTKVEHVKVTVLDV 13975

Query: 1812  AIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVR--VTPKEKTGPMKEINLAPDSSSV- 1868
               P P  ++ + V+    +  WTPP ++  G  ++  +  K +T  +    ++ D  S  
Sbjct: 13976 PGP-PGPVEISNVSAEKATLTWTPP-LEDGGSPIKSYILEKRETSRLLWTVVSEDIQSCR 14033

Query: 1869  -VVSGLMVATKYEVSVYALKDTLTSRPAQG----VVTTLENVSPPRRARVTDATETTITI 1923
              V + L+   +Y   V A+       P Q     +V       PP +  V++ T+ T T+
Sbjct: 14034 HVATKLIQGNEYIFRVSAVNHYGKGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTATV 14093

Query: 1924  SWRTKTE----TITGFQVDAVPANGQTPIQRTIKPDVRSY--TITGLQPGTDYKIYLYTL 1977
             SW+   +     ITG+ V+         + R IK  V      +TGLQ G+ Y+  +   
Sbjct: 14094 SWKRPVDDGGSEITGYHVERREKKSLRWV-RAIKTPVSDLRCKVTGLQEGSTYEFRVSAE 14152

Query: 1978  N-------DNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYII 2026
             N         A  S ++ DA+     PSN     TT  S  ++W  P       ITGY++
Sbjct: 14153 NRAGIGPPSEASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLAWGKPHYDGGLEITGYVV 14212

Query: 2027  KYEKPGSPPREVVPRPRPG----VTEATITGLEPGTEYTIYVIALKNNQKSEPLI 2077
             +++K G    E   +   G    +T+  +  L+   +Y   + A+ +    EP +
Sbjct: 14213 EHQKVGD---EAWIKDTTGTALRITQFVVPDLQTKEKYNFRISAINDAGVGEPAV 14264



 Score =  133 bits (335), Expect = 2e-30
 Identities = 325/1621 (20%), Positives = 584/1621 (36%), Gaps = 231/1621 (14%)

Query: 628   IQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISI 684
             + W  P     S I+ Y+L  R   +V   K    P    +    GL+ G  YE ++ +I
Sbjct: 13009 VSWKPPADDGGSPITGYLLEKRETQAVNWTKVNRKPIIERTLKATGLQEGTEYEFRVTAI 13068

Query: 685   QQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSW---- 740
              + G  + +              S         + P       V + T SS  +SW    
Sbjct: 13069 NKAGPGKPSD------------ASKAAYARDPQYPPGPPAFPKVYDTTRSSVSLSWGKPA 13116

Query: 741   VSASDTVSGFRVEYELSEEGDEPQYLDLPSTA--TSVNIPDLLPGRKYIVNVYQISEDGE 798
                   + G+ VE + ++  D     +LP     T   +  L+   +Y   VY +++ G 
Sbjct: 13117 YDGGSPIIGYLVEVKRADS-DNWVRCNLPQNLQKTRFEVTGLMEDTQYQFRVYAVNKIGY 13175

Query: 799   QSLILSTSQTTAPDA--------PPDPTVDQVDDTSIVVRWS---RPQAPITGYRIVYSP 847
                   +  +  PD         PP+  +D     ++++R     R   P+ G      P
Sbjct: 13176 ------SDPSDVPDKHYPKDILIPPEGELDADLRKTLILRAGVTMRLYVPVKGRP---PP 13226

Query: 848   SVEGSSTELNLPETAN-SVTLSDLQPGVQ-----------YNITIYAVEENQESTPVVIQ 895
              +  S   +NL +     +  +D    ++           Y +T+      +E T VV  
Sbjct: 13227 KITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKYILTLENSCGKKEYTIVVKV 13286

Query: 896   QETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPGEHG 951
              +T G P + TV         E++     + W PP     S +  Y V            
Sbjct: 13287 LDTPGPPVNVTVK--------EISKDSAYVTWEPPIIDGGSPIINYVVQKRDAERKSWST 13338

Query: 952   QRLPISRNTFAEVTGLSPGVTYYFKVFAVSH---GRESKPLTAQQTTKLDAPT-NLQFVN 1007
                  S+ +F  V  L  G +Y+F+VFA +    G   +   A + ++   P  +L+  +
Sbjct: 13339 VTTECSKTSF-RVANLEEGKSYFFRVFAENEYGIGDPGETRDAVKASQTPGPVVDLKVRS 13397

Query: 1008  ETDSTVLVRWTPPRA----QITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYT 1063
              + S+  + W  P +    +I GY +   LT   + ++     S+ +Y  ++L    EYT
Sbjct: 13398 VSKSSCSIGWKKPHSDGGSRIIGYVVDF-LTEENKWQRVMKSLSL-QYSAKDLTEGKEYT 13455

Query: 1064  VSLVAIKGNQE-SPKATGVFT---TLQPG---SSIPPYNTEVTETT-----IVITWTPAP 1111
               + A   N E +P    V      + P      +P       E +     I I   PAP
Sbjct: 13456 FRVSAENENGEGTPSEITVVARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPIKGKPAP 13515

Query: 1112  RIGFKLGVRP-SQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKV 1170
              + +K G  P +       E ++ + +++V          YTI +      ++  I  KV
Sbjct: 13516 SVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKEGTISIKV 13575

Query: 1171  VTPLSPPTNLHLEANPDTGVLTVSW---ERSTTPDITGYRITTTPTNGQQGNSLEEVVHA 1227
             V     PT            +T+ W   +     +IT Y +    +   +  +    V  
Sbjct: 13576 VGKPGIPTGPIKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDSVNNKWVTCASAVQK 13635

Query: 1228  DQSSCTFDNLSPGLEYNVSV-----YTVKDDKESVPI---SDTIIPEVPQLTDLSFVDIT 1279
                  T   L  G+EY   V     Y V +  +S PI       +P+ P   ++  VD+ 
Sbjct: 13636 TTFRVT--RLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVPDAPPPPNI--VDVR 13691

Query: 1280  DSSIGLRWTP---LNSSTIIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDI 1336
               S+ L WT       S I GY +        +    +     +  + VTGL  G++Y+ 
Sbjct: 13692 HDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTPIRMRDFKVTGLTEGLEYEF 13751

Query: 1337  SVITLINGGESAPTTLTQQTA----VPPPTDLRFTNIGPDTMRVTWAPPP---SIDLTNF 1389
              V+ +   G   P+  ++       + PP      NI  +++ + W  P       LT +
Sbjct: 13752 RVMAINLAGVGKPSLPSEPVVALDPIDPPGKPEVINITRNSVTLIWTEPKYDGGHKLTGY 13811

Query: 1390  LVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVV---------SVSSVYEQHESTP 1440
             +V    + ++  +    ++  + A  +T+L+ G +Y           ++S+  E  E+  
Sbjct: 13812 IVEKRDLPSKSWMKANHVNVPECAFTVTDLVEGGKYEFRIRAKNTAGAISAPSESTETII 13871

Query: 1441  LRGRQK--TGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVP 1498
              +   +  T +  PT  D   I A    V       +I G  +   P+    +  +D  P
Sbjct: 13872 CKDEYEAPTIVLDPTIKDGLTIKAGDTIV---LNAISILGKPL---PKSSWSKAGKDIRP 13925

Query: 1499  HSRNSITLTNLTP-----------GTEYVVSIVALNGREESPLLIGQQSTVSDVPRD--- 1544
                  IT T  +              EY ++     G +   + +    TV DVP     
Sbjct: 13926 SDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFGTKVEHVKV----TVLDVPGPPGP 13981

Query: 1545  LEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATI-------- 1596
             +E+   +     ++W  P            E GG SP++ + +   +++  +        
Sbjct: 13982 VEISNVSAEKATLTWTPPL-----------EDGG-SPIKSYILEKRETSRLLWTVVSEDI 14029

Query: 1597  -------SGLKPGVDYTITVYAVT--GRGDSPASSKPISINYRT-EIDKPSQMQVTDVQD 1646
                    + L  G +Y   V AV   G+G+ P  S+P+ +  R      P + +V++V  
Sbjct: 14030 QSCRHVATKLIQGNEYIFRVSAVNHYGKGE-PVQSEPVKMVDRFGPPGPPEKPEVSNVTK 14088

Query: 1647  NSISVKWL----PSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVS 1702
             N+ +V W        S +TGY V    K      +            + GLQ    Y   
Sbjct: 14089 NTATVSWKRPVDDGGSEITGYHVERREKKSLRWVRAIKTPVSDLRCKVTGLQEGSTYEFR 14148

Query: 1703  VYAQNPSGESQP-------LVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQG----QVS 1751
             V A+N +G   P       L++ A      P     TD    S  +AW  P      +++
Sbjct: 14149 VSAENRAGIGPPSEASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLAWGKPHYDGGLEIT 14208

Query: 1752  RYRVTYSSPEDGIHELFPAPDGEEDTA-ELQGLRPGSEYTVSVVALHDDMESQPLIGTQS 1810
              Y V +    D              T   +  L+   +Y   + A++D    +P +    
Sbjct: 14209 GYVVEHQKVGDEAWIKDTTGTALRITQFVVPDLQTKEKYNFRISAINDAGVGEPAV---- 14264

Query: 1811  TAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDS----- 1865
               IP    ++        L A+     V   G  +R+    K  P  E+    D+     
Sbjct: 14265 --IPDVEIVEREMAPDFELDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKN 14322

Query: 1866  -------SSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTT--LENVSPPRRARVTDA 1916
                     S  +  +    +Y+   + +     +    G V    L+   P    R TD 
Sbjct: 14323 RANIENTESFTLLIIPECNRYDTGKFVMTIENPAGKKSGFVNVRVLDTPGPVLNLRPTDI 14382

Query: 1917  TETTITISWRTKT----ETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKI 1972
             T+ ++T+ W          IT + V+   A  ++    T K    +Y +TGL  G +Y  
Sbjct: 14383 TKDSVTLHWDLPLIDGGSRITNYIVEKREATRKSYSTATTKCHKCTYKVTGLSEGCEYFF 14442

Query: 1973  YLYTLNDNARSSPVV----IDASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGY 2024
              +   N+     P      + AS A   P +L  +  T +++ ++W  P+    ++ITGY
Sbjct: 14443 RVMAENEYGIGEPTETTEPVKASEAPSPPDSLNIMDITKSTVSLAWPKPKHDGGSKITGY 14502

Query: 2025  IIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQ 2084
             +I+ ++ GS     +   +    E  +  L  G EYT  V+A+ +  +S P   R   V+
Sbjct: 14503 VIEAQRKGSDQWTHITTVKG--LECVVRNLTEGEEYTFQVMAVNSAGRSAPRESRPVIVK 14560

Query: 2085  K 2085
             +
Sbjct: 14561 E 14561



 Score =  128 bits (322), Expect = 6e-29
 Identities = 343/1604 (21%), Positives = 574/1604 (35%), Gaps = 260/1604 (16%)

Query: 611   PVEVFITETPSQPNSHPIQWNAPQ---PSHISKYILRWRPKNSVGRWKEATIPGHLNS-- 665
             P ++ I +  S  +S  + W+ P     S ++ Y++  R +     W   +  G + +  
Sbjct: 20673 PAKIRIAD--STKSSITLGWSKPVYDGGSAVTGYVVEIR-QGEEEEWTTVSTKGEVRTTE 20729

Query: 666   YTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATS 725
             Y +  LKPGV Y  ++ ++   G  E    +    +                 S +    
Sbjct: 20730 YVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQAKDILEAPEIDLDVALRTSVIAKAG 20789

Query: 726   ESVTEITASSF----VVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLL 781
             E V  +          V+W      + G    Y + E  D    L +P    +       
Sbjct: 20790 EDVQVLIPFKGRPPPTVTWRKDEKNL-GSDARYSI-ENTDSSSLLTIPQVTRNDT----- 20842

Query: 782   PGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ----AP 837
                KYI+ +     + + S + S      P A     V  V   ++ + W  P     +P
Sbjct: 20843 --GKYILTIENGVGEPKSSTV-SVKVLDTPAACQKLQVKHVSRGTVTLLWDPPLIDGGSP 20899

Query: 838   ITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQE 897
             I  Y I    + + + + ++   ++ S  L DL     +   + A  E     P     E
Sbjct: 20900 IINYVIEKRDATKRTWSVVSHKCSSTSFKLIDLSEKTPFFFRVLAENEIGIGEPC----E 20955

Query: 898   TTGTPRSDTVPSP-RDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPVNLPGEHG- 951
             TT   ++  VP+P RDL   + T   V + WT P+    S +T Y   V+     GE   
Sbjct: 20956 TTEPVKAAEVPAPIRDLSMKDSTKTSVILSWTKPDFDGGSVITEY---VVERKGKGEQTW 21012

Query: 952   QRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDS 1011
                 IS+    EV+ L       F+VFA +    S P+T    T  +    L    E D 
Sbjct: 21013 SHAGISKTCEIEVSQLKEQSVLEFRVFAKNEKGLSDPVTIGPITVKE----LIITPEVDL 21068

Query: 1012  TVLVRWTPPRAQIT---GYRLTVGLTRRGQPRQYNVGPSVS----KYPLRNLQ------P 1058
             + +     P AQ+T   G+ + + L  +G+P+     PS+S      PL+  +       
Sbjct: 21069 SDI-----PGAQVTVRIGHNVHLELPYKGKPK-----PSISWLKDGLPLKESEFVRFSKT 21118

Query: 1059  ASEYTVSLVAIKGNQESPKATGVFT-------------TLQPGSSI--PPYNTEVTETTI 1103
              ++ T+S+   K  +   K T +               TL P S    P    E+   ++
Sbjct: 21119 ENKITLSIKNAK-KEHGGKYTVILDNAVCRIAVPITVITLGPPSKPKGPIRFDEIKADSV 21177

Query: 1104  VITWTPAPRIGFKLGVRPSQGGEAP------REVTSDSGSIVVSG----------LTPGV 1147
             +++W      G         GGE        RE +  +  +V S           L    
Sbjct: 21178 ILSWDVPEDNG---------GGEITCYSIEKRETSQTNWKMVCSSVARTTFKVPNLVKDA 21228

Query: 1148  EYVYTIQVLRDGQERDAPIVNKVVTP-----LSPPTNLHLEANPDTGVLTVSWERSTTP- 1201
             EY + ++   +      P+V+ ++       +  P    +  N  +  ++++W+      
Sbjct: 21229 EYQFRVRA-ENRYGVSQPLVSSIIVAKHQFRIPGPPGKPVIYNVTSDGMSLTWDAPVYDG 21287

Query: 1202  --DITGYRITTTPTNG---QQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKES 1256
               ++TG+ +     N    Q+ N+    +   +   T   L  GL+Y   VY       S
Sbjct: 21288 GSEVTGFHVEKKERNSILWQKVNT--SPISGREYRAT--GLVEGLDYQFRVYAENSAGLS 21343

Query: 1257  VPISDT-----IIPEVPQLTDLSFVDITDSSIGLRWTPL---NSSTIIGYRITVVAAGEG 1308
              P   +     + P  P  T   ++D+T  +I L+W P      S I+GY I      E 
Sbjct: 21344 SPSDPSKFTLAVSPVDPPGTP-DYIDVTRETITLKWNPPLRDGGSKIVGYSIEKRQGNER 21402

Query: 1309  IPIFEDFVDSSVGYYTVTGLEPGIDYDISVI------TLINGGESAPTTLTQQTAVPPPT 1362
               +  +F D S   YTVTGL PG  Y+  +I      T+    +S+   +T+   VPP  
Sbjct: 21403 W-VRCNFTDVSECQYTVTGLSPGDRYEFRIIARNAVGTISPPSQSSGIIMTRDENVPP-- 21459

Query: 1363  DLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNE---EDVAELSISPSDNAVVLTNL 1419
                    GP+                 LV+  PV      +D  E+    +   + +T++
Sbjct: 21460 ---IVEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMN---MEITDV 21513

Query: 1420  LPGTEYVV--------SVSSVYEQHESTPLRGRQKTGLDSPTG-----IDFSDITANSFT 1466
             L  T   V         V +V  ++ S   +   K  +    G     I F++IT    T
Sbjct: 21514 LGSTSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQDTPGKVVGPIRFTNITGEKMT 21573

Query: 1467  VHWIAPR----ATITGYRI-RHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVA 1521
             + W AP     A IT Y I +      +    ED+      S T   L  G EY   + A
Sbjct: 21574 LWWDAPLNDGCAPITHYIIEKRETSRLAWALIEDKC--EAQSYTAIKLINGNEYQFRVSA 21631

Query: 1522  LN----GR--EESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGE 1575
             +N    GR  +  P++   Q TV D P   E    T  S+ ++W  P            E
Sbjct: 21632 VNKFGVGRPLDSDPVVAQIQYTVPDAPGIPEPSNITGNSITLTWARP------------E 21679

Query: 1576  TGGNSPVQEFTV-----------------PGSKSTATISGLKPGVDYTITVYAVTGRGDS 1618
             + G S +Q++ +                 P S++   ++GL  G +Y   V A    G  
Sbjct: 21680 SDGGSEIQQYILERREKKSTRWVKVISKRPISETRFKVTGLTEGNEYEFHVMAENAAGVG 21739

Query: 1619  PASSKPISINYRTEIDKPSQ---MQVTDVQDNSISVKW----LPSSSPVTGYRVTTTPKN 1671
             PAS     I  R  ++ P     ++VTD    ++S++W          + GY +     +
Sbjct: 21740 PASGISRLIKCREPVNPPGPPTVVKVTDTSKTTVSLEWSKPVFDGGMEIIGYIIEMCKAD 21799

Query: 1672  GPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTA-VTNIDRPKGLA 1730
                  K       +T  T+  LQ   EY   V A N +G+      T  +  +DR   L 
Sbjct: 21800 LGDWHKVNAEACVKTRYTVTDLQAGEEYKFRVSAINGAGKGDSCEVTGTIKAVDR---LT 21856

Query: 1731  FTDVDVDS-IKIAWESPQGQVSRYRVTY----------SSPEDGIH---ELFPAPDGEED 1776
               ++D+D+  K       G   R  + Y          S P+  +    ++         
Sbjct: 21857 APELDIDANFKQTHVVRAGASIRLFIAYQGRPTPTAVWSKPDSNLSLRADIHTTDSFSTL 21916

Query: 1777  TAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPP 1836
             T E        +YT++V            +    T  P P  + F  VT  S +  W  P
Sbjct: 21917 TVENCNRNDAGKYTLTVENNSGSKSITFTVKVLDTPGP-PGPITFKDVTRGSATLMWDAP 21975

Query: 1837  NVQLTGYRVRVTPKEKTGPMKE----INLAPDSSSVVVSGLMVATKYEVSVYALKDTLTS 1892
              +   G R+     EK    +     I+         V+ L     Y   V A+ +    
Sbjct: 21976 LLD-GGARIHHYVVEKREASRRSWQVISEKCTRQIFKVNDLAEGVPYYFRVSAVNEYGVG 22034

Query: 1893  RPAQ--GVVTTLENVSPPRRARVTDATETTITISW----RTKTETITGFQVDAVPANGQT 1946
              P +    +   E  +PPRR  V D ++++  ++W          ITG+ ++        
Sbjct: 22035 EPYEMPEPIVATEQPAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSDF 22094

Query: 1947  PIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATT 2006
              ++      + ++T+  L   T+Y+  +   ND   S P    +S  I  P         
Sbjct: 22095 WVEAGHTKQL-TFTVERLVEKTEYEFRVKAKNDAGYSEPREAFSSVIIKEPQ------IE 22147

Query: 2007  PNSLLVSWQPPRARITGYIIKYEKPGSPPREVVP---RPRPGVT 2047
             P + L         IT  +I   K GSP    VP   RP P VT
Sbjct: 22148 PTADLTG-------ITNQLITC-KAGSPFTIDVPISGRPAPKVT 22183



 Score =  124 bits (311), Expect = 1e-27
 Identities = 291/1338 (21%), Positives = 513/1338 (38%), Gaps = 174/1338 (13%)

Query: 780   LLPGRKYI-----VNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRP 834
             ++ G +YI     VN Y I E  E   +++ +    P  P  P V ++   S+ V WSRP
Sbjct: 20533 IIKGNEYIFRVRAVNKYGIGEPLESDSVVAKNAFVTPGPPGIPEVTKITKNSMTVVWSRP 20592

Query: 835   QA----PITGYRIVYSPSVEGSSTEL---NLPETANSVTLSDLQPGVQYNI-TIYAVEEN 886
              A     I+GY +           ++    + +T   VT        QY +  + A  + 
Sbjct: 20593 IADGGSDISGYFLEKRDKKSLGWFKVLKETIRDTRQKVTGLTENSDYQYRVCAVNAAGQG 20652

Query: 887   QESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVI 942
               S P    +        D    P  ++  + T   +T+ W+ P     SAVTGY V++ 
Sbjct: 20653 PFSEP---SEFYKAADPIDPPGPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVVEI- 20708

Query: 943   PVNLPGEHGQRLPIS-----RNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTK- 996
                  GE  +   +S     R T   V+ L PGV YYF+V AV+   + +P+   +  + 
Sbjct: 20709 ---RQGEEEEWTTVSTKGEVRTTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEPVQA 20765

Query: 997   ---LDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQP--------RQYNVG 1045
                L+AP       E D  V +R T   A+  G  + V +  +G+P         + N+G
Sbjct: 20766 KDILEAP-------EIDLDVALR-TSVIAK-AGEDVQVLIPFKGRPPPTVTWRKDEKNLG 20816

Query: 1046  PSVSKYPLRNLQPASEYTVS----------LVAIKGNQESPKATGVFTTL--QPGSSIPP 1093
              S ++Y + N   +S  T+           ++ I+     PK++ V   +   P +    
Sbjct: 20817 -SDARYSIENTDSSSLLTIPQVTRNDTGKYILTIENGVGEPKSSTVSVKVLDTPAACQKL 20875

Query: 1094  YNTEVTETTIVITWTP------APRIGFKLGVRPS---QGGEAPREVTSDSGSIV-VSGL 1143
                 V+  T+ + W P      +P I + +  R +          + +S S  ++ +S  
Sbjct: 20876 QVKHVSRGTVTLLWDPPLIDGGSPIINYVIEKRDATKRTWSVVSHKCSSTSFKLIDLSEK 20935

Query: 1144  TPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDI 1203
             TP    V     +  G+  +     K     +P  +L ++ +  T V+ +SW   T PD 
Sbjct: 20936 TPFFFRVLAENEIGIGEPCETTEPVKAAEVPAPIRDLSMKDSTKTSVI-LSW---TKPDF 20991

Query: 1204  TGYRITTTPTNGQQGNSLEEVVHADQS-SCTFD----NLSPGLEYNVSVYTVKDDKESVP 1258
              G  + T     ++G   +   HA  S +C  +         LE+ V     K   + V 
Sbjct: 20992 DGGSVITEYVVERKGKGEQTWSHAGISKTCEIEVSQLKEQSVLEFRVFAKNEKGLSDPVT 21051

Query: 1259  ISDTIIPEVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGY----RITVVAAGEGIPIFE- 1313
             I    + E+    ++   DI  + + +R    N    + Y    + ++    +G+P+ E 
Sbjct: 21052 IGPITVKELIITPEVDLSDIPGAQVTVR-IGHNVHLELPYKGKPKPSISWLKDGLPLKES 21110

Query: 1314  DFVDSSVGYYTVT------GLEPGIDYDISVITLINGGESAPTTLTQQTAVPPPTDLRFT 1367
             +FV  S     +T        E G  Y + +   +       T +T      P   +RF 
Sbjct: 21111 EFVRFSKTENKITLSIKNAKKEHGGKYTVILDNAVCRIAVPITVITLGPPSKPKGPIRFD 21170

Query: 1368  NIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSI---SPSDNAVVLTNLLPGTE 1424
              I  D++ ++W  P   +    +  YS  K E       +   S +     + NL+   E
Sbjct: 21171 EIKADSVILSWDVPED-NGGGEITCYSIEKRETSQTNWKMVCSSVARTTFKVPNLVKDAE 21229

Query: 1425  YVVSVSSVYEQHESTPL-----RGRQKTGLDSPTGID-FSDITANSFTVHWIAP----RA 1474
             Y   V +      S PL       + +  +  P G     ++T++  ++ W AP     +
Sbjct: 21230 YQFRVRAENRYGVSQPLVSSIIVAKHQFRIPGPPGKPVIYNVTSDGMSLTWDAPVYDGGS 21289

Query: 1475  TITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQ 1534
              +TG+ +     +     + +  P S      T L  G +Y   + A N    S      
Sbjct: 21290 EVTGFHVEKKERNSILWQKVNTSPISGREYRATGLVEGLDYQFRVYAENSAGLSSPSDPS 21349

Query: 1535  QSTVS----DVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYG---ETGGNSPVQEFTV 1587
             + T++    D P   + +  T  ++ + W+ P        + Y      G    V+    
Sbjct: 21350 KFTLAVSPVDPPGTPDYIDVTRETITLKWNPPLRDGGSKIVGYSIEKRQGNERWVRCNFT 21409

Query: 1588  PGSKSTATISGLKPGVDYTITVYAVTGRGD-SPASSKPISINYRTEIDKPSQMQVTDVQD 1646
               S+   T++GL PG  Y   + A    G  SP S     I  R E   P      +  D
Sbjct: 21410 DVSECQYTVTGLSPGDRYEFRIIARNAVGTISPPSQSSGIIMTRDENVPPIVEFGPEYFD 21469

Query: 1647  -------NSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTK----TAGPDQTEMTIEGLQP 1695
                     S+ +K L    PV   RVT   K+G    K      T     T + +     
Sbjct: 21470 GLIIKSGESLRIKALVQGRPVP--RVTWF-KDGVEIEKRMNMEITDVLGSTSLFVRDATR 21526

Query: 1696  TVEYVVSVYAQNPSGESQPLVQTAVTNIDRP----KGLAFTDVDVDSIKIAWESPQGQ-- 1749
                 V +V A+N SG ++  ++  V   D P      + FT++  + + + W++P     
Sbjct: 21527 DHRGVYTVEAKNASGSAKAEIKVKVQ--DTPGKVVGPIRFTNITGEKMTLWWDAPLNDGC 21584

Query: 1750  --VSRYRVTYSSPEDGIHELFPAPDGEEDTAELQG-----LRPGSEYTVSVVALHD---- 1798
               ++ Y +           L       ED  E Q      L  G+EY   V A++     
Sbjct: 21585 APITHYIIEKRETSRLAWALI------EDKCEAQSYTAIKLINGNEYQFRVSAVNKFGVG 21638

Query: 1799  -DMESQPLIGTQSTAIP-APTDLKFTQVTPTSLSAQWTPP----NVQLTGYRVRVTPKEK 1852
               ++S P++      +P AP   + + +T  S++  W  P      ++  Y +    K+ 
Sbjct: 21639 RPLDSDPVVAQIQYTVPDAPGIPEPSNITGNSITLTWARPESDGGSEIQQYILERREKKS 21698

Query: 1853  TGPMKEINLAPDSSS-VVVSGLMVATKYEVSVYALKDTLTSRPAQGV---VTTLENVS-- 1906
             T  +K I+  P S +   V+GL    +YE  V A ++     PA G+   +   E V+  
Sbjct: 21699 TRWVKVISKRPISETRFKVTGLTEGNEYEFHVMA-ENAAGVGPASGISRLIKCREPVNPP 21757

Query: 1907  -PPRRARVTDATETTITISWRTKT----ETITGFQVDAVPANGQTPIQRTIKPDVRS-YT 1960
              PP   +VTD ++TT+++ W          I G+ ++   A+     +   +  V++ YT
Sbjct: 21758 GPPTVVKVTDTSKTTVSLEWSKPVFDGGMEIIGYIIEMCKADLGDWHKVNAEACVKTRYT 21817

Query: 1961  ITGLQPGTDYKIYLYTLN 1978
             +T LQ G +YK  +  +N
Sbjct: 21818 VTDLQAGEEYKFRVSAIN 21835



 Score =  123 bits (309), Expect = 2e-27
 Identities = 310/1432 (21%), Positives = 508/1432 (35%), Gaps = 230/1432 (16%)

Query: 814   PPDPT-VDQVDDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTLS 868
             PP P  +  V      + W+ P     +PI  Y +    +     T ++    +     +
Sbjct: 13978 PPGPVEISNVSAEKATLTWTPPLEDGGSPIKSYILEKRETSRLLWTVVSEDIQSCRHVAT 14037

Query: 869   DLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVE-VTDVKVTIMW 927
              L  G +Y   + AV    +  PV  Q E          P P +   V  VT    T+ W
Sbjct: 14038 KLIQGNEYIFRVSAVNHYGKGEPV--QSEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSW 14095

Query: 928   TPPE----SAVTGYRVDVIPV-NLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSH 982
               P     S +TGY V+     +L      + P+S +   +VTGL  G TY F+V A + 
Sbjct: 14096 KRPVDDGGSEITGYHVERREKKSLRWVRAIKTPVS-DLRCKVTGLQEGSTYEFRVSAENR 14154

Query: 983   GRESKPLTAQQTTKL-DA------PTNLQFVNETDSTVLVRWTPPR----AQITGYRLTV 1031
                  P  A  +  + DA      P+N    + T  +  + W  P      +ITGY +  
Sbjct: 14155 AGIGPPSEASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLAWGKPHYDGGLEITGYVVEH 14214

Query: 1032  GLTRRGQPRQYNVGPS--VSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGS 1089
                      +   G +  ++++ + +LQ   +Y   + AI        A      +    
Sbjct: 14215 QKVGDEAWIKDTTGTALRITQFVVPDLQTKEKYNFRISAINDAGVGEPAVIPDVEIVERE 14274

Query: 1090  SIPPY--NTEVTETTIVITWTPAPRIGFKLGVR-PSQGGEAPREVTSDSGSIVVSG---- 1142
               P +  + E+  T +V       R G  + +  P +G  AP EVT    +I +      
Sbjct: 14275 MAPDFELDAELRRTLVV-------RAGLSIRIFVPIKGRPAP-EVTWTKDNINLKNRANI 14326

Query: 1143  ---------LTPGVEYVYT---IQVLRDGQERDAPIVN-KVVTPLSPPTNLH-LEANPDT 1188
                      + P      T   +  + +   + +  VN +V+    P  NL   +   D+
Sbjct: 14327 ENTESFTLLIIPECNRYDTGKFVMTIENPAGKKSGFVNVRVLDTPGPVLNLRPTDITKDS 14386

Query: 1189  GVLTVSWERSTTPD---ITGYRITTTPTNGQQGNSLEEVVHADQSSCTFD--NLSPGLEY 1243
               +T+ W+         IT Y +       +  ++     H     CT+    LS G EY
Sbjct: 14387 --VTLHWDLPLIDGGSRITNYIVEKREATRKSYSTATTKCH----KCTYKVTGLSEGCEY 14440

Query: 1244  NVSV-----YTVKDDKESV-PISDTIIPEVPQLTDLSFVDITDSSIGLRWTPLN---SST 1294
                V     Y + +  E+  P+  +  P  P    L+ +DIT S++ L W        S 
Sbjct: 14441 FFRVMAENEYGIGEPTETTEPVKASEAPSPPD--SLNIMDITKSTVSLAWPKPKHDGGSK 14498

Query: 1295  IIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLE-------PGIDYDISVITLINGGES 1347
             I GY I     G          D      TV GLE        G +Y   V+ + + G S
Sbjct: 14499 ITGYVIEAQRKGS---------DQWTHITTVKGLECVVRNLTEGEEYTFQVMAVNSAGRS 14549

Query: 1348  APT----TLTQQTAVPPPTDLR-------FTNIGPDT---MRVTWAPPPSIDLTNFLVRY 1393
             AP      + ++  + P  DLR           G +    + V   P P++         
Sbjct: 14550 APRESRPVIVKEQTMLPELDLRGIYQKLVIAKAGDNIKVEIPVLGRPKPTVTW------- 14602

Query: 1394  SPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGL---- 1449
                K  + + + +   +      + +L   E V S S  Y      PL  R   G     
Sbjct: 14603 ---KKGDQILKQTQRVNFETTATSTILNINECVRSDSGPY------PLTARNIVGEVGDV 14653

Query: 1450  ---------DSPTG-IDFSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPRED 1495
                        PTG I F +++++  T  W  P       I+ Y +       S    E 
Sbjct: 14654 ITIQVHDIPGPPTGPIKFDEVSSDFVTFSWDPPENDGGVPISNYVVEMRQTD-STTWVEL 14712

Query: 1496  RVPHSRNSITLTNLTPGTEYVVSIVALN------GREESPLLIGQQSTVSDVPRDLEVVA 1549
                  R +   T LT G EY   + A N      G   + ++      V   P   +V A
Sbjct: 14713 ATTVIRTTYKATRLTTGLEYQFRVKAQNRYGVGPGITSACIVANYPFKVPGPPGTPQVTA 14772

Query: 1550  ATPTSLLISWDAP----AVTVRYYRITYGETGGN--SPVQEFTVPGSKSTATISGLKPGV 1603
              T  S+ ISW  P       +  Y +   E  G     V +  VPG+   +  SGL  G+
Sbjct: 14773 VTKDSMTISWHEPLSDGGSPILGYHVERKERNGILWQTVSKALVPGNIFKS--SGLTDGI 14830

Query: 1604  DYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKW----LPSSSP 1659
              Y   V A    G S  S     +     ID P +    ++  +++++KW          
Sbjct: 14831 AYEFRVIAENMAGKSKPSKPSEPMLALDPIDPPGKPVPLNITRHTVTLKWAKPEYTGGFK 14890

Query: 1660  VTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQ-- 1717
             +T Y V           K   +   + E T+ GL     Y   V A+N +G   P  +  
Sbjct: 14891 ITSYIVEKRDLPNGRWLKANFSNILENEFTVSGLTEDAAYEFRVIAKNAAGAISPPSEPS 14950

Query: 1718  TAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDT 1777
              A+T  D        DV+   IK+  +     + +    +    D      P  +  +D 
Sbjct: 14951 DAITCRD--------DVEAPKIKVDVKFKDTVILKAGEAFRLEADVSGRPPPTMEWSKDG 15002

Query: 1778  AELQGL---------------------RPGSEYTVSVVALHDDMESQPLIGTQSTAIPAP 1816
              EL+G                      R    YT++  A +    ++ +   +    P P
Sbjct: 15003 KELEGTAKLEIKIADFSTNLVNKDSTRRDSGAYTLT--ATNPGGFAKHIFNVKVLDRPGP 15060

Query: 1817  TD--LKFTQVTPTSLSAQWTPP----NVQLTGYRVRVTPKEKTGPMKEINLAPD--SSSV 1868
              +  L  T+VT       W PP      ++  Y   +  K +T  +   N+A +   + +
Sbjct: 15061 PEGPLAVTEVTSEKCVLSWFPPLDDGGAKIDHY---IVQKRETSRLAWTNVASEVQVTKL 15117

Query: 1869  VVSGLMVATKY-----EVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITI 1923
              V+ L+   +Y      V+ Y + + L S P    V       PP+   VT  T+ ++ +
Sbjct: 15118 KVTKLLKGNEYIFRVMAVNKYGVGEPLESEPVL-AVNPYGPPDPPKNPEVTTITKDSMVV 15176

Query: 1924  SW----RTKTETITGFQVDAVPANGQTPIQRTIK--PDVRSYTITGLQPGTDYKIYLYTL 1977
              W          I  + V+     GQ  I+   K   D+R Y ++GL  G +Y+  +   
Sbjct: 15177 CWGHPDSDGGSEIINYIVERRDKAGQRWIKCNKKTLTDLR-YKVSGLTEGHEYEFRIMAE 15235

Query: 1978  NDNARSSP-------VVIDASTAIDAPSNLRFLATTPNSLLVSWQPP----RARITGYII 2026
             N    S+P          D       P N R L T+ +S+ ++W  P     + ITGY++
Sbjct: 15236 NAAGISAPSPTSPFYKACDTVFKPGPPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMV 15295

Query: 2027  KYEKPGSPPREVVPRPRP-GVTEATITGLEPGTEYTIYVIALKNNQKSEPLI 2077
             +   P     ++V  P     T  TITGL    EY I + A+ +    EP +
Sbjct: 15296 EIALPEEDEWQIVTPPAGLKATSYTITGLTENQEYKIRIYAMNSEGLGEPAL 15347



 Score =  123 bits (309), Expect = 2e-27
 Identities = 338/1634 (20%), Positives = 602/1634 (36%), Gaps = 228/1634 (13%)

Query: 613   EVFITETPSQPNSHP-----------IQWNAPQ---PSHISKYILRWRPKNSVGRWKEAT 658
             E ++   P  P   P           +QW  P     S I+ YI+  R     GRW +A+
Sbjct: 17016 ECYVARDPCDPPGTPEPIMVKRNEITLQWTKPVYDGGSMITGYIVEKRDLPD-GRWMKAS 17074

Query: 659   IPGHLNS-YTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTP 717
                 + + +T+ GL     YE ++I+    G         +  S ST      +T +   
Sbjct: 17075 FTNVIETQFTVSGLTEDQRYEFRVIAKNAAGA-------ISKPSDST----GPITAKDEV 17123

Query: 718   FSPLVATSESVTEITASSFVVSWVSASD-------TVSGFRVEYELSEEGD-EPQYLDLP 769
               P ++      +    +   ++   +D       T+   R + E+ E    E +  D  
Sbjct: 17124 ELPRISMDPKFRDTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFK 17183

Query: 770   STATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPT-VDQVDDTSIV 828
             +    V     + G +YI+    ++  G +S  ++      P  P  P  V  V      
Sbjct: 17184 ALLI-VKDAIRIDGGQYILRASNVA--GSKSFPVNVKVLDRPGPPEGPVQVTGVTSEKCS 17240

Query: 829   VRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITI---- 880
             + WS P     + I+ Y +    +   + T +      NS+ ++ L  G +Y   I    
Sbjct: 17241 LTWSPPLQDGGSDISHYVVEKRETSRLAWTVVASEVVTNSLKVTKLLEGNEYVFRIMAVN 17300

Query: 881   -YAVEENQESTPVVIQQETTGTPRSDTVPSP-RDLQFVEVTDVKVTIMWTPPES----AV 934
              Y V E  ES PV+++           +P P + L+   +    +T+ W  P+S     +
Sbjct: 17301 KYGVGEPLESAPVLMKNPFV-------LPGPPKSLEVTNIAKDSMTVCWNRPDSDGGSEI 17353

Query: 935   TGYRV---DVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTA 991
              GY V   D   +     + +R+   R     VTGL+    Y F+V A +     +P  A
Sbjct: 17354 IGYIVEKRDRSGIRWIKCNKRRITDLR---LRVTGLTEDHEYEFRVSAENAAGVGEPSPA 17410

Query: 992   -------QQTTKLDAPTNLQFVNETDSTVLVRWTPP----RAQITGYRLTVGLTRRGQPR 1040
                        K   PTN   V+ T +++ + W  P     ++I GY   V + +  +  
Sbjct: 17411 TVYYKACDPVFKPGPPTNAHIVDTTKNSITLAWGKPIYDGGSEILGY--VVEICKADEEE 17468

Query: 1041  QYNVGPS----VSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNT 1096
                V P     V+++ +  L    EY + + A+       +AT V  T++P   +     
Sbjct: 17469 WQIVTPQTGLRVTRFEISKLTEHQEYKIRVCALN-KVGLGEATSVPGTVKPEDKLEAPEL 17527

Query: 1097  EVTETT---IVITWTPAPRIGFKLGVRPS-------QGGEAPREVTSDSG----SIVVSG 1142
             ++       IV+    + RI      RP+       + GE   +V  + G     + +  
Sbjct: 17528 DLDSELRKGIVVRAGGSARIHIPFKGRPTPEITWSREEGEFTDKVQIEKGVNYTQLSIDN 17587

Query: 1143  LTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHL-EANPDTGVLTVSWERSTTP 1201
                     Y +++      + A +  KV+    PP NL + E   D+  L   WE    P
Sbjct: 17588 CDRNDAGKYILKLENSSGSKSAFVTVKVLDTPGPPQNLAVKEVRKDSAFLV--WE---PP 17642

Query: 1202  DITGYRITTTPTNGQQGNSLEEVVHAD----QSSCTFDNLSPGLEYNVSVYTVKDDKESV 1257
              I G          ++ ++ +   +      ++S   +NL+ G  Y   V    +    V
Sbjct: 17643 IIDGGAKVKNYVIDKRESTRKAYANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFGVGV 17702

Query: 1258  PIS--DTIIPEVPQLTD--LSFVDITDSSIGLRWTPLN---SSTIIGYRITVVAAGEGIP 1310
             P+   D +    P      ++  D++ +S  L W        S ++GY   V    +G  
Sbjct: 17703 PVETVDAVKAAEPPSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLGY--VVEMQPKGTE 17760

Query: 1311  IFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTT---------LTQQTAVPPP 1361
              +    +S V    VTGL  G +Y   V      G+S P           LT Q ++  P
Sbjct: 17761 KWSIVAESKVCNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKLP 17820

Query: 1362  TDLRFTNIGPD---TMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTN 1418
              +      G D    + V   P P+I   +++    P+K       +++  +  + VL +
Sbjct: 17821 FNTYSIQAGEDLKIEIPVIGRPRPNI---SWVKDGEPLK---QTTRVNVEETATSTVL-H 17873

Query: 1419  LLPGTE------YVVSVSSVYEQHESTPLRGRQKTGLDSPTG-IDFSDITANSFTVHWIA 1471
             +  G +       V + +S     E+  +   +K G   P G + F +++A+   + W  
Sbjct: 17874 IKEGNKDDFGKYTVTATNSAGTATENLSVIVLEKPG--PPVGPVRFDEVSADFVVISWEP 17931

Query: 1472  PRAT----ITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREE 1527
             P  T    I+ Y +    +  +          +R +I +T L  GTEY   I A N   +
Sbjct: 17932 PAYTGGCQISNYIVEKR-DTTTTTWHMVSATVARTTIKITKLKTGTEYQFRIFAENRYGK 17990

Query: 1528  SPLLIGQQSTVS------DVPRDLEVVAATPTSLLISWDAP----AVTVRYYRITYGETG 1577
             S  L  +   V         P    V + +   +L+ W  P       +  Y +   E  
Sbjct: 17991 SAPLDSKAVIVQYPFKEPGPPGTPFVTSISKDQMLVQWHEPVNDGGTKIIGYHLEQKEKN 18050

Query: 1578  GNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPS 1637
                 V+    P   +    +GL  G++Y   V A    G    S        R   D P 
Sbjct: 18051 SILWVKLNKTPIQDTKFKTTGLDEGLEYEFKVSAENIVGIGKPSKVSECFVARDPCDPPG 18110

Query: 1638  QMQVTDVQDNSISVKW----LPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGL 1693
             + +   +  N++++KW        S +TGY V           K       +TE T+ GL
Sbjct: 18111 RPEAIVITRNNVTLKWKKPAYDGGSKITGYIVEKKDLPDGRWMKASFTNVLETEFTVSGL 18170

Query: 1694  QPTVEYVVSVYAQNPSGE-SQPLVQT-AVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVS 1751
                  Y   V A+N +G  S+P   + A+T  D        ++D  +  +  +     V 
Sbjct: 18171 VEDQRYEFRVIARNAAGNFSEPSDSSGAITARD--------EIDAPNASLDPKYKDVIVV 18222

Query: 1752  RYRVTYSSPED----GIHELFPAPDGE--EDTAELQGLRPGSEYTVSVV--ALHDD---- 1799
                 T+    D     I ++  + DG+  E+TA    ++   + T  VV   +  D    
Sbjct: 18223 HAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQY 18282

Query: 1800  -MESQPLIGTQSTAI-------PAPTD--LKFTQVTPTSLSAQWTPPNVQLTGYRVR--V 1847
              ++   + GT+S  I       P P +  LK T VT       W PP +Q  G  +   +
Sbjct: 18283 ILKLSNVGGTKSIPITVKVLDRPGPPEGPLKVTGVTAEKCYLAWNPP-LQDGGANISHYI 18341

Query: 1848  TPKEKTGPMK--EINLAPDSSSVVVSGLMVATKY-----EVSVYALKDTLTSRPAQGVVT 1900
               K +T  +   +++    + +  V+ L+   +Y      V+ Y + + L S P      
Sbjct: 18342 IEKRETSRLSWTQVSTEVQALNYKVTKLLPGNEYIFRVMAVNKYGIGEPLESGPVT-ACN 18400

Query: 1901  TLENVSPPRRARVTDATETTITISWRTKTE----TITGFQVDAVPANG--QTPIQRTIKP 1954
               +   PP    V+  T+ ++ ++W    +     I G+ ++     G   T   +    
Sbjct: 18401 PYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDKEGVRWTKCNKKTLT 18460

Query: 1955  DVRSYTITGLQPGTDYKIYLYTLNDNARSSPV-------VIDASTAIDAPSNLRFLATTP 2007
             D+R   +TGL  G  Y+  +   N      P          DA      PSN +   T+ 
Sbjct: 18461 DLR-LRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRACDALYPPGPPSNPKVTDTSR 18519

Query: 2008  NSLLVSWQPP----RARITGYIIKYEKPGSPPREVVPRPRPGV--TEATITGLEPGTEYT 2061
             +S+ ++W  P     A + GY+++  K  +        P  G+   + T+T L+  TEY 
Sbjct: 18520 SSVSLAWSKPIYDGGAPVKGYVVEV-KEAAADEWTTCTPPTGLQGKQFTVTKLKENTEYN 18578

Query: 2062  IYVIALKNNQKSEP 2075
               + A+ +    EP
Sbjct: 18579 FRICAINSEGVGEP 18592



 Score =  123 bits (309), Expect = 2e-27
 Identities = 314/1502 (20%), Positives = 546/1502 (36%), Gaps = 190/1502 (12%)

Query: 619   TPSQPNSHPIQWNAP---QPSHISKYILRWRPKNSVGRWKEATIPGHLNS--YTIKGLKP 673
             T +  +S  + W+ P     + +  Y++  + + +   W   T P  L    +T+  LK 
Sbjct: 18515 TDTSRSSVSLAWSKPIYDGGAPVKGYVVEVK-EAAADEWTTCTPPTGLQGKQFTVTKLKE 18573

Query: 674   GVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITA 733
                Y  ++ +I   G  E        T   + V    +     P   L A    V  + A
Sbjct: 18574 NTEYNFRICAINSEGVGE------PATLPGSVVAQERIE---PPEIELDADLRKVVVLRA 18624

Query: 734   SSFVVSWVSASDTVSGFRVEYELSEEGDEP-----QYLDLPSTATSVNIPDLLPGRKYIV 788
             S+ +  +V    T+ G R E E+  E  E        +++ S+ T + I ++        
Sbjct: 18625 SATLRLFV----TIKG-RPEPEVKWEKAEGILTDRAQIEVTSSFTMLVIDNVTRFDSGRY 18679

Query: 789   NVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ----APITGYRIV 844
             N+   +  G ++  ++     +P AP + T+ +V   S+ + W  P     A IT Y + 
Sbjct: 18680 NLTLENNSGSKTAFVNVRVLDSPSAPVNLTIREVKKDSVTLSWEPPLIDGGAKITNYIVE 18739

Query: 845   YSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRS 904
                +   +   +    T  +  + +LQ G  Y   + A  E     P     ETT   + 
Sbjct: 18740 KRETTRKAYATITNNCTKTTFRIENLQEGCSYYFRVLASNEYGIGLPA----ETTEPVKV 18795

Query: 905   DTVPSPRD-LQFVEVTDVKVTIMWTPPES----AVTGYRVDVIPVNLPGEHGQRLPISRN 959
                P P   +  V+VT    TI W  PES     +TGY V++       E        + 
Sbjct: 18796 SEPPLPPGRVTLVDVTRNTATIKWEKPESDGGSKITGYVVEMQTKG--SEKWSTCTQVKT 18853

Query: 960   TFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWT- 1018
               A ++GL+ G  Y F+V AV+    S P       +L  P   + +    S  L   T 
Sbjct: 18854 LEATISGLTAGEEYVFRVAAVNEKGRSDP------RQLGVPVIARDIEIKPSVELPFHTF 18907

Query: 1019  --PPRAQIT-------GYRLTVGLTRRGQP----RQYNVGPSVSKYPLRNLQPASEYTVS 1065
                 R Q+          + TV   + GQ      + NV  S +   L +++ AS+  V 
Sbjct: 18908 NVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSL-SIKEASKEDVG 18966

Query: 1066  LVAIKGNQESPKATGVFTTL---QPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPS 1122
                +  +  +   T   T +   +PG   P    EV+  +I I+W P    G   G + S
Sbjct: 18967 TYELCVSNSAGSITVPITIIVLDRPGPPGPIRIDEVSCDSITISWNPPEYDG---GCQIS 19023

Query: 1123  QGGEAPREVTSDSGSIV----------VSGLTPGVEYVYTIQVL-RDGQ----ERDAPIV 1167
                   +E TS +  IV          +  LT G EY + +    R G+    E  A + 
Sbjct: 19024 NYIVEKKETTSTTWHIVSQAVARTSIKIVRLTTGSEYQFRVCAENRYGKSSYSESSAVVA 19083

Query: 1168  NKVVTPLSPP-TNLHLEANPDTGVLTVSWERSTTPD---ITGYRITTTPTNGQQGNSLEE 1223
                 +P  PP T   + A   T  + V+W+         + GY +     +    +   +
Sbjct: 19084 EYPFSPPGPPGTPKVVHATKST--MLVTWQVPVNDGGSRVIGYHLEYKERSSILWSKANK 19141

Query: 1224  VVHADQSSCTFDNLSPGLEYNVSVYT--------VKDDKESVPISDTIIPE-VPQLTDLS 1274
             ++ AD +      L  GL Y   VY              E VP  D   P   P++T+  
Sbjct: 19142 ILIAD-TQMKVSGLDEGLMYEYRVYAENIAGIGKCSKSCEPVPARDPCDPPGQPEVTN-- 19198

Query: 1275  FVDITDSSIGLRWTPLN---SSTIIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPG 1331
                IT  S+ L+W+  +    + I GY +      +G  +  ++ +    Y+ VT L   
Sbjct: 19199 ---ITRKSVSLKWSKPHYDGGAKITGYIVERRELPDGRWLKCNYTNIQETYFEVTELTED 19255

Query: 1332  IDYDISVI------TLINGGESAPTTLTQQTAVPPPT--DLRFTNI----GPDTMRVT-- 1377
               Y+  V       ++    ES    + +    PP    D++F ++      + +++   
Sbjct: 19256 QRYEFRVFARNAADSVSEPSESTGPIIVKDDVEPPRVMMDVKFRDVIVVKAGEVLKINAD 19315

Query: 1378  --WAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNL----LPGTEYVVSVSS 1431
                 P P I      +        E+ A   I  +DN  +LT          +YV+++ +
Sbjct: 19316 IAGRPLPVISWAKDGIEI------EERARTEIISTDNHTLLTVKDCIRRDTGQYVLTLKN 19369

Query: 1432  VYEQHE-STPLRGRQKTGLDSPTG-IDFSDITANSFTVHWIAPR----ATITGYRI-RHH 1484
             V      +   +   K G   P G ++ + +TA   ++ W  P+    A I  Y + +  
Sbjct: 19370 VAGTRSVAVNCKVLDKPG--PPAGPLEINGLTAEKCSLSWGRPQEDGGADIDYYIVEKRE 19427

Query: 1485  PEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGR------EESPLLIGQQSTV 1538
               H +    E  +     S  +T L  G EY+  +  +N        E   +      TV
Sbjct: 19428 TSHLAWTICEGEL--QMTSCKVTKLLKGNEYIFRVTGVNKYGVGEPLESVAIKALDPFTV 19485

Query: 1539  SDVPRDLEVVAATPTSLLISWDAP----AVTVRYYRITYGETGGNSPVQEFTVPGSKSTA 1594
                P  LE+ + T  S+ + W  P       +  Y I   E      V+    P      
Sbjct: 19486 PSPPTSLEITSVTKESMTLCWSRPESDGGSEISGYIIERREKNSLRWVRVNKKPVYDLRV 19545

Query: 1595  TISGLKPGVDYTITVYAVTGRGDS-PASSKPISINYRTEI---DKPSQMQVTDVQDNSIS 1650
               +GL+ G +Y   VYA    G S P+ + P+ I     +     PS+ ++ D    +I+
Sbjct: 19546 KSTGLREGCEYEYRVYAENAAGLSLPSETSPL-IRAEDPVFLPSPPSKPKIVDSGKTTIT 19604

Query: 1651  VKWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQ 1706
             + W+       +P+TGY V    K+     KT       TE TI GL    EYV  V + 
Sbjct: 19605 IAWVKPLFDGGAPITGYTVEYK-KSDDTDWKTSIQSLRGTEYTISGLTTGAEYVFRVKSV 19663

Query: 1707  NPSGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRY---------RVTY 1757
             N  G S P   +        +     D+D +  K          +            V +
Sbjct: 19664 NKVGASDPSDSSDPQIAKEREEEPLFDIDSEMRKTLIVKAGASFTMTVPFRGRPVPNVLW 19723

Query: 1758  SSPEDGIHELFPAPDGEEDTA---ELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIP 1814
             S P+  +         +  T+   E        +YT+++  +        ++    T  P
Sbjct: 19724 SKPDTDLRTRAYVDTTDSRTSLTIENANRNDSGKYTLTIQNVLSAASLTLVVKVLDTPGP 19783

Query: 1815  APTDLKFTQVTPTSLSAQWTPP----NVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVV 1870
              PT++    VT  S    W  P       +  Y +      K   +   N   +  S  V
Sbjct: 19784 -PTNITVQDVTKESAVLSWDVPENDGGAPVKNYHIEKREASKKAWVSVTNNC-NRLSYKV 19841

Query: 1871  SGLMVATKYEVSVYALKDTLTSRPA---QGVVTTLENVSPPRRARVTDATETTITISW-- 1925
             + L     Y   V    +     PA   +GV  T E  SPP +  VT  ++ +++++W  
Sbjct: 19842 TNLQEGAIYYFRVSGENEFGVGIPAETKEGVKIT-EKPSPPEKLGVTSISKDSVSLTWLK 19900

Query: 1926  --RTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARS 1983
                     I  + V+A+    +  ++  +      + ++GL+  ++Y   ++  N    S
Sbjct: 19901 PEHDGGSRIVHYVVEALEKGQKNWVKCAVAKSTH-HVVSGLRENSEYFFRVFAENQAGLS 19959

Query: 1984  SP 1985
              P
Sbjct: 19960 DP 19961



 Score =  122 bits (307), Expect = 3e-27
 Identities = 331/1598 (20%), Positives = 562/1598 (35%), Gaps = 189/1598 (11%)

Query: 624   NSHPIQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNS--YTIKGLKPGVVYE 678
             NS  + W  P+    S I +YIL  R K S  RW +      ++   + + GL  G  YE
Sbjct: 21669 NSITLTWARPESDGGSEIQQYILERREKKST-RWVKVISKRPISETRFKVTGLTEGNEYE 21727

Query: 679   GQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVV 738
               +++    G    +           PV          P  P V     VT+ + ++  +
Sbjct: 21728 FHVMAENAAGVGPASGIS-RLIKCREPVNP--------PGPPTVV---KVTDTSKTTVSL 21775

Query: 739   SW----VSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQIS 794
              W          + G+ +E   ++ GD  +        T   + DL  G +Y   V  I+
Sbjct: 21776 EWSKPVFDGGMEIIGYIIEMCKADLGDWHKVNAEACVKTRYTVTDLQAGEEYKFRVSAIN 21835

Query: 795   EDGEQSLILSTSQTTAPD--APPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGS 852
               G+      T    A D    P+  +D     + VVR          Y+   +P+   S
Sbjct: 21836 GAGKGDSCEVTGTIKAVDRLTAPELDIDANFKQTHVVRAGASIRLFIAYQGRPTPTAVWS 21895

Query: 853   STELNLPETANSVTLSDLQPGVQYNIT-------IYAVEENQESTPVVIQQETTGTPRSD 905
               + NL   A+  T          N            VE N  S  +    +   TP   
Sbjct: 21896 KPDSNLSLRADIHTTDSFSTLTVENCNRNDAGKYTLTVENNSGSKSITFTVKVLDTPGP- 21954

Query: 906   TVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPGEHGQRLPISRNTF 961
                 P  + F +VT    T+MW  P     + +  Y V+    +           +R  F
Sbjct: 21955 ----PGPITFKDVTRGSATLMWDAPLLDGGARIHHYVVEKREASRRSWQVISEKCTRQIF 22010

Query: 962   AEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQ----TTKLDAPTNLQFVNETDSTVLVRW 1017
              +V  L+ GV YYF+V AV+     +P    +    T +   P  L  V+ + S+ ++ W
Sbjct: 22011 -KVNDLAEGVPYYFRVSAVNEYGVGEPYEMPEPIVATEQPAPPRRLDVVDTSKSSAVLAW 22069

Query: 1018  TPP----RAQITGYRLTVGLTRRGQPRQYNVGPSVS-KYPLRNLQPASEY---------- 1062
               P     ++ITGY L   + ++G       G +    + +  L   +EY          
Sbjct: 22070 LKPDHDGGSRITGYLLE--MRQKGSDFWVEAGHTKQLTFTVERLVEKTEYEFRVKAKNDA 22127

Query: 1063  -------TVSLVAIKGNQESPKA--TGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRI 1113
                      S V IK  Q  P A  TG+   L    +  P+  +V      I+  PAP++
Sbjct: 22128 GYSEPREAFSSVIIKEPQIEPTADLTGITNQLITCKAGSPFTIDVP-----ISGRPAPKV 22182

Query: 1114  GFKL-GVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVT 1172
              +KL  +R  +        T D  ++ V     G    Y + +      +   +   V+ 
Sbjct: 22183 TWKLEEMRLKETDRVSITTTKDRTTLTVKDSMRGDSGRYFLTLENTAGVKTFSVTVVVIG 22242

Query: 1173  PLSPPTNLHLEANPDTGVLTVSW---ERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQ 1229
                P T     ++       +SW   +     +IT Y +    +       +   V   Q
Sbjct: 22243 RPGPVTGPIEVSSVSAESCVLSWGEPKDGGGTEITNYIVEKRESGTTAWQLVNSSVKRTQ 22302

Query: 1230  SSCTFDNLSPGLEYNVSV-----YTVKDDKESVPI---SDTIIPEVPQLTDLSFVDITDS 1281
                T  +L+  +EY+  V     + V    ES PI      + P  P  T      ++ +
Sbjct: 22303 IKVT--HLTKYMEYSFRVSSENRFGVSKPLESAPIIAEHPFVPPSAP--TRPEVYHVSAN 22358

Query: 1282  SIGLRWTPL---NSSTIIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISV 1338
             ++ +RW        S IIGY +        + + E+ V      Y VTGL  G++Y    
Sbjct: 22359 AMSIRWEEPYHDGGSKIIGYWVEKKERNTILWVKENKVPCLECNYKVTGLVEGLEYQFRT 22418

Query: 1339  ITLINGGES----APTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAPPP---SIDLTNFLV 1391
               L   G S    A   +  Q  V  P     T++   T+ + W+ P       +  +++
Sbjct: 22419 YALNAAGVSKASEASRPIMAQNPVDAPGRPEVTDVTRSTVSLIWSAPAYDGGSKVVGYII 22478

Query: 1392  RYSPVKNEEDVAELSIS---PSDNAVVLTNLLPGTEYVVSVSS------VYEQHEST-PL 1441
                PV    D   L  +    SDN   +T L  G  Y   V +      + +  EST P+
Sbjct: 22479 ERKPVSEVGDGRWLKCNYTIVSDNFFTVTALSEGDTYEFRVLAKNAAGVISKGSESTGPV 22538

Query: 1442  RGRQ-----KTGLDSPTGIDFSDITANSFTVHWIA----PRATITGYRIRHHPEHFSGRP 1492
               R      K  LD+    D   I A S  V   A    P   I   +     +      
Sbjct: 22539 TCRDEYAPPKAELDARLHGDLVTIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVS 22598

Query: 1493  REDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVP---RDLEVVA 1549
              +     +   I   + +   +Y +++   +G +   +++     V D P     L V  
Sbjct: 22599 LQYTGKRATAVIKFCDRSDSGKYTLTVKNASGTKAVSVMV----KVLDSPGPCGKLTVSR 22654

Query: 1550  ATPTSLLISWDAP----AVTVRYYRITYGETGGNSPVQEFTVPGSKSTAT--ISGLKPGV 1603
              T     ++W  P       + +Y +   ET   S +    V G   T +  ++ L    
Sbjct: 22655 VTQEKCTLAWSLPQEDGGAEITHYIVERRET---SRLNWVIVEGECPTLSYVVTRLIKNN 22711

Query: 1604  DYTITVYAVTGRGDS-PASSKPI-SINYRTEIDKPSQMQVTDVQDNSISVKWLPSSS--- 1658
             +Y   V AV   G   P  S+PI + N  T    P   +        I ++W    S   
Sbjct: 22712 EYIFRVRAVNKYGPGVPVESEPIVARNSFTIPSPPGIPEEVGTGKEHIIIQWTKPESDGG 22771

Query: 1659  -PVTGYRVTTTPKNGPGPTK-TKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLV 1716
               ++ Y V    K     T+  K      T + +  L    +Y   V A N +G S+P  
Sbjct: 22772 NEISNYLVDKREKKSLRWTRVNKDYVVYDTRLKVTSLMEGCDYQFRVTAVNAAGNSEPSE 22831

Query: 1717  QTAVTNIDR-------PKGLAFTDVDVDSIKIAWESPQGQVSRYRVTY-----SSPEDGI 1764
              +   +          P      D    SI +AW  P        V Y         D  
Sbjct: 22832 ASNFISCREPSYTPGPPSAPRVVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDTDQW 22891

Query: 1765  HELFPAPDGEEDTAELQGLRPGSEYTVSVVALH---------DDMESQPLIGTQSTAIPA 1815
             + +            +  L+ G +Y+  V A++            E +P+   +   +  
Sbjct: 22892 YRVHTNATIRNTEFTVPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEIPDLEL 22951

Query: 1816  PTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTG---PMKEINLAPDSSSVVVSG 1872
               DLK T       S +     V ++G    V    K G     + I    +S S+++  
Sbjct: 22952 ADDLKKTVTIRAGASLRLM---VSVSGRPPPVITWSKQGIDLASRAIIDTTESYSLLI-- 23006

Query: 1873  LMVATKYEVSVYALKDTLTS--RPAQGVVTTLENVSPPRRARVTDATETTITISWRTKT- 1929
             +    +Y+   Y ++    S  + A  +V   +   P    +V + +  ++TI+W   T 
Sbjct: 23007 VDKVNRYDAGKYTIEAENQSGKKSATVLVKVYDTPGPCPSVKVKEVSRDSVTITWEIPTI 23066

Query: 1930  ---ETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKI-----YLYTLNDNA 1981
                  +  + V+   A  +     T K     Y I+GL  GT Y        +Y + +  
Sbjct: 23067 DGGAPVNNYIVEKREAAMRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYGIGEPC 23126

Query: 1982  RSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPP----RARITGYIIKYEKPGSPPRE 2037
              +S  V+ +   +  P+ L  +  T +++ ++W+ P     +R+TGY+++  K G+    
Sbjct: 23127 ETSDAVLVSEVPL-VPAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGTERWM 23185

Query: 2038  VVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEP 2075
              V   +P V E T+T L  G +Y   + A      SEP
Sbjct: 23186 KVVTLKPTVLEHTVTSLNEGEQYLFRIRAQNEKGVSEP 23223



 Score =  120 bits (301), Expect = 2e-26
 Identities = 286/1368 (20%), Positives = 511/1368 (37%), Gaps = 206/1368 (15%)

Query: 866   TLSDLQPGVQYNITIYAVEENQEST-PVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVT 924
             T++ L  G +Y   + A  EN+  T P    +      + D    P   +  +V+  ++T
Sbjct: 11859 TVTRLIEGNEYIFRVRA--ENKIGTGPPTESKPVIAKTKYDKPGRPDPPEVTKVSKEEMT 11916

Query: 925   IMWTPPE----SAVTGYRVDVIPVNLPGEHGQR-LPISRNTFAE----VTGLSPGVTYYF 975
             ++W PPE     ++TGY ++        +H  R +P++++   E    V  L P   Y F
Sbjct: 11917 VVWNPPEYDGGKSITGYFLEK-----KEKHSTRWVPVNKSAIPERRMKVQNLLPDHEYQF 11971

Query: 976   KVFAVSH------GRESKPLTAQQTTKLDAP-TNLQFVNETDSTVLVRWTPP----RAQI 1024
             +V A +          S+P+ A+   +   P TN + V+ T  ++ + W  P     A I
Sbjct: 11972 RVKAENEIGIGEPSLPSRPVVAKDPIEPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAPI 12031

Query: 1025  TGY------RLTVGLTRRGQPRQYNVGPSVSK-YPLRNLQPASEYTVSL-----VAIKGN 1072
              GY      ++       G  R       V K + + +L    EY   +     V I   
Sbjct: 12032 IGYVVEMRPKIADASPDEGWKRCNAAAQLVRKEFTVTSLDENQEYEFRVCAQNQVGIGRP 12091

Query: 1073  QESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWT-------------PAPRIGFKLGV 1119
              E  +A      L+P    P  + + +   +VI                PAP++ ++   
Sbjct: 12092 AELKEAIKPKEILEP----PEIDLDASMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVG 12147

Query: 1120  RPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTN 1179
               +   +   ++      +V+   T      Y++ ++    E+   +  +V+    P ++
Sbjct: 12148 IDNVVRKGQVDLVDTMAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFVNVRVLDTPGPVSD 12207

Query: 1180  LHLEANPDTGVLTVSW---ERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDN 1236
             L +     T    VSW   E      +T Y +     + +  +++   V   ++S    N
Sbjct: 12208 LKVSDVTKTSC-HVSWAPPENDGGSQVTHYIVEKREADRKTWSTVTPEVK--KTSFHVTN 12264

Query: 1237  LSPGLEYNVSVYTVKDDKESVPI--------SDTII-PEVPQLTDLSFVDITDSSIGLRW 1287
             L PG EY   V  V +    VP         SD +  P+ P+   L   ++T +S  L W
Sbjct: 12265 LVPGNEYYFRVTAVNEYGPGVPTDVPKPVLASDPLSEPDPPR--KLEVTEMTKNSATLAW 12322

Query: 1288  TPL---NSSTIIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLING 1344
              P      + I GY  +     +    + ++         VTGL+ G  Y   V      
Sbjct: 12323 LPPLRDGGAKIDGYITSYREEEQPADRWTEYSVVKDLSLVVTGLKEGKKYKFRVAARNAV 12382

Query: 1345  GESAPTTL-----TQQTAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVK-- 1397
             G S P         ++  +PP        + P+ + +       I+   +   +   K  
Sbjct: 12383 GVSLPREAEGVYEAKEQLLPPKI------LMPEQITIKAGKKLRIEAHVYGKPHPTCKWK 12436

Query: 1398  -NEEDV---AELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSP- 1452
               E++V   + L++  +D++ +L       +     S   E    T  +  +   +D+P 
Sbjct: 12437 KGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPG 12496

Query: 1453  ---TGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPH----SRNSIT 1505
                   D SDI A++ ++ W  P     G  I ++        R D V      ++ S  
Sbjct: 12497 PPQPPFDISDIDADACSLSWHIPLED-GGSNITNYIVEKCDVSRGDWVTALASVTKTSCR 12555

Query: 1506  LTNLTPGTEYVVSIVALN--GREE---SPLLIGQ-QSTVSDVPRDLEVVAATPTSLLISW 1559
             +  L PG EY+  + A N  G  E   SP ++ Q    V   P++  V       + ++W
Sbjct: 12556 VGKLIPGQEYIFRVRAENRFGISEPLTSPKMVAQFPFGVPSEPKNARVTKVNKDCIFVAW 12615

Query: 1560  DAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATI----------------SGLKPGV 1603
             D P            ++ G SP+  + +   +  + +                +GL  G+
Sbjct: 12616 DRP------------DSDGGSPIIGYLIERKERNSLLWVKANDTLVRSTEYPCAGLVEGL 12663

Query: 1604  DYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWL----PSSSP 1659
             +Y+  +YA+   G SP S     +  R  +D P + +V DV  +++S+ W        S 
Sbjct: 12664 EYSFRIYALNKAGSSPPSKPTEYVTARMPVDPPGKPEVIDVTKSTVSLIWARPKHDGGSK 12723

Query: 1660  VTGYRVTTTPKNGPGPTKTKTAGPD--QTEMTIEGLQPTVEYVVSVYAQN------PSGE 1711
             + GY V      G    +  TA     Q E T  GL+   +Y     A+       PS  
Sbjct: 12724 IIGYFVEACKLPGDKWVRCNTAPHQIPQEEYTATGLEEKAQYQFRAIARTAVNISPPSEP 12783

Query: 1712  SQP---LVQTAVTNIDRPKGL-------AFTDVDVDSIKIAWESPQGQVS-RYRVTYSSP 1760
             S P   L +     ID    +       A T+V +D+    +  P   VS +   T   P
Sbjct: 12784 SDPVTILAENVPPRIDLSVAMKSLLTVKAGTNVCLDA--TVFGKPMPTVSWKKDGTLLKP 12841

Query: 1761  EDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPA-PTDL 1819
              +GI     A      T EL  +        ++ A +        I  +    P  P  +
Sbjct: 12842 AEGIK---MAMQRNLCTLELFSVNRKDSGDYTITAENSSGSKSATIKLKVLDKPGPPASV 12898

Query: 1820  KFTQVTPTSLSAQWTPP----NVQLTGYRVRVTPKEKTGP-MKEINLAPDSSSVVVSGLM 1874
             K  ++        W PP      ++T Y   V  +E + P   +++     +S  V  L+
Sbjct: 12899 KINKMYSDRAMLSWEPPLEDGGSEITNY--IVDKRETSRPNWAQVSATVPITSCSVEKLI 12956

Query: 1875  VATKYEVSV-----YALKDTLTSRPAQGVVTTLENVSPPRRAR---VTDATETTITISWR 1926
                +Y+  +     Y + D + + PA           PP R     +++ T+  +T+SW+
Sbjct: 12957 EGHEYQFRICAENKYGVGDPVFTEPA----IAKNPYDPPGRCDPPVISNITKDHMTVSWK 13012

Query: 1927  TKTE----TITGFQVDAVPANGQTPIQRTIKPDV-RSYTITGLQPGTDYKIYLYTLNDNA 1981
                +     ITG+ ++          +   KP + R+   TGLQ GT+Y+  +  +N   
Sbjct: 13013 PPADDGGSPITGYLLEKRETQAVNWTKVNRKPIIERTLKATGLQEGTEYEFRVTAINKAG 13072

Query: 1982  RSSPVVIDASTAIDA---------PSNLRFLATTPNSLLVSWQPPR----ARITGYIIKY 2028
                P   DAS A  A         P+  +   TT +S+ +SW  P     + I GY+++ 
Sbjct: 13073 PGKP--SDASKAAYARDPQYPPGPPAFPKVYDTTRSSVSLSWGKPAYDGGSPIIGYLVEV 13130

Query: 2029  EKPGSPPREVVPRPRP-GVTEATITGLEPGTEYTIYVIALKNNQKSEP 2075
             ++  S        P+    T   +TGL   T+Y   V A+     S+P
Sbjct: 13131 KRADSDNWVRCNLPQNLQKTRFEVTGLMEDTQYQFRVYAVNKIGYSDP 13178



 Score =  120 bits (301), Expect = 2e-26
 Identities = 304/1512 (20%), Positives = 534/1512 (35%), Gaps = 204/1512 (13%)

Query: 718   FSPLVATSESVTEITASSFVVSW----VSASDTVSGFRVEYELSEEGDEPQYLDLPSTA- 772
             F P   T+  + + T +S  ++W          + G+ VE  + +  +E   +  P T  
Sbjct: 17421 FKPGPPTNAHIVDTTKNSITLAWGKPIYDGGSEILGYVVE--ICKADEEEWQIVTPQTGL 17478

Query: 773   --TSVNIPDLLPGRKYIVNVYQISEDG--EQSLILSTSQTTAPDAPPDPTVDQVDDTSIV 828
               T   I  L   ++Y + V  +++ G  E + +  T +       P+  +D      IV
Sbjct: 17479 RVTRFEISKLTEHQEYKIRVCALNKVGLGEATSVPGTVKPEDKLEAPELDLDSELRKGIV 17538

Query: 829   VRW---SRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYN-ITIYAVE 884
             VR    +R   P  G     +P +  S  E    +         ++ GV Y  ++I   +
Sbjct: 17539 VRAGGSARIHIPFKGRP---TPEITWSREEGEFTDKVQ------IEKGVNYTQLSIDNCD 17589

Query: 885   ENQESTPVVIQQETTGTPRS-------DTVPSPRDLQFVEVTDVKVTIMWTPP----ESA 933
              N     ++  + ++G+  +       DT   P++L   EV      ++W PP     + 
Sbjct: 17590 RNDAGKYILKLENSSGSKSAFVTVKVLDTPGPPQNLAVKEVRKDSAFLVWEPPIIDGGAK 17649

Query: 934   VTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQ 993
             V  Y +D                S+ +F +V  L+ G  YYF+V A +      P+    
Sbjct: 17650 VKNYVIDKRESTRKAYANVSSKCSKTSF-KVENLTEGAIYYFRVMAENEFGVGVPVETVD 17708

Query: 994   TTKLDAPTN------LQFVNETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYN 1043
               K   P +      L  V++T ++++  W  P     +++ GY   V +  +G  +   
Sbjct: 17709 AVKAAEPPSPPGKVTLTDVSQTSASLM--WEKPEHDGGSRVLGY--VVEMQPKGTEKWSI 17764

Query: 1044  VGPS-VSKYPLRNLQPASEYTVSLVAIKGNQES-PKATGVFT-----TLQPGSSIPPYNT 1096
             V  S V    +  L    EY   + A     +S P+  GV       T+QP   +P +NT
Sbjct: 17765 VAESKVCNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKLP-FNT 17823

Query: 1097  ------EVTETTIVITWTPAPRIGF-KLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEY 1149
                   E  +  I +   P P I + K G    Q      E T+ S  + +         
Sbjct: 17824 YSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFG 17883

Query: 1150  VYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTP---DITGY 1206
              YT+            +   V+    PP             + +SWE         I+ Y
Sbjct: 17884 KYTVTATNSAGTATENLSVIVLEKPGPPVGPVRFDEVSADFVVISWEPPAYTGGCQISNY 17943

Query: 1207  RITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTII-- 1264
              +    T     + +   V   +++     L  G EY   ++      +S P+    +  
Sbjct: 17944 IVEKRDTTTTTWHMVSATVA--RTTIKITKLKTGTEYQFRIFAENRYGKSAPLDSKAVIV 18001

Query: 1265  ---------PEVPQLTDLSFVDITDSSIGLRW-TPLNS--STIIGYRITVVAAGEGIPIF 1312
                      P  P +T +S        + ++W  P+N   + IIGY +        + + 
Sbjct: 18002 QYPFKEPGPPGTPFVTSIS-----KDQMLVQWHEPVNDGGTKIIGYHLEQKEKNSILWVK 18056

Query: 1313  EDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQ----QTAVPPPTDLRFTN 1368
              +        +  TGL+ G++Y+  V      G   P+ +++    +    PP       
Sbjct: 18057 LNKTPIQDTKFKTTGLDEGLEYEFKVSAENIVGIGKPSKVSECFVARDPCDPPGRPEAIV 18116

Query: 1369  IGPDTMRVTWAPPP---SIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEY 1425
             I  + + + W  P       +T ++V     K+  D   +  S        TN+L  TE+
Sbjct: 18117 ITRNNVTLKWKKPAYDGGSKITGYIVEK---KDLPDGRWMKAS-------FTNVLE-TEF 18165

Query: 1426  VVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITG-YR---I 1481
              VS   V +Q     +  R   G  S        ITA        AP A++   Y+   +
Sbjct: 18166 TVS-GLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARD---EIDAPNASLDPKYKDVIV 18221

Query: 1482  RHHPEHF------SGRPREDRV--------------PHSRNSITLTNL-------TPGTE 1514
              H  E F       G+P  D V                 +++I  T L       T G +
Sbjct: 18222 VHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQ 18281

Query: 1515  YVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAP----AVTVRYYR 1570
             Y++ +  + G +  P+ +            L+V   T     ++W+ P       + +Y 
Sbjct: 18282 YILKLSNVGGTKSIPITVKVLDRPGPPEGPLKVTGVTAEKCYLAWNPPLQDGGANISHYI 18341

Query: 1571  ITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRG-DSPASSKPISI-N 1628
             I   ET   S  Q  T   + +   ++ L PG +Y   V AV   G   P  S P++  N
Sbjct: 18342 IEKRETSRLSWTQVSTEVQALNYK-VTKLLPGNEYIFRVMAVNKYGIGEPLESGPVTACN 18400

Query: 1629  YRTEIDKPSQMQVTDVQDNSISVKWL----PSSSPVTGYRVTTTPKNGPGPTKTKTAGPD 1684
                    PS  +V+ +  +S+ V W        + + GY +    K G   TK       
Sbjct: 18401 PYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDKEGVRWTKCNKKTLT 18460

Query: 1685  QTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQT-------AVTNIDRPKGLAFTDVDVD 1737
                + + GL     Y   V A+N +G  +P   +       A+     P     TD    
Sbjct: 18461 DLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRACDALYPPGPPSNPKVTDTSRS 18520

Query: 1738  SIKIAWESP----QGQVSRYRVTYSSPEDGIHELFPAPDGEEDTA-ELQGLRPGSEYTVS 1792
             S+ +AW  P       V  Y V               P G +     +  L+  +EY   
Sbjct: 18521 SVSLAWSKPIYDGGAPVKGYVVEVKEAAADEWTTCTPPTGLQGKQFTVTKLKENTEYNFR 18580

Query: 1793  VVALHDDMESQPL-----IGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRV 1847
             + A++ +   +P      +  Q    P   +L         L A  T         R+ V
Sbjct: 18581 ICAINSEGVGEPATLPGSVVAQERIEPPEIELDADLRKVVVLRASAT--------LRLFV 18632

Query: 1848  TPKEKTGPM----KEINLAPDSSSVVVSGLMV------ATKYEVSVY--ALKDTLTSRPA 1895
             T K +  P     K   +  D + + V+           T+++   Y   L++   S+ A
Sbjct: 18633 TIKGRPEPEVKWEKAEGILTDRAQIEVTSSFTMLVIDNVTRFDSGRYNLTLENNSGSKTA 18692

Query: 1896  QGVVTTLENVSPPRRARVTDATETTITISWRTKT----ETITGFQVDAVPANGQTPIQRT 1951
                V  L++ S P    + +  + ++T+SW          IT + V+      +     T
Sbjct: 18693 FVNVRVLDSPSAPVNLTIREVKKDSVTLSWEPPLIDGGAKITNYIVEKRETTRKAYATIT 18752

Query: 1952  IKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAP----SNLRFLATTP 2007
                   ++ I  LQ G  Y   +   N+     P        +  P      +  +  T 
Sbjct: 18753 NNCTKTTFRIENLQEGCSYYFRVLASNEYGIGLPAETTEPVKVSEPPLPPGRVTLVDVTR 18812

Query: 2008  NSLLVSWQPPRA----RITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIY 2063
             N+  + W+ P +    +ITGY+++ +  GS       + +    EATI+GL  G EY   
Sbjct: 18813 NTATIKWEKPESDGGSKITGYVVEMQTKGSEKWSTCTQVK--TLEATISGLTAGEEYVFR 18870

Query: 2064  VIALKNNQKSEP 2075
             V A+    +S+P
Sbjct: 18871 VAAVNEKGRSDP 18882



 Score =  119 bits (298), Expect = 4e-26
 Identities = 329/1550 (21%), Positives = 553/1550 (35%), Gaps = 222/1550 (14%)

Query: 601   PLQTYPSSSGPVEVFITETPSQPN-------SHPIQWNAPQ---PSHISKYILRWRPKNS 650
             P +T P       VF+   PS+P        +  I W  P     + I+ Y + ++  + 
Sbjct: 19571 PSETSPLIRAEDPVFLPSPPSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEYKKSDD 19630

Query: 651   VGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNT 710
                WK +        YTI GL  G  Y  ++ S+ + G  +        + +S P  +  
Sbjct: 19631 TD-WKTSIQSLRGTEYTISGLTTGAEYVFRVKSVNKVGASD-------PSDSSDPQIAKE 19682

Query: 711   VTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVS--GFRVEYELSEEGDEP----Q 764
                E     PL       +E+  +  V +  S + TV   G  V   L  + D       
Sbjct: 19683 REEE-----PLFDID---SEMRKTLIVKAGASFTMTVPFRGRPVPNVLWSKPDTDLRTRA 19734

Query: 765   YLDLPSTATSVNIPDLL--PGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQV 822
             Y+D   + TS+ I +       KY + +  +      +L++    T  P  P + TV  V
Sbjct: 19735 YVDTTDSRTSLTIENANRNDSGKYTLTIQNVLSAASLTLVVKVLDTPGP--PTNITVQDV 19792

Query: 823   DDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNI 878
                S V+ W  P+    AP+  Y I    + + +   +       S  +++LQ G  Y  
Sbjct: 19793 TKESAVLSWDVPENDGGAPVKNYHIEKREASKKAWVSVTNNCNRLSYKVTNLQEGAIYYF 19852

Query: 879   TIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAV 934
              +    E     P   ++   G   ++    P  L    ++   V++ W  PE    S +
Sbjct: 19853 RVSGENEFGVGIPAETKE---GVKITEKPSPPEKLGVTSISKDSVSLTWLKPEHDGGSRI 19909

Query: 935   TGYRVDVIPVNLPGEHGQR----LPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKP-- 988
               Y V+ +      E GQ+      ++++T   V+GL     Y+F+VFA +    S P  
Sbjct: 19910 VHYVVEAL------EKGQKNWVKCAVAKSTHHVVSGLRENSEYFFRVFAENQAGLSDPRE 19963

Query: 989   -LTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPS 1047
              L      +   P  +   N    TV VR         G  L V +   G+P    V  S
Sbjct: 19964 LLLPVLIKEQLEPPEIDMKNFPSHTVYVR--------AGSNLKVDIPISGKPLP-KVTLS 20014

Query: 1048  VSKYPLR-NLQPASEYTV---------SLVAIKGNQESPKATGVFTTL---------QPG 1088
                 PL+  ++  +E T          S+ A  G  E   A    TT          +PG
Sbjct: 20015 RDGVPLKATMRFNTEITAENLTINLKESVTADAGRYEITAANSSGTTKAFINIVVLDRPG 20074

Query: 1089  SSI-PPYNTEVTETTIVITWTPAPRIG-------FKLGVRPSQGGEAPREVTSDSGSIVV 1140
                 P   +++TE ++ + W P    G         L    S         T     + V
Sbjct: 20075 PPTGPVVISDITEESVTLKWEPPKYDGGSQVTNYILLKRETSTAVWTEVSATVARTMMKV 20134

Query: 1141  SGLTPGVEYVYTIQV-----LRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSW 1195
               LT G EY + I+      + D  +     V    T   PP+   +  N     +TV W
Sbjct: 20135 MKLTTGEEYQFRIKAENRFGISDHIDSACVTVKLPYTTPGPPSTPWV-TNVTRESITVGW 20193

Query: 1196  ERSTT---PDITGYRITTTPTNG---QQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYT 1249
                 +     + GY +     N    Q+ N L  V+       T   +S GL Y   VY 
Sbjct: 20194 HEPVSNGGSAVVGYHLEMKDRNSILWQKANKL--VIRTTHFKVT--TISAGLIYEFRVYA 20249

Query: 1250  V------KDDKESVPISDTIIPEVPQLTDLSFVDITDSSIGLRWTPL---NSSTIIGYRI 1300
                    K    S P+      E P+  ++   DI+ +S+ L W        S I GY +
Sbjct: 20250 ENAAGVGKPSHPSEPVLAIDACEPPR--NVRITDISKNSVSLSWQQPAFDGGSKITGYIV 20307

Query: 1301  TVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISV------------------ITLI 1342
                   +G      F + +   + ++GL     Y+  V                  IT I
Sbjct: 20308 ERRDLPDGRWTKASFTNVTETQFIISGLTQNSQYEFRVFARNAVGSISNPSEVVGPITCI 20367

Query: 1343  N--GGE--SAPTTLTQQTAVPPPTD--LRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPV 1396
             +  GG     P   T+       T   LR    G     + W        TN LV    V
Sbjct: 20368 DSYGGPVIDLPLEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALV---CV 20424

Query: 1397  KNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTG-I 1455
             +N  D+A + I  +D        L    Y + + +      +T +R +       P G I
Sbjct: 20425 ENTTDLASILIKDADR-------LNSGCYELKLRNAMGSASAT-IRVQILDKPGPPGGPI 20476

Query: 1456  DFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRNS-------ITLTN 1508
             +F  +TA   T+ W  P A   G +I H   +   +    RV  S  S       IT T 
Sbjct: 20477 EFKTVTAEKITLLW-RPPADDGGAKITH---YIVEKRETSRVVWSMVSEHLEECIITTTK 20532

Query: 1509  LTPGTEYVVSIVALNGRE-----ESPLLIGQQSTVSDVPRDL-EVVAATPTSLLISWDAP 1562
             +  G EY+  + A+N        ES  ++ + + V+  P  + EV   T  S+ + W  P
Sbjct: 20533 IIKGNEYIFRVRAVNKYGIGEPLESDSVVAKNAFVTPGPPGIPEVTKITKNSMTVVWSRP 20592

Query: 1563  A------VTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRG 1616
                    ++  +      ++ G   V + T+  ++   T  GL    DY   V AV   G
Sbjct: 20593 IADGGSDISGYFLEKRDKKSLGWFKVLKETIRDTRQKVT--GLTENSDYQYRVCAVNAAG 20650

Query: 1617  DSPASSKPISINYRTEID---KPSQMQVTDVQDNSISVKW----LPSSSPVTGYRVTTTP 1669
               P S           ID    P+++++ D   +SI++ W        S VTGY V    
Sbjct: 20651 QGPFSEPSEFYKAADPIDPPGPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVVEIRQ 20710

Query: 1670  KNGPGPTKTKTAGPDQ-TEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKG 1728
                   T   T G  + TE  +  L+P V Y   V A N +G+ +P+       +     
Sbjct: 20711 GEEEEWTTVSTKGEVRTTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMN--EPVQAKDI 20768

Query: 1729  LAFTDVDVD-SIKIAWESPQGQVSRYRVTYSS--PEDGIHELFPAPDGEEDTAELQGLRP 1785
             L   ++D+D +++ +  +  G+  +  + +    P            G +    ++    
Sbjct: 20769 LEAPEIDLDVALRTSVIAKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARYSIENTDS 20828

Query: 1786  GSEYTVSVVALHDDME---------SQPLIGTQSTAI----PAPTDLKFTQVTPTSLSAQ 1832
              S  T+  V  +D  +          +P   T S  +     A   L+   V+  +++  
Sbjct: 20829 SSLLTIPQVTRNDTGKYILTIENGVGEPKSSTVSVKVLDTPAACQKLQVKHVSRGTVTLL 20888

Query: 1833  WTPPNVQLTGYRVRVTPKEKTGPMKEINLAP---DSSSVVVSGLMVATKYEVSVYALKDT 1889
             W PP +      +    +++    +  ++      S+S  +  L   T +   V A  + 
Sbjct: 20889 WDPPLIDGGSPIINYVIEKRDATKRTWSVVSHKCSSTSFKLIDLSEKTPFFFRVLAENEI 20948

Query: 1890  LTSRPAQGV--VTTLENVSPPRRARVTDATETTITISWRTKTE-----TITGFQVDAVPA 1942
                 P +    V   E  +P R   + D+T+T++ +SW TK +      IT + V+    
Sbjct: 20949 GIGEPCETTEPVKAAEVPAPIRDLSMKDSTKTSVILSW-TKPDFDGGSVITEYVVERKGK 21007

Query: 1943  NGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDAST 1992
               QT     I        ++ L+  +  +  ++  N+   S PV I   T
Sbjct: 21008 GEQTWSHAGISKTC-EIEVSQLKEQSVLEFRVFAKNEKGLSDPVTIGPIT 21056



 Score =  118 bits (296), Expect = 6e-26
 Identities = 330/1625 (20%), Positives = 588/1625 (36%), Gaps = 230/1625 (14%)

Query: 611   PVEVFITETPSQPNSHPIQWNAP---QPSHISKYILRWRPKNSVGRWKEATIPGHLNSYT 667
             PV V + E     +S  + W  P     S I  Y+++ R       W   T      S+ 
Sbjct: 13293 PVNVTVKEISK--DSAYVTWEPPIIDGGSPIINYVVQKRDAERKS-WSTVTTECSKTSFR 13349

Query: 668   IKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSES 727
             +  L+ G  Y  ++ +  +YG  +               T + V    TP  P+V     
Sbjct: 13350 VANLEEGKSYFFRVFAENEYGIGDPGE------------TRDAVKASQTP-GPVVDLK-- 13394

Query: 728   VTEITASSFVVSWVS----ASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPG 783
             V  ++ SS  + W          + G+ V++ L+EE    + +   S +   +  DL  G
Sbjct: 13395 VRSVSKSSCSIGWKKPHSDGGSRIIGYVVDF-LTEENKWQRVMK--SLSLQYSAKDLTEG 13451

Query: 784   RKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWS---RPQAPITG 840
             ++Y   V   +E+GE +    T         PD  +  + D   + + +   R + PI G
Sbjct: 13452 KEYTFRVSAENENGEGTPSEITVVARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPIKG 13511

Query: 841   YRIVYSPSVE--------GSSTELNLPETANSVTLS--DLQPGV--QYNITIYAVEENQE 888
                  +PSV          + T +++  +A + TL   D Q     +Y IT+  V   +E
Sbjct: 13512 KP---APSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKE 13568

Query: 889   STPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPV 944
              T   I  +  G P   T P    ++F EVT   +T+ W PP+    S +T Y ++    
Sbjct: 13569 GT---ISIKVVGKPGIPTGP----IKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRD- 13620

Query: 945   NLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKV-----FAVSHGRESKPLTAQQTTKL-D 998
             ++  +        + T   VT L  G+ Y F+V     + V  G +S+P+ A+    + D
Sbjct: 13621 SVNNKWVTCASAVQKTTFRVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVPD 13680

Query: 999   APTNLQFVNETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGP-SVSKYPL 1053
             AP     V+    +V + WT P+    + ITGY L          ++ N  P  +  + +
Sbjct: 13681 APPPPNIVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTPIRMRDFKV 13740

Query: 1054  RNLQPASEYTVSLVAI------KGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITW 1107
               L    EY   ++AI      K +  S     +     PG    P    +T  ++ + W
Sbjct: 13741 TGLTEGLEYEFRVMAINLAGVGKPSLPSEPVVALDPIDPPGK---PEVINITRNSVTLIW 13797

Query: 1108  T-PAPRIGFKL-------GVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDG 1159
             T P    G KL          PS+       V     +  V+ L  G +Y + I+     
Sbjct: 13798 TEPKYDGGHKLTGYIVEKRDLPSKSWMKANHVNVPECAFTVTDLVEGGKYEFRIRAKNTA 13857

Query: 1160  QERDAPIVN----------KVVTPLSPPT---NLHLEANPDTGVLTV-----------SW 1195
                 AP  +          +  T +  PT    L ++A  DT VL             SW
Sbjct: 13858 GAISAPSESTETIICKDEYEAPTIVLDPTIKDGLTIKAG-DTIVLNAISILGKPLPKSSW 13916

Query: 1196  ERS----TTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVK 1251
              ++       DIT  +IT+TPT+     +++     D    T    +P        +  K
Sbjct: 13917 SKAGKDIRPSDIT--QITSTPTSSML--TIKYATRKDAGEYTITATNP--------FGTK 13964

Query: 1252  DDKESVPISDTIIPEVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGEGIPI 1311
              +   V + D  +P  P   ++S  +++     L WTP         +  ++   E   +
Sbjct: 13965 VEHVKVTVLD--VPGPPGPVEIS--NVSAEKATLTWTPPLEDGGSPIKSYILEKRETSRL 14020

Query: 1312  FEDFVDSSVG--YYTVTGLEPGIDYDISVITLINGG-----ESAPTTLTQQTAVP-PPTD 1363
                 V   +    +  T L  G +Y   V  + + G     +S P  +  +   P PP  
Sbjct: 14021 LWTVVSEDIQSCRHVATKLIQGNEYIFRVSAVNHYGKGEPVQSEPVKMVDRFGPPGPPEK 14080

Query: 1364  LRFTNIGPDTMRVTWAPP---PSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLL 1420
                +N+  +T  V+W  P      ++T + V     K+   V  +    SD    +T L 
Sbjct: 14081 PEVSNVTKNTATVSWKRPVDDGGSEITGYHVERREKKSLRWVRAIKTPVSDLRCKVTGLQ 14140

Query: 1421  PGTEYVVSVSSVYEQHESTPLRGRQKTGLDS-------PTGIDFSDITANSFTVHWIAPR 1473
              G+ Y   VS+        P        +         P+    +D T  S ++ W  P 
Sbjct: 14141 EGSTYEFRVSAENRAGIGPPSEASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLAWGKPH 14200

Query: 1474  ----ATITGYRIRHHPEHFSGRPREDRVPHSR-NSITLTNLTPGTEYVVSIVALN--GRE 1526
                   ITGY + H         ++      R     + +L    +Y   I A+N  G  
Sbjct: 14201 YDGGLEITGYVVEHQKVGDEAWIKDTTGTALRITQFVVPDLQTKEKYNFRISAINDAGVG 14260

Query: 1527  ESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFT 1586
             E  ++   +    ++  D E+ A    +L++      +++R +    G      P  E T
Sbjct: 14261 EPAVIPDVEIVEREMAPDFELDAELRRTLVV---RAGLSIRIFVPIKGR-----PAPEVT 14312

Query: 1587  -VPGSKSTATISGLKPGVDYTITVYAVTGRGD---------SPASSKPISINYRTEIDKP 1636
                 + +    + ++    +T+ +     R D         +PA  K   +N R  +D P
Sbjct: 14313 WTKDNINLKNRANIENTESFTLLIIPECNRYDTGKFVMTIENPAGKKSGFVNVRV-LDTP 14371

Query: 1637  S---QMQVTDVQDNSISVKW----LPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMT 1689
                  ++ TD+  +S+++ W    +   S +T Y V            T T    +    
Sbjct: 14372 GPVLNLRPTDITKDSVTLHWDLPLIDGGSRITNYIVEKREATRKS-YSTATTKCHKCTYK 14430

Query: 1690  IEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDR----PKGLAFTDVDVDSIKIAWES 1745
             + GL    EY   V A+N  G  +P   T           P  L   D+   ++ +AW  
Sbjct: 14431 VTGLSEGCEYFFRVMAENEYGIGEPTETTEPVKASEAPSPPDSLNIMDITKSTVSLAWPK 14490

Query: 1746  PQ----GQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHD--- 1798
             P+     +++ Y +                 G E    ++ L  G EYT  V+A++    
Sbjct: 14491 PKHDGGSKITGYVIEAQRKGSDQWTHITTVKGLE--CVVRNLTEGEEYTFQVMAVNSAGR 14548

Query: 1799  --DMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPM 1856
                 ES+P+I  + T +P        Q    + +       + + G R + T   K G  
Sbjct: 14549 SAPRESRPVIVKEQTMLPELDLRGIYQKLVIAKAGDNIKVEIPVLG-RPKPTVTWKKGDQ 14607

Query: 1857  -----KEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVS----- 1906
                  + +N    ++S +++ +    + +   Y     LT+R   G V  +  +      
Sbjct: 14608 ILKQTQRVNFETTATSTILN-INECVRSDSGPY----PLTARNIVGEVGDVITIQVHDIP 14662

Query: 1907  --PPRRARVTDATETTITISWRTKTE----TITGFQVDAVPANGQTPIQRTIKPDVRSYT 1960
               P    +  + +   +T SW          I+ + V+    +  T ++        +Y 
Sbjct: 14663 GPPTGPIKFDEVSSDFVTFSWDPPENDGGVPISNYVVEMRQTDSTTWVELATTVIRTTYK 14722

Query: 1961  ITGLQPGTDYKIYL-----YTLNDNARSSPVVIDASTAIDAPSNL-RFLATTPNSLLVSW 2014
              T L  G +Y+  +     Y +     S+ +V +    +  P    +  A T +S+ +SW
Sbjct: 14723 ATRLTTGLEYQFRVKAQNRYGVGPGITSACIVANYPFKVPGPPGTPQVTAVTKDSMTISW 14782

Query: 2015  QPP----RARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNN 2070
               P     + I GY ++ ++      + V +          +GL  G  Y   VIA    
Sbjct: 14783 HEPLSDGGSPILGYHVERKERNGILWQTVSKALVPGNIFKSSGLTDGIAYEFRVIAENMA 14842

Query: 2071  QKSEP 2075
              KS+P
Sbjct: 14843 GKSKP 14847



 Score =  116 bits (291), Expect = 2e-25
 Identities = 288/1381 (20%), Positives = 498/1381 (36%), Gaps = 191/1381 (13%)

Query: 766  LDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDT 825
            +D  +  TS  I +   G K    +   ++ G+    ++      P    +  V +  D 
Sbjct: 6548 IDTTAEQTSFRILEAKKGDKGRYKIVLQNKHGKAEGFINLKVIDVPGPVRNLEVTETFDG 6607

Query: 826  SIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETAN-SVTLSDLQPG-VQYNIT 879
             + + W  P     + I GY +V    ++  +  L      +   T++ LQ G V+Y   
Sbjct: 6608 EVSLAWEEPLTDGGSKIIGY-VVERRDIKRKTWVLATDRAESCEFTVTGLQKGGVEYLFR 6666

Query: 880  IYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVT 935
            + A        PV          + D    P ++   +V    V++ W PPE    + +T
Sbjct: 6667 VSARNRVGTGEPVETDNPVEARSKYDVPGPPLNVTITDVNRFGVSLTWEPPEYDGGAEIT 6726

Query: 936  GYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTT 995
             Y +++               + +  A VT +  G  Y F+V A +     KP  A    
Sbjct: 6727 NYVIELRDKTSIRWDTAMTVRAEDLSATVTDVVEGQEYSFRVRAQNRIGVGKPSAATPFV 6786

Query: 996  KL-------DAPTNLQFVNETDSTVLVRWTPP----RAQITGYRLTVGLTRRGQPR---- 1040
            K+         P NL   ++T S+V ++W PP     + I GY   +     G+      
Sbjct: 6787 KVADPIERPSPPVNLTSSDQTQSSVQLKWEPPLKDGGSPILGY--IIERCEEGKDNWIRC 6844

Query: 1041 QYNVGPSVSKYPLRNLQPASE--YTVSLVAIKGNQESPKATGVFTT----LQPGSSIPPY 1094
               + P ++ Y +  L+  ++  Y VS     G  +  +  G  T     ++P   +  +
Sbjct: 6845 NMKLVPELT-YKVTGLEKGNKYLYRVSAENKAGVSDPSEILGPLTADDAFVEPTMDLSAF 6903

Query: 1095 NTEV-----TETTIVI--TWTPAPRIGFKLGVRPSQGGEAPREVT-SDSGSIVVSGLTPG 1146
               +        TI++  T  P P   +  G +  + G+  +  T S    +V+S     
Sbjct: 6904 KDGLEVIVPNPITILVPSTGYPRPTATWCFGDKVLETGDRVKMKTLSAYAELVISPSERS 6963

Query: 1147 VEYVYTIQVLRDGQERDAPI-VNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPD--- 1202
             + +YT+++    +     I VN +  P +P      +   D+  LT  WE    PD   
Sbjct: 6964 DKGIYTLKLENRVKTISGEIDVNVIARPSAPKELKFGDITKDSVHLT--WE---PPDDDG 7018

Query: 1203 ---ITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSV------------ 1247
               +TGY +     + +    + + V       T  +L  G EY   V            
Sbjct: 7019 GSPLTGYVVEKREVSRKTWTKVMDFV--TDLEFTVPDLVQGKEYLFKVCARNKCGPGEPA 7076

Query: 1248 YTVKDDKESVPISDTIIPEVPQLTDLSFVDITDSSIGLRWTPLNS---STIIGYRITVVA 1304
            Y  +    S P +   +P+ P+  ++ + D T +SI L W P  +   S I GY +    
Sbjct: 7077 YVDEPVNMSTPAT---VPDPPE--NVKWRDRTANSIFLTWDPPKNDGGSRIKGYIVERCP 7131

Query: 1305 AGE------GIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQ--- 1355
             G       G P+ E  ++       VTGLE G  Y   V  L   G S P+  T++   
Sbjct: 7132 RGSDKWVACGEPVAETKME-------VTGLEEGKWYAYRVKALNRQGASKPSRPTEEIQA 7184

Query: 1356 --TAVPPPTDLRFTNIGPDTMR----------VTWAPPPSIDLTNFLVRYSPVKNEEDVA 1403
              T   P   L    +   T++          VT  P P I  T    +   +  ++   
Sbjct: 7185 VDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKITWT----KADMILKQDKRI 7240

Query: 1404 ELSISPSDNAVVLTNLL---PGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDI 1460
             +   P  + V + +      GT  + +V+          +    K G   P   D +D+
Sbjct: 7241 TIENVPKKSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNVLDKPG--PPAAFDITDV 7298

Query: 1461 TANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRNS------ITLTNLT 1510
            T  S  + W  PR    + IT Y +         R  +  V H  +S         T L 
Sbjct: 7299 TNESCLLTWNPPRDDGGSKITNYVVER-------RATDSEVWHKLSSTVKDTNFKATKLI 7351

Query: 1511 PGTEYVVSIVALN------GREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAP-- 1562
            P  EY+  + A N        + SP+    Q      P  LE    T  ++ ++W  P  
Sbjct: 7352 PNKEYIFRVAAENMYGVGEPVQASPITAKYQFDPPGPPTRLEPSDITKDAVTLTWCEPDD 7411

Query: 1563 --AVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYA--VTGRGDS 1618
                 +  Y +   +   +  V+   +P   +T  + GL     Y   V A  + G G  
Sbjct: 7412 DGGSPITGYWVERLDPDTDKWVRCNKMPVKDTTYRVKGLTNKKKYRFRVLAENLAGPGKP 7471

Query: 1619 PASSKPISINYRTEID---KPSQMQVTDVQDNSISVKWL----PSSSPVTGYRVTTTPKN 1671
              S++PI I  +  ID    P +  V DV   S+ + W        + +  Y V    K 
Sbjct: 7472 SKSTEPILI--KDPIDPPWPPGKPTVKDVGKTSVRLNWTKPEHDGGAKIESY-VIEMLKT 7528

Query: 1672 GPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQP-------LVQTAVTNID 1724
            G         G   T+  + GL    EY   V A N +GES+P       L +  +    
Sbjct: 7529 GTDEWVRVAEGVPTTQHLLPGLMEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPS 7588

Query: 1725 RPKGLAFTDVDVDSIKIAWESPQ----GQVSRYRVTYSSPEDGIHELFPAPDG--EEDTA 1778
             P+ L   ++  ++  + W  P+      ++ Y V      D   + +   D   ++   
Sbjct: 7589 PPRWLEVINITKNTADLKWTVPEKDGGSPITNYIV---EKRDVRRKGWQTVDTTVKDTKC 7645

Query: 1779 ELQGLRPGSEYTVSVVAL-------HDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSA 1831
             +  L  GS Y   V A        + ++E   L     T    P  L    VT   +  
Sbjct: 7646 TVTPLTEGSLYVFRVAAENAIGQSDYTEIEDSVLAKDTFTTPGPPYALAVVDVTKRHVDL 7705

Query: 1832 QWTPPNVQ--LTGYRVRVTPKEKTGP--MKEINLAPDSSSVVVSGLMVATKYEVSVYALK 1887
            +W PP         R  +  KE+ G   +K    A    +  V+ ++  T+ +  V A  
Sbjct: 7706 KWEPPKNDGGRPIQRYVIEKKERLGTRWVKAGKTAGPDCNFRVTDVIEGTEVQFQVRAEN 7765

Query: 1888 DTLTSRPAQGV-VTTLEN----VSPPRRARVTDATETTITISWRTKTET----ITGFQVD 1938
            +     P++   + ++E+     SPP    VTDA    I I+W+   +     I G+ V+
Sbjct: 7766 EAGVGHPSEPTEILSIEDPTSPPSPPLDLHVTDAGRKHIAIAWKPPEKNGGSPIIGYHVE 7825

Query: 1939 AVPANGQTPIQRTIKP--DVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDA 1996
              P   +  ++   +P  D++     G+ P  +Y + +  +N    S P  I  +     
Sbjct: 7826 MCPVGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAIGVSEPSEISENVVAKD 7885

Query: 1997 P 1997
            P
Sbjct: 7886 P 7886



 Score =  115 bits (288), Expect = 5e-25
 Identities = 291/1449 (20%), Positives = 530/1449 (36%), Gaps = 173/1449 (11%)

Query: 785   KYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPT-VDQVDDTSIVVRWSRPQ----APIT 839
             +Y++ +  ++  G +S+ ++      P  P  P  ++ +      + W RPQ    A I 
Sbjct: 19362 QYVLTLKNVA--GTRSVAVNCKVLDKPGPPAGPLEINGLTAEKCSLSWGRPQEDGGADID 19419

Query: 840   GYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETT 899
              Y +    +   + T         S  ++ L  G +Y   +  V +     P+    E+ 
Sbjct: 19420 YYIVEKRETSHLAWTICEGELQMTSCKVTKLLKGNEYIFRVTGVNKYGVGEPL----ESV 19475

Query: 900   GTPRSD--TVPSP-RDLQFVEVTDVKVTIMWTPPES----AVTGYRVDVIPVN-LPGEHG 951
                  D  TVPSP   L+   VT   +T+ W+ PES     ++GY ++    N L     
Sbjct: 19476 AIKALDPFTVPSPPTSLEITSVTKESMTLCWSRPESDGGSEISGYIIERREKNSLRWVRV 19535

Query: 952   QRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNL-------Q 1004
              + P+  +   + TGL  G  Y ++V+A +    S P       + + P  L       +
Sbjct: 19536 NKKPVY-DLRVKSTGLREGCEYEYRVYAENAAGLSLPSETSPLIRAEDPVFLPSPPSKPK 19594

Query: 1005  FVNETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPAS 1060
              V+   +T+ + W  P     A ITGY +    +     +        ++Y +  L   +
Sbjct: 19595 IVDSGKTTITIAWVKPLFDGGAPITGYTVEYKKSDDTDWKTSIQSLRGTEYTISGLTTGA 19654

Query: 1061  EYTVSLVAIK---GNQESPKATGVFTTLQPGSSIPPYNTEVTETTIV-----ITWT---- 1108
             EY   + ++     +  S  +       +    +   ++E+ +T IV      T T    
Sbjct: 19655 EYVFRVKSVNKVGASDPSDSSDPQIAKEREEEPLFDIDSEMRKTLIVKAGASFTMTVPFR 19714

Query: 1109  --PAPRIGFKLGVRPSQG--GEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDA 1164
               P P +   L  +P       A  + T    S+ +          YT+ +         
Sbjct: 19715 GRPVPNV---LWSKPDTDLRTRAYVDTTDSRTSLTIENANRNDSGKYTLTIQNVLSAASL 19771

Query: 1165  PIVNKVVTPLSPPTNLHLE-ANPDTGVLTVSW---ERSTTPDITGYRITTTPTNGQQGNS 1220
              +V KV+    PPTN+ ++    ++ VL  SW   E      +  Y I     + +   S
Sbjct: 19772 TLVVKVLDTPGPPTNITVQDVTKESAVL--SWDVPENDGGAPVKNYHIEKREASKKAWVS 19829

Query: 1221  LE--------EVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPEVPQLTD 1272
             +         +V +  + +  +  +S   E+ V +    + KE V I++   P  P+   
Sbjct: 19830 VTNNCNRLSYKVTNLQEGAIYYFRVSGENEFGVGIPA--ETKEGVKITEK--PSPPE--K 19883

Query: 1273  LSFVDITDSSIGLRWTPLN---SSTIIGYRITVVAAGEGIPIFEDFVDSSVG---YYTVT 1326
             L    I+  S+ L W        S I+ Y +  +  G+     +++V  +V    ++ V+
Sbjct: 19884 LGVTSISKDSVSLTWLKPEHDGGSRIVHYVVEALEKGQ-----KNWVKCAVAKSTHHVVS 19938

Query: 1327  GLEPGIDYDISVITLINGGESAPT-----TLTQQTAVPPPTDLRFTNIGPDTMRVTWAPP 1381
             GL    +Y   V      G S P       L ++   PP  D++  N    T+ V     
Sbjct: 19939 GLRENSEYFFRVFAENQAGLSDPRELLLPVLIKEQLEPPEIDMK--NFPSHTVYVRAGSN 19996

Query: 1382  PSIDLTNFLVRYSPVKNEEDVAELSISPSDNA-VVLTNLLPGTEYVVSVSSVYEQHESTP 1440
               +D+         V    D   L  +   N  +   NL    +  V+  +   +  +  
Sbjct: 19997 LKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADAGRYEITAAN 20056

Query: 1441  LRGRQKTGLD--------SPTG-IDFSDITANSFTVHWIAPR----ATITGYRIRHHPEH 1487
               G  K  ++         PTG +  SDIT  S T+ W  P+    + +T Y +    E 
Sbjct: 20057 SSGTTKAFINIVVLDRPGPPTGPVVISDITEESVTLKWEPPKYDGGSQVTNYILLKR-ET 20115

Query: 1488  FSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGR------EESPLLIGQQSTVSDV 1541
              +    E     +R  + +  LT G EY   I A N        + + + +    T    
Sbjct: 20116 STAVWTEVSATVARTMMKVMKLTTGEEYQFRIKAENRFGISDHIDSACVTVKLPYTTPGP 20175

Query: 1542  PRDLEVVAATPTSLLISWDAPAVT----VRYYRITYGETGGNSPVQEFTVPGSKSTATIS 1597
             P    V   T  S+ + W  P       V  Y +   +       +   +    +   ++
Sbjct: 20176 PSTPWVTNVTRESITVGWHEPVSNGGSAVVGYHLEMKDRNSILWQKANKLVIRTTHFKVT 20235

Query: 1598  GLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKW---- 1653
              +  G+ Y   VYA    G    S     +      + P  +++TD+  NS+S+ W    
Sbjct: 20236 TISAGLIYEFRVYAENAAGVGKPSHPSEPVLAIDACEPPRNVRITDISKNSVSLSWQQPA 20295

Query: 1654  LPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE-S 1712
                 S +TGY V          TK       +T+  I GL    +Y   V+A+N  G  S
Sbjct: 20296 FDGGSKITGYIVERRDLPDGRWTKASFTNVTETQFIISGLTQNSQYEFRVFARNAVGSIS 20355

Query: 1713  QPL-VQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAP 1771
              P  V   +T ID   G    D+ ++  ++  +   G   + R   S       E +   
Sbjct: 20356 NPSEVVGPITCIDSYGGPVI-DLPLEYTEVV-KYRAGTSVKLRAGISGKPAPTIEWYK-D 20412

Query: 1772  DGEEDTAELQGLRPGSEYTVSVVALHDDMES-------QPLIGTQSTAI---------PA 1815
             D E  T  L  +   ++    ++   D + S       +  +G+ S  I         P 
Sbjct: 20413 DKELQTNALVCVENTTDLASILIKDADRLNSGCYELKLRNAMGSASATIRVQILDKPGPP 20472

Query: 1816  PTDLKFTQVTPTSLSAQWTPP----NVQLTGYRVRVTPKEKTGPM--KEINLAPDSSSVV 1869
                ++F  VT   ++  W PP      ++T Y   +  K +T  +    ++   +   + 
Sbjct: 20473 GGPIEFKTVTAEKITLLWRPPADDGGAKITHY---IVEKRETSRVVWSMVSEHLEECIIT 20529

Query: 1870  VSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENV----SPPRRARVTDATETTITISW 1925
              + ++   +Y   V A+       P +      +N      PP    VT  T+ ++T+ W
Sbjct: 20530 TTKIIKGNEYIFRVRAVNKYGIGEPLESDSVVAKNAFVTPGPPGIPEVTKITKNSMTVVW 20589

Query: 1926  RTKT----ETITGFQV---DAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLN 1978
                       I+G+ +   D         ++ TI+ D R   +TGL   +DY+  +  +N
Sbjct: 20590 SRPIADGGSDISGYFLEKRDKKSLGWFKVLKETIR-DTRQ-KVTGLTENSDYQYRVCAVN 20647

Query: 1979  DNAR---SSPVVI-DASTAIDAP---SNLRFLATTPNSLLVSWQPP----RARITGYIIK 2027
                +   S P     A+  ID P   + +R   +T +S+ + W  P     + +TGY+++
Sbjct: 20648 AAGQGPFSEPSEFYKAADPIDPPGPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVVE 20707

Query: 2028  YEKPGSPPREVVP-RPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQKT 2086
               +        V  +     TE  ++ L+PG  Y   V A+    + EP I   + VQ  
Sbjct: 20708 IRQGEEEEWTTVSTKGEVRTTEYVVSNLKPGVNYYFRVSAVNCAGQGEP-IEMNEPVQAK 20766

Query: 2087  PFVTHPGYD 2095
               +  P  D
Sbjct: 20767 DILEAPEID 20775



 Score =  115 bits (287), Expect = 7e-25
 Identities = 310/1519 (20%), Positives = 528/1519 (34%), Gaps = 242/1519 (15%)

Query: 758  EEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLI---LSTSQTTAPDAP 814
            E GD  +   L + A  V    + P  +    +Y +  +     I   +  +    P AP
Sbjct: 6939 ETGDRVKMKTLSAYAELV----ISPSERSDKGIYTLKLENRVKTISGEIDVNVIARPSAP 6994

Query: 815  PDPTVDQVDDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTLSDL 870
             +     +   S+ + W  P     +P+TGY +        + T++    T    T+ DL
Sbjct: 6995 KELKFGDITKDSVHLTWEPPDDDGGSPLTGYVVEKREVSRKTWTKVMDFVTDLEFTVPDL 7054

Query: 871  QPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP 930
              G +Y   + A  +     P  + +    +  +     P ++++ + T   + + W PP
Sbjct: 7055 VQGKEYLFKVCARNKCGPGEPAYVDEPVNMSTPATVPDPPENVKWRDRTANSIFLTWDPP 7114

Query: 931  E----SAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRES 986
            +    S + GY V+  P           P++  T  EVTGL  G  Y ++V A++    S
Sbjct: 7115 KNDGGSRIKGYIVERCPRGSDKWVACGEPVA-ETKMEVTGLEEGKWYAYRVKALNRQGAS 7173

Query: 987  KP---------------------------LTAQQTTKLDAPTNLQFVNETDSTVLVRWTP 1019
            KP                           LT +  TK++ P  +    E   T    WT 
Sbjct: 7174 KPSRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEPKIT----WT- 7228

Query: 1020 PRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKAT 1079
             +A +   +    +T    P++  V    SK           Y +  V + G   +    
Sbjct: 7229 -KADMI-LKQDKRITIENVPKKSTVTIVDSK-----RSDTGTYIIEAVNVCGRATAVVEV 7281

Query: 1080 GVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRI--GFKLGVRPSQGGEAPREVTSDSGS 1137
             V    +PG       T+VT  + ++TW P PR   G K+     +      EV     S
Sbjct: 7282 NVLD--KPGPPAAFDITDVTNESCLLTWNP-PRDDGGSKITNYVVERRATDSEVWHKLSS 7338

Query: 1138 IV------VSGLTPGVEYVYTI---QVLRDGQERDA-PIVNKV-VTPLSPPTNLHLEANP 1186
             V       + L P  EY++ +    +   G+   A PI  K    P  PPT L   ++ 
Sbjct: 7339 TVKDTNFKATKLIPNKEYIFRVAAENMYGVGEPVQASPITAKYQFDPPGPPTRLE-PSDI 7397

Query: 1187 DTGVLTVSW---ERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEY 1243
                +T++W   +      ITGY +     +  +     ++   D ++     L+   +Y
Sbjct: 7398 TKDAVTLTWCEPDDDGGSPITGYWVERLDPDTDKWVRCNKMPVKD-TTYRVKGLTNKKKY 7456

Query: 1244 NVSVYTV------KDDKESVP--ISDTIIPEVPQLTDLSFVDITDSSIGLRWTPL---NS 1292
               V         K  K + P  I D I P  P     +  D+  +S+ L WT       
Sbjct: 7457 RFRVLAENLAGPGKPSKSTEPILIKDPIDPPWPP-GKPTVKDVGKTSVRLNWTKPEHDGG 7515

Query: 1293 STIIGYRITVVAAG--------EGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLING 1344
            + I  Y I ++  G        EG+P  +         + + GL  G +Y   V  +   
Sbjct: 7516 AKIESYVIEMLKTGTDEWVRVAEGVPTTQ---------HLLPGLMEGQEYSFRVRAVNKA 7566

Query: 1345 GESAPT-----TLTQQTAVP--PPTDLRFTNIGPDTMRVTWAPPP---SIDLTNFLVRYS 1394
            GES P+      L ++   P  PP  L   NI  +T  + W  P       +TN++V   
Sbjct: 7567 GESEPSEPSDPVLCREKLYPPSPPRWLEVINITKNTADLKWTVPEKDGGSPITNYIVEKR 7626

Query: 1395 PVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVS-------SVYEQHESTPLRGRQKT 1447
             V+  +    +  +  D    +T L  G+ YV  V+       S Y + E + L     T
Sbjct: 7627 DVR-RKGWQTVDTTVKDTKCTVTPLTEGSLYVFRVAAENAIGQSDYTEIEDSVLAKDTFT 7685

Query: 1448 GLDSPTGIDFSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRNS 1503
                P  +   D+T     + W  P+      I  Y I       +   +  +      +
Sbjct: 7686 TPGPPYALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKERLGTRWVKAGKTAGPDCN 7745

Query: 1504 ITLTNLTPGTEYVVSIVALN----GREESP---LLIGQQSTVSDVPRDLEVVAATPTSLL 1556
              +T++  GTE    + A N    G    P   L I   ++    P DL V  A    + 
Sbjct: 7746 FRVTDVIEGTEVQFQVRAENEAGVGHPSEPTEILSIEDPTSPPSPPLDLHVTDAGRKHIA 7805

Query: 1557 ISWDAPAVTVRYYRITYGETGGNSPVQEFTVP----GSKSTATIS-------------GL 1599
            I+W  P            E  G SP+  + V     G++    ++             G+
Sbjct: 7806 IAWKPP------------EKNGGSPIIGYHVEMCPVGTEKWMRVNSRPIKDLKFKVEEGV 7853

Query: 1600 KPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSP 1659
             P  +Y + V AV   G     S+P  I+       P      D++ + I V      S 
Sbjct: 7854 VPDKEYVLRVRAVNAIG----VSEPSEISENVVAKDPDCKPTIDLETHDIIVIEGEKLSI 7909

Query: 1660 VTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYA---------QNPSG 1710
               +R    P         +    D+  M  + +   +E   SV A         +N  G
Sbjct: 7910 PVPFRAVPVPTVSWHKDGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLG 7969

Query: 1711 ESQPLVQTAVTNIDRP-KGLAFTDVDVDSIKIAWESPQ--GQVSRYRVTYSSPEDGIHEL 1767
             +   +   V  +  P K +  +D+   S K+ WE P+  G            E G    
Sbjct: 7970 SATASINVKVIGLPGPCKDIKASDITKSSCKLTWEPPEFDGGTPILHYVLERREAGRRTY 8029

Query: 1768 FPAPDGEEDTA-ELQGLRPGSEYTVSVVALH-----DDME-SQPLIGTQSTAIP-APTDL 1819
             P   GE   +  ++ L P  EY   V A++     + +E   P+I       P  P D+
Sbjct: 8030 IPVMSGENKLSWTVKDLIPNGEYFFRVKAVNKVGGGEYIELKNPVIAQDPKQPPDPPVDV 8089

Query: 1820 KFTQVTPTSLSAQWTPP----NVQLTGYRV-RVTPKEKTGPMKEINLAPDSSSVVVSGLM 1874
            +    T  +++  W PP      ++ GY + ++   E+       +L P   +    GL 
Sbjct: 8090 EVHNPTAEAMTITWKPPLYDGGSKIMGYIIEKIAKGEERWKRCNEHLVP-ILTYTAKGLE 8148

Query: 1875 VATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTI------------- 1921
               +Y+  V A      S P++    T + V P    +V   T   +             
Sbjct: 8149 EGKEYQFRVRAENAAGISEPSRATPPT-KAVDPIDAPKVILRTSLEVKRGDEIALDASIS 8207

Query: 1922 -----TISWRTKTETITGFQVD--------------------AVPANGQTPIQRTIKPDV 1956
                 TI+W      I   ++                      +P   +  I  + K + 
Sbjct: 8208 GSPYPTITWIKDENVIVPEEIKKRAAPLVRRRKGEVQEEEPFVLPLTQRLSIDNSKKGES 8267

Query: 1957 RSYTITGLQPGTDYKIYLYTL-NDNA-RSSPVVIDASTAIDAPSNLRFLATTPNSLLVSW 2014
            +      L+P  D+ +Y+  + ND+    +P  +        P N  F      S+L  W
Sbjct: 8268 QLRVRDSLRP--DHGLYMIKVENDHGIAKAPCTVSVLDTPGPPINFVFEDIRKTSVLCKW 8325

Query: 2015 QPP----RARITGYIIKYEKPGSPPRE-VVPRPRPGVTEATITGLEPGTEYTIYVIALKN 2069
            +PP     + I  Y ++ +    P  E +V        + ++T L  G EY ++ +  +N
Sbjct: 8326 EPPLDDGGSEIINYTLEKKDKTKPDSEWIVVTSTLRHCKYSVTKLIEGKEY-LFRVRAEN 8384

Query: 2070 NQKSEPLIGRKKTVQKTPF 2088
                 P    K  V K PF
Sbjct: 8385 RFGPGPPCVSKPLVAKDPF 8403



 Score =  114 bits (286), Expect = 9e-25
 Identities = 280/1356 (20%), Positives = 495/1356 (36%), Gaps = 217/1356 (16%)

Query: 727   SVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQ--YLDLPSTA--TSVNIPDLLP 782
             +VTE+T+   V+SW    D   G ++++ + ++ +  +  + ++ S    T + +  LL 
Sbjct: 15066 AVTEVTSEKCVLSWFPPLDD-GGAKIDHYIVQKRETSRLAWTNVASEVQVTKLKVTKLLK 15124

Query: 783   GRKYI-----VNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAP 837
             G +YI     VN Y + E  E   +L+ +    PD P +P V  +   S+VV W  P + 
Sbjct: 15125 GNEYIFRVMAVNKYGVGEPLESEPVLAVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDS- 15183

Query: 838   ITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQ-------PGVQYNITIYAVEENQEST 890
               G   + +  VE            N  TL+DL+        G +Y   I A      S 
Sbjct: 15184 -DGGSEIINYIVERRDKAGQRWIKCNKKTLTDLRYKVSGLTEGHEYEFRIMAENAAGISA 15242

Query: 891   PVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNL 946
             P                  P + + ++ +   ++I W  P     S +TGY V++    L
Sbjct: 15243 PSPTSPFYKACDTVFKPGPPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIA---L 15299

Query: 947   PGEHGQRLPIS----RNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLD---A 999
             P E   ++       + T   +TGL+    Y  +++A++     +P     T K +    
Sbjct: 15300 PEEDEWQIVTPPAGLKATSYTITGLTENQEYKIRIYAMNSEGLGEPALVPGTPKAEDRML 15359

Query: 1000  PTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPR---QYNVGPSVSKYPLRNL 1056
             P  ++   +    V +R           RL V +  R  P      + G S+ K    ++
Sbjct: 15360 PPEIELDADLRKVVTIR------ACCTLRLFVPIKGRPAPEVKWARDHGESLDK---ASI 15410

Query: 1057  QPASEYTVSLVAIKGNQESPK----------ATGVFTTLQ----PGSSIPPYNTEVTETT 1102
             +  S YT+ +V      +S K          +   F  ++    PG        EVT+T+
Sbjct: 15411 ESTSSYTLLIVGNVNRFDSGKYILTVENSSGSKSAFVNVRVLDTPGPPQDLKVKEVTKTS 15470

Query: 1103  IVITWTPAPRI--GFKLGVRPSQGGEAPREVTS------DSGSIVVSGLTPGVEYVYTIQ 1154
             + +TW P P +  G K+     +  E+ R+  S         S  V  L  G  Y +  +
Sbjct: 15471 VTLTWDP-PLLDGGSKIKNYIVEKRESTRKAYSTVATNCHKTSWKVDQLQEGCSYYF--R 15527

Query: 1155  VLRDGQ------ERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPD---ITG 1205
             VL + +         A  V     PL P     ++   ++  +++SWE+        I G
Sbjct: 15528 VLAENEYGIGLPAETAESVKASERPLPPGKITLMDVTRNS--VSLSWEKPEHDGGSRILG 15585

Query: 1206  YRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYT-----VKDDKE-SVPI 1259
             Y I    T G    +    V   +++ T   L  G EY+  V       + D ++ SVP+
Sbjct: 15586 Y-IVEMQTKGSDKWATCATVKVTEATIT--GLIQGEEYSFRVSAQNEKGISDPRQLSVPV 15642

Query: 1260  --SDTIIPEVPQLTDLSFVDITDSSI------------GLRW----TPLNSSTIIGYRIT 1301
                D +IP   +L   +F  +    +             + W     PL  +T +    T
Sbjct: 15643 IAKDLVIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAEST 15702

Query: 1302  VVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTL---TQQTAV 1358
                    +   +D     VG+Y              V+ L N    A  TL         
Sbjct: 15703 ---ENNSLLTIKDACREDVGHY--------------VVKLTNSAGEAIETLNVIVLDKPG 15745

Query: 1359  PPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAE---LSISPSDNAVV 1415
             PP   ++   +  D++ ++W  PP  D  + +  Y   K +        +S + +   + 
Sbjct: 15746 PPTGPVKMDEVTADSITLSWG-PPKYDGGSSINNYIVEKRDTSTTTWQIVSATVARTTIK 15804

Query: 1416  LTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTG-----LDSPTGIDFSDITA-NSFTVHW 1469
                L  G EY   +++     +ST L            +  P G     +++ +S  V W
Sbjct: 15805 ACRLKTGCEYQFRIAAENRYGKSTYLNSEPTVAQYPFKVPGPPGTPVVTLSSRDSMEVQW 15864

Query: 1470  IAP----RATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGR 1525
               P     + + GY +     +     + ++ P  +     T L  G EY   + A    
Sbjct: 15865 NEPISDGGSRVIGYHLERKERNSILWVKLNKTPIPQTKFKTTGLEEGVEYEFRVSA---- 15920

Query: 1526  EESPLLIGQQSTVSD--VPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQ 1583
              E+ + IG+ S VS+  V RD       P +++++ +  +VT+++ + TY    G S + 
Sbjct: 15921 -ENIVGIGKPSKVSECYVARDPCDPPGRPEAIIVTRN--SVTLQWKKPTY---DGGSKIT 15974

Query: 1584  EFTVPGS--------KSTAT--------ISGLKPGVDYTITVYAVTGRG-DSPASSKPIS 1626
              + V           K++ T        ++GL     Y   V A    G  S  S    +
Sbjct: 15975 GYIVEKKELPEGRWMKASFTNIIDTHFEVTGLVEDHRYEFRVIARNAAGVFSEPSESTGA 16034

Query: 1627  INYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQT 1686
             I  R E+D P        +D  +             ++V       P PT     G  + 
Sbjct: 16035 ITARDEVDPPRISMDPKYKDTIV-------VHAGESFKVDADIYGKPIPTIQWIKGDQEL 16087

Query: 1687  EMTIEGLQPTVEYVVS---------------VYAQNPSGESQPLVQTAVTNIDRP----K 1727
               T      + ++  S               + A+N +GE    V   V  +DRP     
Sbjct: 16088 SNTARLEIKSTDFATSLSVKDAVRVDSGNYILKAKNVAGERSVTVNVKV--LDRPGPPEG 16145

Query: 1728  GLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHEL-FPAPDGEEDT--AELQGLR 1784
              +  + V  +   +AW+ P        + Y         L +   D    T   ++  L 
Sbjct: 16146 PVVISGVTAEKCTLAWKPPLQDGGSDIINYIVERRETSRLVWTVVDANVQTLSCKVTKLL 16205

Query: 1785  PGSEYTVSVVALH-----DDMESQPLIGTQSTAIP-APTDLKFTQVTPTSLSAQWTPP-- 1836
              G+EYT  ++A++     + +ES+P++      +P AP   + T VT  S+   W  P  
Sbjct: 16206 EGNEYTFRIMAVNKYGVGEPLESEPVVAKNPFVVPDAPKAPEVTTVTKDSMIVVWERPAS 16265

Query: 1837  --NVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRP 1894
                 ++ GY +    KE     +          + V+GL+    YE  V A      S P
Sbjct: 16266 DGGSEILGYVLEKRDKEGIRWTRCHKRLIGELRLRVTGLIENHDYEFRVSAENAAGLSEP 16325

Query: 1895  A-----QGVVTTLENVSPPRRARVTDATETTITISW 1925
             +     Q     +    PP   +V D T +++ +SW
Sbjct: 16326 SPPSAYQKACDPIYKPGPPNNPKVIDITRSSVFLSW 16361



 Score =  114 bits (285), Expect = 1e-24
 Identities = 294/1413 (20%), Positives = 501/1413 (35%), Gaps = 193/1413 (13%)

Query: 806  SQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ----APITGYRIVYSPSVEGS-STELNLPE 860
            S+   P  P + T+  V+   + + W  P+    A IT Y I           T + +  
Sbjct: 6689 SKYDVPGPPLNVTITDVNRFGVSLTWEPPEYDGGAEITNYVIELRDKTSIRWDTAMTVRA 6748

Query: 861  TANSVTLSDLQPGVQYNITIYA-----VEENQESTPVVIQQETTGTPRSDTVPSPRDLQF 915
               S T++D+  G +Y+  + A     V +   +TP V   +    P       P +L  
Sbjct: 6749 EDLSATVTDVVEGQEYSFRVRAQNRIGVGKPSAATPFVKVADPIERPSP-----PVNLTS 6803

Query: 916  VEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGV 971
             + T   V + W PP     S + GY ++             + +      +VTGL  G 
Sbjct: 6804 SDQTQSSVQLKWEPPLKDGGSPILGYIIERCEEGKDNWIRCNMKLVPELTYKVTGLEKGN 6863

Query: 972  TYYFKVFAVSHGRESKP------LTA-----QQTTKLDA-PTNLQFVNETDSTVLVRWTP 1019
             Y ++V A +    S P      LTA     + T  L A    L+ +     T+LV  T 
Sbjct: 6864 KYLYRVSAENKAGVSDPSEILGPLTADDAFVEPTMDLSAFKDGLEVIVPNPITILVPSTG 6923

Query: 1020 -PRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKA 1078
             PR   T       L    + +      ++S Y    + P+      +  +K        
Sbjct: 6924 YPRPTATWCFGDKVLETGDRVKM----KTLSAYAELVISPSERSDKGIYTLKLENRVKTI 6979

Query: 1079 TG---VFTTLQPGSSIPPYNTEVTETTIVITWTP------APRIGFKLGVRPSQGGEAPR 1129
            +G   V    +P +       ++T+ ++ +TW P      +P  G+ +  R     E  R
Sbjct: 6980 SGEIDVNVIARPSAPKELKFGDITKDSVHLTWEPPDDDGGSPLTGYVVEKR-----EVSR 7034

Query: 1130 EVTSDSGSIV------VSGLTPGVEYVYTIQVLRDGQERDAPIVNKVV---TPLS---PP 1177
            +  +     V      V  L  G EY++ +         +   V++ V   TP +   PP
Sbjct: 7035 KTWTKVMDFVTDLEFTVPDLVQGKEYLFKVCARNKCGPGEPAYVDEPVNMSTPATVPDPP 7094

Query: 1178 TNLHLEANPDTGVLTVSWERSTTPD---ITGYRITTTPTNGQQGNSLEEVVHADQSSCTF 1234
             N+         +  ++W+         I GY +   P    +  +  E V   +   T 
Sbjct: 7095 ENVKWRDRTANSIF-LTWDPPKNDGGSRIKGYIVERCPRGSDKWVACGEPVAETKMEVT- 7152

Query: 1235 DNLSPGLEYNVSVYTVKDDKESVPISDT-------------IIPEVPQLTDLSF-----V 1276
              L  G  Y   V  +     S P   T             I  +V  L  L+      +
Sbjct: 7153 -GLEEGKWYAYRVKALNRQGASKPSRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKI 7211

Query: 1277 DITDSSIG-----LRWTPLNSSTIIGYRITVVAAGEGIP-----IFEDFVDSSVGYYTVT 1326
            ++  +  G     + WT  +       RIT+    E +P        D   S  G Y + 
Sbjct: 7212 ELPATVTGKPEPKITWTKADMILKQDKRITI----ENVPKKSTVTIVDSKRSDTGTYIIE 7267

Query: 1327 GLEPGIDYDISVITLINGGESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAPPPS--- 1383
             +             + G  +A   +       PP     T++  ++  +TW PP     
Sbjct: 7268 AVN------------VCGRATAVVEVNVLDKPGPPAAFDITDVTNESCLLTWNPPRDDGG 7315

Query: 1384 IDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSS-----VYEQHES 1438
              +TN++V      +E    +LS +  D     T L+P  EY+  V++     V E  ++
Sbjct: 7316 SKITNYVVERRATDSEV-WHKLSSTVKDTNFKATKLIPNKEYIFRVAAENMYGVGEPVQA 7374

Query: 1439 TPLRGR-QKTGLDSPTGIDFSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPR 1493
            +P+  + Q      PT ++ SDIT ++ T+ W  P     + ITGY +           R
Sbjct: 7375 SPITAKYQFDPPGPPTRLEPSDITKDAVTLTWCEPDDDGGSPITGYWVERLDPDTDKWVR 7434

Query: 1494 EDRVPHSRNSITLTNLTPGTEYVVSIVALN-------GREESPLLIGQQSTVSDVPRDLE 1546
             +++P    +  +  LT   +Y   ++A N        +   P+LI         P    
Sbjct: 7435 CNKMPVKDTTYRVKGLTNKKKYRFRVLAENLAGPGKPSKSTEPILIKDPIDPPWPPGKPT 7494

Query: 1547 VVAATPTSLLISWDAP----AVTVRYYRITYGETGGNSPVQEFTVPGSKSTA-TISGLKP 1601
            V     TS+ ++W  P       +  Y I   +TG +  V+     G  +T   + GL  
Sbjct: 7495 VKDVGKTSVRLNWTKPEHDGGAKIESYVIEMLKTGTDEWVR--VAEGVPTTQHLLPGLME 7552

Query: 1602 GVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQ---MQVTDVQDNSISVKWL---- 1654
            G +Y+  V AV   G+S  S     +  R ++  PS    ++V ++  N+  +KW     
Sbjct: 7553 GQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLEVINITKNTADLKWTVPEK 7612

Query: 1655 PSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQ- 1713
               SP+T Y V        G     T   D T+ T+  L     YV  V A+N  G+S  
Sbjct: 7613 DGGSPITNYIVEKRDVRRKGWQTVDTTVKD-TKCTVTPLTEGSLYVFRVAAENAIGQSDY 7671

Query: 1714 ------PLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQ----VSRYRVTYSSPEDG 1763
                   L +   T    P  LA  DV    + + WE P+      + RY +        
Sbjct: 7672 TEIEDSVLAKDTFTTPGPPYALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKERLGT 7731

Query: 1764 IHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPT------ 1817
                     G +    +  +  G+E    V A ++     P   T+  +I  PT      
Sbjct: 7732 RWVKAGKTAGPDCNFRVTDVIEGTEVQFQVRAENEAGVGHPSEPTEILSIEDPTSPPSPP 7791

Query: 1818 -DLKFTQVTPTSLSAQWTPPNVQ----LTGYRVRVTPKEKTGPMKEINLAP--DSSSVVV 1870
             DL  T      ++  W PP       + GY V + P   T     +N  P  D    V 
Sbjct: 7792 LDLHVTDAGRKHIAIAWKPPEKNGGSPIIGYHVEMCP-VGTEKWMRVNSRPIKDLKFKVE 7850

Query: 1871 SGLMVATKYEVSVYALKDTLTSRP---AQGVVTTLENVSP-----PRRARVTDATETTIT 1922
             G++   +Y + V A+     S P   ++ VV    +  P          V +  + +I 
Sbjct: 7851 EGVVPDKEYVLRVRAVNAIGVSEPSEISENVVAKDPDCKPTIDLETHDIIVIEGEKLSIP 7910

Query: 1923 ISWRTKTETITGFQVDAVPANGQTPIQRTIKPD-VRSYTITGLQPGTDYKIYLYTLNDNA 1981
            + +R        +  D         +  T+K D + ++         D  IY  TL +  
Sbjct: 7911 VPFRAVPVPTVSWHKDGKEVKASDRL--TMKNDHISAHLEVPKSVRADAGIYTITLENKL 7968

Query: 1982 RSSPVVIDAST-AIDAP-SNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPP 2035
             S+   I+     +  P  +++    T +S  ++W+PP       I  Y+++  + G   
Sbjct: 7969 GSATASINVKVIGLPGPCKDIKASDITKSSCKLTWEPPEFDGGTPILHYVLERREAGR-- 8026

Query: 2036 REVVP-RPRPGVTEATITGLEPGTEYTIYVIAL 2067
            R  +P          T+  L P  EY   V A+
Sbjct: 8027 RTYIPVMSGENKLSWTVKDLIPNGEYFFRVKAV 8059



 Score =  112 bits (281), Expect = 3e-24
 Identities = 353/1634 (21%), Positives = 588/1634 (35%), Gaps = 247/1634 (15%)

Query: 607   SSSGPVEVFIT----ETPSQPNSHPIQWNAPQPSHISKYILRWRP---------KNSVGR 653
             +SSG    F+T    +TP  P +  ++      +      L W P         KN V  
Sbjct: 17602 NSSGSKSAFVTVKVLDTPGPPQNLAVKEVRKDSA-----FLVWEPPIIDGGAKVKNYVID 17656

Query: 654   WKEATIPGHLN--------SYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTP 705
              +E+T   + N        S+ ++ L  G +Y  ++++  ++G                P
Sbjct: 17657 KRESTRKAYANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFG-------------VGVP 17703

Query: 706   VTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVS----ASDTVSGFRVEYELSEEGD 761
             V +        P SP      ++T+++ +S  + W          V G+ VE  +  +G 
Sbjct: 17704 VETVDAVKAAEPPSP--PGKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVE--MQPKGT 17759

Query: 762   EPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQ 821
             E   +   S   +  +  L  G++Y   V   +E G+    +      A D    P++  
Sbjct: 17760 EKWSIVAESKVCNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKL 17819

Query: 822   VDDTSIVVRWS--RPQAPITGY-RIVYSPSVEGS----STELNLPETANSVTLSDLQPGV 874
               +T  +      + + P+ G  R   S   +G     +T +N+ ETA S  L  ++ G 
Sbjct: 17820 PFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLH-IKEGN 17878

Query: 875   QYNITIYAVEENQESTPV-----VIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTP 929
             + +   Y V     +        VI  E  G P          ++F EV+   V I W P
Sbjct: 17879 KDDFGKYTVTATNSAGTATENLSVIVLEKPGPPVGP-------VRFDEVSADFVVISWEP 17931

Query: 930   PESA----VTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRE 985
             P       ++ Y V+         H     ++R T  ++T L  G  Y F++FA +   +
Sbjct: 17932 PAYTGGCQISNYIVEKRDTTTTTWHMVSATVARTTI-KITKLKTGTEYQFRIFAENRYGK 17990

Query: 986   SKPLTA-----QQTTKLDAPTNLQFVNE-TDSTVLVRWTPP----RAQITGYRLTVGLTR 1035
             S PL +     Q   K   P    FV   +   +LV+W  P      +I GY L      
Sbjct: 17991 SAPLDSKAVIVQYPFKEPGPPGTPFVTSISKDQMLVQWHEPVNDGGTKIIGYHLEQKEKN 18050

Query: 1036  RGQPRQYNVGP-SVSKYPLRNLQPASEY--TVSLVAIKGNQESPKATGVFTTLQPGSSIP 1092
                  + N  P   +K+    L    EY   VS   I G  +  K +  F    P    P
Sbjct: 18051 SILWVKLNKTPIQDTKFKTTGLDEGLEYEFKVSAENIVGIGKPSKVSECFVARDPCD--P 18108

Query: 1093  PYNTE---VTETTIVITW-TPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVE 1148
             P   E   +T   + + W  PA   G K+       G    +     G  + +  T  +E
Sbjct: 18109 PGRPEAIVITRNNVTLKWKKPAYDGGSKI------TGYIVEKKDLPDGRWMKASFTNVLE 18162

Query: 1149  YVYTIQVLRDGQERDAPIV-NKVVTPLSPPT---------------NLHLEAN-PDTGVL 1191
               +T+  L + Q  +  ++        S P+               N  L+    D  V+
Sbjct: 18163 TEFTVSGLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARDEIDAPNASLDPKYKDVIVV 18222

Query: 1192  TVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNL---------SPGLE 1242
                       DI G  I     + + G  LEE     +   T             + G +
Sbjct: 18223 HAGETFVLEADIRGKPIPDVVWS-KDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQ 18281

Query: 1243  YNVSVYTVKDDKESVPISDTIIPEV-PQLTDLSFVDITDSSIGLRWTP--LNSSTIIGYR 1299
             Y + +  V   K S+PI+  ++    P    L    +T     L W P   +    I + 
Sbjct: 18282 YILKLSNVGGTK-SIPITVKVLDRPGPPEGPLKVTGVTAEKCYLAWNPPLQDGGANISHY 18340

Query: 1300  ITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGG-----ESAPTTLTQ 1354
             I        +   +   +     Y VT L PG +Y   V+ +   G     ES P T   
Sbjct: 18341 IIEKRETSRLSWTQVSTEVQALNYKVTKLLPGNEYIFRVMAVNKYGIGEPLESGPVTACN 18400

Query: 1355  QTAVP-PPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISP---S 1410
                 P PP+    + I  D+M VTWA P     T         +++E V     +    +
Sbjct: 18401 PYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDKEGVRWTKCNKKTLT 18460

Query: 1411  DNAVVLTNLLPGTEYVVSVSS-----VYEQHESTPLRGRQKTGL---DSPTGIDFSDITA 1462
             D  + +T L  G  Y   V++     V E  E +    R    L     P+    +D + 
Sbjct: 18461 DLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFY-RACDALYPPGPPSNPKVTDTSR 18519

Query: 1463  NSFTVHWIAP----RATITGYRIRHHPEHFSGRPREDRVPHS---RNSITLTNLTPGTEY 1515
             +S ++ W  P     A + GY +    +  +        P +       T+T L   TEY
Sbjct: 18520 SSVSLAWSKPIYDGGAPVKGYVV--EVKEAAADEWTTCTPPTGLQGKQFTVTKLKENTEY 18577

Query: 1516  VVSIVALN--GREESPLLIGQQSTVSDV-PRDLEVVAATPTSLLISWDAPAVTVRYYRIT 1572
                I A+N  G  E   L G       + P ++E+ A     +++   A   T+R +   
Sbjct: 18578 NFRICAINSEGVGEPATLPGSVVAQERIEPPEIELDADLRKVVVLRASA---TLRLFVTI 18634

Query: 1573  YGETGGNSPVQEFTVPGSKSTAT-ISGLKPGVDYTITVYAVTGRGDS---------PASS 1622
              G      P  E     ++   T  + ++    +T+ V     R DS          + S
Sbjct: 18635 KGR-----PEPEVKWEKAEGILTDRAQIEVTSSFTMLVIDNVTRFDSGRYNLTLENNSGS 18689

Query: 1623  KPISINYRTEIDKPS---QMQVTDVQDNSISVKWLP----SSSPVTGYRV---TTTPKNG 1672
             K   +N R  +D PS    + + +V+ +S+++ W P      + +T Y V    TT K  
Sbjct: 18690 KTAFVNVRV-LDSPSAPVNLTIREVKKDSVTLSWEPPLIDGGAKITNYIVEKRETTRK-- 18746

Query: 1673  PGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPK----G 1728
                  T T    +T   IE LQ    Y   V A N  G   P   T    +  P      
Sbjct: 18747 --AYATITNNCTKTTFRIENLQEGCSYYFRVLASNEYGIGLPAETTEPVKVSEPPLPPGR 18804

Query: 1729  LAFTDVDVDSIKIAWESPQ----GQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLR 1784
             +   DV  ++  I WE P+     +++ Y V   +   G  +       +   A + GL 
Sbjct: 18805 VTLVDVTRNTATIKWEKPESDGGSKITGYVVEMQT--KGSEKWSTCTQVKTLEATISGLT 18862

Query: 1785  PGSEYTVSVVALHDDMESQPL-----IGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQ 1839
              G EY   V A+++   S P      +  +   I    +L F   T    + +    +V 
Sbjct: 18863 AGEEYVFRVAAVNEKGRSDPRQLGVPVIARDIEIKPSVELPFH--TFNVKAREQLKIDVP 18920

Query: 1840  LTGYRVRVTPKEKTG-PMKEINLAPDSSSVVVSGLMV--ATKYEVSVYAL--KDTLTSRP 1894
               G         K G  +KE      SSS  V+ L +  A+K +V  Y L   ++  S  
Sbjct: 18921 FKGRPQATVNWRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSNSAGSIT 18980

Query: 1895  AQGVVTTLENVSPPRRARVTDATETTITISWRTKTE----TITGFQVDAVPANGQT---- 1946
                 +  L+   PP   R+ + +  +ITISW          I+ + V+       T    
Sbjct: 18981 VPITIIVLDRPGPPGPIRIDEVSCDSITISWNPPEYDGGCQISNYIVEKKETTSTTWHIV 19040

Query: 1947  --PIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDA-------- 1996
                + RT      S  I  L  G++Y+  +   N   +SS      S+A+ A        
Sbjct: 19041 SQAVART------SIKIVRLTTGSEYQFRVCAENRYGKSS---YSESSAVVAEYPFSPPG 19091

Query: 1997  -PSNLRFLATTPNSLLVSWQPP----RARITGYIIKYEKPGSPPREVVPRPRPGVTEATI 2051
              P   + +  T +++LV+WQ P     +R+ GY ++Y++  S       +     T+  +
Sbjct: 19092 PPGTPKVVHATKSTMLVTWQVPVNDGGSRVIGYHLEYKERSSILWSKANKILIADTQMKV 19151

Query: 2052  TGLEPGT--EYTIY 2063
             +GL+ G   EY +Y
Sbjct: 19152 SGLDEGLMYEYRVY 19165



 Score =  109 bits (273), Expect = 3e-23
 Identities = 290/1404 (20%), Positives = 524/1404 (37%), Gaps = 190/1404 (13%)

Query: 812   DAPPDPT----VDQVDDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETAN 863
             D P  PT    +  + + S+ ++W  P+    + +T Y ++   +     TE++      
Sbjct: 20071 DRPGPPTGPVVISDITEESVTLKWEPPKYDGGSQVTNYILLKRETSTAVWTEVSATVART 20130

Query: 864   SVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFV-EVTDVK 922
              + +  L  G +Y   I A  EN+      I           T P P    +V  VT   
Sbjct: 20131 MMKVMKLTTGEEYQFRIKA--ENRFGISDHIDSACVTVKLPYTTPGPPSTPWVTNVTRES 20188

Query: 923   VTIMWTPPES----AVTGYRVDVIPVN-LPGEHGQRLPISRNTFAEVTGLSPGVTYYFKV 977
             +T+ W  P S    AV GY +++   N +  +   +L I R T  +VT +S G+ Y F+V
Sbjct: 20189 ITVGWHEPVSNGGSAVVGYHLEMKDRNSILWQKANKLVI-RTTHFKVTTISAGLIYEFRV 20247

Query: 978   FAVSHGRESKPL-TAQQTTKLDA---PTNLQFVNETDSTVLVRWTPPR----AQITGYRL 1029
             +A +     KP   ++    +DA   P N++  + + ++V + W  P     ++ITGY  
Sbjct: 20248 YAENAAGVGKPSHPSEPVLAIDACEPPRNVRITDISKNSVSLSWQQPAFDGGSKITGYI- 20306

Query: 1030  TVGLTRRGQP-----RQYNVGPSVSKYPLRNLQPASEYTVSLVA--IKGNQESP-KATGV 1081
                + RR  P     +      + +++ +  L   S+Y   + A    G+  +P +  G 
Sbjct: 20307 ---VERRDLPDGRWTKASFTNVTETQFIISGLTQNSQYEFRVFARNAVGSISNPSEVVGP 20363

Query: 1082  FTTLQ----PGSSIPPYNTEVTE----TTIV----ITWTPAPRI-GFKLGVRPSQGGEAP 1128
              T +     P   +P   TEV +    T++     I+  PAP I  +K            
Sbjct: 20364 ITCIDSYGGPVIDLPLEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVC 20423

Query: 1129  REVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDT 1188
              E T+D  SI++          Y +++        A I  +++    PP           
Sbjct: 20424 VENTTDLASILIKDADRLNSGCYELKLRNAMGSASATIRVQILDKPGPPGGPIEFKTVTA 20483

Query: 1189  GVLTVSWERSTTPD----ITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYN 1244
               +T+ W R    D    IT Y +    T+    + + E  H ++   T   +  G EY 
Sbjct: 20484 EKITLLW-RPPADDGGAKITHYIVEKRETSRVVWSMVSE--HLEECIITTTKIIKGNEYI 20540

Query: 1245  VSVYTVKDDKESVPI-SDTII----------PEVPQLTDLSFVDITDSSIGLRWT-PL-- 1290
               V  V       P+ SD+++          P +P++T      IT +S+ + W+ P+  
Sbjct: 20541 FRVRAVNKYGIGEPLESDSVVAKNAFVTPGPPGIPEVT-----KITKNSMTVVWSRPIAD 20595

Query: 1291  NSSTIIGYRITVVAAGEGIPIFEDFVDSSVGYY------------TVTGLEPGIDYDISV 1338
               S I GY              E     S+G++             VTGL    DY   V
Sbjct: 20596 GGSDISGY------------FLEKRDKKSLGWFKVLKETIRDTRQKVTGLTENSDYQYRV 20643

Query: 1339  ITLINGGE---SAPTTLTQQTAVP-----PPTDLRFTNIGPDTMRVTWAPP---PSIDLT 1387
               +   G+   S P+    + A P     PP  +R  +    ++ + W+ P       +T
Sbjct: 20644 CAVNAAGQGPFSEPSEF-YKAADPIDPPGPPAKIRIADSTKSSITLGWSKPVYDGGSAVT 20702

Query: 1388  NFLVRYSPVKNEE-DVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQ- 1445
              ++V     + EE               V++NL PG  Y   VS+V    +  P+   + 
Sbjct: 20703 GYVVEIRQGEEEEWTTVSTKGEVRTTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEMNEP 20762

Query: 1446  ---KTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPHSRN 1502
                K  L++P  ID       S           +  ++ R  P     +  ++    +R 
Sbjct: 20763 VQAKDILEAPE-IDLDVALRTSVIAKAGEDVQVLIPFKGRPPPTVTWRKDEKNLGSDARY 20821

Query: 1503  SI---------TLTNLTPGT--EYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAAT 1551
             SI         T+  +T     +Y+++I    G  +S  +  +        + L+V   +
Sbjct: 20822 SIENTDSSSLLTIPQVTRNDTGKYILTIENGVGEPKSSTVSVKVLDTPAACQKLQVKHVS 20881

Query: 1552  PTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGL-----KPGVDYT 1606
               ++ + WD P +      I Y     ++  + ++V   K ++T   L     K    + 
Sbjct: 20882 RGTVTLLWDPPLIDGGSPIINYVIEKRDATKRTWSVVSHKCSSTSFKLIDLSEKTPFFFR 20941

Query: 1607  ITVYAVTGRGDSPASSKPISINYRTEIDKP-SQMQVTDVQDNSISVKW----LPSSSPVT 1661
             +      G G+   +++P+      E+  P   + + D    S+ + W        S +T
Sbjct: 20942 VLAENEIGIGEPCETTEPVK---AAEVPAPIRDLSMKDSTKTSVILSWTKPDFDGGSVIT 20998

Query: 1662  GYRVTTTPKNGPGPTKTKTAGPDQT-EMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAV 1720
              Y V    + G G      AG  +T E+ +  L+        V+A+N  G S P+    +
Sbjct: 20999 EYVV---ERKGKGEQTWSHAGISKTCEIEVSQLKEQSVLEFRVFAKNEKGLSDPVTIGPI 21055

Query: 1721  TNIDRPKGLAFT-DVDVDSIKIAWESPQ-GQVSRYRVTY-SSPEDGIHEL---FPAPDGE 1774
             T     K L  T +VD+  I  A  + + G      + Y   P+  I  L    P  + E
Sbjct: 21056 T----VKELIITPEVDLSDIPGAQVTVRIGHNVHLELPYKGKPKPSISWLKDGLPLKESE 21111

Query: 1775  -------EDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPT----DLKFTQ 1823
                    E+   L       E+      + D+   +  +      +  P+     ++F +
Sbjct: 21112 FVRFSKTENKITLSIKNAKKEHGGKYTVILDNAVCRIAVPITVITLGPPSKPKGPIRFDE 21171

Query: 1824  VTPTSLSAQWTPP----NVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKY 1879
             +   S+   W  P      ++T Y +      +T   K +  +   ++  V  L+   +Y
Sbjct: 21172 IKADSVILSWDVPEDNGGGEITCYSIEKRETSQTN-WKMVCSSVARTTFKVPNLVKDAEY 21230

Query: 1880  EVSVYALKDTLTSRPAQGVVTTLEN----VSPPRRARVTDATETTITISWRTKT----ET 1931
             +  V A      S+P    +   ++      PP +  + + T   ++++W          
Sbjct: 21231 QFRVRAENRYGVSQPLVSSIIVAKHQFRIPGPPGKPVIYNVTSDGMSLTWDAPVYDGGSE 21290

Query: 1932  ITGFQVDAVPANGQTPIQRTIKP-DVRSYTITGLQPGTDYKIYLYTLNDNARSSP----V 1986
             +TGF V+    N     +    P   R Y  TGL  G DY+  +Y  N    SSP     
Sbjct: 21291 VTGFHVEKKERNSILWQKVNTSPISGREYRATGLVEGLDYQFRVYAENSAGLSSPSDPSK 21350

Query: 1987  VIDASTAIDAPSNLRFLATTPNSLLVSWQPP----RARITGYIIKYEKPGSPPREVVPRP 2042
                A + +D P    ++  T  ++ + W PP     ++I GY I+ ++ G+         
Sbjct: 21351 FTLAVSPVDPPGTPDYIDVTRETITLKWNPPLRDGGSKIVGYSIE-KRQGNERWVRCNFT 21409

Query: 2043  RPGVTEATITGLEPGTEYTIYVIA 2066
                  + T+TGL PG  Y   +IA
Sbjct: 21410 DVSECQYTVTGLSPGDRYEFRIIA 21433



 Score =  109 bits (272), Expect = 4e-23
 Identities = 299/1423 (21%), Positives = 501/1423 (35%), Gaps = 243/1423 (17%)

Query: 728   VTEITASSFVVSW----VSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPG 783
             +++I A +  +SW          ++ + VE      GD    L    T TS  +  L+PG
Sbjct: 12504 ISDIDADACSLSWHIPLEDGGSNITNYIVEKCDVSRGDWVTAL-ASVTKTSCRVGKLIPG 12562

Query: 784   RKYIVNV-----YQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ--- 835
             ++YI  V     + ISE      +++      P  P +  V +V+   I V W RP    
Sbjct: 12563 QEYIFRVRAENRFGISEPLTSPKMVAQFPFGVPSEPKNARVTKVNKDCIFVAWDRPDSDG 12622

Query: 836   -APITGYRIVYSPS-----VEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQES 889
              +PI GY I          V+ + T +   E       + L  G++Y+  IYA+ +   S
Sbjct: 12623 GSPIIGYLIERKERNSLLWVKANDTLVRSTE----YPCAGLVEGLEYSFRIYALNKAGSS 12678

Query: 890   TPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPVN 945
              P    +  T     D    P   + ++VT   V+++W  P+    S + GY V+     
Sbjct: 12679 PPSKPTEYVTARMPVDPPGKP---EVIDVTKSTVSLIWARPKHDGGSKIIGYFVEA--CK 12733

Query: 946   LPGEHGQRLPISRNTFAE----VTGLSPGVTYYFKVF---AVSHGRESKPLTAQQTTKLD 998
             LPG+   R   + +   +     TGL     Y F+     AV+    S+P         +
Sbjct: 12734 LPGDKWVRCNTAPHQIPQEEYTATGLEEKAQYQFRAIARTAVNISPPSEPSDPVTILAEN 12793

Query: 999   APTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQ----------YNVGPSV 1048
              P  +       S + V+         G  + +  T  G+P                  +
Sbjct: 12794 VPPRIDLSVAMKSLLTVK--------AGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGI 12845

Query: 1049  SKYPLRNL----------QPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEV 1098
                  RNL          + + +YT++     G++ +     V    +PG   PP + ++
Sbjct: 12846 KMAMQRNLCTLELFSVNRKDSGDYTITAENSSGSKSATIKLKVLD--KPG---PPASVKI 12900

Query: 1099  TE---TTIVITWTPAPRIG------FKLGVR-PSQGGEAPREVTSDSGSIVVSGLTPGVE 1148
              +      +++W P    G      + +  R  S+   A    T    S  V  L  G E
Sbjct: 12901 NKMYSDRAMLSWEPPLEDGGSEITNYIVDKRETSRPNWAQVSATVPITSCSVEKLIEGHE 12960

Query: 1149  YVYTIQVLRDGQERDAPIVNKVV--TPLSPPTNLH--LEANPDTGVLTVSWERSTT---P 1201
             Y + I         D       +   P  PP      + +N     +TVSW+        
Sbjct: 12961 YQFRICAENKYGVGDPVFTEPAIAKNPYDPPGRCDPPVISNITKDHMTVSWKPPADDGGS 13020

Query: 1202  DITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTV--------KDD 1253
              ITGY +    T       +      ++ +     L  G EY   V  +         D 
Sbjct: 13021 PITGYLLEKRETQAVNWTKVNRKPIIER-TLKATGLQEGTEYEFRVTAINKAGPGKPSDA 13079

Query: 1254  KESVPISDTIIPEVPQLTDLSFVDITDSSIGLRWTPL---NSSTIIGYRITVVAAGEGIP 1310
              ++    D   P  P      + D T SS+ L W        S IIGY + V  A     
Sbjct: 13080 SKAAYARDPQYPPGPPAFPKVY-DTTRSSVSLSWGKPAYDGGSPIIGYLVEVKRADS--- 13135

Query: 1311  IFEDFVDSSVGY------YTVTGLEPGIDYDISVITLINGGESAPTTL-----TQQTAVP 1359
               +++V  ++        + VTGL     Y   V  +   G S P+ +      +   +P
Sbjct: 13136 --DNWVRCNLPQNLQKTRFEVTGLMEDTQYQFRVYAVNKIGYSDPSDVPDKHYPKDILIP 13193

Query: 1360  P----PTDLRFTNI--GPDTMR----VTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISP 1409
             P      DLR T I     TMR    V   PPP I  +       P  N  D   L I  
Sbjct: 13194 PEGELDADLRKTLILRAGVTMRLYVPVKGRPPPKITWS------KPNVNLRDRIGLDIKS 13247

Query: 1410  SDNAVVL----TNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSF 1465
             +D    L     N     +Y++++ +   + E T +     T    P  +   +I+ +S 
Sbjct: 13248 TDFDTFLRCENVNKYDAGKYILTLENSCGKKEYTIVVKVLDTP-GPPVNVTVKEISKDSA 13306

Query: 1466  TVHWIAP----RATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVA 1521
              V W  P     + I  Y ++                 S+ S  + NL  G  Y   + A
Sbjct: 13307 YVTWEPPIIDGGSPIINYVVQKRDAERKSWSTV-TTECSKTSFRVANLEEGKSYFFRVFA 13365

Query: 1522  LNGREESPLLIGQQSTVSDVPR---------DLEVVAATPTSLLISWDAPAVTVRYYRIT 1572
                  E+   IG      D  +         DL+V + + +S  I W  P        I 
Sbjct: 13366 -----ENEYGIGDPGETRDAVKASQTPGPVVDLKVRSVSKSSCSIGWKKPHSDGGSRIIG 13420

Query: 1573  YGETGGNSPVQEFTVPGSKSTATISGLK---------PGVDYTITVYAVTGRGDSPASSK 1623
             Y        V +F    +K    +  L           G +YT  V A    G+   S  
Sbjct: 13421 Y--------VVDFLTEENKWQRVMKSLSLQYSAKDLTEGKEYTFRVSAENENGEGTPSE- 13471

Query: 1624  PISINYRTEIDKPSQMQVTDVQDNSISVKWLPS----SSPVTGYRVTTTPKNGPGPTKTK 1679
              I++  R ++  P            + +K LP     +   + +R+    K  P P+ + 
Sbjct: 13472 -ITVVARDDVVAP-----------DLDLKGLPDLCYLAKENSNFRLKIPIKGKPAPSVSW 13519

Query: 1680  TAGPD----QTEMTIEGLQPTVEYVV-----------SVYAQNPSGESQPLVQTAVTNID 1724
               G D     T +++E        +V           ++  +N +G  +  +   V    
Sbjct: 13520 KKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKEGTISIKVVGKP 13579

Query: 1725  R-PKG-LAFTDVDVDSIKIAWESPQGQVSRYRVTY-SSPEDGIHELFP--APDGEEDTAE 1779
               P G + F +V  +++ + W  P+         Y     D ++  +   A   ++ T  
Sbjct: 13580 GIPTGPIKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDSVNNKWVTCASAVQKTTFR 13639

Query: 1780  LQGLRPGSEYTVSVVA-----LHDDMESQPLIGTQSTAIP-APTDLKFTQVTPTSLSAQW 1833
             +  L  G EYT  V A     + + ++S+P++      +P AP       V   S+S  W
Sbjct: 13640 VTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVPDAPPPPNIVDVRHDSVSLTW 13699

Query: 1834  TPP----NVQLTGYRVRVTPKEKTGPM-KEINLAP-DSSSVVVSGLMVATKYEVSVYAL- 1886
             T P       +TGY +    KE+   + K  N  P       V+GL    +YE  V A+ 
Sbjct: 13700 TDPKKTGGSPITGYHLEF--KERNSLLWKRANKTPIRMRDFKVTGLTEGLEYEFRVMAIN 13757

Query: 1887  -----KDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKT----ETITGFQV 1937
                  K +L S P    V  L+ + PP +  V + T  ++T+ W          +TG+ V
Sbjct: 13758 LAGVGKPSLPSEP----VVALDPIDPPGKPEVINITRNSVTLIWTEPKYDGGHKLTGYIV 13813

Query: 1938  DA--VPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLN 1978
             +   +P+           P+  ++T+T L  G  Y+  +   N
Sbjct: 13814 EKRDLPSKSWMKANHVNVPEC-AFTVTDLVEGGKYEFRIRAKN 13855



 Score =  108 bits (269), Expect = 8e-23
 Identities = 265/1341 (19%), Positives = 468/1341 (34%), Gaps = 163/1341 (12%)

Query: 780   LLPGRKYIVNVYQISEDGE----QSLILSTSQTTAPDAPPD-PTVDQVDDTSIVVRWSRP 834
             L+ G +YI  V  ++  G+    QS  +       P  PP+ P V  V   +  V W RP
Sbjct: 14039 LIQGNEYIFRVSAVNHYGKGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSWKRP 14098

Query: 835   Q----APITGYRIVYSPSVEGSSTE-LNLPETANSVTLSDLQPGVQYNITIYA-----VE 884
                  + ITGY +             +  P +     ++ LQ G  Y   + A     + 
Sbjct: 14099 VDDGGSEITGYHVERREKKSLRWVRAIKTPVSDLRCKVTGLQEGSTYEFRVSAENRAGIG 14158

Query: 885   ENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPES----AVTGYRVD 940
                E++  V+ ++    P   + P   D      T    ++ W  P       +TGY V+
Sbjct: 14159 PPSEASDSVLMKDAAYPPGPPSNPHVTD-----TTKKSASLAWGKPHYDGGLEITGYVVE 14213

Query: 941   VIPVN----LPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQ--QT 994
                V     +    G  L I++     V  L     Y F++ A++     +P      + 
Sbjct: 14214 HQKVGDEAWIKDTTGTALRITQFV---VPDLQTKEKYNFRISAINDAGVGEPAVIPDVEI 14270

Query: 995   TKLDAPTNLQFVNETDSTVLVR-------WTP----PRAQITGYRLTVGLTRRGQPRQYN 1043
              + +   + +   E   T++VR       + P    P  ++T  +  + L  R       
Sbjct: 14271 VEREMAPDFELDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKNRANIENTE 14330

Query: 1044  VGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTI 1103
                ++   P  N     ++ +++    G +       V  T  P  ++ P  T++T+ ++
Sbjct: 14331 -SFTLLIIPECNRYDTGKFVMTIENPAGKKSGFVNVRVLDTPGPVLNLRP--TDITKDSV 14387

Query: 1104  VITWT-PAPRIGFKLGVRPSQGGEAPREVTSDSGS------IVVSGLTPGVEYVYTIQVL 1156
              + W  P    G ++     +  EA R+  S + +        V+GL+ G EY + +   
Sbjct: 14388 TLHWDLPLIDGGSRITNYIVEKREATRKSYSTATTKCHKCTYKVTGLSEGCEYFFRVMAE 14447

Query: 1157  RD---GQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPD---ITGYRITT 1210
              +   G+  +     K     SPP +L++  +     ++++W +        ITGY I  
Sbjct: 14448 NEYGIGEPTETTEPVKASEAPSPPDSLNI-MDITKSTVSLAWPKPKHDGGSKITGYVIEA 14506

Query: 1211  TPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISD--TIIPEVP 1268
                   Q   +  V   +   C   NL+ G EY   V  V     S P      I+ E  
Sbjct: 14507 QRKGSDQWTHITTVKGLE---CVVRNLTEGEEYTFQVMAVNSAGRSAPRESRPVIVKEQT 14563

Query: 1269  QLTDLSFVDITDSSIGLRWTPLNSSTI--IGYRITVVAAGEGIPI--------FEDFVDS 1318
              L +L    I    +  +        I  +G     V   +G  I        FE    S
Sbjct: 14564 MLPELDLRGIYQKLVIAKAGDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATS 14623

Query: 1319  SVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTW 1378
             ++             Y ++   ++       T        PP   ++F  +  D +  +W
Sbjct: 14624 TILNINECVRSDSGPYPLTARNIVGEVGDVITIQVHDIPGPPTGPIKFDEVSSDFVTFSW 14683

Query: 1379  APPPS---IDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSS---- 1431
              PP +   + ++N++V      +   V EL+ +        T L  G EY   V +    
Sbjct: 14684 DPPENDGGVPISNYVVEMRQTDSTTWV-ELATTVIRTTYKATRLTTGLEYQFRVKAQNRY 14742

Query: 1432  -VYEQHESTPLRGRQKTGLDSPTGI-DFSDITANSFTVHWIAP----RATITGYRIRHHP 1485
              V     S  +       +  P G    + +T +S T+ W  P     + I GY +    
Sbjct: 14743 GVGPGITSACIVANYPFKVPGPPGTPQVTAVTKDSMTISWHEPLSDGGSPILGYHVERKE 14802

Query: 1486  EHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN-------GREESPLLIGQQSTV 1538
              +        +     N    + LT G  Y   ++A N        +   P+L       
Sbjct: 14803 RNGILWQTVSKALVPGNIFKSSGLTDGIAYEFRVIAENMAGKSKPSKPSEPMLALDPIDP 14862

Query: 1539  SDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPG----SKSTA 1594
                P  L +   T T   + W  P  T  +   +Y     + P   +         ++  
Sbjct: 14863 PGKPVPLNITRHTVT---LKWAKPEYTGGFKITSYIVEKRDLPNGRWLKANFSNILENEF 14919

Query: 1595  TISGLKPGVDYTITVYAVTGRGD-SPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKW 1653
             T+SGL     Y   V A    G  SP S    +I  R +++ P        +D  I    
Sbjct: 14920 TVSGLTEDAAYEFRVIAKNAAGAISPPSEPSDAITCRDDVEAPKIKVDVKFKDTVI---- 14975

Query: 1654  LPSSSPVTGYRVTTTPKNGPGPTK------TKTAGPDQTEMTIEGLQPTV---------E 1698
                      +R+       P PT        +  G  + E+ I      +          
Sbjct: 14976 ---LKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDS 15032

Query: 1699  YVVSVYAQNPSGESQPLVQTAVTNIDRP----KGLAFTDVDVDSIKIAWESP---QGQVS 1751
                ++ A NP G ++ +    V  +DRP      LA T+V  +   ++W  P    G   
Sbjct: 15033 GAYTLTATNPGGFAKHIFNVKV--LDRPGPPEGPLAVTEVTSEKCVLSWFPPLDDGGAKI 15090

Query: 1752  RYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALH-----DDMESQPLI 1806
              + +        +     A + +    ++  L  G+EY   V+A++     + +ES+P++
Sbjct: 15091 DHYIVQKRETSRLAWTNVASEVQVTKLKVTKLLKGNEYIFRVMAVNKYGVGEPLESEPVL 15150

Query: 1807  GTQSTAIP-APTDLKFTQVTPTSLSAQWTPPN----VQLTGYRVRVTPKEKTGPMKEINL 1861
                    P  P + + T +T  S+   W  P+     ++  Y V    K     +K    
Sbjct: 15151 AVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEIINYIVERRDKAGQRWIKCNKK 15210

Query: 1862  APDSSSVVVSGLMVATKYEVSVYA-----LKDTLTSRPAQGVVTTLENVSPPRRARVTDA 1916
                     VSGL    +YE  + A     +     + P      T+    PP   RV D 
Sbjct: 15211 TLTDLRYKVSGLTEGHEYEFRIMAENAAGISAPSPTSPFYKACDTVFKPGPPGNPRVLDT 15270

Query: 1917  TETTITISWRTKT----ETITGFQVD-AVPANGQTPIQRTIKP----DVRSYTITGLQPG 1967
             + ++I+I+W          ITG+ V+ A+P   +  I   + P       SYTITGL   
Sbjct: 15271 SRSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQI---VTPPAGLKATSYTITGLTEN 15327

Query: 1968  TDYKIYLYTLNDNARSSPVVI 1988
              +YKI +Y +N      P ++
Sbjct: 15328 QEYKIRIYAMNSEGLGEPALV 15348



 Score =  107 bits (268), Expect = 1e-22
 Identities = 324/1575 (20%), Positives = 574/1575 (36%), Gaps = 187/1575 (11%)

Query: 552   RWKCDPVDQCQDSETGTFYQIGDSWEKYVHGVRYQCYCY-----GRGIGEWHCQPLQTYP 606
             RWK    D  +    G  Y++       + G  YQ   Y     G G       P     
Sbjct: 9865  RWKRVNRDPIKAMTLGVSYKVTG----LIEGSDYQFRVYAINAAGVGPASLPSDPATARD 9920

Query: 607   SSSGPVEVFITETPSQPNSHPIQWNAPQP---SHISKYILRWRP--KNSVGRWKEATIPG 661
               + P   F   T    +S  ++W+ P     S ++ YI+ ++   K    + K+  + G
Sbjct: 9921  PIAPPGPPFPKVTDWTKSSADLEWSPPLKDGGSKVTGYIVEYKEEGKEEWEKGKDKEVRG 9980

Query: 662   HLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPL 721
                   + GLK G  Y+ ++ ++   G  E              + S  +  + +    +
Sbjct: 9981  --TKLVVTGLKEGAFYKFRVRAVNIAGIGEPGEVT-DVIEMKDRLVSPDLQLDASVRDRI 10037

Query: 722   VATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTA--TSVNIPD 779
             V  +  V  I      +++VS     +   V + ++E    PQ   + +TA  +S+ I +
Sbjct: 10038 VVHAGGVIRI------IAYVSGKPPPT---VTWNMNER-TLPQEATIETTAISSSMVIKN 10087

Query: 780   LLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTV-DQVDDTSIVVRWSRPQ--- 835
                  + + ++   +E GE+   +       P     P +   + + S  + W  P+   
Sbjct: 10088 CQRSHQGVYSLLAKNEAGERKKTIIVDVLDVPGPVGTPFLAHNLTNESCKLTWFSPEDDG 10147

Query: 836   -APITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVI 894
              +PIT Y I    S   + T +    T  + T+  L  G  Y   I A E +    P V 
Sbjct: 10148 GSPITNYVIEKRESDRRAWTPVTYTVTRQNATVQGLIQGKAYFFRI-AAENSIGMGPFVE 10206

Query: 895   QQETTGTPRSDTVPS-PRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPVNLPGE 949
               E        TVP  P DL+  EVT   VT+ W PP+    S +  Y   V+   L G 
Sbjct: 10207 TSEALVIREPITVPERPEDLEVKEVTKNTVTLTWNPPKYDGGSEIINY---VLESRLIGT 10263

Query: 950   HGQRLPISRNTFAE---VTGLSPGVTYYFKVFAVS---HGRES---KPLT-----AQQTT 995
                    + N  +    V GL  G TY ++V AV+    G+ S   KP+T     A  T 
Sbjct: 10264 EKFHKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGKPSFCTKPITCKDELAPPTL 10323

Query: 996   KLDAPTNLQF-VNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLR 1054
              LD    L   V E  +        P+ +++ ++    +    +        +++   ++
Sbjct: 10324 HLDFRDKLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATLALEKIK 10383

Query: 1055  -NLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYN-TEVTETTIVITWTP--- 1109
                  + +Y V +    G+++      V    +PG  + P +  EVT+  +VI+W P   
Sbjct: 10384 AKRSDSGKYCVVVENSTGSRKGFCQVNVVD--RPGPPVGPVSFDEVTKDYMVISWKPPLD 10441

Query: 1110  --APRIGFKLGVRPSQGGEAPREVTSDSGSIV--VSGLTPGVEYVYTIQV-----LRDGQ 1160
                 +I   +  +   G +    VTS S      VS L  G +Y++ I       + D  
Sbjct: 10442 DGGSKITNYIIEKKEVGKDVWMPVTSASAKTTCKVSKLLEGKDYIFRIHAENLYGISDPL 10501

Query: 1161  ERDA-PIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGN 1219
               D+    ++   P +P   +  E   D+ ++T +        IT Y +    T  ++  
Sbjct: 10502 VSDSMKAKDRFRVPDAPDQPIVTEVTKDSALVTWNKPHDGGKPITNYILEKRETMSKRWA 10561

Query: 1220  SLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKD------DKESVPI--SDTIIPEVPQLT 1271
              + +      +     +L  G +Y   V    +         S P+   D I    P + 
Sbjct: 10562 RVTKDPIHPYTKFRVPDLLEGCQYEFRVSAENEIGIGDPSPPSKPVFAKDPIAKPSPPVN 10621

Query: 1272  DLSFVDITDSSIGLRWTPL---NSSTIIGYRITVVAAGEGIPIFEDFVDSSV--GYYTVT 1326
                 +D T +S+ L W P      S I+GY +     G+      +    S     Y VT
Sbjct: 10622 P-EAIDTTCNSVDLTWQPPRHDGGSKILGYIVEYQKVGDEEWRRANHTPESCPETKYKVT 10680

Query: 1327  GLEPGIDYDISVITLINGGESAPTTLTQQTAV----PPPTDLRFTNIG-------PDTMR 1375
             GL  G  Y   V+ +   GES P  + +   V     PP  +   N+         DT+R
Sbjct: 10681 GLRDGQTYKFRVLAVNAAGESDPAHVPEPVLVKDRLEPPELILDANMAREQHIKVGDTLR 10740

Query: 1376  ----VTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLL--PGTEYVVSV 1429
                 +   P P +       R +P K     A + ++P  + + + N     G  Y ++V
Sbjct: 10741 LSAIIKGVPFPKVTWKK-EDRDAPTK-----ARIDVTPVGSKLEIRNAAHEDGGIYSLTV 10794

Query: 1430  SS-VYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAP----RATITGYRIRHH 1484
              +    +  S  +    K G   P  ++ S+I  +S  + W  P     + IT Y +   
Sbjct: 10795 ENPAGSKTVSVKVLVLDKPG--PPRDLEVSEIRKDSCYLTWKEPLDDGGSVITNYVVERR 10852

Query: 1485  PEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVS----- 1539
              +  S +         + S    +L  G +Y+  + A N     P +   +   +     
Sbjct: 10853 -DVASAQWSPLSATSKKKSHFAKHLNEGNQYLFRVAAENQYGRGPFVETPKPIKALDPLH 10911

Query: 1540  --DVPRDLEVVAATPTSLLISWDAP----AVTVRYYRITYGETGGNSPVQEFTVPGSKST 1593
                 P+DL  V    T + + W+ P       +  Y + Y E G    ++  TV  +   
Sbjct: 10912 PPGPPKDLHHVDVDKTEVSLVWNKPDRDGGSPITGYLVEYQEEGTQDWIKFKTV--TNLE 10969

Query: 1594  ATISGLKPGVDYTITVYA--VTGRGDSPASSKPISINYR-----TEIDKPSQMQVTDVQD 1646
               ++GL+ G  Y   V A  + G G  P ++ PI    +      E+D      +     
Sbjct: 10970 CVVTGLQQGKTYRFRVKAENIVGLG-LPDTTIPIECQEKLVPPSVELDVKLIEGLVVKAG 11028

Query: 1647  NSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTE-----MTIEGL--QPTVEY 1699
              ++    +    PV   + TT         KT      +T+     +TI+    + T EY
Sbjct: 11029 TTVRFPAIIRGVPVPTAKWTTDGSE----IKTDEHYTVETDNFSSVLTIKNCLRRDTGEY 11084

Query: 1700  VVSVYAQNPSGESQPLVQTAVTNIDRPK--GLAFTDVDVDSIKIAWESPQGQVSRYRVTY 1757
              ++V   N +G     V   V ++  P    +   DV  + + I+W+ P+       + Y
Sbjct: 11085 QITV--SNAAGSKTVAVHLTVLDVPGPPTGPINILDVTPEHMTISWQPPKDDGGSPVINY 11142

Query: 1758  -SSPEDGIHELFPAPDGEEDTAELQ--GLRPGSEYTVSV-----VALHDDMESQPLIGTQ 1809
                 +D   + +          +L+   L+ G EY   V     + +   ++S P +   
Sbjct: 11143 IVEKQDTRKDTWGVVSSGSSKTKLKIPHLQKGCEYVFRVRAENKIGVGPPLDSTPTVAKH 11202

Query: 1810  STAIPAPTDLK-FTQVTPTSLSAQWTPPNVQ----LTGYRVRVTPKEKTGPMKEINLAPD 1864
               + P+P      T +T  + +  WT P       +TGY +    +E TG    +N  P 
Sbjct: 11203 KFSPPSPPGKPVVTDITENAATVSWTLPKSDGGSPITGYYME--RREVTGKWVRVNKTPI 11260

Query: 1865  SS-SVVVSGLMVATKYEVSVYALKDTLTSRPAQG-----VVTTLENVSPPRRARVTDATE 1918
             +     V+GL     YE  V+A      S+P+           ++   PP   ++ D + 
Sbjct: 11261 ADLKFRVTGLYEGNTYEFRVFAENLAGLSKPSPSSDPIKACRPIKPPGPPINPKLKDKSR 11320

Query: 1919  TTITISWRTKT-----ETITGFQVDAVPANGQTPIQRTIKPDV---RSYTITGLQPGTDY 1970
              T  + W TK        I G+ V+     G     R  K ++    ++ + GL  G +Y
Sbjct: 11321 ETADLVW-TKPLSDGGSPILGYVVEC-QKPGTAQWNRINKDELIRQCAFRVPGLIEGNEY 11378

Query: 1971  KIYLYTLNDNARSSP 1985
             +  +   N      P
Sbjct: 11379 RFRIKAANIVGEGEP 11393



 Score =  106 bits (265), Expect = 2e-22
 Identities = 320/1538 (20%), Positives = 543/1538 (35%), Gaps = 226/1538 (14%)

Query: 702   TSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSW----VSASDTVSGFRVEYELS 757
             T  P  S  V  +T    P       VT+++     V W         +++G+ +E    
Sbjct: 11881 TGPPTESKPVIAKTKYDKPGRPDPPEVTKVSKEEMTVVWNPPEYDGGKSITGYFLE---K 11937

Query: 758   EEGDEPQYLDLPSTATS---VNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDA- 813
             +E    +++ +  +A     + + +LLP  +Y   V   +E G     L +    A D  
Sbjct: 11938 KEKHSTRWVPVNKSAIPERRMKVQNLLPDHEYQFRVKAENEIGIGEPSLPSRPVVAKDPI 11997

Query: 814   --PPDPTVDQVDDT---SIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANS 864
               P  PT  +V DT   SI + W +P     API GY +   P +  +S +        +
Sbjct: 11998 EPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAPIIGYVVEMRPKIADASPDEGWKRCNAA 12057

Query: 865   VTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGT------------------PRSDT 906
               L      V+   T+ +++ENQE    V  Q   G                   P  D 
Sbjct: 12058 AQL------VRKEFTVTSLDENQEYEFRVCAQNQVGIGRPAELKEAIKPKEILEPPEIDL 12111

Query: 907   VPSPRDLQFVEV-TDVKV-TIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEV 964
               S R L  V     +++  I+   P   VT  +V +  V      GQ   +    F  +
Sbjct: 12112 DASMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVV---RKGQVDLVDTMAFLVI 12168

Query: 965   TGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAP-TNLQFVNETDSTVLVRWTPPR-- 1021
                +   +  + +  V+   E       +      P ++L+  + T ++  V W PP   
Sbjct: 12169 PNSTRDDSGKYSLTLVNPAGEKAVFVNVRVLDTPGPVSDLKVSDVTKTSCHVSWAPPEND 12228

Query: 1022  --AQITGYRLTVGLTRRGQPRQYNVGPSVSK--YPLRNLQPASEYTVSLVAIKGNQESPK 1077
               +Q+T Y   V      +     V P V K  + + NL P +EY   + A+  N+  P 
Sbjct: 12229 GGSQVTHY--IVEKREADRKTWSTVTPEVKKTSFHVTNLVPGNEYYFRVTAV--NEYGPG 12284

Query: 1078  ATG-----VFTTLQPGSSIPPYNTEVTETT---IVITWTPAPRIG-FKLG--VRPSQGGE 1126
                     V  +       PP   EVTE T     + W P  R G  K+   +   +  E
Sbjct: 12285 VPTDVPKPVLASDPLSEPDPPRKLEVTEMTKNSATLAWLPPLRDGGAKIDGYITSYREEE 12344

Query: 1127  APREVTSDSG-----SIVVSGLTPGVEYVYTI---QVLRDGQERDAPIVNKVVTPLSPPT 1178
              P +  ++       S+VV+GL  G +Y + +     +     R+A  V +    L PP 
Sbjct: 12345 QPADRWTEYSVVKDLSLVVTGLKEGKKYKFRVAARNAVGVSLPREAEGVYEAKEQLLPPK 12404

Query: 1179  NL-----------------HLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSL 1221
              L                 H+   P     T  W++     +T   +     +      +
Sbjct: 12405 ILMPEQITIKAGKKLRIEAHVYGKPHP---TCKWKKGEDEVVTSSHLAVHKADSSSILII 12461

Query: 1222  EEVVHADQS--SCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPEVPQLTDLSFVDIT 1279
             ++V   D    S T +N S               K  V + D   P  P   D+S  DI 
Sbjct: 12462 KDVTRKDSGYYSLTAENSSG----------TDTQKIKVVVMDAPGPPQPPF-DIS--DID 12508

Query: 1280  DSSIGLRW-TPLNS--STIIGYRITV--VAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDY 1334
               +  L W  PL    S I  Y +    V+ G+ +        +S     V  L PG +Y
Sbjct: 12509 ADACSLSWHIPLEDGGSNITNYIVEKCDVSRGDWVTALASVTKTSC---RVGKLIPGQEY 12565

Query: 1335  DISVITLINGGESAPTTLTQQTAVPP------PTDLRFTNIGPDTMRVTWAPPPSIDLTN 1388
                V      G S P T  +  A  P      P + R T +  D + V W  P S D  +
Sbjct: 12566 IFRVRAENRFGISEPLTSPKMVAQFPFGVPSEPKNARVTKVNKDCIFVAWDRPDS-DGGS 12624

Query: 1389  FLVRYSPVKNEEDVAELSISPSDNAVVLTN-----LLPGTEYVVSVSSVYEQHESTPLRG 1443
              ++ Y  ++ +E  + L +  +D  V  T      L+ G EY   + ++ +   S P + 
Sbjct: 12625 PIIGYL-IERKERNSLLWVKANDTLVRSTEYPCAGLVEGLEYSFRIYALNKAGSSPPSKP 12683

Query: 1444  RQ----KTGLDSPTGIDFSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPRED 1495
              +    +  +D P   +  D+T ++ ++ W  P+    + I GY +           R +
Sbjct: 12684 TEYVTARMPVDPPGKPEVIDVTKSTVSLIWARPKHDGGSKIIGYFVEACKLPGDKWVRCN 12743

Query: 1496  RVPHS--RNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTV---SDVPRDLEVVAA 1550
               PH   +   T T L    +Y    +A      SP             +VP  +++  A
Sbjct: 12744 TAPHQIPQEEYTATGLEEKAQYQFRAIARTAVNISPPSEPSDPVTILAENVPPRIDLSVA 12803

Query: 1551  TPTSLLIS------WDAPAVTVRYYRITYGETGGN-SPVQEFTVPGSKSTATIS----GL 1599
               + L +        DA         +++ + G    P +   +   ++  T+       
Sbjct: 12804 MKSLLTVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNR 12863

Query: 1600  KPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLP---- 1655
             K   DYTIT         S + S  I +    +   P+ +++  +  +   + W P    
Sbjct: 12864 KDSGDYTITA-----ENSSGSKSATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLED 12918

Query: 1656  SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPL 1715
               S +T Y V     + P   +     P  T  ++E L    EY   + A+N  G   P+
Sbjct: 12919 GGSEITNYIVDKRETSRPNWAQVSATVPI-TSCSVEKLIEGHEYQFRICAENKYGVGDPV 12977

Query: 1716  -VQTAVT-NIDRPKGLA----FTDVDVDSIKIAWESPQGQ----VSRYRVTYSSPEDGIH 1765
               + A+  N   P G       +++  D + ++W+ P       ++ Y +     +    
Sbjct: 12978 FTEPAIAKNPYDPPGRCDPPVISNITKDHMTVSWKPPADDGGSPITGYLLEKRETQAVNW 13037

Query: 1766  ELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAI------PAPTDL 1819
                      E T +  GL+ G+EY   V A++     +P   +++         P P   
Sbjct: 13038 TKVNRKPIIERTLKATGLQEGTEYEFRVTAINKAGPGKPSDASKAAYARDPQYPPGPPAF 13097

Query: 1820  -KFTQVTPTSLSAQWTPPNVQ----LTGYRVRVTPKEKTGPMKEINLAPD--SSSVVVSG 1872
              K    T +S+S  W  P       + GY V V   +    ++  NL  +   +   V+G
Sbjct: 13098 PKVYDTTRSSVSLSWGKPAYDGGSPIIGYLVEVKRADSDNWVR-CNLPQNLQKTRFEVTG 13156

Query: 1873  LMVATKYEVSVYALKDTLTSRPAQ--GVVTTLENVSPPRRARVTDATETTITISWRTKTE 1930
             LM  T+Y+  VYA+     S P+         + + PP      D  +T I  +  T   
Sbjct: 13157 LMEDTQYQFRVYAVNKIGYSDPSDVPDKHYPKDILIPPEGELDADLRKTLILRAGVTMRL 13216

Query: 1931  TITGFQVDAVPANGQTPIQRT-IKPDVRSYTITGLQ-PGTDYKIYLYTLNDN-------- 1980
                      VP  G+ P + T  KP+V      GL    TD+  +L   N N        
Sbjct: 13217 --------YVPVKGRPPPKITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKYI 13268

Query: 1981  --------ARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPP----RARITGYIIKY 2028
                      +   +V+        P N+     + +S  V+W+PP     + I  Y+++ 
Sbjct: 13269 LTLENSCGKKEYTIVVKVLDTPGPPVNVTVKEISKDSAYVTWEPPIIDGGSPIINYVVQK 13328

Query: 2029  EKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIA 2066
                       V       T   +  LE G  Y   V A
Sbjct: 13329 RDAERKSWSTV-TTECSKTSFRVANLEEGKSYFFRVFA 13365



 Score =  102 bits (255), Expect = 3e-21
 Identities = 297/1362 (21%), Positives = 483/1362 (35%), Gaps = 240/1362 (17%)

Query: 908   PSP-RDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTG 966
             P P R+L+ V+V+  + T+ W PPE    G  +     N   E  +   +  +T++  T 
Sbjct: 11800 PGPVRNLKIVDVSSDRCTVCWDPPEDD-GGCEIQ----NYILEKCETKRMVWSTYS-ATV 11853

Query: 967   LSPGVT---------YYFKVFAVSH-----GRESKPLTAQQTTKLDAP-----TNLQFVN 1007
             L+PG T         Y F+V A +        ESKP+ A+  TK D P       +  V+
Sbjct: 11854 LTPGTTVTRLIEGNEYIFRVRAENKIGTGPPTESKPVIAK--TKYDKPGRPDPPEVTKVS 11911

Query: 1008  ETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSV---SKYPLRNLQPAS 1060
             + + TV+  W PP       ITGY L      +   R   V  S     +  ++NL P  
Sbjct: 11912 KEEMTVV--WNPPEYDGGKSITGYFLEK--KEKHSTRWVPVNKSAIPERRMKVQNLLPDH 11967

Query: 1061  EYTVSLVAIK----GNQESPKATGVFTT-LQPGSSIPPYNTEVTETT---IVITWTP--- 1109
             EY   + A      G    P    V    ++P    PP N  V +TT   I + W     
Sbjct: 11968 EYQFRVKAENEIGIGEPSLPSRPVVAKDPIEPPG--PPTNFRVVDTTKHSITLGWGKPVY 12025

Query: 1110  ---APRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPI 1166
                AP IG+ + +RP     +P     D G    +     V   +T+  L + QE +  +
Sbjct: 12026 DGGAPIIGYVVEMRPKIADASP-----DEGWKRCNAAAQLVRKEFTVTSLDENQEYEFRV 12080

Query: 1167  VNKVVTPLSPPTNLHLEANP-----------DTGVLTVSWERSTTPD--ITGYRITTTPT 1213
               +    +  P  L     P           D  +  +   R+  P       R    P 
Sbjct: 12081 CAQNQVGIGRPAELKEAIKPKEILEPPEIDLDASMRKLVIVRAGCPIRLFAIVRGRPAPK 12140

Query: 1214  NGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDD-------------KESVPIS 1260
                +   ++ VV   Q      +L   + + V   + +DD             +++V ++
Sbjct: 12141 VTWRKVGIDNVVRKGQV-----DLVDTMAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFVN 12195

Query: 1261  DTIIPEVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGYRIT--VVAAGEGIPIFEDFVDS 1318
               ++     ++DL   D+T +S  + W P  +    G ++T  +V   E        V  
Sbjct: 12196 VRVLDTPGPVSDLKVSDVTKTSCHVSWAPPENDG--GSQVTHYIVEKREADRKTWSTVTP 12253

Query: 1319  SVGY--YTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAVP-------PPTDLRFTNI 1369
              V    + VT L PG +Y   V  +   G   PT + +            PP  L  T +
Sbjct: 12254 EVKKTSFHVTNLVPGNEYYFRVTAVNEYGPGVPTDVPKPVLASDPLSEPDPPRKLEVTEM 12313

Query: 1370  GPDTMRVTWAPP---PSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYV 1426
               ++  + W PP       +  ++  Y   +   D         D ++V+T L  G +Y 
Sbjct: 12314 TKNSATLAWLPPLRDGGAKIDGYITSYREEEQPADRWTEYSVVKDLSLVVTGLKEGKKYK 12373

Query: 1427  VSVSSVYEQHESTPLRGR----QKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIR 1482
               V++      S P         K  L  P  +    IT  +             G ++R
Sbjct: 12374 FRVAARNAVGVSLPREAEGVYEAKEQLLPPKILMPEQITIKA-------------GKKLR 12420

Query: 1483  HHPEHFSGRPR--------EDRV----------PHSRNSITLTNLTPGTEYVVSIVALNG 1524
                 H  G+P         ED V            S + + + ++T       S+ A N 
Sbjct: 12421 IEA-HVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGYYSLTAENS 12479

Query: 1525  R----EESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAP----AVTVRYYRITYGET 1576
                  ++  +++         P D+  + A   SL  SW  P       +  Y +   + 
Sbjct: 12480 SGTDTQKIKVVVMDAPGPPQPPFDISDIDADACSL--SWHIPLEDGGSNITNYIVEKCDV 12537

Query: 1577  GGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDS-PASSKPISINYRTEI-D 1634
                  V       +K++  +  L PG +Y   V A    G S P +S  +   +   +  
Sbjct: 12538 SRGDWVTALASV-TKTSCRVGKLIPGQEYIFRVRAENRFGISEPLTSPKMVAQFPFGVPS 12596

Query: 1635  KPSQMQVTDVQDNSISVKW-LPSS---SPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTI 1690
             +P   +VT V  + I V W  P S   SP+ GY +    +N     K        TE   
Sbjct: 12597 EPKNARVTKVNKDCIFVAWDRPDSDGGSPIIGYLIERKERNSLLWVKANDTLVRSTEYPC 12656

Query: 1691  EGLQPTVEYVVSVYAQNPSGESQPLVQTAVTN----IDRPKGLAFTDVDVDSIKIAWESP 1746
              GL   +EY   +YA N +G S P   T        +D P      DV   ++ + W  P
Sbjct: 12657 AGLVEGLEYSFRIYALNKAGSSPPSKPTEYVTARMPVDPPGKPEVIDVTKSTVSLIWARP 12716

Query: 1747  QGQVSRYRVTY-----SSPEDGIHELFPAPDG---EEDTAELQGLRPGSEYTVSVVALHD 1798
             +       + Y       P D       AP     EE TA   GL   ++Y    +A   
Sbjct: 12717 KHDGGSKIIGYFVEACKLPGDKWVRCNTAPHQIPQEEYTAT--GLEEKAQYQFRAIARTA 12774

Query: 1799  DMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLT-GYRVRVTPKEKTG--- 1854
                S P           P+D       P ++ A+  PP + L+   +  +T K  T    
Sbjct: 12775 VNISPP---------SEPSD-------PVTILAENVPPRIDLSVAMKSLLTVKAGTNVCL 12818

Query: 1855  -------PMKEINLAPDSSSVV-VSGLMVATKYEVSVYAL-----KD----TLTSRPAQG 1897
                    PM  ++   D + +    G+ +A +  +    L     KD    T+T+  + G
Sbjct: 12819 DATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTITAENSSG 12878

Query: 1898  V------VTTLENVSPPRRARVTDATETTITISWRTKTET----ITGFQVDAVPANGQTP 1947
                    +  L+   PP   ++         +SW    E     IT + VD    +    
Sbjct: 12879 SKSATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYIVDKRETSRPNW 12938

Query: 1948  IQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTA---IDAPSNLR--- 2001
              Q +    + S ++  L  G +Y+  +   N      PV  + + A    D P       
Sbjct: 12939 AQVSATVPITSCSVEKLIEGHEYQFRICAENKYGVGDPVFTEPAIAKNPYDPPGRCDPPV 12998

Query: 2002  FLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREVVPRPRPGVTEATI--TGLE 2055
                 T + + VSW+PP     + ITGY++  EK  +         R  + E T+  TGL+
Sbjct: 12999 ISNITKDHMTVSWKPPADDGGSPITGYLL--EKRETQAVNWTKVNRKPIIERTLKATGLQ 13056

Query: 2056  PGTEYTIYVIALKNNQKSEPLIGRKKTVQKTPFVTHPGYDTG 2097
              GTEY   V A+    K+ P  G+     K  +   P Y  G
Sbjct: 13057 EGTEYEFRVTAI---NKAGP--GKPSDASKAAYARDPQYPPG 13093



 Score =  102 bits (255), Expect = 3e-21
 Identities = 274/1373 (19%), Positives = 474/1373 (34%), Gaps = 187/1373 (13%)

Query: 766   LDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDT 825
             +DL  T   + IP+         ++  ++  GE+++ ++      P    D  V  V  T
Sbjct: 12157 VDLVDTMAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFVNVRVLDTPGPVSDLKVSDVTKT 12216

Query: 826   SIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETAN-SVTLSDLQPGVQYNITI 880
             S  V W+ P+    + +T Y IV     +  +     PE    S  +++L PG +Y   +
Sbjct: 12217 SCHVSWAPPENDGGSQVTHY-IVEKREADRKTWSTVTPEVKKTSFHVTNLVPGNEYYFRV 12275

Query: 881   YAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTG 936
              AV E     P  + +    +        PR L+  E+T    T+ W PP     + + G
Sbjct: 12276 TAVNEYGPGVPTDVPKPVLASDPLSEPDPPRKLEVTEMTKNSATLAWLPPLRDGGAKIDG 12335

Query: 937   YRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTK 996
             Y         P +      + ++    VTGL  G  Y F+V             A+    
Sbjct: 12336 YITSYREEEQPADRWTEYSVVKDLSLVVTGLKEGKKYKFRV------------AARNAVG 12383

Query: 997   LDAPTNLQFVNETDSTVLVRWTPPR----AQIT---GYRLTVGLTRRGQPR--------- 1040
             +  P   + V E    +L    PP+     QIT   G +L +     G+P          
Sbjct: 12384 VSLPREAEGVYEAKEQLL----PPKILMPEQITIKAGKKLRIEAHVYGKPHPTCKWKKGE 12439

Query: 1041  ---------QYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSI 1091
                        +   S S   ++++        SL A   +    +   V     PG   
Sbjct: 12440 DEVVTSSHLAVHKADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPGPPQ 12499

Query: 1092  PPYN-TEVTETTIVITW-TPAPRIGFKL------GVRPSQGGEAPREVTSDSGSIVVSGL 1143
             PP++ +++      ++W  P    G  +          S+G       +    S  V  L
Sbjct: 12500 PPFDISDIDADACSLSWHIPLEDGGSNITNYIVEKCDVSRGDWVTALASVTKTSCRVGKL 12559

Query: 1144  TPGVEYVYTIQVLRDGQERDAPIVNKVV------TPLSPPTNLHLEANPDTGVLTVSWER 1197
              PG EY++ ++        +     K+V       P  P      + N D   + V+W+R
Sbjct: 12560 IPGQEYIFRVRAENRFGISEPLTSPKMVAQFPFGVPSEPKNARVTKVNKD--CIFVAWDR 12617

Query: 1198  STT---PDITGYRITTTPTNGQQG-NSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDD 1253
               +     I GY I     N      + + +V + +  C    L  GLEY+  +Y +   
Sbjct: 12618 PDSDGGSPIIGYLIERKERNSLLWVKANDTLVRSTEYPCA--GLVEGLEYSFRIYALNKA 12675

Query: 1254  KESVPISDTIIPEVPQLTD----LSFVDITDSSIGLRWTPL---NSSTIIGYRITVV--- 1303
               S P   T         D       +D+T S++ L W        S IIGY +      
Sbjct: 12676 GSSPPSKPTEYVTARMPVDPPGKPEVIDVTKSTVSLIWARPKHDGGSKIIGYFVEACKLP 12735

Query: 1304  --------AAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVI--TLIN----GGESAP 1349
                      A   IP  E         YT TGLE    Y    I  T +N       S P
Sbjct: 12736 GDKWVRCNTAPHQIPQEE---------YTATGLEEKAQYQFRAIARTAVNISPPSEPSDP 12786

Query: 1350  TTLTQQTAVPPPTDLRF-----------TNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKN 1398
              T+  +  VPP  DL             TN+  D   V   P P++          P + 
Sbjct: 12787 VTILAEN-VPPRIDLSVAMKSLLTVKAGTNVCLDA-TVFGKPMPTVSWKKDGTLLKPAEG 12844

Query: 1399  EEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHEST-PLRGRQKTGLDSPTGIDF 1457
              +   + ++   +  +   N     +Y ++  +      +T  L+   K G   P  +  
Sbjct: 12845 IKMAMQRNLCTLE--LFSVNRKDSGDYTITAENSSGSKSATIKLKVLDKPG--PPASVKI 12900

Query: 1458  SDITANSFTVHWIAP----RATITGYRIRHHPEHFSGRPREDRVPHS--RNSITLTNLTP 1511
             + + ++   + W  P     + IT Y +    +  + RP   +V  +    S ++  L  
Sbjct: 12901 NKMYSDRAMLSWEPPLEDGGSEITNYIV---DKRETSRPNWAQVSATVPITSCSVEKLIE 12957

Query: 1512  GTEYVVSIVALNGREESPLLIGQQSTVS---DVPR--DLEVVA-ATPTSLLISWDAPA-- 1563
             G EY   I A N       +  + +      D P   D  V++  T   + +SW  PA  
Sbjct: 12958 GHEYQFRICAENKYGVGDPVFTEPAIAKNPYDPPGRCDPPVISNITKDHMTVSWKPPADD 13017

Query: 1564  --VTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRG---DS 1618
                 +  Y +   ET   +  +    P  + T   +GL+ G +Y   V A+   G    S
Sbjct: 13018 GGSPITGYLLEKRETQAVNWTKVNRKPIIERTLKATGLQEGTEYEFRVTAINKAGPGKPS 13077

Query: 1619  PASSKPISINYRTEIDKPSQMQVTDVQDNSISVKW----LPSSSPVTGYRVTTTPKNGPG 1674
              AS    + + +     P+  +V D   +S+S+ W        SP+ GY V     +   
Sbjct: 13078 DASKAAYARDPQYPPGPPAFPKVYDTTRSSVSLSWGKPAYDGGSPIIGYLVEVKRADSDN 13137

Query: 1675  PTKTK-TAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKGLAFT- 1732
               +        +T   + GL    +Y   VYA N  G S P   + V +   PK +    
Sbjct: 13138 WVRCNLPQNLQKTRFEVTGLMEDTQYQFRVYAVNKIGYSDP---SDVPDKHYPKDILIPP 13194

Query: 1733  --DVDVDSIKIAWESPQGQVSRY---------RVTYSSPEDGIHELFPAPDGEED----- 1776
               ++D D  K         +  Y         ++T+S P   + +         D     
Sbjct: 13195 EGELDADLRKTLILRAGVTMRLYVPVKGRPPPKITWSKPNVNLRDRIGLDIKSTDFDTFL 13254

Query: 1777  TAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPP 1836
               E        +Y +++       E   ++    T  P P ++   +++  S    W PP
Sbjct: 13255 RCENVNKYDAGKYILTLENSCGKKEYTIVVKVLDTPGP-PVNVTVKEISKDSAYVTWEPP 13313

Query: 1837  NVQ----LTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTS 1892
              +     +  Y V+    E+      +      +S  V+ L     Y   V+A  +    
Sbjct: 13314 IIDGGSPIINYVVQKRDAERKS-WSTVTTECSKTSFRVANLEEGKSYFFRVFAENEYGIG 13372

Query: 1893  RPAQ--GVVTTLENVSPPRRARVTDATETTITISWRTK----TETITGFQVDAVPANGQT 1946
              P +    V   +   P    +V   ++++ +I W+         I G+ VD +    + 
Sbjct: 13373 DPGETRDAVKASQTPGPVVDLKVRSVSKSSCSIGWKKPHSDGGSRIIGYVVDFLTEENKW 13432

Query: 1947  PIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSP--VVIDASTAIDAP 1997
               QR +K     Y+   L  G +Y   +   N+N   +P  + + A   + AP
Sbjct: 13433 --QRVMKSLSLQYSAKDLTEGKEYTFRVSAENENGEGTPSEITVVARDDVVAP 13483



 Score =  102 bits (255), Expect = 3e-21
 Identities = 328/1625 (20%), Positives = 588/1625 (36%), Gaps = 231/1625 (14%)

Query: 609   SGPVEVFITETPSQ----------PNSHPIQWNAPQ---PSHISKYILRWRPKNSVGRWK 655
             SG V V + +TP             +S  + W+ P     S I+ YI+  R       + 
Sbjct: 14360 SGFVNVRVLDTPGPVLNLRPTDITKDSVTLHWDLPLIDGGSRITNYIVEKREATRKS-YS 14418

Query: 656   EATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGET 715
              AT   H  +Y + GL  G  Y  ++++  +YG  E        T T+ PV ++      
Sbjct: 14419 TATTKCHKCTYKVTGLSEGCEYFFRVMAENEYGIGE-------PTETTEPVKASE----- 14466

Query: 716   TPFSPLVATSESVTEITASSFVVSWVS----ASDTVSGFRVEYELSEEGDEPQYLDLPST 771
                +P    S ++ +IT S+  ++W          ++G+ +E +  +  D+  ++     
Sbjct: 14467 ---APSPPDSLNIMDITKSTVSLAWPKPKHDGGSKITGYVIEAQ-RKGSDQWTHITTVKG 14522

Query: 772   ATSVNIPDLLPGRKYIVNVYQISEDG-----EQSLILSTSQTTAPDAPPDPTVDQV---- 822
                V + +L  G +Y   V  ++  G     E   ++   QT  P+        ++    
Sbjct: 14523 LECV-VRNLTEGEEYTFQVMAVNSAGRSAPRESRPVIVKEQTMLPELDLRGIYQKLVIAK 14581

Query: 823   --DDTSIVVR-WSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNIT 879
               D+  + +    RP+  +T  +      +   +  +N   TA S T+ ++   V+ +  
Sbjct: 14582 AGDNIKVEIPVLGRPKPTVTWKK---GDQILKQTQRVNFETTATS-TILNINECVRSDSG 14637

Query: 880   IYAVEENQESTPV--VIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPES----A 933
              Y +        V  VI  +    P   T P    ++F EV+   VT  W PPE+     
Sbjct: 14638 PYPLTARNIVGEVGDVITIQVHDIPGPPTGP----IKFDEVSSDFVTFSWDPPENDGGVP 14693

Query: 934   VTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKV-----FAVSHGRESKP 988
             ++ Y V++   +          + R T+ + T L+ G+ Y F+V     + V  G  S  
Sbjct: 14694 ISNYVVEMRQTDSTTWVELATTVIRTTY-KATRLTTGLEYQFRVKAQNRYGVGPGITSAC 14752

Query: 989   LTAQQTTKLDAPTNL-QFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPS 1047
             + A    K+  P    Q    T  ++ + W  P +   G    +G     + R   +  +
Sbjct: 14753 IVANYPFKVPGPPGTPQVTAVTKDSMTISWHEPLSD--GGSPILGYHVERKERNGILWQT 14810

Query: 1048  VSK-------YPLRNLQPASEYTVSLVA--IKGNQESPKATGVFTTLQP----GSSIPPY 1094
             VSK       +    L     Y   ++A  + G  +  K +     L P    G  +P  
Sbjct: 14811 VSKALVPGNIFKSSGLTDGIAYEFRVIAENMAGKSKPSKPSEPMLALDPIDPPGKPVP-- 14868

Query: 1095  NTEVTETTIVITWT-PAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTI 1153
                +T  T+ + W  P    GFK+     +  + P      +G  + +  +  +E  +T+
Sbjct: 14869 -LNITRHTVTLKWAKPEYTGGFKITSYIVEKRDLP------NGRWLKANFSNILENEFTV 14921

Query: 1154  QVLRDGQERDAPIVNK----VVTPLSPPTNL-----HLEANP--------DTGVLTVSWE 1196
               L +    +  ++ K     ++P S P++       +EA          DT +L     
Sbjct: 14922 SGLTEDAAYEFRVIAKNAAGAISPPSEPSDAITCRDDVEAPKIKVDVKFKDTVILKAGEA 14981

Query: 1197  RSTTPDITGYRITTTPTNGQQGNSLE-------------------EVVHADQSSCTFDNL 1237
                  D++G R   T    + G  LE                   +    D  + T    
Sbjct: 14982 FRLEADVSG-RPPPTMEWSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDSGAYTLTAT 15040

Query: 1238  SPGLEYNVSVYTVKDDKESVPISDTIIPEVPQLTDLSFVDITDSSIGLRWTPL--NSSTI 1295
             +PG  +   ++ VK      P      PE P    L+  ++T     L W P   +    
Sbjct: 15041 NPG-GFAKHIFNVKVLDRPGP------PEGP----LAVTEVTSEKCVLSWFPPLDDGGAK 15089

Query: 1296  IGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGG-----ESAPT 1350
             I + I        +       +  V    VT L  G +Y   V+ +   G     ES P 
Sbjct: 15090 IDHYIVQKRETSRLAWTNVASEVQVTKLKVTKLLKGNEYIFRVMAVNKYGVGEPLESEPV 15149

Query: 1351  TLTQQTAVP-PPTDLRFTNIGPDTMRVTWAPPPS---IDLTNFLVRYSPVKNEEDVAELS 1406
                     P PP +   T I  D+M V W  P S    ++ N++V       +  +    
Sbjct: 15150 LAVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDSDGGSEIINYIVERRDKAGQRWIKCNK 15209

Query: 1407  ISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTP------LRGRQKTGLDSPTGID-FSD 1459
              + +D    ++ L  G EY   + +      S P       +         P G     D
Sbjct: 15210 KTLTDLRYKVSGLTEGHEYEFRIMAENAAGISAPSPTSPFYKACDTVFKPGPPGNPRVLD 15269

Query: 1460  ITANSFTVHWIAP----RATITGYRIRHH-PEHFSGRPREDRVPHSRNSITLTNLTPGTE 1514
              + +S ++ W  P     + ITGY +    PE    +           S T+T LT   E
Sbjct: 15270 TSRSSISIAWNKPIYDGGSEITGYMVEIALPEEDEWQIVTPPAGLKATSYTITGLTENQE 15329

Query: 1515  YVVSIVALNG-------------REESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDA 1561
             Y + I A+N              + E  +L  +    +D+ + + + A     L +    
Sbjct: 15330 YKIRIYAMNSEGLGEPALVPGTPKAEDRMLPPEIELDADLRKVVTIRACCTLRLFVPIKG 15389

Query: 1562  -PAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPA 1620
              PA  V++ R  +GE+   + ++      S S+ T+  +     +    Y +T    S +
Sbjct: 15390 RPAPEVKWAR-DHGESLDKASIE------STSSYTLLIVGNVNRFDSGKYILTVENSSGS 15442

Query: 1621  SSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLP----SSSPVTGYRVTTTPKNGPGPT 1676
              S  +++        P  ++V +V   S+++ W P      S +  Y V          +
Sbjct: 15443 KSAFVNVRVLDTPGPPQDLKVKEVTKTSVTLTWDPPLLDGGSKIKNYIVEKRESTRKAYS 15502

Query: 1677  KTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPL-VQTAVTNIDRPKG---LAFT 1732
                T    +T   ++ LQ    Y   V A+N  G   P     +V   +RP     +   
Sbjct: 15503 TVAT-NCHKTSWKVDQLQEGCSYYFRVLAENEYGIGLPAETAESVKASERPLPPGKITLM 15561

Query: 1733  DVDVDSIKIAWESPQGQVSRYRVTY--SSPEDGIHELFPAPDGEEDTAELQGLRPGSEYT 1790
             DV  +S+ ++WE P+       + Y       G  +       +   A + GL  G EY+
Sbjct: 15562 DVTRNSVSLSWEKPEHDGGSRILGYIVEMQTKGSDKWATCATVKVTEATITGLIQGEEYS 15621

Query: 1791  VSVVALHDDMESQPL-----IGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRV 1845
               V A ++   S P      +  +   IP    L F   T T L+ +    +V   G   
Sbjct: 15622 FRVSAQNEKGISDPRQLSVPVIAKDLVIPPAFKLLFN--TFTVLAGEDLKVDVPFIGRPT 15679

Query: 1846  -RVTPKEKTGPMKEINLAPDSSSVVVSGLMV--ATKYEVSVYALKDTLTSRPAQGV---- 1898
               VT  +   P+K+       S+   S L +  A + +V  Y +K  LT+   + +    
Sbjct: 15680 PAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVK--LTNSAGEAIETLN 15737

Query: 1899  VTTLENVSPPR-RARVTDATETTITISWRTKT----ETITGFQVDAVPANGQTPIQRTIK 1953
             V  L+   PP    ++ + T  +IT+SW         +I  + V+    +  T   + + 
Sbjct: 15738 VIVLDKPGPPTGPVKMDEVTADSITLSWGPPKYDGGSSINNYIVE--KRDTSTTTWQIVS 15795

Query: 1954  PDVRSYTITG--LQPGTDYKIYL-----YTLNDNARSSPVVIDASTAIDAPSNLRFLA-T 2005
               V   TI    L+ G +Y+  +     Y  +    S P V      +  P     +  +
Sbjct: 15796 ATVARTTIKACRLKTGCEYQFRIAAENRYGKSTYLNSEPTVAQYPFKVPGPPGTPVVTLS 15855

Query: 2006  TPNSLLVSWQPP----RARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYT 2061
             + +S+ V W  P     +R+ GY ++ ++  S     + +     T+   TGLE G EY 
Sbjct: 15856 SRDSMEVQWNEPISDGGSRVIGYHLERKERNSILWVKLNKTPIPQTKFKTTGLEEGVEYE 15915

Query: 2062  IYVIA 2066
               V A
Sbjct: 15916 FRVSA 15920



 Score =  102 bits (255), Expect = 3e-21
 Identities = 306/1554 (19%), Positives = 528/1554 (33%), Gaps = 201/1554 (12%)

Query: 610   GPVEVFITETPSQPNSHPIQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSY 666
             GP E  +  T        + WN P     ++IS YI+  R  + +  W + +      +Y
Sbjct: 18306 GPPEGPLKVTGVTAEKCYLAWNPPLQDGGANISHYIIEKRETSRLS-WTQVSTEVQALNY 18364

Query: 667   TIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSE 726
              +  L PG  Y  +++++ +YG  E             P+ S  VT       P   ++ 
Sbjct: 18365 KVTKLLPGNEYIFRVMAVNKYGIGE-------------PLESGPVTACNPYKPPGPPSTP 18411

Query: 727   SVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDE-----PQYLDLPSTATSVNIPDLL 781
              V+ IT  S VV+W    D   G  +E  + E+ D+      +      T   + +  L 
Sbjct: 18412 EVSAITKDSMVVTWARPVDD-GGTEIEGYILEKRDKEGVRWTKCNKKTLTDLRLRVTGLT 18470

Query: 782   PGRKY-----IVNVYQISEDGEQSLILSTSQTTAPDAPP-DPTVDQVDDTSIVVRWSRP- 834
              G  Y       N   + E  E S+         P  PP +P V     +S+ + WS+P 
Sbjct: 18471 EGHSYEFRVAAENAAGVGEPSEPSVFYRACDALYPPGPPSNPKVTDTSRSSVSLAWSKPI 18530

Query: 835   ---QAPITGYRIVYSPSVEGSSTELNLPE--TANSVTLSDLQPGVQYNITIYAVEENQES 889
                 AP+ GY +    +     T    P        T++ L+   +YN  I A+      
Sbjct: 18531 YDGGAPVKGYVVEVKEAAADEWTTCTPPTGLQGKQFTVTKLKENTEYNFRICAINSEGVG 18590

Query: 890   TPVVIQQETTGTPRSD--TVPSPRDLQFVEVTDVKVTI-----MWTPPESAVTGYRVDVI 942
              P  +        R +   +    DL+ V V     T+     +   PE  V   + + I
Sbjct: 18591 EPATLPGSVVAQERIEPPEIELDADLRKVVVLRASATLRLFVTIKGRPEPEVKWEKAEGI 18650

Query: 943   PVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTN 1002
               +   +       +      VT    G   Y      + G ++  +  +      AP N
Sbjct: 18651 LTD-RAQIEVTSSFTMLVIDNVTRFDSG--RYNLTLENNSGSKTAFVNVRVLDSPSAPVN 18707

Query: 1003  LQFVNETDSTVLVRWTPP----RAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQP 1058
             L        +V + W PP     A+IT Y +    T R          + + + + NLQ 
Sbjct: 18708 LTIREVKKDSVTLSWEPPLIDGGAKITNYIVEKRETTRKAYATITNNCTKTTFRIENLQE 18767

Query: 1059  ASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYN------TEVTETTIVITW-TPAP 1111
                Y   ++A   + E        TT     S PP         +VT  T  I W  P  
Sbjct: 18768 GCSYYFRVLA---SNEYGIGLPAETTEPVKVSEPPLPPGRVTLVDVTRNTATIKWEKPES 18824

Query: 1112  RIGFKLG----VRPSQGGEAPREVTS-DSGSIVVSGLTPGVEYVYTIQVLR-----DGQE 1161
               G K+        ++G E     T   +    +SGLT G EYV+ +  +      D ++
Sbjct: 18825 DGGSKITGYVVEMQTKGSEKWSTCTQVKTLEATISGLTAGEEYVFRVAAVNEKGRSDPRQ 18884

Query: 1162  RDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDIT-GYRITTTPTNGQQGNS 1220
                P++ + +  + P   L            V        D+    R   T    + G +
Sbjct: 18885 LGVPVIARDI-EIKPSVELPFH------TFNVKAREQLKIDVPFKGRPQATVNWRKDGQT 18937

Query: 1221  LEEVVHADQSS---CTFDNLSPGLEYNVSVY--TVKDDKESVPISDTII------PEVPQ 1269
             L+E    + SS    T  ++    + +V  Y   V +   S+ +  TII      P  P 
Sbjct: 18938 LKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSNSAGSITVPITIIVLDRPGPPGPI 18997

Query: 1270  LTDLSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIFEDFVDSSVGYYT--VTG 1327
               D    +++  SI + W P            +V   E        V  +V   +  +  
Sbjct: 18998 RID----EVSCDSITISWNPPEYDGGCQISNYIVEKKETTSTTWHIVSQAVARTSIKIVR 19053

Query: 1328  LEPGIDYDISVITLINGGESAPTTLTQQTA------VPPPTDLRFTNIGPDTMRVTWAPP 1381
             L  G +Y   V      G+S+ +  +   A        PP   +  +    TM VTW  P
Sbjct: 19054 LTTGSEYQFRVCAENRYGKSSYSESSAVVAEYPFSPPGPPGTPKVVHATKSTMLVTWQVP 19113

Query: 1382  PSIDLTNFLVRYSPVKNEEDV---AELSISPSDNAVVLTNLLPGTEY--------VVSVS 1430
              +   +  +  +   K    +       I  +D  + ++ L  G  Y        +  + 
Sbjct: 19114 VNDGGSRVIGYHLEYKERSSILWSKANKILIADTQMKVSGLDEGLMYEYRVYAENIAGIG 19173

Query: 1431  SVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPR----ATITGYRIRHHPE 1486
                +  E  P R       D P   + ++IT  S ++ W  P     A ITGY +    E
Sbjct: 19174 KCSKSCEPVPAR----DPCDPPGQPEVTNITRKSVSLKWSKPHYDGGAKITGYIVERR-E 19228

Query: 1487  HFSGRPREDRVPHSRNS-ITLTNLTPGTEYVVSIVALNGREE--------SPLLIGQQST 1537
                GR  +    + + +   +T LT    Y   + A N  +          P+++     
Sbjct: 19229 LPDGRWLKCNYTNIQETYFEVTELTEDQRYEFRVFARNAADSVSEPSESTGPIIVKDDVE 19288

Query: 1538  VSDVPRDLE----VVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKST 1593
                V  D++    +V      L I+ D     +    I++ + G     +  T   S   
Sbjct: 19289 PPRVMMDVKFRDVIVVKAGEVLKINADIAGRPLPV--ISWAKDGIEIEERARTEIISTDN 19346

Query: 1594  ATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKP----SQMQVTDVQDNSI 1649
              T+  +K  +      Y +T +  + A ++ +++N +  +DKP      +++  +     
Sbjct: 19347 HTLLTVKDCIRRDTGQYVLTLK--NVAGTRSVAVNCKV-LDKPGPPAGPLEINGLTAEKC 19403

Query: 1650  SVKW---LPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQ 1706
             S+ W            Y +    +               T   +  L    EY+  V   
Sbjct: 19404 SLSWGRPQEDGGADIDYYIVEKRETSHLAWTICEGELQMTSCKVTKLLKGNEYIFRVTGV 19463

Query: 1707  NPSGESQPLVQTAVTNID------RPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSP 1760
             N  G  +PL   A+  +D       P  L  T V  +S+ + W  P+         Y   
Sbjct: 19464 NKYGVGEPLESVAIKALDPFTVPSPPTSLEITSVTKESMTLCWSRPESDGGSEISGYIIE 19523

Query: 1761  EDGIHELFPAPDGEEDTAELQ----GLRPGSEYTVSVVA-----LHDDMESQPLIGTQST 1811
                 + L      ++   +L+    GLR G EY   V A     L    E+ PLI  +  
Sbjct: 19524 RREKNSLRWVRVNKKPVYDLRVKSTGLREGCEYEYRVYAENAAGLSLPSETSPLIRAEDP 19583

Query: 1812  A-IPA-PTDLKFTQVTPTSLSAQWTPP----NVQLTGYRVRVTPKEKTGPMKEINLAPDS 1865
               +P+ P+  K      T+++  W  P       +TGY V     + T     I  +   
Sbjct: 19584 VFLPSPPSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEYKKSDDTDWKTSIQ-SLRG 19642

Query: 1866  SSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENV----------SPPRRARVTD 1915
             +   +SGL    +Y   V ++     S P+      +             S  R+  +  
Sbjct: 19643 TEYTISGLTTGAEYVFRVKSVNKVGASDPSDSSDPQIAKEREEEPLFDIDSEMRKTLIVK 19702

Query: 1916  A-TETTITISWRTK-----------TETITGFQVDAVPANGQTPIQRTIKPDVRSYTITG 1963
             A    T+T+ +R +           T+  T   VD   +     I+   + D   YT+T 
Sbjct: 19703 AGASFTMTVPFRGRPVPNVLWSKPDTDLRTRAYVDTTDSRTSLTIENANRNDSGKYTLT- 19761

Query: 1964  LQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPP 2017
             +Q              +A S  +V+        P+N+     T  S ++SW  P
Sbjct: 19762 IQNVL-----------SAASLTLVVKVLDTPGPPTNITVQDVTKESAVLSWDVP 19804



 Score =  100 bits (248), Expect = 2e-20
 Identities = 162/726 (22%), Positives = 275/726 (37%), Gaps = 92/726 (12%)

Query: 1268  PQLTDLSFVDITDSSIGLRWTPLN---SSTIIGYRITVVAAGEG--IPIFEDFVDSSVGY 1322
             P    +   +I  +SI + W P      + + GY +    A     +P+ E    S+   
Sbjct: 23337 PPTGPIKIDEIDATSITISWEPPELDGGAPLSGYVVEQRDAHRPGWLPVSESVTRST--- 23393

Query: 1323  YTVTGLEPGIDYDISVITLINGG-----ESAPTTLTQQTAVP-PPTDLRFTNIGPDTMRV 1376
             +  T L  G +Y   V      G     +S          +P PP  L+  ++  D M +
Sbjct: 23394 FKFTRLTEGNEYVFRVAATNRFGIGSYLQSEVIECRSSIRIPGPPETLQIFDVSRDGMTL 23453

Query: 1377  TWAPPPS---IDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVY 1433
             TW PP       +T ++V    V+ +  V    +  +      T L  G EY   V+++ 
Sbjct: 23454 TWYPPEDDGGSQVTGYIVERKEVRADRWVRVNKVPVTMTRYRSTGLTEGLEYEHRVTAIN 23513

Query: 1434  EQHESTPLR-GRQKTGLD------SPTGIDFSDITANSFTVHWIAPR----ATITGYRIR 1482
              +    P R  +    +D       P     +D T  S ++ W  P     + +TGY I 
Sbjct: 23514 ARGSGKPSRPSKPIVAMDPIAPPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIE 23573

Query: 1483  HHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVP 1542
                       + +  P      TLT+L  G EY   ++A N         G     ++VP
Sbjct: 23574 MQKVDQHEWTKCNTTPTKIREYTLTHLPQGAEYRFRVLACNA--------GGPGEPAEVP 23625

Query: 1543  RDLEVVAAT--PTSLLISWDAPAVTVRY---YRITYGETGGNSPVQEFTVPGSKSTATIS 1597
               ++V      P   L       + VR     R+T    G   P+ ++T  G +  +  +
Sbjct: 23626 GTVKVTEMLEYPDYELDERYQEGIFVRQGGVIRLTIPIKGKPFPICKWTKEG-QDISKRA 23684

Query: 1598  GLKPGVDYTITVYAVTGRGDS---------PASSKPISINYRTEIDKPSQ----MQVTDV 1644
              +     +T  V     RGDS             K + I  R  I  P+     ++  D+
Sbjct: 23685 MIATSETHTELVIKEADRGDSGTYDLVLENKCGKKAVYIKVRV-IGSPNSPEGPLEYDDI 23743

Query: 1645  QDNSISVKWLPSS----SPVTGYRVTT--TPKNGPGPTKTKTAGPDQTEMTIEGLQPTVE 1698
             Q  S+ V W P +    + + GY +     PK       ++  G   T + ++GL+  VE
Sbjct: 23744 QVRSVRVSWRPPADDGGADILGYILERREVPKAAWYTIDSRVRG---TSLVVKGLKENVE 23800

Query: 1699  YVVSVYAQNPSGESQPLVQ----TAVTNIDRPKGLA----FTDVDVDSIKIAWESPQGQ- 1749
             Y   V A+N  G S+PL      T  T ++ P+  +      DV   S+ ++W  P+   
Sbjct: 23801 YHFRVSAENQFGISKPLKSEEPVTPKTPLNPPEPPSNPPEVLDVTKSSVSLSWSRPKDDG 23860

Query: 1750  VSRYRVTYSSPEDGIHELFPAPDGEEDTAEL---QGLRPGSEYTVSVVALHD------DM 1800
              SR    Y   ++   + +   +  + T  +    GL P +EY   ++A +D        
Sbjct: 23861 GSRVTGYYIERKETSTDKWVRHNKTQITTTMYTVTGLVPDAEYQFRIIAQNDVGLSETSP 23920

Query: 1801  ESQPLIGTQSTAIPA-PTDLKFTQVTPTSLSAQWTPPNV----QLTGYRVRVTPKEKTGP 1855
              S+P++       P+ P +L+   ++  S++ QW  P      ++ GY V       +  
Sbjct: 23921 ASEPVVCKDPFDKPSQPGELEILSISKDSVTLQWEKPECDGGKEILGYWVEYRQSGDSAW 23980

Query: 1856  MKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRP---AQGVVTTL-ENVSPPRRA 1911
              K            + GL+ AT+YE  V+A  +T  SRP   A  + T L    +P  R 
Sbjct: 23981 KKSNKERIKDKQFTIGGLLEATEYEFRVFAENETGLSRPRRTAMSIKTKLTSGEAPGIRK 24040

Query: 1912  RVTDAT 1917
              + D T
Sbjct: 24041 EMKDVT 24046



 Score = 99.8 bits (247), Expect = 3e-20
 Identities = 244/1107 (22%), Positives = 422/1107 (38%), Gaps = 171/1107 (15%)

Query: 1092 PPYNTEVTET---TIVITWT-PAPRIGFKLGVRPSQGGEAPREV------TSDSGSIVVS 1141
            P  N EVTET    + + W  P    G K+     +  +  R+        ++S    V+
Sbjct: 6595 PVRNLEVTETFDGEVSLAWEEPLTDGGSKIIGYVVERRDIKRKTWVLATDRAESCEFTVT 6654

Query: 1142 GLTPG-VEYVYTIQVLR-----DGQERDAPIV--NKVVTPLSPPTNLHLEANPDTGVLTV 1193
            GL  G VEY++ +         +  E D P+   +K   P  PP N+ +      GV ++
Sbjct: 6655 GLQKGGVEYLFRVSARNRVGTGEPVETDNPVEARSKYDVP-GPPLNVTITDVNRFGV-SL 6712

Query: 1194 SWERSTTP---DITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYT- 1249
            +WE        +IT Y I        + ++    V A+  S T  ++  G EY+  V   
Sbjct: 6713 TWEPPEYDGGAEITNYVIELRDKTSIRWDTAM-TVRAEDLSATVTDVVEGQEYSFRVRAQ 6771

Query: 1250 --VKDDKES-----VPISDTIIPEVPQLTDLSFVDITDSSIGLRWTPL---NSSTIIGYR 1299
              +   K S     V ++D I    P + +L+  D T SS+ L+W P      S I+GY 
Sbjct: 6772 NRIGVGKPSAATPFVKVADPIERPSPPV-NLTSSDQTQSSVQLKWEPPLKDGGSPILGYI 6830

Query: 1300 ITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLT------ 1353
            I     G+   I  +        Y VTGLE G  Y   V      G S P+ +       
Sbjct: 6831 IERCEEGKDNWIRCNMKLVPELTYKVTGLEKGNKYLYRVSAENKAGVSDPSEILGPLTAD 6890

Query: 1354 ----------------QQTAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVK 1397
                             +  VP P  +   + G      TW     +  T   V+   +K
Sbjct: 6891 DAFVEPTMDLSAFKDGLEVIVPNPITILVPSTGYPRPTATWCFGDKVLETGDRVK---MK 6947

Query: 1398 NEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHE-STPLRGRQKTGLDSPTGID 1456
                 AEL ISPS+ +      L     V ++S   + +  + P          +P  + 
Sbjct: 6948 TLSAYAELVISPSERSDKGIYTLKLENRVKTISGEIDVNVIARP---------SAPKELK 6998

Query: 1457 FSDITANSFTVHWIAP----RATITGYRIRHHPEHFSGRPREDRVPHSRNSI--TLTNLT 1510
            F DIT +S  + W  P     + +TGY +    +    R    +V      +  T+ +L 
Sbjct: 6999 FGDITKDSVHLTWEPPDDDGGSPLTGYVVE---KREVSRKTWTKVMDFVTDLEFTVPDLV 7055

Query: 1511 PGTEYVVSIVALN-------GREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAP- 1562
             G EY+  + A N          + P+ +   +TV D P +++    T  S+ ++WD P 
Sbjct: 7056 QGKEYLFKVCARNKCGPGEPAYVDEPVNMSTPATVPDPPENVKWRDRTANSIFLTWDPPK 7115

Query: 1563 ---AVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSP 1619
                  ++ Y +     G +  V     P +++   ++GL+ G  Y   V A+  +G   
Sbjct: 7116 NDGGSRIKGYIVERCPRGSDKWV-ACGEPVAETKMEVTGLEEGKWYAYRVKALNRQG--- 7171

Query: 1620 ASSKPISINYRTEIDKPS-QMQVTDVQDNS---ISVKWLPSSSPVTGYRV----TTTPKN 1671
             +SKP          +P+ ++Q  D Q+     + VK L   +   G ++    T T K 
Sbjct: 7172 -ASKP---------SRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKP 7221

Query: 1672 GPGPTKTKT--AGPDQTEMTIEGL--QPTVEYVVS---------VYAQNPSGESQPLVQT 1718
             P  T TK          +TIE +  + TV  V S         + A N  G +  +V+ 
Sbjct: 7222 EPKITWTKADMILKQDKRITIENVPKKSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEV 7281

Query: 1719 AVTNIDR---PKGLAFTDVDVDSIKIAWESPQ----GQVSRYRVTYSSPEDGI-HELFPA 1770
             V  +D+   P     TDV  +S  + W  P+     +++ Y V   + +  + H+L  +
Sbjct: 7282 NV--LDKPGPPAAFDITDVTNESCLLTWNPPRDDGGSKITNYVVERRATDSEVWHKL--S 7337

Query: 1771 PDGEEDTAELQGLRPGSEYTVSVVA-----LHDDMESQPLIGTQSTAIPA-PTDLKFTQV 1824
               ++   +   L P  EY   V A     + + +++ P+        P  PT L+ + +
Sbjct: 7338 STVKDTNFKATKLIPNKEYIFRVAAENMYGVGEPVQASPITAKYQFDPPGPPTRLEPSDI 7397

Query: 1825 TPTSLSAQWTPPN----VQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYE 1880
            T  +++  W  P+      +TGY V     +    ++   +    ++  V GL    KY 
Sbjct: 7398 TKDAVTLTWCEPDDDGGSPITGYWVERLDPDTDKWVRCNKMPVKDTTYRVKGLTNKKKYR 7457

Query: 1881 VSVYALKDTLTSRPAQG-----VVTTLENVSPPRRARVTDATETTITISWRTKTE----- 1930
              V A       +P++      +   ++   PP +  V D  +T++ ++W TK E     
Sbjct: 7458 FRVLAENLAGPGKPSKSTEPILIKDPIDPPWPPGKPTVKDVGKTSVRLNW-TKPEHDGGA 7516

Query: 1931 TITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPV---- 1986
             I  + ++ +       ++         + + GL  G +Y   +  +N    S P     
Sbjct: 7517 KIESYVIEMLKTGTDEWVRVAEGVPTTQHLLPGLMEGQEYSFRVRAVNKAGESEPSEPSD 7576

Query: 1987 VIDASTAIDAPSNLRFLAT---TPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREVV 2039
             +     +  PS  R+L     T N+  + W  P     + IT YI++         + V
Sbjct: 7577 PVLCREKLYPPSPPRWLEVINITKNTADLKWTVPEKDGGSPITNYIVEKRDVRRKGWQTV 7636

Query: 2040 PRPRPGVTEATITGLEPGTEYTIYVIA 2066
                   T+ T+T L  G+ Y   V A
Sbjct: 7637 DTTVKD-TKCTVTPLTEGSLYVFRVAA 7662



 Score = 96.3 bits (238), Expect = 3e-19
 Identities = 294/1454 (20%), Positives = 518/1454 (35%), Gaps = 209/1454 (14%)

Query: 684   IQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSA 743
             I+  G Q + +      + S P+T   +     P  PL      VT +TA    ++W   
Sbjct: 18275 IRTDGGQYILKLSNVGGTKSIPITVKVLDRPGPPEGPL-----KVTGVTAEKCYLAWNPP 18329

Query: 744   SDTVSGFRVEYELSEEGDEPQYLDLPSTATSVN-----IPDLLPGRKYI-----VNVYQI 793
                  G  + + + E+  E   L     +T V      +  LLPG +YI     VN Y I
Sbjct: 18330 LQD-GGANISHYIIEKR-ETSRLSWTQVSTEVQALNYKVTKLLPGNEYIFRVMAVNKYGI 18387

Query: 794   SEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRP----QAPITGYRIVYSPSV 849
              E  E   + + +    P  P  P V  +   S+VV W+RP       I GY I+     
Sbjct: 18388 GEPLESGPVTACNPYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGY-ILEKRDK 18446

Query: 850   EGSSTELNLPETANSVTL--SDLQPGVQYNITIYAVEE---NQESTPVVIQQETTGTPRS 904
             EG        +T   + L  + L  G  Y   + A       + S P V  +        
Sbjct: 18447 EGVRWTKCNKKTLTDLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYR------AC 18500

Query: 905   DTVPSPRDLQFVEVTDV---KVTIMWTPP----ESAVTGYRVDV------------IPVN 945
             D +  P      +VTD     V++ W+ P     + V GY V+V             P  
Sbjct: 18501 DALYPPGPPSNPKVTDTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAADEWTTCTPPTG 18560

Query: 946   LPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLT------AQQ-----T 994
             L G+              VT L     Y F++ A++     +P T      AQ+      
Sbjct: 18561 LQGKQ-----------FTVTKLKENTEYNFRICAINSEGVGEPATLPGSVVAQERIEPPE 18609

Query: 995   TKLDAPTNLQFVNETDSTVLVRWT---PPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKY 1051
              +LDA      V    +T+ +  T    P  ++   +    LT R    Q  V  S +  
Sbjct: 18610 IELDADLRKVVVLRASATLRLFVTIKGRPEPEVKWEKAEGILTDRA---QIEVTSSFTML 18666

Query: 1052  PLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAP 1111
              + N+        +L     +        V     P + +     EV + ++ ++W P  
Sbjct: 18667 VIDNVTRFDSGRYNLTLENNSGSKTAFVNVRVLDSPSAPVNLTIREVKKDSVTLSWEPPL 18726

Query: 1112  RIGFKLGVRPSQGGEAPREVTSDSGSIV----------VSGLTPGVEYVYTIQVLRD--- 1158
               G   G + +      RE T  + + +          +  L  G  Y + +    +   
Sbjct: 18727 IDG---GAKITNYIVEKRETTRKAYATITNNCTKTTFRIENLQEGCSYYFRVLASNEYGI 18783

Query: 1159  GQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTT---PDITGYRITTTPTNG 1215
             G   +     KV  P  PP  + L  +      T+ WE+  +     ITGY +       
Sbjct: 18784 GLPAETTEPVKVSEPPLPPGRVTL-VDVTRNTATIKWEKPESDGGSKITGYVVEMQTKGS 18842

Query: 1216  QQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPEVPQLTDLSF 1275
             ++ ++  +V   +    T   L+ G EY   V  V +   S P     +P + +  ++  
Sbjct: 18843 EKWSTCTQVKTLE---ATISGLTAGEEYVFRVAAVNEKGRSDP-RQLGVPVIARDIEIK- 18897

Query: 1276  VDITDSSIGLRWTPLNSSTIIGYRITVVAAG----------EGIPIFEDFVDSSVGYYTV 1325
                   S+ L +   N       +I V   G          +G  + E    +     TV
Sbjct: 18898 -----PSVELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKTV 18952

Query: 1326  TGL--EPGIDYDISVITLI----NGGESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTWA 1379
             T L  +     D+    L      G  + P T+       PP  +R   +  D++ ++W 
Sbjct: 18953 TSLSIKEASKEDVGTYELCVSNSAGSITVPITIIVLDRPGPPGPIRIDEVSCDSITISWN 19012

Query: 1380  PPP---SIDLTNFLVRYSPVKNEEDVAE---LSISPSDNAVVLTNLLPGTEYVVSVSS-- 1431
             PP       ++N++V     K E        +S + +  ++ +  L  G+EY   V +  
Sbjct: 19013 PPEYDGGCQISNYIVE----KKETTSTTWHIVSQAVARTSIKIVRLTTGSEYQFRVCAEN 19068

Query: 1432  ---VYEQHESTPLRGRQKTGLDSPTGI-DFSDITANSFTVHWIAP----RATITGYRIRH 1483
                     ES+ +          P G       T ++  V W  P     + + GY + +
Sbjct: 19069 RYGKSSYSESSAVVAEYPFSPPGPPGTPKVVHATKSTMLVTWQVPVNDGGSRVIGYHLEY 19128

Query: 1484  HPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN----GREESPLLIGQQSTVS 1539
                      + +++  +   + ++ L  G  Y   + A N    G+              
Sbjct: 19129 KERSSILWSKANKILIADTQMKVSGLDEGLMYEYRVYAENIAGIGKCSKSCEPVPARDPC 19188

Query: 1540  DVPRDLEVVAATPTSLLISWDAP----AVTVRYYRITYGETGGNSPVQEFTVPGSKSTAT 1595
             D P   EV   T  S+ + W  P       +  Y +   E      ++       ++   
Sbjct: 19189 DPPGQPEVTNITRKSVSLKWSKPHYDGGAKITGYIVERRELPDGRWLKCNYTNIQETYFE 19248

Query: 1596  ISGLKPGVDYTITVYAVTGRGD-SPASSKPISINYRTEIDKPSQMQVTDVQDNSI--SVK 1652
             ++ L     Y   V+A       S  S     I  + +++ P  M     +D  +  + +
Sbjct: 19249 VTELTEDQRYEFRVFARNAADSVSEPSESTGPIIVKDDVEPPRVMMDVKFRDVIVVKAGE 19308

Query: 1653  WLPSSSPVTG--YRVTTTPKNG---PGPTKTKTAGPD-QTEMTIEGL--QPTVEYVVSVY 1704
              L  ++ + G    V +  K+G       +T+    D  T +T++    + T +YV+++ 
Sbjct: 19309 VLKINADIAGRPLPVISWAKDGIEIEERARTEIISTDNHTLLTVKDCIRRDTGQYVLTL- 19367

Query: 1705  AQNPSGESQPLVQTAVTNIDRPKG--LAFTDVDVDSIKIAWESPQ----GQVSRYRVTYS 1758
              +N +G     V   V +   P    L    +  +   ++W  PQ      +  Y V   
Sbjct: 19368 -KNVAGTRSVAVNCKVLDKPGPPAGPLEINGLTAEKCSLSWGRPQEDGGADIDYYIV--- 19423

Query: 1759  SPEDGIHELFPAPDGE--EDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPA- 1815
                +  H  +   +GE    + ++  L  G+EY   V  ++     +PL   +S AI A 
Sbjct: 19424 EKRETSHLAWTICEGELQMTSCKVTKLLKGNEYIFRVTGVNKYGVGEPL---ESVAIKAL 19480

Query: 1816  --------PTDLKFTQVTPTSLSAQWTPP----NVQLTGYRVRVTPKEKTGPMKEINLAP 1863
                     PT L+ T VT  S++  W+ P      +++GY +    K     ++      
Sbjct: 19481 DPFTVPSPPTSLEITSVTKESMTLCWSRPESDGGSEISGYIIERREKNSLRWVRVNKKPV 19540

Query: 1864  DSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQ--GVVTTLENV---SPPRRARVTDATE 1918
                 V  +GL    +YE  VYA      S P++   ++   + V   SPP + ++ D+ +
Sbjct: 19541 YDLRVKSTGLREGCEYEYRVYAENAAGLSLPSETSPLIRAEDPVFLPSPPSKPKIVDSGK 19600

Query: 1919  TTITISWRTKT----ETITGFQVD---AVPANGQTPIQRTIKPDVRSYTITGLQPGTDYK 1971
             TTITI+W          ITG+ V+   +   + +T IQ     +   YTI+GL  G +Y 
Sbjct: 19601 TTITIAWVKPLFDGGAPITGYTVEYKKSDDTDWKTSIQSLRGTE---YTISGLTTGAEYV 19657

Query: 1972  IYLYTLNDNARSSP 1985
               + ++N    S P
Sbjct: 19658 FRVKSVNKVGASDP 19671



 Score = 95.5 bits (236), Expect = 6e-19
 Identities = 319/1473 (21%), Positives = 540/1473 (36%), Gaps = 232/1473 (15%)

Query: 777   IPDLLPGRKYIVNVYQISEDG--EQSLILSTSQTTAPDAPPD------PTVDQVDDTSIV 828
             + DL+ G +Y   V  ++  G  + S  +       PD PP         V++  + +IV
Sbjct: 9581  VEDLVEGGEYEFRVKAVNAAGVSKPSATVGPCDCQRPDMPPSIDLKEFMEVEEGTNVNIV 9640

Query: 829   VR----------WSR--PQAPITGYRIVYSPSVE----GSSTELNLPETANSVTLSDLQP 872
              +          W +  P+ P     ++Y   V       +  L +P++  S T      
Sbjct: 9641  AKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDT------ 9694

Query: 873   GVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE- 931
             G+    TI AV  N  +    ++    G P     P    ++F  V+  ++T+ W PP+ 
Sbjct: 9695  GLY---TITAVN-NLGTASKEMRLNVLGRPGPPVGP----IKFESVSADQMTLSWFPPKD 9746

Query: 932   ---SAVTGYRVDVIPVNLPG-EHGQRLPISRNTFAEVTGLSPGVTYYFKVFA-----VSH 982
                S +T Y ++    N     H    P  +     +  L  G  Y F++ A     +  
Sbjct: 9747  DGGSKITNYVIEKREANRKTWVHVSSEP--KECTYTIPKLLEGHEYVFRIMAQNKYGIGE 9804

Query: 983   GRESKPLTAQQTTKLD-APTNLQFVNETDSTVLVRWTPPR----AQITGYRLTVGLTRRG 1037
               +S+P TA+    +  AP      + T +++ V W  P     + +TGY L +  T   
Sbjct: 9805  PLDSEPETARNLFSVPGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPVTGYWLEMKDTTSK 9864

Query: 1038  QPRQYNVGPSVS-----KYPLRNLQPASEYTVSLVAIKGNQESPK------ATGVFTTLQ 1086
             + ++ N  P  +      Y +  L   S+Y   + AI      P       AT       
Sbjct: 9865  RWKRVNRDPIKAMTLGVSYKVTGLIEGSDYQFRVYAINAAGVGPASLPSDPATARDPIAP 9924

Query: 1087  PGSSIPPYNTEVTETTIVITWTPAPRIGFKLG----VRPSQGGEAPREVTSDSG----SI 1138
             PG   P   T+ T+++  + W+P  + G        V   + G+   E   D       +
Sbjct: 9925  PGPPFPKV-TDWTKSSADLEWSPPLKDGGSKVTGYIVEYKEEGKEEWEKGKDKEVRGTKL 9983

Query: 1139  VVSGLTPGVEYVYTIQVLRD---GQERDAPIVNKVVTPLSPPTNLHLEANP-DTGVLTVS 1194
             VV+GL  G  Y + ++ +     G+  +   V ++   L  P +L L+A+  D  V+   
Sbjct: 9984  VVTGLKEGAFYKFRVRAVNIAGIGEPGEVTDVIEMKDRLVSP-DLQLDASVRDRIVVHAG 10042

Query: 1195  WERSTTPDITGYRITTTPTNGQQGNSLEEVV---HADQSSCTFDNLSPGLEYNVSVYTVK 1251
                     ++G    T   N  +    +E      A  SS    N     +    VY++ 
Sbjct: 10043 GVIRIIAYVSGKPPPTVTWNMNERTLPQEATIETTAISSSMVIKNCQRSHQ---GVYSLL 10099

Query: 1252  DDKESVPISDTIIPEV-----PQLTDLSFVDITDSSIGLRW-TPLNS--STIIGYRITVV 1303
                E+     TII +V     P  T     ++T+ S  L W +P +   S I  Y I   
Sbjct: 10100 AKNEAGERKKTIIVDVLDVPGPVGTPFLAHNLTNESCKLTWFSPEDDGGSPITNYVIEKR 10159

Query: 1304  AAGEGI--PIFEDFVDSSVGYYTVTGLEPGIDY--DISVITLINGGESAPTT----LTQQ 1355
              +      P+       +    TV GL  G  Y   I+    I  G    T+    + + 
Sbjct: 10160 ESDRRAWTPVTYTVTRQNA---TVQGLIQGKAYFFRIAAENSIGMGPFVETSEALVIREP 10216

Query: 1356  TAVPP-PTDLRFTNIGPDTMRVTWAPPP---SIDLTNFLVRYSPVKNEEDVAELSISPSD 1411
               VP  P DL    +  +T+ +TW PP      ++ N+++    +  E+     + +   
Sbjct: 10217 ITVPERPEDLEVKEVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEKFHKVTNDNLLS 10276

Query: 1412  NAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQ----KTGLDSPT-GIDFSDITANSFT 1466
                 +  L  G  Y   VS+V    +  P    +    K  L  PT  +DF D      T
Sbjct: 10277 RKYTVKGLKEGDTYEYRVSAVNIVGQGKPSFCTKPITCKDELAPPTLHLDFRD----KLT 10332

Query: 1467  VHWIAPRATITGYRIRHHPEHFSGRPR------EDRVPHSRNSITLTNLTPGTEYVVSIV 1520
             +  +     +TG         +SG+P+      +D      +  T    TP T  +  I 
Sbjct: 10333 IR-VGEAFALTG--------RYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATLALEKIK 10383

Query: 1521  ALNGREESPLLIGQQST--------VSDVPRDLEVVA------ATPTSLLISWDAP---- 1562
             A         ++ + ST        V+ V R    V        T   ++ISW  P    
Sbjct: 10384 AKRSDSGKYCVVVENSTGSRKGFCQVNVVDRPGPPVGPVSFDEVTKDYMVISWKPPLDDG 10443

Query: 1563  AVTVRYYRITYGETGGN--SPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDS-P 1619
                +  Y I   E G +   PV   T   +K+T  +S L  G DY   ++A    G S P
Sbjct: 10444 GSKITNYIIEKKEVGKDVWMPV---TSASAKTTCKVSKLLEGKDYIFRIHAENLYGISDP 10500

Query: 1620  ASSKPISINYRTEI-DKPSQMQVTDVQDNSISVKWLP---SSSPVTGY---RVTTTPKNG 1672
               S  +    R  + D P Q  VT+V  +S  V W        P+T Y   +  T  K  
Sbjct: 10501 LVSDSMKAKDRFRVPDAPDQPIVTEVTKDSALVTWNKPHDGGKPITNYILEKRETMSKRW 10560

Query: 1673  PGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQN------PSGESQPL-VQTAVTNIDR 1725
                TK        T+  +  L    +Y   V A+N      PS  S+P+  +  +     
Sbjct: 10561 ARVTKDPIH--PYTKFRVPDLLEGCQYEFRVSAENEIGIGDPSPPSKPVFAKDPIAKPSP 10618

Query: 1726  PKGLAFTDVDVDSIKIAWESPQ----GQVSRYRVTYSSPEDGI-HELFPAPDGEEDTA-E 1779
             P      D   +S+ + W+ P+     ++  Y V Y    D         P+   +T  +
Sbjct: 10619 PVNPEAIDTTCNSVDLTWQPPRHDGGSKILGYIVEYQKVGDEEWRRANHTPESCPETKYK 10678

Query: 1780  LQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTS-LSAQWTPPNV 1838
             + GLR G  Y   V+A++   ES P        +P P  +K     P   L A       
Sbjct: 10679 VTGLRDGQTYKFRVLAVNAAGESDP------AHVPEPVLVKDRLEPPELILDANMAREQH 10732

Query: 1839  QLTGYRVRVT------PKEKTGPMKEINLAPDSSSVVVSGLMVATKYEV--------SVY 1884
                G  +R++      P  K    KE   AP  + + V+   V +K E+         +Y
Sbjct: 10733 IKVGDTLRLSAIIKGVPFPKVTWKKEDRDAPTKARIDVTP--VGSKLEIRNAAHEDGGIY 10790

Query: 1885  AL--KDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTE----TITGFQVD 1938
             +L  ++   S+     V  L+   PPR   V++  + +  ++W+   +     IT + V+
Sbjct: 10791 SLTVENPAGSKTVSVKVLVLDKPGPPRDLEVSEIRKDSCYLTWKEPLDDGGSVITNYVVE 10850

Query: 1939  A--VPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPV-------VID 1989
                V +   +P+  T K   +S+    L  G  Y   +   N   R   V        +D
Sbjct: 10851 RRDVASAQWSPLSATSKK--KSHFAKHLNEGNQYLFRVAAENQYGRGPFVETPKPIKALD 10908

Query: 1990  ASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREVVPRPRPG 2045
                    P +L  +      + + W  P     + ITGY+++Y++ G+  ++ +      
Sbjct: 10909 PLHPPGPPKDLHHVDVDKTEVSLVWNKPDRDGGSPITGYLVEYQEEGT--QDWIKFKTVT 10966

Query: 2046  VTEATITGLEPGTEYTIYVIALKNNQKSEPLIG 2078
               E  +TGL+ G  Y   V       K+E ++G
Sbjct: 10967 NLECVVTGLQQGKTYRFRV-------KAENIVG 10992



 Score = 95.1 bits (235), Expect = 7e-19
 Identities = 312/1572 (19%), Positives = 569/1572 (36%), Gaps = 228/1572 (14%)

Query: 616   ITETPSQPNSHPIQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLK 672
             +T T     S  + W  P+    S +  Y++  +PK +  +W         N+  + GL 
Sbjct: 17722 VTLTDVSQTSASLMWEKPEHDGGSRVLGYVVEMQPKGTE-KWSIVAESKVCNA-VVTGLS 17779

Query: 673   PGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETT---PFSP--LVATSES 727
              G  Y+ ++ +  + G  +             PV +  +T + +   PF+   + A  + 
Sbjct: 17780 SGQEYQFRVKAYNEKGKSD-------PRVLGVPVIAKDLTIQPSLKLPFNTYSIQAGEDL 17832

Query: 728   VTEITASSFV---VSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGR 784
               EI         +SWV   + +              +   +++  TATS  +  +  G 
Sbjct: 17833 KIEIPVIGRPRPNISWVKDGEPLK-------------QTTRVNVEETATST-VLHIKEGN 17878

Query: 785   KYIVNVYQISED---GEQSLILSTSQTTAPDAPPDPT-VDQVDDTSIVVRWSRPQ----A 836
             K     Y ++     G  +  LS      P  P  P   D+V    +V+ W  P      
Sbjct: 17879 KDDFGKYTVTATNSAGTATENLSVIVLEKPGPPVGPVRFDEVSADFVVISWEPPAYTGGC 17938

Query: 837   PITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQ 896
              I+ Y +    +   +   ++      ++ ++ L+ G +Y   I+A     +S P+  + 
Sbjct: 17939 QISNYIVEKRDTTTTTWHMVSATVARTTIKITKLKTGTEYQFRIFAENRYGKSAPLDSKA 17998

Query: 897   ETTGTPRSDTVPSPRDLQFV-EVTDVKVTIMWTPPES----AVTGYRVDVIPVN-LPGEH 950
                  P  +  P P    FV  ++  ++ + W  P +     + GY ++    N +    
Sbjct: 17999 VIVQYPFKE--PGPPGTPFVTSISKDQMLVQWHEPVNDGGTKIIGYHLEQKEKNSILWVK 18056

Query: 951   GQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQT----TKLDAPTNLQFV 1006
               + PI    F + TGL  G+ Y FKV A +     KP    +        D P   + +
Sbjct: 18057 LNKTPIQDTKF-KTTGLDEGLEYEFKVSAENIVGIGKPSKVSECFVARDPCDPPGRPEAI 18115

Query: 1007  NETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSV-SKYPLRNLQPASE 1061
               T + V ++W  P     ++ITGY +       G+  + +    + +++ +  L     
Sbjct: 18116 VITRNNVTLKWKKPAYDGGSKITGYIVEKKDLPDGRWMKASFTNVLETEFTVSGLVEDQR 18175

Query: 1062  YTVSLVA--IKGNQESPK-ATGVFTTLQ----PGSSIPPYNTEVT-----ETTIV---IT 1106
             Y   ++A    GN   P  ++G  T       P +S+ P   +V      ET ++   I 
Sbjct: 18176 YEFRVIARNAAGNFSEPSDSSGAITARDEIDAPNASLDPKYKDVIVVHAGETFVLEADIR 18235

Query: 1107  WTPAPRIGFKLGVRPSQGGEAPREVTS--DSGSIVVSGL--TPGVEYVYTIQVLRDGQER 1162
               P P + +    +  +   A  E+ S     ++VV     T G +Y+  +++   G  +
Sbjct: 18236 GKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQYI--LKLSNVGGTK 18293

Query: 1163  DAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWE---RSTTPDITGYRITTTPTNGQQGN 1219
               PI  KV+    PP               ++W    +    +I+ Y I    T+     
Sbjct: 18294 SIPITVKVLDRPGPPEGPLKVTGVTAEKCYLAWNPPLQDGGANISHYIIEKRETSRLSWT 18353

Query: 1220  SLEEVVHADQSSCTFDNLSPGLEY-----NVSVYTVKDDKESVPIS---------DTIIP 1265
              +   V A     T   L PG EY      V+ Y + +  ES P++             P
Sbjct: 18354 QVSTEVQALNYKVT--KLLPGNEYIFRVMAVNKYGIGEPLESGPVTACNPYKPPGPPSTP 18411

Query: 1266  EVPQLTDLSFV-----DITDSSI-------------GLRWTPLNSSTIIGYRITVVAAGE 1307
             EV  +T  S V      + D                G+RWT  N  T+   R+ V    E
Sbjct: 18412 EVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDKEGVRWTKCNKKTLTDLRLRVTGLTE 18471

Query: 1308  GIPI-FEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAVPPPTDLRF 1366
             G    F    +++ G    +  EP + Y         G               PP++ + 
Sbjct: 18472 GHSYEFRVAAENAAGVGEPS--EPSVFYRACDALYPPG---------------PPSNPKV 18514

Query: 1367  TNIGPDTMRVTWAPP---PSIDLTNFLVRYSPVKNEE-DVAELSISPSDNAVVLTNLLPG 1422
             T+    ++ + W+ P       +  ++V       +E                +T L   
Sbjct: 18515 TDTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAADEWTTCTPPTGLQGKQFTVTKLKEN 18574

Query: 1423  TEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGY-RI 1481
             TEY   + ++  +    P                  ++ A+   V  +   AT+  +  I
Sbjct: 18575 TEYNFRICAINSEGVGEPATLPGSVVAQERIEPPEIELDADLRKVVVLRASATLRLFVTI 18634

Query: 1482  RHHPEHFSGRPREDRVPHSRNSITLT---------NLTPGTEYVVSIVALNGREESPLLI 1532
             +  PE      + + +   R  I +T         N+T       ++   N        +
Sbjct: 18635 KGRPEPEVKWEKAEGILTDRAQIEVTSSFTMLVIDNVTRFDSGRYNLTLENNSGSKTAFV 18694

Query: 1533  GQQSTVS-DVPRDLEVVAATPTSLLISWDAPAVT----VRYYRITYGETGGNSPVQEFTV 1587
               +   S   P +L +      S+ +SW+ P +     +  Y +   ET   +     T 
Sbjct: 18695 NVRVLDSPSAPVNLTIREVKKDSVTLSWEPPLIDGGAKITNYIVEKRETTRKA-YATITN 18753

Query: 1588  PGSKSTATISGLKPGVDYTITVYAVT--GRGDSPASSKPISINYRTEIDKPSQMQVTDVQ 1645
               +K+T  I  L+ G  Y   V A    G G    +++P+ ++       P ++ + DV 
Sbjct: 18754 NCTKTTFRIENLQEGCSYYFRVLASNEYGIGLPAETTEPVKVSEPPL--PPGRVTLVDVT 18811

Query: 1646  DNSISVKW-LPSS---SPVTGYRVTTTPKNGPGPTKTKTAGPDQT-EMTIEGLQPTVEYV 1700
              N+ ++KW  P S   S +TGY V    K   G  K  T    +T E TI GL    EYV
Sbjct: 18812 RNTATIKWEKPESDGGSKITGYVVEMQTK---GSEKWSTCTQVKTLEATISGLTAGEEYV 18868

Query: 1701  VSVYAQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVD-SIKIAWESPQGQVSRYRVTYSS 1759
               V A N  G S P  Q  V  I R       D+++  S+++ + +   + +R ++    
Sbjct: 18869 FRVAAVNEKGRSDPR-QLGVPVIAR-------DIEIKPSVELPFHTFNVK-AREQLKIDV 18919

Query: 1760  PEDGIHELFP--APDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQ-------- 1809
             P  G  +       DG+    E   +   S  TV+ +++ +   S+  +GT         
Sbjct: 18920 PFKGRPQATVNWRKDGQT-LKETTRVNVSSSKTVTSLSIKE--ASKEDVGTYELCVSNSA 18976

Query: 1810  -STAIPA----------PTDLKFTQVTPTSLSAQWTPPNV----QLTGYRVRVTPKEKTG 1854
              S  +P           P  ++  +V+  S++  W PP      Q++ Y V    KE T 
Sbjct: 18977 GSITVPITIIVLDRPGPPGPIRIDEVSCDSITISWNPPEYDGGCQISNYIVE--KKETTS 19034

Query: 1855  PMKEI-NLAPDSSSVVVSGLMVATKYEVSVYAL----KDTLTSRPAQGVVTTLENVSPPR 1909
                 I + A   +S+ +  L   ++Y+  V A     K + +   A           PP 
Sbjct: 19035 TTWHIVSQAVARTSIKIVRLTTGSEYQFRVCAENRYGKSSYSESSAVVAEYPFSPPGPPG 19094

Query: 1910  RARVTDATETTITISWRTKT----ETITGFQVDAVPANG--QTPIQRTIKPDVRSYTITG 1963
               +V  AT++T+ ++W+         + G+ ++    +    +   + +  D +   ++G
Sbjct: 19095 TPKVVHATKSTMLVTWQVPVNDGGSRVIGYHLEYKERSSILWSKANKILIADTQ-MKVSG 19153

Query: 1964  LQPGTDYKIYLYTLN----DNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPR- 2018
             L  G  Y+  +Y  N         S   + A    D P        T  S+ + W  P  
Sbjct: 19154 LDEGLMYEYRVYAENIAGIGKCSKSCEPVPARDPCDPPGQPEVTNITRKSVSLKWSKPHY 19213

Query: 2019  ---ARITGYIIK 2027
                A+ITGYI++
Sbjct: 19214 DGGAKITGYIVE 19225



 Score = 94.7 bits (234), Expect = 1e-18
 Identities = 315/1607 (19%), Positives = 572/1607 (35%), Gaps = 282/1607 (17%)

Query: 628  IQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISI 684
            + W  P+    + I  Y++    K     W           + + GL  G  Y  ++ ++
Sbjct: 7505 LNWTKPEHDGGAKIESYVIEML-KTGTDEWVRVAEGVPTTQHLLPGLMEGQEYSFRVRAV 7563

Query: 685  QQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSAS 744
             + G  E +              S+ V      + P       V  IT ++  + W +  
Sbjct: 7564 NKAGESEPSE------------PSDPVLCREKLYPPSPPRWLEVINITKNTADLKW-TVP 7610

Query: 745  DTVSGFRVEYELSEEGDEP----QYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGE-- 798
            +   G  +   + E+ D      Q +D     T   +  L  G  Y+  V   +  G+  
Sbjct: 7611 EKDGGSPITNYIVEKRDVRRKGWQTVDTTVKDTKCTVTPLTEGSLYVFRVAAENAIGQSD 7670

Query: 799  ----QSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ----APITGYRIVYSPSVE 850
                +  +L+    T P  P    V  V    + ++W  P+     PI  Y I     + 
Sbjct: 7671 YTEIEDSVLAKDTFTTPGPPYALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKERL- 7729

Query: 851  GSSTELNLPETAN---SVTLSDLQPGVQYNITIYAVEEN-----QESTPVVIQQETTGTP 902
              +  +   +TA    +  ++D+  G +    + A  E       E T ++  ++ T  P
Sbjct: 7730 -GTRWVKAGKTAGPDCNFRVTDVIEGTEVQFQVRAENEAGVGHPSEPTEILSIEDPTSPP 7788

Query: 903  RSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPVNLPGEHGQRL---P 955
                   P DL   +     + I W PPE    S + GY V++ PV    E   R+   P
Sbjct: 7789 SP-----PLDLHVTDAGRKHIAIAWKPPEKNGGSPIIGYHVEMCPVGT--EKWMRVNSRP 7841

Query: 956  ISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLV 1015
            I    F    G+ P   Y  +V AV+    S+P    +      P     ++     ++V
Sbjct: 7842 IKDLKFKVEEGVVPDKEYVLRVRAVNAIGVSEPSEISENVVAKDPDCKPTIDLETHDIIV 7901

Query: 1016 RWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPL-RNLQPASEYTVSLVAIKGNQE 1074
                    I G +L++ +  R  P      P+VS +   + ++ +   T+    I  + E
Sbjct: 7902 --------IEGEKLSIPVPFRAVPV-----PTVSWHKDGKEVKASDRLTMKNDHISAHLE 7948

Query: 1075 SPKAT----GVFT-TLQP--GSSIPPYN---------------TEVTETTIVITWTP--- 1109
             PK+     G++T TL+   GS+    N               +++T+++  +TW P   
Sbjct: 7949 VPKSVRADAGIYTITLENKLGSATASINVKVIGLPGPCKDIKASDITKSSCKLTWEPPEF 8008

Query: 1110 ---APRIGFKLGVRPSQGGEAPREVTSDSGSI--VVSGLTPGVEYVYTIQVLRD-GQERD 1163
                P + + L  R + G      V S    +   V  L P  EY + ++ +   G    
Sbjct: 8009 DGGTPILHYVLERREA-GRRTYIPVMSGENKLSWTVKDLIPNGEYFFRVKAVNKVGGGEY 8067

Query: 1164 APIVNKVVT-----PLSPPTNLHLEANPDTGVLTVSWERSTTPD---ITGYRITTTPTNG 1215
              + N V+      P  PP ++ +  NP    +T++W+         I GY I       
Sbjct: 8068 IELKNPVIAQDPKQPPDPPVDVEVH-NPTAEAMTITWKPPLYDGGSKIMGYIIEKIAKGE 8126

Query: 1216 QQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYT-----VKDDKESVPISDTIIP-EVPQ 1269
            ++     E +     + T   L  G EY   V       + +   + P +  + P + P+
Sbjct: 8127 ERWKRCNEHL-VPILTYTAKGLEEGKEYQFRVRAENAAGISEPSRATPPTKAVDPIDAPK 8185

Query: 1270 LTDLSFVDIT-------DSSIG------LRWTPLNSSTIIGYRITVVAA-------GEGI 1309
            +   + +++        D+SI       + W   + + I+   I   AA       GE +
Sbjct: 8186 VILRTSLEVKRGDEIALDASISGSPYPTITWIK-DENVIVPEEIKKRAAPLVRRRKGE-V 8243

Query: 1310 PIFEDFVDSSVGYYTVTGLEPGI-----------DYDISVITLIN--GGESAPTTLTQQT 1356
               E FV       ++   + G            D+ + +I + N  G   AP T++   
Sbjct: 8244 QEEEPFVLPLTQRLSIDNSKKGESQLRVRDSLRPDHGLYMIKVENDHGIAKAPCTVSVLD 8303

Query: 1357 AVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVL 1416
               PP +  F +I   ++   W PP   D  + ++ Y+  K ++        P    +V+
Sbjct: 8304 TPGPPINFVFEDIRKTSVLCKWEPPLD-DGGSEIINYTLEKKDK------TKPDSEWIVV 8356

Query: 1417 TNLLPGTEYVVSVSSVYEQHE------------------STPLRGRQKTG-LDSPTGIDF 1457
            T+ L   +Y  SV+ + E  E                  S PL  +   G  D+P     
Sbjct: 8357 TSTLRHCKY--SVTKLIEGKEYLFRVRAENRFGPGPPCVSKPLVAKDPFGPPDAPDKPIV 8414

Query: 1458 SDITANSFTVHWIAPR---ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTE 1514
             D+T+NS  V W  P+   + I GY +     + +   R ++   +     +  L  G  
Sbjct: 8415 EDVTSNSMLVKWNEPKDNGSPILGYWLEKREVNSTHWSRVNKSLLNALKANVDGLLEGLT 8474

Query: 1515 YVVSIVALN----GREESPLLIGQQSTVSD--------VPRDLEVVAATPTSLLISWDAP 1562
            YV  + A N    G+   P       T  D        +PR   V   + T++ + W+ P
Sbjct: 8475 YVFRVCAENAAGPGKFSPP---SDPKTAHDPISPPGPPIPR---VTDTSSTTIELEWEPP 8528

Query: 1563 AVT----VRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDS 1618
            A      +  Y +     G N   +           T+  ++ G DY + V AV   G+ 
Sbjct: 8529 AFNGGGEIVGYFVDKQLVGTNEWSRCTEKMIKVRQYTVKEIREGADYKLRVSAVNAAGEG 8588

Query: 1619 -PASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTK 1677
             P  ++P+++    E  +P  +++       +SVK           R+       P PTK
Sbjct: 8589 PPGETQPVTV---AEPQEPPAVEL------DVSVKGGIQIMAGKTLRIPAVVTGRPVPTK 8639

Query: 1678 --TKTAGP-DQTEMTIEGLQPTVEYVVS-----------VYAQNPSGESQPLVQTAVTNI 1723
              TK  G  D+  + I+ +    E ++            + A N  G      +  V ++
Sbjct: 8640 VWTKEEGELDKDRVVIDNVGTKSELIIKDALRKDHGRYVITATNSCGSKFAAARVEVFDV 8699

Query: 1724 DRP-KGLAFTDVDVDSIKIAWESPQ----GQVSRYRVTYSSPEDGIHELFPAPDGEEDTA 1778
              P   L     +     + W  P+     +++ + +     +  +H      + E    
Sbjct: 8700 PGPVLDLKPVVTNRKMCLLNWSDPEDDGGSEITGFIIERKDAK--MHTWRQPIETERSKC 8757

Query: 1779 ELQGLRPGSEYTVSVVALH-----DDMESQPLIGTQSTAIP-APTDLKFTQVTPTSLSAQ 1832
            ++ GL  G EY   V+A +       +E  P++       P +P  L +T+ T ++++  
Sbjct: 8758 DITGLLEGQEYKFRVIAKNKFGCGPPVEIGPILAVDPLGPPTSPERLTYTERTKSTITLD 8817

Query: 1833 WTPPNVQ----LTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKD 1888
            W  P       + GY +     +K    +       ++S +V  L     YE  V A+ +
Sbjct: 8818 WKEPRSNGGSPIQGYIIEKRRHDKPDFERVNKRLCPTTSFLVENLDEHQMYEFRVKAVNE 8877

Query: 1889 TLTSRPA--QGVVTTLENVSPPRRARVTDATETTIT-------------------ISWRT 1927
               S P+    VV   + V P  + R++   +T                      I W +
Sbjct: 8878 IGESEPSLPLNVVIQDDEVPPTIKLRLSVRGDTIKVKAGEPVHIPADVTGLPMPKIEW-S 8936

Query: 1928 KTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVV 1987
            K ET+     DA+    +   +   K ++          GT      YT+  + R   V 
Sbjct: 8937 KNETVIEKPTDALQITKEEVSRSEAKTELSIPKAVREDKGT------YTVTASNRLGSVF 8990

Query: 1988 IDASTAI-DAPSNLRFLATT---PNSLLVSWQPP----RARITGYII 2026
             +    + D PS  R LA T     S  ++W  P     + IT Y+I
Sbjct: 8991 RNVHVEVYDRPSPPRNLAVTDIKAESCYLTWDAPLDNGGSEITHYVI 9037



 Score = 93.2 bits (230), Expect = 3e-18
 Identities = 379/1860 (20%), Positives = 656/1860 (35%), Gaps = 386/1860 (20%)

Query: 624   NSHPIQWNAPQPSHISKYILRW---RPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQ 680
             N+  I+W  P     SK I  W   + +N++   KE  +P    +Y + GL  G+ Y+ +
Sbjct: 22358 NAMSIRWEEPYHDGGSKIIGYWVEKKERNTILWVKENKVPCLECNYKVTGLVEGLEYQFR 22417

Query: 681   LISIQQYGHQEVTRFDFTTTSTSTPVTS-NTVTGETTPFSPLVATSESVTEITASSFVVS 739
               ++   G  + +         S P+ + N V     P          VT++T S+  + 
Sbjct: 22418 TYALNAAGVSKASE-------ASRPIMAQNPVDAPGRP---------EVTDVTRSTVSLI 22461

Query: 740   WVSAS----DTVSGFRVEYELSEEGDEPQYLDLPSTATSVN---IPDLLPGRKYIVNVYQ 792
             W + +      V G+ +E +   E  + ++L    T  S N   +  L  G  Y   V  
Sbjct: 22462 WSAPAYDGGSKVVGYIIERKPVSEVGDGRWLKCNYTIVSDNFFTVTALSEGDTYEFRVLA 22521

Query: 793   ISEDGEQSLILSTSQTTAPD------APPDPTVD-QVDDTSIVVRWSRPQAPITGYRIVY 845
              +  G   +I   S++T P       APP   +D ++    + +R         G  +V 
Sbjct: 22522 KNAAG---VISKGSESTGPVTCRDEYAPPKAELDARLHGDLVTIR--------AGSDLVL 22570

Query: 846   SPSVEGS----------STELNLPETANS----------VTLSDLQPGVQYNITIYAVEE 885
               +V G             EL+L E  +           +   D     +Y +T+     
Sbjct: 22571 DAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSGKYTLTVKNASG 22630

Query: 886   NQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDV 941
              +  + +V   ++ G     TV          VT  K T+ W+ P+    + +T Y V+ 
Sbjct: 22631 TKAVSVMVKVLDSPGPCGKLTVS--------RVTQEKCTLAWSLPQEDGGAEITHYIVE- 22681

Query: 942   IPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYY-----------FKVFAVS-HGR----E 985
                        R   SR  +  V G  P ++Y            F+V AV+ +G     E
Sbjct: 22682 -----------RRETSRLNWVIVEGECPTLSYVVTRLIKNNEYIFRVRAVNKYGPGVPVE 22730

Query: 986   SKPLTAQQTTKLDAPTNL-QFVNETDSTVLVRWTPPRA----QITGYRLTVGLTRRGQPR 1040
             S+P+ A+ +  + +P  + + V      ++++WT P +    +I+ Y   V    +   R
Sbjct: 22731 SEPIVARNSFTIPSPPGIPEEVGTGKEHIIIQWTKPESDGGNEISNY--LVDKREKKSLR 22788

Query: 1041  QYNVGPSVSKYPLR----NLQPASEYTVSLVAIK--GNQESPKATGVFTTLQPGSSIPPY 1094
                V      Y  R    +L    +Y   + A+   GN E  +A+   +  +P       
Sbjct: 22789 WTRVNKDYVVYDTRLKVTSLMEGCDYQFRVTAVNAAGNSEPSEASNFISCREP------- 22841

Query: 1095  NTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTP----GVEYV 1150
                        ++TP P         PS    APR V +   SI ++   P    G + V
Sbjct: 22842 -----------SYTPGP---------PS----APRVVDTTKHSISLAWTKPMYDGGTDIV 22877

Query: 1151  -YTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRIT 1209
              Y +++    QE+D     +V          H  A       T+     T PD+      
Sbjct: 22878 GYVLEM----QEKDTDQWYRV----------HTNA-------TIRNTEFTVPDLK----- 22911

Query: 1210  TTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPEVPQ 1269
                  GQ+ +     V+    S          EY+ S+  ++      P+    IP++  
Sbjct: 22912 ----MGQKYSFRVAAVNVKGMS----------EYSESIAEIE------PVERIEIPDLEL 22951

Query: 1270  LTDLSFVDITDSSIGLRWTPLNSSTIIGYRITVVA-AGEGIPIFEDFVDSSVGYYTVTGL 1328
               DL       +   LR       ++ G    V+  + +GI +    +  +   Y++  +
Sbjct: 22952 ADDLKKTVTIRAGASLRLMV----SVSGRPPPVITWSKQGIDLASRAIIDTTESYSLLIV 23007

Query: 1329  EPGIDYDISVITLI---NGGESAPTTLTQQTAVPPPT-DLRFTNIGPDTMRVTWAPPPSI 1384
             +    YD    T+      G+ + T L +    P P   ++   +  D++ +TW  P +I
Sbjct: 23008 DKVNRYDAGKYTIEAENQSGKKSATVLVKVYDTPGPCPSVKVKEVSRDSVTITWEIP-TI 23066

Query: 1385  DLTNFLVRYSPVKNEEDVAE---LSISPSDNAVVLTNLLPGTEYVVSV--SSVY---EQH 1436
             D    +  Y   K E  +     ++   S     ++ L+ GT Y   V   ++Y   E  
Sbjct: 23067 DGGAPVNNYIVEKREAAMRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYGIGEPC 23126

Query: 1437  ESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRP 1492
             E++      +  L  P  ++  D+T ++ T+ W  P     + +TGY +       +G  
Sbjct: 23127 ETSDAVLVSEVPL-VPAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACK---AGTE 23182

Query: 1493  REDRVPHSRNSI---TLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVP-RDLEVV 1548
             R  +V   + ++   T+T+L  G +Y+  I A N +  S      + TV+ V  +DL V+
Sbjct: 23183 RWMKVVTLKPTVLEHTVTSLNEGEQYLFRIRAQNEKGVSE----PRETVTAVTVQDLRVL 23238

Query: 1549  AATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKS---------------- 1592
                  S +          R   +     G   P   +   GSK                 
Sbjct: 23239 PTIDLSTMPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAK 23298

Query: 1593  -TATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQ----MQVTDVQDN 1647
              T   + ++   +YT+ +  VTG      +S+ I +     +DKP      +++ ++   
Sbjct: 23299 LTIRETTIRDTGEYTLELKNVTG-----TTSETIKVII---LDKPGPPTGPIKIDEIDAT 23350

Query: 1648  SISVKWLP----SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSV 1703
             SI++ W P      +P++GY V     + PG      +    T      L    EYV  V
Sbjct: 23351 SITISWEPPELDGGAPLSGYVVEQRDAHRPGWLPVSESVTRST-FKFTRLTEGNEYVFRV 23409

Query: 1704  YAQNPSGESQPL------VQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQ----GQVSRY 1753
              A N  G    L       ++++     P+ L   DV  D + + W  P+     QV+ Y
Sbjct: 23410 AATNRFGIGSYLQSEVIECRSSIRIPGPPETLQIFDVSRDGMTLTWYPPEDDGGSQVTGY 23469

Query: 1754  RVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALH------DDMESQPLIG 1807
              V                          GL  G EY   V A++          S+P++ 
Sbjct: 23470 IVERKEVRADRWVRVNKVPVTMTRYRSTGLTEGLEYEHRVTAINARGSGKPSRPSKPIVA 23529

Query: 1808  TQSTAIPA-PTDLKFTQVTPTSLSAQWTPPNVQ----LTGYRVRVTPKEKTGPMKEINLA 1862
                 A P  P + + T  T TS+S  W+ P  +    +TGY + +   ++    K     
Sbjct: 23530 MDPIAPPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTKCNTTP 23589

Query: 1863  PDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQ--GVVTTLENVSPP---------RRA 1911
                    ++ L    +Y   V A        PA+  G V   E +  P            
Sbjct: 23590 TKIREYTLTHLPQGAEYRFRVLACNAGGPGEPAEVPGTVKVTEMLEYPDYELDERYQEGI 23649

Query: 1912  RVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGT--D 1969
              V       +TI  + K      F +      GQ   +R +     ++T   ++     D
Sbjct: 23650 FVRQGGVIRLTIPIKGKP-----FPICKWTKEGQDISKRAMIATSETHTELVIKEADRGD 23704

Query: 1970  YKIYLYTLNDNARSSPVVIDASTAIDAPSN----LRFLATTPNSLLVSWQPPR----ARI 2021
                Y   L +      V I     I +P++    L +      S+ VSW+PP     A I
Sbjct: 23705 SGTYDLVLENKCGKKAVYIKVRV-IGSPNSPEGPLEYDDIQVRSVRVSWRPPADDGGADI 23763

Query: 2022  TGYII-KYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRK 2080
              GYI+ + E P +    +  R R   T   + GL+   EY   V A      S+PL   +
Sbjct: 23764 LGYILERREVPKAAWYTIDSRVRG--TSLVVKGLKENVEYHFRVSAENQFGISKPLKSEE 23821

Query: 2081  KTVQKTPFVTHPGYDTGNGIQLPGTSGQQPSVGQQMIFEEHGFRRTTPPTTATPIRHRPR 2140
                 KTP                                        PP         P 
Sbjct: 23822 PVTPKTPL--------------------------------------NPP--------EPP 23835

Query: 2141  PYPPNVGQEALSQTTISWAPFQD-----TSEYIISCHPVGTDEEPLQFRVPGTSTSATLT 2195
               PP V     S  ++SW+  +D      + Y I      TD+     +   T+T  T+T
Sbjct: 23836 SNPPEVLDVTKSSVSLSWSRPKDDGGSRVTGYYIERKETSTDKWVRHNKTQITTTMYTVT 23895

Query: 2196  GLTRGATYNIIVEALKD---QQRHKVREEVVTVGNSVNEGLNQPTDDSCFDPYTVSHYAV 2252
             GL   A Y   + A  D    +     E VV       +  ++P+     +  ++S  +V
Sbjct: 23896 GLVPDAEYQFRIIAQNDVGLSETSPASEPVV-----CKDPFDKPSQPGELEILSISKDSV 23950

Query: 2253  GDEWERMSESGFKLLCQCLGFGSGHFRCDSSRWCHDNGVNYKIGEKWDRQGENGQMMSCT 2312
               +WE+    G K   + LG+   + +   S W   N    K     D+Q   G ++  T
Sbjct: 23951 TLQWEKPECDGGK---EILGYWVEYRQSGDSAWKKSNKERIK-----DKQFTIGGLLEAT 24002



 Score = 90.5 bits (223), Expect = 2e-17
 Identities = 317/1530 (20%), Positives = 556/1530 (36%), Gaps = 208/1530 (13%)

Query: 728   VTEITASSFVVSW----VSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPG 783
             +T+I+ +S  +SW          ++G+ VE     +G   +      T T   I  L   
Sbjct: 20279 ITDISKNSVSLSWQQPAFDGGSKITGYIVERRDLPDGRWTKASFTNVTETQFIISGLTQN 20338

Query: 784   RKYIVNVYQISEDGEQSLILSTSQTTAP----DAPPDPTVDQVDDTSIVVRWS-----RP 834
              +Y   V+  +  G    I + S+   P    D+   P +D   + + VV++      + 
Sbjct: 20339 SQYEFRVFARNAVGS---ISNPSEVVGPITCIDSYGGPVIDLPLEYTEVVKYRAGTSVKL 20395

Query: 835   QAPITGYRIVYSPSVEGSSTELNLPETA-----NSVTLSDL--QPGVQYNITIYAVEENQ 887
             +A I+G     +P++E    +  L   A     N+  L+ +  +   + N   Y ++   
Sbjct: 20396 RAGISGKP---APTIEWYKDDKELQTNALVCVENTTDLASILIKDADRLNSGCYELKLRN 20452

Query: 888   E--STPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDV 941
                S    I+ +    P     P    ++F  VT  K+T++W PP     + +T Y V+ 
Sbjct: 20453 AMGSASATIRVQILDKPG----PPGGPIEFKTVTAEKITLLWRPPADDGGAKITHYIVEK 20508

Query: 942   -----IPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTK 996
                  +  ++  EH +   I+       T +  G  Y F+V AV+     +PL +     
Sbjct: 20509 RETSRVVWSMVSEHLEECIIT------TTKIIKGNEYIFRVRAVNKYGIGEPLESDSVVA 20562

Query: 997   LDA-----PTNLQFVNE-TDSTVLVRWTPPRAQ----ITGYRLTVGLTRR-GQPRQYNVG 1045
              +A     P  +  V + T +++ V W+ P A     I+GY L     +  G  +     
Sbjct: 20563 KNAFVTPGPPGIPEVTKITKNSMTVVWSRPIADGGSDISGYFLEKRDKKSLGWFKVLKET 20622

Query: 1046  PSVSKYPLRNLQPASEYTVSLVAIKGNQESP--KATGVFTTLQP-GSSIPPYNTEVTETT 1102
                ++  +  L   S+Y   + A+    + P  + +  +    P     PP    + ++T
Sbjct: 20623 IRDTRQKVTGLTENSDYQYRVCAVNAAGQGPFSEPSEFYKAADPIDPPGPPAKIRIADST 20682

Query: 1103  ---IVITWTP------APRIGFKLGVRPSQGGEAPREVTSDSGSI-----VVSGLTPGVE 1148
                I + W+       +   G+ + +R  QG E      S  G +     VVS L PGV 
Sbjct: 20683 KSSITLGWSKPVYDGGSAVTGYVVEIR--QGEEEEWTTVSTKGEVRTTEYVVSNLKPGVN 20740

Query: 1149  YVYTIQVLRDGQERDAPIVNKVVTP---LSPP---------TNLHLEANPDTGVL----- 1191
             Y + +  +    + +   +N+ V     L  P         T++  +A  D  VL     
Sbjct: 20741 YYFRVSAVNCAGQGEPIEMNEPVQAKDILEAPEIDLDVALRTSVIAKAGEDVQVLIPFKG 20800

Query: 1192  ----TVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSV 1247
                 TV+W +      +  R +   T+     ++ +V   D             +Y +++
Sbjct: 20801 RPPPTVTWRKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTG-----------KYILTI 20849

Query: 1248  YTVKDDKESVPISDTIIPEVPQLTDLSFVDITDSSIGLRWTPL---NSSTIIGYRITVVA 1304
                  + +S  +S  ++        L    ++  ++ L W P      S II Y I    
Sbjct: 20850 ENGVGEPKSSTVSVKVLDTPAACQKLQVKHVSRGTVTLLWDPPLIDGGSPIINYVIEKRD 20909

Query: 1305  AGEGIPIFEDFVDSSVGYYTVTGLEPG-IDYDISVITLINGGESAPTTLTQQTA-VPPPT 1362
             A +          SS  +  +   E     + +     I  GE   TT   + A VP P 
Sbjct: 20910 ATKRTWSVVSHKCSSTSFKLIDLSEKTPFFFRVLAENEIGIGEPCETTEPVKAAEVPAPI 20969

Query: 1363  -DLRFTNIGPDTMRVTWAPPP---SIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTN 1418
              DL   +    ++ ++W  P       +T ++V     K E+  +   IS +   + ++ 
Sbjct: 20970 RDLSMKDSTKTSVILSWTKPDFDGGSVITEYVVERKG-KGEQTWSHAGISKTCE-IEVSQ 21027

Query: 1419  LLPGTEYVVSVSSVYEQHESTPLRGRQKT--GLDSPTGIDFSDITANSFTVHWIAPRATI 1476
             L   +     V +  E+  S P+     T   L     +D SDI     TV         
Sbjct: 21028 LKEQSVLEFRVFAKNEKGLSDPVTIGPITVKELIITPEVDLSDIPGAQVTVR-------- 21079

Query: 1477  TGYRIRHHPEHFSGRPRED----------------RVPHSRNSITLT----NLTPGTEYV 1516
              G+ + H    + G+P+                  R   + N ITL+        G +Y 
Sbjct: 21080 IGHNV-HLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGGKYT 21138

Query: 1517  VSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVT----VRYYRIT 1572
             V +     R   P+ +      S     +        S+++SWD P       +  Y I 
Sbjct: 21139 VILDNAVCRIAVPITVITLGPPSKPKGPIRFDEIKADSVILSWDVPEDNGGGEITCYSIE 21198

Query: 1573  YGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDS-PASSKPISINYRT 1631
               ET   +  +      +++T  +  L    +Y   V A    G S P  S  I   ++ 
Sbjct: 21199 KRETSQTN-WKMVCSSVARTTFKVPNLVKDAEYQFRVRAENRYGVSQPLVSSIIVAKHQF 21257

Query: 1632  EID-KPSQMQVTDVQDNSISVKW----LPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQT 1686
              I   P +  + +V  + +S+ W        S VTG+ V    +N     K  T+     
Sbjct: 21258 RIPGPPGKPVIYNVTSDGMSLTWDAPVYDGGSEVTGFHVEKKERNSILWQKVNTSPISGR 21317

Query: 1687  EMTIEGLQPTVEYVVSVYAQNPSGESQPLVQT----AVTNIDRPKGLAFTDVDVDSIKIA 1742
             E    GL   ++Y   VYA+N +G S P   +    AV+ +D P    + DV  ++I + 
Sbjct: 21318 EYRATGLVEGLDYQFRVYAENSAGLSSPSDPSKFTLAVSPVDPPGTPDYIDVTRETITLK 21377

Query: 1743  WESPQGQVSRYRVTYSSPEDGIHELFPA---PDGEEDTAELQGLRPGSEYTVSVVALHDD 1799
             W  P        V YS  +   +E +      D  E    + GL PG  Y   ++A +  
Sbjct: 21378 WNPPLRDGGSKIVGYSIEKRQGNERWVRCNFTDVSECQYTVTGLSPGDRYEFRIIARNAV 21437

Query: 1800  MESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEI 1859
                 P   +QS+ I    D     +       ++    +  +G  +R+    +  P+  +
Sbjct: 21438 GTISP--PSQSSGIIMTRDENVPPIV--EFGPEYFDGLIIKSGESLRIKALVQGRPVPRV 21493

Query: 1860  NLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTT-LENVSPPRRARV-TDAT 1917
                 D   +     M  T    S        T R  +GV T   +N S   +A +     
Sbjct: 21494 TWFKDGVEIEKRMNMEITDVLGSTSLFVRDAT-RDHRGVYTVEAKNASGSAKAEIKVKVQ 21552

Query: 1918  ETTITISWRTKTETITGFQV----DAVPANGQTPIQRTI----------------KPDVR 1957
             +T   +    +   ITG ++    DA   +G  PI   I                K + +
Sbjct: 21553 DTPGKVVGPIRFTNITGEKMTLWWDAPLNDGCAPITHYIIEKRETSRLAWALIEDKCEAQ 21612

Query: 1958  SYTITGLQPGTDYKIYLYTLNDNA-----RSSPVVIDAS-TAIDAPSNLRFLATTPNSLL 2011
             SYT   L  G +Y+  +  +N         S PVV     T  DAP        T NS+ 
Sbjct: 21613 SYTAIKLINGNEYQFRVSAVNKFGVGRPLDSDPVVAQIQYTVPDAPGIPEPSNITGNSIT 21672

Query: 2012  VSWQPPRA----RITGYII-KYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIA 2066
             ++W  P +     I  YI+ + EK  +   +V+ +     T   +TGL  G EY  +V+A
Sbjct: 21673 LTWARPESDGGSEIQQYILERREKKSTRWVKVISKRPISETRFKVTGLTEGNEYEFHVMA 21732

Query: 2067  LKNNQKSEPLIGRKKTVQKTPFVTHPGYDT 2096
              +N     P  G  + ++    V  PG  T
Sbjct: 21733 -ENAAGVGPASGISRLIKCREPVNPPGPPT 21761



 Score = 90.1 bits (222), Expect = 2e-17
 Identities = 348/1626 (21%), Positives = 567/1626 (34%), Gaps = 224/1626 (13%)

Query: 624   NSHPIQWNAPQ---PSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKG--LKPGVVYE 678
             +S  + W  P+    S I+ YI+  R   S   W+   +   +   TIK   LK G  Y+
Sbjct: 15759 DSITLSWGPPKYDGGSSINNYIVEKRD-TSTTTWQ--IVSATVARTTIKACRLKTGCEYQ 15815

Query: 679   GQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVV 738
              ++ +  +YG       + T       V          P +P+V  S      +  S  V
Sbjct: 15816 FRIAAENRYGKSTYLNSEPTVAQYPFKVPG-------PPGTPVVTLS------SRDSMEV 15862

Query: 739   SWVSASDTVSGFRVEYELS-EEGDEPQYLDL---PSTATSVNIPDLLPGRKYI--VNVYQ 792
              W           + Y L  +E +   ++ L   P   T      L  G +Y   V+   
Sbjct: 15863 QWNEPISDGGSRVIGYHLERKERNSILWVKLNKTPIPQTKFKTTGLEEGVEYEFRVSAEN 15922

Query: 793   ISEDGEQSLILSTSQTTAPDAPPD-PTVDQVDDTSIVVRWSRPQ----APITGYRIVYSP 847
             I   G+ S +        P  PP  P    V   S+ ++W +P     + ITGY +    
Sbjct: 15923 IVGIGKPSKVSECYVARDPCDPPGRPEAIIVTRNSVTLQWKKPTYDGGSKITGYIVEKKE 15982

Query: 848   SVEG---SSTELNLPETANSVTLSDLQPGVQYNITIYA------VEENQESTPVVIQQET 898
               EG    ++  N+ +T   VT   L    +Y   + A        E  EST  +  ++ 
Sbjct: 15983 LPEGRWMKASFTNIIDTHFEVT--GLVEDHRYEFRVIARNAAGVFSEPSESTGAITARDE 16040

Query: 899   TGTPRSDTVPSPRDLQFVEVTD---VKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRLP 955
                PR    P  +D   V   +   V   I   P  +      +  I  +    +  RL 
Sbjct: 16041 VDPPRISMDPKYKDTIVVHAGESFKVDADIYGKPIPT------IQWIKGDQELSNTARLE 16094

Query: 956   ISRNTFAEVTGLSPGV-----TYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNE-T 1009
             I    FA    +   V      Y  K   V+ G  S  +  +   +   P     ++  T
Sbjct: 16095 IKSTDFATSLSVKDAVRVDSGNYILKAKNVA-GERSVTVNVKVLDRPGPPEGPVVISGVT 16153

Query: 1010  DSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVS 1065
                  + W PP     + I  Y +    T R      +         +  L   +EYT  
Sbjct: 16154 AEKCTLAWKPPLQDGGSDIINYIVERRETSRLVWTVVDANVQTLSCKVTKLLEGNEYTFR 16213

Query: 1066  LVAIKGNQ-----ESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWT-PAPR-----IG 1114
             ++A+         ES         + P +   P  T VT+ ++++ W  PA       +G
Sbjct: 16214 IMAVNKYGVGEPLESEPVVAKNPFVVPDAPKAPEVTTVTKDSMIVVWERPASDGGSEILG 16273

Query: 1115  FKLGVRPSQGGEAPREVTSDSGSIV--VSGLTPGVEYVYTIQVLRD-GQERDAP--IVNK 1169
             + L  R  +G    R      G +   V+GL    +Y + +      G    +P     K
Sbjct: 16274 YVLEKRDKEGIRWTRCHKRLIGELRLRVTGLIENHDYEFRVSAENAAGLSEPSPPSAYQK 16333

Query: 1170  VVTPL---SPPTNLHLEANPDTGVLTVSWERSTTP---DITGYRITTTPTNGQQGNSLEE 1223
                P+    PP N  +     + V  +SW +       +I GY +     +  +      
Sbjct: 16334 ACDPIYKPGPPNNPKVIDITRSSVF-LSWSKPIYDGGCEIQGYIVEKCDVSVGEWTMCTP 16392

Query: 1224  VVHADQSSCTFDNLSPGLEYNVSVYTVKD----DKESVPISDTIIPEVPQLTDLSFVDIT 1279
                 ++++   + L    EYN  +  +      +   VP    I+ E  +  D+      
Sbjct: 16393 PTGINKTNIEVEKLLEKHEYNFRICAINKAGVGEHADVP-GPIIVEEKLEAPDI------ 16445

Query: 1280  DSSIGLRWTPLNSSTIIGYRITVVAAGEGIP----------IFEDFVDSSVGYYTVTGLE 1329
             D  + LR   +N       R+ V   G   P          I +  +      +T   L+
Sbjct: 16446 DLDLELRKI-INIRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTSSFTSLVLD 16504

Query: 1330  PGIDYDISVITLI----NGGESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAPPPSID 1385
                 YD    TL     +G +SA  T+       PP +L+ T I  D++ +TW  PP +D
Sbjct: 16505 NVNRYDSGKYTLTLENSSGTKSAFVTVRVLDTPSPPVNLKVTEITKDSVSITW-EPPLLD 16563

Query: 1386  LTNFLVRYSPVKNE---EDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLR 1442
               + +  Y   K E   +  A +  +   N+  +  L  G  Y   V++  E     P +
Sbjct: 16564 GGSKIKNYIVEKREATRKSYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAENEYGIGLPAQ 16623

Query: 1443  GRQKTGL----DSPTGIDFSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGRPRE 1494
                   +      P  I   D+T NS ++ W  P     + I  Y +    +H       
Sbjct: 16624 TADPIKVAEVPQPPGKITVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKHSEKWSEC 16683

Query: 1495  DRVPHSRNSITLTNLTPGTEYVVSIVALNGREES-PLLIGQQSTVSDVPRDLEVVAA-TP 1552
              RV   +    +TNLT G EY+  +VA+N +  S P  +       D+  + +V  A + 
Sbjct: 16684 ARVKSLQ--AVITNLTQGEEYLFRVVAVNEKGRSDPRSLAVPIVAKDLVIEPDVKPAFSS 16741

Query: 1553  TSLLISWD----APAVTVRYYRITYGETGGNSPVQEFT---VPGSKSTATIS----GLKP 1601
              S+ +  D     P        IT+ + G   P+++ T   V  S    T+S        
Sbjct: 16742 YSVQVGQDLKIEVPISGRPKPTITWTKDG--LPLKQTTRINVTDSLDLTTLSIKETHKDD 16799

Query: 1602  GVDYTITVYAVTGRGDSPASSKPISINYRTEIDKP----SQMQVTDVQDNSISVKWLP-- 1655
             G  Y ITV  V G+       K  SI   T +DKP      ++  DV   SI++ W P  
Sbjct: 16800 GGQYGITVANVVGQ-------KTASIEIVT-LDKPDPPKGPVKFDDVSAESITLSWNPPL 16851

Query: 1656  --SSSPVTGYRV-----TTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNP 1708
                   +T Y V     TTT  +    T  +T       + +  L+   EY   ++A+N 
Sbjct: 16852 YTGGCQITNYIVQKRDTTTTVWDVVSATVARTT------LKVTKLKTGTEYQFRIFAENR 16905

Query: 1709  SG-----ESQPLVQTAVTNIDRPKGLAF-TDVDVDSIKIAWESPQGQVSRYRVTYSSPED 1762
              G     ES P+V         P G  F T +  DS+ I W  P        + Y     
Sbjct: 16906 YGQSFALESDPIVAQYPYKEPGPPGTPFATAISKDSMVIQWHEPVNNGGSPVIGYHLERK 16965

Query: 1763  GIHELFPAPDGE---EDTA-ELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTD 1818
               + +      +    DT  + Q L  G EY   V A +     +    ++      P D
Sbjct: 16966 ERNSILWTKVNKTIIHDTQFKAQNLEEGIEYEFRVYAENIVGVGKASKNSECYVARDPCD 17025

Query: 1819  LKFT----QVTPTSLSAQWTPP----NVQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVV 1870
                T     V    ++ QWT P       +TGY V          MK        +   V
Sbjct: 17026 PPGTPEPIMVKRNEITLQWTKPVYDGGSMITGYIVEKRDLPDGRWMKASFTNVIETQFTV 17085

Query: 1871  SGLMVATKYEVSVYALKDT-LTSRPAQ--GVVTTLENVSPPRRARVTDATETTITISWRT 1927
             SGL    +YE  V A       S+P+   G +T  + V  PR +      +T +  +  T
Sbjct: 17086 SGLTEDQRYEFRVIAKNAAGAISKPSDSTGPITAKDEVELPRISMDPKFRDTIVVNAGET 17145

Query: 1928  KTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQ-PGTDYKIYL------------ 1974
                    F+++A       P    ++ D         +   TD+K  L            
Sbjct: 17146 -------FRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRIDGGQ 17198

Query: 1975  YTLNDN----ARSSPV---VIDASTAIDAPSNLRFLATTPNSLLVSWQPP----RARITG 2023
             Y L  +    ++S PV   V+D     + P  ++    T     ++W PP     + I+ 
Sbjct: 17199 YILRASNVAGSKSFPVNVKVLDRPGPPEGP--VQVTGVTSEKCSLTWSPPLQDGGSDISH 17256

Query: 2024  YIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTV 2083
             Y+++ ++  S     V           +T L  G EY   ++A+      EPL      +
Sbjct: 17257 YVVE-KRETSRLAWTVVASEVVTNSLKVTKLLEGNEYVFRIMAVNKYGVGEPL-ESAPVL 17314

Query: 2084  QKTPFV 2089
              K PFV
Sbjct: 17315 MKNPFV 17320



 Score = 88.2 bits (217), Expect = 9e-17
 Identities = 167/815 (20%), Positives = 297/815 (36%), Gaps = 113/815 (13%)

Query: 1342  INGGESAPTTL-TQQTAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEE 1400
             + G +S P T+       PP   L+ T +  +   + W PP      N        +   
Sbjct: 18289 VGGTKSIPITVKVLDRPGPPEGPLKVTGVTAEKCYLAWNPPLQDGGANISHYIIEKRETS 18348

Query: 1401  DVAELSISPSDNAV--VLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLD------SP 1452
              ++   +S    A+   +T LLPG EY+  V +V +     PL     T  +       P
Sbjct: 18349 RLSWTQVSTEVQALNYKVTKLLPGNEYIFRVMAVNKYGIGEPLESGPVTACNPYKPPGPP 18408

Query: 1453  TGIDFSDITANSFTVHWIAP----RATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTN 1508
             +  + S IT +S  V W  P       I GY +    +      + ++   +   + +T 
Sbjct: 18409 STPEVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDKEGVRWTKCNKKTLTDLRLRVTG 18468

Query: 1509  LTPGTEYVVSIVALN----GREESPLLIGQQSTV---SDVPRDLEVVAATPTSLLISWDA 1561
             LT G  Y   + A N    G    P +  +          P + +V   + +S+ ++W  
Sbjct: 18469 LTEGHSYEFRVAAENAAGVGEPSEPSVFYRACDALYPPGPPSNPKVTDTSRSSVSLAWSK 18528

Query: 1562  PAVTVRYYRITYGETGGNSPVQEFTVPGSKSTA-----------------TISGLKPGVD 1604
             P               G +PV+ + V   ++ A                 T++ LK   +
Sbjct: 18529 PIY------------DGGAPVKGYVVEVKEAAADEWTTCTPPTGLQGKQFTVTKLKENTE 18576

Query: 1605  YTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYR 1664
             Y   + A+   G    ++ P S+  +  I+ P      D++     V  L +S+ +   R
Sbjct: 18577 YNFRICAINSEGVGEPATLPGSVVAQERIEPPEIELDADLR----KVVVLRASATL---R 18629

Query: 1665  VTTTPKNGPGP----TKTKTAGPD--QTEMTIEGLQPTVEYVV-------SVYAQNPSGE 1711
             +  T K  P P     K +    D  Q E+T       ++ V        ++  +N SG 
Sbjct: 18630 LFVTIKGRPEPEVKWEKAEGILTDRAQIEVTSSFTMLVIDNVTRFDSGRYNLTLENNSGS 18689

Query: 1712  SQPLVQTAVTNI-DRPKGLAFTDVDVDSIKIAWESP----QGQVSRYRVTYSSPEDGIHE 1766
                 V   V +    P  L   +V  DS+ ++WE P      +++ Y V         + 
Sbjct: 18690 KTAFVNVRVLDSPSAPVNLTIREVKKDSVTLSWEPPLIDGGAKITNYIVEKRETTRKAYA 18749

Query: 1767  LFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPT----DLKFT 1822
                  +  + T  ++ L+ G  Y   V+A ++     P   T+   +  P      +   
Sbjct: 18750 TI-TNNCTKTTFRIENLQEGCSYYFRVLASNEYGIGLPAETTEPVKVSEPPLPPGRVTLV 18808

Query: 1823  QVTPTSLSAQWTPP----NVQLTGYRVRVTPK--EKTGPMKEINLAPDSSSVVVSGLMVA 1876
              VT  + + +W  P      ++TGY V +  K  EK     ++     +    +SGL   
Sbjct: 18809 DVTRNTATIKWEKPESDGGSKITGYVVEMQTKGSEKWSTCTQVK----TLEATISGLTAG 18864

Query: 1877  TKYEVSVYALKDTLTSRPAQ-GVVTTLENVS-------PPRRARVTDATETTITISWRTK 1928
              +Y   V A+ +   S P Q GV     ++        P     V    +  I + ++ +
Sbjct: 18865 EEYVFRVAAVNEKGRSDPRQLGVPVIARDIEIKPSVELPFHTFNVKAREQLKIDVPFKGR 18924

Query: 1929  TETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQ----PGTDYKIYLYTLNDNARS- 1983
              +    ++ D     GQT  + T      S T+T L        D   Y   ++++A S 
Sbjct: 18925 PQATVNWRKD-----GQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSNSAGSI 18979

Query: 1984  -SPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREV 2038
               P+ I        P  +R    + +S+ +SW PP      +I+ YI++ ++  S    +
Sbjct: 18980 TVPITIIVLDRPGPPGPIRIDEVSCDSITISWNPPEYDGGCQISNYIVEKKETTSTTWHI 19039

Query: 2039  VPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKS 2073
             V +     T   I  L  G+EY   V A     KS
Sbjct: 19040 VSQ-AVARTSIKIVRLTTGSEYQFRVCAENRYGKS 19073



 Score = 86.3 bits (212), Expect = 3e-16
 Identities = 342/1651 (20%), Positives = 590/1651 (35%), Gaps = 266/1651 (16%)

Query: 628   IQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISI 684
             + W+ P+    S I+ +I+  R    +  W++  I    +   I GL  G  Y+ ++I+ 
Sbjct: 8718  LNWSDPEDDGGSEITGFIIE-RKDAKMHTWRQP-IETERSKCDITGLLEGQEYKFRVIAK 8775

Query: 685   QQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWV--- 741
              ++G                PV    +        P      + TE T S+  + W    
Sbjct: 8776  NKFG-------------CGPPVEIGPILAVDPLGPPTSPERLTYTERTKSTITLDWKEPR 8822

Query: 742   -SASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQS 800
              +    + G+ +E    ++ D  +        TS  + +L   + Y   V  ++E GE  
Sbjct: 8823  SNGGSPIQGYIIEKRRHDKPDFERVNKRLCPTTSFLVENLDEHQMYEFRVKAVNEIGESE 8882

Query: 801   LILSTSQTTAPDAPPDPTVD---QVDDTSIVVRWSRP---QAPITGYRIVYSPSVEGSST 854
               L  +     D  P PT+     V   +I V+   P    A +TG  +   P +E S  
Sbjct: 8883  PSLPLNVVIQDDEVP-PTIKLRLSVRGDTIKVKAGEPVHIPADVTGLPM---PKIEWSKN 8938

Query: 855   E--LNLPETANSVTLSDLQPG-VQYNITI-YAVEENQESTPVVIQQETTGTPRS------ 904
             E  +  P  A  +T  ++     +  ++I  AV E++ +  V          R+      
Sbjct: 8939  ETVIEKPTDALQITKEEVSRSEAKTELSIPKAVREDKGTYTVTASNRLGSVFRNVHVEVY 8998

Query: 905   DTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPGEHGQRLPISRNT 960
             D    PR+L   ++      + W  P     S +T Y +D    +      + +    NT
Sbjct: 8999  DRPSPPRNLAVTDIKAESCYLTWDAPLDNGGSEITHYVIDKRDASRKKAEWEEVT---NT 9055

Query: 961   FAE----VTGLSPGVTYYFKV-----FAVSHGRESKPLTAQQTTKLDAPTNL-QFVNETD 1010
               E    +  L P   Y F+V     + +S   +S  +  Q   +L  P    + +  T 
Sbjct: 9056  AVEKRYGIWKLIPNGQYEFRVRAVNKYGISDECKSDKVVIQDPYRLPGPPGKPKVLARTK 9115

Query: 1011  STVLVRWTPP----RAQITGYRLTVGLTRRGQPRQY----------NVGPSVSKYPLRNL 1056
              ++LV WTPP     + ITGY     L +R +   Y           VG    ++ +  L
Sbjct: 9116  GSMLVSWTPPLDNGGSPITGY----WLEKREEGSPYWSRVSRAPITKVGLKGVEFNVPRL 9171

Query: 1057  QPASEYTVSLVAIKG------NQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPA 1110
                 +Y    +AI        ++ S           PG    P   + T+++I + W P 
Sbjct: 9172  LEGVKYQFRAMAINAAGIGPPSEPSDPEVAGDPIFPPGPPSCPEVKDKTKSSISLGWKPP 9231

Query: 1111  PRIGFKLGVRPSQG--GEAPREVTSD------------SGSIVVSGLTPGVEYVYTIQVL 1156
                  K G  P +G   E   E T+D            +   VV  L    +Y + ++ +
Sbjct: 9232  A----KDGGSPIKGYIVEMQEEGTTDWKRVNEPDKLITTCECVVPNLKELRKYRFRVKAV 9287

Query: 1157  RD-GQERDAPIVNKV-VTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPT- 1213
              + G+   +    ++  T +     + ++      ++  +  +   P +   R T   + 
Sbjct: 9288  NEAGESEPSDTTGEIPATDIQEEPEVFIDIGAQDCLVCKAGSQIRIPAVIKGRPTPKSSW 9347

Query: 1214  --NGQQGNSLEEVVH---ADQSSCTFDNLSPGL----------EYNVSVYTVKDDKES-- 1256
               +G+   ++++ VH    D    T +N S  +          +Y+++       K +  
Sbjct: 9348  EFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECKRSHTGKYSITAKNKAGQKTANC 9407

Query: 1257  -VPISDTIIPEVPQLTDLSFVDITDSSIGLRWTPLN---SSTIIGYRITVVAAGEGIPIF 1312
              V + D  +P  P+  DL   DIT  S  L W   +      I GY I      +G    
Sbjct: 9408  RVKVMD--VPGPPK--DLKVSDITRGSCRLSWKMPDDDGGDRIKGYVIEKRTI-DGKAWT 9462

Query: 1313  EDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAV-------PPPTDLR 1365
             +   D     + V  L     Y   V      G   P    Q+T          PP  L+
Sbjct: 9463  KVNPDCGSTTFVVPDLLSEQQYFFRVRAENRFGIGPPVETIQRTTARDPIYPPDPPIKLK 9522

Query: 1366  FTNIGPDTMRVTWAPPPS---IDLTNFLVR---YSPVK---------NEEDVAELSISPS 1410
                I  +T+ ++W PP +     +T+++V    + P           N+ DV EL  +  
Sbjct: 9523  IGLITKNTVHLSWKPPKNDGGSPVTHYIVECLAWDPTGTKKEAWRQCNKRDVEELQFTVE 9582

Query: 1411  DNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGL---DSPTGIDFSDI--TANSF 1465
             D       L+ G EY   V +V     S P            D P  ID  +        
Sbjct: 9583  D-------LVEGGEYEFRVKAVNAAGVSKPSATVGPCDCQRPDMPPSIDLKEFMEVEEGT 9635

Query: 1466  TVHWIA-----PRATITGYRIRH----------HPEHFSGRPREDR----VPHSRNSITL 1506
              V+ +A     P  T+T ++             +  H +    +D     +P SR S T 
Sbjct: 9636  NVNIVAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDT- 9694

Query: 1507  TNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAP---- 1562
                     Y ++ V   G     + +            ++  + +   + +SW  P    
Sbjct: 9695  ------GLYTITAVNNLGTASKEMRLNVLGRPGPPVGPIKFESVSADQMTLSWFPPKDDG 9748

Query: 1563  AVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRG-DSPAS 1621
                +  Y I   E    + V   + P  + T TI  L  G +Y   + A    G   P  
Sbjct: 9749  GSKITNYVIEKREANRKTWVHVSSEP-KECTYTIPKLLEGHEYVFRIMAQNKYGIGEPLD 9807

Query: 1622  SKP-ISINYRTEIDKPSQMQVTDVQDNSISVKW----LPSSSPVTGYRV---TTTPKN-- 1671
             S+P  + N  +    P +  V+ V  NS++V W        SPVTGY +    TT K   
Sbjct: 9808  SEPETARNLFSVPGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPVTGYWLEMKDTTSKRWK 9867

Query: 1672  --GPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSG---ESQPLVQTAVTNIDRP 1726
                  P K  T G       + GL    +Y   VYA N +G    S P       +   P
Sbjct: 9868  RVNRDPIKAMTLG---VSYKVTGLIEGSDYQFRVYAINAAGVGPASLPSDPATARDPIAP 9924

Query: 1727  KGLAF---TDVDVDSIKIAWESP----QGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAE 1779
              G  F   TD    S  + W  P      +V+ Y V Y   E+G  E     D E    +
Sbjct: 9925  PGPPFPKVTDWTKSSADLEWSPPLKDGGSKVTGYIVEYK--EEGKEEWEKGKDKEVRGTK 9982

Query: 1780  L--QGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTP-TSLSAQWTPP 1836
             L   GL+ G+ Y   V A++     +P  G  +  I    ++K   V+P   L A     
Sbjct: 9983  LVVTGLKEGAFYKFRVRAVNIAGIGEP--GEVTDVI----EMKDRLVSPDLQLDASVRDR 10036

Query: 1837  NVQLTGYRVRV-------TPKEKTGPMKEINLAPDSS--SVVVSGLMVATKYEVS---VY 1884
              V   G  +R+        P   T  M E  L  +++  +  +S  MV    + S   VY
Sbjct: 10037 IVVHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEATIETTAISSSMVIKNCQRSHQGVY 10096

Query: 1885  AL--KDTLTSRPAQGVVTTLENVSPPRRARVT-DATETTITISWRTKTE----TITGFQV 1937
             +L  K+    R    +V  L+   P     +  + T  +  ++W +  +     IT + +
Sbjct: 10097 SLLAKNEAGERKKTIIVDVLDVPGPVGTPFLAHNLTNESCKLTWFSPEDDGGSPITNYVI 10156

Query: 1938  DAVPANGQ--TPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLND-------NARSSPVVI 1988
             +   ++ +  TP+  T+    ++ T+ GL  G  Y   +   N            + V+ 
Sbjct: 10157 EKRESDRRAWTPVTYTVTR--QNATVQGLIQGKAYFFRIAAENSIGMGPFVETSEALVIR 10214

Query: 1989  DASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREVVPRPRP 2044
             +  T  + P +L     T N++ ++W PP+    + I  Y+++    G+     V     
Sbjct: 10215 EPITVPERPEDLEVKEVTKNTVTLTWNPPKYDGGSEIINYVLESRLIGTEKFHKVTNDNL 10274

Query: 2045  GVTEATITGLEPGTEYTIYVIALKNNQKSEP 2075
                + T+ GL+ G  Y   V A+    + +P
Sbjct: 10275 LSRKYTVKGLKEGDTYEYRVSAVNIVGQGKP 10305



 Score = 84.3 bits (207), Expect = 1e-15
 Identities = 134/644 (20%), Positives = 244/644 (37%), Gaps = 79/644 (12%)

Query: 1512  GTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAP----AVTVR 1567
             G +Y++    + G +  P+ +            ++V   T     ++W  P       + 
Sbjct: 17196 GGQYILRASNVAGSKSFPVNVKVLDRPGPPEGPVQVTGVTSEKCSLTWSPPLQDGGSDIS 17255

Query: 1568  YYRITYGETGGNSPVQEFTVPGSK---STATISGLKPGVDYTITVYAVTGRG-DSPASSK 1623
             +Y +   ET   +    +TV  S+   ++  ++ L  G +Y   + AV   G   P  S 
Sbjct: 17256 HYVVEKRETSRLA----WTVVASEVVTNSLKVTKLLEGNEYVFRIMAVNKYGVGEPLESA 17311

Query: 1624  PISINYRTEID-KPSQMQVTDVQDNSISVKW-LPSS---SPVTGYRVTTTPKNGPGPTKT 1678
             P+ +     +   P  ++VT++  +S++V W  P S   S + GY V    ++G    K 
Sbjct: 17312 PVLMKNPFVLPGPPKSLEVTNIAKDSMTVCWNRPDSDGGSEIIGYIVEKRDRSGIRWIKC 17371

Query: 1679  KTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTA-------VTNIDRPKGLAF 1731
                      + + GL    EY   V A+N +G  +P   T        V     P     
Sbjct: 17372 NKRRITDLRLRVTGLTEDHEYEFRVSAENAAGVGEPSPATVYYKACDPVFKPGPPTNAHI 17431

Query: 1732  TDVDVDSIKIAWESP----QGQVSRYRVTYSSPEDGIHELFPAPDGEEDTA-ELQGLRPG 1786
              D   +SI +AW  P      ++  Y V     ++   ++     G   T  E+  L   
Sbjct: 17432 VDTTKNSITLAWGKPIYDGGSEILGYVVEICKADEEEWQIVTPQTGLRVTRFEISKLTEH 17491

Query: 1787  SEYTVSVVALHDDMESQPLIGT-QSTAIPAPTDLKFTQVTPT-SLSAQWTPPNVQLTGYR 1844
              EY + V AL+        +G  ++T++P     +     P   L ++     V   G  
Sbjct: 17492 QEYKIRVCALNK-------VGLGEATSVPGTVKPEDKLEAPELDLDSELRKGIVVRAGGS 17544

Query: 1845  VRVTPKEKTGPMKEINLAPD----SSSVVVSGLMVATKYEVS----------VYALKDTL 1890
              R+    K  P  EI  + +    +  V +   +  T+  +           +  L+++ 
Sbjct: 17545 ARIHIPFKGRPTPEITWSREEGEFTDKVQIEKGVNYTQLSIDNCDRNDAGKYILKLENSS 17604

Query: 1891  TSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKT----ETITGFQVDAVPANGQT 1946
              S+ A   V  L+   PP+   V +  + +  + W          +  + +D   +  + 
Sbjct: 17605 GSKSAFVTVKVLDTPGPPQNLAVKEVRKDSAFLVWEPPIIDGGAKVKNYVIDKRESTRKA 17664

Query: 1947  PIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPV-VIDASTAIDAPS-----NL 2000
                 + K    S+ +  L  G  Y   +   N+     PV  +DA  A + PS      L
Sbjct: 17665 YANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFGVGVPVETVDAVKAAEPPSPPGKVTL 17724

Query: 2001  RFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEP 2056
               ++ T  SL+  W+ P     +R+ GY+++ +  G+    +V   +  V  A +TGL  
Sbjct: 17725 TDVSQTSASLM--WEKPEHDGGSRVLGYVVEMQPKGTEKWSIVAESK--VCNAVVTGLSS 17780

Query: 2057  GTEYTIYVIALKNNQKSE------PLIGRKKTVQ---KTPFVTH 2091
             G EY   V A     KS+      P+I +  T+Q   K PF T+
Sbjct: 17781 GQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQPSLKLPFNTY 17824



 Score = 83.6 bits (205), Expect = 2e-15
 Identities = 320/1617 (19%), Positives = 567/1617 (35%), Gaps = 238/1617 (14%)

Query: 628   IQWNAPQPS---HISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISI 684
             + WN P  +    I+ YI++ R   +   W   +      +  +  LK G  Y+ ++ + 
Sbjct: 16845 LSWNPPLYTGGCQITNYIVQKRDTTTTV-WDVVSATVARTTLKVTKLKTGTEYQFRIFAE 16903

Query: 685   QQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSAS 744
              +YG       D        P+ +     E  P     AT+     I+  S V+ W    
Sbjct: 16904 NRYGQSFALESD--------PIVAQYPYKEPGPPGTPFATA-----ISKDSMVIQWHEPV 16950

Query: 745   DTVSGFRVEYELS-EEGDEPQYLDLPSTA---TSVNIPDLLPG-----RKYIVNVYQISE 795
             +      + Y L  +E +   +  +  T    T     +L  G     R Y  N+  + +
Sbjct: 16951 NNGGSPVIGYHLERKERNSILWTKVNKTIIHDTQFKAQNLEEGIEYEFRVYAENIVGVGK 17010

Query: 796   DGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ----APITGYRIVYSPSVEG 851
               + S          P   P+P +  V    I ++W++P     + ITGY +      +G
Sbjct: 17011 ASKNSECYVARDPCDPPGTPEPIM--VKRNEITLQWTKPVYDGGSMITGYIVEKRDLPDG 17068

Query: 852   ---SSTELNLPETANSVTLSDLQPGVQYNITIYA------VEENQESTPVVIQQETTGTP 902
                 ++  N+ ET    T+S L    +Y   + A      + +  +ST  +  ++    P
Sbjct: 17069 RWMKASFTNVIET--QFTVSGLTEDQRYEFRVIAKNAAGAISKPSDSTGPITAKDEVELP 17126

Query: 903   RSDTVPSPRDLQFVEVTDV-----------KVTIMWTPPESAVTGYRVDVIPVNLPGEHG 951
             R    P  RD   V   +              TI W   +  +              E  
Sbjct: 17127 RISMDPKFRDTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEI--------------EES 17172

Query: 952   QRLPISRNTFAEVTGLSPGVT-----YYFKVFAVSHGRESKPLTAQQTTKLDAPTN-LQF 1005
              R  I    F  +  +   +      Y  +   V+ G +S P+  +   +   P   +Q 
Sbjct: 17173 ARCEIKNTDFKALLIVKDAIRIDGGQYILRASNVA-GSKSFPVNVKVLDRPGPPEGPVQV 17231

Query: 1006  VNETDSTVLVRWTPPR----AQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASE 1061
                T     + W+PP     + I+ Y +    T R            +   +  L   +E
Sbjct: 17232 TGVTSEKCSLTWSPPLQDGGSDISHYVVEKRETSRLAWTVVASEVVTNSLKVTKLLEGNE 17291

Query: 1062  YTVSLVAIK--GNQESPKATGVFTT---LQPGSSIPPYNTEVT---ETTIVITWTPAPR- 1112
             Y   ++A+   G  E  ++  V      + PG   PP + EVT   + ++ + W      
Sbjct: 17292 YVFRIMAVNKYGVGEPLESAPVLMKNPFVLPG---PPKSLEVTNIAKDSMTVCWNRPDSD 17348

Query: 1113  -----IGFKLGVRPSQGGE----APREVTSDSGSIVVSGLTPGVEYVYTIQVLRD---GQ 1160
                  IG+ +  R   G        R +T     + V+GLT   EY + +        G+
Sbjct: 17349 GGSEIIGYIVEKRDRSGIRWIKCNKRRITDLR--LRVTGLTEDHEYEFRVSAENAAGVGE 17406

Query: 1161  ERDAPIVNKVVTPL---SPPTNLHLEANPDTGVLTVSWERSTTP---DITGYRITTTPTN 1214
                A +  K   P+    PPTN H+  +     +T++W +       +I GY +     +
Sbjct: 17407 PSPATVYYKACDPVFKPGPPTNAHI-VDTTKNSITLAWGKPIYDGGSEILGYVVEICKAD 17465

Query: 1215  GQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDK--ESVPISDTIIPE----VP 1268
              ++   +        +      L+   EY + V  +      E+  +  T+ PE     P
Sbjct: 17466 EEEWQIVTPQTGLRVTRFEISKLTEHQEYKIRVCALNKVGLGEATSVPGTVKPEDKLEAP 17525

Query: 1269  QLTDLSFVDITDSSIGLRWTPLNSSTII--GYRITVVAAGEGIPIFEDFVDSSVGYYT-V 1325
             +L DL              + L    ++  G    +    +G P  E       G +T  
Sbjct: 17526 EL-DLD-------------SELRKGIVVRAGGSARIHIPFKGRPTPEITWSREEGEFTDK 17571

Query: 1326  TGLEPGIDYD---------------ISVITLINGGESAPTTLTQQTAVPPPTDLRFTNIG 1370
               +E G++Y                I  +   +G +SA  T+       PP +L    + 
Sbjct: 17572 VQIEKGVNYTQLSIDNCDRNDAGKYILKLENSSGSKSAFVTVKVLDTPGPPQNLAVKEVR 17631

Query: 1371  PDTMRVTWAPPPSIDLTNFLVRYSPVKNEED---VAELSISPSDNAVVLTNLLPGTEYVV 1427
              D+  + W PP  ID    +  Y   K E      A +S   S  +  + NL  G  Y  
Sbjct: 17632 KDSAFLVWEPP-IIDGGAKVKNYVIDKRESTRKAYANVSSKCSKTSFKVENLTEGAIYYF 17690

Query: 1428  SVSSVYEQHESTPLR---GRQKTGLDSPTG-IDFSDITANSFTVHWIAPR----ATITGY 1479
              V +  E     P+      +     SP G +  +D++  S ++ W  P     + + GY
Sbjct: 17691 RVMAENEFGVGVPVETVDAVKAAEPPSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLGY 17750

Query: 1480  RIRHHPEHFSGRPREDRVPHSRN-SITLTNLTPGTEYVVSIVALNGREES-PLLIGQQST 1537
              +   P+   G  +   V  S+  +  +T L+ G EY   + A N + +S P ++G    
Sbjct: 17751 VVEMQPK---GTEKWSIVAESKVCNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVI 17807

Query: 1538  VSDVPRDLEVVAATPTSLL-----ISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKS 1592
               D+     +     T  +     +  + P +      I++ + G   P+++ T    + 
Sbjct: 17808 AKDLTIQPSLKLPFNTYSIQAGEDLKIEIPVIGRPRPNISWVKDG--EPLKQTTRVNVEE 17865

Query: 1593  TAT--ISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKP-SQMQVTDVQDNSI 1649
             TAT  +  +K G       Y VT    +  +++ +S+    +   P   ++  +V  + +
Sbjct: 17866 TATSTVLHIKEGNKDDFGKYTVTATNSAGTATENLSVIVLEKPGPPVGPVRFDEVSADFV 17925

Query: 1650  SVKWLPSS----SPVTGYRV-----TTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYV 1700
              + W P +      ++ Y V     TTT  +    T  +T       + I  L+   EY 
Sbjct: 17926 VISWEPPAYTGGCQISNYIVEKRDTTTTTWHMVSATVARTT------IKITKLKTGTEYQ 17979

Query: 1701  VSVYAQNPSGESQPLVQTAVT-----NIDRPKGLAF-TDVDVDSIKIAWESPQGQVSRYR 1754
               ++A+N  G+S PL   AV          P G  F T +  D + + W  P        
Sbjct: 17980 FRIFAENRYGKSAPLDSKAVIVQYPFKEPGPPGTPFVTSISKDQMLVQWHEPVNDGGTKI 18039

Query: 1755  VTYSSPEDGIHELF-------PAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIG 1807
             + Y   +   + +        P  D +  T    GL  G EY   V A +     +P   
Sbjct: 18040 IGYHLEQKEKNSILWVKLNKTPIQDTKFKTT---GLDEGLEYEFKVSAENIVGIGKPSKV 18096

Query: 1808  TQSTAIPAPTDL----KFTQVTPTSLSAQWTPP----NVQLTGYRVRVTPKEKTGPMKEI 1859
             ++      P D     +   +T  +++ +W  P      ++TGY V          MK  
Sbjct: 18097 SECFVARDPCDPPGRPEAIVITRNNVTLKWKKPAYDGGSKITGYIVEKKDLPDGRWMKAS 18156

Query: 1860  NLAPDSSSVVVSGLMVATKYEVSVYALKDTLT-SRPAQ--GVVTTLENVSPPRRAR---- 1912
                   +   VSGL+   +YE  V A       S P+   G +T  + +  P  +     
Sbjct: 18157 FTNVLETEFTVSGLVEDQRYEFRVIARNAAGNFSEPSDSSGAITARDEIDAPNASLDPKY 18216

Query: 1913  ----VTDATET-TITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQP- 1966
                 V  A ET  +    R K      +  D      +T  +  IK  ++  T+      
Sbjct: 18217 KDVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELE-ETAARMEIKSTIQKTTLVVKDCI 18275

Query: 1967  GTDYKIYLYTLND--NARSSPVVIDASTAIDAPSN-LRFLATTPNSLLVSWQPPR----A 2019
              TD   Y+  L++    +S P+ +        P   L+    T     ++W PP     A
Sbjct: 18276 RTDGGQYILKLSNVGGTKSIPITVKVLDRPGPPEGPLKVTGVTAEKCYLAWNPPLQDGGA 18335

Query: 2020  RITGYIIKYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPL 2076
              I+ YII+  +        V      +    +T L PG EY   V+A+      EPL
Sbjct: 18336 NISHYIIEKRETSRLSWTQVSTEVQALNYK-VTKLLPGNEYIFRVMAVNKYGIGEPL 18391



 Score = 82.4 bits (202), Expect = 5e-15
 Identities = 130/589 (22%), Positives = 217/589 (36%), Gaps = 70/589 (11%)

Query: 1596  ISGLKPGVDYTITVYAVTGRG-DSPASSKPI-SINYRTEIDKPSQMQVTDVQDNSISVKW 1653
             ++ L  G +YT  + AV   G   P  S+P+ + N     D P   +VT V  +S+ V W
Sbjct: 16201 VTKLLEGNEYTFRIMAVNKYGVGEPLESEPVVAKNPFVVPDAPKAPEVTTVTKDSMIVVW 16260

Query: 1654  -LPSS---SPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPS 1709
               P+S   S + GY +    K G   T+       +  + + GL    +Y   V A+N +
Sbjct: 16261 ERPASDGGSEILGYVLEKRDKEGIRWTRCHKRLIGELRLRVTGLIENHDYEFRVSAENAA 16320

Query: 1710  GESQPLVQTA-------VTNIDRPKGLAFTDVDVDSIKIAWESP----QGQVSRYRVTYS 1758
             G S+P   +A       +     P      D+   S+ ++W  P      ++  Y V   
Sbjct: 16321 GLSEPSPPSAYQKACDPIYKPGPPNNPKVIDITRSSVFLSWSKPIYDGGCEIQGYIVEKC 16380

Query: 1759  SPEDGIHELFPAPDGEEDT-AELQGLRPGSEYTVSVVAL-------HDDMESQPLIGTQS 1810
                 G   +   P G   T  E++ L    EY   + A+       H D+    ++  + 
Sbjct: 16381 DVSVGEWTMCTPPTGINKTNIEVEKLLEKHEYNFRICAINKAGVGEHADVPGPIIVEEKL 16440

Query: 1811  TAIPAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEK----TGPMKEINLAPDSS 1866
              A     DL+  ++                   + R TP+ K     G +++  +   +S
Sbjct: 16441 EAPDIDLDLELRKIINIRAGGSLR----LFVPIKGRPTPEVKWGKVDGEIRDAAIIDVTS 16496

Query: 1867  SVVVSGLMVATKYEVSVY--ALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITIS 1924
             S     L    +Y+   Y   L+++  ++ A   V  L+  SPP   +VT+ T+ +++I+
Sbjct: 16497 SFTSLVLDNVNRYDSGKYTLTLENSSGTKSAFVTVRVLDTPSPPVNLKVTEITKDSVSIT 16556

Query: 1925  WRTKT----ETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDN 1980
             W          I  + V+   A  ++           S+ I  LQ G  Y   +   N+ 
Sbjct: 16557 WEPPLLDGGSKIKNYIVEKREATRKSYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAENEY 16616

Query: 1981  ARSSPV----VIDASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPG 2032
                 P      I  +     P  +     T NS+ +SW  P     ++I  YI++ +   
Sbjct: 16617 GIGLPAQTADPIKVAEVPQPPGKITVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKH 16676

Query: 2033  SPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQKTPFVTHP 2092
             S       R +    +A IT L  G EY   V+A+    +S+P       V K   V  P
Sbjct: 16677 SEKWSECARVKS--LQAVITNLTQGEEYLFRVVAVNEKGRSDPRSLAVPIVAK-DLVIEP 16733

Query: 2093  GYDTGNGIQLPGTSGQQPSVGQQMIFEEHGFRRTTPPTTATPIRHRPRP 2141
                       P  S     VGQ +  E              PI  RP+P
Sbjct: 16734 DVK-------PAFSSYSVQVGQDLKIE-------------VPISGRPKP 16762



 Score = 78.2 bits (191), Expect = 9e-14
 Identities = 285/1428 (19%), Positives = 490/1428 (34%), Gaps = 237/1428 (16%)

Query: 690   QEVTRFDFTTTSTST---------------PVTSNTVTGET-------------TPFSPL 721
             ++  R +F TT+TST               P+T+  + GE               P  P+
Sbjct: 14610 KQTQRVNFETTATSTILNINECVRSDSGPYPLTARNIVGEVGDVITIQVHDIPGPPTGPI 14669

Query: 722   VATSESVTEITASSFVVSWVSASDT----VSGFRVEYELSEEGDEPQYLDLPSTA--TSV 775
                     E+++     SW    +     +S + VE     + D   +++L +T   T+ 
Sbjct: 14670 -----KFDEVSSDFVTFSWDPPENDGGVPISNYVVEMR---QTDSTTWVELATTVIRTTY 14721

Query: 776   NIPDLLPGRKYIVNV-----YQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVR 830
                 L  G +Y   V     Y +      + I++      P  P  P V  V   S+ + 
Sbjct: 14722 KATRLTTGLEYQFRVKAQNRYGVGPGITSACIVANYPFKVPGPPGTPQVTAVTKDSMTIS 14781

Query: 831   WSRPQA----PITGYRIVYSPSVEGSSTELNLPETANSVTL-------SDLQPGVQYNIT 879
             W  P +    PI GY       VE       L +T +   +       S L  G+ Y   
Sbjct: 14782 WHEPLSDGGSPILGYH------VERKERNGILWQTVSKALVPGNIFKSSGLTDGIAYEFR 14835

Query: 880   IYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESA----VT 935
             + A     +S P    +        D    P  L     T   VT+ W  PE      +T
Sbjct: 14836 VIAENMAGKSKPSKPSEPMLALDPIDPPGKPVPLNITRHT---VTLKWAKPEYTGGFKIT 14892

Query: 936   GYRVDVIPVNLPGEHGQRLPISR---NTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQ 992
              Y V+    +LP     +   S    N F  V+GL+    Y F+V A +      P +  
Sbjct: 14893 SYIVE--KRDLPNGRWLKANFSNILENEFT-VSGLTEDAAYEFRVIAKNAAGAISPPSEP 14949

Query: 993   QTT-----KLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPS 1047
                      ++AP     V   D+ +L            +RL   ++ R  P        
Sbjct: 14950 SDAITCRDDVEAPKIKVDVKFKDTVILKAGE-------AFRLEADVSGRPPPTMEWSKDG 15002

Query: 1048  VSKYPLRNLQ-PASEYTVSLVAIKGNQESPKATGVFTTLQPGSSI-------------PP 1093
                     L+   ++++ +LV  K +          T   PG                PP
Sbjct: 15003 KELEGTAKLEIKIADFSTNLVN-KDSTRRDSGAYTLTATNPGGFAKHIFNVKVLDRPGPP 15061

Query: 1094  YN----TEVTETTIVITW-TPAPRIGFKLGVRPSQGGEAPREVTSDSGSIV------VSG 1142
                   TEVT    V++W  P    G K+     Q  E  R   ++  S V      V+ 
Sbjct: 15062 EGPLAVTEVTSEKCVLSWFPPLDDGGAKIDHYIVQKRETSRLAWTNVASEVQVTKLKVTK 15121

Query: 1143  LTPGVEYVYTIQVLRD---GQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLT-----VS 1194
             L  G EY++ +  +     G+  ++  V   V P  PP       NP+   +T     V 
Sbjct: 15122 LLKGNEYIFRVMAVNKYGVGEPLESEPV-LAVNPYGPPDP---PKNPEVTTITKDSMVVC 15177

Query: 1195  WERSTTP---DITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVK 1251
             W    +    +I  Y +      GQ+     +    D        L+ G EY   +    
Sbjct: 15178 WGHPDSDGGSEIINYIVERRDKAGQRWIKCNKKTLTDLRY-KVSGLTEGHEYEFRIMAEN 15236

Query: 1252  DDKESVP--------ISDTIIPEVPQLTDLSFVDITDSSIGLRWT-PL--NSSTIIGYRI 1300
                 S P          DT+    P   +   +D + SSI + W  P+    S I GY +
Sbjct: 15237 AAGISAPSPTSPFYKACDTVFKPGPP-GNPRVLDTSRSSISIAWNKPIYDGGSEITGYMV 15295

Query: 1301  TVVAAGEGI-PIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAP-----TTLTQ 1354
              +    E    I           YT+TGL    +Y I +  + + G   P     T   +
Sbjct: 15296 EIALPEEDEWQIVTPPAGLKATSYTITGLTENQEYKIRIYAMNSEGLGEPALVPGTPKAE 15355

Query: 1355  QTAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNE------------EDV 1402
                +PP  +L       D  +V      +I     L  + P+K              E +
Sbjct: 15356 DRMLPPEIEL-----DADLRKVV-----TIRACCTLRLFVPIKGRPAPEVKWARDHGESL 15405

Query: 1403  AELSISPSDNAVVL----TNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTGIDFS 1458
              + SI  + +  +L     N     +Y+++V +     +S  +  R       P  +   
Sbjct: 15406 DKASIESTSSYTLLIVGNVNRFDSGKYILTVENS-SGSKSAFVNVRVLDTPGPPQDLKVK 15464

Query: 1459  DITANSFTVHWIAPRATITGYRIRHH--PEHFSGRPREDRVPHS--RNSITLTNLTPGTE 1514
             ++T  S T+ W  P     G +I+++   +  S R     V  +  + S  +  L  G  
Sbjct: 15465 EVTKTSVTLTWDPPLLD-GGSKIKNYIVEKRESTRKAYSTVATNCHKTSWKVDQLQEGCS 15523

Query: 1515  YVVSIVALNGREES-PLLIGQQSTVSD---VPRDLEVVAATPTSLLISWDAP----AVTV 1566
             Y   ++A N      P    +    S+    P  + ++  T  S+ +SW+ P       +
Sbjct: 15524 YYFRVLAENEYGIGLPAETAESVKASERPLPPGKITLMDVTRNSVSLSWEKPEHDGGSRI 15583

Query: 1567  RYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPIS 1626
               Y +     G +      TV  ++  ATI+GL  G +Y+  V A   +G S      + 
Sbjct: 15584 LGYIVEMQTKGSDKWATCATVKVTE--ATITGLIQGEEYSFRVSAQNEKGISDPRQLSVP 15641

Query: 1627  INYRTEIDKPS------QMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKT 1680
             +  +  +  P+         V   +D  + V ++   +P   +     P       +T  
Sbjct: 15642 VIAKDLVIPPAFKLLFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLK-----QTTR 15696

Query: 1681  AGPDQTE----MTIEGL--QPTVEYVVSVYAQNPSGESQPLVQTAVTNIDRPKG--LAFT 1732
                + TE    +TI+    +    YVV +   N +GE+   +   V +   P    +   
Sbjct: 15697 VNAESTENNSLLTIKDACREDVGHYVVKL--TNSAGEAIETLNVIVLDKPGPPTGPVKMD 15754

Query: 1733  DVDVDSIKIAWESPQ----GQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSE 1788
             +V  DSI ++W  P+      ++ Y V          ++  A      T +   L+ G E
Sbjct: 15755 EVTADSITLSWGPPKYDGGSSINNYIVEKRDTSTTTWQIVSATVART-TIKACRLKTGCE 15813

Query: 1789  YTVSVVALH-----DDMESQPLIGTQSTAIPAPTDLKFTQVTPT-SLSAQWTPP----NV 1838
             Y   + A +       + S+P +      +P P       ++   S+  QW  P      
Sbjct: 15814 YQFRIAAENRYGKSTYLNSEPTVAQYPFKVPGPPGTPVVTLSSRDSMEVQWNEPISDGGS 15873

Query: 1839  QLTGYRVRVTPKEKTGPM-KEINLAP-DSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQ 1896
             ++ GY +    KE+   +  ++N  P   +    +GL    +YE  V A       +P++
Sbjct: 15874 RVIGYHLE--RKERNSILWVKLNKTPIPQTKFKTTGLEEGVEYEFRVSAENIVGIGKPSK 15931

Query: 1897  --GVVTTLENVSPPRRARVTDATETTITISWRTKT----ETITGFQVD 1938
                     +   PP R      T  ++T+ W+  T      ITG+ V+
Sbjct: 15932 VSECYVARDPCDPPGRPEAIIVTRNSVTLQWKKPTYDGGSKITGYIVE 15979



 Score = 75.1 bits (183), Expect = 8e-13
 Identities = 286/1351 (21%), Positives = 472/1351 (34%), Gaps = 234/1351 (17%)

Query: 797   GEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQ----APITGYRIVYSPSVEGS 852
             G +++ +       P  P D  V ++   S  + W  P     + IT Y +         
Sbjct: 10799 GSKTVSVKVLVLDKPGPPRDLEVSEIRKDSCYLTWKEPLDDGGSVITNYVVERRDVASAQ 10858

Query: 853   STELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRD 912
              + L+      S     L  G QY   + A  +      V   +             P+D
Sbjct: 10859 WSPLSATSKKKSHFAKHLNEGNQYLFRVAAENQYGRGPFVETPKPIKALDPLHPPGPPKD 10918

Query: 913   LQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPVNLPGEHGQRLPISRNTFAE----V 964
             L  V+V   +V+++W  P+    S +TGY V+        E G +  I   T       V
Sbjct: 10919 LHHVDVDKTEVSLVWNKPDRDGGSPITGYLVEY------QEEGTQDWIKFKTVTNLECVV 10972

Query: 965   TGLSPGVTYYFKVFA---VSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPR 1021
             TGL  G TY F+V A   V  G     +  +   KL  P+    V   +  V+   T  R
Sbjct: 10973 TGLQQGKTYRFRVKAENIVGLGLPDTTIPIECQEKLVPPSVELDVKLIEGLVVKAGTTVR 11032

Query: 1022  --AQITGYRL-TVGLTRRGQPRQYNVGPSV------SKYPLRNL--QPASEYTVSLVAIK 1070
               A I G  + T   T  G   + +   +V      S   ++N   +   EY +++    
Sbjct: 11033 FPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEYQITV---- 11088

Query: 1071  GNQESPKATGVFTTLQ--PGSSIPPYNT-EVTETTIVITWTPAPRIGFKLGVRPSQGGEA 1127
              N    K   V  T+   PG    P N  +VT   + I+W P           P   G +
Sbjct: 11089 SNAAGSKTVAVHLTVLDVPGPPTGPINILDVTPEHMTISWQP-----------PKDDGGS 11137

Query: 1128  P--------REVTSDSGSIVVSG----------LTPGVEYVYTIQV---LRDGQERDA-P 1165
             P        ++   D+  +V SG          L  G EYV+ ++    +  G   D+ P
Sbjct: 11138 PVINYIVEKQDTRKDTWGVVSSGSSKTKLKIPHLQKGCEYVFRVRAENKIGVGPPLDSTP 11197

Query: 1166  IVNK-VVTPLSPPTNLHLEANPDTGVLTVSWERSTTPD---ITGY------------RIT 1209
              V K   +P SPP    +  +      TVSW    +     ITGY            R+ 
Sbjct: 11198 TVAKHKFSPPSPPGK-PVVTDITENAATVSWTLPKSDGGSPITGYYMERREVTGKWVRVN 11256

Query: 1210  TTP--------TNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISD 1261
              TP        T   +GN+ E  V A+       NL+   + + S   +K  +   PI  
Sbjct: 11257 KTPIADLKFRVTGLYEGNTYEFRVFAE-------NLAGLSKPSPSSDPIKACR---PIKP 11306

Query: 1262  TIIPEVPQLTDLSFVDITDSSIGLRWT-PLNS--STIIGYRITVVAAG--EGIPIFEDFV 1316
                P  P+L D S       +  L WT PL+   S I+GY +     G  +   I +D +
Sbjct: 11307 PGPPINPKLKDKS-----RETADLVWTKPLSDGGSPILGYVVECQKPGTAQWNRINKDEL 11361

Query: 1317  DSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAV-----PPPTDLRFTNIGP 1371
                  +  V GL  G +Y   +      GE  P  L +         PP  +L  T    
Sbjct: 11362 IRQCAF-RVPGLIEGNEYRFRIKAANIVGEGEPRELAESVIAKDILHPPEVELDVTCRDV 11420

Query: 1372  DTMRVTWA----------PPPSIDLTN---FLVRYSPVKNEEDV--AELSISPSDNAVVL 1416
              T+RV             P P I  T     LVR   V   +D+   EL I  +  A   
Sbjct: 11421 ITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREKRVDLIQDLPRVELQIKEAVRA--- 11477

Query: 1417  TNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSP---TGIDFSDITANSFTVHWIAPR 1473
                    +Y++S  +     + + +       LD P     +  +++T  + T+ W  P 
Sbjct: 11478 ----DHGKYIISAKNSSGHAQGSAI----VNVLDRPGPCQNLKVTNVTKENCTISWENPL 11529

Query: 1474  ----ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNG----- 1524
                 + IT + + +   +  G          R  +   NL    EY   + A N      
Sbjct: 11530 DNGGSEITNFIVEYRKPNQKGWSIVASDVTKR--LIKANLLANNEYYFRVCAENKVGVGP 11587

Query: 1525  --REESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYG---ETGGN 1579
                 ++P+L          P +L +     T + + W  P        ++Y       G+
Sbjct: 11588 TIETKTPILAINPIDRPGEPENLHIADKGKTFVYLKWRRPDYDGGSPNLSYHVERRLKGS 11647

Query: 1580  SPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASS--KPISINYRTEIDKPS 1637
                +       K T  +  +   V+  I  + V  + +   S   K   +  + ++ KP 
Sbjct: 11648 DDWERVHKGSIKETHYM--VDRCVENQIYEFRVQTKNEGGESDWVKTEEVVVKEDLQKP- 11704

Query: 1638  QMQVTDVQDNSIS-VKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMT------I 1690
                   V D  +S V  + +   +   R+    +  P P    T   D T++T      I
Sbjct: 11705 ------VLDLKLSGVLTVKAGDTI---RLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKI 11755

Query: 1691  EGLQPTVEYVVSVYAQNPSGE--------SQPLVQTAVTNI-DRP---KGLAFTDVDVDS 1738
             +    + ++ ++   ++  G+        +   V  A  N+ D+P   + L   DV  D 
Sbjct: 11756 DTRADSSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATVNVLDKPGPVRNLKIVDVSSDR 11815

Query: 1739  IKIAWESPQG----QVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSV- 1793
               + W+ P+     ++  Y +     +  +   + A      T   + L  G+EY   V 
Sbjct: 11816 CTVCWDPPEDDGGCEIQNYILEKCETKRMVWSTYSATVLTPGTTVTR-LIEGNEYIFRVR 11874

Query: 1794  ----VALHDDMESQPLIGTQSTAIPA-PTDLKFTQVTPTSLSAQWTPPNVQ----LTGYR 1844
                 +      ES+P+I       P  P   + T+V+   ++  W PP       +TGY 
Sbjct: 11875 AENKIGTGPPTESKPVIAKTKYDKPGRPDPPEVTKVSKEEMTVVWNPPEYDGGKSITGYF 11934

Query: 1845  VRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKD------TLTSRPAQGV 1898
             +    K  T  +     A     + V  L+   +Y+  V A  +      +L SRP    
Sbjct: 11935 LEKKEKHSTRWVPVNKSAIPERRMKVQNLLPDHEYQFRVKAENEIGIGEPSLPSRPVVAK 11994

Query: 1899  VTTLENVSPPRRARVTDATETTITISWRTKT----ETITGFQV-------DAVPANGQTP 1947
                +E   PP   RV D T+ +IT+ W          I G+ V       DA P  G   
Sbjct: 11995 -DPIEPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAPIIGYVVEMRPKIADASPDEGWKR 12053

Query: 1948  IQRTIKPDVRSYTITGLQPGTDYKIYLYTLN 1978
                  +   + +T+T L    +Y+  +   N
Sbjct: 12054 CNAAAQLVRKEFTVTSLDENQEYEFRVCAQN 12084



 Score = 74.3 bits (181), Expect = 1e-12
 Identities = 276/1411 (19%), Positives = 484/1411 (34%), Gaps = 227/1411 (16%)

Query: 814   PPDPTVD--QVDDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTL 867
             PP P  D   +D  +  + W  P     + IT Y +       G         T  S  +
Sbjct: 12497 PPQPPFDISDIDADACSLSWHIPLEDGGSNITNYIVEKCDVSRGDWVTALASVTKTSCRV 12556

Query: 868   SDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPS-PRDLQFVEVTDVKVTIM 926
               L PG +Y   + A      S P+   +     P    VPS P++ +  +V    + + 
Sbjct: 12557 GKLIPGQEYIFRVRAENRFGISEPLTSPKMVAQFPFG--VPSEPKNARVTKVNKDCIFVA 12614

Query: 927   WTPPES----AVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSH 982
             W  P+S     + GY ++    N          + R+T     GL  G+ Y F+++A++ 
Sbjct: 12615 WDRPDSDGGSPIIGYLIERKERNSLLWVKANDTLVRSTEYPCAGLVEGLEYSFRIYALNK 12674

Query: 983   GRESKPL--TAQQTTKL--DAPTNLQFVNETDSTVLVRWTPPR----AQITGYRLTVGLT 1034
                S P   T   T ++  D P   + ++ T STV + W  P+    ++I GY +     
Sbjct: 12675 AGSSPPSKPTEYVTARMPVDPPGKPEVIDVTKSTVSLIWARPKHDGGSKIIGYFVEACKL 12734

Query: 1035  RRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPY 1094
                +  + N  P        +  P  EYT + +  K   +          + P S     
Sbjct: 12735 PGDKWVRCNTAP--------HQIPQEEYTATGLEEKAQYQFRAIARTAVNISPPS----- 12781

Query: 1095  NTEVTETTIVITWTPAPRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQ 1154
               E ++   ++     PRI   + ++     +A   V  D+   V     P V +     
Sbjct: 12782 --EPSDPVTILAENVPPRIDLSVAMKSLLTVKAGTNVCLDA--TVFGKPMPTVSWKKDGT 12837

Query: 1155  VLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTN 1214
             +L+  +     +   + T       L      D+G  T++ E S+       ++      
Sbjct: 12838 LLKPAEGIKMAMQRNLCT-----LELFSVNRKDSGDYTITAENSSGSKSATIKLKVLDKP 12892

Query: 1215  GQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYT--VKDDKESVPISDTIIPEVPQLTD 1272
             G   +     +++D++  +++   P LE   S  T  + D +E      T  P   Q++ 
Sbjct: 12893 GPPASVKINKMYSDRAMLSWE---PPLEDGGSEITNYIVDKRE------TSRPNWAQVS- 12942

Query: 1273  LSFVDITDSSIGLRWTPLNSSTIIG--YRITVVAA---GEGIPIFEDFVDSSVGYYTVTG 1327
              + V IT  S+           I G  Y+  + A    G G P+F               
Sbjct: 12943 -ATVPITSCSV--------EKLIEGHEYQFRICAENKYGVGDPVFT-------------- 12979

Query: 1328  LEPGIDYDISVITLINGGESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAPPPS---I 1384
              EP I               A           PP     +NI  D M V+W PP      
Sbjct: 12980 -EPAI---------------AKNPYDPPGRCDPPV---ISNITKDHMTVSWKPPADDGGS 13020

Query: 1385  DLTNFLV--RYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLR 1442
              +T +L+  R +   N   V    I   +  +  T L  GTEY   V+++ +     P  
Sbjct: 13021 PITGYLLEKRETQAVNWTKVNRKPII--ERTLKATGLQEGTEYEFRVTAINKAGPGKPSD 13078

Query: 1443  GRQKTGLDSP-------TGIDFSDITANSFTVHWIAPR----ATITGYRIRHHPEHFSGR 1491
               +      P             D T +S ++ W  P     + I GY +          
Sbjct: 13079 ASKAAYARDPQYPPGPPAFPKVYDTTRSSVSLSWGKPAYDGGSPIIGYLVEVKRADSDNW 13138

Query: 1492  PREDRVPH-SRNSITLTNLTPGTEYVVSIVALNGREES-PLLIGQQSTVSDV--PRDLEV 1547
              R +   +  +    +T L   T+Y   + A+N    S P  +  +    D+  P + E+
Sbjct: 13139 VRCNLPQNLQKTRFEVTGLMEDTQYQFRVYAVNKIGYSDPSDVPDKHYPKDILIPPEGEL 13198

Query: 1548  VAATPTSLLISWDAPAVTVRYY---------RITYGETGGNSPVQEFTVPGSKSTATISG 1598
              A    +L++      VT+R Y         +IT+ +   N   +      S    T   
Sbjct: 13199 DADLRKTLILR---AGVTMRLYVPVKGRPPPKITWSKPNVNLRDRIGLDIKSTDFDTFLR 13255

Query: 1599  LKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLP--- 1655
              +    Y    Y +T           I +        P  + V ++  +S  V W P   
Sbjct: 13256 CENVNKYDAGKYILTLENSCGKKEYTIVVKVLDTPGPPVNVTVKEISKDSAYVTWEPPII 13315

Query: 1656  -SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQP 1714
                SP+  Y V            T T    +T   +  L+    Y   V+A+N  G   P
Sbjct: 13316 DGGSPIINYVVQKRDAERKS-WSTVTTECSKTSFRVANLEEGKSYFFRVFAENEYGIGDP 13374

Query: 1715  LVQTAVTNIDRPKG----LAFTDVDVDSIKIAWESPQG----QVSRYRVTYSSPEDGIHE 1766
                       +  G    L    V   S  I W+ P      ++  Y V + + E+    
Sbjct: 13375 GETRDAVKASQTPGPVVDLKVRSVSKSSCSIGWKKPHSDGGSRIIGYVVDFLTEENKWQR 13434

Query: 1767  LFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTP 1826
             +  +   +    +L     G EYT  V A +++ E  P        + A  D     V  
Sbjct: 13435 VMKSLSLQYSAKDLT---EGKEYTFRVSAENENGEGTP----SEITVVARDD-----VVA 13482

Query: 1827  TSLSAQWTPPNVQL----TGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVS 1882
               L  +  P    L    + +R+++  K K  P        D        L   T+  V 
Sbjct: 13483 PDLDLKGLPDLCYLAKENSNFRLKIPIKGKPAPSVSWKKGEDP-------LATDTRVSVE 13535

Query: 1883  VYALKDTLTSRPAQ----GVVT-TLENVSPPRRARVT-----------------DATETT 1920
               A+  TL     Q    G  T TL+NV+  +   ++                 + T   
Sbjct: 13536 SSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKEGTISIKVVGKPGIPTGPIKFDEVTAEA 13595

Query: 1921  ITISWRTKTET----ITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYL-- 1974
             +T+ W    +     IT + ++   +     +         ++ +T L  G +Y   +  
Sbjct: 13596 MTLKWAPPKDDGGSEITNYILEKRDSVNNKWVTCASAVQKTTFRVTRLHEGMEYTFRVSA 13655

Query: 1975  ---YTLNDNARSSPVVIDASTAI-DAPSNLRFLATTPNSLLVSWQPPR----ARITGYII 2026
                Y + +  +S P+V      + DAP     +    +S+ ++W  P+    + ITGY +
Sbjct: 13656 ENKYGVGEGLKSEPIVARHPFDVPDAPPPPNIVDVRHDSVSLTWTDPKKTGGSPITGYHL 13715

Query: 2027  KYEKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIAL------KNNQKSEPLI--- 2077
             ++++  S   +   +    + +  +TGL  G EY   V+A+      K +  SEP++   
Sbjct: 13716 EFKERNSLLWKRANKTPIRMRDFKVTGLTEGLEYEFRVMAINLAGVGKPSLPSEPVVALD 13775

Query: 2078  -----GRKKTV-----QKTPFVTHPGYDTGN 2098
                  G+ + +       T   T P YD G+
Sbjct: 13776 PIDPPGKPEVINITRNSVTLIWTEPKYDGGH 13806



 Score = 72.8 bits (177), Expect = 4e-12
 Identities = 334/1588 (21%), Positives = 550/1588 (34%), Gaps = 285/1588 (17%)

Query: 828   VVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAV 883
             ++ WS P+    + ITG+ I+     +  +    +    +   ++ L  G +Y   + A 
Sbjct: 8717  LLNWSDPEDDGGSEITGF-IIERKDAKMHTWRQPIETERSKCDITGLLEGQEYKFRVIAK 8775

Query: 884   EENQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPES----AVTGYRV 939
              +     PV I       P      SP  L + E T   +T+ W  P S     + GY +
Sbjct: 8776  NKFGCGPPVEIGPILAVDPLGPPT-SPERLTYTERTKSTITLDWKEPRSNGGSPIQGYII 8834

Query: 940   DVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLD- 998
             +    + P        +   T   V  L     Y F+V AV+   ES+P         D 
Sbjct: 8835  EKRRHDKPDFERVNKRLCPTTSFLVENLDEHQMYEFRVKAVNEIGESEPSLPLNVVIQDD 8894

Query: 999   --APTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPR-QYNVGPSVSKYPLRN 1055
                PT    ++    T+ V+   P        +   +T    P+ +++   +V + P   
Sbjct: 8895  EVPPTIKLRLSVRGDTIKVKAGEP------VHIPADVTGLPMPKIEWSKNETVIEKPTDA 8948

Query: 1056  LQPASEYTVSLVAIKGNQESPKAT----GVFTTLQP---GSSI------------PPYNT 1096
             LQ   E  VS    K     PKA     G +T       GS              PP N 
Sbjct: 8949  LQITKE-EVSRSEAKTELSIPKAVREDKGTYTVTASNRLGSVFRNVHVEVYDRPSPPRNL 9007

Query: 1097  EVTET---TIVITW-TPAPRIGFKLGVRPSQGGEAPR------EVTSDSGS--IVVSGLT 1144
              VT+    +  +TW  P    G ++        +A R      EVT+ +      +  L 
Sbjct: 9008  AVTDIKAESCYLTWDAPLDNGGSEITHYVIDKRDASRKKAEWEEVTNTAVEKRYGIWKLI 9067

Query: 1145  PGVEYVYTIQVLR-----DGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSW---- 1195
             P  +Y + ++ +      D  + D  ++        PP    + A    G + VSW    
Sbjct: 9068  PNGQYEFRVRAVNKYGISDECKSDKVVIQDPYRLPGPPGKPKVLARTK-GSMLVSWTPPL 9126

Query: 1196  ERSTTPDITGYRITTTPTNGQQGNSLEE--VVHADQSSCTFD--NLSPGLEYNVSVYTVK 1251
             +   +P ITGY +          + +    +         F+   L  G++Y      + 
Sbjct: 9127  DNGGSP-ITGYWLEKREEGSPYWSRVSRAPITKVGLKGVEFNVPRLLEGVKYQFRAMAIN 9185

Query: 1252  --------DDKESVPISDTIIPEVPQLTDLSFVDITDSSIGLRWTPL---NSSTIIGYRI 1300
                     +  +     D I P  P        D T SSI L W P      S I GY +
Sbjct: 9186  AAGIGPPSEPSDPEVAGDPIFPPGPPSCP-EVKDKTKSSISLGWKPPAKDGGSPIKGYIV 9244

Query: 1301  TVVAAG--EGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAV 1358
              +   G  +   + E     +     V  L+    Y   V  +   GES P+  T +   
Sbjct: 9245  EMQEEGTTDWKRVNEPDKLITTCECVVPNLKELRKYRFRVKAVNEAGESEPSDTTGEI-- 9302

Query: 1359  PPPTDLR-----FTNIGPDTMRVTWA-------------PPPS----IDLTNFLVRYSPV 1396
              P TD++     F +IG     V  A             P P      D          V
Sbjct: 9303  -PATDIQEEPEVFIDIGAQDCLVCKAGSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGV 9361

Query: 1397  KNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTP-LRGRQKTGLDSPTGI 1455
              +  + A+L  + + + +++           S+++  +  + T   R +       P  +
Sbjct: 9362  HDIPEDAQLETAENSSVIIIPECKRSHTGKYSITAKNKAGQKTANCRVKVMDVPGPPKDL 9421

Query: 1456  DFSDITANSFTVHWIAPRAT----ITGYRIRHHPEHFSGRPREDRVPH-SRNSITLTNLT 1510
               SDIT  S  + W  P       I GY I        G+      P     +  + +L 
Sbjct: 9422  KVSDITRGSCRLSWKMPDDDGGDRIKGYVIEKRT--IDGKAWTKVNPDCGSTTFVVPDLL 9479

Query: 1511  PGTEYVVSIVALNGREESPLLIGQQSTVS-------DVPRDLEVVAATPTSLLISWDAPA 1563
                +Y   + A N     P +   Q T +       D P  L++   T  ++ +SW  P 
Sbjct: 9480  SEQQYFFRVRAENRFGIGPPVETIQRTTARDPIYPPDPPIKLKIGLITKNTVHLSWKPP- 9538

Query: 1564  VTVRYYRITYGETGGNSPVQEFTVP-------GSKSTA--------------TISGLKPG 1602
                        +  G SPV  + V        G+K  A              T+  L  G
Sbjct: 9539  -----------KNDGGSPVTHYIVECLAWDPTGTKKEAWRQCNKRDVEELQFTVEDLVEG 9587

Query: 1603  VDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTG 1662
              +Y   V AV   G S  S+             P   Q  D+   SI +K        T 
Sbjct: 9588  GEYEFRVKAVNAAGVSKPSATV----------GPCDCQRPDMPP-SIDLKEFMEVEEGTN 9636

Query: 1663  YRVTTTPKNGPGPT----KTKTAGPDQTEMTIEGLQPTVEYV----VSVYAQNPSGESQP 1714
               +    K  P PT    K     PD  E  +         V      V  Q+   ++  
Sbjct: 9637  VNIVAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDTGL 9696

Query: 1715  LVQTAVTNIDR---------------PKG-LAFTDVDVDSIKIAWESPQ----GQVSRYR 1754
                TAV N+                 P G + F  V  D + ++W  P+     +++ Y 
Sbjct: 9697  YTITAVNNLGTASKEMRLNVLGRPGPPVGPIKFESVSADQMTLSWFPPKDDGGSKITNYV 9756

Query: 1755  VTY--SSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVA-----LHDDMESQPLIG 1807
             +    ++ +  +H    + + +E T  +  L  G EY   ++A     + + ++S+P   
Sbjct: 9757  IEKREANRKTWVHV---SSEPKECTYTIPKLLEGHEYVFRIMAQNKYGIGEPLDSEPETA 9813

Query: 1808  TQSTAIP-APTDLKFTQVTPTSLSAQWTPPNVQ----LTGYRVRVTPKEKTGPM-KEINL 1861
                 ++P AP     + VT  S++  W  P       +TGY + +  K+ T    K +N 
Sbjct: 9814  RNLFSVPGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPVTGYWLEM--KDTTSKRWKRVNR 9871

Query: 1862  APDSS-----SVVVSGLMVATKYEVSVYALKD------TLTSRPAQGVVTTLENVSPPRR 1910
              P  +     S  V+GL+  + Y+  VYA+        +L S PA    T  + ++PP  
Sbjct: 9872  DPIKAMTLGVSYKVTGLIEGSDYQFRVYAINAAGVGPASLPSDPA----TARDPIAPPGP 9927

Query: 1911  A--RVTDATETTITISWRTKTET----ITGFQVDAVPANGQTPIQRTIKPDVRS--YTIT 1962
                +VTD T+++  + W    +     +TG+ V+     G+   ++    +VR     +T
Sbjct: 9928  PFPKVTDWTKSSADLEWSPPLKDGGSKVTGYIVE-YKEEGKEEWEKGKDKEVRGTKLVVT 9986

Query: 1963  GLQPGTDYKIYLYTLNDNARSSPV----VIDASTAIDAPSNLRFLATTPNSLLVSWQPPR 2018
             GL+ G  YK  +  +N      P     VI+    + +P +L+  A+  + ++V      
Sbjct: 9987  GLKEGAFYKFRVRAVNIAGIGEPGEVTDVIEMKDRLVSP-DLQLDASVRDRIVVH-AGGV 10044

Query: 2019  ARITGYIIKYEKPGSPPREVV--PRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPL 2076
              RI  Y+      G PP  V      R    EATI      T      + +KN Q+S   
Sbjct: 10045 IRIIAYV-----SGKPPPTVTWNMNERTLPQEATIE-----TTAISSSMVIKNCQRSHQG 10094

Query: 2077  I----------GRKKTV----------QKTPFVTHPGYDTGNGIQL----PGTSGQQPSV 2112
             +           RKKT+            TPF+ H    T    +L    P   G  P +
Sbjct: 10095 VYSLLAKNEAGERKKTIIVDVLDVPGPVGTPFLAHNL--TNESCKLTWFSPEDDGGSP-I 10151

Query: 2113  GQQMIFEEHGFRRTTPPTTATPIRHRPRPYPPNVGQ----EALSQTTISWAPFQDTSEYI 2168
                +I +    RR   P T T  R          G+       ++ +I   PF +TSE +
Sbjct: 10152 TNYVIEKRESDRRAWTPVTYTVTRQNATVQGLIQGKAYFFRIAAENSIGMGPFVETSEAL 10211

Query: 2169  ISCHPVGTDEEPLQFRVPG-TSTSATLT 2195
             +   P+   E P    V   T  + TLT
Sbjct: 10212 VIREPITVPERPEDLEVKEVTKNTVTLT 10239



 Score = 72.0 bits (175), Expect = 7e-12
 Identities = 342/1612 (21%), Positives = 545/1612 (33%), Gaps = 290/1612 (17%)

Query: 628   IQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISI 684
             + W +P+    S I+ Y++  R  +    W   T      + T++GL  G  Y  ++ + 
Sbjct: 10138 LTWFSPEDDGGSPITNYVIEKRESDRRA-WTPVTYTVTRQNATVQGLIQGKAYFFRIAAE 10196

Query: 685   QQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSAS 744
                G        F  TS +  +        T P  P       V E+T ++  ++W    
Sbjct: 10197 NSIGMGP-----FVETSEALVIREPI----TVPERP---EDLEVKEVTKNTVTLTWNPPK 10244

Query: 745   DTVSGFRVEYELSEE--GDEPQYLDLPSTATS--VNIPDLLPGRKYIVNVYQISEDGEQS 800
                    + Y L     G E  +        S    +  L  G  Y   V  ++  G+  
Sbjct: 10245 YDGGSEIINYVLESRLIGTEKFHKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGK 10304

Query: 801   LILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPE 860
                 T   T  D    PT+       + +R     A    Y     P V     E ++ E
Sbjct: 10305 PSFCTKPITCKDELAPPTLHLDFRDKLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLE 10364

Query: 861   TANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQET---TGTPRSDTVPSPRD----L 913
               +  T     P       I A   +     VV++  T    G  + + V  P      +
Sbjct: 10365 --DDRTHIKTTPATLALEKIKAKRSDSGKYCVVVENSTGSRKGFCQVNVVDRPGPPVGPV 10422

Query: 914   QFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPGEHGQRLPI---SRNTFAEVTG 966
              F EVT   + I W PP     S +T Y ++   V         +P+   S  T  +V+ 
Sbjct: 10423 SFDEVTKDYMVISWKPPLDDGGSKITNYIIEKKEVG----KDVWMPVTSASAKTTCKVSK 10478

Query: 967   LSPGVTYYFKVFAVSHGRESKPLTAQQTTKLD------APTNLQFVNETDSTVLVRWTPP 1020
             L  G  Y F++ A +    S PL +      D      AP        T  + LV W  P
Sbjct: 10479 LLEGKDYIFRIHAENLYGISDPLVSDSMKAKDRFRVPDAPDQPIVTEVTKDSALVTWNKP 10538

Query: 1021  R---AQITGYRLTVGLTRRGQPRQYNVGP--SVSKYPLRNLQPASEYTVSLVA---IKGN 1072
                   IT Y L    T   +  +    P    +K+ + +L    +Y   + A   I   
Sbjct: 10539 HDGGKPITNYILEKRETMSKRWARVTKDPIHPYTKFRVPDLLEGCQYEFRVSAENEIGIG 10598

Query: 1073  QESPKATGVFTTLQPGSSIPPYNTEVTETT---IVITWTPAPRIGFKLGVRPSQGGEAPR 1129
               SP +  VF         PP N E  +TT   + +TW P                  PR
Sbjct: 10599 DPSPPSKPVFAKDPIAKPSPPVNPEAIDTTCNSVDLTWQP------------------PR 10640

Query: 1130  EVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTG 1189
                 D GS ++        Y+   Q + D + R A              N   E+ P+T 
Sbjct: 10641 H---DGGSKILG-------YIVEYQKVGDEEWRRA--------------NHTPESCPETK 10676

Query: 1190  VLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPG---LEYNVS 1246
                       T     +R+      G+      +  H  +     D L P    L+ N++
Sbjct: 10677 YKVTGLRDGQTYK---FRVLAVNAAGES-----DPAHVPEPVLVKDRLEPPELILDANMA 10728

Query: 1247  VYTVKDDKESVPISDT-----IIPEVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGYRIT 1301
                    ++ + + DT     II  VP      F  +T       W   +       RI 
Sbjct: 10729 ------REQHIKVGDTLRLSAIIKGVP------FPKVT-------WKKEDRDAPTKARID 10769

Query: 1302  VVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAVPPP 1361
             V   G  + I  +      G Y++T   P     +SV  L+                 PP
Sbjct: 10770 VTPVGSKLEI-RNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDKPG------------PP 10816

Query: 1362  TDLRFTNIGPDTMRVTWAPPPSID---LTNFLVRYSPVKNEEDVAELSISPSDNAVVLTN 1418
              DL  + I  D+  +TW  P       +TN++V    V + +  + LS +    +    +
Sbjct: 10817 RDLEVSEIRKDSCYLTWKEPLDDGGSVITNYVVERRDVASAQ-WSPLSATSKKKSHFAKH 10875

Query: 1419  LLPGTEYVVSVSSVYEQHESTPLRGRQKT--GLDS------PTGIDFSDITANSFTVHWI 1470
             L  G +Y+  V++   Q+   P     K    LD       P  +   D+     ++ W 
Sbjct: 10876 LNEGNQYLFRVAAE-NQYGRGPFVETPKPIKALDPLHPPGPPKDLHHVDVDKTEVSLVWN 10934

Query: 1471  APR----ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN--- 1523
              P     + ITGY + +  E      +   V +      +T L  G  Y   + A N   
Sbjct: 10935 KPDRDGGSPITGYLVEYQEEGTQDWIKFKTVTNLE--CVVTGLQQGKTYRFRVKAENIVG 10992

Query: 1524  -GREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPV 1582
              G  ++ + I  Q  +  VP  +E+       L++       TVR+  I  G      P 
Sbjct: 10993 LGLPDTTIPIECQEKL--VPPSVELDVKLIEGLVVK---AGTTVRFPAIIRGVP---VPT 11044

Query: 1583  QEFTVPGSK---------------STATISGL--KPGVDYTITVYAVTGRGDSPASSKPI 1625
              ++T  GS+               S  TI     +   +Y ITV        + A SK +
Sbjct: 11045 AKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEYQITV-------SNAAGSKTV 11097

Query: 1626  SINYRTEIDKPSQ----MQVTDVQDNSISVKWLP----SSSPVTGYRVTT--TPKNGPGP 1675
             +++  T +D P      + + DV    +++ W P      SPV  Y V    T K+  G 
Sbjct: 11098 AVHL-TVLDVPGPPTGPINILDVTPEHMTISWQPPKDDGGSPVINYIVEKQDTRKDTWGV 11156

Query: 1676  TKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDR------PKGL 1729
                 ++G  +T++ I  LQ   EYV  V A+N  G   PL  T      +      P   
Sbjct: 11157 V---SSGSSKTKLKIPHLQKGCEYVFRVRAENKIGVGPPLDSTPTVAKHKFSPPSPPGKP 11213

Query: 1730  AFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQ----GLRP 1785
               TD+  ++  ++W  P+         Y      +   +   + +   A+L+    GL  
Sbjct: 11214 VVTDITENAATVSWTLPKSDGGSPITGYYMERREVTGKWVRVN-KTPIADLKFRVTGLYE 11272

Query: 1786  GSEYTVSVVALH------DDMESQPLIGTQSTAIPA-PTDLKFTQVTPTSLSAQWTPP-- 1836
             G+ Y   V A +          S P+   +    P  P + K    +  +    WT P  
Sbjct: 11273 GNTYEFRVFAENLAGLSKPSPSSDPIKACRPIKPPGPPINPKLKDKSRETADLVWTKPLS 11332

Query: 1837  --NVQLTGYRVRVTPKEKTGPMKEINLAP--DSSSVVVSGLMVATKYEVSVYALKDTLTS 1892
                  + GY V    K  T     IN        +  V GL+   +Y   + A       
Sbjct: 11333 DGGSPILGYVVE-CQKPGTAQWNRINKDELIRQCAFRVPGLIEGNEYRFRIKAANIVGEG 11391

Query: 1893  RP---AQGVVTTLENVSPPR-------RARVTDATETTITISWRTK-------TETITG- 1934
              P   A+ V+   + + PP        R  +T     TI I  R K       T T  G 
Sbjct: 11392 EPRELAESVIAK-DILHPPEVELDVTCRDVITVRVGQTIRILARVKGRPEPDITWTKEGK 11450

Query: 1935  -----FQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVID 1989
                   +VD +    +  +Q  IK  VR+           Y I     + +A+ S +V  
Sbjct: 11451 VLVREKRVDLIQDLPRVELQ--IKEAVRA-------DHGKYIISAKNSSGHAQGSAIV-- 11499

Query: 1990  ASTAIDAP---SNLRFLATTPNSLLVSWQPP----RARITGYIIKYEKPGSPPREVVPRP 2042
                 +D P    NL+    T  +  +SW+ P     + IT +I++Y KP      +V   
Sbjct: 11500 --NVLDRPGPCQNLKVTNVTKENCTISWENPLDNGGSEITNFIVEYRKPNQKGWSIV--- 11554

Query: 2043  RPGVTEATI-TGLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQKTPFVTHPG 2093
                VT+  I   L    EY   V A +N     P I  K  +     +  PG
Sbjct: 11555 ASDVTKRLIKANLLANNEYYFRVCA-ENKVGVGPTIETKTPILAINPIDRPG 11605



 Score = 64.3 bits (155), Expect = 1e-09
 Identities = 115/519 (22%), Positives = 183/519 (35%), Gaps = 81/519 (15%)

Query: 1633  IDKPS---QMQVTDVQDNSISVKWLPSSSP----VTGYRVTTTP-KNGPGPTKTKTAGPD 1684
             +DKP     +++ DV  +  +V W P        +  Y +     K     T + T    
Sbjct: 11797 LDKPGPVRNLKIVDVSSDRCTVCWDPPEDDGGCEIQNYILEKCETKRMVWSTYSATVLTP 11856

Query: 1685  QTEMT--IEGLQPTVEYVVSVYAQN-----PSGESQPLV-QTAVTNIDRPKGLAFTDVDV 1736
              T +T  IEG     EY+  V A+N     P  ES+P++ +T      RP     T V  
Sbjct: 11857 GTTVTRLIEGN----EYIFRVRAENKIGTGPPTESKPVIAKTKYDKPGRPDPPEVTKVSK 11912

Query: 1737  DSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGE----EDTAELQGLRPGSEYTVS 1792
             + + + W  P+    +    Y   +   H     P  +    E   ++Q L P  EY   
Sbjct: 11913 EEMTVVWNPPEYDGGKSITGYFLEKKEKHSTRWVPVNKSAIPERRMKVQNLLPDHEYQFR 11972

Query: 1793  VVALHD------DMESQPLIGTQSTAIPAP-TDLKFTQVTPTSLSAQWTPP----NVQLT 1841
             V A ++       + S+P++       P P T+ +    T  S++  W  P       + 
Sbjct: 11973 VKAENEIGIGEPSLPSRPVVAKDPIEPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAPII 12032

Query: 1842  GYRVRVTPKEKTGP----MKEINLAPD--SSSVVVSGLMVATKYEVSVYALKDTLTSRPA 1895
             GY V + PK          K  N A         V+ L    +YE  V A       RPA
Sbjct: 12033 GYVVEMRPKIADASPDEGWKRCNAAAQLVRKEFTVTSLDENQEYEFRVCAQNQVGIGRPA 12092

Query: 1896  Q--GVVTTLENVSPPRRARVTDATETTIT-------------------ISWRTK--TETI 1932
             +    +   E + PP         +  I                    ++WR       +
Sbjct: 12093 ELKEAIKPKEILEPPEIDLDASMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVV 12152

Query: 1933  TGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDAST 1992
                QVD V       I  + + D   Y++T + P  +  +++     N R    V+D   
Sbjct: 12153 RKGQVDLVDTMAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFV-----NVR----VLDTPG 12203

Query: 1993  AIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREVVPRPRPGVTE 2048
              +   S+L+    T  S  VSW PP     +++T YI++  +        V  P    T 
Sbjct: 12204 PV---SDLKVSDVTKTSCHVSWAPPENDGGSQVTHYIVEKREADRKTWSTVT-PEVKKTS 12259

Query: 2049  ATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQKTP 2087
               +T L PG EY   V A+       P    K  +   P
Sbjct: 12260 FHVTNLVPGNEYYFRVTAVNEYGPGVPTDVPKPVLASDP 12298



 Score = 61.6 bits (148), Expect = 9e-09
 Identities = 181/841 (21%), Positives = 296/841 (35%), Gaps = 156/841 (18%)

Query: 1360 PPTDLRFTNIGPDTMRVTWAPPPS---IDLTNFLVRYSPVKNEEDVAELSISPSDNAVVL 1416
            P  +L  T      + + W  P +     +  ++V    +K +  V     + S    V 
Sbjct: 6595 PVRNLEVTETFDGEVSLAWEEPLTDGGSKIIGYVVERRDIKRKTWVLATDRAESCEFTVT 6654

Query: 1417 TNLLPGTEYVVSVSS-----VYEQHES-TPLRGRQKTGLDSPT-GIDFSDITANSFTVHW 1469
                 G EY+  VS+       E  E+  P+  R K  +  P   +  +D+     ++ W
Sbjct: 6655 GLQKGGVEYLFRVSARNRVGTGEPVETDNPVEARSKYDVPGPPLNVTITDVNRFGVSLTW 6714

Query: 1470 IAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGR 1525
              P     A IT Y I    +          V     S T+T++  G EY   +     R
Sbjct: 6715 EPPEYDGGAEITNYVIELRDKTSIRWDTAMTVRAEDLSATVTDVVEGQEYSFRV-----R 6769

Query: 1526 EESPLLIGQQSTVSDV------------PRDLEVVAATPTSLLISWDAP----AVTVRYY 1569
             ++ + +G+ S  +              P +L     T +S+ + W+ P       +  Y
Sbjct: 6770 AQNRIGVGKPSAATPFVKVADPIERPSPPVNLTSSDQTQSSVQLKWEPPLKDGGSPILGY 6829

Query: 1570 RITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINY 1629
             I   E G ++ ++       + T  ++GL+ G  Y   V A    G S  S     +  
Sbjct: 6830 IIERCEEGKDNWIRCNMKLVPELTYKVTGLEKGNKYLYRVSAENKAGVSDPSEILGPLTA 6889

Query: 1630 RTEIDKPSQMQVTDVQDNSISVKWLPSSS--PVTGYRVTTTPKNGPGPTKTKTAGPDQTE 1687
                 +P+ M ++  +D    +   P +   P TGY         P PT T   G    E
Sbjct: 6890 DDAFVEPT-MDLSAFKDGLEVIVPNPITILVPSTGY---------PRPTATWCFGDKVLE 6939

Query: 1688 ----MTIEGLQPTVEYVVSVYAQNPSG----ESQPLVQTAVTNID--------RPKGLAF 1731
                + ++ L    E V+S   ++  G    + +  V+T    ID         PK L F
Sbjct: 6940 TGDRVKMKTLSAYAELVISPSERSDKGIYTLKLENRVKTISGEIDVNVIARPSAPKELKF 6999

Query: 1732 TDVDVDSIKIAWESPQ----GQVSRY--------RVTYSSPEDGIHEL-FPAPDGEEDTA 1778
             D+  DS+ + WE P       ++ Y        R T++   D + +L F  PD      
Sbjct: 7000 GDITKDSVHLTWEPPDDDGGSPLTGYVVEKREVSRKTWTKVMDFVTDLEFTVPD------ 7053

Query: 1779 ELQGLRPGSEYTVSVVALHDDMESQPL-------IGTQSTAIPAPTDLKFTQVTPTSLSA 1831
                L  G EY   V A +     +P        + T +T    P ++K+   T  S+  
Sbjct: 7054 ----LVQGKEYLFKVCARNKCGPGEPAYVDEPVNMSTPATVPDPPENVKWRDRTANSIFL 7109

Query: 1832 QWTPP----NVQLTGYRVRVTPKEKTGPMKEINLAPD--SSSVVVSGLMVATKYEVSVYA 1885
             W PP      ++ GY V   P+   G  K +        + + V+GL     Y   V A
Sbjct: 7110 TWDPPKNDGGSRIKGYIVERCPR---GSDKWVACGEPVAETKMEVTGLEEGKWYAYRVKA 7166

Query: 1886 LKDTLTSRPAQGVVTTLENVSPPRRARVTDATETT-----------ITISWRTKTE---T 1931
            L     S+P++          P    +  D  E             +T+   TK E   T
Sbjct: 7167 LNRQGASKPSR----------PTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPAT 7216

Query: 1932 ITGFQVDAVPANGQTPIQRTIKPDVR----------SYTITGLQPGTDYKIYLYTLNDNA 1981
            +TG      P    T     +K D R          + TI   +        +  +N   
Sbjct: 7217 VTG---KPEPKITWTKADMILKQDKRITIENVPKKSTVTIVDSKRSDTGTYIIEAVNVCG 7273

Query: 1982 RSSPVV-IDASTAIDAPSNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPR 2036
            R++ VV ++       P+       T  S L++W PPR    ++IT Y+++     S   
Sbjct: 7274 RATAVVEVNVLDKPGPPAAFDITDVTNESCLLTWNPPRDDGGSKITNYVVERRATDS--- 7330

Query: 2037 EVVPRPRPGV--TEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQKTPFVTHPGY 2094
            EV  +    V  T    T L P  EY   V A       E + G  + VQ +P      +
Sbjct: 7331 EVWHKLSSTVKDTNFKATKLIPNKEYIFRVAA-------ENMYGVGEPVQASPITAKYQF 7383

Query: 2095 D 2095
            D
Sbjct: 7384 D 7384



 Score = 58.2 bits (139), Expect = 1e-07
 Identities = 314/1663 (18%), Positives = 573/1663 (34%), Gaps = 254/1663 (15%)

Query: 611   PVEVFITETPSQP-----------NSHPIQWNAPQPS---HISKYILRWRPKNSVGRWKE 656
             P+ V     PS+P           +S  + W+ P+ +    I+ Y +  R + S   WK 
Sbjct: 21151 PITVITLGPPSKPKGPIRFDEIKADSVILSWDVPEDNGGGEITCYSIEKR-ETSQTNWKM 21209

Query: 657   ATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETT 716
                     ++ +  L     Y+ ++ +  +YG              S P+ S+ +  +  
Sbjct: 21210 VCSSVARTTFKVPNLVKDAEYQFRVRAENRYG-------------VSQPLVSSIIVAKHQ 21256

Query: 717   PFSPLVATSESVTEITASSFVVSW----VSASDTVSGFRVEYELSEEGDEPQYLDLPSTA 772
                P       +  +T+    ++W          V+GF VE +        +    P + 
Sbjct: 21257 FRIPGPPGKPVIYNVTSDGMSLTWDAPVYDGGSEVTGFHVEKKERNSILWQKVNTSPISG 21316

Query: 773   TSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDP--TVDQVDDT--SIV 828
                    L+ G  Y   VY  +  G  S     S+ T   +P DP  T D +D T  +I 
Sbjct: 21317 REYRATGLVEGLDYQFRVYAENSAGLSSPS-DPSKFTLAVSPVDPPGTPDYIDVTRETIT 21375

Query: 829   VRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETAN-SVTLSDLQPGVQYNITIYA- 882
             ++W+ P     + I GY I      E      N  + +    T++ L PG +Y   I A 
Sbjct: 21376 LKWNPPLRDGGSKIVGYSIEKRQGNE-RWVRCNFTDVSECQYTVTGLSPGDRYEFRIIAR 21434

Query: 883   -----VEENQESTPVVIQQETTGTPRSDTVPSPRD---LQFVEVTDVKVTIMWTPPESAV 934
                  +    +S+ +++ ++    P  +  P   D   ++  E   +K  +   P    V
Sbjct: 21435 NAVGTISPPSQSSGIIMTRDENVPPIVEFGPEYFDGLIIKSGESLRIKALVQGRPVPR-V 21493

Query: 935   TGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYFK--------VFAVSHGRES 986
             T ++  V              I +    E+T +    + + +        V+ V     S
Sbjct: 21494 TWFKDGV-------------EIEKRMNMEITDVLGSTSLFVRDATRDHRGVYTVEAKNAS 21540

Query: 987   KPLTAQQTTKL-DAPTN----LQFVNETDSTVLVRWTPPR----AQITGYRLTVGLTRRG 1037
                 A+   K+ D P      ++F N T   + + W  P     A IT Y +    T R 
Sbjct: 21541 GSAKAEIKVKVQDTPGKVVGPIRFTNITGEKMTLWWDAPLNDGCAPITHYIIEKRETSRL 21600

Query: 1038  QPRQYNVGPSVSKYPLRNLQPASEYTVSLVAI------KGNQESPKATGVFTTLQPGSSI 1091
                          Y    L   +EY   + A+      +     P    +  T+     I
Sbjct: 21601 AWALIEDKCEAQSYTAIKLINGNEYQFRVSAVNKFGVGRPLDSDPVVAQIQYTVPDAPGI 21660

Query: 1092  PPYNTEVTETTIVITWTPAPRIG------FKLGVRPSQGGEAPREVTSDSGS---IVVSG 1142
             P   + +T  +I +TW      G      + L  R  +     + ++    S     V+G
Sbjct: 21661 PE-PSNITGNSITLTWARPESDGGSEIQQYILERREKKSTRWVKVISKRPISETRFKVTG 21719

Query: 1143  LTPGVEYVYTIQVLRDGQERDAPIVNKVVT---PLSPPTNLHLEANPDTGVLTVSWERST 1199
             LT G EY + +          A  +++++    P++PP    +    DT   TVS E S 
Sbjct: 21720 LTEGNEYEFHVMAENAAGVGPASGISRLIKCREPVNPPGPPTVVKVTDTSKTTVSLEWSK 21779

Query: 1200  TP-----DITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKD-- 1252
                    +I GY I     +    + +       ++  T  +L  G EY   V  +    
Sbjct: 21780 PVFDGGMEIIGYIIEMCKADLGDWHKVNAEACV-KTRYTVTDLQAGEEYKFRVSAINGAG 21838

Query: 1253  DKESVPISDTI-------IPEVPQLTDLSFVDITDSSIGLR--------------WTPLN 1291
               +S  ++ TI        PE+    +     +  +   +R              W+  +
Sbjct: 21839 KGDSCEVTGTIKAVDRLTAPELDIDANFKQTHVVRAGASIRLFIAYQGRPTPTAVWSKPD 21898

Query: 1292  SSTIIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTT 1351
             S+  +   I    +   + + E+   +  G YT+T            +   +G +S   T
Sbjct: 21899 SNLSLRADIHTTDSFSTLTV-ENCNRNDAGKYTLT------------VENNSGSKSITFT 21945

Query: 1352  LTQQTAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAE---LSIS 1408
             +       PP  + F ++   +  + W   P +D    +  Y   K E        +S  
Sbjct: 21946 VKVLDTPGPPGPITFKDVTRGSATLMW-DAPLLDGGARIHHYVVEKREASRRSWQVISEK 22004

Query: 1409  PSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDS----PTGIDFSDITANS 1464
              +     + +L  G  Y   VS+V E     P    +          P  +D  D + +S
Sbjct: 22005 CTRQIFKVNDLAEGVPYYFRVSAVNEYGVGEPYEMPEPIVATEQPAPPRRLDVVDTSKSS 22064

Query: 1465  FTVHWIAPR----ATITGYRIRHHPEHFSGRPREDRVPHSRN-SITLTNLTPGTEYVVSI 1519
               + W+ P     + ITGY +    +   G        H++  + T+  L   TEY   +
Sbjct: 22065 AVLAWLKPDHDGGSRITGYLLEMRQK---GSDFWVEAGHTKQLTFTVERLVEKTEYEFRV 22121

Query: 1520  VALNGREESPLLIGQQSTVSDVPR-----DLEVV--------AATPTSL---LISWDAPA 1563
              A N    S       S +   P+     DL  +        A +P ++   +    AP 
Sbjct: 22122 KAKNDAGYSEPREAFSSVIIKEPQIEPTADLTGITNQLITCKAGSPFTIDVPISGRPAPK 22181

Query: 1564  VTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVD--YTITVYAVTGRGDSPAS 1621
             VT +   +   ET   S     T    ++T T+     G    Y +T+       ++ A 
Sbjct: 22182 VTWKLEEMRLKETDRVS----ITTTKDRTTLTVKDSMRGDSGRYFLTL-------ENTAG 22230

Query: 1622  SKPISINYRTEIDKPSQM----QVTDVQDNSISVKWLP----SSSPVTGYRVTTTPKNGP 1673
              K  S+     I +P  +    +V+ V   S  + W        + +T Y +    ++G 
Sbjct: 22231 VKTFSVTV-VVIGRPGPVTGPIEVSSVSAESCVLSWGEPKDGGGTEITNY-IVEKRESGT 22288

Query: 1674  GPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAV------TNIDRPK 1727
                +   +   +T++ +  L   +EY   V ++N  G S+PL    +           P 
Sbjct: 22289 TAWQLVNSSVKRTQIKVTHLTKYMEYSFRVSSENRFGVSKPLESAPIIAEHPFVPPSAPT 22348

Query: 1728  GLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGE----EDTAELQGL 1783
                   V  +++ I WE P        + Y   +   + +    + +    E   ++ GL
Sbjct: 22349 RPEVYHVSANAMSIRWEEPYHDGGSKIIGYWVEKKERNTILWVKENKVPCLECNYKVTGL 22408

Query: 1784  RPGSEYTVSVVALH------DDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPP- 1836
               G EY     AL+          S+P++      + AP   + T VT +++S  W+ P 
Sbjct: 22409 VEGLEYQFRTYALNAAGVSKASEASRPIMA--QNPVDAPGRPEVTDVTRSTVSLIWSAPA 22466

Query: 1837  ---NVQLTGYRVRVTPKEKTGP---MKEINLAPDSSSVVVSGLMVATKYEVSVYALKDT- 1889
                  ++ GY +   P  + G    +K        +   V+ L     YE  V A     
Sbjct: 22467 YDGGSKVVGYIIERKPVSEVGDGRWLKCNYTIVSDNFFTVTALSEGDTYEFRVLAKNAAG 22526

Query: 1890  LTSRPAQ--GVVTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVP------ 1941
             + S+ ++  G VT  +  +PP+     DA      ++ R  ++ +    V   P      
Sbjct: 22527 VISKGSESTGPVTCRDEYAPPKAE--LDARLHGDLVTIRAGSDLVLDAAVGGKPEPKIIW 22584

Query: 1942  ANGQTPIQRTIKPDV-----RSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDA 1996
               G   +    K  +     R+  +      +D   Y  T+  NA  +  V      +D+
Sbjct: 22585 TKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSGKYTLTVK-NASGTKAVSVMVKVLDS 22643

Query: 1997  P---SNLRFLATTPNSLLVSWQPPR----ARITGYIIKYEKPGSPPREVVPRPRPGVTEA 2049
             P     L     T     ++W  P+    A IT YI++  +       +V    P ++  
Sbjct: 22644 PGPCGKLTVSRVTQEKCTLAWSLPQEDGGAEITHYIVERRETSRLNWVIVEGECPTLS-Y 22702

Query: 2050  TITGLEPGTEYTIYVIALKN-----NQKSEPLIGRKKTVQKTP 2087
              +T L    EY   V A+         +SEP++ R      +P
Sbjct: 22703 VVTRLIKNNEYIFRVRAVNKYGPGVPVESEPIVARNSFTIPSP 22745



 Score = 55.5 bits (132), Expect = 6e-07
 Identities = 128/535 (23%), Positives = 202/535 (37%), Gaps = 90/535 (16%)

Query: 593   GIGEWHCQPLQTYPSSSGPVEVFITETPSQP-------NSHPIQWNAPQ---PSHISKYI 642
             GIGE    PL + P ++  +   +   P +P       NS  + W  P+    S ++ Y 
Sbjct: 9801  GIGE----PLDSEPETARNL-FSVPGAPDKPTVSSVTRNSMTVNWEEPEYDGGSPVTGYW 9855

Query: 643   LRWRPKNSVGRWK-------EATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRF 695
             L  +   S  RWK       +A   G   SY + GL  G  Y+ ++ +I   G    +  
Sbjct: 9856  LEMKDTTSK-RWKRVNRDPIKAMTLGV--SYKVTGLIEGSDYQFRVYAINAAGVGPASL- 9911

Query: 696   DFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWV----SASDTVSGFR 751
                    S P T+        P +P       VT+ T SS  + W          V+G+ 
Sbjct: 9912  ------PSDPATARD------PIAPPGPPFPKVTDWTKSSADLEWSPPLKDGGSKVTGYI 9959

Query: 752   VEYELSEEGDEP--QYLDLPSTATSVNIPDLLPGRKY-----IVNVYQISEDGEQSLILS 804
             VEY+  EEG E   +  D     T + +  L  G  Y      VN+  I E GE + ++ 
Sbjct: 9960  VEYK--EEGKEEWEKGKDKEVRGTKLVVTGLKEGAFYKFRVRAVNIAGIGEPGEVTDVIE 10017

Query: 805   TSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETA-- 862
                       PD  +D      IVV        I        P+V  +  E  LP+ A  
Sbjct: 10018 MKDRLVS---PDLQLDASVRDRIVVHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEATI 10074

Query: 863   ------NSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPSPRDLQFV 916
                   +S+ + + Q   Q   ++ A  E  E    +I            VP P    F+
Sbjct: 10075 ETTAISSSMVIKNCQRSHQGVYSLLAKNEAGERKKTIIVDVLD-------VPGPVGTPFL 10127

Query: 917   --EVTDVKVTIMWTPPE----SAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPG 970
                +T+    + W  PE    S +T Y ++    +          ++R   A V GL  G
Sbjct: 10128 AHNLTNESCKLTWFSPEDDGGSPITNYVIEKRESDRRAWTPVTYTVTRQN-ATVQGLIQG 10186

Query: 971   VTYYFKVFA---VSHG---RESKPLTAQQT-TKLDAPTNLQFVNETDSTVLVRWTPPR-- 1021
               Y+F++ A   +  G     S+ L  ++  T  + P +L+    T +TV + W PP+  
Sbjct: 10187 KAYFFRIAAENSIGMGPFVETSEALVIREPITVPERPEDLEVKEVTKNTVTLTWNPPKYD 10246

Query: 1022  --AQITGYRLTVGLTRRGQPRQYNVGPSVS-KYPLRNLQPAS--EYTVSLVAIKG 1071
               ++I  Y L   L    +  +      +S KY ++ L+     EY VS V I G
Sbjct: 10247 GGSEIINYVLESRLIGTEKFHKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVG 10301



 Score = 52.8 bits (125), Expect = 4e-06
 Identities = 80/336 (23%), Positives = 120/336 (35%), Gaps = 46/336 (13%)

Query: 602  LQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQP---SHISKYILRWRPKN-SVGRWKEA 657
            ++ Y   S P  + +T+  ++  S  + W+AP     S I+ Y++  R  +     W+E 
Sbjct: 8995 VEVYDRPSPPRNLAVTDIKAE--SCYLTWDAPLDNGGSEITHYVIDKRDASRKKAEWEEV 9052

Query: 658  TIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTP 717
            T       Y I  L P   YE ++ ++ +YG  +  + D         V  +       P
Sbjct: 9053 TNTAVEKRYGIWKLIPNGQYEFRVRAVNKYGISDECKSD-------KVVIQDPYRLPGPP 9105

Query: 718  FSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTA----- 772
              P V         T  S +VSW    D        Y L +  +   Y    S A     
Sbjct: 9106 GKPKVLAR------TKGSMLVSWTPPLDNGGSPITGYWLEKREEGSPYWSRVSRAPITKV 9159

Query: 773  ----TSVNIPDLLPGRKY-----IVNVYQISEDGEQSLILSTSQTTAPDAPPD-PTVDQV 822
                   N+P LL G KY      +N   I    E S          P  PP  P V   
Sbjct: 9160 GLKGVEFNVPRLLEGVKYQFRAMAINAAGIGPPSEPSDPEVAGDPIFPPGPPSCPEVKDK 9219

Query: 823  DDTSIVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPE---TANSVTLSDLQPGVQ 875
              +SI + W  P     +PI GY +            +N P+   T     + +L+   +
Sbjct: 9220 TKSSISLGWKPPAKDGGSPIKGYIVEMQEEGTTDWKRVNEPDKLITTCECVVPNLKELRK 9279

Query: 876  YNITIYAVEENQESTPVVIQQETTG-TPRSDTVPSP 910
            Y   + AV E  ES P     +TTG  P +D    P
Sbjct: 9280 YRFRVKAVNEAGESEP----SDTTGEIPATDIQEEP 9311



 Score = 48.5 bits (114), Expect = 8e-05
 Identities = 107/537 (19%), Positives = 187/537 (34%), Gaps = 65/537 (12%)

Query: 610   GPVEVFITETPSQPNSHPIQWNAPQP---SHISKYILRWRPKNSVGRWKEATIPGHLNSY 666
             GPV        ++ + H + W  P+    S ++ YI+  R  +    W   T      S+
Sbjct: 12203 GPVSDLKVSDVTKTSCH-VSWAPPENDGGSQVTHYIVEKREADRK-TWSTVTPEVKKTSF 12260

Query: 667   TIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSE 726
              +  L PG  Y  ++ ++ +YG           T    PV ++    E  P   L     
Sbjct: 12261 HVTNLVPGNEYYFRVTAVNEYG-------PGVPTDVPKPVLASDPLSEPDPPRKL----- 12308

Query: 727   SVTEITASSFVVSWV----SASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLP 782
              VTE+T +S  ++W+         + G+   Y   E+  +           S+ +  L  
Sbjct: 12309 EVTEMTKNSATLAWLPPLRDGGAKIDGYITSYREEEQPADRWTEYSVVKDLSLVVTGLKE 12368

Query: 783   GRKY-----IVNVYQISEDGEQSLILSTSQTTAPD---APPDPTVDQVDDTSIVVRWSRP 834
             G+KY       N   +S   E   +    +   P     P   T+       I       
Sbjct: 12369 GKKYKFRVAARNAVGVSLPREAEGVYEAKEQLLPPKILMPEQITIKAGKKLRIEAHVYGK 12428

Query: 835   QAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDL--QPGVQYNITIYAVEENQESTPV 892
               P   ++      V  S   ++  ++++ + + D+  +    Y++T             
Sbjct: 12429 PHPTCKWKKGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIK 12488

Query: 893   VIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP----ESAVTGYRVDVIPVNLPG 948
             V+  +  G P+      P D+  ++      ++ W  P     S +T Y V+   V+  G
Sbjct: 12489 VVVMDAPGPPQ-----PPFDISDIDAD--ACSLSWHIPLEDGGSNITNYIVEKCDVS-RG 12540

Query: 949   EHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKL------DAPTN 1002
             +    L     T   V  L PG  Y F+V A +    S+PLT+ +            P N
Sbjct: 12541 DWVTALASVTKTSCRVGKLIPGQEYIFRVRAENRFGISEPLTSPKMVAQFPFGVPSEPKN 12600

Query: 1003  LQFVNETDSTVLVRWTPPRAQ----ITGYRLTVGLTRRGQPRQYNVGPSV---SKYPLRN 1055
              +        + V W  P +     I GY   +    R          ++   ++YP   
Sbjct: 12601 ARVTKVNKDCIFVAWDRPDSDGGSPIIGY--LIERKERNSLLWVKANDTLVRSTEYPCAG 12658

Query: 1056  LQPASEYTVSLVAIKGNQESP--KATGVFTTLQPGSSIPPYNTE---VTETTIVITW 1107
             L    EY+  + A+     SP  K T   T   P    PP   E   VT++T+ + W
Sbjct: 12659 LVEGLEYSFRIYALNKAGSSPPSKPTEYVTARMPVD--PPGKPEVIDVTKSTVSLIW 12713



 Score = 43.9 bits (102), Expect = 0.002
 Identities = 50/204 (24%), Positives = 83/204 (40%), Gaps = 22/204 (10%)

Query: 717   PFSPLVATSESVTEITASSFVVSWVSASDT----VSGFRVEYELSEEGDEPQYLDLPSTA 772
             P  P+V     +  +  +S V+SW   +D     ++ + VE   ++EG E Q +    + 
Sbjct: 24229 PTGPIV-----IEALLKNSAVISWKPPADDGGSWITNYVVEKCEAKEGAEWQLVSSAISV 24283

Query: 773   TSVNIPDLLPGRKYIV-----NVYQISEDGE-QSLILSTSQTTAPDAPPDPTVDQVDDTS 826
             T+  I +L     Y       N + IS+  E  S+++  S    P AP  PT+  V   S
Sbjct: 24284 TTCRIVNLTENAGYYFRVSAQNTFGISDPLEVSSVVIIKSPFEKPGAPGKPTITAVTKDS 24343

Query: 827   IVVRWSRPQ----APITGYRIVYSPSVEGSSTELNLPETANSV-TLSDLQPGVQYNITIY 881
              VV W  P     A I  Y +      +     +   E   +V ++ +L  G++Y   + 
Sbjct: 24344 CVVAWKPPASDGGAKIRNYYLEKREKKQNKWISVTTEEIRETVFSVKNLIEGLEYEFRVK 24403

Query: 882   AVEENQESTPVVIQQETTGTPRSD 905
                   ES    I +    TP+SD
Sbjct: 24404 CENLGGESEWSEISEPI--TPKSD 24425



 Score = 41.2 bits (95), Expect = 0.013
 Identities = 92/413 (22%), Positives = 157/413 (38%), Gaps = 51/413 (12%)

Query: 1376  VTWAPPPSID---LTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSV 1432
             ++W PP       +TN++V     K   +   +S + S     + NL     Y   VS+ 
Sbjct: 24245 ISWKPPADDGGSWITNYVVEKCEAKEGAEWQLVSSAISVTTCRIVNLTENAGYYFRVSAQ 24304

Query: 1433  YEQHESTPLRGRQKTGLDSPTGID-------FSDITANSFTVHWIAPRATITGYRIRHHP 1485
                  S PL       + SP            + +T +S  V W  P A+  G +IR++ 
Sbjct: 24305 NTFGISDPLEVSSVVIIKSPFEKPGAPGKPTITAVTKDSCVVAW-KPPASDGGAKIRNYY 24363

Query: 1486  EHFSGRPREDRVPHSRNSITLT-----NLTPGTEYVVSIVA--LNGREESPLLIGQQSTV 1538
                  + +   +  +   I  T     NL  G EY   +    L G  E   +    +  
Sbjct: 24364 LEKREKKQNKWISVTTEEIRETVFSVKNLIEGLEYEFRVKCENLGGESEWSEISEPITPK 24423

Query: 1539  SDVP----------RDLEVVAATPTSLLISWDA-PAVTVRYYRITYGET----GGNSPVQ 1583
             SDVP          R+L V   +  +L+      P   V++YR   G+     G    +Q
Sbjct: 24424 SDVPIQAPHFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYR--QGKEIIADGLKYRIQ 24481

Query: 1584  EFTVPGSKSTATISGLKPGVDYTITVYAV--TGRGDSPASSKPISINYRTEIDKPSQMQ- 1640
             EF   G      I+ +    D   TVY V  T +G S + +  + +    +I  P  ++ 
Sbjct: 24482 EFK--GGYHQLIIASV---TDDDATVYQVRATNQGGSVSGTASLEVEVPAKIHLPKTLEG 24536

Query: 1641  ---VTDVQDNSISVKWLPSSS---PVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQ 1694
                V  ++   +S+K +P S    PV  ++      +  G  +        + +   G++
Sbjct: 24537 MGAVHALRGEVVSIK-IPFSGKPDPVITWQKGQDLIDNNGHYQVIVTRSFTSLVFPNGVE 24595

Query: 1695  PTVEYVVSVYAQNPSGESQPLVQTAVTNI-DRPKGLAFTDVDVDSIKIAWESP 1746
                     V A+N  G  Q  V+  V ++ D P+G+  +DV  DS+ + W  P
Sbjct: 24596 RKDAGFYVVCAKNRFGIDQKTVELDVADVPDPPRGVKVSDVSRDSVNLTWTEP 24648



 Score = 37.7 bits (86), Expect = 0.14
 Identities = 36/131 (27%), Positives = 53/131 (40%), Gaps = 8/131 (6%)

Query: 894   IQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPE----SAVTGYRVDVIPVNLPGE 949
             I Q+T     +D    PR ++  +V+   V + WT P     S +T Y V+        E
Sbjct: 24612 IDQKTVELDVADVPDPPRGVKVSDVSRDSVNLTWTEPASDGGSKITNYIVEKCATT--AE 24669

Query: 950   HGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQ--TTKLDAPTNLQFVN 1007
                R+  +R T   V  L    +Y F+V A +    SKP    +   TK D    + +  
Sbjct: 24670 RWLRVGQARETRYTVINLFGKTSYQFRVIAENKFGLSKPSEPSEPTITKEDKTRAMNYDE 24729

Query: 1008  ETDSTVLVRWT 1018
             E D T  V  T
Sbjct: 24730 EVDETREVSMT 24740



 Score = 35.0 bits (79), Expect = 0.90
 Identities = 38/169 (22%), Positives = 71/169 (42%), Gaps = 17/169 (10%)

Query: 1610  YAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWL-PSS---SPVTGYRV 1665
             Y V  +       K + ++     D P  ++V+DV  +S+++ W  P+S   S +T Y V
Sbjct: 24602 YVVCAKNRFGIDQKTVELDVADVPDPPRGVKVSDVSRDSVNLTWTEPASDGGSKITNYIV 24661

Query: 1666  TTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPL--VQTAVTNI 1723
                        +   A   +T  T+  L     Y   V A+N  G S+P    +  +T  
Sbjct: 24662 EKCATTAERWLRVGQA--RETRYTVINLFGKTSYQFRVIAENKFGLSKPSEPSEPTITKE 24719

Query: 1724  DRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPD 1772
             D+ + + + D +VD  +        +VS  + ++SS ++   +   A D
Sbjct: 24720 DKTRAMNY-DEEVDETR--------EVSMTKASHSSTKELYEKYMIAED 24759


>gi|119220552 sidekick 1 [Homo sapiens]
          Length = 2213

 Score =  166 bits (419), Expect = 3e-40
 Identities = 280/1342 (20%), Positives = 500/1342 (37%), Gaps = 195/1342 (14%)

Query: 737  VVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTA---TSVNIPDLLPGRKYIVNVYQI 793
            V+SWV   D  S          E + P  + L +     T V +  L P R Y   V  +
Sbjct: 687  VLSWVRPFDGNSPILYYIVELSENNSPWKVHLSNVGPEMTGVTVSGLTPARTYQFRVCAV 746

Query: 794  SEDGEQSLILSTSQTTAPDAPPDPTVDQV-----DDTSIVVRWSRP---------QAPIT 839
            +E G       TS+   P+ PP      +      + SI+V+W  P         +  I 
Sbjct: 747  NEVGRGQYSAETSRLMLPEEPPSAPPKNIVASGRTNQSIMVQWQPPPETEHNGVLRGYIL 806

Query: 840  GYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETT 899
             YR+   P  E     +  PE  N   ++DL    QY I + A   N     V  +  T 
Sbjct: 807  RYRLAGLPG-EYQQRNITSPE-VNYCLVTDLIIWTQYEIQVAAY--NGAGLGVFSRAVTE 862

Query: 900  GTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAV-----TGYRVDVIPVNLPGEHGQRL 954
             T +      P+++Q   V    +  +W PP          GY++   P + P E    +
Sbjct: 863  YTLQGVPTAPPQNVQTEAVNSTTIQFLWNPPPQQFINGINQGYKLLAWPADAP-EAVTVV 921

Query: 955  PISRN----TFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQ----QTTKLDAPTNLQFV 1006
             I+ +        +T L     Y+  V   +   +  P T Q    Q  K  A  +L F 
Sbjct: 922  TIAPDFHGVHHGHITNLKKFTAYFTSVLCFTTPGDGPPSTPQLVWTQEDKPGAVGHLSFT 981

Query: 1007 NETDSTVLVRWTPPRAQ---ITGYRLTVGLTRRGQPR-QYNVGPSVSKYPLRNLQPASEY 1062
               D+++ V W  P  +   ITGY+++  +  R   R  + +  +  +Y ++ L   + Y
Sbjct: 982  EILDTSLKVSWQEPLEKNGIITGYQISWEVYGRNDSRLTHTLNSTTHEYKIQGLSSLTTY 1041

Query: 1063 TVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPAPRIGFKLGVRPS 1122
            T+ + A+     +   TG+ T+    S +PP         ++   +P       L  RP 
Sbjct: 1042 TIDVAAV-----TAVGTGLVTSSTISSGVPPDLPGAPSNLVISNISPR---SATLQFRPG 1093

Query: 1123 QGGEA------------------------PREVTSDSGSIVVSGLTPGVEYVYTI-QVLR 1157
              G+                           E   D+  + +  LTP   Y + + QV  
Sbjct: 1094 YDGKTSISRWIVEGQVGAIGDEEEWVTLYEEENEPDAQMLEIPNLTPYTHYRFRMKQVNI 1153

Query: 1158 DGQERDAPIVNKVVTPLSP----PTNLHLEANPDTGVLTVSW------ERSTTPDITGYR 1207
             G    +P    + T  +P    PT++ +    +T  L + W      + +  P+  GYR
Sbjct: 1154 VGPSPYSPSSRVIQTLQAPPDVAPTSVTVRTASETS-LRLRWVPLPDSQYNGNPESVGYR 1212

Query: 1208 ITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVK-------------DDK 1254
            I    ++ Q     + V    +   T + L   +EY + +                   +
Sbjct: 1213 IKYWRSDLQSSAVAQVVSDRLEREFTIEELEEWMEYELQMQAFNAVGAGPWSEVVRGRTR 1272

Query: 1255 ESVPISDTIIPEVPQLTDLSFVDITDSSIGLRWTPL----NSSTIIGYRITVVAAG-EGI 1309
            ESVP   +  PE     ++S   ++ + I L WT +     +  I+GY+I   A   +  
Sbjct: 1273 ESVP---SAAPE-----NVSAEAVSSTQILLTWTSVPEQDQNGLILGYKILFRAKDLDPE 1324

Query: 1310 PIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTT-----LTQQTAVPPPTDL 1364
            P       +      + GL   + Y++ V+     G   P+T      T+  A  PP  L
Sbjct: 1325 PRSHIVRGNHTQSALLAGLRKFVLYELQVLAFTRIGNGVPSTPLILERTKDDAPGPPVRL 1384

Query: 1365 RFTNIGPDTMRVTWAPP--PSIDLTNFLVRYSPVKNE-EDVAELSISPSDNAVVLTNLLP 1421
             F  +   ++R+ W PP  P+  +  + + Y    +       + +  +      T+L P
Sbjct: 1385 VFPEVRLTSVRIVWQPPEEPNGIILGYQIAYRLASSSPHTFTTVEVGATVRQFTATDLAP 1444

Query: 1422 GTEYVVSVSSVYEQHESTPLRG-------RQKTGLDSPTGIDFSDITANSFTVHWIAPRA 1474
             + Y+  +S+   Q    PL         R++        +  +++TA S  + W+    
Sbjct: 1445 ESAYIFRLSAKTRQGWGEPLEATVITTEKRERPAPPRELLVPQAEVTARSLRLQWVP--G 1502

Query: 1475 TITGYRIRHHPEHFSGRPR------EDRVPHSRNSITLTNLTPGTEYVVSIVALNGREES 1528
            +     IR+        PR         + H   +  +  L P T Y + + A N   +S
Sbjct: 1503 SDGASPIRYFTMQVRELPRGEWQTYSSSISHEATACVVDRLRPFTSYKLRLKATNDIGDS 1562

Query: 1529 PLLIGQQ--STVSDVPRDLE-VVAATP---TSLLISWDAPA-----VTVRYYRITYG--- 1574
                  +  +T+ DVP +    V+ATP   +S+LI W  P        ++ YRI Y    
Sbjct: 1563 DFSSETEAVTTLQDVPGEPPGSVSATPHTTSSVLIQWQPPRDESLNGLLQGYRIYYRELE 1622

Query: 1575 -ETGGNSPVQ----------------EFTVPGSKSTAT---ISGLKPGVDYTITVYAVTG 1614
             E G  +  +                 F    S ST+T   ++ LK    Y + + A   
Sbjct: 1623 YEAGSGTEAKTLKNPIALHAELTAQSSFKTVNSSSTSTMCELTHLKKYRRYEVIMTAYNI 1682

Query: 1615 RGDSPASSK-PISINYRTEIDKPSQMQVTDVQDNSISVKWLP-----SSSPVTGYRVTTT 1668
             G+SPAS+   + +        P  +QVT +  + + V W P      +  + GY++   
Sbjct: 1683 IGESPASAPVEVFVGEAAPAMAPQNVQVTPLTASQLEVTWDPPPPESQNGNIQGYKIYYW 1742

Query: 1669 PKNGPGPT-KTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGE---SQPLV-QTAVTNI 1723
              +    T K K     +  + ++ L    +Y+VS+ A N +G+   S P   +T     
Sbjct: 1743 EADSQNETEKMKVLFLPEPVVRLKNLTSHTKYLVSISAFNAAGDGPKSDPQQGRTHQAAP 1802

Query: 1724 DRPKGLAFTDVDVDSIKIAWESP---QGQVSRYRVTYS--SPEDGIHELFPAP--DGEED 1776
              P  LAF+++   ++ ++W  P    G +  YRV Y   +P  G+ ++         + 
Sbjct: 1803 GAPSFLAFSEITSTTLNVSWGEPAAANGILQGYRVVYEPLAPVQGVSKVVTVEVRGNWQR 1862

Query: 1777 TAELQGLRPGSEYTVSV----VALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQ 1832
              +++ L  G  Y   V    +    ++++    G    +  +P D+  T+ + + L+ Q
Sbjct: 1863 WLKVRDLTKGVTYFFRVQARTITYGPELQANITAGPAEGSPGSPRDVLVTK-SASELTLQ 1921

Query: 1833 WT---PPNVQLTGYRVRVTPKEK---TGPMKEINLAPDSSSVVVSGLMVATKYEVSVYAL 1886
            WT     +   TGY +   P ++      +K+I  +  S ++ +  L     YE  V A+
Sbjct: 1922 WTEGHSGDTPTTGYVIEARPSDEGLWDMFVKDIPRSATSYTLSLDKLRQGVTYEFRVVAV 1981

Query: 1887 KDTLTSRPAQGVVTTLENVSPP 1908
             +     P+         V  P
Sbjct: 1982 NEAGYGEPSNPSTAVSAQVEAP 2003



 Score =  137 bits (346), Expect = 1e-31
 Identities = 248/1135 (21%), Positives = 431/1135 (37%), Gaps = 162/1135 (14%)

Query: 1043 NVGPSVSKYPLRNLQPASEYTVSLVAIKG---NQESPKATGVFTTLQPGSSIPPYNTEV- 1098
            NVGP ++   +  L PA  Y   + A+      Q S + + +    +P S+ PP N    
Sbjct: 720  NVGPEMTGVTVSGLTPARTYQFRVCAVNEVGRGQYSAETSRLMLPEEPPSA-PPKNIVAS 778

Query: 1099 --TETTIVITWTPAPRI-------GFKLGVRPS--QGGEAPREVTS-DSGSIVVSGLTPG 1146
              T  +I++ W P P         G+ L  R +   G    R +TS +    +V+ L   
Sbjct: 779  GRTNQSIMVQWQPPPETEHNGVLRGYILRYRLAGLPGEYQQRNITSPEVNYCLVTDLIIW 838

Query: 1147 VEYVYTIQVLRDGQERDAPIVNKVVT-------PLSPPTNLHLEANPDTGVLTVSWERST 1199
             +Y   +            + ++ VT       P +PP N+  EA   T +  + W    
Sbjct: 839  TQYEIQVAAYNGA---GLGVFSRAVTEYTLQGVPTAPPQNVQTEAVNSTTIQFL-WNPPP 894

Query: 1200 TPDITG----YRITTTPTNGQQGNSLEEV------VHADQSSCTFDNLSPGLEYNVSVYT 1249
               I G    Y++   P +  +  ++  +      VH    +    NL     Y  SV  
Sbjct: 895  QQFINGINQGYKLLAWPADAPEAVTVVTIAPDFHGVHHGHIT----NLKKFTAYFTSVLC 950

Query: 1250 VKDDKESVPISDTII----PEVPQLTDLSFVDITDSSIGLRWT-PLNSSTII-GYRITVV 1303
                 +  P +  ++     +   +  LSF +I D+S+ + W  PL  + II GY+I+  
Sbjct: 951  FTTPGDGPPSTPQLVWTQEDKPGAVGHLSFTEILDTSLKVSWQEPLEKNGIITGYQISWE 1010

Query: 1304 AAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAVPP--- 1360
              G         ++S+   Y + GL     Y I V  +   G    T+ T  + VPP   
Sbjct: 1011 VYGRNDSRLTHTLNSTTHEYKIQGLSSLTTYTIDVAAVTAVGTGLVTSSTISSGVPPDLP 1070

Query: 1361 --PTDLRFTNIGPDTMRVTWAP--PPSIDLTNFLV--RYSPVKNEED---VAELSISPSD 1411
              P++L  +NI P +  + + P       ++ ++V  +   + +EE+   + E    P  
Sbjct: 1071 GAPSNLVISNISPRSATLQFRPGYDGKTSISRWIVEGQVGAIGDEEEWVTLYEEENEPDA 1130

Query: 1412 NAVVLTNLLPGTEYVVSVSSVY------EQHESTPLRGRQKTGLDSPTGIDFSDITANSF 1465
              + + NL P T Y   +  V           S  ++  Q     +PT +     +  S 
Sbjct: 1131 QMLEIPNLTPYTHYRFRMKQVNIVGPSPYSPSSRVIQTLQAPPDVAPTSVTVRTASETSL 1190

Query: 1466 TVHWIA-------PRATITGYRIRHHPEHFSGRPREDRVPHS-RNSITLTNLTPGTEYVV 1517
             + W+              GYRI++             V        T+  L    EY +
Sbjct: 1191 RLRWVPLPDSQYNGNPESVGYRIKYWRSDLQSSAVAQVVSDRLEREFTIEELEEWMEYEL 1250

Query: 1518 SIVALNGREESP---LLIGQ--QSTVSDVPRDLEVVAATPTSLLISWDAPAVT-----VR 1567
             + A N     P   ++ G+  +S  S  P ++   A + T +L++W +         + 
Sbjct: 1251 QMQAFNAVGAGPWSEVVRGRTRESVPSAAPENVSAEAVSSTQILLTWTSVPEQDQNGLIL 1310

Query: 1568 YYRITYGETGGNSPVQEFTVPGSKS-TATISGLKPGVDYTITVYAVTGRGDSPASSKPIS 1626
             Y+I +     +   +   V G+ + +A ++GL+  V Y + V A T  G+   S+ P+ 
Sbjct: 1311 GYKILFRAKDLDPEPRSHIVRGNHTQSALLAGLRKFVLYELQVLAFTRIGNGVPST-PLI 1369

Query: 1627 INYRTEIDKPS---QMQVTDVQDNSISVKWLPSSSP---VTGYRVT-TTPKNGPGPTKTK 1679
            +  RT+ D P    ++   +V+  S+ + W P   P   + GY++      + P    T 
Sbjct: 1370 LE-RTKDDAPGPPVRLVFPEVRLTSVRIVWQPPEEPNGIILGYQIAYRLASSSPHTFTTV 1428

Query: 1680 TAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDR-----PKGLAFTDV 1734
              G    + T   L P   Y+  + A+   G  +PL  T +T   R     P+ L     
Sbjct: 1429 EVGATVRQFTATDLAPESAYIFRLSAKTRQGWGEPLEATVITTEKRERPAPPRELLVPQA 1488

Query: 1735 DVD--SIKIAWESPQGQVSRYRVTYSSPED---GIHELFPAPDGEEDTA-ELQGLRPGSE 1788
            +V   S+++ W       S  R       +   G  + + +    E TA  +  LRP + 
Sbjct: 1489 EVTARSLRLQWVPGSDGASPIRYFTMQVRELPRGEWQTYSSSISHEATACVVDRLRPFTS 1548

Query: 1789 YTVSVVALHD----DMESQPLIGTQSTAIPA--PTDLKFTQVTPTSLSAQWTPP-----N 1837
            Y + + A +D    D  S+    T    +P   P  +  T  T +S+  QW PP     N
Sbjct: 1549 YKLRLKATNDIGDSDFSSETEAVTTLQDVPGEPPGSVSATPHTTSSVLIQWQPPRDESLN 1608

Query: 1838 VQLTGYRVRVTPKE---------KT--------------GPMKEINLAPDSSSVVVSGLM 1874
              L GYR+     E         KT                 K +N +  S+   ++ L 
Sbjct: 1609 GLLQGYRIYYRELEYEAGSGTEAKTLKNPIALHAELTAQSSFKTVNSSSTSTMCELTHLK 1668

Query: 1875 VATKYEVSVYA---LKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISW-----R 1926
               +YEV + A   + ++  S P +  V        P+  +VT  T + + ++W      
Sbjct: 1669 KYRRYEVIMTAYNIIGESPASAPVEVFVGEAAPAMAPQNVQVTPLTASQLEVTWDPPPPE 1728

Query: 1927 TKTETITGFQVDAVPANGQTPIQRTI-----KPDVRSYTITGLQPGTDYKIYLYTLN--- 1978
            ++   I G+++    A+ Q   ++       +P VR   +T     T Y + +   N   
Sbjct: 1729 SQNGNIQGYKIYYWEADSQNETEKMKVLFLPEPVVRLKNLTS---HTKYLVSISAFNAAG 1785

Query: 1979 DNARSSPVVIDASTAID-APSNLRFLATTPNSLLVSWQPPRAR---ITGYIIKYE 2029
            D  +S P       A   APS L F   T  +L VSW  P A    + GY + YE
Sbjct: 1786 DGPKSDPQQGRTHQAAPGAPSFLAFSEITSTTLNVSWGEPAAANGILQGYRVVYE 1840



 Score =  125 bits (315), Expect = 4e-28
 Identities = 240/1096 (21%), Positives = 396/1096 (36%), Gaps = 141/1096 (12%)

Query: 1056 LQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEV----TETTIVITWTPAP 1111
            +Q A  YT      +G   S  A+   T     S + P    V    T  T+    T  P
Sbjct: 545  IQDAGNYTCYAANTEG---SLNASATLTVWNRTSIVHPPEDHVVIKGTTATLHCGATHDP 601

Query: 1112 RIGFKLGVRPSQGGEAP----REVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIV 1167
            R+  +   +       P    R V    GS+++S    G    Y+ +++ +G        
Sbjct: 602  RVSLRYVWKKDNVALTPSSTSRIVVEKDGSLLISQTWSGDIGDYSCEIVSEGGNDSRMAR 661

Query: 1168 NKVVTPLSPPTNLHLEANPD-TGVLTVSWER---STTPDITGYRITTTPTNGQQGNSLEE 1223
             +V+     P NL +  N   +  + +SW R     +P +  Y I     N         
Sbjct: 662  LEVIELPHSPQNLLVSPNSSHSHAVVLSWVRPFDGNSPIL--YYIVELSENNSPWKVHLS 719

Query: 1224 VVHADQSSCTFDNLSPGLEYNVSVYTVKD---DKESVPISDTIIPEVPQLT---DLSFVD 1277
             V  + +  T   L+P   Y   V  V +    + S   S  ++PE P      ++    
Sbjct: 720  NVGPEMTGVTVSGLTPARTYQFRVCAVNEVGRGQYSAETSRLMLPEEPPSAPPKNIVASG 779

Query: 1278 ITDSSIGLRWTPL----NSSTIIGYRITVVAAG-EGIPIFEDFVDSSVGYYTVTGLEPGI 1332
             T+ SI ++W P     ++  + GY +    AG  G     +     V Y  VT L    
Sbjct: 780  RTNQSIMVQWQPPPETEHNGVLRGYILRYRLAGLPGEYQQRNITSPEVNYCLVTDLIIWT 839

Query: 1333 DYDISVITLINGG----ESAPTTLTQQTAVP--PPTDLRFTNIGPDTMRVTWAPPPSIDL 1386
             Y+I V      G      A T  T Q  VP  PP +++   +   T++  W PPP   +
Sbjct: 840  QYEIQVAAYNGAGLGVFSRAVTEYTLQ-GVPTAPPQNVQTEAVNSTTIQFLWNPPPQQFI 898

Query: 1387 TNFLVRYS----PVKNEEDVAELSISPSDNAVV---LTNLLPGTEYVVSVSSVYEQHEST 1439
                  Y     P    E V  ++I+P  + V    +TNL   T Y  SV       +  
Sbjct: 899  NGINQGYKLLAWPADAPEAVTVVTIAPDFHGVHHGHITNLKKFTAYFTSVLCFTTPGDGP 958

Query: 1440 PLRGRQK-TGLDSPTGI---DFSDITANSFTVHWIAP---RATITGYRIRHHPEHFSGRP 1492
            P   +   T  D P  +    F++I   S  V W  P      ITGY+I        GR 
Sbjct: 959  PSTPQLVWTQEDKPGAVGHLSFTEILDTSLKVSWQEPLEKNGIITGYQISWE---VYGR- 1014

Query: 1493 REDRVPHSRNSIT----LTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPRDLEVV 1548
             + R+ H+ NS T    +  L+  T Y + + A+        L+   +  S VP DL   
Sbjct: 1015 NDSRLTHTLNSTTHEYKIQGLSSLTTYTIDVAAVTAVGTG--LVTSSTISSGVPPDLP-- 1070

Query: 1549 AATPTSLLISWDAPAVTVRYYRITY------------GETGGNSPVQEFTVPGSKSTAT- 1595
               P++L+IS  +P      +R  Y            G+ G     +E+     +     
Sbjct: 1071 -GAPSNLVISNISPRSATLQFRPGYDGKTSISRWIVEGQVGAIGDEEEWVTLYEEENEPD 1129

Query: 1596 -----ISGLKPGVDYTITVYAVTGRGDSP--ASSKPISINYRTEIDKPSQMQVTDVQDNS 1648
                 I  L P   Y   +  V   G SP   SS+ I          P+ + V    + S
Sbjct: 1130 AQMLEIPNLTPYTHYRFRMKQVNIVGPSPYSPSSRVIQTLQAPPDVAPTSVTVRTASETS 1189

Query: 1649 ISVKWLP-------SSSPVTGYRVTTTPKNGPGPTKTKTAGPD-QTEMTIEGLQPTVEYV 1700
            + ++W+P        +    GYR+     +       +      + E TIE L+  +EY 
Sbjct: 1190 LRLRWVPLPDSQYNGNPESVGYRIKYWRSDLQSSAVAQVVSDRLEREFTIEELEEWMEYE 1249

Query: 1701 VSVYAQNP----------SGESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQV 1750
            + + A N            G ++  V +A       + ++ T + +    +  +   G +
Sbjct: 1250 LQMQAFNAVGAGPWSEVVRGRTRESVPSAAPENVSAEAVSSTQILLTWTSVPEQDQNGLI 1309

Query: 1751 SRYRVTYSSPEDGIHELFPAP------DGEEDTAELQGLRPGSEYTVSVVA---LHDDME 1801
              Y++ + + +     L P P           +A L GLR    Y + V+A   + + + 
Sbjct: 1310 LGYKILFRAKD-----LDPEPRSHIVRGNHTQSALLAGLRKFVLYELQVLAFTRIGNGVP 1364

Query: 1802 SQPLI--GTQSTAIPAPTDLKFTQVTPTSLSAQWTPP---NVQLTGYRVRVT-PKEKTGP 1855
            S PLI   T+  A   P  L F +V  TS+   W PP   N  + GY++           
Sbjct: 1365 STPLILERTKDDAPGPPVRLVFPEVRLTSVRIVWQPPEEPNGIILGYQIAYRLASSSPHT 1424

Query: 1856 MKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLEN---VSPPRRAR 1912
               + +         + L   + Y   + A        P +  V T E     +PPR   
Sbjct: 1425 FTTVEVGATVRQFTATDLAPESAYIFRLSAKTRQGWGEPLEATVITTEKRERPAPPRELL 1484

Query: 1913 VTDA--TETTITISWRTKTETITGF-----QVDAVPANGQTPIQRTIKPDVRSYTITGLQ 1965
            V  A  T  ++ + W   ++  +       QV  +P         +I  +  +  +  L+
Sbjct: 1485 VPQAEVTARSLRLQWVPGSDGASPIRYFTMQVRELPRGEWQTYSSSISHEATACVVDRLR 1544

Query: 1966 PGTDYKIYLYTLND------NARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPR- 2018
            P T YK+ L   ND      ++ +  V        + P ++     T +S+L+ WQPPR 
Sbjct: 1545 PFTSYKLRLKATNDIGDSDFSSETEAVTTLQDVPGEPPGSVSATPHTTSSVLIQWQPPRD 1604

Query: 2019 ----ARITGYIIKYEK 2030
                  + GY I Y +
Sbjct: 1605 ESLNGLLQGYRIYYRE 1620



 Score =  108 bits (269), Expect = 8e-23
 Identities = 229/1087 (21%), Positives = 408/1087 (37%), Gaps = 163/1087 (14%)

Query: 1138 IVVSGLTPGVEYVYTIQVLRD-GQERDAPIVNKVVTPLSPPT----NLHLEANPDTGVLT 1192
            + VSGLTP   Y + +  + + G+ + +   ++++ P  PP+    N+      +  ++ 
Sbjct: 728  VTVSGLTPARTYQFRVCAVNEVGRGQYSAETSRLMLPEEPPSAPPKNIVASGRTNQSIM- 786

Query: 1193 VSWERSTTPDITG--------YRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYN 1244
            V W+     +  G        YR+   P   QQ N    +   + + C   +L    +Y 
Sbjct: 787  VQWQPPPETEHNGVLRGYILRYRLAGLPGEYQQRN----ITSPEVNYCLVTDLIIWTQYE 842

Query: 1245 VSVYTVKDDKESV---PISDTIIPEVPQLT--DLSFVDITDSSIGLRWTPLNSSTIIG-- 1297
            + V         V    +++  +  VP     ++    +  ++I   W P     I G  
Sbjct: 843  IQVAAYNGAGLGVFSRAVTEYTLQGVPTAPPQNVQTEAVNSTTIQFLWNPPPQQFINGIN 902

Query: 1298 --YRITVVAAGEG-----IPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPT 1350
              Y++    A        + I  DF     G+  +T L+    Y  SV+     G+  P+
Sbjct: 903  QGYKLLAWPADAPEAVTVVTIAPDFHGVHHGH--ITNLKKFTAYFTSVLCFTTPGDGPPS 960

Query: 1351 T----LTQQTAVPPPTDLRFTNIGPDTMRVTWAPPPSID--LTNFLVRYSPVKNEEDVAE 1404
            T     TQ+        L FT I   +++V+W  P   +  +T + + +      +    
Sbjct: 961  TPQLVWTQEDKPGAVGHLSFTEILDTSLKVSWQEPLEKNGIITGYQISWEVYGRNDSRLT 1020

Query: 1405 LSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLD-----SPTGIDFSD 1459
             +++ + +   +  L   T Y + V++V              +G+      +P+ +  S+
Sbjct: 1021 HTLNSTTHEYKIQGLSSLTTYTIDVAAVTAVGTGLVTSSTISSGVPPDLPGAPSNLVISN 1080

Query: 1460 ITANSFTVHW---IAPRATITGYRIRHH------PEHFSGRPREDRVPHSRNSITLTNLT 1510
            I+  S T+ +      + +I+ + +          E +     E+  P ++  + + NLT
Sbjct: 1081 ISPRSATLQFRPGYDGKTSISRWIVEGQVGAIGDEEEWVTLYEEENEPDAQ-MLEIPNLT 1139

Query: 1511 PGTEY-----VVSIVALNGREESPLLIGQQSTVSDV-PRDLEVVAATPTSLLISWDAPAV 1564
            P T Y      V+IV  +    S  +I       DV P  + V  A+ TSL + W  P  
Sbjct: 1140 PYTHYRFRMKQVNIVGPSPYSPSSRVIQTLQAPPDVAPTSVTVRTASETSLRLRW-VPLP 1198

Query: 1565 TVRY--------YRITYGETG-GNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGR 1615
              +Y        YRI Y  +   +S V +      +   TI  L+  ++Y + + A    
Sbjct: 1199 DSQYNGNPESVGYRIKYWRSDLQSSAVAQVVSDRLEREFTIEELEEWMEYELQMQAFNAV 1258

Query: 1616 GDSPASSKPISINYRTEIDKPS----QMQVTDVQDNSISVKWLP-----SSSPVTGYRVT 1666
            G  P S     +  RT    PS     +    V    I + W        +  + GY++ 
Sbjct: 1259 GAGPWSEV---VRGRTRESVPSAAPENVSAEAVSSTQILLTWTSVPEQDQNGLILGYKIL 1315

Query: 1667 TTPKN-GPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQP-----LVQTAV 1720
               K+  P P      G       + GL+  V Y + V A    G   P     L +T  
Sbjct: 1316 FRAKDLDPEPRSHIVRGNHTQSALLAGLRKFVLYELQVLAFTRIGNGVPSTPLILERTKD 1375

Query: 1721 TNIDRPKGLAFTDVDVDSIKIAW---ESPQGQVSRYRVTYSSPEDGIHELFPAPDG---E 1774
                 P  L F +V + S++I W   E P G +  Y++ Y       H       G    
Sbjct: 1376 DAPGPPVRLVFPEVRLTSVRIVWQPPEEPNGIILGYQIAYRLASSSPHTFTTVEVGATVR 1435

Query: 1775 EDTAELQGLRPGSEYTVSVVALHDDMESQPL----IGTQSTAIPAPTD---LKFTQVTPT 1827
            + TA    L P S Y   + A       +PL    I T+    PAP     +   +VT  
Sbjct: 1436 QFTAT--DLAPESAYIFRLSAKTRQGWGEPLEATVITTEKRERPAPPRELLVPQAEVTAR 1493

Query: 1828 SLSAQWTPPN-----VQLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVS 1882
            SL  QW P +     ++    +VR  P+ +       +++ ++++ VV  L   T Y++ 
Sbjct: 1494 SLRLQWVPGSDGASPIRYFTMQVRELPRGEWQTYSS-SISHEATACVVDRLRPFTSYKLR 1552

Query: 1883 VYALKDTLTS--RPAQGVVTTLENV--SPPRRARVTDATETTITISWRTKTET-----IT 1933
            + A  D   S        VTTL++V   PP     T  T +++ I W+   +      + 
Sbjct: 1553 LKATNDIGDSDFSSETEAVTTLQDVPGEPPGSVSATPHTTSSVLIQWQPPRDESLNGLLQ 1612

Query: 1934 GFQV-------------------DAVPANGQTPIQRTIKPDVRSYT-----ITGLQPGTD 1969
            G+++                   + +  + +   Q + K    S T     +T L+    
Sbjct: 1613 GYRIYYRELEYEAGSGTEAKTLKNPIALHAELTAQSSFKTVNSSSTSTMCELTHLKKYRR 1672

Query: 1970 YKIYLYTLN---DNARSSPVVIDASTAIDA--PSNLRFLATTPNSLLVSWQPP-----RA 2019
            Y++ +   N   ++  S+PV +    A  A  P N++    T + L V+W PP       
Sbjct: 1673 YEVIMTAYNIIGESPASAPVEVFVGEAAPAMAPQNVQVTPLTASQLEVTWDPPPPESQNG 1732

Query: 2020 RITGYIIKYEKPGS----PPREVVPRPRPGVTEATITGLEPGTEYTIYVIALK---NNQK 2072
             I GY I Y +  S       +V+  P P V    +  L   T+Y + + A     +  K
Sbjct: 1733 NIQGYKIYYWEADSQNETEKMKVLFLPEPVV---RLKNLTSHTKYLVSISAFNAAGDGPK 1789

Query: 2073 SEPLIGR 2079
            S+P  GR
Sbjct: 1790 SDPQQGR 1796



 Score = 77.0 bits (188), Expect = 2e-13
 Identities = 103/475 (21%), Positives = 184/475 (38%), Gaps = 52/475 (10%)

Query: 1604 DYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISV--KWL---PSSS 1658
            DY+  + +  G     A  + I + +      P  + V+    +S +V   W+     +S
Sbjct: 644  DYSCEIVSEGGNDSRMARLEVIELPH-----SPQNLLVSPNSSHSHAVVLSWVRPFDGNS 698

Query: 1659 PVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQT 1718
            P+  Y V  +  N P        GP+ T +T+ GL P   Y   V A N  G  Q   +T
Sbjct: 699  PILYYIVELSENNSPWKVHLSNVGPEMTGVTVSGLTPARTYQFRVCAVNEVGRGQYSAET 758

Query: 1719 AVTNIDR------PKGLAFTDVDVDSIKIAWESP---------QGQVSRYRVTYSSPEDG 1763
            +   +        PK +  +     SI + W+ P         +G + RYR+    P + 
Sbjct: 759  SRLMLPEEPPSAPPKNIVASGRTNQSIMVQWQPPPETEHNGVLRGYILRYRLA-GLPGEY 817

Query: 1764 IHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHD---DMESQPLIGTQSTAIPA--PTD 1818
                  +P  E +   +  L   ++Y + V A +     + S+ +       +P   P +
Sbjct: 818  QQRNITSP--EVNYCLVTDLIIWTQYEIQVAAYNGAGLGVFSRAVTEYTLQGVPTAPPQN 875

Query: 1819 LKFTQVTPTSLSAQWTPPNVQL-----TGYRVRVTPKEKTGPMKEINLAPDSSSV---VV 1870
            ++   V  T++   W PP  Q       GY++   P +    +  + +APD   V    +
Sbjct: 876  VQTEAVNSTTIQFLWNPPPQQFINGINQGYKLLAWPADAPEAVTVVTIAPDFHGVHHGHI 935

Query: 1871 SGLMVATKYEVSVYALKDTLTSRPA--QGVVTTLENVSPPRRARVTDATETTITISWR-- 1926
            + L   T Y  SV          P+  Q V T  +          T+  +T++ +SW+  
Sbjct: 936  TNLKKFTAYFTSVLCFTTPGDGPPSTPQLVWTQEDKPGAVGHLSFTEILDTSLKVSWQEP 995

Query: 1927 -TKTETITGFQVD-AVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSS 1984
              K   ITG+Q+   V     + +  T+      Y I GL   T Y I +  +   A  +
Sbjct: 996  LEKNGIITGYQISWEVYGRNDSRLTHTLNSTTHEYKIQGLSSLTTYTIDVAAV--TAVGT 1053

Query: 1985 PVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVV 2039
             +V  ++ +   P +   L   P++L++S   PR+    +   Y+   S  R +V
Sbjct: 1054 GLVTSSTISSGVPPD---LPGAPSNLVISNISPRSATLQFRPGYDGKTSISRWIV 1105



 Score = 74.3 bits (181), Expect = 1e-12
 Identities = 143/675 (21%), Positives = 244/675 (36%), Gaps = 109/675 (16%)

Query: 662  HLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPL 721
            H  S  + GL+  V+YE Q+++  + G+             STP+     T +  P  P+
Sbjct: 1334 HTQSALLAGLRKFVLYELQVLAFTRIGN----------GVPSTPLILER-TKDDAPGPPV 1382

Query: 722  VATSESVTEITASSFVVSWVSASD---TVSGFRVEYELSEEGDEP-QYLDLPSTATSVNI 777
                    E+  +S  + W    +    + G+++ Y L+         +++ +T      
Sbjct: 1383 RLV---FPEVRLTSVRIVWQPPEEPNGIILGYQIAYRLASSSPHTFTTVEVGATVRQFTA 1439

Query: 778  PDLLPGRKYIVNVYQISEDG----EQSLILSTSQTTAPDAPPDPTVDQVDDT--SIVVRW 831
             DL P   YI  +   +  G     ++ +++T +   P  P +  V Q + T  S+ ++W
Sbjct: 1440 TDLAPESAYIFRLSAKTRQGWGEPLEATVITTEKRERPAPPRELLVPQAEVTARSLRLQW 1499

Query: 832  ---SRPQAPITGY--RIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEE- 885
               S   +PI  +  ++   P  E  +   ++   A +  +  L+P   Y + + A  + 
Sbjct: 1500 VPGSDGASPIRYFTMQVRELPRGEWQTYSSSISHEATACVVDRLRPFTSYKLRLKATNDI 1559

Query: 886  -----NQESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPP-----ESAVT 935
                 + E+  V   Q+  G P      +P        T   V I W PP        + 
Sbjct: 1560 GDSDFSSETEAVTTLQDVPGEPPGSVSATPH-------TTSSVLIQWQPPRDESLNGLLQ 1612

Query: 936  GYRVDVIPVNLPGEHGQ-----RLPI------------------SRNTFAEVTGLSPGVT 972
            GYR+    +      G      + PI                  S +T  E+T L     
Sbjct: 1613 GYRIYYRELEYEAGSGTEAKTLKNPIALHAELTAQSSFKTVNSSSTSTMCELTHLKKYRR 1672

Query: 973  Y-----YFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPP-----RA 1022
            Y      + +   S       +   +     AP N+Q    T S + V W PP       
Sbjct: 1673 YEVIMTAYNIIGESPASAPVEVFVGEAAPAMAPQNVQVTPLTASQLEVTWDPPPPESQNG 1732

Query: 1023 QITGYRLTV-GLTRRGQPRQYNV----GPSVSKYPLRNLQPASEYTVSLVAIKGNQESPK 1077
             I GY++       + +  +  V     P V    L+NL   ++Y VS+ A     + PK
Sbjct: 1733 NIQGYKIYYWEADSQNETEKMKVLFLPEPVVR---LKNLTSHTKYLVSISAFNAAGDGPK 1789

Query: 1078 A---TGVFTTLQPGSSIPPYNTEVTETTIVITW-TPAPRIGFKLGVRPSQGGEAPREVTS 1133
            +    G      PG+      +E+T TT+ ++W  PA   G   G R      AP +  S
Sbjct: 1790 SDPQQGRTHQAAPGAPSFLAFSEITSTTLNVSWGEPAAANGILQGYRVVYEPLAPVQGVS 1849

Query: 1134 DSGSIVVSG----------LTPGVEYVYTIQ--VLRDGQERDAPIVNKVVTPLSPPTNLH 1181
               ++ V G          LT GV Y + +Q   +  G E  A I        SP +   
Sbjct: 1850 KVVTVEVRGNWQRWLKVRDLTKGVTYFFRVQARTITYGPELQANITAGPAEG-SPGSPRD 1908

Query: 1182 LEANPDTGVLTVSWERSTTPD--ITGYRITTTPTNGQQGNSLEEVVHADQSSCT--FDNL 1237
            +        LT+ W    + D   TGY I   P++    +   + +    +S T   D L
Sbjct: 1909 VLVTKSASELTLQWTEGHSGDTPTTGYVIEARPSDEGLWDMFVKDIPRSATSYTLSLDKL 1968

Query: 1238 SPGLEYNVSVYTVKD 1252
              G+ Y   V  V +
Sbjct: 1969 RQGVTYEFRVVAVNE 1983



 Score = 33.5 bits (75), Expect = 2.6
 Identities = 23/82 (28%), Positives = 40/82 (48%), Gaps = 8/82 (9%)

Query: 1994 IDAPSNLRFLATTPNS-----LLVSWQPP---RARITGYIIKYEKPGSPPREVVPRPRPG 2045
            I+ P + + L  +PNS     +++SW  P    + I  YI++  +  SP +  +    P 
Sbjct: 665  IELPHSPQNLLVSPNSSHSHAVVLSWVRPFDGNSPILYYIVELSENNSPWKVHLSNVGPE 724

Query: 2046 VTEATITGLEPGTEYTIYVIAL 2067
            +T  T++GL P   Y   V A+
Sbjct: 725  MTGVTVSGLTPARTYQFRVCAV 746


>gi|222352127 sidekick 2 [Homo sapiens]
          Length = 2172

 Score =  165 bits (418), Expect = 4e-40
 Identities = 269/1145 (23%), Positives = 439/1145 (38%), Gaps = 173/1145 (15%)

Query: 1043 NVGPSVSKYPLRNLQPASEYTVSLVAIK--GNQESPKATGVFTTLQPGSSIPPYNTEV-- 1098
            +V P  +   ++ L PA  Y   L A+   G  +  K T   +  +   + PP N     
Sbjct: 642  SVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSLPEEPPTAPPQNVIASG 701

Query: 1099 -TETTIVITWTPAPR-----------IGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPG 1146
             T  +I+I W P P            I + L   P  G +      +D  ++++  L   
Sbjct: 702  RTNQSIMIQWQPPPESHQNGILKGYIIRYCLAGLPV-GYQFKNITDADVNNLLLEDLIIW 760

Query: 1147 VEYVYTIQVLRDGQERDAPIVNKVV------TPLSPPTNLHLEANPDT------------ 1188
              Y   I+V            +KV        P  PP N+H EA   T            
Sbjct: 761  TNY--EIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNVHAEATNSTTIRFTWNAPSPQ 818

Query: 1189 -------GVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGL 1241
                   G   ++WE     ++T   +T  P       + ++ +H    S     L    
Sbjct: 819  FINGINQGYKLIAWEPEQEEEVT--MVTARP-------NFQDSIHVGFVS----GLKKFT 865

Query: 1242 EYNVSVY---TVKDDKESVPISDTIIPEVP-QLTDLSFVDITDSSIGLRWTPLNSST--I 1295
            EY  SV    T  D   S P       +VP  +  LSF +I D+S+ + W         +
Sbjct: 866  EYFTSVLCFTTPGDGPRSTPQLVRTHEDVPGPVGHLSFSEILDTSLKVSWQEPGEKNGIL 925

Query: 1296 IGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQ 1355
             GYRI+             ++ +    Y VTGL     Y I V  + + G+   +  T  
Sbjct: 926  TGYRISWEEYNRTNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQVSASTIS 985

Query: 1356 TAVPP-----PTDLRFTNIGPDTMRVTWAP--PPSIDLTNFLV--RYSPVKNEED---VA 1403
            + VPP     PT+L  +NIGP ++ + + P       ++ +LV  +   V   E+   + 
Sbjct: 986  SGVPPELPGPPTNLGISNIGPRSVTLQFRPGYDGKTSISRWLVEAQVGVVGEGEEWLLIH 1045

Query: 1404 ELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGL------DSPTGIDF 1457
            +LS  P   ++ + +L P T Y   +  V     S P +  +K          +P  +  
Sbjct: 1046 QLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQPSRKIQTLQAPPDMAPANVSL 1105

Query: 1458 SDITANSFTVHWIA-------PRATITGYRIRHHPEHFSGRPR----EDRVPHSRNSITL 1506
               +  S  + W+              GY+I++      G+      +DRV       T+
Sbjct: 1106 RTASETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDRV---ERDYTI 1162

Query: 1507 TNLTPGTEYVVSIVALNGREESP---LLIGQ--QSTVSDVPRDLEVVAATPTSLLISW-D 1560
             +L   TEY V + A N     P    ++G+  +S  S  P ++  +A T +S+L+ W +
Sbjct: 1163 EDLEEWTEYRVQVQAFNAIGSGPWSQTVVGRTRESVPSSGPTNVSALATTSSSMLVRWSE 1222

Query: 1561 APAVT----VRYYRITYGETGGNSPVQEFTVPGSKS-TATISGLKPGVDYTITVYAVTGR 1615
             P       V  Y++ Y E   ++  + + V G+ S +A ++GL   V Y + V A T  
Sbjct: 1223 VPEADRNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSRSAQLTGLGKYVLYEVQVLAFTRI 1282

Query: 1616 GDSPASSKPISINYRTEIDKPSQ-MQVTDVQDNSISVKWLPSSSP---VTGYRVTTTPKN 1671
            GD   S  PI      ++  P   +   +V+  S+ + W P ++P   +  Y++T     
Sbjct: 1283 GDGSPSHPPILERTLDDVPGPPMGILFPEVRTTSVRLIWQPPAAPNGIILAYQITHRLNT 1342

Query: 1672 GPGPTKT-KTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNI--DRPKG 1728
                T T +   P   + T  GL+P   Y+  + AQ   G  +      VT    DRP+ 
Sbjct: 1343 TTANTATVEVLAPSARQYTATGLKPESVYLFRITAQTRKGWGEAAEALVVTTEKRDRPQP 1402

Query: 1729 -----LAFTDVDVDSIKIAWESPQGQVSR---YRVTYSSPEDGIHELFPAPDGEEDTAEL 1780
                 +   DV   S+ ++WE     +S    Y +       G   L  A      ++ +
Sbjct: 1403 PSRPMVQQEDVRARSVLLSWEPGSDGLSPVRYYTIQTRELPSGRWALHSASVSHNASSFI 1462

Query: 1781 -QGLRPGSEYTVSVVALHD------DMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQW 1833
               L+P + Y   V A +D        ES+ L   Q+    APT L  T  T TS+  +W
Sbjct: 1463 VDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTILSVTPHTTTSVLIRW 1522

Query: 1834 TPP-----NVQLTGYRVR---------------------VTPKEKTGPMKEINLA-PDSS 1866
             PP     N  L G+R+R                      T  E T      NL+ P  +
Sbjct: 1523 QPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGINNPGATWAELTSMYSMRNLSRPSLT 1582

Query: 1867 SVVVSGLMVATKYEV--SVY-ALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITI 1923
               +  L    +YE+  SVY A+ +  +S P +  V      + PR   V  AT T + +
Sbjct: 1583 QYELDNLNKHRRYEIRMSVYNAVGEGPSSPPQEVFVGEAVPTAAPRNVVVHGATATQLDV 1642

Query: 1924 SWR-----TKTETITGFQVDAVPANGQTPIQR--TIKPDVRSYTITGLQPGTDYKIYLYT 1976
            +W      ++   I G+++    A      +R  T+     S  +  L   T Y + +  
Sbjct: 1643 TWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLFLAENSVKLKNLTGYTAYMVSVAA 1702

Query: 1977 LN---DNARSSPVVIDASTAI-DAPSNLRFLATTPNSLLVSWQPPR---ARITGYIIKYE 2029
             N   D  RS+P       A   APS+++F   T  S+ VSW+ P+     + GY + YE
Sbjct: 1703 FNAAGDGPRSTPTQGQTQQAAPSAPSSVKFSELTTTSVNVSWEAPQFPNGILEGYRLVYE 1762

Query: 2030 KPGSP 2034
             P SP
Sbjct: 1763 -PCSP 1766



 Score =  144 bits (362), Expect = 1e-33
 Identities = 300/1357 (22%), Positives = 493/1357 (36%), Gaps = 181/1357 (13%)

Query: 793  ISEDGEQSLILSTSQTTAPDAPPDP--TVDQVDDTSIVVRWSRP---QAPITGYRIVYSP 847
            IS  G  S          P AP  P  T+  V+  +I + W++P    +P+  Y +  S 
Sbjct: 572  ISAGGNDSRSAHLRVRQLPHAPEHPVATLSTVERRAINLTWTKPFDGNSPLIRYILEMSE 631

Query: 848  SVEGSSTEL-NLPETANSVTLSDLQPGVQYNITIYAVEE------NQESTPVVIQQETTG 900
            +    +  L ++   A SVT+  L P   Y   + AV +      ++++  V + +E   
Sbjct: 632  NNAPWTVLLASVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSLPEEPPT 691

Query: 901  TPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESA-----VTGYRVDVIPVNLP-GEHGQRL 954
             P  + + S R       T+  + I W PP  +     + GY +      LP G   + +
Sbjct: 692  APPQNVIASGR-------TNQSIMIQWQPPPESHQNGILKGYIIRYCLAGLPVGYQFKNI 744

Query: 955  PISRNTFAEVTGLSPGVTYYFKVFAVSH---GRESKPLT--AQQTTKLDAPTNLQFVNET 1009
              +      +  L     Y  +V A +    G  S  +T    Q      P N+      
Sbjct: 745  TDADVNNLLLEDLIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNVHAEATN 804

Query: 1010 DSTVLVRWTPPRAQIT-----GYRLTVGLTRRGQPRQYNVGPSVSKYP----------LR 1054
             +T+   W  P  Q       GY+L        +P Q      V+  P          + 
Sbjct: 805  STTIRFTWNAPSPQFINGINQGYKLIAW-----EPEQEEEVTMVTARPNFQDSIHVGFVS 859

Query: 1055 NLQPASEYTVSLVAIKGNQESPKATGVFTTLQ---PGSSIPPYNTEVTETTIVITWT-PA 1110
             L+  +EY  S++      + P++T          PG       +E+ +T++ ++W  P 
Sbjct: 860  GLKKFTEYFTSVLCFTTPGDGPRSTPQLVRTHEDVPGPVGHLSFSEILDTSLKVSWQEPG 919

Query: 1111 PRIGFKLGVRPS--QGGEAPREVTSDSGSIV----VSGLTPGVEYVYTIQVLRD---GQE 1161
             + G   G R S  +       VT    ++     V+GLT    Y   +  +     GQ 
Sbjct: 920  EKNGILTGYRISWEEYNRTNTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQV 979

Query: 1162 RDAPIVNKVVTPL-SPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNS 1220
              + I + V   L  PPTNL + +N     +T+ +        +  R       G  G  
Sbjct: 980  SASTISSGVPPELPGPPTNLGI-SNIGPRSVTLQFRPGYDGKTSISRWLVEAQVGVVGEG 1038

Query: 1221 LEEVV------HADQSSCTFDNLSPGLEYNVSVYTVKDDKESVP------ISDTIIPEVP 1268
             E ++        D  S    +L+P   Y+  +  V     S P      I     P   
Sbjct: 1039 EEWLLIHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQPSRKIQTLQAPPDM 1098

Query: 1269 QLTDLSFVDITDSSIGLRWTPL------NSSTIIGYRITVVAA-GEGIPIFEDFVDSSVG 1321
               ++S    +++S+ LRW PL       +   +GY+I    + G G  +     D    
Sbjct: 1099 APANVSLRTASETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDRVER 1158

Query: 1322 YYTVTGLEPGIDYDISV--ITLINGGESAPTTLTQQTAVPP---PTDLRFTNIGPDTMRV 1376
             YT+  LE   +Y + V     I  G  + T + +     P   PT++        +M V
Sbjct: 1159 DYTIEDLEEWTEYRVQVQAFNAIGSGPWSQTVVGRTRESVPSSGPTNVSALATTSSSMLV 1218

Query: 1377 TWAPPPSIDLTNFLVRYSPVKNEEDVAE-----LSISPSDNAVVLTNLLPGTEYVVSVSS 1431
             W+  P  D    ++ Y  +  E+D        L    S  +  LT L     Y V V +
Sbjct: 1219 RWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSRSAQLTGLGKYVLYEVQVLA 1278

Query: 1432 VYEQHESTPLRGR--QKTGLD---SPTGIDFSDITANSFTVHW---IAPRATITGYRIRH 1483
                 + +P      ++T  D    P GI F ++   S  + W    AP   I  Y+I H
Sbjct: 1279 FTRIGDGSPSHPPILERTLDDVPGPPMGILFPEVRTTSVRLIWQPPAAPNGIILAYQITH 1338

Query: 1484 HPEHFSGRPREDRV-PHSRNSITLTNLTPGTEYVVSIVALN----GREESPLLIGQQSTV 1538
                 +       V   S    T T L P + Y+  I A      G     L++  +   
Sbjct: 1339 RLNTTTANTATVEVLAPSARQYTATGLKPESVYLFRITAQTRKGWGEAAEALVVTTEKRD 1398

Query: 1539 SDVPRDLEVVAATPT---SLLISWDAPA---VTVRYYRITYGET-GGNSPVQEFTVPGSK 1591
               P    +V        S+L+SW+  +     VRYY I   E   G   +   +V  + 
Sbjct: 1399 RPQPPSRPMVQQEDVRARSVLLSWEPGSDGLSPVRYYTIQTRELPSGRWALHSASVSHNA 1458

Query: 1592 STATISGLKPGVDYTITVYAVTGRGDSPASSKPISIN--YRTEIDKPSQMQVTDVQDNSI 1649
            S+  +  LKP   Y   V A    GDS  S +  S+        + P+ + VT     S+
Sbjct: 1459 SSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTILSVTPHTTTSV 1518

Query: 1650 SVKWLPSSSP-----VTGYRV-------------TTTPKNGPGPTKTKTAG--------- 1682
             ++W P +       + G+R+             T    N PG T  +            
Sbjct: 1519 LIRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGINNPGATWAELTSMYSMRNLSR 1578

Query: 1683 PDQTEMTIEGLQPTVEYVV--SVY---AQNPSGESQPLVQTAVTNIDRPKGLAFTDVDVD 1737
            P  T+  ++ L     Y +  SVY    + PS   Q +          P+ +        
Sbjct: 1579 PSLTQYELDNLNKHRRYEIRMSVYNAVGEGPSSPPQEVFVGEAVPTAAPRNVVVHGATAT 1638

Query: 1738 SIKIAWESP-----QGQVSRYRVTYSSPEDG-----IHELFPAPDGEEDTAELQGLRPGS 1787
             + + WE P      G +  Y++ +   + G     +  LF A    E++ +L+ L   +
Sbjct: 1639 QLDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVKTLFLA----ENSVKLKNLTGYT 1694

Query: 1788 EYTVSVVALH---DDMESQPLIG-TQSTAIPAPTDLKFTQVTPTSLSAQWTP---PNVQL 1840
             Y VSV A +   D   S P  G TQ  A  AP+ +KF+++T TS++  W     PN  L
Sbjct: 1695 AYMVSVAAFNAAGDGPRSTPTQGQTQQAAPSAPSSVKFSELTTTSVNVSWEAPQFPNGIL 1754

Query: 1841 TGYRVRVTP-KEKTGPMKEINLAPDSSS---VVVSGLMVATKYEVSVYALKDTLTSRPAQ 1896
             GYR+   P     G  K + +    +S   + V  L     Y   + A   T       
Sbjct: 1755 EGYRLVYEPCSPVDGVSKIVTVDVKGNSPLWLKVKDLAEGVTYRFRIRAKTFTYGPEIEA 1814

Query: 1897 GVVTTLENVSP-PRRARVTDATETTITISWRTKTE---TITGFQVDAVPAN-GQTPIQ-R 1950
             V T     +P P    +     + I I W +       IT + ++A P++ G   I  +
Sbjct: 1815 NVTTGPGEGAPGPPGVPIIVRYSSAIAIHWSSGDPGKGPITRYVIEARPSDEGLWDILIK 1874

Query: 1951 TIKPDVRSYTITG--LQPGTDYKIYLYTLNDNARSSP 1985
             I  +V SYT +   L+PG  Y   +  +ND    +P
Sbjct: 1875 DIPKEVSSYTFSMDILKPGVSYDFRVIAVNDYGFGTP 1911



 Score =  140 bits (354), Expect = 1e-32
 Identities = 292/1388 (21%), Positives = 523/1388 (37%), Gaps = 197/1388 (14%)

Query: 594  IGEWHCQPLQTYPSSSGPVEVFITETPSQPNSHPIQ-------------WNAPQP--SHI 638
            IG + C+ +    + S    + + + P  P  HP+              W  P    S +
Sbjct: 564  IGTYTCRVISAGGNDSRSAHLRVRQLPHAPE-HPVATLSTVERRAINLTWTKPFDGNSPL 622

Query: 639  SKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFT 698
             +YIL     N+      A++     S T+KGL P   Y+ +L ++   G  +   F   
Sbjct: 623  IRYILEMSENNAPWTVLLASVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQ---FSKD 679

Query: 699  TTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDT-----VSGFRVE 753
            T   S P         T P   ++A+       T  S ++ W    ++     + G+ + 
Sbjct: 680  TERVSLPEEP-----PTAPPQNVIASGR-----TNQSIMIQWQPPPESHQNGILKGYIIR 729

Query: 754  YELSEEGDEPQYLDL-PSTATSVNIPDLLPGRKYIVNVYQISEDG---EQSLILSTSQTT 809
            Y L+      Q+ ++  +   ++ + DL+    Y + V   +  G     S +   +   
Sbjct: 730  YCLAGLPVGYQFKNITDADVNNLLLEDLIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQG 789

Query: 810  APDAPP-DPTVDQVDDTSIVVRWSRPQAPI-----TGYRIV-YSPSVEGSSTEL----NL 858
             P  PP +   +  + T+I   W+ P          GY+++ + P  E   T +    N 
Sbjct: 790  VPTVPPGNVHAEATNSTTIRFTWNAPSPQFINGINQGYKLIAWEPEQEEEVTMVTARPNF 849

Query: 859  PETANSVTLSDLQPGVQYNITIYAVE---ENQESTPVVIQQETTGTPRSDTVPSP-RDLQ 914
             ++ +   +S L+   +Y  ++       +   STP +++         + VP P   L 
Sbjct: 850  QDSIHVGFVSGLKKFTEYFTSVLCFTTPGDGPRSTPQLVRTH-------EDVPGPVGHLS 902

Query: 915  FVEVTDVKVTIMWTPP---ESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGV 971
            F E+ D  + + W  P      +TGYR+     N           +      VTGL+   
Sbjct: 903  FSEILDTSLKVSWQEPGEKNGILTGYRISWEEYNRTNTRVTHYLPNVTLEYRVTGLTALT 962

Query: 972  TYYFKVFAVSHGRESKPLTAQQTTKL-----DAPTNLQFVNETDSTVLVRWTP---PRAQ 1023
            TY  +V A++   + +   +  ++ +       PTNL   N    +V +++ P    +  
Sbjct: 963  TYTIEVAAMTSKGQGQVSASTISSGVPPELPGPPTNLGISNIGPRSVTLQFRPGYDGKTS 1022

Query: 1024 ITGY--RLTVGLTRRGQP----RQYNVGPSVSKYPLRNLQPASEYTVSL--VAIKGNQES 1075
            I+ +     VG+   G+      Q +  P      + +L P + Y+  +  V I G    
Sbjct: 1023 ISRWLVEAQVGVVGEGEEWLLIHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVGTSPP 1082

Query: 1076 PKATGVFTTLQPGSSIPPYNTEV---TETTIVITWTPAPR---------IGFKLGVRPSQ 1123
             + +    TLQ    + P N  +   +ET++ + W P P          +G+K+    S 
Sbjct: 1083 SQPSRKIQTLQAPPDMAPANVSLRTASETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSD 1142

Query: 1124 G-GEAPREVTSD--SGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVV------TPL 1174
            G G+    V  D       +  L    E  Y +QV         P    VV       P 
Sbjct: 1143 GHGKTLSHVVQDRVERDYTIEDLEEWTE--YRVQVQAFNAIGSGPWSQTVVGRTRESVPS 1200

Query: 1175 SPPTNLHLEANPDTGVLTVSWERSTTPD----ITGYRITTTPTNGQQGNSLEEVVHADQS 1230
            S PTN+   A   + +L V W      D    + GY++     +         V      
Sbjct: 1201 SGPTNVSALATTSSSML-VRWSEVPEADRNGLVLGYKVMYKEKDSDTQPRFWLVEGNSSR 1259

Query: 1231 SCTFDNLSPGLEYNVSVYT---VKDDKES-VPISDTIIPEVP-QLTDLSFVDITDSSIGL 1285
            S     L   + Y V V     + D   S  PI +  + +VP     + F ++  +S+ L
Sbjct: 1260 SAQLTGLGKYVLYEVQVLAFTRIGDGSPSHPPILERTLDDVPGPPMGILFPEVRTTSVRL 1319

Query: 1286 RWTP--LNSSTIIGYRIT-VVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDY--DISVIT 1340
             W P    +  I+ Y+IT  +          + +  S   YT TGL+P   Y   I+  T
Sbjct: 1320 IWQPPAAPNGIILAYQITHRLNTTTANTATVEVLAPSARQYTATGLKPESVYLFRITAQT 1379

Query: 1341 LINGGESAP----TTLTQQTAVPPPTDL-RFTNIGPDTMRVTWAPPPSIDLTNFLVRYSP 1395
                GE+A     TT  +    PP   + +  ++   ++ ++W  P S  L+   VRY  
Sbjct: 1380 RKGWGEAAEALVVTTEKRDRPQPPSRPMVQQEDVRARSVLLSW-EPGSDGLSP--VRYYT 1436

Query: 1396 VKNEE------DVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYE------QHESTPLRG 1443
            ++  E       +   S+S + ++ ++  L P T Y   V +  +        ES  L  
Sbjct: 1437 IQTRELPSGRWALHSASVSHNASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTT 1496

Query: 1444 RQKTGLDSPTGIDFSDITANSFTVHWIAP-----RATITGYRIRHHPEHFSG----RPRE 1494
             Q    ++PT +  +  T  S  + W  P        + G+RIR+    + G      R 
Sbjct: 1497 LQAAPDEAPTILSVTPHTTTSVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRG 1556

Query: 1495 DRVPH---------------SRNSIT---LTNLTPGTEYVVSIVALNGREESPLLIGQQS 1536
               P                SR S+T   L NL     Y + +   N   E P    Q+ 
Sbjct: 1557 INNPGATWAELTSMYSMRNLSRPSLTQYELDNLNKHRRYEIRMSVYNAVGEGPSSPPQEV 1616

Query: 1537 TVSD-----VPRDLEVVAATPTSLLISWDAPAV-----TVRYYRITYGET-GGNSPVQEF 1585
             V +      PR++ V  AT T L ++W+ P +      ++ Y+I + E   GN   +  
Sbjct: 1617 FVGEAVPTAAPRNVVVHGATATQLDVTWEPPPLDSQNGDIQGYKIYFWEAQRGNLTERVK 1676

Query: 1586 TVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQ 1645
            T+  ++++  +  L     Y ++V A    GD P S+       +     PS ++ +++ 
Sbjct: 1677 TLFLAENSVKLKNLTGYTAYMVSVAAFNAAGDGPRSTPTQGQTQQAAPSAPSSVKFSELT 1736

Query: 1646 DNSISVKWLPSSSP---VTGYRVTTTPKNG-PGPTKTKTA---GPDQTEMTIEGLQPTVE 1698
              S++V W     P   + GYR+   P +   G +K  T    G     + ++ L   V 
Sbjct: 1737 TTSVNVSWEAPQFPNGILEGYRLVYEPCSPVDGVSKIVTVDVKGNSPLWLKVKDLAEGVT 1796

Query: 1699 YVVSVYAQNPSGESQPLVQTAVT-----NIDRPKGLAFTDVDVDSIKIAWES---PQGQV 1750
            Y   + A+  +    P ++  VT         P G+        +I I W S    +G +
Sbjct: 1797 YRFRIRAK--TFTYGPEIEANVTTGPGEGAPGPPGVPIIVRYSSAIAIHWSSGDPGKGPI 1854

Query: 1751 SRYRVTYSSPEDGIHELFPAPDGEE---DTAELQGLRPGSEYTVSVVALHDDMESQPLIG 1807
            +RY +     ++G+ ++      +E    T  +  L+PG  Y   V+A++D     P   
Sbjct: 1855 TRYVIEARPSDEGLWDILIKDIPKEVSSYTFSMDILKPGVSYDFRVIAVNDYGFGTP--S 1912

Query: 1808 TQSTAIPA 1815
            + S ++PA
Sbjct: 1913 SPSQSVPA 1920



 Score = 72.8 bits (177), Expect = 4e-12
 Identities = 92/382 (24%), Positives = 153/382 (40%), Gaps = 47/382 (12%)

Query: 1734 VDVDSIKIAWESP---QGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYT 1790
            V+  +I + W  P      + RY +  S        L  + D +  +  ++GL P   Y 
Sbjct: 603  VERRAINLTWTKPFDGNSPLIRYILEMSENNAPWTVLLASVDPKATSVTVKGLVPARSYQ 662

Query: 1791 VSVVALHDDMESQPLIGTQSTAIPA------PTDLKFTQVTPTSLSAQWTPP-----NVQ 1839
              + A++D  + Q    T+  ++P       P ++  +  T  S+  QW PP     N  
Sbjct: 663  FRLCAVNDVGKGQFSKDTERVSLPEEPPTAPPQNVIASGRTNQSIMIQWQPPPESHQNGI 722

Query: 1840 LTGYRVRVTPKEKTGPMKEINLAP-DSSSVVVSGLMVATKYEVSVYALKDT--------L 1890
            L GY +R          +  N+   D +++++  L++ T YE+ V A            +
Sbjct: 723  LKGYIIRYCLAGLPVGYQFKNITDADVNNLLLEDLIIWTNYEIEVAAYNSAGLGVYSSKV 782

Query: 1891 TSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTETIT-----GFQVDA-VPANG 1944
            T    QGV T      PP          TTI  +W   +         G+++ A  P   
Sbjct: 783  TEWTLQGVPTV-----PPGNVHAEATNSTTIRFTWNAPSPQFINGINQGYKLIAWEPEQE 837

Query: 1945 QTPIQRTIKPDVRSYT----ITGLQPGTDY---KIYLYTLNDNARSSPVVIDASTAIDAP 1997
            +     T +P+ +       ++GL+  T+Y    +   T  D  RS+P ++     +  P
Sbjct: 838  EEVTMVTARPNFQDSIHVGFVSGLKKFTEYFTSVLCFTTPGDGPRSTPQLVRTHEDVPGP 897

Query: 1998 -SNLRFLATTPNSLLVSWQPPRAR---ITGYIIKYEKPGSPPREVVPRPRPGVT-EATIT 2052
              +L F      SL VSWQ P  +   +TGY I +E+       V     P VT E  +T
Sbjct: 898  VGHLSFSEILDTSLKVSWQEPGEKNGILTGYRISWEEYNRTNTRVT-HYLPNVTLEYRVT 956

Query: 2053 GLEPGTEYTIYVIALKNNQKSE 2074
            GL   T YTI V A+ +  + +
Sbjct: 957  GLTALTTYTIEVAAMTSKGQGQ 978



 Score = 70.9 bits (172), Expect = 1e-11
 Identities = 111/557 (19%), Positives = 213/557 (38%), Gaps = 47/557 (8%)

Query: 1504 ITLTNLTPGTEYVVSIVALNGREESP--LLIGQQSTVSDVPRDLEVVAATPTSLL--ISW 1559
            I+ T+++    Y        G +E+   L++  ++ ++  P+D  V+  T  S++  ++ 
Sbjct: 462  ISPTHISDAGTYTCLATNSRGVDEASADLVVWARTRITKPPQDQSVIKGTQASMVCGVTH 521

Query: 1560 DAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSP 1619
            D P VT+RY     G T G        +  + S   IS    G   T T   ++  G+  
Sbjct: 522  D-PRVTIRYIWEKDGATLGTESHPRIRLDRNGSLH-ISQTWSGDIGTYTCRVISAGGNDS 579

Query: 1620 ASSKPISINYRTEIDKPSQMQVTDVQDNSISVKW---LPSSSPVTGYRVTTTPKNGPGPT 1676
             S+  + +       +     ++ V+  +I++ W      +SP+  Y +  +  N P   
Sbjct: 580  RSAH-LRVRQLPHAPEHPVATLSTVERRAINLTWTKPFDGNSPLIRYILEMSENNAPWTV 638

Query: 1677 KTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDR------PKGLA 1730
               +  P  T +T++GL P   Y   + A N  G+ Q    T   ++        P+ + 
Sbjct: 639  LLASVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSLPEEPPTAPPQNVI 698

Query: 1731 FTDVDVDSIKIAWESP-----QGQVSRYRVTYSSPEDGI-HELFPAPDGEEDTAELQGLR 1784
             +     SI I W+ P      G +  Y + Y      + ++     D + +   L+ L 
Sbjct: 699  ASGRTNQSIMIQWQPPPESHQNGILKGYIIRYCLAGLPVGYQFKNITDADVNNLLLEDLI 758

Query: 1785 PGSEYTVSVVALHD---DMESQPLIGTQSTAIPA--PTDLKFTQVTPTSLSAQWTPPNVQ 1839
              + Y + V A +     + S  +       +P   P ++       T++   W  P+ Q
Sbjct: 759  IWTNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNVHAEATNSTTIRFTWNAPSPQ 818

Query: 1840 L-----TGYRVRVTPKEKTGPMKEINLAPDSSSVV----VSGLMVATKYEVSVYALKDTL 1890
                   GY++     E+   +  +   P+    +    VSGL   T+Y  SV       
Sbjct: 819  FINGINQGYKLIAWEPEQEEEVTMVTARPNFQDSIHVGFVSGLKKFTEYFTSVLCFTTPG 878

Query: 1891 TS-RPAQGVVTTLENV-SPPRRARVTDATETTITISWR---TKTETITGFQVDAVPANGQ 1945
               R    +V T E+V  P      ++  +T++ +SW+    K   +TG+++     N  
Sbjct: 879  DGPRSTPQLVRTHEDVPGPVGHLSFSEILDTSLKVSWQEPGEKNGILTGYRISWEEYNRT 938

Query: 1946 TPIQRTIKPDVR-SYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAI-----DAPSN 1999
                    P+V   Y +TGL   T Y I +  +    +        S+ +       P+N
Sbjct: 939  NTRVTHYLPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQVSASTISSGVPPELPGPPTN 998

Query: 2000 LRFLATTPNSLLVSWQP 2016
            L      P S+ + ++P
Sbjct: 999  LGISNIGPRSVTLQFRP 1015


>gi|109633039 protein tyrosine phosphatase, receptor type, F isoform 2
            precursor [Homo sapiens]
          Length = 1898

 Score =  153 bits (387), Expect = 2e-36
 Identities = 172/631 (27%), Positives = 264/631 (41%), Gaps = 71/631 (11%)

Query: 1493 REDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPR---DLEVVA 1549
            +ED +P  RN + L+N+     Y    ++  G  E+      Q TV  +P+   DL V  
Sbjct: 274  KEDEMPVGRNVLELSNVVRSANYTCVAISSLGMIEATA----QVTVKALPKPPIDLVVTE 329

Query: 1550 ATPTSLLISWDAP-AVTVRYYRITYGETGGNSPVQEFTVPGSKSTA-TISGLKPGVDYTI 1607
             T TS+ ++WD+  +  V YY I Y   G   P QE  V G  +T  +I GL P  +Y  
Sbjct: 330  TTATSVTLTWDSGNSEPVTYYGIQYRAAGTEGPFQE--VDGVATTRYSIGGLSPFSEYAF 387

Query: 1608 TVYAVTGRGDSPASSKPISINYRTEIDKPS----QMQVTDVQDNSISVKWLPSSSP---V 1660
             V AV   G  P S    ++  RT    PS    ++Q   +  +++ V+W P   P   V
Sbjct: 388  RVLAVNSIGRGPPSE---AVRARTGEQAPSSPPRRVQARMLSASTMLVQWEPPEEPNGLV 444

Query: 1661 TGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEG-LQPTVEYVVSVYAQNPSGESQPLVQTA 1719
             GYRV  TP +   P        D   +T  G L P + Y + V A    G+  P     
Sbjct: 445  RGYRVYYTPDSRRPPNAWHKHNTDAGLLTTVGSLLPGITYSLRVLAFTAVGDGPPSPTIQ 504

Query: 1720 V-TNIDRPKGLAFTDVDVDS---IKIAWE-SPQGQVSRYRVTY--SSPEDGIHELFPAPD 1772
            V T    P   A    +V+S   I+++W   PQ ++  Y + Y  +  ED  H++   P 
Sbjct: 505  VKTQQGVPAQPADFQAEVESDTRIQLSWLLPPQERIIMYELVYWAAEDEDQQHKVTFDPT 564

Query: 1773 GEEDTAELQGLRPGSEYTVSVVALHD--------DMESQPLIGTQSTAIPAPTDLKFTQV 1824
                +  L+ L+P + Y   + A  D         +E++     QST    P  +    +
Sbjct: 565  S---SYTLEDLKPDTLYRFQLAARSDMGVGVFTPTIEART---AQSTPSAPPQKVMCVSM 618

Query: 1825 TPTSLSAQWTPP-----NVQLTGYRV--RVTPKEKTGPMKEINLAPDSSSVVVSGLMVAT 1877
              T++   W PP     N  +T Y V       E  G      ++ + SS  + GL   T
Sbjct: 619  GSTTVRVSWVPPPADSRNGVITQYSVAYEAVDGEDRGRHVVDGISREHSSWDLVGLEKWT 678

Query: 1878 KYEVSVYALKDTLTSRPAQGV-VTTLENV--SPPRRARVTDATETTITISWRTKTET--- 1931
            +Y V V A  D      +  V V T E+V   PPR+  V     T + + W+    +   
Sbjct: 679  EYRVWVRAHTDVGPGPESSPVLVRTDEDVPSGPPRKVEVEPLNSTAVHVYWKLPVPSKQH 738

Query: 1932 --ITGFQVDAVPANGQTP-----IQRTIKPDVRSYTITGLQPGTDYKIYLY---TLNDNA 1981
              I G+QV  V      P     IQ  +  + +  TI+GL P T Y + +    T  D A
Sbjct: 739  GQIRGYQVTYVRLENGEPRGLPIIQDVMLAEAQETTISGLTPETTYSVTVAAYTTKGDGA 798

Query: 1982 RSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPR---ARITGYIIKYEKPGSPPREV 2038
            RS P ++  + A+     +    T  N+ L+ W PP+     + GY ++Y +        
Sbjct: 799  RSKPKIVTTTGAVPGRPTMMISTTAMNTALLQWHPPKELPGELLGYRLQYCRADEARPNT 858

Query: 2039 VPRPRPGVTEATITGLEPGTEYTIYVIALKN 2069
            +   +      T+TGL  GT Y I+ +A KN
Sbjct: 859  IDFGKDD-QHFTVTGLHKGTTY-IFRLAAKN 887



 Score =  142 bits (358), Expect = 4e-33
 Identities = 167/728 (22%), Positives = 287/728 (39%), Gaps = 68/728 (9%)

Query: 1348 APTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSI 1407
            A   +T +    PP DL  T     ++ +TW    S  +T + ++Y     E    E+  
Sbjct: 309  ATAQVTVKALPKPPIDLVVTETTATSVTLTWDSGNSEPVTYYGIQYRAAGTEGPFQEVD- 367

Query: 1408 SPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRG-RQKTGLDSPTG----IDFSDITA 1462
              +     +  L P +EY   V +V       P    R +TG  +P+     +    ++A
Sbjct: 368  GVATTRYSIGGLSPFSEYAFRVLAVNSIGRGPPSEAVRARTGEQAPSSPPRRVQARMLSA 427

Query: 1463 NSFTVHWIAPR---ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLT---NLTPGTEYV 1516
            ++  V W  P      + GYR+ + P+  S RP      H+ ++  LT   +L PG  Y 
Sbjct: 428  STMLVQWEPPEEPNGLVRGYRVYYTPD--SRRPPNAWHKHNTDAGLLTTVGSLLPGITYS 485

Query: 1517 VSIVALNGREESP----LLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVT-VRYYRI 1571
            + ++A     + P    + +  Q  V   P D +    + T + +SW  P    +  Y +
Sbjct: 486  LRVLAFTAVGDGPPSPTIQVKTQQGVPAQPADFQAEVESDTRIQLSWLLPPQERIIMYEL 545

Query: 1572 TYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRT 1631
             Y          + T   + S+ T+  LKP   Y    + +  R D        +I  RT
Sbjct: 546  VYWAAEDEDQQHKVTFDPT-SSYTLEDLKPDTLYR---FQLAARSDMGVGVFTPTIEART 601

Query: 1632 EIDKPS----QMQVTDVQDNSISVKWLPSSSP-----VTGYRVTTTPKNGPGPTKTKTAG 1682
                PS    ++    +   ++ V W+P  +      +T Y V     +G    +    G
Sbjct: 602  AQSTPSAPPQKVMCVSMGSTTVRVSWVPPPADSRNGVITQYSVAYEAVDGEDRGRHVVDG 661

Query: 1683 --PDQTEMTIEGLQPTVEYVVSVYAQN---PSGESQPLVQTAVTNIDR--PKGLAFTDVD 1735
               + +   + GL+   EY V V A     P  ES P++     ++    P+ +    ++
Sbjct: 662  ISREHSSWDLVGLEKWTEYRVWVRAHTDVGPGPESSPVLVRTDEDVPSGPPRKVEVEPLN 721

Query: 1736 VDSIKIAWESP-----QGQVSRYRVTYSSPEDGIHELFPAPD----GEEDTAELQGLRPG 1786
              ++ + W+ P      GQ+  Y+VTY   E+G     P        E     + GL P 
Sbjct: 722  STAVHVYWKLPVPSKQHGQIRGYQVTYVRLENGEPRGLPIIQDVMLAEAQETTISGLTPE 781

Query: 1787 SEYTVSVVALH---DDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNV---QL 1840
            + Y+V+V A     D   S+P I T + A+P    +  +     +   QW PP     +L
Sbjct: 782  TTYSVTVAAYTTKGDGARSKPKIVTTTGAVPGRPTMMISTTAMNTALLQWHPPKELPGEL 841

Query: 1841 TGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVT 1900
             GYR++    ++  P   I+   D     V+GL   T Y   + A          +  + 
Sbjct: 842  LGYRLQYCRADEARP-NTIDFGKDDQHFTVTGLHKGTTYIFRLAAKNRAGLGEEFEKEIR 900

Query: 1901 TLENVSP--PRRARVTDATETTITISW-----RTKTETITGFQVDAVPANGQTPIQRTIK 1953
            T E++    P+   VT  T +T  ++W       +   I  + V     N Q  +Q  I 
Sbjct: 901  TPEDLPSGFPQNLHVTGLTTSTTELAWDPPVLAERNGRIISYTVVFRDINSQQELQN-IT 959

Query: 1954 PDVRSYTITGLQPGTDY--KIYLYTLNDNARSSPVVIDASTAIDA--PSNLRFLATTPNS 2009
             D R +T+TGL+P T Y  K+  +T   +   SP +   +  ++     N R  A    S
Sbjct: 960  TDTR-FTLTGLKPDTTYDIKVRAWTSKGSGPLSPSIQSRTMPVEQVFAKNFRVAAAMKTS 1018

Query: 2010 LLVSWQPP 2017
            +L+SW+ P
Sbjct: 1019 VLLSWEVP 1026



 Score =  130 bits (328), Expect = 1e-29
 Identities = 177/732 (24%), Positives = 297/732 (40%), Gaps = 84/732 (11%)

Query: 1399 EEDVAELSISPSDNAVVLTNLLPGTEYV-VSVSSV--YEQHESTPLRGRQKTGLDSPTGI 1455
            EE   E  +    N + L+N++    Y  V++SS+   E      ++   K  +D    +
Sbjct: 270  EELTKEDEMPVGRNVLELSNVVRSANYTCVAISSLGMIEATAQVTVKALPKPPID----L 325

Query: 1456 DFSDITANSFTVHWIAPRAT-ITGYRIRHHPEHFSGRPRE-DRVPHSRNSITLTNLTPGT 1513
              ++ TA S T+ W +  +  +T Y I++      G  +E D V  +R SI    L+P +
Sbjct: 326  VVTETTATSVTLTWDSGNSEPVTYYGIQYRAAGTEGPFQEVDGVATTRYSIG--GLSPFS 383

Query: 1514 EYVVSIVALNGREESP------LLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVT-- 1565
            EY   ++A+N     P         G+Q+  S  PR ++    + +++L+ W+ P     
Sbjct: 384  EYAFRVLAVNSIGRGPPSEAVRARTGEQAP-SSPPRRVQARMLSASTMLVQWEPPEEPNG 442

Query: 1566 -VRYYRITYGETGGNSPV---QEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPAS 1621
             VR YR+ Y       P    +  T  G  +T  +  L PG+ Y++ V A T  GD P S
Sbjct: 443  LVRGYRVYYTPDSRRPPNAWHKHNTDAGLLTT--VGSLLPGITYSLRVLAFTAVGDGPPS 500

Query: 1622 SKPISINYRTEIDKPSQ---MQVTDVQDNSISVKWL-PSSSPVTGYRVTTTPKNGPGPTK 1677
                +I  +T+   P+Q    Q     D  I + WL P    +  Y +            
Sbjct: 501  P---TIQVKTQQGVPAQPADFQAEVESDTRIQLSWLLPPQERIIMYELVYWAAEDEDQQH 557

Query: 1678 TKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGES--QPLVQTAV---TNIDRPKGLAFT 1732
              T  P  +  T+E L+P   Y   + A++  G     P ++      T    P+ +   
Sbjct: 558  KVTFDPTSS-YTLEDLKPDTLYRFQLAARSDMGVGVFTPTIEARTAQSTPSAPPQKVMCV 616

Query: 1733 DVDVDSIKIAWESP-----QGQVSRYRVTYSSP--EDGIHELFPAPDGEEDTAELQGLRP 1785
             +   +++++W  P      G +++Y V Y +   ED    +      E  + +L GL  
Sbjct: 617  SMGSTTVRVSWVPPPADSRNGVITQYSVAYEAVDGEDRGRHVVDGISREHSSWDLVGLEK 676

Query: 1786 GSEYTVSVVALHDDM----ESQPLIGTQSTAIPA--PTDLKFTQVTPTSLSAQWTPP--- 1836
             +EY V V A H D+    ES P++      +P+  P  ++   +  T++   W  P   
Sbjct: 677  WTEYRVWVRA-HTDVGPGPESSPVLVRTDEDVPSGPPRKVEVEPLNSTAVHVYWKLPVPS 735

Query: 1837 --NVQLTGYRVRVTPKEKTGP-----MKEINLAPDSSSVVVSGLMVATKYEVSVYALK-- 1887
              + Q+ GY+V     E   P     ++++ LA ++    +SGL   T Y V+V A    
Sbjct: 736  KQHGQIRGYQVTYVRLENGEPRGLPIIQDVMLA-EAQETTISGLTPETTYSVTVAAYTTK 794

Query: 1888 -DTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTET---ITGFQVDAVPAN 1943
             D   S+P   +VTT   V       ++     T  + W    E    + G+++    A+
Sbjct: 795  GDGARSKPK--IVTTTGAVPGRPTMMISTTAMNTALLQWHPPKELPGELLGYRLQYCRAD 852

Query: 1944 GQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPS----N 1999
               P       D + +T+TGL  GT Y   L   N          +  T  D PS    N
Sbjct: 853  EARPNTIDFGKDDQHFTVTGLHKGTTYIFRLAAKNRAGLGEEFEKEIRTPEDLPSGFPQN 912

Query: 2000 LRFLATTPNSLLVSWQPP-----RARITGYIIKYEKPGSPPREVVPRPRPGVTEATITGL 2054
            L     T ++  ++W PP       RI  Y + +    S   +   +     T  T+TGL
Sbjct: 913  LHVTGLTTSTTELAWDPPVLAERNGRIISYTVVFRDINS---QQELQNITTDTRFTLTGL 969

Query: 2055 EPGTEYTIYVIA 2066
            +P T Y I V A
Sbjct: 970  KPDTTYDIKVRA 981



 Score =  130 bits (326), Expect = 2e-29
 Identities = 196/837 (23%), Positives = 330/837 (39%), Gaps = 80/837 (9%)

Query: 862  ANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQ----ETTGTPRSDTVPSPR-DLQFV 916
            A  +T  D  P  +  + +  V  +   T V I      E T       +P P  DL   
Sbjct: 269  AEELTKEDEMPVGRNVLELSNVVRSANYTCVAISSLGMIEATAQVTVKALPKPPIDLVVT 328

Query: 917  EVTDVKVTIMWTPPESA-VTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYF 975
            E T   VT+ W    S  VT Y +        G   Q +     T   + GLSP   Y F
Sbjct: 329  ETTATSVTLTWDSGNSEPVTYYGIQYRAAGTEGPF-QEVDGVATTRYSIGGLSPFSEYAF 387

Query: 976  KVFAVS---HGRESKPLTAQ--QTTKLDAPTNLQFVNETDSTVLVRWTP---PRAQITGY 1027
            +V AV+    G  S+ + A+  +      P  +Q    + ST+LV+W P   P   + GY
Sbjct: 388  RVLAVNSIGRGPPSEAVRARTGEQAPSSPPRRVQARMLSASTMLVQWEPPEEPNGLVRGY 447

Query: 1028 RLTVGLTRRGQP---RQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTT 1084
            R+      R  P    ++N    +    + +L P   Y++ ++A     + P +  +   
Sbjct: 448  RVYYTPDSRRPPNAWHKHNTDAGLLT-TVGSLLPGITYSLRVLAFTAVGDGPPSPTIQVK 506

Query: 1085 LQPGSSIPP--YNTEV-TETTIVITWTPAPR---IGFKLGVRPSQGGEAPREVTSD-SGS 1137
             Q G    P  +  EV ++T I ++W   P+   I ++L    ++  +   +VT D + S
Sbjct: 507  TQQGVPAQPADFQAEVESDTRIQLSWLLPPQERIIMYELVYWAAEDEDQQHKVTFDPTSS 566

Query: 1138 IVVSGLTPGVEYVYTIQVLRD-GQERDAPIVNKVV---TPLSPPTNLHLEANPDTGVLTV 1193
              +  L P   Y + +    D G     P +       TP +PP  +   +   T V  V
Sbjct: 567  YTLEDLKPDTLYRFQLAARSDMGVGVFTPTIEARTAQSTPSAPPQKVMCVSMGSTTV-RV 625

Query: 1194 SW----ERSTTPDITGYRITTTPTNGQ-QGNSLEEVVHADQSSCTFDNLSPGLEYNVSVY 1248
            SW      S    IT Y +     +G+ +G  + + +  + SS     L    EY V V 
Sbjct: 626  SWVPPPADSRNGVITQYSVAYEAVDGEDRGRHVVDGISREHSSWDLVGLEKWTEYRVWVR 685

Query: 1249 TVKD---DKESVPI---SDTIIPEVPQLTDLSFVDITDSSIGLRW-TPLNS---STIIGY 1298
               D     ES P+   +D  +P  P    +    +  +++ + W  P+ S     I GY
Sbjct: 686  AHTDVGPGPESSPVLVRTDEDVPSGPP-RKVEVEPLNSTAVHVYWKLPVPSKQHGQIRGY 744

Query: 1299 RITVVAA--GE--GIPIFEDFVDSSVGYYTVTGLEPGIDYDISV---ITLINGGESAPTT 1351
            ++T V    GE  G+PI +D + +     T++GL P   Y ++V    T  +G  S P  
Sbjct: 745  QVTYVRLENGEPRGLPIIQDVMLAEAQETTISGLTPETTYSVTVAAYTTKGDGARSKPKI 804

Query: 1352 LTQQTAVPPPTDLRFTNIGPDTMRVTWAPPPSI--DLTNFLVRYSPVKNEEDVAELSISP 1409
            +T   AVP    +  +    +T  + W PP  +  +L  + ++Y    +E     +    
Sbjct: 805  VTTTGAVPGRPTMMISTTAMNTALLQWHPPKELPGELLGYRLQYCRA-DEARPNTIDFGK 863

Query: 1410 SDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTG----IDFSDITANSF 1465
             D    +T L  GT Y+  +++              +T  D P+G    +  + +T ++ 
Sbjct: 864  DDQHFTVTGLHKGTTYIFRLAAKNRAGLGEEFEKEIRTPEDLPSGFPQNLHVTGLTTSTT 923

Query: 1466 TVHWIAPRATITGYRIRHHPEHFSGRPREDRVPH--SRNSITLTNLTPGTEYVVSIVALN 1523
             + W  P       RI  +   F     +  + +  +    TLT L P T Y + + A  
Sbjct: 924  ELAWDPPVLAERNGRIISYTVVFRDINSQQELQNITTDTRFTLTGLKPDTTYDIKVRAWT 983

Query: 1524 GREESPLLIGQQSTVSDV----PRDLEVVAATPTSLLISWDAP--AVTVRYYRITYGETG 1577
             +   PL    QS    V     ++  V AA  TS+L+SW+ P    +   ++I Y    
Sbjct: 984  SKGSGPLSPSIQSRTMPVEQVFAKNFRVAAAMKTSVLLSWEVPDSYKSAVPFKILYNG-- 1041

Query: 1578 GNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEID 1634
                 Q   V G      I+ L+P  +Y+   + +  RG S    + + ++ RT  D
Sbjct: 1042 -----QSVEVDGHSMRKLIADLQPNTEYS---FVLMNRGSSAGGLQHL-VSIRTAPD 1089



 Score =  117 bits (294), Expect = 1e-25
 Identities = 183/802 (22%), Positives = 332/802 (41%), Gaps = 100/802 (12%)

Query: 1264 IPEVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIFEDFVDSSVGYY 1323
            +P+ P   DL   + T +S+ L W   NS  +  Y I   AAG   P F++    +   Y
Sbjct: 318  LPKPP--IDLVVTETTATSVTLTWDSGNSEPVTYYGIQYRAAGTEGP-FQEVDGVATTRY 374

Query: 1324 TVTGLEPGIDYDISVITLINGGESAPTTLT-----QQTAVPPPTDLRFTNIGPDTMRVTW 1378
            ++ GL P  +Y   V+ + + G   P+        +Q    PP  ++   +   TM V W
Sbjct: 375  SIGGLSPFSEYAFRVLAVNSIGRGPPSEAVRARTGEQAPSSPPRRVQARMLSASTMLVQW 434

Query: 1379 APP--PSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLT--NLLPGTEY---VVSVSS 1431
             PP  P+  +  + V Y+P       A    + +D  ++ T  +LLPG  Y   V++ ++
Sbjct: 435  EPPEEPNGLVRGYRVYYTPDSRRPPNAWHKHN-TDAGLLTTVGSLLPGITYSLRVLAFTA 493

Query: 1432 VYEQHESTPLRGRQKTGLDSPTGIDFSDITANS-FTVHWIAP-RATITGYRIRHHPEHFS 1489
            V +   S  ++ + + G+ +      +++ +++   + W+ P +  I  Y + +      
Sbjct: 494  VGDGPPSPTIQVKTQQGVPAQPADFQAEVESDTRIQLSWLLPPQERIIMYELVYWAAEDE 553

Query: 1490 GRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREE---SPLLIGQ--QSTVSDVPRD 1544
             +  +     + +S TL +L P T Y   + A +       +P +  +  QST S  P+ 
Sbjct: 554  DQQHKVTFDPT-SSYTLEDLKPDTLYRFQLAARSDMGVGVFTPTIEARTAQSTPSAPPQK 612

Query: 1545 LEVVAATPTSLLISWDAPAVTVR-----YYRITY----GETGGNSPVQEFTVPGSKSTAT 1595
            +  V+   T++ +SW  P    R      Y + Y    GE  G   V    +    S+  
Sbjct: 613  VMCVSMGSTTVRVSWVPPPADSRNGVITQYSVAYEAVDGEDRGRHVVDG--ISREHSSWD 670

Query: 1596 ISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPS----QMQVTDVQDNSISV 1651
            + GL+   +Y + V A T  G  P SS P+ +  RT+ D PS    +++V  +   ++ V
Sbjct: 671  LVGLEKWTEYRVWVRAHTDVGPGPESS-PVLV--RTDEDVPSGPPRKVEVEPLNSTAVHV 727

Query: 1652 KW---LPSSS--PVTGYRVTTTP-KNGPG---PTKTKTAGPDQTEMTIEGLQPTVEYVVS 1702
             W   +PS     + GY+VT    +NG     P        +  E TI GL P   Y V+
Sbjct: 728  YWKLPVPSKQHGQIRGYQVTYVRLENGEPRGLPIIQDVMLAEAQETTISGLTPETTYSVT 787

Query: 1703 VYAQNPSGE---SQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQ---GQVSRYRVT 1756
            V A    G+   S+P + T    +     +  +   +++  + W  P+   G++  YR+ 
Sbjct: 788  VAAYTTKGDGARSKPKIVTTTGAVPGRPTMMISTTAMNTALLQWHPPKELPGELLGYRLQ 847

Query: 1757 YSSPEDGIHELFPAPDGEEDTA-ELQGLRPGSEYTVSVVA-----LHDDMESQPLIGTQS 1810
            Y   ++          G++D    + GL  G+ Y   + A     L ++ E + +   + 
Sbjct: 848  YCRADEARPNTIDF--GKDDQHFTVTGLHKGTTYIFRLAAKNRAGLGEEFEKE-IRTPED 904

Query: 1811 TAIPAPTDLKFTQVTPTSLSAQWTPP-----NVQLTGYRVRVTPKEKTGPMKEINLAPDS 1865
                 P +L  T +T ++    W PP     N ++  Y V           +E+      
Sbjct: 905  LPSGFPQNLHVTGLTTSTTELAWDPPVLAERNGRIISYTVVF---RDINSQQELQNITTD 961

Query: 1866 SSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPP------RRARVTDATET 1919
            +   ++GL   T Y++ V A     TS+ +  +  ++++ + P      +  RV  A +T
Sbjct: 962  TRFTLTGLKPDTTYDIKVRAW----TSKGSGPLSPSIQSRTMPVEQVFAKNFRVAAAMKT 1017

Query: 1920 TITISWRTKTETITGFQVDAVPA----NGQTPIQRTIKPDVRSYT--ITGLQPGTDYKIY 1973
            ++ +SW      +      AVP     NGQ+     ++ D  S    I  LQP T+Y   
Sbjct: 1018 SVLLSWE-----VPDSYKSAVPFKILYNGQS-----VEVDGHSMRKLIADLQPNTEYSFV 1067

Query: 1974 LYTLNDNARSSPVVIDASTAID 1995
            L     +A     ++   TA D
Sbjct: 1068 LMNRGSSAGGLQHLVSIRTAPD 1089



 Score =  115 bits (289), Expect = 4e-25
 Identities = 183/799 (22%), Positives = 303/799 (37%), Gaps = 81/799 (10%)

Query: 1053 LRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPA-- 1110
            L N+  ++ YT   ++  G  E+     V    +P   I    TE T T++ +TW     
Sbjct: 287  LSNVVRSANYTCVAISSLGMIEATAQVTVKALPKP--PIDLVVTETTATSVTLTWDSGNS 344

Query: 1111 -PRIGFKLGVRPSQGGEAPREVTSDSGSI--VVSGLTPGVEYVYTIQVLRD-GQERDAPI 1166
             P   + +  R + G E P +      +    + GL+P  EY + +  +   G+   +  
Sbjct: 345  EPVTYYGIQYRAA-GTEGPFQEVDGVATTRYSIGGLSPFSEYAFRVLAVNSIGRGPPSEA 403

Query: 1167 VNKVV---TPLSPPTNLHLEANPDTGVLTVSWERSTTPD--ITGYRITTTPTNGQQGNSL 1221
            V        P SPP  +       + +L V WE    P+  + GYR+  TP + +  N+ 
Sbjct: 404  VRARTGEQAPSSPPRRVQARMLSASTML-VQWEPPEEPNGLVRGYRVYYTPDSRRPPNAW 462

Query: 1222 EEVVHADQSSCTFDNLSPGLEYNVSVYT---VKDDKESVPISDTIIPEVP-QLTDLSFVD 1277
             +         T  +L PG+ Y++ V     V D   S  I       VP Q  D     
Sbjct: 463  HKHNTDAGLLTTVGSLLPGITYSLRVLAFTAVGDGPPSPTIQVKTQQGVPAQPADFQAEV 522

Query: 1278 ITDSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDY--D 1335
             +D+ I L W       II Y +   AA +     +   D +  Y T+  L+P   Y   
Sbjct: 523  ESDTRIQLSWLLPPQERIIMYELVYWAAEDEDQQHKVTFDPTSSY-TLEDLKPDTLYRFQ 581

Query: 1336 ISVITLINGGESAPTT---LTQQTAVPPPTDLRFTNIGPDTMRVTWAPPPSID----LTN 1388
            ++  + +  G   PT      Q T   PP  +   ++G  T+RV+W PPP+      +T 
Sbjct: 582  LAARSDMGVGVFTPTIEARTAQSTPSAPPQKVMCVSMGSTTVRVSWVPPPADSRNGVITQ 641

Query: 1389 FLVRYSPVKNEEDVAEL--SISPSDNAVVLTNLLPGTEYVVSV---SSVYEQHESTPLRG 1443
            + V Y  V  E+    +   IS   ++  L  L   TEY V V   + V    ES+P+  
Sbjct: 642  YSVAYEAVDGEDRGRHVVDGISREHSSWDLVGLEKWTEYRVWVRAHTDVGPGPESSPVLV 701

Query: 1444 RQKTGLDS--PTGIDFSDITANSFTVHWIAP-----RATITGYRIRHHPEHFSGRPR--- 1493
            R    + S  P  ++   + + +  V+W  P        I GY++  +    +G PR   
Sbjct: 702  RTDEDVPSGPPRKVEVEPLNSTAVHVYWKLPVPSKQHGQIRGYQVT-YVRLENGEPRGLP 760

Query: 1494 --EDRVPHSRNSITLTNLTPGTEYVVSIVAL----NGREESPLLIGQQSTVSDVPRDLEV 1547
              +D +       T++ LTP T Y V++ A     +G    P ++     V   P  +  
Sbjct: 761  IIQDVMLAEAQETTISGLTPETTYSVTVAAYTTKGDGARSKPKIVTTTGAVPGRPTMMIS 820

Query: 1548 VAATPTSLLISWDAPAV---TVRYYRITYGETGGNSPVQEFTVPGSKSTA--TISGLKPG 1602
              A  T+LL  W  P      +  YR+ Y       P    T+   K     T++GL  G
Sbjct: 821  TTAMNTALL-QWHPPKELPGELLGYRLQYCRADEARP---NTIDFGKDDQHFTVTGLHKG 876

Query: 1603 VDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLP-----SS 1657
              Y   + A    G      K I          P  + VT +  ++  + W P      +
Sbjct: 877  TTYIFRLAAKNRAGLGEEFEKEIRTPEDLPSGFPQNLHVTGLTTSTTELAWDPPVLAERN 936

Query: 1658 SPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSV--YAQNPSGESQPL 1715
              +  Y V     N     +  T     T  T+ GL+P   Y + V  +    SG   P 
Sbjct: 937  GRIISYTVVFRDINSQQELQNITT---DTRFTLTGLKPDTTYDIKVRAWTSKGSGPLSPS 993

Query: 1716 VQTAVTNIDR--PKGLAFTDVDVDSIKIAWESPQGQVSR--YRVTYSSPEDGIHELFPAP 1771
            +Q+    +++   K          S+ ++WE P    S   +++ Y+     +       
Sbjct: 994  IQSRTMPVEQVFAKNFRVAAAMKTSVLLSWEVPDSYKSAVPFKILYNGQSVEV------- 1046

Query: 1772 DGEEDTAELQGLRPGSEYT 1790
            DG      +  L+P +EY+
Sbjct: 1047 DGHSMRKLIADLQPNTEYS 1065



 Score =  104 bits (259), Expect = 1e-21
 Identities = 164/774 (21%), Positives = 288/774 (37%), Gaps = 83/774 (10%)

Query: 990  TAQQTTKL--DAPTNLQFVNETDSTVLVRWTPPRAQ-ITGYRLTVGLTRRGQPRQYNVGP 1046
            TAQ T K     P +L     T ++V + W    ++ +T Y +         P Q   G 
Sbjct: 310  TAQVTVKALPKPPIDLVVTETTATSVTLTWDSGNSEPVTYYGIQYRAAGTEGPFQEVDGV 369

Query: 1047 SVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGV-FTTLQPGSSIPPYNTE---VTETT 1102
            + ++Y +  L P SEY   ++A+      P +  V   T +   S PP   +   ++ +T
Sbjct: 370  ATTRYSIGGLSPFSEYAFRVLAVNSIGRGPPSEAVRARTGEQAPSSPPRRVQARMLSAST 429

Query: 1103 IVITWTPAPR-----IGFKLGVRPS--QGGEAPREVTSDSGSI-VVSGLTPGVEY---VY 1151
            +++ W P         G+++   P   +   A  +  +D+G +  V  L PG+ Y   V 
Sbjct: 430  MLVQWEPPEEPNGLVRGYRVYYTPDSRRPPNAWHKHNTDAGLLTTVGSLLPGITYSLRVL 489

Query: 1152 TIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTT 1211
                + DG       V       + P +   E   DT +  +SW       I  Y +   
Sbjct: 490  AFTAVGDGPPSPTIQVKTQQGVPAQPADFQAEVESDTRI-QLSWLLPPQERIIMYELVYW 548

Query: 1212 PTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPEVPQLT 1271
                +  +   +V     SS T ++L P   Y   +   + D      + TI     Q T
Sbjct: 549  AAEDE--DQQHKVTFDPTSSYTLEDLKPDTLYRFQL-AARSDMGVGVFTPTIEARTAQST 605

Query: 1272 ------DLSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIFE------DFVDSS 1319
                   +  V +  +++ + W P  + +  G       A E +   +      D +   
Sbjct: 606  PSAPPQKVMCVSMGSTTVRVSWVPPPADSRNGVITQYSVAYEAVDGEDRGRHVVDGISRE 665

Query: 1320 VGYYTVTGLEPGIDYDISVITLIN---GGESAPTTLTQQTAVP--PPTDLRFTNIGPDTM 1374
               + + GLE   +Y + V    +   G ES+P  +     VP  PP  +    +    +
Sbjct: 666  HSSWDLVGLEKWTEYRVWVRAHTDVGPGPESSPVLVRTDEDVPSGPPRKVEVEPLNSTAV 725

Query: 1375 RVTW-APPPSI---DLTNFLVRYSPVKNEED-----VAELSISPSDNAVVLTNLLPGTEY 1425
             V W  P PS     +  + V Y  ++N E      + ++ ++ +    + + L P T Y
Sbjct: 726  HVYWKLPVPSKQHGQIRGYQVTYVRLENGEPRGLPIIQDVMLAEAQETTI-SGLTPETTY 784

Query: 1426 VVSVSSVYEQHESTPLRGRQKTGLDSPTG-------IDFSDITANSFTVHWIAPR---AT 1475
             V+V++   + +      R K  + + TG       +  S    N+  + W  P+     
Sbjct: 785  SVTVAAYTTKGDG----ARSKPKIVTTTGAVPGRPTMMISTTAMNTALLQWHPPKELPGE 840

Query: 1476 ITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN----GREESPLL 1531
            + GYR+++       RP            T+T L  GT Y+  + A N    G E    +
Sbjct: 841  LLGYRLQYCRAD-EARPNTIDFGKDDQHFTVTGLHKGTTYIFRLAAKNRAGLGEEFEKEI 899

Query: 1532 IGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVR-----YYRITYGETGGNSPVQEFT 1586
               +   S  P++L V   T ++  ++WD P +  R      Y + + +      +Q  T
Sbjct: 900  RTPEDLPSGFPQNLHVTGLTTSTTELAWDPPVLAERNGRIISYTVVFRDINSQQELQNIT 959

Query: 1587 VPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQD 1646
               + +  T++GLKP   Y I V A T +G  P S    S     E       +V     
Sbjct: 960  ---TDTRFTLTGLKPDTTYDIKVRAWTSKGSGPLSPSIQSRTMPVEQVFAKNFRVAAAMK 1016

Query: 1647 NSISVKW-LPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEY 1699
             S+ + W +P S     Y+     K        +  G    ++ I  LQP  EY
Sbjct: 1017 TSVLLSWEVPDS-----YKSAVPFKILYNGQSVEVDGHSMRKL-IADLQPNTEY 1064



 Score = 86.7 bits (213), Expect = 3e-16
 Identities = 125/566 (22%), Positives = 223/566 (39%), Gaps = 67/566 (11%)

Query: 628  IQWNAPQPSHISKY-ILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQ 686
            + W  P    I  Y ++ W  ++   + K    P   +SYT++ LKP  +Y  QL +   
Sbjct: 530  LSWLLPPQERIIMYELVYWAAEDEDQQHKVTFDP--TSSYTLEDLKPDTLYRFQLAARSD 587

Query: 687  YGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWV----- 741
             G    T      T+ STP         + P   ++  S   T +      VSWV     
Sbjct: 588  MGVGVFTPTIEARTAQSTP---------SAPPQKVMCVSMGSTTVR-----VSWVPPPAD 633

Query: 742  SASDTVSGFRVEYELSEEGDEPQYL--DLPSTATSVNIPDLLPGRKYIVNVYQISEDG-- 797
            S +  ++ + V YE  +  D  +++   +    +S ++  L    +Y V V   ++ G  
Sbjct: 634  SRNGVITQYSVAYEAVDGEDRGRHVVDGISREHSSWDLVGLEKWTEYRVWVRAHTDVGPG 693

Query: 798  -EQSLILSTSQTTAPDAPPDPT-VDQVDDTSIVVRW-----SRPQAPITGYRIVYSPSVE 850
             E S +L  +    P  PP    V+ ++ T++ V W     S+    I GY++ Y     
Sbjct: 694  PESSPVLVRTDEDVPSGPPRKVEVEPLNSTAVHVYWKLPVPSKQHGQIRGYQVTYVRLEN 753

Query: 851  GSSTELNLPE-----TANSVTLSDLQPGVQYNITIYAVE---ENQESTPVVIQQETTGTP 902
            G    L + +      A   T+S L P   Y++T+ A     +   S P ++   TTG  
Sbjct: 754  GEPRGLPIIQDVMLAEAQETTISGLTPETTYSVTVAAYTTKGDGARSKPKIV--TTTG-- 809

Query: 903  RSDTVPSPRDLQFVEVTDVKVTIM-WTPPE---SAVTGYRVDVIPVNLPGEHGQRLPISR 958
                VP  R    +  T +   ++ W PP+     + GYR+     +    +        
Sbjct: 810  ---AVPG-RPTMMISTTAMNTALLQWHPPKELPGELLGYRLQYCRADEARPNTIDFGKDD 865

Query: 959  NTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPT----NLQFVNETDSTVL 1014
              F  VTGL  G TY F++ A +     +    +  T  D P+    NL     T ST  
Sbjct: 866  QHFT-VTGLHKGTTYIFRLAAKNRAGLGEEFEKEIRTPEDLPSGFPQNLHVTGLTTSTTE 924

Query: 1015 VRWTPP-RAQITGYRLTVGLTRR---GQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIK 1070
            + W PP  A+  G  ++  +  R    Q    N+  + +++ L  L+P + Y + + A  
Sbjct: 925  LAWDPPVLAERNGRIISYTVVFRDINSQQELQNI-TTDTRFTLTGLKPDTTYDIKVRAWT 983

Query: 1071 GNQESPKATGVFTTLQPGSSIPPYNTEVT---ETTIVITWTPAPRIGFKLGVRPSQGGEA 1127
                 P +  + +   P   +   N  V    +T+++++W         +  +    G++
Sbjct: 984  SKGSGPLSPSIQSRTMPVEQVFAKNFRVAAAMKTSVLLSWEVPDSYKSAVPFKILYNGQS 1043

Query: 1128 PREVTSDSGSIVVSGLTPGVEYVYTI 1153
              EV   S   +++ L P  EY + +
Sbjct: 1044 V-EVDGHSMRKLIADLQPNTEYSFVL 1068


>gi|112734845 collagen, type XX, alpha 1 [Homo sapiens]
          Length = 1284

 Score =  152 bits (383), Expect = 5e-36
 Identities = 136/474 (28%), Positives = 209/474 (44%), Gaps = 22/474 (4%)

Query: 1258 PISDTIIPEVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIFEDFVD 1317
            P +   +  +P  T L    +T SSI L WTP     +  Y I   A+  G P  E  V+
Sbjct: 368  PAAAPALDTLPAPTSLVLSQVTSSSIRLSWTPAPRHPL-KYLIVWRASRGGTPR-EVVVE 425

Query: 1318 SSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTA-VPPPTDLRFTNIGPDTMRV 1376
                   +  L    +Y +SV  +  GG          TA +PPP  L    + P T+ +
Sbjct: 426  GPAASTELHNLASRTEYLVSVFPIYEGGVGEGLRGLVTTAPLPPPRALTLAAVTPRTVHL 485

Query: 1377 TWAPPPSIDLTNFLVRYSPV--KNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVY- 1433
            TW P  S   T++LVR SP   K EE+  E+ +   +  V+L  L PG +Y VSV S+  
Sbjct: 486  TWQP--SAGATHYLVRCSPASPKGEEEEREVQVGRPE--VLLDGLEPGRDYEVSVQSLRG 541

Query: 1434 -EQHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRP 1492
             E  E+  +R R  T L  P  + FSD++ ++  V W      +   R+ +      G  
Sbjct: 542  PEGSEARGIRARTPT-LAPPRHLGFSDVSHDAARVFWEGAPRPVRLVRVTYVSSE-GGHS 599

Query: 1493 REDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTV-SDVPRDLEVVAAT 1551
             +   P +  S TL  L+  T Y V +  L     S  L G+ +T  +  P  L +    
Sbjct: 600  GQTEAPGNATSATLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVTTKKAPSPSQLSMTELP 659

Query: 1552 PTSLLISWDAPAVT-VRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVY 1610
              ++ ++W A A + V  Y+IT+   G      E +VPG+  TA + GL    +Y +T+ 
Sbjct: 660  GDAVQLAWVAAAPSGVLVYQITWTPLG-EGKAHEISVPGNLGTAVLPGLGRHTEYDVTIL 718

Query: 1611 AVTGRGDSPASSKPISINYRTEI---DKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTT 1667
            A    G   A S P+S+ Y         PS + +     +S+ V W P    V  Y +T 
Sbjct: 719  AYYRDG---ARSDPVSLRYTPSTVSRSPPSNLALASETPDSLQVSWTPPLGRVLHYWLTY 775

Query: 1668 TPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVT 1721
             P +G GP K+ +    ++ +T+  LQ   +Y V V A   +G S+ +  T  T
Sbjct: 776  APASGLGPEKSVSVPGARSHVTLPDLQAATKYRVLVSAIYAAGRSEAVSATGQT 829



 Score =  146 bits (369), Expect = 2e-34
 Identities = 133/449 (29%), Positives = 203/449 (45%), Gaps = 22/449 (4%)

Query: 1449 LDSPTGIDFSDITANSFTVHWI-APRATITGYRIRHHPEHFSGRPREDRVPHSRNSITLT 1507
            L +PT +  S +T++S  + W  APR  +  Y I        G PRE  V     S  L 
Sbjct: 377  LPAPTSLVLSQVTSSSIRLSWTPAPRHPLK-YLIVWRASR-GGTPREVVVEGPAASTELH 434

Query: 1508 NLTPGTEYVVSIVALNGREESPLLIGQQSTVS-DVPRDLEVVAATPTSLLISWDAPAVTV 1566
            NL   TEY+VS+  +        L G  +T     PR L + A TP ++ ++W  P+   
Sbjct: 435  NLASRTEYLVSVFPIYEGGVGEGLRGLVTTAPLPPPRALTLAAVTPRTVHLTWQ-PSAGA 493

Query: 1567 RYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPIS 1626
             +Y +           +E  V   +    + GL+PG DY ++V ++ G    P  S+   
Sbjct: 494  THYLVRCSPASPKGEEEEREVQVGRPEVLLDGLEPGRDYEVSVQSLRG----PEGSEARG 549

Query: 1627 INYRTE-IDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQ 1685
            I  RT  +  P  +  +DV  ++  V W  +  PV   RVT     G    +T+  G + 
Sbjct: 550  IRARTPTLAPPRHLGFSDVSHDAARVFWEGAPRPVRLVRVTYVSSEGGHSGQTEAPG-NA 608

Query: 1686 TEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTN-IDRPKGLAFTDVDVDSIKIAW- 1743
            T  T+  L  +  Y V V    P G S  L     T     P  L+ T++  D++++AW 
Sbjct: 609  TSATLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVTTKKAPSPSQLSMTELPGDAVQLAWV 668

Query: 1744 -ESPQGQVSRYRVTYSSPEDG-IHELFPAPDGEEDTAELQGLRPGSEYTVSVVALH-DDM 1800
              +P G V  Y++T++   +G  HE+  +  G   TA L GL   +EY V+++A + D  
Sbjct: 669  AAAPSG-VLVYQITWTPLGEGKAHEI--SVPGNLGTAVLPGLGRHTEYDVTILAYYRDGA 725

Query: 1801 ESQP--LIGTQSTAIPAP-TDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMK 1857
             S P  L  T ST   +P ++L     TP SL   WTPP  ++  Y +   P    GP K
Sbjct: 726  RSDPVSLRYTPSTVSRSPPSNLALASETPDSLQVSWTPPLGRVLHYWLTYAPASGLGPEK 785

Query: 1858 EINLAPDSSSVVVSGLMVATKYEVSVYAL 1886
             +++    S V +  L  ATKY V V A+
Sbjct: 786  SVSVPGARSHVTLPDLQAATKYRVLVSAI 814



 Score =  136 bits (343), Expect = 2e-31
 Identities = 119/472 (25%), Positives = 203/472 (43%), Gaps = 22/472 (4%)

Query: 988  PLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPS 1047
            P  A     L APT+L     T S++ + WTP       Y +    +R G PR+  V   
Sbjct: 368  PAAAPALDTLPAPTSLVLSQVTSSSIRLSWTPAPRHPLKYLIVWRASRGGTPREVVVEGP 427

Query: 1048 VSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYN----TEVTETTI 1103
             +   L NL   +EY VS+  I          G+ TT    + +PP        VT  T+
Sbjct: 428  AASTELHNLASRTEYLVSVFPIYEGGVGEGLRGLVTT----APLPPPRALTLAAVTPRTV 483

Query: 1104 VITWTP---APRIGFKLGVRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQ 1160
             +TW P   A     +      +G E  REV      +++ GL PG +Y  ++Q LR  +
Sbjct: 484  HLTWQPSAGATHYLVRCSPASPKGEEEEREVQVGRPEVLLDGLEPGRDYEVSVQSLRGPE 543

Query: 1161 ERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNS 1220
              +A  +      L+PP +L   ++       V WE +  P +   R+T   + G  G+S
Sbjct: 544  GSEARGIRARTPTLAPPRHLGF-SDVSHDAARVFWEGAPRP-VRLVRVTYVSSEG--GHS 599

Query: 1221 LEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTI-IPEVPQLTDLSFVDIT 1279
             +     + +S T   LS    Y V V  +     S  ++  +   + P  + LS  ++ 
Sbjct: 600  GQTEAPGNATSATLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVTTKKAPSPSQLSMTELP 659

Query: 1280 DSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVI 1339
              ++ L W     S ++ Y+IT    GEG    E  V  ++G   + GL    +YD++++
Sbjct: 660  GDAVQLAWVAAAPSGVLVYQITWTPLGEG-KAHEISVPGNLGTAVLPGLGRHTEYDVTIL 718

Query: 1340 TLI-NGGESAPTTLTQQTAV---PPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSP 1395
                +G  S P +L    +     PP++L   +  PD+++V+W PP    + ++ + Y+P
Sbjct: 719  AYYRDGARSDPVSLRYTPSTVSRSPPSNLALASETPDSLQVSWTPPLG-RVLHYWLTYAP 777

Query: 1396 VKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKT 1447
                     +S+  + + V L +L   T+Y V VS++Y    S  +    +T
Sbjct: 778  ASGLGPEKSVSVPGARSHVTLPDLQAATKYRVLVSAIYAAGRSEAVSATGQT 829



 Score =  133 bits (335), Expect = 2e-30
 Identities = 145/529 (27%), Positives = 230/529 (43%), Gaps = 36/529 (6%)

Query: 1115 FKLGVRPSQGGEA------PREVTSDSG-SIVVSGLTPGVEYVYTIQVLRDGQERDAPIV 1167
            F +GV+ +   E       PR++T  S    +  G   G+      Q L+ G  R  P  
Sbjct: 311  FAVGVKNADEAELRLLASPPRDITVHSVLDFLQLGALAGLLSRLICQRLQGGSPRQGPAA 370

Query: 1168 NKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHA 1227
               +  L  PT+L L     + +  +SW  +    +  Y I    + G  G   E VV  
Sbjct: 371  APALDTLPAPTSLVLSQVTSSSI-RLSWTPAPRHPLK-YLIVWRASRG--GTPREVVVEG 426

Query: 1228 DQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPE-VPQLTDLSFVDITDSSIGLR 1286
              +S    NL+   EY VSV+ + +      +   +    +P    L+   +T  ++ L 
Sbjct: 427  PAASTELHNLASRTEYLVSVFPIYEGGVGEGLRGLVTTAPLPPPRALTLAAVTPRTVHLT 486

Query: 1287 WTPLNSSTIIGYRITVVAA-GEGIPIFEDFVDSSVGYYTVT--GLEPGIDYDISVITLIN 1343
            W P   +T    R +  +  GE     E+  +  VG   V   GLEPG DY++SV +L  
Sbjct: 487  WQPSAGATHYLVRCSPASPKGE-----EEEREVQVGRPEVLLDGLEPGRDYEVSVQSLRG 541

Query: 1344 G-GESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTW--APPPSIDLTNFLVRYSPVKNEE 1400
              G  A     +   + PP  L F+++  D  RV W  AP P       LVR + V +E 
Sbjct: 542  PEGSEARGIRARTPTLAPPRHLGFSDVSHDAARVFWEGAPRPVR-----LVRVTYVSSEG 596

Query: 1401 DVAELSISPSD-NAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTG-LDSPTGIDFS 1458
              +  + +P +  +  L  L   T Y V V+ +Y    S+ L GR  T    SP+ +  +
Sbjct: 597  GHSGQTEAPGNATSATLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVTTKKAPSPSQLSMT 656

Query: 1459 DITANSFTVHWIAPRAT-ITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVV 1517
            ++  ++  + W+A   + +  Y+I   P    G+  E  VP +  +  L  L   TEY V
Sbjct: 657  ELPGDAVQLAWVAAAPSGVLVYQITWTPLG-EGKAHEISVPGNLGTAVLPGLGRHTEYDV 715

Query: 1518 SIVAL--NGREESPLLIGQQ-STVS-DVPRDLEVVAATPTSLLISWDAPAVTVRYYRITY 1573
            +I+A   +G    P+ +    STVS   P +L + + TP SL +SW  P   V +Y +TY
Sbjct: 716  TILAYYRDGARSDPVSLRYTPSTVSRSPPSNLALASETPDSLQVSWTPPLGRVLHYWLTY 775

Query: 1574 GETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASS 1622
                G  P +  +VPG++S  T+  L+    Y + V A+   G S A S
Sbjct: 776  APASGLGPEKSVSVPGARSHVTLPDLQAATKYRVLVSAIYAAGRSEAVS 824



 Score =  115 bits (287), Expect = 7e-25
 Identities = 125/503 (24%), Positives = 208/503 (41%), Gaps = 40/503 (7%)

Query: 1615 RGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKWLPSSSPVTGYRVTTTPKNGPG 1674
            +G SP    P +      +  P+ + ++ V  +SI + W P+      Y +      G  
Sbjct: 360  QGGSPRQG-PAAAPALDTLPAPTSLVLSQVTSSSIRLSWTPAPRHPLKYLIVWRASRGGT 418

Query: 1675 PTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTN-IDRPKGLAFTD 1733
            P +    GP      +  L    EY+VSV+     G  + L     T  +  P+ L    
Sbjct: 419  PREVVVEGP-AASTELHNLASRTEYLVSVFPIYEGGVGEGLRGLVTTAPLPPPRALTLAA 477

Query: 1734 VDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQ---------GLR 1784
            V   ++ + W+ P    + Y V  S           +P GEE+  E+Q         GL 
Sbjct: 478  VTPRTVHLTWQ-PSAGATHYLVRCSPA---------SPKGEEEEREVQVGRPEVLLDGLE 527

Query: 1785 PGSEYTVSVVALHDDMESQPL-IGTQSTAIPAPTDLKFTQVTPTSLSAQW--TPPNVQLT 1841
            PG +Y VSV +L     S+   I  ++  +  P  L F+ V+  +    W   P  V+L 
Sbjct: 528  PGRDYEVSVQSLRGPEGSEARGIRARTPTLAPPRHLGFSDVSHDAARVFWEGAPRPVRL- 586

Query: 1842 GYRVRVTPKEKTGPMKEINLAP-DSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVT 1900
               VRVT     G       AP +++S  +  L  +T Y V V  L     S    G VT
Sbjct: 587  ---VRVTYVSSEGGHSGQTEAPGNATSATLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVT 643

Query: 1901 TLENVSPPRRARVTDATETTITISWRTKTET-ITGFQVDAVPANGQTPIQRTIKPDVRSY 1959
            T +  SP + + +T+     + ++W     + +  +Q+   P       + ++  ++ + 
Sbjct: 644  TKKAPSPSQLS-MTELPGDAVQLAWVAAAPSGVLVYQITWTPLGEGKAHEISVPGNLGTA 702

Query: 1960 TITGLQPGTDYKIYLYTL-NDNARSSPVVI---DASTAIDAPSNLRFLATTPNSLLVSWQ 2015
             + GL   T+Y + +     D ARS PV +    ++ +   PSNL   + TP+SL VSW 
Sbjct: 703  VLPGLGRHTEYDVTILAYYRDGARSDPVSLRYTPSTVSRSPPSNLALASETPDSLQVSWT 762

Query: 2016 PPRARITGYIIKY-EKPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKNNQKSE 2074
            PP  R+  Y + Y    G  P + V  P    +  T+  L+  T+Y + V A+    +SE
Sbjct: 763  PPLGRVLHYWLTYAPASGLGPEKSVSVP-GARSHVTLPDLQAATKYRVLVSAIYAAGRSE 821

Query: 2075 PL--IGRKKTVQKTPFVTHPGYD 2095
             +   G+       P  + PG+D
Sbjct: 822  AVSATGQTACPALRPDGSLPGFD 844



 Score =  102 bits (255), Expect = 3e-21
 Identities = 130/522 (24%), Positives = 196/522 (37%), Gaps = 52/522 (9%)

Query: 599  CQPLQTYPSSSGPVEVFITETPSQP----------NSHPIQWNAPQPSHISKYILRWRPK 648
            CQ LQ      GP      +T   P          +S  + W  P P H  KY++ WR  
Sbjct: 356  CQRLQGGSPRQGPAAAPALDTLPAPTSLVLSQVTSSSIRLSWT-PAPRHPLKYLIVWRAS 414

Query: 649  NSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTS 708
               G  +E  + G   S  +  L     Y   +  I + G  E  R    TT+   P   
Sbjct: 415  RG-GTPREVVVEGPAASTELHNLASRTEYLVSVFPIYEGGVGEGLR-GLVTTAPLPP--- 469

Query: 709  NTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDL 768
                       P   T  +VT  T     ++W   S   + + V    +    E +  ++
Sbjct: 470  -----------PRALTLAAVTPRTVH---LTW-QPSAGATHYLVRCSPASPKGEEEEREV 514

Query: 769  PSTATSVNIPDLLPGRKYIVNVYQI--SEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTS 826
                  V +  L PGR Y V+V  +   E  E   I + + T AP  P       V   +
Sbjct: 515  QVGRPEVLLDGLEPGRDYEVSVQSLRGPEGSEARGIRARTPTLAP--PRHLGFSDVSHDA 572

Query: 827  IVVRWSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEEN 886
              V W     P+   R+ Y  S  G S +   P  A S TL  L     Y + +  +   
Sbjct: 573  ARVFWEGAPRPVRLVRVTYVSSEGGHSGQTEAPGNATSATLGPLSSSTTYTVRVTCLYPG 632

Query: 887  QESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMW-TPPESAVTGYRVDVIPVN 945
              S+ +      TG   +   PSP  L   E+    V + W     S V  Y++   P+ 
Sbjct: 633  GGSSTL------TGRVTTKKAPSPSQLSMTELPGDAVQLAWVAAAPSGVLVYQITWTPLG 686

Query: 946  LPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFA-VSHGRESKPLTAQ---QTTKLDAPT 1001
                H   +P +  T A + GL     Y   + A    G  S P++ +    T     P+
Sbjct: 687  EGKAHEISVPGNLGT-AVLPGLGRHTEYDVTILAYYRDGARSDPVSLRYTPSTVSRSPPS 745

Query: 1002 NLQFVNETDSTVLVRWTPPRAQITGYRLTVG-LTRRGQPRQYNVGPSVSKYPLRNLQPAS 1060
            NL   +ET  ++ V WTPP  ++  Y LT    +  G  +  +V  + S   L +LQ A+
Sbjct: 746  NLALASETPDSLQVSWTPPLGRVLHYWLTYAPASGLGPEKSVSVPGARSHVTLPDLQAAT 805

Query: 1061 EYTVSLVAI--KGNQESPKATG--VFTTLQPGSSIPPYNTEV 1098
            +Y V + AI   G  E+  ATG      L+P  S+P ++  V
Sbjct: 806  KYRVLVSAIYAAGRSEAVSATGQTACPALRPDGSLPGFDLMV 847



 Score = 91.3 bits (225), Expect = 1e-17
 Identities = 111/478 (23%), Positives = 191/478 (39%), Gaps = 23/478 (4%)

Query: 895  QQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQRL 954
            +Q     P  DT+P+P  L   +VT   + + WTP       Y + V   +  G   + +
Sbjct: 365  RQGPAAAPALDTLPAPTSLVLSQVTSSSIRLSWTPAPRHPLKYLI-VWRASRGGTPREVV 423

Query: 955  PISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTT-KLDAPTNLQFVNETDSTV 1013
                    E+  L+    Y   VF +  G   + L    TT  L  P  L     T  TV
Sbjct: 424  VEGPAASTELHNLASRTEYLVSVFPIYEGGVGEGLRGLVTTAPLPPPRALTLAAVTPRTV 483

Query: 1014 LVRWTPPRAQITGYRLTVG-LTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGN 1072
             + W  P A  T Y +     + +G+  +  V     +  L  L+P  +Y VS+ +++G 
Sbjct: 484  HLTW-QPSAGATHYLVRCSPASPKGEEEEREVQVGRPEVLLDGLEPGRDYEVSVQSLRG- 541

Query: 1073 QESPKATGVFTTLQPGSSIPPYN---TEVTETTIVITWTPAPRIGFKLGVR--PSQGGEA 1127
             E  +A G+    +  +  PP +   ++V+     + W  APR    + V    S+GG +
Sbjct: 542  PEGSEARGI--RARTPTLAPPRHLGFSDVSHDAARVFWEGAPRPVRLVRVTYVSSEGGHS 599

Query: 1128 PR-EVTSDSGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSP-PTNLHLEAN 1185
             + E   ++ S  +  L+    Y   +  L  G    + +  +V T  +P P+ L +   
Sbjct: 600  GQTEAPGNATSATLGPLSSSTTYTVRVTCLYPG-GGSSTLTGRVTTKKAPSPSQLSMTEL 658

Query: 1186 PDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNV 1245
            P   V  ++W  +    +  Y+IT TP    +G + E  V  +  +     L    EY+V
Sbjct: 659  PGDAV-QLAWVAAAPSGVLVYQITWTPLG--EGKAHEISVPGNLGTAVLPGLGRHTEYDV 715

Query: 1246 SVYT-VKDDKESVPISDTIIPEVPQL---TDLSFVDITDSSIGLRWTPLNSSTIIGYRIT 1301
            ++    +D   S P+S    P        ++L+    T  S+ + WTP     ++ Y +T
Sbjct: 716  TILAYYRDGARSDPVSLRYTPSTVSRSPPSNLALASETPDSLQVSWTP-PLGRVLHYWLT 774

Query: 1302 VVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAVP 1359
               A    P     V  +  + T+  L+    Y + V  +   G S   + T QTA P
Sbjct: 775  YAPASGLGPEKSVSVPGARSHVTLPDLQAATKYRVLVSAIYAAGRSEAVSATGQTACP 832



 Score = 74.7 bits (182), Expect = 1e-12
 Identities = 92/414 (22%), Positives = 159/414 (38%), Gaps = 34/414 (8%)

Query: 590 YGRGIGEWHCQPLQTYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSH-ISKYILRWRPK 648
           Y  G+GE     + T P    P    +T     P +  + W   QPS   + Y++R  P 
Sbjct: 450 YEGGVGEGLRGLVTTAPL---PPPRALTLAAVTPRTVHLTW---QPSAGATHYLVRCSPA 503

Query: 649 NSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTS 708
           +  G  +E  +        + GL+PG  YE  + S++     E       T + + P   
Sbjct: 504 SPKGEEEEREVQVGRPEVLLDGLEPGRDYEVSVQSLRGPEGSEARGIRARTPTLAPP--- 560

Query: 709 NTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDL 768
                               ++++  +  V W  A   V   RV Y  SE G   Q  + 
Sbjct: 561 ---------------RHLGFSDVSHDAARVFWEGAPRPVRLVRVTYVSSEGGHSGQ-TEA 604

Query: 769 PSTATSVNIPDLLPGRKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIV 828
           P  ATS  +  L     Y V V  +   G  S +     T    +P   ++ ++   ++ 
Sbjct: 605 PGNATSATLGPLSSSTTYTVRVTCLYPGGGSSTLTGRVTTKKAPSPSQLSMTELPGDAVQ 664

Query: 829 VRW-SRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYA-VEEN 886
           + W +   + +  Y+I ++P  EG + E+++P    +  L  L    +Y++TI A   + 
Sbjct: 665 LAWVAAAPSGVLVYQITWTPLGEGKAHEISVPGNLGTAVLPGLGRHTEYDVTILAYYRDG 724

Query: 887 QESTPVVIQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIMWTPPESAVTGYRVDVIPVN- 945
             S PV ++     TP + +   P +L     T   + + WTPP   V  Y +   P + 
Sbjct: 725 ARSDPVSLRY----TPSTVSRSPPSNLALASETPDSLQVSWTPPLGRVLHYWLTYAPASG 780

Query: 946 LPGEHGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDA 999
           L  E    +P +R +   +  L     Y   V A+     S+ ++A   T   A
Sbjct: 781 LGPEKSVSVPGAR-SHVTLPDLQAATKYRVLVSAIYAAGRSEAVSATGQTACPA 833



 Score = 65.5 bits (158), Expect = 6e-10
 Identities = 66/271 (24%), Positives = 113/271 (41%), Gaps = 23/271 (8%)

Query: 604 TYPSSSGPVEVFITETPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHL 663
           T   +  P ++ +TE P   ++  + W A  PS +  Y + W P    G+  E ++PG+L
Sbjct: 643 TTKKAPSPSQLSMTELPG--DAVQLAWVAAAPSGVLVYQITWTPLGE-GKAHEISVPGNL 699

Query: 664 NSYTIKGLKPGVVYEGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVA 723
            +  + GL     Y+  +++  + G +        +   S   T +TV+   +P S L  
Sbjct: 700 GTAVLPGLGRHTEYDVTILAYYRDGAR--------SDPVSLRYTPSTVS--RSPPSNLAL 749

Query: 724 TSESVTEITASSFVVSWVSASDTVSGFRVEYELSEEGDEPQYLDLPSTATSVNIPDLLPG 783
            SE     T  S  VSW      V  + + Y  +      + + +P   + V +PDL   
Sbjct: 750 ASE-----TPDSLQVSWTPPLGRVLHYWLTYAPASGLGPEKSVSVPGARSHVTLPDLQAA 804

Query: 784 RKYIVNVYQISEDGEQSLILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQAPITGYR- 842
            KY V V  I   G    + +T QT  P   PD ++   D   ++V +S  +      R 
Sbjct: 805 TKYRVLVSAIYAAGRSEAVSATGQTACPALRPDGSLPGFD---LMVAFSLVEKAYASIRG 861

Query: 843 IVYSPSVEGSSTELNLPETAN-SVTLSDLQP 872
           +   PS  G +    L + A  +  +SD+ P
Sbjct: 862 VAMEPSAFGGTPTFTLFKDAQLTRRVSDVYP 892



 Score = 46.2 bits (108), Expect = 4e-04
 Identities = 54/239 (22%), Positives = 77/239 (32%), Gaps = 56/239 (23%)

Query: 1982 RSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQP-PRARITGYIIKYEKPGSPPREVVP 2040
            R  P    A   + AP++L     T +S+ +SW P PR  +   I+     G  PREVV 
Sbjct: 365  RQGPAAAPALDTLPAPTSLVLSQVTSSSIRLSWTPAPRHPLKYLIVWRASRGGTPREVVV 424

Query: 2041 RPRPGVTEATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKTVQKTPFVTHPGYDTGNGI 2100
                  TE  +  L   TEY + V                           P Y+ G G 
Sbjct: 425  EGPAASTE--LHNLASRTEYLVSVF--------------------------PIYEGGVGE 456

Query: 2101 QLPGTSGQQPSVGQQMIFEEHGFRRTTPPTTATPIRHRPRPYPPNVGQEALSQTTISWAP 2160
             L G     P                 PP   T     PR               ++W P
Sbjct: 457  GLRGLVTTAP---------------LPPPRALTLAAVTPRT------------VHLTWQP 489

Query: 2161 FQDTSEYIISCHPVGTDEEPLQFRVPGTSTSATLTGLTRGATYNIIVEALKDQQRHKVR 2219
                + Y++ C P     E  +  V        L GL  G  Y + V++L+  +  + R
Sbjct: 490  SAGATHYLVRCSPASPKGEEEEREVQVGRPEVLLDGLEPGRDYEVSVQSLRGPEGSEAR 548


>gi|18860892 protein tyrosine phosphatase, receptor type, D isoform 3
            precursor [Homo sapiens]
          Length = 1903

 Score =  149 bits (377), Expect = 2e-35
 Identities = 170/673 (25%), Positives = 286/673 (42%), Gaps = 81/673 (12%)

Query: 1458 SDITANSFTVHWIAPRAT-ITGYRIRHHPEHFSGRPRE-DRVPHSRNSITLTNLTPGTEY 1515
            ++ TA S T+ W +     ++ Y I+H P++     +E D V  +R S+    L+P ++Y
Sbjct: 332  TESTATSITLTWDSGNPEPVSYYIIQHKPKNSEELYKEIDGVATTRYSVA--GLSPYSDY 389

Query: 1516 VVSIVALN----GREESPLLIG-QQSTVSDVPRDLEVVAATPTSLLISW---DAPAVTVR 1567
               +VA+N    G    P+L    +   S  PRD++    + T++L+ W   + P   ++
Sbjct: 390  EFRVVAVNNIGRGPPSEPVLTQTSEQAPSSAPRDVQARMLSSTTILVQWKEPEEPNGQIQ 449

Query: 1568 YYRITY--GETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPI 1625
             YR+ Y    T   +   +  V  S+ T TI  L P   Y++ V A T  GD P SS   
Sbjct: 450  GYRVYYTMDPTQHVNNWMKHNVADSQIT-TIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQ 508

Query: 1626 SINYRTEIDKPSQMQVTDVQDNSISVKWL-PSSSPVTGYRVTTTPKNGPGPTKTKTAGPD 1684
             I       +P   +     + SI + W  P S  +  Y +    K+G    + +     
Sbjct: 509  VITQTGVPGQPLNFKAEPESETSILLSWTPPRSDTIANYELVY--KDGEHGEEQRITIEP 566

Query: 1685 QTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVTNIDR-----PKGLAFTDVDVDSI 1739
             T   ++GL+P   Y   + A++P G      + +   +       P+ ++ T     SI
Sbjct: 567  GTSYRLQGLKPNSLYYFRLAARSPQGLGASTAEISARTMQSKPSAPPQDISCTSPSSTSI 626

Query: 1740 KIAWESP-----QGQVSRYRVTYSS---PEDGIHELFPAPDGEEDTAE--LQGLRPGSEY 1789
             ++W+ P      G ++ Y + Y++    +D  HE+   P    DT +  L+ L   +EY
Sbjct: 627  LVSWQPPPVEKQNGIITEYSIKYTAVDGEDDKPHEILGIP---SDTTKYLLEQLEKWTEY 683

Query: 1790 TVSVVALHDDM----ESQPLIGTQSTAIPA--PTDLKFTQVTPTSLSAQWTPP-----NV 1838
             ++V A H D+    ES  ++   +  +P+  P  ++   V  TS+   W  P     + 
Sbjct: 684  RITVTA-HTDVGPGPESLSVLIRTNEDVPSGPPRKVEVEAVNSTSVKVSWRSPVPNKQHG 742

Query: 1839 QLTGYRVRVTPKEKTGP-----MKEINLAPDSSSVVVSGLMVATKYEVSVYALK---DTL 1890
            Q+ GY+V     E   P     +K++ LA D+  +++SGL   T Y ++V A     D  
Sbjct: 743  QIRGYQVHYVRMENGEPKGQPMLKDVMLA-DAQDMIISGLQPETSYSLTVTAYTTKGDGA 801

Query: 1891 TSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTET---ITGFQV-----DAVPA 1942
             S+P   +V+T   V    R  +      T  I W    +T   + G+++     D  P 
Sbjct: 802  RSKPK--LVSTTGAVPGKPRLVINHTQMNTALIQWHPPVDTFGPLQGYRLKFGRKDMEPL 859

Query: 1943 NGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPS---- 1998
               T ++ + K D   +T T +  G  Y   L   N       +V + S   + P+    
Sbjct: 860  ---TTLEFSEKED--HFTATDIHKGASYVFRLSARNKVGFGEEMVKEISIPEEVPTGFPQ 914

Query: 1999 NLRFLATTPNSLLVSWQPP-----RARITGYIIKYEKPGSPPREVVPRPRPGVTEATITG 2053
            NL    TT  S+ +SWQPP        IT Y + Y     P   +     P  T  T+TG
Sbjct: 915  NLHSEGTTSTSVQLSWQPPVLAERNGIITKYTLLYRDINIPLLPMEQLIVPADTTMTLTG 974

Query: 2054 LEPGTEYTIYVIA 2066
            L+P T Y + V A
Sbjct: 975  LKPDTTYDVKVRA 987



 Score =  146 bits (369), Expect = 2e-34
 Identities = 234/1018 (22%), Positives = 390/1018 (38%), Gaps = 123/1018 (12%)

Query: 930  PESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSP--GVTYYFKVFAVSHGRESK 987
            P+  +T ++ D +PV+    +G+     +   +E  G +P  G     +      G+   
Sbjct: 153  PDPEITWFK-DFLPVDTSNNNGR----IKQLRSESIGGTPIRGALQIEQSEESDQGKYEC 207

Query: 988  PLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQIT--------GYRLTVGLTRRGQP 1039
              T    T+  AP NL +V E      VR  PPR  I         G  + +     G P
Sbjct: 208  VATNSAGTRYSAPANL-YVRELRE---VRRVPPRFSIPPTNHEIMPGGSVNITCVAVGSP 263

Query: 1040 RQY----------------NVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFT 1083
              Y                 +G +V +  L +++ ++ YT   ++  G  E+     V  
Sbjct: 264  MPYVKWMLGAEDLTPEDDMPIGRNVLE--LNDVRQSANYTCVAMSTLGVIEAIAQITVKA 321

Query: 1084 TLQPGSSIPPYNTEVTETTIVITW---TPAPRIGFKLGVRPSQGGEAPREVTSDSGS-IV 1139
              +P  +  P  TE T T+I +TW    P P   + +  +P    E  +E+   + +   
Sbjct: 322  LPKPPGT--PVVTESTATSITLTWDSGNPEPVSYYIIQHKPKNSEELYKEIDGVATTRYS 379

Query: 1140 VSGLTPGVEYVYTIQVLRD---GQERDAPIVNKVV--TPLSPPTNLHLEANPDTGVLTVS 1194
            V+GL+P  +Y + +  + +   G   + P++ +     P S P ++       T +L V 
Sbjct: 380  VAGLSPYSDYEFRVVAVNNIGRGPPSE-PVLTQTSEQAPSSAPRDVQARMLSSTTIL-VQ 437

Query: 1195 WERSTTPD--ITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVY---T 1249
            W+    P+  I GYR+  T    Q  N+  +   AD    T  NL P   Y+V V    +
Sbjct: 438  WKEPEEPNGQIQGYRVYYTMDPTQHVNNWMKHNVADSQITTIGNLVPQKTYSVKVLAFTS 497

Query: 1250 VKDDKESVPISDTIIPEVP-QLTDLSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGEG 1308
            + D   S  I       VP Q  +      +++SI L WTP  S TI  Y +       G
Sbjct: 498  IGDGPLSSDIQVITQTGVPGQPLNFKAEPESETSILLSWTPPRSDTIANYELVYKDGEHG 557

Query: 1309 IPIFEDFVDSSVGY-YTVTGLEPGIDYDISVITLINGGESAPTT-----LTQQTAVPPPT 1362
                E  +    G  Y + GL+P   Y   +      G  A T        Q     PP 
Sbjct: 558  E---EQRITIEPGTSYRLQGLKPNSLYYFRLAARSPQGLGASTAEISARTMQSKPSAPPQ 614

Query: 1363 DLRFTNIGPDTMRVTWAPPPSID----LTNFLVRYSPVKNEEDVA-ELSISPSDNA-VVL 1416
            D+  T+    ++ V+W PPP       +T + ++Y+ V  E+D   E+   PSD    +L
Sbjct: 615  DISCTSPSSTSILVSWQPPPVEKQNGIITEYSIKYTAVDGEDDKPHEILGIPSDTTKYLL 674

Query: 1417 TNLLPGTEYVVSVSSVYE-----QHESTPLRGRQKTGLDSPTGIDFSDITANSFTVHWIA 1471
              L   TEY ++V++  +     +  S  +R  +      P  ++   + + S  V W +
Sbjct: 675  EQLEKWTEYRITVTAHTDVGPGPESLSVLIRTNEDVPSGPPRKVEVEAVNSTSVKVSWRS 734

Query: 1472 P-----RATITGYRIRHHPEHFSGRPR-----EDRVPHSRNSITLTNLTPGTEYVVSIVA 1521
            P        I GY++ H+    +G P+     +D +      + ++ L P T Y +++ A
Sbjct: 735  PVPNKQHGQIRGYQV-HYVRMENGEPKGQPMLKDVMLADAQDMIISGLQPETSYSLTVTA 793

Query: 1522 L----NGREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVT---VRYYRITYG 1574
                 +G    P L+     V   PR L +      + LI W  P  T   ++ YR+ +G
Sbjct: 794  YTTKGDGARSKPKLVSTTGAVPGKPR-LVINHTQMNTALIQWHPPVDTFGPLQGYRLKFG 852

Query: 1575 ETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEID 1634
                  P+        +   T + +  G  Y   + A    G      K ISI       
Sbjct: 853  RKD-MEPLTTLEFSEKEDHFTATDIHKGASYVFRLSARNKVGFGEEMVKEISIPEEVPTG 911

Query: 1635 KPSQMQVTDVQDNSISVKWLPS-----SSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMT 1689
             P  +        S+ + W P      +  +T Y +     N P     +   P  T MT
Sbjct: 912  FPQNLHSEGTTSTSVQLSWQPPVLAERNGIITKYTLLYRDINIPLLPMEQLIVPADTTMT 971

Query: 1690 IEGLQPTVEYVVSVYAQNPSGES--QPLVQTAVTNIDR--PKGLAFTDVDVDSIKIAWES 1745
            + GL+P   Y V V A    G     P VQ     +D+   K      V   S+ ++WE 
Sbjct: 972  LTGLKPDTTYDVKVRAHTSKGPGPYSPSVQFRTLPVDQVFAKNFHVKAVMKTSVLLSWEI 1031

Query: 1746 PQGQVSR--YRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHDDMESQ 1803
            P+   S   +++ Y   +DG  ++    DG      +  L+P   Y+     L +   S 
Sbjct: 1032 PENYNSAMPFKILY---DDG--KMVEEVDGRATQKLIVNLKPEKSYS---FVLTNRGNSA 1083

Query: 1804 PLIGTQSTAIPAPTDL--KFTQVTPTSLSAQWT------PPNVQLTGYRVRVTPKEKT 1853
              +  + TA  AP  L  K   +  T+L    T      P N  + GY + + P +K+
Sbjct: 1084 GGLQHRVTAKTAPDVLRTKPAFIGKTNLDGMITVQLPEVPANENIKGYYIIIVPLKKS 1141



 Score =  125 bits (314), Expect = 5e-28
 Identities = 161/700 (23%), Positives = 292/700 (41%), Gaps = 70/700 (10%)

Query: 696  DFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSAS-DTVSGFRVEY 754
            ++T  + ST      +   T    P    +  VTE TA+S  ++W S + + VS + +++
Sbjct: 299  NYTCVAMSTLGVIEAIAQITVKALPKPPGTPVVTESTATSITLTWDSGNPEPVSYYIIQH 358

Query: 755  ELSEEGDEPQYLDLPSTATS-VNIPDLLPGRKYIVNVYQISEDG----EQSLILSTSQTT 809
            +   +  E  Y ++   AT+  ++  L P   Y   V  ++  G     + ++  TS+  
Sbjct: 359  K--PKNSEELYKEIDGVATTRYSVAGLSPYSDYEFRVVAVNNIGRGPPSEPVLTQTSEQA 416

Query: 810  APDAPPDPTVDQVDDTSIVVRWSRPQAP---ITGYRIVYS--PSVEGSSTELNLPETANS 864
               AP D     +  T+I+V+W  P+ P   I GYR+ Y+  P+   ++   +    +  
Sbjct: 417  PSSAPRDVQARMLSSTTILVQWKEPEEPNGQIQGYRVYYTMDPTQHVNNWMKHNVADSQI 476

Query: 865  VTLSDLQPGVQYNITIYA---VEENQESTPV-VIQQETTGTPRSDTVPSPRDLQFVEVTD 920
             T+ +L P   Y++ + A   + +   S+ + VI Q  TG P       P + +    ++
Sbjct: 477  TTIGNLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQ--TGVP-----GQPLNFKAEPESE 529

Query: 921  VKVTIMWTPPES-AVTGYRVDVIPVNLPGEHG--QRLPISRNTFAEVTGLSPGVTYYFKV 977
              + + WTPP S  +  Y +    V   GEHG  QR+ I   T   + GL P   YYF++
Sbjct: 530  TSILLSWTPPRSDTIANYEL----VYKDGEHGEEQRITIEPGTSYRLQGLKPNSLYYFRL 585

Query: 978  FAVSH---GRESKPLTAQ--QTTKLDAPTNLQFVNETDSTVLVRWTPPRAQ-----ITGY 1027
             A S    G  +  ++A+  Q+     P ++   + + +++LV W PP  +     IT Y
Sbjct: 586  AARSPQGLGASTAEISARTMQSKPSAPPQDISCTSPSSTSILVSWQPPPVEKQNGIITEY 645

Query: 1028 --RLTVGLTRRGQPRQYNVGPS-VSKYPLRNLQPASEYTVSLVAIKGNQESPKATGV-FT 1083
              + T       +P +    PS  +KY L  L+  +EY +++ A       P++  V   
Sbjct: 646  SIKYTAVDGEDDKPHEILGIPSDTTKYLLEQLEKWTEYRITVTAHTDVGPGPESLSVLIR 705

Query: 1084 TLQPGSSIPPYNTE---VTETTIVITW-TPAPR------IGFKLGVRPSQGGEAPRE--- 1130
            T +   S PP   E   V  T++ ++W +P P        G+++     + GE   +   
Sbjct: 706  TNEDVPSGPPRKVEVEAVNSTSVKVSWRSPVPNKQHGQIRGYQVHYVRMENGEPKGQPML 765

Query: 1131 ---VTSDSGSIVVSGLTPGVEYVYTIQVLR---DGQERDAPIVNKVVTPLSPPTNLHLEA 1184
               + +D+  +++SGL P   Y  T+       DG      +V+        P  +    
Sbjct: 766  KDVMLADAQDMIISGLQPETSYSLTVTAYTTKGDGARSKPKLVSTTGAVPGKPRLVINHT 825

Query: 1185 NPDTGVLTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYN 1244
              +T ++       T   + GYR+     + +   +LE     D  + T  +      + 
Sbjct: 826  QMNTALIQWHPPVDTFGPLQGYRLKFGRKDMEPLTTLEFSEKEDHFTATDIHKGASYVFR 885

Query: 1245 VSVYTVKDDKESVPISDTIIPEVPQ--LTDLSFVDITDSSIGLRWTP--LNSSTIIGYRI 1300
            +S        E +    +I  EVP     +L     T +S+ L W P  L     I  + 
Sbjct: 886  LSARNKVGFGEEMVKEISIPEEVPTGFPQNLHSEGTTSTSVQLSWQPPVLAERNGIITKY 945

Query: 1301 TVVAAGEGIPI--FEDFVDSSVGYYTVTGLEPGIDYDISV 1338
            T++     IP+   E  +  +    T+TGL+P   YD+ V
Sbjct: 946  TLLYRDINIPLLPMEQLIVPADTTMTLTGLKPDTTYDVKV 985



 Score =  109 bits (272), Expect = 4e-23
 Identities = 185/811 (22%), Positives = 303/811 (37%), Gaps = 106/811 (13%)

Query: 619  TPSQPNSHPIQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNS-YTIKGLKPGVVY 677
            T S   S  + W++  P  +S YI++ +PKNS   +KE  I G   + Y++ GL P   Y
Sbjct: 332  TESTATSITLTWDSGNPEPVSYYIIQHKPKNSEELYKE--IDGVATTRYSVAGLSPYSDY 389

Query: 678  EGQLISIQQYGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFV 737
            E +++++   G              S PV   T T E  P S           +++++ +
Sbjct: 390  EFRVVAVNNIGR----------GPPSEPVL--TQTSEQAPSS--APRDVQARMLSSTTIL 435

Query: 738  VSWVSASD---TVSGFRVEYELSEEGDEPQYLDLPSTATSV-NIPDLLPGRKYIVNVYQI 793
            V W    +    + G+RV Y +        ++      + +  I +L+P + Y V V   
Sbjct: 436  VQWKEPEEPNGQIQGYRVYYTMDPTQHVNNWMKHNVADSQITTIGNLVPQKTYSVKVLAF 495

Query: 794  SEDGEQSL---ILSTSQTTAPDAPPDPTVDQVDDTSIVVRWSRPQA-PITGYRIVYSPSV 849
            +  G+  L   I   +QT  P  P +   +   +TSI++ W+ P++  I  Y +VY    
Sbjct: 496  TSIGDGPLSSDIQVITQTGVPGQPLNFKAEPESETSILLSWTPPRSDTIANYELVYKDGE 555

Query: 850  EGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVPS 909
             G    + + E   S  L  L+P   Y   + A   + +       + +  T +S     
Sbjct: 556  HGEEQRITI-EPGTSYRLQGLKPNSLYYFRLAA--RSPQGLGASTAEISARTMQSKPSAP 612

Query: 910  PRDLQFVEVTDVKVTIMWTPP-----ESAVTGYRVDVIPVNLPGEHGQRLPISRNTFAEV 964
            P+D+     +   + + W PP        +T Y +    V+  GE  +          E+
Sbjct: 613  PQDISCTSPSSTSILVSWQPPPVEKQNGIITEYSIKYTAVD--GEDDKP--------HEI 662

Query: 965  TGLSPGVTYY----------FKVFAVSH---GRESKPLTAQQTTKLDAPT------NLQF 1005
             G+    T Y          +++   +H   G   + L+    T  D P+       ++ 
Sbjct: 663  LGIPSDTTKYLLEQLEKWTEYRITVTAHTDVGPGPESLSVLIRTNEDVPSGPPRKVEVEA 722

Query: 1006 VNETDSTVLVRWTPP-----RAQITGYRLTVGLTRRGQPRQYNVGPSV-----SKYPLRN 1055
            VN T  +V V W  P       QI GY++       G+P+   +   V         +  
Sbjct: 723  VNST--SVKVSWRSPVPNKQHGQIRGYQVHYVRMENGEPKGQPMLKDVMLADAQDMIISG 780

Query: 1056 LQPASEY--TVSLVAIKGNQESPKATGVFTT-LQPGSSIPPYNTEVTETTIVITWTP--- 1109
            LQP + Y  TV+    KG+    K   V TT   PG      N      T +I W P   
Sbjct: 781  LQPETSYSLTVTAYTTKGDGARSKPKLVSTTGAVPGKPRLVIN-HTQMNTALIQWHPPVD 839

Query: 1110 --APRIGFKLGV-RPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTIQVLRD---GQERD 1163
               P  G++L   R         E +        + +  G  YV+ +        G+E  
Sbjct: 840  TFGPLQGYRLKFGRKDMEPLTTLEFSEKEDHFTATDIHKGASYVFRLSARNKVGFGEEMV 899

Query: 1164 APIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPD----ITGYRITTTPTNGQQGN 1219
              I      P   P NLH E    T V  +SW+     +    IT Y +     N     
Sbjct: 900  KEISIPEEVPTGFPQNLHSEGTTSTSV-QLSWQPPVLAERNGIITKYTLLYRDINIPLLP 958

Query: 1220 SLEEVVHADQSSCTFDNLSPGLEYNVSV--YTVKDDKESVPISDTIIPEVPQLTDLSF-- 1275
              + +V AD ++ T   L P   Y+V V  +T K      P        V Q+   +F  
Sbjct: 959  MEQLIVPAD-TTMTLTGLKPDTTYDVKVRAHTSKGPGPYSPSVQFRTLPVDQVFAKNFHV 1017

Query: 1276 VDITDSSIGLRW-TPLNSSTIIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDY 1334
              +  +S+ L W  P N ++ + ++I      +G  + E  VD       +  L+P   Y
Sbjct: 1018 KAVMKTSVLLSWEIPENYNSAMPFKILY---DDGKMVEE--VDGRATQKLIVNLKPEKSY 1072

Query: 1335 DISVITLINGGESAPTTLTQQTAVPPPTDLR 1365
                  L N G SA     + TA   P  LR
Sbjct: 1073 S---FVLTNRGNSAGGLQHRVTAKTAPDVLR 1100



 Score = 61.6 bits (148), Expect = 9e-09
 Identities = 86/394 (21%), Positives = 154/394 (39%), Gaps = 72/394 (18%)

Query: 1889 TLTSRPAQGVVTTLENVS------PPRRARVTDATETTITISWRT-KTETITGFQVDAVP 1941
            T  +    GV+  +  ++      PP    VT++T T+IT++W +   E ++ + +   P
Sbjct: 301  TCVAMSTLGVIEAIAQITVKALPKPPGTPVVTESTATSITLTWDSGNPEPVSYYIIQHKP 360

Query: 1942 ANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNAR---SSPVVIDAS--TAIDA 1996
             N +   +         Y++ GL P +DY+  +  +N+  R   S PV+   S      A
Sbjct: 361  KNSEELYKEIDGVATTRYSVAGLSPYSDYEFRVVAVNNIGRGPPSEPVLTQTSEQAPSSA 420

Query: 1997 PSNLRFLATTPNSLLVSW---QPPRARITGYIIKYEKPGSPPREVVPRPRPGVTEATIT- 2052
            P +++    +  ++LV W   + P  +I GY + Y     P + V    +  V ++ IT 
Sbjct: 421  PRDVQARMLSSTTILVQWKEPEEPNGQIQGYRVYYTM--DPTQHVNNWMKHNVADSQITT 478

Query: 2053 --GLEPGTEYTIYVIAL----------------KNNQKSEPLIGRKKTVQKTPFV---TH 2091
               L P   Y++ V+A                 +     +PL  + +   +T  +   T 
Sbjct: 479  IGNLVPQKTYSVKVLAFTSIGDGPLSSDIQVITQTGVPGQPLNFKAEPESETSILLSWTP 538

Query: 2092 PGYDTGNGIQL----------------PGTSGQQPSVGQQMIF-------EEHGFRRTTP 2128
            P  DT    +L                PGTS +   +    ++          G   +T 
Sbjct: 539  PRSDTIANYELVYKDGEHGEEQRITIEPGTSYRLQGLKPNSLYYFRLAARSPQGLGASTA 598

Query: 2129 PTTATPIRHRPRPYPPNVGQEALSQTTI--SWAP------FQDTSEYIISCHPV-GTDEE 2179
              +A  ++ +P   P ++   + S T+I  SW P          +EY I    V G D++
Sbjct: 599  EISARTMQSKPSAPPQDISCTSPSSTSILVSWQPPPVEKQNGIITEYSIKYTAVDGEDDK 658

Query: 2180 PLQ-FRVPGTSTSATLTGLTRGATYNIIVEALKD 2212
            P +   +P  +T   L  L +   Y I V A  D
Sbjct: 659  PHEILGIPSDTTKYLLEQLEKWTEYRITVTAHTD 692


>gi|20665034 tenascin XB isoform 2 [Homo sapiens]
          Length = 673

 Score =  148 bits (373), Expect = 7e-35
 Identities = 118/479 (24%), Positives = 203/479 (42%), Gaps = 31/479 (6%)

Query: 1651 VKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSG 1710
            + W  +  P   + V     NG  P      G DQ+++ I GL+P+  Y   +Y  +   
Sbjct: 3    LSWSVAQGPFDSFVVQYEDTNGQ-PQALLVDG-DQSKILISGLEPSTPYRFLLYGLHEGK 60

Query: 1711 ESQPLVQTAVTNI---------DRPK--GLAFTDVDVDSIKIAWESPQGQVSRYRVTYSS 1759
               PL     T +          RP+   L+ TDV   S+++ WE+P G    + + +  
Sbjct: 61   RLGPLSAEGTTGLAPAGQTSEESRPRLSQLSVTDVTTSSLRLNWEAPPGAFDSFLLRFGV 120

Query: 1760 PEDGIHELFPAP--------DGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQST 1811
            P     E  P P         G   +A L+ LR G+ Y++++  L    ++  + GT  T
Sbjct: 121  PSPSTLEPHPRPLLQRELMVPGTRHSAVLRDLRSGTLYSLTLYGLRGPHKADSIQGTART 180

Query: 1812 AIP---APTDLKFTQVTPTSLSAQWTPPNVQLTGYRVRVTPKEKTGPMKEINLAPDSSSV 1868
              P   +P DL+F+++  TS    W PP  +   ++V     +   P + + +   + + 
Sbjct: 181  LSPVLESPRDLQFSEIRETSAKVNWMPPPSRADSFKVSYQLADGGEP-QSVQVDGQARTQ 239

Query: 1869 VVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTK 1928
             + GL+   +YEV+V +++    S P  G +TT+ +   P + R  + TE    + W+  
Sbjct: 240  KLQGLIPGARYEVTVVSVRGFEESEPLTGFLTTVPD--GPTQLRALNLTEGFAVLHWKPP 297

Query: 1929 TETITGFQVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVI 1988
               +  + V  V A G  P+Q         Y +  L   T+Y   +  L     +SP  I
Sbjct: 298  QNPVDTYDVQ-VTAPGAPPLQAETPGSAVDYPLHDLVLHTNYTATVRGLRGPNLTSPASI 356

Query: 1989 DASTAIDAPSNLRFLATTPNSLLVSWQPPRARITGYIIKYEKPGSPPREVVPRPRPGVTE 2048
              +T ++AP +L     TP + L++W  P  R  GY++ +  PG   +E++     G+T 
Sbjct: 357  TFTTGLEAPRDLEAKEVTPRTALLTWTEPPVRPAGYLLSFHTPGGQNQEIL--LPGGITS 414

Query: 2049 ATITGLEPGTEYTIYVIALKNNQKSEPLIGRKKT-VQKTPFVTHPGYDTGNGIQLPGTS 2106
              + GL P T Y   + A+       P+     T   + PF    G +  NG     TS
Sbjct: 415  HQLLGLFPSTSYNARLQAMWGQSLLPPVSTSFTTGGLRIPFPRDCGEEMQNGAGASRTS 473



 Score =  129 bits (325), Expect = 3e-29
 Identities = 113/471 (23%), Positives = 197/471 (41%), Gaps = 39/471 (8%)

Query: 1374 MRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVSVSSVY 1433
            MR++W+        +F+V+Y     +     L +    + ++++ L P T Y   +  ++
Sbjct: 1    MRLSWSVAQG-PFDSFVVQYEDTNGQPQA--LLVDGDQSKILISGLEPSTPYRFLLYGLH 57

Query: 1434 EQHESTPLRGRQKTGLDSPTG------------IDFSDITANSFTVHWIAPRATITGYRI 1481
            E     PL     TGL +P G            +  +D+T +S  ++W AP      + +
Sbjct: 58   EGKRLGPLSAEGTTGL-APAGQTSEESRPRLSQLSVTDVTTSSLRLNWEAPPGAFDSFLL 116

Query: 1482 RH---HPEHFSGRP-----REDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIG 1533
            R     P      P     RE  VP +R+S  L +L  GT Y +++  L G  ++  + G
Sbjct: 117  RFGVPSPSTLEPHPRPLLQRELMVPGTRHSAVLRDLRSGTLYSLTLYGLRGPHKADSIQG 176

Query: 1534 QQSTVSDV---PRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGS 1590
               T+S V   PRDL+      TS  ++W  P      ++++Y    G  P Q   V G 
Sbjct: 177  TARTLSPVLESPRDLQFSEIRETSAKVNWMPPPSRADSFKVSYQLADGGEP-QSVQVDGQ 235

Query: 1591 KSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSIS 1650
              T  + GL PG  Y +TV +V G  +    S+P++    T  D P+Q++  ++ +    
Sbjct: 236  ARTQKLQGLIPGARYEVTVVSVRGFEE----SEPLTGFLTTVPDGPTQLRALNLTEGFAV 291

Query: 1651 VKWLPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSG 1710
            + W P  +PV  Y V  T    P P + +T G    +  +  L     Y  +V       
Sbjct: 292  LHWKPPQNPVDTYDVQVTAPGAP-PLQAETPG-SAVDYPLHDLVLHTNYTATVRGLRGPN 349

Query: 1711 ESQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPA 1770
             + P   T  T ++ P+ L   +V   +  + W  P  + + Y +++ +P     E+   
Sbjct: 350  LTSPASITFTTGLEAPRDLEAKEVTPRTALLTWTEPPVRPAGYLLSFHTPGGQNQEIL-- 407

Query: 1771 PDGEEDTAELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTA---IPAPTD 1818
              G   + +L GL P + Y   + A+       P+  + +T    IP P D
Sbjct: 408  LPGGITSHQLLGLFPSTSYNARLQAMWGQSLLPPVSTSFTTGGLRIPFPRD 458



 Score =  119 bits (297), Expect = 5e-26
 Identities = 108/455 (23%), Positives = 184/455 (40%), Gaps = 28/455 (6%)

Query: 1557 ISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAV-TGR 1615
            +SW         + + Y +T G    Q   V G +S   ISGL+P   Y   +Y +  G+
Sbjct: 3    LSWSVAQGPFDSFVVQYEDTNGQP--QALLVDGDQSKILISGLEPSTPYRFLLYGLHEGK 60

Query: 1616 GDSPASSKPIS----INYRTEIDKP--SQMQVTDVQDNSISVKWLPSSSPVTGYRV---- 1665
               P S++  +        +E  +P  SQ+ VTDV  +S+ + W         + +    
Sbjct: 61   RLGPLSAEGTTGLAPAGQTSEESRPRLSQLSVTDVTTSSLRLNWEAPPGAFDSFLLRFGV 120

Query: 1666 ----TTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGESQPLVQTAVT 1721
                T  P   P   +       +    +  L+    Y +++Y      ++  +  TA T
Sbjct: 121  PSPSTLEPHPRPLLQRELMVPGTRHSAVLRDLRSGTLYSLTLYGLRGPHKADSIQGTART 180

Query: 1722 ---NIDRPKGLAFTDVDVDSIKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTA 1778
                ++ P+ L F+++   S K+ W  P  +   ++V+Y   + G  +     DG+  T 
Sbjct: 181  LSPVLESPRDLQFSEIRETSAKVNWMPPPSRADSFKVSYQLADGGEPQSVQV-DGQARTQ 239

Query: 1779 ELQGLRPGSEYTVSVVALHDDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPPNV 1838
            +LQGL PG+ Y V+VV++    ES+PL G  +T    PT L+   +T       W PP  
Sbjct: 240  KLQGLIPGARYEVTVVSVRGFEESEPLTGFLTTVPDGPTQLRALNLTEGFAVLHWKPPQN 299

Query: 1839 QLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGV 1898
             +  Y V+VT      P  +      +    +  L++ T Y  +V  L+    + PA   
Sbjct: 300  PVDTYDVQVT--APGAPPLQAETPGSAVDYPLHDLVLHTNYTATVRGLRGPNLTSPASIT 357

Query: 1899 VTTLENVSPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKP-DVR 1957
             TT   +  PR     + T  T  ++W        G+ +      GQ   Q  + P  + 
Sbjct: 358  FTT--GLEAPRDLEAKEVTPRTALLTWTEPPVRPAGYLLSFHTPGGQN--QEILLPGGIT 413

Query: 1958 SYTITGLQPGTDYKIYLYTLNDNARSSPVVIDAST 1992
            S+ + GL P T Y   L  +   +   PV    +T
Sbjct: 414  SHQLLGLFPSTSYNARLQAMWGQSLLPPVSTSFTT 448



 Score =  117 bits (294), Expect = 1e-25
 Identities = 115/480 (23%), Positives = 197/480 (41%), Gaps = 57/480 (11%)

Query: 628  IQWNAPQPSHISKYILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQY 687
            + W+  Q      +++++   N  G+ +   + G  +   I GL+P   Y   L     Y
Sbjct: 3    LSWSVAQ-GPFDSFVVQYEDTN--GQPQALLVDGDQSKILISGLEPSTPYRFLL-----Y 54

Query: 688  GHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWVSASDTV 747
            G  E  R    +   +T +      G+T+  S    +  SVT++T SS  ++W +     
Sbjct: 55   GLHEGKRLGPLSAEGTTGLAP---AGQTSEESRPRLSQLSVTDVTTSSLRLNWEAPPGAF 111

Query: 748  SGFRVEYELSEEGD-EP-------QYLDLPSTATSVNIPDLLPGRKYIVNVYQISEDGEQ 799
              F + + +      EP       + L +P T  S  + DL  G  Y + +Y +    + 
Sbjct: 112  DSFLLRFGVPSPSTLEPHPRPLLQRELMVPGTRHSAVLRDLRSGTLYSLTLYGLRGPHKA 171

Query: 800  SLILSTSQTTAP--DAPPDPTVDQVDDTSIVVRWSRPQAPITGYRIVYSPSVEGSSTELN 857
              I  T++T +P  ++P D    ++ +TS  V W  P +    +++ Y  +  G    + 
Sbjct: 172  DSIQGTARTLSPVLESPRDLQFSEIRETSAKVNWMPPPSRADSFKVSYQLADGGEPQSVQ 231

Query: 858  LPETANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQETTGTPRSDTVP-SPRDLQFV 916
            +   A +  L  L PG +Y +T+ +V   +ES P+        T    TVP  P  L+ +
Sbjct: 232  VDGQARTQKLQGLIPGARYEVTVVSVRGFEESEPL--------TGFLTTVPDGPTQLRAL 283

Query: 917  EVTDVKVTIMWTPPESAVTGYRVDVIPVNLPGEHGQR-----------LPISRNTFAEVT 965
             +T+    + W PP++ V  Y V V     P    +            L +  N  A V 
Sbjct: 284  NLTEGFAVLHWKPPQNPVDTYDVQVTAPGAPPLQAETPGSAVDYPLHDLVLHTNYTATVR 343

Query: 966  GL-SPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPTNLQFVNETDSTVLVRWTPPRAQI 1024
            GL  P +T               P +   TT L+AP +L+    T  T L+ WT P  + 
Sbjct: 344  GLRGPNLT--------------SPASITFTTGLEAPRDLEAKEVTPRTALLTWTEPPVRP 389

Query: 1025 TGYRLTVGLTRRGQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTT 1084
             GY L+   T  GQ ++  +   ++ + L  L P++ Y   L A+ G    P  +  FTT
Sbjct: 390  AGYLLSFH-TPGGQNQEILLPGGITSHQLLGLFPSTSYNARLQAMWGQSLLPPVSTSFTT 448



 Score =  115 bits (287), Expect = 7e-25
 Identities = 99/406 (24%), Positives = 167/406 (41%), Gaps = 32/406 (7%)

Query: 1316 VDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAVPPP-----------TDL 1364
            VD       ++GLEP   Y   +  L  G    P +    T + P            + L
Sbjct: 31   VDGDQSKILISGLEPSTPYRFLLYGLHEGKRLGPLSAEGTTGLAPAGQTSEESRPRLSQL 90

Query: 1365 RFTNIGPDTMRVTWAPPPSIDLTNFLVRY---SPVKNEEDVA-----ELSISPSDNAVVL 1416
              T++   ++R+ W  PP     +FL+R+   SP   E         EL +  + ++ VL
Sbjct: 91   SVTDVTTSSLRLNWEAPPGA-FDSFLLRFGVPSPSTLEPHPRPLLQRELMVPGTRHSAVL 149

Query: 1417 TNLLPGTEYVVSVSSVYEQHESTPLRGRQKT---GLDSPTGIDFSDITANSFTVHWIAPR 1473
             +L  GT Y +++  +   H++  ++G  +T    L+SP  + FS+I   S  V+W+ P 
Sbjct: 150  RDLRSGTLYSLTLYGLRGPHKADSIQGTARTLSPVLESPRDLQFSEIRETSAKVNWMPPP 209

Query: 1474 ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIG 1533
            +    +++ +      G P+  +V     +  L  L PG  Y V++V++ G EES  L G
Sbjct: 210  SRADSFKVSYQLAD-GGEPQSVQVDGQARTQKLQGLIPGARYEVTVVSVRGFEESEPLTG 268

Query: 1534 QQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVRYYRITYGETGGNSPVQEFTVPGSKST 1593
              +TV D P  L  +  T    ++ W  P   V  Y +    T   +P  +   PGS   
Sbjct: 269  FLTTVPDGPTQLRALNLTEGFAVLHWKPPQNPVDTYDVQV--TAPGAPPLQAETPGSAVD 326

Query: 1594 ATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKW 1653
              +  L    +YT TV  + G    P  + P SI + T ++ P  ++  +V   +  + W
Sbjct: 327  YPLHDLVLHTNYTATVRGLRG----PNLTSPASITFTTGLEAPRDLEAKEVTPRTALLTW 382

Query: 1654 LPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEY 1699
                    GY ++     G         G   T   + GL P+  Y
Sbjct: 383  TEPPVRPAGYLLSFHTPGGQNQEILLPGG--ITSHQLLGLFPSTSY 426



 Score =  106 bits (264), Expect = 3e-22
 Identities = 83/358 (23%), Positives = 143/358 (39%), Gaps = 26/358 (7%)

Query: 1739 IKIAWESPQGQVSRYRVTYSSPEDGIHELFPAPDGEEDTAELQGLRPGSEYTVSVVALHD 1798
            ++++W   QG    + V Y         L    DG++    + GL P + Y   +  LH+
Sbjct: 1    MRLSWSVAQGPFDSFVVQYEDTNGQPQALLV--DGDQSKILISGLEPSTPYRFLLYGLHE 58

Query: 1799 DMESQPLIGTQSTAI-----------PAPTDLKFTQVTPTSLSAQWTPPNVQLTGYRVR- 1846
                 PL    +T +           P  + L  T VT +SL   W  P      + +R 
Sbjct: 59   GKRLGPLSAEGTTGLAPAGQTSEESRPRLSQLSVTDVTTSSLRLNWEAPPGAFDSFLLRF 118

Query: 1847 -------VTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVV 1899
                   + P  +    +E+ +     S V+  L   T Y +++Y L+    +   QG  
Sbjct: 119  GVPSPSTLEPHPRPLLQRELMVPGTRHSAVLRDLRSGTLYSLTLYGLRGPHKADSIQGTA 178

Query: 1900 TTLENV-SPPRRARVTDATETTITISWRTKTETITGFQVDAVPANGQTPIQRTIKPDVRS 1958
             TL  V   PR  + ++  ET+  ++W         F+V    A+G  P    +    R+
Sbjct: 179  RTLSPVLESPRDLQFSEIRETSAKVNWMPPPSRADSFKVSYQLADGGEPQSVQVDGQART 238

Query: 1959 YTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPR 2018
              + GL PG  Y++ + ++     S P+    +T  D P+ LR L  T    ++ W+PP+
Sbjct: 239  QKLQGLIPGARYEVTVVSVRGFEESEPLTGFLTTVPDGPTQLRALNLTEGFAVLHWKPPQ 298

Query: 2019 ARITGYIIKYEKPGSPPREVVPRPRPG-VTEATITGLEPGTEYTIYVIALKNNQKSEP 2075
              +  Y ++   PG+PP +      PG   +  +  L   T YT  V  L+    + P
Sbjct: 299  NPVDTYDVQVTAPGAPPLQA---ETPGSAVDYPLHDLVLHTNYTATVRGLRGPNLTSP 353



 Score = 95.9 bits (237), Expect = 4e-19
 Identities = 105/452 (23%), Positives = 183/452 (40%), Gaps = 35/452 (7%)

Query: 831  WSRPQAPITGYRIVYSPSVEGSSTELNLPETANSVTLSDLQPGVQYNITIYAVEENQEST 890
            WS  Q P   + + Y  +  G    L +    + + +S L+P   Y   +Y + E +   
Sbjct: 5    WSVAQGPFDSFVVQYEDT-NGQPQALLVDGDQSKILISGLEPSTPYRFLLYGLHEGKRLG 63

Query: 891  PVVIQQETTGTPRSDTVPSPR----DLQFVEVTDVKVTIMWTPPESAVTGY--RVDVIPV 944
            P+  +  T   P   T    R     L   +VT   + + W  P  A   +  R  V   
Sbjct: 64   PLSAEGTTGLAPAGQTSEESRPRLSQLSVTDVTTSSLRLNWEAPPGAFDSFLLRFGVPSP 123

Query: 945  NLPGEHGQRL-------PISRNTFAEVTGLSPGVTYYFKVFAVS--HGRESKPLTAQQTT 995
            +    H + L       P +R++ A +  L  G  Y   ++ +   H  +S   TA+  +
Sbjct: 124  STLEPHPRPLLQRELMVPGTRHS-AVLRDLRSGTLYSLTLYGLRGPHKADSIQGTARTLS 182

Query: 996  K-LDAPTNLQFVNETDSTVLVRWTPPRAQITGYRLTVGLTRRGQPRQYNVGPSVSKYPLR 1054
              L++P +LQF    +++  V W PP ++   ++++  L   G+P+   V        L+
Sbjct: 183  PVLESPRDLQFSEIRETSAKVNWMPPPSRADSFKVSYQLADGGEPQSVQVDGQARTQKLQ 242

Query: 1055 NLQPASEYTVSLVAIKGNQESPKATGVFTTLQPG-SSIPPYNTEVTETTIVITWTPAPRI 1113
             L P + Y V++V+++G +ES   TG  TT+  G + +   N  +TE   V+ W P    
Sbjct: 243  GLIPGARYEVTVVSVRGFEESEPLTGFLTTVPDGPTQLRALN--LTEGFAVLHWKPPQNP 300

Query: 1114 GFKLGVRPSQGGEAPREVTSDSGSI--VVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVV 1171
                 V+ +  G  P +  +   ++   +  L     Y  T++ LR G    +P      
Sbjct: 301  VDTYDVQVTAPGAPPLQAETPGSAVDYPLHDLVLHTNYTATVRGLR-GPNLTSPASITFT 359

Query: 1172 TPLSPPTNLHL-EANPDTGVLTVSWERSTTPDI--TGYRITTTPTNGQQGNSLEEVVHAD 1228
            T L  P +L   E  P T +LT  W   T P +   GY ++     GQ   + E ++   
Sbjct: 360  TGLEAPRDLEAKEVTPRTALLT--W---TEPPVRPAGYLLSFHTPGGQ---NQEILLPGG 411

Query: 1229 QSSCTFDNLSPGLEYNVSVYTVKDDKESVPIS 1260
             +S     L P   YN  +  +       P+S
Sbjct: 412  ITSHQLLGLFPSTSYNARLQAMWGQSLLPPVS 443



 Score = 75.1 bits (183), Expect = 8e-13
 Identities = 101/440 (22%), Positives = 172/440 (39%), Gaps = 42/440 (9%)

Query: 1037 GQPRQYNVGPSVSKYPLRNLQPASEYTVSLVAI-KGNQESPKATGVFTTLQPGSSIPPYN 1095
            GQP+   V    SK  +  L+P++ Y   L  + +G +  P +    T L P       +
Sbjct: 24   GQPQALLVDGDQSKILISGLEPSTPYRFLLYGLHEGKRLGPLSAEGTTGLAPAGQTSEES 83

Query: 1096 ---------TEVTETTIVITWTPAP----RIGFKLGV-RPSQGGEAPRE-------VTSD 1134
                     T+VT +++ + W   P        + GV  PS     PR        V   
Sbjct: 84   RPRLSQLSVTDVTTSSLRLNWEAPPGAFDSFLLRFGVPSPSTLEPHPRPLLQRELMVPGT 143

Query: 1135 SGSIVVSGLTPGVEYVYTIQVLRDGQERDAPIVNKVVTPLSP----PTNLHLEANPDTGV 1190
              S V+  L  G  Y  T+  LR   + D+  +      LSP    P +L      +T  
Sbjct: 144  RHSAVLRDLRSGTLYSLTLYGLRGPHKADS--IQGTARTLSPVLESPRDLQFSEIRETSA 201

Query: 1191 LTVSWERSTTPDITGYRITTTPTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTV 1250
              V+W    +     ++++    +G +  S++  V     +     L PG  Y V+V +V
Sbjct: 202  -KVNWMPPPSR-ADSFKVSYQLADGGEPQSVQ--VDGQARTQKLQGLIPGARYEVTVVSV 257

Query: 1251 KDDKESVPISD--TIIPEVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGEG 1308
            +  +ES P++   T +P+ P  T L  +++T+    L W P   + +  Y + V A G  
Sbjct: 258  RGFEESEPLTGFLTTVPDGP--TQLRALNLTEGFAVLHWKP-PQNPVDTYDVQVTAPGA- 313

Query: 1309 IPIFEDFVDSSVGYYTVTGLEPGIDYDISVITLINGGESAPTTLTQQTAVPPPTDLRFTN 1368
             P  +     S   Y +  L    +Y  +V  L     ++P ++T  T +  P DL    
Sbjct: 314  -PPLQAETPGSAVDYPLHDLVLHTNYTATVRGLRGPNLTSPASITFTTGLEAPRDLEAKE 372

Query: 1369 IGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLTNLLPGTEYVVS 1428
            + P T  +TW  PP       L  ++P    +   E+ +     +  L  L P T Y   
Sbjct: 373  VTPRTALLTWTEPPVRPAGYLLSFHTPGGQNQ---EILLPGGITSHQLLGLFPSTSYNAR 429

Query: 1429 VSSVYEQHESTPLRGRQKTG 1448
            + +++ Q    P+     TG
Sbjct: 430  LQAMWGQSLLPPVSTSFTTG 449


>gi|109633041 protein tyrosine phosphatase, receptor type, F isoform 1
            precursor [Homo sapiens]
          Length = 1907

 Score =  147 bits (371), Expect = 1e-34
 Identities = 173/640 (27%), Positives = 262/640 (40%), Gaps = 80/640 (12%)

Query: 1493 REDRVPHSRNSITLTNLTPGTEYVVSIVALNGREESPLLIGQQSTVSDVPR---DLEVVA 1549
            +ED +P  RN + L+N+     Y    ++  G  E+      Q TV  +P+   DL V  
Sbjct: 274  KEDEMPVGRNVLELSNVVRSANYTCVAISSLGMIEATA----QVTVKALPKPPIDLVVTE 329

Query: 1550 ATPTSLLISWDAP-AVTVRYYRITYGETGGNSPVQEFTVPGSKSTA-TISGLKPGVDYTI 1607
             T TS+ ++WD+  +  V YY I Y   G   P QE  V G  +T  +I GL P  +Y  
Sbjct: 330  TTATSVTLTWDSGNSEPVTYYGIQYRAAGTEGPFQE--VDGVATTRYSIGGLSPFSEYAF 387

Query: 1608 TVYAVTGRGDSPASSKPISINYRTEIDKPS----QMQVTDVQDNSISVKWLPSSSP---V 1660
             V AV   G  P S    ++  RT    PS    ++Q   +  +++ V+W P   P   V
Sbjct: 388  RVLAVNSIGRGPPSE---AVRARTGEQAPSSPPRRVQARMLSASTMLVQWEPPEEPNGLV 444

Query: 1661 TGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEG-LQPTVEYVVSVYAQNPSGESQPLVQTA 1719
             GYRV  TP +   P        D   +T  G L P + Y + V A    G+  P     
Sbjct: 445  RGYRVYYTPDSRRPPNAWHKHNTDAGLLTTVGSLLPGITYSLRVLAFTAVGDGPPSPTIQ 504

Query: 1720 V-TNIDRPKGLAFTDVDVDS---IKIAWE-SPQGQVSRYRVTY--SSPEDGIHELFPAPD 1772
            V T    P   A    +V+S   I+++W   PQ ++  Y + Y  +  ED  H++   P 
Sbjct: 505  VKTQQGVPAQPADFQAEVESDTRIQLSWLLPPQERIIMYELVYWAAEDEDQQHKVTFDPT 564

Query: 1773 GEEDTAELQGLRPGSEYTVSVVALHD--------DMESQPLIGTQSTAIPAPTDLKFTQV 1824
                +  L+ L+P + Y   + A  D         +E++     QST    P  +    +
Sbjct: 565  S---SYTLEDLKPDTLYRFQLAARSDMGVGVFTPTIEART---AQSTPSAPPQKVMCVSM 618

Query: 1825 TPTSLSAQWTPP-----NVQLTGYRV--RVTPKEKTGPMKEINLAPDSSSVVVSGLMVAT 1877
              T++   W PP     N  +T Y V       E  G      ++ + SS  + GL   T
Sbjct: 619  GSTTVRVSWVPPPADSRNGVITQYSVAYEAVDGEDRGRHVVDGISREHSSWDLVGLEKWT 678

Query: 1878 KYEVSVYALKDTLTSRPAQGV-VTTLENV--SPPRRARVTDATETTITISWRTKTET--- 1931
            +Y V V A  D      +  V V T E+V   PPR+  V     T + + W+    +   
Sbjct: 679  EYRVWVRAHTDVGPGPESSPVLVRTDEDVPSGPPRKVEVEPLNSTAVHVYWKLPVPSKQH 738

Query: 1932 --ITGFQVDAVPANGQTPIQRTIKPDVR--------------SYTITGLQPGTDYKIYLY 1975
              I G+QV  V      P    I  DV                 TI+GL P T Y + + 
Sbjct: 739  GQIRGYQVTYVRLENGEPRGLPIIQDVMLAEAQWRPEESEDYETTISGLTPETTYSVTVA 798

Query: 1976 ---TLNDNARSSPVVIDASTAIDAPSNLRFLATTPNSLLVSWQPPR---ARITGYIIKYE 2029
               T  D ARS P ++  + A+     +    T  N+ L+ W PP+     + GY ++Y 
Sbjct: 799  AYTTKGDGARSKPKIVTTTGAVPGRPTMMISTTAMNTALLQWHPPKELPGELLGYRLQYC 858

Query: 2030 KPGSPPREVVPRPRPGVTEATITGLEPGTEYTIYVIALKN 2069
            +        +   +      T+TGL  GT Y I+ +A KN
Sbjct: 859  RADEARPNTIDFGKDD-QHFTVTGLHKGTTY-IFRLAAKN 896



 Score =  141 bits (355), Expect = 9e-33
 Identities = 169/737 (22%), Positives = 290/737 (39%), Gaps = 77/737 (10%)

Query: 1348 APTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAPPPSIDLTNFLVRYSPVKNEEDVAELSI 1407
            A   +T +    PP DL  T     ++ +TW    S  +T + ++Y     E    E+  
Sbjct: 309  ATAQVTVKALPKPPIDLVVTETTATSVTLTWDSGNSEPVTYYGIQYRAAGTEGPFQEVD- 367

Query: 1408 SPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRG-RQKTGLDSPTG----IDFSDITA 1462
              +     +  L P +EY   V +V       P    R +TG  +P+     +    ++A
Sbjct: 368  GVATTRYSIGGLSPFSEYAFRVLAVNSIGRGPPSEAVRARTGEQAPSSPPRRVQARMLSA 427

Query: 1463 NSFTVHWIAPR---ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLT---NLTPGTEYV 1516
            ++  V W  P      + GYR+ + P+  S RP      H+ ++  LT   +L PG  Y 
Sbjct: 428  STMLVQWEPPEEPNGLVRGYRVYYTPD--SRRPPNAWHKHNTDAGLLTTVGSLLPGITYS 485

Query: 1517 VSIVALNGREESP----LLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVT-VRYYRI 1571
            + ++A     + P    + +  Q  V   P D +    + T + +SW  P    +  Y +
Sbjct: 486  LRVLAFTAVGDGPPSPTIQVKTQQGVPAQPADFQAEVESDTRIQLSWLLPPQERIIMYEL 545

Query: 1572 TYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRT 1631
             Y          + T   + S+ T+  LKP   Y    + +  R D        +I  RT
Sbjct: 546  VYWAAEDEDQQHKVTFDPT-SSYTLEDLKPDTLYR---FQLAARSDMGVGVFTPTIEART 601

Query: 1632 EIDKPS----QMQVTDVQDNSISVKWLPSSSP-----VTGYRVTTTPKNGPGPTKTKTAG 1682
                PS    ++    +   ++ V W+P  +      +T Y V     +G    +    G
Sbjct: 602  AQSTPSAPPQKVMCVSMGSTTVRVSWVPPPADSRNGVITQYSVAYEAVDGEDRGRHVVDG 661

Query: 1683 --PDQTEMTIEGLQPTVEYVVSVYAQN---PSGESQPLVQTAVTNIDR--PKGLAFTDVD 1735
               + +   + GL+   EY V V A     P  ES P++     ++    P+ +    ++
Sbjct: 662  ISREHSSWDLVGLEKWTEYRVWVRAHTDVGPGPESSPVLVRTDEDVPSGPPRKVEVEPLN 721

Query: 1736 VDSIKIAWESP-----QGQVSRYRVTYSSPEDGIHELFPA------------PDGEED-T 1777
              ++ + W+ P      GQ+  Y+VTY   E+G     P             P+  ED  
Sbjct: 722  STAVHVYWKLPVPSKQHGQIRGYQVTYVRLENGEPRGLPIIQDVMLAEAQWRPEESEDYE 781

Query: 1778 AELQGLRPGSEYTVSVVALH---DDMESQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWT 1834
              + GL P + Y+V+V A     D   S+P I T + A+P    +  +     +   QW 
Sbjct: 782  TTISGLTPETTYSVTVAAYTTKGDGARSKPKIVTTTGAVPGRPTMMISTTAMNTALLQWH 841

Query: 1835 PPNV---QLTGYRVRVTPKEKTGPMKEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLT 1891
            PP     +L GYR++    ++  P   I+   D     V+GL   T Y   + A      
Sbjct: 842  PPKELPGELLGYRLQYCRADEARP-NTIDFGKDDQHFTVTGLHKGTTYIFRLAAKNRAGL 900

Query: 1892 SRPAQGVVTTLENVSP--PRRARVTDATETTITISW-----RTKTETITGFQVDAVPANG 1944
                +  + T E++    P+   VT  T +T  ++W       +   I  + V     N 
Sbjct: 901  GEEFEKEIRTPEDLPSGFPQNLHVTGLTTSTTELAWDPPVLAERNGRIISYTVVFRDINS 960

Query: 1945 QTPIQRTIKPDVRSYTITGLQPGTDY--KIYLYTLNDNARSSPVVIDASTAIDA--PSNL 2000
            Q  +Q  I  D R +T+TGL+P T Y  K+  +T   +   SP +   +  ++     N 
Sbjct: 961  QQELQN-ITTDTR-FTLTGLKPDTTYDIKVRAWTSKGSGPLSPSIQSRTMPVEQVFAKNF 1018

Query: 2001 RFLATTPNSLLVSWQPP 2017
            R  A    S+L+SW+ P
Sbjct: 1019 RVAAAMKTSVLLSWEVP 1035



 Score =  127 bits (320), Expect = 1e-28
 Identities = 178/740 (24%), Positives = 294/740 (39%), Gaps = 91/740 (12%)

Query: 1399 EEDVAELSISPSDNAVVLTNLLPGTEYV-VSVSSV--YEQHESTPLRGRQKTGLDSPTGI 1455
            EE   E  +    N + L+N++    Y  V++SS+   E      ++   K  +D    +
Sbjct: 270  EELTKEDEMPVGRNVLELSNVVRSANYTCVAISSLGMIEATAQVTVKALPKPPID----L 325

Query: 1456 DFSDITANSFTVHWIAPRAT-ITGYRIRHHPEHFSGRPRE-DRVPHSRNSITLTNLTPGT 1513
              ++ TA S T+ W +  +  +T Y I++      G  +E D V  +R SI    L+P +
Sbjct: 326  VVTETTATSVTLTWDSGNSEPVTYYGIQYRAAGTEGPFQEVDGVATTRYSIG--GLSPFS 383

Query: 1514 EYVVSIVALNGREESP------LLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVT-- 1565
            EY   ++A+N     P         G+Q+  S  PR ++    + +++L+ W+ P     
Sbjct: 384  EYAFRVLAVNSIGRGPPSEAVRARTGEQAP-SSPPRRVQARMLSASTMLVQWEPPEEPNG 442

Query: 1566 -VRYYRITYGETGGNSPV---QEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPAS 1621
             VR YR+ Y       P    +  T  G  +T  +  L PG+ Y++ V A T  GD P S
Sbjct: 443  LVRGYRVYYTPDSRRPPNAWHKHNTDAGLLTT--VGSLLPGITYSLRVLAFTAVGDGPPS 500

Query: 1622 SKPISINYRTEIDKPSQ---MQVTDVQDNSISVKWL-PSSSPVTGYRVTTTPKNGPGPTK 1677
                +I  +T+   P+Q    Q     D  I + WL P    +  Y +            
Sbjct: 501  P---TIQVKTQQGVPAQPADFQAEVESDTRIQLSWLLPPQERIIMYELVYWAAEDEDQQH 557

Query: 1678 TKTAGPDQTEMTIEGLQPTVEYVVSVYAQNPSGES--QPLVQTAV---TNIDRPKGLAFT 1732
              T  P  +  T+E L+P   Y   + A++  G     P ++      T    P+ +   
Sbjct: 558  KVTFDPTSS-YTLEDLKPDTLYRFQLAARSDMGVGVFTPTIEARTAQSTPSAPPQKVMCV 616

Query: 1733 DVDVDSIKIAWESP-----QGQVSRYRVTYSSP--EDGIHELFPAPDGEEDTAELQGLRP 1785
             +   +++++W  P      G +++Y V Y +   ED    +      E  + +L GL  
Sbjct: 617  SMGSTTVRVSWVPPPADSRNGVITQYSVAYEAVDGEDRGRHVVDGISREHSSWDLVGLEK 676

Query: 1786 GSEYTVSVVALHDDM----ESQPLIGTQSTAIPA--PTDLKFTQVTPTSLSAQWTPP--- 1836
             +EY V V A H D+    ES P++      +P+  P  ++   +  T++   W  P   
Sbjct: 677  WTEYRVWVRA-HTDVGPGPESSPVLVRTDEDVPSGPPRKVEVEPLNSTAVHVYWKLPVPS 735

Query: 1837 --NVQLTGYRVRVTPKEKTGP----------MKEINLAPDSSS---VVVSGLMVATKYEV 1881
              + Q+ GY+V     E   P          + E    P+ S      +SGL   T Y V
Sbjct: 736  KQHGQIRGYQVTYVRLENGEPRGLPIIQDVMLAEAQWRPEESEDYETTISGLTPETTYSV 795

Query: 1882 SVYALK---DTLTSRPAQGVVTTLENVSPPRRARVTDATETTITISWRTKTET---ITGF 1935
            +V A     D   S+P   +VTT   V       ++     T  + W    E    + G+
Sbjct: 796  TVAAYTTKGDGARSKPK--IVTTTGAVPGRPTMMISTTAMNTALLQWHPPKELPGELLGY 853

Query: 1936 QVDAVPANGQTPIQRTIKPDVRSYTITGLQPGTDYKIYLYTLNDNARSSPVVIDASTAID 1995
            ++    A+   P       D + +T+TGL  GT Y   L   N          +  T  D
Sbjct: 854  RLQYCRADEARPNTIDFGKDDQHFTVTGLHKGTTYIFRLAAKNRAGLGEEFEKEIRTPED 913

Query: 1996 APS----NLRFLATTPNSLLVSWQPP-----RARITGYIIKYEKPGSPPREVVPRPRPGV 2046
             PS    NL     T ++  ++W PP       RI  Y + +    S   +   +     
Sbjct: 914  LPSGFPQNLHVTGLTTSTTELAWDPPVLAERNGRIISYTVVFRDINS---QQELQNITTD 970

Query: 2047 TEATITGLEPGTEYTIYVIA 2066
            T  T+TGL+P T Y I V A
Sbjct: 971  TRFTLTGLKPDTTYDIKVRA 990



 Score =  124 bits (312), Expect = 9e-28
 Identities = 198/846 (23%), Positives = 332/846 (39%), Gaps = 89/846 (10%)

Query: 862  ANSVTLSDLQPGVQYNITIYAVEENQESTPVVIQQ----ETTGTPRSDTVPSPR-DLQFV 916
            A  +T  D  P  +  + +  V  +   T V I      E T       +P P  DL   
Sbjct: 269  AEELTKEDEMPVGRNVLELSNVVRSANYTCVAISSLGMIEATAQVTVKALPKPPIDLVVT 328

Query: 917  EVTDVKVTIMWTPPESA-VTGYRVDVIPVNLPGEHGQRLPISRNTFAEVTGLSPGVTYYF 975
            E T   VT+ W    S  VT Y +        G   Q +     T   + GLSP   Y F
Sbjct: 329  ETTATSVTLTWDSGNSEPVTYYGIQYRAAGTEGPF-QEVDGVATTRYSIGGLSPFSEYAF 387

Query: 976  KVFAVS---HGRESKPLTAQ--QTTKLDAPTNLQFVNETDSTVLVRWTP---PRAQITGY 1027
            +V AV+    G  S+ + A+  +      P  +Q    + ST+LV+W P   P   + GY
Sbjct: 388  RVLAVNSIGRGPPSEAVRARTGEQAPSSPPRRVQARMLSASTMLVQWEPPEEPNGLVRGY 447

Query: 1028 RLTVGLTRRGQP---RQYNVGPSVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGVFTT 1084
            R+      R  P    ++N    +    + +L P   Y++ ++A     + P +  +   
Sbjct: 448  RVYYTPDSRRPPNAWHKHNTDAGLLT-TVGSLLPGITYSLRVLAFTAVGDGPPSPTIQVK 506

Query: 1085 LQPGSSIPP--YNTEV-TETTIVITWTPAPR---IGFKLGVRPSQGGEAPREVTSD-SGS 1137
             Q G    P  +  EV ++T I ++W   P+   I ++L    ++  +   +VT D + S
Sbjct: 507  TQQGVPAQPADFQAEVESDTRIQLSWLLPPQERIIMYELVYWAAEDEDQQHKVTFDPTSS 566

Query: 1138 IVVSGLTPGVEYVYTIQVLRD-GQERDAPIVNKVV---TPLSPPTNLHLEANPDTGVLTV 1193
              +  L P   Y + +    D G     P +       TP +PP  +   +   T V  V
Sbjct: 567  YTLEDLKPDTLYRFQLAARSDMGVGVFTPTIEARTAQSTPSAPPQKVMCVSMGSTTV-RV 625

Query: 1194 SW----ERSTTPDITGYRITTTPTNGQ-QGNSLEEVVHADQSSCTFDNLSPGLEYNVSVY 1248
            SW      S    IT Y +     +G+ +G  + + +  + SS     L    EY V V 
Sbjct: 626  SWVPPPADSRNGVITQYSVAYEAVDGEDRGRHVVDGISREHSSWDLVGLEKWTEYRVWVR 685

Query: 1249 TVKD---DKESVPI---SDTIIPEVPQLTDLSFVDITDSSIGLRW-TPLNS---STIIGY 1298
               D     ES P+   +D  +P  P    +    +  +++ + W  P+ S     I GY
Sbjct: 686  AHTDVGPGPESSPVLVRTDEDVPSGPP-RKVEVEPLNSTAVHVYWKLPVPSKQHGQIRGY 744

Query: 1299 RITVVAA--GE--GIPIFEDFV--------DSSVGY-YTVTGLEPGIDYDISV---ITLI 1342
            ++T V    GE  G+PI +D +        + S  Y  T++GL P   Y ++V    T  
Sbjct: 745  QVTYVRLENGEPRGLPIIQDVMLAEAQWRPEESEDYETTISGLTPETTYSVTVAAYTTKG 804

Query: 1343 NGGESAPTTLTQQTAVPPPTDLRFTNIGPDTMRVTWAPPPSI--DLTNFLVRYSPVKNEE 1400
            +G  S P  +T   AVP    +  +    +T  + W PP  +  +L  + ++Y    +E 
Sbjct: 805  DGARSKPKIVTTTGAVPGRPTMMISTTAMNTALLQWHPPKELPGELLGYRLQYCRA-DEA 863

Query: 1401 DVAELSISPSDNAVVLTNLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTG----ID 1456
                +     D    +T L  GT Y+  +++              +T  D P+G    + 
Sbjct: 864  RPNTIDFGKDDQHFTVTGLHKGTTYIFRLAAKNRAGLGEEFEKEIRTPEDLPSGFPQNLH 923

Query: 1457 FSDITANSFTVHWIAPRATITGYRIRHHPEHFSGRPREDRVPH--SRNSITLTNLTPGTE 1514
             + +T ++  + W  P       RI  +   F     +  + +  +    TLT L P T 
Sbjct: 924  VTGLTTSTTELAWDPPVLAERNGRIISYTVVFRDINSQQELQNITTDTRFTLTGLKPDTT 983

Query: 1515 YVVSIVALNGREESPLLIGQQSTVSDV----PRDLEVVAATPTSLLISWDAP--AVTVRY 1568
            Y + + A   +   PL    QS    V     ++  V AA  TS+L+SW+ P    +   
Sbjct: 984  YDIKVRAWTSKGSGPLSPSIQSRTMPVEQVFAKNFRVAAAMKTSVLLSWEVPDSYKSAVP 1043

Query: 1569 YRITYGETGGNSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISIN 1628
            ++I Y         Q   V G      I+ L+P  +Y+   + +  RG S    + + ++
Sbjct: 1044 FKILYNG-------QSVEVDGHSMRKLIADLQPNTEYS---FVLMNRGSSAGGLQHL-VS 1092

Query: 1629 YRTEID 1634
             RT  D
Sbjct: 1093 IRTAPD 1098



 Score =  115 bits (289), Expect = 4e-25
 Identities = 182/811 (22%), Positives = 333/811 (41%), Gaps = 109/811 (13%)

Query: 1264 IPEVPQLTDLSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIFEDFVDSSVGYY 1323
            +P+ P   DL   + T +S+ L W   NS  +  Y I   AAG   P F++    +   Y
Sbjct: 318  LPKPP--IDLVVTETTATSVTLTWDSGNSEPVTYYGIQYRAAGTEGP-FQEVDGVATTRY 374

Query: 1324 TVTGLEPGIDYDISVITLINGGESAPTTLT-----QQTAVPPPTDLRFTNIGPDTMRVTW 1378
            ++ GL P  +Y   V+ + + G   P+        +Q    PP  ++   +   TM V W
Sbjct: 375  SIGGLSPFSEYAFRVLAVNSIGRGPPSEAVRARTGEQAPSSPPRRVQARMLSASTMLVQW 434

Query: 1379 APP--PSIDLTNFLVRYSPVKNEEDVAELSISPSDNAVVLT--NLLPGTEY---VVSVSS 1431
             PP  P+  +  + V Y+P       A    + +D  ++ T  +LLPG  Y   V++ ++
Sbjct: 435  EPPEEPNGLVRGYRVYYTPDSRRPPNAWHKHN-TDAGLLTTVGSLLPGITYSLRVLAFTA 493

Query: 1432 VYEQHESTPLRGRQKTGLDSPTGIDFSDITANS-FTVHWIAP-RATITGYRIRHHPEHFS 1489
            V +   S  ++ + + G+ +      +++ +++   + W+ P +  I  Y + +      
Sbjct: 494  VGDGPPSPTIQVKTQQGVPAQPADFQAEVESDTRIQLSWLLPPQERIIMYELVYWAAEDE 553

Query: 1490 GRPREDRVPHSRNSITLTNLTPGTEYVVSIVALNGREE---SPLLIGQ--QSTVSDVPRD 1544
             +  +     + +S TL +L P T Y   + A +       +P +  +  QST S  P+ 
Sbjct: 554  DQQHKVTFDPT-SSYTLEDLKPDTLYRFQLAARSDMGVGVFTPTIEARTAQSTPSAPPQK 612

Query: 1545 LEVVAATPTSLLISWDAPAVTVR-----YYRITY----GETGGNSPVQEFTVPGSKSTAT 1595
            +  V+   T++ +SW  P    R      Y + Y    GE  G   V    +    S+  
Sbjct: 613  VMCVSMGSTTVRVSWVPPPADSRNGVITQYSVAYEAVDGEDRGRHVVDG--ISREHSSWD 670

Query: 1596 ISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPS----QMQVTDVQDNSISV 1651
            + GL+   +Y + V A T  G  P SS P+ +  RT+ D PS    +++V  +   ++ V
Sbjct: 671  LVGLEKWTEYRVWVRAHTDVGPGPESS-PVLV--RTDEDVPSGPPRKVEVEPLNSTAVHV 727

Query: 1652 KW---LPSSS--PVTGYRVTTT------PKNGP-------GPTKTKTAGPDQTEMTIEGL 1693
             W   +PS     + GY+VT        P+  P          + +    +  E TI GL
Sbjct: 728  YWKLPVPSKQHGQIRGYQVTYVRLENGEPRGLPIIQDVMLAEAQWRPEESEDYETTISGL 787

Query: 1694 QPTVEYVVSVYAQNPSGE---SQPLVQTAVTNIDRPKGLAFTDVDVDSIKIAWESPQ--- 1747
             P   Y V+V A    G+   S+P + T    +     +  +   +++  + W  P+   
Sbjct: 788  TPETTYSVTVAAYTTKGDGARSKPKIVTTTGAVPGRPTMMISTTAMNTALLQWHPPKELP 847

Query: 1748 GQVSRYRVTYSSPEDGIHELFPAPDGEEDTA-ELQGLRPGSEYTVSVVA-----LHDDME 1801
            G++  YR+ Y   ++          G++D    + GL  G+ Y   + A     L ++ E
Sbjct: 848  GELLGYRLQYCRADEARPNTIDF--GKDDQHFTVTGLHKGTTYIFRLAAKNRAGLGEEFE 905

Query: 1802 SQPLIGTQSTAIPAPTDLKFTQVTPTSLSAQWTPP-----NVQLTGYRVRVTPKEKTGPM 1856
             + +   +      P +L  T +T ++    W PP     N ++  Y V           
Sbjct: 906  KE-IRTPEDLPSGFPQNLHVTGLTTSTTELAWDPPVLAERNGRIISYTVVF---RDINSQ 961

Query: 1857 KEINLAPDSSSVVVSGLMVATKYEVSVYALKDTLTSRPAQGVVTTLENVSPP------RR 1910
            +E+      +   ++GL   T Y++ V A     TS+ +  +  ++++ + P      + 
Sbjct: 962  QELQNITTDTRFTLTGLKPDTTYDIKVRAW----TSKGSGPLSPSIQSRTMPVEQVFAKN 1017

Query: 1911 ARVTDATETTITISWRTKTETITGFQVDAVPA----NGQTPIQRTIKPDVRSYT--ITGL 1964
             RV  A +T++ +SW      +      AVP     NGQ+     ++ D  S    I  L
Sbjct: 1018 FRVAAAMKTSVLLSWE-----VPDSYKSAVPFKILYNGQS-----VEVDGHSMRKLIADL 1067

Query: 1965 QPGTDYKIYLYTLNDNARSSPVVIDASTAID 1995
            QP T+Y   L     +A     ++   TA D
Sbjct: 1068 QPNTEYSFVLMNRGSSAGGLQHLVSIRTAPD 1098



 Score =  110 bits (274), Expect = 2e-23
 Identities = 184/808 (22%), Positives = 304/808 (37%), Gaps = 90/808 (11%)

Query: 1053 LRNLQPASEYTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVTETTIVITWTPA-- 1110
            L N+  ++ YT   ++  G  E+     V    +P   I    TE T T++ +TW     
Sbjct: 287  LSNVVRSANYTCVAISSLGMIEATAQVTVKALPKP--PIDLVVTETTATSVTLTWDSGNS 344

Query: 1111 -PRIGFKLGVRPSQGGEAPREVTSDSGSI--VVSGLTPGVEYVYTIQVLRD-GQERDAPI 1166
             P   + +  R + G E P +      +    + GL+P  EY + +  +   G+   +  
Sbjct: 345  EPVTYYGIQYRAA-GTEGPFQEVDGVATTRYSIGGLSPFSEYAFRVLAVNSIGRGPPSEA 403

Query: 1167 VNKVV---TPLSPPTNLHLEANPDTGVLTVSWERSTTPD--ITGYRITTTPTNGQQGNSL 1221
            V        P SPP  +       + +L V WE    P+  + GYR+  TP + +  N+ 
Sbjct: 404  VRARTGEQAPSSPPRRVQARMLSASTML-VQWEPPEEPNGLVRGYRVYYTPDSRRPPNAW 462

Query: 1222 EEVVHADQSSCTFDNLSPGLEYNVSVYT---VKDDKESVPISDTIIPEVP-QLTDLSFVD 1277
             +         T  +L PG+ Y++ V     V D   S  I       VP Q  D     
Sbjct: 463  HKHNTDAGLLTTVGSLLPGITYSLRVLAFTAVGDGPPSPTIQVKTQQGVPAQPADFQAEV 522

Query: 1278 ITDSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIFEDFVDSSVGYYTVTGLEPGIDY--D 1335
             +D+ I L W       II Y +   AA +     +   D +  Y T+  L+P   Y   
Sbjct: 523  ESDTRIQLSWLLPPQERIIMYELVYWAAEDEDQQHKVTFDPTSSY-TLEDLKPDTLYRFQ 581

Query: 1336 ISVITLINGGESAPTT---LTQQTAVPPPTDLRFTNIGPDTMRVTWAPPPSID----LTN 1388
            ++  + +  G   PT      Q T   PP  +   ++G  T+RV+W PPP+      +T 
Sbjct: 582  LAARSDMGVGVFTPTIEARTAQSTPSAPPQKVMCVSMGSTTVRVSWVPPPADSRNGVITQ 641

Query: 1389 FLVRYSPVKNEEDVAEL--SISPSDNAVVLTNLLPGTEYVVSV---SSVYEQHESTPLRG 1443
            + V Y  V  E+    +   IS   ++  L  L   TEY V V   + V    ES+P+  
Sbjct: 642  YSVAYEAVDGEDRGRHVVDGISREHSSWDLVGLEKWTEYRVWVRAHTDVGPGPESSPVLV 701

Query: 1444 RQKTGLDS--PTGIDFSDITANSFTVHWIAP-----RATITGYRIRHHPEHFSGRPR--- 1493
            R    + S  P  ++   + + +  V+W  P        I GY++  +    +G PR   
Sbjct: 702  RTDEDVPSGPPRKVEVEPLNSTAVHVYWKLPVPSKQHGQIRGYQVT-YVRLENGEPRGLP 760

Query: 1494 ----------EDRVPHSRN-SITLTNLTPGTEYVVSIVAL----NGREESPLLIGQQSTV 1538
                      + R   S +   T++ LTP T Y V++ A     +G    P ++     V
Sbjct: 761  IIQDVMLAEAQWRPEESEDYETTISGLTPETTYSVTVAAYTTKGDGARSKPKIVTTTGAV 820

Query: 1539 SDVPRDLEVVAATPTSLLISWDAPAV---TVRYYRITYGETGGNSPVQEFTVPGSKSTA- 1594
               P  +    A  T+LL  W  P      +  YR+ Y       P    T+   K    
Sbjct: 821  PGRPTMMISTTAMNTALL-QWHPPKELPGELLGYRLQYCRADEARP---NTIDFGKDDQH 876

Query: 1595 -TISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQMQVTDVQDNSISVKW 1653
             T++GL  G  Y   + A    G      K I          P  + VT +  ++  + W
Sbjct: 877  FTVTGLHKGTTYIFRLAAKNRAGLGEEFEKEIRTPEDLPSGFPQNLHVTGLTTSTTELAW 936

Query: 1654 LP-----SSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTVEYVVSV--YAQ 1706
             P      +  +  Y V     N     +  T     T  T+ GL+P   Y + V  +  
Sbjct: 937  DPPVLAERNGRIISYTVVFRDINSQQELQNITT---DTRFTLTGLKPDTTYDIKVRAWTS 993

Query: 1707 NPSGESQPLVQTAVTNIDR--PKGLAFTDVDVDSIKIAWESPQGQVSR--YRVTYSSPED 1762
              SG   P +Q+    +++   K          S+ ++WE P    S   +++ Y+    
Sbjct: 994  KGSGPLSPSIQSRTMPVEQVFAKNFRVAAAMKTSVLLSWEVPDSYKSAVPFKILYNGQSV 1053

Query: 1763 GIHELFPAPDGEEDTAELQGLRPGSEYT 1790
             +       DG      +  L+P +EY+
Sbjct: 1054 EV-------DGHSMRKLIADLQPNTEYS 1074



 Score =  105 bits (261), Expect = 7e-22
 Identities = 168/782 (21%), Positives = 286/782 (36%), Gaps = 90/782 (11%)

Query: 990  TAQQTTKL--DAPTNLQFVNETDSTVLVRWTPPRAQ-ITGYRLTVGLTRRGQPRQYNVGP 1046
            TAQ T K     P +L     T ++V + W    ++ +T Y +         P Q   G 
Sbjct: 310  TAQVTVKALPKPPIDLVVTETTATSVTLTWDSGNSEPVTYYGIQYRAAGTEGPFQEVDGV 369

Query: 1047 SVSKYPLRNLQPASEYTVSLVAIKGNQESPKATGV-FTTLQPGSSIPPYNTE---VTETT 1102
            + ++Y +  L P SEY   ++A+      P +  V   T +   S PP   +   ++ +T
Sbjct: 370  ATTRYSIGGLSPFSEYAFRVLAVNSIGRGPPSEAVRARTGEQAPSSPPRRVQARMLSAST 429

Query: 1103 IVITWTPAPR-----IGFKLGVRPS--QGGEAPREVTSDSGSI-VVSGLTPGVEY---VY 1151
            +++ W P         G+++   P   +   A  +  +D+G +  V  L PG+ Y   V 
Sbjct: 430  MLVQWEPPEEPNGLVRGYRVYYTPDSRRPPNAWHKHNTDAGLLTTVGSLLPGITYSLRVL 489

Query: 1152 TIQVLRDGQERDAPIVNKVVTPLSPPTNLHLEANPDTGVLTVSWERSTTPDITGYRITTT 1211
                + DG       V       + P +   E   DT +  +SW       I  Y +   
Sbjct: 490  AFTAVGDGPPSPTIQVKTQQGVPAQPADFQAEVESDTRI-QLSWLLPPQERIIMYELVYW 548

Query: 1212 PTNGQQGNSLEEVVHADQSSCTFDNLSPGLEYNVSVYTVKDDKESVPISDTIIPEVPQLT 1271
                +  +   +V     SS T ++L P   Y   +   + D      + TI     Q T
Sbjct: 549  AAEDE--DQQHKVTFDPTSSYTLEDLKPDTLYRFQL-AARSDMGVGVFTPTIEARTAQST 605

Query: 1272 ------DLSFVDITDSSIGLRWTPLNSSTIIGYRITVVAAGEGIPIFE------DFVDSS 1319
                   +  V +  +++ + W P  + +  G       A E +   +      D +   
Sbjct: 606  PSAPPQKVMCVSMGSTTVRVSWVPPPADSRNGVITQYSVAYEAVDGEDRGRHVVDGISRE 665

Query: 1320 VGYYTVTGLEPGIDYDISVITLIN---GGESAPTTLTQQTAVP--PPTDLRFTNIGPDTM 1374
               + + GLE   +Y + V    +   G ES+P  +     VP  PP  +    +    +
Sbjct: 666  HSSWDLVGLEKWTEYRVWVRAHTDVGPGPESSPVLVRTDEDVPSGPPRKVEVEPLNSTAV 725

Query: 1375 RVTW-APPPS-------------IDLTNFLVRYSPVKNEEDVAELSISP---SDNAVVLT 1417
             V W  P PS             + L N   R  P+  +  +AE    P    D    ++
Sbjct: 726  HVYWKLPVPSKQHGQIRGYQVTYVRLENGEPRGLPIIQDVMLAEAQWRPEESEDYETTIS 785

Query: 1418 NLLPGTEYVVSVSSVYEQHESTPLRGRQKTGLDSPTG-------IDFSDITANSFTVHWI 1470
             L P T Y V+V++   + +      R K  + + TG       +  S    N+  + W 
Sbjct: 786  GLTPETTYSVTVAAYTTKGDG----ARSKPKIVTTTGAVPGRPTMMISTTAMNTALLQWH 841

Query: 1471 APR---ATITGYRIRHHPEHFSGRPREDRVPHSRNSITLTNLTPGTEYVVSIVALN---- 1523
             P+     + GYR+++       RP            T+T L  GT Y+  + A N    
Sbjct: 842  PPKELPGELLGYRLQYCRAD-EARPNTIDFGKDDQHFTVTGLHKGTTYIFRLAAKNRAGL 900

Query: 1524 GREESPLLIGQQSTVSDVPRDLEVVAATPTSLLISWDAPAVTVR-----YYRITYGETGG 1578
            G E    +   +   S  P++L V   T ++  ++WD P +  R      Y + + +   
Sbjct: 901  GEEFEKEIRTPEDLPSGFPQNLHVTGLTTSTTELAWDPPVLAERNGRIISYTVVFRDINS 960

Query: 1579 NSPVQEFTVPGSKSTATISGLKPGVDYTITVYAVTGRGDSPASSKPISINYRTEIDKPSQ 1638
               +Q  T   + +  T++GLKP   Y I V A T +G  P S    S     E      
Sbjct: 961  QQELQNIT---TDTRFTLTGLKPDTTYDIKVRAWTSKGSGPLSPSIQSRTMPVEQVFAKN 1017

Query: 1639 MQVTDVQDNSISVKW-LPSSSPVTGYRVTTTPKNGPGPTKTKTAGPDQTEMTIEGLQPTV 1697
             +V      S+ + W +P S     Y+     K        +  G    ++ I  LQP  
Sbjct: 1018 FRVAAAMKTSVLLSWEVPDS-----YKSAVPFKILYNGQSVEVDGHSMRKL-IADLQPNT 1071

Query: 1698 EY 1699
            EY
Sbjct: 1072 EY 1073



 Score = 82.8 bits (203), Expect = 4e-15
 Identities = 126/575 (21%), Positives = 224/575 (38%), Gaps = 76/575 (13%)

Query: 628  IQWNAPQPSHISKY-ILRWRPKNSVGRWKEATIPGHLNSYTIKGLKPGVVYEGQLISIQQ 686
            + W  P    I  Y ++ W  ++   + K    P   +SYT++ LKP  +Y  QL +   
Sbjct: 530  LSWLLPPQERIIMYELVYWAAEDEDQQHKVTFDP--TSSYTLEDLKPDTLYRFQLAARSD 587

Query: 687  YGHQEVTRFDFTTTSTSTPVTSNTVTGETTPFSPLVATSESVTEITASSFVVSWV----- 741
             G    T      T+ STP         + P   ++  S   T +      VSWV     
Sbjct: 588  MGVGVFTPTIEARTAQSTP---------SAPPQKVMCVSMGSTTVR-----VSWVPPPAD 633

Query: 742  SASDTVSGFRVEYELSEEGDEPQYL--DLPSTATSVNIPDLLPGRKYIVNVYQISEDG-- 797
            S +  ++ + V YE  +  D  +++   +    +S ++  L    +Y V V   ++ G  
Sbjct: 634  SRNGVITQYSVAYEAVDGEDRGRHVVDGISREHSSWDLVGLEKWTEYRVWVRAHTDVGPG 693

Query: 798  -EQSLILSTSQTTAPDAPPDPT-VDQVDDTSIVVRW-----SRPQAPITGYRIVYSPSVE 850
             E S +L  +    P  PP    V+ ++ T++ V W     S+    I GY++ Y     
Sbjct: 694  PESSPVLVRTDEDVPSGPPRKVEVEPLNSTAVHVYWKLPVPSKQHGQIRGYQVTYVRLEN 753

Query: 851  GSSTELNL------------PETAN--SVTLSDLQPGVQYNITIYAVE---ENQESTPVV 893
            G    L +            PE +     T+S L P   Y++T+ A     +   S P +
Sbjct: 754  GEPRGLPIIQDVMLAEAQWRPEESEDYETTISGLTPETTYSVTVAAYTTKGDGARSKPKI 813

Query: 894  IQQETTGTPRSDTVPSPRDLQFVEVTDVKVTIM-WTPPE---SAVTGYRVDVIPVNLPGE 949
            +   TTG      VP  R    +  T +   ++ W PP+     + GYR+     +    
Sbjct: 814  V--TTTG-----AVPG-RPTMMISTTAMNTALLQWHPPKELPGELLGYRLQYCRADEARP 865

Query: 950  HGQRLPISRNTFAEVTGLSPGVTYYFKVFAVSHGRESKPLTAQQTTKLDAPT----NLQF 1005
            +          F  VTGL  G TY F++ A +     +    +  T  D P+    NL  
Sbjct: 866  NTIDFGKDDQHFT-VTGLHKGTTYIFRLAAKNRAGLGEEFEKEIRTPEDLPSGFPQNLHV 924

Query: 1006 VNETDSTVLVRWTPP-RAQITGYRLTVGLTRR---GQPRQYNVGPSVSKYPLRNLQPASE 1061
               T ST  + W PP  A+  G  ++  +  R    Q    N+  + +++ L  L+P + 
Sbjct: 925  TGLTTSTTELAWDPPVLAERNGRIISYTVVFRDINSQQELQNI-TTDTRFTLTGLKPDTT 983

Query: 1062 YTVSLVAIKGNQESPKATGVFTTLQPGSSIPPYNTEVT---ETTIVITWTPAPRIGFKLG 1118
            Y + + A       P +  + +   P   +   N  V    +T+++++W         + 
Sbjct: 984  YDIKVRAWTSKGSGPLSPSIQSRTMPVEQVFAKNFRVAAAMKTSVLLSWEVPDSYKSAVP 1043

Query: 1119 VRPSQGGEAPREVTSDSGSIVVSGLTPGVEYVYTI 1153
             +    G++  EV   S   +++ L P  EY + +
Sbjct: 1044 FKILYNGQSV-EVDGHSMRKLIADLQPNTEYSFVL 1077


>gi|189217853 matrix metalloproteinase 2 isoform b [Homo sapiens]
          Length = 610

 Score =  146 bits (368), Expect = 3e-34
 Identities = 70/178 (39%), Positives = 97/178 (54%), Gaps = 16/178 (8%)

Query: 344 ETAVTQTYGGNSNGEPCVLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTD 403
           E  V +   GN++GE C  PF +NG+ + SCT  GR DG LWCSTT N+E+D KY FC  
Sbjct: 167 EGQVVRVKYGNADGEYCKFPFLFNGKEYNSCTDTGRSDGFLWCSTTYNFEKDGKYGFCPH 226

Query: 404 HTVLVQTRGGNSNGALCHFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPM 463
             +   T GGN+ G  C FPF +   +Y  CT+EGR D  +WCGTT++YD D+K+GFCP 
Sbjct: 227 EALF--TMGGNAEGQPCKFPFRFQGTSYDSCTTEGRTDGYRWCGTTEDYDRDKKYGFCPE 284

Query: 464 AAHEEICTTNEGV-----MYRIGDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRD 516
            A   +   +EG         +G++++          CT  G   G+  C   +   D
Sbjct: 285 TAMSTVGGNSEGAPCVFPFTFLGNKYES---------CTSAGRSDGKMWCATTANYDD 333



 Score =  145 bits (365), Expect = 6e-34
 Identities = 77/171 (45%), Positives = 97/171 (56%), Gaps = 18/171 (10%)

Query: 305 YGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPCVLPF 364
           Y  C TD+G   S G  W  T  N +      G    C   A+  T GGN+ G+PC  PF
Sbjct: 194 YNSC-TDTG--RSDGFLWCSTTYNFEKD----GKYGFCPHEALF-TMGGNAEGQPCKFPF 245

Query: 365 TYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALCHFPF 424
            + G ++ SCTTEGR DG+ WC TT +Y++D+KY FC +    + T GGNS GA C FPF
Sbjct: 246 RFQGTSYDSCTTEGRTDGYRWCGTTEDYDRDKKYGFCPE--TAMSTVGGNSEGAPCVFPF 303

Query: 425 LYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCP--------MAAHE 467
            +  + Y  CTS GR D   WC TT NYD D+K+GFCP        +AAHE
Sbjct: 304 TFLGNKYESCTSAGRSDGKMWCATTANYDDDRKWGFCPDQGYSLFLVAAHE 354


>gi|11342666 matrix metalloproteinase 2 isoform a preproprotein
           [Homo sapiens]
          Length = 660

 Score =  146 bits (368), Expect = 3e-34
 Identities = 70/178 (39%), Positives = 97/178 (54%), Gaps = 16/178 (8%)

Query: 344 ETAVTQTYGGNSNGEPCVLPFTYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTD 403
           E  V +   GN++GE C  PF +NG+ + SCT  GR DG LWCSTT N+E+D KY FC  
Sbjct: 217 EGQVVRVKYGNADGEYCKFPFLFNGKEYNSCTDTGRSDGFLWCSTTYNFEKDGKYGFCPH 276

Query: 404 HTVLVQTRGGNSNGALCHFPFLYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCPM 463
             +   T GGN+ G  C FPF +   +Y  CT+EGR D  +WCGTT++YD D+K+GFCP 
Sbjct: 277 EALF--TMGGNAEGQPCKFPFRFQGTSYDSCTTEGRTDGYRWCGTTEDYDRDKKYGFCPE 334

Query: 464 AAHEEICTTNEGV-----MYRIGDQWDKQHDMGHMMRCTCVGNGRGEWTCIAYSQLRD 516
            A   +   +EG         +G++++          CT  G   G+  C   +   D
Sbjct: 335 TAMSTVGGNSEGAPCVFPFTFLGNKYES---------CTSAGRSDGKMWCATTANYDD 383



 Score =  145 bits (365), Expect = 6e-34
 Identities = 77/171 (45%), Positives = 97/171 (56%), Gaps = 18/171 (10%)

Query: 305 YGHCVTDSGVVYSVGMQWLKTQGNKQMLCTCLGNGVSCQETAVTQTYGGNSNGEPCVLPF 364
           Y  C TD+G   S G  W  T  N +      G    C   A+  T GGN+ G+PC  PF
Sbjct: 244 YNSC-TDTG--RSDGFLWCSTTYNFEKD----GKYGFCPHEALF-TMGGNAEGQPCKFPF 295

Query: 365 TYNGRTFYSCTTEGRQDGHLWCSTTSNYEQDQKYSFCTDHTVLVQTRGGNSNGALCHFPF 424
            + G ++ SCTTEGR DG+ WC TT +Y++D+KY FC +    + T GGNS GA C FPF
Sbjct: 296 RFQGTSYDSCTTEGRTDGYRWCGTTEDYDRDKKYGFCPE--TAMSTVGGNSEGAPCVFPF 353

Query: 425 LYNNHNYTDCTSEGRRDNMKWCGTTQNYDADQKFGFCP--------MAAHE 467
            +  + Y  CTS GR D   WC TT NYD D+K+GFCP        +AAHE
Sbjct: 354 TFLGNKYESCTSAGRSDGKMWCATTANYDDDRKWGFCPDQGYSLFLVAAHE 404


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.132    0.407 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 109,721,474
Number of Sequences: 37866
Number of extensions: 5809881
Number of successful extensions: 24424
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 105
Number of HSP's successfully gapped in prelim test: 233
Number of HSP's that attempted gapping in prelim test: 11753
Number of HSP's gapped (non-prelim): 3806
length of query: 2421
length of database: 18,247,518
effective HSP length: 119
effective length of query: 2302
effective length of database: 13,741,464
effective search space: 31632850128
effective search space used: 31632850128
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 70 (31.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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