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Search of human proteins with 46370057
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|46370057 ring finger protein 216 isoform b [Homo sapiens]
(866 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|46370057 ring finger protein 216 isoform b [Homo sapiens] 1814 0.0
gi|46358403 ring finger protein 216 isoform a [Homo sapiens] 1746 0.0
gi|38045938 ring finger protein 144 [Homo sapiens] 83 1e-15
gi|5454168 RanBP-type and C3HC4-type zinc finger containing 1 is... 70 8e-12
gi|144953898 RanBP-type and C3HC4-type zinc finger containing 1 ... 70 8e-12
gi|35493801 ring finger protein 19 [Homo sapiens] 69 1e-11
gi|35493782 ring finger protein 19 [Homo sapiens] 69 1e-11
gi|34577102 ring finger protein 14 isoform 1 [Homo sapiens] 64 6e-10
gi|34577100 ring finger protein 14 isoform 1 [Homo sapiens] 64 6e-10
gi|34577098 ring finger protein 14 isoform 1 [Homo sapiens] 64 6e-10
gi|34577096 ring finger protein 14 isoform 2 [Homo sapiens] 64 6e-10
gi|4757762 ring finger protein 14 isoform 1 [Homo sapiens] 64 6e-10
gi|188219577 ring finger protein 19B isoform a [Homo sapiens] 64 8e-10
gi|188219579 ring finger protein 19B isoform b [Homo sapiens] 62 2e-09
gi|187761373 ariadne ubiquitin-conjugating enzyme E2 binding pro... 62 2e-09
gi|5453557 ariadne homolog 2 [Homo sapiens] 62 3e-09
gi|22749145 ring finger protein 217 [Homo sapiens] 58 3e-08
gi|50284696 IBR domain containing 2 [Homo sapiens] 55 4e-07
gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sa... 50 9e-06
gi|157168329 formin 1 [Homo sapiens] 45 4e-04
gi|169790973 parkin isoform 3 [Homo sapiens] 44 5e-04
gi|169790971 parkin isoform 2 [Homo sapiens] 44 5e-04
gi|169790969 parkin isoform 1 [Homo sapiens] 44 5e-04
gi|215820635 protein phosphatase 1, regulatory subunit 13 like [... 44 6e-04
gi|63003907 protein phosphatase 1, regulatory subunit 13 like [H... 44 6e-04
gi|224451135 splicing factor, arginine/serine-rich 15 isoform 3 ... 42 0.002
gi|224451133 splicing factor, arginine/serine-rich 15 isoform 2 ... 42 0.002
gi|40789229 splicing factor, arginine/serine-rich 15 isoform 1 [... 42 0.002
gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens] 41 0.004
gi|239753435 PREDICTED: hypothetical protein XP_002345651 [Homo ... 41 0.005
>gi|46370057 ring finger protein 216 isoform b [Homo sapiens]
Length = 866
Score = 1814 bits (4698), Expect = 0.0
Identities = 866/866 (100%), Positives = 866/866 (100%)
Query: 1 MEEGNNNEEVIHLNNFHCHRGQEWINLRDGPITISDSSDEERIPMLVTPAPQQHEEEDLD 60
MEEGNNNEEVIHLNNFHCHRGQEWINLRDGPITISDSSDEERIPMLVTPAPQQHEEEDLD
Sbjct: 1 MEEGNNNEEVIHLNNFHCHRGQEWINLRDGPITISDSSDEERIPMLVTPAPQQHEEEDLD 60
Query: 61 DDVILTEDDSEDDYGEFLDLGPPGISEFTKPSGQTEREPKPGPSHNQAANDIVNPRSEQK 120
DDVILTEDDSEDDYGEFLDLGPPGISEFTKPSGQTEREPKPGPSHNQAANDIVNPRSEQK
Sbjct: 61 DDVILTEDDSEDDYGEFLDLGPPGISEFTKPSGQTEREPKPGPSHNQAANDIVNPRSEQK 120
Query: 121 VIILEEGSLLYTESDPLETQNQSSEDSETELLSNLGESAALADDQAIEEDCWLDHPYFQS 180
VIILEEGSLLYTESDPLETQNQSSEDSETELLSNLGESAALADDQAIEEDCWLDHPYFQS
Sbjct: 121 VIILEEGSLLYTESDPLETQNQSSEDSETELLSNLGESAALADDQAIEEDCWLDHPYFQS 180
Query: 181 LNQQPREITNQVVPQERQPEAELGRLLFQHEFPGPAFPRPEPQQGGISGPSSPQPAHPLG 240
LNQQPREITNQVVPQERQPEAELGRLLFQHEFPGPAFPRPEPQQGGISGPSSPQPAHPLG
Sbjct: 181 LNQQPREITNQVVPQERQPEAELGRLLFQHEFPGPAFPRPEPQQGGISGPSSPQPAHPLG 240
Query: 241 EFEDQQLASDDEEPGPAFPMQESQEPNLENIWGQEAAEVDQELVELLVKETEARFPDVAN 300
EFEDQQLASDDEEPGPAFPMQESQEPNLENIWGQEAAEVDQELVELLVKETEARFPDVAN
Sbjct: 241 EFEDQQLASDDEEPGPAFPMQESQEPNLENIWGQEAAEVDQELVELLVKETEARFPDVAN 300
Query: 301 GFIEEIIHFKNYYDLNVLCNFLLENPDYPKREDRIIINPSSSLLASQDETKLPKIDFFDY 360
GFIEEIIHFKNYYDLNVLCNFLLENPDYPKREDRIIINPSSSLLASQDETKLPKIDFFDY
Sbjct: 301 GFIEEIIHFKNYYDLNVLCNFLLENPDYPKREDRIIINPSSSLLASQDETKLPKIDFFDY 360
Query: 361 SKLTPLDQRCFIQAADLLMADFKVLSSQDIKWALHELKGHYAITRKALSDAIKKWQELSP 420
SKLTPLDQRCFIQAADLLMADFKVLSSQDIKWALHELKGHYAITRKALSDAIKKWQELSP
Sbjct: 361 SKLTPLDQRCFIQAADLLMADFKVLSSQDIKWALHELKGHYAITRKALSDAIKKWQELSP 420
Query: 421 ETSGKRKKRKQMNQYSYIDFKFEQGDIKIEKRMFFLENKRRHCRSYDRRALLPAVQQEQE 480
ETSGKRKKRKQMNQYSYIDFKFEQGDIKIEKRMFFLENKRRHCRSYDRRALLPAVQQEQE
Sbjct: 421 ETSGKRKKRKQMNQYSYIDFKFEQGDIKIEKRMFFLENKRRHCRSYDRRALLPAVQQEQE 480
Query: 481 FYEQKIKEMAEHEDFLLALQMNEEQYQKDGQLIECRCCYGEFPFEELTQCADAHLFCKEC 540
FYEQKIKEMAEHEDFLLALQMNEEQYQKDGQLIECRCCYGEFPFEELTQCADAHLFCKEC
Sbjct: 481 FYEQKIKEMAEHEDFLLALQMNEEQYQKDGQLIECRCCYGEFPFEELTQCADAHLFCKEC 540
Query: 541 LIRYAQEAVFGSGKLELSCMEGSCTCSFPTSELEKVLPQTILYKYYERKAEEEVAAAYAD 600
LIRYAQEAVFGSGKLELSCMEGSCTCSFPTSELEKVLPQTILYKYYERKAEEEVAAAYAD
Sbjct: 541 LIRYAQEAVFGSGKLELSCMEGSCTCSFPTSELEKVLPQTILYKYYERKAEEEVAAAYAD 600
Query: 601 ELVRCPSCSFPALLDSDVKRFSCPNPHCRKETCRKCQGLWKEHNGLTCEELAEKDDIKYR 660
ELVRCPSCSFPALLDSDVKRFSCPNPHCRKETCRKCQGLWKEHNGLTCEELAEKDDIKYR
Sbjct: 601 ELVRCPSCSFPALLDSDVKRFSCPNPHCRKETCRKCQGLWKEHNGLTCEELAEKDDIKYR 660
Query: 661 TSIEEKMTAARIRKCHKCGTGLIKSEGCNRMSCRCGAQMCYLCRVSINGYDHFCQHPRSP 720
TSIEEKMTAARIRKCHKCGTGLIKSEGCNRMSCRCGAQMCYLCRVSINGYDHFCQHPRSP
Sbjct: 661 TSIEEKMTAARIRKCHKCGTGLIKSEGCNRMSCRCGAQMCYLCRVSINGYDHFCQHPRSP 720
Query: 721 GAPCQECSRCSLWTDPTEDDEKLIEEIQKEAEEEQKRKNGENTFKRIGPPLEKPVEKVQR 780
GAPCQECSRCSLWTDPTEDDEKLIEEIQKEAEEEQKRKNGENTFKRIGPPLEKPVEKVQR
Sbjct: 721 GAPCQECSRCSLWTDPTEDDEKLIEEIQKEAEEEQKRKNGENTFKRIGPPLEKPVEKVQR 780
Query: 781 VEALPRPVPQNLPQPQMPPYAFAHPPFPLPPVRPVFNNFPLNMGPIPAPYVPPLPNVRVN 840
VEALPRPVPQNLPQPQMPPYAFAHPPFPLPPVRPVFNNFPLNMGPIPAPYVPPLPNVRVN
Sbjct: 781 VEALPRPVPQNLPQPQMPPYAFAHPPFPLPPVRPVFNNFPLNMGPIPAPYVPPLPNVRVN 840
Query: 841 YDFGPIHMPLEHNLPMHFGPQPRHRF 866
YDFGPIHMPLEHNLPMHFGPQPRHRF
Sbjct: 841 YDFGPIHMPLEHNLPMHFGPQPRHRF 866
>gi|46358403 ring finger protein 216 isoform a [Homo sapiens]
Length = 923
Score = 1746 bits (4523), Expect = 0.0
Identities = 849/923 (91%), Positives = 855/923 (92%), Gaps = 57/923 (6%)
Query: 1 MEEGNNNEEVIHLNNFHCHRGQEWINLRDGPITISDSSDEERIPM--------------- 45
MEEGNNNEEVIHLNNFHCHRGQEWINLRDGPITISDSSDEERIPM
Sbjct: 1 MEEGNNNEEVIHLNNFHCHRGQEWINLRDGPITISDSSDEERIPMLVTPAPQQHEEEDLD 60
Query: 46 -----------------LVTPAPQQHEEEDLDDDVIL----------------------- 65
L+ PA Q + + L ++
Sbjct: 61 DDVILTETNKPQRSRPNLIKPAAQWQDLKRLGEERPKKSRAAFESDKSSYFSVCNNPLFD 120
Query: 66 --TEDDSEDDYGEFLDLGPPGISEFTKPSGQTEREPKPGPSHNQAANDIVNPRSEQKVII 123
+DDSEDDYGEFLDLGPPGISEFTKPSGQTEREPKPGPSHNQAANDIVNPRSEQKVII
Sbjct: 121 SGAQDDSEDDYGEFLDLGPPGISEFTKPSGQTEREPKPGPSHNQAANDIVNPRSEQKVII 180
Query: 124 LEEGSLLYTESDPLETQNQSSEDSETELLSNLGESAALADDQAIEEDCWLDHPYFQSLNQ 183
LEEGSLLYTESDPLETQNQSSEDSETELLSNLGESAALADDQAIEEDCWLDHPYFQSLNQ
Sbjct: 181 LEEGSLLYTESDPLETQNQSSEDSETELLSNLGESAALADDQAIEEDCWLDHPYFQSLNQ 240
Query: 184 QPREITNQVVPQERQPEAELGRLLFQHEFPGPAFPRPEPQQGGISGPSSPQPAHPLGEFE 243
QPREITNQVVPQERQPEAELGRLLFQHEFPGPAFPRPEPQQGGISGPSSPQPAHPLGEFE
Sbjct: 241 QPREITNQVVPQERQPEAELGRLLFQHEFPGPAFPRPEPQQGGISGPSSPQPAHPLGEFE 300
Query: 244 DQQLASDDEEPGPAFPMQESQEPNLENIWGQEAAEVDQELVELLVKETEARFPDVANGFI 303
DQQLASDDEEPGPAFPMQESQEPNLENIWGQEAAEVDQELVELLVKETEARFPDVANGFI
Sbjct: 301 DQQLASDDEEPGPAFPMQESQEPNLENIWGQEAAEVDQELVELLVKETEARFPDVANGFI 360
Query: 304 EEIIHFKNYYDLNVLCNFLLENPDYPKREDRIIINPSSSLLASQDETKLPKIDFFDYSKL 363
EEIIHFKNYYDLNVLCNFLLENPDYPKREDRIIINPSSSLLASQDETKLPKIDFFDYSKL
Sbjct: 361 EEIIHFKNYYDLNVLCNFLLENPDYPKREDRIIINPSSSLLASQDETKLPKIDFFDYSKL 420
Query: 364 TPLDQRCFIQAADLLMADFKVLSSQDIKWALHELKGHYAITRKALSDAIKKWQELSPETS 423
TPLDQRCFIQAADLLMADFKVLSSQDIKWALHELKGHYAITRKALSDAIKKWQELSPETS
Sbjct: 421 TPLDQRCFIQAADLLMADFKVLSSQDIKWALHELKGHYAITRKALSDAIKKWQELSPETS 480
Query: 424 GKRKKRKQMNQYSYIDFKFEQGDIKIEKRMFFLENKRRHCRSYDRRALLPAVQQEQEFYE 483
GKRKKRKQMNQYSYIDFKFEQGDIKIEKRMFFLENKRRHCRSYDRRALLPAVQQEQEFYE
Sbjct: 481 GKRKKRKQMNQYSYIDFKFEQGDIKIEKRMFFLENKRRHCRSYDRRALLPAVQQEQEFYE 540
Query: 484 QKIKEMAEHEDFLLALQMNEEQYQKDGQLIECRCCYGEFPFEELTQCADAHLFCKECLIR 543
QKIKEMAEHEDFLLALQMNEEQYQKDGQLIECRCCYGEFPFEELTQCADAHLFCKECLIR
Sbjct: 541 QKIKEMAEHEDFLLALQMNEEQYQKDGQLIECRCCYGEFPFEELTQCADAHLFCKECLIR 600
Query: 544 YAQEAVFGSGKLELSCMEGSCTCSFPTSELEKVLPQTILYKYYERKAEEEVAAAYADELV 603
YAQEAVFGSGKLELSCMEGSCTCSFPTSELEKVLPQTILYKYYERKAEEEVAAAYADELV
Sbjct: 601 YAQEAVFGSGKLELSCMEGSCTCSFPTSELEKVLPQTILYKYYERKAEEEVAAAYADELV 660
Query: 604 RCPSCSFPALLDSDVKRFSCPNPHCRKETCRKCQGLWKEHNGLTCEELAEKDDIKYRTSI 663
RCPSCSFPALLDSDVKRFSCPNPHCRKETCRKCQGLWKEHNGLTCEELAEKDDIKYRTSI
Sbjct: 661 RCPSCSFPALLDSDVKRFSCPNPHCRKETCRKCQGLWKEHNGLTCEELAEKDDIKYRTSI 720
Query: 664 EEKMTAARIRKCHKCGTGLIKSEGCNRMSCRCGAQMCYLCRVSINGYDHFCQHPRSPGAP 723
EEKMTAARIRKCHKCGTGLIKSEGCNRMSCRCGAQMCYLCRVSINGYDHFCQHPRSPGAP
Sbjct: 721 EEKMTAARIRKCHKCGTGLIKSEGCNRMSCRCGAQMCYLCRVSINGYDHFCQHPRSPGAP 780
Query: 724 CQECSRCSLWTDPTEDDEKLIEEIQKEAEEEQKRKNGENTFKRIGPPLEKPVEKVQRVEA 783
CQECSRCSLWTDPTEDDEKLIEEIQKEAEEEQKRKNGENTFKRIGPPLEKPVEKVQRVEA
Sbjct: 781 CQECSRCSLWTDPTEDDEKLIEEIQKEAEEEQKRKNGENTFKRIGPPLEKPVEKVQRVEA 840
Query: 784 LPRPVPQNLPQPQMPPYAFAHPPFPLPPVRPVFNNFPLNMGPIPAPYVPPLPNVRVNYDF 843
LPRPVPQNLPQPQMPPYAFAHPPFPLPPVRPVFNNFPLNMGPIPAPYVPPLPNVRVNYDF
Sbjct: 841 LPRPVPQNLPQPQMPPYAFAHPPFPLPPVRPVFNNFPLNMGPIPAPYVPPLPNVRVNYDF 900
Query: 844 GPIHMPLEHNLPMHFGPQPRHRF 866
GPIHMPLEHNLPMHFGPQPRHRF
Sbjct: 901 GPIHMPLEHNLPMHFGPQPRHRF 923
>gi|38045938 ring finger protein 144 [Homo sapiens]
Length = 292
Score = 83.2 bits (204), Expect = 1e-15
Identities = 57/207 (27%), Positives = 93/207 (44%), Gaps = 14/207 (6%)
Query: 512 LIECRCCYGEFPFEELTQCADAH-LFCKECLIRYAQEAVFGSGKLELSCMEGSCTCS--F 568
L+ C+ C GE+P E++T A +FC CL +Y + + + +SC + +C
Sbjct: 17 LVSCKLCLGEYPVEQMTTIAQCQCIFCTLCLKQYVELLIKEGLETAISCPDAACPKQGHL 76
Query: 569 PTSELEKVLPQTILYKYYERKAEEEVAAAYADELVRCPSCSFPALLDSDVKRFSCPNP-- 626
+E+E ++ I+ +Y + + E EV + CP+ + A+ P P
Sbjct: 77 QENEIECMVAAEIMQRYKKLQFEREV--LFDPCRTWCPASTCQAVCQLQDVGLQTPQPVQ 134
Query: 627 --HCRKETCRKCQGLWKEHNGLTCEELAEKDDIKYRTSIEEKMTA--ARIRKCHKCGTGL 682
CR E C C+ W H G C E + TS KM A I++C KC +
Sbjct: 135 CKACRMEFCSTCKASW--HPGQGCPETMPITFLPGETSAAFKMEEDDAPIKRCPKCKVYI 192
Query: 683 IKSEGCNRMSCR-CGAQMCYLCRVSIN 708
+ EGC +M C+ C C+ C S++
Sbjct: 193 ERDEGCAQMMCKNCKHAFCWYCLESLD 219
>gi|5454168 RanBP-type and C3HC4-type zinc finger containing 1
isoform 1 [Homo sapiens]
Length = 468
Score = 70.1 bits (170), Expect = 8e-12
Identities = 68/296 (22%), Positives = 119/296 (40%), Gaps = 56/296 (18%)
Query: 467 DRRALLPAVQQEQEFYEQKIKEMAEHEDFLLALQMNEEQYQKDGQLIECRCCYGEF-PFE 525
+ RA L ++ Y+Q+ K+ + ++L +Q+++ + + EC CY P E
Sbjct: 193 EERARLAGEEEALRQYQQR-KQQQQEGNYLQHVQLDQRSLVLNTEPAECPVCYSVLAPGE 251
Query: 526 ELTQCADAHLFCKECLIRYAQEAVFGSGKLELSCMEGSCTCSFPTSELEKVLPQTILYKY 585
+ H FC+ECL Q + S + E+SC T S LE+ + + +
Sbjct: 252 AVVLRECLHTFCRECL----QGTIRNSQEAEVSCPFIDNTYSCSGKLLEREIKALLTPED 307
Query: 586 YERK-------AEEEVAAAYADELVRCPSCSFPALLDSDVKRFSCPNPHCRKETCRKCQG 638
Y+R AE A +Y + P C + DV F+C P C C C+
Sbjct: 308 YQRFLDLGISIAENRSAFSYH---CKTPDCKGWCFFEDDVNEFTC--PVCFHVNCLLCKA 362
Query: 639 LWKEHNGLTCEELAEKDDIKYRTSIEEKMTAARIR---------KCHKCGTGLIKSEGCN 689
+ H + C+E E ++ + + + T ++ +C +C + K +GC+
Sbjct: 363 I---HEQMNCKEYQEDLALRAQNDVAARQTTEMLKVMLQQGEAMRCPQCQIVVQKKDGCD 419
Query: 690 RMSCR-CGAQMCYL-----------------CRVSINGYDHFCQHPRSPGAPCQEC 727
+ C C ++C++ CR +NG C HP CQ C
Sbjct: 420 WIRCTVCHTEICWVTKGPRWGPGGPGDTSGGCRCRVNGIP--C-HP-----SCQNC 467
>gi|144953898 RanBP-type and C3HC4-type zinc finger containing 1
isoform 2 [Homo sapiens]
Length = 510
Score = 70.1 bits (170), Expect = 8e-12
Identities = 68/296 (22%), Positives = 119/296 (40%), Gaps = 56/296 (18%)
Query: 467 DRRALLPAVQQEQEFYEQKIKEMAEHEDFLLALQMNEEQYQKDGQLIECRCCYGEF-PFE 525
+ RA L ++ Y+Q+ K+ + ++L +Q+++ + + EC CY P E
Sbjct: 235 EERARLAGEEEALRQYQQR-KQQQQEGNYLQHVQLDQRSLVLNTEPAECPVCYSVLAPGE 293
Query: 526 ELTQCADAHLFCKECLIRYAQEAVFGSGKLELSCMEGSCTCSFPTSELEKVLPQTILYKY 585
+ H FC+ECL Q + S + E+SC T S LE+ + + +
Sbjct: 294 AVVLRECLHTFCRECL----QGTIRNSQEAEVSCPFIDNTYSCSGKLLEREIKALLTPED 349
Query: 586 YERK-------AEEEVAAAYADELVRCPSCSFPALLDSDVKRFSCPNPHCRKETCRKCQG 638
Y+R AE A +Y + P C + DV F+C P C C C+
Sbjct: 350 YQRFLDLGISIAENRSAFSYH---CKTPDCKGWCFFEDDVNEFTC--PVCFHVNCLLCKA 404
Query: 639 LWKEHNGLTCEELAEKDDIKYRTSIEEKMTAARIR---------KCHKCGTGLIKSEGCN 689
+ H + C+E E ++ + + + T ++ +C +C + K +GC+
Sbjct: 405 I---HEQMNCKEYQEDLALRAQNDVAARQTTEMLKVMLQQGEAMRCPQCQIVVQKKDGCD 461
Query: 690 RMSCR-CGAQMCYL-----------------CRVSINGYDHFCQHPRSPGAPCQEC 727
+ C C ++C++ CR +NG C HP CQ C
Sbjct: 462 WIRCTVCHTEICWVTKGPRWGPGGPGDTSGGCRCRVNGIP--C-HP-----SCQNC 509
>gi|35493801 ring finger protein 19 [Homo sapiens]
Length = 838
Score = 69.3 bits (168), Expect = 1e-11
Identities = 62/243 (25%), Positives = 98/243 (40%), Gaps = 38/243 (15%)
Query: 510 GQLIECRCC---YGEFPFEELTQCADAHLFCKECLIRYAQEAVFGSGKLELSCMEGSCTC 566
G IEC C + + F ++ C H C +CL +Y + + S ++ +SC E CT
Sbjct: 127 GDFIECPLCLLRHSKDRFPDIMTCH--HRSCVDCLRQYLRIEISES-RVNISCPE--CTE 181
Query: 567 SFPTSELEKVLPQTILYKYYERKAEEEVAAAYAD-ELVRCPSCSFPALLD--SDVKRFSC 623
F ++ +L +L + YE A D P C + + + + +C
Sbjct: 182 RFNPHDIRLILSDDVLMEKYEEFMLRRWLVADPDCRWCPAPDCGYAVIAFGCASCPKLTC 241
Query: 624 PNPHCRKETCRKCQGLWKEHNGLTCEELAEK--DDIKYRT--------SIEEKMTAARIR 673
C E C C+ +W H TC+ ++ ++ RT S E A I+
Sbjct: 242 GREGCGTEFCYHCKQIW--HPNQTCDAARQERAQSLRLRTIRSSSISYSQESGAAADDIK 299
Query: 674 KCHKCGTGLIKSE--GCNRMSCR-CGAQMCYLCRVSINGYDHFCQHPRSPGAPCQECSRC 730
C +C +IK CN M+C CG + C+LC I+ H SP S C
Sbjct: 300 PCPRCAAYIIKMNDGSCNHMTCAVCGCEFCWLCMKEISDL-----HYLSP-------SGC 347
Query: 731 SLW 733
+ W
Sbjct: 348 TFW 350
>gi|35493782 ring finger protein 19 [Homo sapiens]
Length = 838
Score = 69.3 bits (168), Expect = 1e-11
Identities = 62/243 (25%), Positives = 98/243 (40%), Gaps = 38/243 (15%)
Query: 510 GQLIECRCC---YGEFPFEELTQCADAHLFCKECLIRYAQEAVFGSGKLELSCMEGSCTC 566
G IEC C + + F ++ C H C +CL +Y + + S ++ +SC E CT
Sbjct: 127 GDFIECPLCLLRHSKDRFPDIMTCH--HRSCVDCLRQYLRIEISES-RVNISCPE--CTE 181
Query: 567 SFPTSELEKVLPQTILYKYYERKAEEEVAAAYAD-ELVRCPSCSFPALLD--SDVKRFSC 623
F ++ +L +L + YE A D P C + + + + +C
Sbjct: 182 RFNPHDIRLILSDDVLMEKYEEFMLRRWLVADPDCRWCPAPDCGYAVIAFGCASCPKLTC 241
Query: 624 PNPHCRKETCRKCQGLWKEHNGLTCEELAEK--DDIKYRT--------SIEEKMTAARIR 673
C E C C+ +W H TC+ ++ ++ RT S E A I+
Sbjct: 242 GREGCGTEFCYHCKQIW--HPNQTCDAARQERAQSLRLRTIRSSSISYSQESGAAADDIK 299
Query: 674 KCHKCGTGLIKSE--GCNRMSCR-CGAQMCYLCRVSINGYDHFCQHPRSPGAPCQECSRC 730
C +C +IK CN M+C CG + C+LC I+ H SP S C
Sbjct: 300 PCPRCAAYIIKMNDGSCNHMTCAVCGCEFCWLCMKEISDL-----HYLSP-------SGC 347
Query: 731 SLW 733
+ W
Sbjct: 348 TFW 350
>gi|34577102 ring finger protein 14 isoform 1 [Homo sapiens]
Length = 474
Score = 63.9 bits (154), Expect = 6e-10
Identities = 72/287 (25%), Positives = 115/287 (40%), Gaps = 47/287 (16%)
Query: 475 VQQEQEFYEQKIKEMAEHEDFLLA-LQMNEEQYQK--DGQLIECRCCYGEFPFEELTQCA 531
V QE+ E+ ++++ + + L ++ Q K + +L C C+ E E
Sbjct: 177 VDQEEIVDERAVQDVESLSNLIQEILDFDQAQQIKCFNSKLFLCSICFCEKLGSECMYFL 236
Query: 532 DA-HLFCKECLIRYAQEAVFGSGKLELSCMEGSCTCSFPTSELEKVLPQTILYKYYERKA 590
+ H++CK CL Y + + L+C E C S T K L + L+ Y+R
Sbjct: 237 ECRHVYCKACLKDYFEIQIRDGQVQCLNCPEPKCP-SVATPGQVKELVEAELFARYDRLL 295
Query: 591 EEEVAAAYADELVRCPS--CSFPALLDSDVKRFSCPNPHCRKETCRKCQGLWKEHNGLTC 648
+ AD +V CP C P + + C + C C C+ + H C
Sbjct: 296 LQSSLDLMAD-VVYCPRPCCQLPVMQEPGCTMGICSS--CNFAFCTLCRLTY--HGVSPC 350
Query: 649 EELAEK-----------DDIKYRT------------SIEEKMTAARIRK----CHKCGTG 681
+ AEK D+ R ++EE + + K C CGT
Sbjct: 351 KVTAEKLMDLRNEYLQADEANKRLLDQRYGKRVIQKALEEMESKEWLEKNSKSCPCCGTP 410
Query: 682 LIKSEGCNRMSCR-CGAQMCYLCRVSI---NGYDHFCQHPRSPGAPC 724
+ K +GCN+M+C C C++C S+ N Y HF PG+PC
Sbjct: 411 IEKLDGCNKMTCTGCMQYFCWICMGSLSRANPYKHF----NDPGSPC 453
>gi|34577100 ring finger protein 14 isoform 1 [Homo sapiens]
Length = 474
Score = 63.9 bits (154), Expect = 6e-10
Identities = 72/287 (25%), Positives = 115/287 (40%), Gaps = 47/287 (16%)
Query: 475 VQQEQEFYEQKIKEMAEHEDFLLA-LQMNEEQYQK--DGQLIECRCCYGEFPFEELTQCA 531
V QE+ E+ ++++ + + L ++ Q K + +L C C+ E E
Sbjct: 177 VDQEEIVDERAVQDVESLSNLIQEILDFDQAQQIKCFNSKLFLCSICFCEKLGSECMYFL 236
Query: 532 DA-HLFCKECLIRYAQEAVFGSGKLELSCMEGSCTCSFPTSELEKVLPQTILYKYYERKA 590
+ H++CK CL Y + + L+C E C S T K L + L+ Y+R
Sbjct: 237 ECRHVYCKACLKDYFEIQIRDGQVQCLNCPEPKCP-SVATPGQVKELVEAELFARYDRLL 295
Query: 591 EEEVAAAYADELVRCPS--CSFPALLDSDVKRFSCPNPHCRKETCRKCQGLWKEHNGLTC 648
+ AD +V CP C P + + C + C C C+ + H C
Sbjct: 296 LQSSLDLMAD-VVYCPRPCCQLPVMQEPGCTMGICSS--CNFAFCTLCRLTY--HGVSPC 350
Query: 649 EELAEK-----------DDIKYRT------------SIEEKMTAARIRK----CHKCGTG 681
+ AEK D+ R ++EE + + K C CGT
Sbjct: 351 KVTAEKLMDLRNEYLQADEANKRLLDQRYGKRVIQKALEEMESKEWLEKNSKSCPCCGTP 410
Query: 682 LIKSEGCNRMSCR-CGAQMCYLCRVSI---NGYDHFCQHPRSPGAPC 724
+ K +GCN+M+C C C++C S+ N Y HF PG+PC
Sbjct: 411 IEKLDGCNKMTCTGCMQYFCWICMGSLSRANPYKHF----NDPGSPC 453
>gi|34577098 ring finger protein 14 isoform 1 [Homo sapiens]
Length = 474
Score = 63.9 bits (154), Expect = 6e-10
Identities = 72/287 (25%), Positives = 115/287 (40%), Gaps = 47/287 (16%)
Query: 475 VQQEQEFYEQKIKEMAEHEDFLLA-LQMNEEQYQK--DGQLIECRCCYGEFPFEELTQCA 531
V QE+ E+ ++++ + + L ++ Q K + +L C C+ E E
Sbjct: 177 VDQEEIVDERAVQDVESLSNLIQEILDFDQAQQIKCFNSKLFLCSICFCEKLGSECMYFL 236
Query: 532 DA-HLFCKECLIRYAQEAVFGSGKLELSCMEGSCTCSFPTSELEKVLPQTILYKYYERKA 590
+ H++CK CL Y + + L+C E C S T K L + L+ Y+R
Sbjct: 237 ECRHVYCKACLKDYFEIQIRDGQVQCLNCPEPKCP-SVATPGQVKELVEAELFARYDRLL 295
Query: 591 EEEVAAAYADELVRCPS--CSFPALLDSDVKRFSCPNPHCRKETCRKCQGLWKEHNGLTC 648
+ AD +V CP C P + + C + C C C+ + H C
Sbjct: 296 LQSSLDLMAD-VVYCPRPCCQLPVMQEPGCTMGICSS--CNFAFCTLCRLTY--HGVSPC 350
Query: 649 EELAEK-----------DDIKYRT------------SIEEKMTAARIRK----CHKCGTG 681
+ AEK D+ R ++EE + + K C CGT
Sbjct: 351 KVTAEKLMDLRNEYLQADEANKRLLDQRYGKRVIQKALEEMESKEWLEKNSKSCPCCGTP 410
Query: 682 LIKSEGCNRMSCR-CGAQMCYLCRVSI---NGYDHFCQHPRSPGAPC 724
+ K +GCN+M+C C C++C S+ N Y HF PG+PC
Sbjct: 411 IEKLDGCNKMTCTGCMQYFCWICMGSLSRANPYKHF----NDPGSPC 453
>gi|34577096 ring finger protein 14 isoform 2 [Homo sapiens]
Length = 348
Score = 63.9 bits (154), Expect = 6e-10
Identities = 72/287 (25%), Positives = 115/287 (40%), Gaps = 47/287 (16%)
Query: 475 VQQEQEFYEQKIKEMAEHEDFLLA-LQMNEEQYQK--DGQLIECRCCYGEFPFEELTQCA 531
V QE+ E+ ++++ + + L ++ Q K + +L C C+ E E
Sbjct: 51 VDQEEIVDERAVQDVESLSNLIQEILDFDQAQQIKCFNSKLFLCSICFCEKLGSECMYFL 110
Query: 532 DA-HLFCKECLIRYAQEAVFGSGKLELSCMEGSCTCSFPTSELEKVLPQTILYKYYERKA 590
+ H++CK CL Y + + L+C E C S T K L + L+ Y+R
Sbjct: 111 ECRHVYCKACLKDYFEIQIRDGQVQCLNCPEPKCP-SVATPGQVKELVEAELFARYDRLL 169
Query: 591 EEEVAAAYADELVRCPS--CSFPALLDSDVKRFSCPNPHCRKETCRKCQGLWKEHNGLTC 648
+ AD +V CP C P + + C + C C C+ + H C
Sbjct: 170 LQSSLDLMAD-VVYCPRPCCQLPVMQEPGCTMGICSS--CNFAFCTLCRLTY--HGVSPC 224
Query: 649 EELAEK-----------DDIKYRT------------SIEEKMTAARIRK----CHKCGTG 681
+ AEK D+ R ++EE + + K C CGT
Sbjct: 225 KVTAEKLMDLRNEYLQADEANKRLLDQRYGKRVIQKALEEMESKEWLEKNSKSCPCCGTP 284
Query: 682 LIKSEGCNRMSCR-CGAQMCYLCRVSI---NGYDHFCQHPRSPGAPC 724
+ K +GCN+M+C C C++C S+ N Y HF PG+PC
Sbjct: 285 IEKLDGCNKMTCTGCMQYFCWICMGSLSRANPYKHF----NDPGSPC 327
>gi|4757762 ring finger protein 14 isoform 1 [Homo sapiens]
Length = 474
Score = 63.9 bits (154), Expect = 6e-10
Identities = 72/287 (25%), Positives = 115/287 (40%), Gaps = 47/287 (16%)
Query: 475 VQQEQEFYEQKIKEMAEHEDFLLA-LQMNEEQYQK--DGQLIECRCCYGEFPFEELTQCA 531
V QE+ E+ ++++ + + L ++ Q K + +L C C+ E E
Sbjct: 177 VDQEEIVDERAVQDVESLSNLIQEILDFDQAQQIKCFNSKLFLCSICFCEKLGSECMYFL 236
Query: 532 DA-HLFCKECLIRYAQEAVFGSGKLELSCMEGSCTCSFPTSELEKVLPQTILYKYYERKA 590
+ H++CK CL Y + + L+C E C S T K L + L+ Y+R
Sbjct: 237 ECRHVYCKACLKDYFEIQIRDGQVQCLNCPEPKCP-SVATPGQVKELVEAELFARYDRLL 295
Query: 591 EEEVAAAYADELVRCPS--CSFPALLDSDVKRFSCPNPHCRKETCRKCQGLWKEHNGLTC 648
+ AD +V CP C P + + C + C C C+ + H C
Sbjct: 296 LQSSLDLMAD-VVYCPRPCCQLPVMQEPGCTMGICSS--CNFAFCTLCRLTY--HGVSPC 350
Query: 649 EELAEK-----------DDIKYRT------------SIEEKMTAARIRK----CHKCGTG 681
+ AEK D+ R ++EE + + K C CGT
Sbjct: 351 KVTAEKLMDLRNEYLQADEANKRLLDQRYGKRVIQKALEEMESKEWLEKNSKSCPCCGTP 410
Query: 682 LIKSEGCNRMSCR-CGAQMCYLCRVSI---NGYDHFCQHPRSPGAPC 724
+ K +GCN+M+C C C++C S+ N Y HF PG+PC
Sbjct: 411 IEKLDGCNKMTCTGCMQYFCWICMGSLSRANPYKHF----NDPGSPC 453
>gi|188219577 ring finger protein 19B isoform a [Homo sapiens]
Length = 732
Score = 63.5 bits (153), Expect = 8e-10
Identities = 56/237 (23%), Positives = 96/237 (40%), Gaps = 33/237 (13%)
Query: 513 IECRCCYGEFPFEELTQCADA-HLFCKECLIRYAQEAVFGSGKLELSCMEGSCTCSFPTS 571
+EC C P E + H C++CL Y + + S ++ +SC E C+
Sbjct: 117 VECPLCLVRLPPERAPRLLSCPHRSCRDCLRHYLRLEISES-RVPISCPE--CSERLNPH 173
Query: 572 ELEKVLPQT-ILYKYYERKAEEEVAAAYADELVRCPSCSFPALLD--SDVKRFSCPNPHC 628
++ +L +++KY E +A+ P C + + + + +C C
Sbjct: 174 DIRLLLADPPLMHKYEEFMLRRYLASDPDCRWCPAPDCGYAVIAYGCASCPKLTCEREGC 233
Query: 629 RKETCRKCQGLWKEHNGLTCEELAEK--DDIKYRTSI-------EEKMTAARIRKCHKCG 679
+ E C C+ +W H TC+ ++ ++ RT +E A I+ C +C
Sbjct: 234 QTEFCYHCKQIW--HPNQTCDMARQQRAQTLRVRTKHTSGLSYGQESGPADDIKPCPRCS 291
Query: 680 TGLIKSE--GCNRMSCR-CGAQMCYLCRVSINGYDHFCQHPRSPGAPCQECSRCSLW 733
+IK CN M+C CG + C+LC I+ H SP S C+ W
Sbjct: 292 AYIIKMNDGSCNHMTCAVCGCEFCWLCMKEISDL-----HYLSP-------SGCTFW 336
>gi|188219579 ring finger protein 19B isoform b [Homo sapiens]
Length = 587
Score = 62.4 bits (150), Expect = 2e-09
Identities = 55/236 (23%), Positives = 96/236 (40%), Gaps = 32/236 (13%)
Query: 513 IECRCCYGEFPFEELTQCADA-HLFCKECLIRYAQEAVFGSGKLELSCMEGSCTCSFPTS 571
+EC C P E + H C++CL Y + + S ++ +SC E C+
Sbjct: 117 VECPLCLVRLPPERAPRLLSCPHRSCRDCLRHYLRLEISES-RVPISCPE--CSERLNPH 173
Query: 572 ELEKVLPQT-ILYKYYERKAEEEVAAAYADELVRCPSCSFPALLD--SDVKRFSCPNPHC 628
++ +L +++KY E +A+ P C + + + + +C C
Sbjct: 174 DIRLLLADPPLMHKYEEFMLRRYLASDPDCRWCPAPDCGYAVIAYGCASCPKLTCEREGC 233
Query: 629 RKETCRKCQGLWKEHNGLTCEELAEK--DDIKYRT------SIEEKMTAARIRKCHKCGT 680
+ E C C+ +W H TC+ ++ ++ RT S ++ I+ C +C
Sbjct: 234 QTEFCYHCKQIW--HPNQTCDMARQQRAQTLRVRTKHTSGLSYGQESGPDDIKPCPRCSA 291
Query: 681 GLIKSE--GCNRMSCR-CGAQMCYLCRVSINGYDHFCQHPRSPGAPCQECSRCSLW 733
+IK CN M+C CG + C+LC I+ H SP S C+ W
Sbjct: 292 YIIKMNDGSCNHMTCAVCGCEFCWLCMKEISDL-----HYLSP-------SGCTFW 335
>gi|187761373 ariadne ubiquitin-conjugating enzyme E2 binding
protein homolog 1 [Homo sapiens]
Length = 557
Score = 62.4 bits (150), Expect = 2e-09
Identities = 64/268 (23%), Positives = 100/268 (37%), Gaps = 38/268 (14%)
Query: 500 QMNEEQYQKDGQLIECRCCYGEFPFEELTQCADAHLFCKECLIRYAQEAVFGSGKLE-LS 558
QMN +D + C+ CY +P T H FC +C Y + G + +S
Sbjct: 174 QMNTRSSAQD---MPCQICYLNYPNSYFTGLECGHKFCMQCWSEYLTTKIMEEGMGQTIS 230
Query: 559 CMEGSCTCSFPTSELEKVLPQT-ILYKYYERKAEEEVAAAYADELVRCPSCSFPALLD-S 616
C C + + +++ + + KY V + P C +
Sbjct: 231 CPAHGCDILVDDNTVMRLITDSKVKLKYQHLITNSFVECNRLLKWCPAPDCHHVVKVQYP 290
Query: 617 DVKRFSCPNPHCRKETCRKCQGLWKEHNGLTCEELAE---KDDIKYRTSIEEKMTAARIR 673
D K C C ++ C C W H+ + C+ L + K D TS AA +
Sbjct: 291 DAKPVRCK---CGRQFCFNCGENW--HDPVKCKWLKKWIKKCDDDSETS---NWIAANTK 342
Query: 674 KCHKCGTGLIKSEGCNRMSCR---CGAQMCYLCRVSINGYDHFCQHPRSP-GAPCQECSR 729
+C KC + K GCN M CR C A+ C++ C P P G+ C+R
Sbjct: 343 ECPKCHVTIEKDGGCNHMVCRNQNCKAEFCWV-----------CLGPWEPHGSAWYNCNR 391
Query: 730 CSLWTDPTEDDEKLIEEIQKEAEEEQKR 757
+ EDD K + Q+ + +R
Sbjct: 392 YN------EDDAKAARDAQERSRAALQR 413
Score = 40.0 bits (92), Expect = 0.009
Identities = 25/90 (27%), Positives = 32/90 (35%), Gaps = 3/90 (3%)
Query: 591 EEEVAAAYADELVRCPSCSFPALLDSDVKRFSCPNPHCRKETCRKCQGLWKEHNG--LTC 648
+ E + A CP C D C N +C+ E C C G W+ H C
Sbjct: 330 DSETSNWIAANTKECPKCHVTIEKDGGCNHMVCRNQNCKAEFCWVCLGPWEPHGSAWYNC 389
Query: 649 EELAEKDDIKYRTSIEEKMTAARIRKCHKC 678
E DD K +E+ AA R C
Sbjct: 390 NRYNE-DDAKAARDAQERSRAALQRYLFYC 418
>gi|5453557 ariadne homolog 2 [Homo sapiens]
Length = 493
Score = 61.6 bits (148), Expect = 3e-09
Identities = 46/193 (23%), Positives = 75/193 (38%), Gaps = 9/193 (4%)
Query: 515 CRCCYGEFPFEELTQCADAHLFCKECLIRYAQEAVFGSGKLELSCMEGSCTCSFPTSELE 574
C C E L A H FC+ C ++ V + +SCM C P +
Sbjct: 139 CAVCMQFVRKENLLSLACQHQFCRSCWEQHCSVLVKDGVGVGVSCMAQDCPLRTPEDFVF 198
Query: 575 KVLPQTILYKYYERKAEEEVAAAYADELVRCPSCSFPALL---DSDVKRFSCPNPHCRKE 631
+LP L + Y R + ++ +L CP P ++ + +R C C +
Sbjct: 199 PLLPNEELREKYRRYLFRDYVESHY-QLQLCPGADCPMVIRVQEPRARRVQC--NRCNEV 255
Query: 632 TCRKCQGLWKEHNGLTCEELAEKDDIKYRTSIEEKMTAARIRKCHKCGTGLIKSEGCNRM 691
C KC+ ++ H C + + S +A + C KC + K+ GCN M
Sbjct: 256 FCFKCRQMY--HAPTDCATIRKWLTKCADDSETANYISAHTKDCPKCNICIEKNGGCNHM 313
Query: 692 SC-RCGAQMCYLC 703
C +C C++C
Sbjct: 314 QCSKCKHDFCWMC 326
Score = 30.8 bits (68), Expect = 5.7
Identities = 19/77 (24%), Positives = 28/77 (36%), Gaps = 5/77 (6%)
Query: 584 KYYERKAEEEVAAAYADELVR-CPSCSFPALLDSDVKRFSCPNPHCRKETCRKCQGLWKE 642
K+ + A++ A Y + CP C+ + C C+ + C C G WK
Sbjct: 275 KWLTKCADDSETANYISAHTKDCPKCNICIEKNGGCNHMQCSK--CKHDFCWMCLGDWKT 332
Query: 643 HNG--LTCEELAEKDDI 657
H C E DI
Sbjct: 333 HGSEYYECSRYKENPDI 349
>gi|22749145 ring finger protein 217 [Homo sapiens]
Length = 275
Score = 58.2 bits (139), Expect = 3e-08
Identities = 46/169 (27%), Positives = 71/169 (42%), Gaps = 29/169 (17%)
Query: 554 KLELSCMEGSCTCSFPTSELEKVLPQTILYKYYERKAEEEVAAAYADELVR-------CP 606
K++L +E C P +E + L +T + Y E+ + Y EL R CP
Sbjct: 2 KVQLGQVEIKC----PITECFEFLEETTVV--YNLTHEDSIKYKYFLELGRIDSSTKPCP 55
Query: 607 SCS----------FPALLDSDVK-RFSCPNPHCRKETCRKCQGLWKEHNGLTCEELAEKD 655
C P S+ K + CP C+ C KC W H G+ C+E + D
Sbjct: 56 QCKHFTTFKKKGHIPTPSRSESKYKIQCPT--CQFVWCFKCHSPW--HEGVNCKEYKKGD 111
Query: 656 DIKYRTSIEEKMTAARIRKCHKCGTGLIKSEGCNRMSC-RCGAQMCYLC 703
+ + E + +KC KC + ++EGC+ M+C +C CY C
Sbjct: 112 KLLRHWASEIEHGQRNAQKCPKCKIHIQRTEGCDHMTCSQCNTNFCYRC 160
>gi|50284696 IBR domain containing 2 [Homo sapiens]
Length = 303
Score = 54.7 bits (130), Expect = 4e-07
Identities = 55/225 (24%), Positives = 93/225 (41%), Gaps = 37/225 (16%)
Query: 512 LIECRCCYGEFPFEELTQCADAH-LFCKECLIRYAQEAVFGSGKLELSCMEGSCTC--SF 568
LI C+ C E +++T + +FC CL +Y Q A+ ++C + C +
Sbjct: 27 LITCKLCLCEQSLDKMTTLQECQCIFCTACLKQYMQLAIREGCGSPITCPDMVCLNHGTL 86
Query: 569 PTSELEKVLPQTILYKYYERKAEEEVA-------AAYADELVRCPSCSF----PALLDSD 617
+E+ ++P Y K E EV AD CP S P L++
Sbjct: 87 QEAEIACLVPVDQFQLYQRLKFEREVHLDPYRTWCPVADCQTVCPVASSDPGQPVLVE-- 144
Query: 618 VKRFSCPNPHCRKETCRKCQGLWKEHNGLTCEE-----LAEKDDIKYRTSIEEKMTAARI 672
CP+ C + C C+ W H ++C + L + + T E A I
Sbjct: 145 -----CPS--CHLKFCSCCKDAW--HAEVSCRDSQPIVLPTEHRALFGTDAE-----API 190
Query: 673 RKCHKCGTGLIKSEGCNRMSCR-CGAQMCYLCRVSINGYDHFCQH 716
++C C + ++EGC +M C+ C C+ C +++ D F +H
Sbjct: 191 KQCPVCRVYIERNEGCAQMMCKNCKHTFCWYCLQNLDN-DIFLRH 234
>gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo
sapiens]
Length = 2715
Score = 50.1 bits (118), Expect = 9e-06
Identities = 30/98 (30%), Positives = 50/98 (51%), Gaps = 7/98 (7%)
Query: 738 EDDEKLIEEIQKEAEEEQKRKNGENTFKRIGPPLEKPVEKVQRVEALPRPV--PQNLPQP 795
+ ++KL +E +++ EEE+K K GE +R P + + + P P+ P P P
Sbjct: 356 KQEQKLDDEEEEKKEEEEKDKEGEEKEERAVAEEMMPAAEKEEAKLPPPPLTPPAPSPPP 415
Query: 796 QMPPYAFAHPPFPLPPVRPVFNNFPLNMGPIPAPYVPP 833
+PP + + PP PP P P++ P+P+P PP
Sbjct: 416 PLPPPSTSPPPPLCPPPPP-----PVSPPPLPSPPPPP 448
>gi|157168329 formin 1 [Homo sapiens]
Length = 1196
Score = 44.7 bits (104), Expect = 4e-04
Identities = 26/56 (46%), Positives = 29/56 (51%), Gaps = 5/56 (8%)
Query: 785 PRPVPQNL----PQPQMPPYAFAHPPFPLPPVRPVFNNFPLNMGPIPAPYVPPLPN 836
P P+P L P P MPP + A PP P PP P P + GP P P PPLPN
Sbjct: 655 PPPLPSGLGSLSPAPPMPPVS-AGPPLPPPPPPPPPLPPPSSAGPPPPPPPPPLPN 709
Score = 37.0 bits (84), Expect = 0.079
Identities = 24/64 (37%), Positives = 28/64 (43%), Gaps = 5/64 (7%)
Query: 774 PVEKVQRVEALPRPVPQNLPQPQMPPYAFAHPPFPLPPVRPVFNNFPLNMGPIPAPYVPP 833
P+ V LP P P P P +PP + A PP P PP P N P P P PP
Sbjct: 670 PMPPVSAGPPLPPPPP---PPPPLPPPSSAGPPPPPPP--PPLPNSPAPPNPGGPPPAPP 724
Query: 834 LPNV 837
P +
Sbjct: 725 PPGL 728
>gi|169790973 parkin isoform 3 [Homo sapiens]
Length = 316
Score = 44.3 bits (103), Expect = 5e-04
Identities = 31/110 (28%), Positives = 39/110 (35%), Gaps = 25/110 (22%)
Query: 536 FCKECLIRYAQEAVFGSGKLELSCMEGSCTCSFPTSELEKVLPQTILYKYYERKAEEEVA 595
FC+EC Y EG C+ F S T Y+ ER AE+
Sbjct: 215 FCRECKEAYH---------------EGECSAVFEASGTT-----TQAYRVDERAAEQARW 254
Query: 596 AAYADELVR-----CPSCSFPALLDSDVKRFSCPNPHCRKETCRKCQGLW 640
A + E ++ CP C P + CP P CR E C C W
Sbjct: 255 EAASKETIKKTTKPCPRCHVPVEKNGGCMHMKCPQPQCRLEWCWNCGCEW 304
Score = 42.4 bits (98), Expect = 0.002
Identities = 44/198 (22%), Positives = 75/198 (37%), Gaps = 23/198 (11%)
Query: 529 QCADAHLFCKECLIRYAQEAVFGSGKLELSCMEGS--CTCSFPTSELEKVLPQTIL---- 582
QC H+ C +C Y + + + S C P S ++++ IL
Sbjct: 103 QCNSRHVICLDCFHLYCVTRLNDRQFVHDPQLGYSLPCVAGCPNSLIKELHHFRILGEEQ 162
Query: 583 YKYYERKAEEEVAAAYADELVRCPSCSFPALLDSDVKRFSCPNPH---CRKETCRKCQGL 639
Y Y++ EE L P C L + D ++ +C + C CR+C+
Sbjct: 163 YNRYQQYGAEECVLQMGGVLCPRPGCGAGLLPEPDQRKVTCEGGNGLGCGFAFCRECKEA 222
Query: 640 WKEH--------NGLTCE--ELAEKDDIKYRTSIEEKMTAARIRK-CHKCGTGLIKSEGC 688
+ E +G T + + E+ + R K T + K C +C + K+ GC
Sbjct: 223 YHEGECSAVFEASGTTTQAYRVDERAAEQARWEAASKETIKKTTKPCPRCHVPVEKNGGC 282
Query: 689 NRMSC---RCGAQMCYLC 703
M C +C + C+ C
Sbjct: 283 MHMKCPQPQCRLEWCWNC 300
>gi|169790971 parkin isoform 2 [Homo sapiens]
Length = 437
Score = 44.3 bits (103), Expect = 5e-04
Identities = 31/110 (28%), Positives = 39/110 (35%), Gaps = 25/110 (22%)
Query: 536 FCKECLIRYAQEAVFGSGKLELSCMEGSCTCSFPTSELEKVLPQTILYKYYERKAEEEVA 595
FC+EC Y EG C+ F S T Y+ ER AE+
Sbjct: 336 FCRECKEAYH---------------EGECSAVFEASGTT-----TQAYRVDERAAEQARW 375
Query: 596 AAYADELVR-----CPSCSFPALLDSDVKRFSCPNPHCRKETCRKCQGLW 640
A + E ++ CP C P + CP P CR E C C W
Sbjct: 376 EAASKETIKKTTKPCPRCHVPVEKNGGCMHMKCPQPQCRLEWCWNCGCEW 425
Score = 42.4 bits (98), Expect = 0.002
Identities = 44/198 (22%), Positives = 75/198 (37%), Gaps = 23/198 (11%)
Query: 529 QCADAHLFCKECLIRYAQEAVFGSGKLELSCMEGS--CTCSFPTSELEKVLPQTIL---- 582
QC H+ C +C Y + + + S C P S ++++ IL
Sbjct: 224 QCNSRHVICLDCFHLYCVTRLNDRQFVHDPQLGYSLPCVAGCPNSLIKELHHFRILGEEQ 283
Query: 583 YKYYERKAEEEVAAAYADELVRCPSCSFPALLDSDVKRFSCPNPH---CRKETCRKCQGL 639
Y Y++ EE L P C L + D ++ +C + C CR+C+
Sbjct: 284 YNRYQQYGAEECVLQMGGVLCPRPGCGAGLLPEPDQRKVTCEGGNGLGCGFAFCRECKEA 343
Query: 640 WKEH--------NGLTCE--ELAEKDDIKYRTSIEEKMTAARIRK-CHKCGTGLIKSEGC 688
+ E +G T + + E+ + R K T + K C +C + K+ GC
Sbjct: 344 YHEGECSAVFEASGTTTQAYRVDERAAEQARWEAASKETIKKTTKPCPRCHVPVEKNGGC 403
Query: 689 NRMSC---RCGAQMCYLC 703
M C +C + C+ C
Sbjct: 404 MHMKCPQPQCRLEWCWNC 421
>gi|169790969 parkin isoform 1 [Homo sapiens]
Length = 465
Score = 44.3 bits (103), Expect = 5e-04
Identities = 31/110 (28%), Positives = 39/110 (35%), Gaps = 25/110 (22%)
Query: 536 FCKECLIRYAQEAVFGSGKLELSCMEGSCTCSFPTSELEKVLPQTILYKYYERKAEEEVA 595
FC+EC Y EG C+ F S T Y+ ER AE+
Sbjct: 364 FCRECKEAYH---------------EGECSAVFEASGTT-----TQAYRVDERAAEQARW 403
Query: 596 AAYADELVR-----CPSCSFPALLDSDVKRFSCPNPHCRKETCRKCQGLW 640
A + E ++ CP C P + CP P CR E C C W
Sbjct: 404 EAASKETIKKTTKPCPRCHVPVEKNGGCMHMKCPQPQCRLEWCWNCGCEW 453
Score = 42.4 bits (98), Expect = 0.002
Identities = 44/198 (22%), Positives = 75/198 (37%), Gaps = 23/198 (11%)
Query: 529 QCADAHLFCKECLIRYAQEAVFGSGKLELSCMEGS--CTCSFPTSELEKVLPQTIL---- 582
QC H+ C +C Y + + + S C P S ++++ IL
Sbjct: 252 QCNSRHVICLDCFHLYCVTRLNDRQFVHDPQLGYSLPCVAGCPNSLIKELHHFRILGEEQ 311
Query: 583 YKYYERKAEEEVAAAYADELVRCPSCSFPALLDSDVKRFSCPNPH---CRKETCRKCQGL 639
Y Y++ EE L P C L + D ++ +C + C CR+C+
Sbjct: 312 YNRYQQYGAEECVLQMGGVLCPRPGCGAGLLPEPDQRKVTCEGGNGLGCGFAFCRECKEA 371
Query: 640 WKEH--------NGLTCE--ELAEKDDIKYRTSIEEKMTAARIRK-CHKCGTGLIKSEGC 688
+ E +G T + + E+ + R K T + K C +C + K+ GC
Sbjct: 372 YHEGECSAVFEASGTTTQAYRVDERAAEQARWEAASKETIKKTTKPCPRCHVPVEKNGGC 431
Query: 689 NRMSC---RCGAQMCYLC 703
M C +C + C+ C
Sbjct: 432 MHMKCPQPQCRLEWCWNC 449
>gi|215820635 protein phosphatase 1, regulatory subunit 13 like
[Homo sapiens]
Length = 828
Score = 43.9 bits (102), Expect = 6e-04
Identities = 33/102 (32%), Positives = 43/102 (42%), Gaps = 18/102 (17%)
Query: 760 GENTFKRIGPPLEKPVEKVQRVEALPRPVPQNLPQPQMPPYAFAHPPFPLP-PVRPVFNN 818
G F R PP +P + P+P PQ+ PQPQ+PP P P P P P
Sbjct: 394 GSPLFTRAPPPKLQP-------QPQPQPQPQSQPQPQLPPQPQTQPQTPTPAPQHPQQTW 446
Query: 819 FPLNMG-PIPAPYVPPLPNVR---------VNYDFGPIHMPL 850
P+N G P P + P P + + D GP+ PL
Sbjct: 447 PPVNEGPPKPPTELEPEPEIEGLLTPVLEAGDVDEGPVARPL 488
>gi|63003907 protein phosphatase 1, regulatory subunit 13 like [Homo
sapiens]
Length = 828
Score = 43.9 bits (102), Expect = 6e-04
Identities = 33/102 (32%), Positives = 43/102 (42%), Gaps = 18/102 (17%)
Query: 760 GENTFKRIGPPLEKPVEKVQRVEALPRPVPQNLPQPQMPPYAFAHPPFPLP-PVRPVFNN 818
G F R PP +P + P+P PQ+ PQPQ+PP P P P P P
Sbjct: 394 GSPLFTRAPPPKLQP-------QPQPQPQPQSQPQPQLPPQPQTQPQTPTPAPQHPQQTW 446
Query: 819 FPLNMG-PIPAPYVPPLPNVR---------VNYDFGPIHMPL 850
P+N G P P + P P + + D GP+ PL
Sbjct: 447 PPVNEGPPKPPTELEPEPEIEGLLTPVLEAGDVDEGPVARPL 488
>gi|224451135 splicing factor, arginine/serine-rich 15 isoform 3
[Homo sapiens]
Length = 1125
Score = 42.0 bits (97), Expect = 0.002
Identities = 33/107 (30%), Positives = 45/107 (42%), Gaps = 8/107 (7%)
Query: 747 IQKEAEEEQKRKNG-ENTFKRIGPPLEKPVEKVQRVEALPRPVPQNLPQPQMPPYAFAHP 805
I K+ E E + G E + P+ KP+ V +P P P +P PQ+PP+ P
Sbjct: 633 IPKKPENEVAQNGGAETSHTEPVSPIPKPLPVP--VPPIPVPAPITVPPPQVPPHQPGPP 690
Query: 806 ---PFPLPPVRPVFNNFPLNMGPIPAPYVPPLPNVRVNYDFGPIHMP 849
P P P GP P PP P +R F P+H+P
Sbjct: 691 VVGALQPPAFTPPLGIPPPGFGPGVPPPPPPPPFLRPG--FNPMHLP 735
>gi|224451133 splicing factor, arginine/serine-rich 15 isoform 2
[Homo sapiens]
Length = 1132
Score = 42.0 bits (97), Expect = 0.002
Identities = 33/107 (30%), Positives = 45/107 (42%), Gaps = 8/107 (7%)
Query: 747 IQKEAEEEQKRKNG-ENTFKRIGPPLEKPVEKVQRVEALPRPVPQNLPQPQMPPYAFAHP 805
I K+ E E + G E + P+ KP+ V +P P P +P PQ+PP+ P
Sbjct: 618 IPKKPENEVAQNGGAETSHTEPVSPIPKPLPVP--VPPIPVPAPITVPPPQVPPHQPGPP 675
Query: 806 ---PFPLPPVRPVFNNFPLNMGPIPAPYVPPLPNVRVNYDFGPIHMP 849
P P P GP P PP P +R F P+H+P
Sbjct: 676 VVGALQPPAFTPPLGIPPPGFGPGVPPPPPPPPFLRPG--FNPMHLP 720
>gi|40789229 splicing factor, arginine/serine-rich 15 isoform 1
[Homo sapiens]
Length = 1147
Score = 42.0 bits (97), Expect = 0.002
Identities = 33/107 (30%), Positives = 45/107 (42%), Gaps = 8/107 (7%)
Query: 747 IQKEAEEEQKRKNG-ENTFKRIGPPLEKPVEKVQRVEALPRPVPQNLPQPQMPPYAFAHP 805
I K+ E E + G E + P+ KP+ V +P P P +P PQ+PP+ P
Sbjct: 633 IPKKPENEVAQNGGAETSHTEPVSPIPKPLPVP--VPPIPVPAPITVPPPQVPPHQPGPP 690
Query: 806 ---PFPLPPVRPVFNNFPLNMGPIPAPYVPPLPNVRVNYDFGPIHMP 849
P P P GP P PP P +R F P+H+P
Sbjct: 691 VVGALQPPAFTPPLGIPPPGFGPGVPPPPPPPPFLRPG--FNPMHLP 735
>gi|117414137 retinitis pigmentosa 1-like 1 [Homo sapiens]
Length = 2400
Score = 41.2 bits (95), Expect = 0.004
Identities = 58/258 (22%), Positives = 100/258 (38%), Gaps = 30/258 (11%)
Query: 50 APQQHEEEDLDDDVILTEDDSEDDYGEFLDLGPPGISEFTKPSGQTEREPKPGPSHNQAA 109
A ++ + E D + + E ++++ GE P + P + E + + ++
Sbjct: 1966 AEEEAQPESEDVEALEVEVETQEAEGE----AQPESEDVEAPEAEGEMQEAEEEAQPESD 2021
Query: 110 NDIVNPRSEQKVIILEEGSLLYTESDPL-ETQNQSSEDSETELLSNLGESAALADDQAIE 168
P+SE + EG TE D E+ + ++E E GE ++
Sbjct: 2022 GVEAQPKSEGEEAQEVEGETQKTEGDAQPESDGVEAPEAEEEAQEAEGE---------VQ 2072
Query: 169 EDCWLDHPYFQSLNQQPREITNQ-----VVPQERQPEAELGRLLFQHEFPGPAFPRPEPQ 223
E HP + ++ Q E Q V E + EA+ + E G A +P+
Sbjct: 2073 EAEGEAHPESEDVDAQEAEGEAQPESEGVEAPEAEGEAQKAEGIEAPETEGEA----QPE 2128
Query: 224 QGGISGPSSPQPAHPLGEFEDQQLASDDEEPG----PAFPMQESQEPNLENIWGQEA--- 276
GI P + A P E + Q A + +P A +E +P LE + EA
Sbjct: 2129 SEGIEAPEAEGEAQPESEGVEAQDAEGEAQPESEGIEAQEAEEEAQPELEGVEAPEAEGE 2188
Query: 277 AEVDQELVELLVKETEAR 294
A+ + E +E E EA+
Sbjct: 2189 AQPESEGIEAPEAEGEAQ 2206
Score = 34.3 bits (77), Expect = 0.51
Identities = 52/239 (21%), Positives = 88/239 (36%), Gaps = 22/239 (9%)
Query: 67 EDDSEDDYGEFLDLGPPGISEFTKPSGQTEREPKPGPSHNQAANDIVNPRSEQKVIILEE 126
E D+++ GE P + P + E +P+ + D+ P +E +V E
Sbjct: 1857 EGDAQEAEGE----AQPESEDVEAPEAEGEAQPE--------SEDVETPEAEWEVQPESE 1904
Query: 127 GSLLYTESDPLETQNQSSEDSETELLSNLGESAALADDQAIEEDCWLDHPYFQSLNQQPR 186
G+ + + +S E ETE GE ++ +E +
Sbjct: 1905 GAEAPEAEKEAQPETESVEALETE-----GEDEPESEGAEAQEAEEAAQEAEGQTQPESE 1959
Query: 187 EITNQVVPQERQPEAELGRLLFQHEFPGPAFPRPEPQQGGISGPSSPQPAHPLGEFEDQQ 246
I +Q +E QPE+E L A +P+ + P + E+ Q
Sbjct: 1960 VIESQEAEEEAQPESEDVEALEVEVETQEAEGEAQPESEDVEAPEAEGEMQEAE--EEAQ 2017
Query: 247 LASDDEEPGPAFPMQESQEPNLENIWGQEAAEVDQELVELLVKETEARFPDVANGFIEE 305
SD E P +E+QE E + A+ + + VE E EA+ A G ++E
Sbjct: 2018 PESDGVEAQPKSEGEEAQEVEGETQKTEGDAQPESDGVEAPEAEEEAQ---EAEGEVQE 2073
Score = 31.6 bits (70), Expect = 3.3
Identities = 48/218 (22%), Positives = 81/218 (37%), Gaps = 29/218 (13%)
Query: 49 PAPQQHEEEDLDDDVILTEDDSEDDYGEFLDLGPPGISEFTKPSGQTEREPKPGPSHNQA 108
P + E ++++ + TE D++ + G+ + + E E + Q
Sbjct: 2027 PKSEGEEAQEVEGETQKTEGDAQPE--------SDGVE-----APEAEEEAQEAEGEVQE 2073
Query: 109 ANDIVNPRSEQKVIILEEGSLLYTESDPLETQNQSSEDSETELLSNLGESAALADDQAIE 168
A +P SE EG E+ P E++ + ++E E G A + +A
Sbjct: 2074 AEGEAHPESEDVDAQEAEG-----EAQP-ESEGVEAPEAEGEAQKAEGIEAPETEGEAQP 2127
Query: 169 EDCWLDHPYFQSLNQQPRE-ITNQVVPQERQPEAE-----LGRLLFQHEFPGPAFPRPE- 221
E ++ P + Q E + Q E QPE+E Q E G P E
Sbjct: 2128 ESEGIEAPEAEGEAQPESEGVEAQDAEGEAQPESEGIEAQEAEEEAQPELEGVEAPEAEG 2187
Query: 222 ---PQQGGISGPSSPQPAHPLGEFEDQQLASDDEEPGP 256
P+ GI P + A P E + A ++ +P P
Sbjct: 2188 EAQPESEGIEAPEAEGEAQPELEGVEAPEAEEEAQPEP 2225
>gi|239753435 PREDICTED: hypothetical protein XP_002345651 [Homo
sapiens]
Length = 218
Score = 40.8 bits (94), Expect = 0.005
Identities = 24/66 (36%), Positives = 29/66 (43%), Gaps = 2/66 (3%)
Query: 769 PPLEKPVEKVQRVEALPRPVPQNLPQPQMPPYAFAHPPFPLPPVRPVFNNFPLNMGPIPA 828
PP P K R PRP+P N P+P +PP P PLPP RP PL +
Sbjct: 24 PPPPLPPRKPPRPPKPPRPLPPNPPRPPLPPPRPPKP--PLPPPRPPKPPSPLGLAQSKV 81
Query: 829 PYVPPL 834
P +
Sbjct: 82 TLFPSI 87
Score = 33.5 bits (75), Expect = 0.87
Identities = 20/46 (43%), Positives = 22/46 (47%), Gaps = 3/46 (6%)
Query: 793 PQPQMPPYAFAHPPFPLPPVRPVFNNFPLNMGPIPAPYVPPLPNVR 838
P P +PP PP P P RP+ N P P P P PPLP R
Sbjct: 24 PPPPLPP---RKPPRPPKPPRPLPPNPPRPPLPPPRPPKPPLPPPR 66
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.135 0.417
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 41,366,800
Number of Sequences: 37866
Number of extensions: 2440479
Number of successful extensions: 15972
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 67
Number of HSP's successfully gapped in prelim test: 416
Number of HSP's that attempted gapping in prelim test: 13738
Number of HSP's gapped (non-prelim): 2171
length of query: 866
length of database: 18,247,518
effective HSP length: 111
effective length of query: 755
effective length of database: 14,044,392
effective search space: 10603515960
effective search space used: 10603515960
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.