Guide to the Human Genome
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Search of human proteins with 46049125

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|46049125 myosin binding protein C, slow type isoform 2 [Homo
sapiens]
         (1148 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|46049125 myosin binding protein C, slow type isoform 2 [Homo ...  2333   0.0  
gi|45976288 myosin binding protein C, slow type isoform 1 [Homo ...  2331   0.0  
gi|46049110 myosin binding protein C, slow type isoform 4 [Homo ...  2270   0.0  
gi|46049119 myosin binding protein C, slow type isoform 3 [Homo ...  2258   0.0  
gi|133908641 myosin binding protein C, fast type [Homo sapiens]      1164   0.0  
gi|148596957 myosin binding protein C, cardiac [Homo sapiens]        1147   0.0  
gi|55956914 myosin binding protein H [Homo sapiens]                   458   e-128
gi|194018539 myosin binding protein H-like [Homo sapiens]             375   e-103
gi|253970427 immunoglobulin superfamily, member 22 [Homo sapiens]     303   5e-82
gi|110349719 titin isoform N2-A [Homo sapiens]                        299   9e-81
gi|110349717 titin isoform novex-2 [Homo sapiens]                     299   9e-81
gi|110349713 titin isoform novex-1 [Homo sapiens]                     299   9e-81
gi|110349715 titin isoform N2-B [Homo sapiens]                        299   9e-81
gi|148839296 immunoglobulin-like and fibronectin type III domain...   249   1e-65
gi|110349721 titin isoform novex-3 [Homo sapiens]                     139   2e-32
gi|156104903 myomesin 2 [Homo sapiens]                                137   6e-32
gi|140560917 myomesin 1 isoform b [Homo sapiens]                      132   2e-30
gi|58331253 obscurin, cytoskeletal calmodulin and titin-interact...   129   2e-29
gi|148833506 obscurin, cytoskeletal calmodulin and titin-interac...   129   2e-29
gi|118572606 hemicentin 1 [Homo sapiens]                              123   9e-28
gi|140560919 myomesin 1 isoform a [Homo sapiens]                      117   5e-26
gi|144226847 obscurin-like 1 [Homo sapiens]                           116   1e-25
gi|20127422 Down syndrome cell adhesion molecule isoform CHD2-42...   116   1e-25
gi|155969693 myomesin family, member 3 [Homo sapiens]                 114   7e-25
gi|157785645 SPEG complex locus [Homo sapiens]                        112   2e-24
gi|21359935 Down syndrome cell adhesion molecule like 1 [Homo sa...   111   4e-24
gi|19743806 roundabout 1 isoform b [Homo sapiens]                     105   3e-22
gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens]                   105   3e-22
gi|4506569 roundabout 1 isoform a [Homo sapiens]                      105   3e-22
gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens]                   104   4e-22

>gi|46049125 myosin binding protein C, slow type isoform 2 [Homo
            sapiens]
          Length = 1148

 Score = 2333 bits (6046), Expect = 0.0
 Identities = 1148/1148 (100%), Positives = 1148/1148 (100%)

Query: 1    MPEPTKKEENEVPAPAPPPEEPSKEKEAGTTPAKDEEEVSPPSALPPGLGSRALERKDSD 60
            MPEPTKKEENEVPAPAPPPEEPSKEKEAGTTPAKDEEEVSPPSALPPGLGSRALERKDSD
Sbjct: 1    MPEPTKKEENEVPAPAPPPEEPSKEKEAGTTPAKDEEEVSPPSALPPGLGSRALERKDSD 60

Query: 61   WTLVETPPGEEQAKQNANSQLSILFIEKPQGGTVKVGEDITFIAKVKAEDLLRKPTIKWF 120
            WTLVETPPGEEQAKQNANSQLSILFIEKPQGGTVKVGEDITFIAKVKAEDLLRKPTIKWF
Sbjct: 61   WTLVETPPGEEQAKQNANSQLSILFIEKPQGGTVKVGEDITFIAKVKAEDLLRKPTIKWF 120

Query: 121  KGKWMDLASKAGKHLQLKETFERHSRVYTFEMQIIKAKDNFAGNYRCEVTYKDKFDSCSF 180
            KGKWMDLASKAGKHLQLKETFERHSRVYTFEMQIIKAKDNFAGNYRCEVTYKDKFDSCSF
Sbjct: 121  KGKWMDLASKAGKHLQLKETFERHSRVYTFEMQIIKAKDNFAGNYRCEVTYKDKFDSCSF 180

Query: 181  DLEVHESTGTTPNIDIRSAFKRSGEGQEDAGELDFSGLLKRREVKQQEEEPQVDVWELLK 240
            DLEVHESTGTTPNIDIRSAFKRSGEGQEDAGELDFSGLLKRREVKQQEEEPQVDVWELLK
Sbjct: 181  DLEVHESTGTTPNIDIRSAFKRSGEGQEDAGELDFSGLLKRREVKQQEEEPQVDVWELLK 240

Query: 241  NAKPSEYEKIAFQYGITDLRGMLKRLKRMRREEKKSAAFAKILDPAYQVDKGGRVRFVVE 300
            NAKPSEYEKIAFQYGITDLRGMLKRLKRMRREEKKSAAFAKILDPAYQVDKGGRVRFVVE
Sbjct: 241  NAKPSEYEKIAFQYGITDLRGMLKRLKRMRREEKKSAAFAKILDPAYQVDKGGRVRFVVE 300

Query: 301  LADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTEL 360
            LADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTEL
Sbjct: 301  LADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTEL 360

Query: 361  FVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEG 420
            FVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEG
Sbjct: 361  FVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEG 420

Query: 421  KKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCE 480
            KKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCE
Sbjct: 421  KKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCE 480

Query: 481  ISENIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAK 540
            ISENIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAK
Sbjct: 481  ISENIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAK 540

Query: 541  VHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRT 600
            VHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRT
Sbjct: 541  VHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRT 600

Query: 601  ESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDW 660
            ESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDW
Sbjct: 601  ESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDW 660

Query: 661  CIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIF 720
            CIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIF
Sbjct: 661  CIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIF 720

Query: 721  AVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLE 780
            AVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLE
Sbjct: 721  AVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLE 780

Query: 781  YCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEI 840
            YCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEI
Sbjct: 781  YCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEI 840

Query: 841  IEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETD 900
            IEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETD
Sbjct: 841  IEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETD 900

Query: 901  TIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWT 960
            TIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWT
Sbjct: 901  TIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWT 960

Query: 961  PPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGL 1020
            PPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGL
Sbjct: 961  PPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGL 1020

Query: 1021 SEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGN 1080
            SEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGN
Sbjct: 1021 SEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGN 1080

Query: 1081 PKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECK 1140
            PKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECK
Sbjct: 1081 PKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECK 1140

Query: 1141 LEVKVIAQ 1148
            LEVKVIAQ
Sbjct: 1141 LEVKVIAQ 1148


>gi|45976288 myosin binding protein C, slow type isoform 1 [Homo
            sapiens]
          Length = 1171

 Score = 2331 bits (6040), Expect = 0.0
 Identities = 1147/1148 (99%), Positives = 1147/1148 (99%)

Query: 1    MPEPTKKEENEVPAPAPPPEEPSKEKEAGTTPAKDEEEVSPPSALPPGLGSRALERKDSD 60
            MPEPTKKEENEVPAPAPPPEEPSKEKEAGTTPAKDEEEVSPPSALPPGLGSRALERKDSD
Sbjct: 1    MPEPTKKEENEVPAPAPPPEEPSKEKEAGTTPAKDEEEVSPPSALPPGLGSRALERKDSD 60

Query: 61   WTLVETPPGEEQAKQNANSQLSILFIEKPQGGTVKVGEDITFIAKVKAEDLLRKPTIKWF 120
            WTLVETPPGEEQAKQNANSQLSILFIEKPQGGTVKVGEDITFIAKVKAEDLLRKPTIKWF
Sbjct: 61   WTLVETPPGEEQAKQNANSQLSILFIEKPQGGTVKVGEDITFIAKVKAEDLLRKPTIKWF 120

Query: 121  KGKWMDLASKAGKHLQLKETFERHSRVYTFEMQIIKAKDNFAGNYRCEVTYKDKFDSCSF 180
            KGKWMDLASKAGKHLQLKETFERHSRVYTFEMQIIKAKDNFAGNYRCEVTYKDKFDSCSF
Sbjct: 121  KGKWMDLASKAGKHLQLKETFERHSRVYTFEMQIIKAKDNFAGNYRCEVTYKDKFDSCSF 180

Query: 181  DLEVHESTGTTPNIDIRSAFKRSGEGQEDAGELDFSGLLKRREVKQQEEEPQVDVWELLK 240
            DLEVHESTGTTPNIDIRSAFKRSGEGQEDAGELDFSGLLKRREVKQQEEEPQVDVWELLK
Sbjct: 181  DLEVHESTGTTPNIDIRSAFKRSGEGQEDAGELDFSGLLKRREVKQQEEEPQVDVWELLK 240

Query: 241  NAKPSEYEKIAFQYGITDLRGMLKRLKRMRREEKKSAAFAKILDPAYQVDKGGRVRFVVE 300
            NAKPSEYEKIAFQYGITDLRGMLKRLKRMRREEKKSAAFAKILDPAYQVDKGGRVRFVVE
Sbjct: 241  NAKPSEYEKIAFQYGITDLRGMLKRLKRMRREEKKSAAFAKILDPAYQVDKGGRVRFVVE 300

Query: 301  LADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTEL 360
            LADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTEL
Sbjct: 301  LADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTEL 360

Query: 361  FVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEG 420
            FVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEG
Sbjct: 361  FVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEG 420

Query: 421  KKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCE 480
            KKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCE
Sbjct: 421  KKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCE 480

Query: 481  ISENIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAK 540
            ISENIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAK
Sbjct: 481  ISENIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAK 540

Query: 541  VHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRT 600
            VHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRT
Sbjct: 541  VHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRT 600

Query: 601  ESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDW 660
            ESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDW
Sbjct: 601  ESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDW 660

Query: 661  CIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIF 720
            CIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIF
Sbjct: 661  CIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIF 720

Query: 721  AVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLE 780
            AVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLE
Sbjct: 721  AVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLE 780

Query: 781  YCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEI 840
            YCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEI
Sbjct: 781  YCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEI 840

Query: 841  IEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETD 900
            IEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETD
Sbjct: 841  IEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETD 900

Query: 901  TIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWT 960
            TIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWT
Sbjct: 901  TIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWT 960

Query: 961  PPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGL 1020
            PPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGL
Sbjct: 961  PPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGL 1020

Query: 1021 SEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGN 1080
            SEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGN
Sbjct: 1021 SEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGN 1080

Query: 1081 PKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECK 1140
            PKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECK
Sbjct: 1081 PKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECK 1140

Query: 1141 LEVKVIAQ 1148
            LEVKVI Q
Sbjct: 1141 LEVKVIYQ 1148


>gi|46049110 myosin binding protein C, slow type isoform 4 [Homo
            sapiens]
          Length = 1123

 Score = 2270 bits (5883), Expect = 0.0
 Identities = 1123/1148 (97%), Positives = 1123/1148 (97%), Gaps = 25/1148 (2%)

Query: 1    MPEPTKKEENEVPAPAPPPEEPSKEKEAGTTPAKDEEEVSPPSALPPGLGSRALERKDSD 60
            MPEPTKKEENEVPAPAPPPEEPSKEKEAGTTPAK                         D
Sbjct: 1    MPEPTKKEENEVPAPAPPPEEPSKEKEAGTTPAK-------------------------D 35

Query: 61   WTLVETPPGEEQAKQNANSQLSILFIEKPQGGTVKVGEDITFIAKVKAEDLLRKPTIKWF 120
            WTLVETPPGEEQAKQNANSQLSILFIEKPQGGTVKVGEDITFIAKVKAEDLLRKPTIKWF
Sbjct: 36   WTLVETPPGEEQAKQNANSQLSILFIEKPQGGTVKVGEDITFIAKVKAEDLLRKPTIKWF 95

Query: 121  KGKWMDLASKAGKHLQLKETFERHSRVYTFEMQIIKAKDNFAGNYRCEVTYKDKFDSCSF 180
            KGKWMDLASKAGKHLQLKETFERHSRVYTFEMQIIKAKDNFAGNYRCEVTYKDKFDSCSF
Sbjct: 96   KGKWMDLASKAGKHLQLKETFERHSRVYTFEMQIIKAKDNFAGNYRCEVTYKDKFDSCSF 155

Query: 181  DLEVHESTGTTPNIDIRSAFKRSGEGQEDAGELDFSGLLKRREVKQQEEEPQVDVWELLK 240
            DLEVHESTGTTPNIDIRSAFKRSGEGQEDAGELDFSGLLKRREVKQQEEEPQVDVWELLK
Sbjct: 156  DLEVHESTGTTPNIDIRSAFKRSGEGQEDAGELDFSGLLKRREVKQQEEEPQVDVWELLK 215

Query: 241  NAKPSEYEKIAFQYGITDLRGMLKRLKRMRREEKKSAAFAKILDPAYQVDKGGRVRFVVE 300
            NAKPSEYEKIAFQYGITDLRGMLKRLKRMRREEKKSAAFAKILDPAYQVDKGGRVRFVVE
Sbjct: 216  NAKPSEYEKIAFQYGITDLRGMLKRLKRMRREEKKSAAFAKILDPAYQVDKGGRVRFVVE 275

Query: 301  LADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTEL 360
            LADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTEL
Sbjct: 276  LADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTEL 335

Query: 361  FVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEG 420
            FVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEG
Sbjct: 336  FVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEG 395

Query: 421  KKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCE 480
            KKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCE
Sbjct: 396  KKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCE 455

Query: 481  ISENIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAK 540
            ISENIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAK
Sbjct: 456  ISENIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAK 515

Query: 541  VHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRT 600
            VHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRT
Sbjct: 516  VHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRT 575

Query: 601  ESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDW 660
            ESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDW
Sbjct: 576  ESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDW 635

Query: 661  CIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIF 720
            CIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIF
Sbjct: 636  CIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIF 695

Query: 721  AVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLE 780
            AVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLE
Sbjct: 696  AVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLE 755

Query: 781  YCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEI 840
            YCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEI
Sbjct: 756  YCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEI 815

Query: 841  IEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETD 900
            IEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETD
Sbjct: 816  IEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETD 875

Query: 901  TIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWT 960
            TIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWT
Sbjct: 876  TIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWT 935

Query: 961  PPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGL 1020
            PPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGL
Sbjct: 936  PPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGL 995

Query: 1021 SEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGN 1080
            SEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGN
Sbjct: 996  SEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGN 1055

Query: 1081 PKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECK 1140
            PKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECK
Sbjct: 1056 PKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECK 1115

Query: 1141 LEVKVIAQ 1148
            LEVKVIAQ
Sbjct: 1116 LEVKVIAQ 1123


>gi|46049119 myosin binding protein C, slow type isoform 3 [Homo
            sapiens]
          Length = 1141

 Score = 2258 bits (5850), Expect = 0.0
 Identities = 1122/1166 (96%), Positives = 1123/1166 (96%), Gaps = 43/1166 (3%)

Query: 1    MPEPTKKEENEVPAPAPPPEEPSKEKEAGTTPAKDEEEVSPPSALPPGLGSRALERKDSD 60
            MPEPTKKEENEVPAPAPPPEEPSKEKEAGTTPAK                         D
Sbjct: 1    MPEPTKKEENEVPAPAPPPEEPSKEKEAGTTPAK-------------------------D 35

Query: 61   WTLVETPPGEEQAKQNANSQLSILFIEKPQGGTVKVGEDITFIAKVKAEDLLRKPTIKWF 120
            WTLVETPPGEEQAKQNANSQLSILFIEKPQGGTVKVGEDITFIAKVKAEDLLRKPTIKWF
Sbjct: 36   WTLVETPPGEEQAKQNANSQLSILFIEKPQGGTVKVGEDITFIAKVKAEDLLRKPTIKWF 95

Query: 121  KGKWMDLASKAGKHLQLKETFERHSRVYTFEMQIIKAKDNFAGNYRCEVTYKDKFDSCSF 180
            KGKWMDLASKAGKHLQLKETFERHSRVYTFEMQIIKAKDNFAGNYRCEVTYKDKFDSCSF
Sbjct: 96   KGKWMDLASKAGKHLQLKETFERHSRVYTFEMQIIKAKDNFAGNYRCEVTYKDKFDSCSF 155

Query: 181  DLEVHESTGTTPNIDIRSAFKRSGEGQEDAGELDFSGLLKRREVKQQEEEPQVDVWELLK 240
            DLEVHESTGTTPNIDIRSAFKRSGEGQEDAGELDFSGLLKRREVKQQEEEPQVDVWELLK
Sbjct: 156  DLEVHESTGTTPNIDIRSAFKRSGEGQEDAGELDFSGLLKRREVKQQEEEPQVDVWELLK 215

Query: 241  NAKPSEYEKIAFQYGITDLRGMLKRLKRMRREEKKSAAFAKILDPAYQVDKGGRVRFVVE 300
            NAKPSEYEKIAFQYGITDLRGMLKRLKRMRREEKKSAAFAKILDPAYQVDKGGRVRFVVE
Sbjct: 216  NAKPSEYEKIAFQYGITDLRGMLKRLKRMRREEKKSAAFAKILDPAYQVDKGGRVRFVVE 275

Query: 301  LADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTEL 360
            LADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTEL
Sbjct: 276  LADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTEL 335

Query: 361  FVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEG 420
            FVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEG
Sbjct: 336  FVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEG 395

Query: 421  KKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCE 480
            KKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCE
Sbjct: 396  KKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCE 455

Query: 481  ISENIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAK 540
            ISENIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAK
Sbjct: 456  ISENIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAK 515

Query: 541  VHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRT 600
            VHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRT
Sbjct: 516  VHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRT 575

Query: 601  ESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDW 660
            ESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDW
Sbjct: 576  ESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDW 635

Query: 661  CIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIF 720
            CIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIF
Sbjct: 636  CIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIF 695

Query: 721  AVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLE 780
            AVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLE
Sbjct: 696  AVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLE 755

Query: 781  YCFEGT------------------EDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNA 822
            YCFEG+                  EDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNA
Sbjct: 756  YCFEGSTSAKQSDENGEAAYDLPAEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNA 815

Query: 823  AGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKK 882
            AGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKK
Sbjct: 816  AGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKK 875

Query: 883  DGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPP 942
            DGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPP
Sbjct: 876  DGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPP 935

Query: 943  QIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITEL 1002
            QIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITEL
Sbjct: 936  QIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITEL 995

Query: 1003 VIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVN 1062
            VIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVN
Sbjct: 996  VIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVN 1055

Query: 1063 TYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGG 1122
            TYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGG
Sbjct: 1056 TYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGG 1115

Query: 1123 TYCCKAVNDLGTVEIECKLEVKVIAQ 1148
            TYCCKAVNDLGTVEIECKLEVKVIAQ
Sbjct: 1116 TYCCKAVNDLGTVEIECKLEVKVIAQ 1141


>gi|133908641 myosin binding protein C, fast type [Homo sapiens]
          Length = 1141

 Score = 1164 bits (3010), Expect = 0.0
 Identities = 569/1155 (49%), Positives = 780/1155 (67%), Gaps = 43/1155 (3%)

Query: 17   PPPEEPSKEKEAGTTPAKDEEEVSPPSALPPGLGSRALERKDSDWTLVETPPGEEQAKQN 76
            P  +  +K+   G    K   + +PP   P      A     S     E P G       
Sbjct: 2    PEAKPAAKKAPKGKDAPKGAPKEAPPKEAPAEAPKEAPPEDQSP--TAEEPTG------- 52

Query: 77   ANSQLSILFIEKPQGGTVKVGEDITFIAKVKAEDLLRKPTIKWFKGKWMDLASKAGKHLQ 136
                   +F++KP   +V+ G+D   +AKV  ++L  KPTIKWFKGKW++L SK+G    
Sbjct: 53   -------VFLKKPDSVSVETGKDAVVVAKVNGKELPDKPTIKWFKGKWLELGSKSGARFS 105

Query: 137  LKETFERHSRVYTFEMQIIKAKDNFAGNYRCEVTYKDKFDSCSFDLEVHESTGTTPNIDI 196
             KE+    S VYT E+ I K      G YR EV  KD  DSC F+++V           +
Sbjct: 106  FKESHNSASNVYTVELHIGKVVLGDRGYYRLEVKAKDTCDSCGFNIDVEAPRQDASGQSL 165

Query: 197  RSAFKRSGEGQED-AGELDFSGLLKRREVKQQEEEPQV----------DVWELLKNAKPS 245
             S FKR+ E + D AGELDFSGLLK+REV ++E++ +           ++WELLK AK S
Sbjct: 166  ES-FKRTSEKKSDTAGELDFSGLLKKREVVEEEKKKKKKDDDDLGIPPEIWELLKGAKKS 224

Query: 246  EYEKIAFQYGITDLRGMLKRLKRMRREEKKSAAFAKILDPAYQVDKGGRVRFVVELADPK 305
            EYEKIAFQYGITDLRGMLKRLK+ + E KKSAAF K LDPAYQVD+G +++ +VE++DP 
Sbjct: 225  EYEKIAFQYGITDLRGMLKRLKKAKVEVKKSAAFTKKLDPAYQVDRGNKIKLMVEISDPD 284

Query: 306  LEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTELFVREP 365
            L +KW+KNGQEI+PS+KY+FE+ G +RIL IN C + DD+ Y V   DEKC TELFV+EP
Sbjct: 285  LTLKWFKNGQEIKPSSKYVFENVGKKRILTINKCTLADDAAYEVAVKDEKCFTELFVKEP 344

Query: 366  PIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGP--KSRYRIRVEGKKH 423
            P+++   LED   + G+RVE+  EVSE+ A V W K+G E+      K+RYR + +GK+H
Sbjct: 345  PVLIVTPLEDQQVFVGDRVEMAVEVSEEGAQVMWMKDGVELTREDSFKARYRFKKDGKRH 404

Query: 424  ILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCEIS- 482
            ILI     + D   Y V+T GGQ  A+L V+ K L++L  + D TV   ++   KCE+S 
Sbjct: 405  ILIFSDVVQEDRGRYQVITNGGQCEAELIVEEKQLEVLQDIADLTVKASEQAVFKCEVSD 464

Query: 483  ENIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAKVH 542
            E + GKW KNG+ V+ S R+ + H GR HKLVI +   EDEGDY F PD Y ++L AK++
Sbjct: 465  EKVTGKWYKNGVEVRPSKRITISHVGRFHKLVIDDVRPEDEGDYTFVPDGYALSLSAKLN 524

Query: 543  VID----------PPKIILD--GLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKA 590
             ++          PPKI LD  G  ++N + V+AGNKLRL++ I+GEPPP A W +GD+ 
Sbjct: 525  FLEIKVEYVPKQEPPKIHLDCSGKTSENAIVVVAGNKLRLDVSITGEPPPVATWLKGDEV 584

Query: 591  IMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVA 650
                 GR R E   D S+ VI+ A+R+D G Y I + N  GE  ASI ++VVD PDPP A
Sbjct: 585  FTTTEGRTRIEKRVDCSSFVIESAQREDEGRYTIKVTNPVGEDVASIFLQVVDVPDPPEA 644

Query: 651  PTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMI 710
              +T VG+DW I+ WEPP YDGG P+ GY +ERKKK S RWM+LNF++  ETT+E  KMI
Sbjct: 645  VRITSVGEDWAILVWEPPMYDGGKPVTGYLVERKKKGSQRWMKLNFEVFTETTYESTKMI 704

Query: 711  EGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIG 770
            EG+ YE+R+FAVNAIG+S+PSM ++PF+P+A TS P  L V+ VTDTT T++WRPP+ IG
Sbjct: 705  EGILYEMRVFAVNAIGVSQPSMNTKPFMPIAPTSEPLHLIVEDVTDTTTTLKWRPPNRIG 764

Query: 771  AAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKY 830
            A G+DGY++EYC EG+E+W+ AN + +++  FT+  LPT A+I  RV  VN AG SEP  
Sbjct: 765  AGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPAT 824

Query: 831  YSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKN 890
             +QP+ ++EI EPPKIR+PRHL+QTYIR+VGE +NLV+PFQGKPRP++ W K GA +D +
Sbjct: 825  LAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPLDTS 884

Query: 891  QINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDV 950
            ++++R S+ DT+ F+R+A RS SG+Y+L V+++   +TA+I I+++++ GPP  V +++V
Sbjct: 885  RVHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGPPINVMVKEV 944

Query: 951  WGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYF 1010
            WG N  + W  PKDDGN+ I GY +QKADKK+MEWF V E    TS T+++L++GNEYYF
Sbjct: 945  WGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYF 1004

Query: 1011 RVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYN 1070
            RV++EN+CGLS+   ++K +A I + G  +K   Y++ DF  AP F  PL++   +AGY+
Sbjct: 1005 RVYTENICGLSDSPGVSKNTARILKTGITFKPFEYKEHDFRMAPKFLTPLIDRVVVAGYS 1064

Query: 1071 ATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVN 1130
            A LNC+VRG+PKPK+ WMKNK+ I +DP++ + + QGV TL IR+PSP+D GTY C+AVN
Sbjct: 1065 AALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVN 1124

Query: 1131 DLGTVEIECKLEVKV 1145
            +LG    ECKLEV+V
Sbjct: 1125 ELGEALAECKLEVRV 1139


>gi|148596957 myosin binding protein C, cardiac [Homo sapiens]
          Length = 1274

 Score = 1147 bits (2966), Expect = 0.0
 Identities = 582/1189 (48%), Positives = 775/1189 (65%), Gaps = 78/1189 (6%)

Query: 14   APAPPPEEPSKEKEAGTTPAKDEEEVSPPSALPPGLGSRALERKDSDWTLVETPPGEEQA 73
            APAP P E +        PA +  E +P    P G  S AL          + P G    
Sbjct: 105  APAPAPAEATGAPGEAPAPAAELGESAPS---PKGSSSAALNGPTPG--APDDPIG---- 155

Query: 74   KQNANSQLSILFIEKPQGGTVKVGEDITFIAKVKAEDLLRKPTIKWFKGKWMDLASKAGK 133
                      LF+ +PQ G V VG  ITF A+V    LL+ P +KWFKGKW+DL+SK G+
Sbjct: 156  ----------LFVMRPQDGEVTVGGSITFSARVAGASLLKPPVVKWFKGKWVDLSSKVGQ 205

Query: 134  HLQLKETFERHSRVYTFEMQIIKAKDNFAGNYRCEVTYKDKFDSCSFDLEVHESTGTTPN 193
            HLQL ++++R S+VY FE+ I  A+  F G+YRCEV+ KDKFD  +F+L VHE+ GT  +
Sbjct: 206  HLQLHDSYDRASKVYLFELHITDAQPAFTGSYRCEVSTKDKFDCSNFNLTVHEAMGTG-D 264

Query: 194  IDIRSAFKRSG---------EGQEDAGELDFSGLLKRREV------KQQEEEPQVDVWEL 238
            +D+ SAF+R+          +  ED G LDFS LLK+R+        + E   + DVWE+
Sbjct: 265  LDLLSAFRRTSLAGGGRRISDSHEDTGILDFSSLLKKRDSFRTPRDSKLEAPAEEDVWEI 324

Query: 239  LKNAKPSEYEKIAFQYGITDLRGMLKRLKRMRREEKKSAAFAKILDPAYQVDKGGRVRFV 298
            L+ A PSEYE+IAFQYG+TDLRGMLKRLK MRR+EKKS AF K L+PAYQV KG ++R  
Sbjct: 325  LRQAPPSEYERIAFQYGVTDLRGMLKRLKGMRRDEKKSTAFQKKLEPAYQVSKGHKIRLT 384

Query: 299  VELADPKLEVKWYKNGQEIRPS-TKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCS 357
            VELAD   EVKW KNGQEI+ S +KYIFE  G +R L I+ C + DD+ Y    G EKCS
Sbjct: 385  VELADHDAEVKWLKNGQEIQMSGSKYIFESIGAKRTLTISQCSLADDAAYQCVVGGEKCS 444

Query: 358  TELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIR 417
            TELFV+EPP+++T+ LED     G+RVE ECEVSE+ A VKW K+G E+      +YR +
Sbjct: 445  TELFVKEPPVLITRPLEDQLVMVGQRVEFECEVSEEGAQVKWLKDGVELTREETFKYRFK 504

Query: 418  VEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICL 477
             +G++H LII  A   DA  Y++ T+GGQ+ A+L V  K L++   + D  V    +   
Sbjct: 505  KDGQRHHLIINEAMLEDAGHYALCTSGGQALAELIVQEKKLEVYQSIADLMVGAKDQAVF 564

Query: 478  KCEIS-ENIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVT 536
            KCE+S EN+ G W KNG  +    R+KV H GR+HKL I +    DE DY F P+ +   
Sbjct: 565  KCEVSDENVRGVWLKNGKELVPDSRIKVSHIGRVHKLTIDDVTPADEADYSFVPEGFACN 624

Query: 537  LPAKVHVID----------PPKIILD--GLDADNTVTVIAGNKLRLEIPISGEPPPKAMW 584
            L AK+H ++          PPKI LD  G   D T+ V+AGNKLRL++PISG+P P  +W
Sbjct: 625  LSAKLHFMEVKIDFVPRQEPPKIHLDCPGRIPD-TIVVVAGNKLRLDVPISGDPAPTVIW 683

Query: 585  SR--------------------GD--------KAIMEGSGRIRTESYPDSSTLVIDIAER 616
             +                    GD        K + E  GR+R E+  D S   ++ AE+
Sbjct: 684  QKAITQGNKAPARPAPDAPEDTGDSDEWVFDKKLLCETEGRVRVETTKDRSIFTVEGAEK 743

Query: 617  DDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPI 676
            +D GVY + +KN  GE   ++ VKV+D PD P AP ++ VG+D C + WEPPAYDGG PI
Sbjct: 744  EDEGVYTVTVKNPVGEDQVNLTVKVIDVPDAPAAPKISNVGEDSCTVQWEPPAYDGGQPI 803

Query: 677  LGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRP 736
            LGY +ERKKK+S RWMRLNFDL +E + E ++MIEGV YE+R++AVNAIG+S+PS  S+P
Sbjct: 804  LGYILERKKKKSYRWMRLNFDLIQELSHEARRMIEGVVYEMRVYAVNAIGMSRPSPASQP 863

Query: 737  FVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDL 796
            F+P+   S PT L V+ V+DTTV+++WRPP+ +GA GLDGY +EYC EG  +W+ A + L
Sbjct: 864  FMPIGPPSEPTHLAVEDVSDTTVSLKWRPPERVGAGGLDGYSVEYCPEGCSEWVAALQGL 923

Query: 797  IDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTY 856
             + T   +  LPT A++  RV+A N AG   P   ++P+ V+EI++ P++++PRHL+QT 
Sbjct: 924  TEHTSILVKDLPTGARLLFRVRAHNMAGPGAPVTTTEPVTVQEILQRPRLQLPRHLRQTI 983

Query: 857  IRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKY 916
             ++VGE VNL+IPFQGKPRP++TW K+G  +   +++IRNS TDTI+FIR A R HSG Y
Sbjct: 984  QKKVGEPVNLLIPFQGKPRPQVTWTKEGQPLAGEEVSIRNSPTDTILFIRAARRVHSGTY 1043

Query: 917  DLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQ 976
             + V+++   + A++ +Q++D+P PPQ +++ D WG NVAL W PP+D GN  + GYT+Q
Sbjct: 1044 QVTVRIENMEDKATLVLQVVDKPSPPQDLRVTDAWGLNVALEWKPPQDVGNTELWGYTVQ 1103

Query: 977  KADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARD 1036
            KADKK+MEWFTV+EHY RT   + EL+IGN YYFRVFS+NM G S+ A  TKE   I R 
Sbjct: 1104 KADKKTMEWFTVLEHYRRTHCVVPELIIGNGYYFRVFSQNMVGFSDRAATTKEPVFIPRP 1163

Query: 1037 GKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVD 1096
            G  Y+ P Y+  DFSEAP FTQPLVN   IAGY A L C+VRG+PKPKI+W KN + + +
Sbjct: 1164 GITYEPPNYKALDFSEAPSFTQPLVNRSVIAGYTAMLCCAVRGSPKPKISWFKNGLDLGE 1223

Query: 1097 DPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVKV 1145
            D R+RMFS QGV TLEIRKP P+DGG Y C+A N  G    EC+LEV+V
Sbjct: 1224 DARFRMFSKQGVLTLEIRKPCPFDGGIYVCRATNLQGEARCECRLEVRV 1272



 Score = 39.3 bits (90), Expect = 0.022
 Identities = 33/131 (25%), Positives = 51/131 (38%), Gaps = 6/131 (4%)

Query: 273 EKKSAAFAKILDPAYQVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQR 332
           +K  +AF+K    + +V  G    F  E     ++V+W + G +I  S KY    +G + 
Sbjct: 6   KKPVSAFSK-KPRSVEVAAGSPAVFEAETERAGVKVRWQRGGSDISASNKYGLATEGTRH 64

Query: 333 ILFINNCQMTDDSEYYVTAGDEKCSTELFV-----REPPIMVTKQLEDTTAYCGERVELE 387
            L +      D   Y V AG  K   +L V      EP +       + T   GE     
Sbjct: 65  TLTVREVGPADQGSYAVIAGSSKVKFDLKVIEAEKAEPMLAPAPAPAEATGAPGEAPAPA 124

Query: 388 CEVSEDDANVK 398
            E+ E   + K
Sbjct: 125 AELGESAPSPK 135



 Score = 39.3 bits (90), Expect = 0.022
 Identities = 23/97 (23%), Positives = 41/97 (42%), Gaps = 6/97 (6%)

Query: 363 REPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKK 422
           ++P    +K+        G     E E       V+W + G +I     ++Y +  EG +
Sbjct: 6   KKPVSAFSKKPRSVEVAAGSPAVFEAETERAGVKVRWQRGGSDI--SASNKYGLATEGTR 63

Query: 423 HILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLK 459
           H L +     AD   Y+V+      S+K+  DLK ++
Sbjct: 64  HTLTVREVGPADQGSYAVIA----GSSKVKFDLKVIE 96


>gi|55956914 myosin binding protein H [Homo sapiens]
          Length = 477

 Score =  458 bits (1178), Expect = e-128
 Identities = 221/427 (51%), Positives = 293/427 (68%), Gaps = 5/427 (1%)

Query: 721  AVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLE 780
            A  A   +KP+ PS       V S P LLT+D V+ ++VT+ W PP+ +G  GL GYVLE
Sbjct: 54   APTASTATKPAPPSED-----VPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLE 108

Query: 781  YCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEI 840
             C EG  +W+  +   +  T+ T+  L    K  +RV AV++AGA  P    QPI ++E 
Sbjct: 109  LCREGASEWVPVSARPMMVTQQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQPIHIREN 168

Query: 841  IEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETD 900
            IE PKIR+PRHL+QTYIR+VGE VNL IPFQGKP+P+ TW  +G  +D  ++++R  + D
Sbjct: 169  IEAPKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHALDSQRVSMRTGDQD 228

Query: 901  TIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWT 960
            +I+FIR A+RS SG+Y+L V+V+     A IDI +I++PGPP  +++ DVWG N AL WT
Sbjct: 229  SILFIRSAQRSDSGRYELTVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWT 288

Query: 961  PPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGL 1020
            PP+D GN  + GY +QKADKK+ +WFTV+E YH T+ TI++L+IGN Y FRVFSEN+CGL
Sbjct: 289  PPQDTGNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFRVFSENLCGL 348

Query: 1021 SEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGN 1080
            S  AT+TKE A I +     K   + + DFSEAP FTQPL +  +  GY+  L CSVR +
Sbjct: 349  STSATVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYSTQLFCSVRAS 408

Query: 1081 PKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECK 1140
            PKPKI WMKNK+ I  +P+YR  S QGVCTLEIRKPSP+D G Y CKA+N LG   ++C+
Sbjct: 409  PKPKIIWMKNKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAINVLGEASVDCR 468

Query: 1141 LEVKVIA 1147
            LEVK  A
Sbjct: 469  LEVKASA 475



 Score = 89.7 bits (221), Expect = 1e-17
 Identities = 50/164 (30%), Positives = 84/164 (51%), Gaps = 3/164 (1%)

Query: 565 GNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHI 624
           G  + L+IP  G+P P+A W+    A+   S R+   +    S L I  A+R DSG Y +
Sbjct: 189 GETVNLQIPFQGKPKPQATWTHNGHAL--DSQRVSMRTGDQDSILFIRSAQRSDSGRYEL 246

Query: 625 NLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERK 684
            ++ E  EA A I + V++ P PP +  + +V      + W PP   G + +LGY +++ 
Sbjct: 247 TVRVEDLEAKAVIDILVIEKPGPPSSIRLLDVWGCNAALQWTPPQDTGNTELLGYMVQKA 306

Query: 685 KKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGIS 728
            K++ +W  +  +    TT     +I G +Y  R+F+ N  G+S
Sbjct: 307 DKKTGQWFTV-LERYHPTTCTISDLIIGNSYSFRVFSENLCGLS 349



 Score = 45.1 bits (105), Expect = 4e-04
 Identities = 24/94 (25%), Positives = 46/94 (48%)

Query: 643 DFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKET 702
           D P  P+  T+ +V      ++WEPP   G   + GY +E  ++ +S W+ ++      T
Sbjct: 69  DVPSAPLLLTLDDVSSSSVTVSWEPPERLGRLGLQGYVLELCREGASEWVPVSARPMMVT 128

Query: 703 TFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRP 736
               + +  G  + +R+ AV++ G   P+M  +P
Sbjct: 129 QQTVRNLALGDKFLLRVSAVSSAGAGPPAMLDQP 162



 Score = 38.9 bits (89), Expect = 0.028
 Identities = 73/314 (23%), Positives = 118/314 (37%), Gaps = 45/314 (14%)

Query: 362 VREPPIMVTKQLEDT-TAYCGERVELECEVS-EDDANVKWFKNGEEIIPGPKSRYRIRVE 419
           +  P I V + L  T     GE V L+     +      W  NG  +      R  +R  
Sbjct: 169 IEAPKIRVPRHLRQTYIRQVGETVNLQIPFQGKPKPQATWTHNGHAL---DSQRVSMRTG 225

Query: 420 GKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNL----GKEI 475
            +  IL I  A ++D+  Y +        AK  +D+  L I  P    ++ L    G   
Sbjct: 226 DQDSILFIRSAQRSDSGRYELTVRVEDLEAKAVIDI--LVIEKPGPPSSIRLLDVWGCNA 283

Query: 476 CLKCEISENIPGKWTKNGLPVQESDR--------LKVVHKGR--IHKLVIANALTEDEGD 525
            L+    ++  G     G  VQ++D+        L+  H     I  L+I N+ +     
Sbjct: 284 ALQWTPPQDT-GNTELLGYMVQKADKKTGQWFTVLERYHPTTCTISDLIIGNSYSFR--- 339

Query: 526 YVFAPDAYNVTLPA----------KVHVIDPPK--IILDGLDADNTVTVIA------GNK 567
            VF+ +   ++  A          K  +   PK  I  D  +A +    +A      G  
Sbjct: 340 -VFSENLCGLSTSATVTKELAHIQKADIAAKPKGFIERDFSEAPSFTQPLADHTSTPGYS 398

Query: 568 LRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLK 627
            +L   +   P PK +W + +K  ++G+ + R  S     TL I      DSGVY     
Sbjct: 399 TQLFCSVRASPKPKIIWMK-NKMEIQGNPKYRALSEQGVCTLEIRKPSPFDSGVYTCKAI 457

Query: 628 NEAGEAHASIKVKV 641
           N  GEA    +++V
Sbjct: 458 NVLGEASVDCRLEV 471


>gi|194018539 myosin binding protein H-like [Homo sapiens]
          Length = 354

 Score =  375 bits (963), Expect = e-103
 Identities = 172/322 (53%), Positives = 232/322 (72%), Gaps = 4/322 (1%)

Query: 824  GASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKD 883
            GA  P     P L+  I E PKI +PR L+QTYIR+VG+ VNL+IPFQGKP+P+  W  D
Sbjct: 35   GAGSPT----PQLLPPIEEHPKIWLPRALRQTYIRKVGDTVNLLIPFQGKPKPQAIWTHD 90

Query: 884  GAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQ 943
            G  +D  ++++RN E D+I+FIR+A+R+ SG+Y L+V++     TA+IDI +I+RPGPPQ
Sbjct: 91   GCALDTRRVSVRNGEQDSILFIREAQRADSGRYQLRVQLGGLEATATIDILVIERPGPPQ 150

Query: 944  IVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELV 1003
             +K+ DVWG +  L WTPP+D GN A+ GYT+QKAD KS  WFTV+EHYHRTS  +++L+
Sbjct: 151  SIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSDLI 210

Query: 1004 IGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNT 1063
            IGN Y FRVF+EN CGLSE A +T + A I +   +YK   +   DFSEAP FTQPL + 
Sbjct: 211  IGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEAPKFTQPLADC 270

Query: 1064 YAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGT 1123
              + GYN  L C VR +P+PKI W+KNK+ I  +P+YR  ++ G+C+LEIRKP P+DGG 
Sbjct: 271  TTVTGYNTQLFCCVRASPRPKIIWLKNKMDIQGNPKYRALTHLGICSLEIRKPGPFDGGI 330

Query: 1124 YCCKAVNDLGTVEIECKLEVKV 1145
            Y CKAVN LG   ++C+++VKV
Sbjct: 331  YTCKAVNPLGEASVDCRVDVKV 352



 Score = 81.3 bits (199), Expect = 5e-15
 Identities = 48/165 (29%), Positives = 84/165 (50%), Gaps = 3/165 (1%)

Query: 565 GNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHI 624
           G+ + L IP  G+P P+A+W+    A+   + R+   +    S L I  A+R DSG Y +
Sbjct: 68  GDTVNLLIPFQGKPKPQAIWTHDGCAL--DTRRVSVRNGEQDSILFIREAQRADSGRYQL 125

Query: 625 NLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERK 684
            ++    EA A+I + V++ P PP +  + +V      + W PP   G + +LGY +++ 
Sbjct: 126 RVQLGGLEATATIDILVIERPGPPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKA 185

Query: 685 KKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISK 729
             +S  W  +  +    T+     +I G +Y  R+FA N  G+S+
Sbjct: 186 DTKSGLWFTV-LEHYHRTSCIVSDLIIGNSYAFRVFAENQCGLSE 229



 Score = 37.0 bits (84), Expect = 0.11
 Identities = 36/161 (22%), Positives = 56/161 (34%), Gaps = 19/161 (11%)

Query: 745 PPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTI 804
           PP  + +  V   + T+ W PP   G   L GY ++     +  W     +   +T   +
Sbjct: 148 PPQSIKLVDVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTV-LEHYHRTSCIV 206

Query: 805 TGLPTDAKIFVRVKAVNAAGASEPK---------------YYSQPILVKEIIEPPKIRIP 849
           + L        RV A N  G SE                 Y ++    ++  E PK   P
Sbjct: 207 SDLIIGNSYAFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEAPKFTQP 266

Query: 850 RHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKN 890
                T     G    L    +  PRP++ W K+  +I  N
Sbjct: 267 LADCTTV---TGYNTQLFCCVRASPRPKIIWLKNKMDIQGN 304



 Score = 34.7 bits (78), Expect = 0.53
 Identities = 57/260 (21%), Positives = 93/260 (35%), Gaps = 38/260 (14%)

Query: 413 RYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLG 472
           R  +R   +  IL I  A +AD+  Y +    G   A  ++D+  L I  P   Q++ L 
Sbjct: 98  RVSVRNGEQDSILFIREAQRADSGRYQLRVQLGGLEATATIDI--LVIERPGPPQSIKLV 155

Query: 473 KEICLKCEISENIP---GKWTKNGLPVQESDR--------LKVVHKGR--IHKLVIANA- 518
                   +    P   G     G  VQ++D         L+  H+    +  L+I N+ 
Sbjct: 156 DVWGFSATLEWTPPQDTGNTALLGYTVQKADTKSGLWFTVLEHYHRTSCIVSDLIIGNSY 215

Query: 519 -----------------LTEDEGDYVFAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVT 561
                            +T D      A   Y     A+    + PK      D     T
Sbjct: 216 AFRVFAENQCGLSETAPITTDLAHIQKAATVYKTKGFAQRDFSEAPKFTQPLADC----T 271

Query: 562 VIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGV 621
            + G   +L   +   P PK +W + +K  ++G+ + R  ++    +L I      D G+
Sbjct: 272 TVTGYNTQLFCCVRASPRPKIIWLK-NKMDIQGNPKYRALTHLGICSLEIRKPGPFDGGI 330

Query: 622 YHINLKNEAGEAHASIKVKV 641
           Y     N  GEA    +V V
Sbjct: 331 YTCKAVNPLGEASVDCRVDV 350


>gi|253970427 immunoglobulin superfamily, member 22 [Homo sapiens]
          Length = 1326

 Score =  303 bits (777), Expect = 5e-82
 Identities = 246/888 (27%), Positives = 381/888 (42%), Gaps = 46/888 (5%)

Query: 288  QVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEY 347
            +V +  R     EL    + ++W K+GQ +   TKY   H+G +  L I + Q++D  EY
Sbjct: 429  RVKERSRACLECELTSKDVTLRWKKDGQLLMHGTKYSMNHEGKRAELIIEDAQLSDGGEY 488

Query: 348  YVTAGDEKCSTELF------VREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFK 401
             V A  +   TE +      V E    V   + D  A  G   EL   ++++     W K
Sbjct: 489  TVVAMQDGDPTEYYSTAIVTVEERLATVKSGMSDVHAATGSPAELCVVLNDEKVEGVWLK 548

Query: 402  NGEEI--IPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPL- 458
            +G+EI  +PG     +I  +G  H LI          +Y+    G +S A + +   P  
Sbjct: 549  DGKEITDLPG----MQIVKQGAVHKLIFPSMGPEHEGKYTFRAKGTESEASVFIADPPTI 604

Query: 459  --KILTPLTDQ--TVNLGKEICLKCEISENIPGK--WTKNGLPVQESDRLKVVHKGRIHK 512
               +L  L     TV +G    +K         K  W K+G+ V E +R+ +        
Sbjct: 605  DPSVLEALAAHAITVKVGHTAHIKVPFRGKPLPKVTWYKDGMEVTEEERVSMERGEDQAL 664

Query: 513  LVIANALTEDEGDYVFA--PDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRL 570
            L I+N + ED G  +     D  + T    + V+D PK     ++           K + 
Sbjct: 665  LTISNCVREDSGLILLKLKNDHGSATATLHLSVLDRPKPPQGRVEFLELSGSCVHMKWKA 724

Query: 571  EIPISGEPPPKAMWSR---GDKA---IMEGSGRIR---TESYPDSSTLVIDIAERDDSGV 621
                 G P  + +  R   G K+   I E  G++    T    +       I   +  GV
Sbjct: 725  PKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVTNFSTNKVEEGKAYQFRILAVNSEGV 784

Query: 622  YHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFI 681
                  ++  E         ++ P     P VT+V  +   + W  P  DGG+P+LGY +
Sbjct: 785  ------SDPLETEEVFAGNPIEPPGFASQPQVTDVTKEAVTITWNAPTQDGGAPVLGYIV 838

Query: 682  ERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLA 741
            ER+KK S+ W+ +N D  + T      ++E   YE R+ AVN  G  +PS+PS   V   
Sbjct: 839  ERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIAVNKAGPGQPSVPSSSVVAKD 898

Query: 742  VTSPPTL---LTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLID 798
               PP L   L V   +++++++ WR P         GY+LE   E T++W    K  I 
Sbjct: 899  PVKPPGLVQDLHVSDSSNSSISLAWREPAE--GDPPSGYILEMRAEDTKEWSKCTKIPIS 956

Query: 799  KTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIR 858
             T +T+ GL    K F R++AVN AG  EP    + +        PK  +   LK   + 
Sbjct: 957  GTCYTVGGLIERQKYFFRIRAVNEAGVGEPVELDKGVRAMPPPAAPKFDLSARLKSHMVV 1016

Query: 859  RVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDL 918
            R G A+ +   F G P P++ W+KDG    K +  I  S+  +   I   +RS SG Y +
Sbjct: 1017 RAGTALCIHAAFSGSPPPDVIWQKDGVP-TKGRETITKSKNHSQFLINSTKRSDSGVYRI 1075

Query: 919  QVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKA 978
             ++ +       I +++ D P PP  +++ +     V LTW    D        Y I K 
Sbjct: 1076 LLQNEFGEARYDIHVRVADFPRPPTNLRLFEEVPNTVTLTWNHSPDVQEDGEAHYIIMKR 1135

Query: 979  DKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARD-- 1036
            D  +  W+T  E       T+T L+ G +YYFRV + N  G SE    ++++ +I +D  
Sbjct: 1136 DASTATWYTAAERVFSNKYTVTGLLPGRKYYFRVVARNEIGDSEPLD-SRDTWLINKDQI 1194

Query: 1037 -GKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIV 1095
                 K   YE  D+  AP F  PL     + G + T+ C+  GNP+P +T  K  V I 
Sbjct: 1195 QDLSAKLKPYEKKDWRHAPRFVTPLKPHTVLRGQDCTMTCAFLGNPRPTVTLYKGDVNIT 1254

Query: 1096 DDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1143
             + ++   S  GVCTL I   +  D G Y     N+LG     C L V
Sbjct: 1255 ANSKFWYNSTSGVCTLVIPTCTLKDSGDYSVLVENELGKDRSSCTLTV 1302



 Score =  260 bits (664), Expect = 6e-69
 Identities = 173/576 (30%), Positives = 280/576 (48%), Gaps = 25/576 (4%)

Query: 297 FVVELADPKLEVKWYKNGQEIRPSTKY--IFEHKGCQRILFINNCQMTDDSEYYVTAGDE 354
           F + L+  +    W  NG+E++   KY       G    L I + +++D  E+   AG+ 
Sbjct: 347 FEIRLSKKEPNFVWKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSDSGEFSAEAGNL 406

Query: 355 KCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRY 414
               +L +   PI     L++       R  LECE++  D  ++W K+G+ ++ G K  Y
Sbjct: 407 VQKAQLTIDRIPIKFVSNLKNVRVKERSRACLECELTSKDVTLRWKKDGQLLMHGTK--Y 464

Query: 415 RIRVEGKKHILIIEGATKADAAEYSVMT------TGGQSSAKLSVDLKPLKILTPLTDQT 468
            +  EGK+  LIIE A  +D  EY+V+       T   S+A ++V+ +   + + ++D  
Sbjct: 465 SMNHEGKRAELIIEDAQLSDGGEYTVVAMQDGDPTEYYSTAIVTVEERLATVKSGMSDVH 524

Query: 469 VNLGK--EICLKCEISENIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDY 526
              G   E+C+     E + G W K+G  + +   +++V +G +HKL+  +   E EG Y
Sbjct: 525 AATGSPAELCVVLN-DEKVEGVWLKDGKEITDLPGMQIVKQGAVHKLIFPSMGPEHEGKY 583

Query: 527 VFAPDAYNVTLPAKVHVIDPPKI---ILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAM 583
            F   A      A V + DPP I   +L+ L A + +TV  G+   +++P  G+P PK  
Sbjct: 584 TFR--AKGTESEASVFIADPPTIDPSVLEALAA-HAITVKVGHTAHIKVPFRGKPLPKVT 640

Query: 584 WSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVD 643
           W +    + E   R+  E   D + L I    R+DSG+  + LKN+ G A A++ + V+D
Sbjct: 641 WYKDGMEVTEEE-RVSMERGEDQALLTISNCVREDSGLILLKLKNDHGSATATLHLSVLD 699

Query: 644 FPDPPVAPT-VTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKET 702
            P PP       E+      M W+ P  +GG P+  + +ER+      W+++     K T
Sbjct: 700 RPKPPQGRVEFLELSGSCVHMKWKAPKDNGGRPVTQFIVERRAVGKKSWIKIGEVDGKVT 759

Query: 703 TFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTT---V 759
            F   K+ EG AY+ RI AVN+ G+S P      F    +  PP   +   VTD T   V
Sbjct: 760 NFSTNKVEEGKAYQFRILAVNSEGVSDPLETEEVFAGNPI-EPPGFASQPQVTDVTKEAV 818

Query: 760 TMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKA 819
           T+ W  P   G A + GY++E   +G+  W+  NKD I  TK T+ GL  D +   RV A
Sbjct: 819 TITWNAPTQDGGAPVLGYIVERRKKGSNLWVPVNKDPIQGTKCTVDGLLEDTEYEFRVIA 878

Query: 820 VNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQT 855
           VN AG  +P   S  ++ K+ ++PP +    H+  +
Sbjct: 879 VNKAGPGQPSVPSSSVVAKDPVKPPGLVQDLHVSDS 914



 Score =  157 bits (397), Expect = 5e-38
 Identities = 142/589 (24%), Positives = 261/589 (44%), Gaps = 65/589 (11%)

Query: 85  FIEKPQGGTVKVGEDITFIAKVKAEDLLRKPTIKWFKGKWMDLASKAGKHLQLKETFERH 144
           F+EKPQ  T   G+   F A+V+      KP I W +   + +   A      K  ++  
Sbjct: 69  FVEKPQPVTAPEGDKAVFRARVQGN---AKPHISWKRESGIPIKESA------KIFYDSI 119

Query: 145 SRVYTFEMQIIKAKDNFAGNYRCEVTYKDKFDSCSFDLEVHESTGTTPNIDIRSAFKRSG 204
           ++ +  +++ + + D+   NY+C +   D  D+                  I +      
Sbjct: 120 NKEHVLKLEPLTSDDS--DNYKC-IASNDHADA------------------IYTVSLLVT 158

Query: 205 EGQEDAGELDFSGLLKRR-----EVKQQEEEPQVDVWELLKNAKPSEYEKIAFQYGITDL 259
           EGQE   ++DF  +LK+R     + KQ++   + ++ E+L      ++EK+  +YG TD 
Sbjct: 159 EGQE---KMDFKKMLKKRAPPAPKKKQKKVANEKEMLEILSKVPKKDFEKVCMEYGFTDF 215

Query: 260 RGMLKRLKRMRREEKKSAA--FAKILDPAYQVDKGGRVRFVVELADPKLEVKWYKNGQEI 317
           RG+L++LK M+++ +  A      + D   +VD       ++EL DP +++ W K  + +
Sbjct: 216 RGLLRKLKEMKKKVEVEAIRILKPLEDKETKVDTTVVFDCIMELKDPNVKMIWIKGTEPL 275

Query: 318 RPST---KYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTELFVREPPIMVTKQLE 374
           R      KY  +  G + +L I+N  M D   Y ++ GD++ S EL V + P+    +++
Sbjct: 276 RIQYSLGKYDVKQMGTKYMLVISNVNMNDAGIYSLSVGDKRMSAELTVLDEPLKFLGEMK 335

Query: 375 DTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKAD 434
                  +    E  +S+ + N  W  NG+E+    K    +  +G  H L I+ A  +D
Sbjct: 336 PVKVTERQTAVFEIRLSKKEPNFVWKFNGKELKRDDKYEITVSEDGLTHTLKIKDARLSD 395

Query: 435 AAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCEI-SENIPGKWTKNG 493
           + E+S         A+L++D  P+K ++ L +  V      CL+CE+ S+++  +W K+G
Sbjct: 396 SGEFSAEAGNLVQKAQLTIDRIPIKFVSNLKNVRVKERSRACLECELTSKDVTLRWKKDG 455

Query: 494 LPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFA------PDAYNVTLPAKVHVIDPP 547
             +    +  + H+G+  +L+I +A   D G+Y         P  Y  T  A V V +  
Sbjct: 456 QLLMHGTKYSMNHEGKRAELIIEDAQLSDGGEYTVVAMQDGDPTEYYST--AIVTVEERL 513

Query: 548 KIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSS 607
             +  G+   + V    G+   L + ++ E   + +W +  K I +  G ++        
Sbjct: 514 ATVKSGM---SDVHAATGSPAELCVVLNDE-KVEGVWLKDGKEITDLPG-MQIVKQGAVH 568

Query: 608 TLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPP-VAPTVTE 655
            L+      +  G Y    K    EA   I        DPP + P+V E
Sbjct: 569 KLIFPSMGPEHEGKYTFRAKGTESEASVFI-------ADPPTIDPSVLE 610



 Score = 41.6 bits (96), Expect = 0.004
 Identities = 29/95 (30%), Positives = 41/95 (43%), Gaps = 1/95 (1%)

Query: 561  TVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSG 620
            TV+ G    +     G P P     +GD  I   S +    S     TLVI      DSG
Sbjct: 1223 TVLRGQDCTMTCAFLGNPRPTVTLYKGDVNITANS-KFWYNSTSGVCTLVIPTCTLKDSG 1281

Query: 621  VYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTE 655
             Y + ++NE G+  +S  + V D  D  V  ++TE
Sbjct: 1282 DYSVLVENELGKDRSSCTLTVYDKDDKSVVASITE 1316



 Score = 30.8 bits (68), Expect = 7.7
 Identities = 27/124 (21%), Positives = 48/124 (38%), Gaps = 3/124 (2%)

Query: 1009 YFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAG 1068
            + + FS+    + E+    K S+++     + ++      D    P F +      A  G
Sbjct: 24   HVQTFSQTTKIVGEEVVRRKSSSIVEFFSLVTRSSNIPAGD--SVPEFVEKPQPVTAPEG 81

Query: 1069 YNATLNCSVRGNPKPKITWMKNK-VAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCK 1127
              A     V+GN KP I+W +   + I +  +    S      L++   +  D   Y C 
Sbjct: 82   DKAVFRARVQGNAKPHISWKRESGIPIKESAKIFYDSINKEHVLKLEPLTSDDSDNYKCI 141

Query: 1128 AVND 1131
            A ND
Sbjct: 142  ASND 145


>gi|110349719 titin isoform N2-A [Homo sapiens]
          Length = 33423

 Score =  299 bits (766), Expect = 9e-81
 Identities = 218/756 (28%), Positives = 346/756 (45%), Gaps = 52/756 (6%)

Query: 297   FVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKC 356
             F  +L+  K  VKWY+NG+EI+   KY FE  G    L I +C++ D+ EY     D K 
Sbjct: 12842 FSCQLSREKANVKWYRNGREIKEGKKYKFEKDGSIHRLIIKDCRLDDECEYACGVEDRKS 12901

Query: 357   STELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRI 416
                LFV E P+ + +  +D     G  V    E+++D   V+W +N   ++ G K  +++
Sbjct: 12902 RARLFVEEIPVEIIRPPQDILEAPGADVVFLAELNKDKVEVQWLRNNMVVVQGDK--HQM 12959

Query: 417   RVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEIC 476
               EGK H L I      D  EY  +    ++ AKL +   P KI T   D  V++GK + 
Sbjct: 12960 MSEGKIHRLQICDIKPRDQGEYRFIAKDKEARAKLELAAAP-KIKTADQDLVVDVGKPLT 13018

Query: 477   LKC--EISENIPGKWTKNGLPV----------QESDRL---KVVHKGRIHKLVIANALTE 521
             +    +       +W K   P+          Q S R+   K   KGR +K+V+ N   +
Sbjct: 13019 MVVPYDAYPKAEAEWFKENEPLSTKTIDTTAEQTSFRILEAKKGDKGR-YKIVLQNKHGK 13077

Query: 522   DEGDYVFAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPK 581
              EG                + VID P  + +    + T T      L  E P++      
Sbjct: 13078 AEGFI-------------NLKVIDVPGPVRN---LEVTETFDGEVSLAWEEPLTDGGSKI 13121

Query: 582   AMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAG-----EAHAS 636
               +    + I   +  + T+        V  + +     ++ ++ +N  G     E    
Sbjct: 13122 IGYVVERRDIKRKTWVLATDRAESCEFTVTGLQKGGVEYLFRVSARNRVGTGEPVETDNP 13181

Query: 637   IKVKV-VDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLN 695
             ++ +   D P PP+  T+T+V      + WEPP YDGG+ I  Y IE + K S RW    
Sbjct: 13182 VEARSKYDVPGPPLNVTITDVNRFGVSLTWEPPEYDGGAEITNYVIELRDKTSIRWDTAM 13241

Query: 696   FDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFV----PLAVTSPPTLLTV 751
                 ++ +     ++EG  Y  R+ A N IG+ KPS  + PFV    P+   SPP  LT 
Sbjct: 13242 TVRAEDLSATVTDVVEGQEYSFRVRAQNRIGVGKPSAAT-PFVKVADPIERPSPPVNLTS 13300

Query: 752   DSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDA 811
                T ++V ++W PP   G + + GY++E C EG ++WI  N  L+ +  + +TGL    
Sbjct: 13301 SDQTQSSVQLKWEPPLKDGGSPILGYIIERCEEGKDNWIRCNMKLVPELTYKVTGLEKGN 13360

Query: 812   KIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQ 871
             K   RV A N AG S+P     P+   +    P + +    K      V   + +++P  
Sbjct: 13361 KYLYRVSAENKAGVSDPSEILGPLTADDAFVEPTMDLSA-FKDGLEVIVPNPITILVPST 13419

Query: 872   GKPRPELTWKKDGAEIDK-NQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETAS 930
             G PRP  TW      ++  +++ ++       + I  +ERS  G Y L  K++  V+T S
Sbjct: 13420 GYPRPTATWCFGDKVLETGDRVKMKTLSAYAELVISPSERSDKGIYTL--KLENRVKTIS 13477

Query: 931   --IDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTV 988
               ID+ +I RP  P+ +K  D+  ++V LTW PP DDG + +TGY ++K +     W  V
Sbjct: 13478 GEIDVNVIARPSAPKELKFGDITKDSVHLTWEPPDDDGGSPLTGYVVEKREVSRKTWTKV 13537

Query: 989   IEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDA 1024
             ++       T+ +LV G EY F+V + N CG  E A
Sbjct: 13538 MDFVTDLEFTVPDLVQGKEYLFKVCARNKCGPGEPA 13573



 Score =  288 bits (737), Expect = 2e-77
 Identities = 165/503 (32%), Positives = 269/503 (53%), Gaps = 17/503 (3%)

Query: 536   TLPAKVHV---IDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIM 592
             TLP  V     I+PP+I LD  D    V + A   LRL + I G P P+  W + +  + 
Sbjct: 25091 TLPGSVVAQERIEPPEIELDA-DLRKVVVLRASATLRLFVTIKGRPEPEVKWEKAEGILT 25149

Query: 593   EGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPT 652
             +   R + E     + LVID   R DSG Y++ L+N +G   A + V+V+D P  PV  T
Sbjct: 25150 D---RAQIEVTSSFTMLVIDNVTRFDSGRYNLTLENNSGSKTAFVNVRVLDSPSAPVNLT 25206

Query: 653   VTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEG 712
             + EV  D   ++WEPP  DGG+ I  Y +E+++     +  +  + C +TTF  + + EG
Sbjct: 25207 IREVKKDSVTLSWEPPLIDGGAKITNYIVEKRETTRKAYATITNN-CTKTTFRIENLQEG 25265

Query: 713   VAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAA 772
              +Y  R+ A N  GI  P+  + P        PP  +T+  VT  T T++W  P+  G +
Sbjct: 25266 CSYYFRVLASNEYGIGLPAETTEPVKVSEPPLPPGRVTLVDVTRNTATIKWEKPESDGGS 25325

Query: 773   GLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYS 832
              + GYV+E   +G+E W    +  +   + TI+GL    +   RV AVN  G S+P+   
Sbjct: 25326 KITGYVVEMQTKGSEKWSTCTQ--VKTLEATISGLTAGEEYVFRVAAVNEKGRSDPRQLG 25383

Query: 833   QPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEI-DKNQ 891
              P++ ++I   P + +P H   T+  +  E + + +PF+G+P+  + W+KDG  + +  +
Sbjct: 25384 VPVIARDIEIKPSVELPFH---TFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTR 25440

Query: 892   INIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVW 951
             +N+ +S+T T + I++A +   G Y+L V       T  I I ++DRPGPP  ++I++V 
Sbjct: 25441 VNVSSSKTVTSLSIKEASKEDVGTYELCVSNSAGSITVPITIIVLDRPGPPGPIRIDEVS 25500

Query: 952   GENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFR 1011
              +++ ++W PP+ DG   I+ Y ++K +  S  W  V +   RTS  I  L  G+EY FR
Sbjct: 25501 CDSITISWNPPEYDGGCQISNYIVEKKETTSTTWHIVSQAVARTSIKIVRLTTGSEYQFR 25560

Query: 1012  VFSENMCGLSEDATMTKESAVIA 1034
             V +EN  G S   + ++ SAV+A
Sbjct: 25561 VCAENRYGKS---SYSESSAVVA 25580



 Score =  276 bits (707), Expect = 6e-74
 Identities = 176/570 (30%), Positives = 286/570 (50%), Gaps = 35/570 (6%)

Query: 463   PLTDQTVNLGKEICLKCEISENIPGKWTKNGLPVQ------ESDRLKVVHKGRIHKLVIA 516
             P+ D    +   I  KC++S    G+WT    P        E ++L   H+       I 
Sbjct: 22861 PIYDGGCEIQGYIVEKCDVSV---GEWTMCTPPTGINKTNIEVEKLLEKHEYNFRICAIN 22917

Query: 517   NALTEDEGDYVFAPDAYNVTLPAKVHV---IDPPKIILDGLDADNTVTVIAGNKLRLEIP 573
              A   +  D           +P  + V   ++ P I LD L+    + + AG  LRL +P
Sbjct: 22918 KAGVGEHAD-----------VPGPIIVEEKLEAPDIDLD-LELRKIINIRAGGSLRLFVP 22965

Query: 574   ISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEA 633
             I G P P+  W + D  I + +    T S+   ++LV+D   R DSG Y + L+N +G  
Sbjct: 22966 IKGRPTPEVKWGKVDGEIRDAAIIDVTSSF---TSLVLDNVNRYDSGKYTLTLENSSGTK 23022

Query: 634   HASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMR 693
              A + V+V+D P PPV   VTE+  D   + WEPP  DGGS I  Y +E+++     +  
Sbjct: 23023 SAFVTVRVLDTPSPPVNLKVTEITKDSVSITWEPPLLDGGSKIKNYIVEKREATRKSYAA 23082

Query: 694   LNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDS 753
             +  + C + +++  ++ EG +Y  R+ A N  GI  P+  + P     V  PP  +TVD 
Sbjct: 23083 VVTN-CHKNSWKIDQLQEGCSYYFRVTAENEYGIGLPAQTADPIKVAEVPQPPGKITVDD 23141

Query: 754   VTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKI 813
             VT  +V++ W  P+H G + +  Y++E   + +E W    +  +   +  IT L    + 
Sbjct: 23142 VTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKHSEKWSECAR--VKSLQAVITNLTQGEEY 23199

Query: 814   FVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGK 873
               RV AVN  G S+P+  + PI+ K+++  P +   +    +Y  +VG+ + + +P  G+
Sbjct: 23200 LFRVVAVNEKGRSDPRSLAVPIVAKDLVIEPDV---KPAFSSYSVQVGQDLKIEVPISGR 23256

Query: 874   PRPELTWKKDGAEIDK-NQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASID 932
             P+P +TW KDG  + +  +IN+ +S   T + I++  +   G+Y + V      +TASI+
Sbjct: 23257 PKPTITWTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQYGITVANVVGQKTASIE 23316

Query: 933   IQIIDRPGPPQ-IVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEH 991
             I  +D+P PP+  VK +DV  E++ L+W PP   G   IT Y +QK D  +  W  V   
Sbjct: 23317 IVTLDKPDPPKGPVKFDDVSAESITLSWNPPLYTGGCQITNYIVQKRDTTTTVWDVVSAT 23376

Query: 992   YHRTSATITELVIGNEYYFRVFSENMCGLS 1021
               RT+  +T+L  G EY FR+F+EN  G S
Sbjct: 23377 VARTTLKVTKLKTGTEYQFRIFAENRYGQS 23406



 Score =  272 bits (695), Expect = 2e-72
 Identities = 159/562 (28%), Positives = 280/562 (49%), Gaps = 19/562 (3%)

Query: 544   IDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESY 603
             ++ P++ LD  +    + V AG   R+ IP  G P P+  WSR +    E + +++ E  
Sbjct: 24019 LEAPELDLDS-ELRKGIVVRAGGSARIHIPFKGRPTPEITWSREEG---EFTDKVQIEKG 24074

Query: 604   PDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIM 663
              + + L ID  +R+D+G Y + L+N +G   A + VKV+D P PP    V EV  D   +
Sbjct: 24075 VNYTQLSIDNCDRNDAGKYILKLENSSGSKSAFVTVKVLDTPGPPQNLAVKEVRKDSAFL 24134

Query: 664   NWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVN 723
              WEPP  DGG+ +  Y I++++     +  ++   C +T+F+ + + EG  Y  R+ A N
Sbjct: 24135 VWEPPIIDGGAKVKNYVIDKRESTRKAYANVS-SKCSKTSFKVENLTEGAIYYFRVMAEN 24193

Query: 724   AIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCF 783
               G+  P             SPP  +T+  V+ T+ ++ W  P+H G + + GYV+E   
Sbjct: 24194 EFGVGVPVETVDAVKAAEPPSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVEMQP 24253

Query: 784   EGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEP 843
             +GTE W +  +  +      +TGL +  +   RVKA N  G S+P+    P++ K++   
Sbjct: 24254 KGTEKWSIVAESKV--CNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQ 24311

Query: 844   PKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDK-NQINIRNSETDTI 902
             P +++P +   TY  + GE + + IP  G+PRP ++W KDG  + +  ++N+  + T T+
Sbjct: 24312 PSLKLPFN---TYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTV 24368

Query: 903   IFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPP-QIVKIEDVWGENVALTWTP 961
             + I++  +   GKY +         T ++ + ++++PGPP   V+ ++V  + V ++W P
Sbjct: 24369 LHIKEGNKDDFGKYTVTATNSAGTATENLSVIVLEKPGPPVGPVRFDEVSADFVVISWEP 24428

Query: 962   PKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLS 1021
             P   G   I+ Y ++K D  +  W  V     RT+  IT+L  G EY FR+F+EN  G S
Sbjct: 24429 PAYTGGCQISNYIVEKRDTTTTTWHMVSATVARTTIKITKLKTGTEYQFRIFAENRYGKS 24488

Query: 1022  EDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNAT--LNCSVRG 1079
               A +  ++ ++      +K P      F  +    Q LV  +       T  +   +  
Sbjct: 24489 --APLDSKAVIVQYP---FKEPGPPGTPFVTSISKDQMLVQWHEPVNDGGTKIIGYHLEQ 24543

Query: 1080  NPKPKITWMKNKVAIVDDPRYR 1101
               K  I W+K     + D +++
Sbjct: 24544 KEKNSILWVKLNKTPIQDTKFK 24565



 Score =  258 bits (658), Expect = 3e-68
 Identities = 148/478 (30%), Positives = 252/478 (52%), Gaps = 12/478 (2%)

Query: 546   PPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPD 605
             PP+I LD  D    VT+ A   LRL +PI G P P+  W+R     ++ +    T SY  
Sbjct: 21857 PPEIELDA-DLRKVVTIRACCTLRLFVPIKGRPAPEVKWARDHGESLDKASIESTSSY-- 21913

Query: 606   SSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNW 665
              + L++    R DSG Y + ++N +G   A + V+V+D P PP    V EV      + W
Sbjct: 21914 -TLLIVGNVNRFDSGKYILTVENSSGSKSAFVNVRVLDTPGPPQDLKVKEVTKTSVTLTW 21972

Query: 666   EPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAI 725
             +PP  DGGS I  Y +E+++     +  +  + C +T+++  ++ EG +Y  R+ A N  
Sbjct: 21973 DPPLLDGGSKIKNYIVEKRESTRKAYSTVATN-CHKTSWKVDQLQEGCSYYFRVLAENEY 22031

Query: 726   GISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEG 785
             GI  P+  +          PP  +T+  VT  +V++ W  P+H G + + GY++E   +G
Sbjct: 22032 GIGLPAETAESVKASERPLPPGKITLMDVTRNSVSLSWEKPEHDGGSRILGYIVEMQTKG 22091

Query: 786   TEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPK 845
             ++ W  A    +  T+ TITGL    +   RV A N  G S+P+  S P++ K+++ PP 
Sbjct: 22092 SDKW--ATCATVKVTEATITGLIQGEEYSFRVSAQNEKGISDPRQLSVPVIAKDLVIPPA 22149

Query: 846   IRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDK-NQINIRNSETDTIIF 904
              ++   L  T+    GE + + +PF G+P P +TW KD   + +  ++N  ++E ++++ 
Sbjct: 22150 FKL---LFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAESTENNSLLT 22206

Query: 905   IRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQ-IVKIEDVWGENVALTWTPPK 963
             I+ A R   G Y +++         ++++ ++D+PGPP   VK+++V  +++ L+W PPK
Sbjct: 22207 IKDACREDVGHYVVKLTNSAGEAIETLNVIVLDKPGPPTGPVKMDEVTADSITLSWGPPK 22266

Query: 964   DDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLS 1021
              DG ++I  Y ++K D  +  W  V     RT+     L  G EY FR+ +EN  G S
Sbjct: 22267 YDGGSSINNYIVEKRDTSTTTWQIVSATVARTTIKACRLKTGCEYQFRIAAENRYGKS 22324



 Score =  255 bits (651), Expect = 2e-67
 Identities = 157/482 (32%), Positives = 251/482 (52%), Gaps = 13/482 (2%)

Query: 547   PKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDS 606
             P + LD    D  V V AG  +R+   +SG+PPP   W+  ++ + + +     E+   S
Sbjct: 16522 PDLQLDASVRDRIV-VHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEA---TIETTAIS 16577

Query: 607   STLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTE-VGDDWCIMNW 665
             S++VI   +R   GVY +  KNEAGE   +I V V+D P P   P +   + ++ C + W
Sbjct: 16578 SSMVIKNCQRSHQGVYSLLAKNEAGERKKTIIVDVLDVPGPVGTPFLAHNLTNESCKLTW 16637

Query: 666   EPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAI 725
               P  DGGSPI  Y IE+++     W  + + + ++     + +I+G AY  RI A N+I
Sbjct: 16638 FSPEDDGGSPITNYVIEKRESDRRAWTPVTYTVTRQNA-TVQGLIQGKAYFFRIAAENSI 16696

Query: 726   GISKPSMPSRPFV---PLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYC 782
             G+      S   V   P+ V   P  L V  VT  TVT+ W PP + G + +  YVLE  
Sbjct: 16697 GMGPFVETSEALVIREPITVPERPEDLEVKEVTKNTVTLTWNPPKYDGGSEIINYVLESR 16756

Query: 783   FEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIE 842
               GTE +     D +   K+T+ GL        RV AVN  G  +P + ++PI  K+ + 
Sbjct: 16757 LIGTEKFHKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGKPSFCTKPITCKDELA 16816

Query: 843   PPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEI-DKNQINIRNSETDT 901
             PP + +    K T   RVGEA  L   + GKP+P+++W KD A++ + ++ +I+ +    
Sbjct: 16817 PPTLHLDFRDKLTI--RVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATL 16874

Query: 902   IIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPP-QIVKIEDVWGENVALTWT 960
              +   KA+RS SGKY + V+           + ++DRPGPP   V  ++V  + + ++W 
Sbjct: 16875 ALEKIKAKRSDSGKYCVVVENSTGSRKGFCQVNVVDRPGPPVGPVSFDEVTKDYMVISWK 16934

Query: 961   PPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGL 1020
             PP DDG + IT Y I+K +     W  V     +T+  +++L+ G +Y FR+ +EN+ G+
Sbjct: 16935 PPLDDGGSKITNYIIEKKEVGKDVWMPVTSASAKTTCKVSKLLEGKDYIFRIHAENLYGI 16994

Query: 1021  SE 1022
             S+
Sbjct: 16995 SD 16996



 Score =  255 bits (651), Expect = 2e-67
 Identities = 143/470 (30%), Positives = 242/470 (51%), Gaps = 16/470 (3%)

Query: 559   TVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSS----TLVIDIA 614
             T+ V AG    + +P  G P P  +WS+ D  +       RT +Y D++    +L I+ A
Sbjct: 26195 TLIVKAGASFTMTVPFRGRPVPNVLWSKPDTDL-------RTRAYVDTTDSRTSLTIENA 26247

Query: 615   ERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGS 674
              R+DSG Y + ++N    A  ++ VKV+D P PP   TV +V  +  +++W+ P  DGG+
Sbjct: 26248 NRNDSGKYTLTIQNVLSAASLTLVVKVLDTPGPPTNITVQDVTKESAVLSWDVPENDGGA 26307

Query: 675   PILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPS 734
             P+  Y IE+++     W+ +  + C   +++   + EG  Y  R+   N  G+  P+   
Sbjct: 26308 PVKNYHIEKREASKKAWVSVT-NNCNRLSYKVTNLQEGAIYYFRVSGENEFGVGIPAETK 26366

Query: 735   RPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANK 794
                      SPP  L V S++  +V++ W  P+H G + +  YV+E   +G ++W+    
Sbjct: 26367 EGVKITEKPSPPEKLGVTSISKDSVSLTWLKPEHDGGSRIVHYVVEALEKGQKNWVKC-- 26424

Query: 795   DLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQ 854
              +   T   ++GL  +++ F RV A N AG S+P+    P+L+KE +EPP+I +      
Sbjct: 26425 AVAKSTHHVVSGLRENSEYFFRVFAENQAGLSDPRELLLPVLIKEQLEPPEIDMKNFPSH 26484

Query: 855   TYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKN-QINIRNSETDTIIFIRKAERSHS 913
             T   R G  + + IP  GKP P++T  +DG  +    + N   +  +  I ++++  + +
Sbjct: 26485 TVYVRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADA 26544

Query: 914   GKYDLQVKVDKFVETASIDIQIIDRPGPPQ-IVKIEDVWGENVALTWTPPKDDGNAAITG 972
             G+Y++          A I+I ++DRPGPP   V I D+  E+V L W PPK DG + +T 
Sbjct: 26545 GRYEITAANSSGTTKAFINIVVLDRPGPPTGPVVISDITEESVTLKWEPPKYDGGSQVTN 26604

Query: 973   YTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSE 1022
             Y + K +  +  W  V     RT   + +L  G EY FR+ +EN  G+S+
Sbjct: 26605 YILLKRETSTAVWTEVSATVARTMMKVMKLTTGEEYQFRIKAENRFGISD 26654



 Score =  252 bits (644), Expect = 1e-66
 Identities = 152/470 (32%), Positives = 240/470 (51%), Gaps = 10/470 (2%)

Query: 555   DADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIA 614
             D   TVT+ AG  LRL + +SG PPP   WS+    +   +    TESY   S L++D  
Sbjct: 29451 DLKKTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAIIDTTESY---SLLIVDKV 29507

Query: 615   ERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGS 674
              R D+G Y I  +N++G+  A++ VKV D P P  +  V EV  D   + WE P  DGG+
Sbjct: 29508 NRYDAGKYTIEAENQSGKKSATVLVKVYDTPGPCPSVKVKEVSRDSVTITWEIPTIDGGA 29567

Query: 675   PILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPS 734
             P+  Y +E K++ + R  +     C +T +    ++EG  Y  R+   N  GI +P   S
Sbjct: 29568 PVNNYIVE-KREAAMRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYGIGEPCETS 29626

Query: 735   RPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDW--IVA 792
                +   V   P  L V  VT +TVT+ W  P + G + L GYVLE C  GTE W  +V 
Sbjct: 29627 DAVLVSEVPLVPAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGTERWMKVVT 29686

Query: 793   NKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHL 852
              K  +   + T+T L    +   R++A N  G SEP+     + V+++   P I +    
Sbjct: 29687 LKPTV--LEHTVTSLNEGEQYLFRIRAQNEKGVSEPRETVTAVTVQDLRVLPTIDLSTMP 29744

Query: 853   KQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEI-DKNQINIRNSETDTIIFIRKAERS 911
             ++T     G  V LVIP  G+P P  +W   G+++ +  ++ +        + IR+    
Sbjct: 29745 QKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAKLTIRETTIR 29804

Query: 912   HSGKYDLQVKVDKFVETASIDIQIIDRPGPPQ-IVKIEDVWGENVALTWTPPKDDGNAAI 970
              +G+Y L++K      + +I + I+D+PGPP   +KI+++   ++ ++W PP+ DG A +
Sbjct: 29805 DTGEYTLELKNVTGTTSETIKVIILDKPGPPTGPIKIDEIDATSITISWEPPELDGGAPL 29864

Query: 971   TGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGL 1020
             +GY +++ D     W  V E   R++   T L  GNEY FRV + N  G+
Sbjct: 29865 SGYVVEQRDAHRPGWLPVSESVTRSTFKFTRLTEGNEYVFRVAATNRFGI 29914



 Score =  249 bits (636), Expect = 1e-65
 Identities = 151/508 (29%), Positives = 245/508 (48%), Gaps = 22/508 (4%)

Query: 533   YNVTLPAKVHVIDPPKIILDGLDADNT--------------VTVIAGNKLRLEIPISGEP 578
             Y V+   K  V DP +I L  L AD+               + VI  N + + +P +G P
Sbjct: 13364 YRVSAENKAGVSDPSEI-LGPLTADDAFVEPTMDLSAFKDGLEVIVPNPITILVPSTGYP 13422

Query: 579   PPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIK 638
              P A W  GDK ++E   R++ ++    + LVI  +ER D G+Y + L+N        I 
Sbjct: 13423 RPTATWCFGDK-VLETGDRVKMKTLSAYAELVISPSERSDKGIYTLKLENRVKTISGEID 13481

Query: 639   VKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDL 698
             V V+  P  P      ++  D   + WEPP  DGGSP+ GY +E+++     W ++  D 
Sbjct: 13482 VNVIARPSAPKELKFGDITKDSVHLTWEPPDDDGGSPLTGYVVEKREVSRKTWTKV-MDF 13540

Query: 699   CKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPF---VPLAVTSPPTLLTVDSVT 755
               +  F    +++G  Y  ++ A N  G  +P+    P     P  V  PP  +     T
Sbjct: 13541 VTDLEFTVPDLVQGKEYLFKVCARNKCGPGEPAYVDEPVNMSTPATVPDPPENVKWRDRT 13600

Query: 756   DTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFV 815
               ++ + W PP + G + + GY++E C  G++ W+   +  + +TK  +TGL        
Sbjct: 13601 ANSIFLTWDPPKNDGGSRIKGYIVERCPRGSDKWVACGEP-VAETKMEVTGLEEGKWYAY 13659

Query: 816   RVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPR 875
             RVKA+N  GAS+P   ++ I   +  E P+I +   L      + G  + L     GKP 
Sbjct: 13660 RVKALNRQGASKPSRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPE 13719

Query: 876   PELTWKKDGAEIDKN-QINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQ 934
             P++TW K    + ++ +I I N    + + I  ++RS +G Y ++        TA +++ 
Sbjct: 13720 PKITWTKADMILKQDKRITIENVPKKSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVN 13779

Query: 935   IIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHR 994
             ++D+PGPP    I DV  E+  LTW PP+DDG + IT Y +++    S  W  +      
Sbjct: 13780 VLDKPGPPAAFDITDVTNESCLLTWNPPRDDGGSKITNYVVERRATDSEVWHKLSSTVKD 13839

Query: 995   TSATITELVIGNEYYFRVFSENMCGLSE 1022
             T+   T+L+   EY FRV +ENM G+ E
Sbjct: 13840 TNFKATKLIPNKEYIFRVAAENMYGVGE 13867



 Score =  247 bits (631), Expect = 4e-65
 Identities = 170/584 (29%), Positives = 278/584 (47%), Gaps = 33/584 (5%)

Query: 461   LTPLTDQTVNL--GKEICLKCEISENIP--GKWTKNGLPVQESDRLKVVHKGRIHKLVIA 516
             L+ +  +T+++  G+ + L   I+   P    W   G  ++ES+R+ V    ++ KL I 
Sbjct: 29740 LSTMPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAKLTIR 29799

Query: 517   NALTEDEGDYVFAPDAYNVTLPA----KVHVIDPP-----KIILDGLDADNTVTVIAGNK 567
                  D G+Y    +  NVT       KV ++D P      I +D +DA +        +
Sbjct: 29800 ETTIRDTGEYTL--ELKNVTGTTSETIKVIILDKPGPPTGPIKIDEIDATSITISWEPPE 29857

Query: 568   LRLEIPISG-----EPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVY 622
             L    P+SG         +  W    +++   + +    +  +     +    R   G Y
Sbjct: 29858 LDGGAPLSGYVVEQRDAHRPGWLPVSESVTRSTFKFTRLTEGNEYVFRVAATNRFGIGSY 29917

Query: 623   HINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIE 682
                L++E  E  +SI++     P PP    + +V  D   + W PP  DGGS + GY +E
Sbjct: 29918 ---LQSEVIECRSSIRI-----PGPPETLQIFDVSRDGMTLTWYPPEDDGGSQVTGYIVE 29969

Query: 683   RKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAV 742
             RK+ ++ RW+R+N      T +    + EG+ YE R+ A+NA G  KPS PS+P V +  
Sbjct: 29970 RKEVRADRWVRVNKVPVTMTRYRSTGLTEGLEYEHRVTAINARGSGKPSRPSKPIVAMDP 30029

Query: 743   TSPPTLLTVDSVTDTT---VTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDK 799
              +PP       VTDTT   V++ W  P+  G + + GY++E       +W   N      
Sbjct: 30030 IAPPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTKCNTTPTKI 30089

Query: 800   TKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRR 859
              ++T+T LP  A+   RV A NA G  EP      + V E++E P   +    ++    R
Sbjct: 30090 REYTLTHLPQGAEYRFRVLACNAGGPGEPAEVPGTVKVTEMLEYPDYELDERYQEGIFVR 30149

Query: 860   VGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQ 919
              G  + L IP +GKP P   W K+G +I K  + I  SET T + I++A+R  SG YDL 
Sbjct: 30150 QGGVIRLTIPIKGKPFPICKWTKEGQDISKRAM-IATSETHTELVIKEADRGDSGTYDLV 30208

Query: 920   VKVDKFVETASIDIQIIDRPGPPQ-IVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKA 978
             ++     +   I +++I  P  P+  ++ +D+   +V ++W PP DDG A I GY +++ 
Sbjct: 30209 LENKCGKKAVYIKVRVIGSPNSPEGPLEYDDIQVRSVRVSWRPPADDGGADILGYILERR 30268

Query: 979   DKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSE 1022
             +     W+T+      TS  +  L    EY+FRV +EN  G+S+
Sbjct: 30269 EVPKAAWYTIDSRVRGTSLVVKGLKENVEYHFRVSAENQFGISK 30312



 Score =  245 bits (626), Expect = 2e-64
 Identities = 153/493 (31%), Positives = 238/493 (48%), Gaps = 17/493 (3%)

Query: 543   VIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRG--DKAIMEGSGRIRT 600
             +++PP+I LD       V V AG  +RL   + G P PK  W +   D  + +G    + 
Sbjct: 18600 ILEPPEIDLDA-SMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVVRKG----QV 18654

Query: 601   ESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDW 660
             +     + LVI  + RDDSG Y + L N AGE    + V+V+D P P     V++V    
Sbjct: 18655 DLVDTMAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFVNVRVLDTPGPVSDLKVSDVTKTS 18714

Query: 661   CIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIF 720
             C ++W PP  DGGS +  Y +E+++     W  +  ++ K+T+F    ++ G  Y  R+ 
Sbjct: 18715 CHVSWAPPENDGGSQVTHYIVEKREADRKTWSTVTPEV-KKTSFHVTNLVPGNEYYFRVT 18773

Query: 721   AVNAIGISKPSMPSRPFV---PLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGY 777
             AVN  G   P+   +P +   PL+   PP  L V  +T  + T+ W PP   G A +DGY
Sbjct: 18774 AVNEYGPGVPTDVPKPVLASDPLSEPDPPRKLEVTEMTKNSATLAWLPPLRDGGAKIDGY 18833

Query: 778   VLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILV 837
             +  Y  E           ++      +TGL    K   RV A NA G S P+        
Sbjct: 18834 ITSYREEEQPADRWTEYSVVKDLSLVVTGLKEGKKYKFRVAARNAVGVSLPREAEGVYEA 18893

Query: 838   KEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAE-IDKNQINIRN 896
             KE + PPKI +P  +      + G+ + +     GKP P   WKK   E +  + + +  
Sbjct: 18894 KEQLLPPKILMPEQI----TIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHK 18949

Query: 897   SETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQ-IVKIEDVWGENV 955
             +++ +I+ I+   R  SG Y L  +     +T  I + ++D PGPPQ    I D+  +  
Sbjct: 18950 ADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPGPPQPPFDISDIDADAC 19009

Query: 956   ALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSE 1015
             +L+W  P +DG + IT Y ++K D    +W T +    +TS  + +L+ G EY FRV +E
Sbjct: 19010 SLSWHIPLEDGGSNITNYIVEKCDVSRGDWVTALASVTKTSCRVGKLIPGQEYIFRVRAE 19069

Query: 1016  NMCGLSEDATMTK 1028
             N  G+SE  T  K
Sbjct: 19070 NRFGISEPLTSPK 19082



 Score =  243 bits (621), Expect = 6e-64
 Identities = 152/515 (29%), Positives = 259/515 (50%), Gaps = 25/515 (4%)

Query: 543   VIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTES 602
             ++ PP+  LD  D   T+ + AG  +RL +P+ G PPPK  WS+ +  + +  G +  +S
Sbjct: 19687 ILIPPEGELDA-DLRKTLILRAGVTMRLYVPVKGRPPPKITWSKPNVNLRDRIG-LDIKS 19744

Query: 603   YPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCI 662
                 + L  +   + D+G Y + L+N  G+   +I VKV+D P PPV  TV E+  D   
Sbjct: 19745 TDFDTFLRCENVNKYDAGKYILTLENSCGKKEYTIVVKVLDTPGPPVNVTVKEISKDSAY 19804

Query: 663   MNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAV 722
             + WEPP  DGGSPI+ Y ++++  +   W  +  + C +T+F    + EG +Y  R+FA 
Sbjct: 19805 VTWEPPIIDGGSPIINYVVQKRDAERKSWSTVTTE-CSKTSFRVANLEEGKSYFFRVFAE 19863

Query: 723   NAIGISKPSMPSRPFVPLAVTSPPTL-LTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEY 781
             N  GI  P   +R  V  + T  P + L V SV+ ++ ++ W+ P   G + + GYV+++
Sbjct: 19864 NEYGIGDPG-ETRDAVKASQTPGPVVDLKVRSVSKSSCSIGWKKPHSDGGSRIIGYVVDF 19922

Query: 782   CFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEII 841
               E  + W    K L    +++   L    +   RV A N  G   P   +  ++ ++ +
Sbjct: 19923 LTEENK-WQRVMKSL--SLQYSAKDLTEGKEYTFRVSAENENGEGTPSEIT--VVARDDV 19977

Query: 842   EPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKK-DGAEIDKNQINIRNSETD 900
               P + +       Y+ +      L IP +GKP P ++WKK +       ++++ +S  +
Sbjct: 19978 VAPDLDLKGLPDLCYLAKENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVESSAVN 20037

Query: 901   TIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPG-PPQIVKIEDVWGENVALTW 959
             T + +   ++S +GKY + +K     +  +I I+++ +PG P   +K ++V  E + L W
Sbjct: 20038 TTLIVYDCQKSDAGKYTITLKNVAGTKEGTISIKVVGKPGIPTGPIKFDEVTAEAMTLKW 20097

Query: 960   TPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCG 1019
              PPKDDG + IT Y ++K D  + +W T      +T+  +T L  G EY FRV +EN  G
Sbjct: 20098 APPKDDGGSEITNYILEKRDSVNNKWVTCASAVQKTTFRVTRLHEGMEYTFRVSAENKYG 20157

Query: 1020  LSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAP 1054
             + E     K   ++AR            FD  +AP
Sbjct: 20158 VGEG---LKSEPIVAR----------HPFDVPDAP 20179



 Score =  243 bits (620), Expect = 8e-64
 Identities = 202/709 (28%), Positives = 322/709 (45%), Gaps = 69/709 (9%)

Query: 357   STELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKW----FKNGEEIIP---- 408
             S  L +REP I V ++ ED        +E++ EV+++   + W    +  G EII     
Sbjct: 16705 SEALVIREP-ITVPERPED--------LEVK-EVTKNTVTLTWNPPKYDGGSEIINYVLE 16754

Query: 409   ----GPKSRYRIRVEGK-KHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTP 463
                 G +  +++  +        ++G  + D  EY V         K S   KP+     
Sbjct: 16755 SRLIGTEKFHKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGKPSFCTKPITCKDE 16814

Query: 464   LTDQTVNLGKEICLKCEISE------NIPGK------WTKNGLPVQESDRLKVVHKGRIH 511
             L   T++L     L   + E         GK      W K+   V E DR  +       
Sbjct: 16815 LAPPTLHLDFRDKLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATL 16874

Query: 512   KLVIANALTEDEGDYVFAPDAYNVTLPAK----VHVIDPPKIILDGLDADNTVTVIAGNK 567
              L    A   D G Y    +  N T   K    V+V+D P   +  +  D          
Sbjct: 16875 ALEKIKAKRSDSGKYCVVVE--NSTGSRKGFCQVNVVDRPGPPVGPVSFDEVT------- 16925

Query: 568   LRLEIPISGEPPPKAMWSRGDKAIMEGSGRIR------TESYPDSSTLVIDIAERDDSGV 621
              +  + IS +PP     S+    I+E     +      T +   ++  V  + E  D  +
Sbjct: 16926 -KDYMVISWKPPLDDGGSKITNYIIEKKEVGKDVWMPVTSASAKTTCKVSKLLEGKDY-I 16983

Query: 622   YHINLKNEAG--EAHASIKVKVVD---FPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPI 676
             + I+ +N  G  +   S  +K  D    PD P  P VTEV  D  ++ W  P +DGG PI
Sbjct: 16984 FRIHAENLYGISDPLVSDSMKAKDRFRVPDAPDQPIVTEVTKDSALVTWNKP-HDGGKPI 17042

Query: 677   LGYFIERKKKQSSRWMRLNFD-LCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSR 735
               Y +E+++  S RW R+  D +   T F    ++EG  YE R+ A N IGI  PS PS+
Sbjct: 17043 TNYILEKRETMSKRWARVTKDPIHPYTKFRVPDLLEGCQYEFRVSAENEIGIGDPSPPSK 17102

Query: 736   PFV---PLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVA 792
             P     P+A  SPP        T  +V + W+PP H G + + GY++EY   G E+W  A
Sbjct: 17103 PVFAKDPIAKPSPPVNPEAIDTTCNSVDLTWQPPRHDGGSKILGYIVEYQKVGDEEWRRA 17162

Query: 793   NK--DLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPR 850
             N   +   +TK+ +TGL        RV AVNAAG S+P +  +P+LVK+ +EPP++ +  
Sbjct: 17163 NHTPESCPETKYKVTGLRDGQTYKFRVLAVNAAGESDPAHVPEPVLVKDRLEPPELILDA 17222

Query: 851   HLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAER 910
             ++ +    +VG+ + L    +G P P++TWKK+  +    +  I  +   + + IR A  
Sbjct: 17223 NMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAP-TKARIDVTPVGSKLEIRNAAH 17281

Query: 911   SHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAI 970
                G Y L V+     +T S+ + ++D+PGPP+ +++ ++  ++  LTW  P DDG + I
Sbjct: 17282 EDGGIYSLTVENPAGSKTVSVKVLVLDKPGPPRDLEVSEIRKDSCYLTWKEPLDDGGSVI 17341

Query: 971   TGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCG 1019
             T Y +++ D  S +W  +     + S     L  GN+Y FRV +EN  G
Sbjct: 17342 TNYVVERRDVASAQWSPLSATSKKKSHFAKHLNEGNQYLFRVAAENQYG 17390



 Score =  243 bits (620), Expect = 8e-64
 Identities = 166/560 (29%), Positives = 272/560 (48%), Gaps = 26/560 (4%)

Query: 489   WTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAKVH--VIDP 546
             W K+G+ ++E  R +++       L + + +  D G YV        T    V+  V+D 
Sbjct: 25823 WAKDGIEIEERARTEIISTDNHTLLTVKDCIRRDTGQYVLTLKNVAGTRSVAVNCKVLDK 25882

Query: 547   P-----KIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTE 601
             P      + ++GL A+         +      I      K   S     I EG  ++   
Sbjct: 25883 PGPPAGPLEINGLTAEKCSLSWGRPQEDGGADIDYYIVEKRETSHLAWTICEGELQM--- 25939

Query: 602   SYPDSSTLVIDIAERDDSGVYHINLKNE--AGEAHASIKVKVVD---FPDPPVAPTVTEV 656
                 +S  V  + + ++  ++ +   N+   GE   S+ +K +D    P PP +  +T V
Sbjct: 25940 ----TSCKVTKLLKGNEY-IFRVTGVNKYGVGEPLESVAIKALDPFTVPSPPTSLEITSV 25994

Query: 657   GDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYE 716
               +   + W  P  DGGS I GY IER++K S RW+R+N     +   +   + EG  YE
Sbjct: 25995 TKESMTLCWSRPESDGGSEISGYIIERREKNSLRWVRVNKKPVYDLRVKSTGLREGCEYE 26054

Query: 717   VRIFAVNAIGISKPSMPS---RPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAG 773
              R++A NA G+S PS  S   R   P+ + SPP+   +     TT+T+ W  P   G A 
Sbjct: 26055 YRVYAENAAGLSLPSETSPLIRAEDPVFLPSPPSKPKIVDSGKTTITIAWVKPLFDGGAP 26114

Query: 774   LDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQ 833
             + GY +EY      DW  + + L   T++TI+GL T A+   RVK+VN  GAS+P   S 
Sbjct: 26115 ITGYTVEYKKSDDTDWKTSIQSLRG-TEYTISGLTTGAEYVFRVKSVNKVGASDPSDSSD 26173

Query: 834   PILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQIN 893
             P + KE  E P   I   +++T I + G +  + +PF+G+P P + W K   ++ + +  
Sbjct: 26174 PQIAKEREEEPLFDIDSEMRKTLIVKAGASFTMTVPFRGRPVPNVLWSKPDTDL-RTRAY 26232

Query: 894   IRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGE 953
             +  +++ T + I  A R+ SGKY L ++      + ++ ++++D PGPP  + ++DV  E
Sbjct: 26233 VDTTDSRTSLTIENANRNDSGKYTLTIQNVLSAASLTLVVKVLDTPGPPTNITVQDVTKE 26292

Query: 954   NVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVF 1013
             +  L+W  P++DG A +  Y I+K +     W +V  + +R S  +T L  G  YYFRV 
Sbjct: 26293 SAVLSWDVPENDGGAPVKNYHIEKREASKKAWVSVTNNCNRLSYKVTNLQEGAIYYFRVS 26352

Query: 1014  SENMCGLSEDATMTKESAVI 1033
              EN  G+   A  TKE   I
Sbjct: 26353 GENEFGVGIPAE-TKEGVKI 26371



 Score =  241 bits (614), Expect = 4e-63
 Identities = 135/381 (35%), Positives = 198/381 (51%), Gaps = 3/381 (0%)

Query: 645   PDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTF 704
             P PP  P VT V  D   ++W  P  DGGSPILGY +ERK++    W  ++  L     F
Sbjct: 21259 PGPPGTPQVTAVTKDSMTISWHEPLSDGGSPILGYHVERKERNGILWQTVSKALVPGNIF 21318

Query: 705   EPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWR 764
             +   + +G+AYE R+ A N  G SKPS PS P + L    PP      ++T  TVT++W 
Sbjct: 21319 KSSGLTDGIAYEFRVIAENMAGKSKPSKPSEPMLALDPIDPPGKPVPLNITRHTVTLKWA 21378

Query: 765   PPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAG 824
              P++ G   +  Y++E        W+ AN   I + +FT++GL  DA    RV A NAAG
Sbjct: 21379 KPEYTGGFKITSYIVEKRDLPNGRWLKANFSNILENEFTVSGLTEDAAYEFRVIAKNAAG 21438

Query: 825   A-SEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKD 883
             A S P   S  I  ++ +E PKI++    K T I + GEA  L     G+P P + W KD
Sbjct: 21439 AISPPSEPSDAITCRDDVEAPKIKVDVKFKDTVILKAGEAFRLEADVSGRPPPTMEWSKD 21498

Query: 884   GAEIDKN-QINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPP 942
             G E++   ++ I+ ++  T +  + + R  SG Y L             +++++DRPGPP
Sbjct: 21499 GKELEGTAKLEIKIADFSTNLVNKDSTRRDSGAYTLTATNPGGFAKHIFNVKVLDRPGPP 21558

Query: 943   Q-IVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITE 1001
             +  + + +V  E   L+W PP DDG A I  Y +QK +   + W  V      T   +T+
Sbjct: 21559 EGPLAVTEVTSEKCVLSWFPPLDDGGAKIDHYIVQKRETSRLAWTNVASEVQVTKLKVTK 21618

Query: 1002  LVIGNEYYFRVFSENMCGLSE 1022
             L+ GNEY FRV + N  G+ E
Sbjct: 21619 LLKGNEYIFRVMAVNKYGVGE 21639



 Score =  240 bits (613), Expect = 5e-63
 Identities = 159/591 (26%), Positives = 282/591 (47%), Gaps = 40/591 (6%)

Query: 454   DLKPLKILTPLTDQTVNLGKEICLKCEISENIPGK--WTKNGLPVQESDRLKVVHKGRIH 511
             D+KP       +  +V +G+++ ++  IS        WTK+GLP++++ R+ V     + 
Sbjct: 23231 DVKPA-----FSSYSVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLT 23285

Query: 512   KLVIANALTEDEGDYVFAPDAYNVTLPAKVHVI-----DPPK--IILDGLDADNTVTVIA 564
              L I     +D G Y            A + ++     DPPK  +  D + A++      
Sbjct: 23286 TLSIKETHKDDGGQYGITVANVVGQKTASIEIVTLDKPDPPKGPVKFDDVSAES------ 23339

Query: 565   GNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRT-----ESYPDSSTLVIDIAERDDS 619
                    I +S  PP      +    I++      T      +    +TL +   +    
Sbjct: 23340 -------ITLSWNPPLYTGGCQITNYIVQKRDTTTTVWDVVSATVARTTLKVTKLKTGTE 23392

Query: 620   GVYHINLKNEAGEAHASIKVKVV-----DFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGS 674
               + I  +N  G++ A     +V       P PP  P  T +  D  ++ W  P  +GGS
Sbjct: 23393 YQFRIFAENRYGQSFALESDPIVAQYPYKEPGPPGTPFATAISKDSMVIQWHEPVNNGGS 23452

Query: 675   PILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPS 734
             P++GY +ERK++ S  W ++N  +  +T F+ + + EG+ YE R++A N +G+ K S  S
Sbjct: 23453 PVIGYHLERKERNSILWTKVNKTIIHDTQFKAQNLEEGIEYEFRVYAENIVGVGKASKNS 23512

Query: 735   RPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANK 794
               +V      PP       V    +T++W  P + G + + GY++E        W+ A+ 
Sbjct: 23513 ECYVARDPCDPPGTPEPIMVKRNEITLQWTKPVYDGGSMITGYIVEKRDLPDGRWMKASF 23572

Query: 795   DLIDKTKFTITGLPTDAKIFVRVKAVNAAGA-SEPKYYSQPILVKEIIEPPKIRIPRHLK 853
               + +T+FT++GL  D +   RV A NAAGA S+P   + PI  K+ +E P+I +    +
Sbjct: 23573 TNVIETQFTVSGLTEDQRYEFRVIAKNAAGAISKPSDSTGPITAKDEVELPRISMDPKFR 23632

Query: 854   QTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKN-QINIRNSETDTIIFIRKAERSH 912
              T +   GE   L     GKP P + W +   EI+++ +  I+N++   ++ ++ A R  
Sbjct: 23633 DTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRID 23692

Query: 913   SGKYDLQVKVDKFVETASIDIQIIDRPGPPQ-IVKIEDVWGENVALTWTPPKDDGNAAIT 971
              G+Y L+       ++  ++++++DRPGPP+  V++  V  E  +LTW+PP  DG + I+
Sbjct: 23693 GGQYILRASNVAGSKSFPVNVKVLDRPGPPEGPVQVTGVTSEKCSLTWSPPLQDGGSDIS 23752

Query: 972   GYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSE 1022
              Y ++K +   + W  V       S  +T+L+ GNEY FR+ + N  G+ E
Sbjct: 23753 HYVVEKRETSRLAWTVVASEVVTNSLKVTKLLEGNEYVFRIMAVNKYGVGE 23803



 Score =  239 bits (611), Expect = 8e-63
 Identities = 148/495 (29%), Positives = 245/495 (49%), Gaps = 10/495 (2%)

Query: 531   DAYNVTLPAK-VHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDK 589
             D+  VT   K V  +  P++ +D  +   T  V AG  +RL I   G P P A+WS+ D 
Sbjct: 28338 DSCEVTGTIKAVDRLTAPELDIDA-NFKQTHVVRAGASIRLFIAYQGRPTPTAVWSKPDS 28396

Query: 590   AIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPV 649
              +   +    T+S+   STL ++   R+D+G Y + ++N +G    +  VKV+D P PP 
Sbjct: 28397 NLSLRADIHTTDSF---STLTVENCNRNDAGKYTLTVENNSGSKSITFTVKVLDTPGPPG 28453

Query: 650   APTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKM 709
               T  +V      + W+ P  DGG+ I  Y +E+++     W  ++ + C    F+   +
Sbjct: 28454 PITFKDVTRGSATLMWDAPLLDGGARIHHYVVEKREASRRSWQVIS-EKCTRQIFKVNDL 28512

Query: 710   IEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHI 769
              EGV Y  R+ AVN  G+ +P     P V     +PP  L V   + ++  + W  PDH 
Sbjct: 28513 AEGVPYYFRVSAVNEYGVGEPYEMPEPIVATEQPAPPRRLDVVDTSKSSAVLAWLKPDHD 28572

Query: 770   GAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPK 829
             G + + GY+LE   +G++ W+ A      +  FT+  L    +   RVKA N AG SEP+
Sbjct: 28573 GGSRITGYLLEMRQKGSDFWVEAGH--TKQLTFTVERLVEKTEYEFRVKAKNDAGYSEPR 28630

Query: 830   YYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEI-D 888
                  +++KE    P   +     Q    + G    + +P  G+P P++TWK +   + +
Sbjct: 28631 EAFSSVIIKEPQIEPTADLTGITNQLITCKAGSPFTIDVPISGRPAPKVTWKLEEMRLKE 28690

Query: 889   KNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGP-PQIVKI 947
              ++++I  ++  T + ++ + R  SG+Y L ++    V+T S+ + +I RPGP    +++
Sbjct: 28691 TDRVSITTTKDRTTLTVKDSMRGDSGRYFLTLENTAGVKTFSVTVVVIGRPGPVTGPIEV 28750

Query: 948   EDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNE 1007
               V  E+  L+W  PKD G   IT Y ++K +  +  W  V     RT   +T L    E
Sbjct: 28751 SSVSAESCVLSWGEPKDGGGTEITNYIVEKRESGTTAWQLVNSSVKRTQIKVTHLTKYME 28810

Query: 1008  YYFRVFSENMCGLSE 1022
             Y FRV SEN  G+S+
Sbjct: 28811 YSFRVSSENRFGVSK 28825



 Score =  238 bits (608), Expect = 2e-62
 Identities = 155/491 (31%), Positives = 238/491 (48%), Gaps = 15/491 (3%)

Query: 544   IDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESY 603
             ++PP++ILD   A     +  G+ LRL   I G P PK  W + D+   +   + R +  
Sbjct: 17213 LEPPELILDANMAREQ-HIKVGDTLRLSAIIKGVPFPKVTWKKEDR---DAPTKARIDVT 17268

Query: 604   PDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIM 663
             P  S L I  A  +D G+Y + ++N AG    S+KV V+D P PP    V+E+  D C +
Sbjct: 17269 PVGSKLEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDKPGPPRDLEVSEIRKDSCYL 17328

Query: 664   NWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVN 723
              W+ P  DGGS I  Y +ER+   S++W  L+    K++ F  K + EG  Y  R+ A N
Sbjct: 17329 TWKEPLDDGGSVITNYVVERRDVASAQWSPLSATSKKKSHF-AKHLNEGNQYLFRVAAEN 17387

Query: 724   AIG---ISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLE 780
               G     +   P +   PL    PP  L    V  T V++ W  PD  G + + GY++E
Sbjct: 17388 QYGRGPFVETPKPIKALDPLHPPGPPKDLHHVDVDKTEVSLVWNKPDRDGGSPITGYLVE 17447

Query: 781   YCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEI 840
             Y  EGT+DWI      +   +  +TGL        RVKA N  G   P   + PI  +E 
Sbjct: 17448 YQEEGTQDWI--KFKTVTNLECVVTGLQQGKTYRFRVKAENIVGLGLPD-TTIPIECQEK 17504

Query: 841   IEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQ-INIRNSET 899
             + PP + +   L +  + + G  V      +G P P   W  DG+EI  ++   +     
Sbjct: 17505 LVPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNF 17564

Query: 900   DTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQ-IVKIEDVWGENVALT 958
              +++ I+   R  +G+Y + V      +T ++ + ++D PGPP   + I DV  E++ ++
Sbjct: 17565 SSVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTVLDVPGPPTGPINILDVTPEHMTIS 17624

Query: 959   WTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMC 1018
             W PPKDDG + +  Y ++K D +   W  V     +T   I  L  G EY FRV +EN  
Sbjct: 17625 WQPPKDDGGSPVINYIVEKQDTRKDTWGVVSSGSSKTKLKIPHLQKGCEYVFRVRAENKI 17684

Query: 1019  GLSE--DATMT 1027
             G+    D+T T
Sbjct: 17685 GVGPPLDSTPT 17695



 Score =  238 bits (607), Expect = 2e-62
 Identities = 169/593 (28%), Positives = 282/593 (47%), Gaps = 27/593 (4%)

Query: 266   LKRMRREEKKSAAFA-------KILDPAYQVDKGGR--VRFVVELADPKLEVKWYKNGQE 316
             L   R E  KSAA         +I++P   ++   +  V F  ++    + +KW KNG+E
Sbjct: 12713 LTNHRGENVKSAANLIVEEEDLRIVEPLKDIETMEKKSVTFWCKVNRLNVTLKWTKNGEE 12772

Query: 317   IRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTELFVREPPIMVTKQLEDT 376
             +    +  +     + +L I +C   D+ EY VTAG +K   EL + E P    + LED 
Sbjct: 12773 VPFDNRVSYRVDKYKHMLTIKDCGFPDEGEYIVTAGQDKSVAELLIIEAPTEFVEHLEDQ 12832

Query: 377   TAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAA 436
             T    +     C++S + ANVKW++NG EI  G K  Y+   +G  H LII+     D  
Sbjct: 12833 TVTEFDDAVFSCQLSREKANVKWYRNGREIKEGKK--YKFEKDGSIHRLIIKDCRLDDEC 12890

Query: 437   EYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCEIS-ENIPGKWTKNGLP 495
             EY+      +S A+L V+  P++I+ P  D     G ++    E++ + +  +W +N + 
Sbjct: 12891 EYACGVEDRKSRARLFVEEIPVEIIRPPQDILEAPGADVVFLAELNKDKVEVQWLRNNMV 12950

Query: 496   VQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKIILDGLD 555
             V + D+ +++ +G+IH+L I +    D+G+Y F   A +    AK+ +   PKI      
Sbjct: 12951 VVQGDKHQMMSEGKIHRLQICDIKPRDQGEYRFI--AKDKEARAKLELAAAPKI----KT 13004

Query: 556   ADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAE 615
             AD  + V  G  L + +P    P  +A W + ++ +   +     ++  + ++  I  A+
Sbjct: 13005 ADQDLVVDVGKPLTMVVPYDAYPKAEAEWFKENEPLSTKT----IDTTAEQTSFRILEAK 13060

Query: 616   RDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSP 675
             + D G Y I L+N+ G+A   I +KV+D P P     VTE  D    + WE P  DGGS 
Sbjct: 13061 KGDKGRYKIVLQNKHGKAEGFINLKVIDVPGPVRNLEVTETFDGEVSLAWEEPLTDGGSK 13120

Query: 676   ILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIE-GVAYEVRIFAVNAIGISKPSMPS 734
             I+GY +ER+  +   W+ L  D  +   F    + + GV Y  R+ A N +G  +P    
Sbjct: 13121 IIGYVVERRDIKRKTWV-LATDRAESCEFTVTGLQKGGVEYLFRVSARNRVGTGEPVETD 13179

Query: 735   RPFVPLA---VTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIV 791
              P    +   V  PP  +T+  V    V++ W PP++ G A +  YV+E   + +  W  
Sbjct: 13180 NPVEARSKYDVPGPPLNVTITDVNRFGVSLTWEPPEYDGGAEITNYVIELRDKTSIRWDT 13239

Query: 792   ANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPP 844
             A     +    T+T +    +   RV+A N  G  +P   +  + V + IE P
Sbjct: 13240 AMTVRAEDLSATVTDVVEGQEYSFRVRAQNRIGVGKPSAATPFVKVADPIERP 13292



 Score =  238 bits (607), Expect = 2e-62
 Identities = 172/634 (27%), Positives = 302/634 (47%), Gaps = 44/634 (6%)

Query: 411   KSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVN 470
             K++Y+ R   +  + I   +  +D    +++         LSV +K L         TV 
Sbjct: 19259 KAQYQFRAIARTAVNISPPSEPSDPV--TILAENVPPRIDLSVAMKSLL--------TVK 19308

Query: 471   LGKEICLKCEI-SENIPG-KWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVF 528
              G  +CL   +  + +P   W K+G  ++ ++ +K+  +  +  L + +   +D GDY  
Sbjct: 19309 AGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTI 19368

Query: 529   APDAYNVTLPA--KVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSR 586
               +  + +  A  K+ V+D P     G  A   +  +  ++  L    S EPP +   S 
Sbjct: 19369 TAENSSGSKSATIKLKVLDKP-----GPPASVKINKMYSDRAML----SWEPPLEDGGSE 19419

Query: 587   GDKAIMEGSGRIRTESYPDSSTLVI---DIAERDDSGVYHINL--KNEAGEA-----HAS 636
                 I++     R      S+T+ I    + +  +   Y   +  +N+ G         +
Sbjct: 19420 ITNYIVDKRETSRPNWAQVSATVPITSCSVEKLIEGHEYQFRICAENKYGVGDPVFTEPA 19479

Query: 637   IKVKVVDFP---DPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMR 693
             I     D P   DPPV   +T+   D   ++W+PPA DGGSPI GY +E+++ Q+  W +
Sbjct: 19480 IAKNPYDPPGRCDPPVISNITK---DHMTVSWKPPADDGGSPITGYLLEKRETQAVNWTK 19536

Query: 694   LNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFV---PLAVTSPPTLLT 750
             +N     E T +   + EG  YE R+ A+N  G  KPS  S+      P     PP    
Sbjct: 19537 VNRKPIIERTLKATGLQEGTEYEFRVTAINKAGPGKPSDASKAAYARDPQYPPGPPAFPK 19596

Query: 751   VDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVAN-KDLIDKTKFTITGLPT 809
             V   T ++V++ W  P + G + + GY++E     +++W+  N    + KT+F +TGL  
Sbjct: 19597 VYDTTRSSVSLSWGKPAYDGGSPIIGYLVEVKRADSDNWVRCNLPQNLQKTRFEVTGLME 19656

Query: 810   DAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIP 869
             D +   RV AVN  G S+P         K+I+ PP+  +   L++T I R G  + L +P
Sbjct: 19657 DTQYQFRVYAVNKIGYSDPSDVPDKHYPKDILIPPEGELDADLRKTLILRAGVTMRLYVP 19716

Query: 870   FQGKPRPELTWKKDGAEI-DKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVET 928
              +G+P P++TW K    + D+  ++I++++ DT +      +  +GKY L ++     + 
Sbjct: 19717 VKGRPPPKITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKYILTLENSCGKKE 19776

Query: 929   ASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTV 988
              +I ++++D PGPP  V ++++  ++  +TW PP  DG + I  Y +QK D +   W TV
Sbjct: 19777 YTIVVKVLDTPGPPVNVTVKEISKDSAYVTWEPPIIDGGSPIINYVVQKRDAERKSWSTV 19836

Query: 989   IEHYHRTSATITELVIGNEYYFRVFSENMCGLSE 1022
                  +TS  +  L  G  Y+FRVF+EN  G+ +
Sbjct: 19837 TTECSKTSFRVANLEEGKSYFFRVFAENEYGIGD 19870



 Score =  238 bits (606), Expect = 3e-62
 Identities = 182/680 (26%), Positives = 309/680 (45%), Gaps = 62/680 (9%)

Query: 389   EVSEDDANVKWFK----NGEEII-------PGPKSRYRIRVEGKKHILIIEGATKADAAE 437
             +VS+  A++ W K     G  ++       P    ++ I  E K    ++ G +     +
Sbjct: 24223 DVSQTSASLMWEKPEHDGGSRVLGYVVEMQPKGTEKWSIVAESKVCNAVVTGLSSGQEYQ 24282

Query: 438   YSVMTTG--GQSSAKL--------SVDLKPLKILTPLTDQTVNLGKEICLKCEI----SE 483
             + V      G+S  ++         + ++P  +  P    ++  G+++ ++  +      
Sbjct: 24283 FRVKAYNEKGKSDPRVLGVPVIAKDLTIQP-SLKLPFNTYSIQAGEDLKIEIPVIGRPRP 24341

Query: 484   NIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAP--DAYNVTLPAKV 541
             NI   W K+G P++++ R+ V        L I     +D G Y       A   T    V
Sbjct: 24342 NI--SWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKYTVTATNSAGTATENLSV 24399

Query: 542   HVIDPP-----KIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSG 596
              V++ P      +  D + AD  V             IS EPP      +    I+E   
Sbjct: 24400 IVLEKPGPPVGPVRFDEVSADFVV-------------ISWEPPAYTGGCQISNYIVEKRD 24446

Query: 597   RIRTESYPDSSTLV---IDIAERDDSGVYHINL--KNEAGE-AHASIKVKVVDFP----D 646
                T  +  S+T+    I I +      Y   +  +N  G+ A    K  +V +P     
Sbjct: 24447 TTTTTWHMVSATVARTTIKITKLKTGTEYQFRIFAENRYGKSAPLDSKAVIVQYPFKEPG 24506

Query: 647   PPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEP 706
             PP  P VT +  D  ++ W  P  DGG+ I+GY +E+K+K S  W++LN    ++T F+ 
Sbjct: 24507 PPGTPFVTSISKDQMLVQWHEPVNDGGTKIIGYHLEQKEKNSILWVKLNKTPIQDTKFKT 24566

Query: 707   KKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPP 766
               + EG+ YE ++ A N +GI KPS  S  FV      PP       +T   VT++W+ P
Sbjct: 24567 TGLDEGLEYEFKVSAENIVGIGKPSKVSECFVARDPCDPPGRPEAIVITRNNVTLKWKKP 24626

Query: 767   DHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAG-A 825
              + G + + GY++E        W+ A+   + +T+FT++GL  D +   RV A NAAG  
Sbjct: 24627 AYDGGSKITGYIVEKKDLPDGRWMKASFTNVLETEFTVSGLVEDQRYEFRVIARNAAGNF 24686

Query: 826   SEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGA 885
             SEP   S  I  ++ I+ P   +    K   +   GE   L    +GKP P++ W KDG 
Sbjct: 24687 SEPSDSSGAITARDEIDAPNASLDPKYKDVIVVHAGETFVLEADIRGKPIPDVVWSKDGK 24746

Query: 886   EIDKN--QINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQ 943
             E+++   ++ I+++   T + ++   R+  G+Y L++      ++  I ++++DRPGPP+
Sbjct: 24747 ELEETAARMEIKSTIQKTTLVVKDCIRTDGGQYILKLSNVGGTKSIPITVKVLDRPGPPE 24806

Query: 944   -IVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITEL 1002
               +K+  V  E   L W PP  DG A I+ Y I+K +   + W  V       +  +T+L
Sbjct: 24807 GPLKVTGVTAEKCYLAWNPPLQDGGANISHYIIEKRETSRLSWTQVSTEVQALNYKVTKL 24866

Query: 1003  VIGNEYYFRVFSENMCGLSE 1022
             + GNEY FRV + N  G+ E
Sbjct: 24867 LPGNEYIFRVMAVNKYGIGE 24886



 Score =  234 bits (598), Expect = 3e-61
 Identities = 141/476 (29%), Positives = 240/476 (50%), Gaps = 11/476 (2%)

Query: 554   LDAD--NTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVI 611
             LDA+   T+ V AG  +R+ +PI G P P+  W++ +  +   +    TES+   + L+I
Sbjct: 20778 LDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKNRANIENTESF---TLLII 20834

Query: 612   DIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYD 671
                 R D+G + + ++N AG+    + V+V+D P P +    T++  D   ++W+ P  D
Sbjct: 20835 PECNRYDTGKFVMTIENPAGKKSGFVNVRVLDTPGPVLNLRPTDITKDSVTLHWDLPLID 20894

Query: 672   GGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPS 731
             GGS I  Y +E+++     +       C + T++   + EG  Y  R+ A N  GI +P+
Sbjct: 20895 GGSRITNYIVEKREATRKSYSTATTK-CHKCTYKVTGLSEGCEYFFRVMAENEYGIGEPT 20953

Query: 732   MPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIV 791
               + P       SPP  L +  +T +TV++ W  P H G + + GYV+E   +G++ W  
Sbjct: 20954 ETTEPVKASEAPSPPDSLNIMDITKSTVSLAWPKPKHDGGSKITGYVIEAQRKGSDQW-- 21011

Query: 792   ANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRH 851
              +   +   +  +  L    +   +V AVN+AG S P+  S+P++VKE    P++ +   
Sbjct: 21012 THITTVKGLECVVRNLTEGEEYTFQVMAVNSAGRSAPR-ESRPVIVKEQTMLPELDLRGI 21070

Query: 852   LKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQ-INIRNSETDTIIFIRKAER 910
              ++  I + G+ + + IP  G+P+P +TWKK    + + Q +N   + T TI+ I +  R
Sbjct: 21071 YQKLVIAKAGDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVR 21130

Query: 911   SHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQ-IVKIEDVWGENVALTWTPPKDDGNAA 969
             S SG Y L  +         I IQ+ D PGPP   +K ++V  + V  +W PP++DG   
Sbjct: 21131 SDSGPYPLTARNIVGEVGDVITIQVHDIPGPPTGPIKFDEVSSDFVTFSWDPPENDGGVP 21190

Query: 970   ITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDAT 1025
             I+ Y ++     S  W  +     RT+   T L  G EY FRV ++N  G+    T
Sbjct: 21191 ISNYVVEMRQTDSTTWVELATTVIRTTYKATRLTTGLEYQFRVKAQNRYGVGPGIT 21246



 Score =  233 bits (595), Expect = 6e-61
 Identities = 168/591 (28%), Positives = 280/591 (47%), Gaps = 38/591 (6%)

Query: 453   VDLKPLKILTPLTDQTVNLGKEICLKCEISENIPGKWTKNGLPVQESDRLKVVHKGRIHK 512
             +DLK   +LT     T+ L  E  ++ +    +     K+   +  S R+K+  +    K
Sbjct: 18203 LDLKLSGVLTVKAGDTIRL--EAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSK 18260

Query: 513   LVIANALTEDEGDYVFAPD--AYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRL 570
               +  A   D G YV      A +    A V+V+D P     G   +  +  ++ ++   
Sbjct: 18261 FSLTKAKRSDGGKYVVTATNTAGSFVAYATVNVLDKP-----GPVRNLKIVDVSSDRCT- 18314

Query: 571   EIPISGEPPPKAMWSRGDKAIMEG--SGRIRTESYPDS----STLVIDIAERDDSGVYHI 624
                +  +PP           I+E   + R+   +Y  +     T V  + E ++  ++ +
Sbjct: 18315 ---VCWDPPEDDGGCEIQNYILEKCETKRMVWSTYSATVLTPGTTVTRLIEGNEY-IFRV 18370

Query: 625   NLKNEAG-----EAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGY 679
               +N+ G     E+   I     D P  P  P VT+V  +   + W PP YDGG  I GY
Sbjct: 18371 RAENKIGTGPPTESKPVIAKTKYDKPGRPDPPEVTKVSKEEMTVVWNPPEYDGGKSITGY 18430

Query: 680   FIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFV- 738
             F+E+K+K S+RW+ +N     E   + + ++    Y+ R+ A N IGI +PS+PSRP V 
Sbjct: 18431 FLEKKEKHSTRWVPVNKSAIPERRMKVQNLLPDHEYQFRVKAENEIGIGEPSLPSRPVVA 18490

Query: 739   --PLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYC-----FEGTEDWIV 791
               P+    PPT   V   T  ++T+ W  P + G A + GYV+E           E W  
Sbjct: 18491 KDPIEPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAPIIGYVVEMRPKIADASPDEGWKR 18550

Query: 792   ANKDL-IDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPR 850
              N    + + +FT+T L  + +   RV A N  G   P    + I  KEI+EPP+I +  
Sbjct: 18551 CNAAAQLVRKEFTVTSLDENQEYEFRVCAQNQVGIGRPAELKEAIKPKEILEPPEIDLDA 18610

Query: 851   HLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAE--IDKNQINIRNSETDTIIFIRKA 908
              +++  I R G  + L    +G+P P++TW+K G +  + K Q+++   +T   + I  +
Sbjct: 18611 SMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVVRKGQVDL--VDTMAFLVIPNS 18668

Query: 909   ERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNA 968
              R  SGKY L +      +   ++++++D PGP   +K+ DV   +  ++W PP++DG +
Sbjct: 18669 TRDDSGKYSLTLVNPAGEKAVFVNVRVLDTPGPVSDLKVSDVTKTSCHVSWAPPENDGGS 18728

Query: 969   AITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCG 1019
              +T Y ++K +     W TV     +TS  +T LV GNEYYFRV + N  G
Sbjct: 18729 QVTHYIVEKREADRKTWSTVTPEVKKTSFHVTNLVPGNEYYFRVTAVNEYG 18779



 Score =  233 bits (594), Expect = 8e-61
 Identities = 159/513 (30%), Positives = 252/513 (49%), Gaps = 34/513 (6%)

Query: 545   DPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWS---RGDKAIMEGSGRI--- 598
             + P++ +D + A + +   AG+++R+   I G P PK+ W    +  KA+ +G   I   
Sbjct: 15806 EEPEVFID-IGAQDCLVCKAGSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPED 15864

Query: 599   -RTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVG 657
              + E+  +SS ++I   +R  +G Y I  KN+AG+  A+ +VKV+D P PP    V+++ 
Sbjct: 15865 AQLETAENSSVIIIPECKRSHTGKYSITAKNKAGQKTANCRVKVMDVPGPPKDLKVSDIT 15924

Query: 658   DDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEV 717
                C ++W+ P  DGG  I GY IE++      W ++N D C  TTF    ++    Y  
Sbjct: 15925 RGSCRLSWKMPDDDGGDRIKGYVIEKRTIDGKAWTKVNPD-CGSTTFVVPDLLSEQQYFF 15983

Query: 718   RIFAVNAIGISKPSMPSRPFV---PLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGL 774
             R+ A N  GI  P    +      P+    PP  L +  +T  TV + W+PP + G + +
Sbjct: 15984 RVRAENRFGIGPPVETIQRTTARDPIYPPDPPIKLKIGLITKNTVHLSWKPPKNDGGSPV 16043

Query: 775   DGYVLEYCF----EGT--EDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEP 828
               Y++E C      GT  E W   NK  +++ +FT+  L    +   RVKAVNAAG S+P
Sbjct: 16044 THYIVE-CLAWDPTGTKKEAWRQCNKRDVEELQFTVEDLVEGGEYEFRVKAVNAAGVSKP 16102

Query: 829   KYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTW------KK 882
                  P   +    PP I     LK+      G  VN+V   +G P P LTW      K 
Sbjct: 16103 SATVGPCDCQRPDMPPSI----DLKEFMEVEEGTNVNIVAKIKGVPFPTLTWFKAPPKKP 16158

Query: 883   DGAE---IDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRP 939
             D  E    D +   +   +T T++ I ++ RS +G Y +    +    +  + + ++ RP
Sbjct: 16159 DNKEPVLYDTHVNKLVVDDTCTLV-IPQSRRSDTGLYTITAVNNLGTASKEMRLNVLGRP 16217

Query: 940   GPP-QIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSAT 998
             GPP   +K E V  + + L+W PPKDDG + IT Y I+K +     W  V       + T
Sbjct: 16218 GPPVGPIKFESVSADQMTLSWFPPKDDGGSKITNYVIEKREANRKTWVHVSSEPKECTYT 16277

Query: 999   ITELVIGNEYYFRVFSENMCGLSEDATMTKESA 1031
             I +L+ G+EY FR+ ++N  G+ E      E+A
Sbjct: 16278 IPKLLEGHEYVFRIMAQNKYGIGEPLDSEPETA 16310



 Score =  230 bits (587), Expect = 5e-60
 Identities = 156/568 (27%), Positives = 267/568 (47%), Gaps = 24/568 (4%)

Query: 490   TKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKI 549
             +++G+P++ + R           + +  ++T D G Y       + T  A ++++     
Sbjct: 26511 SRDGVPLKATMRFNTEITAENLTINLKESVTADAGRYEITAANSSGTTKAFINIV----- 26565

Query: 550   ILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIM---EGSGRIRTESYPDS 606
             +LD      T  V+  +     + +  EPP     S+    I+   E S  + TE     
Sbjct: 26566 VLDR-PGPPTGPVVISDITEESVTLKWEPPKYDGGSQVTNYILLKRETSTAVWTEVSATV 26624

Query: 607   STLVIDIAERDDSGVYHINLKNE--------AGEAHASIKVKVVDFPDPPVAPTVTEVGD 658
             +  ++ + +      Y   +K E           A  ++K+     P PP  P VT V  
Sbjct: 26625 ARTMMKVMKLTTGEEYQFRIKAENRFGISDHIDSACVTVKLPYTT-PGPPSTPWVTNVTR 26683

Query: 659   DWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVR 718
             +   + W  P  +GGS ++GY +E K + S  W + N  + + T F+   +  G+ YE R
Sbjct: 26684 ESITVGWHEPVSNGGSAVVGYHLEMKDRNSILWQKANKLVIRTTHFKVTTISAGLIYEFR 26743

Query: 719   IFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYV 778
             ++A NA G+ KPS PS P + +    PP  + +  ++  +V++ W+ P   G + + GY+
Sbjct: 26744 VYAENAAGVGKPSHPSEPVLAIDACEPPRNVRITDISKNSVSLSWQQPAFDGGSKITGYI 26803

Query: 779   LEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGA-SEPKYYSQPILV 837
             +E        W  A+   + +T+F I+GL  +++   RV A NA G+ S P     PI  
Sbjct: 26804 VERRDLPDGRWTKASFTNVTETQFIISGLTQNSQYEFRVFARNAVGSISNPSEVVGPITC 26863

Query: 838   KEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNS 897
              +    P I +P    +    R G +V L     GKP P + W KD  E+  N +    +
Sbjct: 26864 IDSYGGPVIDLPLEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVEN 26923

Query: 898   ETD-TIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPP-QIVKIEDVWGENV 955
              TD   I I+ A+R +SG Y+L+++      +A+I +QI+D+PGPP   ++ + V  E +
Sbjct: 26924 TTDLASILIKDADRLNSGCYELKLRNAMGSASATIRVQILDKPGPPGGPIEFKTVTAEKI 26983

Query: 956   ALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSE 1015
              L W PP DDG A IT Y ++K +   + W  V EH      T T+++ GNEY FRV + 
Sbjct: 26984 TLLWRPPADDGGAKITHYIVEKRETSRVVWSMVSEHLEECIITTTKIIKGNEYIFRVRAV 27043

Query: 1016  NMCGLSEDATMTKESAVIARDGKIYKNP 1043
             N  G+ E     +  +V+A++  +   P
Sbjct: 27044 NKYGIGEP---LESDSVVAKNAFVTPGP 27068



 Score =  230 bits (586), Expect = 7e-60
 Identities = 161/526 (30%), Positives = 248/526 (47%), Gaps = 48/526 (9%)

Query: 545   DPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYP 604
             + P+I LD +     +TV AG K+ L   ++G+P PK  W++ D  I++   RI  E+ P
Sbjct: 13686 EAPEIFLD-VKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADM-ILKQDKRITIENVP 13743

Query: 605   DSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMN 664
               ST+ I  ++R D+G Y I   N  G A A ++V V+D P PP A  +T+V ++ C++ 
Sbjct: 13744 KKSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNVLDKPGPPAAFDITDVTNESCLLT 13803

Query: 665   WEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNA 724
             W PP  DGGS I  Y +ER+   S  W +L+    K+T F+  K+I    Y  R+ A N 
Sbjct: 13804 WNPPRDDGGSKITNYVVERRATDSEVWHKLS-STVKDTNFKATKLIPNKEYIFRVAAENM 13862

Query: 725   IGISKP--SMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYC 782
              G+ +P  + P           PPT L    +T   VT+ W  PD  G + + GY +E  
Sbjct: 13863 YGVGEPVQASPITAKYQFDPPGPPTRLEPSDITKDAVTLTWCEPDDDGGSPITGYWVERL 13922

Query: 783   FEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIE 842
                T+ W+  NK  +  T + + GL    K   RV A N AG  +P   ++PIL+K+ I+
Sbjct: 13923 DPDTDKWVRCNKMPVKDTTYRVKGLTNKKKYRFRVLAENLAGPGKPSKSTEPILIKDPID 13982

Query: 843   PPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKK----DGAEIDKNQINIRNSE 898
             PP       +K                  GK    L W K     GA+I+   I +  + 
Sbjct: 13983 PPWPPGKPTVKDV----------------GKTSVRLNWTKPEHDGGAKIESYVIEMLKTG 14026

Query: 899   TDTIIFIRKAE-----------RSHSGKYDLQVK-VDKFVETASID-------IQIIDRP 939
             TD   ++R AE                +Y  +V+ V+K  E+   +        + +  P
Sbjct: 14027 TDE--WVRVAEGVPTTQHLLPGLMEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPP 14084

Query: 940   GPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATI 999
              PP+ +++ ++      L WT P+ DG + IT Y ++K D +   W TV      T  T+
Sbjct: 14085 SPPRWLEVINITKNTADLKWTVPEKDGGSPITNYIVEKRDVRRKGWQTVDTTVKDTKCTV 14144

Query: 1000  TELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVY 1045
             T L  G+ Y FRV +EN  G S+   +  E +V+A+D      P Y
Sbjct: 14145 TPLTEGSLYVFRVAAENAIGQSDYTEI--EDSVLAKDTFTTPGPPY 14188



 Score =  230 bits (586), Expect = 7e-60
 Identities = 154/553 (27%), Positives = 257/553 (46%), Gaps = 32/553 (5%)

Query: 489   WTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVF--APDAYNVTLPAKVHVIDP 546
             W K+G  ++E+ R+ V     +  L I  A  ED G Y    +  A ++T+P  + V+D 
Sbjct: 25428 WRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSNSAGSITVPITIIVLDR 25487

Query: 547   P----KIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTES 602
             P     I +D +  D+             I IS  PP      +    I+E      T  
Sbjct: 25488 PGPPGPIRIDEVSCDS-------------ITISWNPPEYDGGCQISNYIVEKKETTSTTW 25534

Query: 603   YPDSSTLV---IDIAERDDSGVYHINL-------KNEAGEAHASIKVKVVDFPDPPVAPT 652
             +  S  +    I I        Y   +       K+   E+ A +       P PP  P 
Sbjct: 25535 HIVSQAVARTSIKIVRLTTGSEYQFRVCAENRYGKSSYSESSAVVAEYPFSPPGPPGTPK 25594

Query: 653   VTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEG 712
             V        ++ W+ P  DGGS ++GY +E K++ S  W + N  L  +T  +   + EG
Sbjct: 25595 VVHATKSTMLVTWQVPVNDGGSRVIGYHLEYKERSSILWSKANKILIADTQMKVSGLDEG 25654

Query: 713   VAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAA 772
             + YE R++A N  GI K S    P        PP    V ++T  +V+++W  P + G A
Sbjct: 25655 LMYEYRVYAENIAGIGKCSKSCEPVPARDPCDPPGQPEVTNITRKSVSLKWSKPHYDGGA 25714

Query: 773   GLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAA-GASEPKYY 831
              + GY++E        W+  N   I +T F +T L  D +   RV A NAA   SEP   
Sbjct: 25715 KITGYIVERRELPDGRWLKCNYTNIQETYFEVTELTEDQRYEFRVFARNAADSVSEPSES 25774

Query: 832   SQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKN- 890
             + PI+VK+ +EPP++ +    +   + + GE + +     G+P P ++W KDG EI++  
Sbjct: 25775 TGPIIVKDDVEPPRVMMDVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERA 25834

Query: 891   QINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQ-IVKIED 949
             +  I +++  T++ ++   R  +G+Y L +K      + +++ +++D+PGPP   ++I  
Sbjct: 25835 RTEIISTDNHTLLTVKDCIRRDTGQYVLTLKNVAGTRSVAVNCKVLDKPGPPAGPLEING 25894

Query: 950   VWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYY 1009
             +  E  +L+W  P++DG A I  Y ++K +   + W         TS  +T+L+ GNEY 
Sbjct: 25895 LTAEKCSLSWGRPQEDGGADIDYYIVEKRETSHLAWTICEGELQMTSCKVTKLLKGNEYI 25954

Query: 1010  FRVFSENMCGLSE 1022
             FRV   N  G+ E
Sbjct: 25955 FRVTGVNKYGVGE 25967



 Score =  229 bits (583), Expect = 1e-59
 Identities = 169/620 (27%), Positives = 271/620 (43%), Gaps = 26/620 (4%)

Query: 419   EGKKHILIIEGATKADAAEYSVMTTGGQSSAKL-SVDLKPLKILTPLTDQTVNLGKEICL 477
             EGK++   +    +      S +T   +       +DLK L  L  L  +  N   +I +
Sbjct: 19947 EGKEYTFRVSAENENGEGTPSEITVVARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPI 20006

Query: 478   KCEISENIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTL 537
             K + + ++   W K   P+    R+ V        L++ +    D G Y         T 
Sbjct: 20007 KGKPAPSV--SWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTK 20064

Query: 538   PA--KVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGS 595
                  + V+  P I    +  D  VT  A       + +   PP     S     I+E  
Sbjct: 20065 EGTISIKVVGKPGIPTGPIKFDE-VTAEA-------MTLKWAPPKDDGGSEITNYILEKR 20116

Query: 596   GRIRTE-----SYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVV-----DFP 645
               +  +     S    +T  +          + ++ +N+ G         +V     D P
Sbjct: 20117 DSVNNKWVTCASAVQKTTFRVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVP 20176

Query: 646   DPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFE 705
             D P  P + +V  D   + W  P   GGSPI GY +E K++ S  W R N    +   F+
Sbjct: 20177 DAPPPPNIVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTPIRMRDFK 20236

Query: 706   PKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRP 765
                + EG+ YE R+ A+N  G+ KPS+PS P V L    PP    V ++T  +VT+ W  
Sbjct: 20237 VTGLTEGLEYEFRVMAINLAGVGKPSLPSEPVVALDPIDPPGKPEVINITRNSVTLIWTE 20296

Query: 766   PDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGA 825
             P + G   L GY++E     ++ W+ AN   + +  FT+T L    K   R++A N AGA
Sbjct: 20297 PKYDGGHKLTGYIVEKRDLPSKSWMKANHVNVPECAFTVTDLVEGGKYEFRIRAKNTAGA 20356

Query: 826   -SEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNL-VIPFQGKPRPELTWKKD 883
              S P   ++ I+ K+  E P I +   +K     + G+ + L  I   GKP P+ +W K 
Sbjct: 20357 ISAPSESTETIICKDEYEAPTIVLDPTIKDGLTIKAGDTIVLNAISILGKPLPKSSWSKA 20416

Query: 884   GAEIDKNQI-NIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPP 942
             G +I  + I  I ++ T +++ I+ A R  +G+Y +        +   + + ++D PGPP
Sbjct: 20417 GKDIRPSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFGTKVEHVKVTVLDVPGPP 20476

Query: 943   QIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITEL 1002
               V+I +V  E   LTWTPP +DG + I  Y ++K +   + W  V E         T+L
Sbjct: 20477 GPVEISNVSAEKATLTWTPPLEDGGSPIKSYILEKRETSRLLWTVVSEDIQSCRHVATKL 20536

Query: 1003  VIGNEYYFRVFSENMCGLSE 1022
             + GNEY FRV + N  G  E
Sbjct: 20537 IQGNEYIFRVSAVNHYGKGE 20556



 Score =  228 bits (580), Expect = 3e-59
 Identities = 170/617 (27%), Positives = 288/617 (46%), Gaps = 47/617 (7%)

Query: 453   VDLKPLKILTPLTDQTV-NLGKEICLKCEISENIPG--KWTKNGLPVQESDRLKVVHKGR 509
             V+   +K+     D  +   G+   L+ ++S   P   +W+K+G  ++ + +L++     
Sbjct: 21456 VEAPKIKVDVKFKDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADF 21515

Query: 510   IHKLVIANALTEDEGDYV--------FAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVT 561
                LV  ++   D G Y         FA   +NV       V+D P       +    VT
Sbjct: 21516 STNLVNKDSTRRDSGAYTLTATNPGGFAKHIFNVK------VLDRP----GPPEGPLAVT 21565

Query: 562   VIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIR-----TESYPDSSTLVIDIAER 616
              +   K  L    S  PP     ++ D  I++     R       S    + L +    +
Sbjct: 21566 EVTSEKCVL----SWFPPLDDGGAKIDHYIVQKRETSRLAWTNVASEVQVTKLKVTKLLK 21621

Query: 617   DDSGVYHINLKNEAG-----EAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYD 671
              +  ++ +   N+ G     E+   + V     PDPP  P VT +  D  ++ W  P  D
Sbjct: 21622 GNEYIFRVMAVNKYGVGEPLESEPVLAVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDSD 21681

Query: 672   GGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPS 731
             GGS I+ Y +ER+ K   RW++ N     +  ++   + EG  YE RI A NA GIS PS
Sbjct: 21682 GGSEIINYIVERRDKAGQRWIKCNKKTLTDLRYKVSGLTEGHEYEFRIMAENAAGISAPS 21741

Query: 732   MPSRPFVPLAVT----SPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTE 787
              P+ PF     T     PP    V   + +++++ W  P + G + + GY++E      +
Sbjct: 21742 -PTSPFYKACDTVFKPGPPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIALPEED 21800

Query: 788   DW-IVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKI 846
             +W IV     +  T +TITGL  + +  +R+ A+N+ G  EP         ++ + PP+I
Sbjct: 21801 EWQIVTPPAGLKATSYTITGLTENQEYKIRIYAMNSEGLGEPALVPGTPKAEDRMLPPEI 21860

Query: 847   RIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKD-GAEIDKNQINIRNSETDTIIFI 905
              +   L++    R    + L +P +G+P PE+ W +D G  +DK   +I ++ + T++ +
Sbjct: 21861 ELDADLRKVVTIRACCTLRLFVPIKGRPAPEVKWARDHGESLDK--ASIESTSSYTLLIV 21918

Query: 906   RKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDD 965
                 R  SGKY L V+     ++A ++++++D PGPPQ +K+++V   +V LTW PP  D
Sbjct: 21919 GNVNRFDSGKYILTVENSSGSKSAFVNVRVLDTPGPPQDLKVKEVTKTSVTLTWDPPLLD 21978

Query: 966   GNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGL---SE 1022
             G + I  Y ++K +     + TV  + H+TS  + +L  G  YYFRV +EN  G+   +E
Sbjct: 21979 GGSKIKNYIVEKRESTRKAYSTVATNCHKTSWKVDQLQEGCSYYFRVLAENEYGIGLPAE 22038

Query: 1023  DATMTKESAVIARDGKI 1039
              A   K S      GKI
Sbjct: 22039 TAESVKASERPLPPGKI 22055



 Score =  228 bits (580), Expect = 3e-59
 Identities = 151/547 (27%), Positives = 256/547 (46%), Gaps = 24/547 (4%)

Query: 489   WTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPD--AYNVTLPAKVHVIDP 546
             W K+GLP++ES+ ++         L I NA  E  G Y    D     + +P  V  + P
Sbjct: 27597 WLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGGKYTVILDNAVCRIAVPITVITLGP 27656

Query: 547   PK-----IILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTE 601
             P      I  D + AD+ +       L  ++P          +S   +   + + ++   
Sbjct: 27657 PSKPKGPIRFDEIKADSVI-------LSWDVPEDNGGGEITCYSIEKRETSQTNWKMVCS 27709

Query: 602   SYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVD-----FPDPPVAPTVTEV 656
             S   ++  V ++  +D    + +  +N  G +   +   +V       P PP  P +  V
Sbjct: 27710 SVARTTFKVPNLV-KDAEYQFRVRAENRYGVSQPLVSSIIVAKHQFRIPGPPGKPVIYNV 27768

Query: 657   GDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYE 716
               D   + W+ P YDGGS + G+ +E+K++ S  W ++N        +    ++EG+ Y+
Sbjct: 27769 TSDGMSLTWDAPVYDGGSEVTGFHVEKKERNSILWQKVNTSPISGREYRATGLVEGLDYQ 27828

Query: 717   VRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDG 776
              R++A N+ G+S PS PS+  + ++   PP       VT  T+T++W PP   G + + G
Sbjct: 27829 FRVYAENSAGLSSPSDPSKFTLAVSPVDPPGTPDYIDVTRETITLKWNPPLRDGGSKIVG 27888

Query: 777   YVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGA-SEPKYYSQPI 835
             Y +E   +G E W+  N   + + ++T+TGL    +   R+ A NA G  S P   S  I
Sbjct: 27889 YSIEK-RQGNERWVRCNFTDVSECQYTVTGLSPGDRYEFRIIARNAVGTISPPSQSSGII 27947

Query: 836   LVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKN-QINI 894
             + ++   PP +          I + GE++ +    QG+P P +TW KDG EI+K   + I
Sbjct: 27948 MTRDENVPPIVEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEI 28007

Query: 895   RNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGP-PQIVKIEDVWGE 953
              +    T +F+R A R H G Y ++ K       A I +++ D PG     ++  ++ GE
Sbjct: 28008 TDVLGSTSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQDTPGKVVGPIRFTNITGE 28067

Query: 954   NVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVF 1013
              + L W  P +DG A IT Y I+K +   + W  + +     S T  +L+ GNEY FRV 
Sbjct: 28068 KMTLWWDAPLNDGCAPITHYIIEKRETSRLAWALIEDKCEAQSYTAIKLINGNEYQFRVS 28127

Query: 1014  SENMCGL 1020
             + N  G+
Sbjct: 28128 AVNKFGV 28134



 Score =  227 bits (578), Expect = 6e-59
 Identities = 154/500 (30%), Positives = 249/500 (49%), Gaps = 18/500 (3%)

Query: 530   PDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDK 589
             P   N  + AK  +++ P+I LD +    +V   AG  +++ IP  G PPP   W R D+
Sbjct: 27253 PIEMNEPVQAK-DILEAPEIDLD-VALRTSVIAKAGEDVQVLIPFKGRPPPTVTW-RKDE 27309

Query: 590   AIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHAS-IKVKVVDFPDPP 648
               +    R   E+   SS L I    R+D+G Y + ++N  GE  +S + VKV+D P   
Sbjct: 27310 KNLGSDARYSIENTDSSSLLTIPQVTRNDTGKYILTIENGVGEPKSSTVSVKVLDTPAAC 27369

Query: 649   VAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKK 708
                 V  V      + W+PP  DGGSPI+ Y IE++      W  ++   C  T+F+   
Sbjct: 27370 QKLQVKHVSRGTVTLLWDPPLIDGGSPIINYVIEKRDATKRTWSVVSHK-CSSTSFKLID 27428

Query: 709   MIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDH 768
             + E   +  R+ A N IGI +P   + P     V +P   L++   T T+V + W  PD 
Sbjct: 27429 LSEKTPFFFRVLAENEIGIGEPCETTEPVKAAEVPAPIRDLSMKDSTKTSVILSWTKPDF 27488

Query: 769   IGAAGLDGYVLEYCFEGTEDWIVANKDLIDKT-KFTITGLPTDAKIFVRVKAVNAAGASE 827
              G + +  YV+E   +G + W  A    I KT +  ++ L   + +  RV A N  G S+
Sbjct: 27489 DGGSVITEYVVERKGKGEQTWSHAG---ISKTCEIEVSQLKEQSVLEFRVFAKNEKGLSD 27545

Query: 828   PKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEI 887
             P     PI VKE+I  P++ +          R+G  V+L +P++GKP+P ++W KDG  +
Sbjct: 27546 PVTIG-PITVKELIITPEVDLSDIPGAQVTVRIGHNVHLELPYKGKPKPSISWLKDGLPL 27604

Query: 888   DKNQ-INIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQI-- 944
              +++ +    +E    + I+ A++ H GKY   V +D  V   ++ I +I   GPP    
Sbjct: 27605 KESEFVRFSKTENKITLSIKNAKKEHGGKYT--VILDNAVCRIAVPITVITL-GPPSKPK 27661

Query: 945   --VKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITEL 1002
               ++ +++  ++V L+W  P+D+G   IT Y+I+K +     W  V     RT+  +  L
Sbjct: 27662 GPIRFDEIKADSVILSWDVPEDNGGGEITCYSIEKRETSQTNWKMVCSSVARTTFKVPNL 27721

Query: 1003  VIGNEYYFRVFSENMCGLSE 1022
             V   EY FRV +EN  G+S+
Sbjct: 27722 VKDAEYQFRVRAENRYGVSQ 27741



 Score =  226 bits (576), Expect = 1e-58
 Identities = 163/554 (29%), Positives = 261/554 (47%), Gaps = 33/554 (5%)

Query: 489   WTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYV--FAPDAYNVTLPAKVHVIDP 546
             W K+ +P++++ R+          L I +A  ED G YV      A        V V+D 
Sbjct: 22181 WHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAGEAIETLNVIVLDK 22240

Query: 547   P-----KIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTE 601
             P      + +D + AD+             I +S  PP     S  +  I+E      T 
Sbjct: 22241 PGPPTGPVKMDEVTADS-------------ITLSWGPPKYDGGSSINNYIVEKRDTSTTT 22287

Query: 602   SYPDSSTLVIDI--AERDDSGV---YHINLKNEAGEA-HASIKVKVVDF----PDPPVAP 651
                 S+T+      A R  +G    + I  +N  G++ + + +  V  +    P PP  P
Sbjct: 22288 WQIVSATVARTTIKACRLKTGCEYQFRIAAENRYGKSTYLNSEPTVAQYPFKVPGPPGTP 22347

Query: 652   TVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIE 711
              VT    D   + W  P  DGGS ++GY +ERK++ S  W++LN     +T F+   + E
Sbjct: 22348 VVTLSSRDSMEVQWNEPISDGGSRVIGYHLERKERNSILWVKLNKTPIPQTKFKTTGLEE 22407

Query: 712   GVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGA 771
             GV YE R+ A N +GI KPS  S  +V      PP       VT  +VT++W+ P + G 
Sbjct: 22408 GVEYEFRVSAENIVGIGKPSKVSECYVARDPCDPPGRPEAIIVTRNSVTLQWKKPTYDGG 22467

Query: 772   AGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGA-SEPKY 830
             + + GY++E        W+ A+   I  T F +TGL  D +   RV A NAAG  SEP  
Sbjct: 22468 SKITGYIVEKKELPEGRWMKASFTNIIDTHFEVTGLVEDHRYEFRVIARNAAGVFSEPSE 22527

Query: 831   YSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKN 890
              +  I  ++ ++PP+I +    K T +   GE+  +     GKP P + W K   E+   
Sbjct: 22528 STGAITARDEVDPPRISMDPKYKDTIVVHAGESFKVDADIYGKPIPTIQWIKGDQELSNT 22587

Query: 891   -QINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQ-IVKIE 948
              ++ I++++  T + ++ A R  SG Y L+ K      + +++++++DRPGPP+  V I 
Sbjct: 22588 ARLEIKSTDFATSLSVKDAVRVDSGNYILKAKNVAGERSVTVNVKVLDRPGPPEGPVVIS 22647

Query: 949   DVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEY 1008
              V  E   L W PP  DG + I  Y +++ +   + W  V  +    S  +T+L+ GNEY
Sbjct: 22648 GVTAEKCTLAWKPPLQDGGSDIINYIVERRETSRLVWTVVDANVQTLSCKVTKLLEGNEY 22707

Query: 1009  YFRVFSENMCGLSE 1022
              FR+ + N  G+ E
Sbjct: 22708 TFRIMAVNKYGVGE 22721



 Score =  225 bits (574), Expect = 2e-58
 Identities = 142/476 (29%), Positives = 224/476 (47%), Gaps = 18/476 (3%)

Query: 598   IRTESYPDSSTLVIDIAERDDSGVYHINLKNEAG-----EAHASIKVKVVDFPDPPVAPT 652
             +   S P   T  I         V+ I  +N+ G     ++       +   P  P  PT
Sbjct: 16265 VHVSSEPKECTYTIPKLLEGHEYVFRIMAQNKYGIGEPLDSEPETARNLFSVPGAPDKPT 16324

Query: 653   VTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETT----FEPKK 708
             V+ V  +   +NWE P YDGGSP+ GY++E K   S RW R+N D  K  T    ++   
Sbjct: 16325 VSSVTRNSMTVNWEEPEYDGGSPVTGYWLEMKDTTSKRWKRVNRDPIKAMTLGVSYKVTG 16384

Query: 709   MIEGVAYEVRIFAVNAIGISKPSMPSRPFV---PLAVTSPPTLLTVDSVTDTTVTMRWRP 765
             +IEG  Y+ R++A+NA G+   S+PS P     P+A   PP     D  T ++  + W P
Sbjct: 16385 LIEGSDYQFRVYAINAAGVGPASLPSDPATARDPIAPPGPPFPKVTDW-TKSSADLEWSP 16443

Query: 766   PDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGA 825
             P   G + + GY++EY  EG E+W       +  TK  +TGL   A    RV+AVN AG 
Sbjct: 16444 PLKDGGSKVTGYIVEYKEEGKEEWEKGKDKEVRGTKLVVTGLKEGAFYKFRVRAVNIAGI 16503

Query: 826   SEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGA 885
              EP   +  I +K+ +  P +++   ++   +   G  + ++    GKP P +TW  +  
Sbjct: 16504 GEPGEVTDVIEMKDRLVSPDLQLDASVRDRIVVHAGGVIRIIAYVSGKPPPTVTWNMNER 16563

Query: 886   EIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIV 945
              + + +  I  +   + + I+  +RSH G Y L  K +      +I + ++D PGP    
Sbjct: 16564 TLPQ-EATIETTAISSSMVIKNCQRSHQGVYSLLAKNEAGERKKTIIVDVLDVPGPVGTP 16622

Query: 946   KI-EDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVI 1004
              +  ++  E+  LTW  P+DDG + IT Y I+K +     W  V     R +AT+  L+ 
Sbjct: 16623 FLAHNLTNESCKLTWFSPEDDGGSPITNYVIEKRESDRRAWTPVTYTVTRQNATVQGLIQ 16682

Query: 1005  GNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPL 1060
             G  Y+FR+ +EN  G+      T E+ VI     + + P  ED +  E    T  L
Sbjct: 16683 GKAYFFRIAAENSIGMG-PFVETSEALVIREPITVPERP--EDLEVKEVTKNTVTL 16735



 Score =  223 bits (569), Expect = 6e-58
 Identities = 160/574 (27%), Positives = 265/574 (46%), Gaps = 34/574 (5%)

Query: 488   KWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNV----TLPAKVHV 543
             +W K    +  + RL++        L + +A+  D G+Y+    A NV    ++   V V
Sbjct: 22576 QWIKGDQELSNTARLEIKSTDFATSLSVKDAVRVDSGNYILK--AKNVAGERSVTVNVKV 22633

Query: 544   IDPP-----KIILDGLDADNTVTVIA-----GNKLRLEIPISGEPPPKAMWSRGDKAIME 593
             +D P      +++ G+ A+            G    +   +      + +W+  D  +  
Sbjct: 22634 LDRPGPPEGPVVISGVTAEKCTLAWKPPLQDGGSDIINYIVERRETSRLVWTVVDANVQT 22693

Query: 594   GSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTV 653
              S ++      +  T  I    +   G        E  E+   +       PD P AP V
Sbjct: 22694 LSCKVTKLLEGNEYTFRIMAVNKYGVG--------EPLESEPVVAKNPFVVPDAPKAPEV 22745

Query: 654   TEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGV 713
             T V  D  I+ WE PA DGGS ILGY +E++ K+  RW R +  L  E       +IE  
Sbjct: 22746 TTVTKDSMIVVWERPASDGGSEILGYVLEKRDKEGIRWTRCHKRLIGELRLRVTGLIENH 22805

Query: 714   AYEVRIFAVNAIGISKPSMPS---RPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIG 770
              YE R+ A NA G+S+PS PS   +   P+    PP    V  +T ++V + W  P + G
Sbjct: 22806 DYEFRVSAENAAGLSEPSPPSAYQKACDPIYKPGPPNNPKVIDITRSSVFLSWSKPIYDG 22865

Query: 771   AAGLDGYVLEYCFEGTEDWIVANKDL-IDKTKFTITGLPTDAKIFVRVKAVNAAGASEPK 829
                + GY++E C     +W +      I+KT   +  L    +   R+ A+N AG  E  
Sbjct: 22866 GCEIQGYIVEKCDVSVGEWTMCTPPTGINKTNIEVEKLLEKHEYNFRICAINKAGVGEHA 22925

Query: 830   YYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTW-KKDGAEID 888
                 PI+V+E +E P I +   L++    R G ++ L +P +G+P PE+ W K DG   D
Sbjct: 22926 DVPGPIIVEEKLEAPDIDLDLELRKIINIRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRD 22985

Query: 889   KNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIE 948
                I++ +S T  +  +    R  SGKY L ++     ++A + ++++D P PP  +K+ 
Sbjct: 22986 AAIIDVTSSFTSLV--LDNVNRYDSGKYTLTLENSSGTKSAFVTVRVLDTPSPPVNLKVT 23043

Query: 949   DVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEY 1008
             ++  ++V++TW PP  DG + I  Y ++K +     +  V+ + H+ S  I +L  G  Y
Sbjct: 23044 EITKDSVSITWEPPLLDGGSKIKNYIVEKREATRKSYAAVVTNCHKNSWKIDQLQEGCSY 23103

Query: 1009  YFRVFSENMCGL---SEDATMTKESAVIARDGKI 1039
             YFRV +EN  G+   ++ A   K + V    GKI
Sbjct: 23104 YFRVTAENEYGIGLPAQTADPIKVAEVPQPPGKI 23137



 Score =  222 bits (566), Expect = 1e-57
 Identities = 161/583 (27%), Positives = 256/583 (43%), Gaps = 22/583 (3%)

Query: 455   LKPLKILTPLTDQTVNLGKEICLKCEI--SENIPGKWTKNGLPVQESDRLKVVHKGRIHK 512
             L P KIL P    T+  GK++ ++  +    +   KW K    V  S  L V        
Sbjct: 18897 LLPPKILMP-EQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSI 18955

Query: 513   LVIANALTEDEGDYVFAPDAYNVTLPAKVHVI-----DPPKIILDGLDADNTVTVIAGNK 567
             L+I +   +D G Y    +  + T   K+ V+      PP+   D  D D          
Sbjct: 18956 LIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPGPPQPPFDISDIDADAC-----S 19010

Query: 568   LRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLK 627
             L   IP+         +      +  G       S   +S  V  +    +  ++ +  +
Sbjct: 19011 LSWHIPLEDGGSNITNYIVEKCDVSRGDWVTALASVTKTSCRVGKLIPGQEY-IFRVRAE 19069

Query: 628   NEAGEAHASIKVKVV-----DFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIE 682
             N  G +      K+V       P  P    VT+V  D   + W+ P  DGGSPI+GY IE
Sbjct: 19070 NRFGISEPLTSPKMVAQFPFGVPSEPKNARVTKVNKDCIFVAWDRPDSDGGSPIIGYLIE 19129

Query: 683   RKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAV 742
             RK++ S  W++ N  L + T +    ++EG+ Y  RI+A+N  G S PS P+        
Sbjct: 19130 RKERNSLLWVKANDTLVRSTEYPCAGLVEGLEYSFRIYALNKAGSSPPSKPTEYVTARMP 19189

Query: 743   TSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVAN--KDLIDKT 800
               PP    V  VT +TV++ W  P H G + + GY +E C    + W+  N     I + 
Sbjct: 19190 VDPPGKPEVIDVTKSTVSLIWARPKHDGGSKIIGYFVEACKLPGDKWVRCNTAPHQIPQE 19249

Query: 801   KFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRV 860
             ++T TGL   A+   R  A  A   S P   S P+ +     PP+I +   +K     + 
Sbjct: 19250 EYTATGLEEKAQYQFRAIARTAVNISPPSEPSDPVTILAENVPPRIDLSVAMKSLLTVKA 19309

Query: 861   GEAVNLVIPFQGKPRPELTWKKDGAEIDKNQ-INIRNSETDTIIFIRKAERSHSGKYDLQ 919
             G  V L     GKP P ++WKKDG  +   + I +        + +    R  SG Y + 
Sbjct: 19310 GTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTIT 19369

Query: 920   VKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKAD 979
              +     ++A+I ++++D+PGPP  VKI  ++ +   L+W PP +DG + IT Y + K +
Sbjct: 19370 AENSSGSKSATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYIVDKRE 19429

Query: 980   KKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSE 1022
                  W  V      TS ++ +L+ G+EY FR+ +EN  G+ +
Sbjct: 19430 TSRPNWAQVSATVPITSCSVEKLIEGHEYQFRICAENKYGVGD 19472



 Score =  222 bits (565), Expect = 2e-57
 Identities = 160/535 (29%), Positives = 257/535 (48%), Gaps = 52/535 (9%)

Query: 527   VFAPDAYNVTLPAKV--HVI--DP---PKIILDGLDADNTVTVIAGNKLRLEIPISGEPP 579
             V A +A  V+ P+++  +V+  DP   P I L+  D    + VI G KL + +P    P 
Sbjct: 14360 VRAVNAIGVSEPSEISENVVAKDPDCKPTIDLETHD----IIVIEGEKLSIPVPFRAVPV 14415

Query: 580   PKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKV 639
             P   W +  K + + S R+  ++   S+ L +  + R D+G+Y I L+N+ G A ASI V
Sbjct: 14416 PTVSWHKDGKEV-KASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATASINV 14474

Query: 640   KVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLC 699
             KV+  P P      +++    C + WEPP +DGG+PIL Y +ER++     ++ +     
Sbjct: 14475 KVIGLPGPCKDIKASDITKSSCKLTWEPPEFDGGTPILHYVLERREAGRRTYIPVMSGEN 14534

Query: 700   KETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFV---PLAVTSPPTLLTVDSVTD 756
             K  ++  K +I    Y  R+ AVN +G  +      P +   P     PP  + V + T 
Sbjct: 14535 K-LSWTVKDLIPNGEYFFRVKAVNKVGGGEYIELKNPVIAQDPKQPPDPPVDVEVHNPTA 14593

Query: 757   TTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVR 816
               +T+ W+PP + G + + GY++E   +G E W   N+ L+    +T  GL    +   R
Sbjct: 14594 EAMTITWKPPLYDGGSKIMGYIIEKIAKGEERWKRCNEHLVPILTYTAKGLEEGKEYQFR 14653

Query: 817   VKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRP 876
             V+A NAAG SEP   + P    + I+ PK+ +   L+   ++R G+ + L     G P P
Sbjct: 14654 VRAENAAGISEPSRATPPTKAVDPIDAPKVILRTSLE---VKR-GDEIALDASISGSPYP 14709

Query: 877   ELTWKKD-----GAEIDK------------------------NQINIRNSET-DTIIFIR 906
              +TW KD       EI K                         +++I NS+  ++ + +R
Sbjct: 14710 TITWIKDENVIVPEEIKKRAAPLVRRRKGEVQEEEPFVLPLTQRLSIDNSKKGESQLRVR 14769

Query: 907   KAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDG 966
              + R   G Y ++V+ D  +  A   + ++D PGPP     ED+   +V   W PP DDG
Sbjct: 14770 DSLRPDHGLYMIKVENDHGIAKAPCTVSVLDTPGPPINFVFEDIRKTSVLCKWEPPLDDG 14829

Query: 967   NAAITGYTIQKAD--KKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCG 1019
              + I  YT++K D  K   EW  V         ++T+L+ G EY FRV +EN  G
Sbjct: 14830 GSEIINYTLEKKDKTKPDSEWIVVTSTLRHCKYSVTKLIEGKEYLFRVRAENRFG 14884



 Score =  220 bits (561), Expect = 5e-57
 Identities = 176/654 (26%), Positives = 292/654 (44%), Gaps = 63/654 (9%)

Query: 405   EIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPL 464
             +++ G K  +RIR +         GA  A +     +    +  A       P  +L P 
Sbjct: 20337 DLVEGGKYEFRIRAKNTA------GAISAPSESTETIICKDEYEA-------PTIVLDPT 20383

Query: 465   TDQ--TVNLGKEICLKCE--ISENIP-GKWTKNGLPVQESDRLKVVHKGRIHKLVIANAL 519
                  T+  G  I L     + + +P   W+K G  ++ SD  ++        L I  A 
Sbjct: 20384 IKDGLTIKAGDTIVLNAISILGKPLPKSSWSKAGKDIRPSDITQITSTPTSSMLTIKYAT 20443

Query: 520   TEDEGDY-VFAPDAYNVTLP-AKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGE 577
              +D G+Y + A + +   +   KV V+D P     G      ++ ++  K  L    +  
Sbjct: 20444 RKDAGEYTITATNPFGTKVEHVKVTVLDVP-----GPPGPVEISNVSAEKATL----TWT 20494

Query: 578   PPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLK----NE---- 629
             PP +   S     I+E           ++S L+  +   D     H+  K    NE    
Sbjct: 20495 PPLEDGGSPIKSYILEKR---------ETSRLLWTVVSEDIQSCRHVATKLIQGNEYIFR 20545

Query: 630   --------AGEAHASIKVKVVDF---PDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILG 678
                      GE   S  VK+VD    P PP  P V+ V  +   ++W+ P  DGGS I G
Sbjct: 20546 VSAVNHYGKGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSWKRPVDDGGSEITG 20605

Query: 679   YFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFV 738
             Y +ER++K+S RW+R       +   +   + EG  YE R+ A N  GI  PS  S   +
Sbjct: 20606 YHVERREKKSLRWVRAIKTPVSDLRCKVTGLQEGSTYEFRVSAENRAGIGPPSEASDSVL 20665

Query: 739   PLAVTSPPTLLTVDSVTDTT---VTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIV-ANK 794
                   PP   +   VTDTT    ++ W  P + G   + GYV+E+   G E WI     
Sbjct: 20666 MKDAAYPPGPPSNPHVTDTTKKSASLAWGKPHYDGGLEITGYVVEHQKVGDEAWIKDTTG 20725

Query: 795   DLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQ 854
               +  T+F +  L T  K   R+ A+N AG  EP       +V+  + P    +   L++
Sbjct: 20726 TALRITQFVVPDLQTKEKYNFRISAINDAGVGEPAVIPDVEIVEREMAPD-FELDAELRR 20784

Query: 855   TYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSG 914
             T + R G ++ + +P +G+P PE+TW KD   + KN+ NI N+E+ T++ I +  R  +G
Sbjct: 20785 TLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINL-KNRANIENTESFTLLIIPECNRYDTG 20843

Query: 915   KYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYT 974
             K+ + ++     ++  ++++++D PGP   ++  D+  ++V L W  P  DG + IT Y 
Sbjct: 20844 KFVMTIENPAGKKSGFVNVRVLDTPGPVLNLRPTDITKDSVTLHWDLPLIDGGSRITNYI 20903

Query: 975   IQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTK 1028
             ++K +     + T     H+ +  +T L  G EY+FRV +EN  G+ E    T+
Sbjct: 20904 VEKREATRKSYSTATTKCHKCTYKVTGLSEGCEYFFRVMAENEYGIGEPTETTE 20957



 Score =  218 bits (554), Expect = 3e-56
 Identities = 159/598 (26%), Positives = 266/598 (44%), Gaps = 55/598 (9%)

Query: 459   KILTPLTDQTVNLGKEICLKCEISENIPG----------KWTKNGLPVQESDRLKVVHKG 508
             K++ P  +  V L + + +K   +   P           KWT +G  ++  +   V    
Sbjct: 17504 KLVPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDN 17563

Query: 509   RIHKLVIANALTEDEGDYVFAPD--AYNVTLPAKVHVID---PPKIILDGLDADNTVTVI 563
                 L I N L  D G+Y       A + T+   + V+D   PP   ++ LD        
Sbjct: 17564 FSSVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTVLDVPGPPTGPINILDVTPE---- 17619

Query: 564   AGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIR-----TESYPDSSTLVIDIAERDD 618
                     + IS +PP     S     I+E     +       S    + L I   ++  
Sbjct: 17620 -------HMTISWQPPKDDGGSPVINYIVEKQDTRKDTWGVVSSGSSKTKLKIPHLQKGC 17672

Query: 619   SGVYHINLKNEAG-----EAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGG 673
               V+ +  +N+ G     ++  ++       P PP  P VT++ ++   ++W  P  DGG
Sbjct: 17673 EYVFRVRAENKIGVGPPLDSTPTVAKHKFSPPSPPGKPVVTDITENAATVSWTLPKSDGG 17732

Query: 674   SPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMP 733
             SPI GY++ER++  + +W+R+N     +  F    + EG  YE R+FA N  G+SKPS  
Sbjct: 17733 SPITGYYMERREV-TGKWVRVNKTPIADLKFRVTGLYEGNTYEFRVFAENLAGLSKPSPS 17791

Query: 734   SRPFV---PLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWI 790
             S P     P+    PP    +   +  T  + W  P   G + + GYV+E    GT  W 
Sbjct: 17792 SDPIKACRPIKPPGPPINPKLKDKSRETADLVWTKPLSDGGSPILGYVVECQKPGTAQWN 17851

Query: 791   VANKD-LIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIP 849
               NKD LI +  F + GL    +   R+KA N  G  EP+  ++ ++ K+I+ PP++ + 
Sbjct: 17852 RINKDELIRQCAFRVPGLIEGNEYRFRIKAANIVGEGEPRELAESVIAKDILHPPEVELD 17911

Query: 850   RHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTI------- 902
                +     RVG+ + ++   +G+P P++TW K+G      ++ +R    D I       
Sbjct: 17912 VTCRDVITVRVGQTIRILARVKGRPEPDITWTKEG------KVLVREKRVDLIQDLPRVE 17965

Query: 903   IFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPP 962
             + I++A R+  GKY +  K        S  + ++DRPGP Q +K+ +V  EN  ++W  P
Sbjct: 17966 LQIKEAVRADHGKYIISAKNSSGHAQGSAIVNVLDRPGPCQNLKVTNVTKENCTISWENP 18025

Query: 963   KDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGL 1020
              D+G + IT + ++        W  V     +       L+  NEYYFRV +EN  G+
Sbjct: 18026 LDNGGSEITNFIVEYRKPNQKGWSIVASDVTKRLIK-ANLLANNEYYFRVCAENKVGV 18082



 Score =  214 bits (544), Expect = 5e-55
 Identities = 128/407 (31%), Positives = 204/407 (50%), Gaps = 22/407 (5%)

Query: 636   SIKVKVVD---FPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWM 692
             S KV + D    P PP  P V        +++W PP  +GGSPI GY++E++++ S  W 
Sbjct: 15587 SDKVVIQDPYRLPGPPGKPKVLARTKGSMLVSWTPPLDNGGSPITGYWLEKREEGSPYWS 15646

Query: 693   RLNFDLC-----KETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFV---PLAVTS 744
             R++         K   F   +++EGV Y+ R  A+NA GI  PS PS P V   P+    
Sbjct: 15647 RVSRAPITKVGLKGVEFNVPRLLEGVKYQFRAMAINAAGIGPPSEPSDPEVAGDPIFPPG 15706

Query: 745   PPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKD--LIDKTKF 802
             PP+   V   T +++++ W+PP   G + + GY++E   EGT DW   N+   LI   + 
Sbjct: 15707 PPSCPEVKDKTKSSISLGWKPPAKDGGSPIKGYIVEMQEEGTTDWKRVNEPDKLITTCEC 15766

Query: 803   TITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGE 862
              +  L    K   RVKAVN AG SEP   +  I   +I E P++ I    +   + + G 
Sbjct: 15767 VVPNLKELRKYRFRVKAVNEAGESEPSDTTGEIPATDIQEEPEVFIDIGAQDCLVCKAGS 15826

Query: 863   AVNLVIPFQGKPRPELTWK---------KDGAEIDKNQINIRNSETDTIIFIRKAERSHS 913
              + +    +G+P P+ +W+         KDG         +  +E  ++I I + +RSH+
Sbjct: 15827 QIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECKRSHT 15886

Query: 914   GKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGY 973
             GKY +  K     +TA+  ++++D PGPP+ +K+ D+   +  L+W  P DDG   I GY
Sbjct: 15887 GKYSITAKNKAGQKTANCRVKVMDVPGPPKDLKVSDITRGSCRLSWKMPDDDGGDRIKGY 15946

Query: 974   TIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGL 1020
              I+K       W  V      T+  + +L+   +Y+FRV +EN  G+
Sbjct: 15947 VIEKRTIDGKAWTKVNPDCGSTTFVVPDLLSEQQYFFRVRAENRFGI 15993



 Score =  214 bits (544), Expect = 5e-55
 Identities = 163/595 (27%), Positives = 269/595 (45%), Gaps = 44/595 (7%)

Query: 468   TVNLGKEICLKCEISENIPGK--WTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGD 525
             T+  G ++ L   +      K  WTK    +   +++ + + G+    VI      D G 
Sbjct: 29058 TIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSGK 29117

Query: 526   YVFAPDAYNVT--LPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPP---- 579
             Y       + T  +   V V+D P     G     TV+ +   K  L   +  E      
Sbjct: 29118 YTLTVKNASGTKAVSVMVKVLDSP-----GPCGKLTVSRVTQEKCTLAWSLPQEDGGAEI 29172

Query: 580   -----PKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAG--- 631
                   +   SR +  I+EG     T SY      V+    +++  ++ +   N+ G   
Sbjct: 29173 THYIVERRETSRLNWVIVEGE--CPTLSY------VVTRLIKNNEYIFRVRAVNKYGPGV 29224

Query: 632   --EAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSS 689
               E+   +       P PP  P     G +  I+ W  P  DGG+ I  Y +++++K+S 
Sbjct: 29225 PVESEPIVARNSFTIPSPPGIPEEVGTGKEHIIIQWTKPESDGGNEISNYLVDKREKKSL 29284

Query: 690   RWMRLNFD-LCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFV----PLAVTS 744
             RW R+N D +  +T  +   ++EG  Y+ R+ AVNA G S+PS  S  F+    P     
Sbjct: 29285 RWTRVNKDYVVYDTRLKVTSLMEGCDYQFRVTAVNAAGNSEPSEASN-FISCREPSYTPG 29343

Query: 745   PPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWI-VANKDLIDKTKFT 803
             PP+   V   T  ++++ W  P + G   + GYVLE   + T+ W  V     I  T+FT
Sbjct: 29344 PPSAPRVVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDTDQWYRVHTNATIRNTEFT 29403

Query: 804   ITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEA 863
             +  L    K   RV AVN  G SE       I   E IE P + +   LK+T   R G +
Sbjct: 29404 VPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEIPDLELADDLKKTVTIRAGAS 29463

Query: 864   VNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVD 923
             + L++   G+P P +TW K G ++    I I  +E+ +++ + K  R  +GKY ++ +  
Sbjct: 29464 LRLMVSVSGRPPPVITWSKQGIDLASRAI-IDTTESYSLLIVDKVNRYDAGKYTIEAENQ 29522

Query: 924   KFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSM 983
                ++A++ +++ D PGP   VK+++V  ++V +TW  P  DG A +  Y ++K +    
Sbjct: 29523 SGKKSATVLVKVYDTPGPCPSVKVKEVSRDSVTITWEIPTIDGGAPVNNYIVEKREAAMR 29582

Query: 984   EWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSE-----DATMTKESAVI 1033
              + TV     +T   I+ LV G  YYFRV  EN+ G+ E     DA +  E  ++
Sbjct: 29583 AFKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYGIGEPCETSDAVLVSEVPLV 29637



 Score =  213 bits (543), Expect = 6e-55
 Identities = 156/581 (26%), Positives = 275/581 (47%), Gaps = 32/581 (5%)

Query: 469   VNLGKEICLKCEI-SENIPGK-WTKNGLPVQESD-RLKVVHKGRIHKLVIANALTEDEGD 525
             V+ G+   L+ +I  + IP   W+K+G  ++E+  R+++    +   LV+ + +  D G 
Sbjct: 24719 VHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQ 24778

Query: 526   YVFAPDAYNVT--LPAKVHVIDPP-----KIILDGLDAD------NTVTVIAGNKLRLEI 572
             Y+        T  +P  V V+D P      + + G+ A+      N      G  +   I
Sbjct: 24779 YILKLSNVGGTKSIPITVKVLDRPGPPEGPLKVTGVTAEKCYLAWNPPLQDGGANISHYI 24838

Query: 573   PISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGE 632
              I      +  W++    +   + ++ T+  P +  +   +A       Y I    E+G 
Sbjct: 24839 -IEKRETSRLSWTQVSTEVQALNYKV-TKLLPGNEYIFRVMAVNK----YGIGEPLESGP 24892

Query: 633   AHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWM 692
               A    K    P PP  P V+ +  D  ++ W  P  DGG+ I GY +E++ K+  RW 
Sbjct: 24893 VTACNPYKP---PGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDKEGVRWT 24949

Query: 693   RLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVD 752
             + N     +       + EG +YE R+ A NA G+ +PS PS  +       PP   +  
Sbjct: 24950 KCNKKTLTDLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRACDALYPPGPPSNP 25009

Query: 753   SVTDT---TVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDL-IDKTKFTITGLP 808
              VTDT   +V++ W  P + G A + GYV+E      ++W        +   +FT+T L 
Sbjct: 25010 KVTDTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAADEWTTCTPPTGLQGKQFTVTKLK 25069

Query: 809   TDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVI 868
              + +   R+ A+N+ G  EP      ++ +E IEPP+I +   L++  + R    + L +
Sbjct: 25070 ENTEYNFRICAINSEGVGEPATLPGSVVAQERIEPPEIELDADLRKVVVLRASATLRLFV 25129

Query: 869   PFQGKPRPELTWKK-DGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVE 927
               +G+P PE+ W+K +G   D+ QI + +S   T++ I    R  SG+Y+L ++ +   +
Sbjct: 25130 TIKGRPEPEVKWEKAEGILTDRAQIEVTSS--FTMLVIDNVTRFDSGRYNLTLENNSGSK 25187

Query: 928   TASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFT 987
             TA ++++++D P  P  + I +V  ++V L+W PP  DG A IT Y ++K +     + T
Sbjct: 25188 TAFVNVRVLDSPSAPVNLTIREVKKDSVTLSWEPPLIDGGAKITNYIVEKRETTRKAYAT 25247

Query: 988   VIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTK 1028
             +  +  +T+  I  L  G  YYFRV + N  G+   A  T+
Sbjct: 25248 ITNNCTKTTFRIENLQEGCSYYFRVLASNEYGIGLPAETTE 25288



 Score =  213 bits (542), Expect = 8e-55
 Identities = 117/390 (30%), Positives = 208/390 (53%), Gaps = 6/390 (1%)

Query: 645   PDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTF 704
             P PP  P VT++  +   + W  P  DGGS I GYF+E++ K+S  W ++  +  ++T  
Sbjct: 27066 PGPPGIPEVTKITKNSMTVVWSRPIADGGSDISGYFLEKRDKKSLGWFKVLKETIRDTRQ 27125

Query: 705   EPKKMIEGVAYEVRIFAVNAIG---ISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTM 761
             +   + E   Y+ R+ AVNA G    S+PS   +   P+    PP  + +   T +++T+
Sbjct: 27126 KVTGLTENSDYQYRVCAVNAAGQGPFSEPSEFYKAADPIDPPGPPAKIRIADSTKSSITL 27185

Query: 762   RWRPPDHIGAAGLDGYVLEYCFEGTEDWI-VANKDLIDKTKFTITGLPTDAKIFVRVKAV 820
              W  P + G + + GYV+E      E+W  V+ K  +  T++ ++ L      + RV AV
Sbjct: 27186 GWSKPVYDGGSAVTGYVVEIRQGEEEEWTTVSTKGEVRTTEYVVSNLKPGVNYYFRVSAV 27245

Query: 821   NAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTW 880
             N AG  EP   ++P+  K+I+E P+I +   L+ + I + GE V ++IPF+G+P P +TW
Sbjct: 27246 NCAGQGEPIEMNEPVQAKDILEAPEIDLDVALRTSVIAKAGEDVQVLIPFKGRPPPTVTW 27305

Query: 881   KKDGAEIDKN-QINIRNSETDTIIFIRKAERSHSGKYDLQVKVD-KFVETASIDIQIIDR 938
             +KD   +  + + +I N+++ +++ I +  R+ +GKY L ++      +++++ ++++D 
Sbjct: 27306 RKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKYILTIENGVGEPKSSTVSVKVLDT 27365

Query: 939   PGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSAT 998
             P   Q ++++ V    V L W PP  DG + I  Y I+K D     W  V      TS  
Sbjct: 27366 PAACQKLQVKHVSRGTVTLLWDPPLIDGGSPIINYVIEKRDATKRTWSVVSHKCSSTSFK 27425

Query: 999   ITELVIGNEYYFRVFSENMCGLSEDATMTK 1028
             + +L     ++FRV +EN  G+ E    T+
Sbjct: 27426 LIDLSEKTPFFFRVLAENEIGIGEPCETTE 27455



 Score =  210 bits (535), Expect = 5e-54
 Identities = 144/504 (28%), Positives = 232/504 (46%), Gaps = 21/504 (4%)

Query: 545   DPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYP 604
             +PP + LD +     + ++AG  LR+   ++G P P  +W++ +  +     R+  ++  
Sbjct: 15100 EPPAVELD-VSVKGGIQIMAGKTLRIPAVVTGRPVPTKVWTKEEGEL--DKDRVVIDNVG 15156

Query: 605   DSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMN 664
               S L+I  A R D G Y I   N  G   A+ +V+V D P P +           C++N
Sbjct: 15157 TKSELIIKDALRKDHGRYVITATNSCGSKFAAARVEVFDVPGPVLDLKPVVTNRKMCLLN 15216

Query: 665   WEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNA 724
             W  P  DGGS I G+ IERK  +   W R   +  + +  +   ++EG  Y+ R+ A N 
Sbjct: 15217 WSDPEDDGGSEITGFIIERKDAKMHTW-RQPIE-TERSKCDITGLLEGQEYKFRVIAKNK 15274

Query: 725   IGISKPSM--PSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYC 782
              G   P    P     PL   + P  LT    T +T+T+ W+ P   G + + GY++E  
Sbjct: 15275 FGCGPPVEIGPILAVDPLGPPTSPERLTYTERTKSTITLDWKEPRSNGGSPIQGYIIEKR 15334

Query: 783   FEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIE 842
                  D+   NK L   T F +  L        RVKAVN  G SEP      +++++   
Sbjct: 15335 RHDKPDFERVNKRLCPTTSFLVENLDEHQMYEFRVKAVNEIGESEPS-LPLNVVIQDDEV 15393

Query: 843   PPKIRIPRHLKQTYIR-RVGEAVNLVIPFQGKPRPELTWKKDGAEIDK-------NQINI 894
             PP I++   ++   I+ + GE V++     G P P++ W K+   I+K        +  +
Sbjct: 15394 PPTIKLRLSVRGDTIKVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEV 15453

Query: 895   RNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGEN 954
               SE  T + I KA R   G Y +           ++ +++ DRP PP+ + + D+  E+
Sbjct: 15454 SRSEAKTELSIPKAVREDKGTYTVTASNRLGSVFRNVHVEVYDRPSPPRNLAVTDIKAES 15513

Query: 955   VALTWTPPKDDGNAAITGYTIQKAD--KKSMEWFTVIEHYHRTSATITELVIGNEYYFRV 1012
               LTW  P D+G + IT Y I K D  +K  EW  V          I +L+   +Y FRV
Sbjct: 15514 CYLTWDAPLDNGGSEITHYVIDKRDASRKKAEWEEVTNTAVEKRYGIWKLIPNGQYEFRV 15573

Query: 1013  FSENMCGLSEDATMTKESAVIARD 1036
              + N  G+S++    K   V+ +D
Sbjct: 15574 RAVNKYGISDEC---KSDKVVIQD 15594



 Score =  209 bits (533), Expect = 9e-54
 Identities = 155/595 (26%), Positives = 276/595 (46%), Gaps = 28/595 (4%)

Query: 445   GQSSAKLSVDLKPLKILTPLTDQ-TVNLGKEICLKCEI-SENIPG-KWTKNGLPVQESDR 501
             G  +AK  V+L  + +     D   VN G+   L+ ++  + +P  +W +    ++ES R
Sbjct: 23612 GPITAKDEVELPRISMDPKFRDTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESAR 23671

Query: 502   LKVVHKGRIHKLVIANALTEDEGDYVFAPD--AYNVTLPAKVHVIDPPKIILDGLDADNT 559
              ++ +      L++ +A+  D G Y+      A + + P  V V+D P       +    
Sbjct: 23672 CEIKNTDFKALLIVKDAIRIDGGQYILRASNVAGSKSFPVNVKVLDRP----GPPEGPVQ 23727

Query: 560   VTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIR-----TESYPDSSTLVIDIA 614
             VT +   K  L    +  PP +   S     ++E     R       S   +++L +   
Sbjct: 23728 VTGVTSEKCSL----TWSPPLQDGGSDISHYVVEKRETSRLAWTVVASEVVTNSLKVTKL 23783

Query: 615   ERDDSGVYHINLKNE--AGEAHASIKVKVVD---FPDPPVAPTVTEVGDDWCIMNWEPPA 669
                +  V+ I   N+   GE   S  V + +    P PP +  VT +  D   + W  P 
Sbjct: 23784 LEGNEYVFRIMAVNKYGVGEPLESAPVLMKNPFVLPGPPKSLEVTNIAKDSMTVCWNRPD 23843

Query: 670   YDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISK 729
              DGGS I+GY +E++ +   RW++ N     +       + E   YE R+ A NA G+ +
Sbjct: 23844 SDGGSEIIGYIVEKRDRSGIRWIKCNKRRITDLRLRVTGLTEDHEYEFRVSAENAAGVGE 23903

Query: 730   PSMPS---RPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGT 786
             PS  +   +   P+    PPT   +   T  ++T+ W  P + G + + GYV+E C    
Sbjct: 23904 PSPATVYYKACDPVFKPGPPTNAHIVDTTKNSITLAWGKPIYDGGSEILGYVVEICKADE 23963

Query: 787   EDW-IVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPK 845
             E+W IV  +  +  T+F I+ L    +  +RV A+N  G  E       +  ++ +E P+
Sbjct: 23964 EEWQIVTPQTGLRVTRFEISKLTEHQEYKIRVCALNKVGLGEATSVPGTVKPEDKLEAPE 24023

Query: 846   IRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFI 905
             + +   L++  + R G +  + IPF+G+P PE+TW ++  E   +++ I      T + I
Sbjct: 24024 LDLDSELRKGIVVRAGGSARIHIPFKGRPTPEITWSREEGEFT-DKVQIEKGVNYTQLSI 24082

Query: 906   RKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDD 965
                +R+ +GKY L+++     ++A + ++++D PGPPQ + +++V  ++  L W PP  D
Sbjct: 24083 DNCDRNDAGKYILKLENSSGSKSAFVTVKVLDTPGPPQNLAVKEVRKDSAFLVWEPPIID 24142

Query: 966   GNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGL 1020
             G A +  Y I K +     +  V     +TS  +  L  G  YYFRV +EN  G+
Sbjct: 24143 GGAKVKNYVIDKRESTRKAYANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFGV 24197



 Score =  207 bits (528), Expect = 4e-53
 Identities = 124/404 (30%), Positives = 206/404 (50%), Gaps = 10/404 (2%)

Query: 645   PDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTF 704
             P PP A  V +V      + WEPP  DGG PI  Y IE+K++  +RW++       +  F
Sbjct: 14184 PGPPYALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKERLGTRWVKAGKTAGPDCNF 14243

Query: 705   EPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFV---PLAVTSPPTLLTVDSVTDTTVTM 761
                 +IEG   + ++ A N  G+  PS P+       P +  SPP  L V       + +
Sbjct: 14244 RVTDVIEGTEVQFQVRAENEAGVGHPSEPTEILSIEDPTSPPSPPLDLHVTDAGRKHIAI 14303

Query: 762   RWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTIT-GLPTDAKIFVRVKAV 820
              W+PP+  G + + GY +E C  GTE W+  N   I   KF +  G+  D +  +RV+AV
Sbjct: 14304 AWKPPEKNGGSPIIGYHVEMCPVGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYVLRVRAV 14363

Query: 821   NAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTW 880
             NA G SEP   S+ ++ K+    P I +  H     I   GE +++ +PF+  P P ++W
Sbjct: 14364 NAIGVSEPSEISENVVAKDPDCKPTIDLETH---DIIVIEGEKLSIPVPFRAVPVPTVSW 14420

Query: 881   KKDGAEID-KNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRP 939
              KDG E+   +++ ++N      + + K+ R+ +G Y + ++      TASI++++I  P
Sbjct: 14421 HKDGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATASINVKVIGLP 14480

Query: 940   GPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATI 999
             GP + +K  D+   +  LTW PP+ DG   I  Y +++ +     +  V+   ++ S T+
Sbjct: 14481 GPCKDIKASDITKSSCKLTWEPPEFDGGTPILHYVLERREAGRRTYIPVMSGENKLSWTV 14540

Query: 1000  TELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNP 1043
              +L+   EY+FRV + N  G  E   +  ++ VIA+D K   +P
Sbjct: 14541 KDLIPNGEYFFRVKAVNKVGGGEYIEL--KNPVIAQDPKQPPDP 14582



 Score =  205 bits (522), Expect = 2e-52
 Identities = 140/501 (27%), Positives = 228/501 (45%), Gaps = 20/501 (3%)

Query: 543   VIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTES 602
             ++ PP++ LD +   + +TV  G  +R+   + G P P   W++  K ++      R + 
Sbjct: 17902 ILHPPEVELD-VTCRDVITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREK---RVDL 17957

Query: 603   YPDSSTLVIDIAE--RDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDW 660
               D   + + I E  R D G Y I+ KN +G A  S  V V+D P P     VT V  + 
Sbjct: 17958 IQDLPRVELQIKEAVRADHGKYIISAKNSSGHAQGSAIVNVLDRPGPCQNLKVTNVTKEN 18017

Query: 661   CIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIF 720
             C ++WE P  +GGS I  + +E +K     W  +  D+ K        ++    Y  R+ 
Sbjct: 18018 CTISWENPLDNGGSEITNFIVEYRKPNQKGWSIVASDVTKRLI--KANLLANNEYYFRVC 18075

Query: 721   AVNAIGISKPSMPSRPFV---PLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGY 777
             A N +G+        P +   P+     P  L +     T V ++WR PD+ G +    Y
Sbjct: 18076 AENKVGVGPTIETKTPILAINPIDRPGEPENLHIADKGKTFVYLKWRRPDYDGGSPNLSY 18135

Query: 778   VLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILV 837
              +E   +G++DW   +K  I +T + +     +     RV+  N  G S+    ++ ++V
Sbjct: 18136 HVERRLKGSDDWERVHKGSIKETHYMVDRCVENQIYEFRVQTKNEGGESD-WVKTEEVVV 18194

Query: 838   KEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQ---INI 894
             KE ++ P + +   L      + G+ + L    +GKP PE+ W KD    D  +   + I
Sbjct: 18195 KEDLQKPVLDLK--LSGVLTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKI 18252

Query: 895   RNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGEN 954
                   +   + KA+RS  GKY +          A   + ++D+PGP + +KI DV  + 
Sbjct: 18253 DTRADSSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATVNVLDKPGPVRNLKIVDVSSDR 18312

Query: 955   VALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFS 1014
               + W PP+DDG   I  Y ++K + K M W T          T+T L+ GNEY FRV +
Sbjct: 18313 CTVCWDPPEDDGGCEIQNYILEKCETKRMVWSTYSATVLTPGTTVTRLIEGNEYIFRVRA 18372

Query: 1015  ENMCGLSEDATMTKESAVIAR 1035
             EN  G       T+   VIA+
Sbjct: 18373 ENKIGTGPP---TESKPVIAK 18390



 Score =  204 bits (520), Expect = 3e-52
 Identities = 148/557 (26%), Positives = 258/557 (46%), Gaps = 31/557 (5%)

Query: 489   WTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAK----VHVI 544
             W K+G+ +++   +++        L + +A  +  G  V+  +A N +  AK    V V 
Sbjct: 27992 WFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRG--VYTVEAKNASGSAKAEIKVKVQ 28049

Query: 545   DPPKIILDGLDADNTVTVIAGNKLRL--EIPISGEPPP-------KAMWSRGDKAIMEGS 595
             D P  ++  +   N    I G K+ L  + P++    P       K   SR   A++E  
Sbjct: 28050 DTPGKVVGPIRFTN----ITGEKMTLWWDAPLNDGCAPITHYIIEKRETSRLAWALIED- 28104

Query: 596   GRIRTESYPDSSTLVIDIAERDDSGV--YHINLKNEAGEAHASIKVKVVDFPDPPVAPTV 653
              +   +SY     +  +  +   S V  + +    ++    A I+  V   PD P  P  
Sbjct: 28105 -KCEAQSYTAIKLINGNEYQFRVSAVNKFGVGRPLDSDPVVAQIQYTV---PDAPGIPEP 28160

Query: 654   TEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMR-LNFDLCKETTFEPKKMIEG 712
             + +  +   + W  P  DGGS I  Y +ER++K+S+RW++ ++     ET F+   + EG
Sbjct: 28161 SNITGNSITLTWARPESDGGSEIQQYILERREKKSTRWVKVISKRPISETRFKVTGLTEG 28220

Query: 713   VAYEVRIFAVNAIGISKPSMPSRPFV---PLAVTSPPTLLTVDSVTDTTVTMRWRPPDHI 769
               YE  + A NA G+   S  SR      P+    PPT++ V   + TTV++ W  P   
Sbjct: 28221 NEYEFHVMAENAAGVGPASGISRLIKCREPVNPPGPPTVVKVTDTSKTTVSLEWSKPVFD 28280

Query: 770   GAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPK 829
             G   + GY++E C     DW   N +   KT++T+T L    +   RV A+N AG  +  
Sbjct: 28281 GGMEIIGYIIEMCKADLGDWHKVNAEACVKTRYTVTDLQAGEEYKFRVSAINGAGKGDSC 28340

Query: 830   YYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDK 889
               +  I   + +  P++ I  + KQT++ R G ++ L I +QG+P P   W K  + +  
Sbjct: 28341 EVTGTIKAVDRLTAPELDIDANFKQTHVVRAGASIRLFIAYQGRPTPTAVWSKPDSNLSL 28400

Query: 890   NQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIED 949
              + +I  +++ + + +    R+ +GKY L V+ +   ++ +  ++++D PGPP  +  +D
Sbjct: 28401 -RADIHTTDSFSTLTVENCNRNDAGKYTLTVENNSGSKSITFTVKVLDTPGPPGPITFKD 28459

Query: 950   VWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYY 1009
             V   +  L W  P  DG A I  Y ++K +     W  + E   R    + +L  G  YY
Sbjct: 28460 VTRGSATLMWDAPLLDGGARIHHYVVEKREASRRSWQVISEKCTRQIFKVNDLAEGVPYY 28519

Query: 1010  FRVFSENMCGLSEDATM 1026
             FRV + N  G+ E   M
Sbjct: 28520 FRVSAVNEYGVGEPYEM 28536



 Score =  203 bits (517), Expect = 7e-52
 Identities = 137/482 (28%), Positives = 227/482 (47%), Gaps = 20/482 (4%)

Query: 645   PDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTF 704
             P  P  P V  V  +   + WE P +DGGS I+GY++E+K++ +  W++ N   C E  +
Sbjct: 28841 PSAPTRPEVYHVSANAMSIRWEEPYHDGGSKIIGYWVEKKERNTILWVKENKVPCLECNY 28900

Query: 705   EPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWR 764
             +   ++EG+ Y+ R +A+NA G+SK S  SRP +       P    V  VT +TV++ W 
Sbjct: 28901 KVTGLVEGLEYQFRTYALNAAGVSKASEASRPIMAQNPVDAPGRPEVTDVTRSTVSLIWS 28960

Query: 765   PPDHIGAAGLDGYVLE---YCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVN 821
              P + G + + GY++E       G   W+  N  ++    FT+T L        RV A N
Sbjct: 28961 APAYDGGSKVVGYIIERKPVSEVGDGRWLKCNYTIVSDNFFTVTALSEGDTYEFRVLAKN 29020

Query: 822   AAGA-SEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIR-RVGEAVNLVIPFQGKPRPELT 879
             AAG  S+    + P+  ++   PPK  +   L    +  R G  + L     GKP P++ 
Sbjct: 29021 AAGVISKGSESTGPVTCRDEYAPPKAELDARLHGDLVTIRAGSDLVLDAAVGGKPEPKII 29080

Query: 880   WKKDGAEIDK-NQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDR 938
             W K   E+D   +++++ +       I+  +RS SGKY L VK     +  S+ ++++D 
Sbjct: 29081 WTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSGKYTLTVKNASGTKAVSVMVKVLDS 29140

Query: 939   PGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSAT 998
             PGP   + +  V  E   L W+ P++DG A IT Y +++ +   + W  V       S  
Sbjct: 29141 PGPCGKLTVSRVTQEKCTLAWSLPQEDGGAEITHYIVERRETSRLNWVIVEGECPTLSYV 29200

Query: 999   ITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNP--VYEDFDFSEAPM- 1055
             +T L+  NEY FRV + N  G        +   ++AR+     +P  + E+    +  + 
Sbjct: 29201 VTRLIKNNEYIFRVRAVNKYG---PGVPVESEPIVARNSFTIPSPPGIPEEVGTGKEHII 29257

Query: 1056  --FTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMK-NKVAIVDDPRYRMFSNQGVCTLE 1112
               +T+P  +     G N   N  V    K  + W + NK  +V D R ++ S    C  +
Sbjct: 29258 IQWTKPESD-----GGNEISNYLVDKREKKSLRWTRVNKDYVVYDTRLKVTSLMEGCDYQ 29312

Query: 1113  IR 1114
              R
Sbjct: 29313 FR 29314



 Score =  200 bits (509), Expect = 6e-51
 Identities = 218/906 (24%), Positives = 364/906 (40%), Gaps = 113/906 (12%)

Query: 288   QVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEY 347
             +V +   V F  E+     + KW++N + I  S+KYI   K     L I +  + D + Y
Sbjct: 12650 RVKEQQEVVFNCEVNTEGAKAKWFRNEEAIFDSSKYIILQKDLVYTLRIRDAHLDDQANY 12709

Query: 348   YVTAGDE-----KCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKN 402
              V+  +      K +  L V E  + + + L+D      + V   C+V+  +  +KW KN
Sbjct: 12710 NVSLTNHRGENVKSAANLIVEEEDLRIVEPLKDIETMEKKSVTFWCKVNRLNVTLKWTKN 12769

Query: 403   GEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILT 462
             GEE+    +  YR  V+  KH+L I+     D  EY V     +S A+L +   P + + 
Sbjct: 12770 GEEVPFDNRVSYR--VDKYKHMLTIKDCGFPDEGEYIVTAGQDKSVAELLIIEAPTEFVE 12827

Query: 463   PLTDQTVNLGKEICLKCEIS-ENIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTE 521
              L DQTV    +    C++S E    KW +NG  ++E  + K    G IH+L+I +   +
Sbjct: 12828 HLEDQTVTEFDDAVFSCQLSREKANVKWYRNGREIKEGKKYKFEKDGSIHRLIIKDCRLD 12887

Query: 522   DEGDYVFAPD-----AYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISG 576
             DE +Y    +     A        V +I PP+ IL+   AD  V +   NK ++E+    
Sbjct: 12888 DECEYACGVEDRKSRARLFVEEIPVEIIRPPQDILEAPGAD-VVFLAELNKDKVEV---- 12942

Query: 577   EPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHAS 636
                    W R +  +++G               + DI  RD  G Y    K++  EA A 
Sbjct: 12943 ------QWLRNNMVVVQGDKHQMMSEGKIHRLQICDIKPRDQ-GEYRFIAKDK--EARAK 12993

Query: 637   IKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYF-IERKKKQSSRWMRLN 695
             +++          AP +     D  +        D G P+      +   K  + W + N
Sbjct: 12994 LELAA--------APKIKTADQDLVV--------DVGKPLTMVVPYDAYPKAEAEWFKEN 13037

Query: 696   FDL--------CKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPT 747
               L         ++T+F   +  +G     +I   N  G ++  +  +    + V  P  
Sbjct: 13038 EPLSTKTIDTTAEQTSFRILEAKKGDKGRYKIVLQNKHGKAEGFINLKV---IDVPGPVR 13094

Query: 748   LLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGL 807
              L V    D  V++ W  P   G + + GYV+E      + W++A  D  +  +FT+TGL
Sbjct: 13095 NLEVTETFDGEVSLAWEEPLTDGGSKIIGYVVERRDIKRKTWVLAT-DRAESCEFTVTGL 13153

Query: 808   PTDAKIFV-RVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNL 866
                   ++ RV A N  G  EP     P+  +   + P                G  +N+
Sbjct: 13154 QKGGVEYLFRVSARNRVGTGEPVETDNPVEARSKYDVP----------------GPPLNV 13197

Query: 867   VIPFQGKPRPELTWKKD----GAEIDKNQINIRNSET---DTIIFIRKAERS-------H 912
              I    +    LTW+      GAEI    I +R+  +   DT + +R  + S        
Sbjct: 13198 TITDVNRFGVSLTWEPPEYDGGAEITNYVIELRDKTSIRWDTAMTVRAEDLSATVTDVVE 13257

Query: 913   SGKYDLQVKVDKFV-----ETASIDIQI---IDRPGPPQIVKIEDVWGENVALTWTPPKD 964
               +Y  +V+    +       A+  +++   I+RP PP  +   D    +V L W PP  
Sbjct: 13258 GQEYSFRVRAQNRIGVGKPSAATPFVKVADPIERPSPPVNLTSSDQTQSSVQLKWEPPLK 13317

Query: 965   DGNAAITGYTIQKADKKSMEWFTV-IEHYHRTSATITELVIGNEYYFRVFSENMCGLSED 1023
             DG + I GY I++ ++    W    ++     +  +T L  GN+Y +RV +EN  G+S+ 
Sbjct: 13318 DGGSPILGYIIERCEEGKDNWIRCNMKLVPELTYKVTGLEKGNKYLYRVSAENKAGVSDP 13377

Query: 1024  ATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNA-TLNCSVRGNPK 1082
             + +                P+  D  F E  M      +   +   N  T+     G P+
Sbjct: 13378 SEIL--------------GPLTADDAFVEPTMDLSAFKDGLEVIVPNPITILVPSTGYPR 13423

Query: 1083  PKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLE 1142
             P  TW      +    R +M +      L I      D G Y  K  N + T+  E  ++
Sbjct: 13424 PTATWCFGDKVLETGDRVKMKTLSAYAELVISPSERSDKGIYTLKLENRVKTISGE--ID 13481

Query: 1143  VKVIAQ 1148
             V VIA+
Sbjct: 13482 VNVIAR 13487



 Score =  198 bits (503), Expect = 3e-50
 Identities = 173/674 (25%), Positives = 288/674 (42%), Gaps = 74/674 (10%)

Query: 398   KWFKNGEEIIP-----------GPKSRYRIRVEGKKHILIIEGATKA-------DAAEYS 439
             +W +  E ++P           G + ++R+R E    I     AT         DA +  
Sbjct: 14625 RWKRCNEHLVPILTYTAKGLEEGKEYQFRVRAENAAGISEPSRATPPTKAVDPIDAPKVI 14684

Query: 440   VMTT-----GGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKC---------EISENI 485
             + T+     G + +   S+   P   +T + D+ V + +EI  +          E+ E  
Sbjct: 14685 LRTSLEVKRGDEIALDASISGSPYPTITWIKDENVIVPEEIKKRAAPLVRRRKGEVQEEE 14744

Query: 486   PGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYN--VTLPAKVHV 543
             P       LP+ +   +    KG   +L + ++L  D G Y+   +  +     P  V V
Sbjct: 14745 PFV-----LPLTQRLSIDNSKKGE-SQLRVRDSLRPDHGLYMIKVENDHGIAKAPCTVSV 14798

Query: 544   IDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESY 603
             +D P   ++ +  D   T +             EPP       G   I+  +   + ++ 
Sbjct: 14799 LDTPGPPINFVFEDIRKTSVL---------CKWEPP----LDDGGSEIINYTLEKKDKTK 14845

Query: 604   PDSSTLVIDIAERD-----------DSGVYHINLKNEAGEAHASIKVKVVDF-----PDP 647
             PDS  +V+    R               ++ +  +N  G     +   +V       PD 
Sbjct: 14846 PDSEWIVVTSTLRHCKYSVTKLIEGKEYLFRVRAENRFGPGPPCVSKPLVAKDPFGPPDA 14905

Query: 648   PVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPK 707
             P  P V +V  +  ++ W  P  D GSPILGY++E+++  S+ W R+N  L         
Sbjct: 14906 PDKPIVEDVTSNSMLVKWNEPK-DNGSPILGYWLEKREVNSTHWSRVNKSLLNALKANVD 14964

Query: 708   KMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSP--PTLLTVDSVTDTTVTMRWRP 765
              ++EG+ Y  R+ A NA G  K S PS P       SP  P +  V   + TT+ + W P
Sbjct: 14965 GLLEGLTYVFRVCAENAAGPGKFSPPSDPKTAHDPISPPGPPIPRVTDTSSTTIELEWEP 15024

Query: 766   PDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGA 825
             P   G   + GY ++    GT +W    + +I   ++T+  +   A   +RV AVNAAG 
Sbjct: 15025 PAFNGGGEIVGYFVDKQLVGTNEWSRCTEKMIKVRQYTVKEIREGADYKLRVSAVNAAGE 15084

Query: 826   SEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGA 885
               P   +QP+ V E  EPP + +   +K       G+ + +     G+P P   W K+  
Sbjct: 15085 GPPG-ETQPVTVAEPQEPPAVELDVSVKGGIQIMAGKTLRIPAVVTGRPVPTKVWTKEEG 15143

Query: 886   EIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIV 945
             E+DK+++ I N  T + + I+ A R   G+Y +        + A+  +++ D PGP   +
Sbjct: 15144 ELDKDRVVIDNVGTKSELIIKDALRKDHGRYVITATNSCGSKFAAARVEVFDVPGPVLDL 15203

Query: 946   KIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIG 1005
             K      +   L W+ P+DDG + ITG+ I++ D K   W   IE   R+   IT L+ G
Sbjct: 15204 KPVVTNRKMCLLNWSDPEDDGGSEITGFIIERKDAKMHTWRQPIE-TERSKCDITGLLEG 15262

Query: 1006  NEYYFRVFSENMCG 1019
              EY FRV ++N  G
Sbjct: 15263 QEYKFRVIAKNKFG 15276



 Score =  192 bits (487), Expect = 2e-48
 Identities = 179/703 (25%), Positives = 312/703 (44%), Gaps = 63/703 (8%)

Query: 369   VTKQLEDTTAYCGERVELECE-VSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILII 427
             + K+++D T   GE  +L C+ V     ++KW++ G+E+I   K  Y++  +G+ H L +
Sbjct: 30535 IRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRK--YKMSSDGRTHTLTV 30592

Query: 428   EGATKADAAEYSVMTTGG----QSSAKLSVDLKP-LKILTPLTDQTVN-LGKEICLKCE- 480
                 + D   Y+ + T      ++S+KL +   P      PL ++    +G  + L    
Sbjct: 30593 MTEEQEDEGVYTCIATNEVGEVETSSKLLLQATPQFHPGYPLKEKYYGAVGSTLRLHVMY 30652

Query: 481   ISENIPGK-WTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPA 539
             I   +P   W      +Q S+ + + +      LV+ N   +           Y V L  
Sbjct: 30653 IGRPVPAMTWFHGQKLLQNSENITIENTEHYTHLVMKNVQRKTHAG------KYKVQLSN 30706

Query: 540   KVHVIDPPKIILDGLDADN----TVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIME-- 593
                 +D    ILD    D     T  ++    L+    IS +PP     S     ++E  
Sbjct: 30707 VFGTVDA---ILDVEIQDKPDKPTGPIVIEALLKNSAVISWKPPADDGGSWITNYVVEKC 30763

Query: 594   -----GSGRIRTESYPDSSTLVIDIAERDDSGVY-HINLKNEAG-----EAHASIKVKV- 641
                     ++ + +   ++  ++++ E  ++G Y  ++ +N  G     E  + + +K  
Sbjct: 30764 EAKEGAEWQLVSSAISVTTCRIVNLTE--NAGYYFRVSAQNTFGISDPLEVSSVVIIKSP 30821

Query: 642   VDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKE 701
              + P  P  PT+T V  D C++ W+PPA DGG+ I  Y++E+++K+ ++W+ +  +  +E
Sbjct: 30822 FEKPGAPGKPTITAVTKDSCVVAWKPPASDGGAKIRNYYLEKREKKQNKWISVTTEEIRE 30881

Query: 702   TTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTM 761
             T F  K +IEG+ YE R+   N  G S+ S  S P  P +          + + +  V  
Sbjct: 30882 TVFSVKNLIEGLEYEFRVKCENLGGESEWSEISEPITPKSDVPIQAPHFKEELRNLNVRY 30941

Query: 762   RWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTK-----FTITGLPTDAKIFVR 816
             +          G    ++++  +G E      K  I + K       I  +  D     +
Sbjct: 30942 QSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQLIIASVTDDDATVYQ 31001

Query: 817   VKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRV--GEAVNLVIPFQGKP 874
             V+A N  G+             E+  P KI +P+ L+         GE V++ IPF GKP
Sbjct: 31002 VRATNQGGSVSGT------ASLEVEVPAKIHLPKTLEGMGAVHALRGEVVSIKIPFSGKP 31055

Query: 875   RPELTWKKDGAEIDKN---QINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASI 931
              P +TW+K    ID N   Q+ +  S T +++F    ER  +G Y +  K    ++  ++
Sbjct: 31056 DPVITWQKGQDLIDNNGHYQVIVTRSFT-SLVFPNGVERKDAGFYVVCAKNRFGIDQKTV 31114

Query: 932   DIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEH 991
             ++ + D P PP+ VK+ DV  ++V LTWT P  DG + IT Y ++K    +  W  V   
Sbjct: 31115 ELDVADVPDPPRGVKVSDVSRDSVNLTWTEPASDGGSKITNYIVEKCATTAERWLRV-GQ 31173

Query: 992   YHRTSATITELVIGNEYYFRVFSENMCGLSE-----DATMTKE 1029
                T  T+  L     Y FRV +EN  GLS+     + T+TKE
Sbjct: 31174 ARETRYTVINLFGKTSYQFRVIAENKFGLSKPSEPSEPTITKE 31216



 Score =  182 bits (462), Expect = 2e-45
 Identities = 204/892 (22%), Positives = 360/892 (40%), Gaps = 91/892 (10%)

Query: 295  VRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDE 354
            + F V +    +  KW KNG EI+ + K     K     L I N    D ++Y   AG  
Sbjct: 2986 ITFEVTVNYEGISYKWLKNGVEIKSTDKCQMRTKKLTHSLNIRNVHFGDAADYTFVAGKA 3045

Query: 355  KCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRY 414
              +  L+V    I   K ++D      +R   ECEVSE D  V+W K+ +E+      R 
Sbjct: 3046 TSTATLYVEARHIEFRKHIKDIKVLEKKRAMFECEVSEPDITVQWMKDDQEL--QITDRI 3103

Query: 415  RIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKE 474
            +I+ E   H L+I     +DA +Y+V+  G  S+AKL V+ + ++I +   +  V   + 
Sbjct: 3104 KIQKEKYVHRLLIPSTRMSDAGKYTVVAGGNVSTAKLFVEGRDVRIRSIKKEVQVIEKQR 3163

Query: 475  ICLKCEISE-NIPGKWTKNGLPV--QESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPD 531
              ++ E++E ++   W K+G+ +  Q  +R K V + RIH++ I+     D G+Y F   
Sbjct: 3164 AVVEFEVNEDDVDAHWYKDGIEINFQVQERHKYVVERRIHRMFISETRQSDAGEYTFVAG 3223

Query: 532  AYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAI 591
                ++   V+  +PP++    L     VTV +G   R    ISG P PK  W + ++ +
Sbjct: 3224 RNRSSVTLYVNAPEPPQV----LQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLL 3279

Query: 592  MEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAG----EAHASIKVKVVDFPD- 646
              G  + +        TL++  A  +D+ VY    KN+ G     A  S++V  V  PD 
Sbjct: 3280 STGF-KCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQ 3338

Query: 647  --PPVAPTVTEVGDDWCIMNWEPPAY----DGGSPILGYFIERKKKQSSRWMRLNFDLCK 700
              P   P +     D      +P  +     G    + ++ + KK + SR+ R+      
Sbjct: 3339 EMPVYPPAIITPLQDTVTSEGQPARFQCRVSGTDLKVSWYSKDKKIKPSRFFRM------ 3392

Query: 701  ETTFEPKKMIE-GVAY-----EVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSV 754
             T FE    +E   AY          A NA+G    +        L++ +P ++L     
Sbjct: 3393 -TQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSST------ANLSLEAPESILHERIE 3445

Query: 755  TDTTVTMRWRPPDHIGAAGLD---GYVLEYCFEGTE------DWIVANKDLIDKTKFTIT 805
             +  + M+  P        L+   G++ ++  E          W  A +++ +  K +I 
Sbjct: 3446 QEIEMEMKAAPVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIR 3505

Query: 806  GLPTDAKIFVRVKAVNAAGASEPKYYSQ--------PILVKEIIEPPKIRIPRHLKQTYI 857
                 + + +    V   G    K  ++         + V E   P  +  P+ L     
Sbjct: 3506 SSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVTEAYPPTFLSRPKSLTTF-- 3563

Query: 858  RRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKN-QINIRNSETDTIIFIRKAERSHSGKY 916
              VG+A   +    G P  E  W+KDGA +  +    I ++E   I+ +        G Y
Sbjct: 3564 --VGKAAKFICTVTGTPVIETIWQKDGAALSPSPNWRISDAENKHILELSNLTIQDRGVY 3621

Query: 917  DLQVKVDKFVETASIDIQIIDRPG-PPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTI 975
              +       +    ++ IID+P    ++  ++    + V L     +D           
Sbjct: 3622 SCKASNKFGADICQAELIIIDKPHFIKELEPVQSAINKKVHLECQVDED----------- 3670

Query: 976  QKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESA--VI 1033
                K ++ W          S    +L  G +Y    F + +  L       K+S   V 
Sbjct: 3671 ---RKVTVTW----------SKDGQKLPPGKDYKI-CFEDKIATLEIPLAKLKDSGTYVC 3716

Query: 1034 ARDGKIYKNPVYEDFDFSEAPMFTQPLVNTY-AIAGYNATLNCSVRGNPKPKITWMKNKV 1092
                +   +         E P F + +  +Y  + G +A L+C ++G+P  ++TW KN  
Sbjct: 3717 TASNEAGSSSCSATVTVREPPSFVKKVDPSYLMLPGESARLHCKLKGSPVIQVTWFKNNK 3776

Query: 1093 AIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVK 1144
             + +    RM+       L+I      D G+Y C+AVND+G+     ++ +K
Sbjct: 3777 ELSESNTVRMYFVNSEAILDITDVKVEDSGSYSCEAVNDVGSDSCSTEIVIK 3828



 Score =  181 bits (460), Expect = 3e-45
 Identities = 166/686 (24%), Positives = 284/686 (41%), Gaps = 75/686 (10%)

Query: 375   DTTAYCGERV-ELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKA 433
             D    CGE V E + EV+  +   KW+             YR++   +      +GA+K 
Sbjct: 13632 DKWVACGEPVAETKMEVTGLEEG-KWYA------------YRVKALNR------QGASKP 13672

Query: 434   DAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCEISENIPGK--WTK 491
                   +     Q + ++ +D+K L  LT      V  G +I L   ++     K  WTK
Sbjct: 13673 SRPTEEIQAVDTQEAPEIFLDVKLLAGLT------VKAGTKIELPATVTGKPEPKITWTK 13726

Query: 492   NGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNV----TLPAKVHVIDP- 546
               + +++  R+ + +  +   + I ++   D G Y+   +A NV    T   +V+V+D  
Sbjct: 13727 ADMILKQDKRITIENVPKKSTVTIVDSKRSDTGTYII--EAVNVCGRATAVVEVNVLDKP 13784

Query: 547   -PKIILDGLDADNTVTVIAGNKLR-------LEIPISGEPPPKAMWSRGDKAIMEGSGRI 598
              P    D  D  N   ++  N  R           +        +W +    + + + + 
Sbjct: 13785 GPPAAFDITDVTNESCLLTWNPPRDDGGSKITNYVVERRATDSEVWHKLSSTVKDTNFK- 13843

Query: 599   RTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGD 658
              T+  P+   +    AE     +Y +    +A    A  +    D P PP     +++  
Sbjct: 13844 ATKLIPNKEYIFRVAAE----NMYGVGEPVQASPITAKYQ---FDPPGPPTRLEPSDITK 13896

Query: 659   DWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVR 718
             D   + W  P  DGGSPI GY++ER    + +W+R N    K+TT+  K +     Y  R
Sbjct: 13897 DAVTLTWCEPDDDGGSPITGYWVERLDPDTDKWVRCNKMPVKDTTYRVKGLTNKKKYRFR 13956

Query: 719   IFAVNAIGISKPSMPSRPFV---PLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLD 775
             + A N  G  KPS  + P +   P+    PP   TV  V  T+V + W  P+H G A ++
Sbjct: 13957 VLAENLAGPGKPSKSTEPILIKDPIDPPWPPGKPTVKDVGKTSVRLNWTKPEHDGGAKIE 14016

Query: 776   GYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPI 835
              YV+E    GT++W+   +  +  T+  + GL    +   RV+AVN AG SEP   S P+
Sbjct: 14017 SYVIEMLKTGTDEWVRVAEG-VPTTQHLLPGLMEGQEYSFRVRAVNKAGESEPSEPSDPV 14075

Query: 836   LVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRP------------ELTWKKD 883
             L +E + PP    PR L+   I +    +   +P +    P               W+  
Sbjct: 14076 LCREKLYPPS--PPRWLEVINITKNTADLKWTVPEKDGGSPITNYIVEKRDVRRKGWQTV 14133

Query: 884   GAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQ 943
                +   +  +      ++   R A  +  G+ D        +E + +       PGPP 
Sbjct: 14134 DTTVKDTKCTVTPLTEGSLYVFRVAAENAIGQSDYTE-----IEDSVLAKDTFTTPGPPY 14188

Query: 944   IVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHY-HRTSATITEL 1002
              + + DV   +V L W PPK+DG   I  Y I+K ++    W    +      +  +T++
Sbjct: 14189 ALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKERLGTRWVKAGKTAGPDCNFRVTDV 14248

Query: 1003  VIGNEYYFRVFSENMCGLSEDATMTK 1028
             + G E  F+V +EN  G+   +  T+
Sbjct: 14249 IEGTEVQFQVRAENEAGVGHPSEPTE 14274



 Score =  163 bits (413), Expect = 8e-40
 Identities = 125/502 (24%), Positives = 212/502 (42%), Gaps = 72/502 (14%)

Query: 64   VETPPGEEQAKQNANSQLSILFIEKPQGGTVKVGEDITFIAKVKAEDLLRKPTIKWFKGK 123
            ++  P    A + A     + F+ +PQ   V      TFIAKV  + +   P +KW KGK
Sbjct: 8435 IKDKPAVAPATKKAAVDGRLFFVSEPQSIRVVEKTTATFIAKVGGDPI---PNVKWTKGK 8491

Query: 124  WMDLASKAGKHLQLKETFERHSRVYTFEMQIIKAKDNFAGNYRCEVTYKDKFDSCSFDLE 183
            W  L       +        H +    +++I       +G YRC    +      + +L+
Sbjct: 8492 WRQLNQGGRVFI--------HQKGDEAKLEIRDTTKTDSGLYRCVAFNEHGEIESNVNLQ 8543

Query: 184  VHESTGTTPNIDIRSAFKRSGEGQEDAGELDFSGLLKRREV--KQQEEEPQVDVWELLKN 241
            V E                    +++  E D   +LK+  +  K   EE ++D+ ELLKN
Sbjct: 8544 VDERK------------------KQEKIEGDLRAMLKKTPILKKGAGEEEEIDIMELLKN 8585

Query: 242  AKPSEYEKIAFQYGITDLRGMLK-------------------RLKRMRREEKKSAAFAKI 282
              P EYEK A  YGITD RG+L+                    ++R  R+EK+       
Sbjct: 8586 VDPKEYEKYARMYGITDFRGLLQAFELLKQSQEEETHRLEIEEIERSERDEKEFEELVSF 8645

Query: 283  L-------DPAYQV----------DKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIF 325
            +       +P   +          D        +++  P++++ WYK  +++ PS K+  
Sbjct: 8646 IQQRLSQTEPVTLIKDIENQTVLKDNDAVFEIDIKINYPEIKLSWYKGTEKLEPSDKFEI 8705

Query: 326  EHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVE 385
               G +  L + NCQ+ D   Y +  G    S +L V EP     + L+D T   G+   
Sbjct: 8706 SIDGDRHTLRVKNCQLKDQGNYRLVCGPHIASAKLTVIEP--AWERHLQDVTLKEGQTCT 8763

Query: 386  LECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGG 445
            + C+ S  +   +WF+NG   I  P+ R++  VE K H L I      D  +Y+      
Sbjct: 8764 MTCQFSVPNVKSEWFRNGR--ILKPQGRHKTEVEHKVHKLTIADVRAEDQGQYTCKYEDL 8821

Query: 446  QSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCEIS-ENIPGKWTKNGLPVQESDRLKV 504
            ++SA+L ++ +P++    + +  V+  +    +CE+S ++    W K    + ES +   
Sbjct: 8822 ETSAELRIEAEPIQFTKRIQNIVVSEHQSATFECEVSFDDAIVTWYKGPTELTESQKYNF 8881

Query: 505  VHKGRIHKLVIANALTEDEGDY 526
             + GR H + I N   +DEG Y
Sbjct: 8882 RNDGRCHYMTIHNVTPDDEGVY 8903



 Score =  162 bits (411), Expect = 1e-39
 Identities = 110/364 (30%), Positives = 175/364 (48%), Gaps = 16/364 (4%)

Query: 289   VDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYY 348
             V  G    F  EL+   + V+WY  G+++ PS K +   +G    L + + ++ D  E  
Sbjct: 12207 VTAGETATFDCELSYEDIPVEWYLKGKKLEPSDKVVPRSEGKVHTLTLRDVKLEDAGEVQ 12266

Query: 349   VTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIP 408
             +TA D K    LFV+EPP+  TK LED T   G    LECEVS ++A VKWFKNG EI+ 
Sbjct: 12267 LTAKDFKTHANLFVKEPPVEFTKPLEDQTVEEGATAVLECEVSRENAKVKWFKNGTEILK 12326

Query: 409   GPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQT 468
               K  Y I  +G+   L+I   T  D   Y+      ++S  L+V    ++ L PLTD  
Sbjct: 12327 SKK--YEIVADGRVRKLVIHDCTPEDIKTYTCDAKDFKTSCNLNVVPPHVEFLRPLTDLQ 12384

Query: 469   VNLGKEICLKCEIS-ENIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYV 527
             V   +    +CE+S EN   KW K+G  +++  +  ++ KG +  LVI   L +DE +Y 
Sbjct: 12385 VREKEMARFECELSRENAKVKWFKDGAEIKKGKKYDIISKGAVRILVINKCLLDDEAEY- 12443

Query: 528   FAPDAYNVTLPAKVHVIDPPKII---LDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMW 584
              + +         + V++   +    L  ++   T T+    KL  E+    +P  + +W
Sbjct: 12444 -SCEVRTARTSGMLTVLEEEAVFTKNLANIEVSETDTI----KLVCEV---SKPGAEVIW 12495

Query: 585   SRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDF 644
              +GD+ I+E +GR    +      LVI  A  +D+G Y+  L +   +    +     +F
Sbjct: 12496 YKGDEEIIE-TGRYEILTEGRKRILVIQNAHLEDAGNYNCRLPSSRTDGKVKVHELAAEF 12554

Query: 645   PDPP 648
                P
Sbjct: 12555 ISKP 12558



 Score =  157 bits (398), Expect = 4e-38
 Identities = 105/308 (34%), Positives = 159/308 (51%), Gaps = 19/308 (6%)

Query: 544   IDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESY 603
             +DPP+I +D    D T+ V AG   +++  I G+P P   W +GD+ +   + R+  +S 
Sbjct: 22538 VDPPRISMDPKYKD-TIVVHAGESFKVDADIYGKPIPTIQWIKGDQEL-SNTARLEIKST 22595

Query: 604   PDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTV-TEVGDDWCI 662
               +++L +  A R DSG Y +  KN AGE   ++ VKV+D P PP  P V + V  + C 
Sbjct: 22596 DFATSLSVKDAVRVDSGNYILKAKNVAGERSVTVNVKVLDRPGPPEGPVVISGVTAEKCT 22655

Query: 663   MNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDL----CKETTFEPKKMIEGVAYEVR 718
             + W+PP  DGGS I+ Y +ER++     W  ++ ++    CK T     K++EG  Y  R
Sbjct: 22656 LAWKPPLQDGGSDIINYIVERRETSRLVWTVVDANVQTLSCKVT-----KLLEGNEYTFR 22710

Query: 719   IFAVNAIGISKPSMPSRPFV---PLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLD 775
             I AVN  G+ +P + S P V   P  V   P    V +VT  ++ + W  P   G + + 
Sbjct: 22711 IMAVNKYGVGEP-LESEPVVAKNPFVVPDAPKAPEVTTVTKDSMIVVWERPASDGGSEIL 22769

Query: 776   GYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPI 835
             GYVLE   +    W   +K LI + +  +TGL  +     RV A NAAG SEP   S P 
Sbjct: 22770 GYVLEKRDKEGIRWTRCHKRLIGELRLRVTGLIENHDYEFRVSAENAAGLSEP---SPPS 22826

Query: 836   LVKEIIEP 843
               ++  +P
Sbjct: 22827 AYQKACDP 22834



 Score =  157 bits (398), Expect = 4e-38
 Identities = 101/319 (31%), Positives = 164/319 (51%), Gaps = 7/319 (2%)

Query: 531   DAYNVTLPAKV-HVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDK 589
             D   + LP  +   ++PP+I +    + +TV V AG+ L+++IPISG+P PK   SR D 
Sbjct: 26457 DPRELLLPVLIKEQLEPPEIDMKNFPS-HTVYVRAGSNLKVDIPISGKPLPKVTLSR-DG 26514

Query: 590   AIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPV 649
               ++ + R  TE   ++ T+ +  +   D+G Y I   N +G   A I + V+D P PP 
Sbjct: 26515 VPLKATMRFNTEITAENLTINLKESVTADAGRYEITAANSSGTTKAFINIVVLDRPGPPT 26574

Query: 650   APTV-TEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKK 708
              P V +++ ++   + WEPP YDGGS +  Y + +++  ++ W  ++  + + T  +  K
Sbjct: 26575 GPVVISDITEESVTLKWEPPKYDGGSQVTNYILLKRETSTAVWTEVSATVAR-TMMKVMK 26633

Query: 709   MIEGVAYEVRIFAVNAIGISK--PSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPP 766
             +  G  Y+ RI A N  GIS    S      +P     PP+   V +VT  ++T+ W  P
Sbjct: 26634 LTTGEEYQFRIKAENRFGISDHIDSACVTVKLPYTTPGPPSTPWVTNVTRESITVGWHEP 26693

Query: 767   DHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGAS 826
                G + + GY LE     +  W  ANK +I  T F +T +        RV A NAAG  
Sbjct: 26694 VSNGGSAVVGYHLEMKDRNSILWQKANKLVIRTTHFKVTTISAGLIYEFRVYAENAAGVG 26753

Query: 827   EPKYYSQPILVKEIIEPPK 845
             +P + S+P+L  +  EPP+
Sbjct: 26754 KPSHPSEPVLAIDACEPPR 26772



 Score =  157 bits (397), Expect = 5e-38
 Identities = 212/890 (23%), Positives = 342/890 (38%), Gaps = 93/890 (10%)

Query: 292   GGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTA 351
             G  V F+ EL   K+EV+W +N   +    K+    +G    L I + +  D  EY   A
Sbjct: 12926 GADVVFLAELNKDKVEVQWLRNNMVVVQGDKHQMMSEGKIHRLQICDIKPRDQGEYRFIA 12985

Query: 352   GDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSE-DDANVKWFKNGEEIIPGP 410
              D++   +L +   P + T   +D     G+ + +         A  +WFK  E     P
Sbjct: 12986 KDKEARAKLELAAAPKIKTAD-QDLVVDVGKPLTMVVPYDAYPKAEAEWFKENE-----P 13039

Query: 411   KSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLT--DQT 468
              S   I    ++    I  A K D   Y ++       A+  ++LK + +  P+   + T
Sbjct: 13040 LSTKTIDTTAEQTSFRILEAKKGDKGRYKIVLQNKHGKAEGFINLKVIDVPGPVRNLEVT 13099

Query: 469   VNLGKEICLKCEISENIPGKWTKN-GLPVQESD---RLKVVHKGRIHKLVIA-NALTEDE 523
                  E+ L  E  E +    +K  G  V+  D   +  V+   R          L +  
Sbjct: 13100 ETFDGEVSLAWE--EPLTDGGSKIIGYVVERRDIKRKTWVLATDRAESCEFTVTGLQKGG 13157

Query: 524   GDYVFAPDAYNVTLPAKVHVIDPP-----KIILDGLDADNTVTVIAGNKLRLEIPISGEP 578
              +Y+F   A N     +    D P     K  + G   + T+T +     R  + ++ EP
Sbjct: 13158 VEYLFRVSARNRVGTGEPVETDNPVEARSKYDVPGPPLNVTITDVN----RFGVSLTWEP 13213

Query: 579   PPKAMWSRGDKAIMEGSGRIR-------TESYPDSSTLVIDIAERDDSGVYHINLKNEAG 631
             P     +     ++E   +         T    D S  V D+ E  +   + +  +N  G
Sbjct: 13214 PEYDGGAEITNYVIELRDKTSIRWDTAMTVRAEDLSATVTDVVEGQEYS-FRVRAQNRIG 13272

Query: 632   EAHASIK---VKVVD---FPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKK 685
                 S     VKV D    P PPV  T ++       + WEPP  DGGSPILGY IER +
Sbjct: 13273 VGKPSAATPFVKVADPIERPSPPVNLTSSDQTQSSVQLKWEPPLKDGGSPILGYIIERCE 13332

Query: 686   KQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGIS----------------K 729
             +    W+R N  L  E T++   + +G  Y  R+ A N  G+S                +
Sbjct: 13333 EGKDNWIRCNMKLVPELTYKVTGLEKGNKYLYRVSAENKAGVSDPSEILGPLTADDAFVE 13392

Query: 730   PSMPSRPF---VPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGT 786
             P+M    F   + + V +P T+L V S      T  W   D +   G    V        
Sbjct: 13393 PTMDLSAFKDGLEVIVPNPITIL-VPSTGYPRPTATWCFGDKVLETG--DRVKMKTLSAY 13449

Query: 787   EDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKI 846
              + +++  +  DK  +T+       K+  RVK ++  G  +    ++P   KE+      
Sbjct: 13450 AELVISPSERSDKGIYTL-------KLENRVKTIS--GEIDVNVIARPSAPKELKFGDIT 13500

Query: 847   RIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIR 906
             +   HL        G +       + +     TW K    +   +  + +         +
Sbjct: 13501 KDSVHLTWEPPDDDGGSPLTGYVVEKREVSRKTWTKVMDFVTDLEFTVPDLVQGKEYLFK 13560

Query: 907   KAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDG 966
                R+  G  +    VD+ V  ++        P PP+ VK  D    ++ LTW PPK+DG
Sbjct: 13561 VCARNKCGPGE-PAYVDEPVNMSTPATV----PDPPENVKWRDRTANSIFLTWDPPKNDG 13615

Query: 967   NAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATM 1026
              + I GY +++  + S +W    E    T   +T L  G  Y +RV + N  G S+ +  
Sbjct: 13616 GSRIKGYIVERCPRGSDKWVACGEPVAETKMEVTGLEEGKWYAYRVKALNRQGASKPSRP 13675

Query: 1027  TKESAVIARDGKIYKNPVYEDFDFSEAP---MFTQPLVNTYAIAGYNATLNCSVRGNPKP 1083
             T+E   +               D  EAP   +  + L      AG    L  +V G P+P
Sbjct: 13676 TEEIQAV---------------DTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEP 13720

Query: 1084  KITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLG 1133
             KITW K  + +  D R  + +     T+ I      D GTY  +AVN  G
Sbjct: 13721 KITWTKADMILKQDKRITIENVPKKSTVTIVDSKRSDTGTYIIEAVNVCG 13770



 Score =  157 bits (397), Expect = 5e-38
 Identities = 146/550 (26%), Positives = 232/550 (42%), Gaps = 42/550 (7%)

Query: 385   ELEC-EVSEDDANVKWFK----NGEEII-----------PGPKSRYRIRVEGKKHILIIE 428
             ELE   +S+D   ++W K     G+EI+              K   + R++ K+    I 
Sbjct: 30436 ELEILSISKDSVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERIKDKQ--FTIG 30493

Query: 429   GATKADAAEYSVMT---TGGQSSAKLSVDLKPLK-------ILTPLTDQTVNLGKEICLK 478
             G  +A   E+ V     TG     + ++ +K          I   + D T  LG+   L 
Sbjct: 30494 GLLEATEYEFRVFAENETGLSRPRRTAMSIKTKLTSGEAPGIRKEMKDVTTKLGEAAQLS 30553

Query: 479   CEI-SENIPG-KWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDY--VFAPDAYN 534
             C+I    +P  KW + G  + +S + K+   GR H L +     EDEG Y  +   +   
Sbjct: 30554 CQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVGE 30613

Query: 535   VTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEG 594
             V   +K+ +   P+    G           G+ LRL +   G P P   W  G K +++ 
Sbjct: 30614 VETSSKLLLQATPQFH-PGYPLKEKYYGAVGSTLRLHVMYIGRPVPAMTWFHGQK-LLQN 30671

Query: 595   SGRIRTESYPDSSTLVI-DIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTV 653
             S  I  E+    + LV+ ++  +  +G Y + L N  G   A + V++ D PD P  P V
Sbjct: 30672 SENITIENTEHYTHLVMKNVQRKTHAGKYKVQLSNVFGTVDAILDVEIQDKPDKPTGPIV 30731

Query: 654   TE-VGDDWCIMNWEPPAYDGGSPILGYFIER-KKKQSSRWMRLNFDLCKETTFEPKKMIE 711
              E +  +  +++W+PPA DGGS I  Y +E+ + K+ + W  ++  +   TT     + E
Sbjct: 30732 IEALLKNSAVISWKPPADDGGSWITNYVVEKCEAKEGAEWQLVSSAI-SVTTCRIVNLTE 30790

Query: 712   GVAYEVRIFAVNAIGISKPSMPSRPFV---PLAVTSPPTLLTVDSVTDTTVTMRWRPPDH 768
                Y  R+ A N  GIS P   S   +   P      P   T+ +VT  +  + W+PP  
Sbjct: 30791 NAGYYFRVSAQNTFGISDPLEVSSVVIIKSPFEKPGAPGKPTITAVTKDSCVVAWKPPAS 30850

Query: 769   IGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEP 828
              G A +  Y LE   +    WI    + I +T F++  L    +   RVK  N  G SE 
Sbjct: 30851 DGGAKIRNYYLEKREKKQNKWISVTTEEIRETVFSVKNLIEGLEYEFRVKCENLGGESEW 30910

Query: 829   KYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEID 888
                S+PI  K  +          L+   +R    A  LV    G P+P + W + G EI 
Sbjct: 30911 SEISEPITPKSDVPIQAPHFKEELRNLNVRYQSNA-TLVCKVTGHPKPIVKWYRQGKEII 30969

Query: 889   KNQINIRNSE 898
              + +  R  E
Sbjct: 30970 ADGLKYRIQE 30979



 Score =  156 bits (395), Expect = 9e-38
 Identities = 103/340 (30%), Positives = 163/340 (47%), Gaps = 15/340 (4%)

Query: 516   ANALTEDEGDYVFAPDAYNVT---LPAKVHVIDPPKIILDGLDA----DNTVTVIAGNKL 568
             A  LTE + +Y F   A N      P+++ V+    ++   LD     D        +  
Sbjct: 19942 AKDLTEGK-EYTFRVSAENENGEGTPSEITVVARDDVVAPDLDLKGLPDLCYLAKENSNF 20000

Query: 569   RLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKN 628
             RL+IPI G+P P   W +G+  +   + R+  ES   ++TL++   ++ D+G Y I LKN
Sbjct: 20001 RLKIPIKGKPAPSVSWKKGEDPLATDT-RVSVESSAVNTTLIVYDCQKSDAGKYTITLKN 20059

Query: 629   EAGEAHASIKVKVVDFPDPPVAPT-VTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQ 687
              AG    +I +KVV  P  P  P    EV  +   + W PP  DGGS I  Y +E++   
Sbjct: 20060 VAGTKEGTISIKVVGKPGIPTGPIKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDSV 20119

Query: 688   SSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFV---PLAVTS 744
             +++W+       ++TTF   ++ EG+ Y  R+ A N  G+ +  + S P V   P  V  
Sbjct: 20120 NNKWVTCA-SAVQKTTFRVTRLHEGMEYTFRVSAENKYGVGE-GLKSEPIVARHPFDVPD 20177

Query: 745   PPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTI 804
              P    +  V   +V++ W  P   G + + GY LE+    +  W  ANK  I    F +
Sbjct: 20178 APPPPNIVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTPIRMRDFKV 20237

Query: 805   TGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPP 844
             TGL    +   RV A+N AG  +P   S+P++  + I+PP
Sbjct: 20238 TGLTEGLEYEFRVMAINLAGVGKPSLPSEPVVALDPIDPP 20277



 Score =  155 bits (391), Expect = 3e-37
 Identities = 98/310 (31%), Positives = 156/310 (50%), Gaps = 8/310 (2%)

Query: 547   PKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDS 606
             P++ L G+     V   AG+ +++EIP+ G P P   W +GD+ I++ + R+  E+   S
Sbjct: 21063 PELDLRGI-YQKLVIAKAGDNIKVEIPVLGRPKPTVTWKKGDQ-ILKQTQRVNFETTATS 21120

Query: 607   STLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPT-VTEVGDDWCIMNW 665
             + L I+   R DSG Y +  +N  GE    I ++V D P PP  P    EV  D+   +W
Sbjct: 21121 TILNINECVRSDSGPYPLTARNIVGEVGDVITIQVHDIPGPPTGPIKFDEVSSDFVTFSW 21180

Query: 666   EPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAI 725
             +PP  DGG PI  Y +E ++  S+ W+ L   + + TT++  ++  G+ Y+ R+ A N  
Sbjct: 21181 DPPENDGGVPISNYVVEMRQTDSTTWVELATTVIR-TTYKATRLTTGLEYQFRVKAQNRY 21239

Query: 726   GISKPSMPSRPFV---PLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYC 782
             G+  P + S   V   P  V  PP    V +VT  ++T+ W  P   G + + GY +E  
Sbjct: 21240 GVG-PGITSACIVANYPFKVPGPPGTPQVTAVTKDSMTISWHEPLSDGGSPILGYHVERK 21298

Query: 783   FEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIE 842
                   W   +K L+    F  +GL        RV A N AG S+P   S+P+L  + I+
Sbjct: 21299 ERNGILWQTVSKALVPGNIFKSSGLTDGIAYEFRVIAENMAGKSKPSKPSEPMLALDPID 21358

Query: 843   PPKIRIPRHL 852
             PP   +P ++
Sbjct: 21359 PPGKPVPLNI 21368



 Score =  154 bits (389), Expect = 5e-37
 Identities = 103/318 (32%), Positives = 157/318 (49%), Gaps = 10/318 (3%)

Query: 530   PDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDK 589
             P   +V + AK  VI P   +L      NT TV+AG  L++++P  G P P   W + D 
Sbjct: 22132 PRQLSVPVIAKDLVIPPAFKLLF-----NTFTVLAGEDLKVDVPFIGRPTPAVTWHK-DN 22185

Query: 590   AIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPV 649
               ++ + R+  ES  ++S L I  A R+D G Y + L N AGEA  ++ V V+D P PP 
Sbjct: 22186 VPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAGEAIETLNVIVLDKPGPPT 22245

Query: 650   APT-VTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKK 708
              P  + EV  D   ++W PP YDGGS I  Y +E++   ++ W  ++  + + TT +  +
Sbjct: 22246 GPVKMDEVTADSITLSWGPPKYDGGSSINNYIVEKRDTSTTTWQIVSATVAR-TTIKACR 22304

Query: 709   MIEGVAYEVRIFAVNAIGISK--PSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPP 766
             +  G  Y+ RI A N  G S    S P+    P  V  PP    V   +  ++ ++W  P
Sbjct: 22305 LKTGCEYQFRIAAENRYGKSTYLNSEPTVAQYPFKVPGPPGTPVVTLSSRDSMEVQWNEP 22364

Query: 767   DHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGAS 826
                G + + GY LE     +  W+  NK  I +TKF  TGL    +   RV A N  G  
Sbjct: 22365 ISDGGSRVIGYHLERKERNSILWVKLNKTPIPQTKFKTTGLEEGVEYEFRVSAENIVGIG 22424

Query: 827   EPKYYSQPILVKEIIEPP 844
             +P   S+  + ++  +PP
Sbjct: 22425 KPSKVSECYVARDPCDPP 22442



 Score =  150 bits (380), Expect = 5e-36
 Identities = 211/898 (23%), Positives = 350/898 (38%), Gaps = 95/898 (10%)

Query: 279  FAKILDPAYQVDKGGRVRFVVELA-DPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFIN 337
            F K L+P+  V +    R+  ++   P+++V WYK+  EI+ S+K+         +L ++
Sbjct: 7307 FIKKLEPSRIVKQDEFTRYECKIGGSPEIKVLWYKDETEIQESSKFRMSFVDSVAVLEMH 7366

Query: 338  NCQMTDDSEY----YVTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEV-SE 392
            N  + D  +Y    +  AG    ST L V+EPPI   K+        G  V LECE+   
Sbjct: 7367 NLSVEDSGDYTCEAHNAAGSASSSTSLKVKEPPIF-RKKPHPIETLKGADVHLECELQGT 7425

Query: 393  DDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTG--GQSSAK 450
               +V W+K+  E+  G K  Y+I  E     + I     AD  EY    T   G  +  
Sbjct: 7426 PPFHVSWYKDKRELRSGKK--YKIMSENFLTSIHILNVDAADIGEYQCKATNDVGSDTCV 7483

Query: 451  LSVDLK-PLKILTPLTDQTVNLGKEICLKCEI--SENIPGKWTKN-GLPVQESDRLKVVH 506
             S+ LK P + +  L+D +  +GKE+ L+  I  +E I   W K+ G  V+ESD + + +
Sbjct: 7484 GSIALKAPPRFVKKLSDISTVVGKEVQLQTTIEGAEPISVVWFKDKGEIVRESDNIWISY 7543

Query: 507  KGRIHKLVIANALTEDEGDYV--FAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIA 564
               I  L  +     + G Y      DA      A + V++P  I+    +   ++ V  
Sbjct: 7544 SENIATLQFSRVEPANAGKYTCQIKNDAGMQECFATLSVLEPATIV----EKPESIKVTT 7599

Query: 565  GNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHI 624
            G+   LE  ++G P     W +  K  +    + +   +   S L I      DSGVY  
Sbjct: 7600 GDTCTLECTVAGTPELSTKWFKDGKE-LTSDNKYKISFFNKVSGLKIINVAPSDSGVYSF 7658

Query: 625  NLKNEAGEAHASIKVKVVDFPDPP--VAPTVTEVGDDWCIMNWEPPAYDGGSPI-LGYFI 681
             ++N  G+   +  ++V D   PP          G     +  E   Y G  PI + +F 
Sbjct: 7659 EVQNPVGKDSCTASLQVSDRTVPPSFTRKLKETNGLSGSSVVMECKVY-GSPPISVSWFH 7717

Query: 682  ERKKKQSSRWMR--LNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVP 739
            E  +  S R  +  L  + C  T      + E  + +    A N  G  + S       P
Sbjct: 7718 EGNEISSGRKYQTTLTDNTCALTV---NMLEESDSGDYTCIATNMAGSDECS------AP 7768

Query: 740  LAVTSPPTLL----TVDSVTDTTVT----MRWRPPDHIGAAGLDGYVL--EYCFEGTEDW 789
            L V  PP+ +     +D +T T VT    ++  PP  +        ++  + C    ED 
Sbjct: 7769 LTVREPPSFVQKPDPMDVLTGTNVTFTSIVKGTPPFSVSWFKGSSELVPGDRCNVSLED- 7827

Query: 790  IVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIP 849
             VA  +L D      T    +    V  +A  A+  +     +    VK +         
Sbjct: 7828 SVAELELFD----VDTSQSGEYTCIVSNEAGKASCTTHLYIKAPAKFVKRL--------- 7874

Query: 850  RHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQ-INIRNSETDTIIFIRKA 908
                  Y    G+ + L   F G P   +TWKK+G  +  +Q  NI  +E   I+ I  +
Sbjct: 7875 ----NDYSIEKGKPLILEGTFTGTPPISVTWKKNGINVTPSQRCNITTTEKSAILEIPSS 7930

Query: 909  ERSHSGKYDLQVKVDKFVETASIDIQIIDRPG-----PPQIVKIEDVWGENVALTWTPPK 963
                +G+Y+  ++     ++ S  I I++ P       P  V + D       L  TP  
Sbjct: 7931 TVEDAGQYNCYIENASGKDSCSAQILILEPPYFVKQLEPVKVSVGDSASLQCQLAGTPE- 7989

Query: 964  DDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSED 1023
                    G +  K D K     T   H+    AT+            VF++     S +
Sbjct: 7990 -------IGVSWYKGDTKLRPTTTYKMHFRNNVATL------------VFNQVDINDSGE 8030

Query: 1024 ATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKP 1083
                 E++V    G++  +      +    P F++ L +     G     +C++ G+   
Sbjct: 8031 YICKAENSV----GEVSASTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFDCAISGSEPI 8086

Query: 1084 KITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKL 1141
             ++W K+   + D P  +        TL I K      G Y C A N +G+     +L
Sbjct: 8087 SVSWYKDGKPLKDSPNVQTSFLDNTATLNIFKTDRSLAGQYSCTATNPIGSASSSARL 8144



 Score =  149 bits (375), Expect = 2e-35
 Identities = 97/304 (31%), Positives = 142/304 (46%), Gaps = 5/304 (1%)

Query: 544   IDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESY 603
             ID P   LD    D  + V AG    LE  I G+P P  +WS+  K + E + R+  +S 
Sbjct: 24702 IDAPNASLDPKYKD-VIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKST 24760

Query: 604   PDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPT-VTEVGDDWCI 662
                +TLV+    R D G Y + L N  G     I VKV+D P PP  P  VT V  + C 
Sbjct: 24761 IQKTTLVVKDCIRTDGGQYILKLSNVGGTKSIPITVKVLDRPGPPEGPLKVTGVTAEKCY 24820

Query: 663   MNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAV 722
             + W PP  DGG+ I  Y IE+++     W +++ ++ +   ++  K++ G  Y  R+ AV
Sbjct: 24821 LAWNPPLQDGGANISHYIIEKRETSRLSWTQVSTEV-QALNYKVTKLLPGNEYIFRVMAV 24879

Query: 723   NAIGISKP--SMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLE 780
             N  GI +P  S P     P     PP+   V ++T  ++ + W  P   G   ++GY+LE
Sbjct: 24880 NKYGIGEPLESGPVTACNPYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILE 24939

Query: 781   YCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEI 840
                +    W   NK  +   +  +TGL        RV A NAAG  EP   S      + 
Sbjct: 24940 KRDKEGVRWTKCNKKTLTDLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRACDA 24999

Query: 841   IEPP 844
             + PP
Sbjct: 25000 LYPP 25003



 Score =  147 bits (372), Expect = 4e-35
 Identities = 207/916 (22%), Positives = 365/916 (39%), Gaps = 118/916 (12%)

Query: 274  KKSAAFAKILDPAYQVDKGGRVRFVVEL-ADPKLEVKWYKNGQEIRPSTKYIFEHKGCQR 332
            ++  +F K +DP+Y +  G   R   +L   P ++V W+KN +E+  S          + 
Sbjct: 3734 REPPSFVKKVDPSYLMLPGESARLHCKLKGSPVIQVTWFKNNKELSESNTVRMYFVNSEA 3793

Query: 333  ILFINNCQMTDDSEYYVTA----GDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELEC 388
            IL I + ++ D   Y   A    G + CSTE+ ++EPP  + K LE      G    L+C
Sbjct: 3794 ILDITDVKVEDSGSYSCEAVNDVGSDSCSTEIVIKEPPSFI-KTLEPADIVRGTNALLQC 3852

Query: 389  EVSEDDA-NVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIE--GATKADAAEYSVMTTG- 444
            EVS      + WFK+ ++I    +S  + R+  +K ++ +E      AD  EY  +    
Sbjct: 3853 EVSGTGPFEISWFKDKKQI----RSSKKYRLFSQKSLVCLEIFSFNSADVGEYECVVANE 3908

Query: 445  -GQSSAKLSVDLKPLKILTPLTDQTVNLGKE-ICLKCEI--SENIPGKWTKNGLPVQESD 500
             G+     +  LK         D  + LG + + L+  +  SE I   W K    ++E  
Sbjct: 3909 VGKCGCMATHLLKEPPTFVKKVDDLIALGGQTVTLQAAVRGSEPISVTWMKGQEVIREDG 3968

Query: 501  RLKVVHKGRIHKLVIANALTEDEGDYVFAPD--AYNVTLPAKVHVIDPPKIILDGLDADN 558
            ++K+     +  L+I +      G Y    +  A + T   ++ V +P KII    +   
Sbjct: 3969 KIKMSFSNGVAVLIIPDVQISFGGKYTCLAENEAGSQTSVGELIVKEPAKII----ERAE 4024

Query: 559  TVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDD 618
             + V AG+   LE  ++G P  K  W +  + ++  S + R     + + L    AE  D
Sbjct: 4025 LIQVTAGDPATLEYTVAGTPELKPKWYKDGRPLV-ASKKYRISFKNNVAQLKFYSAELHD 4083

Query: 619  SGVYHINLKNEAGEAHASIKVKVVDFPDPPVAP----TVTEVGDDWCIMNWEPPAYDGGS 674
            SG Y   + NE G +       V+D    P        V  V +  C ++ +     G  
Sbjct: 4084 SGQYTFEISNEVGSSSCETTFTVLDRDIAPFFTKPLRNVDSVVNGTCRLDCK---IAGSL 4140

Query: 675  PI-LGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMP 733
            P+ + +F + K+  +S   R+ F +    + E  ++    A      A N++G SK S  
Sbjct: 4141 PMRVSWFKDGKEIAASDRYRIAF-VEGTASLEIIRVDMNDAGNFTCRATNSVG-SKDSSG 4198

Query: 734  SRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEG----TEDW 789
            +     L V  PP+ +T     D             G+A      L+  F+G    T  W
Sbjct: 4199 A-----LIVQEPPSFVTKPGSKDVLP----------GSA----VCLKSTFQGSTPLTIRW 4239

Query: 790  IVANKDLIDKTKFTIT--GLPTDAKIFV---------RVKAVNAAGASEPK---YYSQPI 835
               NK+L+      IT   L +  ++++           K  N AG  E     +  +P 
Sbjct: 4240 FKGNKELVSGGSCYITKEALESSLELYLVKTSDSGTYTCKVSNVAGGVECSANLFVKEPA 4299

Query: 836  LVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEI-DKNQINI 894
               E +EP ++     LK+      G+A  L     G P  ++TW  +  EI + ++  +
Sbjct: 4300 TFVEKLEPSQL-----LKK------GDATQLACKVTGTPPIKITWFANDREIKESSKHRM 4348

Query: 895  RNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRP------GPPQIVKIE 948
               E+  ++ +       SG+Y  + + +   +  S  + + + P       P +++K  
Sbjct: 4349 SFVESTAVLRLTDVGIEDSGEYMCEAQNEAGSDHCSSIVIVKESPYFTKEFKPIEVLKEY 4408

Query: 949  DVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEY 1008
            DV      +  TPP +     IT +      +   ++ T I+  H  S  I + V  +  
Sbjct: 4409 DVM-LLAEVAGTPPFE-----ITWFKDNTILRSGRKYKTFIQD-HLVSLQILKFVAADA- 4460

Query: 1009 YFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAG 1068
                  E  C ++ +   +  SA +                  E P F + + +T ++ G
Sbjct: 4461 -----GEYQCRVTNEVGSSICSARVT---------------LREPPSFIKKIESTSSLRG 4500

Query: 1069 YNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKA 1128
              A    +++G+    +TW+K+   I +D   RM     V +L +        G Y C+A
Sbjct: 4501 GTAAFQATLKGSLPITVTWLKDSDEITEDDNIRMTFENNVASLYLSGIEVKHDGKYVCQA 4560

Query: 1129 VNDLGTVEIECKLEVK 1144
             ND G       L VK
Sbjct: 4561 KNDAGIQRCSALLSVK 4576



 Score =  146 bits (369), Expect = 1e-34
 Identities = 189/864 (21%), Positives = 334/864 (38%), Gaps = 120/864 (13%)

Query: 297   FVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKC 356
             F VEL+   + VKW+KN Q +  +     + +G    +   +  + D S+  V A     
Sbjct: 11948 FTVELSHDNIRVKWFKNDQRLHTTRSVSMQDEGKTHSITFKDLSIDDTSQIRVEAMGMSS 12007

Query: 357   STELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRI 416
               +L V E     T +L+D T    + V L+CE+S+ DA VKWFK+G+EI P   +   I
Sbjct: 12008 EAKLTVLEGDPYFTGKLQDYTGVEKDEVILQCEISKADAPVKWFKDGKEIKPSKNA--VI 12065

Query: 417   RVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEIC 476
             + +GKK +LI++ A K+D  +Y+      ++S KL ++ + +K++ PL    V   +   
Sbjct: 12066 KADGKKRMLILKKALKSDIGQYTCDCGTDKTSGKLDIEDREIKLVRPLHSVEVMETETAR 12125

Query: 477   LKCEISE-NIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNV 535
              + EISE +I   W   G  + ++   ++  +G+IH LV+ N   +  G   F   A NV
Sbjct: 12126 FETEISEDDIHANWKLKGEALLQTPDCEIKEEGKIHSLVLHNCRLDQTGGVDF--QAANV 12183

Query: 536   TLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGS 595
                A + V   P++I   L     VTV AG     +  +S E  P   + +G K  +E S
Sbjct: 12184 KSSAHLRV--KPRVI-GLLRPLKDVTVTAGETATFDCELSYEDIPVEWYLKGKK--LEPS 12238

Query: 596   GRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTE 655
              ++   S     TL +   + +D+G   +  K+    A+  +K   V+F  P    TV E
Sbjct: 12239 DKVVPRSEGKVHTLTLRDVKLEDAGEVQLTAKDFKTHANLFVKEPPVEFTKPLEDQTVEE 12298

Query: 656   VGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFE------PKKM 709
                             G + +L   + R+  +  +W +   ++ K   +E       +K+
Sbjct: 12299 ----------------GATAVLECEVSRENAK-VKWFKNGTEILKSKKYEIVADGRVRKL 12341

Query: 710   I--EGVAYEVRIFAVNA--------IGISKPSMP-SRPFVPLAVTSPPTLLTVDSVTDTT 758
             +  +    +++ +  +A        + +  P +   RP   L V           ++   
Sbjct: 12342 VIHDCTPEDIKTYTCDAKDFKTSCNLNVVPPHVEFLRPLTDLQVREKEMARFECELSREN 12401

Query: 759   VTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVK 818
               ++W      GA    G   +   +G    +V NK L+D           +A+    V+
Sbjct: 12402 AKVKWFKD---GAEIKKGKKYDIISKGAVRILVINKCLLD----------DEAEYSCEVR 12448

Query: 819   AVNAAG----ASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKP 874
                 +G      E   +++ +   E+ E   I++   +                    KP
Sbjct: 12449 TARTSGMLTVLEEEAVFTKNLANIEVSETDTIKLVCEV-------------------SKP 12489

Query: 875   RPELTWKKDGAE-IDKNQINIRNSETDTIIFIRKAERSHSGKYDLQV---KVDKFVETAS 930
               E+ W K   E I+  +  I       I+ I+ A    +G Y+ ++   + D  V+   
Sbjct: 12490 GAEVIWYKGDEEIIETGRYEILTEGRKRILVIQNAHLEDAGNYNCRLPSSRTDGKVKVHE 12549

Query: 931   IDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQ-KADKKSMEWFTVI 989
             +  + I +P   +I++     GE      +  K+        + +Q K D K++E     
Sbjct: 12550 LAAEFISKPQNLEILE-----GEKAEFVCSISKE-------SFPVQWKRDDKTLE----- 12592

Query: 990   EHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFD 1049
                            G++Y      +    + +DAT+      +   G            
Sbjct: 12593 --------------SGDKYDVIADGKKRVLVVKDATLQDMGTYVVMVGAA---RAAAHLT 12635

Query: 1050  FSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVC 1109
               E      PL +T          NC V      K  W +N+ AI D  +Y +     V 
Sbjct: 12636 VIEKLRIVVPLKDTRVKEQQEVVFNCEV-NTEGAKAKWFRNEEAIFDSSKYIILQKDLVY 12694

Query: 1110  TLEIRKPSPYDGGTYCCKAVNDLG 1133
             TL IR     D   Y     N  G
Sbjct: 12695 TLRIRDAHLDDQANYNVSLTNHRG 12718



 Score =  146 bits (369), Expect = 1e-34
 Identities = 96/339 (28%), Positives = 169/339 (49%), Gaps = 21/339 (6%)

Query: 521   EDEGDYVF---APDAYNVTLPAK----VHVID---PPKIILDGLDADNTVTVIAGNKLRL 570
             E++  Y F   A  A N++ P++    V ++    PP+I L  +   + +TV AG  + L
Sbjct: 19257 EEKAQYQFRAIARTAVNISPPSEPSDPVTILAENVPPRIDLS-VAMKSLLTVKAGTNVCL 19315

Query: 571   EIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEA 630
             +  + G+P P   W + D  +++ +  I+     +  TL +    R DSG Y I  +N +
Sbjct: 19316 DATVFGKPMPTVSWKK-DGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTITAENSS 19374

Query: 631   GEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSR 690
             G   A+IK+KV+D P PP +  + ++  D  +++WEPP  DGGS I  Y +++++     
Sbjct: 19375 GSKSATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYIVDKRETSRPN 19434

Query: 691   WMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGI-----SKPSMPSRPFVPLAVTSP 745
             W +++  +   T+   +K+IEG  Y+ RI A N  G+     ++P++   P+ P     P
Sbjct: 19435 WAQVSATV-PITSCSVEKLIEGHEYQFRICAENKYGVGDPVFTEPAIAKNPYDPPGRCDP 19493

Query: 746   PTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTIT 805
             P    + ++T   +T+ W+PP   G + + GY+LE       +W   N+  I +     T
Sbjct: 19494 P---VISNITKDHMTVSWKPPADDGGSPITGYLLEKRETQAVNWTKVNRKPIIERTLKAT 19550

Query: 806   GLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPP 844
             GL    +   RV A+N AG  +P   S+    ++   PP
Sbjct: 19551 GLQEGTEYEFRVTAINKAGPGKPSDASKAAYARDPQYPP 19589



 Score =  145 bits (365), Expect = 3e-34
 Identities = 110/374 (29%), Positives = 173/374 (46%), Gaps = 19/374 (5%)

Query: 288   QVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEY 347
             QV +    RF  EL+    +VKW+K+G EI+   KY    KG  RIL IN C + D++EY
Sbjct: 12384 QVREKEMARFECELSRENAKVKWFKDGAEIKKGKKYDIISKGAVRILVINKCLLDDEAEY 12443

Query: 348   YVTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEII 407
                    + S  L V E   + TK L +      + ++L CEVS+  A V W+K  EEII
Sbjct: 12444 SCEVRTARTSGMLTVLEEEAVFTKNLANIEVSETDTIKLVCEVSKPGAEVIWYKGDEEII 12503

Query: 408   PGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQ 467
                  RY I  EG+K IL+I+ A   DA  Y+      ++  K+ V     + ++   + 
Sbjct: 12504 --ETGRYEILTEGRKRILVIQNAHLEDAGNYNCRLPSSRTDGKVKVHELAAEFISKPQNL 12561

Query: 468   TVNLGKEICLKCEIS-ENIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDY 526
              +  G++    C IS E+ P +W ++   ++  D+  V+  G+   LV+ +A  +D G Y
Sbjct: 12562 EILEGEKAEFVCSISKESFPVQWKRDDKTLESGDKYDVIADGKKRVLVVKDATLQDMGTY 12621

Query: 527   VF----APDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKA 582
             V     A  A ++T+  K+ ++ P K        D  V          E+   G    KA
Sbjct: 12622 VVMVGAARAAAHLTVIEKLRIVVPLK--------DTRVKEQQEVVFNCEVNTEG---AKA 12670

Query: 583   MWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVV 642
              W R ++AI + S  I  +      TL I  A  DD   Y+++L N  GE   S    +V
Sbjct: 12671 KWFRNEEAIFDSSKYIILQK-DLVYTLRIRDAHLDDQANYNVSLTNHRGENVKSAANLIV 12729

Query: 643   DFPDPPVAPTVTEV 656
             +  D  +   + ++
Sbjct: 12730 EEEDLRIVEPLKDI 12743



 Score =  144 bits (362), Expect = 6e-34
 Identities = 89/302 (29%), Positives = 150/302 (49%), Gaps = 8/302 (2%)

Query: 547   PKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDS 606
             P   L G+  +  +T  AG+   +++PISG P PK  W   +  + E + R+   +  D 
Sbjct: 28645 PTADLTGI-TNQLITCKAGSPFTIDVPISGRPAPKVTWKLEEMRLKE-TDRVSITTTKDR 28702

Query: 607   STLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPT-VTEVGDDWCIMNW 665
             +TL +  + R DSG Y + L+N AG    S+ V V+  P P   P  V+ V  + C+++W
Sbjct: 28703 TTLTVKDSMRGDSGRYFLTLENTAGVKTFSVTVVVIGRPGPVTGPIEVSSVSAESCVLSW 28762

Query: 666   EPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAI 725
               P   GG+ I  Y +E+++  ++ W  +N  + K T  +   + + + Y  R+ + N  
Sbjct: 28763 GEPKDGGGTEITNYIVEKRESGTTAWQLVNSSV-KRTQIKVTHLTKYMEYSFRVSSENRF 28821

Query: 726   GISKPSMPSRPFV---PLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYC 782
             G+SKP + S P +   P    S PT   V  V+   +++RW  P H G + + GY +E  
Sbjct: 28822 GVSKP-LESAPIIAEHPFVPPSAPTRPEVYHVSANAMSIRWEEPYHDGGSKIIGYWVEKK 28880

Query: 783   FEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIE 842
                T  W+  NK    +  + +TGL    +   R  A+NAAG S+    S+PI+ +  ++
Sbjct: 28881 ERNTILWVKENKVPCLECNYKVTGLVEGLEYQFRTYALNAAGVSKASEASRPIMAQNPVD 28940

Query: 843   PP 844
              P
Sbjct: 28941 AP 28942



 Score =  142 bits (359), Expect = 1e-33
 Identities = 133/536 (24%), Positives = 207/536 (38%), Gaps = 70/536 (13%)

Query: 642   VDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKE 701
             +D P PP  PTV +VG     +NW  P +DGG+ I  Y IE  K  +  W+R+   +   
Sbjct: 13981 IDPPWPPGKPTVKDVGKTSVRLNWTKPEHDGGAKIESYVIEMLKTGTDEWVRVAEGVPTT 14040

Query: 702   TTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFV---PLAVTSPPTLLTVDSVTDTT 758
                 P  M EG  Y  R+ AVN  G S+PS PS P +    L   SPP  L V ++T  T
Sbjct: 14041 QHLLPGLM-EGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLEVINITKNT 14099

Query: 759   VTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVK 818
               ++W  P+  G + +  Y++E      + W   +  + D TK T+T L   +    RV 
Sbjct: 14100 ADLKWTVPEKDGGSPITNYIVEKRDVRRKGWQTVDTTVKD-TKCTVTPLTEGSLYVFRVA 14158

Query: 819   AVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPEL 878
             A NA G S+       +L K+    P                G    L +    K   +L
Sbjct: 14159 AENAIGQSDYTEIEDSVLAKDTFTTP----------------GPPYALAVVDVTKRHVDL 14202

Query: 879   TW---KKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQI 935
              W   K DG    +  +  +     T    R  +   +   D   +V   +E   +  Q+
Sbjct: 14203 KWEPPKNDGGRPIQRYVIEKKERLGT----RWVKAGKTAGPDCNFRVTDVIEGTEVQFQV 14258

Query: 936   -----------------------IDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITG 972
                                       P PP  + + D   +++A+ W PP+ +G + I G
Sbjct: 14259 RAENEAGVGHPSEPTEILSIEDPTSPPSPPLDLHVTDAGRKHIAIAWKPPEKNGGSPIIG 14318

Query: 973   YTIQKADKKSMEWFTVIEHYHRTSATITE--LVIGNEYYFRVFSENMCGLSEDATMTKES 1030
             Y ++     + +W  V     +      E  +V   EY  RV + N  G+SE + +++  
Sbjct: 14319 YHVEMCPVGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAIGVSEPSEISEN- 14377

Query: 1031  AVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKN 1090
              V+A+D         E  D                I G   ++    R  P P ++W K+
Sbjct: 14378 -VVAKDPDCKPTIDLETHDI-------------IVIEGEKLSIPVPFRAVPVPTVSWHKD 14423

Query: 1091  KVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVKVI 1146
                +    R  M ++     LE+ K    D G Y     N LG+      + VKVI
Sbjct: 14424 GKEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSA--TASINVKVI 14477



 Score =  140 bits (352), Expect = 9e-33
 Identities = 91/298 (30%), Positives = 146/298 (48%), Gaps = 7/298 (2%)

Query: 546   PPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPD 605
             PPK  LD     + VT+ AG+ L L+  + G+P PK +W++GDK  ++   ++  +    
Sbjct: 29043 PPKAELDARLHGDLVTIRAGSDLVLDAAVGGKPEPKIIWTKGDKE-LDLCEKVSLQYTGK 29101

Query: 606   SSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNW 665
              +T VI   +R DSG Y + +KN +G    S+ VKV+D P P    TV+ V  + C + W
Sbjct: 29102 RATAVIKFCDRSDSGKYTLTVKNASGTKAVSVMVKVLDSPGPCGKLTVSRVTQEKCTLAW 29161

Query: 666   EPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAI 725
               P  DGG+ I  Y +ER++     W+ +  + C   ++   ++I+   Y  R+ AVN  
Sbjct: 29162 SLPQEDGGAEITHYIVERRETSRLNWVIVEGE-CPTLSYVVTRLIKNNEYIFRVRAVNKY 29220

Query: 726   GISKPSMPSRPFV---PLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYC 782
             G   P + S P V      + SPP +          + ++W  P+  G   +  Y+++  
Sbjct: 29221 GPGVP-VESEPIVARNSFTIPSPPGIPEEVGTGKEHIIIQWTKPESDGGNEISNYLVDKR 29279

Query: 783   FEGTEDWIVANKD-LIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKE 839
              + +  W   NKD ++  T+  +T L        RV AVNAAG SEP   S  I  +E
Sbjct: 29280 EKKSLRWTRVNKDYVVYDTRLKVTSLMEGCDYQFRVTAVNAAGNSEPSEASNFISCRE 29337



 Score =  139 bits (350), Expect = 2e-32
 Identities = 158/612 (25%), Positives = 260/612 (42%), Gaps = 77/612 (12%)

Query: 292   GGRVRFVVELAD-PKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVT 350
             GG +R  V +   P  EVKW K   EIR +   I +       L ++N    D  +Y +T
Sbjct: 22957 GGSLRLFVPIKGRPTPEVKWGKVDGEIRDAA--IIDVTSSFTSLVLDNVNRYDSGKYTLT 23014

Query: 351   AGDEKCSTELFVR-------EPPI--MVTKQLEDTTAYCGERVELECE-------VSEDD 394
               +   +   FV         PP+   VT+  +D+ +   E   L+         V + +
Sbjct: 23015 LENSSGTKSAFVTVRVLDTPSPPVNLKVTEITKDSVSITWEPPLLDGGSKIKNYIVEKRE 23074

Query: 395   ANVKWF--------KNG---EEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTT 443
             A  K +        KN    +++  G    +R+  E +  I        A  A+   +  
Sbjct: 23075 ATRKSYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAENEYGI-----GLPAQTADPIKVAE 23129

Query: 444   GGQSSAKLSVDLKPLKILTPLTDQTVNLG---KEICLKCEISENIPGKWTKNGLPVQESD 500
               Q   K++VD         +T  +V+L     E     +I + I     K+     E  
Sbjct: 23130 VPQPPGKITVD--------DVTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKHSEKWSECA 23181

Query: 501   RLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYN-----------VTLPAKVHVIDPPKI 549
             R+K +      + VI N LT+ E +Y+F   A N           V + AK  VI+P   
Sbjct: 23182 RVKSL------QAVITN-LTQGE-EYLFRVVAVNEKGRSDPRSLAVPIVAKDLVIEP--- 23230

Query: 550   ILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTL 609
               D   A ++ +V  G  L++E+PISG P P   W++ D   ++ + RI      D +TL
Sbjct: 23231 --DVKPAFSSYSVQVGQDLKIEVPISGRPKPTITWTK-DGLPLKQTTRINVTDSLDLTTL 23287

Query: 610   VIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPT-VTEVGDDWCIMNWEPP 668
              I    +DD G Y I + N  G+  ASI++  +D PDPP  P    +V  +   ++W PP
Sbjct: 23288 SIKETHKDDGGQYGITVANVVGQKTASIEIVTLDKPDPPKGPVKFDDVSAESITLSWNPP 23347

Query: 669   AYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGIS 728
              Y GG  I  Y ++++   ++ W  ++  + + TT +  K+  G  Y+ RIFA N  G S
Sbjct: 23348 LYTGGCQITNYIVQKRDTTTTVWDVVSATVAR-TTLKVTKLKTGTEYQFRIFAENRYGQS 23406

Query: 729   KPSMPSRPFV---PLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEG 785
               ++ S P V   P     PP      +++  ++ ++W  P + G + + GY LE     
Sbjct: 23407 F-ALESDPIVAQYPYKEPGPPGTPFATAISKDSMVIQWHEPVNNGGSPVIGYHLERKERN 23465

Query: 786   TEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPK 845
             +  W   NK +I  T+F    L    +   RV A N  G  +    S+  + ++  +PP 
Sbjct: 23466 SILWTKVNKTIIHDTQFKAQNLEEGIEYEFRVYAENIVGVGKASKNSECYVARDPCDPPG 23525

Query: 846   IRIPRHLKQTYI 857
                P  +K+  I
Sbjct: 23526 TPEPIMVKRNEI 23537



 Score =  138 bits (347), Expect = 3e-32
 Identities = 89/302 (29%), Positives = 146/302 (48%), Gaps = 6/302 (1%)

Query: 547   PKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDS 606
             P I+  G +  + + + +G  LR++  + G P P+  W + D   +E    +       S
Sbjct: 27955 PPIVEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVTWFK-DGVEIEKRMNMEITDVLGS 28013

Query: 607   STLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPT-VTEVGDDWCIMNW 665
             ++L +  A RD  GVY +  KN +G A A IKVKV D P   V P   T +  +   + W
Sbjct: 28014 TSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQDTPGKVVGPIRFTNITGEKMTLWW 28073

Query: 666   EPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAI 725
             + P  DG +PI  Y IE+++     W  +  D C+  ++   K+I G  Y+ R+ AVN  
Sbjct: 28074 DAPLNDGCAPITHYIIEKRETSRLAWALIE-DKCEAQSYTAIKLINGNEYQFRVSAVNKF 28132

Query: 726   GISKP--SMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCF 783
             G+ +P  S P    +   V   P +    ++T  ++T+ W  P+  G + +  Y+LE   
Sbjct: 28133 GVGRPLDSDPVVAQIQYTVPDAPGIPEPSNITGNSITLTWARPESDGGSEIQQYILERRE 28192

Query: 784   EGTEDWI-VANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIE 842
             + +  W+ V +K  I +T+F +TGL    +    V A NAAG       S+ I  +E + 
Sbjct: 28193 KKSTRWVKVISKRPISETRFKVTGLTEGNEYEFHVMAENAAGVGPASGISRLIKCREPVN 28252

Query: 843   PP 844
             PP
Sbjct: 28253 PP 28254



 Score =  136 bits (343), Expect = 1e-31
 Identities = 105/376 (27%), Positives = 169/376 (44%), Gaps = 13/376 (3%)

Query: 272  EEKKSAAFAKILDPAYQVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQ 331
            + K+   F + L      +K     F  E ++P ++VKWYK+G E+    KY        
Sbjct: 2169 QAKQLITFTQELQDVVAKEKDTMATFECETSEPFVKVKWYKDGMEVHEGDKYRMHSDRKV 2228

Query: 332  RILFINNCQMTDDSEY-YVTAGDE--KCSTELFVREPPIMVTKQLEDTTAYCGERVELEC 388
              L I     +D  +Y  V   DE  K + +L V    +   K+L+D         ELEC
Sbjct: 2229 HFLSILTIDTSDAEDYSCVLVEDENVKTTAKLIVEGAVVEFVKELQDIEVPESYSGELEC 2288

Query: 389  EVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSS 448
             VS ++   KW+ N  E+      +Y I     +  L ++  TK D  EYS +  G +++
Sbjct: 2289 IVSPENIEGKWYHNDVEL--KSNGKYTITSRRGRQNLTVKDVTKEDQGEYSFVIDGKKTT 2346

Query: 449  AKLSVDLKPLKILTPLTDQTVNLGKEICLKCEIS-ENIPGKWTKNGLPVQESDRLKVVHK 507
             KL +  +P+ IL  L+DQ V  G  + L+ ++S E++ G W K+G  VQ SDR+ +V  
Sbjct: 2347 CKLKMKPRPIAILQGLSDQKVCEGDIVQLEVKVSLESVEGVWMKDGQEVQPSDRVHIVID 2406

Query: 508  GRIHKLVIANALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNK 567
             + H L+I +   ED G+Y F   A  ++   +V V       +D +     V VI G K
Sbjct: 2407 KQSHMLLIEDMTKEDAGNYSFTIPALGLSTSGRVSVYS-----VDVITPLKDVNVIEGTK 2461

Query: 568  LRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLK 627
              LE  +S        W   D+ I +   R++         LVI+     D G Y + + 
Sbjct: 2462 AVLECKVSVPDVTSVKWYLNDEQI-KPDDRVQAIVKGTKQRLVINRTHASDEGPYKLIVG 2520

Query: 628  NEAGEAHASI-KVKVV 642
                  + S+ K+K++
Sbjct: 2521 RVETNCNLSVEKIKII 2536



 Score =  134 bits (338), Expect = 4e-31
 Identities = 201/832 (24%), Positives = 325/832 (39%), Gaps = 120/832 (14%)

Query: 362   VREPPIMVTKQLEDTTAY-CGERVELECEVS-EDDANVKWFKNGEEIIPGPKSRYRIRVE 419
             V  P I V  + +DT     GE   LE +VS      ++W K+G+E+     ++  I++ 
Sbjct: 21456 VEAPKIKVDVKFKDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKEL--EGTAKLEIKIA 21513

Query: 420   GKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKC 479
                  L+ + +T+ D+  Y++  T     AK   ++K L    P  +  + + +    KC
Sbjct: 21514 DFSTNLVNKDSTRRDSGAYTLTATNPGGFAKHIFNVKVLDRPGP-PEGPLAVTEVTSEKC 21572

Query: 480   EISENIP-----GKWTKNGLPVQESDRL---KVVHKGRIHKLVIANALTEDEGDY-VFAP 530
              +S   P      K     +  +E+ RL    V  + ++ KL +   L  +E  + V A 
Sbjct: 21573 VLSWFPPLDDGGAKIDHYIVQKRETSRLAWTNVASEVQVTKLKVTKLLKGNEYIFRVMAV 21632

Query: 531   DAYNVTLPAKVHVI---------DPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPK 581
             + Y V  P +   +         DPPK        +  VT I  + +   +   G P   
Sbjct: 21633 NKYGVGEPLESEPVLAVNPYGPPDPPK--------NPEVTTITKDSM---VVCWGHPDSD 21681

Query: 582   A-------MWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAG--- 631
                     +  R DKA      +   ++  D    V  + E  +   + I  +N AG   
Sbjct: 21682 GGSEIINYIVERRDKAGQRWI-KCNKKTLTDLRYKVSGLTEGHEYE-FRIMAENAAGISA 21739

Query: 632   EAHASIKVKVVDF---PDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQS 688
              +  S   K  D    P PP  P V +       + W  P YDGGS I GY +E    + 
Sbjct: 21740 PSPTSPFYKACDTVFKPGPPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIALPEE 21799

Query: 689   SRWMRLNFDL-CKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSM-PSRPFVPLAVTSPP 746
               W  +      K T++    + E   Y++RI+A+N+ G+ +P++ P  P     +  P 
Sbjct: 21800 DEWQIVTPPAGLKATSYTITGLTENQEYKIRIYAMNSEGLGEPALVPGTPKAEDRMLPPE 21859

Query: 747   TLLTVDSVTDTT----------VTMRWRPPDHIGAAGLDGYVLEYC-FEGTEDW---IVA 792
               L  D     T          V ++ RP   +  A   G  L+    E T  +   IV 
Sbjct: 21860 IELDADLRKVVTIRACCTLRLFVPIKGRPAPEVKWARDHGESLDKASIESTSSYTLLIVG 21919

Query: 793   NKDLIDKTKF--TITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEII--------E 842
             N +  D  K+  T+         FV V+ ++  G        Q + VKE+         +
Sbjct: 21920 NVNRFDSGKYILTVENSSGSKSAFVNVRVLDTPGPP------QDLKVKEVTKTSVTLTWD 21973

Query: 843   PPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTI 902
             PP +     +K  YI    E+             + +WK D  +           E  + 
Sbjct: 21974 PPLLDGGSKIKN-YIVEKRESTRKAYSTVATNCHKTSWKVDQLQ-----------EGCSY 22021

Query: 903   IFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPP 962
              F   AE  +         +    ETA   ++  +RP PP  + + DV   +V+L+W  P
Sbjct: 22022 YFRVLAENEYG--------IGLPAETAE-SVKASERPLPPGKITLMDVTRNSVSLSWEKP 22072

Query: 963   KDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSE 1022
             + DG + I GY ++   K S +W T       T ATIT L+ G EY FRV ++N  G+S+
Sbjct: 22073 EHDGGSRILGYIVEMQTKGSDKWATCAT-VKVTEATITGLIQGEEYSFRVSAQNEKGISD 22131

Query: 1023  DATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAI-AGYNATLNCSVRGNP 1081
                ++    VIA+D  I              P   + L NT+ + AG +  ++    G P
Sbjct: 22132 PRQLSVP--VIAKDLVI--------------PPAFKLLFNTFTVLAGEDLKVDVPFIGRP 22175

Query: 1082  KPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLG 1133
              P +TW K+ V +    R    S +    L I+     D G Y  K  N  G
Sbjct: 22176 TPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAG 22227



 Score =  133 bits (334), Expect = 1e-30
 Identities = 211/901 (23%), Positives = 358/901 (39%), Gaps = 95/901 (10%)

Query: 279  FAKILDPAYQVDKGGRVRFVVELA-DPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFIN 337
            F K L+ +  V  G   R   ++A  P++ V W++N  E+  S KY         ++ +N
Sbjct: 5425 FVKKLEASKIVKAGDSSRLECKIAGSPEIRVVWFRNEHELPASDKYRMTFIDSVAVIQMN 5484

Query: 338  NCQMTDDSEYYVTA----GDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSED 393
            N    D  ++   A    G   CST++ V+EPP+  +      T    E V LECE+S  
Sbjct: 5485 NLSTEDSGDFICEAQNPAGSTSCSTKVIVKEPPVFSSFPPIVETLKNAE-VSLECELSGT 5543

Query: 394  DA-NVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTG--GQSSAK 450
                V W+K+  ++    K  Y+I  +     + I     +D  EY        G  +  
Sbjct: 5544 PPFEVVWYKDKRQLRSSKK--YKIASKNFHTSIHILNVDTSDIGEYHCKAQNEVGSDTCV 5601

Query: 451  LSVDLK-PLKILTPLTDQTVNLGKEICLKCEI--SENIPGKWTKNGLPV-QESDRLKVVH 506
             +V LK P + ++ L   TV  G+   L+  I  ++ I  +W K    V +ES+ +++  
Sbjct: 5602 CTVKLKEPPRFVSKLNSLTVVAGEPAELQASIEGAQPIFVQWLKEKEEVIRESENIRITF 5661

Query: 507  KGRIHKLVIANALTEDEGDYV--FAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIA 564
               +  L  A A   + G Y+     D       A + V++P  I+    +    +TV  
Sbjct: 5662 VENVATLQFAKAEPANAGKYICQIKNDGGMRENMATLMVLEPAVIV----EKAGPMTVTV 5717

Query: 565  GNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHI 624
            G    LE  ++G P     W +  K ++  S + +   Y   S+L I   ER D+G Y  
Sbjct: 5718 GETCTLECKVAGTPELSVEWYKDGK-LLTSSQKHKFSFYNKISSLRILSVERQDAGTYTF 5776

Query: 625  NLKNEAGEAHASIKVKVVDFPDPPVAPTVTE-------VGDDWCIMNWEPPAYDGGSPI- 676
             ++N  G++  +    VVD  D  V P+ T        V    CI+  +     G SPI 
Sbjct: 5777 QVQNNVGKSSCT---AVVDVSDRAVPPSFTRRLKNTGGVLGASCILECK---VAGSSPIS 5830

Query: 677  LGYFIERKKKQSSRWMRLNF--DLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPS 734
            + +F E+ K  S    +  F  ++C   T +   +           A N  G  +     
Sbjct: 5831 VAWFHEKTKIVSGAKYQTTFSDNVC---TLQLNSLDSSDMGNYTCVAANVAGSDECRAVL 5887

Query: 735  RPFVPLAVTSPPTLLTV---DSVTDTTVTMRWRPPDHI----GAAGL-DGYVLEYCFEGT 786
                P +    P  L V    +VT T+V +R  PP  +    GA  L  G      FE T
Sbjct: 5888 TVQEPPSFVKEPEPLEVLPGKNVTFTSV-IRGTPPFKVNWFRGARELVKGDRCNIYFEDT 5946

Query: 787  -EDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPK 845
              +  + N D+    ++T             V + NA  AS     +  + VKE     K
Sbjct: 5947 VAELELFNIDISQSGEYTC------------VVSNNAGQAS----CTTRLFVKEPAAFLK 5990

Query: 846  IRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQ-INIRNSETDTIIF 904
             R+  H  +      G+++ L   + G     +TWKKDG  I  ++  NI  +E   I+ 
Sbjct: 5991 -RLSDHSVEP-----GKSIILESTYTGTLPISVTWKKDGFNITTSEKCNIVTTEKTCILE 6044

Query: 905  IRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRP-GPPQIVKIEDVWGENVALTWTPPK 963
            I  + +  +G+Y  +++ +   +     +  ++ P    ++  +E   G++V+L     +
Sbjct: 6045 ILNSTKRDAGQYSCEIENEAGRDVCGALVSTLEPPYFVTELEPLEAAVGDSVSLQC---Q 6101

Query: 964  DDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSED 1023
              G   IT  +  K D K         ++    AT+            VF++     S +
Sbjct: 6102 VAGTPEIT-VSWYKGDTKLRPTPEYRTYFTNNVATL------------VFNKVNINDSGE 6148

Query: 1024 ATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKP 1083
             T   E+++    G      V+   +    P F + L +     G   TL C + G+   
Sbjct: 6149 YTCKAENSI----GTASSKTVFRIQERQLPPSFARQLKDIEQTVGLPVTLTCRLNGSAPI 6204

Query: 1084 KITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1143
            ++ W ++ V + DD   +      V TL+I +      G Y C A N LGT     +L  
Sbjct: 6205 QVCWYRDGVLLRDDENLQTSFVDNVATLKILQTDLSHSGQYSCSASNPLGTASSSARLTA 6264

Query: 1144 K 1144
            +
Sbjct: 6265 R 6265



 Score =  132 bits (332), Expect = 2e-30
 Identities = 198/908 (21%), Positives = 342/908 (37%), Gaps = 94/908 (10%)

Query: 274  KKSAAFAKILDPAYQVDKGGRVRFVVELAD-PKLEVKWYKNGQEIRPSTKYIFEHKGCQR 332
            K+ A F + L+P+  + KG   +   ++   P +++ W+ N +EI+ S+K+         
Sbjct: 4296 KEPATFVEKLEPSQLLKKGDATQLACKVTGTPPIKITWFANDREIKESSKHRMSFVESTA 4355

Query: 333  ILFINNCQMTDDSEYYVTA----GDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELEC 388
            +L + +  + D  EY   A    G + CS+ + V+E P   TK+ +         V L  
Sbjct: 4356 VLRLTDVGIEDSGEYMCEAQNEAGSDHCSSIVIVKESPYF-TKEFKPIEVLKEYDVMLLA 4414

Query: 389  EVSEDDA-NVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTG--G 445
            EV+      + WFK+   +  G K  Y+  ++     L I     ADA EY    T   G
Sbjct: 4415 EVAGTPPFEITWFKDNTILRSGRK--YKTFIQDHLVSLQILKFVAADAGEYQCRVTNEVG 4472

Query: 446  QSSAKLSVDLKPLKILTPLTDQTVNL-GKEICLKCEISENIP--GKWTKNGLPVQESDRL 502
             S     V L+         + T +L G     +  +  ++P    W K+   + E D +
Sbjct: 4473 SSICSARVTLREPPSFIKKIESTSSLRGGTAAFQATLKGSLPITVTWLKDSDEITEDDNI 4532

Query: 503  KVVHKGRIHKLVIANALTEDEGDYVFAP--DAYNVTLPAKVHVIDPPKIILDGLDADNTV 560
            ++  +  +  L ++    + +G YV     DA      A + V +P  I  + +  D   
Sbjct: 4533 RMTFENNVASLYLSGIEVKHDGKYVCQAKNDAGIQRCSALLSVKEPATITEEAVSID--- 4589

Query: 561  TVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSG 620
             V  G+   L++  SG     A W +  + +  GS + +       S L I   E+ DSG
Sbjct: 4590 -VTQGDPATLQVKFSGTKEITAKWFKDGQELTLGS-KYKISVTDTVSILKIISTEKKDSG 4647

Query: 621  VYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYF 680
             Y   ++N+ G +    ++ V+D   PP      +  D       +      GS  +   
Sbjct: 4648 EYTFEVQNDVGRSSCKARINVLDLIIPPSFTKKLKKMDSIKGSFIDLECIVAGSHPISIQ 4707

Query: 681  IERKKKQSSRWMRLNFDLCKETTFEPKKMIEGV-AYEVRIFAVNAIGISKPSMPSRPFVP 739
              +  ++ S   +  F     T F     +EG  +      A N  G ++ S        
Sbjct: 4708 WFKDDQEISASEKYKFSFHDNTAFLEISQLEGTDSGTYTCSATNKAGHNQCS------GH 4761

Query: 740  LAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDL--- 796
            L V  PP  +      D     R +    +G               T  W   NK+L   
Sbjct: 4762 LTVKEPPYFVEKPQSQDVNPNTRVQLKALVGGTA----------PMTIKWFKDNKELHSG 4811

Query: 797  ------IDKTKFTI---TGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIR 847
                   D T  ++       TD+  ++  +  N  G +  K     + VKE   P  I+
Sbjct: 4812 AARSVWKDDTSTSLELFAAKATDSGTYI-CQLSNDVGTATSK---ATLFVKE--PPQFIK 4865

Query: 848  IPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQIN-IRNSETDTIIFIR 906
             P       + R G++        G P+  ++W  DG EI   Q + I   +      I 
Sbjct: 4866 KP---SPVLVLRNGQSTTFECQITGTPKIRVSWYLDGNEITAIQKHGISFIDGLATFQIS 4922

Query: 907  KAERSHSGKYDLQVKVDKFVETASIDIQIIDRP------GPPQIVKIEDVWGENVALTWT 960
             A   +SG Y  + + D    + SI++++ + P       P ++VK  DV  E   +T T
Sbjct: 4923 GARVENSGTYVCEARNDAGTASCSIELKVKEPPTFIRELKPVEVVKYSDVELE-CEVTGT 4981

Query: 961  PPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGL 1020
            PP +        +     + +S + +T+ +     +  IT+    +        E  C +
Sbjct: 4982 PPFE------VTWLKNNREIRSSKKYTLTDRVSVFNLHITKCDPSDT------GEYQCIV 5029

Query: 1021 SEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGN 1080
            S +      S  +A                 E P F + + NT  +   +AT   +V G+
Sbjct: 5030 SNEGGSCSCSTRVA---------------LKEPPSFIKKIENTTTVLKSSATFQSTVAGS 5074

Query: 1081 PKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECK 1140
            P   ITW+K+   + +D    +     V TL+IR       G Y C+A N+ G       
Sbjct: 5075 PPISITWLKDDQILDEDDNVYISFVDSVATLQIRSVDNGHSGRYTCQAKNESGVERCYAF 5134

Query: 1141 LEVKVIAQ 1148
            L V+  AQ
Sbjct: 5135 LLVQEPAQ 5142



 Score =  131 bits (329), Expect = 4e-30
 Identities = 135/530 (25%), Positives = 203/530 (38%), Gaps = 77/530 (14%)

Query: 645   PDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNF-DLCKETT 703
             P PP  P V +       ++W  PAYDGGSPI+GY +E K+  S  W+R N     ++T 
Sbjct: 19589 PGPPAFPKVYDTTRSSVSLSWGKPAYDGGSPIIGYLVEVKRADSDNWVRCNLPQNLQKTR 19648

Query: 704   FEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPP----------TLLTVDS 753
             FE   ++E   Y+ R++AVN IG S PS       P  +  PP          TL+    
Sbjct: 19649 FEVTGLMEDTQYQFRVYAVNKIGYSDPSDVPDKHYPKDILIPPEGELDADLRKTLILRAG 19708

Query: 754   VT-DTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAK 812
             VT    V ++ RPP  I                   W   N +L D+    I    TD  
Sbjct: 19709 VTMRLYVPVKGRPPPKI------------------TWSKPNVNLRDRIGLDIKS--TDFD 19748

Query: 813   IFVRVKAVNAAGASE----------PKYYSQPILVKEIIEPP-KIRIPRHLKQT------ 855
              F+R + VN   A +           K Y+  + V +   PP  + +    K +      
Sbjct: 19749 TFLRCENVNKYDAGKYILTLENSCGKKEYTIVVKVLDTPGPPVNVTVKEISKDSAYVTWE 19808

Query: 856   --YIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHS 913
                I      +N V+  Q +     +W     E  K    + N E     F R    +  
Sbjct: 19809 PPIIDGGSPIINYVV--QKRDAERKSWSTVTTECSKTSFRVANLEEGKSYFFRVFAENEY 19866

Query: 914   GKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGY 973
             G  D     D         ++    PGP   +K+  V   + ++ W  P  DG + I GY
Sbjct: 19867 GIGDPGETRDA--------VKASQTPGPVVDLKVRSVSKSSCSIGWKKPHSDGGSRIIGY 19918

Query: 974   TIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVI 1033
              +    +++ +W  V++       +  +L  G EY FRV +EN  G    + +T    V+
Sbjct: 19919 VVDFLTEEN-KWQRVMKSL-SLQYSAKDLTEGKEYTFRVSAENENGEGTPSEIT----VV 19972

Query: 1034  ARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVA 1093
             ARD     + V  D D    P          A    N  L   ++G P P ++W K +  
Sbjct: 19973 ARD-----DVVAPDLDLKGLPDLCY-----LAKENSNFRLKIPIKGKPAPSVSWKKGEDP 20022

Query: 1094  IVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1143
             +  D R  + S+    TL +      D G Y     N  GT E    ++V
Sbjct: 20023 LATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKEGTISIKV 20072



 Score =  130 bits (328), Expect = 5e-30
 Identities = 80/234 (34%), Positives = 120/234 (51%), Gaps = 8/234 (3%)

Query: 297  FVVELADPKLE-VKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEK 355
            F VEL  P ++ V+W KNG  +  + KY    KG    L I NC + D+S Y    G   
Sbjct: 2726 FTVELTHPNVKGVQWIKNGVVLESNEKYAISVKGTIYSLRIKNCAIVDESVYGFRLGRLG 2785

Query: 356  CSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYR 415
             S  L V    + + K+ +D TA     V  E  VS D   VKWF    EI P  K  +R
Sbjct: 2786 ASARLHVET--VKIIKKPKDVTALENATVAFEVSVSHDTVPVKWFHKSVEIKPSDK--HR 2841

Query: 416  IRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEI 475
            +  E K H L+++  + +DA EY+ +   GQ   K  + ++ L I   + +  V   K  
Sbjct: 2842 LVSERKVHKLMLQNISPSDAGEYTAVV--GQLECKAKLFVETLHITKTMKNIEVPETKTA 2899

Query: 476  CLKCEISE-NIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVF 528
              +CE+S  N+P  W KNG+ ++ S++ K+V +G++H+L+I N  TED  +Y F
Sbjct: 2900 SFECEVSHFNVPSMWLKNGVEIEMSEKFKIVVQGKLHQLIIMNTSTEDSAEYTF 2953



 Score =  129 bits (324), Expect = 2e-29
 Identities = 123/461 (26%), Positives = 196/461 (42%), Gaps = 58/461 (12%)

Query: 488   KWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDY--VFAPDAYNVTLPAKVHVID 545
             KWTK G  +  S R  +       +LVI  A   D G Y  V         +  KV VI 
Sbjct: 30169 KWTKEGQDI--SKRAMIATSETHTELVIKEADRGDSGTYDLVLENKCGKKAVYIKVRVIG 30226

Query: 546   PPKIILDGLDADNTVTVIAGNKLRLEIPISGEPP------------------PKAMWSRG 587
              P      L+ D+             + +S  PP                  PKA W   
Sbjct: 30227 SPNSPEGPLEYDDIQV--------RSVRVSWRPPADDGGADILGYILERREVPKAAWYTI 30278

Query: 588   DKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAG-----EAHASIKVKV- 641
             D        R+R       ++LV+   + +    + ++ +N+ G     ++   +  K  
Sbjct: 30279 DS-------RVR------GTSLVVKGLKENVEYHFRVSAENQFGISKPLKSEEPVTPKTP 30325

Query: 642   VDFPDPPV-APTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCK 700
             ++ P+PP   P V +V      ++W  P  DGGS + GY+IERK+  + +W+R N     
Sbjct: 30326 LNPPEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRVTGYYIERKETSTDKWVRHNKTQIT 30385

Query: 701   ETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFV---PLAVTSPPTLLTVDSVTDT 757
              T +    ++    Y+ RI A N +G+S+ S  S P V   P    S P  L + S++  
Sbjct: 30386 TTMYTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCKDPFDKPSQPGELEILSISKD 30445

Query: 758   TVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRV 817
             +VT++W  P+  G   + GY +EY   G   W  +NK+ I   +FTI GL    +   RV
Sbjct: 30446 SVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERIKDKQFTIGGLLEATEYEFRV 30505

Query: 818   KAVNAAGASEPKYYSQPILVKEII-EPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRP 876
              A N  G S P+  +  I  K    E P IR  + +K     ++GEA  L     G+P P
Sbjct: 30506 FAENETGLSRPRRTAMSIKTKLTSGEAPGIR--KEMKDV-TTKLGEAAQLSCQIVGRPLP 30562

Query: 877   ELTWKKDGAEIDKNQINIRNSETDT-IIFIRKAERSHSGKY 916
             ++ W + G E+ +++    +S+  T  + +   E+   G Y
Sbjct: 30563 DIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVY 30603



 Score =  128 bits (322), Expect = 3e-29
 Identities = 199/880 (22%), Positives = 337/880 (38%), Gaps = 84/880 (9%)

Query: 304  PKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTA----GDEKCSTE 359
            P + V W+  G EI    KY          L +N  + +D  +Y   A    G ++CS  
Sbjct: 7709 PPISVSWFHEGNEISSGRKYQTTLTDNTCALTVNMLEESDSGDYTCIATNMAGSDECSAP 7768

Query: 360  LFVREPPIMVTKQLEDTTAYCGERVELECEV-SEDDANVKWFKNGEEIIPGPKSRYRIRV 418
            L VREPP  V K  +      G  V     V      +V WFK   E++PG   R  + +
Sbjct: 7769 LTVREPPSFVQKP-DPMDVLTGTNVTFTSIVKGTPPFSVSWFKGSSELVPG--DRCNVSL 7825

Query: 419  EGKKHILIIEGATKADAAEYS--VMTTGGQSSAKLSVDLK-PLKILTPLTDQTVNLGKEI 475
            E     L +     + + EY+  V    G++S    + +K P K +  L D ++  GK +
Sbjct: 7826 EDSVAELELFDVDTSQSGEYTCIVSNEAGKASCTTHLYIKAPAKFVKRLNDYSIEKGKPL 7885

Query: 476  CLKCEISENIP--GKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDY-VFAPDA 532
             L+   +   P    W KNG+ V  S R  +    +   L I ++  ED G Y  +  +A
Sbjct: 7886 ILEGTFTGTPPISVTWKKNGINVTPSQRCNITTTEKSAILEIPSSTVEDAGQYNCYIENA 7945

Query: 533  YNV-TLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAI 591
                +  A++ +++PP  +         V V  G+   L+  ++G P     W +GD   
Sbjct: 7946 SGKDSCSAQILILEPPYFV----KQLEPVKVSVGDSASLQCQLAGTPEIGVSWYKGDTK- 8000

Query: 592  MEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPP-VA 650
            +  +   +     + +TLV +  + +DSG Y    +N  GE  AS  + V +   PP  +
Sbjct: 8001 LRPTTTYKMHFRNNVATLVFNQVDINDSGEYICKAENSVGEVSASTFLTVQEQKLPPSFS 8060

Query: 651  PTVTEVGDDWCIMNWEPPAYDGGSPI-LGYFIERKKKQSSRWMRLNFDLCKETTFEPKKM 709
              + +V +   +      A  G  PI + ++ + K  + S  ++ +F L    T    K 
Sbjct: 8061 RQLRDVQETVGLPVVFDCAISGSEPISVSWYKDGKPLKDSPNVQTSF-LDNTATLNIFKT 8119

Query: 710  IEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHI 769
               +A +    A N IG              + +S   L+  +        +R  P D +
Sbjct: 8120 DRSLAGQYSCTATNPIG--------------SASSSARLILTEGKNPPFFDIRLAPVDAV 8165

Query: 770  GAAGLDGYVLEYCFEGTE----DWIVANKDLIDKTKFTITGLPTDAKIFV---------- 815
                 D    E    GT+     W   ++++    K+ I+ L   A + V          
Sbjct: 8166 VGESAD---FECHVTGTQPIKVSWAKDSREIRSGGKYQISYLENSAHLTVLKVDKGDSGQ 8222

Query: 816  -RVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKP 874
                AVN  G       +  + +KE + PP     + L +T     G +  L     G  
Sbjct: 8223 YTCYAVNEVGKDS---CTAQLNIKERLIPPS--FTKRLSETVEETEGNSFKLEGRVAGSQ 8277

Query: 875  RPELTWKKDGAEID-KNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDI 933
               + W K+  EI   +   I       ++ +RKA  + +G Y  +V  D      +  I
Sbjct: 8278 PITVAWYKNNIEIQPTSNCEITFKNNTLVLQVRKAGMNDAGLYTCKVSNDAGSALCTSSI 8337

Query: 934  QIIDRPGPPQIVKIEDVWGENVALTWTP-PKDDGNAAITGYTIQKADKKSMEWFTV---I 989
             I +   PP       V+ +++    TP    +G        +Q ++   ++W      I
Sbjct: 8338 VIKEPKKPP-------VFDQHL----TPVTVSEGEYVQLSCHVQGSEPIRIQWLKAGREI 8386

Query: 990  EHYHRTS---ATITELVIGNEYYFRVFSENMCGLSEDA-TMTKESAVIARDGKIYKNPVY 1045
            +   R S   A+ T ++   +       + +C  S  A + T +S V  +D K    P  
Sbjct: 8387 KPSDRCSFSFASGTAVLELRDVAKADSGDYVCKASNVAGSDTTKSKVTIKD-KPAVAPAT 8445

Query: 1046 EDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSN 1105
            +         F     +   +    AT    V G+P P + W K K   ++    R+F +
Sbjct: 8446 KKAAVDGRLFFVSEPQSIRVVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGG-RVFIH 8504

Query: 1106 Q--GVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1143
            Q      LEIR  +  D G Y C A N+ G +E    L+V
Sbjct: 8505 QKGDEAKLEIRDTTKTDSGLYRCVAFNEHGEIESNVNLQV 8544



 Score =  128 bits (322), Expect = 3e-29
 Identities = 101/352 (28%), Positives = 164/352 (46%), Gaps = 15/352 (4%)

Query: 289   VDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYY 348
             V +G    FV EL+  K+ V W+KN  ++  S   +   +G    L +    + D S+  
Sbjct: 11585 VKEGETATFVCELSHEKMHVVWFKNDAKLHTSRTVLISSEGKTHKLEMKEVTLDDISQIK 11644

Query: 349   VTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIP 408
                 +   + +L V E     T +L D TA   + + L+CEVS+ D  VKWFK+GEEI+P
Sbjct: 11645 AQVKELSSTAQLKVLEADPYFTVKLHDKTAVEKDEITLKCEVSK-DVPVKWFKDGEEIVP 11703

Query: 409   GPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQT 468
              PK  Y I+ +G + IL I+ A   D  EY       ++ A ++V+ + +K+  PL    
Sbjct: 11704 SPK--YSIKADGLRRILKIKKADLKDKGEYVCDCGTDKTKANVTVEARLIKVEKPLYGVE 11761

Query: 469   VNLGKEICLKCEISE-NIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYV 527
             V +G+    + E+SE ++ G+W   G P+  S   +++  G+ H L++ N      G+  
Sbjct: 11762 VFVGETAHFEIELSEPDVHGQWKLKGQPLTASPDCEIIEDGKKHILILHNCQLGMTGEVS 11821

Query: 528   FAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRG 587
             F   A N    A + V + P I +  L   + V V   ++ + E  +S E P    W +G
Sbjct: 11822 F--QAANAKSAANLKVKELPLIFITPL---SDVKVFEKDEAKFECEVSRE-PKTFRWLKG 11875

Query: 588   DKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKV 639
              + I  G  R          ++VI  A  +D   Y      EA + H S K+
Sbjct: 11876 TQEI-TGDDRFELIKDGTKHSMVIKSAAFEDEAKYMF----EAEDKHTSGKL 11922



 Score =  127 bits (320), Expect = 5e-29
 Identities = 123/540 (22%), Positives = 217/540 (40%), Gaps = 60/540 (11%)

Query: 622   YHINLKNEAG---EAHASIKVKVVD---FPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSP 675
             Y +  +N AG    +  S  ++  D    P PP  P + + G     + W  P +DGG+P
Sbjct: 26055 YRVYAENAAGLSLPSETSPLIRAEDPVFLPSPPSKPKIVDSGKTTITIAWVKPLFDGGAP 26114

Query: 676   ILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSR 735
             I GY +E KK   + W + +    + T +    +  G  Y  R+ +VN +G S PS  S 
Sbjct: 26115 ITGYTVEYKKSDDTDW-KTSIQSLRGTEYTISGLTTGAEYVFRVKSVNKVGASDPSDSSD 26173

Query: 736   PFVPLAVTSPP----------TLLTVDSVTDT-TVTMRWRPPDHIGAAGLDGYVLEYCFE 784
             P +       P          TL+     + T TV  R RP  ++  +  D  +    + 
Sbjct: 26174 PQIAKEREEEPLFDIDSEMRKTLIVKAGASFTMTVPFRGRPVPNVLWSKPDTDLRTRAYV 26233

Query: 785   GTED----WIVANKDLIDKTKFTIT--GLPTDAKIFVRVKAVNAAGASEPKYYSQPILVK 838
              T D      + N +  D  K+T+T   + + A + + VK ++  G          I V+
Sbjct: 26234 DTTDSRTSLTIENANRNDSGKYTLTIQNVLSAASLTLVVKVLDTPGPPTN------ITVQ 26287

Query: 839   EIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSE 898
             ++ +   +     L        G A       + +   +  W       ++    + N +
Sbjct: 26288 DVTKESAV-----LSWDVPENDGGAPVKNYHIEKREASKKAWVSVTNNCNRLSYKVTNLQ 26342

Query: 899   TDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALT 958
                I + R      SG+ +  V +    ET    ++I ++P PP+ + +  +  ++V+LT
Sbjct: 26343 EGAIYYFRV-----SGENEFGVGIP--AETKE-GVKITEKPSPPEKLGVTSISKDSVSLT 26394

Query: 959   WTPPKDDGNAAITGYTIQKADKKSMEWF--TVIEHYHRTSATITELVIGNEYYFRVFSEN 1016
             W  P+ DG + I  Y ++  +K    W    V +  H   + + E    +EY+FRVF+EN
Sbjct: 26395 WLKPEHDGGSRIVHYVVEALEKGQKNWVKCAVAKSTHHVVSGLRE---NSEYFFRVFAEN 26451

Query: 1017  MCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCS 1076
               GLS+   +            +    + E  +  E  M   P    Y  AG N  ++  
Sbjct: 26452 QAGLSDPREL------------LLPVLIKEQLEPPEIDMKNFPSHTVYVRAGSNLKVDIP 26499

Query: 1077  VRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVE 1136
             + G P PK+T  ++ V +    R+         T+ +++    D G Y   A N  GT +
Sbjct: 26500 ISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADAGRYEITAANSSGTTK 26559



 Score =  125 bits (315), Expect = 2e-28
 Identities = 87/266 (32%), Positives = 123/266 (46%), Gaps = 11/266 (4%)

Query: 272   EEKKSAAFAKIL--DPAYQV---DKGGRVRFVVEL---ADPKLEVKWYKNGQEIRPSTKY 323
             +E  S A  K+L  DP + V   DK    +  + L       + VKW+K+G+EI PS KY
Sbjct: 11648 KELSSTAQLKVLEADPYFTVKLHDKTAVEKDEITLKCEVSKDVPVKWFKDGEEIVPSPKY 11707

Query: 324   IFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGER 383
               +  G +RIL I    + D  EY    G +K    + V    I V K L     + GE 
Sbjct: 11708 SIKADGLRRILKIKKADLKDKGEYVCDCGTDKTKANVTVEARLIKVEKPLYGVEVFVGET 11767

Query: 384   VELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTT 443
                E E+SE D + +W   G+ +   P     I  +GKKHILI+         E S    
Sbjct: 11768 AHFEIELSEPDVHGQWKLKGQPLTASPDC--EIIEDGKKHILILHNCQLGMTGEVSFQAA 11825

Query: 444   GGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCEIS-ENIPGKWTKNGLPVQESDRL 502
               +S+A L V   PL  +TPL+D  V    E   +CE+S E    +W K    +   DR 
Sbjct: 11826 NAKSAANLKVKELPLIFITPLSDVKVFEKDEAKFECEVSREPKTFRWLKGTQEITGDDRF 11885

Query: 503   KVVHKGRIHKLVIANALTEDEGDYVF 528
             +++  G  H +VI +A  EDE  Y+F
Sbjct: 11886 ELIKDGTKHSMVIKSAAFEDEAKYMF 11911



 Score =  123 bits (309), Expect = 9e-28
 Identities = 196/916 (21%), Positives = 335/916 (36%), Gaps = 106/916 (11%)

Query: 278  AFAKILDPAYQVDKGGRVRFVVE---------LADPKLEVKWYKNGQEIRPSTKYIFEHK 328
            A   +L+PA  V+K   ++                P+L  KW+K+G+E+    KY     
Sbjct: 7578 ATLSVLEPATIVEKPESIKVTTGDTCTLECTVAGTPELSTKWFKDGKELTSDNKYKISFF 7637

Query: 329  GCQRILFINNCQMTDDSEYYVTA----GDEKCSTELFV--REPPIMVTKQLEDTTAYCGE 382
                 L I N   +D   Y        G + C+  L V  R  P   T++L++T    G 
Sbjct: 7638 NKVSGLKIINVAPSDSGVYSFEVQNPVGKDSCTASLQVSDRTVPPSFTRKLKETNGLSGS 7697

Query: 383  RVELECEV-SEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVM 441
             V +EC+V      +V WF  G EI  G K  Y+  +      L +    ++D+ +Y+ +
Sbjct: 7698 SVVMECKVYGSPPISVSWFHEGNEISSGRK--YQTTLTDNTCALTVNMLEESDSGDYTCI 7755

Query: 442  TTGGQSSAKLSVDL---KPLKILTPLTDQTVNLGKEICLKCEISENIPGK--WTKNGLPV 496
             T    S + S  L   +P   +       V  G  +     +    P    W K    +
Sbjct: 7756 ATNMAGSDECSAPLTVREPPSFVQKPDPMDVLTGTNVTFTSIVKGTPPFSVSWFKGSSEL 7815

Query: 497  QESDRLKVVHKGRIHKLVIANALTEDEGDY--VFAPDAYNVTLPAKVHVIDPPKIILDGL 554
               DR  V  +  + +L + +  T   G+Y  + + +A   +    +++  P K +    
Sbjct: 7816 VPGDRCNVSLEDSVAELELFDVDTSQSGEYTCIVSNEAGKASCTTHLYIKAPAKFV---- 7871

Query: 555  DADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIA 614
               N  ++  G  L LE   +G PP    W +    +   S R    +   S+ L I  +
Sbjct: 7872 KRLNDYSIEKGKPLILEGTFTGTPPISVTWKKNGINVTP-SQRCNITTTEKSAILEIPSS 7930

Query: 615  ERDDSGVYHINLKNEAGEAHASIKVKVVDFPD--PPVAPTVTEVGDDWCIMNWEPPAYDG 672
              +D+G Y+  ++N +G+   S ++ +++ P     + P    VGD   +          
Sbjct: 7931 TVEDAGQYNCYIENASGKDSCSAQILILEPPYFVKQLEPVKVSVGDSASLQ-----CQLA 7985

Query: 673  GSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSM 732
            G+P +G            W + +  L   TT++           V     N + I+    
Sbjct: 7986 GTPEIGV----------SWYKGDTKLRPTTTYKMH-----FRNNVATLVFNQVDIND--- 8027

Query: 733  PSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPP-------DHIGAAGLDGYVLEYCFEG 785
             S  ++  A  S   +  V + T  TV  +  PP       D     GL   V +    G
Sbjct: 8028 -SGEYICKAENS---VGEVSASTFLTVQEQKLPPSFSRQLRDVQETVGLP-VVFDCAISG 8082

Query: 786  TE----DWIVANKDLID----KTKF-----TITGLPTDAKIFVRVK--AVNAAGASEPKY 830
            +E     W    K L D    +T F     T+    TD  +  +    A N  G++    
Sbjct: 8083 SEPISVSWYKDGKPLKDSPNVQTSFLDNTATLNIFKTDRSLAGQYSCTATNPIGSASS-- 8140

Query: 831  YSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKN 890
             S  +++ E   PP   I           VGE+ +      G    +++W KD  EI   
Sbjct: 8141 -SARLILTEGKNPPFFDIRLAPVDAV---VGESADFECHVTGTQPIKVSWAKDSREIRSG 8196

Query: 891  -QINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIED 949
             +  I   E    + + K ++  SG+Y      +   ++ +  + I +R  PP   K   
Sbjct: 8197 GKYQISYLENSAHLTVLKVDKGDSGQYTCYAVNEVGKDSCTAQLNIKERLIPPSFTK--- 8253

Query: 950  VWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWF-TVIEHYHRTSATITELVIGNEY 1008
                   L+ T  + +GN+      +  +   ++ W+   IE    ++  IT        
Sbjct: 8254 ------RLSETVEETEGNSFKLEGRVAGSQPITVAWYKNNIEIQPTSNCEITFKNNTLVL 8307

Query: 1009 YFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAG 1068
              R    N  GL          + +     + K P        + P+F Q L       G
Sbjct: 8308 QVRKAGMNDAGLYTCKVSNDAGSALCTSSIVIKEP-------KKPPVFDQHLTPVTVSEG 8360

Query: 1069 YNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKA 1128
                L+C V+G+   +I W+K    I    R       G   LE+R  +  D G Y CKA
Sbjct: 8361 EYVQLSCHVQGSEPIRIQWLKAGREIKPSDRCSFSFASGTAVLELRDVAKADSGDYVCKA 8420

Query: 1129 VNDLGTVEIECKLEVK 1144
             N  G+   + K+ +K
Sbjct: 8421 SNVAGSDTTKSKVTIK 8436



 Score =  122 bits (306), Expect = 2e-27
 Identities = 197/849 (23%), Positives = 321/849 (37%), Gaps = 123/849 (14%)

Query: 344   DSEYYVTAGDEKCSTELFVREPPIMVTKQLEDTTAY-CGERVELECEV-SEDDANVKWFK 401
             DS   +TA DE       V  P I +  +  DT     GE   LE +V  +    ++W +
Sbjct: 23609 DSTGPITAKDE-------VELPRISMDPKFRDTIVVNAGETFRLEADVHGKPLPTIEWLR 23661

Query: 402   NGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKIL 461
               +EI     +R  I+    K +LI++ A + D  +Y +  +    S    V++K L   
Sbjct: 23662 GDKEI--EESARCEIKNTDFKALLIVKDAIRIDGGQYILRASNVAGSKSFPVNVKVLDRP 23719

Query: 462   TPLTDQTVNLGKEICLKCEISENIPGKWTKNGLPVQESDRLKVVHKGRIHKL-------- 513
              P  +  V +      KC ++ + P +    G  +       VV K    +L        
Sbjct: 23720 GP-PEGPVQVTGVTSEKCSLTWSPPLQ--DGGSDISHY----VVEKRETSRLAWTVVASE 23772

Query: 514   VIANALTEDE----GDYVF---APDAYNVTLPAK-VHVIDPPKIILDGLDADNTVTVIAG 565
             V+ N+L   +     +YVF   A + Y V  P +   V+     +L G      VT IA 
Sbjct: 23773 VVTNSLKVTKLLEGNEYVFRIMAVNKYGVGEPLESAPVLMKNPFVLPGPPKSLEVTNIAK 23832

Query: 566   NKLRLEIPISGEPPPKAMWSRGDKA--------IMEGSGRIRTESYPDSSTLVIDIAER- 616
             + + +             W+R D          I+E   R        +   + D+  R 
Sbjct: 23833 DSMTV------------CWNRPDSDGGSEIIGYIVEKRDRSGIRWIKCNKRRITDLRLRV 23880

Query: 617   -----DDSGVYHINLKNEAGEAH---ASIKVKVVD---FPDPPVAPTVTEVGDDWCIMNW 665
                  D    + ++ +N AG      A++  K  D    P PP    + +   +   + W
Sbjct: 23881 TGLTEDHEYEFRVSAENAAGVGEPSPATVYYKACDPVFKPGPPTNAHIVDTTKNSITLAW 23940

Query: 666   EPPAYDGGSPILGYFIERKKKQSSRWMRLNFDL-CKETTFEPKKMIEGVAYEVRIFAVNA 724
               P YDGGS ILGY +E  K     W  +      + T FE  K+ E   Y++R+ A+N 
Sbjct: 23941 GKPIYDGGSEILGYVVEICKADEEEWQIVTPQTGLRVTRFEISKLTEHQEYKIRVCALNK 24000

Query: 725   IGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMR------------WRPPDHIGAA 772
             +G+ + +       P      P L  +DS     + +R             RP   I  +
Sbjct: 24001 VGLGEATSVPGTVKPEDKLEAPEL-DLDSELRKGIVVRAGGSARIHIPFKGRPTPEITWS 24059

Query: 773   GLDG-YVLEYCFEGTEDWI---VANKDLIDKTKFTIT--GLPTDAKIFVRVKAVNAAGAS 826
               +G +  +   E   ++    + N D  D  K+ +           FV VK ++  G  
Sbjct: 24060 REEGEFTDKVQIEKGVNYTQLSIDNCDRNDAGKYILKLENSSGSKSAFVTVKVLDTPGPP 24119

Query: 827   EPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAE 886
                   Q + VKE+ +     +    +   I    +  N VI  +   R    +    ++
Sbjct: 24120 ------QNLAVKEVRKDSAFLV---WEPPIIDGGAKVKNYVIDKRESTRK--AYANVSSK 24168

Query: 887   IDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVK 946
               K    + N     I + R    +  G       V   VET    ++  + P PP  V 
Sbjct: 24169 CSKTSFKVENLTEGAIYYFRVMAENEFG-------VGVPVETVDA-VKAAEPPSPPGKVT 24220

Query: 947   IEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGN 1006
             + DV   + +L W  P+ DG + + GY ++   K + +W  V E     +A +T L  G 
Sbjct: 24221 LTDVSQTSASLMWEKPEHDGGSRVLGYVVEMQPKGTEKWSIVAES-KVCNAVVTGLSSGQ 24279

Query: 1007  EYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAI 1066
             EY FRV + N  G S+   +     VIA+D  I              P    P  NTY+I
Sbjct: 24280 EYQFRVKAYNEKGKSDPRVLGVP--VIAKDLTIQ-------------PSLKLPF-NTYSI 24323

Query: 1067  -AGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYC 1125
              AG +  +   V G P+P I+W+K+   +    R  +        L I++ +  D G Y 
Sbjct: 24324 QAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKYT 24383

Query: 1126  CKAVNDLGT 1134
               A N  GT
Sbjct: 24384 VTATNSAGT 24392



 Score =  121 bits (304), Expect = 3e-27
 Identities = 185/870 (21%), Positives = 323/870 (37%), Gaps = 146/870 (16%)

Query: 338   NCQMTDDSEYYVTAGDEKCSTELFVREPPIMVTKQLEDT-TAYCGERVELECEV-SEDDA 395
             N     DS   +TA DE       +  P   +  + +D    + GE   LE ++  +   
Sbjct: 24685 NFSEPSDSSGAITARDE-------IDAPNASLDPKYKDVIVVHAGETFVLEADIRGKPIP 24737

Query: 396   NVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEY--SVMTTGGQSSAKLSV 453
             +V W K+G+E+     +R  I+   +K  L+++   + D  +Y   +   GG  S  ++V
Sbjct: 24738 DVVWSKDGKEL-EETAARMEIKSTIQKTTLVVKDCIRTDGGQYILKLSNVGGTKSIPITV 24796

Query: 454   DLK--------PLKIL------------TPLTDQTVNLGKEICLKCEISENIPGKWTKNG 493
              +         PLK+              PL D   N+   I  K E S      WT+  
Sbjct: 24797 KVLDRPGPPEGPLKVTGVTAEKCYLAWNPPLQDGGANISHYIIEKRETSRL---SWTQVS 24853

Query: 494   LPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVF---APDAYNVTLPAKVHVID----- 545
               VQ  +        ++ KL+  N       +Y+F   A + Y +  P +   +      
Sbjct: 24854 TEVQALNY-------KVTKLLPGN-------EYIFRVMAVNKYGIGEPLESGPVTACNPY 24899

Query: 546   -----PPKIILDGLDADNTVTVIA------GNKLRLEIPISGEPPPKAMWSRGDKAIMEG 594
                  P    +  +  D+ V   A      G ++   I +         W++ +K  +  
Sbjct: 24900 KPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYI-LEKRDKEGVRWTKCNKKTLTD 24958

Query: 595   SGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGE-AHASIKVKVVDF---PDPPVA 650
               R+R     +  +    +A  + +GV         GE +  S+  +  D    P PP  
Sbjct: 24959 L-RLRVTGLTEGHSYEFRVAAENAAGV---------GEPSEPSVFYRACDALYPPGPPSN 25008

Query: 651   PTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETT------F 704
             P VT+       + W  P YDGG+P+ GY +E K+  +  W       C   T      F
Sbjct: 25009 PKVTDTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAADEWTT-----CTPPTGLQGKQF 25063

Query: 705   EPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTL-----------LTVDS 753
                K+ E   Y  RI A+N+ G+ +P+      V      PP +           L   +
Sbjct: 25064 TVTKLKENTEYNFRICAINSEGVGEPATLPGSVVAQERIEPPEIELDADLRKVVVLRASA 25123

Query: 754   VTDTTVTMRWRPPDHIGAAGLDGYVLEYC-FEGTEDW---IVANKDLIDKTKFTIT--GL 807
                  VT++ RP   +     +G + +    E T  +   ++ N    D  ++ +T    
Sbjct: 25124 TLRLFVTIKGRPEPEVKWEKAEGILTDRAQIEVTSSFTMLVIDNVTRFDSGRYNLTLENN 25183

Query: 808   PTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLV 867
                   FV V+ +++  A        P+ +  I E  K  +    +   I    +  N +
Sbjct: 25184 SGSKTAFVNVRVLDSPSA--------PVNLT-IREVKKDSVTLSWEPPLIDGGAKITNYI 25234

Query: 868   IPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVE 927
             +  +   R       +     K    I N +     + R      S +Y + +  +    
Sbjct: 25235 VEKRETTRKAYATITNNCT--KTTFRIENLQEGCSYYFRVLA---SNEYGIGLPAE---- 25285

Query: 928   TASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFT 987
               +  +++ + P PP  V + DV      + W  P+ DG + ITGY ++   K S +W T
Sbjct: 25286 -TTEPVKVSEPPLPPGRVTLVDVTRNTATIKWEKPESDGGSKITGYVVEMQTKGSEKWST 25344

Query: 988   VIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYED 1047
               +      ATI+ L  G EY FRV + N  G S+   +     VIARD +I        
Sbjct: 25345 CTQ-VKTLEATISGLTAGEEYVFRVAAVNEKGRSDPRQLGVP--VIARDIEI-------- 25393

Query: 1048  FDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQG 1107
                   P    P       A     ++   +G P+  + W K+   + +  R  + S++ 
Sbjct: 25394 -----KPSVELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKT 25448

Query: 1108  VCTLEIRKPSPYDGGTYCCKAVNDLGTVEI 1137
             V +L I++ S  D GTY     N  G++ +
Sbjct: 25449 VTSLSIKEASKEDVGTYELCVSNSAGSITV 25478



 Score =  120 bits (302), Expect = 6e-27
 Identities = 142/561 (25%), Positives = 214/561 (38%), Gaps = 83/561 (14%)

Query: 622   YHINLKNEAGEAHASIKVKVVDF------PDPPVAPTVTEVGDDWCIMNWEPPAYDGGSP 675
             + ++ +NE G    S   K V        P PPV P   +   +   + W+PP +DGGS 
Sbjct: 17084 FRVSAENEIGIGDPSPPSKPVFAKDPIAKPSPPVNPEAIDTTCNSVDLTWQPPRHDGGSK 17143

Query: 676   ILGYFIERKKKQSSRWMRLNF--DLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMP 733
             ILGY +E +K     W R N   + C ET ++   + +G  Y+ R+ AVNA G S P+  
Sbjct: 17144 ILGYIVEYQKVGDEEWRRANHTPESCPETKYKVTGLRDGQTYKFRVLAVNAAGESDPAHV 17203

Query: 734   SRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTE----DW 789
               P +      PP L     + D  +        HI     D   L    +G       W
Sbjct: 17204 PEPVLVKDRLEPPEL-----ILDANMARE----QHIKVG--DTLRLSAIIKGVPFPKVTW 17252

Query: 790   IVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAG----ASEPKYYSQPILVKEIIEPPK 845
                ++D   K +  +T  P  +K+ +R  A    G      E    S+ + VK ++   K
Sbjct: 17253 KKEDRDAPTKARIDVT--PVGSKLEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLD-K 17309

Query: 846   IRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKK---DGAEIDKNQINIRNSETD-- 900
                PR L+ + IR              K    LTWK+   DG  +  N +  R       
Sbjct: 17310 PGPPRDLEVSEIR--------------KDSCYLTWKEPLDDGGSVITNYVVERRDVASAQ 17355

Query: 901   -TIIFIRKAERSHSGKY-------------DLQVKVDKFVETASIDIQIIDR---PGPPQ 943
              + +     ++SH  K+             + Q     FVET    I+ +D    PGPP+
Sbjct: 17356 WSPLSATSKKKSHFAKHLNEGNQYLFRVAAENQYGRGPFVETPK-PIKALDPLHPPGPPK 17414

Query: 944   IVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELV 1003
              +   DV    V+L W  P  DG + ITGY ++  ++ + +W    +        +T L 
Sbjct: 17415 DLHHVDVDKTEVSLVWNKPDRDGGSPITGYLVEYQEEGTQDWIK-FKTVTNLECVVTGLQ 17473

Query: 1004  IGNEYYFRVFSENMCGLS-EDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVN 1062
              G  Y FRV +EN+ GL   D T+  E        K+    V  D    E  +       
Sbjct: 17474 QGKTYRFRVKAENIVGLGLPDTTIPIEC-----QEKLVPPSVELDVKLIEGLVVK----- 17523

Query: 1063  TYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGG 1122
                 AG        +RG P P   W  +   I  D  Y + ++     L I+     D G
Sbjct: 17524 ----AGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTG 17579

Query: 1123  TYCCKAVNDLGTVEIECKLEV 1143
              Y     N  G+  +   L V
Sbjct: 17580 EYQITVSNAAGSKTVAVHLTV 17600



 Score =  120 bits (301), Expect = 7e-27
 Identities = 130/513 (25%), Positives = 208/513 (40%), Gaps = 41/513 (7%)

Query: 121  KGKWMDLASKAGKHLQLKETFERHSRVYTFEMQIIKAKDNFAGNYRCEVTYKDKFDSCSF 180
            KG+W+    + GKHL L       S  +   + I   K +  G Y    TYK      S 
Sbjct: 2649 KGEWL----RDGKHLPLTNNIRSESDGHKRRLIIAATKLDDIGEY----TYKVATSKTSA 2700

Query: 181  DLEVH--ESTGTTPNIDIRSAFKRSGEGQEDAGELDFSGLLKRREVKQQEEEPQVDVWEL 238
             L+V   +   T  N+ +          +     +     +K   V +  E+  + V   
Sbjct: 2701 KLKVEAVKIKKTLKNLTVTETQDAVFTVELTHPNVKGVQWIKNGVVLESNEKYAISV--- 2757

Query: 239  LKNAKPSEYEKIAFQYGITDLRGMLKRLKRMRREEKKSAAFAKILDPAYQVD--KGGRVR 296
                K + Y        I D      RL R+    +      KI+     V   +   V 
Sbjct: 2758 ----KGTIYSLRIKNCAIVDESVYGFRLGRLGASARLHVETVKIIKKPKDVTALENATVA 2813

Query: 297  FVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKC 356
            F V ++   + VKW+    EI+PS K+    +     L + N   +D  EY    G  +C
Sbjct: 2814 FEVSVSHDTVPVKWFHKSVEIKPSDKHRLVSERKVHKLMLQNISPSDAGEYTAVVGQLEC 2873

Query: 357  STELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRI 416
              +LFV    + +TK +++      +    ECEVS  +    W KNG EI    K  ++I
Sbjct: 2874 KAKLFVE--TLHITKTMKNIEVPETKTASFECEVSHFNVPSMWLKNGVEIEMSEK--FKI 2929

Query: 417  RVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEIC 476
             V+GK H LII   +  D+AEY+ +    Q SA L+V   P+ I + L D  +N  ++  
Sbjct: 2930 VVQGKLHQLIIMNTSTEDSAEYTFVCGNDQVSATLTV--TPIMITSMLKD--INAEEKDT 2985

Query: 477  LKCEISENIPG---KWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPD-- 531
            +  E++ N  G   KW KNG+ ++ +D+ ++  K   H L I N    D  DY F     
Sbjct: 2986 ITFEVTVNYEGISYKWLKNGVEIKSTDKCQMRTKKLTHSLNIRNVHFGDAADYTFVAGKA 3045

Query: 532  AYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAI 591
                TL  +   I+  K I D       + V+   +   E  +S EP     W + D+  
Sbjct: 3046 TSTATLYVEARHIEFRKHIKD-------IKVLEKKRAMFECEVS-EPDITVQWMKDDQE- 3096

Query: 592  MEGSGRIRTESYPDSSTLVIDIAERDDSGVYHI 624
            ++ + RI+ +       L+I      D+G Y +
Sbjct: 3097 LQITDRIKIQKEKYVHRLLIPSTRMSDAGKYTV 3129



 Score =  120 bits (301), Expect = 7e-27
 Identities = 89/317 (28%), Positives = 143/317 (45%), Gaps = 11/317 (3%)

Query: 281   KILDPAYQVD--KGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINN 338
             K++ P + V+  +    RF  E+++  +   W   G+ +  +     + +G    L ++N
Sbjct: 12108 KLVRPLHSVEVMETETARFETEISEDDIHANWKLKGEALLQTPDCEIKEEGKIHSLVLHN 12167

Query: 339   CQMTDDSEYYVTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVK 398
             C++         A + K S  L V+   I + + L+D T   GE    +CE+S +D  V+
Sbjct: 12168 CRLDQTGGVDFQAANVKSSAHLRVKPRVIGLLRPLKDVTVTAGETATFDCELSYEDIPVE 12227

Query: 399   WFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPL 458
             W+  G+++ P  K     R EGK H L +      DA E  +     ++ A L V   P+
Sbjct: 12228 WYLKGKKLEPSDK--VVPRSEGKVHTLTLRDVKLEDAGEVQLTAKDFKTHANLFVKEPPV 12285

Query: 459   KILTPLTDQTVNLGKEICLKCEIS-ENIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIAN 517
             +   PL DQTV  G    L+CE+S EN   KW KNG  + +S + ++V  GR+ KLVI +
Sbjct: 12286 EFTKPLEDQTVEEGATAVLECEVSRENAKVKWFKNGTEILKSKKYEIVADGRVRKLVIHD 12345

Query: 518   ALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGE 577
                ED   Y    DA +      ++V+ P    L  L     + V      R E  +S E
Sbjct: 12346 CTPEDIKTYTC--DAKDFKTSCNLNVVPPHVEFLRPL---TDLQVREKEMARFECELSRE 12400

Query: 578   PPPKAMWSRGDKAIMEG 594
                K  W +    I +G
Sbjct: 12401 -NAKVKWFKDGAEIKKG 12416



 Score =  119 bits (298), Expect = 2e-26
 Identities = 113/439 (25%), Positives = 181/439 (41%), Gaps = 46/439 (10%)

Query: 621   VYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYF 680
             V  INL      +  S  V  +D  DPP  P V  +  +   + W  P YDGG  + GY 
Sbjct: 20250 VMAINLAGVGKPSLPSEPVVALDPIDPPGKPEVINITRNSVTLIWTEPKYDGGHKLTGYI 20309

Query: 681   IERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIG-ISKPSMPSRPFVP 739
             +E++   S  WM+ N     E  F    ++EG  YE RI A N  G IS PS  +   + 
Sbjct: 20310 VEKRDLPSKSWMKANHVNVPECAFTVTDLVEGGKYEFRIRAKNTAGAISAPSESTETIIC 20369

Query: 740   LAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDK 799
                   PT++   ++ D  +T++      + A  + G  L         W  A KD+   
Sbjct: 20370 KDEYEAPTIVLDPTIKD-GLTIKAGDTIVLNAISILGKPLP-----KSSWSKAGKDIRPS 20423

Query: 800   TKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRR 859
                 IT  PT + + ++      AG       + P   K            H+K T +  
Sbjct: 20424 DITQITSTPTSSMLTIKYATRKDAG-EYTITATNPFGTK----------VEHVKVTVLDV 20472

Query: 860   VGEAVNLVIPFQGKPRPELTWK---KDGAEIDKNQINIRNSETDTIIFIRKAERSHS--- 913
              G    + I      +  LTW    +DG    K+ I +   ET  +++   +E   S   
Sbjct: 20473 PGPPGPVEISNVSAEKATLTWTPPLEDGGSPIKSYI-LEKRETSRLLWTVVSEDIQSCRH 20531

Query: 914   --------GKYDLQVKV----DKFVETASIDIQIIDR---PGPPQIVKIEDVWGENVALT 958
                      +Y  +V       K     S  ++++DR   PGPP+  ++ +V      ++
Sbjct: 20532 VATKLIQGNEYIFRVSAVNHYGKGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTATVS 20591

Query: 959   WTPPKDDGNAAITGYTIQKADKKSMEWFTVIE-HYHRTSATITELVIGNEYYFRVFSENM 1017
             W  P DDG + ITGY +++ +KKS+ W   I+         +T L  G+ Y FRV +EN 
Sbjct: 20592 WKRPVDDGGSEITGYHVERREKKSLRWVRAIKTPVSDLRCKVTGLQEGSTYEFRVSAENR 20651

Query: 1018  CGL-----SEDATMTKESA 1031
              G+     + D+ + K++A
Sbjct: 20652 AGIGPPSEASDSVLMKDAA 20670



 Score =  117 bits (294), Expect = 5e-26
 Identities = 236/1136 (20%), Positives = 404/1136 (35%), Gaps = 174/1136 (15%)

Query: 85   FIEKPQGGTVKVGEDITFIAKVKAEDLLRKPTIKWFKGKWMDLASKAGKHLQLKETFERH 144
            F + P    V  G  +TF + ++     +   +KWFKG   +L      ++ L++     
Sbjct: 6836 FEQTPDSVEVLPGMSLTFTSVIRGTPPFK---VKWFKGS-RELVPGESCNISLED----- 6886

Query: 145  SRVYTFEMQIIKAKDNFAGNYRCEVTYKDKFDSCSFDLEVHESTGTTPNIDIRSAFKRSG 204
               +  E+++ + +   +G+Y C VT      SC+  L V E           +  KR  
Sbjct: 6887 ---FVTELELFEVQPLESGDYSCLVTNDAGSASCTTHLFVKEPA---------TFVKRLA 6934

Query: 205  EGQEDAG-----ELDFSGL-------LKRREVKQQEEEPQVDVWE--LLKNAKPSEYEKI 250
            +   + G     E  ++G        +K   +  Q E   + + E   +     S  E  
Sbjct: 6935 DFSVETGSPIVLEATYTGTPPISVSWIKDEYLISQSERCSITMTEKSTILEILESTIEDY 6994

Query: 251  AFQYGITDLRGMLKRLKRMRREEKKSAAFAKILDPAYQVDKGGRVRFVVEL--------- 301
            A QY           L      +    A   +L+P Y ++    V  V+           
Sbjct: 6995 A-QYSC---------LIENEAGQDICEALVSVLEPPYFIEPLEHVEAVIGEPATLQCKVD 7044

Query: 302  ADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTA----GDEKCS 357
              P++ + WYK   ++R +  Y  + K     L IN    +D  EY   A    G    S
Sbjct: 7045 GTPEIRISWYKEHTKLRSAPAYKMQFKNNVASLVINKVDHSDVGEYSCKADNSVGAVASS 7104

Query: 358  TELFV--REPPIMVTKQLEDTTAYCGERVELECEVS-EDDANVKWFKNGEEIIPGPKSRY 414
              L +  R+ P    ++L+D     G  V  EC ++  +   V W+K+G  ++    +  
Sbjct: 7105 AVLVIKARKLPPFFARKLKDVHETLGFPVAFECRINGSEPLQVSWYKDG--VLLKDDANL 7162

Query: 415  RIRVEGKKHILIIEGATKADAAEYSVMTTG----GQSSAKLSV---------DLKPLKIL 461
            +         L I    ++   +Y+   +       SSAKL +         DLKP+ + 
Sbjct: 7163 QTSFVHNVATLQILQTDQSHIGQYNCSASNPLGTASSSAKLILSEHEVPPFFDLKPVSV- 7221

Query: 462  TPLTDQTVNLGKEICLKCEISENIPGK--WTKNGLPVQESDRLKVVHKGRIHKLVIANAL 519
                   + LG+    KC ++   P K  W K+   ++     K+        L +    
Sbjct: 7222 ------DLALGESGTFKCHVTGTAPIKITWAKDNREIRPGGNYKMTLVENTATLTVLKVG 7275

Query: 520  TEDEGDYV-FAPD-AYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGE 577
              D G Y  +A + A   +  A++ V +PP+ I      + +  V      R E  I G 
Sbjct: 7276 KGDAGQYTCYASNIAGKDSCSAQLGVQEPPRFI---KKLEPSRIVKQDEFTRYECKIGGS 7332

Query: 578  PPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASI 637
            P  K +W + +  I E S + R       + L +     +DSG Y     N AG A +S 
Sbjct: 7333 PEIKVLWYKDETEIQE-SSKFRMSFVDSVAVLEMHNLSVEDSGDYTCEAHNAAGSASSST 7391

Query: 638  KVKVVDFPDPPV-----APTVTEVGDD---WCIMNWEPPAYDGGSPILGYFIERKKKQSS 689
             +KV    +PP+      P  T  G D    C +   PP +      + ++ ++++ +S 
Sbjct: 7392 SLKV---KEPPIFRKKPHPIETLKGADVHLECELQGTPPFH------VSWYKDKRELRSG 7442

Query: 690  RWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFV-------PLAV 742
            +              + K M E     + I  V+A  I +    +   V        +A+
Sbjct: 7443 K--------------KYKIMSENFLTSIHILNVDAADIGEYQCKATNDVGSDTCVGSIAL 7488

Query: 743  TSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVL-----EYCFEGTEDWIVANKDLI 797
             +PP  +   S   T V    +    I  A     V      E   E    WI  +++ I
Sbjct: 7489 KAPPRFVKKLSDISTVVGKEVQLQTTIEGAEPISVVWFKDKGEIVRESDNIWISYSEN-I 7547

Query: 798  DKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKI-RIPRHLKQTY 856
               +F+        K   ++K  N AG  E            ++EP  I   P  +K T 
Sbjct: 7548 ATLQFSRVEPANAGKYTCQIK--NDAGMQE------CFATLSVLEPATIVEKPESIKVT- 7598

Query: 857  IRRVGEAVNLVIPFQGKPRPELTWKKDGAEI-DKNQINIRNSETDTIIFIRKAERSHSGK 915
                G+   L     G P     W KDG E+   N+  I      + + I     S SG 
Sbjct: 7599 ---TGDTCTLECTVAGTPELSTKWFKDGKELTSDNKYKISFFNKVSGLKIINVAPSDSGV 7655

Query: 916  YDLQVKVDKFVETASIDIQIIDRPGPPQIV-KIEDVWGENVALTWTPPKDDGNAAITGYT 974
            Y  +V+     ++ +  +Q+ DR  PP    K+++  G +           G++ +    
Sbjct: 7656 YSFEVQNPVGKDSCTASLQVSDRTVPPSFTRKLKETNGLS-----------GSSVVMECK 7704

Query: 975  IQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESA--V 1032
            +  +   S+ WF      H  +    E+  G +Y     ++N C L+ +     +S    
Sbjct: 7705 VYGSPPISVSWF------HEGN----EISSGRKYQ-TTLTDNTCALTVNMLEESDSGDYT 7753

Query: 1033 IARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKV 1092
                     +         E P F Q       + G N T    V+G P   ++W K   
Sbjct: 7754 CIATNMAGSDECSAPLTVREPPSFVQKPDPMDVLTGTNVTFTSIVKGTPPFSVSWFKGSS 7813

Query: 1093 AIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVKVIAQ 1148
             +V   R  +     V  LE+        G Y C   N+ G       L +K  A+
Sbjct: 7814 ELVPGDRCNVSLEDSVAELELFDVDTSQSGEYTCIVSNEAGKASCTTHLYIKAPAK 7869



 Score =  116 bits (291), Expect = 1e-25
 Identities = 187/859 (21%), Positives = 324/859 (37%), Gaps = 143/859 (16%)

Query: 349   VTAGDEKCSTELFVREPPIMVTKQLEDT-TAYCGERVELECEV-SEDDANVKWFKNGEEI 406
             +TA DE       V  P I +  + +DT   + GE  +++ ++  +    ++W K  +E+
Sbjct: 22532 ITARDE-------VDPPRISMDPKYKDTIVVHAGESFKVDADIYGKPIPTIQWIKGDQEL 22584

Query: 407   IPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTD 466
                  +R  I+       L ++ A + D+  Y +          ++V++K L    P   
Sbjct: 22585 --SNTARLEIKSTDFATSLSVKDAVRVDSGNYILKAKNVAGERSVTVNVKVLDRPGPPEG 22642

Query: 467   QTVNLGKEICLKCEISENIPGKWTKNGLPVQE--SDRLKVVHKGR-----IHKLVIANAL 519
               V  G     KC ++      W     P+Q+  SD +  + + R     +  +V AN  
Sbjct: 22643 PVVISGVT-AEKCTLA------WKP---PLQDGGSDIINYIVERRETSRLVWTVVDANVQ 22692

Query: 520   TED-------EG-DYVF---APDAYNVTLPAKVH--VIDPPKIILDGLDADNTVTVIAGN 566
             T         EG +Y F   A + Y V  P +    V   P ++ D   A    TV   +
Sbjct: 22693 TLSCKVTKLLEGNEYTFRIMAVNKYGVGEPLESEPVVAKNPFVVPDAPKAPEVTTVTKDS 22752

Query: 567   KLRL-EIPISG------------EPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDI 613
              + + E P S                    W+R  K ++ G  R+R          V  +
Sbjct: 22753 MIVVWERPASDGGSEILGYVLEKRDKEGIRWTRCHKRLI-GELRLR----------VTGL 22801

Query: 614   AERDDSGVYHINLKNEAGEAHAS---IKVKVVD---FPDPPVAPTVTEVGDDWCIMNWEP 667
              E  D   + ++ +N AG +  S      K  D    P PP  P V ++      ++W  
Sbjct: 22802 IENHDYE-FRVSAENAAGLSEPSPPSAYQKACDPIYKPGPPNNPKVIDITRSSVFLSWSK 22860

Query: 668   PAYDGGSPILGYFIERKKKQSSRWMRLNFDL-CKETTFEPKKMIEGVAYEVRIFAVNAIG 726
             P YDGG  I GY +E+       W          +T  E +K++E   Y  RI A+N  G
Sbjct: 22861 PIYDGGCEIQGYIVEKCDVSVGEWTMCTPPTGINKTNIEVEKLLEKHEYNFRICAINKAG 22920

Query: 727   ISKPSMPSRPFVPLAVTSPPTL-----------LTVDSVTDTTVTMRWRPPDHIGAAGLD 775
             + + +    P +       P +           +         V ++ RP   +    +D
Sbjct: 22921 VGEHADVPGPIIVEEKLEAPDIDLDLELRKIINIRAGGSLRLFVPIKGRPTPEVKWGKVD 22980

Query: 776   GYVLEYCF----EGTEDWIVANKDLIDKTKFTIT--GLPTDAKIFVRVKAVNAAGASEPK 829
             G + +             ++ N +  D  K+T+T          FV V+ ++    S P 
Sbjct: 22981 GEIRDAAIIDVTSSFTSLVLDNVNRYDSGKYTLTLENSSGTKSAFVTVRVLDTP--SPPV 23038

Query: 830   YYSQPILVKEII----EPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGA 885
                   + K+ +    EPP +     +K   + +                 E T K   A
Sbjct: 23039 NLKVTEITKDSVSITWEPPLLDGGSKIKNYIVEK----------------REATRKSYAA 23082

Query: 886   EID---KNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPP 942
              +    KN   I   +     + R    +  G       +    +TA   I++ + P PP
Sbjct: 23083 VVTNCHKNSWKIDQLQEGCSYYFRVTAENEYG-------IGLPAQTAD-PIKVAEVPQPP 23134

Query: 943   QIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITEL 1002
               + ++DV   +V+L+WT P+ DG + I  Y ++   K S +W +         A IT L
Sbjct: 23135 GKITVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKHSEKW-SECARVKSLQAVITNL 23193

Query: 1003  VIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVN 1062
               G EY FRV + N  G S+  ++     ++A+D  I  +               +P  +
Sbjct: 23194 TQGEEYLFRVVAVNEKGRSDPRSLAVP--IVAKDLVIEPD--------------VKPAFS 23237

Query: 1063  TYAI-AGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDG 1121
             +Y++  G +  +   + G PKP ITW K+ + +    R  +  +  + TL I++    DG
Sbjct: 23238 SYSVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDG 23297

Query: 1122  GTYCCKAVNDLG--TVEIE 1138
             G Y     N +G  T  IE
Sbjct: 23298 GQYGITVANVVGQKTASIE 23316



 Score =  116 bits (290), Expect = 1e-25
 Identities = 241/1144 (21%), Positives = 409/1144 (35%), Gaps = 166/1144 (14%)

Query: 69   GEEQAKQNANSQLSILFIEKPQGGTVKVGEDITFIAKVKAEDLLRKPTIKWFKGKWMDLA 128
            G ++ +     Q    F+++P+   V  G+++TF + ++     +   + WF+G   +L 
Sbjct: 5879 GSDECRAVLTVQEPPSFVKEPEPLEVLPGKNVTFTSVIRGTPPFK---VNWFRGA-RELV 5934

Query: 129  SKAGKHLQLKETFERHSRVYTFEMQIIKAKDNFAGNYRCEVTYKDKFDSCSFDLEVHEST 188
                 ++  ++T          E+++     + +G Y C V+      SC+  L V E  
Sbjct: 5935 KGDRCNIYFEDTVA--------ELELFNIDISQSGEYTCVVSNNAGQASCTTRLFVKEPA 5986

Query: 189  GTTPNIDIRSAFKRSGEGQEDA--GELDFSGLLKRREVKQQEEEP-------QVDVWELL 239
                 +   S         E    G L  S   K+        E        +  + E+L
Sbjct: 5987 AFLKRLSDHSVEPGKSIILESTYTGTLPISVTWKKDGFNITTSEKCNIVTTEKTCILEIL 6046

Query: 240  KNAKPSEYEKIAFQYGITDLRGMLKRLKRMRREEKKSA--AFAKILDPAYQVDK------ 291
             + K     + A QY              +  E  +    A    L+P Y V +      
Sbjct: 6047 NSTK-----RDAGQYSC-----------EIENEAGRDVCGALVSTLEPPYFVTELEPLEA 6090

Query: 292  --GGRVRFVVELAD-PKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYY 348
              G  V    ++A  P++ V WYK   ++RP+ +Y          L  N   + D  EY 
Sbjct: 6091 AVGDSVSLQCQVAGTPEITVSWYKGDTKLRPTPEYRTYFTNNVATLVFNKVNINDSGEYT 6150

Query: 349  VTA------GDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVS-EDDANVKWFK 401
              A         K    +  R+ P    +QL+D     G  V L C ++      V W++
Sbjct: 6151 CKAENSIGTASSKTVFRIQERQLPPSFARQLKDIEQTVGLPVTLTCRLNGSAPIQVCWYR 6210

Query: 402  NGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTG----GQSSAKLSV---- 453
            +G  ++   ++     V+    + I++    + + +YS   +       SSA+L+     
Sbjct: 6211 DG-VLLRDDENLQTSFVDNVATLKILQ-TDLSHSGQYSCSASNPLGTASSSARLTAREPK 6268

Query: 454  -----DLKPLKILTPLTDQTVNLGKEICLKCEISENIPGK--WTKNGLPVQESDRLKVVH 506
                 D+KP+ I        V  G+    +C ++   P +  W+K+   ++      +  
Sbjct: 6269 KSPFFDIKPVSI-------DVIAGESADFECHVTGAQPMRITWSKDNKEIRPGGNYTITC 6321

Query: 507  KGRIHKLVIANALTEDEGDYV--FAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIA 564
             G    L I      D G Y      D       A++ V +PPK +   L+A        
Sbjct: 6322 VGNTPHLRILKVGKGDSGQYTCQATNDVGKDMCSAQLSVKEPPKFV-KKLEASKVAK--Q 6378

Query: 565  GNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHI 624
            G  ++LE  ISG P  K  W R D  + E S +         + L I+ A  +DSG Y  
Sbjct: 6379 GESIQLECKISGSPEIKVSWFRNDSELHE-SWKYNMSFINSVALLTINEASAEDSGDYIC 6437

Query: 625  NLKNEAGEAHASIKVKVVDFPDPPV-----APTVTEVGDD---WCIMNWEPPAYDGGSPI 676
               N  G+A  S  + V     PPV     +P     G D    C ++  PP        
Sbjct: 6438 EAHNGVGDASCSTALTV---KAPPVFTQKPSPVGALKGSDVILQCEISGTPPFE------ 6488

Query: 677  LGYFIERKKKQSSRWMRL---NFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMP 733
            + +  +RK+ ++S+  ++   +FD    T+     +      E    A N +G    S  
Sbjct: 6489 VVWVKDRKQVRNSKKFKITSKHFD----TSLHILNLEASDVGEYHCKATNEVGSDTCSCS 6544

Query: 734  SRPFVP---LAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWI 790
             +   P   +   S  + L  D+V    +   ++P   +        + E     +E+  
Sbjct: 6545 VKFKEPPRFVKKLSDTSTLIGDAVELRAIVEGFQPISVVWLKDRGEVIRE-----SENTR 6599

Query: 791  VANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPK-IRIP 849
            ++  D I   +          K   ++K  N AG  E         V  ++EP + I  P
Sbjct: 6600 ISFIDNIATLQLGSPEASNSGKYICQIK--NDAGMRECS------AVLTVLEPARIIEKP 6651

Query: 850  RHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEI---DKNQINIRNSETDTIIFIR 906
              +  T     G    L     G P     W KDG E+    K+ I   N      + I 
Sbjct: 6652 EPMTVT----TGNPFALECVVTGTPELSAKWFKDGRELSADSKHHITFINKVAS--LKIP 6705

Query: 907  KAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIV-KIEDVWGENVALTWTPPKDD 965
             AE S  G Y  +VK        ++ + + DR  PP  + K++DV   N  L        
Sbjct: 6706 CAEMSDKGLYSFEVKNSVGKSNCTVSVHVSDRIVPPSFIRKLKDV---NAIL-------- 6754

Query: 966  GNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDAT 1025
            G + +    +  +   S+ WF              E+V G +     FSEN+C L+    
Sbjct: 6755 GASVVLECRVSGSAPISVGWF----------QDGNEIVSGPKCQ-SSFSENVCTLNLSLL 6803

Query: 1026 MTKESAVIARDGKIYKNPVYED-----FDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGN 1080
               ++ +      +  N    D         E P F Q   +   + G + T    +RG 
Sbjct: 6804 EPSDTGIYT---CVAANVAGSDECSAVLTVQEPPSFEQTPDSVEVLPGMSLTFTSVIRGT 6860

Query: 1081 PKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECK 1140
            P  K+ W K    +V      +     V  LE+ +  P + G Y C   ND G+      
Sbjct: 6861 PPFKVKWFKGSRELVPGESCNISLEDFVTELELFEVQPLESGDYSCLVTNDAGSASCTTH 6920

Query: 1141 LEVK 1144
            L VK
Sbjct: 6921 LFVK 6924



 Score =  115 bits (287), Expect = 3e-25
 Identities = 101/370 (27%), Positives = 158/370 (42%), Gaps = 34/370 (9%)

Query: 291  KGGRVRFVVELAD-----------------PKLEVKWYKNGQEIRPSTKYIFEHKGCQRI 333
            +G  V FV EL D                   +E KWY N  E++ + KY    +  ++ 
Sbjct: 2263 EGAVVEFVKELQDIEVPESYSGELECIVSPENIEGKWYHNDVELKSNGKYTITSRRGRQN 2322

Query: 334  LFINNCQMTDDSEYYVTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSED 393
            L + +    D  EY      +K + +L ++  PI + + L D     G+ V+LE +VS +
Sbjct: 2323 LTVKDVTKEDQGEYSFVIDGKKTTCKLKMKPRPIAILQGLSDQKVCEGDIVQLEVKVSLE 2382

Query: 394  DANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSV 453
                 W K+G+E+   P  R  I ++ + H+L+IE  TK DA  YS        S    V
Sbjct: 2383 SVEGVWMKDGQEV--QPSDRVHIVIDKQSHMLLIEDMTKEDAGNYSFTIPALGLSTSGRV 2440

Query: 454  DLKPLKILTPLTDQTVNLGKEICLKCEIS--ENIPGKWTKNGLPVQESDRLKVVHKGRIH 511
             +  + ++TPL D  V  G +  L+C++S  +    KW  N   ++  DR++ + KG   
Sbjct: 2441 SVYSVDVITPLKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVKGTKQ 2500

Query: 512  KLVIANALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLE 571
            +LVI      DEG Y              V  I     I+ GL  D T T        +E
Sbjct: 2501 RLVINRTHASDEGPYKLIVGRVETNCNLSVEKIK----IIRGL-RDLTCTETQNVVFEVE 2555

Query: 572  IPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAG 631
            +  SG      +W+  DK I + S + + E++     L +    +DD G Y       AG
Sbjct: 2556 LSHSG---IDVLWNFKDKEI-KPSSKYKIEAHGKIYKLTVLNMMKDDEGKYTF----YAG 2607

Query: 632  EAHASIKVKV 641
            E   S K+ V
Sbjct: 2608 ENMTSGKLTV 2617



 Score =  115 bits (287), Expect = 3e-25
 Identities = 182/792 (22%), Positives = 302/792 (38%), Gaps = 105/792 (13%)

Query: 398   KWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKP 457
             KW  +G EI       Y +  +    +L I+   + D  EY +  +    S  ++V L  
Sbjct: 17543 KWTTDGSEI--KTDEHYTVETDNFSSVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTV 17600

Query: 458   LKILTPLTDQTVNLG---KEICLKCEISENIPGKWTKNGLPVQESDRLK----VVHKGRI 510
             L +  P T     L    + + +  +  ++  G    N + V++ D  K    VV  G  
Sbjct: 17601 LDVPGPPTGPINILDVTPEHMTISWQPPKDDGGSPVINYI-VEKQDTRKDTWGVVSSGSS 17659

Query: 511   H-KLVIANALTEDEGDYVFAPDAYNV---------TLPAKVHVIDPPKIILDGLDADNTV 560
               KL I +   +   +YVF   A N          T     H   PP            V
Sbjct: 17660 KTKLKIPHL--QKGCEYVFRVRAENKIGVGPPLDSTPTVAKHKFSPPSP-----PGKPVV 17712

Query: 561   TVIAGNKLRLE--IPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERD- 617
             T I  N   +   +P S    P   +    + +     R+      D    V  + E + 
Sbjct: 17713 TDITENAATVSWTLPKSDGGSPITGYYMERREVTGKWVRVNKTPIADLKFRVTGLYEGNT 17772

Query: 618   -DSGVYHINLKNEAGEAHASIKVKV---VDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGG 673
              +  V+  NL   +  + +S  +K    +  P PP+ P + +   +   + W  P  DGG
Sbjct: 17773 YEFRVFAENLAGLSKPSPSSDPIKACRPIKPPGPPINPKLKDKSRETADLVWTKPLSDGG 17832

Query: 674   SPILGYFIERKKKQSSRWMRLNFD-LCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSM 732
             SPILGY +E +K  +++W R+N D L ++  F    +IEG  Y  RI A N +G  +P  
Sbjct: 17833 SPILGYVVECQKPGTAQWNRINKDELIRQCAFRVPGLIEGNEYRFRIKAANIVGEGEPRE 17892

Query: 733   PSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVA 792
              +   +   +  PP +  +D      +T+R      I  A + G       E    W   
Sbjct: 17893 LAESVIAKDILHPPEV-ELDVTCRDVITVRVGQTIRI-LARVKGRP-----EPDITWTKE 17945

Query: 793   NKDLI-DKTKFTITGLPTDAKIFVRVKAVNAAGASEPKY---------YSQPILVKEIIE 842
              K L+ +K    I  LP      V ++   A  A   KY         ++Q   +  +++
Sbjct: 17946 GKVLVREKRVDLIQDLPR-----VELQIKEAVRADHGKYIISAKNSSGHAQGSAIVNVLD 18000

Query: 843   PPKIRIPRHLKQTYIRRVG--------------EAVNLVIPFQGKPRPELTWKKDGAEID 888
              P     ++LK T + +                E  N ++ ++ KP  +  W    +++ 
Sbjct: 18001 RPGPC--QNLKVTNVTKENCTISWENPLDNGGSEITNFIVEYR-KPNQK-GWSIVASDVT 18056

Query: 889   KNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETAS--IDIQIIDRPGPPQIVK 946
             K  I       +   F   AE         +V V   +ET +  + I  IDRPG P+ + 
Sbjct: 18057 KRLIKANLLANNEYYFRVCAEN--------KVGVGPTIETKTPILAINPIDRPGEPENLH 18108

Query: 947   IEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGN 1006
             I D     V L W  P  DG +    Y +++  K S +W  V +   + +  + +  + N
Sbjct: 18109 IADKGKTFVYLKWRRPDYDGGSPNLSYHVERRLKGSDDWERVHKGSIKETHYMVDRCVEN 18168

Query: 1007  EYY-FRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYA 1065
             + Y FRV ++N  G S+   +  E  V+  D               + P+    L     
Sbjct: 18169 QIYEFRVQTKNEGGESD--WVKTEEVVVKED--------------LQKPVLDLKLSGVLT 18212

Query: 1066  I-AGYNATLNCSVRGNPKPKITWMKNKVA--IVDDPRYRMFSNQGVCTLEIRKPSPYDGG 1122
             + AG    L   VRG P P++ W K+K A  +   PR ++ +        + K    DGG
Sbjct: 18213 VKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKAKRSDGG 18272

Query: 1123  TYCCKAVNDLGT 1134
              Y   A N  G+
Sbjct: 18273 KYVVTATNTAGS 18284



 Score =  112 bits (281), Expect = 2e-24
 Identities = 184/898 (20%), Positives = 332/898 (36%), Gaps = 146/898 (16%)

Query: 306  LEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEY--YVT--AGDEKCSTELF 361
            +++ W K+ +EIRP   Y          L +      D  +Y  Y +  AG + CS +L 
Sbjct: 7241 IKITWAKDNREIRPGGNYKMTLVENTATLTVLKVGKGDAGQYTCYASNIAGKDSCSAQLG 7300

Query: 362  VREPPIMVTKQLEDTTAYCGERVELECEVS-EDDANVKWFKNGEEIIPGPKSRYRIRVEG 420
            V+EPP  + K          E    EC++    +  V W+K+  EI     S++R+    
Sbjct: 7301 VQEPPRFIKKLEPSRIVKQDEFTRYECKIGGSPEIKVLWYKDETEI--QESSKFRMSFVD 7358

Query: 421  KKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLK----PLKILTPLTDQTVNLGKEIC 476
               +L +   +  D+ +Y+        SA  S  LK    P+    P   +T+  G ++ 
Sbjct: 7359 SVAVLEMHNLSVEDSGDYTCEAHNAAGSASSSTSLKVKEPPIFRKKPHPIETLK-GADVH 7417

Query: 477  LKCEISENIPG--KWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAP--DA 532
            L+CE+    P    W K+   ++   + K++ +  +  + I N    D G+Y      D 
Sbjct: 7418 LECELQGTPPFHVSWYKDKRELRSGKKYKIMSENFLTSIHILNVDAADIGEYQCKATNDV 7477

Query: 533  YNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIM 592
             + T    + +  PP+ +    D    ++ + G +++L+  I G  P   +W +    I+
Sbjct: 7478 GSDTCVGSIALKAPPRFVKKLSD----ISTVVGKEVQLQTTIEGAEPISVVWFKDKGEIV 7533

Query: 593  EGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAG--EAHASIKV----KVVDFPD 646
              S  I      + +TL     E  ++G Y   +KN+AG  E  A++ V     +V+ P+
Sbjct: 7534 RESDNIWISYSENIATLQFSRVEPANAGKYTCQIKNDAGMQECFATLSVLEPATIVEKPE 7593

Query: 647  PPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEP 706
                 ++     D C +         G+P L          S++W +   +L  +  ++ 
Sbjct: 7594 -----SIKVTTGDTCTLE----CTVAGTPEL----------STKWFKDGKELTSDNKYK- 7633

Query: 707  KKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPP 766
                  +++  ++  +  I ++        F         +      V+D TV     PP
Sbjct: 7634 ------ISFFNKVSGLKIINVAPSDSGVYSFEVQNPVGKDSCTASLQVSDRTV-----PP 7682

Query: 767  DHI----GAAGLDG--YVLEYCFEGTE----DWIVANKDLIDKTKFTITGLPTDAKIFVR 816
                      GL G   V+E    G+      W     ++    K+  T       + V 
Sbjct: 7683 SFTRKLKETNGLSGSSVVMECKVYGSPPISVSWFHEGNEISSGRKYQTTLTDNTCALTVN 7742

Query: 817  VK-----------AVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVN 865
            +            A N AG+ E    S P+ V+E   P  ++ P  +        G  V 
Sbjct: 7743 MLEESDSGDYTCIATNMAGSDE---CSAPLTVRE--PPSFVQKPDPMDVL----TGTNVT 7793

Query: 866  LVIPFQGKPRPELTWKKDGAEI---DKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKV 922
                 +G P   ++W K  +E+   D+  +++ +S  +  +F    + S SG+Y   V  
Sbjct: 7794 FTSIVKGTPPFSVSWFKGSSELVPGDRCNVSLEDSVAELELF--DVDTSQSGEYTCIVSN 7851

Query: 923  D----------------KFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDG 966
            +                KFV+  + D  I    G P I++        +++TW   K +G
Sbjct: 7852 EAGKASCTTHLYIKAPAKFVKRLN-DYSI--EKGKPLILEGTFTGTPPISVTW---KKNG 7905

Query: 967  NAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATM 1026
               I     Q+ +  + E   ++E        I    + +   +  + EN  G       
Sbjct: 7906 ---INVTPSQRCNITTTEKSAILE--------IPSSTVEDAGQYNCYIENASG------- 7947

Query: 1027 TKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKIT 1086
                          K+         E P F + L       G +A+L C + G P+  ++
Sbjct: 7948 --------------KDSCSAQILILEPPYFVKQLEPVKVSVGDSASLQCQLAGTPEIGVS 7993

Query: 1087 WMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVK 1144
            W K    +     Y+M     V TL   +    D G Y CKA N +G V     L V+
Sbjct: 7994 WYKGDTKLRPTTTYKMHFRNNVATLVFNQVDINDSGEYICKAENSVGEVSASTFLTVQ 8051



 Score =  112 bits (280), Expect = 2e-24
 Identities = 102/419 (24%), Positives = 166/419 (39%), Gaps = 35/419 (8%)

Query: 744   SPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFT 803
             SP   L  D +   +V + WRPP   G A + GY+LE        W   +   +  T   
Sbjct: 30230 SPEGPLEYDDIQVRSVRVSWRPPADDGGADILGYILERREVPKAAWYTIDSR-VRGTSLV 30288

Query: 804   ITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEA 863
             + GL  + +   RV A N  G S+P    +P+  K  + PP+   P       +     +
Sbjct: 30289 VKGLKENVEYHFRVSAENQFGISKPLKSEEPVTPKTPLNPPE---PPSNPPEVLDVTKSS 30345

Query: 864   VNLVIPFQGKPRPELTWKKDGAEIDKNQIN----IRNSETD-TIIFIRKAERSHSGKYDL 918
             V+L      +P+ +   +  G  I++ + +    +R+++T  T             +Y  
Sbjct: 30346 VSLS---WSRPKDDGGSRVTGYYIERKETSTDKWVRHNKTQITTTMYTVTGLVPDAEYQF 30402

Query: 919   QVKVDKFV---ETASIDIQII-----DRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAI 970
             ++     V   ET+     ++     D+P  P  ++I  +  ++V L W  P+ DG   I
Sbjct: 30403 RIIAQNDVGLSETSPASEPVVCKDPFDKPSQPGELEILSISKDSVTLQWEKPECDGGKEI 30462

Query: 971   TGYTIQKADKKSMEWF-TVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKE 1029
              GY ++        W  +  E       TI  L+   EY FRVF+EN  GLS        
Sbjct: 30463 LGYWVEYRQSGDSAWKKSNKERIKDKQFTIGGLLEATEYEFRVFAENETGLSRPRRTAMS 30522

Query: 1030  SAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMK 1089
                    G              EAP   + + +     G  A L+C + G P P I W +
Sbjct: 30523 IKTKLTSG--------------EAPGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYR 30568

Query: 1090  NKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVKVIAQ 1148
                 ++   +Y+M S+    TL +      D G Y C A N++G VE   KL ++   Q
Sbjct: 30569 FGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQATPQ 30627



 Score =  111 bits (278), Expect = 3e-24
 Identities = 200/932 (21%), Positives = 349/932 (37%), Gaps = 128/932 (13%)

Query: 264  KRLKRMRREEKKSAAFAKILDPAYQVDKGGRVRFVVELAD-PKLEVKWYKNGQEIRPSTK 322
            +R+++    E K+A   K      +V  G   +F  E+   P +  +W+K G+EI  S K
Sbjct: 3442 ERIEQEIEMEMKAAPVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDK 3501

Query: 323  YIFEHKGCQRILFINNCQMTDDSEYYVTAGDE----KCSTELFVRE--PPIMVTKQLEDT 376
                       L I   Q+ D  EY   A +E     C+  L V E  PP  +++  +  
Sbjct: 3502 CSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVTEAYPPTFLSRP-KSL 3560

Query: 377  TAYCGERVELECEVSEDDA-NVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADA 435
            T + G+  +  C V+        W K+G  + P P   +RI     KHIL +   T  D 
Sbjct: 3561 TTFVGKAAKFICTVTGTPVIETIWQKDGAALSPSP--NWRISDAENKHILELSNLTIQDR 3618

Query: 436  AEYSVMTTGGQSS----AKLSVDLKP--LKILTPLTDQTVNLGKEICLKCEISEN--IPG 487
              YS   +    +    A+L +  KP  +K L P+      + K++ L+C++ E+  +  
Sbjct: 3619 GVYSCKASNKFGADICQAELIIIDKPHFIKELEPVQSA---INKKVHLECQVDEDRKVTV 3675

Query: 488  KWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYV--FAPDAYNVTLPAKVHVID 545
             W+K+G  +      K+  + +I  L I  A  +D G YV   + +A + +  A V V +
Sbjct: 3676 TWSKDGQKLPPGKDYKICFEDKIATLEIPLAKLKDSGTYVCTASNEAGSSSCSATVTVRE 3735

Query: 546  PPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPD 605
            PP  +      D +  ++ G   RL   + G P  +  W + +K + E S  +R      
Sbjct: 3736 PPSFV---KKVDPSYLMLPGESARLHCKLKGSPVIQVTWFKNNKELSE-SNTVRMYFVNS 3791

Query: 606  SSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGD----DWC 661
             + L I   + +DSG Y     N+ G    S ++ +    +PP      E  D       
Sbjct: 3792 EAILDITDVKVEDSGSYSCEAVNDVGSDSCSTEIVI---KEPPSFIKTLEPADIVRGTNA 3848

Query: 662  IMNWEPPAYDGGSPI-LGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIF 720
            ++  E     G  P  + +F ++K+ +SS+  RL         F  K ++      + IF
Sbjct: 3849 LLQCE---VSGTGPFEISWFKDKKQIRSSKKYRL---------FSQKSLV-----CLEIF 3891

Query: 721  AVNAIGISKPSMPSRPFVPLA-------VTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAG 773
            + N+  + +        V          +  PPT +              +  D + A G
Sbjct: 3892 SFNSADVGEYECVVANEVGKCGCMATHLLKEPPTFV--------------KKVDDLIALG 3937

Query: 774  LDGYVLEYCFEGTE----DWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAG----A 825
                 L+    G+E     W+   + + +  K  ++     A + +    ++  G     
Sbjct: 3938 GQTVTLQAAVRGSEPISVTWMKGQEVIREDGKIKMSFSNGVAVLIIPDVQISFGGKYTCL 3997

Query: 826  SEPKYYSQPILVKEII-EPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDG 884
            +E +  SQ  + + I+ EP KI     L Q      G+   L     G P  +  W KDG
Sbjct: 3998 AENEAGSQTSVGELIVKEPAKIIERAELIQV---TAGDPATLEYTVAGTPELKPKWYKDG 4054

Query: 885  AEI---DKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGP 941
              +    K +I+ +N+      +   AE   SG+Y  ++  +    +      ++DR   
Sbjct: 4055 RPLVASKKYRISFKNNVAQLKFY--SAELHDSGQYTFEISNEVGSSSCETTFTVLDR--- 4109

Query: 942  PQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITE 1001
                        ++A  +T P  + ++ + G    + D K      +   + +    I  
Sbjct: 4110 ------------DIAPFFTKPLRNVDSVVNGTC--RLDCKIAGSLPMRVSWFKDGKEIA- 4154

Query: 1002 LVIGNEYYFRVFSENMCGLS------EDA---TMTKESAVIARDGKIYKNPVYEDFDFSE 1052
                ++ Y   F E    L        DA   T    ++V ++D               E
Sbjct: 4155 ---ASDRYRIAFVEGTASLEIIRVDMNDAGNFTCRATNSVGSKDSS-------GALIVQE 4204

Query: 1053 APMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLE 1112
             P F     +   + G    L  + +G+    I W K    +V      +       +LE
Sbjct: 4205 PPSFVTKPGSKDVLPGSAVCLKSTFQGSTPLTIRWFKGNKELVSGGSCYITKEALESSLE 4264

Query: 1113 IRKPSPYDGGTYCCKAVNDLGTVEIECKLEVK 1144
            +      D GTY CK  N  G VE    L VK
Sbjct: 4265 LYLVKTSDSGTYTCKVSNVAGGVECSANLFVK 4296



 Score =  111 bits (277), Expect = 4e-24
 Identities = 171/794 (21%), Positives = 305/794 (38%), Gaps = 96/794 (12%)

Query: 381   GERVELECEVSEDDA-NVKWFKNGEEIIPGPKSRYRIRVEGKKHI--LIIEGATKADAAE 437
             G  V+L   +S   A  ++W+K+ +E+    ++   + VE    +  ++I+ A + ++  
Sbjct: 26887 GTSVKLRAGISGKPAPTIEWYKDDKEL----QTNALVCVENTTDLASILIKDADRLNSGC 26942

Query: 438   YSVMTTGGQSSAKLSVDL----KPLKILTPLTDQTVNLGKEICLKCEISENIPGKWTKNG 493
             Y +       SA  ++ +    KP     P+  +TV   K   L    +++   K T   
Sbjct: 26943 YELKLRNAMGSASATIRVQILDKPGPPGGPIEFKTVTAEKITLLWRPPADDGGAKITHYI 27002

Query: 494   LPVQESDRLK-VVHKGRIHKLVIANALTEDEGDYVF---APDAYNVTLPAKVH-VIDPPK 548
             +  +E+ R+   +    + + +I         +Y+F   A + Y +  P +   V+    
Sbjct: 27003 VEKRETSRVVWSMVSEHLEECIITTTKIIKGNEYIFRVRAVNKYGIGEPLESDSVVAKNA 27062

Query: 549   IILDGLDADNTVTVIAGNKLRL----EIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYP 604
              +  G      VT I  N + +     I   G         + DK  + G  ++  E+  
Sbjct: 27063 FVTPGPPGIPEVTKITKNSMTVVWSRPIADGGSDISGYFLEKRDKKSL-GWFKVLKETIR 27121

Query: 605   DSSTLVIDIAERDDSGVYHINLKNEAGE---AHASIKVKVVDFPDPPVAPTVTEVGDDW- 660
             D+   V  + E  D   Y +   N AG+   +  S   K  D  DPP  P    + D   
Sbjct: 27122 DTRQKVTGLTENSDYQ-YRVCAVNAAGQGPFSEPSEFYKAADPIDPPGPPAKIRIADSTK 27180

Query: 661   --CIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNF-DLCKETTFEPKKMIEGVAYEV 717
                 + W  P YDGGS + GY +E ++ +   W  ++     + T +    +  GV Y  
Sbjct: 27181 SSITLGWSKPVYDGGSAVTGYVVEIRQGEEEEWTTVSTKGEVRTTEYVVSNLKPGVNYYF 27240

Query: 718   RIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGY 777
             R+ AVN  G  +P   + P     +   P +       D  V +R      I  AG D  
Sbjct: 27241 RVSAVNCAGQGEPIEMNEPVQAKDILEAPEI-------DLDVALR---TSVIAKAGEDVQ 27290

Query: 778   VLEYCFEG----TEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVN-----------A 822
             VL   F+G    T  W    K+L    +++I    TD+   + +  V             
Sbjct: 27291 VL-IPFKGRPPPTVTWRKDEKNLGSDARYSIEN--TDSSSLLTIPQVTRNDTGKYILTIE 27347

Query: 823   AGASEPKYYSQPILVKEIIEP---PKIRIPRHLKQTYIRRVGE---------AVNLVIPF 870
              G  EPK  S  + VK +  P    K+++ +H+ +  +  + +          +N VI  
Sbjct: 27348 NGVGEPK--SSTVSVKVLDTPAACQKLQV-KHVSRGTVTLLWDPPLIDGGSPIINYVI-- 27402

Query: 871   QGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETAS 930
             + +   + TW     +       + +    T  F R    +  G       + +  ET  
Sbjct: 27403 EKRDATKRTWSVVSHKCSSTSFKLIDLSEKTPFFFRVLAENEIG-------IGEPCETTE 27455

Query: 931   IDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIE 990
               ++  + P P + + ++D    +V L+WT P  DG + IT Y +++  K    W +   
Sbjct: 27456 -PVKAAEVPAPIRDLSMKDSTKTSVILSWTKPDFDGGSVITEYVVERKGKGEQTW-SHAG 27513

Query: 991   HYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDF 1050
                     +++L   +   FRVF++N  GLS+  T+          G I    V E    
Sbjct: 27514 ISKTCEIEVSQLKEQSVLEFRVFAKNEKGLSDPVTI----------GPI---TVKELIIT 27560

Query: 1051  SEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCT 1110
              E  +   P        G+N  L    +G PKP I+W+K+ + + +    R    +   T
Sbjct: 27561 PEVDLSDIPGAQVTVRIGHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKIT 27620

Query: 1111  LEIRKPSPYDGGTY 1124
             L I+      GG Y
Sbjct: 27621 LSIKNAKKEHGGKY 27634



 Score =  110 bits (276), Expect = 6e-24
 Identities = 178/826 (21%), Positives = 314/826 (38%), Gaps = 118/826 (14%)

Query: 377   TAYCGERVELECEVS-EDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADA 435
             T   G  + L+  V  + +  + W K  +E+    K    ++  GK+   +I+   ++D+
Sbjct: 29058 TIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEK--VSLQYTGKRATAVIKFCDRSDS 29115

Query: 436   AEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCEISENIP-----GKWT 490
              +Y++       +  +SV +K L    P    TV+   +   KC ++ ++P      + T
Sbjct: 29116 GKYTLTVKNASGTKAVSVMVKVLDSPGPCGKLTVSRVTQE--KCTLAWSLPQEDGGAEIT 29173

Query: 491   KNGLPVQESDRLK-VVHKGRIHKLVIANALTEDEGDYVF---APDAYNVTLPAKVH---- 542
                +  +E+ RL  V+ +G    L           +Y+F   A + Y   +P +      
Sbjct: 29174 HYIVERRETSRLNWVIVEGECPTLSYVVTRLIKNNEYIFRVRAVNKYGPGVPVESEPIVA 29233

Query: 543   ----VIDPPKIILDGLDADNTVTVI--------AGNKLRLEIPISGEPPPKAMWSRGDKA 590
                  I  P  I + +       +I         GN++   + +         W+R +K 
Sbjct: 29234 RNSFTIPSPPGIPEEVGTGKEHIIIQWTKPESDGGNEISNYL-VDKREKKSLRWTRVNKD 29292

Query: 591   IMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDF-PDPPV 649
              +    R++  S  +       +   + +G       +E  EA   I  +   + P PP 
Sbjct: 29293 YVVYDTRLKVTSLMEGCDYQFRVTAVNAAG------NSEPSEASNFISCREPSYTPGPPS 29346

Query: 650   APTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLC-KETTFEPKK 708
             AP V +       + W  P YDGG+ I+GY +E ++K + +W R++ +   + T F    
Sbjct: 29347 APRVVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDTDQWYRVHTNATIRNTEFTVPD 29406

Query: 709   MIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTT---------- 758
             +  G  Y  R+ AVN  G+S+ S       P+     P L   D +  T           
Sbjct: 29407 LKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEIPDLELADDLKKTVTIRAGASLRL 29466

Query: 759   -VTMRWRPPDHI--GAAGLDGYVLEYCFEGTEDW---IVANKDLIDKTKFTITGLPTDAK 812
              V++  RPP  I     G+D        + TE +   IV   +  D  K+TI        
Sbjct: 29467 MVSVSGRPPPVITWSKQGID-LASRAIIDTTESYSLLIVDKVNRYDAGKYTI-------- 29517

Query: 813   IFVRVKAVNAAGASEPKYYSQPILVKEIIEP---PKIRIPRHLKQTY-----IRRV--GE 862
                  +A N +G       S  +LVK    P   P +++    + +      I  +  G 
Sbjct: 29518 -----EAENQSGKK-----SATVLVKVYDTPGPCPSVKVKEVSRDSVTITWEIPTIDGGA 29567

Query: 863   AVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKV 922
              VN  I  + +      +K    +  K    I      T+ + R    +  G       +
Sbjct: 29568 PVNNYI-VEKREAAMRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYG-------I 29619

Query: 923   DKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKS 982
              +  ET+   + + + P  P  +++ DV    V L W  P  DG + +TGY ++     +
Sbjct: 29620 GEPCETSDA-VLVSEVPLVPAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGT 29678

Query: 983   MEWF-------TVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIAR 1035
               W        TV+EH      T+T L  G +Y FR+ ++N  G+SE       +AV  +
Sbjct: 29679 ERWMKVVTLKPTVLEH------TVTSLNEGEQYLFRIRAQNEKGVSEPRETV--TAVTVQ 29730

Query: 1036  DGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIV 1095
             D ++         D S     T P    +  AG    L   + G P P  +W      + 
Sbjct: 29731 DLRVLPT-----IDLS-----TMPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLR 29780

Query: 1096  DDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKL 1141
             +  R  + ++  V  L IR+ +  D G Y  +  N  GT     K+
Sbjct: 29781 ESERVTVETHTKVAKLTIRETTIRDTGEYTLELKNVTGTTSETIKV 29826



 Score =  110 bits (275), Expect = 8e-24
 Identities = 108/438 (24%), Positives = 170/438 (38%), Gaps = 62/438 (14%)

Query: 727   ISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGT 786
             + KP +P+ P            +  D VT   +T++W PP   G + +  Y+LE      
Sbjct: 20073 VGKPGIPTGP------------IKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDSVN 20120

Query: 787   EDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGA-----SEPKYYSQPILVKEII 841
               W+      + KT F +T L    +   RV A N  G      SEP     P  V +  
Sbjct: 20121 NKWVTC-ASAVQKTTFRVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVPDAP 20179

Query: 842   EPPKIRIPRH----LKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNS 897
              PP I   RH    L  T  ++ G +       + K R  L WK+     +K  I +R+ 
Sbjct: 20180 PPPNIVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKR----ANKTPIRMRDF 20235

Query: 898   ETDTIIFIRKAERSHSGKYDLQVKVDKFVETAS--------IDIQIIDRPGPPQIVKIED 949
             +   +        +   +Y+ +V                  + +  ID PG P+++ I  
Sbjct: 20236 KVTGL--------TEGLEYEFRVMAINLAGVGKPSLPSEPVVALDPIDPPGKPEVINITR 20287

Query: 950   VWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIE-HYHRTSATITELVIGNEY 1008
                 +V L WT PK DG   +TGY ++K D  S  W      +    + T+T+LV G +Y
Sbjct: 20288 ---NSVTLIWTEPKYDGGHKLTGYIVEKRDLPSKSWMKANHVNVPECAFTVTDLVEGGKY 20344

Query: 1009  YFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAI-- 1066
              FR+ ++N  G     + + E+ +I +D            ++    +   P +       
Sbjct: 20345 EFRIRAKNTAGAISAPSESTET-IICKD------------EYEAPTIVLDPTIKDGLTIK 20391

Query: 1067  AGYNATLNC-SVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYC 1125
             AG    LN  S+ G P PK +W K    I      ++ S      L I+  +  D G Y 
Sbjct: 20392 AGDTIVLNAISILGKPLPKSSWSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGEYT 20451

Query: 1126  CKAVNDLGTVEIECKLEV 1143
               A N  GT     K+ V
Sbjct: 20452 ITATNPFGTKVEHVKVTV 20469



 Score =  109 bits (273), Expect = 1e-23
 Identities = 118/440 (26%), Positives = 185/440 (42%), Gaps = 69/440 (15%)

Query: 622   YHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFI 681
             Y +N    +  + AS  +   +  D P  P VT+V      + W  PAYDGGS ++GY I
Sbjct: 28916 YALNAAGVSKASEASRPIMAQNPVDAPGRPEVTDVTRSTVSLIWSAPAYDGGSKVVGYII 28975

Query: 682   ERK---KKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIG-ISKPSMPSRPF 737
             ERK   +    RW++ N+ +  +  F    + EG  YE R+ A NA G ISK S  + P 
Sbjct: 28976 ERKPVSEVGDGRWLKCNYTIVSDNFFTVTALSEGDTYEFRVLAKNAAGVISKGSESTGPV 29035

Query: 738   VPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTED----WIVAN 793
                   +PP       +    VT+R         AG D  VL+    G  +    W   +
Sbjct: 29036 TCRDEYAPPKAELDARLHGDLVTIR---------AGSD-LVLDAAVGGKPEPKIIWTKGD 29085

Query: 794   K--DLIDKTKFTITGLPTDAKIFVRVKA------VNAAGASEPKYYSQPILVKEIIEPPK 845
             K  DL +K     TG    A I    ++      +    AS  K  S  ++VK +  P  
Sbjct: 29086 KELDLCEKVSLQYTGKRATAVIKFCDRSDSGKYTLTVKNASGTKAVS--VMVKVLDSP-- 29141

Query: 846   IRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTW----KKDGAEI--------DKNQIN 893
                            G    L +    + +  L W    +  GAEI        + +++N
Sbjct: 29142 ---------------GPCGKLTVSRVTQEKCTLAWSLPQEDGGAEITHYIVERRETSRLN 29186

Query: 894   --IRNSETDTIIFIRKAERSHSGKYDLQVK-VDKFVETASIDIQ-IIDR-----PGPPQI 944
               I   E  T+ ++       + +Y  +V+ V+K+     ++ + I+ R     P PP I
Sbjct: 29187 WVIVEGECPTLSYV-VTRLIKNNEYIFRVRAVNKYGPGVPVESEPIVARNSFTIPSPPGI 29245

Query: 945   VKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHY--HRTSATITEL 1002
              +      E++ + WT P+ DG   I+ Y + K +KKS+ W  V + Y  + T   +T L
Sbjct: 29246 PEEVGTGKEHIIIQWTKPESDGGNEISNYLVDKREKKSLRWTRVNKDYVVYDTRLKVTSL 29305

Query: 1003  VIGNEYYFRVFSENMCGLSE 1022
             + G +Y FRV + N  G SE
Sbjct: 29306 MEGCDYQFRVTAVNAAGNSE 29325



 Score =  109 bits (272), Expect = 2e-23
 Identities = 92/363 (25%), Positives = 161/363 (44%), Gaps = 18/363 (4%)

Query: 294  RVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGD 353
            R  F  E+++P + V+W K+ QE++ + +   + +     L I + +M+D  +Y V AG 
Sbjct: 3074 RAMFECEVSEPDITVQWMKDDQELQITDRIKIQKEKYVHRLLIPSTRMSDAGKYTVVAGG 3133

Query: 354  EKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSR 413
               + +LFV    + +    ++      +R  +E EV+EDD +  W+K+G EI    + R
Sbjct: 3134 NVSTAKLFVEGRDVRIRSIKKEVQVIEKQRAVVEFEVNEDDVDAHWYKDGIEINFQVQER 3193

Query: 414  YRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDL-KPLKILTPLTDQTVNLG 472
            ++  VE + H + I    ++DA EY+ +    +SS  L V+  +P ++L  L   TV  G
Sbjct: 3194 HKYVVERRIHRMFISETRQSDAGEYTFVAGRNRSSVTLYVNAPEPPQVLQELQPVTVQSG 3253

Query: 473  KEICLKCEISENIPGK--WTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVF-A 529
            K       IS     K  W K    +    + K +H G+ + L++  A  ED   Y   A
Sbjct: 3254 KPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEA 3313

Query: 530  PDAYNVTLPAKVHVIDPPKIILDGLD-----------ADNTVTVIAGNKLRLEIPISGEP 578
             + Y V   +    ++ P+++    +             +TVT   G   R +  +SG  
Sbjct: 3314 KNDYGVATTSASLSVEVPEVVSPDQEMPVYPPAIITPLQDTVT-SEGQPARFQCRVSG-T 3371

Query: 579  PPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIK 638
              K  W   DK I + S   R   + D+  L I  A  +D G Y     N  G+  ++  
Sbjct: 3372 DLKVSWYSKDKKI-KPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTAN 3430

Query: 639  VKV 641
            + +
Sbjct: 3431 LSL 3433



 Score =  108 bits (271), Expect = 2e-23
 Identities = 224/1076 (20%), Positives = 385/1076 (35%), Gaps = 142/1076 (13%)

Query: 116  TIKWFKGKWMDLASKAGKHLQLKETFERHSRVYTFEMQIIKAKDNFAGNYRCEVTYKDKF 175
            +I+WFK      AS+       K  F  H      E+  ++  D+  G Y C  T K   
Sbjct: 4705 SIQWFKDDQEISASE-------KYKFSFHDNTAFLEISQLEGTDS--GTYTCSATNKAGH 4755

Query: 176  DSCSFDLEVHE---------STGTTPNIDIRSAFKRSGEGQ------EDAGELDFSGLLK 220
            + CS  L V E         S    PN  ++      G         +D  EL       
Sbjct: 4756 NQCSGHLTVKEPPYFVEKPQSQDVNPNTRVQLKALVGGTAPMTIKWFKDNKELHSGAA-- 4813

Query: 221  RREVKQQEEEPQVDVWELLKNAKPSEYEKIAFQYGITDLRGMLKRLKRMRREEKKSAAFA 280
             R V + +    ++++        +   +++   G    +  L          K+   F 
Sbjct: 4814 -RSVWKDDTSTSLELFAAKATDSGTYICQLSNDVGTATSKATLF--------VKEPPQFI 4864

Query: 281  KILDPAYQVDKGGRVRFVVELAD-PKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNC 339
            K   P   +  G    F  ++   PK+ V WY +G EI    K+            I+  
Sbjct: 4865 KKPSPVLVLRNGQSTTFECQITGTPKIRVSWYLDGNEITAIQKHGISFIDGLATFQISGA 4924

Query: 340  QMTDDSEYYV----TAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVS-EDD 394
            ++ +   Y       AG   CS EL V+EPP  + ++L+         VELECEV+    
Sbjct: 4925 RVENSGTYVCEARNDAGTASCSIELKVKEPPTFI-RELKPVEVVKYSDVELECEVTGTPP 4983

Query: 395  ANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYS--VMTTGGQSSAKLS 452
              V W KN  EI    K  Y +        L I     +D  EY   V   GG  S    
Sbjct: 4984 FEVTWLKNNREIRSSKK--YTLTDRVSVFNLHITKCDPSDTGEYQCIVSNEGGSCSCSTR 5041

Query: 453  VDLK-PLKILTPLTDQTVNLGKEICLKCEISENIPGK--WTKNGLPVQESDRLKVVHKGR 509
            V LK P   +  + + T  L      +  ++ + P    W K+   + E D + +     
Sbjct: 5042 VALKEPPSFIKKIENTTTVLKSSATFQSTVAGSPPISITWLKDDQILDEDDNVYISFVDS 5101

Query: 510  IHKLVIANALTEDEGDYVF-APDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKL 568
            +  L I +      G Y   A +   V       ++  P  I   ++   +V V   + +
Sbjct: 5102 VATLQIRSVDNGHSGRYTCQAKNESGVERCYAFLLVQEPAQI---VEKAKSVDVTEKDPM 5158

Query: 569  RLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDS-STLVIDIAERDDSGVYHINLK 627
             LE  ++G P  K  W +  K I+    R  + S+ ++ ++  I    + DSG Y   ++
Sbjct: 5159 TLECVVAGTPELKVKWLKDGKQIV--PSRYFSMSFENNVASFRIQSVMKQDSGQYTFKVE 5216

Query: 628  NEAGEAHASIKVKVVDFPDPP-VAPTVTEVGDDWCIMNWEPPAYDGGSPILG-YFIERKK 685
            N+ G +     ++V+D   PP     +T++               G  PI   +F + K+
Sbjct: 5217 NDFGSSSCDAYLRVLDQNIPPSFTKKLTKMDKVLGSSIHMECKVSGSLPISAQWFKDGKE 5276

Query: 686  KQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSP 745
              +S   RL   +C E +      +E    E+   A     +S  +        L V  P
Sbjct: 5277 ISTSAKYRL---VCHERSVS----LEVNNLELEDTANYTCKVSNVAGDDACSGILTVKEP 5329

Query: 746  PTLLT--------VDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLI 797
            P+ L          DS  +    ++  PP  I                   W   + +L+
Sbjct: 5330 PSFLVKPGRQQAIPDSTVEFKAILKGTPPFKI------------------KWFKDDVELV 5371

Query: 798  DKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKE-------IIEPPKIRIPR 850
               K  I GL      F+ + +V+A+   +   +    +  +       + EPPK    +
Sbjct: 5372 SGPKCFI-GLEGSTS-FLNLYSVDASKTGQYTCHVTNDVGSDSCTTMLLVTEPPK--FVK 5427

Query: 851  HLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAER 910
             L+ + I + G++  L     G P   + W ++  E+  +    R +  D++  I+    
Sbjct: 5428 KLEASKIVKAGDSSRLECKIAGSPEIRVVWFRNEHELPASD-KYRMTFIDSVAVIQMNNL 5486

Query: 911  SHSGKYDLQVKVDKFVETASIDIQIIDRPGP-----PQIVKIEDVWGENVA----LTWTP 961
            S     D   +      + S   ++I +  P     P IV  E +    V+    L+ TP
Sbjct: 5487 STEDSGDFICEAQNPAGSTSCSTKVIVKEPPVFSSFPPIV--ETLKNAEVSLECELSGTP 5544

Query: 962  PKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLS 1021
            P +     +  Y  ++  + S ++    +++H TS  I  +   +   +   ++N  G  
Sbjct: 5545 PFE-----VVWYKDKRQLRSSKKYKIASKNFH-TSIHILNVDTSDIGEYHCKAQNEVGSD 5598

Query: 1022 EDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNP 1081
                  K                       E P F   L +   +AG  A L  S+ G  
Sbjct: 5599 TCVCTVK---------------------LKEPPRFVSKLNSLTVVAGEPAELQASIEGAQ 5637

Query: 1082 KPKITWMKNKVAIV-DDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVE 1136
               + W+K K  ++ +    R+   + V TL+  K  P + G Y C+  ND G  E
Sbjct: 5638 PIFVQWLKEKEEVIRESENIRITFVENVATLQFAKAEPANAGKYICQIKNDGGMRE 5693



 Score =  108 bits (271), Expect = 2e-23
 Identities = 200/906 (22%), Positives = 338/906 (37%), Gaps = 120/906 (13%)

Query: 274  KKSAAFAKILDPAYQVDKGGRVRFVVELAD-PKLEVKWYKNGQEIRPSTKYIFEHKGCQR 332
            K+   F + L P  +V K   V    E+   P  EV W KN +EIR S KY    +    
Sbjct: 4952 KEPPTFIRELKPV-EVVKYSDVELECEVTGTPPFEVTWLKNNREIRSSKKYTLTDRVSVF 5010

Query: 333  ILFINNCQMTDDSEYYVTAGDE----KCSTELFVREPPIMVTKQLEDTTAYCGERVELEC 388
             L I  C  +D  EY     +E     CST + ++EPP  + K++E+TT         + 
Sbjct: 5011 NLHITKCDPSDTGEYQCIVSNEGGSCSCSTRVALKEPPSFI-KKIENTTTVLKSSATFQS 5069

Query: 389  EVS-EDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMT---TG 444
             V+     ++ W K+ ++I+    + Y I        L I       +  Y+      +G
Sbjct: 5070 TVAGSPPISITWLKD-DQILDEDDNVY-ISFVDSVATLQIRSVDNGHSGRYTCQAKNESG 5127

Query: 445  GQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCEI--SENIPGKWTKNGLPVQESDRL 502
             +      +  +P +I+       V     + L+C +  +  +  KW K+G  +  S   
Sbjct: 5128 VERCYAFLLVQEPAQIVEKAKSVDVTEKDPMTLECVVAGTPELKVKWLKDGKQIVPSRYF 5187

Query: 503  KVVHKGRIHKLVIANALTEDEGDYVF--APDAYNVTLPAKVHVID---PPKIILDGLDAD 557
             +  +  +    I + + +D G Y F    D  + +  A + V+D   PP         D
Sbjct: 5188 SMSFENNVASFRIQSVMKQDSGQYTFKVENDFGSSSCDAYLRVLDQNIPPSFTKKLTKMD 5247

Query: 558  NTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERD 617
                 + G+ + +E  +SG  P  A W +  K I   S + R   +  S +L ++  E +
Sbjct: 5248 K----VLGSSIHMECKVSGSLPISAQWFKDGKEI-STSAKYRLVCHERSVSLEVNNLELE 5302

Query: 618  DSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPIL 677
            D+  Y   + N AG+   S  + V + P   V P   +   D  +   E  A   G+P  
Sbjct: 5303 DTANYTCKVSNVAGDDACSGILTVKEPPSFLVKPGRQQAIPDSTV---EFKAILKGTPPF 5359

Query: 678  GYFIERKKKQSSRWMRLNFDLCKETTFEPKKMI--EGVAYEVRIFAVNAIGISKPSMPSR 735
                        +W + + +L       PK  I  EG    + +++V+A   SK      
Sbjct: 5360 ----------KIKWFKDDVELVS----GPKCFIGLEGSTSFLNLYSVDA---SKTGQ--- 5399

Query: 736  PFVPLAVTSPPTLLTVDSVTDTTVTMRWRPP--------DHIGAAGLDGYVLEYCFEGTE 787
                  VT+      V S + TT+ +   PP          I  AG D   LE    G+ 
Sbjct: 5400 --YTCHVTN-----DVGSDSCTTMLLVTEPPKFVKKLEASKIVKAG-DSSRLECKIAGSP 5451

Query: 788  D----WIVANKDLIDKTKFTITGLPTDAKIFVR-----------VKAVNAAGASEPKYYS 832
            +    W     +L    K+ +T + + A I +             +A N AG++     S
Sbjct: 5452 EIRVVWFRNEHELPASDKYRMTFIDSVAVIQMNNLSTEDSGDFICEAQNPAGSTS---CS 5508

Query: 833  QPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEI-DKNQ 891
              ++VK   EPP       + +T        V+L     G P  E+ W KD  ++    +
Sbjct: 5509 TKVIVK---EPPVFSSFPPIVETL---KNAEVSLECELSGTPPFEVVWYKDKRQLRSSKK 5562

Query: 892  INIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVW 951
              I +    T I I   + S  G+Y  + + +   +T    +++ +   PP+ V      
Sbjct: 5563 YKIASKNFHTSIHILNVDTSDIGEYHCKAQNEVGSDTCVCTVKLKE---PPRFV------ 5613

Query: 952  GENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFR 1011
             +  +LT       G  A    +I+ A    ++W    E   R S  I            
Sbjct: 5614 SKLNSLTVVA----GEPAELQASIEGAQPIFVQWLKEKEEVIRESENIR----------I 5659

Query: 1012 VFSENMCGL----SEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIA 1067
             F EN+  L    +E A   K    I  DG + +N         E  +  +         
Sbjct: 5660 TFVENVATLQFAKAEPANAGKYICQIKNDGGMREN--MATLMVLEPAVIVEKAGPMTVTV 5717

Query: 1068 GYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCK 1127
            G   TL C V G P+  + W K+   +    +++      + +L I      D GTY  +
Sbjct: 5718 GETCTLECKVAGTPELSVEWYKDGKLLTSSQKHKFSFYNKISSLRILSVERQDAGTYTFQ 5777

Query: 1128 AVNDLG 1133
              N++G
Sbjct: 5778 VQNNVG 5783



 Score =  107 bits (268), Expect = 5e-23
 Identities = 123/468 (26%), Positives = 198/468 (42%), Gaps = 56/468 (11%)

Query: 221  RREVKQQEEE---PQVDVWELLKNAKPSEYEKIAFQYGITDLRGMLKRLKRMRREEKKSA 277
            R + K++ EE     +   EL    K   YE++  +        +L   K +  EEKK+ 
Sbjct: 1998 RSKFKRRTEEGYYEAITAVELKSRKKDESYEELLRK----TKDELLHWTKELTEEEKKAL 2053

Query: 278  AF-AKILDPAYQVDK-----------------------GGRVRFVVELAD-PKLEVKWYK 312
            A   KI  P ++ DK                       G    F V +   P  E +WYK
Sbjct: 2054 AEEGKITIPTFKPDKIELSPSMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYK 2113

Query: 313  NGQEIRPSTK---YIFEHKGCQRILFINNCQMTDDSEYYV----TAGDEKCSTELFVREP 365
            NG +I  S +   Y  E   C+  L I +    D +   V     AG+      L V+  
Sbjct: 2114 NGVKIERSDRIYWYWPEDNVCE--LVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQAK 2171

Query: 366  PIMV-TKQLEDTTAYCGERV-ELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKH 423
             ++  T++L+D  A   + +   ECE SE    VKW+K+G E+  G K  YR+  + K H
Sbjct: 2172 QLITFTQELQDVVAKEKDTMATFECETSEPFVKVKWYKDGMEVHEGDK--YRMHSDRKVH 2229

Query: 424  ILIIEGATKADAAEYS---VMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCE 480
             L I     +DA +YS   V     +++AKL V+   ++ +  L D  V       L+C 
Sbjct: 2230 FLSILTIDTSDAEDYSCVLVEDENVKTTAKLIVEGAVVEFVKELQDIEVPESYSGELECI 2289

Query: 481  IS-ENIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPA 539
            +S ENI GKW  N + ++ + +  +  +     L + +   ED+G+Y F  D    T   
Sbjct: 2290 VSPENIEGKWYHNDVELKSNGKYTITSRRGRQNLTVKDVTKEDQGEYSFVIDGKKTT--C 2347

Query: 540  KVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIR 599
            K+ +   P  IL GL       V  G+ ++LE+ +S E   + +W + D   ++ S R+ 
Sbjct: 2348 KLKMKPRPIAILQGLSDQK---VCEGDIVQLEVKVSLE-SVEGVWMK-DGQEVQPSDRVH 2402

Query: 600  TESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDP 647
                  S  L+I+   ++D+G Y   +          + V  VD   P
Sbjct: 2403 IVIDKQSHMLLIEDMTKEDAGNYSFTIPALGLSTSGRVSVYSVDVITP 2450



 Score =  107 bits (268), Expect = 5e-23
 Identities = 244/1136 (21%), Positives = 420/1136 (36%), Gaps = 179/1136 (15%)

Query: 88   KPQGGTVKVGEDITFIAKVKAEDLLRKP--------------TIKWFKGKWMDLASKAGK 133
            K   G + V E  +F+ K  ++D+L                 TI+WFKG   +L S    
Sbjct: 4194 KDSSGALIVQEPPSFVTKPGSKDVLPGSAVCLKSTFQGSTPLTIRWFKGN-KELVSGGSC 4252

Query: 134  HLQLKETFERHSRVYTFEMQIIKAKDNFAGNYRCEVTYKDKFDSCSFDLEVHESTGTTPN 193
            ++  KE  E      + E+ ++K  D+  G Y C+V+       CS +L V E       
Sbjct: 4253 YIT-KEALES-----SLELYLVKTSDS--GTYTCKVSNVAGGVECSANLFVKEPATFVEK 4304

Query: 194  IDIRSAFKRSGEGQ-----EDAGELDFSGLLKRREVKQQEEEPQ--VDVWELLKNAKPSE 246
            ++     K+    Q          +  +     RE+K+  +     V+   +L+      
Sbjct: 4305 LEPSQLLKKGDATQLACKVTGTPPIKITWFANDREIKESSKHRMSFVESTAVLRLT---- 4360

Query: 247  YEKIAFQYGITDLRGMLKRLKRMRREE--------KKSAAFAKILDPAYQVDKGGRVRFV 298
                    GI D    +   +     +        K+S  F K   P  +V K   V  +
Sbjct: 4361 ------DVGIEDSGEYMCEAQNEAGSDHCSSIVIVKESPYFTKEFKPI-EVLKEYDVMLL 4413

Query: 299  VELAD-PKLEVKWYKNGQEIRPSTKY---IFEHKGCQRIL-FIN------NCQMTDDSEY 347
             E+A  P  E+ W+K+   +R   KY   I +H    +IL F+        C++T++   
Sbjct: 4414 AEVAGTPPFEITWFKDNTILRSGRKYKTFIQDHLVSLQILKFVAADAGEYQCRVTNE--- 4470

Query: 348  YVTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSED-DANVKWFKNGEEI 406
                G   CS  + +REPP  + K++E T++  G     +  +       V W K+ +EI
Sbjct: 4471 ---VGSSICSARVTLREPPSFI-KKIESTSSLRGGTAAFQATLKGSLPITVTWLKDSDEI 4526

Query: 407  IPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGG----QSSAKLSVDLKPLKILT 462
                    R+  E     L + G       +Y           + SA LSV  +P  I  
Sbjct: 4527 TED--DNIRMTFENNVASLYLSGIEVKHDGKYVCQAKNDAGIQRCSALLSVK-EPATITE 4583

Query: 463  PLTDQTVNLGKEICLKCEIS--ENIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALT 520
                  V  G    L+ + S  + I  KW K+G  +    + K+     +  L I +   
Sbjct: 4584 EAVSIDVTQGDPATLQVKFSGTKEITAKWFKDGQELTLGSKYKISVTDTVSILKIISTEK 4643

Query: 521  EDEGDYVFAP--DAYNVTLPAKVHVID---PPKIILDGLDADNTVTVIAGNKLRLEIPIS 575
            +D G+Y F    D    +  A+++V+D   PP         D+    I G+ + LE  ++
Sbjct: 4644 KDSGEYTFEVQNDVGRSSCKARINVLDLIIPPSFTKKLKKMDS----IKGSFIDLECIVA 4699

Query: 576  GEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHA 635
            G  P    W + D+ I   S + +   + +++ L I   E  DSG Y  +  N+AG    
Sbjct: 4700 GSHPISIQWFKDDQEI-SASEKYKFSFHDNTAFLEISQLEGTDSGTYTCSATNKAGHNQC 4758

Query: 636  SIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGS-PILGYFIERKKKQSSRWMRL 694
            S  + V + P     P   +V  +  +   +  A  GG+ P+   + +  K+  S   R 
Sbjct: 4759 SGHLTVKEPPYFVEKPQSQDVNPNTRV---QLKALVGGTAPMTIKWFKDNKELHSGAARS 4815

Query: 695  NFDLCKETTFE--PKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVD 752
             +     T+ E    K  +   Y  ++        SK ++  +   P  +  P  +L + 
Sbjct: 4816 VWKDDTSTSLELFAAKATDSGTYICQLSNDVGTATSKATLFVKE-PPQFIKKPSPVLVLR 4874

Query: 753  SVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDL--IDK-TKFTITGLPT 809
            +   TT   +          G     + +  +G E   +    +  ID    F I+G   
Sbjct: 4875 NGQSTTFECQ--------ITGTPKIRVSWYLDGNEITAIQKHGISFIDGLATFQISGARV 4926

Query: 810  DAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIP 869
            +       +A N AG +         +  ++ EPP     R LK   + +  + V L   
Sbjct: 4927 ENSGTYVCEARNDAGTASCS------IELKVKEPPTFI--RELKPVEVVKYSD-VELECE 4977

Query: 870  FQGKPRPELTWKKDGAEIDKNQINIRNSETDTI----IFIRKAERSHSGKYDLQVKVDKF 925
              G P  E+TW K+  EI  ++   + + TD +    + I K + S +G+Y  Q  V   
Sbjct: 4978 VTGTPPFEVTWLKNNREIRSSK---KYTLTDRVSVFNLHITKCDPSDTGEY--QCIVSNE 5032

Query: 926  VETASIDIQIIDRPGPPQIVKIEDVW---------------GENVALTWTPPKDDGNAAI 970
              + S   ++  +  P  I KIE+                    +++TW   KDD     
Sbjct: 5033 GGSCSCSTRVALKEPPSFIKKIENTTTVLKSSATFQSTVAGSPPISITWL--KDD----- 5085

Query: 971  TGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDAT--MTK 1028
                 Q  D+    + + ++     +  I  +  G+   +   ++N  G+       + +
Sbjct: 5086 -----QILDEDDNVYISFVDSV--ATLQIRSVDNGHSGRYTCQAKNESGVERCYAFLLVQ 5138

Query: 1029 ESAVIARDGKIYKNPVYEDFDFSEA-PMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITW 1087
            E A I    K          D +E  PM                TL C V G P+ K+ W
Sbjct: 5139 EPAQIVEKAK--------SVDVTEKDPM----------------TLECVVAGTPELKVKW 5174

Query: 1088 MKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1143
            +K+   IV    + M     V +  I+     D G Y  K  ND G+   +  L V
Sbjct: 5175 LKDGKQIVPSRYFSMSFENNVASFRIQSVMKQDSGQYTFKVENDFGSSSCDAYLRV 5230



 Score =  106 bits (265), Expect = 1e-22
 Identities = 127/538 (23%), Positives = 203/538 (37%), Gaps = 68/538 (12%)

Query: 645   PDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTF 704
             P PP  P V +       + W+PPA DGGSPI GY +E +++ ++ W R+N      TT 
Sbjct: 15705 PGPPSCPEVKDKTKSSISLGWKPPAKDGGSPIKGYIVEMQEEGTTDWKRVNEPDKLITTC 15764

Query: 705   E--PKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTV--- 759
             E     + E   Y  R+ AVN  G S+PS  +       +   P +       D  V   
Sbjct: 15765 ECVVPNLKELRKYRFRVKAVNEAGESEPSDTTGEIPATDIQEEPEVFIDIGAQDCLVCKA 15824

Query: 760   --------TMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDA 811
                      ++ RP     +   DG   +   +G  D I  +  L      ++  +P   
Sbjct: 15825 GSQIRIPAVIKGRPTPK-SSWEFDGKAKKAMKDGVHD-IPEDAQLETAENSSVIIIPECK 15882

Query: 812   KIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIP-- 869
             +      ++ A   +  K  +  + V ++  PPK      LK + I R    ++  +P  
Sbjct: 15883 RSHTGKYSITAKNKAGQKTANCRVKVMDVPGPPK-----DLKVSDITRGSCRLSWKMPDD 15937

Query: 870   ----------FQGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIR-KAERSHSGKYDL 918
                        + +      W K   +       + +  ++   F R +AE     ++ +
Sbjct: 15938 DGGDRIKGYVIEKRTIDGKAWTKVNPDCGSTTFVVPDLLSEQQYFFRVRAEN----RFGI 15993

Query: 919   QVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQ-- 976
                V+    T + D   I  P PP  +KI  +    V L+W PPK+DG + +T Y ++  
Sbjct: 15994 GPPVETIQRTTARDP--IYPPDPPIKLKIGLITKNTVHLSWKPPKNDGGSPVTHYIVECL 16051

Query: 977   ---KADKKSMEWFTVIEH-YHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAV 1032
                    K   W    +        T+ +LV G EY FRV + N  G+S+ +        
Sbjct: 16052 AWDPTGTKKEAWRQCNKRDVEELQFTVEDLVEGGEYEFRVKAVNAAGVSKPSATVGPCDC 16111

Query: 1033  IARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMK--- 1089
                D      P  +  +F E               G N  +   ++G P P +TW K   
Sbjct: 16112 QRPD----MPPSIDLKEFMEVE------------EGTNVNIVAKIKGVPFPTLTWFKAPP 16155

Query: 1090  ----NKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1143
                 NK  ++ D           CTL I +    D G Y   AVN+LGT   E +L V
Sbjct: 16156 KKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDTGLYTITAVNNLGTASKEMRLNV 16213



 Score =  106 bits (264), Expect = 1e-22
 Identities = 184/906 (20%), Positives = 335/906 (36%), Gaps = 132/906 (14%)

Query: 291  KGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVT 350
            +G   RF   ++   L+V WY   ++I+PS  +          L I      D+  Y   
Sbjct: 3358 EGQPARFQCRVSGTDLKVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFV 3417

Query: 351  A----GDEKCSTELFVREPPI------------------MVTKQLEDTTAYCGERVELEC 388
            A    G    +  L +  P                    ++ +++E      G   +  C
Sbjct: 3418 ASNAVGQVSSTANLSLEAPESILHERIEQEIEMEMKAAPVIKRKIEPLEVALGHLAKFTC 3477

Query: 389  EV-SEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIE--GATKADAAEYSVMTTGG 445
            E+ S  +   +WFK G EI    K   R      K+I  +E       D  EY+   +  
Sbjct: 3478 EIQSAPNVRFQWFKAGREIYESDKCSIR----SSKYISSLEILRTQVVDCGEYTCKASNE 3533

Query: 446  QSSAKLSVDLK-----PLKILTPLTDQTVNLGKEICLKCEISEN--IPGKWTKNGLPVQE 498
              S   +  L      P   L+     T  +GK     C ++    I   W K+G  +  
Sbjct: 3534 YGSVSCTATLTVTEAYPPTFLSRPKSLTTFVGKAAKFICTVTGTPVIETIWQKDGAALSP 3593

Query: 499  SDRLKVVHKGRIHKLVIANALTEDEGDY-VFAPDAYNVTL-PAKVHVIDPPKIILDGLDA 556
            S   ++      H L ++N   +D G Y   A + +   +  A++ +ID P  I +    
Sbjct: 3594 SPNWRISDAENKHILELSNLTIQDRGVYSCKASNKFGADICQAELIIIDKPHFIKELEPV 3653

Query: 557  DNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSG-RIRTESYPDSSTLVIDIAE 615
             + +      K+ LE  +  +      WS+  + +  G   +I  E     +TL I +A+
Sbjct: 3654 QSAI----NKKVHLECQVDEDRKVTVTWSKDGQKLPPGKDYKICFED--KIATLEIPLAK 3707

Query: 616  RDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYD---G 672
              DSG Y     NEAG +  S  V V    +PP    V +V   + ++  E         
Sbjct: 3708 LKDSGTYVCTASNEAGSSSCSATVTV---REPP--SFVKKVDPSYLMLPGESARLHCKLK 3762

Query: 673  GSPIL--GYFIERKKKQSSRWMRLNFDLCKETTFE--PKKMIEGVAYEVRIFAVNAIGIS 728
            GSP++   +F   K+   S  +R+ F +  E   +    K+ +  +Y     AVN +G  
Sbjct: 3763 GSPVIQVTWFKNNKELSESNTVRMYF-VNSEAILDITDVKVEDSGSYSCE--AVNDVGSD 3819

Query: 729  KPSMPSRPFVPLAVTSPP----TLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFE 784
              S        + +  PP    TL   D V  T   ++         +G   + +     
Sbjct: 3820 SCS------TEIVIKEPPSFIKTLEPADIVRGTNALLQCE------VSGTGPFEI----- 3862

Query: 785  GTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPP 844
                W    K +    K+ +      + + + + + N+A   E        +V   +   
Sbjct: 3863 ---SWFKDKKQIRSSKKYRL--FSQKSLVCLEIFSFNSADVGE-----YECVVANEVGKC 3912

Query: 845  KIRIPRHLKQ--TYIRRV-------GEAVNLVIPFQGKPRPELTWKKDGAEI--DKNQIN 893
                   LK+  T++++V       G+ V L    +G     +TW K G E+  +  +I 
Sbjct: 3913 GCMATHLLKEPPTFVKKVDDLIALGGQTVTLQAAVRGSEPISVTWMK-GQEVIREDGKIK 3971

Query: 894  IRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGE 953
            +  S    ++ I   + S  GKY    + +   +T+  ++ + +   P +I++      E
Sbjct: 3972 MSFSNGVAVLIIPDVQISFGGKYTCLAENEAGSQTSVGELIVKE---PAKIIE----RAE 4024

Query: 954  NVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVF 1013
             + +T       G+ A   YT+    +   +W+                ++ ++ Y   F
Sbjct: 4025 LIQVT------AGDPATLEYTVAGTPELKPKWY-----------KDGRPLVASKKYRISF 4067

Query: 1014 SENMCGLSEDATMTKESA-----VIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAG 1068
              N+  L   +    +S      +    G       +   D   AP FT+PL N  ++  
Sbjct: 4068 KNNVAQLKFYSAELHDSGQYTFEISNEVGSSSCETTFTVLDRDIAPFFTKPLRNVDSVVN 4127

Query: 1069 YNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKA 1128
                L+C + G+   +++W K+   I    RYR+   +G  +LEI +    D G + C+A
Sbjct: 4128 GTCRLDCKIAGSLPMRVSWFKDGKEIAASDRYRIAFVEGTASLEIIRVDMNDAGNFTCRA 4187

Query: 1129 VNDLGT 1134
             N +G+
Sbjct: 4188 TNSVGS 4193



 Score =  105 bits (263), Expect = 2e-22
 Identities = 101/375 (26%), Positives = 158/375 (42%), Gaps = 21/375 (5%)

Query: 288  QVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEY 347
            +V +G  V+  V+++   +E  W K+GQE++PS +          +L I +    D   Y
Sbjct: 2366 KVCEGDIVQLEVKVSLESVEGVWMKDGQEVQPSDRVHIVIDKQSHMLLIEDMTKEDAGNY 2425

Query: 348  YVTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDD-ANVKWFKNGEEI 406
              T      ST   V    + V   L+D     G +  LEC+VS  D  +VKW+ N E+I
Sbjct: 2426 SFTIPALGLSTSGRVSVYSVDVITPLKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQI 2485

Query: 407  IPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTD 466
               P  R +  V+G K  L+I     +D   Y ++    +++  LSV+   +KI+  L D
Sbjct: 2486 --KPDDRVQAIVKGTKQRLVINRTHASDEGPYKLIVGRVETNCNLSVE--KIKIIRGLRD 2541

Query: 467  QTVNLGKEICLKCEISEN-IPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGD 525
             T    + +  + E+S + I   W      ++ S + K+   G+I+KL + N + +DEG 
Sbjct: 2542 LTCTETQNVVFEVELSHSGIDVLWNFKDKEIKPSSKYKIEAHGKIYKLTVLNMMKDDEGK 2601

Query: 526  YVF--APDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAM 583
            Y F    +  +  L      I  P         D TV          E+     P  K  
Sbjct: 2602 YTFYAGENMTSGKLTVAGGAISKPL-------TDQTVAESQEAVFECEV---ANPDSKGE 2651

Query: 584  WSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVD 643
            W R  K  +  +  IR+ES      L+I   + DD G Y    K    +  A +KV+ V 
Sbjct: 2652 WLRDGKH-LPLTNNIRSESDGHKRRLIIAATKLDDIGEY--TYKVATSKTSAKLKVEAVK 2708

Query: 644  FPDPPVAPTVTEVGD 658
                    TVTE  D
Sbjct: 2709 IKKTLKNLTVTETQD 2723



 Score =  102 bits (255), Expect = 2e-21
 Identities = 103/389 (26%), Positives = 171/389 (43%), Gaps = 15/389 (3%)

Query: 273   EKKSAAFAKILDPAYQVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHK-GCQ 331
             E+    F K L+    V KG  +    EL + + +V W K+G+ +      I     G  
Sbjct: 11208 EELPVRFVKTLEEEVTVVKGQPLYLSCEL-NKERDVVWRKDGKIVVEKPGRIVPGVIGLM 11266

Query: 332   RILFINNCQMTDDSEYYVT---AGDEKCSTELFVREP-PIMVTKQLEDTTAYCGERVELE 387
             R L IN+   TD   Y VT   A + +CS+ + V E     + K + D            
Sbjct: 11267 RALTINDADDTDAGTYTVTVENANNLECSSCVKVVEVIRDWLVKPIRDQHVKPKGTAIFA 11326

Query: 388   CEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQS 447
             C++++D  N+KWFK  +EI   P  +  I  +G    L I+ A   D AEY+V   G + 
Sbjct: 11327 CDIAKDTPNIKWFKGYDEIPAEPNDKTEILRDGNHLYLKIKNAMPEDIAEYAVEIEGKRY 11386

Query: 448   SAKLSVDLKPLKILTPLTDQTVNLGKEICLKCEISE-NIPGKWTKNGLPVQESDRLKVVH 506
              AKL++  + +++L P+ D T+   +      EISE +IPG+W   G  ++ S   ++  
Sbjct: 11387 PAKLTLGEREVELLKPIEDVTIYEKESASFDAEISEADIPGQWKLKGELLRPSPTCEIKA 11446

Query: 507   KGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGN 566
             +G    L +     +  G+ ++   A N    A   ++   +I LD       VTV    
Sbjct: 11447 EGGKRFLTLHKVKLDQAGEVLY--QALNAITTA---ILTVKEIELDFAVPLKDVTVPERR 11501

Query: 567   KLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINL 626
             + R E  ++ E     +WS+G   I++ S +    +      LVI+ ++ DD GVY   +
Sbjct: 11502 QARFECVLTRE--ANVIWSKGPD-IIKSSDKFDIIADGKKHILVINDSQFDDEGVYTAEV 11558

Query: 627   KNEAGEAHASIKVKVVDFPDPPVAPTVTE 655
             + +   A   +    + F  P    TV E
Sbjct: 11559 EGKKTSARLFVTGIRLKFMSPLEDQTVKE 11587



 Score =  102 bits (254), Expect = 2e-21
 Identities = 85/281 (30%), Positives = 121/281 (43%), Gaps = 16/281 (5%)

Query: 308   VKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTELFVREPPI 367
             V W K    I+ S K+     G + IL IN+ Q  D+  Y      +K S  LFV    +
Sbjct: 11515 VIWSKGPDIIKSSDKFDIIADGKKHILVINDSQFDDEGVYTAEVEGKKTSARLFVTGIRL 11574

Query: 368   MVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILII 427
                  LED T   GE     CE+S +  +V WFKN  ++         I  EGK H L +
Sbjct: 11575 KFMSPLEDQTVKEGETATFVCELSHEKMHVVWFKNDAKL--HTSRTVLISSEGKTHKLEM 11632

Query: 428   EGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCEISENIPG 487
             +  T  D ++         S+A+L V          L D+T     EI LKCE+S+++P 
Sbjct: 11633 KEVTLDDISQIKAQVKELSSTAQLKVLEADPYFTVKLHDKTAVEKDEITLKCEVSKDVPV 11692

Query: 488   KWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYV----FAPDAYNVTLPAKVHV 543
             KW K+G  +  S +  +   G    L I  A  +D+G+YV          NVT+ A++  
Sbjct: 11693 KWFKDGEEIVPSPKYSIKADGLRRILKIKKADLKDKGEYVCDCGTDKTKANVTVEARLIK 11752

Query: 544   IDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMW 584
             ++ P   L G      V V  G     EI +S EP     W
Sbjct: 11753 VEKP---LYG------VEVFVGETAHFEIELS-EPDVHGQW 11783



 Score =  102 bits (254), Expect = 2e-21
 Identities = 174/746 (23%), Positives = 285/746 (38%), Gaps = 121/746 (16%)

Query: 365   PPIMVTKQLEDTTAYCGERVELECEV-SEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKH 423
             P I++ +Q+   T   G+++ +E  V  +     KW K  +E++    S   +       
Sbjct: 18900 PKILMPEQI---TIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTS--SHLAVHKADSSS 18954

Query: 424   ILIIEGATKADAAEYSVMT--TGGQSSAKLSV--------------------DLKPLKIL 461
             ILII+  T+ D+  YS+    + G  + K+ V                    D   L   
Sbjct: 18955 ILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPGPPQPPFDISDIDADACSLSWH 19014

Query: 462   TPLTDQTVNLGKEICLKCEISENIPGKW-TKNGLPVQESDRLKVVHKGRIH--------K 512
              PL D   N+   I  KC++S    G W T      + S R+  +  G+ +        +
Sbjct: 19015 IPLEDGGSNITNYIVEKCDVSR---GDWVTALASVTKTSCRVGKLIPGQEYIFRVRAENR 19071

Query: 513   LVIANALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKIIL--DGLDADNTVTVIAGNKLRL 570
               I+  LT  +    F     +    A+V  ++   I +  D  D+D    +I       
Sbjct: 19072 FGISEPLTSPKMVAQFPFGVPSEPKNARVTKVNKDCIFVAWDRPDSDGGSPIIG------ 19125

Query: 571   EIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEA 630
                I  +     +W + +  +      +R+  YP +   +++  E      + I   N+A
Sbjct: 19126 -YLIERKERNSLLWVKANDTL------VRSTEYPCAG--LVEGLEYS----FRIYALNKA 19172

Query: 631   GEAHASIKVKVVDFP---DPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQ 687
             G +  S   + V      DPP  P V +V      + W  P +DGGS I+GYF+E  K  
Sbjct: 19173 GSSPPSKPTEYVTARMPVDPPGKPEVIDVTKSTVSLIWARPKHDGGSKIIGYFVEACKLP 19232

Query: 688   SSRWMRLNF--DLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSP 745
               +W+R N       +  +    + E   Y+ R  A  A+ IS PS PS P   LA   P
Sbjct: 19233 GDKWVRCNTAPHQIPQEEYTATGLEEKAQYQFRAIARTAVNISPPSEPSDPVTILAENVP 19292

Query: 746   P---------TLLTVDSVT----DTTV------TMRWRPPDHI--GAAGLDGYVLEYCFE 784
             P         +LLTV + T    D TV      T+ W+    +   A G+    ++    
Sbjct: 19293 PRIDLSVAMKSLLTVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIK-MAMQRNLC 19351

Query: 785   GTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEP----KYYSQPILVKEI 840
               E + V  KD  D T  T           +++K ++  G        K YS   ++   
Sbjct: 19352 TLELFSVNRKDSGDYT-ITAENSSGSKSATIKLKVLDKPGPPASVKINKMYSDRAMLSW- 19409

Query: 841   IEPPKIRIPRHLKQTYIRRVG-EAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSET 899
              EPP            +   G E  N ++  +   RP   W +  A +     ++     
Sbjct: 19410 -EPP------------LEDGGSEITNYIVDKRETSRPN--WAQVSATVPITSCSVEKLIE 19454

Query: 900   DTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTW 959
                   R    +  G  D       F E A I     D PG      I ++  +++ ++W
Sbjct: 19455 GHEYQFRICAENKYGVGD-----PVFTEPA-IAKNPYDPPGRCDPPVISNITKDHMTVSW 19508

Query: 960   TPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATI--TELVIGNEYYFRVFSENM 1017
              PP DDG + ITGY ++K + +++ W T +        T+  T L  G EY FRV + N 
Sbjct: 19509 KPPADDGGSPITGYLLEKRETQAVNW-TKVNRKPIIERTLKATGLQEGTEYEFRVTAINK 19567

Query: 1018  CGLSEDATMTKESAVIARDGKIYKNP 1043
              G  + +  +K  A  ARD +    P
Sbjct: 19568 AGPGKPSDASK--AAYARDPQYPPGP 19591



 Score =  101 bits (251), Expect = 5e-21
 Identities = 123/553 (22%), Positives = 204/553 (36%), Gaps = 63/553 (11%)

Query: 622   YHINLKNEAGEAHASIKVKVV---DFPDPPVAPTVTEVGDDW---CIMNWEPPAYDGGSP 675
             + +  +NE G    S+  + V   D  +PP  PT   V D       + W  P YDGG+P
Sbjct: 18468 FRVKAENEIGIGEPSLPSRPVVAKDPIEPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAP 18527

Query: 676   ILGYFIERKKKQSSR-----WMRLNFDL-CKETTFEPKKMIEGVAYEVRIFAVNAIGISK 729
             I+GY +E + K +       W R N         F    + E   YE R+ A N +GI +
Sbjct: 18528 IIGYVVEMRPKIADASPDEGWKRCNAAAQLVRKEFTVTSLDENQEYEFRVCAQNQVGIGR 18587

Query: 730   PSMPSRPFVPLAVTSPPTLLTVDSVTDTTVT-----------MRWRPPDHIG--AAGLDG 776
             P+       P  +  PP +    S+    +            +R RP   +     G+D 
Sbjct: 18588 PAELKEAIKPKEILEPPEIDLDASMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDN 18647

Query: 777   YVLEYCFEGTEDW---IVANKDLIDKTKFTITGL-PTDAK-IFVRVKAVNAAGASEPKYY 831
              V +   +  +     ++ N    D  K+++T + P   K +FV V+ ++  G       
Sbjct: 18648 VVRKGQVDLVDTMAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFVNVRVLDTPG------- 18700

Query: 832   SQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQ 891
               P+   ++ +  K     H+        G +       + +     TW     E+ K  
Sbjct: 18701 --PVSDLKVSDVTKTSC--HVSWAPPENDGGSQVTHYIVEKREADRKTWSTVTPEVKKTS 18756

Query: 892   INIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVW 951
              ++ N       + R    +  G       V   V    +    +  P PP+ +++ ++ 
Sbjct: 18757 FHVTNLVPGNEYYFRVTAVNEYGP-----GVPTDVPKPVLASDPLSEPDPPRKLEVTEMT 18811

Query: 952   GENVALTWTPPKDDGNAAITGY-TIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYF 1010
               +  L W PP  DG A I GY T  + +++  + +T        S  +T L  G +Y F
Sbjct: 18812 KNSATLAWLPPLRDGGAKIDGYITSYREEEQPADRWTEYSVVKDLSLVVTGLKEGKKYKF 18871

Query: 1011  RVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYN 1070
             RV + N  G+S           + R+ +     VYE  +    P    P   T   AG  
Sbjct: 18872 RVAARNAVGVS-----------LPREAE----GVYEAKEQLLPPKILMPEQITIK-AGKK 18915

Query: 1071  ATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVN 1130
               +   V G P P   W K +  +V      +        L I+  +  D G Y   A N
Sbjct: 18916 LRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGYYSLTAEN 18975

Query: 1131  DLGTVEIECKLEV 1143
               GT   + K+ V
Sbjct: 18976 SSGTDTQKIKVVV 18988



 Score =  100 bits (249), Expect = 8e-21
 Identities = 93/398 (23%), Positives = 157/398 (39%), Gaps = 40/398 (10%)

Query: 753   SVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAK 812
             +VT   +T+ WRPP   G A +  Y++E        W + ++ L ++   T T +    +
Sbjct: 26977 TVTAEKITLLWRPPADDGGAKITHYIVEKRETSRVVWSMVSEHL-EECIITTTKIIKGNE 27035

Query: 813   IFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQT-------YIRRVGEAVN 865
                RV+AVN  G  EP      +     + P    IP   K T       + R + +  +
Sbjct: 27036 YIFRVRAVNKYGIGEPLESDSVVAKNAFVTPGPPGIPEVTKITKNSMTVVWSRPIADGGS 27095

Query: 866   LVIPF--QGKPRPELTW---KKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQV 920
              +  +  + + +  L W    K+     + ++      +D    +     +  G +    
Sbjct: 27096 DISGYFLEKRDKKSLGWFKVLKETIRDTRQKVTGLTENSDYQYRVCAVNAAGQGPFS--- 27152

Query: 921   KVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADK 980
             +  +F + A      ID PGPP  ++I D    ++ L W+ P  DG +A+TGY ++    
Sbjct: 27153 EPSEFYKAADP----IDPPGPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVVEIRQG 27208

Query: 981   KSMEWFTVIE--HYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGK 1038
             +  EW TV        T   ++ L  G  YYFRV + N  G  E   M            
Sbjct: 27209 EEEEWTTVSTKGEVRTTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEM------------ 27256

Query: 1039  IYKNPVYEDFDFSEAPMFTQPLV---NTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIV 1095
                N   +  D  EAP     +    +  A AG +  +    +G P P +TW K++  + 
Sbjct: 27257 ---NEPVQAKDILEAPEIDLDVALRTSVIAKAGEDVQVLIPFKGRPPPTVTWRKDEKNLG 27313

Query: 1096  DDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLG 1133
              D RY + +      L I + +  D G Y     N +G
Sbjct: 27314 SDARYSIENTDSSSLLTIPQVTRNDTGKYILTIENGVG 27351



 Score = 98.6 bits (244), Expect = 3e-20
 Identities = 93/361 (25%), Positives = 149/361 (41%), Gaps = 12/361 (3%)

Query: 296   RFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEK 355
             +F  E++      +W K  QEI    ++     G +  + I +    D+++Y   A D+ 
Sbjct: 11858 KFECEVSREPKTFRWLKGTQEITGDDRFELIKDGTKHSMVIKSAAFEDEAKYMFEAEDKH 11917

Query: 356   CSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYR 415
              S +L +    +     L+D TA   E      E+S D+  VKWFKN + +         
Sbjct: 11918 TSGKLIIEGIRLKFLTPLKDVTAKEKESAVFTVELSHDNIRVKWFKNDQRL--HTTRSVS 11975

Query: 416   IRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEI 475
             ++ EGK H +  +  +  D ++  V   G  S AKL+V          L D T     E+
Sbjct: 11976 MQDEGKTHSITFKDLSIDDTSQIRVEAMGMSSEAKLTVLEGDPYFTGKLQDYTGVEKDEV 12035

Query: 476   CLKCEISE-NIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYN 534
              L+CEIS+ + P KW K+G  ++ S    +   G+   L++  AL  D G Y    D   
Sbjct: 12036 ILQCEISKADAPVKWFKDGKEIKPSKNAVIKADGKKRMLILKKALKSDIGQYTC--DCGT 12093

Query: 535   VTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWS-RGDKAIME 593
                  K+ + D    ++  L   ++V V+     R E  IS E    A W  +G+  +  
Sbjct: 12094 DKTSGKLDIEDREIKLVRPL---HSVEVMETETARFETEIS-EDDIHANWKLKGEALLQT 12149

Query: 594   GSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTV 653
                 I+ E    S  LV+     D +G       N    AH  +K +V+    P    TV
Sbjct: 12150 PDCEIKEEGKIHS--LVLHNCRLDQTGGVDFQAANVKSSAHLRVKPRVIGLLRPLKDVTV 12207

Query: 654   T 654
             T
Sbjct: 12208 T 12208



 Score = 95.9 bits (237), Expect = 2e-19
 Identities = 141/627 (22%), Positives = 240/627 (38%), Gaps = 54/627 (8%)

Query: 54   LERKDS-DWTLVETP-PGEEQAKQNANSQLSILFIEKPQGGTVKVGEDITFIAKVKAEDL 111
            LE  DS D+T + T   G ++       +    F++KP    V  G ++TF + VK    
Sbjct: 7744 LEESDSGDYTCIATNMAGSDECSAPLTVREPPSFVQKPDPMDVLTGTNVTFTSIVKGTPP 7803

Query: 112  LRKPTIKWFKGKWMDLASKAGKHLQLKETFERHSRVYTFEMQIIKAKDNFAGNYRCEVTY 171
                ++ WFKG   +L      ++ L+++          E+++     + +G Y C V+ 
Sbjct: 7804 F---SVSWFKGS-SELVPGDRCNVSLEDSVA--------ELELFDVDTSQSGEYTCIVSN 7851

Query: 172  KDKFDSCSFDLEVHESTGTTPNIDIRSAFKRSGEGQEDA--GELDFSGLLKRREVKQQEE 229
            +    SC+  L +         ++  S  K      E    G    S   K+  +     
Sbjct: 7852 EAGKASCTTHLYIKAPAKFVKRLNDYSIEKGKPLILEGTFTGTPPISVTWKKNGINVTPS 7911

Query: 230  EPQVDVWELLKNAK---PSEYEKIAFQYGITDLRGMLKRLKRMRREEKKSAAFAKILDPA 286
            + + ++    K+A    PS   + A QY         K     +    +   F K L+P 
Sbjct: 7912 Q-RCNITTTEKSAILEIPSSTVEDAGQYNCYIENASGKDSCSAQILILEPPYFVKQLEPV 7970

Query: 287  YQVDKGGRVRFVVELAD-PKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDS 345
             +V  G       +LA  P++ V WYK   ++RP+T Y    +     L  N   + D  
Sbjct: 7971 -KVSVGDSASLQCQLAGTPEIGVSWYKGDTKLRPTTTYKMHFRNNVATLVFNQVDINDSG 8029

Query: 346  EYYVTA----GDEKCSTELFVREP--PIMVTKQLEDTTAYCGERVELECEVS-EDDANVK 398
            EY   A    G+   ST L V+E   P   ++QL D     G  V  +C +S  +  +V 
Sbjct: 8030 EYICKAENSVGEVSASTFLTVQEQKLPPSFSRQLRDVQETVGLPVVFDCAISGSEPISVS 8089

Query: 399  WFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPL 458
            W+K+G+ +   P    +         L I    ++ A +YS   T    SA  S  L   
Sbjct: 8090 WYKDGKPLKDSP--NVQTSFLDNTATLNIFKTDRSLAGQYSCTATNPIGSASSSARLILT 8147

Query: 459  KILTP------LTDQTVNLGKEICLKCEISENIPGK--WTKNGLPVQESDRLKVVHKGRI 510
            +   P      L      +G+    +C ++   P K  W K+   ++   + ++ +    
Sbjct: 8148 EGKNPPFFDIRLAPVDAVVGESADFECHVTGTQPIKVSWAKDSREIRSGGKYQISYLENS 8207

Query: 511  HKLVIANALTEDEGDYV------FAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIA 564
              L +      D G Y          D+    L  K  +I PP           TV    
Sbjct: 8208 AHLTVLKVDKGDSGQYTCYAVNEVGKDSCTAQLNIKERLI-PPSFT---KRLSETVEETE 8263

Query: 565  GNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDI--AERDDSGVY 622
            GN  +LE  ++G  P    W + +  I   S     E    ++TLV+ +  A  +D+G+Y
Sbjct: 8264 GNSFKLEGRVAGSQPITVAWYKNNIEIQPTS---NCEITFKNNTLVLQVRKAGMNDAGLY 8320

Query: 623  HINLKNEAGEAHASIKVKVVDFPDPPV 649
               + N+AG A  +  + + +   PPV
Sbjct: 8321 TCKVSNDAGSALCTSSIVIKEPKKPPV 8347



 Score = 95.5 bits (236), Expect = 3e-19
 Identities = 111/492 (22%), Positives = 196/492 (39%), Gaps = 52/492 (10%)

Query: 673   GSPILGYFIERKKKQSSRWMRLNFDLCKET-TFEPKKMIEGVAYEVRIFAVNAIGISKPS 731
             G P+    + R        MR N ++  E  T   K+ +   A    I A N+ G +K  
Sbjct: 26502 GKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADAGRYEITAANSSGTTKAF 26561

Query: 732   MPSRPFVPLAVTSPPT-LLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWI 790
             +     V L    PPT  + +  +T+ +VT++W PP + G + +  Y+L      T  W 
Sbjct: 26562 IN---IVVLDRPGPPTGPVVISDITEESVTLKWEPPKYDGGSQVTNYILLKRETSTAVWT 26618

Query: 791   VANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVK---EIIEPPKIR 847
               +   + +T   +  L T  +   R+KA N  G S+    S  + VK       PP   
Sbjct: 26619 EVSAT-VARTMMKVMKLTTGEEYQFRIKAENRFGISD-HIDSACVTVKLPYTTPGPPSTP 26676

Query: 848   IPRHLKQTYI-----RRVGEAVNLVIPF--QGKPRPELTWKKDGAEIDKNQINIRNSETD 900
                ++ +  I       V    + V+ +  + K R  + W+K       N++ IR +   
Sbjct: 26677 WVTNVTRESITVGWHEPVSNGGSAVVGYHLEMKDRNSILWQK------ANKLVIRTTH-- 26728

Query: 901   TIIFIRKAERSHSGKYDLQVKVDKFVETA-----SIDIQIIDRPGPPQIVKIEDVWGENV 955
                  +    S    Y+ +V  +           S  +  ID   PP+ V+I D+   +V
Sbjct: 26729 ----FKVTTISAGLIYEFRVYAENAAGVGKPSHPSEPVLAIDACEPPRNVRITDISKNSV 26784

Query: 956   ALTWTPPKDDGNAAITGYTIQKADKKSMEWFTV-IEHYHRTSATITELVIGNEYYFRVFS 1014
             +L+W  P  DG + ITGY +++ D     W      +   T   I+ L   ++Y FRVF+
Sbjct: 26785 SLSWQQPAFDGGSKITGYIVERRDLPDGRWTKASFTNVTETQFIISGLTQNSQYEFRVFA 26844

Query: 1015  ENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAI---AGYNA 1071
              N  G     +++  S V+         P+    D    P+   PL  T  +   AG + 
Sbjct: 26845 RNAVG-----SISNPSEVVG--------PI-TCIDSYGGPVIDLPLEYTEVVKYRAGTSV 26890

Query: 1072  TLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVND 1131
              L   + G P P I W K+   +  +    + +   + ++ I+     + G Y  K  N 
Sbjct: 26891 KLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLASILIKDADRLNSGCYELKLRNA 26950

Query: 1132  LGTVEIECKLEV 1143
             +G+     ++++
Sbjct: 26951 MGSASATIRVQI 26962



 Score = 94.4 bits (233), Expect = 6e-19
 Identities = 105/462 (22%), Positives = 179/462 (38%), Gaps = 52/462 (11%)

Query: 697   DLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTD 756
             D C+E        +   A E  I  +N I + KP  P+ P            + +D VT 
Sbjct: 22209 DACREDVGHYVVKLTNSAGEA-IETLNVIVLDKPGPPTGP------------VKMDEVTA 22255

Query: 757   TTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVR 816
              ++T+ W PP + G + ++ Y++E     T  W + +   + +T      L T  +   R
Sbjct: 22256 DSITLSWGPPKYDGGSSINNYIVEKRDTSTTTWQIVSAT-VARTTIKACRLKTGCEYQFR 22314

Query: 817   VKAVNAAGAS-----EPKYYSQPILVKEIIEPPKIRIPRH--LKQTYIRRVGEAVNLVIP 869
             + A N  G S     EP     P  V      P + +     ++  +   + +  + VI 
Sbjct: 22315 IAAENRYGKSTYLNSEPTVAQYPFKVPGPPGTPVVTLSSRDSMEVQWNEPISDGGSRVIG 22374

Query: 870   F--QGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVE 927
             +  + K R  + W K    ++K  I     +T  +    + E   S +  + +     V 
Sbjct: 22375 YHLERKERNSILWVK----LNKTPIPQTKFKTTGLEEGVEYEFRVSAENIVGIGKPSKVS 22430

Query: 928   TASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFT 987
                +     D PG P+ + +      +V L W  P  DG + ITGY ++K +     W  
Sbjct: 22431 ECYVARDPCDPPGRPEAIIVTR---NSVTLQWKKPTYDGGSKITGYIVEKKELPEGRWMK 22487

Query: 988   V-IEHYHRTSATITELVIGNEYYFRVFSENMCGL-SEDATMTKESAVIARDG----KIYK 1041
                 +   T   +T LV  + Y FRV + N  G+ SE +  T   A+ ARD     +I  
Sbjct: 22488 ASFTNIIDTHFEVTGLVEDHRYEFRVIARNAAGVFSEPSEST--GAITARDEVDPPRISM 22545

Query: 1042  NPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYR 1101
             +P Y+D                   AG +  ++  + G P P I W+K    + +  R  
Sbjct: 22546 DPKYKD--------------TIVVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTARLE 22591

Query: 1102  MFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1143
             + S     +L ++     D G Y  KA N  G   +   ++V
Sbjct: 22592 IKSTDFATSLSVKDAVRVDSGNYILKAKNVAGERSVTVNVKV 22633



 Score = 94.4 bits (233), Expect = 6e-19
 Identities = 148/652 (22%), Positives = 260/652 (39%), Gaps = 111/652 (17%)

Query: 51    SRALERKDSDWTLVE---TPPGEEQAKQNANSQLSILFIEKPQGGTVKVGEDITFIAKVK 107
             S+  E K SD    E   T   E +A +  +S+  I  +   Q  TV       F  K  
Sbjct: 32819 SKISETKKSDQKTTESTVTRKTEPKAPEPISSKPVI--VTGLQDTTVSSDSVAKFAVKAT 32876

Query: 108   AEDLLRKPTIKWFK--------GKWMDLASKAGKHLQLKETFERHSRVYTFEMQIIKAKD 159
              E    +PT  W K        GK+     K G  L++ +T    S +YT  ++      
Sbjct: 32877 GEP---RPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVK------ 32927

Query: 160   NFAGNYR--CEVTYKDKFDSCSFDLEVHESTGTTPNIDIRSAFKRSGEGQEDAGELDFSG 217
             N AG+    C++T K   D+ +  +   +++  TP        K++   +E + +   S 
Sbjct: 32928 NSAGSVSSSCKLTIKAIKDTEAQKVSTQKTSEITPQ-------KKAVVQEEISQKALRSE 32980

Query: 218   LLKRREVKQQE------EEPQVDVWELLKNAKPSEYEKIAFQYGITDLRGMLKRLKRMRR 271
              +K  E K QE      E  +V + E +K +  +  EK      IT              
Sbjct: 32981 EIKMSEAKSQEKLALKEEASKVLISEEVKKSAATSLEKSIVHEEITKTS--------QAS 33032

Query: 272   EEKKSAAFAKILDPAYQVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQ 331
             EE ++ A  K       +++G R+     +A    +VKW  NG E+  S +Y +   G  
Sbjct: 33033 EEVRTHAEIKAFSTQMSINEGQRLVLKANIAGAT-DVKWVLNGVELTNSEEYRYGVSGSD 33091

Query: 332   RILFINNCQMTDDSEYYVTA----GDEKCSTELFVREPPIMVTKQLEDTTAYC------- 380
             + L I      D+      +    G  KC  +L        ++K+L D  A+        
Sbjct: 33092 QTLTIKQASHRDEGILTCISKTKEGIVKCQYDL-------TLSKELSDAPAFISQPRSQN 33144

Query: 381   ---GERVELECEVS-EDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAA 436
                G+ V   CE+S E    ++WFKN   I     S   I      + L I  A+ +D+ 
Sbjct: 33145 INEGQNVLFTCEISGEPSPEIEWFKNNLPI--SISSNVSISRSRNVYSLEIRNASVSDSG 33202

Query: 437   EYSVMTTG--GQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCEISENIPGKWTKNGL 494
             +Y++      GQ SA  S+      ++ PL ++     +E+ L+     ++ G ++   +
Sbjct: 33203 KYTIKAKNFRGQCSATASL------MVLPLVEEP---SREVVLRTSGDTSLQGSFSSQSV 33253

Query: 495   PVQESDR-----------LKVVHKGRIHKLVIANALTEDEGDYVFAPDAY----NVT--- 536
              +  S +              + + +   +   +  +  E     +  ++    N+T   
Sbjct: 33254 QMSASKQEASFSSFSSSSASSMTEMKFASMSAQSMSSMQESFVEMSSSSFMGISNMTQLE 33313

Query: 537   ------LPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKA 590
                   L A +  I PPKI  + L +D  +++  G  L +    +GEP P+  WS G + 
Sbjct: 33314 SSTSKMLKAGIRGI-PPKI--EALPSD--ISIDEGKVLTVACAFTGEPTPEVTWSCGGRK 33368

Query: 591   I-MEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKV 641
             I  +  GR   E+  D +TL+I   ++ D G+Y ++L NE G   A++ + +
Sbjct: 33369 IHSQEQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHI 33420



 Score = 93.2 bits (230), Expect = 1e-18
 Identities = 201/953 (21%), Positives = 329/953 (34%), Gaps = 190/953 (19%)

Query: 284   DPAYQVDKGGRVRFVVEL-ADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMT 342
             D  Y   +    R  + +   P   V W K    +   T+   E       L + +CQ +
Sbjct: 19989 DLCYLAKENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKS 20048

Query: 343   DDSEYYVT----AGDEKCSTELFVREPPIMVTKQL--EDTTAYC------------GERV 384
             D  +Y +T    AG ++ +  + V   P + T  +  ++ TA              G  +
Sbjct: 20049 DAGKYTITLKNVAGTKEGTISIKVVGKPGIPTGPIKFDEVTAEAMTLKWAPPKDDGGSEI 20108

Query: 385   ELECEVSEDDANVKWFKNGEEIIPGPKSRYRI-----------RVEGKKHILIIEGATKA 433
                     D  N KW      +    K+ +R+           RV  +    + EG    
Sbjct: 20109 TNYILEKRDSVNNKWVTCASAV---QKTTFRVTRLHEGMEYTFRVSAENKYGVGEGLKSE 20165

Query: 434   DAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEIC-LKCEISENIPGKWTK- 491
                                VD++   +    TD     G  I     E  E     W + 
Sbjct: 20166 PIVARHPFDVPDAPPPPNIVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRA 20225

Query: 492   NGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKIIL 551
             N  P++  D  KV              LTE   +Y F   A N+    K  +   P + L
Sbjct: 20226 NKTPIRMRD-FKVT------------GLTEGL-EYEFRVMAINLAGVGKPSLPSEPVVAL 20271

Query: 552   DGLDAD----------NTVTVI-------AGNKLRLEIPISGEPPPKAMWSRGDKAIMEG 594
             D +D            N+VT+I        G+KL   I    + P K+ W + +      
Sbjct: 20272 DPIDPPGKPEVINITRNSVTLIWTEPKYDGGHKLTGYIVEKRDLPSKS-WMKANHV---- 20326

Query: 595   SGRIRTESYPDSSTLVIDIAERDDSGVYH--INLKNEAGEAHA-SIKVKVVDFPDPPVAP 651
                    + P+ +  V D+ E    G Y   I  KN AG   A S   + +   D   AP
Sbjct: 20327 -------NVPECAFTVTDLVE---GGKYEFRIRAKNTAGAISAPSESTETIICKDEYEAP 20376

Query: 652   TVTEVGDDWCIMNWEPPAYDG-----GSPIL--GYFIERKKKQSSRWMRLNFDL----CK 700
             T+            +P   DG     G  I+     I  K    S W +   D+      
Sbjct: 20377 TIV----------LDPTIKDGLTIKAGDTIVLNAISILGKPLPKSSWSKAGKDIRPSDIT 20426

Query: 701   ETTFEPKKMIEGVAYEVR-------IFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDS 753
             + T  P   +  + Y  R       I A N  G     +       L V  PP  + + +
Sbjct: 20427 QITSTPTSSMLTIKYATRKDAGEYTITATNPFGTKVEHVK---VTVLDVPGPPGPVEISN 20483

Query: 754   VTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKI 813
             V+    T+ W PP   G + +  Y+LE        W V ++D I   +   T L    + 
Sbjct: 20484 VSAEKATLTWTPPLEDGGSPIKSYILEKRETSRLLWTVVSED-IQSCRHVATKLIQGNEY 20542

Query: 814   FVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGK 873
               RV AVN  G  EP   S+P+ + +   PP                G      +    K
Sbjct: 20543 IFRVSAVNHYGKGEP-VQSEPVKMVDRFGPP----------------GPPEKPEVSNVTK 20585

Query: 874   PRPELTWKKD----GAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETA 929
                 ++WK+     G+EI    +  R  E  ++ ++R  +   S   DL+ KV    E +
Sbjct: 20586 NTATVSWKRPVDDGGSEITGYHVERR--EKKSLRWVRAIKTPVS---DLRCKVTGLQEGS 20640

Query: 930   SIDIQIIDR-----------------------PGPPQIVKIEDVWGENVALTWTPPKDDG 966
             + + ++                          PGPP    + D   ++ +L W  P  DG
Sbjct: 20641 TYEFRVSAENRAGIGPPSEASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLAWGKPHYDG 20700

Query: 967   NAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGN-----EYYFRVFSENMCGLS 1021
                ITGY ++        W   I+    T+  IT+ V+ +     +Y FR+ + N  G+ 
Sbjct: 20701 GLEITGYVVEHQKVGDEAW---IKDTTGTALRITQFVVPDLQTKEKYNFRISAINDAGVG 20757

Query: 1022  EDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAI-AGYNATLNCSVRGN 1080
             E A +         D +I +  +  DF+          L  T  + AG +  +   ++G 
Sbjct: 20758 EPAVIP--------DVEIVEREMAPDFELDAE------LRRTLVVRAGLSIRIFVPIKGR 20803

Query: 1081  PKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLG 1133
             P P++TW K+ + + +  R  + + +    L I + + YD G +     N  G
Sbjct: 20804 PAPEVTWTKDNINLKN--RANIENTESFTLLIIPECNRYDTGKFVMTIENPAG 20854



 Score = 93.2 bits (230), Expect = 1e-18
 Identities = 127/584 (21%), Positives = 221/584 (37%), Gaps = 94/584 (16%)

Query: 606   SSTLVIDIAERDDSGV--YHINLKNEAGEAH----ASIKVKV------VDFPDPPVAPTV 653
             S T  I++++  +  V  + +  KNE G +       I VK       VD  D P A   
Sbjct: 27515 SKTCEIEVSQLKEQSVLEFRVFAKNEKGLSDPVTIGPITVKELIITPEVDLSDIPGAQVT 27574

Query: 654   TEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKET-TFEPKKMIEG 712
               +G +   ++ E P      P + +  +    + S ++R +    K T + +  K   G
Sbjct: 27575 VRIGHN---VHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHG 27631

Query: 713   VAYEVRI--------FAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWR 764
               Y V +          +  I +  PS P  P            +  D +   +V + W 
Sbjct: 27632 GKYTVILDNAVCRIAVPITVITLGPPSKPKGP------------IRFDEIKADSVILSWD 27679

Query: 765   PPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAG 824
              P+  G   +  Y +E       +W +     + +T F +  L  DA+   RV+A N  G
Sbjct: 27680 VPEDNGGGEITCYSIEKRETSQTNWKMVCSS-VARTTFKVPNLVKDAEYQFRVRAENRYG 27738

Query: 825   ASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKD- 883
              S      QP++   I+   + RIP           G+ V   +   G     LTW    
Sbjct: 27739 VS------QPLVSSIIVAKHQFRIPGP--------PGKPVIYNVTSDGM---SLTWDAPV 27781

Query: 884   ---GAEIDKNQINIRNSETDTIIFIRKAERSHSGK------------YDLQVKVDKFVET 928
                G+E+     ++   E ++I++ +      SG+            Y  +V  +     
Sbjct: 27782 YDGGSEV--TGFHVEKKERNSILWQKVNTSPISGREYRATGLVEGLDYQFRVYAENSAGL 27839

Query: 929   AS--------IDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADK 980
             +S        + +  +D PG P  +   DV  E + L W PP  DG + I GY+I+K   
Sbjct: 27840 SSPSDPSKFTLAVSPVDPPGTPDYI---DVTRETITLKWNPPLRDGGSKIVGYSIEKRQG 27896

Query: 981   KSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIY 1040
                              T+T L  G+ Y FR+ + N  G     + +    ++ RD  + 
Sbjct: 27897 NERWVRCNFTDVSECQYTVTGLSPGDRYEFRIIARNAVGTISPPSQSS-GIIMTRDENV- 27954

Query: 1041  KNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRY 1100
               P   +F     P +   L+     +G +  +   V+G P P++TW K+ V I      
Sbjct: 27955 --PPIVEF----GPEYFDGLIIK---SGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNM 28005

Query: 1101  RMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVK 1144
              +    G  +L +R  +    G Y  +A N  G+ + E K++V+
Sbjct: 28006 EITDVLGSTSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQ 28049



 Score = 92.8 bits (229), Expect = 2e-18
 Identities = 113/454 (24%), Positives = 172/454 (37%), Gaps = 74/454 (16%)

Query: 718   RIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGY 777
             R  AVN   + KP  P+ P            L ++ +T    ++ W  P   G A +D Y
Sbjct: 25871 RSVAVNCKVLDKPGPPAGP------------LEINGLTAEKCSLSWGRPQEDGGADIDYY 25918

Query: 778   VLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILV 837
             ++E        W +   +L   T   +T L    +   RV  VN  G  EP    + + +
Sbjct: 25919 IVEKRETSHLAWTICEGEL-QMTSCKVTKLLKGNEYIFRVTGVNKYGVGEPL---ESVAI 25974

Query: 838   KEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNS 897
             K +        P  L+ T + +  E++ L        RPE      G+EI    I  R  
Sbjct: 25975 KALDPFTVPSPPTSLEITSVTK--ESMTLCWS-----RPE---SDGGSEISGYIIERR-- 26022

Query: 898   ETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQI---------------------- 935
             E +++ ++R  ++     YDL+VK     E    + ++                      
Sbjct: 26023 EKNSLRWVRVNKKP---VYDLRVKSTGLREGCEYEYRVYAENAAGLSLPSETSPLIRAED 26079

Query: 936   -IDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHR 994
              +  P PP   KI D     + + W  P  DG A ITGYT++       +W T I+    
Sbjct: 26080 PVFLPSPPSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEYKKSDDTDWKTSIQSLRG 26139

Query: 995   TSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAP 1054
             T  TI+ L  G EY FRV S N  G S+ +  +        D +I K    E     ++ 
Sbjct: 26140 TEYTISGLTTGAEYVFRVKSVNKVGASDPSDSS--------DPQIAKEREEEPLFDIDSE 26191

Query: 1055  MFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMF--SNQGVCTLE 1112
             M    +V     AG + T+    RG P P + W K       D R R +  +     +L 
Sbjct: 26192 MRKTLIVK----AGASFTMTVPFRGRPVPNVLWSKPDT----DLRTRAYVDTTDSRTSLT 26243

Query: 1113  IRKPSPYDGGTYCCKAVNDLGTVEIECKLEVKVI 1146
             I   +  D G Y     N L    +   L VKV+
Sbjct: 26244 IENANRNDSGKYTLTIQNVLSAASL--TLVVKVL 26275



 Score = 92.4 bits (228), Expect = 2e-18
 Identities = 133/609 (21%), Positives = 230/609 (37%), Gaps = 111/609 (18%)

Query: 584   WSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVD 643
             WSR +K+++    +   +   +  T V  +   + +G    +  ++   AH  I      
Sbjct: 14948 WSRVNKSLLNAL-KANVDGLLEGLTYVFRVCAENAAGPGKFSPPSDPKTAHDPISP---- 15002

Query: 644   FPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETT 703
              P PP+ P VT+       + WEPPA++GG  I+GYF++++   ++ W R    + K   
Sbjct: 15003 -PGPPI-PRVTDTSSTTIELEWEPPAFNGGGEIVGYFVDKQLVGTNEWSRCTEKMIKVRQ 15060

Query: 704   FEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRW 763
             +  K++ EG  Y++R+ AVNA G   P        P+ V  P                  
Sbjct: 15061 YTVKEIREGADYKLRVSAVNAAGEGPPGETQ----PVTVAEPQ----------------- 15099

Query: 764   RPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAA 823
              PP    A  LD  V      G +  I+A K L  +    +TG P   K++ +       
Sbjct: 15100 EPP----AVELDVSVKG----GIQ--IMAGKTL--RIPAVVTGRPVPTKVWTK------- 15140

Query: 824   GASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLV--------IPFQGKPR 875
                E +     +++  +    ++ I   L++ + R V  A N          +     P 
Sbjct: 15141 --EEGELDKDRVVIDNVGTKSELIIKDALRKDHGRYVITATNSCGSKFAAARVEVFDVPG 15198

Query: 876   PELTWKKDGAEIDKNQINIRNSETDT------IIFIRKAERSHSGKYDLQVKVDKFVETA 929
             P L  K          +N  + E D        I  RK  + H+ +  ++ +  K   T 
Sbjct: 15199 PVLDLKPVVTNRKMCLLNWSDPEDDGGSEITGFIIERKDAKMHTWRQPIETERSKCDITG 15258

Query: 930   SID------------------------IQIIDRPGPP---QIVKIEDVWGENVALTWTPP 962
              ++                        I  +D  GPP   + +   +     + L W  P
Sbjct: 15259 LLEGQEYKFRVIAKNKFGCGPPVEIGPILAVDPLGPPTSPERLTYTERTKSTITLDWKEP 15318

Query: 963   KDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYY-FRVFSENMCGLS 1021
             + +G + I GY I+K      ++  V +    T++ + E +  ++ Y FRV + N  G S
Sbjct: 15319 RSNGGSPIQGYIIEKRRHDKPDFERVNKRLCPTTSFLVENLDEHQMYEFRVKAVNEIGES 15378

Query: 1022  EDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAI-AGYNATLNCSVRGN 1080
             E +       V+ +D ++               +      +T  + AG    +   V G 
Sbjct: 15379 EPSLPLN---VVIQDDEVPPT----------IKLRLSVRGDTIKVKAGEPVHIPADVTGL 15425

Query: 1081  PKPKITWMKNKVAI------VDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGT 1134
             P PKI W KN+  I      +   +  +  ++    L I K    D GTY   A N LG+
Sbjct: 15426 PMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAVREDKGTYTVTASNRLGS 15485

Query: 1135  VEIECKLEV 1143
             V     +EV
Sbjct: 15486 VFRNVHVEV 15494



 Score = 92.0 bits (227), Expect = 3e-18
 Identities = 98/417 (23%), Positives = 169/417 (40%), Gaps = 47/417 (11%)

Query: 745   PPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTI 804
             PP  + +D V+  ++T+ W PP++ G   +  Y++E     +  W + ++  + +T   I
Sbjct: 25490 PPGPIRIDEVSCDSITISWNPPEYDGGCQISNYIVEKKETTSTTWHIVSQ-AVARTSIKI 25548

Query: 805   TGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPP----KIRIPRHLKQTYIRR- 859
               L T ++   RV A N  G S     S  ++ +    PP      ++    K T +   
Sbjct: 25549 VRLTTGSEYQFRVCAENRYGKSSYSE-SSAVVAEYPFSPPGPPGTPKVVHATKSTMLVTW 25607

Query: 860   ---VGEAVNLVIPF--QGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSG 914
                V +  + VI +  + K R  + W K       N+I I     DT + +   +     
Sbjct: 25608 QVPVNDGGSRVIGYHLEYKERSSILWSK------ANKILI----ADTQMKVSGLDEGLMY 25657

Query: 915   KYDLQVKVDKFVETASIDIQII------DRPGPPQIVKIEDVWGENVALTWTPPKDDGNA 968
             +Y +  +    +   S   + +      D PG P++  I     ++V+L W+ P  DG A
Sbjct: 25658 EYRVYAENIAGIGKCSKSCEPVPARDPCDPPGQPEVTNITR---KSVSLKWSKPHYDGGA 25714

Query: 969   AITGYTIQKADKKSMEWFTV-IEHYHRTSATITELVIGNEYYFRVFSENMC-GLSEDATM 1026
              ITGY +++ +     W      +   T   +TEL     Y FRVF+ N    +SE +  
Sbjct: 25715 KITGYIVERRELPDGRWLKCNYTNIQETYFEVTELTEDQRYEFRVFARNAADSVSEPSES 25774

Query: 1027  TKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKIT 1086
             T    +I +D  +    V  D  F +  +           AG    +N  + G P P I+
Sbjct: 25775 T--GPIIVKDD-VEPPRVMMDVKFRDVIVVK---------AGEVLKINADIAGRPLPVIS 25822

Query: 1087  WMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGT--VEIECKL 1141
             W K+ + I +  R  + S      L ++     D G Y     N  GT  V + CK+
Sbjct: 25823 WAKDGIEIEERARTEIISTDNHTLLTVKDCIRRDTGQYVLTLKNVAGTRSVAVNCKV 25879



 Score = 92.0 bits (227), Expect = 3e-18
 Identities = 69/216 (31%), Positives = 100/216 (46%), Gaps = 18/216 (8%)

Query: 937   DRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTV-IEHYHRT 995
             ++PG P    I  V  ++  + W PP  DG A I  Y ++K +KK  +W +V  E    T
Sbjct: 30823 EKPGAPGKPTITAVTKDSCVVAWKPPASDGGAKIRNYYLEKREKKQNKWISVTTEEIRET 30882

Query: 996   SATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFS-EAP 1054
               ++  L+ G EY FRV  EN+ G SE + +++              P+    D   +AP
Sbjct: 30883 VFSVKNLIEGLEYEFRVKCENLGGESEWSEISE--------------PITPKSDVPIQAP 30928

Query: 1055  MFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMK-NKVAIVDDPRYRMFS-NQGVCTLE 1112
              F + L N       NATL C V G+PKP + W +  K  I D  +YR+     G   L 
Sbjct: 30929 HFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQLI 30988

Query: 1113  IRKPSPYDGGTYCCKAVNDLGTVEIECKLEVKVIAQ 1148
             I   +  D   Y  +A N  G+V     LEV+V A+
Sbjct: 30989 IASVTDDDATVYQVRATNQGGSVSGTASLEVEVPAK 31024



 Score = 90.9 bits (224), Expect = 6e-18
 Identities = 99/442 (22%), Positives = 167/442 (37%), Gaps = 60/442 (13%)

Query: 722   VNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEY 781
             +  + +  P  P  PF             +  +     ++ W  P   G + +  Y++E 
Sbjct: 18984 IKVVVMDAPGPPQPPF------------DISDIDADACSLSWHIPLEDGGSNITNYIVEK 19031

Query: 782   CFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEI- 840
             C     DW+ A    + KT   +  L    +   RV+A N  G SEP   + P +V +  
Sbjct: 19032 CDVSRGDWVTALAS-VTKTSCRVGKLIPGQEYIFRVRAENRFGISEP--LTSPKMVAQFP 19088

Query: 841   ----IEPPKIRIPRHLKQ----TYIRRVGEAVNLVIPF--QGKPRPELTWKKDGAEIDKN 890
                  EP   R+ +  K      + R   +  + +I +  + K R  L W K       N
Sbjct: 19089 FGVPSEPKNARVTKVNKDCIFVAWDRPDSDGGSPIIGYLIERKERNSLLWVK------AN 19142

Query: 891   QINIRNSETDTIIFIRKAERS------HSGKYDLQVKVDKFVETASIDIQIIDRPGPPQI 944
                +R++E      +   E S      +        K  ++V TA + +   D PG P++
Sbjct: 19143 DTLVRSTEYPCAGLVEGLEYSFRIYALNKAGSSPPSKPTEYV-TARMPV---DPPGKPEV 19198

Query: 945   VKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWF---TVIEHYHRTSATITE 1001
             +   DV    V+L W  PK DG + I GY ++       +W    T      +   T T 
Sbjct: 19199 I---DVTKSTVSLIWARPKHDGGSKIIGYFVEACKLPGDKWVRCNTAPHQIPQEEYTATG 19255

Query: 1002  LVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLV 1061
             L    +Y FR  +     +S  +  +    ++A +      P   D   +   + T    
Sbjct: 19256 LEEKAQYQFRAIARTAVNISPPSEPSDPVTILAENV-----PPRIDLSVAMKSLLTVK-- 19308

Query: 1062  NTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDG 1121
                  AG N  L+ +V G P P ++W K+   +      +M   + +CTLE+   +  D 
Sbjct: 19309 -----AGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDS 19363

Query: 1122  GTYCCKAVNDLGTVEIECKLEV 1143
             G Y   A N  G+     KL+V
Sbjct: 19364 GDYTITAENSSGSKSATIKLKV 19385



 Score = 89.4 bits (220), Expect = 2e-17
 Identities = 117/543 (21%), Positives = 204/543 (37%), Gaps = 60/543 (11%)

Query: 628   NEAGEAHASIKVKVVDFPDP-----PVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIE 682
             N AG   AS+        DP     P  P VT+       + W PP  DGGS + GY +E
Sbjct: 16399 NAAGVGPASLPSDPATARDPIAPPGPPFPKVTDWTKSSADLEWSPPLKDGGSKVTGYIVE 16458

Query: 683   RKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAV 742
              K++    W +      + T      + EG  Y+   F V A+ I+    P    V   +
Sbjct: 16459 YKEEGKEEWEKGKDKEVRGTKLVVTGLKEGAFYK---FRVRAVNIAGIGEPGE--VTDVI 16513

Query: 743   TSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKF 802
                  L++ D   D +V  R R   H G        +      T  W +  + L  +   
Sbjct: 16514 EMKDRLVSPDLQLDASV--RDRIVVHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEATI 16571

Query: 803   TITGLPTDAKI---------FVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIP---- 849
               T + +   I            + A N AG  +     + I+V  +  P  +  P    
Sbjct: 16572 ETTAISSSMVIKNCQRSHQGVYSLLAKNEAGERK-----KTIIVDVLDVPGPVGTPFLAH 16626

Query: 850   ----RHLKQTYIRRVGEAVNLVIPF--QGKPRPELTWKKDGAEIDKNQINIRNSETDTII 903
                    K T+     +  + +  +  + +      W      + +    ++        
Sbjct: 16627 NLTNESCKLTWFSPEDDGGSPITNYVIEKRESDRRAWTPVTYTVTRQNATVQGLIQGKAY 16686

Query: 904   FIRKAERSHSGKYDLQVKVDKFVETASIDI--QIIDRPGPPQIVKIEDVWGENVALTWTP 961
             F R A  +  G       +  FVET+   +  + I  P  P+ +++++V    V LTW P
Sbjct: 16687 FFRIAAENSIG-------MGPFVETSEALVIREPITVPERPEDLEVKEVTKNTVTLTWNP 16739

Query: 962   PKDDGNAAITGYTIQKADKKSMEWFTVI-EHYHRTSATITELVIGNEYYFRVFSENMCGL 1020
             PK DG + I  Y ++     + ++  V  ++      T+  L  G+ Y +RV + N+ G 
Sbjct: 16740 PKYDGGSEIINYVLESRLIGTEKFHKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQ 16799

Query: 1021  SEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGN 1080
              + +  TK    I    ++    ++ DF        T  +   +A+ G  +       G 
Sbjct: 16800 GKPSFCTKP---ITCKDELAPPTLHLDF----RDKLTIRVGEAFALTGRYS-------GK 16845

Query: 1081  PKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECK 1140
             PKPK++W K++  +++D R  + +      LE  K    D G YC    N  G+ +  C+
Sbjct: 16846 PKPKVSWFKDEADVLEDDRTHIKTTPATLALEKIKAKRSDSGKYCVVVENSTGSRKGFCQ 16905

Query: 1141  LEV 1143
             + V
Sbjct: 16906 VNV 16908



 Score = 87.0 bits (214), Expect = 9e-17
 Identities = 96/437 (21%), Positives = 162/437 (37%), Gaps = 75/437 (17%)

Query: 625   NLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERK 684
             N+  ++  +  S  +  +D  DPP  P    +      + W  P Y GG  I  Y +E++
Sbjct: 21337 NMAGKSKPSKPSEPMLALDPIDPPGKPVPLNITRHTVTLKWAKPEYTGGFKITSYIVEKR 21396

Query: 685   KKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIG-ISKPSMPSRPFVPLAVT 743
                + RW++ NF    E  F    + E  AYE R+ A NA G IS PS PS         
Sbjct: 21397 DLPNGRWLKANFSNILENEFTVSGLTEDAAYEFRVIAKNAAGAISPPSEPSDAITCRDDV 21456

Query: 744   SPPTLLTVDSVTDTTV-------------------TMRWRP--PDHIGAAGLDGYVLEYC 782
               P +       DT +                   TM W     +  G A L+  + ++ 
Sbjct: 21457 EAPKIKVDVKFKDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFS 21516

Query: 783   FEGTEDWIVANKDLI--DKTKFTITGLPTD--AKIFVRVKAVNAAGASEPKYYSQPILVK 838
                     + NKD    D   +T+T       AK    VK ++  G  E      P+ V 
Sbjct: 21517 TN------LVNKDSTRRDSGAYTLTATNPGGFAKHIFNVKVLDRPGPPE-----GPLAVT 21565

Query: 839   EIIE--------PPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKN 890
             E+          PP            +   G  ++  I  Q +    L W    +E+   
Sbjct: 21566 EVTSEKCVLSWFPP------------LDDGGAKIDHYI-VQKRETSRLAWTNVASEVQVT 21612

Query: 891   QINI-RNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIED 949
             ++ + +  + +  IF   A   +     L+           + +     P PP+  ++  
Sbjct: 21613 KLKVTKLLKGNEYIFRVMAVNKYGVGEPLE-------SEPVLAVNPYGPPDPPKNPEVTT 21665

Query: 950   VWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWF-----TVIEHYHRTSATITELVI 1004
             +  +++ + W  P  DG + I  Y +++ DK    W      T+ +  ++ S     L  
Sbjct: 21666 ITKDSMVVCWGHPDSDGGSEIINYIVERRDKAGQRWIKCNKKTLTDLRYKVSG----LTE 21721

Query: 1005  GNEYYFRVFSENMCGLS 1021
             G+EY FR+ +EN  G+S
Sbjct: 21722 GHEYEFRIMAENAAGIS 21738



 Score = 86.3 bits (212), Expect = 2e-16
 Identities = 94/359 (26%), Positives = 158/359 (44%), Gaps = 23/359 (6%)

Query: 310   WYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVT---AGDEKCST-ELFVREP 365
             W K+G  IR S K+ F   G  R L I + Q++D  EY         EK ST +L V E 
Sbjct: 11151 WMKDGSNIRESPKHRFIADGKDRKLHIIDVQLSDAGEYTCVLRLGNKEKTSTAKLVVEEL 11210

Query: 366   PIMVTKQL-EDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHI 424
             P+   K L E+ T   G+ + L CE+++ + +V W K+G+ ++  P  R    V G    
Sbjct: 11211 PVRFVKTLEEEVTVVKGQPLYLSCELNK-ERDVVWRKDGKIVVEKP-GRIVPGVIGLMRA 11268

Query: 425   LIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKIL-----TPLTDQTVNLGKEICLKC 479
             L I  A   DA  Y+V T    ++ + S  +K ++++      P+ DQ V         C
Sbjct: 11269 LTINDADDTDAGTYTV-TVENANNLECSSCVKVVEVIRDWLVKPIRDQHVKPKGTAIFAC 11327

Query: 480   EISENIPG-KWTK--NGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVT 536
             +I+++ P  KW K  + +P + +D+ +++  G    L I NA+ ED  +Y  A +     
Sbjct: 11328 DIAKDTPNIKWFKGYDEIPAEPNDKTEILRDGNHLYLKIKNAMPEDIAEY--AVEIEGKR 11385

Query: 537   LPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSG 596
              PAK+ + +    +L  ++    VT+        +  IS    P     +G+  ++  S 
Sbjct: 11386 YPAKLTLGEREVELLKPIE---DVTIYEKESASFDAEISEADIPGQWKLKGE--LLRPSP 11440

Query: 597   RIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTE 655
                 ++      L +   + D +G       N    A  ++K   +DF  P    TV E
Sbjct: 11441 TCEIKAEGGKRFLTLHKVKLDQAGEVLYQALNAITTAILTVKEIELDFAVPLKDVTVPE 11499



 Score = 86.3 bits (212), Expect = 2e-16
 Identities = 104/434 (23%), Positives = 164/434 (37%), Gaps = 44/434 (10%)

Query: 722   VNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEY 781
             ++ I + KP  P  P            +  D V+   V + W PP + G   +  Y++E 
Sbjct: 24397 LSVIVLEKPGPPVGP------------VRFDEVSADFVVISWEPPAYTGGCQISNYIVEK 24444

Query: 782   CFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILV---- 837
                 T  W + +   + +T   IT L T  +   R+ A N  G S P   S+ ++V    
Sbjct: 24445 RDTTTTTWHMVSAT-VARTTIKITKLKTGTEYQFRIFAENRYGKSAP-LDSKAVIVQYPF 24502

Query: 838   KEIIEPPKIRIPRHLKQTYIRRVGEAVN------LVIPFQGKPRPELTWKKDGAEIDKNQ 891
             KE   P    +    K   + +  E VN      +    + K +  + W K    ++K  
Sbjct: 24503 KEPGPPGTPFVTSISKDQMLVQWHEPVNDGGTKIIGYHLEQKEKNSILWVK----LNKTP 24558

Query: 892   INIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVW 951
             I     +T  +    + E   S +  + +     V    +     D PG P+ + I    
Sbjct: 24559 IQDTKFKTTGLDEGLEYEFKVSAENIVGIGKPSKVSECFVARDPCDPPGRPEAIVITR-- 24616

Query: 952   GENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTV-IEHYHRTSATITELVIGNEYYF 1010
               NV L W  P  DG + ITGY ++K D     W      +   T  T++ LV    Y F
Sbjct: 24617 -NNVTLKWKKPAYDGGSKITGYIVEKKDLPDGRWMKASFTNVLETEFTVSGLVEDQRYEF 24675

Query: 1011  RVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYN 1070
             RV + N  G   + +     A+ ARD     N   +       P +   +V     AG  
Sbjct: 24676 RVIARNAAGNFSEPS-DSSGAITARDEIDAPNASLD-------PKYKDVIV---VHAGET 24724

Query: 1071  ATLNCSVRGNPKPKITWMKNKVAIVDD-PRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAV 1129
               L   +RG P P + W K+   + +   R  + S     TL ++     DGG Y  K  
Sbjct: 24725 FVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQYILKLS 24784

Query: 1130  NDLGTVEIECKLEV 1143
             N  GT  I   ++V
Sbjct: 24785 NVGGTKSIPITVKV 24798



 Score = 86.3 bits (212), Expect = 2e-16
 Identities = 78/292 (26%), Positives = 125/292 (42%), Gaps = 60/292 (20%)

Query: 290   DKGGRVRFV--VELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEY 347
             ++GG V++V  +E  D   +V WY   +++  S KY   ++    IL++ +    DD  Y
Sbjct: 31580 EEGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTY 31639

Query: 348   YVTA----GDEKCSTELFVR---------------------------EPPIMVTKQLEDT 376
                     G++    ELFV+                           E P   T  L + 
Sbjct: 31640 RCKVVNDYGEDSSYAELFVKGVREVYDYYCRRTMKKIKRRTDTMRLLERPPEFTLPLYNK 31699

Query: 377   TAYCGERVELECEVS-EDDANVKWFKNGEEIIPGPK-SRYRIRVEGKKHILIIEGATKAD 434
             TAY GE V     ++   + +V W+K+G++I PG    +Y    +   + L I   T  D
Sbjct: 31700 TAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDD 31759

Query: 435   AAEYSVMTTG--GQSS--AKLSVDLKPLKILTPLTDQTV-------------NLGKEICL 477
              AEY+V+     G+ S  AKL+V L P     P TD T+               G+ +C 
Sbjct: 31760 DAEYTVVARNKYGEDSCKAKLTVTLHP-----PPTDSTLRPMFKRLLANAECQEGQSVCF 31814

Query: 478   KCEISENIPG--KWTKNGLPVQESDRLKVVHKG-RIHKLVIANALTEDEGDY 526
             +  +S   P   KW K+G P+     ++++H+G   + L I + L ED G Y
Sbjct: 31815 EIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYY 31866



 Score = 85.9 bits (211), Expect = 2e-16
 Identities = 91/401 (22%), Positives = 161/401 (40%), Gaps = 47/401 (11%)

Query: 288  QVDKGGRVRFVVELADPKLEVKWYKNGQEI----RPSTKYIFEHKGCQRILFINNCQMTD 343
            QV +  R     E+ +  ++  WYK+G EI    +   KY+ E +     +FI+  + +D
Sbjct: 3157 QVIEKQRAVVEFEVNEDDVDAHWYKDGIEINFQVQERHKYVVERR--IHRMFISETRQSD 3214

Query: 344  DSEYYVTAGDEKCSTELFVREP-PIMVTKQLEDTTAYCGERVELECEVS-EDDANVKWFK 401
              EY   AG  + S  L+V  P P  V ++L+  T   G+       +S      + W+K
Sbjct: 3215 AGEYTFVAGRNRSSVTLYVNAPEPPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYK 3274

Query: 402  NGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAA--------EYSVMTTGGQSSAKL-- 451
              + +  G K ++    +G+++ L++  A   DAA        +Y V TT    S ++  
Sbjct: 3275 EEQLLSTGFKCKF--LHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPE 3332

Query: 452  ------SVDLKPLKILTPLTDQTVNLGKEICLKCEIS-ENIPGKWTKNGLPVQESDRLKV 504
                   + + P  I+TPL D   + G+    +C +S  ++   W      ++ S   ++
Sbjct: 3333 VVSPDQEMPVYPPAIITPLQDTVTSEGQPARFQCRVSGTDLKVSWYSKDKKIKPSRFFRM 3392

Query: 505  VHKGRIHKLVIANALTEDEGDYVFAPD--AYNVTLPAKVHVIDPPKIILDGLDAD----- 557
                  ++L IA A  EDEG Y F        V+  A + +  P  I+ + ++ +     
Sbjct: 3393 TQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEAPESILHERIEQEIEMEM 3452

Query: 558  ----------NTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSG-RIRTESYPDS 606
                        + V  G+  +    I   P  +  W +  + I E     IR+  Y   
Sbjct: 3453 KAAPVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKY--I 3510

Query: 607  STLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDP 647
            S+L I   +  D G Y     NE G    +  + V +   P
Sbjct: 3511 SSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVTEAYPP 3551



 Score = 85.9 bits (211), Expect = 2e-16
 Identities = 102/444 (22%), Positives = 169/444 (38%), Gaps = 63/444 (14%)

Query: 721   AVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLE 780
             ++  + + KP  P  P            +  D V+  ++T+ W PP + G   +  Y+++
Sbjct: 23314 SIEIVTLDKPDPPKGP------------VKFDDVSAESITLSWNPPLYTGGCQITNYIVQ 23361

Query: 781   YCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEI 840
                  T  W V +   + +T   +T L T  +   R+ A N  G S     S PI+ +  
Sbjct: 23362 KRDTTTTVWDVVSAT-VARTTLKVTKLKTGTEYQFRIFAENRYGQSFA-LESDPIVAQYP 23419

Query: 841   IE---PPKIRIPRHL-KQTYIRRVGEAVN------LVIPFQGKPRPELTWKKDGAEIDKN 890
              +   PP       + K + + +  E VN      +    + K R  + W K    ++K 
Sbjct: 23420 YKEPGPPGTPFATAISKDSMVIQWHEPVNNGGSPVIGYHLERKERNSILWTK----VNKT 23475

Query: 891   QINIRNSETDTIIFIRKAERSHSG-KYDLQVKVDKFVETAS--------IDIQIIDRPGP 941
              I+      DT     KA+    G +Y+ +V  +  V            +     D PG 
Sbjct: 23476 IIH------DTQF---KAQNLEEGIEYEFRVYAENIVGVGKASKNSECYVARDPCDPPGT 23526

Query: 942   PQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTV-IEHYHRTSATIT 1000
             P+ + ++      + L WT P  DG + ITGY ++K D     W      +   T  T++
Sbjct: 23527 PEPIMVKR---NEITLQWTKPVYDGGSMITGYIVEKRDLPDGRWMKASFTNVIETQFTVS 23583

Query: 1001  ELVIGNEYYFRVFSENMCG-LSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQP 1059
              L     Y FRV ++N  G +S+ +  T         G I      E    S  P F   
Sbjct: 23584 GLTEDQRYEFRVIAKNAAGAISKPSDST---------GPITAKDEVELPRISMDPKFRDT 23634

Query: 1060  LVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPY 1119
             +V     AG    L   V G P P I W++    I +  R  + +      L ++     
Sbjct: 23635 IVVN---AGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRI 23691

Query: 1120  DGGTYCCKAVNDLGTVEIECKLEV 1143
             DGG Y  +A N  G+      ++V
Sbjct: 23692 DGGQYILRASNVAGSKSFPVNVKV 23715



 Score = 85.1 bits (209), Expect = 3e-16
 Identities = 128/595 (21%), Positives = 233/595 (39%), Gaps = 66/595 (11%)

Query: 84   LFIEKPQGGTVKVGEDITFIAKVKAEDLLRKPTIKWFKGKWMDLASKAGKHLQLKETFER 143
            +F +KP       G D+    ++          + W K +         K ++  + F+ 
Sbjct: 6459 VFTQKPSPVGALKGSDVILQCEISGTPPFE---VVWVKDR---------KQVRNSKKFKI 6506

Query: 144  HSRVYTFEMQIIKAKDNFAGNYRCEVTYKDKFDSCSFDLE-------VHESTGTTPNIDI 196
             S+ +   + I+  + +  G Y C+ T +   D+CS  ++       V + + T+  I  
Sbjct: 6507 TSKHFDTSLHILNLEASDVGEYHCKATNEVGSDTCSCSVKFKEPPRFVKKLSDTSTLIGD 6566

Query: 197  RSAFKRSGEGQEDAGELDFSGLLKRREVKQQEEEPQVDVWELLKNAKPSEYEKIA-FQYG 255
                +   EG +    +    L  R EV ++ E           N + S  + IA  Q G
Sbjct: 6567 AVELRAIVEGFQ---PISVVWLKDRGEVIRESE-----------NTRISFIDNIATLQLG 6612

Query: 256  ITDLRGMLKRLKRMRREE--KKSAAFAKILDPAYQVDKGGRVRFV---------VELADP 304
              +     K + +++ +   ++ +A   +L+PA  ++K   +            V    P
Sbjct: 6613 SPEASNSGKYICQIKNDAGMRECSAVLTVLEPARIIEKPEPMTVTTGNPFALECVVTGTP 6672

Query: 305  KLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYV----TAGDEKCSTEL 360
            +L  KW+K+G+E+   +K+          L I   +M+D   Y      + G   C+  +
Sbjct: 6673 ELSAKWFKDGRELSADSKHHITFINKVASLKIPCAEMSDKGLYSFEVKNSVGKSNCTVSV 6732

Query: 361  FVRE---PPIMVTKQLEDTTAYCGERVELECEVS-EDDANVKWFKNGEEIIPGPK--SRY 414
             V +   PP  + K L+D  A  G  V LEC VS     +V WF++G EI+ GPK  S +
Sbjct: 6733 HVSDRIVPPSFIRK-LKDVNAILGASVVLECRVSGSAPISVGWFQDGNEIVSGPKCQSSF 6791

Query: 415  RIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKE 474
               V      L+    T       + +    + SA L+V   P    TP + + +  G  
Sbjct: 6792 SENVCTLNLSLLEPSDTGIYTCVAANVAGSDECSAVLTVQEPPSFEQTPDSVEVLP-GMS 6850

Query: 475  ICLKCEISENIP--GKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDY--VFAP 530
            +     I    P   KW K    +   +   +  +  + +L +      + GDY  +   
Sbjct: 6851 LTFTSVIRGTPPFKVKWFKGSRELVPGESCNISLEDFVTELELFEVQPLESGDYSCLVTN 6910

Query: 531  DAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKA 590
            DA + +    + V +P   +    D     +V  G+ + LE   +G PP    W + D+ 
Sbjct: 6911 DAGSASCTTHLFVKEPATFVKRLAD----FSVETGSPIVLEATYTGTPPISVSWIK-DEY 6965

Query: 591  IMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFP 645
            ++  S R        S+ L I  +  +D   Y   ++NEAG+      V V++ P
Sbjct: 6966 LISQSERCSITMTEKSTILEILESTIEDYAQYSCLIENEAGQDICEALVSVLEPP 7020



 Score = 84.3 bits (207), Expect = 6e-16
 Identities = 105/451 (23%), Positives = 168/451 (37%), Gaps = 79/451 (17%)

Query: 722   VNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEY 781
             +  I + KP  P+ P            + +D +  T++T+ W PP+  G A L GYV+E 
Sbjct: 29824 IKVIILDKPGPPTGP------------IKIDEIDATSITISWEPPELDGGAPLSGYVVEQ 29871

Query: 782   CFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEII 841
                    W+  ++  + ++ F  T L    +   RV A N  G           L  E+I
Sbjct: 29872 RDAHRPGWLPVSES-VTRSTFKFTRLTEGNEYVFRVAATNRFGIGS-------YLQSEVI 29923

Query: 842   E-PPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTW---KKDGAE------IDKNQ 891
             E    IRIP           G    L I    +    LTW   + DG        +++ +
Sbjct: 29924 ECRSSIRIP-----------GPPETLQIFDVSRDGMTLTWYPPEDDGGSQVTGYIVERKE 29972

Query: 892   INIR-----NSETDTIIFIRKAERSHSGKYDLQVKVDKFVETAS--------IDIQIIDR 938
             +        N    T+   R    +   +Y+ +V       +          + +  I  
Sbjct: 29973 VRADRWVRVNKVPVTMTRYRSTGLTEGLEYEHRVTAINARGSGKPSRPSKPIVAMDPIAP 30032

Query: 939   PGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWF------TVIEHY 992
             PG PQ  ++ D    +V+L W+ P+D+G + +TGY I+       EW       T I  Y
Sbjct: 30033 PGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTKCNTTPTKIREY 30092

Query: 993   HRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSE 1052
                  T+T L  G EY FRV + N  G  E A        +    K+ +   Y D++  E
Sbjct: 30093 -----TLTHLPQGAEYRFRVLACNAGGPGEPAE-------VPGTVKVTEMLEYPDYELDE 30140

Query: 1053  APMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLE 1112
                  +     +   G    L   ++G P P   W K    I    R  + +++    L 
Sbjct: 30141 -----RYQEGIFVRQGGVIRLTIPIKGKPFPICKWTKEGQDI--SKRAMIATSETHTELV 30193

Query: 1113  IRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1143
             I++    D GTY     N  G   +  K+ V
Sbjct: 30194 IKEADRGDSGTYDLVLENKCGKKAVYIKVRV 30224



 Score = 82.8 bits (203), Expect = 2e-15
 Identities = 59/194 (30%), Positives = 92/194 (47%), Gaps = 21/194 (10%)

Query: 572   IPISGEPPPKAMWSRGDKAIMEGSGRIRTE-------SYPDSSTLVIDIAERDDSGVYHI 624
             + +  EPP         + ++E   R+ T        + PD +  V D+ E  +   + +
Sbjct: 14200 VDLKWEPPKNDGGRPIQRYVIEKKERLGTRWVKAGKTAGPDCNFRVTDVIEGTEVQ-FQV 14258

Query: 625   NLKNEAGEAHASIKVKVVDFPDPPVAPT------VTEVGDDWCIMNWEPPAYDGGSPILG 678
               +NEAG  H S   +++   DP   P+      VT+ G     + W+PP  +GGSPI+G
Sbjct: 14259 RAENEAGVGHPSEPTEILSIEDPTSPPSPPLDLHVTDAGRKHIAIAWKPPEKNGGSPIIG 14318

Query: 679   YFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVA----YEVRIFAVNAIGISKPSMPS 734
             Y +E     + +WMR+N    K+  F   K+ EGV     Y +R+ AVNAIG+S+PS  S
Sbjct: 14319 YHVEMCPVGTEKWMRVNSRPIKDLKF---KVEEGVVPDKEYVLRVRAVNAIGVSEPSEIS 14375

Query: 735   RPFVPLAVTSPPTL 748
                V       PT+
Sbjct: 14376 ENVVAKDPDCKPTI 14389



 Score = 77.4 bits (189), Expect = 7e-14
 Identities = 50/197 (25%), Positives = 94/197 (47%), Gaps = 14/197 (7%)

Query: 276  SAAFAKILDPAYQ-------VDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHK 328
            ++A   +++PA++       + +G       + + P ++ +W++NG+ ++P  ++  E +
Sbjct: 8736 ASAKLTVIEPAWERHLQDVTLKEGQTCTMTCQFSVPNVKSEWFRNGRILKPQGRHKTEVE 8795

Query: 329  GCQRILFINNCQMTDDSEYYVTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELEC 388
                 L I + +  D  +Y     D + S EL +   PI  TK++++      +    EC
Sbjct: 8796 HKVHKLTIADVRAEDQGQYTCKYEDLETSAELRIEAEPIQFTKRIQNIVVSEHQSATFEC 8855

Query: 389  EVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTT----- 443
            EVS DDA V W+K   E+    K  Y  R +G+ H + I   T  D   YSV+       
Sbjct: 8856 EVSFDDAIVTWYKGPTELTESQK--YNFRNDGRCHYMTIHNVTPDDEGVYSVIARLEPRG 8913

Query: 444  GGQSSAKLSVDLKPLKI 460
              +S+A+L +  K +K+
Sbjct: 8914 EARSTAELYLTTKEIKL 8930



 Score = 75.5 bits (184), Expect = 3e-13
 Identities = 105/447 (23%), Positives = 173/447 (38%), Gaps = 58/447 (12%)

Query: 721   AVNAIGISKPSMPSR-PFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVL 779
             A NA G +K  +  +    P  V  P   +   ++T   +T+ W  P + G A +  Y++
Sbjct: 28033 AKNASGSAKAEIKVKVQDTPGKVVGP---IRFTNITGEKMTLWWDAPLNDGCAPITHYII 28089

Query: 780   EYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVK- 838
             E        W +  +D  +   +T   L    +   RV AVN  G   P   S P++ + 
Sbjct: 28090 EKRETSRLAWALI-EDKCEAQSYTAIKLINGNEYQFRVSAVNKFGVGRP-LDSDPVVAQI 28147

Query: 839   --EIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRN 896
                + + P I  P ++        G ++ L        RPE      G+EI +  +  R 
Sbjct: 28148 QYTVPDAPGIPEPSNI-------TGNSITLTWA-----RPE---SDGGSEIQQYILERRE 28192

Query: 897   SE-TDTIIFIRKAERSHS----------GKYDLQVKVDKF--VETASIDIQII------D 937
              + T  +  I K   S +           +Y+  V  +    V  AS   ++I      +
Sbjct: 28193 KKSTRWVKVISKRPISETRFKVTGLTEGNEYEFHVMAENAAGVGPASGISRLIKCREPVN 28252

Query: 938   RPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTV-IEHYHRTS 996
              PGPP +VK+ D     V+L W+ P  DG   I GY I+       +W  V  E   +T 
Sbjct: 28253 PPGPPTVVKVTDTSKTTVSLEWSKPVFDGGMEIIGYIIEMCKADLGDWHKVNAEACVKTR 28312

Query: 997   ATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMF 1056
              T+T+L  G EY FRV + N  G  +   +T     I    ++    +  D +F +  + 
Sbjct: 28313 YTVTDLQAGEEYKFRVSAINGAGKGDSCEVT---GTIKAVDRLTAPELDIDANFKQTHVV 28369

Query: 1057  TQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKP 1116
                       AG +  L  + +G P P   W K    +    R  + +     TL +   
Sbjct: 28370 R---------AGASIRLFIAYQGRPTPTAVWSKPDSNL--SLRADIHTTDSFSTLTVENC 28418

Query: 1117  SPYDGGTYCCKAVNDLGTVEIECKLEV 1143
             +  D G Y     N+ G+  I   ++V
Sbjct: 28419 NRNDAGKYTLTVENNSGSKSITFTVKV 28445



 Score = 73.9 bits (180), Expect = 8e-13
 Identities = 64/235 (27%), Positives = 91/235 (38%), Gaps = 46/235 (19%)

Query: 939   PGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRT-SA 997
             P PP  V++ +   E + +TW PP  DG + I GY I+K  K    W    EH     + 
Sbjct: 14580 PDPPVDVEVHNPTAEAMTITWKPPLYDGGSKIMGYIIEKIAKGEERWKRCNEHLVPILTY 14639

Query: 998   TITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFT 1057
             T   L  G EY FRV +EN  G+SE +  T  +  +            +  D  +  + T
Sbjct: 14640 TAKGLEEGKEYQFRVRAENAAGISEPSRATPPTKAV------------DPIDAPKVILRT 14687

Query: 1058  QPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDD-------PRYRM-------- 1102
                V      G    L+ S+ G+P P ITW+K++  IV +       P  R         
Sbjct: 14688 SLEVKR----GDEIALDASISGSPYPTITWIKDENVIVPEEIKKRAAPLVRRRKGEVQEE 14743

Query: 1103  --------------FSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1143
                            S +G   L +R     D G Y  K  ND G  +  C + V
Sbjct: 14744 EPFVLPLTQRLSIDNSKKGESQLRVRDSLRPDHGLYMIKVENDHGIAKAPCTVSV 14798



 Score = 73.9 bits (180), Expect = 8e-13
 Identities = 59/203 (29%), Positives = 83/203 (40%), Gaps = 14/203 (6%)

Query: 933   IQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHY 992
             ++  + P PP  + I D+    V+L W  PK DG + ITGY I+   K S +W T I   
Sbjct: 20959 VKASEAPSPPDSLNIMDITKSTVSLAWPKPKHDGGSKITGYVIEAQRKGSDQW-THITTV 21017

Query: 993   HRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSE 1052
                   +  L  G EY F+V + N  G S      +ES  +     + +  +  + D   
Sbjct: 21018 KGLECVVRNLTEGEEYTFQVMAVNSAGRSAP----RESRPVI----VKEQTMLPELDLRG 21069

Query: 1053  APMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLE 1112
                  Q LV   A AG N  +   V G PKP +TW K    +    R    +      L 
Sbjct: 21070 ---IYQKLV--IAKAGDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILN 21124

Query: 1113  IRKPSPYDGGTYCCKAVNDLGTV 1135
             I +    D G Y   A N +G V
Sbjct: 21125 INECVRSDSGPYPLTARNIVGEV 21147



 Score = 73.2 bits (178), Expect = 1e-12
 Identities = 52/197 (26%), Positives = 86/197 (43%), Gaps = 13/197 (6%)

Query: 937   DRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTS 996
             ++P PP+ + + D    +  L W  P  DG + ITGY ++   K S  W     H  + +
Sbjct: 28544 EQPAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSDFWVEA-GHTKQLT 28602

Query: 997   ATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMF 1056
              T+  LV   EY FRV ++N  G SE       S+VI ++ +I           ++    
Sbjct: 28603 FTVERLVEKTEYEFRVKAKNDAGYSEPREAF--SSVIIKEPQIEPT--------ADLTGI 28652

Query: 1057  TQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKP 1116
             T  L+   A  G   T++  + G P PK+TW   ++ + +  R  + + +   TL ++  
Sbjct: 28653 TNQLITCKA--GSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVSITTTKDRTTLTVKDS 28710

Query: 1117  SPYDGGTYCCKAVNDLG 1133
                D G Y     N  G
Sbjct: 28711 MRGDSGRYFLTLENTAG 28727



 Score = 68.9 bits (167), Expect = 3e-11
 Identities = 135/688 (19%), Positives = 232/688 (33%), Gaps = 145/688 (21%)

Query: 2     PEPTKKEENEVPAP----APPPEEPSKEKEAGTTPAKDEEEVSPPSALPPGLGSRALERK 57
             PEP  K    V +P    +P P  P       T P   E+    P + PP +        
Sbjct: 32669 PEPRVKSPEAVKSPKRVKSPEPSHPKAVSPTETKPTPTEKVQHLPVSAPPKITQ------ 32722

Query: 58    DSDWTLVETPPGEEQAKQNANSQLSILFIEKPQGGTVKVGEDITFIAKVKAEDLLRKPTI 117
                                        F++       +  ++I  +  V    +LR   +
Sbjct: 32723 ---------------------------FLK------AEASKEIAKLTCVVESSVLRAKEV 32749

Query: 118   KWFKGKWMDLASKAGKHLQLKETFERH-SRVYTFEMQIIKAKDNFAGNYRCEVTYKDKFD 176
              W+K          GK L+    F+ H S   T+E++I    ++  G Y CE+       
Sbjct: 32750 TWYKD---------GKKLKENGHFQFHYSADGTYELKINNLTESDQGEYVCEI------- 32793

Query: 177   SCSFDLEVHESTGTTPNIDIRSAFKRSGEGQEDAGELDFSG---------LLKRREVKQQ 227
                                       SGEG      L F G         + K  E K+ 
Sbjct: 32794 --------------------------SGEGGTSKTNLQFMGQAFKSIHEKVSKISETKKS 32827

Query: 228   EEEPQVDVWELLKNAKPSEYEKIAFQYGITDLRGMLKRLKRMRREEKKSAAFAKILDPAY 287
             +++       + +  +P   E I+                       K      + D   
Sbjct: 32828 DQKTTEST--VTRKTEPKAPEPIS----------------------SKPVIVTGLQDTTV 32863

Query: 288   QVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEY 347
               D   +   V    +P+    W K+G+ I    KY          L I+    +D   Y
Sbjct: 32864 SSDSVAKFA-VKATGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLY 32922

Query: 348   YVT----AGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNG 403
               T    AG    S +L ++   I  T+  + +T    E    +  V +++ + K  ++ 
Sbjct: 32923 TCTVKNSAGSVSSSCKLTIKA--IKDTEAQKVSTQKTSEITPQKKAVVQEEISQKALRSE 32980

Query: 404   EEIIPGPKSRYRIRVEGKKHILIIEGATKADAA---EYSVMTTGGQSSAKLSVDLKP-LK 459
             E  +   KS+ ++ ++ +   ++I    K  AA   E S++      +++ S +++   +
Sbjct: 32981 EIKMSEAKSQEKLALKEEASKVLISEEVKKSAATSLEKSIVHEEITKTSQASEEVRTHAE 33040

Query: 460   ILTPLTDQTVNLGKEICLKCEISENIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANAL 519
             I    T  ++N G+ + LK  I+     KW  NG+ +  S+  +    G    L I  A 
Sbjct: 33041 IKAFSTQMSINEGQRLVLKANIAGATDVKWVLNGVELTNSEEYRYGVSGSDQTLTIKQAS 33100

Query: 520   TEDEGDYV--------FAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLE 571
               DEG                Y++TL  ++   D P  I        +  +  G  +   
Sbjct: 33101 HRDEGILTCISKTKEGIVKCQYDLTLSKELS--DAPAFI----SQPRSQNINEGQNVLFT 33154

Query: 572   IPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAG 631
               ISGEP P+  W + +  I   S  +      +  +L I  A   DSG Y I  KN  G
Sbjct: 33155 CEISGEPSPEIEWFKNNLPI-SISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRG 33213

Query: 632   EAHASIKVKVVDFPDPPVAPTVTEVGDD 659
             +  A+  + V+   + P    V     D
Sbjct: 33214 QCSATASLMVLPLVEEPSREVVLRTSGD 33241



 Score = 66.2 bits (160), Expect = 2e-10
 Identities = 94/408 (23%), Positives = 146/408 (35%), Gaps = 40/408 (9%)

Query: 742   VTSPPT-LLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKT 800
             +  PPT  +  D V+   VT  W PP++ G   +  YV+E     +  W+     +I +T
Sbjct: 21158 IPGPPTGPIKFDEVSSDFVTFSWDPPENDGGVPISNYVVEMRQTDSTTWVELATTVI-RT 21216

Query: 801   KFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQ-TYIRR 859
              +  T L T  +   RVKA N  G   P   S  I+      P K+  P    Q T + +
Sbjct: 21217 TYKATRLTTGLEYQFRVKAQNRYGVG-PGITSACIVANY---PFKVPGPPGTPQVTAVTK 21272

Query: 860   VGEAVNLVIPF------------QGKPRPELTWKKDGAEIDKNQINIRNSETDTIIF-IR 906
                 ++   P             + K R  + W+     +    I   +  TD I +  R
Sbjct: 21273 DSMTISWHEPLSDGGSPILGYHVERKERNGILWQTVSKALVPGNIFKSSGLTDGIAYEFR 21332

Query: 907   KAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDG 966
                 + +GK     K  K  E   + +  ID PG P  + I       V L W  P+  G
Sbjct: 21333 VIAENMAGKS----KPSKPSEPM-LALDPIDPPGKPVPLNITR---HTVTLKWAKPEYTG 21384

Query: 967   NAAITGYTIQKADKKSMEWFTV-IEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDAT 1025
                IT Y ++K D  +  W      +      T++ L     Y FRV ++N  G     +
Sbjct: 21385 GFKITSYIVEKRDLPNGRWLKANFSNILENEFTVSGLTEDAAYEFRVIAKNAAGAISPPS 21444

Query: 1026  MTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKI 1085
                ++     D +  K  V  D  F +  +           AG    L   V G P P +
Sbjct: 21445 EPSDAITCRDDVEAPKIKV--DVKFKDTVILK---------AGEAFRLEADVSGRPPPTM 21493

Query: 1086  TWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLG 1133
              W K+   +    +  +        L  +  +  D G Y   A N  G
Sbjct: 21494 EWSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDSGAYTLTATNPGG 21541



 Score = 64.7 bits (156), Expect = 5e-10
 Identities = 75/303 (24%), Positives = 129/303 (42%), Gaps = 19/303 (6%)

Query: 366   PIMVTKQLEDT----TAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGK 421
             P+   K+++D     + + G     EC VS   A   W K+G  I   PK  +R   +GK
Sbjct: 11114 PLKFVKEIKDIILTESEFVGSSAIFECLVSPSTAITTWMKDGSNIRESPK--HRFIADGK 11171

Query: 422   KHILIIEGATKADAAEYSVMTTGGQ----SSAKLSVDLKPLKILTPLTDQ-TVNLGKEIC 476
                L I     +DA EY+ +   G     S+AKL V+  P++ +  L ++ TV  G+ + 
Sbjct: 11172 DRKLHIIDVQLSDAGEYTCVLRLGNKEKTSTAKLVVEELPVRFVKTLEEEVTVVKGQPLY 11231

Query: 477   LKCEISENIPGKWTKNG-LPVQESDRLKVVHKGRIHKLVIANALTEDEGDY-VFAPDAYN 534
             L CE+++     W K+G + V++  R+     G +  L I +A   D G Y V   +A N
Sbjct: 11232 LSCELNKERDVVWRKDGKIVVEKPGRIVPGVIGLMRALTINDADDTDAGTYTVTVENANN 11291

Query: 535   VTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEG 594
             +   + V V++   +I D L        +      +      +  P   W +G   I   
Sbjct: 11292 LECSSCVKVVE---VIRDWLVKPIRDQHVKPKGTAIFACDIAKDTPNIKWFKGYDEI-PA 11347

Query: 595   SGRIRTESYPDSSTLVIDI--AERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPT 652
                 +TE   D + L + I  A  +D   Y + ++ +   A  ++  + V+   P    T
Sbjct: 11348 EPNDKTEILRDGNHLYLKIKNAMPEDIAEYAVEIEGKRYPAKLTLGEREVELLKPIEDVT 11407

Query: 653   VTE 655
             + E
Sbjct: 11408 IYE 11410



 Score = 63.5 bits (153), Expect = 1e-09
 Identities = 31/92 (33%), Positives = 43/92 (46%)

Query: 1054 PMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEI 1113
            P     L N   I G + TL C + G P P +TW +    I     +++    G+  L I
Sbjct: 943  PTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLMI 1002

Query: 1114 RKPSPYDGGTYCCKAVNDLGTVEIECKLEVKV 1145
            R+    D G + C AVN+ GTV   C L V+V
Sbjct: 1003 REAFAEDSGRFTCSAVNEAGTVSTSCYLAVQV 1034



 Score = 61.2 bits (147), Expect = 5e-09
 Identities = 33/100 (33%), Positives = 54/100 (54%), Gaps = 6/100 (6%)

Query: 938   RPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEH-YHRTS 996
             RP PP++ K+     E + + W PP+ DG  +ITGY ++K +K S  W  V +       
Sbjct: 18398 RPDPPEVTKVSK---EEMTVVWNPPEYDGGKSITGYFLEKKEKHSTRWVPVNKSAIPERR 18454

Query: 997   ATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARD 1036
               +  L+  +EY FRV +EN  G+ E +  ++   V+A+D
Sbjct: 18455 MKVQNLLPDHEYQFRVKAENEIGIGEPSLPSR--PVVAKD 18492



 Score = 59.7 bits (143), Expect = 2e-08
 Identities = 74/324 (22%), Positives = 129/324 (39%), Gaps = 19/324 (5%)

Query: 836  LVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQ--GKPRPELTWKKDGAEID----- 888
            L +E   P +   P  + +  ++++ E  ++V   Q  G P+P + WKK G  +      
Sbjct: 1069 LTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRY 1128

Query: 889  KNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIE 948
            K   N +  E   +I +  A+   +G+Y + V+ +K  ET S    +++      ++K +
Sbjct: 1129 KVSYNKQTGECKLVISMTFAD--DAGEYTIVVR-NKHGET-SASASLLEEADYELLMKSQ 1184

Query: 949  DVWGENVALTWTPPKDDGNAAITGYTIQKADKK-SMEWFTVIEHYHRTSATITELVIGNE 1007
                    +T    +        G+   + +K+   E   + +   + +  +   V   E
Sbjct: 1185 QEMLYQTQVTAFVQEPKVGETAPGFVYSEYEKEYEKEQALIRKKMAKDTVVVRTYVEDQE 1244

Query: 1008 YYFRVFSENMCGLSEDATM-TKESAVIARDGKIYKNPVYEDFDFSEAPM--FTQPLVNTY 1064
            ++   F E +    E   + T    ++  DG+     +  D   SEA    F   + N  
Sbjct: 1245 FHISSFEERLIKEIEYRIIKTTLEELLEEDGE---EKMAVDISESEAVESGFDSRIKNYR 1301

Query: 1065 AIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRM-FSNQGVCTLEIRKPSPYDGGT 1123
             + G   T +C + G P PKI W K+   I    RY+M F   G  +L I    P D G 
Sbjct: 1302 ILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPEDEGI 1361

Query: 1124 YCCKAVNDLGTVEIECKLEVKVIA 1147
            Y   A N  G      KL V+  A
Sbjct: 1362 YTAFASNIKGNAICSGKLYVEPAA 1385



 Score = 57.0 bits (136), Expect = 1e-07
 Identities = 43/167 (25%), Positives = 72/167 (43%), Gaps = 11/167 (6%)

Query: 370 TKQLEDTTAYCGERVELECEVSEDDA-NVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIE 428
           T+ L+      G     E  +S      V WF++G+ I        +I     +  L I 
Sbjct: 9   TQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKLTIP 68

Query: 429 GATKADAAEYSVMTTGGQSSAKLSVDL------KPLKILTPLTDQTVNLGKEICLKCEIS 482
             TKA++  YS+  T G   A  + +L       P   +  L   TV  G ++ L+  ++
Sbjct: 69  AVTKANSGRYSLKATNGSGQATSTAELLVKAETAPPNFVQRLQSMTVRQGSQVRLQVRVT 128

Query: 483 ENIPG---KWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDY 526
             IP    K+ ++G  +Q S   ++  +G ++ L+IA A  ED G Y
Sbjct: 129 -GIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTY 174



 Score = 56.6 bits (135), Expect = 1e-07
 Identities = 39/140 (27%), Positives = 56/140 (40%), Gaps = 9/140 (6%)

Query: 1010  FRVFSENMCGLSEDATM---TKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAI 1066
             F+   E +  +SE       T ES V  +       P+      S  P+    L +T   
Sbjct: 32811 FKSIHEKVSKISETKKSDQKTTESTVTRKTEPKAPEPI------SSKPVIVTGLQDTTVS 32864

Query: 1067  AGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCC 1126
             +   A       G P+P   W K+  AI    +Y++  ++G   LEI K    D G Y C
Sbjct: 32865 SDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTC 32924

Query: 1127  KAVNDLGTVEIECKLEVKVI 1146
                N  G+V   CKL +K I
Sbjct: 32925 TVKNSAGSVSSSCKLTIKAI 32944



 Score = 56.6 bits (135), Expect = 1e-07
 Identities = 74/348 (21%), Positives = 121/348 (34%), Gaps = 77/348 (22%)

Query: 872   GKPRPELTWKKDGAEIDKN-QINIRNSETDTIIFIRKAERSHSGKYD------------- 917
             G+PRP   W KDG  I +  +  +   +    + I K + S SG Y              
Sbjct: 32877 GEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSS 32936

Query: 918   --LQVKVDKFVETASIDIQIIDRPGPPQIVKIED------VWGENVALTWTPP------K 963
               L +K  K  E   +  Q      P +   +++      +  E + ++          K
Sbjct: 32937 CKLTIKAIKDTEAQKVSTQKTSEITPQKKAVVQEEISQKALRSEEIKMSEAKSQEKLALK 32996

Query: 964   DDGNAAITGYTIQKADKKSMEWFTVIEHYHRTS-------------ATITELVIGNEYYF 1010
             ++ +  +    ++K+   S+E   V E   +TS             A  T++ I NE   
Sbjct: 32997 EEASKVLISEEVKKSAATSLEKSIVHEEITKTSQASEEVRTHAEIKAFSTQMSI-NEGQR 33055

Query: 1011  RVFSENMCGLSE-----------------------DATMT------KESAVIARDGKIYK 1041
              V   N+ G ++                       D T+T      ++  ++    K  +
Sbjct: 33056 LVLKANIAGATDVKWVLNGVELTNSEEYRYGVSGSDQTLTIKQASHRDEGILTCISKTKE 33115

Query: 1042  NPVYEDFDF------SEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIV 1095
               V   +D       S+AP F     +     G N    C + G P P+I W KN + I 
Sbjct: 33116 GIVKCQYDLTLSKELSDAPAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPIS 33175

Query: 1096  DDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1143
                   +  ++ V +LEIR  S  D G Y  KA N  G       L V
Sbjct: 33176 ISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMV 33223



 Score = 54.7 bits (130), Expect = 5e-07
 Identities = 52/221 (23%), Positives = 77/221 (34%), Gaps = 45/221 (20%)

Query: 927  ETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWF 986
            +TA  D++++ RP P      E  W             DG   +  YT +          
Sbjct: 1472 QTARFDLKVVGRPMP------ETFWFH-----------DGQQIVNDYTHK---------- 1504

Query: 987  TVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYE 1046
             VI+     S  I      +   + V ++N  G S  + +    AV              
Sbjct: 1505 VVIKEDGTQSLIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAV-------------- 1550

Query: 1047 DFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDD--PRYRMFS 1104
              +    PMF + L N     G    +     GNP P I W+KN   IV    P+ R+  
Sbjct: 1551 --EHQVKPMFVEKLKNVNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEG 1608

Query: 1105 NQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVKV 1145
             +G   L+I      D   Y   A+N  G     CK+ V+V
Sbjct: 1609 TKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEV 1649



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 26/95 (27%), Positives = 48/95 (50%), Gaps = 1/95 (1%)

Query: 1051 SEAPMFTQPLVNTYAI-AGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVC 1109
            +E P F + L  +  + AG ++ L C + G+P+ ++ W +N+  +    +YRM     V 
Sbjct: 5420 TEPPKFVKKLEASKIVKAGDSSRLECKIAGSPEIRVVWFRNEHELPASDKYRMTFIDSVA 5479

Query: 1110 TLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVK 1144
             +++   S  D G + C+A N  G+     K+ VK
Sbjct: 5480 VIQMNNLSTEDSGDFICEAQNPAGSTSCSTKVIVK 5514



 Score = 51.2 bits (121), Expect = 6e-06
 Identities = 56/305 (18%), Positives = 122/305 (40%), Gaps = 22/305 (7%)

Query: 849   PRHLKQTYIRRVGEAVNLVIPFQ--GKPRPELTWKKDGAEID-KNQINIRNSETDTIIFI 905
             P  + Q   + + E  N++   +  G+P PE+ W K+   I   + ++I  S     + I
Sbjct: 33134 PAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEI 33193

Query: 906   RKAERSHSGKYDLQVKVDKFVETASIDIQIIDR-PGPPQIVKIEDVWGENVALTWTPPKD 964
             R A  S SGKY ++ K  +   +A+  + ++     P + V +      ++  +++    
Sbjct: 33194 RNASVSDSGKYTIKAKNFRGQCSATASLMVLPLVEEPSREVVLRTSGDTSLQGSFSSQSV 33253

Query: 965   DGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDA 1024
               +A+    +       S    T ++    ++ +++ +    E +  + S +  G+S   
Sbjct: 33254 QMSASKQEASFSSFSSSSASSMTEMKFASMSAQSMSSM---QESFVEMSSSSFMGISNMT 33310

Query: 1025  TMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAI-AGYNATLNCSVRGNPKP 1083
              +   ++ + + G                P   + L +  +I  G   T+ C+  G P P
Sbjct: 33311 QLESSTSKMLKAG------------IRGIPPKIEALPSDISIDEGKVLTVACAFTGEPTP 33358

Query: 1084  KITWM--KNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKL 1141
             ++TW     K+   +  R+ + +   + TL I      DGG Y     N+ G+      +
Sbjct: 33359 EVTWSCGGRKIHSQEQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNI 33418

Query: 1142  EVKVI 1146
              ++ I
Sbjct: 33419 HIRSI 33423



 Score = 48.9 bits (115), Expect = 3e-05
 Identities = 59/283 (20%), Positives = 97/283 (34%), Gaps = 70/283 (24%)

Query: 861  GEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQV 920
            GE+V L     G P P +TW ++  +I+                                
Sbjct: 957  GESVTLECHISGYPSPTVTWYREDYQIE-------------------------------- 984

Query: 921  KVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADK 980
                    +SID QI  + G  +++  E    ++   T +   + G  + + Y   +   
Sbjct: 985  --------SSIDFQITFQSGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQ--- 1033

Query: 981  KSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIY 1040
                   V E + + +  +TE     E   + F E+   +  D ++T+E A        Y
Sbjct: 1034 -------VSEEFEKETTAVTEKFTTEE---KRFVESRDVVMTDTSLTEEQAGPGEPAAPY 1083

Query: 1041 KNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRY 1100
                            T+P+V    + G +    C V GNPKP + W K+ V +    RY
Sbjct: 1084 --------------FITKPVVQKL-VEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRY 1128

Query: 1101 RMFSNQ--GVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKL 1141
            ++  N+  G C L I      D G Y     N  G       L
Sbjct: 1129 KVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL 1171



 Score = 47.4 bits (111), Expect = 8e-05
 Identities = 28/96 (29%), Positives = 44/96 (45%), Gaps = 2/96 (2%)

Query: 1051 SEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDD--PRYRMFSNQGV 1108
            ++AP FTQPL +   + G  AT    + G P P+++W ++   I     P  ++  + G 
Sbjct: 3    TQAPTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGR 62

Query: 1109 CTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVK 1144
              L I   +  + G Y  KA N  G      +L VK
Sbjct: 63   AKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVK 98



 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 36/105 (34%), Positives = 48/105 (45%), Gaps = 4/105 (3%)

Query: 537  LPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSG 596
            +PA V +   P  ++ GL     VTVI G  + LE  ISG P P   W R D  I E S 
Sbjct: 932  VPAPVEIPVTPPTLVSGL---KNVTVIEGESVTLECHISGYPSPTVTWYREDYQI-ESSI 987

Query: 597  RIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKV 641
              +       + L+I  A  +DSG +  +  NEAG    S  + V
Sbjct: 988  DFQITFQSGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAV 1032



 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 29/93 (31%), Positives = 42/93 (45%), Gaps = 3/93 (3%)

Query: 1054  PMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIV---DDPRYRMFSNQGVCT 1110
             P FT PL N  A  G N     ++  +P+P +TW K+   I    +D +Y   S++G+  
Sbjct: 31690 PEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQ 31749

Query: 1111  LEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1143
             L I   +  D   Y   A N  G    + KL V
Sbjct: 31750 LTINSVTTDDDAEYTVVARNKYGEDSCKAKLTV 31782



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 29/100 (29%), Positives = 49/100 (49%), Gaps = 5/100 (5%)

Query: 939   PGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEH--YHRTS 996
             P  P    + +V  ++  +TW  P D G   IT Y ++K +  S  W  V +   +  T 
Sbjct: 17012 PDAPDQPIVTEVTKDSALVTWNKPHDGGKP-ITNYILEKRETMSKRWARVTKDPIHPYTK 17070

Query: 997   ATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARD 1036
               + +L+ G +Y FRV +EN  G+ + +  +K   V A+D
Sbjct: 17071 FRVPDLLEGCQYEFRVSAENEIGIGDPSPPSK--PVFAKD 17108



 Score = 45.1 bits (105), Expect = 4e-04
 Identities = 120/582 (20%), Positives = 208/582 (35%), Gaps = 92/582 (15%)

Query: 341  MTDDSEYYVTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDA-NVKW 399
            MTD S     AG  + +   F+ +P  +V K +E      G  V   C+V  +   +V W
Sbjct: 1064 MTDTSLTEEQAGPGEPAAPYFITKP--VVQKLVE------GGSVVFGCQVGGNPKPHVYW 1115

Query: 400  FKNGEEIIPGPKSRYRIRVEGKKHI----LIIEGATKADAAEYSVMTTG--GQSSAKLSV 453
             K+G  +  G    YR +V   K      L+I      DA EY+++     G++SA  S+
Sbjct: 1116 KKSGVPLTTG----YRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL 1171

Query: 454  DLKPLKILTPLTDQTVNLGKEICL---KCEISENIPGKWTKNGLPVQESDRLKVVHKGRI 510
              +    L   + Q +    ++     + ++ E  PG +  +    +      ++ K   
Sbjct: 1172 LEEADYELLMKSQQEMLYQTQVTAFVQEPKVGETAPG-FVYSEYEKEYEKEQALIRKKMA 1230

Query: 511  HKLVIANALTEDEGDYVFAPDA----------YNVTLPAKVHVIDPPKIILD-------- 552
               V+     ED+  ++ + +              TL   +      K+ +D        
Sbjct: 1231 KDTVVVRTYVEDQEFHISSFEERLIKEIEYRIIKTTLEELLEEDGEEKMAVDISESEAVE 1290

Query: 553  -GLDAD-NTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDS-STL 609
             G D+      ++ G  +     +SG P PK  W +  K I  G  R + +   D  ++L
Sbjct: 1291 SGFDSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGE-RYQMDFLQDGRASL 1349

Query: 610  VIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPA 669
             I +   +D G+Y     N  G A  S K+ V      P AP    +G    I   EP  
Sbjct: 1350 RIPVVLPEDEGIYTAFASNIKGNAICSGKLYV-----EPAAP----LGAPTYIPTLEP-- 1398

Query: 670  YDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISK 729
                       + R +  S R +  +          P +M        R+     +  + 
Sbjct: 1399 -----------VSRIRSLSPRSVSRSPIRMSPARMSPARMSPARMSPARMSPGRRLEETD 1447

Query: 730  PSMPSRPFVPLAVTSPPTLLTVDSVT---DTTVTMRWRPPD---HIGAAGLDGYVLEYCF 783
             S   R + P+ V  P +   ++  T   D  V  R  P     H G   ++ Y  +   
Sbjct: 1448 ESQLERLYKPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVI 1507

Query: 784  --EGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEII 841
              +GT+  I+      D  ++T+              A N AG S     S  + V+ + 
Sbjct: 1508 KEDGTQSLIIVPATPSDSGEWTVV-------------AQNRAGRSS---ISVILTVEAVE 1551

Query: 842  EPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKD 883
               K      LK   I+  G  + + +   G P P++ W K+
Sbjct: 1552 HQVKPMFVEKLKNVNIKE-GSRLEMKVRATGNPNPDIVWLKN 1592



 Score = 45.1 bits (105), Expect = 4e-04
 Identities = 53/231 (22%), Positives = 95/231 (41%), Gaps = 17/231 (7%)

Query: 419  EGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLK 478
            E + H L IE   +++  E            +LS   +P+ ++  + +QTV    +   +
Sbjct: 8618 EEETHRLEIEEIERSERDEKEFEELVSFIQQRLS-QTEPVTLIKDIENQTVLKDNDAVFE 8676

Query: 479  CEISENIPG---KWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNV 535
             +I  N P     W K    ++ SD+ ++   G  H L + N   +D+G+Y      +  
Sbjct: 8677 IDIKINYPEIKLSWYKGTEKLEPSDKFEISIDGDRHTLRVKNCQLKDQGNYRLVCGPHIA 8736

Query: 536  TLPAKVHVIDPP--KIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIME 593
            +  AK+ VI+P   + + D       VT+  G    +    S  P  K+ W R  + I++
Sbjct: 8737 S--AKLTVIEPAWERHLQD-------VTLKEGQTCTMTCQFS-VPNVKSEWFRNGR-ILK 8785

Query: 594  GSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDF 644
              GR +TE       L I     +D G Y    ++    A   I+ + + F
Sbjct: 8786 PQGRHKTEVEHKVHKLTIADVRAEDQGQYTCKYEDLETSAELRIEAEPIQF 8836



 Score = 44.7 bits (104), Expect = 5e-04
 Identities = 62/284 (21%), Positives = 105/284 (36%), Gaps = 51/284 (17%)

Query: 876  PELT--WKKDGAEID-KNQINIRNSETDTIIFIRKAERSHSGKYDL----QVKVDK-FVE 927
            P++T  W KD  E+   ++I I+  +    + I     S +GKY +     V   K FVE
Sbjct: 3084 PDITVQWMKDDQELQITDRIKIQKEKYVHRLLIPSTRMSDAGKYTVVAGGNVSTAKLFVE 3143

Query: 928  TASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNA------AITGYTIQKADKK 981
               + I+ I +       +++ +  +   + +   +DD +A          + +Q+  K 
Sbjct: 3144 GRDVRIRSIKK-------EVQVIEKQRAVVEFEVNEDDVDAHWYKDGIEINFQVQERHK- 3195

Query: 982  SMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYK 1041
                + V    HR   + T      EY F V   N   ++                 +Y 
Sbjct: 3196 ----YVVERRIHRMFISETRQSDAGEYTF-VAGRNRSSVT-----------------LYV 3233

Query: 1042 NPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYR 1101
            N         E P   Q L      +G  A     + G P+PKI+W K +  +    + +
Sbjct: 3234 NA-------PEPPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCK 3286

Query: 1102 MFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVKV 1145
               +    TL + +  P D   Y C+A ND G       L V+V
Sbjct: 3287 FLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEV 3330



 Score = 44.3 bits (103), Expect = 7e-04
 Identities = 29/98 (29%), Positives = 51/98 (52%), Gaps = 1/98 (1%)

Query: 559 TVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDD 618
           ++TV  G+++RL++ ++G P P   + R D A ++ S   +     D  +L+I  A  +D
Sbjct: 112 SMTVRQGSQVRLQVRVTGIPTPVVKFYR-DGAEIQSSLDFQISQEGDLYSLLIAEAYPED 170

Query: 619 SGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEV 656
           SG Y +N  N  G A ++ ++ V    + P   T T V
Sbjct: 171 SGTYSVNATNSVGRATSTAELLVQGEEEVPAKKTKTIV 208



 Score = 44.3 bits (103), Expect = 7e-04
 Identities = 64/320 (20%), Positives = 110/320 (34%), Gaps = 40/320 (12%)

Query: 340   QMTDDSEYYVTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEV-SEDDANVK 398
             Q T + +Y      E  S + F  +    +T ++      CG+       V S+  A VK
Sbjct: 32353 QKTSERKY------EVLSQQPFTLDHAPRITLRMRSHRVPCGQNTRFILNVQSKPTAEVK 32406

Query: 399   WFKNGEEIIPGPKSRYRIRVEGKKHILIIEGAT-------------KADAAEYSVM-TTG 444
             W+ NG E+    K  Y     G   + I++  T             K +A++Y+ +  TG
Sbjct: 32407 WYHNGVELQESSKIHYT-NTSGVLTLEILDCHTDDSGTYRAVCTNYKGEASDYATLDVTG 32465

Query: 445   GQSSAKLSV---DLKPLKILTPLTDQTVNLGKEICLKCEISENIPGKWTKNGLPVQESDR 501
             G  +   S    +  P  +   LT              E+  +   +  K+ +       
Sbjct: 32466 GDYTTYASQRRDEEVPRSVFPELTRTEAYAVSSFKKTSEMEASSSVREVKSQMTETRESL 32525

Query: 502   LKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVT 561
                 H       + + AL E   +          TL A++            L    ++T
Sbjct: 32526 SSYEHSASAE--MKSAALEEKSLEEKSTTRKIKTTLAARI------------LTKPRSMT 32571

Query: 562   VIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGV 621
             V  G   R      GEP P   W R  + ++  S R +  +    ST  I   +  D G 
Sbjct: 32572 VYEGESARFSCDTDGEPVPTVTWLRKGQ-VLSTSARHQVTTTKYKSTFEISSVQASDEGN 32630

Query: 622   YHINLKNEAGEAHASIKVKV 641
             Y + ++N  G+  A   + +
Sbjct: 32631 YSVVVENSEGKQEAEFTLTI 32650



 Score = 43.9 bits (102), Expect = 9e-04
 Identities = 94/440 (21%), Positives = 160/440 (36%), Gaps = 71/440 (16%)

Query: 271  REEKKSAAFAKILDPAYQVDKGGRVRFVVELAD-PKLEVKWYKNGQEIRPSTKYIFEHKG 329
            ++EK+        +P  +V +G   RF   +   P+ +V WY NGQ IR S ++   + G
Sbjct: 1835 QKEKQKPDIVLYPEPV-RVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRVRYDG 1893

Query: 330  CQRILFINNCQMTDDSEYYVTAG------DEKCSTELFVREP------------------ 365
                L I +C+  D  E  VTA       + K   E+  RE                   
Sbjct: 1894 I-HYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQREDFRSVLRRAPEPRPEFHVH 1952

Query: 366  --------------PIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGE-----EI 406
                          P+  T+  E       ER+  E    E +     FK        E 
Sbjct: 1953 EPGKLQFEVQKVDRPVDTTETKEVVKLKRAERITHEKVPEESEELRSKFKRRTEEGYYEA 2012

Query: 407  IPGPKSRYRIRVEGKKHIL-------------IIEGATKADAAEYSV-MTTGGQSSAKLS 452
            I   + + R + E  + +L             + E   KA A E  + + T      +LS
Sbjct: 2013 ITAVELKSRKKDESYEELLRKTKDELLHWTKELTEEEKKALAEEGKITIPTFKPDKIELS 2072

Query: 453  VDLKPLKILTPLTDQTVNLGKEICLKCEI--SENIPGKWTKNGLPVQESDRLK-VVHKGR 509
              ++  KI   +  QTV  G +   +  +    +   +W KNG+ ++ SDR+     +  
Sbjct: 2073 PSMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDN 2132

Query: 510  IHKLVIANALTEDEGDYVFAPDAYNVTLPAKVH---VIDPPKIILDGLDADNTVTVIAGN 566
            + +LVI +   ED    +    A N+      H   ++   ++I    +  + V      
Sbjct: 2133 VCELVIRDVTAEDSASIMV--KAINIAGETSSHAFLLVQAKQLITFTQELQDVVAKEKDT 2190

Query: 567  KLRLEIPISGEPPPKAMWSRGDKAIMEGSG-RIRTE-SYPDSSTLVIDIAERDDSGVYHI 624
                E   S EP  K  W +    + EG   R+ ++      S L ID ++ +D     +
Sbjct: 2191 MATFECETS-EPFVKVKWYKDGMEVHEGDKYRMHSDRKVHFLSILTIDTSDAEDYSCVLV 2249

Query: 625  NLKNEAGEAHASIKVKVVDF 644
              +N    A   ++  VV+F
Sbjct: 2250 EDENVKTTAKLIVEGAVVEF 2269



 Score = 43.9 bits (102), Expect = 9e-04
 Identities = 26/79 (32%), Positives = 37/79 (46%), Gaps = 1/79 (1%)

Query: 1066 IAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYC 1125
            + G  A   C V G P+PK+ W  N   I    R+R+    G+  L+I     YD G   
Sbjct: 1853 LEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRV-RYDGIHYLDIVDCKSYDTGEVK 1911

Query: 1126 CKAVNDLGTVEIECKLEVK 1144
              A N  G +E + KLE++
Sbjct: 1912 VTAENPEGVIEHKVKLEIQ 1930



 Score = 43.9 bits (102), Expect = 9e-04
 Identities = 59/286 (20%), Positives = 102/286 (35%), Gaps = 24/286 (8%)

Query: 861   GEAVNLVIPFQGKPRPELTWKKDGAEI-DKNQINIRNSETDTIIFIRKAERSHSGKYDLQ 919
             G+    ++  Q KP  E+ W  +G E+ + ++I+  N+     + I       SG Y  +
Sbjct: 32388 GQNTRFILNVQSKPTAEVKWYHNGVELQESSKIHYTNTSGVLTLEILDCHTDDSGTY--R 32445

Query: 920   VKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKAD 979
                  +   AS D   +D  G            E V  +  P      A    Y +    
Sbjct: 32446 AVCTNYKGEAS-DYATLDVTGGDYTTYASQRRDEEVPRSVFPELTRTEA----YAVSSFK 32500

Query: 980   KKS-MEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGK 1038
             K S ME  + +       + +TE             E++      A+   +SA +     
Sbjct: 32501 KTSEMEASSSVRE---VKSQMTET-----------RESLSSYEHSASAEMKSAALEEKSL 32546

Query: 1039  IYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDP 1098
               K+   +      A + T+P   T    G +A  +C   G P P +TW++    +    
Sbjct: 32547 EEKSTTRKIKTTLAARILTKPRSMT-VYEGESARFSCDTDGEPVPTVTWLRKGQVLSTSA 32605

Query: 1099  RYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVK 1144
             R+++ + +   T EI      D G Y     N  G  E E  L ++
Sbjct: 32606 RHQVTTTKYKSTFEISSVQASDEGNYSVVVENSEGKQEAEFTLTIQ 32651



 Score = 43.5 bits (101), Expect = 0.001
 Identities = 61/263 (23%), Positives = 104/263 (39%), Gaps = 35/263 (13%)

Query: 286   AYQVDKGGRVRFVVEL-ADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDD 344
             +++V  G   RF++ + + P  EVKWY NG E++ S+K  + +      L I +C  TDD
Sbjct: 32382 SHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESSKIHYTNTSGVLTLEILDCH-TDD 32440

Query: 345   SEYY------------------VTAGD-EKCSTELFVREPPIMVTKQLEDTTAYCGERVE 385
             S  Y                  VT GD    +++    E P  V  +L  T AY     +
Sbjct: 32441 SGTYRAVCTNYKGEASDYATLDVTGGDYTTYASQRRDEEVPRSVFPELTRTEAYAVSSFK 32500

Query: 386   LECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGG 445
                E+ E  ++V+  K+         +  R  +   +H      + +  +A     +   
Sbjct: 32501 KTSEM-EASSSVREVKS-------QMTETRESLSSYEH----SASAEMKSAALEEKSLEE 32548

Query: 446   QSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCEI-SENIPG-KWTKNGLPVQESDRLK 503
             +S+ +        +ILT     TV  G+     C+   E +P   W + G  +  S R +
Sbjct: 32549 KSTTRKIKTTLAARILTKPRSMTVYEGESARFSCDTDGEPVPTVTWLRKGQVLSTSARHQ 32608

Query: 504   VVHKGRIHKLVIANALTEDEGDY 526
             V          I++    DEG+Y
Sbjct: 32609 VTTTKYKSTFEISSVQASDEGNY 32631



 Score = 43.1 bits (100), Expect = 0.002
 Identities = 41/170 (24%), Positives = 67/170 (39%), Gaps = 16/170 (9%)

Query: 489  WTKNGLPVQESDRLKVVHK-GRIHKLVIANALTEDEGDYVFAPD--------AYNVTLPA 539
            W  +G  +      KVV K      L+I  A   D G++             +  +T+ A
Sbjct: 1490 WFHDGQQIVNDYTHKVVIKEDGTQSLIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEA 1549

Query: 540  KVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGS-GRI 598
              H + P  +     +    V +  G++L +++  +G P P  +W +    I+     +I
Sbjct: 1550 VEHQVKPMFV-----EKLKNVNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKI 1604

Query: 599  RTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKV-VDFPDP 647
            R E     + L ID     DS  Y     N+AG      KV V V+F +P
Sbjct: 1605 RIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEVEFAEP 1654



 Score = 43.1 bits (100), Expect = 0.002
 Identities = 67/327 (20%), Positives = 116/327 (35%), Gaps = 65/327 (19%)

Query: 369   VTKQLEDTTAYCGERVELECEVSEDDAN--VKWFKNGEEIIPGPKSRYRIRVEGKKHILI 426
             V+ Q+       G  V+  C++   D +  V W+    ++    K  Y I  E    IL 
Sbjct: 31570 VSGQIMHAVGEEGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEK--YEITYEDGVAILY 31627

Query: 427   IEGATKADAAEY--SVMTTGGQSSAKLSVDLK---------------------------- 456
             ++  TK D   Y   V+   G+ S+   + +K                            
Sbjct: 31628 VKDITKLDDGTYRCKVVNDYGEDSSYAELFVKGVREVYDYYCRRTMKKIKRRTDTMRLLE 31687

Query: 457   -PLKILTPLTDQTVNLGKEICLKCEISENIPGK--WTKNGLPVQESDRLKVV----HKGR 509
              P +   PL ++T  +G+ +     I+ +      W K+G  ++  D  K       KG 
Sbjct: 31688 RPPEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKG- 31746

Query: 510   IHKLVIANALTEDEGDYV------FAPDAYNVTLPAKVHVIDPP---------KIILDGL 554
             +++L I +  T+D+ +Y       +  D+    L   +H   PP         K +L   
Sbjct: 31747 LYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVTLH--PPPTDSTLRPMFKRLLANA 31804

Query: 555   DADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIA 614
             +         G  +  EI +SG PPP   W +  + +  G          D   L I   
Sbjct: 31805 ECQE------GQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALHIRDT 31858

Query: 615   ERDDSGVYHINLKNEAGEAHASIKVKV 641
               +D+G Y +   N AG       ++V
Sbjct: 31859 LPEDTGYYRVTATNTAGSTSCQAHLQV 31885



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 33/111 (29%), Positives = 46/111 (41%), Gaps = 5/111 (4%)

Query: 1028 KESAVIARDGKI----YKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKP 1083
            +E   +A +GKI    +K    E     EAP   + + +     G +A     V G P P
Sbjct: 2048 EEKKALAEEGKITIPTFKPDKIELSPSMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDP 2107

Query: 1084 KITWMKNKVAIVDDPR-YRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLG 1133
            +  W KN V I    R Y  +    VC L IR  +  D  +   KA+N  G
Sbjct: 2108 ECEWYKNGVKIERSDRIYWYWPEDNVCELVIRDVTAEDSASIMVKAINIAG 2158



 Score = 42.0 bits (97), Expect = 0.003
 Identities = 27/93 (29%), Positives = 41/93 (44%), Gaps = 2/93 (2%)

Query: 1054 PMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEI 1113
            P F     +     G  A   C+V G P  +  W K+  A+   P +R+   +    LE+
Sbjct: 3551 PTFLSRPKSLTTFVGKAAKFICTVTGTPVIETIWQKDGAALSPSPNWRISDAENKHILEL 3610

Query: 1114 RKPSPYDGGTYCCKAVNDLGTVEIECKLEVKVI 1146
               +  D G Y CKA N  G  +I C+ E+ +I
Sbjct: 3611 SNLTIQDRGVYSCKASNKFG-ADI-CQAELIII 3641



 Score = 40.0 bits (92), Expect = 0.013
 Identities = 44/211 (20%), Positives = 95/211 (45%), Gaps = 28/211 (13%)

Query: 270  RREEKKSAAFAKILDPAYQVD-------KGGRVRFVVELAD-PKLEVKWYKNGQEIRP-- 319
            R EE   +   ++  P + +        +G   RF +++   P  E  W+ +GQ+I    
Sbjct: 1442 RLEETDESQLERLYKPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDY 1501

Query: 320  STKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTELFV--------REPPIMVTK 371
            + K + +  G Q ++ +     +D  E+ V A +    + + V         +   M  +
Sbjct: 1502 THKVVIKEDGTQSLIIVP-ATPSDSGEWTVVAQNRAGRSSISVILTVEAVEHQVKPMFVE 1560

Query: 372  QLEDTTAYCGERVELECEVSED-DANVKWFKNGEEIIPGPKSRY-RIRVEGKK--HILII 427
            +L++     G R+E++   + + + ++ W KN + I+P    +Y +IR+EG K    L I
Sbjct: 1561 KLKNVNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVP---HKYPKIRIEGTKGEAALKI 1617

Query: 428  EGATKADAAEY--SVMTTGGQSSAKLSVDLK 456
            +     D+A Y  + +   G+ + +  V+++
Sbjct: 1618 DSTVSQDSAWYTATAINKAGRDTTRCKVNVE 1648



 Score = 39.7 bits (91), Expect = 0.017
 Identities = 25/98 (25%), Positives = 37/98 (37%)

Query: 1046  EDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSN 1105
             + F    AP  T  + +     G N     +V+  P  ++ W  N V + +  +    + 
Sbjct: 32366 QPFTLDHAPRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESSKIHYTNT 32425

Query: 1106  QGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1143
              GV TLEI      D GTY     N  G       L+V
Sbjct: 32426 SGVLTLEILDCHTDDSGTYRAVCTNYKGEASDYATLDV 32463



 Score = 39.3 bits (90), Expect = 0.022
 Identities = 58/327 (17%), Positives = 107/327 (32%), Gaps = 45/327 (13%)

Query: 861  GEAVNLVIPFQGKPRPELTWKKDGAEIDKN---QINIRNSETDTIIFIRKAERSHSGKYD 917
            G+     +   G+P PE  W  DG +I  +   ++ I+   T ++I +  A  S SG++ 
Sbjct: 1471 GQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLIIV-PATPSDSGEWT 1529

Query: 918  L--QVKVDKFVETASIDIQIIDRPGPPQIV----------------KIEDVWGENVALTW 959
            +  Q +  +   +  + ++ ++    P  V                K+      N  + W
Sbjct: 1530 VVAQNRAGRSSISVILTVEAVEHQVKPMFVEKLKNVNIKEGSRLEMKVRATGNPNPDIVW 1589

Query: 960  TPPKD------------DGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNE 1007
                D            +G        I     +   W+T     ++     T   +  E
Sbjct: 1590 LKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATA-INKAGRDTTRCKVNVE 1648

Query: 1008 YYFR--------VFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQP 1059
              F         +         E A    E   +    + ++     D +  + P F + 
Sbjct: 1649 VEFAEPEPERKLIIPRGTYRAKEIAAPELEPLHLRYGQEQWEEGDLYDKEKQQKPFFKKK 1708

Query: 1060 LVNTYAIAGYNATLNCSVR--GNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPS 1117
            L +        A   C +   G+P   + W+ +   +    R RM +  G C+L+     
Sbjct: 1709 LTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRMINEFGYCSLDYGVAY 1768

Query: 1118 PYDGGTYCCKAVNDLGTVEIECKLEVK 1144
              D G   C+A N  GT      L VK
Sbjct: 1769 SRDSGIITCRATNKYGTDHTSATLIVK 1795



 Score = 38.9 bits (89), Expect = 0.028
 Identities = 44/162 (27%), Positives = 69/162 (42%), Gaps = 13/162 (8%)

Query: 304 PKLEVKWYKNGQEIRPST--KYIFEHKGCQRILFINNCQMTDDSEYYVTA----GDEKCS 357
           P  EV W+++GQ I  ST           +  L I      +   Y + A    G    +
Sbjct: 33  PVPEVSWFRDGQVISTSTLPGVQISFSDGRAKLTIPAVTKANSGRYSLKATNGSGQATST 92

Query: 358 TELFVR---EPPIMVTKQLEDTTAYCGERVELECEVSE-DDANVKWFKNGEEIIPGPKSR 413
            EL V+    PP  V ++L+  T   G +V L+  V+      VK++++G EI       
Sbjct: 93  AELLVKAETAPPNFV-QRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEI--QSSLD 149

Query: 414 YRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDL 455
           ++I  EG  + L+I  A   D+  YSV  T     A  + +L
Sbjct: 150 FQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAEL 191



 Score = 38.1 bits (87), Expect = 0.048
 Identities = 27/98 (27%), Positives = 41/98 (41%), Gaps = 3/98 (3%)

Query: 1049  DFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGV 1108
             D +  PMF + L N     G +      V G P P + W K+   +   P   +  ++G+
Sbjct: 31790 DSTLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEII-HEGL 31848

Query: 1109  --CTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVK 1144
                 L IR   P D G Y   A N  G+   +  L+V+
Sbjct: 31849 DYYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQVE 31886



 Score = 37.7 bits (86), Expect = 0.063
 Identities = 26/83 (31%), Positives = 34/83 (40%), Gaps = 5/83 (6%)

Query: 289   VDKGGRVRFVVELAD-PKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEY 347
             V  G  VRF   +   P    KW  +G EI+    Y  E      +L I NC   D  EY
Sbjct: 17522 VKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEY 17581

Query: 348   YVT----AGDEKCSTELFVREPP 366
              +T    AG +  +  L V + P
Sbjct: 17582 QITVSNAAGSKTVAVHLTVLDVP 17604



 Score = 37.7 bits (86), Expect = 0.063
 Identities = 19/65 (29%), Positives = 31/65 (47%)

Query: 1084  KITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1143
             ++TW      + +  +Y +    GV  L ++  +  D GTY CK VND G      +L V
Sbjct: 31599 QVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTYRCKVVNDYGEDSSYAELFV 31658

Query: 1144  KVIAQ 1148
             K + +
Sbjct: 31659 KGVRE 31663



 Score = 37.0 bits (84), Expect = 0.11
 Identities = 25/94 (26%), Positives = 40/94 (42%), Gaps = 1/94 (1%)

Query: 1054 PMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYR-MFSNQGVCTLE 1112
            P+F    V+   + G  A  +  V G P P+  W  +   IV+D  ++ +    G  +L 
Sbjct: 1457 PVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLI 1516

Query: 1113 IRKPSPYDGGTYCCKAVNDLGTVEIECKLEVKVI 1146
            I   +P D G +   A N  G   I   L V+ +
Sbjct: 1517 IVPATPSDSGEWTVVAQNRAGRSSISVILTVEAV 1550



 Score = 36.2 bits (82), Expect = 0.18
 Identities = 45/250 (18%), Positives = 92/250 (36%), Gaps = 31/250 (12%)

Query: 880   WKKDGAEIDKN-QINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDR 938
             W KDG EI  + + +I+      I+ I+KA+    G+Y      DK     +++ ++I  
Sbjct: 11694 WFKDGEEIVPSPKYSIKADGLRRILKIKKADLKDKGEYVCDCGTDKTKANVTVEARLIKV 11753

Query: 939   PGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSAT 998
               P   V++      +  +  + P   G   + G  +                   T++ 
Sbjct: 11754 EKPLYGVEVFVGETAHFEIELSEPDVHGQWKLKGQPL-------------------TASP 11794

Query: 999   ITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQ 1058
               E++   + +  +      G++ + +    +A  A + K+ + P+          +F  
Sbjct: 11795 DCEIIEDGKKHILILHNCQLGMTGEVSFQAANAKSAANLKVKELPL----------IFIT 11844

Query: 1059  PLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSP 1118
             PL +        A   C V   PK    W+K    I  D R+ +  +    ++ I+  + 
Sbjct: 11845 PLSDVKVFEKDEAKFECEVSREPK-TFRWLKGTQEITGDDRFELIKDGTKHSMVIKSAAF 11903

Query: 1119  YDGGTYCCKA 1128
              D   Y  +A
Sbjct: 11904 EDEAKYMFEA 11913



 Score = 36.2 bits (82), Expect = 0.18
 Identities = 39/146 (26%), Positives = 56/146 (38%), Gaps = 11/146 (7%)

Query: 301   LADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTEL 360
             L  PK  V W K  Q ++ + +  FE      IL IN C  +D   Y +TA +       
Sbjct: 21090 LGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLTARN------- 21142

Query: 361   FVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEG 420
              V E   ++T Q+ D        ++ + EVS D     W    E     P S Y + +  
Sbjct: 21143 IVGEVGDVITIQVHDIPGPPTGPIKFD-EVSSDFVTFSW-DPPENDGGVPISNYVVEMRQ 21200

Query: 421   KKHILIIEGATKADAAEYSV--MTTG 444
                   +E AT      Y    +TTG
Sbjct: 21201 TDSTTWVELATTVIRTTYKATRLTTG 21226



 Score = 35.8 bits (81), Expect = 0.24
 Identities = 25/91 (27%), Positives = 42/91 (46%), Gaps = 1/91 (1%)

Query: 559 TVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDS-STLVIDIAERD 617
           +V V+ G+    E  ISG P P+  W R  + I   +      S+ D  + L I    + 
Sbjct: 14  SVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKLTIPAVTKA 73

Query: 618 DSGVYHINLKNEAGEAHASIKVKVVDFPDPP 648
           +SG Y +   N +G+A ++ ++ V     PP
Sbjct: 74  NSGRYSLKATNGSGQATSTAELLVKAETAPP 104



 Score = 35.8 bits (81), Expect = 0.24
 Identities = 23/89 (25%), Positives = 34/89 (38%), Gaps = 2/89 (2%)

Query: 561   TVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSG--RIRTESYPDSSTLVIDIAERDD 618
             T   G  +R  + I+  P P   W +  + I  G    +   ES      L I+    DD
Sbjct: 31700 TAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDD 31759

Query: 619   SGVYHINLKNEAGEAHASIKVKVVDFPDP 647
                Y +  +N+ GE     K+ V   P P
Sbjct: 31760 DAEYTVVARNKYGEDSCKAKLTVTLHPPP 31788



 Score = 35.0 bits (79), Expect = 0.41
 Identities = 23/91 (25%), Positives = 37/91 (40%)

Query: 1054 PMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEI 1113
            P F Q L +     G    L   V G P P + + ++   I     +++     + +L I
Sbjct: 104  PNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLI 163

Query: 1114 RKPSPYDGGTYCCKAVNDLGTVEIECKLEVK 1144
             +  P D GTY   A N +G      +L V+
Sbjct: 164  AEAYPEDSGTYSVNATNSVGRATSTAELLVQ 194



 Score = 35.0 bits (79), Expect = 0.41
 Identities = 27/90 (30%), Positives = 39/90 (43%), Gaps = 4/90 (4%)

Query: 1054  PMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEI 1113
             P FT  L +  A+     TL C V  +   K  W K+   IV  P+Y + ++     L+I
Sbjct: 11663 PYFTVKLHDKTAVEKDEITLKCEVSKDVPVK--WFKDGEEIVPSPKYSIKADGLRRILKI 11720

Query: 1114  RKPSPYDGGTYCCKAVND--LGTVEIECKL 1141
             +K    D G Y C    D     V +E +L
Sbjct: 11721 KKADLKDKGEYVCDCGTDKTKANVTVEARL 11750



 Score = 33.9 bits (76), Expect = 0.91
 Identities = 27/119 (22%), Positives = 51/119 (42%), Gaps = 11/119 (9%)

Query: 418  VEGKKHILIIEGATKADAAEYSVM-------TTGGQSSAKLSVDLKPLKILTPLTDQTVN 470
            VE KK + +    T      + V+       T   +  A + + + P  +++ L + TV 
Sbjct: 896  VEVKKEVGVSITGTTVREERFEVLHGREAKVTETARVPAPVEIPVTPPTLVSGLKNVTVI 955

Query: 471  LGKEICLKCEISENIPGK---WTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDY 526
             G+ + L+C IS   P     W +    ++ S   ++  +  I +L+I  A  ED G +
Sbjct: 956  EGESVTLECHIS-GYPSPTVTWYREDYQIESSIDFQITFQSGIARLMIREAFAEDSGRF 1013



 Score = 33.9 bits (76), Expect = 0.91
 Identities = 25/77 (32%), Positives = 40/77 (51%), Gaps = 8/77 (10%)

Query: 3     EPTKKEENEVPA-PAPPPEEPSKEKEAGTTPAKDEEEVSPPSALP---PGLGSRALERK- 57
             EP K E+ + PA P PPP +P +E E  T   K E ++  P+ +P   P +   A E K 
Sbjct: 10965 EPKKLEKVKKPAVPEPPPPKPVEEVEVPTV-TKRERKIPEPTKVPEIKPAIPLPAPEPKP 11023

Query: 58    --DSDWTLVETPPGEEQ 72
               +++   ++ PP E +
Sbjct: 11024 KPEAEVKTIKPPPVEPE 11040



 Score = 33.5 bits (75), Expect = 1.2
 Identities = 35/140 (25%), Positives = 63/140 (45%), Gaps = 11/140 (7%)

Query: 799 KTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIR 858
           + K TI  +         +KA N +G +     +  +LVK    PP     + L+   +R
Sbjct: 62  RAKLTIPAVTKANSGRYSLKATNGSGQATS---TAELLVKAETAPPNF--VQRLQSMTVR 116

Query: 859 RVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTI--IFIRKAERSHSGKY 916
           + G  V L +   G P P + + +DGAEI ++ ++ + S+   +  + I +A    SG Y
Sbjct: 117 Q-GSQVRLQVRVTGIPTPVVKFYRDGAEI-QSSLDFQISQEGDLYSLLIAEAYPEDSGTY 174

Query: 917 DLQV--KVDKFVETASIDIQ 934
            +     V +   TA + +Q
Sbjct: 175 SVNATNSVGRATSTAELLVQ 194



 Score = 33.5 bits (75), Expect = 1.2
 Identities = 43/147 (29%), Positives = 59/147 (40%), Gaps = 10/147 (6%)

Query: 304   PKLEVKWYKNGQE-IRPSTKY-IFEHKGCQRILFINNCQMTDDSEYYVTA----GDEKCS 357
             PK  VKWY+ G+E I    KY I E KG    L I +    D + Y V A    G    +
Sbjct: 30955 PKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQLIIASVTDDDATVYQVRATNQGGSVSGT 31014

Query: 358   TELFVREP-PIMVTKQLED---TTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSR 413
               L V  P  I + K LE      A  GE V ++   S     V  ++ G+++I      
Sbjct: 31015 ASLEVEVPAKIHLPKTLEGMGAVHALRGEVVSIKIPFSGKPDPVITWQKGQDLIDNNGHY 31074

Query: 414   YRIRVEGKKHILIIEGATKADAAEYSV 440
               I       ++   G  + DA  Y V
Sbjct: 31075 QVIVTRSFTSLVFPNGVERKDAGFYVV 31101



 Score = 33.1 bits (74), Expect = 1.6
 Identities = 21/96 (21%), Positives = 41/96 (42%), Gaps = 3/96 (3%)

Query: 854 QTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQ---INIRNSETDTIIFIRKAER 910
           Q+ +   G          G P PE++W +DG  I  +    + I  S+    + I    +
Sbjct: 13  QSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKLTIPAVTK 72

Query: 911 SHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVK 946
           ++SG+Y L+        T++ ++ +     PP  V+
Sbjct: 73  ANSGRYSLKATNGSGQATSTAELLVKAETAPPNFVQ 108



 Score = 33.1 bits (74), Expect = 1.6
 Identities = 19/61 (31%), Positives = 27/61 (44%), Gaps = 1/61 (1%)

Query: 1071 ATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVN 1130
            AT  C     P  K+ W K+ + + +  +YRM S++ V  L I      D   Y C  V 
Sbjct: 2192 ATFECET-SEPFVKVKWYKDGMEVHEGDKYRMHSDRKVHFLSILTIDTSDAEDYSCVLVE 2250

Query: 1131 D 1131
            D
Sbjct: 2251 D 2251



 Score = 33.1 bits (74), Expect = 1.6
 Identities = 55/256 (21%), Positives = 103/256 (40%), Gaps = 21/256 (8%)

Query: 304   PKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTA----GDEKCSTE 359
             P  ++KWY+ G+E+  S KY     G    L +   +  D+  Y   A    G+ + S++
Sbjct: 30560 PLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVGEVETSSK 30619

Query: 360   LFVREPPIMVT--KQLEDTTAYCGERVELE-CEVSEDDANVKWFKNGEEIIPGPKSRYRI 416
             L ++  P         E      G  + L    +      + WF +G++++   ++    
Sbjct: 30620 LLLQATPQFHPGYPLKEKYYGAVGSTLRLHVMYIGRPVPAMTWF-HGQKLLQNSENITIE 30678

Query: 417   RVEGKKHILIIEGATKADAAEYSVMTTG--GQSSAKLSVDL--KPLKILTPLTDQTVNLG 472
               E   H+++     K  A +Y V  +   G   A L V++  KP K   P+  + + L 
Sbjct: 30679 NTEHYTHLVMKNVQRKTHAGKYKVQLSNVFGTVDAILDVEIQDKPDKPTGPIVIEAL-LK 30737

Query: 473   KEICLKCEISENIPGKWTKNGL----PVQESDRLKVVHKG-RIHKLVIANALTEDEGDY- 526
                 +  +   +  G W  N +      +E    ++V     +    I N LTE+ G Y 
Sbjct: 30738 NSAVISWKPPADDGGSWITNYVVEKCEAKEGAEWQLVSSAISVTTCRIVN-LTENAGYYF 30796

Query: 527   -VFAPDAYNVTLPAKV 541
              V A + + ++ P +V
Sbjct: 30797 RVSAQNTFGISDPLEV 30812



 Score = 32.3 bits (72), Expect = 2.7
 Identities = 31/118 (26%), Positives = 46/118 (38%), Gaps = 20/118 (16%)

Query: 1045 YEDFDFS-------EAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDD 1097
            YED + S       E   FT+ + N       +AT  C V  +    +TW K    + + 
Sbjct: 8818 YEDLETSAELRIEAEPIQFTKRIQNIVVSEHQSATFECEVSFDDAI-VTWYKGPTELTES 8876

Query: 1098 PRYRMFSNQGVC-TLEIRKPSPYDGGTYC----------CKAVNDLGTVEIECKLEVK 1144
             +Y  F N G C  + I   +P D G Y            ++  +L     E KLE+K
Sbjct: 8877 QKYN-FRNDGRCHYMTIHNVTPDDEGVYSVIARLEPRGEARSTAELYLTTKEIKLELK 8933



 Score = 32.3 bits (72), Expect = 2.7
 Identities = 16/45 (35%), Positives = 22/45 (48%), Gaps = 3/45 (6%)

Query: 843   PPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEI 887
             PP+  +P + K  Y   VGE V   +     P P +TW K G +I
Sbjct: 31689 PPEFTLPLYNKTAY---VGENVRFGVTITVHPEPHVTWYKSGQKI 31730



 Score = 31.6 bits (70), Expect = 4.5
 Identities = 26/88 (29%), Positives = 33/88 (37%), Gaps = 4/88 (4%)

Query: 1059 PLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSP 1118
            PL +   I G  A L C V       + W  N   I  D R +         L I +   
Sbjct: 2450 PLKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVKGTKQRLVINRTHA 2509

Query: 1119 YDGGTYCCKAVNDLGTVEIECKLEVKVI 1146
             D G Y  K +  +G VE  C L V+ I
Sbjct: 2510 SDEGPY--KLI--VGRVETNCNLSVEKI 2533



 Score = 31.6 bits (70), Expect = 4.5
 Identities = 26/88 (29%), Positives = 35/88 (39%), Gaps = 8/88 (9%)

Query: 3     EPTKKEENEVPAPAPPPEEPSKEKEAGTTPAKDEEEVSPPSALPPGLGSRALERKDSDWT 62
             E    E  E P    P EE + E+E     A++EE   PP A+P        E+K     
Sbjct: 10797 ESPPPEVYEEPEEIAPEEEIAPEEEKPVPVAEEEEPEVPPPAVPEEPKKIIPEKKVPVIK 10856

Query: 63    LVETPPGEEQAKQNANSQLSILFIEKPQ 90
               E PP +E   +          IEKP+
Sbjct: 10857 KPEAPPPKEPEPEKV--------IEKPK 10876



 Score = 31.2 bits (69), Expect = 5.9
 Identities = 15/66 (22%), Positives = 30/66 (45%), Gaps = 1/66 (1%)

Query: 287   YQVDKGGRVRFVVE-LADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDS 345
             Y +  G  ++  +  +  P+  + W K+G+ ++ +T+   E      +L I      D  
Sbjct: 24321 YSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFG 24380

Query: 346   EYYVTA 351
             +Y VTA
Sbjct: 24381 KYTVTA 24386



 Score = 30.8 bits (68), Expect = 7.7
 Identities = 22/58 (37%), Positives = 28/58 (48%), Gaps = 6/58 (10%)

Query: 1     MPEPTKKEENE--VPAPAPPPEEPSKEKEAGTTPAKDEEEVSPPSALP---PGLGSRA 53
             +PEPTK  E +  +P PAP P +P  E E  T      E    P A P   P +G +A
Sbjct: 11001 IPEPTKVPEIKPAIPLPAPEP-KPKPEAEVKTIKPPPVEPEPTPIAAPVTVPVVGKKA 11057


>gi|110349717 titin isoform novex-2 [Homo sapiens]
          Length = 27118

 Score =  299 bits (766), Expect = 9e-81
 Identities = 218/756 (28%), Positives = 346/756 (45%), Gaps = 52/756 (6%)

Query: 297  FVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKC 356
            F  +L+  K  VKWY+NG+EI+   KY FE  G    L I +C++ D+ EY     D K 
Sbjct: 6537 FSCQLSREKANVKWYRNGREIKEGKKYKFEKDGSIHRLIIKDCRLDDECEYACGVEDRKS 6596

Query: 357  STELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRI 416
               LFV E P+ + +  +D     G  V    E+++D   V+W +N   ++ G K  +++
Sbjct: 6597 RARLFVEEIPVEIIRPPQDILEAPGADVVFLAELNKDKVEVQWLRNNMVVVQGDK--HQM 6654

Query: 417  RVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEIC 476
              EGK H L I      D  EY  +    ++ AKL +   P KI T   D  V++GK + 
Sbjct: 6655 MSEGKIHRLQICDIKPRDQGEYRFIAKDKEARAKLELAAAP-KIKTADQDLVVDVGKPLT 6713

Query: 477  LKC--EISENIPGKWTKNGLPV----------QESDRL---KVVHKGRIHKLVIANALTE 521
            +    +       +W K   P+          Q S R+   K   KGR +K+V+ N   +
Sbjct: 6714 MVVPYDAYPKAEAEWFKENEPLSTKTIDTTAEQTSFRILEAKKGDKGR-YKIVLQNKHGK 6772

Query: 522  DEGDYVFAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPK 581
             EG                + VID P  + +    + T T      L  E P++      
Sbjct: 6773 AEGFI-------------NLKVIDVPGPVRN---LEVTETFDGEVSLAWEEPLTDGGSKI 6816

Query: 582  AMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAG-----EAHAS 636
              +    + I   +  + T+        V  + +     ++ ++ +N  G     E    
Sbjct: 6817 IGYVVERRDIKRKTWVLATDRAESCEFTVTGLQKGGVEYLFRVSARNRVGTGEPVETDNP 6876

Query: 637  IKVKV-VDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLN 695
            ++ +   D P PP+  T+T+V      + WEPP YDGG+ I  Y IE + K S RW    
Sbjct: 6877 VEARSKYDVPGPPLNVTITDVNRFGVSLTWEPPEYDGGAEITNYVIELRDKTSIRWDTAM 6936

Query: 696  FDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFV----PLAVTSPPTLLTV 751
                ++ +     ++EG  Y  R+ A N IG+ KPS  + PFV    P+   SPP  LT 
Sbjct: 6937 TVRAEDLSATVTDVVEGQEYSFRVRAQNRIGVGKPSAAT-PFVKVADPIERPSPPVNLTS 6995

Query: 752  DSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDA 811
               T ++V ++W PP   G + + GY++E C EG ++WI  N  L+ +  + +TGL    
Sbjct: 6996 SDQTQSSVQLKWEPPLKDGGSPILGYIIERCEEGKDNWIRCNMKLVPELTYKVTGLEKGN 7055

Query: 812  KIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQ 871
            K   RV A N AG S+P     P+   +    P + +    K      V   + +++P  
Sbjct: 7056 KYLYRVSAENKAGVSDPSEILGPLTADDAFVEPTMDLSA-FKDGLEVIVPNPITILVPST 7114

Query: 872  GKPRPELTWKKDGAEIDK-NQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETAS 930
            G PRP  TW      ++  +++ ++       + I  +ERS  G Y L  K++  V+T S
Sbjct: 7115 GYPRPTATWCFGDKVLETGDRVKMKTLSAYAELVISPSERSDKGIYTL--KLENRVKTIS 7172

Query: 931  --IDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTV 988
              ID+ +I RP  P+ +K  D+  ++V LTW PP DDG + +TGY ++K +     W  V
Sbjct: 7173 GEIDVNVIARPSAPKELKFGDITKDSVHLTWEPPDDDGGSPLTGYVVEKREVSRKTWTKV 7232

Query: 989  IEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDA 1024
            ++       T+ +LV G EY F+V + N CG  E A
Sbjct: 7233 MDFVTDLEFTVPDLVQGKEYLFKVCARNKCGPGEPA 7268



 Score =  288 bits (737), Expect = 2e-77
 Identities = 165/503 (32%), Positives = 269/503 (53%), Gaps = 17/503 (3%)

Query: 536   TLPAKVHV---IDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIM 592
             TLP  V     I+PP+I LD  D    V + A   LRL + I G P P+  W + +  + 
Sbjct: 18786 TLPGSVVAQERIEPPEIELDA-DLRKVVVLRASATLRLFVTIKGRPEPEVKWEKAEGILT 18844

Query: 593   EGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPT 652
             +   R + E     + LVID   R DSG Y++ L+N +G   A + V+V+D P  PV  T
Sbjct: 18845 D---RAQIEVTSSFTMLVIDNVTRFDSGRYNLTLENNSGSKTAFVNVRVLDSPSAPVNLT 18901

Query: 653   VTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEG 712
             + EV  D   ++WEPP  DGG+ I  Y +E+++     +  +  + C +TTF  + + EG
Sbjct: 18902 IREVKKDSVTLSWEPPLIDGGAKITNYIVEKRETTRKAYATITNN-CTKTTFRIENLQEG 18960

Query: 713   VAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAA 772
              +Y  R+ A N  GI  P+  + P        PP  +T+  VT  T T++W  P+  G +
Sbjct: 18961 CSYYFRVLASNEYGIGLPAETTEPVKVSEPPLPPGRVTLVDVTRNTATIKWEKPESDGGS 19020

Query: 773   GLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYS 832
              + GYV+E   +G+E W    +  +   + TI+GL    +   RV AVN  G S+P+   
Sbjct: 19021 KITGYVVEMQTKGSEKWSTCTQ--VKTLEATISGLTAGEEYVFRVAAVNEKGRSDPRQLG 19078

Query: 833   QPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEI-DKNQ 891
              P++ ++I   P + +P H   T+  +  E + + +PF+G+P+  + W+KDG  + +  +
Sbjct: 19079 VPVIARDIEIKPSVELPFH---TFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTR 19135

Query: 892   INIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVW 951
             +N+ +S+T T + I++A +   G Y+L V       T  I I ++DRPGPP  ++I++V 
Sbjct: 19136 VNVSSSKTVTSLSIKEASKEDVGTYELCVSNSAGSITVPITIIVLDRPGPPGPIRIDEVS 19195

Query: 952   GENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFR 1011
              +++ ++W PP+ DG   I+ Y ++K +  S  W  V +   RTS  I  L  G+EY FR
Sbjct: 19196 CDSITISWNPPEYDGGCQISNYIVEKKETTSTTWHIVSQAVARTSIKIVRLTTGSEYQFR 19255

Query: 1012  VFSENMCGLSEDATMTKESAVIA 1034
             V +EN  G S   + ++ SAV+A
Sbjct: 19256 VCAENRYGKS---SYSESSAVVA 19275



 Score =  276 bits (707), Expect = 6e-74
 Identities = 176/570 (30%), Positives = 286/570 (50%), Gaps = 35/570 (6%)

Query: 463   PLTDQTVNLGKEICLKCEISENIPGKWTKNGLPVQ------ESDRLKVVHKGRIHKLVIA 516
             P+ D    +   I  KC++S    G+WT    P        E ++L   H+       I 
Sbjct: 16556 PIYDGGCEIQGYIVEKCDVSV---GEWTMCTPPTGINKTNIEVEKLLEKHEYNFRICAIN 16612

Query: 517   NALTEDEGDYVFAPDAYNVTLPAKVHV---IDPPKIILDGLDADNTVTVIAGNKLRLEIP 573
              A   +  D           +P  + V   ++ P I LD L+    + + AG  LRL +P
Sbjct: 16613 KAGVGEHAD-----------VPGPIIVEEKLEAPDIDLD-LELRKIINIRAGGSLRLFVP 16660

Query: 574   ISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEA 633
             I G P P+  W + D  I + +    T S+   ++LV+D   R DSG Y + L+N +G  
Sbjct: 16661 IKGRPTPEVKWGKVDGEIRDAAIIDVTSSF---TSLVLDNVNRYDSGKYTLTLENSSGTK 16717

Query: 634   HASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMR 693
              A + V+V+D P PPV   VTE+  D   + WEPP  DGGS I  Y +E+++     +  
Sbjct: 16718 SAFVTVRVLDTPSPPVNLKVTEITKDSVSITWEPPLLDGGSKIKNYIVEKREATRKSYAA 16777

Query: 694   LNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDS 753
             +  + C + +++  ++ EG +Y  R+ A N  GI  P+  + P     V  PP  +TVD 
Sbjct: 16778 VVTN-CHKNSWKIDQLQEGCSYYFRVTAENEYGIGLPAQTADPIKVAEVPQPPGKITVDD 16836

Query: 754   VTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKI 813
             VT  +V++ W  P+H G + +  Y++E   + +E W    +  +   +  IT L    + 
Sbjct: 16837 VTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKHSEKWSECAR--VKSLQAVITNLTQGEEY 16894

Query: 814   FVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGK 873
               RV AVN  G S+P+  + PI+ K+++  P +   +    +Y  +VG+ + + +P  G+
Sbjct: 16895 LFRVVAVNEKGRSDPRSLAVPIVAKDLVIEPDV---KPAFSSYSVQVGQDLKIEVPISGR 16951

Query: 874   PRPELTWKKDGAEIDK-NQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASID 932
             P+P +TW KDG  + +  +IN+ +S   T + I++  +   G+Y + V      +TASI+
Sbjct: 16952 PKPTITWTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQYGITVANVVGQKTASIE 17011

Query: 933   IQIIDRPGPPQ-IVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEH 991
             I  +D+P PP+  VK +DV  E++ L+W PP   G   IT Y +QK D  +  W  V   
Sbjct: 17012 IVTLDKPDPPKGPVKFDDVSAESITLSWNPPLYTGGCQITNYIVQKRDTTTTVWDVVSAT 17071

Query: 992   YHRTSATITELVIGNEYYFRVFSENMCGLS 1021
               RT+  +T+L  G EY FR+F+EN  G S
Sbjct: 17072 VARTTLKVTKLKTGTEYQFRIFAENRYGQS 17101



 Score =  272 bits (695), Expect = 2e-72
 Identities = 159/562 (28%), Positives = 280/562 (49%), Gaps = 19/562 (3%)

Query: 544   IDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESY 603
             ++ P++ LD  +    + V AG   R+ IP  G P P+  WSR +    E + +++ E  
Sbjct: 17714 LEAPELDLDS-ELRKGIVVRAGGSARIHIPFKGRPTPEITWSREEG---EFTDKVQIEKG 17769

Query: 604   PDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIM 663
              + + L ID  +R+D+G Y + L+N +G   A + VKV+D P PP    V EV  D   +
Sbjct: 17770 VNYTQLSIDNCDRNDAGKYILKLENSSGSKSAFVTVKVLDTPGPPQNLAVKEVRKDSAFL 17829

Query: 664   NWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVN 723
              WEPP  DGG+ +  Y I++++     +  ++   C +T+F+ + + EG  Y  R+ A N
Sbjct: 17830 VWEPPIIDGGAKVKNYVIDKRESTRKAYANVS-SKCSKTSFKVENLTEGAIYYFRVMAEN 17888

Query: 724   AIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCF 783
               G+  P             SPP  +T+  V+ T+ ++ W  P+H G + + GYV+E   
Sbjct: 17889 EFGVGVPVETVDAVKAAEPPSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVEMQP 17948

Query: 784   EGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEP 843
             +GTE W +  +  +      +TGL +  +   RVKA N  G S+P+    P++ K++   
Sbjct: 17949 KGTEKWSIVAESKV--CNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQ 18006

Query: 844   PKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDK-NQINIRNSETDTI 902
             P +++P +   TY  + GE + + IP  G+PRP ++W KDG  + +  ++N+  + T T+
Sbjct: 18007 PSLKLPFN---TYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTV 18063

Query: 903   IFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPP-QIVKIEDVWGENVALTWTP 961
             + I++  +   GKY +         T ++ + ++++PGPP   V+ ++V  + V ++W P
Sbjct: 18064 LHIKEGNKDDFGKYTVTATNSAGTATENLSVIVLEKPGPPVGPVRFDEVSADFVVISWEP 18123

Query: 962   PKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLS 1021
             P   G   I+ Y ++K D  +  W  V     RT+  IT+L  G EY FR+F+EN  G S
Sbjct: 18124 PAYTGGCQISNYIVEKRDTTTTTWHMVSATVARTTIKITKLKTGTEYQFRIFAENRYGKS 18183

Query: 1022  EDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNAT--LNCSVRG 1079
               A +  ++ ++      +K P      F  +    Q LV  +       T  +   +  
Sbjct: 18184 --APLDSKAVIVQYP---FKEPGPPGTPFVTSISKDQMLVQWHEPVNDGGTKIIGYHLEQ 18238

Query: 1080  NPKPKITWMKNKVAIVDDPRYR 1101
               K  I W+K     + D +++
Sbjct: 18239 KEKNSILWVKLNKTPIQDTKFK 18260



 Score =  258 bits (658), Expect = 3e-68
 Identities = 148/478 (30%), Positives = 252/478 (52%), Gaps = 12/478 (2%)

Query: 546   PPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPD 605
             PP+I LD  D    VT+ A   LRL +PI G P P+  W+R     ++ +    T SY  
Sbjct: 15552 PPEIELDA-DLRKVVTIRACCTLRLFVPIKGRPAPEVKWARDHGESLDKASIESTSSY-- 15608

Query: 606   SSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNW 665
              + L++    R DSG Y + ++N +G   A + V+V+D P PP    V EV      + W
Sbjct: 15609 -TLLIVGNVNRFDSGKYILTVENSSGSKSAFVNVRVLDTPGPPQDLKVKEVTKTSVTLTW 15667

Query: 666   EPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAI 725
             +PP  DGGS I  Y +E+++     +  +  + C +T+++  ++ EG +Y  R+ A N  
Sbjct: 15668 DPPLLDGGSKIKNYIVEKRESTRKAYSTVATN-CHKTSWKVDQLQEGCSYYFRVLAENEY 15726

Query: 726   GISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEG 785
             GI  P+  +          PP  +T+  VT  +V++ W  P+H G + + GY++E   +G
Sbjct: 15727 GIGLPAETAESVKASERPLPPGKITLMDVTRNSVSLSWEKPEHDGGSRILGYIVEMQTKG 15786

Query: 786   TEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPK 845
             ++ W  A    +  T+ TITGL    +   RV A N  G S+P+  S P++ K+++ PP 
Sbjct: 15787 SDKW--ATCATVKVTEATITGLIQGEEYSFRVSAQNEKGISDPRQLSVPVIAKDLVIPPA 15844

Query: 846   IRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDK-NQINIRNSETDTIIF 904
              ++   L  T+    GE + + +PF G+P P +TW KD   + +  ++N  ++E ++++ 
Sbjct: 15845 FKL---LFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAESTENNSLLT 15901

Query: 905   IRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQ-IVKIEDVWGENVALTWTPPK 963
             I+ A R   G Y +++         ++++ ++D+PGPP   VK+++V  +++ L+W PPK
Sbjct: 15902 IKDACREDVGHYVVKLTNSAGEAIETLNVIVLDKPGPPTGPVKMDEVTADSITLSWGPPK 15961

Query: 964   DDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLS 1021
              DG ++I  Y ++K D  +  W  V     RT+     L  G EY FR+ +EN  G S
Sbjct: 15962 YDGGSSINNYIVEKRDTSTTTWQIVSATVARTTIKACRLKTGCEYQFRIAAENRYGKS 16019



 Score =  255 bits (651), Expect = 2e-67
 Identities = 157/482 (32%), Positives = 251/482 (52%), Gaps = 13/482 (2%)

Query: 547   PKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDS 606
             P + LD    D  V V AG  +R+   +SG+PPP   W+  ++ + + +     E+   S
Sbjct: 10217 PDLQLDASVRDRIV-VHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEA---TIETTAIS 10272

Query: 607   STLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTE-VGDDWCIMNW 665
             S++VI   +R   GVY +  KNEAGE   +I V V+D P P   P +   + ++ C + W
Sbjct: 10273 SSMVIKNCQRSHQGVYSLLAKNEAGERKKTIIVDVLDVPGPVGTPFLAHNLTNESCKLTW 10332

Query: 666   EPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAI 725
               P  DGGSPI  Y IE+++     W  + + + ++     + +I+G AY  RI A N+I
Sbjct: 10333 FSPEDDGGSPITNYVIEKRESDRRAWTPVTYTVTRQNA-TVQGLIQGKAYFFRIAAENSI 10391

Query: 726   GISKPSMPSRPFV---PLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYC 782
             G+      S   V   P+ V   P  L V  VT  TVT+ W PP + G + +  YVLE  
Sbjct: 10392 GMGPFVETSEALVIREPITVPERPEDLEVKEVTKNTVTLTWNPPKYDGGSEIINYVLESR 10451

Query: 783   FEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIE 842
               GTE +     D +   K+T+ GL        RV AVN  G  +P + ++PI  K+ + 
Sbjct: 10452 LIGTEKFHKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGKPSFCTKPITCKDELA 10511

Query: 843   PPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEI-DKNQINIRNSETDT 901
             PP + +    K T   RVGEA  L   + GKP+P+++W KD A++ + ++ +I+ +    
Sbjct: 10512 PPTLHLDFRDKLTI--RVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATL 10569

Query: 902   IIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPP-QIVKIEDVWGENVALTWT 960
              +   KA+RS SGKY + V+           + ++DRPGPP   V  ++V  + + ++W 
Sbjct: 10570 ALEKIKAKRSDSGKYCVVVENSTGSRKGFCQVNVVDRPGPPVGPVSFDEVTKDYMVISWK 10629

Query: 961   PPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGL 1020
             PP DDG + IT Y I+K +     W  V     +T+  +++L+ G +Y FR+ +EN+ G+
Sbjct: 10630 PPLDDGGSKITNYIIEKKEVGKDVWMPVTSASAKTTCKVSKLLEGKDYIFRIHAENLYGI 10689

Query: 1021  SE 1022
             S+
Sbjct: 10690 SD 10691



 Score =  255 bits (651), Expect = 2e-67
 Identities = 143/470 (30%), Positives = 242/470 (51%), Gaps = 16/470 (3%)

Query: 559   TVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSS----TLVIDIA 614
             T+ V AG    + +P  G P P  +WS+ D  +       RT +Y D++    +L I+ A
Sbjct: 19890 TLIVKAGASFTMTVPFRGRPVPNVLWSKPDTDL-------RTRAYVDTTDSRTSLTIENA 19942

Query: 615   ERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGS 674
              R+DSG Y + ++N    A  ++ VKV+D P PP   TV +V  +  +++W+ P  DGG+
Sbjct: 19943 NRNDSGKYTLTIQNVLSAASLTLVVKVLDTPGPPTNITVQDVTKESAVLSWDVPENDGGA 20002

Query: 675   PILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPS 734
             P+  Y IE+++     W+ +  + C   +++   + EG  Y  R+   N  G+  P+   
Sbjct: 20003 PVKNYHIEKREASKKAWVSVT-NNCNRLSYKVTNLQEGAIYYFRVSGENEFGVGIPAETK 20061

Query: 735   RPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANK 794
                      SPP  L V S++  +V++ W  P+H G + +  YV+E   +G ++W+    
Sbjct: 20062 EGVKITEKPSPPEKLGVTSISKDSVSLTWLKPEHDGGSRIVHYVVEALEKGQKNWVKC-- 20119

Query: 795   DLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQ 854
              +   T   ++GL  +++ F RV A N AG S+P+    P+L+KE +EPP+I +      
Sbjct: 20120 AVAKSTHHVVSGLRENSEYFFRVFAENQAGLSDPRELLLPVLIKEQLEPPEIDMKNFPSH 20179

Query: 855   TYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKN-QINIRNSETDTIIFIRKAERSHS 913
             T   R G  + + IP  GKP P++T  +DG  +    + N   +  +  I ++++  + +
Sbjct: 20180 TVYVRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADA 20239

Query: 914   GKYDLQVKVDKFVETASIDIQIIDRPGPPQ-IVKIEDVWGENVALTWTPPKDDGNAAITG 972
             G+Y++          A I+I ++DRPGPP   V I D+  E+V L W PPK DG + +T 
Sbjct: 20240 GRYEITAANSSGTTKAFINIVVLDRPGPPTGPVVISDITEESVTLKWEPPKYDGGSQVTN 20299

Query: 973   YTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSE 1022
             Y + K +  +  W  V     RT   + +L  G EY FR+ +EN  G+S+
Sbjct: 20300 YILLKRETSTAVWTEVSATVARTMMKVMKLTTGEEYQFRIKAENRFGISD 20349



 Score =  252 bits (644), Expect = 1e-66
 Identities = 152/470 (32%), Positives = 240/470 (51%), Gaps = 10/470 (2%)

Query: 555   DADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIA 614
             D   TVT+ AG  LRL + +SG PPP   WS+    +   +    TESY   S L++D  
Sbjct: 23146 DLKKTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAIIDTTESY---SLLIVDKV 23202

Query: 615   ERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGS 674
              R D+G Y I  +N++G+  A++ VKV D P P  +  V EV  D   + WE P  DGG+
Sbjct: 23203 NRYDAGKYTIEAENQSGKKSATVLVKVYDTPGPCPSVKVKEVSRDSVTITWEIPTIDGGA 23262

Query: 675   PILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPS 734
             P+  Y +E K++ + R  +     C +T +    ++EG  Y  R+   N  GI +P   S
Sbjct: 23263 PVNNYIVE-KREAAMRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYGIGEPCETS 23321

Query: 735   RPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDW--IVA 792
                +   V   P  L V  VT +TVT+ W  P + G + L GYVLE C  GTE W  +V 
Sbjct: 23322 DAVLVSEVPLVPAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGTERWMKVVT 23381

Query: 793   NKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHL 852
              K  +   + T+T L    +   R++A N  G SEP+     + V+++   P I +    
Sbjct: 23382 LKPTV--LEHTVTSLNEGEQYLFRIRAQNEKGVSEPRETVTAVTVQDLRVLPTIDLSTMP 23439

Query: 853   KQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEI-DKNQINIRNSETDTIIFIRKAERS 911
             ++T     G  V LVIP  G+P P  +W   G+++ +  ++ +        + IR+    
Sbjct: 23440 QKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAKLTIRETTIR 23499

Query: 912   HSGKYDLQVKVDKFVETASIDIQIIDRPGPPQ-IVKIEDVWGENVALTWTPPKDDGNAAI 970
              +G+Y L++K      + +I + I+D+PGPP   +KI+++   ++ ++W PP+ DG A +
Sbjct: 23500 DTGEYTLELKNVTGTTSETIKVIILDKPGPPTGPIKIDEIDATSITISWEPPELDGGAPL 23559

Query: 971   TGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGL 1020
             +GY +++ D     W  V E   R++   T L  GNEY FRV + N  G+
Sbjct: 23560 SGYVVEQRDAHRPGWLPVSESVTRSTFKFTRLTEGNEYVFRVAATNRFGI 23609



 Score =  249 bits (636), Expect = 1e-65
 Identities = 151/508 (29%), Positives = 245/508 (48%), Gaps = 22/508 (4%)

Query: 533  YNVTLPAKVHVIDPPKIILDGLDADNT--------------VTVIAGNKLRLEIPISGEP 578
            Y V+   K  V DP +I L  L AD+               + VI  N + + +P +G P
Sbjct: 7059 YRVSAENKAGVSDPSEI-LGPLTADDAFVEPTMDLSAFKDGLEVIVPNPITILVPSTGYP 7117

Query: 579  PPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIK 638
             P A W  GDK ++E   R++ ++    + LVI  +ER D G+Y + L+N        I 
Sbjct: 7118 RPTATWCFGDK-VLETGDRVKMKTLSAYAELVISPSERSDKGIYTLKLENRVKTISGEID 7176

Query: 639  VKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDL 698
            V V+  P  P      ++  D   + WEPP  DGGSP+ GY +E+++     W ++  D 
Sbjct: 7177 VNVIARPSAPKELKFGDITKDSVHLTWEPPDDDGGSPLTGYVVEKREVSRKTWTKV-MDF 7235

Query: 699  CKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPF---VPLAVTSPPTLLTVDSVT 755
              +  F    +++G  Y  ++ A N  G  +P+    P     P  V  PP  +     T
Sbjct: 7236 VTDLEFTVPDLVQGKEYLFKVCARNKCGPGEPAYVDEPVNMSTPATVPDPPENVKWRDRT 7295

Query: 756  DTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFV 815
              ++ + W PP + G + + GY++E C  G++ W+   +  + +TK  +TGL        
Sbjct: 7296 ANSIFLTWDPPKNDGGSRIKGYIVERCPRGSDKWVACGEP-VAETKMEVTGLEEGKWYAY 7354

Query: 816  RVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPR 875
            RVKA+N  GAS+P   ++ I   +  E P+I +   L      + G  + L     GKP 
Sbjct: 7355 RVKALNRQGASKPSRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPE 7414

Query: 876  PELTWKKDGAEIDKN-QINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQ 934
            P++TW K    + ++ +I I N    + + I  ++RS +G Y ++        TA +++ 
Sbjct: 7415 PKITWTKADMILKQDKRITIENVPKKSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVN 7474

Query: 935  IIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHR 994
            ++D+PGPP    I DV  E+  LTW PP+DDG + IT Y +++    S  W  +      
Sbjct: 7475 VLDKPGPPAAFDITDVTNESCLLTWNPPRDDGGSKITNYVVERRATDSEVWHKLSSTVKD 7534

Query: 995  TSATITELVIGNEYYFRVFSENMCGLSE 1022
            T+   T+L+   EY FRV +ENM G+ E
Sbjct: 7535 TNFKATKLIPNKEYIFRVAAENMYGVGE 7562



 Score =  247 bits (631), Expect = 4e-65
 Identities = 170/584 (29%), Positives = 278/584 (47%), Gaps = 33/584 (5%)

Query: 461   LTPLTDQTVNL--GKEICLKCEISENIP--GKWTKNGLPVQESDRLKVVHKGRIHKLVIA 516
             L+ +  +T+++  G+ + L   I+   P    W   G  ++ES+R+ V    ++ KL I 
Sbjct: 23435 LSTMPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAKLTIR 23494

Query: 517   NALTEDEGDYVFAPDAYNVTLPA----KVHVIDPP-----KIILDGLDADNTVTVIAGNK 567
                  D G+Y    +  NVT       KV ++D P      I +D +DA +        +
Sbjct: 23495 ETTIRDTGEYTL--ELKNVTGTTSETIKVIILDKPGPPTGPIKIDEIDATSITISWEPPE 23552

Query: 568   LRLEIPISG-----EPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVY 622
             L    P+SG         +  W    +++   + +    +  +     +    R   G Y
Sbjct: 23553 LDGGAPLSGYVVEQRDAHRPGWLPVSESVTRSTFKFTRLTEGNEYVFRVAATNRFGIGSY 23612

Query: 623   HINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIE 682
                L++E  E  +SI++     P PP    + +V  D   + W PP  DGGS + GY +E
Sbjct: 23613 ---LQSEVIECRSSIRI-----PGPPETLQIFDVSRDGMTLTWYPPEDDGGSQVTGYIVE 23664

Query: 683   RKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAV 742
             RK+ ++ RW+R+N      T +    + EG+ YE R+ A+NA G  KPS PS+P V +  
Sbjct: 23665 RKEVRADRWVRVNKVPVTMTRYRSTGLTEGLEYEHRVTAINARGSGKPSRPSKPIVAMDP 23724

Query: 743   TSPPTLLTVDSVTDTT---VTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDK 799
              +PP       VTDTT   V++ W  P+  G + + GY++E       +W   N      
Sbjct: 23725 IAPPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTKCNTTPTKI 23784

Query: 800   TKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRR 859
              ++T+T LP  A+   RV A NA G  EP      + V E++E P   +    ++    R
Sbjct: 23785 REYTLTHLPQGAEYRFRVLACNAGGPGEPAEVPGTVKVTEMLEYPDYELDERYQEGIFVR 23844

Query: 860   VGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQ 919
              G  + L IP +GKP P   W K+G +I K  + I  SET T + I++A+R  SG YDL 
Sbjct: 23845 QGGVIRLTIPIKGKPFPICKWTKEGQDISKRAM-IATSETHTELVIKEADRGDSGTYDLV 23903

Query: 920   VKVDKFVETASIDIQIIDRPGPPQ-IVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKA 978
             ++     +   I +++I  P  P+  ++ +D+   +V ++W PP DDG A I GY +++ 
Sbjct: 23904 LENKCGKKAVYIKVRVIGSPNSPEGPLEYDDIQVRSVRVSWRPPADDGGADILGYILERR 23963

Query: 979   DKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSE 1022
             +     W+T+      TS  +  L    EY+FRV +EN  G+S+
Sbjct: 23964 EVPKAAWYTIDSRVRGTSLVVKGLKENVEYHFRVSAENQFGISK 24007



 Score =  245 bits (626), Expect = 2e-64
 Identities = 153/493 (31%), Positives = 238/493 (48%), Gaps = 17/493 (3%)

Query: 543   VIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRG--DKAIMEGSGRIRT 600
             +++PP+I LD       V V AG  +RL   + G P PK  W +   D  + +G    + 
Sbjct: 12295 ILEPPEIDLDA-SMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVVRKG----QV 12349

Query: 601   ESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDW 660
             +     + LVI  + RDDSG Y + L N AGE    + V+V+D P P     V++V    
Sbjct: 12350 DLVDTMAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFVNVRVLDTPGPVSDLKVSDVTKTS 12409

Query: 661   CIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIF 720
             C ++W PP  DGGS +  Y +E+++     W  +  ++ K+T+F    ++ G  Y  R+ 
Sbjct: 12410 CHVSWAPPENDGGSQVTHYIVEKREADRKTWSTVTPEV-KKTSFHVTNLVPGNEYYFRVT 12468

Query: 721   AVNAIGISKPSMPSRPFV---PLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGY 777
             AVN  G   P+   +P +   PL+   PP  L V  +T  + T+ W PP   G A +DGY
Sbjct: 12469 AVNEYGPGVPTDVPKPVLASDPLSEPDPPRKLEVTEMTKNSATLAWLPPLRDGGAKIDGY 12528

Query: 778   VLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILV 837
             +  Y  E           ++      +TGL    K   RV A NA G S P+        
Sbjct: 12529 ITSYREEEQPADRWTEYSVVKDLSLVVTGLKEGKKYKFRVAARNAVGVSLPREAEGVYEA 12588

Query: 838   KEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAE-IDKNQINIRN 896
             KE + PPKI +P  +      + G+ + +     GKP P   WKK   E +  + + +  
Sbjct: 12589 KEQLLPPKILMPEQI----TIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHK 12644

Query: 897   SETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQ-IVKIEDVWGENV 955
             +++ +I+ I+   R  SG Y L  +     +T  I + ++D PGPPQ    I D+  +  
Sbjct: 12645 ADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPGPPQPPFDISDIDADAC 12704

Query: 956   ALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSE 1015
             +L+W  P +DG + IT Y ++K D    +W T +    +TS  + +L+ G EY FRV +E
Sbjct: 12705 SLSWHIPLEDGGSNITNYIVEKCDVSRGDWVTALASVTKTSCRVGKLIPGQEYIFRVRAE 12764

Query: 1016  NMCGLSEDATMTK 1028
             N  G+SE  T  K
Sbjct: 12765 NRFGISEPLTSPK 12777



 Score =  243 bits (621), Expect = 6e-64
 Identities = 152/515 (29%), Positives = 259/515 (50%), Gaps = 25/515 (4%)

Query: 543   VIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTES 602
             ++ PP+  LD  D   T+ + AG  +RL +P+ G PPPK  WS+ +  + +  G +  +S
Sbjct: 13382 ILIPPEGELDA-DLRKTLILRAGVTMRLYVPVKGRPPPKITWSKPNVNLRDRIG-LDIKS 13439

Query: 603   YPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCI 662
                 + L  +   + D+G Y + L+N  G+   +I VKV+D P PPV  TV E+  D   
Sbjct: 13440 TDFDTFLRCENVNKYDAGKYILTLENSCGKKEYTIVVKVLDTPGPPVNVTVKEISKDSAY 13499

Query: 663   MNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAV 722
             + WEPP  DGGSPI+ Y ++++  +   W  +  + C +T+F    + EG +Y  R+FA 
Sbjct: 13500 VTWEPPIIDGGSPIINYVVQKRDAERKSWSTVTTE-CSKTSFRVANLEEGKSYFFRVFAE 13558

Query: 723   NAIGISKPSMPSRPFVPLAVTSPPTL-LTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEY 781
             N  GI  P   +R  V  + T  P + L V SV+ ++ ++ W+ P   G + + GYV+++
Sbjct: 13559 NEYGIGDPG-ETRDAVKASQTPGPVVDLKVRSVSKSSCSIGWKKPHSDGGSRIIGYVVDF 13617

Query: 782   CFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEII 841
               E  + W    K L    +++   L    +   RV A N  G   P   +  ++ ++ +
Sbjct: 13618 LTEENK-WQRVMKSL--SLQYSAKDLTEGKEYTFRVSAENENGEGTPSEIT--VVARDDV 13672

Query: 842   EPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKK-DGAEIDKNQINIRNSETD 900
               P + +       Y+ +      L IP +GKP P ++WKK +       ++++ +S  +
Sbjct: 13673 VAPDLDLKGLPDLCYLAKENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVESSAVN 13732

Query: 901   TIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPG-PPQIVKIEDVWGENVALTW 959
             T + +   ++S +GKY + +K     +  +I I+++ +PG P   +K ++V  E + L W
Sbjct: 13733 TTLIVYDCQKSDAGKYTITLKNVAGTKEGTISIKVVGKPGIPTGPIKFDEVTAEAMTLKW 13792

Query: 960   TPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCG 1019
              PPKDDG + IT Y ++K D  + +W T      +T+  +T L  G EY FRV +EN  G
Sbjct: 13793 APPKDDGGSEITNYILEKRDSVNNKWVTCASAVQKTTFRVTRLHEGMEYTFRVSAENKYG 13852

Query: 1020  LSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAP 1054
             + E     K   ++AR            FD  +AP
Sbjct: 13853 VGEG---LKSEPIVAR----------HPFDVPDAP 13874



 Score =  243 bits (620), Expect = 8e-64
 Identities = 202/709 (28%), Positives = 322/709 (45%), Gaps = 69/709 (9%)

Query: 357   STELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKW----FKNGEEIIP---- 408
             S  L +REP I V ++ ED        +E++ EV+++   + W    +  G EII     
Sbjct: 10400 SEALVIREP-ITVPERPED--------LEVK-EVTKNTVTLTWNPPKYDGGSEIINYVLE 10449

Query: 409   ----GPKSRYRIRVEGK-KHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTP 463
                 G +  +++  +        ++G  + D  EY V         K S   KP+     
Sbjct: 10450 SRLIGTEKFHKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGKPSFCTKPITCKDE 10509

Query: 464   LTDQTVNLGKEICLKCEISE------NIPGK------WTKNGLPVQESDRLKVVHKGRIH 511
             L   T++L     L   + E         GK      W K+   V E DR  +       
Sbjct: 10510 LAPPTLHLDFRDKLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATL 10569

Query: 512   KLVIANALTEDEGDYVFAPDAYNVTLPAK----VHVIDPPKIILDGLDADNTVTVIAGNK 567
              L    A   D G Y    +  N T   K    V+V+D P   +  +  D          
Sbjct: 10570 ALEKIKAKRSDSGKYCVVVE--NSTGSRKGFCQVNVVDRPGPPVGPVSFDEVT------- 10620

Query: 568   LRLEIPISGEPPPKAMWSRGDKAIMEGSGRIR------TESYPDSSTLVIDIAERDDSGV 621
              +  + IS +PP     S+    I+E     +      T +   ++  V  + E  D  +
Sbjct: 10621 -KDYMVISWKPPLDDGGSKITNYIIEKKEVGKDVWMPVTSASAKTTCKVSKLLEGKDY-I 10678

Query: 622   YHINLKNEAG--EAHASIKVKVVD---FPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPI 676
             + I+ +N  G  +   S  +K  D    PD P  P VTEV  D  ++ W  P +DGG PI
Sbjct: 10679 FRIHAENLYGISDPLVSDSMKAKDRFRVPDAPDQPIVTEVTKDSALVTWNKP-HDGGKPI 10737

Query: 677   LGYFIERKKKQSSRWMRLNFD-LCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSR 735
               Y +E+++  S RW R+  D +   T F    ++EG  YE R+ A N IGI  PS PS+
Sbjct: 10738 TNYILEKRETMSKRWARVTKDPIHPYTKFRVPDLLEGCQYEFRVSAENEIGIGDPSPPSK 10797

Query: 736   PFV---PLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVA 792
             P     P+A  SPP        T  +V + W+PP H G + + GY++EY   G E+W  A
Sbjct: 10798 PVFAKDPIAKPSPPVNPEAIDTTCNSVDLTWQPPRHDGGSKILGYIVEYQKVGDEEWRRA 10857

Query: 793   NK--DLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPR 850
             N   +   +TK+ +TGL        RV AVNAAG S+P +  +P+LVK+ +EPP++ +  
Sbjct: 10858 NHTPESCPETKYKVTGLRDGQTYKFRVLAVNAAGESDPAHVPEPVLVKDRLEPPELILDA 10917

Query: 851   HLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAER 910
             ++ +    +VG+ + L    +G P P++TWKK+  +    +  I  +   + + IR A  
Sbjct: 10918 NMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAP-TKARIDVTPVGSKLEIRNAAH 10976

Query: 911   SHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAI 970
                G Y L V+     +T S+ + ++D+PGPP+ +++ ++  ++  LTW  P DDG + I
Sbjct: 10977 EDGGIYSLTVENPAGSKTVSVKVLVLDKPGPPRDLEVSEIRKDSCYLTWKEPLDDGGSVI 11036

Query: 971   TGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCG 1019
             T Y +++ D  S +W  +     + S     L  GN+Y FRV +EN  G
Sbjct: 11037 TNYVVERRDVASAQWSPLSATSKKKSHFAKHLNEGNQYLFRVAAENQYG 11085



 Score =  243 bits (620), Expect = 8e-64
 Identities = 166/560 (29%), Positives = 272/560 (48%), Gaps = 26/560 (4%)

Query: 489   WTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAKVH--VIDP 546
             W K+G+ ++E  R +++       L + + +  D G YV        T    V+  V+D 
Sbjct: 19518 WAKDGIEIEERARTEIISTDNHTLLTVKDCIRRDTGQYVLTLKNVAGTRSVAVNCKVLDK 19577

Query: 547   P-----KIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTE 601
             P      + ++GL A+         +      I      K   S     I EG  ++   
Sbjct: 19578 PGPPAGPLEINGLTAEKCSLSWGRPQEDGGADIDYYIVEKRETSHLAWTICEGELQM--- 19634

Query: 602   SYPDSSTLVIDIAERDDSGVYHINLKNE--AGEAHASIKVKVVD---FPDPPVAPTVTEV 656
                 +S  V  + + ++  ++ +   N+   GE   S+ +K +D    P PP +  +T V
Sbjct: 19635 ----TSCKVTKLLKGNEY-IFRVTGVNKYGVGEPLESVAIKALDPFTVPSPPTSLEITSV 19689

Query: 657   GDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYE 716
               +   + W  P  DGGS I GY IER++K S RW+R+N     +   +   + EG  YE
Sbjct: 19690 TKESMTLCWSRPESDGGSEISGYIIERREKNSLRWVRVNKKPVYDLRVKSTGLREGCEYE 19749

Query: 717   VRIFAVNAIGISKPSMPS---RPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAG 773
              R++A NA G+S PS  S   R   P+ + SPP+   +     TT+T+ W  P   G A 
Sbjct: 19750 YRVYAENAAGLSLPSETSPLIRAEDPVFLPSPPSKPKIVDSGKTTITIAWVKPLFDGGAP 19809

Query: 774   LDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQ 833
             + GY +EY      DW  + + L   T++TI+GL T A+   RVK+VN  GAS+P   S 
Sbjct: 19810 ITGYTVEYKKSDDTDWKTSIQSLRG-TEYTISGLTTGAEYVFRVKSVNKVGASDPSDSSD 19868

Query: 834   PILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQIN 893
             P + KE  E P   I   +++T I + G +  + +PF+G+P P + W K   ++ + +  
Sbjct: 19869 PQIAKEREEEPLFDIDSEMRKTLIVKAGASFTMTVPFRGRPVPNVLWSKPDTDL-RTRAY 19927

Query: 894   IRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGE 953
             +  +++ T + I  A R+ SGKY L ++      + ++ ++++D PGPP  + ++DV  E
Sbjct: 19928 VDTTDSRTSLTIENANRNDSGKYTLTIQNVLSAASLTLVVKVLDTPGPPTNITVQDVTKE 19987

Query: 954   NVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVF 1013
             +  L+W  P++DG A +  Y I+K +     W +V  + +R S  +T L  G  YYFRV 
Sbjct: 19988 SAVLSWDVPENDGGAPVKNYHIEKREASKKAWVSVTNNCNRLSYKVTNLQEGAIYYFRVS 20047

Query: 1014  SENMCGLSEDATMTKESAVI 1033
              EN  G+   A  TKE   I
Sbjct: 20048 GENEFGVGIPAE-TKEGVKI 20066



 Score =  241 bits (614), Expect = 4e-63
 Identities = 135/381 (35%), Positives = 198/381 (51%), Gaps = 3/381 (0%)

Query: 645   PDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTF 704
             P PP  P VT V  D   ++W  P  DGGSPILGY +ERK++    W  ++  L     F
Sbjct: 14954 PGPPGTPQVTAVTKDSMTISWHEPLSDGGSPILGYHVERKERNGILWQTVSKALVPGNIF 15013

Query: 705   EPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWR 764
             +   + +G+AYE R+ A N  G SKPS PS P + L    PP      ++T  TVT++W 
Sbjct: 15014 KSSGLTDGIAYEFRVIAENMAGKSKPSKPSEPMLALDPIDPPGKPVPLNITRHTVTLKWA 15073

Query: 765   PPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAG 824
              P++ G   +  Y++E        W+ AN   I + +FT++GL  DA    RV A NAAG
Sbjct: 15074 KPEYTGGFKITSYIVEKRDLPNGRWLKANFSNILENEFTVSGLTEDAAYEFRVIAKNAAG 15133

Query: 825   A-SEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKD 883
             A S P   S  I  ++ +E PKI++    K T I + GEA  L     G+P P + W KD
Sbjct: 15134 AISPPSEPSDAITCRDDVEAPKIKVDVKFKDTVILKAGEAFRLEADVSGRPPPTMEWSKD 15193

Query: 884   GAEIDKN-QINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPP 942
             G E++   ++ I+ ++  T +  + + R  SG Y L             +++++DRPGPP
Sbjct: 15194 GKELEGTAKLEIKIADFSTNLVNKDSTRRDSGAYTLTATNPGGFAKHIFNVKVLDRPGPP 15253

Query: 943   Q-IVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITE 1001
             +  + + +V  E   L+W PP DDG A I  Y +QK +   + W  V      T   +T+
Sbjct: 15254 EGPLAVTEVTSEKCVLSWFPPLDDGGAKIDHYIVQKRETSRLAWTNVASEVQVTKLKVTK 15313

Query: 1002  LVIGNEYYFRVFSENMCGLSE 1022
             L+ GNEY FRV + N  G+ E
Sbjct: 15314 LLKGNEYIFRVMAVNKYGVGE 15334



 Score =  240 bits (613), Expect = 5e-63
 Identities = 159/591 (26%), Positives = 282/591 (47%), Gaps = 40/591 (6%)

Query: 454   DLKPLKILTPLTDQTVNLGKEICLKCEISENIPGK--WTKNGLPVQESDRLKVVHKGRIH 511
             D+KP       +  +V +G+++ ++  IS        WTK+GLP++++ R+ V     + 
Sbjct: 16926 DVKPA-----FSSYSVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLT 16980

Query: 512   KLVIANALTEDEGDYVFAPDAYNVTLPAKVHVI-----DPPK--IILDGLDADNTVTVIA 564
              L I     +D G Y            A + ++     DPPK  +  D + A++      
Sbjct: 16981 TLSIKETHKDDGGQYGITVANVVGQKTASIEIVTLDKPDPPKGPVKFDDVSAES------ 17034

Query: 565   GNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRT-----ESYPDSSTLVIDIAERDDS 619
                    I +S  PP      +    I++      T      +    +TL +   +    
Sbjct: 17035 -------ITLSWNPPLYTGGCQITNYIVQKRDTTTTVWDVVSATVARTTLKVTKLKTGTE 17087

Query: 620   GVYHINLKNEAGEAHASIKVKVV-----DFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGS 674
               + I  +N  G++ A     +V       P PP  P  T +  D  ++ W  P  +GGS
Sbjct: 17088 YQFRIFAENRYGQSFALESDPIVAQYPYKEPGPPGTPFATAISKDSMVIQWHEPVNNGGS 17147

Query: 675   PILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPS 734
             P++GY +ERK++ S  W ++N  +  +T F+ + + EG+ YE R++A N +G+ K S  S
Sbjct: 17148 PVIGYHLERKERNSILWTKVNKTIIHDTQFKAQNLEEGIEYEFRVYAENIVGVGKASKNS 17207

Query: 735   RPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANK 794
               +V      PP       V    +T++W  P + G + + GY++E        W+ A+ 
Sbjct: 17208 ECYVARDPCDPPGTPEPIMVKRNEITLQWTKPVYDGGSMITGYIVEKRDLPDGRWMKASF 17267

Query: 795   DLIDKTKFTITGLPTDAKIFVRVKAVNAAGA-SEPKYYSQPILVKEIIEPPKIRIPRHLK 853
               + +T+FT++GL  D +   RV A NAAGA S+P   + PI  K+ +E P+I +    +
Sbjct: 17268 TNVIETQFTVSGLTEDQRYEFRVIAKNAAGAISKPSDSTGPITAKDEVELPRISMDPKFR 17327

Query: 854   QTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKN-QINIRNSETDTIIFIRKAERSH 912
              T +   GE   L     GKP P + W +   EI+++ +  I+N++   ++ ++ A R  
Sbjct: 17328 DTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRID 17387

Query: 913   SGKYDLQVKVDKFVETASIDIQIIDRPGPPQ-IVKIEDVWGENVALTWTPPKDDGNAAIT 971
              G+Y L+       ++  ++++++DRPGPP+  V++  V  E  +LTW+PP  DG + I+
Sbjct: 17388 GGQYILRASNVAGSKSFPVNVKVLDRPGPPEGPVQVTGVTSEKCSLTWSPPLQDGGSDIS 17447

Query: 972   GYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSE 1022
              Y ++K +   + W  V       S  +T+L+ GNEY FR+ + N  G+ E
Sbjct: 17448 HYVVEKRETSRLAWTVVASEVVTNSLKVTKLLEGNEYVFRIMAVNKYGVGE 17498



 Score =  239 bits (611), Expect = 8e-63
 Identities = 148/495 (29%), Positives = 245/495 (49%), Gaps = 10/495 (2%)

Query: 531   DAYNVTLPAK-VHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDK 589
             D+  VT   K V  +  P++ +D  +   T  V AG  +RL I   G P P A+WS+ D 
Sbjct: 22033 DSCEVTGTIKAVDRLTAPELDIDA-NFKQTHVVRAGASIRLFIAYQGRPTPTAVWSKPDS 22091

Query: 590   AIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPV 649
              +   +    T+S+   STL ++   R+D+G Y + ++N +G    +  VKV+D P PP 
Sbjct: 22092 NLSLRADIHTTDSF---STLTVENCNRNDAGKYTLTVENNSGSKSITFTVKVLDTPGPPG 22148

Query: 650   APTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKM 709
               T  +V      + W+ P  DGG+ I  Y +E+++     W  ++ + C    F+   +
Sbjct: 22149 PITFKDVTRGSATLMWDAPLLDGGARIHHYVVEKREASRRSWQVIS-EKCTRQIFKVNDL 22207

Query: 710   IEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHI 769
              EGV Y  R+ AVN  G+ +P     P V     +PP  L V   + ++  + W  PDH 
Sbjct: 22208 AEGVPYYFRVSAVNEYGVGEPYEMPEPIVATEQPAPPRRLDVVDTSKSSAVLAWLKPDHD 22267

Query: 770   GAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPK 829
             G + + GY+LE   +G++ W+ A      +  FT+  L    +   RVKA N AG SEP+
Sbjct: 22268 GGSRITGYLLEMRQKGSDFWVEAGH--TKQLTFTVERLVEKTEYEFRVKAKNDAGYSEPR 22325

Query: 830   YYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEI-D 888
                  +++KE    P   +     Q    + G    + +P  G+P P++TWK +   + +
Sbjct: 22326 EAFSSVIIKEPQIEPTADLTGITNQLITCKAGSPFTIDVPISGRPAPKVTWKLEEMRLKE 22385

Query: 889   KNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGP-PQIVKI 947
              ++++I  ++  T + ++ + R  SG+Y L ++    V+T S+ + +I RPGP    +++
Sbjct: 22386 TDRVSITTTKDRTTLTVKDSMRGDSGRYFLTLENTAGVKTFSVTVVVIGRPGPVTGPIEV 22445

Query: 948   EDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNE 1007
               V  E+  L+W  PKD G   IT Y ++K +  +  W  V     RT   +T L    E
Sbjct: 22446 SSVSAESCVLSWGEPKDGGGTEITNYIVEKRESGTTAWQLVNSSVKRTQIKVTHLTKYME 22505

Query: 1008  YYFRVFSENMCGLSE 1022
             Y FRV SEN  G+S+
Sbjct: 22506 YSFRVSSENRFGVSK 22520



 Score =  238 bits (608), Expect = 2e-62
 Identities = 155/491 (31%), Positives = 238/491 (48%), Gaps = 15/491 (3%)

Query: 544   IDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESY 603
             ++PP++ILD   A     +  G+ LRL   I G P PK  W + D+   +   + R +  
Sbjct: 10908 LEPPELILDANMAREQ-HIKVGDTLRLSAIIKGVPFPKVTWKKEDR---DAPTKARIDVT 10963

Query: 604   PDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIM 663
             P  S L I  A  +D G+Y + ++N AG    S+KV V+D P PP    V+E+  D C +
Sbjct: 10964 PVGSKLEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDKPGPPRDLEVSEIRKDSCYL 11023

Query: 664   NWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVN 723
              W+ P  DGGS I  Y +ER+   S++W  L+    K++ F  K + EG  Y  R+ A N
Sbjct: 11024 TWKEPLDDGGSVITNYVVERRDVASAQWSPLSATSKKKSHF-AKHLNEGNQYLFRVAAEN 11082

Query: 724   AIG---ISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLE 780
               G     +   P +   PL    PP  L    V  T V++ W  PD  G + + GY++E
Sbjct: 11083 QYGRGPFVETPKPIKALDPLHPPGPPKDLHHVDVDKTEVSLVWNKPDRDGGSPITGYLVE 11142

Query: 781   YCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEI 840
             Y  EGT+DWI      +   +  +TGL        RVKA N  G   P   + PI  +E 
Sbjct: 11143 YQEEGTQDWI--KFKTVTNLECVVTGLQQGKTYRFRVKAENIVGLGLPD-TTIPIECQEK 11199

Query: 841   IEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQ-INIRNSET 899
             + PP + +   L +  + + G  V      +G P P   W  DG+EI  ++   +     
Sbjct: 11200 LVPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNF 11259

Query: 900   DTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQ-IVKIEDVWGENVALT 958
              +++ I+   R  +G+Y + V      +T ++ + ++D PGPP   + I DV  E++ ++
Sbjct: 11260 SSVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTVLDVPGPPTGPINILDVTPEHMTIS 11319

Query: 959   WTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMC 1018
             W PPKDDG + +  Y ++K D +   W  V     +T   I  L  G EY FRV +EN  
Sbjct: 11320 WQPPKDDGGSPVINYIVEKQDTRKDTWGVVSSGSSKTKLKIPHLQKGCEYVFRVRAENKI 11379

Query: 1019  GLSE--DATMT 1027
             G+    D+T T
Sbjct: 11380 GVGPPLDSTPT 11390



 Score =  238 bits (607), Expect = 2e-62
 Identities = 169/593 (28%), Positives = 282/593 (47%), Gaps = 27/593 (4%)

Query: 266  LKRMRREEKKSAAFA-------KILDPAYQVDKGGR--VRFVVELADPKLEVKWYKNGQE 316
            L   R E  KSAA         +I++P   ++   +  V F  ++    + +KW KNG+E
Sbjct: 6408 LTNHRGENVKSAANLIVEEEDLRIVEPLKDIETMEKKSVTFWCKVNRLNVTLKWTKNGEE 6467

Query: 317  IRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTELFVREPPIMVTKQLEDT 376
            +    +  +     + +L I +C   D+ EY VTAG +K   EL + E P    + LED 
Sbjct: 6468 VPFDNRVSYRVDKYKHMLTIKDCGFPDEGEYIVTAGQDKSVAELLIIEAPTEFVEHLEDQ 6527

Query: 377  TAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAA 436
            T    +     C++S + ANVKW++NG EI  G K  Y+   +G  H LII+     D  
Sbjct: 6528 TVTEFDDAVFSCQLSREKANVKWYRNGREIKEGKK--YKFEKDGSIHRLIIKDCRLDDEC 6585

Query: 437  EYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCEIS-ENIPGKWTKNGLP 495
            EY+      +S A+L V+  P++I+ P  D     G ++    E++ + +  +W +N + 
Sbjct: 6586 EYACGVEDRKSRARLFVEEIPVEIIRPPQDILEAPGADVVFLAELNKDKVEVQWLRNNMV 6645

Query: 496  VQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKIILDGLD 555
            V + D+ +++ +G+IH+L I +    D+G+Y F   A +    AK+ +   PKI      
Sbjct: 6646 VVQGDKHQMMSEGKIHRLQICDIKPRDQGEYRFI--AKDKEARAKLELAAAPKI----KT 6699

Query: 556  ADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAE 615
            AD  + V  G  L + +P    P  +A W + ++ +   +     ++  + ++  I  A+
Sbjct: 6700 ADQDLVVDVGKPLTMVVPYDAYPKAEAEWFKENEPLSTKT----IDTTAEQTSFRILEAK 6755

Query: 616  RDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSP 675
            + D G Y I L+N+ G+A   I +KV+D P P     VTE  D    + WE P  DGGS 
Sbjct: 6756 KGDKGRYKIVLQNKHGKAEGFINLKVIDVPGPVRNLEVTETFDGEVSLAWEEPLTDGGSK 6815

Query: 676  ILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIE-GVAYEVRIFAVNAIGISKPSMPS 734
            I+GY +ER+  +   W+ L  D  +   F    + + GV Y  R+ A N +G  +P    
Sbjct: 6816 IIGYVVERRDIKRKTWV-LATDRAESCEFTVTGLQKGGVEYLFRVSARNRVGTGEPVETD 6874

Query: 735  RPFVPLA---VTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIV 791
             P    +   V  PP  +T+  V    V++ W PP++ G A +  YV+E   + +  W  
Sbjct: 6875 NPVEARSKYDVPGPPLNVTITDVNRFGVSLTWEPPEYDGGAEITNYVIELRDKTSIRWDT 6934

Query: 792  ANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPP 844
            A     +    T+T +    +   RV+A N  G  +P   +  + V + IE P
Sbjct: 6935 AMTVRAEDLSATVTDVVEGQEYSFRVRAQNRIGVGKPSAATPFVKVADPIERP 6987



 Score =  238 bits (607), Expect = 2e-62
 Identities = 172/634 (27%), Positives = 302/634 (47%), Gaps = 44/634 (6%)

Query: 411   KSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVN 470
             K++Y+ R   +  + I   +  +D    +++         LSV +K L         TV 
Sbjct: 12954 KAQYQFRAIARTAVNISPPSEPSDPV--TILAENVPPRIDLSVAMKSLL--------TVK 13003

Query: 471   LGKEICLKCEI-SENIPG-KWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVF 528
              G  +CL   +  + +P   W K+G  ++ ++ +K+  +  +  L + +   +D GDY  
Sbjct: 13004 AGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTI 13063

Query: 529   APDAYNVTLPA--KVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSR 586
               +  + +  A  K+ V+D P     G  A   +  +  ++  L    S EPP +   S 
Sbjct: 13064 TAENSSGSKSATIKLKVLDKP-----GPPASVKINKMYSDRAML----SWEPPLEDGGSE 13114

Query: 587   GDKAIMEGSGRIRTESYPDSSTLVI---DIAERDDSGVYHINL--KNEAGEA-----HAS 636
                 I++     R      S+T+ I    + +  +   Y   +  +N+ G         +
Sbjct: 13115 ITNYIVDKRETSRPNWAQVSATVPITSCSVEKLIEGHEYQFRICAENKYGVGDPVFTEPA 13174

Query: 637   IKVKVVDFP---DPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMR 693
             I     D P   DPPV   +T+   D   ++W+PPA DGGSPI GY +E+++ Q+  W +
Sbjct: 13175 IAKNPYDPPGRCDPPVISNITK---DHMTVSWKPPADDGGSPITGYLLEKRETQAVNWTK 13231

Query: 694   LNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFV---PLAVTSPPTLLT 750
             +N     E T +   + EG  YE R+ A+N  G  KPS  S+      P     PP    
Sbjct: 13232 VNRKPIIERTLKATGLQEGTEYEFRVTAINKAGPGKPSDASKAAYARDPQYPPGPPAFPK 13291

Query: 751   VDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVAN-KDLIDKTKFTITGLPT 809
             V   T ++V++ W  P + G + + GY++E     +++W+  N    + KT+F +TGL  
Sbjct: 13292 VYDTTRSSVSLSWGKPAYDGGSPIIGYLVEVKRADSDNWVRCNLPQNLQKTRFEVTGLME 13351

Query: 810   DAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIP 869
             D +   RV AVN  G S+P         K+I+ PP+  +   L++T I R G  + L +P
Sbjct: 13352 DTQYQFRVYAVNKIGYSDPSDVPDKHYPKDILIPPEGELDADLRKTLILRAGVTMRLYVP 13411

Query: 870   FQGKPRPELTWKKDGAEI-DKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVET 928
              +G+P P++TW K    + D+  ++I++++ DT +      +  +GKY L ++     + 
Sbjct: 13412 VKGRPPPKITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKYILTLENSCGKKE 13471

Query: 929   ASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTV 988
              +I ++++D PGPP  V ++++  ++  +TW PP  DG + I  Y +QK D +   W TV
Sbjct: 13472 YTIVVKVLDTPGPPVNVTVKEISKDSAYVTWEPPIIDGGSPIINYVVQKRDAERKSWSTV 13531

Query: 989   IEHYHRTSATITELVIGNEYYFRVFSENMCGLSE 1022
                  +TS  +  L  G  Y+FRVF+EN  G+ +
Sbjct: 13532 TTECSKTSFRVANLEEGKSYFFRVFAENEYGIGD 13565



 Score =  238 bits (606), Expect = 3e-62
 Identities = 182/680 (26%), Positives = 309/680 (45%), Gaps = 62/680 (9%)

Query: 389   EVSEDDANVKWFK----NGEEII-------PGPKSRYRIRVEGKKHILIIEGATKADAAE 437
             +VS+  A++ W K     G  ++       P    ++ I  E K    ++ G +     +
Sbjct: 17918 DVSQTSASLMWEKPEHDGGSRVLGYVVEMQPKGTEKWSIVAESKVCNAVVTGLSSGQEYQ 17977

Query: 438   YSVMTTG--GQSSAKL--------SVDLKPLKILTPLTDQTVNLGKEICLKCEI----SE 483
             + V      G+S  ++         + ++P  +  P    ++  G+++ ++  +      
Sbjct: 17978 FRVKAYNEKGKSDPRVLGVPVIAKDLTIQP-SLKLPFNTYSIQAGEDLKIEIPVIGRPRP 18036

Query: 484   NIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAP--DAYNVTLPAKV 541
             NI   W K+G P++++ R+ V        L I     +D G Y       A   T    V
Sbjct: 18037 NI--SWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKYTVTATNSAGTATENLSV 18094

Query: 542   HVIDPP-----KIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSG 596
              V++ P      +  D + AD  V             IS EPP      +    I+E   
Sbjct: 18095 IVLEKPGPPVGPVRFDEVSADFVV-------------ISWEPPAYTGGCQISNYIVEKRD 18141

Query: 597   RIRTESYPDSSTLV---IDIAERDDSGVYHINL--KNEAGE-AHASIKVKVVDFP----D 646
                T  +  S+T+    I I +      Y   +  +N  G+ A    K  +V +P     
Sbjct: 18142 TTTTTWHMVSATVARTTIKITKLKTGTEYQFRIFAENRYGKSAPLDSKAVIVQYPFKEPG 18201

Query: 647   PPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEP 706
             PP  P VT +  D  ++ W  P  DGG+ I+GY +E+K+K S  W++LN    ++T F+ 
Sbjct: 18202 PPGTPFVTSISKDQMLVQWHEPVNDGGTKIIGYHLEQKEKNSILWVKLNKTPIQDTKFKT 18261

Query: 707   KKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPP 766
               + EG+ YE ++ A N +GI KPS  S  FV      PP       +T   VT++W+ P
Sbjct: 18262 TGLDEGLEYEFKVSAENIVGIGKPSKVSECFVARDPCDPPGRPEAIVITRNNVTLKWKKP 18321

Query: 767   DHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAG-A 825
              + G + + GY++E        W+ A+   + +T+FT++GL  D +   RV A NAAG  
Sbjct: 18322 AYDGGSKITGYIVEKKDLPDGRWMKASFTNVLETEFTVSGLVEDQRYEFRVIARNAAGNF 18381

Query: 826   SEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGA 885
             SEP   S  I  ++ I+ P   +    K   +   GE   L    +GKP P++ W KDG 
Sbjct: 18382 SEPSDSSGAITARDEIDAPNASLDPKYKDVIVVHAGETFVLEADIRGKPIPDVVWSKDGK 18441

Query: 886   EIDKN--QINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQ 943
             E+++   ++ I+++   T + ++   R+  G+Y L++      ++  I ++++DRPGPP+
Sbjct: 18442 ELEETAARMEIKSTIQKTTLVVKDCIRTDGGQYILKLSNVGGTKSIPITVKVLDRPGPPE 18501

Query: 944   -IVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITEL 1002
               +K+  V  E   L W PP  DG A I+ Y I+K +   + W  V       +  +T+L
Sbjct: 18502 GPLKVTGVTAEKCYLAWNPPLQDGGANISHYIIEKRETSRLSWTQVSTEVQALNYKVTKL 18561

Query: 1003  VIGNEYYFRVFSENMCGLSE 1022
             + GNEY FRV + N  G+ E
Sbjct: 18562 LPGNEYIFRVMAVNKYGIGE 18581



 Score =  234 bits (598), Expect = 3e-61
 Identities = 141/476 (29%), Positives = 240/476 (50%), Gaps = 11/476 (2%)

Query: 554   LDAD--NTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVI 611
             LDA+   T+ V AG  +R+ +PI G P P+  W++ +  +   +    TES+   + L+I
Sbjct: 14473 LDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKNRANIENTESF---TLLII 14529

Query: 612   DIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYD 671
                 R D+G + + ++N AG+    + V+V+D P P +    T++  D   ++W+ P  D
Sbjct: 14530 PECNRYDTGKFVMTIENPAGKKSGFVNVRVLDTPGPVLNLRPTDITKDSVTLHWDLPLID 14589

Query: 672   GGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPS 731
             GGS I  Y +E+++     +       C + T++   + EG  Y  R+ A N  GI +P+
Sbjct: 14590 GGSRITNYIVEKREATRKSYSTATTK-CHKCTYKVTGLSEGCEYFFRVMAENEYGIGEPT 14648

Query: 732   MPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIV 791
               + P       SPP  L +  +T +TV++ W  P H G + + GYV+E   +G++ W  
Sbjct: 14649 ETTEPVKASEAPSPPDSLNIMDITKSTVSLAWPKPKHDGGSKITGYVIEAQRKGSDQW-- 14706

Query: 792   ANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRH 851
              +   +   +  +  L    +   +V AVN+AG S P+  S+P++VKE    P++ +   
Sbjct: 14707 THITTVKGLECVVRNLTEGEEYTFQVMAVNSAGRSAPR-ESRPVIVKEQTMLPELDLRGI 14765

Query: 852   LKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQ-INIRNSETDTIIFIRKAER 910
              ++  I + G+ + + IP  G+P+P +TWKK    + + Q +N   + T TI+ I +  R
Sbjct: 14766 YQKLVIAKAGDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVR 14825

Query: 911   SHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQ-IVKIEDVWGENVALTWTPPKDDGNAA 969
             S SG Y L  +         I IQ+ D PGPP   +K ++V  + V  +W PP++DG   
Sbjct: 14826 SDSGPYPLTARNIVGEVGDVITIQVHDIPGPPTGPIKFDEVSSDFVTFSWDPPENDGGVP 14885

Query: 970   ITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDAT 1025
             I+ Y ++     S  W  +     RT+   T L  G EY FRV ++N  G+    T
Sbjct: 14886 ISNYVVEMRQTDSTTWVELATTVIRTTYKATRLTTGLEYQFRVKAQNRYGVGPGIT 14941



 Score =  233 bits (595), Expect = 6e-61
 Identities = 168/591 (28%), Positives = 280/591 (47%), Gaps = 38/591 (6%)

Query: 453   VDLKPLKILTPLTDQTVNLGKEICLKCEISENIPGKWTKNGLPVQESDRLKVVHKGRIHK 512
             +DLK   +LT     T+ L  E  ++ +    +     K+   +  S R+K+  +    K
Sbjct: 11898 LDLKLSGVLTVKAGDTIRL--EAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSK 11955

Query: 513   LVIANALTEDEGDYVFAPD--AYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRL 570
               +  A   D G YV      A +    A V+V+D P     G   +  +  ++ ++   
Sbjct: 11956 FSLTKAKRSDGGKYVVTATNTAGSFVAYATVNVLDKP-----GPVRNLKIVDVSSDRCT- 12009

Query: 571   EIPISGEPPPKAMWSRGDKAIMEG--SGRIRTESYPDS----STLVIDIAERDDSGVYHI 624
                +  +PP           I+E   + R+   +Y  +     T V  + E ++  ++ +
Sbjct: 12010 ---VCWDPPEDDGGCEIQNYILEKCETKRMVWSTYSATVLTPGTTVTRLIEGNEY-IFRV 12065

Query: 625   NLKNEAG-----EAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGY 679
               +N+ G     E+   I     D P  P  P VT+V  +   + W PP YDGG  I GY
Sbjct: 12066 RAENKIGTGPPTESKPVIAKTKYDKPGRPDPPEVTKVSKEEMTVVWNPPEYDGGKSITGY 12125

Query: 680   FIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFV- 738
             F+E+K+K S+RW+ +N     E   + + ++    Y+ R+ A N IGI +PS+PSRP V 
Sbjct: 12126 FLEKKEKHSTRWVPVNKSAIPERRMKVQNLLPDHEYQFRVKAENEIGIGEPSLPSRPVVA 12185

Query: 739   --PLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYC-----FEGTEDWIV 791
               P+    PPT   V   T  ++T+ W  P + G A + GYV+E           E W  
Sbjct: 12186 KDPIEPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAPIIGYVVEMRPKIADASPDEGWKR 12245

Query: 792   ANKDL-IDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPR 850
              N    + + +FT+T L  + +   RV A N  G   P    + I  KEI+EPP+I +  
Sbjct: 12246 CNAAAQLVRKEFTVTSLDENQEYEFRVCAQNQVGIGRPAELKEAIKPKEILEPPEIDLDA 12305

Query: 851   HLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAE--IDKNQINIRNSETDTIIFIRKA 908
              +++  I R G  + L    +G+P P++TW+K G +  + K Q+++   +T   + I  +
Sbjct: 12306 SMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVVRKGQVDL--VDTMAFLVIPNS 12363

Query: 909   ERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNA 968
              R  SGKY L +      +   ++++++D PGP   +K+ DV   +  ++W PP++DG +
Sbjct: 12364 TRDDSGKYSLTLVNPAGEKAVFVNVRVLDTPGPVSDLKVSDVTKTSCHVSWAPPENDGGS 12423

Query: 969   AITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCG 1019
              +T Y ++K +     W TV     +TS  +T LV GNEYYFRV + N  G
Sbjct: 12424 QVTHYIVEKREADRKTWSTVTPEVKKTSFHVTNLVPGNEYYFRVTAVNEYG 12474



 Score =  233 bits (594), Expect = 8e-61
 Identities = 159/513 (30%), Positives = 252/513 (49%), Gaps = 34/513 (6%)

Query: 545   DPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWS---RGDKAIMEGSGRI--- 598
             + P++ +D + A + +   AG+++R+   I G P PK+ W    +  KA+ +G   I   
Sbjct: 9501  EEPEVFID-IGAQDCLVCKAGSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPED 9559

Query: 599   -RTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVG 657
              + E+  +SS ++I   +R  +G Y I  KN+AG+  A+ +VKV+D P PP    V+++ 
Sbjct: 9560  AQLETAENSSVIIIPECKRSHTGKYSITAKNKAGQKTANCRVKVMDVPGPPKDLKVSDIT 9619

Query: 658   DDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEV 717
                C ++W+ P  DGG  I GY IE++      W ++N D C  TTF    ++    Y  
Sbjct: 9620  RGSCRLSWKMPDDDGGDRIKGYVIEKRTIDGKAWTKVNPD-CGSTTFVVPDLLSEQQYFF 9678

Query: 718   RIFAVNAIGISKPSMPSRPFV---PLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGL 774
             R+ A N  GI  P    +      P+    PP  L +  +T  TV + W+PP + G + +
Sbjct: 9679  RVRAENRFGIGPPVETIQRTTARDPIYPPDPPIKLKIGLITKNTVHLSWKPPKNDGGSPV 9738

Query: 775   DGYVLEYCF----EGT--EDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEP 828
               Y++E C      GT  E W   NK  +++ +FT+  L    +   RVKAVNAAG S+P
Sbjct: 9739  THYIVE-CLAWDPTGTKKEAWRQCNKRDVEELQFTVEDLVEGGEYEFRVKAVNAAGVSKP 9797

Query: 829   KYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTW------KK 882
                  P   +    PP I     LK+      G  VN+V   +G P P LTW      K 
Sbjct: 9798  SATVGPCDCQRPDMPPSI----DLKEFMEVEEGTNVNIVAKIKGVPFPTLTWFKAPPKKP 9853

Query: 883   DGAE---IDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRP 939
             D  E    D +   +   +T T++ I ++ RS +G Y +    +    +  + + ++ RP
Sbjct: 9854  DNKEPVLYDTHVNKLVVDDTCTLV-IPQSRRSDTGLYTITAVNNLGTASKEMRLNVLGRP 9912

Query: 940   GPP-QIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSAT 998
             GPP   +K E V  + + L+W PPKDDG + IT Y I+K +     W  V       + T
Sbjct: 9913  GPPVGPIKFESVSADQMTLSWFPPKDDGGSKITNYVIEKREANRKTWVHVSSEPKECTYT 9972

Query: 999   ITELVIGNEYYFRVFSENMCGLSEDATMTKESA 1031
             I +L+ G+EY FR+ ++N  G+ E      E+A
Sbjct: 9973  IPKLLEGHEYVFRIMAQNKYGIGEPLDSEPETA 10005



 Score =  230 bits (587), Expect = 5e-60
 Identities = 156/568 (27%), Positives = 267/568 (47%), Gaps = 24/568 (4%)

Query: 490   TKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKI 549
             +++G+P++ + R           + +  ++T D G Y       + T  A ++++     
Sbjct: 20206 SRDGVPLKATMRFNTEITAENLTINLKESVTADAGRYEITAANSSGTTKAFINIV----- 20260

Query: 550   ILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIM---EGSGRIRTESYPDS 606
             +LD      T  V+  +     + +  EPP     S+    I+   E S  + TE     
Sbjct: 20261 VLDR-PGPPTGPVVISDITEESVTLKWEPPKYDGGSQVTNYILLKRETSTAVWTEVSATV 20319

Query: 607   STLVIDIAERDDSGVYHINLKNE--------AGEAHASIKVKVVDFPDPPVAPTVTEVGD 658
             +  ++ + +      Y   +K E           A  ++K+     P PP  P VT V  
Sbjct: 20320 ARTMMKVMKLTTGEEYQFRIKAENRFGISDHIDSACVTVKLPYTT-PGPPSTPWVTNVTR 20378

Query: 659   DWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVR 718
             +   + W  P  +GGS ++GY +E K + S  W + N  + + T F+   +  G+ YE R
Sbjct: 20379 ESITVGWHEPVSNGGSAVVGYHLEMKDRNSILWQKANKLVIRTTHFKVTTISAGLIYEFR 20438

Query: 719   IFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYV 778
             ++A NA G+ KPS PS P + +    PP  + +  ++  +V++ W+ P   G + + GY+
Sbjct: 20439 VYAENAAGVGKPSHPSEPVLAIDACEPPRNVRITDISKNSVSLSWQQPAFDGGSKITGYI 20498

Query: 779   LEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGA-SEPKYYSQPILV 837
             +E        W  A+   + +T+F I+GL  +++   RV A NA G+ S P     PI  
Sbjct: 20499 VERRDLPDGRWTKASFTNVTETQFIISGLTQNSQYEFRVFARNAVGSISNPSEVVGPITC 20558

Query: 838   KEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNS 897
              +    P I +P    +    R G +V L     GKP P + W KD  E+  N +    +
Sbjct: 20559 IDSYGGPVIDLPLEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVEN 20618

Query: 898   ETD-TIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPP-QIVKIEDVWGENV 955
              TD   I I+ A+R +SG Y+L+++      +A+I +QI+D+PGPP   ++ + V  E +
Sbjct: 20619 TTDLASILIKDADRLNSGCYELKLRNAMGSASATIRVQILDKPGPPGGPIEFKTVTAEKI 20678

Query: 956   ALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSE 1015
              L W PP DDG A IT Y ++K +   + W  V EH      T T+++ GNEY FRV + 
Sbjct: 20679 TLLWRPPADDGGAKITHYIVEKRETSRVVWSMVSEHLEECIITTTKIIKGNEYIFRVRAV 20738

Query: 1016  NMCGLSEDATMTKESAVIARDGKIYKNP 1043
             N  G+ E     +  +V+A++  +   P
Sbjct: 20739 NKYGIGEP---LESDSVVAKNAFVTPGP 20763



 Score =  230 bits (586), Expect = 7e-60
 Identities = 161/526 (30%), Positives = 248/526 (47%), Gaps = 48/526 (9%)

Query: 545  DPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYP 604
            + P+I LD +     +TV AG K+ L   ++G+P PK  W++ D  I++   RI  E+ P
Sbjct: 7381 EAPEIFLD-VKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADM-ILKQDKRITIENVP 7438

Query: 605  DSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMN 664
              ST+ I  ++R D+G Y I   N  G A A ++V V+D P PP A  +T+V ++ C++ 
Sbjct: 7439 KKSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNVLDKPGPPAAFDITDVTNESCLLT 7498

Query: 665  WEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNA 724
            W PP  DGGS I  Y +ER+   S  W +L+    K+T F+  K+I    Y  R+ A N 
Sbjct: 7499 WNPPRDDGGSKITNYVVERRATDSEVWHKLS-STVKDTNFKATKLIPNKEYIFRVAAENM 7557

Query: 725  IGISKP--SMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYC 782
             G+ +P  + P           PPT L    +T   VT+ W  PD  G + + GY +E  
Sbjct: 7558 YGVGEPVQASPITAKYQFDPPGPPTRLEPSDITKDAVTLTWCEPDDDGGSPITGYWVERL 7617

Query: 783  FEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIE 842
               T+ W+  NK  +  T + + GL    K   RV A N AG  +P   ++PIL+K+ I+
Sbjct: 7618 DPDTDKWVRCNKMPVKDTTYRVKGLTNKKKYRFRVLAENLAGPGKPSKSTEPILIKDPID 7677

Query: 843  PPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKK----DGAEIDKNQINIRNSE 898
            PP       +K                  GK    L W K     GA+I+   I +  + 
Sbjct: 7678 PPWPPGKPTVKDV----------------GKTSVRLNWTKPEHDGGAKIESYVIEMLKTG 7721

Query: 899  TDTIIFIRKAE-----------RSHSGKYDLQVK-VDKFVETASID-------IQIIDRP 939
            TD   ++R AE                +Y  +V+ V+K  E+   +        + +  P
Sbjct: 7722 TDE--WVRVAEGVPTTQHLLPGLMEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPP 7779

Query: 940  GPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATI 999
             PP+ +++ ++      L WT P+ DG + IT Y ++K D +   W TV      T  T+
Sbjct: 7780 SPPRWLEVINITKNTADLKWTVPEKDGGSPITNYIVEKRDVRRKGWQTVDTTVKDTKCTV 7839

Query: 1000 TELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVY 1045
            T L  G+ Y FRV +EN  G S+   +  E +V+A+D      P Y
Sbjct: 7840 TPLTEGSLYVFRVAAENAIGQSDYTEI--EDSVLAKDTFTTPGPPY 7883



 Score =  230 bits (586), Expect = 7e-60
 Identities = 154/553 (27%), Positives = 257/553 (46%), Gaps = 32/553 (5%)

Query: 489   WTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVF--APDAYNVTLPAKVHVIDP 546
             W K+G  ++E+ R+ V     +  L I  A  ED G Y    +  A ++T+P  + V+D 
Sbjct: 19123 WRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSNSAGSITVPITIIVLDR 19182

Query: 547   P----KIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTES 602
             P     I +D +  D+             I IS  PP      +    I+E      T  
Sbjct: 19183 PGPPGPIRIDEVSCDS-------------ITISWNPPEYDGGCQISNYIVEKKETTSTTW 19229

Query: 603   YPDSSTLV---IDIAERDDSGVYHINL-------KNEAGEAHASIKVKVVDFPDPPVAPT 652
             +  S  +    I I        Y   +       K+   E+ A +       P PP  P 
Sbjct: 19230 HIVSQAVARTSIKIVRLTTGSEYQFRVCAENRYGKSSYSESSAVVAEYPFSPPGPPGTPK 19289

Query: 653   VTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEG 712
             V        ++ W+ P  DGGS ++GY +E K++ S  W + N  L  +T  +   + EG
Sbjct: 19290 VVHATKSTMLVTWQVPVNDGGSRVIGYHLEYKERSSILWSKANKILIADTQMKVSGLDEG 19349

Query: 713   VAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAA 772
             + YE R++A N  GI K S    P        PP    V ++T  +V+++W  P + G A
Sbjct: 19350 LMYEYRVYAENIAGIGKCSKSCEPVPARDPCDPPGQPEVTNITRKSVSLKWSKPHYDGGA 19409

Query: 773   GLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAA-GASEPKYY 831
              + GY++E        W+  N   I +T F +T L  D +   RV A NAA   SEP   
Sbjct: 19410 KITGYIVERRELPDGRWLKCNYTNIQETYFEVTELTEDQRYEFRVFARNAADSVSEPSES 19469

Query: 832   SQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKN- 890
             + PI+VK+ +EPP++ +    +   + + GE + +     G+P P ++W KDG EI++  
Sbjct: 19470 TGPIIVKDDVEPPRVMMDVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERA 19529

Query: 891   QINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQ-IVKIED 949
             +  I +++  T++ ++   R  +G+Y L +K      + +++ +++D+PGPP   ++I  
Sbjct: 19530 RTEIISTDNHTLLTVKDCIRRDTGQYVLTLKNVAGTRSVAVNCKVLDKPGPPAGPLEING 19589

Query: 950   VWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYY 1009
             +  E  +L+W  P++DG A I  Y ++K +   + W         TS  +T+L+ GNEY 
Sbjct: 19590 LTAEKCSLSWGRPQEDGGADIDYYIVEKRETSHLAWTICEGELQMTSCKVTKLLKGNEYI 19649

Query: 1010  FRVFSENMCGLSE 1022
             FRV   N  G+ E
Sbjct: 19650 FRVTGVNKYGVGE 19662



 Score =  229 bits (583), Expect = 1e-59
 Identities = 169/620 (27%), Positives = 271/620 (43%), Gaps = 26/620 (4%)

Query: 419   EGKKHILIIEGATKADAAEYSVMTTGGQSSAKL-SVDLKPLKILTPLTDQTVNLGKEICL 477
             EGK++   +    +      S +T   +       +DLK L  L  L  +  N   +I +
Sbjct: 13642 EGKEYTFRVSAENENGEGTPSEITVVARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPI 13701

Query: 478   KCEISENIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTL 537
             K + + ++   W K   P+    R+ V        L++ +    D G Y         T 
Sbjct: 13702 KGKPAPSV--SWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTK 13759

Query: 538   PA--KVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGS 595
                  + V+  P I    +  D  VT  A       + +   PP     S     I+E  
Sbjct: 13760 EGTISIKVVGKPGIPTGPIKFDE-VTAEA-------MTLKWAPPKDDGGSEITNYILEKR 13811

Query: 596   GRIRTE-----SYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVV-----DFP 645
               +  +     S    +T  +          + ++ +N+ G         +V     D P
Sbjct: 13812 DSVNNKWVTCASAVQKTTFRVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVP 13871

Query: 646   DPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFE 705
             D P  P + +V  D   + W  P   GGSPI GY +E K++ S  W R N    +   F+
Sbjct: 13872 DAPPPPNIVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTPIRMRDFK 13931

Query: 706   PKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRP 765
                + EG+ YE R+ A+N  G+ KPS+PS P V L    PP    V ++T  +VT+ W  
Sbjct: 13932 VTGLTEGLEYEFRVMAINLAGVGKPSLPSEPVVALDPIDPPGKPEVINITRNSVTLIWTE 13991

Query: 766   PDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGA 825
             P + G   L GY++E     ++ W+ AN   + +  FT+T L    K   R++A N AGA
Sbjct: 13992 PKYDGGHKLTGYIVEKRDLPSKSWMKANHVNVPECAFTVTDLVEGGKYEFRIRAKNTAGA 14051

Query: 826   -SEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNL-VIPFQGKPRPELTWKKD 883
              S P   ++ I+ K+  E P I +   +K     + G+ + L  I   GKP P+ +W K 
Sbjct: 14052 ISAPSESTETIICKDEYEAPTIVLDPTIKDGLTIKAGDTIVLNAISILGKPLPKSSWSKA 14111

Query: 884   GAEIDKNQI-NIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPP 942
             G +I  + I  I ++ T +++ I+ A R  +G+Y +        +   + + ++D PGPP
Sbjct: 14112 GKDIRPSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFGTKVEHVKVTVLDVPGPP 14171

Query: 943   QIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITEL 1002
               V+I +V  E   LTWTPP +DG + I  Y ++K +   + W  V E         T+L
Sbjct: 14172 GPVEISNVSAEKATLTWTPPLEDGGSPIKSYILEKRETSRLLWTVVSEDIQSCRHVATKL 14231

Query: 1003  VIGNEYYFRVFSENMCGLSE 1022
             + GNEY FRV + N  G  E
Sbjct: 14232 IQGNEYIFRVSAVNHYGKGE 14251



 Score =  228 bits (580), Expect = 3e-59
 Identities = 170/617 (27%), Positives = 288/617 (46%), Gaps = 47/617 (7%)

Query: 453   VDLKPLKILTPLTDQTV-NLGKEICLKCEISENIPG--KWTKNGLPVQESDRLKVVHKGR 509
             V+   +K+     D  +   G+   L+ ++S   P   +W+K+G  ++ + +L++     
Sbjct: 15151 VEAPKIKVDVKFKDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADF 15210

Query: 510   IHKLVIANALTEDEGDYV--------FAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVT 561
                LV  ++   D G Y         FA   +NV       V+D P       +    VT
Sbjct: 15211 STNLVNKDSTRRDSGAYTLTATNPGGFAKHIFNVK------VLDRP----GPPEGPLAVT 15260

Query: 562   VIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIR-----TESYPDSSTLVIDIAER 616
              +   K  L    S  PP     ++ D  I++     R       S    + L +    +
Sbjct: 15261 EVTSEKCVL----SWFPPLDDGGAKIDHYIVQKRETSRLAWTNVASEVQVTKLKVTKLLK 15316

Query: 617   DDSGVYHINLKNEAG-----EAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYD 671
              +  ++ +   N+ G     E+   + V     PDPP  P VT +  D  ++ W  P  D
Sbjct: 15317 GNEYIFRVMAVNKYGVGEPLESEPVLAVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDSD 15376

Query: 672   GGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPS 731
             GGS I+ Y +ER+ K   RW++ N     +  ++   + EG  YE RI A NA GIS PS
Sbjct: 15377 GGSEIINYIVERRDKAGQRWIKCNKKTLTDLRYKVSGLTEGHEYEFRIMAENAAGISAPS 15436

Query: 732   MPSRPFVPLAVT----SPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTE 787
              P+ PF     T     PP    V   + +++++ W  P + G + + GY++E      +
Sbjct: 15437 -PTSPFYKACDTVFKPGPPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIALPEED 15495

Query: 788   DW-IVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKI 846
             +W IV     +  T +TITGL  + +  +R+ A+N+ G  EP         ++ + PP+I
Sbjct: 15496 EWQIVTPPAGLKATSYTITGLTENQEYKIRIYAMNSEGLGEPALVPGTPKAEDRMLPPEI 15555

Query: 847   RIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKD-GAEIDKNQINIRNSETDTIIFI 905
              +   L++    R    + L +P +G+P PE+ W +D G  +DK   +I ++ + T++ +
Sbjct: 15556 ELDADLRKVVTIRACCTLRLFVPIKGRPAPEVKWARDHGESLDK--ASIESTSSYTLLIV 15613

Query: 906   RKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDD 965
                 R  SGKY L V+     ++A ++++++D PGPPQ +K+++V   +V LTW PP  D
Sbjct: 15614 GNVNRFDSGKYILTVENSSGSKSAFVNVRVLDTPGPPQDLKVKEVTKTSVTLTWDPPLLD 15673

Query: 966   GNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGL---SE 1022
             G + I  Y ++K +     + TV  + H+TS  + +L  G  YYFRV +EN  G+   +E
Sbjct: 15674 GGSKIKNYIVEKRESTRKAYSTVATNCHKTSWKVDQLQEGCSYYFRVLAENEYGIGLPAE 15733

Query: 1023  DATMTKESAVIARDGKI 1039
              A   K S      GKI
Sbjct: 15734 TAESVKASERPLPPGKI 15750



 Score =  228 bits (580), Expect = 3e-59
 Identities = 151/547 (27%), Positives = 256/547 (46%), Gaps = 24/547 (4%)

Query: 489   WTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPD--AYNVTLPAKVHVIDP 546
             W K+GLP++ES+ ++         L I NA  E  G Y    D     + +P  V  + P
Sbjct: 21292 WLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGGKYTVILDNAVCRIAVPITVITLGP 21351

Query: 547   PK-----IILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTE 601
             P      I  D + AD+ +       L  ++P          +S   +   + + ++   
Sbjct: 21352 PSKPKGPIRFDEIKADSVI-------LSWDVPEDNGGGEITCYSIEKRETSQTNWKMVCS 21404

Query: 602   SYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVD-----FPDPPVAPTVTEV 656
             S   ++  V ++  +D    + +  +N  G +   +   +V       P PP  P +  V
Sbjct: 21405 SVARTTFKVPNLV-KDAEYQFRVRAENRYGVSQPLVSSIIVAKHQFRIPGPPGKPVIYNV 21463

Query: 657   GDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYE 716
               D   + W+ P YDGGS + G+ +E+K++ S  W ++N        +    ++EG+ Y+
Sbjct: 21464 TSDGMSLTWDAPVYDGGSEVTGFHVEKKERNSILWQKVNTSPISGREYRATGLVEGLDYQ 21523

Query: 717   VRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDG 776
              R++A N+ G+S PS PS+  + ++   PP       VT  T+T++W PP   G + + G
Sbjct: 21524 FRVYAENSAGLSSPSDPSKFTLAVSPVDPPGTPDYIDVTRETITLKWNPPLRDGGSKIVG 21583

Query: 777   YVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGA-SEPKYYSQPI 835
             Y +E   +G E W+  N   + + ++T+TGL    +   R+ A NA G  S P   S  I
Sbjct: 21584 YSIEK-RQGNERWVRCNFTDVSECQYTVTGLSPGDRYEFRIIARNAVGTISPPSQSSGII 21642

Query: 836   LVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKN-QINI 894
             + ++   PP +          I + GE++ +    QG+P P +TW KDG EI+K   + I
Sbjct: 21643 MTRDENVPPIVEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEI 21702

Query: 895   RNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGP-PQIVKIEDVWGE 953
              +    T +F+R A R H G Y ++ K       A I +++ D PG     ++  ++ GE
Sbjct: 21703 TDVLGSTSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQDTPGKVVGPIRFTNITGE 21762

Query: 954   NVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVF 1013
              + L W  P +DG A IT Y I+K +   + W  + +     S T  +L+ GNEY FRV 
Sbjct: 21763 KMTLWWDAPLNDGCAPITHYIIEKRETSRLAWALIEDKCEAQSYTAIKLINGNEYQFRVS 21822

Query: 1014  SENMCGL 1020
             + N  G+
Sbjct: 21823 AVNKFGV 21829



 Score =  227 bits (578), Expect = 6e-59
 Identities = 154/500 (30%), Positives = 249/500 (49%), Gaps = 18/500 (3%)

Query: 530   PDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDK 589
             P   N  + AK  +++ P+I LD +    +V   AG  +++ IP  G PPP   W R D+
Sbjct: 20948 PIEMNEPVQAK-DILEAPEIDLD-VALRTSVIAKAGEDVQVLIPFKGRPPPTVTW-RKDE 21004

Query: 590   AIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHAS-IKVKVVDFPDPP 648
               +    R   E+   SS L I    R+D+G Y + ++N  GE  +S + VKV+D P   
Sbjct: 21005 KNLGSDARYSIENTDSSSLLTIPQVTRNDTGKYILTIENGVGEPKSSTVSVKVLDTPAAC 21064

Query: 649   VAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKK 708
                 V  V      + W+PP  DGGSPI+ Y IE++      W  ++   C  T+F+   
Sbjct: 21065 QKLQVKHVSRGTVTLLWDPPLIDGGSPIINYVIEKRDATKRTWSVVSHK-CSSTSFKLID 21123

Query: 709   MIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDH 768
             + E   +  R+ A N IGI +P   + P     V +P   L++   T T+V + W  PD 
Sbjct: 21124 LSEKTPFFFRVLAENEIGIGEPCETTEPVKAAEVPAPIRDLSMKDSTKTSVILSWTKPDF 21183

Query: 769   IGAAGLDGYVLEYCFEGTEDWIVANKDLIDKT-KFTITGLPTDAKIFVRVKAVNAAGASE 827
              G + +  YV+E   +G + W  A    I KT +  ++ L   + +  RV A N  G S+
Sbjct: 21184 DGGSVITEYVVERKGKGEQTWSHAG---ISKTCEIEVSQLKEQSVLEFRVFAKNEKGLSD 21240

Query: 828   PKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEI 887
             P     PI VKE+I  P++ +          R+G  V+L +P++GKP+P ++W KDG  +
Sbjct: 21241 PVTIG-PITVKELIITPEVDLSDIPGAQVTVRIGHNVHLELPYKGKPKPSISWLKDGLPL 21299

Query: 888   DKNQ-INIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQI-- 944
              +++ +    +E    + I+ A++ H GKY   V +D  V   ++ I +I   GPP    
Sbjct: 21300 KESEFVRFSKTENKITLSIKNAKKEHGGKYT--VILDNAVCRIAVPITVITL-GPPSKPK 21356

Query: 945   --VKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITEL 1002
               ++ +++  ++V L+W  P+D+G   IT Y+I+K +     W  V     RT+  +  L
Sbjct: 21357 GPIRFDEIKADSVILSWDVPEDNGGGEITCYSIEKRETSQTNWKMVCSSVARTTFKVPNL 21416

Query: 1003  VIGNEYYFRVFSENMCGLSE 1022
             V   EY FRV +EN  G+S+
Sbjct: 21417 VKDAEYQFRVRAENRYGVSQ 21436



 Score =  226 bits (576), Expect = 1e-58
 Identities = 163/554 (29%), Positives = 261/554 (47%), Gaps = 33/554 (5%)

Query: 489   WTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYV--FAPDAYNVTLPAKVHVIDP 546
             W K+ +P++++ R+          L I +A  ED G YV      A        V V+D 
Sbjct: 15876 WHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAGEAIETLNVIVLDK 15935

Query: 547   P-----KIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTE 601
             P      + +D + AD+             I +S  PP     S  +  I+E      T 
Sbjct: 15936 PGPPTGPVKMDEVTADS-------------ITLSWGPPKYDGGSSINNYIVEKRDTSTTT 15982

Query: 602   SYPDSSTLVIDI--AERDDSGV---YHINLKNEAGEA-HASIKVKVVDF----PDPPVAP 651
                 S+T+      A R  +G    + I  +N  G++ + + +  V  +    P PP  P
Sbjct: 15983 WQIVSATVARTTIKACRLKTGCEYQFRIAAENRYGKSTYLNSEPTVAQYPFKVPGPPGTP 16042

Query: 652   TVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIE 711
              VT    D   + W  P  DGGS ++GY +ERK++ S  W++LN     +T F+   + E
Sbjct: 16043 VVTLSSRDSMEVQWNEPISDGGSRVIGYHLERKERNSILWVKLNKTPIPQTKFKTTGLEE 16102

Query: 712   GVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGA 771
             GV YE R+ A N +GI KPS  S  +V      PP       VT  +VT++W+ P + G 
Sbjct: 16103 GVEYEFRVSAENIVGIGKPSKVSECYVARDPCDPPGRPEAIIVTRNSVTLQWKKPTYDGG 16162

Query: 772   AGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGA-SEPKY 830
             + + GY++E        W+ A+   I  T F +TGL  D +   RV A NAAG  SEP  
Sbjct: 16163 SKITGYIVEKKELPEGRWMKASFTNIIDTHFEVTGLVEDHRYEFRVIARNAAGVFSEPSE 16222

Query: 831   YSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKN 890
              +  I  ++ ++PP+I +    K T +   GE+  +     GKP P + W K   E+   
Sbjct: 16223 STGAITARDEVDPPRISMDPKYKDTIVVHAGESFKVDADIYGKPIPTIQWIKGDQELSNT 16282

Query: 891   -QINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQ-IVKIE 948
              ++ I++++  T + ++ A R  SG Y L+ K      + +++++++DRPGPP+  V I 
Sbjct: 16283 ARLEIKSTDFATSLSVKDAVRVDSGNYILKAKNVAGERSVTVNVKVLDRPGPPEGPVVIS 16342

Query: 949   DVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEY 1008
              V  E   L W PP  DG + I  Y +++ +   + W  V  +    S  +T+L+ GNEY
Sbjct: 16343 GVTAEKCTLAWKPPLQDGGSDIINYIVERRETSRLVWTVVDANVQTLSCKVTKLLEGNEY 16402

Query: 1009  YFRVFSENMCGLSE 1022
              FR+ + N  G+ E
Sbjct: 16403 TFRIMAVNKYGVGE 16416



 Score =  225 bits (574), Expect = 2e-58
 Identities = 142/476 (29%), Positives = 224/476 (47%), Gaps = 18/476 (3%)

Query: 598   IRTESYPDSSTLVIDIAERDDSGVYHINLKNEAG-----EAHASIKVKVVDFPDPPVAPT 652
             +   S P   T  I         V+ I  +N+ G     ++       +   P  P  PT
Sbjct: 9960  VHVSSEPKECTYTIPKLLEGHEYVFRIMAQNKYGIGEPLDSEPETARNLFSVPGAPDKPT 10019

Query: 653   VTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETT----FEPKK 708
             V+ V  +   +NWE P YDGGSP+ GY++E K   S RW R+N D  K  T    ++   
Sbjct: 10020 VSSVTRNSMTVNWEEPEYDGGSPVTGYWLEMKDTTSKRWKRVNRDPIKAMTLGVSYKVTG 10079

Query: 709   MIEGVAYEVRIFAVNAIGISKPSMPSRPFV---PLAVTSPPTLLTVDSVTDTTVTMRWRP 765
             +IEG  Y+ R++A+NA G+   S+PS P     P+A   PP     D  T ++  + W P
Sbjct: 10080 LIEGSDYQFRVYAINAAGVGPASLPSDPATARDPIAPPGPPFPKVTDW-TKSSADLEWSP 10138

Query: 766   PDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGA 825
             P   G + + GY++EY  EG E+W       +  TK  +TGL   A    RV+AVN AG 
Sbjct: 10139 PLKDGGSKVTGYIVEYKEEGKEEWEKGKDKEVRGTKLVVTGLKEGAFYKFRVRAVNIAGI 10198

Query: 826   SEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGA 885
              EP   +  I +K+ +  P +++   ++   +   G  + ++    GKP P +TW  +  
Sbjct: 10199 GEPGEVTDVIEMKDRLVSPDLQLDASVRDRIVVHAGGVIRIIAYVSGKPPPTVTWNMNER 10258

Query: 886   EIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIV 945
              + + +  I  +   + + I+  +RSH G Y L  K +      +I + ++D PGP    
Sbjct: 10259 TLPQ-EATIETTAISSSMVIKNCQRSHQGVYSLLAKNEAGERKKTIIVDVLDVPGPVGTP 10317

Query: 946   KI-EDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVI 1004
              +  ++  E+  LTW  P+DDG + IT Y I+K +     W  V     R +AT+  L+ 
Sbjct: 10318 FLAHNLTNESCKLTWFSPEDDGGSPITNYVIEKRESDRRAWTPVTYTVTRQNATVQGLIQ 10377

Query: 1005  GNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPL 1060
             G  Y+FR+ +EN  G+      T E+ VI     + + P  ED +  E    T  L
Sbjct: 10378 GKAYFFRIAAENSIGMG-PFVETSEALVIREPITVPERP--EDLEVKEVTKNTVTL 10430



 Score =  223 bits (569), Expect = 6e-58
 Identities = 160/574 (27%), Positives = 265/574 (46%), Gaps = 34/574 (5%)

Query: 488   KWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNV----TLPAKVHV 543
             +W K    +  + RL++        L + +A+  D G+Y+    A NV    ++   V V
Sbjct: 16271 QWIKGDQELSNTARLEIKSTDFATSLSVKDAVRVDSGNYILK--AKNVAGERSVTVNVKV 16328

Query: 544   IDPP-----KIILDGLDADNTVTVIA-----GNKLRLEIPISGEPPPKAMWSRGDKAIME 593
             +D P      +++ G+ A+            G    +   +      + +W+  D  +  
Sbjct: 16329 LDRPGPPEGPVVISGVTAEKCTLAWKPPLQDGGSDIINYIVERRETSRLVWTVVDANVQT 16388

Query: 594   GSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTV 653
              S ++      +  T  I    +   G        E  E+   +       PD P AP V
Sbjct: 16389 LSCKVTKLLEGNEYTFRIMAVNKYGVG--------EPLESEPVVAKNPFVVPDAPKAPEV 16440

Query: 654   TEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGV 713
             T V  D  I+ WE PA DGGS ILGY +E++ K+  RW R +  L  E       +IE  
Sbjct: 16441 TTVTKDSMIVVWERPASDGGSEILGYVLEKRDKEGIRWTRCHKRLIGELRLRVTGLIENH 16500

Query: 714   AYEVRIFAVNAIGISKPSMPS---RPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIG 770
              YE R+ A NA G+S+PS PS   +   P+    PP    V  +T ++V + W  P + G
Sbjct: 16501 DYEFRVSAENAAGLSEPSPPSAYQKACDPIYKPGPPNNPKVIDITRSSVFLSWSKPIYDG 16560

Query: 771   AAGLDGYVLEYCFEGTEDWIVANKDL-IDKTKFTITGLPTDAKIFVRVKAVNAAGASEPK 829
                + GY++E C     +W +      I+KT   +  L    +   R+ A+N AG  E  
Sbjct: 16561 GCEIQGYIVEKCDVSVGEWTMCTPPTGINKTNIEVEKLLEKHEYNFRICAINKAGVGEHA 16620

Query: 830   YYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTW-KKDGAEID 888
                 PI+V+E +E P I +   L++    R G ++ L +P +G+P PE+ W K DG   D
Sbjct: 16621 DVPGPIIVEEKLEAPDIDLDLELRKIINIRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRD 16680

Query: 889   KNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIE 948
                I++ +S T  +  +    R  SGKY L ++     ++A + ++++D P PP  +K+ 
Sbjct: 16681 AAIIDVTSSFTSLV--LDNVNRYDSGKYTLTLENSSGTKSAFVTVRVLDTPSPPVNLKVT 16738

Query: 949   DVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEY 1008
             ++  ++V++TW PP  DG + I  Y ++K +     +  V+ + H+ S  I +L  G  Y
Sbjct: 16739 EITKDSVSITWEPPLLDGGSKIKNYIVEKREATRKSYAAVVTNCHKNSWKIDQLQEGCSY 16798

Query: 1009  YFRVFSENMCGL---SEDATMTKESAVIARDGKI 1039
             YFRV +EN  G+   ++ A   K + V    GKI
Sbjct: 16799 YFRVTAENEYGIGLPAQTADPIKVAEVPQPPGKI 16832



 Score =  222 bits (566), Expect = 1e-57
 Identities = 161/583 (27%), Positives = 256/583 (43%), Gaps = 22/583 (3%)

Query: 455   LKPLKILTPLTDQTVNLGKEICLKCEI--SENIPGKWTKNGLPVQESDRLKVVHKGRIHK 512
             L P KIL P    T+  GK++ ++  +    +   KW K    V  S  L V        
Sbjct: 12592 LLPPKILMP-EQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSI 12650

Query: 513   LVIANALTEDEGDYVFAPDAYNVTLPAKVHVI-----DPPKIILDGLDADNTVTVIAGNK 567
             L+I +   +D G Y    +  + T   K+ V+      PP+   D  D D          
Sbjct: 12651 LIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPGPPQPPFDISDIDADAC-----S 12705

Query: 568   LRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLK 627
             L   IP+         +      +  G       S   +S  V  +    +  ++ +  +
Sbjct: 12706 LSWHIPLEDGGSNITNYIVEKCDVSRGDWVTALASVTKTSCRVGKLIPGQEY-IFRVRAE 12764

Query: 628   NEAGEAHASIKVKVV-----DFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIE 682
             N  G +      K+V       P  P    VT+V  D   + W+ P  DGGSPI+GY IE
Sbjct: 12765 NRFGISEPLTSPKMVAQFPFGVPSEPKNARVTKVNKDCIFVAWDRPDSDGGSPIIGYLIE 12824

Query: 683   RKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAV 742
             RK++ S  W++ N  L + T +    ++EG+ Y  RI+A+N  G S PS P+        
Sbjct: 12825 RKERNSLLWVKANDTLVRSTEYPCAGLVEGLEYSFRIYALNKAGSSPPSKPTEYVTARMP 12884

Query: 743   TSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVAN--KDLIDKT 800
               PP    V  VT +TV++ W  P H G + + GY +E C    + W+  N     I + 
Sbjct: 12885 VDPPGKPEVIDVTKSTVSLIWARPKHDGGSKIIGYFVEACKLPGDKWVRCNTAPHQIPQE 12944

Query: 801   KFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRV 860
             ++T TGL   A+   R  A  A   S P   S P+ +     PP+I +   +K     + 
Sbjct: 12945 EYTATGLEEKAQYQFRAIARTAVNISPPSEPSDPVTILAENVPPRIDLSVAMKSLLTVKA 13004

Query: 861   GEAVNLVIPFQGKPRPELTWKKDGAEIDKNQ-INIRNSETDTIIFIRKAERSHSGKYDLQ 919
             G  V L     GKP P ++WKKDG  +   + I +        + +    R  SG Y + 
Sbjct: 13005 GTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTIT 13064

Query: 920   VKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKAD 979
              +     ++A+I ++++D+PGPP  VKI  ++ +   L+W PP +DG + IT Y + K +
Sbjct: 13065 AENSSGSKSATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYIVDKRE 13124

Query: 980   KKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSE 1022
                  W  V      TS ++ +L+ G+EY FR+ +EN  G+ +
Sbjct: 13125 TSRPNWAQVSATVPITSCSVEKLIEGHEYQFRICAENKYGVGD 13167



 Score =  222 bits (565), Expect = 2e-57
 Identities = 160/535 (29%), Positives = 257/535 (48%), Gaps = 52/535 (9%)

Query: 527  VFAPDAYNVTLPAKV--HVI--DP---PKIILDGLDADNTVTVIAGNKLRLEIPISGEPP 579
            V A +A  V+ P+++  +V+  DP   P I L+  D    + VI G KL + +P    P 
Sbjct: 8055 VRAVNAIGVSEPSEISENVVAKDPDCKPTIDLETHD----IIVIEGEKLSIPVPFRAVPV 8110

Query: 580  PKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKV 639
            P   W +  K + + S R+  ++   S+ L +  + R D+G+Y I L+N+ G A ASI V
Sbjct: 8111 PTVSWHKDGKEV-KASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATASINV 8169

Query: 640  KVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLC 699
            KV+  P P      +++    C + WEPP +DGG+PIL Y +ER++     ++ +     
Sbjct: 8170 KVIGLPGPCKDIKASDITKSSCKLTWEPPEFDGGTPILHYVLERREAGRRTYIPVMSGEN 8229

Query: 700  KETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFV---PLAVTSPPTLLTVDSVTD 756
            K  ++  K +I    Y  R+ AVN +G  +      P +   P     PP  + V + T 
Sbjct: 8230 K-LSWTVKDLIPNGEYFFRVKAVNKVGGGEYIELKNPVIAQDPKQPPDPPVDVEVHNPTA 8288

Query: 757  TTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVR 816
              +T+ W+PP + G + + GY++E   +G E W   N+ L+    +T  GL    +   R
Sbjct: 8289 EAMTITWKPPLYDGGSKIMGYIIEKIAKGEERWKRCNEHLVPILTYTAKGLEEGKEYQFR 8348

Query: 817  VKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRP 876
            V+A NAAG SEP   + P    + I+ PK+ +   L+   ++R G+ + L     G P P
Sbjct: 8349 VRAENAAGISEPSRATPPTKAVDPIDAPKVILRTSLE---VKR-GDEIALDASISGSPYP 8404

Query: 877  ELTWKKD-----GAEIDK------------------------NQINIRNSET-DTIIFIR 906
             +TW KD       EI K                         +++I NS+  ++ + +R
Sbjct: 8405 TITWIKDENVIVPEEIKKRAAPLVRRRKGEVQEEEPFVLPLTQRLSIDNSKKGESQLRVR 8464

Query: 907  KAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDG 966
             + R   G Y ++V+ D  +  A   + ++D PGPP     ED+   +V   W PP DDG
Sbjct: 8465 DSLRPDHGLYMIKVENDHGIAKAPCTVSVLDTPGPPINFVFEDIRKTSVLCKWEPPLDDG 8524

Query: 967  NAAITGYTIQKAD--KKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCG 1019
             + I  YT++K D  K   EW  V         ++T+L+ G EY FRV +EN  G
Sbjct: 8525 GSEIINYTLEKKDKTKPDSEWIVVTSTLRHCKYSVTKLIEGKEYLFRVRAENRFG 8579



 Score =  220 bits (561), Expect = 5e-57
 Identities = 176/654 (26%), Positives = 292/654 (44%), Gaps = 63/654 (9%)

Query: 405   EIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPL 464
             +++ G K  +RIR +         GA  A +     +    +  A       P  +L P 
Sbjct: 14032 DLVEGGKYEFRIRAKNTA------GAISAPSESTETIICKDEYEA-------PTIVLDPT 14078

Query: 465   TDQ--TVNLGKEICLKCE--ISENIP-GKWTKNGLPVQESDRLKVVHKGRIHKLVIANAL 519
                  T+  G  I L     + + +P   W+K G  ++ SD  ++        L I  A 
Sbjct: 14079 IKDGLTIKAGDTIVLNAISILGKPLPKSSWSKAGKDIRPSDITQITSTPTSSMLTIKYAT 14138

Query: 520   TEDEGDY-VFAPDAYNVTLP-AKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGE 577
              +D G+Y + A + +   +   KV V+D P     G      ++ ++  K  L    +  
Sbjct: 14139 RKDAGEYTITATNPFGTKVEHVKVTVLDVP-----GPPGPVEISNVSAEKATL----TWT 14189

Query: 578   PPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLK----NE---- 629
             PP +   S     I+E           ++S L+  +   D     H+  K    NE    
Sbjct: 14190 PPLEDGGSPIKSYILEKR---------ETSRLLWTVVSEDIQSCRHVATKLIQGNEYIFR 14240

Query: 630   --------AGEAHASIKVKVVDF---PDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILG 678
                      GE   S  VK+VD    P PP  P V+ V  +   ++W+ P  DGGS I G
Sbjct: 14241 VSAVNHYGKGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSWKRPVDDGGSEITG 14300

Query: 679   YFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFV 738
             Y +ER++K+S RW+R       +   +   + EG  YE R+ A N  GI  PS  S   +
Sbjct: 14301 YHVERREKKSLRWVRAIKTPVSDLRCKVTGLQEGSTYEFRVSAENRAGIGPPSEASDSVL 14360

Query: 739   PLAVTSPPTLLTVDSVTDTT---VTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIV-ANK 794
                   PP   +   VTDTT    ++ W  P + G   + GYV+E+   G E WI     
Sbjct: 14361 MKDAAYPPGPPSNPHVTDTTKKSASLAWGKPHYDGGLEITGYVVEHQKVGDEAWIKDTTG 14420

Query: 795   DLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQ 854
               +  T+F +  L T  K   R+ A+N AG  EP       +V+  + P    +   L++
Sbjct: 14421 TALRITQFVVPDLQTKEKYNFRISAINDAGVGEPAVIPDVEIVEREMAPD-FELDAELRR 14479

Query: 855   TYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSG 914
             T + R G ++ + +P +G+P PE+TW KD   + KN+ NI N+E+ T++ I +  R  +G
Sbjct: 14480 TLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINL-KNRANIENTESFTLLIIPECNRYDTG 14538

Query: 915   KYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYT 974
             K+ + ++     ++  ++++++D PGP   ++  D+  ++V L W  P  DG + IT Y 
Sbjct: 14539 KFVMTIENPAGKKSGFVNVRVLDTPGPVLNLRPTDITKDSVTLHWDLPLIDGGSRITNYI 14598

Query: 975   IQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTK 1028
             ++K +     + T     H+ +  +T L  G EY+FRV +EN  G+ E    T+
Sbjct: 14599 VEKREATRKSYSTATTKCHKCTYKVTGLSEGCEYFFRVMAENEYGIGEPTETTE 14652



 Score =  218 bits (554), Expect = 3e-56
 Identities = 159/598 (26%), Positives = 266/598 (44%), Gaps = 55/598 (9%)

Query: 459   KILTPLTDQTVNLGKEICLKCEISENIPG----------KWTKNGLPVQESDRLKVVHKG 508
             K++ P  +  V L + + +K   +   P           KWT +G  ++  +   V    
Sbjct: 11199 KLVPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDN 11258

Query: 509   RIHKLVIANALTEDEGDYVFAPD--AYNVTLPAKVHVID---PPKIILDGLDADNTVTVI 563
                 L I N L  D G+Y       A + T+   + V+D   PP   ++ LD        
Sbjct: 11259 FSSVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTVLDVPGPPTGPINILDVTPE---- 11314

Query: 564   AGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIR-----TESYPDSSTLVIDIAERDD 618
                     + IS +PP     S     I+E     +       S    + L I   ++  
Sbjct: 11315 -------HMTISWQPPKDDGGSPVINYIVEKQDTRKDTWGVVSSGSSKTKLKIPHLQKGC 11367

Query: 619   SGVYHINLKNEAG-----EAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGG 673
               V+ +  +N+ G     ++  ++       P PP  P VT++ ++   ++W  P  DGG
Sbjct: 11368 EYVFRVRAENKIGVGPPLDSTPTVAKHKFSPPSPPGKPVVTDITENAATVSWTLPKSDGG 11427

Query: 674   SPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMP 733
             SPI GY++ER++  + +W+R+N     +  F    + EG  YE R+FA N  G+SKPS  
Sbjct: 11428 SPITGYYMERREV-TGKWVRVNKTPIADLKFRVTGLYEGNTYEFRVFAENLAGLSKPSPS 11486

Query: 734   SRPFV---PLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWI 790
             S P     P+    PP    +   +  T  + W  P   G + + GYV+E    GT  W 
Sbjct: 11487 SDPIKACRPIKPPGPPINPKLKDKSRETADLVWTKPLSDGGSPILGYVVECQKPGTAQWN 11546

Query: 791   VANKD-LIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIP 849
               NKD LI +  F + GL    +   R+KA N  G  EP+  ++ ++ K+I+ PP++ + 
Sbjct: 11547 RINKDELIRQCAFRVPGLIEGNEYRFRIKAANIVGEGEPRELAESVIAKDILHPPEVELD 11606

Query: 850   RHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTI------- 902
                +     RVG+ + ++   +G+P P++TW K+G      ++ +R    D I       
Sbjct: 11607 VTCRDVITVRVGQTIRILARVKGRPEPDITWTKEG------KVLVREKRVDLIQDLPRVE 11660

Query: 903   IFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPP 962
             + I++A R+  GKY +  K        S  + ++DRPGP Q +K+ +V  EN  ++W  P
Sbjct: 11661 LQIKEAVRADHGKYIISAKNSSGHAQGSAIVNVLDRPGPCQNLKVTNVTKENCTISWENP 11720

Query: 963   KDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGL 1020
              D+G + IT + ++        W  V     +       L+  NEYYFRV +EN  G+
Sbjct: 11721 LDNGGSEITNFIVEYRKPNQKGWSIVASDVTKRLIK-ANLLANNEYYFRVCAENKVGV 11777



 Score =  214 bits (544), Expect = 5e-55
 Identities = 128/407 (31%), Positives = 204/407 (50%), Gaps = 22/407 (5%)

Query: 636  SIKVKVVD---FPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWM 692
            S KV + D    P PP  P V        +++W PP  +GGSPI GY++E++++ S  W 
Sbjct: 9282 SDKVVIQDPYRLPGPPGKPKVLARTKGSMLVSWTPPLDNGGSPITGYWLEKREEGSPYWS 9341

Query: 693  RLNFDLC-----KETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFV---PLAVTS 744
            R++         K   F   +++EGV Y+ R  A+NA GI  PS PS P V   P+    
Sbjct: 9342 RVSRAPITKVGLKGVEFNVPRLLEGVKYQFRAMAINAAGIGPPSEPSDPEVAGDPIFPPG 9401

Query: 745  PPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKD--LIDKTKF 802
            PP+   V   T +++++ W+PP   G + + GY++E   EGT DW   N+   LI   + 
Sbjct: 9402 PPSCPEVKDKTKSSISLGWKPPAKDGGSPIKGYIVEMQEEGTTDWKRVNEPDKLITTCEC 9461

Query: 803  TITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGE 862
             +  L    K   RVKAVN AG SEP   +  I   +I E P++ I    +   + + G 
Sbjct: 9462 VVPNLKELRKYRFRVKAVNEAGESEPSDTTGEIPATDIQEEPEVFIDIGAQDCLVCKAGS 9521

Query: 863  AVNLVIPFQGKPRPELTWK---------KDGAEIDKNQINIRNSETDTIIFIRKAERSHS 913
             + +    +G+P P+ +W+         KDG         +  +E  ++I I + +RSH+
Sbjct: 9522 QIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECKRSHT 9581

Query: 914  GKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGY 973
            GKY +  K     +TA+  ++++D PGPP+ +K+ D+   +  L+W  P DDG   I GY
Sbjct: 9582 GKYSITAKNKAGQKTANCRVKVMDVPGPPKDLKVSDITRGSCRLSWKMPDDDGGDRIKGY 9641

Query: 974  TIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGL 1020
             I+K       W  V      T+  + +L+   +Y+FRV +EN  G+
Sbjct: 9642 VIEKRTIDGKAWTKVNPDCGSTTFVVPDLLSEQQYFFRVRAENRFGI 9688



 Score =  214 bits (544), Expect = 5e-55
 Identities = 163/595 (27%), Positives = 269/595 (45%), Gaps = 44/595 (7%)

Query: 468   TVNLGKEICLKCEISENIPGK--WTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGD 525
             T+  G ++ L   +      K  WTK    +   +++ + + G+    VI      D G 
Sbjct: 22753 TIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSGK 22812

Query: 526   YVFAPDAYNVT--LPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPP---- 579
             Y       + T  +   V V+D P     G     TV+ +   K  L   +  E      
Sbjct: 22813 YTLTVKNASGTKAVSVMVKVLDSP-----GPCGKLTVSRVTQEKCTLAWSLPQEDGGAEI 22867

Query: 580   -----PKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAG--- 631
                   +   SR +  I+EG     T SY      V+    +++  ++ +   N+ G   
Sbjct: 22868 THYIVERRETSRLNWVIVEGE--CPTLSY------VVTRLIKNNEYIFRVRAVNKYGPGV 22919

Query: 632   --EAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSS 689
               E+   +       P PP  P     G +  I+ W  P  DGG+ I  Y +++++K+S 
Sbjct: 22920 PVESEPIVARNSFTIPSPPGIPEEVGTGKEHIIIQWTKPESDGGNEISNYLVDKREKKSL 22979

Query: 690   RWMRLNFD-LCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFV----PLAVTS 744
             RW R+N D +  +T  +   ++EG  Y+ R+ AVNA G S+PS  S  F+    P     
Sbjct: 22980 RWTRVNKDYVVYDTRLKVTSLMEGCDYQFRVTAVNAAGNSEPSEASN-FISCREPSYTPG 23038

Query: 745   PPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWI-VANKDLIDKTKFT 803
             PP+   V   T  ++++ W  P + G   + GYVLE   + T+ W  V     I  T+FT
Sbjct: 23039 PPSAPRVVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDTDQWYRVHTNATIRNTEFT 23098

Query: 804   ITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEA 863
             +  L    K   RV AVN  G SE       I   E IE P + +   LK+T   R G +
Sbjct: 23099 VPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEIPDLELADDLKKTVTIRAGAS 23158

Query: 864   VNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVD 923
             + L++   G+P P +TW K G ++    I I  +E+ +++ + K  R  +GKY ++ +  
Sbjct: 23159 LRLMVSVSGRPPPVITWSKQGIDLASRAI-IDTTESYSLLIVDKVNRYDAGKYTIEAENQ 23217

Query: 924   KFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSM 983
                ++A++ +++ D PGP   VK+++V  ++V +TW  P  DG A +  Y ++K +    
Sbjct: 23218 SGKKSATVLVKVYDTPGPCPSVKVKEVSRDSVTITWEIPTIDGGAPVNNYIVEKREAAMR 23277

Query: 984   EWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSE-----DATMTKESAVI 1033
              + TV     +T   I+ LV G  YYFRV  EN+ G+ E     DA +  E  ++
Sbjct: 23278 AFKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYGIGEPCETSDAVLVSEVPLV 23332



 Score =  213 bits (543), Expect = 6e-55
 Identities = 156/581 (26%), Positives = 275/581 (47%), Gaps = 32/581 (5%)

Query: 469   VNLGKEICLKCEI-SENIPGK-WTKNGLPVQESD-RLKVVHKGRIHKLVIANALTEDEGD 525
             V+ G+   L+ +I  + IP   W+K+G  ++E+  R+++    +   LV+ + +  D G 
Sbjct: 18414 VHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQ 18473

Query: 526   YVFAPDAYNVT--LPAKVHVIDPP-----KIILDGLDAD------NTVTVIAGNKLRLEI 572
             Y+        T  +P  V V+D P      + + G+ A+      N      G  +   I
Sbjct: 18474 YILKLSNVGGTKSIPITVKVLDRPGPPEGPLKVTGVTAEKCYLAWNPPLQDGGANISHYI 18533

Query: 573   PISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGE 632
              I      +  W++    +   + ++ T+  P +  +   +A       Y I    E+G 
Sbjct: 18534 -IEKRETSRLSWTQVSTEVQALNYKV-TKLLPGNEYIFRVMAVNK----YGIGEPLESGP 18587

Query: 633   AHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWM 692
               A    K    P PP  P V+ +  D  ++ W  P  DGG+ I GY +E++ K+  RW 
Sbjct: 18588 VTACNPYKP---PGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDKEGVRWT 18644

Query: 693   RLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVD 752
             + N     +       + EG +YE R+ A NA G+ +PS PS  +       PP   +  
Sbjct: 18645 KCNKKTLTDLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRACDALYPPGPPSNP 18704

Query: 753   SVTDT---TVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDL-IDKTKFTITGLP 808
              VTDT   +V++ W  P + G A + GYV+E      ++W        +   +FT+T L 
Sbjct: 18705 KVTDTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAADEWTTCTPPTGLQGKQFTVTKLK 18764

Query: 809   TDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVI 868
              + +   R+ A+N+ G  EP      ++ +E IEPP+I +   L++  + R    + L +
Sbjct: 18765 ENTEYNFRICAINSEGVGEPATLPGSVVAQERIEPPEIELDADLRKVVVLRASATLRLFV 18824

Query: 869   PFQGKPRPELTWKK-DGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVE 927
               +G+P PE+ W+K +G   D+ QI + +S   T++ I    R  SG+Y+L ++ +   +
Sbjct: 18825 TIKGRPEPEVKWEKAEGILTDRAQIEVTSS--FTMLVIDNVTRFDSGRYNLTLENNSGSK 18882

Query: 928   TASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFT 987
             TA ++++++D P  P  + I +V  ++V L+W PP  DG A IT Y ++K +     + T
Sbjct: 18883 TAFVNVRVLDSPSAPVNLTIREVKKDSVTLSWEPPLIDGGAKITNYIVEKRETTRKAYAT 18942

Query: 988   VIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTK 1028
             +  +  +T+  I  L  G  YYFRV + N  G+   A  T+
Sbjct: 18943 ITNNCTKTTFRIENLQEGCSYYFRVLASNEYGIGLPAETTE 18983



 Score =  213 bits (542), Expect = 8e-55
 Identities = 117/390 (30%), Positives = 208/390 (53%), Gaps = 6/390 (1%)

Query: 645   PDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTF 704
             P PP  P VT++  +   + W  P  DGGS I GYF+E++ K+S  W ++  +  ++T  
Sbjct: 20761 PGPPGIPEVTKITKNSMTVVWSRPIADGGSDISGYFLEKRDKKSLGWFKVLKETIRDTRQ 20820

Query: 705   EPKKMIEGVAYEVRIFAVNAIG---ISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTM 761
             +   + E   Y+ R+ AVNA G    S+PS   +   P+    PP  + +   T +++T+
Sbjct: 20821 KVTGLTENSDYQYRVCAVNAAGQGPFSEPSEFYKAADPIDPPGPPAKIRIADSTKSSITL 20880

Query: 762   RWRPPDHIGAAGLDGYVLEYCFEGTEDWI-VANKDLIDKTKFTITGLPTDAKIFVRVKAV 820
              W  P + G + + GYV+E      E+W  V+ K  +  T++ ++ L      + RV AV
Sbjct: 20881 GWSKPVYDGGSAVTGYVVEIRQGEEEEWTTVSTKGEVRTTEYVVSNLKPGVNYYFRVSAV 20940

Query: 821   NAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTW 880
             N AG  EP   ++P+  K+I+E P+I +   L+ + I + GE V ++IPF+G+P P +TW
Sbjct: 20941 NCAGQGEPIEMNEPVQAKDILEAPEIDLDVALRTSVIAKAGEDVQVLIPFKGRPPPTVTW 21000

Query: 881   KKDGAEIDKN-QINIRNSETDTIIFIRKAERSHSGKYDLQVKVD-KFVETASIDIQIIDR 938
             +KD   +  + + +I N+++ +++ I +  R+ +GKY L ++      +++++ ++++D 
Sbjct: 21001 RKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKYILTIENGVGEPKSSTVSVKVLDT 21060

Query: 939   PGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSAT 998
             P   Q ++++ V    V L W PP  DG + I  Y I+K D     W  V      TS  
Sbjct: 21061 PAACQKLQVKHVSRGTVTLLWDPPLIDGGSPIINYVIEKRDATKRTWSVVSHKCSSTSFK 21120

Query: 999   ITELVIGNEYYFRVFSENMCGLSEDATMTK 1028
             + +L     ++FRV +EN  G+ E    T+
Sbjct: 21121 LIDLSEKTPFFFRVLAENEIGIGEPCETTE 21150



 Score =  210 bits (535), Expect = 5e-54
 Identities = 144/504 (28%), Positives = 232/504 (46%), Gaps = 21/504 (4%)

Query: 545  DPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYP 604
            +PP + LD +     + ++AG  LR+   ++G P P  +W++ +  +     R+  ++  
Sbjct: 8795 EPPAVELD-VSVKGGIQIMAGKTLRIPAVVTGRPVPTKVWTKEEGEL--DKDRVVIDNVG 8851

Query: 605  DSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMN 664
              S L+I  A R D G Y I   N  G   A+ +V+V D P P +           C++N
Sbjct: 8852 TKSELIIKDALRKDHGRYVITATNSCGSKFAAARVEVFDVPGPVLDLKPVVTNRKMCLLN 8911

Query: 665  WEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNA 724
            W  P  DGGS I G+ IERK  +   W R   +  + +  +   ++EG  Y+ R+ A N 
Sbjct: 8912 WSDPEDDGGSEITGFIIERKDAKMHTW-RQPIE-TERSKCDITGLLEGQEYKFRVIAKNK 8969

Query: 725  IGISKPSM--PSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYC 782
             G   P    P     PL   + P  LT    T +T+T+ W+ P   G + + GY++E  
Sbjct: 8970 FGCGPPVEIGPILAVDPLGPPTSPERLTYTERTKSTITLDWKEPRSNGGSPIQGYIIEKR 9029

Query: 783  FEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIE 842
                 D+   NK L   T F +  L        RVKAVN  G SEP      +++++   
Sbjct: 9030 RHDKPDFERVNKRLCPTTSFLVENLDEHQMYEFRVKAVNEIGESEPS-LPLNVVIQDDEV 9088

Query: 843  PPKIRIPRHLKQTYIR-RVGEAVNLVIPFQGKPRPELTWKKDGAEIDK-------NQINI 894
            PP I++   ++   I+ + GE V++     G P P++ W K+   I+K        +  +
Sbjct: 9089 PPTIKLRLSVRGDTIKVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEV 9148

Query: 895  RNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGEN 954
              SE  T + I KA R   G Y +           ++ +++ DRP PP+ + + D+  E+
Sbjct: 9149 SRSEAKTELSIPKAVREDKGTYTVTASNRLGSVFRNVHVEVYDRPSPPRNLAVTDIKAES 9208

Query: 955  VALTWTPPKDDGNAAITGYTIQKAD--KKSMEWFTVIEHYHRTSATITELVIGNEYYFRV 1012
              LTW  P D+G + IT Y I K D  +K  EW  V          I +L+   +Y FRV
Sbjct: 9209 CYLTWDAPLDNGGSEITHYVIDKRDASRKKAEWEEVTNTAVEKRYGIWKLIPNGQYEFRV 9268

Query: 1013 FSENMCGLSEDATMTKESAVIARD 1036
             + N  G+S++    K   V+ +D
Sbjct: 9269 RAVNKYGISDEC---KSDKVVIQD 9289



 Score =  209 bits (533), Expect = 9e-54
 Identities = 155/595 (26%), Positives = 276/595 (46%), Gaps = 28/595 (4%)

Query: 445   GQSSAKLSVDLKPLKILTPLTDQ-TVNLGKEICLKCEI-SENIPG-KWTKNGLPVQESDR 501
             G  +AK  V+L  + +     D   VN G+   L+ ++  + +P  +W +    ++ES R
Sbjct: 17307 GPITAKDEVELPRISMDPKFRDTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESAR 17366

Query: 502   LKVVHKGRIHKLVIANALTEDEGDYVFAPD--AYNVTLPAKVHVIDPPKIILDGLDADNT 559
              ++ +      L++ +A+  D G Y+      A + + P  V V+D P       +    
Sbjct: 17367 CEIKNTDFKALLIVKDAIRIDGGQYILRASNVAGSKSFPVNVKVLDRP----GPPEGPVQ 17422

Query: 560   VTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIR-----TESYPDSSTLVIDIA 614
             VT +   K  L    +  PP +   S     ++E     R       S   +++L +   
Sbjct: 17423 VTGVTSEKCSL----TWSPPLQDGGSDISHYVVEKRETSRLAWTVVASEVVTNSLKVTKL 17478

Query: 615   ERDDSGVYHINLKNE--AGEAHASIKVKVVD---FPDPPVAPTVTEVGDDWCIMNWEPPA 669
                +  V+ I   N+   GE   S  V + +    P PP +  VT +  D   + W  P 
Sbjct: 17479 LEGNEYVFRIMAVNKYGVGEPLESAPVLMKNPFVLPGPPKSLEVTNIAKDSMTVCWNRPD 17538

Query: 670   YDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISK 729
              DGGS I+GY +E++ +   RW++ N     +       + E   YE R+ A NA G+ +
Sbjct: 17539 SDGGSEIIGYIVEKRDRSGIRWIKCNKRRITDLRLRVTGLTEDHEYEFRVSAENAAGVGE 17598

Query: 730   PSMPS---RPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGT 786
             PS  +   +   P+    PPT   +   T  ++T+ W  P + G + + GYV+E C    
Sbjct: 17599 PSPATVYYKACDPVFKPGPPTNAHIVDTTKNSITLAWGKPIYDGGSEILGYVVEICKADE 17658

Query: 787   EDW-IVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPK 845
             E+W IV  +  +  T+F I+ L    +  +RV A+N  G  E       +  ++ +E P+
Sbjct: 17659 EEWQIVTPQTGLRVTRFEISKLTEHQEYKIRVCALNKVGLGEATSVPGTVKPEDKLEAPE 17718

Query: 846   IRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFI 905
             + +   L++  + R G +  + IPF+G+P PE+TW ++  E   +++ I      T + I
Sbjct: 17719 LDLDSELRKGIVVRAGGSARIHIPFKGRPTPEITWSREEGEFT-DKVQIEKGVNYTQLSI 17777

Query: 906   RKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDD 965
                +R+ +GKY L+++     ++A + ++++D PGPPQ + +++V  ++  L W PP  D
Sbjct: 17778 DNCDRNDAGKYILKLENSSGSKSAFVTVKVLDTPGPPQNLAVKEVRKDSAFLVWEPPIID 17837

Query: 966   GNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGL 1020
             G A +  Y I K +     +  V     +TS  +  L  G  YYFRV +EN  G+
Sbjct: 17838 GGAKVKNYVIDKRESTRKAYANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFGV 17892



 Score =  207 bits (528), Expect = 4e-53
 Identities = 124/404 (30%), Positives = 206/404 (50%), Gaps = 10/404 (2%)

Query: 645  PDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTF 704
            P PP A  V +V      + WEPP  DGG PI  Y IE+K++  +RW++       +  F
Sbjct: 7879 PGPPYALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKERLGTRWVKAGKTAGPDCNF 7938

Query: 705  EPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFV---PLAVTSPPTLLTVDSVTDTTVTM 761
                +IEG   + ++ A N  G+  PS P+       P +  SPP  L V       + +
Sbjct: 7939 RVTDVIEGTEVQFQVRAENEAGVGHPSEPTEILSIEDPTSPPSPPLDLHVTDAGRKHIAI 7998

Query: 762  RWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTIT-GLPTDAKIFVRVKAV 820
             W+PP+  G + + GY +E C  GTE W+  N   I   KF +  G+  D +  +RV+AV
Sbjct: 7999 AWKPPEKNGGSPIIGYHVEMCPVGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYVLRVRAV 8058

Query: 821  NAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTW 880
            NA G SEP   S+ ++ K+    P I +  H     I   GE +++ +PF+  P P ++W
Sbjct: 8059 NAIGVSEPSEISENVVAKDPDCKPTIDLETH---DIIVIEGEKLSIPVPFRAVPVPTVSW 8115

Query: 881  KKDGAEID-KNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRP 939
             KDG E+   +++ ++N      + + K+ R+ +G Y + ++      TASI++++I  P
Sbjct: 8116 HKDGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATASINVKVIGLP 8175

Query: 940  GPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATI 999
            GP + +K  D+   +  LTW PP+ DG   I  Y +++ +     +  V+   ++ S T+
Sbjct: 8176 GPCKDIKASDITKSSCKLTWEPPEFDGGTPILHYVLERREAGRRTYIPVMSGENKLSWTV 8235

Query: 1000 TELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNP 1043
             +L+   EY+FRV + N  G  E   +  ++ VIA+D K   +P
Sbjct: 8236 KDLIPNGEYFFRVKAVNKVGGGEYIEL--KNPVIAQDPKQPPDP 8277



 Score =  205 bits (522), Expect = 2e-52
 Identities = 140/501 (27%), Positives = 228/501 (45%), Gaps = 20/501 (3%)

Query: 543   VIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTES 602
             ++ PP++ LD +   + +TV  G  +R+   + G P P   W++  K ++      R + 
Sbjct: 11597 ILHPPEVELD-VTCRDVITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREK---RVDL 11652

Query: 603   YPDSSTLVIDIAE--RDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDW 660
               D   + + I E  R D G Y I+ KN +G A  S  V V+D P P     VT V  + 
Sbjct: 11653 IQDLPRVELQIKEAVRADHGKYIISAKNSSGHAQGSAIVNVLDRPGPCQNLKVTNVTKEN 11712

Query: 661   CIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIF 720
             C ++WE P  +GGS I  + +E +K     W  +  D+ K        ++    Y  R+ 
Sbjct: 11713 CTISWENPLDNGGSEITNFIVEYRKPNQKGWSIVASDVTKRLI--KANLLANNEYYFRVC 11770

Query: 721   AVNAIGISKPSMPSRPFV---PLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGY 777
             A N +G+        P +   P+     P  L +     T V ++WR PD+ G +    Y
Sbjct: 11771 AENKVGVGPTIETKTPILAINPIDRPGEPENLHIADKGKTFVYLKWRRPDYDGGSPNLSY 11830

Query: 778   VLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILV 837
              +E   +G++DW   +K  I +T + +     +     RV+  N  G S+    ++ ++V
Sbjct: 11831 HVERRLKGSDDWERVHKGSIKETHYMVDRCVENQIYEFRVQTKNEGGESD-WVKTEEVVV 11889

Query: 838   KEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQ---INI 894
             KE ++ P + +   L      + G+ + L    +GKP PE+ W KD    D  +   + I
Sbjct: 11890 KEDLQKPVLDLK--LSGVLTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKI 11947

Query: 895   RNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGEN 954
                   +   + KA+RS  GKY +          A   + ++D+PGP + +KI DV  + 
Sbjct: 11948 DTRADSSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATVNVLDKPGPVRNLKIVDVSSDR 12007

Query: 955   VALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFS 1014
               + W PP+DDG   I  Y ++K + K M W T          T+T L+ GNEY FRV +
Sbjct: 12008 CTVCWDPPEDDGGCEIQNYILEKCETKRMVWSTYSATVLTPGTTVTRLIEGNEYIFRVRA 12067

Query: 1015  ENMCGLSEDATMTKESAVIAR 1035
             EN  G       T+   VIA+
Sbjct: 12068 ENKIGTGPP---TESKPVIAK 12085



 Score =  204 bits (520), Expect = 3e-52
 Identities = 148/557 (26%), Positives = 258/557 (46%), Gaps = 31/557 (5%)

Query: 489   WTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAK----VHVI 544
             W K+G+ +++   +++        L + +A  +  G  V+  +A N +  AK    V V 
Sbjct: 21687 WFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRG--VYTVEAKNASGSAKAEIKVKVQ 21744

Query: 545   DPPKIILDGLDADNTVTVIAGNKLRL--EIPISGEPPP-------KAMWSRGDKAIMEGS 595
             D P  ++  +   N    I G K+ L  + P++    P       K   SR   A++E  
Sbjct: 21745 DTPGKVVGPIRFTN----ITGEKMTLWWDAPLNDGCAPITHYIIEKRETSRLAWALIED- 21799

Query: 596   GRIRTESYPDSSTLVIDIAERDDSGV--YHINLKNEAGEAHASIKVKVVDFPDPPVAPTV 653
              +   +SY     +  +  +   S V  + +    ++    A I+  V   PD P  P  
Sbjct: 21800 -KCEAQSYTAIKLINGNEYQFRVSAVNKFGVGRPLDSDPVVAQIQYTV---PDAPGIPEP 21855

Query: 654   TEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMR-LNFDLCKETTFEPKKMIEG 712
             + +  +   + W  P  DGGS I  Y +ER++K+S+RW++ ++     ET F+   + EG
Sbjct: 21856 SNITGNSITLTWARPESDGGSEIQQYILERREKKSTRWVKVISKRPISETRFKVTGLTEG 21915

Query: 713   VAYEVRIFAVNAIGISKPSMPSRPFV---PLAVTSPPTLLTVDSVTDTTVTMRWRPPDHI 769
               YE  + A NA G+   S  SR      P+    PPT++ V   + TTV++ W  P   
Sbjct: 21916 NEYEFHVMAENAAGVGPASGISRLIKCREPVNPPGPPTVVKVTDTSKTTVSLEWSKPVFD 21975

Query: 770   GAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPK 829
             G   + GY++E C     DW   N +   KT++T+T L    +   RV A+N AG  +  
Sbjct: 21976 GGMEIIGYIIEMCKADLGDWHKVNAEACVKTRYTVTDLQAGEEYKFRVSAINGAGKGDSC 22035

Query: 830   YYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDK 889
               +  I   + +  P++ I  + KQT++ R G ++ L I +QG+P P   W K  + +  
Sbjct: 22036 EVTGTIKAVDRLTAPELDIDANFKQTHVVRAGASIRLFIAYQGRPTPTAVWSKPDSNLSL 22095

Query: 890   NQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIED 949
              + +I  +++ + + +    R+ +GKY L V+ +   ++ +  ++++D PGPP  +  +D
Sbjct: 22096 -RADIHTTDSFSTLTVENCNRNDAGKYTLTVENNSGSKSITFTVKVLDTPGPPGPITFKD 22154

Query: 950   VWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYY 1009
             V   +  L W  P  DG A I  Y ++K +     W  + E   R    + +L  G  YY
Sbjct: 22155 VTRGSATLMWDAPLLDGGARIHHYVVEKREASRRSWQVISEKCTRQIFKVNDLAEGVPYY 22214

Query: 1010  FRVFSENMCGLSEDATM 1026
             FRV + N  G+ E   M
Sbjct: 22215 FRVSAVNEYGVGEPYEM 22231



 Score =  203 bits (517), Expect = 7e-52
 Identities = 137/482 (28%), Positives = 227/482 (47%), Gaps = 20/482 (4%)

Query: 645   PDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTF 704
             P  P  P V  V  +   + WE P +DGGS I+GY++E+K++ +  W++ N   C E  +
Sbjct: 22536 PSAPTRPEVYHVSANAMSIRWEEPYHDGGSKIIGYWVEKKERNTILWVKENKVPCLECNY 22595

Query: 705   EPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWR 764
             +   ++EG+ Y+ R +A+NA G+SK S  SRP +       P    V  VT +TV++ W 
Sbjct: 22596 KVTGLVEGLEYQFRTYALNAAGVSKASEASRPIMAQNPVDAPGRPEVTDVTRSTVSLIWS 22655

Query: 765   PPDHIGAAGLDGYVLE---YCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVN 821
              P + G + + GY++E       G   W+  N  ++    FT+T L        RV A N
Sbjct: 22656 APAYDGGSKVVGYIIERKPVSEVGDGRWLKCNYTIVSDNFFTVTALSEGDTYEFRVLAKN 22715

Query: 822   AAGA-SEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIR-RVGEAVNLVIPFQGKPRPELT 879
             AAG  S+    + P+  ++   PPK  +   L    +  R G  + L     GKP P++ 
Sbjct: 22716 AAGVISKGSESTGPVTCRDEYAPPKAELDARLHGDLVTIRAGSDLVLDAAVGGKPEPKII 22775

Query: 880   WKKDGAEIDK-NQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDR 938
             W K   E+D   +++++ +       I+  +RS SGKY L VK     +  S+ ++++D 
Sbjct: 22776 WTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSGKYTLTVKNASGTKAVSVMVKVLDS 22835

Query: 939   PGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSAT 998
             PGP   + +  V  E   L W+ P++DG A IT Y +++ +   + W  V       S  
Sbjct: 22836 PGPCGKLTVSRVTQEKCTLAWSLPQEDGGAEITHYIVERRETSRLNWVIVEGECPTLSYV 22895

Query: 999   ITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNP--VYEDFDFSEAPM- 1055
             +T L+  NEY FRV + N  G        +   ++AR+     +P  + E+    +  + 
Sbjct: 22896 VTRLIKNNEYIFRVRAVNKYG---PGVPVESEPIVARNSFTIPSPPGIPEEVGTGKEHII 22952

Query: 1056  --FTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMK-NKVAIVDDPRYRMFSNQGVCTLE 1112
               +T+P  +     G N   N  V    K  + W + NK  +V D R ++ S    C  +
Sbjct: 22953 IQWTKPESD-----GGNEISNYLVDKREKKSLRWTRVNKDYVVYDTRLKVTSLMEGCDYQ 23007

Query: 1113  IR 1114
              R
Sbjct: 23008 FR 23009



 Score =  200 bits (509), Expect = 6e-51
 Identities = 218/906 (24%), Positives = 364/906 (40%), Gaps = 113/906 (12%)

Query: 288  QVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEY 347
            +V +   V F  E+     + KW++N + I  S+KYI   K     L I +  + D + Y
Sbjct: 6345 RVKEQQEVVFNCEVNTEGAKAKWFRNEEAIFDSSKYIILQKDLVYTLRIRDAHLDDQANY 6404

Query: 348  YVTAGDE-----KCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKN 402
             V+  +      K +  L V E  + + + L+D      + V   C+V+  +  +KW KN
Sbjct: 6405 NVSLTNHRGENVKSAANLIVEEEDLRIVEPLKDIETMEKKSVTFWCKVNRLNVTLKWTKN 6464

Query: 403  GEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILT 462
            GEE+    +  YR  V+  KH+L I+     D  EY V     +S A+L +   P + + 
Sbjct: 6465 GEEVPFDNRVSYR--VDKYKHMLTIKDCGFPDEGEYIVTAGQDKSVAELLIIEAPTEFVE 6522

Query: 463  PLTDQTVNLGKEICLKCEIS-ENIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTE 521
             L DQTV    +    C++S E    KW +NG  ++E  + K    G IH+L+I +   +
Sbjct: 6523 HLEDQTVTEFDDAVFSCQLSREKANVKWYRNGREIKEGKKYKFEKDGSIHRLIIKDCRLD 6582

Query: 522  DEGDYVFAPD-----AYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISG 576
            DE +Y    +     A        V +I PP+ IL+   AD  V +   NK ++E+    
Sbjct: 6583 DECEYACGVEDRKSRARLFVEEIPVEIIRPPQDILEAPGAD-VVFLAELNKDKVEV---- 6637

Query: 577  EPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHAS 636
                   W R +  +++G               + DI  RD  G Y    K++  EA A 
Sbjct: 6638 ------QWLRNNMVVVQGDKHQMMSEGKIHRLQICDIKPRDQ-GEYRFIAKDK--EARAK 6688

Query: 637  IKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYF-IERKKKQSSRWMRLN 695
            +++          AP +     D  +        D G P+      +   K  + W + N
Sbjct: 6689 LELAA--------APKIKTADQDLVV--------DVGKPLTMVVPYDAYPKAEAEWFKEN 6732

Query: 696  FDL--------CKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPT 747
              L         ++T+F   +  +G     +I   N  G ++  +  +    + V  P  
Sbjct: 6733 EPLSTKTIDTTAEQTSFRILEAKKGDKGRYKIVLQNKHGKAEGFINLKV---IDVPGPVR 6789

Query: 748  LLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGL 807
             L V    D  V++ W  P   G + + GYV+E      + W++A  D  +  +FT+TGL
Sbjct: 6790 NLEVTETFDGEVSLAWEEPLTDGGSKIIGYVVERRDIKRKTWVLAT-DRAESCEFTVTGL 6848

Query: 808  PTDAKIFV-RVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNL 866
                  ++ RV A N  G  EP     P+  +   + P                G  +N+
Sbjct: 6849 QKGGVEYLFRVSARNRVGTGEPVETDNPVEARSKYDVP----------------GPPLNV 6892

Query: 867  VIPFQGKPRPELTWKKD----GAEIDKNQINIRNSET---DTIIFIRKAERS-------H 912
             I    +    LTW+      GAEI    I +R+  +   DT + +R  + S        
Sbjct: 6893 TITDVNRFGVSLTWEPPEYDGGAEITNYVIELRDKTSIRWDTAMTVRAEDLSATVTDVVE 6952

Query: 913  SGKYDLQVKVDKFV-----ETASIDIQI---IDRPGPPQIVKIEDVWGENVALTWTPPKD 964
              +Y  +V+    +       A+  +++   I+RP PP  +   D    +V L W PP  
Sbjct: 6953 GQEYSFRVRAQNRIGVGKPSAATPFVKVADPIERPSPPVNLTSSDQTQSSVQLKWEPPLK 7012

Query: 965  DGNAAITGYTIQKADKKSMEWFTV-IEHYHRTSATITELVIGNEYYFRVFSENMCGLSED 1023
            DG + I GY I++ ++    W    ++     +  +T L  GN+Y +RV +EN  G+S+ 
Sbjct: 7013 DGGSPILGYIIERCEEGKDNWIRCNMKLVPELTYKVTGLEKGNKYLYRVSAENKAGVSDP 7072

Query: 1024 ATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNA-TLNCSVRGNPK 1082
            + +                P+  D  F E  M      +   +   N  T+     G P+
Sbjct: 7073 SEIL--------------GPLTADDAFVEPTMDLSAFKDGLEVIVPNPITILVPSTGYPR 7118

Query: 1083 PKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLE 1142
            P  TW      +    R +M +      L I      D G Y  K  N + T+  E  ++
Sbjct: 7119 PTATWCFGDKVLETGDRVKMKTLSAYAELVISPSERSDKGIYTLKLENRVKTISGE--ID 7176

Query: 1143 VKVIAQ 1148
            V VIA+
Sbjct: 7177 VNVIAR 7182



 Score =  198 bits (503), Expect = 3e-50
 Identities = 173/674 (25%), Positives = 288/674 (42%), Gaps = 74/674 (10%)

Query: 398  KWFKNGEEIIP-----------GPKSRYRIRVEGKKHILIIEGATKA-------DAAEYS 439
            +W +  E ++P           G + ++R+R E    I     AT         DA +  
Sbjct: 8320 RWKRCNEHLVPILTYTAKGLEEGKEYQFRVRAENAAGISEPSRATPPTKAVDPIDAPKVI 8379

Query: 440  VMTT-----GGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKC---------EISENI 485
            + T+     G + +   S+   P   +T + D+ V + +EI  +          E+ E  
Sbjct: 8380 LRTSLEVKRGDEIALDASISGSPYPTITWIKDENVIVPEEIKKRAAPLVRRRKGEVQEEE 8439

Query: 486  PGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYN--VTLPAKVHV 543
            P       LP+ +   +    KG   +L + ++L  D G Y+   +  +     P  V V
Sbjct: 8440 PFV-----LPLTQRLSIDNSKKGE-SQLRVRDSLRPDHGLYMIKVENDHGIAKAPCTVSV 8493

Query: 544  IDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESY 603
            +D P   ++ +  D   T +             EPP       G   I+  +   + ++ 
Sbjct: 8494 LDTPGPPINFVFEDIRKTSVL---------CKWEPP----LDDGGSEIINYTLEKKDKTK 8540

Query: 604  PDSSTLVIDIAERD-----------DSGVYHINLKNEAGEAHASIKVKVVDF-----PDP 647
            PDS  +V+    R               ++ +  +N  G     +   +V       PD 
Sbjct: 8541 PDSEWIVVTSTLRHCKYSVTKLIEGKEYLFRVRAENRFGPGPPCVSKPLVAKDPFGPPDA 8600

Query: 648  PVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPK 707
            P  P V +V  +  ++ W  P  D GSPILGY++E+++  S+ W R+N  L         
Sbjct: 8601 PDKPIVEDVTSNSMLVKWNEPK-DNGSPILGYWLEKREVNSTHWSRVNKSLLNALKANVD 8659

Query: 708  KMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSP--PTLLTVDSVTDTTVTMRWRP 765
             ++EG+ Y  R+ A NA G  K S PS P       SP  P +  V   + TT+ + W P
Sbjct: 8660 GLLEGLTYVFRVCAENAAGPGKFSPPSDPKTAHDPISPPGPPIPRVTDTSSTTIELEWEP 8719

Query: 766  PDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGA 825
            P   G   + GY ++    GT +W    + +I   ++T+  +   A   +RV AVNAAG 
Sbjct: 8720 PAFNGGGEIVGYFVDKQLVGTNEWSRCTEKMIKVRQYTVKEIREGADYKLRVSAVNAAGE 8779

Query: 826  SEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGA 885
              P   +QP+ V E  EPP + +   +K       G+ + +     G+P P   W K+  
Sbjct: 8780 GPPG-ETQPVTVAEPQEPPAVELDVSVKGGIQIMAGKTLRIPAVVTGRPVPTKVWTKEEG 8838

Query: 886  EIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIV 945
            E+DK+++ I N  T + + I+ A R   G+Y +        + A+  +++ D PGP   +
Sbjct: 8839 ELDKDRVVIDNVGTKSELIIKDALRKDHGRYVITATNSCGSKFAAARVEVFDVPGPVLDL 8898

Query: 946  KIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIG 1005
            K      +   L W+ P+DDG + ITG+ I++ D K   W   IE   R+   IT L+ G
Sbjct: 8899 KPVVTNRKMCLLNWSDPEDDGGSEITGFIIERKDAKMHTWRQPIE-TERSKCDITGLLEG 8957

Query: 1006 NEYYFRVFSENMCG 1019
             EY FRV ++N  G
Sbjct: 8958 QEYKFRVIAKNKFG 8971



 Score =  192 bits (487), Expect = 2e-48
 Identities = 179/703 (25%), Positives = 312/703 (44%), Gaps = 63/703 (8%)

Query: 369   VTKQLEDTTAYCGERVELECE-VSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILII 427
             + K+++D T   GE  +L C+ V     ++KW++ G+E+I   K  Y++  +G+ H L +
Sbjct: 24230 IRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRK--YKMSSDGRTHTLTV 24287

Query: 428   EGATKADAAEYSVMTTGG----QSSAKLSVDLKP-LKILTPLTDQTVN-LGKEICLKCE- 480
                 + D   Y+ + T      ++S+KL +   P      PL ++    +G  + L    
Sbjct: 24288 MTEEQEDEGVYTCIATNEVGEVETSSKLLLQATPQFHPGYPLKEKYYGAVGSTLRLHVMY 24347

Query: 481   ISENIPGK-WTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPA 539
             I   +P   W      +Q S+ + + +      LV+ N   +           Y V L  
Sbjct: 24348 IGRPVPAMTWFHGQKLLQNSENITIENTEHYTHLVMKNVQRKTHAG------KYKVQLSN 24401

Query: 540   KVHVIDPPKIILDGLDADN----TVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIME-- 593
                 +D    ILD    D     T  ++    L+    IS +PP     S     ++E  
Sbjct: 24402 VFGTVDA---ILDVEIQDKPDKPTGPIVIEALLKNSAVISWKPPADDGGSWITNYVVEKC 24458

Query: 594   -----GSGRIRTESYPDSSTLVIDIAERDDSGVY-HINLKNEAG-----EAHASIKVKV- 641
                     ++ + +   ++  ++++ E  ++G Y  ++ +N  G     E  + + +K  
Sbjct: 24459 EAKEGAEWQLVSSAISVTTCRIVNLTE--NAGYYFRVSAQNTFGISDPLEVSSVVIIKSP 24516

Query: 642   VDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKE 701
              + P  P  PT+T V  D C++ W+PPA DGG+ I  Y++E+++K+ ++W+ +  +  +E
Sbjct: 24517 FEKPGAPGKPTITAVTKDSCVVAWKPPASDGGAKIRNYYLEKREKKQNKWISVTTEEIRE 24576

Query: 702   TTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTM 761
             T F  K +IEG+ YE R+   N  G S+ S  S P  P +          + + +  V  
Sbjct: 24577 TVFSVKNLIEGLEYEFRVKCENLGGESEWSEISEPITPKSDVPIQAPHFKEELRNLNVRY 24636

Query: 762   RWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTK-----FTITGLPTDAKIFVR 816
             +          G    ++++  +G E      K  I + K       I  +  D     +
Sbjct: 24637 QSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQLIIASVTDDDATVYQ 24696

Query: 817   VKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRV--GEAVNLVIPFQGKP 874
             V+A N  G+             E+  P KI +P+ L+         GE V++ IPF GKP
Sbjct: 24697 VRATNQGGSVSGT------ASLEVEVPAKIHLPKTLEGMGAVHALRGEVVSIKIPFSGKP 24750

Query: 875   RPELTWKKDGAEIDKN---QINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASI 931
              P +TW+K    ID N   Q+ +  S T +++F    ER  +G Y +  K    ++  ++
Sbjct: 24751 DPVITWQKGQDLIDNNGHYQVIVTRSFT-SLVFPNGVERKDAGFYVVCAKNRFGIDQKTV 24809

Query: 932   DIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEH 991
             ++ + D P PP+ VK+ DV  ++V LTWT P  DG + IT Y ++K    +  W  V   
Sbjct: 24810 ELDVADVPDPPRGVKVSDVSRDSVNLTWTEPASDGGSKITNYIVEKCATTAERWLRV-GQ 24868

Query: 992   YHRTSATITELVIGNEYYFRVFSENMCGLSE-----DATMTKE 1029
                T  T+  L     Y FRV +EN  GLS+     + T+TKE
Sbjct: 24869 ARETRYTVINLFGKTSYQFRVIAENKFGLSKPSEPSEPTITKE 24911



 Score =  181 bits (460), Expect = 3e-45
 Identities = 166/686 (24%), Positives = 284/686 (41%), Gaps = 75/686 (10%)

Query: 375  DTTAYCGERV-ELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKA 433
            D    CGE V E + EV+  +   KW+             YR++   +      +GA+K 
Sbjct: 7327 DKWVACGEPVAETKMEVTGLEEG-KWYA------------YRVKALNR------QGASKP 7367

Query: 434  DAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCEISENIPGK--WTK 491
                  +     Q + ++ +D+K L  LT      V  G +I L   ++     K  WTK
Sbjct: 7368 SRPTEEIQAVDTQEAPEIFLDVKLLAGLT------VKAGTKIELPATVTGKPEPKITWTK 7421

Query: 492  NGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNV----TLPAKVHVIDP- 546
              + +++  R+ + +  +   + I ++   D G Y+   +A NV    T   +V+V+D  
Sbjct: 7422 ADMILKQDKRITIENVPKKSTVTIVDSKRSDTGTYII--EAVNVCGRATAVVEVNVLDKP 7479

Query: 547  -PKIILDGLDADNTVTVIAGNKLR-------LEIPISGEPPPKAMWSRGDKAIMEGSGRI 598
             P    D  D  N   ++  N  R           +        +W +    + + + + 
Sbjct: 7480 GPPAAFDITDVTNESCLLTWNPPRDDGGSKITNYVVERRATDSEVWHKLSSTVKDTNFK- 7538

Query: 599  RTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGD 658
             T+  P+   +    AE     +Y +    +A    A  +    D P PP     +++  
Sbjct: 7539 ATKLIPNKEYIFRVAAE----NMYGVGEPVQASPITAKYQ---FDPPGPPTRLEPSDITK 7591

Query: 659  DWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVR 718
            D   + W  P  DGGSPI GY++ER    + +W+R N    K+TT+  K +     Y  R
Sbjct: 7592 DAVTLTWCEPDDDGGSPITGYWVERLDPDTDKWVRCNKMPVKDTTYRVKGLTNKKKYRFR 7651

Query: 719  IFAVNAIGISKPSMPSRPFV---PLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLD 775
            + A N  G  KPS  + P +   P+    PP   TV  V  T+V + W  P+H G A ++
Sbjct: 7652 VLAENLAGPGKPSKSTEPILIKDPIDPPWPPGKPTVKDVGKTSVRLNWTKPEHDGGAKIE 7711

Query: 776  GYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPI 835
             YV+E    GT++W+   +  +  T+  + GL    +   RV+AVN AG SEP   S P+
Sbjct: 7712 SYVIEMLKTGTDEWVRVAEG-VPTTQHLLPGLMEGQEYSFRVRAVNKAGESEPSEPSDPV 7770

Query: 836  LVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRP------------ELTWKKD 883
            L +E + PP    PR L+   I +    +   +P +    P               W+  
Sbjct: 7771 LCREKLYPPS--PPRWLEVINITKNTADLKWTVPEKDGGSPITNYIVEKRDVRRKGWQTV 7828

Query: 884  GAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQ 943
               +   +  +      ++   R A  +  G+ D        +E + +       PGPP 
Sbjct: 7829 DTTVKDTKCTVTPLTEGSLYVFRVAAENAIGQSDYTE-----IEDSVLAKDTFTTPGPPY 7883

Query: 944  IVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHY-HRTSATITEL 1002
             + + DV   +V L W PPK+DG   I  Y I+K ++    W    +      +  +T++
Sbjct: 7884 ALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKERLGTRWVKAGKTAGPDCNFRVTDV 7943

Query: 1003 VIGNEYYFRVFSENMCGLSEDATMTK 1028
            + G E  F+V +EN  G+   +  T+
Sbjct: 7944 IEGTEVQFQVRAENEAGVGHPSEPTE 7969



 Score =  162 bits (411), Expect = 1e-39
 Identities = 110/364 (30%), Positives = 175/364 (48%), Gaps = 16/364 (4%)

Query: 289  VDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYY 348
            V  G    F  EL+   + V+WY  G+++ PS K +   +G    L + + ++ D  E  
Sbjct: 5902 VTAGETATFDCELSYEDIPVEWYLKGKKLEPSDKVVPRSEGKVHTLTLRDVKLEDAGEVQ 5961

Query: 349  VTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIP 408
            +TA D K    LFV+EPP+  TK LED T   G    LECEVS ++A VKWFKNG EI+ 
Sbjct: 5962 LTAKDFKTHANLFVKEPPVEFTKPLEDQTVEEGATAVLECEVSRENAKVKWFKNGTEILK 6021

Query: 409  GPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQT 468
              K  Y I  +G+   L+I   T  D   Y+      ++S  L+V    ++ L PLTD  
Sbjct: 6022 SKK--YEIVADGRVRKLVIHDCTPEDIKTYTCDAKDFKTSCNLNVVPPHVEFLRPLTDLQ 6079

Query: 469  VNLGKEICLKCEIS-ENIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYV 527
            V   +    +CE+S EN   KW K+G  +++  +  ++ KG +  LVI   L +DE +Y 
Sbjct: 6080 VREKEMARFECELSRENAKVKWFKDGAEIKKGKKYDIISKGAVRILVINKCLLDDEAEY- 6138

Query: 528  FAPDAYNVTLPAKVHVIDPPKII---LDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMW 584
             + +         + V++   +    L  ++   T T+    KL  E+    +P  + +W
Sbjct: 6139 -SCEVRTARTSGMLTVLEEEAVFTKNLANIEVSETDTI----KLVCEV---SKPGAEVIW 6190

Query: 585  SRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDF 644
             +GD+ I+E +GR    +      LVI  A  +D+G Y+  L +   +    +     +F
Sbjct: 6191 YKGDEEIIE-TGRYEILTEGRKRILVIQNAHLEDAGNYNCRLPSSRTDGKVKVHELAAEF 6249

Query: 645  PDPP 648
               P
Sbjct: 6250 ISKP 6253



 Score =  157 bits (398), Expect = 4e-38
 Identities = 105/308 (34%), Positives = 159/308 (51%), Gaps = 19/308 (6%)

Query: 544   IDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESY 603
             +DPP+I +D    D T+ V AG   +++  I G+P P   W +GD+ +   + R+  +S 
Sbjct: 16233 VDPPRISMDPKYKD-TIVVHAGESFKVDADIYGKPIPTIQWIKGDQEL-SNTARLEIKST 16290

Query: 604   PDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTV-TEVGDDWCI 662
               +++L +  A R DSG Y +  KN AGE   ++ VKV+D P PP  P V + V  + C 
Sbjct: 16291 DFATSLSVKDAVRVDSGNYILKAKNVAGERSVTVNVKVLDRPGPPEGPVVISGVTAEKCT 16350

Query: 663   MNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDL----CKETTFEPKKMIEGVAYEVR 718
             + W+PP  DGGS I+ Y +ER++     W  ++ ++    CK T     K++EG  Y  R
Sbjct: 16351 LAWKPPLQDGGSDIINYIVERRETSRLVWTVVDANVQTLSCKVT-----KLLEGNEYTFR 16405

Query: 719   IFAVNAIGISKPSMPSRPFV---PLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLD 775
             I AVN  G+ +P + S P V   P  V   P    V +VT  ++ + W  P   G + + 
Sbjct: 16406 IMAVNKYGVGEP-LESEPVVAKNPFVVPDAPKAPEVTTVTKDSMIVVWERPASDGGSEIL 16464

Query: 776   GYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPI 835
             GYVLE   +    W   +K LI + +  +TGL  +     RV A NAAG SEP   S P 
Sbjct: 16465 GYVLEKRDKEGIRWTRCHKRLIGELRLRVTGLIENHDYEFRVSAENAAGLSEP---SPPS 16521

Query: 836   LVKEIIEP 843
               ++  +P
Sbjct: 16522 AYQKACDP 16529



 Score =  157 bits (398), Expect = 4e-38
 Identities = 101/319 (31%), Positives = 164/319 (51%), Gaps = 7/319 (2%)

Query: 531   DAYNVTLPAKV-HVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDK 589
             D   + LP  +   ++PP+I +    + +TV V AG+ L+++IPISG+P PK   SR D 
Sbjct: 20152 DPRELLLPVLIKEQLEPPEIDMKNFPS-HTVYVRAGSNLKVDIPISGKPLPKVTLSR-DG 20209

Query: 590   AIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPV 649
               ++ + R  TE   ++ T+ +  +   D+G Y I   N +G   A I + V+D P PP 
Sbjct: 20210 VPLKATMRFNTEITAENLTINLKESVTADAGRYEITAANSSGTTKAFINIVVLDRPGPPT 20269

Query: 650   APTV-TEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKK 708
              P V +++ ++   + WEPP YDGGS +  Y + +++  ++ W  ++  + + T  +  K
Sbjct: 20270 GPVVISDITEESVTLKWEPPKYDGGSQVTNYILLKRETSTAVWTEVSATVAR-TMMKVMK 20328

Query: 709   MIEGVAYEVRIFAVNAIGISK--PSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPP 766
             +  G  Y+ RI A N  GIS    S      +P     PP+   V +VT  ++T+ W  P
Sbjct: 20329 LTTGEEYQFRIKAENRFGISDHIDSACVTVKLPYTTPGPPSTPWVTNVTRESITVGWHEP 20388

Query: 767   DHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGAS 826
                G + + GY LE     +  W  ANK +I  T F +T +        RV A NAAG  
Sbjct: 20389 VSNGGSAVVGYHLEMKDRNSILWQKANKLVIRTTHFKVTTISAGLIYEFRVYAENAAGVG 20448

Query: 827   EPKYYSQPILVKEIIEPPK 845
             +P + S+P+L  +  EPP+
Sbjct: 20449 KPSHPSEPVLAIDACEPPR 20467



 Score =  157 bits (397), Expect = 5e-38
 Identities = 212/890 (23%), Positives = 342/890 (38%), Gaps = 93/890 (10%)

Query: 292  GGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTA 351
            G  V F+ EL   K+EV+W +N   +    K+    +G    L I + +  D  EY   A
Sbjct: 6621 GADVVFLAELNKDKVEVQWLRNNMVVVQGDKHQMMSEGKIHRLQICDIKPRDQGEYRFIA 6680

Query: 352  GDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSE-DDANVKWFKNGEEIIPGP 410
             D++   +L +   P + T   +D     G+ + +         A  +WFK  E     P
Sbjct: 6681 KDKEARAKLELAAAPKIKTAD-QDLVVDVGKPLTMVVPYDAYPKAEAEWFKENE-----P 6734

Query: 411  KSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLT--DQT 468
             S   I    ++    I  A K D   Y ++       A+  ++LK + +  P+   + T
Sbjct: 6735 LSTKTIDTTAEQTSFRILEAKKGDKGRYKIVLQNKHGKAEGFINLKVIDVPGPVRNLEVT 6794

Query: 469  VNLGKEICLKCEISENIPGKWTKN-GLPVQESD---RLKVVHKGRIHKLVIA-NALTEDE 523
                 E+ L  E  E +    +K  G  V+  D   +  V+   R          L +  
Sbjct: 6795 ETFDGEVSLAWE--EPLTDGGSKIIGYVVERRDIKRKTWVLATDRAESCEFTVTGLQKGG 6852

Query: 524  GDYVFAPDAYNVTLPAKVHVIDPP-----KIILDGLDADNTVTVIAGNKLRLEIPISGEP 578
             +Y+F   A N     +    D P     K  + G   + T+T +     R  + ++ EP
Sbjct: 6853 VEYLFRVSARNRVGTGEPVETDNPVEARSKYDVPGPPLNVTITDVN----RFGVSLTWEP 6908

Query: 579  PPKAMWSRGDKAIMEGSGRIR-------TESYPDSSTLVIDIAERDDSGVYHINLKNEAG 631
            P     +     ++E   +         T    D S  V D+ E  +   + +  +N  G
Sbjct: 6909 PEYDGGAEITNYVIELRDKTSIRWDTAMTVRAEDLSATVTDVVEGQEYS-FRVRAQNRIG 6967

Query: 632  EAHASIK---VKVVD---FPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKK 685
                S     VKV D    P PPV  T ++       + WEPP  DGGSPILGY IER +
Sbjct: 6968 VGKPSAATPFVKVADPIERPSPPVNLTSSDQTQSSVQLKWEPPLKDGGSPILGYIIERCE 7027

Query: 686  KQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGIS----------------K 729
            +    W+R N  L  E T++   + +G  Y  R+ A N  G+S                +
Sbjct: 7028 EGKDNWIRCNMKLVPELTYKVTGLEKGNKYLYRVSAENKAGVSDPSEILGPLTADDAFVE 7087

Query: 730  PSMPSRPF---VPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGT 786
            P+M    F   + + V +P T+L V S      T  W   D +   G    V        
Sbjct: 7088 PTMDLSAFKDGLEVIVPNPITIL-VPSTGYPRPTATWCFGDKVLETG--DRVKMKTLSAY 7144

Query: 787  EDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKI 846
             + +++  +  DK  +T+       K+  RVK ++  G  +    ++P   KE+      
Sbjct: 7145 AELVISPSERSDKGIYTL-------KLENRVKTIS--GEIDVNVIARPSAPKELKFGDIT 7195

Query: 847  RIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIR 906
            +   HL        G +       + +     TW K    +   +  + +         +
Sbjct: 7196 KDSVHLTWEPPDDDGGSPLTGYVVEKREVSRKTWTKVMDFVTDLEFTVPDLVQGKEYLFK 7255

Query: 907  KAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDG 966
               R+  G  +    VD+ V  ++        P PP+ VK  D    ++ LTW PPK+DG
Sbjct: 7256 VCARNKCGPGE-PAYVDEPVNMSTPATV----PDPPENVKWRDRTANSIFLTWDPPKNDG 7310

Query: 967  NAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATM 1026
             + I GY +++  + S +W    E    T   +T L  G  Y +RV + N  G S+ +  
Sbjct: 7311 GSRIKGYIVERCPRGSDKWVACGEPVAETKMEVTGLEEGKWYAYRVKALNRQGASKPSRP 7370

Query: 1027 TKESAVIARDGKIYKNPVYEDFDFSEAP---MFTQPLVNTYAIAGYNATLNCSVRGNPKP 1083
            T+E   +               D  EAP   +  + L      AG    L  +V G P+P
Sbjct: 7371 TEEIQAV---------------DTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEP 7415

Query: 1084 KITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLG 1133
            KITW K  + +  D R  + +     T+ I      D GTY  +AVN  G
Sbjct: 7416 KITWTKADMILKQDKRITIENVPKKSTVTIVDSKRSDTGTYIIEAVNVCG 7465



 Score =  157 bits (397), Expect = 5e-38
 Identities = 146/550 (26%), Positives = 232/550 (42%), Gaps = 42/550 (7%)

Query: 385   ELEC-EVSEDDANVKWFK----NGEEII-----------PGPKSRYRIRVEGKKHILIIE 428
             ELE   +S+D   ++W K     G+EI+              K   + R++ K+    I 
Sbjct: 24131 ELEILSISKDSVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERIKDKQ--FTIG 24188

Query: 429   GATKADAAEYSVMT---TGGQSSAKLSVDLKPLK-------ILTPLTDQTVNLGKEICLK 478
             G  +A   E+ V     TG     + ++ +K          I   + D T  LG+   L 
Sbjct: 24189 GLLEATEYEFRVFAENETGLSRPRRTAMSIKTKLTSGEAPGIRKEMKDVTTKLGEAAQLS 24248

Query: 479   CEI-SENIPG-KWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDY--VFAPDAYN 534
             C+I    +P  KW + G  + +S + K+   GR H L +     EDEG Y  +   +   
Sbjct: 24249 CQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVGE 24308

Query: 535   VTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEG 594
             V   +K+ +   P+    G           G+ LRL +   G P P   W  G K +++ 
Sbjct: 24309 VETSSKLLLQATPQFH-PGYPLKEKYYGAVGSTLRLHVMYIGRPVPAMTWFHGQK-LLQN 24366

Query: 595   SGRIRTESYPDSSTLVI-DIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTV 653
             S  I  E+    + LV+ ++  +  +G Y + L N  G   A + V++ D PD P  P V
Sbjct: 24367 SENITIENTEHYTHLVMKNVQRKTHAGKYKVQLSNVFGTVDAILDVEIQDKPDKPTGPIV 24426

Query: 654   TE-VGDDWCIMNWEPPAYDGGSPILGYFIER-KKKQSSRWMRLNFDLCKETTFEPKKMIE 711
              E +  +  +++W+PPA DGGS I  Y +E+ + K+ + W  ++  +   TT     + E
Sbjct: 24427 IEALLKNSAVISWKPPADDGGSWITNYVVEKCEAKEGAEWQLVSSAI-SVTTCRIVNLTE 24485

Query: 712   GVAYEVRIFAVNAIGISKPSMPSRPFV---PLAVTSPPTLLTVDSVTDTTVTMRWRPPDH 768
                Y  R+ A N  GIS P   S   +   P      P   T+ +VT  +  + W+PP  
Sbjct: 24486 NAGYYFRVSAQNTFGISDPLEVSSVVIIKSPFEKPGAPGKPTITAVTKDSCVVAWKPPAS 24545

Query: 769   IGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEP 828
              G A +  Y LE   +    WI    + I +T F++  L    +   RVK  N  G SE 
Sbjct: 24546 DGGAKIRNYYLEKREKKQNKWISVTTEEIRETVFSVKNLIEGLEYEFRVKCENLGGESEW 24605

Query: 829   KYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEID 888
                S+PI  K  +          L+   +R    A  LV    G P+P + W + G EI 
Sbjct: 24606 SEISEPITPKSDVPIQAPHFKEELRNLNVRYQSNA-TLVCKVTGHPKPIVKWYRQGKEII 24664

Query: 889   KNQINIRNSE 898
              + +  R  E
Sbjct: 24665 ADGLKYRIQE 24674



 Score =  156 bits (395), Expect = 9e-38
 Identities = 103/340 (30%), Positives = 163/340 (47%), Gaps = 15/340 (4%)

Query: 516   ANALTEDEGDYVFAPDAYNVT---LPAKVHVIDPPKIILDGLDA----DNTVTVIAGNKL 568
             A  LTE + +Y F   A N      P+++ V+    ++   LD     D        +  
Sbjct: 13637 AKDLTEGK-EYTFRVSAENENGEGTPSEITVVARDDVVAPDLDLKGLPDLCYLAKENSNF 13695

Query: 569   RLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKN 628
             RL+IPI G+P P   W +G+  +   + R+  ES   ++TL++   ++ D+G Y I LKN
Sbjct: 13696 RLKIPIKGKPAPSVSWKKGEDPLATDT-RVSVESSAVNTTLIVYDCQKSDAGKYTITLKN 13754

Query: 629   EAGEAHASIKVKVVDFPDPPVAPT-VTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQ 687
              AG    +I +KVV  P  P  P    EV  +   + W PP  DGGS I  Y +E++   
Sbjct: 13755 VAGTKEGTISIKVVGKPGIPTGPIKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDSV 13814

Query: 688   SSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFV---PLAVTS 744
             +++W+       ++TTF   ++ EG+ Y  R+ A N  G+ +  + S P V   P  V  
Sbjct: 13815 NNKWVTCA-SAVQKTTFRVTRLHEGMEYTFRVSAENKYGVGE-GLKSEPIVARHPFDVPD 13872

Query: 745   PPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTI 804
              P    +  V   +V++ W  P   G + + GY LE+    +  W  ANK  I    F +
Sbjct: 13873 APPPPNIVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTPIRMRDFKV 13932

Query: 805   TGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPP 844
             TGL    +   RV A+N AG  +P   S+P++  + I+PP
Sbjct: 13933 TGLTEGLEYEFRVMAINLAGVGKPSLPSEPVVALDPIDPP 13972



 Score =  155 bits (391), Expect = 3e-37
 Identities = 98/310 (31%), Positives = 156/310 (50%), Gaps = 8/310 (2%)

Query: 547   PKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDS 606
             P++ L G+     V   AG+ +++EIP+ G P P   W +GD+ I++ + R+  E+   S
Sbjct: 14758 PELDLRGI-YQKLVIAKAGDNIKVEIPVLGRPKPTVTWKKGDQ-ILKQTQRVNFETTATS 14815

Query: 607   STLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPT-VTEVGDDWCIMNW 665
             + L I+   R DSG Y +  +N  GE    I ++V D P PP  P    EV  D+   +W
Sbjct: 14816 TILNINECVRSDSGPYPLTARNIVGEVGDVITIQVHDIPGPPTGPIKFDEVSSDFVTFSW 14875

Query: 666   EPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAI 725
             +PP  DGG PI  Y +E ++  S+ W+ L   + + TT++  ++  G+ Y+ R+ A N  
Sbjct: 14876 DPPENDGGVPISNYVVEMRQTDSTTWVELATTVIR-TTYKATRLTTGLEYQFRVKAQNRY 14934

Query: 726   GISKPSMPSRPFV---PLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYC 782
             G+  P + S   V   P  V  PP    V +VT  ++T+ W  P   G + + GY +E  
Sbjct: 14935 GVG-PGITSACIVANYPFKVPGPPGTPQVTAVTKDSMTISWHEPLSDGGSPILGYHVERK 14993

Query: 783   FEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIE 842
                   W   +K L+    F  +GL        RV A N AG S+P   S+P+L  + I+
Sbjct: 14994 ERNGILWQTVSKALVPGNIFKSSGLTDGIAYEFRVIAENMAGKSKPSKPSEPMLALDPID 15053

Query: 843   PPKIRIPRHL 852
             PP   +P ++
Sbjct: 15054 PPGKPVPLNI 15063



 Score =  154 bits (389), Expect = 5e-37
 Identities = 103/318 (32%), Positives = 157/318 (49%), Gaps = 10/318 (3%)

Query: 530   PDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDK 589
             P   +V + AK  VI P   +L      NT TV+AG  L++++P  G P P   W + D 
Sbjct: 15827 PRQLSVPVIAKDLVIPPAFKLLF-----NTFTVLAGEDLKVDVPFIGRPTPAVTWHK-DN 15880

Query: 590   AIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPV 649
               ++ + R+  ES  ++S L I  A R+D G Y + L N AGEA  ++ V V+D P PP 
Sbjct: 15881 VPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAGEAIETLNVIVLDKPGPPT 15940

Query: 650   APT-VTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKK 708
              P  + EV  D   ++W PP YDGGS I  Y +E++   ++ W  ++  + + TT +  +
Sbjct: 15941 GPVKMDEVTADSITLSWGPPKYDGGSSINNYIVEKRDTSTTTWQIVSATVAR-TTIKACR 15999

Query: 709   MIEGVAYEVRIFAVNAIGISK--PSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPP 766
             +  G  Y+ RI A N  G S    S P+    P  V  PP    V   +  ++ ++W  P
Sbjct: 16000 LKTGCEYQFRIAAENRYGKSTYLNSEPTVAQYPFKVPGPPGTPVVTLSSRDSMEVQWNEP 16059

Query: 767   DHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGAS 826
                G + + GY LE     +  W+  NK  I +TKF  TGL    +   RV A N  G  
Sbjct: 16060 ISDGGSRVIGYHLERKERNSILWVKLNKTPIPQTKFKTTGLEEGVEYEFRVSAENIVGIG 16119

Query: 827   EPKYYSQPILVKEIIEPP 844
             +P   S+  + ++  +PP
Sbjct: 16120 KPSKVSECYVARDPCDPP 16137



 Score =  149 bits (375), Expect = 2e-35
 Identities = 97/304 (31%), Positives = 142/304 (46%), Gaps = 5/304 (1%)

Query: 544   IDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESY 603
             ID P   LD    D  + V AG    LE  I G+P P  +WS+  K + E + R+  +S 
Sbjct: 18397 IDAPNASLDPKYKD-VIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKST 18455

Query: 604   PDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPT-VTEVGDDWCI 662
                +TLV+    R D G Y + L N  G     I VKV+D P PP  P  VT V  + C 
Sbjct: 18456 IQKTTLVVKDCIRTDGGQYILKLSNVGGTKSIPITVKVLDRPGPPEGPLKVTGVTAEKCY 18515

Query: 663   MNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAV 722
             + W PP  DGG+ I  Y IE+++     W +++ ++ +   ++  K++ G  Y  R+ AV
Sbjct: 18516 LAWNPPLQDGGANISHYIIEKRETSRLSWTQVSTEV-QALNYKVTKLLPGNEYIFRVMAV 18574

Query: 723   NAIGISKP--SMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLE 780
             N  GI +P  S P     P     PP+   V ++T  ++ + W  P   G   ++GY+LE
Sbjct: 18575 NKYGIGEPLESGPVTACNPYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILE 18634

Query: 781   YCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEI 840
                +    W   NK  +   +  +TGL        RV A NAAG  EP   S      + 
Sbjct: 18635 KRDKEGVRWTKCNKKTLTDLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRACDA 18694

Query: 841   IEPP 844
             + PP
Sbjct: 18695 LYPP 18698



 Score =  146 bits (369), Expect = 1e-34
 Identities = 189/864 (21%), Positives = 334/864 (38%), Gaps = 120/864 (13%)

Query: 297  FVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKC 356
            F VEL+   + VKW+KN Q +  +     + +G    +   +  + D S+  V A     
Sbjct: 5643 FTVELSHDNIRVKWFKNDQRLHTTRSVSMQDEGKTHSITFKDLSIDDTSQIRVEAMGMSS 5702

Query: 357  STELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRI 416
              +L V E     T +L+D T    + V L+CE+S+ DA VKWFK+G+EI P   +   I
Sbjct: 5703 EAKLTVLEGDPYFTGKLQDYTGVEKDEVILQCEISKADAPVKWFKDGKEIKPSKNA--VI 5760

Query: 417  RVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEIC 476
            + +GKK +LI++ A K+D  +Y+      ++S KL ++ + +K++ PL    V   +   
Sbjct: 5761 KADGKKRMLILKKALKSDIGQYTCDCGTDKTSGKLDIEDREIKLVRPLHSVEVMETETAR 5820

Query: 477  LKCEISE-NIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNV 535
             + EISE +I   W   G  + ++   ++  +G+IH LV+ N   +  G   F   A NV
Sbjct: 5821 FETEISEDDIHANWKLKGEALLQTPDCEIKEEGKIHSLVLHNCRLDQTGGVDF--QAANV 5878

Query: 536  TLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGS 595
               A + V   P++I   L     VTV AG     +  +S E  P   + +G K  +E S
Sbjct: 5879 KSSAHLRV--KPRVI-GLLRPLKDVTVTAGETATFDCELSYEDIPVEWYLKGKK--LEPS 5933

Query: 596  GRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTE 655
             ++   S     TL +   + +D+G   +  K+    A+  +K   V+F  P    TV E
Sbjct: 5934 DKVVPRSEGKVHTLTLRDVKLEDAGEVQLTAKDFKTHANLFVKEPPVEFTKPLEDQTVEE 5993

Query: 656  VGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFE------PKKM 709
                            G + +L   + R+  +  +W +   ++ K   +E       +K+
Sbjct: 5994 ----------------GATAVLECEVSRENAK-VKWFKNGTEILKSKKYEIVADGRVRKL 6036

Query: 710  I--EGVAYEVRIFAVNA--------IGISKPSMP-SRPFVPLAVTSPPTLLTVDSVTDTT 758
            +  +    +++ +  +A        + +  P +   RP   L V           ++   
Sbjct: 6037 VIHDCTPEDIKTYTCDAKDFKTSCNLNVVPPHVEFLRPLTDLQVREKEMARFECELSREN 6096

Query: 759  VTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVK 818
              ++W      GA    G   +   +G    +V NK L+D           +A+    V+
Sbjct: 6097 AKVKWFKD---GAEIKKGKKYDIISKGAVRILVINKCLLD----------DEAEYSCEVR 6143

Query: 819  AVNAAG----ASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKP 874
                +G      E   +++ +   E+ E   I++   +                    KP
Sbjct: 6144 TARTSGMLTVLEEEAVFTKNLANIEVSETDTIKLVCEV-------------------SKP 6184

Query: 875  RPELTWKKDGAE-IDKNQINIRNSETDTIIFIRKAERSHSGKYDLQV---KVDKFVETAS 930
              E+ W K   E I+  +  I       I+ I+ A    +G Y+ ++   + D  V+   
Sbjct: 6185 GAEVIWYKGDEEIIETGRYEILTEGRKRILVIQNAHLEDAGNYNCRLPSSRTDGKVKVHE 6244

Query: 931  IDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQ-KADKKSMEWFTVI 989
            +  + I +P   +I++     GE      +  K+        + +Q K D K++E     
Sbjct: 6245 LAAEFISKPQNLEILE-----GEKAEFVCSISKE-------SFPVQWKRDDKTLE----- 6287

Query: 990  EHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFD 1049
                           G++Y      +    + +DAT+      +   G            
Sbjct: 6288 --------------SGDKYDVIADGKKRVLVVKDATLQDMGTYVVMVGAA---RAAAHLT 6330

Query: 1050 FSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVC 1109
              E      PL +T          NC V      K  W +N+ AI D  +Y +     V 
Sbjct: 6331 VIEKLRIVVPLKDTRVKEQQEVVFNCEV-NTEGAKAKWFRNEEAIFDSSKYIILQKDLVY 6389

Query: 1110 TLEIRKPSPYDGGTYCCKAVNDLG 1133
            TL IR     D   Y     N  G
Sbjct: 6390 TLRIRDAHLDDQANYNVSLTNHRG 6413



 Score =  146 bits (369), Expect = 1e-34
 Identities = 96/339 (28%), Positives = 169/339 (49%), Gaps = 21/339 (6%)

Query: 521   EDEGDYVF---APDAYNVTLPAK----VHVID---PPKIILDGLDADNTVTVIAGNKLRL 570
             E++  Y F   A  A N++ P++    V ++    PP+I L  +   + +TV AG  + L
Sbjct: 12952 EEKAQYQFRAIARTAVNISPPSEPSDPVTILAENVPPRIDLS-VAMKSLLTVKAGTNVCL 13010

Query: 571   EIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEA 630
             +  + G+P P   W + D  +++ +  I+     +  TL +    R DSG Y I  +N +
Sbjct: 13011 DATVFGKPMPTVSWKK-DGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTITAENSS 13069

Query: 631   GEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSR 690
             G   A+IK+KV+D P PP +  + ++  D  +++WEPP  DGGS I  Y +++++     
Sbjct: 13070 GSKSATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYIVDKRETSRPN 13129

Query: 691   WMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGI-----SKPSMPSRPFVPLAVTSP 745
             W +++  +   T+   +K+IEG  Y+ RI A N  G+     ++P++   P+ P     P
Sbjct: 13130 WAQVSATV-PITSCSVEKLIEGHEYQFRICAENKYGVGDPVFTEPAIAKNPYDPPGRCDP 13188

Query: 746   PTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTIT 805
             P    + ++T   +T+ W+PP   G + + GY+LE       +W   N+  I +     T
Sbjct: 13189 P---VISNITKDHMTVSWKPPADDGGSPITGYLLEKRETQAVNWTKVNRKPIIERTLKAT 13245

Query: 806   GLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPP 844
             GL    +   RV A+N AG  +P   S+    ++   PP
Sbjct: 13246 GLQEGTEYEFRVTAINKAGPGKPSDASKAAYARDPQYPP 13284



 Score =  145 bits (365), Expect = 3e-34
 Identities = 110/374 (29%), Positives = 173/374 (46%), Gaps = 19/374 (5%)

Query: 288  QVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEY 347
            QV +    RF  EL+    +VKW+K+G EI+   KY    KG  RIL IN C + D++EY
Sbjct: 6079 QVREKEMARFECELSRENAKVKWFKDGAEIKKGKKYDIISKGAVRILVINKCLLDDEAEY 6138

Query: 348  YVTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEII 407
                   + S  L V E   + TK L +      + ++L CEVS+  A V W+K  EEII
Sbjct: 6139 SCEVRTARTSGMLTVLEEEAVFTKNLANIEVSETDTIKLVCEVSKPGAEVIWYKGDEEII 6198

Query: 408  PGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQ 467
                 RY I  EG+K IL+I+ A   DA  Y+      ++  K+ V     + ++   + 
Sbjct: 6199 --ETGRYEILTEGRKRILVIQNAHLEDAGNYNCRLPSSRTDGKVKVHELAAEFISKPQNL 6256

Query: 468  TVNLGKEICLKCEIS-ENIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDY 526
             +  G++    C IS E+ P +W ++   ++  D+  V+  G+   LV+ +A  +D G Y
Sbjct: 6257 EILEGEKAEFVCSISKESFPVQWKRDDKTLESGDKYDVIADGKKRVLVVKDATLQDMGTY 6316

Query: 527  VF----APDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKA 582
            V     A  A ++T+  K+ ++ P K        D  V          E+   G    KA
Sbjct: 6317 VVMVGAARAAAHLTVIEKLRIVVPLK--------DTRVKEQQEVVFNCEVNTEG---AKA 6365

Query: 583  MWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVV 642
             W R ++AI + S  I  +      TL I  A  DD   Y+++L N  GE   S    +V
Sbjct: 6366 KWFRNEEAIFDSSKYIILQK-DLVYTLRIRDAHLDDQANYNVSLTNHRGENVKSAANLIV 6424

Query: 643  DFPDPPVAPTVTEV 656
            +  D  +   + ++
Sbjct: 6425 EEEDLRIVEPLKDI 6438



 Score =  144 bits (362), Expect = 6e-34
 Identities = 89/302 (29%), Positives = 150/302 (49%), Gaps = 8/302 (2%)

Query: 547   PKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDS 606
             P   L G+  +  +T  AG+   +++PISG P PK  W   +  + E + R+   +  D 
Sbjct: 22340 PTADLTGI-TNQLITCKAGSPFTIDVPISGRPAPKVTWKLEEMRLKE-TDRVSITTTKDR 22397

Query: 607   STLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPT-VTEVGDDWCIMNW 665
             +TL +  + R DSG Y + L+N AG    S+ V V+  P P   P  V+ V  + C+++W
Sbjct: 22398 TTLTVKDSMRGDSGRYFLTLENTAGVKTFSVTVVVIGRPGPVTGPIEVSSVSAESCVLSW 22457

Query: 666   EPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAI 725
               P   GG+ I  Y +E+++  ++ W  +N  + K T  +   + + + Y  R+ + N  
Sbjct: 22458 GEPKDGGGTEITNYIVEKRESGTTAWQLVNSSV-KRTQIKVTHLTKYMEYSFRVSSENRF 22516

Query: 726   GISKPSMPSRPFV---PLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYC 782
             G+SKP + S P +   P    S PT   V  V+   +++RW  P H G + + GY +E  
Sbjct: 22517 GVSKP-LESAPIIAEHPFVPPSAPTRPEVYHVSANAMSIRWEEPYHDGGSKIIGYWVEKK 22575

Query: 783   FEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIE 842
                T  W+  NK    +  + +TGL    +   R  A+NAAG S+    S+PI+ +  ++
Sbjct: 22576 ERNTILWVKENKVPCLECNYKVTGLVEGLEYQFRTYALNAAGVSKASEASRPIMAQNPVD 22635

Query: 843   PP 844
              P
Sbjct: 22636 AP 22637



 Score =  142 bits (359), Expect = 1e-33
 Identities = 133/536 (24%), Positives = 207/536 (38%), Gaps = 70/536 (13%)

Query: 642  VDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKE 701
            +D P PP  PTV +VG     +NW  P +DGG+ I  Y IE  K  +  W+R+   +   
Sbjct: 7676 IDPPWPPGKPTVKDVGKTSVRLNWTKPEHDGGAKIESYVIEMLKTGTDEWVRVAEGVPTT 7735

Query: 702  TTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFV---PLAVTSPPTLLTVDSVTDTT 758
                P  M EG  Y  R+ AVN  G S+PS PS P +    L   SPP  L V ++T  T
Sbjct: 7736 QHLLPGLM-EGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLEVINITKNT 7794

Query: 759  VTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVK 818
              ++W  P+  G + +  Y++E      + W   +  + D TK T+T L   +    RV 
Sbjct: 7795 ADLKWTVPEKDGGSPITNYIVEKRDVRRKGWQTVDTTVKD-TKCTVTPLTEGSLYVFRVA 7853

Query: 819  AVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPEL 878
            A NA G S+       +L K+    P                G    L +    K   +L
Sbjct: 7854 AENAIGQSDYTEIEDSVLAKDTFTTP----------------GPPYALAVVDVTKRHVDL 7897

Query: 879  TW---KKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQI 935
             W   K DG    +  +  +     T    R  +   +   D   +V   +E   +  Q+
Sbjct: 7898 KWEPPKNDGGRPIQRYVIEKKERLGT----RWVKAGKTAGPDCNFRVTDVIEGTEVQFQV 7953

Query: 936  -----------------------IDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITG 972
                                      P PP  + + D   +++A+ W PP+ +G + I G
Sbjct: 7954 RAENEAGVGHPSEPTEILSIEDPTSPPSPPLDLHVTDAGRKHIAIAWKPPEKNGGSPIIG 8013

Query: 973  YTIQKADKKSMEWFTVIEHYHRTSATITE--LVIGNEYYFRVFSENMCGLSEDATMTKES 1030
            Y ++     + +W  V     +      E  +V   EY  RV + N  G+SE + +++  
Sbjct: 8014 YHVEMCPVGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAIGVSEPSEISEN- 8072

Query: 1031 AVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKN 1090
             V+A+D         E  D                I G   ++    R  P P ++W K+
Sbjct: 8073 -VVAKDPDCKPTIDLETHDI-------------IVIEGEKLSIPVPFRAVPVPTVSWHKD 8118

Query: 1091 KVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVKVI 1146
               +    R  M ++     LE+ K    D G Y     N LG+      + VKVI
Sbjct: 8119 GKEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSA--TASINVKVI 8172



 Score =  140 bits (352), Expect = 9e-33
 Identities = 91/298 (30%), Positives = 146/298 (48%), Gaps = 7/298 (2%)

Query: 546   PPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPD 605
             PPK  LD     + VT+ AG+ L L+  + G+P PK +W++GDK  ++   ++  +    
Sbjct: 22738 PPKAELDARLHGDLVTIRAGSDLVLDAAVGGKPEPKIIWTKGDKE-LDLCEKVSLQYTGK 22796

Query: 606   SSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNW 665
              +T VI   +R DSG Y + +KN +G    S+ VKV+D P P    TV+ V  + C + W
Sbjct: 22797 RATAVIKFCDRSDSGKYTLTVKNASGTKAVSVMVKVLDSPGPCGKLTVSRVTQEKCTLAW 22856

Query: 666   EPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAI 725
               P  DGG+ I  Y +ER++     W+ +  + C   ++   ++I+   Y  R+ AVN  
Sbjct: 22857 SLPQEDGGAEITHYIVERRETSRLNWVIVEGE-CPTLSYVVTRLIKNNEYIFRVRAVNKY 22915

Query: 726   GISKPSMPSRPFV---PLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYC 782
             G   P + S P V      + SPP +          + ++W  P+  G   +  Y+++  
Sbjct: 22916 GPGVP-VESEPIVARNSFTIPSPPGIPEEVGTGKEHIIIQWTKPESDGGNEISNYLVDKR 22974

Query: 783   FEGTEDWIVANKD-LIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKE 839
              + +  W   NKD ++  T+  +T L        RV AVNAAG SEP   S  I  +E
Sbjct: 22975 EKKSLRWTRVNKDYVVYDTRLKVTSLMEGCDYQFRVTAVNAAGNSEPSEASNFISCRE 23032



 Score =  139 bits (350), Expect = 2e-32
 Identities = 112/414 (27%), Positives = 188/414 (45%), Gaps = 21/414 (5%)

Query: 295  VRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDE 354
            + F V +    +  KW KNG EI+ + K     K     L I N    D ++Y   AG  
Sbjct: 2940 ITFEVTVNYEGISYKWLKNGVEIKSTDKCQMRTKKLTHSLNIRNVHFGDAADYTFVAGKA 2999

Query: 355  KCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRY 414
              +  L+V    I   K ++D      +R   ECEVSE D  V+W K+ +E+      R 
Sbjct: 3000 TSTATLYVEARHIEFRKHIKDIKVLEKKRAMFECEVSEPDITVQWMKDDQEL--QITDRI 3057

Query: 415  RIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKE 474
            +I+ E   H L+I     +DA +Y+V+  G  S+AKL V+ + ++I +   +  V   + 
Sbjct: 3058 KIQKEKYVHRLLIPSTRMSDAGKYTVVAGGNVSTAKLFVEGRDVRIRSIKKEVQVIEKQR 3117

Query: 475  ICLKCEISE-NIPGKWTKNGLPV--QESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPD 531
              ++ E++E ++   W K+G+ +  Q  +R K V + RIH++ I+     D G+Y F   
Sbjct: 3118 AVVEFEVNEDDVDAHWYKDGIEINFQVQERHKYVVERRIHRMFISETRQSDAGEYTFVAG 3177

Query: 532  AYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAI 591
                ++   V+  +PP++    L     VTV +G   R    ISG P PK  W + ++ +
Sbjct: 3178 RNRSSVTLYVNAPEPPQV----LQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLL 3233

Query: 592  MEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAG----EAHASIKVKVVDFPD- 646
              G  + +        TL++  A  +D+ VY    KN+ G     A  S++V  V  PD 
Sbjct: 3234 STGF-KCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQ 3292

Query: 647  --PPVAPTVTEVGDDWCIMNWEPPAY----DGGSPILGYFIERKKKQSSRWMRL 694
              P   P +     D      +P  +     G    + ++ + KK + SR+ R+
Sbjct: 3293 EMPVYPPAIITPLQDTVTSEGQPARFQCRVSGTDLKVSWYSKDKKIKPSRFFRM 3346



 Score =  139 bits (350), Expect = 2e-32
 Identities = 158/612 (25%), Positives = 260/612 (42%), Gaps = 77/612 (12%)

Query: 292   GGRVRFVVELAD-PKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVT 350
             GG +R  V +   P  EVKW K   EIR +   I +       L ++N    D  +Y +T
Sbjct: 16652 GGSLRLFVPIKGRPTPEVKWGKVDGEIRDAA--IIDVTSSFTSLVLDNVNRYDSGKYTLT 16709

Query: 351   AGDEKCSTELFVR-------EPPI--MVTKQLEDTTAYCGERVELECE-------VSEDD 394
               +   +   FV         PP+   VT+  +D+ +   E   L+         V + +
Sbjct: 16710 LENSSGTKSAFVTVRVLDTPSPPVNLKVTEITKDSVSITWEPPLLDGGSKIKNYIVEKRE 16769

Query: 395   ANVKWF--------KNG---EEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTT 443
             A  K +        KN    +++  G    +R+  E +  I        A  A+   +  
Sbjct: 16770 ATRKSYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAENEYGI-----GLPAQTADPIKVAE 16824

Query: 444   GGQSSAKLSVDLKPLKILTPLTDQTVNLG---KEICLKCEISENIPGKWTKNGLPVQESD 500
               Q   K++VD         +T  +V+L     E     +I + I     K+     E  
Sbjct: 16825 VPQPPGKITVD--------DVTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKHSEKWSECA 16876

Query: 501   RLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYN-----------VTLPAKVHVIDPPKI 549
             R+K +      + VI N LT+ E +Y+F   A N           V + AK  VI+P   
Sbjct: 16877 RVKSL------QAVITN-LTQGE-EYLFRVVAVNEKGRSDPRSLAVPIVAKDLVIEP--- 16925

Query: 550   ILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTL 609
               D   A ++ +V  G  L++E+PISG P P   W++ D   ++ + RI      D +TL
Sbjct: 16926 --DVKPAFSSYSVQVGQDLKIEVPISGRPKPTITWTK-DGLPLKQTTRINVTDSLDLTTL 16982

Query: 610   VIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPT-VTEVGDDWCIMNWEPP 668
              I    +DD G Y I + N  G+  ASI++  +D PDPP  P    +V  +   ++W PP
Sbjct: 16983 SIKETHKDDGGQYGITVANVVGQKTASIEIVTLDKPDPPKGPVKFDDVSAESITLSWNPP 17042

Query: 669   AYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGIS 728
              Y GG  I  Y ++++   ++ W  ++  + + TT +  K+  G  Y+ RIFA N  G S
Sbjct: 17043 LYTGGCQITNYIVQKRDTTTTVWDVVSATVAR-TTLKVTKLKTGTEYQFRIFAENRYGQS 17101

Query: 729   KPSMPSRPFV---PLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEG 785
               ++ S P V   P     PP      +++  ++ ++W  P + G + + GY LE     
Sbjct: 17102 F-ALESDPIVAQYPYKEPGPPGTPFATAISKDSMVIQWHEPVNNGGSPVIGYHLERKERN 17160

Query: 786   TEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPK 845
             +  W   NK +I  T+F    L    +   RV A N  G  +    S+  + ++  +PP 
Sbjct: 17161 SILWTKVNKTIIHDTQFKAQNLEEGIEYEFRVYAENIVGVGKASKNSECYVARDPCDPPG 17220

Query: 846   IRIPRHLKQTYI 857
                P  +K+  I
Sbjct: 17221 TPEPIMVKRNEI 17232



 Score =  138 bits (347), Expect = 3e-32
 Identities = 89/302 (29%), Positives = 146/302 (48%), Gaps = 6/302 (1%)

Query: 547   PKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDS 606
             P I+  G +  + + + +G  LR++  + G P P+  W + D   +E    +       S
Sbjct: 21650 PPIVEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVTWFK-DGVEIEKRMNMEITDVLGS 21708

Query: 607   STLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPT-VTEVGDDWCIMNW 665
             ++L +  A RD  GVY +  KN +G A A IKVKV D P   V P   T +  +   + W
Sbjct: 21709 TSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQDTPGKVVGPIRFTNITGEKMTLWW 21768

Query: 666   EPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAI 725
             + P  DG +PI  Y IE+++     W  +  D C+  ++   K+I G  Y+ R+ AVN  
Sbjct: 21769 DAPLNDGCAPITHYIIEKRETSRLAWALIE-DKCEAQSYTAIKLINGNEYQFRVSAVNKF 21827

Query: 726   GISKP--SMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCF 783
             G+ +P  S P    +   V   P +    ++T  ++T+ W  P+  G + +  Y+LE   
Sbjct: 21828 GVGRPLDSDPVVAQIQYTVPDAPGIPEPSNITGNSITLTWARPESDGGSEIQQYILERRE 21887

Query: 784   EGTEDWI-VANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIE 842
             + +  W+ V +K  I +T+F +TGL    +    V A NAAG       S+ I  +E + 
Sbjct: 21888 KKSTRWVKVISKRPISETRFKVTGLTEGNEYEFHVMAENAAGVGPASGISRLIKCREPVN 21947

Query: 843   PP 844
             PP
Sbjct: 21948 PP 21949



 Score =  136 bits (343), Expect = 1e-31
 Identities = 105/376 (27%), Positives = 169/376 (44%), Gaps = 13/376 (3%)

Query: 272  EEKKSAAFAKILDPAYQVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQ 331
            + K+   F + L      +K     F  E ++P ++VKWYK+G E+    KY        
Sbjct: 2123 QAKQLITFTQELQDVVAKEKDTMATFECETSEPFVKVKWYKDGMEVHEGDKYRMHSDRKV 2182

Query: 332  RILFINNCQMTDDSEY-YVTAGDE--KCSTELFVREPPIMVTKQLEDTTAYCGERVELEC 388
              L I     +D  +Y  V   DE  K + +L V    +   K+L+D         ELEC
Sbjct: 2183 HFLSILTIDTSDAEDYSCVLVEDENVKTTAKLIVEGAVVEFVKELQDIEVPESYSGELEC 2242

Query: 389  EVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSS 448
             VS ++   KW+ N  E+      +Y I     +  L ++  TK D  EYS +  G +++
Sbjct: 2243 IVSPENIEGKWYHNDVEL--KSNGKYTITSRRGRQNLTVKDVTKEDQGEYSFVIDGKKTT 2300

Query: 449  AKLSVDLKPLKILTPLTDQTVNLGKEICLKCEIS-ENIPGKWTKNGLPVQESDRLKVVHK 507
             KL +  +P+ IL  L+DQ V  G  + L+ ++S E++ G W K+G  VQ SDR+ +V  
Sbjct: 2301 CKLKMKPRPIAILQGLSDQKVCEGDIVQLEVKVSLESVEGVWMKDGQEVQPSDRVHIVID 2360

Query: 508  GRIHKLVIANALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNK 567
             + H L+I +   ED G+Y F   A  ++   +V V       +D +     V VI G K
Sbjct: 2361 KQSHMLLIEDMTKEDAGNYSFTIPALGLSTSGRVSVYS-----VDVITPLKDVNVIEGTK 2415

Query: 568  LRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLK 627
              LE  +S        W   D+ I +   R++         LVI+     D G Y + + 
Sbjct: 2416 AVLECKVSVPDVTSVKWYLNDEQI-KPDDRVQAIVKGTKQRLVINRTHASDEGPYKLIVG 2474

Query: 628  NEAGEAHASI-KVKVV 642
                  + S+ K+K++
Sbjct: 2475 RVETNCNLSVEKIKII 2490



 Score =  134 bits (338), Expect = 4e-31
 Identities = 201/832 (24%), Positives = 325/832 (39%), Gaps = 120/832 (14%)

Query: 362   VREPPIMVTKQLEDTTAY-CGERVELECEVS-EDDANVKWFKNGEEIIPGPKSRYRIRVE 419
             V  P I V  + +DT     GE   LE +VS      ++W K+G+E+     ++  I++ 
Sbjct: 15151 VEAPKIKVDVKFKDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKEL--EGTAKLEIKIA 15208

Query: 420   GKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKC 479
                  L+ + +T+ D+  Y++  T     AK   ++K L    P  +  + + +    KC
Sbjct: 15209 DFSTNLVNKDSTRRDSGAYTLTATNPGGFAKHIFNVKVLDRPGP-PEGPLAVTEVTSEKC 15267

Query: 480   EISENIP-----GKWTKNGLPVQESDRL---KVVHKGRIHKLVIANALTEDEGDY-VFAP 530
              +S   P      K     +  +E+ RL    V  + ++ KL +   L  +E  + V A 
Sbjct: 15268 VLSWFPPLDDGGAKIDHYIVQKRETSRLAWTNVASEVQVTKLKVTKLLKGNEYIFRVMAV 15327

Query: 531   DAYNVTLPAKVHVI---------DPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPK 581
             + Y V  P +   +         DPPK        +  VT I  + +   +   G P   
Sbjct: 15328 NKYGVGEPLESEPVLAVNPYGPPDPPK--------NPEVTTITKDSM---VVCWGHPDSD 15376

Query: 582   A-------MWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAG--- 631
                     +  R DKA      +   ++  D    V  + E  +   + I  +N AG   
Sbjct: 15377 GGSEIINYIVERRDKAGQRWI-KCNKKTLTDLRYKVSGLTEGHEYE-FRIMAENAAGISA 15434

Query: 632   EAHASIKVKVVDF---PDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQS 688
              +  S   K  D    P PP  P V +       + W  P YDGGS I GY +E    + 
Sbjct: 15435 PSPTSPFYKACDTVFKPGPPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIALPEE 15494

Query: 689   SRWMRLNFDL-CKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSM-PSRPFVPLAVTSPP 746
               W  +      K T++    + E   Y++RI+A+N+ G+ +P++ P  P     +  P 
Sbjct: 15495 DEWQIVTPPAGLKATSYTITGLTENQEYKIRIYAMNSEGLGEPALVPGTPKAEDRMLPPE 15554

Query: 747   TLLTVDSVTDTT----------VTMRWRPPDHIGAAGLDGYVLEYC-FEGTEDW---IVA 792
               L  D     T          V ++ RP   +  A   G  L+    E T  +   IV 
Sbjct: 15555 IELDADLRKVVTIRACCTLRLFVPIKGRPAPEVKWARDHGESLDKASIESTSSYTLLIVG 15614

Query: 793   NKDLIDKTKF--TITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEII--------E 842
             N +  D  K+  T+         FV V+ ++  G        Q + VKE+         +
Sbjct: 15615 NVNRFDSGKYILTVENSSGSKSAFVNVRVLDTPGPP------QDLKVKEVTKTSVTLTWD 15668

Query: 843   PPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTI 902
             PP +     +K  YI    E+             + +WK D  +           E  + 
Sbjct: 15669 PPLLDGGSKIKN-YIVEKRESTRKAYSTVATNCHKTSWKVDQLQ-----------EGCSY 15716

Query: 903   IFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPP 962
              F   AE  +         +    ETA   ++  +RP PP  + + DV   +V+L+W  P
Sbjct: 15717 YFRVLAENEYG--------IGLPAETAE-SVKASERPLPPGKITLMDVTRNSVSLSWEKP 15767

Query: 963   KDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSE 1022
             + DG + I GY ++   K S +W T       T ATIT L+ G EY FRV ++N  G+S+
Sbjct: 15768 EHDGGSRILGYIVEMQTKGSDKWATCAT-VKVTEATITGLIQGEEYSFRVSAQNEKGISD 15826

Query: 1023  DATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAI-AGYNATLNCSVRGNP 1081
                ++    VIA+D  I              P   + L NT+ + AG +  ++    G P
Sbjct: 15827 PRQLSVP--VIAKDLVI--------------PPAFKLLFNTFTVLAGEDLKVDVPFIGRP 15870

Query: 1082  KPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLG 1133
              P +TW K+ V +    R    S +    L I+     D G Y  K  N  G
Sbjct: 15871 TPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAG 15922



 Score =  131 bits (329), Expect = 4e-30
 Identities = 135/530 (25%), Positives = 203/530 (38%), Gaps = 77/530 (14%)

Query: 645   PDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNF-DLCKETT 703
             P PP  P V +       ++W  PAYDGGSPI+GY +E K+  S  W+R N     ++T 
Sbjct: 13284 PGPPAFPKVYDTTRSSVSLSWGKPAYDGGSPIIGYLVEVKRADSDNWVRCNLPQNLQKTR 13343

Query: 704   FEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPP----------TLLTVDS 753
             FE   ++E   Y+ R++AVN IG S PS       P  +  PP          TL+    
Sbjct: 13344 FEVTGLMEDTQYQFRVYAVNKIGYSDPSDVPDKHYPKDILIPPEGELDADLRKTLILRAG 13403

Query: 754   VT-DTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAK 812
             VT    V ++ RPP  I                   W   N +L D+    I    TD  
Sbjct: 13404 VTMRLYVPVKGRPPPKI------------------TWSKPNVNLRDRIGLDIKS--TDFD 13443

Query: 813   IFVRVKAVNAAGASE----------PKYYSQPILVKEIIEPP-KIRIPRHLKQT------ 855
              F+R + VN   A +           K Y+  + V +   PP  + +    K +      
Sbjct: 13444 TFLRCENVNKYDAGKYILTLENSCGKKEYTIVVKVLDTPGPPVNVTVKEISKDSAYVTWE 13503

Query: 856   --YIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHS 913
                I      +N V+  Q +     +W     E  K    + N E     F R    +  
Sbjct: 13504 PPIIDGGSPIINYVV--QKRDAERKSWSTVTTECSKTSFRVANLEEGKSYFFRVFAENEY 13561

Query: 914   GKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGY 973
             G  D     D         ++    PGP   +K+  V   + ++ W  P  DG + I GY
Sbjct: 13562 GIGDPGETRDA--------VKASQTPGPVVDLKVRSVSKSSCSIGWKKPHSDGGSRIIGY 13613

Query: 974   TIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVI 1033
              +    +++ +W  V++       +  +L  G EY FRV +EN  G    + +T    V+
Sbjct: 13614 VVDFLTEEN-KWQRVMKSL-SLQYSAKDLTEGKEYTFRVSAENENGEGTPSEIT----VV 13667

Query: 1034  ARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVA 1093
             ARD     + V  D D    P          A    N  L   ++G P P ++W K +  
Sbjct: 13668 ARD-----DVVAPDLDLKGLPDLCY-----LAKENSNFRLKIPIKGKPAPSVSWKKGEDP 13717

Query: 1094  IVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1143
             +  D R  + S+    TL +      D G Y     N  GT E    ++V
Sbjct: 13718 LATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKEGTISIKV 13767



 Score =  130 bits (328), Expect = 5e-30
 Identities = 80/234 (34%), Positives = 120/234 (51%), Gaps = 8/234 (3%)

Query: 297  FVVELADPKLE-VKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEK 355
            F VEL  P ++ V+W KNG  +  + KY    KG    L I NC + D+S Y    G   
Sbjct: 2680 FTVELTHPNVKGVQWIKNGVVLESNEKYAISVKGTIYSLRIKNCAIVDESVYGFRLGRLG 2739

Query: 356  CSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYR 415
             S  L V    + + K+ +D TA     V  E  VS D   VKWF    EI P  K  +R
Sbjct: 2740 ASARLHVET--VKIIKKPKDVTALENATVAFEVSVSHDTVPVKWFHKSVEIKPSDK--HR 2795

Query: 416  IRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEI 475
            +  E K H L+++  + +DA EY+ +   GQ   K  + ++ L I   + +  V   K  
Sbjct: 2796 LVSERKVHKLMLQNISPSDAGEYTAVV--GQLECKAKLFVETLHITKTMKNIEVPETKTA 2853

Query: 476  CLKCEISE-NIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVF 528
              +CE+S  N+P  W KNG+ ++ S++ K+V +G++H+L+I N  TED  +Y F
Sbjct: 2854 SFECEVSHFNVPSMWLKNGVEIEMSEKFKIVVQGKLHQLIIMNTSTEDSAEYTF 2907



 Score =  129 bits (324), Expect = 2e-29
 Identities = 123/461 (26%), Positives = 196/461 (42%), Gaps = 58/461 (12%)

Query: 488   KWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDY--VFAPDAYNVTLPAKVHVID 545
             KWTK G  +  S R  +       +LVI  A   D G Y  V         +  KV VI 
Sbjct: 23864 KWTKEGQDI--SKRAMIATSETHTELVIKEADRGDSGTYDLVLENKCGKKAVYIKVRVIG 23921

Query: 546   PPKIILDGLDADNTVTVIAGNKLRLEIPISGEPP------------------PKAMWSRG 587
              P      L+ D+             + +S  PP                  PKA W   
Sbjct: 23922 SPNSPEGPLEYDDIQV--------RSVRVSWRPPADDGGADILGYILERREVPKAAWYTI 23973

Query: 588   DKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAG-----EAHASIKVKV- 641
             D        R+R       ++LV+   + +    + ++ +N+ G     ++   +  K  
Sbjct: 23974 DS-------RVR------GTSLVVKGLKENVEYHFRVSAENQFGISKPLKSEEPVTPKTP 24020

Query: 642   VDFPDPPV-APTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCK 700
             ++ P+PP   P V +V      ++W  P  DGGS + GY+IERK+  + +W+R N     
Sbjct: 24021 LNPPEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRVTGYYIERKETSTDKWVRHNKTQIT 24080

Query: 701   ETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFV---PLAVTSPPTLLTVDSVTDT 757
              T +    ++    Y+ RI A N +G+S+ S  S P V   P    S P  L + S++  
Sbjct: 24081 TTMYTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCKDPFDKPSQPGELEILSISKD 24140

Query: 758   TVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRV 817
             +VT++W  P+  G   + GY +EY   G   W  +NK+ I   +FTI GL    +   RV
Sbjct: 24141 SVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERIKDKQFTIGGLLEATEYEFRV 24200

Query: 818   KAVNAAGASEPKYYSQPILVKEII-EPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRP 876
              A N  G S P+  +  I  K    E P IR  + +K     ++GEA  L     G+P P
Sbjct: 24201 FAENETGLSRPRRTAMSIKTKLTSGEAPGIR--KEMKDV-TTKLGEAAQLSCQIVGRPLP 24257

Query: 877   ELTWKKDGAEIDKNQINIRNSETDT-IIFIRKAERSHSGKY 916
             ++ W + G E+ +++    +S+  T  + +   E+   G Y
Sbjct: 24258 DIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVY 24298



 Score =  128 bits (322), Expect = 3e-29
 Identities = 101/352 (28%), Positives = 164/352 (46%), Gaps = 15/352 (4%)

Query: 289  VDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYY 348
            V +G    FV EL+  K+ V W+KN  ++  S   +   +G    L +    + D S+  
Sbjct: 5280 VKEGETATFVCELSHEKMHVVWFKNDAKLHTSRTVLISSEGKTHKLEMKEVTLDDISQIK 5339

Query: 349  VTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIP 408
                +   + +L V E     T +L D TA   + + L+CEVS+ D  VKWFK+GEEI+P
Sbjct: 5340 AQVKELSSTAQLKVLEADPYFTVKLHDKTAVEKDEITLKCEVSK-DVPVKWFKDGEEIVP 5398

Query: 409  GPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQT 468
             PK  Y I+ +G + IL I+ A   D  EY       ++ A ++V+ + +K+  PL    
Sbjct: 5399 SPK--YSIKADGLRRILKIKKADLKDKGEYVCDCGTDKTKANVTVEARLIKVEKPLYGVE 5456

Query: 469  VNLGKEICLKCEISE-NIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYV 527
            V +G+    + E+SE ++ G+W   G P+  S   +++  G+ H L++ N      G+  
Sbjct: 5457 VFVGETAHFEIELSEPDVHGQWKLKGQPLTASPDCEIIEDGKKHILILHNCQLGMTGEVS 5516

Query: 528  FAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRG 587
            F   A N    A + V + P I +  L   + V V   ++ + E  +S E P    W +G
Sbjct: 5517 F--QAANAKSAANLKVKELPLIFITPL---SDVKVFEKDEAKFECEVSRE-PKTFRWLKG 5570

Query: 588  DKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKV 639
             + I  G  R          ++VI  A  +D   Y      EA + H S K+
Sbjct: 5571 TQEI-TGDDRFELIKDGTKHSMVIKSAAFEDEAKYMF----EAEDKHTSGKL 5617



 Score =  127 bits (320), Expect = 5e-29
 Identities = 123/540 (22%), Positives = 217/540 (40%), Gaps = 60/540 (11%)

Query: 622   YHINLKNEAG---EAHASIKVKVVD---FPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSP 675
             Y +  +N AG    +  S  ++  D    P PP  P + + G     + W  P +DGG+P
Sbjct: 19750 YRVYAENAAGLSLPSETSPLIRAEDPVFLPSPPSKPKIVDSGKTTITIAWVKPLFDGGAP 19809

Query: 676   ILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSR 735
             I GY +E KK   + W + +    + T +    +  G  Y  R+ +VN +G S PS  S 
Sbjct: 19810 ITGYTVEYKKSDDTDW-KTSIQSLRGTEYTISGLTTGAEYVFRVKSVNKVGASDPSDSSD 19868

Query: 736   PFVPLAVTSPP----------TLLTVDSVTDT-TVTMRWRPPDHIGAAGLDGYVLEYCFE 784
             P +       P          TL+     + T TV  R RP  ++  +  D  +    + 
Sbjct: 19869 PQIAKEREEEPLFDIDSEMRKTLIVKAGASFTMTVPFRGRPVPNVLWSKPDTDLRTRAYV 19928

Query: 785   GTED----WIVANKDLIDKTKFTIT--GLPTDAKIFVRVKAVNAAGASEPKYYSQPILVK 838
              T D      + N +  D  K+T+T   + + A + + VK ++  G          I V+
Sbjct: 19929 DTTDSRTSLTIENANRNDSGKYTLTIQNVLSAASLTLVVKVLDTPGPPTN------ITVQ 19982

Query: 839   EIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSE 898
             ++ +   +     L        G A       + +   +  W       ++    + N +
Sbjct: 19983 DVTKESAV-----LSWDVPENDGGAPVKNYHIEKREASKKAWVSVTNNCNRLSYKVTNLQ 20037

Query: 899   TDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALT 958
                I + R      SG+ +  V +    ET    ++I ++P PP+ + +  +  ++V+LT
Sbjct: 20038 EGAIYYFRV-----SGENEFGVGIP--AETKE-GVKITEKPSPPEKLGVTSISKDSVSLT 20089

Query: 959   WTPPKDDGNAAITGYTIQKADKKSMEWF--TVIEHYHRTSATITELVIGNEYYFRVFSEN 1016
             W  P+ DG + I  Y ++  +K    W    V +  H   + + E    +EY+FRVF+EN
Sbjct: 20090 WLKPEHDGGSRIVHYVVEALEKGQKNWVKCAVAKSTHHVVSGLRE---NSEYFFRVFAEN 20146

Query: 1017  MCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCS 1076
               GLS+   +            +    + E  +  E  M   P    Y  AG N  ++  
Sbjct: 20147 QAGLSDPREL------------LLPVLIKEQLEPPEIDMKNFPSHTVYVRAGSNLKVDIP 20194

Query: 1077  VRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVE 1136
             + G P PK+T  ++ V +    R+         T+ +++    D G Y   A N  GT +
Sbjct: 20195 ISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADAGRYEITAANSSGTTK 20254



 Score =  125 bits (315), Expect = 2e-28
 Identities = 87/266 (32%), Positives = 123/266 (46%), Gaps = 11/266 (4%)

Query: 272  EEKKSAAFAKIL--DPAYQV---DKGGRVRFVVEL---ADPKLEVKWYKNGQEIRPSTKY 323
            +E  S A  K+L  DP + V   DK    +  + L       + VKW+K+G+EI PS KY
Sbjct: 5343 KELSSTAQLKVLEADPYFTVKLHDKTAVEKDEITLKCEVSKDVPVKWFKDGEEIVPSPKY 5402

Query: 324  IFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGER 383
              +  G +RIL I    + D  EY    G +K    + V    I V K L     + GE 
Sbjct: 5403 SIKADGLRRILKIKKADLKDKGEYVCDCGTDKTKANVTVEARLIKVEKPLYGVEVFVGET 5462

Query: 384  VELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTT 443
               E E+SE D + +W   G+ +   P     I  +GKKHILI+         E S    
Sbjct: 5463 AHFEIELSEPDVHGQWKLKGQPLTASPDC--EIIEDGKKHILILHNCQLGMTGEVSFQAA 5520

Query: 444  GGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCEIS-ENIPGKWTKNGLPVQESDRL 502
              +S+A L V   PL  +TPL+D  V    E   +CE+S E    +W K    +   DR 
Sbjct: 5521 NAKSAANLKVKELPLIFITPLSDVKVFEKDEAKFECEVSREPKTFRWLKGTQEITGDDRF 5580

Query: 503  KVVHKGRIHKLVIANALTEDEGDYVF 528
            +++  G  H +VI +A  EDE  Y+F
Sbjct: 5581 ELIKDGTKHSMVIKSAAFEDEAKYMF 5606



 Score =  123 bits (308), Expect = 1e-27
 Identities = 235/1057 (22%), Positives = 377/1057 (35%), Gaps = 113/1057 (10%)

Query: 121  KGKWMDLASKAGKHLQLKETFERHSRVYTFEMQIIKAKDNFAGNYRCEVTYKDKFDSCSF 180
            KG+W+    + GKHL L       S  +   + I   K +  G Y    TYK      S 
Sbjct: 2603 KGEWL----RDGKHLPLTNNIRSESDGHKRRLIIAATKLDDIGEY----TYKVATSKTSA 2654

Query: 181  DLEVH--ESTGTTPNIDIRSAFKRSGEGQEDAGELDFSGLLKRREVKQQEEEPQVDVWEL 238
             L+V   +   T  N+ +          +     +     +K   V +  E+  + V   
Sbjct: 2655 KLKVEAVKIKKTLKNLTVTETQDAVFTVELTHPNVKGVQWIKNGVVLESNEKYAISV--- 2711

Query: 239  LKNAKPSEYEKIAFQYGITDLRGMLKRLKRMRREEKKSAAFAKILDPAYQVD--KGGRVR 296
                K + Y        I D      RL R+    +      KI+     V   +   V 
Sbjct: 2712 ----KGTIYSLRIKNCAIVDESVYGFRLGRLGASARLHVETVKIIKKPKDVTALENATVA 2767

Query: 297  FVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKC 356
            F V ++   + VKW+    EI+PS K+    +     L + N   +D  EY    G  +C
Sbjct: 2768 FEVSVSHDTVPVKWFHKSVEIKPSDKHRLVSERKVHKLMLQNISPSDAGEYTAVVGQLEC 2827

Query: 357  STELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRI 416
              +LFV    + +TK +++      +    ECEVS  +    W KNG EI    K  ++I
Sbjct: 2828 KAKLFVE--TLHITKTMKNIEVPETKTASFECEVSHFNVPSMWLKNGVEIEMSEK--FKI 2883

Query: 417  RVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEIC 476
             V+GK H LII   +  D+AEY+ +    Q SA L+V   P+ I + L D  +N  ++  
Sbjct: 2884 VVQGKLHQLIIMNTSTEDSAEYTFVCGNDQVSATLTV--TPIMITSMLKD--INAEEKDT 2939

Query: 477  LKCEISENIPG---KWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPD-- 531
            +  E++ N  G   KW KNG+ ++ +D+ ++  K   H L I N    D  DY F     
Sbjct: 2940 ITFEVTVNYEGISYKWLKNGVEIKSTDKCQMRTKKLTHSLNIRNVHFGDAADYTFVAGKA 2999

Query: 532  AYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAI 591
                TL  +   I+  K I D       + V+   +   E  +S EP     W + D+  
Sbjct: 3000 TSTATLYVEARHIEFRKHIKD-------IKVLEKKRAMFECEVS-EPDITVQWMKDDQE- 3050

Query: 592  MEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIK---------VKVV 642
            ++ + RI+ +       L+I      D+G Y +        A   ++          K V
Sbjct: 3051 LQITDRIKIQKEKYVHRLLIPSTRMSDAGKYTVVAGGNVSTAKLFVEGRDVRIRSIKKEV 3110

Query: 643  DFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKET 702
               +   A    EV +D    +W    Y  G  I     ER K    R  R++     ET
Sbjct: 3111 QVIEKQRAVVEFEVNEDDVDAHW----YKDGIEINFQVQERHKYVVER--RIHRMFISET 3164

Query: 703  TFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTS--PPTLLTVDSVTDTTVT 760
                      VA   R      +   +P    +   P+ V S  P     V S       
Sbjct: 3165 RQSDAGEYTFVAGRNRSSVTLYVNAPEPPQVLQELQPVTVQSGKPARFCAVISGRPQP-K 3223

Query: 761  MRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAV 820
            + W   + + +    G+  ++  +G E            T   I   P DA ++   +A 
Sbjct: 3224 ISWYKEEQLLST---GFKCKFLHDGQE-----------YTLLLIEAFPEDAAVYT-CEAK 3268

Query: 821  NAAGASEPKYYSQPILVKEIIE--------PPKIRIPRHLKQTYIRRVGEAVNLVIPFQG 872
            N  G +     S  + V E++         PP I  P    Q  +   G+         G
Sbjct: 3269 NDYGVATTS-ASLSVEVPEVVSPDQEMPVYPPAIITP---LQDTVTSEGQPARFQCRVSG 3324

Query: 873  KPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVK--VDKFVETA- 929
                   + KD          +   E    + I +A     G Y       V +   TA 
Sbjct: 3325 TDLKVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTAN 3384

Query: 930  -SIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEW-FT 987
             S+++Q +DR    + V+ E    + VA +    ++   + I+   I+     S E+   
Sbjct: 3385 LSLEVQALDRQSSGKDVR-ESAKSQAVADSSFTKEE---SKISQKEIKSFQGSSYEYEVQ 3440

Query: 988  VIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYED 1047
            V E   ++S      V   +        +   LS+ A  T+ S   A++           
Sbjct: 3441 VFESVSQSSIHTAASVQDTQLC------HTASLSQIAESTELSKECAKEST--------- 3485

Query: 1048 FDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQG 1107
                EAP     L +     G  A   C ++ +    +TW      I +  R +   N  
Sbjct: 3486 ---GEAPKIFLHLQDVTVKCGDTAQFLCVLKDDSFIDVTWTHEGAKIEESERLKQSQNGN 3542

Query: 1108 VCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVK 1144
            +  L I      D G Y C   ND G       L V+
Sbjct: 3543 IQFLTICNVQLVDQGLYSCIVHNDCGERTTSAVLSVE 3579



 Score =  122 bits (306), Expect = 2e-27
 Identities = 197/849 (23%), Positives = 321/849 (37%), Gaps = 123/849 (14%)

Query: 344   DSEYYVTAGDEKCSTELFVREPPIMVTKQLEDTTAY-CGERVELECEV-SEDDANVKWFK 401
             DS   +TA DE       V  P I +  +  DT     GE   LE +V  +    ++W +
Sbjct: 17304 DSTGPITAKDE-------VELPRISMDPKFRDTIVVNAGETFRLEADVHGKPLPTIEWLR 17356

Query: 402   NGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKIL 461
               +EI     +R  I+    K +LI++ A + D  +Y +  +    S    V++K L   
Sbjct: 17357 GDKEI--EESARCEIKNTDFKALLIVKDAIRIDGGQYILRASNVAGSKSFPVNVKVLDRP 17414

Query: 462   TPLTDQTVNLGKEICLKCEISENIPGKWTKNGLPVQESDRLKVVHKGRIHKL-------- 513
              P  +  V +      KC ++ + P +    G  +       VV K    +L        
Sbjct: 17415 GP-PEGPVQVTGVTSEKCSLTWSPPLQ--DGGSDISHY----VVEKRETSRLAWTVVASE 17467

Query: 514   VIANALTEDE----GDYVF---APDAYNVTLPAK-VHVIDPPKIILDGLDADNTVTVIAG 565
             V+ N+L   +     +YVF   A + Y V  P +   V+     +L G      VT IA 
Sbjct: 17468 VVTNSLKVTKLLEGNEYVFRIMAVNKYGVGEPLESAPVLMKNPFVLPGPPKSLEVTNIAK 17527

Query: 566   NKLRLEIPISGEPPPKAMWSRGDKA--------IMEGSGRIRTESYPDSSTLVIDIAER- 616
             + + +             W+R D          I+E   R        +   + D+  R 
Sbjct: 17528 DSMTV------------CWNRPDSDGGSEIIGYIVEKRDRSGIRWIKCNKRRITDLRLRV 17575

Query: 617   -----DDSGVYHINLKNEAGEAH---ASIKVKVVD---FPDPPVAPTVTEVGDDWCIMNW 665
                  D    + ++ +N AG      A++  K  D    P PP    + +   +   + W
Sbjct: 17576 TGLTEDHEYEFRVSAENAAGVGEPSPATVYYKACDPVFKPGPPTNAHIVDTTKNSITLAW 17635

Query: 666   EPPAYDGGSPILGYFIERKKKQSSRWMRLNFDL-CKETTFEPKKMIEGVAYEVRIFAVNA 724
               P YDGGS ILGY +E  K     W  +      + T FE  K+ E   Y++R+ A+N 
Sbjct: 17636 GKPIYDGGSEILGYVVEICKADEEEWQIVTPQTGLRVTRFEISKLTEHQEYKIRVCALNK 17695

Query: 725   IGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMR------------WRPPDHIGAA 772
             +G+ + +       P      P L  +DS     + +R             RP   I  +
Sbjct: 17696 VGLGEATSVPGTVKPEDKLEAPEL-DLDSELRKGIVVRAGGSARIHIPFKGRPTPEITWS 17754

Query: 773   GLDG-YVLEYCFEGTEDWI---VANKDLIDKTKFTIT--GLPTDAKIFVRVKAVNAAGAS 826
               +G +  +   E   ++    + N D  D  K+ +           FV VK ++  G  
Sbjct: 17755 REEGEFTDKVQIEKGVNYTQLSIDNCDRNDAGKYILKLENSSGSKSAFVTVKVLDTPGPP 17814

Query: 827   EPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAE 886
                   Q + VKE+ +     +    +   I    +  N VI  +   R    +    ++
Sbjct: 17815 ------QNLAVKEVRKDSAFLV---WEPPIIDGGAKVKNYVIDKRESTRK--AYANVSSK 17863

Query: 887   IDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVK 946
               K    + N     I + R    +  G       V   VET    ++  + P PP  V 
Sbjct: 17864 CSKTSFKVENLTEGAIYYFRVMAENEFG-------VGVPVETVDA-VKAAEPPSPPGKVT 17915

Query: 947   IEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGN 1006
             + DV   + +L W  P+ DG + + GY ++   K + +W  V E     +A +T L  G 
Sbjct: 17916 LTDVSQTSASLMWEKPEHDGGSRVLGYVVEMQPKGTEKWSIVAES-KVCNAVVTGLSSGQ 17974

Query: 1007  EYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAI 1066
             EY FRV + N  G S+   +     VIA+D  I              P    P  NTY+I
Sbjct: 17975 EYQFRVKAYNEKGKSDPRVLGVP--VIAKDLTIQ-------------PSLKLPF-NTYSI 18018

Query: 1067  -AGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYC 1125
              AG +  +   V G P+P I+W+K+   +    R  +        L I++ +  D G Y 
Sbjct: 18019 QAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKYT 18078

Query: 1126  CKAVNDLGT 1134
               A N  GT
Sbjct: 18079 VTATNSAGT 18087



 Score =  121 bits (304), Expect = 3e-27
 Identities = 185/870 (21%), Positives = 323/870 (37%), Gaps = 146/870 (16%)

Query: 338   NCQMTDDSEYYVTAGDEKCSTELFVREPPIMVTKQLEDT-TAYCGERVELECEV-SEDDA 395
             N     DS   +TA DE       +  P   +  + +D    + GE   LE ++  +   
Sbjct: 18380 NFSEPSDSSGAITARDE-------IDAPNASLDPKYKDVIVVHAGETFVLEADIRGKPIP 18432

Query: 396   NVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEY--SVMTTGGQSSAKLSV 453
             +V W K+G+E+     +R  I+   +K  L+++   + D  +Y   +   GG  S  ++V
Sbjct: 18433 DVVWSKDGKEL-EETAARMEIKSTIQKTTLVVKDCIRTDGGQYILKLSNVGGTKSIPITV 18491

Query: 454   DLK--------PLKIL------------TPLTDQTVNLGKEICLKCEISENIPGKWTKNG 493
              +         PLK+              PL D   N+   I  K E S      WT+  
Sbjct: 18492 KVLDRPGPPEGPLKVTGVTAEKCYLAWNPPLQDGGANISHYIIEKRETSRL---SWTQVS 18548

Query: 494   LPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVF---APDAYNVTLPAKVHVID----- 545
               VQ  +        ++ KL+  N       +Y+F   A + Y +  P +   +      
Sbjct: 18549 TEVQALNY-------KVTKLLPGN-------EYIFRVMAVNKYGIGEPLESGPVTACNPY 18594

Query: 546   -----PPKIILDGLDADNTVTVIA------GNKLRLEIPISGEPPPKAMWSRGDKAIMEG 594
                  P    +  +  D+ V   A      G ++   I +         W++ +K  +  
Sbjct: 18595 KPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYI-LEKRDKEGVRWTKCNKKTLTD 18653

Query: 595   SGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGE-AHASIKVKVVDF---PDPPVA 650
               R+R     +  +    +A  + +GV         GE +  S+  +  D    P PP  
Sbjct: 18654 L-RLRVTGLTEGHSYEFRVAAENAAGV---------GEPSEPSVFYRACDALYPPGPPSN 18703

Query: 651   PTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETT------F 704
             P VT+       + W  P YDGG+P+ GY +E K+  +  W       C   T      F
Sbjct: 18704 PKVTDTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAADEWTT-----CTPPTGLQGKQF 18758

Query: 705   EPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTL-----------LTVDS 753
                K+ E   Y  RI A+N+ G+ +P+      V      PP +           L   +
Sbjct: 18759 TVTKLKENTEYNFRICAINSEGVGEPATLPGSVVAQERIEPPEIELDADLRKVVVLRASA 18818

Query: 754   VTDTTVTMRWRPPDHIGAAGLDGYVLEYC-FEGTEDW---IVANKDLIDKTKFTIT--GL 807
                  VT++ RP   +     +G + +    E T  +   ++ N    D  ++ +T    
Sbjct: 18819 TLRLFVTIKGRPEPEVKWEKAEGILTDRAQIEVTSSFTMLVIDNVTRFDSGRYNLTLENN 18878

Query: 808   PTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLV 867
                   FV V+ +++  A        P+ +  I E  K  +    +   I    +  N +
Sbjct: 18879 SGSKTAFVNVRVLDSPSA--------PVNLT-IREVKKDSVTLSWEPPLIDGGAKITNYI 18929

Query: 868   IPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVE 927
             +  +   R       +     K    I N +     + R      S +Y + +  +    
Sbjct: 18930 VEKRETTRKAYATITNNCT--KTTFRIENLQEGCSYYFRVLA---SNEYGIGLPAE---- 18980

Query: 928   TASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFT 987
               +  +++ + P PP  V + DV      + W  P+ DG + ITGY ++   K S +W T
Sbjct: 18981 -TTEPVKVSEPPLPPGRVTLVDVTRNTATIKWEKPESDGGSKITGYVVEMQTKGSEKWST 19039

Query: 988   VIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYED 1047
               +      ATI+ L  G EY FRV + N  G S+   +     VIARD +I        
Sbjct: 19040 CTQ-VKTLEATISGLTAGEEYVFRVAAVNEKGRSDPRQLGVP--VIARDIEI-------- 19088

Query: 1048  FDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQG 1107
                   P    P       A     ++   +G P+  + W K+   + +  R  + S++ 
Sbjct: 19089 -----KPSVELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKT 19143

Query: 1108  VCTLEIRKPSPYDGGTYCCKAVNDLGTVEI 1137
             V +L I++ S  D GTY     N  G++ +
Sbjct: 19144 VTSLSIKEASKEDVGTYELCVSNSAGSITV 19173



 Score =  120 bits (302), Expect = 6e-27
 Identities = 142/561 (25%), Positives = 214/561 (38%), Gaps = 83/561 (14%)

Query: 622   YHINLKNEAGEAHASIKVKVVDF------PDPPVAPTVTEVGDDWCIMNWEPPAYDGGSP 675
             + ++ +NE G    S   K V        P PPV P   +   +   + W+PP +DGGS 
Sbjct: 10779 FRVSAENEIGIGDPSPPSKPVFAKDPIAKPSPPVNPEAIDTTCNSVDLTWQPPRHDGGSK 10838

Query: 676   ILGYFIERKKKQSSRWMRLNF--DLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMP 733
             ILGY +E +K     W R N   + C ET ++   + +G  Y+ R+ AVNA G S P+  
Sbjct: 10839 ILGYIVEYQKVGDEEWRRANHTPESCPETKYKVTGLRDGQTYKFRVLAVNAAGESDPAHV 10898

Query: 734   SRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTE----DW 789
               P +      PP L     + D  +        HI     D   L    +G       W
Sbjct: 10899 PEPVLVKDRLEPPEL-----ILDANMARE----QHIKVG--DTLRLSAIIKGVPFPKVTW 10947

Query: 790   IVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAG----ASEPKYYSQPILVKEIIEPPK 845
                ++D   K +  +T  P  +K+ +R  A    G      E    S+ + VK ++   K
Sbjct: 10948 KKEDRDAPTKARIDVT--PVGSKLEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLD-K 11004

Query: 846   IRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKK---DGAEIDKNQINIRNSETD-- 900
                PR L+ + IR              K    LTWK+   DG  +  N +  R       
Sbjct: 11005 PGPPRDLEVSEIR--------------KDSCYLTWKEPLDDGGSVITNYVVERRDVASAQ 11050

Query: 901   -TIIFIRKAERSHSGKY-------------DLQVKVDKFVETASIDIQIIDR---PGPPQ 943
              + +     ++SH  K+             + Q     FVET    I+ +D    PGPP+
Sbjct: 11051 WSPLSATSKKKSHFAKHLNEGNQYLFRVAAENQYGRGPFVETPK-PIKALDPLHPPGPPK 11109

Query: 944   IVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELV 1003
              +   DV    V+L W  P  DG + ITGY ++  ++ + +W    +        +T L 
Sbjct: 11110 DLHHVDVDKTEVSLVWNKPDRDGGSPITGYLVEYQEEGTQDWIK-FKTVTNLECVVTGLQ 11168

Query: 1004  IGNEYYFRVFSENMCGLS-EDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVN 1062
              G  Y FRV +EN+ GL   D T+  E        K+    V  D    E  +       
Sbjct: 11169 QGKTYRFRVKAENIVGLGLPDTTIPIEC-----QEKLVPPSVELDVKLIEGLVVK----- 11218

Query: 1063  TYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGG 1122
                 AG        +RG P P   W  +   I  D  Y + ++     L I+     D G
Sbjct: 11219 ----AGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTG 11274

Query: 1123  TYCCKAVNDLGTVEIECKLEV 1143
              Y     N  G+  +   L V
Sbjct: 11275 EYQITVSNAAGSKTVAVHLTV 11295



 Score =  120 bits (301), Expect = 7e-27
 Identities = 89/317 (28%), Positives = 143/317 (45%), Gaps = 11/317 (3%)

Query: 281  KILDPAYQVD--KGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINN 338
            K++ P + V+  +    RF  E+++  +   W   G+ +  +     + +G    L ++N
Sbjct: 5803 KLVRPLHSVEVMETETARFETEISEDDIHANWKLKGEALLQTPDCEIKEEGKIHSLVLHN 5862

Query: 339  CQMTDDSEYYVTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVK 398
            C++         A + K S  L V+   I + + L+D T   GE    +CE+S +D  V+
Sbjct: 5863 CRLDQTGGVDFQAANVKSSAHLRVKPRVIGLLRPLKDVTVTAGETATFDCELSYEDIPVE 5922

Query: 399  WFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPL 458
            W+  G+++ P  K     R EGK H L +      DA E  +     ++ A L V   P+
Sbjct: 5923 WYLKGKKLEPSDK--VVPRSEGKVHTLTLRDVKLEDAGEVQLTAKDFKTHANLFVKEPPV 5980

Query: 459  KILTPLTDQTVNLGKEICLKCEIS-ENIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIAN 517
            +   PL DQTV  G    L+CE+S EN   KW KNG  + +S + ++V  GR+ KLVI +
Sbjct: 5981 EFTKPLEDQTVEEGATAVLECEVSRENAKVKWFKNGTEILKSKKYEIVADGRVRKLVIHD 6040

Query: 518  ALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGE 577
               ED   Y    DA +      ++V+ P    L  L     + V      R E  +S E
Sbjct: 6041 CTPEDIKTYTC--DAKDFKTSCNLNVVPPHVEFLRPL---TDLQVREKEMARFECELSRE 6095

Query: 578  PPPKAMWSRGDKAIMEG 594
               K  W +    I +G
Sbjct: 6096 -NAKVKWFKDGAEIKKG 6111



 Score =  119 bits (298), Expect = 2e-26
 Identities = 113/439 (25%), Positives = 181/439 (41%), Gaps = 46/439 (10%)

Query: 621   VYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYF 680
             V  INL      +  S  V  +D  DPP  P V  +  +   + W  P YDGG  + GY 
Sbjct: 13945 VMAINLAGVGKPSLPSEPVVALDPIDPPGKPEVINITRNSVTLIWTEPKYDGGHKLTGYI 14004

Query: 681   IERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIG-ISKPSMPSRPFVP 739
             +E++   S  WM+ N     E  F    ++EG  YE RI A N  G IS PS  +   + 
Sbjct: 14005 VEKRDLPSKSWMKANHVNVPECAFTVTDLVEGGKYEFRIRAKNTAGAISAPSESTETIIC 14064

Query: 740   LAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDK 799
                   PT++   ++ D  +T++      + A  + G  L         W  A KD+   
Sbjct: 14065 KDEYEAPTIVLDPTIKD-GLTIKAGDTIVLNAISILGKPLP-----KSSWSKAGKDIRPS 14118

Query: 800   TKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRR 859
                 IT  PT + + ++      AG       + P   K            H+K T +  
Sbjct: 14119 DITQITSTPTSSMLTIKYATRKDAG-EYTITATNPFGTK----------VEHVKVTVLDV 14167

Query: 860   VGEAVNLVIPFQGKPRPELTWK---KDGAEIDKNQINIRNSETDTIIFIRKAERSHS--- 913
              G    + I      +  LTW    +DG    K+ I +   ET  +++   +E   S   
Sbjct: 14168 PGPPGPVEISNVSAEKATLTWTPPLEDGGSPIKSYI-LEKRETSRLLWTVVSEDIQSCRH 14226

Query: 914   --------GKYDLQVKV----DKFVETASIDIQIIDR---PGPPQIVKIEDVWGENVALT 958
                      +Y  +V       K     S  ++++DR   PGPP+  ++ +V      ++
Sbjct: 14227 VATKLIQGNEYIFRVSAVNHYGKGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTATVS 14286

Query: 959   WTPPKDDGNAAITGYTIQKADKKSMEWFTVIE-HYHRTSATITELVIGNEYYFRVFSENM 1017
             W  P DDG + ITGY +++ +KKS+ W   I+         +T L  G+ Y FRV +EN 
Sbjct: 14287 WKRPVDDGGSEITGYHVERREKKSLRWVRAIKTPVSDLRCKVTGLQEGSTYEFRVSAENR 14346

Query: 1018  CGL-----SEDATMTKESA 1031
              G+     + D+ + K++A
Sbjct: 14347 AGIGPPSEASDSVLMKDAA 14365



 Score =  116 bits (291), Expect = 1e-25
 Identities = 187/859 (21%), Positives = 324/859 (37%), Gaps = 143/859 (16%)

Query: 349   VTAGDEKCSTELFVREPPIMVTKQLEDT-TAYCGERVELECEV-SEDDANVKWFKNGEEI 406
             +TA DE       V  P I +  + +DT   + GE  +++ ++  +    ++W K  +E+
Sbjct: 16227 ITARDE-------VDPPRISMDPKYKDTIVVHAGESFKVDADIYGKPIPTIQWIKGDQEL 16279

Query: 407   IPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTD 466
                  +R  I+       L ++ A + D+  Y +          ++V++K L    P   
Sbjct: 16280 --SNTARLEIKSTDFATSLSVKDAVRVDSGNYILKAKNVAGERSVTVNVKVLDRPGPPEG 16337

Query: 467   QTVNLGKEICLKCEISENIPGKWTKNGLPVQE--SDRLKVVHKGR-----IHKLVIANAL 519
               V  G     KC ++      W     P+Q+  SD +  + + R     +  +V AN  
Sbjct: 16338 PVVISGVT-AEKCTLA------WKP---PLQDGGSDIINYIVERRETSRLVWTVVDANVQ 16387

Query: 520   TED-------EG-DYVF---APDAYNVTLPAKVH--VIDPPKIILDGLDADNTVTVIAGN 566
             T         EG +Y F   A + Y V  P +    V   P ++ D   A    TV   +
Sbjct: 16388 TLSCKVTKLLEGNEYTFRIMAVNKYGVGEPLESEPVVAKNPFVVPDAPKAPEVTTVTKDS 16447

Query: 567   KLRL-EIPISG------------EPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDI 613
              + + E P S                    W+R  K ++ G  R+R          V  +
Sbjct: 16448 MIVVWERPASDGGSEILGYVLEKRDKEGIRWTRCHKRLI-GELRLR----------VTGL 16496

Query: 614   AERDDSGVYHINLKNEAGEAHAS---IKVKVVD---FPDPPVAPTVTEVGDDWCIMNWEP 667
              E  D   + ++ +N AG +  S      K  D    P PP  P V ++      ++W  
Sbjct: 16497 IENHDYE-FRVSAENAAGLSEPSPPSAYQKACDPIYKPGPPNNPKVIDITRSSVFLSWSK 16555

Query: 668   PAYDGGSPILGYFIERKKKQSSRWMRLNFDL-CKETTFEPKKMIEGVAYEVRIFAVNAIG 726
             P YDGG  I GY +E+       W          +T  E +K++E   Y  RI A+N  G
Sbjct: 16556 PIYDGGCEIQGYIVEKCDVSVGEWTMCTPPTGINKTNIEVEKLLEKHEYNFRICAINKAG 16615

Query: 727   ISKPSMPSRPFVPLAVTSPPTL-----------LTVDSVTDTTVTMRWRPPDHIGAAGLD 775
             + + +    P +       P +           +         V ++ RP   +    +D
Sbjct: 16616 VGEHADVPGPIIVEEKLEAPDIDLDLELRKIINIRAGGSLRLFVPIKGRPTPEVKWGKVD 16675

Query: 776   GYVLEYCF----EGTEDWIVANKDLIDKTKFTIT--GLPTDAKIFVRVKAVNAAGASEPK 829
             G + +             ++ N +  D  K+T+T          FV V+ ++    S P 
Sbjct: 16676 GEIRDAAIIDVTSSFTSLVLDNVNRYDSGKYTLTLENSSGTKSAFVTVRVLDTP--SPPV 16733

Query: 830   YYSQPILVKEII----EPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGA 885
                   + K+ +    EPP +     +K   + +                 E T K   A
Sbjct: 16734 NLKVTEITKDSVSITWEPPLLDGGSKIKNYIVEK----------------REATRKSYAA 16777

Query: 886   EID---KNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPP 942
              +    KN   I   +     + R    +  G       +    +TA   I++ + P PP
Sbjct: 16778 VVTNCHKNSWKIDQLQEGCSYYFRVTAENEYG-------IGLPAQTAD-PIKVAEVPQPP 16829

Query: 943   QIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITEL 1002
               + ++DV   +V+L+WT P+ DG + I  Y ++   K S +W +         A IT L
Sbjct: 16830 GKITVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKHSEKW-SECARVKSLQAVITNL 16888

Query: 1003  VIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVN 1062
               G EY FRV + N  G S+  ++     ++A+D  I  +               +P  +
Sbjct: 16889 TQGEEYLFRVVAVNEKGRSDPRSLAVP--IVAKDLVIEPD--------------VKPAFS 16932

Query: 1063  TYAI-AGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDG 1121
             +Y++  G +  +   + G PKP ITW K+ + +    R  +  +  + TL I++    DG
Sbjct: 16933 SYSVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDG 16992

Query: 1122  GTYCCKAVNDLG--TVEIE 1138
             G Y     N +G  T  IE
Sbjct: 16993 GQYGITVANVVGQKTASIE 17011



 Score =  115 bits (287), Expect = 3e-25
 Identities = 101/370 (27%), Positives = 158/370 (42%), Gaps = 34/370 (9%)

Query: 291  KGGRVRFVVELAD-----------------PKLEVKWYKNGQEIRPSTKYIFEHKGCQRI 333
            +G  V FV EL D                   +E KWY N  E++ + KY    +  ++ 
Sbjct: 2217 EGAVVEFVKELQDIEVPESYSGELECIVSPENIEGKWYHNDVELKSNGKYTITSRRGRQN 2276

Query: 334  LFINNCQMTDDSEYYVTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSED 393
            L + +    D  EY      +K + +L ++  PI + + L D     G+ V+LE +VS +
Sbjct: 2277 LTVKDVTKEDQGEYSFVIDGKKTTCKLKMKPRPIAILQGLSDQKVCEGDIVQLEVKVSLE 2336

Query: 394  DANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSV 453
                 W K+G+E+   P  R  I ++ + H+L+IE  TK DA  YS        S    V
Sbjct: 2337 SVEGVWMKDGQEV--QPSDRVHIVIDKQSHMLLIEDMTKEDAGNYSFTIPALGLSTSGRV 2394

Query: 454  DLKPLKILTPLTDQTVNLGKEICLKCEIS--ENIPGKWTKNGLPVQESDRLKVVHKGRIH 511
             +  + ++TPL D  V  G +  L+C++S  +    KW  N   ++  DR++ + KG   
Sbjct: 2395 SVYSVDVITPLKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVKGTKQ 2454

Query: 512  KLVIANALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLE 571
            +LVI      DEG Y              V  I     I+ GL  D T T        +E
Sbjct: 2455 RLVINRTHASDEGPYKLIVGRVETNCNLSVEKIK----IIRGL-RDLTCTETQNVVFEVE 2509

Query: 572  IPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAG 631
            +  SG      +W+  DK I + S + + E++     L +    +DD G Y       AG
Sbjct: 2510 LSHSG---IDVLWNFKDKEI-KPSSKYKIEAHGKIYKLTVLNMMKDDEGKYTF----YAG 2561

Query: 632  EAHASIKVKV 641
            E   S K+ V
Sbjct: 2562 ENMTSGKLTV 2571



 Score =  115 bits (287), Expect = 3e-25
 Identities = 182/792 (22%), Positives = 302/792 (38%), Gaps = 105/792 (13%)

Query: 398   KWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKP 457
             KW  +G EI       Y +  +    +L I+   + D  EY +  +    S  ++V L  
Sbjct: 11238 KWTTDGSEI--KTDEHYTVETDNFSSVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTV 11295

Query: 458   LKILTPLTDQTVNLG---KEICLKCEISENIPGKWTKNGLPVQESDRLK----VVHKGRI 510
             L +  P T     L    + + +  +  ++  G    N + V++ D  K    VV  G  
Sbjct: 11296 LDVPGPPTGPINILDVTPEHMTISWQPPKDDGGSPVINYI-VEKQDTRKDTWGVVSSGSS 11354

Query: 511   H-KLVIANALTEDEGDYVFAPDAYNV---------TLPAKVHVIDPPKIILDGLDADNTV 560
               KL I +   +   +YVF   A N          T     H   PP            V
Sbjct: 11355 KTKLKIPHL--QKGCEYVFRVRAENKIGVGPPLDSTPTVAKHKFSPPSP-----PGKPVV 11407

Query: 561   TVIAGNKLRLE--IPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERD- 617
             T I  N   +   +P S    P   +    + +     R+      D    V  + E + 
Sbjct: 11408 TDITENAATVSWTLPKSDGGSPITGYYMERREVTGKWVRVNKTPIADLKFRVTGLYEGNT 11467

Query: 618   -DSGVYHINLKNEAGEAHASIKVKV---VDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGG 673
              +  V+  NL   +  + +S  +K    +  P PP+ P + +   +   + W  P  DGG
Sbjct: 11468 YEFRVFAENLAGLSKPSPSSDPIKACRPIKPPGPPINPKLKDKSRETADLVWTKPLSDGG 11527

Query: 674   SPILGYFIERKKKQSSRWMRLNFD-LCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSM 732
             SPILGY +E +K  +++W R+N D L ++  F    +IEG  Y  RI A N +G  +P  
Sbjct: 11528 SPILGYVVECQKPGTAQWNRINKDELIRQCAFRVPGLIEGNEYRFRIKAANIVGEGEPRE 11587

Query: 733   PSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVA 792
              +   +   +  PP +  +D      +T+R      I  A + G       E    W   
Sbjct: 11588 LAESVIAKDILHPPEV-ELDVTCRDVITVRVGQTIRI-LARVKGRP-----EPDITWTKE 11640

Query: 793   NKDLI-DKTKFTITGLPTDAKIFVRVKAVNAAGASEPKY---------YSQPILVKEIIE 842
              K L+ +K    I  LP      V ++   A  A   KY         ++Q   +  +++
Sbjct: 11641 GKVLVREKRVDLIQDLPR-----VELQIKEAVRADHGKYIISAKNSSGHAQGSAIVNVLD 11695

Query: 843   PPKIRIPRHLKQTYIRRVG--------------EAVNLVIPFQGKPRPELTWKKDGAEID 888
              P     ++LK T + +                E  N ++ ++ KP  +  W    +++ 
Sbjct: 11696 RPGPC--QNLKVTNVTKENCTISWENPLDNGGSEITNFIVEYR-KPNQK-GWSIVASDVT 11751

Query: 889   KNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETAS--IDIQIIDRPGPPQIVK 946
             K  I       +   F   AE         +V V   +ET +  + I  IDRPG P+ + 
Sbjct: 11752 KRLIKANLLANNEYYFRVCAEN--------KVGVGPTIETKTPILAINPIDRPGEPENLH 11803

Query: 947   IEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGN 1006
             I D     V L W  P  DG +    Y +++  K S +W  V +   + +  + +  + N
Sbjct: 11804 IADKGKTFVYLKWRRPDYDGGSPNLSYHVERRLKGSDDWERVHKGSIKETHYMVDRCVEN 11863

Query: 1007  EYY-FRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYA 1065
             + Y FRV ++N  G S+   +  E  V+  D               + P+    L     
Sbjct: 11864 QIYEFRVQTKNEGGESD--WVKTEEVVVKED--------------LQKPVLDLKLSGVLT 11907

Query: 1066  I-AGYNATLNCSVRGNPKPKITWMKNKVA--IVDDPRYRMFSNQGVCTLEIRKPSPYDGG 1122
             + AG    L   VRG P P++ W K+K A  +   PR ++ +        + K    DGG
Sbjct: 11908 VKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKAKRSDGG 11967

Query: 1123  TYCCKAVNDLGT 1134
              Y   A N  G+
Sbjct: 11968 KYVVTATNTAGS 11979



 Score =  112 bits (280), Expect = 2e-24
 Identities = 102/419 (24%), Positives = 166/419 (39%), Gaps = 35/419 (8%)

Query: 744   SPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFT 803
             SP   L  D +   +V + WRPP   G A + GY+LE        W   +   +  T   
Sbjct: 23925 SPEGPLEYDDIQVRSVRVSWRPPADDGGADILGYILERREVPKAAWYTIDSR-VRGTSLV 23983

Query: 804   ITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEA 863
             + GL  + +   RV A N  G S+P    +P+  K  + PP+   P       +     +
Sbjct: 23984 VKGLKENVEYHFRVSAENQFGISKPLKSEEPVTPKTPLNPPE---PPSNPPEVLDVTKSS 24040

Query: 864   VNLVIPFQGKPRPELTWKKDGAEIDKNQIN----IRNSETD-TIIFIRKAERSHSGKYDL 918
             V+L      +P+ +   +  G  I++ + +    +R+++T  T             +Y  
Sbjct: 24041 VSLS---WSRPKDDGGSRVTGYYIERKETSTDKWVRHNKTQITTTMYTVTGLVPDAEYQF 24097

Query: 919   QVKVDKFV---ETASIDIQII-----DRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAI 970
             ++     V   ET+     ++     D+P  P  ++I  +  ++V L W  P+ DG   I
Sbjct: 24098 RIIAQNDVGLSETSPASEPVVCKDPFDKPSQPGELEILSISKDSVTLQWEKPECDGGKEI 24157

Query: 971   TGYTIQKADKKSMEWF-TVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKE 1029
              GY ++        W  +  E       TI  L+   EY FRVF+EN  GLS        
Sbjct: 24158 LGYWVEYRQSGDSAWKKSNKERIKDKQFTIGGLLEATEYEFRVFAENETGLSRPRRTAMS 24217

Query: 1030  SAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMK 1089
                    G              EAP   + + +     G  A L+C + G P P I W +
Sbjct: 24218 IKTKLTSG--------------EAPGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYR 24263

Query: 1090  NKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVKVIAQ 1148
                 ++   +Y+M S+    TL +      D G Y C A N++G VE   KL ++   Q
Sbjct: 24264 FGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQATPQ 24322



 Score =  111 bits (277), Expect = 4e-24
 Identities = 171/794 (21%), Positives = 305/794 (38%), Gaps = 96/794 (12%)

Query: 381   GERVELECEVSEDDA-NVKWFKNGEEIIPGPKSRYRIRVEGKKHI--LIIEGATKADAAE 437
             G  V+L   +S   A  ++W+K+ +E+    ++   + VE    +  ++I+ A + ++  
Sbjct: 20582 GTSVKLRAGISGKPAPTIEWYKDDKEL----QTNALVCVENTTDLASILIKDADRLNSGC 20637

Query: 438   YSVMTTGGQSSAKLSVDL----KPLKILTPLTDQTVNLGKEICLKCEISENIPGKWTKNG 493
             Y +       SA  ++ +    KP     P+  +TV   K   L    +++   K T   
Sbjct: 20638 YELKLRNAMGSASATIRVQILDKPGPPGGPIEFKTVTAEKITLLWRPPADDGGAKITHYI 20697

Query: 494   LPVQESDRLK-VVHKGRIHKLVIANALTEDEGDYVF---APDAYNVTLPAKVH-VIDPPK 548
             +  +E+ R+   +    + + +I         +Y+F   A + Y +  P +   V+    
Sbjct: 20698 VEKRETSRVVWSMVSEHLEECIITTTKIIKGNEYIFRVRAVNKYGIGEPLESDSVVAKNA 20757

Query: 549   IILDGLDADNTVTVIAGNKLRL----EIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYP 604
              +  G      VT I  N + +     I   G         + DK  + G  ++  E+  
Sbjct: 20758 FVTPGPPGIPEVTKITKNSMTVVWSRPIADGGSDISGYFLEKRDKKSL-GWFKVLKETIR 20816

Query: 605   DSSTLVIDIAERDDSGVYHINLKNEAGE---AHASIKVKVVDFPDPPVAPTVTEVGDDW- 660
             D+   V  + E  D   Y +   N AG+   +  S   K  D  DPP  P    + D   
Sbjct: 20817 DTRQKVTGLTENSDYQ-YRVCAVNAAGQGPFSEPSEFYKAADPIDPPGPPAKIRIADSTK 20875

Query: 661   --CIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNF-DLCKETTFEPKKMIEGVAYEV 717
                 + W  P YDGGS + GY +E ++ +   W  ++     + T +    +  GV Y  
Sbjct: 20876 SSITLGWSKPVYDGGSAVTGYVVEIRQGEEEEWTTVSTKGEVRTTEYVVSNLKPGVNYYF 20935

Query: 718   RIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGY 777
             R+ AVN  G  +P   + P     +   P +       D  V +R      I  AG D  
Sbjct: 20936 RVSAVNCAGQGEPIEMNEPVQAKDILEAPEI-------DLDVALR---TSVIAKAGEDVQ 20985

Query: 778   VLEYCFEG----TEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVN-----------A 822
             VL   F+G    T  W    K+L    +++I    TD+   + +  V             
Sbjct: 20986 VL-IPFKGRPPPTVTWRKDEKNLGSDARYSIEN--TDSSSLLTIPQVTRNDTGKYILTIE 21042

Query: 823   AGASEPKYYSQPILVKEIIEP---PKIRIPRHLKQTYIRRVGE---------AVNLVIPF 870
              G  EPK  S  + VK +  P    K+++ +H+ +  +  + +          +N VI  
Sbjct: 21043 NGVGEPK--SSTVSVKVLDTPAACQKLQV-KHVSRGTVTLLWDPPLIDGGSPIINYVI-- 21097

Query: 871   QGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETAS 930
             + +   + TW     +       + +    T  F R    +  G       + +  ET  
Sbjct: 21098 EKRDATKRTWSVVSHKCSSTSFKLIDLSEKTPFFFRVLAENEIG-------IGEPCETTE 21150

Query: 931   IDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIE 990
               ++  + P P + + ++D    +V L+WT P  DG + IT Y +++  K    W +   
Sbjct: 21151 -PVKAAEVPAPIRDLSMKDSTKTSVILSWTKPDFDGGSVITEYVVERKGKGEQTW-SHAG 21208

Query: 991   HYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDF 1050
                     +++L   +   FRVF++N  GLS+  T+          G I    V E    
Sbjct: 21209 ISKTCEIEVSQLKEQSVLEFRVFAKNEKGLSDPVTI----------GPI---TVKELIIT 21255

Query: 1051  SEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCT 1110
              E  +   P        G+N  L    +G PKP I+W+K+ + + +    R    +   T
Sbjct: 21256 PEVDLSDIPGAQVTVRIGHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKIT 21315

Query: 1111  LEIRKPSPYDGGTY 1124
             L I+      GG Y
Sbjct: 21316 LSIKNAKKEHGGKY 21329



 Score =  110 bits (276), Expect = 6e-24
 Identities = 178/826 (21%), Positives = 314/826 (38%), Gaps = 118/826 (14%)

Query: 377   TAYCGERVELECEVS-EDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADA 435
             T   G  + L+  V  + +  + W K  +E+    K    ++  GK+   +I+   ++D+
Sbjct: 22753 TIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEK--VSLQYTGKRATAVIKFCDRSDS 22810

Query: 436   AEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCEISENIP-----GKWT 490
              +Y++       +  +SV +K L    P    TV+   +   KC ++ ++P      + T
Sbjct: 22811 GKYTLTVKNASGTKAVSVMVKVLDSPGPCGKLTVSRVTQE--KCTLAWSLPQEDGGAEIT 22868

Query: 491   KNGLPVQESDRLK-VVHKGRIHKLVIANALTEDEGDYVF---APDAYNVTLPAKVH---- 542
                +  +E+ RL  V+ +G    L           +Y+F   A + Y   +P +      
Sbjct: 22869 HYIVERRETSRLNWVIVEGECPTLSYVVTRLIKNNEYIFRVRAVNKYGPGVPVESEPIVA 22928

Query: 543   ----VIDPPKIILDGLDADNTVTVI--------AGNKLRLEIPISGEPPPKAMWSRGDKA 590
                  I  P  I + +       +I         GN++   + +         W+R +K 
Sbjct: 22929 RNSFTIPSPPGIPEEVGTGKEHIIIQWTKPESDGGNEISNYL-VDKREKKSLRWTRVNKD 22987

Query: 591   IMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDF-PDPPV 649
              +    R++  S  +       +   + +G       +E  EA   I  +   + P PP 
Sbjct: 22988 YVVYDTRLKVTSLMEGCDYQFRVTAVNAAG------NSEPSEASNFISCREPSYTPGPPS 23041

Query: 650   APTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLC-KETTFEPKK 708
             AP V +       + W  P YDGG+ I+GY +E ++K + +W R++ +   + T F    
Sbjct: 23042 APRVVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDTDQWYRVHTNATIRNTEFTVPD 23101

Query: 709   MIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTT---------- 758
             +  G  Y  R+ AVN  G+S+ S       P+     P L   D +  T           
Sbjct: 23102 LKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEIPDLELADDLKKTVTIRAGASLRL 23161

Query: 759   -VTMRWRPPDHI--GAAGLDGYVLEYCFEGTEDW---IVANKDLIDKTKFTITGLPTDAK 812
              V++  RPP  I     G+D        + TE +   IV   +  D  K+TI        
Sbjct: 23162 MVSVSGRPPPVITWSKQGID-LASRAIIDTTESYSLLIVDKVNRYDAGKYTI-------- 23212

Query: 813   IFVRVKAVNAAGASEPKYYSQPILVKEIIEP---PKIRIPRHLKQTY-----IRRV--GE 862
                  +A N +G       S  +LVK    P   P +++    + +      I  +  G 
Sbjct: 23213 -----EAENQSGKK-----SATVLVKVYDTPGPCPSVKVKEVSRDSVTITWEIPTIDGGA 23262

Query: 863   AVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKV 922
              VN  I  + +      +K    +  K    I      T+ + R    +  G       +
Sbjct: 23263 PVNNYI-VEKREAAMRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYG-------I 23314

Query: 923   DKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKS 982
              +  ET+   + + + P  P  +++ DV    V L W  P  DG + +TGY ++     +
Sbjct: 23315 GEPCETSDA-VLVSEVPLVPAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGT 23373

Query: 983   MEWF-------TVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIAR 1035
               W        TV+EH      T+T L  G +Y FR+ ++N  G+SE       +AV  +
Sbjct: 23374 ERWMKVVTLKPTVLEH------TVTSLNEGEQYLFRIRAQNEKGVSEPRETV--TAVTVQ 23425

Query: 1036  DGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIV 1095
             D ++         D S     T P    +  AG    L   + G P P  +W      + 
Sbjct: 23426 DLRVLPT-----IDLS-----TMPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLR 23475

Query: 1096  DDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKL 1141
             +  R  + ++  V  L IR+ +  D G Y  +  N  GT     K+
Sbjct: 23476 ESERVTVETHTKVAKLTIRETTIRDTGEYTLELKNVTGTTSETIKV 23521



 Score =  110 bits (275), Expect = 8e-24
 Identities = 108/438 (24%), Positives = 170/438 (38%), Gaps = 62/438 (14%)

Query: 727   ISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGT 786
             + KP +P+ P            +  D VT   +T++W PP   G + +  Y+LE      
Sbjct: 13768 VGKPGIPTGP------------IKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDSVN 13815

Query: 787   EDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGA-----SEPKYYSQPILVKEII 841
               W+      + KT F +T L    +   RV A N  G      SEP     P  V +  
Sbjct: 13816 NKWVTC-ASAVQKTTFRVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVPDAP 13874

Query: 842   EPPKIRIPRH----LKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNS 897
              PP I   RH    L  T  ++ G +       + K R  L WK+     +K  I +R+ 
Sbjct: 13875 PPPNIVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKR----ANKTPIRMRDF 13930

Query: 898   ETDTIIFIRKAERSHSGKYDLQVKVDKFVETAS--------IDIQIIDRPGPPQIVKIED 949
             +   +        +   +Y+ +V                  + +  ID PG P+++ I  
Sbjct: 13931 KVTGL--------TEGLEYEFRVMAINLAGVGKPSLPSEPVVALDPIDPPGKPEVINITR 13982

Query: 950   VWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIE-HYHRTSATITELVIGNEY 1008
                 +V L WT PK DG   +TGY ++K D  S  W      +    + T+T+LV G +Y
Sbjct: 13983 ---NSVTLIWTEPKYDGGHKLTGYIVEKRDLPSKSWMKANHVNVPECAFTVTDLVEGGKY 14039

Query: 1009  YFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAI-- 1066
              FR+ ++N  G     + + E+ +I +D            ++    +   P +       
Sbjct: 14040 EFRIRAKNTAGAISAPSESTET-IICKD------------EYEAPTIVLDPTIKDGLTIK 14086

Query: 1067  AGYNATLNC-SVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYC 1125
             AG    LN  S+ G P PK +W K    I      ++ S      L I+  +  D G Y 
Sbjct: 14087 AGDTIVLNAISILGKPLPKSSWSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGEYT 14146

Query: 1126  CKAVNDLGTVEIECKLEV 1143
               A N  GT     K+ V
Sbjct: 14147 ITATNPFGTKVEHVKVTV 14164



 Score =  109 bits (273), Expect = 1e-23
 Identities = 118/440 (26%), Positives = 185/440 (42%), Gaps = 69/440 (15%)

Query: 622   YHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFI 681
             Y +N    +  + AS  +   +  D P  P VT+V      + W  PAYDGGS ++GY I
Sbjct: 22611 YALNAAGVSKASEASRPIMAQNPVDAPGRPEVTDVTRSTVSLIWSAPAYDGGSKVVGYII 22670

Query: 682   ERK---KKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIG-ISKPSMPSRPF 737
             ERK   +    RW++ N+ +  +  F    + EG  YE R+ A NA G ISK S  + P 
Sbjct: 22671 ERKPVSEVGDGRWLKCNYTIVSDNFFTVTALSEGDTYEFRVLAKNAAGVISKGSESTGPV 22730

Query: 738   VPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTED----WIVAN 793
                   +PP       +    VT+R         AG D  VL+    G  +    W   +
Sbjct: 22731 TCRDEYAPPKAELDARLHGDLVTIR---------AGSD-LVLDAAVGGKPEPKIIWTKGD 22780

Query: 794   K--DLIDKTKFTITGLPTDAKIFVRVKA------VNAAGASEPKYYSQPILVKEIIEPPK 845
             K  DL +K     TG    A I    ++      +    AS  K  S  ++VK +  P  
Sbjct: 22781 KELDLCEKVSLQYTGKRATAVIKFCDRSDSGKYTLTVKNASGTKAVS--VMVKVLDSP-- 22836

Query: 846   IRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTW----KKDGAEI--------DKNQIN 893
                            G    L +    + +  L W    +  GAEI        + +++N
Sbjct: 22837 ---------------GPCGKLTVSRVTQEKCTLAWSLPQEDGGAEITHYIVERRETSRLN 22881

Query: 894   --IRNSETDTIIFIRKAERSHSGKYDLQVK-VDKFVETASIDIQ-IIDR-----PGPPQI 944
               I   E  T+ ++       + +Y  +V+ V+K+     ++ + I+ R     P PP I
Sbjct: 22882 WVIVEGECPTLSYV-VTRLIKNNEYIFRVRAVNKYGPGVPVESEPIVARNSFTIPSPPGI 22940

Query: 945   VKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHY--HRTSATITEL 1002
              +      E++ + WT P+ DG   I+ Y + K +KKS+ W  V + Y  + T   +T L
Sbjct: 22941 PEEVGTGKEHIIIQWTKPESDGGNEISNYLVDKREKKSLRWTRVNKDYVVYDTRLKVTSL 23000

Query: 1003  VIGNEYYFRVFSENMCGLSE 1022
             + G +Y FRV + N  G SE
Sbjct: 23001 MEGCDYQFRVTAVNAAGNSE 23020



 Score =  107 bits (268), Expect = 5e-23
 Identities = 123/468 (26%), Positives = 198/468 (42%), Gaps = 56/468 (11%)

Query: 221  RREVKQQEEE---PQVDVWELLKNAKPSEYEKIAFQYGITDLRGMLKRLKRMRREEKKSA 277
            R + K++ EE     +   EL    K   YE++  +        +L   K +  EEKK+ 
Sbjct: 1952 RSKFKRRTEEGYYEAITAVELKSRKKDESYEELLRK----TKDELLHWTKELTEEEKKAL 2007

Query: 278  AF-AKILDPAYQVDK-----------------------GGRVRFVVELAD-PKLEVKWYK 312
            A   KI  P ++ DK                       G    F V +   P  E +WYK
Sbjct: 2008 AEEGKITIPTFKPDKIELSPSMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYK 2067

Query: 313  NGQEIRPSTK---YIFEHKGCQRILFINNCQMTDDSEYYV----TAGDEKCSTELFVREP 365
            NG +I  S +   Y  E   C+  L I +    D +   V     AG+      L V+  
Sbjct: 2068 NGVKIERSDRIYWYWPEDNVCE--LVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQAK 2125

Query: 366  PIMV-TKQLEDTTAYCGERV-ELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKH 423
             ++  T++L+D  A   + +   ECE SE    VKW+K+G E+  G K  YR+  + K H
Sbjct: 2126 QLITFTQELQDVVAKEKDTMATFECETSEPFVKVKWYKDGMEVHEGDK--YRMHSDRKVH 2183

Query: 424  ILIIEGATKADAAEYS---VMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCE 480
             L I     +DA +YS   V     +++AKL V+   ++ +  L D  V       L+C 
Sbjct: 2184 FLSILTIDTSDAEDYSCVLVEDENVKTTAKLIVEGAVVEFVKELQDIEVPESYSGELECI 2243

Query: 481  IS-ENIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPA 539
            +S ENI GKW  N + ++ + +  +  +     L + +   ED+G+Y F  D    T   
Sbjct: 2244 VSPENIEGKWYHNDVELKSNGKYTITSRRGRQNLTVKDVTKEDQGEYSFVIDGKKTT--C 2301

Query: 540  KVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIR 599
            K+ +   P  IL GL       V  G+ ++LE+ +S E   + +W + D   ++ S R+ 
Sbjct: 2302 KLKMKPRPIAILQGLSDQK---VCEGDIVQLEVKVSLE-SVEGVWMK-DGQEVQPSDRVH 2356

Query: 600  TESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDP 647
                  S  L+I+   ++D+G Y   +          + V  VD   P
Sbjct: 2357 IVIDKQSHMLLIEDMTKEDAGNYSFTIPALGLSTSGRVSVYSVDVITP 2404



 Score =  106 bits (265), Expect = 1e-22
 Identities = 127/538 (23%), Positives = 203/538 (37%), Gaps = 68/538 (12%)

Query: 645  PDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTF 704
            P PP  P V +       + W+PPA DGGSPI GY +E +++ ++ W R+N      TT 
Sbjct: 9400 PGPPSCPEVKDKTKSSISLGWKPPAKDGGSPIKGYIVEMQEEGTTDWKRVNEPDKLITTC 9459

Query: 705  E--PKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTV--- 759
            E     + E   Y  R+ AVN  G S+PS  +       +   P +       D  V   
Sbjct: 9460 ECVVPNLKELRKYRFRVKAVNEAGESEPSDTTGEIPATDIQEEPEVFIDIGAQDCLVCKA 9519

Query: 760  --------TMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDA 811
                     ++ RP     +   DG   +   +G  D I  +  L      ++  +P   
Sbjct: 9520 GSQIRIPAVIKGRPTPK-SSWEFDGKAKKAMKDGVHD-IPEDAQLETAENSSVIIIPECK 9577

Query: 812  KIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIP-- 869
            +      ++ A   +  K  +  + V ++  PPK      LK + I R    ++  +P  
Sbjct: 9578 RSHTGKYSITAKNKAGQKTANCRVKVMDVPGPPK-----DLKVSDITRGSCRLSWKMPDD 9632

Query: 870  ----------FQGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIR-KAERSHSGKYDL 918
                       + +      W K   +       + +  ++   F R +AE     ++ +
Sbjct: 9633 DGGDRIKGYVIEKRTIDGKAWTKVNPDCGSTTFVVPDLLSEQQYFFRVRAEN----RFGI 9688

Query: 919  QVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQ-- 976
               V+    T + D   I  P PP  +KI  +    V L+W PPK+DG + +T Y ++  
Sbjct: 9689 GPPVETIQRTTARDP--IYPPDPPIKLKIGLITKNTVHLSWKPPKNDGGSPVTHYIVECL 9746

Query: 977  ---KADKKSMEWFTVIEH-YHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAV 1032
                   K   W    +        T+ +LV G EY FRV + N  G+S+ +        
Sbjct: 9747 AWDPTGTKKEAWRQCNKRDVEELQFTVEDLVEGGEYEFRVKAVNAAGVSKPSATVGPCDC 9806

Query: 1033 IARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMK--- 1089
               D      P  +  +F E               G N  +   ++G P P +TW K   
Sbjct: 9807 QRPD----MPPSIDLKEFMEVE------------EGTNVNIVAKIKGVPFPTLTWFKAPP 9850

Query: 1090 ----NKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1143
                NK  ++ D           CTL I +    D G Y   AVN+LGT   E +L V
Sbjct: 9851 KKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDTGLYTITAVNNLGTASKEMRLNV 9908



 Score =  105 bits (263), Expect = 2e-22
 Identities = 101/375 (26%), Positives = 158/375 (42%), Gaps = 21/375 (5%)

Query: 288  QVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEY 347
            +V +G  V+  V+++   +E  W K+GQE++PS +          +L I +    D   Y
Sbjct: 2320 KVCEGDIVQLEVKVSLESVEGVWMKDGQEVQPSDRVHIVIDKQSHMLLIEDMTKEDAGNY 2379

Query: 348  YVTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDD-ANVKWFKNGEEI 406
              T      ST   V    + V   L+D     G +  LEC+VS  D  +VKW+ N E+I
Sbjct: 2380 SFTIPALGLSTSGRVSVYSVDVITPLKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQI 2439

Query: 407  IPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTD 466
               P  R +  V+G K  L+I     +D   Y ++    +++  LSV+   +KI+  L D
Sbjct: 2440 --KPDDRVQAIVKGTKQRLVINRTHASDEGPYKLIVGRVETNCNLSVE--KIKIIRGLRD 2495

Query: 467  QTVNLGKEICLKCEISEN-IPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGD 525
             T    + +  + E+S + I   W      ++ S + K+   G+I+KL + N + +DEG 
Sbjct: 2496 LTCTETQNVVFEVELSHSGIDVLWNFKDKEIKPSSKYKIEAHGKIYKLTVLNMMKDDEGK 2555

Query: 526  YVF--APDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAM 583
            Y F    +  +  L      I  P         D TV          E+     P  K  
Sbjct: 2556 YTFYAGENMTSGKLTVAGGAISKPL-------TDQTVAESQEAVFECEV---ANPDSKGE 2605

Query: 584  WSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVD 643
            W R  K  +  +  IR+ES      L+I   + DD G Y    K    +  A +KV+ V 
Sbjct: 2606 WLRDGKH-LPLTNNIRSESDGHKRRLIIAATKLDDIGEY--TYKVATSKTSAKLKVEAVK 2662

Query: 644  FPDPPVAPTVTEVGD 658
                    TVTE  D
Sbjct: 2663 IKKTLKNLTVTETQD 2677



 Score =  102 bits (255), Expect = 2e-21
 Identities = 103/389 (26%), Positives = 171/389 (43%), Gaps = 15/389 (3%)

Query: 273  EKKSAAFAKILDPAYQVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHK-GCQ 331
            E+    F K L+    V KG  +    EL + + +V W K+G+ +      I     G  
Sbjct: 4903 EELPVRFVKTLEEEVTVVKGQPLYLSCEL-NKERDVVWRKDGKIVVEKPGRIVPGVIGLM 4961

Query: 332  RILFINNCQMTDDSEYYVT---AGDEKCSTELFVREP-PIMVTKQLEDTTAYCGERVELE 387
            R L IN+   TD   Y VT   A + +CS+ + V E     + K + D            
Sbjct: 4962 RALTINDADDTDAGTYTVTVENANNLECSSCVKVVEVIRDWLVKPIRDQHVKPKGTAIFA 5021

Query: 388  CEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQS 447
            C++++D  N+KWFK  +EI   P  +  I  +G    L I+ A   D AEY+V   G + 
Sbjct: 5022 CDIAKDTPNIKWFKGYDEIPAEPNDKTEILRDGNHLYLKIKNAMPEDIAEYAVEIEGKRY 5081

Query: 448  SAKLSVDLKPLKILTPLTDQTVNLGKEICLKCEISE-NIPGKWTKNGLPVQESDRLKVVH 506
             AKL++  + +++L P+ D T+   +      EISE +IPG+W   G  ++ S   ++  
Sbjct: 5082 PAKLTLGEREVELLKPIEDVTIYEKESASFDAEISEADIPGQWKLKGELLRPSPTCEIKA 5141

Query: 507  KGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGN 566
            +G    L +     +  G+ ++   A N    A   ++   +I LD       VTV    
Sbjct: 5142 EGGKRFLTLHKVKLDQAGEVLY--QALNAITTA---ILTVKEIELDFAVPLKDVTVPERR 5196

Query: 567  KLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINL 626
            + R E  ++ E     +WS+G   I++ S +    +      LVI+ ++ DD GVY   +
Sbjct: 5197 QARFECVLTRE--ANVIWSKGPD-IIKSSDKFDIIADGKKHILVINDSQFDDEGVYTAEV 5253

Query: 627  KNEAGEAHASIKVKVVDFPDPPVAPTVTE 655
            + +   A   +    + F  P    TV E
Sbjct: 5254 EGKKTSARLFVTGIRLKFMSPLEDQTVKE 5282



 Score =  102 bits (254), Expect = 2e-21
 Identities = 85/281 (30%), Positives = 121/281 (43%), Gaps = 16/281 (5%)

Query: 308  VKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTELFVREPPI 367
            V W K    I+ S K+     G + IL IN+ Q  D+  Y      +K S  LFV    +
Sbjct: 5210 VIWSKGPDIIKSSDKFDIIADGKKHILVINDSQFDDEGVYTAEVEGKKTSARLFVTGIRL 5269

Query: 368  MVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILII 427
                 LED T   GE     CE+S +  +V WFKN  ++         I  EGK H L +
Sbjct: 5270 KFMSPLEDQTVKEGETATFVCELSHEKMHVVWFKNDAKL--HTSRTVLISSEGKTHKLEM 5327

Query: 428  EGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCEISENIPG 487
            +  T  D ++         S+A+L V          L D+T     EI LKCE+S+++P 
Sbjct: 5328 KEVTLDDISQIKAQVKELSSTAQLKVLEADPYFTVKLHDKTAVEKDEITLKCEVSKDVPV 5387

Query: 488  KWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYV----FAPDAYNVTLPAKVHV 543
            KW K+G  +  S +  +   G    L I  A  +D+G+YV          NVT+ A++  
Sbjct: 5388 KWFKDGEEIVPSPKYSIKADGLRRILKIKKADLKDKGEYVCDCGTDKTKANVTVEARLIK 5447

Query: 544  IDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMW 584
            ++ P   L G      V V  G     EI +S EP     W
Sbjct: 5448 VEKP---LYG------VEVFVGETAHFEIELS-EPDVHGQW 5478



 Score =  102 bits (254), Expect = 2e-21
 Identities = 174/746 (23%), Positives = 285/746 (38%), Gaps = 121/746 (16%)

Query: 365   PPIMVTKQLEDTTAYCGERVELECEV-SEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKH 423
             P I++ +Q+   T   G+++ +E  V  +     KW K  +E++    S   +       
Sbjct: 12595 PKILMPEQI---TIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTS--SHLAVHKADSSS 12649

Query: 424   ILIIEGATKADAAEYSVMT--TGGQSSAKLSV--------------------DLKPLKIL 461
             ILII+  T+ D+  YS+    + G  + K+ V                    D   L   
Sbjct: 12650 ILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPGPPQPPFDISDIDADACSLSWH 12709

Query: 462   TPLTDQTVNLGKEICLKCEISENIPGKW-TKNGLPVQESDRLKVVHKGRIH--------K 512
              PL D   N+   I  KC++S    G W T      + S R+  +  G+ +        +
Sbjct: 12710 IPLEDGGSNITNYIVEKCDVSR---GDWVTALASVTKTSCRVGKLIPGQEYIFRVRAENR 12766

Query: 513   LVIANALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKIIL--DGLDADNTVTVIAGNKLRL 570
               I+  LT  +    F     +    A+V  ++   I +  D  D+D    +I       
Sbjct: 12767 FGISEPLTSPKMVAQFPFGVPSEPKNARVTKVNKDCIFVAWDRPDSDGGSPIIG------ 12820

Query: 571   EIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEA 630
                I  +     +W + +  +      +R+  YP +   +++  E      + I   N+A
Sbjct: 12821 -YLIERKERNSLLWVKANDTL------VRSTEYPCAG--LVEGLEYS----FRIYALNKA 12867

Query: 631   GEAHASIKVKVVDFP---DPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQ 687
             G +  S   + V      DPP  P V +V      + W  P +DGGS I+GYF+E  K  
Sbjct: 12868 GSSPPSKPTEYVTARMPVDPPGKPEVIDVTKSTVSLIWARPKHDGGSKIIGYFVEACKLP 12927

Query: 688   SSRWMRLNF--DLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSP 745
               +W+R N       +  +    + E   Y+ R  A  A+ IS PS PS P   LA   P
Sbjct: 12928 GDKWVRCNTAPHQIPQEEYTATGLEEKAQYQFRAIARTAVNISPPSEPSDPVTILAENVP 12987

Query: 746   P---------TLLTVDSVT----DTTV------TMRWRPPDHI--GAAGLDGYVLEYCFE 784
             P         +LLTV + T    D TV      T+ W+    +   A G+    ++    
Sbjct: 12988 PRIDLSVAMKSLLTVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIK-MAMQRNLC 13046

Query: 785   GTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEP----KYYSQPILVKEI 840
               E + V  KD  D T  T           +++K ++  G        K YS   ++   
Sbjct: 13047 TLELFSVNRKDSGDYT-ITAENSSGSKSATIKLKVLDKPGPPASVKINKMYSDRAMLSW- 13104

Query: 841   IEPPKIRIPRHLKQTYIRRVG-EAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSET 899
              EPP            +   G E  N ++  +   RP   W +  A +     ++     
Sbjct: 13105 -EPP------------LEDGGSEITNYIVDKRETSRPN--WAQVSATVPITSCSVEKLIE 13149

Query: 900   DTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTW 959
                   R    +  G  D       F E A I     D PG      I ++  +++ ++W
Sbjct: 13150 GHEYQFRICAENKYGVGD-----PVFTEPA-IAKNPYDPPGRCDPPVISNITKDHMTVSW 13203

Query: 960   TPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATI--TELVIGNEYYFRVFSENM 1017
              PP DDG + ITGY ++K + +++ W T +        T+  T L  G EY FRV + N 
Sbjct: 13204 KPPADDGGSPITGYLLEKRETQAVNW-TKVNRKPIIERTLKATGLQEGTEYEFRVTAINK 13262

Query: 1018  CGLSEDATMTKESAVIARDGKIYKNP 1043
              G  + +  +K  A  ARD +    P
Sbjct: 13263 AGPGKPSDASK--AAYARDPQYPPGP 13286



 Score =  101 bits (251), Expect = 5e-21
 Identities = 123/553 (22%), Positives = 204/553 (36%), Gaps = 63/553 (11%)

Query: 622   YHINLKNEAGEAHASIKVKVV---DFPDPPVAPTVTEVGDDW---CIMNWEPPAYDGGSP 675
             + +  +NE G    S+  + V   D  +PP  PT   V D       + W  P YDGG+P
Sbjct: 12163 FRVKAENEIGIGEPSLPSRPVVAKDPIEPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAP 12222

Query: 676   ILGYFIERKKKQSSR-----WMRLNFDL-CKETTFEPKKMIEGVAYEVRIFAVNAIGISK 729
             I+GY +E + K +       W R N         F    + E   YE R+ A N +GI +
Sbjct: 12223 IIGYVVEMRPKIADASPDEGWKRCNAAAQLVRKEFTVTSLDENQEYEFRVCAQNQVGIGR 12282

Query: 730   PSMPSRPFVPLAVTSPPTLLTVDSVTDTTVT-----------MRWRPPDHIG--AAGLDG 776
             P+       P  +  PP +    S+    +            +R RP   +     G+D 
Sbjct: 12283 PAELKEAIKPKEILEPPEIDLDASMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDN 12342

Query: 777   YVLEYCFEGTEDW---IVANKDLIDKTKFTITGL-PTDAK-IFVRVKAVNAAGASEPKYY 831
              V +   +  +     ++ N    D  K+++T + P   K +FV V+ ++  G       
Sbjct: 12343 VVRKGQVDLVDTMAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFVNVRVLDTPG------- 12395

Query: 832   SQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQ 891
               P+   ++ +  K     H+        G +       + +     TW     E+ K  
Sbjct: 12396 --PVSDLKVSDVTKTSC--HVSWAPPENDGGSQVTHYIVEKREADRKTWSTVTPEVKKTS 12451

Query: 892   INIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVW 951
              ++ N       + R    +  G       V   V    +    +  P PP+ +++ ++ 
Sbjct: 12452 FHVTNLVPGNEYYFRVTAVNEYGP-----GVPTDVPKPVLASDPLSEPDPPRKLEVTEMT 12506

Query: 952   GENVALTWTPPKDDGNAAITGY-TIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYF 1010
               +  L W PP  DG A I GY T  + +++  + +T        S  +T L  G +Y F
Sbjct: 12507 KNSATLAWLPPLRDGGAKIDGYITSYREEEQPADRWTEYSVVKDLSLVVTGLKEGKKYKF 12566

Query: 1011  RVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYN 1070
             RV + N  G+S           + R+ +     VYE  +    P    P   T   AG  
Sbjct: 12567 RVAARNAVGVS-----------LPREAE----GVYEAKEQLLPPKILMPEQITIK-AGKK 12610

Query: 1071  ATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVN 1130
               +   V G P P   W K +  +V      +        L I+  +  D G Y   A N
Sbjct: 12611 LRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGYYSLTAEN 12670

Query: 1131  DLGTVEIECKLEV 1143
               GT   + K+ V
Sbjct: 12671 SSGTDTQKIKVVV 12683



 Score =  100 bits (249), Expect = 8e-21
 Identities = 93/398 (23%), Positives = 157/398 (39%), Gaps = 40/398 (10%)

Query: 753   SVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAK 812
             +VT   +T+ WRPP   G A +  Y++E        W + ++ L ++   T T +    +
Sbjct: 20672 TVTAEKITLLWRPPADDGGAKITHYIVEKRETSRVVWSMVSEHL-EECIITTTKIIKGNE 20730

Query: 813   IFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQT-------YIRRVGEAVN 865
                RV+AVN  G  EP      +     + P    IP   K T       + R + +  +
Sbjct: 20731 YIFRVRAVNKYGIGEPLESDSVVAKNAFVTPGPPGIPEVTKITKNSMTVVWSRPIADGGS 20790

Query: 866   LVIPF--QGKPRPELTW---KKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQV 920
              +  +  + + +  L W    K+     + ++      +D    +     +  G +    
Sbjct: 20791 DISGYFLEKRDKKSLGWFKVLKETIRDTRQKVTGLTENSDYQYRVCAVNAAGQGPFS--- 20847

Query: 921   KVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADK 980
             +  +F + A      ID PGPP  ++I D    ++ L W+ P  DG +A+TGY ++    
Sbjct: 20848 EPSEFYKAADP----IDPPGPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVVEIRQG 20903

Query: 981   KSMEWFTVIE--HYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGK 1038
             +  EW TV        T   ++ L  G  YYFRV + N  G  E   M            
Sbjct: 20904 EEEEWTTVSTKGEVRTTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEM------------ 20951

Query: 1039  IYKNPVYEDFDFSEAPMFTQPLV---NTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIV 1095
                N   +  D  EAP     +    +  A AG +  +    +G P P +TW K++  + 
Sbjct: 20952 ---NEPVQAKDILEAPEIDLDVALRTSVIAKAGEDVQVLIPFKGRPPPTVTWRKDEKNLG 21008

Query: 1096  DDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLG 1133
              D RY + +      L I + +  D G Y     N +G
Sbjct: 21009 SDARYSIENTDSSSLLTIPQVTRNDTGKYILTIENGVG 21046



 Score = 98.6 bits (244), Expect = 3e-20
 Identities = 93/361 (25%), Positives = 149/361 (41%), Gaps = 12/361 (3%)

Query: 296  RFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEK 355
            +F  E++      +W K  QEI    ++     G +  + I +    D+++Y   A D+ 
Sbjct: 5553 KFECEVSREPKTFRWLKGTQEITGDDRFELIKDGTKHSMVIKSAAFEDEAKYMFEAEDKH 5612

Query: 356  CSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYR 415
             S +L +    +     L+D TA   E      E+S D+  VKWFKN + +         
Sbjct: 5613 TSGKLIIEGIRLKFLTPLKDVTAKEKESAVFTVELSHDNIRVKWFKNDQRL--HTTRSVS 5670

Query: 416  IRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEI 475
            ++ EGK H +  +  +  D ++  V   G  S AKL+V          L D T     E+
Sbjct: 5671 MQDEGKTHSITFKDLSIDDTSQIRVEAMGMSSEAKLTVLEGDPYFTGKLQDYTGVEKDEV 5730

Query: 476  CLKCEISE-NIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYN 534
             L+CEIS+ + P KW K+G  ++ S    +   G+   L++  AL  D G Y    D   
Sbjct: 5731 ILQCEISKADAPVKWFKDGKEIKPSKNAVIKADGKKRMLILKKALKSDIGQYTC--DCGT 5788

Query: 535  VTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWS-RGDKAIME 593
                 K+ + D    ++  L   ++V V+     R E  IS E    A W  +G+  +  
Sbjct: 5789 DKTSGKLDIEDREIKLVRPL---HSVEVMETETARFETEIS-EDDIHANWKLKGEALLQT 5844

Query: 594  GSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTV 653
                I+ E    S  LV+     D +G       N    AH  +K +V+    P    TV
Sbjct: 5845 PDCEIKEEGKIHS--LVLHNCRLDQTGGVDFQAANVKSSAHLRVKPRVIGLLRPLKDVTV 5902

Query: 654  T 654
            T
Sbjct: 5903 T 5903



 Score = 95.5 bits (236), Expect = 3e-19
 Identities = 111/492 (22%), Positives = 196/492 (39%), Gaps = 52/492 (10%)

Query: 673   GSPILGYFIERKKKQSSRWMRLNFDLCKET-TFEPKKMIEGVAYEVRIFAVNAIGISKPS 731
             G P+    + R        MR N ++  E  T   K+ +   A    I A N+ G +K  
Sbjct: 20197 GKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADAGRYEITAANSSGTTKAF 20256

Query: 732   MPSRPFVPLAVTSPPT-LLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWI 790
             +     V L    PPT  + +  +T+ +VT++W PP + G + +  Y+L      T  W 
Sbjct: 20257 IN---IVVLDRPGPPTGPVVISDITEESVTLKWEPPKYDGGSQVTNYILLKRETSTAVWT 20313

Query: 791   VANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVK---EIIEPPKIR 847
               +   + +T   +  L T  +   R+KA N  G S+    S  + VK       PP   
Sbjct: 20314 EVSAT-VARTMMKVMKLTTGEEYQFRIKAENRFGISD-HIDSACVTVKLPYTTPGPPSTP 20371

Query: 848   IPRHLKQTYI-----RRVGEAVNLVIPF--QGKPRPELTWKKDGAEIDKNQINIRNSETD 900
                ++ +  I       V    + V+ +  + K R  + W+K       N++ IR +   
Sbjct: 20372 WVTNVTRESITVGWHEPVSNGGSAVVGYHLEMKDRNSILWQK------ANKLVIRTTH-- 20423

Query: 901   TIIFIRKAERSHSGKYDLQVKVDKFVETA-----SIDIQIIDRPGPPQIVKIEDVWGENV 955
                  +    S    Y+ +V  +           S  +  ID   PP+ V+I D+   +V
Sbjct: 20424 ----FKVTTISAGLIYEFRVYAENAAGVGKPSHPSEPVLAIDACEPPRNVRITDISKNSV 20479

Query: 956   ALTWTPPKDDGNAAITGYTIQKADKKSMEWFTV-IEHYHRTSATITELVIGNEYYFRVFS 1014
             +L+W  P  DG + ITGY +++ D     W      +   T   I+ L   ++Y FRVF+
Sbjct: 20480 SLSWQQPAFDGGSKITGYIVERRDLPDGRWTKASFTNVTETQFIISGLTQNSQYEFRVFA 20539

Query: 1015  ENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAI---AGYNA 1071
              N  G     +++  S V+         P+    D    P+   PL  T  +   AG + 
Sbjct: 20540 RNAVG-----SISNPSEVVG--------PI-TCIDSYGGPVIDLPLEYTEVVKYRAGTSV 20585

Query: 1072  TLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVND 1131
              L   + G P P I W K+   +  +    + +   + ++ I+     + G Y  K  N 
Sbjct: 20586 KLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLASILIKDADRLNSGCYELKLRNA 20645

Query: 1132  LGTVEIECKLEV 1143
             +G+     ++++
Sbjct: 20646 MGSASATIRVQI 20657



 Score = 94.4 bits (233), Expect = 6e-19
 Identities = 105/462 (22%), Positives = 179/462 (38%), Gaps = 52/462 (11%)

Query: 697   DLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTD 756
             D C+E        +   A E  I  +N I + KP  P+ P            + +D VT 
Sbjct: 15904 DACREDVGHYVVKLTNSAGEA-IETLNVIVLDKPGPPTGP------------VKMDEVTA 15950

Query: 757   TTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVR 816
              ++T+ W PP + G + ++ Y++E     T  W + +   + +T      L T  +   R
Sbjct: 15951 DSITLSWGPPKYDGGSSINNYIVEKRDTSTTTWQIVSAT-VARTTIKACRLKTGCEYQFR 16009

Query: 817   VKAVNAAGAS-----EPKYYSQPILVKEIIEPPKIRIPRH--LKQTYIRRVGEAVNLVIP 869
             + A N  G S     EP     P  V      P + +     ++  +   + +  + VI 
Sbjct: 16010 IAAENRYGKSTYLNSEPTVAQYPFKVPGPPGTPVVTLSSRDSMEVQWNEPISDGGSRVIG 16069

Query: 870   F--QGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVE 927
             +  + K R  + W K    ++K  I     +T  +    + E   S +  + +     V 
Sbjct: 16070 YHLERKERNSILWVK----LNKTPIPQTKFKTTGLEEGVEYEFRVSAENIVGIGKPSKVS 16125

Query: 928   TASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFT 987
                +     D PG P+ + +      +V L W  P  DG + ITGY ++K +     W  
Sbjct: 16126 ECYVARDPCDPPGRPEAIIVTR---NSVTLQWKKPTYDGGSKITGYIVEKKELPEGRWMK 16182

Query: 988   V-IEHYHRTSATITELVIGNEYYFRVFSENMCGL-SEDATMTKESAVIARDG----KIYK 1041
                 +   T   +T LV  + Y FRV + N  G+ SE +  T   A+ ARD     +I  
Sbjct: 16183 ASFTNIIDTHFEVTGLVEDHRYEFRVIARNAAGVFSEPSEST--GAITARDEVDPPRISM 16240

Query: 1042  NPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYR 1101
             +P Y+D                   AG +  ++  + G P P I W+K    + +  R  
Sbjct: 16241 DPKYKD--------------TIVVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTARLE 16286

Query: 1102  MFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1143
             + S     +L ++     D G Y  KA N  G   +   ++V
Sbjct: 16287 IKSTDFATSLSVKDAVRVDSGNYILKAKNVAGERSVTVNVKV 16328



 Score = 94.4 bits (233), Expect = 6e-19
 Identities = 148/652 (22%), Positives = 260/652 (39%), Gaps = 111/652 (17%)

Query: 51    SRALERKDSDWTLVE---TPPGEEQAKQNANSQLSILFIEKPQGGTVKVGEDITFIAKVK 107
             S+  E K SD    E   T   E +A +  +S+  I  +   Q  TV       F  K  
Sbjct: 26514 SKISETKKSDQKTTESTVTRKTEPKAPEPISSKPVI--VTGLQDTTVSSDSVAKFAVKAT 26571

Query: 108   AEDLLRKPTIKWFK--------GKWMDLASKAGKHLQLKETFERHSRVYTFEMQIIKAKD 159
              E    +PT  W K        GK+     K G  L++ +T    S +YT  ++      
Sbjct: 26572 GEP---RPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVK------ 26622

Query: 160   NFAGNYR--CEVTYKDKFDSCSFDLEVHESTGTTPNIDIRSAFKRSGEGQEDAGELDFSG 217
             N AG+    C++T K   D+ +  +   +++  TP        K++   +E + +   S 
Sbjct: 26623 NSAGSVSSSCKLTIKAIKDTEAQKVSTQKTSEITPQ-------KKAVVQEEISQKALRSE 26675

Query: 218   LLKRREVKQQE------EEPQVDVWELLKNAKPSEYEKIAFQYGITDLRGMLKRLKRMRR 271
              +K  E K QE      E  +V + E +K +  +  EK      IT              
Sbjct: 26676 EIKMSEAKSQEKLALKEEASKVLISEEVKKSAATSLEKSIVHEEITKTS--------QAS 26727

Query: 272   EEKKSAAFAKILDPAYQVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQ 331
             EE ++ A  K       +++G R+     +A    +VKW  NG E+  S +Y +   G  
Sbjct: 26728 EEVRTHAEIKAFSTQMSINEGQRLVLKANIAGAT-DVKWVLNGVELTNSEEYRYGVSGSD 26786

Query: 332   RILFINNCQMTDDSEYYVTA----GDEKCSTELFVREPPIMVTKQLEDTTAYC------- 380
             + L I      D+      +    G  KC  +L        ++K+L D  A+        
Sbjct: 26787 QTLTIKQASHRDEGILTCISKTKEGIVKCQYDL-------TLSKELSDAPAFISQPRSQN 26839

Query: 381   ---GERVELECEVS-EDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAA 436
                G+ V   CE+S E    ++WFKN   I     S   I      + L I  A+ +D+ 
Sbjct: 26840 INEGQNVLFTCEISGEPSPEIEWFKNNLPI--SISSNVSISRSRNVYSLEIRNASVSDSG 26897

Query: 437   EYSVMTTG--GQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCEISENIPGKWTKNGL 494
             +Y++      GQ SA  S+      ++ PL ++     +E+ L+     ++ G ++   +
Sbjct: 26898 KYTIKAKNFRGQCSATASL------MVLPLVEEP---SREVVLRTSGDTSLQGSFSSQSV 26948

Query: 495   PVQESDR-----------LKVVHKGRIHKLVIANALTEDEGDYVFAPDAY----NVT--- 536
              +  S +              + + +   +   +  +  E     +  ++    N+T   
Sbjct: 26949 QMSASKQEASFSSFSSSSASSMTEMKFASMSAQSMSSMQESFVEMSSSSFMGISNMTQLE 27008

Query: 537   ------LPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKA 590
                   L A +  I PPKI  + L +D  +++  G  L +    +GEP P+  WS G + 
Sbjct: 27009 SSTSKMLKAGIRGI-PPKI--EALPSD--ISIDEGKVLTVACAFTGEPTPEVTWSCGGRK 27063

Query: 591   I-MEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKV 641
             I  +  GR   E+  D +TL+I   ++ D G+Y ++L NE G   A++ + +
Sbjct: 27064 IHSQEQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHI 27115



 Score = 93.2 bits (230), Expect = 1e-18
 Identities = 201/953 (21%), Positives = 329/953 (34%), Gaps = 190/953 (19%)

Query: 284   DPAYQVDKGGRVRFVVEL-ADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMT 342
             D  Y   +    R  + +   P   V W K    +   T+   E       L + +CQ +
Sbjct: 13684 DLCYLAKENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKS 13743

Query: 343   DDSEYYVT----AGDEKCSTELFVREPPIMVTKQL--EDTTAYC------------GERV 384
             D  +Y +T    AG ++ +  + V   P + T  +  ++ TA              G  +
Sbjct: 13744 DAGKYTITLKNVAGTKEGTISIKVVGKPGIPTGPIKFDEVTAEAMTLKWAPPKDDGGSEI 13803

Query: 385   ELECEVSEDDANVKWFKNGEEIIPGPKSRYRI-----------RVEGKKHILIIEGATKA 433
                     D  N KW      +    K+ +R+           RV  +    + EG    
Sbjct: 13804 TNYILEKRDSVNNKWVTCASAV---QKTTFRVTRLHEGMEYTFRVSAENKYGVGEGLKSE 13860

Query: 434   DAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEIC-LKCEISENIPGKWTK- 491
                                VD++   +    TD     G  I     E  E     W + 
Sbjct: 13861 PIVARHPFDVPDAPPPPNIVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRA 13920

Query: 492   NGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKIIL 551
             N  P++  D  KV              LTE   +Y F   A N+    K  +   P + L
Sbjct: 13921 NKTPIRMRD-FKVT------------GLTEGL-EYEFRVMAINLAGVGKPSLPSEPVVAL 13966

Query: 552   DGLDAD----------NTVTVI-------AGNKLRLEIPISGEPPPKAMWSRGDKAIMEG 594
             D +D            N+VT+I        G+KL   I    + P K+ W + +      
Sbjct: 13967 DPIDPPGKPEVINITRNSVTLIWTEPKYDGGHKLTGYIVEKRDLPSKS-WMKANHV---- 14021

Query: 595   SGRIRTESYPDSSTLVIDIAERDDSGVYH--INLKNEAGEAHA-SIKVKVVDFPDPPVAP 651
                    + P+ +  V D+ E    G Y   I  KN AG   A S   + +   D   AP
Sbjct: 14022 -------NVPECAFTVTDLVE---GGKYEFRIRAKNTAGAISAPSESTETIICKDEYEAP 14071

Query: 652   TVTEVGDDWCIMNWEPPAYDG-----GSPIL--GYFIERKKKQSSRWMRLNFDL----CK 700
             T+            +P   DG     G  I+     I  K    S W +   D+      
Sbjct: 14072 TIV----------LDPTIKDGLTIKAGDTIVLNAISILGKPLPKSSWSKAGKDIRPSDIT 14121

Query: 701   ETTFEPKKMIEGVAYEVR-------IFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDS 753
             + T  P   +  + Y  R       I A N  G     +       L V  PP  + + +
Sbjct: 14122 QITSTPTSSMLTIKYATRKDAGEYTITATNPFGTKVEHVK---VTVLDVPGPPGPVEISN 14178

Query: 754   VTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKI 813
             V+    T+ W PP   G + +  Y+LE        W V ++D I   +   T L    + 
Sbjct: 14179 VSAEKATLTWTPPLEDGGSPIKSYILEKRETSRLLWTVVSED-IQSCRHVATKLIQGNEY 14237

Query: 814   FVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGK 873
               RV AVN  G  EP   S+P+ + +   PP                G      +    K
Sbjct: 14238 IFRVSAVNHYGKGEP-VQSEPVKMVDRFGPP----------------GPPEKPEVSNVTK 14280

Query: 874   PRPELTWKKD----GAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETA 929
                 ++WK+     G+EI    +  R  E  ++ ++R  +   S   DL+ KV    E +
Sbjct: 14281 NTATVSWKRPVDDGGSEITGYHVERR--EKKSLRWVRAIKTPVS---DLRCKVTGLQEGS 14335

Query: 930   SIDIQIIDR-----------------------PGPPQIVKIEDVWGENVALTWTPPKDDG 966
             + + ++                          PGPP    + D   ++ +L W  P  DG
Sbjct: 14336 TYEFRVSAENRAGIGPPSEASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLAWGKPHYDG 14395

Query: 967   NAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGN-----EYYFRVFSENMCGLS 1021
                ITGY ++        W   I+    T+  IT+ V+ +     +Y FR+ + N  G+ 
Sbjct: 14396 GLEITGYVVEHQKVGDEAW---IKDTTGTALRITQFVVPDLQTKEKYNFRISAINDAGVG 14452

Query: 1022  EDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAI-AGYNATLNCSVRGN 1080
             E A +         D +I +  +  DF+          L  T  + AG +  +   ++G 
Sbjct: 14453 EPAVIP--------DVEIVEREMAPDFELDAE------LRRTLVVRAGLSIRIFVPIKGR 14498

Query: 1081  PKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLG 1133
             P P++TW K+ + + +  R  + + +    L I + + YD G +     N  G
Sbjct: 14499 PAPEVTWTKDNINLKN--RANIENTESFTLLIIPECNRYDTGKFVMTIENPAG 14549



 Score = 93.2 bits (230), Expect = 1e-18
 Identities = 127/584 (21%), Positives = 221/584 (37%), Gaps = 94/584 (16%)

Query: 606   SSTLVIDIAERDDSGV--YHINLKNEAGEAH----ASIKVKV------VDFPDPPVAPTV 653
             S T  I++++  +  V  + +  KNE G +       I VK       VD  D P A   
Sbjct: 21210 SKTCEIEVSQLKEQSVLEFRVFAKNEKGLSDPVTIGPITVKELIITPEVDLSDIPGAQVT 21269

Query: 654   TEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKET-TFEPKKMIEG 712
               +G +   ++ E P      P + +  +    + S ++R +    K T + +  K   G
Sbjct: 21270 VRIGHN---VHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHG 21326

Query: 713   VAYEVRI--------FAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWR 764
               Y V +          +  I +  PS P  P            +  D +   +V + W 
Sbjct: 21327 GKYTVILDNAVCRIAVPITVITLGPPSKPKGP------------IRFDEIKADSVILSWD 21374

Query: 765   PPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAG 824
              P+  G   +  Y +E       +W +     + +T F +  L  DA+   RV+A N  G
Sbjct: 21375 VPEDNGGGEITCYSIEKRETSQTNWKMVCSS-VARTTFKVPNLVKDAEYQFRVRAENRYG 21433

Query: 825   ASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKD- 883
              S      QP++   I+   + RIP           G+ V   +   G     LTW    
Sbjct: 21434 VS------QPLVSSIIVAKHQFRIPGP--------PGKPVIYNVTSDGM---SLTWDAPV 21476

Query: 884   ---GAEIDKNQINIRNSETDTIIFIRKAERSHSGK------------YDLQVKVDKFVET 928
                G+E+     ++   E ++I++ +      SG+            Y  +V  +     
Sbjct: 21477 YDGGSEV--TGFHVEKKERNSILWQKVNTSPISGREYRATGLVEGLDYQFRVYAENSAGL 21534

Query: 929   AS--------IDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADK 980
             +S        + +  +D PG P  +   DV  E + L W PP  DG + I GY+I+K   
Sbjct: 21535 SSPSDPSKFTLAVSPVDPPGTPDYI---DVTRETITLKWNPPLRDGGSKIVGYSIEKRQG 21591

Query: 981   KSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIY 1040
                              T+T L  G+ Y FR+ + N  G     + +    ++ RD  + 
Sbjct: 21592 NERWVRCNFTDVSECQYTVTGLSPGDRYEFRIIARNAVGTISPPSQSS-GIIMTRDENV- 21649

Query: 1041  KNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRY 1100
               P   +F     P +   L+     +G +  +   V+G P P++TW K+ V I      
Sbjct: 21650 --PPIVEF----GPEYFDGLIIK---SGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNM 21700

Query: 1101  RMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVK 1144
              +    G  +L +R  +    G Y  +A N  G+ + E K++V+
Sbjct: 21701 EITDVLGSTSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQ 21744



 Score = 92.8 bits (229), Expect = 2e-18
 Identities = 113/454 (24%), Positives = 172/454 (37%), Gaps = 74/454 (16%)

Query: 718   RIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGY 777
             R  AVN   + KP  P+ P            L ++ +T    ++ W  P   G A +D Y
Sbjct: 19566 RSVAVNCKVLDKPGPPAGP------------LEINGLTAEKCSLSWGRPQEDGGADIDYY 19613

Query: 778   VLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILV 837
             ++E        W +   +L   T   +T L    +   RV  VN  G  EP    + + +
Sbjct: 19614 IVEKRETSHLAWTICEGEL-QMTSCKVTKLLKGNEYIFRVTGVNKYGVGEPL---ESVAI 19669

Query: 838   KEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNS 897
             K +        P  L+ T + +  E++ L        RPE      G+EI    I  R  
Sbjct: 19670 KALDPFTVPSPPTSLEITSVTK--ESMTLCWS-----RPE---SDGGSEISGYIIERR-- 19717

Query: 898   ETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQI---------------------- 935
             E +++ ++R  ++     YDL+VK     E    + ++                      
Sbjct: 19718 EKNSLRWVRVNKKP---VYDLRVKSTGLREGCEYEYRVYAENAAGLSLPSETSPLIRAED 19774

Query: 936   -IDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHR 994
              +  P PP   KI D     + + W  P  DG A ITGYT++       +W T I+    
Sbjct: 19775 PVFLPSPPSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEYKKSDDTDWKTSIQSLRG 19834

Query: 995   TSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAP 1054
             T  TI+ L  G EY FRV S N  G S+ +  +        D +I K    E     ++ 
Sbjct: 19835 TEYTISGLTTGAEYVFRVKSVNKVGASDPSDSS--------DPQIAKEREEEPLFDIDSE 19886

Query: 1055  MFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMF--SNQGVCTLE 1112
             M    +V     AG + T+    RG P P + W K       D R R +  +     +L 
Sbjct: 19887 MRKTLIVK----AGASFTMTVPFRGRPVPNVLWSKPDT----DLRTRAYVDTTDSRTSLT 19938

Query: 1113  IRKPSPYDGGTYCCKAVNDLGTVEIECKLEVKVI 1146
             I   +  D G Y     N L    +   L VKV+
Sbjct: 19939 IENANRNDSGKYTLTIQNVLSAASL--TLVVKVL 19970



 Score = 92.4 bits (228), Expect = 2e-18
 Identities = 133/609 (21%), Positives = 230/609 (37%), Gaps = 111/609 (18%)

Query: 584  WSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVD 643
            WSR +K+++    +   +   +  T V  +   + +G    +  ++   AH  I      
Sbjct: 8643 WSRVNKSLLNAL-KANVDGLLEGLTYVFRVCAENAAGPGKFSPPSDPKTAHDPISP---- 8697

Query: 644  FPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETT 703
             P PP+ P VT+       + WEPPA++GG  I+GYF++++   ++ W R    + K   
Sbjct: 8698 -PGPPI-PRVTDTSSTTIELEWEPPAFNGGGEIVGYFVDKQLVGTNEWSRCTEKMIKVRQ 8755

Query: 704  FEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRW 763
            +  K++ EG  Y++R+ AVNA G   P        P+ V  P                  
Sbjct: 8756 YTVKEIREGADYKLRVSAVNAAGEGPPGETQ----PVTVAEPQ----------------- 8794

Query: 764  RPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAA 823
             PP    A  LD  V      G +  I+A K L  +    +TG P   K++ +       
Sbjct: 8795 EPP----AVELDVSVKG----GIQ--IMAGKTL--RIPAVVTGRPVPTKVWTK------- 8835

Query: 824  GASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLV--------IPFQGKPR 875
               E +     +++  +    ++ I   L++ + R V  A N          +     P 
Sbjct: 8836 --EEGELDKDRVVIDNVGTKSELIIKDALRKDHGRYVITATNSCGSKFAAARVEVFDVPG 8893

Query: 876  PELTWKKDGAEIDKNQINIRNSETDT------IIFIRKAERSHSGKYDLQVKVDKFVETA 929
            P L  K          +N  + E D        I  RK  + H+ +  ++ +  K   T 
Sbjct: 8894 PVLDLKPVVTNRKMCLLNWSDPEDDGGSEITGFIIERKDAKMHTWRQPIETERSKCDITG 8953

Query: 930  SID------------------------IQIIDRPGPP---QIVKIEDVWGENVALTWTPP 962
             ++                        I  +D  GPP   + +   +     + L W  P
Sbjct: 8954 LLEGQEYKFRVIAKNKFGCGPPVEIGPILAVDPLGPPTSPERLTYTERTKSTITLDWKEP 9013

Query: 963  KDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYY-FRVFSENMCGLS 1021
            + +G + I GY I+K      ++  V +    T++ + E +  ++ Y FRV + N  G S
Sbjct: 9014 RSNGGSPIQGYIIEKRRHDKPDFERVNKRLCPTTSFLVENLDEHQMYEFRVKAVNEIGES 9073

Query: 1022 EDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAI-AGYNATLNCSVRGN 1080
            E +       V+ +D ++               +      +T  + AG    +   V G 
Sbjct: 9074 EPSLPLN---VVIQDDEVPPT----------IKLRLSVRGDTIKVKAGEPVHIPADVTGL 9120

Query: 1081 PKPKITWMKNKVAI------VDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGT 1134
            P PKI W KN+  I      +   +  +  ++    L I K    D GTY   A N LG+
Sbjct: 9121 PMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAVREDKGTYTVTASNRLGS 9180

Query: 1135 VEIECKLEV 1143
            V     +EV
Sbjct: 9181 VFRNVHVEV 9189



 Score = 92.0 bits (227), Expect = 3e-18
 Identities = 98/417 (23%), Positives = 169/417 (40%), Gaps = 47/417 (11%)

Query: 745   PPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTI 804
             PP  + +D V+  ++T+ W PP++ G   +  Y++E     +  W + ++  + +T   I
Sbjct: 19185 PPGPIRIDEVSCDSITISWNPPEYDGGCQISNYIVEKKETTSTTWHIVSQ-AVARTSIKI 19243

Query: 805   TGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPP----KIRIPRHLKQTYIRR- 859
               L T ++   RV A N  G S     S  ++ +    PP      ++    K T +   
Sbjct: 19244 VRLTTGSEYQFRVCAENRYGKSSYSE-SSAVVAEYPFSPPGPPGTPKVVHATKSTMLVTW 19302

Query: 860   ---VGEAVNLVIPF--QGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSG 914
                V +  + VI +  + K R  + W K       N+I I     DT + +   +     
Sbjct: 19303 QVPVNDGGSRVIGYHLEYKERSSILWSK------ANKILI----ADTQMKVSGLDEGLMY 19352

Query: 915   KYDLQVKVDKFVETASIDIQII------DRPGPPQIVKIEDVWGENVALTWTPPKDDGNA 968
             +Y +  +    +   S   + +      D PG P++  I     ++V+L W+ P  DG A
Sbjct: 19353 EYRVYAENIAGIGKCSKSCEPVPARDPCDPPGQPEVTNITR---KSVSLKWSKPHYDGGA 19409

Query: 969   AITGYTIQKADKKSMEWFTV-IEHYHRTSATITELVIGNEYYFRVFSENMC-GLSEDATM 1026
              ITGY +++ +     W      +   T   +TEL     Y FRVF+ N    +SE +  
Sbjct: 19410 KITGYIVERRELPDGRWLKCNYTNIQETYFEVTELTEDQRYEFRVFARNAADSVSEPSES 19469

Query: 1027  TKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKIT 1086
             T    +I +D  +    V  D  F +  +           AG    +N  + G P P I+
Sbjct: 19470 T--GPIIVKDD-VEPPRVMMDVKFRDVIVVK---------AGEVLKINADIAGRPLPVIS 19517

Query: 1087  WMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGT--VEIECKL 1141
             W K+ + I +  R  + S      L ++     D G Y     N  GT  V + CK+
Sbjct: 19518 WAKDGIEIEERARTEIISTDNHTLLTVKDCIRRDTGQYVLTLKNVAGTRSVAVNCKV 19574



 Score = 92.0 bits (227), Expect = 3e-18
 Identities = 69/216 (31%), Positives = 100/216 (46%), Gaps = 18/216 (8%)

Query: 937   DRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTV-IEHYHRT 995
             ++PG P    I  V  ++  + W PP  DG A I  Y ++K +KK  +W +V  E    T
Sbjct: 24518 EKPGAPGKPTITAVTKDSCVVAWKPPASDGGAKIRNYYLEKREKKQNKWISVTTEEIRET 24577

Query: 996   SATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFS-EAP 1054
               ++  L+ G EY FRV  EN+ G SE + +++              P+    D   +AP
Sbjct: 24578 VFSVKNLIEGLEYEFRVKCENLGGESEWSEISE--------------PITPKSDVPIQAP 24623

Query: 1055  MFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMK-NKVAIVDDPRYRMFS-NQGVCTLE 1112
              F + L N       NATL C V G+PKP + W +  K  I D  +YR+     G   L 
Sbjct: 24624 HFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQLI 24683

Query: 1113  IRKPSPYDGGTYCCKAVNDLGTVEIECKLEVKVIAQ 1148
             I   +  D   Y  +A N  G+V     LEV+V A+
Sbjct: 24684 IASVTDDDATVYQVRATNQGGSVSGTASLEVEVPAK 24719



 Score = 90.9 bits (224), Expect = 6e-18
 Identities = 99/442 (22%), Positives = 167/442 (37%), Gaps = 60/442 (13%)

Query: 722   VNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEY 781
             +  + +  P  P  PF             +  +     ++ W  P   G + +  Y++E 
Sbjct: 12679 IKVVVMDAPGPPQPPF------------DISDIDADACSLSWHIPLEDGGSNITNYIVEK 12726

Query: 782   CFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEI- 840
             C     DW+ A    + KT   +  L    +   RV+A N  G SEP   + P +V +  
Sbjct: 12727 CDVSRGDWVTALAS-VTKTSCRVGKLIPGQEYIFRVRAENRFGISEP--LTSPKMVAQFP 12783

Query: 841   ----IEPPKIRIPRHLKQ----TYIRRVGEAVNLVIPF--QGKPRPELTWKKDGAEIDKN 890
                  EP   R+ +  K      + R   +  + +I +  + K R  L W K       N
Sbjct: 12784 FGVPSEPKNARVTKVNKDCIFVAWDRPDSDGGSPIIGYLIERKERNSLLWVK------AN 12837

Query: 891   QINIRNSETDTIIFIRKAERS------HSGKYDLQVKVDKFVETASIDIQIIDRPGPPQI 944
                +R++E      +   E S      +        K  ++V TA + +   D PG P++
Sbjct: 12838 DTLVRSTEYPCAGLVEGLEYSFRIYALNKAGSSPPSKPTEYV-TARMPV---DPPGKPEV 12893

Query: 945   VKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWF---TVIEHYHRTSATITE 1001
             +   DV    V+L W  PK DG + I GY ++       +W    T      +   T T 
Sbjct: 12894 I---DVTKSTVSLIWARPKHDGGSKIIGYFVEACKLPGDKWVRCNTAPHQIPQEEYTATG 12950

Query: 1002  LVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLV 1061
             L    +Y FR  +     +S  +  +    ++A +      P   D   +   + T    
Sbjct: 12951 LEEKAQYQFRAIARTAVNISPPSEPSDPVTILAENV-----PPRIDLSVAMKSLLTVK-- 13003

Query: 1062  NTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDG 1121
                  AG N  L+ +V G P P ++W K+   +      +M   + +CTLE+   +  D 
Sbjct: 13004 -----AGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDS 13058

Query: 1122  GTYCCKAVNDLGTVEIECKLEV 1143
             G Y   A N  G+     KL+V
Sbjct: 13059 GDYTITAENSSGSKSATIKLKV 13080



 Score = 89.4 bits (220), Expect = 2e-17
 Identities = 117/543 (21%), Positives = 204/543 (37%), Gaps = 60/543 (11%)

Query: 628   NEAGEAHASIKVKVVDFPDP-----PVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIE 682
             N AG   AS+        DP     P  P VT+       + W PP  DGGS + GY +E
Sbjct: 10094 NAAGVGPASLPSDPATARDPIAPPGPPFPKVTDWTKSSADLEWSPPLKDGGSKVTGYIVE 10153

Query: 683   RKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAV 742
              K++    W +      + T      + EG  Y+   F V A+ I+    P    V   +
Sbjct: 10154 YKEEGKEEWEKGKDKEVRGTKLVVTGLKEGAFYK---FRVRAVNIAGIGEPGE--VTDVI 10208

Query: 743   TSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKF 802
                  L++ D   D +V  R R   H G        +      T  W +  + L  +   
Sbjct: 10209 EMKDRLVSPDLQLDASV--RDRIVVHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEATI 10266

Query: 803   TITGLPTDAKI---------FVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIP---- 849
               T + +   I            + A N AG  +     + I+V  +  P  +  P    
Sbjct: 10267 ETTAISSSMVIKNCQRSHQGVYSLLAKNEAGERK-----KTIIVDVLDVPGPVGTPFLAH 10321

Query: 850   ----RHLKQTYIRRVGEAVNLVIPF--QGKPRPELTWKKDGAEIDKNQINIRNSETDTII 903
                    K T+     +  + +  +  + +      W      + +    ++        
Sbjct: 10322 NLTNESCKLTWFSPEDDGGSPITNYVIEKRESDRRAWTPVTYTVTRQNATVQGLIQGKAY 10381

Query: 904   FIRKAERSHSGKYDLQVKVDKFVETASIDI--QIIDRPGPPQIVKIEDVWGENVALTWTP 961
             F R A  +  G       +  FVET+   +  + I  P  P+ +++++V    V LTW P
Sbjct: 10382 FFRIAAENSIG-------MGPFVETSEALVIREPITVPERPEDLEVKEVTKNTVTLTWNP 10434

Query: 962   PKDDGNAAITGYTIQKADKKSMEWFTVI-EHYHRTSATITELVIGNEYYFRVFSENMCGL 1020
             PK DG + I  Y ++     + ++  V  ++      T+  L  G+ Y +RV + N+ G 
Sbjct: 10435 PKYDGGSEIINYVLESRLIGTEKFHKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQ 10494

Query: 1021  SEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGN 1080
              + +  TK    I    ++    ++ DF        T  +   +A+ G  +       G 
Sbjct: 10495 GKPSFCTKP---ITCKDELAPPTLHLDF----RDKLTIRVGEAFALTGRYS-------GK 10540

Query: 1081  PKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECK 1140
             PKPK++W K++  +++D R  + +      LE  K    D G YC    N  G+ +  C+
Sbjct: 10541 PKPKVSWFKDEADVLEDDRTHIKTTPATLALEKIKAKRSDSGKYCVVVENSTGSRKGFCQ 10600

Query: 1141  LEV 1143
             + V
Sbjct: 10601 VNV 10603



 Score = 87.0 bits (214), Expect = 9e-17
 Identities = 96/437 (21%), Positives = 162/437 (37%), Gaps = 75/437 (17%)

Query: 625   NLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERK 684
             N+  ++  +  S  +  +D  DPP  P    +      + W  P Y GG  I  Y +E++
Sbjct: 15032 NMAGKSKPSKPSEPMLALDPIDPPGKPVPLNITRHTVTLKWAKPEYTGGFKITSYIVEKR 15091

Query: 685   KKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIG-ISKPSMPSRPFVPLAVT 743
                + RW++ NF    E  F    + E  AYE R+ A NA G IS PS PS         
Sbjct: 15092 DLPNGRWLKANFSNILENEFTVSGLTEDAAYEFRVIAKNAAGAISPPSEPSDAITCRDDV 15151

Query: 744   SPPTLLTVDSVTDTTV-------------------TMRWRP--PDHIGAAGLDGYVLEYC 782
               P +       DT +                   TM W     +  G A L+  + ++ 
Sbjct: 15152 EAPKIKVDVKFKDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFS 15211

Query: 783   FEGTEDWIVANKDLI--DKTKFTITGLPTD--AKIFVRVKAVNAAGASEPKYYSQPILVK 838
                     + NKD    D   +T+T       AK    VK ++  G  E      P+ V 
Sbjct: 15212 TN------LVNKDSTRRDSGAYTLTATNPGGFAKHIFNVKVLDRPGPPE-----GPLAVT 15260

Query: 839   EIIE--------PPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKN 890
             E+          PP            +   G  ++  I  Q +    L W    +E+   
Sbjct: 15261 EVTSEKCVLSWFPP------------LDDGGAKIDHYI-VQKRETSRLAWTNVASEVQVT 15307

Query: 891   QINI-RNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIED 949
             ++ + +  + +  IF   A   +     L+           + +     P PP+  ++  
Sbjct: 15308 KLKVTKLLKGNEYIFRVMAVNKYGVGEPLE-------SEPVLAVNPYGPPDPPKNPEVTT 15360

Query: 950   VWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWF-----TVIEHYHRTSATITELVI 1004
             +  +++ + W  P  DG + I  Y +++ DK    W      T+ +  ++ S     L  
Sbjct: 15361 ITKDSMVVCWGHPDSDGGSEIINYIVERRDKAGQRWIKCNKKTLTDLRYKVSG----LTE 15416

Query: 1005  GNEYYFRVFSENMCGLS 1021
             G+EY FR+ +EN  G+S
Sbjct: 15417 GHEYEFRIMAENAAGIS 15433



 Score = 86.3 bits (212), Expect = 2e-16
 Identities = 94/359 (26%), Positives = 158/359 (44%), Gaps = 23/359 (6%)

Query: 310  WYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVT---AGDEKCST-ELFVREP 365
            W K+G  IR S K+ F   G  R L I + Q++D  EY         EK ST +L V E 
Sbjct: 4846 WMKDGSNIRESPKHRFIADGKDRKLHIIDVQLSDAGEYTCVLRLGNKEKTSTAKLVVEEL 4905

Query: 366  PIMVTKQL-EDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHI 424
            P+   K L E+ T   G+ + L CE+++ + +V W K+G+ ++  P  R    V G    
Sbjct: 4906 PVRFVKTLEEEVTVVKGQPLYLSCELNK-ERDVVWRKDGKIVVEKP-GRIVPGVIGLMRA 4963

Query: 425  LIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKIL-----TPLTDQTVNLGKEICLKC 479
            L I  A   DA  Y+V T    ++ + S  +K ++++      P+ DQ V         C
Sbjct: 4964 LTINDADDTDAGTYTV-TVENANNLECSSCVKVVEVIRDWLVKPIRDQHVKPKGTAIFAC 5022

Query: 480  EISENIPG-KWTK--NGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVT 536
            +I+++ P  KW K  + +P + +D+ +++  G    L I NA+ ED  +Y  A +     
Sbjct: 5023 DIAKDTPNIKWFKGYDEIPAEPNDKTEILRDGNHLYLKIKNAMPEDIAEY--AVEIEGKR 5080

Query: 537  LPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSG 596
             PAK+ + +    +L  ++    VT+        +  IS    P     +G+  ++  S 
Sbjct: 5081 YPAKLTLGEREVELLKPIE---DVTIYEKESASFDAEISEADIPGQWKLKGE--LLRPSP 5135

Query: 597  RIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTE 655
                ++      L +   + D +G       N    A  ++K   +DF  P    TV E
Sbjct: 5136 TCEIKAEGGKRFLTLHKVKLDQAGEVLYQALNAITTAILTVKEIELDFAVPLKDVTVPE 5194



 Score = 86.3 bits (212), Expect = 2e-16
 Identities = 104/434 (23%), Positives = 164/434 (37%), Gaps = 44/434 (10%)

Query: 722   VNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEY 781
             ++ I + KP  P  P            +  D V+   V + W PP + G   +  Y++E 
Sbjct: 18092 LSVIVLEKPGPPVGP------------VRFDEVSADFVVISWEPPAYTGGCQISNYIVEK 18139

Query: 782   CFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILV---- 837
                 T  W + +   + +T   IT L T  +   R+ A N  G S P   S+ ++V    
Sbjct: 18140 RDTTTTTWHMVSAT-VARTTIKITKLKTGTEYQFRIFAENRYGKSAP-LDSKAVIVQYPF 18197

Query: 838   KEIIEPPKIRIPRHLKQTYIRRVGEAVN------LVIPFQGKPRPELTWKKDGAEIDKNQ 891
             KE   P    +    K   + +  E VN      +    + K +  + W K    ++K  
Sbjct: 18198 KEPGPPGTPFVTSISKDQMLVQWHEPVNDGGTKIIGYHLEQKEKNSILWVK----LNKTP 18253

Query: 892   INIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVW 951
             I     +T  +    + E   S +  + +     V    +     D PG P+ + I    
Sbjct: 18254 IQDTKFKTTGLDEGLEYEFKVSAENIVGIGKPSKVSECFVARDPCDPPGRPEAIVITR-- 18311

Query: 952   GENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTV-IEHYHRTSATITELVIGNEYYF 1010
               NV L W  P  DG + ITGY ++K D     W      +   T  T++ LV    Y F
Sbjct: 18312 -NNVTLKWKKPAYDGGSKITGYIVEKKDLPDGRWMKASFTNVLETEFTVSGLVEDQRYEF 18370

Query: 1011  RVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYN 1070
             RV + N  G   + +     A+ ARD     N   +       P +   +V     AG  
Sbjct: 18371 RVIARNAAGNFSEPS-DSSGAITARDEIDAPNASLD-------PKYKDVIV---VHAGET 18419

Query: 1071  ATLNCSVRGNPKPKITWMKNKVAIVDD-PRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAV 1129
               L   +RG P P + W K+   + +   R  + S     TL ++     DGG Y  K  
Sbjct: 18420 FVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQYILKLS 18479

Query: 1130  NDLGTVEIECKLEV 1143
             N  GT  I   ++V
Sbjct: 18480 NVGGTKSIPITVKV 18493



 Score = 86.3 bits (212), Expect = 2e-16
 Identities = 78/292 (26%), Positives = 125/292 (42%), Gaps = 60/292 (20%)

Query: 290   DKGGRVRFV--VELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEY 347
             ++GG V++V  +E  D   +V WY   +++  S KY   ++    IL++ +    DD  Y
Sbjct: 25275 EEGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTY 25334

Query: 348   YVTA----GDEKCSTELFVR---------------------------EPPIMVTKQLEDT 376
                     G++    ELFV+                           E P   T  L + 
Sbjct: 25335 RCKVVNDYGEDSSYAELFVKGVREVYDYYCRRTMKKIKRRTDTMRLLERPPEFTLPLYNK 25394

Query: 377   TAYCGERVELECEVS-EDDANVKWFKNGEEIIPGPK-SRYRIRVEGKKHILIIEGATKAD 434
             TAY GE V     ++   + +V W+K+G++I PG    +Y    +   + L I   T  D
Sbjct: 25395 TAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDD 25454

Query: 435   AAEYSVMTTG--GQSS--AKLSVDLKPLKILTPLTDQTV-------------NLGKEICL 477
              AEY+V+     G+ S  AKL+V L P     P TD T+               G+ +C 
Sbjct: 25455 DAEYTVVARNKYGEDSCKAKLTVTLHP-----PPTDSTLRPMFKRLLANAECQEGQSVCF 25509

Query: 478   KCEISENIPG--KWTKNGLPVQESDRLKVVHKG-RIHKLVIANALTEDEGDY 526
             +  +S   P   KW K+G P+     ++++H+G   + L I + L ED G Y
Sbjct: 25510 EIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYY 25561



 Score = 85.9 bits (211), Expect = 2e-16
 Identities = 102/444 (22%), Positives = 169/444 (38%), Gaps = 63/444 (14%)

Query: 721   AVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLE 780
             ++  + + KP  P  P            +  D V+  ++T+ W PP + G   +  Y+++
Sbjct: 17009 SIEIVTLDKPDPPKGP------------VKFDDVSAESITLSWNPPLYTGGCQITNYIVQ 17056

Query: 781   YCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEI 840
                  T  W V +   + +T   +T L T  +   R+ A N  G S     S PI+ +  
Sbjct: 17057 KRDTTTTVWDVVSAT-VARTTLKVTKLKTGTEYQFRIFAENRYGQSFA-LESDPIVAQYP 17114

Query: 841   IE---PPKIRIPRHL-KQTYIRRVGEAVN------LVIPFQGKPRPELTWKKDGAEIDKN 890
              +   PP       + K + + +  E VN      +    + K R  + W K    ++K 
Sbjct: 17115 YKEPGPPGTPFATAISKDSMVIQWHEPVNNGGSPVIGYHLERKERNSILWTK----VNKT 17170

Query: 891   QINIRNSETDTIIFIRKAERSHSG-KYDLQVKVDKFVETAS--------IDIQIIDRPGP 941
              I+      DT     KA+    G +Y+ +V  +  V            +     D PG 
Sbjct: 17171 IIH------DTQF---KAQNLEEGIEYEFRVYAENIVGVGKASKNSECYVARDPCDPPGT 17221

Query: 942   PQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTV-IEHYHRTSATIT 1000
             P+ + ++      + L WT P  DG + ITGY ++K D     W      +   T  T++
Sbjct: 17222 PEPIMVKR---NEITLQWTKPVYDGGSMITGYIVEKRDLPDGRWMKASFTNVIETQFTVS 17278

Query: 1001  ELVIGNEYYFRVFSENMCG-LSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQP 1059
              L     Y FRV ++N  G +S+ +  T         G I      E    S  P F   
Sbjct: 17279 GLTEDQRYEFRVIAKNAAGAISKPSDST---------GPITAKDEVELPRISMDPKFRDT 17329

Query: 1060  LVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPY 1119
             +V     AG    L   V G P P I W++    I +  R  + +      L ++     
Sbjct: 17330 IVVN---AGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRI 17386

Query: 1120  DGGTYCCKAVNDLGTVEIECKLEV 1143
             DGG Y  +A N  G+      ++V
Sbjct: 17387 DGGQYILRASNVAGSKSFPVNVKV 17410



 Score = 84.3 bits (207), Expect = 6e-16
 Identities = 105/451 (23%), Positives = 168/451 (37%), Gaps = 79/451 (17%)

Query: 722   VNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEY 781
             +  I + KP  P+ P            + +D +  T++T+ W PP+  G A L GYV+E 
Sbjct: 23519 IKVIILDKPGPPTGP------------IKIDEIDATSITISWEPPELDGGAPLSGYVVEQ 23566

Query: 782   CFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEII 841
                    W+  ++  + ++ F  T L    +   RV A N  G           L  E+I
Sbjct: 23567 RDAHRPGWLPVSES-VTRSTFKFTRLTEGNEYVFRVAATNRFGIGS-------YLQSEVI 23618

Query: 842   E-PPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTW---KKDGAE------IDKNQ 891
             E    IRIP           G    L I    +    LTW   + DG        +++ +
Sbjct: 23619 ECRSSIRIP-----------GPPETLQIFDVSRDGMTLTWYPPEDDGGSQVTGYIVERKE 23667

Query: 892   INIR-----NSETDTIIFIRKAERSHSGKYDLQVKVDKFVETAS--------IDIQIIDR 938
             +        N    T+   R    +   +Y+ +V       +          + +  I  
Sbjct: 23668 VRADRWVRVNKVPVTMTRYRSTGLTEGLEYEHRVTAINARGSGKPSRPSKPIVAMDPIAP 23727

Query: 939   PGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWF------TVIEHY 992
             PG PQ  ++ D    +V+L W+ P+D+G + +TGY I+       EW       T I  Y
Sbjct: 23728 PGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTKCNTTPTKIREY 23787

Query: 993   HRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSE 1052
                  T+T L  G EY FRV + N  G  E A        +    K+ +   Y D++  E
Sbjct: 23788 -----TLTHLPQGAEYRFRVLACNAGGPGEPAE-------VPGTVKVTEMLEYPDYELDE 23835

Query: 1053  APMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLE 1112
                  +     +   G    L   ++G P P   W K    I    R  + +++    L 
Sbjct: 23836 -----RYQEGIFVRQGGVIRLTIPIKGKPFPICKWTKEGQDI--SKRAMIATSETHTELV 23888

Query: 1113  IRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1143
             I++    D GTY     N  G   +  K+ V
Sbjct: 23889 IKEADRGDSGTYDLVLENKCGKKAVYIKVRV 23919



 Score = 82.8 bits (203), Expect = 2e-15
 Identities = 59/194 (30%), Positives = 92/194 (47%), Gaps = 21/194 (10%)

Query: 572  IPISGEPPPKAMWSRGDKAIMEGSGRIRTE-------SYPDSSTLVIDIAERDDSGVYHI 624
            + +  EPP         + ++E   R+ T        + PD +  V D+ E  +   + +
Sbjct: 7895 VDLKWEPPKNDGGRPIQRYVIEKKERLGTRWVKAGKTAGPDCNFRVTDVIEGTEVQ-FQV 7953

Query: 625  NLKNEAGEAHASIKVKVVDFPDPPVAPT------VTEVGDDWCIMNWEPPAYDGGSPILG 678
              +NEAG  H S   +++   DP   P+      VT+ G     + W+PP  +GGSPI+G
Sbjct: 7954 RAENEAGVGHPSEPTEILSIEDPTSPPSPPLDLHVTDAGRKHIAIAWKPPEKNGGSPIIG 8013

Query: 679  YFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVA----YEVRIFAVNAIGISKPSMPS 734
            Y +E     + +WMR+N    K+  F   K+ EGV     Y +R+ AVNAIG+S+PS  S
Sbjct: 8014 YHVEMCPVGTEKWMRVNSRPIKDLKF---KVEEGVVPDKEYVLRVRAVNAIGVSEPSEIS 8070

Query: 735  RPFVPLAVTSPPTL 748
               V       PT+
Sbjct: 8071 ENVVAKDPDCKPTI 8084



 Score = 80.9 bits (198), Expect = 7e-15
 Identities = 77/261 (29%), Positives = 107/261 (40%), Gaps = 22/261 (8%)

Query: 489  WTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPD--AYNVTLPAKVHVIDP 546
            W K+G  V+ SDRL + +      L +  ++  D G Y    +    + T    V VI  
Sbjct: 8115 WHKDGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATASINVKVIGL 8174

Query: 547  PKIILDGLDADNTVTVIAGNKLRLEIP--ISGEPPPKAMWSRGDKA------IMEGSGRI 598
            P    D   +D T    +  KL  E P    G P    +  R +        +M G  ++
Sbjct: 8175 PGPCKDIKASDITK---SSCKLTWEPPEFDGGTPILHYVLERREAGRRTYIPVMSGENKL 8231

Query: 599  R---TESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTE 655
                 +  P+        A     G  +I LKN        I       PDPPV   V  
Sbjct: 8232 SWTVKDLIPNGEYFFRVKAVNKVGGGEYIELKNPV------IAQDPKQPPDPPVDVEVHN 8285

Query: 656  VGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAY 715
               +   + W+PP YDGGS I+GY IE+  K   RW R N  L    T+  K + EG  Y
Sbjct: 8286 PTAEAMTITWKPPLYDGGSKIMGYIIEKIAKGEERWKRCNEHLVPILTYTAKGLEEGKEY 8345

Query: 716  EVRIFAVNAIGISKPSMPSRP 736
            + R+ A NA GIS+PS  + P
Sbjct: 8346 QFRVRAENAAGISEPSRATPP 8366



 Score = 75.5 bits (184), Expect = 3e-13
 Identities = 105/447 (23%), Positives = 173/447 (38%), Gaps = 58/447 (12%)

Query: 721   AVNAIGISKPSMPSR-PFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVL 779
             A NA G +K  +  +    P  V  P   +   ++T   +T+ W  P + G A +  Y++
Sbjct: 21728 AKNASGSAKAEIKVKVQDTPGKVVGP---IRFTNITGEKMTLWWDAPLNDGCAPITHYII 21784

Query: 780   EYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVK- 838
             E        W +  +D  +   +T   L    +   RV AVN  G   P   S P++ + 
Sbjct: 21785 EKRETSRLAWALI-EDKCEAQSYTAIKLINGNEYQFRVSAVNKFGVGRP-LDSDPVVAQI 21842

Query: 839   --EIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRN 896
                + + P I  P ++        G ++ L        RPE      G+EI +  +  R 
Sbjct: 21843 QYTVPDAPGIPEPSNI-------TGNSITLTWA-----RPE---SDGGSEIQQYILERRE 21887

Query: 897   SE-TDTIIFIRKAERSHS----------GKYDLQVKVDKF--VETASIDIQII------D 937
              + T  +  I K   S +           +Y+  V  +    V  AS   ++I      +
Sbjct: 21888 KKSTRWVKVISKRPISETRFKVTGLTEGNEYEFHVMAENAAGVGPASGISRLIKCREPVN 21947

Query: 938   RPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTV-IEHYHRTS 996
              PGPP +VK+ D     V+L W+ P  DG   I GY I+       +W  V  E   +T 
Sbjct: 21948 PPGPPTVVKVTDTSKTTVSLEWSKPVFDGGMEIIGYIIEMCKADLGDWHKVNAEACVKTR 22007

Query: 997   ATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMF 1056
              T+T+L  G EY FRV + N  G  +   +T     I    ++    +  D +F +  + 
Sbjct: 22008 YTVTDLQAGEEYKFRVSAINGAGKGDSCEVT---GTIKAVDRLTAPELDIDANFKQTHVV 22064

Query: 1057  TQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKP 1116
                       AG +  L  + +G P P   W K    +    R  + +     TL +   
Sbjct: 22065 R---------AGASIRLFIAYQGRPTPTAVWSKPDSNL--SLRADIHTTDSFSTLTVENC 22113

Query: 1117  SPYDGGTYCCKAVNDLGTVEIECKLEV 1143
             +  D G Y     N+ G+  I   ++V
Sbjct: 22114 NRNDAGKYTLTVENNSGSKSITFTVKV 22140



 Score = 73.9 bits (180), Expect = 8e-13
 Identities = 64/235 (27%), Positives = 91/235 (38%), Gaps = 46/235 (19%)

Query: 939  PGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRT-SA 997
            P PP  V++ +   E + +TW PP  DG + I GY I+K  K    W    EH     + 
Sbjct: 8275 PDPPVDVEVHNPTAEAMTITWKPPLYDGGSKIMGYIIEKIAKGEERWKRCNEHLVPILTY 8334

Query: 998  TITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFT 1057
            T   L  G EY FRV +EN  G+SE +  T  +  +            +  D  +  + T
Sbjct: 8335 TAKGLEEGKEYQFRVRAENAAGISEPSRATPPTKAV------------DPIDAPKVILRT 8382

Query: 1058 QPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDD-------PRYRM-------- 1102
               V      G    L+ S+ G+P P ITW+K++  IV +       P  R         
Sbjct: 8383 SLEVKR----GDEIALDASISGSPYPTITWIKDENVIVPEEIKKRAAPLVRRRKGEVQEE 8438

Query: 1103 --------------FSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1143
                           S +G   L +R     D G Y  K  ND G  +  C + V
Sbjct: 8439 EPFVLPLTQRLSIDNSKKGESQLRVRDSLRPDHGLYMIKVENDHGIAKAPCTVSV 8493



 Score = 73.9 bits (180), Expect = 8e-13
 Identities = 59/203 (29%), Positives = 83/203 (40%), Gaps = 14/203 (6%)

Query: 933   IQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHY 992
             ++  + P PP  + I D+    V+L W  PK DG + ITGY I+   K S +W T I   
Sbjct: 14654 VKASEAPSPPDSLNIMDITKSTVSLAWPKPKHDGGSKITGYVIEAQRKGSDQW-THITTV 14712

Query: 993   HRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSE 1052
                   +  L  G EY F+V + N  G S      +ES  +     + +  +  + D   
Sbjct: 14713 KGLECVVRNLTEGEEYTFQVMAVNSAGRSAP----RESRPVI----VKEQTMLPELDLRG 14764

Query: 1053  APMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLE 1112
                  Q LV   A AG N  +   V G PKP +TW K    +    R    +      L 
Sbjct: 14765 ---IYQKLV--IAKAGDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILN 14819

Query: 1113  IRKPSPYDGGTYCCKAVNDLGTV 1135
             I +    D G Y   A N +G V
Sbjct: 14820 INECVRSDSGPYPLTARNIVGEV 14842



 Score = 73.2 bits (178), Expect = 1e-12
 Identities = 52/197 (26%), Positives = 86/197 (43%), Gaps = 13/197 (6%)

Query: 937   DRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTS 996
             ++P PP+ + + D    +  L W  P  DG + ITGY ++   K S  W     H  + +
Sbjct: 22239 EQPAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSDFWVEA-GHTKQLT 22297

Query: 997   ATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMF 1056
              T+  LV   EY FRV ++N  G SE       S+VI ++ +I           ++    
Sbjct: 22298 FTVERLVEKTEYEFRVKAKNDAGYSEPREAF--SSVIIKEPQIEPT--------ADLTGI 22347

Query: 1057  TQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKP 1116
             T  L+   A  G   T++  + G P PK+TW   ++ + +  R  + + +   TL ++  
Sbjct: 22348 TNQLITCKA--GSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVSITTTKDRTTLTVKDS 22405

Query: 1117  SPYDGGTYCCKAVNDLG 1133
                D G Y     N  G
Sbjct: 22406 MRGDSGRYFLTLENTAG 22422



 Score = 68.9 bits (167), Expect = 3e-11
 Identities = 135/688 (19%), Positives = 232/688 (33%), Gaps = 145/688 (21%)

Query: 2     PEPTKKEENEVPAP----APPPEEPSKEKEAGTTPAKDEEEVSPPSALPPGLGSRALERK 57
             PEP  K    V +P    +P P  P       T P   E+    P + PP +        
Sbjct: 26364 PEPRVKSPEAVKSPKRVKSPEPSHPKAVSPTETKPTPTEKVQHLPVSAPPKITQ------ 26417

Query: 58    DSDWTLVETPPGEEQAKQNANSQLSILFIEKPQGGTVKVGEDITFIAKVKAEDLLRKPTI 117
                                        F++       +  ++I  +  V    +LR   +
Sbjct: 26418 ---------------------------FLK------AEASKEIAKLTCVVESSVLRAKEV 26444

Query: 118   KWFKGKWMDLASKAGKHLQLKETFERH-SRVYTFEMQIIKAKDNFAGNYRCEVTYKDKFD 176
              W+K          GK L+    F+ H S   T+E++I    ++  G Y CE+       
Sbjct: 26445 TWYKD---------GKKLKENGHFQFHYSADGTYELKINNLTESDQGEYVCEI------- 26488

Query: 177   SCSFDLEVHESTGTTPNIDIRSAFKRSGEGQEDAGELDFSG---------LLKRREVKQQ 227
                                       SGEG      L F G         + K  E K+ 
Sbjct: 26489 --------------------------SGEGGTSKTNLQFMGQAFKSIHEKVSKISETKKS 26522

Query: 228   EEEPQVDVWELLKNAKPSEYEKIAFQYGITDLRGMLKRLKRMRREEKKSAAFAKILDPAY 287
             +++       + +  +P   E I+                       K      + D   
Sbjct: 26523 DQKTTEST--VTRKTEPKAPEPIS----------------------SKPVIVTGLQDTTV 26558

Query: 288   QVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEY 347
               D   +   V    +P+    W K+G+ I    KY          L I+    +D   Y
Sbjct: 26559 SSDSVAKFA-VKATGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLY 26617

Query: 348   YVT----AGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNG 403
               T    AG    S +L ++   I  T+  + +T    E    +  V +++ + K  ++ 
Sbjct: 26618 TCTVKNSAGSVSSSCKLTIKA--IKDTEAQKVSTQKTSEITPQKKAVVQEEISQKALRSE 26675

Query: 404   EEIIPGPKSRYRIRVEGKKHILIIEGATKADAA---EYSVMTTGGQSSAKLSVDLKP-LK 459
             E  +   KS+ ++ ++ +   ++I    K  AA   E S++      +++ S +++   +
Sbjct: 26676 EIKMSEAKSQEKLALKEEASKVLISEEVKKSAATSLEKSIVHEEITKTSQASEEVRTHAE 26735

Query: 460   ILTPLTDQTVNLGKEICLKCEISENIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANAL 519
             I    T  ++N G+ + LK  I+     KW  NG+ +  S+  +    G    L I  A 
Sbjct: 26736 IKAFSTQMSINEGQRLVLKANIAGATDVKWVLNGVELTNSEEYRYGVSGSDQTLTIKQAS 26795

Query: 520   TEDEGDYV--------FAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLE 571
               DEG                Y++TL  ++   D P  I        +  +  G  +   
Sbjct: 26796 HRDEGILTCISKTKEGIVKCQYDLTLSKELS--DAPAFI----SQPRSQNINEGQNVLFT 26849

Query: 572   IPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAG 631
               ISGEP P+  W + +  I   S  +      +  +L I  A   DSG Y I  KN  G
Sbjct: 26850 CEISGEPSPEIEWFKNNLPI-SISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRG 26908

Query: 632   EAHASIKVKVVDFPDPPVAPTVTEVGDD 659
             +  A+  + V+   + P    V     D
Sbjct: 26909 QCSATASLMVLPLVEEPSREVVLRTSGD 26936



 Score = 66.2 bits (160), Expect = 2e-10
 Identities = 94/408 (23%), Positives = 146/408 (35%), Gaps = 40/408 (9%)

Query: 742   VTSPPT-LLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKT 800
             +  PPT  +  D V+   VT  W PP++ G   +  YV+E     +  W+     +I +T
Sbjct: 14853 IPGPPTGPIKFDEVSSDFVTFSWDPPENDGGVPISNYVVEMRQTDSTTWVELATTVI-RT 14911

Query: 801   KFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQ-TYIRR 859
              +  T L T  +   RVKA N  G   P   S  I+      P K+  P    Q T + +
Sbjct: 14912 TYKATRLTTGLEYQFRVKAQNRYGVG-PGITSACIVANY---PFKVPGPPGTPQVTAVTK 14967

Query: 860   VGEAVNLVIPF------------QGKPRPELTWKKDGAEIDKNQINIRNSETDTIIF-IR 906
                 ++   P             + K R  + W+     +    I   +  TD I +  R
Sbjct: 14968 DSMTISWHEPLSDGGSPILGYHVERKERNGILWQTVSKALVPGNIFKSSGLTDGIAYEFR 15027

Query: 907   KAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDG 966
                 + +GK     K  K  E   + +  ID PG P  + I       V L W  P+  G
Sbjct: 15028 VIAENMAGKS----KPSKPSEPM-LALDPIDPPGKPVPLNITR---HTVTLKWAKPEYTG 15079

Query: 967   NAAITGYTIQKADKKSMEWFTV-IEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDAT 1025
                IT Y ++K D  +  W      +      T++ L     Y FRV ++N  G     +
Sbjct: 15080 GFKITSYIVEKRDLPNGRWLKANFSNILENEFTVSGLTEDAAYEFRVIAKNAAGAISPPS 15139

Query: 1026  MTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKI 1085
                ++     D +  K  V  D  F +  +           AG    L   V G P P +
Sbjct: 15140 EPSDAITCRDDVEAPKIKV--DVKFKDTVILK---------AGEAFRLEADVSGRPPPTM 15188

Query: 1086  TWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLG 1133
              W K+   +    +  +        L  +  +  D G Y   A N  G
Sbjct: 15189 EWSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDSGAYTLTATNPGG 15236



 Score = 64.7 bits (156), Expect = 5e-10
 Identities = 75/303 (24%), Positives = 129/303 (42%), Gaps = 19/303 (6%)

Query: 366  PIMVTKQLEDT----TAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGK 421
            P+   K+++D     + + G     EC VS   A   W K+G  I   PK  +R   +GK
Sbjct: 4809 PLKFVKEIKDIILTESEFVGSSAIFECLVSPSTAITTWMKDGSNIRESPK--HRFIADGK 4866

Query: 422  KHILIIEGATKADAAEYSVMTTGGQ----SSAKLSVDLKPLKILTPLTDQ-TVNLGKEIC 476
               L I     +DA EY+ +   G     S+AKL V+  P++ +  L ++ TV  G+ + 
Sbjct: 4867 DRKLHIIDVQLSDAGEYTCVLRLGNKEKTSTAKLVVEELPVRFVKTLEEEVTVVKGQPLY 4926

Query: 477  LKCEISENIPGKWTKNG-LPVQESDRLKVVHKGRIHKLVIANALTEDEGDY-VFAPDAYN 534
            L CE+++     W K+G + V++  R+     G +  L I +A   D G Y V   +A N
Sbjct: 4927 LSCELNKERDVVWRKDGKIVVEKPGRIVPGVIGLMRALTINDADDTDAGTYTVTVENANN 4986

Query: 535  VTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEG 594
            +   + V V++   +I D L        +      +      +  P   W +G   I   
Sbjct: 4987 LECSSCVKVVE---VIRDWLVKPIRDQHVKPKGTAIFACDIAKDTPNIKWFKGYDEI-PA 5042

Query: 595  SGRIRTESYPDSSTLVIDI--AERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPT 652
                +TE   D + L + I  A  +D   Y + ++ +   A  ++  + V+   P    T
Sbjct: 5043 EPNDKTEILRDGNHLYLKIKNAMPEDIAEYAVEIEGKRYPAKLTLGEREVELLKPIEDVT 5102

Query: 653  VTE 655
            + E
Sbjct: 5103 IYE 5105



 Score = 63.5 bits (153), Expect = 1e-09
 Identities = 31/92 (33%), Positives = 43/92 (46%)

Query: 1054 PMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEI 1113
            P     L N   I G + TL C + G P P +TW +    I     +++    G+  L I
Sbjct: 897  PTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLMI 956

Query: 1114 RKPSPYDGGTYCCKAVNDLGTVEIECKLEVKV 1145
            R+    D G + C AVN+ GTV   C L V+V
Sbjct: 957  REAFAEDSGRFTCSAVNEAGTVSTSCYLAVQV 988



 Score = 61.2 bits (147), Expect = 5e-09
 Identities = 33/100 (33%), Positives = 54/100 (54%), Gaps = 6/100 (6%)

Query: 938   RPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEH-YHRTS 996
             RP PP++ K+     E + + W PP+ DG  +ITGY ++K +K S  W  V +       
Sbjct: 12093 RPDPPEVTKVSK---EEMTVVWNPPEYDGGKSITGYFLEKKEKHSTRWVPVNKSAIPERR 12149

Query: 997   ATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARD 1036
               +  L+  +EY FRV +EN  G+ E +  ++   V+A+D
Sbjct: 12150 MKVQNLLPDHEYQFRVKAENEIGIGEPSLPSR--PVVAKD 12187



 Score = 59.7 bits (143), Expect = 2e-08
 Identities = 74/324 (22%), Positives = 129/324 (39%), Gaps = 19/324 (5%)

Query: 836  LVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQ--GKPRPELTWKKDGAEID----- 888
            L +E   P +   P  + +  ++++ E  ++V   Q  G P+P + WKK G  +      
Sbjct: 1023 LTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRY 1082

Query: 889  KNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIE 948
            K   N +  E   +I +  A+   +G+Y + V+ +K  ET S    +++      ++K +
Sbjct: 1083 KVSYNKQTGECKLVISMTFAD--DAGEYTIVVR-NKHGET-SASASLLEEADYELLMKSQ 1138

Query: 949  DVWGENVALTWTPPKDDGNAAITGYTIQKADKK-SMEWFTVIEHYHRTSATITELVIGNE 1007
                    +T    +        G+   + +K+   E   + +   + +  +   V   E
Sbjct: 1139 QEMLYQTQVTAFVQEPKVGETAPGFVYSEYEKEYEKEQALIRKKMAKDTVVVRTYVEDQE 1198

Query: 1008 YYFRVFSENMCGLSEDATM-TKESAVIARDGKIYKNPVYEDFDFSEAPM--FTQPLVNTY 1064
            ++   F E +    E   + T    ++  DG+     +  D   SEA    F   + N  
Sbjct: 1199 FHISSFEERLIKEIEYRIIKTTLEELLEEDGE---EKMAVDISESEAVESGFDSRIKNYR 1255

Query: 1065 AIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRM-FSNQGVCTLEIRKPSPYDGGT 1123
             + G   T +C + G P PKI W K+   I    RY+M F   G  +L I    P D G 
Sbjct: 1256 ILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPEDEGI 1315

Query: 1124 YCCKAVNDLGTVEIECKLEVKVIA 1147
            Y   A N  G      KL V+  A
Sbjct: 1316 YTAFASNIKGNAICSGKLYVEPAA 1339



 Score = 57.0 bits (136), Expect = 1e-07
 Identities = 43/167 (25%), Positives = 72/167 (43%), Gaps = 11/167 (6%)

Query: 370 TKQLEDTTAYCGERVELECEVSEDDA-NVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIE 428
           T+ L+      G     E  +S      V WF++G+ I        +I     +  L I 
Sbjct: 9   TQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKLTIP 68

Query: 429 GATKADAAEYSVMTTGGQSSAKLSVDL------KPLKILTPLTDQTVNLGKEICLKCEIS 482
             TKA++  YS+  T G   A  + +L       P   +  L   TV  G ++ L+  ++
Sbjct: 69  AVTKANSGRYSLKATNGSGQATSTAELLVKAETAPPNFVQRLQSMTVRQGSQVRLQVRVT 128

Query: 483 ENIPG---KWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDY 526
             IP    K+ ++G  +Q S   ++  +G ++ L+IA A  ED G Y
Sbjct: 129 -GIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTY 174



 Score = 56.6 bits (135), Expect = 1e-07
 Identities = 39/140 (27%), Positives = 56/140 (40%), Gaps = 9/140 (6%)

Query: 1010  FRVFSENMCGLSEDATM---TKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAI 1066
             F+   E +  +SE       T ES V  +       P+      S  P+    L +T   
Sbjct: 26506 FKSIHEKVSKISETKKSDQKTTESTVTRKTEPKAPEPI------SSKPVIVTGLQDTTVS 26559

Query: 1067  AGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCC 1126
             +   A       G P+P   W K+  AI    +Y++  ++G   LEI K    D G Y C
Sbjct: 26560 SDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTC 26619

Query: 1127  KAVNDLGTVEIECKLEVKVI 1146
                N  G+V   CKL +K I
Sbjct: 26620 TVKNSAGSVSSSCKLTIKAI 26639



 Score = 56.6 bits (135), Expect = 1e-07
 Identities = 74/348 (21%), Positives = 121/348 (34%), Gaps = 77/348 (22%)

Query: 872   GKPRPELTWKKDGAEIDKN-QINIRNSETDTIIFIRKAERSHSGKYD------------- 917
             G+PRP   W KDG  I +  +  +   +    + I K + S SG Y              
Sbjct: 26572 GEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSS 26631

Query: 918   --LQVKVDKFVETASIDIQIIDRPGPPQIVKIED------VWGENVALTWTPP------K 963
               L +K  K  E   +  Q      P +   +++      +  E + ++          K
Sbjct: 26632 CKLTIKAIKDTEAQKVSTQKTSEITPQKKAVVQEEISQKALRSEEIKMSEAKSQEKLALK 26691

Query: 964   DDGNAAITGYTIQKADKKSMEWFTVIEHYHRTS-------------ATITELVIGNEYYF 1010
             ++ +  +    ++K+   S+E   V E   +TS             A  T++ I NE   
Sbjct: 26692 EEASKVLISEEVKKSAATSLEKSIVHEEITKTSQASEEVRTHAEIKAFSTQMSI-NEGQR 26750

Query: 1011  RVFSENMCGLSE-----------------------DATMT------KESAVIARDGKIYK 1041
              V   N+ G ++                       D T+T      ++  ++    K  +
Sbjct: 26751 LVLKANIAGATDVKWVLNGVELTNSEEYRYGVSGSDQTLTIKQASHRDEGILTCISKTKE 26810

Query: 1042  NPVYEDFDF------SEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIV 1095
               V   +D       S+AP F     +     G N    C + G P P+I W KN + I 
Sbjct: 26811 GIVKCQYDLTLSKELSDAPAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPIS 26870

Query: 1096  DDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1143
                   +  ++ V +LEIR  S  D G Y  KA N  G       L V
Sbjct: 26871 ISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMV 26918



 Score = 54.7 bits (130), Expect = 5e-07
 Identities = 52/221 (23%), Positives = 77/221 (34%), Gaps = 45/221 (20%)

Query: 927  ETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWF 986
            +TA  D++++ RP P      E  W             DG   +  YT +          
Sbjct: 1426 QTARFDLKVVGRPMP------ETFWFH-----------DGQQIVNDYTHK---------- 1458

Query: 987  TVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYE 1046
             VI+     S  I      +   + V ++N  G S  + +    AV              
Sbjct: 1459 VVIKEDGTQSLIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAV-------------- 1504

Query: 1047 DFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDD--PRYRMFS 1104
              +    PMF + L N     G    +     GNP P I W+KN   IV    P+ R+  
Sbjct: 1505 --EHQVKPMFVEKLKNVNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEG 1562

Query: 1105 NQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVKV 1145
             +G   L+I      D   Y   A+N  G     CK+ V+V
Sbjct: 1563 TKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEV 1603



 Score = 51.2 bits (121), Expect = 6e-06
 Identities = 56/305 (18%), Positives = 122/305 (40%), Gaps = 22/305 (7%)

Query: 849   PRHLKQTYIRRVGEAVNLVIPFQ--GKPRPELTWKKDGAEID-KNQINIRNSETDTIIFI 905
             P  + Q   + + E  N++   +  G+P PE+ W K+   I   + ++I  S     + I
Sbjct: 26829 PAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEI 26888

Query: 906   RKAERSHSGKYDLQVKVDKFVETASIDIQIIDR-PGPPQIVKIEDVWGENVALTWTPPKD 964
             R A  S SGKY ++ K  +   +A+  + ++     P + V +      ++  +++    
Sbjct: 26889 RNASVSDSGKYTIKAKNFRGQCSATASLMVLPLVEEPSREVVLRTSGDTSLQGSFSSQSV 26948

Query: 965   DGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDA 1024
               +A+    +       S    T ++    ++ +++ +    E +  + S +  G+S   
Sbjct: 26949 QMSASKQEASFSSFSSSSASSMTEMKFASMSAQSMSSM---QESFVEMSSSSFMGISNMT 27005

Query: 1025  TMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAI-AGYNATLNCSVRGNPKP 1083
              +   ++ + + G                P   + L +  +I  G   T+ C+  G P P
Sbjct: 27006 QLESSTSKMLKAG------------IRGIPPKIEALPSDISIDEGKVLTVACAFTGEPTP 27053

Query: 1084  KITWM--KNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKL 1141
             ++TW     K+   +  R+ + +   + TL I      DGG Y     N+ G+      +
Sbjct: 27054 EVTWSCGGRKIHSQEQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNI 27113

Query: 1142  EVKVI 1146
              ++ I
Sbjct: 27114 HIRSI 27118



 Score = 49.7 bits (117), Expect = 2e-05
 Identities = 111/565 (19%), Positives = 201/565 (35%), Gaps = 77/565 (13%)

Query: 135  LQLKETFERHSRVYTFEMQIIKAKDNFAGNYRCEVTYKDKFDSCSFDLEVHESTGTTPNI 194
            L++ E +      YTF       + +   N   EV   D+  S     +V ES  +    
Sbjct: 3355 LEIAEAYPEDEGTYTFVASNAVGQVSSTANLSLEVQALDRQSSGK---DVRESAKSQAVA 3411

Query: 195  DIRSAFKRSGEGQEDAGELDFSGLLKRREVKQQEEEPQVDVWELLKNAKPSEYEKIAFQY 254
            D     + S   Q++     F G     EV+  E   Q  +      A   +  ++    
Sbjct: 3412 DSSFTKEESKISQKEIKS--FQGSSYEYEVQVFESVSQSSI----HTAASVQDTQLCHTA 3465

Query: 255  GITDLRGMLKRLKRMRREEKKSAAFAKILDPAYQVDKGGRVRFVVELADPK-LEVKWYKN 313
             ++ +    +  K   +E    A    +      V  G   +F+  L D   ++V W   
Sbjct: 3466 SLSQIAESTELSKECAKESTGEAPKIFLHLQDVTVKCGDTAQFLCVLKDDSFIDVTWTHE 3525

Query: 314  GQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEY----YVTAGDEKCSTELFVREPPIMV 369
            G +I  S +      G  + L I N Q+ D   Y    +   G+   S  L V   P  +
Sbjct: 3526 GAKIEESERLKQSQNGNIQFLTICNVQLVDQGLYSCIVHNDCGERTTSAVLSVEGAPESI 3585

Query: 370  TKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEG 429
                        ER+E E E+   + +  +    EE +   + +   ++     +L    
Sbjct: 3586 LH----------ERIEQEIEMEMKEFSSSFLSAEEEGLHSAELQLS-KINETLELL---- 3630

Query: 430  ATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCEISENIPG-- 487
                  +E  V  T   S  + +  +     +  +++  +++G    L   +   IP   
Sbjct: 3631 ------SESPVYPTKFDSEKEGTGPI----FIKEVSNADISMGDVATLSVTVI-GIPKPK 3679

Query: 488  -KWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYV-FAPDAYNVTLPAKVHVID 545
             +W  NG+ +  S   K V  G  H L+I     EDEG+Y   A + Y  T+ +    I+
Sbjct: 3680 IQWFFNGVLLTPSADYKFVFDGDDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKIN 3739

Query: 546  PPKIILDGLDADNTVTVIAGNKLRL-------------------------EIPISGEPPP 580
                  +G     T + +A +  +L                         E  + GEP P
Sbjct: 3740 SKG---EGHKDTETESAVAKSLEKLGGPCPPHFLKELKPIRCAQGLPAIFEYTVVGEPAP 3796

Query: 581  KAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVK 640
               W + +K +          +   S T +++  +R+DSG+Y    +N  GE+  + ++ 
Sbjct: 3797 TVTWFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGLYICKAENMLGESTCAAELL 3856

Query: 641  VV----DFPDPPV-APTVTEVGDDW 660
            V+    D  D P  A +  E  +D+
Sbjct: 3857 VLLEDTDMTDTPCKAKSTPEAPEDF 3881



 Score = 49.7 bits (117), Expect = 2e-05
 Identities = 96/424 (22%), Positives = 163/424 (38%), Gaps = 79/424 (18%)

Query: 739  PLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLID 798
            PLA+     LL  +   +  +     PPD I  +  +   ++   E      V  +DL+ 
Sbjct: 4160 PLALEEKQVLLKEEHSDNVVM-----PPDQIIESKREPVAIKKVQE------VQGRDLLS 4208

Query: 799  KTKFTITGLPTDAKIFVRV---KAVNAAGASE-PKYYSQPILVKEIIEPPKIRI---PRH 851
            K    ++G+P + ++ +++   +A+ AA ASE P  +S+ +   E +E   + I   PRH
Sbjct: 4209 KESL-LSGIPEEQRLNLKIQICRALQAAVASEQPGLFSEWLRNIEKVEVEAVNITQEPRH 4267

Query: 852  LKQTYI----RRVGEAVNLVIPFQGKPRPELTWKKDGA--EIDKNQINIRNSETDTIIFI 905
            +   Y+    + V E V ++I         L  +   A   I   +I+I  +E   I   
Sbjct: 4268 IMCMYLVTSAKSVTEEVTIIIEDVDPQMANLKMELRDALCAIIYEEIDILTAEGPRI--- 4324

Query: 906  RKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVA-----LTWT 960
                     K  LQ ++D F  +  ++           ++  E+V   NV      L  T
Sbjct: 4325 -----QQGAKTSLQEEMDSFSGSQKVEPITEPEVESKYLISTEEVSYFNVQSRVKYLDAT 4379

Query: 961  PPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGL 1020
            P      +A+       +D+K  E     E    +S+                     G 
Sbjct: 4380 PVTKGVASAVV------SDEKQDESLKPSEEKEESSSE-------------------SGT 4414

Query: 1021 SEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGN 1080
             E AT+  + A    +G + K          + PM   PLV+T +  G    L  S+  N
Sbjct: 4415 EEVATVKIQEA----EGGLIKE---------DGPMIHTPLVDTVSEEGDIVHLTTSIT-N 4460

Query: 1081 PKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDG-GTYCCKAVNDLGTVEIEC 1139
             K ++ W      +  D +++   +Q   TL I K +  D  G Y C+A+ND G      
Sbjct: 4461 AK-EVNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDHQGEYVCEALNDSGKTATSA 4519

Query: 1140 KLEV 1143
            KL V
Sbjct: 4520 KLTV 4523



 Score = 48.9 bits (115), Expect = 3e-05
 Identities = 59/283 (20%), Positives = 97/283 (34%), Gaps = 70/283 (24%)

Query: 861  GEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQV 920
            GE+V L     G P P +TW ++  +I+                                
Sbjct: 911  GESVTLECHISGYPSPTVTWYREDYQIE-------------------------------- 938

Query: 921  KVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADK 980
                    +SID QI  + G  +++  E    ++   T +   + G  + + Y   +   
Sbjct: 939  --------SSIDFQITFQSGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQ--- 987

Query: 981  KSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIY 1040
                   V E + + +  +TE     E   + F E+   +  D ++T+E A        Y
Sbjct: 988  -------VSEEFEKETTAVTEKFTTEE---KRFVESRDVVMTDTSLTEEQAGPGEPAAPY 1037

Query: 1041 KNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRY 1100
                            T+P+V    + G +    C V GNPKP + W K+ V +    RY
Sbjct: 1038 --------------FITKPVVQKL-VEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRY 1082

Query: 1101 RMFSNQ--GVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKL 1141
            ++  N+  G C L I      D G Y     N  G       L
Sbjct: 1083 KVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL 1125



 Score = 47.8 bits (112), Expect = 6e-05
 Identities = 61/279 (21%), Positives = 101/279 (36%), Gaps = 22/279 (7%)

Query: 291  KGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVT 350
            +G   RF   ++   L+V WY   ++I+PS  +          L I      D+  Y   
Sbjct: 3312 EGQPARFQCRVSGTDLKVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFV 3371

Query: 351  A----GDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEI 406
            A    G    +  L +    +      +D       +   +   +++++ +    + +EI
Sbjct: 3372 ASNAVGQVSSTANLSLEVQALDRQSSGKDVRESAKSQAVADSSFTKEESKI----SQKEI 3427

Query: 407  IPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDL----------K 456
                 S Y   V+  + +      T A   +  +  T   S    S +L          +
Sbjct: 3428 KSFQGSSYEYEVQVFESVSQSSIHTAASVQDTQLCHTASLSQIAESTELSKECAKESTGE 3487

Query: 457  PLKILTPLTDQTVNLGKEICLKCEISEN--IPGKWTKNGLPVQESDRLKVVHKGRIHKLV 514
              KI   L D TV  G      C + ++  I   WT  G  ++ES+RLK    G I  L 
Sbjct: 3488 APKIFLHLQDVTVKCGDTAQFLCVLKDDSFIDVTWTHEGAKIEESERLKQSQNGNIQFLT 3547

Query: 515  IANALTEDEGDY--VFAPDAYNVTLPAKVHVIDPPKIIL 551
            I N    D+G Y  +   D    T  A + V   P+ IL
Sbjct: 3548 ICNVQLVDQGLYSCIVHNDCGERTTSAVLSVEGAPESIL 3586



 Score = 47.4 bits (111), Expect = 8e-05
 Identities = 28/96 (29%), Positives = 44/96 (45%), Gaps = 2/96 (2%)

Query: 1051 SEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDD--PRYRMFSNQGV 1108
            ++AP FTQPL +   + G  AT    + G P P+++W ++   I     P  ++  + G 
Sbjct: 3    TQAPTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGR 62

Query: 1109 CTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVK 1144
              L I   +  + G Y  KA N  G      +L VK
Sbjct: 63   AKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVK 98



 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 36/105 (34%), Positives = 48/105 (45%), Gaps = 4/105 (3%)

Query: 537 LPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSG 596
           +PA V +   P  ++ GL     VTVI G  + LE  ISG P P   W R D  I E S 
Sbjct: 886 VPAPVEIPVTPPTLVSGL---KNVTVIEGESVTLECHISGYPSPTVTWYREDYQI-ESSI 941

Query: 597 RIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKV 641
             +       + L+I  A  +DSG +  +  NEAG    S  + V
Sbjct: 942 DFQITFQSGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAV 986



 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 29/93 (31%), Positives = 42/93 (45%), Gaps = 3/93 (3%)

Query: 1054  PMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIV---DDPRYRMFSNQGVCT 1110
             P FT PL N  A  G N     ++  +P+P +TW K+   I    +D +Y   S++G+  
Sbjct: 25385 PEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQ 25444

Query: 1111  LEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1143
             L I   +  D   Y   A N  G    + KL V
Sbjct: 25445 LTINSVTTDDDAEYTVVARNKYGEDSCKAKLTV 25477



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 34/107 (31%), Positives = 47/107 (43%), Gaps = 4/107 (3%)

Query: 1041 KNPVYEDFDFSE----APMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVD 1096
            ++PVY     SE     P+F + + N     G  ATL+ +V G PKPKI W  N V +  
Sbjct: 3632 ESPVYPTKFDSEKEGTGPIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTP 3691

Query: 1097 DPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1143
               Y+   +    +L I      D G Y C A ND G       L++
Sbjct: 3692 SADYKFVFDGDDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKI 3738



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 25/93 (26%), Positives = 42/93 (45%)

Query: 1053 APMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLE 1112
            AP+  + +       G+ A   C ++  P  +  W K    I +  +  + S++ + +LE
Sbjct: 4528 APVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLE 4587

Query: 1113 IRKPSPYDGGTYCCKAVNDLGTVEIECKLEVKV 1145
            I +    D G Y CKA N+ G+V     L V V
Sbjct: 4588 ILRTQVVDCGEYTCKASNEYGSVSCTATLTVTV 4620



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 30/96 (31%), Positives = 39/96 (40%), Gaps = 3/96 (3%)

Query: 1054 PMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSN-QGVCTLE 1112
            P F + L       G  A    +V G P P +TW K    +     Y +  N  G  T  
Sbjct: 3767 PHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFI 3826

Query: 1113 IRKPSPYDGGTYCCKAVNDLGTVEIECKLEVKVIAQ 1148
            +  P   D G Y CKA N LG  E  C  E+ V+ +
Sbjct: 3827 VNDPQREDSGLYICKAENMLG--ESTCAAELLVLLE 3860



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 29/100 (29%), Positives = 49/100 (49%), Gaps = 5/100 (5%)

Query: 939   PGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEH--YHRTS 996
             P  P    + +V  ++  +TW  P D G   IT Y ++K +  S  W  V +   +  T 
Sbjct: 10707 PDAPDQPIVTEVTKDSALVTWNKPHDGGKP-ITNYILEKRETMSKRWARVTKDPIHPYTK 10765

Query: 997   ATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARD 1036
               + +L+ G +Y FRV +EN  G+ + +  +K   V A+D
Sbjct: 10766 FRVPDLLEGCQYEFRVSAENEIGIGDPSPPSK--PVFAKD 10803



 Score = 45.1 bits (105), Expect = 4e-04
 Identities = 120/582 (20%), Positives = 208/582 (35%), Gaps = 92/582 (15%)

Query: 341  MTDDSEYYVTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDA-NVKW 399
            MTD S     AG  + +   F+ +P  +V K +E      G  V   C+V  +   +V W
Sbjct: 1018 MTDTSLTEEQAGPGEPAAPYFITKP--VVQKLVE------GGSVVFGCQVGGNPKPHVYW 1069

Query: 400  FKNGEEIIPGPKSRYRIRVEGKKHI----LIIEGATKADAAEYSVMTTG--GQSSAKLSV 453
             K+G  +  G    YR +V   K      L+I      DA EY+++     G++SA  S+
Sbjct: 1070 KKSGVPLTTG----YRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL 1125

Query: 454  DLKPLKILTPLTDQTVNLGKEICL---KCEISENIPGKWTKNGLPVQESDRLKVVHKGRI 510
              +    L   + Q +    ++     + ++ E  PG +  +    +      ++ K   
Sbjct: 1126 LEEADYELLMKSQQEMLYQTQVTAFVQEPKVGETAPG-FVYSEYEKEYEKEQALIRKKMA 1184

Query: 511  HKLVIANALTEDEGDYVFAPDA----------YNVTLPAKVHVIDPPKIILD-------- 552
               V+     ED+  ++ + +              TL   +      K+ +D        
Sbjct: 1185 KDTVVVRTYVEDQEFHISSFEERLIKEIEYRIIKTTLEELLEEDGEEKMAVDISESEAVE 1244

Query: 553  -GLDAD-NTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDS-STL 609
             G D+      ++ G  +     +SG P PK  W +  K I  G  R + +   D  ++L
Sbjct: 1245 SGFDSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGE-RYQMDFLQDGRASL 1303

Query: 610  VIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPA 669
             I +   +D G+Y     N  G A  S K+ V      P AP    +G    I   EP  
Sbjct: 1304 RIPVVLPEDEGIYTAFASNIKGNAICSGKLYV-----EPAAP----LGAPTYIPTLEP-- 1352

Query: 670  YDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISK 729
                       + R +  S R +  +          P +M        R+     +  + 
Sbjct: 1353 -----------VSRIRSLSPRSVSRSPIRMSPARMSPARMSPARMSPARMSPGRRLEETD 1401

Query: 730  PSMPSRPFVPLAVTSPPTLLTVDSVT---DTTVTMRWRPPD---HIGAAGLDGYVLEYCF 783
             S   R + P+ V  P +   ++  T   D  V  R  P     H G   ++ Y  +   
Sbjct: 1402 ESQLERLYKPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVI 1461

Query: 784  --EGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEII 841
              +GT+  I+      D  ++T+              A N AG S     S  + V+ + 
Sbjct: 1462 KEDGTQSLIIVPATPSDSGEWTVV-------------AQNRAGRSS---ISVILTVEAVE 1505

Query: 842  EPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKD 883
               K      LK   I+  G  + + +   G P P++ W K+
Sbjct: 1506 HQVKPMFVEKLKNVNIKE-GSRLEMKVRATGNPNPDIVWLKN 1546



 Score = 44.7 bits (104), Expect = 5e-04
 Identities = 62/284 (21%), Positives = 105/284 (36%), Gaps = 51/284 (17%)

Query: 876  PELT--WKKDGAEID-KNQINIRNSETDTIIFIRKAERSHSGKYDL----QVKVDK-FVE 927
            P++T  W KD  E+   ++I I+  +    + I     S +GKY +     V   K FVE
Sbjct: 3038 PDITVQWMKDDQELQITDRIKIQKEKYVHRLLIPSTRMSDAGKYTVVAGGNVSTAKLFVE 3097

Query: 928  TASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNA------AITGYTIQKADKK 981
               + I+ I +       +++ +  +   + +   +DD +A          + +Q+  K 
Sbjct: 3098 GRDVRIRSIKK-------EVQVIEKQRAVVEFEVNEDDVDAHWYKDGIEINFQVQERHK- 3149

Query: 982  SMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYK 1041
                + V    HR   + T      EY F V   N   ++                 +Y 
Sbjct: 3150 ----YVVERRIHRMFISETRQSDAGEYTF-VAGRNRSSVT-----------------LYV 3187

Query: 1042 NPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYR 1101
            N         E P   Q L      +G  A     + G P+PKI+W K +  +    + +
Sbjct: 3188 NA-------PEPPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCK 3240

Query: 1102 MFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVKV 1145
               +    TL + +  P D   Y C+A ND G       L V+V
Sbjct: 3241 FLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEV 3284



 Score = 44.3 bits (103), Expect = 7e-04
 Identities = 29/98 (29%), Positives = 51/98 (52%), Gaps = 1/98 (1%)

Query: 559 TVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDD 618
           ++TV  G+++RL++ ++G P P   + R D A ++ S   +     D  +L+I  A  +D
Sbjct: 112 SMTVRQGSQVRLQVRVTGIPTPVVKFYR-DGAEIQSSLDFQISQEGDLYSLLIAEAYPED 170

Query: 619 SGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEV 656
           SG Y +N  N  G A ++ ++ V    + P   T T V
Sbjct: 171 SGTYSVNATNSVGRATSTAELLVQGEEEVPAKKTKTIV 208



 Score = 44.3 bits (103), Expect = 7e-04
 Identities = 64/320 (20%), Positives = 110/320 (34%), Gaps = 40/320 (12%)

Query: 340   QMTDDSEYYVTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEV-SEDDANVK 398
             Q T + +Y      E  S + F  +    +T ++      CG+       V S+  A VK
Sbjct: 26048 QKTSERKY------EVLSQQPFTLDHAPRITLRMRSHRVPCGQNTRFILNVQSKPTAEVK 26101

Query: 399   WFKNGEEIIPGPKSRYRIRVEGKKHILIIEGAT-------------KADAAEYSVM-TTG 444
             W+ NG E+    K  Y     G   + I++  T             K +A++Y+ +  TG
Sbjct: 26102 WYHNGVELQESSKIHYT-NTSGVLTLEILDCHTDDSGTYRAVCTNYKGEASDYATLDVTG 26160

Query: 445   GQSSAKLSV---DLKPLKILTPLTDQTVNLGKEICLKCEISENIPGKWTKNGLPVQESDR 501
             G  +   S    +  P  +   LT              E+  +   +  K+ +       
Sbjct: 26161 GDYTTYASQRRDEEVPRSVFPELTRTEAYAVSSFKKTSEMEASSSVREVKSQMTETRESL 26220

Query: 502   LKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVT 561
                 H       + + AL E   +          TL A++            L    ++T
Sbjct: 26221 SSYEHSASAE--MKSAALEEKSLEEKSTTRKIKTTLAARI------------LTKPRSMT 26266

Query: 562   VIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGV 621
             V  G   R      GEP P   W R  + ++  S R +  +    ST  I   +  D G 
Sbjct: 26267 VYEGESARFSCDTDGEPVPTVTWLRKGQ-VLSTSARHQVTTTKYKSTFEISSVQASDEGN 26325

Query: 622   YHINLKNEAGEAHASIKVKV 641
             Y + ++N  G+  A   + +
Sbjct: 26326 YSVVVENSEGKQEAEFTLTI 26345



 Score = 43.9 bits (102), Expect = 9e-04
 Identities = 94/440 (21%), Positives = 160/440 (36%), Gaps = 71/440 (16%)

Query: 271  REEKKSAAFAKILDPAYQVDKGGRVRFVVELAD-PKLEVKWYKNGQEIRPSTKYIFEHKG 329
            ++EK+        +P  +V +G   RF   +   P+ +V WY NGQ IR S ++   + G
Sbjct: 1789 QKEKQKPDIVLYPEPV-RVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRVRYDG 1847

Query: 330  CQRILFINNCQMTDDSEYYVTAG------DEKCSTELFVREP------------------ 365
                L I +C+  D  E  VTA       + K   E+  RE                   
Sbjct: 1848 I-HYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQREDFRSVLRRAPEPRPEFHVH 1906

Query: 366  --------------PIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGE-----EI 406
                          P+  T+  E       ER+  E    E +     FK        E 
Sbjct: 1907 EPGKLQFEVQKVDRPVDTTETKEVVKLKRAERITHEKVPEESEELRSKFKRRTEEGYYEA 1966

Query: 407  IPGPKSRYRIRVEGKKHIL-------------IIEGATKADAAEYSV-MTTGGQSSAKLS 452
            I   + + R + E  + +L             + E   KA A E  + + T      +LS
Sbjct: 1967 ITAVELKSRKKDESYEELLRKTKDELLHWTKELTEEEKKALAEEGKITIPTFKPDKIELS 2026

Query: 453  VDLKPLKILTPLTDQTVNLGKEICLKCEI--SENIPGKWTKNGLPVQESDRLK-VVHKGR 509
              ++  KI   +  QTV  G +   +  +    +   +W KNG+ ++ SDR+     +  
Sbjct: 2027 PSMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDN 2086

Query: 510  IHKLVIANALTEDEGDYVFAPDAYNVTLPAKVH---VIDPPKIILDGLDADNTVTVIAGN 566
            + +LVI +   ED    +    A N+      H   ++   ++I    +  + V      
Sbjct: 2087 VCELVIRDVTAEDSASIMV--KAINIAGETSSHAFLLVQAKQLITFTQELQDVVAKEKDT 2144

Query: 567  KLRLEIPISGEPPPKAMWSRGDKAIMEGSG-RIRTE-SYPDSSTLVIDIAERDDSGVYHI 624
                E   S EP  K  W +    + EG   R+ ++      S L ID ++ +D     +
Sbjct: 2145 MATFECETS-EPFVKVKWYKDGMEVHEGDKYRMHSDRKVHFLSILTIDTSDAEDYSCVLV 2203

Query: 625  NLKNEAGEAHASIKVKVVDF 644
              +N    A   ++  VV+F
Sbjct: 2204 EDENVKTTAKLIVEGAVVEF 2223



 Score = 43.9 bits (102), Expect = 9e-04
 Identities = 26/79 (32%), Positives = 37/79 (46%), Gaps = 1/79 (1%)

Query: 1066 IAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYC 1125
            + G  A   C V G P+PK+ W  N   I    R+R+    G+  L+I     YD G   
Sbjct: 1807 LEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRV-RYDGIHYLDIVDCKSYDTGEVK 1865

Query: 1126 CKAVNDLGTVEIECKLEVK 1144
              A N  G +E + KLE++
Sbjct: 1866 VTAENPEGVIEHKVKLEIQ 1884



 Score = 43.9 bits (102), Expect = 9e-04
 Identities = 59/286 (20%), Positives = 102/286 (35%), Gaps = 24/286 (8%)

Query: 861   GEAVNLVIPFQGKPRPELTWKKDGAEI-DKNQINIRNSETDTIIFIRKAERSHSGKYDLQ 919
             G+    ++  Q KP  E+ W  +G E+ + ++I+  N+     + I       SG Y  +
Sbjct: 26083 GQNTRFILNVQSKPTAEVKWYHNGVELQESSKIHYTNTSGVLTLEILDCHTDDSGTY--R 26140

Query: 920   VKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKAD 979
                  +   AS D   +D  G            E V  +  P      A    Y +    
Sbjct: 26141 AVCTNYKGEAS-DYATLDVTGGDYTTYASQRRDEEVPRSVFPELTRTEA----YAVSSFK 26195

Query: 980   KKS-MEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGK 1038
             K S ME  + +       + +TE             E++      A+   +SA +     
Sbjct: 26196 KTSEMEASSSVRE---VKSQMTET-----------RESLSSYEHSASAEMKSAALEEKSL 26241

Query: 1039  IYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDP 1098
               K+   +      A + T+P   T    G +A  +C   G P P +TW++    +    
Sbjct: 26242 EEKSTTRKIKTTLAARILTKPRSMT-VYEGESARFSCDTDGEPVPTVTWLRKGQVLSTSA 26300

Query: 1099  RYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVK 1144
             R+++ + +   T EI      D G Y     N  G  E E  L ++
Sbjct: 26301 RHQVTTTKYKSTFEISSVQASDEGNYSVVVENSEGKQEAEFTLTIQ 26346



 Score = 43.5 bits (101), Expect = 0.001
 Identities = 61/263 (23%), Positives = 104/263 (39%), Gaps = 35/263 (13%)

Query: 286   AYQVDKGGRVRFVVEL-ADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDD 344
             +++V  G   RF++ + + P  EVKWY NG E++ S+K  + +      L I +C  TDD
Sbjct: 26077 SHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESSKIHYTNTSGVLTLEILDCH-TDD 26135

Query: 345   SEYY------------------VTAGD-EKCSTELFVREPPIMVTKQLEDTTAYCGERVE 385
             S  Y                  VT GD    +++    E P  V  +L  T AY     +
Sbjct: 26136 SGTYRAVCTNYKGEASDYATLDVTGGDYTTYASQRRDEEVPRSVFPELTRTEAYAVSSFK 26195

Query: 386   LECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGG 445
                E+ E  ++V+  K+         +  R  +   +H      + +  +A     +   
Sbjct: 26196 KTSEM-EASSSVREVKS-------QMTETRESLSSYEH----SASAEMKSAALEEKSLEE 26243

Query: 446   QSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCEI-SENIPG-KWTKNGLPVQESDRLK 503
             +S+ +        +ILT     TV  G+     C+   E +P   W + G  +  S R +
Sbjct: 26244 KSTTRKIKTTLAARILTKPRSMTVYEGESARFSCDTDGEPVPTVTWLRKGQVLSTSARHQ 26303

Query: 504   VVHKGRIHKLVIANALTEDEGDY 526
             V          I++    DEG+Y
Sbjct: 26304 VTTTKYKSTFEISSVQASDEGNY 26326



 Score = 43.1 bits (100), Expect = 0.002
 Identities = 41/170 (24%), Positives = 67/170 (39%), Gaps = 16/170 (9%)

Query: 489  WTKNGLPVQESDRLKVVHK-GRIHKLVIANALTEDEGDYVFAPD--------AYNVTLPA 539
            W  +G  +      KVV K      L+I  A   D G++             +  +T+ A
Sbjct: 1444 WFHDGQQIVNDYTHKVVIKEDGTQSLIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEA 1503

Query: 540  KVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGS-GRI 598
              H + P  +     +    V +  G++L +++  +G P P  +W +    I+     +I
Sbjct: 1504 VEHQVKPMFV-----EKLKNVNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKI 1558

Query: 599  RTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKV-VDFPDP 647
            R E     + L ID     DS  Y     N+AG      KV V V+F +P
Sbjct: 1559 RIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEVEFAEP 1608



 Score = 43.1 bits (100), Expect = 0.002
 Identities = 67/327 (20%), Positives = 116/327 (35%), Gaps = 65/327 (19%)

Query: 369   VTKQLEDTTAYCGERVELECEVSEDDAN--VKWFKNGEEIIPGPKSRYRIRVEGKKHILI 426
             V+ Q+       G  V+  C++   D +  V W+    ++    K  Y I  E    IL 
Sbjct: 25265 VSGQIMHAVGEEGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEK--YEITYEDGVAILY 25322

Query: 427   IEGATKADAAEY--SVMTTGGQSSAKLSVDLK---------------------------- 456
             ++  TK D   Y   V+   G+ S+   + +K                            
Sbjct: 25323 VKDITKLDDGTYRCKVVNDYGEDSSYAELFVKGVREVYDYYCRRTMKKIKRRTDTMRLLE 25382

Query: 457   -PLKILTPLTDQTVNLGKEICLKCEISENIPGK--WTKNGLPVQESDRLKVV----HKGR 509
              P +   PL ++T  +G+ +     I+ +      W K+G  ++  D  K       KG 
Sbjct: 25383 RPPEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKG- 25441

Query: 510   IHKLVIANALTEDEGDYV------FAPDAYNVTLPAKVHVIDPP---------KIILDGL 554
             +++L I +  T+D+ +Y       +  D+    L   +H   PP         K +L   
Sbjct: 25442 LYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVTLH--PPPTDSTLRPMFKRLLANA 25499

Query: 555   DADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIA 614
             +         G  +  EI +SG PPP   W +  + +  G          D   L I   
Sbjct: 25500 ECQE------GQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALHIRDT 25553

Query: 615   ERDDSGVYHINLKNEAGEAHASIKVKV 641
               +D+G Y +   N AG       ++V
Sbjct: 25554 LPEDTGYYRVTATNTAGSTSCQAHLQV 25580



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 33/111 (29%), Positives = 46/111 (41%), Gaps = 5/111 (4%)

Query: 1028 KESAVIARDGKI----YKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKP 1083
            +E   +A +GKI    +K    E     EAP   + + +     G +A     V G P P
Sbjct: 2002 EEKKALAEEGKITIPTFKPDKIELSPSMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDP 2061

Query: 1084 KITWMKNKVAIVDDPR-YRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLG 1133
            +  W KN V I    R Y  +    VC L IR  +  D  +   KA+N  G
Sbjct: 2062 ECEWYKNGVKIERSDRIYWYWPEDNVCELVIRDVTAEDSASIMVKAINIAG 2112



 Score = 42.4 bits (98), Expect = 0.003
 Identities = 75/321 (23%), Positives = 117/321 (36%), Gaps = 33/321 (10%)

Query: 838  KEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQ-GKPRPELTWKKDGAEIDKNQINIRN 896
            K  +E   +RI    K+    +V E    V+ F+  +   +  W KDG EI+        
Sbjct: 3093 KLFVEGRDVRIRSIKKEV---QVIEKQRAVVEFEVNEDDVDAHWYKDGIEINFQVQERHK 3149

Query: 897  SETDTII---FIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGE 953
               +  I   FI +  +S +G+Y      ++   T       ++ P PPQ+++      E
Sbjct: 3150 YVVERRIHRMFISETRQSDAGEYTFVAGRNRSSVTL-----YVNAPEPPQVLQ------E 3198

Query: 954  NVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEY---YF 1010
               +T    K     A+    I    +  + W+   E    T      L  G EY     
Sbjct: 3199 LQPVTVQSGKPARFCAV----ISGRPQPKISWYKE-EQLLSTGFKCKFLHDGQEYTLLLI 3253

Query: 1011 RVFSENM----CGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAI 1066
              F E+     C    D  +   SA ++ +     +P  E   +   P    PL +T   
Sbjct: 3254 EAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMPVYP--PAIITPLQDTVTS 3311

Query: 1067 AGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCC 1126
             G  A   C V G    K++W      I     +RM   +    LEI +  P D GTY  
Sbjct: 3312 EGQPARFQCRVSGTDL-KVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTF 3370

Query: 1127 KAVNDLGTVEIECKLEVKVIA 1147
             A N +G V     L ++V A
Sbjct: 3371 VASNAVGQVSSTANLSLEVQA 3391



 Score = 40.0 bits (92), Expect = 0.013
 Identities = 44/211 (20%), Positives = 95/211 (45%), Gaps = 28/211 (13%)

Query: 270  RREEKKSAAFAKILDPAYQVD-------KGGRVRFVVELAD-PKLEVKWYKNGQEIRP-- 319
            R EE   +   ++  P + +        +G   RF +++   P  E  W+ +GQ+I    
Sbjct: 1396 RLEETDESQLERLYKPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDY 1455

Query: 320  STKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTELFV--------REPPIMVTK 371
            + K + +  G Q ++ +     +D  E+ V A +    + + V         +   M  +
Sbjct: 1456 THKVVIKEDGTQSLIIVP-ATPSDSGEWTVVAQNRAGRSSISVILTVEAVEHQVKPMFVE 1514

Query: 372  QLEDTTAYCGERVELECEVSED-DANVKWFKNGEEIIPGPKSRY-RIRVEGKK--HILII 427
            +L++     G R+E++   + + + ++ W KN + I+P    +Y +IR+EG K    L I
Sbjct: 1515 KLKNVNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVP---HKYPKIRIEGTKGEAALKI 1571

Query: 428  EGATKADAAEY--SVMTTGGQSSAKLSVDLK 456
            +     D+A Y  + +   G+ + +  V+++
Sbjct: 1572 DSTVSQDSAWYTATAINKAGRDTTRCKVNVE 1602



 Score = 39.7 bits (91), Expect = 0.017
 Identities = 25/98 (25%), Positives = 37/98 (37%)

Query: 1046  EDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSN 1105
             + F    AP  T  + +     G N     +V+  P  ++ W  N V + +  +    + 
Sbjct: 26061 QPFTLDHAPRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESSKIHYTNT 26120

Query: 1106  QGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1143
              GV TLEI      D GTY     N  G       L+V
Sbjct: 26121 SGVLTLEILDCHTDDSGTYRAVCTNYKGEASDYATLDV 26158



 Score = 39.3 bits (90), Expect = 0.022
 Identities = 58/327 (17%), Positives = 107/327 (32%), Gaps = 45/327 (13%)

Query: 861  GEAVNLVIPFQGKPRPELTWKKDGAEIDKN---QINIRNSETDTIIFIRKAERSHSGKYD 917
            G+     +   G+P PE  W  DG +I  +   ++ I+   T ++I +  A  S SG++ 
Sbjct: 1425 GQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLIIV-PATPSDSGEWT 1483

Query: 918  L--QVKVDKFVETASIDIQIIDRPGPPQIV----------------KIEDVWGENVALTW 959
            +  Q +  +   +  + ++ ++    P  V                K+      N  + W
Sbjct: 1484 VVAQNRAGRSSISVILTVEAVEHQVKPMFVEKLKNVNIKEGSRLEMKVRATGNPNPDIVW 1543

Query: 960  TPPKD------------DGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNE 1007
                D            +G        I     +   W+T     ++     T   +  E
Sbjct: 1544 LKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATA-INKAGRDTTRCKVNVE 1602

Query: 1008 YYFR--------VFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQP 1059
              F         +         E A    E   +    + ++     D +  + P F + 
Sbjct: 1603 VEFAEPEPERKLIIPRGTYRAKEIAAPELEPLHLRYGQEQWEEGDLYDKEKQQKPFFKKK 1662

Query: 1060 LVNTYAIAGYNATLNCSVR--GNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPS 1117
            L +        A   C +   G+P   + W+ +   +    R RM +  G C+L+     
Sbjct: 1663 LTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRMINEFGYCSLDYGVAY 1722

Query: 1118 PYDGGTYCCKAVNDLGTVEIECKLEVK 1144
              D G   C+A N  GT      L VK
Sbjct: 1723 SRDSGIITCRATNKYGTDHTSATLIVK 1749



 Score = 38.9 bits (89), Expect = 0.028
 Identities = 44/162 (27%), Positives = 69/162 (42%), Gaps = 13/162 (8%)

Query: 304 PKLEVKWYKNGQEIRPST--KYIFEHKGCQRILFINNCQMTDDSEYYVTA----GDEKCS 357
           P  EV W+++GQ I  ST           +  L I      +   Y + A    G    +
Sbjct: 33  PVPEVSWFRDGQVISTSTLPGVQISFSDGRAKLTIPAVTKANSGRYSLKATNGSGQATST 92

Query: 358 TELFVR---EPPIMVTKQLEDTTAYCGERVELECEVSE-DDANVKWFKNGEEIIPGPKSR 413
            EL V+    PP  V ++L+  T   G +V L+  V+      VK++++G EI       
Sbjct: 93  AELLVKAETAPPNFV-QRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEI--QSSLD 149

Query: 414 YRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDL 455
           ++I  EG  + L+I  A   D+  YSV  T     A  + +L
Sbjct: 150 FQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAEL 191



 Score = 38.1 bits (87), Expect = 0.048
 Identities = 38/173 (21%), Positives = 68/173 (39%), Gaps = 11/173 (6%)

Query: 362  VREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGK 421
            ++E   M+   L DT +  G+ V L   ++       +F+N  +++P  + +++   +  
Sbjct: 4430 IKEDGPMIHTPLVDTVSEEGDIVHLTTSITNAKEVNWYFEN--KLVPSDE-KFKCLQDQN 4486

Query: 422  KHILIIEGATKAD-AAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVN-----LGKEI 475
             + L+I+     D   EY             S  L  +K   P+  + +      LG   
Sbjct: 4487 TYTLVIDKVNTEDHQGEYVCEALNDSGKTATSAKLTVVKRAAPVIKRKIEPLEVALGHLA 4546

Query: 476  CLKCEISE--NIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDY 526
               CEI    N+  +W K G  + ESD+  +     I  L I      D G+Y
Sbjct: 4547 KFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEY 4599



 Score = 38.1 bits (87), Expect = 0.048
 Identities = 27/98 (27%), Positives = 41/98 (41%), Gaps = 3/98 (3%)

Query: 1049  DFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGV 1108
             D +  PMF + L N     G +      V G P P + W K+   +   P   +  ++G+
Sbjct: 25485 DSTLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEII-HEGL 25543

Query: 1109  --CTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVK 1144
                 L IR   P D G Y   A N  G+   +  L+V+
Sbjct: 25544 DYYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQVE 25581



 Score = 37.7 bits (86), Expect = 0.063
 Identities = 26/83 (31%), Positives = 34/83 (40%), Gaps = 5/83 (6%)

Query: 289   VDKGGRVRFVVELAD-PKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEY 347
             V  G  VRF   +   P    KW  +G EI+    Y  E      +L I NC   D  EY
Sbjct: 11217 VKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEY 11276

Query: 348   YVT----AGDEKCSTELFVREPP 366
              +T    AG +  +  L V + P
Sbjct: 11277 QITVSNAAGSKTVAVHLTVLDVP 11299



 Score = 37.7 bits (86), Expect = 0.063
 Identities = 19/65 (29%), Positives = 31/65 (47%)

Query: 1084  KITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1143
             ++TW      + +  +Y +    GV  L ++  +  D GTY CK VND G      +L V
Sbjct: 25294 QVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTYRCKVVNDYGEDSSYAELFV 25353

Query: 1144  KVIAQ 1148
             K + +
Sbjct: 25354 KGVRE 25358



 Score = 37.0 bits (84), Expect = 0.11
 Identities = 25/94 (26%), Positives = 40/94 (42%), Gaps = 1/94 (1%)

Query: 1054 PMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYR-MFSNQGVCTLE 1112
            P+F    V+   + G  A  +  V G P P+  W  +   IV+D  ++ +    G  +L 
Sbjct: 1411 PVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLI 1470

Query: 1113 IRKPSPYDGGTYCCKAVNDLGTVEIECKLEVKVI 1146
            I   +P D G +   A N  G   I   L V+ +
Sbjct: 1471 IVPATPSDSGEWTVVAQNRAGRSSISVILTVEAV 1504



 Score = 36.2 bits (82), Expect = 0.18
 Identities = 45/250 (18%), Positives = 92/250 (36%), Gaps = 31/250 (12%)

Query: 880  WKKDGAEIDKN-QINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDR 938
            W KDG EI  + + +I+      I+ I+KA+    G+Y      DK     +++ ++I  
Sbjct: 5389 WFKDGEEIVPSPKYSIKADGLRRILKIKKADLKDKGEYVCDCGTDKTKANVTVEARLIKV 5448

Query: 939  PGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSAT 998
              P   V++      +  +  + P   G   + G  +                   T++ 
Sbjct: 5449 EKPLYGVEVFVGETAHFEIELSEPDVHGQWKLKGQPL-------------------TASP 5489

Query: 999  ITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQ 1058
              E++   + +  +      G++ + +    +A  A + K+ + P+          +F  
Sbjct: 5490 DCEIIEDGKKHILILHNCQLGMTGEVSFQAANAKSAANLKVKELPL----------IFIT 5539

Query: 1059 PLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSP 1118
            PL +        A   C V   PK    W+K    I  D R+ +  +    ++ I+  + 
Sbjct: 5540 PLSDVKVFEKDEAKFECEVSREPK-TFRWLKGTQEITGDDRFELIKDGTKHSMVIKSAAF 5598

Query: 1119 YDGGTYCCKA 1128
             D   Y  +A
Sbjct: 5599 EDEAKYMFEA 5608



 Score = 36.2 bits (82), Expect = 0.18
 Identities = 39/146 (26%), Positives = 56/146 (38%), Gaps = 11/146 (7%)

Query: 301   LADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTEL 360
             L  PK  V W K  Q ++ + +  FE      IL IN C  +D   Y +TA +       
Sbjct: 14785 LGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLTARN------- 14837

Query: 361   FVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEG 420
              V E   ++T Q+ D        ++ + EVS D     W    E     P S Y + +  
Sbjct: 14838 IVGEVGDVITIQVHDIPGPPTGPIKFD-EVSSDFVTFSW-DPPENDGGVPISNYVVEMRQ 14895

Query: 421   KKHILIIEGATKADAAEYSV--MTTG 444
                   +E AT      Y    +TTG
Sbjct: 14896 TDSTTWVELATTVIRTTYKATRLTTG 14921



 Score = 35.8 bits (81), Expect = 0.24
 Identities = 25/91 (27%), Positives = 42/91 (46%), Gaps = 1/91 (1%)

Query: 559 TVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDS-STLVIDIAERD 617
           +V V+ G+    E  ISG P P+  W R  + I   +      S+ D  + L I    + 
Sbjct: 14  SVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKLTIPAVTKA 73

Query: 618 DSGVYHINLKNEAGEAHASIKVKVVDFPDPP 648
           +SG Y +   N +G+A ++ ++ V     PP
Sbjct: 74  NSGRYSLKATNGSGQATSTAELLVKAETAPP 104



 Score = 35.8 bits (81), Expect = 0.24
 Identities = 23/89 (25%), Positives = 34/89 (38%), Gaps = 2/89 (2%)

Query: 561   TVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSG--RIRTESYPDSSTLVIDIAERDD 618
             T   G  +R  + I+  P P   W +  + I  G    +   ES      L I+    DD
Sbjct: 25395 TAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDD 25454

Query: 619   SGVYHINLKNEAGEAHASIKVKVVDFPDP 647
                Y +  +N+ GE     K+ V   P P
Sbjct: 25455 DAEYTVVARNKYGEDSCKAKLTVTLHPPP 25483



 Score = 35.0 bits (79), Expect = 0.41
 Identities = 23/91 (25%), Positives = 37/91 (40%)

Query: 1054 PMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEI 1113
            P F Q L +     G    L   V G P P + + ++   I     +++     + +L I
Sbjct: 104  PNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLI 163

Query: 1114 RKPSPYDGGTYCCKAVNDLGTVEIECKLEVK 1144
             +  P D GTY   A N +G      +L V+
Sbjct: 164  AEAYPEDSGTYSVNATNSVGRATSTAELLVQ 194



 Score = 35.0 bits (79), Expect = 0.41
 Identities = 27/90 (30%), Positives = 39/90 (43%), Gaps = 4/90 (4%)

Query: 1054 PMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEI 1113
            P FT  L +  A+     TL C V  +   K  W K+   IV  P+Y + ++     L+I
Sbjct: 5358 PYFTVKLHDKTAVEKDEITLKCEVSKDVPVK--WFKDGEEIVPSPKYSIKADGLRRILKI 5415

Query: 1114 RKPSPYDGGTYCCKAVND--LGTVEIECKL 1141
            +K    D G Y C    D     V +E +L
Sbjct: 5416 KKADLKDKGEYVCDCGTDKTKANVTVEARL 5445



 Score = 33.9 bits (76), Expect = 0.91
 Identities = 27/119 (22%), Positives = 51/119 (42%), Gaps = 11/119 (9%)

Query: 418 VEGKKHILIIEGATKADAAEYSVM-------TTGGQSSAKLSVDLKPLKILTPLTDQTVN 470
           VE KK + +    T      + V+       T   +  A + + + P  +++ L + TV 
Sbjct: 850 VEVKKEVGVSITGTTVREERFEVLHGREAKVTETARVPAPVEIPVTPPTLVSGLKNVTVI 909

Query: 471 LGKEICLKCEISENIPGK---WTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDY 526
            G+ + L+C IS   P     W +    ++ S   ++  +  I +L+I  A  ED G +
Sbjct: 910 EGESVTLECHIS-GYPSPTVTWYREDYQIESSIDFQITFQSGIARLMIREAFAEDSGRF 967



 Score = 33.9 bits (76), Expect = 0.91
 Identities = 25/77 (32%), Positives = 40/77 (51%), Gaps = 8/77 (10%)

Query: 3    EPTKKEENEVPA-PAPPPEEPSKEKEAGTTPAKDEEEVSPPSALP---PGLGSRALERK- 57
            EP K E+ + PA P PPP +P +E E  T   K E ++  P+ +P   P +   A E K 
Sbjct: 4660 EPKKLEKVKKPAVPEPPPPKPVEEVEVPTV-TKRERKIPEPTKVPEIKPAIPLPAPEPKP 4718

Query: 58   --DSDWTLVETPPGEEQ 72
              +++   ++ PP E +
Sbjct: 4719 KPEAEVKTIKPPPVEPE 4735



 Score = 33.5 bits (75), Expect = 1.2
 Identities = 35/140 (25%), Positives = 63/140 (45%), Gaps = 11/140 (7%)

Query: 799 KTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIR 858
           + K TI  +         +KA N +G +     +  +LVK    PP     + L+   +R
Sbjct: 62  RAKLTIPAVTKANSGRYSLKATNGSGQATS---TAELLVKAETAPPNF--VQRLQSMTVR 116

Query: 859 RVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTI--IFIRKAERSHSGKY 916
           + G  V L +   G P P + + +DGAEI ++ ++ + S+   +  + I +A    SG Y
Sbjct: 117 Q-GSQVRLQVRVTGIPTPVVKFYRDGAEI-QSSLDFQISQEGDLYSLLIAEAYPEDSGTY 174

Query: 917 DLQV--KVDKFVETASIDIQ 934
            +     V +   TA + +Q
Sbjct: 175 SVNATNSVGRATSTAELLVQ 194



 Score = 33.5 bits (75), Expect = 1.2
 Identities = 43/147 (29%), Positives = 59/147 (40%), Gaps = 10/147 (6%)

Query: 304   PKLEVKWYKNGQE-IRPSTKY-IFEHKGCQRILFINNCQMTDDSEYYVTA----GDEKCS 357
             PK  VKWY+ G+E I    KY I E KG    L I +    D + Y V A    G    +
Sbjct: 24650 PKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQLIIASVTDDDATVYQVRATNQGGSVSGT 24709

Query: 358   TELFVREP-PIMVTKQLED---TTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSR 413
               L V  P  I + K LE      A  GE V ++   S     V  ++ G+++I      
Sbjct: 24710 ASLEVEVPAKIHLPKTLEGMGAVHALRGEVVSIKIPFSGKPDPVITWQKGQDLIDNNGHY 24769

Query: 414   YRIRVEGKKHILIIEGATKADAAEYSV 440
               I       ++   G  + DA  Y V
Sbjct: 24770 QVIVTRSFTSLVFPNGVERKDAGFYVV 24796



 Score = 33.1 bits (74), Expect = 1.6
 Identities = 21/96 (21%), Positives = 41/96 (42%), Gaps = 3/96 (3%)

Query: 854 QTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQ---INIRNSETDTIIFIRKAER 910
           Q+ +   G          G P PE++W +DG  I  +    + I  S+    + I    +
Sbjct: 13  QSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKLTIPAVTK 72

Query: 911 SHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVK 946
           ++SG+Y L+        T++ ++ +     PP  V+
Sbjct: 73  ANSGRYSLKATNGSGQATSTAELLVKAETAPPNFVQ 108



 Score = 33.1 bits (74), Expect = 1.6
 Identities = 19/61 (31%), Positives = 27/61 (44%), Gaps = 1/61 (1%)

Query: 1071 ATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVN 1130
            AT  C     P  K+ W K+ + + +  +YRM S++ V  L I      D   Y C  V 
Sbjct: 2146 ATFECET-SEPFVKVKWYKDGMEVHEGDKYRMHSDRKVHFLSILTIDTSDAEDYSCVLVE 2204

Query: 1131 D 1131
            D
Sbjct: 2205 D 2205



 Score = 33.1 bits (74), Expect = 1.6
 Identities = 55/256 (21%), Positives = 103/256 (40%), Gaps = 21/256 (8%)

Query: 304   PKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTA----GDEKCSTE 359
             P  ++KWY+ G+E+  S KY     G    L +   +  D+  Y   A    G+ + S++
Sbjct: 24255 PLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVGEVETSSK 24314

Query: 360   LFVREPPIMVT--KQLEDTTAYCGERVELE-CEVSEDDANVKWFKNGEEIIPGPKSRYRI 416
             L ++  P         E      G  + L    +      + WF +G++++   ++    
Sbjct: 24315 LLLQATPQFHPGYPLKEKYYGAVGSTLRLHVMYIGRPVPAMTWF-HGQKLLQNSENITIE 24373

Query: 417   RVEGKKHILIIEGATKADAAEYSVMTTG--GQSSAKLSVDL--KPLKILTPLTDQTVNLG 472
               E   H+++     K  A +Y V  +   G   A L V++  KP K   P+  + + L 
Sbjct: 24374 NTEHYTHLVMKNVQRKTHAGKYKVQLSNVFGTVDAILDVEIQDKPDKPTGPIVIEAL-LK 24432

Query: 473   KEICLKCEISENIPGKWTKNGL----PVQESDRLKVVHKG-RIHKLVIANALTEDEGDY- 526
                 +  +   +  G W  N +      +E    ++V     +    I N LTE+ G Y 
Sbjct: 24433 NSAVISWKPPADDGGSWITNYVVEKCEAKEGAEWQLVSSAISVTTCRIVN-LTENAGYYF 24491

Query: 527   -VFAPDAYNVTLPAKV 541
              V A + + ++ P +V
Sbjct: 24492 RVSAQNTFGISDPLEV 24507



 Score = 32.3 bits (72), Expect = 2.7
 Identities = 28/116 (24%), Positives = 51/116 (43%), Gaps = 8/116 (6%)

Query: 130  KAGKHLQLKETFERHSRVYTFEMQIIKAKDNFAGNYRCEVTYKDKFDSCSFDLEVHESTG 189
            KAG+ +   +     S  Y   ++I++ +    G Y C+ + +    SC+  L V     
Sbjct: 4564 KAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTV----- 4618

Query: 190  TTPNIDIRSAFKRSGEGQEDAGELDFSGLLKRREVKQQEEEPQVDVWELLKNAKPS 245
            T P  + +          E   E+    +L++R    +EEEP+V+  +L K  KP+
Sbjct: 4619 TVPGGEKKVRKLLPERKPEPKEEVVLKSVLRKR---PEEEEPKVEPKKLEKVKKPA 4671



 Score = 32.3 bits (72), Expect = 2.7
 Identities = 16/45 (35%), Positives = 22/45 (48%), Gaps = 3/45 (6%)

Query: 843   PPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEI 887
             PP+  +P + K  Y   VGE V   +     P P +TW K G +I
Sbjct: 25384 PPEFTLPLYNKTAY---VGENVRFGVTITVHPEPHVTWYKSGQKI 25425



 Score = 32.0 bits (71), Expect = 3.5
 Identities = 27/97 (27%), Positives = 39/97 (40%), Gaps = 5/97 (5%)

Query: 274  KKSAAFAKILDPAYQVDKGGRVRFVVELAD-PKLEVKWYKNGQEIRPSTKYIFEHKGCQR 332
            K++A   K      +V  G   +F  E+   P +  +W+K G+EI  S K          
Sbjct: 4525 KRAAPVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYIS 4584

Query: 333  ILFINNCQMTDDSEYYVTAGDE----KCSTELFVREP 365
             L I   Q+ D  EY   A +E     C+  L V  P
Sbjct: 4585 SLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVTVP 4621



 Score = 31.6 bits (70), Expect = 4.5
 Identities = 26/88 (29%), Positives = 33/88 (37%), Gaps = 4/88 (4%)

Query: 1059 PLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSP 1118
            PL +   I G  A L C V       + W  N   I  D R +         L I +   
Sbjct: 2404 PLKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVKGTKQRLVINRTHA 2463

Query: 1119 YDGGTYCCKAVNDLGTVEIECKLEVKVI 1146
             D G Y  K +  +G VE  C L V+ I
Sbjct: 2464 SDEGPY--KLI--VGRVETNCNLSVEKI 2487



 Score = 31.2 bits (69), Expect = 5.9
 Identities = 15/66 (22%), Positives = 30/66 (45%), Gaps = 1/66 (1%)

Query: 287   YQVDKGGRVRFVVE-LADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDS 345
             Y +  G  ++  +  +  P+  + W K+G+ ++ +T+   E      +L I      D  
Sbjct: 18016 YSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFG 18075

Query: 346   EYYVTA 351
             +Y VTA
Sbjct: 18076 KYTVTA 18081



 Score = 30.8 bits (68), Expect = 7.7
 Identities = 22/58 (37%), Positives = 28/58 (48%), Gaps = 6/58 (10%)

Query: 1    MPEPTKKEENE--VPAPAPPPEEPSKEKEAGTTPAKDEEEVSPPSALP---PGLGSRA 53
            +PEPTK  E +  +P PAP P +P  E E  T      E    P A P   P +G +A
Sbjct: 4696 IPEPTKVPEIKPAIPLPAPEP-KPKPEAEVKTIKPPPVEPEPTPIAAPVTVPVVGKKA 4752


>gi|110349713 titin isoform novex-1 [Homo sapiens]
          Length = 27051

 Score =  299 bits (766), Expect = 9e-81
 Identities = 218/756 (28%), Positives = 346/756 (45%), Gaps = 52/756 (6%)

Query: 297  FVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKC 356
            F  +L+  K  VKWY+NG+EI+   KY FE  G    L I +C++ D+ EY     D K 
Sbjct: 6470 FSCQLSREKANVKWYRNGREIKEGKKYKFEKDGSIHRLIIKDCRLDDECEYACGVEDRKS 6529

Query: 357  STELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRI 416
               LFV E P+ + +  +D     G  V    E+++D   V+W +N   ++ G K  +++
Sbjct: 6530 RARLFVEEIPVEIIRPPQDILEAPGADVVFLAELNKDKVEVQWLRNNMVVVQGDK--HQM 6587

Query: 417  RVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEIC 476
              EGK H L I      D  EY  +    ++ AKL +   P KI T   D  V++GK + 
Sbjct: 6588 MSEGKIHRLQICDIKPRDQGEYRFIAKDKEARAKLELAAAP-KIKTADQDLVVDVGKPLT 6646

Query: 477  LKC--EISENIPGKWTKNGLPV----------QESDRL---KVVHKGRIHKLVIANALTE 521
            +    +       +W K   P+          Q S R+   K   KGR +K+V+ N   +
Sbjct: 6647 MVVPYDAYPKAEAEWFKENEPLSTKTIDTTAEQTSFRILEAKKGDKGR-YKIVLQNKHGK 6705

Query: 522  DEGDYVFAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPK 581
             EG                + VID P  + +    + T T      L  E P++      
Sbjct: 6706 AEGFI-------------NLKVIDVPGPVRN---LEVTETFDGEVSLAWEEPLTDGGSKI 6749

Query: 582  AMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAG-----EAHAS 636
              +    + I   +  + T+        V  + +     ++ ++ +N  G     E    
Sbjct: 6750 IGYVVERRDIKRKTWVLATDRAESCEFTVTGLQKGGVEYLFRVSARNRVGTGEPVETDNP 6809

Query: 637  IKVKV-VDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLN 695
            ++ +   D P PP+  T+T+V      + WEPP YDGG+ I  Y IE + K S RW    
Sbjct: 6810 VEARSKYDVPGPPLNVTITDVNRFGVSLTWEPPEYDGGAEITNYVIELRDKTSIRWDTAM 6869

Query: 696  FDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFV----PLAVTSPPTLLTV 751
                ++ +     ++EG  Y  R+ A N IG+ KPS  + PFV    P+   SPP  LT 
Sbjct: 6870 TVRAEDLSATVTDVVEGQEYSFRVRAQNRIGVGKPSAAT-PFVKVADPIERPSPPVNLTS 6928

Query: 752  DSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDA 811
               T ++V ++W PP   G + + GY++E C EG ++WI  N  L+ +  + +TGL    
Sbjct: 6929 SDQTQSSVQLKWEPPLKDGGSPILGYIIERCEEGKDNWIRCNMKLVPELTYKVTGLEKGN 6988

Query: 812  KIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQ 871
            K   RV A N AG S+P     P+   +    P + +    K      V   + +++P  
Sbjct: 6989 KYLYRVSAENKAGVSDPSEILGPLTADDAFVEPTMDLSA-FKDGLEVIVPNPITILVPST 7047

Query: 872  GKPRPELTWKKDGAEIDK-NQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETAS 930
            G PRP  TW      ++  +++ ++       + I  +ERS  G Y L  K++  V+T S
Sbjct: 7048 GYPRPTATWCFGDKVLETGDRVKMKTLSAYAELVISPSERSDKGIYTL--KLENRVKTIS 7105

Query: 931  --IDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTV 988
              ID+ +I RP  P+ +K  D+  ++V LTW PP DDG + +TGY ++K +     W  V
Sbjct: 7106 GEIDVNVIARPSAPKELKFGDITKDSVHLTWEPPDDDGGSPLTGYVVEKREVSRKTWTKV 7165

Query: 989  IEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDA 1024
            ++       T+ +LV G EY F+V + N CG  E A
Sbjct: 7166 MDFVTDLEFTVPDLVQGKEYLFKVCARNKCGPGEPA 7201



 Score =  288 bits (737), Expect = 2e-77
 Identities = 165/503 (32%), Positives = 269/503 (53%), Gaps = 17/503 (3%)

Query: 536   TLPAKVHV---IDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIM 592
             TLP  V     I+PP+I LD  D    V + A   LRL + I G P P+  W + +  + 
Sbjct: 18719 TLPGSVVAQERIEPPEIELDA-DLRKVVVLRASATLRLFVTIKGRPEPEVKWEKAEGILT 18777

Query: 593   EGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPT 652
             +   R + E     + LVID   R DSG Y++ L+N +G   A + V+V+D P  PV  T
Sbjct: 18778 D---RAQIEVTSSFTMLVIDNVTRFDSGRYNLTLENNSGSKTAFVNVRVLDSPSAPVNLT 18834

Query: 653   VTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEG 712
             + EV  D   ++WEPP  DGG+ I  Y +E+++     +  +  + C +TTF  + + EG
Sbjct: 18835 IREVKKDSVTLSWEPPLIDGGAKITNYIVEKRETTRKAYATITNN-CTKTTFRIENLQEG 18893

Query: 713   VAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAA 772
              +Y  R+ A N  GI  P+  + P        PP  +T+  VT  T T++W  P+  G +
Sbjct: 18894 CSYYFRVLASNEYGIGLPAETTEPVKVSEPPLPPGRVTLVDVTRNTATIKWEKPESDGGS 18953

Query: 773   GLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYS 832
              + GYV+E   +G+E W    +  +   + TI+GL    +   RV AVN  G S+P+   
Sbjct: 18954 KITGYVVEMQTKGSEKWSTCTQ--VKTLEATISGLTAGEEYVFRVAAVNEKGRSDPRQLG 19011

Query: 833   QPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEI-DKNQ 891
              P++ ++I   P + +P H   T+  +  E + + +PF+G+P+  + W+KDG  + +  +
Sbjct: 19012 VPVIARDIEIKPSVELPFH---TFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTR 19068

Query: 892   INIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVW 951
             +N+ +S+T T + I++A +   G Y+L V       T  I I ++DRPGPP  ++I++V 
Sbjct: 19069 VNVSSSKTVTSLSIKEASKEDVGTYELCVSNSAGSITVPITIIVLDRPGPPGPIRIDEVS 19128

Query: 952   GENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFR 1011
              +++ ++W PP+ DG   I+ Y ++K +  S  W  V +   RTS  I  L  G+EY FR
Sbjct: 19129 CDSITISWNPPEYDGGCQISNYIVEKKETTSTTWHIVSQAVARTSIKIVRLTTGSEYQFR 19188

Query: 1012  VFSENMCGLSEDATMTKESAVIA 1034
             V +EN  G S   + ++ SAV+A
Sbjct: 19189 VCAENRYGKS---SYSESSAVVA 19208



 Score =  276 bits (707), Expect = 6e-74
 Identities = 176/570 (30%), Positives = 286/570 (50%), Gaps = 35/570 (6%)

Query: 463   PLTDQTVNLGKEICLKCEISENIPGKWTKNGLPVQ------ESDRLKVVHKGRIHKLVIA 516
             P+ D    +   I  KC++S    G+WT    P        E ++L   H+       I 
Sbjct: 16489 PIYDGGCEIQGYIVEKCDVSV---GEWTMCTPPTGINKTNIEVEKLLEKHEYNFRICAIN 16545

Query: 517   NALTEDEGDYVFAPDAYNVTLPAKVHV---IDPPKIILDGLDADNTVTVIAGNKLRLEIP 573
              A   +  D           +P  + V   ++ P I LD L+    + + AG  LRL +P
Sbjct: 16546 KAGVGEHAD-----------VPGPIIVEEKLEAPDIDLD-LELRKIINIRAGGSLRLFVP 16593

Query: 574   ISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEA 633
             I G P P+  W + D  I + +    T S+   ++LV+D   R DSG Y + L+N +G  
Sbjct: 16594 IKGRPTPEVKWGKVDGEIRDAAIIDVTSSF---TSLVLDNVNRYDSGKYTLTLENSSGTK 16650

Query: 634   HASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMR 693
              A + V+V+D P PPV   VTE+  D   + WEPP  DGGS I  Y +E+++     +  
Sbjct: 16651 SAFVTVRVLDTPSPPVNLKVTEITKDSVSITWEPPLLDGGSKIKNYIVEKREATRKSYAA 16710

Query: 694   LNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDS 753
             +  + C + +++  ++ EG +Y  R+ A N  GI  P+  + P     V  PP  +TVD 
Sbjct: 16711 VVTN-CHKNSWKIDQLQEGCSYYFRVTAENEYGIGLPAQTADPIKVAEVPQPPGKITVDD 16769

Query: 754   VTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKI 813
             VT  +V++ W  P+H G + +  Y++E   + +E W    +  +   +  IT L    + 
Sbjct: 16770 VTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKHSEKWSECAR--VKSLQAVITNLTQGEEY 16827

Query: 814   FVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGK 873
               RV AVN  G S+P+  + PI+ K+++  P +   +    +Y  +VG+ + + +P  G+
Sbjct: 16828 LFRVVAVNEKGRSDPRSLAVPIVAKDLVIEPDV---KPAFSSYSVQVGQDLKIEVPISGR 16884

Query: 874   PRPELTWKKDGAEIDK-NQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASID 932
             P+P +TW KDG  + +  +IN+ +S   T + I++  +   G+Y + V      +TASI+
Sbjct: 16885 PKPTITWTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQYGITVANVVGQKTASIE 16944

Query: 933   IQIIDRPGPPQ-IVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEH 991
             I  +D+P PP+  VK +DV  E++ L+W PP   G   IT Y +QK D  +  W  V   
Sbjct: 16945 IVTLDKPDPPKGPVKFDDVSAESITLSWNPPLYTGGCQITNYIVQKRDTTTTVWDVVSAT 17004

Query: 992   YHRTSATITELVIGNEYYFRVFSENMCGLS 1021
               RT+  +T+L  G EY FR+F+EN  G S
Sbjct: 17005 VARTTLKVTKLKTGTEYQFRIFAENRYGQS 17034



 Score =  272 bits (695), Expect = 2e-72
 Identities = 159/562 (28%), Positives = 280/562 (49%), Gaps = 19/562 (3%)

Query: 544   IDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESY 603
             ++ P++ LD  +    + V AG   R+ IP  G P P+  WSR +    E + +++ E  
Sbjct: 17647 LEAPELDLDS-ELRKGIVVRAGGSARIHIPFKGRPTPEITWSREEG---EFTDKVQIEKG 17702

Query: 604   PDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIM 663
              + + L ID  +R+D+G Y + L+N +G   A + VKV+D P PP    V EV  D   +
Sbjct: 17703 VNYTQLSIDNCDRNDAGKYILKLENSSGSKSAFVTVKVLDTPGPPQNLAVKEVRKDSAFL 17762

Query: 664   NWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVN 723
              WEPP  DGG+ +  Y I++++     +  ++   C +T+F+ + + EG  Y  R+ A N
Sbjct: 17763 VWEPPIIDGGAKVKNYVIDKRESTRKAYANVS-SKCSKTSFKVENLTEGAIYYFRVMAEN 17821

Query: 724   AIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCF 783
               G+  P             SPP  +T+  V+ T+ ++ W  P+H G + + GYV+E   
Sbjct: 17822 EFGVGVPVETVDAVKAAEPPSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVEMQP 17881

Query: 784   EGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEP 843
             +GTE W +  +  +      +TGL +  +   RVKA N  G S+P+    P++ K++   
Sbjct: 17882 KGTEKWSIVAESKV--CNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQ 17939

Query: 844   PKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDK-NQINIRNSETDTI 902
             P +++P +   TY  + GE + + IP  G+PRP ++W KDG  + +  ++N+  + T T+
Sbjct: 17940 PSLKLPFN---TYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTV 17996

Query: 903   IFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPP-QIVKIEDVWGENVALTWTP 961
             + I++  +   GKY +         T ++ + ++++PGPP   V+ ++V  + V ++W P
Sbjct: 17997 LHIKEGNKDDFGKYTVTATNSAGTATENLSVIVLEKPGPPVGPVRFDEVSADFVVISWEP 18056

Query: 962   PKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLS 1021
             P   G   I+ Y ++K D  +  W  V     RT+  IT+L  G EY FR+F+EN  G S
Sbjct: 18057 PAYTGGCQISNYIVEKRDTTTTTWHMVSATVARTTIKITKLKTGTEYQFRIFAENRYGKS 18116

Query: 1022  EDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNAT--LNCSVRG 1079
               A +  ++ ++      +K P      F  +    Q LV  +       T  +   +  
Sbjct: 18117 --APLDSKAVIVQYP---FKEPGPPGTPFVTSISKDQMLVQWHEPVNDGGTKIIGYHLEQ 18171

Query: 1080  NPKPKITWMKNKVAIVDDPRYR 1101
               K  I W+K     + D +++
Sbjct: 18172 KEKNSILWVKLNKTPIQDTKFK 18193



 Score =  258 bits (658), Expect = 3e-68
 Identities = 148/478 (30%), Positives = 252/478 (52%), Gaps = 12/478 (2%)

Query: 546   PPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPD 605
             PP+I LD  D    VT+ A   LRL +PI G P P+  W+R     ++ +    T SY  
Sbjct: 15485 PPEIELDA-DLRKVVTIRACCTLRLFVPIKGRPAPEVKWARDHGESLDKASIESTSSY-- 15541

Query: 606   SSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNW 665
              + L++    R DSG Y + ++N +G   A + V+V+D P PP    V EV      + W
Sbjct: 15542 -TLLIVGNVNRFDSGKYILTVENSSGSKSAFVNVRVLDTPGPPQDLKVKEVTKTSVTLTW 15600

Query: 666   EPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAI 725
             +PP  DGGS I  Y +E+++     +  +  + C +T+++  ++ EG +Y  R+ A N  
Sbjct: 15601 DPPLLDGGSKIKNYIVEKRESTRKAYSTVATN-CHKTSWKVDQLQEGCSYYFRVLAENEY 15659

Query: 726   GISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEG 785
             GI  P+  +          PP  +T+  VT  +V++ W  P+H G + + GY++E   +G
Sbjct: 15660 GIGLPAETAESVKASERPLPPGKITLMDVTRNSVSLSWEKPEHDGGSRILGYIVEMQTKG 15719

Query: 786   TEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPK 845
             ++ W  A    +  T+ TITGL    +   RV A N  G S+P+  S P++ K+++ PP 
Sbjct: 15720 SDKW--ATCATVKVTEATITGLIQGEEYSFRVSAQNEKGISDPRQLSVPVIAKDLVIPPA 15777

Query: 846   IRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDK-NQINIRNSETDTIIF 904
              ++   L  T+    GE + + +PF G+P P +TW KD   + +  ++N  ++E ++++ 
Sbjct: 15778 FKL---LFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAESTENNSLLT 15834

Query: 905   IRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQ-IVKIEDVWGENVALTWTPPK 963
             I+ A R   G Y +++         ++++ ++D+PGPP   VK+++V  +++ L+W PPK
Sbjct: 15835 IKDACREDVGHYVVKLTNSAGEAIETLNVIVLDKPGPPTGPVKMDEVTADSITLSWGPPK 15894

Query: 964   DDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLS 1021
              DG ++I  Y ++K D  +  W  V     RT+     L  G EY FR+ +EN  G S
Sbjct: 15895 YDGGSSINNYIVEKRDTSTTTWQIVSATVARTTIKACRLKTGCEYQFRIAAENRYGKS 15952



 Score =  255 bits (651), Expect = 2e-67
 Identities = 157/482 (32%), Positives = 251/482 (52%), Gaps = 13/482 (2%)

Query: 547   PKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDS 606
             P + LD    D  V V AG  +R+   +SG+PPP   W+  ++ + + +     E+   S
Sbjct: 10150 PDLQLDASVRDRIV-VHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEA---TIETTAIS 10205

Query: 607   STLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTE-VGDDWCIMNW 665
             S++VI   +R   GVY +  KNEAGE   +I V V+D P P   P +   + ++ C + W
Sbjct: 10206 SSMVIKNCQRSHQGVYSLLAKNEAGERKKTIIVDVLDVPGPVGTPFLAHNLTNESCKLTW 10265

Query: 666   EPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAI 725
               P  DGGSPI  Y IE+++     W  + + + ++     + +I+G AY  RI A N+I
Sbjct: 10266 FSPEDDGGSPITNYVIEKRESDRRAWTPVTYTVTRQNA-TVQGLIQGKAYFFRIAAENSI 10324

Query: 726   GISKPSMPSRPFV---PLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYC 782
             G+      S   V   P+ V   P  L V  VT  TVT+ W PP + G + +  YVLE  
Sbjct: 10325 GMGPFVETSEALVIREPITVPERPEDLEVKEVTKNTVTLTWNPPKYDGGSEIINYVLESR 10384

Query: 783   FEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIE 842
               GTE +     D +   K+T+ GL        RV AVN  G  +P + ++PI  K+ + 
Sbjct: 10385 LIGTEKFHKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGKPSFCTKPITCKDELA 10444

Query: 843   PPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEI-DKNQINIRNSETDT 901
             PP + +    K T   RVGEA  L   + GKP+P+++W KD A++ + ++ +I+ +    
Sbjct: 10445 PPTLHLDFRDKLTI--RVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATL 10502

Query: 902   IIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPP-QIVKIEDVWGENVALTWT 960
              +   KA+RS SGKY + V+           + ++DRPGPP   V  ++V  + + ++W 
Sbjct: 10503 ALEKIKAKRSDSGKYCVVVENSTGSRKGFCQVNVVDRPGPPVGPVSFDEVTKDYMVISWK 10562

Query: 961   PPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGL 1020
             PP DDG + IT Y I+K +     W  V     +T+  +++L+ G +Y FR+ +EN+ G+
Sbjct: 10563 PPLDDGGSKITNYIIEKKEVGKDVWMPVTSASAKTTCKVSKLLEGKDYIFRIHAENLYGI 10622

Query: 1021  SE 1022
             S+
Sbjct: 10623 SD 10624



 Score =  255 bits (651), Expect = 2e-67
 Identities = 143/470 (30%), Positives = 242/470 (51%), Gaps = 16/470 (3%)

Query: 559   TVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSS----TLVIDIA 614
             T+ V AG    + +P  G P P  +WS+ D  +       RT +Y D++    +L I+ A
Sbjct: 19823 TLIVKAGASFTMTVPFRGRPVPNVLWSKPDTDL-------RTRAYVDTTDSRTSLTIENA 19875

Query: 615   ERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGS 674
              R+DSG Y + ++N    A  ++ VKV+D P PP   TV +V  +  +++W+ P  DGG+
Sbjct: 19876 NRNDSGKYTLTIQNVLSAASLTLVVKVLDTPGPPTNITVQDVTKESAVLSWDVPENDGGA 19935

Query: 675   PILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPS 734
             P+  Y IE+++     W+ +  + C   +++   + EG  Y  R+   N  G+  P+   
Sbjct: 19936 PVKNYHIEKREASKKAWVSVT-NNCNRLSYKVTNLQEGAIYYFRVSGENEFGVGIPAETK 19994

Query: 735   RPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANK 794
                      SPP  L V S++  +V++ W  P+H G + +  YV+E   +G ++W+    
Sbjct: 19995 EGVKITEKPSPPEKLGVTSISKDSVSLTWLKPEHDGGSRIVHYVVEALEKGQKNWVKC-- 20052

Query: 795   DLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQ 854
              +   T   ++GL  +++ F RV A N AG S+P+    P+L+KE +EPP+I +      
Sbjct: 20053 AVAKSTHHVVSGLRENSEYFFRVFAENQAGLSDPRELLLPVLIKEQLEPPEIDMKNFPSH 20112

Query: 855   TYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKN-QINIRNSETDTIIFIRKAERSHS 913
             T   R G  + + IP  GKP P++T  +DG  +    + N   +  +  I ++++  + +
Sbjct: 20113 TVYVRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADA 20172

Query: 914   GKYDLQVKVDKFVETASIDIQIIDRPGPPQ-IVKIEDVWGENVALTWTPPKDDGNAAITG 972
             G+Y++          A I+I ++DRPGPP   V I D+  E+V L W PPK DG + +T 
Sbjct: 20173 GRYEITAANSSGTTKAFINIVVLDRPGPPTGPVVISDITEESVTLKWEPPKYDGGSQVTN 20232

Query: 973   YTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSE 1022
             Y + K +  +  W  V     RT   + +L  G EY FR+ +EN  G+S+
Sbjct: 20233 YILLKRETSTAVWTEVSATVARTMMKVMKLTTGEEYQFRIKAENRFGISD 20282



 Score =  252 bits (644), Expect = 1e-66
 Identities = 152/470 (32%), Positives = 240/470 (51%), Gaps = 10/470 (2%)

Query: 555   DADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIA 614
             D   TVT+ AG  LRL + +SG PPP   WS+    +   +    TESY   S L++D  
Sbjct: 23079 DLKKTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAIIDTTESY---SLLIVDKV 23135

Query: 615   ERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGS 674
              R D+G Y I  +N++G+  A++ VKV D P P  +  V EV  D   + WE P  DGG+
Sbjct: 23136 NRYDAGKYTIEAENQSGKKSATVLVKVYDTPGPCPSVKVKEVSRDSVTITWEIPTIDGGA 23195

Query: 675   PILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPS 734
             P+  Y +E K++ + R  +     C +T +    ++EG  Y  R+   N  GI +P   S
Sbjct: 23196 PVNNYIVE-KREAAMRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYGIGEPCETS 23254

Query: 735   RPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDW--IVA 792
                +   V   P  L V  VT +TVT+ W  P + G + L GYVLE C  GTE W  +V 
Sbjct: 23255 DAVLVSEVPLVPAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGTERWMKVVT 23314

Query: 793   NKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHL 852
              K  +   + T+T L    +   R++A N  G SEP+     + V+++   P I +    
Sbjct: 23315 LKPTV--LEHTVTSLNEGEQYLFRIRAQNEKGVSEPRETVTAVTVQDLRVLPTIDLSTMP 23372

Query: 853   KQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEI-DKNQINIRNSETDTIIFIRKAERS 911
             ++T     G  V LVIP  G+P P  +W   G+++ +  ++ +        + IR+    
Sbjct: 23373 QKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAKLTIRETTIR 23432

Query: 912   HSGKYDLQVKVDKFVETASIDIQIIDRPGPPQ-IVKIEDVWGENVALTWTPPKDDGNAAI 970
              +G+Y L++K      + +I + I+D+PGPP   +KI+++   ++ ++W PP+ DG A +
Sbjct: 23433 DTGEYTLELKNVTGTTSETIKVIILDKPGPPTGPIKIDEIDATSITISWEPPELDGGAPL 23492

Query: 971   TGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGL 1020
             +GY +++ D     W  V E   R++   T L  GNEY FRV + N  G+
Sbjct: 23493 SGYVVEQRDAHRPGWLPVSESVTRSTFKFTRLTEGNEYVFRVAATNRFGI 23542



 Score =  249 bits (636), Expect = 1e-65
 Identities = 151/508 (29%), Positives = 245/508 (48%), Gaps = 22/508 (4%)

Query: 533  YNVTLPAKVHVIDPPKIILDGLDADNT--------------VTVIAGNKLRLEIPISGEP 578
            Y V+   K  V DP +I L  L AD+               + VI  N + + +P +G P
Sbjct: 6992 YRVSAENKAGVSDPSEI-LGPLTADDAFVEPTMDLSAFKDGLEVIVPNPITILVPSTGYP 7050

Query: 579  PPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIK 638
             P A W  GDK ++E   R++ ++    + LVI  +ER D G+Y + L+N        I 
Sbjct: 7051 RPTATWCFGDK-VLETGDRVKMKTLSAYAELVISPSERSDKGIYTLKLENRVKTISGEID 7109

Query: 639  VKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDL 698
            V V+  P  P      ++  D   + WEPP  DGGSP+ GY +E+++     W ++  D 
Sbjct: 7110 VNVIARPSAPKELKFGDITKDSVHLTWEPPDDDGGSPLTGYVVEKREVSRKTWTKV-MDF 7168

Query: 699  CKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPF---VPLAVTSPPTLLTVDSVT 755
              +  F    +++G  Y  ++ A N  G  +P+    P     P  V  PP  +     T
Sbjct: 7169 VTDLEFTVPDLVQGKEYLFKVCARNKCGPGEPAYVDEPVNMSTPATVPDPPENVKWRDRT 7228

Query: 756  DTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFV 815
              ++ + W PP + G + + GY++E C  G++ W+   +  + +TK  +TGL        
Sbjct: 7229 ANSIFLTWDPPKNDGGSRIKGYIVERCPRGSDKWVACGEP-VAETKMEVTGLEEGKWYAY 7287

Query: 816  RVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPR 875
            RVKA+N  GAS+P   ++ I   +  E P+I +   L      + G  + L     GKP 
Sbjct: 7288 RVKALNRQGASKPSRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPE 7347

Query: 876  PELTWKKDGAEIDKN-QINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQ 934
            P++TW K    + ++ +I I N    + + I  ++RS +G Y ++        TA +++ 
Sbjct: 7348 PKITWTKADMILKQDKRITIENVPKKSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVN 7407

Query: 935  IIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHR 994
            ++D+PGPP    I DV  E+  LTW PP+DDG + IT Y +++    S  W  +      
Sbjct: 7408 VLDKPGPPAAFDITDVTNESCLLTWNPPRDDGGSKITNYVVERRATDSEVWHKLSSTVKD 7467

Query: 995  TSATITELVIGNEYYFRVFSENMCGLSE 1022
            T+   T+L+   EY FRV +ENM G+ E
Sbjct: 7468 TNFKATKLIPNKEYIFRVAAENMYGVGE 7495



 Score =  247 bits (631), Expect = 4e-65
 Identities = 170/584 (29%), Positives = 278/584 (47%), Gaps = 33/584 (5%)

Query: 461   LTPLTDQTVNL--GKEICLKCEISENIP--GKWTKNGLPVQESDRLKVVHKGRIHKLVIA 516
             L+ +  +T+++  G+ + L   I+   P    W   G  ++ES+R+ V    ++ KL I 
Sbjct: 23368 LSTMPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAKLTIR 23427

Query: 517   NALTEDEGDYVFAPDAYNVTLPA----KVHVIDPP-----KIILDGLDADNTVTVIAGNK 567
                  D G+Y    +  NVT       KV ++D P      I +D +DA +        +
Sbjct: 23428 ETTIRDTGEYTL--ELKNVTGTTSETIKVIILDKPGPPTGPIKIDEIDATSITISWEPPE 23485

Query: 568   LRLEIPISG-----EPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVY 622
             L    P+SG         +  W    +++   + +    +  +     +    R   G Y
Sbjct: 23486 LDGGAPLSGYVVEQRDAHRPGWLPVSESVTRSTFKFTRLTEGNEYVFRVAATNRFGIGSY 23545

Query: 623   HINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIE 682
                L++E  E  +SI++     P PP    + +V  D   + W PP  DGGS + GY +E
Sbjct: 23546 ---LQSEVIECRSSIRI-----PGPPETLQIFDVSRDGMTLTWYPPEDDGGSQVTGYIVE 23597

Query: 683   RKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAV 742
             RK+ ++ RW+R+N      T +    + EG+ YE R+ A+NA G  KPS PS+P V +  
Sbjct: 23598 RKEVRADRWVRVNKVPVTMTRYRSTGLTEGLEYEHRVTAINARGSGKPSRPSKPIVAMDP 23657

Query: 743   TSPPTLLTVDSVTDTT---VTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDK 799
              +PP       VTDTT   V++ W  P+  G + + GY++E       +W   N      
Sbjct: 23658 IAPPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTKCNTTPTKI 23717

Query: 800   TKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRR 859
              ++T+T LP  A+   RV A NA G  EP      + V E++E P   +    ++    R
Sbjct: 23718 REYTLTHLPQGAEYRFRVLACNAGGPGEPAEVPGTVKVTEMLEYPDYELDERYQEGIFVR 23777

Query: 860   VGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQ 919
              G  + L IP +GKP P   W K+G +I K  + I  SET T + I++A+R  SG YDL 
Sbjct: 23778 QGGVIRLTIPIKGKPFPICKWTKEGQDISKRAM-IATSETHTELVIKEADRGDSGTYDLV 23836

Query: 920   VKVDKFVETASIDIQIIDRPGPPQ-IVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKA 978
             ++     +   I +++I  P  P+  ++ +D+   +V ++W PP DDG A I GY +++ 
Sbjct: 23837 LENKCGKKAVYIKVRVIGSPNSPEGPLEYDDIQVRSVRVSWRPPADDGGADILGYILERR 23896

Query: 979   DKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSE 1022
             +     W+T+      TS  +  L    EY+FRV +EN  G+S+
Sbjct: 23897 EVPKAAWYTIDSRVRGTSLVVKGLKENVEYHFRVSAENQFGISK 23940



 Score =  245 bits (626), Expect = 2e-64
 Identities = 153/493 (31%), Positives = 238/493 (48%), Gaps = 17/493 (3%)

Query: 543   VIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRG--DKAIMEGSGRIRT 600
             +++PP+I LD       V V AG  +RL   + G P PK  W +   D  + +G    + 
Sbjct: 12228 ILEPPEIDLDA-SMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVVRKG----QV 12282

Query: 601   ESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDW 660
             +     + LVI  + RDDSG Y + L N AGE    + V+V+D P P     V++V    
Sbjct: 12283 DLVDTMAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFVNVRVLDTPGPVSDLKVSDVTKTS 12342

Query: 661   CIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIF 720
             C ++W PP  DGGS +  Y +E+++     W  +  ++ K+T+F    ++ G  Y  R+ 
Sbjct: 12343 CHVSWAPPENDGGSQVTHYIVEKREADRKTWSTVTPEV-KKTSFHVTNLVPGNEYYFRVT 12401

Query: 721   AVNAIGISKPSMPSRPFV---PLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGY 777
             AVN  G   P+   +P +   PL+   PP  L V  +T  + T+ W PP   G A +DGY
Sbjct: 12402 AVNEYGPGVPTDVPKPVLASDPLSEPDPPRKLEVTEMTKNSATLAWLPPLRDGGAKIDGY 12461

Query: 778   VLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILV 837
             +  Y  E           ++      +TGL    K   RV A NA G S P+        
Sbjct: 12462 ITSYREEEQPADRWTEYSVVKDLSLVVTGLKEGKKYKFRVAARNAVGVSLPREAEGVYEA 12521

Query: 838   KEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAE-IDKNQINIRN 896
             KE + PPKI +P  +      + G+ + +     GKP P   WKK   E +  + + +  
Sbjct: 12522 KEQLLPPKILMPEQI----TIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHK 12577

Query: 897   SETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQ-IVKIEDVWGENV 955
             +++ +I+ I+   R  SG Y L  +     +T  I + ++D PGPPQ    I D+  +  
Sbjct: 12578 ADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPGPPQPPFDISDIDADAC 12637

Query: 956   ALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSE 1015
             +L+W  P +DG + IT Y ++K D    +W T +    +TS  + +L+ G EY FRV +E
Sbjct: 12638 SLSWHIPLEDGGSNITNYIVEKCDVSRGDWVTALASVTKTSCRVGKLIPGQEYIFRVRAE 12697

Query: 1016  NMCGLSEDATMTK 1028
             N  G+SE  T  K
Sbjct: 12698 NRFGISEPLTSPK 12710



 Score =  243 bits (621), Expect = 6e-64
 Identities = 152/515 (29%), Positives = 259/515 (50%), Gaps = 25/515 (4%)

Query: 543   VIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTES 602
             ++ PP+  LD  D   T+ + AG  +RL +P+ G PPPK  WS+ +  + +  G +  +S
Sbjct: 13315 ILIPPEGELDA-DLRKTLILRAGVTMRLYVPVKGRPPPKITWSKPNVNLRDRIG-LDIKS 13372

Query: 603   YPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCI 662
                 + L  +   + D+G Y + L+N  G+   +I VKV+D P PPV  TV E+  D   
Sbjct: 13373 TDFDTFLRCENVNKYDAGKYILTLENSCGKKEYTIVVKVLDTPGPPVNVTVKEISKDSAY 13432

Query: 663   MNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAV 722
             + WEPP  DGGSPI+ Y ++++  +   W  +  + C +T+F    + EG +Y  R+FA 
Sbjct: 13433 VTWEPPIIDGGSPIINYVVQKRDAERKSWSTVTTE-CSKTSFRVANLEEGKSYFFRVFAE 13491

Query: 723   NAIGISKPSMPSRPFVPLAVTSPPTL-LTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEY 781
             N  GI  P   +R  V  + T  P + L V SV+ ++ ++ W+ P   G + + GYV+++
Sbjct: 13492 NEYGIGDPG-ETRDAVKASQTPGPVVDLKVRSVSKSSCSIGWKKPHSDGGSRIIGYVVDF 13550

Query: 782   CFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEII 841
               E  + W    K L    +++   L    +   RV A N  G   P   +  ++ ++ +
Sbjct: 13551 LTEENK-WQRVMKSL--SLQYSAKDLTEGKEYTFRVSAENENGEGTPSEIT--VVARDDV 13605

Query: 842   EPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKK-DGAEIDKNQINIRNSETD 900
               P + +       Y+ +      L IP +GKP P ++WKK +       ++++ +S  +
Sbjct: 13606 VAPDLDLKGLPDLCYLAKENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVESSAVN 13665

Query: 901   TIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPG-PPQIVKIEDVWGENVALTW 959
             T + +   ++S +GKY + +K     +  +I I+++ +PG P   +K ++V  E + L W
Sbjct: 13666 TTLIVYDCQKSDAGKYTITLKNVAGTKEGTISIKVVGKPGIPTGPIKFDEVTAEAMTLKW 13725

Query: 960   TPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCG 1019
              PPKDDG + IT Y ++K D  + +W T      +T+  +T L  G EY FRV +EN  G
Sbjct: 13726 APPKDDGGSEITNYILEKRDSVNNKWVTCASAVQKTTFRVTRLHEGMEYTFRVSAENKYG 13785

Query: 1020  LSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAP 1054
             + E     K   ++AR            FD  +AP
Sbjct: 13786 VGEG---LKSEPIVAR----------HPFDVPDAP 13807



 Score =  243 bits (620), Expect = 8e-64
 Identities = 202/709 (28%), Positives = 322/709 (45%), Gaps = 69/709 (9%)

Query: 357   STELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKW----FKNGEEIIP---- 408
             S  L +REP I V ++ ED        +E++ EV+++   + W    +  G EII     
Sbjct: 10333 SEALVIREP-ITVPERPED--------LEVK-EVTKNTVTLTWNPPKYDGGSEIINYVLE 10382

Query: 409   ----GPKSRYRIRVEGK-KHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTP 463
                 G +  +++  +        ++G  + D  EY V         K S   KP+     
Sbjct: 10383 SRLIGTEKFHKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGKPSFCTKPITCKDE 10442

Query: 464   LTDQTVNLGKEICLKCEISE------NIPGK------WTKNGLPVQESDRLKVVHKGRIH 511
             L   T++L     L   + E         GK      W K+   V E DR  +       
Sbjct: 10443 LAPPTLHLDFRDKLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATL 10502

Query: 512   KLVIANALTEDEGDYVFAPDAYNVTLPAK----VHVIDPPKIILDGLDADNTVTVIAGNK 567
              L    A   D G Y    +  N T   K    V+V+D P   +  +  D          
Sbjct: 10503 ALEKIKAKRSDSGKYCVVVE--NSTGSRKGFCQVNVVDRPGPPVGPVSFDEVT------- 10553

Query: 568   LRLEIPISGEPPPKAMWSRGDKAIMEGSGRIR------TESYPDSSTLVIDIAERDDSGV 621
              +  + IS +PP     S+    I+E     +      T +   ++  V  + E  D  +
Sbjct: 10554 -KDYMVISWKPPLDDGGSKITNYIIEKKEVGKDVWMPVTSASAKTTCKVSKLLEGKDY-I 10611

Query: 622   YHINLKNEAG--EAHASIKVKVVD---FPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPI 676
             + I+ +N  G  +   S  +K  D    PD P  P VTEV  D  ++ W  P +DGG PI
Sbjct: 10612 FRIHAENLYGISDPLVSDSMKAKDRFRVPDAPDQPIVTEVTKDSALVTWNKP-HDGGKPI 10670

Query: 677   LGYFIERKKKQSSRWMRLNFD-LCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSR 735
               Y +E+++  S RW R+  D +   T F    ++EG  YE R+ A N IGI  PS PS+
Sbjct: 10671 TNYILEKRETMSKRWARVTKDPIHPYTKFRVPDLLEGCQYEFRVSAENEIGIGDPSPPSK 10730

Query: 736   PFV---PLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVA 792
             P     P+A  SPP        T  +V + W+PP H G + + GY++EY   G E+W  A
Sbjct: 10731 PVFAKDPIAKPSPPVNPEAIDTTCNSVDLTWQPPRHDGGSKILGYIVEYQKVGDEEWRRA 10790

Query: 793   NK--DLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPR 850
             N   +   +TK+ +TGL        RV AVNAAG S+P +  +P+LVK+ +EPP++ +  
Sbjct: 10791 NHTPESCPETKYKVTGLRDGQTYKFRVLAVNAAGESDPAHVPEPVLVKDRLEPPELILDA 10850

Query: 851   HLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAER 910
             ++ +    +VG+ + L    +G P P++TWKK+  +    +  I  +   + + IR A  
Sbjct: 10851 NMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAP-TKARIDVTPVGSKLEIRNAAH 10909

Query: 911   SHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAI 970
                G Y L V+     +T S+ + ++D+PGPP+ +++ ++  ++  LTW  P DDG + I
Sbjct: 10910 EDGGIYSLTVENPAGSKTVSVKVLVLDKPGPPRDLEVSEIRKDSCYLTWKEPLDDGGSVI 10969

Query: 971   TGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCG 1019
             T Y +++ D  S +W  +     + S     L  GN+Y FRV +EN  G
Sbjct: 10970 TNYVVERRDVASAQWSPLSATSKKKSHFAKHLNEGNQYLFRVAAENQYG 11018



 Score =  243 bits (620), Expect = 8e-64
 Identities = 166/560 (29%), Positives = 272/560 (48%), Gaps = 26/560 (4%)

Query: 489   WTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAKVH--VIDP 546
             W K+G+ ++E  R +++       L + + +  D G YV        T    V+  V+D 
Sbjct: 19451 WAKDGIEIEERARTEIISTDNHTLLTVKDCIRRDTGQYVLTLKNVAGTRSVAVNCKVLDK 19510

Query: 547   P-----KIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTE 601
             P      + ++GL A+         +      I      K   S     I EG  ++   
Sbjct: 19511 PGPPAGPLEINGLTAEKCSLSWGRPQEDGGADIDYYIVEKRETSHLAWTICEGELQM--- 19567

Query: 602   SYPDSSTLVIDIAERDDSGVYHINLKNE--AGEAHASIKVKVVD---FPDPPVAPTVTEV 656
                 +S  V  + + ++  ++ +   N+   GE   S+ +K +D    P PP +  +T V
Sbjct: 19568 ----TSCKVTKLLKGNEY-IFRVTGVNKYGVGEPLESVAIKALDPFTVPSPPTSLEITSV 19622

Query: 657   GDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYE 716
               +   + W  P  DGGS I GY IER++K S RW+R+N     +   +   + EG  YE
Sbjct: 19623 TKESMTLCWSRPESDGGSEISGYIIERREKNSLRWVRVNKKPVYDLRVKSTGLREGCEYE 19682

Query: 717   VRIFAVNAIGISKPSMPS---RPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAG 773
              R++A NA G+S PS  S   R   P+ + SPP+   +     TT+T+ W  P   G A 
Sbjct: 19683 YRVYAENAAGLSLPSETSPLIRAEDPVFLPSPPSKPKIVDSGKTTITIAWVKPLFDGGAP 19742

Query: 774   LDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQ 833
             + GY +EY      DW  + + L   T++TI+GL T A+   RVK+VN  GAS+P   S 
Sbjct: 19743 ITGYTVEYKKSDDTDWKTSIQSLRG-TEYTISGLTTGAEYVFRVKSVNKVGASDPSDSSD 19801

Query: 834   PILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQIN 893
             P + KE  E P   I   +++T I + G +  + +PF+G+P P + W K   ++ + +  
Sbjct: 19802 PQIAKEREEEPLFDIDSEMRKTLIVKAGASFTMTVPFRGRPVPNVLWSKPDTDL-RTRAY 19860

Query: 894   IRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGE 953
             +  +++ T + I  A R+ SGKY L ++      + ++ ++++D PGPP  + ++DV  E
Sbjct: 19861 VDTTDSRTSLTIENANRNDSGKYTLTIQNVLSAASLTLVVKVLDTPGPPTNITVQDVTKE 19920

Query: 954   NVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVF 1013
             +  L+W  P++DG A +  Y I+K +     W +V  + +R S  +T L  G  YYFRV 
Sbjct: 19921 SAVLSWDVPENDGGAPVKNYHIEKREASKKAWVSVTNNCNRLSYKVTNLQEGAIYYFRVS 19980

Query: 1014  SENMCGLSEDATMTKESAVI 1033
              EN  G+   A  TKE   I
Sbjct: 19981 GENEFGVGIPAE-TKEGVKI 19999



 Score =  241 bits (614), Expect = 4e-63
 Identities = 135/381 (35%), Positives = 198/381 (51%), Gaps = 3/381 (0%)

Query: 645   PDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTF 704
             P PP  P VT V  D   ++W  P  DGGSPILGY +ERK++    W  ++  L     F
Sbjct: 14887 PGPPGTPQVTAVTKDSMTISWHEPLSDGGSPILGYHVERKERNGILWQTVSKALVPGNIF 14946

Query: 705   EPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWR 764
             +   + +G+AYE R+ A N  G SKPS PS P + L    PP      ++T  TVT++W 
Sbjct: 14947 KSSGLTDGIAYEFRVIAENMAGKSKPSKPSEPMLALDPIDPPGKPVPLNITRHTVTLKWA 15006

Query: 765   PPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAG 824
              P++ G   +  Y++E        W+ AN   I + +FT++GL  DA    RV A NAAG
Sbjct: 15007 KPEYTGGFKITSYIVEKRDLPNGRWLKANFSNILENEFTVSGLTEDAAYEFRVIAKNAAG 15066

Query: 825   A-SEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKD 883
             A S P   S  I  ++ +E PKI++    K T I + GEA  L     G+P P + W KD
Sbjct: 15067 AISPPSEPSDAITCRDDVEAPKIKVDVKFKDTVILKAGEAFRLEADVSGRPPPTMEWSKD 15126

Query: 884   GAEIDKN-QINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPP 942
             G E++   ++ I+ ++  T +  + + R  SG Y L             +++++DRPGPP
Sbjct: 15127 GKELEGTAKLEIKIADFSTNLVNKDSTRRDSGAYTLTATNPGGFAKHIFNVKVLDRPGPP 15186

Query: 943   Q-IVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITE 1001
             +  + + +V  E   L+W PP DDG A I  Y +QK +   + W  V      T   +T+
Sbjct: 15187 EGPLAVTEVTSEKCVLSWFPPLDDGGAKIDHYIVQKRETSRLAWTNVASEVQVTKLKVTK 15246

Query: 1002  LVIGNEYYFRVFSENMCGLSE 1022
             L+ GNEY FRV + N  G+ E
Sbjct: 15247 LLKGNEYIFRVMAVNKYGVGE 15267



 Score =  240 bits (613), Expect = 5e-63
 Identities = 159/591 (26%), Positives = 282/591 (47%), Gaps = 40/591 (6%)

Query: 454   DLKPLKILTPLTDQTVNLGKEICLKCEISENIPGK--WTKNGLPVQESDRLKVVHKGRIH 511
             D+KP       +  +V +G+++ ++  IS        WTK+GLP++++ R+ V     + 
Sbjct: 16859 DVKPA-----FSSYSVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLT 16913

Query: 512   KLVIANALTEDEGDYVFAPDAYNVTLPAKVHVI-----DPPK--IILDGLDADNTVTVIA 564
              L I     +D G Y            A + ++     DPPK  +  D + A++      
Sbjct: 16914 TLSIKETHKDDGGQYGITVANVVGQKTASIEIVTLDKPDPPKGPVKFDDVSAES------ 16967

Query: 565   GNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRT-----ESYPDSSTLVIDIAERDDS 619
                    I +S  PP      +    I++      T      +    +TL +   +    
Sbjct: 16968 -------ITLSWNPPLYTGGCQITNYIVQKRDTTTTVWDVVSATVARTTLKVTKLKTGTE 17020

Query: 620   GVYHINLKNEAGEAHASIKVKVV-----DFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGS 674
               + I  +N  G++ A     +V       P PP  P  T +  D  ++ W  P  +GGS
Sbjct: 17021 YQFRIFAENRYGQSFALESDPIVAQYPYKEPGPPGTPFATAISKDSMVIQWHEPVNNGGS 17080

Query: 675   PILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPS 734
             P++GY +ERK++ S  W ++N  +  +T F+ + + EG+ YE R++A N +G+ K S  S
Sbjct: 17081 PVIGYHLERKERNSILWTKVNKTIIHDTQFKAQNLEEGIEYEFRVYAENIVGVGKASKNS 17140

Query: 735   RPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANK 794
               +V      PP       V    +T++W  P + G + + GY++E        W+ A+ 
Sbjct: 17141 ECYVARDPCDPPGTPEPIMVKRNEITLQWTKPVYDGGSMITGYIVEKRDLPDGRWMKASF 17200

Query: 795   DLIDKTKFTITGLPTDAKIFVRVKAVNAAGA-SEPKYYSQPILVKEIIEPPKIRIPRHLK 853
               + +T+FT++GL  D +   RV A NAAGA S+P   + PI  K+ +E P+I +    +
Sbjct: 17201 TNVIETQFTVSGLTEDQRYEFRVIAKNAAGAISKPSDSTGPITAKDEVELPRISMDPKFR 17260

Query: 854   QTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKN-QINIRNSETDTIIFIRKAERSH 912
              T +   GE   L     GKP P + W +   EI+++ +  I+N++   ++ ++ A R  
Sbjct: 17261 DTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRID 17320

Query: 913   SGKYDLQVKVDKFVETASIDIQIIDRPGPPQ-IVKIEDVWGENVALTWTPPKDDGNAAIT 971
              G+Y L+       ++  ++++++DRPGPP+  V++  V  E  +LTW+PP  DG + I+
Sbjct: 17321 GGQYILRASNVAGSKSFPVNVKVLDRPGPPEGPVQVTGVTSEKCSLTWSPPLQDGGSDIS 17380

Query: 972   GYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSE 1022
              Y ++K +   + W  V       S  +T+L+ GNEY FR+ + N  G+ E
Sbjct: 17381 HYVVEKRETSRLAWTVVASEVVTNSLKVTKLLEGNEYVFRIMAVNKYGVGE 17431



 Score =  239 bits (611), Expect = 8e-63
 Identities = 148/495 (29%), Positives = 245/495 (49%), Gaps = 10/495 (2%)

Query: 531   DAYNVTLPAK-VHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDK 589
             D+  VT   K V  +  P++ +D  +   T  V AG  +RL I   G P P A+WS+ D 
Sbjct: 21966 DSCEVTGTIKAVDRLTAPELDIDA-NFKQTHVVRAGASIRLFIAYQGRPTPTAVWSKPDS 22024

Query: 590   AIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPV 649
              +   +    T+S+   STL ++   R+D+G Y + ++N +G    +  VKV+D P PP 
Sbjct: 22025 NLSLRADIHTTDSF---STLTVENCNRNDAGKYTLTVENNSGSKSITFTVKVLDTPGPPG 22081

Query: 650   APTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKM 709
               T  +V      + W+ P  DGG+ I  Y +E+++     W  ++ + C    F+   +
Sbjct: 22082 PITFKDVTRGSATLMWDAPLLDGGARIHHYVVEKREASRRSWQVIS-EKCTRQIFKVNDL 22140

Query: 710   IEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHI 769
              EGV Y  R+ AVN  G+ +P     P V     +PP  L V   + ++  + W  PDH 
Sbjct: 22141 AEGVPYYFRVSAVNEYGVGEPYEMPEPIVATEQPAPPRRLDVVDTSKSSAVLAWLKPDHD 22200

Query: 770   GAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPK 829
             G + + GY+LE   +G++ W+ A      +  FT+  L    +   RVKA N AG SEP+
Sbjct: 22201 GGSRITGYLLEMRQKGSDFWVEAGH--TKQLTFTVERLVEKTEYEFRVKAKNDAGYSEPR 22258

Query: 830   YYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEI-D 888
                  +++KE    P   +     Q    + G    + +P  G+P P++TWK +   + +
Sbjct: 22259 EAFSSVIIKEPQIEPTADLTGITNQLITCKAGSPFTIDVPISGRPAPKVTWKLEEMRLKE 22318

Query: 889   KNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGP-PQIVKI 947
              ++++I  ++  T + ++ + R  SG+Y L ++    V+T S+ + +I RPGP    +++
Sbjct: 22319 TDRVSITTTKDRTTLTVKDSMRGDSGRYFLTLENTAGVKTFSVTVVVIGRPGPVTGPIEV 22378

Query: 948   EDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNE 1007
               V  E+  L+W  PKD G   IT Y ++K +  +  W  V     RT   +T L    E
Sbjct: 22379 SSVSAESCVLSWGEPKDGGGTEITNYIVEKRESGTTAWQLVNSSVKRTQIKVTHLTKYME 22438

Query: 1008  YYFRVFSENMCGLSE 1022
             Y FRV SEN  G+S+
Sbjct: 22439 YSFRVSSENRFGVSK 22453



 Score =  238 bits (608), Expect = 2e-62
 Identities = 155/491 (31%), Positives = 238/491 (48%), Gaps = 15/491 (3%)

Query: 544   IDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESY 603
             ++PP++ILD   A     +  G+ LRL   I G P PK  W + D+   +   + R +  
Sbjct: 10841 LEPPELILDANMAREQ-HIKVGDTLRLSAIIKGVPFPKVTWKKEDR---DAPTKARIDVT 10896

Query: 604   PDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIM 663
             P  S L I  A  +D G+Y + ++N AG    S+KV V+D P PP    V+E+  D C +
Sbjct: 10897 PVGSKLEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDKPGPPRDLEVSEIRKDSCYL 10956

Query: 664   NWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVN 723
              W+ P  DGGS I  Y +ER+   S++W  L+    K++ F  K + EG  Y  R+ A N
Sbjct: 10957 TWKEPLDDGGSVITNYVVERRDVASAQWSPLSATSKKKSHF-AKHLNEGNQYLFRVAAEN 11015

Query: 724   AIG---ISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLE 780
               G     +   P +   PL    PP  L    V  T V++ W  PD  G + + GY++E
Sbjct: 11016 QYGRGPFVETPKPIKALDPLHPPGPPKDLHHVDVDKTEVSLVWNKPDRDGGSPITGYLVE 11075

Query: 781   YCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEI 840
             Y  EGT+DWI      +   +  +TGL        RVKA N  G   P   + PI  +E 
Sbjct: 11076 YQEEGTQDWI--KFKTVTNLECVVTGLQQGKTYRFRVKAENIVGLGLPD-TTIPIECQEK 11132

Query: 841   IEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQ-INIRNSET 899
             + PP + +   L +  + + G  V      +G P P   W  DG+EI  ++   +     
Sbjct: 11133 LVPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNF 11192

Query: 900   DTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQ-IVKIEDVWGENVALT 958
              +++ I+   R  +G+Y + V      +T ++ + ++D PGPP   + I DV  E++ ++
Sbjct: 11193 SSVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTVLDVPGPPTGPINILDVTPEHMTIS 11252

Query: 959   WTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMC 1018
             W PPKDDG + +  Y ++K D +   W  V     +T   I  L  G EY FRV +EN  
Sbjct: 11253 WQPPKDDGGSPVINYIVEKQDTRKDTWGVVSSGSSKTKLKIPHLQKGCEYVFRVRAENKI 11312

Query: 1019  GLSE--DATMT 1027
             G+    D+T T
Sbjct: 11313 GVGPPLDSTPT 11323



 Score =  238 bits (607), Expect = 2e-62
 Identities = 169/593 (28%), Positives = 282/593 (47%), Gaps = 27/593 (4%)

Query: 266  LKRMRREEKKSAAFA-------KILDPAYQVDKGGR--VRFVVELADPKLEVKWYKNGQE 316
            L   R E  KSAA         +I++P   ++   +  V F  ++    + +KW KNG+E
Sbjct: 6341 LTNHRGENVKSAANLIVEEEDLRIVEPLKDIETMEKKSVTFWCKVNRLNVTLKWTKNGEE 6400

Query: 317  IRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTELFVREPPIMVTKQLEDT 376
            +    +  +     + +L I +C   D+ EY VTAG +K   EL + E P    + LED 
Sbjct: 6401 VPFDNRVSYRVDKYKHMLTIKDCGFPDEGEYIVTAGQDKSVAELLIIEAPTEFVEHLEDQ 6460

Query: 377  TAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAA 436
            T    +     C++S + ANVKW++NG EI  G K  Y+   +G  H LII+     D  
Sbjct: 6461 TVTEFDDAVFSCQLSREKANVKWYRNGREIKEGKK--YKFEKDGSIHRLIIKDCRLDDEC 6518

Query: 437  EYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCEIS-ENIPGKWTKNGLP 495
            EY+      +S A+L V+  P++I+ P  D     G ++    E++ + +  +W +N + 
Sbjct: 6519 EYACGVEDRKSRARLFVEEIPVEIIRPPQDILEAPGADVVFLAELNKDKVEVQWLRNNMV 6578

Query: 496  VQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKIILDGLD 555
            V + D+ +++ +G+IH+L I +    D+G+Y F   A +    AK+ +   PKI      
Sbjct: 6579 VVQGDKHQMMSEGKIHRLQICDIKPRDQGEYRFI--AKDKEARAKLELAAAPKI----KT 6632

Query: 556  ADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAE 615
            AD  + V  G  L + +P    P  +A W + ++ +   +     ++  + ++  I  A+
Sbjct: 6633 ADQDLVVDVGKPLTMVVPYDAYPKAEAEWFKENEPLSTKT----IDTTAEQTSFRILEAK 6688

Query: 616  RDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSP 675
            + D G Y I L+N+ G+A   I +KV+D P P     VTE  D    + WE P  DGGS 
Sbjct: 6689 KGDKGRYKIVLQNKHGKAEGFINLKVIDVPGPVRNLEVTETFDGEVSLAWEEPLTDGGSK 6748

Query: 676  ILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIE-GVAYEVRIFAVNAIGISKPSMPS 734
            I+GY +ER+  +   W+ L  D  +   F    + + GV Y  R+ A N +G  +P    
Sbjct: 6749 IIGYVVERRDIKRKTWV-LATDRAESCEFTVTGLQKGGVEYLFRVSARNRVGTGEPVETD 6807

Query: 735  RPFVPLA---VTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIV 791
             P    +   V  PP  +T+  V    V++ W PP++ G A +  YV+E   + +  W  
Sbjct: 6808 NPVEARSKYDVPGPPLNVTITDVNRFGVSLTWEPPEYDGGAEITNYVIELRDKTSIRWDT 6867

Query: 792  ANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPP 844
            A     +    T+T +    +   RV+A N  G  +P   +  + V + IE P
Sbjct: 6868 AMTVRAEDLSATVTDVVEGQEYSFRVRAQNRIGVGKPSAATPFVKVADPIERP 6920



 Score =  238 bits (607), Expect = 2e-62
 Identities = 172/634 (27%), Positives = 302/634 (47%), Gaps = 44/634 (6%)

Query: 411   KSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVN 470
             K++Y+ R   +  + I   +  +D    +++         LSV +K L         TV 
Sbjct: 12887 KAQYQFRAIARTAVNISPPSEPSDPV--TILAENVPPRIDLSVAMKSLL--------TVK 12936

Query: 471   LGKEICLKCEI-SENIPG-KWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVF 528
              G  +CL   +  + +P   W K+G  ++ ++ +K+  +  +  L + +   +D GDY  
Sbjct: 12937 AGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTI 12996

Query: 529   APDAYNVTLPA--KVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSR 586
               +  + +  A  K+ V+D P     G  A   +  +  ++  L    S EPP +   S 
Sbjct: 12997 TAENSSGSKSATIKLKVLDKP-----GPPASVKINKMYSDRAML----SWEPPLEDGGSE 13047

Query: 587   GDKAIMEGSGRIRTESYPDSSTLVI---DIAERDDSGVYHINL--KNEAGEA-----HAS 636
                 I++     R      S+T+ I    + +  +   Y   +  +N+ G         +
Sbjct: 13048 ITNYIVDKRETSRPNWAQVSATVPITSCSVEKLIEGHEYQFRICAENKYGVGDPVFTEPA 13107

Query: 637   IKVKVVDFP---DPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMR 693
             I     D P   DPPV   +T+   D   ++W+PPA DGGSPI GY +E+++ Q+  W +
Sbjct: 13108 IAKNPYDPPGRCDPPVISNITK---DHMTVSWKPPADDGGSPITGYLLEKRETQAVNWTK 13164

Query: 694   LNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFV---PLAVTSPPTLLT 750
             +N     E T +   + EG  YE R+ A+N  G  KPS  S+      P     PP    
Sbjct: 13165 VNRKPIIERTLKATGLQEGTEYEFRVTAINKAGPGKPSDASKAAYARDPQYPPGPPAFPK 13224

Query: 751   VDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVAN-KDLIDKTKFTITGLPT 809
             V   T ++V++ W  P + G + + GY++E     +++W+  N    + KT+F +TGL  
Sbjct: 13225 VYDTTRSSVSLSWGKPAYDGGSPIIGYLVEVKRADSDNWVRCNLPQNLQKTRFEVTGLME 13284

Query: 810   DAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIP 869
             D +   RV AVN  G S+P         K+I+ PP+  +   L++T I R G  + L +P
Sbjct: 13285 DTQYQFRVYAVNKIGYSDPSDVPDKHYPKDILIPPEGELDADLRKTLILRAGVTMRLYVP 13344

Query: 870   FQGKPRPELTWKKDGAEI-DKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVET 928
              +G+P P++TW K    + D+  ++I++++ DT +      +  +GKY L ++     + 
Sbjct: 13345 VKGRPPPKITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKYILTLENSCGKKE 13404

Query: 929   ASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTV 988
              +I ++++D PGPP  V ++++  ++  +TW PP  DG + I  Y +QK D +   W TV
Sbjct: 13405 YTIVVKVLDTPGPPVNVTVKEISKDSAYVTWEPPIIDGGSPIINYVVQKRDAERKSWSTV 13464

Query: 989   IEHYHRTSATITELVIGNEYYFRVFSENMCGLSE 1022
                  +TS  +  L  G  Y+FRVF+EN  G+ +
Sbjct: 13465 TTECSKTSFRVANLEEGKSYFFRVFAENEYGIGD 13498



 Score =  238 bits (606), Expect = 3e-62
 Identities = 182/680 (26%), Positives = 309/680 (45%), Gaps = 62/680 (9%)

Query: 389   EVSEDDANVKWFK----NGEEII-------PGPKSRYRIRVEGKKHILIIEGATKADAAE 437
             +VS+  A++ W K     G  ++       P    ++ I  E K    ++ G +     +
Sbjct: 17851 DVSQTSASLMWEKPEHDGGSRVLGYVVEMQPKGTEKWSIVAESKVCNAVVTGLSSGQEYQ 17910

Query: 438   YSVMTTG--GQSSAKL--------SVDLKPLKILTPLTDQTVNLGKEICLKCEI----SE 483
             + V      G+S  ++         + ++P  +  P    ++  G+++ ++  +      
Sbjct: 17911 FRVKAYNEKGKSDPRVLGVPVIAKDLTIQP-SLKLPFNTYSIQAGEDLKIEIPVIGRPRP 17969

Query: 484   NIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAP--DAYNVTLPAKV 541
             NI   W K+G P++++ R+ V        L I     +D G Y       A   T    V
Sbjct: 17970 NI--SWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKYTVTATNSAGTATENLSV 18027

Query: 542   HVIDPP-----KIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSG 596
              V++ P      +  D + AD  V             IS EPP      +    I+E   
Sbjct: 18028 IVLEKPGPPVGPVRFDEVSADFVV-------------ISWEPPAYTGGCQISNYIVEKRD 18074

Query: 597   RIRTESYPDSSTLV---IDIAERDDSGVYHINL--KNEAGE-AHASIKVKVVDFP----D 646
                T  +  S+T+    I I +      Y   +  +N  G+ A    K  +V +P     
Sbjct: 18075 TTTTTWHMVSATVARTTIKITKLKTGTEYQFRIFAENRYGKSAPLDSKAVIVQYPFKEPG 18134

Query: 647   PPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEP 706
             PP  P VT +  D  ++ W  P  DGG+ I+GY +E+K+K S  W++LN    ++T F+ 
Sbjct: 18135 PPGTPFVTSISKDQMLVQWHEPVNDGGTKIIGYHLEQKEKNSILWVKLNKTPIQDTKFKT 18194

Query: 707   KKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPP 766
               + EG+ YE ++ A N +GI KPS  S  FV      PP       +T   VT++W+ P
Sbjct: 18195 TGLDEGLEYEFKVSAENIVGIGKPSKVSECFVARDPCDPPGRPEAIVITRNNVTLKWKKP 18254

Query: 767   DHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAG-A 825
              + G + + GY++E        W+ A+   + +T+FT++GL  D +   RV A NAAG  
Sbjct: 18255 AYDGGSKITGYIVEKKDLPDGRWMKASFTNVLETEFTVSGLVEDQRYEFRVIARNAAGNF 18314

Query: 826   SEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGA 885
             SEP   S  I  ++ I+ P   +    K   +   GE   L    +GKP P++ W KDG 
Sbjct: 18315 SEPSDSSGAITARDEIDAPNASLDPKYKDVIVVHAGETFVLEADIRGKPIPDVVWSKDGK 18374

Query: 886   EIDKN--QINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQ 943
             E+++   ++ I+++   T + ++   R+  G+Y L++      ++  I ++++DRPGPP+
Sbjct: 18375 ELEETAARMEIKSTIQKTTLVVKDCIRTDGGQYILKLSNVGGTKSIPITVKVLDRPGPPE 18434

Query: 944   -IVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITEL 1002
               +K+  V  E   L W PP  DG A I+ Y I+K +   + W  V       +  +T+L
Sbjct: 18435 GPLKVTGVTAEKCYLAWNPPLQDGGANISHYIIEKRETSRLSWTQVSTEVQALNYKVTKL 18494

Query: 1003  VIGNEYYFRVFSENMCGLSE 1022
             + GNEY FRV + N  G+ E
Sbjct: 18495 LPGNEYIFRVMAVNKYGIGE 18514



 Score =  234 bits (598), Expect = 3e-61
 Identities = 141/476 (29%), Positives = 240/476 (50%), Gaps = 11/476 (2%)

Query: 554   LDAD--NTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVI 611
             LDA+   T+ V AG  +R+ +PI G P P+  W++ +  +   +    TES+   + L+I
Sbjct: 14406 LDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKNRANIENTESF---TLLII 14462

Query: 612   DIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYD 671
                 R D+G + + ++N AG+    + V+V+D P P +    T++  D   ++W+ P  D
Sbjct: 14463 PECNRYDTGKFVMTIENPAGKKSGFVNVRVLDTPGPVLNLRPTDITKDSVTLHWDLPLID 14522

Query: 672   GGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPS 731
             GGS I  Y +E+++     +       C + T++   + EG  Y  R+ A N  GI +P+
Sbjct: 14523 GGSRITNYIVEKREATRKSYSTATTK-CHKCTYKVTGLSEGCEYFFRVMAENEYGIGEPT 14581

Query: 732   MPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIV 791
               + P       SPP  L +  +T +TV++ W  P H G + + GYV+E   +G++ W  
Sbjct: 14582 ETTEPVKASEAPSPPDSLNIMDITKSTVSLAWPKPKHDGGSKITGYVIEAQRKGSDQW-- 14639

Query: 792   ANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRH 851
              +   +   +  +  L    +   +V AVN+AG S P+  S+P++VKE    P++ +   
Sbjct: 14640 THITTVKGLECVVRNLTEGEEYTFQVMAVNSAGRSAPR-ESRPVIVKEQTMLPELDLRGI 14698

Query: 852   LKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQ-INIRNSETDTIIFIRKAER 910
              ++  I + G+ + + IP  G+P+P +TWKK    + + Q +N   + T TI+ I +  R
Sbjct: 14699 YQKLVIAKAGDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVR 14758

Query: 911   SHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQ-IVKIEDVWGENVALTWTPPKDDGNAA 969
             S SG Y L  +         I IQ+ D PGPP   +K ++V  + V  +W PP++DG   
Sbjct: 14759 SDSGPYPLTARNIVGEVGDVITIQVHDIPGPPTGPIKFDEVSSDFVTFSWDPPENDGGVP 14818

Query: 970   ITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDAT 1025
             I+ Y ++     S  W  +     RT+   T L  G EY FRV ++N  G+    T
Sbjct: 14819 ISNYVVEMRQTDSTTWVELATTVIRTTYKATRLTTGLEYQFRVKAQNRYGVGPGIT 14874



 Score =  233 bits (595), Expect = 6e-61
 Identities = 168/591 (28%), Positives = 280/591 (47%), Gaps = 38/591 (6%)

Query: 453   VDLKPLKILTPLTDQTVNLGKEICLKCEISENIPGKWTKNGLPVQESDRLKVVHKGRIHK 512
             +DLK   +LT     T+ L  E  ++ +    +     K+   +  S R+K+  +    K
Sbjct: 11831 LDLKLSGVLTVKAGDTIRL--EAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSK 11888

Query: 513   LVIANALTEDEGDYVFAPD--AYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRL 570
               +  A   D G YV      A +    A V+V+D P     G   +  +  ++ ++   
Sbjct: 11889 FSLTKAKRSDGGKYVVTATNTAGSFVAYATVNVLDKP-----GPVRNLKIVDVSSDRCT- 11942

Query: 571   EIPISGEPPPKAMWSRGDKAIMEG--SGRIRTESYPDS----STLVIDIAERDDSGVYHI 624
                +  +PP           I+E   + R+   +Y  +     T V  + E ++  ++ +
Sbjct: 11943 ---VCWDPPEDDGGCEIQNYILEKCETKRMVWSTYSATVLTPGTTVTRLIEGNEY-IFRV 11998

Query: 625   NLKNEAG-----EAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGY 679
               +N+ G     E+   I     D P  P  P VT+V  +   + W PP YDGG  I GY
Sbjct: 11999 RAENKIGTGPPTESKPVIAKTKYDKPGRPDPPEVTKVSKEEMTVVWNPPEYDGGKSITGY 12058

Query: 680   FIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFV- 738
             F+E+K+K S+RW+ +N     E   + + ++    Y+ R+ A N IGI +PS+PSRP V 
Sbjct: 12059 FLEKKEKHSTRWVPVNKSAIPERRMKVQNLLPDHEYQFRVKAENEIGIGEPSLPSRPVVA 12118

Query: 739   --PLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYC-----FEGTEDWIV 791
               P+    PPT   V   T  ++T+ W  P + G A + GYV+E           E W  
Sbjct: 12119 KDPIEPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAPIIGYVVEMRPKIADASPDEGWKR 12178

Query: 792   ANKDL-IDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPR 850
              N    + + +FT+T L  + +   RV A N  G   P    + I  KEI+EPP+I +  
Sbjct: 12179 CNAAAQLVRKEFTVTSLDENQEYEFRVCAQNQVGIGRPAELKEAIKPKEILEPPEIDLDA 12238

Query: 851   HLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAE--IDKNQINIRNSETDTIIFIRKA 908
              +++  I R G  + L    +G+P P++TW+K G +  + K Q+++   +T   + I  +
Sbjct: 12239 SMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVVRKGQVDL--VDTMAFLVIPNS 12296

Query: 909   ERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNA 968
              R  SGKY L +      +   ++++++D PGP   +K+ DV   +  ++W PP++DG +
Sbjct: 12297 TRDDSGKYSLTLVNPAGEKAVFVNVRVLDTPGPVSDLKVSDVTKTSCHVSWAPPENDGGS 12356

Query: 969   AITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCG 1019
              +T Y ++K +     W TV     +TS  +T LV GNEYYFRV + N  G
Sbjct: 12357 QVTHYIVEKREADRKTWSTVTPEVKKTSFHVTNLVPGNEYYFRVTAVNEYG 12407



 Score =  233 bits (594), Expect = 8e-61
 Identities = 159/513 (30%), Positives = 252/513 (49%), Gaps = 34/513 (6%)

Query: 545  DPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWS---RGDKAIMEGSGRI--- 598
            + P++ +D + A + +   AG+++R+   I G P PK+ W    +  KA+ +G   I   
Sbjct: 9434 EEPEVFID-IGAQDCLVCKAGSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPED 9492

Query: 599  -RTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVG 657
             + E+  +SS ++I   +R  +G Y I  KN+AG+  A+ +VKV+D P PP    V+++ 
Sbjct: 9493 AQLETAENSSVIIIPECKRSHTGKYSITAKNKAGQKTANCRVKVMDVPGPPKDLKVSDIT 9552

Query: 658  DDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEV 717
               C ++W+ P  DGG  I GY IE++      W ++N D C  TTF    ++    Y  
Sbjct: 9553 RGSCRLSWKMPDDDGGDRIKGYVIEKRTIDGKAWTKVNPD-CGSTTFVVPDLLSEQQYFF 9611

Query: 718  RIFAVNAIGISKPSMPSRPFV---PLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGL 774
            R+ A N  GI  P    +      P+    PP  L +  +T  TV + W+PP + G + +
Sbjct: 9612 RVRAENRFGIGPPVETIQRTTARDPIYPPDPPIKLKIGLITKNTVHLSWKPPKNDGGSPV 9671

Query: 775  DGYVLEYCF----EGT--EDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEP 828
              Y++E C      GT  E W   NK  +++ +FT+  L    +   RVKAVNAAG S+P
Sbjct: 9672 THYIVE-CLAWDPTGTKKEAWRQCNKRDVEELQFTVEDLVEGGEYEFRVKAVNAAGVSKP 9730

Query: 829  KYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTW------KK 882
                 P   +    PP I     LK+      G  VN+V   +G P P LTW      K 
Sbjct: 9731 SATVGPCDCQRPDMPPSI----DLKEFMEVEEGTNVNIVAKIKGVPFPTLTWFKAPPKKP 9786

Query: 883  DGAE---IDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRP 939
            D  E    D +   +   +T T++ I ++ RS +G Y +    +    +  + + ++ RP
Sbjct: 9787 DNKEPVLYDTHVNKLVVDDTCTLV-IPQSRRSDTGLYTITAVNNLGTASKEMRLNVLGRP 9845

Query: 940  GPP-QIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSAT 998
            GPP   +K E V  + + L+W PPKDDG + IT Y I+K +     W  V       + T
Sbjct: 9846 GPPVGPIKFESVSADQMTLSWFPPKDDGGSKITNYVIEKREANRKTWVHVSSEPKECTYT 9905

Query: 999  ITELVIGNEYYFRVFSENMCGLSEDATMTKESA 1031
            I +L+ G+EY FR+ ++N  G+ E      E+A
Sbjct: 9906 IPKLLEGHEYVFRIMAQNKYGIGEPLDSEPETA 9938



 Score =  230 bits (587), Expect = 5e-60
 Identities = 156/568 (27%), Positives = 267/568 (47%), Gaps = 24/568 (4%)

Query: 490   TKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKI 549
             +++G+P++ + R           + +  ++T D G Y       + T  A ++++     
Sbjct: 20139 SRDGVPLKATMRFNTEITAENLTINLKESVTADAGRYEITAANSSGTTKAFINIV----- 20193

Query: 550   ILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIM---EGSGRIRTESYPDS 606
             +LD      T  V+  +     + +  EPP     S+    I+   E S  + TE     
Sbjct: 20194 VLDR-PGPPTGPVVISDITEESVTLKWEPPKYDGGSQVTNYILLKRETSTAVWTEVSATV 20252

Query: 607   STLVIDIAERDDSGVYHINLKNE--------AGEAHASIKVKVVDFPDPPVAPTVTEVGD 658
             +  ++ + +      Y   +K E           A  ++K+     P PP  P VT V  
Sbjct: 20253 ARTMMKVMKLTTGEEYQFRIKAENRFGISDHIDSACVTVKLPYTT-PGPPSTPWVTNVTR 20311

Query: 659   DWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVR 718
             +   + W  P  +GGS ++GY +E K + S  W + N  + + T F+   +  G+ YE R
Sbjct: 20312 ESITVGWHEPVSNGGSAVVGYHLEMKDRNSILWQKANKLVIRTTHFKVTTISAGLIYEFR 20371

Query: 719   IFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYV 778
             ++A NA G+ KPS PS P + +    PP  + +  ++  +V++ W+ P   G + + GY+
Sbjct: 20372 VYAENAAGVGKPSHPSEPVLAIDACEPPRNVRITDISKNSVSLSWQQPAFDGGSKITGYI 20431

Query: 779   LEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGA-SEPKYYSQPILV 837
             +E        W  A+   + +T+F I+GL  +++   RV A NA G+ S P     PI  
Sbjct: 20432 VERRDLPDGRWTKASFTNVTETQFIISGLTQNSQYEFRVFARNAVGSISNPSEVVGPITC 20491

Query: 838   KEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNS 897
              +    P I +P    +    R G +V L     GKP P + W KD  E+  N +    +
Sbjct: 20492 IDSYGGPVIDLPLEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVEN 20551

Query: 898   ETD-TIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPP-QIVKIEDVWGENV 955
              TD   I I+ A+R +SG Y+L+++      +A+I +QI+D+PGPP   ++ + V  E +
Sbjct: 20552 TTDLASILIKDADRLNSGCYELKLRNAMGSASATIRVQILDKPGPPGGPIEFKTVTAEKI 20611

Query: 956   ALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSE 1015
              L W PP DDG A IT Y ++K +   + W  V EH      T T+++ GNEY FRV + 
Sbjct: 20612 TLLWRPPADDGGAKITHYIVEKRETSRVVWSMVSEHLEECIITTTKIIKGNEYIFRVRAV 20671

Query: 1016  NMCGLSEDATMTKESAVIARDGKIYKNP 1043
             N  G+ E     +  +V+A++  +   P
Sbjct: 20672 NKYGIGEP---LESDSVVAKNAFVTPGP 20696



 Score =  230 bits (586), Expect = 7e-60
 Identities = 161/526 (30%), Positives = 248/526 (47%), Gaps = 48/526 (9%)

Query: 545  DPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYP 604
            + P+I LD +     +TV AG K+ L   ++G+P PK  W++ D  I++   RI  E+ P
Sbjct: 7314 EAPEIFLD-VKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADM-ILKQDKRITIENVP 7371

Query: 605  DSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMN 664
              ST+ I  ++R D+G Y I   N  G A A ++V V+D P PP A  +T+V ++ C++ 
Sbjct: 7372 KKSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNVLDKPGPPAAFDITDVTNESCLLT 7431

Query: 665  WEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNA 724
            W PP  DGGS I  Y +ER+   S  W +L+    K+T F+  K+I    Y  R+ A N 
Sbjct: 7432 WNPPRDDGGSKITNYVVERRATDSEVWHKLS-STVKDTNFKATKLIPNKEYIFRVAAENM 7490

Query: 725  IGISKP--SMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYC 782
             G+ +P  + P           PPT L    +T   VT+ W  PD  G + + GY +E  
Sbjct: 7491 YGVGEPVQASPITAKYQFDPPGPPTRLEPSDITKDAVTLTWCEPDDDGGSPITGYWVERL 7550

Query: 783  FEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIE 842
               T+ W+  NK  +  T + + GL    K   RV A N AG  +P   ++PIL+K+ I+
Sbjct: 7551 DPDTDKWVRCNKMPVKDTTYRVKGLTNKKKYRFRVLAENLAGPGKPSKSTEPILIKDPID 7610

Query: 843  PPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKK----DGAEIDKNQINIRNSE 898
            PP       +K                  GK    L W K     GA+I+   I +  + 
Sbjct: 7611 PPWPPGKPTVKDV----------------GKTSVRLNWTKPEHDGGAKIESYVIEMLKTG 7654

Query: 899  TDTIIFIRKAE-----------RSHSGKYDLQVK-VDKFVETASID-------IQIIDRP 939
            TD   ++R AE                +Y  +V+ V+K  E+   +        + +  P
Sbjct: 7655 TDE--WVRVAEGVPTTQHLLPGLMEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPP 7712

Query: 940  GPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATI 999
             PP+ +++ ++      L WT P+ DG + IT Y ++K D +   W TV      T  T+
Sbjct: 7713 SPPRWLEVINITKNTADLKWTVPEKDGGSPITNYIVEKRDVRRKGWQTVDTTVKDTKCTV 7772

Query: 1000 TELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVY 1045
            T L  G+ Y FRV +EN  G S+   +  E +V+A+D      P Y
Sbjct: 7773 TPLTEGSLYVFRVAAENAIGQSDYTEI--EDSVLAKDTFTTPGPPY 7816



 Score =  230 bits (586), Expect = 7e-60
 Identities = 154/553 (27%), Positives = 257/553 (46%), Gaps = 32/553 (5%)

Query: 489   WTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVF--APDAYNVTLPAKVHVIDP 546
             W K+G  ++E+ R+ V     +  L I  A  ED G Y    +  A ++T+P  + V+D 
Sbjct: 19056 WRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSNSAGSITVPITIIVLDR 19115

Query: 547   P----KIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTES 602
             P     I +D +  D+             I IS  PP      +    I+E      T  
Sbjct: 19116 PGPPGPIRIDEVSCDS-------------ITISWNPPEYDGGCQISNYIVEKKETTSTTW 19162

Query: 603   YPDSSTLV---IDIAERDDSGVYHINL-------KNEAGEAHASIKVKVVDFPDPPVAPT 652
             +  S  +    I I        Y   +       K+   E+ A +       P PP  P 
Sbjct: 19163 HIVSQAVARTSIKIVRLTTGSEYQFRVCAENRYGKSSYSESSAVVAEYPFSPPGPPGTPK 19222

Query: 653   VTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEG 712
             V        ++ W+ P  DGGS ++GY +E K++ S  W + N  L  +T  +   + EG
Sbjct: 19223 VVHATKSTMLVTWQVPVNDGGSRVIGYHLEYKERSSILWSKANKILIADTQMKVSGLDEG 19282

Query: 713   VAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAA 772
             + YE R++A N  GI K S    P        PP    V ++T  +V+++W  P + G A
Sbjct: 19283 LMYEYRVYAENIAGIGKCSKSCEPVPARDPCDPPGQPEVTNITRKSVSLKWSKPHYDGGA 19342

Query: 773   GLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAA-GASEPKYY 831
              + GY++E        W+  N   I +T F +T L  D +   RV A NAA   SEP   
Sbjct: 19343 KITGYIVERRELPDGRWLKCNYTNIQETYFEVTELTEDQRYEFRVFARNAADSVSEPSES 19402

Query: 832   SQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKN- 890
             + PI+VK+ +EPP++ +    +   + + GE + +     G+P P ++W KDG EI++  
Sbjct: 19403 TGPIIVKDDVEPPRVMMDVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERA 19462

Query: 891   QINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQ-IVKIED 949
             +  I +++  T++ ++   R  +G+Y L +K      + +++ +++D+PGPP   ++I  
Sbjct: 19463 RTEIISTDNHTLLTVKDCIRRDTGQYVLTLKNVAGTRSVAVNCKVLDKPGPPAGPLEING 19522

Query: 950   VWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYY 1009
             +  E  +L+W  P++DG A I  Y ++K +   + W         TS  +T+L+ GNEY 
Sbjct: 19523 LTAEKCSLSWGRPQEDGGADIDYYIVEKRETSHLAWTICEGELQMTSCKVTKLLKGNEYI 19582

Query: 1010  FRVFSENMCGLSE 1022
             FRV   N  G+ E
Sbjct: 19583 FRVTGVNKYGVGE 19595



 Score =  229 bits (583), Expect = 1e-59
 Identities = 169/620 (27%), Positives = 271/620 (43%), Gaps = 26/620 (4%)

Query: 419   EGKKHILIIEGATKADAAEYSVMTTGGQSSAKL-SVDLKPLKILTPLTDQTVNLGKEICL 477
             EGK++   +    +      S +T   +       +DLK L  L  L  +  N   +I +
Sbjct: 13575 EGKEYTFRVSAENENGEGTPSEITVVARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPI 13634

Query: 478   KCEISENIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTL 537
             K + + ++   W K   P+    R+ V        L++ +    D G Y         T 
Sbjct: 13635 KGKPAPSV--SWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTK 13692

Query: 538   PA--KVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGS 595
                  + V+  P I    +  D  VT  A       + +   PP     S     I+E  
Sbjct: 13693 EGTISIKVVGKPGIPTGPIKFDE-VTAEA-------MTLKWAPPKDDGGSEITNYILEKR 13744

Query: 596   GRIRTE-----SYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVV-----DFP 645
               +  +     S    +T  +          + ++ +N+ G         +V     D P
Sbjct: 13745 DSVNNKWVTCASAVQKTTFRVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVP 13804

Query: 646   DPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFE 705
             D P  P + +V  D   + W  P   GGSPI GY +E K++ S  W R N    +   F+
Sbjct: 13805 DAPPPPNIVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTPIRMRDFK 13864

Query: 706   PKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRP 765
                + EG+ YE R+ A+N  G+ KPS+PS P V L    PP    V ++T  +VT+ W  
Sbjct: 13865 VTGLTEGLEYEFRVMAINLAGVGKPSLPSEPVVALDPIDPPGKPEVINITRNSVTLIWTE 13924

Query: 766   PDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGA 825
             P + G   L GY++E     ++ W+ AN   + +  FT+T L    K   R++A N AGA
Sbjct: 13925 PKYDGGHKLTGYIVEKRDLPSKSWMKANHVNVPECAFTVTDLVEGGKYEFRIRAKNTAGA 13984

Query: 826   -SEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNL-VIPFQGKPRPELTWKKD 883
              S P   ++ I+ K+  E P I +   +K     + G+ + L  I   GKP P+ +W K 
Sbjct: 13985 ISAPSESTETIICKDEYEAPTIVLDPTIKDGLTIKAGDTIVLNAISILGKPLPKSSWSKA 14044

Query: 884   GAEIDKNQI-NIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPP 942
             G +I  + I  I ++ T +++ I+ A R  +G+Y +        +   + + ++D PGPP
Sbjct: 14045 GKDIRPSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFGTKVEHVKVTVLDVPGPP 14104

Query: 943   QIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITEL 1002
               V+I +V  E   LTWTPP +DG + I  Y ++K +   + W  V E         T+L
Sbjct: 14105 GPVEISNVSAEKATLTWTPPLEDGGSPIKSYILEKRETSRLLWTVVSEDIQSCRHVATKL 14164

Query: 1003  VIGNEYYFRVFSENMCGLSE 1022
             + GNEY FRV + N  G  E
Sbjct: 14165 IQGNEYIFRVSAVNHYGKGE 14184



 Score =  228 bits (580), Expect = 3e-59
 Identities = 170/617 (27%), Positives = 288/617 (46%), Gaps = 47/617 (7%)

Query: 453   VDLKPLKILTPLTDQTV-NLGKEICLKCEISENIPG--KWTKNGLPVQESDRLKVVHKGR 509
             V+   +K+     D  +   G+   L+ ++S   P   +W+K+G  ++ + +L++     
Sbjct: 15084 VEAPKIKVDVKFKDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADF 15143

Query: 510   IHKLVIANALTEDEGDYV--------FAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVT 561
                LV  ++   D G Y         FA   +NV       V+D P       +    VT
Sbjct: 15144 STNLVNKDSTRRDSGAYTLTATNPGGFAKHIFNVK------VLDRP----GPPEGPLAVT 15193

Query: 562   VIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIR-----TESYPDSSTLVIDIAER 616
              +   K  L    S  PP     ++ D  I++     R       S    + L +    +
Sbjct: 15194 EVTSEKCVL----SWFPPLDDGGAKIDHYIVQKRETSRLAWTNVASEVQVTKLKVTKLLK 15249

Query: 617   DDSGVYHINLKNEAG-----EAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYD 671
              +  ++ +   N+ G     E+   + V     PDPP  P VT +  D  ++ W  P  D
Sbjct: 15250 GNEYIFRVMAVNKYGVGEPLESEPVLAVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDSD 15309

Query: 672   GGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPS 731
             GGS I+ Y +ER+ K   RW++ N     +  ++   + EG  YE RI A NA GIS PS
Sbjct: 15310 GGSEIINYIVERRDKAGQRWIKCNKKTLTDLRYKVSGLTEGHEYEFRIMAENAAGISAPS 15369

Query: 732   MPSRPFVPLAVT----SPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTE 787
              P+ PF     T     PP    V   + +++++ W  P + G + + GY++E      +
Sbjct: 15370 -PTSPFYKACDTVFKPGPPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIALPEED 15428

Query: 788   DW-IVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKI 846
             +W IV     +  T +TITGL  + +  +R+ A+N+ G  EP         ++ + PP+I
Sbjct: 15429 EWQIVTPPAGLKATSYTITGLTENQEYKIRIYAMNSEGLGEPALVPGTPKAEDRMLPPEI 15488

Query: 847   RIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKD-GAEIDKNQINIRNSETDTIIFI 905
              +   L++    R    + L +P +G+P PE+ W +D G  +DK   +I ++ + T++ +
Sbjct: 15489 ELDADLRKVVTIRACCTLRLFVPIKGRPAPEVKWARDHGESLDK--ASIESTSSYTLLIV 15546

Query: 906   RKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDD 965
                 R  SGKY L V+     ++A ++++++D PGPPQ +K+++V   +V LTW PP  D
Sbjct: 15547 GNVNRFDSGKYILTVENSSGSKSAFVNVRVLDTPGPPQDLKVKEVTKTSVTLTWDPPLLD 15606

Query: 966   GNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGL---SE 1022
             G + I  Y ++K +     + TV  + H+TS  + +L  G  YYFRV +EN  G+   +E
Sbjct: 15607 GGSKIKNYIVEKRESTRKAYSTVATNCHKTSWKVDQLQEGCSYYFRVLAENEYGIGLPAE 15666

Query: 1023  DATMTKESAVIARDGKI 1039
              A   K S      GKI
Sbjct: 15667 TAESVKASERPLPPGKI 15683



 Score =  228 bits (580), Expect = 3e-59
 Identities = 151/547 (27%), Positives = 256/547 (46%), Gaps = 24/547 (4%)

Query: 489   WTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPD--AYNVTLPAKVHVIDP 546
             W K+GLP++ES+ ++         L I NA  E  G Y    D     + +P  V  + P
Sbjct: 21225 WLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGGKYTVILDNAVCRIAVPITVITLGP 21284

Query: 547   PK-----IILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTE 601
             P      I  D + AD+ +       L  ++P          +S   +   + + ++   
Sbjct: 21285 PSKPKGPIRFDEIKADSVI-------LSWDVPEDNGGGEITCYSIEKRETSQTNWKMVCS 21337

Query: 602   SYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVD-----FPDPPVAPTVTEV 656
             S   ++  V ++  +D    + +  +N  G +   +   +V       P PP  P +  V
Sbjct: 21338 SVARTTFKVPNLV-KDAEYQFRVRAENRYGVSQPLVSSIIVAKHQFRIPGPPGKPVIYNV 21396

Query: 657   GDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYE 716
               D   + W+ P YDGGS + G+ +E+K++ S  W ++N        +    ++EG+ Y+
Sbjct: 21397 TSDGMSLTWDAPVYDGGSEVTGFHVEKKERNSILWQKVNTSPISGREYRATGLVEGLDYQ 21456

Query: 717   VRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDG 776
              R++A N+ G+S PS PS+  + ++   PP       VT  T+T++W PP   G + + G
Sbjct: 21457 FRVYAENSAGLSSPSDPSKFTLAVSPVDPPGTPDYIDVTRETITLKWNPPLRDGGSKIVG 21516

Query: 777   YVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGA-SEPKYYSQPI 835
             Y +E   +G E W+  N   + + ++T+TGL    +   R+ A NA G  S P   S  I
Sbjct: 21517 YSIEK-RQGNERWVRCNFTDVSECQYTVTGLSPGDRYEFRIIARNAVGTISPPSQSSGII 21575

Query: 836   LVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKN-QINI 894
             + ++   PP +          I + GE++ +    QG+P P +TW KDG EI+K   + I
Sbjct: 21576 MTRDENVPPIVEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEI 21635

Query: 895   RNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGP-PQIVKIEDVWGE 953
              +    T +F+R A R H G Y ++ K       A I +++ D PG     ++  ++ GE
Sbjct: 21636 TDVLGSTSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQDTPGKVVGPIRFTNITGE 21695

Query: 954   NVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVF 1013
              + L W  P +DG A IT Y I+K +   + W  + +     S T  +L+ GNEY FRV 
Sbjct: 21696 KMTLWWDAPLNDGCAPITHYIIEKRETSRLAWALIEDKCEAQSYTAIKLINGNEYQFRVS 21755

Query: 1014  SENMCGL 1020
             + N  G+
Sbjct: 21756 AVNKFGV 21762



 Score =  227 bits (578), Expect = 6e-59
 Identities = 154/500 (30%), Positives = 249/500 (49%), Gaps = 18/500 (3%)

Query: 530   PDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDK 589
             P   N  + AK  +++ P+I LD +    +V   AG  +++ IP  G PPP   W R D+
Sbjct: 20881 PIEMNEPVQAK-DILEAPEIDLD-VALRTSVIAKAGEDVQVLIPFKGRPPPTVTW-RKDE 20937

Query: 590   AIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHAS-IKVKVVDFPDPP 648
               +    R   E+   SS L I    R+D+G Y + ++N  GE  +S + VKV+D P   
Sbjct: 20938 KNLGSDARYSIENTDSSSLLTIPQVTRNDTGKYILTIENGVGEPKSSTVSVKVLDTPAAC 20997

Query: 649   VAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKK 708
                 V  V      + W+PP  DGGSPI+ Y IE++      W  ++   C  T+F+   
Sbjct: 20998 QKLQVKHVSRGTVTLLWDPPLIDGGSPIINYVIEKRDATKRTWSVVSHK-CSSTSFKLID 21056

Query: 709   MIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDH 768
             + E   +  R+ A N IGI +P   + P     V +P   L++   T T+V + W  PD 
Sbjct: 21057 LSEKTPFFFRVLAENEIGIGEPCETTEPVKAAEVPAPIRDLSMKDSTKTSVILSWTKPDF 21116

Query: 769   IGAAGLDGYVLEYCFEGTEDWIVANKDLIDKT-KFTITGLPTDAKIFVRVKAVNAAGASE 827
              G + +  YV+E   +G + W  A    I KT +  ++ L   + +  RV A N  G S+
Sbjct: 21117 DGGSVITEYVVERKGKGEQTWSHAG---ISKTCEIEVSQLKEQSVLEFRVFAKNEKGLSD 21173

Query: 828   PKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEI 887
             P     PI VKE+I  P++ +          R+G  V+L +P++GKP+P ++W KDG  +
Sbjct: 21174 PVTIG-PITVKELIITPEVDLSDIPGAQVTVRIGHNVHLELPYKGKPKPSISWLKDGLPL 21232

Query: 888   DKNQ-INIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQI-- 944
              +++ +    +E    + I+ A++ H GKY   V +D  V   ++ I +I   GPP    
Sbjct: 21233 KESEFVRFSKTENKITLSIKNAKKEHGGKYT--VILDNAVCRIAVPITVITL-GPPSKPK 21289

Query: 945   --VKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITEL 1002
               ++ +++  ++V L+W  P+D+G   IT Y+I+K +     W  V     RT+  +  L
Sbjct: 21290 GPIRFDEIKADSVILSWDVPEDNGGGEITCYSIEKRETSQTNWKMVCSSVARTTFKVPNL 21349

Query: 1003  VIGNEYYFRVFSENMCGLSE 1022
             V   EY FRV +EN  G+S+
Sbjct: 21350 VKDAEYQFRVRAENRYGVSQ 21369



 Score =  226 bits (576), Expect = 1e-58
 Identities = 163/554 (29%), Positives = 261/554 (47%), Gaps = 33/554 (5%)

Query: 489   WTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYV--FAPDAYNVTLPAKVHVIDP 546
             W K+ +P++++ R+          L I +A  ED G YV      A        V V+D 
Sbjct: 15809 WHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAGEAIETLNVIVLDK 15868

Query: 547   P-----KIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTE 601
             P      + +D + AD+             I +S  PP     S  +  I+E      T 
Sbjct: 15869 PGPPTGPVKMDEVTADS-------------ITLSWGPPKYDGGSSINNYIVEKRDTSTTT 15915

Query: 602   SYPDSSTLVIDI--AERDDSGV---YHINLKNEAGEA-HASIKVKVVDF----PDPPVAP 651
                 S+T+      A R  +G    + I  +N  G++ + + +  V  +    P PP  P
Sbjct: 15916 WQIVSATVARTTIKACRLKTGCEYQFRIAAENRYGKSTYLNSEPTVAQYPFKVPGPPGTP 15975

Query: 652   TVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIE 711
              VT    D   + W  P  DGGS ++GY +ERK++ S  W++LN     +T F+   + E
Sbjct: 15976 VVTLSSRDSMEVQWNEPISDGGSRVIGYHLERKERNSILWVKLNKTPIPQTKFKTTGLEE 16035

Query: 712   GVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGA 771
             GV YE R+ A N +GI KPS  S  +V      PP       VT  +VT++W+ P + G 
Sbjct: 16036 GVEYEFRVSAENIVGIGKPSKVSECYVARDPCDPPGRPEAIIVTRNSVTLQWKKPTYDGG 16095

Query: 772   AGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGA-SEPKY 830
             + + GY++E        W+ A+   I  T F +TGL  D +   RV A NAAG  SEP  
Sbjct: 16096 SKITGYIVEKKELPEGRWMKASFTNIIDTHFEVTGLVEDHRYEFRVIARNAAGVFSEPSE 16155

Query: 831   YSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKN 890
              +  I  ++ ++PP+I +    K T +   GE+  +     GKP P + W K   E+   
Sbjct: 16156 STGAITARDEVDPPRISMDPKYKDTIVVHAGESFKVDADIYGKPIPTIQWIKGDQELSNT 16215

Query: 891   -QINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQ-IVKIE 948
              ++ I++++  T + ++ A R  SG Y L+ K      + +++++++DRPGPP+  V I 
Sbjct: 16216 ARLEIKSTDFATSLSVKDAVRVDSGNYILKAKNVAGERSVTVNVKVLDRPGPPEGPVVIS 16275

Query: 949   DVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEY 1008
              V  E   L W PP  DG + I  Y +++ +   + W  V  +    S  +T+L+ GNEY
Sbjct: 16276 GVTAEKCTLAWKPPLQDGGSDIINYIVERRETSRLVWTVVDANVQTLSCKVTKLLEGNEY 16335

Query: 1009  YFRVFSENMCGLSE 1022
              FR+ + N  G+ E
Sbjct: 16336 TFRIMAVNKYGVGE 16349



 Score =  225 bits (574), Expect = 2e-58
 Identities = 142/476 (29%), Positives = 224/476 (47%), Gaps = 18/476 (3%)

Query: 598   IRTESYPDSSTLVIDIAERDDSGVYHINLKNEAG-----EAHASIKVKVVDFPDPPVAPT 652
             +   S P   T  I         V+ I  +N+ G     ++       +   P  P  PT
Sbjct: 9893  VHVSSEPKECTYTIPKLLEGHEYVFRIMAQNKYGIGEPLDSEPETARNLFSVPGAPDKPT 9952

Query: 653   VTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETT----FEPKK 708
             V+ V  +   +NWE P YDGGSP+ GY++E K   S RW R+N D  K  T    ++   
Sbjct: 9953  VSSVTRNSMTVNWEEPEYDGGSPVTGYWLEMKDTTSKRWKRVNRDPIKAMTLGVSYKVTG 10012

Query: 709   MIEGVAYEVRIFAVNAIGISKPSMPSRPFV---PLAVTSPPTLLTVDSVTDTTVTMRWRP 765
             +IEG  Y+ R++A+NA G+   S+PS P     P+A   PP     D  T ++  + W P
Sbjct: 10013 LIEGSDYQFRVYAINAAGVGPASLPSDPATARDPIAPPGPPFPKVTDW-TKSSADLEWSP 10071

Query: 766   PDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGA 825
             P   G + + GY++EY  EG E+W       +  TK  +TGL   A    RV+AVN AG 
Sbjct: 10072 PLKDGGSKVTGYIVEYKEEGKEEWEKGKDKEVRGTKLVVTGLKEGAFYKFRVRAVNIAGI 10131

Query: 826   SEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGA 885
              EP   +  I +K+ +  P +++   ++   +   G  + ++    GKP P +TW  +  
Sbjct: 10132 GEPGEVTDVIEMKDRLVSPDLQLDASVRDRIVVHAGGVIRIIAYVSGKPPPTVTWNMNER 10191

Query: 886   EIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIV 945
              + + +  I  +   + + I+  +RSH G Y L  K +      +I + ++D PGP    
Sbjct: 10192 TLPQ-EATIETTAISSSMVIKNCQRSHQGVYSLLAKNEAGERKKTIIVDVLDVPGPVGTP 10250

Query: 946   KI-EDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVI 1004
              +  ++  E+  LTW  P+DDG + IT Y I+K +     W  V     R +AT+  L+ 
Sbjct: 10251 FLAHNLTNESCKLTWFSPEDDGGSPITNYVIEKRESDRRAWTPVTYTVTRQNATVQGLIQ 10310

Query: 1005  GNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPL 1060
             G  Y+FR+ +EN  G+      T E+ VI     + + P  ED +  E    T  L
Sbjct: 10311 GKAYFFRIAAENSIGMG-PFVETSEALVIREPITVPERP--EDLEVKEVTKNTVTL 10363



 Score =  223 bits (569), Expect = 6e-58
 Identities = 160/574 (27%), Positives = 265/574 (46%), Gaps = 34/574 (5%)

Query: 488   KWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNV----TLPAKVHV 543
             +W K    +  + RL++        L + +A+  D G+Y+    A NV    ++   V V
Sbjct: 16204 QWIKGDQELSNTARLEIKSTDFATSLSVKDAVRVDSGNYILK--AKNVAGERSVTVNVKV 16261

Query: 544   IDPP-----KIILDGLDADNTVTVIA-----GNKLRLEIPISGEPPPKAMWSRGDKAIME 593
             +D P      +++ G+ A+            G    +   +      + +W+  D  +  
Sbjct: 16262 LDRPGPPEGPVVISGVTAEKCTLAWKPPLQDGGSDIINYIVERRETSRLVWTVVDANVQT 16321

Query: 594   GSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTV 653
              S ++      +  T  I    +   G        E  E+   +       PD P AP V
Sbjct: 16322 LSCKVTKLLEGNEYTFRIMAVNKYGVG--------EPLESEPVVAKNPFVVPDAPKAPEV 16373

Query: 654   TEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGV 713
             T V  D  I+ WE PA DGGS ILGY +E++ K+  RW R +  L  E       +IE  
Sbjct: 16374 TTVTKDSMIVVWERPASDGGSEILGYVLEKRDKEGIRWTRCHKRLIGELRLRVTGLIENH 16433

Query: 714   AYEVRIFAVNAIGISKPSMPS---RPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIG 770
              YE R+ A NA G+S+PS PS   +   P+    PP    V  +T ++V + W  P + G
Sbjct: 16434 DYEFRVSAENAAGLSEPSPPSAYQKACDPIYKPGPPNNPKVIDITRSSVFLSWSKPIYDG 16493

Query: 771   AAGLDGYVLEYCFEGTEDWIVANKDL-IDKTKFTITGLPTDAKIFVRVKAVNAAGASEPK 829
                + GY++E C     +W +      I+KT   +  L    +   R+ A+N AG  E  
Sbjct: 16494 GCEIQGYIVEKCDVSVGEWTMCTPPTGINKTNIEVEKLLEKHEYNFRICAINKAGVGEHA 16553

Query: 830   YYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTW-KKDGAEID 888
                 PI+V+E +E P I +   L++    R G ++ L +P +G+P PE+ W K DG   D
Sbjct: 16554 DVPGPIIVEEKLEAPDIDLDLELRKIINIRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRD 16613

Query: 889   KNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIE 948
                I++ +S T  +  +    R  SGKY L ++     ++A + ++++D P PP  +K+ 
Sbjct: 16614 AAIIDVTSSFTSLV--LDNVNRYDSGKYTLTLENSSGTKSAFVTVRVLDTPSPPVNLKVT 16671

Query: 949   DVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEY 1008
             ++  ++V++TW PP  DG + I  Y ++K +     +  V+ + H+ S  I +L  G  Y
Sbjct: 16672 EITKDSVSITWEPPLLDGGSKIKNYIVEKREATRKSYAAVVTNCHKNSWKIDQLQEGCSY 16731

Query: 1009  YFRVFSENMCGL---SEDATMTKESAVIARDGKI 1039
             YFRV +EN  G+   ++ A   K + V    GKI
Sbjct: 16732 YFRVTAENEYGIGLPAQTADPIKVAEVPQPPGKI 16765



 Score =  222 bits (566), Expect = 1e-57
 Identities = 161/583 (27%), Positives = 256/583 (43%), Gaps = 22/583 (3%)

Query: 455   LKPLKILTPLTDQTVNLGKEICLKCEI--SENIPGKWTKNGLPVQESDRLKVVHKGRIHK 512
             L P KIL P    T+  GK++ ++  +    +   KW K    V  S  L V        
Sbjct: 12525 LLPPKILMP-EQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSI 12583

Query: 513   LVIANALTEDEGDYVFAPDAYNVTLPAKVHVI-----DPPKIILDGLDADNTVTVIAGNK 567
             L+I +   +D G Y    +  + T   K+ V+      PP+   D  D D          
Sbjct: 12584 LIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPGPPQPPFDISDIDADAC-----S 12638

Query: 568   LRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLK 627
             L   IP+         +      +  G       S   +S  V  +    +  ++ +  +
Sbjct: 12639 LSWHIPLEDGGSNITNYIVEKCDVSRGDWVTALASVTKTSCRVGKLIPGQEY-IFRVRAE 12697

Query: 628   NEAGEAHASIKVKVV-----DFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIE 682
             N  G +      K+V       P  P    VT+V  D   + W+ P  DGGSPI+GY IE
Sbjct: 12698 NRFGISEPLTSPKMVAQFPFGVPSEPKNARVTKVNKDCIFVAWDRPDSDGGSPIIGYLIE 12757

Query: 683   RKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAV 742
             RK++ S  W++ N  L + T +    ++EG+ Y  RI+A+N  G S PS P+        
Sbjct: 12758 RKERNSLLWVKANDTLVRSTEYPCAGLVEGLEYSFRIYALNKAGSSPPSKPTEYVTARMP 12817

Query: 743   TSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVAN--KDLIDKT 800
               PP    V  VT +TV++ W  P H G + + GY +E C    + W+  N     I + 
Sbjct: 12818 VDPPGKPEVIDVTKSTVSLIWARPKHDGGSKIIGYFVEACKLPGDKWVRCNTAPHQIPQE 12877

Query: 801   KFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRV 860
             ++T TGL   A+   R  A  A   S P   S P+ +     PP+I +   +K     + 
Sbjct: 12878 EYTATGLEEKAQYQFRAIARTAVNISPPSEPSDPVTILAENVPPRIDLSVAMKSLLTVKA 12937

Query: 861   GEAVNLVIPFQGKPRPELTWKKDGAEIDKNQ-INIRNSETDTIIFIRKAERSHSGKYDLQ 919
             G  V L     GKP P ++WKKDG  +   + I +        + +    R  SG Y + 
Sbjct: 12938 GTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTIT 12997

Query: 920   VKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKAD 979
              +     ++A+I ++++D+PGPP  VKI  ++ +   L+W PP +DG + IT Y + K +
Sbjct: 12998 AENSSGSKSATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYIVDKRE 13057

Query: 980   KKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSE 1022
                  W  V      TS ++ +L+ G+EY FR+ +EN  G+ +
Sbjct: 13058 TSRPNWAQVSATVPITSCSVEKLIEGHEYQFRICAENKYGVGD 13100



 Score =  222 bits (565), Expect = 2e-57
 Identities = 160/535 (29%), Positives = 257/535 (48%), Gaps = 52/535 (9%)

Query: 527  VFAPDAYNVTLPAKV--HVI--DP---PKIILDGLDADNTVTVIAGNKLRLEIPISGEPP 579
            V A +A  V+ P+++  +V+  DP   P I L+  D    + VI G KL + +P    P 
Sbjct: 7988 VRAVNAIGVSEPSEISENVVAKDPDCKPTIDLETHD----IIVIEGEKLSIPVPFRAVPV 8043

Query: 580  PKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKV 639
            P   W +  K + + S R+  ++   S+ L +  + R D+G+Y I L+N+ G A ASI V
Sbjct: 8044 PTVSWHKDGKEV-KASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATASINV 8102

Query: 640  KVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLC 699
            KV+  P P      +++    C + WEPP +DGG+PIL Y +ER++     ++ +     
Sbjct: 8103 KVIGLPGPCKDIKASDITKSSCKLTWEPPEFDGGTPILHYVLERREAGRRTYIPVMSGEN 8162

Query: 700  KETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFV---PLAVTSPPTLLTVDSVTD 756
            K  ++  K +I    Y  R+ AVN +G  +      P +   P     PP  + V + T 
Sbjct: 8163 K-LSWTVKDLIPNGEYFFRVKAVNKVGGGEYIELKNPVIAQDPKQPPDPPVDVEVHNPTA 8221

Query: 757  TTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVR 816
              +T+ W+PP + G + + GY++E   +G E W   N+ L+    +T  GL    +   R
Sbjct: 8222 EAMTITWKPPLYDGGSKIMGYIIEKIAKGEERWKRCNEHLVPILTYTAKGLEEGKEYQFR 8281

Query: 817  VKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRP 876
            V+A NAAG SEP   + P    + I+ PK+ +   L+   ++R G+ + L     G P P
Sbjct: 8282 VRAENAAGISEPSRATPPTKAVDPIDAPKVILRTSLE---VKR-GDEIALDASISGSPYP 8337

Query: 877  ELTWKKD-----GAEIDK------------------------NQINIRNSET-DTIIFIR 906
             +TW KD       EI K                         +++I NS+  ++ + +R
Sbjct: 8338 TITWIKDENVIVPEEIKKRAAPLVRRRKGEVQEEEPFVLPLTQRLSIDNSKKGESQLRVR 8397

Query: 907  KAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDG 966
             + R   G Y ++V+ D  +  A   + ++D PGPP     ED+   +V   W PP DDG
Sbjct: 8398 DSLRPDHGLYMIKVENDHGIAKAPCTVSVLDTPGPPINFVFEDIRKTSVLCKWEPPLDDG 8457

Query: 967  NAAITGYTIQKAD--KKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCG 1019
             + I  YT++K D  K   EW  V         ++T+L+ G EY FRV +EN  G
Sbjct: 8458 GSEIINYTLEKKDKTKPDSEWIVVTSTLRHCKYSVTKLIEGKEYLFRVRAENRFG 8512



 Score =  220 bits (561), Expect = 5e-57
 Identities = 176/654 (26%), Positives = 292/654 (44%), Gaps = 63/654 (9%)

Query: 405   EIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPL 464
             +++ G K  +RIR +         GA  A +     +    +  A       P  +L P 
Sbjct: 13965 DLVEGGKYEFRIRAKNTA------GAISAPSESTETIICKDEYEA-------PTIVLDPT 14011

Query: 465   TDQ--TVNLGKEICLKCE--ISENIP-GKWTKNGLPVQESDRLKVVHKGRIHKLVIANAL 519
                  T+  G  I L     + + +P   W+K G  ++ SD  ++        L I  A 
Sbjct: 14012 IKDGLTIKAGDTIVLNAISILGKPLPKSSWSKAGKDIRPSDITQITSTPTSSMLTIKYAT 14071

Query: 520   TEDEGDY-VFAPDAYNVTLP-AKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGE 577
              +D G+Y + A + +   +   KV V+D P     G      ++ ++  K  L    +  
Sbjct: 14072 RKDAGEYTITATNPFGTKVEHVKVTVLDVP-----GPPGPVEISNVSAEKATL----TWT 14122

Query: 578   PPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLK----NE---- 629
             PP +   S     I+E           ++S L+  +   D     H+  K    NE    
Sbjct: 14123 PPLEDGGSPIKSYILEKR---------ETSRLLWTVVSEDIQSCRHVATKLIQGNEYIFR 14173

Query: 630   --------AGEAHASIKVKVVDF---PDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILG 678
                      GE   S  VK+VD    P PP  P V+ V  +   ++W+ P  DGGS I G
Sbjct: 14174 VSAVNHYGKGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSWKRPVDDGGSEITG 14233

Query: 679   YFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFV 738
             Y +ER++K+S RW+R       +   +   + EG  YE R+ A N  GI  PS  S   +
Sbjct: 14234 YHVERREKKSLRWVRAIKTPVSDLRCKVTGLQEGSTYEFRVSAENRAGIGPPSEASDSVL 14293

Query: 739   PLAVTSPPTLLTVDSVTDTT---VTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIV-ANK 794
                   PP   +   VTDTT    ++ W  P + G   + GYV+E+   G E WI     
Sbjct: 14294 MKDAAYPPGPPSNPHVTDTTKKSASLAWGKPHYDGGLEITGYVVEHQKVGDEAWIKDTTG 14353

Query: 795   DLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQ 854
               +  T+F +  L T  K   R+ A+N AG  EP       +V+  + P    +   L++
Sbjct: 14354 TALRITQFVVPDLQTKEKYNFRISAINDAGVGEPAVIPDVEIVEREMAPD-FELDAELRR 14412

Query: 855   TYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSG 914
             T + R G ++ + +P +G+P PE+TW KD   + KN+ NI N+E+ T++ I +  R  +G
Sbjct: 14413 TLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINL-KNRANIENTESFTLLIIPECNRYDTG 14471

Query: 915   KYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYT 974
             K+ + ++     ++  ++++++D PGP   ++  D+  ++V L W  P  DG + IT Y 
Sbjct: 14472 KFVMTIENPAGKKSGFVNVRVLDTPGPVLNLRPTDITKDSVTLHWDLPLIDGGSRITNYI 14531

Query: 975   IQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTK 1028
             ++K +     + T     H+ +  +T L  G EY+FRV +EN  G+ E    T+
Sbjct: 14532 VEKREATRKSYSTATTKCHKCTYKVTGLSEGCEYFFRVMAENEYGIGEPTETTE 14585



 Score =  218 bits (554), Expect = 3e-56
 Identities = 159/598 (26%), Positives = 266/598 (44%), Gaps = 55/598 (9%)

Query: 459   KILTPLTDQTVNLGKEICLKCEISENIPG----------KWTKNGLPVQESDRLKVVHKG 508
             K++ P  +  V L + + +K   +   P           KWT +G  ++  +   V    
Sbjct: 11132 KLVPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDN 11191

Query: 509   RIHKLVIANALTEDEGDYVFAPD--AYNVTLPAKVHVID---PPKIILDGLDADNTVTVI 563
                 L I N L  D G+Y       A + T+   + V+D   PP   ++ LD        
Sbjct: 11192 FSSVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTVLDVPGPPTGPINILDVTPE---- 11247

Query: 564   AGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIR-----TESYPDSSTLVIDIAERDD 618
                     + IS +PP     S     I+E     +       S    + L I   ++  
Sbjct: 11248 -------HMTISWQPPKDDGGSPVINYIVEKQDTRKDTWGVVSSGSSKTKLKIPHLQKGC 11300

Query: 619   SGVYHINLKNEAG-----EAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGG 673
               V+ +  +N+ G     ++  ++       P PP  P VT++ ++   ++W  P  DGG
Sbjct: 11301 EYVFRVRAENKIGVGPPLDSTPTVAKHKFSPPSPPGKPVVTDITENAATVSWTLPKSDGG 11360

Query: 674   SPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMP 733
             SPI GY++ER++  + +W+R+N     +  F    + EG  YE R+FA N  G+SKPS  
Sbjct: 11361 SPITGYYMERREV-TGKWVRVNKTPIADLKFRVTGLYEGNTYEFRVFAENLAGLSKPSPS 11419

Query: 734   SRPFV---PLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWI 790
             S P     P+    PP    +   +  T  + W  P   G + + GYV+E    GT  W 
Sbjct: 11420 SDPIKACRPIKPPGPPINPKLKDKSRETADLVWTKPLSDGGSPILGYVVECQKPGTAQWN 11479

Query: 791   VANKD-LIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIP 849
               NKD LI +  F + GL    +   R+KA N  G  EP+  ++ ++ K+I+ PP++ + 
Sbjct: 11480 RINKDELIRQCAFRVPGLIEGNEYRFRIKAANIVGEGEPRELAESVIAKDILHPPEVELD 11539

Query: 850   RHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTI------- 902
                +     RVG+ + ++   +G+P P++TW K+G      ++ +R    D I       
Sbjct: 11540 VTCRDVITVRVGQTIRILARVKGRPEPDITWTKEG------KVLVREKRVDLIQDLPRVE 11593

Query: 903   IFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPP 962
             + I++A R+  GKY +  K        S  + ++DRPGP Q +K+ +V  EN  ++W  P
Sbjct: 11594 LQIKEAVRADHGKYIISAKNSSGHAQGSAIVNVLDRPGPCQNLKVTNVTKENCTISWENP 11653

Query: 963   KDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGL 1020
              D+G + IT + ++        W  V     +       L+  NEYYFRV +EN  G+
Sbjct: 11654 LDNGGSEITNFIVEYRKPNQKGWSIVASDVTKRLIK-ANLLANNEYYFRVCAENKVGV 11710



 Score =  214 bits (544), Expect = 5e-55
 Identities = 128/407 (31%), Positives = 204/407 (50%), Gaps = 22/407 (5%)

Query: 636  SIKVKVVD---FPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWM 692
            S KV + D    P PP  P V        +++W PP  +GGSPI GY++E++++ S  W 
Sbjct: 9215 SDKVVIQDPYRLPGPPGKPKVLARTKGSMLVSWTPPLDNGGSPITGYWLEKREEGSPYWS 9274

Query: 693  RLNFDLC-----KETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFV---PLAVTS 744
            R++         K   F   +++EGV Y+ R  A+NA GI  PS PS P V   P+    
Sbjct: 9275 RVSRAPITKVGLKGVEFNVPRLLEGVKYQFRAMAINAAGIGPPSEPSDPEVAGDPIFPPG 9334

Query: 745  PPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKD--LIDKTKF 802
            PP+   V   T +++++ W+PP   G + + GY++E   EGT DW   N+   LI   + 
Sbjct: 9335 PPSCPEVKDKTKSSISLGWKPPAKDGGSPIKGYIVEMQEEGTTDWKRVNEPDKLITTCEC 9394

Query: 803  TITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGE 862
             +  L    K   RVKAVN AG SEP   +  I   +I E P++ I    +   + + G 
Sbjct: 9395 VVPNLKELRKYRFRVKAVNEAGESEPSDTTGEIPATDIQEEPEVFIDIGAQDCLVCKAGS 9454

Query: 863  AVNLVIPFQGKPRPELTWK---------KDGAEIDKNQINIRNSETDTIIFIRKAERSHS 913
             + +    +G+P P+ +W+         KDG         +  +E  ++I I + +RSH+
Sbjct: 9455 QIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECKRSHT 9514

Query: 914  GKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGY 973
            GKY +  K     +TA+  ++++D PGPP+ +K+ D+   +  L+W  P DDG   I GY
Sbjct: 9515 GKYSITAKNKAGQKTANCRVKVMDVPGPPKDLKVSDITRGSCRLSWKMPDDDGGDRIKGY 9574

Query: 974  TIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGL 1020
             I+K       W  V      T+  + +L+   +Y+FRV +EN  G+
Sbjct: 9575 VIEKRTIDGKAWTKVNPDCGSTTFVVPDLLSEQQYFFRVRAENRFGI 9621



 Score =  214 bits (544), Expect = 5e-55
 Identities = 163/595 (27%), Positives = 269/595 (45%), Gaps = 44/595 (7%)

Query: 468   TVNLGKEICLKCEISENIPGK--WTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGD 525
             T+  G ++ L   +      K  WTK    +   +++ + + G+    VI      D G 
Sbjct: 22686 TIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSGK 22745

Query: 526   YVFAPDAYNVT--LPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPP---- 579
             Y       + T  +   V V+D P     G     TV+ +   K  L   +  E      
Sbjct: 22746 YTLTVKNASGTKAVSVMVKVLDSP-----GPCGKLTVSRVTQEKCTLAWSLPQEDGGAEI 22800

Query: 580   -----PKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAG--- 631
                   +   SR +  I+EG     T SY      V+    +++  ++ +   N+ G   
Sbjct: 22801 THYIVERRETSRLNWVIVEGE--CPTLSY------VVTRLIKNNEYIFRVRAVNKYGPGV 22852

Query: 632   --EAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSS 689
               E+   +       P PP  P     G +  I+ W  P  DGG+ I  Y +++++K+S 
Sbjct: 22853 PVESEPIVARNSFTIPSPPGIPEEVGTGKEHIIIQWTKPESDGGNEISNYLVDKREKKSL 22912

Query: 690   RWMRLNFD-LCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFV----PLAVTS 744
             RW R+N D +  +T  +   ++EG  Y+ R+ AVNA G S+PS  S  F+    P     
Sbjct: 22913 RWTRVNKDYVVYDTRLKVTSLMEGCDYQFRVTAVNAAGNSEPSEASN-FISCREPSYTPG 22971

Query: 745   PPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWI-VANKDLIDKTKFT 803
             PP+   V   T  ++++ W  P + G   + GYVLE   + T+ W  V     I  T+FT
Sbjct: 22972 PPSAPRVVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDTDQWYRVHTNATIRNTEFT 23031

Query: 804   ITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEA 863
             +  L    K   RV AVN  G SE       I   E IE P + +   LK+T   R G +
Sbjct: 23032 VPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEIPDLELADDLKKTVTIRAGAS 23091

Query: 864   VNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVD 923
             + L++   G+P P +TW K G ++    I I  +E+ +++ + K  R  +GKY ++ +  
Sbjct: 23092 LRLMVSVSGRPPPVITWSKQGIDLASRAI-IDTTESYSLLIVDKVNRYDAGKYTIEAENQ 23150

Query: 924   KFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSM 983
                ++A++ +++ D PGP   VK+++V  ++V +TW  P  DG A +  Y ++K +    
Sbjct: 23151 SGKKSATVLVKVYDTPGPCPSVKVKEVSRDSVTITWEIPTIDGGAPVNNYIVEKREAAMR 23210

Query: 984   EWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSE-----DATMTKESAVI 1033
              + TV     +T   I+ LV G  YYFRV  EN+ G+ E     DA +  E  ++
Sbjct: 23211 AFKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYGIGEPCETSDAVLVSEVPLV 23265



 Score =  213 bits (543), Expect = 6e-55
 Identities = 156/581 (26%), Positives = 275/581 (47%), Gaps = 32/581 (5%)

Query: 469   VNLGKEICLKCEI-SENIPGK-WTKNGLPVQESD-RLKVVHKGRIHKLVIANALTEDEGD 525
             V+ G+   L+ +I  + IP   W+K+G  ++E+  R+++    +   LV+ + +  D G 
Sbjct: 18347 VHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQ 18406

Query: 526   YVFAPDAYNVT--LPAKVHVIDPP-----KIILDGLDAD------NTVTVIAGNKLRLEI 572
             Y+        T  +P  V V+D P      + + G+ A+      N      G  +   I
Sbjct: 18407 YILKLSNVGGTKSIPITVKVLDRPGPPEGPLKVTGVTAEKCYLAWNPPLQDGGANISHYI 18466

Query: 573   PISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGE 632
              I      +  W++    +   + ++ T+  P +  +   +A       Y I    E+G 
Sbjct: 18467 -IEKRETSRLSWTQVSTEVQALNYKV-TKLLPGNEYIFRVMAVNK----YGIGEPLESGP 18520

Query: 633   AHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWM 692
               A    K    P PP  P V+ +  D  ++ W  P  DGG+ I GY +E++ K+  RW 
Sbjct: 18521 VTACNPYKP---PGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDKEGVRWT 18577

Query: 693   RLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVD 752
             + N     +       + EG +YE R+ A NA G+ +PS PS  +       PP   +  
Sbjct: 18578 KCNKKTLTDLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRACDALYPPGPPSNP 18637

Query: 753   SVTDT---TVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDL-IDKTKFTITGLP 808
              VTDT   +V++ W  P + G A + GYV+E      ++W        +   +FT+T L 
Sbjct: 18638 KVTDTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAADEWTTCTPPTGLQGKQFTVTKLK 18697

Query: 809   TDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVI 868
              + +   R+ A+N+ G  EP      ++ +E IEPP+I +   L++  + R    + L +
Sbjct: 18698 ENTEYNFRICAINSEGVGEPATLPGSVVAQERIEPPEIELDADLRKVVVLRASATLRLFV 18757

Query: 869   PFQGKPRPELTWKK-DGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVE 927
               +G+P PE+ W+K +G   D+ QI + +S   T++ I    R  SG+Y+L ++ +   +
Sbjct: 18758 TIKGRPEPEVKWEKAEGILTDRAQIEVTSS--FTMLVIDNVTRFDSGRYNLTLENNSGSK 18815

Query: 928   TASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFT 987
             TA ++++++D P  P  + I +V  ++V L+W PP  DG A IT Y ++K +     + T
Sbjct: 18816 TAFVNVRVLDSPSAPVNLTIREVKKDSVTLSWEPPLIDGGAKITNYIVEKRETTRKAYAT 18875

Query: 988   VIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTK 1028
             +  +  +T+  I  L  G  YYFRV + N  G+   A  T+
Sbjct: 18876 ITNNCTKTTFRIENLQEGCSYYFRVLASNEYGIGLPAETTE 18916



 Score =  213 bits (542), Expect = 8e-55
 Identities = 117/390 (30%), Positives = 208/390 (53%), Gaps = 6/390 (1%)

Query: 645   PDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTF 704
             P PP  P VT++  +   + W  P  DGGS I GYF+E++ K+S  W ++  +  ++T  
Sbjct: 20694 PGPPGIPEVTKITKNSMTVVWSRPIADGGSDISGYFLEKRDKKSLGWFKVLKETIRDTRQ 20753

Query: 705   EPKKMIEGVAYEVRIFAVNAIG---ISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTM 761
             +   + E   Y+ R+ AVNA G    S+PS   +   P+    PP  + +   T +++T+
Sbjct: 20754 KVTGLTENSDYQYRVCAVNAAGQGPFSEPSEFYKAADPIDPPGPPAKIRIADSTKSSITL 20813

Query: 762   RWRPPDHIGAAGLDGYVLEYCFEGTEDWI-VANKDLIDKTKFTITGLPTDAKIFVRVKAV 820
              W  P + G + + GYV+E      E+W  V+ K  +  T++ ++ L      + RV AV
Sbjct: 20814 GWSKPVYDGGSAVTGYVVEIRQGEEEEWTTVSTKGEVRTTEYVVSNLKPGVNYYFRVSAV 20873

Query: 821   NAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTW 880
             N AG  EP   ++P+  K+I+E P+I +   L+ + I + GE V ++IPF+G+P P +TW
Sbjct: 20874 NCAGQGEPIEMNEPVQAKDILEAPEIDLDVALRTSVIAKAGEDVQVLIPFKGRPPPTVTW 20933

Query: 881   KKDGAEIDKN-QINIRNSETDTIIFIRKAERSHSGKYDLQVKVD-KFVETASIDIQIIDR 938
             +KD   +  + + +I N+++ +++ I +  R+ +GKY L ++      +++++ ++++D 
Sbjct: 20934 RKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKYILTIENGVGEPKSSTVSVKVLDT 20993

Query: 939   PGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSAT 998
             P   Q ++++ V    V L W PP  DG + I  Y I+K D     W  V      TS  
Sbjct: 20994 PAACQKLQVKHVSRGTVTLLWDPPLIDGGSPIINYVIEKRDATKRTWSVVSHKCSSTSFK 21053

Query: 999   ITELVIGNEYYFRVFSENMCGLSEDATMTK 1028
             + +L     ++FRV +EN  G+ E    T+
Sbjct: 21054 LIDLSEKTPFFFRVLAENEIGIGEPCETTE 21083



 Score =  210 bits (535), Expect = 5e-54
 Identities = 144/504 (28%), Positives = 232/504 (46%), Gaps = 21/504 (4%)

Query: 545  DPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYP 604
            +PP + LD +     + ++AG  LR+   ++G P P  +W++ +  +     R+  ++  
Sbjct: 8728 EPPAVELD-VSVKGGIQIMAGKTLRIPAVVTGRPVPTKVWTKEEGEL--DKDRVVIDNVG 8784

Query: 605  DSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMN 664
              S L+I  A R D G Y I   N  G   A+ +V+V D P P +           C++N
Sbjct: 8785 TKSELIIKDALRKDHGRYVITATNSCGSKFAAARVEVFDVPGPVLDLKPVVTNRKMCLLN 8844

Query: 665  WEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNA 724
            W  P  DGGS I G+ IERK  +   W R   +  + +  +   ++EG  Y+ R+ A N 
Sbjct: 8845 WSDPEDDGGSEITGFIIERKDAKMHTW-RQPIE-TERSKCDITGLLEGQEYKFRVIAKNK 8902

Query: 725  IGISKPSM--PSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYC 782
             G   P    P     PL   + P  LT    T +T+T+ W+ P   G + + GY++E  
Sbjct: 8903 FGCGPPVEIGPILAVDPLGPPTSPERLTYTERTKSTITLDWKEPRSNGGSPIQGYIIEKR 8962

Query: 783  FEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIE 842
                 D+   NK L   T F +  L        RVKAVN  G SEP      +++++   
Sbjct: 8963 RHDKPDFERVNKRLCPTTSFLVENLDEHQMYEFRVKAVNEIGESEPS-LPLNVVIQDDEV 9021

Query: 843  PPKIRIPRHLKQTYIR-RVGEAVNLVIPFQGKPRPELTWKKDGAEIDK-------NQINI 894
            PP I++   ++   I+ + GE V++     G P P++ W K+   I+K        +  +
Sbjct: 9022 PPTIKLRLSVRGDTIKVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEV 9081

Query: 895  RNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGEN 954
              SE  T + I KA R   G Y +           ++ +++ DRP PP+ + + D+  E+
Sbjct: 9082 SRSEAKTELSIPKAVREDKGTYTVTASNRLGSVFRNVHVEVYDRPSPPRNLAVTDIKAES 9141

Query: 955  VALTWTPPKDDGNAAITGYTIQKAD--KKSMEWFTVIEHYHRTSATITELVIGNEYYFRV 1012
              LTW  P D+G + IT Y I K D  +K  EW  V          I +L+   +Y FRV
Sbjct: 9142 CYLTWDAPLDNGGSEITHYVIDKRDASRKKAEWEEVTNTAVEKRYGIWKLIPNGQYEFRV 9201

Query: 1013 FSENMCGLSEDATMTKESAVIARD 1036
             + N  G+S++    K   V+ +D
Sbjct: 9202 RAVNKYGISDEC---KSDKVVIQD 9222



 Score =  209 bits (533), Expect = 9e-54
 Identities = 155/595 (26%), Positives = 276/595 (46%), Gaps = 28/595 (4%)

Query: 445   GQSSAKLSVDLKPLKILTPLTDQ-TVNLGKEICLKCEI-SENIPG-KWTKNGLPVQESDR 501
             G  +AK  V+L  + +     D   VN G+   L+ ++  + +P  +W +    ++ES R
Sbjct: 17240 GPITAKDEVELPRISMDPKFRDTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESAR 17299

Query: 502   LKVVHKGRIHKLVIANALTEDEGDYVFAPD--AYNVTLPAKVHVIDPPKIILDGLDADNT 559
              ++ +      L++ +A+  D G Y+      A + + P  V V+D P       +    
Sbjct: 17300 CEIKNTDFKALLIVKDAIRIDGGQYILRASNVAGSKSFPVNVKVLDRP----GPPEGPVQ 17355

Query: 560   VTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIR-----TESYPDSSTLVIDIA 614
             VT +   K  L    +  PP +   S     ++E     R       S   +++L +   
Sbjct: 17356 VTGVTSEKCSL----TWSPPLQDGGSDISHYVVEKRETSRLAWTVVASEVVTNSLKVTKL 17411

Query: 615   ERDDSGVYHINLKNE--AGEAHASIKVKVVD---FPDPPVAPTVTEVGDDWCIMNWEPPA 669
                +  V+ I   N+   GE   S  V + +    P PP +  VT +  D   + W  P 
Sbjct: 17412 LEGNEYVFRIMAVNKYGVGEPLESAPVLMKNPFVLPGPPKSLEVTNIAKDSMTVCWNRPD 17471

Query: 670   YDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISK 729
              DGGS I+GY +E++ +   RW++ N     +       + E   YE R+ A NA G+ +
Sbjct: 17472 SDGGSEIIGYIVEKRDRSGIRWIKCNKRRITDLRLRVTGLTEDHEYEFRVSAENAAGVGE 17531

Query: 730   PSMPS---RPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGT 786
             PS  +   +   P+    PPT   +   T  ++T+ W  P + G + + GYV+E C    
Sbjct: 17532 PSPATVYYKACDPVFKPGPPTNAHIVDTTKNSITLAWGKPIYDGGSEILGYVVEICKADE 17591

Query: 787   EDW-IVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPK 845
             E+W IV  +  +  T+F I+ L    +  +RV A+N  G  E       +  ++ +E P+
Sbjct: 17592 EEWQIVTPQTGLRVTRFEISKLTEHQEYKIRVCALNKVGLGEATSVPGTVKPEDKLEAPE 17651

Query: 846   IRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFI 905
             + +   L++  + R G +  + IPF+G+P PE+TW ++  E   +++ I      T + I
Sbjct: 17652 LDLDSELRKGIVVRAGGSARIHIPFKGRPTPEITWSREEGEFT-DKVQIEKGVNYTQLSI 17710

Query: 906   RKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDD 965
                +R+ +GKY L+++     ++A + ++++D PGPPQ + +++V  ++  L W PP  D
Sbjct: 17711 DNCDRNDAGKYILKLENSSGSKSAFVTVKVLDTPGPPQNLAVKEVRKDSAFLVWEPPIID 17770

Query: 966   GNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGL 1020
             G A +  Y I K +     +  V     +TS  +  L  G  YYFRV +EN  G+
Sbjct: 17771 GGAKVKNYVIDKRESTRKAYANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFGV 17825



 Score =  207 bits (528), Expect = 4e-53
 Identities = 124/404 (30%), Positives = 206/404 (50%), Gaps = 10/404 (2%)

Query: 645  PDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTF 704
            P PP A  V +V      + WEPP  DGG PI  Y IE+K++  +RW++       +  F
Sbjct: 7812 PGPPYALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKERLGTRWVKAGKTAGPDCNF 7871

Query: 705  EPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFV---PLAVTSPPTLLTVDSVTDTTVTM 761
                +IEG   + ++ A N  G+  PS P+       P +  SPP  L V       + +
Sbjct: 7872 RVTDVIEGTEVQFQVRAENEAGVGHPSEPTEILSIEDPTSPPSPPLDLHVTDAGRKHIAI 7931

Query: 762  RWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTIT-GLPTDAKIFVRVKAV 820
             W+PP+  G + + GY +E C  GTE W+  N   I   KF +  G+  D +  +RV+AV
Sbjct: 7932 AWKPPEKNGGSPIIGYHVEMCPVGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYVLRVRAV 7991

Query: 821  NAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTW 880
            NA G SEP   S+ ++ K+    P I +  H     I   GE +++ +PF+  P P ++W
Sbjct: 7992 NAIGVSEPSEISENVVAKDPDCKPTIDLETH---DIIVIEGEKLSIPVPFRAVPVPTVSW 8048

Query: 881  KKDGAEID-KNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRP 939
             KDG E+   +++ ++N      + + K+ R+ +G Y + ++      TASI++++I  P
Sbjct: 8049 HKDGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATASINVKVIGLP 8108

Query: 940  GPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATI 999
            GP + +K  D+   +  LTW PP+ DG   I  Y +++ +     +  V+   ++ S T+
Sbjct: 8109 GPCKDIKASDITKSSCKLTWEPPEFDGGTPILHYVLERREAGRRTYIPVMSGENKLSWTV 8168

Query: 1000 TELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNP 1043
             +L+   EY+FRV + N  G  E   +  ++ VIA+D K   +P
Sbjct: 8169 KDLIPNGEYFFRVKAVNKVGGGEYIEL--KNPVIAQDPKQPPDP 8210



 Score =  205 bits (522), Expect = 2e-52
 Identities = 140/501 (27%), Positives = 228/501 (45%), Gaps = 20/501 (3%)

Query: 543   VIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTES 602
             ++ PP++ LD +   + +TV  G  +R+   + G P P   W++  K ++      R + 
Sbjct: 11530 ILHPPEVELD-VTCRDVITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREK---RVDL 11585

Query: 603   YPDSSTLVIDIAE--RDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDW 660
               D   + + I E  R D G Y I+ KN +G A  S  V V+D P P     VT V  + 
Sbjct: 11586 IQDLPRVELQIKEAVRADHGKYIISAKNSSGHAQGSAIVNVLDRPGPCQNLKVTNVTKEN 11645

Query: 661   CIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIF 720
             C ++WE P  +GGS I  + +E +K     W  +  D+ K        ++    Y  R+ 
Sbjct: 11646 CTISWENPLDNGGSEITNFIVEYRKPNQKGWSIVASDVTKRLI--KANLLANNEYYFRVC 11703

Query: 721   AVNAIGISKPSMPSRPFV---PLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGY 777
             A N +G+        P +   P+     P  L +     T V ++WR PD+ G +    Y
Sbjct: 11704 AENKVGVGPTIETKTPILAINPIDRPGEPENLHIADKGKTFVYLKWRRPDYDGGSPNLSY 11763

Query: 778   VLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILV 837
              +E   +G++DW   +K  I +T + +     +     RV+  N  G S+    ++ ++V
Sbjct: 11764 HVERRLKGSDDWERVHKGSIKETHYMVDRCVENQIYEFRVQTKNEGGESD-WVKTEEVVV 11822

Query: 838   KEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQ---INI 894
             KE ++ P + +   L      + G+ + L    +GKP PE+ W KD    D  +   + I
Sbjct: 11823 KEDLQKPVLDLK--LSGVLTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKI 11880

Query: 895   RNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGEN 954
                   +   + KA+RS  GKY +          A   + ++D+PGP + +KI DV  + 
Sbjct: 11881 DTRADSSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATVNVLDKPGPVRNLKIVDVSSDR 11940

Query: 955   VALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFS 1014
               + W PP+DDG   I  Y ++K + K M W T          T+T L+ GNEY FRV +
Sbjct: 11941 CTVCWDPPEDDGGCEIQNYILEKCETKRMVWSTYSATVLTPGTTVTRLIEGNEYIFRVRA 12000

Query: 1015  ENMCGLSEDATMTKESAVIAR 1035
             EN  G       T+   VIA+
Sbjct: 12001 ENKIGTGPP---TESKPVIAK 12018



 Score =  204 bits (520), Expect = 3e-52
 Identities = 148/557 (26%), Positives = 258/557 (46%), Gaps = 31/557 (5%)

Query: 489   WTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAK----VHVI 544
             W K+G+ +++   +++        L + +A  +  G  V+  +A N +  AK    V V 
Sbjct: 21620 WFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRG--VYTVEAKNASGSAKAEIKVKVQ 21677

Query: 545   DPPKIILDGLDADNTVTVIAGNKLRL--EIPISGEPPP-------KAMWSRGDKAIMEGS 595
             D P  ++  +   N    I G K+ L  + P++    P       K   SR   A++E  
Sbjct: 21678 DTPGKVVGPIRFTN----ITGEKMTLWWDAPLNDGCAPITHYIIEKRETSRLAWALIED- 21732

Query: 596   GRIRTESYPDSSTLVIDIAERDDSGV--YHINLKNEAGEAHASIKVKVVDFPDPPVAPTV 653
              +   +SY     +  +  +   S V  + +    ++    A I+  V   PD P  P  
Sbjct: 21733 -KCEAQSYTAIKLINGNEYQFRVSAVNKFGVGRPLDSDPVVAQIQYTV---PDAPGIPEP 21788

Query: 654   TEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMR-LNFDLCKETTFEPKKMIEG 712
             + +  +   + W  P  DGGS I  Y +ER++K+S+RW++ ++     ET F+   + EG
Sbjct: 21789 SNITGNSITLTWARPESDGGSEIQQYILERREKKSTRWVKVISKRPISETRFKVTGLTEG 21848

Query: 713   VAYEVRIFAVNAIGISKPSMPSRPFV---PLAVTSPPTLLTVDSVTDTTVTMRWRPPDHI 769
               YE  + A NA G+   S  SR      P+    PPT++ V   + TTV++ W  P   
Sbjct: 21849 NEYEFHVMAENAAGVGPASGISRLIKCREPVNPPGPPTVVKVTDTSKTTVSLEWSKPVFD 21908

Query: 770   GAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPK 829
             G   + GY++E C     DW   N +   KT++T+T L    +   RV A+N AG  +  
Sbjct: 21909 GGMEIIGYIIEMCKADLGDWHKVNAEACVKTRYTVTDLQAGEEYKFRVSAINGAGKGDSC 21968

Query: 830   YYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDK 889
               +  I   + +  P++ I  + KQT++ R G ++ L I +QG+P P   W K  + +  
Sbjct: 21969 EVTGTIKAVDRLTAPELDIDANFKQTHVVRAGASIRLFIAYQGRPTPTAVWSKPDSNLSL 22028

Query: 890   NQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIED 949
              + +I  +++ + + +    R+ +GKY L V+ +   ++ +  ++++D PGPP  +  +D
Sbjct: 22029 -RADIHTTDSFSTLTVENCNRNDAGKYTLTVENNSGSKSITFTVKVLDTPGPPGPITFKD 22087

Query: 950   VWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYY 1009
             V   +  L W  P  DG A I  Y ++K +     W  + E   R    + +L  G  YY
Sbjct: 22088 VTRGSATLMWDAPLLDGGARIHHYVVEKREASRRSWQVISEKCTRQIFKVNDLAEGVPYY 22147

Query: 1010  FRVFSENMCGLSEDATM 1026
             FRV + N  G+ E   M
Sbjct: 22148 FRVSAVNEYGVGEPYEM 22164



 Score =  203 bits (517), Expect = 7e-52
 Identities = 137/482 (28%), Positives = 227/482 (47%), Gaps = 20/482 (4%)

Query: 645   PDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTF 704
             P  P  P V  V  +   + WE P +DGGS I+GY++E+K++ +  W++ N   C E  +
Sbjct: 22469 PSAPTRPEVYHVSANAMSIRWEEPYHDGGSKIIGYWVEKKERNTILWVKENKVPCLECNY 22528

Query: 705   EPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWR 764
             +   ++EG+ Y+ R +A+NA G+SK S  SRP +       P    V  VT +TV++ W 
Sbjct: 22529 KVTGLVEGLEYQFRTYALNAAGVSKASEASRPIMAQNPVDAPGRPEVTDVTRSTVSLIWS 22588

Query: 765   PPDHIGAAGLDGYVLE---YCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVN 821
              P + G + + GY++E       G   W+  N  ++    FT+T L        RV A N
Sbjct: 22589 APAYDGGSKVVGYIIERKPVSEVGDGRWLKCNYTIVSDNFFTVTALSEGDTYEFRVLAKN 22648

Query: 822   AAGA-SEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIR-RVGEAVNLVIPFQGKPRPELT 879
             AAG  S+    + P+  ++   PPK  +   L    +  R G  + L     GKP P++ 
Sbjct: 22649 AAGVISKGSESTGPVTCRDEYAPPKAELDARLHGDLVTIRAGSDLVLDAAVGGKPEPKII 22708

Query: 880   WKKDGAEIDK-NQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDR 938
             W K   E+D   +++++ +       I+  +RS SGKY L VK     +  S+ ++++D 
Sbjct: 22709 WTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSGKYTLTVKNASGTKAVSVMVKVLDS 22768

Query: 939   PGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSAT 998
             PGP   + +  V  E   L W+ P++DG A IT Y +++ +   + W  V       S  
Sbjct: 22769 PGPCGKLTVSRVTQEKCTLAWSLPQEDGGAEITHYIVERRETSRLNWVIVEGECPTLSYV 22828

Query: 999   ITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNP--VYEDFDFSEAPM- 1055
             +T L+  NEY FRV + N  G        +   ++AR+     +P  + E+    +  + 
Sbjct: 22829 VTRLIKNNEYIFRVRAVNKYG---PGVPVESEPIVARNSFTIPSPPGIPEEVGTGKEHII 22885

Query: 1056  --FTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMK-NKVAIVDDPRYRMFSNQGVCTLE 1112
               +T+P  +     G N   N  V    K  + W + NK  +V D R ++ S    C  +
Sbjct: 22886 IQWTKPESD-----GGNEISNYLVDKREKKSLRWTRVNKDYVVYDTRLKVTSLMEGCDYQ 22940

Query: 1113  IR 1114
              R
Sbjct: 22941 FR 22942



 Score =  200 bits (509), Expect = 6e-51
 Identities = 218/906 (24%), Positives = 364/906 (40%), Gaps = 113/906 (12%)

Query: 288  QVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEY 347
            +V +   V F  E+     + KW++N + I  S+KYI   K     L I +  + D + Y
Sbjct: 6278 RVKEQQEVVFNCEVNTEGAKAKWFRNEEAIFDSSKYIILQKDLVYTLRIRDAHLDDQANY 6337

Query: 348  YVTAGDE-----KCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKN 402
             V+  +      K +  L V E  + + + L+D      + V   C+V+  +  +KW KN
Sbjct: 6338 NVSLTNHRGENVKSAANLIVEEEDLRIVEPLKDIETMEKKSVTFWCKVNRLNVTLKWTKN 6397

Query: 403  GEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILT 462
            GEE+    +  YR  V+  KH+L I+     D  EY V     +S A+L +   P + + 
Sbjct: 6398 GEEVPFDNRVSYR--VDKYKHMLTIKDCGFPDEGEYIVTAGQDKSVAELLIIEAPTEFVE 6455

Query: 463  PLTDQTVNLGKEICLKCEIS-ENIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTE 521
             L DQTV    +    C++S E    KW +NG  ++E  + K    G IH+L+I +   +
Sbjct: 6456 HLEDQTVTEFDDAVFSCQLSREKANVKWYRNGREIKEGKKYKFEKDGSIHRLIIKDCRLD 6515

Query: 522  DEGDYVFAPD-----AYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISG 576
            DE +Y    +     A        V +I PP+ IL+   AD  V +   NK ++E+    
Sbjct: 6516 DECEYACGVEDRKSRARLFVEEIPVEIIRPPQDILEAPGAD-VVFLAELNKDKVEV---- 6570

Query: 577  EPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHAS 636
                   W R +  +++G               + DI  RD  G Y    K++  EA A 
Sbjct: 6571 ------QWLRNNMVVVQGDKHQMMSEGKIHRLQICDIKPRDQ-GEYRFIAKDK--EARAK 6621

Query: 637  IKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYF-IERKKKQSSRWMRLN 695
            +++          AP +     D  +        D G P+      +   K  + W + N
Sbjct: 6622 LELAA--------APKIKTADQDLVV--------DVGKPLTMVVPYDAYPKAEAEWFKEN 6665

Query: 696  FDL--------CKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPT 747
              L         ++T+F   +  +G     +I   N  G ++  +  +    + V  P  
Sbjct: 6666 EPLSTKTIDTTAEQTSFRILEAKKGDKGRYKIVLQNKHGKAEGFINLKV---IDVPGPVR 6722

Query: 748  LLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGL 807
             L V    D  V++ W  P   G + + GYV+E      + W++A  D  +  +FT+TGL
Sbjct: 6723 NLEVTETFDGEVSLAWEEPLTDGGSKIIGYVVERRDIKRKTWVLAT-DRAESCEFTVTGL 6781

Query: 808  PTDAKIFV-RVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNL 866
                  ++ RV A N  G  EP     P+  +   + P                G  +N+
Sbjct: 6782 QKGGVEYLFRVSARNRVGTGEPVETDNPVEARSKYDVP----------------GPPLNV 6825

Query: 867  VIPFQGKPRPELTWKKD----GAEIDKNQINIRNSET---DTIIFIRKAERS-------H 912
             I    +    LTW+      GAEI    I +R+  +   DT + +R  + S        
Sbjct: 6826 TITDVNRFGVSLTWEPPEYDGGAEITNYVIELRDKTSIRWDTAMTVRAEDLSATVTDVVE 6885

Query: 913  SGKYDLQVKVDKFV-----ETASIDIQI---IDRPGPPQIVKIEDVWGENVALTWTPPKD 964
              +Y  +V+    +       A+  +++   I+RP PP  +   D    +V L W PP  
Sbjct: 6886 GQEYSFRVRAQNRIGVGKPSAATPFVKVADPIERPSPPVNLTSSDQTQSSVQLKWEPPLK 6945

Query: 965  DGNAAITGYTIQKADKKSMEWFTV-IEHYHRTSATITELVIGNEYYFRVFSENMCGLSED 1023
            DG + I GY I++ ++    W    ++     +  +T L  GN+Y +RV +EN  G+S+ 
Sbjct: 6946 DGGSPILGYIIERCEEGKDNWIRCNMKLVPELTYKVTGLEKGNKYLYRVSAENKAGVSDP 7005

Query: 1024 ATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNA-TLNCSVRGNPK 1082
            + +                P+  D  F E  M      +   +   N  T+     G P+
Sbjct: 7006 SEIL--------------GPLTADDAFVEPTMDLSAFKDGLEVIVPNPITILVPSTGYPR 7051

Query: 1083 PKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLE 1142
            P  TW      +    R +M +      L I      D G Y  K  N + T+  E  ++
Sbjct: 7052 PTATWCFGDKVLETGDRVKMKTLSAYAELVISPSERSDKGIYTLKLENRVKTISGE--ID 7109

Query: 1143 VKVIAQ 1148
            V VIA+
Sbjct: 7110 VNVIAR 7115



 Score =  198 bits (503), Expect = 3e-50
 Identities = 173/674 (25%), Positives = 288/674 (42%), Gaps = 74/674 (10%)

Query: 398  KWFKNGEEIIP-----------GPKSRYRIRVEGKKHILIIEGATKA-------DAAEYS 439
            +W +  E ++P           G + ++R+R E    I     AT         DA +  
Sbjct: 8253 RWKRCNEHLVPILTYTAKGLEEGKEYQFRVRAENAAGISEPSRATPPTKAVDPIDAPKVI 8312

Query: 440  VMTT-----GGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKC---------EISENI 485
            + T+     G + +   S+   P   +T + D+ V + +EI  +          E+ E  
Sbjct: 8313 LRTSLEVKRGDEIALDASISGSPYPTITWIKDENVIVPEEIKKRAAPLVRRRKGEVQEEE 8372

Query: 486  PGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYN--VTLPAKVHV 543
            P       LP+ +   +    KG   +L + ++L  D G Y+   +  +     P  V V
Sbjct: 8373 PFV-----LPLTQRLSIDNSKKGE-SQLRVRDSLRPDHGLYMIKVENDHGIAKAPCTVSV 8426

Query: 544  IDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESY 603
            +D P   ++ +  D   T +             EPP       G   I+  +   + ++ 
Sbjct: 8427 LDTPGPPINFVFEDIRKTSVL---------CKWEPP----LDDGGSEIINYTLEKKDKTK 8473

Query: 604  PDSSTLVIDIAERD-----------DSGVYHINLKNEAGEAHASIKVKVVDF-----PDP 647
            PDS  +V+    R               ++ +  +N  G     +   +V       PD 
Sbjct: 8474 PDSEWIVVTSTLRHCKYSVTKLIEGKEYLFRVRAENRFGPGPPCVSKPLVAKDPFGPPDA 8533

Query: 648  PVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPK 707
            P  P V +V  +  ++ W  P  D GSPILGY++E+++  S+ W R+N  L         
Sbjct: 8534 PDKPIVEDVTSNSMLVKWNEPK-DNGSPILGYWLEKREVNSTHWSRVNKSLLNALKANVD 8592

Query: 708  KMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSP--PTLLTVDSVTDTTVTMRWRP 765
             ++EG+ Y  R+ A NA G  K S PS P       SP  P +  V   + TT+ + W P
Sbjct: 8593 GLLEGLTYVFRVCAENAAGPGKFSPPSDPKTAHDPISPPGPPIPRVTDTSSTTIELEWEP 8652

Query: 766  PDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGA 825
            P   G   + GY ++    GT +W    + +I   ++T+  +   A   +RV AVNAAG 
Sbjct: 8653 PAFNGGGEIVGYFVDKQLVGTNEWSRCTEKMIKVRQYTVKEIREGADYKLRVSAVNAAGE 8712

Query: 826  SEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGA 885
              P   +QP+ V E  EPP + +   +K       G+ + +     G+P P   W K+  
Sbjct: 8713 GPPG-ETQPVTVAEPQEPPAVELDVSVKGGIQIMAGKTLRIPAVVTGRPVPTKVWTKEEG 8771

Query: 886  EIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIV 945
            E+DK+++ I N  T + + I+ A R   G+Y +        + A+  +++ D PGP   +
Sbjct: 8772 ELDKDRVVIDNVGTKSELIIKDALRKDHGRYVITATNSCGSKFAAARVEVFDVPGPVLDL 8831

Query: 946  KIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIG 1005
            K      +   L W+ P+DDG + ITG+ I++ D K   W   IE   R+   IT L+ G
Sbjct: 8832 KPVVTNRKMCLLNWSDPEDDGGSEITGFIIERKDAKMHTWRQPIE-TERSKCDITGLLEG 8890

Query: 1006 NEYYFRVFSENMCG 1019
             EY FRV ++N  G
Sbjct: 8891 QEYKFRVIAKNKFG 8904



 Score =  192 bits (487), Expect = 2e-48
 Identities = 179/703 (25%), Positives = 312/703 (44%), Gaps = 63/703 (8%)

Query: 369   VTKQLEDTTAYCGERVELECE-VSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILII 427
             + K+++D T   GE  +L C+ V     ++KW++ G+E+I   K  Y++  +G+ H L +
Sbjct: 24163 IRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRK--YKMSSDGRTHTLTV 24220

Query: 428   EGATKADAAEYSVMTTGG----QSSAKLSVDLKP-LKILTPLTDQTVN-LGKEICLKCE- 480
                 + D   Y+ + T      ++S+KL +   P      PL ++    +G  + L    
Sbjct: 24221 MTEEQEDEGVYTCIATNEVGEVETSSKLLLQATPQFHPGYPLKEKYYGAVGSTLRLHVMY 24280

Query: 481   ISENIPGK-WTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPA 539
             I   +P   W      +Q S+ + + +      LV+ N   +           Y V L  
Sbjct: 24281 IGRPVPAMTWFHGQKLLQNSENITIENTEHYTHLVMKNVQRKTHAG------KYKVQLSN 24334

Query: 540   KVHVIDPPKIILDGLDADN----TVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIME-- 593
                 +D    ILD    D     T  ++    L+    IS +PP     S     ++E  
Sbjct: 24335 VFGTVDA---ILDVEIQDKPDKPTGPIVIEALLKNSAVISWKPPADDGGSWITNYVVEKC 24391

Query: 594   -----GSGRIRTESYPDSSTLVIDIAERDDSGVY-HINLKNEAG-----EAHASIKVKV- 641
                     ++ + +   ++  ++++ E  ++G Y  ++ +N  G     E  + + +K  
Sbjct: 24392 EAKEGAEWQLVSSAISVTTCRIVNLTE--NAGYYFRVSAQNTFGISDPLEVSSVVIIKSP 24449

Query: 642   VDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKE 701
              + P  P  PT+T V  D C++ W+PPA DGG+ I  Y++E+++K+ ++W+ +  +  +E
Sbjct: 24450 FEKPGAPGKPTITAVTKDSCVVAWKPPASDGGAKIRNYYLEKREKKQNKWISVTTEEIRE 24509

Query: 702   TTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTM 761
             T F  K +IEG+ YE R+   N  G S+ S  S P  P +          + + +  V  
Sbjct: 24510 TVFSVKNLIEGLEYEFRVKCENLGGESEWSEISEPITPKSDVPIQAPHFKEELRNLNVRY 24569

Query: 762   RWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTK-----FTITGLPTDAKIFVR 816
             +          G    ++++  +G E      K  I + K       I  +  D     +
Sbjct: 24570 QSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQLIIASVTDDDATVYQ 24629

Query: 817   VKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRV--GEAVNLVIPFQGKP 874
             V+A N  G+             E+  P KI +P+ L+         GE V++ IPF GKP
Sbjct: 24630 VRATNQGGSVSGT------ASLEVEVPAKIHLPKTLEGMGAVHALRGEVVSIKIPFSGKP 24683

Query: 875   RPELTWKKDGAEIDKN---QINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASI 931
              P +TW+K    ID N   Q+ +  S T +++F    ER  +G Y +  K    ++  ++
Sbjct: 24684 DPVITWQKGQDLIDNNGHYQVIVTRSFT-SLVFPNGVERKDAGFYVVCAKNRFGIDQKTV 24742

Query: 932   DIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEH 991
             ++ + D P PP+ VK+ DV  ++V LTWT P  DG + IT Y ++K    +  W  V   
Sbjct: 24743 ELDVADVPDPPRGVKVSDVSRDSVNLTWTEPASDGGSKITNYIVEKCATTAERWLRV-GQ 24801

Query: 992   YHRTSATITELVIGNEYYFRVFSENMCGLSE-----DATMTKE 1029
                T  T+  L     Y FRV +EN  GLS+     + T+TKE
Sbjct: 24802 ARETRYTVINLFGKTSYQFRVIAENKFGLSKPSEPSEPTITKE 24844



 Score =  181 bits (460), Expect = 3e-45
 Identities = 166/686 (24%), Positives = 284/686 (41%), Gaps = 75/686 (10%)

Query: 375  DTTAYCGERV-ELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKA 433
            D    CGE V E + EV+  +   KW+             YR++   +      +GA+K 
Sbjct: 7260 DKWVACGEPVAETKMEVTGLEEG-KWYA------------YRVKALNR------QGASKP 7300

Query: 434  DAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCEISENIPGK--WTK 491
                  +     Q + ++ +D+K L  LT      V  G +I L   ++     K  WTK
Sbjct: 7301 SRPTEEIQAVDTQEAPEIFLDVKLLAGLT------VKAGTKIELPATVTGKPEPKITWTK 7354

Query: 492  NGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNV----TLPAKVHVIDP- 546
              + +++  R+ + +  +   + I ++   D G Y+   +A NV    T   +V+V+D  
Sbjct: 7355 ADMILKQDKRITIENVPKKSTVTIVDSKRSDTGTYII--EAVNVCGRATAVVEVNVLDKP 7412

Query: 547  -PKIILDGLDADNTVTVIAGNKLR-------LEIPISGEPPPKAMWSRGDKAIMEGSGRI 598
             P    D  D  N   ++  N  R           +        +W +    + + + + 
Sbjct: 7413 GPPAAFDITDVTNESCLLTWNPPRDDGGSKITNYVVERRATDSEVWHKLSSTVKDTNFK- 7471

Query: 599  RTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGD 658
             T+  P+   +    AE     +Y +    +A    A  +    D P PP     +++  
Sbjct: 7472 ATKLIPNKEYIFRVAAE----NMYGVGEPVQASPITAKYQ---FDPPGPPTRLEPSDITK 7524

Query: 659  DWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVR 718
            D   + W  P  DGGSPI GY++ER    + +W+R N    K+TT+  K +     Y  R
Sbjct: 7525 DAVTLTWCEPDDDGGSPITGYWVERLDPDTDKWVRCNKMPVKDTTYRVKGLTNKKKYRFR 7584

Query: 719  IFAVNAIGISKPSMPSRPFV---PLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLD 775
            + A N  G  KPS  + P +   P+    PP   TV  V  T+V + W  P+H G A ++
Sbjct: 7585 VLAENLAGPGKPSKSTEPILIKDPIDPPWPPGKPTVKDVGKTSVRLNWTKPEHDGGAKIE 7644

Query: 776  GYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPI 835
             YV+E    GT++W+   +  +  T+  + GL    +   RV+AVN AG SEP   S P+
Sbjct: 7645 SYVIEMLKTGTDEWVRVAEG-VPTTQHLLPGLMEGQEYSFRVRAVNKAGESEPSEPSDPV 7703

Query: 836  LVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRP------------ELTWKKD 883
            L +E + PP    PR L+   I +    +   +P +    P               W+  
Sbjct: 7704 LCREKLYPPS--PPRWLEVINITKNTADLKWTVPEKDGGSPITNYIVEKRDVRRKGWQTV 7761

Query: 884  GAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQ 943
               +   +  +      ++   R A  +  G+ D        +E + +       PGPP 
Sbjct: 7762 DTTVKDTKCTVTPLTEGSLYVFRVAAENAIGQSDYTE-----IEDSVLAKDTFTTPGPPY 7816

Query: 944  IVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHY-HRTSATITEL 1002
             + + DV   +V L W PPK+DG   I  Y I+K ++    W    +      +  +T++
Sbjct: 7817 ALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKERLGTRWVKAGKTAGPDCNFRVTDV 7876

Query: 1003 VIGNEYYFRVFSENMCGLSEDATMTK 1028
            + G E  F+V +EN  G+   +  T+
Sbjct: 7877 IEGTEVQFQVRAENEAGVGHPSEPTE 7902



 Score =  162 bits (411), Expect = 1e-39
 Identities = 110/364 (30%), Positives = 175/364 (48%), Gaps = 16/364 (4%)

Query: 289  VDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYY 348
            V  G    F  EL+   + V+WY  G+++ PS K +   +G    L + + ++ D  E  
Sbjct: 5835 VTAGETATFDCELSYEDIPVEWYLKGKKLEPSDKVVPRSEGKVHTLTLRDVKLEDAGEVQ 5894

Query: 349  VTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIP 408
            +TA D K    LFV+EPP+  TK LED T   G    LECEVS ++A VKWFKNG EI+ 
Sbjct: 5895 LTAKDFKTHANLFVKEPPVEFTKPLEDQTVEEGATAVLECEVSRENAKVKWFKNGTEILK 5954

Query: 409  GPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQT 468
              K  Y I  +G+   L+I   T  D   Y+      ++S  L+V    ++ L PLTD  
Sbjct: 5955 SKK--YEIVADGRVRKLVIHDCTPEDIKTYTCDAKDFKTSCNLNVVPPHVEFLRPLTDLQ 6012

Query: 469  VNLGKEICLKCEIS-ENIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYV 527
            V   +    +CE+S EN   KW K+G  +++  +  ++ KG +  LVI   L +DE +Y 
Sbjct: 6013 VREKEMARFECELSRENAKVKWFKDGAEIKKGKKYDIISKGAVRILVINKCLLDDEAEY- 6071

Query: 528  FAPDAYNVTLPAKVHVIDPPKII---LDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMW 584
             + +         + V++   +    L  ++   T T+    KL  E+    +P  + +W
Sbjct: 6072 -SCEVRTARTSGMLTVLEEEAVFTKNLANIEVSETDTI----KLVCEV---SKPGAEVIW 6123

Query: 585  SRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDF 644
             +GD+ I+E +GR    +      LVI  A  +D+G Y+  L +   +    +     +F
Sbjct: 6124 YKGDEEIIE-TGRYEILTEGRKRILVIQNAHLEDAGNYNCRLPSSRTDGKVKVHELAAEF 6182

Query: 645  PDPP 648
               P
Sbjct: 6183 ISKP 6186



 Score =  157 bits (398), Expect = 4e-38
 Identities = 105/308 (34%), Positives = 159/308 (51%), Gaps = 19/308 (6%)

Query: 544   IDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESY 603
             +DPP+I +D    D T+ V AG   +++  I G+P P   W +GD+ +   + R+  +S 
Sbjct: 16166 VDPPRISMDPKYKD-TIVVHAGESFKVDADIYGKPIPTIQWIKGDQEL-SNTARLEIKST 16223

Query: 604   PDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTV-TEVGDDWCI 662
               +++L +  A R DSG Y +  KN AGE   ++ VKV+D P PP  P V + V  + C 
Sbjct: 16224 DFATSLSVKDAVRVDSGNYILKAKNVAGERSVTVNVKVLDRPGPPEGPVVISGVTAEKCT 16283

Query: 663   MNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDL----CKETTFEPKKMIEGVAYEVR 718
             + W+PP  DGGS I+ Y +ER++     W  ++ ++    CK T     K++EG  Y  R
Sbjct: 16284 LAWKPPLQDGGSDIINYIVERRETSRLVWTVVDANVQTLSCKVT-----KLLEGNEYTFR 16338

Query: 719   IFAVNAIGISKPSMPSRPFV---PLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLD 775
             I AVN  G+ +P + S P V   P  V   P    V +VT  ++ + W  P   G + + 
Sbjct: 16339 IMAVNKYGVGEP-LESEPVVAKNPFVVPDAPKAPEVTTVTKDSMIVVWERPASDGGSEIL 16397

Query: 776   GYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPI 835
             GYVLE   +    W   +K LI + +  +TGL  +     RV A NAAG SEP   S P 
Sbjct: 16398 GYVLEKRDKEGIRWTRCHKRLIGELRLRVTGLIENHDYEFRVSAENAAGLSEP---SPPS 16454

Query: 836   LVKEIIEP 843
               ++  +P
Sbjct: 16455 AYQKACDP 16462



 Score =  157 bits (398), Expect = 4e-38
 Identities = 101/319 (31%), Positives = 164/319 (51%), Gaps = 7/319 (2%)

Query: 531   DAYNVTLPAKV-HVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDK 589
             D   + LP  +   ++PP+I +    + +TV V AG+ L+++IPISG+P PK   SR D 
Sbjct: 20085 DPRELLLPVLIKEQLEPPEIDMKNFPS-HTVYVRAGSNLKVDIPISGKPLPKVTLSR-DG 20142

Query: 590   AIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPV 649
               ++ + R  TE   ++ T+ +  +   D+G Y I   N +G   A I + V+D P PP 
Sbjct: 20143 VPLKATMRFNTEITAENLTINLKESVTADAGRYEITAANSSGTTKAFINIVVLDRPGPPT 20202

Query: 650   APTV-TEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKK 708
              P V +++ ++   + WEPP YDGGS +  Y + +++  ++ W  ++  + + T  +  K
Sbjct: 20203 GPVVISDITEESVTLKWEPPKYDGGSQVTNYILLKRETSTAVWTEVSATVAR-TMMKVMK 20261

Query: 709   MIEGVAYEVRIFAVNAIGISK--PSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPP 766
             +  G  Y+ RI A N  GIS    S      +P     PP+   V +VT  ++T+ W  P
Sbjct: 20262 LTTGEEYQFRIKAENRFGISDHIDSACVTVKLPYTTPGPPSTPWVTNVTRESITVGWHEP 20321

Query: 767   DHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGAS 826
                G + + GY LE     +  W  ANK +I  T F +T +        RV A NAAG  
Sbjct: 20322 VSNGGSAVVGYHLEMKDRNSILWQKANKLVIRTTHFKVTTISAGLIYEFRVYAENAAGVG 20381

Query: 827   EPKYYSQPILVKEIIEPPK 845
             +P + S+P+L  +  EPP+
Sbjct: 20382 KPSHPSEPVLAIDACEPPR 20400



 Score =  157 bits (397), Expect = 5e-38
 Identities = 212/890 (23%), Positives = 342/890 (38%), Gaps = 93/890 (10%)

Query: 292  GGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTA 351
            G  V F+ EL   K+EV+W +N   +    K+    +G    L I + +  D  EY   A
Sbjct: 6554 GADVVFLAELNKDKVEVQWLRNNMVVVQGDKHQMMSEGKIHRLQICDIKPRDQGEYRFIA 6613

Query: 352  GDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSE-DDANVKWFKNGEEIIPGP 410
             D++   +L +   P + T   +D     G+ + +         A  +WFK  E     P
Sbjct: 6614 KDKEARAKLELAAAPKIKTAD-QDLVVDVGKPLTMVVPYDAYPKAEAEWFKENE-----P 6667

Query: 411  KSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLT--DQT 468
             S   I    ++    I  A K D   Y ++       A+  ++LK + +  P+   + T
Sbjct: 6668 LSTKTIDTTAEQTSFRILEAKKGDKGRYKIVLQNKHGKAEGFINLKVIDVPGPVRNLEVT 6727

Query: 469  VNLGKEICLKCEISENIPGKWTKN-GLPVQESD---RLKVVHKGRIHKLVIA-NALTEDE 523
                 E+ L  E  E +    +K  G  V+  D   +  V+   R          L +  
Sbjct: 6728 ETFDGEVSLAWE--EPLTDGGSKIIGYVVERRDIKRKTWVLATDRAESCEFTVTGLQKGG 6785

Query: 524  GDYVFAPDAYNVTLPAKVHVIDPP-----KIILDGLDADNTVTVIAGNKLRLEIPISGEP 578
             +Y+F   A N     +    D P     K  + G   + T+T +     R  + ++ EP
Sbjct: 6786 VEYLFRVSARNRVGTGEPVETDNPVEARSKYDVPGPPLNVTITDVN----RFGVSLTWEP 6841

Query: 579  PPKAMWSRGDKAIMEGSGRIR-------TESYPDSSTLVIDIAERDDSGVYHINLKNEAG 631
            P     +     ++E   +         T    D S  V D+ E  +   + +  +N  G
Sbjct: 6842 PEYDGGAEITNYVIELRDKTSIRWDTAMTVRAEDLSATVTDVVEGQEYS-FRVRAQNRIG 6900

Query: 632  EAHASIK---VKVVD---FPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKK 685
                S     VKV D    P PPV  T ++       + WEPP  DGGSPILGY IER +
Sbjct: 6901 VGKPSAATPFVKVADPIERPSPPVNLTSSDQTQSSVQLKWEPPLKDGGSPILGYIIERCE 6960

Query: 686  KQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGIS----------------K 729
            +    W+R N  L  E T++   + +G  Y  R+ A N  G+S                +
Sbjct: 6961 EGKDNWIRCNMKLVPELTYKVTGLEKGNKYLYRVSAENKAGVSDPSEILGPLTADDAFVE 7020

Query: 730  PSMPSRPF---VPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGT 786
            P+M    F   + + V +P T+L V S      T  W   D +   G    V        
Sbjct: 7021 PTMDLSAFKDGLEVIVPNPITIL-VPSTGYPRPTATWCFGDKVLETG--DRVKMKTLSAY 7077

Query: 787  EDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKI 846
             + +++  +  DK  +T+       K+  RVK ++  G  +    ++P   KE+      
Sbjct: 7078 AELVISPSERSDKGIYTL-------KLENRVKTIS--GEIDVNVIARPSAPKELKFGDIT 7128

Query: 847  RIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIR 906
            +   HL        G +       + +     TW K    +   +  + +         +
Sbjct: 7129 KDSVHLTWEPPDDDGGSPLTGYVVEKREVSRKTWTKVMDFVTDLEFTVPDLVQGKEYLFK 7188

Query: 907  KAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDG 966
               R+  G  +    VD+ V  ++        P PP+ VK  D    ++ LTW PPK+DG
Sbjct: 7189 VCARNKCGPGE-PAYVDEPVNMSTPATV----PDPPENVKWRDRTANSIFLTWDPPKNDG 7243

Query: 967  NAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATM 1026
             + I GY +++  + S +W    E    T   +T L  G  Y +RV + N  G S+ +  
Sbjct: 7244 GSRIKGYIVERCPRGSDKWVACGEPVAETKMEVTGLEEGKWYAYRVKALNRQGASKPSRP 7303

Query: 1027 TKESAVIARDGKIYKNPVYEDFDFSEAP---MFTQPLVNTYAIAGYNATLNCSVRGNPKP 1083
            T+E   +               D  EAP   +  + L      AG    L  +V G P+P
Sbjct: 7304 TEEIQAV---------------DTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEP 7348

Query: 1084 KITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLG 1133
            KITW K  + +  D R  + +     T+ I      D GTY  +AVN  G
Sbjct: 7349 KITWTKADMILKQDKRITIENVPKKSTVTIVDSKRSDTGTYIIEAVNVCG 7398



 Score =  157 bits (397), Expect = 5e-38
 Identities = 146/550 (26%), Positives = 232/550 (42%), Gaps = 42/550 (7%)

Query: 385   ELEC-EVSEDDANVKWFK----NGEEII-----------PGPKSRYRIRVEGKKHILIIE 428
             ELE   +S+D   ++W K     G+EI+              K   + R++ K+    I 
Sbjct: 24064 ELEILSISKDSVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERIKDKQ--FTIG 24121

Query: 429   GATKADAAEYSVMT---TGGQSSAKLSVDLKPLK-------ILTPLTDQTVNLGKEICLK 478
             G  +A   E+ V     TG     + ++ +K          I   + D T  LG+   L 
Sbjct: 24122 GLLEATEYEFRVFAENETGLSRPRRTAMSIKTKLTSGEAPGIRKEMKDVTTKLGEAAQLS 24181

Query: 479   CEI-SENIPG-KWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDY--VFAPDAYN 534
             C+I    +P  KW + G  + +S + K+   GR H L +     EDEG Y  +   +   
Sbjct: 24182 CQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVGE 24241

Query: 535   VTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEG 594
             V   +K+ +   P+    G           G+ LRL +   G P P   W  G K +++ 
Sbjct: 24242 VETSSKLLLQATPQFH-PGYPLKEKYYGAVGSTLRLHVMYIGRPVPAMTWFHGQK-LLQN 24299

Query: 595   SGRIRTESYPDSSTLVI-DIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTV 653
             S  I  E+    + LV+ ++  +  +G Y + L N  G   A + V++ D PD P  P V
Sbjct: 24300 SENITIENTEHYTHLVMKNVQRKTHAGKYKVQLSNVFGTVDAILDVEIQDKPDKPTGPIV 24359

Query: 654   TE-VGDDWCIMNWEPPAYDGGSPILGYFIER-KKKQSSRWMRLNFDLCKETTFEPKKMIE 711
              E +  +  +++W+PPA DGGS I  Y +E+ + K+ + W  ++  +   TT     + E
Sbjct: 24360 IEALLKNSAVISWKPPADDGGSWITNYVVEKCEAKEGAEWQLVSSAI-SVTTCRIVNLTE 24418

Query: 712   GVAYEVRIFAVNAIGISKPSMPSRPFV---PLAVTSPPTLLTVDSVTDTTVTMRWRPPDH 768
                Y  R+ A N  GIS P   S   +   P      P   T+ +VT  +  + W+PP  
Sbjct: 24419 NAGYYFRVSAQNTFGISDPLEVSSVVIIKSPFEKPGAPGKPTITAVTKDSCVVAWKPPAS 24478

Query: 769   IGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEP 828
              G A +  Y LE   +    WI    + I +T F++  L    +   RVK  N  G SE 
Sbjct: 24479 DGGAKIRNYYLEKREKKQNKWISVTTEEIRETVFSVKNLIEGLEYEFRVKCENLGGESEW 24538

Query: 829   KYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEID 888
                S+PI  K  +          L+   +R    A  LV    G P+P + W + G EI 
Sbjct: 24539 SEISEPITPKSDVPIQAPHFKEELRNLNVRYQSNA-TLVCKVTGHPKPIVKWYRQGKEII 24597

Query: 889   KNQINIRNSE 898
              + +  R  E
Sbjct: 24598 ADGLKYRIQE 24607



 Score =  156 bits (395), Expect = 9e-38
 Identities = 103/340 (30%), Positives = 163/340 (47%), Gaps = 15/340 (4%)

Query: 516   ANALTEDEGDYVFAPDAYNVT---LPAKVHVIDPPKIILDGLDA----DNTVTVIAGNKL 568
             A  LTE + +Y F   A N      P+++ V+    ++   LD     D        +  
Sbjct: 13570 AKDLTEGK-EYTFRVSAENENGEGTPSEITVVARDDVVAPDLDLKGLPDLCYLAKENSNF 13628

Query: 569   RLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKN 628
             RL+IPI G+P P   W +G+  +   + R+  ES   ++TL++   ++ D+G Y I LKN
Sbjct: 13629 RLKIPIKGKPAPSVSWKKGEDPLATDT-RVSVESSAVNTTLIVYDCQKSDAGKYTITLKN 13687

Query: 629   EAGEAHASIKVKVVDFPDPPVAPT-VTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQ 687
              AG    +I +KVV  P  P  P    EV  +   + W PP  DGGS I  Y +E++   
Sbjct: 13688 VAGTKEGTISIKVVGKPGIPTGPIKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDSV 13747

Query: 688   SSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFV---PLAVTS 744
             +++W+       ++TTF   ++ EG+ Y  R+ A N  G+ +  + S P V   P  V  
Sbjct: 13748 NNKWVTCA-SAVQKTTFRVTRLHEGMEYTFRVSAENKYGVGE-GLKSEPIVARHPFDVPD 13805

Query: 745   PPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTI 804
              P    +  V   +V++ W  P   G + + GY LE+    +  W  ANK  I    F +
Sbjct: 13806 APPPPNIVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTPIRMRDFKV 13865

Query: 805   TGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPP 844
             TGL    +   RV A+N AG  +P   S+P++  + I+PP
Sbjct: 13866 TGLTEGLEYEFRVMAINLAGVGKPSLPSEPVVALDPIDPP 13905



 Score =  155 bits (391), Expect = 3e-37
 Identities = 98/310 (31%), Positives = 156/310 (50%), Gaps = 8/310 (2%)

Query: 547   PKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDS 606
             P++ L G+     V   AG+ +++EIP+ G P P   W +GD+ I++ + R+  E+   S
Sbjct: 14691 PELDLRGI-YQKLVIAKAGDNIKVEIPVLGRPKPTVTWKKGDQ-ILKQTQRVNFETTATS 14748

Query: 607   STLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPT-VTEVGDDWCIMNW 665
             + L I+   R DSG Y +  +N  GE    I ++V D P PP  P    EV  D+   +W
Sbjct: 14749 TILNINECVRSDSGPYPLTARNIVGEVGDVITIQVHDIPGPPTGPIKFDEVSSDFVTFSW 14808

Query: 666   EPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAI 725
             +PP  DGG PI  Y +E ++  S+ W+ L   + + TT++  ++  G+ Y+ R+ A N  
Sbjct: 14809 DPPENDGGVPISNYVVEMRQTDSTTWVELATTVIR-TTYKATRLTTGLEYQFRVKAQNRY 14867

Query: 726   GISKPSMPSRPFV---PLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYC 782
             G+  P + S   V   P  V  PP    V +VT  ++T+ W  P   G + + GY +E  
Sbjct: 14868 GVG-PGITSACIVANYPFKVPGPPGTPQVTAVTKDSMTISWHEPLSDGGSPILGYHVERK 14926

Query: 783   FEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIE 842
                   W   +K L+    F  +GL        RV A N AG S+P   S+P+L  + I+
Sbjct: 14927 ERNGILWQTVSKALVPGNIFKSSGLTDGIAYEFRVIAENMAGKSKPSKPSEPMLALDPID 14986

Query: 843   PPKIRIPRHL 852
             PP   +P ++
Sbjct: 14987 PPGKPVPLNI 14996



 Score =  154 bits (389), Expect = 5e-37
 Identities = 103/318 (32%), Positives = 157/318 (49%), Gaps = 10/318 (3%)

Query: 530   PDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDK 589
             P   +V + AK  VI P   +L      NT TV+AG  L++++P  G P P   W + D 
Sbjct: 15760 PRQLSVPVIAKDLVIPPAFKLLF-----NTFTVLAGEDLKVDVPFIGRPTPAVTWHK-DN 15813

Query: 590   AIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPV 649
               ++ + R+  ES  ++S L I  A R+D G Y + L N AGEA  ++ V V+D P PP 
Sbjct: 15814 VPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAGEAIETLNVIVLDKPGPPT 15873

Query: 650   APT-VTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKK 708
              P  + EV  D   ++W PP YDGGS I  Y +E++   ++ W  ++  + + TT +  +
Sbjct: 15874 GPVKMDEVTADSITLSWGPPKYDGGSSINNYIVEKRDTSTTTWQIVSATVAR-TTIKACR 15932

Query: 709   MIEGVAYEVRIFAVNAIGISK--PSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPP 766
             +  G  Y+ RI A N  G S    S P+    P  V  PP    V   +  ++ ++W  P
Sbjct: 15933 LKTGCEYQFRIAAENRYGKSTYLNSEPTVAQYPFKVPGPPGTPVVTLSSRDSMEVQWNEP 15992

Query: 767   DHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGAS 826
                G + + GY LE     +  W+  NK  I +TKF  TGL    +   RV A N  G  
Sbjct: 15993 ISDGGSRVIGYHLERKERNSILWVKLNKTPIPQTKFKTTGLEEGVEYEFRVSAENIVGIG 16052

Query: 827   EPKYYSQPILVKEIIEPP 844
             +P   S+  + ++  +PP
Sbjct: 16053 KPSKVSECYVARDPCDPP 16070



 Score =  149 bits (375), Expect = 2e-35
 Identities = 97/304 (31%), Positives = 142/304 (46%), Gaps = 5/304 (1%)

Query: 544   IDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESY 603
             ID P   LD    D  + V AG    LE  I G+P P  +WS+  K + E + R+  +S 
Sbjct: 18330 IDAPNASLDPKYKD-VIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKST 18388

Query: 604   PDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPT-VTEVGDDWCI 662
                +TLV+    R D G Y + L N  G     I VKV+D P PP  P  VT V  + C 
Sbjct: 18389 IQKTTLVVKDCIRTDGGQYILKLSNVGGTKSIPITVKVLDRPGPPEGPLKVTGVTAEKCY 18448

Query: 663   MNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAV 722
             + W PP  DGG+ I  Y IE+++     W +++ ++ +   ++  K++ G  Y  R+ AV
Sbjct: 18449 LAWNPPLQDGGANISHYIIEKRETSRLSWTQVSTEV-QALNYKVTKLLPGNEYIFRVMAV 18507

Query: 723   NAIGISKP--SMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLE 780
             N  GI +P  S P     P     PP+   V ++T  ++ + W  P   G   ++GY+LE
Sbjct: 18508 NKYGIGEPLESGPVTACNPYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILE 18567

Query: 781   YCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEI 840
                +    W   NK  +   +  +TGL        RV A NAAG  EP   S      + 
Sbjct: 18568 KRDKEGVRWTKCNKKTLTDLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRACDA 18627

Query: 841   IEPP 844
             + PP
Sbjct: 18628 LYPP 18631



 Score =  146 bits (369), Expect = 1e-34
 Identities = 189/864 (21%), Positives = 334/864 (38%), Gaps = 120/864 (13%)

Query: 297  FVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKC 356
            F VEL+   + VKW+KN Q +  +     + +G    +   +  + D S+  V A     
Sbjct: 5576 FTVELSHDNIRVKWFKNDQRLHTTRSVSMQDEGKTHSITFKDLSIDDTSQIRVEAMGMSS 5635

Query: 357  STELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRI 416
              +L V E     T +L+D T    + V L+CE+S+ DA VKWFK+G+EI P   +   I
Sbjct: 5636 EAKLTVLEGDPYFTGKLQDYTGVEKDEVILQCEISKADAPVKWFKDGKEIKPSKNA--VI 5693

Query: 417  RVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEIC 476
            + +GKK +LI++ A K+D  +Y+      ++S KL ++ + +K++ PL    V   +   
Sbjct: 5694 KADGKKRMLILKKALKSDIGQYTCDCGTDKTSGKLDIEDREIKLVRPLHSVEVMETETAR 5753

Query: 477  LKCEISE-NIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNV 535
             + EISE +I   W   G  + ++   ++  +G+IH LV+ N   +  G   F   A NV
Sbjct: 5754 FETEISEDDIHANWKLKGEALLQTPDCEIKEEGKIHSLVLHNCRLDQTGGVDF--QAANV 5811

Query: 536  TLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGS 595
               A + V   P++I   L     VTV AG     +  +S E  P   + +G K  +E S
Sbjct: 5812 KSSAHLRV--KPRVI-GLLRPLKDVTVTAGETATFDCELSYEDIPVEWYLKGKK--LEPS 5866

Query: 596  GRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTE 655
             ++   S     TL +   + +D+G   +  K+    A+  +K   V+F  P    TV E
Sbjct: 5867 DKVVPRSEGKVHTLTLRDVKLEDAGEVQLTAKDFKTHANLFVKEPPVEFTKPLEDQTVEE 5926

Query: 656  VGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFE------PKKM 709
                            G + +L   + R+  +  +W +   ++ K   +E       +K+
Sbjct: 5927 ----------------GATAVLECEVSRENAK-VKWFKNGTEILKSKKYEIVADGRVRKL 5969

Query: 710  I--EGVAYEVRIFAVNA--------IGISKPSMP-SRPFVPLAVTSPPTLLTVDSVTDTT 758
            +  +    +++ +  +A        + +  P +   RP   L V           ++   
Sbjct: 5970 VIHDCTPEDIKTYTCDAKDFKTSCNLNVVPPHVEFLRPLTDLQVREKEMARFECELSREN 6029

Query: 759  VTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVK 818
              ++W      GA    G   +   +G    +V NK L+D           +A+    V+
Sbjct: 6030 AKVKWFKD---GAEIKKGKKYDIISKGAVRILVINKCLLD----------DEAEYSCEVR 6076

Query: 819  AVNAAG----ASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKP 874
                +G      E   +++ +   E+ E   I++   +                    KP
Sbjct: 6077 TARTSGMLTVLEEEAVFTKNLANIEVSETDTIKLVCEV-------------------SKP 6117

Query: 875  RPELTWKKDGAE-IDKNQINIRNSETDTIIFIRKAERSHSGKYDLQV---KVDKFVETAS 930
              E+ W K   E I+  +  I       I+ I+ A    +G Y+ ++   + D  V+   
Sbjct: 6118 GAEVIWYKGDEEIIETGRYEILTEGRKRILVIQNAHLEDAGNYNCRLPSSRTDGKVKVHE 6177

Query: 931  IDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQ-KADKKSMEWFTVI 989
            +  + I +P   +I++     GE      +  K+        + +Q K D K++E     
Sbjct: 6178 LAAEFISKPQNLEILE-----GEKAEFVCSISKE-------SFPVQWKRDDKTLE----- 6220

Query: 990  EHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFD 1049
                           G++Y      +    + +DAT+      +   G            
Sbjct: 6221 --------------SGDKYDVIADGKKRVLVVKDATLQDMGTYVVMVGAA---RAAAHLT 6263

Query: 1050 FSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVC 1109
              E      PL +T          NC V      K  W +N+ AI D  +Y +     V 
Sbjct: 6264 VIEKLRIVVPLKDTRVKEQQEVVFNCEV-NTEGAKAKWFRNEEAIFDSSKYIILQKDLVY 6322

Query: 1110 TLEIRKPSPYDGGTYCCKAVNDLG 1133
            TL IR     D   Y     N  G
Sbjct: 6323 TLRIRDAHLDDQANYNVSLTNHRG 6346



 Score =  146 bits (369), Expect = 1e-34
 Identities = 96/339 (28%), Positives = 169/339 (49%), Gaps = 21/339 (6%)

Query: 521   EDEGDYVF---APDAYNVTLPAK----VHVID---PPKIILDGLDADNTVTVIAGNKLRL 570
             E++  Y F   A  A N++ P++    V ++    PP+I L  +   + +TV AG  + L
Sbjct: 12885 EEKAQYQFRAIARTAVNISPPSEPSDPVTILAENVPPRIDLS-VAMKSLLTVKAGTNVCL 12943

Query: 571   EIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEA 630
             +  + G+P P   W + D  +++ +  I+     +  TL +    R DSG Y I  +N +
Sbjct: 12944 DATVFGKPMPTVSWKK-DGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTITAENSS 13002

Query: 631   GEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSR 690
             G   A+IK+KV+D P PP +  + ++  D  +++WEPP  DGGS I  Y +++++     
Sbjct: 13003 GSKSATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYIVDKRETSRPN 13062

Query: 691   WMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGI-----SKPSMPSRPFVPLAVTSP 745
             W +++  +   T+   +K+IEG  Y+ RI A N  G+     ++P++   P+ P     P
Sbjct: 13063 WAQVSATV-PITSCSVEKLIEGHEYQFRICAENKYGVGDPVFTEPAIAKNPYDPPGRCDP 13121

Query: 746   PTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTIT 805
             P    + ++T   +T+ W+PP   G + + GY+LE       +W   N+  I +     T
Sbjct: 13122 P---VISNITKDHMTVSWKPPADDGGSPITGYLLEKRETQAVNWTKVNRKPIIERTLKAT 13178

Query: 806   GLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPP 844
             GL    +   RV A+N AG  +P   S+    ++   PP
Sbjct: 13179 GLQEGTEYEFRVTAINKAGPGKPSDASKAAYARDPQYPP 13217



 Score =  145 bits (365), Expect = 3e-34
 Identities = 110/374 (29%), Positives = 173/374 (46%), Gaps = 19/374 (5%)

Query: 288  QVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEY 347
            QV +    RF  EL+    +VKW+K+G EI+   KY    KG  RIL IN C + D++EY
Sbjct: 6012 QVREKEMARFECELSRENAKVKWFKDGAEIKKGKKYDIISKGAVRILVINKCLLDDEAEY 6071

Query: 348  YVTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEII 407
                   + S  L V E   + TK L +      + ++L CEVS+  A V W+K  EEII
Sbjct: 6072 SCEVRTARTSGMLTVLEEEAVFTKNLANIEVSETDTIKLVCEVSKPGAEVIWYKGDEEII 6131

Query: 408  PGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQ 467
                 RY I  EG+K IL+I+ A   DA  Y+      ++  K+ V     + ++   + 
Sbjct: 6132 --ETGRYEILTEGRKRILVIQNAHLEDAGNYNCRLPSSRTDGKVKVHELAAEFISKPQNL 6189

Query: 468  TVNLGKEICLKCEIS-ENIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDY 526
             +  G++    C IS E+ P +W ++   ++  D+  V+  G+   LV+ +A  +D G Y
Sbjct: 6190 EILEGEKAEFVCSISKESFPVQWKRDDKTLESGDKYDVIADGKKRVLVVKDATLQDMGTY 6249

Query: 527  VF----APDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKA 582
            V     A  A ++T+  K+ ++ P K        D  V          E+   G    KA
Sbjct: 6250 VVMVGAARAAAHLTVIEKLRIVVPLK--------DTRVKEQQEVVFNCEVNTEG---AKA 6298

Query: 583  MWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVV 642
             W R ++AI + S  I  +      TL I  A  DD   Y+++L N  GE   S    +V
Sbjct: 6299 KWFRNEEAIFDSSKYIILQK-DLVYTLRIRDAHLDDQANYNVSLTNHRGENVKSAANLIV 6357

Query: 643  DFPDPPVAPTVTEV 656
            +  D  +   + ++
Sbjct: 6358 EEEDLRIVEPLKDI 6371



 Score =  144 bits (362), Expect = 6e-34
 Identities = 89/302 (29%), Positives = 150/302 (49%), Gaps = 8/302 (2%)

Query: 547   PKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDS 606
             P   L G+  +  +T  AG+   +++PISG P PK  W   +  + E + R+   +  D 
Sbjct: 22273 PTADLTGI-TNQLITCKAGSPFTIDVPISGRPAPKVTWKLEEMRLKE-TDRVSITTTKDR 22330

Query: 607   STLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPT-VTEVGDDWCIMNW 665
             +TL +  + R DSG Y + L+N AG    S+ V V+  P P   P  V+ V  + C+++W
Sbjct: 22331 TTLTVKDSMRGDSGRYFLTLENTAGVKTFSVTVVVIGRPGPVTGPIEVSSVSAESCVLSW 22390

Query: 666   EPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAI 725
               P   GG+ I  Y +E+++  ++ W  +N  + K T  +   + + + Y  R+ + N  
Sbjct: 22391 GEPKDGGGTEITNYIVEKRESGTTAWQLVNSSV-KRTQIKVTHLTKYMEYSFRVSSENRF 22449

Query: 726   GISKPSMPSRPFV---PLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYC 782
             G+SKP + S P +   P    S PT   V  V+   +++RW  P H G + + GY +E  
Sbjct: 22450 GVSKP-LESAPIIAEHPFVPPSAPTRPEVYHVSANAMSIRWEEPYHDGGSKIIGYWVEKK 22508

Query: 783   FEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIE 842
                T  W+  NK    +  + +TGL    +   R  A+NAAG S+    S+PI+ +  ++
Sbjct: 22509 ERNTILWVKENKVPCLECNYKVTGLVEGLEYQFRTYALNAAGVSKASEASRPIMAQNPVD 22568

Query: 843   PP 844
              P
Sbjct: 22569 AP 22570



 Score =  142 bits (359), Expect = 1e-33
 Identities = 133/536 (24%), Positives = 207/536 (38%), Gaps = 70/536 (13%)

Query: 642  VDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKE 701
            +D P PP  PTV +VG     +NW  P +DGG+ I  Y IE  K  +  W+R+   +   
Sbjct: 7609 IDPPWPPGKPTVKDVGKTSVRLNWTKPEHDGGAKIESYVIEMLKTGTDEWVRVAEGVPTT 7668

Query: 702  TTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFV---PLAVTSPPTLLTVDSVTDTT 758
                P  M EG  Y  R+ AVN  G S+PS PS P +    L   SPP  L V ++T  T
Sbjct: 7669 QHLLPGLM-EGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLEVINITKNT 7727

Query: 759  VTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVK 818
              ++W  P+  G + +  Y++E      + W   +  + D TK T+T L   +    RV 
Sbjct: 7728 ADLKWTVPEKDGGSPITNYIVEKRDVRRKGWQTVDTTVKD-TKCTVTPLTEGSLYVFRVA 7786

Query: 819  AVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPEL 878
            A NA G S+       +L K+    P                G    L +    K   +L
Sbjct: 7787 AENAIGQSDYTEIEDSVLAKDTFTTP----------------GPPYALAVVDVTKRHVDL 7830

Query: 879  TW---KKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQI 935
             W   K DG    +  +  +     T    R  +   +   D   +V   +E   +  Q+
Sbjct: 7831 KWEPPKNDGGRPIQRYVIEKKERLGT----RWVKAGKTAGPDCNFRVTDVIEGTEVQFQV 7886

Query: 936  -----------------------IDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITG 972
                                      P PP  + + D   +++A+ W PP+ +G + I G
Sbjct: 7887 RAENEAGVGHPSEPTEILSIEDPTSPPSPPLDLHVTDAGRKHIAIAWKPPEKNGGSPIIG 7946

Query: 973  YTIQKADKKSMEWFTVIEHYHRTSATITE--LVIGNEYYFRVFSENMCGLSEDATMTKES 1030
            Y ++     + +W  V     +      E  +V   EY  RV + N  G+SE + +++  
Sbjct: 7947 YHVEMCPVGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAIGVSEPSEISEN- 8005

Query: 1031 AVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKN 1090
             V+A+D         E  D                I G   ++    R  P P ++W K+
Sbjct: 8006 -VVAKDPDCKPTIDLETHDI-------------IVIEGEKLSIPVPFRAVPVPTVSWHKD 8051

Query: 1091 KVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVKVI 1146
               +    R  M ++     LE+ K    D G Y     N LG+      + VKVI
Sbjct: 8052 GKEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSA--TASINVKVI 8105



 Score =  140 bits (352), Expect = 9e-33
 Identities = 91/298 (30%), Positives = 146/298 (48%), Gaps = 7/298 (2%)

Query: 546   PPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPD 605
             PPK  LD     + VT+ AG+ L L+  + G+P PK +W++GDK  ++   ++  +    
Sbjct: 22671 PPKAELDARLHGDLVTIRAGSDLVLDAAVGGKPEPKIIWTKGDKE-LDLCEKVSLQYTGK 22729

Query: 606   SSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNW 665
              +T VI   +R DSG Y + +KN +G    S+ VKV+D P P    TV+ V  + C + W
Sbjct: 22730 RATAVIKFCDRSDSGKYTLTVKNASGTKAVSVMVKVLDSPGPCGKLTVSRVTQEKCTLAW 22789

Query: 666   EPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAI 725
               P  DGG+ I  Y +ER++     W+ +  + C   ++   ++I+   Y  R+ AVN  
Sbjct: 22790 SLPQEDGGAEITHYIVERRETSRLNWVIVEGE-CPTLSYVVTRLIKNNEYIFRVRAVNKY 22848

Query: 726   GISKPSMPSRPFV---PLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYC 782
             G   P + S P V      + SPP +          + ++W  P+  G   +  Y+++  
Sbjct: 22849 GPGVP-VESEPIVARNSFTIPSPPGIPEEVGTGKEHIIIQWTKPESDGGNEISNYLVDKR 22907

Query: 783   FEGTEDWIVANKD-LIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKE 839
              + +  W   NKD ++  T+  +T L        RV AVNAAG SEP   S  I  +E
Sbjct: 22908 EKKSLRWTRVNKDYVVYDTRLKVTSLMEGCDYQFRVTAVNAAGNSEPSEASNFISCRE 22965



 Score =  139 bits (350), Expect = 2e-32
 Identities = 112/414 (27%), Positives = 188/414 (45%), Gaps = 21/414 (5%)

Query: 295  VRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDE 354
            + F V +    +  KW KNG EI+ + K     K     L I N    D ++Y   AG  
Sbjct: 2940 ITFEVTVNYEGISYKWLKNGVEIKSTDKCQMRTKKLTHSLNIRNVHFGDAADYTFVAGKA 2999

Query: 355  KCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRY 414
              +  L+V    I   K ++D      +R   ECEVSE D  V+W K+ +E+      R 
Sbjct: 3000 TSTATLYVEARHIEFRKHIKDIKVLEKKRAMFECEVSEPDITVQWMKDDQEL--QITDRI 3057

Query: 415  RIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKE 474
            +I+ E   H L+I     +DA +Y+V+  G  S+AKL V+ + ++I +   +  V   + 
Sbjct: 3058 KIQKEKYVHRLLIPSTRMSDAGKYTVVAGGNVSTAKLFVEGRDVRIRSIKKEVQVIEKQR 3117

Query: 475  ICLKCEISE-NIPGKWTKNGLPV--QESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPD 531
              ++ E++E ++   W K+G+ +  Q  +R K V + RIH++ I+     D G+Y F   
Sbjct: 3118 AVVEFEVNEDDVDAHWYKDGIEINFQVQERHKYVVERRIHRMFISETRQSDAGEYTFVAG 3177

Query: 532  AYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAI 591
                ++   V+  +PP++    L     VTV +G   R    ISG P PK  W + ++ +
Sbjct: 3178 RNRSSVTLYVNAPEPPQV----LQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLL 3233

Query: 592  MEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAG----EAHASIKVKVVDFPD- 646
              G  + +        TL++  A  +D+ VY    KN+ G     A  S++V  V  PD 
Sbjct: 3234 STGF-KCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQ 3292

Query: 647  --PPVAPTVTEVGDDWCIMNWEPPAY----DGGSPILGYFIERKKKQSSRWMRL 694
              P   P +     D      +P  +     G    + ++ + KK + SR+ R+
Sbjct: 3293 EMPVYPPAIITPLQDTVTSEGQPARFQCRVSGTDLKVSWYSKDKKIKPSRFFRM 3346



 Score =  139 bits (350), Expect = 2e-32
 Identities = 158/612 (25%), Positives = 260/612 (42%), Gaps = 77/612 (12%)

Query: 292   GGRVRFVVELAD-PKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVT 350
             GG +R  V +   P  EVKW K   EIR +   I +       L ++N    D  +Y +T
Sbjct: 16585 GGSLRLFVPIKGRPTPEVKWGKVDGEIRDAA--IIDVTSSFTSLVLDNVNRYDSGKYTLT 16642

Query: 351   AGDEKCSTELFVR-------EPPI--MVTKQLEDTTAYCGERVELECE-------VSEDD 394
               +   +   FV         PP+   VT+  +D+ +   E   L+         V + +
Sbjct: 16643 LENSSGTKSAFVTVRVLDTPSPPVNLKVTEITKDSVSITWEPPLLDGGSKIKNYIVEKRE 16702

Query: 395   ANVKWF--------KNG---EEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTT 443
             A  K +        KN    +++  G    +R+  E +  I        A  A+   +  
Sbjct: 16703 ATRKSYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAENEYGI-----GLPAQTADPIKVAE 16757

Query: 444   GGQSSAKLSVDLKPLKILTPLTDQTVNLG---KEICLKCEISENIPGKWTKNGLPVQESD 500
               Q   K++VD         +T  +V+L     E     +I + I     K+     E  
Sbjct: 16758 VPQPPGKITVD--------DVTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKHSEKWSECA 16809

Query: 501   RLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYN-----------VTLPAKVHVIDPPKI 549
             R+K +      + VI N LT+ E +Y+F   A N           V + AK  VI+P   
Sbjct: 16810 RVKSL------QAVITN-LTQGE-EYLFRVVAVNEKGRSDPRSLAVPIVAKDLVIEP--- 16858

Query: 550   ILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTL 609
               D   A ++ +V  G  L++E+PISG P P   W++ D   ++ + RI      D +TL
Sbjct: 16859 --DVKPAFSSYSVQVGQDLKIEVPISGRPKPTITWTK-DGLPLKQTTRINVTDSLDLTTL 16915

Query: 610   VIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPT-VTEVGDDWCIMNWEPP 668
              I    +DD G Y I + N  G+  ASI++  +D PDPP  P    +V  +   ++W PP
Sbjct: 16916 SIKETHKDDGGQYGITVANVVGQKTASIEIVTLDKPDPPKGPVKFDDVSAESITLSWNPP 16975

Query: 669   AYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGIS 728
              Y GG  I  Y ++++   ++ W  ++  + + TT +  K+  G  Y+ RIFA N  G S
Sbjct: 16976 LYTGGCQITNYIVQKRDTTTTVWDVVSATVAR-TTLKVTKLKTGTEYQFRIFAENRYGQS 17034

Query: 729   KPSMPSRPFV---PLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEG 785
               ++ S P V   P     PP      +++  ++ ++W  P + G + + GY LE     
Sbjct: 17035 F-ALESDPIVAQYPYKEPGPPGTPFATAISKDSMVIQWHEPVNNGGSPVIGYHLERKERN 17093

Query: 786   TEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPK 845
             +  W   NK +I  T+F    L    +   RV A N  G  +    S+  + ++  +PP 
Sbjct: 17094 SILWTKVNKTIIHDTQFKAQNLEEGIEYEFRVYAENIVGVGKASKNSECYVARDPCDPPG 17153

Query: 846   IRIPRHLKQTYI 857
                P  +K+  I
Sbjct: 17154 TPEPIMVKRNEI 17165



 Score =  138 bits (347), Expect = 3e-32
 Identities = 89/302 (29%), Positives = 146/302 (48%), Gaps = 6/302 (1%)

Query: 547   PKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDS 606
             P I+  G +  + + + +G  LR++  + G P P+  W + D   +E    +       S
Sbjct: 21583 PPIVEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVTWFK-DGVEIEKRMNMEITDVLGS 21641

Query: 607   STLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPT-VTEVGDDWCIMNW 665
             ++L +  A RD  GVY +  KN +G A A IKVKV D P   V P   T +  +   + W
Sbjct: 21642 TSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQDTPGKVVGPIRFTNITGEKMTLWW 21701

Query: 666   EPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAI 725
             + P  DG +PI  Y IE+++     W  +  D C+  ++   K+I G  Y+ R+ AVN  
Sbjct: 21702 DAPLNDGCAPITHYIIEKRETSRLAWALIE-DKCEAQSYTAIKLINGNEYQFRVSAVNKF 21760

Query: 726   GISKP--SMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCF 783
             G+ +P  S P    +   V   P +    ++T  ++T+ W  P+  G + +  Y+LE   
Sbjct: 21761 GVGRPLDSDPVVAQIQYTVPDAPGIPEPSNITGNSITLTWARPESDGGSEIQQYILERRE 21820

Query: 784   EGTEDWI-VANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIE 842
             + +  W+ V +K  I +T+F +TGL    +    V A NAAG       S+ I  +E + 
Sbjct: 21821 KKSTRWVKVISKRPISETRFKVTGLTEGNEYEFHVMAENAAGVGPASGISRLIKCREPVN 21880

Query: 843   PP 844
             PP
Sbjct: 21881 PP 21882



 Score =  136 bits (343), Expect = 1e-31
 Identities = 105/376 (27%), Positives = 169/376 (44%), Gaps = 13/376 (3%)

Query: 272  EEKKSAAFAKILDPAYQVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQ 331
            + K+   F + L      +K     F  E ++P ++VKWYK+G E+    KY        
Sbjct: 2123 QAKQLITFTQELQDVVAKEKDTMATFECETSEPFVKVKWYKDGMEVHEGDKYRMHSDRKV 2182

Query: 332  RILFINNCQMTDDSEY-YVTAGDE--KCSTELFVREPPIMVTKQLEDTTAYCGERVELEC 388
              L I     +D  +Y  V   DE  K + +L V    +   K+L+D         ELEC
Sbjct: 2183 HFLSILTIDTSDAEDYSCVLVEDENVKTTAKLIVEGAVVEFVKELQDIEVPESYSGELEC 2242

Query: 389  EVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSS 448
             VS ++   KW+ N  E+      +Y I     +  L ++  TK D  EYS +  G +++
Sbjct: 2243 IVSPENIEGKWYHNDVEL--KSNGKYTITSRRGRQNLTVKDVTKEDQGEYSFVIDGKKTT 2300

Query: 449  AKLSVDLKPLKILTPLTDQTVNLGKEICLKCEIS-ENIPGKWTKNGLPVQESDRLKVVHK 507
             KL +  +P+ IL  L+DQ V  G  + L+ ++S E++ G W K+G  VQ SDR+ +V  
Sbjct: 2301 CKLKMKPRPIAILQGLSDQKVCEGDIVQLEVKVSLESVEGVWMKDGQEVQPSDRVHIVID 2360

Query: 508  GRIHKLVIANALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNK 567
             + H L+I +   ED G+Y F   A  ++   +V V       +D +     V VI G K
Sbjct: 2361 KQSHMLLIEDMTKEDAGNYSFTIPALGLSTSGRVSVYS-----VDVITPLKDVNVIEGTK 2415

Query: 568  LRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLK 627
              LE  +S        W   D+ I +   R++         LVI+     D G Y + + 
Sbjct: 2416 AVLECKVSVPDVTSVKWYLNDEQI-KPDDRVQAIVKGTKQRLVINRTHASDEGPYKLIVG 2474

Query: 628  NEAGEAHASI-KVKVV 642
                  + S+ K+K++
Sbjct: 2475 RVETNCNLSVEKIKII 2490



 Score =  134 bits (338), Expect = 4e-31
 Identities = 201/832 (24%), Positives = 325/832 (39%), Gaps = 120/832 (14%)

Query: 362   VREPPIMVTKQLEDTTAY-CGERVELECEVS-EDDANVKWFKNGEEIIPGPKSRYRIRVE 419
             V  P I V  + +DT     GE   LE +VS      ++W K+G+E+     ++  I++ 
Sbjct: 15084 VEAPKIKVDVKFKDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKEL--EGTAKLEIKIA 15141

Query: 420   GKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKC 479
                  L+ + +T+ D+  Y++  T     AK   ++K L    P  +  + + +    KC
Sbjct: 15142 DFSTNLVNKDSTRRDSGAYTLTATNPGGFAKHIFNVKVLDRPGP-PEGPLAVTEVTSEKC 15200

Query: 480   EISENIP-----GKWTKNGLPVQESDRL---KVVHKGRIHKLVIANALTEDEGDY-VFAP 530
              +S   P      K     +  +E+ RL    V  + ++ KL +   L  +E  + V A 
Sbjct: 15201 VLSWFPPLDDGGAKIDHYIVQKRETSRLAWTNVASEVQVTKLKVTKLLKGNEYIFRVMAV 15260

Query: 531   DAYNVTLPAKVHVI---------DPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPK 581
             + Y V  P +   +         DPPK        +  VT I  + +   +   G P   
Sbjct: 15261 NKYGVGEPLESEPVLAVNPYGPPDPPK--------NPEVTTITKDSM---VVCWGHPDSD 15309

Query: 582   A-------MWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAG--- 631
                     +  R DKA      +   ++  D    V  + E  +   + I  +N AG   
Sbjct: 15310 GGSEIINYIVERRDKAGQRWI-KCNKKTLTDLRYKVSGLTEGHEYE-FRIMAENAAGISA 15367

Query: 632   EAHASIKVKVVDF---PDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQS 688
              +  S   K  D    P PP  P V +       + W  P YDGGS I GY +E    + 
Sbjct: 15368 PSPTSPFYKACDTVFKPGPPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIALPEE 15427

Query: 689   SRWMRLNFDL-CKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSM-PSRPFVPLAVTSPP 746
               W  +      K T++    + E   Y++RI+A+N+ G+ +P++ P  P     +  P 
Sbjct: 15428 DEWQIVTPPAGLKATSYTITGLTENQEYKIRIYAMNSEGLGEPALVPGTPKAEDRMLPPE 15487

Query: 747   TLLTVDSVTDTT----------VTMRWRPPDHIGAAGLDGYVLEYC-FEGTEDW---IVA 792
               L  D     T          V ++ RP   +  A   G  L+    E T  +   IV 
Sbjct: 15488 IELDADLRKVVTIRACCTLRLFVPIKGRPAPEVKWARDHGESLDKASIESTSSYTLLIVG 15547

Query: 793   NKDLIDKTKF--TITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEII--------E 842
             N +  D  K+  T+         FV V+ ++  G        Q + VKE+         +
Sbjct: 15548 NVNRFDSGKYILTVENSSGSKSAFVNVRVLDTPGPP------QDLKVKEVTKTSVTLTWD 15601

Query: 843   PPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTI 902
             PP +     +K  YI    E+             + +WK D  +           E  + 
Sbjct: 15602 PPLLDGGSKIKN-YIVEKRESTRKAYSTVATNCHKTSWKVDQLQ-----------EGCSY 15649

Query: 903   IFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPP 962
              F   AE  +         +    ETA   ++  +RP PP  + + DV   +V+L+W  P
Sbjct: 15650 YFRVLAENEYG--------IGLPAETAE-SVKASERPLPPGKITLMDVTRNSVSLSWEKP 15700

Query: 963   KDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSE 1022
             + DG + I GY ++   K S +W T       T ATIT L+ G EY FRV ++N  G+S+
Sbjct: 15701 EHDGGSRILGYIVEMQTKGSDKWATCAT-VKVTEATITGLIQGEEYSFRVSAQNEKGISD 15759

Query: 1023  DATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAI-AGYNATLNCSVRGNP 1081
                ++    VIA+D  I              P   + L NT+ + AG +  ++    G P
Sbjct: 15760 PRQLSVP--VIAKDLVI--------------PPAFKLLFNTFTVLAGEDLKVDVPFIGRP 15803

Query: 1082  KPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLG 1133
              P +TW K+ V +    R    S +    L I+     D G Y  K  N  G
Sbjct: 15804 TPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAG 15855



 Score =  131 bits (329), Expect = 4e-30
 Identities = 135/530 (25%), Positives = 203/530 (38%), Gaps = 77/530 (14%)

Query: 645   PDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNF-DLCKETT 703
             P PP  P V +       ++W  PAYDGGSPI+GY +E K+  S  W+R N     ++T 
Sbjct: 13217 PGPPAFPKVYDTTRSSVSLSWGKPAYDGGSPIIGYLVEVKRADSDNWVRCNLPQNLQKTR 13276

Query: 704   FEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPP----------TLLTVDS 753
             FE   ++E   Y+ R++AVN IG S PS       P  +  PP          TL+    
Sbjct: 13277 FEVTGLMEDTQYQFRVYAVNKIGYSDPSDVPDKHYPKDILIPPEGELDADLRKTLILRAG 13336

Query: 754   VT-DTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAK 812
             VT    V ++ RPP  I                   W   N +L D+    I    TD  
Sbjct: 13337 VTMRLYVPVKGRPPPKI------------------TWSKPNVNLRDRIGLDIKS--TDFD 13376

Query: 813   IFVRVKAVNAAGASE----------PKYYSQPILVKEIIEPP-KIRIPRHLKQT------ 855
              F+R + VN   A +           K Y+  + V +   PP  + +    K +      
Sbjct: 13377 TFLRCENVNKYDAGKYILTLENSCGKKEYTIVVKVLDTPGPPVNVTVKEISKDSAYVTWE 13436

Query: 856   --YIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHS 913
                I      +N V+  Q +     +W     E  K    + N E     F R    +  
Sbjct: 13437 PPIIDGGSPIINYVV--QKRDAERKSWSTVTTECSKTSFRVANLEEGKSYFFRVFAENEY 13494

Query: 914   GKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGY 973
             G  D     D         ++    PGP   +K+  V   + ++ W  P  DG + I GY
Sbjct: 13495 GIGDPGETRDA--------VKASQTPGPVVDLKVRSVSKSSCSIGWKKPHSDGGSRIIGY 13546

Query: 974   TIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVI 1033
              +    +++ +W  V++       +  +L  G EY FRV +EN  G    + +T    V+
Sbjct: 13547 VVDFLTEEN-KWQRVMKSL-SLQYSAKDLTEGKEYTFRVSAENENGEGTPSEIT----VV 13600

Query: 1034  ARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVA 1093
             ARD     + V  D D    P          A    N  L   ++G P P ++W K +  
Sbjct: 13601 ARD-----DVVAPDLDLKGLPDLCY-----LAKENSNFRLKIPIKGKPAPSVSWKKGEDP 13650

Query: 1094  IVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1143
             +  D R  + S+    TL +      D G Y     N  GT E    ++V
Sbjct: 13651 LATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKEGTISIKV 13700



 Score =  130 bits (328), Expect = 5e-30
 Identities = 80/234 (34%), Positives = 120/234 (51%), Gaps = 8/234 (3%)

Query: 297  FVVELADPKLE-VKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEK 355
            F VEL  P ++ V+W KNG  +  + KY    KG    L I NC + D+S Y    G   
Sbjct: 2680 FTVELTHPNVKGVQWIKNGVVLESNEKYAISVKGTIYSLRIKNCAIVDESVYGFRLGRLG 2739

Query: 356  CSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYR 415
             S  L V    + + K+ +D TA     V  E  VS D   VKWF    EI P  K  +R
Sbjct: 2740 ASARLHVET--VKIIKKPKDVTALENATVAFEVSVSHDTVPVKWFHKSVEIKPSDK--HR 2795

Query: 416  IRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEI 475
            +  E K H L+++  + +DA EY+ +   GQ   K  + ++ L I   + +  V   K  
Sbjct: 2796 LVSERKVHKLMLQNISPSDAGEYTAVV--GQLECKAKLFVETLHITKTMKNIEVPETKTA 2853

Query: 476  CLKCEISE-NIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVF 528
              +CE+S  N+P  W KNG+ ++ S++ K+V +G++H+L+I N  TED  +Y F
Sbjct: 2854 SFECEVSHFNVPSMWLKNGVEIEMSEKFKIVVQGKLHQLIIMNTSTEDSAEYTF 2907



 Score =  129 bits (324), Expect = 2e-29
 Identities = 123/461 (26%), Positives = 196/461 (42%), Gaps = 58/461 (12%)

Query: 488   KWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDY--VFAPDAYNVTLPAKVHVID 545
             KWTK G  +  S R  +       +LVI  A   D G Y  V         +  KV VI 
Sbjct: 23797 KWTKEGQDI--SKRAMIATSETHTELVIKEADRGDSGTYDLVLENKCGKKAVYIKVRVIG 23854

Query: 546   PPKIILDGLDADNTVTVIAGNKLRLEIPISGEPP------------------PKAMWSRG 587
              P      L+ D+             + +S  PP                  PKA W   
Sbjct: 23855 SPNSPEGPLEYDDIQV--------RSVRVSWRPPADDGGADILGYILERREVPKAAWYTI 23906

Query: 588   DKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAG-----EAHASIKVKV- 641
             D        R+R       ++LV+   + +    + ++ +N+ G     ++   +  K  
Sbjct: 23907 DS-------RVR------GTSLVVKGLKENVEYHFRVSAENQFGISKPLKSEEPVTPKTP 23953

Query: 642   VDFPDPPV-APTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCK 700
             ++ P+PP   P V +V      ++W  P  DGGS + GY+IERK+  + +W+R N     
Sbjct: 23954 LNPPEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRVTGYYIERKETSTDKWVRHNKTQIT 24013

Query: 701   ETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFV---PLAVTSPPTLLTVDSVTDT 757
              T +    ++    Y+ RI A N +G+S+ S  S P V   P    S P  L + S++  
Sbjct: 24014 TTMYTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCKDPFDKPSQPGELEILSISKD 24073

Query: 758   TVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRV 817
             +VT++W  P+  G   + GY +EY   G   W  +NK+ I   +FTI GL    +   RV
Sbjct: 24074 SVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERIKDKQFTIGGLLEATEYEFRV 24133

Query: 818   KAVNAAGASEPKYYSQPILVKEII-EPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRP 876
              A N  G S P+  +  I  K    E P IR  + +K     ++GEA  L     G+P P
Sbjct: 24134 FAENETGLSRPRRTAMSIKTKLTSGEAPGIR--KEMKDV-TTKLGEAAQLSCQIVGRPLP 24190

Query: 877   ELTWKKDGAEIDKNQINIRNSETDT-IIFIRKAERSHSGKY 916
             ++ W + G E+ +++    +S+  T  + +   E+   G Y
Sbjct: 24191 DIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVY 24231



 Score =  128 bits (322), Expect = 3e-29
 Identities = 101/352 (28%), Positives = 164/352 (46%), Gaps = 15/352 (4%)

Query: 289  VDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYY 348
            V +G    FV EL+  K+ V W+KN  ++  S   +   +G    L +    + D S+  
Sbjct: 5213 VKEGETATFVCELSHEKMHVVWFKNDAKLHTSRTVLISSEGKTHKLEMKEVTLDDISQIK 5272

Query: 349  VTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIP 408
                +   + +L V E     T +L D TA   + + L+CEVS+ D  VKWFK+GEEI+P
Sbjct: 5273 AQVKELSSTAQLKVLEADPYFTVKLHDKTAVEKDEITLKCEVSK-DVPVKWFKDGEEIVP 5331

Query: 409  GPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQT 468
             PK  Y I+ +G + IL I+ A   D  EY       ++ A ++V+ + +K+  PL    
Sbjct: 5332 SPK--YSIKADGLRRILKIKKADLKDKGEYVCDCGTDKTKANVTVEARLIKVEKPLYGVE 5389

Query: 469  VNLGKEICLKCEISE-NIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYV 527
            V +G+    + E+SE ++ G+W   G P+  S   +++  G+ H L++ N      G+  
Sbjct: 5390 VFVGETAHFEIELSEPDVHGQWKLKGQPLTASPDCEIIEDGKKHILILHNCQLGMTGEVS 5449

Query: 528  FAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRG 587
            F   A N    A + V + P I +  L   + V V   ++ + E  +S E P    W +G
Sbjct: 5450 F--QAANAKSAANLKVKELPLIFITPL---SDVKVFEKDEAKFECEVSRE-PKTFRWLKG 5503

Query: 588  DKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKV 639
             + I  G  R          ++VI  A  +D   Y      EA + H S K+
Sbjct: 5504 TQEI-TGDDRFELIKDGTKHSMVIKSAAFEDEAKYMF----EAEDKHTSGKL 5550



 Score =  127 bits (320), Expect = 5e-29
 Identities = 123/540 (22%), Positives = 217/540 (40%), Gaps = 60/540 (11%)

Query: 622   YHINLKNEAG---EAHASIKVKVVD---FPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSP 675
             Y +  +N AG    +  S  ++  D    P PP  P + + G     + W  P +DGG+P
Sbjct: 19683 YRVYAENAAGLSLPSETSPLIRAEDPVFLPSPPSKPKIVDSGKTTITIAWVKPLFDGGAP 19742

Query: 676   ILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSR 735
             I GY +E KK   + W + +    + T +    +  G  Y  R+ +VN +G S PS  S 
Sbjct: 19743 ITGYTVEYKKSDDTDW-KTSIQSLRGTEYTISGLTTGAEYVFRVKSVNKVGASDPSDSSD 19801

Query: 736   PFVPLAVTSPP----------TLLTVDSVTDT-TVTMRWRPPDHIGAAGLDGYVLEYCFE 784
             P +       P          TL+     + T TV  R RP  ++  +  D  +    + 
Sbjct: 19802 PQIAKEREEEPLFDIDSEMRKTLIVKAGASFTMTVPFRGRPVPNVLWSKPDTDLRTRAYV 19861

Query: 785   GTED----WIVANKDLIDKTKFTIT--GLPTDAKIFVRVKAVNAAGASEPKYYSQPILVK 838
              T D      + N +  D  K+T+T   + + A + + VK ++  G          I V+
Sbjct: 19862 DTTDSRTSLTIENANRNDSGKYTLTIQNVLSAASLTLVVKVLDTPGPPTN------ITVQ 19915

Query: 839   EIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSE 898
             ++ +   +     L        G A       + +   +  W       ++    + N +
Sbjct: 19916 DVTKESAV-----LSWDVPENDGGAPVKNYHIEKREASKKAWVSVTNNCNRLSYKVTNLQ 19970

Query: 899   TDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALT 958
                I + R      SG+ +  V +    ET    ++I ++P PP+ + +  +  ++V+LT
Sbjct: 19971 EGAIYYFRV-----SGENEFGVGIP--AETKE-GVKITEKPSPPEKLGVTSISKDSVSLT 20022

Query: 959   WTPPKDDGNAAITGYTIQKADKKSMEWF--TVIEHYHRTSATITELVIGNEYYFRVFSEN 1016
             W  P+ DG + I  Y ++  +K    W    V +  H   + + E    +EY+FRVF+EN
Sbjct: 20023 WLKPEHDGGSRIVHYVVEALEKGQKNWVKCAVAKSTHHVVSGLRE---NSEYFFRVFAEN 20079

Query: 1017  MCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCS 1076
               GLS+   +            +    + E  +  E  M   P    Y  AG N  ++  
Sbjct: 20080 QAGLSDPREL------------LLPVLIKEQLEPPEIDMKNFPSHTVYVRAGSNLKVDIP 20127

Query: 1077  VRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVE 1136
             + G P PK+T  ++ V +    R+         T+ +++    D G Y   A N  GT +
Sbjct: 20128 ISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADAGRYEITAANSSGTTK 20187



 Score =  125 bits (315), Expect = 2e-28
 Identities = 87/266 (32%), Positives = 123/266 (46%), Gaps = 11/266 (4%)

Query: 272  EEKKSAAFAKIL--DPAYQV---DKGGRVRFVVEL---ADPKLEVKWYKNGQEIRPSTKY 323
            +E  S A  K+L  DP + V   DK    +  + L       + VKW+K+G+EI PS KY
Sbjct: 5276 KELSSTAQLKVLEADPYFTVKLHDKTAVEKDEITLKCEVSKDVPVKWFKDGEEIVPSPKY 5335

Query: 324  IFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGER 383
              +  G +RIL I    + D  EY    G +K    + V    I V K L     + GE 
Sbjct: 5336 SIKADGLRRILKIKKADLKDKGEYVCDCGTDKTKANVTVEARLIKVEKPLYGVEVFVGET 5395

Query: 384  VELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTT 443
               E E+SE D + +W   G+ +   P     I  +GKKHILI+         E S    
Sbjct: 5396 AHFEIELSEPDVHGQWKLKGQPLTASPDC--EIIEDGKKHILILHNCQLGMTGEVSFQAA 5453

Query: 444  GGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCEIS-ENIPGKWTKNGLPVQESDRL 502
              +S+A L V   PL  +TPL+D  V    E   +CE+S E    +W K    +   DR 
Sbjct: 5454 NAKSAANLKVKELPLIFITPLSDVKVFEKDEAKFECEVSREPKTFRWLKGTQEITGDDRF 5513

Query: 503  KVVHKGRIHKLVIANALTEDEGDYVF 528
            +++  G  H +VI +A  EDE  Y+F
Sbjct: 5514 ELIKDGTKHSMVIKSAAFEDEAKYMF 5539



 Score =  122 bits (306), Expect = 2e-27
 Identities = 197/849 (23%), Positives = 321/849 (37%), Gaps = 123/849 (14%)

Query: 344   DSEYYVTAGDEKCSTELFVREPPIMVTKQLEDTTAY-CGERVELECEV-SEDDANVKWFK 401
             DS   +TA DE       V  P I +  +  DT     GE   LE +V  +    ++W +
Sbjct: 17237 DSTGPITAKDE-------VELPRISMDPKFRDTIVVNAGETFRLEADVHGKPLPTIEWLR 17289

Query: 402   NGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKIL 461
               +EI     +R  I+    K +LI++ A + D  +Y +  +    S    V++K L   
Sbjct: 17290 GDKEI--EESARCEIKNTDFKALLIVKDAIRIDGGQYILRASNVAGSKSFPVNVKVLDRP 17347

Query: 462   TPLTDQTVNLGKEICLKCEISENIPGKWTKNGLPVQESDRLKVVHKGRIHKL-------- 513
              P  +  V +      KC ++ + P +    G  +       VV K    +L        
Sbjct: 17348 GP-PEGPVQVTGVTSEKCSLTWSPPLQ--DGGSDISHY----VVEKRETSRLAWTVVASE 17400

Query: 514   VIANALTEDE----GDYVF---APDAYNVTLPAK-VHVIDPPKIILDGLDADNTVTVIAG 565
             V+ N+L   +     +YVF   A + Y V  P +   V+     +L G      VT IA 
Sbjct: 17401 VVTNSLKVTKLLEGNEYVFRIMAVNKYGVGEPLESAPVLMKNPFVLPGPPKSLEVTNIAK 17460

Query: 566   NKLRLEIPISGEPPPKAMWSRGDKA--------IMEGSGRIRTESYPDSSTLVIDIAER- 616
             + + +             W+R D          I+E   R        +   + D+  R 
Sbjct: 17461 DSMTV------------CWNRPDSDGGSEIIGYIVEKRDRSGIRWIKCNKRRITDLRLRV 17508

Query: 617   -----DDSGVYHINLKNEAGEAH---ASIKVKVVD---FPDPPVAPTVTEVGDDWCIMNW 665
                  D    + ++ +N AG      A++  K  D    P PP    + +   +   + W
Sbjct: 17509 TGLTEDHEYEFRVSAENAAGVGEPSPATVYYKACDPVFKPGPPTNAHIVDTTKNSITLAW 17568

Query: 666   EPPAYDGGSPILGYFIERKKKQSSRWMRLNFDL-CKETTFEPKKMIEGVAYEVRIFAVNA 724
               P YDGGS ILGY +E  K     W  +      + T FE  K+ E   Y++R+ A+N 
Sbjct: 17569 GKPIYDGGSEILGYVVEICKADEEEWQIVTPQTGLRVTRFEISKLTEHQEYKIRVCALNK 17628

Query: 725   IGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMR------------WRPPDHIGAA 772
             +G+ + +       P      P L  +DS     + +R             RP   I  +
Sbjct: 17629 VGLGEATSVPGTVKPEDKLEAPEL-DLDSELRKGIVVRAGGSARIHIPFKGRPTPEITWS 17687

Query: 773   GLDG-YVLEYCFEGTEDWI---VANKDLIDKTKFTIT--GLPTDAKIFVRVKAVNAAGAS 826
               +G +  +   E   ++    + N D  D  K+ +           FV VK ++  G  
Sbjct: 17688 REEGEFTDKVQIEKGVNYTQLSIDNCDRNDAGKYILKLENSSGSKSAFVTVKVLDTPGPP 17747

Query: 827   EPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAE 886
                   Q + VKE+ +     +    +   I    +  N VI  +   R    +    ++
Sbjct: 17748 ------QNLAVKEVRKDSAFLV---WEPPIIDGGAKVKNYVIDKRESTRK--AYANVSSK 17796

Query: 887   IDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVK 946
               K    + N     I + R    +  G       V   VET    ++  + P PP  V 
Sbjct: 17797 CSKTSFKVENLTEGAIYYFRVMAENEFG-------VGVPVETVDA-VKAAEPPSPPGKVT 17848

Query: 947   IEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGN 1006
             + DV   + +L W  P+ DG + + GY ++   K + +W  V E     +A +T L  G 
Sbjct: 17849 LTDVSQTSASLMWEKPEHDGGSRVLGYVVEMQPKGTEKWSIVAES-KVCNAVVTGLSSGQ 17907

Query: 1007  EYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAI 1066
             EY FRV + N  G S+   +     VIA+D  I              P    P  NTY+I
Sbjct: 17908 EYQFRVKAYNEKGKSDPRVLGVP--VIAKDLTIQ-------------PSLKLPF-NTYSI 17951

Query: 1067  -AGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYC 1125
              AG +  +   V G P+P I+W+K+   +    R  +        L I++ +  D G Y 
Sbjct: 17952 QAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKYT 18011

Query: 1126  CKAVNDLGT 1134
               A N  GT
Sbjct: 18012 VTATNSAGT 18020



 Score =  121 bits (304), Expect = 3e-27
 Identities = 185/870 (21%), Positives = 323/870 (37%), Gaps = 146/870 (16%)

Query: 338   NCQMTDDSEYYVTAGDEKCSTELFVREPPIMVTKQLEDT-TAYCGERVELECEV-SEDDA 395
             N     DS   +TA DE       +  P   +  + +D    + GE   LE ++  +   
Sbjct: 18313 NFSEPSDSSGAITARDE-------IDAPNASLDPKYKDVIVVHAGETFVLEADIRGKPIP 18365

Query: 396   NVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEY--SVMTTGGQSSAKLSV 453
             +V W K+G+E+     +R  I+   +K  L+++   + D  +Y   +   GG  S  ++V
Sbjct: 18366 DVVWSKDGKEL-EETAARMEIKSTIQKTTLVVKDCIRTDGGQYILKLSNVGGTKSIPITV 18424

Query: 454   DLK--------PLKIL------------TPLTDQTVNLGKEICLKCEISENIPGKWTKNG 493
              +         PLK+              PL D   N+   I  K E S      WT+  
Sbjct: 18425 KVLDRPGPPEGPLKVTGVTAEKCYLAWNPPLQDGGANISHYIIEKRETSRL---SWTQVS 18481

Query: 494   LPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVF---APDAYNVTLPAKVHVID----- 545
               VQ  +        ++ KL+  N       +Y+F   A + Y +  P +   +      
Sbjct: 18482 TEVQALNY-------KVTKLLPGN-------EYIFRVMAVNKYGIGEPLESGPVTACNPY 18527

Query: 546   -----PPKIILDGLDADNTVTVIA------GNKLRLEIPISGEPPPKAMWSRGDKAIMEG 594
                  P    +  +  D+ V   A      G ++   I +         W++ +K  +  
Sbjct: 18528 KPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYI-LEKRDKEGVRWTKCNKKTLTD 18586

Query: 595   SGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGE-AHASIKVKVVDF---PDPPVA 650
               R+R     +  +    +A  + +GV         GE +  S+  +  D    P PP  
Sbjct: 18587 L-RLRVTGLTEGHSYEFRVAAENAAGV---------GEPSEPSVFYRACDALYPPGPPSN 18636

Query: 651   PTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETT------F 704
             P VT+       + W  P YDGG+P+ GY +E K+  +  W       C   T      F
Sbjct: 18637 PKVTDTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAADEWTT-----CTPPTGLQGKQF 18691

Query: 705   EPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTL-----------LTVDS 753
                K+ E   Y  RI A+N+ G+ +P+      V      PP +           L   +
Sbjct: 18692 TVTKLKENTEYNFRICAINSEGVGEPATLPGSVVAQERIEPPEIELDADLRKVVVLRASA 18751

Query: 754   VTDTTVTMRWRPPDHIGAAGLDGYVLEYC-FEGTEDW---IVANKDLIDKTKFTIT--GL 807
                  VT++ RP   +     +G + +    E T  +   ++ N    D  ++ +T    
Sbjct: 18752 TLRLFVTIKGRPEPEVKWEKAEGILTDRAQIEVTSSFTMLVIDNVTRFDSGRYNLTLENN 18811

Query: 808   PTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLV 867
                   FV V+ +++  A        P+ +  I E  K  +    +   I    +  N +
Sbjct: 18812 SGSKTAFVNVRVLDSPSA--------PVNLT-IREVKKDSVTLSWEPPLIDGGAKITNYI 18862

Query: 868   IPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVE 927
             +  +   R       +     K    I N +     + R      S +Y + +  +    
Sbjct: 18863 VEKRETTRKAYATITNNCT--KTTFRIENLQEGCSYYFRVLA---SNEYGIGLPAE---- 18913

Query: 928   TASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFT 987
               +  +++ + P PP  V + DV      + W  P+ DG + ITGY ++   K S +W T
Sbjct: 18914 -TTEPVKVSEPPLPPGRVTLVDVTRNTATIKWEKPESDGGSKITGYVVEMQTKGSEKWST 18972

Query: 988   VIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYED 1047
               +      ATI+ L  G EY FRV + N  G S+   +     VIARD +I        
Sbjct: 18973 CTQ-VKTLEATISGLTAGEEYVFRVAAVNEKGRSDPRQLGVP--VIARDIEI-------- 19021

Query: 1048  FDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQG 1107
                   P    P       A     ++   +G P+  + W K+   + +  R  + S++ 
Sbjct: 19022 -----KPSVELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKT 19076

Query: 1108  VCTLEIRKPSPYDGGTYCCKAVNDLGTVEI 1137
             V +L I++ S  D GTY     N  G++ +
Sbjct: 19077 VTSLSIKEASKEDVGTYELCVSNSAGSITV 19106



 Score =  120 bits (302), Expect = 6e-27
 Identities = 142/561 (25%), Positives = 214/561 (38%), Gaps = 83/561 (14%)

Query: 622   YHINLKNEAGEAHASIKVKVVDF------PDPPVAPTVTEVGDDWCIMNWEPPAYDGGSP 675
             + ++ +NE G    S   K V        P PPV P   +   +   + W+PP +DGGS 
Sbjct: 10712 FRVSAENEIGIGDPSPPSKPVFAKDPIAKPSPPVNPEAIDTTCNSVDLTWQPPRHDGGSK 10771

Query: 676   ILGYFIERKKKQSSRWMRLNF--DLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMP 733
             ILGY +E +K     W R N   + C ET ++   + +G  Y+ R+ AVNA G S P+  
Sbjct: 10772 ILGYIVEYQKVGDEEWRRANHTPESCPETKYKVTGLRDGQTYKFRVLAVNAAGESDPAHV 10831

Query: 734   SRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTE----DW 789
               P +      PP L     + D  +        HI     D   L    +G       W
Sbjct: 10832 PEPVLVKDRLEPPEL-----ILDANMARE----QHIKVG--DTLRLSAIIKGVPFPKVTW 10880

Query: 790   IVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAG----ASEPKYYSQPILVKEIIEPPK 845
                ++D   K +  +T  P  +K+ +R  A    G      E    S+ + VK ++   K
Sbjct: 10881 KKEDRDAPTKARIDVT--PVGSKLEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLD-K 10937

Query: 846   IRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKK---DGAEIDKNQINIRNSETD-- 900
                PR L+ + IR              K    LTWK+   DG  +  N +  R       
Sbjct: 10938 PGPPRDLEVSEIR--------------KDSCYLTWKEPLDDGGSVITNYVVERRDVASAQ 10983

Query: 901   -TIIFIRKAERSHSGKY-------------DLQVKVDKFVETASIDIQIIDR---PGPPQ 943
              + +     ++SH  K+             + Q     FVET    I+ +D    PGPP+
Sbjct: 10984 WSPLSATSKKKSHFAKHLNEGNQYLFRVAAENQYGRGPFVETPK-PIKALDPLHPPGPPK 11042

Query: 944   IVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELV 1003
              +   DV    V+L W  P  DG + ITGY ++  ++ + +W    +        +T L 
Sbjct: 11043 DLHHVDVDKTEVSLVWNKPDRDGGSPITGYLVEYQEEGTQDWIK-FKTVTNLECVVTGLQ 11101

Query: 1004  IGNEYYFRVFSENMCGLS-EDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVN 1062
              G  Y FRV +EN+ GL   D T+  E        K+    V  D    E  +       
Sbjct: 11102 QGKTYRFRVKAENIVGLGLPDTTIPIEC-----QEKLVPPSVELDVKLIEGLVVK----- 11151

Query: 1063  TYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGG 1122
                 AG        +RG P P   W  +   I  D  Y + ++     L I+     D G
Sbjct: 11152 ----AGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTG 11207

Query: 1123  TYCCKAVNDLGTVEIECKLEV 1143
              Y     N  G+  +   L V
Sbjct: 11208 EYQITVSNAAGSKTVAVHLTV 11228



 Score =  120 bits (301), Expect = 7e-27
 Identities = 130/513 (25%), Positives = 208/513 (40%), Gaps = 41/513 (7%)

Query: 121  KGKWMDLASKAGKHLQLKETFERHSRVYTFEMQIIKAKDNFAGNYRCEVTYKDKFDSCSF 180
            KG+W+    + GKHL L       S  +   + I   K +  G Y    TYK      S 
Sbjct: 2603 KGEWL----RDGKHLPLTNNIRSESDGHKRRLIIAATKLDDIGEY----TYKVATSKTSA 2654

Query: 181  DLEVH--ESTGTTPNIDIRSAFKRSGEGQEDAGELDFSGLLKRREVKQQEEEPQVDVWEL 238
             L+V   +   T  N+ +          +     +     +K   V +  E+  + V   
Sbjct: 2655 KLKVEAVKIKKTLKNLTVTETQDAVFTVELTHPNVKGVQWIKNGVVLESNEKYAISV--- 2711

Query: 239  LKNAKPSEYEKIAFQYGITDLRGMLKRLKRMRREEKKSAAFAKILDPAYQVD--KGGRVR 296
                K + Y        I D      RL R+    +      KI+     V   +   V 
Sbjct: 2712 ----KGTIYSLRIKNCAIVDESVYGFRLGRLGASARLHVETVKIIKKPKDVTALENATVA 2767

Query: 297  FVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKC 356
            F V ++   + VKW+    EI+PS K+    +     L + N   +D  EY    G  +C
Sbjct: 2768 FEVSVSHDTVPVKWFHKSVEIKPSDKHRLVSERKVHKLMLQNISPSDAGEYTAVVGQLEC 2827

Query: 357  STELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRI 416
              +LFV    + +TK +++      +    ECEVS  +    W KNG EI    K  ++I
Sbjct: 2828 KAKLFVE--TLHITKTMKNIEVPETKTASFECEVSHFNVPSMWLKNGVEIEMSEK--FKI 2883

Query: 417  RVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEIC 476
             V+GK H LII   +  D+AEY+ +    Q SA L+V   P+ I + L D  +N  ++  
Sbjct: 2884 VVQGKLHQLIIMNTSTEDSAEYTFVCGNDQVSATLTV--TPIMITSMLKD--INAEEKDT 2939

Query: 477  LKCEISENIPG---KWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPD-- 531
            +  E++ N  G   KW KNG+ ++ +D+ ++  K   H L I N    D  DY F     
Sbjct: 2940 ITFEVTVNYEGISYKWLKNGVEIKSTDKCQMRTKKLTHSLNIRNVHFGDAADYTFVAGKA 2999

Query: 532  AYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAI 591
                TL  +   I+  K I D       + V+   +   E  +S EP     W + D+  
Sbjct: 3000 TSTATLYVEARHIEFRKHIKD-------IKVLEKKRAMFECEVS-EPDITVQWMKDDQE- 3050

Query: 592  MEGSGRIRTESYPDSSTLVIDIAERDDSGVYHI 624
            ++ + RI+ +       L+I      D+G Y +
Sbjct: 3051 LQITDRIKIQKEKYVHRLLIPSTRMSDAGKYTV 3083



 Score =  120 bits (301), Expect = 7e-27
 Identities = 89/317 (28%), Positives = 143/317 (45%), Gaps = 11/317 (3%)

Query: 281  KILDPAYQVD--KGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINN 338
            K++ P + V+  +    RF  E+++  +   W   G+ +  +     + +G    L ++N
Sbjct: 5736 KLVRPLHSVEVMETETARFETEISEDDIHANWKLKGEALLQTPDCEIKEEGKIHSLVLHN 5795

Query: 339  CQMTDDSEYYVTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVK 398
            C++         A + K S  L V+   I + + L+D T   GE    +CE+S +D  V+
Sbjct: 5796 CRLDQTGGVDFQAANVKSSAHLRVKPRVIGLLRPLKDVTVTAGETATFDCELSYEDIPVE 5855

Query: 399  WFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPL 458
            W+  G+++ P  K     R EGK H L +      DA E  +     ++ A L V   P+
Sbjct: 5856 WYLKGKKLEPSDK--VVPRSEGKVHTLTLRDVKLEDAGEVQLTAKDFKTHANLFVKEPPV 5913

Query: 459  KILTPLTDQTVNLGKEICLKCEIS-ENIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIAN 517
            +   PL DQTV  G    L+CE+S EN   KW KNG  + +S + ++V  GR+ KLVI +
Sbjct: 5914 EFTKPLEDQTVEEGATAVLECEVSRENAKVKWFKNGTEILKSKKYEIVADGRVRKLVIHD 5973

Query: 518  ALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGE 577
               ED   Y    DA +      ++V+ P    L  L     + V      R E  +S E
Sbjct: 5974 CTPEDIKTYTC--DAKDFKTSCNLNVVPPHVEFLRPL---TDLQVREKEMARFECELSRE 6028

Query: 578  PPPKAMWSRGDKAIMEG 594
               K  W +    I +G
Sbjct: 6029 -NAKVKWFKDGAEIKKG 6044



 Score =  119 bits (298), Expect = 2e-26
 Identities = 113/439 (25%), Positives = 181/439 (41%), Gaps = 46/439 (10%)

Query: 621   VYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYF 680
             V  INL      +  S  V  +D  DPP  P V  +  +   + W  P YDGG  + GY 
Sbjct: 13878 VMAINLAGVGKPSLPSEPVVALDPIDPPGKPEVINITRNSVTLIWTEPKYDGGHKLTGYI 13937

Query: 681   IERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIG-ISKPSMPSRPFVP 739
             +E++   S  WM+ N     E  F    ++EG  YE RI A N  G IS PS  +   + 
Sbjct: 13938 VEKRDLPSKSWMKANHVNVPECAFTVTDLVEGGKYEFRIRAKNTAGAISAPSESTETIIC 13997

Query: 740   LAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDK 799
                   PT++   ++ D  +T++      + A  + G  L         W  A KD+   
Sbjct: 13998 KDEYEAPTIVLDPTIKD-GLTIKAGDTIVLNAISILGKPLP-----KSSWSKAGKDIRPS 14051

Query: 800   TKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRR 859
                 IT  PT + + ++      AG       + P   K            H+K T +  
Sbjct: 14052 DITQITSTPTSSMLTIKYATRKDAG-EYTITATNPFGTK----------VEHVKVTVLDV 14100

Query: 860   VGEAVNLVIPFQGKPRPELTWK---KDGAEIDKNQINIRNSETDTIIFIRKAERSHS--- 913
              G    + I      +  LTW    +DG    K+ I +   ET  +++   +E   S   
Sbjct: 14101 PGPPGPVEISNVSAEKATLTWTPPLEDGGSPIKSYI-LEKRETSRLLWTVVSEDIQSCRH 14159

Query: 914   --------GKYDLQVKV----DKFVETASIDIQIIDR---PGPPQIVKIEDVWGENVALT 958
                      +Y  +V       K     S  ++++DR   PGPP+  ++ +V      ++
Sbjct: 14160 VATKLIQGNEYIFRVSAVNHYGKGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTATVS 14219

Query: 959   WTPPKDDGNAAITGYTIQKADKKSMEWFTVIE-HYHRTSATITELVIGNEYYFRVFSENM 1017
             W  P DDG + ITGY +++ +KKS+ W   I+         +T L  G+ Y FRV +EN 
Sbjct: 14220 WKRPVDDGGSEITGYHVERREKKSLRWVRAIKTPVSDLRCKVTGLQEGSTYEFRVSAENR 14279

Query: 1018  CGL-----SEDATMTKESA 1031
              G+     + D+ + K++A
Sbjct: 14280 AGIGPPSEASDSVLMKDAA 14298



 Score =  116 bits (291), Expect = 1e-25
 Identities = 187/859 (21%), Positives = 324/859 (37%), Gaps = 143/859 (16%)

Query: 349   VTAGDEKCSTELFVREPPIMVTKQLEDT-TAYCGERVELECEV-SEDDANVKWFKNGEEI 406
             +TA DE       V  P I +  + +DT   + GE  +++ ++  +    ++W K  +E+
Sbjct: 16160 ITARDE-------VDPPRISMDPKYKDTIVVHAGESFKVDADIYGKPIPTIQWIKGDQEL 16212

Query: 407   IPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTD 466
                  +R  I+       L ++ A + D+  Y +          ++V++K L    P   
Sbjct: 16213 --SNTARLEIKSTDFATSLSVKDAVRVDSGNYILKAKNVAGERSVTVNVKVLDRPGPPEG 16270

Query: 467   QTVNLGKEICLKCEISENIPGKWTKNGLPVQE--SDRLKVVHKGR-----IHKLVIANAL 519
               V  G     KC ++      W     P+Q+  SD +  + + R     +  +V AN  
Sbjct: 16271 PVVISGVT-AEKCTLA------WKP---PLQDGGSDIINYIVERRETSRLVWTVVDANVQ 16320

Query: 520   TED-------EG-DYVF---APDAYNVTLPAKVH--VIDPPKIILDGLDADNTVTVIAGN 566
             T         EG +Y F   A + Y V  P +    V   P ++ D   A    TV   +
Sbjct: 16321 TLSCKVTKLLEGNEYTFRIMAVNKYGVGEPLESEPVVAKNPFVVPDAPKAPEVTTVTKDS 16380

Query: 567   KLRL-EIPISG------------EPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDI 613
              + + E P S                    W+R  K ++ G  R+R          V  +
Sbjct: 16381 MIVVWERPASDGGSEILGYVLEKRDKEGIRWTRCHKRLI-GELRLR----------VTGL 16429

Query: 614   AERDDSGVYHINLKNEAGEAHAS---IKVKVVD---FPDPPVAPTVTEVGDDWCIMNWEP 667
              E  D   + ++ +N AG +  S      K  D    P PP  P V ++      ++W  
Sbjct: 16430 IENHDYE-FRVSAENAAGLSEPSPPSAYQKACDPIYKPGPPNNPKVIDITRSSVFLSWSK 16488

Query: 668   PAYDGGSPILGYFIERKKKQSSRWMRLNFDL-CKETTFEPKKMIEGVAYEVRIFAVNAIG 726
             P YDGG  I GY +E+       W          +T  E +K++E   Y  RI A+N  G
Sbjct: 16489 PIYDGGCEIQGYIVEKCDVSVGEWTMCTPPTGINKTNIEVEKLLEKHEYNFRICAINKAG 16548

Query: 727   ISKPSMPSRPFVPLAVTSPPTL-----------LTVDSVTDTTVTMRWRPPDHIGAAGLD 775
             + + +    P +       P +           +         V ++ RP   +    +D
Sbjct: 16549 VGEHADVPGPIIVEEKLEAPDIDLDLELRKIINIRAGGSLRLFVPIKGRPTPEVKWGKVD 16608

Query: 776   GYVLEYCF----EGTEDWIVANKDLIDKTKFTIT--GLPTDAKIFVRVKAVNAAGASEPK 829
             G + +             ++ N +  D  K+T+T          FV V+ ++    S P 
Sbjct: 16609 GEIRDAAIIDVTSSFTSLVLDNVNRYDSGKYTLTLENSSGTKSAFVTVRVLDTP--SPPV 16666

Query: 830   YYSQPILVKEII----EPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGA 885
                   + K+ +    EPP +     +K   + +                 E T K   A
Sbjct: 16667 NLKVTEITKDSVSITWEPPLLDGGSKIKNYIVEK----------------REATRKSYAA 16710

Query: 886   EID---KNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPP 942
              +    KN   I   +     + R    +  G       +    +TA   I++ + P PP
Sbjct: 16711 VVTNCHKNSWKIDQLQEGCSYYFRVTAENEYG-------IGLPAQTAD-PIKVAEVPQPP 16762

Query: 943   QIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITEL 1002
               + ++DV   +V+L+WT P+ DG + I  Y ++   K S +W +         A IT L
Sbjct: 16763 GKITVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKHSEKW-SECARVKSLQAVITNL 16821

Query: 1003  VIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVN 1062
               G EY FRV + N  G S+  ++     ++A+D  I  +               +P  +
Sbjct: 16822 TQGEEYLFRVVAVNEKGRSDPRSLAVP--IVAKDLVIEPD--------------VKPAFS 16865

Query: 1063  TYAI-AGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDG 1121
             +Y++  G +  +   + G PKP ITW K+ + +    R  +  +  + TL I++    DG
Sbjct: 16866 SYSVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDG 16925

Query: 1122  GTYCCKAVNDLG--TVEIE 1138
             G Y     N +G  T  IE
Sbjct: 16926 GQYGITVANVVGQKTASIE 16944



 Score =  115 bits (287), Expect = 3e-25
 Identities = 101/370 (27%), Positives = 158/370 (42%), Gaps = 34/370 (9%)

Query: 291  KGGRVRFVVELAD-----------------PKLEVKWYKNGQEIRPSTKYIFEHKGCQRI 333
            +G  V FV EL D                   +E KWY N  E++ + KY    +  ++ 
Sbjct: 2217 EGAVVEFVKELQDIEVPESYSGELECIVSPENIEGKWYHNDVELKSNGKYTITSRRGRQN 2276

Query: 334  LFINNCQMTDDSEYYVTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSED 393
            L + +    D  EY      +K + +L ++  PI + + L D     G+ V+LE +VS +
Sbjct: 2277 LTVKDVTKEDQGEYSFVIDGKKTTCKLKMKPRPIAILQGLSDQKVCEGDIVQLEVKVSLE 2336

Query: 394  DANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSV 453
                 W K+G+E+   P  R  I ++ + H+L+IE  TK DA  YS        S    V
Sbjct: 2337 SVEGVWMKDGQEV--QPSDRVHIVIDKQSHMLLIEDMTKEDAGNYSFTIPALGLSTSGRV 2394

Query: 454  DLKPLKILTPLTDQTVNLGKEICLKCEIS--ENIPGKWTKNGLPVQESDRLKVVHKGRIH 511
             +  + ++TPL D  V  G +  L+C++S  +    KW  N   ++  DR++ + KG   
Sbjct: 2395 SVYSVDVITPLKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVKGTKQ 2454

Query: 512  KLVIANALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLE 571
            +LVI      DEG Y              V  I     I+ GL  D T T        +E
Sbjct: 2455 RLVINRTHASDEGPYKLIVGRVETNCNLSVEKIK----IIRGL-RDLTCTETQNVVFEVE 2509

Query: 572  IPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAG 631
            +  SG      +W+  DK I + S + + E++     L +    +DD G Y       AG
Sbjct: 2510 LSHSG---IDVLWNFKDKEI-KPSSKYKIEAHGKIYKLTVLNMMKDDEGKYTF----YAG 2561

Query: 632  EAHASIKVKV 641
            E   S K+ V
Sbjct: 2562 ENMTSGKLTV 2571



 Score =  115 bits (287), Expect = 3e-25
 Identities = 182/792 (22%), Positives = 302/792 (38%), Gaps = 105/792 (13%)

Query: 398   KWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKP 457
             KW  +G EI       Y +  +    +L I+   + D  EY +  +    S  ++V L  
Sbjct: 11171 KWTTDGSEI--KTDEHYTVETDNFSSVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTV 11228

Query: 458   LKILTPLTDQTVNLG---KEICLKCEISENIPGKWTKNGLPVQESDRLK----VVHKGRI 510
             L +  P T     L    + + +  +  ++  G    N + V++ D  K    VV  G  
Sbjct: 11229 LDVPGPPTGPINILDVTPEHMTISWQPPKDDGGSPVINYI-VEKQDTRKDTWGVVSSGSS 11287

Query: 511   H-KLVIANALTEDEGDYVFAPDAYNV---------TLPAKVHVIDPPKIILDGLDADNTV 560
               KL I +   +   +YVF   A N          T     H   PP            V
Sbjct: 11288 KTKLKIPHL--QKGCEYVFRVRAENKIGVGPPLDSTPTVAKHKFSPPSP-----PGKPVV 11340

Query: 561   TVIAGNKLRLE--IPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERD- 617
             T I  N   +   +P S    P   +    + +     R+      D    V  + E + 
Sbjct: 11341 TDITENAATVSWTLPKSDGGSPITGYYMERREVTGKWVRVNKTPIADLKFRVTGLYEGNT 11400

Query: 618   -DSGVYHINLKNEAGEAHASIKVKV---VDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGG 673
              +  V+  NL   +  + +S  +K    +  P PP+ P + +   +   + W  P  DGG
Sbjct: 11401 YEFRVFAENLAGLSKPSPSSDPIKACRPIKPPGPPINPKLKDKSRETADLVWTKPLSDGG 11460

Query: 674   SPILGYFIERKKKQSSRWMRLNFD-LCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSM 732
             SPILGY +E +K  +++W R+N D L ++  F    +IEG  Y  RI A N +G  +P  
Sbjct: 11461 SPILGYVVECQKPGTAQWNRINKDELIRQCAFRVPGLIEGNEYRFRIKAANIVGEGEPRE 11520

Query: 733   PSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVA 792
              +   +   +  PP +  +D      +T+R      I  A + G       E    W   
Sbjct: 11521 LAESVIAKDILHPPEV-ELDVTCRDVITVRVGQTIRI-LARVKGRP-----EPDITWTKE 11573

Query: 793   NKDLI-DKTKFTITGLPTDAKIFVRVKAVNAAGASEPKY---------YSQPILVKEIIE 842
              K L+ +K    I  LP      V ++   A  A   KY         ++Q   +  +++
Sbjct: 11574 GKVLVREKRVDLIQDLPR-----VELQIKEAVRADHGKYIISAKNSSGHAQGSAIVNVLD 11628

Query: 843   PPKIRIPRHLKQTYIRRVG--------------EAVNLVIPFQGKPRPELTWKKDGAEID 888
              P     ++LK T + +                E  N ++ ++ KP  +  W    +++ 
Sbjct: 11629 RPGPC--QNLKVTNVTKENCTISWENPLDNGGSEITNFIVEYR-KPNQK-GWSIVASDVT 11684

Query: 889   KNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETAS--IDIQIIDRPGPPQIVK 946
             K  I       +   F   AE         +V V   +ET +  + I  IDRPG P+ + 
Sbjct: 11685 KRLIKANLLANNEYYFRVCAEN--------KVGVGPTIETKTPILAINPIDRPGEPENLH 11736

Query: 947   IEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGN 1006
             I D     V L W  P  DG +    Y +++  K S +W  V +   + +  + +  + N
Sbjct: 11737 IADKGKTFVYLKWRRPDYDGGSPNLSYHVERRLKGSDDWERVHKGSIKETHYMVDRCVEN 11796

Query: 1007  EYY-FRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYA 1065
             + Y FRV ++N  G S+   +  E  V+  D               + P+    L     
Sbjct: 11797 QIYEFRVQTKNEGGESD--WVKTEEVVVKED--------------LQKPVLDLKLSGVLT 11840

Query: 1066  I-AGYNATLNCSVRGNPKPKITWMKNKVA--IVDDPRYRMFSNQGVCTLEIRKPSPYDGG 1122
             + AG    L   VRG P P++ W K+K A  +   PR ++ +        + K    DGG
Sbjct: 11841 VKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKAKRSDGG 11900

Query: 1123  TYCCKAVNDLGT 1134
              Y   A N  G+
Sbjct: 11901 KYVVTATNTAGS 11912



 Score =  112 bits (280), Expect = 2e-24
 Identities = 102/419 (24%), Positives = 166/419 (39%), Gaps = 35/419 (8%)

Query: 744   SPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFT 803
             SP   L  D +   +V + WRPP   G A + GY+LE        W   +   +  T   
Sbjct: 23858 SPEGPLEYDDIQVRSVRVSWRPPADDGGADILGYILERREVPKAAWYTIDSR-VRGTSLV 23916

Query: 804   ITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEA 863
             + GL  + +   RV A N  G S+P    +P+  K  + PP+   P       +     +
Sbjct: 23917 VKGLKENVEYHFRVSAENQFGISKPLKSEEPVTPKTPLNPPE---PPSNPPEVLDVTKSS 23973

Query: 864   VNLVIPFQGKPRPELTWKKDGAEIDKNQIN----IRNSETD-TIIFIRKAERSHSGKYDL 918
             V+L      +P+ +   +  G  I++ + +    +R+++T  T             +Y  
Sbjct: 23974 VSLS---WSRPKDDGGSRVTGYYIERKETSTDKWVRHNKTQITTTMYTVTGLVPDAEYQF 24030

Query: 919   QVKVDKFV---ETASIDIQII-----DRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAI 970
             ++     V   ET+     ++     D+P  P  ++I  +  ++V L W  P+ DG   I
Sbjct: 24031 RIIAQNDVGLSETSPASEPVVCKDPFDKPSQPGELEILSISKDSVTLQWEKPECDGGKEI 24090

Query: 971   TGYTIQKADKKSMEWF-TVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKE 1029
              GY ++        W  +  E       TI  L+   EY FRVF+EN  GLS        
Sbjct: 24091 LGYWVEYRQSGDSAWKKSNKERIKDKQFTIGGLLEATEYEFRVFAENETGLSRPRRTAMS 24150

Query: 1030  SAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMK 1089
                    G              EAP   + + +     G  A L+C + G P P I W +
Sbjct: 24151 IKTKLTSG--------------EAPGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYR 24196

Query: 1090  NKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVKVIAQ 1148
                 ++   +Y+M S+    TL +      D G Y C A N++G VE   KL ++   Q
Sbjct: 24197 FGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQATPQ 24255



 Score =  111 bits (277), Expect = 4e-24
 Identities = 171/794 (21%), Positives = 305/794 (38%), Gaps = 96/794 (12%)

Query: 381   GERVELECEVSEDDA-NVKWFKNGEEIIPGPKSRYRIRVEGKKHI--LIIEGATKADAAE 437
             G  V+L   +S   A  ++W+K+ +E+    ++   + VE    +  ++I+ A + ++  
Sbjct: 20515 GTSVKLRAGISGKPAPTIEWYKDDKEL----QTNALVCVENTTDLASILIKDADRLNSGC 20570

Query: 438   YSVMTTGGQSSAKLSVDL----KPLKILTPLTDQTVNLGKEICLKCEISENIPGKWTKNG 493
             Y +       SA  ++ +    KP     P+  +TV   K   L    +++   K T   
Sbjct: 20571 YELKLRNAMGSASATIRVQILDKPGPPGGPIEFKTVTAEKITLLWRPPADDGGAKITHYI 20630

Query: 494   LPVQESDRLK-VVHKGRIHKLVIANALTEDEGDYVF---APDAYNVTLPAKVH-VIDPPK 548
             +  +E+ R+   +    + + +I         +Y+F   A + Y +  P +   V+    
Sbjct: 20631 VEKRETSRVVWSMVSEHLEECIITTTKIIKGNEYIFRVRAVNKYGIGEPLESDSVVAKNA 20690

Query: 549   IILDGLDADNTVTVIAGNKLRL----EIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYP 604
              +  G      VT I  N + +     I   G         + DK  + G  ++  E+  
Sbjct: 20691 FVTPGPPGIPEVTKITKNSMTVVWSRPIADGGSDISGYFLEKRDKKSL-GWFKVLKETIR 20749

Query: 605   DSSTLVIDIAERDDSGVYHINLKNEAGE---AHASIKVKVVDFPDPPVAPTVTEVGDDW- 660
             D+   V  + E  D   Y +   N AG+   +  S   K  D  DPP  P    + D   
Sbjct: 20750 DTRQKVTGLTENSDYQ-YRVCAVNAAGQGPFSEPSEFYKAADPIDPPGPPAKIRIADSTK 20808

Query: 661   --CIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNF-DLCKETTFEPKKMIEGVAYEV 717
                 + W  P YDGGS + GY +E ++ +   W  ++     + T +    +  GV Y  
Sbjct: 20809 SSITLGWSKPVYDGGSAVTGYVVEIRQGEEEEWTTVSTKGEVRTTEYVVSNLKPGVNYYF 20868

Query: 718   RIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGY 777
             R+ AVN  G  +P   + P     +   P +       D  V +R      I  AG D  
Sbjct: 20869 RVSAVNCAGQGEPIEMNEPVQAKDILEAPEI-------DLDVALR---TSVIAKAGEDVQ 20918

Query: 778   VLEYCFEG----TEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVN-----------A 822
             VL   F+G    T  W    K+L    +++I    TD+   + +  V             
Sbjct: 20919 VL-IPFKGRPPPTVTWRKDEKNLGSDARYSIEN--TDSSSLLTIPQVTRNDTGKYILTIE 20975

Query: 823   AGASEPKYYSQPILVKEIIEP---PKIRIPRHLKQTYIRRVGE---------AVNLVIPF 870
              G  EPK  S  + VK +  P    K+++ +H+ +  +  + +          +N VI  
Sbjct: 20976 NGVGEPK--SSTVSVKVLDTPAACQKLQV-KHVSRGTVTLLWDPPLIDGGSPIINYVI-- 21030

Query: 871   QGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETAS 930
             + +   + TW     +       + +    T  F R    +  G       + +  ET  
Sbjct: 21031 EKRDATKRTWSVVSHKCSSTSFKLIDLSEKTPFFFRVLAENEIG-------IGEPCETTE 21083

Query: 931   IDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIE 990
               ++  + P P + + ++D    +V L+WT P  DG + IT Y +++  K    W +   
Sbjct: 21084 -PVKAAEVPAPIRDLSMKDSTKTSVILSWTKPDFDGGSVITEYVVERKGKGEQTW-SHAG 21141

Query: 991   HYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDF 1050
                     +++L   +   FRVF++N  GLS+  T+          G I    V E    
Sbjct: 21142 ISKTCEIEVSQLKEQSVLEFRVFAKNEKGLSDPVTI----------GPI---TVKELIIT 21188

Query: 1051  SEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCT 1110
              E  +   P        G+N  L    +G PKP I+W+K+ + + +    R    +   T
Sbjct: 21189 PEVDLSDIPGAQVTVRIGHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKIT 21248

Query: 1111  LEIRKPSPYDGGTY 1124
             L I+      GG Y
Sbjct: 21249 LSIKNAKKEHGGKY 21262



 Score =  110 bits (276), Expect = 6e-24
 Identities = 178/826 (21%), Positives = 314/826 (38%), Gaps = 118/826 (14%)

Query: 377   TAYCGERVELECEVS-EDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADA 435
             T   G  + L+  V  + +  + W K  +E+    K    ++  GK+   +I+   ++D+
Sbjct: 22686 TIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEK--VSLQYTGKRATAVIKFCDRSDS 22743

Query: 436   AEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCEISENIP-----GKWT 490
              +Y++       +  +SV +K L    P    TV+   +   KC ++ ++P      + T
Sbjct: 22744 GKYTLTVKNASGTKAVSVMVKVLDSPGPCGKLTVSRVTQE--KCTLAWSLPQEDGGAEIT 22801

Query: 491   KNGLPVQESDRLK-VVHKGRIHKLVIANALTEDEGDYVF---APDAYNVTLPAKVH---- 542
                +  +E+ RL  V+ +G    L           +Y+F   A + Y   +P +      
Sbjct: 22802 HYIVERRETSRLNWVIVEGECPTLSYVVTRLIKNNEYIFRVRAVNKYGPGVPVESEPIVA 22861

Query: 543   ----VIDPPKIILDGLDADNTVTVI--------AGNKLRLEIPISGEPPPKAMWSRGDKA 590
                  I  P  I + +       +I         GN++   + +         W+R +K 
Sbjct: 22862 RNSFTIPSPPGIPEEVGTGKEHIIIQWTKPESDGGNEISNYL-VDKREKKSLRWTRVNKD 22920

Query: 591   IMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDF-PDPPV 649
              +    R++  S  +       +   + +G       +E  EA   I  +   + P PP 
Sbjct: 22921 YVVYDTRLKVTSLMEGCDYQFRVTAVNAAG------NSEPSEASNFISCREPSYTPGPPS 22974

Query: 650   APTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLC-KETTFEPKK 708
             AP V +       + W  P YDGG+ I+GY +E ++K + +W R++ +   + T F    
Sbjct: 22975 APRVVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDTDQWYRVHTNATIRNTEFTVPD 23034

Query: 709   MIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTT---------- 758
             +  G  Y  R+ AVN  G+S+ S       P+     P L   D +  T           
Sbjct: 23035 LKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEIPDLELADDLKKTVTIRAGASLRL 23094

Query: 759   -VTMRWRPPDHI--GAAGLDGYVLEYCFEGTEDW---IVANKDLIDKTKFTITGLPTDAK 812
              V++  RPP  I     G+D        + TE +   IV   +  D  K+TI        
Sbjct: 23095 MVSVSGRPPPVITWSKQGID-LASRAIIDTTESYSLLIVDKVNRYDAGKYTI-------- 23145

Query: 813   IFVRVKAVNAAGASEPKYYSQPILVKEIIEP---PKIRIPRHLKQTY-----IRRV--GE 862
                  +A N +G       S  +LVK    P   P +++    + +      I  +  G 
Sbjct: 23146 -----EAENQSGKK-----SATVLVKVYDTPGPCPSVKVKEVSRDSVTITWEIPTIDGGA 23195

Query: 863   AVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKV 922
              VN  I  + +      +K    +  K    I      T+ + R    +  G       +
Sbjct: 23196 PVNNYI-VEKREAAMRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYG-------I 23247

Query: 923   DKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKS 982
              +  ET+   + + + P  P  +++ DV    V L W  P  DG + +TGY ++     +
Sbjct: 23248 GEPCETSDA-VLVSEVPLVPAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGT 23306

Query: 983   MEWF-------TVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIAR 1035
               W        TV+EH      T+T L  G +Y FR+ ++N  G+SE       +AV  +
Sbjct: 23307 ERWMKVVTLKPTVLEH------TVTSLNEGEQYLFRIRAQNEKGVSEPRETV--TAVTVQ 23358

Query: 1036  DGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIV 1095
             D ++         D S     T P    +  AG    L   + G P P  +W      + 
Sbjct: 23359 DLRVLPT-----IDLS-----TMPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLR 23408

Query: 1096  DDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKL 1141
             +  R  + ++  V  L IR+ +  D G Y  +  N  GT     K+
Sbjct: 23409 ESERVTVETHTKVAKLTIRETTIRDTGEYTLELKNVTGTTSETIKV 23454



 Score =  110 bits (275), Expect = 8e-24
 Identities = 93/366 (25%), Positives = 162/366 (44%), Gaps = 18/366 (4%)

Query: 294  RVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGD 353
            R  F  E+++P + V+W K+ QE++ + +   + +     L I + +M+D  +Y V AG 
Sbjct: 3028 RAMFECEVSEPDITVQWMKDDQELQITDRIKIQKEKYVHRLLIPSTRMSDAGKYTVVAGG 3087

Query: 354  EKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSR 413
               + +LFV    + +    ++      +R  +E EV+EDD +  W+K+G EI    + R
Sbjct: 3088 NVSTAKLFVEGRDVRIRSIKKEVQVIEKQRAVVEFEVNEDDVDAHWYKDGIEINFQVQER 3147

Query: 414  YRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDL-KPLKILTPLTDQTVNLG 472
            ++  VE + H + I    ++DA EY+ +    +SS  L V+  +P ++L  L   TV  G
Sbjct: 3148 HKYVVERRIHRMFISETRQSDAGEYTFVAGRNRSSVTLYVNAPEPPQVLQELQPVTVQSG 3207

Query: 473  KEICLKCEISENIPGK--WTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVF-A 529
            K       IS     K  W K    +    + K +H G+ + L++  A  ED   Y   A
Sbjct: 3208 KPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEA 3267

Query: 530  PDAYNVTLPAKVHVIDPPKIILDGLD-----------ADNTVTVIAGNKLRLEIPISGEP 578
             + Y V   +    ++ P+++    +             +TVT   G   R +  +SG  
Sbjct: 3268 KNDYGVATTSASLSVEVPEVVSPDQEMPVYPPAIITPLQDTVT-SEGQPARFQCRVSG-T 3325

Query: 579  PPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIK 638
              K  W   DK I + S   R   + D+  L I  A  +D G Y     N  G+  ++  
Sbjct: 3326 DLKVSWYSKDKKI-KPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTAN 3384

Query: 639  VKVVDF 644
            + +  F
Sbjct: 3385 LSLEGF 3390



 Score =  110 bits (275), Expect = 8e-24
 Identities = 108/438 (24%), Positives = 170/438 (38%), Gaps = 62/438 (14%)

Query: 727   ISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGT 786
             + KP +P+ P            +  D VT   +T++W PP   G + +  Y+LE      
Sbjct: 13701 VGKPGIPTGP------------IKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDSVN 13748

Query: 787   EDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGA-----SEPKYYSQPILVKEII 841
               W+      + KT F +T L    +   RV A N  G      SEP     P  V +  
Sbjct: 13749 NKWVTC-ASAVQKTTFRVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVPDAP 13807

Query: 842   EPPKIRIPRH----LKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNS 897
              PP I   RH    L  T  ++ G +       + K R  L WK+     +K  I +R+ 
Sbjct: 13808 PPPNIVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKR----ANKTPIRMRDF 13863

Query: 898   ETDTIIFIRKAERSHSGKYDLQVKVDKFVETAS--------IDIQIIDRPGPPQIVKIED 949
             +   +        +   +Y+ +V                  + +  ID PG P+++ I  
Sbjct: 13864 KVTGL--------TEGLEYEFRVMAINLAGVGKPSLPSEPVVALDPIDPPGKPEVINITR 13915

Query: 950   VWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIE-HYHRTSATITELVIGNEY 1008
                 +V L WT PK DG   +TGY ++K D  S  W      +    + T+T+LV G +Y
Sbjct: 13916 ---NSVTLIWTEPKYDGGHKLTGYIVEKRDLPSKSWMKANHVNVPECAFTVTDLVEGGKY 13972

Query: 1009  YFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAI-- 1066
              FR+ ++N  G     + + E+ +I +D            ++    +   P +       
Sbjct: 13973 EFRIRAKNTAGAISAPSESTET-IICKD------------EYEAPTIVLDPTIKDGLTIK 14019

Query: 1067  AGYNATLNC-SVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYC 1125
             AG    LN  S+ G P PK +W K    I      ++ S      L I+  +  D G Y 
Sbjct: 14020 AGDTIVLNAISILGKPLPKSSWSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGEYT 14079

Query: 1126  CKAVNDLGTVEIECKLEV 1143
               A N  GT     K+ V
Sbjct: 14080 ITATNPFGTKVEHVKVTV 14097



 Score =  109 bits (273), Expect = 1e-23
 Identities = 118/440 (26%), Positives = 185/440 (42%), Gaps = 69/440 (15%)

Query: 622   YHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFI 681
             Y +N    +  + AS  +   +  D P  P VT+V      + W  PAYDGGS ++GY I
Sbjct: 22544 YALNAAGVSKASEASRPIMAQNPVDAPGRPEVTDVTRSTVSLIWSAPAYDGGSKVVGYII 22603

Query: 682   ERK---KKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIG-ISKPSMPSRPF 737
             ERK   +    RW++ N+ +  +  F    + EG  YE R+ A NA G ISK S  + P 
Sbjct: 22604 ERKPVSEVGDGRWLKCNYTIVSDNFFTVTALSEGDTYEFRVLAKNAAGVISKGSESTGPV 22663

Query: 738   VPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTED----WIVAN 793
                   +PP       +    VT+R         AG D  VL+    G  +    W   +
Sbjct: 22664 TCRDEYAPPKAELDARLHGDLVTIR---------AGSD-LVLDAAVGGKPEPKIIWTKGD 22713

Query: 794   K--DLIDKTKFTITGLPTDAKIFVRVKA------VNAAGASEPKYYSQPILVKEIIEPPK 845
             K  DL +K     TG    A I    ++      +    AS  K  S  ++VK +  P  
Sbjct: 22714 KELDLCEKVSLQYTGKRATAVIKFCDRSDSGKYTLTVKNASGTKAVS--VMVKVLDSP-- 22769

Query: 846   IRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTW----KKDGAEI--------DKNQIN 893
                            G    L +    + +  L W    +  GAEI        + +++N
Sbjct: 22770 ---------------GPCGKLTVSRVTQEKCTLAWSLPQEDGGAEITHYIVERRETSRLN 22814

Query: 894   --IRNSETDTIIFIRKAERSHSGKYDLQVK-VDKFVETASIDIQ-IIDR-----PGPPQI 944
               I   E  T+ ++       + +Y  +V+ V+K+     ++ + I+ R     P PP I
Sbjct: 22815 WVIVEGECPTLSYV-VTRLIKNNEYIFRVRAVNKYGPGVPVESEPIVARNSFTIPSPPGI 22873

Query: 945   VKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHY--HRTSATITEL 1002
              +      E++ + WT P+ DG   I+ Y + K +KKS+ W  V + Y  + T   +T L
Sbjct: 22874 PEEVGTGKEHIIIQWTKPESDGGNEISNYLVDKREKKSLRWTRVNKDYVVYDTRLKVTSL 22933

Query: 1003  VIGNEYYFRVFSENMCGLSE 1022
             + G +Y FRV + N  G SE
Sbjct: 22934 MEGCDYQFRVTAVNAAGNSE 22953



 Score =  107 bits (268), Expect = 5e-23
 Identities = 123/468 (26%), Positives = 198/468 (42%), Gaps = 56/468 (11%)

Query: 221  RREVKQQEEE---PQVDVWELLKNAKPSEYEKIAFQYGITDLRGMLKRLKRMRREEKKSA 277
            R + K++ EE     +   EL    K   YE++  +        +L   K +  EEKK+ 
Sbjct: 1952 RSKFKRRTEEGYYEAITAVELKSRKKDESYEELLRK----TKDELLHWTKELTEEEKKAL 2007

Query: 278  AF-AKILDPAYQVDK-----------------------GGRVRFVVELAD-PKLEVKWYK 312
            A   KI  P ++ DK                       G    F V +   P  E +WYK
Sbjct: 2008 AEEGKITIPTFKPDKIELSPSMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYK 2067

Query: 313  NGQEIRPSTK---YIFEHKGCQRILFINNCQMTDDSEYYV----TAGDEKCSTELFVREP 365
            NG +I  S +   Y  E   C+  L I +    D +   V     AG+      L V+  
Sbjct: 2068 NGVKIERSDRIYWYWPEDNVCE--LVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQAK 2125

Query: 366  PIMV-TKQLEDTTAYCGERV-ELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKH 423
             ++  T++L+D  A   + +   ECE SE    VKW+K+G E+  G K  YR+  + K H
Sbjct: 2126 QLITFTQELQDVVAKEKDTMATFECETSEPFVKVKWYKDGMEVHEGDK--YRMHSDRKVH 2183

Query: 424  ILIIEGATKADAAEYS---VMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCE 480
             L I     +DA +YS   V     +++AKL V+   ++ +  L D  V       L+C 
Sbjct: 2184 FLSILTIDTSDAEDYSCVLVEDENVKTTAKLIVEGAVVEFVKELQDIEVPESYSGELECI 2243

Query: 481  IS-ENIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPA 539
            +S ENI GKW  N + ++ + +  +  +     L + +   ED+G+Y F  D    T   
Sbjct: 2244 VSPENIEGKWYHNDVELKSNGKYTITSRRGRQNLTVKDVTKEDQGEYSFVIDGKKTT--C 2301

Query: 540  KVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIR 599
            K+ +   P  IL GL       V  G+ ++LE+ +S E   + +W + D   ++ S R+ 
Sbjct: 2302 KLKMKPRPIAILQGLSDQK---VCEGDIVQLEVKVSLE-SVEGVWMK-DGQEVQPSDRVH 2356

Query: 600  TESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDP 647
                  S  L+I+   ++D+G Y   +          + V  VD   P
Sbjct: 2357 IVIDKQSHMLLIEDMTKEDAGNYSFTIPALGLSTSGRVSVYSVDVITP 2404



 Score =  106 bits (265), Expect = 1e-22
 Identities = 127/538 (23%), Positives = 203/538 (37%), Gaps = 68/538 (12%)

Query: 645  PDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTF 704
            P PP  P V +       + W+PPA DGGSPI GY +E +++ ++ W R+N      TT 
Sbjct: 9333 PGPPSCPEVKDKTKSSISLGWKPPAKDGGSPIKGYIVEMQEEGTTDWKRVNEPDKLITTC 9392

Query: 705  E--PKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTV--- 759
            E     + E   Y  R+ AVN  G S+PS  +       +   P +       D  V   
Sbjct: 9393 ECVVPNLKELRKYRFRVKAVNEAGESEPSDTTGEIPATDIQEEPEVFIDIGAQDCLVCKA 9452

Query: 760  --------TMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDA 811
                     ++ RP     +   DG   +   +G  D I  +  L      ++  +P   
Sbjct: 9453 GSQIRIPAVIKGRPTPK-SSWEFDGKAKKAMKDGVHD-IPEDAQLETAENSSVIIIPECK 9510

Query: 812  KIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIP-- 869
            +      ++ A   +  K  +  + V ++  PPK      LK + I R    ++  +P  
Sbjct: 9511 RSHTGKYSITAKNKAGQKTANCRVKVMDVPGPPK-----DLKVSDITRGSCRLSWKMPDD 9565

Query: 870  ----------FQGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIR-KAERSHSGKYDL 918
                       + +      W K   +       + +  ++   F R +AE     ++ +
Sbjct: 9566 DGGDRIKGYVIEKRTIDGKAWTKVNPDCGSTTFVVPDLLSEQQYFFRVRAEN----RFGI 9621

Query: 919  QVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQ-- 976
               V+    T + D   I  P PP  +KI  +    V L+W PPK+DG + +T Y ++  
Sbjct: 9622 GPPVETIQRTTARDP--IYPPDPPIKLKIGLITKNTVHLSWKPPKNDGGSPVTHYIVECL 9679

Query: 977  ---KADKKSMEWFTVIEH-YHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAV 1032
                   K   W    +        T+ +LV G EY FRV + N  G+S+ +        
Sbjct: 9680 AWDPTGTKKEAWRQCNKRDVEELQFTVEDLVEGGEYEFRVKAVNAAGVSKPSATVGPCDC 9739

Query: 1033 IARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMK--- 1089
               D      P  +  +F E               G N  +   ++G P P +TW K   
Sbjct: 9740 QRPD----MPPSIDLKEFMEVE------------EGTNVNIVAKIKGVPFPTLTWFKAPP 9783

Query: 1090 ----NKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1143
                NK  ++ D           CTL I +    D G Y   AVN+LGT   E +L V
Sbjct: 9784 KKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDTGLYTITAVNNLGTASKEMRLNV 9841



 Score =  105 bits (263), Expect = 2e-22
 Identities = 101/375 (26%), Positives = 158/375 (42%), Gaps = 21/375 (5%)

Query: 288  QVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEY 347
            +V +G  V+  V+++   +E  W K+GQE++PS +          +L I +    D   Y
Sbjct: 2320 KVCEGDIVQLEVKVSLESVEGVWMKDGQEVQPSDRVHIVIDKQSHMLLIEDMTKEDAGNY 2379

Query: 348  YVTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDD-ANVKWFKNGEEI 406
              T      ST   V    + V   L+D     G +  LEC+VS  D  +VKW+ N E+I
Sbjct: 2380 SFTIPALGLSTSGRVSVYSVDVITPLKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQI 2439

Query: 407  IPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTD 466
               P  R +  V+G K  L+I     +D   Y ++    +++  LSV+   +KI+  L D
Sbjct: 2440 --KPDDRVQAIVKGTKQRLVINRTHASDEGPYKLIVGRVETNCNLSVE--KIKIIRGLRD 2495

Query: 467  QTVNLGKEICLKCEISEN-IPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGD 525
             T    + +  + E+S + I   W      ++ S + K+   G+I+KL + N + +DEG 
Sbjct: 2496 LTCTETQNVVFEVELSHSGIDVLWNFKDKEIKPSSKYKIEAHGKIYKLTVLNMMKDDEGK 2555

Query: 526  YVF--APDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAM 583
            Y F    +  +  L      I  P         D TV          E+     P  K  
Sbjct: 2556 YTFYAGENMTSGKLTVAGGAISKPL-------TDQTVAESQEAVFECEV---ANPDSKGE 2605

Query: 584  WSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVD 643
            W R  K  +  +  IR+ES      L+I   + DD G Y    K    +  A +KV+ V 
Sbjct: 2606 WLRDGKH-LPLTNNIRSESDGHKRRLIIAATKLDDIGEY--TYKVATSKTSAKLKVEAVK 2662

Query: 644  FPDPPVAPTVTEVGD 658
                    TVTE  D
Sbjct: 2663 IKKTLKNLTVTETQD 2677



 Score =  102 bits (255), Expect = 2e-21
 Identities = 103/389 (26%), Positives = 171/389 (43%), Gaps = 15/389 (3%)

Query: 273  EKKSAAFAKILDPAYQVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHK-GCQ 331
            E+    F K L+    V KG  +    EL + + +V W K+G+ +      I     G  
Sbjct: 4836 EELPVRFVKTLEEEVTVVKGQPLYLSCEL-NKERDVVWRKDGKIVVEKPGRIVPGVIGLM 4894

Query: 332  RILFINNCQMTDDSEYYVT---AGDEKCSTELFVREP-PIMVTKQLEDTTAYCGERVELE 387
            R L IN+   TD   Y VT   A + +CS+ + V E     + K + D            
Sbjct: 4895 RALTINDADDTDAGTYTVTVENANNLECSSCVKVVEVIRDWLVKPIRDQHVKPKGTAIFA 4954

Query: 388  CEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQS 447
            C++++D  N+KWFK  +EI   P  +  I  +G    L I+ A   D AEY+V   G + 
Sbjct: 4955 CDIAKDTPNIKWFKGYDEIPAEPNDKTEILRDGNHLYLKIKNAMPEDIAEYAVEIEGKRY 5014

Query: 448  SAKLSVDLKPLKILTPLTDQTVNLGKEICLKCEISE-NIPGKWTKNGLPVQESDRLKVVH 506
             AKL++  + +++L P+ D T+   +      EISE +IPG+W   G  ++ S   ++  
Sbjct: 5015 PAKLTLGEREVELLKPIEDVTIYEKESASFDAEISEADIPGQWKLKGELLRPSPTCEIKA 5074

Query: 507  KGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGN 566
            +G    L +     +  G+ ++   A N    A   ++   +I LD       VTV    
Sbjct: 5075 EGGKRFLTLHKVKLDQAGEVLY--QALNAITTA---ILTVKEIELDFAVPLKDVTVPERR 5129

Query: 567  KLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINL 626
            + R E  ++ E     +WS+G   I++ S +    +      LVI+ ++ DD GVY   +
Sbjct: 5130 QARFECVLTRE--ANVIWSKGPD-IIKSSDKFDIIADGKKHILVINDSQFDDEGVYTAEV 5186

Query: 627  KNEAGEAHASIKVKVVDFPDPPVAPTVTE 655
            + +   A   +    + F  P    TV E
Sbjct: 5187 EGKKTSARLFVTGIRLKFMSPLEDQTVKE 5215



 Score =  102 bits (254), Expect = 2e-21
 Identities = 85/281 (30%), Positives = 121/281 (43%), Gaps = 16/281 (5%)

Query: 308  VKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTELFVREPPI 367
            V W K    I+ S K+     G + IL IN+ Q  D+  Y      +K S  LFV    +
Sbjct: 5143 VIWSKGPDIIKSSDKFDIIADGKKHILVINDSQFDDEGVYTAEVEGKKTSARLFVTGIRL 5202

Query: 368  MVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILII 427
                 LED T   GE     CE+S +  +V WFKN  ++         I  EGK H L +
Sbjct: 5203 KFMSPLEDQTVKEGETATFVCELSHEKMHVVWFKNDAKL--HTSRTVLISSEGKTHKLEM 5260

Query: 428  EGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCEISENIPG 487
            +  T  D ++         S+A+L V          L D+T     EI LKCE+S+++P 
Sbjct: 5261 KEVTLDDISQIKAQVKELSSTAQLKVLEADPYFTVKLHDKTAVEKDEITLKCEVSKDVPV 5320

Query: 488  KWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYV----FAPDAYNVTLPAKVHV 543
            KW K+G  +  S +  +   G    L I  A  +D+G+YV          NVT+ A++  
Sbjct: 5321 KWFKDGEEIVPSPKYSIKADGLRRILKIKKADLKDKGEYVCDCGTDKTKANVTVEARLIK 5380

Query: 544  IDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMW 584
            ++ P   L G      V V  G     EI +S EP     W
Sbjct: 5381 VEKP---LYG------VEVFVGETAHFEIELS-EPDVHGQW 5411



 Score =  102 bits (254), Expect = 2e-21
 Identities = 174/746 (23%), Positives = 285/746 (38%), Gaps = 121/746 (16%)

Query: 365   PPIMVTKQLEDTTAYCGERVELECEV-SEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKH 423
             P I++ +Q+   T   G+++ +E  V  +     KW K  +E++    S   +       
Sbjct: 12528 PKILMPEQI---TIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTS--SHLAVHKADSSS 12582

Query: 424   ILIIEGATKADAAEYSVMT--TGGQSSAKLSV--------------------DLKPLKIL 461
             ILII+  T+ D+  YS+    + G  + K+ V                    D   L   
Sbjct: 12583 ILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPGPPQPPFDISDIDADACSLSWH 12642

Query: 462   TPLTDQTVNLGKEICLKCEISENIPGKW-TKNGLPVQESDRLKVVHKGRIH--------K 512
              PL D   N+   I  KC++S    G W T      + S R+  +  G+ +        +
Sbjct: 12643 IPLEDGGSNITNYIVEKCDVSR---GDWVTALASVTKTSCRVGKLIPGQEYIFRVRAENR 12699

Query: 513   LVIANALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKIIL--DGLDADNTVTVIAGNKLRL 570
               I+  LT  +    F     +    A+V  ++   I +  D  D+D    +I       
Sbjct: 12700 FGISEPLTSPKMVAQFPFGVPSEPKNARVTKVNKDCIFVAWDRPDSDGGSPIIG------ 12753

Query: 571   EIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEA 630
                I  +     +W + +  +      +R+  YP +   +++  E      + I   N+A
Sbjct: 12754 -YLIERKERNSLLWVKANDTL------VRSTEYPCAG--LVEGLEYS----FRIYALNKA 12800

Query: 631   GEAHASIKVKVVDFP---DPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQ 687
             G +  S   + V      DPP  P V +V      + W  P +DGGS I+GYF+E  K  
Sbjct: 12801 GSSPPSKPTEYVTARMPVDPPGKPEVIDVTKSTVSLIWARPKHDGGSKIIGYFVEACKLP 12860

Query: 688   SSRWMRLNF--DLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSP 745
               +W+R N       +  +    + E   Y+ R  A  A+ IS PS PS P   LA   P
Sbjct: 12861 GDKWVRCNTAPHQIPQEEYTATGLEEKAQYQFRAIARTAVNISPPSEPSDPVTILAENVP 12920

Query: 746   P---------TLLTVDSVT----DTTV------TMRWRPPDHI--GAAGLDGYVLEYCFE 784
             P         +LLTV + T    D TV      T+ W+    +   A G+    ++    
Sbjct: 12921 PRIDLSVAMKSLLTVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIK-MAMQRNLC 12979

Query: 785   GTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEP----KYYSQPILVKEI 840
               E + V  KD  D T  T           +++K ++  G        K YS   ++   
Sbjct: 12980 TLELFSVNRKDSGDYT-ITAENSSGSKSATIKLKVLDKPGPPASVKINKMYSDRAMLSW- 13037

Query: 841   IEPPKIRIPRHLKQTYIRRVG-EAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSET 899
              EPP            +   G E  N ++  +   RP   W +  A +     ++     
Sbjct: 13038 -EPP------------LEDGGSEITNYIVDKRETSRPN--WAQVSATVPITSCSVEKLIE 13082

Query: 900   DTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTW 959
                   R    +  G  D       F E A I     D PG      I ++  +++ ++W
Sbjct: 13083 GHEYQFRICAENKYGVGD-----PVFTEPA-IAKNPYDPPGRCDPPVISNITKDHMTVSW 13136

Query: 960   TPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATI--TELVIGNEYYFRVFSENM 1017
              PP DDG + ITGY ++K + +++ W T +        T+  T L  G EY FRV + N 
Sbjct: 13137 KPPADDGGSPITGYLLEKRETQAVNW-TKVNRKPIIERTLKATGLQEGTEYEFRVTAINK 13195

Query: 1018  CGLSEDATMTKESAVIARDGKIYKNP 1043
              G  + +  +K  A  ARD +    P
Sbjct: 13196 AGPGKPSDASK--AAYARDPQYPPGP 13219



 Score =  101 bits (251), Expect = 5e-21
 Identities = 123/553 (22%), Positives = 204/553 (36%), Gaps = 63/553 (11%)

Query: 622   YHINLKNEAGEAHASIKVKVV---DFPDPPVAPTVTEVGDDW---CIMNWEPPAYDGGSP 675
             + +  +NE G    S+  + V   D  +PP  PT   V D       + W  P YDGG+P
Sbjct: 12096 FRVKAENEIGIGEPSLPSRPVVAKDPIEPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAP 12155

Query: 676   ILGYFIERKKKQSSR-----WMRLNFDL-CKETTFEPKKMIEGVAYEVRIFAVNAIGISK 729
             I+GY +E + K +       W R N         F    + E   YE R+ A N +GI +
Sbjct: 12156 IIGYVVEMRPKIADASPDEGWKRCNAAAQLVRKEFTVTSLDENQEYEFRVCAQNQVGIGR 12215

Query: 730   PSMPSRPFVPLAVTSPPTLLTVDSVTDTTVT-----------MRWRPPDHIG--AAGLDG 776
             P+       P  +  PP +    S+    +            +R RP   +     G+D 
Sbjct: 12216 PAELKEAIKPKEILEPPEIDLDASMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDN 12275

Query: 777   YVLEYCFEGTEDW---IVANKDLIDKTKFTITGL-PTDAK-IFVRVKAVNAAGASEPKYY 831
              V +   +  +     ++ N    D  K+++T + P   K +FV V+ ++  G       
Sbjct: 12276 VVRKGQVDLVDTMAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFVNVRVLDTPG------- 12328

Query: 832   SQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQ 891
               P+   ++ +  K     H+        G +       + +     TW     E+ K  
Sbjct: 12329 --PVSDLKVSDVTKTSC--HVSWAPPENDGGSQVTHYIVEKREADRKTWSTVTPEVKKTS 12384

Query: 892   INIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVW 951
              ++ N       + R    +  G       V   V    +    +  P PP+ +++ ++ 
Sbjct: 12385 FHVTNLVPGNEYYFRVTAVNEYGP-----GVPTDVPKPVLASDPLSEPDPPRKLEVTEMT 12439

Query: 952   GENVALTWTPPKDDGNAAITGY-TIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYF 1010
               +  L W PP  DG A I GY T  + +++  + +T        S  +T L  G +Y F
Sbjct: 12440 KNSATLAWLPPLRDGGAKIDGYITSYREEEQPADRWTEYSVVKDLSLVVTGLKEGKKYKF 12499

Query: 1011  RVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYN 1070
             RV + N  G+S           + R+ +     VYE  +    P    P   T   AG  
Sbjct: 12500 RVAARNAVGVS-----------LPREAE----GVYEAKEQLLPPKILMPEQITIK-AGKK 12543

Query: 1071  ATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVN 1130
               +   V G P P   W K +  +V      +        L I+  +  D G Y   A N
Sbjct: 12544 LRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGYYSLTAEN 12603

Query: 1131  DLGTVEIECKLEV 1143
               GT   + K+ V
Sbjct: 12604 SSGTDTQKIKVVV 12616



 Score =  100 bits (249), Expect = 8e-21
 Identities = 93/398 (23%), Positives = 157/398 (39%), Gaps = 40/398 (10%)

Query: 753   SVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAK 812
             +VT   +T+ WRPP   G A +  Y++E        W + ++ L ++   T T +    +
Sbjct: 20605 TVTAEKITLLWRPPADDGGAKITHYIVEKRETSRVVWSMVSEHL-EECIITTTKIIKGNE 20663

Query: 813   IFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQT-------YIRRVGEAVN 865
                RV+AVN  G  EP      +     + P    IP   K T       + R + +  +
Sbjct: 20664 YIFRVRAVNKYGIGEPLESDSVVAKNAFVTPGPPGIPEVTKITKNSMTVVWSRPIADGGS 20723

Query: 866   LVIPF--QGKPRPELTW---KKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQV 920
              +  +  + + +  L W    K+     + ++      +D    +     +  G +    
Sbjct: 20724 DISGYFLEKRDKKSLGWFKVLKETIRDTRQKVTGLTENSDYQYRVCAVNAAGQGPFS--- 20780

Query: 921   KVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADK 980
             +  +F + A      ID PGPP  ++I D    ++ L W+ P  DG +A+TGY ++    
Sbjct: 20781 EPSEFYKAADP----IDPPGPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVVEIRQG 20836

Query: 981   KSMEWFTVIE--HYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGK 1038
             +  EW TV        T   ++ L  G  YYFRV + N  G  E   M            
Sbjct: 20837 EEEEWTTVSTKGEVRTTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEM------------ 20884

Query: 1039  IYKNPVYEDFDFSEAPMFTQPLV---NTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIV 1095
                N   +  D  EAP     +    +  A AG +  +    +G P P +TW K++  + 
Sbjct: 20885 ---NEPVQAKDILEAPEIDLDVALRTSVIAKAGEDVQVLIPFKGRPPPTVTWRKDEKNLG 20941

Query: 1096  DDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLG 1133
              D RY + +      L I + +  D G Y     N +G
Sbjct: 20942 SDARYSIENTDSSSLLTIPQVTRNDTGKYILTIENGVG 20979



 Score = 98.6 bits (244), Expect = 3e-20
 Identities = 93/361 (25%), Positives = 149/361 (41%), Gaps = 12/361 (3%)

Query: 296  RFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEK 355
            +F  E++      +W K  QEI    ++     G +  + I +    D+++Y   A D+ 
Sbjct: 5486 KFECEVSREPKTFRWLKGTQEITGDDRFELIKDGTKHSMVIKSAAFEDEAKYMFEAEDKH 5545

Query: 356  CSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYR 415
             S +L +    +     L+D TA   E      E+S D+  VKWFKN + +         
Sbjct: 5546 TSGKLIIEGIRLKFLTPLKDVTAKEKESAVFTVELSHDNIRVKWFKNDQRL--HTTRSVS 5603

Query: 416  IRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEI 475
            ++ EGK H +  +  +  D ++  V   G  S AKL+V          L D T     E+
Sbjct: 5604 MQDEGKTHSITFKDLSIDDTSQIRVEAMGMSSEAKLTVLEGDPYFTGKLQDYTGVEKDEV 5663

Query: 476  CLKCEISE-NIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYN 534
             L+CEIS+ + P KW K+G  ++ S    +   G+   L++  AL  D G Y    D   
Sbjct: 5664 ILQCEISKADAPVKWFKDGKEIKPSKNAVIKADGKKRMLILKKALKSDIGQYTC--DCGT 5721

Query: 535  VTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWS-RGDKAIME 593
                 K+ + D    ++  L   ++V V+     R E  IS E    A W  +G+  +  
Sbjct: 5722 DKTSGKLDIEDREIKLVRPL---HSVEVMETETARFETEIS-EDDIHANWKLKGEALLQT 5777

Query: 594  GSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTV 653
                I+ E    S  LV+     D +G       N    AH  +K +V+    P    TV
Sbjct: 5778 PDCEIKEEGKIHS--LVLHNCRLDQTGGVDFQAANVKSSAHLRVKPRVIGLLRPLKDVTV 5835

Query: 654  T 654
            T
Sbjct: 5836 T 5836



 Score = 95.5 bits (236), Expect = 3e-19
 Identities = 111/492 (22%), Positives = 196/492 (39%), Gaps = 52/492 (10%)

Query: 673   GSPILGYFIERKKKQSSRWMRLNFDLCKET-TFEPKKMIEGVAYEVRIFAVNAIGISKPS 731
             G P+    + R        MR N ++  E  T   K+ +   A    I A N+ G +K  
Sbjct: 20130 GKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADAGRYEITAANSSGTTKAF 20189

Query: 732   MPSRPFVPLAVTSPPT-LLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWI 790
             +     V L    PPT  + +  +T+ +VT++W PP + G + +  Y+L      T  W 
Sbjct: 20190 IN---IVVLDRPGPPTGPVVISDITEESVTLKWEPPKYDGGSQVTNYILLKRETSTAVWT 20246

Query: 791   VANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVK---EIIEPPKIR 847
               +   + +T   +  L T  +   R+KA N  G S+    S  + VK       PP   
Sbjct: 20247 EVSAT-VARTMMKVMKLTTGEEYQFRIKAENRFGISD-HIDSACVTVKLPYTTPGPPSTP 20304

Query: 848   IPRHLKQTYI-----RRVGEAVNLVIPF--QGKPRPELTWKKDGAEIDKNQINIRNSETD 900
                ++ +  I       V    + V+ +  + K R  + W+K       N++ IR +   
Sbjct: 20305 WVTNVTRESITVGWHEPVSNGGSAVVGYHLEMKDRNSILWQK------ANKLVIRTTH-- 20356

Query: 901   TIIFIRKAERSHSGKYDLQVKVDKFVETA-----SIDIQIIDRPGPPQIVKIEDVWGENV 955
                  +    S    Y+ +V  +           S  +  ID   PP+ V+I D+   +V
Sbjct: 20357 ----FKVTTISAGLIYEFRVYAENAAGVGKPSHPSEPVLAIDACEPPRNVRITDISKNSV 20412

Query: 956   ALTWTPPKDDGNAAITGYTIQKADKKSMEWFTV-IEHYHRTSATITELVIGNEYYFRVFS 1014
             +L+W  P  DG + ITGY +++ D     W      +   T   I+ L   ++Y FRVF+
Sbjct: 20413 SLSWQQPAFDGGSKITGYIVERRDLPDGRWTKASFTNVTETQFIISGLTQNSQYEFRVFA 20472

Query: 1015  ENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAI---AGYNA 1071
              N  G     +++  S V+         P+    D    P+   PL  T  +   AG + 
Sbjct: 20473 RNAVG-----SISNPSEVVG--------PI-TCIDSYGGPVIDLPLEYTEVVKYRAGTSV 20518

Query: 1072  TLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVND 1131
              L   + G P P I W K+   +  +    + +   + ++ I+     + G Y  K  N 
Sbjct: 20519 KLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLASILIKDADRLNSGCYELKLRNA 20578

Query: 1132  LGTVEIECKLEV 1143
             +G+     ++++
Sbjct: 20579 MGSASATIRVQI 20590



 Score = 94.4 bits (233), Expect = 6e-19
 Identities = 105/462 (22%), Positives = 179/462 (38%), Gaps = 52/462 (11%)

Query: 697   DLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTD 756
             D C+E        +   A E  I  +N I + KP  P+ P            + +D VT 
Sbjct: 15837 DACREDVGHYVVKLTNSAGEA-IETLNVIVLDKPGPPTGP------------VKMDEVTA 15883

Query: 757   TTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVR 816
              ++T+ W PP + G + ++ Y++E     T  W + +   + +T      L T  +   R
Sbjct: 15884 DSITLSWGPPKYDGGSSINNYIVEKRDTSTTTWQIVSAT-VARTTIKACRLKTGCEYQFR 15942

Query: 817   VKAVNAAGAS-----EPKYYSQPILVKEIIEPPKIRIPRH--LKQTYIRRVGEAVNLVIP 869
             + A N  G S     EP     P  V      P + +     ++  +   + +  + VI 
Sbjct: 15943 IAAENRYGKSTYLNSEPTVAQYPFKVPGPPGTPVVTLSSRDSMEVQWNEPISDGGSRVIG 16002

Query: 870   F--QGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVE 927
             +  + K R  + W K    ++K  I     +T  +    + E   S +  + +     V 
Sbjct: 16003 YHLERKERNSILWVK----LNKTPIPQTKFKTTGLEEGVEYEFRVSAENIVGIGKPSKVS 16058

Query: 928   TASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFT 987
                +     D PG P+ + +      +V L W  P  DG + ITGY ++K +     W  
Sbjct: 16059 ECYVARDPCDPPGRPEAIIVTR---NSVTLQWKKPTYDGGSKITGYIVEKKELPEGRWMK 16115

Query: 988   V-IEHYHRTSATITELVIGNEYYFRVFSENMCGL-SEDATMTKESAVIARDG----KIYK 1041
                 +   T   +T LV  + Y FRV + N  G+ SE +  T   A+ ARD     +I  
Sbjct: 16116 ASFTNIIDTHFEVTGLVEDHRYEFRVIARNAAGVFSEPSEST--GAITARDEVDPPRISM 16173

Query: 1042  NPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYR 1101
             +P Y+D                   AG +  ++  + G P P I W+K    + +  R  
Sbjct: 16174 DPKYKD--------------TIVVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTARLE 16219

Query: 1102  MFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1143
             + S     +L ++     D G Y  KA N  G   +   ++V
Sbjct: 16220 IKSTDFATSLSVKDAVRVDSGNYILKAKNVAGERSVTVNVKV 16261



 Score = 94.4 bits (233), Expect = 6e-19
 Identities = 148/652 (22%), Positives = 260/652 (39%), Gaps = 111/652 (17%)

Query: 51    SRALERKDSDWTLVE---TPPGEEQAKQNANSQLSILFIEKPQGGTVKVGEDITFIAKVK 107
             S+  E K SD    E   T   E +A +  +S+  I  +   Q  TV       F  K  
Sbjct: 26447 SKISETKKSDQKTTESTVTRKTEPKAPEPISSKPVI--VTGLQDTTVSSDSVAKFAVKAT 26504

Query: 108   AEDLLRKPTIKWFK--------GKWMDLASKAGKHLQLKETFERHSRVYTFEMQIIKAKD 159
              E    +PT  W K        GK+     K G  L++ +T    S +YT  ++      
Sbjct: 26505 GEP---RPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVK------ 26555

Query: 160   NFAGNYR--CEVTYKDKFDSCSFDLEVHESTGTTPNIDIRSAFKRSGEGQEDAGELDFSG 217
             N AG+    C++T K   D+ +  +   +++  TP        K++   +E + +   S 
Sbjct: 26556 NSAGSVSSSCKLTIKAIKDTEAQKVSTQKTSEITPQ-------KKAVVQEEISQKALRSE 26608

Query: 218   LLKRREVKQQE------EEPQVDVWELLKNAKPSEYEKIAFQYGITDLRGMLKRLKRMRR 271
              +K  E K QE      E  +V + E +K +  +  EK      IT              
Sbjct: 26609 EIKMSEAKSQEKLALKEEASKVLISEEVKKSAATSLEKSIVHEEITKTS--------QAS 26660

Query: 272   EEKKSAAFAKILDPAYQVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQ 331
             EE ++ A  K       +++G R+     +A    +VKW  NG E+  S +Y +   G  
Sbjct: 26661 EEVRTHAEIKAFSTQMSINEGQRLVLKANIAGAT-DVKWVLNGVELTNSEEYRYGVSGSD 26719

Query: 332   RILFINNCQMTDDSEYYVTA----GDEKCSTELFVREPPIMVTKQLEDTTAYC------- 380
             + L I      D+      +    G  KC  +L        ++K+L D  A+        
Sbjct: 26720 QTLTIKQASHRDEGILTCISKTKEGIVKCQYDL-------TLSKELSDAPAFISQPRSQN 26772

Query: 381   ---GERVELECEVS-EDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAA 436
                G+ V   CE+S E    ++WFKN   I     S   I      + L I  A+ +D+ 
Sbjct: 26773 INEGQNVLFTCEISGEPSPEIEWFKNNLPI--SISSNVSISRSRNVYSLEIRNASVSDSG 26830

Query: 437   EYSVMTTG--GQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCEISENIPGKWTKNGL 494
             +Y++      GQ SA  S+      ++ PL ++     +E+ L+     ++ G ++   +
Sbjct: 26831 KYTIKAKNFRGQCSATASL------MVLPLVEEP---SREVVLRTSGDTSLQGSFSSQSV 26881

Query: 495   PVQESDR-----------LKVVHKGRIHKLVIANALTEDEGDYVFAPDAY----NVT--- 536
              +  S +              + + +   +   +  +  E     +  ++    N+T   
Sbjct: 26882 QMSASKQEASFSSFSSSSASSMTEMKFASMSAQSMSSMQESFVEMSSSSFMGISNMTQLE 26941

Query: 537   ------LPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKA 590
                   L A +  I PPKI  + L +D  +++  G  L +    +GEP P+  WS G + 
Sbjct: 26942 SSTSKMLKAGIRGI-PPKI--EALPSD--ISIDEGKVLTVACAFTGEPTPEVTWSCGGRK 26996

Query: 591   I-MEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKV 641
             I  +  GR   E+  D +TL+I   ++ D G+Y ++L NE G   A++ + +
Sbjct: 26997 IHSQEQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHI 27048



 Score = 93.2 bits (230), Expect = 1e-18
 Identities = 201/953 (21%), Positives = 329/953 (34%), Gaps = 190/953 (19%)

Query: 284   DPAYQVDKGGRVRFVVEL-ADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMT 342
             D  Y   +    R  + +   P   V W K    +   T+   E       L + +CQ +
Sbjct: 13617 DLCYLAKENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKS 13676

Query: 343   DDSEYYVT----AGDEKCSTELFVREPPIMVTKQL--EDTTAYC------------GERV 384
             D  +Y +T    AG ++ +  + V   P + T  +  ++ TA              G  +
Sbjct: 13677 DAGKYTITLKNVAGTKEGTISIKVVGKPGIPTGPIKFDEVTAEAMTLKWAPPKDDGGSEI 13736

Query: 385   ELECEVSEDDANVKWFKNGEEIIPGPKSRYRI-----------RVEGKKHILIIEGATKA 433
                     D  N KW      +    K+ +R+           RV  +    + EG    
Sbjct: 13737 TNYILEKRDSVNNKWVTCASAV---QKTTFRVTRLHEGMEYTFRVSAENKYGVGEGLKSE 13793

Query: 434   DAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEIC-LKCEISENIPGKWTK- 491
                                VD++   +    TD     G  I     E  E     W + 
Sbjct: 13794 PIVARHPFDVPDAPPPPNIVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRA 13853

Query: 492   NGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKIIL 551
             N  P++  D  KV              LTE   +Y F   A N+    K  +   P + L
Sbjct: 13854 NKTPIRMRD-FKVT------------GLTEGL-EYEFRVMAINLAGVGKPSLPSEPVVAL 13899

Query: 552   DGLDAD----------NTVTVI-------AGNKLRLEIPISGEPPPKAMWSRGDKAIMEG 594
             D +D            N+VT+I        G+KL   I    + P K+ W + +      
Sbjct: 13900 DPIDPPGKPEVINITRNSVTLIWTEPKYDGGHKLTGYIVEKRDLPSKS-WMKANHV---- 13954

Query: 595   SGRIRTESYPDSSTLVIDIAERDDSGVYH--INLKNEAGEAHA-SIKVKVVDFPDPPVAP 651
                    + P+ +  V D+ E    G Y   I  KN AG   A S   + +   D   AP
Sbjct: 13955 -------NVPECAFTVTDLVE---GGKYEFRIRAKNTAGAISAPSESTETIICKDEYEAP 14004

Query: 652   TVTEVGDDWCIMNWEPPAYDG-----GSPIL--GYFIERKKKQSSRWMRLNFDL----CK 700
             T+            +P   DG     G  I+     I  K    S W +   D+      
Sbjct: 14005 TIV----------LDPTIKDGLTIKAGDTIVLNAISILGKPLPKSSWSKAGKDIRPSDIT 14054

Query: 701   ETTFEPKKMIEGVAYEVR-------IFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDS 753
             + T  P   +  + Y  R       I A N  G     +       L V  PP  + + +
Sbjct: 14055 QITSTPTSSMLTIKYATRKDAGEYTITATNPFGTKVEHVK---VTVLDVPGPPGPVEISN 14111

Query: 754   VTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKI 813
             V+    T+ W PP   G + +  Y+LE        W V ++D I   +   T L    + 
Sbjct: 14112 VSAEKATLTWTPPLEDGGSPIKSYILEKRETSRLLWTVVSED-IQSCRHVATKLIQGNEY 14170

Query: 814   FVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGK 873
               RV AVN  G  EP   S+P+ + +   PP                G      +    K
Sbjct: 14171 IFRVSAVNHYGKGEP-VQSEPVKMVDRFGPP----------------GPPEKPEVSNVTK 14213

Query: 874   PRPELTWKKD----GAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETA 929
                 ++WK+     G+EI    +  R  E  ++ ++R  +   S   DL+ KV    E +
Sbjct: 14214 NTATVSWKRPVDDGGSEITGYHVERR--EKKSLRWVRAIKTPVS---DLRCKVTGLQEGS 14268

Query: 930   SIDIQIIDR-----------------------PGPPQIVKIEDVWGENVALTWTPPKDDG 966
             + + ++                          PGPP    + D   ++ +L W  P  DG
Sbjct: 14269 TYEFRVSAENRAGIGPPSEASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLAWGKPHYDG 14328

Query: 967   NAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGN-----EYYFRVFSENMCGLS 1021
                ITGY ++        W   I+    T+  IT+ V+ +     +Y FR+ + N  G+ 
Sbjct: 14329 GLEITGYVVEHQKVGDEAW---IKDTTGTALRITQFVVPDLQTKEKYNFRISAINDAGVG 14385

Query: 1022  EDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAI-AGYNATLNCSVRGN 1080
             E A +         D +I +  +  DF+          L  T  + AG +  +   ++G 
Sbjct: 14386 EPAVIP--------DVEIVEREMAPDFELDAE------LRRTLVVRAGLSIRIFVPIKGR 14431

Query: 1081  PKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLG 1133
             P P++TW K+ + + +  R  + + +    L I + + YD G +     N  G
Sbjct: 14432 PAPEVTWTKDNINLKN--RANIENTESFTLLIIPECNRYDTGKFVMTIENPAG 14482



 Score = 93.2 bits (230), Expect = 1e-18
 Identities = 127/584 (21%), Positives = 221/584 (37%), Gaps = 94/584 (16%)

Query: 606   SSTLVIDIAERDDSGV--YHINLKNEAGEAH----ASIKVKV------VDFPDPPVAPTV 653
             S T  I++++  +  V  + +  KNE G +       I VK       VD  D P A   
Sbjct: 21143 SKTCEIEVSQLKEQSVLEFRVFAKNEKGLSDPVTIGPITVKELIITPEVDLSDIPGAQVT 21202

Query: 654   TEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKET-TFEPKKMIEG 712
               +G +   ++ E P      P + +  +    + S ++R +    K T + +  K   G
Sbjct: 21203 VRIGHN---VHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHG 21259

Query: 713   VAYEVRI--------FAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWR 764
               Y V +          +  I +  PS P  P            +  D +   +V + W 
Sbjct: 21260 GKYTVILDNAVCRIAVPITVITLGPPSKPKGP------------IRFDEIKADSVILSWD 21307

Query: 765   PPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAG 824
              P+  G   +  Y +E       +W +     + +T F +  L  DA+   RV+A N  G
Sbjct: 21308 VPEDNGGGEITCYSIEKRETSQTNWKMVCSS-VARTTFKVPNLVKDAEYQFRVRAENRYG 21366

Query: 825   ASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKD- 883
              S      QP++   I+   + RIP           G+ V   +   G     LTW    
Sbjct: 21367 VS------QPLVSSIIVAKHQFRIPGP--------PGKPVIYNVTSDGM---SLTWDAPV 21409

Query: 884   ---GAEIDKNQINIRNSETDTIIFIRKAERSHSGK------------YDLQVKVDKFVET 928
                G+E+     ++   E ++I++ +      SG+            Y  +V  +     
Sbjct: 21410 YDGGSEV--TGFHVEKKERNSILWQKVNTSPISGREYRATGLVEGLDYQFRVYAENSAGL 21467

Query: 929   AS--------IDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADK 980
             +S        + +  +D PG P  +   DV  E + L W PP  DG + I GY+I+K   
Sbjct: 21468 SSPSDPSKFTLAVSPVDPPGTPDYI---DVTRETITLKWNPPLRDGGSKIVGYSIEKRQG 21524

Query: 981   KSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIY 1040
                              T+T L  G+ Y FR+ + N  G     + +    ++ RD  + 
Sbjct: 21525 NERWVRCNFTDVSECQYTVTGLSPGDRYEFRIIARNAVGTISPPSQSS-GIIMTRDENV- 21582

Query: 1041  KNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRY 1100
               P   +F     P +   L+     +G +  +   V+G P P++TW K+ V I      
Sbjct: 21583 --PPIVEF----GPEYFDGLIIK---SGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNM 21633

Query: 1101  RMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVK 1144
              +    G  +L +R  +    G Y  +A N  G+ + E K++V+
Sbjct: 21634 EITDVLGSTSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQ 21677



 Score = 92.8 bits (229), Expect = 2e-18
 Identities = 113/454 (24%), Positives = 172/454 (37%), Gaps = 74/454 (16%)

Query: 718   RIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGY 777
             R  AVN   + KP  P+ P            L ++ +T    ++ W  P   G A +D Y
Sbjct: 19499 RSVAVNCKVLDKPGPPAGP------------LEINGLTAEKCSLSWGRPQEDGGADIDYY 19546

Query: 778   VLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILV 837
             ++E        W +   +L   T   +T L    +   RV  VN  G  EP    + + +
Sbjct: 19547 IVEKRETSHLAWTICEGEL-QMTSCKVTKLLKGNEYIFRVTGVNKYGVGEPL---ESVAI 19602

Query: 838   KEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNS 897
             K +        P  L+ T + +  E++ L        RPE      G+EI    I  R  
Sbjct: 19603 KALDPFTVPSPPTSLEITSVTK--ESMTLCWS-----RPE---SDGGSEISGYIIERR-- 19650

Query: 898   ETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQI---------------------- 935
             E +++ ++R  ++     YDL+VK     E    + ++                      
Sbjct: 19651 EKNSLRWVRVNKKP---VYDLRVKSTGLREGCEYEYRVYAENAAGLSLPSETSPLIRAED 19707

Query: 936   -IDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHR 994
              +  P PP   KI D     + + W  P  DG A ITGYT++       +W T I+    
Sbjct: 19708 PVFLPSPPSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEYKKSDDTDWKTSIQSLRG 19767

Query: 995   TSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAP 1054
             T  TI+ L  G EY FRV S N  G S+ +  +        D +I K    E     ++ 
Sbjct: 19768 TEYTISGLTTGAEYVFRVKSVNKVGASDPSDSS--------DPQIAKEREEEPLFDIDSE 19819

Query: 1055  MFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMF--SNQGVCTLE 1112
             M    +V     AG + T+    RG P P + W K       D R R +  +     +L 
Sbjct: 19820 MRKTLIVK----AGASFTMTVPFRGRPVPNVLWSKPDT----DLRTRAYVDTTDSRTSLT 19871

Query: 1113  IRKPSPYDGGTYCCKAVNDLGTVEIECKLEVKVI 1146
             I   +  D G Y     N L    +   L VKV+
Sbjct: 19872 IENANRNDSGKYTLTIQNVLSAASL--TLVVKVL 19903



 Score = 92.4 bits (228), Expect = 2e-18
 Identities = 133/609 (21%), Positives = 230/609 (37%), Gaps = 111/609 (18%)

Query: 584  WSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVD 643
            WSR +K+++    +   +   +  T V  +   + +G    +  ++   AH  I      
Sbjct: 8576 WSRVNKSLLNAL-KANVDGLLEGLTYVFRVCAENAAGPGKFSPPSDPKTAHDPISP---- 8630

Query: 644  FPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETT 703
             P PP+ P VT+       + WEPPA++GG  I+GYF++++   ++ W R    + K   
Sbjct: 8631 -PGPPI-PRVTDTSSTTIELEWEPPAFNGGGEIVGYFVDKQLVGTNEWSRCTEKMIKVRQ 8688

Query: 704  FEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRW 763
            +  K++ EG  Y++R+ AVNA G   P        P+ V  P                  
Sbjct: 8689 YTVKEIREGADYKLRVSAVNAAGEGPPGETQ----PVTVAEPQ----------------- 8727

Query: 764  RPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAA 823
             PP    A  LD  V      G +  I+A K L  +    +TG P   K++ +       
Sbjct: 8728 EPP----AVELDVSVKG----GIQ--IMAGKTL--RIPAVVTGRPVPTKVWTK------- 8768

Query: 824  GASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLV--------IPFQGKPR 875
               E +     +++  +    ++ I   L++ + R V  A N          +     P 
Sbjct: 8769 --EEGELDKDRVVIDNVGTKSELIIKDALRKDHGRYVITATNSCGSKFAAARVEVFDVPG 8826

Query: 876  PELTWKKDGAEIDKNQINIRNSETDT------IIFIRKAERSHSGKYDLQVKVDKFVETA 929
            P L  K          +N  + E D        I  RK  + H+ +  ++ +  K   T 
Sbjct: 8827 PVLDLKPVVTNRKMCLLNWSDPEDDGGSEITGFIIERKDAKMHTWRQPIETERSKCDITG 8886

Query: 930  SID------------------------IQIIDRPGPP---QIVKIEDVWGENVALTWTPP 962
             ++                        I  +D  GPP   + +   +     + L W  P
Sbjct: 8887 LLEGQEYKFRVIAKNKFGCGPPVEIGPILAVDPLGPPTSPERLTYTERTKSTITLDWKEP 8946

Query: 963  KDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYY-FRVFSENMCGLS 1021
            + +G + I GY I+K      ++  V +    T++ + E +  ++ Y FRV + N  G S
Sbjct: 8947 RSNGGSPIQGYIIEKRRHDKPDFERVNKRLCPTTSFLVENLDEHQMYEFRVKAVNEIGES 9006

Query: 1022 EDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAI-AGYNATLNCSVRGN 1080
            E +       V+ +D ++               +      +T  + AG    +   V G 
Sbjct: 9007 EPSLPLN---VVIQDDEVPPT----------IKLRLSVRGDTIKVKAGEPVHIPADVTGL 9053

Query: 1081 PKPKITWMKNKVAI------VDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGT 1134
            P PKI W KN+  I      +   +  +  ++    L I K    D GTY   A N LG+
Sbjct: 9054 PMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAVREDKGTYTVTASNRLGS 9113

Query: 1135 VEIECKLEV 1143
            V     +EV
Sbjct: 9114 VFRNVHVEV 9122



 Score = 92.0 bits (227), Expect = 3e-18
 Identities = 98/417 (23%), Positives = 169/417 (40%), Gaps = 47/417 (11%)

Query: 745   PPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTI 804
             PP  + +D V+  ++T+ W PP++ G   +  Y++E     +  W + ++  + +T   I
Sbjct: 19118 PPGPIRIDEVSCDSITISWNPPEYDGGCQISNYIVEKKETTSTTWHIVSQ-AVARTSIKI 19176

Query: 805   TGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPP----KIRIPRHLKQTYIRR- 859
               L T ++   RV A N  G S     S  ++ +    PP      ++    K T +   
Sbjct: 19177 VRLTTGSEYQFRVCAENRYGKSSYSE-SSAVVAEYPFSPPGPPGTPKVVHATKSTMLVTW 19235

Query: 860   ---VGEAVNLVIPF--QGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSG 914
                V +  + VI +  + K R  + W K       N+I I     DT + +   +     
Sbjct: 19236 QVPVNDGGSRVIGYHLEYKERSSILWSK------ANKILI----ADTQMKVSGLDEGLMY 19285

Query: 915   KYDLQVKVDKFVETASIDIQII------DRPGPPQIVKIEDVWGENVALTWTPPKDDGNA 968
             +Y +  +    +   S   + +      D PG P++  I     ++V+L W+ P  DG A
Sbjct: 19286 EYRVYAENIAGIGKCSKSCEPVPARDPCDPPGQPEVTNITR---KSVSLKWSKPHYDGGA 19342

Query: 969   AITGYTIQKADKKSMEWFTV-IEHYHRTSATITELVIGNEYYFRVFSENMC-GLSEDATM 1026
              ITGY +++ +     W      +   T   +TEL     Y FRVF+ N    +SE +  
Sbjct: 19343 KITGYIVERRELPDGRWLKCNYTNIQETYFEVTELTEDQRYEFRVFARNAADSVSEPSES 19402

Query: 1027  TKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKIT 1086
             T    +I +D  +    V  D  F +  +           AG    +N  + G P P I+
Sbjct: 19403 T--GPIIVKDD-VEPPRVMMDVKFRDVIVVK---------AGEVLKINADIAGRPLPVIS 19450

Query: 1087  WMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGT--VEIECKL 1141
             W K+ + I +  R  + S      L ++     D G Y     N  GT  V + CK+
Sbjct: 19451 WAKDGIEIEERARTEIISTDNHTLLTVKDCIRRDTGQYVLTLKNVAGTRSVAVNCKV 19507



 Score = 92.0 bits (227), Expect = 3e-18
 Identities = 69/216 (31%), Positives = 100/216 (46%), Gaps = 18/216 (8%)

Query: 937   DRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTV-IEHYHRT 995
             ++PG P    I  V  ++  + W PP  DG A I  Y ++K +KK  +W +V  E    T
Sbjct: 24451 EKPGAPGKPTITAVTKDSCVVAWKPPASDGGAKIRNYYLEKREKKQNKWISVTTEEIRET 24510

Query: 996   SATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFS-EAP 1054
               ++  L+ G EY FRV  EN+ G SE + +++              P+    D   +AP
Sbjct: 24511 VFSVKNLIEGLEYEFRVKCENLGGESEWSEISE--------------PITPKSDVPIQAP 24556

Query: 1055  MFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMK-NKVAIVDDPRYRMFS-NQGVCTLE 1112
              F + L N       NATL C V G+PKP + W +  K  I D  +YR+     G   L 
Sbjct: 24557 HFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQLI 24616

Query: 1113  IRKPSPYDGGTYCCKAVNDLGTVEIECKLEVKVIAQ 1148
             I   +  D   Y  +A N  G+V     LEV+V A+
Sbjct: 24617 IASVTDDDATVYQVRATNQGGSVSGTASLEVEVPAK 24652



 Score = 90.9 bits (224), Expect = 6e-18
 Identities = 99/442 (22%), Positives = 167/442 (37%), Gaps = 60/442 (13%)

Query: 722   VNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEY 781
             +  + +  P  P  PF             +  +     ++ W  P   G + +  Y++E 
Sbjct: 12612 IKVVVMDAPGPPQPPF------------DISDIDADACSLSWHIPLEDGGSNITNYIVEK 12659

Query: 782   CFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEI- 840
             C     DW+ A    + KT   +  L    +   RV+A N  G SEP   + P +V +  
Sbjct: 12660 CDVSRGDWVTALAS-VTKTSCRVGKLIPGQEYIFRVRAENRFGISEP--LTSPKMVAQFP 12716

Query: 841   ----IEPPKIRIPRHLKQ----TYIRRVGEAVNLVIPF--QGKPRPELTWKKDGAEIDKN 890
                  EP   R+ +  K      + R   +  + +I +  + K R  L W K       N
Sbjct: 12717 FGVPSEPKNARVTKVNKDCIFVAWDRPDSDGGSPIIGYLIERKERNSLLWVK------AN 12770

Query: 891   QINIRNSETDTIIFIRKAERS------HSGKYDLQVKVDKFVETASIDIQIIDRPGPPQI 944
                +R++E      +   E S      +        K  ++V TA + +   D PG P++
Sbjct: 12771 DTLVRSTEYPCAGLVEGLEYSFRIYALNKAGSSPPSKPTEYV-TARMPV---DPPGKPEV 12826

Query: 945   VKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWF---TVIEHYHRTSATITE 1001
             +   DV    V+L W  PK DG + I GY ++       +W    T      +   T T 
Sbjct: 12827 I---DVTKSTVSLIWARPKHDGGSKIIGYFVEACKLPGDKWVRCNTAPHQIPQEEYTATG 12883

Query: 1002  LVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLV 1061
             L    +Y FR  +     +S  +  +    ++A +      P   D   +   + T    
Sbjct: 12884 LEEKAQYQFRAIARTAVNISPPSEPSDPVTILAENV-----PPRIDLSVAMKSLLTVK-- 12936

Query: 1062  NTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDG 1121
                  AG N  L+ +V G P P ++W K+   +      +M   + +CTLE+   +  D 
Sbjct: 12937 -----AGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDS 12991

Query: 1122  GTYCCKAVNDLGTVEIECKLEV 1143
             G Y   A N  G+     KL+V
Sbjct: 12992 GDYTITAENSSGSKSATIKLKV 13013



 Score = 89.4 bits (220), Expect = 2e-17
 Identities = 117/543 (21%), Positives = 204/543 (37%), Gaps = 60/543 (11%)

Query: 628   NEAGEAHASIKVKVVDFPDP-----PVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIE 682
             N AG   AS+        DP     P  P VT+       + W PP  DGGS + GY +E
Sbjct: 10027 NAAGVGPASLPSDPATARDPIAPPGPPFPKVTDWTKSSADLEWSPPLKDGGSKVTGYIVE 10086

Query: 683   RKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAV 742
              K++    W +      + T      + EG  Y+   F V A+ I+    P    V   +
Sbjct: 10087 YKEEGKEEWEKGKDKEVRGTKLVVTGLKEGAFYK---FRVRAVNIAGIGEPGE--VTDVI 10141

Query: 743   TSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKF 802
                  L++ D   D +V  R R   H G        +      T  W +  + L  +   
Sbjct: 10142 EMKDRLVSPDLQLDASV--RDRIVVHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEATI 10199

Query: 803   TITGLPTDAKI---------FVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIP---- 849
               T + +   I            + A N AG  +     + I+V  +  P  +  P    
Sbjct: 10200 ETTAISSSMVIKNCQRSHQGVYSLLAKNEAGERK-----KTIIVDVLDVPGPVGTPFLAH 10254

Query: 850   ----RHLKQTYIRRVGEAVNLVIPF--QGKPRPELTWKKDGAEIDKNQINIRNSETDTII 903
                    K T+     +  + +  +  + +      W      + +    ++        
Sbjct: 10255 NLTNESCKLTWFSPEDDGGSPITNYVIEKRESDRRAWTPVTYTVTRQNATVQGLIQGKAY 10314

Query: 904   FIRKAERSHSGKYDLQVKVDKFVETASIDI--QIIDRPGPPQIVKIEDVWGENVALTWTP 961
             F R A  +  G       +  FVET+   +  + I  P  P+ +++++V    V LTW P
Sbjct: 10315 FFRIAAENSIG-------MGPFVETSEALVIREPITVPERPEDLEVKEVTKNTVTLTWNP 10367

Query: 962   PKDDGNAAITGYTIQKADKKSMEWFTVI-EHYHRTSATITELVIGNEYYFRVFSENMCGL 1020
             PK DG + I  Y ++     + ++  V  ++      T+  L  G+ Y +RV + N+ G 
Sbjct: 10368 PKYDGGSEIINYVLESRLIGTEKFHKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQ 10427

Query: 1021  SEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGN 1080
              + +  TK    I    ++    ++ DF        T  +   +A+ G  +       G 
Sbjct: 10428 GKPSFCTKP---ITCKDELAPPTLHLDF----RDKLTIRVGEAFALTGRYS-------GK 10473

Query: 1081  PKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECK 1140
             PKPK++W K++  +++D R  + +      LE  K    D G YC    N  G+ +  C+
Sbjct: 10474 PKPKVSWFKDEADVLEDDRTHIKTTPATLALEKIKAKRSDSGKYCVVVENSTGSRKGFCQ 10533

Query: 1141  LEV 1143
             + V
Sbjct: 10534 VNV 10536



 Score = 87.0 bits (214), Expect = 9e-17
 Identities = 96/437 (21%), Positives = 162/437 (37%), Gaps = 75/437 (17%)

Query: 625   NLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERK 684
             N+  ++  +  S  +  +D  DPP  P    +      + W  P Y GG  I  Y +E++
Sbjct: 14965 NMAGKSKPSKPSEPMLALDPIDPPGKPVPLNITRHTVTLKWAKPEYTGGFKITSYIVEKR 15024

Query: 685   KKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIG-ISKPSMPSRPFVPLAVT 743
                + RW++ NF    E  F    + E  AYE R+ A NA G IS PS PS         
Sbjct: 15025 DLPNGRWLKANFSNILENEFTVSGLTEDAAYEFRVIAKNAAGAISPPSEPSDAITCRDDV 15084

Query: 744   SPPTLLTVDSVTDTTV-------------------TMRWRP--PDHIGAAGLDGYVLEYC 782
               P +       DT +                   TM W     +  G A L+  + ++ 
Sbjct: 15085 EAPKIKVDVKFKDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFS 15144

Query: 783   FEGTEDWIVANKDLI--DKTKFTITGLPTD--AKIFVRVKAVNAAGASEPKYYSQPILVK 838
                     + NKD    D   +T+T       AK    VK ++  G  E      P+ V 
Sbjct: 15145 TN------LVNKDSTRRDSGAYTLTATNPGGFAKHIFNVKVLDRPGPPE-----GPLAVT 15193

Query: 839   EIIE--------PPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKN 890
             E+          PP            +   G  ++  I  Q +    L W    +E+   
Sbjct: 15194 EVTSEKCVLSWFPP------------LDDGGAKIDHYI-VQKRETSRLAWTNVASEVQVT 15240

Query: 891   QINI-RNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIED 949
             ++ + +  + +  IF   A   +     L+           + +     P PP+  ++  
Sbjct: 15241 KLKVTKLLKGNEYIFRVMAVNKYGVGEPLE-------SEPVLAVNPYGPPDPPKNPEVTT 15293

Query: 950   VWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWF-----TVIEHYHRTSATITELVI 1004
             +  +++ + W  P  DG + I  Y +++ DK    W      T+ +  ++ S     L  
Sbjct: 15294 ITKDSMVVCWGHPDSDGGSEIINYIVERRDKAGQRWIKCNKKTLTDLRYKVSG----LTE 15349

Query: 1005  GNEYYFRVFSENMCGLS 1021
             G+EY FR+ +EN  G+S
Sbjct: 15350 GHEYEFRIMAENAAGIS 15366



 Score = 86.3 bits (212), Expect = 2e-16
 Identities = 94/359 (26%), Positives = 158/359 (44%), Gaps = 23/359 (6%)

Query: 310  WYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVT---AGDEKCST-ELFVREP 365
            W K+G  IR S K+ F   G  R L I + Q++D  EY         EK ST +L V E 
Sbjct: 4779 WMKDGSNIRESPKHRFIADGKDRKLHIIDVQLSDAGEYTCVLRLGNKEKTSTAKLVVEEL 4838

Query: 366  PIMVTKQL-EDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHI 424
            P+   K L E+ T   G+ + L CE+++ + +V W K+G+ ++  P  R    V G    
Sbjct: 4839 PVRFVKTLEEEVTVVKGQPLYLSCELNK-ERDVVWRKDGKIVVEKP-GRIVPGVIGLMRA 4896

Query: 425  LIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKIL-----TPLTDQTVNLGKEICLKC 479
            L I  A   DA  Y+V T    ++ + S  +K ++++      P+ DQ V         C
Sbjct: 4897 LTINDADDTDAGTYTV-TVENANNLECSSCVKVVEVIRDWLVKPIRDQHVKPKGTAIFAC 4955

Query: 480  EISENIPG-KWTK--NGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVT 536
            +I+++ P  KW K  + +P + +D+ +++  G    L I NA+ ED  +Y  A +     
Sbjct: 4956 DIAKDTPNIKWFKGYDEIPAEPNDKTEILRDGNHLYLKIKNAMPEDIAEY--AVEIEGKR 5013

Query: 537  LPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSG 596
             PAK+ + +    +L  ++    VT+        +  IS    P     +G+  ++  S 
Sbjct: 5014 YPAKLTLGEREVELLKPIE---DVTIYEKESASFDAEISEADIPGQWKLKGE--LLRPSP 5068

Query: 597  RIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTE 655
                ++      L +   + D +G       N    A  ++K   +DF  P    TV E
Sbjct: 5069 TCEIKAEGGKRFLTLHKVKLDQAGEVLYQALNAITTAILTVKEIELDFAVPLKDVTVPE 5127



 Score = 86.3 bits (212), Expect = 2e-16
 Identities = 104/434 (23%), Positives = 164/434 (37%), Gaps = 44/434 (10%)

Query: 722   VNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEY 781
             ++ I + KP  P  P            +  D V+   V + W PP + G   +  Y++E 
Sbjct: 18025 LSVIVLEKPGPPVGP------------VRFDEVSADFVVISWEPPAYTGGCQISNYIVEK 18072

Query: 782   CFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILV---- 837
                 T  W + +   + +T   IT L T  +   R+ A N  G S P   S+ ++V    
Sbjct: 18073 RDTTTTTWHMVSAT-VARTTIKITKLKTGTEYQFRIFAENRYGKSAP-LDSKAVIVQYPF 18130

Query: 838   KEIIEPPKIRIPRHLKQTYIRRVGEAVN------LVIPFQGKPRPELTWKKDGAEIDKNQ 891
             KE   P    +    K   + +  E VN      +    + K +  + W K    ++K  
Sbjct: 18131 KEPGPPGTPFVTSISKDQMLVQWHEPVNDGGTKIIGYHLEQKEKNSILWVK----LNKTP 18186

Query: 892   INIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVW 951
             I     +T  +    + E   S +  + +     V    +     D PG P+ + I    
Sbjct: 18187 IQDTKFKTTGLDEGLEYEFKVSAENIVGIGKPSKVSECFVARDPCDPPGRPEAIVITR-- 18244

Query: 952   GENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTV-IEHYHRTSATITELVIGNEYYF 1010
               NV L W  P  DG + ITGY ++K D     W      +   T  T++ LV    Y F
Sbjct: 18245 -NNVTLKWKKPAYDGGSKITGYIVEKKDLPDGRWMKASFTNVLETEFTVSGLVEDQRYEF 18303

Query: 1011  RVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYN 1070
             RV + N  G   + +     A+ ARD     N   +       P +   +V     AG  
Sbjct: 18304 RVIARNAAGNFSEPS-DSSGAITARDEIDAPNASLD-------PKYKDVIV---VHAGET 18352

Query: 1071  ATLNCSVRGNPKPKITWMKNKVAIVDD-PRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAV 1129
               L   +RG P P + W K+   + +   R  + S     TL ++     DGG Y  K  
Sbjct: 18353 FVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQYILKLS 18412

Query: 1130  NDLGTVEIECKLEV 1143
             N  GT  I   ++V
Sbjct: 18413 NVGGTKSIPITVKV 18426



 Score = 86.3 bits (212), Expect = 2e-16
 Identities = 78/292 (26%), Positives = 125/292 (42%), Gaps = 60/292 (20%)

Query: 290   DKGGRVRFV--VELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEY 347
             ++GG V++V  +E  D   +V WY   +++  S KY   ++    IL++ +    DD  Y
Sbjct: 25208 EEGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTY 25267

Query: 348   YVTA----GDEKCSTELFVR---------------------------EPPIMVTKQLEDT 376
                     G++    ELFV+                           E P   T  L + 
Sbjct: 25268 RCKVVNDYGEDSSYAELFVKGVREVYDYYCRRTMKKIKRRTDTMRLLERPPEFTLPLYNK 25327

Query: 377   TAYCGERVELECEVS-EDDANVKWFKNGEEIIPGPK-SRYRIRVEGKKHILIIEGATKAD 434
             TAY GE V     ++   + +V W+K+G++I PG    +Y    +   + L I   T  D
Sbjct: 25328 TAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDD 25387

Query: 435   AAEYSVMTTG--GQSS--AKLSVDLKPLKILTPLTDQTV-------------NLGKEICL 477
              AEY+V+     G+ S  AKL+V L P     P TD T+               G+ +C 
Sbjct: 25388 DAEYTVVARNKYGEDSCKAKLTVTLHP-----PPTDSTLRPMFKRLLANAECQEGQSVCF 25442

Query: 478   KCEISENIPG--KWTKNGLPVQESDRLKVVHKG-RIHKLVIANALTEDEGDY 526
             +  +S   P   KW K+G P+     ++++H+G   + L I + L ED G Y
Sbjct: 25443 EIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYY 25494



 Score = 85.9 bits (211), Expect = 2e-16
 Identities = 102/444 (22%), Positives = 169/444 (38%), Gaps = 63/444 (14%)

Query: 721   AVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLE 780
             ++  + + KP  P  P            +  D V+  ++T+ W PP + G   +  Y+++
Sbjct: 16942 SIEIVTLDKPDPPKGP------------VKFDDVSAESITLSWNPPLYTGGCQITNYIVQ 16989

Query: 781   YCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEI 840
                  T  W V +   + +T   +T L T  +   R+ A N  G S     S PI+ +  
Sbjct: 16990 KRDTTTTVWDVVSAT-VARTTLKVTKLKTGTEYQFRIFAENRYGQSFA-LESDPIVAQYP 17047

Query: 841   IE---PPKIRIPRHL-KQTYIRRVGEAVN------LVIPFQGKPRPELTWKKDGAEIDKN 890
              +   PP       + K + + +  E VN      +    + K R  + W K    ++K 
Sbjct: 17048 YKEPGPPGTPFATAISKDSMVIQWHEPVNNGGSPVIGYHLERKERNSILWTK----VNKT 17103

Query: 891   QINIRNSETDTIIFIRKAERSHSG-KYDLQVKVDKFVETAS--------IDIQIIDRPGP 941
              I+      DT     KA+    G +Y+ +V  +  V            +     D PG 
Sbjct: 17104 IIH------DTQF---KAQNLEEGIEYEFRVYAENIVGVGKASKNSECYVARDPCDPPGT 17154

Query: 942   PQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTV-IEHYHRTSATIT 1000
             P+ + ++      + L WT P  DG + ITGY ++K D     W      +   T  T++
Sbjct: 17155 PEPIMVKR---NEITLQWTKPVYDGGSMITGYIVEKRDLPDGRWMKASFTNVIETQFTVS 17211

Query: 1001  ELVIGNEYYFRVFSENMCG-LSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQP 1059
              L     Y FRV ++N  G +S+ +  T         G I      E    S  P F   
Sbjct: 17212 GLTEDQRYEFRVIAKNAAGAISKPSDST---------GPITAKDEVELPRISMDPKFRDT 17262

Query: 1060  LVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPY 1119
             +V     AG    L   V G P P I W++    I +  R  + +      L ++     
Sbjct: 17263 IVVN---AGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRI 17319

Query: 1120  DGGTYCCKAVNDLGTVEIECKLEV 1143
             DGG Y  +A N  G+      ++V
Sbjct: 17320 DGGQYILRASNVAGSKSFPVNVKV 17343



 Score = 84.3 bits (207), Expect = 6e-16
 Identities = 105/451 (23%), Positives = 168/451 (37%), Gaps = 79/451 (17%)

Query: 722   VNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEY 781
             +  I + KP  P+ P            + +D +  T++T+ W PP+  G A L GYV+E 
Sbjct: 23452 IKVIILDKPGPPTGP------------IKIDEIDATSITISWEPPELDGGAPLSGYVVEQ 23499

Query: 782   CFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEII 841
                    W+  ++  + ++ F  T L    +   RV A N  G           L  E+I
Sbjct: 23500 RDAHRPGWLPVSES-VTRSTFKFTRLTEGNEYVFRVAATNRFGIGS-------YLQSEVI 23551

Query: 842   E-PPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTW---KKDGAE------IDKNQ 891
             E    IRIP           G    L I    +    LTW   + DG        +++ +
Sbjct: 23552 ECRSSIRIP-----------GPPETLQIFDVSRDGMTLTWYPPEDDGGSQVTGYIVERKE 23600

Query: 892   INIR-----NSETDTIIFIRKAERSHSGKYDLQVKVDKFVETAS--------IDIQIIDR 938
             +        N    T+   R    +   +Y+ +V       +          + +  I  
Sbjct: 23601 VRADRWVRVNKVPVTMTRYRSTGLTEGLEYEHRVTAINARGSGKPSRPSKPIVAMDPIAP 23660

Query: 939   PGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWF------TVIEHY 992
             PG PQ  ++ D    +V+L W+ P+D+G + +TGY I+       EW       T I  Y
Sbjct: 23661 PGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTKCNTTPTKIREY 23720

Query: 993   HRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSE 1052
                  T+T L  G EY FRV + N  G  E A        +    K+ +   Y D++  E
Sbjct: 23721 -----TLTHLPQGAEYRFRVLACNAGGPGEPAE-------VPGTVKVTEMLEYPDYELDE 23768

Query: 1053  APMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLE 1112
                  +     +   G    L   ++G P P   W K    I    R  + +++    L 
Sbjct: 23769 -----RYQEGIFVRQGGVIRLTIPIKGKPFPICKWTKEGQDI--SKRAMIATSETHTELV 23821

Query: 1113  IRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1143
             I++    D GTY     N  G   +  K+ V
Sbjct: 23822 IKEADRGDSGTYDLVLENKCGKKAVYIKVRV 23852



 Score = 84.0 bits (206), Expect = 8e-16
 Identities = 93/410 (22%), Positives = 160/410 (39%), Gaps = 66/410 (16%)

Query: 288  QVDKGGRVRFVVELADPKLEVKWYKNGQEI----RPSTKYIFEHKGCQRILFINNCQMTD 343
            QV +  R     E+ +  ++  WYK+G EI    +   KY+ E +     +FI+  + +D
Sbjct: 3111 QVIEKQRAVVEFEVNEDDVDAHWYKDGIEINFQVQERHKYVVERR--IHRMFISETRQSD 3168

Query: 344  DSEYYVTAGDEKCSTELFVREP-PIMVTKQLEDTTAYCGERVELECEVS-EDDANVKWFK 401
              EY   AG  + S  L+V  P P  V ++L+  T   G+       +S      + W+K
Sbjct: 3169 AGEYTFVAGRNRSSVTLYVNAPEPPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYK 3228

Query: 402  NGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAA--------EYSVMTTGGQSSAKL-- 451
              + +  G K ++    +G+++ L++  A   DAA        +Y V TT    S ++  
Sbjct: 3229 EEQLLSTGFKCKF--LHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPE 3286

Query: 452  ------SVDLKPLKILTPLTDQTVNLGKEICLKCEIS-ENIPGKWTKNGLPVQESDRLKV 504
                   + + P  I+TPL D   + G+    +C +S  ++   W      ++ S   ++
Sbjct: 3287 VVSPDQEMPVYPPAIITPLQDTVTSEGQPARFQCRVSGTDLKVSWYSKDKKIKPSRFFRM 3346

Query: 505  VHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKIILDGLD--ADNT--- 559
                  ++L IA A  EDEG Y F      V   A   V     + L+G     +NT   
Sbjct: 3347 TQFEDTYQLEIAEAYPEDEGTYTF------VASNAVGQVSSTANLSLEGFSKFEENTSNS 3400

Query: 560  ---------------------------VTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIM 592
                                       + V  G  +R    +SG P P+  W    + I+
Sbjct: 3401 QWHVSLSVSFKKEPLGQKPSFIQPLSSLRVHNGETVRFHARVSGIPKPEIQWFHNQQLIL 3460

Query: 593  EGSGRI-RTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKV 641
                 +   E     + ++I  A  + +G Y     N AGEA  +  + V
Sbjct: 3461 PTKDVVFHFEESTGMALMLIVDAYSEHAGQYSCKAANSAGEATCAATLTV 3510



 Score = 82.8 bits (203), Expect = 2e-15
 Identities = 59/194 (30%), Positives = 92/194 (47%), Gaps = 21/194 (10%)

Query: 572  IPISGEPPPKAMWSRGDKAIMEGSGRIRTE-------SYPDSSTLVIDIAERDDSGVYHI 624
            + +  EPP         + ++E   R+ T        + PD +  V D+ E  +   + +
Sbjct: 7828 VDLKWEPPKNDGGRPIQRYVIEKKERLGTRWVKAGKTAGPDCNFRVTDVIEGTEVQ-FQV 7886

Query: 625  NLKNEAGEAHASIKVKVVDFPDPPVAPT------VTEVGDDWCIMNWEPPAYDGGSPILG 678
              +NEAG  H S   +++   DP   P+      VT+ G     + W+PP  +GGSPI+G
Sbjct: 7887 RAENEAGVGHPSEPTEILSIEDPTSPPSPPLDLHVTDAGRKHIAIAWKPPEKNGGSPIIG 7946

Query: 679  YFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVA----YEVRIFAVNAIGISKPSMPS 734
            Y +E     + +WMR+N    K+  F   K+ EGV     Y +R+ AVNAIG+S+PS  S
Sbjct: 7947 YHVEMCPVGTEKWMRVNSRPIKDLKF---KVEEGVVPDKEYVLRVRAVNAIGVSEPSEIS 8003

Query: 735  RPFVPLAVTSPPTL 748
               V       PT+
Sbjct: 8004 ENVVAKDPDCKPTI 8017



 Score = 75.5 bits (184), Expect = 3e-13
 Identities = 105/447 (23%), Positives = 173/447 (38%), Gaps = 58/447 (12%)

Query: 721   AVNAIGISKPSMPSR-PFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVL 779
             A NA G +K  +  +    P  V  P   +   ++T   +T+ W  P + G A +  Y++
Sbjct: 21661 AKNASGSAKAEIKVKVQDTPGKVVGP---IRFTNITGEKMTLWWDAPLNDGCAPITHYII 21717

Query: 780   EYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVK- 838
             E        W +  +D  +   +T   L    +   RV AVN  G   P   S P++ + 
Sbjct: 21718 EKRETSRLAWALI-EDKCEAQSYTAIKLINGNEYQFRVSAVNKFGVGRP-LDSDPVVAQI 21775

Query: 839   --EIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRN 896
                + + P I  P ++        G ++ L        RPE      G+EI +  +  R 
Sbjct: 21776 QYTVPDAPGIPEPSNI-------TGNSITLTWA-----RPE---SDGGSEIQQYILERRE 21820

Query: 897   SE-TDTIIFIRKAERSHS----------GKYDLQVKVDKF--VETASIDIQII------D 937
              + T  +  I K   S +           +Y+  V  +    V  AS   ++I      +
Sbjct: 21821 KKSTRWVKVISKRPISETRFKVTGLTEGNEYEFHVMAENAAGVGPASGISRLIKCREPVN 21880

Query: 938   RPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTV-IEHYHRTS 996
              PGPP +VK+ D     V+L W+ P  DG   I GY I+       +W  V  E   +T 
Sbjct: 21881 PPGPPTVVKVTDTSKTTVSLEWSKPVFDGGMEIIGYIIEMCKADLGDWHKVNAEACVKTR 21940

Query: 997   ATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMF 1056
              T+T+L  G EY FRV + N  G  +   +T     I    ++    +  D +F +  + 
Sbjct: 21941 YTVTDLQAGEEYKFRVSAINGAGKGDSCEVT---GTIKAVDRLTAPELDIDANFKQTHVV 21997

Query: 1057  TQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKP 1116
                       AG +  L  + +G P P   W K    +    R  + +     TL +   
Sbjct: 21998 R---------AGASIRLFIAYQGRPTPTAVWSKPDSNL--SLRADIHTTDSFSTLTVENC 22046

Query: 1117  SPYDGGTYCCKAVNDLGTVEIECKLEV 1143
             +  D G Y     N+ G+  I   ++V
Sbjct: 22047 NRNDAGKYTLTVENNSGSKSITFTVKV 22073



 Score = 73.9 bits (180), Expect = 8e-13
 Identities = 64/235 (27%), Positives = 91/235 (38%), Gaps = 46/235 (19%)

Query: 939  PGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRT-SA 997
            P PP  V++ +   E + +TW PP  DG + I GY I+K  K    W    EH     + 
Sbjct: 8208 PDPPVDVEVHNPTAEAMTITWKPPLYDGGSKIMGYIIEKIAKGEERWKRCNEHLVPILTY 8267

Query: 998  TITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFT 1057
            T   L  G EY FRV +EN  G+SE +  T  +  +            +  D  +  + T
Sbjct: 8268 TAKGLEEGKEYQFRVRAENAAGISEPSRATPPTKAV------------DPIDAPKVILRT 8315

Query: 1058 QPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDD-------PRYRM-------- 1102
               V      G    L+ S+ G+P P ITW+K++  IV +       P  R         
Sbjct: 8316 SLEVKR----GDEIALDASISGSPYPTITWIKDENVIVPEEIKKRAAPLVRRRKGEVQEE 8371

Query: 1103 --------------FSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1143
                           S +G   L +R     D G Y  K  ND G  +  C + V
Sbjct: 8372 EPFVLPLTQRLSIDNSKKGESQLRVRDSLRPDHGLYMIKVENDHGIAKAPCTVSV 8426



 Score = 73.9 bits (180), Expect = 8e-13
 Identities = 59/203 (29%), Positives = 83/203 (40%), Gaps = 14/203 (6%)

Query: 933   IQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHY 992
             ++  + P PP  + I D+    V+L W  PK DG + ITGY I+   K S +W T I   
Sbjct: 14587 VKASEAPSPPDSLNIMDITKSTVSLAWPKPKHDGGSKITGYVIEAQRKGSDQW-THITTV 14645

Query: 993   HRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSE 1052
                   +  L  G EY F+V + N  G S      +ES  +     + +  +  + D   
Sbjct: 14646 KGLECVVRNLTEGEEYTFQVMAVNSAGRSAP----RESRPVI----VKEQTMLPELDLRG 14697

Query: 1053  APMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLE 1112
                  Q LV   A AG N  +   V G PKP +TW K    +    R    +      L 
Sbjct: 14698 ---IYQKLV--IAKAGDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILN 14752

Query: 1113  IRKPSPYDGGTYCCKAVNDLGTV 1135
             I +    D G Y   A N +G V
Sbjct: 14753 INECVRSDSGPYPLTARNIVGEV 14775



 Score = 73.2 bits (178), Expect = 1e-12
 Identities = 52/197 (26%), Positives = 86/197 (43%), Gaps = 13/197 (6%)

Query: 937   DRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTS 996
             ++P PP+ + + D    +  L W  P  DG + ITGY ++   K S  W     H  + +
Sbjct: 22172 EQPAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSDFWVEA-GHTKQLT 22230

Query: 997   ATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMF 1056
              T+  LV   EY FRV ++N  G SE       S+VI ++ +I           ++    
Sbjct: 22231 FTVERLVEKTEYEFRVKAKNDAGYSEPREAF--SSVIIKEPQIEPT--------ADLTGI 22280

Query: 1057  TQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKP 1116
             T  L+   A  G   T++  + G P PK+TW   ++ + +  R  + + +   TL ++  
Sbjct: 22281 TNQLITCKA--GSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVSITTTKDRTTLTVKDS 22338

Query: 1117  SPYDGGTYCCKAVNDLG 1133
                D G Y     N  G
Sbjct: 22339 MRGDSGRYFLTLENTAG 22355



 Score = 68.9 bits (167), Expect = 3e-11
 Identities = 135/688 (19%), Positives = 232/688 (33%), Gaps = 145/688 (21%)

Query: 2     PEPTKKEENEVPAP----APPPEEPSKEKEAGTTPAKDEEEVSPPSALPPGLGSRALERK 57
             PEP  K    V +P    +P P  P       T P   E+    P + PP +        
Sbjct: 26297 PEPRVKSPEAVKSPKRVKSPEPSHPKAVSPTETKPTPTEKVQHLPVSAPPKITQ------ 26350

Query: 58    DSDWTLVETPPGEEQAKQNANSQLSILFIEKPQGGTVKVGEDITFIAKVKAEDLLRKPTI 117
                                        F++       +  ++I  +  V    +LR   +
Sbjct: 26351 ---------------------------FLK------AEASKEIAKLTCVVESSVLRAKEV 26377

Query: 118   KWFKGKWMDLASKAGKHLQLKETFERH-SRVYTFEMQIIKAKDNFAGNYRCEVTYKDKFD 176
              W+K          GK L+    F+ H S   T+E++I    ++  G Y CE+       
Sbjct: 26378 TWYKD---------GKKLKENGHFQFHYSADGTYELKINNLTESDQGEYVCEI------- 26421

Query: 177   SCSFDLEVHESTGTTPNIDIRSAFKRSGEGQEDAGELDFSG---------LLKRREVKQQ 227
                                       SGEG      L F G         + K  E K+ 
Sbjct: 26422 --------------------------SGEGGTSKTNLQFMGQAFKSIHEKVSKISETKKS 26455

Query: 228   EEEPQVDVWELLKNAKPSEYEKIAFQYGITDLRGMLKRLKRMRREEKKSAAFAKILDPAY 287
             +++       + +  +P   E I+                       K      + D   
Sbjct: 26456 DQKTTEST--VTRKTEPKAPEPIS----------------------SKPVIVTGLQDTTV 26491

Query: 288   QVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEY 347
               D   +   V    +P+    W K+G+ I    KY          L I+    +D   Y
Sbjct: 26492 SSDSVAKFA-VKATGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLY 26550

Query: 348   YVT----AGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNG 403
               T    AG    S +L ++   I  T+  + +T    E    +  V +++ + K  ++ 
Sbjct: 26551 TCTVKNSAGSVSSSCKLTIKA--IKDTEAQKVSTQKTSEITPQKKAVVQEEISQKALRSE 26608

Query: 404   EEIIPGPKSRYRIRVEGKKHILIIEGATKADAA---EYSVMTTGGQSSAKLSVDLKP-LK 459
             E  +   KS+ ++ ++ +   ++I    K  AA   E S++      +++ S +++   +
Sbjct: 26609 EIKMSEAKSQEKLALKEEASKVLISEEVKKSAATSLEKSIVHEEITKTSQASEEVRTHAE 26668

Query: 460   ILTPLTDQTVNLGKEICLKCEISENIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANAL 519
             I    T  ++N G+ + LK  I+     KW  NG+ +  S+  +    G    L I  A 
Sbjct: 26669 IKAFSTQMSINEGQRLVLKANIAGATDVKWVLNGVELTNSEEYRYGVSGSDQTLTIKQAS 26728

Query: 520   TEDEGDYV--------FAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLE 571
               DEG                Y++TL  ++   D P  I        +  +  G  +   
Sbjct: 26729 HRDEGILTCISKTKEGIVKCQYDLTLSKELS--DAPAFI----SQPRSQNINEGQNVLFT 26782

Query: 572   IPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAG 631
               ISGEP P+  W + +  I   S  +      +  +L I  A   DSG Y I  KN  G
Sbjct: 26783 CEISGEPSPEIEWFKNNLPI-SISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRG 26841

Query: 632   EAHASIKVKVVDFPDPPVAPTVTEVGDD 659
             +  A+  + V+   + P    V     D
Sbjct: 26842 QCSATASLMVLPLVEEPSREVVLRTSGD 26869



 Score = 66.2 bits (160), Expect = 2e-10
 Identities = 94/408 (23%), Positives = 146/408 (35%), Gaps = 40/408 (9%)

Query: 742   VTSPPT-LLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKT 800
             +  PPT  +  D V+   VT  W PP++ G   +  YV+E     +  W+     +I +T
Sbjct: 14786 IPGPPTGPIKFDEVSSDFVTFSWDPPENDGGVPISNYVVEMRQTDSTTWVELATTVI-RT 14844

Query: 801   KFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQ-TYIRR 859
              +  T L T  +   RVKA N  G   P   S  I+      P K+  P    Q T + +
Sbjct: 14845 TYKATRLTTGLEYQFRVKAQNRYGVG-PGITSACIVANY---PFKVPGPPGTPQVTAVTK 14900

Query: 860   VGEAVNLVIPF------------QGKPRPELTWKKDGAEIDKNQINIRNSETDTIIF-IR 906
                 ++   P             + K R  + W+     +    I   +  TD I +  R
Sbjct: 14901 DSMTISWHEPLSDGGSPILGYHVERKERNGILWQTVSKALVPGNIFKSSGLTDGIAYEFR 14960

Query: 907   KAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDG 966
                 + +GK     K  K  E   + +  ID PG P  + I       V L W  P+  G
Sbjct: 14961 VIAENMAGKS----KPSKPSEPM-LALDPIDPPGKPVPLNITR---HTVTLKWAKPEYTG 15012

Query: 967   NAAITGYTIQKADKKSMEWFTV-IEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDAT 1025
                IT Y ++K D  +  W      +      T++ L     Y FRV ++N  G     +
Sbjct: 15013 GFKITSYIVEKRDLPNGRWLKANFSNILENEFTVSGLTEDAAYEFRVIAKNAAGAISPPS 15072

Query: 1026  MTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKI 1085
                ++     D +  K  V  D  F +  +           AG    L   V G P P +
Sbjct: 15073 EPSDAITCRDDVEAPKIKV--DVKFKDTVILK---------AGEAFRLEADVSGRPPPTM 15121

Query: 1086  TWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLG 1133
              W K+   +    +  +        L  +  +  D G Y   A N  G
Sbjct: 15122 EWSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDSGAYTLTATNPGG 15169



 Score = 64.7 bits (156), Expect = 5e-10
 Identities = 75/303 (24%), Positives = 129/303 (42%), Gaps = 19/303 (6%)

Query: 366  PIMVTKQLEDT----TAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGK 421
            P+   K+++D     + + G     EC VS   A   W K+G  I   PK  +R   +GK
Sbjct: 4742 PLKFVKEIKDIILTESEFVGSSAIFECLVSPSTAITTWMKDGSNIRESPK--HRFIADGK 4799

Query: 422  KHILIIEGATKADAAEYSVMTTGGQ----SSAKLSVDLKPLKILTPLTDQ-TVNLGKEIC 476
               L I     +DA EY+ +   G     S+AKL V+  P++ +  L ++ TV  G+ + 
Sbjct: 4800 DRKLHIIDVQLSDAGEYTCVLRLGNKEKTSTAKLVVEELPVRFVKTLEEEVTVVKGQPLY 4859

Query: 477  LKCEISENIPGKWTKNG-LPVQESDRLKVVHKGRIHKLVIANALTEDEGDY-VFAPDAYN 534
            L CE+++     W K+G + V++  R+     G +  L I +A   D G Y V   +A N
Sbjct: 4860 LSCELNKERDVVWRKDGKIVVEKPGRIVPGVIGLMRALTINDADDTDAGTYTVTVENANN 4919

Query: 535  VTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEG 594
            +   + V V++   +I D L        +      +      +  P   W +G   I   
Sbjct: 4920 LECSSCVKVVE---VIRDWLVKPIRDQHVKPKGTAIFACDIAKDTPNIKWFKGYDEI-PA 4975

Query: 595  SGRIRTESYPDSSTLVIDI--AERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPT 652
                +TE   D + L + I  A  +D   Y + ++ +   A  ++  + V+   P    T
Sbjct: 4976 EPNDKTEILRDGNHLYLKIKNAMPEDIAEYAVEIEGKRYPAKLTLGEREVELLKPIEDVT 5035

Query: 653  VTE 655
            + E
Sbjct: 5036 IYE 5038



 Score = 63.5 bits (153), Expect = 1e-09
 Identities = 31/92 (33%), Positives = 43/92 (46%)

Query: 1054 PMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEI 1113
            P     L N   I G + TL C + G P P +TW +    I     +++    G+  L I
Sbjct: 897  PTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLMI 956

Query: 1114 RKPSPYDGGTYCCKAVNDLGTVEIECKLEVKV 1145
            R+    D G + C AVN+ GTV   C L V+V
Sbjct: 957  REAFAEDSGRFTCSAVNEAGTVSTSCYLAVQV 988



 Score = 61.2 bits (147), Expect = 5e-09
 Identities = 33/100 (33%), Positives = 54/100 (54%), Gaps = 6/100 (6%)

Query: 938   RPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEH-YHRTS 996
             RP PP++ K+     E + + W PP+ DG  +ITGY ++K +K S  W  V +       
Sbjct: 12026 RPDPPEVTKVSK---EEMTVVWNPPEYDGGKSITGYFLEKKEKHSTRWVPVNKSAIPERR 12082

Query: 997   ATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARD 1036
               +  L+  +EY FRV +EN  G+ E +  ++   V+A+D
Sbjct: 12083 MKVQNLLPDHEYQFRVKAENEIGIGEPSLPSR--PVVAKD 12120



 Score = 59.7 bits (143), Expect = 2e-08
 Identities = 74/324 (22%), Positives = 129/324 (39%), Gaps = 19/324 (5%)

Query: 836  LVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQ--GKPRPELTWKKDGAEID----- 888
            L +E   P +   P  + +  ++++ E  ++V   Q  G P+P + WKK G  +      
Sbjct: 1023 LTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRY 1082

Query: 889  KNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIE 948
            K   N +  E   +I +  A+   +G+Y + V+ +K  ET S    +++      ++K +
Sbjct: 1083 KVSYNKQTGECKLVISMTFAD--DAGEYTIVVR-NKHGET-SASASLLEEADYELLMKSQ 1138

Query: 949  DVWGENVALTWTPPKDDGNAAITGYTIQKADKK-SMEWFTVIEHYHRTSATITELVIGNE 1007
                    +T    +        G+   + +K+   E   + +   + +  +   V   E
Sbjct: 1139 QEMLYQTQVTAFVQEPKVGETAPGFVYSEYEKEYEKEQALIRKKMAKDTVVVRTYVEDQE 1198

Query: 1008 YYFRVFSENMCGLSEDATM-TKESAVIARDGKIYKNPVYEDFDFSEAPM--FTQPLVNTY 1064
            ++   F E +    E   + T    ++  DG+     +  D   SEA    F   + N  
Sbjct: 1199 FHISSFEERLIKEIEYRIIKTTLEELLEEDGE---EKMAVDISESEAVESGFDSRIKNYR 1255

Query: 1065 AIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRM-FSNQGVCTLEIRKPSPYDGGT 1123
             + G   T +C + G P PKI W K+   I    RY+M F   G  +L I    P D G 
Sbjct: 1256 ILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPEDEGI 1315

Query: 1124 YCCKAVNDLGTVEIECKLEVKVIA 1147
            Y   A N  G      KL V+  A
Sbjct: 1316 YTAFASNIKGNAICSGKLYVEPAA 1339



 Score = 57.0 bits (136), Expect = 1e-07
 Identities = 43/167 (25%), Positives = 72/167 (43%), Gaps = 11/167 (6%)

Query: 370 TKQLEDTTAYCGERVELECEVSEDDA-NVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIE 428
           T+ L+      G     E  +S      V WF++G+ I        +I     +  L I 
Sbjct: 9   TQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKLTIP 68

Query: 429 GATKADAAEYSVMTTGGQSSAKLSVDL------KPLKILTPLTDQTVNLGKEICLKCEIS 482
             TKA++  YS+  T G   A  + +L       P   +  L   TV  G ++ L+  ++
Sbjct: 69  AVTKANSGRYSLKATNGSGQATSTAELLVKAETAPPNFVQRLQSMTVRQGSQVRLQVRVT 128

Query: 483 ENIPG---KWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDY 526
             IP    K+ ++G  +Q S   ++  +G ++ L+IA A  ED G Y
Sbjct: 129 -GIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTY 174



 Score = 56.6 bits (135), Expect = 1e-07
 Identities = 39/140 (27%), Positives = 56/140 (40%), Gaps = 9/140 (6%)

Query: 1010  FRVFSENMCGLSEDATM---TKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAI 1066
             F+   E +  +SE       T ES V  +       P+      S  P+    L +T   
Sbjct: 26439 FKSIHEKVSKISETKKSDQKTTESTVTRKTEPKAPEPI------SSKPVIVTGLQDTTVS 26492

Query: 1067  AGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCC 1126
             +   A       G P+P   W K+  AI    +Y++  ++G   LEI K    D G Y C
Sbjct: 26493 SDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTC 26552

Query: 1127  KAVNDLGTVEIECKLEVKVI 1146
                N  G+V   CKL +K I
Sbjct: 26553 TVKNSAGSVSSSCKLTIKAI 26572



 Score = 56.6 bits (135), Expect = 1e-07
 Identities = 74/348 (21%), Positives = 121/348 (34%), Gaps = 77/348 (22%)

Query: 872   GKPRPELTWKKDGAEIDKN-QINIRNSETDTIIFIRKAERSHSGKYD------------- 917
             G+PRP   W KDG  I +  +  +   +    + I K + S SG Y              
Sbjct: 26505 GEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSS 26564

Query: 918   --LQVKVDKFVETASIDIQIIDRPGPPQIVKIED------VWGENVALTWTPP------K 963
               L +K  K  E   +  Q      P +   +++      +  E + ++          K
Sbjct: 26565 CKLTIKAIKDTEAQKVSTQKTSEITPQKKAVVQEEISQKALRSEEIKMSEAKSQEKLALK 26624

Query: 964   DDGNAAITGYTIQKADKKSMEWFTVIEHYHRTS-------------ATITELVIGNEYYF 1010
             ++ +  +    ++K+   S+E   V E   +TS             A  T++ I NE   
Sbjct: 26625 EEASKVLISEEVKKSAATSLEKSIVHEEITKTSQASEEVRTHAEIKAFSTQMSI-NEGQR 26683

Query: 1011  RVFSENMCGLSE-----------------------DATMT------KESAVIARDGKIYK 1041
              V   N+ G ++                       D T+T      ++  ++    K  +
Sbjct: 26684 LVLKANIAGATDVKWVLNGVELTNSEEYRYGVSGSDQTLTIKQASHRDEGILTCISKTKE 26743

Query: 1042  NPVYEDFDF------SEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIV 1095
               V   +D       S+AP F     +     G N    C + G P P+I W KN + I 
Sbjct: 26744 GIVKCQYDLTLSKELSDAPAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPIS 26803

Query: 1096  DDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1143
                   +  ++ V +LEIR  S  D G Y  KA N  G       L V
Sbjct: 26804 ISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMV 26851



 Score = 54.7 bits (130), Expect = 5e-07
 Identities = 52/221 (23%), Positives = 77/221 (34%), Gaps = 45/221 (20%)

Query: 927  ETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWF 986
            +TA  D++++ RP P      E  W             DG   +  YT +          
Sbjct: 1426 QTARFDLKVVGRPMP------ETFWFH-----------DGQQIVNDYTHK---------- 1458

Query: 987  TVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYE 1046
             VI+     S  I      +   + V ++N  G S  + +    AV              
Sbjct: 1459 VVIKEDGTQSLIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAV-------------- 1504

Query: 1047 DFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDD--PRYRMFS 1104
              +    PMF + L N     G    +     GNP P I W+KN   IV    P+ R+  
Sbjct: 1505 --EHQVKPMFVEKLKNVNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEG 1562

Query: 1105 NQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVKV 1145
             +G   L+I      D   Y   A+N  G     CK+ V+V
Sbjct: 1563 TKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEV 1603



 Score = 52.8 bits (125), Expect = 2e-06
 Identities = 86/414 (20%), Positives = 162/414 (39%), Gaps = 69/414 (16%)

Query: 288  QVDKGGRVRFVVELAD-PKLEVKWYKNGQEIRPSTKYIF--EHKGCQRILFINNCQMTDD 344
            +V  G  VRF   ++  PK E++W+ N Q I P+   +F  E      ++ I +      
Sbjct: 3429 RVHNGETVRFHARVSGIPKPEIQWFHNQQLILPTKDVVFHFEESTGMALMLIVDAYSEHA 3488

Query: 345  SEYYV----TAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWF 400
             +Y      +AG+  C+  L        VT +  ++  +  ER+E E E+   + +  + 
Sbjct: 3489 GQYSCKAANSAGEATCAATL-------TVTPKAPESILH--ERIEQEIEMEMKEFSSSFL 3539

Query: 401  KNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKI 460
               EE +   + +   ++     +L          +E  V  T   S  + +  +     
Sbjct: 3540 SAEEEGLHSAELQLS-KINETLELL----------SESPVYPTKFDSEKEGTGPI----F 3584

Query: 461  LTPLTDQTVNLGKEICLKCEISENIPG---KWTKNGLPVQESDRLKVVHKGRIHKLVIAN 517
            +  +++  +++G    L   +   IP    +W  NG+ +  S   K V  G  H L+I  
Sbjct: 3585 IKEVSNADISMGDVATLSVTVI-GIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLIILF 3643

Query: 518  ALTEDEGDYV-FAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRL------ 570
               EDEG+Y   A + Y  T+ +    I+      +G     T + +A +  +L      
Sbjct: 3644 TKLEDEGEYTCMASNDYGKTICSAYLKINSKG---EGHKDTETESAVAKSLEKLGGPCPP 3700

Query: 571  -------------------EIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVI 611
                               E  + GEP P   W + +K +          +   S T ++
Sbjct: 3701 HFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIV 3760

Query: 612  DIAERDDSGVYHINLKNEAGEAHASIKVKVV----DFPDPPV-APTVTEVGDDW 660
            +  +R+DSG+Y    +N  GE+  + ++ V+    D  D P  A +  E  +D+
Sbjct: 3761 NDPQREDSGLYICKAENMLGESTCAAELLVLLEDTDMTDTPCKAKSTPEAPEDF 3814



 Score = 51.2 bits (121), Expect = 6e-06
 Identities = 56/305 (18%), Positives = 122/305 (40%), Gaps = 22/305 (7%)

Query: 849   PRHLKQTYIRRVGEAVNLVIPFQ--GKPRPELTWKKDGAEID-KNQINIRNSETDTIIFI 905
             P  + Q   + + E  N++   +  G+P PE+ W K+   I   + ++I  S     + I
Sbjct: 26762 PAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEI 26821

Query: 906   RKAERSHSGKYDLQVKVDKFVETASIDIQIIDR-PGPPQIVKIEDVWGENVALTWTPPKD 964
             R A  S SGKY ++ K  +   +A+  + ++     P + V +      ++  +++    
Sbjct: 26822 RNASVSDSGKYTIKAKNFRGQCSATASLMVLPLVEEPSREVVLRTSGDTSLQGSFSSQSV 26881

Query: 965   DGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDA 1024
               +A+    +       S    T ++    ++ +++ +    E +  + S +  G+S   
Sbjct: 26882 QMSASKQEASFSSFSSSSASSMTEMKFASMSAQSMSSM---QESFVEMSSSSFMGISNMT 26938

Query: 1025  TMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAI-AGYNATLNCSVRGNPKP 1083
              +   ++ + + G                P   + L +  +I  G   T+ C+  G P P
Sbjct: 26939 QLESSTSKMLKAG------------IRGIPPKIEALPSDISIDEGKVLTVACAFTGEPTP 26986

Query: 1084  KITWM--KNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKL 1141
             ++TW     K+   +  R+ + +   + TL I      DGG Y     N+ G+      +
Sbjct: 26987 EVTWSCGGRKIHSQEQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNI 27046

Query: 1142  EVKVI 1146
              ++ I
Sbjct: 27047 HIRSI 27051



 Score = 49.7 bits (117), Expect = 2e-05
 Identities = 96/424 (22%), Positives = 163/424 (38%), Gaps = 79/424 (18%)

Query: 739  PLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLID 798
            PLA+     LL  +   +  +     PPD I  +  +   ++   E      V  +DL+ 
Sbjct: 4093 PLALEEKQVLLKEEHSDNVVM-----PPDQIIESKREPVAIKKVQE------VQGRDLLS 4141

Query: 799  KTKFTITGLPTDAKIFVRV---KAVNAAGASE-PKYYSQPILVKEIIEPPKIRI---PRH 851
            K    ++G+P + ++ +++   +A+ AA ASE P  +S+ +   E +E   + I   PRH
Sbjct: 4142 KESL-LSGIPEEQRLNLKIQICRALQAAVASEQPGLFSEWLRNIEKVEVEAVNITQEPRH 4200

Query: 852  LKQTYI----RRVGEAVNLVIPFQGKPRPELTWKKDGA--EIDKNQINIRNSETDTIIFI 905
            +   Y+    + V E V ++I         L  +   A   I   +I+I  +E   I   
Sbjct: 4201 IMCMYLVTSAKSVTEEVTIIIEDVDPQMANLKMELRDALCAIIYEEIDILTAEGPRI--- 4257

Query: 906  RKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVA-----LTWT 960
                     K  LQ ++D F  +  ++           ++  E+V   NV      L  T
Sbjct: 4258 -----QQGAKTSLQEEMDSFSGSQKVEPITEPEVESKYLISTEEVSYFNVQSRVKYLDAT 4312

Query: 961  PPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGL 1020
            P      +A+       +D+K  E     E    +S+                     G 
Sbjct: 4313 PVTKGVASAVV------SDEKQDESLKPSEEKEESSSE-------------------SGT 4347

Query: 1021 SEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGN 1080
             E AT+  + A    +G + K          + PM   PLV+T +  G    L  S+  N
Sbjct: 4348 EEVATVKIQEA----EGGLIKE---------DGPMIHTPLVDTVSEEGDIVHLTTSIT-N 4393

Query: 1081 PKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDG-GTYCCKAVNDLGTVEIEC 1139
             K ++ W      +  D +++   +Q   TL I K +  D  G Y C+A+ND G      
Sbjct: 4394 AK-EVNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDHQGEYVCEALNDSGKTATSA 4452

Query: 1140 KLEV 1143
            KL V
Sbjct: 4453 KLTV 4456



 Score = 48.9 bits (115), Expect = 3e-05
 Identities = 59/283 (20%), Positives = 97/283 (34%), Gaps = 70/283 (24%)

Query: 861  GEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQV 920
            GE+V L     G P P +TW ++  +I+                                
Sbjct: 911  GESVTLECHISGYPSPTVTWYREDYQIE-------------------------------- 938

Query: 921  KVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADK 980
                    +SID QI  + G  +++  E    ++   T +   + G  + + Y   +   
Sbjct: 939  --------SSIDFQITFQSGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQ--- 987

Query: 981  KSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIY 1040
                   V E + + +  +TE     E   + F E+   +  D ++T+E A        Y
Sbjct: 988  -------VSEEFEKETTAVTEKFTTEE---KRFVESRDVVMTDTSLTEEQAGPGEPAAPY 1037

Query: 1041 KNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRY 1100
                            T+P+V    + G +    C V GNPKP + W K+ V +    RY
Sbjct: 1038 --------------FITKPVVQKL-VEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRY 1082

Query: 1101 RMFSNQ--GVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKL 1141
            ++  N+  G C L I      D G Y     N  G       L
Sbjct: 1083 KVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL 1125



 Score = 47.4 bits (111), Expect = 8e-05
 Identities = 28/96 (29%), Positives = 44/96 (45%), Gaps = 2/96 (2%)

Query: 1051 SEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDD--PRYRMFSNQGV 1108
            ++AP FTQPL +   + G  AT    + G P P+++W ++   I     P  ++  + G 
Sbjct: 3    TQAPTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGR 62

Query: 1109 CTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVK 1144
              L I   +  + G Y  KA N  G      +L VK
Sbjct: 63   AKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVK 98



 Score = 47.0 bits (110), Expect = 1e-04
 Identities = 64/324 (19%), Positives = 119/324 (36%), Gaps = 26/324 (8%)

Query: 842  EPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKN-QINIRNSETD 900
            EPP++   + L+   ++  G+         G+P+P+++W K+   +    +    +   +
Sbjct: 3191 EPPQVL--QELQPVTVQS-GKPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQE 3247

Query: 901  TIIFIRKAERSHSGKYDLQVKVDKFVET--ASIDIQIIDRPGPPQ---------IVKIED 949
              + + +A    +  Y  + K D  V T  AS+ +++ +   P Q         I  ++D
Sbjct: 3248 YTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMPVYPPAIITPLQD 3307

Query: 950  -VWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEY 1008
             V  E     +       +  ++ Y+  K  K S  +F + +        I E    +E 
Sbjct: 3308 TVTSEGQPARFQCRVSGTDLKVSWYSKDKKIKPS-RFFRMTQFEDTYQLEIAEAYPEDEG 3366

Query: 1009 YFRVFSENMCG-------LSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLV 1061
             +   + N  G       LS +     E         +  +  ++     + P F QPL 
Sbjct: 3367 TYTFVASNAVGQVSSTANLSLEGFSKFEENTSNSQWHVSLSVSFKKEPLGQKPSFIQPLS 3426

Query: 1062 NTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIV--DDPRYRMFSNQGVCTLEIRKPSPY 1119
            +     G     +  V G PKP+I W  N+  I+   D  +    + G+  + I      
Sbjct: 3427 SLRVHNGETVRFHARVSGIPKPEIQWFHNQQLILPTKDVVFHFEESTGMALMLIVDAYSE 3486

Query: 1120 DGGTYCCKAVNDLGTVEIECKLEV 1143
              G Y CKA N  G       L V
Sbjct: 3487 HAGQYSCKAANSAGEATCAATLTV 3510



 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 36/105 (34%), Positives = 48/105 (45%), Gaps = 4/105 (3%)

Query: 537 LPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSG 596
           +PA V +   P  ++ GL     VTVI G  + LE  ISG P P   W R D  I E S 
Sbjct: 886 VPAPVEIPVTPPTLVSGL---KNVTVIEGESVTLECHISGYPSPTVTWYREDYQI-ESSI 941

Query: 597 RIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKV 641
             +       + L+I  A  +DSG +  +  NEAG    S  + V
Sbjct: 942 DFQITFQSGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAV 986



 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 29/93 (31%), Positives = 42/93 (45%), Gaps = 3/93 (3%)

Query: 1054  PMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIV---DDPRYRMFSNQGVCT 1110
             P FT PL N  A  G N     ++  +P+P +TW K+   I    +D +Y   S++G+  
Sbjct: 25318 PEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQ 25377

Query: 1111  LEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1143
             L I   +  D   Y   A N  G    + KL V
Sbjct: 25378 LTINSVTTDDDAEYTVVARNKYGEDSCKAKLTV 25410



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 34/107 (31%), Positives = 47/107 (43%), Gaps = 4/107 (3%)

Query: 1041 KNPVYEDFDFSE----APMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVD 1096
            ++PVY     SE     P+F + + N     G  ATL+ +V G PKPKI W  N V +  
Sbjct: 3565 ESPVYPTKFDSEKEGTGPIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTP 3624

Query: 1097 DPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1143
               Y+   +    +L I      D G Y C A ND G       L++
Sbjct: 3625 SADYKFVFDGDDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKI 3671



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 25/93 (26%), Positives = 42/93 (45%)

Query: 1053 APMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLE 1112
            AP+  + +       G+ A   C ++  P  +  W K    I +  +  + S++ + +LE
Sbjct: 4461 APVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLE 4520

Query: 1113 IRKPSPYDGGTYCCKAVNDLGTVEIECKLEVKV 1145
            I +    D G Y CKA N+ G+V     L V V
Sbjct: 4521 ILRTQVVDCGEYTCKASNEYGSVSCTATLTVTV 4553



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 30/96 (31%), Positives = 39/96 (40%), Gaps = 3/96 (3%)

Query: 1054 PMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSN-QGVCTLE 1112
            P F + L       G  A    +V G P P +TW K    +     Y +  N  G  T  
Sbjct: 3700 PHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFI 3759

Query: 1113 IRKPSPYDGGTYCCKAVNDLGTVEIECKLEVKVIAQ 1148
            +  P   D G Y CKA N LG  E  C  E+ V+ +
Sbjct: 3760 VNDPQREDSGLYICKAENMLG--ESTCAAELLVLLE 3793



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 29/100 (29%), Positives = 49/100 (49%), Gaps = 5/100 (5%)

Query: 939   PGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEH--YHRTS 996
             P  P    + +V  ++  +TW  P D G   IT Y ++K +  S  W  V +   +  T 
Sbjct: 10640 PDAPDQPIVTEVTKDSALVTWNKPHDGGKP-ITNYILEKRETMSKRWARVTKDPIHPYTK 10698

Query: 997   ATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARD 1036
               + +L+ G +Y FRV +EN  G+ + +  +K   V A+D
Sbjct: 10699 FRVPDLLEGCQYEFRVSAENEIGIGDPSPPSK--PVFAKD 10736



 Score = 45.1 bits (105), Expect = 4e-04
 Identities = 120/582 (20%), Positives = 208/582 (35%), Gaps = 92/582 (15%)

Query: 341  MTDDSEYYVTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDA-NVKW 399
            MTD S     AG  + +   F+ +P  +V K +E      G  V   C+V  +   +V W
Sbjct: 1018 MTDTSLTEEQAGPGEPAAPYFITKP--VVQKLVE------GGSVVFGCQVGGNPKPHVYW 1069

Query: 400  FKNGEEIIPGPKSRYRIRVEGKKHI----LIIEGATKADAAEYSVMTTG--GQSSAKLSV 453
             K+G  +  G    YR +V   K      L+I      DA EY+++     G++SA  S+
Sbjct: 1070 KKSGVPLTTG----YRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL 1125

Query: 454  DLKPLKILTPLTDQTVNLGKEICL---KCEISENIPGKWTKNGLPVQESDRLKVVHKGRI 510
              +    L   + Q +    ++     + ++ E  PG +  +    +      ++ K   
Sbjct: 1126 LEEADYELLMKSQQEMLYQTQVTAFVQEPKVGETAPG-FVYSEYEKEYEKEQALIRKKMA 1184

Query: 511  HKLVIANALTEDEGDYVFAPDA----------YNVTLPAKVHVIDPPKIILD-------- 552
               V+     ED+  ++ + +              TL   +      K+ +D        
Sbjct: 1185 KDTVVVRTYVEDQEFHISSFEERLIKEIEYRIIKTTLEELLEEDGEEKMAVDISESEAVE 1244

Query: 553  -GLDAD-NTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDS-STL 609
             G D+      ++ G  +     +SG P PK  W +  K I  G  R + +   D  ++L
Sbjct: 1245 SGFDSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGE-RYQMDFLQDGRASL 1303

Query: 610  VIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPA 669
             I +   +D G+Y     N  G A  S K+ V      P AP    +G    I   EP  
Sbjct: 1304 RIPVVLPEDEGIYTAFASNIKGNAICSGKLYV-----EPAAP----LGAPTYIPTLEP-- 1352

Query: 670  YDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISK 729
                       + R +  S R +  +          P +M        R+     +  + 
Sbjct: 1353 -----------VSRIRSLSPRSVSRSPIRMSPARMSPARMSPARMSPARMSPGRRLEETD 1401

Query: 730  PSMPSRPFVPLAVTSPPTLLTVDSVT---DTTVTMRWRPPD---HIGAAGLDGYVLEYCF 783
             S   R + P+ V  P +   ++  T   D  V  R  P     H G   ++ Y  +   
Sbjct: 1402 ESQLERLYKPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVI 1461

Query: 784  --EGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEII 841
              +GT+  I+      D  ++T+              A N AG S     S  + V+ + 
Sbjct: 1462 KEDGTQSLIIVPATPSDSGEWTVV-------------AQNRAGRSS---ISVILTVEAVE 1505

Query: 842  EPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKD 883
               K      LK   I+  G  + + +   G P P++ W K+
Sbjct: 1506 HQVKPMFVEKLKNVNIKE-GSRLEMKVRATGNPNPDIVWLKN 1546



 Score = 44.7 bits (104), Expect = 5e-04
 Identities = 62/284 (21%), Positives = 105/284 (36%), Gaps = 51/284 (17%)

Query: 876  PELT--WKKDGAEID-KNQINIRNSETDTIIFIRKAERSHSGKYDL----QVKVDK-FVE 927
            P++T  W KD  E+   ++I I+  +    + I     S +GKY +     V   K FVE
Sbjct: 3038 PDITVQWMKDDQELQITDRIKIQKEKYVHRLLIPSTRMSDAGKYTVVAGGNVSTAKLFVE 3097

Query: 928  TASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNA------AITGYTIQKADKK 981
               + I+ I +       +++ +  +   + +   +DD +A          + +Q+  K 
Sbjct: 3098 GRDVRIRSIKK-------EVQVIEKQRAVVEFEVNEDDVDAHWYKDGIEINFQVQERHK- 3149

Query: 982  SMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYK 1041
                + V    HR   + T      EY F V   N   ++                 +Y 
Sbjct: 3150 ----YVVERRIHRMFISETRQSDAGEYTF-VAGRNRSSVT-----------------LYV 3187

Query: 1042 NPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYR 1101
            N         E P   Q L      +G  A     + G P+PKI+W K +  +    + +
Sbjct: 3188 NA-------PEPPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCK 3240

Query: 1102 MFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVKV 1145
               +    TL + +  P D   Y C+A ND G       L V+V
Sbjct: 3241 FLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEV 3284



 Score = 44.3 bits (103), Expect = 7e-04
 Identities = 29/98 (29%), Positives = 51/98 (52%), Gaps = 1/98 (1%)

Query: 559 TVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDD 618
           ++TV  G+++RL++ ++G P P   + R D A ++ S   +     D  +L+I  A  +D
Sbjct: 112 SMTVRQGSQVRLQVRVTGIPTPVVKFYR-DGAEIQSSLDFQISQEGDLYSLLIAEAYPED 170

Query: 619 SGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEV 656
           SG Y +N  N  G A ++ ++ V    + P   T T V
Sbjct: 171 SGTYSVNATNSVGRATSTAELLVQGEEEVPAKKTKTIV 208



 Score = 44.3 bits (103), Expect = 7e-04
 Identities = 64/320 (20%), Positives = 110/320 (34%), Gaps = 40/320 (12%)

Query: 340   QMTDDSEYYVTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEV-SEDDANVK 398
             Q T + +Y      E  S + F  +    +T ++      CG+       V S+  A VK
Sbjct: 25981 QKTSERKY------EVLSQQPFTLDHAPRITLRMRSHRVPCGQNTRFILNVQSKPTAEVK 26034

Query: 399   WFKNGEEIIPGPKSRYRIRVEGKKHILIIEGAT-------------KADAAEYSVM-TTG 444
             W+ NG E+    K  Y     G   + I++  T             K +A++Y+ +  TG
Sbjct: 26035 WYHNGVELQESSKIHYT-NTSGVLTLEILDCHTDDSGTYRAVCTNYKGEASDYATLDVTG 26093

Query: 445   GQSSAKLSV---DLKPLKILTPLTDQTVNLGKEICLKCEISENIPGKWTKNGLPVQESDR 501
             G  +   S    +  P  +   LT              E+  +   +  K+ +       
Sbjct: 26094 GDYTTYASQRRDEEVPRSVFPELTRTEAYAVSSFKKTSEMEASSSVREVKSQMTETRESL 26153

Query: 502   LKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVT 561
                 H       + + AL E   +          TL A++            L    ++T
Sbjct: 26154 SSYEHSASAE--MKSAALEEKSLEEKSTTRKIKTTLAARI------------LTKPRSMT 26199

Query: 562   VIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGV 621
             V  G   R      GEP P   W R  + ++  S R +  +    ST  I   +  D G 
Sbjct: 26200 VYEGESARFSCDTDGEPVPTVTWLRKGQ-VLSTSARHQVTTTKYKSTFEISSVQASDEGN 26258

Query: 622   YHINLKNEAGEAHASIKVKV 641
             Y + ++N  G+  A   + +
Sbjct: 26259 YSVVVENSEGKQEAEFTLTI 26278



 Score = 43.9 bits (102), Expect = 9e-04
 Identities = 94/440 (21%), Positives = 160/440 (36%), Gaps = 71/440 (16%)

Query: 271  REEKKSAAFAKILDPAYQVDKGGRVRFVVELAD-PKLEVKWYKNGQEIRPSTKYIFEHKG 329
            ++EK+        +P  +V +G   RF   +   P+ +V WY NGQ IR S ++   + G
Sbjct: 1789 QKEKQKPDIVLYPEPV-RVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRVRYDG 1847

Query: 330  CQRILFINNCQMTDDSEYYVTAG------DEKCSTELFVREP------------------ 365
                L I +C+  D  E  VTA       + K   E+  RE                   
Sbjct: 1848 I-HYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQREDFRSVLRRAPEPRPEFHVH 1906

Query: 366  --------------PIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGE-----EI 406
                          P+  T+  E       ER+  E    E +     FK        E 
Sbjct: 1907 EPGKLQFEVQKVDRPVDTTETKEVVKLKRAERITHEKVPEESEELRSKFKRRTEEGYYEA 1966

Query: 407  IPGPKSRYRIRVEGKKHIL-------------IIEGATKADAAEYSV-MTTGGQSSAKLS 452
            I   + + R + E  + +L             + E   KA A E  + + T      +LS
Sbjct: 1967 ITAVELKSRKKDESYEELLRKTKDELLHWTKELTEEEKKALAEEGKITIPTFKPDKIELS 2026

Query: 453  VDLKPLKILTPLTDQTVNLGKEICLKCEI--SENIPGKWTKNGLPVQESDRLK-VVHKGR 509
              ++  KI   +  QTV  G +   +  +    +   +W KNG+ ++ SDR+     +  
Sbjct: 2027 PSMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDN 2086

Query: 510  IHKLVIANALTEDEGDYVFAPDAYNVTLPAKVH---VIDPPKIILDGLDADNTVTVIAGN 566
            + +LVI +   ED    +    A N+      H   ++   ++I    +  + V      
Sbjct: 2087 VCELVIRDVTAEDSASIMV--KAINIAGETSSHAFLLVQAKQLITFTQELQDVVAKEKDT 2144

Query: 567  KLRLEIPISGEPPPKAMWSRGDKAIMEGSG-RIRTE-SYPDSSTLVIDIAERDDSGVYHI 624
                E   S EP  K  W +    + EG   R+ ++      S L ID ++ +D     +
Sbjct: 2145 MATFECETS-EPFVKVKWYKDGMEVHEGDKYRMHSDRKVHFLSILTIDTSDAEDYSCVLV 2203

Query: 625  NLKNEAGEAHASIKVKVVDF 644
              +N    A   ++  VV+F
Sbjct: 2204 EDENVKTTAKLIVEGAVVEF 2223



 Score = 43.9 bits (102), Expect = 9e-04
 Identities = 26/79 (32%), Positives = 37/79 (46%), Gaps = 1/79 (1%)

Query: 1066 IAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYC 1125
            + G  A   C V G P+PK+ W  N   I    R+R+    G+  L+I     YD G   
Sbjct: 1807 LEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRV-RYDGIHYLDIVDCKSYDTGEVK 1865

Query: 1126 CKAVNDLGTVEIECKLEVK 1144
              A N  G +E + KLE++
Sbjct: 1866 VTAENPEGVIEHKVKLEIQ 1884



 Score = 43.9 bits (102), Expect = 9e-04
 Identities = 59/286 (20%), Positives = 102/286 (35%), Gaps = 24/286 (8%)

Query: 861   GEAVNLVIPFQGKPRPELTWKKDGAEI-DKNQINIRNSETDTIIFIRKAERSHSGKYDLQ 919
             G+    ++  Q KP  E+ W  +G E+ + ++I+  N+     + I       SG Y  +
Sbjct: 26016 GQNTRFILNVQSKPTAEVKWYHNGVELQESSKIHYTNTSGVLTLEILDCHTDDSGTY--R 26073

Query: 920   VKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKAD 979
                  +   AS D   +D  G            E V  +  P      A    Y +    
Sbjct: 26074 AVCTNYKGEAS-DYATLDVTGGDYTTYASQRRDEEVPRSVFPELTRTEA----YAVSSFK 26128

Query: 980   KKS-MEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGK 1038
             K S ME  + +       + +TE             E++      A+   +SA +     
Sbjct: 26129 KTSEMEASSSVRE---VKSQMTET-----------RESLSSYEHSASAEMKSAALEEKSL 26174

Query: 1039  IYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDP 1098
               K+   +      A + T+P   T    G +A  +C   G P P +TW++    +    
Sbjct: 26175 EEKSTTRKIKTTLAARILTKPRSMT-VYEGESARFSCDTDGEPVPTVTWLRKGQVLSTSA 26233

Query: 1099  RYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVK 1144
             R+++ + +   T EI      D G Y     N  G  E E  L ++
Sbjct: 26234 RHQVTTTKYKSTFEISSVQASDEGNYSVVVENSEGKQEAEFTLTIQ 26279



 Score = 43.5 bits (101), Expect = 0.001
 Identities = 61/263 (23%), Positives = 104/263 (39%), Gaps = 35/263 (13%)

Query: 286   AYQVDKGGRVRFVVEL-ADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDD 344
             +++V  G   RF++ + + P  EVKWY NG E++ S+K  + +      L I +C  TDD
Sbjct: 26010 SHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESSKIHYTNTSGVLTLEILDCH-TDD 26068

Query: 345   SEYY------------------VTAGD-EKCSTELFVREPPIMVTKQLEDTTAYCGERVE 385
             S  Y                  VT GD    +++    E P  V  +L  T AY     +
Sbjct: 26069 SGTYRAVCTNYKGEASDYATLDVTGGDYTTYASQRRDEEVPRSVFPELTRTEAYAVSSFK 26128

Query: 386   LECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGG 445
                E+ E  ++V+  K+         +  R  +   +H      + +  +A     +   
Sbjct: 26129 KTSEM-EASSSVREVKS-------QMTETRESLSSYEH----SASAEMKSAALEEKSLEE 26176

Query: 446   QSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCEI-SENIPG-KWTKNGLPVQESDRLK 503
             +S+ +        +ILT     TV  G+     C+   E +P   W + G  +  S R +
Sbjct: 26177 KSTTRKIKTTLAARILTKPRSMTVYEGESARFSCDTDGEPVPTVTWLRKGQVLSTSARHQ 26236

Query: 504   VVHKGRIHKLVIANALTEDEGDY 526
             V          I++    DEG+Y
Sbjct: 26237 VTTTKYKSTFEISSVQASDEGNY 26259



 Score = 43.1 bits (100), Expect = 0.002
 Identities = 41/170 (24%), Positives = 67/170 (39%), Gaps = 16/170 (9%)

Query: 489  WTKNGLPVQESDRLKVVHK-GRIHKLVIANALTEDEGDYVFAPD--------AYNVTLPA 539
            W  +G  +      KVV K      L+I  A   D G++             +  +T+ A
Sbjct: 1444 WFHDGQQIVNDYTHKVVIKEDGTQSLIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEA 1503

Query: 540  KVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGS-GRI 598
              H + P  +     +    V +  G++L +++  +G P P  +W +    I+     +I
Sbjct: 1504 VEHQVKPMFV-----EKLKNVNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKI 1558

Query: 599  RTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKV-VDFPDP 647
            R E     + L ID     DS  Y     N+AG      KV V V+F +P
Sbjct: 1559 RIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEVEFAEP 1608



 Score = 43.1 bits (100), Expect = 0.002
 Identities = 67/327 (20%), Positives = 116/327 (35%), Gaps = 65/327 (19%)

Query: 369   VTKQLEDTTAYCGERVELECEVSEDDAN--VKWFKNGEEIIPGPKSRYRIRVEGKKHILI 426
             V+ Q+       G  V+  C++   D +  V W+    ++    K  Y I  E    IL 
Sbjct: 25198 VSGQIMHAVGEEGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEK--YEITYEDGVAILY 25255

Query: 427   IEGATKADAAEY--SVMTTGGQSSAKLSVDLK---------------------------- 456
             ++  TK D   Y   V+   G+ S+   + +K                            
Sbjct: 25256 VKDITKLDDGTYRCKVVNDYGEDSSYAELFVKGVREVYDYYCRRTMKKIKRRTDTMRLLE 25315

Query: 457   -PLKILTPLTDQTVNLGKEICLKCEISENIPGK--WTKNGLPVQESDRLKVV----HKGR 509
              P +   PL ++T  +G+ +     I+ +      W K+G  ++  D  K       KG 
Sbjct: 25316 RPPEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKG- 25374

Query: 510   IHKLVIANALTEDEGDYV------FAPDAYNVTLPAKVHVIDPP---------KIILDGL 554
             +++L I +  T+D+ +Y       +  D+    L   +H   PP         K +L   
Sbjct: 25375 LYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVTLH--PPPTDSTLRPMFKRLLANA 25432

Query: 555   DADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIA 614
             +         G  +  EI +SG PPP   W +  + +  G          D   L I   
Sbjct: 25433 ECQE------GQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALHIRDT 25486

Query: 615   ERDDSGVYHINLKNEAGEAHASIKVKV 641
               +D+G Y +   N AG       ++V
Sbjct: 25487 LPEDTGYYRVTATNTAGSTSCQAHLQV 25513



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 33/111 (29%), Positives = 46/111 (41%), Gaps = 5/111 (4%)

Query: 1028 KESAVIARDGKI----YKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKP 1083
            +E   +A +GKI    +K    E     EAP   + + +     G +A     V G P P
Sbjct: 2002 EEKKALAEEGKITIPTFKPDKIELSPSMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDP 2061

Query: 1084 KITWMKNKVAIVDDPR-YRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLG 1133
            +  W KN V I    R Y  +    VC L IR  +  D  +   KA+N  G
Sbjct: 2062 ECEWYKNGVKIERSDRIYWYWPEDNVCELVIRDVTAEDSASIMVKAINIAG 2112



 Score = 40.4 bits (93), Expect = 0.010
 Identities = 73/318 (22%), Positives = 115/318 (36%), Gaps = 33/318 (10%)

Query: 838  KEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQ-GKPRPELTWKKDGAEIDKNQINIRN 896
            K  +E   +RI    K+    +V E    V+ F+  +   +  W KDG EI+        
Sbjct: 3093 KLFVEGRDVRIRSIKKEV---QVIEKQRAVVEFEVNEDDVDAHWYKDGIEINFQVQERHK 3149

Query: 897  SETDTII---FIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGE 953
               +  I   FI +  +S +G+Y      ++   T       ++ P PPQ+++      E
Sbjct: 3150 YVVERRIHRMFISETRQSDAGEYTFVAGRNRSSVTL-----YVNAPEPPQVLQ------E 3198

Query: 954  NVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEY---YF 1010
               +T    K     A+    I    +  + W+   E    T      L  G EY     
Sbjct: 3199 LQPVTVQSGKPARFCAV----ISGRPQPKISWYKE-EQLLSTGFKCKFLHDGQEYTLLLI 3253

Query: 1011 RVFSENM----CGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAI 1066
              F E+     C    D  +   SA ++ +     +P  E   +   P    PL +T   
Sbjct: 3254 EAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMPVYP--PAIITPLQDTVTS 3311

Query: 1067 AGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCC 1126
             G  A   C V G    K++W      I     +RM   +    LEI +  P D GTY  
Sbjct: 3312 EGQPARFQCRVSGTDL-KVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTF 3370

Query: 1127 KAVNDLGTVEIECKLEVK 1144
             A N +G V     L ++
Sbjct: 3371 VASNAVGQVSSTANLSLE 3388



 Score = 40.0 bits (92), Expect = 0.013
 Identities = 44/211 (20%), Positives = 95/211 (45%), Gaps = 28/211 (13%)

Query: 270  RREEKKSAAFAKILDPAYQVD-------KGGRVRFVVELAD-PKLEVKWYKNGQEIRP-- 319
            R EE   +   ++  P + +        +G   RF +++   P  E  W+ +GQ+I    
Sbjct: 1396 RLEETDESQLERLYKPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDY 1455

Query: 320  STKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTELFV--------REPPIMVTK 371
            + K + +  G Q ++ +     +D  E+ V A +    + + V         +   M  +
Sbjct: 1456 THKVVIKEDGTQSLIIVP-ATPSDSGEWTVVAQNRAGRSSISVILTVEAVEHQVKPMFVE 1514

Query: 372  QLEDTTAYCGERVELECEVSED-DANVKWFKNGEEIIPGPKSRY-RIRVEGKK--HILII 427
            +L++     G R+E++   + + + ++ W KN + I+P    +Y +IR+EG K    L I
Sbjct: 1515 KLKNVNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVP---HKYPKIRIEGTKGEAALKI 1571

Query: 428  EGATKADAAEY--SVMTTGGQSSAKLSVDLK 456
            +     D+A Y  + +   G+ + +  V+++
Sbjct: 1572 DSTVSQDSAWYTATAINKAGRDTTRCKVNVE 1602



 Score = 39.7 bits (91), Expect = 0.017
 Identities = 25/98 (25%), Positives = 37/98 (37%)

Query: 1046  EDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSN 1105
             + F    AP  T  + +     G N     +V+  P  ++ W  N V + +  +    + 
Sbjct: 25994 QPFTLDHAPRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESSKIHYTNT 26053

Query: 1106  QGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1143
              GV TLEI      D GTY     N  G       L+V
Sbjct: 26054 SGVLTLEILDCHTDDSGTYRAVCTNYKGEASDYATLDV 26091



 Score = 39.3 bits (90), Expect = 0.022
 Identities = 58/327 (17%), Positives = 107/327 (32%), Gaps = 45/327 (13%)

Query: 861  GEAVNLVIPFQGKPRPELTWKKDGAEIDKN---QINIRNSETDTIIFIRKAERSHSGKYD 917
            G+     +   G+P PE  W  DG +I  +   ++ I+   T ++I +  A  S SG++ 
Sbjct: 1425 GQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLIIV-PATPSDSGEWT 1483

Query: 918  L--QVKVDKFVETASIDIQIIDRPGPPQIV----------------KIEDVWGENVALTW 959
            +  Q +  +   +  + ++ ++    P  V                K+      N  + W
Sbjct: 1484 VVAQNRAGRSSISVILTVEAVEHQVKPMFVEKLKNVNIKEGSRLEMKVRATGNPNPDIVW 1543

Query: 960  TPPKD------------DGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNE 1007
                D            +G        I     +   W+T     ++     T   +  E
Sbjct: 1544 LKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATA-INKAGRDTTRCKVNVE 1602

Query: 1008 YYFR--------VFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQP 1059
              F         +         E A    E   +    + ++     D +  + P F + 
Sbjct: 1603 VEFAEPEPERKLIIPRGTYRAKEIAAPELEPLHLRYGQEQWEEGDLYDKEKQQKPFFKKK 1662

Query: 1060 LVNTYAIAGYNATLNCSVR--GNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPS 1117
            L +        A   C +   G+P   + W+ +   +    R RM +  G C+L+     
Sbjct: 1663 LTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRMINEFGYCSLDYGVAY 1722

Query: 1118 PYDGGTYCCKAVNDLGTVEIECKLEVK 1144
              D G   C+A N  GT      L VK
Sbjct: 1723 SRDSGIITCRATNKYGTDHTSATLIVK 1749



 Score = 38.9 bits (89), Expect = 0.028
 Identities = 44/162 (27%), Positives = 69/162 (42%), Gaps = 13/162 (8%)

Query: 304 PKLEVKWYKNGQEIRPST--KYIFEHKGCQRILFINNCQMTDDSEYYVTA----GDEKCS 357
           P  EV W+++GQ I  ST           +  L I      +   Y + A    G    +
Sbjct: 33  PVPEVSWFRDGQVISTSTLPGVQISFSDGRAKLTIPAVTKANSGRYSLKATNGSGQATST 92

Query: 358 TELFVR---EPPIMVTKQLEDTTAYCGERVELECEVSE-DDANVKWFKNGEEIIPGPKSR 413
            EL V+    PP  V ++L+  T   G +V L+  V+      VK++++G EI       
Sbjct: 93  AELLVKAETAPPNFV-QRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEI--QSSLD 149

Query: 414 YRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDL 455
           ++I  EG  + L+I  A   D+  YSV  T     A  + +L
Sbjct: 150 FQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAEL 191



 Score = 38.1 bits (87), Expect = 0.048
 Identities = 38/173 (21%), Positives = 68/173 (39%), Gaps = 11/173 (6%)

Query: 362  VREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGK 421
            ++E   M+   L DT +  G+ V L   ++       +F+N  +++P  + +++   +  
Sbjct: 4363 IKEDGPMIHTPLVDTVSEEGDIVHLTTSITNAKEVNWYFEN--KLVPSDE-KFKCLQDQN 4419

Query: 422  KHILIIEGATKAD-AAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVN-----LGKEI 475
             + L+I+     D   EY             S  L  +K   P+  + +      LG   
Sbjct: 4420 TYTLVIDKVNTEDHQGEYVCEALNDSGKTATSAKLTVVKRAAPVIKRKIEPLEVALGHLA 4479

Query: 476  CLKCEISE--NIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDY 526
               CEI    N+  +W K G  + ESD+  +     I  L I      D G+Y
Sbjct: 4480 KFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEY 4532



 Score = 38.1 bits (87), Expect = 0.048
 Identities = 27/98 (27%), Positives = 41/98 (41%), Gaps = 3/98 (3%)

Query: 1049  DFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGV 1108
             D +  PMF + L N     G +      V G P P + W K+   +   P   +  ++G+
Sbjct: 25418 DSTLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEII-HEGL 25476

Query: 1109  --CTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVK 1144
                 L IR   P D G Y   A N  G+   +  L+V+
Sbjct: 25477 DYYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQVE 25514



 Score = 37.7 bits (86), Expect = 0.063
 Identities = 26/83 (31%), Positives = 34/83 (40%), Gaps = 5/83 (6%)

Query: 289   VDKGGRVRFVVELAD-PKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEY 347
             V  G  VRF   +   P    KW  +G EI+    Y  E      +L I NC   D  EY
Sbjct: 11150 VKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEY 11209

Query: 348   YVT----AGDEKCSTELFVREPP 366
              +T    AG +  +  L V + P
Sbjct: 11210 QITVSNAAGSKTVAVHLTVLDVP 11232



 Score = 37.7 bits (86), Expect = 0.063
 Identities = 19/65 (29%), Positives = 31/65 (47%)

Query: 1084  KITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1143
             ++TW      + +  +Y +    GV  L ++  +  D GTY CK VND G      +L V
Sbjct: 25227 QVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTYRCKVVNDYGEDSSYAELFV 25286

Query: 1144  KVIAQ 1148
             K + +
Sbjct: 25287 KGVRE 25291



 Score = 37.0 bits (84), Expect = 0.11
 Identities = 25/94 (26%), Positives = 40/94 (42%), Gaps = 1/94 (1%)

Query: 1054 PMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYR-MFSNQGVCTLE 1112
            P+F    V+   + G  A  +  V G P P+  W  +   IV+D  ++ +    G  +L 
Sbjct: 1411 PVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLI 1470

Query: 1113 IRKPSPYDGGTYCCKAVNDLGTVEIECKLEVKVI 1146
            I   +P D G +   A N  G   I   L V+ +
Sbjct: 1471 IVPATPSDSGEWTVVAQNRAGRSSISVILTVEAV 1504



 Score = 36.2 bits (82), Expect = 0.18
 Identities = 45/250 (18%), Positives = 92/250 (36%), Gaps = 31/250 (12%)

Query: 880  WKKDGAEIDKN-QINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDR 938
            W KDG EI  + + +I+      I+ I+KA+    G+Y      DK     +++ ++I  
Sbjct: 5322 WFKDGEEIVPSPKYSIKADGLRRILKIKKADLKDKGEYVCDCGTDKTKANVTVEARLIKV 5381

Query: 939  PGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSAT 998
              P   V++      +  +  + P   G   + G  +                   T++ 
Sbjct: 5382 EKPLYGVEVFVGETAHFEIELSEPDVHGQWKLKGQPL-------------------TASP 5422

Query: 999  ITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQ 1058
              E++   + +  +      G++ + +    +A  A + K+ + P+          +F  
Sbjct: 5423 DCEIIEDGKKHILILHNCQLGMTGEVSFQAANAKSAANLKVKELPL----------IFIT 5472

Query: 1059 PLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSP 1118
            PL +        A   C V   PK    W+K    I  D R+ +  +    ++ I+  + 
Sbjct: 5473 PLSDVKVFEKDEAKFECEVSREPK-TFRWLKGTQEITGDDRFELIKDGTKHSMVIKSAAF 5531

Query: 1119 YDGGTYCCKA 1128
             D   Y  +A
Sbjct: 5532 EDEAKYMFEA 5541



 Score = 36.2 bits (82), Expect = 0.18
 Identities = 39/146 (26%), Positives = 56/146 (38%), Gaps = 11/146 (7%)

Query: 301   LADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTEL 360
             L  PK  V W K  Q ++ + +  FE      IL IN C  +D   Y +TA +       
Sbjct: 14718 LGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLTARN------- 14770

Query: 361   FVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEG 420
              V E   ++T Q+ D        ++ + EVS D     W    E     P S Y + +  
Sbjct: 14771 IVGEVGDVITIQVHDIPGPPTGPIKFD-EVSSDFVTFSW-DPPENDGGVPISNYVVEMRQ 14828

Query: 421   KKHILIIEGATKADAAEYSV--MTTG 444
                   +E AT      Y    +TTG
Sbjct: 14829 TDSTTWVELATTVIRTTYKATRLTTG 14854



 Score = 35.8 bits (81), Expect = 0.24
 Identities = 25/91 (27%), Positives = 42/91 (46%), Gaps = 1/91 (1%)

Query: 559 TVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDS-STLVIDIAERD 617
           +V V+ G+    E  ISG P P+  W R  + I   +      S+ D  + L I    + 
Sbjct: 14  SVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKLTIPAVTKA 73

Query: 618 DSGVYHINLKNEAGEAHASIKVKVVDFPDPP 648
           +SG Y +   N +G+A ++ ++ V     PP
Sbjct: 74  NSGRYSLKATNGSGQATSTAELLVKAETAPP 104



 Score = 35.8 bits (81), Expect = 0.24
 Identities = 23/89 (25%), Positives = 34/89 (38%), Gaps = 2/89 (2%)

Query: 561   TVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSG--RIRTESYPDSSTLVIDIAERDD 618
             T   G  +R  + I+  P P   W +  + I  G    +   ES      L I+    DD
Sbjct: 25328 TAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDD 25387

Query: 619   SGVYHINLKNEAGEAHASIKVKVVDFPDP 647
                Y +  +N+ GE     K+ V   P P
Sbjct: 25388 DAEYTVVARNKYGEDSCKAKLTVTLHPPP 25416



 Score = 35.0 bits (79), Expect = 0.41
 Identities = 23/91 (25%), Positives = 37/91 (40%)

Query: 1054 PMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEI 1113
            P F Q L +     G    L   V G P P + + ++   I     +++     + +L I
Sbjct: 104  PNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLI 163

Query: 1114 RKPSPYDGGTYCCKAVNDLGTVEIECKLEVK 1144
             +  P D GTY   A N +G      +L V+
Sbjct: 164  AEAYPEDSGTYSVNATNSVGRATSTAELLVQ 194



 Score = 35.0 bits (79), Expect = 0.41
 Identities = 27/90 (30%), Positives = 39/90 (43%), Gaps = 4/90 (4%)

Query: 1054 PMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEI 1113
            P FT  L +  A+     TL C V  +   K  W K+   IV  P+Y + ++     L+I
Sbjct: 5291 PYFTVKLHDKTAVEKDEITLKCEVSKDVPVK--WFKDGEEIVPSPKYSIKADGLRRILKI 5348

Query: 1114 RKPSPYDGGTYCCKAVND--LGTVEIECKL 1141
            +K    D G Y C    D     V +E +L
Sbjct: 5349 KKADLKDKGEYVCDCGTDKTKANVTVEARL 5378



 Score = 33.9 bits (76), Expect = 0.91
 Identities = 27/119 (22%), Positives = 51/119 (42%), Gaps = 11/119 (9%)

Query: 418 VEGKKHILIIEGATKADAAEYSVM-------TTGGQSSAKLSVDLKPLKILTPLTDQTVN 470
           VE KK + +    T      + V+       T   +  A + + + P  +++ L + TV 
Sbjct: 850 VEVKKEVGVSITGTTVREERFEVLHGREAKVTETARVPAPVEIPVTPPTLVSGLKNVTVI 909

Query: 471 LGKEICLKCEISENIPGK---WTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDY 526
            G+ + L+C IS   P     W +    ++ S   ++  +  I +L+I  A  ED G +
Sbjct: 910 EGESVTLECHIS-GYPSPTVTWYREDYQIESSIDFQITFQSGIARLMIREAFAEDSGRF 967



 Score = 33.9 bits (76), Expect = 0.91
 Identities = 25/77 (32%), Positives = 40/77 (51%), Gaps = 8/77 (10%)

Query: 3    EPTKKEENEVPA-PAPPPEEPSKEKEAGTTPAKDEEEVSPPSALP---PGLGSRALERK- 57
            EP K E+ + PA P PPP +P +E E  T   K E ++  P+ +P   P +   A E K 
Sbjct: 4593 EPKKLEKVKKPAVPEPPPPKPVEEVEVPTV-TKRERKIPEPTKVPEIKPAIPLPAPEPKP 4651

Query: 58   --DSDWTLVETPPGEEQ 72
              +++   ++ PP E +
Sbjct: 4652 KPEAEVKTIKPPPVEPE 4668



 Score = 33.5 bits (75), Expect = 1.2
 Identities = 35/140 (25%), Positives = 63/140 (45%), Gaps = 11/140 (7%)

Query: 799 KTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIR 858
           + K TI  +         +KA N +G +     +  +LVK    PP     + L+   +R
Sbjct: 62  RAKLTIPAVTKANSGRYSLKATNGSGQATS---TAELLVKAETAPPNF--VQRLQSMTVR 116

Query: 859 RVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTI--IFIRKAERSHSGKY 916
           + G  V L +   G P P + + +DGAEI ++ ++ + S+   +  + I +A    SG Y
Sbjct: 117 Q-GSQVRLQVRVTGIPTPVVKFYRDGAEI-QSSLDFQISQEGDLYSLLIAEAYPEDSGTY 174

Query: 917 DLQV--KVDKFVETASIDIQ 934
            +     V +   TA + +Q
Sbjct: 175 SVNATNSVGRATSTAELLVQ 194



 Score = 33.5 bits (75), Expect = 1.2
 Identities = 43/147 (29%), Positives = 59/147 (40%), Gaps = 10/147 (6%)

Query: 304   PKLEVKWYKNGQE-IRPSTKY-IFEHKGCQRILFINNCQMTDDSEYYVTA----GDEKCS 357
             PK  VKWY+ G+E I    KY I E KG    L I +    D + Y V A    G    +
Sbjct: 24583 PKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQLIIASVTDDDATVYQVRATNQGGSVSGT 24642

Query: 358   TELFVREP-PIMVTKQLED---TTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSR 413
               L V  P  I + K LE      A  GE V ++   S     V  ++ G+++I      
Sbjct: 24643 ASLEVEVPAKIHLPKTLEGMGAVHALRGEVVSIKIPFSGKPDPVITWQKGQDLIDNNGHY 24702

Query: 414   YRIRVEGKKHILIIEGATKADAAEYSV 440
               I       ++   G  + DA  Y V
Sbjct: 24703 QVIVTRSFTSLVFPNGVERKDAGFYVV 24729



 Score = 33.1 bits (74), Expect = 1.6
 Identities = 21/96 (21%), Positives = 41/96 (42%), Gaps = 3/96 (3%)

Query: 854 QTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQ---INIRNSETDTIIFIRKAER 910
           Q+ +   G          G P PE++W +DG  I  +    + I  S+    + I    +
Sbjct: 13  QSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKLTIPAVTK 72

Query: 911 SHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVK 946
           ++SG+Y L+        T++ ++ +     PP  V+
Sbjct: 73  ANSGRYSLKATNGSGQATSTAELLVKAETAPPNFVQ 108



 Score = 33.1 bits (74), Expect = 1.6
 Identities = 19/61 (31%), Positives = 27/61 (44%), Gaps = 1/61 (1%)

Query: 1071 ATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVN 1130
            AT  C     P  K+ W K+ + + +  +YRM S++ V  L I      D   Y C  V 
Sbjct: 2146 ATFECET-SEPFVKVKWYKDGMEVHEGDKYRMHSDRKVHFLSILTIDTSDAEDYSCVLVE 2204

Query: 1131 D 1131
            D
Sbjct: 2205 D 2205



 Score = 33.1 bits (74), Expect = 1.6
 Identities = 55/256 (21%), Positives = 103/256 (40%), Gaps = 21/256 (8%)

Query: 304   PKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTA----GDEKCSTE 359
             P  ++KWY+ G+E+  S KY     G    L +   +  D+  Y   A    G+ + S++
Sbjct: 24188 PLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVGEVETSSK 24247

Query: 360   LFVREPPIMVT--KQLEDTTAYCGERVELE-CEVSEDDANVKWFKNGEEIIPGPKSRYRI 416
             L ++  P         E      G  + L    +      + WF +G++++   ++    
Sbjct: 24248 LLLQATPQFHPGYPLKEKYYGAVGSTLRLHVMYIGRPVPAMTWF-HGQKLLQNSENITIE 24306

Query: 417   RVEGKKHILIIEGATKADAAEYSVMTTG--GQSSAKLSVDL--KPLKILTPLTDQTVNLG 472
               E   H+++     K  A +Y V  +   G   A L V++  KP K   P+  + + L 
Sbjct: 24307 NTEHYTHLVMKNVQRKTHAGKYKVQLSNVFGTVDAILDVEIQDKPDKPTGPIVIEAL-LK 24365

Query: 473   KEICLKCEISENIPGKWTKNGL----PVQESDRLKVVHKG-RIHKLVIANALTEDEGDY- 526
                 +  +   +  G W  N +      +E    ++V     +    I N LTE+ G Y 
Sbjct: 24366 NSAVISWKPPADDGGSWITNYVVEKCEAKEGAEWQLVSSAISVTTCRIVN-LTENAGYYF 24424

Query: 527   -VFAPDAYNVTLPAKV 541
              V A + + ++ P +V
Sbjct: 24425 RVSAQNTFGISDPLEV 24440



 Score = 32.3 bits (72), Expect = 2.7
 Identities = 28/116 (24%), Positives = 51/116 (43%), Gaps = 8/116 (6%)

Query: 130  KAGKHLQLKETFERHSRVYTFEMQIIKAKDNFAGNYRCEVTYKDKFDSCSFDLEVHESTG 189
            KAG+ +   +     S  Y   ++I++ +    G Y C+ + +    SC+  L V     
Sbjct: 4497 KAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTV----- 4551

Query: 190  TTPNIDIRSAFKRSGEGQEDAGELDFSGLLKRREVKQQEEEPQVDVWELLKNAKPS 245
            T P  + +          E   E+    +L++R    +EEEP+V+  +L K  KP+
Sbjct: 4552 TVPGGEKKVRKLLPERKPEPKEEVVLKSVLRKR---PEEEEPKVEPKKLEKVKKPA 4604



 Score = 32.3 bits (72), Expect = 2.7
 Identities = 16/45 (35%), Positives = 22/45 (48%), Gaps = 3/45 (6%)

Query: 843   PPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEI 887
             PP+  +P + K  Y   VGE V   +     P P +TW K G +I
Sbjct: 25317 PPEFTLPLYNKTAY---VGENVRFGVTITVHPEPHVTWYKSGQKI 25358



 Score = 32.0 bits (71), Expect = 3.5
 Identities = 27/97 (27%), Positives = 39/97 (40%), Gaps = 5/97 (5%)

Query: 274  KKSAAFAKILDPAYQVDKGGRVRFVVELAD-PKLEVKWYKNGQEIRPSTKYIFEHKGCQR 332
            K++A   K      +V  G   +F  E+   P +  +W+K G+EI  S K          
Sbjct: 4458 KRAAPVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYIS 4517

Query: 333  ILFINNCQMTDDSEYYVTAGDE----KCSTELFVREP 365
             L I   Q+ D  EY   A +E     C+  L V  P
Sbjct: 4518 SLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVTVP 4554



 Score = 31.6 bits (70), Expect = 4.5
 Identities = 26/88 (29%), Positives = 33/88 (37%), Gaps = 4/88 (4%)

Query: 1059 PLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSP 1118
            PL +   I G  A L C V       + W  N   I  D R +         L I +   
Sbjct: 2404 PLKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVKGTKQRLVINRTHA 2463

Query: 1119 YDGGTYCCKAVNDLGTVEIECKLEVKVI 1146
             D G Y  K +  +G VE  C L V+ I
Sbjct: 2464 SDEGPY--KLI--VGRVETNCNLSVEKI 2487



 Score = 31.2 bits (69), Expect = 5.9
 Identities = 15/66 (22%), Positives = 30/66 (45%), Gaps = 1/66 (1%)

Query: 287   YQVDKGGRVRFVVE-LADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDS 345
             Y +  G  ++  +  +  P+  + W K+G+ ++ +T+   E      +L I      D  
Sbjct: 17949 YSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFG 18008

Query: 346   EYYVTA 351
             +Y VTA
Sbjct: 18009 KYTVTA 18014



 Score = 30.8 bits (68), Expect = 7.7
 Identities = 22/58 (37%), Positives = 28/58 (48%), Gaps = 6/58 (10%)

Query: 1    MPEPTKKEENE--VPAPAPPPEEPSKEKEAGTTPAKDEEEVSPPSALP---PGLGSRA 53
            +PEPTK  E +  +P PAP P +P  E E  T      E    P A P   P +G +A
Sbjct: 4629 IPEPTKVPEIKPAIPLPAPEP-KPKPEAEVKTIKPPPVEPEPTPIAAPVTVPVVGKKA 4685


>gi|110349715 titin isoform N2-B [Homo sapiens]
          Length = 26926

 Score =  299 bits (766), Expect = 9e-81
 Identities = 218/756 (28%), Positives = 346/756 (45%), Gaps = 52/756 (6%)

Query: 297  FVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKC 356
            F  +L+  K  VKWY+NG+EI+   KY FE  G    L I +C++ D+ EY     D K 
Sbjct: 6345 FSCQLSREKANVKWYRNGREIKEGKKYKFEKDGSIHRLIIKDCRLDDECEYACGVEDRKS 6404

Query: 357  STELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRI 416
               LFV E P+ + +  +D     G  V    E+++D   V+W +N   ++ G K  +++
Sbjct: 6405 RARLFVEEIPVEIIRPPQDILEAPGADVVFLAELNKDKVEVQWLRNNMVVVQGDK--HQM 6462

Query: 417  RVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEIC 476
              EGK H L I      D  EY  +    ++ AKL +   P KI T   D  V++GK + 
Sbjct: 6463 MSEGKIHRLQICDIKPRDQGEYRFIAKDKEARAKLELAAAP-KIKTADQDLVVDVGKPLT 6521

Query: 477  LKC--EISENIPGKWTKNGLPV----------QESDRL---KVVHKGRIHKLVIANALTE 521
            +    +       +W K   P+          Q S R+   K   KGR +K+V+ N   +
Sbjct: 6522 MVVPYDAYPKAEAEWFKENEPLSTKTIDTTAEQTSFRILEAKKGDKGR-YKIVLQNKHGK 6580

Query: 522  DEGDYVFAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPK 581
             EG                + VID P  + +    + T T      L  E P++      
Sbjct: 6581 AEGFI-------------NLKVIDVPGPVRN---LEVTETFDGEVSLAWEEPLTDGGSKI 6624

Query: 582  AMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAG-----EAHAS 636
              +    + I   +  + T+        V  + +     ++ ++ +N  G     E    
Sbjct: 6625 IGYVVERRDIKRKTWVLATDRAESCEFTVTGLQKGGVEYLFRVSARNRVGTGEPVETDNP 6684

Query: 637  IKVKV-VDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLN 695
            ++ +   D P PP+  T+T+V      + WEPP YDGG+ I  Y IE + K S RW    
Sbjct: 6685 VEARSKYDVPGPPLNVTITDVNRFGVSLTWEPPEYDGGAEITNYVIELRDKTSIRWDTAM 6744

Query: 696  FDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFV----PLAVTSPPTLLTV 751
                ++ +     ++EG  Y  R+ A N IG+ KPS  + PFV    P+   SPP  LT 
Sbjct: 6745 TVRAEDLSATVTDVVEGQEYSFRVRAQNRIGVGKPSAAT-PFVKVADPIERPSPPVNLTS 6803

Query: 752  DSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDA 811
               T ++V ++W PP   G + + GY++E C EG ++WI  N  L+ +  + +TGL    
Sbjct: 6804 SDQTQSSVQLKWEPPLKDGGSPILGYIIERCEEGKDNWIRCNMKLVPELTYKVTGLEKGN 6863

Query: 812  KIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQ 871
            K   RV A N AG S+P     P+   +    P + +    K      V   + +++P  
Sbjct: 6864 KYLYRVSAENKAGVSDPSEILGPLTADDAFVEPTMDLSA-FKDGLEVIVPNPITILVPST 6922

Query: 872  GKPRPELTWKKDGAEIDK-NQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETAS 930
            G PRP  TW      ++  +++ ++       + I  +ERS  G Y L  K++  V+T S
Sbjct: 6923 GYPRPTATWCFGDKVLETGDRVKMKTLSAYAELVISPSERSDKGIYTL--KLENRVKTIS 6980

Query: 931  --IDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTV 988
              ID+ +I RP  P+ +K  D+  ++V LTW PP DDG + +TGY ++K +     W  V
Sbjct: 6981 GEIDVNVIARPSAPKELKFGDITKDSVHLTWEPPDDDGGSPLTGYVVEKREVSRKTWTKV 7040

Query: 989  IEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDA 1024
            ++       T+ +LV G EY F+V + N CG  E A
Sbjct: 7041 MDFVTDLEFTVPDLVQGKEYLFKVCARNKCGPGEPA 7076



 Score =  288 bits (737), Expect = 2e-77
 Identities = 165/503 (32%), Positives = 269/503 (53%), Gaps = 17/503 (3%)

Query: 536   TLPAKVHV---IDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIM 592
             TLP  V     I+PP+I LD  D    V + A   LRL + I G P P+  W + +  + 
Sbjct: 18594 TLPGSVVAQERIEPPEIELDA-DLRKVVVLRASATLRLFVTIKGRPEPEVKWEKAEGILT 18652

Query: 593   EGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPT 652
             +   R + E     + LVID   R DSG Y++ L+N +G   A + V+V+D P  PV  T
Sbjct: 18653 D---RAQIEVTSSFTMLVIDNVTRFDSGRYNLTLENNSGSKTAFVNVRVLDSPSAPVNLT 18709

Query: 653   VTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEG 712
             + EV  D   ++WEPP  DGG+ I  Y +E+++     +  +  + C +TTF  + + EG
Sbjct: 18710 IREVKKDSVTLSWEPPLIDGGAKITNYIVEKRETTRKAYATITNN-CTKTTFRIENLQEG 18768

Query: 713   VAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAA 772
              +Y  R+ A N  GI  P+  + P        PP  +T+  VT  T T++W  P+  G +
Sbjct: 18769 CSYYFRVLASNEYGIGLPAETTEPVKVSEPPLPPGRVTLVDVTRNTATIKWEKPESDGGS 18828

Query: 773   GLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYS 832
              + GYV+E   +G+E W    +  +   + TI+GL    +   RV AVN  G S+P+   
Sbjct: 18829 KITGYVVEMQTKGSEKWSTCTQ--VKTLEATISGLTAGEEYVFRVAAVNEKGRSDPRQLG 18886

Query: 833   QPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEI-DKNQ 891
              P++ ++I   P + +P H   T+  +  E + + +PF+G+P+  + W+KDG  + +  +
Sbjct: 18887 VPVIARDIEIKPSVELPFH---TFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTR 18943

Query: 892   INIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVW 951
             +N+ +S+T T + I++A +   G Y+L V       T  I I ++DRPGPP  ++I++V 
Sbjct: 18944 VNVSSSKTVTSLSIKEASKEDVGTYELCVSNSAGSITVPITIIVLDRPGPPGPIRIDEVS 19003

Query: 952   GENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFR 1011
              +++ ++W PP+ DG   I+ Y ++K +  S  W  V +   RTS  I  L  G+EY FR
Sbjct: 19004 CDSITISWNPPEYDGGCQISNYIVEKKETTSTTWHIVSQAVARTSIKIVRLTTGSEYQFR 19063

Query: 1012  VFSENMCGLSEDATMTKESAVIA 1034
             V +EN  G S   + ++ SAV+A
Sbjct: 19064 VCAENRYGKS---SYSESSAVVA 19083



 Score =  276 bits (707), Expect = 6e-74
 Identities = 176/570 (30%), Positives = 286/570 (50%), Gaps = 35/570 (6%)

Query: 463   PLTDQTVNLGKEICLKCEISENIPGKWTKNGLPVQ------ESDRLKVVHKGRIHKLVIA 516
             P+ D    +   I  KC++S    G+WT    P        E ++L   H+       I 
Sbjct: 16364 PIYDGGCEIQGYIVEKCDVSV---GEWTMCTPPTGINKTNIEVEKLLEKHEYNFRICAIN 16420

Query: 517   NALTEDEGDYVFAPDAYNVTLPAKVHV---IDPPKIILDGLDADNTVTVIAGNKLRLEIP 573
              A   +  D           +P  + V   ++ P I LD L+    + + AG  LRL +P
Sbjct: 16421 KAGVGEHAD-----------VPGPIIVEEKLEAPDIDLD-LELRKIINIRAGGSLRLFVP 16468

Query: 574   ISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEA 633
             I G P P+  W + D  I + +    T S+   ++LV+D   R DSG Y + L+N +G  
Sbjct: 16469 IKGRPTPEVKWGKVDGEIRDAAIIDVTSSF---TSLVLDNVNRYDSGKYTLTLENSSGTK 16525

Query: 634   HASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMR 693
              A + V+V+D P PPV   VTE+  D   + WEPP  DGGS I  Y +E+++     +  
Sbjct: 16526 SAFVTVRVLDTPSPPVNLKVTEITKDSVSITWEPPLLDGGSKIKNYIVEKREATRKSYAA 16585

Query: 694   LNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDS 753
             +  + C + +++  ++ EG +Y  R+ A N  GI  P+  + P     V  PP  +TVD 
Sbjct: 16586 VVTN-CHKNSWKIDQLQEGCSYYFRVTAENEYGIGLPAQTADPIKVAEVPQPPGKITVDD 16644

Query: 754   VTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKI 813
             VT  +V++ W  P+H G + +  Y++E   + +E W    +  +   +  IT L    + 
Sbjct: 16645 VTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKHSEKWSECAR--VKSLQAVITNLTQGEEY 16702

Query: 814   FVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGK 873
               RV AVN  G S+P+  + PI+ K+++  P +   +    +Y  +VG+ + + +P  G+
Sbjct: 16703 LFRVVAVNEKGRSDPRSLAVPIVAKDLVIEPDV---KPAFSSYSVQVGQDLKIEVPISGR 16759

Query: 874   PRPELTWKKDGAEIDK-NQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASID 932
             P+P +TW KDG  + +  +IN+ +S   T + I++  +   G+Y + V      +TASI+
Sbjct: 16760 PKPTITWTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDGGQYGITVANVVGQKTASIE 16819

Query: 933   IQIIDRPGPPQ-IVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEH 991
             I  +D+P PP+  VK +DV  E++ L+W PP   G   IT Y +QK D  +  W  V   
Sbjct: 16820 IVTLDKPDPPKGPVKFDDVSAESITLSWNPPLYTGGCQITNYIVQKRDTTTTVWDVVSAT 16879

Query: 992   YHRTSATITELVIGNEYYFRVFSENMCGLS 1021
               RT+  +T+L  G EY FR+F+EN  G S
Sbjct: 16880 VARTTLKVTKLKTGTEYQFRIFAENRYGQS 16909



 Score =  272 bits (695), Expect = 2e-72
 Identities = 159/562 (28%), Positives = 280/562 (49%), Gaps = 19/562 (3%)

Query: 544   IDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESY 603
             ++ P++ LD  +    + V AG   R+ IP  G P P+  WSR +    E + +++ E  
Sbjct: 17522 LEAPELDLDS-ELRKGIVVRAGGSARIHIPFKGRPTPEITWSREEG---EFTDKVQIEKG 17577

Query: 604   PDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIM 663
              + + L ID  +R+D+G Y + L+N +G   A + VKV+D P PP    V EV  D   +
Sbjct: 17578 VNYTQLSIDNCDRNDAGKYILKLENSSGSKSAFVTVKVLDTPGPPQNLAVKEVRKDSAFL 17637

Query: 664   NWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVN 723
              WEPP  DGG+ +  Y I++++     +  ++   C +T+F+ + + EG  Y  R+ A N
Sbjct: 17638 VWEPPIIDGGAKVKNYVIDKRESTRKAYANVS-SKCSKTSFKVENLTEGAIYYFRVMAEN 17696

Query: 724   AIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCF 783
               G+  P             SPP  +T+  V+ T+ ++ W  P+H G + + GYV+E   
Sbjct: 17697 EFGVGVPVETVDAVKAAEPPSPPGKVTLTDVSQTSASLMWEKPEHDGGSRVLGYVVEMQP 17756

Query: 784   EGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEP 843
             +GTE W +  +  +      +TGL +  +   RVKA N  G S+P+    P++ K++   
Sbjct: 17757 KGTEKWSIVAESKV--CNAVVTGLSSGQEYQFRVKAYNEKGKSDPRVLGVPVIAKDLTIQ 17814

Query: 844   PKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDK-NQINIRNSETDTI 902
             P +++P +   TY  + GE + + IP  G+PRP ++W KDG  + +  ++N+  + T T+
Sbjct: 17815 PSLKLPFN---TYSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTV 17871

Query: 903   IFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPP-QIVKIEDVWGENVALTWTP 961
             + I++  +   GKY +         T ++ + ++++PGPP   V+ ++V  + V ++W P
Sbjct: 17872 LHIKEGNKDDFGKYTVTATNSAGTATENLSVIVLEKPGPPVGPVRFDEVSADFVVISWEP 17931

Query: 962   PKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLS 1021
             P   G   I+ Y ++K D  +  W  V     RT+  IT+L  G EY FR+F+EN  G S
Sbjct: 17932 PAYTGGCQISNYIVEKRDTTTTTWHMVSATVARTTIKITKLKTGTEYQFRIFAENRYGKS 17991

Query: 1022  EDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNAT--LNCSVRG 1079
               A +  ++ ++      +K P      F  +    Q LV  +       T  +   +  
Sbjct: 17992 --APLDSKAVIVQYP---FKEPGPPGTPFVTSISKDQMLVQWHEPVNDGGTKIIGYHLEQ 18046

Query: 1080  NPKPKITWMKNKVAIVDDPRYR 1101
               K  I W+K     + D +++
Sbjct: 18047 KEKNSILWVKLNKTPIQDTKFK 18068



 Score =  258 bits (658), Expect = 3e-68
 Identities = 148/478 (30%), Positives = 252/478 (52%), Gaps = 12/478 (2%)

Query: 546   PPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPD 605
             PP+I LD  D    VT+ A   LRL +PI G P P+  W+R     ++ +    T SY  
Sbjct: 15360 PPEIELDA-DLRKVVTIRACCTLRLFVPIKGRPAPEVKWARDHGESLDKASIESTSSY-- 15416

Query: 606   SSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNW 665
              + L++    R DSG Y + ++N +G   A + V+V+D P PP    V EV      + W
Sbjct: 15417 -TLLIVGNVNRFDSGKYILTVENSSGSKSAFVNVRVLDTPGPPQDLKVKEVTKTSVTLTW 15475

Query: 666   EPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAI 725
             +PP  DGGS I  Y +E+++     +  +  + C +T+++  ++ EG +Y  R+ A N  
Sbjct: 15476 DPPLLDGGSKIKNYIVEKRESTRKAYSTVATN-CHKTSWKVDQLQEGCSYYFRVLAENEY 15534

Query: 726   GISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEG 785
             GI  P+  +          PP  +T+  VT  +V++ W  P+H G + + GY++E   +G
Sbjct: 15535 GIGLPAETAESVKASERPLPPGKITLMDVTRNSVSLSWEKPEHDGGSRILGYIVEMQTKG 15594

Query: 786   TEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPK 845
             ++ W  A    +  T+ TITGL    +   RV A N  G S+P+  S P++ K+++ PP 
Sbjct: 15595 SDKW--ATCATVKVTEATITGLIQGEEYSFRVSAQNEKGISDPRQLSVPVIAKDLVIPPA 15652

Query: 846   IRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDK-NQINIRNSETDTIIF 904
              ++   L  T+    GE + + +PF G+P P +TW KD   + +  ++N  ++E ++++ 
Sbjct: 15653 FKL---LFNTFTVLAGEDLKVDVPFIGRPTPAVTWHKDNVPLKQTTRVNAESTENNSLLT 15709

Query: 905   IRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQ-IVKIEDVWGENVALTWTPPK 963
             I+ A R   G Y +++         ++++ ++D+PGPP   VK+++V  +++ L+W PPK
Sbjct: 15710 IKDACREDVGHYVVKLTNSAGEAIETLNVIVLDKPGPPTGPVKMDEVTADSITLSWGPPK 15769

Query: 964   DDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLS 1021
              DG ++I  Y ++K D  +  W  V     RT+     L  G EY FR+ +EN  G S
Sbjct: 15770 YDGGSSINNYIVEKRDTSTTTWQIVSATVARTTIKACRLKTGCEYQFRIAAENRYGKS 15827



 Score =  255 bits (651), Expect = 2e-67
 Identities = 157/482 (32%), Positives = 251/482 (52%), Gaps = 13/482 (2%)

Query: 547   PKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDS 606
             P + LD    D  V V AG  +R+   +SG+PPP   W+  ++ + + +     E+   S
Sbjct: 10025 PDLQLDASVRDRIV-VHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEA---TIETTAIS 10080

Query: 607   STLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTE-VGDDWCIMNW 665
             S++VI   +R   GVY +  KNEAGE   +I V V+D P P   P +   + ++ C + W
Sbjct: 10081 SSMVIKNCQRSHQGVYSLLAKNEAGERKKTIIVDVLDVPGPVGTPFLAHNLTNESCKLTW 10140

Query: 666   EPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAI 725
               P  DGGSPI  Y IE+++     W  + + + ++     + +I+G AY  RI A N+I
Sbjct: 10141 FSPEDDGGSPITNYVIEKRESDRRAWTPVTYTVTRQNA-TVQGLIQGKAYFFRIAAENSI 10199

Query: 726   GISKPSMPSRPFV---PLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYC 782
             G+      S   V   P+ V   P  L V  VT  TVT+ W PP + G + +  YVLE  
Sbjct: 10200 GMGPFVETSEALVIREPITVPERPEDLEVKEVTKNTVTLTWNPPKYDGGSEIINYVLESR 10259

Query: 783   FEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIE 842
               GTE +     D +   K+T+ GL        RV AVN  G  +P + ++PI  K+ + 
Sbjct: 10260 LIGTEKFHKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGKPSFCTKPITCKDELA 10319

Query: 843   PPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEI-DKNQINIRNSETDT 901
             PP + +    K T   RVGEA  L   + GKP+P+++W KD A++ + ++ +I+ +    
Sbjct: 10320 PPTLHLDFRDKLTI--RVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATL 10377

Query: 902   IIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPP-QIVKIEDVWGENVALTWT 960
              +   KA+RS SGKY + V+           + ++DRPGPP   V  ++V  + + ++W 
Sbjct: 10378 ALEKIKAKRSDSGKYCVVVENSTGSRKGFCQVNVVDRPGPPVGPVSFDEVTKDYMVISWK 10437

Query: 961   PPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGL 1020
             PP DDG + IT Y I+K +     W  V     +T+  +++L+ G +Y FR+ +EN+ G+
Sbjct: 10438 PPLDDGGSKITNYIIEKKEVGKDVWMPVTSASAKTTCKVSKLLEGKDYIFRIHAENLYGI 10497

Query: 1021  SE 1022
             S+
Sbjct: 10498 SD 10499



 Score =  255 bits (651), Expect = 2e-67
 Identities = 143/470 (30%), Positives = 242/470 (51%), Gaps = 16/470 (3%)

Query: 559   TVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSS----TLVIDIA 614
             T+ V AG    + +P  G P P  +WS+ D  +       RT +Y D++    +L I+ A
Sbjct: 19698 TLIVKAGASFTMTVPFRGRPVPNVLWSKPDTDL-------RTRAYVDTTDSRTSLTIENA 19750

Query: 615   ERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGS 674
              R+DSG Y + ++N    A  ++ VKV+D P PP   TV +V  +  +++W+ P  DGG+
Sbjct: 19751 NRNDSGKYTLTIQNVLSAASLTLVVKVLDTPGPPTNITVQDVTKESAVLSWDVPENDGGA 19810

Query: 675   PILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPS 734
             P+  Y IE+++     W+ +  + C   +++   + EG  Y  R+   N  G+  P+   
Sbjct: 19811 PVKNYHIEKREASKKAWVSVT-NNCNRLSYKVTNLQEGAIYYFRVSGENEFGVGIPAETK 19869

Query: 735   RPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANK 794
                      SPP  L V S++  +V++ W  P+H G + +  YV+E   +G ++W+    
Sbjct: 19870 EGVKITEKPSPPEKLGVTSISKDSVSLTWLKPEHDGGSRIVHYVVEALEKGQKNWVKC-- 19927

Query: 795   DLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQ 854
              +   T   ++GL  +++ F RV A N AG S+P+    P+L+KE +EPP+I +      
Sbjct: 19928 AVAKSTHHVVSGLRENSEYFFRVFAENQAGLSDPRELLLPVLIKEQLEPPEIDMKNFPSH 19987

Query: 855   TYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKN-QINIRNSETDTIIFIRKAERSHS 913
             T   R G  + + IP  GKP P++T  +DG  +    + N   +  +  I ++++  + +
Sbjct: 19988 TVYVRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADA 20047

Query: 914   GKYDLQVKVDKFVETASIDIQIIDRPGPPQ-IVKIEDVWGENVALTWTPPKDDGNAAITG 972
             G+Y++          A I+I ++DRPGPP   V I D+  E+V L W PPK DG + +T 
Sbjct: 20048 GRYEITAANSSGTTKAFINIVVLDRPGPPTGPVVISDITEESVTLKWEPPKYDGGSQVTN 20107

Query: 973   YTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSE 1022
             Y + K +  +  W  V     RT   + +L  G EY FR+ +EN  G+S+
Sbjct: 20108 YILLKRETSTAVWTEVSATVARTMMKVMKLTTGEEYQFRIKAENRFGISD 20157



 Score =  252 bits (644), Expect = 1e-66
 Identities = 152/470 (32%), Positives = 240/470 (51%), Gaps = 10/470 (2%)

Query: 555   DADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIA 614
             D   TVT+ AG  LRL + +SG PPP   WS+    +   +    TESY   S L++D  
Sbjct: 22954 DLKKTVTIRAGASLRLMVSVSGRPPPVITWSKQGIDLASRAIIDTTESY---SLLIVDKV 23010

Query: 615   ERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGS 674
              R D+G Y I  +N++G+  A++ VKV D P P  +  V EV  D   + WE P  DGG+
Sbjct: 23011 NRYDAGKYTIEAENQSGKKSATVLVKVYDTPGPCPSVKVKEVSRDSVTITWEIPTIDGGA 23070

Query: 675   PILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPS 734
             P+  Y +E K++ + R  +     C +T +    ++EG  Y  R+   N  GI +P   S
Sbjct: 23071 PVNNYIVE-KREAAMRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYGIGEPCETS 23129

Query: 735   RPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDW--IVA 792
                +   V   P  L V  VT +TVT+ W  P + G + L GYVLE C  GTE W  +V 
Sbjct: 23130 DAVLVSEVPLVPAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGTERWMKVVT 23189

Query: 793   NKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHL 852
              K  +   + T+T L    +   R++A N  G SEP+     + V+++   P I +    
Sbjct: 23190 LKPTV--LEHTVTSLNEGEQYLFRIRAQNEKGVSEPRETVTAVTVQDLRVLPTIDLSTMP 23247

Query: 853   KQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEI-DKNQINIRNSETDTIIFIRKAERS 911
             ++T     G  V LVIP  G+P P  +W   G+++ +  ++ +        + IR+    
Sbjct: 23248 QKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAKLTIRETTIR 23307

Query: 912   HSGKYDLQVKVDKFVETASIDIQIIDRPGPPQ-IVKIEDVWGENVALTWTPPKDDGNAAI 970
              +G+Y L++K      + +I + I+D+PGPP   +KI+++   ++ ++W PP+ DG A +
Sbjct: 23308 DTGEYTLELKNVTGTTSETIKVIILDKPGPPTGPIKIDEIDATSITISWEPPELDGGAPL 23367

Query: 971   TGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGL 1020
             +GY +++ D     W  V E   R++   T L  GNEY FRV + N  G+
Sbjct: 23368 SGYVVEQRDAHRPGWLPVSESVTRSTFKFTRLTEGNEYVFRVAATNRFGI 23417



 Score =  249 bits (636), Expect = 1e-65
 Identities = 151/508 (29%), Positives = 245/508 (48%), Gaps = 22/508 (4%)

Query: 533  YNVTLPAKVHVIDPPKIILDGLDADNT--------------VTVIAGNKLRLEIPISGEP 578
            Y V+   K  V DP +I L  L AD+               + VI  N + + +P +G P
Sbjct: 6867 YRVSAENKAGVSDPSEI-LGPLTADDAFVEPTMDLSAFKDGLEVIVPNPITILVPSTGYP 6925

Query: 579  PPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIK 638
             P A W  GDK ++E   R++ ++    + LVI  +ER D G+Y + L+N        I 
Sbjct: 6926 RPTATWCFGDK-VLETGDRVKMKTLSAYAELVISPSERSDKGIYTLKLENRVKTISGEID 6984

Query: 639  VKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDL 698
            V V+  P  P      ++  D   + WEPP  DGGSP+ GY +E+++     W ++  D 
Sbjct: 6985 VNVIARPSAPKELKFGDITKDSVHLTWEPPDDDGGSPLTGYVVEKREVSRKTWTKV-MDF 7043

Query: 699  CKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPF---VPLAVTSPPTLLTVDSVT 755
              +  F    +++G  Y  ++ A N  G  +P+    P     P  V  PP  +     T
Sbjct: 7044 VTDLEFTVPDLVQGKEYLFKVCARNKCGPGEPAYVDEPVNMSTPATVPDPPENVKWRDRT 7103

Query: 756  DTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFV 815
              ++ + W PP + G + + GY++E C  G++ W+   +  + +TK  +TGL        
Sbjct: 7104 ANSIFLTWDPPKNDGGSRIKGYIVERCPRGSDKWVACGEP-VAETKMEVTGLEEGKWYAY 7162

Query: 816  RVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPR 875
            RVKA+N  GAS+P   ++ I   +  E P+I +   L      + G  + L     GKP 
Sbjct: 7163 RVKALNRQGASKPSRPTEEIQAVDTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPE 7222

Query: 876  PELTWKKDGAEIDKN-QINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQ 934
            P++TW K    + ++ +I I N    + + I  ++RS +G Y ++        TA +++ 
Sbjct: 7223 PKITWTKADMILKQDKRITIENVPKKSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVN 7282

Query: 935  IIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHR 994
            ++D+PGPP    I DV  E+  LTW PP+DDG + IT Y +++    S  W  +      
Sbjct: 7283 VLDKPGPPAAFDITDVTNESCLLTWNPPRDDGGSKITNYVVERRATDSEVWHKLSSTVKD 7342

Query: 995  TSATITELVIGNEYYFRVFSENMCGLSE 1022
            T+   T+L+   EY FRV +ENM G+ E
Sbjct: 7343 TNFKATKLIPNKEYIFRVAAENMYGVGE 7370



 Score =  247 bits (631), Expect = 4e-65
 Identities = 170/584 (29%), Positives = 278/584 (47%), Gaps = 33/584 (5%)

Query: 461   LTPLTDQTVNL--GKEICLKCEISENIP--GKWTKNGLPVQESDRLKVVHKGRIHKLVIA 516
             L+ +  +T+++  G+ + L   I+   P    W   G  ++ES+R+ V    ++ KL I 
Sbjct: 23243 LSTMPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLRESERVTVETHTKVAKLTIR 23302

Query: 517   NALTEDEGDYVFAPDAYNVTLPA----KVHVIDPP-----KIILDGLDADNTVTVIAGNK 567
                  D G+Y    +  NVT       KV ++D P      I +D +DA +        +
Sbjct: 23303 ETTIRDTGEYTL--ELKNVTGTTSETIKVIILDKPGPPTGPIKIDEIDATSITISWEPPE 23360

Query: 568   LRLEIPISG-----EPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVY 622
             L    P+SG         +  W    +++   + +    +  +     +    R   G Y
Sbjct: 23361 LDGGAPLSGYVVEQRDAHRPGWLPVSESVTRSTFKFTRLTEGNEYVFRVAATNRFGIGSY 23420

Query: 623   HINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIE 682
                L++E  E  +SI++     P PP    + +V  D   + W PP  DGGS + GY +E
Sbjct: 23421 ---LQSEVIECRSSIRI-----PGPPETLQIFDVSRDGMTLTWYPPEDDGGSQVTGYIVE 23472

Query: 683   RKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAV 742
             RK+ ++ RW+R+N      T +    + EG+ YE R+ A+NA G  KPS PS+P V +  
Sbjct: 23473 RKEVRADRWVRVNKVPVTMTRYRSTGLTEGLEYEHRVTAINARGSGKPSRPSKPIVAMDP 23532

Query: 743   TSPPTLLTVDSVTDTT---VTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDK 799
              +PP       VTDTT   V++ W  P+  G + + GY++E       +W   N      
Sbjct: 23533 IAPPGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTKCNTTPTKI 23592

Query: 800   TKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRR 859
              ++T+T LP  A+   RV A NA G  EP      + V E++E P   +    ++    R
Sbjct: 23593 REYTLTHLPQGAEYRFRVLACNAGGPGEPAEVPGTVKVTEMLEYPDYELDERYQEGIFVR 23652

Query: 860   VGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQ 919
              G  + L IP +GKP P   W K+G +I K  + I  SET T + I++A+R  SG YDL 
Sbjct: 23653 QGGVIRLTIPIKGKPFPICKWTKEGQDISKRAM-IATSETHTELVIKEADRGDSGTYDLV 23711

Query: 920   VKVDKFVETASIDIQIIDRPGPPQ-IVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKA 978
             ++     +   I +++I  P  P+  ++ +D+   +V ++W PP DDG A I GY +++ 
Sbjct: 23712 LENKCGKKAVYIKVRVIGSPNSPEGPLEYDDIQVRSVRVSWRPPADDGGADILGYILERR 23771

Query: 979   DKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSE 1022
             +     W+T+      TS  +  L    EY+FRV +EN  G+S+
Sbjct: 23772 EVPKAAWYTIDSRVRGTSLVVKGLKENVEYHFRVSAENQFGISK 23815



 Score =  245 bits (626), Expect = 2e-64
 Identities = 153/493 (31%), Positives = 238/493 (48%), Gaps = 17/493 (3%)

Query: 543   VIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRG--DKAIMEGSGRIRT 600
             +++PP+I LD       V V AG  +RL   + G P PK  W +   D  + +G    + 
Sbjct: 12103 ILEPPEIDLDA-SMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVVRKG----QV 12157

Query: 601   ESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDW 660
             +     + LVI  + RDDSG Y + L N AGE    + V+V+D P P     V++V    
Sbjct: 12158 DLVDTMAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFVNVRVLDTPGPVSDLKVSDVTKTS 12217

Query: 661   CIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIF 720
             C ++W PP  DGGS +  Y +E+++     W  +  ++ K+T+F    ++ G  Y  R+ 
Sbjct: 12218 CHVSWAPPENDGGSQVTHYIVEKREADRKTWSTVTPEV-KKTSFHVTNLVPGNEYYFRVT 12276

Query: 721   AVNAIGISKPSMPSRPFV---PLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGY 777
             AVN  G   P+   +P +   PL+   PP  L V  +T  + T+ W PP   G A +DGY
Sbjct: 12277 AVNEYGPGVPTDVPKPVLASDPLSEPDPPRKLEVTEMTKNSATLAWLPPLRDGGAKIDGY 12336

Query: 778   VLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILV 837
             +  Y  E           ++      +TGL    K   RV A NA G S P+        
Sbjct: 12337 ITSYREEEQPADRWTEYSVVKDLSLVVTGLKEGKKYKFRVAARNAVGVSLPREAEGVYEA 12396

Query: 838   KEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAE-IDKNQINIRN 896
             KE + PPKI +P  +      + G+ + +     GKP P   WKK   E +  + + +  
Sbjct: 12397 KEQLLPPKILMPEQI----TIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHK 12452

Query: 897   SETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQ-IVKIEDVWGENV 955
             +++ +I+ I+   R  SG Y L  +     +T  I + ++D PGPPQ    I D+  +  
Sbjct: 12453 ADSSSILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPGPPQPPFDISDIDADAC 12512

Query: 956   ALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSE 1015
             +L+W  P +DG + IT Y ++K D    +W T +    +TS  + +L+ G EY FRV +E
Sbjct: 12513 SLSWHIPLEDGGSNITNYIVEKCDVSRGDWVTALASVTKTSCRVGKLIPGQEYIFRVRAE 12572

Query: 1016  NMCGLSEDATMTK 1028
             N  G+SE  T  K
Sbjct: 12573 NRFGISEPLTSPK 12585



 Score =  243 bits (621), Expect = 6e-64
 Identities = 152/515 (29%), Positives = 259/515 (50%), Gaps = 25/515 (4%)

Query: 543   VIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTES 602
             ++ PP+  LD  D   T+ + AG  +RL +P+ G PPPK  WS+ +  + +  G +  +S
Sbjct: 13190 ILIPPEGELDA-DLRKTLILRAGVTMRLYVPVKGRPPPKITWSKPNVNLRDRIG-LDIKS 13247

Query: 603   YPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCI 662
                 + L  +   + D+G Y + L+N  G+   +I VKV+D P PPV  TV E+  D   
Sbjct: 13248 TDFDTFLRCENVNKYDAGKYILTLENSCGKKEYTIVVKVLDTPGPPVNVTVKEISKDSAY 13307

Query: 663   MNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAV 722
             + WEPP  DGGSPI+ Y ++++  +   W  +  + C +T+F    + EG +Y  R+FA 
Sbjct: 13308 VTWEPPIIDGGSPIINYVVQKRDAERKSWSTVTTE-CSKTSFRVANLEEGKSYFFRVFAE 13366

Query: 723   NAIGISKPSMPSRPFVPLAVTSPPTL-LTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEY 781
             N  GI  P   +R  V  + T  P + L V SV+ ++ ++ W+ P   G + + GYV+++
Sbjct: 13367 NEYGIGDPG-ETRDAVKASQTPGPVVDLKVRSVSKSSCSIGWKKPHSDGGSRIIGYVVDF 13425

Query: 782   CFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEII 841
               E  + W    K L    +++   L    +   RV A N  G   P   +  ++ ++ +
Sbjct: 13426 LTEENK-WQRVMKSL--SLQYSAKDLTEGKEYTFRVSAENENGEGTPSEIT--VVARDDV 13480

Query: 842   EPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKK-DGAEIDKNQINIRNSETD 900
               P + +       Y+ +      L IP +GKP P ++WKK +       ++++ +S  +
Sbjct: 13481 VAPDLDLKGLPDLCYLAKENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVESSAVN 13540

Query: 901   TIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPG-PPQIVKIEDVWGENVALTW 959
             T + +   ++S +GKY + +K     +  +I I+++ +PG P   +K ++V  E + L W
Sbjct: 13541 TTLIVYDCQKSDAGKYTITLKNVAGTKEGTISIKVVGKPGIPTGPIKFDEVTAEAMTLKW 13600

Query: 960   TPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCG 1019
              PPKDDG + IT Y ++K D  + +W T      +T+  +T L  G EY FRV +EN  G
Sbjct: 13601 APPKDDGGSEITNYILEKRDSVNNKWVTCASAVQKTTFRVTRLHEGMEYTFRVSAENKYG 13660

Query: 1020  LSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAP 1054
             + E     K   ++AR            FD  +AP
Sbjct: 13661 VGEG---LKSEPIVAR----------HPFDVPDAP 13682



 Score =  243 bits (620), Expect = 8e-64
 Identities = 202/709 (28%), Positives = 322/709 (45%), Gaps = 69/709 (9%)

Query: 357   STELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKW----FKNGEEIIP---- 408
             S  L +REP I V ++ ED        +E++ EV+++   + W    +  G EII     
Sbjct: 10208 SEALVIREP-ITVPERPED--------LEVK-EVTKNTVTLTWNPPKYDGGSEIINYVLE 10257

Query: 409   ----GPKSRYRIRVEGK-KHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTP 463
                 G +  +++  +        ++G  + D  EY V         K S   KP+     
Sbjct: 10258 SRLIGTEKFHKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQGKPSFCTKPITCKDE 10317

Query: 464   LTDQTVNLGKEICLKCEISE------NIPGK------WTKNGLPVQESDRLKVVHKGRIH 511
             L   T++L     L   + E         GK      W K+   V E DR  +       
Sbjct: 10318 LAPPTLHLDFRDKLTIRVGEAFALTGRYSGKPKPKVSWFKDEADVLEDDRTHIKTTPATL 10377

Query: 512   KLVIANALTEDEGDYVFAPDAYNVTLPAK----VHVIDPPKIILDGLDADNTVTVIAGNK 567
              L    A   D G Y    +  N T   K    V+V+D P   +  +  D          
Sbjct: 10378 ALEKIKAKRSDSGKYCVVVE--NSTGSRKGFCQVNVVDRPGPPVGPVSFDEVT------- 10428

Query: 568   LRLEIPISGEPPPKAMWSRGDKAIMEGSGRIR------TESYPDSSTLVIDIAERDDSGV 621
              +  + IS +PP     S+    I+E     +      T +   ++  V  + E  D  +
Sbjct: 10429 -KDYMVISWKPPLDDGGSKITNYIIEKKEVGKDVWMPVTSASAKTTCKVSKLLEGKDY-I 10486

Query: 622   YHINLKNEAG--EAHASIKVKVVD---FPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPI 676
             + I+ +N  G  +   S  +K  D    PD P  P VTEV  D  ++ W  P +DGG PI
Sbjct: 10487 FRIHAENLYGISDPLVSDSMKAKDRFRVPDAPDQPIVTEVTKDSALVTWNKP-HDGGKPI 10545

Query: 677   LGYFIERKKKQSSRWMRLNFD-LCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSR 735
               Y +E+++  S RW R+  D +   T F    ++EG  YE R+ A N IGI  PS PS+
Sbjct: 10546 TNYILEKRETMSKRWARVTKDPIHPYTKFRVPDLLEGCQYEFRVSAENEIGIGDPSPPSK 10605

Query: 736   PFV---PLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVA 792
             P     P+A  SPP        T  +V + W+PP H G + + GY++EY   G E+W  A
Sbjct: 10606 PVFAKDPIAKPSPPVNPEAIDTTCNSVDLTWQPPRHDGGSKILGYIVEYQKVGDEEWRRA 10665

Query: 793   NK--DLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPR 850
             N   +   +TK+ +TGL        RV AVNAAG S+P +  +P+LVK+ +EPP++ +  
Sbjct: 10666 NHTPESCPETKYKVTGLRDGQTYKFRVLAVNAAGESDPAHVPEPVLVKDRLEPPELILDA 10725

Query: 851   HLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAER 910
             ++ +    +VG+ + L    +G P P++TWKK+  +    +  I  +   + + IR A  
Sbjct: 10726 NMAREQHIKVGDTLRLSAIIKGVPFPKVTWKKEDRDAP-TKARIDVTPVGSKLEIRNAAH 10784

Query: 911   SHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAI 970
                G Y L V+     +T S+ + ++D+PGPP+ +++ ++  ++  LTW  P DDG + I
Sbjct: 10785 EDGGIYSLTVENPAGSKTVSVKVLVLDKPGPPRDLEVSEIRKDSCYLTWKEPLDDGGSVI 10844

Query: 971   TGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCG 1019
             T Y +++ D  S +W  +     + S     L  GN+Y FRV +EN  G
Sbjct: 10845 TNYVVERRDVASAQWSPLSATSKKKSHFAKHLNEGNQYLFRVAAENQYG 10893



 Score =  243 bits (620), Expect = 8e-64
 Identities = 166/560 (29%), Positives = 272/560 (48%), Gaps = 26/560 (4%)

Query: 489   WTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAKVH--VIDP 546
             W K+G+ ++E  R +++       L + + +  D G YV        T    V+  V+D 
Sbjct: 19326 WAKDGIEIEERARTEIISTDNHTLLTVKDCIRRDTGQYVLTLKNVAGTRSVAVNCKVLDK 19385

Query: 547   P-----KIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTE 601
             P      + ++GL A+         +      I      K   S     I EG  ++   
Sbjct: 19386 PGPPAGPLEINGLTAEKCSLSWGRPQEDGGADIDYYIVEKRETSHLAWTICEGELQM--- 19442

Query: 602   SYPDSSTLVIDIAERDDSGVYHINLKNE--AGEAHASIKVKVVD---FPDPPVAPTVTEV 656
                 +S  V  + + ++  ++ +   N+   GE   S+ +K +D    P PP +  +T V
Sbjct: 19443 ----TSCKVTKLLKGNEY-IFRVTGVNKYGVGEPLESVAIKALDPFTVPSPPTSLEITSV 19497

Query: 657   GDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYE 716
               +   + W  P  DGGS I GY IER++K S RW+R+N     +   +   + EG  YE
Sbjct: 19498 TKESMTLCWSRPESDGGSEISGYIIERREKNSLRWVRVNKKPVYDLRVKSTGLREGCEYE 19557

Query: 717   VRIFAVNAIGISKPSMPS---RPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAG 773
              R++A NA G+S PS  S   R   P+ + SPP+   +     TT+T+ W  P   G A 
Sbjct: 19558 YRVYAENAAGLSLPSETSPLIRAEDPVFLPSPPSKPKIVDSGKTTITIAWVKPLFDGGAP 19617

Query: 774   LDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQ 833
             + GY +EY      DW  + + L   T++TI+GL T A+   RVK+VN  GAS+P   S 
Sbjct: 19618 ITGYTVEYKKSDDTDWKTSIQSLRG-TEYTISGLTTGAEYVFRVKSVNKVGASDPSDSSD 19676

Query: 834   PILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQIN 893
             P + KE  E P   I   +++T I + G +  + +PF+G+P P + W K   ++ + +  
Sbjct: 19677 PQIAKEREEEPLFDIDSEMRKTLIVKAGASFTMTVPFRGRPVPNVLWSKPDTDL-RTRAY 19735

Query: 894   IRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGE 953
             +  +++ T + I  A R+ SGKY L ++      + ++ ++++D PGPP  + ++DV  E
Sbjct: 19736 VDTTDSRTSLTIENANRNDSGKYTLTIQNVLSAASLTLVVKVLDTPGPPTNITVQDVTKE 19795

Query: 954   NVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVF 1013
             +  L+W  P++DG A +  Y I+K +     W +V  + +R S  +T L  G  YYFRV 
Sbjct: 19796 SAVLSWDVPENDGGAPVKNYHIEKREASKKAWVSVTNNCNRLSYKVTNLQEGAIYYFRVS 19855

Query: 1014  SENMCGLSEDATMTKESAVI 1033
              EN  G+   A  TKE   I
Sbjct: 19856 GENEFGVGIPAE-TKEGVKI 19874



 Score =  241 bits (614), Expect = 4e-63
 Identities = 135/381 (35%), Positives = 198/381 (51%), Gaps = 3/381 (0%)

Query: 645   PDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTF 704
             P PP  P VT V  D   ++W  P  DGGSPILGY +ERK++    W  ++  L     F
Sbjct: 14762 PGPPGTPQVTAVTKDSMTISWHEPLSDGGSPILGYHVERKERNGILWQTVSKALVPGNIF 14821

Query: 705   EPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWR 764
             +   + +G+AYE R+ A N  G SKPS PS P + L    PP      ++T  TVT++W 
Sbjct: 14822 KSSGLTDGIAYEFRVIAENMAGKSKPSKPSEPMLALDPIDPPGKPVPLNITRHTVTLKWA 14881

Query: 765   PPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAG 824
              P++ G   +  Y++E        W+ AN   I + +FT++GL  DA    RV A NAAG
Sbjct: 14882 KPEYTGGFKITSYIVEKRDLPNGRWLKANFSNILENEFTVSGLTEDAAYEFRVIAKNAAG 14941

Query: 825   A-SEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKD 883
             A S P   S  I  ++ +E PKI++    K T I + GEA  L     G+P P + W KD
Sbjct: 14942 AISPPSEPSDAITCRDDVEAPKIKVDVKFKDTVILKAGEAFRLEADVSGRPPPTMEWSKD 15001

Query: 884   GAEIDKN-QINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPP 942
             G E++   ++ I+ ++  T +  + + R  SG Y L             +++++DRPGPP
Sbjct: 15002 GKELEGTAKLEIKIADFSTNLVNKDSTRRDSGAYTLTATNPGGFAKHIFNVKVLDRPGPP 15061

Query: 943   Q-IVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITE 1001
             +  + + +V  E   L+W PP DDG A I  Y +QK +   + W  V      T   +T+
Sbjct: 15062 EGPLAVTEVTSEKCVLSWFPPLDDGGAKIDHYIVQKRETSRLAWTNVASEVQVTKLKVTK 15121

Query: 1002  LVIGNEYYFRVFSENMCGLSE 1022
             L+ GNEY FRV + N  G+ E
Sbjct: 15122 LLKGNEYIFRVMAVNKYGVGE 15142



 Score =  240 bits (613), Expect = 5e-63
 Identities = 159/591 (26%), Positives = 282/591 (47%), Gaps = 40/591 (6%)

Query: 454   DLKPLKILTPLTDQTVNLGKEICLKCEISENIPGK--WTKNGLPVQESDRLKVVHKGRIH 511
             D+KP       +  +V +G+++ ++  IS        WTK+GLP++++ R+ V     + 
Sbjct: 16734 DVKPA-----FSSYSVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLT 16788

Query: 512   KLVIANALTEDEGDYVFAPDAYNVTLPAKVHVI-----DPPK--IILDGLDADNTVTVIA 564
              L I     +D G Y            A + ++     DPPK  +  D + A++      
Sbjct: 16789 TLSIKETHKDDGGQYGITVANVVGQKTASIEIVTLDKPDPPKGPVKFDDVSAES------ 16842

Query: 565   GNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRT-----ESYPDSSTLVIDIAERDDS 619
                    I +S  PP      +    I++      T      +    +TL +   +    
Sbjct: 16843 -------ITLSWNPPLYTGGCQITNYIVQKRDTTTTVWDVVSATVARTTLKVTKLKTGTE 16895

Query: 620   GVYHINLKNEAGEAHASIKVKVV-----DFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGS 674
               + I  +N  G++ A     +V       P PP  P  T +  D  ++ W  P  +GGS
Sbjct: 16896 YQFRIFAENRYGQSFALESDPIVAQYPYKEPGPPGTPFATAISKDSMVIQWHEPVNNGGS 16955

Query: 675   PILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPS 734
             P++GY +ERK++ S  W ++N  +  +T F+ + + EG+ YE R++A N +G+ K S  S
Sbjct: 16956 PVIGYHLERKERNSILWTKVNKTIIHDTQFKAQNLEEGIEYEFRVYAENIVGVGKASKNS 17015

Query: 735   RPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANK 794
               +V      PP       V    +T++W  P + G + + GY++E        W+ A+ 
Sbjct: 17016 ECYVARDPCDPPGTPEPIMVKRNEITLQWTKPVYDGGSMITGYIVEKRDLPDGRWMKASF 17075

Query: 795   DLIDKTKFTITGLPTDAKIFVRVKAVNAAGA-SEPKYYSQPILVKEIIEPPKIRIPRHLK 853
               + +T+FT++GL  D +   RV A NAAGA S+P   + PI  K+ +E P+I +    +
Sbjct: 17076 TNVIETQFTVSGLTEDQRYEFRVIAKNAAGAISKPSDSTGPITAKDEVELPRISMDPKFR 17135

Query: 854   QTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKN-QINIRNSETDTIIFIRKAERSH 912
              T +   GE   L     GKP P + W +   EI+++ +  I+N++   ++ ++ A R  
Sbjct: 17136 DTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRID 17195

Query: 913   SGKYDLQVKVDKFVETASIDIQIIDRPGPPQ-IVKIEDVWGENVALTWTPPKDDGNAAIT 971
              G+Y L+       ++  ++++++DRPGPP+  V++  V  E  +LTW+PP  DG + I+
Sbjct: 17196 GGQYILRASNVAGSKSFPVNVKVLDRPGPPEGPVQVTGVTSEKCSLTWSPPLQDGGSDIS 17255

Query: 972   GYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSE 1022
              Y ++K +   + W  V       S  +T+L+ GNEY FR+ + N  G+ E
Sbjct: 17256 HYVVEKRETSRLAWTVVASEVVTNSLKVTKLLEGNEYVFRIMAVNKYGVGE 17306



 Score =  239 bits (611), Expect = 8e-63
 Identities = 148/495 (29%), Positives = 245/495 (49%), Gaps = 10/495 (2%)

Query: 531   DAYNVTLPAK-VHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDK 589
             D+  VT   K V  +  P++ +D  +   T  V AG  +RL I   G P P A+WS+ D 
Sbjct: 21841 DSCEVTGTIKAVDRLTAPELDIDA-NFKQTHVVRAGASIRLFIAYQGRPTPTAVWSKPDS 21899

Query: 590   AIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPV 649
              +   +    T+S+   STL ++   R+D+G Y + ++N +G    +  VKV+D P PP 
Sbjct: 21900 NLSLRADIHTTDSF---STLTVENCNRNDAGKYTLTVENNSGSKSITFTVKVLDTPGPPG 21956

Query: 650   APTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKM 709
               T  +V      + W+ P  DGG+ I  Y +E+++     W  ++ + C    F+   +
Sbjct: 21957 PITFKDVTRGSATLMWDAPLLDGGARIHHYVVEKREASRRSWQVIS-EKCTRQIFKVNDL 22015

Query: 710   IEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHI 769
              EGV Y  R+ AVN  G+ +P     P V     +PP  L V   + ++  + W  PDH 
Sbjct: 22016 AEGVPYYFRVSAVNEYGVGEPYEMPEPIVATEQPAPPRRLDVVDTSKSSAVLAWLKPDHD 22075

Query: 770   GAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPK 829
             G + + GY+LE   +G++ W+ A      +  FT+  L    +   RVKA N AG SEP+
Sbjct: 22076 GGSRITGYLLEMRQKGSDFWVEAGH--TKQLTFTVERLVEKTEYEFRVKAKNDAGYSEPR 22133

Query: 830   YYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEI-D 888
                  +++KE    P   +     Q    + G    + +P  G+P P++TWK +   + +
Sbjct: 22134 EAFSSVIIKEPQIEPTADLTGITNQLITCKAGSPFTIDVPISGRPAPKVTWKLEEMRLKE 22193

Query: 889   KNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGP-PQIVKI 947
              ++++I  ++  T + ++ + R  SG+Y L ++    V+T S+ + +I RPGP    +++
Sbjct: 22194 TDRVSITTTKDRTTLTVKDSMRGDSGRYFLTLENTAGVKTFSVTVVVIGRPGPVTGPIEV 22253

Query: 948   EDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNE 1007
               V  E+  L+W  PKD G   IT Y ++K +  +  W  V     RT   +T L    E
Sbjct: 22254 SSVSAESCVLSWGEPKDGGGTEITNYIVEKRESGTTAWQLVNSSVKRTQIKVTHLTKYME 22313

Query: 1008  YYFRVFSENMCGLSE 1022
             Y FRV SEN  G+S+
Sbjct: 22314 YSFRVSSENRFGVSK 22328



 Score =  238 bits (608), Expect = 2e-62
 Identities = 155/491 (31%), Positives = 238/491 (48%), Gaps = 15/491 (3%)

Query: 544   IDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESY 603
             ++PP++ILD   A     +  G+ LRL   I G P PK  W + D+   +   + R +  
Sbjct: 10716 LEPPELILDANMAREQ-HIKVGDTLRLSAIIKGVPFPKVTWKKEDR---DAPTKARIDVT 10771

Query: 604   PDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIM 663
             P  S L I  A  +D G+Y + ++N AG    S+KV V+D P PP    V+E+  D C +
Sbjct: 10772 PVGSKLEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLDKPGPPRDLEVSEIRKDSCYL 10831

Query: 664   NWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVN 723
              W+ P  DGGS I  Y +ER+   S++W  L+    K++ F  K + EG  Y  R+ A N
Sbjct: 10832 TWKEPLDDGGSVITNYVVERRDVASAQWSPLSATSKKKSHF-AKHLNEGNQYLFRVAAEN 10890

Query: 724   AIG---ISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLE 780
               G     +   P +   PL    PP  L    V  T V++ W  PD  G + + GY++E
Sbjct: 10891 QYGRGPFVETPKPIKALDPLHPPGPPKDLHHVDVDKTEVSLVWNKPDRDGGSPITGYLVE 10950

Query: 781   YCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEI 840
             Y  EGT+DWI      +   +  +TGL        RVKA N  G   P   + PI  +E 
Sbjct: 10951 YQEEGTQDWI--KFKTVTNLECVVTGLQQGKTYRFRVKAENIVGLGLPD-TTIPIECQEK 11007

Query: 841   IEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQ-INIRNSET 899
             + PP + +   L +  + + G  V      +G P P   W  DG+EI  ++   +     
Sbjct: 11008 LVPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNF 11067

Query: 900   DTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQ-IVKIEDVWGENVALT 958
              +++ I+   R  +G+Y + V      +T ++ + ++D PGPP   + I DV  E++ ++
Sbjct: 11068 SSVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTVLDVPGPPTGPINILDVTPEHMTIS 11127

Query: 959   WTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMC 1018
             W PPKDDG + +  Y ++K D +   W  V     +T   I  L  G EY FRV +EN  
Sbjct: 11128 WQPPKDDGGSPVINYIVEKQDTRKDTWGVVSSGSSKTKLKIPHLQKGCEYVFRVRAENKI 11187

Query: 1019  GLSE--DATMT 1027
             G+    D+T T
Sbjct: 11188 GVGPPLDSTPT 11198



 Score =  238 bits (607), Expect = 2e-62
 Identities = 169/593 (28%), Positives = 282/593 (47%), Gaps = 27/593 (4%)

Query: 266  LKRMRREEKKSAAFA-------KILDPAYQVDKGGR--VRFVVELADPKLEVKWYKNGQE 316
            L   R E  KSAA         +I++P   ++   +  V F  ++    + +KW KNG+E
Sbjct: 6216 LTNHRGENVKSAANLIVEEEDLRIVEPLKDIETMEKKSVTFWCKVNRLNVTLKWTKNGEE 6275

Query: 317  IRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTELFVREPPIMVTKQLEDT 376
            +    +  +     + +L I +C   D+ EY VTAG +K   EL + E P    + LED 
Sbjct: 6276 VPFDNRVSYRVDKYKHMLTIKDCGFPDEGEYIVTAGQDKSVAELLIIEAPTEFVEHLEDQ 6335

Query: 377  TAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAA 436
            T    +     C++S + ANVKW++NG EI  G K  Y+   +G  H LII+     D  
Sbjct: 6336 TVTEFDDAVFSCQLSREKANVKWYRNGREIKEGKK--YKFEKDGSIHRLIIKDCRLDDEC 6393

Query: 437  EYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCEIS-ENIPGKWTKNGLP 495
            EY+      +S A+L V+  P++I+ P  D     G ++    E++ + +  +W +N + 
Sbjct: 6394 EYACGVEDRKSRARLFVEEIPVEIIRPPQDILEAPGADVVFLAELNKDKVEVQWLRNNMV 6453

Query: 496  VQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKIILDGLD 555
            V + D+ +++ +G+IH+L I +    D+G+Y F   A +    AK+ +   PKI      
Sbjct: 6454 VVQGDKHQMMSEGKIHRLQICDIKPRDQGEYRFI--AKDKEARAKLELAAAPKI----KT 6507

Query: 556  ADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAE 615
            AD  + V  G  L + +P    P  +A W + ++ +   +     ++  + ++  I  A+
Sbjct: 6508 ADQDLVVDVGKPLTMVVPYDAYPKAEAEWFKENEPLSTKT----IDTTAEQTSFRILEAK 6563

Query: 616  RDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSP 675
            + D G Y I L+N+ G+A   I +KV+D P P     VTE  D    + WE P  DGGS 
Sbjct: 6564 KGDKGRYKIVLQNKHGKAEGFINLKVIDVPGPVRNLEVTETFDGEVSLAWEEPLTDGGSK 6623

Query: 676  ILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIE-GVAYEVRIFAVNAIGISKPSMPS 734
            I+GY +ER+  +   W+ L  D  +   F    + + GV Y  R+ A N +G  +P    
Sbjct: 6624 IIGYVVERRDIKRKTWV-LATDRAESCEFTVTGLQKGGVEYLFRVSARNRVGTGEPVETD 6682

Query: 735  RPFVPLA---VTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIV 791
             P    +   V  PP  +T+  V    V++ W PP++ G A +  YV+E   + +  W  
Sbjct: 6683 NPVEARSKYDVPGPPLNVTITDVNRFGVSLTWEPPEYDGGAEITNYVIELRDKTSIRWDT 6742

Query: 792  ANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPP 844
            A     +    T+T +    +   RV+A N  G  +P   +  + V + IE P
Sbjct: 6743 AMTVRAEDLSATVTDVVEGQEYSFRVRAQNRIGVGKPSAATPFVKVADPIERP 6795



 Score =  238 bits (607), Expect = 2e-62
 Identities = 172/634 (27%), Positives = 302/634 (47%), Gaps = 44/634 (6%)

Query: 411   KSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVN 470
             K++Y+ R   +  + I   +  +D    +++         LSV +K L         TV 
Sbjct: 12762 KAQYQFRAIARTAVNISPPSEPSDPV--TILAENVPPRIDLSVAMKSLL--------TVK 12811

Query: 471   LGKEICLKCEI-SENIPG-KWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVF 528
              G  +CL   +  + +P   W K+G  ++ ++ +K+  +  +  L + +   +D GDY  
Sbjct: 12812 AGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTI 12871

Query: 529   APDAYNVTLPA--KVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSR 586
               +  + +  A  K+ V+D P     G  A   +  +  ++  L    S EPP +   S 
Sbjct: 12872 TAENSSGSKSATIKLKVLDKP-----GPPASVKINKMYSDRAML----SWEPPLEDGGSE 12922

Query: 587   GDKAIMEGSGRIRTESYPDSSTLVI---DIAERDDSGVYHINL--KNEAGEA-----HAS 636
                 I++     R      S+T+ I    + +  +   Y   +  +N+ G         +
Sbjct: 12923 ITNYIVDKRETSRPNWAQVSATVPITSCSVEKLIEGHEYQFRICAENKYGVGDPVFTEPA 12982

Query: 637   IKVKVVDFP---DPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMR 693
             I     D P   DPPV   +T+   D   ++W+PPA DGGSPI GY +E+++ Q+  W +
Sbjct: 12983 IAKNPYDPPGRCDPPVISNITK---DHMTVSWKPPADDGGSPITGYLLEKRETQAVNWTK 13039

Query: 694   LNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFV---PLAVTSPPTLLT 750
             +N     E T +   + EG  YE R+ A+N  G  KPS  S+      P     PP    
Sbjct: 13040 VNRKPIIERTLKATGLQEGTEYEFRVTAINKAGPGKPSDASKAAYARDPQYPPGPPAFPK 13099

Query: 751   VDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVAN-KDLIDKTKFTITGLPT 809
             V   T ++V++ W  P + G + + GY++E     +++W+  N    + KT+F +TGL  
Sbjct: 13100 VYDTTRSSVSLSWGKPAYDGGSPIIGYLVEVKRADSDNWVRCNLPQNLQKTRFEVTGLME 13159

Query: 810   DAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIP 869
             D +   RV AVN  G S+P         K+I+ PP+  +   L++T I R G  + L +P
Sbjct: 13160 DTQYQFRVYAVNKIGYSDPSDVPDKHYPKDILIPPEGELDADLRKTLILRAGVTMRLYVP 13219

Query: 870   FQGKPRPELTWKKDGAEI-DKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVET 928
              +G+P P++TW K    + D+  ++I++++ DT +      +  +GKY L ++     + 
Sbjct: 13220 VKGRPPPKITWSKPNVNLRDRIGLDIKSTDFDTFLRCENVNKYDAGKYILTLENSCGKKE 13279

Query: 929   ASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTV 988
              +I ++++D PGPP  V ++++  ++  +TW PP  DG + I  Y +QK D +   W TV
Sbjct: 13280 YTIVVKVLDTPGPPVNVTVKEISKDSAYVTWEPPIIDGGSPIINYVVQKRDAERKSWSTV 13339

Query: 989   IEHYHRTSATITELVIGNEYYFRVFSENMCGLSE 1022
                  +TS  +  L  G  Y+FRVF+EN  G+ +
Sbjct: 13340 TTECSKTSFRVANLEEGKSYFFRVFAENEYGIGD 13373



 Score =  238 bits (606), Expect = 3e-62
 Identities = 182/680 (26%), Positives = 309/680 (45%), Gaps = 62/680 (9%)

Query: 389   EVSEDDANVKWFK----NGEEII-------PGPKSRYRIRVEGKKHILIIEGATKADAAE 437
             +VS+  A++ W K     G  ++       P    ++ I  E K    ++ G +     +
Sbjct: 17726 DVSQTSASLMWEKPEHDGGSRVLGYVVEMQPKGTEKWSIVAESKVCNAVVTGLSSGQEYQ 17785

Query: 438   YSVMTTG--GQSSAKL--------SVDLKPLKILTPLTDQTVNLGKEICLKCEI----SE 483
             + V      G+S  ++         + ++P  +  P    ++  G+++ ++  +      
Sbjct: 17786 FRVKAYNEKGKSDPRVLGVPVIAKDLTIQP-SLKLPFNTYSIQAGEDLKIEIPVIGRPRP 17844

Query: 484   NIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAP--DAYNVTLPAKV 541
             NI   W K+G P++++ R+ V        L I     +D G Y       A   T    V
Sbjct: 17845 NI--SWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKYTVTATNSAGTATENLSV 17902

Query: 542   HVIDPP-----KIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSG 596
              V++ P      +  D + AD  V             IS EPP      +    I+E   
Sbjct: 17903 IVLEKPGPPVGPVRFDEVSADFVV-------------ISWEPPAYTGGCQISNYIVEKRD 17949

Query: 597   RIRTESYPDSSTLV---IDIAERDDSGVYHINL--KNEAGE-AHASIKVKVVDFP----D 646
                T  +  S+T+    I I +      Y   +  +N  G+ A    K  +V +P     
Sbjct: 17950 TTTTTWHMVSATVARTTIKITKLKTGTEYQFRIFAENRYGKSAPLDSKAVIVQYPFKEPG 18009

Query: 647   PPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEP 706
             PP  P VT +  D  ++ W  P  DGG+ I+GY +E+K+K S  W++LN    ++T F+ 
Sbjct: 18010 PPGTPFVTSISKDQMLVQWHEPVNDGGTKIIGYHLEQKEKNSILWVKLNKTPIQDTKFKT 18069

Query: 707   KKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPP 766
               + EG+ YE ++ A N +GI KPS  S  FV      PP       +T   VT++W+ P
Sbjct: 18070 TGLDEGLEYEFKVSAENIVGIGKPSKVSECFVARDPCDPPGRPEAIVITRNNVTLKWKKP 18129

Query: 767   DHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAG-A 825
              + G + + GY++E        W+ A+   + +T+FT++GL  D +   RV A NAAG  
Sbjct: 18130 AYDGGSKITGYIVEKKDLPDGRWMKASFTNVLETEFTVSGLVEDQRYEFRVIARNAAGNF 18189

Query: 826   SEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGA 885
             SEP   S  I  ++ I+ P   +    K   +   GE   L    +GKP P++ W KDG 
Sbjct: 18190 SEPSDSSGAITARDEIDAPNASLDPKYKDVIVVHAGETFVLEADIRGKPIPDVVWSKDGK 18249

Query: 886   EIDKN--QINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQ 943
             E+++   ++ I+++   T + ++   R+  G+Y L++      ++  I ++++DRPGPP+
Sbjct: 18250 ELEETAARMEIKSTIQKTTLVVKDCIRTDGGQYILKLSNVGGTKSIPITVKVLDRPGPPE 18309

Query: 944   -IVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITEL 1002
               +K+  V  E   L W PP  DG A I+ Y I+K +   + W  V       +  +T+L
Sbjct: 18310 GPLKVTGVTAEKCYLAWNPPLQDGGANISHYIIEKRETSRLSWTQVSTEVQALNYKVTKL 18369

Query: 1003  VIGNEYYFRVFSENMCGLSE 1022
             + GNEY FRV + N  G+ E
Sbjct: 18370 LPGNEYIFRVMAVNKYGIGE 18389



 Score =  234 bits (598), Expect = 3e-61
 Identities = 141/476 (29%), Positives = 240/476 (50%), Gaps = 11/476 (2%)

Query: 554   LDAD--NTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVI 611
             LDA+   T+ V AG  +R+ +PI G P P+  W++ +  +   +    TES+   + L+I
Sbjct: 14281 LDAELRRTLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINLKNRANIENTESF---TLLII 14337

Query: 612   DIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYD 671
                 R D+G + + ++N AG+    + V+V+D P P +    T++  D   ++W+ P  D
Sbjct: 14338 PECNRYDTGKFVMTIENPAGKKSGFVNVRVLDTPGPVLNLRPTDITKDSVTLHWDLPLID 14397

Query: 672   GGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPS 731
             GGS I  Y +E+++     +       C + T++   + EG  Y  R+ A N  GI +P+
Sbjct: 14398 GGSRITNYIVEKREATRKSYSTATTK-CHKCTYKVTGLSEGCEYFFRVMAENEYGIGEPT 14456

Query: 732   MPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIV 791
               + P       SPP  L +  +T +TV++ W  P H G + + GYV+E   +G++ W  
Sbjct: 14457 ETTEPVKASEAPSPPDSLNIMDITKSTVSLAWPKPKHDGGSKITGYVIEAQRKGSDQW-- 14514

Query: 792   ANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRH 851
              +   +   +  +  L    +   +V AVN+AG S P+  S+P++VKE    P++ +   
Sbjct: 14515 THITTVKGLECVVRNLTEGEEYTFQVMAVNSAGRSAPR-ESRPVIVKEQTMLPELDLRGI 14573

Query: 852   LKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQ-INIRNSETDTIIFIRKAER 910
              ++  I + G+ + + IP  G+P+P +TWKK    + + Q +N   + T TI+ I +  R
Sbjct: 14574 YQKLVIAKAGDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVR 14633

Query: 911   SHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQ-IVKIEDVWGENVALTWTPPKDDGNAA 969
             S SG Y L  +         I IQ+ D PGPP   +K ++V  + V  +W PP++DG   
Sbjct: 14634 SDSGPYPLTARNIVGEVGDVITIQVHDIPGPPTGPIKFDEVSSDFVTFSWDPPENDGGVP 14693

Query: 970   ITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDAT 1025
             I+ Y ++     S  W  +     RT+   T L  G EY FRV ++N  G+    T
Sbjct: 14694 ISNYVVEMRQTDSTTWVELATTVIRTTYKATRLTTGLEYQFRVKAQNRYGVGPGIT 14749



 Score =  233 bits (595), Expect = 6e-61
 Identities = 168/591 (28%), Positives = 280/591 (47%), Gaps = 38/591 (6%)

Query: 453   VDLKPLKILTPLTDQTVNLGKEICLKCEISENIPGKWTKNGLPVQESDRLKVVHKGRIHK 512
             +DLK   +LT     T+ L  E  ++ +    +     K+   +  S R+K+  +    K
Sbjct: 11706 LDLKLSGVLTVKAGDTIRL--EAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSK 11763

Query: 513   LVIANALTEDEGDYVFAPD--AYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRL 570
               +  A   D G YV      A +    A V+V+D P     G   +  +  ++ ++   
Sbjct: 11764 FSLTKAKRSDGGKYVVTATNTAGSFVAYATVNVLDKP-----GPVRNLKIVDVSSDRCT- 11817

Query: 571   EIPISGEPPPKAMWSRGDKAIMEG--SGRIRTESYPDS----STLVIDIAERDDSGVYHI 624
                +  +PP           I+E   + R+   +Y  +     T V  + E ++  ++ +
Sbjct: 11818 ---VCWDPPEDDGGCEIQNYILEKCETKRMVWSTYSATVLTPGTTVTRLIEGNEY-IFRV 11873

Query: 625   NLKNEAG-----EAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGY 679
               +N+ G     E+   I     D P  P  P VT+V  +   + W PP YDGG  I GY
Sbjct: 11874 RAENKIGTGPPTESKPVIAKTKYDKPGRPDPPEVTKVSKEEMTVVWNPPEYDGGKSITGY 11933

Query: 680   FIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFV- 738
             F+E+K+K S+RW+ +N     E   + + ++    Y+ R+ A N IGI +PS+PSRP V 
Sbjct: 11934 FLEKKEKHSTRWVPVNKSAIPERRMKVQNLLPDHEYQFRVKAENEIGIGEPSLPSRPVVA 11993

Query: 739   --PLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYC-----FEGTEDWIV 791
               P+    PPT   V   T  ++T+ W  P + G A + GYV+E           E W  
Sbjct: 11994 KDPIEPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAPIIGYVVEMRPKIADASPDEGWKR 12053

Query: 792   ANKDL-IDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPR 850
              N    + + +FT+T L  + +   RV A N  G   P    + I  KEI+EPP+I +  
Sbjct: 12054 CNAAAQLVRKEFTVTSLDENQEYEFRVCAQNQVGIGRPAELKEAIKPKEILEPPEIDLDA 12113

Query: 851   HLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAE--IDKNQINIRNSETDTIIFIRKA 908
              +++  I R G  + L    +G+P P++TW+K G +  + K Q+++   +T   + I  +
Sbjct: 12114 SMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDNVVRKGQVDL--VDTMAFLVIPNS 12171

Query: 909   ERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNA 968
              R  SGKY L +      +   ++++++D PGP   +K+ DV   +  ++W PP++DG +
Sbjct: 12172 TRDDSGKYSLTLVNPAGEKAVFVNVRVLDTPGPVSDLKVSDVTKTSCHVSWAPPENDGGS 12231

Query: 969   AITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCG 1019
              +T Y ++K +     W TV     +TS  +T LV GNEYYFRV + N  G
Sbjct: 12232 QVTHYIVEKREADRKTWSTVTPEVKKTSFHVTNLVPGNEYYFRVTAVNEYG 12282



 Score =  233 bits (594), Expect = 8e-61
 Identities = 159/513 (30%), Positives = 252/513 (49%), Gaps = 34/513 (6%)

Query: 545  DPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWS---RGDKAIMEGSGRI--- 598
            + P++ +D + A + +   AG+++R+   I G P PK+ W    +  KA+ +G   I   
Sbjct: 9309 EEPEVFID-IGAQDCLVCKAGSQIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPED 9367

Query: 599  -RTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVG 657
             + E+  +SS ++I   +R  +G Y I  KN+AG+  A+ +VKV+D P PP    V+++ 
Sbjct: 9368 AQLETAENSSVIIIPECKRSHTGKYSITAKNKAGQKTANCRVKVMDVPGPPKDLKVSDIT 9427

Query: 658  DDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEV 717
               C ++W+ P  DGG  I GY IE++      W ++N D C  TTF    ++    Y  
Sbjct: 9428 RGSCRLSWKMPDDDGGDRIKGYVIEKRTIDGKAWTKVNPD-CGSTTFVVPDLLSEQQYFF 9486

Query: 718  RIFAVNAIGISKPSMPSRPFV---PLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGL 774
            R+ A N  GI  P    +      P+    PP  L +  +T  TV + W+PP + G + +
Sbjct: 9487 RVRAENRFGIGPPVETIQRTTARDPIYPPDPPIKLKIGLITKNTVHLSWKPPKNDGGSPV 9546

Query: 775  DGYVLEYCF----EGT--EDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEP 828
              Y++E C      GT  E W   NK  +++ +FT+  L    +   RVKAVNAAG S+P
Sbjct: 9547 THYIVE-CLAWDPTGTKKEAWRQCNKRDVEELQFTVEDLVEGGEYEFRVKAVNAAGVSKP 9605

Query: 829  KYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTW------KK 882
                 P   +    PP I     LK+      G  VN+V   +G P P LTW      K 
Sbjct: 9606 SATVGPCDCQRPDMPPSI----DLKEFMEVEEGTNVNIVAKIKGVPFPTLTWFKAPPKKP 9661

Query: 883  DGAE---IDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRP 939
            D  E    D +   +   +T T++ I ++ RS +G Y +    +    +  + + ++ RP
Sbjct: 9662 DNKEPVLYDTHVNKLVVDDTCTLV-IPQSRRSDTGLYTITAVNNLGTASKEMRLNVLGRP 9720

Query: 940  GPP-QIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSAT 998
            GPP   +K E V  + + L+W PPKDDG + IT Y I+K +     W  V       + T
Sbjct: 9721 GPPVGPIKFESVSADQMTLSWFPPKDDGGSKITNYVIEKREANRKTWVHVSSEPKECTYT 9780

Query: 999  ITELVIGNEYYFRVFSENMCGLSEDATMTKESA 1031
            I +L+ G+EY FR+ ++N  G+ E      E+A
Sbjct: 9781 IPKLLEGHEYVFRIMAQNKYGIGEPLDSEPETA 9813



 Score =  230 bits (587), Expect = 5e-60
 Identities = 156/568 (27%), Positives = 267/568 (47%), Gaps = 24/568 (4%)

Query: 490   TKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKI 549
             +++G+P++ + R           + +  ++T D G Y       + T  A ++++     
Sbjct: 20014 SRDGVPLKATMRFNTEITAENLTINLKESVTADAGRYEITAANSSGTTKAFINIV----- 20068

Query: 550   ILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIM---EGSGRIRTESYPDS 606
             +LD      T  V+  +     + +  EPP     S+    I+   E S  + TE     
Sbjct: 20069 VLDR-PGPPTGPVVISDITEESVTLKWEPPKYDGGSQVTNYILLKRETSTAVWTEVSATV 20127

Query: 607   STLVIDIAERDDSGVYHINLKNE--------AGEAHASIKVKVVDFPDPPVAPTVTEVGD 658
             +  ++ + +      Y   +K E           A  ++K+     P PP  P VT V  
Sbjct: 20128 ARTMMKVMKLTTGEEYQFRIKAENRFGISDHIDSACVTVKLPYTT-PGPPSTPWVTNVTR 20186

Query: 659   DWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVR 718
             +   + W  P  +GGS ++GY +E K + S  W + N  + + T F+   +  G+ YE R
Sbjct: 20187 ESITVGWHEPVSNGGSAVVGYHLEMKDRNSILWQKANKLVIRTTHFKVTTISAGLIYEFR 20246

Query: 719   IFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYV 778
             ++A NA G+ KPS PS P + +    PP  + +  ++  +V++ W+ P   G + + GY+
Sbjct: 20247 VYAENAAGVGKPSHPSEPVLAIDACEPPRNVRITDISKNSVSLSWQQPAFDGGSKITGYI 20306

Query: 779   LEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGA-SEPKYYSQPILV 837
             +E        W  A+   + +T+F I+GL  +++   RV A NA G+ S P     PI  
Sbjct: 20307 VERRDLPDGRWTKASFTNVTETQFIISGLTQNSQYEFRVFARNAVGSISNPSEVVGPITC 20366

Query: 838   KEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNS 897
              +    P I +P    +    R G +V L     GKP P + W KD  E+  N +    +
Sbjct: 20367 IDSYGGPVIDLPLEYTEVVKYRAGTSVKLRAGISGKPAPTIEWYKDDKELQTNALVCVEN 20426

Query: 898   ETD-TIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPP-QIVKIEDVWGENV 955
              TD   I I+ A+R +SG Y+L+++      +A+I +QI+D+PGPP   ++ + V  E +
Sbjct: 20427 TTDLASILIKDADRLNSGCYELKLRNAMGSASATIRVQILDKPGPPGGPIEFKTVTAEKI 20486

Query: 956   ALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSE 1015
              L W PP DDG A IT Y ++K +   + W  V EH      T T+++ GNEY FRV + 
Sbjct: 20487 TLLWRPPADDGGAKITHYIVEKRETSRVVWSMVSEHLEECIITTTKIIKGNEYIFRVRAV 20546

Query: 1016  NMCGLSEDATMTKESAVIARDGKIYKNP 1043
             N  G+ E     +  +V+A++  +   P
Sbjct: 20547 NKYGIGEP---LESDSVVAKNAFVTPGP 20571



 Score =  230 bits (586), Expect = 7e-60
 Identities = 161/526 (30%), Positives = 248/526 (47%), Gaps = 48/526 (9%)

Query: 545  DPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYP 604
            + P+I LD +     +TV AG K+ L   ++G+P PK  W++ D  I++   RI  E+ P
Sbjct: 7189 EAPEIFLD-VKLLAGLTVKAGTKIELPATVTGKPEPKITWTKADM-ILKQDKRITIENVP 7246

Query: 605  DSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMN 664
              ST+ I  ++R D+G Y I   N  G A A ++V V+D P PP A  +T+V ++ C++ 
Sbjct: 7247 KKSTVTIVDSKRSDTGTYIIEAVNVCGRATAVVEVNVLDKPGPPAAFDITDVTNESCLLT 7306

Query: 665  WEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNA 724
            W PP  DGGS I  Y +ER+   S  W +L+    K+T F+  K+I    Y  R+ A N 
Sbjct: 7307 WNPPRDDGGSKITNYVVERRATDSEVWHKLS-STVKDTNFKATKLIPNKEYIFRVAAENM 7365

Query: 725  IGISKP--SMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYC 782
             G+ +P  + P           PPT L    +T   VT+ W  PD  G + + GY +E  
Sbjct: 7366 YGVGEPVQASPITAKYQFDPPGPPTRLEPSDITKDAVTLTWCEPDDDGGSPITGYWVERL 7425

Query: 783  FEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIE 842
               T+ W+  NK  +  T + + GL    K   RV A N AG  +P   ++PIL+K+ I+
Sbjct: 7426 DPDTDKWVRCNKMPVKDTTYRVKGLTNKKKYRFRVLAENLAGPGKPSKSTEPILIKDPID 7485

Query: 843  PPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKK----DGAEIDKNQINIRNSE 898
            PP       +K                  GK    L W K     GA+I+   I +  + 
Sbjct: 7486 PPWPPGKPTVKDV----------------GKTSVRLNWTKPEHDGGAKIESYVIEMLKTG 7529

Query: 899  TDTIIFIRKAE-----------RSHSGKYDLQVK-VDKFVETASID-------IQIIDRP 939
            TD   ++R AE                +Y  +V+ V+K  E+   +        + +  P
Sbjct: 7530 TDE--WVRVAEGVPTTQHLLPGLMEGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPP 7587

Query: 940  GPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATI 999
             PP+ +++ ++      L WT P+ DG + IT Y ++K D +   W TV      T  T+
Sbjct: 7588 SPPRWLEVINITKNTADLKWTVPEKDGGSPITNYIVEKRDVRRKGWQTVDTTVKDTKCTV 7647

Query: 1000 TELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVY 1045
            T L  G+ Y FRV +EN  G S+   +  E +V+A+D      P Y
Sbjct: 7648 TPLTEGSLYVFRVAAENAIGQSDYTEI--EDSVLAKDTFTTPGPPY 7691



 Score =  230 bits (586), Expect = 7e-60
 Identities = 154/553 (27%), Positives = 257/553 (46%), Gaps = 32/553 (5%)

Query: 489   WTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVF--APDAYNVTLPAKVHVIDP 546
             W K+G  ++E+ R+ V     +  L I  A  ED G Y    +  A ++T+P  + V+D 
Sbjct: 18931 WRKDGQTLKETTRVNVSSSKTVTSLSIKEASKEDVGTYELCVSNSAGSITVPITIIVLDR 18990

Query: 547   P----KIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTES 602
             P     I +D +  D+             I IS  PP      +    I+E      T  
Sbjct: 18991 PGPPGPIRIDEVSCDS-------------ITISWNPPEYDGGCQISNYIVEKKETTSTTW 19037

Query: 603   YPDSSTLV---IDIAERDDSGVYHINL-------KNEAGEAHASIKVKVVDFPDPPVAPT 652
             +  S  +    I I        Y   +       K+   E+ A +       P PP  P 
Sbjct: 19038 HIVSQAVARTSIKIVRLTTGSEYQFRVCAENRYGKSSYSESSAVVAEYPFSPPGPPGTPK 19097

Query: 653   VTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEG 712
             V        ++ W+ P  DGGS ++GY +E K++ S  W + N  L  +T  +   + EG
Sbjct: 19098 VVHATKSTMLVTWQVPVNDGGSRVIGYHLEYKERSSILWSKANKILIADTQMKVSGLDEG 19157

Query: 713   VAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAA 772
             + YE R++A N  GI K S    P        PP    V ++T  +V+++W  P + G A
Sbjct: 19158 LMYEYRVYAENIAGIGKCSKSCEPVPARDPCDPPGQPEVTNITRKSVSLKWSKPHYDGGA 19217

Query: 773   GLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAA-GASEPKYY 831
              + GY++E        W+  N   I +T F +T L  D +   RV A NAA   SEP   
Sbjct: 19218 KITGYIVERRELPDGRWLKCNYTNIQETYFEVTELTEDQRYEFRVFARNAADSVSEPSES 19277

Query: 832   SQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKN- 890
             + PI+VK+ +EPP++ +    +   + + GE + +     G+P P ++W KDG EI++  
Sbjct: 19278 TGPIIVKDDVEPPRVMMDVKFRDVIVVKAGEVLKINADIAGRPLPVISWAKDGIEIEERA 19337

Query: 891   QINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQ-IVKIED 949
             +  I +++  T++ ++   R  +G+Y L +K      + +++ +++D+PGPP   ++I  
Sbjct: 19338 RTEIISTDNHTLLTVKDCIRRDTGQYVLTLKNVAGTRSVAVNCKVLDKPGPPAGPLEING 19397

Query: 950   VWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYY 1009
             +  E  +L+W  P++DG A I  Y ++K +   + W         TS  +T+L+ GNEY 
Sbjct: 19398 LTAEKCSLSWGRPQEDGGADIDYYIVEKRETSHLAWTICEGELQMTSCKVTKLLKGNEYI 19457

Query: 1010  FRVFSENMCGLSE 1022
             FRV   N  G+ E
Sbjct: 19458 FRVTGVNKYGVGE 19470



 Score =  229 bits (583), Expect = 1e-59
 Identities = 169/620 (27%), Positives = 271/620 (43%), Gaps = 26/620 (4%)

Query: 419   EGKKHILIIEGATKADAAEYSVMTTGGQSSAKL-SVDLKPLKILTPLTDQTVNLGKEICL 477
             EGK++   +    +      S +T   +       +DLK L  L  L  +  N   +I +
Sbjct: 13450 EGKEYTFRVSAENENGEGTPSEITVVARDDVVAPDLDLKGLPDLCYLAKENSNFRLKIPI 13509

Query: 478   KCEISENIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTL 537
             K + + ++   W K   P+    R+ V        L++ +    D G Y         T 
Sbjct: 13510 KGKPAPSV--SWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTK 13567

Query: 538   PA--KVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGS 595
                  + V+  P I    +  D  VT  A       + +   PP     S     I+E  
Sbjct: 13568 EGTISIKVVGKPGIPTGPIKFDE-VTAEA-------MTLKWAPPKDDGGSEITNYILEKR 13619

Query: 596   GRIRTE-----SYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVV-----DFP 645
               +  +     S    +T  +          + ++ +N+ G         +V     D P
Sbjct: 13620 DSVNNKWVTCASAVQKTTFRVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVP 13679

Query: 646   DPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFE 705
             D P  P + +V  D   + W  P   GGSPI GY +E K++ S  W R N    +   F+
Sbjct: 13680 DAPPPPNIVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTPIRMRDFK 13739

Query: 706   PKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRP 765
                + EG+ YE R+ A+N  G+ KPS+PS P V L    PP    V ++T  +VT+ W  
Sbjct: 13740 VTGLTEGLEYEFRVMAINLAGVGKPSLPSEPVVALDPIDPPGKPEVINITRNSVTLIWTE 13799

Query: 766   PDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGA 825
             P + G   L GY++E     ++ W+ AN   + +  FT+T L    K   R++A N AGA
Sbjct: 13800 PKYDGGHKLTGYIVEKRDLPSKSWMKANHVNVPECAFTVTDLVEGGKYEFRIRAKNTAGA 13859

Query: 826   -SEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNL-VIPFQGKPRPELTWKKD 883
              S P   ++ I+ K+  E P I +   +K     + G+ + L  I   GKP P+ +W K 
Sbjct: 13860 ISAPSESTETIICKDEYEAPTIVLDPTIKDGLTIKAGDTIVLNAISILGKPLPKSSWSKA 13919

Query: 884   GAEIDKNQI-NIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPP 942
             G +I  + I  I ++ T +++ I+ A R  +G+Y +        +   + + ++D PGPP
Sbjct: 13920 GKDIRPSDITQITSTPTSSMLTIKYATRKDAGEYTITATNPFGTKVEHVKVTVLDVPGPP 13979

Query: 943   QIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITEL 1002
               V+I +V  E   LTWTPP +DG + I  Y ++K +   + W  V E         T+L
Sbjct: 13980 GPVEISNVSAEKATLTWTPPLEDGGSPIKSYILEKRETSRLLWTVVSEDIQSCRHVATKL 14039

Query: 1003  VIGNEYYFRVFSENMCGLSE 1022
             + GNEY FRV + N  G  E
Sbjct: 14040 IQGNEYIFRVSAVNHYGKGE 14059



 Score =  228 bits (580), Expect = 3e-59
 Identities = 170/617 (27%), Positives = 288/617 (46%), Gaps = 47/617 (7%)

Query: 453   VDLKPLKILTPLTDQTV-NLGKEICLKCEISENIPG--KWTKNGLPVQESDRLKVVHKGR 509
             V+   +K+     D  +   G+   L+ ++S   P   +W+K+G  ++ + +L++     
Sbjct: 14959 VEAPKIKVDVKFKDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADF 15018

Query: 510   IHKLVIANALTEDEGDYV--------FAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVT 561
                LV  ++   D G Y         FA   +NV       V+D P       +    VT
Sbjct: 15019 STNLVNKDSTRRDSGAYTLTATNPGGFAKHIFNVK------VLDRP----GPPEGPLAVT 15068

Query: 562   VIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIR-----TESYPDSSTLVIDIAER 616
              +   K  L    S  PP     ++ D  I++     R       S    + L +    +
Sbjct: 15069 EVTSEKCVL----SWFPPLDDGGAKIDHYIVQKRETSRLAWTNVASEVQVTKLKVTKLLK 15124

Query: 617   DDSGVYHINLKNEAG-----EAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYD 671
              +  ++ +   N+ G     E+   + V     PDPP  P VT +  D  ++ W  P  D
Sbjct: 15125 GNEYIFRVMAVNKYGVGEPLESEPVLAVNPYGPPDPPKNPEVTTITKDSMVVCWGHPDSD 15184

Query: 672   GGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPS 731
             GGS I+ Y +ER+ K   RW++ N     +  ++   + EG  YE RI A NA GIS PS
Sbjct: 15185 GGSEIINYIVERRDKAGQRWIKCNKKTLTDLRYKVSGLTEGHEYEFRIMAENAAGISAPS 15244

Query: 732   MPSRPFVPLAVT----SPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTE 787
              P+ PF     T     PP    V   + +++++ W  P + G + + GY++E      +
Sbjct: 15245 -PTSPFYKACDTVFKPGPPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIALPEED 15303

Query: 788   DW-IVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKI 846
             +W IV     +  T +TITGL  + +  +R+ A+N+ G  EP         ++ + PP+I
Sbjct: 15304 EWQIVTPPAGLKATSYTITGLTENQEYKIRIYAMNSEGLGEPALVPGTPKAEDRMLPPEI 15363

Query: 847   RIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKD-GAEIDKNQINIRNSETDTIIFI 905
              +   L++    R    + L +P +G+P PE+ W +D G  +DK   +I ++ + T++ +
Sbjct: 15364 ELDADLRKVVTIRACCTLRLFVPIKGRPAPEVKWARDHGESLDK--ASIESTSSYTLLIV 15421

Query: 906   RKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDD 965
                 R  SGKY L V+     ++A ++++++D PGPPQ +K+++V   +V LTW PP  D
Sbjct: 15422 GNVNRFDSGKYILTVENSSGSKSAFVNVRVLDTPGPPQDLKVKEVTKTSVTLTWDPPLLD 15481

Query: 966   GNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGL---SE 1022
             G + I  Y ++K +     + TV  + H+TS  + +L  G  YYFRV +EN  G+   +E
Sbjct: 15482 GGSKIKNYIVEKRESTRKAYSTVATNCHKTSWKVDQLQEGCSYYFRVLAENEYGIGLPAE 15541

Query: 1023  DATMTKESAVIARDGKI 1039
              A   K S      GKI
Sbjct: 15542 TAESVKASERPLPPGKI 15558



 Score =  228 bits (580), Expect = 3e-59
 Identities = 151/547 (27%), Positives = 256/547 (46%), Gaps = 24/547 (4%)

Query: 489   WTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPD--AYNVTLPAKVHVIDP 546
             W K+GLP++ES+ ++         L I NA  E  G Y    D     + +P  V  + P
Sbjct: 21100 WLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHGGKYTVILDNAVCRIAVPITVITLGP 21159

Query: 547   PK-----IILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTE 601
             P      I  D + AD+ +       L  ++P          +S   +   + + ++   
Sbjct: 21160 PSKPKGPIRFDEIKADSVI-------LSWDVPEDNGGGEITCYSIEKRETSQTNWKMVCS 21212

Query: 602   SYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVD-----FPDPPVAPTVTEV 656
             S   ++  V ++  +D    + +  +N  G +   +   +V       P PP  P +  V
Sbjct: 21213 SVARTTFKVPNLV-KDAEYQFRVRAENRYGVSQPLVSSIIVAKHQFRIPGPPGKPVIYNV 21271

Query: 657   GDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYE 716
               D   + W+ P YDGGS + G+ +E+K++ S  W ++N        +    ++EG+ Y+
Sbjct: 21272 TSDGMSLTWDAPVYDGGSEVTGFHVEKKERNSILWQKVNTSPISGREYRATGLVEGLDYQ 21331

Query: 717   VRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDG 776
              R++A N+ G+S PS PS+  + ++   PP       VT  T+T++W PP   G + + G
Sbjct: 21332 FRVYAENSAGLSSPSDPSKFTLAVSPVDPPGTPDYIDVTRETITLKWNPPLRDGGSKIVG 21391

Query: 777   YVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGA-SEPKYYSQPI 835
             Y +E   +G E W+  N   + + ++T+TGL    +   R+ A NA G  S P   S  I
Sbjct: 21392 YSIEK-RQGNERWVRCNFTDVSECQYTVTGLSPGDRYEFRIIARNAVGTISPPSQSSGII 21450

Query: 836   LVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKN-QINI 894
             + ++   PP +          I + GE++ +    QG+P P +TW KDG EI+K   + I
Sbjct: 21451 MTRDENVPPIVEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNMEI 21510

Query: 895   RNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGP-PQIVKIEDVWGE 953
              +    T +F+R A R H G Y ++ K       A I +++ D PG     ++  ++ GE
Sbjct: 21511 TDVLGSTSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQDTPGKVVGPIRFTNITGE 21570

Query: 954   NVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVF 1013
              + L W  P +DG A IT Y I+K +   + W  + +     S T  +L+ GNEY FRV 
Sbjct: 21571 KMTLWWDAPLNDGCAPITHYIIEKRETSRLAWALIEDKCEAQSYTAIKLINGNEYQFRVS 21630

Query: 1014  SENMCGL 1020
             + N  G+
Sbjct: 21631 AVNKFGV 21637



 Score =  227 bits (578), Expect = 6e-59
 Identities = 154/500 (30%), Positives = 249/500 (49%), Gaps = 18/500 (3%)

Query: 530   PDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDK 589
             P   N  + AK  +++ P+I LD +    +V   AG  +++ IP  G PPP   W R D+
Sbjct: 20756 PIEMNEPVQAK-DILEAPEIDLD-VALRTSVIAKAGEDVQVLIPFKGRPPPTVTW-RKDE 20812

Query: 590   AIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHAS-IKVKVVDFPDPP 648
               +    R   E+   SS L I    R+D+G Y + ++N  GE  +S + VKV+D P   
Sbjct: 20813 KNLGSDARYSIENTDSSSLLTIPQVTRNDTGKYILTIENGVGEPKSSTVSVKVLDTPAAC 20872

Query: 649   VAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKK 708
                 V  V      + W+PP  DGGSPI+ Y IE++      W  ++   C  T+F+   
Sbjct: 20873 QKLQVKHVSRGTVTLLWDPPLIDGGSPIINYVIEKRDATKRTWSVVSHK-CSSTSFKLID 20931

Query: 709   MIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDH 768
             + E   +  R+ A N IGI +P   + P     V +P   L++   T T+V + W  PD 
Sbjct: 20932 LSEKTPFFFRVLAENEIGIGEPCETTEPVKAAEVPAPIRDLSMKDSTKTSVILSWTKPDF 20991

Query: 769   IGAAGLDGYVLEYCFEGTEDWIVANKDLIDKT-KFTITGLPTDAKIFVRVKAVNAAGASE 827
              G + +  YV+E   +G + W  A    I KT +  ++ L   + +  RV A N  G S+
Sbjct: 20992 DGGSVITEYVVERKGKGEQTWSHAG---ISKTCEIEVSQLKEQSVLEFRVFAKNEKGLSD 21048

Query: 828   PKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEI 887
             P     PI VKE+I  P++ +          R+G  V+L +P++GKP+P ++W KDG  +
Sbjct: 21049 PVTIG-PITVKELIITPEVDLSDIPGAQVTVRIGHNVHLELPYKGKPKPSISWLKDGLPL 21107

Query: 888   DKNQ-INIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQI-- 944
              +++ +    +E    + I+ A++ H GKY   V +D  V   ++ I +I   GPP    
Sbjct: 21108 KESEFVRFSKTENKITLSIKNAKKEHGGKYT--VILDNAVCRIAVPITVITL-GPPSKPK 21164

Query: 945   --VKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITEL 1002
               ++ +++  ++V L+W  P+D+G   IT Y+I+K +     W  V     RT+  +  L
Sbjct: 21165 GPIRFDEIKADSVILSWDVPEDNGGGEITCYSIEKRETSQTNWKMVCSSVARTTFKVPNL 21224

Query: 1003  VIGNEYYFRVFSENMCGLSE 1022
             V   EY FRV +EN  G+S+
Sbjct: 21225 VKDAEYQFRVRAENRYGVSQ 21244



 Score =  226 bits (576), Expect = 1e-58
 Identities = 163/554 (29%), Positives = 261/554 (47%), Gaps = 33/554 (5%)

Query: 489   WTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYV--FAPDAYNVTLPAKVHVIDP 546
             W K+ +P++++ R+          L I +A  ED G YV      A        V V+D 
Sbjct: 15684 WHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAGEAIETLNVIVLDK 15743

Query: 547   P-----KIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTE 601
             P      + +D + AD+             I +S  PP     S  +  I+E      T 
Sbjct: 15744 PGPPTGPVKMDEVTADS-------------ITLSWGPPKYDGGSSINNYIVEKRDTSTTT 15790

Query: 602   SYPDSSTLVIDI--AERDDSGV---YHINLKNEAGEA-HASIKVKVVDF----PDPPVAP 651
                 S+T+      A R  +G    + I  +N  G++ + + +  V  +    P PP  P
Sbjct: 15791 WQIVSATVARTTIKACRLKTGCEYQFRIAAENRYGKSTYLNSEPTVAQYPFKVPGPPGTP 15850

Query: 652   TVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIE 711
              VT    D   + W  P  DGGS ++GY +ERK++ S  W++LN     +T F+   + E
Sbjct: 15851 VVTLSSRDSMEVQWNEPISDGGSRVIGYHLERKERNSILWVKLNKTPIPQTKFKTTGLEE 15910

Query: 712   GVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGA 771
             GV YE R+ A N +GI KPS  S  +V      PP       VT  +VT++W+ P + G 
Sbjct: 15911 GVEYEFRVSAENIVGIGKPSKVSECYVARDPCDPPGRPEAIIVTRNSVTLQWKKPTYDGG 15970

Query: 772   AGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGA-SEPKY 830
             + + GY++E        W+ A+   I  T F +TGL  D +   RV A NAAG  SEP  
Sbjct: 15971 SKITGYIVEKKELPEGRWMKASFTNIIDTHFEVTGLVEDHRYEFRVIARNAAGVFSEPSE 16030

Query: 831   YSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKN 890
              +  I  ++ ++PP+I +    K T +   GE+  +     GKP P + W K   E+   
Sbjct: 16031 STGAITARDEVDPPRISMDPKYKDTIVVHAGESFKVDADIYGKPIPTIQWIKGDQELSNT 16090

Query: 891   -QINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQ-IVKIE 948
              ++ I++++  T + ++ A R  SG Y L+ K      + +++++++DRPGPP+  V I 
Sbjct: 16091 ARLEIKSTDFATSLSVKDAVRVDSGNYILKAKNVAGERSVTVNVKVLDRPGPPEGPVVIS 16150

Query: 949   DVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEY 1008
              V  E   L W PP  DG + I  Y +++ +   + W  V  +    S  +T+L+ GNEY
Sbjct: 16151 GVTAEKCTLAWKPPLQDGGSDIINYIVERRETSRLVWTVVDANVQTLSCKVTKLLEGNEY 16210

Query: 1009  YFRVFSENMCGLSE 1022
              FR+ + N  G+ E
Sbjct: 16211 TFRIMAVNKYGVGE 16224



 Score =  225 bits (574), Expect = 2e-58
 Identities = 142/476 (29%), Positives = 224/476 (47%), Gaps = 18/476 (3%)

Query: 598   IRTESYPDSSTLVIDIAERDDSGVYHINLKNEAG-----EAHASIKVKVVDFPDPPVAPT 652
             +   S P   T  I         V+ I  +N+ G     ++       +   P  P  PT
Sbjct: 9768  VHVSSEPKECTYTIPKLLEGHEYVFRIMAQNKYGIGEPLDSEPETARNLFSVPGAPDKPT 9827

Query: 653   VTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETT----FEPKK 708
             V+ V  +   +NWE P YDGGSP+ GY++E K   S RW R+N D  K  T    ++   
Sbjct: 9828  VSSVTRNSMTVNWEEPEYDGGSPVTGYWLEMKDTTSKRWKRVNRDPIKAMTLGVSYKVTG 9887

Query: 709   MIEGVAYEVRIFAVNAIGISKPSMPSRPFV---PLAVTSPPTLLTVDSVTDTTVTMRWRP 765
             +IEG  Y+ R++A+NA G+   S+PS P     P+A   PP     D  T ++  + W P
Sbjct: 9888  LIEGSDYQFRVYAINAAGVGPASLPSDPATARDPIAPPGPPFPKVTDW-TKSSADLEWSP 9946

Query: 766   PDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGA 825
             P   G + + GY++EY  EG E+W       +  TK  +TGL   A    RV+AVN AG 
Sbjct: 9947  PLKDGGSKVTGYIVEYKEEGKEEWEKGKDKEVRGTKLVVTGLKEGAFYKFRVRAVNIAGI 10006

Query: 826   SEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGA 885
              EP   +  I +K+ +  P +++   ++   +   G  + ++    GKP P +TW  +  
Sbjct: 10007 GEPGEVTDVIEMKDRLVSPDLQLDASVRDRIVVHAGGVIRIIAYVSGKPPPTVTWNMNER 10066

Query: 886   EIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIV 945
              + + +  I  +   + + I+  +RSH G Y L  K +      +I + ++D PGP    
Sbjct: 10067 TLPQ-EATIETTAISSSMVIKNCQRSHQGVYSLLAKNEAGERKKTIIVDVLDVPGPVGTP 10125

Query: 946   KI-EDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVI 1004
              +  ++  E+  LTW  P+DDG + IT Y I+K +     W  V     R +AT+  L+ 
Sbjct: 10126 FLAHNLTNESCKLTWFSPEDDGGSPITNYVIEKRESDRRAWTPVTYTVTRQNATVQGLIQ 10185

Query: 1005  GNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPL 1060
             G  Y+FR+ +EN  G+      T E+ VI     + + P  ED +  E    T  L
Sbjct: 10186 GKAYFFRIAAENSIGMG-PFVETSEALVIREPITVPERP--EDLEVKEVTKNTVTL 10238



 Score =  223 bits (569), Expect = 6e-58
 Identities = 160/574 (27%), Positives = 265/574 (46%), Gaps = 34/574 (5%)

Query: 488   KWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNV----TLPAKVHV 543
             +W K    +  + RL++        L + +A+  D G+Y+    A NV    ++   V V
Sbjct: 16079 QWIKGDQELSNTARLEIKSTDFATSLSVKDAVRVDSGNYILK--AKNVAGERSVTVNVKV 16136

Query: 544   IDPP-----KIILDGLDADNTVTVIA-----GNKLRLEIPISGEPPPKAMWSRGDKAIME 593
             +D P      +++ G+ A+            G    +   +      + +W+  D  +  
Sbjct: 16137 LDRPGPPEGPVVISGVTAEKCTLAWKPPLQDGGSDIINYIVERRETSRLVWTVVDANVQT 16196

Query: 594   GSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTV 653
              S ++      +  T  I    +   G        E  E+   +       PD P AP V
Sbjct: 16197 LSCKVTKLLEGNEYTFRIMAVNKYGVG--------EPLESEPVVAKNPFVVPDAPKAPEV 16248

Query: 654   TEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGV 713
             T V  D  I+ WE PA DGGS ILGY +E++ K+  RW R +  L  E       +IE  
Sbjct: 16249 TTVTKDSMIVVWERPASDGGSEILGYVLEKRDKEGIRWTRCHKRLIGELRLRVTGLIENH 16308

Query: 714   AYEVRIFAVNAIGISKPSMPS---RPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIG 770
              YE R+ A NA G+S+PS PS   +   P+    PP    V  +T ++V + W  P + G
Sbjct: 16309 DYEFRVSAENAAGLSEPSPPSAYQKACDPIYKPGPPNNPKVIDITRSSVFLSWSKPIYDG 16368

Query: 771   AAGLDGYVLEYCFEGTEDWIVANKDL-IDKTKFTITGLPTDAKIFVRVKAVNAAGASEPK 829
                + GY++E C     +W +      I+KT   +  L    +   R+ A+N AG  E  
Sbjct: 16369 GCEIQGYIVEKCDVSVGEWTMCTPPTGINKTNIEVEKLLEKHEYNFRICAINKAGVGEHA 16428

Query: 830   YYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTW-KKDGAEID 888
                 PI+V+E +E P I +   L++    R G ++ L +P +G+P PE+ W K DG   D
Sbjct: 16429 DVPGPIIVEEKLEAPDIDLDLELRKIINIRAGGSLRLFVPIKGRPTPEVKWGKVDGEIRD 16488

Query: 889   KNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIE 948
                I++ +S T  +  +    R  SGKY L ++     ++A + ++++D P PP  +K+ 
Sbjct: 16489 AAIIDVTSSFTSLV--LDNVNRYDSGKYTLTLENSSGTKSAFVTVRVLDTPSPPVNLKVT 16546

Query: 949   DVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEY 1008
             ++  ++V++TW PP  DG + I  Y ++K +     +  V+ + H+ S  I +L  G  Y
Sbjct: 16547 EITKDSVSITWEPPLLDGGSKIKNYIVEKREATRKSYAAVVTNCHKNSWKIDQLQEGCSY 16606

Query: 1009  YFRVFSENMCGL---SEDATMTKESAVIARDGKI 1039
             YFRV +EN  G+   ++ A   K + V    GKI
Sbjct: 16607 YFRVTAENEYGIGLPAQTADPIKVAEVPQPPGKI 16640



 Score =  222 bits (566), Expect = 1e-57
 Identities = 161/583 (27%), Positives = 256/583 (43%), Gaps = 22/583 (3%)

Query: 455   LKPLKILTPLTDQTVNLGKEICLKCEI--SENIPGKWTKNGLPVQESDRLKVVHKGRIHK 512
             L P KIL P    T+  GK++ ++  +    +   KW K    V  S  L V        
Sbjct: 12400 LLPPKILMP-EQITIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSI 12458

Query: 513   LVIANALTEDEGDYVFAPDAYNVTLPAKVHVI-----DPPKIILDGLDADNTVTVIAGNK 567
             L+I +   +D G Y    +  + T   K+ V+      PP+   D  D D          
Sbjct: 12459 LIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPGPPQPPFDISDIDADAC-----S 12513

Query: 568   LRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLK 627
             L   IP+         +      +  G       S   +S  V  +    +  ++ +  +
Sbjct: 12514 LSWHIPLEDGGSNITNYIVEKCDVSRGDWVTALASVTKTSCRVGKLIPGQEY-IFRVRAE 12572

Query: 628   NEAGEAHASIKVKVV-----DFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIE 682
             N  G +      K+V       P  P    VT+V  D   + W+ P  DGGSPI+GY IE
Sbjct: 12573 NRFGISEPLTSPKMVAQFPFGVPSEPKNARVTKVNKDCIFVAWDRPDSDGGSPIIGYLIE 12632

Query: 683   RKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAV 742
             RK++ S  W++ N  L + T +    ++EG+ Y  RI+A+N  G S PS P+        
Sbjct: 12633 RKERNSLLWVKANDTLVRSTEYPCAGLVEGLEYSFRIYALNKAGSSPPSKPTEYVTARMP 12692

Query: 743   TSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVAN--KDLIDKT 800
               PP    V  VT +TV++ W  P H G + + GY +E C    + W+  N     I + 
Sbjct: 12693 VDPPGKPEVIDVTKSTVSLIWARPKHDGGSKIIGYFVEACKLPGDKWVRCNTAPHQIPQE 12752

Query: 801   KFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRV 860
             ++T TGL   A+   R  A  A   S P   S P+ +     PP+I +   +K     + 
Sbjct: 12753 EYTATGLEEKAQYQFRAIARTAVNISPPSEPSDPVTILAENVPPRIDLSVAMKSLLTVKA 12812

Query: 861   GEAVNLVIPFQGKPRPELTWKKDGAEIDKNQ-INIRNSETDTIIFIRKAERSHSGKYDLQ 919
             G  V L     GKP P ++WKKDG  +   + I +        + +    R  SG Y + 
Sbjct: 12813 GTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTIT 12872

Query: 920   VKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKAD 979
              +     ++A+I ++++D+PGPP  VKI  ++ +   L+W PP +DG + IT Y + K +
Sbjct: 12873 AENSSGSKSATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYIVDKRE 12932

Query: 980   KKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSE 1022
                  W  V      TS ++ +L+ G+EY FR+ +EN  G+ +
Sbjct: 12933 TSRPNWAQVSATVPITSCSVEKLIEGHEYQFRICAENKYGVGD 12975



 Score =  222 bits (565), Expect = 2e-57
 Identities = 160/535 (29%), Positives = 257/535 (48%), Gaps = 52/535 (9%)

Query: 527  VFAPDAYNVTLPAKV--HVI--DP---PKIILDGLDADNTVTVIAGNKLRLEIPISGEPP 579
            V A +A  V+ P+++  +V+  DP   P I L+  D    + VI G KL + +P    P 
Sbjct: 7863 VRAVNAIGVSEPSEISENVVAKDPDCKPTIDLETHD----IIVIEGEKLSIPVPFRAVPV 7918

Query: 580  PKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKV 639
            P   W +  K + + S R+  ++   S+ L +  + R D+G+Y I L+N+ G A ASI V
Sbjct: 7919 PTVSWHKDGKEV-KASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATASINV 7977

Query: 640  KVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLC 699
            KV+  P P      +++    C + WEPP +DGG+PIL Y +ER++     ++ +     
Sbjct: 7978 KVIGLPGPCKDIKASDITKSSCKLTWEPPEFDGGTPILHYVLERREAGRRTYIPVMSGEN 8037

Query: 700  KETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFV---PLAVTSPPTLLTVDSVTD 756
            K  ++  K +I    Y  R+ AVN +G  +      P +   P     PP  + V + T 
Sbjct: 8038 K-LSWTVKDLIPNGEYFFRVKAVNKVGGGEYIELKNPVIAQDPKQPPDPPVDVEVHNPTA 8096

Query: 757  TTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVR 816
              +T+ W+PP + G + + GY++E   +G E W   N+ L+    +T  GL    +   R
Sbjct: 8097 EAMTITWKPPLYDGGSKIMGYIIEKIAKGEERWKRCNEHLVPILTYTAKGLEEGKEYQFR 8156

Query: 817  VKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRP 876
            V+A NAAG SEP   + P    + I+ PK+ +   L+   ++R G+ + L     G P P
Sbjct: 8157 VRAENAAGISEPSRATPPTKAVDPIDAPKVILRTSLE---VKR-GDEIALDASISGSPYP 8212

Query: 877  ELTWKKD-----GAEIDK------------------------NQINIRNSET-DTIIFIR 906
             +TW KD       EI K                         +++I NS+  ++ + +R
Sbjct: 8213 TITWIKDENVIVPEEIKKRAAPLVRRRKGEVQEEEPFVLPLTQRLSIDNSKKGESQLRVR 8272

Query: 907  KAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDG 966
             + R   G Y ++V+ D  +  A   + ++D PGPP     ED+   +V   W PP DDG
Sbjct: 8273 DSLRPDHGLYMIKVENDHGIAKAPCTVSVLDTPGPPINFVFEDIRKTSVLCKWEPPLDDG 8332

Query: 967  NAAITGYTIQKAD--KKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCG 1019
             + I  YT++K D  K   EW  V         ++T+L+ G EY FRV +EN  G
Sbjct: 8333 GSEIINYTLEKKDKTKPDSEWIVVTSTLRHCKYSVTKLIEGKEYLFRVRAENRFG 8387



 Score =  220 bits (561), Expect = 5e-57
 Identities = 176/654 (26%), Positives = 292/654 (44%), Gaps = 63/654 (9%)

Query: 405   EIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPL 464
             +++ G K  +RIR +         GA  A +     +    +  A       P  +L P 
Sbjct: 13840 DLVEGGKYEFRIRAKNTA------GAISAPSESTETIICKDEYEA-------PTIVLDPT 13886

Query: 465   TDQ--TVNLGKEICLKCE--ISENIP-GKWTKNGLPVQESDRLKVVHKGRIHKLVIANAL 519
                  T+  G  I L     + + +P   W+K G  ++ SD  ++        L I  A 
Sbjct: 13887 IKDGLTIKAGDTIVLNAISILGKPLPKSSWSKAGKDIRPSDITQITSTPTSSMLTIKYAT 13946

Query: 520   TEDEGDY-VFAPDAYNVTLP-AKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGE 577
              +D G+Y + A + +   +   KV V+D P     G      ++ ++  K  L    +  
Sbjct: 13947 RKDAGEYTITATNPFGTKVEHVKVTVLDVP-----GPPGPVEISNVSAEKATL----TWT 13997

Query: 578   PPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLK----NE---- 629
             PP +   S     I+E           ++S L+  +   D     H+  K    NE    
Sbjct: 13998 PPLEDGGSPIKSYILEKR---------ETSRLLWTVVSEDIQSCRHVATKLIQGNEYIFR 14048

Query: 630   --------AGEAHASIKVKVVDF---PDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILG 678
                      GE   S  VK+VD    P PP  P V+ V  +   ++W+ P  DGGS I G
Sbjct: 14049 VSAVNHYGKGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTATVSWKRPVDDGGSEITG 14108

Query: 679   YFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFV 738
             Y +ER++K+S RW+R       +   +   + EG  YE R+ A N  GI  PS  S   +
Sbjct: 14109 YHVERREKKSLRWVRAIKTPVSDLRCKVTGLQEGSTYEFRVSAENRAGIGPPSEASDSVL 14168

Query: 739   PLAVTSPPTLLTVDSVTDTT---VTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIV-ANK 794
                   PP   +   VTDTT    ++ W  P + G   + GYV+E+   G E WI     
Sbjct: 14169 MKDAAYPPGPPSNPHVTDTTKKSASLAWGKPHYDGGLEITGYVVEHQKVGDEAWIKDTTG 14228

Query: 795   DLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQ 854
               +  T+F +  L T  K   R+ A+N AG  EP       +V+  + P    +   L++
Sbjct: 14229 TALRITQFVVPDLQTKEKYNFRISAINDAGVGEPAVIPDVEIVEREMAPD-FELDAELRR 14287

Query: 855   TYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSG 914
             T + R G ++ + +P +G+P PE+TW KD   + KN+ NI N+E+ T++ I +  R  +G
Sbjct: 14288 TLVVRAGLSIRIFVPIKGRPAPEVTWTKDNINL-KNRANIENTESFTLLIIPECNRYDTG 14346

Query: 915   KYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYT 974
             K+ + ++     ++  ++++++D PGP   ++  D+  ++V L W  P  DG + IT Y 
Sbjct: 14347 KFVMTIENPAGKKSGFVNVRVLDTPGPVLNLRPTDITKDSVTLHWDLPLIDGGSRITNYI 14406

Query: 975   IQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTK 1028
             ++K +     + T     H+ +  +T L  G EY+FRV +EN  G+ E    T+
Sbjct: 14407 VEKREATRKSYSTATTKCHKCTYKVTGLSEGCEYFFRVMAENEYGIGEPTETTE 14460



 Score =  218 bits (554), Expect = 3e-56
 Identities = 159/598 (26%), Positives = 266/598 (44%), Gaps = 55/598 (9%)

Query: 459   KILTPLTDQTVNLGKEICLKCEISENIPG----------KWTKNGLPVQESDRLKVVHKG 508
             K++ P  +  V L + + +K   +   P           KWT +G  ++  +   V    
Sbjct: 11007 KLVPPSVELDVKLIEGLVVKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDN 11066

Query: 509   RIHKLVIANALTEDEGDYVFAPD--AYNVTLPAKVHVID---PPKIILDGLDADNTVTVI 563
                 L I N L  D G+Y       A + T+   + V+D   PP   ++ LD        
Sbjct: 11067 FSSVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTVLDVPGPPTGPINILDVTPE---- 11122

Query: 564   AGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIR-----TESYPDSSTLVIDIAERDD 618
                     + IS +PP     S     I+E     +       S    + L I   ++  
Sbjct: 11123 -------HMTISWQPPKDDGGSPVINYIVEKQDTRKDTWGVVSSGSSKTKLKIPHLQKGC 11175

Query: 619   SGVYHINLKNEAG-----EAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGG 673
               V+ +  +N+ G     ++  ++       P PP  P VT++ ++   ++W  P  DGG
Sbjct: 11176 EYVFRVRAENKIGVGPPLDSTPTVAKHKFSPPSPPGKPVVTDITENAATVSWTLPKSDGG 11235

Query: 674   SPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMP 733
             SPI GY++ER++  + +W+R+N     +  F    + EG  YE R+FA N  G+SKPS  
Sbjct: 11236 SPITGYYMERREV-TGKWVRVNKTPIADLKFRVTGLYEGNTYEFRVFAENLAGLSKPSPS 11294

Query: 734   SRPFV---PLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWI 790
             S P     P+    PP    +   +  T  + W  P   G + + GYV+E    GT  W 
Sbjct: 11295 SDPIKACRPIKPPGPPINPKLKDKSRETADLVWTKPLSDGGSPILGYVVECQKPGTAQWN 11354

Query: 791   VANKD-LIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIP 849
               NKD LI +  F + GL    +   R+KA N  G  EP+  ++ ++ K+I+ PP++ + 
Sbjct: 11355 RINKDELIRQCAFRVPGLIEGNEYRFRIKAANIVGEGEPRELAESVIAKDILHPPEVELD 11414

Query: 850   RHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTI------- 902
                +     RVG+ + ++   +G+P P++TW K+G      ++ +R    D I       
Sbjct: 11415 VTCRDVITVRVGQTIRILARVKGRPEPDITWTKEG------KVLVREKRVDLIQDLPRVE 11468

Query: 903   IFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPP 962
             + I++A R+  GKY +  K        S  + ++DRPGP Q +K+ +V  EN  ++W  P
Sbjct: 11469 LQIKEAVRADHGKYIISAKNSSGHAQGSAIVNVLDRPGPCQNLKVTNVTKENCTISWENP 11528

Query: 963   KDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGL 1020
              D+G + IT + ++        W  V     +       L+  NEYYFRV +EN  G+
Sbjct: 11529 LDNGGSEITNFIVEYRKPNQKGWSIVASDVTKRLIK-ANLLANNEYYFRVCAENKVGV 11585



 Score =  214 bits (544), Expect = 5e-55
 Identities = 128/407 (31%), Positives = 204/407 (50%), Gaps = 22/407 (5%)

Query: 636  SIKVKVVD---FPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWM 692
            S KV + D    P PP  P V        +++W PP  +GGSPI GY++E++++ S  W 
Sbjct: 9090 SDKVVIQDPYRLPGPPGKPKVLARTKGSMLVSWTPPLDNGGSPITGYWLEKREEGSPYWS 9149

Query: 693  RLNFDLC-----KETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFV---PLAVTS 744
            R++         K   F   +++EGV Y+ R  A+NA GI  PS PS P V   P+    
Sbjct: 9150 RVSRAPITKVGLKGVEFNVPRLLEGVKYQFRAMAINAAGIGPPSEPSDPEVAGDPIFPPG 9209

Query: 745  PPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKD--LIDKTKF 802
            PP+   V   T +++++ W+PP   G + + GY++E   EGT DW   N+   LI   + 
Sbjct: 9210 PPSCPEVKDKTKSSISLGWKPPAKDGGSPIKGYIVEMQEEGTTDWKRVNEPDKLITTCEC 9269

Query: 803  TITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGE 862
             +  L    K   RVKAVN AG SEP   +  I   +I E P++ I    +   + + G 
Sbjct: 9270 VVPNLKELRKYRFRVKAVNEAGESEPSDTTGEIPATDIQEEPEVFIDIGAQDCLVCKAGS 9329

Query: 863  AVNLVIPFQGKPRPELTWK---------KDGAEIDKNQINIRNSETDTIIFIRKAERSHS 913
             + +    +G+P P+ +W+         KDG         +  +E  ++I I + +RSH+
Sbjct: 9330 QIRIPAVIKGRPTPKSSWEFDGKAKKAMKDGVHDIPEDAQLETAENSSVIIIPECKRSHT 9389

Query: 914  GKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGY 973
            GKY +  K     +TA+  ++++D PGPP+ +K+ D+   +  L+W  P DDG   I GY
Sbjct: 9390 GKYSITAKNKAGQKTANCRVKVMDVPGPPKDLKVSDITRGSCRLSWKMPDDDGGDRIKGY 9449

Query: 974  TIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGL 1020
             I+K       W  V      T+  + +L+   +Y+FRV +EN  G+
Sbjct: 9450 VIEKRTIDGKAWTKVNPDCGSTTFVVPDLLSEQQYFFRVRAENRFGI 9496



 Score =  214 bits (544), Expect = 5e-55
 Identities = 163/595 (27%), Positives = 269/595 (45%), Gaps = 44/595 (7%)

Query: 468   TVNLGKEICLKCEISENIPGK--WTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGD 525
             T+  G ++ L   +      K  WTK    +   +++ + + G+    VI      D G 
Sbjct: 22561 TIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSGK 22620

Query: 526   YVFAPDAYNVT--LPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPP---- 579
             Y       + T  +   V V+D P     G     TV+ +   K  L   +  E      
Sbjct: 22621 YTLTVKNASGTKAVSVMVKVLDSP-----GPCGKLTVSRVTQEKCTLAWSLPQEDGGAEI 22675

Query: 580   -----PKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAG--- 631
                   +   SR +  I+EG     T SY      V+    +++  ++ +   N+ G   
Sbjct: 22676 THYIVERRETSRLNWVIVEGE--CPTLSY------VVTRLIKNNEYIFRVRAVNKYGPGV 22727

Query: 632   --EAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSS 689
               E+   +       P PP  P     G +  I+ W  P  DGG+ I  Y +++++K+S 
Sbjct: 22728 PVESEPIVARNSFTIPSPPGIPEEVGTGKEHIIIQWTKPESDGGNEISNYLVDKREKKSL 22787

Query: 690   RWMRLNFD-LCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFV----PLAVTS 744
             RW R+N D +  +T  +   ++EG  Y+ R+ AVNA G S+PS  S  F+    P     
Sbjct: 22788 RWTRVNKDYVVYDTRLKVTSLMEGCDYQFRVTAVNAAGNSEPSEASN-FISCREPSYTPG 22846

Query: 745   PPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWI-VANKDLIDKTKFT 803
             PP+   V   T  ++++ W  P + G   + GYVLE   + T+ W  V     I  T+FT
Sbjct: 22847 PPSAPRVVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDTDQWYRVHTNATIRNTEFT 22906

Query: 804   ITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEA 863
             +  L    K   RV AVN  G SE       I   E IE P + +   LK+T   R G +
Sbjct: 22907 VPDLKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEIPDLELADDLKKTVTIRAGAS 22966

Query: 864   VNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVD 923
             + L++   G+P P +TW K G ++    I I  +E+ +++ + K  R  +GKY ++ +  
Sbjct: 22967 LRLMVSVSGRPPPVITWSKQGIDLASRAI-IDTTESYSLLIVDKVNRYDAGKYTIEAENQ 23025

Query: 924   KFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSM 983
                ++A++ +++ D PGP   VK+++V  ++V +TW  P  DG A +  Y ++K +    
Sbjct: 23026 SGKKSATVLVKVYDTPGPCPSVKVKEVSRDSVTITWEIPTIDGGAPVNNYIVEKREAAMR 23085

Query: 984   EWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSE-----DATMTKESAVI 1033
              + TV     +T   I+ LV G  YYFRV  EN+ G+ E     DA +  E  ++
Sbjct: 23086 AFKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYGIGEPCETSDAVLVSEVPLV 23140



 Score =  213 bits (543), Expect = 6e-55
 Identities = 156/581 (26%), Positives = 275/581 (47%), Gaps = 32/581 (5%)

Query: 469   VNLGKEICLKCEI-SENIPGK-WTKNGLPVQESD-RLKVVHKGRIHKLVIANALTEDEGD 525
             V+ G+   L+ +I  + IP   W+K+G  ++E+  R+++    +   LV+ + +  D G 
Sbjct: 18222 VHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQ 18281

Query: 526   YVFAPDAYNVT--LPAKVHVIDPP-----KIILDGLDAD------NTVTVIAGNKLRLEI 572
             Y+        T  +P  V V+D P      + + G+ A+      N      G  +   I
Sbjct: 18282 YILKLSNVGGTKSIPITVKVLDRPGPPEGPLKVTGVTAEKCYLAWNPPLQDGGANISHYI 18341

Query: 573   PISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGE 632
              I      +  W++    +   + ++ T+  P +  +   +A       Y I    E+G 
Sbjct: 18342 -IEKRETSRLSWTQVSTEVQALNYKV-TKLLPGNEYIFRVMAVNK----YGIGEPLESGP 18395

Query: 633   AHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWM 692
               A    K    P PP  P V+ +  D  ++ W  P  DGG+ I GY +E++ K+  RW 
Sbjct: 18396 VTACNPYKP---PGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILEKRDKEGVRWT 18452

Query: 693   RLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVD 752
             + N     +       + EG +YE R+ A NA G+ +PS PS  +       PP   +  
Sbjct: 18453 KCNKKTLTDLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRACDALYPPGPPSNP 18512

Query: 753   SVTDT---TVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDL-IDKTKFTITGLP 808
              VTDT   +V++ W  P + G A + GYV+E      ++W        +   +FT+T L 
Sbjct: 18513 KVTDTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAADEWTTCTPPTGLQGKQFTVTKLK 18572

Query: 809   TDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVI 868
              + +   R+ A+N+ G  EP      ++ +E IEPP+I +   L++  + R    + L +
Sbjct: 18573 ENTEYNFRICAINSEGVGEPATLPGSVVAQERIEPPEIELDADLRKVVVLRASATLRLFV 18632

Query: 869   PFQGKPRPELTWKK-DGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVE 927
               +G+P PE+ W+K +G   D+ QI + +S   T++ I    R  SG+Y+L ++ +   +
Sbjct: 18633 TIKGRPEPEVKWEKAEGILTDRAQIEVTSS--FTMLVIDNVTRFDSGRYNLTLENNSGSK 18690

Query: 928   TASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFT 987
             TA ++++++D P  P  + I +V  ++V L+W PP  DG A IT Y ++K +     + T
Sbjct: 18691 TAFVNVRVLDSPSAPVNLTIREVKKDSVTLSWEPPLIDGGAKITNYIVEKRETTRKAYAT 18750

Query: 988   VIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTK 1028
             +  +  +T+  I  L  G  YYFRV + N  G+   A  T+
Sbjct: 18751 ITNNCTKTTFRIENLQEGCSYYFRVLASNEYGIGLPAETTE 18791



 Score =  213 bits (542), Expect = 8e-55
 Identities = 117/390 (30%), Positives = 208/390 (53%), Gaps = 6/390 (1%)

Query: 645   PDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTF 704
             P PP  P VT++  +   + W  P  DGGS I GYF+E++ K+S  W ++  +  ++T  
Sbjct: 20569 PGPPGIPEVTKITKNSMTVVWSRPIADGGSDISGYFLEKRDKKSLGWFKVLKETIRDTRQ 20628

Query: 705   EPKKMIEGVAYEVRIFAVNAIG---ISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTM 761
             +   + E   Y+ R+ AVNA G    S+PS   +   P+    PP  + +   T +++T+
Sbjct: 20629 KVTGLTENSDYQYRVCAVNAAGQGPFSEPSEFYKAADPIDPPGPPAKIRIADSTKSSITL 20688

Query: 762   RWRPPDHIGAAGLDGYVLEYCFEGTEDWI-VANKDLIDKTKFTITGLPTDAKIFVRVKAV 820
              W  P + G + + GYV+E      E+W  V+ K  +  T++ ++ L      + RV AV
Sbjct: 20689 GWSKPVYDGGSAVTGYVVEIRQGEEEEWTTVSTKGEVRTTEYVVSNLKPGVNYYFRVSAV 20748

Query: 821   NAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTW 880
             N AG  EP   ++P+  K+I+E P+I +   L+ + I + GE V ++IPF+G+P P +TW
Sbjct: 20749 NCAGQGEPIEMNEPVQAKDILEAPEIDLDVALRTSVIAKAGEDVQVLIPFKGRPPPTVTW 20808

Query: 881   KKDGAEIDKN-QINIRNSETDTIIFIRKAERSHSGKYDLQVKVD-KFVETASIDIQIIDR 938
             +KD   +  + + +I N+++ +++ I +  R+ +GKY L ++      +++++ ++++D 
Sbjct: 20809 RKDEKNLGSDARYSIENTDSSSLLTIPQVTRNDTGKYILTIENGVGEPKSSTVSVKVLDT 20868

Query: 939   PGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSAT 998
             P   Q ++++ V    V L W PP  DG + I  Y I+K D     W  V      TS  
Sbjct: 20869 PAACQKLQVKHVSRGTVTLLWDPPLIDGGSPIINYVIEKRDATKRTWSVVSHKCSSTSFK 20928

Query: 999   ITELVIGNEYYFRVFSENMCGLSEDATMTK 1028
             + +L     ++FRV +EN  G+ E    T+
Sbjct: 20929 LIDLSEKTPFFFRVLAENEIGIGEPCETTE 20958



 Score =  210 bits (535), Expect = 5e-54
 Identities = 144/504 (28%), Positives = 232/504 (46%), Gaps = 21/504 (4%)

Query: 545  DPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYP 604
            +PP + LD +     + ++AG  LR+   ++G P P  +W++ +  +     R+  ++  
Sbjct: 8603 EPPAVELD-VSVKGGIQIMAGKTLRIPAVVTGRPVPTKVWTKEEGEL--DKDRVVIDNVG 8659

Query: 605  DSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMN 664
              S L+I  A R D G Y I   N  G   A+ +V+V D P P +           C++N
Sbjct: 8660 TKSELIIKDALRKDHGRYVITATNSCGSKFAAARVEVFDVPGPVLDLKPVVTNRKMCLLN 8719

Query: 665  WEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNA 724
            W  P  DGGS I G+ IERK  +   W R   +  + +  +   ++EG  Y+ R+ A N 
Sbjct: 8720 WSDPEDDGGSEITGFIIERKDAKMHTW-RQPIE-TERSKCDITGLLEGQEYKFRVIAKNK 8777

Query: 725  IGISKPSM--PSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYC 782
             G   P    P     PL   + P  LT    T +T+T+ W+ P   G + + GY++E  
Sbjct: 8778 FGCGPPVEIGPILAVDPLGPPTSPERLTYTERTKSTITLDWKEPRSNGGSPIQGYIIEKR 8837

Query: 783  FEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIE 842
                 D+   NK L   T F +  L        RVKAVN  G SEP      +++++   
Sbjct: 8838 RHDKPDFERVNKRLCPTTSFLVENLDEHQMYEFRVKAVNEIGESEPS-LPLNVVIQDDEV 8896

Query: 843  PPKIRIPRHLKQTYIR-RVGEAVNLVIPFQGKPRPELTWKKDGAEIDK-------NQINI 894
            PP I++   ++   I+ + GE V++     G P P++ W K+   I+K        +  +
Sbjct: 8897 PPTIKLRLSVRGDTIKVKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEV 8956

Query: 895  RNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGEN 954
              SE  T + I KA R   G Y +           ++ +++ DRP PP+ + + D+  E+
Sbjct: 8957 SRSEAKTELSIPKAVREDKGTYTVTASNRLGSVFRNVHVEVYDRPSPPRNLAVTDIKAES 9016

Query: 955  VALTWTPPKDDGNAAITGYTIQKAD--KKSMEWFTVIEHYHRTSATITELVIGNEYYFRV 1012
              LTW  P D+G + IT Y I K D  +K  EW  V          I +L+   +Y FRV
Sbjct: 9017 CYLTWDAPLDNGGSEITHYVIDKRDASRKKAEWEEVTNTAVEKRYGIWKLIPNGQYEFRV 9076

Query: 1013 FSENMCGLSEDATMTKESAVIARD 1036
             + N  G+S++    K   V+ +D
Sbjct: 9077 RAVNKYGISDEC---KSDKVVIQD 9097



 Score =  209 bits (533), Expect = 9e-54
 Identities = 155/595 (26%), Positives = 276/595 (46%), Gaps = 28/595 (4%)

Query: 445   GQSSAKLSVDLKPLKILTPLTDQ-TVNLGKEICLKCEI-SENIPG-KWTKNGLPVQESDR 501
             G  +AK  V+L  + +     D   VN G+   L+ ++  + +P  +W +    ++ES R
Sbjct: 17115 GPITAKDEVELPRISMDPKFRDTIVVNAGETFRLEADVHGKPLPTIEWLRGDKEIEESAR 17174

Query: 502   LKVVHKGRIHKLVIANALTEDEGDYVFAPD--AYNVTLPAKVHVIDPPKIILDGLDADNT 559
              ++ +      L++ +A+  D G Y+      A + + P  V V+D P       +    
Sbjct: 17175 CEIKNTDFKALLIVKDAIRIDGGQYILRASNVAGSKSFPVNVKVLDRP----GPPEGPVQ 17230

Query: 560   VTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIR-----TESYPDSSTLVIDIA 614
             VT +   K  L    +  PP +   S     ++E     R       S   +++L +   
Sbjct: 17231 VTGVTSEKCSL----TWSPPLQDGGSDISHYVVEKRETSRLAWTVVASEVVTNSLKVTKL 17286

Query: 615   ERDDSGVYHINLKNE--AGEAHASIKVKVVD---FPDPPVAPTVTEVGDDWCIMNWEPPA 669
                +  V+ I   N+   GE   S  V + +    P PP +  VT +  D   + W  P 
Sbjct: 17287 LEGNEYVFRIMAVNKYGVGEPLESAPVLMKNPFVLPGPPKSLEVTNIAKDSMTVCWNRPD 17346

Query: 670   YDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISK 729
              DGGS I+GY +E++ +   RW++ N     +       + E   YE R+ A NA G+ +
Sbjct: 17347 SDGGSEIIGYIVEKRDRSGIRWIKCNKRRITDLRLRVTGLTEDHEYEFRVSAENAAGVGE 17406

Query: 730   PSMPS---RPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGT 786
             PS  +   +   P+    PPT   +   T  ++T+ W  P + G + + GYV+E C    
Sbjct: 17407 PSPATVYYKACDPVFKPGPPTNAHIVDTTKNSITLAWGKPIYDGGSEILGYVVEICKADE 17466

Query: 787   EDW-IVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPK 845
             E+W IV  +  +  T+F I+ L    +  +RV A+N  G  E       +  ++ +E P+
Sbjct: 17467 EEWQIVTPQTGLRVTRFEISKLTEHQEYKIRVCALNKVGLGEATSVPGTVKPEDKLEAPE 17526

Query: 846   IRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFI 905
             + +   L++  + R G +  + IPF+G+P PE+TW ++  E   +++ I      T + I
Sbjct: 17527 LDLDSELRKGIVVRAGGSARIHIPFKGRPTPEITWSREEGEFT-DKVQIEKGVNYTQLSI 17585

Query: 906   RKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDD 965
                +R+ +GKY L+++     ++A + ++++D PGPPQ + +++V  ++  L W PP  D
Sbjct: 17586 DNCDRNDAGKYILKLENSSGSKSAFVTVKVLDTPGPPQNLAVKEVRKDSAFLVWEPPIID 17645

Query: 966   GNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGL 1020
             G A +  Y I K +     +  V     +TS  +  L  G  YYFRV +EN  G+
Sbjct: 17646 GGAKVKNYVIDKRESTRKAYANVSSKCSKTSFKVENLTEGAIYYFRVMAENEFGV 17700



 Score =  207 bits (528), Expect = 4e-53
 Identities = 124/404 (30%), Positives = 206/404 (50%), Gaps = 10/404 (2%)

Query: 645  PDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTF 704
            P PP A  V +V      + WEPP  DGG PI  Y IE+K++  +RW++       +  F
Sbjct: 7687 PGPPYALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKERLGTRWVKAGKTAGPDCNF 7746

Query: 705  EPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFV---PLAVTSPPTLLTVDSVTDTTVTM 761
                +IEG   + ++ A N  G+  PS P+       P +  SPP  L V       + +
Sbjct: 7747 RVTDVIEGTEVQFQVRAENEAGVGHPSEPTEILSIEDPTSPPSPPLDLHVTDAGRKHIAI 7806

Query: 762  RWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTIT-GLPTDAKIFVRVKAV 820
             W+PP+  G + + GY +E C  GTE W+  N   I   KF +  G+  D +  +RV+AV
Sbjct: 7807 AWKPPEKNGGSPIIGYHVEMCPVGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYVLRVRAV 7866

Query: 821  NAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTW 880
            NA G SEP   S+ ++ K+    P I +  H     I   GE +++ +PF+  P P ++W
Sbjct: 7867 NAIGVSEPSEISENVVAKDPDCKPTIDLETH---DIIVIEGEKLSIPVPFRAVPVPTVSW 7923

Query: 881  KKDGAEID-KNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRP 939
             KDG E+   +++ ++N      + + K+ R+ +G Y + ++      TASI++++I  P
Sbjct: 7924 HKDGKEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSATASINVKVIGLP 7983

Query: 940  GPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATI 999
            GP + +K  D+   +  LTW PP+ DG   I  Y +++ +     +  V+   ++ S T+
Sbjct: 7984 GPCKDIKASDITKSSCKLTWEPPEFDGGTPILHYVLERREAGRRTYIPVMSGENKLSWTV 8043

Query: 1000 TELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNP 1043
             +L+   EY+FRV + N  G  E   +  ++ VIA+D K   +P
Sbjct: 8044 KDLIPNGEYFFRVKAVNKVGGGEYIEL--KNPVIAQDPKQPPDP 8085



 Score =  205 bits (522), Expect = 2e-52
 Identities = 140/501 (27%), Positives = 228/501 (45%), Gaps = 20/501 (3%)

Query: 543   VIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTES 602
             ++ PP++ LD +   + +TV  G  +R+   + G P P   W++  K ++      R + 
Sbjct: 11405 ILHPPEVELD-VTCRDVITVRVGQTIRILARVKGRPEPDITWTKEGKVLVREK---RVDL 11460

Query: 603   YPDSSTLVIDIAE--RDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDW 660
               D   + + I E  R D G Y I+ KN +G A  S  V V+D P P     VT V  + 
Sbjct: 11461 IQDLPRVELQIKEAVRADHGKYIISAKNSSGHAQGSAIVNVLDRPGPCQNLKVTNVTKEN 11520

Query: 661   CIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIF 720
             C ++WE P  +GGS I  + +E +K     W  +  D+ K        ++    Y  R+ 
Sbjct: 11521 CTISWENPLDNGGSEITNFIVEYRKPNQKGWSIVASDVTKRLI--KANLLANNEYYFRVC 11578

Query: 721   AVNAIGISKPSMPSRPFV---PLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGY 777
             A N +G+        P +   P+     P  L +     T V ++WR PD+ G +    Y
Sbjct: 11579 AENKVGVGPTIETKTPILAINPIDRPGEPENLHIADKGKTFVYLKWRRPDYDGGSPNLSY 11638

Query: 778   VLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILV 837
              +E   +G++DW   +K  I +T + +     +     RV+  N  G S+    ++ ++V
Sbjct: 11639 HVERRLKGSDDWERVHKGSIKETHYMVDRCVENQIYEFRVQTKNEGGESD-WVKTEEVVV 11697

Query: 838   KEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQ---INI 894
             KE ++ P + +   L      + G+ + L    +GKP PE+ W KD    D  +   + I
Sbjct: 11698 KEDLQKPVLDLK--LSGVLTVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKI 11755

Query: 895   RNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGEN 954
                   +   + KA+RS  GKY +          A   + ++D+PGP + +KI DV  + 
Sbjct: 11756 DTRADSSKFSLTKAKRSDGGKYVVTATNTAGSFVAYATVNVLDKPGPVRNLKIVDVSSDR 11815

Query: 955   VALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFS 1014
               + W PP+DDG   I  Y ++K + K M W T          T+T L+ GNEY FRV +
Sbjct: 11816 CTVCWDPPEDDGGCEIQNYILEKCETKRMVWSTYSATVLTPGTTVTRLIEGNEYIFRVRA 11875

Query: 1015  ENMCGLSEDATMTKESAVIAR 1035
             EN  G       T+   VIA+
Sbjct: 11876 ENKIGTGPP---TESKPVIAK 11893



 Score =  204 bits (520), Expect = 3e-52
 Identities = 148/557 (26%), Positives = 258/557 (46%), Gaps = 31/557 (5%)

Query: 489   WTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAK----VHVI 544
             W K+G+ +++   +++        L + +A  +  G  V+  +A N +  AK    V V 
Sbjct: 21495 WFKDGVEIEKRMNMEITDVLGSTSLFVRDATRDHRG--VYTVEAKNASGSAKAEIKVKVQ 21552

Query: 545   DPPKIILDGLDADNTVTVIAGNKLRL--EIPISGEPPP-------KAMWSRGDKAIMEGS 595
             D P  ++  +   N    I G K+ L  + P++    P       K   SR   A++E  
Sbjct: 21553 DTPGKVVGPIRFTN----ITGEKMTLWWDAPLNDGCAPITHYIIEKRETSRLAWALIED- 21607

Query: 596   GRIRTESYPDSSTLVIDIAERDDSGV--YHINLKNEAGEAHASIKVKVVDFPDPPVAPTV 653
              +   +SY     +  +  +   S V  + +    ++    A I+  V   PD P  P  
Sbjct: 21608 -KCEAQSYTAIKLINGNEYQFRVSAVNKFGVGRPLDSDPVVAQIQYTV---PDAPGIPEP 21663

Query: 654   TEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMR-LNFDLCKETTFEPKKMIEG 712
             + +  +   + W  P  DGGS I  Y +ER++K+S+RW++ ++     ET F+   + EG
Sbjct: 21664 SNITGNSITLTWARPESDGGSEIQQYILERREKKSTRWVKVISKRPISETRFKVTGLTEG 21723

Query: 713   VAYEVRIFAVNAIGISKPSMPSRPFV---PLAVTSPPTLLTVDSVTDTTVTMRWRPPDHI 769
               YE  + A NA G+   S  SR      P+    PPT++ V   + TTV++ W  P   
Sbjct: 21724 NEYEFHVMAENAAGVGPASGISRLIKCREPVNPPGPPTVVKVTDTSKTTVSLEWSKPVFD 21783

Query: 770   GAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPK 829
             G   + GY++E C     DW   N +   KT++T+T L    +   RV A+N AG  +  
Sbjct: 21784 GGMEIIGYIIEMCKADLGDWHKVNAEACVKTRYTVTDLQAGEEYKFRVSAINGAGKGDSC 21843

Query: 830   YYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDK 889
               +  I   + +  P++ I  + KQT++ R G ++ L I +QG+P P   W K  + +  
Sbjct: 21844 EVTGTIKAVDRLTAPELDIDANFKQTHVVRAGASIRLFIAYQGRPTPTAVWSKPDSNLSL 21903

Query: 890   NQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIED 949
              + +I  +++ + + +    R+ +GKY L V+ +   ++ +  ++++D PGPP  +  +D
Sbjct: 21904 -RADIHTTDSFSTLTVENCNRNDAGKYTLTVENNSGSKSITFTVKVLDTPGPPGPITFKD 21962

Query: 950   VWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYY 1009
             V   +  L W  P  DG A I  Y ++K +     W  + E   R    + +L  G  YY
Sbjct: 21963 VTRGSATLMWDAPLLDGGARIHHYVVEKREASRRSWQVISEKCTRQIFKVNDLAEGVPYY 22022

Query: 1010  FRVFSENMCGLSEDATM 1026
             FRV + N  G+ E   M
Sbjct: 22023 FRVSAVNEYGVGEPYEM 22039



 Score =  203 bits (517), Expect = 7e-52
 Identities = 137/482 (28%), Positives = 227/482 (47%), Gaps = 20/482 (4%)

Query: 645   PDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTF 704
             P  P  P V  V  +   + WE P +DGGS I+GY++E+K++ +  W++ N   C E  +
Sbjct: 22344 PSAPTRPEVYHVSANAMSIRWEEPYHDGGSKIIGYWVEKKERNTILWVKENKVPCLECNY 22403

Query: 705   EPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWR 764
             +   ++EG+ Y+ R +A+NA G+SK S  SRP +       P    V  VT +TV++ W 
Sbjct: 22404 KVTGLVEGLEYQFRTYALNAAGVSKASEASRPIMAQNPVDAPGRPEVTDVTRSTVSLIWS 22463

Query: 765   PPDHIGAAGLDGYVLE---YCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVN 821
              P + G + + GY++E       G   W+  N  ++    FT+T L        RV A N
Sbjct: 22464 APAYDGGSKVVGYIIERKPVSEVGDGRWLKCNYTIVSDNFFTVTALSEGDTYEFRVLAKN 22523

Query: 822   AAGA-SEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIR-RVGEAVNLVIPFQGKPRPELT 879
             AAG  S+    + P+  ++   PPK  +   L    +  R G  + L     GKP P++ 
Sbjct: 22524 AAGVISKGSESTGPVTCRDEYAPPKAELDARLHGDLVTIRAGSDLVLDAAVGGKPEPKII 22583

Query: 880   WKKDGAEIDK-NQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDR 938
             W K   E+D   +++++ +       I+  +RS SGKY L VK     +  S+ ++++D 
Sbjct: 22584 WTKGDKELDLCEKVSLQYTGKRATAVIKFCDRSDSGKYTLTVKNASGTKAVSVMVKVLDS 22643

Query: 939   PGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSAT 998
             PGP   + +  V  E   L W+ P++DG A IT Y +++ +   + W  V       S  
Sbjct: 22644 PGPCGKLTVSRVTQEKCTLAWSLPQEDGGAEITHYIVERRETSRLNWVIVEGECPTLSYV 22703

Query: 999   ITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNP--VYEDFDFSEAPM- 1055
             +T L+  NEY FRV + N  G        +   ++AR+     +P  + E+    +  + 
Sbjct: 22704 VTRLIKNNEYIFRVRAVNKYG---PGVPVESEPIVARNSFTIPSPPGIPEEVGTGKEHII 22760

Query: 1056  --FTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMK-NKVAIVDDPRYRMFSNQGVCTLE 1112
               +T+P  +     G N   N  V    K  + W + NK  +V D R ++ S    C  +
Sbjct: 22761 IQWTKPESD-----GGNEISNYLVDKREKKSLRWTRVNKDYVVYDTRLKVTSLMEGCDYQ 22815

Query: 1113  IR 1114
              R
Sbjct: 22816 FR 22817



 Score =  200 bits (509), Expect = 6e-51
 Identities = 218/906 (24%), Positives = 364/906 (40%), Gaps = 113/906 (12%)

Query: 288  QVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEY 347
            +V +   V F  E+     + KW++N + I  S+KYI   K     L I +  + D + Y
Sbjct: 6153 RVKEQQEVVFNCEVNTEGAKAKWFRNEEAIFDSSKYIILQKDLVYTLRIRDAHLDDQANY 6212

Query: 348  YVTAGDE-----KCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKN 402
             V+  +      K +  L V E  + + + L+D      + V   C+V+  +  +KW KN
Sbjct: 6213 NVSLTNHRGENVKSAANLIVEEEDLRIVEPLKDIETMEKKSVTFWCKVNRLNVTLKWTKN 6272

Query: 403  GEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILT 462
            GEE+    +  YR  V+  KH+L I+     D  EY V     +S A+L +   P + + 
Sbjct: 6273 GEEVPFDNRVSYR--VDKYKHMLTIKDCGFPDEGEYIVTAGQDKSVAELLIIEAPTEFVE 6330

Query: 463  PLTDQTVNLGKEICLKCEIS-ENIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTE 521
             L DQTV    +    C++S E    KW +NG  ++E  + K    G IH+L+I +   +
Sbjct: 6331 HLEDQTVTEFDDAVFSCQLSREKANVKWYRNGREIKEGKKYKFEKDGSIHRLIIKDCRLD 6390

Query: 522  DEGDYVFAPD-----AYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISG 576
            DE +Y    +     A        V +I PP+ IL+   AD  V +   NK ++E+    
Sbjct: 6391 DECEYACGVEDRKSRARLFVEEIPVEIIRPPQDILEAPGAD-VVFLAELNKDKVEV---- 6445

Query: 577  EPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHAS 636
                   W R +  +++G               + DI  RD  G Y    K++  EA A 
Sbjct: 6446 ------QWLRNNMVVVQGDKHQMMSEGKIHRLQICDIKPRDQ-GEYRFIAKDK--EARAK 6496

Query: 637  IKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYF-IERKKKQSSRWMRLN 695
            +++          AP +     D  +        D G P+      +   K  + W + N
Sbjct: 6497 LELAA--------APKIKTADQDLVV--------DVGKPLTMVVPYDAYPKAEAEWFKEN 6540

Query: 696  FDL--------CKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPT 747
              L         ++T+F   +  +G     +I   N  G ++  +  +    + V  P  
Sbjct: 6541 EPLSTKTIDTTAEQTSFRILEAKKGDKGRYKIVLQNKHGKAEGFINLKV---IDVPGPVR 6597

Query: 748  LLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGL 807
             L V    D  V++ W  P   G + + GYV+E      + W++A  D  +  +FT+TGL
Sbjct: 6598 NLEVTETFDGEVSLAWEEPLTDGGSKIIGYVVERRDIKRKTWVLAT-DRAESCEFTVTGL 6656

Query: 808  PTDAKIFV-RVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNL 866
                  ++ RV A N  G  EP     P+  +   + P                G  +N+
Sbjct: 6657 QKGGVEYLFRVSARNRVGTGEPVETDNPVEARSKYDVP----------------GPPLNV 6700

Query: 867  VIPFQGKPRPELTWKKD----GAEIDKNQINIRNSET---DTIIFIRKAERS-------H 912
             I    +    LTW+      GAEI    I +R+  +   DT + +R  + S        
Sbjct: 6701 TITDVNRFGVSLTWEPPEYDGGAEITNYVIELRDKTSIRWDTAMTVRAEDLSATVTDVVE 6760

Query: 913  SGKYDLQVKVDKFV-----ETASIDIQI---IDRPGPPQIVKIEDVWGENVALTWTPPKD 964
              +Y  +V+    +       A+  +++   I+RP PP  +   D    +V L W PP  
Sbjct: 6761 GQEYSFRVRAQNRIGVGKPSAATPFVKVADPIERPSPPVNLTSSDQTQSSVQLKWEPPLK 6820

Query: 965  DGNAAITGYTIQKADKKSMEWFTV-IEHYHRTSATITELVIGNEYYFRVFSENMCGLSED 1023
            DG + I GY I++ ++    W    ++     +  +T L  GN+Y +RV +EN  G+S+ 
Sbjct: 6821 DGGSPILGYIIERCEEGKDNWIRCNMKLVPELTYKVTGLEKGNKYLYRVSAENKAGVSDP 6880

Query: 1024 ATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNA-TLNCSVRGNPK 1082
            + +                P+  D  F E  M      +   +   N  T+     G P+
Sbjct: 6881 SEIL--------------GPLTADDAFVEPTMDLSAFKDGLEVIVPNPITILVPSTGYPR 6926

Query: 1083 PKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLE 1142
            P  TW      +    R +M +      L I      D G Y  K  N + T+  E  ++
Sbjct: 6927 PTATWCFGDKVLETGDRVKMKTLSAYAELVISPSERSDKGIYTLKLENRVKTISGE--ID 6984

Query: 1143 VKVIAQ 1148
            V VIA+
Sbjct: 6985 VNVIAR 6990



 Score =  198 bits (503), Expect = 3e-50
 Identities = 173/674 (25%), Positives = 288/674 (42%), Gaps = 74/674 (10%)

Query: 398  KWFKNGEEIIP-----------GPKSRYRIRVEGKKHILIIEGATKA-------DAAEYS 439
            +W +  E ++P           G + ++R+R E    I     AT         DA +  
Sbjct: 8128 RWKRCNEHLVPILTYTAKGLEEGKEYQFRVRAENAAGISEPSRATPPTKAVDPIDAPKVI 8187

Query: 440  VMTT-----GGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKC---------EISENI 485
            + T+     G + +   S+   P   +T + D+ V + +EI  +          E+ E  
Sbjct: 8188 LRTSLEVKRGDEIALDASISGSPYPTITWIKDENVIVPEEIKKRAAPLVRRRKGEVQEEE 8247

Query: 486  PGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYN--VTLPAKVHV 543
            P       LP+ +   +    KG   +L + ++L  D G Y+   +  +     P  V V
Sbjct: 8248 PFV-----LPLTQRLSIDNSKKGE-SQLRVRDSLRPDHGLYMIKVENDHGIAKAPCTVSV 8301

Query: 544  IDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESY 603
            +D P   ++ +  D   T +             EPP       G   I+  +   + ++ 
Sbjct: 8302 LDTPGPPINFVFEDIRKTSVL---------CKWEPP----LDDGGSEIINYTLEKKDKTK 8348

Query: 604  PDSSTLVIDIAERD-----------DSGVYHINLKNEAGEAHASIKVKVVDF-----PDP 647
            PDS  +V+    R               ++ +  +N  G     +   +V       PD 
Sbjct: 8349 PDSEWIVVTSTLRHCKYSVTKLIEGKEYLFRVRAENRFGPGPPCVSKPLVAKDPFGPPDA 8408

Query: 648  PVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPK 707
            P  P V +V  +  ++ W  P  D GSPILGY++E+++  S+ W R+N  L         
Sbjct: 8409 PDKPIVEDVTSNSMLVKWNEPK-DNGSPILGYWLEKREVNSTHWSRVNKSLLNALKANVD 8467

Query: 708  KMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSP--PTLLTVDSVTDTTVTMRWRP 765
             ++EG+ Y  R+ A NA G  K S PS P       SP  P +  V   + TT+ + W P
Sbjct: 8468 GLLEGLTYVFRVCAENAAGPGKFSPPSDPKTAHDPISPPGPPIPRVTDTSSTTIELEWEP 8527

Query: 766  PDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGA 825
            P   G   + GY ++    GT +W    + +I   ++T+  +   A   +RV AVNAAG 
Sbjct: 8528 PAFNGGGEIVGYFVDKQLVGTNEWSRCTEKMIKVRQYTVKEIREGADYKLRVSAVNAAGE 8587

Query: 826  SEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGA 885
              P   +QP+ V E  EPP + +   +K       G+ + +     G+P P   W K+  
Sbjct: 8588 GPPG-ETQPVTVAEPQEPPAVELDVSVKGGIQIMAGKTLRIPAVVTGRPVPTKVWTKEEG 8646

Query: 886  EIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIV 945
            E+DK+++ I N  T + + I+ A R   G+Y +        + A+  +++ D PGP   +
Sbjct: 8647 ELDKDRVVIDNVGTKSELIIKDALRKDHGRYVITATNSCGSKFAAARVEVFDVPGPVLDL 8706

Query: 946  KIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIG 1005
            K      +   L W+ P+DDG + ITG+ I++ D K   W   IE   R+   IT L+ G
Sbjct: 8707 KPVVTNRKMCLLNWSDPEDDGGSEITGFIIERKDAKMHTWRQPIE-TERSKCDITGLLEG 8765

Query: 1006 NEYYFRVFSENMCG 1019
             EY FRV ++N  G
Sbjct: 8766 QEYKFRVIAKNKFG 8779



 Score =  192 bits (487), Expect = 2e-48
 Identities = 179/703 (25%), Positives = 312/703 (44%), Gaps = 63/703 (8%)

Query: 369   VTKQLEDTTAYCGERVELECE-VSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILII 427
             + K+++D T   GE  +L C+ V     ++KW++ G+E+I   K  Y++  +G+ H L +
Sbjct: 24038 IRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYRFGKELIQSRK--YKMSSDGRTHTLTV 24095

Query: 428   EGATKADAAEYSVMTTGG----QSSAKLSVDLKP-LKILTPLTDQTVN-LGKEICLKCE- 480
                 + D   Y+ + T      ++S+KL +   P      PL ++    +G  + L    
Sbjct: 24096 MTEEQEDEGVYTCIATNEVGEVETSSKLLLQATPQFHPGYPLKEKYYGAVGSTLRLHVMY 24155

Query: 481   ISENIPGK-WTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPA 539
             I   +P   W      +Q S+ + + +      LV+ N   +           Y V L  
Sbjct: 24156 IGRPVPAMTWFHGQKLLQNSENITIENTEHYTHLVMKNVQRKTHAG------KYKVQLSN 24209

Query: 540   KVHVIDPPKIILDGLDADN----TVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIME-- 593
                 +D    ILD    D     T  ++    L+    IS +PP     S     ++E  
Sbjct: 24210 VFGTVDA---ILDVEIQDKPDKPTGPIVIEALLKNSAVISWKPPADDGGSWITNYVVEKC 24266

Query: 594   -----GSGRIRTESYPDSSTLVIDIAERDDSGVY-HINLKNEAG-----EAHASIKVKV- 641
                     ++ + +   ++  ++++ E  ++G Y  ++ +N  G     E  + + +K  
Sbjct: 24267 EAKEGAEWQLVSSAISVTTCRIVNLTE--NAGYYFRVSAQNTFGISDPLEVSSVVIIKSP 24324

Query: 642   VDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKE 701
              + P  P  PT+T V  D C++ W+PPA DGG+ I  Y++E+++K+ ++W+ +  +  +E
Sbjct: 24325 FEKPGAPGKPTITAVTKDSCVVAWKPPASDGGAKIRNYYLEKREKKQNKWISVTTEEIRE 24384

Query: 702   TTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTM 761
             T F  K +IEG+ YE R+   N  G S+ S  S P  P +          + + +  V  
Sbjct: 24385 TVFSVKNLIEGLEYEFRVKCENLGGESEWSEISEPITPKSDVPIQAPHFKEELRNLNVRY 24444

Query: 762   RWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTK-----FTITGLPTDAKIFVR 816
             +          G    ++++  +G E      K  I + K       I  +  D     +
Sbjct: 24445 QSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQLIIASVTDDDATVYQ 24504

Query: 817   VKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRV--GEAVNLVIPFQGKP 874
             V+A N  G+             E+  P KI +P+ L+         GE V++ IPF GKP
Sbjct: 24505 VRATNQGGSVSGT------ASLEVEVPAKIHLPKTLEGMGAVHALRGEVVSIKIPFSGKP 24558

Query: 875   RPELTWKKDGAEIDKN---QINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASI 931
              P +TW+K    ID N   Q+ +  S T +++F    ER  +G Y +  K    ++  ++
Sbjct: 24559 DPVITWQKGQDLIDNNGHYQVIVTRSFT-SLVFPNGVERKDAGFYVVCAKNRFGIDQKTV 24617

Query: 932   DIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEH 991
             ++ + D P PP+ VK+ DV  ++V LTWT P  DG + IT Y ++K    +  W  V   
Sbjct: 24618 ELDVADVPDPPRGVKVSDVSRDSVNLTWTEPASDGGSKITNYIVEKCATTAERWLRV-GQ 24676

Query: 992   YHRTSATITELVIGNEYYFRVFSENMCGLSE-----DATMTKE 1029
                T  T+  L     Y FRV +EN  GLS+     + T+TKE
Sbjct: 24677 ARETRYTVINLFGKTSYQFRVIAENKFGLSKPSEPSEPTITKE 24719



 Score =  181 bits (460), Expect = 3e-45
 Identities = 166/686 (24%), Positives = 284/686 (41%), Gaps = 75/686 (10%)

Query: 375  DTTAYCGERV-ELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKA 433
            D    CGE V E + EV+  +   KW+             YR++   +      +GA+K 
Sbjct: 7135 DKWVACGEPVAETKMEVTGLEEG-KWYA------------YRVKALNR------QGASKP 7175

Query: 434  DAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCEISENIPGK--WTK 491
                  +     Q + ++ +D+K L  LT      V  G +I L   ++     K  WTK
Sbjct: 7176 SRPTEEIQAVDTQEAPEIFLDVKLLAGLT------VKAGTKIELPATVTGKPEPKITWTK 7229

Query: 492  NGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNV----TLPAKVHVIDP- 546
              + +++  R+ + +  +   + I ++   D G Y+   +A NV    T   +V+V+D  
Sbjct: 7230 ADMILKQDKRITIENVPKKSTVTIVDSKRSDTGTYII--EAVNVCGRATAVVEVNVLDKP 7287

Query: 547  -PKIILDGLDADNTVTVIAGNKLR-------LEIPISGEPPPKAMWSRGDKAIMEGSGRI 598
             P    D  D  N   ++  N  R           +        +W +    + + + + 
Sbjct: 7288 GPPAAFDITDVTNESCLLTWNPPRDDGGSKITNYVVERRATDSEVWHKLSSTVKDTNFK- 7346

Query: 599  RTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGD 658
             T+  P+   +    AE     +Y +    +A    A  +    D P PP     +++  
Sbjct: 7347 ATKLIPNKEYIFRVAAE----NMYGVGEPVQASPITAKYQ---FDPPGPPTRLEPSDITK 7399

Query: 659  DWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVR 718
            D   + W  P  DGGSPI GY++ER    + +W+R N    K+TT+  K +     Y  R
Sbjct: 7400 DAVTLTWCEPDDDGGSPITGYWVERLDPDTDKWVRCNKMPVKDTTYRVKGLTNKKKYRFR 7459

Query: 719  IFAVNAIGISKPSMPSRPFV---PLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLD 775
            + A N  G  KPS  + P +   P+    PP   TV  V  T+V + W  P+H G A ++
Sbjct: 7460 VLAENLAGPGKPSKSTEPILIKDPIDPPWPPGKPTVKDVGKTSVRLNWTKPEHDGGAKIE 7519

Query: 776  GYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPI 835
             YV+E    GT++W+   +  +  T+  + GL    +   RV+AVN AG SEP   S P+
Sbjct: 7520 SYVIEMLKTGTDEWVRVAEG-VPTTQHLLPGLMEGQEYSFRVRAVNKAGESEPSEPSDPV 7578

Query: 836  LVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRP------------ELTWKKD 883
            L +E + PP    PR L+   I +    +   +P +    P               W+  
Sbjct: 7579 LCREKLYPPS--PPRWLEVINITKNTADLKWTVPEKDGGSPITNYIVEKRDVRRKGWQTV 7636

Query: 884  GAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQ 943
               +   +  +      ++   R A  +  G+ D        +E + +       PGPP 
Sbjct: 7637 DTTVKDTKCTVTPLTEGSLYVFRVAAENAIGQSDYTE-----IEDSVLAKDTFTTPGPPY 7691

Query: 944  IVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHY-HRTSATITEL 1002
             + + DV   +V L W PPK+DG   I  Y I+K ++    W    +      +  +T++
Sbjct: 7692 ALAVVDVTKRHVDLKWEPPKNDGGRPIQRYVIEKKERLGTRWVKAGKTAGPDCNFRVTDV 7751

Query: 1003 VIGNEYYFRVFSENMCGLSEDATMTK 1028
            + G E  F+V +EN  G+   +  T+
Sbjct: 7752 IEGTEVQFQVRAENEAGVGHPSEPTE 7777



 Score =  162 bits (411), Expect = 1e-39
 Identities = 110/364 (30%), Positives = 175/364 (48%), Gaps = 16/364 (4%)

Query: 289  VDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYY 348
            V  G    F  EL+   + V+WY  G+++ PS K +   +G    L + + ++ D  E  
Sbjct: 5710 VTAGETATFDCELSYEDIPVEWYLKGKKLEPSDKVVPRSEGKVHTLTLRDVKLEDAGEVQ 5769

Query: 349  VTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIP 408
            +TA D K    LFV+EPP+  TK LED T   G    LECEVS ++A VKWFKNG EI+ 
Sbjct: 5770 LTAKDFKTHANLFVKEPPVEFTKPLEDQTVEEGATAVLECEVSRENAKVKWFKNGTEILK 5829

Query: 409  GPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQT 468
              K  Y I  +G+   L+I   T  D   Y+      ++S  L+V    ++ L PLTD  
Sbjct: 5830 SKK--YEIVADGRVRKLVIHDCTPEDIKTYTCDAKDFKTSCNLNVVPPHVEFLRPLTDLQ 5887

Query: 469  VNLGKEICLKCEIS-ENIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYV 527
            V   +    +CE+S EN   KW K+G  +++  +  ++ KG +  LVI   L +DE +Y 
Sbjct: 5888 VREKEMARFECELSRENAKVKWFKDGAEIKKGKKYDIISKGAVRILVINKCLLDDEAEY- 5946

Query: 528  FAPDAYNVTLPAKVHVIDPPKII---LDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMW 584
             + +         + V++   +    L  ++   T T+    KL  E+    +P  + +W
Sbjct: 5947 -SCEVRTARTSGMLTVLEEEAVFTKNLANIEVSETDTI----KLVCEV---SKPGAEVIW 5998

Query: 585  SRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDF 644
             +GD+ I+E +GR    +      LVI  A  +D+G Y+  L +   +    +     +F
Sbjct: 5999 YKGDEEIIE-TGRYEILTEGRKRILVIQNAHLEDAGNYNCRLPSSRTDGKVKVHELAAEF 6057

Query: 645  PDPP 648
               P
Sbjct: 6058 ISKP 6061



 Score =  157 bits (398), Expect = 4e-38
 Identities = 105/308 (34%), Positives = 159/308 (51%), Gaps = 19/308 (6%)

Query: 544   IDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESY 603
             +DPP+I +D    D T+ V AG   +++  I G+P P   W +GD+ +   + R+  +S 
Sbjct: 16041 VDPPRISMDPKYKD-TIVVHAGESFKVDADIYGKPIPTIQWIKGDQEL-SNTARLEIKST 16098

Query: 604   PDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTV-TEVGDDWCI 662
               +++L +  A R DSG Y +  KN AGE   ++ VKV+D P PP  P V + V  + C 
Sbjct: 16099 DFATSLSVKDAVRVDSGNYILKAKNVAGERSVTVNVKVLDRPGPPEGPVVISGVTAEKCT 16158

Query: 663   MNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDL----CKETTFEPKKMIEGVAYEVR 718
             + W+PP  DGGS I+ Y +ER++     W  ++ ++    CK T     K++EG  Y  R
Sbjct: 16159 LAWKPPLQDGGSDIINYIVERRETSRLVWTVVDANVQTLSCKVT-----KLLEGNEYTFR 16213

Query: 719   IFAVNAIGISKPSMPSRPFV---PLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLD 775
             I AVN  G+ +P + S P V   P  V   P    V +VT  ++ + W  P   G + + 
Sbjct: 16214 IMAVNKYGVGEP-LESEPVVAKNPFVVPDAPKAPEVTTVTKDSMIVVWERPASDGGSEIL 16272

Query: 776   GYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPI 835
             GYVLE   +    W   +K LI + +  +TGL  +     RV A NAAG SEP   S P 
Sbjct: 16273 GYVLEKRDKEGIRWTRCHKRLIGELRLRVTGLIENHDYEFRVSAENAAGLSEP---SPPS 16329

Query: 836   LVKEIIEP 843
               ++  +P
Sbjct: 16330 AYQKACDP 16337



 Score =  157 bits (398), Expect = 4e-38
 Identities = 101/319 (31%), Positives = 164/319 (51%), Gaps = 7/319 (2%)

Query: 531   DAYNVTLPAKV-HVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDK 589
             D   + LP  +   ++PP+I +    + +TV V AG+ L+++IPISG+P PK   SR D 
Sbjct: 19960 DPRELLLPVLIKEQLEPPEIDMKNFPS-HTVYVRAGSNLKVDIPISGKPLPKVTLSR-DG 20017

Query: 590   AIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPV 649
               ++ + R  TE   ++ T+ +  +   D+G Y I   N +G   A I + V+D P PP 
Sbjct: 20018 VPLKATMRFNTEITAENLTINLKESVTADAGRYEITAANSSGTTKAFINIVVLDRPGPPT 20077

Query: 650   APTV-TEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKK 708
              P V +++ ++   + WEPP YDGGS +  Y + +++  ++ W  ++  + + T  +  K
Sbjct: 20078 GPVVISDITEESVTLKWEPPKYDGGSQVTNYILLKRETSTAVWTEVSATVAR-TMMKVMK 20136

Query: 709   MIEGVAYEVRIFAVNAIGISK--PSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPP 766
             +  G  Y+ RI A N  GIS    S      +P     PP+   V +VT  ++T+ W  P
Sbjct: 20137 LTTGEEYQFRIKAENRFGISDHIDSACVTVKLPYTTPGPPSTPWVTNVTRESITVGWHEP 20196

Query: 767   DHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGAS 826
                G + + GY LE     +  W  ANK +I  T F +T +        RV A NAAG  
Sbjct: 20197 VSNGGSAVVGYHLEMKDRNSILWQKANKLVIRTTHFKVTTISAGLIYEFRVYAENAAGVG 20256

Query: 827   EPKYYSQPILVKEIIEPPK 845
             +P + S+P+L  +  EPP+
Sbjct: 20257 KPSHPSEPVLAIDACEPPR 20275



 Score =  157 bits (397), Expect = 5e-38
 Identities = 212/890 (23%), Positives = 342/890 (38%), Gaps = 93/890 (10%)

Query: 292  GGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTA 351
            G  V F+ EL   K+EV+W +N   +    K+    +G    L I + +  D  EY   A
Sbjct: 6429 GADVVFLAELNKDKVEVQWLRNNMVVVQGDKHQMMSEGKIHRLQICDIKPRDQGEYRFIA 6488

Query: 352  GDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSE-DDANVKWFKNGEEIIPGP 410
             D++   +L +   P + T   +D     G+ + +         A  +WFK  E     P
Sbjct: 6489 KDKEARAKLELAAAPKIKTAD-QDLVVDVGKPLTMVVPYDAYPKAEAEWFKENE-----P 6542

Query: 411  KSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLT--DQT 468
             S   I    ++    I  A K D   Y ++       A+  ++LK + +  P+   + T
Sbjct: 6543 LSTKTIDTTAEQTSFRILEAKKGDKGRYKIVLQNKHGKAEGFINLKVIDVPGPVRNLEVT 6602

Query: 469  VNLGKEICLKCEISENIPGKWTKN-GLPVQESD---RLKVVHKGRIHKLVIA-NALTEDE 523
                 E+ L  E  E +    +K  G  V+  D   +  V+   R          L +  
Sbjct: 6603 ETFDGEVSLAWE--EPLTDGGSKIIGYVVERRDIKRKTWVLATDRAESCEFTVTGLQKGG 6660

Query: 524  GDYVFAPDAYNVTLPAKVHVIDPP-----KIILDGLDADNTVTVIAGNKLRLEIPISGEP 578
             +Y+F   A N     +    D P     K  + G   + T+T +     R  + ++ EP
Sbjct: 6661 VEYLFRVSARNRVGTGEPVETDNPVEARSKYDVPGPPLNVTITDVN----RFGVSLTWEP 6716

Query: 579  PPKAMWSRGDKAIMEGSGRIR-------TESYPDSSTLVIDIAERDDSGVYHINLKNEAG 631
            P     +     ++E   +         T    D S  V D+ E  +   + +  +N  G
Sbjct: 6717 PEYDGGAEITNYVIELRDKTSIRWDTAMTVRAEDLSATVTDVVEGQEYS-FRVRAQNRIG 6775

Query: 632  EAHASIK---VKVVD---FPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKK 685
                S     VKV D    P PPV  T ++       + WEPP  DGGSPILGY IER +
Sbjct: 6776 VGKPSAATPFVKVADPIERPSPPVNLTSSDQTQSSVQLKWEPPLKDGGSPILGYIIERCE 6835

Query: 686  KQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGIS----------------K 729
            +    W+R N  L  E T++   + +G  Y  R+ A N  G+S                +
Sbjct: 6836 EGKDNWIRCNMKLVPELTYKVTGLEKGNKYLYRVSAENKAGVSDPSEILGPLTADDAFVE 6895

Query: 730  PSMPSRPF---VPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGT 786
            P+M    F   + + V +P T+L V S      T  W   D +   G    V        
Sbjct: 6896 PTMDLSAFKDGLEVIVPNPITIL-VPSTGYPRPTATWCFGDKVLETG--DRVKMKTLSAY 6952

Query: 787  EDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKI 846
             + +++  +  DK  +T+       K+  RVK ++  G  +    ++P   KE+      
Sbjct: 6953 AELVISPSERSDKGIYTL-------KLENRVKTIS--GEIDVNVIARPSAPKELKFGDIT 7003

Query: 847  RIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIR 906
            +   HL        G +       + +     TW K    +   +  + +         +
Sbjct: 7004 KDSVHLTWEPPDDDGGSPLTGYVVEKREVSRKTWTKVMDFVTDLEFTVPDLVQGKEYLFK 7063

Query: 907  KAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDG 966
               R+  G  +    VD+ V  ++        P PP+ VK  D    ++ LTW PPK+DG
Sbjct: 7064 VCARNKCGPGE-PAYVDEPVNMSTPATV----PDPPENVKWRDRTANSIFLTWDPPKNDG 7118

Query: 967  NAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATM 1026
             + I GY +++  + S +W    E    T   +T L  G  Y +RV + N  G S+ +  
Sbjct: 7119 GSRIKGYIVERCPRGSDKWVACGEPVAETKMEVTGLEEGKWYAYRVKALNRQGASKPSRP 7178

Query: 1027 TKESAVIARDGKIYKNPVYEDFDFSEAP---MFTQPLVNTYAIAGYNATLNCSVRGNPKP 1083
            T+E   +               D  EAP   +  + L      AG    L  +V G P+P
Sbjct: 7179 TEEIQAV---------------DTQEAPEIFLDVKLLAGLTVKAGTKIELPATVTGKPEP 7223

Query: 1084 KITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLG 1133
            KITW K  + +  D R  + +     T+ I      D GTY  +AVN  G
Sbjct: 7224 KITWTKADMILKQDKRITIENVPKKSTVTIVDSKRSDTGTYIIEAVNVCG 7273



 Score =  157 bits (397), Expect = 5e-38
 Identities = 146/550 (26%), Positives = 232/550 (42%), Gaps = 42/550 (7%)

Query: 385   ELEC-EVSEDDANVKWFK----NGEEII-----------PGPKSRYRIRVEGKKHILIIE 428
             ELE   +S+D   ++W K     G+EI+              K   + R++ K+    I 
Sbjct: 23939 ELEILSISKDSVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERIKDKQ--FTIG 23996

Query: 429   GATKADAAEYSVMT---TGGQSSAKLSVDLKPLK-------ILTPLTDQTVNLGKEICLK 478
             G  +A   E+ V     TG     + ++ +K          I   + D T  LG+   L 
Sbjct: 23997 GLLEATEYEFRVFAENETGLSRPRRTAMSIKTKLTSGEAPGIRKEMKDVTTKLGEAAQLS 24056

Query: 479   CEI-SENIPG-KWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDY--VFAPDAYN 534
             C+I    +P  KW + G  + +S + K+   GR H L +     EDEG Y  +   +   
Sbjct: 24057 CQIVGRPLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVGE 24116

Query: 535   VTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEG 594
             V   +K+ +   P+    G           G+ LRL +   G P P   W  G K +++ 
Sbjct: 24117 VETSSKLLLQATPQFH-PGYPLKEKYYGAVGSTLRLHVMYIGRPVPAMTWFHGQK-LLQN 24174

Query: 595   SGRIRTESYPDSSTLVI-DIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTV 653
             S  I  E+    + LV+ ++  +  +G Y + L N  G   A + V++ D PD P  P V
Sbjct: 24175 SENITIENTEHYTHLVMKNVQRKTHAGKYKVQLSNVFGTVDAILDVEIQDKPDKPTGPIV 24234

Query: 654   TE-VGDDWCIMNWEPPAYDGGSPILGYFIER-KKKQSSRWMRLNFDLCKETTFEPKKMIE 711
              E +  +  +++W+PPA DGGS I  Y +E+ + K+ + W  ++  +   TT     + E
Sbjct: 24235 IEALLKNSAVISWKPPADDGGSWITNYVVEKCEAKEGAEWQLVSSAI-SVTTCRIVNLTE 24293

Query: 712   GVAYEVRIFAVNAIGISKPSMPSRPFV---PLAVTSPPTLLTVDSVTDTTVTMRWRPPDH 768
                Y  R+ A N  GIS P   S   +   P      P   T+ +VT  +  + W+PP  
Sbjct: 24294 NAGYYFRVSAQNTFGISDPLEVSSVVIIKSPFEKPGAPGKPTITAVTKDSCVVAWKPPAS 24353

Query: 769   IGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEP 828
              G A +  Y LE   +    WI    + I +T F++  L    +   RVK  N  G SE 
Sbjct: 24354 DGGAKIRNYYLEKREKKQNKWISVTTEEIRETVFSVKNLIEGLEYEFRVKCENLGGESEW 24413

Query: 829   KYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEID 888
                S+PI  K  +          L+   +R    A  LV    G P+P + W + G EI 
Sbjct: 24414 SEISEPITPKSDVPIQAPHFKEELRNLNVRYQSNA-TLVCKVTGHPKPIVKWYRQGKEII 24472

Query: 889   KNQINIRNSE 898
              + +  R  E
Sbjct: 24473 ADGLKYRIQE 24482



 Score =  156 bits (395), Expect = 9e-38
 Identities = 103/340 (30%), Positives = 163/340 (47%), Gaps = 15/340 (4%)

Query: 516   ANALTEDEGDYVFAPDAYNVT---LPAKVHVIDPPKIILDGLDA----DNTVTVIAGNKL 568
             A  LTE + +Y F   A N      P+++ V+    ++   LD     D        +  
Sbjct: 13445 AKDLTEGK-EYTFRVSAENENGEGTPSEITVVARDDVVAPDLDLKGLPDLCYLAKENSNF 13503

Query: 569   RLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKN 628
             RL+IPI G+P P   W +G+  +   + R+  ES   ++TL++   ++ D+G Y I LKN
Sbjct: 13504 RLKIPIKGKPAPSVSWKKGEDPLATDT-RVSVESSAVNTTLIVYDCQKSDAGKYTITLKN 13562

Query: 629   EAGEAHASIKVKVVDFPDPPVAPT-VTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQ 687
              AG    +I +KVV  P  P  P    EV  +   + W PP  DGGS I  Y +E++   
Sbjct: 13563 VAGTKEGTISIKVVGKPGIPTGPIKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDSV 13622

Query: 688   SSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFV---PLAVTS 744
             +++W+       ++TTF   ++ EG+ Y  R+ A N  G+ +  + S P V   P  V  
Sbjct: 13623 NNKWVTCA-SAVQKTTFRVTRLHEGMEYTFRVSAENKYGVGE-GLKSEPIVARHPFDVPD 13680

Query: 745   PPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTI 804
              P    +  V   +V++ W  P   G + + GY LE+    +  W  ANK  I    F +
Sbjct: 13681 APPPPNIVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRANKTPIRMRDFKV 13740

Query: 805   TGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPP 844
             TGL    +   RV A+N AG  +P   S+P++  + I+PP
Sbjct: 13741 TGLTEGLEYEFRVMAINLAGVGKPSLPSEPVVALDPIDPP 13780



 Score =  155 bits (391), Expect = 3e-37
 Identities = 98/310 (31%), Positives = 156/310 (50%), Gaps = 8/310 (2%)

Query: 547   PKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDS 606
             P++ L G+     V   AG+ +++EIP+ G P P   W +GD+ I++ + R+  E+   S
Sbjct: 14566 PELDLRGI-YQKLVIAKAGDNIKVEIPVLGRPKPTVTWKKGDQ-ILKQTQRVNFETTATS 14623

Query: 607   STLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPT-VTEVGDDWCIMNW 665
             + L I+   R DSG Y +  +N  GE    I ++V D P PP  P    EV  D+   +W
Sbjct: 14624 TILNINECVRSDSGPYPLTARNIVGEVGDVITIQVHDIPGPPTGPIKFDEVSSDFVTFSW 14683

Query: 666   EPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAI 725
             +PP  DGG PI  Y +E ++  S+ W+ L   + + TT++  ++  G+ Y+ R+ A N  
Sbjct: 14684 DPPENDGGVPISNYVVEMRQTDSTTWVELATTVIR-TTYKATRLTTGLEYQFRVKAQNRY 14742

Query: 726   GISKPSMPSRPFV---PLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYC 782
             G+  P + S   V   P  V  PP    V +VT  ++T+ W  P   G + + GY +E  
Sbjct: 14743 GVG-PGITSACIVANYPFKVPGPPGTPQVTAVTKDSMTISWHEPLSDGGSPILGYHVERK 14801

Query: 783   FEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIE 842
                   W   +K L+    F  +GL        RV A N AG S+P   S+P+L  + I+
Sbjct: 14802 ERNGILWQTVSKALVPGNIFKSSGLTDGIAYEFRVIAENMAGKSKPSKPSEPMLALDPID 14861

Query: 843   PPKIRIPRHL 852
             PP   +P ++
Sbjct: 14862 PPGKPVPLNI 14871



 Score =  154 bits (389), Expect = 5e-37
 Identities = 103/318 (32%), Positives = 157/318 (49%), Gaps = 10/318 (3%)

Query: 530   PDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDK 589
             P   +V + AK  VI P   +L      NT TV+AG  L++++P  G P P   W + D 
Sbjct: 15635 PRQLSVPVIAKDLVIPPAFKLLF-----NTFTVLAGEDLKVDVPFIGRPTPAVTWHK-DN 15688

Query: 590   AIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPV 649
               ++ + R+  ES  ++S L I  A R+D G Y + L N AGEA  ++ V V+D P PP 
Sbjct: 15689 VPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAGEAIETLNVIVLDKPGPPT 15748

Query: 650   APT-VTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKK 708
              P  + EV  D   ++W PP YDGGS I  Y +E++   ++ W  ++  + + TT +  +
Sbjct: 15749 GPVKMDEVTADSITLSWGPPKYDGGSSINNYIVEKRDTSTTTWQIVSATVAR-TTIKACR 15807

Query: 709   MIEGVAYEVRIFAVNAIGISK--PSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPP 766
             +  G  Y+ RI A N  G S    S P+    P  V  PP    V   +  ++ ++W  P
Sbjct: 15808 LKTGCEYQFRIAAENRYGKSTYLNSEPTVAQYPFKVPGPPGTPVVTLSSRDSMEVQWNEP 15867

Query: 767   DHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGAS 826
                G + + GY LE     +  W+  NK  I +TKF  TGL    +   RV A N  G  
Sbjct: 15868 ISDGGSRVIGYHLERKERNSILWVKLNKTPIPQTKFKTTGLEEGVEYEFRVSAENIVGIG 15927

Query: 827   EPKYYSQPILVKEIIEPP 844
             +P   S+  + ++  +PP
Sbjct: 15928 KPSKVSECYVARDPCDPP 15945



 Score =  149 bits (375), Expect = 2e-35
 Identities = 97/304 (31%), Positives = 142/304 (46%), Gaps = 5/304 (1%)

Query: 544   IDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESY 603
             ID P   LD    D  + V AG    LE  I G+P P  +WS+  K + E + R+  +S 
Sbjct: 18205 IDAPNASLDPKYKD-VIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKST 18263

Query: 604   PDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPT-VTEVGDDWCI 662
                +TLV+    R D G Y + L N  G     I VKV+D P PP  P  VT V  + C 
Sbjct: 18264 IQKTTLVVKDCIRTDGGQYILKLSNVGGTKSIPITVKVLDRPGPPEGPLKVTGVTAEKCY 18323

Query: 663   MNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAV 722
             + W PP  DGG+ I  Y IE+++     W +++ ++ +   ++  K++ G  Y  R+ AV
Sbjct: 18324 LAWNPPLQDGGANISHYIIEKRETSRLSWTQVSTEV-QALNYKVTKLLPGNEYIFRVMAV 18382

Query: 723   NAIGISKP--SMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLE 780
             N  GI +P  S P     P     PP+   V ++T  ++ + W  P   G   ++GY+LE
Sbjct: 18383 NKYGIGEPLESGPVTACNPYKPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYILE 18442

Query: 781   YCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEI 840
                +    W   NK  +   +  +TGL        RV A NAAG  EP   S      + 
Sbjct: 18443 KRDKEGVRWTKCNKKTLTDLRLRVTGLTEGHSYEFRVAAENAAGVGEPSEPSVFYRACDA 18502

Query: 841   IEPP 844
             + PP
Sbjct: 18503 LYPP 18506



 Score =  146 bits (369), Expect = 1e-34
 Identities = 189/864 (21%), Positives = 334/864 (38%), Gaps = 120/864 (13%)

Query: 297  FVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKC 356
            F VEL+   + VKW+KN Q +  +     + +G    +   +  + D S+  V A     
Sbjct: 5451 FTVELSHDNIRVKWFKNDQRLHTTRSVSMQDEGKTHSITFKDLSIDDTSQIRVEAMGMSS 5510

Query: 357  STELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRI 416
              +L V E     T +L+D T    + V L+CE+S+ DA VKWFK+G+EI P   +   I
Sbjct: 5511 EAKLTVLEGDPYFTGKLQDYTGVEKDEVILQCEISKADAPVKWFKDGKEIKPSKNA--VI 5568

Query: 417  RVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEIC 476
            + +GKK +LI++ A K+D  +Y+      ++S KL ++ + +K++ PL    V   +   
Sbjct: 5569 KADGKKRMLILKKALKSDIGQYTCDCGTDKTSGKLDIEDREIKLVRPLHSVEVMETETAR 5628

Query: 477  LKCEISE-NIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNV 535
             + EISE +I   W   G  + ++   ++  +G+IH LV+ N   +  G   F   A NV
Sbjct: 5629 FETEISEDDIHANWKLKGEALLQTPDCEIKEEGKIHSLVLHNCRLDQTGGVDF--QAANV 5686

Query: 536  TLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGS 595
               A + V   P++I   L     VTV AG     +  +S E  P   + +G K  +E S
Sbjct: 5687 KSSAHLRV--KPRVI-GLLRPLKDVTVTAGETATFDCELSYEDIPVEWYLKGKK--LEPS 5741

Query: 596  GRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTE 655
             ++   S     TL +   + +D+G   +  K+    A+  +K   V+F  P    TV E
Sbjct: 5742 DKVVPRSEGKVHTLTLRDVKLEDAGEVQLTAKDFKTHANLFVKEPPVEFTKPLEDQTVEE 5801

Query: 656  VGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFE------PKKM 709
                            G + +L   + R+  +  +W +   ++ K   +E       +K+
Sbjct: 5802 ----------------GATAVLECEVSRENAK-VKWFKNGTEILKSKKYEIVADGRVRKL 5844

Query: 710  I--EGVAYEVRIFAVNA--------IGISKPSMP-SRPFVPLAVTSPPTLLTVDSVTDTT 758
            +  +    +++ +  +A        + +  P +   RP   L V           ++   
Sbjct: 5845 VIHDCTPEDIKTYTCDAKDFKTSCNLNVVPPHVEFLRPLTDLQVREKEMARFECELSREN 5904

Query: 759  VTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVK 818
              ++W      GA    G   +   +G    +V NK L+D           +A+    V+
Sbjct: 5905 AKVKWFKD---GAEIKKGKKYDIISKGAVRILVINKCLLD----------DEAEYSCEVR 5951

Query: 819  AVNAAG----ASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKP 874
                +G      E   +++ +   E+ E   I++   +                    KP
Sbjct: 5952 TARTSGMLTVLEEEAVFTKNLANIEVSETDTIKLVCEV-------------------SKP 5992

Query: 875  RPELTWKKDGAE-IDKNQINIRNSETDTIIFIRKAERSHSGKYDLQV---KVDKFVETAS 930
              E+ W K   E I+  +  I       I+ I+ A    +G Y+ ++   + D  V+   
Sbjct: 5993 GAEVIWYKGDEEIIETGRYEILTEGRKRILVIQNAHLEDAGNYNCRLPSSRTDGKVKVHE 6052

Query: 931  IDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQ-KADKKSMEWFTVI 989
            +  + I +P   +I++     GE      +  K+        + +Q K D K++E     
Sbjct: 6053 LAAEFISKPQNLEILE-----GEKAEFVCSISKE-------SFPVQWKRDDKTLE----- 6095

Query: 990  EHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFD 1049
                           G++Y      +    + +DAT+      +   G            
Sbjct: 6096 --------------SGDKYDVIADGKKRVLVVKDATLQDMGTYVVMVGAA---RAAAHLT 6138

Query: 1050 FSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVC 1109
              E      PL +T          NC V      K  W +N+ AI D  +Y +     V 
Sbjct: 6139 VIEKLRIVVPLKDTRVKEQQEVVFNCEV-NTEGAKAKWFRNEEAIFDSSKYIILQKDLVY 6197

Query: 1110 TLEIRKPSPYDGGTYCCKAVNDLG 1133
            TL IR     D   Y     N  G
Sbjct: 6198 TLRIRDAHLDDQANYNVSLTNHRG 6221



 Score =  146 bits (369), Expect = 1e-34
 Identities = 96/339 (28%), Positives = 169/339 (49%), Gaps = 21/339 (6%)

Query: 521   EDEGDYVF---APDAYNVTLPAK----VHVID---PPKIILDGLDADNTVTVIAGNKLRL 570
             E++  Y F   A  A N++ P++    V ++    PP+I L  +   + +TV AG  + L
Sbjct: 12760 EEKAQYQFRAIARTAVNISPPSEPSDPVTILAENVPPRIDLS-VAMKSLLTVKAGTNVCL 12818

Query: 571   EIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEA 630
             +  + G+P P   W + D  +++ +  I+     +  TL +    R DSG Y I  +N +
Sbjct: 12819 DATVFGKPMPTVSWKK-DGTLLKPAEGIKMAMQRNLCTLELFSVNRKDSGDYTITAENSS 12877

Query: 631   GEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSR 690
             G   A+IK+KV+D P PP +  + ++  D  +++WEPP  DGGS I  Y +++++     
Sbjct: 12878 GSKSATIKLKVLDKPGPPASVKINKMYSDRAMLSWEPPLEDGGSEITNYIVDKRETSRPN 12937

Query: 691   WMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGI-----SKPSMPSRPFVPLAVTSP 745
             W +++  +   T+   +K+IEG  Y+ RI A N  G+     ++P++   P+ P     P
Sbjct: 12938 WAQVSATV-PITSCSVEKLIEGHEYQFRICAENKYGVGDPVFTEPAIAKNPYDPPGRCDP 12996

Query: 746   PTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTIT 805
             P    + ++T   +T+ W+PP   G + + GY+LE       +W   N+  I +     T
Sbjct: 12997 P---VISNITKDHMTVSWKPPADDGGSPITGYLLEKRETQAVNWTKVNRKPIIERTLKAT 13053

Query: 806   GLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPP 844
             GL    +   RV A+N AG  +P   S+    ++   PP
Sbjct: 13054 GLQEGTEYEFRVTAINKAGPGKPSDASKAAYARDPQYPP 13092



 Score =  145 bits (365), Expect = 3e-34
 Identities = 110/374 (29%), Positives = 173/374 (46%), Gaps = 19/374 (5%)

Query: 288  QVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEY 347
            QV +    RF  EL+    +VKW+K+G EI+   KY    KG  RIL IN C + D++EY
Sbjct: 5887 QVREKEMARFECELSRENAKVKWFKDGAEIKKGKKYDIISKGAVRILVINKCLLDDEAEY 5946

Query: 348  YVTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEII 407
                   + S  L V E   + TK L +      + ++L CEVS+  A V W+K  EEII
Sbjct: 5947 SCEVRTARTSGMLTVLEEEAVFTKNLANIEVSETDTIKLVCEVSKPGAEVIWYKGDEEII 6006

Query: 408  PGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQ 467
                 RY I  EG+K IL+I+ A   DA  Y+      ++  K+ V     + ++   + 
Sbjct: 6007 --ETGRYEILTEGRKRILVIQNAHLEDAGNYNCRLPSSRTDGKVKVHELAAEFISKPQNL 6064

Query: 468  TVNLGKEICLKCEIS-ENIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDY 526
             +  G++    C IS E+ P +W ++   ++  D+  V+  G+   LV+ +A  +D G Y
Sbjct: 6065 EILEGEKAEFVCSISKESFPVQWKRDDKTLESGDKYDVIADGKKRVLVVKDATLQDMGTY 6124

Query: 527  VF----APDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKA 582
            V     A  A ++T+  K+ ++ P K        D  V          E+   G    KA
Sbjct: 6125 VVMVGAARAAAHLTVIEKLRIVVPLK--------DTRVKEQQEVVFNCEVNTEG---AKA 6173

Query: 583  MWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVV 642
             W R ++AI + S  I  +      TL I  A  DD   Y+++L N  GE   S    +V
Sbjct: 6174 KWFRNEEAIFDSSKYIILQK-DLVYTLRIRDAHLDDQANYNVSLTNHRGENVKSAANLIV 6232

Query: 643  DFPDPPVAPTVTEV 656
            +  D  +   + ++
Sbjct: 6233 EEEDLRIVEPLKDI 6246



 Score =  144 bits (362), Expect = 6e-34
 Identities = 89/302 (29%), Positives = 150/302 (49%), Gaps = 8/302 (2%)

Query: 547   PKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDS 606
             P   L G+  +  +T  AG+   +++PISG P PK  W   +  + E + R+   +  D 
Sbjct: 22148 PTADLTGI-TNQLITCKAGSPFTIDVPISGRPAPKVTWKLEEMRLKE-TDRVSITTTKDR 22205

Query: 607   STLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPT-VTEVGDDWCIMNW 665
             +TL +  + R DSG Y + L+N AG    S+ V V+  P P   P  V+ V  + C+++W
Sbjct: 22206 TTLTVKDSMRGDSGRYFLTLENTAGVKTFSVTVVVIGRPGPVTGPIEVSSVSAESCVLSW 22265

Query: 666   EPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAI 725
               P   GG+ I  Y +E+++  ++ W  +N  + K T  +   + + + Y  R+ + N  
Sbjct: 22266 GEPKDGGGTEITNYIVEKRESGTTAWQLVNSSV-KRTQIKVTHLTKYMEYSFRVSSENRF 22324

Query: 726   GISKPSMPSRPFV---PLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYC 782
             G+SKP + S P +   P    S PT   V  V+   +++RW  P H G + + GY +E  
Sbjct: 22325 GVSKP-LESAPIIAEHPFVPPSAPTRPEVYHVSANAMSIRWEEPYHDGGSKIIGYWVEKK 22383

Query: 783   FEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIE 842
                T  W+  NK    +  + +TGL    +   R  A+NAAG S+    S+PI+ +  ++
Sbjct: 22384 ERNTILWVKENKVPCLECNYKVTGLVEGLEYQFRTYALNAAGVSKASEASRPIMAQNPVD 22443

Query: 843   PP 844
              P
Sbjct: 22444 AP 22445



 Score =  142 bits (359), Expect = 1e-33
 Identities = 133/536 (24%), Positives = 207/536 (38%), Gaps = 70/536 (13%)

Query: 642  VDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKE 701
            +D P PP  PTV +VG     +NW  P +DGG+ I  Y IE  K  +  W+R+   +   
Sbjct: 7484 IDPPWPPGKPTVKDVGKTSVRLNWTKPEHDGGAKIESYVIEMLKTGTDEWVRVAEGVPTT 7543

Query: 702  TTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFV---PLAVTSPPTLLTVDSVTDTT 758
                P  M EG  Y  R+ AVN  G S+PS PS P +    L   SPP  L V ++T  T
Sbjct: 7544 QHLLPGLM-EGQEYSFRVRAVNKAGESEPSEPSDPVLCREKLYPPSPPRWLEVINITKNT 7602

Query: 759  VTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVK 818
              ++W  P+  G + +  Y++E      + W   +  + D TK T+T L   +    RV 
Sbjct: 7603 ADLKWTVPEKDGGSPITNYIVEKRDVRRKGWQTVDTTVKD-TKCTVTPLTEGSLYVFRVA 7661

Query: 819  AVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPEL 878
            A NA G S+       +L K+    P                G    L +    K   +L
Sbjct: 7662 AENAIGQSDYTEIEDSVLAKDTFTTP----------------GPPYALAVVDVTKRHVDL 7705

Query: 879  TW---KKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQI 935
             W   K DG    +  +  +     T    R  +   +   D   +V   +E   +  Q+
Sbjct: 7706 KWEPPKNDGGRPIQRYVIEKKERLGT----RWVKAGKTAGPDCNFRVTDVIEGTEVQFQV 7761

Query: 936  -----------------------IDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITG 972
                                      P PP  + + D   +++A+ W PP+ +G + I G
Sbjct: 7762 RAENEAGVGHPSEPTEILSIEDPTSPPSPPLDLHVTDAGRKHIAIAWKPPEKNGGSPIIG 7821

Query: 973  YTIQKADKKSMEWFTVIEHYHRTSATITE--LVIGNEYYFRVFSENMCGLSEDATMTKES 1030
            Y ++     + +W  V     +      E  +V   EY  RV + N  G+SE + +++  
Sbjct: 7822 YHVEMCPVGTEKWMRVNSRPIKDLKFKVEEGVVPDKEYVLRVRAVNAIGVSEPSEISEN- 7880

Query: 1031 AVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKN 1090
             V+A+D         E  D                I G   ++    R  P P ++W K+
Sbjct: 7881 -VVAKDPDCKPTIDLETHDI-------------IVIEGEKLSIPVPFRAVPVPTVSWHKD 7926

Query: 1091 KVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVKVI 1146
               +    R  M ++     LE+ K    D G Y     N LG+      + VKVI
Sbjct: 7927 GKEVKASDRLTMKNDHISAHLEVPKSVRADAGIYTITLENKLGSA--TASINVKVI 7980



 Score =  140 bits (352), Expect = 9e-33
 Identities = 91/298 (30%), Positives = 146/298 (48%), Gaps = 7/298 (2%)

Query: 546   PPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPD 605
             PPK  LD     + VT+ AG+ L L+  + G+P PK +W++GDK  ++   ++  +    
Sbjct: 22546 PPKAELDARLHGDLVTIRAGSDLVLDAAVGGKPEPKIIWTKGDKE-LDLCEKVSLQYTGK 22604

Query: 606   SSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNW 665
              +T VI   +R DSG Y + +KN +G    S+ VKV+D P P    TV+ V  + C + W
Sbjct: 22605 RATAVIKFCDRSDSGKYTLTVKNASGTKAVSVMVKVLDSPGPCGKLTVSRVTQEKCTLAW 22664

Query: 666   EPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAI 725
               P  DGG+ I  Y +ER++     W+ +  + C   ++   ++I+   Y  R+ AVN  
Sbjct: 22665 SLPQEDGGAEITHYIVERRETSRLNWVIVEGE-CPTLSYVVTRLIKNNEYIFRVRAVNKY 22723

Query: 726   GISKPSMPSRPFV---PLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYC 782
             G   P + S P V      + SPP +          + ++W  P+  G   +  Y+++  
Sbjct: 22724 GPGVP-VESEPIVARNSFTIPSPPGIPEEVGTGKEHIIIQWTKPESDGGNEISNYLVDKR 22782

Query: 783   FEGTEDWIVANKD-LIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKE 839
              + +  W   NKD ++  T+  +T L        RV AVNAAG SEP   S  I  +E
Sbjct: 22783 EKKSLRWTRVNKDYVVYDTRLKVTSLMEGCDYQFRVTAVNAAGNSEPSEASNFISCRE 22840



 Score =  139 bits (350), Expect = 2e-32
 Identities = 112/414 (27%), Positives = 188/414 (45%), Gaps = 21/414 (5%)

Query: 295  VRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDE 354
            + F V +    +  KW KNG EI+ + K     K     L I N    D ++Y   AG  
Sbjct: 2940 ITFEVTVNYEGISYKWLKNGVEIKSTDKCQMRTKKLTHSLNIRNVHFGDAADYTFVAGKA 2999

Query: 355  KCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRY 414
              +  L+V    I   K ++D      +R   ECEVSE D  V+W K+ +E+      R 
Sbjct: 3000 TSTATLYVEARHIEFRKHIKDIKVLEKKRAMFECEVSEPDITVQWMKDDQEL--QITDRI 3057

Query: 415  RIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKE 474
            +I+ E   H L+I     +DA +Y+V+  G  S+AKL V+ + ++I +   +  V   + 
Sbjct: 3058 KIQKEKYVHRLLIPSTRMSDAGKYTVVAGGNVSTAKLFVEGRDVRIRSIKKEVQVIEKQR 3117

Query: 475  ICLKCEISE-NIPGKWTKNGLPV--QESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPD 531
              ++ E++E ++   W K+G+ +  Q  +R K V + RIH++ I+     D G+Y F   
Sbjct: 3118 AVVEFEVNEDDVDAHWYKDGIEINFQVQERHKYVVERRIHRMFISETRQSDAGEYTFVAG 3177

Query: 532  AYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAI 591
                ++   V+  +PP++    L     VTV +G   R    ISG P PK  W + ++ +
Sbjct: 3178 RNRSSVTLYVNAPEPPQV----LQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLL 3233

Query: 592  MEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAG----EAHASIKVKVVDFPD- 646
              G  + +        TL++  A  +D+ VY    KN+ G     A  S++V  V  PD 
Sbjct: 3234 STGF-KCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQ 3292

Query: 647  --PPVAPTVTEVGDDWCIMNWEPPAY----DGGSPILGYFIERKKKQSSRWMRL 694
              P   P +     D      +P  +     G    + ++ + KK + SR+ R+
Sbjct: 3293 EMPVYPPAIITPLQDTVTSEGQPARFQCRVSGTDLKVSWYSKDKKIKPSRFFRM 3346



 Score =  139 bits (350), Expect = 2e-32
 Identities = 158/612 (25%), Positives = 260/612 (42%), Gaps = 77/612 (12%)

Query: 292   GGRVRFVVELAD-PKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVT 350
             GG +R  V +   P  EVKW K   EIR +   I +       L ++N    D  +Y +T
Sbjct: 16460 GGSLRLFVPIKGRPTPEVKWGKVDGEIRDAA--IIDVTSSFTSLVLDNVNRYDSGKYTLT 16517

Query: 351   AGDEKCSTELFVR-------EPPI--MVTKQLEDTTAYCGERVELECE-------VSEDD 394
               +   +   FV         PP+   VT+  +D+ +   E   L+         V + +
Sbjct: 16518 LENSSGTKSAFVTVRVLDTPSPPVNLKVTEITKDSVSITWEPPLLDGGSKIKNYIVEKRE 16577

Query: 395   ANVKWF--------KNG---EEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTT 443
             A  K +        KN    +++  G    +R+  E +  I        A  A+   +  
Sbjct: 16578 ATRKSYAAVVTNCHKNSWKIDQLQEGCSYYFRVTAENEYGI-----GLPAQTADPIKVAE 16632

Query: 444   GGQSSAKLSVDLKPLKILTPLTDQTVNLG---KEICLKCEISENIPGKWTKNGLPVQESD 500
               Q   K++VD         +T  +V+L     E     +I + I     K+     E  
Sbjct: 16633 VPQPPGKITVD--------DVTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKHSEKWSECA 16684

Query: 501   RLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYN-----------VTLPAKVHVIDPPKI 549
             R+K +      + VI N LT+ E +Y+F   A N           V + AK  VI+P   
Sbjct: 16685 RVKSL------QAVITN-LTQGE-EYLFRVVAVNEKGRSDPRSLAVPIVAKDLVIEP--- 16733

Query: 550   ILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTL 609
               D   A ++ +V  G  L++E+PISG P P   W++ D   ++ + RI      D +TL
Sbjct: 16734 --DVKPAFSSYSVQVGQDLKIEVPISGRPKPTITWTK-DGLPLKQTTRINVTDSLDLTTL 16790

Query: 610   VIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPT-VTEVGDDWCIMNWEPP 668
              I    +DD G Y I + N  G+  ASI++  +D PDPP  P    +V  +   ++W PP
Sbjct: 16791 SIKETHKDDGGQYGITVANVVGQKTASIEIVTLDKPDPPKGPVKFDDVSAESITLSWNPP 16850

Query: 669   AYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGIS 728
              Y GG  I  Y ++++   ++ W  ++  + + TT +  K+  G  Y+ RIFA N  G S
Sbjct: 16851 LYTGGCQITNYIVQKRDTTTTVWDVVSATVAR-TTLKVTKLKTGTEYQFRIFAENRYGQS 16909

Query: 729   KPSMPSRPFV---PLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEG 785
               ++ S P V   P     PP      +++  ++ ++W  P + G + + GY LE     
Sbjct: 16910 F-ALESDPIVAQYPYKEPGPPGTPFATAISKDSMVIQWHEPVNNGGSPVIGYHLERKERN 16968

Query: 786   TEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPK 845
             +  W   NK +I  T+F    L    +   RV A N  G  +    S+  + ++  +PP 
Sbjct: 16969 SILWTKVNKTIIHDTQFKAQNLEEGIEYEFRVYAENIVGVGKASKNSECYVARDPCDPPG 17028

Query: 846   IRIPRHLKQTYI 857
                P  +K+  I
Sbjct: 17029 TPEPIMVKRNEI 17040



 Score =  138 bits (347), Expect = 3e-32
 Identities = 89/302 (29%), Positives = 146/302 (48%), Gaps = 6/302 (1%)

Query: 547   PKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDS 606
             P I+  G +  + + + +G  LR++  + G P P+  W + D   +E    +       S
Sbjct: 21458 PPIVEFGPEYFDGLIIKSGESLRIKALVQGRPVPRVTWFK-DGVEIEKRMNMEITDVLGS 21516

Query: 607   STLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPT-VTEVGDDWCIMNW 665
             ++L +  A RD  GVY +  KN +G A A IKVKV D P   V P   T +  +   + W
Sbjct: 21517 TSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQDTPGKVVGPIRFTNITGEKMTLWW 21576

Query: 666   EPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAI 725
             + P  DG +PI  Y IE+++     W  +  D C+  ++   K+I G  Y+ R+ AVN  
Sbjct: 21577 DAPLNDGCAPITHYIIEKRETSRLAWALIE-DKCEAQSYTAIKLINGNEYQFRVSAVNKF 21635

Query: 726   GISKP--SMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCF 783
             G+ +P  S P    +   V   P +    ++T  ++T+ W  P+  G + +  Y+LE   
Sbjct: 21636 GVGRPLDSDPVVAQIQYTVPDAPGIPEPSNITGNSITLTWARPESDGGSEIQQYILERRE 21695

Query: 784   EGTEDWI-VANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIE 842
             + +  W+ V +K  I +T+F +TGL    +    V A NAAG       S+ I  +E + 
Sbjct: 21696 KKSTRWVKVISKRPISETRFKVTGLTEGNEYEFHVMAENAAGVGPASGISRLIKCREPVN 21755

Query: 843   PP 844
             PP
Sbjct: 21756 PP 21757



 Score =  136 bits (343), Expect = 1e-31
 Identities = 105/376 (27%), Positives = 169/376 (44%), Gaps = 13/376 (3%)

Query: 272  EEKKSAAFAKILDPAYQVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQ 331
            + K+   F + L      +K     F  E ++P ++VKWYK+G E+    KY        
Sbjct: 2123 QAKQLITFTQELQDVVAKEKDTMATFECETSEPFVKVKWYKDGMEVHEGDKYRMHSDRKV 2182

Query: 332  RILFINNCQMTDDSEY-YVTAGDE--KCSTELFVREPPIMVTKQLEDTTAYCGERVELEC 388
              L I     +D  +Y  V   DE  K + +L V    +   K+L+D         ELEC
Sbjct: 2183 HFLSILTIDTSDAEDYSCVLVEDENVKTTAKLIVEGAVVEFVKELQDIEVPESYSGELEC 2242

Query: 389  EVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSS 448
             VS ++   KW+ N  E+      +Y I     +  L ++  TK D  EYS +  G +++
Sbjct: 2243 IVSPENIEGKWYHNDVEL--KSNGKYTITSRRGRQNLTVKDVTKEDQGEYSFVIDGKKTT 2300

Query: 449  AKLSVDLKPLKILTPLTDQTVNLGKEICLKCEIS-ENIPGKWTKNGLPVQESDRLKVVHK 507
             KL +  +P+ IL  L+DQ V  G  + L+ ++S E++ G W K+G  VQ SDR+ +V  
Sbjct: 2301 CKLKMKPRPIAILQGLSDQKVCEGDIVQLEVKVSLESVEGVWMKDGQEVQPSDRVHIVID 2360

Query: 508  GRIHKLVIANALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNK 567
             + H L+I +   ED G+Y F   A  ++   +V V       +D +     V VI G K
Sbjct: 2361 KQSHMLLIEDMTKEDAGNYSFTIPALGLSTSGRVSVYS-----VDVITPLKDVNVIEGTK 2415

Query: 568  LRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLK 627
              LE  +S        W   D+ I +   R++         LVI+     D G Y + + 
Sbjct: 2416 AVLECKVSVPDVTSVKWYLNDEQI-KPDDRVQAIVKGTKQRLVINRTHASDEGPYKLIVG 2474

Query: 628  NEAGEAHASI-KVKVV 642
                  + S+ K+K++
Sbjct: 2475 RVETNCNLSVEKIKII 2490



 Score =  134 bits (338), Expect = 4e-31
 Identities = 201/832 (24%), Positives = 325/832 (39%), Gaps = 120/832 (14%)

Query: 362   VREPPIMVTKQLEDTTAY-CGERVELECEVS-EDDANVKWFKNGEEIIPGPKSRYRIRVE 419
             V  P I V  + +DT     GE   LE +VS      ++W K+G+E+     ++  I++ 
Sbjct: 14959 VEAPKIKVDVKFKDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKEL--EGTAKLEIKIA 15016

Query: 420   GKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKC 479
                  L+ + +T+ D+  Y++  T     AK   ++K L    P  +  + + +    KC
Sbjct: 15017 DFSTNLVNKDSTRRDSGAYTLTATNPGGFAKHIFNVKVLDRPGP-PEGPLAVTEVTSEKC 15075

Query: 480   EISENIP-----GKWTKNGLPVQESDRL---KVVHKGRIHKLVIANALTEDEGDY-VFAP 530
              +S   P      K     +  +E+ RL    V  + ++ KL +   L  +E  + V A 
Sbjct: 15076 VLSWFPPLDDGGAKIDHYIVQKRETSRLAWTNVASEVQVTKLKVTKLLKGNEYIFRVMAV 15135

Query: 531   DAYNVTLPAKVHVI---------DPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPK 581
             + Y V  P +   +         DPPK        +  VT I  + +   +   G P   
Sbjct: 15136 NKYGVGEPLESEPVLAVNPYGPPDPPK--------NPEVTTITKDSM---VVCWGHPDSD 15184

Query: 582   A-------MWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAG--- 631
                     +  R DKA      +   ++  D    V  + E  +   + I  +N AG   
Sbjct: 15185 GGSEIINYIVERRDKAGQRWI-KCNKKTLTDLRYKVSGLTEGHEYE-FRIMAENAAGISA 15242

Query: 632   EAHASIKVKVVDF---PDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQS 688
              +  S   K  D    P PP  P V +       + W  P YDGGS I GY +E    + 
Sbjct: 15243 PSPTSPFYKACDTVFKPGPPGNPRVLDTSRSSISIAWNKPIYDGGSEITGYMVEIALPEE 15302

Query: 689   SRWMRLNFDL-CKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSM-PSRPFVPLAVTSPP 746
               W  +      K T++    + E   Y++RI+A+N+ G+ +P++ P  P     +  P 
Sbjct: 15303 DEWQIVTPPAGLKATSYTITGLTENQEYKIRIYAMNSEGLGEPALVPGTPKAEDRMLPPE 15362

Query: 747   TLLTVDSVTDTT----------VTMRWRPPDHIGAAGLDGYVLEYC-FEGTEDW---IVA 792
               L  D     T          V ++ RP   +  A   G  L+    E T  +   IV 
Sbjct: 15363 IELDADLRKVVTIRACCTLRLFVPIKGRPAPEVKWARDHGESLDKASIESTSSYTLLIVG 15422

Query: 793   NKDLIDKTKF--TITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEII--------E 842
             N +  D  K+  T+         FV V+ ++  G        Q + VKE+         +
Sbjct: 15423 NVNRFDSGKYILTVENSSGSKSAFVNVRVLDTPGPP------QDLKVKEVTKTSVTLTWD 15476

Query: 843   PPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTI 902
             PP +     +K  YI    E+             + +WK D  +           E  + 
Sbjct: 15477 PPLLDGGSKIKN-YIVEKRESTRKAYSTVATNCHKTSWKVDQLQ-----------EGCSY 15524

Query: 903   IFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPP 962
              F   AE  +         +    ETA   ++  +RP PP  + + DV   +V+L+W  P
Sbjct: 15525 YFRVLAENEYG--------IGLPAETAE-SVKASERPLPPGKITLMDVTRNSVSLSWEKP 15575

Query: 963   KDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSE 1022
             + DG + I GY ++   K S +W T       T ATIT L+ G EY FRV ++N  G+S+
Sbjct: 15576 EHDGGSRILGYIVEMQTKGSDKWATCAT-VKVTEATITGLIQGEEYSFRVSAQNEKGISD 15634

Query: 1023  DATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAI-AGYNATLNCSVRGNP 1081
                ++    VIA+D  I              P   + L NT+ + AG +  ++    G P
Sbjct: 15635 PRQLSVP--VIAKDLVI--------------PPAFKLLFNTFTVLAGEDLKVDVPFIGRP 15678

Query: 1082  KPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLG 1133
              P +TW K+ V +    R    S +    L I+     D G Y  K  N  G
Sbjct: 15679 TPAVTWHKDNVPLKQTTRVNAESTENNSLLTIKDACREDVGHYVVKLTNSAG 15730



 Score =  131 bits (329), Expect = 4e-30
 Identities = 135/530 (25%), Positives = 203/530 (38%), Gaps = 77/530 (14%)

Query: 645   PDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNF-DLCKETT 703
             P PP  P V +       ++W  PAYDGGSPI+GY +E K+  S  W+R N     ++T 
Sbjct: 13092 PGPPAFPKVYDTTRSSVSLSWGKPAYDGGSPIIGYLVEVKRADSDNWVRCNLPQNLQKTR 13151

Query: 704   FEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPP----------TLLTVDS 753
             FE   ++E   Y+ R++AVN IG S PS       P  +  PP          TL+    
Sbjct: 13152 FEVTGLMEDTQYQFRVYAVNKIGYSDPSDVPDKHYPKDILIPPEGELDADLRKTLILRAG 13211

Query: 754   VT-DTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAK 812
             VT    V ++ RPP  I                   W   N +L D+    I    TD  
Sbjct: 13212 VTMRLYVPVKGRPPPKI------------------TWSKPNVNLRDRIGLDIKS--TDFD 13251

Query: 813   IFVRVKAVNAAGASE----------PKYYSQPILVKEIIEPP-KIRIPRHLKQT------ 855
              F+R + VN   A +           K Y+  + V +   PP  + +    K +      
Sbjct: 13252 TFLRCENVNKYDAGKYILTLENSCGKKEYTIVVKVLDTPGPPVNVTVKEISKDSAYVTWE 13311

Query: 856   --YIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHS 913
                I      +N V+  Q +     +W     E  K    + N E     F R    +  
Sbjct: 13312 PPIIDGGSPIINYVV--QKRDAERKSWSTVTTECSKTSFRVANLEEGKSYFFRVFAENEY 13369

Query: 914   GKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGY 973
             G  D     D         ++    PGP   +K+  V   + ++ W  P  DG + I GY
Sbjct: 13370 GIGDPGETRDA--------VKASQTPGPVVDLKVRSVSKSSCSIGWKKPHSDGGSRIIGY 13421

Query: 974   TIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVI 1033
              +    +++ +W  V++       +  +L  G EY FRV +EN  G    + +T    V+
Sbjct: 13422 VVDFLTEEN-KWQRVMKSL-SLQYSAKDLTEGKEYTFRVSAENENGEGTPSEIT----VV 13475

Query: 1034  ARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVA 1093
             ARD     + V  D D    P          A    N  L   ++G P P ++W K +  
Sbjct: 13476 ARD-----DVVAPDLDLKGLPDLCY-----LAKENSNFRLKIPIKGKPAPSVSWKKGEDP 13525

Query: 1094  IVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1143
             +  D R  + S+    TL +      D G Y     N  GT E    ++V
Sbjct: 13526 LATDTRVSVESSAVNTTLIVYDCQKSDAGKYTITLKNVAGTKEGTISIKV 13575



 Score =  130 bits (328), Expect = 5e-30
 Identities = 80/234 (34%), Positives = 120/234 (51%), Gaps = 8/234 (3%)

Query: 297  FVVELADPKLE-VKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEK 355
            F VEL  P ++ V+W KNG  +  + KY    KG    L I NC + D+S Y    G   
Sbjct: 2680 FTVELTHPNVKGVQWIKNGVVLESNEKYAISVKGTIYSLRIKNCAIVDESVYGFRLGRLG 2739

Query: 356  CSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYR 415
             S  L V    + + K+ +D TA     V  E  VS D   VKWF    EI P  K  +R
Sbjct: 2740 ASARLHVET--VKIIKKPKDVTALENATVAFEVSVSHDTVPVKWFHKSVEIKPSDK--HR 2795

Query: 416  IRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEI 475
            +  E K H L+++  + +DA EY+ +   GQ   K  + ++ L I   + +  V   K  
Sbjct: 2796 LVSERKVHKLMLQNISPSDAGEYTAVV--GQLECKAKLFVETLHITKTMKNIEVPETKTA 2853

Query: 476  CLKCEISE-NIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVF 528
              +CE+S  N+P  W KNG+ ++ S++ K+V +G++H+L+I N  TED  +Y F
Sbjct: 2854 SFECEVSHFNVPSMWLKNGVEIEMSEKFKIVVQGKLHQLIIMNTSTEDSAEYTF 2907



 Score =  129 bits (324), Expect = 2e-29
 Identities = 123/461 (26%), Positives = 196/461 (42%), Gaps = 58/461 (12%)

Query: 488   KWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDY--VFAPDAYNVTLPAKVHVID 545
             KWTK G  +  S R  +       +LVI  A   D G Y  V         +  KV VI 
Sbjct: 23672 KWTKEGQDI--SKRAMIATSETHTELVIKEADRGDSGTYDLVLENKCGKKAVYIKVRVIG 23729

Query: 546   PPKIILDGLDADNTVTVIAGNKLRLEIPISGEPP------------------PKAMWSRG 587
              P      L+ D+             + +S  PP                  PKA W   
Sbjct: 23730 SPNSPEGPLEYDDIQV--------RSVRVSWRPPADDGGADILGYILERREVPKAAWYTI 23781

Query: 588   DKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAG-----EAHASIKVKV- 641
             D        R+R       ++LV+   + +    + ++ +N+ G     ++   +  K  
Sbjct: 23782 DS-------RVR------GTSLVVKGLKENVEYHFRVSAENQFGISKPLKSEEPVTPKTP 23828

Query: 642   VDFPDPPV-APTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCK 700
             ++ P+PP   P V +V      ++W  P  DGGS + GY+IERK+  + +W+R N     
Sbjct: 23829 LNPPEPPSNPPEVLDVTKSSVSLSWSRPKDDGGSRVTGYYIERKETSTDKWVRHNKTQIT 23888

Query: 701   ETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFV---PLAVTSPPTLLTVDSVTDT 757
              T +    ++    Y+ RI A N +G+S+ S  S P V   P    S P  L + S++  
Sbjct: 23889 TTMYTVTGLVPDAEYQFRIIAQNDVGLSETSPASEPVVCKDPFDKPSQPGELEILSISKD 23948

Query: 758   TVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRV 817
             +VT++W  P+  G   + GY +EY   G   W  +NK+ I   +FTI GL    +   RV
Sbjct: 23949 SVTLQWEKPECDGGKEILGYWVEYRQSGDSAWKKSNKERIKDKQFTIGGLLEATEYEFRV 24008

Query: 818   KAVNAAGASEPKYYSQPILVKEII-EPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRP 876
              A N  G S P+  +  I  K    E P IR  + +K     ++GEA  L     G+P P
Sbjct: 24009 FAENETGLSRPRRTAMSIKTKLTSGEAPGIR--KEMKDV-TTKLGEAAQLSCQIVGRPLP 24065

Query: 877   ELTWKKDGAEIDKNQINIRNSETDT-IIFIRKAERSHSGKY 916
             ++ W + G E+ +++    +S+  T  + +   E+   G Y
Sbjct: 24066 DIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVY 24106



 Score =  128 bits (322), Expect = 3e-29
 Identities = 101/352 (28%), Positives = 164/352 (46%), Gaps = 15/352 (4%)

Query: 289  VDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYY 348
            V +G    FV EL+  K+ V W+KN  ++  S   +   +G    L +    + D S+  
Sbjct: 5088 VKEGETATFVCELSHEKMHVVWFKNDAKLHTSRTVLISSEGKTHKLEMKEVTLDDISQIK 5147

Query: 349  VTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIP 408
                +   + +L V E     T +L D TA   + + L+CEVS+ D  VKWFK+GEEI+P
Sbjct: 5148 AQVKELSSTAQLKVLEADPYFTVKLHDKTAVEKDEITLKCEVSK-DVPVKWFKDGEEIVP 5206

Query: 409  GPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQT 468
             PK  Y I+ +G + IL I+ A   D  EY       ++ A ++V+ + +K+  PL    
Sbjct: 5207 SPK--YSIKADGLRRILKIKKADLKDKGEYVCDCGTDKTKANVTVEARLIKVEKPLYGVE 5264

Query: 469  VNLGKEICLKCEISE-NIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYV 527
            V +G+    + E+SE ++ G+W   G P+  S   +++  G+ H L++ N      G+  
Sbjct: 5265 VFVGETAHFEIELSEPDVHGQWKLKGQPLTASPDCEIIEDGKKHILILHNCQLGMTGEVS 5324

Query: 528  FAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRG 587
            F   A N    A + V + P I +  L   + V V   ++ + E  +S E P    W +G
Sbjct: 5325 F--QAANAKSAANLKVKELPLIFITPL---SDVKVFEKDEAKFECEVSRE-PKTFRWLKG 5378

Query: 588  DKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKV 639
             + I  G  R          ++VI  A  +D   Y      EA + H S K+
Sbjct: 5379 TQEI-TGDDRFELIKDGTKHSMVIKSAAFEDEAKYMF----EAEDKHTSGKL 5425



 Score =  127 bits (320), Expect = 5e-29
 Identities = 123/540 (22%), Positives = 217/540 (40%), Gaps = 60/540 (11%)

Query: 622   YHINLKNEAG---EAHASIKVKVVD---FPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSP 675
             Y +  +N AG    +  S  ++  D    P PP  P + + G     + W  P +DGG+P
Sbjct: 19558 YRVYAENAAGLSLPSETSPLIRAEDPVFLPSPPSKPKIVDSGKTTITIAWVKPLFDGGAP 19617

Query: 676   ILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSR 735
             I GY +E KK   + W + +    + T +    +  G  Y  R+ +VN +G S PS  S 
Sbjct: 19618 ITGYTVEYKKSDDTDW-KTSIQSLRGTEYTISGLTTGAEYVFRVKSVNKVGASDPSDSSD 19676

Query: 736   PFVPLAVTSPP----------TLLTVDSVTDT-TVTMRWRPPDHIGAAGLDGYVLEYCFE 784
             P +       P          TL+     + T TV  R RP  ++  +  D  +    + 
Sbjct: 19677 PQIAKEREEEPLFDIDSEMRKTLIVKAGASFTMTVPFRGRPVPNVLWSKPDTDLRTRAYV 19736

Query: 785   GTED----WIVANKDLIDKTKFTIT--GLPTDAKIFVRVKAVNAAGASEPKYYSQPILVK 838
              T D      + N +  D  K+T+T   + + A + + VK ++  G          I V+
Sbjct: 19737 DTTDSRTSLTIENANRNDSGKYTLTIQNVLSAASLTLVVKVLDTPGPPTN------ITVQ 19790

Query: 839   EIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSE 898
             ++ +   +     L        G A       + +   +  W       ++    + N +
Sbjct: 19791 DVTKESAV-----LSWDVPENDGGAPVKNYHIEKREASKKAWVSVTNNCNRLSYKVTNLQ 19845

Query: 899   TDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALT 958
                I + R      SG+ +  V +    ET    ++I ++P PP+ + +  +  ++V+LT
Sbjct: 19846 EGAIYYFRV-----SGENEFGVGIP--AETKE-GVKITEKPSPPEKLGVTSISKDSVSLT 19897

Query: 959   WTPPKDDGNAAITGYTIQKADKKSMEWF--TVIEHYHRTSATITELVIGNEYYFRVFSEN 1016
             W  P+ DG + I  Y ++  +K    W    V +  H   + + E    +EY+FRVF+EN
Sbjct: 19898 WLKPEHDGGSRIVHYVVEALEKGQKNWVKCAVAKSTHHVVSGLRE---NSEYFFRVFAEN 19954

Query: 1017  MCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCS 1076
               GLS+   +            +    + E  +  E  M   P    Y  AG N  ++  
Sbjct: 19955 QAGLSDPREL------------LLPVLIKEQLEPPEIDMKNFPSHTVYVRAGSNLKVDIP 20002

Query: 1077  VRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVE 1136
             + G P PK+T  ++ V +    R+         T+ +++    D G Y   A N  GT +
Sbjct: 20003 ISGKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADAGRYEITAANSSGTTK 20062



 Score =  125 bits (315), Expect = 2e-28
 Identities = 87/266 (32%), Positives = 123/266 (46%), Gaps = 11/266 (4%)

Query: 272  EEKKSAAFAKIL--DPAYQV---DKGGRVRFVVEL---ADPKLEVKWYKNGQEIRPSTKY 323
            +E  S A  K+L  DP + V   DK    +  + L       + VKW+K+G+EI PS KY
Sbjct: 5151 KELSSTAQLKVLEADPYFTVKLHDKTAVEKDEITLKCEVSKDVPVKWFKDGEEIVPSPKY 5210

Query: 324  IFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGER 383
              +  G +RIL I    + D  EY    G +K    + V    I V K L     + GE 
Sbjct: 5211 SIKADGLRRILKIKKADLKDKGEYVCDCGTDKTKANVTVEARLIKVEKPLYGVEVFVGET 5270

Query: 384  VELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTT 443
               E E+SE D + +W   G+ +   P     I  +GKKHILI+         E S    
Sbjct: 5271 AHFEIELSEPDVHGQWKLKGQPLTASPDC--EIIEDGKKHILILHNCQLGMTGEVSFQAA 5328

Query: 444  GGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCEIS-ENIPGKWTKNGLPVQESDRL 502
              +S+A L V   PL  +TPL+D  V    E   +CE+S E    +W K    +   DR 
Sbjct: 5329 NAKSAANLKVKELPLIFITPLSDVKVFEKDEAKFECEVSREPKTFRWLKGTQEITGDDRF 5388

Query: 503  KVVHKGRIHKLVIANALTEDEGDYVF 528
            +++  G  H +VI +A  EDE  Y+F
Sbjct: 5389 ELIKDGTKHSMVIKSAAFEDEAKYMF 5414



 Score =  122 bits (306), Expect = 2e-27
 Identities = 197/849 (23%), Positives = 321/849 (37%), Gaps = 123/849 (14%)

Query: 344   DSEYYVTAGDEKCSTELFVREPPIMVTKQLEDTTAY-CGERVELECEV-SEDDANVKWFK 401
             DS   +TA DE       V  P I +  +  DT     GE   LE +V  +    ++W +
Sbjct: 17112 DSTGPITAKDE-------VELPRISMDPKFRDTIVVNAGETFRLEADVHGKPLPTIEWLR 17164

Query: 402   NGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKIL 461
               +EI     +R  I+    K +LI++ A + D  +Y +  +    S    V++K L   
Sbjct: 17165 GDKEI--EESARCEIKNTDFKALLIVKDAIRIDGGQYILRASNVAGSKSFPVNVKVLDRP 17222

Query: 462   TPLTDQTVNLGKEICLKCEISENIPGKWTKNGLPVQESDRLKVVHKGRIHKL-------- 513
              P  +  V +      KC ++ + P +    G  +       VV K    +L        
Sbjct: 17223 GP-PEGPVQVTGVTSEKCSLTWSPPLQ--DGGSDISHY----VVEKRETSRLAWTVVASE 17275

Query: 514   VIANALTEDE----GDYVF---APDAYNVTLPAK-VHVIDPPKIILDGLDADNTVTVIAG 565
             V+ N+L   +     +YVF   A + Y V  P +   V+     +L G      VT IA 
Sbjct: 17276 VVTNSLKVTKLLEGNEYVFRIMAVNKYGVGEPLESAPVLMKNPFVLPGPPKSLEVTNIAK 17335

Query: 566   NKLRLEIPISGEPPPKAMWSRGDKA--------IMEGSGRIRTESYPDSSTLVIDIAER- 616
             + + +             W+R D          I+E   R        +   + D+  R 
Sbjct: 17336 DSMTV------------CWNRPDSDGGSEIIGYIVEKRDRSGIRWIKCNKRRITDLRLRV 17383

Query: 617   -----DDSGVYHINLKNEAGEAH---ASIKVKVVD---FPDPPVAPTVTEVGDDWCIMNW 665
                  D    + ++ +N AG      A++  K  D    P PP    + +   +   + W
Sbjct: 17384 TGLTEDHEYEFRVSAENAAGVGEPSPATVYYKACDPVFKPGPPTNAHIVDTTKNSITLAW 17443

Query: 666   EPPAYDGGSPILGYFIERKKKQSSRWMRLNFDL-CKETTFEPKKMIEGVAYEVRIFAVNA 724
               P YDGGS ILGY +E  K     W  +      + T FE  K+ E   Y++R+ A+N 
Sbjct: 17444 GKPIYDGGSEILGYVVEICKADEEEWQIVTPQTGLRVTRFEISKLTEHQEYKIRVCALNK 17503

Query: 725   IGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMR------------WRPPDHIGAA 772
             +G+ + +       P      P L  +DS     + +R             RP   I  +
Sbjct: 17504 VGLGEATSVPGTVKPEDKLEAPEL-DLDSELRKGIVVRAGGSARIHIPFKGRPTPEITWS 17562

Query: 773   GLDG-YVLEYCFEGTEDWI---VANKDLIDKTKFTIT--GLPTDAKIFVRVKAVNAAGAS 826
               +G +  +   E   ++    + N D  D  K+ +           FV VK ++  G  
Sbjct: 17563 REEGEFTDKVQIEKGVNYTQLSIDNCDRNDAGKYILKLENSSGSKSAFVTVKVLDTPGPP 17622

Query: 827   EPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAE 886
                   Q + VKE+ +     +    +   I    +  N VI  +   R    +    ++
Sbjct: 17623 ------QNLAVKEVRKDSAFLV---WEPPIIDGGAKVKNYVIDKRESTRK--AYANVSSK 17671

Query: 887   IDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVK 946
               K    + N     I + R    +  G       V   VET    ++  + P PP  V 
Sbjct: 17672 CSKTSFKVENLTEGAIYYFRVMAENEFG-------VGVPVETVDA-VKAAEPPSPPGKVT 17723

Query: 947   IEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGN 1006
             + DV   + +L W  P+ DG + + GY ++   K + +W  V E     +A +T L  G 
Sbjct: 17724 LTDVSQTSASLMWEKPEHDGGSRVLGYVVEMQPKGTEKWSIVAES-KVCNAVVTGLSSGQ 17782

Query: 1007  EYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAI 1066
             EY FRV + N  G S+   +     VIA+D  I              P    P  NTY+I
Sbjct: 17783 EYQFRVKAYNEKGKSDPRVLGVP--VIAKDLTIQ-------------PSLKLPF-NTYSI 17826

Query: 1067  -AGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYC 1125
              AG +  +   V G P+P I+W+K+   +    R  +        L I++ +  D G Y 
Sbjct: 17827 QAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFGKYT 17886

Query: 1126  CKAVNDLGT 1134
               A N  GT
Sbjct: 17887 VTATNSAGT 17895



 Score =  121 bits (304), Expect = 3e-27
 Identities = 185/870 (21%), Positives = 323/870 (37%), Gaps = 146/870 (16%)

Query: 338   NCQMTDDSEYYVTAGDEKCSTELFVREPPIMVTKQLEDT-TAYCGERVELECEV-SEDDA 395
             N     DS   +TA DE       +  P   +  + +D    + GE   LE ++  +   
Sbjct: 18188 NFSEPSDSSGAITARDE-------IDAPNASLDPKYKDVIVVHAGETFVLEADIRGKPIP 18240

Query: 396   NVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEY--SVMTTGGQSSAKLSV 453
             +V W K+G+E+     +R  I+   +K  L+++   + D  +Y   +   GG  S  ++V
Sbjct: 18241 DVVWSKDGKEL-EETAARMEIKSTIQKTTLVVKDCIRTDGGQYILKLSNVGGTKSIPITV 18299

Query: 454   DLK--------PLKIL------------TPLTDQTVNLGKEICLKCEISENIPGKWTKNG 493
              +         PLK+              PL D   N+   I  K E S      WT+  
Sbjct: 18300 KVLDRPGPPEGPLKVTGVTAEKCYLAWNPPLQDGGANISHYIIEKRETSRL---SWTQVS 18356

Query: 494   LPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVF---APDAYNVTLPAKVHVID----- 545
               VQ  +        ++ KL+  N       +Y+F   A + Y +  P +   +      
Sbjct: 18357 TEVQALNY-------KVTKLLPGN-------EYIFRVMAVNKYGIGEPLESGPVTACNPY 18402

Query: 546   -----PPKIILDGLDADNTVTVIA------GNKLRLEIPISGEPPPKAMWSRGDKAIMEG 594
                  P    +  +  D+ V   A      G ++   I +         W++ +K  +  
Sbjct: 18403 KPPGPPSTPEVSAITKDSMVVTWARPVDDGGTEIEGYI-LEKRDKEGVRWTKCNKKTLTD 18461

Query: 595   SGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGE-AHASIKVKVVDF---PDPPVA 650
               R+R     +  +    +A  + +GV         GE +  S+  +  D    P PP  
Sbjct: 18462 L-RLRVTGLTEGHSYEFRVAAENAAGV---------GEPSEPSVFYRACDALYPPGPPSN 18511

Query: 651   PTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETT------F 704
             P VT+       + W  P YDGG+P+ GY +E K+  +  W       C   T      F
Sbjct: 18512 PKVTDTSRSSVSLAWSKPIYDGGAPVKGYVVEVKEAAADEWTT-----CTPPTGLQGKQF 18566

Query: 705   EPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTL-----------LTVDS 753
                K+ E   Y  RI A+N+ G+ +P+      V      PP +           L   +
Sbjct: 18567 TVTKLKENTEYNFRICAINSEGVGEPATLPGSVVAQERIEPPEIELDADLRKVVVLRASA 18626

Query: 754   VTDTTVTMRWRPPDHIGAAGLDGYVLEYC-FEGTEDW---IVANKDLIDKTKFTIT--GL 807
                  VT++ RP   +     +G + +    E T  +   ++ N    D  ++ +T    
Sbjct: 18627 TLRLFVTIKGRPEPEVKWEKAEGILTDRAQIEVTSSFTMLVIDNVTRFDSGRYNLTLENN 18686

Query: 808   PTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLV 867
                   FV V+ +++  A        P+ +  I E  K  +    +   I    +  N +
Sbjct: 18687 SGSKTAFVNVRVLDSPSA--------PVNLT-IREVKKDSVTLSWEPPLIDGGAKITNYI 18737

Query: 868   IPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVE 927
             +  +   R       +     K    I N +     + R      S +Y + +  +    
Sbjct: 18738 VEKRETTRKAYATITNNCT--KTTFRIENLQEGCSYYFRVLA---SNEYGIGLPAE---- 18788

Query: 928   TASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFT 987
               +  +++ + P PP  V + DV      + W  P+ DG + ITGY ++   K S +W T
Sbjct: 18789 -TTEPVKVSEPPLPPGRVTLVDVTRNTATIKWEKPESDGGSKITGYVVEMQTKGSEKWST 18847

Query: 988   VIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYED 1047
               +      ATI+ L  G EY FRV + N  G S+   +     VIARD +I        
Sbjct: 18848 CTQ-VKTLEATISGLTAGEEYVFRVAAVNEKGRSDPRQLGVP--VIARDIEI-------- 18896

Query: 1048  FDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQG 1107
                   P    P       A     ++   +G P+  + W K+   + +  R  + S++ 
Sbjct: 18897 -----KPSVELPFHTFNVKAREQLKIDVPFKGRPQATVNWRKDGQTLKETTRVNVSSSKT 18951

Query: 1108  VCTLEIRKPSPYDGGTYCCKAVNDLGTVEI 1137
             V +L I++ S  D GTY     N  G++ +
Sbjct: 18952 VTSLSIKEASKEDVGTYELCVSNSAGSITV 18981



 Score =  120 bits (302), Expect = 6e-27
 Identities = 142/561 (25%), Positives = 214/561 (38%), Gaps = 83/561 (14%)

Query: 622   YHINLKNEAGEAHASIKVKVVDF------PDPPVAPTVTEVGDDWCIMNWEPPAYDGGSP 675
             + ++ +NE G    S   K V        P PPV P   +   +   + W+PP +DGGS 
Sbjct: 10587 FRVSAENEIGIGDPSPPSKPVFAKDPIAKPSPPVNPEAIDTTCNSVDLTWQPPRHDGGSK 10646

Query: 676   ILGYFIERKKKQSSRWMRLNF--DLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMP 733
             ILGY +E +K     W R N   + C ET ++   + +G  Y+ R+ AVNA G S P+  
Sbjct: 10647 ILGYIVEYQKVGDEEWRRANHTPESCPETKYKVTGLRDGQTYKFRVLAVNAAGESDPAHV 10706

Query: 734   SRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTE----DW 789
               P +      PP L     + D  +        HI     D   L    +G       W
Sbjct: 10707 PEPVLVKDRLEPPEL-----ILDANMARE----QHIKVG--DTLRLSAIIKGVPFPKVTW 10755

Query: 790   IVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAG----ASEPKYYSQPILVKEIIEPPK 845
                ++D   K +  +T  P  +K+ +R  A    G      E    S+ + VK ++   K
Sbjct: 10756 KKEDRDAPTKARIDVT--PVGSKLEIRNAAHEDGGIYSLTVENPAGSKTVSVKVLVLD-K 10812

Query: 846   IRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKK---DGAEIDKNQINIRNSETD-- 900
                PR L+ + IR              K    LTWK+   DG  +  N +  R       
Sbjct: 10813 PGPPRDLEVSEIR--------------KDSCYLTWKEPLDDGGSVITNYVVERRDVASAQ 10858

Query: 901   -TIIFIRKAERSHSGKY-------------DLQVKVDKFVETASIDIQIIDR---PGPPQ 943
              + +     ++SH  K+             + Q     FVET    I+ +D    PGPP+
Sbjct: 10859 WSPLSATSKKKSHFAKHLNEGNQYLFRVAAENQYGRGPFVETPK-PIKALDPLHPPGPPK 10917

Query: 944   IVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELV 1003
              +   DV    V+L W  P  DG + ITGY ++  ++ + +W    +        +T L 
Sbjct: 10918 DLHHVDVDKTEVSLVWNKPDRDGGSPITGYLVEYQEEGTQDWIK-FKTVTNLECVVTGLQ 10976

Query: 1004  IGNEYYFRVFSENMCGLS-EDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVN 1062
              G  Y FRV +EN+ GL   D T+  E        K+    V  D    E  +       
Sbjct: 10977 QGKTYRFRVKAENIVGLGLPDTTIPIEC-----QEKLVPPSVELDVKLIEGLVVK----- 11026

Query: 1063  TYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGG 1122
                 AG        +RG P P   W  +   I  D  Y + ++     L I+     D G
Sbjct: 11027 ----AGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTG 11082

Query: 1123  TYCCKAVNDLGTVEIECKLEV 1143
              Y     N  G+  +   L V
Sbjct: 11083 EYQITVSNAAGSKTVAVHLTV 11103



 Score =  120 bits (301), Expect = 7e-27
 Identities = 130/513 (25%), Positives = 208/513 (40%), Gaps = 41/513 (7%)

Query: 121  KGKWMDLASKAGKHLQLKETFERHSRVYTFEMQIIKAKDNFAGNYRCEVTYKDKFDSCSF 180
            KG+W+    + GKHL L       S  +   + I   K +  G Y    TYK      S 
Sbjct: 2603 KGEWL----RDGKHLPLTNNIRSESDGHKRRLIIAATKLDDIGEY----TYKVATSKTSA 2654

Query: 181  DLEVH--ESTGTTPNIDIRSAFKRSGEGQEDAGELDFSGLLKRREVKQQEEEPQVDVWEL 238
             L+V   +   T  N+ +          +     +     +K   V +  E+  + V   
Sbjct: 2655 KLKVEAVKIKKTLKNLTVTETQDAVFTVELTHPNVKGVQWIKNGVVLESNEKYAISV--- 2711

Query: 239  LKNAKPSEYEKIAFQYGITDLRGMLKRLKRMRREEKKSAAFAKILDPAYQVD--KGGRVR 296
                K + Y        I D      RL R+    +      KI+     V   +   V 
Sbjct: 2712 ----KGTIYSLRIKNCAIVDESVYGFRLGRLGASARLHVETVKIIKKPKDVTALENATVA 2767

Query: 297  FVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKC 356
            F V ++   + VKW+    EI+PS K+    +     L + N   +D  EY    G  +C
Sbjct: 2768 FEVSVSHDTVPVKWFHKSVEIKPSDKHRLVSERKVHKLMLQNISPSDAGEYTAVVGQLEC 2827

Query: 357  STELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRI 416
              +LFV    + +TK +++      +    ECEVS  +    W KNG EI    K  ++I
Sbjct: 2828 KAKLFVE--TLHITKTMKNIEVPETKTASFECEVSHFNVPSMWLKNGVEIEMSEK--FKI 2883

Query: 417  RVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEIC 476
             V+GK H LII   +  D+AEY+ +    Q SA L+V   P+ I + L D  +N  ++  
Sbjct: 2884 VVQGKLHQLIIMNTSTEDSAEYTFVCGNDQVSATLTV--TPIMITSMLKD--INAEEKDT 2939

Query: 477  LKCEISENIPG---KWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPD-- 531
            +  E++ N  G   KW KNG+ ++ +D+ ++  K   H L I N    D  DY F     
Sbjct: 2940 ITFEVTVNYEGISYKWLKNGVEIKSTDKCQMRTKKLTHSLNIRNVHFGDAADYTFVAGKA 2999

Query: 532  AYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAI 591
                TL  +   I+  K I D       + V+   +   E  +S EP     W + D+  
Sbjct: 3000 TSTATLYVEARHIEFRKHIKD-------IKVLEKKRAMFECEVS-EPDITVQWMKDDQE- 3050

Query: 592  MEGSGRIRTESYPDSSTLVIDIAERDDSGVYHI 624
            ++ + RI+ +       L+I      D+G Y +
Sbjct: 3051 LQITDRIKIQKEKYVHRLLIPSTRMSDAGKYTV 3083



 Score =  120 bits (301), Expect = 7e-27
 Identities = 89/317 (28%), Positives = 143/317 (45%), Gaps = 11/317 (3%)

Query: 281  KILDPAYQVD--KGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINN 338
            K++ P + V+  +    RF  E+++  +   W   G+ +  +     + +G    L ++N
Sbjct: 5611 KLVRPLHSVEVMETETARFETEISEDDIHANWKLKGEALLQTPDCEIKEEGKIHSLVLHN 5670

Query: 339  CQMTDDSEYYVTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVK 398
            C++         A + K S  L V+   I + + L+D T   GE    +CE+S +D  V+
Sbjct: 5671 CRLDQTGGVDFQAANVKSSAHLRVKPRVIGLLRPLKDVTVTAGETATFDCELSYEDIPVE 5730

Query: 399  WFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPL 458
            W+  G+++ P  K     R EGK H L +      DA E  +     ++ A L V   P+
Sbjct: 5731 WYLKGKKLEPSDK--VVPRSEGKVHTLTLRDVKLEDAGEVQLTAKDFKTHANLFVKEPPV 5788

Query: 459  KILTPLTDQTVNLGKEICLKCEIS-ENIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIAN 517
            +   PL DQTV  G    L+CE+S EN   KW KNG  + +S + ++V  GR+ KLVI +
Sbjct: 5789 EFTKPLEDQTVEEGATAVLECEVSRENAKVKWFKNGTEILKSKKYEIVADGRVRKLVIHD 5848

Query: 518  ALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGE 577
               ED   Y    DA +      ++V+ P    L  L     + V      R E  +S E
Sbjct: 5849 CTPEDIKTYTC--DAKDFKTSCNLNVVPPHVEFLRPL---TDLQVREKEMARFECELSRE 5903

Query: 578  PPPKAMWSRGDKAIMEG 594
               K  W +    I +G
Sbjct: 5904 -NAKVKWFKDGAEIKKG 5919



 Score =  119 bits (298), Expect = 2e-26
 Identities = 113/439 (25%), Positives = 181/439 (41%), Gaps = 46/439 (10%)

Query: 621   VYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYF 680
             V  INL      +  S  V  +D  DPP  P V  +  +   + W  P YDGG  + GY 
Sbjct: 13753 VMAINLAGVGKPSLPSEPVVALDPIDPPGKPEVINITRNSVTLIWTEPKYDGGHKLTGYI 13812

Query: 681   IERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIG-ISKPSMPSRPFVP 739
             +E++   S  WM+ N     E  F    ++EG  YE RI A N  G IS PS  +   + 
Sbjct: 13813 VEKRDLPSKSWMKANHVNVPECAFTVTDLVEGGKYEFRIRAKNTAGAISAPSESTETIIC 13872

Query: 740   LAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDK 799
                   PT++   ++ D  +T++      + A  + G  L         W  A KD+   
Sbjct: 13873 KDEYEAPTIVLDPTIKD-GLTIKAGDTIVLNAISILGKPLP-----KSSWSKAGKDIRPS 13926

Query: 800   TKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRR 859
                 IT  PT + + ++      AG       + P   K            H+K T +  
Sbjct: 13927 DITQITSTPTSSMLTIKYATRKDAG-EYTITATNPFGTK----------VEHVKVTVLDV 13975

Query: 860   VGEAVNLVIPFQGKPRPELTWK---KDGAEIDKNQINIRNSETDTIIFIRKAERSHS--- 913
              G    + I      +  LTW    +DG    K+ I +   ET  +++   +E   S   
Sbjct: 13976 PGPPGPVEISNVSAEKATLTWTPPLEDGGSPIKSYI-LEKRETSRLLWTVVSEDIQSCRH 14034

Query: 914   --------GKYDLQVKV----DKFVETASIDIQIIDR---PGPPQIVKIEDVWGENVALT 958
                      +Y  +V       K     S  ++++DR   PGPP+  ++ +V      ++
Sbjct: 14035 VATKLIQGNEYIFRVSAVNHYGKGEPVQSEPVKMVDRFGPPGPPEKPEVSNVTKNTATVS 14094

Query: 959   WTPPKDDGNAAITGYTIQKADKKSMEWFTVIE-HYHRTSATITELVIGNEYYFRVFSENM 1017
             W  P DDG + ITGY +++ +KKS+ W   I+         +T L  G+ Y FRV +EN 
Sbjct: 14095 WKRPVDDGGSEITGYHVERREKKSLRWVRAIKTPVSDLRCKVTGLQEGSTYEFRVSAENR 14154

Query: 1018  CGL-----SEDATMTKESA 1031
              G+     + D+ + K++A
Sbjct: 14155 AGIGPPSEASDSVLMKDAA 14173



 Score =  116 bits (291), Expect = 1e-25
 Identities = 187/859 (21%), Positives = 324/859 (37%), Gaps = 143/859 (16%)

Query: 349   VTAGDEKCSTELFVREPPIMVTKQLEDT-TAYCGERVELECEV-SEDDANVKWFKNGEEI 406
             +TA DE       V  P I +  + +DT   + GE  +++ ++  +    ++W K  +E+
Sbjct: 16035 ITARDE-------VDPPRISMDPKYKDTIVVHAGESFKVDADIYGKPIPTIQWIKGDQEL 16087

Query: 407   IPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTD 466
                  +R  I+       L ++ A + D+  Y +          ++V++K L    P   
Sbjct: 16088 --SNTARLEIKSTDFATSLSVKDAVRVDSGNYILKAKNVAGERSVTVNVKVLDRPGPPEG 16145

Query: 467   QTVNLGKEICLKCEISENIPGKWTKNGLPVQE--SDRLKVVHKGR-----IHKLVIANAL 519
               V  G     KC ++      W     P+Q+  SD +  + + R     +  +V AN  
Sbjct: 16146 PVVISGVT-AEKCTLA------WKP---PLQDGGSDIINYIVERRETSRLVWTVVDANVQ 16195

Query: 520   TED-------EG-DYVF---APDAYNVTLPAKVH--VIDPPKIILDGLDADNTVTVIAGN 566
             T         EG +Y F   A + Y V  P +    V   P ++ D   A    TV   +
Sbjct: 16196 TLSCKVTKLLEGNEYTFRIMAVNKYGVGEPLESEPVVAKNPFVVPDAPKAPEVTTVTKDS 16255

Query: 567   KLRL-EIPISG------------EPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDI 613
              + + E P S                    W+R  K ++ G  R+R          V  +
Sbjct: 16256 MIVVWERPASDGGSEILGYVLEKRDKEGIRWTRCHKRLI-GELRLR----------VTGL 16304

Query: 614   AERDDSGVYHINLKNEAGEAHAS---IKVKVVD---FPDPPVAPTVTEVGDDWCIMNWEP 667
              E  D   + ++ +N AG +  S      K  D    P PP  P V ++      ++W  
Sbjct: 16305 IENHDYE-FRVSAENAAGLSEPSPPSAYQKACDPIYKPGPPNNPKVIDITRSSVFLSWSK 16363

Query: 668   PAYDGGSPILGYFIERKKKQSSRWMRLNFDL-CKETTFEPKKMIEGVAYEVRIFAVNAIG 726
             P YDGG  I GY +E+       W          +T  E +K++E   Y  RI A+N  G
Sbjct: 16364 PIYDGGCEIQGYIVEKCDVSVGEWTMCTPPTGINKTNIEVEKLLEKHEYNFRICAINKAG 16423

Query: 727   ISKPSMPSRPFVPLAVTSPPTL-----------LTVDSVTDTTVTMRWRPPDHIGAAGLD 775
             + + +    P +       P +           +         V ++ RP   +    +D
Sbjct: 16424 VGEHADVPGPIIVEEKLEAPDIDLDLELRKIINIRAGGSLRLFVPIKGRPTPEVKWGKVD 16483

Query: 776   GYVLEYCF----EGTEDWIVANKDLIDKTKFTIT--GLPTDAKIFVRVKAVNAAGASEPK 829
             G + +             ++ N +  D  K+T+T          FV V+ ++    S P 
Sbjct: 16484 GEIRDAAIIDVTSSFTSLVLDNVNRYDSGKYTLTLENSSGTKSAFVTVRVLDTP--SPPV 16541

Query: 830   YYSQPILVKEII----EPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGA 885
                   + K+ +    EPP +     +K   + +                 E T K   A
Sbjct: 16542 NLKVTEITKDSVSITWEPPLLDGGSKIKNYIVEK----------------REATRKSYAA 16585

Query: 886   EID---KNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPP 942
              +    KN   I   +     + R    +  G       +    +TA   I++ + P PP
Sbjct: 16586 VVTNCHKNSWKIDQLQEGCSYYFRVTAENEYG-------IGLPAQTAD-PIKVAEVPQPP 16637

Query: 943   QIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITEL 1002
               + ++DV   +V+L+WT P+ DG + I  Y ++   K S +W +         A IT L
Sbjct: 16638 GKITVDDVTRNSVSLSWTKPEHDGGSKIIQYIVEMQAKHSEKW-SECARVKSLQAVITNL 16696

Query: 1003  VIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVN 1062
               G EY FRV + N  G S+  ++     ++A+D  I  +               +P  +
Sbjct: 16697 TQGEEYLFRVVAVNEKGRSDPRSLAVP--IVAKDLVIEPD--------------VKPAFS 16740

Query: 1063  TYAI-AGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDG 1121
             +Y++  G +  +   + G PKP ITW K+ + +    R  +  +  + TL I++    DG
Sbjct: 16741 SYSVQVGQDLKIEVPISGRPKPTITWTKDGLPLKQTTRINVTDSLDLTTLSIKETHKDDG 16800

Query: 1122  GTYCCKAVNDLG--TVEIE 1138
             G Y     N +G  T  IE
Sbjct: 16801 GQYGITVANVVGQKTASIE 16819



 Score =  115 bits (287), Expect = 3e-25
 Identities = 101/370 (27%), Positives = 158/370 (42%), Gaps = 34/370 (9%)

Query: 291  KGGRVRFVVELAD-----------------PKLEVKWYKNGQEIRPSTKYIFEHKGCQRI 333
            +G  V FV EL D                   +E KWY N  E++ + KY    +  ++ 
Sbjct: 2217 EGAVVEFVKELQDIEVPESYSGELECIVSPENIEGKWYHNDVELKSNGKYTITSRRGRQN 2276

Query: 334  LFINNCQMTDDSEYYVTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSED 393
            L + +    D  EY      +K + +L ++  PI + + L D     G+ V+LE +VS +
Sbjct: 2277 LTVKDVTKEDQGEYSFVIDGKKTTCKLKMKPRPIAILQGLSDQKVCEGDIVQLEVKVSLE 2336

Query: 394  DANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSV 453
                 W K+G+E+   P  R  I ++ + H+L+IE  TK DA  YS        S    V
Sbjct: 2337 SVEGVWMKDGQEV--QPSDRVHIVIDKQSHMLLIEDMTKEDAGNYSFTIPALGLSTSGRV 2394

Query: 454  DLKPLKILTPLTDQTVNLGKEICLKCEIS--ENIPGKWTKNGLPVQESDRLKVVHKGRIH 511
             +  + ++TPL D  V  G +  L+C++S  +    KW  N   ++  DR++ + KG   
Sbjct: 2395 SVYSVDVITPLKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVKGTKQ 2454

Query: 512  KLVIANALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLE 571
            +LVI      DEG Y              V  I     I+ GL  D T T        +E
Sbjct: 2455 RLVINRTHASDEGPYKLIVGRVETNCNLSVEKIK----IIRGL-RDLTCTETQNVVFEVE 2509

Query: 572  IPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAG 631
            +  SG      +W+  DK I + S + + E++     L +    +DD G Y       AG
Sbjct: 2510 LSHSG---IDVLWNFKDKEI-KPSSKYKIEAHGKIYKLTVLNMMKDDEGKYTF----YAG 2561

Query: 632  EAHASIKVKV 641
            E   S K+ V
Sbjct: 2562 ENMTSGKLTV 2571



 Score =  115 bits (287), Expect = 3e-25
 Identities = 182/792 (22%), Positives = 302/792 (38%), Gaps = 105/792 (13%)

Query: 398   KWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKP 457
             KW  +G EI       Y +  +    +L I+   + D  EY +  +    S  ++V L  
Sbjct: 11046 KWTTDGSEI--KTDEHYTVETDNFSSVLTIKNCLRRDTGEYQITVSNAAGSKTVAVHLTV 11103

Query: 458   LKILTPLTDQTVNLG---KEICLKCEISENIPGKWTKNGLPVQESDRLK----VVHKGRI 510
             L +  P T     L    + + +  +  ++  G    N + V++ D  K    VV  G  
Sbjct: 11104 LDVPGPPTGPINILDVTPEHMTISWQPPKDDGGSPVINYI-VEKQDTRKDTWGVVSSGSS 11162

Query: 511   H-KLVIANALTEDEGDYVFAPDAYNV---------TLPAKVHVIDPPKIILDGLDADNTV 560
               KL I +   +   +YVF   A N          T     H   PP            V
Sbjct: 11163 KTKLKIPHL--QKGCEYVFRVRAENKIGVGPPLDSTPTVAKHKFSPPSP-----PGKPVV 11215

Query: 561   TVIAGNKLRLE--IPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERD- 617
             T I  N   +   +P S    P   +    + +     R+      D    V  + E + 
Sbjct: 11216 TDITENAATVSWTLPKSDGGSPITGYYMERREVTGKWVRVNKTPIADLKFRVTGLYEGNT 11275

Query: 618   -DSGVYHINLKNEAGEAHASIKVKV---VDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGG 673
              +  V+  NL   +  + +S  +K    +  P PP+ P + +   +   + W  P  DGG
Sbjct: 11276 YEFRVFAENLAGLSKPSPSSDPIKACRPIKPPGPPINPKLKDKSRETADLVWTKPLSDGG 11335

Query: 674   SPILGYFIERKKKQSSRWMRLNFD-LCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSM 732
             SPILGY +E +K  +++W R+N D L ++  F    +IEG  Y  RI A N +G  +P  
Sbjct: 11336 SPILGYVVECQKPGTAQWNRINKDELIRQCAFRVPGLIEGNEYRFRIKAANIVGEGEPRE 11395

Query: 733   PSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVA 792
              +   +   +  PP +  +D      +T+R      I  A + G       E    W   
Sbjct: 11396 LAESVIAKDILHPPEV-ELDVTCRDVITVRVGQTIRI-LARVKGRP-----EPDITWTKE 11448

Query: 793   NKDLI-DKTKFTITGLPTDAKIFVRVKAVNAAGASEPKY---------YSQPILVKEIIE 842
              K L+ +K    I  LP      V ++   A  A   KY         ++Q   +  +++
Sbjct: 11449 GKVLVREKRVDLIQDLPR-----VELQIKEAVRADHGKYIISAKNSSGHAQGSAIVNVLD 11503

Query: 843   PPKIRIPRHLKQTYIRRVG--------------EAVNLVIPFQGKPRPELTWKKDGAEID 888
              P     ++LK T + +                E  N ++ ++ KP  +  W    +++ 
Sbjct: 11504 RPGPC--QNLKVTNVTKENCTISWENPLDNGGSEITNFIVEYR-KPNQK-GWSIVASDVT 11559

Query: 889   KNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETAS--IDIQIIDRPGPPQIVK 946
             K  I       +   F   AE         +V V   +ET +  + I  IDRPG P+ + 
Sbjct: 11560 KRLIKANLLANNEYYFRVCAEN--------KVGVGPTIETKTPILAINPIDRPGEPENLH 11611

Query: 947   IEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGN 1006
             I D     V L W  P  DG +    Y +++  K S +W  V +   + +  + +  + N
Sbjct: 11612 IADKGKTFVYLKWRRPDYDGGSPNLSYHVERRLKGSDDWERVHKGSIKETHYMVDRCVEN 11671

Query: 1007  EYY-FRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYA 1065
             + Y FRV ++N  G S+   +  E  V+  D               + P+    L     
Sbjct: 11672 QIYEFRVQTKNEGGESD--WVKTEEVVVKED--------------LQKPVLDLKLSGVLT 11715

Query: 1066  I-AGYNATLNCSVRGNPKPKITWMKNKVA--IVDDPRYRMFSNQGVCTLEIRKPSPYDGG 1122
             + AG    L   VRG P P++ W K+K A  +   PR ++ +        + K    DGG
Sbjct: 11716 VKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKAKRSDGG 11775

Query: 1123  TYCCKAVNDLGT 1134
              Y   A N  G+
Sbjct: 11776 KYVVTATNTAGS 11787



 Score =  112 bits (280), Expect = 2e-24
 Identities = 102/419 (24%), Positives = 166/419 (39%), Gaps = 35/419 (8%)

Query: 744   SPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFT 803
             SP   L  D +   +V + WRPP   G A + GY+LE        W   +   +  T   
Sbjct: 23733 SPEGPLEYDDIQVRSVRVSWRPPADDGGADILGYILERREVPKAAWYTIDSR-VRGTSLV 23791

Query: 804   ITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEA 863
             + GL  + +   RV A N  G S+P    +P+  K  + PP+   P       +     +
Sbjct: 23792 VKGLKENVEYHFRVSAENQFGISKPLKSEEPVTPKTPLNPPE---PPSNPPEVLDVTKSS 23848

Query: 864   VNLVIPFQGKPRPELTWKKDGAEIDKNQIN----IRNSETD-TIIFIRKAERSHSGKYDL 918
             V+L      +P+ +   +  G  I++ + +    +R+++T  T             +Y  
Sbjct: 23849 VSLS---WSRPKDDGGSRVTGYYIERKETSTDKWVRHNKTQITTTMYTVTGLVPDAEYQF 23905

Query: 919   QVKVDKFV---ETASIDIQII-----DRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAI 970
             ++     V   ET+     ++     D+P  P  ++I  +  ++V L W  P+ DG   I
Sbjct: 23906 RIIAQNDVGLSETSPASEPVVCKDPFDKPSQPGELEILSISKDSVTLQWEKPECDGGKEI 23965

Query: 971   TGYTIQKADKKSMEWF-TVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKE 1029
              GY ++        W  +  E       TI  L+   EY FRVF+EN  GLS        
Sbjct: 23966 LGYWVEYRQSGDSAWKKSNKERIKDKQFTIGGLLEATEYEFRVFAENETGLSRPRRTAMS 24025

Query: 1030  SAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMK 1089
                    G              EAP   + + +     G  A L+C + G P P I W +
Sbjct: 24026 IKTKLTSG--------------EAPGIRKEMKDVTTKLGEAAQLSCQIVGRPLPDIKWYR 24071

Query: 1090  NKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVKVIAQ 1148
                 ++   +Y+M S+    TL +      D G Y C A N++G VE   KL ++   Q
Sbjct: 24072 FGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVGEVETSSKLLLQATPQ 24130



 Score =  111 bits (277), Expect = 4e-24
 Identities = 171/794 (21%), Positives = 305/794 (38%), Gaps = 96/794 (12%)

Query: 381   GERVELECEVSEDDA-NVKWFKNGEEIIPGPKSRYRIRVEGKKHI--LIIEGATKADAAE 437
             G  V+L   +S   A  ++W+K+ +E+    ++   + VE    +  ++I+ A + ++  
Sbjct: 20390 GTSVKLRAGISGKPAPTIEWYKDDKEL----QTNALVCVENTTDLASILIKDADRLNSGC 20445

Query: 438   YSVMTTGGQSSAKLSVDL----KPLKILTPLTDQTVNLGKEICLKCEISENIPGKWTKNG 493
             Y +       SA  ++ +    KP     P+  +TV   K   L    +++   K T   
Sbjct: 20446 YELKLRNAMGSASATIRVQILDKPGPPGGPIEFKTVTAEKITLLWRPPADDGGAKITHYI 20505

Query: 494   LPVQESDRLK-VVHKGRIHKLVIANALTEDEGDYVF---APDAYNVTLPAKVH-VIDPPK 548
             +  +E+ R+   +    + + +I         +Y+F   A + Y +  P +   V+    
Sbjct: 20506 VEKRETSRVVWSMVSEHLEECIITTTKIIKGNEYIFRVRAVNKYGIGEPLESDSVVAKNA 20565

Query: 549   IILDGLDADNTVTVIAGNKLRL----EIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYP 604
              +  G      VT I  N + +     I   G         + DK  + G  ++  E+  
Sbjct: 20566 FVTPGPPGIPEVTKITKNSMTVVWSRPIADGGSDISGYFLEKRDKKSL-GWFKVLKETIR 20624

Query: 605   DSSTLVIDIAERDDSGVYHINLKNEAGE---AHASIKVKVVDFPDPPVAPTVTEVGDDW- 660
             D+   V  + E  D   Y +   N AG+   +  S   K  D  DPP  P    + D   
Sbjct: 20625 DTRQKVTGLTENSDYQ-YRVCAVNAAGQGPFSEPSEFYKAADPIDPPGPPAKIRIADSTK 20683

Query: 661   --CIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNF-DLCKETTFEPKKMIEGVAYEV 717
                 + W  P YDGGS + GY +E ++ +   W  ++     + T +    +  GV Y  
Sbjct: 20684 SSITLGWSKPVYDGGSAVTGYVVEIRQGEEEEWTTVSTKGEVRTTEYVVSNLKPGVNYYF 20743

Query: 718   RIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGY 777
             R+ AVN  G  +P   + P     +   P +       D  V +R      I  AG D  
Sbjct: 20744 RVSAVNCAGQGEPIEMNEPVQAKDILEAPEI-------DLDVALR---TSVIAKAGEDVQ 20793

Query: 778   VLEYCFEG----TEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVN-----------A 822
             VL   F+G    T  W    K+L    +++I    TD+   + +  V             
Sbjct: 20794 VL-IPFKGRPPPTVTWRKDEKNLGSDARYSIEN--TDSSSLLTIPQVTRNDTGKYILTIE 20850

Query: 823   AGASEPKYYSQPILVKEIIEP---PKIRIPRHLKQTYIRRVGE---------AVNLVIPF 870
              G  EPK  S  + VK +  P    K+++ +H+ +  +  + +          +N VI  
Sbjct: 20851 NGVGEPK--SSTVSVKVLDTPAACQKLQV-KHVSRGTVTLLWDPPLIDGGSPIINYVI-- 20905

Query: 871   QGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETAS 930
             + +   + TW     +       + +    T  F R    +  G       + +  ET  
Sbjct: 20906 EKRDATKRTWSVVSHKCSSTSFKLIDLSEKTPFFFRVLAENEIG-------IGEPCETTE 20958

Query: 931   IDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIE 990
               ++  + P P + + ++D    +V L+WT P  DG + IT Y +++  K    W +   
Sbjct: 20959 -PVKAAEVPAPIRDLSMKDSTKTSVILSWTKPDFDGGSVITEYVVERKGKGEQTW-SHAG 21016

Query: 991   HYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDF 1050
                     +++L   +   FRVF++N  GLS+  T+          G I    V E    
Sbjct: 21017 ISKTCEIEVSQLKEQSVLEFRVFAKNEKGLSDPVTI----------GPI---TVKELIIT 21063

Query: 1051  SEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCT 1110
              E  +   P        G+N  L    +G PKP I+W+K+ + + +    R    +   T
Sbjct: 21064 PEVDLSDIPGAQVTVRIGHNVHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKIT 21123

Query: 1111  LEIRKPSPYDGGTY 1124
             L I+      GG Y
Sbjct: 21124 LSIKNAKKEHGGKY 21137



 Score =  110 bits (276), Expect = 6e-24
 Identities = 178/826 (21%), Positives = 314/826 (38%), Gaps = 118/826 (14%)

Query: 377   TAYCGERVELECEVS-EDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADA 435
             T   G  + L+  V  + +  + W K  +E+    K    ++  GK+   +I+   ++D+
Sbjct: 22561 TIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDLCEK--VSLQYTGKRATAVIKFCDRSDS 22618

Query: 436   AEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCEISENIP-----GKWT 490
              +Y++       +  +SV +K L    P    TV+   +   KC ++ ++P      + T
Sbjct: 22619 GKYTLTVKNASGTKAVSVMVKVLDSPGPCGKLTVSRVTQE--KCTLAWSLPQEDGGAEIT 22676

Query: 491   KNGLPVQESDRLK-VVHKGRIHKLVIANALTEDEGDYVF---APDAYNVTLPAKVH---- 542
                +  +E+ RL  V+ +G    L           +Y+F   A + Y   +P +      
Sbjct: 22677 HYIVERRETSRLNWVIVEGECPTLSYVVTRLIKNNEYIFRVRAVNKYGPGVPVESEPIVA 22736

Query: 543   ----VIDPPKIILDGLDADNTVTVI--------AGNKLRLEIPISGEPPPKAMWSRGDKA 590
                  I  P  I + +       +I         GN++   + +         W+R +K 
Sbjct: 22737 RNSFTIPSPPGIPEEVGTGKEHIIIQWTKPESDGGNEISNYL-VDKREKKSLRWTRVNKD 22795

Query: 591   IMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDF-PDPPV 649
              +    R++  S  +       +   + +G       +E  EA   I  +   + P PP 
Sbjct: 22796 YVVYDTRLKVTSLMEGCDYQFRVTAVNAAG------NSEPSEASNFISCREPSYTPGPPS 22849

Query: 650   APTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLC-KETTFEPKK 708
             AP V +       + W  P YDGG+ I+GY +E ++K + +W R++ +   + T F    
Sbjct: 22850 APRVVDTTKHSISLAWTKPMYDGGTDIVGYVLEMQEKDTDQWYRVHTNATIRNTEFTVPD 22909

Query: 709   MIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTT---------- 758
             +  G  Y  R+ AVN  G+S+ S       P+     P L   D +  T           
Sbjct: 22910 LKMGQKYSFRVAAVNVKGMSEYSESIAEIEPVERIEIPDLELADDLKKTVTIRAGASLRL 22969

Query: 759   -VTMRWRPPDHI--GAAGLDGYVLEYCFEGTEDW---IVANKDLIDKTKFTITGLPTDAK 812
              V++  RPP  I     G+D        + TE +   IV   +  D  K+TI        
Sbjct: 22970 MVSVSGRPPPVITWSKQGID-LASRAIIDTTESYSLLIVDKVNRYDAGKYTI-------- 23020

Query: 813   IFVRVKAVNAAGASEPKYYSQPILVKEIIEP---PKIRIPRHLKQTY-----IRRV--GE 862
                  +A N +G       S  +LVK    P   P +++    + +      I  +  G 
Sbjct: 23021 -----EAENQSGKK-----SATVLVKVYDTPGPCPSVKVKEVSRDSVTITWEIPTIDGGA 23070

Query: 863   AVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKV 922
              VN  I  + +      +K    +  K    I      T+ + R    +  G       +
Sbjct: 23071 PVNNYI-VEKREAAMRAFKTVTTKCSKTLYRISGLVEGTMYYFRVLPENIYG-------I 23122

Query: 923   DKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKS 982
              +  ET+   + + + P  P  +++ DV    V L W  P  DG + +TGY ++     +
Sbjct: 23123 GEPCETSDA-VLVSEVPLVPAKLEVVDVTKSTVTLAWEKPLYDGGSRLTGYVLEACKAGT 23181

Query: 983   MEWF-------TVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIAR 1035
               W        TV+EH      T+T L  G +Y FR+ ++N  G+SE       +AV  +
Sbjct: 23182 ERWMKVVTLKPTVLEH------TVTSLNEGEQYLFRIRAQNEKGVSEPRETV--TAVTVQ 23233

Query: 1036  DGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIV 1095
             D ++         D S     T P    +  AG    L   + G P P  +W      + 
Sbjct: 23234 DLRVLPT-----IDLS-----TMPQKTIHVPAGRPVELVIPIAGRPPPAASWFFAGSKLR 23283

Query: 1096  DDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKL 1141
             +  R  + ++  V  L IR+ +  D G Y  +  N  GT     K+
Sbjct: 23284 ESERVTVETHTKVAKLTIRETTIRDTGEYTLELKNVTGTTSETIKV 23329



 Score =  110 bits (275), Expect = 8e-24
 Identities = 108/438 (24%), Positives = 170/438 (38%), Gaps = 62/438 (14%)

Query: 727   ISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGT 786
             + KP +P+ P            +  D VT   +T++W PP   G + +  Y+LE      
Sbjct: 13576 VGKPGIPTGP------------IKFDEVTAEAMTLKWAPPKDDGGSEITNYILEKRDSVN 13623

Query: 787   EDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGA-----SEPKYYSQPILVKEII 841
               W+      + KT F +T L    +   RV A N  G      SEP     P  V +  
Sbjct: 13624 NKWVTC-ASAVQKTTFRVTRLHEGMEYTFRVSAENKYGVGEGLKSEPIVARHPFDVPDAP 13682

Query: 842   EPPKIRIPRH----LKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNS 897
              PP I   RH    L  T  ++ G +       + K R  L WK+     +K  I +R+ 
Sbjct: 13683 PPPNIVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKR----ANKTPIRMRDF 13738

Query: 898   ETDTIIFIRKAERSHSGKYDLQVKVDKFVETAS--------IDIQIIDRPGPPQIVKIED 949
             +   +        +   +Y+ +V                  + +  ID PG P+++ I  
Sbjct: 13739 KVTGL--------TEGLEYEFRVMAINLAGVGKPSLPSEPVVALDPIDPPGKPEVINITR 13790

Query: 950   VWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIE-HYHRTSATITELVIGNEY 1008
                 +V L WT PK DG   +TGY ++K D  S  W      +    + T+T+LV G +Y
Sbjct: 13791 ---NSVTLIWTEPKYDGGHKLTGYIVEKRDLPSKSWMKANHVNVPECAFTVTDLVEGGKY 13847

Query: 1009  YFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAI-- 1066
              FR+ ++N  G     + + E+ +I +D            ++    +   P +       
Sbjct: 13848 EFRIRAKNTAGAISAPSESTET-IICKD------------EYEAPTIVLDPTIKDGLTIK 13894

Query: 1067  AGYNATLNC-SVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYC 1125
             AG    LN  S+ G P PK +W K    I      ++ S      L I+  +  D G Y 
Sbjct: 13895 AGDTIVLNAISILGKPLPKSSWSKAGKDIRPSDITQITSTPTSSMLTIKYATRKDAGEYT 13954

Query: 1126  CKAVNDLGTVEIECKLEV 1143
               A N  GT     K+ V
Sbjct: 13955 ITATNPFGTKVEHVKVTV 13972



 Score =  109 bits (273), Expect = 1e-23
 Identities = 118/440 (26%), Positives = 185/440 (42%), Gaps = 69/440 (15%)

Query: 622   YHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFI 681
             Y +N    +  + AS  +   +  D P  P VT+V      + W  PAYDGGS ++GY I
Sbjct: 22419 YALNAAGVSKASEASRPIMAQNPVDAPGRPEVTDVTRSTVSLIWSAPAYDGGSKVVGYII 22478

Query: 682   ERK---KKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIG-ISKPSMPSRPF 737
             ERK   +    RW++ N+ +  +  F    + EG  YE R+ A NA G ISK S  + P 
Sbjct: 22479 ERKPVSEVGDGRWLKCNYTIVSDNFFTVTALSEGDTYEFRVLAKNAAGVISKGSESTGPV 22538

Query: 738   VPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTED----WIVAN 793
                   +PP       +    VT+R         AG D  VL+    G  +    W   +
Sbjct: 22539 TCRDEYAPPKAELDARLHGDLVTIR---------AGSD-LVLDAAVGGKPEPKIIWTKGD 22588

Query: 794   K--DLIDKTKFTITGLPTDAKIFVRVKA------VNAAGASEPKYYSQPILVKEIIEPPK 845
             K  DL +K     TG    A I    ++      +    AS  K  S  ++VK +  P  
Sbjct: 22589 KELDLCEKVSLQYTGKRATAVIKFCDRSDSGKYTLTVKNASGTKAVS--VMVKVLDSP-- 22644

Query: 846   IRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTW----KKDGAEI--------DKNQIN 893
                            G    L +    + +  L W    +  GAEI        + +++N
Sbjct: 22645 ---------------GPCGKLTVSRVTQEKCTLAWSLPQEDGGAEITHYIVERRETSRLN 22689

Query: 894   --IRNSETDTIIFIRKAERSHSGKYDLQVK-VDKFVETASIDIQ-IIDR-----PGPPQI 944
               I   E  T+ ++       + +Y  +V+ V+K+     ++ + I+ R     P PP I
Sbjct: 22690 WVIVEGECPTLSYV-VTRLIKNNEYIFRVRAVNKYGPGVPVESEPIVARNSFTIPSPPGI 22748

Query: 945   VKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHY--HRTSATITEL 1002
              +      E++ + WT P+ DG   I+ Y + K +KKS+ W  V + Y  + T   +T L
Sbjct: 22749 PEEVGTGKEHIIIQWTKPESDGGNEISNYLVDKREKKSLRWTRVNKDYVVYDTRLKVTSL 22808

Query: 1003  VIGNEYYFRVFSENMCGLSE 1022
             + G +Y FRV + N  G SE
Sbjct: 22809 MEGCDYQFRVTAVNAAGNSE 22828



 Score =  109 bits (272), Expect = 2e-23
 Identities = 92/363 (25%), Positives = 161/363 (44%), Gaps = 18/363 (4%)

Query: 294  RVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGD 353
            R  F  E+++P + V+W K+ QE++ + +   + +     L I + +M+D  +Y V AG 
Sbjct: 3028 RAMFECEVSEPDITVQWMKDDQELQITDRIKIQKEKYVHRLLIPSTRMSDAGKYTVVAGG 3087

Query: 354  EKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSR 413
               + +LFV    + +    ++      +R  +E EV+EDD +  W+K+G EI    + R
Sbjct: 3088 NVSTAKLFVEGRDVRIRSIKKEVQVIEKQRAVVEFEVNEDDVDAHWYKDGIEINFQVQER 3147

Query: 414  YRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDL-KPLKILTPLTDQTVNLG 472
            ++  VE + H + I    ++DA EY+ +    +SS  L V+  +P ++L  L   TV  G
Sbjct: 3148 HKYVVERRIHRMFISETRQSDAGEYTFVAGRNRSSVTLYVNAPEPPQVLQELQPVTVQSG 3207

Query: 473  KEICLKCEISENIPGK--WTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVF-A 529
            K       IS     K  W K    +    + K +H G+ + L++  A  ED   Y   A
Sbjct: 3208 KPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEA 3267

Query: 530  PDAYNVTLPAKVHVIDPPKIILDGLD-----------ADNTVTVIAGNKLRLEIPISGEP 578
             + Y V   +    ++ P+++    +             +TVT   G   R +  +SG  
Sbjct: 3268 KNDYGVATTSASLSVEVPEVVSPDQEMPVYPPAIITPLQDTVT-SEGQPARFQCRVSG-T 3325

Query: 579  PPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIK 638
              K  W   DK I + S   R   + D+  L I  A  +D G Y     N  G+  ++  
Sbjct: 3326 DLKVSWYSKDKKI-KPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTAN 3384

Query: 639  VKV 641
            + +
Sbjct: 3385 LSL 3387



 Score =  107 bits (268), Expect = 5e-23
 Identities = 123/468 (26%), Positives = 198/468 (42%), Gaps = 56/468 (11%)

Query: 221  RREVKQQEEE---PQVDVWELLKNAKPSEYEKIAFQYGITDLRGMLKRLKRMRREEKKSA 277
            R + K++ EE     +   EL    K   YE++  +        +L   K +  EEKK+ 
Sbjct: 1952 RSKFKRRTEEGYYEAITAVELKSRKKDESYEELLRK----TKDELLHWTKELTEEEKKAL 2007

Query: 278  AF-AKILDPAYQVDK-----------------------GGRVRFVVELAD-PKLEVKWYK 312
            A   KI  P ++ DK                       G    F V +   P  E +WYK
Sbjct: 2008 AEEGKITIPTFKPDKIELSPSMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYK 2067

Query: 313  NGQEIRPSTK---YIFEHKGCQRILFINNCQMTDDSEYYV----TAGDEKCSTELFVREP 365
            NG +I  S +   Y  E   C+  L I +    D +   V     AG+      L V+  
Sbjct: 2068 NGVKIERSDRIYWYWPEDNVCE--LVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQAK 2125

Query: 366  PIMV-TKQLEDTTAYCGERV-ELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKH 423
             ++  T++L+D  A   + +   ECE SE    VKW+K+G E+  G K  YR+  + K H
Sbjct: 2126 QLITFTQELQDVVAKEKDTMATFECETSEPFVKVKWYKDGMEVHEGDK--YRMHSDRKVH 2183

Query: 424  ILIIEGATKADAAEYS---VMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCE 480
             L I     +DA +YS   V     +++AKL V+   ++ +  L D  V       L+C 
Sbjct: 2184 FLSILTIDTSDAEDYSCVLVEDENVKTTAKLIVEGAVVEFVKELQDIEVPESYSGELECI 2243

Query: 481  IS-ENIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPA 539
            +S ENI GKW  N + ++ + +  +  +     L + +   ED+G+Y F  D    T   
Sbjct: 2244 VSPENIEGKWYHNDVELKSNGKYTITSRRGRQNLTVKDVTKEDQGEYSFVIDGKKTT--C 2301

Query: 540  KVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIR 599
            K+ +   P  IL GL       V  G+ ++LE+ +S E   + +W + D   ++ S R+ 
Sbjct: 2302 KLKMKPRPIAILQGLSDQK---VCEGDIVQLEVKVSLE-SVEGVWMK-DGQEVQPSDRVH 2356

Query: 600  TESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDP 647
                  S  L+I+   ++D+G Y   +          + V  VD   P
Sbjct: 2357 IVIDKQSHMLLIEDMTKEDAGNYSFTIPALGLSTSGRVSVYSVDVITP 2404



 Score =  106 bits (265), Expect = 1e-22
 Identities = 127/538 (23%), Positives = 203/538 (37%), Gaps = 68/538 (12%)

Query: 645  PDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTF 704
            P PP  P V +       + W+PPA DGGSPI GY +E +++ ++ W R+N      TT 
Sbjct: 9208 PGPPSCPEVKDKTKSSISLGWKPPAKDGGSPIKGYIVEMQEEGTTDWKRVNEPDKLITTC 9267

Query: 705  E--PKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTV--- 759
            E     + E   Y  R+ AVN  G S+PS  +       +   P +       D  V   
Sbjct: 9268 ECVVPNLKELRKYRFRVKAVNEAGESEPSDTTGEIPATDIQEEPEVFIDIGAQDCLVCKA 9327

Query: 760  --------TMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDA 811
                     ++ RP     +   DG   +   +G  D I  +  L      ++  +P   
Sbjct: 9328 GSQIRIPAVIKGRPTPK-SSWEFDGKAKKAMKDGVHD-IPEDAQLETAENSSVIIIPECK 9385

Query: 812  KIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIP-- 869
            +      ++ A   +  K  +  + V ++  PPK      LK + I R    ++  +P  
Sbjct: 9386 RSHTGKYSITAKNKAGQKTANCRVKVMDVPGPPK-----DLKVSDITRGSCRLSWKMPDD 9440

Query: 870  ----------FQGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIR-KAERSHSGKYDL 918
                       + +      W K   +       + +  ++   F R +AE     ++ +
Sbjct: 9441 DGGDRIKGYVIEKRTIDGKAWTKVNPDCGSTTFVVPDLLSEQQYFFRVRAEN----RFGI 9496

Query: 919  QVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQ-- 976
               V+    T + D   I  P PP  +KI  +    V L+W PPK+DG + +T Y ++  
Sbjct: 9497 GPPVETIQRTTARDP--IYPPDPPIKLKIGLITKNTVHLSWKPPKNDGGSPVTHYIVECL 9554

Query: 977  ---KADKKSMEWFTVIEH-YHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAV 1032
                   K   W    +        T+ +LV G EY FRV + N  G+S+ +        
Sbjct: 9555 AWDPTGTKKEAWRQCNKRDVEELQFTVEDLVEGGEYEFRVKAVNAAGVSKPSATVGPCDC 9614

Query: 1033 IARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMK--- 1089
               D      P  +  +F E               G N  +   ++G P P +TW K   
Sbjct: 9615 QRPD----MPPSIDLKEFMEVE------------EGTNVNIVAKIKGVPFPTLTWFKAPP 9658

Query: 1090 ----NKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1143
                NK  ++ D           CTL I +    D G Y   AVN+LGT   E +L V
Sbjct: 9659 KKPDNKEPVLYDTHVNKLVVDDTCTLVIPQSRRSDTGLYTITAVNNLGTASKEMRLNV 9716



 Score =  105 bits (263), Expect = 2e-22
 Identities = 101/375 (26%), Positives = 158/375 (42%), Gaps = 21/375 (5%)

Query: 288  QVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEY 347
            +V +G  V+  V+++   +E  W K+GQE++PS +          +L I +    D   Y
Sbjct: 2320 KVCEGDIVQLEVKVSLESVEGVWMKDGQEVQPSDRVHIVIDKQSHMLLIEDMTKEDAGNY 2379

Query: 348  YVTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDD-ANVKWFKNGEEI 406
              T      ST   V    + V   L+D     G +  LEC+VS  D  +VKW+ N E+I
Sbjct: 2380 SFTIPALGLSTSGRVSVYSVDVITPLKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQI 2439

Query: 407  IPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTD 466
               P  R +  V+G K  L+I     +D   Y ++    +++  LSV+   +KI+  L D
Sbjct: 2440 --KPDDRVQAIVKGTKQRLVINRTHASDEGPYKLIVGRVETNCNLSVE--KIKIIRGLRD 2495

Query: 467  QTVNLGKEICLKCEISEN-IPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGD 525
             T    + +  + E+S + I   W      ++ S + K+   G+I+KL + N + +DEG 
Sbjct: 2496 LTCTETQNVVFEVELSHSGIDVLWNFKDKEIKPSSKYKIEAHGKIYKLTVLNMMKDDEGK 2555

Query: 526  YVF--APDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAM 583
            Y F    +  +  L      I  P         D TV          E+     P  K  
Sbjct: 2556 YTFYAGENMTSGKLTVAGGAISKPL-------TDQTVAESQEAVFECEV---ANPDSKGE 2605

Query: 584  WSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVD 643
            W R  K  +  +  IR+ES      L+I   + DD G Y    K    +  A +KV+ V 
Sbjct: 2606 WLRDGKH-LPLTNNIRSESDGHKRRLIIAATKLDDIGEY--TYKVATSKTSAKLKVEAVK 2662

Query: 644  FPDPPVAPTVTEVGD 658
                    TVTE  D
Sbjct: 2663 IKKTLKNLTVTETQD 2677



 Score =  102 bits (255), Expect = 2e-21
 Identities = 103/389 (26%), Positives = 171/389 (43%), Gaps = 15/389 (3%)

Query: 273  EKKSAAFAKILDPAYQVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHK-GCQ 331
            E+    F K L+    V KG  +    EL + + +V W K+G+ +      I     G  
Sbjct: 4711 EELPVRFVKTLEEEVTVVKGQPLYLSCEL-NKERDVVWRKDGKIVVEKPGRIVPGVIGLM 4769

Query: 332  RILFINNCQMTDDSEYYVT---AGDEKCSTELFVREP-PIMVTKQLEDTTAYCGERVELE 387
            R L IN+   TD   Y VT   A + +CS+ + V E     + K + D            
Sbjct: 4770 RALTINDADDTDAGTYTVTVENANNLECSSCVKVVEVIRDWLVKPIRDQHVKPKGTAIFA 4829

Query: 388  CEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQS 447
            C++++D  N+KWFK  +EI   P  +  I  +G    L I+ A   D AEY+V   G + 
Sbjct: 4830 CDIAKDTPNIKWFKGYDEIPAEPNDKTEILRDGNHLYLKIKNAMPEDIAEYAVEIEGKRY 4889

Query: 448  SAKLSVDLKPLKILTPLTDQTVNLGKEICLKCEISE-NIPGKWTKNGLPVQESDRLKVVH 506
             AKL++  + +++L P+ D T+   +      EISE +IPG+W   G  ++ S   ++  
Sbjct: 4890 PAKLTLGEREVELLKPIEDVTIYEKESASFDAEISEADIPGQWKLKGELLRPSPTCEIKA 4949

Query: 507  KGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGN 566
            +G    L +     +  G+ ++   A N    A   ++   +I LD       VTV    
Sbjct: 4950 EGGKRFLTLHKVKLDQAGEVLY--QALNAITTA---ILTVKEIELDFAVPLKDVTVPERR 5004

Query: 567  KLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINL 626
            + R E  ++ E     +WS+G   I++ S +    +      LVI+ ++ DD GVY   +
Sbjct: 5005 QARFECVLTRE--ANVIWSKGPD-IIKSSDKFDIIADGKKHILVINDSQFDDEGVYTAEV 5061

Query: 627  KNEAGEAHASIKVKVVDFPDPPVAPTVTE 655
            + +   A   +    + F  P    TV E
Sbjct: 5062 EGKKTSARLFVTGIRLKFMSPLEDQTVKE 5090



 Score =  102 bits (254), Expect = 2e-21
 Identities = 85/281 (30%), Positives = 121/281 (43%), Gaps = 16/281 (5%)

Query: 308  VKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTELFVREPPI 367
            V W K    I+ S K+     G + IL IN+ Q  D+  Y      +K S  LFV    +
Sbjct: 5018 VIWSKGPDIIKSSDKFDIIADGKKHILVINDSQFDDEGVYTAEVEGKKTSARLFVTGIRL 5077

Query: 368  MVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILII 427
                 LED T   GE     CE+S +  +V WFKN  ++         I  EGK H L +
Sbjct: 5078 KFMSPLEDQTVKEGETATFVCELSHEKMHVVWFKNDAKL--HTSRTVLISSEGKTHKLEM 5135

Query: 428  EGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCEISENIPG 487
            +  T  D ++         S+A+L V          L D+T     EI LKCE+S+++P 
Sbjct: 5136 KEVTLDDISQIKAQVKELSSTAQLKVLEADPYFTVKLHDKTAVEKDEITLKCEVSKDVPV 5195

Query: 488  KWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYV----FAPDAYNVTLPAKVHV 543
            KW K+G  +  S +  +   G    L I  A  +D+G+YV          NVT+ A++  
Sbjct: 5196 KWFKDGEEIVPSPKYSIKADGLRRILKIKKADLKDKGEYVCDCGTDKTKANVTVEARLIK 5255

Query: 544  IDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMW 584
            ++ P   L G      V V  G     EI +S EP     W
Sbjct: 5256 VEKP---LYG------VEVFVGETAHFEIELS-EPDVHGQW 5286



 Score =  102 bits (254), Expect = 2e-21
 Identities = 174/746 (23%), Positives = 285/746 (38%), Gaps = 121/746 (16%)

Query: 365   PPIMVTKQLEDTTAYCGERVELECEV-SEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKH 423
             P I++ +Q+   T   G+++ +E  V  +     KW K  +E++    S   +       
Sbjct: 12403 PKILMPEQI---TIKAGKKLRIEAHVYGKPHPTCKWKKGEDEVVTS--SHLAVHKADSSS 12457

Query: 424   ILIIEGATKADAAEYSVMT--TGGQSSAKLSV--------------------DLKPLKIL 461
             ILII+  T+ D+  YS+    + G  + K+ V                    D   L   
Sbjct: 12458 ILIIKDVTRKDSGYYSLTAENSSGTDTQKIKVVVMDAPGPPQPPFDISDIDADACSLSWH 12517

Query: 462   TPLTDQTVNLGKEICLKCEISENIPGKW-TKNGLPVQESDRLKVVHKGRIH--------K 512
              PL D   N+   I  KC++S    G W T      + S R+  +  G+ +        +
Sbjct: 12518 IPLEDGGSNITNYIVEKCDVSR---GDWVTALASVTKTSCRVGKLIPGQEYIFRVRAENR 12574

Query: 513   LVIANALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKIIL--DGLDADNTVTVIAGNKLRL 570
               I+  LT  +    F     +    A+V  ++   I +  D  D+D    +I       
Sbjct: 12575 FGISEPLTSPKMVAQFPFGVPSEPKNARVTKVNKDCIFVAWDRPDSDGGSPIIG------ 12628

Query: 571   EIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEA 630
                I  +     +W + +  +      +R+  YP +   +++  E      + I   N+A
Sbjct: 12629 -YLIERKERNSLLWVKANDTL------VRSTEYPCAG--LVEGLEYS----FRIYALNKA 12675

Query: 631   GEAHASIKVKVVDFP---DPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQ 687
             G +  S   + V      DPP  P V +V      + W  P +DGGS I+GYF+E  K  
Sbjct: 12676 GSSPPSKPTEYVTARMPVDPPGKPEVIDVTKSTVSLIWARPKHDGGSKIIGYFVEACKLP 12735

Query: 688   SSRWMRLNF--DLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSP 745
               +W+R N       +  +    + E   Y+ R  A  A+ IS PS PS P   LA   P
Sbjct: 12736 GDKWVRCNTAPHQIPQEEYTATGLEEKAQYQFRAIARTAVNISPPSEPSDPVTILAENVP 12795

Query: 746   P---------TLLTVDSVT----DTTV------TMRWRPPDHI--GAAGLDGYVLEYCFE 784
             P         +LLTV + T    D TV      T+ W+    +   A G+    ++    
Sbjct: 12796 PRIDLSVAMKSLLTVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIK-MAMQRNLC 12854

Query: 785   GTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEP----KYYSQPILVKEI 840
               E + V  KD  D T  T           +++K ++  G        K YS   ++   
Sbjct: 12855 TLELFSVNRKDSGDYT-ITAENSSGSKSATIKLKVLDKPGPPASVKINKMYSDRAMLSW- 12912

Query: 841   IEPPKIRIPRHLKQTYIRRVG-EAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSET 899
              EPP            +   G E  N ++  +   RP   W +  A +     ++     
Sbjct: 12913 -EPP------------LEDGGSEITNYIVDKRETSRPN--WAQVSATVPITSCSVEKLIE 12957

Query: 900   DTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTW 959
                   R    +  G  D       F E A I     D PG      I ++  +++ ++W
Sbjct: 12958 GHEYQFRICAENKYGVGD-----PVFTEPA-IAKNPYDPPGRCDPPVISNITKDHMTVSW 13011

Query: 960   TPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATI--TELVIGNEYYFRVFSENM 1017
              PP DDG + ITGY ++K + +++ W T +        T+  T L  G EY FRV + N 
Sbjct: 13012 KPPADDGGSPITGYLLEKRETQAVNW-TKVNRKPIIERTLKATGLQEGTEYEFRVTAINK 13070

Query: 1018  CGLSEDATMTKESAVIARDGKIYKNP 1043
              G  + +  +K  A  ARD +    P
Sbjct: 13071 AGPGKPSDASK--AAYARDPQYPPGP 13094



 Score =  101 bits (251), Expect = 5e-21
 Identities = 123/553 (22%), Positives = 204/553 (36%), Gaps = 63/553 (11%)

Query: 622   YHINLKNEAGEAHASIKVKVV---DFPDPPVAPTVTEVGDDW---CIMNWEPPAYDGGSP 675
             + +  +NE G    S+  + V   D  +PP  PT   V D       + W  P YDGG+P
Sbjct: 11971 FRVKAENEIGIGEPSLPSRPVVAKDPIEPPGPPTNFRVVDTTKHSITLGWGKPVYDGGAP 12030

Query: 676   ILGYFIERKKKQSSR-----WMRLNFDL-CKETTFEPKKMIEGVAYEVRIFAVNAIGISK 729
             I+GY +E + K +       W R N         F    + E   YE R+ A N +GI +
Sbjct: 12031 IIGYVVEMRPKIADASPDEGWKRCNAAAQLVRKEFTVTSLDENQEYEFRVCAQNQVGIGR 12090

Query: 730   PSMPSRPFVPLAVTSPPTLLTVDSVTDTTVT-----------MRWRPPDHIG--AAGLDG 776
             P+       P  +  PP +    S+    +            +R RP   +     G+D 
Sbjct: 12091 PAELKEAIKPKEILEPPEIDLDASMRKLVIVRAGCPIRLFAIVRGRPAPKVTWRKVGIDN 12150

Query: 777   YVLEYCFEGTEDW---IVANKDLIDKTKFTITGL-PTDAK-IFVRVKAVNAAGASEPKYY 831
              V +   +  +     ++ N    D  K+++T + P   K +FV V+ ++  G       
Sbjct: 12151 VVRKGQVDLVDTMAFLVIPNSTRDDSGKYSLTLVNPAGEKAVFVNVRVLDTPG------- 12203

Query: 832   SQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQ 891
               P+   ++ +  K     H+        G +       + +     TW     E+ K  
Sbjct: 12204 --PVSDLKVSDVTKTSC--HVSWAPPENDGGSQVTHYIVEKREADRKTWSTVTPEVKKTS 12259

Query: 892   INIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVW 951
              ++ N       + R    +  G       V   V    +    +  P PP+ +++ ++ 
Sbjct: 12260 FHVTNLVPGNEYYFRVTAVNEYGP-----GVPTDVPKPVLASDPLSEPDPPRKLEVTEMT 12314

Query: 952   GENVALTWTPPKDDGNAAITGY-TIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYF 1010
               +  L W PP  DG A I GY T  + +++  + +T        S  +T L  G +Y F
Sbjct: 12315 KNSATLAWLPPLRDGGAKIDGYITSYREEEQPADRWTEYSVVKDLSLVVTGLKEGKKYKF 12374

Query: 1011  RVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYN 1070
             RV + N  G+S           + R+ +     VYE  +    P    P   T   AG  
Sbjct: 12375 RVAARNAVGVS-----------LPREAE----GVYEAKEQLLPPKILMPEQITIK-AGKK 12418

Query: 1071  ATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVN 1130
               +   V G P P   W K +  +V      +        L I+  +  D G Y   A N
Sbjct: 12419 LRIEAHVYGKPHPTCKWKKGEDEVVTSSHLAVHKADSSSILIIKDVTRKDSGYYSLTAEN 12478

Query: 1131  DLGTVEIECKLEV 1143
               GT   + K+ V
Sbjct: 12479 SSGTDTQKIKVVV 12491



 Score =  100 bits (249), Expect = 8e-21
 Identities = 93/398 (23%), Positives = 157/398 (39%), Gaps = 40/398 (10%)

Query: 753   SVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAK 812
             +VT   +T+ WRPP   G A +  Y++E        W + ++ L ++   T T +    +
Sbjct: 20480 TVTAEKITLLWRPPADDGGAKITHYIVEKRETSRVVWSMVSEHL-EECIITTTKIIKGNE 20538

Query: 813   IFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQT-------YIRRVGEAVN 865
                RV+AVN  G  EP      +     + P    IP   K T       + R + +  +
Sbjct: 20539 YIFRVRAVNKYGIGEPLESDSVVAKNAFVTPGPPGIPEVTKITKNSMTVVWSRPIADGGS 20598

Query: 866   LVIPF--QGKPRPELTW---KKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQV 920
              +  +  + + +  L W    K+     + ++      +D    +     +  G +    
Sbjct: 20599 DISGYFLEKRDKKSLGWFKVLKETIRDTRQKVTGLTENSDYQYRVCAVNAAGQGPFS--- 20655

Query: 921   KVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADK 980
             +  +F + A      ID PGPP  ++I D    ++ L W+ P  DG +A+TGY ++    
Sbjct: 20656 EPSEFYKAADP----IDPPGPPAKIRIADSTKSSITLGWSKPVYDGGSAVTGYVVEIRQG 20711

Query: 981   KSMEWFTVIE--HYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGK 1038
             +  EW TV        T   ++ L  G  YYFRV + N  G  E   M            
Sbjct: 20712 EEEEWTTVSTKGEVRTTEYVVSNLKPGVNYYFRVSAVNCAGQGEPIEM------------ 20759

Query: 1039  IYKNPVYEDFDFSEAPMFTQPLV---NTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIV 1095
                N   +  D  EAP     +    +  A AG +  +    +G P P +TW K++  + 
Sbjct: 20760 ---NEPVQAKDILEAPEIDLDVALRTSVIAKAGEDVQVLIPFKGRPPPTVTWRKDEKNLG 20816

Query: 1096  DDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLG 1133
              D RY + +      L I + +  D G Y     N +G
Sbjct: 20817 SDARYSIENTDSSSLLTIPQVTRNDTGKYILTIENGVG 20854



 Score = 98.6 bits (244), Expect = 3e-20
 Identities = 93/361 (25%), Positives = 149/361 (41%), Gaps = 12/361 (3%)

Query: 296  RFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEK 355
            +F  E++      +W K  QEI    ++     G +  + I +    D+++Y   A D+ 
Sbjct: 5361 KFECEVSREPKTFRWLKGTQEITGDDRFELIKDGTKHSMVIKSAAFEDEAKYMFEAEDKH 5420

Query: 356  CSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYR 415
             S +L +    +     L+D TA   E      E+S D+  VKWFKN + +         
Sbjct: 5421 TSGKLIIEGIRLKFLTPLKDVTAKEKESAVFTVELSHDNIRVKWFKNDQRL--HTTRSVS 5478

Query: 416  IRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEI 475
            ++ EGK H +  +  +  D ++  V   G  S AKL+V          L D T     E+
Sbjct: 5479 MQDEGKTHSITFKDLSIDDTSQIRVEAMGMSSEAKLTVLEGDPYFTGKLQDYTGVEKDEV 5538

Query: 476  CLKCEISE-NIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYN 534
             L+CEIS+ + P KW K+G  ++ S    +   G+   L++  AL  D G Y    D   
Sbjct: 5539 ILQCEISKADAPVKWFKDGKEIKPSKNAVIKADGKKRMLILKKALKSDIGQYTC--DCGT 5596

Query: 535  VTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWS-RGDKAIME 593
                 K+ + D    ++  L   ++V V+     R E  IS E    A W  +G+  +  
Sbjct: 5597 DKTSGKLDIEDREIKLVRPL---HSVEVMETETARFETEIS-EDDIHANWKLKGEALLQT 5652

Query: 594  GSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTV 653
                I+ E    S  LV+     D +G       N    AH  +K +V+    P    TV
Sbjct: 5653 PDCEIKEEGKIHS--LVLHNCRLDQTGGVDFQAANVKSSAHLRVKPRVIGLLRPLKDVTV 5710

Query: 654  T 654
            T
Sbjct: 5711 T 5711



 Score = 95.5 bits (236), Expect = 3e-19
 Identities = 111/492 (22%), Positives = 196/492 (39%), Gaps = 52/492 (10%)

Query: 673   GSPILGYFIERKKKQSSRWMRLNFDLCKET-TFEPKKMIEGVAYEVRIFAVNAIGISKPS 731
             G P+    + R        MR N ++  E  T   K+ +   A    I A N+ G +K  
Sbjct: 20005 GKPLPKVTLSRDGVPLKATMRFNTEITAENLTINLKESVTADAGRYEITAANSSGTTKAF 20064

Query: 732   MPSRPFVPLAVTSPPT-LLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWI 790
             +     V L    PPT  + +  +T+ +VT++W PP + G + +  Y+L      T  W 
Sbjct: 20065 IN---IVVLDRPGPPTGPVVISDITEESVTLKWEPPKYDGGSQVTNYILLKRETSTAVWT 20121

Query: 791   VANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVK---EIIEPPKIR 847
               +   + +T   +  L T  +   R+KA N  G S+    S  + VK       PP   
Sbjct: 20122 EVSAT-VARTMMKVMKLTTGEEYQFRIKAENRFGISD-HIDSACVTVKLPYTTPGPPSTP 20179

Query: 848   IPRHLKQTYI-----RRVGEAVNLVIPF--QGKPRPELTWKKDGAEIDKNQINIRNSETD 900
                ++ +  I       V    + V+ +  + K R  + W+K       N++ IR +   
Sbjct: 20180 WVTNVTRESITVGWHEPVSNGGSAVVGYHLEMKDRNSILWQK------ANKLVIRTTH-- 20231

Query: 901   TIIFIRKAERSHSGKYDLQVKVDKFVETA-----SIDIQIIDRPGPPQIVKIEDVWGENV 955
                  +    S    Y+ +V  +           S  +  ID   PP+ V+I D+   +V
Sbjct: 20232 ----FKVTTISAGLIYEFRVYAENAAGVGKPSHPSEPVLAIDACEPPRNVRITDISKNSV 20287

Query: 956   ALTWTPPKDDGNAAITGYTIQKADKKSMEWFTV-IEHYHRTSATITELVIGNEYYFRVFS 1014
             +L+W  P  DG + ITGY +++ D     W      +   T   I+ L   ++Y FRVF+
Sbjct: 20288 SLSWQQPAFDGGSKITGYIVERRDLPDGRWTKASFTNVTETQFIISGLTQNSQYEFRVFA 20347

Query: 1015  ENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAI---AGYNA 1071
              N  G     +++  S V+         P+    D    P+   PL  T  +   AG + 
Sbjct: 20348 RNAVG-----SISNPSEVVG--------PI-TCIDSYGGPVIDLPLEYTEVVKYRAGTSV 20393

Query: 1072  TLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVND 1131
              L   + G P P I W K+   +  +    + +   + ++ I+     + G Y  K  N 
Sbjct: 20394 KLRAGISGKPAPTIEWYKDDKELQTNALVCVENTTDLASILIKDADRLNSGCYELKLRNA 20453

Query: 1132  LGTVEIECKLEV 1143
             +G+     ++++
Sbjct: 20454 MGSASATIRVQI 20465



 Score = 94.4 bits (233), Expect = 6e-19
 Identities = 105/462 (22%), Positives = 179/462 (38%), Gaps = 52/462 (11%)

Query: 697   DLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTD 756
             D C+E        +   A E  I  +N I + KP  P+ P            + +D VT 
Sbjct: 15712 DACREDVGHYVVKLTNSAGEA-IETLNVIVLDKPGPPTGP------------VKMDEVTA 15758

Query: 757   TTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVR 816
              ++T+ W PP + G + ++ Y++E     T  W + +   + +T      L T  +   R
Sbjct: 15759 DSITLSWGPPKYDGGSSINNYIVEKRDTSTTTWQIVSAT-VARTTIKACRLKTGCEYQFR 15817

Query: 817   VKAVNAAGAS-----EPKYYSQPILVKEIIEPPKIRIPRH--LKQTYIRRVGEAVNLVIP 869
             + A N  G S     EP     P  V      P + +     ++  +   + +  + VI 
Sbjct: 15818 IAAENRYGKSTYLNSEPTVAQYPFKVPGPPGTPVVTLSSRDSMEVQWNEPISDGGSRVIG 15877

Query: 870   F--QGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVE 927
             +  + K R  + W K    ++K  I     +T  +    + E   S +  + +     V 
Sbjct: 15878 YHLERKERNSILWVK----LNKTPIPQTKFKTTGLEEGVEYEFRVSAENIVGIGKPSKVS 15933

Query: 928   TASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFT 987
                +     D PG P+ + +      +V L W  P  DG + ITGY ++K +     W  
Sbjct: 15934 ECYVARDPCDPPGRPEAIIVTR---NSVTLQWKKPTYDGGSKITGYIVEKKELPEGRWMK 15990

Query: 988   V-IEHYHRTSATITELVIGNEYYFRVFSENMCGL-SEDATMTKESAVIARDG----KIYK 1041
                 +   T   +T LV  + Y FRV + N  G+ SE +  T   A+ ARD     +I  
Sbjct: 15991 ASFTNIIDTHFEVTGLVEDHRYEFRVIARNAAGVFSEPSEST--GAITARDEVDPPRISM 16048

Query: 1042  NPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYR 1101
             +P Y+D                   AG +  ++  + G P P I W+K    + +  R  
Sbjct: 16049 DPKYKD--------------TIVVHAGESFKVDADIYGKPIPTIQWIKGDQELSNTARLE 16094

Query: 1102  MFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1143
             + S     +L ++     D G Y  KA N  G   +   ++V
Sbjct: 16095 IKSTDFATSLSVKDAVRVDSGNYILKAKNVAGERSVTVNVKV 16136



 Score = 94.4 bits (233), Expect = 6e-19
 Identities = 148/652 (22%), Positives = 260/652 (39%), Gaps = 111/652 (17%)

Query: 51    SRALERKDSDWTLVE---TPPGEEQAKQNANSQLSILFIEKPQGGTVKVGEDITFIAKVK 107
             S+  E K SD    E   T   E +A +  +S+  I  +   Q  TV       F  K  
Sbjct: 26322 SKISETKKSDQKTTESTVTRKTEPKAPEPISSKPVI--VTGLQDTTVSSDSVAKFAVKAT 26379

Query: 108   AEDLLRKPTIKWFK--------GKWMDLASKAGKHLQLKETFERHSRVYTFEMQIIKAKD 159
              E    +PT  W K        GK+     K G  L++ +T    S +YT  ++      
Sbjct: 26380 GEP---RPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVK------ 26430

Query: 160   NFAGNYR--CEVTYKDKFDSCSFDLEVHESTGTTPNIDIRSAFKRSGEGQEDAGELDFSG 217
             N AG+    C++T K   D+ +  +   +++  TP        K++   +E + +   S 
Sbjct: 26431 NSAGSVSSSCKLTIKAIKDTEAQKVSTQKTSEITPQ-------KKAVVQEEISQKALRSE 26483

Query: 218   LLKRREVKQQE------EEPQVDVWELLKNAKPSEYEKIAFQYGITDLRGMLKRLKRMRR 271
              +K  E K QE      E  +V + E +K +  +  EK      IT              
Sbjct: 26484 EIKMSEAKSQEKLALKEEASKVLISEEVKKSAATSLEKSIVHEEITKTS--------QAS 26535

Query: 272   EEKKSAAFAKILDPAYQVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQ 331
             EE ++ A  K       +++G R+     +A    +VKW  NG E+  S +Y +   G  
Sbjct: 26536 EEVRTHAEIKAFSTQMSINEGQRLVLKANIAGAT-DVKWVLNGVELTNSEEYRYGVSGSD 26594

Query: 332   RILFINNCQMTDDSEYYVTA----GDEKCSTELFVREPPIMVTKQLEDTTAYC------- 380
             + L I      D+      +    G  KC  +L        ++K+L D  A+        
Sbjct: 26595 QTLTIKQASHRDEGILTCISKTKEGIVKCQYDL-------TLSKELSDAPAFISQPRSQN 26647

Query: 381   ---GERVELECEVS-EDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAA 436
                G+ V   CE+S E    ++WFKN   I     S   I      + L I  A+ +D+ 
Sbjct: 26648 INEGQNVLFTCEISGEPSPEIEWFKNNLPI--SISSNVSISRSRNVYSLEIRNASVSDSG 26705

Query: 437   EYSVMTTG--GQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCEISENIPGKWTKNGL 494
             +Y++      GQ SA  S+      ++ PL ++     +E+ L+     ++ G ++   +
Sbjct: 26706 KYTIKAKNFRGQCSATASL------MVLPLVEEP---SREVVLRTSGDTSLQGSFSSQSV 26756

Query: 495   PVQESDR-----------LKVVHKGRIHKLVIANALTEDEGDYVFAPDAY----NVT--- 536
              +  S +              + + +   +   +  +  E     +  ++    N+T   
Sbjct: 26757 QMSASKQEASFSSFSSSSASSMTEMKFASMSAQSMSSMQESFVEMSSSSFMGISNMTQLE 26816

Query: 537   ------LPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKA 590
                   L A +  I PPKI  + L +D  +++  G  L +    +GEP P+  WS G + 
Sbjct: 26817 SSTSKMLKAGIRGI-PPKI--EALPSD--ISIDEGKVLTVACAFTGEPTPEVTWSCGGRK 26871

Query: 591   I-MEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKV 641
             I  +  GR   E+  D +TL+I   ++ D G+Y ++L NE G   A++ + +
Sbjct: 26872 IHSQEQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNIHI 26923



 Score = 93.2 bits (230), Expect = 1e-18
 Identities = 201/953 (21%), Positives = 329/953 (34%), Gaps = 190/953 (19%)

Query: 284   DPAYQVDKGGRVRFVVEL-ADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMT 342
             D  Y   +    R  + +   P   V W K    +   T+   E       L + +CQ +
Sbjct: 13492 DLCYLAKENSNFRLKIPIKGKPAPSVSWKKGEDPLATDTRVSVESSAVNTTLIVYDCQKS 13551

Query: 343   DDSEYYVT----AGDEKCSTELFVREPPIMVTKQL--EDTTAYC------------GERV 384
             D  +Y +T    AG ++ +  + V   P + T  +  ++ TA              G  +
Sbjct: 13552 DAGKYTITLKNVAGTKEGTISIKVVGKPGIPTGPIKFDEVTAEAMTLKWAPPKDDGGSEI 13611

Query: 385   ELECEVSEDDANVKWFKNGEEIIPGPKSRYRI-----------RVEGKKHILIIEGATKA 433
                     D  N KW      +    K+ +R+           RV  +    + EG    
Sbjct: 13612 TNYILEKRDSVNNKWVTCASAV---QKTTFRVTRLHEGMEYTFRVSAENKYGVGEGLKSE 13668

Query: 434   DAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEIC-LKCEISENIPGKWTK- 491
                                VD++   +    TD     G  I     E  E     W + 
Sbjct: 13669 PIVARHPFDVPDAPPPPNIVDVRHDSVSLTWTDPKKTGGSPITGYHLEFKERNSLLWKRA 13728

Query: 492   NGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKIIL 551
             N  P++  D  KV              LTE   +Y F   A N+    K  +   P + L
Sbjct: 13729 NKTPIRMRD-FKVT------------GLTEGL-EYEFRVMAINLAGVGKPSLPSEPVVAL 13774

Query: 552   DGLDAD----------NTVTVI-------AGNKLRLEIPISGEPPPKAMWSRGDKAIMEG 594
             D +D            N+VT+I        G+KL   I    + P K+ W + +      
Sbjct: 13775 DPIDPPGKPEVINITRNSVTLIWTEPKYDGGHKLTGYIVEKRDLPSKS-WMKANHV---- 13829

Query: 595   SGRIRTESYPDSSTLVIDIAERDDSGVYH--INLKNEAGEAHA-SIKVKVVDFPDPPVAP 651
                    + P+ +  V D+ E    G Y   I  KN AG   A S   + +   D   AP
Sbjct: 13830 -------NVPECAFTVTDLVE---GGKYEFRIRAKNTAGAISAPSESTETIICKDEYEAP 13879

Query: 652   TVTEVGDDWCIMNWEPPAYDG-----GSPIL--GYFIERKKKQSSRWMRLNFDL----CK 700
             T+            +P   DG     G  I+     I  K    S W +   D+      
Sbjct: 13880 TIV----------LDPTIKDGLTIKAGDTIVLNAISILGKPLPKSSWSKAGKDIRPSDIT 13929

Query: 701   ETTFEPKKMIEGVAYEVR-------IFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDS 753
             + T  P   +  + Y  R       I A N  G     +       L V  PP  + + +
Sbjct: 13930 QITSTPTSSMLTIKYATRKDAGEYTITATNPFGTKVEHVK---VTVLDVPGPPGPVEISN 13986

Query: 754   VTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKI 813
             V+    T+ W PP   G + +  Y+LE        W V ++D I   +   T L    + 
Sbjct: 13987 VSAEKATLTWTPPLEDGGSPIKSYILEKRETSRLLWTVVSED-IQSCRHVATKLIQGNEY 14045

Query: 814   FVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGK 873
               RV AVN  G  EP   S+P+ + +   PP                G      +    K
Sbjct: 14046 IFRVSAVNHYGKGEP-VQSEPVKMVDRFGPP----------------GPPEKPEVSNVTK 14088

Query: 874   PRPELTWKKD----GAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETA 929
                 ++WK+     G+EI    +  R  E  ++ ++R  +   S   DL+ KV    E +
Sbjct: 14089 NTATVSWKRPVDDGGSEITGYHVERR--EKKSLRWVRAIKTPVS---DLRCKVTGLQEGS 14143

Query: 930   SIDIQIIDR-----------------------PGPPQIVKIEDVWGENVALTWTPPKDDG 966
             + + ++                          PGPP    + D   ++ +L W  P  DG
Sbjct: 14144 TYEFRVSAENRAGIGPPSEASDSVLMKDAAYPPGPPSNPHVTDTTKKSASLAWGKPHYDG 14203

Query: 967   NAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGN-----EYYFRVFSENMCGLS 1021
                ITGY ++        W   I+    T+  IT+ V+ +     +Y FR+ + N  G+ 
Sbjct: 14204 GLEITGYVVEHQKVGDEAW---IKDTTGTALRITQFVVPDLQTKEKYNFRISAINDAGVG 14260

Query: 1022  EDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAI-AGYNATLNCSVRGN 1080
             E A +         D +I +  +  DF+          L  T  + AG +  +   ++G 
Sbjct: 14261 EPAVIP--------DVEIVEREMAPDFELDAE------LRRTLVVRAGLSIRIFVPIKGR 14306

Query: 1081  PKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLG 1133
             P P++TW K+ + + +  R  + + +    L I + + YD G +     N  G
Sbjct: 14307 PAPEVTWTKDNINLKN--RANIENTESFTLLIIPECNRYDTGKFVMTIENPAG 14357



 Score = 93.2 bits (230), Expect = 1e-18
 Identities = 127/584 (21%), Positives = 221/584 (37%), Gaps = 94/584 (16%)

Query: 606   SSTLVIDIAERDDSGV--YHINLKNEAGEAH----ASIKVKV------VDFPDPPVAPTV 653
             S T  I++++  +  V  + +  KNE G +       I VK       VD  D P A   
Sbjct: 21018 SKTCEIEVSQLKEQSVLEFRVFAKNEKGLSDPVTIGPITVKELIITPEVDLSDIPGAQVT 21077

Query: 654   TEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKET-TFEPKKMIEG 712
               +G +   ++ E P      P + +  +    + S ++R +    K T + +  K   G
Sbjct: 21078 VRIGHN---VHLELPYKGKPKPSISWLKDGLPLKESEFVRFSKTENKITLSIKNAKKEHG 21134

Query: 713   VAYEVRI--------FAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWR 764
               Y V +          +  I +  PS P  P            +  D +   +V + W 
Sbjct: 21135 GKYTVILDNAVCRIAVPITVITLGPPSKPKGP------------IRFDEIKADSVILSWD 21182

Query: 765   PPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAG 824
              P+  G   +  Y +E       +W +     + +T F +  L  DA+   RV+A N  G
Sbjct: 21183 VPEDNGGGEITCYSIEKRETSQTNWKMVCSS-VARTTFKVPNLVKDAEYQFRVRAENRYG 21241

Query: 825   ASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKD- 883
              S      QP++   I+   + RIP           G+ V   +   G     LTW    
Sbjct: 21242 VS------QPLVSSIIVAKHQFRIPGP--------PGKPVIYNVTSDGM---SLTWDAPV 21284

Query: 884   ---GAEIDKNQINIRNSETDTIIFIRKAERSHSGK------------YDLQVKVDKFVET 928
                G+E+     ++   E ++I++ +      SG+            Y  +V  +     
Sbjct: 21285 YDGGSEV--TGFHVEKKERNSILWQKVNTSPISGREYRATGLVEGLDYQFRVYAENSAGL 21342

Query: 929   AS--------IDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADK 980
             +S        + +  +D PG P  +   DV  E + L W PP  DG + I GY+I+K   
Sbjct: 21343 SSPSDPSKFTLAVSPVDPPGTPDYI---DVTRETITLKWNPPLRDGGSKIVGYSIEKRQG 21399

Query: 981   KSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIY 1040
                              T+T L  G+ Y FR+ + N  G     + +    ++ RD  + 
Sbjct: 21400 NERWVRCNFTDVSECQYTVTGLSPGDRYEFRIIARNAVGTISPPSQSS-GIIMTRDENV- 21457

Query: 1041  KNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRY 1100
               P   +F     P +   L+     +G +  +   V+G P P++TW K+ V I      
Sbjct: 21458 --PPIVEF----GPEYFDGLIIK---SGESLRIKALVQGRPVPRVTWFKDGVEIEKRMNM 21508

Query: 1101  RMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVK 1144
              +    G  +L +R  +    G Y  +A N  G+ + E K++V+
Sbjct: 21509 EITDVLGSTSLFVRDATRDHRGVYTVEAKNASGSAKAEIKVKVQ 21552



 Score = 92.8 bits (229), Expect = 2e-18
 Identities = 113/454 (24%), Positives = 172/454 (37%), Gaps = 74/454 (16%)

Query: 718   RIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGY 777
             R  AVN   + KP  P+ P            L ++ +T    ++ W  P   G A +D Y
Sbjct: 19374 RSVAVNCKVLDKPGPPAGP------------LEINGLTAEKCSLSWGRPQEDGGADIDYY 19421

Query: 778   VLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILV 837
             ++E        W +   +L   T   +T L    +   RV  VN  G  EP    + + +
Sbjct: 19422 IVEKRETSHLAWTICEGEL-QMTSCKVTKLLKGNEYIFRVTGVNKYGVGEPL---ESVAI 19477

Query: 838   KEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNS 897
             K +        P  L+ T + +  E++ L        RPE      G+EI    I  R  
Sbjct: 19478 KALDPFTVPSPPTSLEITSVTK--ESMTLCWS-----RPE---SDGGSEISGYIIERR-- 19525

Query: 898   ETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQI---------------------- 935
             E +++ ++R  ++     YDL+VK     E    + ++                      
Sbjct: 19526 EKNSLRWVRVNKKP---VYDLRVKSTGLREGCEYEYRVYAENAAGLSLPSETSPLIRAED 19582

Query: 936   -IDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHR 994
              +  P PP   KI D     + + W  P  DG A ITGYT++       +W T I+    
Sbjct: 19583 PVFLPSPPSKPKIVDSGKTTITIAWVKPLFDGGAPITGYTVEYKKSDDTDWKTSIQSLRG 19642

Query: 995   TSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAP 1054
             T  TI+ L  G EY FRV S N  G S+ +  +        D +I K    E     ++ 
Sbjct: 19643 TEYTISGLTTGAEYVFRVKSVNKVGASDPSDSS--------DPQIAKEREEEPLFDIDSE 19694

Query: 1055  MFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMF--SNQGVCTLE 1112
             M    +V     AG + T+    RG P P + W K       D R R +  +     +L 
Sbjct: 19695 MRKTLIVK----AGASFTMTVPFRGRPVPNVLWSKPDT----DLRTRAYVDTTDSRTSLT 19746

Query: 1113  IRKPSPYDGGTYCCKAVNDLGTVEIECKLEVKVI 1146
             I   +  D G Y     N L    +   L VKV+
Sbjct: 19747 IENANRNDSGKYTLTIQNVLSAASL--TLVVKVL 19778



 Score = 92.4 bits (228), Expect = 2e-18
 Identities = 133/609 (21%), Positives = 230/609 (37%), Gaps = 111/609 (18%)

Query: 584  WSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVD 643
            WSR +K+++    +   +   +  T V  +   + +G    +  ++   AH  I      
Sbjct: 8451 WSRVNKSLLNAL-KANVDGLLEGLTYVFRVCAENAAGPGKFSPPSDPKTAHDPISP---- 8505

Query: 644  FPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETT 703
             P PP+ P VT+       + WEPPA++GG  I+GYF++++   ++ W R    + K   
Sbjct: 8506 -PGPPI-PRVTDTSSTTIELEWEPPAFNGGGEIVGYFVDKQLVGTNEWSRCTEKMIKVRQ 8563

Query: 704  FEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRW 763
            +  K++ EG  Y++R+ AVNA G   P        P+ V  P                  
Sbjct: 8564 YTVKEIREGADYKLRVSAVNAAGEGPPGETQ----PVTVAEPQ----------------- 8602

Query: 764  RPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAA 823
             PP    A  LD  V      G +  I+A K L  +    +TG P   K++ +       
Sbjct: 8603 EPP----AVELDVSVKG----GIQ--IMAGKTL--RIPAVVTGRPVPTKVWTK------- 8643

Query: 824  GASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLV--------IPFQGKPR 875
               E +     +++  +    ++ I   L++ + R V  A N          +     P 
Sbjct: 8644 --EEGELDKDRVVIDNVGTKSELIIKDALRKDHGRYVITATNSCGSKFAAARVEVFDVPG 8701

Query: 876  PELTWKKDGAEIDKNQINIRNSETDT------IIFIRKAERSHSGKYDLQVKVDKFVETA 929
            P L  K          +N  + E D        I  RK  + H+ +  ++ +  K   T 
Sbjct: 8702 PVLDLKPVVTNRKMCLLNWSDPEDDGGSEITGFIIERKDAKMHTWRQPIETERSKCDITG 8761

Query: 930  SID------------------------IQIIDRPGPP---QIVKIEDVWGENVALTWTPP 962
             ++                        I  +D  GPP   + +   +     + L W  P
Sbjct: 8762 LLEGQEYKFRVIAKNKFGCGPPVEIGPILAVDPLGPPTSPERLTYTERTKSTITLDWKEP 8821

Query: 963  KDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYY-FRVFSENMCGLS 1021
            + +G + I GY I+K      ++  V +    T++ + E +  ++ Y FRV + N  G S
Sbjct: 8822 RSNGGSPIQGYIIEKRRHDKPDFERVNKRLCPTTSFLVENLDEHQMYEFRVKAVNEIGES 8881

Query: 1022 EDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAI-AGYNATLNCSVRGN 1080
            E +       V+ +D ++               +      +T  + AG    +   V G 
Sbjct: 8882 EPSLPLN---VVIQDDEVPPT----------IKLRLSVRGDTIKVKAGEPVHIPADVTGL 8928

Query: 1081 PKPKITWMKNKVAI------VDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGT 1134
            P PKI W KN+  I      +   +  +  ++    L I K    D GTY   A N LG+
Sbjct: 8929 PMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAVREDKGTYTVTASNRLGS 8988

Query: 1135 VEIECKLEV 1143
            V     +EV
Sbjct: 8989 VFRNVHVEV 8997



 Score = 92.0 bits (227), Expect = 3e-18
 Identities = 98/417 (23%), Positives = 169/417 (40%), Gaps = 47/417 (11%)

Query: 745   PPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTI 804
             PP  + +D V+  ++T+ W PP++ G   +  Y++E     +  W + ++  + +T   I
Sbjct: 18993 PPGPIRIDEVSCDSITISWNPPEYDGGCQISNYIVEKKETTSTTWHIVSQ-AVARTSIKI 19051

Query: 805   TGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPP----KIRIPRHLKQTYIRR- 859
               L T ++   RV A N  G S     S  ++ +    PP      ++    K T +   
Sbjct: 19052 VRLTTGSEYQFRVCAENRYGKSSYSE-SSAVVAEYPFSPPGPPGTPKVVHATKSTMLVTW 19110

Query: 860   ---VGEAVNLVIPF--QGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSG 914
                V +  + VI +  + K R  + W K       N+I I     DT + +   +     
Sbjct: 19111 QVPVNDGGSRVIGYHLEYKERSSILWSK------ANKILI----ADTQMKVSGLDEGLMY 19160

Query: 915   KYDLQVKVDKFVETASIDIQII------DRPGPPQIVKIEDVWGENVALTWTPPKDDGNA 968
             +Y +  +    +   S   + +      D PG P++  I     ++V+L W+ P  DG A
Sbjct: 19161 EYRVYAENIAGIGKCSKSCEPVPARDPCDPPGQPEVTNITR---KSVSLKWSKPHYDGGA 19217

Query: 969   AITGYTIQKADKKSMEWFTV-IEHYHRTSATITELVIGNEYYFRVFSENMC-GLSEDATM 1026
              ITGY +++ +     W      +   T   +TEL     Y FRVF+ N    +SE +  
Sbjct: 19218 KITGYIVERRELPDGRWLKCNYTNIQETYFEVTELTEDQRYEFRVFARNAADSVSEPSES 19277

Query: 1027  TKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKIT 1086
             T    +I +D  +    V  D  F +  +           AG    +N  + G P P I+
Sbjct: 19278 T--GPIIVKDD-VEPPRVMMDVKFRDVIVVK---------AGEVLKINADIAGRPLPVIS 19325

Query: 1087  WMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGT--VEIECKL 1141
             W K+ + I +  R  + S      L ++     D G Y     N  GT  V + CK+
Sbjct: 19326 WAKDGIEIEERARTEIISTDNHTLLTVKDCIRRDTGQYVLTLKNVAGTRSVAVNCKV 19382



 Score = 92.0 bits (227), Expect = 3e-18
 Identities = 69/216 (31%), Positives = 100/216 (46%), Gaps = 18/216 (8%)

Query: 937   DRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTV-IEHYHRT 995
             ++PG P    I  V  ++  + W PP  DG A I  Y ++K +KK  +W +V  E    T
Sbjct: 24326 EKPGAPGKPTITAVTKDSCVVAWKPPASDGGAKIRNYYLEKREKKQNKWISVTTEEIRET 24385

Query: 996   SATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFS-EAP 1054
               ++  L+ G EY FRV  EN+ G SE + +++              P+    D   +AP
Sbjct: 24386 VFSVKNLIEGLEYEFRVKCENLGGESEWSEISE--------------PITPKSDVPIQAP 24431

Query: 1055  MFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMK-NKVAIVDDPRYRMFS-NQGVCTLE 1112
              F + L N       NATL C V G+PKP + W +  K  I D  +YR+     G   L 
Sbjct: 24432 HFKEELRNLNVRYQSNATLVCKVTGHPKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQLI 24491

Query: 1113  IRKPSPYDGGTYCCKAVNDLGTVEIECKLEVKVIAQ 1148
             I   +  D   Y  +A N  G+V     LEV+V A+
Sbjct: 24492 IASVTDDDATVYQVRATNQGGSVSGTASLEVEVPAK 24527



 Score = 90.9 bits (224), Expect = 6e-18
 Identities = 99/442 (22%), Positives = 167/442 (37%), Gaps = 60/442 (13%)

Query: 722   VNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEY 781
             +  + +  P  P  PF             +  +     ++ W  P   G + +  Y++E 
Sbjct: 12487 IKVVVMDAPGPPQPPF------------DISDIDADACSLSWHIPLEDGGSNITNYIVEK 12534

Query: 782   CFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEI- 840
             C     DW+ A    + KT   +  L    +   RV+A N  G SEP   + P +V +  
Sbjct: 12535 CDVSRGDWVTALAS-VTKTSCRVGKLIPGQEYIFRVRAENRFGISEP--LTSPKMVAQFP 12591

Query: 841   ----IEPPKIRIPRHLKQ----TYIRRVGEAVNLVIPF--QGKPRPELTWKKDGAEIDKN 890
                  EP   R+ +  K      + R   +  + +I +  + K R  L W K       N
Sbjct: 12592 FGVPSEPKNARVTKVNKDCIFVAWDRPDSDGGSPIIGYLIERKERNSLLWVK------AN 12645

Query: 891   QINIRNSETDTIIFIRKAERS------HSGKYDLQVKVDKFVETASIDIQIIDRPGPPQI 944
                +R++E      +   E S      +        K  ++V TA + +   D PG P++
Sbjct: 12646 DTLVRSTEYPCAGLVEGLEYSFRIYALNKAGSSPPSKPTEYV-TARMPV---DPPGKPEV 12701

Query: 945   VKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWF---TVIEHYHRTSATITE 1001
             +   DV    V+L W  PK DG + I GY ++       +W    T      +   T T 
Sbjct: 12702 I---DVTKSTVSLIWARPKHDGGSKIIGYFVEACKLPGDKWVRCNTAPHQIPQEEYTATG 12758

Query: 1002  LVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLV 1061
             L    +Y FR  +     +S  +  +    ++A +      P   D   +   + T    
Sbjct: 12759 LEEKAQYQFRAIARTAVNISPPSEPSDPVTILAENV-----PPRIDLSVAMKSLLTVK-- 12811

Query: 1062  NTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDG 1121
                  AG N  L+ +V G P P ++W K+   +      +M   + +CTLE+   +  D 
Sbjct: 12812 -----AGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGIKMAMQRNLCTLELFSVNRKDS 12866

Query: 1122  GTYCCKAVNDLGTVEIECKLEV 1143
             G Y   A N  G+     KL+V
Sbjct: 12867 GDYTITAENSSGSKSATIKLKV 12888



 Score = 89.4 bits (220), Expect = 2e-17
 Identities = 117/543 (21%), Positives = 204/543 (37%), Gaps = 60/543 (11%)

Query: 628   NEAGEAHASIKVKVVDFPDP-----PVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIE 682
             N AG   AS+        DP     P  P VT+       + W PP  DGGS + GY +E
Sbjct: 9902  NAAGVGPASLPSDPATARDPIAPPGPPFPKVTDWTKSSADLEWSPPLKDGGSKVTGYIVE 9961

Query: 683   RKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAV 742
              K++    W +      + T      + EG  Y+   F V A+ I+    P    V   +
Sbjct: 9962  YKEEGKEEWEKGKDKEVRGTKLVVTGLKEGAFYK---FRVRAVNIAGIGEPGE--VTDVI 10016

Query: 743   TSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKF 802
                  L++ D   D +V  R R   H G        +      T  W +  + L  +   
Sbjct: 10017 EMKDRLVSPDLQLDASV--RDRIVVHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEATI 10074

Query: 803   TITGLPTDAKI---------FVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIP---- 849
               T + +   I            + A N AG  +     + I+V  +  P  +  P    
Sbjct: 10075 ETTAISSSMVIKNCQRSHQGVYSLLAKNEAGERK-----KTIIVDVLDVPGPVGTPFLAH 10129

Query: 850   ----RHLKQTYIRRVGEAVNLVIPF--QGKPRPELTWKKDGAEIDKNQINIRNSETDTII 903
                    K T+     +  + +  +  + +      W      + +    ++        
Sbjct: 10130 NLTNESCKLTWFSPEDDGGSPITNYVIEKRESDRRAWTPVTYTVTRQNATVQGLIQGKAY 10189

Query: 904   FIRKAERSHSGKYDLQVKVDKFVETASIDI--QIIDRPGPPQIVKIEDVWGENVALTWTP 961
             F R A  +  G       +  FVET+   +  + I  P  P+ +++++V    V LTW P
Sbjct: 10190 FFRIAAENSIG-------MGPFVETSEALVIREPITVPERPEDLEVKEVTKNTVTLTWNP 10242

Query: 962   PKDDGNAAITGYTIQKADKKSMEWFTVI-EHYHRTSATITELVIGNEYYFRVFSENMCGL 1020
             PK DG + I  Y ++     + ++  V  ++      T+  L  G+ Y +RV + N+ G 
Sbjct: 10243 PKYDGGSEIINYVLESRLIGTEKFHKVTNDNLLSRKYTVKGLKEGDTYEYRVSAVNIVGQ 10302

Query: 1021  SEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGN 1080
              + +  TK    I    ++    ++ DF        T  +   +A+ G  +       G 
Sbjct: 10303 GKPSFCTKP---ITCKDELAPPTLHLDF----RDKLTIRVGEAFALTGRYS-------GK 10348

Query: 1081  PKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECK 1140
             PKPK++W K++  +++D R  + +      LE  K    D G YC    N  G+ +  C+
Sbjct: 10349 PKPKVSWFKDEADVLEDDRTHIKTTPATLALEKIKAKRSDSGKYCVVVENSTGSRKGFCQ 10408

Query: 1141  LEV 1143
             + V
Sbjct: 10409 VNV 10411



 Score = 87.0 bits (214), Expect = 9e-17
 Identities = 96/437 (21%), Positives = 162/437 (37%), Gaps = 75/437 (17%)

Query: 625   NLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERK 684
             N+  ++  +  S  +  +D  DPP  P    +      + W  P Y GG  I  Y +E++
Sbjct: 14840 NMAGKSKPSKPSEPMLALDPIDPPGKPVPLNITRHTVTLKWAKPEYTGGFKITSYIVEKR 14899

Query: 685   KKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIG-ISKPSMPSRPFVPLAVT 743
                + RW++ NF    E  F    + E  AYE R+ A NA G IS PS PS         
Sbjct: 14900 DLPNGRWLKANFSNILENEFTVSGLTEDAAYEFRVIAKNAAGAISPPSEPSDAITCRDDV 14959

Query: 744   SPPTLLTVDSVTDTTV-------------------TMRWRP--PDHIGAAGLDGYVLEYC 782
               P +       DT +                   TM W     +  G A L+  + ++ 
Sbjct: 14960 EAPKIKVDVKFKDTVILKAGEAFRLEADVSGRPPPTMEWSKDGKELEGTAKLEIKIADFS 15019

Query: 783   FEGTEDWIVANKDLI--DKTKFTITGLPTD--AKIFVRVKAVNAAGASEPKYYSQPILVK 838
                     + NKD    D   +T+T       AK    VK ++  G  E      P+ V 
Sbjct: 15020 TN------LVNKDSTRRDSGAYTLTATNPGGFAKHIFNVKVLDRPGPPE-----GPLAVT 15068

Query: 839   EIIE--------PPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKN 890
             E+          PP            +   G  ++  I  Q +    L W    +E+   
Sbjct: 15069 EVTSEKCVLSWFPP------------LDDGGAKIDHYI-VQKRETSRLAWTNVASEVQVT 15115

Query: 891   QINI-RNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIED 949
             ++ + +  + +  IF   A   +     L+           + +     P PP+  ++  
Sbjct: 15116 KLKVTKLLKGNEYIFRVMAVNKYGVGEPLE-------SEPVLAVNPYGPPDPPKNPEVTT 15168

Query: 950   VWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWF-----TVIEHYHRTSATITELVI 1004
             +  +++ + W  P  DG + I  Y +++ DK    W      T+ +  ++ S     L  
Sbjct: 15169 ITKDSMVVCWGHPDSDGGSEIINYIVERRDKAGQRWIKCNKKTLTDLRYKVSG----LTE 15224

Query: 1005  GNEYYFRVFSENMCGLS 1021
             G+EY FR+ +EN  G+S
Sbjct: 15225 GHEYEFRIMAENAAGIS 15241



 Score = 86.3 bits (212), Expect = 2e-16
 Identities = 94/359 (26%), Positives = 158/359 (44%), Gaps = 23/359 (6%)

Query: 310  WYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVT---AGDEKCST-ELFVREP 365
            W K+G  IR S K+ F   G  R L I + Q++D  EY         EK ST +L V E 
Sbjct: 4654 WMKDGSNIRESPKHRFIADGKDRKLHIIDVQLSDAGEYTCVLRLGNKEKTSTAKLVVEEL 4713

Query: 366  PIMVTKQL-EDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHI 424
            P+   K L E+ T   G+ + L CE+++ + +V W K+G+ ++  P  R    V G    
Sbjct: 4714 PVRFVKTLEEEVTVVKGQPLYLSCELNK-ERDVVWRKDGKIVVEKP-GRIVPGVIGLMRA 4771

Query: 425  LIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKIL-----TPLTDQTVNLGKEICLKC 479
            L I  A   DA  Y+V T    ++ + S  +K ++++      P+ DQ V         C
Sbjct: 4772 LTINDADDTDAGTYTV-TVENANNLECSSCVKVVEVIRDWLVKPIRDQHVKPKGTAIFAC 4830

Query: 480  EISENIPG-KWTK--NGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVT 536
            +I+++ P  KW K  + +P + +D+ +++  G    L I NA+ ED  +Y  A +     
Sbjct: 4831 DIAKDTPNIKWFKGYDEIPAEPNDKTEILRDGNHLYLKIKNAMPEDIAEY--AVEIEGKR 4888

Query: 537  LPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSG 596
             PAK+ + +    +L  ++    VT+        +  IS    P     +G+  ++  S 
Sbjct: 4889 YPAKLTLGEREVELLKPIE---DVTIYEKESASFDAEISEADIPGQWKLKGE--LLRPSP 4943

Query: 597  RIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTE 655
                ++      L +   + D +G       N    A  ++K   +DF  P    TV E
Sbjct: 4944 TCEIKAEGGKRFLTLHKVKLDQAGEVLYQALNAITTAILTVKEIELDFAVPLKDVTVPE 5002



 Score = 86.3 bits (212), Expect = 2e-16
 Identities = 104/434 (23%), Positives = 164/434 (37%), Gaps = 44/434 (10%)

Query: 722   VNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEY 781
             ++ I + KP  P  P            +  D V+   V + W PP + G   +  Y++E 
Sbjct: 17900 LSVIVLEKPGPPVGP------------VRFDEVSADFVVISWEPPAYTGGCQISNYIVEK 17947

Query: 782   CFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILV---- 837
                 T  W + +   + +T   IT L T  +   R+ A N  G S P   S+ ++V    
Sbjct: 17948 RDTTTTTWHMVSAT-VARTTIKITKLKTGTEYQFRIFAENRYGKSAP-LDSKAVIVQYPF 18005

Query: 838   KEIIEPPKIRIPRHLKQTYIRRVGEAVN------LVIPFQGKPRPELTWKKDGAEIDKNQ 891
             KE   P    +    K   + +  E VN      +    + K +  + W K    ++K  
Sbjct: 18006 KEPGPPGTPFVTSISKDQMLVQWHEPVNDGGTKIIGYHLEQKEKNSILWVK----LNKTP 18061

Query: 892   INIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVW 951
             I     +T  +    + E   S +  + +     V    +     D PG P+ + I    
Sbjct: 18062 IQDTKFKTTGLDEGLEYEFKVSAENIVGIGKPSKVSECFVARDPCDPPGRPEAIVITR-- 18119

Query: 952   GENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTV-IEHYHRTSATITELVIGNEYYF 1010
               NV L W  P  DG + ITGY ++K D     W      +   T  T++ LV    Y F
Sbjct: 18120 -NNVTLKWKKPAYDGGSKITGYIVEKKDLPDGRWMKASFTNVLETEFTVSGLVEDQRYEF 18178

Query: 1011  RVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYN 1070
             RV + N  G   + +     A+ ARD     N   +       P +   +V     AG  
Sbjct: 18179 RVIARNAAGNFSEPS-DSSGAITARDEIDAPNASLD-------PKYKDVIV---VHAGET 18227

Query: 1071  ATLNCSVRGNPKPKITWMKNKVAIVDD-PRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAV 1129
               L   +RG P P + W K+   + +   R  + S     TL ++     DGG Y  K  
Sbjct: 18228 FVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRTDGGQYILKLS 18287

Query: 1130  NDLGTVEIECKLEV 1143
             N  GT  I   ++V
Sbjct: 18288 NVGGTKSIPITVKV 18301



 Score = 86.3 bits (212), Expect = 2e-16
 Identities = 78/292 (26%), Positives = 125/292 (42%), Gaps = 60/292 (20%)

Query: 290   DKGGRVRFV--VELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEY 347
             ++GG V++V  +E  D   +V WY   +++  S KY   ++    IL++ +    DD  Y
Sbjct: 25083 EEGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTY 25142

Query: 348   YVTA----GDEKCSTELFVR---------------------------EPPIMVTKQLEDT 376
                     G++    ELFV+                           E P   T  L + 
Sbjct: 25143 RCKVVNDYGEDSSYAELFVKGVREVYDYYCRRTMKKIKRRTDTMRLLERPPEFTLPLYNK 25202

Query: 377   TAYCGERVELECEVS-EDDANVKWFKNGEEIIPGPK-SRYRIRVEGKKHILIIEGATKAD 434
             TAY GE V     ++   + +V W+K+G++I PG    +Y    +   + L I   T  D
Sbjct: 25203 TAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDD 25262

Query: 435   AAEYSVMTTG--GQSS--AKLSVDLKPLKILTPLTDQTV-------------NLGKEICL 477
              AEY+V+     G+ S  AKL+V L P     P TD T+               G+ +C 
Sbjct: 25263 DAEYTVVARNKYGEDSCKAKLTVTLHP-----PPTDSTLRPMFKRLLANAECQEGQSVCF 25317

Query: 478   KCEISENIPG--KWTKNGLPVQESDRLKVVHKG-RIHKLVIANALTEDEGDY 526
             +  +S   P   KW K+G P+     ++++H+G   + L I + L ED G Y
Sbjct: 25318 EIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYY 25369



 Score = 85.9 bits (211), Expect = 2e-16
 Identities = 102/444 (22%), Positives = 169/444 (38%), Gaps = 63/444 (14%)

Query: 721   AVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLE 780
             ++  + + KP  P  P            +  D V+  ++T+ W PP + G   +  Y+++
Sbjct: 16817 SIEIVTLDKPDPPKGP------------VKFDDVSAESITLSWNPPLYTGGCQITNYIVQ 16864

Query: 781   YCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEI 840
                  T  W V +   + +T   +T L T  +   R+ A N  G S     S PI+ +  
Sbjct: 16865 KRDTTTTVWDVVSAT-VARTTLKVTKLKTGTEYQFRIFAENRYGQSFA-LESDPIVAQYP 16922

Query: 841   IE---PPKIRIPRHL-KQTYIRRVGEAVN------LVIPFQGKPRPELTWKKDGAEIDKN 890
              +   PP       + K + + +  E VN      +    + K R  + W K    ++K 
Sbjct: 16923 YKEPGPPGTPFATAISKDSMVIQWHEPVNNGGSPVIGYHLERKERNSILWTK----VNKT 16978

Query: 891   QINIRNSETDTIIFIRKAERSHSG-KYDLQVKVDKFVETAS--------IDIQIIDRPGP 941
              I+      DT     KA+    G +Y+ +V  +  V            +     D PG 
Sbjct: 16979 IIH------DTQF---KAQNLEEGIEYEFRVYAENIVGVGKASKNSECYVARDPCDPPGT 17029

Query: 942   PQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTV-IEHYHRTSATIT 1000
             P+ + ++      + L WT P  DG + ITGY ++K D     W      +   T  T++
Sbjct: 17030 PEPIMVKR---NEITLQWTKPVYDGGSMITGYIVEKRDLPDGRWMKASFTNVIETQFTVS 17086

Query: 1001  ELVIGNEYYFRVFSENMCG-LSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQP 1059
              L     Y FRV ++N  G +S+ +  T         G I      E    S  P F   
Sbjct: 17087 GLTEDQRYEFRVIAKNAAGAISKPSDST---------GPITAKDEVELPRISMDPKFRDT 17137

Query: 1060  LVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPY 1119
             +V     AG    L   V G P P I W++    I +  R  + +      L ++     
Sbjct: 17138 IVVN---AGETFRLEADVHGKPLPTIEWLRGDKEIEESARCEIKNTDFKALLIVKDAIRI 17194

Query: 1120  DGGTYCCKAVNDLGTVEIECKLEV 1143
             DGG Y  +A N  G+      ++V
Sbjct: 17195 DGGQYILRASNVAGSKSFPVNVKV 17218



 Score = 84.3 bits (207), Expect = 6e-16
 Identities = 105/451 (23%), Positives = 168/451 (37%), Gaps = 79/451 (17%)

Query: 722   VNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEY 781
             +  I + KP  P+ P            + +D +  T++T+ W PP+  G A L GYV+E 
Sbjct: 23327 IKVIILDKPGPPTGP------------IKIDEIDATSITISWEPPELDGGAPLSGYVVEQ 23374

Query: 782   CFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEII 841
                    W+  ++  + ++ F  T L    +   RV A N  G           L  E+I
Sbjct: 23375 RDAHRPGWLPVSES-VTRSTFKFTRLTEGNEYVFRVAATNRFGIGS-------YLQSEVI 23426

Query: 842   E-PPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTW---KKDGAE------IDKNQ 891
             E    IRIP           G    L I    +    LTW   + DG        +++ +
Sbjct: 23427 ECRSSIRIP-----------GPPETLQIFDVSRDGMTLTWYPPEDDGGSQVTGYIVERKE 23475

Query: 892   INIR-----NSETDTIIFIRKAERSHSGKYDLQVKVDKFVETAS--------IDIQIIDR 938
             +        N    T+   R    +   +Y+ +V       +          + +  I  
Sbjct: 23476 VRADRWVRVNKVPVTMTRYRSTGLTEGLEYEHRVTAINARGSGKPSRPSKPIVAMDPIAP 23535

Query: 939   PGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWF------TVIEHY 992
             PG PQ  ++ D    +V+L W+ P+D+G + +TGY I+       EW       T I  Y
Sbjct: 23536 PGKPQNPRVTDTTRTSVSLAWSVPEDEGGSKVTGYLIEMQKVDQHEWTKCNTTPTKIREY 23595

Query: 993   HRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSE 1052
                  T+T L  G EY FRV + N  G  E A        +    K+ +   Y D++  E
Sbjct: 23596 -----TLTHLPQGAEYRFRVLACNAGGPGEPAE-------VPGTVKVTEMLEYPDYELDE 23643

Query: 1053  APMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLE 1112
                  +     +   G    L   ++G P P   W K    I    R  + +++    L 
Sbjct: 23644 -----RYQEGIFVRQGGVIRLTIPIKGKPFPICKWTKEGQDI--SKRAMIATSETHTELV 23696

Query: 1113  IRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1143
             I++    D GTY     N  G   +  K+ V
Sbjct: 23697 IKEADRGDSGTYDLVLENKCGKKAVYIKVRV 23727



 Score = 82.8 bits (203), Expect = 2e-15
 Identities = 59/194 (30%), Positives = 92/194 (47%), Gaps = 21/194 (10%)

Query: 572  IPISGEPPPKAMWSRGDKAIMEGSGRIRTE-------SYPDSSTLVIDIAERDDSGVYHI 624
            + +  EPP         + ++E   R+ T        + PD +  V D+ E  +   + +
Sbjct: 7703 VDLKWEPPKNDGGRPIQRYVIEKKERLGTRWVKAGKTAGPDCNFRVTDVIEGTEVQ-FQV 7761

Query: 625  NLKNEAGEAHASIKVKVVDFPDPPVAPT------VTEVGDDWCIMNWEPPAYDGGSPILG 678
              +NEAG  H S   +++   DP   P+      VT+ G     + W+PP  +GGSPI+G
Sbjct: 7762 RAENEAGVGHPSEPTEILSIEDPTSPPSPPLDLHVTDAGRKHIAIAWKPPEKNGGSPIIG 7821

Query: 679  YFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVA----YEVRIFAVNAIGISKPSMPS 734
            Y +E     + +WMR+N    K+  F   K+ EGV     Y +R+ AVNAIG+S+PS  S
Sbjct: 7822 YHVEMCPVGTEKWMRVNSRPIKDLKF---KVEEGVVPDKEYVLRVRAVNAIGVSEPSEIS 7878

Query: 735  RPFVPLAVTSPPTL 748
               V       PT+
Sbjct: 7879 ENVVAKDPDCKPTI 7892



 Score = 77.8 bits (190), Expect = 6e-14
 Identities = 66/264 (25%), Positives = 116/264 (43%), Gaps = 27/264 (10%)

Query: 288  QVDKGGRVRFVVELADPKLEVKWYKNGQEI----RPSTKYIFEHKGCQRILFINNCQMTD 343
            QV +  R     E+ +  ++  WYK+G EI    +   KY+ E +     +FI+  + +D
Sbjct: 3111 QVIEKQRAVVEFEVNEDDVDAHWYKDGIEINFQVQERHKYVVERR--IHRMFISETRQSD 3168

Query: 344  DSEYYVTAGDEKCSTELFVREP-PIMVTKQLEDTTAYCGERVELECEVS-EDDANVKWFK 401
              EY   AG  + S  L+V  P P  V ++L+  T   G+       +S      + W+K
Sbjct: 3169 AGEYTFVAGRNRSSVTLYVNAPEPPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYK 3228

Query: 402  NGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAA--------EYSVMTTGGQSSAKL-- 451
              + +  G K ++    +G+++ L++  A   DAA        +Y V TT    S ++  
Sbjct: 3229 EEQLLSTGFKCKF--LHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPE 3286

Query: 452  ------SVDLKPLKILTPLTDQTVNLGKEICLKCEIS-ENIPGKWTKNGLPVQESDRLKV 504
                   + + P  I+TPL D   + G+    +C +S  ++   W      ++ S   ++
Sbjct: 3287 VVSPDQEMPVYPPAIITPLQDTVTSEGQPARFQCRVSGTDLKVSWYSKDKKIKPSRFFRM 3346

Query: 505  VHKGRIHKLVIANALTEDEGDYVF 528
                  ++L IA A  EDEG Y F
Sbjct: 3347 TQFEDTYQLEIAEAYPEDEGTYTF 3370



 Score = 75.5 bits (184), Expect = 3e-13
 Identities = 105/447 (23%), Positives = 173/447 (38%), Gaps = 58/447 (12%)

Query: 721   AVNAIGISKPSMPSR-PFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVL 779
             A NA G +K  +  +    P  V  P   +   ++T   +T+ W  P + G A +  Y++
Sbjct: 21536 AKNASGSAKAEIKVKVQDTPGKVVGP---IRFTNITGEKMTLWWDAPLNDGCAPITHYII 21592

Query: 780   EYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVK- 838
             E        W +  +D  +   +T   L    +   RV AVN  G   P   S P++ + 
Sbjct: 21593 EKRETSRLAWALI-EDKCEAQSYTAIKLINGNEYQFRVSAVNKFGVGRP-LDSDPVVAQI 21650

Query: 839   --EIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRN 896
                + + P I  P ++        G ++ L        RPE      G+EI +  +  R 
Sbjct: 21651 QYTVPDAPGIPEPSNI-------TGNSITLTWA-----RPE---SDGGSEIQQYILERRE 21695

Query: 897   SE-TDTIIFIRKAERSHS----------GKYDLQVKVDKF--VETASIDIQII------D 937
              + T  +  I K   S +           +Y+  V  +    V  AS   ++I      +
Sbjct: 21696 KKSTRWVKVISKRPISETRFKVTGLTEGNEYEFHVMAENAAGVGPASGISRLIKCREPVN 21755

Query: 938   RPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTV-IEHYHRTS 996
              PGPP +VK+ D     V+L W+ P  DG   I GY I+       +W  V  E   +T 
Sbjct: 21756 PPGPPTVVKVTDTSKTTVSLEWSKPVFDGGMEIIGYIIEMCKADLGDWHKVNAEACVKTR 21815

Query: 997   ATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMF 1056
              T+T+L  G EY FRV + N  G  +   +T     I    ++    +  D +F +  + 
Sbjct: 21816 YTVTDLQAGEEYKFRVSAINGAGKGDSCEVT---GTIKAVDRLTAPELDIDANFKQTHVV 21872

Query: 1057  TQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKP 1116
                       AG +  L  + +G P P   W K    +    R  + +     TL +   
Sbjct: 21873 R---------AGASIRLFIAYQGRPTPTAVWSKPDSNL--SLRADIHTTDSFSTLTVENC 21921

Query: 1117  SPYDGGTYCCKAVNDLGTVEIECKLEV 1143
             +  D G Y     N+ G+  I   ++V
Sbjct: 21922 NRNDAGKYTLTVENNSGSKSITFTVKV 21948



 Score = 73.9 bits (180), Expect = 8e-13
 Identities = 64/235 (27%), Positives = 91/235 (38%), Gaps = 46/235 (19%)

Query: 939  PGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRT-SA 997
            P PP  V++ +   E + +TW PP  DG + I GY I+K  K    W    EH     + 
Sbjct: 8083 PDPPVDVEVHNPTAEAMTITWKPPLYDGGSKIMGYIIEKIAKGEERWKRCNEHLVPILTY 8142

Query: 998  TITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFT 1057
            T   L  G EY FRV +EN  G+SE +  T  +  +            +  D  +  + T
Sbjct: 8143 TAKGLEEGKEYQFRVRAENAAGISEPSRATPPTKAV------------DPIDAPKVILRT 8190

Query: 1058 QPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDD-------PRYRM-------- 1102
               V      G    L+ S+ G+P P ITW+K++  IV +       P  R         
Sbjct: 8191 SLEVKR----GDEIALDASISGSPYPTITWIKDENVIVPEEIKKRAAPLVRRRKGEVQEE 8246

Query: 1103 --------------FSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1143
                           S +G   L +R     D G Y  K  ND G  +  C + V
Sbjct: 8247 EPFVLPLTQRLSIDNSKKGESQLRVRDSLRPDHGLYMIKVENDHGIAKAPCTVSV 8301



 Score = 73.9 bits (180), Expect = 8e-13
 Identities = 59/203 (29%), Positives = 83/203 (40%), Gaps = 14/203 (6%)

Query: 933   IQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHY 992
             ++  + P PP  + I D+    V+L W  PK DG + ITGY I+   K S +W T I   
Sbjct: 14462 VKASEAPSPPDSLNIMDITKSTVSLAWPKPKHDGGSKITGYVIEAQRKGSDQW-THITTV 14520

Query: 993   HRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSE 1052
                   +  L  G EY F+V + N  G S      +ES  +     + +  +  + D   
Sbjct: 14521 KGLECVVRNLTEGEEYTFQVMAVNSAGRSAP----RESRPVI----VKEQTMLPELDLRG 14572

Query: 1053  APMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLE 1112
                  Q LV   A AG N  +   V G PKP +TW K    +    R    +      L 
Sbjct: 14573 ---IYQKLV--IAKAGDNIKVEIPVLGRPKPTVTWKKGDQILKQTQRVNFETTATSTILN 14627

Query: 1113  IRKPSPYDGGTYCCKAVNDLGTV 1135
             I +    D G Y   A N +G V
Sbjct: 14628 INECVRSDSGPYPLTARNIVGEV 14650



 Score = 73.2 bits (178), Expect = 1e-12
 Identities = 52/197 (26%), Positives = 86/197 (43%), Gaps = 13/197 (6%)

Query: 937   DRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTS 996
             ++P PP+ + + D    +  L W  P  DG + ITGY ++   K S  W     H  + +
Sbjct: 22047 EQPAPPRRLDVVDTSKSSAVLAWLKPDHDGGSRITGYLLEMRQKGSDFWVEA-GHTKQLT 22105

Query: 997   ATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMF 1056
              T+  LV   EY FRV ++N  G SE       S+VI ++ +I           ++    
Sbjct: 22106 FTVERLVEKTEYEFRVKAKNDAGYSEPREAF--SSVIIKEPQIEPT--------ADLTGI 22155

Query: 1057  TQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKP 1116
             T  L+   A  G   T++  + G P PK+TW   ++ + +  R  + + +   TL ++  
Sbjct: 22156 TNQLITCKA--GSPFTIDVPISGRPAPKVTWKLEEMRLKETDRVSITTTKDRTTLTVKDS 22213

Query: 1117  SPYDGGTYCCKAVNDLG 1133
                D G Y     N  G
Sbjct: 22214 MRGDSGRYFLTLENTAG 22230



 Score = 68.9 bits (167), Expect = 3e-11
 Identities = 135/688 (19%), Positives = 232/688 (33%), Gaps = 145/688 (21%)

Query: 2     PEPTKKEENEVPAP----APPPEEPSKEKEAGTTPAKDEEEVSPPSALPPGLGSRALERK 57
             PEP  K    V +P    +P P  P       T P   E+    P + PP +        
Sbjct: 26172 PEPRVKSPEAVKSPKRVKSPEPSHPKAVSPTETKPTPTEKVQHLPVSAPPKITQ------ 26225

Query: 58    DSDWTLVETPPGEEQAKQNANSQLSILFIEKPQGGTVKVGEDITFIAKVKAEDLLRKPTI 117
                                        F++       +  ++I  +  V    +LR   +
Sbjct: 26226 ---------------------------FLK------AEASKEIAKLTCVVESSVLRAKEV 26252

Query: 118   KWFKGKWMDLASKAGKHLQLKETFERH-SRVYTFEMQIIKAKDNFAGNYRCEVTYKDKFD 176
              W+K          GK L+    F+ H S   T+E++I    ++  G Y CE+       
Sbjct: 26253 TWYKD---------GKKLKENGHFQFHYSADGTYELKINNLTESDQGEYVCEI------- 26296

Query: 177   SCSFDLEVHESTGTTPNIDIRSAFKRSGEGQEDAGELDFSG---------LLKRREVKQQ 227
                                       SGEG      L F G         + K  E K+ 
Sbjct: 26297 --------------------------SGEGGTSKTNLQFMGQAFKSIHEKVSKISETKKS 26330

Query: 228   EEEPQVDVWELLKNAKPSEYEKIAFQYGITDLRGMLKRLKRMRREEKKSAAFAKILDPAY 287
             +++       + +  +P   E I+                       K      + D   
Sbjct: 26331 DQKTTEST--VTRKTEPKAPEPIS----------------------SKPVIVTGLQDTTV 26366

Query: 288   QVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEY 347
               D   +   V    +P+    W K+G+ I    KY          L I+    +D   Y
Sbjct: 26367 SSDSVAKFA-VKATGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLY 26425

Query: 348   YVT----AGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNG 403
               T    AG    S +L ++   I  T+  + +T    E    +  V +++ + K  ++ 
Sbjct: 26426 TCTVKNSAGSVSSSCKLTIKA--IKDTEAQKVSTQKTSEITPQKKAVVQEEISQKALRSE 26483

Query: 404   EEIIPGPKSRYRIRVEGKKHILIIEGATKADAA---EYSVMTTGGQSSAKLSVDLKP-LK 459
             E  +   KS+ ++ ++ +   ++I    K  AA   E S++      +++ S +++   +
Sbjct: 26484 EIKMSEAKSQEKLALKEEASKVLISEEVKKSAATSLEKSIVHEEITKTSQASEEVRTHAE 26543

Query: 460   ILTPLTDQTVNLGKEICLKCEISENIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANAL 519
             I    T  ++N G+ + LK  I+     KW  NG+ +  S+  +    G    L I  A 
Sbjct: 26544 IKAFSTQMSINEGQRLVLKANIAGATDVKWVLNGVELTNSEEYRYGVSGSDQTLTIKQAS 26603

Query: 520   TEDEGDYV--------FAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLE 571
               DEG                Y++TL  ++   D P  I        +  +  G  +   
Sbjct: 26604 HRDEGILTCISKTKEGIVKCQYDLTLSKELS--DAPAFI----SQPRSQNINEGQNVLFT 26657

Query: 572   IPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAG 631
               ISGEP P+  W + +  I   S  +      +  +L I  A   DSG Y I  KN  G
Sbjct: 26658 CEISGEPSPEIEWFKNNLPI-SISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRG 26716

Query: 632   EAHASIKVKVVDFPDPPVAPTVTEVGDD 659
             +  A+  + V+   + P    V     D
Sbjct: 26717 QCSATASLMVLPLVEEPSREVVLRTSGD 26744



 Score = 66.2 bits (160), Expect = 2e-10
 Identities = 94/408 (23%), Positives = 146/408 (35%), Gaps = 40/408 (9%)

Query: 742   VTSPPT-LLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKT 800
             +  PPT  +  D V+   VT  W PP++ G   +  YV+E     +  W+     +I +T
Sbjct: 14661 IPGPPTGPIKFDEVSSDFVTFSWDPPENDGGVPISNYVVEMRQTDSTTWVELATTVI-RT 14719

Query: 801   KFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQ-TYIRR 859
              +  T L T  +   RVKA N  G   P   S  I+      P K+  P    Q T + +
Sbjct: 14720 TYKATRLTTGLEYQFRVKAQNRYGVG-PGITSACIVANY---PFKVPGPPGTPQVTAVTK 14775

Query: 860   VGEAVNLVIPF------------QGKPRPELTWKKDGAEIDKNQINIRNSETDTIIF-IR 906
                 ++   P             + K R  + W+     +    I   +  TD I +  R
Sbjct: 14776 DSMTISWHEPLSDGGSPILGYHVERKERNGILWQTVSKALVPGNIFKSSGLTDGIAYEFR 14835

Query: 907   KAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDG 966
                 + +GK     K  K  E   + +  ID PG P  + I       V L W  P+  G
Sbjct: 14836 VIAENMAGKS----KPSKPSEPM-LALDPIDPPGKPVPLNITR---HTVTLKWAKPEYTG 14887

Query: 967   NAAITGYTIQKADKKSMEWFTV-IEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDAT 1025
                IT Y ++K D  +  W      +      T++ L     Y FRV ++N  G     +
Sbjct: 14888 GFKITSYIVEKRDLPNGRWLKANFSNILENEFTVSGLTEDAAYEFRVIAKNAAGAISPPS 14947

Query: 1026  MTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKI 1085
                ++     D +  K  V  D  F +  +           AG    L   V G P P +
Sbjct: 14948 EPSDAITCRDDVEAPKIKV--DVKFKDTVILK---------AGEAFRLEADVSGRPPPTM 14996

Query: 1086  TWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLG 1133
              W K+   +    +  +        L  +  +  D G Y   A N  G
Sbjct: 14997 EWSKDGKELEGTAKLEIKIADFSTNLVNKDSTRRDSGAYTLTATNPGG 15044



 Score = 64.7 bits (156), Expect = 5e-10
 Identities = 75/303 (24%), Positives = 129/303 (42%), Gaps = 19/303 (6%)

Query: 366  PIMVTKQLEDT----TAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGK 421
            P+   K+++D     + + G     EC VS   A   W K+G  I   PK  +R   +GK
Sbjct: 4617 PLKFVKEIKDIILTESEFVGSSAIFECLVSPSTAITTWMKDGSNIRESPK--HRFIADGK 4674

Query: 422  KHILIIEGATKADAAEYSVMTTGGQ----SSAKLSVDLKPLKILTPLTDQ-TVNLGKEIC 476
               L I     +DA EY+ +   G     S+AKL V+  P++ +  L ++ TV  G+ + 
Sbjct: 4675 DRKLHIIDVQLSDAGEYTCVLRLGNKEKTSTAKLVVEELPVRFVKTLEEEVTVVKGQPLY 4734

Query: 477  LKCEISENIPGKWTKNG-LPVQESDRLKVVHKGRIHKLVIANALTEDEGDY-VFAPDAYN 534
            L CE+++     W K+G + V++  R+     G +  L I +A   D G Y V   +A N
Sbjct: 4735 LSCELNKERDVVWRKDGKIVVEKPGRIVPGVIGLMRALTINDADDTDAGTYTVTVENANN 4794

Query: 535  VTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEG 594
            +   + V V++   +I D L        +      +      +  P   W +G   I   
Sbjct: 4795 LECSSCVKVVE---VIRDWLVKPIRDQHVKPKGTAIFACDIAKDTPNIKWFKGYDEI-PA 4850

Query: 595  SGRIRTESYPDSSTLVIDI--AERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPT 652
                +TE   D + L + I  A  +D   Y + ++ +   A  ++  + V+   P    T
Sbjct: 4851 EPNDKTEILRDGNHLYLKIKNAMPEDIAEYAVEIEGKRYPAKLTLGEREVELLKPIEDVT 4910

Query: 653  VTE 655
            + E
Sbjct: 4911 IYE 4913



 Score = 63.5 bits (153), Expect = 1e-09
 Identities = 31/92 (33%), Positives = 43/92 (46%)

Query: 1054 PMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEI 1113
            P     L N   I G + TL C + G P P +TW +    I     +++    G+  L I
Sbjct: 897  PTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLMI 956

Query: 1114 RKPSPYDGGTYCCKAVNDLGTVEIECKLEVKV 1145
            R+    D G + C AVN+ GTV   C L V+V
Sbjct: 957  REAFAEDSGRFTCSAVNEAGTVSTSCYLAVQV 988



 Score = 61.2 bits (147), Expect = 5e-09
 Identities = 33/100 (33%), Positives = 54/100 (54%), Gaps = 6/100 (6%)

Query: 938   RPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEH-YHRTS 996
             RP PP++ K+     E + + W PP+ DG  +ITGY ++K +K S  W  V +       
Sbjct: 11901 RPDPPEVTKVSK---EEMTVVWNPPEYDGGKSITGYFLEKKEKHSTRWVPVNKSAIPERR 11957

Query: 997   ATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARD 1036
               +  L+  +EY FRV +EN  G+ E +  ++   V+A+D
Sbjct: 11958 MKVQNLLPDHEYQFRVKAENEIGIGEPSLPSR--PVVAKD 11995



 Score = 59.7 bits (143), Expect = 2e-08
 Identities = 74/324 (22%), Positives = 129/324 (39%), Gaps = 19/324 (5%)

Query: 836  LVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQ--GKPRPELTWKKDGAEID----- 888
            L +E   P +   P  + +  ++++ E  ++V   Q  G P+P + WKK G  +      
Sbjct: 1023 LTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRY 1082

Query: 889  KNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIE 948
            K   N +  E   +I +  A+   +G+Y + V+ +K  ET S    +++      ++K +
Sbjct: 1083 KVSYNKQTGECKLVISMTFAD--DAGEYTIVVR-NKHGET-SASASLLEEADYELLMKSQ 1138

Query: 949  DVWGENVALTWTPPKDDGNAAITGYTIQKADKK-SMEWFTVIEHYHRTSATITELVIGNE 1007
                    +T    +        G+   + +K+   E   + +   + +  +   V   E
Sbjct: 1139 QEMLYQTQVTAFVQEPKVGETAPGFVYSEYEKEYEKEQALIRKKMAKDTVVVRTYVEDQE 1198

Query: 1008 YYFRVFSENMCGLSEDATM-TKESAVIARDGKIYKNPVYEDFDFSEAPM--FTQPLVNTY 1064
            ++   F E +    E   + T    ++  DG+     +  D   SEA    F   + N  
Sbjct: 1199 FHISSFEERLIKEIEYRIIKTTLEELLEEDGE---EKMAVDISESEAVESGFDSRIKNYR 1255

Query: 1065 AIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRM-FSNQGVCTLEIRKPSPYDGGT 1123
             + G   T +C + G P PKI W K+   I    RY+M F   G  +L I    P D G 
Sbjct: 1256 ILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPEDEGI 1315

Query: 1124 YCCKAVNDLGTVEIECKLEVKVIA 1147
            Y   A N  G      KL V+  A
Sbjct: 1316 YTAFASNIKGNAICSGKLYVEPAA 1339



 Score = 57.0 bits (136), Expect = 1e-07
 Identities = 43/167 (25%), Positives = 72/167 (43%), Gaps = 11/167 (6%)

Query: 370 TKQLEDTTAYCGERVELECEVSEDDA-NVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIE 428
           T+ L+      G     E  +S      V WF++G+ I        +I     +  L I 
Sbjct: 9   TQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKLTIP 68

Query: 429 GATKADAAEYSVMTTGGQSSAKLSVDL------KPLKILTPLTDQTVNLGKEICLKCEIS 482
             TKA++  YS+  T G   A  + +L       P   +  L   TV  G ++ L+  ++
Sbjct: 69  AVTKANSGRYSLKATNGSGQATSTAELLVKAETAPPNFVQRLQSMTVRQGSQVRLQVRVT 128

Query: 483 ENIPG---KWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDY 526
             IP    K+ ++G  +Q S   ++  +G ++ L+IA A  ED G Y
Sbjct: 129 -GIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTY 174



 Score = 56.6 bits (135), Expect = 1e-07
 Identities = 39/140 (27%), Positives = 56/140 (40%), Gaps = 9/140 (6%)

Query: 1010  FRVFSENMCGLSEDATM---TKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAI 1066
             F+   E +  +SE       T ES V  +       P+      S  P+    L +T   
Sbjct: 26314 FKSIHEKVSKISETKKSDQKTTESTVTRKTEPKAPEPI------SSKPVIVTGLQDTTVS 26367

Query: 1067  AGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCC 1126
             +   A       G P+P   W K+  AI    +Y++  ++G   LEI K    D G Y C
Sbjct: 26368 SDSVAKFAVKATGEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTC 26427

Query: 1127  KAVNDLGTVEIECKLEVKVI 1146
                N  G+V   CKL +K I
Sbjct: 26428 TVKNSAGSVSSSCKLTIKAI 26447



 Score = 56.6 bits (135), Expect = 1e-07
 Identities = 74/348 (21%), Positives = 121/348 (34%), Gaps = 77/348 (22%)

Query: 872   GKPRPELTWKKDGAEIDKN-QINIRNSETDTIIFIRKAERSHSGKYD------------- 917
             G+PRP   W KDG  I +  +  +   +    + I K + S SG Y              
Sbjct: 26380 GEPRPTAIWTKDGKAITQGGKYKLSEDKGGFFLEIHKTDTSDSGLYTCTVKNSAGSVSSS 26439

Query: 918   --LQVKVDKFVETASIDIQIIDRPGPPQIVKIED------VWGENVALTWTPP------K 963
               L +K  K  E   +  Q      P +   +++      +  E + ++          K
Sbjct: 26440 CKLTIKAIKDTEAQKVSTQKTSEITPQKKAVVQEEISQKALRSEEIKMSEAKSQEKLALK 26499

Query: 964   DDGNAAITGYTIQKADKKSMEWFTVIEHYHRTS-------------ATITELVIGNEYYF 1010
             ++ +  +    ++K+   S+E   V E   +TS             A  T++ I NE   
Sbjct: 26500 EEASKVLISEEVKKSAATSLEKSIVHEEITKTSQASEEVRTHAEIKAFSTQMSI-NEGQR 26558

Query: 1011  RVFSENMCGLSE-----------------------DATMT------KESAVIARDGKIYK 1041
              V   N+ G ++                       D T+T      ++  ++    K  +
Sbjct: 26559 LVLKANIAGATDVKWVLNGVELTNSEEYRYGVSGSDQTLTIKQASHRDEGILTCISKTKE 26618

Query: 1042  NPVYEDFDF------SEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIV 1095
               V   +D       S+AP F     +     G N    C + G P P+I W KN + I 
Sbjct: 26619 GIVKCQYDLTLSKELSDAPAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPIS 26678

Query: 1096  DDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1143
                   +  ++ V +LEIR  S  D G Y  KA N  G       L V
Sbjct: 26679 ISSNVSISRSRNVYSLEIRNASVSDSGKYTIKAKNFRGQCSATASLMV 26726



 Score = 54.7 bits (130), Expect = 5e-07
 Identities = 52/221 (23%), Positives = 77/221 (34%), Gaps = 45/221 (20%)

Query: 927  ETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWF 986
            +TA  D++++ RP P      E  W             DG   +  YT +          
Sbjct: 1426 QTARFDLKVVGRPMP------ETFWFH-----------DGQQIVNDYTHK---------- 1458

Query: 987  TVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYE 1046
             VI+     S  I      +   + V ++N  G S  + +    AV              
Sbjct: 1459 VVIKEDGTQSLIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAV-------------- 1504

Query: 1047 DFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDD--PRYRMFS 1104
              +    PMF + L N     G    +     GNP P I W+KN   IV    P+ R+  
Sbjct: 1505 --EHQVKPMFVEKLKNVNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEG 1562

Query: 1105 NQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVKV 1145
             +G   L+I      D   Y   A+N  G     CK+ V+V
Sbjct: 1563 TKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEV 1603



 Score = 51.2 bits (121), Expect = 6e-06
 Identities = 56/305 (18%), Positives = 122/305 (40%), Gaps = 22/305 (7%)

Query: 849   PRHLKQTYIRRVGEAVNLVIPFQ--GKPRPELTWKKDGAEID-KNQINIRNSETDTIIFI 905
             P  + Q   + + E  N++   +  G+P PE+ W K+   I   + ++I  S     + I
Sbjct: 26637 PAFISQPRSQNINEGQNVLFTCEISGEPSPEIEWFKNNLPISISSNVSISRSRNVYSLEI 26696

Query: 906   RKAERSHSGKYDLQVKVDKFVETASIDIQIIDR-PGPPQIVKIEDVWGENVALTWTPPKD 964
             R A  S SGKY ++ K  +   +A+  + ++     P + V +      ++  +++    
Sbjct: 26697 RNASVSDSGKYTIKAKNFRGQCSATASLMVLPLVEEPSREVVLRTSGDTSLQGSFSSQSV 26756

Query: 965   DGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDA 1024
               +A+    +       S    T ++    ++ +++ +    E +  + S +  G+S   
Sbjct: 26757 QMSASKQEASFSSFSSSSASSMTEMKFASMSAQSMSSM---QESFVEMSSSSFMGISNMT 26813

Query: 1025  TMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAI-AGYNATLNCSVRGNPKP 1083
              +   ++ + + G                P   + L +  +I  G   T+ C+  G P P
Sbjct: 26814 QLESSTSKMLKAG------------IRGIPPKIEALPSDISIDEGKVLTVACAFTGEPTP 26861

Query: 1084  KITWM--KNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKL 1141
             ++TW     K+   +  R+ + +   + TL I      DGG Y     N+ G+      +
Sbjct: 26862 EVTWSCGGRKIHSQEQGRFHIENTDDLTTLIIMDVQKQDGGLYTLSLGNEFGSDSATVNI 26921

Query: 1142  EVKVI 1146
              ++ I
Sbjct: 26922 HIRSI 26926



 Score = 49.7 bits (117), Expect = 2e-05
 Identities = 96/424 (22%), Positives = 163/424 (38%), Gaps = 79/424 (18%)

Query: 739  PLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLID 798
            PLA+     LL  +   +  +     PPD I  +  +   ++   E      V  +DL+ 
Sbjct: 3968 PLALEEKQVLLKEEHSDNVVM-----PPDQIIESKREPVAIKKVQE------VQGRDLLS 4016

Query: 799  KTKFTITGLPTDAKIFVRV---KAVNAAGASE-PKYYSQPILVKEIIEPPKIRI---PRH 851
            K    ++G+P + ++ +++   +A+ AA ASE P  +S+ +   E +E   + I   PRH
Sbjct: 4017 KESL-LSGIPEEQRLNLKIQICRALQAAVASEQPGLFSEWLRNIEKVEVEAVNITQEPRH 4075

Query: 852  LKQTYI----RRVGEAVNLVIPFQGKPRPELTWKKDGA--EIDKNQINIRNSETDTIIFI 905
            +   Y+    + V E V ++I         L  +   A   I   +I+I  +E   I   
Sbjct: 4076 IMCMYLVTSAKSVTEEVTIIIEDVDPQMANLKMELRDALCAIIYEEIDILTAEGPRI--- 4132

Query: 906  RKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVA-----LTWT 960
                     K  LQ ++D F  +  ++           ++  E+V   NV      L  T
Sbjct: 4133 -----QQGAKTSLQEEMDSFSGSQKVEPITEPEVESKYLISTEEVSYFNVQSRVKYLDAT 4187

Query: 961  PPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGL 1020
            P      +A+       +D+K  E     E    +S+                     G 
Sbjct: 4188 PVTKGVASAVV------SDEKQDESLKPSEEKEESSSE-------------------SGT 4222

Query: 1021 SEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGN 1080
             E AT+  + A    +G + K          + PM   PLV+T +  G    L  S+  N
Sbjct: 4223 EEVATVKIQEA----EGGLIKE---------DGPMIHTPLVDTVSEEGDIVHLTTSIT-N 4268

Query: 1081 PKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDG-GTYCCKAVNDLGTVEIEC 1139
             K ++ W      +  D +++   +Q   TL I K +  D  G Y C+A+ND G      
Sbjct: 4269 AK-EVNWYFENKLVPSDEKFKCLQDQNTYTLVIDKVNTEDHQGEYVCEALNDSGKTATSA 4327

Query: 1140 KLEV 1143
            KL V
Sbjct: 4328 KLTV 4331



 Score = 48.9 bits (115), Expect = 3e-05
 Identities = 59/283 (20%), Positives = 97/283 (34%), Gaps = 70/283 (24%)

Query: 861  GEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQV 920
            GE+V L     G P P +TW ++  +I+                                
Sbjct: 911  GESVTLECHISGYPSPTVTWYREDYQIE-------------------------------- 938

Query: 921  KVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADK 980
                    +SID QI  + G  +++  E    ++   T +   + G  + + Y   +   
Sbjct: 939  --------SSIDFQITFQSGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQ--- 987

Query: 981  KSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIY 1040
                   V E + + +  +TE     E   + F E+   +  D ++T+E A        Y
Sbjct: 988  -------VSEEFEKETTAVTEKFTTEE---KRFVESRDVVMTDTSLTEEQAGPGEPAAPY 1037

Query: 1041 KNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRY 1100
                            T+P+V    + G +    C V GNPKP + W K+ V +    RY
Sbjct: 1038 --------------FITKPVVQKL-VEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRY 1082

Query: 1101 RMFSNQ--GVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKL 1141
            ++  N+  G C L I      D G Y     N  G       L
Sbjct: 1083 KVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL 1125



 Score = 48.9 bits (115), Expect = 3e-05
 Identities = 81/404 (20%), Positives = 150/404 (37%), Gaps = 60/404 (14%)

Query: 291  KGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVT 350
            +G   RF   ++   L+V WY   ++I+PS  +          L I      D+  Y   
Sbjct: 3312 EGQPARFQCRVSGTDLKVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFV 3371

Query: 351  AGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGP 410
            A +        V +        LE   +   ER+E E E+   + +  +    EE +   
Sbjct: 3372 ASNA-------VGQVSSTANLSLEAPESILHERIEQEIEMEMKEFSSSFLSAEEEGLHSA 3424

Query: 411  KSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVN 470
            + +   ++     +L          +E  V  T   S  + +  +     +  +++  ++
Sbjct: 3425 ELQLS-KINETLELL----------SESPVYPTKFDSEKEGTGPI----FIKEVSNADIS 3469

Query: 471  LGKEICLKCEISENIPG---KWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYV 527
            +G    L   +   IP    +W  NG+ +  S   K V  G  H L+I     EDEG+Y 
Sbjct: 3470 MGDVATLSVTVI-GIPKPKIQWFFNGVLLTPSADYKFVFDGDDHSLIILFTKLEDEGEYT 3528

Query: 528  -FAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRL---------------- 570
              A + Y  T+ +    I+      +G     T + +A +  +L                
Sbjct: 3529 CMASNDYGKTICSAYLKINSKG---EGHKDTETESAVAKSLEKLGGPCPPHFLKELKPIR 3585

Query: 571  ---------EIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGV 621
                     E  + GEP P   W + +K +          +   S T +++  +R+DSG+
Sbjct: 3586 CAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFIVNDPQREDSGL 3645

Query: 622  YHINLKNEAGEAHASIKVKVV----DFPDPPV-APTVTEVGDDW 660
            Y    +N  GE+  + ++ V+    D  D P  A +  E  +D+
Sbjct: 3646 YICKAENMLGESTCAAELLVLLEDTDMTDTPCKAKSTPEAPEDF 3689



 Score = 47.4 bits (111), Expect = 8e-05
 Identities = 28/96 (29%), Positives = 44/96 (45%), Gaps = 2/96 (2%)

Query: 1051 SEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDD--PRYRMFSNQGV 1108
            ++AP FTQPL +   + G  AT    + G P P+++W ++   I     P  ++  + G 
Sbjct: 3    TQAPTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGR 62

Query: 1109 CTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVK 1144
              L I   +  + G Y  KA N  G      +L VK
Sbjct: 63   AKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVK 98



 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 36/105 (34%), Positives = 48/105 (45%), Gaps = 4/105 (3%)

Query: 537 LPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSG 596
           +PA V +   P  ++ GL     VTVI G  + LE  ISG P P   W R D  I E S 
Sbjct: 886 VPAPVEIPVTPPTLVSGL---KNVTVIEGESVTLECHISGYPSPTVTWYREDYQI-ESSI 941

Query: 597 RIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKV 641
             +       + L+I  A  +DSG +  +  NEAG    S  + V
Sbjct: 942 DFQITFQSGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAV 986



 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 29/93 (31%), Positives = 42/93 (45%), Gaps = 3/93 (3%)

Query: 1054  PMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIV---DDPRYRMFSNQGVCT 1110
             P FT PL N  A  G N     ++  +P+P +TW K+   I    +D +Y   S++G+  
Sbjct: 25193 PEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQ 25252

Query: 1111  LEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1143
             L I   +  D   Y   A N  G    + KL V
Sbjct: 25253 LTINSVTTDDDAEYTVVARNKYGEDSCKAKLTV 25285



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 34/107 (31%), Positives = 47/107 (43%), Gaps = 4/107 (3%)

Query: 1041 KNPVYEDFDFSE----APMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVD 1096
            ++PVY     SE     P+F + + N     G  ATL+ +V G PKPKI W  N V +  
Sbjct: 3440 ESPVYPTKFDSEKEGTGPIFIKEVSNADISMGDVATLSVTVIGIPKPKIQWFFNGVLLTP 3499

Query: 1097 DPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1143
               Y+   +    +L I      D G Y C A ND G       L++
Sbjct: 3500 SADYKFVFDGDDHSLIILFTKLEDEGEYTCMASNDYGKTICSAYLKI 3546



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 25/93 (26%), Positives = 42/93 (45%)

Query: 1053 APMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLE 1112
            AP+  + +       G+ A   C ++  P  +  W K    I +  +  + S++ + +LE
Sbjct: 4336 APVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLE 4395

Query: 1113 IRKPSPYDGGTYCCKAVNDLGTVEIECKLEVKV 1145
            I +    D G Y CKA N+ G+V     L V V
Sbjct: 4396 ILRTQVVDCGEYTCKASNEYGSVSCTATLTVTV 4428



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 30/96 (31%), Positives = 39/96 (40%), Gaps = 3/96 (3%)

Query: 1054 PMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSN-QGVCTLE 1112
            P F + L       G  A    +V G P P +TW K    +     Y +  N  G  T  
Sbjct: 3575 PHFLKELKPIRCAQGLPAIFEYTVVGEPAPTVTWFKENKQLCTSVYYTIIHNPNGSGTFI 3634

Query: 1113 IRKPSPYDGGTYCCKAVNDLGTVEIECKLEVKVIAQ 1148
            +  P   D G Y CKA N LG  E  C  E+ V+ +
Sbjct: 3635 VNDPQREDSGLYICKAENMLG--ESTCAAELLVLLE 3668



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 29/100 (29%), Positives = 49/100 (49%), Gaps = 5/100 (5%)

Query: 939   PGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEH--YHRTS 996
             P  P    + +V  ++  +TW  P D G   IT Y ++K +  S  W  V +   +  T 
Sbjct: 10515 PDAPDQPIVTEVTKDSALVTWNKPHDGGKP-ITNYILEKRETMSKRWARVTKDPIHPYTK 10573

Query: 997   ATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARD 1036
               + +L+ G +Y FRV +EN  G+ + +  +K   V A+D
Sbjct: 10574 FRVPDLLEGCQYEFRVSAENEIGIGDPSPPSK--PVFAKD 10611



 Score = 45.1 bits (105), Expect = 4e-04
 Identities = 120/582 (20%), Positives = 208/582 (35%), Gaps = 92/582 (15%)

Query: 341  MTDDSEYYVTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDA-NVKW 399
            MTD S     AG  + +   F+ +P  +V K +E      G  V   C+V  +   +V W
Sbjct: 1018 MTDTSLTEEQAGPGEPAAPYFITKP--VVQKLVE------GGSVVFGCQVGGNPKPHVYW 1069

Query: 400  FKNGEEIIPGPKSRYRIRVEGKKHI----LIIEGATKADAAEYSVMTTG--GQSSAKLSV 453
             K+G  +  G    YR +V   K      L+I      DA EY+++     G++SA  S+
Sbjct: 1070 KKSGVPLTTG----YRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL 1125

Query: 454  DLKPLKILTPLTDQTVNLGKEICL---KCEISENIPGKWTKNGLPVQESDRLKVVHKGRI 510
              +    L   + Q +    ++     + ++ E  PG +  +    +      ++ K   
Sbjct: 1126 LEEADYELLMKSQQEMLYQTQVTAFVQEPKVGETAPG-FVYSEYEKEYEKEQALIRKKMA 1184

Query: 511  HKLVIANALTEDEGDYVFAPDA----------YNVTLPAKVHVIDPPKIILD-------- 552
               V+     ED+  ++ + +              TL   +      K+ +D        
Sbjct: 1185 KDTVVVRTYVEDQEFHISSFEERLIKEIEYRIIKTTLEELLEEDGEEKMAVDISESEAVE 1244

Query: 553  -GLDAD-NTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDS-STL 609
             G D+      ++ G  +     +SG P PK  W +  K I  G  R + +   D  ++L
Sbjct: 1245 SGFDSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGE-RYQMDFLQDGRASL 1303

Query: 610  VIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPA 669
             I +   +D G+Y     N  G A  S K+ V      P AP    +G    I   EP  
Sbjct: 1304 RIPVVLPEDEGIYTAFASNIKGNAICSGKLYV-----EPAAP----LGAPTYIPTLEP-- 1352

Query: 670  YDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISK 729
                       + R +  S R +  +          P +M        R+     +  + 
Sbjct: 1353 -----------VSRIRSLSPRSVSRSPIRMSPARMSPARMSPARMSPARMSPGRRLEETD 1401

Query: 730  PSMPSRPFVPLAVTSPPTLLTVDSVT---DTTVTMRWRPPD---HIGAAGLDGYVLEYCF 783
             S   R + P+ V  P +   ++  T   D  V  R  P     H G   ++ Y  +   
Sbjct: 1402 ESQLERLYKPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVI 1461

Query: 784  --EGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEII 841
              +GT+  I+      D  ++T+              A N AG S     S  + V+ + 
Sbjct: 1462 KEDGTQSLIIVPATPSDSGEWTVV-------------AQNRAGRSS---ISVILTVEAVE 1505

Query: 842  EPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKD 883
               K      LK   I+  G  + + +   G P P++ W K+
Sbjct: 1506 HQVKPMFVEKLKNVNIKE-GSRLEMKVRATGNPNPDIVWLKN 1546



 Score = 44.7 bits (104), Expect = 5e-04
 Identities = 62/284 (21%), Positives = 105/284 (36%), Gaps = 51/284 (17%)

Query: 876  PELT--WKKDGAEID-KNQINIRNSETDTIIFIRKAERSHSGKYDL----QVKVDK-FVE 927
            P++T  W KD  E+   ++I I+  +    + I     S +GKY +     V   K FVE
Sbjct: 3038 PDITVQWMKDDQELQITDRIKIQKEKYVHRLLIPSTRMSDAGKYTVVAGGNVSTAKLFVE 3097

Query: 928  TASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNA------AITGYTIQKADKK 981
               + I+ I +       +++ +  +   + +   +DD +A          + +Q+  K 
Sbjct: 3098 GRDVRIRSIKK-------EVQVIEKQRAVVEFEVNEDDVDAHWYKDGIEINFQVQERHK- 3149

Query: 982  SMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYK 1041
                + V    HR   + T      EY F V   N   ++                 +Y 
Sbjct: 3150 ----YVVERRIHRMFISETRQSDAGEYTF-VAGRNRSSVT-----------------LYV 3187

Query: 1042 NPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYR 1101
            N         E P   Q L      +G  A     + G P+PKI+W K +  +    + +
Sbjct: 3188 NA-------PEPPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCK 3240

Query: 1102 MFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVKV 1145
               +    TL + +  P D   Y C+A ND G       L V+V
Sbjct: 3241 FLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEV 3284



 Score = 44.3 bits (103), Expect = 7e-04
 Identities = 29/98 (29%), Positives = 51/98 (52%), Gaps = 1/98 (1%)

Query: 559 TVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDD 618
           ++TV  G+++RL++ ++G P P   + R D A ++ S   +     D  +L+I  A  +D
Sbjct: 112 SMTVRQGSQVRLQVRVTGIPTPVVKFYR-DGAEIQSSLDFQISQEGDLYSLLIAEAYPED 170

Query: 619 SGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEV 656
           SG Y +N  N  G A ++ ++ V    + P   T T V
Sbjct: 171 SGTYSVNATNSVGRATSTAELLVQGEEEVPAKKTKTIV 208



 Score = 44.3 bits (103), Expect = 7e-04
 Identities = 64/320 (20%), Positives = 110/320 (34%), Gaps = 40/320 (12%)

Query: 340   QMTDDSEYYVTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEV-SEDDANVK 398
             Q T + +Y      E  S + F  +    +T ++      CG+       V S+  A VK
Sbjct: 25856 QKTSERKY------EVLSQQPFTLDHAPRITLRMRSHRVPCGQNTRFILNVQSKPTAEVK 25909

Query: 399   WFKNGEEIIPGPKSRYRIRVEGKKHILIIEGAT-------------KADAAEYSVM-TTG 444
             W+ NG E+    K  Y     G   + I++  T             K +A++Y+ +  TG
Sbjct: 25910 WYHNGVELQESSKIHYT-NTSGVLTLEILDCHTDDSGTYRAVCTNYKGEASDYATLDVTG 25968

Query: 445   GQSSAKLSV---DLKPLKILTPLTDQTVNLGKEICLKCEISENIPGKWTKNGLPVQESDR 501
             G  +   S    +  P  +   LT              E+  +   +  K+ +       
Sbjct: 25969 GDYTTYASQRRDEEVPRSVFPELTRTEAYAVSSFKKTSEMEASSSVREVKSQMTETRESL 26028

Query: 502   LKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVT 561
                 H       + + AL E   +          TL A++            L    ++T
Sbjct: 26029 SSYEHSASAE--MKSAALEEKSLEEKSTTRKIKTTLAARI------------LTKPRSMT 26074

Query: 562   VIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGV 621
             V  G   R      GEP P   W R  + ++  S R +  +    ST  I   +  D G 
Sbjct: 26075 VYEGESARFSCDTDGEPVPTVTWLRKGQ-VLSTSARHQVTTTKYKSTFEISSVQASDEGN 26133

Query: 622   YHINLKNEAGEAHASIKVKV 641
             Y + ++N  G+  A   + +
Sbjct: 26134 YSVVVENSEGKQEAEFTLTI 26153



 Score = 43.9 bits (102), Expect = 9e-04
 Identities = 94/440 (21%), Positives = 160/440 (36%), Gaps = 71/440 (16%)

Query: 271  REEKKSAAFAKILDPAYQVDKGGRVRFVVELAD-PKLEVKWYKNGQEIRPSTKYIFEHKG 329
            ++EK+        +P  +V +G   RF   +   P+ +V WY NGQ IR S ++   + G
Sbjct: 1789 QKEKQKPDIVLYPEPV-RVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRVRYDG 1847

Query: 330  CQRILFINNCQMTDDSEYYVTAG------DEKCSTELFVREP------------------ 365
                L I +C+  D  E  VTA       + K   E+  RE                   
Sbjct: 1848 I-HYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQREDFRSVLRRAPEPRPEFHVH 1906

Query: 366  --------------PIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGE-----EI 406
                          P+  T+  E       ER+  E    E +     FK        E 
Sbjct: 1907 EPGKLQFEVQKVDRPVDTTETKEVVKLKRAERITHEKVPEESEELRSKFKRRTEEGYYEA 1966

Query: 407  IPGPKSRYRIRVEGKKHIL-------------IIEGATKADAAEYSV-MTTGGQSSAKLS 452
            I   + + R + E  + +L             + E   KA A E  + + T      +LS
Sbjct: 1967 ITAVELKSRKKDESYEELLRKTKDELLHWTKELTEEEKKALAEEGKITIPTFKPDKIELS 2026

Query: 453  VDLKPLKILTPLTDQTVNLGKEICLKCEI--SENIPGKWTKNGLPVQESDRLK-VVHKGR 509
              ++  KI   +  QTV  G +   +  +    +   +W KNG+ ++ SDR+     +  
Sbjct: 2027 PSMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDN 2086

Query: 510  IHKLVIANALTEDEGDYVFAPDAYNVTLPAKVH---VIDPPKIILDGLDADNTVTVIAGN 566
            + +LVI +   ED    +    A N+      H   ++   ++I    +  + V      
Sbjct: 2087 VCELVIRDVTAEDSASIMV--KAINIAGETSSHAFLLVQAKQLITFTQELQDVVAKEKDT 2144

Query: 567  KLRLEIPISGEPPPKAMWSRGDKAIMEGSG-RIRTE-SYPDSSTLVIDIAERDDSGVYHI 624
                E   S EP  K  W +    + EG   R+ ++      S L ID ++ +D     +
Sbjct: 2145 MATFECETS-EPFVKVKWYKDGMEVHEGDKYRMHSDRKVHFLSILTIDTSDAEDYSCVLV 2203

Query: 625  NLKNEAGEAHASIKVKVVDF 644
              +N    A   ++  VV+F
Sbjct: 2204 EDENVKTTAKLIVEGAVVEF 2223



 Score = 43.9 bits (102), Expect = 9e-04
 Identities = 26/79 (32%), Positives = 37/79 (46%), Gaps = 1/79 (1%)

Query: 1066 IAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYC 1125
            + G  A   C V G P+PK+ W  N   I    R+R+    G+  L+I     YD G   
Sbjct: 1807 LEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRV-RYDGIHYLDIVDCKSYDTGEVK 1865

Query: 1126 CKAVNDLGTVEIECKLEVK 1144
              A N  G +E + KLE++
Sbjct: 1866 VTAENPEGVIEHKVKLEIQ 1884



 Score = 43.9 bits (102), Expect = 9e-04
 Identities = 59/286 (20%), Positives = 102/286 (35%), Gaps = 24/286 (8%)

Query: 861   GEAVNLVIPFQGKPRPELTWKKDGAEI-DKNQINIRNSETDTIIFIRKAERSHSGKYDLQ 919
             G+    ++  Q KP  E+ W  +G E+ + ++I+  N+     + I       SG Y  +
Sbjct: 25891 GQNTRFILNVQSKPTAEVKWYHNGVELQESSKIHYTNTSGVLTLEILDCHTDDSGTY--R 25948

Query: 920   VKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKAD 979
                  +   AS D   +D  G            E V  +  P      A    Y +    
Sbjct: 25949 AVCTNYKGEAS-DYATLDVTGGDYTTYASQRRDEEVPRSVFPELTRTEA----YAVSSFK 26003

Query: 980   KKS-MEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGK 1038
             K S ME  + +       + +TE             E++      A+   +SA +     
Sbjct: 26004 KTSEMEASSSVRE---VKSQMTET-----------RESLSSYEHSASAEMKSAALEEKSL 26049

Query: 1039  IYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDP 1098
               K+   +      A + T+P   T    G +A  +C   G P P +TW++    +    
Sbjct: 26050 EEKSTTRKIKTTLAARILTKPRSMT-VYEGESARFSCDTDGEPVPTVTWLRKGQVLSTSA 26108

Query: 1099  RYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVK 1144
             R+++ + +   T EI      D G Y     N  G  E E  L ++
Sbjct: 26109 RHQVTTTKYKSTFEISSVQASDEGNYSVVVENSEGKQEAEFTLTIQ 26154



 Score = 43.5 bits (101), Expect = 0.001
 Identities = 61/263 (23%), Positives = 104/263 (39%), Gaps = 35/263 (13%)

Query: 286   AYQVDKGGRVRFVVEL-ADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDD 344
             +++V  G   RF++ + + P  EVKWY NG E++ S+K  + +      L I +C  TDD
Sbjct: 25885 SHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESSKIHYTNTSGVLTLEILDCH-TDD 25943

Query: 345   SEYY------------------VTAGD-EKCSTELFVREPPIMVTKQLEDTTAYCGERVE 385
             S  Y                  VT GD    +++    E P  V  +L  T AY     +
Sbjct: 25944 SGTYRAVCTNYKGEASDYATLDVTGGDYTTYASQRRDEEVPRSVFPELTRTEAYAVSSFK 26003

Query: 386   LECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGG 445
                E+ E  ++V+  K+         +  R  +   +H      + +  +A     +   
Sbjct: 26004 KTSEM-EASSSVREVKS-------QMTETRESLSSYEH----SASAEMKSAALEEKSLEE 26051

Query: 446   QSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCEI-SENIPG-KWTKNGLPVQESDRLK 503
             +S+ +        +ILT     TV  G+     C+   E +P   W + G  +  S R +
Sbjct: 26052 KSTTRKIKTTLAARILTKPRSMTVYEGESARFSCDTDGEPVPTVTWLRKGQVLSTSARHQ 26111

Query: 504   VVHKGRIHKLVIANALTEDEGDY 526
             V          I++    DEG+Y
Sbjct: 26112 VTTTKYKSTFEISSVQASDEGNY 26134



 Score = 43.1 bits (100), Expect = 0.002
 Identities = 41/170 (24%), Positives = 67/170 (39%), Gaps = 16/170 (9%)

Query: 489  WTKNGLPVQESDRLKVVHK-GRIHKLVIANALTEDEGDYVFAPD--------AYNVTLPA 539
            W  +G  +      KVV K      L+I  A   D G++             +  +T+ A
Sbjct: 1444 WFHDGQQIVNDYTHKVVIKEDGTQSLIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEA 1503

Query: 540  KVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGS-GRI 598
              H + P  +     +    V +  G++L +++  +G P P  +W +    I+     +I
Sbjct: 1504 VEHQVKPMFV-----EKLKNVNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKI 1558

Query: 599  RTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKV-VDFPDP 647
            R E     + L ID     DS  Y     N+AG      KV V V+F +P
Sbjct: 1559 RIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEVEFAEP 1608



 Score = 43.1 bits (100), Expect = 0.002
 Identities = 67/327 (20%), Positives = 116/327 (35%), Gaps = 65/327 (19%)

Query: 369   VTKQLEDTTAYCGERVELECEVSEDDAN--VKWFKNGEEIIPGPKSRYRIRVEGKKHILI 426
             V+ Q+       G  V+  C++   D +  V W+    ++    K  Y I  E    IL 
Sbjct: 25073 VSGQIMHAVGEEGGHVKYVCKIENYDQSTQVTWYFGVRQLENSEK--YEITYEDGVAILY 25130

Query: 427   IEGATKADAAEY--SVMTTGGQSSAKLSVDLK---------------------------- 456
             ++  TK D   Y   V+   G+ S+   + +K                            
Sbjct: 25131 VKDITKLDDGTYRCKVVNDYGEDSSYAELFVKGVREVYDYYCRRTMKKIKRRTDTMRLLE 25190

Query: 457   -PLKILTPLTDQTVNLGKEICLKCEISENIPGK--WTKNGLPVQESDRLKVV----HKGR 509
              P +   PL ++T  +G+ +     I+ +      W K+G  ++  D  K       KG 
Sbjct: 25191 RPPEFTLPLYNKTAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKG- 25249

Query: 510   IHKLVIANALTEDEGDYV------FAPDAYNVTLPAKVHVIDPP---------KIILDGL 554
             +++L I +  T+D+ +Y       +  D+    L   +H   PP         K +L   
Sbjct: 25250 LYQLTINSVTTDDDAEYTVVARNKYGEDSCKAKLTVTLH--PPPTDSTLRPMFKRLLANA 25307

Query: 555   DADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIA 614
             +         G  +  EI +SG PPP   W +  + +  G          D   L I   
Sbjct: 25308 ECQE------GQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALHIRDT 25361

Query: 615   ERDDSGVYHINLKNEAGEAHASIKVKV 641
               +D+G Y +   N AG       ++V
Sbjct: 25362 LPEDTGYYRVTATNTAGSTSCQAHLQV 25388



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 33/111 (29%), Positives = 46/111 (41%), Gaps = 5/111 (4%)

Query: 1028 KESAVIARDGKI----YKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKP 1083
            +E   +A +GKI    +K    E     EAP   + + +     G +A     V G P P
Sbjct: 2002 EEKKALAEEGKITIPTFKPDKIELSPSMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDP 2061

Query: 1084 KITWMKNKVAIVDDPR-YRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLG 1133
            +  W KN V I    R Y  +    VC L IR  +  D  +   KA+N  G
Sbjct: 2062 ECEWYKNGVKIERSDRIYWYWPEDNVCELVIRDVTAEDSASIMVKAINIAG 2112



 Score = 40.4 bits (93), Expect = 0.010
 Identities = 73/318 (22%), Positives = 115/318 (36%), Gaps = 33/318 (10%)

Query: 838  KEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQ-GKPRPELTWKKDGAEIDKNQINIRN 896
            K  +E   +RI    K+    +V E    V+ F+  +   +  W KDG EI+        
Sbjct: 3093 KLFVEGRDVRIRSIKKEV---QVIEKQRAVVEFEVNEDDVDAHWYKDGIEINFQVQERHK 3149

Query: 897  SETDTII---FIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGE 953
               +  I   FI +  +S +G+Y      ++   T       ++ P PPQ+++      E
Sbjct: 3150 YVVERRIHRMFISETRQSDAGEYTFVAGRNRSSVTL-----YVNAPEPPQVLQ------E 3198

Query: 954  NVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEY---YF 1010
               +T    K     A+    I    +  + W+   E    T      L  G EY     
Sbjct: 3199 LQPVTVQSGKPARFCAV----ISGRPQPKISWYKE-EQLLSTGFKCKFLHDGQEYTLLLI 3253

Query: 1011 RVFSENM----CGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAI 1066
              F E+     C    D  +   SA ++ +     +P  E   +   P    PL +T   
Sbjct: 3254 EAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMPVYP--PAIITPLQDTVTS 3311

Query: 1067 AGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCC 1126
             G  A   C V G    K++W      I     +RM   +    LEI +  P D GTY  
Sbjct: 3312 EGQPARFQCRVSGTDL-KVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTF 3370

Query: 1127 KAVNDLGTVEIECKLEVK 1144
             A N +G V     L ++
Sbjct: 3371 VASNAVGQVSSTANLSLE 3388



 Score = 40.0 bits (92), Expect = 0.013
 Identities = 44/211 (20%), Positives = 95/211 (45%), Gaps = 28/211 (13%)

Query: 270  RREEKKSAAFAKILDPAYQVD-------KGGRVRFVVELAD-PKLEVKWYKNGQEIRP-- 319
            R EE   +   ++  P + +        +G   RF +++   P  E  W+ +GQ+I    
Sbjct: 1396 RLEETDESQLERLYKPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDY 1455

Query: 320  STKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTELFV--------REPPIMVTK 371
            + K + +  G Q ++ +     +D  E+ V A +    + + V         +   M  +
Sbjct: 1456 THKVVIKEDGTQSLIIVP-ATPSDSGEWTVVAQNRAGRSSISVILTVEAVEHQVKPMFVE 1514

Query: 372  QLEDTTAYCGERVELECEVSED-DANVKWFKNGEEIIPGPKSRY-RIRVEGKK--HILII 427
            +L++     G R+E++   + + + ++ W KN + I+P    +Y +IR+EG K    L I
Sbjct: 1515 KLKNVNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVP---HKYPKIRIEGTKGEAALKI 1571

Query: 428  EGATKADAAEY--SVMTTGGQSSAKLSVDLK 456
            +     D+A Y  + +   G+ + +  V+++
Sbjct: 1572 DSTVSQDSAWYTATAINKAGRDTTRCKVNVE 1602



 Score = 39.7 bits (91), Expect = 0.017
 Identities = 25/98 (25%), Positives = 37/98 (37%)

Query: 1046  EDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSN 1105
             + F    AP  T  + +     G N     +V+  P  ++ W  N V + +  +    + 
Sbjct: 25869 QPFTLDHAPRITLRMRSHRVPCGQNTRFILNVQSKPTAEVKWYHNGVELQESSKIHYTNT 25928

Query: 1106  QGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1143
              GV TLEI      D GTY     N  G       L+V
Sbjct: 25929 SGVLTLEILDCHTDDSGTYRAVCTNYKGEASDYATLDV 25966



 Score = 39.3 bits (90), Expect = 0.022
 Identities = 58/327 (17%), Positives = 107/327 (32%), Gaps = 45/327 (13%)

Query: 861  GEAVNLVIPFQGKPRPELTWKKDGAEIDKN---QINIRNSETDTIIFIRKAERSHSGKYD 917
            G+     +   G+P PE  W  DG +I  +   ++ I+   T ++I +  A  S SG++ 
Sbjct: 1425 GQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLIIV-PATPSDSGEWT 1483

Query: 918  L--QVKVDKFVETASIDIQIIDRPGPPQIV----------------KIEDVWGENVALTW 959
            +  Q +  +   +  + ++ ++    P  V                K+      N  + W
Sbjct: 1484 VVAQNRAGRSSISVILTVEAVEHQVKPMFVEKLKNVNIKEGSRLEMKVRATGNPNPDIVW 1543

Query: 960  TPPKD------------DGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNE 1007
                D            +G        I     +   W+T     ++     T   +  E
Sbjct: 1544 LKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATA-INKAGRDTTRCKVNVE 1602

Query: 1008 YYFR--------VFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQP 1059
              F         +         E A    E   +    + ++     D +  + P F + 
Sbjct: 1603 VEFAEPEPERKLIIPRGTYRAKEIAAPELEPLHLRYGQEQWEEGDLYDKEKQQKPFFKKK 1662

Query: 1060 LVNTYAIAGYNATLNCSVR--GNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPS 1117
            L +        A   C +   G+P   + W+ +   +    R RM +  G C+L+     
Sbjct: 1663 LTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRMINEFGYCSLDYGVAY 1722

Query: 1118 PYDGGTYCCKAVNDLGTVEIECKLEVK 1144
              D G   C+A N  GT      L VK
Sbjct: 1723 SRDSGIITCRATNKYGTDHTSATLIVK 1749



 Score = 38.9 bits (89), Expect = 0.028
 Identities = 44/162 (27%), Positives = 69/162 (42%), Gaps = 13/162 (8%)

Query: 304 PKLEVKWYKNGQEIRPST--KYIFEHKGCQRILFINNCQMTDDSEYYVTA----GDEKCS 357
           P  EV W+++GQ I  ST           +  L I      +   Y + A    G    +
Sbjct: 33  PVPEVSWFRDGQVISTSTLPGVQISFSDGRAKLTIPAVTKANSGRYSLKATNGSGQATST 92

Query: 358 TELFVR---EPPIMVTKQLEDTTAYCGERVELECEVSE-DDANVKWFKNGEEIIPGPKSR 413
            EL V+    PP  V ++L+  T   G +V L+  V+      VK++++G EI       
Sbjct: 93  AELLVKAETAPPNFV-QRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEI--QSSLD 149

Query: 414 YRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDL 455
           ++I  EG  + L+I  A   D+  YSV  T     A  + +L
Sbjct: 150 FQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAEL 191



 Score = 38.1 bits (87), Expect = 0.048
 Identities = 38/173 (21%), Positives = 68/173 (39%), Gaps = 11/173 (6%)

Query: 362  VREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGK 421
            ++E   M+   L DT +  G+ V L   ++       +F+N  +++P  + +++   +  
Sbjct: 4238 IKEDGPMIHTPLVDTVSEEGDIVHLTTSITNAKEVNWYFEN--KLVPSDE-KFKCLQDQN 4294

Query: 422  KHILIIEGATKAD-AAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVN-----LGKEI 475
             + L+I+     D   EY             S  L  +K   P+  + +      LG   
Sbjct: 4295 TYTLVIDKVNTEDHQGEYVCEALNDSGKTATSAKLTVVKRAAPVIKRKIEPLEVALGHLA 4354

Query: 476  CLKCEISE--NIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDY 526
               CEI    N+  +W K G  + ESD+  +     I  L I      D G+Y
Sbjct: 4355 KFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEY 4407



 Score = 38.1 bits (87), Expect = 0.048
 Identities = 27/98 (27%), Positives = 41/98 (41%), Gaps = 3/98 (3%)

Query: 1049  DFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGV 1108
             D +  PMF + L N     G +      V G P P + W K+   +   P   +  ++G+
Sbjct: 25293 DSTLRPMFKRLLANAECQEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEII-HEGL 25351

Query: 1109  --CTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVK 1144
                 L IR   P D G Y   A N  G+   +  L+V+
Sbjct: 25352 DYYALHIRDTLPEDTGYYRVTATNTAGSTSCQAHLQVE 25389



 Score = 37.7 bits (86), Expect = 0.063
 Identities = 26/83 (31%), Positives = 34/83 (40%), Gaps = 5/83 (6%)

Query: 289   VDKGGRVRFVVELAD-PKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEY 347
             V  G  VRF   +   P    KW  +G EI+    Y  E      +L I NC   D  EY
Sbjct: 11025 VKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDEHYTVETDNFSSVLTIKNCLRRDTGEY 11084

Query: 348   YVT----AGDEKCSTELFVREPP 366
              +T    AG +  +  L V + P
Sbjct: 11085 QITVSNAAGSKTVAVHLTVLDVP 11107



 Score = 37.7 bits (86), Expect = 0.063
 Identities = 19/65 (29%), Positives = 31/65 (47%)

Query: 1084  KITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1143
             ++TW      + +  +Y +    GV  L ++  +  D GTY CK VND G      +L V
Sbjct: 25102 QVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDGTYRCKVVNDYGEDSSYAELFV 25161

Query: 1144  KVIAQ 1148
             K + +
Sbjct: 25162 KGVRE 25166



 Score = 37.0 bits (84), Expect = 0.11
 Identities = 25/94 (26%), Positives = 40/94 (42%), Gaps = 1/94 (1%)

Query: 1054 PMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYR-MFSNQGVCTLE 1112
            P+F    V+   + G  A  +  V G P P+  W  +   IV+D  ++ +    G  +L 
Sbjct: 1411 PVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLI 1470

Query: 1113 IRKPSPYDGGTYCCKAVNDLGTVEIECKLEVKVI 1146
            I   +P D G +   A N  G   I   L V+ +
Sbjct: 1471 IVPATPSDSGEWTVVAQNRAGRSSISVILTVEAV 1504



 Score = 36.2 bits (82), Expect = 0.18
 Identities = 45/250 (18%), Positives = 92/250 (36%), Gaps = 31/250 (12%)

Query: 880  WKKDGAEIDKN-QINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDR 938
            W KDG EI  + + +I+      I+ I+KA+    G+Y      DK     +++ ++I  
Sbjct: 5197 WFKDGEEIVPSPKYSIKADGLRRILKIKKADLKDKGEYVCDCGTDKTKANVTVEARLIKV 5256

Query: 939  PGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSAT 998
              P   V++      +  +  + P   G   + G  +                   T++ 
Sbjct: 5257 EKPLYGVEVFVGETAHFEIELSEPDVHGQWKLKGQPL-------------------TASP 5297

Query: 999  ITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQ 1058
              E++   + +  +      G++ + +    +A  A + K+ + P+          +F  
Sbjct: 5298 DCEIIEDGKKHILILHNCQLGMTGEVSFQAANAKSAANLKVKELPL----------IFIT 5347

Query: 1059 PLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSP 1118
            PL +        A   C V   PK    W+K    I  D R+ +  +    ++ I+  + 
Sbjct: 5348 PLSDVKVFEKDEAKFECEVSREPK-TFRWLKGTQEITGDDRFELIKDGTKHSMVIKSAAF 5406

Query: 1119 YDGGTYCCKA 1128
             D   Y  +A
Sbjct: 5407 EDEAKYMFEA 5416



 Score = 36.2 bits (82), Expect = 0.18
 Identities = 39/146 (26%), Positives = 56/146 (38%), Gaps = 11/146 (7%)

Query: 301   LADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTEL 360
             L  PK  V W K  Q ++ + +  FE      IL IN C  +D   Y +TA +       
Sbjct: 14593 LGRPKPTVTWKKGDQILKQTQRVNFETTATSTILNINECVRSDSGPYPLTARN------- 14645

Query: 361   FVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEG 420
              V E   ++T Q+ D        ++ + EVS D     W    E     P S Y + +  
Sbjct: 14646 IVGEVGDVITIQVHDIPGPPTGPIKFD-EVSSDFVTFSW-DPPENDGGVPISNYVVEMRQ 14703

Query: 421   KKHILIIEGATKADAAEYSV--MTTG 444
                   +E AT      Y    +TTG
Sbjct: 14704 TDSTTWVELATTVIRTTYKATRLTTG 14729



 Score = 35.8 bits (81), Expect = 0.24
 Identities = 25/91 (27%), Positives = 42/91 (46%), Gaps = 1/91 (1%)

Query: 559 TVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDS-STLVIDIAERD 617
           +V V+ G+    E  ISG P P+  W R  + I   +      S+ D  + L I    + 
Sbjct: 14  SVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKLTIPAVTKA 73

Query: 618 DSGVYHINLKNEAGEAHASIKVKVVDFPDPP 648
           +SG Y +   N +G+A ++ ++ V     PP
Sbjct: 74  NSGRYSLKATNGSGQATSTAELLVKAETAPP 104



 Score = 35.8 bits (81), Expect = 0.24
 Identities = 23/89 (25%), Positives = 34/89 (38%), Gaps = 2/89 (2%)

Query: 561   TVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSG--RIRTESYPDSSTLVIDIAERDD 618
             T   G  +R  + I+  P P   W +  + I  G    +   ES      L I+    DD
Sbjct: 25203 TAYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDKKYTFESDKGLYQLTINSVTTDD 25262

Query: 619   SGVYHINLKNEAGEAHASIKVKVVDFPDP 647
                Y +  +N+ GE     K+ V   P P
Sbjct: 25263 DAEYTVVARNKYGEDSCKAKLTVTLHPPP 25291



 Score = 35.0 bits (79), Expect = 0.41
 Identities = 23/91 (25%), Positives = 37/91 (40%)

Query: 1054 PMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEI 1113
            P F Q L +     G    L   V G P P + + ++   I     +++     + +L I
Sbjct: 104  PNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLI 163

Query: 1114 RKPSPYDGGTYCCKAVNDLGTVEIECKLEVK 1144
             +  P D GTY   A N +G      +L V+
Sbjct: 164  AEAYPEDSGTYSVNATNSVGRATSTAELLVQ 194



 Score = 35.0 bits (79), Expect = 0.41
 Identities = 27/90 (30%), Positives = 39/90 (43%), Gaps = 4/90 (4%)

Query: 1054 PMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEI 1113
            P FT  L +  A+     TL C V  +   K  W K+   IV  P+Y + ++     L+I
Sbjct: 5166 PYFTVKLHDKTAVEKDEITLKCEVSKDVPVK--WFKDGEEIVPSPKYSIKADGLRRILKI 5223

Query: 1114 RKPSPYDGGTYCCKAVND--LGTVEIECKL 1141
            +K    D G Y C    D     V +E +L
Sbjct: 5224 KKADLKDKGEYVCDCGTDKTKANVTVEARL 5253



 Score = 33.9 bits (76), Expect = 0.91
 Identities = 27/119 (22%), Positives = 51/119 (42%), Gaps = 11/119 (9%)

Query: 418 VEGKKHILIIEGATKADAAEYSVM-------TTGGQSSAKLSVDLKPLKILTPLTDQTVN 470
           VE KK + +    T      + V+       T   +  A + + + P  +++ L + TV 
Sbjct: 850 VEVKKEVGVSITGTTVREERFEVLHGREAKVTETARVPAPVEIPVTPPTLVSGLKNVTVI 909

Query: 471 LGKEICLKCEISENIPGK---WTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDY 526
            G+ + L+C IS   P     W +    ++ S   ++  +  I +L+I  A  ED G +
Sbjct: 910 EGESVTLECHIS-GYPSPTVTWYREDYQIESSIDFQITFQSGIARLMIREAFAEDSGRF 967



 Score = 33.9 bits (76), Expect = 0.91
 Identities = 25/77 (32%), Positives = 40/77 (51%), Gaps = 8/77 (10%)

Query: 3    EPTKKEENEVPA-PAPPPEEPSKEKEAGTTPAKDEEEVSPPSALP---PGLGSRALERK- 57
            EP K E+ + PA P PPP +P +E E  T   K E ++  P+ +P   P +   A E K 
Sbjct: 4468 EPKKLEKVKKPAVPEPPPPKPVEEVEVPTV-TKRERKIPEPTKVPEIKPAIPLPAPEPKP 4526

Query: 58   --DSDWTLVETPPGEEQ 72
              +++   ++ PP E +
Sbjct: 4527 KPEAEVKTIKPPPVEPE 4543



 Score = 33.5 bits (75), Expect = 1.2
 Identities = 35/140 (25%), Positives = 63/140 (45%), Gaps = 11/140 (7%)

Query: 799 KTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIR 858
           + K TI  +         +KA N +G +     +  +LVK    PP     + L+   +R
Sbjct: 62  RAKLTIPAVTKANSGRYSLKATNGSGQATS---TAELLVKAETAPPNF--VQRLQSMTVR 116

Query: 859 RVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTI--IFIRKAERSHSGKY 916
           + G  V L +   G P P + + +DGAEI ++ ++ + S+   +  + I +A    SG Y
Sbjct: 117 Q-GSQVRLQVRVTGIPTPVVKFYRDGAEI-QSSLDFQISQEGDLYSLLIAEAYPEDSGTY 174

Query: 917 DLQV--KVDKFVETASIDIQ 934
            +     V +   TA + +Q
Sbjct: 175 SVNATNSVGRATSTAELLVQ 194



 Score = 33.5 bits (75), Expect = 1.2
 Identities = 43/147 (29%), Positives = 59/147 (40%), Gaps = 10/147 (6%)

Query: 304   PKLEVKWYKNGQE-IRPSTKY-IFEHKGCQRILFINNCQMTDDSEYYVTA----GDEKCS 357
             PK  VKWY+ G+E I    KY I E KG    L I +    D + Y V A    G    +
Sbjct: 24458 PKPIVKWYRQGKEIIADGLKYRIQEFKGGYHQLIIASVTDDDATVYQVRATNQGGSVSGT 24517

Query: 358   TELFVREP-PIMVTKQLED---TTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSR 413
               L V  P  I + K LE      A  GE V ++   S     V  ++ G+++I      
Sbjct: 24518 ASLEVEVPAKIHLPKTLEGMGAVHALRGEVVSIKIPFSGKPDPVITWQKGQDLIDNNGHY 24577

Query: 414   YRIRVEGKKHILIIEGATKADAAEYSV 440
               I       ++   G  + DA  Y V
Sbjct: 24578 QVIVTRSFTSLVFPNGVERKDAGFYVV 24604



 Score = 33.1 bits (74), Expect = 1.6
 Identities = 21/96 (21%), Positives = 41/96 (42%), Gaps = 3/96 (3%)

Query: 854 QTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQ---INIRNSETDTIIFIRKAER 910
           Q+ +   G          G P PE++W +DG  I  +    + I  S+    + I    +
Sbjct: 13  QSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKLTIPAVTK 72

Query: 911 SHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVK 946
           ++SG+Y L+        T++ ++ +     PP  V+
Sbjct: 73  ANSGRYSLKATNGSGQATSTAELLVKAETAPPNFVQ 108



 Score = 33.1 bits (74), Expect = 1.6
 Identities = 19/61 (31%), Positives = 27/61 (44%), Gaps = 1/61 (1%)

Query: 1071 ATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVN 1130
            AT  C     P  K+ W K+ + + +  +YRM S++ V  L I      D   Y C  V 
Sbjct: 2146 ATFECET-SEPFVKVKWYKDGMEVHEGDKYRMHSDRKVHFLSILTIDTSDAEDYSCVLVE 2204

Query: 1131 D 1131
            D
Sbjct: 2205 D 2205



 Score = 33.1 bits (74), Expect = 1.6
 Identities = 55/256 (21%), Positives = 103/256 (40%), Gaps = 21/256 (8%)

Query: 304   PKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTA----GDEKCSTE 359
             P  ++KWY+ G+E+  S KY     G    L +   +  D+  Y   A    G+ + S++
Sbjct: 24063 PLPDIKWYRFGKELIQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEVGEVETSSK 24122

Query: 360   LFVREPPIMVT--KQLEDTTAYCGERVELE-CEVSEDDANVKWFKNGEEIIPGPKSRYRI 416
             L ++  P         E      G  + L    +      + WF +G++++   ++    
Sbjct: 24123 LLLQATPQFHPGYPLKEKYYGAVGSTLRLHVMYIGRPVPAMTWF-HGQKLLQNSENITIE 24181

Query: 417   RVEGKKHILIIEGATKADAAEYSVMTTG--GQSSAKLSVDL--KPLKILTPLTDQTVNLG 472
               E   H+++     K  A +Y V  +   G   A L V++  KP K   P+  + + L 
Sbjct: 24182 NTEHYTHLVMKNVQRKTHAGKYKVQLSNVFGTVDAILDVEIQDKPDKPTGPIVIEAL-LK 24240

Query: 473   KEICLKCEISENIPGKWTKNGL----PVQESDRLKVVHKG-RIHKLVIANALTEDEGDY- 526
                 +  +   +  G W  N +      +E    ++V     +    I N LTE+ G Y 
Sbjct: 24241 NSAVISWKPPADDGGSWITNYVVEKCEAKEGAEWQLVSSAISVTTCRIVN-LTENAGYYF 24299

Query: 527   -VFAPDAYNVTLPAKV 541
              V A + + ++ P +V
Sbjct: 24300 RVSAQNTFGISDPLEV 24315



 Score = 32.3 bits (72), Expect = 2.7
 Identities = 28/116 (24%), Positives = 51/116 (43%), Gaps = 8/116 (6%)

Query: 130  KAGKHLQLKETFERHSRVYTFEMQIIKAKDNFAGNYRCEVTYKDKFDSCSFDLEVHESTG 189
            KAG+ +   +     S  Y   ++I++ +    G Y C+ + +    SC+  L V     
Sbjct: 4372 KAGREIYESDKCSIRSSKYISSLEILRTQVVDCGEYTCKASNEYGSVSCTATLTV----- 4426

Query: 190  TTPNIDIRSAFKRSGEGQEDAGELDFSGLLKRREVKQQEEEPQVDVWELLKNAKPS 245
            T P  + +          E   E+    +L++R    +EEEP+V+  +L K  KP+
Sbjct: 4427 TVPGGEKKVRKLLPERKPEPKEEVVLKSVLRKR---PEEEEPKVEPKKLEKVKKPA 4479



 Score = 32.3 bits (72), Expect = 2.7
 Identities = 16/45 (35%), Positives = 22/45 (48%), Gaps = 3/45 (6%)

Query: 843   PPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEI 887
             PP+  +P + K  Y   VGE V   +     P P +TW K G +I
Sbjct: 25192 PPEFTLPLYNKTAY---VGENVRFGVTITVHPEPHVTWYKSGQKI 25233



 Score = 32.0 bits (71), Expect = 3.5
 Identities = 27/97 (27%), Positives = 39/97 (40%), Gaps = 5/97 (5%)

Query: 274  KKSAAFAKILDPAYQVDKGGRVRFVVELAD-PKLEVKWYKNGQEIRPSTKYIFEHKGCQR 332
            K++A   K      +V  G   +F  E+   P +  +W+K G+EI  S K          
Sbjct: 4333 KRAAPVIKRKIEPLEVALGHLAKFTCEIQSAPNVRFQWFKAGREIYESDKCSIRSSKYIS 4392

Query: 333  ILFINNCQMTDDSEYYVTAGDE----KCSTELFVREP 365
             L I   Q+ D  EY   A +E     C+  L V  P
Sbjct: 4393 SLEILRTQVVDCGEYTCKASNEYGSVSCTATLTVTVP 4429



 Score = 31.6 bits (70), Expect = 4.5
 Identities = 26/88 (29%), Positives = 33/88 (37%), Gaps = 4/88 (4%)

Query: 1059 PLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSP 1118
            PL +   I G  A L C V       + W  N   I  D R +         L I +   
Sbjct: 2404 PLKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVKGTKQRLVINRTHA 2463

Query: 1119 YDGGTYCCKAVNDLGTVEIECKLEVKVI 1146
             D G Y  K +  +G VE  C L V+ I
Sbjct: 2464 SDEGPY--KLI--VGRVETNCNLSVEKI 2487



 Score = 31.2 bits (69), Expect = 5.9
 Identities = 15/66 (22%), Positives = 30/66 (45%), Gaps = 1/66 (1%)

Query: 287   YQVDKGGRVRFVVE-LADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDS 345
             Y +  G  ++  +  +  P+  + W K+G+ ++ +T+   E      +L I      D  
Sbjct: 17824 YSIQAGEDLKIEIPVIGRPRPNISWVKDGEPLKQTTRVNVEETATSTVLHIKEGNKDDFG 17883

Query: 346   EYYVTA 351
             +Y VTA
Sbjct: 17884 KYTVTA 17889



 Score = 30.8 bits (68), Expect = 7.7
 Identities = 22/58 (37%), Positives = 28/58 (48%), Gaps = 6/58 (10%)

Query: 1    MPEPTKKEENE--VPAPAPPPEEPSKEKEAGTTPAKDEEEVSPPSALP---PGLGSRA 53
            +PEPTK  E +  +P PAP P +P  E E  T      E    P A P   P +G +A
Sbjct: 4504 IPEPTKVPEIKPAIPLPAPEP-KPKPEAEVKTIKPPPVEPEPTPIAAPVTVPVVGKKA 4560


>gi|148839296 immunoglobulin-like and fibronectin type III domain
            containing 1 [Homo sapiens]
          Length = 868

 Score =  249 bits (635), Expect = 1e-65
 Identities = 215/794 (27%), Positives = 329/794 (41%), Gaps = 52/794 (6%)

Query: 373  LEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATK 432
            L D     GE   L C ++ D     WFK+G ++    +     + +G  H L I     
Sbjct: 79   LADMEVQPGEAATLSCTLTSDLGPGTWFKDGVKLT--TQDGVIFKQDGLVHSLFITHVQG 136

Query: 433  ADAAEYSVMTTGGQSSAKLSVDLKPL-------KILTPLTDQTVNLGKEICLKCEISENI 485
              A  Y+ +    QS A L+V   P        K+  PL    V  GK + +K     ++
Sbjct: 137  TQAGRYTFVAGDQQSEATLTVQDSPTIAPDVTEKLREPL---VVKAGKPVIVKIPFQSHL 193

Query: 486  P--GKWTKNGLP-VQESDRLKVVHKGRIH-KLVIANALTEDEGDY--VFAPDAYNVTLPA 539
            P    W K+G   V  SDR   V  G  + +L + +A  +D G Y      +  +V    
Sbjct: 194  PIQAAWRKDGAEVVGSSDREAQVDLGDGYTRLCLPSAGRKDCGQYSVTLRSEGGSVQAEL 253

Query: 540  KVHVI---DPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIM---E 593
             + VI   DPP+  ++  D        AG  LR         PP+    R  +  +    
Sbjct: 254  TLQVIDKPDPPQGPMEVQDCHR-----AGVCLRWR-------PPRDNGGRTVECYVVERR 301

Query: 594  GSGR---IRTESYPDSSTLVIDIAERDDSGVYHINLK----NEAGEAHASIKVKVVD--F 644
             +GR   ++    P  ST   D A  +    Y   ++      AGEA  S ++ V     
Sbjct: 302  QAGRSTWLKVGEAPADSTTFTD-AHVEPGRKYTFRVRAVTSEGAGEALESEEILVAPEAL 360

Query: 645  PDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTF 704
            P  P AP +         + W  P   G + ILGY IER+KK S+ W  +N     E  +
Sbjct: 361  PKAPSAPAILSASSQGITLTWTAPRGPGSAHILGYLIERRKKGSNTWTAVNDQPVPERRW 420

Query: 705  EPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTD---TTVTM 761
                + +G  YE R+ AV   G  +P  PS          PP L+    VTD   T++T+
Sbjct: 421  TVADVRQGCQYEFRVTAVAPSGPGEPGPPSDAVFARDPMRPPGLVRNLQVTDRSNTSITL 480

Query: 762  RWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVN 821
             W  PD        GYV+E C   +  W+  +   +  T +T  GL      FVRV AVN
Sbjct: 481  SWAGPDTQEGDEAQGYVVELCSSDSLQWLPCHVGTVPVTTYTAKGLRPGEGYFVRVTAVN 540

Query: 822  AAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWK 881
              G S+P      +    +   PK  +    K     +VG+ V + + F+  P PE+TW 
Sbjct: 541  EGGQSQPSALDTLVQAMPVTVCPKFLVDSSTKDLLTVKVGDTVRVPVSFEAMPMPEVTWL 600

Query: 882  KDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETA-SIDIQIIDRPG 940
            KDG  + K  + +   +  T + I  A  S SG Y + ++  +  E A S  I++   P 
Sbjct: 601  KDGLPLPKRSVTV-TKDGLTQLLIPVAGLSDSGLYTVVLRTLQGKEVAHSFRIRVAACPQ 659

Query: 941  PPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATIT 1000
             P  + +++     V   W P  D+       Y +         W    +  H    T+ 
Sbjct: 660  APGPIHLQENVPGTVTAEWEPSPDEAQDVPLHYAVFTRSSAHGPWHEAADRIHTNRFTLL 719

Query: 1001 ELVIGNEYYFRVFSENMCGLSEDATMTKESAV-IARDGKIYKNPVYEDFDFSEAPMFTQP 1059
             ++ G+EY+FRV ++N  G S+ +  ++   +   RD    K P Y + D S+ P F   
Sbjct: 720  GILPGHEYHFRVVAKNELGASKPSDTSQPWCIPRQRDRFTVKAPCYREPDLSQKPRFLVG 779

Query: 1060 LVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPY 1119
            L +     G    ++C+V+G+P+P +TW KN  ++  +P        GVC+L I   SP 
Sbjct: 780  LRSHLLPQGCECCMSCAVQGSPRPHVTWFKNDRSLEGNPAVYSTDLLGVCSLTIPSVSPK 839

Query: 1120 DGGTYCCKAVNDLG 1133
            D G Y   A N LG
Sbjct: 840  DSGEYKAVAENTLG 853



 Score = 69.7 bits (169), Expect = 2e-11
 Identities = 107/489 (21%), Positives = 178/489 (36%), Gaps = 51/489 (10%)

Query: 310 WYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTELFVREPPIM- 368
           W+K+G ++      IF+  G    LFI + Q T    Y   AGD++    L V++ P + 
Sbjct: 105 WFKDGVKLTTQDGVIFKQDGLVHSLFITHVQGTQAGRYTFVAGDQQSEATLTVQDSPTIA 164

Query: 369 --VTKQL-EDTTAYCGERVELECEV-SEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHI 424
             VT++L E      G+ V ++    S       W K+G E++       ++ +      
Sbjct: 165 PDVTEKLREPLVVKAGKPVIVKIPFQSHLPIQAAWRKDGAEVVGSSDREAQVDLGDGYTR 224

Query: 425 LIIEGATKADAAEYSV--MTTGGQSSAKLSVDL--KPLKILTPLTDQTV----------- 469
           L +  A + D  +YSV   + GG   A+L++ +  KP     P+  Q             
Sbjct: 225 LCLPSAGRKDCGQYSVTLRSEGGSVQAELTLQVIDKPDPPQGPMEVQDCHRAGVCLRWRP 284

Query: 470 ---NLGKEI-CLKCEISENIPGKWTKNGLPVQESDRLKVVH--KGRIHKLVIANALTEDE 523
              N G+ + C   E  +     W K G    +S      H   GR +   +    +E  
Sbjct: 285 PRDNGGRTVECYVVERRQAGRSTWLKVGEAPADSTTFTDAHVEPGRKYTFRVRAVTSEGA 344

Query: 524 GDYVFAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIA----GNKLRLEIPISGEPP 579
           G+ + + +   +  P  +        IL       T+T  A    G+   L   I     
Sbjct: 345 GEALESEEI--LVAPEALPKAPSAPAILSASSQGITLTWTAPRGPGSAHILGYLIERRKK 402

Query: 580 PKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKV 639
               W+            +  +  P+    V D+  +     + +     +G        
Sbjct: 403 GSNTWT-----------AVNDQPVPERRWTVADV-RQGCQYEFRVTAVAPSGPGEPGPPS 450

Query: 640 KVVDFPDPPVAP------TVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMR 693
             V   DP   P       VT+  +    ++W  P    G    GY +E     S +W+ 
Sbjct: 451 DAVFARDPMRPPGLVRNLQVTDRSNTSITLSWAGPDTQEGDEAQGYVVELCSSDSLQWLP 510

Query: 694 LNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDS 753
            +      TT+  K +  G  Y VR+ AVN  G S+PS        + VT  P  L VDS
Sbjct: 511 CHVGTVPVTTYTAKGLRPGEGYFVRVTAVNEGGQSQPSALDTLVQAMPVTVCPKFL-VDS 569

Query: 754 VTDTTVTMR 762
            T   +T++
Sbjct: 570 STKDLLTVK 578



 Score = 31.6 bits (70), Expect = 4.5
 Identities = 17/70 (24%), Positives = 33/70 (47%), Gaps = 1/70 (1%)

Query: 574 ISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEA 633
           + G P P   W + D+++ EG+  + +       +L I      DSG Y    +N  G+A
Sbjct: 797 VQGSPRPHVTWFKNDRSL-EGNPAVYSTDLLGVCSLTIPSVSPKDSGEYKAVAENTLGQA 855

Query: 634 HASIKVKVVD 643
            ++  + V++
Sbjct: 856 VSTATLIVIE 865


>gi|110349721 titin isoform novex-3 [Homo sapiens]
          Length = 5604

 Score =  139 bits (350), Expect = 2e-32
 Identities = 112/414 (27%), Positives = 188/414 (45%), Gaps = 21/414 (5%)

Query: 295  VRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDE 354
            + F V +    +  KW KNG EI+ + K     K     L I N    D ++Y   AG  
Sbjct: 2986 ITFEVTVNYEGISYKWLKNGVEIKSTDKCQMRTKKLTHSLNIRNVHFGDAADYTFVAGKA 3045

Query: 355  KCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRY 414
              +  L+V    I   K ++D      +R   ECEVSE D  V+W K+ +E+      R 
Sbjct: 3046 TSTATLYVEARHIEFRKHIKDIKVLEKKRAMFECEVSEPDITVQWMKDDQEL--QITDRI 3103

Query: 415  RIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKE 474
            +I+ E   H L+I     +DA +Y+V+  G  S+AKL V+ + ++I +   +  V   + 
Sbjct: 3104 KIQKEKYVHRLLIPSTRMSDAGKYTVVAGGNVSTAKLFVEGRDVRIRSIKKEVQVIEKQR 3163

Query: 475  ICLKCEISE-NIPGKWTKNGLPV--QESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPD 531
              ++ E++E ++   W K+G+ +  Q  +R K V + RIH++ I+     D G+Y F   
Sbjct: 3164 AVVEFEVNEDDVDAHWYKDGIEINFQVQERHKYVVERRIHRMFISETRQSDAGEYTFVAG 3223

Query: 532  AYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAI 591
                ++   V+  +PP++    L     VTV +G   R    ISG P PK  W + ++ +
Sbjct: 3224 RNRSSVTLYVNAPEPPQV----LQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLL 3279

Query: 592  MEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAG----EAHASIKVKVVDFPD- 646
              G  + +        TL++  A  +D+ VY    KN+ G     A  S++V  V  PD 
Sbjct: 3280 STGF-KCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQ 3338

Query: 647  --PPVAPTVTEVGDDWCIMNWEPPAY----DGGSPILGYFIERKKKQSSRWMRL 694
              P   P +     D      +P  +     G    + ++ + KK + SR+ R+
Sbjct: 3339 EMPVYPPAIITPLQDTVTSEGQPARFQCRVSGTDLKVSWYSKDKKIKPSRFFRM 3392



 Score =  136 bits (343), Expect = 1e-31
 Identities = 105/376 (27%), Positives = 169/376 (44%), Gaps = 13/376 (3%)

Query: 272  EEKKSAAFAKILDPAYQVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQ 331
            + K+   F + L      +K     F  E ++P ++VKWYK+G E+    KY        
Sbjct: 2169 QAKQLITFTQELQDVVAKEKDTMATFECETSEPFVKVKWYKDGMEVHEGDKYRMHSDRKV 2228

Query: 332  RILFINNCQMTDDSEY-YVTAGDE--KCSTELFVREPPIMVTKQLEDTTAYCGERVELEC 388
              L I     +D  +Y  V   DE  K + +L V    +   K+L+D         ELEC
Sbjct: 2229 HFLSILTIDTSDAEDYSCVLVEDENVKTTAKLIVEGAVVEFVKELQDIEVPESYSGELEC 2288

Query: 389  EVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSS 448
             VS ++   KW+ N  E+      +Y I     +  L ++  TK D  EYS +  G +++
Sbjct: 2289 IVSPENIEGKWYHNDVEL--KSNGKYTITSRRGRQNLTVKDVTKEDQGEYSFVIDGKKTT 2346

Query: 449  AKLSVDLKPLKILTPLTDQTVNLGKEICLKCEIS-ENIPGKWTKNGLPVQESDRLKVVHK 507
             KL +  +P+ IL  L+DQ V  G  + L+ ++S E++ G W K+G  VQ SDR+ +V  
Sbjct: 2347 CKLKMKPRPIAILQGLSDQKVCEGDIVQLEVKVSLESVEGVWMKDGQEVQPSDRVHIVID 2406

Query: 508  GRIHKLVIANALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNK 567
             + H L+I +   ED G+Y F   A  ++   +V V       +D +     V VI G K
Sbjct: 2407 KQSHMLLIEDMTKEDAGNYSFTIPALGLSTSGRVSVYS-----VDVITPLKDVNVIEGTK 2461

Query: 568  LRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLK 627
              LE  +S        W   D+ I +   R++         LVI+     D G Y + + 
Sbjct: 2462 AVLECKVSVPDVTSVKWYLNDEQI-KPDDRVQAIVKGTKQRLVINRTHASDEGPYKLIVG 2520

Query: 628  NEAGEAHASI-KVKVV 642
                  + S+ K+K++
Sbjct: 2521 RVETNCNLSVEKIKII 2536



 Score =  130 bits (328), Expect = 5e-30
 Identities = 80/234 (34%), Positives = 120/234 (51%), Gaps = 8/234 (3%)

Query: 297  FVVELADPKLE-VKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEK 355
            F VEL  P ++ V+W KNG  +  + KY    KG    L I NC + D+S Y    G   
Sbjct: 2726 FTVELTHPNVKGVQWIKNGVVLESNEKYAISVKGTIYSLRIKNCAIVDESVYGFRLGRLG 2785

Query: 356  CSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYR 415
             S  L V    + + K+ +D TA     V  E  VS D   VKWF    EI P  K  +R
Sbjct: 2786 ASARLHVET--VKIIKKPKDVTALENATVAFEVSVSHDTVPVKWFHKSVEIKPSDK--HR 2841

Query: 416  IRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEI 475
            +  E K H L+++  + +DA EY+ +   GQ   K  + ++ L I   + +  V   K  
Sbjct: 2842 LVSERKVHKLMLQNISPSDAGEYTAVV--GQLECKAKLFVETLHITKTMKNIEVPETKTA 2899

Query: 476  CLKCEISE-NIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVF 528
              +CE+S  N+P  W KNG+ ++ S++ K+V +G++H+L+I N  TED  +Y F
Sbjct: 2900 SFECEVSHFNVPSMWLKNGVEIEMSEKFKIVVQGKLHQLIIMNTSTEDSAEYTF 2953



 Score =  120 bits (301), Expect = 7e-27
 Identities = 130/513 (25%), Positives = 208/513 (40%), Gaps = 41/513 (7%)

Query: 121  KGKWMDLASKAGKHLQLKETFERHSRVYTFEMQIIKAKDNFAGNYRCEVTYKDKFDSCSF 180
            KG+W+    + GKHL L       S  +   + I   K +  G Y    TYK      S 
Sbjct: 2649 KGEWL----RDGKHLPLTNNIRSESDGHKRRLIIAATKLDDIGEY----TYKVATSKTSA 2700

Query: 181  DLEVH--ESTGTTPNIDIRSAFKRSGEGQEDAGELDFSGLLKRREVKQQEEEPQVDVWEL 238
             L+V   +   T  N+ +          +     +     +K   V +  E+  + V   
Sbjct: 2701 KLKVEAVKIKKTLKNLTVTETQDAVFTVELTHPNVKGVQWIKNGVVLESNEKYAISV--- 2757

Query: 239  LKNAKPSEYEKIAFQYGITDLRGMLKRLKRMRREEKKSAAFAKILDPAYQVD--KGGRVR 296
                K + Y        I D      RL R+    +      KI+     V   +   V 
Sbjct: 2758 ----KGTIYSLRIKNCAIVDESVYGFRLGRLGASARLHVETVKIIKKPKDVTALENATVA 2813

Query: 297  FVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKC 356
            F V ++   + VKW+    EI+PS K+    +     L + N   +D  EY    G  +C
Sbjct: 2814 FEVSVSHDTVPVKWFHKSVEIKPSDKHRLVSERKVHKLMLQNISPSDAGEYTAVVGQLEC 2873

Query: 357  STELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRI 416
              +LFV    + +TK +++      +    ECEVS  +    W KNG EI    K  ++I
Sbjct: 2874 KAKLFVE--TLHITKTMKNIEVPETKTASFECEVSHFNVPSMWLKNGVEIEMSEK--FKI 2929

Query: 417  RVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEIC 476
             V+GK H LII   +  D+AEY+ +    Q SA L+V   P+ I + L D  +N  ++  
Sbjct: 2930 VVQGKLHQLIIMNTSTEDSAEYTFVCGNDQVSATLTV--TPIMITSMLKD--INAEEKDT 2985

Query: 477  LKCEISENIPG---KWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPD-- 531
            +  E++ N  G   KW KNG+ ++ +D+ ++  K   H L I N    D  DY F     
Sbjct: 2986 ITFEVTVNYEGISYKWLKNGVEIKSTDKCQMRTKKLTHSLNIRNVHFGDAADYTFVAGKA 3045

Query: 532  AYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAI 591
                TL  +   I+  K I D       + V+   +   E  +S EP     W + D+  
Sbjct: 3046 TSTATLYVEARHIEFRKHIKD-------IKVLEKKRAMFECEVS-EPDITVQWMKDDQE- 3096

Query: 592  MEGSGRIRTESYPDSSTLVIDIAERDDSGVYHI 624
            ++ + RI+ +       L+I      D+G Y +
Sbjct: 3097 LQITDRIKIQKEKYVHRLLIPSTRMSDAGKYTV 3129



 Score =  115 bits (287), Expect = 3e-25
 Identities = 101/370 (27%), Positives = 158/370 (42%), Gaps = 34/370 (9%)

Query: 291  KGGRVRFVVELAD-----------------PKLEVKWYKNGQEIRPSTKYIFEHKGCQRI 333
            +G  V FV EL D                   +E KWY N  E++ + KY    +  ++ 
Sbjct: 2263 EGAVVEFVKELQDIEVPESYSGELECIVSPENIEGKWYHNDVELKSNGKYTITSRRGRQN 2322

Query: 334  LFINNCQMTDDSEYYVTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSED 393
            L + +    D  EY      +K + +L ++  PI + + L D     G+ V+LE +VS +
Sbjct: 2323 LTVKDVTKEDQGEYSFVIDGKKTTCKLKMKPRPIAILQGLSDQKVCEGDIVQLEVKVSLE 2382

Query: 394  DANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSV 453
                 W K+G+E+   P  R  I ++ + H+L+IE  TK DA  YS        S    V
Sbjct: 2383 SVEGVWMKDGQEV--QPSDRVHIVIDKQSHMLLIEDMTKEDAGNYSFTIPALGLSTSGRV 2440

Query: 454  DLKPLKILTPLTDQTVNLGKEICLKCEIS--ENIPGKWTKNGLPVQESDRLKVVHKGRIH 511
             +  + ++TPL D  V  G +  L+C++S  +    KW  N   ++  DR++ + KG   
Sbjct: 2441 SVYSVDVITPLKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVKGTKQ 2500

Query: 512  KLVIANALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLE 571
            +LVI      DEG Y              V  I     I+ GL  D T T        +E
Sbjct: 2501 RLVINRTHASDEGPYKLIVGRVETNCNLSVEKIK----IIRGL-RDLTCTETQNVVFEVE 2555

Query: 572  IPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAG 631
            +  SG      +W+  DK I + S + + E++     L +    +DD G Y       AG
Sbjct: 2556 LSHSG---IDVLWNFKDKEI-KPSSKYKIEAHGKIYKLTVLNMMKDDEGKYTF----YAG 2607

Query: 632  EAHASIKVKV 641
            E   S K+ V
Sbjct: 2608 ENMTSGKLTV 2617



 Score =  109 bits (272), Expect = 2e-23
 Identities = 92/363 (25%), Positives = 161/363 (44%), Gaps = 18/363 (4%)

Query: 294  RVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGD 353
            R  F  E+++P + V+W K+ QE++ + +   + +     L I + +M+D  +Y V AG 
Sbjct: 3074 RAMFECEVSEPDITVQWMKDDQELQITDRIKIQKEKYVHRLLIPSTRMSDAGKYTVVAGG 3133

Query: 354  EKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSR 413
               + +LFV    + +    ++      +R  +E EV+EDD +  W+K+G EI    + R
Sbjct: 3134 NVSTAKLFVEGRDVRIRSIKKEVQVIEKQRAVVEFEVNEDDVDAHWYKDGIEINFQVQER 3193

Query: 414  YRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDL-KPLKILTPLTDQTVNLG 472
            ++  VE + H + I    ++DA EY+ +    +SS  L V+  +P ++L  L   TV  G
Sbjct: 3194 HKYVVERRIHRMFISETRQSDAGEYTFVAGRNRSSVTLYVNAPEPPQVLQELQPVTVQSG 3253

Query: 473  KEICLKCEISENIPGK--WTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVF-A 529
            K       IS     K  W K    +    + K +H G+ + L++  A  ED   Y   A
Sbjct: 3254 KPARFCAVISGRPQPKISWYKEEQLLSTGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEA 3313

Query: 530  PDAYNVTLPAKVHVIDPPKIILDGLD-----------ADNTVTVIAGNKLRLEIPISGEP 578
             + Y V   +    ++ P+++    +             +TVT   G   R +  +SG  
Sbjct: 3314 KNDYGVATTSASLSVEVPEVVSPDQEMPVYPPAIITPLQDTVT-SEGQPARFQCRVSG-T 3371

Query: 579  PPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIK 638
              K  W   DK I + S   R   + D+  L I  A  +D G Y     N  G+  ++  
Sbjct: 3372 DLKVSWYSKDKKI-KPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTFVASNAVGQVSSTAN 3430

Query: 639  VKV 641
            + +
Sbjct: 3431 LSL 3433



 Score =  107 bits (268), Expect = 5e-23
 Identities = 123/468 (26%), Positives = 198/468 (42%), Gaps = 56/468 (11%)

Query: 221  RREVKQQEEE---PQVDVWELLKNAKPSEYEKIAFQYGITDLRGMLKRLKRMRREEKKSA 277
            R + K++ EE     +   EL    K   YE++  +        +L   K +  EEKK+ 
Sbjct: 1998 RSKFKRRTEEGYYEAITAVELKSRKKDESYEELLRK----TKDELLHWTKELTEEEKKAL 2053

Query: 278  AF-AKILDPAYQVDK-----------------------GGRVRFVVELAD-PKLEVKWYK 312
            A   KI  P ++ DK                       G    F V +   P  E +WYK
Sbjct: 2054 AEEGKITIPTFKPDKIELSPSMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYK 2113

Query: 313  NGQEIRPSTK---YIFEHKGCQRILFINNCQMTDDSEYYV----TAGDEKCSTELFVREP 365
            NG +I  S +   Y  E   C+  L I +    D +   V     AG+      L V+  
Sbjct: 2114 NGVKIERSDRIYWYWPEDNVCE--LVIRDVTAEDSASIMVKAINIAGETSSHAFLLVQAK 2171

Query: 366  PIMV-TKQLEDTTAYCGERV-ELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKH 423
             ++  T++L+D  A   + +   ECE SE    VKW+K+G E+  G K  YR+  + K H
Sbjct: 2172 QLITFTQELQDVVAKEKDTMATFECETSEPFVKVKWYKDGMEVHEGDK--YRMHSDRKVH 2229

Query: 424  ILIIEGATKADAAEYS---VMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCE 480
             L I     +DA +YS   V     +++AKL V+   ++ +  L D  V       L+C 
Sbjct: 2230 FLSILTIDTSDAEDYSCVLVEDENVKTTAKLIVEGAVVEFVKELQDIEVPESYSGELECI 2289

Query: 481  IS-ENIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPA 539
            +S ENI GKW  N + ++ + +  +  +     L + +   ED+G+Y F  D    T   
Sbjct: 2290 VSPENIEGKWYHNDVELKSNGKYTITSRRGRQNLTVKDVTKEDQGEYSFVIDGKKTT--C 2347

Query: 540  KVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIR 599
            K+ +   P  IL GL       V  G+ ++LE+ +S E   + +W + D   ++ S R+ 
Sbjct: 2348 KLKMKPRPIAILQGLSDQK---VCEGDIVQLEVKVSLE-SVEGVWMK-DGQEVQPSDRVH 2402

Query: 600  TESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDP 647
                  S  L+I+   ++D+G Y   +          + V  VD   P
Sbjct: 2403 IVIDKQSHMLLIEDMTKEDAGNYSFTIPALGLSTSGRVSVYSVDVITP 2450



 Score =  105 bits (263), Expect = 2e-22
 Identities = 101/375 (26%), Positives = 158/375 (42%), Gaps = 21/375 (5%)

Query: 288  QVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEY 347
            +V +G  V+  V+++   +E  W K+GQE++PS +          +L I +    D   Y
Sbjct: 2366 KVCEGDIVQLEVKVSLESVEGVWMKDGQEVQPSDRVHIVIDKQSHMLLIEDMTKEDAGNY 2425

Query: 348  YVTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDD-ANVKWFKNGEEI 406
              T      ST   V    + V   L+D     G +  LEC+VS  D  +VKW+ N E+I
Sbjct: 2426 SFTIPALGLSTSGRVSVYSVDVITPLKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQI 2485

Query: 407  IPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTD 466
               P  R +  V+G K  L+I     +D   Y ++    +++  LSV+   +KI+  L D
Sbjct: 2486 --KPDDRVQAIVKGTKQRLVINRTHASDEGPYKLIVGRVETNCNLSVE--KIKIIRGLRD 2541

Query: 467  QTVNLGKEICLKCEISEN-IPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGD 525
             T    + +  + E+S + I   W      ++ S + K+   G+I+KL + N + +DEG 
Sbjct: 2542 LTCTETQNVVFEVELSHSGIDVLWNFKDKEIKPSSKYKIEAHGKIYKLTVLNMMKDDEGK 2601

Query: 526  YVF--APDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAM 583
            Y F    +  +  L      I  P         D TV          E+     P  K  
Sbjct: 2602 YTFYAGENMTSGKLTVAGGAISKPL-------TDQTVAESQEAVFECEV---ANPDSKGE 2651

Query: 584  WSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVD 643
            W R  K  +  +  IR+ES      L+I   + DD G Y    K    +  A +KV+ V 
Sbjct: 2652 WLRDGKH-LPLTNNIRSESDGHKRRLIIAATKLDDIGEY--TYKVATSKTSAKLKVEAVK 2708

Query: 644  FPDPPVAPTVTEVGD 658
                    TVTE  D
Sbjct: 2709 IKKTLKNLTVTETQD 2723



 Score = 77.8 bits (190), Expect = 6e-14
 Identities = 66/264 (25%), Positives = 116/264 (43%), Gaps = 27/264 (10%)

Query: 288  QVDKGGRVRFVVELADPKLEVKWYKNGQEI----RPSTKYIFEHKGCQRILFINNCQMTD 343
            QV +  R     E+ +  ++  WYK+G EI    +   KY+ E +     +FI+  + +D
Sbjct: 3157 QVIEKQRAVVEFEVNEDDVDAHWYKDGIEINFQVQERHKYVVERR--IHRMFISETRQSD 3214

Query: 344  DSEYYVTAGDEKCSTELFVREP-PIMVTKQLEDTTAYCGERVELECEVS-EDDANVKWFK 401
              EY   AG  + S  L+V  P P  V ++L+  T   G+       +S      + W+K
Sbjct: 3215 AGEYTFVAGRNRSSVTLYVNAPEPPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYK 3274

Query: 402  NGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAA--------EYSVMTTGGQSSAKL-- 451
              + +  G K ++    +G+++ L++  A   DAA        +Y V TT    S ++  
Sbjct: 3275 EEQLLSTGFKCKF--LHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEVPE 3332

Query: 452  ------SVDLKPLKILTPLTDQTVNLGKEICLKCEIS-ENIPGKWTKNGLPVQESDRLKV 504
                   + + P  I+TPL D   + G+    +C +S  ++   W      ++ S   ++
Sbjct: 3333 VVSPDQEMPVYPPAIITPLQDTVTSEGQPARFQCRVSGTDLKVSWYSKDKKIKPSRFFRM 3392

Query: 505  VHKGRIHKLVIANALTEDEGDYVF 528
                  ++L IA A  EDEG Y F
Sbjct: 3393 TQFEDTYQLEIAEAYPEDEGTYTF 3416



 Score = 63.5 bits (153), Expect = 1e-09
 Identities = 31/92 (33%), Positives = 43/92 (46%)

Query: 1054 PMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEI 1113
            P     L N   I G + TL C + G P P +TW +    I     +++    G+  L I
Sbjct: 943  PTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIESSIDFQITFQSGIARLMI 1002

Query: 1114 RKPSPYDGGTYCCKAVNDLGTVEIECKLEVKV 1145
            R+    D G + C AVN+ GTV   C L V+V
Sbjct: 1003 REAFAEDSGRFTCSAVNEAGTVSTSCYLAVQV 1034



 Score = 59.7 bits (143), Expect = 2e-08
 Identities = 74/324 (22%), Positives = 129/324 (39%), Gaps = 19/324 (5%)

Query: 836  LVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQ--GKPRPELTWKKDGAEID----- 888
            L +E   P +   P  + +  ++++ E  ++V   Q  G P+P + WKK G  +      
Sbjct: 1069 LTEEQAGPGEPAAPYFITKPVVQKLVEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRY 1128

Query: 889  KNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIE 948
            K   N +  E   +I +  A+   +G+Y + V+ +K  ET S    +++      ++K +
Sbjct: 1129 KVSYNKQTGECKLVISMTFAD--DAGEYTIVVR-NKHGET-SASASLLEEADYELLMKSQ 1184

Query: 949  DVWGENVALTWTPPKDDGNAAITGYTIQKADKK-SMEWFTVIEHYHRTSATITELVIGNE 1007
                    +T    +        G+   + +K+   E   + +   + +  +   V   E
Sbjct: 1185 QEMLYQTQVTAFVQEPKVGETAPGFVYSEYEKEYEKEQALIRKKMAKDTVVVRTYVEDQE 1244

Query: 1008 YYFRVFSENMCGLSEDATM-TKESAVIARDGKIYKNPVYEDFDFSEAPM--FTQPLVNTY 1064
            ++   F E +    E   + T    ++  DG+     +  D   SEA    F   + N  
Sbjct: 1245 FHISSFEERLIKEIEYRIIKTTLEELLEEDGE---EKMAVDISESEAVESGFDSRIKNYR 1301

Query: 1065 AIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRM-FSNQGVCTLEIRKPSPYDGGT 1123
             + G   T +C + G P PKI W K+   I    RY+M F   G  +L I    P D G 
Sbjct: 1302 ILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGERYQMDFLQDGRASLRIPVVLPEDEGI 1361

Query: 1124 YCCKAVNDLGTVEIECKLEVKVIA 1147
            Y   A N  G      KL V+  A
Sbjct: 1362 YTAFASNIKGNAICSGKLYVEPAA 1385



 Score = 57.0 bits (136), Expect = 1e-07
 Identities = 43/167 (25%), Positives = 72/167 (43%), Gaps = 11/167 (6%)

Query: 370 TKQLEDTTAYCGERVELECEVSEDDA-NVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIE 428
           T+ L+      G     E  +S      V WF++G+ I        +I     +  L I 
Sbjct: 9   TQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKLTIP 68

Query: 429 GATKADAAEYSVMTTGGQSSAKLSVDL------KPLKILTPLTDQTVNLGKEICLKCEIS 482
             TKA++  YS+  T G   A  + +L       P   +  L   TV  G ++ L+  ++
Sbjct: 69  AVTKANSGRYSLKATNGSGQATSTAELLVKAETAPPNFVQRLQSMTVRQGSQVRLQVRVT 128

Query: 483 ENIPG---KWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDY 526
             IP    K+ ++G  +Q S   ++  +G ++ L+IA A  ED G Y
Sbjct: 129 -GIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLIAEAYPEDSGTY 174



 Score = 54.7 bits (130), Expect = 5e-07
 Identities = 52/221 (23%), Positives = 77/221 (34%), Gaps = 45/221 (20%)

Query: 927  ETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWF 986
            +TA  D++++ RP P      E  W             DG   +  YT +          
Sbjct: 1472 QTARFDLKVVGRPMP------ETFWFH-----------DGQQIVNDYTHK---------- 1504

Query: 987  TVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYE 1046
             VI+     S  I      +   + V ++N  G S  + +    AV              
Sbjct: 1505 VVIKEDGTQSLIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEAV-------------- 1550

Query: 1047 DFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDD--PRYRMFS 1104
              +    PMF + L N     G    +     GNP P I W+KN   IV    P+ R+  
Sbjct: 1551 --EHQVKPMFVEKLKNVNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRIEG 1608

Query: 1105 NQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVKV 1145
             +G   L+I      D   Y   A+N  G     CK+ V+V
Sbjct: 1609 TKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEV 1649



 Score = 53.1 bits (126), Expect = 1e-06
 Identities = 30/102 (29%), Positives = 42/102 (41%)

Query: 1042 NPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYR 1101
            N   E  D    P F +PL                V G P P + W +NK  +  D R +
Sbjct: 5171 NEAIEPKDNEMPPSFIEPLTKRKVYENTTLGFIVEVEGLPVPGVKWYRNKSLLEPDERIK 5230

Query: 1102 MFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1143
            M     VC+LEI      +GG Y C AVN +G  +    +++
Sbjct: 5231 MERVGNVCSLEISNIQKGEGGEYMCHAVNIIGEAKSFANVDI 5272



 Score = 50.8 bits (120), Expect = 7e-06
 Identities = 29/85 (34%), Positives = 42/85 (49%), Gaps = 1/85 (1%)

Query: 1050 FSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAI-VDDPRYRMFSNQGV 1108
            F   P F  P+ +       +A   CSV G P P++ W K  + I  D+ +Y +   +G 
Sbjct: 5376 FEMPPRFIMPICDFKIPENSDAVFKCSVIGIPTPEVKWYKEYMCIEPDNIKYVISEEKGS 5435

Query: 1109 CTLEIRKPSPYDGGTYCCKAVNDLG 1133
             TL+IR     D  TY C+AVN +G
Sbjct: 5436 HTLKIRNVCLSDSATYRCRAVNCVG 5460



 Score = 48.9 bits (115), Expect = 3e-05
 Identities = 59/283 (20%), Positives = 97/283 (34%), Gaps = 70/283 (24%)

Query: 861  GEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQV 920
            GE+V L     G P P +TW ++  +I+                                
Sbjct: 957  GESVTLECHISGYPSPTVTWYREDYQIE-------------------------------- 984

Query: 921  KVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADK 980
                    +SID QI  + G  +++  E    ++   T +   + G  + + Y   +   
Sbjct: 985  --------SSIDFQITFQSGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQ--- 1033

Query: 981  KSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIY 1040
                   V E + + +  +TE     E   + F E+   +  D ++T+E A        Y
Sbjct: 1034 -------VSEEFEKETTAVTEKFTTEE---KRFVESRDVVMTDTSLTEEQAGPGEPAAPY 1083

Query: 1041 KNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRY 1100
                            T+P+V    + G +    C V GNPKP + W K+ V +    RY
Sbjct: 1084 --------------FITKPVVQKL-VEGGSVVFGCQVGGNPKPHVYWKKSGVPLTTGYRY 1128

Query: 1101 RMFSNQ--GVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKL 1141
            ++  N+  G C L I      D G Y     N  G       L
Sbjct: 1129 KVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL 1171



 Score = 47.4 bits (111), Expect = 8e-05
 Identities = 28/96 (29%), Positives = 44/96 (45%), Gaps = 2/96 (2%)

Query: 1051 SEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDD--PRYRMFSNQGV 1108
            ++AP FTQPL +   + G  AT    + G P P+++W ++   I     P  ++  + G 
Sbjct: 3    TQAPTFTQPLQSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGR 62

Query: 1109 CTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVK 1144
              L I   +  + G Y  KA N  G      +L VK
Sbjct: 63   AKLTIPAVTKANSGRYSLKATNGSGQATSTAELLVK 98



 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 36/105 (34%), Positives = 48/105 (45%), Gaps = 4/105 (3%)

Query: 537  LPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSG 596
            +PA V +   P  ++ GL     VTVI G  + LE  ISG P P   W R D  I E S 
Sbjct: 932  VPAPVEIPVTPPTLVSGL---KNVTVIEGESVTLECHISGYPSPTVTWYREDYQI-ESSI 987

Query: 597  RIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKV 641
              +       + L+I  A  +DSG +  +  NEAG    S  + V
Sbjct: 988  DFQITFQSGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAV 1032



 Score = 45.1 bits (105), Expect = 4e-04
 Identities = 120/582 (20%), Positives = 208/582 (35%), Gaps = 92/582 (15%)

Query: 341  MTDDSEYYVTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDA-NVKW 399
            MTD S     AG  + +   F+ +P  +V K +E      G  V   C+V  +   +V W
Sbjct: 1064 MTDTSLTEEQAGPGEPAAPYFITKP--VVQKLVE------GGSVVFGCQVGGNPKPHVYW 1115

Query: 400  FKNGEEIIPGPKSRYRIRVEGKKHI----LIIEGATKADAAEYSVMTTG--GQSSAKLSV 453
             K+G  +  G    YR +V   K      L+I      DA EY+++     G++SA  S+
Sbjct: 1116 KKSGVPLTTG----YRYKVSYNKQTGECKLVISMTFADDAGEYTIVVRNKHGETSASASL 1171

Query: 454  DLKPLKILTPLTDQTVNLGKEICL---KCEISENIPGKWTKNGLPVQESDRLKVVHKGRI 510
              +    L   + Q +    ++     + ++ E  PG +  +    +      ++ K   
Sbjct: 1172 LEEADYELLMKSQQEMLYQTQVTAFVQEPKVGETAPG-FVYSEYEKEYEKEQALIRKKMA 1230

Query: 511  HKLVIANALTEDEGDYVFAPDA----------YNVTLPAKVHVIDPPKIILD-------- 552
               V+     ED+  ++ + +              TL   +      K+ +D        
Sbjct: 1231 KDTVVVRTYVEDQEFHISSFEERLIKEIEYRIIKTTLEELLEEDGEEKMAVDISESEAVE 1290

Query: 553  -GLDAD-NTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDS-STL 609
             G D+      ++ G  +     +SG P PK  W +  K I  G  R + +   D  ++L
Sbjct: 1291 SGFDSRIKNYRILEGMGVTFHCKMSGYPLPKIAWYKDGKRIKHGE-RYQMDFLQDGRASL 1349

Query: 610  VIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPA 669
             I +   +D G+Y     N  G A  S K+ V      P AP    +G    I   EP  
Sbjct: 1350 RIPVVLPEDEGIYTAFASNIKGNAICSGKLYV-----EPAAP----LGAPTYIPTLEP-- 1398

Query: 670  YDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISK 729
                       + R +  S R +  +          P +M        R+     +  + 
Sbjct: 1399 -----------VSRIRSLSPRSVSRSPIRMSPARMSPARMSPARMSPARMSPGRRLEETD 1447

Query: 730  PSMPSRPFVPLAVTSPPTLLTVDSVT---DTTVTMRWRPPD---HIGAAGLDGYVLEYCF 783
             S   R + P+ V  P +   ++  T   D  V  R  P     H G   ++ Y  +   
Sbjct: 1448 ESQLERLYKPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVI 1507

Query: 784  --EGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEII 841
              +GT+  I+      D  ++T+              A N AG S     S  + V+ + 
Sbjct: 1508 KEDGTQSLIIVPATPSDSGEWTVV-------------AQNRAGRSS---ISVILTVEAVE 1551

Query: 842  EPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKD 883
               K      LK   I+  G  + + +   G P P++ W K+
Sbjct: 1552 HQVKPMFVEKLKNVNIKE-GSRLEMKVRATGNPNPDIVWLKN 1592



 Score = 45.1 bits (105), Expect = 4e-04
 Identities = 66/261 (25%), Positives = 110/261 (42%), Gaps = 42/261 (16%)

Query: 297  FVVELAD-PKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTA---- 351
            F+VE+   P   VKWY+N   + P  +   E  G    L I+N Q  +  EY   A    
Sbjct: 5202 FIVEVEGLPVPGVKWYRNKSLLEPDERIKMERVGNVCSLEISNIQKGEGGEYMCHAVNII 5261

Query: 352  GDEK--CSTELFVRE-------PPI----MVTKQLEDTTAY---CGERVELECEVSEDDA 395
            G+ K   + ++  +E       PP+    ++   LE TT+      + + LE E+SE D 
Sbjct: 5262 GEAKSFANVDIMPQEERVVALPPPVTHQHVMEFDLEHTTSSRTPSPQEIVLEVELSEKD- 5320

Query: 396  NVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDL 455
             VK F+   +I+  P+          K +++       +  + ++ +  G+   +L +DL
Sbjct: 5321 -VKEFEKQVKIVTVPEF-----TPDHKSMIVSLDVLPFNFVDPNMDSREGEDK-ELKIDL 5373

Query: 456  K----PLKILTPLTDQTVNLGKEICLKCEISENIPG---KWTKNGLPVQESDRLKVV--- 505
            +    P + + P+ D  +    +   KC +   IP    KW K  + + E D +K V   
Sbjct: 5374 EVFEMPPRFIMPICDFKIPENSDAVFKCSVI-GIPTPEVKWYKEYMCI-EPDNIKYVISE 5431

Query: 506  HKGRIHKLVIANALTEDEGDY 526
             KG  H L I N    D   Y
Sbjct: 5432 EKGS-HTLKIRNVCLSDSATY 5451



 Score = 44.7 bits (104), Expect = 5e-04
 Identities = 62/284 (21%), Positives = 105/284 (36%), Gaps = 51/284 (17%)

Query: 876  PELT--WKKDGAEID-KNQINIRNSETDTIIFIRKAERSHSGKYDL----QVKVDK-FVE 927
            P++T  W KD  E+   ++I I+  +    + I     S +GKY +     V   K FVE
Sbjct: 3084 PDITVQWMKDDQELQITDRIKIQKEKYVHRLLIPSTRMSDAGKYTVVAGGNVSTAKLFVE 3143

Query: 928  TASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNA------AITGYTIQKADKK 981
               + I+ I +       +++ +  +   + +   +DD +A          + +Q+  K 
Sbjct: 3144 GRDVRIRSIKK-------EVQVIEKQRAVVEFEVNEDDVDAHWYKDGIEINFQVQERHK- 3195

Query: 982  SMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYK 1041
                + V    HR   + T      EY F V   N   ++                 +Y 
Sbjct: 3196 ----YVVERRIHRMFISETRQSDAGEYTF-VAGRNRSSVT-----------------LYV 3233

Query: 1042 NPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYR 1101
            N         E P   Q L      +G  A     + G P+PKI+W K +  +    + +
Sbjct: 3234 NA-------PEPPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGFKCK 3286

Query: 1102 MFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVKV 1145
               +    TL + +  P D   Y C+A ND G       L V+V
Sbjct: 3287 FLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTSASLSVEV 3330



 Score = 44.3 bits (103), Expect = 7e-04
 Identities = 29/98 (29%), Positives = 51/98 (52%), Gaps = 1/98 (1%)

Query: 559 TVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDD 618
           ++TV  G+++RL++ ++G P P   + R D A ++ S   +     D  +L+I  A  +D
Sbjct: 112 SMTVRQGSQVRLQVRVTGIPTPVVKFYR-DGAEIQSSLDFQISQEGDLYSLLIAEAYPED 170

Query: 619 SGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEV 656
           SG Y +N  N  G A ++ ++ V    + P   T T V
Sbjct: 171 SGTYSVNATNSVGRATSTAELLVQGEEEVPAKKTKTIV 208



 Score = 44.3 bits (103), Expect = 7e-04
 Identities = 23/79 (29%), Positives = 38/79 (48%)

Query: 1068 GYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCK 1127
            G +  L C + G P+P +TW +N V +  + +++         L I+  +  D G Y C 
Sbjct: 4173 GDSIILECLISGEPQPVVTWFQNGVLLKQNQKFQFEEVNCSHQLYIKDVNSQDSGKYKCV 4232

Query: 1128 AVNDLGTVEIECKLEVKVI 1146
            A N+ G VE    L V+ +
Sbjct: 4233 AENNSGAVESVSDLTVEPV 4251



 Score = 43.9 bits (102), Expect = 9e-04
 Identities = 94/440 (21%), Positives = 160/440 (36%), Gaps = 71/440 (16%)

Query: 271  REEKKSAAFAKILDPAYQVDKGGRVRFVVELAD-PKLEVKWYKNGQEIRPSTKYIFEHKG 329
            ++EK+        +P  +V +G   RF   +   P+ +V WY NGQ IR S ++   + G
Sbjct: 1835 QKEKQKPDIVLYPEPV-RVLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRVRYDG 1893

Query: 330  CQRILFINNCQMTDDSEYYVTAG------DEKCSTELFVREP------------------ 365
                L I +C+  D  E  VTA       + K   E+  RE                   
Sbjct: 1894 I-HYLDIVDCKSYDTGEVKVTAENPEGVIEHKVKLEIQQREDFRSVLRRAPEPRPEFHVH 1952

Query: 366  --------------PIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGE-----EI 406
                          P+  T+  E       ER+  E    E +     FK        E 
Sbjct: 1953 EPGKLQFEVQKVDRPVDTTETKEVVKLKRAERITHEKVPEESEELRSKFKRRTEEGYYEA 2012

Query: 407  IPGPKSRYRIRVEGKKHIL-------------IIEGATKADAAEYSV-MTTGGQSSAKLS 452
            I   + + R + E  + +L             + E   KA A E  + + T      +LS
Sbjct: 2013 ITAVELKSRKKDESYEELLRKTKDELLHWTKELTEEEKKALAEEGKITIPTFKPDKIELS 2072

Query: 453  VDLKPLKILTPLTDQTVNLGKEICLKCEI--SENIPGKWTKNGLPVQESDRLK-VVHKGR 509
              ++  KI   +  QTV  G +   +  +    +   +W KNG+ ++ SDR+     +  
Sbjct: 2073 PSMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDPECEWYKNGVKIERSDRIYWYWPEDN 2132

Query: 510  IHKLVIANALTEDEGDYVFAPDAYNVTLPAKVH---VIDPPKIILDGLDADNTVTVIAGN 566
            + +LVI +   ED    +    A N+      H   ++   ++I    +  + V      
Sbjct: 2133 VCELVIRDVTAEDSASIMV--KAINIAGETSSHAFLLVQAKQLITFTQELQDVVAKEKDT 2190

Query: 567  KLRLEIPISGEPPPKAMWSRGDKAIMEGSG-RIRTE-SYPDSSTLVIDIAERDDSGVYHI 624
                E   S EP  K  W +    + EG   R+ ++      S L ID ++ +D     +
Sbjct: 2191 MATFECETS-EPFVKVKWYKDGMEVHEGDKYRMHSDRKVHFLSILTIDTSDAEDYSCVLV 2249

Query: 625  NLKNEAGEAHASIKVKVVDF 644
              +N    A   ++  VV+F
Sbjct: 2250 EDENVKTTAKLIVEGAVVEF 2269



 Score = 43.9 bits (102), Expect = 9e-04
 Identities = 26/79 (32%), Positives = 37/79 (46%), Gaps = 1/79 (1%)

Query: 1066 IAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYC 1125
            + G  A   C V G P+PK+ W  N   I    R+R+    G+  L+I     YD G   
Sbjct: 1853 LEGETARFRCRVTGYPQPKVNWYLNGQLIRKSKRFRV-RYDGIHYLDIVDCKSYDTGEVK 1911

Query: 1126 CKAVNDLGTVEIECKLEVK 1144
              A N  G +E + KLE++
Sbjct: 1912 VTAENPEGVIEHKVKLEIQ 1930



 Score = 43.1 bits (100), Expect = 0.002
 Identities = 41/170 (24%), Positives = 67/170 (39%), Gaps = 16/170 (9%)

Query: 489  WTKNGLPVQESDRLKVVHK-GRIHKLVIANALTEDEGDYVFAPD--------AYNVTLPA 539
            W  +G  +      KVV K      L+I  A   D G++             +  +T+ A
Sbjct: 1490 WFHDGQQIVNDYTHKVVIKEDGTQSLIIVPATPSDSGEWTVVAQNRAGRSSISVILTVEA 1549

Query: 540  KVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGS-GRI 598
              H + P  +     +    V +  G++L +++  +G P P  +W +    I+     +I
Sbjct: 1550 VEHQVKPMFV-----EKLKNVNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKI 1604

Query: 599  RTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKV-VDFPDP 647
            R E     + L ID     DS  Y     N+AG      KV V V+F +P
Sbjct: 1605 RIEGTKGEAALKIDSTVSQDSAWYTATAINKAGRDTTRCKVNVEVEFAEP 1654



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 33/111 (29%), Positives = 46/111 (41%), Gaps = 5/111 (4%)

Query: 1028 KESAVIARDGKI----YKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKP 1083
            +E   +A +GKI    +K    E     EAP   + + +     G +A     V G P P
Sbjct: 2048 EEKKALAEEGKITIPTFKPDKIELSPSMEAPKIFERIQSQTVGQGSDAHFRVRVVGKPDP 2107

Query: 1084 KITWMKNKVAIVDDPR-YRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLG 1133
            +  W KN V I    R Y  +    VC L IR  +  D  +   KA+N  G
Sbjct: 2108 ECEWYKNGVKIERSDRIYWYWPEDNVCELVIRDVTAEDSASIMVKAINIAG 2158



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 36/121 (29%), Positives = 52/121 (42%), Gaps = 16/121 (13%)

Query: 1031 AVIARDGKIYKNPVYED-----------FDFSEA---PMFTQPLVNTYAIAGYNATLNCS 1076
            AVIA+  K+  + + E+           F+F      P F + + + YA  G  A   C 
Sbjct: 5477 AVIAKKSKVTLSSLMEELVLKSNYTDSFFEFQVVEGPPRFIKGISDCYAPIGTAAYFQCL 5536

Query: 1077 VRGNPKPKITWMKNKVAIVDDPRYRM-FSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTV 1135
            VRG+P+P + W K+   +V   R+ +  S  G   L I      D G Y C A N  G  
Sbjct: 5537 VRGSPRPTVYWYKDG-KLVQGRRFTVEESGTGFHNLFITSLVKSDEGEYRCVATNKSGMA 5595

Query: 1136 E 1136
            E
Sbjct: 5596 E 5596



 Score = 42.0 bits (97), Expect = 0.003
 Identities = 27/94 (28%), Positives = 40/94 (42%), Gaps = 4/94 (4%)

Query: 1054 PMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGV----C 1109
            P FTQ L   Y + G      C +   P P++TW  N   I    R  + +   +     
Sbjct: 3504 PSFTQKLTFKYVLEGEPVVFTCRLIACPTPEMTWFHNNRPIPTGLRRIIKAESDLHHHSS 3563

Query: 1110 TLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1143
            +LEI++    D G+Y   A+N  G+ E    L V
Sbjct: 3564 SLEIKRVQDRDSGSYRLLAINSEGSAESTASLLV 3597



 Score = 42.0 bits (97), Expect = 0.003
 Identities = 23/91 (25%), Positives = 39/91 (42%)

Query: 1054 PMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEI 1113
            P F Q + +     G +    C  +G P+P +TW  N + I  +  + + S +    L +
Sbjct: 3944 PSFLQEIESQEVYEGDSCNFVCHFQGYPQPIVTWYNNDMPIPRNQNFIIHSLENYSILTL 4003

Query: 1114 RKPSPYDGGTYCCKAVNDLGTVEIECKLEVK 1144
                  + G+  C   N  GTV+    L+VK
Sbjct: 4004 SSVHHQNEGSITCVLFNQYGTVKTTSMLKVK 4034



 Score = 40.4 bits (93), Expect = 0.010
 Identities = 73/318 (22%), Positives = 115/318 (36%), Gaps = 33/318 (10%)

Query: 838  KEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQ-GKPRPELTWKKDGAEIDKNQINIRN 896
            K  +E   +RI    K+    +V E    V+ F+  +   +  W KDG EI+        
Sbjct: 3139 KLFVEGRDVRIRSIKKEV---QVIEKQRAVVEFEVNEDDVDAHWYKDGIEINFQVQERHK 3195

Query: 897  SETDTII---FIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGE 953
               +  I   FI +  +S +G+Y      ++   T       ++ P PPQ+++      E
Sbjct: 3196 YVVERRIHRMFISETRQSDAGEYTFVAGRNRSSVTL-----YVNAPEPPQVLQ------E 3244

Query: 954  NVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEY---YF 1010
               +T    K     A+    I    +  + W+   E    T      L  G EY     
Sbjct: 3245 LQPVTVQSGKPARFCAV----ISGRPQPKISWYKE-EQLLSTGFKCKFLHDGQEYTLLLI 3299

Query: 1011 RVFSENM----CGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAI 1066
              F E+     C    D  +   SA ++ +     +P  E   +   P    PL +T   
Sbjct: 3300 EAFPEDAAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQEMPVYP--PAIITPLQDTVTS 3357

Query: 1067 AGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCC 1126
             G  A   C V G    K++W      I     +RM   +    LEI +  P D GTY  
Sbjct: 3358 EGQPARFQCRVSGTDL-KVSWYSKDKKIKPSRFFRMTQFEDTYQLEIAEAYPEDEGTYTF 3416

Query: 1127 KAVNDLGTVEIECKLEVK 1144
             A N +G V     L ++
Sbjct: 3417 VASNAVGQVSSTANLSLE 3434



 Score = 40.0 bits (92), Expect = 0.013
 Identities = 44/211 (20%), Positives = 95/211 (45%), Gaps = 28/211 (13%)

Query: 270  RREEKKSAAFAKILDPAYQVD-------KGGRVRFVVELAD-PKLEVKWYKNGQEIRP-- 319
            R EE   +   ++  P + +        +G   RF +++   P  E  W+ +GQ+I    
Sbjct: 1442 RLEETDESQLERLYKPVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDY 1501

Query: 320  STKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTELFV--------REPPIMVTK 371
            + K + +  G Q ++ +     +D  E+ V A +    + + V         +   M  +
Sbjct: 1502 THKVVIKEDGTQSLIIVP-ATPSDSGEWTVVAQNRAGRSSISVILTVEAVEHQVKPMFVE 1560

Query: 372  QLEDTTAYCGERVELECEVSED-DANVKWFKNGEEIIPGPKSRY-RIRVEGKK--HILII 427
            +L++     G R+E++   + + + ++ W KN + I+P    +Y +IR+EG K    L I
Sbjct: 1561 KLKNVNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVP---HKYPKIRIEGTKGEAALKI 1617

Query: 428  EGATKADAAEY--SVMTTGGQSSAKLSVDLK 456
            +     D+A Y  + +   G+ + +  V+++
Sbjct: 1618 DSTVSQDSAWYTATAINKAGRDTTRCKVNVE 1648



 Score = 39.3 bits (90), Expect = 0.022
 Identities = 58/327 (17%), Positives = 107/327 (32%), Gaps = 45/327 (13%)

Query: 861  GEAVNLVIPFQGKPRPELTWKKDGAEIDKN---QINIRNSETDTIIFIRKAERSHSGKYD 917
            G+     +   G+P PE  W  DG +I  +   ++ I+   T ++I +  A  S SG++ 
Sbjct: 1471 GQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLIIV-PATPSDSGEWT 1529

Query: 918  L--QVKVDKFVETASIDIQIIDRPGPPQIV----------------KIEDVWGENVALTW 959
            +  Q +  +   +  + ++ ++    P  V                K+      N  + W
Sbjct: 1530 VVAQNRAGRSSISVILTVEAVEHQVKPMFVEKLKNVNIKEGSRLEMKVRATGNPNPDIVW 1589

Query: 960  TPPKD------------DGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNE 1007
                D            +G        I     +   W+T     ++     T   +  E
Sbjct: 1590 LKNSDIIVPHKYPKIRIEGTKGEAALKIDSTVSQDSAWYTATA-INKAGRDTTRCKVNVE 1648

Query: 1008 YYFR--------VFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQP 1059
              F         +         E A    E   +    + ++     D +  + P F + 
Sbjct: 1649 VEFAEPEPERKLIIPRGTYRAKEIAAPELEPLHLRYGQEQWEEGDLYDKEKQQKPFFKKK 1708

Query: 1060 LVNTYAIAGYNATLNCSVR--GNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPS 1117
            L +        A   C +   G+P   + W+ +   +    R RM +  G C+L+     
Sbjct: 1709 LTSLRLKRFGPAHFECRLTPIGDPTMVVEWLHDGKPLEAANRLRMINEFGYCSLDYGVAY 1768

Query: 1118 PYDGGTYCCKAVNDLGTVEIECKLEVK 1144
              D G   C+A N  GT      L VK
Sbjct: 1769 SRDSGIITCRATNKYGTDHTSATLIVK 1795



 Score = 38.9 bits (89), Expect = 0.028
 Identities = 44/162 (27%), Positives = 69/162 (42%), Gaps = 13/162 (8%)

Query: 304 PKLEVKWYKNGQEIRPST--KYIFEHKGCQRILFINNCQMTDDSEYYVTA----GDEKCS 357
           P  EV W+++GQ I  ST           +  L I      +   Y + A    G    +
Sbjct: 33  PVPEVSWFRDGQVISTSTLPGVQISFSDGRAKLTIPAVTKANSGRYSLKATNGSGQATST 92

Query: 358 TELFVR---EPPIMVTKQLEDTTAYCGERVELECEVSE-DDANVKWFKNGEEIIPGPKSR 413
            EL V+    PP  V ++L+  T   G +V L+  V+      VK++++G EI       
Sbjct: 93  AELLVKAETAPPNFV-QRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEI--QSSLD 149

Query: 414 YRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDL 455
           ++I  EG  + L+I  A   D+  YSV  T     A  + +L
Sbjct: 150 FQISQEGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAEL 191



 Score = 37.4 bits (85), Expect = 0.083
 Identities = 22/78 (28%), Positives = 39/78 (50%), Gaps = 7/78 (8%)

Query: 842  EPPKI--RIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQ-INIRNSE 898
            EPPK+   +P+H +     R G+++ L     G+P+P +TW ++G  + +NQ        
Sbjct: 4156 EPPKMLQEMPKHARC----REGDSIILECLISGEPQPVVTWFQNGVLLKQNQKFQFEEVN 4211

Query: 899  TDTIIFIRKAERSHSGKY 916
                ++I+      SGKY
Sbjct: 4212 CSHQLYIKDVNSQDSGKY 4229



 Score = 37.0 bits (84), Expect = 0.11
 Identities = 25/94 (26%), Positives = 40/94 (42%), Gaps = 1/94 (1%)

Query: 1054 PMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYR-MFSNQGVCTLE 1112
            P+F    V+   + G  A  +  V G P P+  W  +   IV+D  ++ +    G  +L 
Sbjct: 1457 PVFVLKPVSFKCLEGQTARFDLKVVGRPMPETFWFHDGQQIVNDYTHKVVIKEDGTQSLI 1516

Query: 1113 IRKPSPYDGGTYCCKAVNDLGTVEIECKLEVKVI 1146
            I   +P D G +   A N  G   I   L V+ +
Sbjct: 1517 IVPATPSDSGEWTVVAQNRAGRSSISVILTVEAV 1550



 Score = 35.8 bits (81), Expect = 0.24
 Identities = 25/91 (27%), Positives = 42/91 (46%), Gaps = 1/91 (1%)

Query: 559 TVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDS-STLVIDIAERD 617
           +V V+ G+    E  ISG P P+  W R  + I   +      S+ D  + L I    + 
Sbjct: 14  SVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKLTIPAVTKA 73

Query: 618 DSGVYHINLKNEAGEAHASIKVKVVDFPDPP 648
           +SG Y +   N +G+A ++ ++ V     PP
Sbjct: 74  NSGRYSLKATNGSGQATSTAELLVKAETAPP 104



 Score = 35.0 bits (79), Expect = 0.41
 Identities = 23/91 (25%), Positives = 37/91 (40%)

Query: 1054 PMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEI 1113
            P F Q L +     G    L   V G P P + + ++   I     +++     + +L I
Sbjct: 104  PNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLDFQISQEGDLYSLLI 163

Query: 1114 RKPSPYDGGTYCCKAVNDLGTVEIECKLEVK 1144
             +  P D GTY   A N +G      +L V+
Sbjct: 164  AEAYPEDSGTYSVNATNSVGRATSTAELLVQ 194



 Score = 35.0 bits (79), Expect = 0.41
 Identities = 15/57 (26%), Positives = 28/57 (49%)

Query: 303  DPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTE 359
            +P+  V W++NG  ++ + K+ FE   C   L+I +    D  +Y   A +   + E
Sbjct: 4185 EPQPVVTWFQNGVLLKQNQKFQFEEVNCSHQLYIKDVNSQDSGKYKCVAENNSGAVE 4241



 Score = 34.7 bits (78), Expect = 0.53
 Identities = 24/85 (28%), Positives = 41/85 (48%), Gaps = 3/85 (3%)

Query: 572  IPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAG 631
            + + G P P   W R +K+++E   RI+ E   +  +L I   ++ + G Y  +  N  G
Sbjct: 5204 VEVEGLPVPGVKWYR-NKSLLEPDERIKMERVGNVCSLEISNIQKGEGGEYMCHAVNIIG 5262

Query: 632  EAHASIKVKVVDFPDPPVA--PTVT 654
            EA +   V ++   +  VA  P VT
Sbjct: 5263 EAKSFANVDIMPQEERVVALPPPVT 5287



 Score = 33.9 bits (76), Expect = 0.91
 Identities = 27/119 (22%), Positives = 51/119 (42%), Gaps = 11/119 (9%)

Query: 418  VEGKKHILIIEGATKADAAEYSVM-------TTGGQSSAKLSVDLKPLKILTPLTDQTVN 470
            VE KK + +    T      + V+       T   +  A + + + P  +++ L + TV 
Sbjct: 896  VEVKKEVGVSITGTTVREERFEVLHGREAKVTETARVPAPVEIPVTPPTLVSGLKNVTVI 955

Query: 471  LGKEICLKCEISENIPGK---WTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDY 526
             G+ + L+C IS   P     W +    ++ S   ++  +  I +L+I  A  ED G +
Sbjct: 956  EGESVTLECHIS-GYPSPTVTWYREDYQIESSIDFQITFQSGIARLMIREAFAEDSGRF 1013



 Score = 33.5 bits (75), Expect = 1.2
 Identities = 35/140 (25%), Positives = 63/140 (45%), Gaps = 11/140 (7%)

Query: 799 KTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIR 858
           + K TI  +         +KA N +G +     +  +LVK    PP     + L+   +R
Sbjct: 62  RAKLTIPAVTKANSGRYSLKATNGSGQATS---TAELLVKAETAPPNF--VQRLQSMTVR 116

Query: 859 RVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTI--IFIRKAERSHSGKY 916
           + G  V L +   G P P + + +DGAEI ++ ++ + S+   +  + I +A    SG Y
Sbjct: 117 Q-GSQVRLQVRVTGIPTPVVKFYRDGAEI-QSSLDFQISQEGDLYSLLIAEAYPEDSGTY 174

Query: 917 DLQV--KVDKFVETASIDIQ 934
            +     V +   TA + +Q
Sbjct: 175 SVNATNSVGRATSTAELLVQ 194



 Score = 33.1 bits (74), Expect = 1.6
 Identities = 21/96 (21%), Positives = 41/96 (42%), Gaps = 3/96 (3%)

Query: 854 QTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQ---INIRNSETDTIIFIRKAER 910
           Q+ +   G          G P PE++W +DG  I  +    + I  S+    + I    +
Sbjct: 13  QSVVVLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKLTIPAVTK 72

Query: 911 SHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVK 946
           ++SG+Y L+        T++ ++ +     PP  V+
Sbjct: 73  ANSGRYSLKATNGSGQATSTAELLVKAETAPPNFVQ 108



 Score = 33.1 bits (74), Expect = 1.6
 Identities = 19/61 (31%), Positives = 27/61 (44%), Gaps = 1/61 (1%)

Query: 1071 ATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVN 1130
            AT  C     P  K+ W K+ + + +  +YRM S++ V  L I      D   Y C  V 
Sbjct: 2192 ATFECET-SEPFVKVKWYKDGMEVHEGDKYRMHSDRKVHFLSILTIDTSDAEDYSCVLVE 2250

Query: 1131 D 1131
            D
Sbjct: 2251 D 2251



 Score = 33.1 bits (74), Expect = 1.6
 Identities = 17/55 (30%), Positives = 28/55 (50%), Gaps = 1/55 (1%)

Query: 861  GEAVNLVIPFQGKPRPELTWKKDGAEIDKNQ-INIRNSETDTIIFIRKAERSHSG 914
            G++ N V  FQG P+P +TW  +   I +NQ   I + E  +I+ +      + G
Sbjct: 3958 GDSCNFVCHFQGYPQPIVTWYNNDMPIPRNQNFIIHSLENYSILTLSSVHHQNEG 4012



 Score = 33.1 bits (74), Expect = 1.6
 Identities = 24/94 (25%), Positives = 44/94 (46%), Gaps = 3/94 (3%)

Query: 565  GNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHI 624
            G+ + LE  ISGEP P   W + +  +++ + + + E    S  L I      DSG Y  
Sbjct: 4173 GDSIILECLISGEPQPVVTWFQ-NGVLLKQNQKFQFEEVNCSHQLYIKDVNSQDSGKYKC 4231

Query: 625  NLKNEAG--EAHASIKVKVVDFPDPPVAPTVTEV 656
              +N +G  E+ + + V+ V + +      + E+
Sbjct: 4232 VAENNSGAVESVSDLTVEPVTYRENSQFENIGEI 4265



 Score = 32.7 bits (73), Expect = 2.0
 Identities = 23/89 (25%), Positives = 37/89 (41%), Gaps = 7/89 (7%)

Query: 831  YSQPILVKEIIEPPKIRIPRHLK--QTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEID 888
            Y+      +++E P    PR +K        +G A       +G PRP + W KDG  + 
Sbjct: 5500 YTDSFFEFQVVEGP----PRFIKGISDCYAPIGTAAYFQCLVRGSPRPTVYWYKDGKLVQ 5555

Query: 889  KNQINIRNSETD-TIIFIRKAERSHSGKY 916
              +  +  S T    +FI    +S  G+Y
Sbjct: 5556 GRRFTVEESGTGFHNLFITSLVKSDEGEY 5584



 Score = 31.6 bits (70), Expect = 4.5
 Identities = 26/88 (29%), Positives = 33/88 (37%), Gaps = 4/88 (4%)

Query: 1059 PLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSP 1118
            PL +   I G  A L C V       + W  N   I  D R +         L I +   
Sbjct: 2450 PLKDVNVIEGTKAVLECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVKGTKQRLVINRTHA 2509

Query: 1119 YDGGTYCCKAVNDLGTVEIECKLEVKVI 1146
             D G Y  K +  +G VE  C L V+ I
Sbjct: 2510 SDEGPY--KLI--VGRVETNCNLSVEKI 2533


>gi|156104903 myomesin 2 [Homo sapiens]
          Length = 1465

 Score =  137 bits (345), Expect = 6e-32
 Identities = 218/984 (22%), Positives = 360/984 (36%), Gaps = 181/984 (18%)

Query: 255  GITDLRGMLKRLKRMRREEKKSAAFAKILDPAYQVDKGGRVRFVVELADPKLEVKWYKNG 314
            G T  R   KR+     EE+++ +  + L  AY   K  R RF+ ELA  + +V   ++ 
Sbjct: 64   GGTICRVCAKRVSTQEDEEQENRSRYQSLVAAYGEAK--RQRFLSELAHLEEDVHLARS- 120

Query: 315  QEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTELFVREPPIMVTKQLE 374
            Q      KY  +             QM +D      A +     E   R P I+V  +L 
Sbjct: 121  QARDKLDKYAIQ-------------QMMEDK----LAWERHTFEERISRAPEILV--RLR 161

Query: 375  DTTAYCGERVELECEVSEDDANV-KWFKNGEEIIPGPK-SRYRIRVEGKKHILIIEGATK 432
              T +    V+L   V      V +W+K+G  I    +  +YRI      H L I  A  
Sbjct: 162  SHTVWERMSVKLCFTVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVHTLEINRADF 221

Query: 433  ADAAEYSVMTTG--GQSSAKLSVDLK------------------PLKILTPLTDQTVNL- 471
             D A YS + T   GQ S   +V ++                  PL  + P T   V   
Sbjct: 222  DDTATYSAVATNAHGQVSTNAAVVVRRFRGDEEPFRSVGLPIGLPLSSMIPYTHFDVQFL 281

Query: 472  ----------GKEICLKC------EISENIP-GKWTKNGLPVQESDRLKVVHKGRIHKLV 514
                      G+ + LKC      ++    P  +W ++ + ++ES   K+        L 
Sbjct: 282  EKFGVTFRREGETVTLKCTMLVTPDLKRVQPRAEWYRDDVLLKESKWTKMFFGEGQASLS 341

Query: 515  IANALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPI 574
             ++   +DEG        Y + + ++  V D    +    DAD  VT   G  + L+   
Sbjct: 342  FSHLHKDDEG-------LYTLRIVSRGGVSDHSAFLFVR-DADPLVTGAPGAPMDLQCHD 393

Query: 575  SGEP-------PPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSG------- 620
            +          PP                 + T ++   +   + I +   +G       
Sbjct: 394  ANRDYVIVTWKPPNTTTESPVMGYFVDRCEVGTNNWVQCNDAPVKICKYPVTGLFEGRSY 453

Query: 621  VYHINLKNEAG---------------------------EAHASIKVKVVDF------PDP 647
            ++ +   N AG                           E    I +   D       P P
Sbjct: 454  IFRVRAVNSAGISRPSRVSDAVAALDPLDLRRLQAVHLEGEKEIAIYQDDLEGDAQVPGP 513

Query: 648  PVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLC-KETTFEP 706
            P     +E+  ++ +++WEPP   G  P++ YFIE+    S  W R+N     +   +  
Sbjct: 514  PTGVHASEISRNYVVLSWEPPTPRGKDPLM-YFIEKSVVGSGSWQRVNAQTAVRSPRYAV 572

Query: 707  KKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVT---SPPTLLTVDSVTDTTVTMRW 763
              ++EG +Y  R+ + N  G+S+PS  + P     VT   S P  +     T T+V ++W
Sbjct: 573  FDLMEGKSYVFRVLSANRHGLSEPSEITSPIQAQDVTVVPSAPGRVLASRNTKTSVVVQW 632

Query: 764  RPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAA 823
              P H     L GY ++ C  GT  W   N   I   +F + GL T  +   RVKAVNA 
Sbjct: 633  DRPKH--EEDLLGYYVDCCVAGTNLWEPCNHKPIGYNRFVVHGLTTGEQYIFRVKAVNAV 690

Query: 824  GASEPKYYSQPILVKEIIEPPKIRIPRH-LKQTYIRRVGEAVNL--VIPFQGKPRPELTW 880
            G SE    S  I V+       + +P H    T +   G ++ L   +P      P L +
Sbjct: 691  GMSENSQESDVIKVQ-----AALTVPSHPYGITLLNCDGHSMTLGWKVPKFSGGSPILGY 745

Query: 881  KKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFV---------ETASI 931
              D  E+     +  NS       +     +    Y+ ++               E    
Sbjct: 746  YLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPSEHFKC 805

Query: 932  DIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEH 991
            +   +  PGP   +   +V   ++ + W  P   G++ ++GY +   ++ + EW TV + 
Sbjct: 806  EAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEWITVNQ- 864

Query: 992  YHRTSAT----ITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGK-------IY 1040
               T+A     +++L  G  Y FRV + N  G+ + +  ++   V AR G          
Sbjct: 865  --TTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTSEPVLVEARPGTKEISAGVDE 922

Query: 1041 KNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRY 1100
            +  +Y  FD  E    +Q                           TW K+   I DD R+
Sbjct: 923  QGNIYLGFDCQEMTDASQ--------------------------FTWCKSYEEISDDERF 956

Query: 1101 RMFSNQGVCTLEIRKPSPYDGGTY 1124
            ++ +      L ++ P   D GTY
Sbjct: 957  KIETVGDHSKLYLKNPDKEDLGTY 980



 Score =  119 bits (298), Expect = 2e-26
 Identities = 129/547 (23%), Positives = 217/547 (39%), Gaps = 54/547 (9%)

Query: 621  VYHINLKNEAGEAHAS-----IKVKV-VDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGS 674
            ++ +   N  G +  S     IKV+  +  P  P   T+         + W+ P + GGS
Sbjct: 681  IFRVKAVNAVGMSENSQESDVIKVQAALTVPSHPYGITLLNCDGHSMTLGWKVPKFSGGS 740

Query: 675  PILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPS 734
            PILGY++++++     W  +N    K T      + EG  YE +I AVN  GI +PS PS
Sbjct: 741  PILGYYLDKREVHHKNWHEVNSSPSKPTILTVDGLTEGSLYEFKIAAVNLAGIGEPSDPS 800

Query: 735  RPFVPLAVTSP---PTL-LTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWI 790
              F   A T P   P   LT   V DT++ M W+ P + G++ + GY +++  E   +WI
Sbjct: 801  EHFKCEAWTMPEPGPAYDLTFCEVRDTSLVMLWKAPVYSGSSPVSGYFVDFREEDAGEWI 860

Query: 791  VANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPR 850
              N+         ++ L        RV+AVNA G  +P   S+P+LV+           R
Sbjct: 861  TVNQTTTANRYLKVSDLQQGKTYVFRVRAVNANGVGKPSDTSEPVLVE----------AR 910

Query: 851  HLKQTYIRRVGEAVNLVIPF---QGKPRPELTWKKDGAEI-DKNQINIRNSETDTIIFIR 906
               +     V E  N+ + F   +     + TW K   EI D  +  I      + ++++
Sbjct: 911  PGTKEISAGVDEQGNIYLGFDCQEMTDASQFTWCKSYEEISDDERFKIETVGDHSKLYLK 970

Query: 907  KAERSHSGKYDLQVK-VDKFVETASIDIQIIDR--------PGPPQIVKIE---DVWGEN 954
              ++   G Y + V   D    +  +D + ++R          P   +K E   +++ + 
Sbjct: 971  NPDKEDLGTYSVSVSDTDGVSSSFVLDPEELERLMALSNEIKNPTIPLKSELAYEIFDKG 1030

Query: 955  VALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSAT-ITELVIGNEYYFRVF 1013
                W   +     A   + I   +    E    I       AT I E+V+     F + 
Sbjct: 1031 RVRFWLQAEHLSPDASYRFIINDREVSDSE----IHRIKCDKATGIIEMVMDR---FSIE 1083

Query: 1014 SENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATL 1073
            +E    +       K  + +   G  +K  V E+ +F       +   +      ++ T 
Sbjct: 1084 NEGTYTVQIHDGKAKSQSSLVLIGDAFKT-VLEEAEFQRKEFLRKQGPHFAEYLHWDVTE 1142

Query: 1074 NCSVR-----GNPKPK--ITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCC 1126
             C VR      N K +    W+K+ V    +    +   +G+C L I K S  D G Y  
Sbjct: 1143 ECEVRLVCKVANTKKETVFKWLKDDVLYETETLPNL--ERGICELLIPKLSKKDHGEYKA 1200

Query: 1127 KAVNDLG 1133
               +D G
Sbjct: 1201 TLKDDRG 1207



 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 92/464 (19%), Positives = 162/464 (34%), Gaps = 92/464 (19%)

Query: 263  LKRLKRMRREEKKSAAFAKILDPAYQVDKGGRVRFVV--ELADPKLEVKWYKNGQEIRPS 320
            L+RL  +  E K      K  + AY++   GRVRF +  E   P    ++  N +E+  S
Sbjct: 1001 LERLMALSNEIKNPTIPLKS-ELAYEIFDKGRVRFWLQAEHLSPDASYRFIINDREVSDS 1059

Query: 321  TKYIFEHKGCQRIL--FINNCQMTDDSEYYVTAGDEKCSTEL------------------ 360
              +  +      I+   ++   + ++  Y V   D K  ++                   
Sbjct: 1060 EIHRIKCDKATGIIEMVMDRFSIENEGTYTVQIHDGKAKSQSSLVLIGDAFKTVLEEAEF 1119

Query: 361  ----FVREPPIMVTKQLE-DTTAYCGERVELECEVSEDDANVKWFKNG----EEIIPGPK 411
                F+R+      + L  D T  C  R+  +   ++ +   KW K+      E +P   
Sbjct: 1120 QRKEFLRKQGPHFAEYLHWDVTEECEVRLVCKVANTKKETVFKWLKDDVLYETETLPN-- 1177

Query: 412  SRYRIRVEGKKHILIIEGATKADAAEY------------SVMTTGGQ--------SSAKL 451
                  +E     L+I   +K D  EY            S++   G+         S   
Sbjct: 1178 ------LERGICELLIPKLSKKDHGEYKATLKDDRGQDVSILEIAGKVYDDMILAMSRVC 1231

Query: 452  SVDLKPLKILTPLTDQTVNLGKEICLKCEISENIPGKWTKNGLPVQESDRLKVVHKGRIH 511
                 PLK+L   T + + L    C     ++ +   W      +  S+ +++     + 
Sbjct: 1232 GKSASPLKVLC--TPEGIRLQ---CFMKYFTDEMKVNWCHKDAKISSSEHMRIGGSEEMA 1286

Query: 512  KLVIANALTEDEGDYVF----APDAYNVTLPAKVHVIDPPKIILDGLDA----------- 556
             L I     +D+G Y F      D +  +L       D          A           
Sbjct: 1287 WLQICEPTEKDKGKYTFEIFDGKDNHQRSLDLSGQAFDEAFAEFQQFKAAAFAEKNRGRL 1346

Query: 557  ----DNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIM---EGSGRIRTESYPDSSTL 609
                 + VT++ G  L L   + G P P+ +W + D+ I      S ++    Y    ++
Sbjct: 1347 IGGLPDVVTIMEGKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKY---VSM 1403

Query: 610  VIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPD--PPVAP 651
             I     +DSG Y IN+KN+ G     + V V    +  P +AP
Sbjct: 1404 TIKGVTSEDSGKYSINIKNKYGGEKIDVTVSVYKHGEKIPDMAP 1447



 Score = 40.0 bits (92), Expect = 0.013
 Identities = 25/72 (34%), Positives = 35/72 (48%), Gaps = 3/72 (4%)

Query: 1076 SVRGNPKPKITWMKNKVAI---VDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDL 1132
            +V+G P P + W K+   I    +  +YR+ SN GV TLEI +    D  TY   A N  
Sbjct: 176  TVQGFPTPVVQWYKDGSLICQAAEPGKYRIESNYGVHTLEINRADFDDTATYSAVATNAH 235

Query: 1133 GTVEIECKLEVK 1144
            G V     + V+
Sbjct: 236  GQVSTNAAVVVR 247



 Score = 35.4 bits (80), Expect = 0.31
 Identities = 21/77 (27%), Positives = 33/77 (42%), Gaps = 1/77 (1%)

Query: 1068 GYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQG-VCTLEIRKPSPYDGGTYCC 1126
            G    L C+V GNP P++ W KN   I     + +   Q    ++ I+  +  D G Y  
Sbjct: 1359 GKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDSGKYSI 1418

Query: 1127 KAVNDLGTVEIECKLEV 1143
               N  G  +I+  + V
Sbjct: 1419 NIKNKYGGEKIDVTVSV 1435



 Score = 31.2 bits (69), Expect = 5.9
 Identities = 22/94 (23%), Positives = 41/94 (43%), Gaps = 8/94 (8%)

Query: 861  GEAVNLVIPFQGKPRPELTWKKDGAEIDKNQ-INIRNSETDTI-IFIRKAERSHSGKYDL 918
            G+ +NL     G P PE+ W K+  +I  ++  +++  +   + + I+      SGKY +
Sbjct: 1359 GKTLNLTCTVFGNPDPEVIWFKNDQDIQLSEHFSVKVEQAKYVSMTIKGVTSEDSGKYSI 1418

Query: 919  QVKVDKFVETASIDIQI------IDRPGPPQIVK 946
             +K     E   + + +      I    PPQ  K
Sbjct: 1419 NIKNKYGGEKIDVTVSVYKHGEKIPDMAPPQQAK 1452


>gi|140560917 myomesin 1 isoform b [Homo sapiens]
          Length = 1589

 Score =  132 bits (332), Expect = 2e-30
 Identities = 206/909 (22%), Positives = 327/909 (35%), Gaps = 170/909 (18%)

Query: 304  PKLEVKWYKNGQEIRPST---KYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTEL 360
            P+  V WYKN   I       KYI E +     L IN C   D ++Y  +A + K     
Sbjct: 304  PEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGCDFEDTAQYRASAMNVKGELSA 363

Query: 361  FVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEG 420
            +      +V K+      Y GE  E              F  G   +P            
Sbjct: 364  YAS----VVVKR------YKGEFDETR------------FHAGASTMP------------ 389

Query: 421  KKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCE 480
                             + V   G  S  ++  D K   +      +T++LG  + +  E
Sbjct: 390  ---------------LSFGVTPYGYASRFEIHFDDK-FDVSFGREGETMSLGCRVVITPE 433

Query: 481  ISENIPG-KWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDE---------GDYVFAP 530
            I    P  +W +NG+P+  S  ++ +  G    L  ++   EDE         G+Y    
Sbjct: 434  IKHFQPEIQWYRNGVPLSPSKWVQTLWSGERATLTFSHLNKEDEGLYTIRVRMGEYYEQY 493

Query: 531  DAYNVTLPAKVHVIDPPKIILD--GLDADNTVTVIAGNKLRLE--IPISGEPPPKA---- 582
             AY     A   +   P   LD   L+A+    +I+  +  ++   PI G    K     
Sbjct: 494  SAYVFVRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGT 553

Query: 583  -MWSRGD-----------KAIMEGSG---RIRT--------ESYPDSSTLVIDIAERDDS 619
              WS+ +             ++EG     R+R          S        +D AE+   
Sbjct: 554  DSWSQCNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEK--- 610

Query: 620  GVYHINLKNEAGEAHASIKVKVVDFPD------PPVAPTVTEVGDDWCIMNWEPPAYDGG 673
                  LK+          +   + P       PP   +VTE    + +++W+PP   G 
Sbjct: 611  ----ARLKSRPSAPWTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGH 666

Query: 674  SPILGYFIERKKKQSSRWMRLNFDL-CKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSM 732
              I+ YF+E+ +  +  W R+N +L  K   F    + EG +Y  R+   N+ G+ +PS 
Sbjct: 667  EGIM-YFVEKCEAGTENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSE 725

Query: 733  PSRPFV---PLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDW 789
             +   V    L +   P  +     TDT+V + W   +   A  L GY +E    G+  W
Sbjct: 726  ATEVTVVGDKLDIPKAPGKIIPSRNTDTSVVVSWE--ESKDAKELVGYYIEASVAGSGKW 783

Query: 790  IVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIP 849
               N + +  ++FT  GL T      RV+AVNAAG SE    S+ I VK  I PP     
Sbjct: 784  EPCNNNPVKGSRFTCHGLVTGQSYIFRVRAVNAAGLSEYSQDSEAIEVKAAIAPPS---- 839

Query: 850  RHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRN---------SETD 900
                 T +    +++ L     G  +P+   K  GAEI    +N R           E +
Sbjct: 840  PPCDITCLESFRDSMVL-----GWKQPD---KIGGAEITGYYVNYREVIDGVPGKWREAN 891

Query: 901  TIIFIRKAERSHSGK----YDLQVKVDKFV---------ETASIDIQIIDRPGPPQIVKI 947
                  +A +  + K    Y  QV               E    +   I  PGPP  +K 
Sbjct: 892  VKAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSECFKCEEWTIAVPGPPHSLKC 951

Query: 948  EDVWGENVALTWTPPKDDGNAAITGY--TIQKADKKSMEWFTVIE-HYHRTSATITELVI 1004
             +V  +++ L W PP   G   +TGY   +++A  K  +W  + E         +  L  
Sbjct: 952  SEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEAAIKNVYLKVRGLKE 1011

Query: 1005 GNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTY 1064
            G  Y FRV + N  G+ + + +        R G                    + +VN  
Sbjct: 1012 GVSYVFRVRAINQAGVGKPSDLAGPVVAETRPGT------------------KEVVVNVD 1053

Query: 1065 AIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTY 1124
                 +    C  +  PK + +W K+ V+  D PR  + S      +  +     D G Y
Sbjct: 1054 DDGVISLNFECD-KMTPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIY 1112

Query: 1125 CCKAVNDLG 1133
             C   +  G
Sbjct: 1113 SCDVTDTDG 1121



 Score = 95.1 bits (235), Expect = 3e-19
 Identities = 127/568 (22%), Positives = 216/568 (38%), Gaps = 71/568 (12%)

Query: 619  SGVYHINLKNEAGEAHAS-----IKVKV-VDFPDPPVAPTVTEVGDDWCIMNWEPPAYDG 672
            S ++ +   N AG +  S     I+VK  +  P PP   T  E   D  ++ W+ P   G
Sbjct: 806  SYIFRVRAVNAAGLSEYSQDSEAIEVKAAIAPPSPPCDITCLESFRDSMVLGWKQPDKIG 865

Query: 673  GSPILGYFIERKKKQSS---RWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISK 729
            G+ I GY++  ++       +W   N     E  ++   + E + Y+ ++ A+N  G+  
Sbjct: 866  GAEITGYYVNYREVIDGVPGKWREANVKAVSEEAYKISNLKENMVYQFQVAAMNMAGLGA 925

Query: 730  PSMPSRPFV----PLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYV--LEYCF 783
            PS  S  F      +AV  PP  L    V   ++ ++W+PP H G   + GY   L+   
Sbjct: 926  PSAVSECFKCEEWTIAVPGPPHSLKCSEVRKDSLVLQWKPPVHSGRTPVTGYFVDLKEAK 985

Query: 784  EGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEP 843
               + W   N+  I      + GL        RV+A+N AG  +P   + P++ +     
Sbjct: 986  AKEDQWRGLNEAAIKNVYLKVRGLKEGVSYVFRVRAINQAGVGKPSDLAGPVVAE----- 1040

Query: 844  PKIRIPRHLKQTYIRRVGEAVNLVIPFQ---GKPRPELTWKKDGAEI-DKNQINIRNSET 899
                  R   +  +  V +   + + F+     P+ E +W KD     D  ++ + +   
Sbjct: 1041 -----TRPGTKEVVVNVDDDGVISLNFECDKMTPKSEFSWSKDYVSTEDSPRLEVESKGN 1095

Query: 900  DTIIFIRKAERSHSGKYDLQV-KVDKFVETASIDIQIIDR----------PGPP--QIVK 946
             T +  +       G Y   V   D    +  ID + + R          P  P    + 
Sbjct: 1096 KTKMTFKDLGMDDLGIYSCDVTDTDGIASSYLIDEEELKRLLALSHEHKFPTVPVKSELA 1155

Query: 947  IEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGN 1006
            +E +    V       K  GNA +  Y     +K+  E      H  R +  I       
Sbjct: 1156 VEILEKGQVRFWMQAEKLSGNAKV-NYIFN--EKEIFEGPKYKMHIDRNTGII------- 1205

Query: 1007 EYYFRVFSENMCGL----SEDATMTKESAVIARDGKIYKNPVYEDFDF-------SEAPM 1055
            E +     +   G      +D   T  S V+   G ++K  + ++ +F        + P 
Sbjct: 1206 EMFMEKLQDEDEGTYTFQLQDGKATNHSTVVL-VGDVFKK-LQKEAEFQRQEWIRKQGPH 1263

Query: 1056 FTQPLVNTYAIAG-YNATLNCSVRGNPK-PKITWMKNKVAIVDDPRYRMFSNQGVCTLEI 1113
            F + L  ++ + G  N  L C V    K   I W K++  I  D ++      G+CTL I
Sbjct: 1264 FVEYL--SWEVTGECNVLLKCKVANIKKETHIVWYKDEREISVDEKHDF--KDGICTLLI 1319

Query: 1114 RKPSPYDGGTYCCKAVNDLGTVEIECKL 1141
             + S  D G Y     +D G  +   KL
Sbjct: 1320 TEFSKKDAGIYEVILKDDRGKDKSRLKL 1347



 Score = 57.4 bits (137), Expect = 8e-08
 Identities = 101/453 (22%), Positives = 166/453 (36%), Gaps = 92/453 (20%)

Query: 263  LKRLKRMRREEKKSAAFAKILDPAYQVDKGGRVRFVV--ELADPKLEVKWYKNGQEIRPS 320
            LKRL  +  E K      K  + A ++ + G+VRF +  E      +V +  N +EI   
Sbjct: 1133 LKRLLALSHEHKFPTVPVKS-ELAVEILEKGQVRFWMQAEKLSGNAKVNYIFNEKEIFEG 1191

Query: 321  TKY---IFEHKGCQRILFINNCQMTDDSEYYVTAGDEKC---STELFVREPPIMVTKQLE 374
             KY   I  + G    +F+   Q  D+  Y     D K    ST + V +    + K+ E
Sbjct: 1192 PKYKMHIDRNTGIIE-MFMEKLQDEDEGTYTFQLQDGKATNHSTVVLVGDVFKKLQKEAE 1250

Query: 375  --------------------DTTAYCGERVELECEVS--EDDANVKWFKNGEEIIPGPKS 412
                                + T  C   V L+C+V+  + + ++ W+K+  EI    K 
Sbjct: 1251 FQRQEWIRKQGPHFVEYLSWEVTGECN--VLLKCKVANIKKETHIVWYKDEREISVDEKH 1308

Query: 413  RYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLG 472
             ++   +G   +LI E  +K DA  Y V+    +   K  + L        + +    L 
Sbjct: 1309 DFK---DGICTLLITE-FSKKDAGIYEVILKDDRGKDKSRLKL--------VDEAFKELM 1356

Query: 473  KEICLKCEIS-----------------------ENIPGKWTKNGLPVQESDRLKVVHKGR 509
             E+C K  +S                       E++   W+ NG  ++ SDR+K    G 
Sbjct: 1357 MEVCKKIALSATDLKIQSTAEGIQLYSFVTYYVEDLKVNWSHNGSAIRYSDRVKTGVTGE 1416

Query: 510  IHKLVIANALTEDEGDYVF----APDAYNVTLPAKVHVIDPPKI---------------- 549
               L I      D+G YV         +  T+       D                    
Sbjct: 1417 QIWLQINEPTPNDKGKYVMELFDGKTGHQKTVDLSGQAYDEAYAEFQRLKQAAIAEKNRA 1476

Query: 550  -ILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSST 608
             +L GL   + VT+  G  L L   + G+PPP+  W + +KA+              ++ 
Sbjct: 1477 RVLGGL--PDVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAY 1534

Query: 609  LVIDIAERDDSGVYHINLKNEAGEAHASIKVKV 641
              I+     DSG Y + +KN+ G   +   V V
Sbjct: 1535 FTINGVSTADSGKYGLVVKNKYGSETSDFTVSV 1567



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 27/78 (34%), Positives = 40/78 (51%), Gaps = 3/78 (3%)

Query: 1070 NATLNCSVRGNPKPKITWMKNKVAI---VDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCC 1126
            N  L+CS+ G P+P++TW KN+V I    +  +Y + S  G+ TLEI      D   Y  
Sbjct: 293  NVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGCDFEDTAQYRA 352

Query: 1127 KAVNDLGTVEIECKLEVK 1144
             A+N  G +     + VK
Sbjct: 353  SAMNVKGELSAYASVVVK 370



 Score = 40.8 bits (94), Expect = 0.007
 Identities = 35/139 (25%), Positives = 62/139 (44%), Gaps = 4/139 (2%)

Query: 818  KAVNAAGASEPKYYSQPILVKE--IIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPR 875
            K V+ +G +  + Y++   +K+  I E  + R+   L      + G+A+NL     G P 
Sbjct: 1446 KTVDLSGQAYDEAYAEFQRLKQAAIAEKNRARVLGGLPDVVTIQEGKALNLTCNVWGDPP 1505

Query: 876  PELTW-KKDGAEIDKNQINIRNSETDTIIF-IRKAERSHSGKYDLQVKVDKFVETASIDI 933
            PE++W K + A    +  N++     T  F I     + SGKY L VK     ET+   +
Sbjct: 1506 PEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTADSGKYGLVVKNKYGSETSDFTV 1565

Query: 934  QIIDRPGPPQIVKIEDVWG 952
             +       ++  +E + G
Sbjct: 1566 SVFIPEEEARMAALESLKG 1584



 Score = 36.2 bits (82), Expect = 0.18
 Identities = 38/147 (25%), Positives = 61/147 (41%), Gaps = 17/147 (11%)

Query: 498 ESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKIILDGLDAD 557
           E    KVV + +  +L +   L E E         Y+  L    H++  P+ I+      
Sbjct: 237 EKKSRKVVIREKAERLSLRKTLEETE--------TYHAKLNED-HLLHAPEFIIK----P 283

Query: 558 NTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAI--MEGSGRIRTESYPDSSTLVIDIAE 615
            + TV     ++L   I+G P P+  W +    I      G+   ES     TL I+  +
Sbjct: 284 RSHTVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGCD 343

Query: 616 RDDSGVYHINLKNEAGE--AHASIKVK 640
            +D+  Y  +  N  GE  A+AS+ VK
Sbjct: 344 FEDTAQYRASAMNVKGELSAYASVVVK 370



 Score = 36.2 bits (82), Expect = 0.18
 Identities = 20/68 (29%), Positives = 30/68 (44%), Gaps = 1/68 (1%)

Query: 1068 GYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRM-FSNQGVCTLEIRKPSPYDGGTYCC 1126
            G    L C+V G+P P+++W+KN+ A+  D    + F         I   S  D G Y  
Sbjct: 1491 GKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTADSGKYGL 1550

Query: 1127 KAVNDLGT 1134
               N  G+
Sbjct: 1551 VVKNKYGS 1558


>gi|58331253 obscurin, cytoskeletal calmodulin and titin-interacting
            RhoGEF isoform a [Homo sapiens]
          Length = 6620

 Score =  129 bits (323), Expect = 2e-29
 Identities = 100/370 (27%), Positives = 164/370 (44%), Gaps = 19/370 (5%)

Query: 275  KSAAFAKILDPAYQVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRIL 334
            K   F K LD     ++ G +    E++DP+  V W K+G ++ PS KY F H    R L
Sbjct: 2645 KPVVFLKALDDL-SAEERGTLALQCEVSDPEAHVVWRKDGVQLGPSDKYDFLHTAGTRGL 2703

Query: 335  FINNCQMTDDSEYYVTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDD 394
             +++    D   Y    G E+    + V +  + +TK+L+      GE    EC +S + 
Sbjct: 2704 VVHDVSPEDAGLYTCHVGSEETRARVRVHDLHVGITKRLKTMEVLEGESCSFECVLSHES 2763

Query: 395  AN--VKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLS 452
            A+    W   G+ +  G  SR++   +G+K+IL++  A  +DA E      G  S A L 
Sbjct: 2764 ASDPAMWTVGGKTV--GSSSRFQATRQGRKYILVVREAAPSDAGEVVFSVRGLTSKASLI 2821

Query: 453  VDLKPLKILTPLTDQTVNLGKEICLKCEISE-NIPGKWTKNGLPVQESDRLKVVHKGRIH 511
            V  +P  I+ PL DQ V  G+++ L+CE+S    P  W K+   +++S +  VV +G + 
Sbjct: 2822 VRERPAAIIKPLEDQWVAPGEDVELRCELSRAGTPVHWLKDRKAIRKSQKYDVVCEGTMA 2881

Query: 512  KLVIANALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKII---LDGLDADNTVTVIAGNKL 568
             LVI  A  +D G+Y    +A   T  A +HV +        L  L  +   T +   K 
Sbjct: 2882 MLVIRGASLKDAGEYTCEVEASKST--ASLHVEEKANCFTEELTNLQVEEKGTAVFTCK- 2938

Query: 569  RLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKN 628
                  +  P     W +G    +  SG+ +      +  L I   E+ DS  Y  ++  
Sbjct: 2939 ------TEHPAATVTWRKG-LLELRASGKHQPSQEGLTLRLTISALEKADSDTYTCDIGQ 2991

Query: 629  EAGEAHASIK 638
                A   ++
Sbjct: 2992 AQSRAQLLVQ 3001



 Score =  127 bits (318), Expect = 8e-29
 Identities = 99/387 (25%), Positives = 168/387 (43%), Gaps = 24/387 (6%)

Query: 268  RMRREEKKSAAFAK--ILDPAYQVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIF 325
            R+R  E K   FAK  +     Q + G       E+A  + EV WYK+G+++  S+K   
Sbjct: 880  RLRVSEPK-VVFAKEQLARRKLQAEAGASATLSCEVAQAQTEVTWYKDGKKLSSSSKVCM 938

Query: 326  EHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTELFVREPPIMVTKQL---EDTTAYCGE 382
            E  GC R L +      D  EY   AG ++ S  L V+EP ++  K      +  A  G 
Sbjct: 939  EATGCTRRLVVQQAGQADAGEYSCEAGGQRLSFHLDVKEPKVVFAKDQVAHSEVQAEAGA 998

Query: 383  RVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGK--KHILIIEGATKADAAEYSV 440
               L CEV++    V W+K+G+++     S  ++ VE K  +  L+++ A K DA +YS 
Sbjct: 999  SATLSCEVAQAQTEVMWYKDGKKL----SSSLKVHVEAKGCRRRLVVQQAGKTDAGDYSC 1054

Query: 441  MTTGGQSSAKLSVDLKPL---KILTPLTDQTVNLGKEICLKCEISE-NIPGKWTKNGLPV 496
               G + S +L +    +   K  +   +     G    L CE+++      W K+G  +
Sbjct: 1055 EARGQRVSFRLHITEPKMMFAKEQSVHNEVQAEAGASAMLSCEVAQAQTEVTWYKDGKKL 1114

Query: 497  QESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKIILDGLDA 556
              S ++ +  KG   +LV+  A   D G+Y        V+    +H+ +P  +       
Sbjct: 1115 SSSSKVGMEVKGCTRRLVLPQAGKADAGEYSCEAGGQRVSF--HLHITEPKGVFAKEQSV 1172

Query: 557  DNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAER 616
             N V   AG    L   ++ +P  +  W +  K  +  S ++R E    +  LV+    +
Sbjct: 1173 HNEVQAEAGTTAMLSCEVA-QPQTEVTWYKDGKK-LSSSSKVRMEVKGCTRRLVVQQVGK 1230

Query: 617  DDSGVYHINLKNEAGEAHASIKVKVVD 643
             D+G Y      EAG    S ++ + +
Sbjct: 1231 ADAGEYSC----EAGGQRVSFQLHITE 1253



 Score =  122 bits (306), Expect = 2e-27
 Identities = 100/403 (24%), Positives = 175/403 (43%), Gaps = 31/403 (7%)

Query: 248  EKIAFQYGITDLRGMLKRLKRMRREEKKSAAFAKILDPAYQVDKGGRVRFVVELADPKLE 307
            ++++F   IT+ +G+  + + +  E               Q + G       E+A P+ E
Sbjct: 1151 QRVSFHLHITEPKGVFAKEQSVHNE--------------VQAEAGTTAMLSCEVAQPQTE 1196

Query: 308  VKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTELFVREPPI 367
            V WYK+G+++  S+K   E KGC R L +      D  EY   AG ++ S +L + EP  
Sbjct: 1197 VTWYKDGKKLSSSSKVRMEVKGCTRRLVVQQVGKADAGEYSCEAGGQRVSFQLHITEPKA 1256

Query: 368  MVTKQL---EDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHI 424
            +  K+     +     G    L CEV++    V W+K+G+++     S+ RI   G    
Sbjct: 1257 VFAKEQLVHNEVRTEAGASATLSCEVAQAQTEVTWYKDGKKL--SSSSKVRIEAAGCMRQ 1314

Query: 425  LIIEGATKADAAEYSVMTTGGQSSAKLSV-DLKPLKILTPLTDQTV--NLGKEICLKCEI 481
            L+++ A +ADA EY+    G + S  L V + K +     L  + V    G    L CE+
Sbjct: 1315 LVVQQAGQADAGEYTCEAGGQRLSFHLDVSEPKAVFAKEQLAHRKVQAEAGAIATLSCEV 1374

Query: 482  SE-NIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAK 540
            ++      W K+G  +  S ++++   G   +LV+  A   D G+Y  + +A    L   
Sbjct: 1375 AQAQTEVTWYKDGKKLSSSSKVRMEAVGCTRRLVVQQACQADTGEY--SCEAGGQRLSFS 1432

Query: 541  VHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRT 600
            + V +P  +          V   AG    L   ++ +   + MW +  K  +  S ++R 
Sbjct: 1433 LDVAEPKVVFAKEQPVHREVQAQAGASTTLSCEVA-QAQTEVMWYKDGKK-LSFSSKVRM 1490

Query: 601  ESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVD 643
            E+   +  LV+  A +  +G Y      EAG    S  + V +
Sbjct: 1491 EAVGCTRRLVVQQAGQAVAGEYSC----EAGSQRLSFHLHVAE 1529



 Score =  121 bits (304), Expect = 3e-27
 Identities = 197/876 (22%), Positives = 330/876 (37%), Gaps = 104/876 (11%)

Query: 130  KAGKHLQLKETFERHSRVYTFEMQIIKAKDNFAGNYRCEVTYKDKFDSCSFDLEVHESTG 189
            K GK L         +   T  + + +A    AG Y CE   +      SF L+V E   
Sbjct: 925  KDGKKLSSSSKVCMEATGCTRRLVVQQAGQADAGEYSCEAGGQ----RLSFHLDVKE--- 977

Query: 190  TTPNIDIRSAFKRSGEGQEDAGELDFSGLLKRREVKQQEEEPQVDVWELLKN-------A 242
              P +          E Q +AG    S  L     + Q E       + L +       A
Sbjct: 978  --PKVVFAKDQVAHSEVQAEAGA---SATLSCEVAQAQTEVMWYKDGKKLSSSLKVHVEA 1032

Query: 243  KPSEYEKIAFQYGITDL-------RGMLKRLKRMRREEKKSAAFAKILDPAYQVDKGGRV 295
            K      +  Q G TD        RG     +    E K   A  + +    Q + G   
Sbjct: 1033 KGCRRRLVVQQAGKTDAGDYSCEARGQRVSFRLHITEPKMMFAKEQSVHNEVQAEAGASA 1092

Query: 296  RFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEK 355
                E+A  + EV WYK+G+++  S+K   E KGC R L +      D  EY   AG ++
Sbjct: 1093 MLSCEVAQAQTEVTWYKDGKKLSSSSKVGMEVKGCTRRLVLPQAGKADAGEYSCEAGGQR 1152

Query: 356  CSTELFVREPPIMVTKQL---EDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKS 412
             S  L + EP  +  K+     +  A  G    L CEV++    V W+K+G+++     S
Sbjct: 1153 VSFHLHITEPKGVFAKEQSVHNEVQAEAGTTAMLSCEVAQPQTEVTWYKDGKKL--SSSS 1210

Query: 413  RYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSV-DLKPLKILTPLTDQTV-- 469
            + R+ V+G    L+++   KADA EYS    G + S +L + + K +     L    V  
Sbjct: 1211 KVRMEVKGCTRRLVVQQVGKADAGEYSCEAGGQRVSFQLHITEPKAVFAKEQLVHNEVRT 1270

Query: 470  NLGKEICLKCEISE-NIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVF 528
              G    L CE+++      W K+G  +  S ++++   G + +LV+  A   D G+Y  
Sbjct: 1271 EAGASATLSCEVAQAQTEVTWYKDGKKLSSSSKVRIEAAGCMRQLVVQQAGQADAGEYTC 1330

Query: 529  APDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGD 588
              +A    L   + V +P  +      A   V   AG    L   ++        +  G 
Sbjct: 1331 --EAGGQRLSFHLDVSEPKAVFAKEQLAHRKVQAEAGAIATLSCEVAQAQTEVTWYKDGK 1388

Query: 589  KAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPP 648
            K  +  S ++R E+   +  LV+  A + D+G Y      EAG    S  + V +     
Sbjct: 1389 K--LSSSSKVRMEAVGCTRRLVVQQACQADTGEYSC----EAGGQRLSFSLDVAE----- 1437

Query: 649  VAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKK 708
              P V    +    ++ E  A  G S  L   + + + +   W +      K+ +F  K 
Sbjct: 1438 --PKVVFAKEQ--PVHREVQAQAGASTTLSCEVAQAQTE-VMWYKDG----KKLSFSSKV 1488

Query: 709  MIEGVAYEVRIFAVNA-----------IGISKPSMPSRPFVPLAV--TSPPTLLTVDSVT 755
             +E V    R+    A            G  + S       P AV     P    V +  
Sbjct: 1489 RMEAVGCTRRLVVQQAGQAVAGEYSCEAGSQRLSFHLHVAEPKAVFAKEQPASREVQAEA 1548

Query: 756  DTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTE-DWIVANKDLIDKTKFTITGLPTDAKIF 814
             T+ T+                  E     TE  W    K L   +K  +  +    ++ 
Sbjct: 1549 GTSATLS----------------CEVAQAQTEVTWYKDGKKLSSSSKVRMEAVGCTRRLV 1592

Query: 815  VRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRV----GEAVNLVIPF 870
            V+      AG    K   Q +     +  PK+   +  +Q   R V    G +  L    
Sbjct: 1593 VQEAGQADAGEYSCKAGDQRLSFHLHVAEPKVVFAK--EQPAHREVQAEAGASATLSCEV 1650

Query: 871  QGKPRPELTWKKDGAEI-DKNQINIRNSETDTIIFIRKAERSHSGKYDLQV---KVDKFV 926
              + + E+TW KDG ++   +++ +        + +++A ++ +G+Y  +    ++   +
Sbjct: 1651 -AQAQTEVTWYKDGKKLSSSSKVRVEAVGCTRRLVVQQAGQADAGEYSCEAGGQRLSFRL 1709

Query: 927  ETASIDIQIIDRP--GPPQIVKIEDVWGENVALTWT 960
              A ++ QI +RP    P +VK      E++ LT T
Sbjct: 1710 HVAELEPQISERPCRREPLVVKEH----EDIILTAT 1741



 Score =  108 bits (270), Expect = 3e-23
 Identities = 88/353 (24%), Positives = 153/353 (43%), Gaps = 14/353 (3%)

Query: 290  DKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYV 349
            ++GG   F   ++   + V W+++G  ++PS K+     G    L I++  + D  +  V
Sbjct: 1911 EEGGEATFQCVVSPSDVAVVWFRDGALLQPSEKFAISQSGASHSLTISDLVLEDAGQITV 1970

Query: 350  TAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPG 409
             A     S  L VRE P++  K+LE  T      V LE E++     ++W +N   + PG
Sbjct: 1971 EAEGASSSAALRVREAPVLFKKKLEPQTVEERSSVTLEVELTRPWPELRWTRNATALAPG 2030

Query: 410  PKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTV 469
                  I  EG +H L++     AD   +   T   ++ AKL+V+++ ++++  L     
Sbjct: 2031 --KNVEIHAEGARHRLVLHNVGFADRGFFGCETPDDKTQAKLTVEMRQVRLVRGLQAVEA 2088

Query: 470  NLGKEICLKCEISE-NIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVF 528
                   ++ ++S  ++ G WT++GL  Q+     +  +G +H L ++    ED G  VF
Sbjct: 2089 REQGTATMEVQLSHADVDGSWTRDGLRFQQGPTCHLAVRGPMHTLTLSGLRPEDSGLMVF 2148

Query: 529  APDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGD 588
               A  V   A++ V + P      L     V      K+ LE  +S  P     W + D
Sbjct: 2149 --KAEGVHTSARLVVTELPVSFSRPL---QDVVTTEKEKVTLECELS-RPNVDVRWLK-D 2201

Query: 589  KAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKV 641
               +     +   +     +L I   E  D GVY      +A +A +S  VKV
Sbjct: 2202 GVELRAGKTMAIAAQGACRSLTIYRCEFADQGVYVC----DAHDAQSSASVKV 2250



 Score =  107 bits (268), Expect = 5e-23
 Identities = 74/265 (27%), Positives = 120/265 (45%), Gaps = 10/265 (3%)

Query: 288  QVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEY 347
            Q + G       E+A  + EV WYK+G+++  S+K   E  GC R L +      D  EY
Sbjct: 1545 QAEAGTSATLSCEVAQAQTEVTWYKDGKKLSSSSKVRMEAVGCTRRLVVQEAGQADAGEY 1604

Query: 348  YVTAGDEKCSTELFVREPPIMVTKQL---EDTTAYCGERVELECEVSEDDANVKWFKNGE 404
               AGD++ S  L V EP ++  K+     +  A  G    L CEV++    V W+K+G+
Sbjct: 1605 SCKAGDQRLSFHLHVAEPKVVFAKEQPAHREVQAEAGASATLSCEVAQAQTEVTWYKDGK 1664

Query: 405  EIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSV-DLKPLKILTP 463
            ++     S+ R+   G    L+++ A +ADA EYS    G + S +L V +L+P     P
Sbjct: 1665 KL--SSSSKVRVEAVGCTRRLVVQQAGQADAGEYSCEAGGQRLSFRLHVAELEPQISERP 1722

Query: 464  LTDQ--TVNLGKEICLKCEISENIPG--KWTKNGLPVQESDRLKVVHKGRIHKLVIANAL 519
               +   V   ++I L   ++        W K+G+ ++ S R +   +G  H L +  A 
Sbjct: 1723 CRREPLVVKEHEDIILTATLATPSAATVTWLKDGVEIRRSKRHETASQGDTHTLTVHGAQ 1782

Query: 520  TEDEGDYVFAPDAYNVTLPAKVHVI 544
              D   Y     A     P +V  +
Sbjct: 1783 VLDSAIYSCRVGAEGQDFPVQVEEV 1807



 Score =  106 bits (265), Expect = 1e-22
 Identities = 88/339 (25%), Positives = 149/339 (43%), Gaps = 14/339 (4%)

Query: 308  VKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTELFVREPPI 367
            V+W+K  + +R   ++     G +  L I      D  EY    G E+ S  L VR  P 
Sbjct: 3655 VEWWKGHETLRDGDRHSLRQDGARCELQIRGLVAEDAGEYLCMCGKERTSAMLTVRAMPS 3714

Query: 368  MVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILII 427
               + L +  A  G+   L CE+S+  A V+W K  E +  G   R+ +R +G +  L I
Sbjct: 3715 KFIEGLRNEEATEGDTATLWCELSKA-APVEWRKGHETLRDG--DRHSLRQDGSRCELQI 3771

Query: 428  EGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCEISENIPG 487
             G    DA EYS +    ++SA L+V   P + +  + +Q    G    L+CE+S+  P 
Sbjct: 3772 RGLAVVDAGEYSCVCGQERTSATLTVRALPARFIEDVKNQEAREGATAVLQCELSKAAPV 3831

Query: 488  KWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDY--VFAPDAYNVTLPAKVHVID 545
            +W K    ++  DR  +   G   +L I      D G+Y  V   +  + TL  +     
Sbjct: 3832 EWRKGSETLRGGDRYSLRQDGTRCELQIHGLSVADTGEYSCVCGQERTSATLTVRA---- 3887

Query: 546  PPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPD 605
            P  +  + L    ++    G+   L+  +S EP    +WS+G    ++ +GR        
Sbjct: 3888 PQPVFREPL---QSLQAEEGSTATLQCELS-EPTATVVWSKGGLQ-LQANGRREPRLQGC 3942

Query: 606  SSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDF 644
            ++ LV+   +R+D+G Y     ++A  A  ++    V F
Sbjct: 3943 TAELVLQDLQREDTGEYTCTCGSQATSATLTVTAAPVRF 3981



 Score =  106 bits (264), Expect = 1e-22
 Identities = 78/287 (27%), Positives = 128/287 (44%), Gaps = 10/287 (3%)

Query: 308  VKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTELFVREPPI 367
            V+W K  + +R   +YI   +G +  L I    M D  EY    G E+ S  L +R  P 
Sbjct: 3479 VEWRKGPENLRDGDRYILRQEGTRCELQICGLAMADAGEYLCVCGQERTSATLTIRALPA 3538

Query: 368  MVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILII 427
               + +++  A  G    L+CE++   A V+W K  E +  G   RY +R +G K  L I
Sbjct: 3539 RFIEDVKNQEAREGATAVLQCELNSA-APVEWRKGSETLRDG--DRYSLRQDGTKCELQI 3595

Query: 428  EGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCEISENIPG 487
             G   AD  EYS +    ++SA L+V   P+K    L ++    G    L+CE+S+  P 
Sbjct: 3596 RGLAMADTGEYSCVCGQERTSAMLTVRALPIKFTEGLRNEEATEGATAVLRCELSKMAPV 3655

Query: 488  KWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAKVHVIDPP 547
            +W K    +++ DR  +   G   +L I   + ED G+Y+        +    V  +  P
Sbjct: 3656 EWWKGHETLRDGDRHSLRQDGARCELQIRGLVAEDAGEYLCMCGKERTSAMLTVRAM--P 3713

Query: 548  KIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEG 594
               ++GL  +       G+   L   +S   P +  W +G + + +G
Sbjct: 3714 SKFIEGLRNEEAT---EGDTATLWCELSKAAPVE--WRKGHETLRDG 3755



 Score =  105 bits (263), Expect = 2e-22
 Identities = 95/351 (27%), Positives = 155/351 (44%), Gaps = 14/351 (3%)

Query: 293  GRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAG 352
            G   F  EL+    EV+W  NG  +   + +   HKG +  L + + Q  D      ++ 
Sbjct: 2573 GWASFSCELSHEDEEVEWSLNGMPLYNDSFHEISHKGRRHTLVLKSIQRADAGIVRASSL 2632

Query: 353  DEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKS 412
                S  L VR  P++  K L+D +A     + L+CEVS+ +A+V W K+G ++  GP  
Sbjct: 2633 KVSTSARLEVRVKPVVFLKALDDLSAEERGTLALQCEVSDPEAHVVWRKDGVQL--GPSD 2690

Query: 413  RYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLG 472
            +Y          L++   +  DA  Y+      ++ A++ V    + I   L    V  G
Sbjct: 2691 KYDFLHTAGTRGLVVHDVSPEDAGLYTCHVGSEETRARVRVHDLHVGITKRLKTMEVLEG 2750

Query: 473  KEICLKCEISE---NIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFA 529
            +    +C +S    + P  WT  G  V  S R +   +GR + LV+  A   D G+ VF+
Sbjct: 2751 ESCSFECVLSHESASDPAMWTVGGKTVGSSSRFQATRQGRKYILVVREAAPSDAGEVVFS 2810

Query: 530  PDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDK 589
                 +T  A + V + P  I+  L+ D  V      +LR E+  +G P     W +  K
Sbjct: 2811 --VRGLTSKASLIVRERPAAIIKPLE-DQWVAPGEDVELRCELSRAGTP---VHWLKDRK 2864

Query: 590  AIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVK 640
            AI + S +         + LVI  A   D+G Y   +  EA ++ AS+ V+
Sbjct: 2865 AIRK-SQKYDVVCEGTMAMLVIRGASLKDAGEYTCEV--EASKSTASLHVE 2912



 Score =  105 bits (262), Expect = 2e-22
 Identities = 71/245 (28%), Positives = 111/245 (45%), Gaps = 7/245 (2%)

Query: 290  DKGGRVRFVVELADPK--LEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEY 347
            + G   R   +L+D +    V+W K G E+    KY    +G  R L I+  +  D  EY
Sbjct: 4080 ETGDIARLCCQLSDAESGAVVQWLKEGVELHAGPKYEMRSQGATRELLIHQLEAKDTGEY 4139

Query: 348  YVTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDAN-VKWFKNGEEI 406
                G +K +  L V EP + + + L D      E VE  CEVS   A  V+W   G  +
Sbjct: 4140 ACVTGGQKTAASLRVTEPEVTIVRGLVDAEVTADEDVEFSCEVSRAGATGVQWCLQGLPL 4199

Query: 407  IPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTD 466
                 +   +R +G+ H L ++G T  DA   S       SSA+L+V    + IL PL D
Sbjct: 4200 QSNEVTEVAVR-DGRIHTLRLKGVTPEDAGTVSFHLGNHASSAQLTVRAPEVTILEPLQD 4258

Query: 467  QTVNLGKEICLKCEIS--ENIPGKWTKNGLPVQESDRLKV-VHKGRIHKLVIANALTEDE 523
              ++ G++   +C +S       +W   G+P+Q ++   + V +G +H L +     ED 
Sbjct: 4259 VQLSEGQDASFQCRLSRASGQEARWALGGVPLQANEMNDITVEQGTLHLLTLHKVTLEDA 4318

Query: 524  GDYVF 528
            G   F
Sbjct: 4319 GTVSF 4323



 Score =  105 bits (261), Expect = 3e-22
 Identities = 90/364 (24%), Positives = 150/364 (41%), Gaps = 12/364 (3%)

Query: 288  QVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEY 347
            Q   G       E+A  + EV WYK+G+++  S+K   E  GC R L +         EY
Sbjct: 1453 QAQAGASTTLSCEVAQAQTEVMWYKDGKKLSFSSKVRMEAVGCTRRLVVQQAGQAVAGEY 1512

Query: 348  YVTAGDEKCSTELFVREPPIMVTKQ---LEDTTAYCGERVELECEVSEDDANVKWFKNGE 404
               AG ++ S  L V EP  +  K+     +  A  G    L CEV++    V W+K+G+
Sbjct: 1513 SCEAGSQRLSFHLHVAEPKAVFAKEQPASREVQAEAGTSATLSCEVAQAQTEVTWYKDGK 1572

Query: 405  EIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPL---KIL 461
            ++     S+ R+   G    L+++ A +ADA EYS      + S  L V    +   K  
Sbjct: 1573 KL--SSSSKVRMEAVGCTRRLVVQEAGQADAGEYSCKAGDQRLSFHLHVAEPKVVFAKEQ 1630

Query: 462  TPLTDQTVNLGKEICLKCEISE-NIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALT 520
                +     G    L CE+++      W K+G  +  S +++V   G   +LV+  A  
Sbjct: 1631 PAHREVQAEAGASATLSCEVAQAQTEVTWYKDGKKLSSSSKVRVEAVGCTRRLVVQQAGQ 1690

Query: 521  EDEGDYVFAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPP 580
             D G+Y  + +A    L  ++HV +    I +       + V     + L   ++     
Sbjct: 1691 ADAGEY--SCEAGGQRLSFRLHVAELEPQISERPCRREPLVVKEHEDIILTATLATPSAA 1748

Query: 581  KAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVK 640
               W + D   +  S R  T S  D+ TL +  A+  DS +Y   +  E  +    ++  
Sbjct: 1749 TVTWLK-DGVEIRRSKRHETASQGDTHTLTVHGAQVLDSAIYSCRVGAEGQDFPVQVEEV 1807

Query: 641  VVDF 644
               F
Sbjct: 1808 AAKF 1811



 Score =  105 bits (261), Expect = 3e-22
 Identities = 89/366 (24%), Positives = 152/366 (41%), Gaps = 16/366 (4%)

Query: 288  QVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEY 347
            Q ++G       EL++P   V W K G +++ + +     +GC   L + + Q  D  EY
Sbjct: 3900 QAEEGSTATLQCELSEPTATVVWSKGGLQLQANGRREPRLQGCTAELVLQDLQREDTGEY 3959

Query: 348  YVTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEII 407
              T G +  S  L V   P+   ++L+      G    L CE+S   A+V+W K   ++ 
Sbjct: 3960 TCTCGSQATSATLTVTAAPVRFLRELQHQEVDEGGTAHLCCELSRAGASVEWRKGSLQLF 4019

Query: 408  PGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQ 467
            P  K  Y++  +G    L++ G  + DA +Y+  T   QS A LSV +   K  T L   
Sbjct: 4020 PCAK--YQMVQDGAAAELLVRGVEQEDAGDYTCDTGHTQSMASLSVRVPRPKFKTRLQSL 4077

Query: 468  TVNLGKEICLKCEISENIPG---KWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEG 524
                G    L C++S+   G   +W K G+ +    + ++  +G   +L+I     +D G
Sbjct: 4078 EQETGDIARLCCQLSDAESGAVVQWLKEGVELHAGPKYEMRSQGATRELLIHQLEAKDTG 4137

Query: 525  DYVFAPDAYNVTLPAKVHVIDPPKIILDGL-DADNTVTVIAGNKLRLEIPISGEPPPKAM 583
            +Y            A + V +P   I+ GL DA+    V A   +     +S        
Sbjct: 4138 EYACVTGGQKTA--ASLRVTEPEVTIVRGLVDAE----VTADEDVEFSCEVSRAGATGVQ 4191

Query: 584  WSRGDKAIMEGSGRIRTESYPDS--STLVIDIAERDDSGVYHINLKNEAGEAHASIKVKV 641
            W    + +   S  +   +  D    TL +     +D+G    +L N A  A  +++   
Sbjct: 4192 WCL--QGLPLQSNEVTEVAVRDGRIHTLRLKGVTPEDAGTVSFHLGNHASSAQLTVRAPE 4249

Query: 642  VDFPDP 647
            V   +P
Sbjct: 4250 VTILEP 4255



 Score =  104 bits (259), Expect = 5e-22
 Identities = 89/333 (26%), Positives = 142/333 (42%), Gaps = 10/333 (3%)

Query: 308  VKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTELFVREPPI 367
            V+WYK+   + PS K+    +G    L I      D   Y   AG    STE+ V    +
Sbjct: 2499 VQWYKDDTPLSPSEKFKMSLEGQMAELRILRLMPADAGVYRCQAGSAHSSTEVTVEAREV 2558

Query: 368  MVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILII 427
             VT  L+D  A         CE+S +D  V+W  NG  +     S + I  +G++H L++
Sbjct: 2559 TVTGPLQDAEATEEGWASFSCELSHEDEEVEWSLNGMPLY--NDSFHEISHKGRRHTLVL 2616

Query: 428  EGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCEISE-NIP 486
            +   +ADA      +    +SA+L V +KP+  L  L D +      + L+CE+S+    
Sbjct: 2617 KSIQRADAGIVRASSLKVSTSARLEVRVKPVVFLKALDDLSAEERGTLALQCEVSDPEAH 2676

Query: 487  GKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAKVHVIDP 546
              W K+G+ +  SD+   +H      LV+ +   ED G Y     +      A+V V D 
Sbjct: 2677 VVWRKDGVQLGPSDKYDFLHTAGTRGLVVHDVSPEDAGLYTCHVGSEETR--ARVRVHDL 2734

Query: 547  PKIILDGLDADNTVTVIAGNKLRLEIPISGE-PPPKAMWSRGDKAIMEGSGRIRTESYPD 605
               I   L    T+ V+ G     E  +S E     AMW+ G K +   S R +      
Sbjct: 2735 HVGITKRL---KTMEVLEGESCSFECVLSHESASDPAMWTVGGKTV-GSSSRFQATRQGR 2790

Query: 606  SSTLVIDIAERDDSGVYHINLKNEAGEAHASIK 638
               LV+  A   D+G    +++    +A   ++
Sbjct: 2791 KYILVVREAAPSDAGEVVFSVRGLTSKASLIVR 2823



 Score =  102 bits (253), Expect = 3e-21
 Identities = 86/314 (27%), Positives = 131/314 (41%), Gaps = 13/314 (4%)

Query: 288  QVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEY 347
            +V +GG       L+     VKW      +RP  KY    +G    L + N +  D   Y
Sbjct: 3195 EVLEGGAATLRCVLSSVAAPVKWCYGNNVLRPGDKYSLRQEGAMLELVVRNLRPQDSGRY 3254

Query: 348  YVTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEII 407
              + GD+  S  L V   P     +L +  A  G    L CE+S+  A V+W K  E + 
Sbjct: 3255 SCSFGDQTTSATLTVTALPAQFIGKLRNKEATEGATATLRCELSKA-APVEWRKGSETLR 3313

Query: 408  PGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQ 467
             G   RY +R +G    L I G    DAAEYS +    ++SA L++   P   +  L  Q
Sbjct: 3314 DG--DRYCLRQDGAMCELQIRGLAMVDAAEYSCVCGEERTSASLTIRPMPAHFIGRLRHQ 3371

Query: 468  TVNLGKEICLKCEISENIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDY- 526
                G    L+CE+S+  P +W K    +++ DR  +   G + +L I      D G+Y 
Sbjct: 3372 ESIEGATATLRCELSKAAPVEWRKGRESLRDGDRHSLRQDGAVCELQICGLAVADAGEYS 3431

Query: 527  -VFAPDAYNVTLPAKVHVIDPPKIILDGLDADNTV---TVIAGNKLRLEIPISGEPPPKA 582
             V   +  + TL  K      P    +GL  +  V   T +   +L    P+     P+ 
Sbjct: 3432 CVCGEERTSATLTVKA----LPAKFTEGLRNEEAVEGATAMLWCELSKVAPVEWRKGPEN 3487

Query: 583  MWSRGDKAIMEGSG 596
            +   GD+ I+   G
Sbjct: 3488 L-RDGDRYILRQEG 3500



 Score = 99.8 bits (247), Expect = 1e-20
 Identities = 99/402 (24%), Positives = 162/402 (40%), Gaps = 53/402 (13%)

Query: 278  AFAKILDPAYQVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFIN 337
            +F++ L      +K  +V    EL+ P ++V+W K+G E+R         +G  R L I 
Sbjct: 2167 SFSRPLQDVVTTEKE-KVTLECELSRPNVDVRWLKDGVELRAGKTMAIAAQGACRSLTIY 2225

Query: 338  NCQMTDDSEYYVTAGDEKCST-----------------------------------ELFV 362
             C+  D   Y   A D + S                                    +L V
Sbjct: 2226 RCEFADQGVYVCDAHDAQSSASVKVQGRTYTLIYRRVLAEDAGEIQFVAENAESRAQLRV 2285

Query: 363  REPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKK 422
            +E P+ + + L D  A    R  LEC+VS   A V+WFK  +E+ PGPK  Y +  +G  
Sbjct: 2286 KELPVTLVRPLRDKIAMEKHRGVLECQVSRASAQVRWFKGSQELQPGPK--YELVSDGLY 2343

Query: 423  HILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCE-- 480
              LII      D   Y+      ++SA+  V+ + + I+  L D TV        +CE  
Sbjct: 2344 RKLIISDVHAEDEDTYTCDAGDVKTSAQFFVEEQSITIVRGLQDVTVMEPAPAWFECETS 2403

Query: 481  ISENIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAK 540
            I    P KW      +Q    + +  +G +H+L++    +   G   F       +  A+
Sbjct: 2404 IPSVRPPKWLLGKTVLQAGGNVGLEQEGTVHRLMLRRTCSTMTGPVHFTVGKSRSS--AR 2461

Query: 541  VHVIDPPKIILDGLDADNTVTVIAGNKLR-LEIPISGEPPPKAMWSRGDKAIMEGSGRIR 599
            + V D P ++   L+         G +L+ + +     P PKA+    D   +  S + +
Sbjct: 2462 LVVSDIPVVLTRPLEPK------TGRELQSVVLSCDFRPAPKAVQWYKDDTPLSPSEKFK 2515

Query: 600  TESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKV 641
                   + L I      D+GVY    + +AG AH+S +V V
Sbjct: 2516 MSLEGQMAELRILRLMPADAGVY----RCQAGSAHSSTEVTV 2553



 Score = 96.3 bits (238), Expect = 1e-19
 Identities = 63/220 (28%), Positives = 99/220 (45%), Gaps = 3/220 (1%)

Query: 308  VKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTELFVREPPI 367
            V+W K  + +R   +Y     G +  L I+   + D  EY    G E+ S  L VR P  
Sbjct: 3831 VEWRKGSETLRGGDRYSLRQDGTRCELQIHGLSVADTGEYSCVCGQERTSATLTVRAPQP 3890

Query: 368  MVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILII 427
            +  + L+   A  G    L+CE+SE  A V W K G ++      R   R++G    L++
Sbjct: 3891 VFREPLQSLQAEEGSTATLQCELSEPTATVVWSKGGLQL--QANGRREPRLQGCTAELVL 3948

Query: 428  EGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCEISE-NIP 486
            +   + D  EY+       +SA L+V   P++ L  L  Q V+ G    L CE+S     
Sbjct: 3949 QDLQREDTGEYTCTCGSQATSATLTVTAAPVRFLRELQHQEVDEGGTAHLCCELSRAGAS 4008

Query: 487  GKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDY 526
             +W K  L +    + ++V  G   +L++     ED GDY
Sbjct: 4009 VEWRKGSLQLFPCAKYQMVQDGAAAELLVRGVEQEDAGDY 4048



 Score = 95.1 bits (235), Expect = 3e-19
 Identities = 68/263 (25%), Positives = 113/263 (42%), Gaps = 3/263 (1%)

Query: 264  KRLKRMRREEKKSAAFAKILDPAYQVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKY 323
            +R     R  +K + F++ L  A  + +G  +  V E +   + V W K+G+ +R S + 
Sbjct: 3083 QRASAALRVTEKPSVFSRELTDA-TITEGEDLTLVCETSTCDIPVCWTKDGKTLRGSARC 3141

Query: 324  IFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGER 383
               H+G +  L I    + D   Y   AG    S+ + V   P+   + L+D     G  
Sbjct: 3142 QLSHEGHRAQLLITGATLQDSGRYKCEAGGACSSSIVRVHARPVRFQEALKDLEVLEGGA 3201

Query: 384  VELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTT 443
              L C +S   A VKW      + PG K  Y +R EG    L++      D+  YS    
Sbjct: 3202 ATLRCVLSSVAAPVKWCYGNNVLRPGDK--YSLRQEGAMLELVVRNLRPQDSGRYSCSFG 3259

Query: 444  GGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCEISENIPGKWTKNGLPVQESDRLK 503
               +SA L+V   P + +  L ++    G    L+CE+S+  P +W K    +++ DR  
Sbjct: 3260 DQTTSATLTVTALPAQFIGKLRNKEATEGATATLRCELSKAAPVEWRKGSETLRDGDRYC 3319

Query: 504  VVHKGRIHKLVIANALTEDEGDY 526
            +   G + +L I      D  +Y
Sbjct: 3320 LRQDGAMCELQIRGLAMVDAAEY 3342



 Score = 94.7 bits (234), Expect = 4e-19
 Identities = 70/254 (27%), Positives = 110/254 (43%), Gaps = 5/254 (1%)

Query: 273  EKKSAAFAKILDPAYQVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQR 332
            E+ +A F ++L+P    + GG V    EL+    EV W     ++R   ++    +G  R
Sbjct: 1805 EEVAAKFCRLLEPVCG-ELGGTVTLACELSPACAEVVWRCGNTQLRVGKRFQMVAEGPVR 1863

Query: 333  ILFINNCQMTDDSEYYVTAGDEKCSTELFVREPPIM-VTKQLEDTTAYCGERVELECEVS 391
             L +   +  D  EY   + D+  S +L V  P ++     L    A  G     +C VS
Sbjct: 1864 SLTVLGLRAEDAGEYVCESRDDHTSAQLTVSVPRVVKFMSGLSTVVAEEGGEATFQCVVS 1923

Query: 392  EDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKL 451
              D  V WF++G  + P  K  + I   G  H L I      DA + +V   G  SSA L
Sbjct: 1924 PSDVAVVWFRDGALLQPSEK--FAISQSGASHSLTISDLVLEDAGQITVEAEGASSSAAL 1981

Query: 452  SVDLKPLKILTPLTDQTVNLGKEICLKCEISENIPG-KWTKNGLPVQESDRLKVVHKGRI 510
             V   P+     L  QTV     + L+ E++   P  +WT+N   +     +++  +G  
Sbjct: 1982 RVREAPVLFKKKLEPQTVEERSSVTLEVELTRPWPELRWTRNATALAPGKNVEIHAEGAR 2041

Query: 511  HKLVIANALTEDEG 524
            H+LV+ N    D G
Sbjct: 2042 HRLVLHNVGFADRG 2055



 Score = 94.7 bits (234), Expect = 4e-19
 Identities = 136/633 (21%), Positives = 229/633 (36%), Gaps = 75/633 (11%)

Query: 38   EVSPPSALPPG---LGSRALERKDSDWTLVETPPGEEQAKQNANSQLSILFIEKPQGGTV 94
            E++   A P G   L  R L  KDS     E       A      + S+ F  +    T+
Sbjct: 3049 ELNEIDAQPGGYHVLTLRQLALKDSGTIYFEAGDQRASAALRVTEKPSV-FSRELTDATI 3107

Query: 95   KVGEDITFIAKVKAEDLLRKPTIKWFKGKWMDLASKAGKHLQLKETFERHSRVYTFEMQI 154
              GED+T + +    D+     + W         +K GK L+     +     +  ++ I
Sbjct: 3108 TEGEDLTLVCETSTCDI----PVCW---------TKDGKTLRGSARCQLSHEGHRAQLLI 3154

Query: 155  IKAKDNFAGNYRCEV------------TYKDKFDSCSFDLEVHESTGTTPNIDIRSAFKR 202
              A    +G Y+CE                 +F     DLEV E    T    + S    
Sbjct: 3155 TGATLQDSGRYKCEAGGACSSSIVRVHARPVRFQEALKDLEVLEGGAATLRCVLSSVAAP 3214

Query: 203  SGEGQEDAGELDFSGLLKRREVKQQEEEPQVDVWELLKNAKPSEYEKIAFQYGITDLRGM 262
                     +  +   + R   K    +    +  +++N +P +  + +  +G       
Sbjct: 3215 V--------KWCYGNNVLRPGDKYSLRQEGAMLELVVRNLRPQDSGRYSCSFGDQTTSAT 3266

Query: 263  L-------KRLKRMRREEKKSAAFAKILDPAYQVDKGGRVRFVVELADPKLEVKWYKNGQ 315
            L       + + ++R +E    A A +             R  +  A P   V+W K  +
Sbjct: 3267 LTVTALPAQFIGKLRNKEATEGATATL-------------RCELSKAAP---VEWRKGSE 3310

Query: 316  EIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTELFVREPPIMVTKQLED 375
             +R   +Y     G    L I    M D +EY    G+E+ S  L +R  P     +L  
Sbjct: 3311 TLRDGDRYCLRQDGAMCELQIRGLAMVDAAEYSCVCGEERTSASLTIRPMPAHFIGRLRH 3370

Query: 376  TTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADA 435
              +  G    L CE+S+  A V+W K  E +  G   R+ +R +G    L I G   ADA
Sbjct: 3371 QESIEGATATLRCELSKA-APVEWRKGRESLRDG--DRHSLRQDGAVCELQICGLAVADA 3427

Query: 436  AEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCEISENIPGKWTKNGLP 495
             EYS +    ++SA L+V   P K    L ++    G    L CE+S+  P +W K    
Sbjct: 3428 GEYSCVCGEERTSATLTVKALPAKFTEGLRNEEAVEGATAMLWCELSKVAPVEWRKGPEN 3487

Query: 496  VQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKIILD--G 553
            +++ DR  +  +G   +L I      D G+Y+        +    +  + P + I D   
Sbjct: 3488 LRDGDRYILRQEGTRCELQICGLAMADAGEYLCVCGQERTSATLTIRAL-PARFIEDVKN 3546

Query: 554  LDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDI 613
             +A    T +   +L    P+         W +G + + +G  R           L I  
Sbjct: 3547 QEAREGATAVLQCELNSAAPVE--------WRKGSETLRDGD-RYSLRQDGTKCELQIRG 3597

Query: 614  AERDDSGVYHINLKNEAGEAHASIKVKVVDFPD 646
                D+G Y      E   A  +++   + F +
Sbjct: 3598 LAMADTGEYSCVCGQERTSAMLTVRALPIKFTE 3630



 Score = 93.2 bits (230), Expect = 1e-18
 Identities = 80/337 (23%), Positives = 146/337 (43%), Gaps = 11/337 (3%)

Query: 308  VKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTELFVREPPI 367
            V W K+G EIR S ++    +G    L ++  Q+ D + Y    G E     + V E   
Sbjct: 1750 VTWLKDGVEIRRSKRHETASQGDTHTLTVHGAQVLDSAIYSCRVGAEGQDFPVQVEEVAA 1809

Query: 368  MVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILII 427
               + LE      G  V L CE+S   A V W     ++  G   R+++  EG    L +
Sbjct: 1810 KFCRLLEPVCGELGGTVTLACELSPACAEVVWRCGNTQLRVG--KRFQMVAEGPVRSLTV 1867

Query: 428  EGATKADAAEYSVMTTGGQSSAKLSVDL-KPLKILTPLTDQTVNLGKEICLKCEIS-ENI 485
             G    DA EY   +    +SA+L+V + + +K ++ L+      G E   +C +S  ++
Sbjct: 1868 LGLRAEDAGEYVCESRDDHTSAQLTVSVPRVVKFMSGLSTVVAEEGGEATFQCVVSPSDV 1927

Query: 486  PGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAKVHVID 545
               W ++G  +Q S++  +   G  H L I++ + ED G      +A   +  A + V +
Sbjct: 1928 AVVWFRDGALLQPSEKFAISQSGASHSLTISDLVLEDAGQ--ITVEAEGASSSAALRVRE 1985

Query: 546  PPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPD 605
             P +    L+     TV   + + LE+ ++  P P+  W+R   A+  G   +   +   
Sbjct: 1986 APVLFKKKLEPQ---TVEERSSVTLEVELT-RPWPELRWTRNATALAPGK-NVEIHAEGA 2040

Query: 606  SSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVV 642
               LV+      D G +     ++  +A  +++++ V
Sbjct: 2041 RHRLVLHNVGFADRGFFGCETPDDKTQAKLTVEMRQV 2077



 Score = 90.9 bits (224), Expect = 6e-18
 Identities = 67/274 (24%), Positives = 115/274 (41%), Gaps = 6/274 (2%)

Query: 271  REEKKSAAFAKILDPAYQVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGC 330
            R  +    F K L+P   V++   V   VEL  P  E++W +N   + P        +G 
Sbjct: 1982 RVREAPVLFKKKLEPQ-TVEERSSVTLEVELTRPWPELRWTRNATALAPGKNVEIHAEGA 2040

Query: 331  QRILFINNCQMTDDSEYYVTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEV 390
            +  L ++N    D   +     D+K   +L V    + + + L+   A       +E ++
Sbjct: 2041 RHRLVLHNVGFADRGFFGCETPDDKTQAKLTVEMRQVRLVRGLQAVEAREQGTATMEVQL 2100

Query: 391  SEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAK 450
            S  D +  W ++G     GP     +R  G  H L + G    D+        G  +SA+
Sbjct: 2101 SHADVDGSWTRDGLRFQQGPTCHLAVR--GPMHTLTLSGLRPEDSGLMVFKAEGVHTSAR 2158

Query: 451  LSVDLKPLKILTPLTDQTVNLGKEICLKCEISE-NIPGKWTKNGLPVQESDRLKVVHKGR 509
            L V   P+    PL D      +++ L+CE+S  N+  +W K+G+ ++    + +  +G 
Sbjct: 2159 LVVTELPVSFSRPLQDVVTTEKEKVTLECELSRPNVDVRWLKDGVELRAGKTMAIAAQGA 2218

Query: 510  IHKLVIANALTEDEGDYVFAPDAYNVTLPAKVHV 543
               L I      D+G YV   DA++    A V V
Sbjct: 2219 CRSLTIYRCEFADQGVYVC--DAHDAQSSASVKV 2250



 Score = 90.9 bits (224), Expect = 6e-18
 Identities = 66/241 (27%), Positives = 108/241 (44%), Gaps = 5/241 (2%)

Query: 289  VDKGGRVRFVVELADPKLE-VKWYKNGQEIRPST-KYIFEHKGCQRILFINNCQMTDDSE 346
            V +G    F   ++    E V W+ +   +  +    I    G   +L +    + D   
Sbjct: 3016 VQEGSSATFRCRISPANYEPVHWFLDKTPLHANELNEIDAQPGGYHVLTLRQLALKDSGT 3075

Query: 347  YYVTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEI 406
             Y  AGD++ S  L V E P + +++L D T   GE + L CE S  D  V W K+G+ +
Sbjct: 3076 IYFEAGDQRASAALRVTEKPSVFSRELTDATITEGEDLTLVCETSTCDIPVCWTKDGKTL 3135

Query: 407  IPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTD 466
                 +R ++  EG +  L+I GAT  D+  Y     G  SS+ + V  +P++    L D
Sbjct: 3136 --RGSARCQLSHEGHRAQLLITGATLQDSGRYKCEAGGACSSSIVRVHARPVRFQEALKD 3193

Query: 467  QTVNLGKEICLKCEISE-NIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGD 525
              V  G    L+C +S    P KW      ++  D+  +  +G + +LV+ N   +D G 
Sbjct: 3194 LEVLEGGAATLRCVLSSVAAPVKWCYGNNVLRPGDKYSLRQEGAMLELVVRNLRPQDSGR 3253

Query: 526  Y 526
            Y
Sbjct: 3254 Y 3254



 Score = 88.2 bits (217), Expect = 4e-17
 Identities = 88/374 (23%), Positives = 146/374 (39%), Gaps = 11/374 (2%)

Query: 273  EKKSAAFAKILDPAYQVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQR 332
            E+K+  F + L    QV++ G   F  +   P   V W K   E+R S K+    +G   
Sbjct: 2912 EEKANCFTEELTNL-QVEEKGTAVFTCKTEHPAATVTWRKGLLELRASGKHQPSQEGLTL 2970

Query: 333  ILFINNCQMTDDSEYYVTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSE 392
             L I+  +  D   Y    G  +   +L V+   + + + LED     G      C +S 
Sbjct: 2971 RLTISALEKADSDTYTCDIGQAQSRAQLLVQGRRVHIIEDLEDVDVQEGSSATFRCRISP 3030

Query: 393  DDAN-VKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKL 451
             +   V WF +   +     +    +  G  H+L +      D+          ++SA L
Sbjct: 3031 ANYEPVHWFLDKTPLHANELNEIDAQ-PGGYHVLTLRQLALKDSGTIYFEAGDQRASAAL 3089

Query: 452  SVDLKPLKILTPLTDQTVNLGKEICLKCEISE-NIPGKWTKNGLPVQESDRLKVVHKGRI 510
             V  KP      LTD T+  G+++ L CE S  +IP  WTK+G  ++ S R ++ H+G  
Sbjct: 3090 RVTEKPSVFSRELTDATITEGEDLTLVCETSTCDIPVCWTKDGKTLRGSARCQLSHEGHR 3149

Query: 511  HKLVIANALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRL 570
             +L+I  A  +D G Y         +   +VH   P +      +A   + V+ G    L
Sbjct: 3150 AQLLITGATLQDSGRYKCEAGGACSSSIVRVHA-RPVRF----QEALKDLEVLEGGAATL 3204

Query: 571  EIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEA 630
               +S    P   W  G+  +  G  +           LV+      DSG Y  +  ++ 
Sbjct: 3205 RCVLSSVAAP-VKWCYGNNVLRPGD-KYSLRQEGAMLELVVRNLRPQDSGRYSCSFGDQT 3262

Query: 631  GEAHASIKVKVVDF 644
              A  ++      F
Sbjct: 3263 TSATLTVTALPAQF 3276



 Score = 85.9 bits (211), Expect = 2e-16
 Identities = 87/375 (23%), Positives = 152/375 (40%), Gaps = 17/375 (4%)

Query: 286 AYQVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMT-DD 344
           A Q  +GG V F V+L       +W+ +GQ ++ S+ Y       +  L I     +   
Sbjct: 621 AVQAVEGGEVTFSVDLTVASAG-EWFLDGQALKASSVYEIHCDRTRHTLTIREVPASLHG 679

Query: 345 SEYYVTAGDEKCSTELFVREPPIMVTKQ-----LEDTTAYCGERVELECEVSEDDANVKW 399
           ++    A   + S  + VR  P +   +       +  A   E  +L  E+S+  A V W
Sbjct: 680 AQLKFVANGIESSIRMEVRAAPGLTANKPPAAAAREVLARLHEEAQLLAELSDQAAAVTW 739

Query: 400 FKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLK 459
            K+G  + PGPK  Y ++    + +L++    + DA  Y  ++ GG+ + +LSV      
Sbjct: 740 LKDGRTLSPGPK--YEVQASAGRRVLLVRDVARDDAGLYECVSRGGRIAYQLSVQGLARF 797

Query: 460 ILTPLTDQTVN--LGKEICLKCEISE-NIPGKWTKNGLPVQES-DRLKVVHKGRIHKLVI 515
           +   +    V+   G     +CE SE ++   W K+G+ +  S +R      G  H+LV 
Sbjct: 798 LHKDMAGSCVDAVAGGPAQFECETSEAHVHVHWYKDGMELGHSGERFLQEDVGTRHRLVA 857

Query: 516 ANALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPIS 575
           A    +DEG Y       +V    ++ V +P  +      A   +   AG    L   ++
Sbjct: 858 ATVTRQDEGTYSCRVGEDSVDF--RLRVSEPKVVFAKEQLARRKLQAEAGASATLSCEVA 915

Query: 576 GEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHA 635
                   +  G K  +  S ++  E+   +  LV+  A + D+G Y      +    H 
Sbjct: 916 QAQTEVTWYKDGKK--LSSSSKVCMEATGCTRRLVVQQAGQADAGEYSCEAGGQRLSFHL 973

Query: 636 SIKVKVVDFPDPPVA 650
            +K   V F    VA
Sbjct: 974 DVKEPKVVFAKDQVA 988



 Score = 84.7 bits (208), Expect = 5e-16
 Identities = 88/394 (22%), Positives = 152/394 (38%), Gaps = 36/394 (9%)

Query: 352  GDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDAN-VKWFKNGEEIIPGP 410
            G+   S +L VR P + + + L+D     G+    +C +S       +W   G  +    
Sbjct: 4235 GNHASSAQLTVRAPEVTILEPLQDVQLSEGQDASFQCRLSRASGQEARWALGGVPLQANE 4294

Query: 411  KSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVN 470
             +   +  +G  H+L +   T  DA   S       S A+L V  K   ++  L +    
Sbjct: 4295 MNDITVE-QGTLHLLTLHKVTLEDAGTVSFHVGTCSSEAQLKVTAKNT-VVRGLENVEAL 4352

Query: 471  LGKEICLKCEIS--ENIPGKWTKNGLPVQESDRLKVV--HKGRIHKLVIANALTEDEGDY 526
             G E   +C++S  E     W  +  PV  S+  +VV    G  H L++ N   +D    
Sbjct: 4353 EGGEALFECQLSQPEVAAHTWLLDDEPVHTSENAEVVFFENGLRHLLLLKNLRPQDSCRV 4412

Query: 527  VF-----APDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPIS-GEPPP 580
             F        A+      ++ +++P K             V AG +      +S   P  
Sbjct: 4413 TFLAGDMVTSAFLTVRGWRLEILEPLK----------NAAVRAGAQACFTCTLSEAVPVG 4462

Query: 581  KAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVK 640
            +A W     A+          +      L++  A+   +G      +    +A AS ++ 
Sbjct: 4463 EASWYINGAAVQPDDSDWTVTADGSHHALLLRSAQPHHAGEVTFACR----DAVASARLT 4518

Query: 641  VVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCK 700
            V+  PDPP    V         ++W  P  DGG  + GY +E K+  + +W      LC 
Sbjct: 4519 VLGLPDPPEDAEVVARSSHTVTLSWAAPMSDGGGGLCGYRVEVKEGATGQWR-----LCH 4573

Query: 701  ETTFEPKKMIEGVA----YEVRIFAVNAIGISKP 730
            E    P+ +++G+A    Y  R+ AV  +G  +P
Sbjct: 4574 ELVPGPECVVDGLAPGETYRFRVAAVGPVGAGEP 4607



 Score = 82.0 bits (201), Expect = 3e-15
 Identities = 75/342 (21%), Positives = 139/342 (40%), Gaps = 15/342 (4%)

Query: 296  RFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEK 355
            + + EL+D    V W K+G+ + P  KY  +    +R+L + +    D   Y   +   +
Sbjct: 725  QLLAELSDQAAAVTWLKDGRTLSPGPKYEVQASAGRRVLLVRDVARDDAGLYECVSRGGR 784

Query: 356  CSTELFVREPPIMVTKQLEDT--TAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSR 413
             + +L V+     + K +  +   A  G   + ECE SE   +V W+K+G E +     R
Sbjct: 785  IAYQLSVQGLARFLHKDMAGSCVDAVAGGPAQFECETSEAHVHVHWYKDGME-LGHSGER 843

Query: 414  YRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQT----- 468
            +     G +H L+    T+ D   YS     G+ S    + +   K++            
Sbjct: 844  FLQEDVGTRHRLVAATVTRQDEGTYSCRV--GEDSVDFRLRVSEPKVVFAKEQLARRKLQ 901

Query: 469  VNLGKEICLKCEISE-NIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYV 527
               G    L CE+++      W K+G  +  S ++ +   G   +LV+  A   D G+Y 
Sbjct: 902  AEAGASATLSCEVAQAQTEVTWYKDGKKLSSSSKVCMEATGCTRRLVVQQAGQADAGEY- 960

Query: 528  FAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRG 587
             + +A    L   + V +P  +      A + V   AG    L   ++ +   + MW + 
Sbjct: 961  -SCEAGGQRLSFHLDVKEPKVVFAKDQVAHSEVQAEAGASATLSCEVA-QAQTEVMWYKD 1018

Query: 588  DKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNE 629
             K  +  S ++  E+      LV+  A + D+G Y    + +
Sbjct: 1019 GKK-LSSSLKVHVEAKGCRRRLVVQQAGKTDAGDYSCEARGQ 1059



 Score = 79.0 bits (193), Expect = 2e-14
 Identities = 93/405 (22%), Positives = 153/405 (37%), Gaps = 59/405 (14%)

Query: 291  KGGRVRFVVELADPKLEVK-WYKNGQEIRPS--TKYIFEHKGCQRILFINNCQMTDDSEY 347
            +GG   F  +L+ P++    W  + + +  S   + +F   G + +L + N +  D    
Sbjct: 4353 EGGEALFECQLSQPEVAAHTWLLDDEPVHTSENAEVVFFENGLRHLLLLKNLRPQDSCRV 4412

Query: 348  YVTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSE--DDANVKWFKNGEE 405
               AGD   S  L VR   + + + L++     G +    C +SE        W+ NG  
Sbjct: 4413 TFLAGDMVTSAFLTVRGWRLEILEPLKNAAVRAGAQACFTCTLSEAVPVGEASWYINGAA 4472

Query: 406  IIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSV----DLKPLKIL 461
            + P   S + +  +G  H L++  A    A E +       +SA+L+V    D      +
Sbjct: 4473 VQPDD-SDWTVTADGSHHALLLRSAQPHHAGEVTFACRDAVASARLTVLGLPDPPEDAEV 4531

Query: 462  TPLTDQTVNL---------GKEIC-LKCEISENIPGKW------------TKNGLPVQES 499
               +  TV L         G  +C  + E+ E   G+W              +GL   E+
Sbjct: 4532 VARSSHTVTLSWAAPMSDGGGGLCGYRVEVKEGATGQWRLCHELVPGPECVVDGLAPGET 4591

Query: 500  DRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKIILDGLDADNT 559
             R +V   G +                        V LP  V + +PPK +     A  +
Sbjct: 4592 YRFRVAAVGPVGA-------------------GEPVHLPQTVRLAEPPKPVPPQPSAPES 4632

Query: 560  VTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDS 619
              V AG  + LE+ +  E   + +W +G + I  G GR    S      LVI     +D 
Sbjct: 4633 RQVAAGEDVSLELEVVAE-AGEVIWHKGMERIQPG-GRFEVVSQGRQQMLVIKGFTAEDQ 4690

Query: 620  GVYHINL-KNEAGEAHASIKV-----KVVDFPDPPVAPTVTEVGD 658
            G YH  L +     A A+ +V      V + P P + P   + GD
Sbjct: 4691 GEYHCGLAQGSICPAAATFQVALSPASVDEAPQPSLPPEAAQEGD 4735



 Score = 75.9 bits (185), Expect = 2e-13
 Identities = 76/288 (26%), Positives = 112/288 (38%), Gaps = 25/288 (8%)

Query: 257 TDLRGMLKRLKRMRREEKKSAAFAKILDPAYQVDKGGRVRFVVE----------LADPKL 306
           T    +L  L+R R   +   A      PA     G R   V E            +PK 
Sbjct: 214 TSTAALLAHLQRRREAMRAEGA------PASPPSTGTRTCTVTEGKHARLSCYVTGEPKP 267

Query: 307 EVKWYKNGQEIRPSTKYI-FEHKGCQRILFINNCQMTDDSEYYVTA----GDEKCSTELF 361
           E  W K+GQ +    +++ +E      +L I  C+ +D   Y  TA    G    S  + 
Sbjct: 268 ETVWKKDGQLVTEGRRHVVYEDAQENFVLKILFCKQSDRGLYTCTASNLVGQTYSSVLVV 327

Query: 362 VREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGK 421
           VREP +   K+L+D      E     CEV +      WFK  EE      ++Y I  EG 
Sbjct: 328 VREPAVPFKKRLQDLEVREKESATFLCEVPQPSTEAAWFK--EETRLWASAKYGIEEEGT 385

Query: 422 KHILIIEGATKADAAEYSVMT-TGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCE 480
           +  L +   +  D A Y   T  G ++ A+L+V    L+ L   T   V      C++  
Sbjct: 386 ERRLTVRNVSADDDAVYICETPEGSRTVAELAVQGNLLRKLPRKTAVRVGDTAMFCVELA 445

Query: 481 ISENIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVF 528
           +    P  W +N   V    R+ +  +G  H L I+    ED G   F
Sbjct: 446 VPVG-PVHWLRNQEEVVAGGRVAISAEGTRHTLTISQCCLEDVGQVAF 492



 Score = 67.0 bits (162), Expect = 1e-10
 Identities = 60/217 (27%), Positives = 84/217 (38%), Gaps = 33/217 (15%)

Query: 264 KRLKRMRREEKKSAAFAKILDPAYQVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKY 323
           KRL+ +   EK+SA F                  + E+  P  E  W+K    +  S KY
Sbjct: 337 KRLQDLEVREKESATF------------------LCEVPQPSTEAAWFKEETRLWASAKY 378

Query: 324 IFEHKGCQRILFINNCQMTDDSEYYV-TAGDEKCSTELFV-----REPPIMVTKQLEDTT 377
             E +G +R L + N    DD+ Y   T    +   EL V     R+ P     ++ DT 
Sbjct: 379 GIEEEGTERRLTVRNVSADDDAVYICETPEGSRTVAELAVQGNLLRKLPRKTAVRVGDTA 438

Query: 378 AYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAE 437
            +C   VEL   V      V W +N EE++ G   R  I  EG +H L I      D  +
Sbjct: 439 MFC---VELAVPVGP----VHWLRNQEEVVAG--GRVAISAEGTRHTLTISQCCLEDVGQ 489

Query: 438 YSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKE 474
            + M    Q+S +  V       L P  D  V    E
Sbjct: 490 VAFMAGDCQTSTQFCVSAPRKPPLQPPVDPVVKARME 526



 Score = 64.3 bits (155), Expect = 6e-10
 Identities = 72/308 (23%), Positives = 115/308 (37%), Gaps = 50/308 (16%)

Query: 381 GERVELECE-VSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYS 439
           G+   L C+ V      V W K+ + +  G  +R+R+  +G  + L I      D+ +Y 
Sbjct: 24  GKDATLSCQIVGNPTPQVSWEKDQQPVAAG--ARFRLAQDGDLYRLTILDLALGDSGQYV 81

Query: 440 VMTTGGQSSAKLSVDLK-----------PLKILTPLTDQTVNLGKEICLKCEI--SENIP 486
                    A  +V L+           P  +L P T   V  G E   +C +  S    
Sbjct: 82  CRARNAIGEAFAAVGLQVDAEAACAEQAPHFLLRP-TSIRVREGSEATFRCRVGGSPRPA 140

Query: 487 GKWTKNGLPVQESD--RLKVVHKGRIHKLVIANALTEDEGDY-VFAPDAYNVTLPAKVHV 543
             W+K+G  + E D  R++V   G    L I  A   D G Y V A +       A   V
Sbjct: 141 VSWSKDGRRLGEPDGPRVRVEELGEASALRIRAARPRDGGTYEVRAENPLGAASAAAALV 200

Query: 544 IDPPK------------------------IILDGLDAD------NTVTVIAGNKLRLEIP 573
           +D                           +  +G  A        T TV  G   RL   
Sbjct: 201 VDSDAADTASRPGTSTAALLAHLQRRREAMRAEGAPASPPSTGTRTCTVTEGKHARLSCY 260

Query: 574 ISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEA 633
           ++GEP P+ +W +  + + EG   +  E   ++  L I   ++ D G+Y     N  G+ 
Sbjct: 261 VTGEPKPETVWKKDGQLVTEGRRHVVYEDAQENFVLKILFCKQSDRGLYTCTASNLVGQT 320

Query: 634 HASIKVKV 641
           ++S+ V V
Sbjct: 321 YSSVLVVV 328



 Score = 63.9 bits (154), Expect = 8e-10
 Identities = 52/197 (26%), Positives = 83/197 (42%), Gaps = 12/197 (6%)

Query: 469 VNLGKEICLKCEISENIPGK--WTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDY 526
           V++GK+  L C+I  N   +  W K+  PV    R ++   G +++L I +    D G Y
Sbjct: 21  VSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQDGDLYRLTILDLALGDSGQY 80

Query: 527 VF-APDAYNVTLPAKVHVIDPPKIILDG----LDADNTVTVIAGNKLRLEIPISGEPPPK 581
           V  A +A      A    +D      +     L    ++ V  G++      + G P P 
Sbjct: 81  VCRARNAIGEAFAAVGLQVDAEAACAEQAPHFLLRPTSIRVREGSEATFRCRVGGSPRPA 140

Query: 582 AMWSRGDKAIMEGSG-RIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVK 640
             WS+  + + E  G R+R E   ++S L I  A   D G Y +  +N  G A A+  + 
Sbjct: 141 VSWSKDGRRLGEPDGPRVRVEELGEASALRIRAARPRDGGTYEVRAENPLGAASAAAALV 200

Query: 641 VVDFPDPPVAPTVTEVG 657
           V    D   A T +  G
Sbjct: 201 V----DSDAADTASRPG 213



 Score = 56.6 bits (135), Expect = 1e-07
 Identities = 50/185 (27%), Positives = 82/185 (44%), Gaps = 12/185 (6%)

Query: 464  LTDQTVNLGKEICLKCEISENIPG--KWTKNGLPVQESDRLKVVHKGRIHKLVIANALTE 521
            L D T  LG+ + L C ++        W K+G  VQ      ++        +I ++LT 
Sbjct: 6020 LADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCALILDSLTG 6079

Query: 522  -DEGDYVF--APDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEP 578
             D G Y+   A  A N +   K+ V  PP+ +    +       + G   +    I G P
Sbjct: 6080 VDSGQYMCFAASAAGNCSTLGKILVQVPPRFV----NKVRASPFVEGEDAQFTCTIEGAP 6135

Query: 579  PPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDI--AERDDSGVYHINLKNEAGEAHAS 636
             P+  W + D A++    + +T S P S  LV+ I  A ++D G+Y   L N  G A AS
Sbjct: 6136 YPQIRWYK-DGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYECELVNRLGSARAS 6194

Query: 637  IKVKV 641
             ++++
Sbjct: 6195 AELRI 6199



 Score = 54.7 bits (130), Expect = 5e-07
 Identities = 60/290 (20%), Positives = 103/290 (35%), Gaps = 29/290 (10%)

Query: 839  EIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEI--DKNQINIRN 896
            EI+EP        LK   +R   +A       +  P  E +W  +GA +  D +   +  
Sbjct: 4433 EILEP--------LKNAAVRAGAQACFTCTLSEAVPVGEASWYINGAAVQPDDSDWTVTA 4484

Query: 897  SETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVA 956
              +   + +R A+  H+G+     +       AS  + ++  P PP+  ++       V 
Sbjct: 4485 DGSHHALLLRSAQPHHAGEVTFACRD----AVASARLTVLGLPDPPEDAEVVARSSHTVT 4540

Query: 957  LTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSEN 1016
            L+W  P  DG   + GY ++  +  + +W    E        +  L  G  Y FRV +  
Sbjct: 4541 LSWAAPMSDGGGGLCGYRVEVKEGATGQWRLCHELVPGPECVVDGLAPGETYRFRVAAVG 4600

Query: 1017 MCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCS 1076
              G  E   + +   +      +   P         AP   Q        AG + +L   
Sbjct: 4601 PVGAGEPVHLPQTVRLAEPPKPVPPQP--------SAPESRQ------VAAGEDVSLELE 4646

Query: 1077 VRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCC 1126
            V      ++ W K    I    R+ + S      L I+  +  D G Y C
Sbjct: 4647 VVAE-AGEVIWHKGMERIQPGGRFEVVSQGRQQMLVIKGFTAEDQGEYHC 4695



 Score = 53.9 bits (128), Expect = 9e-07
 Identities = 31/95 (32%), Positives = 51/95 (53%), Gaps = 2/95 (2%)

Query: 1050 FSEAPMF-TQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGV 1108
            FS AP F T+P     ++ G +ATL+C + GNP P+++W K++  +    R+R+  +  +
Sbjct: 6    FSGAPRFLTRPKAFVVSV-GKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQDGDL 64

Query: 1109 CTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1143
              L I   +  D G Y C+A N +G       L+V
Sbjct: 65   YRLTILDLALGDSGQYVCRARNAIGEAFAAVGLQV 99



 Score = 53.5 bits (127), Expect = 1e-06
 Identities = 117/569 (20%), Positives = 219/569 (38%), Gaps = 75/569 (13%)

Query: 381 GERVELECEVS-EDDANVKWFKNGEEIIPGPKSRYRIRVEGKKH-ILIIEGATKADAAEY 438
           G+   L C V+ E      W K+G+ +  G   R+ +  + +++ +L I    ++D   Y
Sbjct: 252 GKHARLSCYVTGEPKPETVWKKDGQLVTEG--RRHVVYEDAQENFVLKILFCKQSDRGLY 309

Query: 439 SVMTTG--GQSSAKLSVDLKP--LKILTPLTDQTVNLGKEICLKCEISE-NIPGKWTKNG 493
           +   +   GQ+ + + V ++   +     L D  V   +     CE+ + +    W K  
Sbjct: 310 TCTASNLVGQTYSSVLVVVREPAVPFKKRLQDLEVREKESATFLCEVPQPSTEAAWFKEE 369

Query: 494 LPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVF-APDAYNVTLPAKVHVIDPPKIILD 552
             +  S +  +  +G   +L + N   +D+  Y+   P+         V        +L 
Sbjct: 370 TRLWASAKYGIEEEGTERRLTVRNVSADDDAVYICETPEGSRTVAELAVQ-----GNLLR 424

Query: 553 GLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVID 612
            L     V V       +E+ +   P     W R  + ++ G GR+   +     TL I 
Sbjct: 425 KLPRKTAVRVGDTAMFCVELAV---PVGPVHWLRNQEEVVAG-GRVAISAEGTRHTLTIS 480

Query: 613 IAERDDSGVYHINLKNEAGEAHASIKVKVVDFP-----DPPVAPTVTEVGDDWCIMNWEP 667
               +D G     +   AG+   S +   V  P      PPV P V    +   I++W P
Sbjct: 481 QCCLEDVG----QVAFMAGDCQTSTQF-CVSAPRKPPLQPPVDPVVKARMESSVILSWSP 535

Query: 668 PAYDGGSPIL--GYFIERKKKQSSRWMRLNFDLCKETTF--EPKKMIEGVA----YEVRI 719
           P + G  P+   GY +E+KK  +  W+R     C E  +   P+  +  VA    ++ R+
Sbjct: 536 PPH-GERPVTIDGYLVEKKKLGTYTWIR-----CHEAEWVATPELTVADVAEEGNFQFRV 589

Query: 720 FAVNAIGISKPSMPSRPFV----PLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLD 775
            A+N+ G S P +     V     LAV +P  L  V +V    VT               
Sbjct: 590 SALNSFGQS-PYLEFPGTVHLAPKLAVRTP--LKAVQAVEGGEVT--------------- 631

Query: 776 GYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPI 835
            + ++       +W +  + L   + + I    T   + +R    +  GA + K+ +  I
Sbjct: 632 -FSVDLTVASAGEWFLDGQALKASSVYEIHCDRTRHTLTIREVPASLHGA-QLKFVANGI 689

Query: 836 ---LVKEIIEPPKI---RIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDK 889
              +  E+   P +   + P    +  + R+ E   L+     +    +TW KDG  +  
Sbjct: 690 ESSIRMEVRAAPGLTANKPPAAAAREVLARLHEEAQLLAELSDQ-AAAVTWLKDGRTLSP 748

Query: 890 N-QINIRNSETDTIIFIRKAERSHSGKYD 917
             +  ++ S    ++ +R   R  +G Y+
Sbjct: 749 GPKYEVQASAGRRVLLVRDVARDDAGLYE 777



 Score = 53.1 bits (126), Expect = 1e-06
 Identities = 32/94 (34%), Positives = 43/94 (45%), Gaps = 2/94 (2%)

Query: 1052 EAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKN--KVAIVDDPRYRMFSNQGVC 1109
            +AP F     +     G  AT  C V G+P+P ++W K+  ++   D PR R+       
Sbjct: 108  QAPHFLLRPTSIRVREGSEATFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVEELGEAS 167

Query: 1110 TLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1143
             L IR   P DGGTY  +A N LG       L V
Sbjct: 168  ALRIRAARPRDGGTYEVRAENPLGAASAAAALVV 201



 Score = 51.6 bits (122), Expect = 4e-06
 Identities = 30/92 (32%), Positives = 42/92 (45%), Gaps = 1/92 (1%)

Query: 1053 APMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSN-QGVCTL 1111
            AP+F   L N     GY  + +C V G P P + W K+   + +D  Y +  + QG   L
Sbjct: 5125 APVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEEDDHYMINEDQQGGHQL 5184

Query: 1112 EIRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1143
             I    P D G Y C A N +G    + +L V
Sbjct: 5185 IITAVVPADMGVYRCLAENSMGVSSTKAELRV 5216



 Score = 50.1 bits (118), Expect = 1e-05
 Identities = 30/93 (32%), Positives = 43/93 (46%), Gaps = 1/93 (1%)

Query: 1054 PMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSN-QGVCTLE 1112
            P F + L +  A  G    L C V G PKP I+W K+  A+  DP + +  +  G C L 
Sbjct: 6014 PDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCALI 6073

Query: 1113 IRKPSPYDGGTYCCKAVNDLGTVEIECKLEVKV 1145
            +   +  D G Y C A +  G      K+ V+V
Sbjct: 6074 LDSLTGVDSGQYMCFAASAAGNCSTLGKILVQV 6106



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 44/156 (28%), Positives = 67/156 (42%), Gaps = 8/156 (5%)

Query: 729  KPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTED 788
            + ++ S     L +  PP    V + +  TVT+ W  P   G  GL GY +E     T  
Sbjct: 4509 RDAVASARLTVLGLPDPPEDAEVVARSSHTVTLSWAAPMSDGGGGLCGYRVEVKEGATGQ 4568

Query: 789  WIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRI 848
            W + + +L+   +  + GL        RV AV   GA EP +  Q +    + EPPK  +
Sbjct: 4569 WRLCH-ELVPGPECVVDGLAPGETYRFRVAAVGPVGAGEPVHLPQTV---RLAEPPK-PV 4623

Query: 849  PRHLKQTYIRRV--GEAVNLVIPFQGKPRPELTWKK 882
            P        R+V  GE V+L +    +   E+ W K
Sbjct: 4624 PPQPSAPESRQVAAGEDVSLELEVVAE-AGEVIWHK 4658



 Score = 48.9 bits (115), Expect = 3e-05
 Identities = 26/93 (27%), Positives = 44/93 (47%), Gaps = 2/93 (2%)

Query: 1054 PMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFS--NQGVCTL 1111
            P F   +  +  + G +A   C++ G P P+I W K+   +    +++  S    G+  L
Sbjct: 6108 PRFVNKVRASPFVEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVL 6167

Query: 1112 EIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVK 1144
             IR  S  D G Y C+ VN LG+     +L ++
Sbjct: 6168 VIRAASKEDLGLYECELVNRLGSARASAELRIQ 6200



 Score = 48.1 bits (113), Expect = 5e-05
 Identities = 72/323 (22%), Positives = 123/323 (38%), Gaps = 63/323 (19%)

Query: 238  LLKNAKPSEYEKIAFQYG--ITDLRGMLKRLKRMRREEKKSAAFAKILDPAYQVDKGGRV 295
            LLKN +P +  ++ F  G  +T     ++  +    E  K+AA          V  G + 
Sbjct: 4400 LLKNLRPQDSCRVTFLAGDMVTSAFLTVRGWRLEILEPLKNAA----------VRAGAQA 4449

Query: 296  RFVVELAD--PKLEVKWYKNGQEIRPS-TKYIFEHKGCQRILFINNCQMTDDSEYYVTAG 352
             F   L++  P  E  WY NG  ++P  + +     G    L + + Q     E      
Sbjct: 4450 CFTCTLSEAVPVGEASWYINGAAVQPDDSDWTVTADGSHHALLLRSAQPHHAGEVTFACR 4509

Query: 353  DEKCSTELFVR---EPPI---MVTKQLEDTT------------AYCGERVELECEVSEDD 394
            D   S  L V    +PP    +V +     T              CG RVE++     + 
Sbjct: 4510 DAVASARLTVLGLPDPPEDAEVVARSSHTVTLSWAAPMSDGGGGLCGYRVEVK-----EG 4564

Query: 395  ANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGG--------- 445
            A  +W +   E++PGP+              +++G    +   + V   G          
Sbjct: 4565 ATGQW-RLCHELVPGPEC-------------VVDGLAPGETYRFRVAAVGPVGAGEPVHL 4610

Query: 446  QSSAKLSVDLKPLKILTPLTD-QTVNLGKEICLKCEI-SENIPGKWTKNGLPVQESDRLK 503
              + +L+   KP+       + + V  G+++ L+ E+ +E     W K    +Q   R +
Sbjct: 4611 PQTVRLAEPPKPVPPQPSAPESRQVAAGEDVSLELEVVAEAGEVIWHKGMERIQPGGRFE 4670

Query: 504  VVHKGRIHKLVIANALTEDEGDY 526
            VV +GR   LVI     ED+G+Y
Sbjct: 4671 VVSQGRQQMLVIKGFTAEDQGEY 4693



 Score = 48.1 bits (113), Expect = 5e-05
 Identities = 37/159 (23%), Positives = 68/159 (42%), Gaps = 7/159 (4%)

Query: 304  PKLEVKWYKNGQEIRPSTKYI-FEHKGCQRILFINNCQMTDDSEY--YVTAGDEKCST-- 358
            PK  + WYK+G+ ++    +I  E       L +++    D  +Y  +  +    CST  
Sbjct: 6041 PKPVISWYKDGKAVQVDPHHILIEDPDGSCALILDSLTGVDSGQYMCFAASAAGNCSTLG 6100

Query: 359  ELFVREPPIMVTKQLEDTTAYCGERVELECEV-SEDDANVKWFKNGEEIIPGPKSRYRIR 417
            ++ V+ PP  V K +  +    GE  +  C +       ++W+K+G  +  G K +    
Sbjct: 6101 KILVQVPPRFVNK-VRASPFVEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSE 6159

Query: 418  VEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLK 456
                  +L+I  A+K D   Y         SA+ S +L+
Sbjct: 6160 PRSGLLVLVIRAASKEDLGLYECELVNRLGSARASAELR 6198



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 33/114 (28%), Positives = 47/114 (41%), Gaps = 3/114 (2%)

Query: 1023 DATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPK 1082
            D +M K +  I    K YK  V ++    E PMF+    +T A  G    L C V     
Sbjct: 4869 DPSMDKAAVKIQAAFKGYK--VRKEMKQQEGPMFSHTFGDTEAQVGDALRLECVVASKAD 4926

Query: 1083 PKITWMKNKVAIVDDPRYRMFS-NQGVCTLEIRKPSPYDGGTYCCKAVNDLGTV 1135
             +  W+K+ V + D   + +     G C+L I      D G Y C+  N  G V
Sbjct: 4927 VRARWLKDGVELTDGRHHHIDQLGDGTCSLLITGLDRADAGCYTCQVSNKFGQV 4980



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 74/353 (20%), Positives = 126/353 (35%), Gaps = 81/353 (22%)

Query: 366  PIMVTKQLEDTTAYCGERVELECEVS-EDDANVKWFKNGEEIIPGPKSRYRIRVEGKK-H 423
            P+ +T +L++     G  V  +C V+ +   +V+WFK+G+ +       Y I  + +  H
Sbjct: 5126 PVFLT-ELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLL--EEDDHYMINEDQQGGH 5182

Query: 424  ILIIEGATKADAAEYSVMTTGGQ----SSAKLSVDLKPLKILTPL--------------- 464
             LII     AD   Y  +         + A+L VDL      T                 
Sbjct: 5183 QLIITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDYDTAADATESSSYFSAQGYL 5242

Query: 465  -------TDQTVNLGK--EICLKCEISENIPGK------------------WTKNGLPVQ 497
                   T+ T + G+  ++  +    +  PG                   W K+G P+ 
Sbjct: 5243 SSREQEGTESTTDEGQLPQVVEELRDLQVAPGTRLAKFQLKVKGYPAPRLYWFKDGQPLT 5302

Query: 498  ESDRLKVVHKGRIHKLVIANALTEDEGDY------------------VFAPDAYNVTLPA 539
             S  +++  K  +H L I +   ED G Y                  V  PD       +
Sbjct: 5303 ASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARLLVRGPDEPEEKPAS 5362

Query: 540  KVH-VIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSR--GDKAIM---- 592
             VH  + PP++    L+      V  G+ +   + + G P P   W R   ++ ++    
Sbjct: 5363 DVHEQLVPPRM----LERFTPKKVKKGSSITFSVKVEGRPVPTVHWLREEAERGVLWIGP 5418

Query: 593  EGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFP 645
            +  G     S    S +++D+  R   G Y     N AG+A  S  + V   P
Sbjct: 5419 DTPGYTVASSAQQHSLVLLDVG-RQHQGTYTCIASNAAGQALCSASLHVSGLP 5470



 Score = 40.8 bits (94), Expect = 0.007
 Identities = 55/217 (25%), Positives = 88/217 (40%), Gaps = 24/217 (11%)

Query: 734 SRPFVPLAVTSPPTLLTVDSVT----DTTVTMRWRPPDH-IGAAGLDGYVLEYCFEGTED 788
           S  F   A   PP    VD V     +++V + W PP H      +DGY++E    GT  
Sbjct: 500 STQFCVSAPRKPPLQPPVDPVVKARMESSVILSWSPPPHGERPVTIDGYLVEKKKLGTYT 559

Query: 789 WIVANK-DLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIR 847
           WI  ++ + +   + T+  +  +     RV A+N+ G S   Y   P  V      PK+ 
Sbjct: 560 WIRCHEAEWVATPELTVADVAEEGNFQFRVSALNSFGQS--PYLEFPGTVH---LAPKLA 614

Query: 848 IPRHLKQTYIRRVGE---AVNLVIPFQGKPRPELTWKKDGAEIDKNQI-NIRNSETDTII 903
           +   LK       GE   +V+L +   G+      W  DG  +  + +  I    T   +
Sbjct: 615 VRTPLKAVQAVEGGEVTFSVDLTVASAGE------WFLDGQALKASSVYEIHCDRTRHTL 668

Query: 904 FIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPG 940
            IR+   S  G    Q+K       +SI +++   PG
Sbjct: 669 TIREVPASLHG---AQLKFVANGIESSIRMEVRAAPG 702



 Score = 39.7 bits (91), Expect = 0.017
 Identities = 35/138 (25%), Positives = 59/138 (42%), Gaps = 8/138 (5%)

Query: 562  VIAGNKL-RLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSG 620
            V  G +L + ++ + G P P+  W + D   +  S  IR        TL I    R+DSG
Sbjct: 5271 VAPGTRLAKFQLKVKGYPAPRLYWFK-DGQPLTASAHIRMTDKKILHTLEIISVTREDSG 5329

Query: 621  VYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDW----CIMNWEPPAYDGGSPI 676
             Y   + N  G A++S ++ +V  PD P     ++V +       +  + P     GS I
Sbjct: 5330 QYAAYISNAMGAAYSSARL-LVRGPDEPEEKPASDVHEQLVPPRMLERFTPKKVKKGSSI 5388

Query: 677  -LGYFIERKKKQSSRWMR 693
                 +E +   +  W+R
Sbjct: 5389 TFSVKVEGRPVPTVHWLR 5406



 Score = 38.5 bits (88), Expect = 0.037
 Identities = 22/67 (32%), Positives = 34/67 (50%), Gaps = 1/67 (1%)

Query: 1068 GYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSN-QGVCTLEIRKPSPYDGGTYCC 1126
            G +A L+C V G PKP+  W K+   + +  R+ ++ + Q    L+I      D G Y C
Sbjct: 252  GKHARLSCYVTGEPKPETVWKKDGQLVTEGRRHVVYEDAQENFVLKILFCKQSDRGLYTC 311

Query: 1127 KAVNDLG 1133
             A N +G
Sbjct: 312  TASNLVG 318



 Score = 37.0 bits (84), Expect = 0.11
 Identities = 27/86 (31%), Positives = 43/86 (50%), Gaps = 3/86 (3%)

Query: 355  KCSTELFVREPPIMVTKQLEDTTAYCGERVELECEV-SEDDANVKWFKNGEEIIPGPKSR 413
            K   E+  +E P M +    DT A  G+ + LEC V S+ D   +W K+G E+  G +  
Sbjct: 4887 KVRKEMKQQEGP-MFSHTFGDTEAQVGDALRLECVVASKADVRARWLKDGVELTDG-RHH 4944

Query: 414  YRIRVEGKKHILIIEGATKADAAEYS 439
            +  ++      L+I G  +ADA  Y+
Sbjct: 4945 HIDQLGDGTCSLLITGLDRADAGCYT 4970



 Score = 36.6 bits (83), Expect = 0.14
 Identities = 44/206 (21%), Positives = 77/206 (37%), Gaps = 42/206 (20%)

Query: 730 PSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGL------DG-----YV 778
           P   +RP   +        L+   V + T  + W       AAG       DG      +
Sbjct: 10  PRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQDGDLYRLTI 69

Query: 779 LEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVK 838
           L+     +  ++   ++ I +  F   GL  DA+         AA A +  ++       
Sbjct: 70  LDLALGDSGQYVCRARNAIGEA-FAAVGLQVDAE---------AACAEQAPHF------- 112

Query: 839 EIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDG---AEIDKNQINIR 895
            ++ P  IR+    + T+  RVG          G PRP ++W KDG    E D  ++ + 
Sbjct: 113 -LLRPTSIRVREGSEATFRCRVG----------GSPRPAVSWSKDGRRLGEPDGPRVRVE 161

Query: 896 NSETDTIIFIRKAERSHSGKYDLQVK 921
                + + IR A     G Y+++ +
Sbjct: 162 ELGEASALRIRAARPRDGGTYEVRAE 187



 Score = 36.6 bits (83), Expect = 0.14
 Identities = 38/166 (22%), Positives = 61/166 (36%), Gaps = 20/166 (12%)

Query: 999  ITELVIGNEYYFRVFSENMCGLSE-------DATMTK-ESAVIARDGKIY---------- 1040
            IT +V  +   +R  +EN  G+S        D T T  ++A  A +   Y          
Sbjct: 5186 ITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDYDTAADATESSSYFSAQGYLSSR 5245

Query: 1041 -KNPVYEDFDFSEAPMFTQPLVNTYAIAGYN-ATLNCSVRGNPKPKITWMKNKVAIVDDP 1098
             +       D  + P   + L +     G   A     V+G P P++ W K+   +    
Sbjct: 5246 EQEGTESTTDEGQLPQVVEELRDLQVAPGTRLAKFQLKVKGYPAPRLYWFKDGQPLTASA 5305

Query: 1099 RYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVK 1144
              RM   + + TLEI   +  D G Y     N +G      +L V+
Sbjct: 5306 HIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARLLVR 5351



 Score = 35.8 bits (81), Expect = 0.24
 Identities = 21/71 (29%), Positives = 30/71 (42%), Gaps = 2/71 (2%)

Query: 1056 FTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRK 1115
            F   L N  A  G  ATL C +  +    + W K    + D  RY +  +  +C L+IR 
Sbjct: 3276 FIGKLRNKEATEGATATLRCEL--SKAAPVEWRKGSETLRDGDRYCLRQDGAMCELQIRG 3333

Query: 1116 PSPYDGGTYCC 1126
             +  D   Y C
Sbjct: 3334 LAMVDAAEYSC 3344



 Score = 35.8 bits (81), Expect = 0.24
 Identities = 21/71 (29%), Positives = 30/71 (42%), Gaps = 2/71 (2%)

Query: 1056 FTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRK 1115
            F + + N  A  G  A L C +  N    + W K    + D  RY +  +   C L+IR 
Sbjct: 3540 FIEDVKNQEAREGATAVLQCEL--NSAAPVEWRKGSETLRDGDRYSLRQDGTKCELQIRG 3597

Query: 1116 PSPYDGGTYCC 1126
             +  D G Y C
Sbjct: 3598 LAMADTGEYSC 3608



 Score = 35.4 bits (80), Expect = 0.31
 Identities = 21/71 (29%), Positives = 30/71 (42%), Gaps = 2/71 (2%)

Query: 1056 FTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRK 1115
            FT+ L N  A  G  A L C +  +    + W K    + D  R+ +  +   C L+IR 
Sbjct: 3628 FTEGLRNEEATEGATAVLRCEL--SKMAPVEWWKGHETLRDGDRHSLRQDGARCELQIRG 3685

Query: 1116 PSPYDGGTYCC 1126
                D G Y C
Sbjct: 3686 LVAEDAGEYLC 3696



 Score = 34.7 bits (78), Expect = 0.53
 Identities = 20/64 (31%), Positives = 32/64 (50%), Gaps = 1/64 (1%)

Query: 1065 AIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTY 1124
            A AG +ATL+C V    + ++TW K+   +    + RM +      L +++    D G Y
Sbjct: 1546 AEAGTSATLSCEV-AQAQTEVTWYKDGKKLSSSSKVRMEAVGCTRRLVVQEAGQADAGEY 1604

Query: 1125 CCKA 1128
             CKA
Sbjct: 1605 SCKA 1608



 Score = 34.3 bits (77), Expect = 0.70
 Identities = 18/62 (29%), Positives = 30/62 (48%), Gaps = 2/62 (3%)

Query: 1065 AIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTY 1124
            +I G  ATL C +  +    + W K + ++ D  R+ +  +  VC L+I   +  D G Y
Sbjct: 3373 SIEGATATLRCEL--SKAAPVEWRKGRESLRDGDRHSLRQDGAVCELQICGLAVADAGEY 3430

Query: 1125 CC 1126
             C
Sbjct: 3431 SC 3432



 Score = 34.3 bits (77), Expect = 0.70
 Identities = 21/71 (29%), Positives = 31/71 (43%), Gaps = 2/71 (2%)

Query: 1056 FTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRK 1115
            F + L N  A  G  ATL C +  +    + W K    + D  R+ +  +   C L+IR 
Sbjct: 3716 FIEGLRNEEATEGDTATLWCEL--SKAAPVEWRKGHETLRDGDRHSLRQDGSRCELQIRG 3773

Query: 1116 PSPYDGGTYCC 1126
             +  D G Y C
Sbjct: 3774 LAVVDAGEYSC 3784



 Score = 34.3 bits (77), Expect = 0.70
 Identities = 17/59 (28%), Positives = 29/59 (49%), Gaps = 2/59 (3%)

Query: 860  VGEAVNLVIPFQGKPRPELTWKKDG--AEIDKNQINIRNSETDTIIFIRKAERSHSGKY 916
            +GE V L     G P+P ++W KDG   ++D + I I + +    + +       SG+Y
Sbjct: 6027 LGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCALILDSLTGVDSGQY 6085



 Score = 33.5 bits (75), Expect = 1.2
 Identities = 20/83 (24%), Positives = 36/83 (43%), Gaps = 1/83 (1%)

Query: 1055 MFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIR 1114
            + T+PL         +  L+C  R  PK  + W K+   +    +++M     +  L I 
Sbjct: 2470 VLTRPLEPKTGRELQSVVLSCDFRPAPKA-VQWYKDDTPLSPSEKFKMSLEGQMAELRIL 2528

Query: 1115 KPSPYDGGTYCCKAVNDLGTVEI 1137
            +  P D G Y C+A +   + E+
Sbjct: 2529 RLMPADAGVYRCQAGSAHSSTEV 2551



 Score = 33.5 bits (75), Expect = 1.2
 Identities = 20/80 (25%), Positives = 34/80 (42%), Gaps = 1/80 (1%)

Query: 1058 QPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPS 1117
            +PL + +   G +  L C +     P + W+K++ AI    +Y +     +  L IR  S
Sbjct: 2831 KPLEDQWVAPGEDVELRCELSRAGTP-VHWLKDRKAIRKSQKYDVVCEGTMAMLVIRGAS 2889

Query: 1118 PYDGGTYCCKAVNDLGTVEI 1137
              D G Y C+      T  +
Sbjct: 2890 LKDAGEYTCEVEASKSTASL 2909



 Score = 33.1 bits (74), Expect = 1.6
 Identities = 19/64 (29%), Positives = 30/64 (46%), Gaps = 1/64 (1%)

Query: 1065 AIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTY 1124
            A AG  A L+C V   P+ ++TW K+   +    + RM        L +++    D G Y
Sbjct: 1178 AEAGTTAMLSCEV-AQPQTEVTWYKDGKKLSSSSKVRMEVKGCTRRLVVQQVGKADAGEY 1236

Query: 1125 CCKA 1128
             C+A
Sbjct: 1237 SCEA 1240



 Score = 32.7 bits (73), Expect = 2.0
 Identities = 19/71 (26%), Positives = 30/71 (42%), Gaps = 5/71 (7%)

Query: 1073 LNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDL 1132
            L C V  +P+  + W K+ V +    +Y      G   L +   SP D G Y C     +
Sbjct: 2666 LQCEV-SDPEAHVVWRKDGVQLGPSDKYDFLHTAGTRGLVVHDVSPEDAGLYTC----HV 2720

Query: 1133 GTVEIECKLEV 1143
            G+ E   ++ V
Sbjct: 2721 GSEETRARVRV 2731



 Score = 32.3 bits (72), Expect = 2.7
 Identities = 20/92 (21%), Positives = 45/92 (48%), Gaps = 3/92 (3%)

Query: 861 GEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINI--RNSETDTIIFIRKAERSHSGKYDL 918
           G+   L     G+P+PE  WKKDG  + + + ++   +++ + ++ I   ++S  G Y  
Sbjct: 252 GKHARLSCYVTGEPKPETVWKKDGQLVTEGRRHVVYEDAQENFVLKILFCKQSDRGLYTC 311

Query: 919 QVKVDKFVETASIDIQIIDRPGPPQIVKIEDV 950
               +   +T S  + ++  P  P   +++D+
Sbjct: 312 TAS-NLVGQTYSSVLVVVREPAVPFKKRLQDL 342



 Score = 32.3 bits (72), Expect = 2.7
 Identities = 18/61 (29%), Positives = 29/61 (47%)

Query: 288  QVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEY 347
            QV  G  V   +E+     EV W+K  + I+P  ++    +G Q++L I      D  EY
Sbjct: 4634 QVAAGEDVSLELEVVAEAGEVIWHKGMERIQPGGRFEVVSQGRQQMLVIKGFTAEDQGEY 4693

Query: 348  Y 348
            +
Sbjct: 4694 H 4694



 Score = 32.0 bits (71), Expect = 3.5
 Identities = 22/82 (26%), Positives = 39/82 (47%), Gaps = 2/82 (2%)

Query: 1065 AIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTY 1124
            A AG +ATL+C V    + ++TW K+   +    +  M +      L +++    D G Y
Sbjct: 902  AEAGASATLSCEV-AQAQTEVTWYKDGKKLSSSSKVCMEATGCTRRLVVQQAGQADAGEY 960

Query: 1125 CCKAVNDLGTVEIECKLEVKVI 1146
             C+A     +  ++ K E KV+
Sbjct: 961  SCEAGGQRLSFHLDVK-EPKVV 981



 Score = 32.0 bits (71), Expect = 3.5
 Identities = 17/62 (27%), Positives = 32/62 (51%), Gaps = 1/62 (1%)

Query: 1067 AGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCC 1126
            AG +ATL+C V    + ++TW K+   +    + R+ +   +  L +++    D G Y C
Sbjct: 1272 AGASATLSCEV-AQAQTEVTWYKDGKKLSSSSKVRIEAAGCMRQLVVQQAGQADAGEYTC 1330

Query: 1127 KA 1128
            +A
Sbjct: 1331 EA 1332



 Score = 31.6 bits (70), Expect = 4.5
 Identities = 18/64 (28%), Positives = 32/64 (50%), Gaps = 1/64 (1%)

Query: 1065 AIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTY 1124
            A AG +ATL+C V    + ++TW K+   +    + R+ +      L +++    D G Y
Sbjct: 1638 AEAGASATLSCEV-AQAQTEVTWYKDGKKLSSSSKVRVEAVGCTRRLVVQQAGQADAGEY 1696

Query: 1125 CCKA 1128
             C+A
Sbjct: 1697 SCEA 1700



 Score = 31.6 bits (70), Expect = 4.5
 Identities = 21/71 (29%), Positives = 30/71 (42%), Gaps = 2/71 (2%)

Query: 1056 FTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRK 1115
            FT+ L N  A+ G  A L C +  +    + W K    + D  RY +      C L+I  
Sbjct: 3452 FTEGLRNEEAVEGATAMLWCEL--SKVAPVEWRKGPENLRDGDRYILRQEGTRCELQICG 3509

Query: 1116 PSPYDGGTYCC 1126
             +  D G Y C
Sbjct: 3510 LAMADAGEYLC 3520



 Score = 30.8 bits (68), Expect = 7.7
 Identities = 19/77 (24%), Positives = 36/77 (46%)

Query: 565  GNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHI 624
            G+ LRLE  ++ +   +A W +    + +G      +    + +L+I   +R D+G Y  
Sbjct: 4912 GDALRLECVVASKADVRARWLKDGVELTDGRHHHIDQLGDGTCSLLITGLDRADAGCYTC 4971

Query: 625  NLKNEAGEAHASIKVKV 641
             + N+ G+   S  V V
Sbjct: 4972 QVSNKFGQVTHSACVVV 4988


>gi|148833506 obscurin, cytoskeletal calmodulin and titin-interacting
            RhoGEF isoform b [Homo sapiens]
          Length = 7968

 Score =  129 bits (323), Expect = 2e-29
 Identities = 100/370 (27%), Positives = 164/370 (44%), Gaps = 19/370 (5%)

Query: 275  KSAAFAKILDPAYQVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRIL 334
            K   F K LD     ++ G +    E++DP+  V W K+G ++ PS KY F H    R L
Sbjct: 2645 KPVVFLKALDDL-SAEERGTLALQCEVSDPEAHVVWRKDGVQLGPSDKYDFLHTAGTRGL 2703

Query: 335  FINNCQMTDDSEYYVTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDD 394
             +++    D   Y    G E+    + V +  + +TK+L+      GE    EC +S + 
Sbjct: 2704 VVHDVSPEDAGLYTCHVGSEETRARVRVHDLHVGITKRLKTMEVLEGESCSFECVLSHES 2763

Query: 395  AN--VKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLS 452
            A+    W   G+ +  G  SR++   +G+K+IL++  A  +DA E      G  S A L 
Sbjct: 2764 ASDPAMWTVGGKTV--GSSSRFQATRQGRKYILVVREAAPSDAGEVVFSVRGLTSKASLI 2821

Query: 453  VDLKPLKILTPLTDQTVNLGKEICLKCEISE-NIPGKWTKNGLPVQESDRLKVVHKGRIH 511
            V  +P  I+ PL DQ V  G+++ L+CE+S    P  W K+   +++S +  VV +G + 
Sbjct: 2822 VRERPAAIIKPLEDQWVAPGEDVELRCELSRAGTPVHWLKDRKAIRKSQKYDVVCEGTMA 2881

Query: 512  KLVIANALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKII---LDGLDADNTVTVIAGNKL 568
             LVI  A  +D G+Y    +A   T  A +HV +        L  L  +   T +   K 
Sbjct: 2882 MLVIRGASLKDAGEYTCEVEASKST--ASLHVEEKANCFTEELTNLQVEEKGTAVFTCK- 2938

Query: 569  RLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKN 628
                  +  P     W +G    +  SG+ +      +  L I   E+ DS  Y  ++  
Sbjct: 2939 ------TEHPAATVTWRKG-LLELRASGKHQPSQEGLTLRLTISALEKADSDTYTCDIGQ 2991

Query: 629  EAGEAHASIK 638
                A   ++
Sbjct: 2992 AQSRAQLLVQ 3001



 Score =  127 bits (318), Expect = 8e-29
 Identities = 99/387 (25%), Positives = 168/387 (43%), Gaps = 24/387 (6%)

Query: 268  RMRREEKKSAAFAK--ILDPAYQVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIF 325
            R+R  E K   FAK  +     Q + G       E+A  + EV WYK+G+++  S+K   
Sbjct: 880  RLRVSEPK-VVFAKEQLARRKLQAEAGASATLSCEVAQAQTEVTWYKDGKKLSSSSKVCM 938

Query: 326  EHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTELFVREPPIMVTKQL---EDTTAYCGE 382
            E  GC R L +      D  EY   AG ++ S  L V+EP ++  K      +  A  G 
Sbjct: 939  EATGCTRRLVVQQAGQADAGEYSCEAGGQRLSFHLDVKEPKVVFAKDQVAHSEVQAEAGA 998

Query: 383  RVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGK--KHILIIEGATKADAAEYSV 440
               L CEV++    V W+K+G+++     S  ++ VE K  +  L+++ A K DA +YS 
Sbjct: 999  SATLSCEVAQAQTEVMWYKDGKKL----SSSLKVHVEAKGCRRRLVVQQAGKTDAGDYSC 1054

Query: 441  MTTGGQSSAKLSVDLKPL---KILTPLTDQTVNLGKEICLKCEISE-NIPGKWTKNGLPV 496
               G + S +L +    +   K  +   +     G    L CE+++      W K+G  +
Sbjct: 1055 EARGQRVSFRLHITEPKMMFAKEQSVHNEVQAEAGASAMLSCEVAQAQTEVTWYKDGKKL 1114

Query: 497  QESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKIILDGLDA 556
              S ++ +  KG   +LV+  A   D G+Y        V+    +H+ +P  +       
Sbjct: 1115 SSSSKVGMEVKGCTRRLVLPQAGKADAGEYSCEAGGQRVSF--HLHITEPKGVFAKEQSV 1172

Query: 557  DNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAER 616
             N V   AG    L   ++ +P  +  W +  K  +  S ++R E    +  LV+    +
Sbjct: 1173 HNEVQAEAGTTAMLSCEVA-QPQTEVTWYKDGKK-LSSSSKVRMEVKGCTRRLVVQQVGK 1230

Query: 617  DDSGVYHINLKNEAGEAHASIKVKVVD 643
             D+G Y      EAG    S ++ + +
Sbjct: 1231 ADAGEYSC----EAGGQRVSFQLHITE 1253



 Score =  122 bits (306), Expect = 2e-27
 Identities = 100/403 (24%), Positives = 175/403 (43%), Gaps = 31/403 (7%)

Query: 248  EKIAFQYGITDLRGMLKRLKRMRREEKKSAAFAKILDPAYQVDKGGRVRFVVELADPKLE 307
            ++++F   IT+ +G+  + + +  E               Q + G       E+A P+ E
Sbjct: 1151 QRVSFHLHITEPKGVFAKEQSVHNE--------------VQAEAGTTAMLSCEVAQPQTE 1196

Query: 308  VKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTELFVREPPI 367
            V WYK+G+++  S+K   E KGC R L +      D  EY   AG ++ S +L + EP  
Sbjct: 1197 VTWYKDGKKLSSSSKVRMEVKGCTRRLVVQQVGKADAGEYSCEAGGQRVSFQLHITEPKA 1256

Query: 368  MVTKQL---EDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHI 424
            +  K+     +     G    L CEV++    V W+K+G+++     S+ RI   G    
Sbjct: 1257 VFAKEQLVHNEVRTEAGASATLSCEVAQAQTEVTWYKDGKKL--SSSSKVRIEAAGCMRQ 1314

Query: 425  LIIEGATKADAAEYSVMTTGGQSSAKLSV-DLKPLKILTPLTDQTV--NLGKEICLKCEI 481
            L+++ A +ADA EY+    G + S  L V + K +     L  + V    G    L CE+
Sbjct: 1315 LVVQQAGQADAGEYTCEAGGQRLSFHLDVSEPKAVFAKEQLAHRKVQAEAGAIATLSCEV 1374

Query: 482  SE-NIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAK 540
            ++      W K+G  +  S ++++   G   +LV+  A   D G+Y  + +A    L   
Sbjct: 1375 AQAQTEVTWYKDGKKLSSSSKVRMEAVGCTRRLVVQQACQADTGEY--SCEAGGQRLSFS 1432

Query: 541  VHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRT 600
            + V +P  +          V   AG    L   ++ +   + MW +  K  +  S ++R 
Sbjct: 1433 LDVAEPKVVFAKEQPVHREVQAQAGASTTLSCEVA-QAQTEVMWYKDGKK-LSFSSKVRM 1490

Query: 601  ESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVD 643
            E+   +  LV+  A +  +G Y      EAG    S  + V +
Sbjct: 1491 EAVGCTRRLVVQQAGQAVAGEYSC----EAGSQRLSFHLHVAE 1529



 Score =  121 bits (304), Expect = 3e-27
 Identities = 197/876 (22%), Positives = 330/876 (37%), Gaps = 104/876 (11%)

Query: 130  KAGKHLQLKETFERHSRVYTFEMQIIKAKDNFAGNYRCEVTYKDKFDSCSFDLEVHESTG 189
            K GK L         +   T  + + +A    AG Y CE   +      SF L+V E   
Sbjct: 925  KDGKKLSSSSKVCMEATGCTRRLVVQQAGQADAGEYSCEAGGQ----RLSFHLDVKE--- 977

Query: 190  TTPNIDIRSAFKRSGEGQEDAGELDFSGLLKRREVKQQEEEPQVDVWELLKN-------A 242
              P +          E Q +AG    S  L     + Q E       + L +       A
Sbjct: 978  --PKVVFAKDQVAHSEVQAEAGA---SATLSCEVAQAQTEVMWYKDGKKLSSSLKVHVEA 1032

Query: 243  KPSEYEKIAFQYGITDL-------RGMLKRLKRMRREEKKSAAFAKILDPAYQVDKGGRV 295
            K      +  Q G TD        RG     +    E K   A  + +    Q + G   
Sbjct: 1033 KGCRRRLVVQQAGKTDAGDYSCEARGQRVSFRLHITEPKMMFAKEQSVHNEVQAEAGASA 1092

Query: 296  RFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEK 355
                E+A  + EV WYK+G+++  S+K   E KGC R L +      D  EY   AG ++
Sbjct: 1093 MLSCEVAQAQTEVTWYKDGKKLSSSSKVGMEVKGCTRRLVLPQAGKADAGEYSCEAGGQR 1152

Query: 356  CSTELFVREPPIMVTKQL---EDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKS 412
             S  L + EP  +  K+     +  A  G    L CEV++    V W+K+G+++     S
Sbjct: 1153 VSFHLHITEPKGVFAKEQSVHNEVQAEAGTTAMLSCEVAQPQTEVTWYKDGKKL--SSSS 1210

Query: 413  RYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSV-DLKPLKILTPLTDQTV-- 469
            + R+ V+G    L+++   KADA EYS    G + S +L + + K +     L    V  
Sbjct: 1211 KVRMEVKGCTRRLVVQQVGKADAGEYSCEAGGQRVSFQLHITEPKAVFAKEQLVHNEVRT 1270

Query: 470  NLGKEICLKCEISE-NIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVF 528
              G    L CE+++      W K+G  +  S ++++   G + +LV+  A   D G+Y  
Sbjct: 1271 EAGASATLSCEVAQAQTEVTWYKDGKKLSSSSKVRIEAAGCMRQLVVQQAGQADAGEYTC 1330

Query: 529  APDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGD 588
              +A    L   + V +P  +      A   V   AG    L   ++        +  G 
Sbjct: 1331 --EAGGQRLSFHLDVSEPKAVFAKEQLAHRKVQAEAGAIATLSCEVAQAQTEVTWYKDGK 1388

Query: 589  KAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPP 648
            K  +  S ++R E+   +  LV+  A + D+G Y      EAG    S  + V +     
Sbjct: 1389 K--LSSSSKVRMEAVGCTRRLVVQQACQADTGEYSC----EAGGQRLSFSLDVAE----- 1437

Query: 649  VAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKK 708
              P V    +    ++ E  A  G S  L   + + + +   W +      K+ +F  K 
Sbjct: 1438 --PKVVFAKEQ--PVHREVQAQAGASTTLSCEVAQAQTE-VMWYKDG----KKLSFSSKV 1488

Query: 709  MIEGVAYEVRIFAVNA-----------IGISKPSMPSRPFVPLAV--TSPPTLLTVDSVT 755
             +E V    R+    A            G  + S       P AV     P    V +  
Sbjct: 1489 RMEAVGCTRRLVVQQAGQAVAGEYSCEAGSQRLSFHLHVAEPKAVFAKEQPASREVQAEA 1548

Query: 756  DTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTE-DWIVANKDLIDKTKFTITGLPTDAKIF 814
             T+ T+                  E     TE  W    K L   +K  +  +    ++ 
Sbjct: 1549 GTSATLS----------------CEVAQAQTEVTWYKDGKKLSSSSKVRMEAVGCTRRLV 1592

Query: 815  VRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRV----GEAVNLVIPF 870
            V+      AG    K   Q +     +  PK+   +  +Q   R V    G +  L    
Sbjct: 1593 VQEAGQADAGEYSCKAGDQRLSFHLHVAEPKVVFAK--EQPAHREVQAEAGASATLSCEV 1650

Query: 871  QGKPRPELTWKKDGAEI-DKNQINIRNSETDTIIFIRKAERSHSGKYDLQV---KVDKFV 926
              + + E+TW KDG ++   +++ +        + +++A ++ +G+Y  +    ++   +
Sbjct: 1651 -AQAQTEVTWYKDGKKLSSSSKVRVEAVGCTRRLVVQQAGQADAGEYSCEAGGQRLSFRL 1709

Query: 927  ETASIDIQIIDRP--GPPQIVKIEDVWGENVALTWT 960
              A ++ QI +RP    P +VK      E++ LT T
Sbjct: 1710 HVAELEPQISERPCRREPLVVKEH----EDIILTAT 1741



 Score =  108 bits (270), Expect = 3e-23
 Identities = 88/353 (24%), Positives = 153/353 (43%), Gaps = 14/353 (3%)

Query: 290  DKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYV 349
            ++GG   F   ++   + V W+++G  ++PS K+     G    L I++  + D  +  V
Sbjct: 1911 EEGGEATFQCVVSPSDVAVVWFRDGALLQPSEKFAISQSGASHSLTISDLVLEDAGQITV 1970

Query: 350  TAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPG 409
             A     S  L VRE P++  K+LE  T      V LE E++     ++W +N   + PG
Sbjct: 1971 EAEGASSSAALRVREAPVLFKKKLEPQTVEERSSVTLEVELTRPWPELRWTRNATALAPG 2030

Query: 410  PKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTV 469
                  I  EG +H L++     AD   +   T   ++ AKL+V+++ ++++  L     
Sbjct: 2031 --KNVEIHAEGARHRLVLHNVGFADRGFFGCETPDDKTQAKLTVEMRQVRLVRGLQAVEA 2088

Query: 470  NLGKEICLKCEISE-NIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVF 528
                   ++ ++S  ++ G WT++GL  Q+     +  +G +H L ++    ED G  VF
Sbjct: 2089 REQGTATMEVQLSHADVDGSWTRDGLRFQQGPTCHLAVRGPMHTLTLSGLRPEDSGLMVF 2148

Query: 529  APDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGD 588
               A  V   A++ V + P      L     V      K+ LE  +S  P     W + D
Sbjct: 2149 --KAEGVHTSARLVVTELPVSFSRPL---QDVVTTEKEKVTLECELS-RPNVDVRWLK-D 2201

Query: 589  KAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKV 641
               +     +   +     +L I   E  D GVY      +A +A +S  VKV
Sbjct: 2202 GVELRAGKTMAIAAQGACRSLTIYRCEFADQGVYVC----DAHDAQSSASVKV 2250



 Score =  107 bits (268), Expect = 5e-23
 Identities = 74/265 (27%), Positives = 120/265 (45%), Gaps = 10/265 (3%)

Query: 288  QVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEY 347
            Q + G       E+A  + EV WYK+G+++  S+K   E  GC R L +      D  EY
Sbjct: 1545 QAEAGTSATLSCEVAQAQTEVTWYKDGKKLSSSSKVRMEAVGCTRRLVVQEAGQADAGEY 1604

Query: 348  YVTAGDEKCSTELFVREPPIMVTKQL---EDTTAYCGERVELECEVSEDDANVKWFKNGE 404
               AGD++ S  L V EP ++  K+     +  A  G    L CEV++    V W+K+G+
Sbjct: 1605 SCKAGDQRLSFHLHVAEPKVVFAKEQPAHREVQAEAGASATLSCEVAQAQTEVTWYKDGK 1664

Query: 405  EIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSV-DLKPLKILTP 463
            ++     S+ R+   G    L+++ A +ADA EYS    G + S +L V +L+P     P
Sbjct: 1665 KL--SSSSKVRVEAVGCTRRLVVQQAGQADAGEYSCEAGGQRLSFRLHVAELEPQISERP 1722

Query: 464  LTDQ--TVNLGKEICLKCEISENIPG--KWTKNGLPVQESDRLKVVHKGRIHKLVIANAL 519
               +   V   ++I L   ++        W K+G+ ++ S R +   +G  H L +  A 
Sbjct: 1723 CRREPLVVKEHEDIILTATLATPSAATVTWLKDGVEIRRSKRHETASQGDTHTLTVHGAQ 1782

Query: 520  TEDEGDYVFAPDAYNVTLPAKVHVI 544
              D   Y     A     P +V  +
Sbjct: 1783 VLDSAIYSCRVGAEGQDFPVQVEEV 1807



 Score =  106 bits (265), Expect = 1e-22
 Identities = 88/339 (25%), Positives = 149/339 (43%), Gaps = 14/339 (4%)

Query: 308  VKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTELFVREPPI 367
            V+W+K  + +R   ++     G +  L I      D  EY    G E+ S  L VR  P 
Sbjct: 3655 VEWWKGHETLRDGDRHSLRQDGARCELQIRGLVAEDAGEYLCMCGKERTSAMLTVRAMPS 3714

Query: 368  MVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILII 427
               + L +  A  G+   L CE+S+  A V+W K  E +  G   R+ +R +G +  L I
Sbjct: 3715 KFIEGLRNEEATEGDTATLWCELSKA-APVEWRKGHETLRDG--DRHSLRQDGSRCELQI 3771

Query: 428  EGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCEISENIPG 487
             G    DA EYS +    ++SA L+V   P + +  + +Q    G    L+CE+S+  P 
Sbjct: 3772 RGLAVVDAGEYSCVCGQERTSATLTVRALPARFIEDVKNQEAREGATAVLQCELSKAAPV 3831

Query: 488  KWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDY--VFAPDAYNVTLPAKVHVID 545
            +W K    ++  DR  +   G   +L I      D G+Y  V   +  + TL  +     
Sbjct: 3832 EWRKGSETLRGGDRYSLRQDGTRCELQIHGLSVADTGEYSCVCGQERTSATLTVRA---- 3887

Query: 546  PPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPD 605
            P  +  + L    ++    G+   L+  +S EP    +WS+G    ++ +GR        
Sbjct: 3888 PQPVFREPL---QSLQAEEGSTATLQCELS-EPTATVVWSKGGLQ-LQANGRREPRLQGC 3942

Query: 606  SSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDF 644
            ++ LV+   +R+D+G Y     ++A  A  ++    V F
Sbjct: 3943 TAELVLQDLQREDTGEYTCTCGSQATSATLTVTAAPVRF 3981



 Score =  106 bits (264), Expect = 1e-22
 Identities = 78/287 (27%), Positives = 128/287 (44%), Gaps = 10/287 (3%)

Query: 308  VKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTELFVREPPI 367
            V+W K  + +R   +YI   +G +  L I    M D  EY    G E+ S  L +R  P 
Sbjct: 3479 VEWRKGPENLRDGDRYILRQEGTRCELQICGLAMADAGEYLCVCGQERTSATLTIRALPA 3538

Query: 368  MVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILII 427
               + +++  A  G    L+CE++   A V+W K  E +  G   RY +R +G K  L I
Sbjct: 3539 RFIEDVKNQEAREGATAVLQCELNSA-APVEWRKGSETLRDG--DRYSLRQDGTKCELQI 3595

Query: 428  EGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCEISENIPG 487
             G   AD  EYS +    ++SA L+V   P+K    L ++    G    L+CE+S+  P 
Sbjct: 3596 RGLAMADTGEYSCVCGQERTSAMLTVRALPIKFTEGLRNEEATEGATAVLRCELSKMAPV 3655

Query: 488  KWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAKVHVIDPP 547
            +W K    +++ DR  +   G   +L I   + ED G+Y+        +    V  +  P
Sbjct: 3656 EWWKGHETLRDGDRHSLRQDGARCELQIRGLVAEDAGEYLCMCGKERTSAMLTVRAM--P 3713

Query: 548  KIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEG 594
               ++GL  +       G+   L   +S   P +  W +G + + +G
Sbjct: 3714 SKFIEGLRNEEAT---EGDTATLWCELSKAAPVE--WRKGHETLRDG 3755



 Score =  105 bits (263), Expect = 2e-22
 Identities = 95/351 (27%), Positives = 155/351 (44%), Gaps = 14/351 (3%)

Query: 293  GRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAG 352
            G   F  EL+    EV+W  NG  +   + +   HKG +  L + + Q  D      ++ 
Sbjct: 2573 GWASFSCELSHEDEEVEWSLNGMPLYNDSFHEISHKGRRHTLVLKSIQRADAGIVRASSL 2632

Query: 353  DEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKS 412
                S  L VR  P++  K L+D +A     + L+CEVS+ +A+V W K+G ++  GP  
Sbjct: 2633 KVSTSARLEVRVKPVVFLKALDDLSAEERGTLALQCEVSDPEAHVVWRKDGVQL--GPSD 2690

Query: 413  RYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLG 472
            +Y          L++   +  DA  Y+      ++ A++ V    + I   L    V  G
Sbjct: 2691 KYDFLHTAGTRGLVVHDVSPEDAGLYTCHVGSEETRARVRVHDLHVGITKRLKTMEVLEG 2750

Query: 473  KEICLKCEISE---NIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFA 529
            +    +C +S    + P  WT  G  V  S R +   +GR + LV+  A   D G+ VF+
Sbjct: 2751 ESCSFECVLSHESASDPAMWTVGGKTVGSSSRFQATRQGRKYILVVREAAPSDAGEVVFS 2810

Query: 530  PDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDK 589
                 +T  A + V + P  I+  L+ D  V      +LR E+  +G P     W +  K
Sbjct: 2811 --VRGLTSKASLIVRERPAAIIKPLE-DQWVAPGEDVELRCELSRAGTP---VHWLKDRK 2864

Query: 590  AIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVK 640
            AI + S +         + LVI  A   D+G Y   +  EA ++ AS+ V+
Sbjct: 2865 AIRK-SQKYDVVCEGTMAMLVIRGASLKDAGEYTCEV--EASKSTASLHVE 2912



 Score =  105 bits (262), Expect = 2e-22
 Identities = 71/245 (28%), Positives = 111/245 (45%), Gaps = 7/245 (2%)

Query: 290  DKGGRVRFVVELADPK--LEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEY 347
            + G   R   +L+D +    V+W K G E+    KY    +G  R L I+  +  D  EY
Sbjct: 4080 ETGDIARLCCQLSDAESGAVVQWLKEGVELHAGPKYEMRSQGATRELLIHQLEAKDTGEY 4139

Query: 348  YVTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDAN-VKWFKNGEEI 406
                G +K +  L V EP + + + L D      E VE  CEVS   A  V+W   G  +
Sbjct: 4140 ACVTGGQKTAASLRVTEPEVTIVRGLVDAEVTADEDVEFSCEVSRAGATGVQWCLQGLPL 4199

Query: 407  IPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTD 466
                 +   +R +G+ H L ++G T  DA   S       SSA+L+V    + IL PL D
Sbjct: 4200 QSNEVTEVAVR-DGRIHTLRLKGVTPEDAGTVSFHLGNHASSAQLTVRAPEVTILEPLQD 4258

Query: 467  QTVNLGKEICLKCEIS--ENIPGKWTKNGLPVQESDRLKV-VHKGRIHKLVIANALTEDE 523
              ++ G++   +C +S       +W   G+P+Q ++   + V +G +H L +     ED 
Sbjct: 4259 VQLSEGQDASFQCRLSRASGQEARWALGGVPLQANEMNDITVEQGTLHLLTLHKVTLEDA 4318

Query: 524  GDYVF 528
            G   F
Sbjct: 4319 GTVSF 4323



 Score =  105 bits (261), Expect = 3e-22
 Identities = 90/364 (24%), Positives = 150/364 (41%), Gaps = 12/364 (3%)

Query: 288  QVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEY 347
            Q   G       E+A  + EV WYK+G+++  S+K   E  GC R L +         EY
Sbjct: 1453 QAQAGASTTLSCEVAQAQTEVMWYKDGKKLSFSSKVRMEAVGCTRRLVVQQAGQAVAGEY 1512

Query: 348  YVTAGDEKCSTELFVREPPIMVTKQ---LEDTTAYCGERVELECEVSEDDANVKWFKNGE 404
               AG ++ S  L V EP  +  K+     +  A  G    L CEV++    V W+K+G+
Sbjct: 1513 SCEAGSQRLSFHLHVAEPKAVFAKEQPASREVQAEAGTSATLSCEVAQAQTEVTWYKDGK 1572

Query: 405  EIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPL---KIL 461
            ++     S+ R+   G    L+++ A +ADA EYS      + S  L V    +   K  
Sbjct: 1573 KL--SSSSKVRMEAVGCTRRLVVQEAGQADAGEYSCKAGDQRLSFHLHVAEPKVVFAKEQ 1630

Query: 462  TPLTDQTVNLGKEICLKCEISE-NIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALT 520
                +     G    L CE+++      W K+G  +  S +++V   G   +LV+  A  
Sbjct: 1631 PAHREVQAEAGASATLSCEVAQAQTEVTWYKDGKKLSSSSKVRVEAVGCTRRLVVQQAGQ 1690

Query: 521  EDEGDYVFAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPP 580
             D G+Y  + +A    L  ++HV +    I +       + V     + L   ++     
Sbjct: 1691 ADAGEY--SCEAGGQRLSFRLHVAELEPQISERPCRREPLVVKEHEDIILTATLATPSAA 1748

Query: 581  KAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVK 640
               W + D   +  S R  T S  D+ TL +  A+  DS +Y   +  E  +    ++  
Sbjct: 1749 TVTWLK-DGVEIRRSKRHETASQGDTHTLTVHGAQVLDSAIYSCRVGAEGQDFPVQVEEV 1807

Query: 641  VVDF 644
               F
Sbjct: 1808 AAKF 1811



 Score =  105 bits (261), Expect = 3e-22
 Identities = 89/366 (24%), Positives = 152/366 (41%), Gaps = 16/366 (4%)

Query: 288  QVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEY 347
            Q ++G       EL++P   V W K G +++ + +     +GC   L + + Q  D  EY
Sbjct: 3900 QAEEGSTATLQCELSEPTATVVWSKGGLQLQANGRREPRLQGCTAELVLQDLQREDTGEY 3959

Query: 348  YVTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEII 407
              T G +  S  L V   P+   ++L+      G    L CE+S   A+V+W K   ++ 
Sbjct: 3960 TCTCGSQATSATLTVTAAPVRFLRELQHQEVDEGGTAHLCCELSRAGASVEWRKGSLQLF 4019

Query: 408  PGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQ 467
            P  K  Y++  +G    L++ G  + DA +Y+  T   QS A LSV +   K  T L   
Sbjct: 4020 PCAK--YQMVQDGAAAELLVRGVEQEDAGDYTCDTGHTQSMASLSVRVPRPKFKTRLQSL 4077

Query: 468  TVNLGKEICLKCEISENIPG---KWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEG 524
                G    L C++S+   G   +W K G+ +    + ++  +G   +L+I     +D G
Sbjct: 4078 EQETGDIARLCCQLSDAESGAVVQWLKEGVELHAGPKYEMRSQGATRELLIHQLEAKDTG 4137

Query: 525  DYVFAPDAYNVTLPAKVHVIDPPKIILDGL-DADNTVTVIAGNKLRLEIPISGEPPPKAM 583
            +Y            A + V +P   I+ GL DA+    V A   +     +S        
Sbjct: 4138 EYACVTGGQKTA--ASLRVTEPEVTIVRGLVDAE----VTADEDVEFSCEVSRAGATGVQ 4191

Query: 584  WSRGDKAIMEGSGRIRTESYPDS--STLVIDIAERDDSGVYHINLKNEAGEAHASIKVKV 641
            W    + +   S  +   +  D    TL +     +D+G    +L N A  A  +++   
Sbjct: 4192 WCL--QGLPLQSNEVTEVAVRDGRIHTLRLKGVTPEDAGTVSFHLGNHASSAQLTVRAPE 4249

Query: 642  VDFPDP 647
            V   +P
Sbjct: 4250 VTILEP 4255



 Score =  104 bits (259), Expect = 5e-22
 Identities = 89/333 (26%), Positives = 142/333 (42%), Gaps = 10/333 (3%)

Query: 308  VKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTELFVREPPI 367
            V+WYK+   + PS K+    +G    L I      D   Y   AG    STE+ V    +
Sbjct: 2499 VQWYKDDTPLSPSEKFKMSLEGQMAELRILRLMPADAGVYRCQAGSAHSSTEVTVEAREV 2558

Query: 368  MVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILII 427
             VT  L+D  A         CE+S +D  V+W  NG  +     S + I  +G++H L++
Sbjct: 2559 TVTGPLQDAEATEEGWASFSCELSHEDEEVEWSLNGMPLY--NDSFHEISHKGRRHTLVL 2616

Query: 428  EGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCEISE-NIP 486
            +   +ADA      +    +SA+L V +KP+  L  L D +      + L+CE+S+    
Sbjct: 2617 KSIQRADAGIVRASSLKVSTSARLEVRVKPVVFLKALDDLSAEERGTLALQCEVSDPEAH 2676

Query: 487  GKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAKVHVIDP 546
              W K+G+ +  SD+   +H      LV+ +   ED G Y     +      A+V V D 
Sbjct: 2677 VVWRKDGVQLGPSDKYDFLHTAGTRGLVVHDVSPEDAGLYTCHVGSEETR--ARVRVHDL 2734

Query: 547  PKIILDGLDADNTVTVIAGNKLRLEIPISGE-PPPKAMWSRGDKAIMEGSGRIRTESYPD 605
               I   L    T+ V+ G     E  +S E     AMW+ G K +   S R +      
Sbjct: 2735 HVGITKRL---KTMEVLEGESCSFECVLSHESASDPAMWTVGGKTV-GSSSRFQATRQGR 2790

Query: 606  SSTLVIDIAERDDSGVYHINLKNEAGEAHASIK 638
               LV+  A   D+G    +++    +A   ++
Sbjct: 2791 KYILVVREAAPSDAGEVVFSVRGLTSKASLIVR 2823



 Score =  102 bits (253), Expect = 3e-21
 Identities = 86/314 (27%), Positives = 131/314 (41%), Gaps = 13/314 (4%)

Query: 288  QVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEY 347
            +V +GG       L+     VKW      +RP  KY    +G    L + N +  D   Y
Sbjct: 3195 EVLEGGAATLRCVLSSVAAPVKWCYGNNVLRPGDKYSLRQEGAMLELVVRNLRPQDSGRY 3254

Query: 348  YVTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEII 407
              + GD+  S  L V   P     +L +  A  G    L CE+S+  A V+W K  E + 
Sbjct: 3255 SCSFGDQTTSATLTVTALPAQFIGKLRNKEATEGATATLRCELSKA-APVEWRKGSETLR 3313

Query: 408  PGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQ 467
             G   RY +R +G    L I G    DAAEYS +    ++SA L++   P   +  L  Q
Sbjct: 3314 DG--DRYCLRQDGAMCELQIRGLAMVDAAEYSCVCGEERTSASLTIRPMPAHFIGRLRHQ 3371

Query: 468  TVNLGKEICLKCEISENIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDY- 526
                G    L+CE+S+  P +W K    +++ DR  +   G + +L I      D G+Y 
Sbjct: 3372 ESIEGATATLRCELSKAAPVEWRKGRESLRDGDRHSLRQDGAVCELQICGLAVADAGEYS 3431

Query: 527  -VFAPDAYNVTLPAKVHVIDPPKIILDGLDADNTV---TVIAGNKLRLEIPISGEPPPKA 582
             V   +  + TL  K      P    +GL  +  V   T +   +L    P+     P+ 
Sbjct: 3432 CVCGEERTSATLTVKA----LPAKFTEGLRNEEAVEGATAMLWCELSKVAPVEWRKGPEN 3487

Query: 583  MWSRGDKAIMEGSG 596
            +   GD+ I+   G
Sbjct: 3488 L-RDGDRYILRQEG 3500



 Score = 99.8 bits (247), Expect = 1e-20
 Identities = 99/402 (24%), Positives = 162/402 (40%), Gaps = 53/402 (13%)

Query: 278  AFAKILDPAYQVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFIN 337
            +F++ L      +K  +V    EL+ P ++V+W K+G E+R         +G  R L I 
Sbjct: 2167 SFSRPLQDVVTTEKE-KVTLECELSRPNVDVRWLKDGVELRAGKTMAIAAQGACRSLTIY 2225

Query: 338  NCQMTDDSEYYVTAGDEKCST-----------------------------------ELFV 362
             C+  D   Y   A D + S                                    +L V
Sbjct: 2226 RCEFADQGVYVCDAHDAQSSASVKVQGRTYTLIYRRVLAEDAGEIQFVAENAESRAQLRV 2285

Query: 363  REPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKK 422
            +E P+ + + L D  A    R  LEC+VS   A V+WFK  +E+ PGPK  Y +  +G  
Sbjct: 2286 KELPVTLVRPLRDKIAMEKHRGVLECQVSRASAQVRWFKGSQELQPGPK--YELVSDGLY 2343

Query: 423  HILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCE-- 480
              LII      D   Y+      ++SA+  V+ + + I+  L D TV        +CE  
Sbjct: 2344 RKLIISDVHAEDEDTYTCDAGDVKTSAQFFVEEQSITIVRGLQDVTVMEPAPAWFECETS 2403

Query: 481  ISENIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAK 540
            I    P KW      +Q    + +  +G +H+L++    +   G   F       +  A+
Sbjct: 2404 IPSVRPPKWLLGKTVLQAGGNVGLEQEGTVHRLMLRRTCSTMTGPVHFTVGKSRSS--AR 2461

Query: 541  VHVIDPPKIILDGLDADNTVTVIAGNKLR-LEIPISGEPPPKAMWSRGDKAIMEGSGRIR 599
            + V D P ++   L+         G +L+ + +     P PKA+    D   +  S + +
Sbjct: 2462 LVVSDIPVVLTRPLEPK------TGRELQSVVLSCDFRPAPKAVQWYKDDTPLSPSEKFK 2515

Query: 600  TESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKV 641
                   + L I      D+GVY    + +AG AH+S +V V
Sbjct: 2516 MSLEGQMAELRILRLMPADAGVY----RCQAGSAHSSTEVTV 2553



 Score = 96.3 bits (238), Expect = 1e-19
 Identities = 63/220 (28%), Positives = 99/220 (45%), Gaps = 3/220 (1%)

Query: 308  VKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTELFVREPPI 367
            V+W K  + +R   +Y     G +  L I+   + D  EY    G E+ S  L VR P  
Sbjct: 3831 VEWRKGSETLRGGDRYSLRQDGTRCELQIHGLSVADTGEYSCVCGQERTSATLTVRAPQP 3890

Query: 368  MVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILII 427
            +  + L+   A  G    L+CE+SE  A V W K G ++      R   R++G    L++
Sbjct: 3891 VFREPLQSLQAEEGSTATLQCELSEPTATVVWSKGGLQL--QANGRREPRLQGCTAELVL 3948

Query: 428  EGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCEISE-NIP 486
            +   + D  EY+       +SA L+V   P++ L  L  Q V+ G    L CE+S     
Sbjct: 3949 QDLQREDTGEYTCTCGSQATSATLTVTAAPVRFLRELQHQEVDEGGTAHLCCELSRAGAS 4008

Query: 487  GKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDY 526
             +W K  L +    + ++V  G   +L++     ED GDY
Sbjct: 4009 VEWRKGSLQLFPCAKYQMVQDGAAAELLVRGVEQEDAGDY 4048



 Score = 95.1 bits (235), Expect = 3e-19
 Identities = 68/263 (25%), Positives = 113/263 (42%), Gaps = 3/263 (1%)

Query: 264  KRLKRMRREEKKSAAFAKILDPAYQVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKY 323
            +R     R  +K + F++ L  A  + +G  +  V E +   + V W K+G+ +R S + 
Sbjct: 3083 QRASAALRVTEKPSVFSRELTDA-TITEGEDLTLVCETSTCDIPVCWTKDGKTLRGSARC 3141

Query: 324  IFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGER 383
               H+G +  L I    + D   Y   AG    S+ + V   P+   + L+D     G  
Sbjct: 3142 QLSHEGHRAQLLITGATLQDSGRYKCEAGGACSSSIVRVHARPVRFQEALKDLEVLEGGA 3201

Query: 384  VELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTT 443
              L C +S   A VKW      + PG K  Y +R EG    L++      D+  YS    
Sbjct: 3202 ATLRCVLSSVAAPVKWCYGNNVLRPGDK--YSLRQEGAMLELVVRNLRPQDSGRYSCSFG 3259

Query: 444  GGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCEISENIPGKWTKNGLPVQESDRLK 503
               +SA L+V   P + +  L ++    G    L+CE+S+  P +W K    +++ DR  
Sbjct: 3260 DQTTSATLTVTALPAQFIGKLRNKEATEGATATLRCELSKAAPVEWRKGSETLRDGDRYC 3319

Query: 504  VVHKGRIHKLVIANALTEDEGDY 526
            +   G + +L I      D  +Y
Sbjct: 3320 LRQDGAMCELQIRGLAMVDAAEY 3342



 Score = 94.7 bits (234), Expect = 4e-19
 Identities = 70/254 (27%), Positives = 110/254 (43%), Gaps = 5/254 (1%)

Query: 273  EKKSAAFAKILDPAYQVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQR 332
            E+ +A F ++L+P    + GG V    EL+    EV W     ++R   ++    +G  R
Sbjct: 1805 EEVAAKFCRLLEPVCG-ELGGTVTLACELSPACAEVVWRCGNTQLRVGKRFQMVAEGPVR 1863

Query: 333  ILFINNCQMTDDSEYYVTAGDEKCSTELFVREPPIM-VTKQLEDTTAYCGERVELECEVS 391
             L +   +  D  EY   + D+  S +L V  P ++     L    A  G     +C VS
Sbjct: 1864 SLTVLGLRAEDAGEYVCESRDDHTSAQLTVSVPRVVKFMSGLSTVVAEEGGEATFQCVVS 1923

Query: 392  EDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKL 451
              D  V WF++G  + P  K  + I   G  H L I      DA + +V   G  SSA L
Sbjct: 1924 PSDVAVVWFRDGALLQPSEK--FAISQSGASHSLTISDLVLEDAGQITVEAEGASSSAAL 1981

Query: 452  SVDLKPLKILTPLTDQTVNLGKEICLKCEISENIPG-KWTKNGLPVQESDRLKVVHKGRI 510
             V   P+     L  QTV     + L+ E++   P  +WT+N   +     +++  +G  
Sbjct: 1982 RVREAPVLFKKKLEPQTVEERSSVTLEVELTRPWPELRWTRNATALAPGKNVEIHAEGAR 2041

Query: 511  HKLVIANALTEDEG 524
            H+LV+ N    D G
Sbjct: 2042 HRLVLHNVGFADRG 2055



 Score = 94.7 bits (234), Expect = 4e-19
 Identities = 136/633 (21%), Positives = 229/633 (36%), Gaps = 75/633 (11%)

Query: 38   EVSPPSALPPG---LGSRALERKDSDWTLVETPPGEEQAKQNANSQLSILFIEKPQGGTV 94
            E++   A P G   L  R L  KDS     E       A      + S+ F  +    T+
Sbjct: 3049 ELNEIDAQPGGYHVLTLRQLALKDSGTIYFEAGDQRASAALRVTEKPSV-FSRELTDATI 3107

Query: 95   KVGEDITFIAKVKAEDLLRKPTIKWFKGKWMDLASKAGKHLQLKETFERHSRVYTFEMQI 154
              GED+T + +    D+     + W         +K GK L+     +     +  ++ I
Sbjct: 3108 TEGEDLTLVCETSTCDI----PVCW---------TKDGKTLRGSARCQLSHEGHRAQLLI 3154

Query: 155  IKAKDNFAGNYRCEV------------TYKDKFDSCSFDLEVHESTGTTPNIDIRSAFKR 202
              A    +G Y+CE                 +F     DLEV E    T    + S    
Sbjct: 3155 TGATLQDSGRYKCEAGGACSSSIVRVHARPVRFQEALKDLEVLEGGAATLRCVLSSVAAP 3214

Query: 203  SGEGQEDAGELDFSGLLKRREVKQQEEEPQVDVWELLKNAKPSEYEKIAFQYGITDLRGM 262
                     +  +   + R   K    +    +  +++N +P +  + +  +G       
Sbjct: 3215 V--------KWCYGNNVLRPGDKYSLRQEGAMLELVVRNLRPQDSGRYSCSFGDQTTSAT 3266

Query: 263  L-------KRLKRMRREEKKSAAFAKILDPAYQVDKGGRVRFVVELADPKLEVKWYKNGQ 315
            L       + + ++R +E    A A +             R  +  A P   V+W K  +
Sbjct: 3267 LTVTALPAQFIGKLRNKEATEGATATL-------------RCELSKAAP---VEWRKGSE 3310

Query: 316  EIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTELFVREPPIMVTKQLED 375
             +R   +Y     G    L I    M D +EY    G+E+ S  L +R  P     +L  
Sbjct: 3311 TLRDGDRYCLRQDGAMCELQIRGLAMVDAAEYSCVCGEERTSASLTIRPMPAHFIGRLRH 3370

Query: 376  TTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADA 435
              +  G    L CE+S+  A V+W K  E +  G   R+ +R +G    L I G   ADA
Sbjct: 3371 QESIEGATATLRCELSKA-APVEWRKGRESLRDG--DRHSLRQDGAVCELQICGLAVADA 3427

Query: 436  AEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCEISENIPGKWTKNGLP 495
             EYS +    ++SA L+V   P K    L ++    G    L CE+S+  P +W K    
Sbjct: 3428 GEYSCVCGEERTSATLTVKALPAKFTEGLRNEEAVEGATAMLWCELSKVAPVEWRKGPEN 3487

Query: 496  VQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKIILD--G 553
            +++ DR  +  +G   +L I      D G+Y+        +    +  + P + I D   
Sbjct: 3488 LRDGDRYILRQEGTRCELQICGLAMADAGEYLCVCGQERTSATLTIRAL-PARFIEDVKN 3546

Query: 554  LDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDI 613
             +A    T +   +L    P+         W +G + + +G  R           L I  
Sbjct: 3547 QEAREGATAVLQCELNSAAPVE--------WRKGSETLRDGD-RYSLRQDGTKCELQIRG 3597

Query: 614  AERDDSGVYHINLKNEAGEAHASIKVKVVDFPD 646
                D+G Y      E   A  +++   + F +
Sbjct: 3598 LAMADTGEYSCVCGQERTSAMLTVRALPIKFTE 3630



 Score = 93.2 bits (230), Expect = 1e-18
 Identities = 80/337 (23%), Positives = 146/337 (43%), Gaps = 11/337 (3%)

Query: 308  VKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTELFVREPPI 367
            V W K+G EIR S ++    +G    L ++  Q+ D + Y    G E     + V E   
Sbjct: 1750 VTWLKDGVEIRRSKRHETASQGDTHTLTVHGAQVLDSAIYSCRVGAEGQDFPVQVEEVAA 1809

Query: 368  MVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILII 427
               + LE      G  V L CE+S   A V W     ++  G   R+++  EG    L +
Sbjct: 1810 KFCRLLEPVCGELGGTVTLACELSPACAEVVWRCGNTQLRVG--KRFQMVAEGPVRSLTV 1867

Query: 428  EGATKADAAEYSVMTTGGQSSAKLSVDL-KPLKILTPLTDQTVNLGKEICLKCEIS-ENI 485
             G    DA EY   +    +SA+L+V + + +K ++ L+      G E   +C +S  ++
Sbjct: 1868 LGLRAEDAGEYVCESRDDHTSAQLTVSVPRVVKFMSGLSTVVAEEGGEATFQCVVSPSDV 1927

Query: 486  PGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAKVHVID 545
               W ++G  +Q S++  +   G  H L I++ + ED G      +A   +  A + V +
Sbjct: 1928 AVVWFRDGALLQPSEKFAISQSGASHSLTISDLVLEDAGQ--ITVEAEGASSSAALRVRE 1985

Query: 546  PPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPD 605
             P +    L+     TV   + + LE+ ++  P P+  W+R   A+  G   +   +   
Sbjct: 1986 APVLFKKKLEPQ---TVEERSSVTLEVELT-RPWPELRWTRNATALAPGK-NVEIHAEGA 2040

Query: 606  SSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVV 642
               LV+      D G +     ++  +A  +++++ V
Sbjct: 2041 RHRLVLHNVGFADRGFFGCETPDDKTQAKLTVEMRQV 2077



 Score = 90.9 bits (224), Expect = 6e-18
 Identities = 67/274 (24%), Positives = 115/274 (41%), Gaps = 6/274 (2%)

Query: 271  REEKKSAAFAKILDPAYQVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGC 330
            R  +    F K L+P   V++   V   VEL  P  E++W +N   + P        +G 
Sbjct: 1982 RVREAPVLFKKKLEPQ-TVEERSSVTLEVELTRPWPELRWTRNATALAPGKNVEIHAEGA 2040

Query: 331  QRILFINNCQMTDDSEYYVTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEV 390
            +  L ++N    D   +     D+K   +L V    + + + L+   A       +E ++
Sbjct: 2041 RHRLVLHNVGFADRGFFGCETPDDKTQAKLTVEMRQVRLVRGLQAVEAREQGTATMEVQL 2100

Query: 391  SEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAK 450
            S  D +  W ++G     GP     +R  G  H L + G    D+        G  +SA+
Sbjct: 2101 SHADVDGSWTRDGLRFQQGPTCHLAVR--GPMHTLTLSGLRPEDSGLMVFKAEGVHTSAR 2158

Query: 451  LSVDLKPLKILTPLTDQTVNLGKEICLKCEISE-NIPGKWTKNGLPVQESDRLKVVHKGR 509
            L V   P+    PL D      +++ L+CE+S  N+  +W K+G+ ++    + +  +G 
Sbjct: 2159 LVVTELPVSFSRPLQDVVTTEKEKVTLECELSRPNVDVRWLKDGVELRAGKTMAIAAQGA 2218

Query: 510  IHKLVIANALTEDEGDYVFAPDAYNVTLPAKVHV 543
               L I      D+G YV   DA++    A V V
Sbjct: 2219 CRSLTIYRCEFADQGVYVC--DAHDAQSSASVKV 2250



 Score = 90.9 bits (224), Expect = 6e-18
 Identities = 66/241 (27%), Positives = 108/241 (44%), Gaps = 5/241 (2%)

Query: 289  VDKGGRVRFVVELADPKLE-VKWYKNGQEIRPST-KYIFEHKGCQRILFINNCQMTDDSE 346
            V +G    F   ++    E V W+ +   +  +    I    G   +L +    + D   
Sbjct: 3016 VQEGSSATFRCRISPANYEPVHWFLDKTPLHANELNEIDAQPGGYHVLTLRQLALKDSGT 3075

Query: 347  YYVTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEI 406
             Y  AGD++ S  L V E P + +++L D T   GE + L CE S  D  V W K+G+ +
Sbjct: 3076 IYFEAGDQRASAALRVTEKPSVFSRELTDATITEGEDLTLVCETSTCDIPVCWTKDGKTL 3135

Query: 407  IPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTD 466
                 +R ++  EG +  L+I GAT  D+  Y     G  SS+ + V  +P++    L D
Sbjct: 3136 --RGSARCQLSHEGHRAQLLITGATLQDSGRYKCEAGGACSSSIVRVHARPVRFQEALKD 3193

Query: 467  QTVNLGKEICLKCEISE-NIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGD 525
              V  G    L+C +S    P KW      ++  D+  +  +G + +LV+ N   +D G 
Sbjct: 3194 LEVLEGGAATLRCVLSSVAAPVKWCYGNNVLRPGDKYSLRQEGAMLELVVRNLRPQDSGR 3253

Query: 526  Y 526
            Y
Sbjct: 3254 Y 3254



 Score = 88.2 bits (217), Expect = 4e-17
 Identities = 88/374 (23%), Positives = 146/374 (39%), Gaps = 11/374 (2%)

Query: 273  EKKSAAFAKILDPAYQVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQR 332
            E+K+  F + L    QV++ G   F  +   P   V W K   E+R S K+    +G   
Sbjct: 2912 EEKANCFTEELTNL-QVEEKGTAVFTCKTEHPAATVTWRKGLLELRASGKHQPSQEGLTL 2970

Query: 333  ILFINNCQMTDDSEYYVTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSE 392
             L I+  +  D   Y    G  +   +L V+   + + + LED     G      C +S 
Sbjct: 2971 RLTISALEKADSDTYTCDIGQAQSRAQLLVQGRRVHIIEDLEDVDVQEGSSATFRCRISP 3030

Query: 393  DDAN-VKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKL 451
             +   V WF +   +     +    +  G  H+L +      D+          ++SA L
Sbjct: 3031 ANYEPVHWFLDKTPLHANELNEIDAQ-PGGYHVLTLRQLALKDSGTIYFEAGDQRASAAL 3089

Query: 452  SVDLKPLKILTPLTDQTVNLGKEICLKCEISE-NIPGKWTKNGLPVQESDRLKVVHKGRI 510
             V  KP      LTD T+  G+++ L CE S  +IP  WTK+G  ++ S R ++ H+G  
Sbjct: 3090 RVTEKPSVFSRELTDATITEGEDLTLVCETSTCDIPVCWTKDGKTLRGSARCQLSHEGHR 3149

Query: 511  HKLVIANALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRL 570
             +L+I  A  +D G Y         +   +VH   P +      +A   + V+ G    L
Sbjct: 3150 AQLLITGATLQDSGRYKCEAGGACSSSIVRVHA-RPVRF----QEALKDLEVLEGGAATL 3204

Query: 571  EIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEA 630
               +S    P   W  G+  +  G  +           LV+      DSG Y  +  ++ 
Sbjct: 3205 RCVLSSVAAP-VKWCYGNNVLRPGD-KYSLRQEGAMLELVVRNLRPQDSGRYSCSFGDQT 3262

Query: 631  GEAHASIKVKVVDF 644
              A  ++      F
Sbjct: 3263 TSATLTVTALPAQF 3276



 Score = 85.9 bits (211), Expect = 2e-16
 Identities = 87/375 (23%), Positives = 152/375 (40%), Gaps = 17/375 (4%)

Query: 286 AYQVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMT-DD 344
           A Q  +GG V F V+L       +W+ +GQ ++ S+ Y       +  L I     +   
Sbjct: 621 AVQAVEGGEVTFSVDLTVASAG-EWFLDGQALKASSVYEIHCDRTRHTLTIREVPASLHG 679

Query: 345 SEYYVTAGDEKCSTELFVREPPIMVTKQ-----LEDTTAYCGERVELECEVSEDDANVKW 399
           ++    A   + S  + VR  P +   +       +  A   E  +L  E+S+  A V W
Sbjct: 680 AQLKFVANGIESSIRMEVRAAPGLTANKPPAAAAREVLARLHEEAQLLAELSDQAAAVTW 739

Query: 400 FKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLK 459
            K+G  + PGPK  Y ++    + +L++    + DA  Y  ++ GG+ + +LSV      
Sbjct: 740 LKDGRTLSPGPK--YEVQASAGRRVLLVRDVARDDAGLYECVSRGGRIAYQLSVQGLARF 797

Query: 460 ILTPLTDQTVN--LGKEICLKCEISE-NIPGKWTKNGLPVQES-DRLKVVHKGRIHKLVI 515
           +   +    V+   G     +CE SE ++   W K+G+ +  S +R      G  H+LV 
Sbjct: 798 LHKDMAGSCVDAVAGGPAQFECETSEAHVHVHWYKDGMELGHSGERFLQEDVGTRHRLVA 857

Query: 516 ANALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPIS 575
           A    +DEG Y       +V    ++ V +P  +      A   +   AG    L   ++
Sbjct: 858 ATVTRQDEGTYSCRVGEDSVDF--RLRVSEPKVVFAKEQLARRKLQAEAGASATLSCEVA 915

Query: 576 GEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHA 635
                   +  G K  +  S ++  E+   +  LV+  A + D+G Y      +    H 
Sbjct: 916 QAQTEVTWYKDGKK--LSSSSKVCMEATGCTRRLVVQQAGQADAGEYSCEAGGQRLSFHL 973

Query: 636 SIKVKVVDFPDPPVA 650
            +K   V F    VA
Sbjct: 974 DVKEPKVVFAKDQVA 988



 Score = 84.7 bits (208), Expect = 5e-16
 Identities = 88/394 (22%), Positives = 152/394 (38%), Gaps = 36/394 (9%)

Query: 352  GDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDAN-VKWFKNGEEIIPGP 410
            G+   S +L VR P + + + L+D     G+    +C +S       +W   G  +    
Sbjct: 4235 GNHASSAQLTVRAPEVTILEPLQDVQLSEGQDASFQCRLSRASGQEARWALGGVPLQANE 4294

Query: 411  KSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVN 470
             +   +  +G  H+L +   T  DA   S       S A+L V  K   ++  L +    
Sbjct: 4295 MNDITVE-QGTLHLLTLHKVTLEDAGTVSFHVGTCSSEAQLKVTAKNT-VVRGLENVEAL 4352

Query: 471  LGKEICLKCEIS--ENIPGKWTKNGLPVQESDRLKVV--HKGRIHKLVIANALTEDEGDY 526
             G E   +C++S  E     W  +  PV  S+  +VV    G  H L++ N   +D    
Sbjct: 4353 EGGEALFECQLSQPEVAAHTWLLDDEPVHTSENAEVVFFENGLRHLLLLKNLRPQDSCRV 4412

Query: 527  VF-----APDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPIS-GEPPP 580
             F        A+      ++ +++P K             V AG +      +S   P  
Sbjct: 4413 TFLAGDMVTSAFLTVRGWRLEILEPLK----------NAAVRAGAQACFTCTLSEAVPVG 4462

Query: 581  KAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVK 640
            +A W     A+          +      L++  A+   +G      +    +A AS ++ 
Sbjct: 4463 EASWYINGAAVQPDDSDWTVTADGSHHALLLRSAQPHHAGEVTFACR----DAVASARLT 4518

Query: 641  VVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCK 700
            V+  PDPP    V         ++W  P  DGG  + GY +E K+  + +W      LC 
Sbjct: 4519 VLGLPDPPEDAEVVARSSHTVTLSWAAPMSDGGGGLCGYRVEVKEGATGQWR-----LCH 4573

Query: 701  ETTFEPKKMIEGVA----YEVRIFAVNAIGISKP 730
            E    P+ +++G+A    Y  R+ AV  +G  +P
Sbjct: 4574 ELVPGPECVVDGLAPGETYRFRVAAVGPVGAGEP 4607



 Score = 82.0 bits (201), Expect = 3e-15
 Identities = 75/342 (21%), Positives = 139/342 (40%), Gaps = 15/342 (4%)

Query: 296  RFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEK 355
            + + EL+D    V W K+G+ + P  KY  +    +R+L + +    D   Y   +   +
Sbjct: 725  QLLAELSDQAAAVTWLKDGRTLSPGPKYEVQASAGRRVLLVRDVARDDAGLYECVSRGGR 784

Query: 356  CSTELFVREPPIMVTKQLEDT--TAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSR 413
             + +L V+     + K +  +   A  G   + ECE SE   +V W+K+G E +     R
Sbjct: 785  IAYQLSVQGLARFLHKDMAGSCVDAVAGGPAQFECETSEAHVHVHWYKDGME-LGHSGER 843

Query: 414  YRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQT----- 468
            +     G +H L+    T+ D   YS     G+ S    + +   K++            
Sbjct: 844  FLQEDVGTRHRLVAATVTRQDEGTYSCRV--GEDSVDFRLRVSEPKVVFAKEQLARRKLQ 901

Query: 469  VNLGKEICLKCEISE-NIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYV 527
               G    L CE+++      W K+G  +  S ++ +   G   +LV+  A   D G+Y 
Sbjct: 902  AEAGASATLSCEVAQAQTEVTWYKDGKKLSSSSKVCMEATGCTRRLVVQQAGQADAGEY- 960

Query: 528  FAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRG 587
             + +A    L   + V +P  +      A + V   AG    L   ++ +   + MW + 
Sbjct: 961  -SCEAGGQRLSFHLDVKEPKVVFAKDQVAHSEVQAEAGASATLSCEVA-QAQTEVMWYKD 1018

Query: 588  DKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNE 629
             K  +  S ++  E+      LV+  A + D+G Y    + +
Sbjct: 1019 GKK-LSSSLKVHVEAKGCRRRLVVQQAGKTDAGDYSCEARGQ 1059



 Score = 79.0 bits (193), Expect = 2e-14
 Identities = 93/405 (22%), Positives = 153/405 (37%), Gaps = 59/405 (14%)

Query: 291  KGGRVRFVVELADPKLEVK-WYKNGQEIRPS--TKYIFEHKGCQRILFINNCQMTDDSEY 347
            +GG   F  +L+ P++    W  + + +  S   + +F   G + +L + N +  D    
Sbjct: 4353 EGGEALFECQLSQPEVAAHTWLLDDEPVHTSENAEVVFFENGLRHLLLLKNLRPQDSCRV 4412

Query: 348  YVTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSE--DDANVKWFKNGEE 405
               AGD   S  L VR   + + + L++     G +    C +SE        W+ NG  
Sbjct: 4413 TFLAGDMVTSAFLTVRGWRLEILEPLKNAAVRAGAQACFTCTLSEAVPVGEASWYINGAA 4472

Query: 406  IIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSV----DLKPLKIL 461
            + P   S + +  +G  H L++  A    A E +       +SA+L+V    D      +
Sbjct: 4473 VQPDD-SDWTVTADGSHHALLLRSAQPHHAGEVTFACRDAVASARLTVLGLPDPPEDAEV 4531

Query: 462  TPLTDQTVNL---------GKEIC-LKCEISENIPGKW------------TKNGLPVQES 499
               +  TV L         G  +C  + E+ E   G+W              +GL   E+
Sbjct: 4532 VARSSHTVTLSWAAPMSDGGGGLCGYRVEVKEGATGQWRLCHELVPGPECVVDGLAPGET 4591

Query: 500  DRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKIILDGLDADNT 559
             R +V   G +                        V LP  V + +PPK +     A  +
Sbjct: 4592 YRFRVAAVGPVGA-------------------GEPVHLPQTVRLAEPPKPVPPQPSAPES 4632

Query: 560  VTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDS 619
              V AG  + LE+ +  E   + +W +G + I  G GR    S      LVI     +D 
Sbjct: 4633 RQVAAGEDVSLELEVVAE-AGEVIWHKGMERIQPG-GRFEVVSQGRQQMLVIKGFTAEDQ 4690

Query: 620  GVYHINL-KNEAGEAHASIKV-----KVVDFPDPPVAPTVTEVGD 658
            G YH  L +     A A+ +V      V + P P + P   + GD
Sbjct: 4691 GEYHCGLAQGSICPAAATFQVALSPASVDEAPQPSLPPEAAQEGD 4735



 Score = 75.9 bits (185), Expect = 2e-13
 Identities = 76/288 (26%), Positives = 112/288 (38%), Gaps = 25/288 (8%)

Query: 257 TDLRGMLKRLKRMRREEKKSAAFAKILDPAYQVDKGGRVRFVVE----------LADPKL 306
           T    +L  L+R R   +   A      PA     G R   V E            +PK 
Sbjct: 214 TSTAALLAHLQRRREAMRAEGA------PASPPSTGTRTCTVTEGKHARLSCYVTGEPKP 267

Query: 307 EVKWYKNGQEIRPSTKYI-FEHKGCQRILFINNCQMTDDSEYYVTA----GDEKCSTELF 361
           E  W K+GQ +    +++ +E      +L I  C+ +D   Y  TA    G    S  + 
Sbjct: 268 ETVWKKDGQLVTEGRRHVVYEDAQENFVLKILFCKQSDRGLYTCTASNLVGQTYSSVLVV 327

Query: 362 VREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGK 421
           VREP +   K+L+D      E     CEV +      WFK  EE      ++Y I  EG 
Sbjct: 328 VREPAVPFKKRLQDLEVREKESATFLCEVPQPSTEAAWFK--EETRLWASAKYGIEEEGT 385

Query: 422 KHILIIEGATKADAAEYSVMT-TGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCE 480
           +  L +   +  D A Y   T  G ++ A+L+V    L+ L   T   V      C++  
Sbjct: 386 ERRLTVRNVSADDDAVYICETPEGSRTVAELAVQGNLLRKLPRKTAVRVGDTAMFCVELA 445

Query: 481 ISENIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVF 528
           +    P  W +N   V    R+ +  +G  H L I+    ED G   F
Sbjct: 446 VPVG-PVHWLRNQEEVVAGGRVAISAEGTRHTLTISQCCLEDVGQVAF 492



 Score = 67.0 bits (162), Expect = 1e-10
 Identities = 60/217 (27%), Positives = 84/217 (38%), Gaps = 33/217 (15%)

Query: 264 KRLKRMRREEKKSAAFAKILDPAYQVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKY 323
           KRL+ +   EK+SA F                  + E+  P  E  W+K    +  S KY
Sbjct: 337 KRLQDLEVREKESATF------------------LCEVPQPSTEAAWFKEETRLWASAKY 378

Query: 324 IFEHKGCQRILFINNCQMTDDSEYYV-TAGDEKCSTELFV-----REPPIMVTKQLEDTT 377
             E +G +R L + N    DD+ Y   T    +   EL V     R+ P     ++ DT 
Sbjct: 379 GIEEEGTERRLTVRNVSADDDAVYICETPEGSRTVAELAVQGNLLRKLPRKTAVRVGDTA 438

Query: 378 AYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAE 437
            +C   VEL   V      V W +N EE++ G   R  I  EG +H L I      D  +
Sbjct: 439 MFC---VELAVPVGP----VHWLRNQEEVVAG--GRVAISAEGTRHTLTISQCCLEDVGQ 489

Query: 438 YSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKE 474
            + M    Q+S +  V       L P  D  V    E
Sbjct: 490 VAFMAGDCQTSTQFCVSAPRKPPLQPPVDPVVKARME 526



 Score = 64.3 bits (155), Expect = 6e-10
 Identities = 72/308 (23%), Positives = 115/308 (37%), Gaps = 50/308 (16%)

Query: 381 GERVELECE-VSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYS 439
           G+   L C+ V      V W K+ + +  G  +R+R+  +G  + L I      D+ +Y 
Sbjct: 24  GKDATLSCQIVGNPTPQVSWEKDQQPVAAG--ARFRLAQDGDLYRLTILDLALGDSGQYV 81

Query: 440 VMTTGGQSSAKLSVDLK-----------PLKILTPLTDQTVNLGKEICLKCEI--SENIP 486
                    A  +V L+           P  +L P T   V  G E   +C +  S    
Sbjct: 82  CRARNAIGEAFAAVGLQVDAEAACAEQAPHFLLRP-TSIRVREGSEATFRCRVGGSPRPA 140

Query: 487 GKWTKNGLPVQESD--RLKVVHKGRIHKLVIANALTEDEGDY-VFAPDAYNVTLPAKVHV 543
             W+K+G  + E D  R++V   G    L I  A   D G Y V A +       A   V
Sbjct: 141 VSWSKDGRRLGEPDGPRVRVEELGEASALRIRAARPRDGGTYEVRAENPLGAASAAAALV 200

Query: 544 IDPPK------------------------IILDGLDAD------NTVTVIAGNKLRLEIP 573
           +D                           +  +G  A        T TV  G   RL   
Sbjct: 201 VDSDAADTASRPGTSTAALLAHLQRRREAMRAEGAPASPPSTGTRTCTVTEGKHARLSCY 260

Query: 574 ISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEA 633
           ++GEP P+ +W +  + + EG   +  E   ++  L I   ++ D G+Y     N  G+ 
Sbjct: 261 VTGEPKPETVWKKDGQLVTEGRRHVVYEDAQENFVLKILFCKQSDRGLYTCTASNLVGQT 320

Query: 634 HASIKVKV 641
           ++S+ V V
Sbjct: 321 YSSVLVVV 328



 Score = 63.9 bits (154), Expect = 8e-10
 Identities = 52/197 (26%), Positives = 83/197 (42%), Gaps = 12/197 (6%)

Query: 469 VNLGKEICLKCEISENIPGK--WTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDY 526
           V++GK+  L C+I  N   +  W K+  PV    R ++   G +++L I +    D G Y
Sbjct: 21  VSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQDGDLYRLTILDLALGDSGQY 80

Query: 527 VF-APDAYNVTLPAKVHVIDPPKIILDG----LDADNTVTVIAGNKLRLEIPISGEPPPK 581
           V  A +A      A    +D      +     L    ++ V  G++      + G P P 
Sbjct: 81  VCRARNAIGEAFAAVGLQVDAEAACAEQAPHFLLRPTSIRVREGSEATFRCRVGGSPRPA 140

Query: 582 AMWSRGDKAIMEGSG-RIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVK 640
             WS+  + + E  G R+R E   ++S L I  A   D G Y +  +N  G A A+  + 
Sbjct: 141 VSWSKDGRRLGEPDGPRVRVEELGEASALRIRAARPRDGGTYEVRAENPLGAASAAAALV 200

Query: 641 VVDFPDPPVAPTVTEVG 657
           V    D   A T +  G
Sbjct: 201 V----DSDAADTASRPG 213



 Score = 56.6 bits (135), Expect = 1e-07
 Identities = 50/185 (27%), Positives = 82/185 (44%), Gaps = 12/185 (6%)

Query: 464  LTDQTVNLGKEICLKCEISENIPG--KWTKNGLPVQESDRLKVVHKGRIHKLVIANALTE 521
            L D T  LG+ + L C ++        W K+G  VQ      ++        +I ++LT 
Sbjct: 6020 LADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCALILDSLTG 6079

Query: 522  -DEGDYVF--APDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEP 578
             D G Y+   A  A N +   K+ V  PP+ +    +       + G   +    I G P
Sbjct: 6080 VDSGQYMCFAASAAGNCSTLGKILVQVPPRFV----NKVRASPFVEGEDAQFTCTIEGAP 6135

Query: 579  PPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDI--AERDDSGVYHINLKNEAGEAHAS 636
             P+  W + D A++    + +T S P S  LV+ I  A ++D G+Y   L N  G A AS
Sbjct: 6136 YPQIRWYK-DGALLTTGNKFQTLSEPRSGLLVLVIRAASKEDLGLYECELVNRLGSARAS 6194

Query: 637  IKVKV 641
             ++++
Sbjct: 6195 AELRI 6199



 Score = 56.2 bits (134), Expect = 2e-07
 Identities = 46/178 (25%), Positives = 78/178 (43%), Gaps = 13/178 (7%)

Query: 561  TVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIR-TESYPDSSTLVIDIAERDDS 619
            TV+ G  + L   +S +P  +A WS+ D A +E S R+  + +  +   L I +   +D 
Sbjct: 7473 TVVLGQSVTLACQVSAQPAAQATWSK-DGAPLESSSRVLISATLKNFQLLTILVVVAEDL 7531

Query: 620  GVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGY 679
            GVY  ++ N  G    +  ++  + P     P + EV  D  ++ W+P   +   P+   
Sbjct: 7532 GVYTCSVSNALGTVTTTGVLRKAERPSSSPCPDIGEVYADGVLLVWKP--VESYGPVT-- 7587

Query: 680  FIERKKKQSSRWMRLN---FDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPS 734
            +I +   +   W  L    FD C  T+    K+  G  Y  R   V+  G+   S PS
Sbjct: 7588 YIVQCSLEGGSWTTLASDIFDCCYLTS----KLSRGGTYTFRTACVSKAGMGPYSSPS 7641



 Score = 54.7 bits (130), Expect = 5e-07
 Identities = 60/290 (20%), Positives = 103/290 (35%), Gaps = 29/290 (10%)

Query: 839  EIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEI--DKNQINIRN 896
            EI+EP        LK   +R   +A       +  P  E +W  +GA +  D +   +  
Sbjct: 4433 EILEP--------LKNAAVRAGAQACFTCTLSEAVPVGEASWYINGAAVQPDDSDWTVTA 4484

Query: 897  SETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVA 956
              +   + +R A+  H+G+     +       AS  + ++  P PP+  ++       V 
Sbjct: 4485 DGSHHALLLRSAQPHHAGEVTFACRD----AVASARLTVLGLPDPPEDAEVVARSSHTVT 4540

Query: 957  LTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSEN 1016
            L+W  P  DG   + GY ++  +  + +W    E        +  L  G  Y FRV +  
Sbjct: 4541 LSWAAPMSDGGGGLCGYRVEVKEGATGQWRLCHELVPGPECVVDGLAPGETYRFRVAAVG 4600

Query: 1017 MCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCS 1076
              G  E   + +   +      +   P         AP   Q        AG + +L   
Sbjct: 4601 PVGAGEPVHLPQTVRLAEPPKPVPPQP--------SAPESRQ------VAAGEDVSLELE 4646

Query: 1077 VRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCC 1126
            V      ++ W K    I    R+ + S      L I+  +  D G Y C
Sbjct: 4647 VVAE-AGEVIWHKGMERIQPGGRFEVVSQGRQQMLVIKGFTAEDQGEYHC 4695



 Score = 53.9 bits (128), Expect = 9e-07
 Identities = 31/95 (32%), Positives = 51/95 (53%), Gaps = 2/95 (2%)

Query: 1050 FSEAPMF-TQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGV 1108
            FS AP F T+P     ++ G +ATL+C + GNP P+++W K++  +    R+R+  +  +
Sbjct: 6    FSGAPRFLTRPKAFVVSV-GKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQDGDL 64

Query: 1109 CTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1143
              L I   +  D G Y C+A N +G       L+V
Sbjct: 65   YRLTILDLALGDSGQYVCRARNAIGEAFAAVGLQV 99



 Score = 53.5 bits (127), Expect = 1e-06
 Identities = 117/569 (20%), Positives = 219/569 (38%), Gaps = 75/569 (13%)

Query: 381 GERVELECEVS-EDDANVKWFKNGEEIIPGPKSRYRIRVEGKKH-ILIIEGATKADAAEY 438
           G+   L C V+ E      W K+G+ +  G   R+ +  + +++ +L I    ++D   Y
Sbjct: 252 GKHARLSCYVTGEPKPETVWKKDGQLVTEG--RRHVVYEDAQENFVLKILFCKQSDRGLY 309

Query: 439 SVMTTG--GQSSAKLSVDLKP--LKILTPLTDQTVNLGKEICLKCEISE-NIPGKWTKNG 493
           +   +   GQ+ + + V ++   +     L D  V   +     CE+ + +    W K  
Sbjct: 310 TCTASNLVGQTYSSVLVVVREPAVPFKKRLQDLEVREKESATFLCEVPQPSTEAAWFKEE 369

Query: 494 LPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVF-APDAYNVTLPAKVHVIDPPKIILD 552
             +  S +  +  +G   +L + N   +D+  Y+   P+         V        +L 
Sbjct: 370 TRLWASAKYGIEEEGTERRLTVRNVSADDDAVYICETPEGSRTVAELAVQ-----GNLLR 424

Query: 553 GLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVID 612
            L     V V       +E+ +   P     W R  + ++ G GR+   +     TL I 
Sbjct: 425 KLPRKTAVRVGDTAMFCVELAV---PVGPVHWLRNQEEVVAG-GRVAISAEGTRHTLTIS 480

Query: 613 IAERDDSGVYHINLKNEAGEAHASIKVKVVDFP-----DPPVAPTVTEVGDDWCIMNWEP 667
               +D G     +   AG+   S +   V  P      PPV P V    +   I++W P
Sbjct: 481 QCCLEDVG----QVAFMAGDCQTSTQF-CVSAPRKPPLQPPVDPVVKARMESSVILSWSP 535

Query: 668 PAYDGGSPIL--GYFIERKKKQSSRWMRLNFDLCKETTF--EPKKMIEGVA----YEVRI 719
           P + G  P+   GY +E+KK  +  W+R     C E  +   P+  +  VA    ++ R+
Sbjct: 536 PPH-GERPVTIDGYLVEKKKLGTYTWIR-----CHEAEWVATPELTVADVAEEGNFQFRV 589

Query: 720 FAVNAIGISKPSMPSRPFV----PLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLD 775
            A+N+ G S P +     V     LAV +P  L  V +V    VT               
Sbjct: 590 SALNSFGQS-PYLEFPGTVHLAPKLAVRTP--LKAVQAVEGGEVT--------------- 631

Query: 776 GYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPI 835
            + ++       +W +  + L   + + I    T   + +R    +  GA + K+ +  I
Sbjct: 632 -FSVDLTVASAGEWFLDGQALKASSVYEIHCDRTRHTLTIREVPASLHGA-QLKFVANGI 689

Query: 836 ---LVKEIIEPPKI---RIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDK 889
              +  E+   P +   + P    +  + R+ E   L+     +    +TW KDG  +  
Sbjct: 690 ESSIRMEVRAAPGLTANKPPAAAAREVLARLHEEAQLLAELSDQ-AAAVTWLKDGRTLSP 748

Query: 890 N-QINIRNSETDTIIFIRKAERSHSGKYD 917
             +  ++ S    ++ +R   R  +G Y+
Sbjct: 749 GPKYEVQASAGRRVLLVRDVARDDAGLYE 777



 Score = 53.1 bits (126), Expect = 1e-06
 Identities = 32/94 (34%), Positives = 43/94 (45%), Gaps = 2/94 (2%)

Query: 1052 EAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKN--KVAIVDDPRYRMFSNQGVC 1109
            +AP F     +     G  AT  C V G+P+P ++W K+  ++   D PR R+       
Sbjct: 108  QAPHFLLRPTSIRVREGSEATFRCRVGGSPRPAVSWSKDGRRLGEPDGPRVRVEELGEAS 167

Query: 1110 TLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1143
             L IR   P DGGTY  +A N LG       L V
Sbjct: 168  ALRIRAARPRDGGTYEVRAENPLGAASAAAALVV 201



 Score = 51.6 bits (122), Expect = 4e-06
 Identities = 30/92 (32%), Positives = 42/92 (45%), Gaps = 1/92 (1%)

Query: 1053 APMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSN-QGVCTL 1111
            AP+F   L N     GY  + +C V G P P + W K+   + +D  Y +  + QG   L
Sbjct: 5125 APVFLTELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLLEEDDHYMINEDQQGGHQL 5184

Query: 1112 EIRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1143
             I    P D G Y C A N +G    + +L V
Sbjct: 5185 IITAVVPADMGVYRCLAENSMGVSSTKAELRV 5216



 Score = 50.1 bits (118), Expect = 1e-05
 Identities = 30/93 (32%), Positives = 43/93 (46%), Gaps = 1/93 (1%)

Query: 1054 PMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSN-QGVCTLE 1112
            P F + L +  A  G    L C V G PKP I+W K+  A+  DP + +  +  G C L 
Sbjct: 6014 PDFEEELADCTAELGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCALI 6073

Query: 1113 IRKPSPYDGGTYCCKAVNDLGTVEIECKLEVKV 1145
            +   +  D G Y C A +  G      K+ V+V
Sbjct: 6074 LDSLTGVDSGQYMCFAASAAGNCSTLGKILVQV 6106



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 44/156 (28%), Positives = 67/156 (42%), Gaps = 8/156 (5%)

Query: 729  KPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTED 788
            + ++ S     L +  PP    V + +  TVT+ W  P   G  GL GY +E     T  
Sbjct: 4509 RDAVASARLTVLGLPDPPEDAEVVARSSHTVTLSWAAPMSDGGGGLCGYRVEVKEGATGQ 4568

Query: 789  WIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRI 848
            W + + +L+   +  + GL        RV AV   GA EP +  Q +    + EPPK  +
Sbjct: 4569 WRLCH-ELVPGPECVVDGLAPGETYRFRVAAVGPVGAGEPVHLPQTV---RLAEPPK-PV 4623

Query: 849  PRHLKQTYIRRV--GEAVNLVIPFQGKPRPELTWKK 882
            P        R+V  GE V+L +    +   E+ W K
Sbjct: 4624 PPQPSAPESRQVAAGEDVSLELEVVAE-AGEVIWHK 4658



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 28/100 (28%), Positives = 44/100 (44%), Gaps = 2/100 (2%)

Query: 1047 DFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQ 1106
            D   +  P     + +  A  G  A     + G+P+P +TW K+ V +VD  R       
Sbjct: 6350 DTHTARPPSMQVTIEDVQAQTGGTAQFEAIIEGDPQPSVTWYKDSVQLVDSTRLSQQQEG 6409

Query: 1107 GVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVKVI 1146
               +L +R  +  D G Y C A N  G  ++ CK E+ V+
Sbjct: 6410 TTYSLVLRHVASKDAGVYTCLAQNTGG--QVLCKAELLVL 6447



 Score = 48.9 bits (115), Expect = 3e-05
 Identities = 26/93 (27%), Positives = 44/93 (47%), Gaps = 2/93 (2%)

Query: 1054 PMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFS--NQGVCTL 1111
            P F   +  +  + G +A   C++ G P P+I W K+   +    +++  S    G+  L
Sbjct: 6108 PRFVNKVRASPFVEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSEPRSGLLVL 6167

Query: 1112 EIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVK 1144
             IR  S  D G Y C+ VN LG+     +L ++
Sbjct: 6168 VIRAASKEDLGLYECELVNRLGSARASAELRIQ 6200



 Score = 48.1 bits (113), Expect = 5e-05
 Identities = 72/323 (22%), Positives = 123/323 (38%), Gaps = 63/323 (19%)

Query: 238  LLKNAKPSEYEKIAFQYG--ITDLRGMLKRLKRMRREEKKSAAFAKILDPAYQVDKGGRV 295
            LLKN +P +  ++ F  G  +T     ++  +    E  K+AA          V  G + 
Sbjct: 4400 LLKNLRPQDSCRVTFLAGDMVTSAFLTVRGWRLEILEPLKNAA----------VRAGAQA 4449

Query: 296  RFVVELAD--PKLEVKWYKNGQEIRPS-TKYIFEHKGCQRILFINNCQMTDDSEYYVTAG 352
             F   L++  P  E  WY NG  ++P  + +     G    L + + Q     E      
Sbjct: 4450 CFTCTLSEAVPVGEASWYINGAAVQPDDSDWTVTADGSHHALLLRSAQPHHAGEVTFACR 4509

Query: 353  DEKCSTELFVR---EPPI---MVTKQLEDTT------------AYCGERVELECEVSEDD 394
            D   S  L V    +PP    +V +     T              CG RVE++     + 
Sbjct: 4510 DAVASARLTVLGLPDPPEDAEVVARSSHTVTLSWAAPMSDGGGGLCGYRVEVK-----EG 4564

Query: 395  ANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGG--------- 445
            A  +W +   E++PGP+              +++G    +   + V   G          
Sbjct: 4565 ATGQW-RLCHELVPGPEC-------------VVDGLAPGETYRFRVAAVGPVGAGEPVHL 4610

Query: 446  QSSAKLSVDLKPLKILTPLTD-QTVNLGKEICLKCEI-SENIPGKWTKNGLPVQESDRLK 503
              + +L+   KP+       + + V  G+++ L+ E+ +E     W K    +Q   R +
Sbjct: 4611 PQTVRLAEPPKPVPPQPSAPESRQVAAGEDVSLELEVVAEAGEVIWHKGMERIQPGGRFE 4670

Query: 504  VVHKGRIHKLVIANALTEDEGDY 526
            VV +GR   LVI     ED+G+Y
Sbjct: 4671 VVSQGRQQMLVIKGFTAEDQGEY 4693



 Score = 48.1 bits (113), Expect = 5e-05
 Identities = 37/159 (23%), Positives = 68/159 (42%), Gaps = 7/159 (4%)

Query: 304  PKLEVKWYKNGQEIRPSTKYI-FEHKGCQRILFINNCQMTDDSEY--YVTAGDEKCST-- 358
            PK  + WYK+G+ ++    +I  E       L +++    D  +Y  +  +    CST  
Sbjct: 6041 PKPVISWYKDGKAVQVDPHHILIEDPDGSCALILDSLTGVDSGQYMCFAASAAGNCSTLG 6100

Query: 359  ELFVREPPIMVTKQLEDTTAYCGERVELECEV-SEDDANVKWFKNGEEIIPGPKSRYRIR 417
            ++ V+ PP  V K +  +    GE  +  C +       ++W+K+G  +  G K +    
Sbjct: 6101 KILVQVPPRFVNK-VRASPFVEGEDAQFTCTIEGAPYPQIRWYKDGALLTTGNKFQTLSE 6159

Query: 418  VEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLK 456
                  +L+I  A+K D   Y         SA+ S +L+
Sbjct: 6160 PRSGLLVLVIRAASKEDLGLYECELVNRLGSARASAELR 6198



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 33/114 (28%), Positives = 47/114 (41%), Gaps = 3/114 (2%)

Query: 1023 DATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPK 1082
            D +M K +  I    K YK  V ++    E PMF+    +T A  G    L C V     
Sbjct: 4869 DPSMDKAAVKIQAAFKGYK--VRKEMKQQEGPMFSHTFGDTEAQVGDALRLECVVASKAD 4926

Query: 1083 PKITWMKNKVAIVDDPRYRMFS-NQGVCTLEIRKPSPYDGGTYCCKAVNDLGTV 1135
             +  W+K+ V + D   + +     G C+L I      D G Y C+  N  G V
Sbjct: 4927 VRARWLKDGVELTDGRHHHIDQLGDGTCSLLITGLDRADAGCYTCQVSNKFGQV 4980



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 74/353 (20%), Positives = 126/353 (35%), Gaps = 81/353 (22%)

Query: 366  PIMVTKQLEDTTAYCGERVELECEVS-EDDANVKWFKNGEEIIPGPKSRYRIRVEGKK-H 423
            P+ +T +L++     G  V  +C V+ +   +V+WFK+G+ +       Y I  + +  H
Sbjct: 5126 PVFLT-ELQNQEVQDGYPVSFDCVVTGQPMPSVRWFKDGKLL--EEDDHYMINEDQQGGH 5182

Query: 424  ILIIEGATKADAAEYSVMTTGGQ----SSAKLSVDLKPLKILTPL--------------- 464
             LII     AD   Y  +         + A+L VDL      T                 
Sbjct: 5183 QLIITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDYDTAADATESSSYFSAQGYL 5242

Query: 465  -------TDQTVNLGK--EICLKCEISENIPGK------------------WTKNGLPVQ 497
                   T+ T + G+  ++  +    +  PG                   W K+G P+ 
Sbjct: 5243 SSREQEGTESTTDEGQLPQVVEELRDLQVAPGTRLAKFQLKVKGYPAPRLYWFKDGQPLT 5302

Query: 498  ESDRLKVVHKGRIHKLVIANALTEDEGDY------------------VFAPDAYNVTLPA 539
             S  +++  K  +H L I +   ED G Y                  V  PD       +
Sbjct: 5303 ASAHIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARLLVRGPDEPEEKPAS 5362

Query: 540  KVH-VIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSR--GDKAIM---- 592
             VH  + PP++    L+      V  G+ +   + + G P P   W R   ++ ++    
Sbjct: 5363 DVHEQLVPPRM----LERFTPKKVKKGSSITFSVKVEGRPVPTVHWLREEAERGVLWIGP 5418

Query: 593  EGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFP 645
            +  G     S    S +++D+  R   G Y     N AG+A  S  + V   P
Sbjct: 5419 DTPGYTVASSAQQHSLVLLDVG-RQHQGTYTCIASNAAGQALCSASLHVSGLP 5470



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 36/166 (21%), Positives = 65/166 (39%), Gaps = 12/166 (7%)

Query: 860  VGEAVNLVIPFQGKPRPELTWKKDGAEIDKN-----QINIRNSETDTIIFIRKAERSHSG 914
            +G++V L      +P  + TW KDGA ++ +        ++N +  TI+ +   +    G
Sbjct: 7476 LGQSVTLACQVSAQPAAQATWSKDGAPLESSSRVLISATLKNFQLLTILVVVAED---LG 7532

Query: 915  KYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYT 974
             Y   V       T +  ++  +RP       I +V+ + V L W P +  G      Y 
Sbjct: 7533 VYTCSVSNALGTVTTTGVLRKAERPSSSPCPDIGEVYADGVLLVWKPVESYGPVT---YI 7589

Query: 975  IQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGL 1020
            +Q    +   W T+           ++L  G  Y FR    +  G+
Sbjct: 7590 VQ-CSLEGGSWTTLASDIFDCCYLTSKLSRGGTYTFRTACVSKAGM 7634



 Score = 40.8 bits (94), Expect = 0.007
 Identities = 55/217 (25%), Positives = 88/217 (40%), Gaps = 24/217 (11%)

Query: 734 SRPFVPLAVTSPPTLLTVDSVT----DTTVTMRWRPPDH-IGAAGLDGYVLEYCFEGTED 788
           S  F   A   PP    VD V     +++V + W PP H      +DGY++E    GT  
Sbjct: 500 STQFCVSAPRKPPLQPPVDPVVKARMESSVILSWSPPPHGERPVTIDGYLVEKKKLGTYT 559

Query: 789 WIVANK-DLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIR 847
           WI  ++ + +   + T+  +  +     RV A+N+ G S   Y   P  V      PK+ 
Sbjct: 560 WIRCHEAEWVATPELTVADVAEEGNFQFRVSALNSFGQS--PYLEFPGTVH---LAPKLA 614

Query: 848 IPRHLKQTYIRRVGE---AVNLVIPFQGKPRPELTWKKDGAEIDKNQI-NIRNSETDTII 903
           +   LK       GE   +V+L +   G+      W  DG  +  + +  I    T   +
Sbjct: 615 VRTPLKAVQAVEGGEVTFSVDLTVASAGE------WFLDGQALKASSVYEIHCDRTRHTL 668

Query: 904 FIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPG 940
            IR+   S  G    Q+K       +SI +++   PG
Sbjct: 669 TIREVPASLHG---AQLKFVANGIESSIRMEVRAAPG 702



 Score = 40.4 bits (93), Expect = 0.010
 Identities = 30/110 (27%), Positives = 43/110 (39%), Gaps = 7/110 (6%)

Query: 1033 IARDGKIYKNPVYEDFDFS------EAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKIT 1086
            + ++G   K P    F  S       AP F + L +   + G + TL C V   P  + T
Sbjct: 7436 LEKEGPPRKKPGLASFRLSGLKSWDRAPTFLRELSDETVVLGQSVTLACQVSAQPAAQAT 7495

Query: 1087 WMKNKVAIVDDPRYRMFSN-QGVCTLEIRKPSPYDGGTYCCKAVNDLGTV 1135
            W K+   +    R  + +  +    L I      D G Y C   N LGTV
Sbjct: 7496 WSKDGAPLESSSRVLISATLKNFQLLTILVVVAEDLGVYTCSVSNALGTV 7545



 Score = 39.7 bits (91), Expect = 0.017
 Identities = 35/138 (25%), Positives = 59/138 (42%), Gaps = 8/138 (5%)

Query: 562  VIAGNKL-RLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSG 620
            V  G +L + ++ + G P P+  W + D   +  S  IR        TL I    R+DSG
Sbjct: 5271 VAPGTRLAKFQLKVKGYPAPRLYWFK-DGQPLTASAHIRMTDKKILHTLEIISVTREDSG 5329

Query: 621  VYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDW----CIMNWEPPAYDGGSPI 676
             Y   + N  G A++S ++ +V  PD P     ++V +       +  + P     GS I
Sbjct: 5330 QYAAYISNAMGAAYSSARL-LVRGPDEPEEKPASDVHEQLVPPRMLERFTPKKVKKGSSI 5388

Query: 677  -LGYFIERKKKQSSRWMR 693
                 +E +   +  W+R
Sbjct: 5389 TFSVKVEGRPVPTVHWLR 5406



 Score = 38.5 bits (88), Expect = 0.037
 Identities = 22/67 (32%), Positives = 34/67 (50%), Gaps = 1/67 (1%)

Query: 1068 GYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSN-QGVCTLEIRKPSPYDGGTYCC 1126
            G +A L+C V G PKP+  W K+   + +  R+ ++ + Q    L+I      D G Y C
Sbjct: 252  GKHARLSCYVTGEPKPETVWKKDGQLVTEGRRHVVYEDAQENFVLKILFCKQSDRGLYTC 311

Query: 1127 KAVNDLG 1133
             A N +G
Sbjct: 312  TASNLVG 318



 Score = 37.4 bits (85), Expect = 0.083
 Identities = 22/69 (31%), Positives = 35/69 (50%), Gaps = 3/69 (4%)

Query: 461  LTPLTDQTVNLGKEICLKCEISEN--IPGKWTKNGLPVQESDRLKV-VHKGRIHKLVIAN 517
            L  L+D+TV LG+ + L C++S        W+K+G P++ S R+ +         L I  
Sbjct: 7466 LRELSDETVVLGQSVTLACQVSAQPAAQATWSKDGAPLESSSRVLISATLKNFQLLTILV 7525

Query: 518  ALTEDEGDY 526
             + ED G Y
Sbjct: 7526 VVAEDLGVY 7534



 Score = 37.0 bits (84), Expect = 0.11
 Identities = 27/86 (31%), Positives = 43/86 (50%), Gaps = 3/86 (3%)

Query: 355  KCSTELFVREPPIMVTKQLEDTTAYCGERVELECEV-SEDDANVKWFKNGEEIIPGPKSR 413
            K   E+  +E P M +    DT A  G+ + LEC V S+ D   +W K+G E+  G +  
Sbjct: 4887 KVRKEMKQQEGP-MFSHTFGDTEAQVGDALRLECVVASKADVRARWLKDGVELTDG-RHH 4944

Query: 414  YRIRVEGKKHILIIEGATKADAAEYS 439
            +  ++      L+I G  +ADA  Y+
Sbjct: 4945 HIDQLGDGTCSLLITGLDRADAGCYT 4970



 Score = 36.6 bits (83), Expect = 0.14
 Identities = 44/206 (21%), Positives = 77/206 (37%), Gaps = 42/206 (20%)

Query: 730 PSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGL------DG-----YV 778
           P   +RP   +        L+   V + T  + W       AAG       DG      +
Sbjct: 10  PRFLTRPKAFVVSVGKDATLSCQIVGNPTPQVSWEKDQQPVAAGARFRLAQDGDLYRLTI 69

Query: 779 LEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVK 838
           L+     +  ++   ++ I +  F   GL  DA+         AA A +  ++       
Sbjct: 70  LDLALGDSGQYVCRARNAIGEA-FAAVGLQVDAE---------AACAEQAPHF------- 112

Query: 839 EIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDG---AEIDKNQINIR 895
            ++ P  IR+    + T+  RVG          G PRP ++W KDG    E D  ++ + 
Sbjct: 113 -LLRPTSIRVREGSEATFRCRVG----------GSPRPAVSWSKDGRRLGEPDGPRVRVE 161

Query: 896 NSETDTIIFIRKAERSHSGKYDLQVK 921
                + + IR A     G Y+++ +
Sbjct: 162 ELGEASALRIRAARPRDGGTYEVRAE 187



 Score = 36.6 bits (83), Expect = 0.14
 Identities = 38/166 (22%), Positives = 61/166 (36%), Gaps = 20/166 (12%)

Query: 999  ITELVIGNEYYFRVFSENMCGLSE-------DATMTK-ESAVIARDGKIY---------- 1040
            IT +V  +   +R  +EN  G+S        D T T  ++A  A +   Y          
Sbjct: 5186 ITAVVPADMGVYRCLAENSMGVSSTKAELRVDLTSTDYDTAADATESSSYFSAQGYLSSR 5245

Query: 1041 -KNPVYEDFDFSEAPMFTQPLVNTYAIAGYN-ATLNCSVRGNPKPKITWMKNKVAIVDDP 1098
             +       D  + P   + L +     G   A     V+G P P++ W K+   +    
Sbjct: 5246 EQEGTESTTDEGQLPQVVEELRDLQVAPGTRLAKFQLKVKGYPAPRLYWFKDGQPLTASA 5305

Query: 1099 RYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVK 1144
              RM   + + TLEI   +  D G Y     N +G      +L V+
Sbjct: 5306 HIRMTDKKILHTLEIISVTREDSGQYAAYISNAMGAAYSSARLLVR 5351



 Score = 35.8 bits (81), Expect = 0.24
 Identities = 21/71 (29%), Positives = 30/71 (42%), Gaps = 2/71 (2%)

Query: 1056 FTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRK 1115
            F   L N  A  G  ATL C +  +    + W K    + D  RY +  +  +C L+IR 
Sbjct: 3276 FIGKLRNKEATEGATATLRCEL--SKAAPVEWRKGSETLRDGDRYCLRQDGAMCELQIRG 3333

Query: 1116 PSPYDGGTYCC 1126
             +  D   Y C
Sbjct: 3334 LAMVDAAEYSC 3344



 Score = 35.8 bits (81), Expect = 0.24
 Identities = 21/71 (29%), Positives = 30/71 (42%), Gaps = 2/71 (2%)

Query: 1056 FTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRK 1115
            F + + N  A  G  A L C +  N    + W K    + D  RY +  +   C L+IR 
Sbjct: 3540 FIEDVKNQEAREGATAVLQCEL--NSAAPVEWRKGSETLRDGDRYSLRQDGTKCELQIRG 3597

Query: 1116 PSPYDGGTYCC 1126
             +  D G Y C
Sbjct: 3598 LAMADTGEYSC 3608



 Score = 35.4 bits (80), Expect = 0.31
 Identities = 21/71 (29%), Positives = 30/71 (42%), Gaps = 2/71 (2%)

Query: 1056 FTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRK 1115
            FT+ L N  A  G  A L C +  +    + W K    + D  R+ +  +   C L+IR 
Sbjct: 3628 FTEGLRNEEATEGATAVLRCEL--SKMAPVEWWKGHETLRDGDRHSLRQDGARCELQIRG 3685

Query: 1116 PSPYDGGTYCC 1126
                D G Y C
Sbjct: 3686 LVAEDAGEYLC 3696



 Score = 34.7 bits (78), Expect = 0.53
 Identities = 20/64 (31%), Positives = 32/64 (50%), Gaps = 1/64 (1%)

Query: 1065 AIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTY 1124
            A AG +ATL+C V    + ++TW K+   +    + RM +      L +++    D G Y
Sbjct: 1546 AEAGTSATLSCEV-AQAQTEVTWYKDGKKLSSSSKVRMEAVGCTRRLVVQEAGQADAGEY 1604

Query: 1125 CCKA 1128
             CKA
Sbjct: 1605 SCKA 1608



 Score = 34.3 bits (77), Expect = 0.70
 Identities = 18/62 (29%), Positives = 30/62 (48%), Gaps = 2/62 (3%)

Query: 1065 AIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTY 1124
            +I G  ATL C +  +    + W K + ++ D  R+ +  +  VC L+I   +  D G Y
Sbjct: 3373 SIEGATATLRCEL--SKAAPVEWRKGRESLRDGDRHSLRQDGAVCELQICGLAVADAGEY 3430

Query: 1125 CC 1126
             C
Sbjct: 3431 SC 3432



 Score = 34.3 bits (77), Expect = 0.70
 Identities = 21/71 (29%), Positives = 31/71 (43%), Gaps = 2/71 (2%)

Query: 1056 FTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRK 1115
            F + L N  A  G  ATL C +  +    + W K    + D  R+ +  +   C L+IR 
Sbjct: 3716 FIEGLRNEEATEGDTATLWCEL--SKAAPVEWRKGHETLRDGDRHSLRQDGSRCELQIRG 3773

Query: 1116 PSPYDGGTYCC 1126
             +  D G Y C
Sbjct: 3774 LAVVDAGEYSC 3784



 Score = 34.3 bits (77), Expect = 0.70
 Identities = 17/59 (28%), Positives = 29/59 (49%), Gaps = 2/59 (3%)

Query: 860  VGEAVNLVIPFQGKPRPELTWKKDG--AEIDKNQINIRNSETDTIIFIRKAERSHSGKY 916
            +GE V L     G P+P ++W KDG   ++D + I I + +    + +       SG+Y
Sbjct: 6027 LGETVKLACRVTGTPKPVISWYKDGKAVQVDPHHILIEDPDGSCALILDSLTGVDSGQY 6085



 Score = 33.5 bits (75), Expect = 1.2
 Identities = 20/83 (24%), Positives = 36/83 (43%), Gaps = 1/83 (1%)

Query: 1055 MFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIR 1114
            + T+PL         +  L+C  R  PK  + W K+   +    +++M     +  L I 
Sbjct: 2470 VLTRPLEPKTGRELQSVVLSCDFRPAPKA-VQWYKDDTPLSPSEKFKMSLEGQMAELRIL 2528

Query: 1115 KPSPYDGGTYCCKAVNDLGTVEI 1137
            +  P D G Y C+A +   + E+
Sbjct: 2529 RLMPADAGVYRCQAGSAHSSTEV 2551



 Score = 33.5 bits (75), Expect = 1.2
 Identities = 20/80 (25%), Positives = 34/80 (42%), Gaps = 1/80 (1%)

Query: 1058 QPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPS 1117
            +PL + +   G +  L C +     P + W+K++ AI    +Y +     +  L IR  S
Sbjct: 2831 KPLEDQWVAPGEDVELRCELSRAGTP-VHWLKDRKAIRKSQKYDVVCEGTMAMLVIRGAS 2889

Query: 1118 PYDGGTYCCKAVNDLGTVEI 1137
              D G Y C+      T  +
Sbjct: 2890 LKDAGEYTCEVEASKSTASL 2909



 Score = 33.1 bits (74), Expect = 1.6
 Identities = 19/64 (29%), Positives = 30/64 (46%), Gaps = 1/64 (1%)

Query: 1065 AIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTY 1124
            A AG  A L+C V   P+ ++TW K+   +    + RM        L +++    D G Y
Sbjct: 1178 AEAGTTAMLSCEV-AQPQTEVTWYKDGKKLSSSSKVRMEVKGCTRRLVVQQVGKADAGEY 1236

Query: 1125 CCKA 1128
             C+A
Sbjct: 1237 SCEA 1240



 Score = 33.1 bits (74), Expect = 1.6
 Identities = 23/81 (28%), Positives = 35/81 (43%), Gaps = 7/81 (8%)

Query: 288  QVDKGGRVRF--VVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDS 345
            Q   GG  +F  ++E  DP+  V WYK+  ++  ST+   + +G    L + +    D  
Sbjct: 6367 QAQTGGTAQFEAIIE-GDPQPSVTWYKDSVQLVDSTRLSQQQEGTTYSLVLRHVASKDAG 6425

Query: 346  EYYV----TAGDEKCSTELFV 362
             Y      T G   C  EL V
Sbjct: 6426 VYTCLAQNTGGQVLCKAELLV 6446



 Score = 32.7 bits (73), Expect = 2.0
 Identities = 19/71 (26%), Positives = 30/71 (42%), Gaps = 5/71 (7%)

Query: 1073 LNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDL 1132
            L C V  +P+  + W K+ V +    +Y      G   L +   SP D G Y C     +
Sbjct: 2666 LQCEV-SDPEAHVVWRKDGVQLGPSDKYDFLHTAGTRGLVVHDVSPEDAGLYTC----HV 2720

Query: 1133 GTVEIECKLEV 1143
            G+ E   ++ V
Sbjct: 2721 GSEETRARVRV 2731



 Score = 32.3 bits (72), Expect = 2.7
 Identities = 20/92 (21%), Positives = 45/92 (48%), Gaps = 3/92 (3%)

Query: 861 GEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINI--RNSETDTIIFIRKAERSHSGKYDL 918
           G+   L     G+P+PE  WKKDG  + + + ++   +++ + ++ I   ++S  G Y  
Sbjct: 252 GKHARLSCYVTGEPKPETVWKKDGQLVTEGRRHVVYEDAQENFVLKILFCKQSDRGLYTC 311

Query: 919 QVKVDKFVETASIDIQIIDRPGPPQIVKIEDV 950
               +   +T S  + ++  P  P   +++D+
Sbjct: 312 TAS-NLVGQTYSSVLVVVREPAVPFKKRLQDL 342



 Score = 32.3 bits (72), Expect = 2.7
 Identities = 18/61 (29%), Positives = 29/61 (47%)

Query: 288  QVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEY 347
            QV  G  V   +E+     EV W+K  + I+P  ++    +G Q++L I      D  EY
Sbjct: 4634 QVAAGEDVSLELEVVAEAGEVIWHKGMERIQPGGRFEVVSQGRQQMLVIKGFTAEDQGEY 4693

Query: 348  Y 348
            +
Sbjct: 4694 H 4694



 Score = 32.3 bits (72), Expect = 2.7
 Identities = 25/107 (23%), Positives = 43/107 (40%), Gaps = 5/107 (4%)

Query: 542  HVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTE 601
            H   PP + +   D    V    G   + E  I G+P P   W + D   +  S R+  +
Sbjct: 6352 HTARPPSMQVTIED----VQAQTGGTAQFEAIIEGDPQPSVTWYK-DSVQLVDSTRLSQQ 6406

Query: 602  SYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPP 648
                + +LV+      D+GVY    +N  G+     ++ V+   + P
Sbjct: 6407 QEGTTYSLVLRHVASKDAGVYTCLAQNTGGQVLCKAELLVLGGDNEP 6453



 Score = 32.0 bits (71), Expect = 3.5
 Identities = 22/82 (26%), Positives = 39/82 (47%), Gaps = 2/82 (2%)

Query: 1065 AIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTY 1124
            A AG +ATL+C V    + ++TW K+   +    +  M +      L +++    D G Y
Sbjct: 902  AEAGASATLSCEV-AQAQTEVTWYKDGKKLSSSSKVCMEATGCTRRLVVQQAGQADAGEY 960

Query: 1125 CCKAVNDLGTVEIECKLEVKVI 1146
             C+A     +  ++ K E KV+
Sbjct: 961  SCEAGGQRLSFHLDVK-EPKVV 981



 Score = 32.0 bits (71), Expect = 3.5
 Identities = 17/62 (27%), Positives = 32/62 (51%), Gaps = 1/62 (1%)

Query: 1067 AGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCC 1126
            AG +ATL+C V    + ++TW K+   +    + R+ +   +  L +++    D G Y C
Sbjct: 1272 AGASATLSCEV-AQAQTEVTWYKDGKKLSSSSKVRIEAAGCMRQLVVQQAGQADAGEYTC 1330

Query: 1127 KA 1128
            +A
Sbjct: 1331 EA 1332



 Score = 31.6 bits (70), Expect = 4.5
 Identities = 18/64 (28%), Positives = 32/64 (50%), Gaps = 1/64 (1%)

Query: 1065 AIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTY 1124
            A AG +ATL+C V    + ++TW K+   +    + R+ +      L +++    D G Y
Sbjct: 1638 AEAGASATLSCEV-AQAQTEVTWYKDGKKLSSSSKVRVEAVGCTRRLVVQQAGQADAGEY 1696

Query: 1125 CCKA 1128
             C+A
Sbjct: 1697 SCEA 1700



 Score = 31.6 bits (70), Expect = 4.5
 Identities = 21/71 (29%), Positives = 30/71 (42%), Gaps = 2/71 (2%)

Query: 1056 FTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRK 1115
            FT+ L N  A+ G  A L C +  +    + W K    + D  RY +      C L+I  
Sbjct: 3452 FTEGLRNEEAVEGATAMLWCEL--SKVAPVEWRKGPENLRDGDRYILRQEGTRCELQICG 3509

Query: 1116 PSPYDGGTYCC 1126
             +  D G Y C
Sbjct: 3510 LAMADAGEYLC 3520



 Score = 30.8 bits (68), Expect = 7.7
 Identities = 19/77 (24%), Positives = 36/77 (46%)

Query: 565  GNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHI 624
            G+ LRLE  ++ +   +A W +    + +G      +    + +L+I   +R D+G Y  
Sbjct: 4912 GDALRLECVVASKADVRARWLKDGVELTDGRHHHIDQLGDGTCSLLITGLDRADAGCYTC 4971

Query: 625  NLKNEAGEAHASIKVKV 641
             + N+ G+   S  V V
Sbjct: 4972 QVSNKFGQVTHSACVVV 4988


>gi|118572606 hemicentin 1 [Homo sapiens]
          Length = 5635

 Score =  123 bits (309), Expect = 9e-28
 Identities = 199/871 (22%), Positives = 345/871 (39%), Gaps = 92/871 (10%)

Query: 304  PKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVT----AGDEKCSTE 359
            P  ++ W+K+G+ +      + E     ++L + N +  D   Y  T    AG +    +
Sbjct: 1481 PFPDIHWFKDGKPLFLGDPNV-ELLDRGQVLHLKNARRNDKGRYQCTVSNAAGKQAKDIK 1539

Query: 360  LFVREPP-IMVTKQLEDTTAYCGERVELECEVSE-DDANVKWFKNGEEIIPGPKSRYRIR 417
            L +  PP I       D +      ++LECE        + W+K+G+ I+   ++ Y   
Sbjct: 1540 LTIYIPPSIKGGNVTTDISVLINSLIKLECETRGLPMPAITWYKDGQPIMSSSQALYI-- 1597

Query: 418  VEGKKHILIIEGATKADAAEYS--VMTTGGQSSAKLSVDL--KPL---KILTPLTDQTVN 470
               K   L I  A  +D+A Y+  V    G +     VD+   P+    + TPL  Q V 
Sbjct: 1598 --DKGQYLHIPRAQVSDSATYTCHVANVAGTAEKSFHVDVYVPPMIEGNLATPLNKQVV- 1654

Query: 471  LGKEICLKCEISENIPG--KWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVF 528
            +   + L+C+ + N      W K+G+PV+ +D +++   G+  KL I +A   D G Y+ 
Sbjct: 1655 IAHSLTLECKAAGNPSPILTWLKDGVPVKANDNIRIEAGGK--KLEIMSAQEIDRGQYIC 1712

Query: 529  APD--AYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSR 586
                 A    +  +V V+ PP I  +G D  +   V+  N L L+  ++G PPP  MW +
Sbjct: 1713 VATSVAGEKEIKYEVDVLVPPAI--EGGDETSYFIVMVNNLLELDCHVTGSPPPTIMWLK 1770

Query: 587  GDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPD 646
              + I E  G    +   +   LVI  A+  ++G+Y     N AG+     +V V     
Sbjct: 1771 DGQLIDERDG---FKILLNGRKLVIAQAQVSNTGLYRCMAANTAGDHKKEFEVTV----- 1822

Query: 647  PPVAPTVTEVG-DDWCIMNWEPPAYD---GGSPILGY-FIERKKKQSSRWMRLNFDLCKE 701
              V PT+   G  +  ++ ++P A      G P     +++  +  ++    L       
Sbjct: 1823 -HVPPTIKSSGLSERVVVKYKPVALQCIANGIPNPSITWLKDDQPVNTAQGNLKIQSSGR 1881

Query: 702  TTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTM 761
                 K ++E  A      A NA G       ++  + L V  PP+L     + + TV +
Sbjct: 1882 VLQIAKTLLED-AGRYTCVATNAAG------ETQQHIQLHVHEPPSLEDAGKMLNETVLV 1934

Query: 762  RWRPPDHIGAAG-----LDGYVLEYCFEGTEDWIVANK-DLIDKTKFTITGLPTDAKIFV 815
                     AAG     +  Y       G+      N+  +ID     I    +DA I+ 
Sbjct: 1935 SNPVQLECKAAGNPVPVITWYKDNRLLSGSTSMTFLNRGQIIDIESAQI----SDAGIY- 1989

Query: 816  RVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPR 875
            +  A+N+AGA+E  +YS  + V      P I    ++       V   V L    +G P 
Sbjct: 1990 KCVAINSAGATE-LFYSLQVHV-----APSISGSNNMVAVV---VNNPVRLECEARGIPA 2040

Query: 876  PELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQI 935
            P LTW KDG+ +      ++      I+ +  A+ S +G+Y          +   ID+++
Sbjct: 2041 PSLTWLKDGSPVSSFSNGLQVLSGGRILALTSAQISDTGRYTCVAVNAAGEKQRDIDLRV 2100

Query: 936  IDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRT 995
                 PP I+  E    +NV++  +   +          + ++D       T ++  H  
Sbjct: 2101 Y---VPPNIMGEE----QNVSVLISQAVE---------LLCQSDAIPPPTLTWLKDGHPL 2144

Query: 996  SATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIA-RDGKIYKNPVYEDFDFSEAP 1054
                   +  N    ++       + +    T E+  +A +  K Y   ++   +   + 
Sbjct: 2145 LKKPGLSISENRSVLKIEDAQ---VQDTGRYTCEATNVAGKTEKNYNVNIWVPPNIGGSD 2201

Query: 1055 MFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIR 1114
              TQ  V    I G   +L C   G P P + W K    ++ D   R+    G   L+I 
Sbjct: 2202 ELTQLTV----IEGNLISLLCESSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQIS 2257

Query: 1115 KPSPYDGGTYCCKAVNDLGTVEIECKLEVKV 1145
                 D   Y C A N  GT + E  L+V +
Sbjct: 2258 IAEKSDAALYSCVASNVAGTAKKEYNLQVYI 2288



 Score =  117 bits (293), Expect = 6e-26
 Identities = 183/846 (21%), Positives = 313/846 (36%), Gaps = 133/846 (15%)

Query: 351  AGDEKCSTELFVREPPIMVTKQLEDTTAY----CGERVELECEVS-EDDANVKWFKNGEE 405
            AG ++    L V+EPP +   +    T +      +R+E  C         +KW  NG E
Sbjct: 1247 AGTDETEITLHVQEPPTVEDLEPPYNTTFQERVANQRIEFPCPAKGTPKPTIKWLHNGRE 1306

Query: 406  IIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKP-----LKI 460
            +  G +    I  +G   +L+I   T  D  EY  +      + +   +LK      +K 
Sbjct: 1307 LT-GREPGISILEDGT--LLVIASVTPYDNGEYICVAVNEAGTTERKYNLKVHVPPVIKD 1363

Query: 461  LTPLTDQTVNLGKEICLKCEISENIPGK---WTKNGLPVQESDRLKVVHKGRIHKLVIAN 517
               +T+ +V L +   L CE+ E  P     W K+ + V ES  ++ V+ G+I KL    
Sbjct: 1364 KEQVTNVSVLLNQLTNLFCEV-EGTPSPIIMWYKDNVQVTESSTIQTVNNGKILKLF--R 1420

Query: 518  ALTEDEGDYVFAPDAYNVTLPAK----VHVIDPPKIILDGLDADNTVTVIAGNKLRLEIP 573
            A  ED G Y  +  A N+   ++    + V+ PP II  G +  N V+V+    + LE  
Sbjct: 1421 ATPEDAGRY--SCKAINIAGTSQKYFNIDVLVPPTII--GTNFPNEVSVVLNRDVALECQ 1476

Query: 574  ISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEA 633
            + G P P   W +  K +  G   +  E       L +  A R+D G Y   + N AG+ 
Sbjct: 1477 VKGTPFPDIHWFKDGKPLFLGDPNV--ELLDRGQVLHLKNARRNDKGRYQCTVSNAAGKQ 1534

Query: 634  HASIKVKVVDFPDPPVAPTVTEV---------------GDDWCIMNWEPPAYDGGSPILG 678
               IK+ +   P        T++               G     + W    Y  G PI+ 
Sbjct: 1535 AKDIKLTIYIPPSIKGGNVTTDISVLINSLIKLECETRGLPMPAITW----YKDGQPIM- 1589

Query: 679  YFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFV 738
                      S    L  D  +       ++ +   Y   +   N  G ++ S     +V
Sbjct: 1590 ----------SSSQALYIDKGQYLHIPRAQVSDSATYTCHV--ANVAGTAEKSFHVDVYV 1637

Query: 739  PLAVT-SPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLI 797
            P  +  +  T L    V   ++T+  +      AAG    +L +  +G    + AN ++ 
Sbjct: 1638 PPMIEGNLATPLNKQVVIAHSLTLECK------AAGNPSPILTWLKDGVP--VKANDNIR 1689

Query: 798  ----DKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLK 853
                 K    ++    D   ++ V A + AG  E KY        +++ PP I       
Sbjct: 1690 IEAGGKKLEIMSAQEIDRGQYICV-ATSVAGEKEIKY------EVDVLVPPAIEGGDETS 1742

Query: 854  QTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDK----------NQINIRNSETDTII 903
              +I  V   + L     G P P + W KDG  ID+           ++ I  ++     
Sbjct: 1743 Y-FIVMVNNLLELDCHVTGSPPPTIMWLKDGQLIDERDGFKILLNGRKLVIAQAQVSNTG 1801

Query: 904  FIR----KAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTW 959
              R         H  ++++ V V   ++++ +  +++ +  P  +  I +    N ++TW
Sbjct: 1802 LYRCMAANTAGDHKKEFEVTVHVPPTIKSSGLSERVVVKYKPVALQCIAN-GIPNPSITW 1860

Query: 960  TPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCG 1019
                   N A     IQ + +      T++E   R +   T      + + ++       
Sbjct: 1861 LKDDQPVNTAQGNLKIQSSGRVLQIAKTLLEDAGRYTCVATNAAGETQQHIQLHVHEPPS 1920

Query: 1020 LSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRG 1079
            L +   M  E+ +++       NPV                            L C   G
Sbjct: 1921 LEDAGKMLNETVLVS-------NPV---------------------------QLECKAAG 1946

Query: 1080 NPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIEC 1139
            NP P ITW K+   ++       F N+G   ++I      D G Y C A+N  G  E+  
Sbjct: 1947 NPVPVITWYKDN-RLLSGSTSMTFLNRGQ-IIDIESAQISDAGIYKCVAINSAGATELFY 2004

Query: 1140 KLEVKV 1145
             L+V V
Sbjct: 2005 SLQVHV 2010



 Score =  114 bits (284), Expect = 7e-25
 Identities = 189/886 (21%), Positives = 328/886 (37%), Gaps = 111/886 (12%)

Query: 303  DPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTELFV 362
            +P   + WYK+ + +  ST   F ++G  +I+ I + Q++D   Y   A +   +TELF 
Sbjct: 1947 NPVPVITWYKDNRLLSGSTSMTFLNRG--QIIDIESAQISDAGIYKCVAINSAGATELFY 2004

Query: 363  R-----EPPIMVTKQLEDTTAYCGERVELECEVSEDDA-NVKWFKNGEEIIPGPKSRYRI 416
                   P I  +  +          V LECE     A ++ W K+G    P       +
Sbjct: 2005 SLQVHVAPSISGSNNM--VAVVVNNPVRLECEARGIPAPSLTWLKDGS---PVSSFSNGL 2059

Query: 417  RVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLK---PLKILTPLTDQTVNLGK 473
            +V     IL +  A  +D   Y+ +        +  +DL+   P  I+    + +V + +
Sbjct: 2060 QVLSGGRILALTSAQISDTGRYTCVAVNAAGEKQRDIDLRVYVPPNIMGEEQNVSVLISQ 2119

Query: 474  EICLKCEISENIPGK---WTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAP 530
             + L C+ S+ IP     W K+G P+ +   L +     + K  I +A  +D G Y    
Sbjct: 2120 AVELLCQ-SDAIPPPTLTWLKDGHPLLKKPGLSISENRSVLK--IEDAQVQDTGRYTC-- 2174

Query: 531  DAYNVTLPAK----VHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMW-S 585
            +A NV    +    V++  PP I   G D    +TVI GN + L    SG PPP  +W  
Sbjct: 2175 EATNVAGKTEKNYNVNIWVPPNI--GGSDELTQLTVIEGNLISLLCESSGIPPPNLIWKK 2232

Query: 586  RGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFP 645
            +G   + +  GR+R  S      L I IAE+ D+ +Y     N AG A     ++V    
Sbjct: 2233 KGSPVLTDSMGRVRILS--GGRQLQISIAEKSDAALYSCVASNVAGTAKKEYNLQVY--- 2287

Query: 646  DPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFE 705
               + PT+T  G        E     G S  L   ++     +  WM+    L K    E
Sbjct: 2288 ---IRPTITNSGSH----PTEIIVTRGKSISLECEVQGIPPPTVTWMKDGHPLIKAKGVE 2340

Query: 706  PKKMIEGVAYEVRIFAVN------AIGISKPSMPSRPFVPLAVTSPPTLL-------TVD 752
               + EG   +++   V+       + ++   M  + +  L+V +PP+++        + 
Sbjct: 2341 --ILDEGHILQLKNIHVSDTGRYVCVAVNVAGMTDKKY-DLSVHAPPSIIGNHRSPENIS 2397

Query: 753  SVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAK 812
             V   +V++         A+G+    + +  +G    +  +  ++   +       T   
Sbjct: 2398 VVEKNSVSLTCE------ASGIPLPSITWFKDGWPVSLSNSVRILSGGRMLRLMQTTMED 2451

Query: 813  IFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQG 872
                   V  A   E K +   +LV     PP I     L+   ++   ++V L     G
Sbjct: 2452 AGQYTCVVRNAAGEERKIFGLSVLV-----PPHIVGENTLEDVKVKE-KQSVTLTCEVTG 2505

Query: 873  KPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASID 932
             P PE+TW KDG  + +++ +         + I   +  H+G+Y          ++ S  
Sbjct: 2506 NPVPEITWHKDGQPLQEDEAH-HIISGGRFLQITNVQVPHTGRYTCLASSPAGHKSRSFS 2564

Query: 933  IQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHY 992
            + +   P                  T      DGN       +            V E Y
Sbjct: 2565 LNVFVSP------------------TIAGVGSDGNPEDVTVILNSPTS------LVCEAY 2600

Query: 993  HRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSE 1052
                ATIT    G           + G      +  +     R   +  N   E     E
Sbjct: 2601 SYPPATITWFKDGTPLESNRNIRILPGGRTLQILNAQEDNAGRYSCVATNEAGEMIKHYE 2660

Query: 1053 APMFTQPLVNTYAIAG-------------YNATLNCSVRGNPKPKITWMKNKVAIVDDPR 1099
              ++  P++N   + G                TL C     P   ++W K+   +  D  
Sbjct: 2661 VKVYIPPIINKGDLWGPGLSPKEVKIKVNNTLTLECEAYAIPSASLSWYKDGQPLKSDDH 2720

Query: 1100 YRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVKV 1145
              + +N    TL+I++    D G Y C A N  G  E++  + ++V
Sbjct: 2721 VNIAANGH--TLQIKEAQISDTGRYTCVASNIAGEDELDFDVNIQV 2764



 Score =  112 bits (280), Expect = 2e-24
 Identities = 206/889 (23%), Positives = 329/889 (37%), Gaps = 120/889 (13%)

Query: 303  DPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTA----GDEKCST 358
            +P  E +W KN   +  +        G    L I   Q+ D  EY   A    G    +T
Sbjct: 917  NPIPERRWIKNSAMLLQNPYITVRSDGS---LHIERVQLQDGGEYTCVASNVAGTNNKTT 973

Query: 359  ELFVRE-PPIMVTKQLEDTTAYCGERVELECEVSEDDA-NVKWFKNGEEIIPGPKSRYRI 416
             + V   P I   +Q+  T    G  V L C+ S +   +V W K GE +I    +++  
Sbjct: 974  SVVVHVLPTIQHGQQILSTIE--GIPVTLPCKASGNPKPSVIWSKKGE-LISTSSAKFSA 1030

Query: 417  RVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQ--------- 467
              +G  +++   G    ++ EY    T     AK  V L          DQ         
Sbjct: 1031 GADGSLYVVSPGGE---ESGEYVCTATNTAGYAKRKVQLTVYVRPRVFGDQRGLSQDKPV 1087

Query: 468  --TVNLGKEICLKCEISENIPG--KWTKNGLPVQE-SDRLKVVHKGRIHKLVIANALTED 522
              +V  G+E+ L CE+    P    W K    +   S R   +  G    + I    T D
Sbjct: 1088 EISVLAGEEVTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPSG---SMKITETRTSD 1144

Query: 523  EGDYVFAPD--AYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPP 580
             G Y+      A NVT   K++V  PPKI          + V  G ++ +     G P P
Sbjct: 1145 SGMYLCVATNIAGNVTQAVKLNVHVPPKI----QRGPKHLKVQVGQRVDIPCNAQGTPLP 1200

Query: 581  KAMWSRGDKA-IMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKV 639
               WS+G    +++G   +   S PD  TL ID A   D+G+Y     N AG     I +
Sbjct: 1201 VITWSKGGSTMLVDGEHHV---SNPD-GTLSIDQATPSDAGIYTCVATNIAGTDETEITL 1256

Query: 640  KVVDFP-----DPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRL 694
             V + P     +PP   T  E   +  I   E P    G+P          K + +W+  
Sbjct: 1257 HVQEPPTVEDLEPPYNTTFQERVANQRI---EFPCPAKGTP----------KPTIKWLHN 1303

Query: 695  NFDLCKETTFEPKKMIEGVAYEVRIFAVN--------AIGISKPSMPSRPFVPLAVTSPP 746
              +L   T  EP   I      + I +V          + +++     R +  L V  PP
Sbjct: 1304 GREL---TGREPGISILEDGTLLVIASVTPYDNGEYICVAVNEAGTTERKY-NLKVHVPP 1359

Query: 747  TLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKF--TI 804
             +   + VT+ +V +           G    ++ +  +  +    +    ++  K     
Sbjct: 1360 VIKDKEQVTNVSVLLNQLTNLFCEVEGTPSPIIMWYKDNVQVTESSTIQTVNNGKILKLF 1419

Query: 805  TGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAV 864
               P DA  +   KA+N AG S+ KY++  +LV     PP I I  +        +   V
Sbjct: 1420 RATPEDAGRY-SCKAINIAGTSQ-KYFNIDVLV-----PPTI-IGTNFPNEVSVVLNRDV 1471

Query: 865  NLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDK 924
             L    +G P P++ W KDG  +     N+   +   ++ ++ A R+  G+Y   V    
Sbjct: 1472 ALECQVKGTPFPDIHWFKDGKPLFLGDPNVELLDRGQVLHLKNARRNDKGRYQCTVSNAA 1531

Query: 925  FVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKS-- 982
              +   I + I   P          + G NV         D +  I      + + +   
Sbjct: 1532 GKQAKDIKLTIYIPP---------SIKGGNVT-------TDISVLINSLIKLECETRGLP 1575

Query: 983  MEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGK---- 1038
            M   T  +      ++   L I    Y  +       +S+ AT T   A +A   +    
Sbjct: 1576 MPAITWYKDGQPIMSSSQALYIDKGQYLHI---PRAQVSDSATYTCHVANVAGTAEKSFH 1632

Query: 1039 --IYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVD 1096
              +Y  P+ E            PL N   +  ++ TL C   GNP P +TW+K+ V +  
Sbjct: 1633 VDVYVPPMIEG-------NLATPL-NKQVVIAHSLTLECKAAGNPSPILTWLKDGVPVKA 1684

Query: 1097 DPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVKV 1145
            +   R+    G   LEI      D G Y C A +  G  EI+ +++V V
Sbjct: 1685 NDNIRI--EAGGKKLEIMSAQEIDRGQYICVATSVAGEKEIKYEVDVLV 1731



 Score =  100 bits (249), Expect = 8e-21
 Identities = 197/883 (22%), Positives = 337/883 (38%), Gaps = 115/883 (13%)

Query: 304  PKLEVKWYKNGQEI---RPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTE- 359
            PK  +KW  NG+E+    P    + +      +L I +    D+ EY   A +E  +TE 
Sbjct: 1294 PKPTIKWLHNGRELTGREPGISILED----GTLLVIASVTPYDNGEYICVAVNEAGTTER 1349

Query: 360  ---LFVREPPIMVTK-QLEDTTAYCGERVELECEVSEDDAN-VKWFKNGEEIIPGPKSRY 414
               L V  PP++  K Q+ + +    +   L CEV    +  + W+K+  ++        
Sbjct: 1350 KYNLKVHVPPVIKDKEQVTNVSVLLNQLTNLFCEVEGTPSPIIMWYKDNVQVTESS---- 1405

Query: 415  RIRVEGKKHILIIEGATKADAAEYS--VMTTGGQSSAKLSVD--LKPLKILTPLTDQ-TV 469
             I+      IL +  AT  DA  YS   +   G S    ++D  + P  I T   ++ +V
Sbjct: 1406 TIQTVNNGKILKLFRATPEDAGRYSCKAINIAGTSQKYFNIDVLVPPTIIGTNFPNEVSV 1465

Query: 470  NLGKEICLKCEISEN-IPG-KWTKNGLPVQESD-RLKVVHKGRIHKLVIANALTEDEGDY 526
             L +++ L+C++     P   W K+G P+   D  ++++ +G++  L + NA   D+G Y
Sbjct: 1466 VLNRDVALECQVKGTPFPDIHWFKDGKPLFLGDPNVELLDRGQV--LHLKNARRNDKGRY 1523

Query: 527  --VFAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMW 584
                +  A       K+ +  PP I   G +    ++V+  + ++LE    G P P   W
Sbjct: 1524 QCTVSNAAGKQAKDIKLTIYIPPSI--KGGNVTTDISVLINSLIKLECETRGLPMPAITW 1581

Query: 585  SRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDF 644
             +  + IM  S  +  +       L I  A+  DS  Y  ++ N AG A  S  V V   
Sbjct: 1582 YKDGQPIMSSSQALYIDK---GQYLHIPRAQVSDSATYTCHVANVAGTAEKSFHVDVY-V 1637

Query: 645  PDPPVAPTVTEVGDDWCI---MNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKE 701
            P        T +     I   +  E  A    SPIL +  +    +++  +R+     K 
Sbjct: 1638 PPMIEGNLATPLNKQVVIAHSLTLECKAAGNPSPILTWLKDGVPVKANDNIRIEAGGKKL 1697

Query: 702  TTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPT----LLTVDSVTDT 757
                 +++  G   +    A +  G  +        VP A+         ++ V+++ + 
Sbjct: 1698 EIMSAQEIDRG---QYICVATSVAGEKEIKYEVDVLVPPAIEGGDETSYFIVMVNNLLEL 1754

Query: 758  TVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRV 817
               +   PP  I     DG +++   +G +  +   K +I + + + TGL        R 
Sbjct: 1755 DCHVTGSPPPTIMWL-KDGQLIDE-RDGFKILLNGRKLVIAQAQVSNTGL-------YRC 1805

Query: 818  KAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPE 877
             A N AG    K +   + V     PP I+     ++  ++    A+  +    G P P 
Sbjct: 1806 MAANTAG-DHKKEFEVTVHV-----PPTIKSSGLSERVVVKYKPVALQCIA--NGIPNPS 1857

Query: 878  LTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETAS-IDIQII 936
            +TW KD   ++  Q N++   +  ++ I K     +G+Y   V  +   ET   I + + 
Sbjct: 1858 ITWLKDDQPVNTAQGNLKIQSSGRVLQIAKTLLEDAGRYTC-VATNAAGETQQHIQLHVH 1916

Query: 937  DRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTS 996
            +   PP +     +  E V              +    +Q   K +     VI  Y    
Sbjct: 1917 E---PPSLEDAGKMLNETV--------------LVSNPVQLECKAAGNPVPVITWYKD-- 1957

Query: 997  ATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYK---------NPVYED 1047
                 L+ G        S +M  L+    +  ESA I+ D  IYK           ++  
Sbjct: 1958 ---NRLLSG--------STSMTFLNRGQIIDIESAQIS-DAGIYKCVAINSAGATELFYS 2005

Query: 1048 FDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSN-- 1105
                 AP  +        +      L C  RG P P +TW+K      D      FSN  
Sbjct: 2006 LQVHVAPSISGSNNMVAVVVNNPVRLECEARGIPAPSLTWLK------DGSPVSSFSNGL 2059

Query: 1106 ---QGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVKV 1145
                G   L +      D G Y C AVN  G  + +  L V V
Sbjct: 2060 QVLSGGRILALTSAQISDTGRYTCVAVNAAGEKQRDIDLRVYV 2102



 Score = 99.0 bits (245), Expect = 2e-20
 Identities = 208/877 (23%), Positives = 325/877 (37%), Gaps = 123/877 (14%)

Query: 304  PKLEVKWYKNGQEIRPS-TKYIFEHKGCQRILFINNCQMTDDSEYYV----TAGDEKCST 358
            P   + W K+G  +  +  +Y     G    L I +  +TD   Y       AG ++   
Sbjct: 3740 PTPRITWRKDGAVLAGNHARYSILENG---FLHIQSAHVTDTGRYLCMATNAAGTDRRRI 3796

Query: 359  ELFVREPPIMVTKQLEDTTAYCGERVELECEVSE-DDANVKWFKNGEEI-IPGPKSRYRI 416
            +L V  PP  +     + T     +  L CE +     ++ W KNG  + +   ++ YR+
Sbjct: 3797 DLQVHVPP-SIAPGPTNMTVIVNVQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRL 3855

Query: 417  RVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLK---PLKILTPLTDQTVNLGK 473
               G    L+I   +  D A Y    T G    K +VDL    P  I    TD  V    
Sbjct: 3856 LSSGS---LVIISPSVDDTATYECTVTNGAGDDKRTVDLTVQVPPSIADEPTDFLVTKHA 3912

Query: 474  EICLKCEISENIPGK---WTKNGLPV-QESDRLKVVHKGRIHKLVIANALTEDEGDY--V 527
               + C  S  +P     WTKNG+ +    D  +++  G I   ++A  L    G Y  V
Sbjct: 3913 PAVITCTAS-GVPFPSIHWTKNGIRLLPRGDGYRILSSGAIE--ILATQLNH-AGRYTCV 3968

Query: 528  FAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRG 587
                A +      +HV +PP I        + + VI  N + L    +G P P   W + 
Sbjct: 3969 ARNAAGSAHRHVTLHVHEPPVI----QPQPSELHVILNNPILLPCEATGTPSPFITWQK- 4023

Query: 588  DKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDP 647
            +   +  SGR    +   S  L I  A R+D+G Y    +N AG A   IK+ V      
Sbjct: 4024 EGINVNTSGR--NHAVLPSGGLQISRAVREDAGTYMCVAQNPAGTALGKIKLNV------ 4075

Query: 648  PVAPTVTEVGDDWCIMNWEPPAY----DGGSP--ILGYFIERKKKQSSRWMRLNFDLCKE 701
             V P ++    ++ I   +P       DG  P  I  +   R   +S R   L+    + 
Sbjct: 4076 QVPPVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAIVESIRQRVLSSGSLQI 4135

Query: 702  TTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDS-------- 753
               +P     G A      A N  G S  S      VP  + S     TV+         
Sbjct: 4136 AFVQP-----GDAGHYTCMAANVAGSSSTSTKLTVHVPPRIRSTEGHYTVNENSQAILPC 4190

Query: 754  VTD--TTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDA 811
            V D   T  + W+  D++  A L G   +Y  E   + I+ N  L D   +T        
Sbjct: 4191 VADGIPTPAINWK-KDNVLLANLLG---KYTAEPYGELILENVVLEDSGFYTCV------ 4240

Query: 812  KIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQ 871
                   A NAAG       +  + +   + P    +P  +        GE + L     
Sbjct: 4241 -------ANNAAGED-----THTVSLTVHVLPTFTELPGDVS----LNKGEQLRLSCKAT 4284

Query: 872  GKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASI 931
            G P P+LTW  +   I  +  ++ N  ++ +  I +  +  SG Y         V TA  
Sbjct: 4285 GIPLPKLTWTFNNNIIPAHFDSV-NGHSELV--IERVSKEDSGTY---------VCTAEN 4332

Query: 932  DIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEW---FTV 988
             +  +   G    VK   V+  +    W  P   G  AI    ++     +++W      
Sbjct: 4333 SVGFVKAIG-FVYVKEPPVFKGDYPSNWIEPL--GGNAILNCEVKGDPTPTIQWNRKGVD 4389

Query: 989  IEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDF 1048
            IE  HR    I +L  G+   +   +E+    +     T E+ V+ R   +         
Sbjct: 4390 IEISHR----IRQLGNGSLAIYGTVNEDAGDYT--CVATNEAGVVERSMSL--------- 4434

Query: 1049 DFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGV 1108
                 P+ T   V T   AG    LNC   G P+P ITW +   +I  D R  + SN  +
Sbjct: 4435 TLQSPPIITLEPVETVINAGGKIILNCQATGEPQPTITWSRQGHSISWDDRVNVLSNNSL 4494

Query: 1109 CTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVKV 1145
               + +K    D   + C A N +G+V +   + V+V
Sbjct: 4495 YIADAQKE---DTSEFECVARNLMGSVLVRVPVIVQV 4528



 Score = 97.4 bits (241), Expect = 7e-20
 Identities = 189/901 (20%), Positives = 332/901 (36%), Gaps = 134/901 (14%)

Query: 304  PKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCST----E 359
            P   + W+K+G  +  +        G  R L I N Q  +   Y   A +E        E
Sbjct: 2603 PPATITWFKDGTPLESNRNIRILPGG--RTLQILNAQEDNAGRYSCVATNEAGEMIKHYE 2660

Query: 360  LFVREPPIMVTKQL-------EDTTAYCGERVELECEV-SEDDANVKWFKNGEEIIPGPK 411
            + V  PPI+    L       ++        + LECE  +   A++ W+K+G+ +    K
Sbjct: 2661 VKVYIPPIINKGDLWGPGLSPKEVKIKVNNTLTLECEAYAIPSASLSWYKDGQPL----K 2716

Query: 412  SRYRIRVEGKKHILIIEGATKADAAEYSVMTTG--GQSSAKLSVDLKPLKILTPLTD--- 466
            S   + +    H L I+ A  +D   Y+ + +   G+      V+++       L +   
Sbjct: 2717 SDDHVNIAANGHTLQIKEAQISDTGRYTCVASNIAGEDELDFDVNIQVPPSFQKLWEIGN 2776

Query: 467  ----------QTVNLGKEICLKCEISENIPGK--WTKNGLPVQESDRLKVVHKGRIHKLV 514
                      + V +   I L CE +   P    W K+G P+  SD++ ++  GR+  L 
Sbjct: 2777 MLDTGRNGEAKDVIINNPISLYCETNAAPPPTLTWYKDGHPLTSSDKVLILPGGRV--LQ 2834

Query: 515  IANALTEDEGDY--VFAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEI 572
            I  A  ED G Y  V   +A   +L   V V+ PP I     D    VTV+      +E 
Sbjct: 2835 IPRAKVEDAGRYTCVAVNEAGEDSLQYDVRVLVPPIIKGANSDLPEEVTVLVNKSALIEC 2894

Query: 573  PISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGE 632
              SG P P+  W +  + ++E       +   +   L I   +  D G Y    +N AG 
Sbjct: 2895 LSSGSPAPRNSWQKDGQPLLEDD---HHKFLSNGRILQILNTQITDIGRYVCVAENTAGS 2951

Query: 633  A--HASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSR 690
            A  + ++ V V      P +  +T V +++  +  E   +    P L +    K +Q  +
Sbjct: 2952 AKKYFNLNVHVPPSVIGPKSENLTVVVNNFISLTCEVSGFP--PPDLSWL---KNEQPIK 3006

Query: 691  WMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVT--SPPTL 748
                   +    T +  +       E    A+N  G SK       +VP ++      +L
Sbjct: 3007 LNTNTLIVPGGRTLQIIRAKVSDGGEYTCIAINQAGESKKKFSLTVYVPPSIKDHDSESL 3066

Query: 749  LTVDSVTDTTVTMRWRP---PDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTIT 805
              V+    T+V++       P  +     +G ++    E T   I+A+  ++   K  + 
Sbjct: 3067 SVVNVREGTSVSLECESNAVPPPVITWYKNGRMIT---ESTHVEILADGQMLHIKKAEV- 3122

Query: 806  GLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVN 865
               +D   +V  +A+N AG  +  ++        +  PP I  P   ++  +  +   V 
Sbjct: 3123 ---SDTGQYV-CRAINVAGRDDKNFH------LNVYVPPSIEGPE--REVIVETISNPVT 3170

Query: 866  LVIPFQGKPRPELTWKKDGAEID-KNQINIRNSETDTIIFIRKAERSHSGKY-----DLQ 919
            L     G P P + W K+   I+  + + +R     + + I +++ S SG Y     +++
Sbjct: 3171 LTCDATGIPPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNME 3230

Query: 920  VKVDKFVETASIDIQIIDRPGPPQIVKIE---DV---WGENVALTWTPPKDDGNAAITGY 973
             K  K+     + IQ+     PP +   E   DV    GENV L       + N   T  
Sbjct: 3231 GKAQKYY---FLSIQV-----PPSVAGAEIPSDVSVLLGENVELVC-----NANGIPTPL 3277

Query: 974  TIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVI 1033
                 D K                    +  G     RV +         +T+    A+ 
Sbjct: 3278 IQWLKDGK-------------------PIASGETERIRVSANG-------STLNIYGALT 3311

Query: 1034 ARDGK---IYKNPVYEDFDFSEAPMFTQPLV--------NTYAIAGYNATLNCSVRGNPK 1082
            +  GK   +  NP  E+       ++  P +            +   +  + C   G P 
Sbjct: 3312 SDTGKYTCVATNPAGEEDRIFNLNVYVTPTIRGNKDEAEKLMTLVDTSINIECRATGTPP 3371

Query: 1083 PKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLE 1142
            P+I W+KN + +      R+ +   V  + I +    D   Y C A N  G       L+
Sbjct: 3372 PQINWLKNGLPLPLSSHIRLLAAGQV--IRIVRAQVSDVAVYTCVASNRAGVDNKHYNLQ 3429

Query: 1143 V 1143
            V
Sbjct: 3430 V 3430



 Score = 94.4 bits (233), Expect = 6e-19
 Identities = 154/668 (23%), Positives = 251/668 (37%), Gaps = 103/668 (15%)

Query: 302  ADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVT----AGDEKCS 357
            A P   + WYK+GQ ++          G    L I   Q++D   Y       AG+++  
Sbjct: 2700 AIPSASLSWYKDGQPLKSDDHVNIAANG--HTLQIKEAQISDTGRYTCVASNIAGEDELD 2757

Query: 358  TELFVREPP-----------IMVTKQLEDTTAYCGERVELECEV-SEDDANVKWFKNGEE 405
             ++ ++ PP           +   +  E         + L CE  +     + W+K+G  
Sbjct: 2758 FDVNIQVPPSFQKLWEIGNMLDTGRNGEAKDVIINNPISLYCETNAAPPPTLTWYKDGHP 2817

Query: 406  IIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPL- 464
            +    K    + +     +L I  A   DA  Y+ +         L  D++ L  + P+ 
Sbjct: 2818 LTSSDK----VLILPGGRVLQIPRAKVEDAGRYTCVAVNEAGEDSLQYDVRVL--VPPII 2871

Query: 465  --------TDQTVNLGKEICLKCEISENIP---GKWTKNGLPVQESDRLKVVHKGRIHKL 513
                     + TV + K   ++C +S   P     W K+G P+ E D  K +  GRI  L
Sbjct: 2872 KGANSDLPEEVTVLVNKSALIEC-LSSGSPAPRNSWQKDGQPLLEDDHHKFLSNGRI--L 2928

Query: 514  VIANALTEDEGDYVFAPDAYNVTLPAK------VHVIDPPKIILDGLDADNTVTVIAGNK 567
             I N    D G YV    A N    AK      VHV  PP +I  G  ++N +TV+  N 
Sbjct: 2929 QILNTQITDIGRYVCV--AENTAGSAKKYFNLNVHV--PPSVI--GPKSEN-LTVVVNNF 2981

Query: 568  LRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLK 627
            + L   +SG PPP   W + ++ I   +    T   P   TL I  A+  D G Y     
Sbjct: 2982 ISLTCEVSGFPPPDLSWLKNEQPIKLNT---NTLIVPGGRTLQIIRAKVSDGGEYTCIAI 3038

Query: 628  NEAGEAHASIKVKVVDFPD----PPVAPTVTEVGDDW-----CIMNWEPPAYDGGSPILG 678
            N+AGE+     + V   P        + +V  V +       C  N  PP      P++ 
Sbjct: 3039 NQAGESKKKFSLTVYVPPSIKDHDSESLSVVNVREGTSVSLECESNAVPP------PVIT 3092

Query: 679  YFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFV 738
            ++   +    S  + +   L        KK       +    A+N  G    +     +V
Sbjct: 3093 WYKNGRMITESTHVEI---LADGQMLHIKKAEVSDTGQYVCRAINVAGRDDKNFHLNVYV 3149

Query: 739  PLAVTSPPTLLTVDSVTD-TTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLI 797
            P ++  P   + V+++++  T+T          A G+           T  W+  +K + 
Sbjct: 3150 PPSIEGPEREVIVETISNPVTLT--------CDATGIP--------PPTIAWLKNHKRIE 3193

Query: 798  DKTKFTITGLPTDAKIFVRVKAVNAAG-----ASEPKYYSQPILVKEIIEPPKI---RIP 849
            +     +  L   +K+ +     + +G     AS  +  +Q      I  PP +    IP
Sbjct: 3194 NSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQKYYFLSIQVPPSVAGAEIP 3253

Query: 850  RHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQI-NIRNSETDTIIFIRKA 908
              +       +GE V LV    G P P + W KDG  I   +   IR S   + + I  A
Sbjct: 3254 SDVSVL----LGENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGA 3309

Query: 909  ERSHSGKY 916
              S +GKY
Sbjct: 3310 LTSDTGKY 3317



 Score = 93.6 bits (231), Expect = 1e-18
 Identities = 193/893 (21%), Positives = 303/893 (33%), Gaps = 140/893 (15%)

Query: 304  PKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTE---- 359
            P   + W KN + I  S             L I   Q +D   Y   A + +   +    
Sbjct: 3179 PPPTIAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQKYYF 3238

Query: 360  LFVREPPIMVTKQL-EDTTAYCGERVELECEVSEDDAN-VKWFKNGEEIIPGPKSRYRIR 417
            L ++ PP +   ++  D +   GE VEL C  +      ++W K+G+ I  G   R R+ 
Sbjct: 3239 LSIQVPPSVAGAEIPSDVSVLLGENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVS 3298

Query: 418  VEGKKHILIIEGATKADAAEYSVMTTGGQSSA----KLSVDLKPL---------KILTPL 464
              G    L I GA  +D  +Y+ + T           L+V + P          K++T L
Sbjct: 3299 ANGST--LNIYGALTSDTGKYTCVATNPAGEEDRIFNLNVYVTPTIRGNKDEAEKLMT-L 3355

Query: 465  TDQTVNLGKEICLKCEISENIPGK--WTKNGLPVQESDRLKVVHKGRIHKLVIANALTED 522
             D ++N+      +C  +   P +  W KNGLP+  S  ++++  G++ ++V A      
Sbjct: 3356 VDTSINI------ECRATGTPPPQINWLKNGLPLPLSSHIRLLAAGQVIRIVRAQVSDVA 3409

Query: 523  EGDYVFAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKA 582
                V +  A        + V  PP   +D       +TV+ G+   +     G P P  
Sbjct: 3410 VYTCVASNRAGVDNKHYNLQVFAPPN--MDNSMGTEEITVLKGSSTSMACITDGTPAPSM 3467

Query: 583  MWSRGDKAI-MEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKV 641
             W R  + + ++    + T        L +  AE +DSG Y     NEAGE      +KV
Sbjct: 3468 AWLRDGQPLGLDAHLTVSTHGM----VLQLLKAETEDSGKYTCIASNEAGEVSKHFILKV 3523

Query: 642  VDFPDPPVAPTVTEVGDDWCIMN--WEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLC 699
            +   +PP      E  +   I+N   E      G P               WM+    L 
Sbjct: 3524 L---EPPHINGSEEHEEISVIVNNPLELTCIASGIP----------APKMTWMKDGRPL- 3569

Query: 700  KETTFEPKKMIEGVAYEVRIFAVNAIG-----ISKPSMPSRPFVPLAVTSPPTLLTVDSV 754
               T + + +  G    +    V   G      S P+        + V  PP +   D  
Sbjct: 3570 -PQTDQVQTLGGGEVLRISTAQVEDTGRYTCLASSPAGDDDKEYLVRVHVPPNIAGTDEP 3628

Query: 755  TDTTVTMRWR----------PPDHI----GAAGLDGYVLEYCFEGTEDWIVANKDLIDKT 800
             D TV    +          PP  I        L          G     + N DL D  
Sbjct: 3629 RDITVLRNRQVTLECKSDAVPPPVITWLRNGERLQATPRVRILSGGRYLQINNADLGDTA 3688

Query: 801  KFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRV 860
             +T               A N AG +  ++     +   I   P+  +    K T +  +
Sbjct: 3689 NYTCV-------------ASNIAGKTTREFILTVNVPPNIKGGPQSLVILLNKSTVLECI 3735

Query: 861  GEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQV 920
             E V         P P +TW+KDGA +  N       E +  + I+ A  + +G+Y    
Sbjct: 3736 AEGV---------PTPRITWRKDGAVLAGNHARYSILE-NGFLHIQSAHVTDTGRYLCMA 3785

Query: 921  KVDKFVETASIDIQI----IDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQ 976
                  +   ID+Q+       PGP  +  I +V           PK   N    G+ + 
Sbjct: 3786 TNAAGTDRRRIDLQVHVPPSIAPGPTNMTVIVNVQTTLACEATGIPKPSINWRKNGHLLN 3845

Query: 977  KADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSEN---MCGLSEDATMTKESAVI 1033
                                      V  N+  +R+ S     +   S D T T E  V 
Sbjct: 3846 --------------------------VDQNQNSYRLLSSGSLVIISPSVDDTATYECTVT 3879

Query: 1034 ARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVA 1093
               G   +     D      P       +        A + C+  G P P I W KN + 
Sbjct: 3880 NGAGDDKRT---VDLTVQVPPSIADEPTDFLVTKHAPAVITCTASGVPFPSIHWTKNGIR 3936

Query: 1094 IVDDPR---YRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1143
            ++  PR   YR+ S+  +   EI        G Y C A N  G+      L V
Sbjct: 3937 LL--PRGDGYRILSSGAI---EILATQLNHAGRYTCVARNAAGSAHRHVTLHV 3984



 Score = 82.4 bits (202), Expect = 2e-15
 Identities = 197/890 (22%), Positives = 322/890 (36%), Gaps = 122/890 (13%)

Query: 304  PKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVT----AGDEKCSTE 359
            P  +VKW+K   E+RPST  I +      +L I   Q  D  +Y       AG       
Sbjct: 729  PPPQVKWFKGDLELRPSTFLIID--PLLGLLKIQETQDLDAGDYTCVAINEAGRATGKIT 786

Query: 360  LFVREPPIMVTKQLEDTTAYCGERVELECEV-SEDDANVKWFK-NGEEIIPGPKSRYRIR 417
            L V  PP+ + ++  D +   G  V L C V    +  +KW + +   I   P S   I 
Sbjct: 787  LDVGSPPVFI-QEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSIS 845

Query: 418  V--EGKKHILIIEGATKAD---AAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLG 472
                G   IL +  + K      AE        +++  ++  + PL  ++P     +  G
Sbjct: 846  QLRTGALFILNLWASDKGTYICEAENQFGKIQSETTVTVTGLVAPLIGISPSVANVIE-G 904

Query: 473  KEICLKCEISENIP---GKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFA 529
            +++ L C +    P    +W KN   + ++  + V   G +H   I     +D G+Y   
Sbjct: 905  QQLTLPCTLLAGNPIPERRWIKNSAMLLQNPYITVRSDGSLH---IERVQLQDGGEYTCV 961

Query: 530  PD----AYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWS 585
                    N T    VHV+  P I          ++ I G  + L    SG P P  +WS
Sbjct: 962  ASNVAGTNNKTTSVVVHVL--PTI----QHGQQILSTIEGIPVTLPCKASGNPKPSVIWS 1015

Query: 586  RGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFP 645
            +  + I   S +    +  D S  V+     ++SG Y     N AG A   +++ V   P
Sbjct: 1016 KKGELISTSSAKFSAGA--DGSLYVVS-PGGEESGEYVCTATNTAGYAKRKVQLTVYVRP 1072

Query: 646  -----------DPPVAPTV---TEVGDDWCIMNWEPP--AYDGGSPILGYFIERKKKQSS 689
                       D PV  +V    EV     + +  PP   +   + ++  F  R     S
Sbjct: 1073 RVFGDQRGLSQDKPVEISVLAGEEVTLPCEVKSLPPPIITWAKETQLISPFSPRHTFLPS 1132

Query: 690  RWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLL 749
              M++      ET      M   VA  +      A             V L V  PP + 
Sbjct: 1133 GSMKIT-----ETRTSDSGMYLCVATNIAGNVTQA-------------VKLNVHVPPKIQ 1174

Query: 750  TVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTIT---G 806
                     V  R   P    A G    V+ +  +G    +V  +  +     T++    
Sbjct: 1175 RGPKHLKVQVGQRVDIP--CNAQGTPLPVITWS-KGGSTMLVDGEHHVSNPDGTLSIDQA 1231

Query: 807  LPTDAKIFVRVKAVNAAGASEPK---YYSQPILVKEIIEPPKIRIPRHLKQTYIRRV-GE 862
             P+DA I+  V A N AG  E +   +  +P  V++ +EPP          T+  RV  +
Sbjct: 1232 TPSDAGIYTCV-ATNIAGTDETEITLHVQEPPTVED-LEPP-------YNTTFQERVANQ 1282

Query: 863  AVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKV 922
             +    P +G P+P + W  +G E+   +  I   E  T++ I       +G+Y + V V
Sbjct: 1283 RIEFPCPAKGTPKPTIKWLHNGRELTGREPGISILEDGTLLVIASVTPYDNGEY-ICVAV 1341

Query: 923  DKFVETA---SIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKAD 979
            ++   T    ++ + +     PP I   E V   +V L                 ++   
Sbjct: 1342 NEAGTTERKYNLKVHV-----PPVIKDKEQVTNVSVLL--------NQLTNLFCEVEGTP 1388

Query: 980  KKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAV-IARDGK 1038
               + W+   +   + + + T   + N    ++F        EDA      A+ IA   +
Sbjct: 1389 SPIIMWY---KDNVQVTESSTIQTVNNGKILKLFR----ATPEDAGRYSCKAINIAGTSQ 1441

Query: 1039 IYKNPVYEDFDFSEAPMF--TQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKN-KVAIV 1095
             Y N      D    P    T        +   +  L C V+G P P I W K+ K   +
Sbjct: 1442 KYFN-----IDVLVPPTIIGTNFPNEVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLFL 1496

Query: 1096 DDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVKV 1145
             DP   +     V  L ++     D G Y C   N  G    + KL + +
Sbjct: 1497 GDPNVELLDRGQV--LHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTIYI 1544



 Score = 75.5 bits (184), Expect = 3e-13
 Identities = 151/664 (22%), Positives = 242/664 (36%), Gaps = 91/664 (13%)

Query: 303  DPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYV----TAGDEKCST 358
            +P  E+ W+K+GQ ++    +     G  R L I N Q+     Y       AG +  S 
Sbjct: 2506 NPVPEITWHKDGQPLQEDEAHHIISGG--RFLQITNVQVPHTGRYTCLASSPAGHKSRSF 2563

Query: 359  ELFVREPPIMV----TKQLEDTTAYCGERVELECEV-SEDDANVKWFKNGEEIIPGPKSR 413
             L V   P +         ED T        L CE  S   A + WFK+G  +    +S 
Sbjct: 2564 SLNVFVSPTIAGVGSDGNPEDVTVILNSPTSLVCEAYSYPPATITWFKDGTPL----ESN 2619

Query: 414  YRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSA----KLSVDLKPL--------KIL 461
              IR+      L I  A + +A  YS + T          ++ V + P+          L
Sbjct: 2620 RNIRILPGGRTLQILNAQEDNAGRYSCVATNEAGEMIKHYEVKVYIPPIINKGDLWGPGL 2679

Query: 462  TPLTDQTVNLGKEICLKCEISENIPG---KWTKNGLPVQESDRLKVVHKGRIHKLVIANA 518
            +P  +  + +   + L+CE +  IP     W K+G P++  D + +   G  H L I  A
Sbjct: 2680 SP-KEVKIKVNNTLTLECE-AYAIPSASLSWYKDGQPLKSDDHVNIAANG--HTLQIKEA 2735

Query: 519  LTEDEGDY--VFAPDAYNVTLPAKVHVIDPPKI--------ILDGLDADNTVTVIAGNKL 568
               D G Y  V +  A    L   V++  PP          +LD         VI  N +
Sbjct: 2736 QISDTGRYTCVASNIAGEDELDFDVNIQVPPSFQKLWEIGNMLDTGRNGEAKDVIINNPI 2795

Query: 569  RLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKN 628
             L    +  PPP   W +    +       +    P    L I  A+ +D+G Y     N
Sbjct: 2796 SLYCETNAAPPPTLTWYKDGHPLTSSD---KVLILPGGRVLQIPRAKVEDAGRYTCVAVN 2852

Query: 629  EAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQS 688
            EAGE      V+V+      V P +     D   +  E       S ++           
Sbjct: 2853 EAGEDSLQYDVRVL------VPPIIKGANSD---LPEEVTVLVNKSALIECLSSGSPAPR 2903

Query: 689  SRWMRLNFDLCKETTFEPKKMIEGVAYEVR-----------IFAVNAIGISKPSMPSRPF 737
            + W +    L ++     K +  G   ++              A N  G +K        
Sbjct: 2904 NSWQKDGQPLLEDD--HHKFLSNGRILQILNTQITDIGRYVCVAENTAGSAKKYFNLNVH 2961

Query: 738  VPLAVTSPP----TLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVAN 793
            VP +V  P     T++  + ++ T     + PPD           L      T   IV  
Sbjct: 2962 VPPSVIGPKSENLTVVVNNFISLTCEVSGFPPPDLSWLKNEQPIKL-----NTNTLIVPG 3016

Query: 794  KDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLK 853
                 +T   I    +D   +  + A+N AG S+ K +S  + V     PP I+      
Sbjct: 3017 ----GRTLQIIRAKVSDGGEYTCI-AINQAGESKKK-FSLTVYV-----PPSIKDHDSES 3065

Query: 854  QTYIR-RVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSH 912
             + +  R G +V+L       P P +TW K+G  I ++  ++       ++ I+KAE S 
Sbjct: 3066 LSVVNVREGTSVSLECESNAVPPPVITWYKNGRMITES-THVEILADGQMLHIKKAEVSD 3124

Query: 913  SGKY 916
            +G+Y
Sbjct: 3125 TGQY 3128



 Score = 75.1 bits (183), Expect = 4e-13
 Identities = 93/343 (27%), Positives = 139/343 (40%), Gaps = 43/343 (12%)

Query: 350 TAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEV-SEDDANVKWFKNGEEIIP 408
           +AG  +  T   V EPP ++     + T   GER  L C + S  D N+ W +N  ++  
Sbjct: 504 SAGTGRAQTFFDVSEPPPVIQVP-NNVTVTPGERAVLTCLIISAVDYNLTWQRNDRDVRL 562

Query: 409 GPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTT--GGQSSAKLSVDLK-PLKILTPLT 465
              +R R         L ++     DA EY  M +  GG S+A + + ++ P K+     
Sbjct: 563 AEPARIRTLANLS---LELKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQEPPKVTVMPK 619

Query: 466 DQTVNLGKEICLKCEISENIPGK--WTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDE 523
           +Q+   G E+ + C  +     K  WT N + +  S R ++   G    L I NA  +D 
Sbjct: 620 NQSFTGGSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMTSDGT---LFIKNAAPKDA 676

Query: 524 GDY------VFAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGE 577
           G Y          D  N TL      I+ PK+++      + + V  G+   +E   SG 
Sbjct: 677 GIYGCLASNSAGTDKQNSTL----RYIEAPKLMV----VQSELLVALGDITVMECKTSGI 728

Query: 578 PPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASI 637
           PPP+  W +GD  +   +  I     P    L I   +  D+G Y     NEAG A   I
Sbjct: 729 PPPQVKWFKGDLELRPSTFLIID---PLLGLLKIQETQDLDAGDYTCVAINEAGRATGKI 785

Query: 638 KVKVVDFPDPPV-----APTVTEVGDDWCIMNWEPPAYDGGSP 675
               +D   PPV     A    E+G      N   P Y  G P
Sbjct: 786 ---TLDVGSPPVFIQEPADVSMEIGS-----NVTLPCYVQGYP 820



 Score = 68.9 bits (167), Expect = 3e-11
 Identities = 89/362 (24%), Positives = 148/362 (40%), Gaps = 28/362 (7%)

Query: 302  ADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYV----TAGDEKCS 357
            A P   + WYKNG+ I  ST       G  ++L I   +++D  +Y       AG +  +
Sbjct: 3085 AVPPPVITWYKNGRMITESTHVEILADG--QMLHIKKAEVSDTGQYVCRAINVAGRDDKN 3142

Query: 358  TELFVREPPIMVTKQLEDTTAYCGERVELECEVSE-DDANVKWFKNGEEIIPGPKSRYRI 416
              L V  PP +   + E         V L C+ +      + W KN + I        RI
Sbjct: 3143 FHLNVYVPPSIEGPEREVIVETISNPVTLTCDATGIPPPTIAWLKNHKRIENSDSLEVRI 3202

Query: 417  RVEGKKHILIIEGATKADAAEYSVMTTGGQSSAK----LSVDLKPLKILTPL-TDQTVNL 471
               G K  L I  +  +D+  Y+ + +  +  A+    LS+ + P      + +D +V L
Sbjct: 3203 LSGGSK--LQIARSQHSDSGNYTCIASNMEGKAQKYYFLSIQVPPSVAGAEIPSDVSVLL 3260

Query: 472  GKEICLKCEISENIPG---KWTKNGLPVQ--ESDRLKVVHKGRIHKLVIANALTEDEGDY 526
            G+ + L C  +  IP    +W K+G P+   E++R++V   G    L I  ALT D G Y
Sbjct: 3261 GENVELVCN-ANGIPTPLIQWLKDGKPIASGETERIRVSANG--STLNIYGALTSDTGKY 3317

Query: 527  --VFAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMW 584
              V    A        ++V   P I  +  +A+  +T++    + +E   +G PPP+  W
Sbjct: 3318 TCVATNPAGEEDRIFNLNVYVTPTIRGNKDEAEKLMTLV-DTSINIECRATGTPPPQINW 3376

Query: 585  SRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDF 644
             +    +   S             + I  A+  D  VY     N AG  +    ++V   
Sbjct: 3377 LKNGLPLPLSS---HIRLLAAGQVIRIVRAQVSDVAVYTCVASNRAGVDNKHYNLQVFAP 3433

Query: 645  PD 646
            P+
Sbjct: 3434 PN 3435



 Score = 57.4 bits (137), Expect = 8e-08
 Identities = 34/83 (40%), Positives = 40/83 (48%), Gaps = 3/83 (3%)

Query: 1052 EAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTL 1111
            E P  T    N     G   ++ CS  G PKPKI W  N + IV   RYRM S+    TL
Sbjct: 610  EPPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIAWTVNDMFIVGSHRYRMTSDG---TL 666

Query: 1112 EIRKPSPYDGGTYCCKAVNDLGT 1134
             I+  +P D G Y C A N  GT
Sbjct: 667  FIKNAAPKDAGIYGCLASNSAGT 689



 Score = 48.5 bits (114), Expect = 4e-05
 Identities = 65/311 (20%), Positives = 116/311 (37%), Gaps = 30/311 (9%)

Query: 837  VKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRN 896
            + +++EPP I      ++  +  V   + L     G P P++TW KDG  + +    ++ 
Sbjct: 3520 ILKVLEPPHINGSEEHEEISVI-VNNPLELTCIASGIPAPKMTWMKDGRPLPQTD-QVQT 3577

Query: 897  SETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVA 956
                 ++ I  A+   +G+Y          +     +++     PP I   ++       
Sbjct: 3578 LGGGEVLRISTAQVEDTGRYTCLASSPAGDDDKEYLVRV---HVPPNIAGTDE------- 3627

Query: 957  LTWTPPKDDGNAAITGYTIQ-KADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSE 1015
                 P+D         T++ K+D       T + +  R  AT    ++    Y ++   
Sbjct: 3628 -----PRDITVLRNRQVTLECKSDAVPPPVITWLRNGERLQATPRVRILSGGRYLQI--- 3679

Query: 1016 NMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNC 1075
            N   L + A  T  ++ IA  GK  +  +      +  P       +   +   +  L C
Sbjct: 3680 NNADLGDTANYTCVASNIA--GKTTREFI---LTVNVPPNIKGGPQSLVILLNKSTVLEC 3734

Query: 1076 SVRGNPKPKITWMKNKVAIV-DDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGT 1134
               G P P+ITW K+   +  +  RY +  N     L I+     D G Y C A N  GT
Sbjct: 3735 IAEGVPTPRITWRKDGAVLAGNHARYSILENG---FLHIQSAHVTDTGRYLCMATNAAGT 3791

Query: 1135 VEIECKLEVKV 1145
                  L+V V
Sbjct: 3792 DRRRIDLQVHV 3802



 Score = 45.1 bits (105), Expect = 4e-04
 Identities = 74/347 (21%), Positives = 130/347 (37%), Gaps = 52/347 (14%)

Query: 819  AVNAAGAS----EPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKP 874
            A N AG      E K Y  PI+ K  +  P +  P+ +K     +V   + L       P
Sbjct: 2648 ATNEAGEMIKHYEVKVYIPPIINKGDLWGPGLS-PKEVKI----KVNNTLTLECEAYAIP 2702

Query: 875  RPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQ 934
               L+W KDG  + K+  ++  +     + I++A+ S +G+Y          +    D+ 
Sbjct: 2703 SASLSWYKDGQPL-KSDDHVNIAANGHTLQIKEAQISDTGRYTCVASNIAGEDELDFDVN 2761

Query: 935  IIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHR 994
            I     PP   K+ ++               GN   TG   +  + K +     I  Y  
Sbjct: 2762 I---QVPPSFQKLWEI---------------GNMLDTG---RNGEAKDVIINNPISLYCE 2800

Query: 995  TSA----TITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGK---IYKNPVYED 1047
            T+A    T+T    G+       S+ +  L     +    A +   G+   +  N   ED
Sbjct: 2801 TNAAPPPTLTWYKDGHPL---TSSDKVLILPGGRVLQIPRAKVEDAGRYTCVAVNEAGED 2857

Query: 1048 FDFSEAPMFTQPLVN---------TYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDP 1098
                +  +   P++             +   +A + C   G+P P+ +W K+   +++D 
Sbjct: 2858 SLQYDVRVLVPPIIKGANSDLPEEVTVLVNKSALIECLSSGSPAPRNSWQKDGQPLLEDD 2917

Query: 1099 RYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVKV 1145
             ++  SN  +  L+I      D G Y C A N  G+ +    L V V
Sbjct: 2918 HHKFLSNGRI--LQILNTQITDIGRYVCVAENTAGSAKKYFNLNVHV 2962



 Score = 45.1 bits (105), Expect = 4e-04
 Identities = 81/353 (22%), Positives = 137/353 (38%), Gaps = 61/353 (17%)

Query: 809  TDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVI 868
            TD   +V V A N AG+++ KY++  + V     PP +  P+    T +  V   ++L  
Sbjct: 2936 TDIGRYVCV-AENTAGSAK-KYFNLNVHV-----PPSVIGPKSENLTVV--VNNFISLTC 2986

Query: 869  PFQGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVET 928
               G P P+L+W K+   I  N        T+T+I          G   LQ+   K  + 
Sbjct: 2987 EVSGFPPPDLSWLKNEQPIKLN--------TNTLIV--------PGGRTLQIIRAKVSDG 3030

Query: 929  ASIDIQIIDRPGPPQIVKIEDVWGENVALT-WTPP--KDDGNAAITGYTIQKADKKSMEW 985
                   I++ G  +         +  +LT + PP  KD  + +++   +++    S+E 
Sbjct: 3031 GEYTCIAINQAGESK---------KKFSLTVYVPPSIKDHDSESLSVVNVREGTSVSLEC 3081

Query: 986  FT------VIEHYHR----TSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIA- 1034
             +      VI  Y      T +T  E++   +      +E    +S+       +  +A 
Sbjct: 3082 ESNAVPPPVITWYKNGRMITESTHVEILADGQMLHIKKAE----VSDTGQYVCRAINVAG 3137

Query: 1035 RDGKIYKNPVY--EDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKV 1092
            RD K +   VY     +  E  +  + + N         TL C   G P P I W+KN  
Sbjct: 3138 RDDKNFHLNVYVPPSIEGPEREVIVETISNP-------VTLTCDATGIPPPTIAWLKNHK 3190

Query: 1093 AIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVKV 1145
             I +     +    G   L+I +    D G Y C A N  G  +    L ++V
Sbjct: 3191 RIENSDSLEVRILSGGSKLQIARSQHSDSGNYTCIASNMEGKAQKYYFLSIQV 3243



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 45/180 (25%), Positives = 73/180 (40%), Gaps = 15/180 (8%)

Query: 477 LKCEISENIPG--KWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDY--VFAPDA 532
           + C +   +P    + +NG+ +     LK   +     L IA     DEG Y  +    A
Sbjct: 449 IPCSVDSLLPFTLSFVRNGVTLGVDQYLK---ESASVNLDIAKVTLSDEGFYECIAVSSA 505

Query: 533 YNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAI- 591
                     V +PP +I       N VTV  G +  L   I         W R D+ + 
Sbjct: 506 GTGRAQTFFDVSEPPPVI----QVPNNVTVTPGERAVLTCLIISAVDYNLTWQRNDRDVR 561

Query: 592 MEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAP 651
           +    RIRT +   + +L +   + +D+G YH  + +E G + AS+ + V + P   V P
Sbjct: 562 LAEPARIRTLA---NLSLELKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQEPPKVTVMP 618



 Score = 41.2 bits (95), Expect = 0.006
 Identities = 63/339 (18%), Positives = 126/339 (37%), Gaps = 54/339 (15%)

Query: 814  FVRVKAVNAAGASEPKYY---SQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPF 870
            F    AV++AG    + +   S+P        PP I++P ++  T     GE   L    
Sbjct: 496  FYECIAVSSAGTGRAQTFFDVSEP--------PPVIQVPNNVTVT----PGERAVLTCLI 543

Query: 871  QGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETAS 930
                   LTW+++  ++   +     +  +  + ++  + + +G+Y   V  +     AS
Sbjct: 544  ISAVDYNLTWQRNDRDVRLAEPARIRTLANLSLELKSVKFNDAGEYHCMVSSEGGSSAAS 603

Query: 931  IDIQIIDRPGPPQIVKIED-VWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVI 989
            + + + + P    + K +    G  V++           + TGY      K  + W    
Sbjct: 604  VFLTVQEPPKVTVMPKNQSFTGGSEVSIM---------CSATGYP-----KPKIAW---- 645

Query: 990  EHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYED-- 1047
                    T+ ++ I   + +R+ S+    +   A   K++ +    G +  N    D  
Sbjct: 646  --------TVNDMFIVGSHRYRMTSDGTLFIKNAAP--KDAGIY---GCLASNSAGTDKQ 692

Query: 1048 ---FDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFS 1104
                 + EAP             G    + C   G P P++ W K  + +   P   +  
Sbjct: 693  NSTLRYIEAPKLMVVQSELLVALGDITVMECKTSGIPPPQVKWFKGDLEL--RPSTFLII 750

Query: 1105 NQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1143
            +  +  L+I++    D G Y C A+N+ G    +  L+V
Sbjct: 751  DPLLGLLKIQETQDLDAGDYTCVAINEAGRATGKITLDV 789



 Score = 38.5 bits (88), Expect = 0.037
 Identities = 25/80 (31%), Positives = 32/80 (40%)

Query: 1066 IAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYC 1125
            + G N  L C+  G P P I W+K+   I      R+  +    TL I      D G Y 
Sbjct: 3259 LLGENVELVCNANGIPTPLIQWLKDGKPIASGETERIRVSANGSTLNIYGALTSDTGKYT 3318

Query: 1126 CKAVNDLGTVEIECKLEVKV 1145
            C A N  G  +    L V V
Sbjct: 3319 CVATNPAGEEDRIFNLNVYV 3338


>gi|140560919 myomesin 1 isoform a [Homo sapiens]
          Length = 1685

 Score =  117 bits (294), Expect = 5e-26
 Identities = 86/304 (28%), Positives = 133/304 (43%), Gaps = 40/304 (13%)

Query: 580 PKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKN----EAGEAHA 635
           P+  W R    +   S  ++T    + +TL      ++D G+Y I ++     E   A+ 
Sbjct: 439 PEIQWYRNGVPLSP-SKWVQTLWSGERATLTFSHLNKEDEGLYTIRVRMGEYYEQYSAYV 497

Query: 636 SIKVKVVDFPDPPVAPT---VTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWM 692
            ++    +    P AP      E   D+ I++W+ PA DGGSPILGYFI++ +  +  W 
Sbjct: 498 FVRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSWS 557

Query: 693 RLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPL------------ 740
           + N    K   F    +IEG +Y  R+ AVN +GI  PS  S P   L            
Sbjct: 558 QCNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAALDPAEKARLKSRP 617

Query: 741 ------------------AVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYC 782
                              V  PPT L+V   T + V + W+PP   G  G+  Y +E C
Sbjct: 618 SAPWTGQIIVTEEEPSEGIVPGPPTDLSVTEATRSYVVLSWKPPGQRGHEGI-MYFVEKC 676

Query: 783 FEGTEDWIVANKDL-IDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEII 841
             GTE+W   N +L +   +F +  L        RV+  N+AG  EP   ++  +V + +
Sbjct: 677 EAGTENWQRVNTELPVKSPRFALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVVGDKL 736

Query: 842 EPPK 845
           + PK
Sbjct: 737 DIPK 740



 Score =  114 bits (284), Expect = 7e-25
 Identities = 180/759 (23%), Positives = 287/759 (37%), Gaps = 125/759 (16%)

Query: 377  TAYCGERVELECEVSE-DDANVKWFKNGEEI-IPGPKSRYRIRVEGKKHILIIEGATKAD 434
            T +  E V+L C ++   +  V W+KN   I +     +Y I      H L I G    D
Sbjct: 287  TVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGCDFED 346

Query: 435  AAEY--SVMTTGGQSSAKLSVDLK------------------PLKI-LTPL--------- 464
             A+Y  S M   G+ SA  SV +K                  PL   +TP          
Sbjct: 347  TAQYRASAMNVKGELSAYASVVVKRYKGEFDETRFHAGASTMPLSFGVTPYGYASRFEIH 406

Query: 465  -----------TDQTVNLGKEICLKCEISENIPG-KWTKNGLPVQESDRLKVVHKGRIHK 512
                         +T++LG  + +  EI    P  +W +NG+P+  S  ++ +  G    
Sbjct: 407  FDDKFDVSFGREGETMSLGCRVVITPEIKHFQPEIQWYRNGVPLSPSKWVQTLWSGERAT 466

Query: 513  LVIANALTEDEG---------DYVFAPDAYNVTLPAKVHVIDPPKIILDG--LDADNTVT 561
            L  ++   EDEG         +Y     AY     A   +   P   LD   L+A+    
Sbjct: 467  LTFSHLNKEDEGLYTIRVRMGEYYEQYSAYVFVRDADAEIEGAPAAPLDVKCLEANKDYI 526

Query: 562  VIAGNKLRLE--IPISGEPPPKA-----MWSRGDK-----AIMEGSGRIRTESYPDSSTL 609
            +I+  +  ++   PI G    K       WS+ +      A    +G I   SY      
Sbjct: 527  IISWKQPAVDGGSPILGYFIDKCEVGTDSWSQCNDTPVKFARFPVTGLIEGRSYIFRVRA 586

Query: 610  V----IDIAERDDSGVYHINLKNEAG-----EAHASIKVKVVD-------FPDPPVAPTV 653
            V    I    R    V  ++   +A       A  + ++ V +        P PP   +V
Sbjct: 587  VNKMGIGFPSRVSEPVAALDPAEKARLKSRPSAPWTGQIIVTEEEPSEGIVPGPPTDLSV 646

Query: 654  TEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDL-CKETTFEPKKMIEG 712
            TE    + +++W+PP   G   I+ YF+E+ +  +  W R+N +L  K   F    + EG
Sbjct: 647  TEATRSYVVLSWKPPGQRGHEGIM-YFVEKCEAGTENWQRVNTELPVKSPRFALFDLAEG 705

Query: 713  VAYEVRIFAVNAIGISKPSMPSRPFV---PLAVTSPPTLLTVDSVTDTTVTMRWRPPDHI 769
             +Y  R+   N+ G+ +PS  +   V    L +   P  +     TDT+V + W   +  
Sbjct: 706  KSYCFRVRCSNSAGVGEPSEATEVTVVGDKLDIPKAPGKIIPSRNTDTSVVVSWE--ESK 763

Query: 770  GAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPK 829
             A  L GY +E    G+  W   N + +  ++FT  GL T      RV+AVNAAG SE  
Sbjct: 764  DAKELVGYYIEASVAGSGKWEPCNNNPVKGSRFTCHGLVTGQSYIFRVRAVNAAGLSEYS 823

Query: 830  YYSQPILVKEII--------------EPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPR 875
              S+ I VK  I              EP  +   R           +   L+     KP 
Sbjct: 824  QDSEAIEVKAAIGGGVSPDVCPALSDEPGGLTASRGRVHEASPPTFQKDALLGSKPNKPS 883

Query: 876  -PELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYD-LQVKVDKFVETASIDI 933
             P  +      E+ K    ++   T      +KA      K D L+ K D+         
Sbjct: 884  LPSSSQNLGQTEVSKVSETVQEELTPP---PQKAAPQGKSKSDPLKKKTDR--------- 931

Query: 934  QIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTI---QKADKKSMEWFTV-I 989
                 P PP  +   + + +++ L W  P   G A ITGY +   +  D    +W    +
Sbjct: 932  ---APPSPPCDITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWREANV 988

Query: 990  EHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTK 1028
            +     +  I+ L     Y F+V + NM GL   + +++
Sbjct: 989  KAVSEEAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSE 1027



 Score = 93.2 bits (230), Expect = 1e-18
 Identities = 119/536 (22%), Positives = 202/536 (37%), Gaps = 65/536 (12%)

Query: 645  PDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSS---RWMRLNFDLCKE 701
            P PP   T  E   D  ++ W+ P   GG+ I GY++  ++       +W   N     E
Sbjct: 934  PSPPCDITCLESFRDSMVLGWKQPDKIGGAEITGYYVNYREVIDGVPGKWREANVKAVSE 993

Query: 702  TTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFV----PLAVTSPPTLLTVDSVTDT 757
              ++   + E + Y+ ++ A+N  G+  PS  S  F      +AV  PP  L    V   
Sbjct: 994  EAYKISNLKENMVYQFQVAAMNMAGLGAPSAVSECFKCEEWTIAVPGPPHSLKCSEVRKD 1053

Query: 758  TVTMRWRPPDHIGAAGLDGYV--LEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFV 815
            ++ ++W+PP H G   + GY   L+      + W   N+  I      + GL        
Sbjct: 1054 SLVLQWKPPVHSGRTPVTGYFVDLKEAKAKEDQWRGLNEAAIKNVYLKVRGLKEGVSYVF 1113

Query: 816  RVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQ---G 872
            RV+A+N AG  +P   + P++ +           R   +  +  V +   + + F+    
Sbjct: 1114 RVRAINQAGVGKPSDLAGPVVAE----------TRPGTKEVVVNVDDDGVISLNFECDKM 1163

Query: 873  KPRPELTWKKDGAEI-DKNQINIRNSETDTIIFIRKAERSHSGKYDLQV-KVDKFVETAS 930
             P+ E +W KD     D  ++ + +    T +  +       G Y   V   D    +  
Sbjct: 1164 TPKSEFSWSKDYVSTEDSPRLEVESKGNKTKMTFKDLGMDDLGIYSCDVTDTDGIASSYL 1223

Query: 931  IDIQIIDR----------PGPP--QIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKA 978
            ID + + R          P  P    + +E +    V       K  GNA +  Y     
Sbjct: 1224 IDEEELKRLLALSHEHKFPTVPVKSELAVEILEKGQVRFWMQAEKLSGNAKV-NYIFN-- 1280

Query: 979  DKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGL----SEDATMTKESAVIA 1034
            +K+  E      H  R +  I       E +     +   G      +D   T  S V+ 
Sbjct: 1281 EKEIFEGPKYKMHIDRNTGII-------EMFMEKLQDEDEGTYTFQLQDGKATNHSTVVL 1333

Query: 1035 RDGKIYKNPVYEDFDF-------SEAPMFTQPLVNTYAIAG-YNATLNCSVRGNPK-PKI 1085
              G ++K  + ++ +F        + P F + L  ++ + G  N  L C V    K   I
Sbjct: 1334 -VGDVFKK-LQKEAEFQRQEWIRKQGPHFVEYL--SWEVTGECNVLLKCKVANIKKETHI 1389

Query: 1086 TWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKL 1141
             W K++  I  D ++      G+CTL I + S  D G Y     +D G  +   KL
Sbjct: 1390 VWYKDEREISVDEKHDF--KDGICTLLITEFSKKDAGIYEVILKDDRGKDKSRLKL 1443



 Score = 57.4 bits (137), Expect = 8e-08
 Identities = 101/453 (22%), Positives = 166/453 (36%), Gaps = 92/453 (20%)

Query: 263  LKRLKRMRREEKKSAAFAKILDPAYQVDKGGRVRFVV--ELADPKLEVKWYKNGQEIRPS 320
            LKRL  +  E K      K  + A ++ + G+VRF +  E      +V +  N +EI   
Sbjct: 1229 LKRLLALSHEHKFPTVPVKS-ELAVEILEKGQVRFWMQAEKLSGNAKVNYIFNEKEIFEG 1287

Query: 321  TKY---IFEHKGCQRILFINNCQMTDDSEYYVTAGDEKC---STELFVREPPIMVTKQLE 374
             KY   I  + G    +F+   Q  D+  Y     D K    ST + V +    + K+ E
Sbjct: 1288 PKYKMHIDRNTGIIE-MFMEKLQDEDEGTYTFQLQDGKATNHSTVVLVGDVFKKLQKEAE 1346

Query: 375  --------------------DTTAYCGERVELECEVS--EDDANVKWFKNGEEIIPGPKS 412
                                + T  C   V L+C+V+  + + ++ W+K+  EI    K 
Sbjct: 1347 FQRQEWIRKQGPHFVEYLSWEVTGECN--VLLKCKVANIKKETHIVWYKDEREISVDEKH 1404

Query: 413  RYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLG 472
             ++   +G   +LI E  +K DA  Y V+    +   K  + L        + +    L 
Sbjct: 1405 DFK---DGICTLLITE-FSKKDAGIYEVILKDDRGKDKSRLKL--------VDEAFKELM 1452

Query: 473  KEICLKCEIS-----------------------ENIPGKWTKNGLPVQESDRLKVVHKGR 509
             E+C K  +S                       E++   W+ NG  ++ SDR+K    G 
Sbjct: 1453 MEVCKKIALSATDLKIQSTAEGIQLYSFVTYYVEDLKVNWSHNGSAIRYSDRVKTGVTGE 1512

Query: 510  IHKLVIANALTEDEGDYVF----APDAYNVTLPAKVHVIDPPKI---------------- 549
               L I      D+G YV         +  T+       D                    
Sbjct: 1513 QIWLQINEPTPNDKGKYVMELFDGKTGHQKTVDLSGQAYDEAYAEFQRLKQAAIAEKNRA 1572

Query: 550  -ILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSST 608
             +L GL   + VT+  G  L L   + G+PPP+  W + +KA+              ++ 
Sbjct: 1573 RVLGGL--PDVVTIQEGKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAY 1630

Query: 609  LVIDIAERDDSGVYHINLKNEAGEAHASIKVKV 641
              I+     DSG Y + +KN+ G   +   V V
Sbjct: 1631 FTINGVSTADSGKYGLVVKNKYGSETSDFTVSV 1663



 Score = 51.6 bits (122), Expect = 4e-06
 Identities = 38/169 (22%), Positives = 76/169 (44%), Gaps = 11/169 (6%)

Query: 875  RPELTWKKDGAEIDKNQI--NIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASI- 931
            +PE+ W ++G  +  ++    + + E  T+ F     +   G Y ++V++ ++ E  S  
Sbjct: 438  QPEIQWYRNGVPLSPSKWVQTLWSGERATLTFSH-LNKEDEGLYTIRVRMGEYYEQYSAY 496

Query: 932  ------DIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEW 985
                  D +I   P  P  VK  +   + + ++W  P  DG + I GY I K +  +  W
Sbjct: 497  VFVRDADAEIEGAPAAPLDVKCLEANKDYIIISWKQPAVDGGSPILGYFIDKCEVGTDSW 556

Query: 986  FTVIEHYHRTSA-TITELVIGNEYYFRVFSENMCGLSEDATMTKESAVI 1033
                +   + +   +T L+ G  Y FRV + N  G+   + +++  A +
Sbjct: 557  SQCNDTPVKFARFPVTGLIEGRSYIFRVRAVNKMGIGFPSRVSEPVAAL 605



 Score = 45.8 bits (107), Expect = 2e-04
 Identities = 27/78 (34%), Positives = 40/78 (51%), Gaps = 3/78 (3%)

Query: 1070 NATLNCSVRGNPKPKITWMKNKVAI---VDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCC 1126
            N  L+CS+ G P+P++TW KN+V I    +  +Y + S  G+ TLEI      D   Y  
Sbjct: 293  NVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGCDFEDTAQYRA 352

Query: 1127 KAVNDLGTVEIECKLEVK 1144
             A+N  G +     + VK
Sbjct: 353  SAMNVKGELSAYASVVVK 370



 Score = 43.1 bits (100), Expect = 0.002
 Identities = 27/96 (28%), Positives = 42/96 (43%), Gaps = 3/96 (3%)

Query: 939  PGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSA- 997
            PGPP  + + +     V L+W PP   G+  I  Y ++K +  +  W  V       S  
Sbjct: 638  PGPPTDLSVTEATRSYVVLSWKPPGQRGHEGIM-YFVEKCEAGTENWQRVNTELPVKSPR 696

Query: 998  -TITELVIGNEYYFRVFSENMCGLSEDATMTKESAV 1032
              + +L  G  Y FRV   N  G+ E +  T+ + V
Sbjct: 697  FALFDLAEGKSYCFRVRCSNSAGVGEPSEATEVTVV 732



 Score = 40.8 bits (94), Expect = 0.007
 Identities = 35/139 (25%), Positives = 62/139 (44%), Gaps = 4/139 (2%)

Query: 818  KAVNAAGASEPKYYSQPILVKE--IIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPR 875
            K V+ +G +  + Y++   +K+  I E  + R+   L      + G+A+NL     G P 
Sbjct: 1542 KTVDLSGQAYDEAYAEFQRLKQAAIAEKNRARVLGGLPDVVTIQEGKALNLTCNVWGDPP 1601

Query: 876  PELTW-KKDGAEIDKNQINIRNSETDTIIF-IRKAERSHSGKYDLQVKVDKFVETASIDI 933
            PE++W K + A    +  N++     T  F I     + SGKY L VK     ET+   +
Sbjct: 1602 PEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTADSGKYGLVVKNKYGSETSDFTV 1661

Query: 934  QIIDRPGPPQIVKIEDVWG 952
             +       ++  +E + G
Sbjct: 1662 SVFIPEEEARMAALESLKG 1680



 Score = 36.2 bits (82), Expect = 0.18
 Identities = 38/147 (25%), Positives = 61/147 (41%), Gaps = 17/147 (11%)

Query: 498 ESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKIILDGLDAD 557
           E    KVV + +  +L +   L E E         Y+  L    H++  P+ I+      
Sbjct: 237 EKKSRKVVIREKAERLSLRKTLEETE--------TYHAKLNED-HLLHAPEFIIK----P 283

Query: 558 NTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAI--MEGSGRIRTESYPDSSTLVIDIAE 615
            + TV     ++L   I+G P P+  W +    I      G+   ES     TL I+  +
Sbjct: 284 RSHTVWEKENVKLHCSIAGWPEPRVTWYKNQVPINVHANPGKYIIESRYGMHTLEINGCD 343

Query: 616 RDDSGVYHINLKNEAGE--AHASIKVK 640
            +D+  Y  +  N  GE  A+AS+ VK
Sbjct: 344 FEDTAQYRASAMNVKGELSAYASVVVK 370



 Score = 36.2 bits (82), Expect = 0.18
 Identities = 20/68 (29%), Positives = 30/68 (44%), Gaps = 1/68 (1%)

Query: 1068 GYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRM-FSNQGVCTLEIRKPSPYDGGTYCC 1126
            G    L C+V G+P P+++W+KN+ A+  D    + F         I   S  D G Y  
Sbjct: 1587 GKALNLTCNVWGDPPPEVSWLKNEKALASDDHCNLKFEAGRTAYFTINGVSTADSGKYGL 1646

Query: 1127 KAVNDLGT 1134
               N  G+
Sbjct: 1647 VVKNKYGS 1654


>gi|144226847 obscurin-like 1 [Homo sapiens]
          Length = 1896

 Score =  116 bits (291), Expect = 1e-25
 Identities = 96/368 (26%), Positives = 159/368 (43%), Gaps = 12/368 (3%)

Query: 294  RVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGD 353
            RV    EL  P  EV+W K+G+E+  S   + + +   R L +   Q+ D  EY     D
Sbjct: 915  RVVLTCELCRPWAEVRWTKDGEEVVESPALLLQKEDTVRRLVLPAVQLEDSGEYLCEIDD 974

Query: 354  EKCSTELFVREPPIMVTKQLEDTT--AYCGERVELECEVSEDDANVKWFKNGEEIIPGPK 411
            E  S  + V EPP+ +    ++ T  A   E V L CE+S +DA V+W+K+G E+     
Sbjct: 975  ESASFTVTVTEPPVRIIYPRDEVTLIAVTLECVVLMCELSREDAPVRWYKDGLEV--EES 1032

Query: 412  SRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLT---DQT 468
                +  +G +  L++  A   D  E+        +   ++V   P +I+ P     D  
Sbjct: 1033 EALVLERDGPRCRLVLPAAQPEDGGEFVCDAGDDSAFFTVTVTAPPERIVHPAARSLDLH 1092

Query: 469  VNLGKEICLKCEIS-ENIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYV 527
                  + L+CE++      +W K+GL V+ SD L++  +G    L + +A  ED G+YV
Sbjct: 1093 FGAPGRVELRCEVAPAGSQVRWYKDGLEVEASDALQLGAEGPTRTLTLPHAQPEDAGEYV 1152

Query: 528  FAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRG 587
               +  +  +   V + +PP   L      + + V  G  + L   +S    P  +WS  
Sbjct: 1153 C--ETRHEAITFNVILAEPPVQFLALETTPSPLCVAPGEPVVLSCELSRAGAP-VVWSHN 1209

Query: 588  DKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDP 647
             + + EG G +   +      L I  A    +G+Y        G    S  V+V + P  
Sbjct: 1210 GRPVQEGEG-LELHAEGPRRVLCIQAAGPAHAGLYTCQSGAAPGAPSLSFTVQVAEPPVR 1268

Query: 648  PVAPTVTE 655
             VAP   +
Sbjct: 1269 VVAPEAAQ 1276



 Score =  116 bits (291), Expect = 1e-25
 Identities = 130/532 (24%), Positives = 212/532 (39%), Gaps = 37/532 (6%)

Query: 129  SKAGKHLQLKETFERHSRVYTFEMQIIKAKDNFAGNYRCEVTYKDKFDSCSFDLEVHES- 187
            S  G+ +Q  E  E H+      + I  A    AG Y C+        S SF ++V E  
Sbjct: 1207 SHNGRPVQEGEGLELHAEGPRRVLCIQAAGPAHAGLYTCQSGAAPGAPSLSFTVQVAEPP 1266

Query: 188  ------------TGTTPNIDIRSAFKRSGEGQEDAGELDFSGLLKRREVK-QQEEEPQVD 234
                          +TP  D+      SG G       D   L  +  V+ +Q    QV 
Sbjct: 1267 VRVVAPEAAQTRVRSTPGGDLELVVHLSGPGGPVRWYKDGERLASQGRVQLEQAGARQVL 1326

Query: 235  VWELLKNAKPSEYEKIAFQYGITDLRGMLKRLKRMRREEKKSAAFAKILDPAYQVDKGGR 294
              +  ++    EY   A Q           R+  +  EE         L P   V +G  
Sbjct: 1327 RVQGARSGDAGEYLCDAPQDS---------RIFLVSVEEPLLVKLVSELTPL-TVHEGDD 1376

Query: 295  VRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDE 354
              F  E++ P  +V W +NG  + P  +      G  RIL +  CQ+ D     + AG  
Sbjct: 1377 ATFRCEVSPPDADVTWLRNGAVVTPGPQVEMAQNGSSRILTLRGCQLGDAGTVTLRAGST 1436

Query: 355  KCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDA--NVKWFKNGEEIIPGPKS 412
              S  L VRE  ++  ++L+D  A  G+ V LE E     A   V+W + G+ +     S
Sbjct: 1437 ATSARLHVRETELLFLRRLQDVRAEEGQDVCLEVETGRVGAAGAVRWVRGGQPL--PHDS 1494

Query: 413  RYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLG 472
            R  +  +G  H L I G   AD   Y   +   ++ A+LSV  + L++L PL D T++ G
Sbjct: 1495 RLSMAQDGHIHRLFIHGVILADQGTYGCESHHDRTLARLSVRPRQLRVLRPLEDVTISEG 1554

Query: 473  KEICLKCEIS-ENIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPD 531
                 + E+S E + G+W + G+ +    +  +   G  H+LV+      D G   F  D
Sbjct: 1555 GSATFQLELSQEGVTGEWARGGVQLYPGPKCHIHSDGHRHRLVLNGLGLADSGCVSFTAD 1614

Query: 532  AYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAI 591
              ++   A++ V + P  I+ G    + + V  G+    E  +S +      W +   A+
Sbjct: 1615 --SLRCAARLIVREVPVTIVRG---PHDLEVTEGDTATFECELS-QALADVTWEKDGNAL 1668

Query: 592  MEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKN-EAGEAHASIKVKVV 642
               S R+R ++      L +      D+G Y   +    AG    +++ + V
Sbjct: 1669 TP-SPRLRLQALGTRRLLQLRRCGPSDAGTYSCAVGTARAGPVRLTVRERTV 1719



 Score =  113 bits (283), Expect = 9e-25
 Identities = 83/342 (24%), Positives = 146/342 (42%), Gaps = 22/342 (6%)

Query: 289  VDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYY 348
            + +GG   F +EL+   +  +W + G ++ P  K      G +  L +N   + D     
Sbjct: 1551 ISEGGSATFQLELSQEGVTGEWARGGVQLYPGPKCHIHSDGHRHRLVLNGLGLADSGCVS 1610

Query: 349  VTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIP 408
             TA   +C+  L VRE P+ + +   D     G+    ECE+S+  A+V W K+G  + P
Sbjct: 1611 FTADSLRCAARLIVREVPVTIVRGPHDLEVTEGDTATFECELSQALADVTWEKDGNALTP 1670

Query: 409  GPKSRYRIRVEGKKHILIIEGATKADAAEYS-VMTTGGQSSAKLSVDLKPLKILTPLTDQ 467
             P  R R++  G + +L +     +DA  YS  + T      +L+V  + + +L+ L   
Sbjct: 1671 SP--RLRLQALGTRRLLQLRRCGPSDAGTYSCAVGTARAGPVRLTVRERTVAVLSELRSV 1728

Query: 468  TVNLGKEICLKCEISE-NIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDY 526
            +   G     +C +SE    G+W   G P++   R+++  +G+ H LV++    ED G+ 
Sbjct: 1729 SAREGDGATFECTVSEVETTGRWELGGRPLRPGARVRIRQEGKKHILVLSELRAEDAGEV 1788

Query: 527  VFAPDAYNVTLPAKVHVI------DPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPP 580
             F           +V  +       PP+            TV+ G +  LE+ +S     
Sbjct: 1789 RFQAGPAQSLALLEVEALPLQMCRHPPR----------EKTVLVGRRAVLEVTVS-RSGG 1837

Query: 581  KAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVY 622
               W R    +  G  +    S+  + +LVI     +D G Y
Sbjct: 1838 HVCWLREGAELCPGD-KYEMRSHGPTHSLVIHDVRPEDQGTY 1878



 Score =  112 bits (280), Expect = 2e-24
 Identities = 75/243 (30%), Positives = 115/243 (47%), Gaps = 7/243 (2%)

Query: 288  QVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEY 347
            +V +G    F  EL+    +V W K+G  + PS +   +  G +R+L +  C  +D   Y
Sbjct: 1639 EVTEGDTATFECELSQALADVTWEKDGNALTPSPRLRLQALGTRRLLQLRRCGPSDAGTY 1698

Query: 348  YVTAGDEKCS-TELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEI 406
                G  +     L VRE  + V  +L   +A  G+    EC VSE +   +W   G  +
Sbjct: 1699 SCAVGTARAGPVRLTVRERTVAVLSELRSVSAREGDGATFECTVSEVETTGRWELGGRPL 1758

Query: 407  IPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILT-PLT 465
             PG  +R RIR EGKKHIL++      DA E        QS A L V+  PL++   P  
Sbjct: 1759 RPG--ARVRIRQEGKKHILVLSELRAEDAGEVRFQAGPAQSLALLEVEALPLQMCRHPPR 1816

Query: 466  DQTVNLGKEICLKCEISENIPGK--WTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDE 523
            ++TV +G+   L+  +S +  G   W + G  +   D+ ++   G  H LVI +   ED+
Sbjct: 1817 EKTVLVGRRAVLEVTVSRS-GGHVCWLREGAELCPGDKYEMRSHGPTHSLVIHDVRPEDQ 1875

Query: 524  GDY 526
            G Y
Sbjct: 1876 GTY 1878



 Score =  108 bits (270), Expect = 3e-23
 Identities = 92/328 (28%), Positives = 155/328 (47%), Gaps = 11/328 (3%)

Query: 308  VKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTELFVREPP- 366
            V+WYK+GQE+  S   + E++G  R L +   Q +D  E+   AGDE     + + +   
Sbjct: 838  VRWYKDGQEVEESDFVVLENEGPHRRLVLPATQPSDGGEFQCVAGDECAYFTVTITDVSS 897

Query: 367  -IMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHIL 425
             I+         A   ERV L CE+    A V+W K+GEE++  P     ++ E     L
Sbjct: 898  WIVYPSGKVYVAAVRLERVVLTCELCRPWAEVRWTKDGEEVVESP--ALLLQKEDTVRRL 955

Query: 426  IIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGKEIC--LKCEIS- 482
            ++      D+ EY        +S  ++V   P++I+ P  + T+      C  L CE+S 
Sbjct: 956  VLPAVQLEDSGEYLCEIDDESASFTVTVTEPPVRIIYPRDEVTLIAVTLECVVLMCELSR 1015

Query: 483  ENIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAKVH 542
            E+ P +W K+GL V+ES+ L +   G   +LV+  A  ED G++V   DA + +    V 
Sbjct: 1016 EDAPVRWYKDGLEVEESEALVLERDGPRCRLVLPAAQPEDGGEFVC--DAGDDSAFFTVT 1073

Query: 543  VIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTES 602
            V  PP+ I+    A  ++ +  G   R+E+     P    +    D   +E S  ++  +
Sbjct: 1074 VTAPPERIVH--PAARSLDLHFGAPGRVELRCEVAPAGSQVRWYKDGLEVEASDALQLGA 1131

Query: 603  YPDSSTLVIDIAERDDSGVYHINLKNEA 630
               + TL +  A+ +D+G Y    ++EA
Sbjct: 1132 EGPTRTLTLPHAQPEDAGEYVCETRHEA 1159



 Score = 87.0 bits (214), Expect = 9e-17
 Identities = 86/365 (23%), Positives = 149/365 (40%), Gaps = 20/365 (5%)

Query: 294  RVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGD 353
            RV    EL+       WYK+GQ++  S   + +  G +  L +   ++ D  E+      
Sbjct: 733  RVVLTCELSRVDFPATWYKDGQKVEESELLVVKMDGRKHRLILPEAKVQDSGEFECRTEG 792

Query: 354  EKCSTELFVREPPIMVTKQLED--TTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPK 411
                  + V++PP+ +    E     A   E V L CEV  +DA V+W+K+G+E+     
Sbjct: 793  VSAFFGVTVQDPPVHIVDPREHVFVHAITSECVMLACEVDREDAPVRWYKDGQEV--EES 850

Query: 412  SRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNL 471
                +  EG    L++     +D  E+  +   G   A  +V +  +          V +
Sbjct: 851  DFVVLENEGPHRRLVLPATQPSDGGEFQCV--AGDECAYFTVTITDVSSWIVYPSGKVYV 908

Query: 472  G----KEICLKCEISEN-IPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDY 526
                 + + L CE+       +WTK+G  V ES  L +  +  + +LV+     ED G+Y
Sbjct: 909  AAVRLERVVLTCELCRPWAEVRWTKDGEEVVESPALLLQKEDTVRRLVLPAVQLEDSGEY 968

Query: 527  VFAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSR 586
            +   D  + +    V V +PP  I+   D + T+  +    + L   +S E  P   W +
Sbjct: 969  LCEIDDESASF--TVTVTEPPVRIIYPRD-EVTLIAVTLECVVLMCELSREDAP-VRWYK 1024

Query: 587  GDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPD 646
                + E    +     P    LV+  A+ +D G +      +AG+  A   V V   P+
Sbjct: 1025 DGLEVEESEALVLERDGP-RCRLVLPAAQPEDGGEFVC----DAGDDSAFFTVTVTAPPE 1079

Query: 647  PPVAP 651
              V P
Sbjct: 1080 RIVHP 1084



 Score = 86.7 bits (213), Expect = 1e-16
 Identities = 85/358 (23%), Positives = 145/358 (40%), Gaps = 21/358 (5%)

Query: 293  GRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAG 352
            GRV    E+A    +V+WYK+G E+  S       +G  R L + + Q  D  EY     
Sbjct: 1097 GRVELRCEVAPAGSQVRWYKDGLEVEASDALQLGAEGPTRTLTLPHAQPEDAGEYVCETR 1156

Query: 353  DEKCSTELFVREPPIMVTKQLEDTTAYC---GERVELECEVSEDDANVKWFKNGEEIIPG 409
             E  +  + + EPP+         +  C   GE V L CE+S   A V W  NG  +  G
Sbjct: 1157 HEAITFNVILAEPPVQFLALETTPSPLCVAPGEPVVLSCELSRAGAPVVWSHNGRPVQEG 1216

Query: 410  PKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLK----PLKILTPLT 465
                  +  EG + +L I+ A  A A  Y+  +     +  LS  ++    P++++ P  
Sbjct: 1217 --EGLELHAEGPRRVLCIQAAGPAHAGLYTCQSGAAPGAPSLSFTVQVAEPPVRVVAPEA 1274

Query: 466  DQT---VNLGKEICLKCEIS-ENIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTE 521
             QT      G ++ L   +S    P +W K+G  +    R+++   G    L +  A + 
Sbjct: 1275 AQTRVRSTPGGDLELVVHLSGPGGPVRWYKDGERLASQGRVQLEQAGARQVLRVQGARSG 1334

Query: 522  DEGDYVF-APDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPP 580
            D G+Y+  AP    + L   V V +P  +++  +     +TV  G+       +S  P  
Sbjct: 1335 DAGEYLCDAPQDSRIFL---VSVEEP--LLVKLVSELTPLTVHEGDDATFRCEVS-PPDA 1388

Query: 581  KAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIK 638
               W R    +  G  ++       S  L +   +  D+G   +   + A  A   ++
Sbjct: 1389 DVTWLRNGAVVTPGP-QVEMAQNGSSRILTLRGCQLGDAGTVTLRAGSTATSARLHVR 1445



 Score = 84.7 bits (208), Expect = 5e-16
 Identities = 80/305 (26%), Positives = 126/305 (41%), Gaps = 32/305 (10%)

Query: 365 PPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEI--------IPGPKSRYRI 416
           P   +   LED   Y GE      ++S       WF NGEE+        +     RYRI
Sbjct: 614 PTARLVAGLEDVQVYDGEDAVFSLDLSTIIQGT-WFLNGEELKSNEPEGQVEPGALRYRI 672

Query: 417 RVEGKKHILIIEGATKADA-AEYSVMTTGGQSSAKLSVDLKPLKILTPL--TDQTVNLGK 473
             +G +H LI+      D+ A       G Q SA L++   P+ IL+P      T    +
Sbjct: 673 EQKGLQHRLILHAVKHQDSGALVGFSCPGVQDSAALTIQESPVHILSPQDRVSLTFTTSE 732

Query: 474 EICLKCEISE-NIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDA 532
            + L CE+S  + P  W K+G  V+ES+ L V   GR H+L++  A  +D G++    + 
Sbjct: 733 RVVLTCELSRVDFPATWYKDGQKVEESELLVVKMDGRKHRLILPEAKVQDSGEFECRTEG 792

Query: 533 ----YNVTL-PAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRG 587
               + VT+    VH++DP + +         V  I    + L   +  E  P   +  G
Sbjct: 793 VSAFFGVTVQDPPVHIVDPREHVF--------VHAITSECVMLACEVDREDAPVRWYKDG 844

Query: 588 DKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDP 647
            +  +E S  +  E+      LV+   +  D G +       AG+  A   V + D    
Sbjct: 845 QE--VEESDFVVLENEGPHRRLVLPATQPSDGGEFQC----VAGDECAYFTVTITDVSSW 898

Query: 648 PVAPT 652
            V P+
Sbjct: 899 IVYPS 903



 Score = 63.2 bits (152), Expect = 1e-09
 Identities = 63/257 (24%), Positives = 108/257 (42%), Gaps = 15/257 (5%)

Query: 281 KILDPAYQVDKGGRVRF-VVELADPKLEVKWYKNGQEIRPSTKYI-FEHKGCQRILFINN 338
           K     + V++G   +F    +  P+ E++W+  G+ + P  + + +  +    +L +  
Sbjct: 249 KCAPKTFWVNEGKHAKFRCYVMGKPEPEIEWHWEGRPLLPDRRRLMYRDRDGGFVLKVLY 308

Query: 339 CQMTDDSEYYV----TAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDD 394
           CQ  D   Y      +AG    + +L V+EP +  T+ L+D          LEC+V    
Sbjct: 309 CQAKDRGLYVCAARNSAGQTLSAVQLHVKEPRLRFTRPLQDVEGREHGIAVLECKVPNSR 368

Query: 395 ANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGG-QSSAKLSV 453
               WF+  + ++P  K  Y    EG    LII      D   Y     G  ++ A ++V
Sbjct: 369 IPTAWFREDQRLLPCRK--YEQIEEGTVRRLIIHRLKADDDGIYLCEMRGRVRTVANVTV 426

Query: 454 DLKPLKILTPLTDQTVNLGKEICLKCEISE-NIPGKWTKNGLPVQESDRLKVVHKGRIHK 512
               LK L    D  V  G+   L  E  E  + G+W+++G   +E   +     G +H 
Sbjct: 427 KGPILKRLPRKLD--VLEGENAVLLVETLEAGVEGRWSRDG---EELPVICQSSSGHMHA 481

Query: 513 LVIANALTEDEGDYVFA 529
           LV+     ED G+  F+
Sbjct: 482 LVLPGVTREDAGEVTFS 498



 Score = 58.2 bits (139), Expect = 5e-08
 Identities = 71/325 (21%), Positives = 131/325 (40%), Gaps = 31/325 (9%)

Query: 381 GERVELECEV-SEDDANVKWFKNGEEIIPGPKS-RYRIRVEGKKHILIIEGATKADAAEY 438
           G+  +  C V  + +  ++W   G  ++P  +   YR R  G   +L +      D   Y
Sbjct: 260 GKHAKFRCYVMGKPEPEIEWHWEGRPLLPDRRRLMYRDRDGG--FVLKVLYCQAKDRGLY 317

Query: 439 --SVMTTGGQ--SSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCEI-SENIPGKWTKNG 493
             +   + GQ  S+ +L V    L+   PL D          L+C++ +  IP  W +  
Sbjct: 318 VCAARNSAGQTLSAVQLHVKEPRLRFTRPLQDVEGREHGIAVLECKVPNSRIPTAWFRED 377

Query: 494 LPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVF-----APDAYNVTLPAKVHVIDPPK 548
             +    + + + +G + +L+I     +D+G Y+           NVT+   +    P K
Sbjct: 378 QRLLPCRKYEQIEEGTVRRLIIHRLKADDDGIYLCEMRGRVRTVANVTVKGPILKRLPRK 437

Query: 549 IILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSST 608
             LD L+ +N V ++      LE  + G       WSR  + +      I   S      
Sbjct: 438 --LDVLEGENAVLLVE----TLEAGVEGR------WSRDGEELPV----ICQSSSGHMHA 481

Query: 609 LVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPP 668
           LV+    R+D+G    +L N        +K      P PP+   + +   +  ++ W+PP
Sbjct: 482 LVLPGVTREDAGEVTFSLGNSRTTTLLRVKCVKHSPPGPPILAEMFKGHKNTVLLTWKPP 541

Query: 669 AYDGGSPILGYFIERKKKQSSRWMR 693
                +P + Y +ER++  S  W++
Sbjct: 542 EPAPETPFI-YRLERQEVGSEDWIQ 565



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 31/94 (32%), Positives = 51/94 (54%), Gaps = 3/94 (3%)

Query: 560 VTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDS 619
           V V++G +  L+  + GEPPP  +W +G +  +  S R+   +      L++  A   D+
Sbjct: 21  VRVVSGAEAELKCVVLGEPPPVVVWEKGGQQ-LAASERLSFPADGAEHGLLLTAALPTDA 79

Query: 620 GVYHINLKNEAGEAHASIKVKVVDFP--DPPVAP 651
           GVY    +N AGEA+A+  V V++ P  DP + P
Sbjct: 80  GVYVCRARNAAGEAYAAAAVTVLEPPASDPELQP 113



 Score = 44.3 bits (103), Expect = 7e-04
 Identities = 36/155 (23%), Positives = 64/155 (41%), Gaps = 8/155 (5%)

Query: 300 ELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYV-TAGDEKCST 358
           ++ + ++   W++  Q + P  KY    +G  R L I+  +  DD  Y     G  +   
Sbjct: 363 KVPNSRIPTAWFREDQRLLPCRKYEQIEEGTVRRLIIHRLKADDDGIYLCEMRGRVRTVA 422

Query: 359 ELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSRYRIRV 418
            + V+ P +    +  D     GE   L  E  E     +W ++GEE+    +S      
Sbjct: 423 NVTVKGPILKRLPRKLDVLE--GENAVLLVETLEAGVEGRWSRDGEELPVICQSS----- 475

Query: 419 EGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSV 453
            G  H L++ G T+ DA E +      +++  L V
Sbjct: 476 SGHMHALVLPGVTREDAGEVTFSLGNSRTTTLLRV 510



 Score = 43.5 bits (101), Expect = 0.001
 Identities = 70/314 (22%), Positives = 114/314 (36%), Gaps = 56/314 (17%)

Query: 381 GERVELECEV-SEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEY- 438
           G   EL+C V  E    V W K G+++      R     +G +H L++  A   DA  Y 
Sbjct: 26  GAEAELKCVVLGEPPPVVVWEKGGQQL--AASERLSFPADGAEHGLLLTAALPTDAGVYV 83

Query: 439 -SVMTTGGQSSAKLSV----------DLKPLK--------------ILTPLTDQTVNLGK 473
                  G++ A  +V          +L+P +               LT    Q V  G 
Sbjct: 84  CRARNAAGEAYAAAAVTVLEPPASDPELQPAERPLPSPGSGEGAPVFLTGPRSQWVLRGA 143

Query: 474 EICLKCEISENIPGK---WTKNGLPVQE--SDRLKVVHKGRIHK-------LVIANALTE 521
           E+ L C     +P     W K+G+ + E        +  GR          L I  A   
Sbjct: 144 EVVLTCRAG-GLPEPTLYWEKDGMALDEVWDSSHFALQPGRAEDGPGASLALRILAARLP 202

Query: 522 DEGDYV-FAPDAYN---------VTLPAKVHVIDP---PKIILDGLD-ADNTVTVIAGNK 567
           D G YV  A +A+          V  P +    DP   P  +++ L  A  T  V  G  
Sbjct: 203 DSGVYVCHARNAHGHAQAGALLQVHQPPESPPADPDEAPAPVVEPLKCAPKTFWVNEGKH 262

Query: 568 LRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLK 627
            +    + G+P P+  W    + ++    R+          L +   +  D G+Y    +
Sbjct: 263 AKFRCYVMGKPEPEIEWHWEGRPLLPDRRRLMYRDRDGGFVLKVLYCQAKDRGLYVCAAR 322

Query: 628 NEAGEAHASIKVKV 641
           N AG+  +++++ V
Sbjct: 323 NSAGQTLSAVQLHV 336



 Score = 38.1 bits (87), Expect = 0.048
 Identities = 24/78 (30%), Positives = 35/78 (44%), Gaps = 1/78 (1%)

Query: 1068 GYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQ-GVCTLEIRKPSPYDGGTYCC 1126
            G +A   C V G P+P+I W      ++ D R  M+ ++ G   L++      D G Y C
Sbjct: 260  GKHAKFRCYVMGKPEPEIEWHWEGRPLLPDRRRLMYRDRDGGFVLKVLYCQAKDRGLYVC 319

Query: 1127 KAVNDLGTVEIECKLEVK 1144
             A N  G      +L VK
Sbjct: 320  AARNSAGQTLSAVQLHVK 337



 Score = 37.7 bits (86), Expect = 0.063
 Identities = 20/68 (29%), Positives = 28/68 (41%)

Query: 1066 IAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYC 1125
            ++G  A L C V G P P + W K    +    R    ++     L +    P D G Y 
Sbjct: 24   VSGAEAELKCVVLGEPPPVVVWEKGGQQLAASERLSFPADGAEHGLLLTAALPTDAGVYV 83

Query: 1126 CKAVNDLG 1133
            C+A N  G
Sbjct: 84   CRARNAAG 91



 Score = 35.4 bits (80), Expect = 0.31
 Identities = 68/342 (19%), Positives = 125/342 (36%), Gaps = 48/342 (14%)

Query: 806  GLPTDAKIFVRVKAVNAAGASEPKYYS--------QPIL--VKEIIEPPKIRIPRHLKQT 855
            GL   A+   RV  + AAG +    Y+         P L    ++ EPP   +     QT
Sbjct: 1218 GLELHAEGPRRVLCIQAAGPAHAGLYTCQSGAAPGAPSLSFTVQVAEPPVRVVAPEAAQT 1277

Query: 856  YIRRV-GEAVNLVIPFQGKPRPELTWKKDGAEI-DKNQINIRNSETDTIIFIRKAERSHS 913
             +R   G  + LV+   G   P + W KDG  +  + ++ +  +    ++ ++ A    +
Sbjct: 1278 RVRSTPGGDLELVVHLSGPGGP-VRWYKDGERLASQGRVQLEQAGARQVLRVQGARSGDA 1336

Query: 914  GKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGY 973
            G+Y      D  +   S++         P +VK+     E   LT      +G+ A    
Sbjct: 1337 GEYLCDAPQDSRIFLVSVE--------EPLLVKLVS---ELTPLT----VHEGDDATFRC 1381

Query: 974  TIQKADKKSMEWFTVIEHYHRTSATIT---ELVIGNEYYFRVFSENMCGLSEDATMTKES 1030
             +   D   + W        R  A +T   ++ +      R+ +   C L +  T+T  +
Sbjct: 1382 EVSPPDA-DVTWL-------RNGAVVTPGPQVEMAQNGSSRILTLRGCQLGDAGTVTLRA 1433

Query: 1031 AVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSV-RGNPKPKITWMK 1089
               A   +++              +F + L +  A  G +  L     R      + W++
Sbjct: 1434 GSTATSARLHVRET--------ELLFLRRLQDVRAEEGQDVCLEVETGRVGAAGAVRWVR 1485

Query: 1090 NKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVND 1131
                +  D R  M  +  +  L I      D GTY C++ +D
Sbjct: 1486 GGQPLPHDSRLSMAQDGHIHRLFIHGVILADQGTYGCESHHD 1527



 Score = 35.0 bits (79), Expect = 0.41
 Identities = 19/59 (32%), Positives = 28/59 (47%), Gaps = 1/59 (1%)

Query: 1068 GYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCC 1126
            G  AT  C +       +TW K+  A+   PR R+ +      L++R+  P D GTY C
Sbjct: 1643 GDTATFECEL-SQALADVTWEKDGNALTPSPRLRLQALGTRRLLQLRRCGPSDAGTYSC 1700



 Score = 34.3 bits (77), Expect = 0.70
 Identities = 15/47 (31%), Positives = 23/47 (48%)

Query: 1085 ITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVND 1131
            + W++    +    +Y M S+    +L I    P D GTYCC+A  D
Sbjct: 1839 VCWLREGAELCPGDKYEMRSHGPTHSLVIHDVRPEDQGTYCCQAGQD 1885



 Score = 32.7 bits (73), Expect = 2.0
 Identities = 21/77 (27%), Positives = 32/77 (41%), Gaps = 5/77 (6%)

Query: 1068 GYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCK 1127
            G +AT  C V   P   +TW++N   +   P+  M  N     L +R     D GT   +
Sbjct: 1374 GDDATFRCEV-SPPDADVTWLRNGAVVTPGPQVEMAQNGSSRILTLRGCQLGDAGTVTLR 1432

Query: 1128 AVNDLGTVEIECKLEVK 1144
            A    G+     +L V+
Sbjct: 1433 A----GSTATSARLHVR 1445



 Score = 32.3 bits (72), Expect = 2.7
 Identities = 21/72 (29%), Positives = 30/72 (41%), Gaps = 4/72 (5%)

Query: 299 VELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYV----TAGDE 354
           V L +P   V W K GQ++  S +  F   G +  L +     TD   Y       AG+ 
Sbjct: 34  VVLGEPPPVVVWEKGGQQLAASERLSFPADGAEHGLLLTAALPTDAGVYVCRARNAAGEA 93

Query: 355 KCSTELFVREPP 366
             +  + V EPP
Sbjct: 94  YAAAAVTVLEPP 105



 Score = 32.3 bits (72), Expect = 2.7
 Identities = 17/55 (30%), Positives = 23/55 (41%)

Query: 308  VKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTELFV 362
            V W + G E+ P  KY     G    L I++ +  D   Y   AG +   T L V
Sbjct: 1839 VCWLREGAELCPGDKYEMRSHGPTHSLVIHDVRPEDQGTYCCQAGQDSTHTRLLV 1893



 Score = 31.2 bits (69), Expect = 5.9
 Identities = 25/100 (25%), Positives = 38/100 (38%), Gaps = 9/100 (9%)

Query: 1053 APMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQ------ 1106
            AP+F     + + + G    L C   G P+P + W K+ +A+ +      F+ Q      
Sbjct: 127  APVFLTGPRSQWVLRGAEVVLTCRAGGLPEPTLYWEKDGMALDEVWDSSHFALQPGRAED 186

Query: 1107 ---GVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1143
                   L I      D G Y C A N  G  +    L+V
Sbjct: 187  GPGASLALRILAARLPDSGVYVCHARNAHGHAQAGALLQV 226


>gi|20127422 Down syndrome cell adhesion molecule isoform CHD2-42
            precursor [Homo sapiens]
          Length = 2012

 Score =  116 bits (290), Expect = 1e-25
 Identities = 212/926 (22%), Positives = 346/926 (37%), Gaps = 162/926 (17%)

Query: 304  PKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMT-DDSEYYVTAGDEKC------ 356
            P   +KWYKN      S    F H+   ++ F NN  +   D +  V  G+  C      
Sbjct: 531  PYYSIKWYKN------SNLLPFNHR---QVAFENNGTLKLSDVQKEVDEGEYTCNVLVQP 581

Query: 357  ------STELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDA--NVKWFKNGEEIIP 408
                  S  + V+ PP +  +  E      G+RV + C V   D    + W K+G  I P
Sbjct: 582  QLSTSQSVHVTVKVPPFI--QPFEFPRFSIGQRVFIPCVVVSGDLPITITWQKDGRPI-P 638

Query: 409  GPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGG------------QSSAKLSVDLK 456
            G      + ++       I+  +    +  S+M  G             +  ++L V + 
Sbjct: 639  GSLG---VTIDN------IDFTSSLRISNLSLMHNGNYTCIARNEAAAVEHQSQLIVRVP 689

Query: 457  PLKILTPLTDQTVNLGKEICLKCEIS----ENIPGKWTKNG-----LPVQESDRLKVVHK 507
            P  ++ P  DQ    GK + L C         I  K++K        P+  + R++V+  
Sbjct: 690  PKFVVQP-RDQDGIYGKAVILNCSAEGYPVPTIVWKFSKGAGVPQFQPIALNGRIQVLSN 748

Query: 508  GRIHKLVIANALTEDEGDY-------VFAPDAYNVTLPAKVHVIDPPKIILDGLDADNTV 560
            G    L+I + + ED G Y       V A  + ++ L  K+     P +I       NT 
Sbjct: 749  G---SLLIKHVVEEDSGYYLCKVSNDVGADVSKSMYLTVKI-----PAMITS---YPNTT 797

Query: 561  TVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGR--IRTESYPDS--STLVIDIAER 616
                G K  +     GE P    W + D+ I     R  + T+   +   STL I    R
Sbjct: 798  LATQGQKKEMSCTAHGEKPIIVRWEKEDRIINPEMARYLVSTKEVGEEVISTLQILPTVR 857

Query: 617  DDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPI 676
            +DSG +  +  N  GE    I++ V + PDPP    + +V      + W    +DG SPI
Sbjct: 858  EDSGFFSCHAINSYGEDRGIIQLTVQEPPDPPEI-EIKDVKARTITLRW-TMGFDGNSPI 915

Query: 677  LGYFIERKKKQSS-----RWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPS 731
             GY IE K K  S     R   ++  L   T  +   +     Y +R++A N IG S+PS
Sbjct: 916  TGYDIECKNKSDSWDSAQRTKDVSPQLNSATIID---IHPSSTYSIRMYAKNRIGKSEPS 972

Query: 732  MP-SRPFVPLAVTSPPTLLTVDSVTDTTVTMRWR-PPDHIGAAGLDGYVL---EYCFEGT 786
               +      A   PP  + ++ ++  ++ + W+ P  H+    + GY +   EY   G 
Sbjct: 973  NELTITADEAAPDGPPQEVHLEPISSQSIRVTWKAPKKHLQNGIIRGYQIGYREYSTGGN 1032

Query: 787  EDWIVANKDLI-DKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPK 845
              + + + D   D   +T+  L    +  + V+A N AG       SQ I+   + + P 
Sbjct: 1033 FQFNIISVDTSGDSEVYTLDNLNKFTQYGLVVQACNRAGTGPS---SQEIITTTLEDVPS 1089

Query: 846  ---------IRIPRHLKQTYIRRVGEAVNLVIP----------FQGK--PRPELTWKKDG 884
                        P  +  ++     EA+N ++             G+      +T  +  
Sbjct: 1090 YPPENVQAIATSPESISISWSTLSKEALNGILQGFRVIYWANLMDGELGEIKNITTTQPS 1149

Query: 885  AEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQI 944
             E+D  +    N     + F R  +   S +   + K D               PGPP  
Sbjct: 1150 LELDGLE-KYTNYSIQVLAFTRAGDGVRSEQIFTRTKEDV--------------PGPPAG 1194

Query: 945  VKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVI 1004
            VK        V ++W PP    N  I  YT+      S  + TVI  +  +  +      
Sbjct: 1195 VKAAAASASMVFVSWLPPL-KLNGIIRKYTV----FCSHPYPTVISEFEASPDS------ 1243

Query: 1005 GNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTY 1064
                    FS  +  LS +   +     +   G+   + +      ++AP        T 
Sbjct: 1244 --------FSYRIPNLSRNRQYSVWVVAVTSAGRGNSSEIITVEPLAKAPARILTFSGTV 1295

Query: 1065 AIAGY-NATLNCSVRGNPKPKITWMKNK----VAIVDDPRYRMFSNQGVCTLEIRKPSPY 1119
                  +  L C   G+P P + WMK+       +  D R  +FSN    +  IR     
Sbjct: 1296 TTPWMKDIVLPCKAVGDPSPAVKWMKDSNGTPSLVTIDGRRSIFSNG---SFIIRTVKAE 1352

Query: 1120 DGGTYCCKAVNDLGTVEIECKLEVKV 1145
            D G Y C A N+ G+ EI   L+V+V
Sbjct: 1353 DSGYYSCIANNNWGSDEIILNLQVQV 1378



 Score = 83.6 bits (205), Expect = 1e-15
 Identities = 167/786 (21%), Positives = 300/786 (38%), Gaps = 97/786 (12%)

Query: 301  LADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTA----GDEKC 356
            L  P+ + +W K+   +  S ++     G    L I N + +D   Y        G  K 
Sbjct: 249  LGHPEPDYRWLKDNMPLELSGRFQKTVTG----LLIENIRPSDSGSYVCEVSNRYGTAKV 304

Query: 357  STELFVREPPIMVTKQLEDTTAYCGERVELECEVS-EDDANVKWFKNGEEIIPGPKSRYR 415
               L+V++P +  T       +  G +V L C V+  +D  + W++NGE + PG      
Sbjct: 305  IGRLYVKQP-LKATISPRKVKSSVGSQVSLSCSVTGTEDQELSWYRNGEILNPGK----N 359

Query: 416  IRVEGKKH-ILIIEGATKADAAEYSVMTTGGQSSAKLSVDL----KPLKILTPLTDQTVN 470
            +R+ G  H  LI++   K+D   Y       + SA+  V +       KI++  +++ V+
Sbjct: 360  VRITGINHENLIMDHMVKSDGGAYQCFVRKDKLSAQDYVQVVLEDGTPKIISAFSEKVVS 419

Query: 471  LGKEICLKCEISEN-IPG-KWTKNGLPVQE--SDRLK--VVHKGR-IHKLVIANALTEDE 523
              + + L C +    +P   WT +  P+ +  S R+   +  +G  +  L I+++   D 
Sbjct: 420  PAEPVSLMCNVKGTPLPTITWTLDDDPILKGGSHRISQMITSEGNVVSYLNISSSQVRDG 479

Query: 524  GDY-VFAPDAYNVTL-PAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPK 581
            G Y   A ++  V L  A+++V  P  I          +T IAG    +   + G P   
Sbjct: 480  GVYRCTANNSAGVVLYQARINVRGPASI-----RPMKNITAIAGRDTYIHCRVIGYPYYS 534

Query: 582  AMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINL-----KNEAGEAHAS 636
              W +    +     ++  E+  + +  + D+ +  D G Y  N+      + +   H +
Sbjct: 535  IKWYKNSNLLPFNHRQVAFEN--NGTLKLSDVQKEVDEGEYTCNVLVQPQLSTSQSVHVT 592

Query: 637  IKV----KVVDFPDPPVA-----PTVTEVGDDWCIMNWEPPAYDGGSPI---LGYFIERK 684
            +KV    +  +FP   +      P V   GD    + W+      G PI   LG  I+  
Sbjct: 593  VKVPPFIQPFEFPRFSIGQRVFIPCVVVSGDLPITITWQ----KDGRPIPGSLGVTIDNI 648

Query: 685  KKQSSRWMRL-NFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVT 743
               SS  +R+ N  L     +      E  A E +   +  +    P    +P     + 
Sbjct: 649  DFTSS--LRISNLSLMHNGNYTCIARNEAAAVEHQSQLIVRV---PPKFVVQPRDQDGIY 703

Query: 744  SPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFT 803
                +L   +      T+ W+     G        L    +     +++N  L+      
Sbjct: 704  GKAVILNCSAEGYPVPTIVWKFSKGAGVPQFQPIALNGRIQ-----VLSNGSLL------ 752

Query: 804  ITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEA 863
            I  +  +   +   K  N  GA   K     + +  +I             T +   G+ 
Sbjct: 753  IKHVVEEDSGYYLCKVSNDVGADVSKSMYLTVKIPAMI--------TSYPNTTLATQGQK 804

Query: 864  VNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNS------ETDTIIFIRKAERSHSGKYD 917
              +     G+    + W+K+   I+        S      E  + + I    R  SG + 
Sbjct: 805  KEMSCTAHGEKPIIVRWEKEDRIINPEMARYLVSTKEVGEEVISTLQILPTVREDSGFFS 864

Query: 918  LQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQ- 976
                     +   I + + + P PP+I +I+DV    + L WT    DGN+ ITGY I+ 
Sbjct: 865  CHAINSYGEDRGIIQLTVQEPPDPPEI-EIKDVKARTITLRWT-MGFDGNSPITGYDIEC 922

Query: 977  --KADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSE---DATMTKESA 1031
              K+D       T        SATI ++   + Y  R++++N  G SE   + T+T + A
Sbjct: 923  KNKSDSWDSAQRTKDVSPQLNSATIIDIHPSSTYSIRMYAKNRIGKSEPSNELTITADEA 982

Query: 1032 VIARDG 1037
              A DG
Sbjct: 983  --APDG 986



 Score = 54.3 bits (129), Expect = 7e-07
 Identities = 72/333 (21%), Positives = 128/333 (38%), Gaps = 33/333 (9%)

Query: 702  TTFEPKKMIEGVA----YEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDT 757
            TT +P   ++G+     Y +++ A    G    S          V  PP  +   + + +
Sbjct: 1144 TTTQPSLELDGLEKYTNYSIQVLAFTRAGDGVRSEQIFTRTKEDVPGPPAGVKAAAASAS 1203

Query: 758  TVTMRWRPPDHIGAAGLDGYVLEY---CFEGTEDWIVANKDLIDKTKFTITGLPTDAKIF 814
             V + W PP       L+G + +Y   C       I   +   D   + I  L  + +  
Sbjct: 1204 MVFVSWLPP-----LKLNGIIRKYTVFCSHPYPTVISEFEASPDSFSYRIPNLSRNRQYS 1258

Query: 815  VRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQ--G 872
            V V AV +AG       S+ I V+ + + P     R L  +         ++V+P +  G
Sbjct: 1259 VWVVAVTSAGRGNS---SEIITVEPLAKAPA----RILTFSGTVTTPWMKDIVLPCKAVG 1311

Query: 873  KPRPELTWKKDG------AEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFV 926
             P P + W KD         ID  +    N        IR  +   SG Y      +   
Sbjct: 1312 DPSPAVKWMKDSNGTPSLVTIDGRRSIFSNGS----FIIRTVKAEDSGYYSCIANNNWGS 1367

Query: 927  ETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWF 986
            +   +++Q+   P  P++  +      ++ L+W P  D+G ++I GY +Q ++  S +W 
Sbjct: 1368 DEIILNLQVQVPPDQPRLT-VSKTTSSSITLSWLPG-DNGGSSIRGYILQYSEDNSEQWG 1425

Query: 987  TVIEHYHRTSATITELVIGNEYYFRVFSENMCG 1019
            +        S  +  L  G  Y F + ++N  G
Sbjct: 1426 SFPISPSERSYRLENLKCGTWYKFTLTAQNGVG 1458



 Score = 54.3 bits (129), Expect = 7e-07
 Identities = 64/284 (22%), Positives = 109/284 (38%), Gaps = 24/284 (8%)

Query: 554  LDADNTVTVIAGNKLRLEIPISGEPPPKAMW---SRGDKAIMEGSGRIRTESYPDSSTLV 610
            L    TVT      + L     G+P P   W   S G  +++   GR    S   + + +
Sbjct: 1289 LTFSGTVTTPWMKDIVLPCKAVGDPSPAVKWMKDSNGTPSLVTIDGR---RSIFSNGSFI 1345

Query: 611  IDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAY 670
            I   + +DSG Y     N  G     + ++V   PD P   TV++       ++W P   
Sbjct: 1346 IRTVKAEDSGYYSCIANNNWGSDEIILNLQVQVPPDQPRL-TVSKTTSSSITLSWLP-GD 1403

Query: 671  DGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKP 730
            +GGS I GY ++  +  S +W         E ++  + +  G  Y+  + A N +G   P
Sbjct: 1404 NGGSSIRGYILQYSEDNSEQWGSFPIS-PSERSYRLENLKCGTWYKFTLTAQNGVG---P 1459

Query: 731  SMPSRPFVPLAVTSPPTLLTVD----SVTDTTVTMR---WRPPDHIGAAGLDGYVLEYCF 783
               S       +   P          S+  T V +    W      G   +  + LEY  
Sbjct: 1460 GRISEIIEAKTLGKEPQFSKEQELFASINTTRVRLNLIGWND----GGCPITSFTLEYRP 1515

Query: 784  EGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASE 827
             GT  W  A +  + K+ + +  L       ++++  N+AG +E
Sbjct: 1516 FGTTVWTTAQRTSLSKS-YILYDLQEATWYELQMRVCNSAGCAE 1558



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 85/367 (23%), Positives = 138/367 (37%), Gaps = 72/367 (19%)

Query: 789  WIVANKDLIDKTKF--TITGL------PTDAKIFVRVKAVNAAGASEP---KYYSQPILV 837
            W+  N  L    +F  T+TGL      P+D+  +V  +  N  G ++     Y  QP+  
Sbjct: 258  WLKDNMPLELSGRFQKTVTGLLIENIRPSDSGSYV-CEVSNRYGTAKVIGRLYVKQPL-- 314

Query: 838  KEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQ-INIRN 896
            K  I P K++            VG  V+L     G    EL+W ++G  ++  + + I  
Sbjct: 315  KATISPRKVK----------SSVGSQVSLSCSVTGTEDQELSWYRNGEILNPGKNVRITG 364

Query: 897  SETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVA 956
               + +I      +S  G Y   V+ DK   +A   +Q++   G P+I+     + E V 
Sbjct: 365  INHENLIMDHMV-KSDGGAYQCFVRKDKL--SAQDYVQVVLEDGTPKIIS---AFSEKVV 418

Query: 957  LTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHY-----HRTSATITELVIGNEYYFR 1011
                P     N       ++     ++ W    +       HR S  IT    GN   + 
Sbjct: 419  SPAEPVSLMCN-------VKGTPLPTITWTLDDDPILKGGSHRISQMITSE--GNVVSYL 469

Query: 1012 VFSENMCGLSEDATMTKESAVIARDGKIYKNP--------VYEDFDFSEAPMFTQPLVNT 1063
              S +                  RDG +Y+          +Y+       P   +P+ N 
Sbjct: 470  NISSSQ----------------VRDGGVYRCTANNSAGVVLYQARINVRGPASIRPMKNI 513

Query: 1064 YAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTL-EIRKPSPYDGG 1122
             AIAG +  ++C V G P   I W KN   +  + R   F N G   L +++K    D G
Sbjct: 514  TAIAGRDTYIHCRVIGYPYYSIKWYKNSNLLPFNHRQVAFENNGTLKLSDVQK--EVDEG 571

Query: 1123 TYCCKAV 1129
             Y C  +
Sbjct: 572  EYTCNVL 578



 Score = 48.9 bits (115), Expect = 3e-05
 Identities = 67/291 (23%), Positives = 116/291 (39%), Gaps = 34/291 (11%)

Query: 861  GEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQV 920
            G+ V L     G P P+  W KD   ++   ++ R  +T T + I     S SG Y  +V
Sbjct: 239  GQRVELPCKALGHPEPDYRWLKDNMPLE---LSGRFQKTVTGLLIENIRPSDSGSYVCEV 295

Query: 921  KVDKFVETASIDIQIIDRPGPPQIV--KIEDVWGENVALTWTPPKDDGNAAITGYTIQKA 978
              +++     I    + +P    I   K++   G  V+L+          ++TG      
Sbjct: 296  S-NRYGTAKVIGRLYVKQPLKATISPRKVKSSVGSQVSLS---------CSVTG-----T 340

Query: 979  DKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGK 1038
            + + + W+   E  +     +    I +E           G +    + K+  + A+D  
Sbjct: 341  EDQELSWYRNGEILN-PGKNVRITGINHENLIMDHMVKSDGGAYQCFVRKDK-LSAQD-- 396

Query: 1039 IYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDP 1098
             Y   V ED        F++ +V+         +L C+V+G P P ITW  +   I+   
Sbjct: 397  -YVQVVLEDGTPKIISAFSEKVVSP----AEPVSLMCNVKGTPLPTITWTLDDDPILKGG 451

Query: 1099 RYR---MFSNQG--VCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVK 1144
             +R   M +++G  V  L I      DGG Y C A N  G V  + ++ V+
Sbjct: 452  SHRISQMITSEGNVVSYLNISSSQVRDGGVYRCTANNSAGVVLYQARINVR 502



 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 27/94 (28%), Positives = 44/94 (46%), Gaps = 4/94 (4%)

Query: 1051 SEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCT 1110
            + AP       +  A+AG    L C   G+P+P   W+K+ + +    R++    + V  
Sbjct: 222  NSAPSILDGFDHRKAMAGQRVELPCKALGHPEPDYRWLKDNMPLELSGRFQ----KTVTG 277

Query: 1111 LEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVK 1144
            L I    P D G+Y C+  N  GT ++  +L VK
Sbjct: 278  LLIENIRPSDSGSYVCEVSNRYGTAKVIGRLYVK 311



 Score = 38.9 bits (89), Expect = 0.028
 Identities = 32/90 (35%), Positives = 40/90 (44%), Gaps = 11/90 (12%)

Query: 1066 IAGYNATLNCSVRGNPKPKITWMKNKVA-------IVDDPRYRMFSNQGVCTLEIRKPSP 1118
            I G    LNCS  G P P I W  +K A       I  + R ++ SN    +L I+    
Sbjct: 702  IYGKAVILNCSAEGYPVPTIVWKFSKGAGVPQFQPIALNGRIQVLSNG---SLLIKHVVE 758

Query: 1119 YDGGTYCCKAVNDLGT-VEIECKLEVKVIA 1147
             D G Y CK  ND+G  V     L VK+ A
Sbjct: 759  EDSGYYLCKVSNDVGADVSKSMYLTVKIPA 788



 Score = 35.0 bits (79), Expect = 0.41
 Identities = 40/180 (22%), Positives = 66/180 (36%), Gaps = 21/180 (11%)

Query: 466 DQTVNLGKEICLKCEISENIPG-----KWTKNGLPVQESDRLKVVHKGRIHKLVIANALT 520
           DQ    G     KC I  ++        W K+ + +    R  +   G ++   + N   
Sbjct: 132 DQKTMRGNVAVFKCIIPSSVEAYITVVSWEKDTVSLVSGSRFLITSTGALYIKDVQN--- 188

Query: 521 EDEGDYVFA-------PDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIP 573
            ++G Y +              +  A++ V DP       LD  +    +AG ++ L   
Sbjct: 189 -EDGLYNYRCITRHRYTGETRQSNSARLFVSDPANSAPSILDGFDHRKAMAGQRVELPCK 247

Query: 574 ISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEA 633
             G P P   W + D   +E SGR +       + L+I+     DSG Y   + N  G A
Sbjct: 248 ALGHPEPDYRWLK-DNMPLELSGRFQ----KTVTGLLIENIRPSDSGSYVCEVSNRYGTA 302



 Score = 33.9 bits (76), Expect = 0.91
 Identities = 28/108 (25%), Positives = 44/108 (40%), Gaps = 5/108 (4%)

Query: 285 PAYQVDKGGRVRFVVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDD 344
           P + + +   +  VV   D  + + W K+G+ I  S     ++      L I+N  +  +
Sbjct: 605 PRFSIGQRVFIPCVVVSGDLPITITWQKDGRPIPGSLGVTIDNIDFTSSLRISNLSLMHN 664

Query: 345 SEYYVTAGDEKCSTE----LFVREPPIMVTKQLEDTTAYCGERVELEC 388
             Y   A +E  + E    L VR PP  V  Q  D     G+ V L C
Sbjct: 665 GNYTCIARNEAAAVEHQSQLIVRVPPKFVV-QPRDQDGIYGKAVILNC 711


>gi|155969693 myomesin family, member 3 [Homo sapiens]
          Length = 1437

 Score =  114 bits (284), Expect = 7e-25
 Identities = 107/438 (24%), Positives = 179/438 (40%), Gaps = 35/438 (7%)

Query: 642  VDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDL-CK 700
            V  P PP     +E+ + + ++ WE P+    +P L Y +E+    S  W  ++ +   +
Sbjct: 498  VTIPSPPTNVHASEIREAYVVLAWEEPSPRDRAP-LTYSLEKSVIGSGTWEAISSESPVR 556

Query: 701  ETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFV---PLAVTSPPTLLTVDSVTDT 757
               F    + +  +Y  R+ A+N  G+S PS PS P     P A   PP  +     T T
Sbjct: 557  SPRFAVLDLEKKKSYVFRVRAMNQYGLSDPSEPSEPIALRGPPATLPPPAQVQAFRDTQT 616

Query: 758  TVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRV 817
            +V++ W P   +    L GY +     GT +W   N   I  T+FT+ GL T  +    V
Sbjct: 617  SVSLTWDP---VKDPELLGYYIYSRKVGTSEWQTVNNKPIQGTRFTVPGLRTGKEYEFCV 673

Query: 818  KAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQ---GKP 874
            ++V+ AG  E    ++PI VK+ +  P    P         +    +    P +   GK 
Sbjct: 674  RSVSEAGVGESSAATEPIRVKQALATPS--APYGFALLNCGKNEMVIGWKPPKRRGGGKI 731

Query: 875  RPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGK-YDLQVKVDKFVETASIDI 933
                  + D  E+D + +N +   T     + K    H G  Y+ + +   +     +  
Sbjct: 732  LGYFLDQHDSEELDWHAVNQQPIPTR----VCKVSDLHEGHFYEFRARAANWAGVGELSA 787

Query: 934  Q---------IIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSME 984
                       + +PGPP  V+  +V   ++ L W PP   G   +TGY +   ++ S +
Sbjct: 788  PSSLFECKEWTMPQPGPPYDVRASEVRATSLVLQWEPPLYMGAGPVTGYHVSFQEEGSEQ 847

Query: 985  WFTVIE-HYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMT-------KESAVIARD 1036
            W  V       T   +++L  G  Y F+V + N  GL + +  T       K  A     
Sbjct: 848  WKPVTPGPISGTHLRVSDLQPGKSYVFQVQAMNSAGLGQPSMPTDPVLLEDKPGAHEIEV 907

Query: 1037 GKIYKNPVYEDFDFSEAP 1054
            G   +  +Y  F+  EAP
Sbjct: 908  GVDEEGFIYLAFEAPEAP 925



 Score =  100 bits (249), Expect = 8e-21
 Identities = 72/301 (23%), Positives = 128/301 (42%), Gaps = 19/301 (6%)

Query: 629 EAGEAHASIKVK-VVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQ 687
           E+  A   I+VK  +  P  P    +   G +  ++ W+PP   GG  ILGYF+++   +
Sbjct: 683 ESSAATEPIRVKQALATPSAPYGFALLNCGKNEMVIGWKPPKRRGGGKILGYFLDQHDSE 742

Query: 688 SSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFV----PLAVT 743
              W  +N         +   + EG  YE R  A N  G+ + S PS  F      +   
Sbjct: 743 ELDWHAVNQQPIPTRVCKVSDLHEGHFYEFRARAANWAGVGELSAPSSLFECKEWTMPQP 802

Query: 744 SPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFT 803
            PP  +    V  T++ ++W PP ++GA  + GY + +  EG+E W       I  T   
Sbjct: 803 GPPYDVRASEVRATSLVLQWEPPLYMGAGPVTGYHVSFQEEGSEQWKPVTPGPISGTHLR 862

Query: 804 ITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEA 863
           ++ L        +V+A+N+AG  +P   + P+L+++     +I +           V E 
Sbjct: 863 VSDLQPGKSYVFQVQAMNSAGLGQPSMPTDPVLLEDKPGAHEIEV----------GVDEE 912

Query: 864 VNLVIPFQGKPRP---ELTWKKD-GAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQ 919
             + + F+    P   E  W KD    +D  ++ I +    + + +++      G Y + 
Sbjct: 913 GFIYLAFEAPEAPDSSEFQWSKDYKGPLDPQRVKIEDKVNKSKVILKEPGLEDLGTYSVI 972

Query: 920 V 920
           V
Sbjct: 973 V 973



 Score =  100 bits (248), Expect = 1e-20
 Identities = 108/491 (21%), Positives = 190/491 (38%), Gaps = 64/491 (13%)

Query: 584  WSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVD 643
            W R D +++  S R +       ++L +    ++D G+Y + + +  G    S  V V D
Sbjct: 306  WFR-DGSLLRSSRRRKILYTDRQASLKVSCTYKEDEGLYMVRVPSPFGPREQSTYVLVRD 364

Query: 644  F-------PDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNF 696
                    P  P+     +V  D  I+ W PP+   G+PI  Y IER + +S  W+  + 
Sbjct: 365  AEAENPGAPGSPLNVRCLDVNRDCLILTWAPPSDTRGNPITAYTIERCQGESGEWIACHE 424

Query: 697  DLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFV------------------ 738
                      + ++EG +Y  R+ A++ +G S PS  S   V                  
Sbjct: 425  APGGTCRCPIQGLVEGQSYRFRVRAISRVGSSVPSKASELVVMGDHDAARRKTEIPFDLG 484

Query: 739  ------------PLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGT 786
                         + + SPPT +    + +  V + W  P     A L  Y LE    G+
Sbjct: 485  NKITISTDAFEDTVTIPSPPTNVHASEIREAYVVLAWEEPSPRDRAPLT-YSLEKSVIGS 543

Query: 787  EDW-IVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPK 845
              W  ++++  +   +F +  L        RV+A+N  G S+P   S+PI ++     P 
Sbjct: 544  GTWEAISSESPVRSPRFAVLDLEKKKSYVFRVRAMNQYGLSDPSEPSEPIALR----GPP 599

Query: 846  IRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFI 905
              +P   +    R    +V+L   +     PEL     G  I   ++     +T     I
Sbjct: 600  ATLPPPAQVQAFRDTQTSVSLT--WDPVKDPELL----GYYIYSRKVGTSEWQTVNNKPI 653

Query: 906  RKAERSHSG-----KYDLQVKV-------DKFVETASIDI-QIIDRPGPPQIVKIEDVWG 952
            +    +  G     +Y+  V+        +    T  I + Q +  P  P    + +   
Sbjct: 654  QGTRFTVPGLRTGKEYEFCVRSVSEAGVGESSAATEPIRVKQALATPSAPYGFALLNCGK 713

Query: 953  ENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTS-ATITELVIGNEYYFR 1011
              + + W PPK  G   I GY + + D + ++W  V +    T    +++L  G+ Y FR
Sbjct: 714  NEMVIGWKPPKRRGGGKILGYFLDQHDSEELDWHAVNQQPIPTRVCKVSDLHEGHFYEFR 773

Query: 1012 VFSENMCGLSE 1022
              + N  G+ E
Sbjct: 774  ARAANWAGVGE 784



 Score = 52.0 bits (123), Expect = 3e-06
 Identities = 33/113 (29%), Positives = 52/113 (46%), Gaps = 8/113 (7%)

Query: 1038 KIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDD 1097
            K+ +     +  +   P F  PL +          L C+V+ +P P++TW KN   I  D
Sbjct: 138  KVQEAKELRELCYGRGPWFWIPLRSHAVWEHTTVLLTCTVQASPPPQVTWYKNDTRI--D 195

Query: 1098 PR------YRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVK 1144
            PR      YR+ +N G+ +LEIR+ +  D  TY  +  N  G      K+ V+
Sbjct: 196  PRLFRAGKYRITNNYGLLSLEIRRCAIEDSATYTVRVKNAHGQASSFAKVLVR 248



 Score = 42.4 bits (98), Expect = 0.003
 Identities = 24/91 (26%), Positives = 41/91 (45%), Gaps = 1/91 (1%)

Query: 558  NTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERD 617
            +  T++    L L   +SG+P P+  W + D+ +     R R E      T+ I+    +
Sbjct: 1342 DVATIMEDKTLCLTCIVSGDPTPEISWLKNDQPVTF-LDRYRMEVRGTEVTITIEKVNSE 1400

Query: 618  DSGVYHINLKNEAGEAHASIKVKVVDFPDPP 648
            DSG Y + +KN+ G     + + V    D P
Sbjct: 1401 DSGRYGVFVKNKYGSETGQVTISVFKHGDEP 1431



 Score = 41.6 bits (96), Expect = 0.004
 Identities = 22/62 (35%), Positives = 30/62 (48%)

Query: 1073 LNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDL 1132
            L C V G+P P+I+W+KN   +    RYRM       T+ I K +  D G Y     N  
Sbjct: 1354 LTCIVSGDPTPEISWLKNDQPVTFLDRYRMEVRGTEVTITIEKVNSEDSGRYGVFVKNKY 1413

Query: 1133 GT 1134
            G+
Sbjct: 1414 GS 1415



 Score = 40.0 bits (92), Expect = 0.013
 Identities = 28/110 (25%), Positives = 48/110 (43%), Gaps = 5/110 (4%)

Query: 840  IIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEI---DKNQINIRN 896
            IIE  + ++ R L         + + L     G P PE++W K+   +   D+ ++ +R 
Sbjct: 1328 IIEKNRAKVVRGLPDVATIMEDKTLCLTCIVSGDPTPEISWLKNDQPVTFLDRYRMEVRG 1387

Query: 897  SETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVK 946
              T+  I I K     SG+Y + VK     ET  + I +      P+ +K
Sbjct: 1388 --TEVTITIEKVNSEDSGRYGVFVKNKYGSETGQVTISVFKHGDEPKELK 1435



 Score = 36.2 bits (82), Expect = 0.18
 Identities = 32/129 (24%), Positives = 52/129 (40%), Gaps = 10/129 (7%)

Query: 906  RKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDD 965
            RK E        + +  D F +T +I       P PP  V   ++    V L W  P   
Sbjct: 475  RKTEIPFDLGNKITISTDAFEDTVTI-------PSPPTNVHASEIREAYVVLAWEEPSPR 527

Query: 966  GNAAITGYTIQKADKKSMEWFTVIEHYHRTSA--TITELVIGNEYYFRVFSENMCGLSED 1023
              A +T Y+++K+   S  W  +       S    + +L     Y FRV + N  GLS+ 
Sbjct: 528  DRAPLT-YSLEKSVIGSGTWEAISSESPVRSPRFAVLDLEKKKSYVFRVRAMNQYGLSDP 586

Query: 1024 ATMTKESAV 1032
            +  ++  A+
Sbjct: 587  SEPSEPIAL 595



 Score = 36.2 bits (82), Expect = 0.18
 Identities = 35/148 (23%), Positives = 60/148 (40%), Gaps = 10/148 (6%)

Query: 411  KSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTD-QTV 469
            K +Y + +   K +  +       A E   M    +      ++    K++  L D  T+
Sbjct: 1288 KGKYTLEIAAGKEVRQLSTDLSGQAFE-DAMAEHQRLKTLAIIEKNRAKVVRGLPDVATI 1346

Query: 470  NLGKEICLKCEISENIPGK--WTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDY- 526
               K +CL C +S +   +  W KN  PV   DR ++  +G    + I    +ED G Y 
Sbjct: 1347 MEDKTLCLTCIVSGDPTPEISWLKNDQPVTFLDRYRMEVRGTEVTITIEKVNSEDSGRYG 1406

Query: 527  VFAPDAY-----NVTLPAKVHVIDPPKI 549
            VF  + Y      VT+    H  +P ++
Sbjct: 1407 VFVKNKYGSETGQVTISVFKHGDEPKEL 1434



 Score = 33.9 bits (76), Expect = 0.91
 Identities = 21/75 (28%), Positives = 34/75 (45%), Gaps = 3/75 (4%)

Query: 570 LEIPISGEPPPKAMWSRGDKAI---MEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINL 626
           L   +   PPP+  W + D  I   +  +G+ R  +     +L I     +DS  Y + +
Sbjct: 173 LTCTVQASPPPQVTWYKNDTRIDPRLFRAGKYRITNNYGLLSLEIRRCAIEDSATYTVRV 232

Query: 627 KNEAGEAHASIKVKV 641
           KN  G+A +  KV V
Sbjct: 233 KNAHGQASSFAKVLV 247



 Score = 33.9 bits (76), Expect = 0.91
 Identities = 36/132 (27%), Positives = 50/132 (37%), Gaps = 30/132 (22%)

Query: 302 ADPKLEVKWYKNGQEIRP----STKYIFEHKGCQRILFINNCQMTDDSEYYV-------- 349
           A P  +V WYKN   I P    + KY   +      L I  C + D + Y V        
Sbjct: 179 ASPPPQVTWYKNDTRIDPRLFRAGKYRITNNYGLLSLEIRRCAIEDSATYTVRVKNAHGQ 238

Query: 350 ------------TAGDEKCSTELFVRE---PPIMVTKQLEDTTAYCGERVELECEVSED- 393
                          D    +E+F R    P +  T  L+   A   E   L C  SED 
Sbjct: 239 ASSFAKVLVRTYLGKDAGFDSEIFKRSTFGPSVEFTSVLKPVFAREKEPFSLSCLFSEDV 298

Query: 394 -DA-NVKWFKNG 403
            DA +++WF++G
Sbjct: 299 LDAESIQWFRDG 310


>gi|157785645 SPEG complex locus [Homo sapiens]
          Length = 3267

 Score =  112 bits (280), Expect = 2e-24
 Identities = 159/647 (24%), Positives = 247/647 (38%), Gaps = 86/647 (13%)

Query: 303  DPKLEVKWYKNGQEIRPSTK-YIFEHKGCQRILFINNCQMTDDSEYYVTA----GDEKCS 357
            +PK  V W +N Q +RP  + +  E +G    L I   +  D   Y   A    G  +C 
Sbjct: 895  EPKPVVSWLRNRQPVRPDQRRFAEEAEGGLCRLRILAAERGDAGFYTCKAVNEYGARQCE 954

Query: 358  TELFVREPP----IMVTKQLEDTTAYCGERVELECEVS-EDDANVKWFKNGEEIIPGPKS 412
              L VR  P    + V   L+D     GE    EC V+   D  V W   G  + P    
Sbjct: 955  ARLEVRAHPESRSLAVLAPLQDVDVGAGEMALFECLVAGPTDVEVDWLCRGRLLQPA-LL 1013

Query: 413  RYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPL-----TDQ 467
            + ++  +G+K  L++    + D+  Y+   +  +     S  L     L PL      D 
Sbjct: 1014 KCKMHFDGRKCKLLLTSVHEDDSGVYTCKLSTAKDELTCSARLTVRPSLAPLFTRLLEDV 1073

Query: 468  TVNLGKEICLKCEISENIPG--KWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGD 525
             V  G+     C+IS   P    WT  G P++ES+ L++   G +H L IA+  +EDEG 
Sbjct: 1074 EVLEGRAARFDCKISGTPPPVVTWTHFGCPMEESENLRLRQDGGLHSLHIAHVGSEDEG- 1132

Query: 526  YVFAPDAYN----VTLPAKVHVIDP--------------PKI-------------ILDGL 554
             ++A  A N        A+++V +P              P I             I D L
Sbjct: 1133 -LYAVSAVNTHGQAHCSAQLYVEEPRTAASGPSSKLEKMPSIPEEPEQGELERLSIPDFL 1191

Query: 555  DADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIA 614
                 + V    +  LE  ++G P P   W      I     R R   Y D   LV    
Sbjct: 1192 RPLQDLEVGLAKEAMLECQVTGLPYPTISWFHNGHRIQSSDDR-RMTQYRDVHRLVFPAV 1250

Query: 615  ERDDSGVYHINLKNEAGEAHASIKVKVVD-FPDPP-VAPTVTEVGDDWCIMNWEPP---- 668
                +GVY   + N+ G+A     + V D  P PP  AP V  V      + W PP    
Sbjct: 1251 GPQHAGVYKSVIANKLGKAACYAHLYVTDVVPGPPDGAPQVVAVTGRMVTLTWNPPRSLD 1310

Query: 669  -AYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGI 727
             A D  S  L Y ++ +   S +W  L   L +E  +    + +GV +  R+ +      
Sbjct: 1311 MAIDPDS--LTYTVQHQVLGSDQWTALVTGL-REPGWAATGLRKGVQHIFRVLSTTVKSS 1367

Query: 728  SKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTE 787
            SKPS PS P   L     PTL    ++ D         PD +         +   F   E
Sbjct: 1368 SKPSPPSEPVQLL--EHGPTLEEAPAMLD--------KPDIVYVVEGQPASVTVTFNHVE 1417

Query: 788  DWIV--ANKDLIDKTKFTITGL--PTDAKIFVRVKAVNAAG------ASEPKYYSQPILV 837
              +V  + +  + + +  +  L  P D +  +R+  V+          +  ++ +Q   V
Sbjct: 1418 AQVVWRSCRGALLEARAGVYELSQPDDDQYCLRICRVSRRDMGALTCTARNRHGTQTCSV 1477

Query: 838  K-EIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKD 883
              E+ E P+      + +      GE     +  +GKP P++ W KD
Sbjct: 1478 TLELAEAPRF---ESIMEDVEVGAGETARFAVVVEGKPLPDIMWYKD 1521



 Score = 77.8 bits (190), Expect = 6e-14
 Identities = 138/644 (21%), Positives = 224/644 (34%), Gaps = 115/644 (17%)

Query: 302  ADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTA----GDEKCS 357
            A+P  +V W+K+G  +R   + +   +G +  L +   +  D   Y  TA    G   C+
Sbjct: 747  ANPPPQVSWHKDGSALRSEGRLLLRAEGERHTLLLREARAADAGSYMATATNELGQATCA 806

Query: 358  TELFVR--------------------------EP-------------------------- 365
              L VR                          EP                          
Sbjct: 807  ASLTVRPGGSTSPFSSPITSDEEYLSPPEEFPEPGETWPRTPTMKPSPSQNRRSSDTGSK 866

Query: 366  -PIMVTKQLEDTTAYCGERVELECEVS-EDDANVKWFKNGEEIIPGPKSRYRIRVEGKKH 423
             P      L D +   G+ V +   V  E    V W +N + + P  + R+    EG   
Sbjct: 867  APPTFKVSLMDQSVREGQDVIMSIRVQGEPKPVVSWLRNRQPVRPDQR-RFAEEAEGGLC 925

Query: 424  ILIIEGATKADAAEYSVMTTGG----QSSAKLSVDLKP----LKILTPLTDQTVNLGKEI 475
             L I  A + DA  Y+          Q  A+L V   P    L +L PL D  V  G+  
Sbjct: 926  RLRILAAERGDAGFYTCKAVNEYGARQCEARLEVRAHPESRSLAVLAPLQDVDVGAGEMA 985

Query: 476  CLKCEIS--ENIPGKWTKNGLPVQESD-RLKVVHKGRIHKLVIANALTEDEGDYVFAPDA 532
              +C ++   ++   W   G  +Q +  + K+   GR  KL++ +   +D G Y      
Sbjct: 986  LFECLVAGPTDVEVDWLCRGRLLQPALLKCKMHFDGRKCKLLLTSVHEDDSGVYTCKLST 1045

Query: 533  YNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIM 592
                L     +   P +          V V+ G   R +  ISG PPP   W+      M
Sbjct: 1046 AKDELTCSARLTVRPSLAPLFTRLLEDVEVLEGRAARFDCKISGTPPPVVTWTHFG-CPM 1104

Query: 593  EGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKV------------- 639
            E S  +R        +L I     +D G+Y ++  N  G+AH S ++             
Sbjct: 1105 EESENLRLRQDGGLHSLHIAHVGSEDEGLYAVSAVNTHGQAHCSAQLYVEEPRTAASGPS 1164

Query: 640  -KVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYD-----------------GGSPILGYFI 681
             K+   P  P  P   E+ +   I ++  P  D                    P + +F 
Sbjct: 1165 SKLEKMPSIPEEPEQGEL-ERLSIPDFLRPLQDLEVGLAKEAMLECQVTGLPYPTISWFH 1223

Query: 682  ERKKKQSSRWMRL-NFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPL 740
               + QSS   R+  +       F          Y+    +V A  + K +  +  +V  
Sbjct: 1224 NGHRIQSSDDRRMTQYRDVHRLVFPAVGPQHAGVYK----SVIANKLGKAACYAHLYVTD 1279

Query: 741  AVTSPPT-LLTVDSVTDTTVTMRWRPPDHIGAAGLD----GYVLEYCFEGTEDWIVANKD 795
             V  PP     V +VT   VT+ W PP  +  A +D     Y +++   G++ W      
Sbjct: 1280 VVPGPPDGAPQVVAVTGRMVTLTWNPPRSLDMA-IDPDSLTYTVQHQVLGSDQWTALVTG 1338

Query: 796  LIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKE 839
            L  +  +  TGL    +   RV +     +S+P   S+P+ + E
Sbjct: 1339 L-REPGWAATGLRKGVQHIFRVLSTTVKSSSKPSPPSEPVQLLE 1381



 Score = 62.8 bits (151), Expect = 2e-09
 Identities = 74/311 (23%), Positives = 123/311 (39%), Gaps = 55/311 (17%)

Query: 340 QMTDDSEYYVTAGDEKCSTELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDA-NVK 398
           + +DDS  YV+AG+E     +F  E P      L++     G  V L+C ++ +    V 
Sbjct: 705 ESSDDS--YVSAGEEPLEAPVF--EIP------LQNVVVAPGADVLLKCIITANPPPQVS 754

Query: 399 WFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTG--GQSSAKLSVDLK 456
           W K+G  +    + R  +R EG++H L++  A  ADA  Y    T   GQ++   S+ ++
Sbjct: 755 WHKDGSAL--RSEGRLLLRAEGERHTLLLREARAADAGSYMATATNELGQATCAASLTVR 812

Query: 457 PLKILTPLTDQTVNLGKEICLKCEISENIPGK-WTKNGLPVQESDRLKVVHKGRIHKLVI 515
           P    +P +    +  + +    E  E  PG+ W +   P  +    +            
Sbjct: 813 PGGSTSPFSSPITSDEEYLSPPEEFPE--PGETWPRT--PTMKPSPSQ------------ 856

Query: 516 ANALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPIS 575
            N  + D G    AP  + V+L  +                    +V  G  + + I + 
Sbjct: 857 -NRRSSDTGSK--APPTFKVSLMDQ--------------------SVREGQDVIMSIRVQ 893

Query: 576 GEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHA 635
           GEP P   W R  + +     R   E+      L I  AER D+G Y     NE G    
Sbjct: 894 GEPKPVVSWLRNRQPVRPDQRRFAEEAEGGLCRLRILAAERGDAGFYTCKAVNEYGARQC 953

Query: 636 SIKVKVVDFPD 646
             +++V   P+
Sbjct: 954 EARLEVRAHPE 964



 Score = 60.1 bits (144), Expect = 1e-08
 Identities = 30/92 (32%), Positives = 49/92 (53%), Gaps = 1/92 (1%)

Query: 1054 PMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAI-VDDPRYRMFSNQGVCTLE 1112
            P F   L++     G +  ++  V+G PKP ++W++N+  +  D  R+   +  G+C L 
Sbjct: 869  PTFKVSLMDQSVREGQDVIMSIRVQGEPKPVVSWLRNRQPVRPDQRRFAEEAEGGLCRLR 928

Query: 1113 IRKPSPYDGGTYCCKAVNDLGTVEIECKLEVK 1144
            I      D G Y CKAVN+ G  + E +LEV+
Sbjct: 929  ILAAERGDAGFYTCKAVNEYGARQCEARLEVR 960



 Score = 55.5 bits (132), Expect = 3e-07
 Identities = 29/93 (31%), Positives = 45/93 (48%)

Query: 1052 EAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTL 1111
            EAP+F  PL N     G +  L C +  NP P+++W K+  A+  + R  + +     TL
Sbjct: 720  EAPVFEIPLQNVVVAPGADVLLKCIITANPPPQVSWHKDGSALRSEGRLLLRAEGERHTL 779

Query: 1112 EIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVK 1144
             +R+    D G+Y   A N+LG       L V+
Sbjct: 780  LLREARAADAGSYMATATNELGQATCAASLTVR 812



 Score = 55.1 bits (131), Expect = 4e-07
 Identities = 30/97 (30%), Positives = 43/97 (44%), Gaps = 2/97 (2%)

Query: 1049 DFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGV 1108
            + +EAP F   + +    AG  A     V G P P I W K++V + +         +  
Sbjct: 1480 ELAEAPRFESIMEDVEVGAGETARFAVVVEGKPLPDIMWYKDEVLLTESSHVSFVYEENE 1539

Query: 1109 CTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVKV 1145
            C+L +      DGG Y C A N  G  E+ CK E+ V
Sbjct: 1540 CSLVVLSTGAQDGGVYTCTAQNLAG--EVSCKAELAV 1574



 Score = 48.5 bits (114), Expect = 4e-05
 Identities = 27/94 (28%), Positives = 42/94 (44%)

Query: 1051 SEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCT 1110
            S AP+FT+ L +   + G  A  +C + G P P +TW      + +    R+  + G+ +
Sbjct: 1061 SLAPLFTRLLEDVEVLEGRAARFDCKISGTPPPVVTWTHFGCPMEESENLRLRQDGGLHS 1120

Query: 1111 LEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVK 1144
            L I      D G Y   AVN  G      +L V+
Sbjct: 1121 LHIAHVGSEDEGLYAVSAVNTHGQAHCSAQLYVE 1154



 Score = 48.5 bits (114), Expect = 4e-05
 Identities = 82/357 (22%), Positives = 136/357 (38%), Gaps = 48/357 (13%)

Query: 811  AKIFVRVKAVNAAGASEPKYYSQPILVKEII--EPPKIRIPRHLKQTYIRRVGEAVNLVI 868
            A+++V      A+G S  K    P + +E    E  ++ IP  L+      VG A   ++
Sbjct: 1149 AQLYVEEPRTAASGPSS-KLEKMPSIPEEPEQGELERLSIPDFLRPLQDLEVGLAKEAML 1207

Query: 869  PFQ--GKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAER-SHSGKYDLQV--KVD 923
              Q  G P P ++W  +G  I  +         D    +  A    H+G Y   +  K+ 
Sbjct: 1208 ECQVTGLPYPTISWFHNGHRIQSSDDRRMTQYRDVHRLVFPAVGPQHAGVYKSVIANKLG 1267

Query: 924  KFVETASIDIQIIDRPGPPQ-IVKIEDVWGENVALTWTPPKDDGNA----AITGYTIQKA 978
            K    A + +  +  PGPP    ++  V G  V LTW PP+    A    ++T YT+Q  
Sbjct: 1268 KAACYAHLYVTDVV-PGPPDGAPQVVAVTGRMVTLTWNPPRSLDMAIDPDSLT-YTVQHQ 1325

Query: 979  DKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGK 1038
               S +W  ++          T L  G ++ FRV S  +   S+ +  ++   ++     
Sbjct: 1326 VLGSDQWTALVTGLREPGWAATGLRKGVQHIFRVLSTTVKSSSKPSPPSEPVQLLEH--- 1382

Query: 1039 IYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIV--- 1095
                P  E     EAP         Y + G  A++  +   + + ++ W   + A++   
Sbjct: 1383 ---GPTLE-----EAPAMLDKPDIVYVVEGQPASVTVTF-NHVEAQVVWRSCRGALLEAR 1433

Query: 1096 ---------DDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1143
                     DD +Y          L I + S  D G   C A N  GT      LE+
Sbjct: 1434 AGVYELSQPDDDQY---------CLRICRVSRRDMGALTCTARNRHGTQTCSVTLEL 1481



 Score = 46.6 bits (109), Expect = 1e-04
 Identities = 29/91 (31%), Positives = 42/91 (46%), Gaps = 1/91 (1%)

Query: 1054 PMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFS-NQGVCTLE 1112
            P+F   L +   + G  ATL C     P P I+WMK+K ++  +P   + S   G   L 
Sbjct: 2584 PVFHIKLKDQVLLEGEAATLLCLPAACPAPHISWMKDKKSLRSEPSVIIVSCKDGRQLLS 2643

Query: 1113 IRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1143
            I +      G Y C A N LG++   C + V
Sbjct: 2644 IPRAGKRHAGLYECSATNVLGSITSSCTVAV 2674



 Score = 43.5 bits (101), Expect = 0.001
 Identities = 28/91 (30%), Positives = 39/91 (42%), Gaps = 7/91 (7%)

Query: 1053 APMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLE 1112
            AP+F +PL N    AG +  L   V G P+P + W +      D       + +  C L 
Sbjct: 42   APVFLRPLKNAAVCAGSDVRLRVVVSGTPQPSLRWFR------DGQLLPAPAPEPSC-LW 94

Query: 1113 IRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1143
            +R+    D G Y C A N+ G    E  L V
Sbjct: 95   LRRCGAQDAGVYSCMAQNERGRASCEAVLTV 125



 Score = 43.1 bits (100), Expect = 0.002
 Identities = 36/161 (22%), Positives = 63/161 (39%), Gaps = 5/161 (3%)

Query: 861  GEAVNLVIPFQGKPRPELTWKKDGAEI--DKNQINIRNSETDTIIFIRKAERSHSGKYDL 918
            GEA  L+      P P ++W KD   +  + + I +   +   ++ I +A + H+G Y+ 
Sbjct: 2598 GEAATLLCLPAACPAPHISWMKDKKSLRSEPSVIIVSCKDGRQLLSIPRAGKRHAGLYEC 2657

Query: 919  QVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKA 978
                     T+S  + +   PG     ++   + +   + W P   D  A  T YT+++ 
Sbjct: 2658 SATNVLGSITSSCTVAVARVPGKLAPPEVPQTYQDTALVLWKP--GDSRAPCT-YTLERR 2714

Query: 979  DKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCG 1019
                  W  V          +T L +G    FRV   N  G
Sbjct: 2715 VDGESVWHPVSSGIPDCYYNVTHLPVGVTVRFRVACANRAG 2755



 Score = 42.4 bits (98), Expect = 0.003
 Identities = 26/89 (29%), Positives = 39/89 (43%), Gaps = 8/89 (8%)

Query: 562 VIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGV 621
           V AG+ +RL + +SG P P   W R         G++     P+ S L +      D+GV
Sbjct: 54  VCAGSDVRLRVVVSGTPQPSLRWFR--------DGQLLPAPAPEPSCLWLRRCGAQDAGV 105

Query: 622 YHINLKNEAGEAHASIKVKVVDFPDPPVA 650
           Y    +NE G A     + V++  D   A
Sbjct: 106 YSCMAQNERGRASCEAVLTVLEVGDSETA 134



 Score = 39.3 bits (90), Expect = 0.022
 Identities = 28/100 (28%), Positives = 43/100 (43%), Gaps = 4/100 (4%)

Query: 560  VTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDS 619
            V V AG   R  + + G+P P  MW + D+ ++  S  +      +  +LV+      D 
Sbjct: 1494 VEVGAGETARFAVVVEGKPLPDIMWYK-DEVLLTESSHVSFVYEENECSLVVLSTGAQDG 1552

Query: 620  GVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDD 659
            GVY    +N AGE     ++ V        A  V  VG+D
Sbjct: 1553 GVYTCTAQNLAGEVSCKAELAV---HSAQTAMEVEGVGED 1589



 Score = 39.3 bits (90), Expect = 0.022
 Identities = 44/193 (22%), Positives = 71/193 (36%), Gaps = 8/193 (4%)

Query: 578  PPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASI 637
            P P   W +  K++      I          L I  A +  +G+Y  +  N  G   +S 
Sbjct: 2611 PAPHISWMKDKKSLRSEPSVIIVSCKDGRQLLSIPRAGKRHAGLYECSATNVLGSITSSC 2670

Query: 638  KVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFD 697
             V V   P     P V +   D  ++ W+P   D  +P   Y +ER+    S W  ++  
Sbjct: 2671 TVAVARVPGKLAPPEVPQTYQDTALVLWKPG--DSRAPCT-YTLERRVDGESVWHPVSSG 2727

Query: 698  LCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDT 757
            +  +  +    +  GV    R+   N  G   P   S   V +  T   + +   +  + 
Sbjct: 2728 I-PDCYYNVTHLPVGVTVRFRVACANRAG-QGPFSNSSEKVFVRGTQDSSAVPSAAHQEA 2785

Query: 758  TVT---MRWRPPD 767
             VT    R RPPD
Sbjct: 2786 PVTSRPARARPPD 2798



 Score = 31.2 bits (69), Expect = 5.9
 Identities = 20/80 (25%), Positives = 37/80 (46%), Gaps = 4/80 (5%)

Query: 838 KEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEI-DKNQINIRN 896
           +E +E P   IP    Q  +   G  V L       P P+++W KDG+ +  + ++ +R 
Sbjct: 716 EEPLEAPVFEIPL---QNVVVAPGADVLLKCIITANPPPQVSWHKDGSALRSEGRLLLRA 772

Query: 897 SETDTIIFIRKAERSHSGKY 916
                 + +R+A  + +G Y
Sbjct: 773 EGERHTLLLREARAADAGSY 792


>gi|21359935 Down syndrome cell adhesion molecule like 1 [Homo
            sapiens]
          Length = 2113

 Score =  111 bits (277), Expect = 4e-24
 Identities = 211/903 (23%), Positives = 347/903 (38%), Gaps = 113/903 (12%)

Query: 304  PKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDE-----KCST 358
            P   +KWYK+   +  + + +    G  ++  +      D+ EY  +   +       S 
Sbjct: 592  PYYSIKWYKDALLLPDNHRQVVFENGTLKLTDVQKGM--DEGEYLCSVLIQPQLSISQSV 649

Query: 359  ELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVK--WFKNGEEIIPGPKSRYRI 416
             + V+ PP++  +  E   A  G+ + + C VS  D  ++  W K+G+ II G      +
Sbjct: 650  HVAVKVPPLI--QPFEFPPASIGQLLYIPCVVSSGDMPIRITWRKDGQVIISGSG----V 703

Query: 417  RVEGKKHI--LIIEGATKADAAEYSVMTTGGQSSA----KLSVDLKPLKILTPLTDQTVN 470
             +E K+ +  L I   +      Y+ + +   ++     +L V + P  ++ P  +Q   
Sbjct: 704  TIESKEFMSSLQISSVSLKHNGNYTCIASNAAATVSRERQLIVRVPPRFVVQP-NNQDGI 762

Query: 471  LGKEICLKCEISENIPGK--WT--------KNGLPVQESDRLKVVHKGRIHKLVIANALT 520
             GK   L C +    P K  W         +   PV  + R++++       L+I + L 
Sbjct: 763  YGKAGVLNCSVDGYPPPKVMWKHAKGSGNPQQYHPVPLTGRIQILPNS---SLLIRHVLE 819

Query: 521  EDEGDYVF-APDAYNVTLPAKVHV-IDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEP 578
            ED G Y+  A +     +   + + +  P +I       NT   I G+   L     GE 
Sbjct: 820  EDIGYYLCQASNGVGTDISKSMFLTVKIPAMITSH---PNTTIAIKGHAKELNCTARGER 876

Query: 579  PPKAMWSRGDKAIMEGSGR---IRTESYPDS--STLVIDIAERDDSGVYHINLKNEAGEA 633
            P    W +GD  I         I T+   D   STL +  A+R DS  +  +  N  GE 
Sbjct: 877  PIIIRWEKGDTVIDPDRVMRYAIATKDNGDEVVSTLKLKPADRGDSVFFSCHAINSYGED 936

Query: 634  HASIKVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMR 693
               I++ V + PDPP    + EV      + W    +DG S I G+ IE K K  S W  
Sbjct: 937  RGLIQLTVQEPPDPPEL-EIREVKARSMNLRW-TQRFDGNSIITGFDIEYKNKSDS-WDF 993

Query: 694  LNFDLCKETTFEPKKMIE---GVAYEVRIFAVNAIGISKPSMP-SRPFVPLAVTSPPTLL 749
                     T     +++      Y +R+++ N IG S+PS   +      A   PP  +
Sbjct: 994  KQSTRNISPTINQANIVDLHPASVYSIRMYSFNKIGRSEPSKELTISTEEAAPDGPPMDV 1053

Query: 750  TVDSVTDTTVTMRWR-PPDHIGAAGLDGYVLEYCFEGT----EDWIVANKDLIDKTKFTI 804
            T+  VT  ++ + W+ P   +    + GY + Y         +  IV  K   D   +T+
Sbjct: 1054 TLQPVTSQSIQVTWKAPKKELQNGVIRGYQIGYRENSPGSNGQYSIVEMKATGDSEVYTL 1113

Query: 805  TGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAV 864
              L   A+  V V+A N AG            ++++   P    P +++   I     + 
Sbjct: 1114 DNLKKFAQYGVVVQAFNRAGTGPSSSEINATTLEDVPSQP----PENVRALSI----TSD 1165

Query: 865  NLVIPFQGKPRPELTWKKDGAE-------IDKNQINIRN-SETDTIIFIRKAERSHSGKY 916
              VI +   PR  L     G         +D     ++N + T   + +R  E+  +  Y
Sbjct: 1166 VAVISWSEPPRSTLNGVLKGYRVIFWSLYVDGEWGEMQNITTTRERVELRGMEKFTN--Y 1223

Query: 917  DLQV----KVDKFVETASIDIQI-IDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAIT 971
             +QV    +    V ++ + IQ   D PGPP  +K       +V ++W PP    N  I 
Sbjct: 1224 SVQVLAYTQAGDGVRSSVLYIQTKEDVPGPPAGIKAVPSSASSVVVSWLPPTKP-NGVIR 1282

Query: 972  GYTIQKADKKS-----MEWFTVIEH-YHRTSATITELVIGNEYYFRVFSENMCGLSEDAT 1025
             YTI  +   S      E+ T  E  ++R    I  L  G +Y   V +    G      
Sbjct: 1283 KYTIFCSSPGSGQPAPSEYETSPEQLFYR----IAHLNRGQQYLLWVAAVTSAGRGN--- 1335

Query: 1026 MTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKI 1085
             + E   I   GK     +      S     T P +        +  L C+  G+P P +
Sbjct: 1336 -SSEKVTIEPAGKAPAKII------SFGGTVTTPWMK-------DVRLPCNSVGDPAPAV 1381

Query: 1086 TWMK---NKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLE 1142
             W K   +    V    +R+    G  TL +R     D G Y C A N  G   I   L 
Sbjct: 1382 KWTKDSEDSAIPVSMDGHRLIHTNG--TLLLRAVKAEDSGYYTCTATNTGGFDTIIVNLL 1439

Query: 1143 VKV 1145
            V+V
Sbjct: 1440 VQV 1442



 Score = 63.9 bits (154), Expect = 8e-10
 Identities = 138/735 (18%), Positives = 263/735 (35%), Gaps = 86/735 (11%)

Query: 341  MTDDSEYYVTAGDEKCSTEL-----FVREPPIMVTKQLEDTTAYCGERVELECEV-SEDD 394
            + +D  YY+        T++        + P M+T     T A  G   EL C    E  
Sbjct: 818  LEEDIGYYLCQASNGVGTDISKSMFLTVKIPAMITSHPNTTIAIKGHAKELNCTARGERP 877

Query: 395  ANVKWFKNGEEIIPGPKSRYRIRVEGKKHILI----IEGATKADAAEYS--VMTTGGQSS 448
              ++W K    I P    RY I  +     ++    ++ A + D+  +S   + + G+  
Sbjct: 878  IIIRWEKGDTVIDPDRVMRYAIATKDNGDEVVSTLKLKPADRGDSVFFSCHAINSYGEDR 937

Query: 449  AKLSVDLK-----PLKILTPLTDQTVNL-------GKEICLKCEIS-ENIPGKW-----T 490
              + + ++     P   +  +  +++NL       G  I    +I  +N    W     T
Sbjct: 938  GLIQLTVQEPPDPPELEIREVKARSMNLRWTQRFDGNSIITGFDIEYKNKSDSWDFKQST 997

Query: 491  KNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKII 550
            +N  P      +  +H   ++ +             +++ +    + P+K   I   +  
Sbjct: 998  RNISPTINQANIVDLHPASVYSI------------RMYSFNKIGRSEPSKELTISTEEAA 1045

Query: 551  LDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTL- 609
             DG   D T+  +    ++    ++ + P K +       ++ G      E+ P S+   
Sbjct: 1046 PDGPPMDVTLQPVTSQSIQ----VTWKAPKKEL----QNGVIRGYQIGYRENSPGSNGQY 1097

Query: 610  -VIDIAERDDSGVYHI-NLK------------NEAGEAHASIKVKVVDFPDPPVAPT--- 652
             ++++    DS VY + NLK            N AG   +S ++      D P  P    
Sbjct: 1098 SIVEMKATGDSEVYTLDNLKKFAQYGVVVQAFNRAGTGPSSSEINATTLEDVPSQPPENV 1157

Query: 653  -VTEVGDDWCIMNW-EPPAYDGGSPILGY-FIERKKKQSSRWMRLNFDLCKETTFEPKKM 709
                +  D  +++W EPP       + GY  I         W  +          E + M
Sbjct: 1158 RALSITSDVAVISWSEPPRSTLNGVLKGYRVIFWSLYVDGEWGEMQNITTTRERVELRGM 1217

Query: 710  IEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHI 769
             +   Y V++ A    G    S          V  PP  +     + ++V + W PP   
Sbjct: 1218 EKFTNYSVQVLAYTQAGDGVRSSVLYIQTKEDVPGPPAGIKAVPSSASSVVVSWLPPTKP 1277

Query: 770  GAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKF-TITGLPTDAKIFVRVKAVNAAGASEP 828
                +  Y +     G+     +  +   +  F  I  L    +  + V AV +AG    
Sbjct: 1278 NGV-IRKYTIFCSSPGSGQPAPSEYETSPEQLFYRIAHLNRGQQYLLWVAAVTSAGRGNS 1336

Query: 829  KYYSQPILVKEIIEPPK--IRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAE 886
               S+ + ++   + P   I     +   +++ V    N V    G P P + W KD  +
Sbjct: 1337 ---SEKVTIEPAGKAPAKIISFGGTVTTPWMKDVRLPCNSV----GDPAPAVKWTKDSED 1389

Query: 887  --IDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQI 944
              I  +    R   T+  + +R  +   SG Y          +T  +++ +   P  P++
Sbjct: 1390 SAIPVSMDGHRLIHTNGTLLLRAVKAEDSGYYTCTATNTGGFDTIIVNLLVQVPPDQPRL 1449

Query: 945  VKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVI 1004
              +      ++ LTW P  D+G ++I G+ +Q +   S EW  V       S  +  L  
Sbjct: 1450 T-VSKTSASSITLTWIPG-DNGGSSIRGFVLQYSVDNSEEWKDVFISSSERSFKLDSLKC 1507

Query: 1005 GNEYYFRVFSENMCG 1019
            G  Y  ++ ++N  G
Sbjct: 1508 GTWYKVKLAAKNSVG 1522



 Score = 57.0 bits (136), Expect = 1e-07
 Identities = 88/383 (22%), Positives = 148/383 (38%), Gaps = 42/383 (10%)

Query: 308 VKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTE-------- 359
           V W K+   I P  ++   + G    L+I++ Q  D    Y      K S E        
Sbjct: 219 VSWEKDTVSIIPEHRFFITYHGG---LYISDVQKEDALSTYRCITKHKYSGETRQSNGAR 275

Query: 360 LFVREPPIMVTKQLE---DTTAYCGERVELECEVSEDDAN-VKWFKNGEEIIPGPKSRYR 415
           L V +P   +   L+       + G  VEL C  S      ++W K+G  +     SR+ 
Sbjct: 276 LSVTDPAESIPTILDGFHSQEVWAGHTVELPCTASGYPIPAIRWLKDGRPL--PADSRWT 333

Query: 416 IRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLS---VDLKPLKI-LTPLTDQTVNL 471
            R+ G    L I      D+  Y    T    SA+ +   + + PL + LTP   +T  +
Sbjct: 334 KRITG----LTISDLRTEDSGTYICEVTNTFGSAEATGILMVIDPLHVTLTPKKLKT-GI 388

Query: 472 GKEICLKCEI--SENIPGKWTKNGLPVQESDRLKVVHKGRIHK-LVIANALTEDEGDY-V 527
           G  + L C +  S     +W +N   V   + + +  +G  ++ L+I +A     G Y  
Sbjct: 389 GSTVILSCALTGSPEFTIRWYRNTELVLPDEAISI--RGLSNETLLITSAQKSHSGAYQC 446

Query: 528 FAPDAYNVTLPAKVHVIDP--PKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWS 585
           FA           +  ++   P+I+     + +   V  G +  L     G PPP   W+
Sbjct: 447 FATRKAQTAQDFAIIALEDGTPRIV----SSFSEKVVNPGEQFSLMCAAKGAPPPTVTWA 502

Query: 586 RGDKAIM-EGSGRIRTESYPDSSTLV---IDIAERDDSGVYHINLKNEAGEAHASIKVKV 641
             D+ I+ +GS R    +  D +T+    +   +  D GVY    +N  G A    ++ V
Sbjct: 503 LDDEPIVRDGSHRTNQYTMSDGTTISHMNVTGPQIRDGGVYRCTARNLVGSAEYQARINV 562

Query: 642 VDFPDPPVAPTVTEVGDDWCIMN 664
              P       +T V     ++N
Sbjct: 563 RGPPSIRAMRNITAVAGRDTLIN 585



 Score = 55.5 bits (132), Expect = 3e-07
 Identities = 54/191 (28%), Positives = 83/191 (43%), Gaps = 17/191 (8%)

Query: 546  PPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRG--DKAI---MEGSGRIRT 600
            P KII  G     TVT      +RL     G+P P   W++   D AI   M+G   I T
Sbjct: 1349 PAKIISFG----GTVTTPWMKDVRLPCNSVGDPAPAVKWTKDSEDSAIPVSMDGHRLIHT 1404

Query: 601  ESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGDDW 660
                 + TL++   + +DSG Y     N  G     + + V   PD P   TV++     
Sbjct: 1405 -----NGTLLLRAVKAEDSGYYTCTATNTGGFDTIIVNLLVQVPPDQP-RLTVSKTSASS 1458

Query: 661  CIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIF 720
              + W  P  +GGS I G+ ++     S  W  + F    E +F+   +  G  Y+V++ 
Sbjct: 1459 ITLTW-IPGDNGGSSIRGFVLQYSVDNSEEWKDV-FISSSERSFKLDSLKCGTWYKVKLA 1516

Query: 721  AVNAIGISKPS 731
            A N++G  + S
Sbjct: 1517 AKNSVGSGRIS 1527



 Score = 53.5 bits (127), Expect = 1e-06
 Identities = 86/352 (24%), Positives = 138/352 (39%), Gaps = 72/352 (20%)

Query: 800  TKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRI-PRHLKQTYIR 858
            T  TI+ L T+       +  N  G++E    +  IL+  +I+P  + + P+ LK     
Sbjct: 337  TGLTISDLRTEDSGTYICEVTNTFGSAE----ATGILM--VIDPLHVTLTPKKLKTG--- 387

Query: 859  RVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQ-INIRNSETDTIIFIRKAERSHSGKYD 917
             +G  V L     G P   + W ++   +  ++ I+IR    +T++ I  A++SHSG Y 
Sbjct: 388  -IGSTVILSCALTGSPEFTIRWYRNTELVLPDEAISIRGLSNETLL-ITSAQKSHSGAY- 444

Query: 918  LQVKVDKFVETASIDIQIIDRPGPPQIVKI--EDVW--GENVAL------------TWT- 960
             Q    +  +TA     I    G P+IV    E V   GE  +L            TW  
Sbjct: 445  -QCFATRKAQTAQDFAIIALEDGTPRIVSSFSEKVVNPGEQFSLMCAAKGAPPPTVTWAL 503

Query: 961  ---PPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENM 1017
               P   DG+     YT+           T I H + T   I +   G  Y  R  + N+
Sbjct: 504  DDEPIVRDGSHRTNQYTMSDG--------TTISHMNVTGPQIRD---GGVY--RCTARNL 550

Query: 1018 CGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSV 1077
             G +E                      Y+       P   + + N  A+AG +  +NC V
Sbjct: 551  VGSAE----------------------YQARINVRGPPSIRAMRNITAVAGRDTLINCRV 588

Query: 1078 RGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAV 1129
             G P   I W K+ + + D+ R  +F N  +   +++K    D G Y C  +
Sbjct: 589  IGYPYYSIKWYKDALLLPDNHRQVVFENGTLKLTDVQK--GMDEGEYLCSVL 638



 Score = 52.8 bits (125), Expect = 2e-06
 Identities = 142/724 (19%), Positives = 267/724 (36%), Gaps = 93/724 (12%)

Query: 304  PKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTELF-- 361
            P+  ++WY+N + + P           + +L I + Q +    Y   A  +  + + F  
Sbjct: 402  PEFTIRWYRNTELVLPDEAISIRGLSNETLL-ITSAQKSHSGAYQCFATRKAQTAQDFAI 460

Query: 362  --VREPPIMVTKQLEDTTAYCGERVELECEV-SEDDANVKWFKNGEEIIPGPKSR---YR 415
              + +    +     +     GE+  L C         V W  + E I+     R   Y 
Sbjct: 461  IALEDGTPRIVSSFSEKVVNPGEQFSLMCAAKGAPPPTVTWALDDEPIVRDGSHRTNQYT 520

Query: 416  IRVEGKKHILIIEGATKADAAEY--SVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNLGK 473
            +        + + G    D   Y  +     G +  +  ++++    +  + + T   G+
Sbjct: 521  MSDGTTISHMNVTGPQIRDGGVYRCTARNLVGSAEYQARINVRGPPSIRAMRNITAVAGR 580

Query: 474  EICLKCEI--SENIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDY---VF 528
            +  + C +        KW K+ L + ++ R  V   G +    +   +  DEG+Y   V 
Sbjct: 581  DTLINCRVIGYPYYSIKWYKDALLLPDNHRQVVFENGTLKLTDVQKGM--DEGEYLCSVL 638

Query: 529  APDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPI-SGEPPPKAMWSRG 587
                 +++    V V  PP I               G  L +   + SG+ P +  W + 
Sbjct: 639  IQPQLSISQSVHVAVKVPPLI-----QPFEFPPASIGQLLYIPCVVSSGDMPIRITWRKD 693

Query: 588  DKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDP 647
             + I+ GSG +  ES    S+L I       +G Y     N A       ++ V   P  
Sbjct: 694  GQVIISGSG-VTIESKEFMSSLQISSVSLKHNGNYTCIASNAAATVSRERQLIVRVPPRF 752

Query: 648  PVAPT-----VTEVGDDWCIMNWEPP-------AYDGGSPILGYFIERKKK-----QSSR 690
             V P        + G   C ++  PP       A   G+P   + +    +      SS 
Sbjct: 753  VVQPNNQDGIYGKAGVLNCSVDGYPPPKVMWKHAKGSGNPQQYHPVPLTGRIQILPNSSL 812

Query: 691  WMR------LNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTS 744
             +R      + + LC+ +      + + +   V+I A+         + S P   +A+  
Sbjct: 813  LIRHVLEEDIGYYLCQASNGVGTDISKSMFLTVKIPAM---------ITSHPNTTIAIKG 863

Query: 745  PPTLLTVDSVTDTTVTMRWRPPDHIGAAGLD-GYVLEYCFEGTEDWIVANKDLIDKTKFT 803
                L   +  +  + +RW   D +    +D   V+ Y         +A KD  D+   T
Sbjct: 864  HAKELNCTARGERPIIIRWEKGDTV----IDPDRVMRYA--------IATKDNGDEVVST 911

Query: 804  ITGLPTDA--KIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRI----PRHLKQTYI 857
            +   P D    +F    A+N+ G  E +   Q + V+E  +PP++ I     R +   + 
Sbjct: 912  LKLKPADRGDSVFFSCHAINSYG--EDRGLIQ-LTVQEPPDPPELEIREVKARSMNLRWT 968

Query: 858  RRV-GEAVNLVIPFQGKPRPELTW--KKDGAEIDK--NQINIRNSETDTIIFIRKAERSH 912
            +R  G ++      + K + + +W  K+    I    NQ NI +    ++  IR    + 
Sbjct: 969  QRFDGNSIITGFDIEYKNKSD-SWDFKQSTRNISPTINQANIVDLHPASVYSIRMYSFNK 1027

Query: 913  SGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDD-GNAAIT 971
             G+ +   ++    E A+ D       GPP  V ++ V  +++ +TW  PK +  N  I 
Sbjct: 1028 IGRSEPSKELTISTEEAAPD-------GPPMDVTLQPVTSQSIQVTWKAPKKELQNGVIR 1080

Query: 972  GYTI 975
            GY I
Sbjct: 1081 GYQI 1084



 Score = 52.4 bits (124), Expect = 2e-06
 Identities = 73/323 (22%), Positives = 125/323 (38%), Gaps = 56/323 (17%)

Query: 841  IEPPKIRIPRHLKQTYIRRV--GEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSE 898
            +  P   IP  L   + + V  G  V L     G P P + W KDG  +  +    R ++
Sbjct: 278  VTDPAESIPTILDGFHSQEVWAGHTVELPCTASGYPIPAIRWLKDGRPLPADS---RWTK 334

Query: 899  TDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALT 958
              T + I       SG Y  +V  + F    +  I ++  P               + +T
Sbjct: 335  RITGLTISDLRTEDSGTYICEV-TNTFGSAEATGILMVIDP---------------LHVT 378

Query: 959  WTPPK---DDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSE 1015
             TP K     G+  I    +  + + ++ W+             TELV+ +E      + 
Sbjct: 379  LTPKKLKTGIGSTVILSCALTGSPEFTIRWY-----------RNTELVLPDE------AI 421

Query: 1016 NMCGLSEDATMTKESAVIARDGKIY-----KNPVYEDFDFSEAPMFTQPLVNTYA----I 1066
            ++ GLS + T+   SA  +  G        K    +DF        T  +V++++     
Sbjct: 422  SIRGLSNE-TLLITSAQKSHSGAYQCFATRKAQTAQDFAIIALEDGTPRIVSSFSEKVVN 480

Query: 1067 AGYNATLNCSVRGNPKPKITWMKNKVAIVDD-----PRYRMFSNQGVCTLEIRKPSPYDG 1121
             G   +L C+ +G P P +TW  +   IV D      +Y M     +  + +  P   DG
Sbjct: 481  PGEQFSLMCAAKGAPPPTVTWALDDEPIVRDGSHRTNQYTMSDGTTISHMNVTGPQIRDG 540

Query: 1122 GTYCCKAVNDLGTVEIECKLEVK 1144
            G Y C A N +G+ E + ++ V+
Sbjct: 541  GVYRCTARNLVGSAEYQARINVR 563



 Score = 48.1 bits (113), Expect = 5e-05
 Identities = 137/636 (21%), Positives = 228/636 (35%), Gaps = 114/636 (17%)

Query: 539  AKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRI 598
            A++ V DP + I   LD  ++  V AG+ + L    SG P P   W +  + +   S   
Sbjct: 274  ARLSVTDPAESIPTILDGFHSQEVWAGHTVELPCTASGYPIPAIRWLKDGRPLPADSRWT 333

Query: 599  RTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEVGD 658
            +       + L I     +DSG Y   + N  G A A+  + V+D     + P   + G 
Sbjct: 334  KR-----ITGLTISDLRTEDSGTYICEVTNTFGSAEATGILMVIDPLHVTLTPKKLKTGI 388

Query: 659  DWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVR 718
                         G + IL   +    + + RW R N +L      +    I G++ E  
Sbjct: 389  -------------GSTVILSCALTGSPEFTIRWYR-NTELVLP---DEAISIRGLSNETL 431

Query: 719  IFAVNAIGIS--------KPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVT---------- 760
            +        S        + +  ++ F  +A+    T   V S ++  V           
Sbjct: 432  LITSAQKSHSGAYQCFATRKAQTAQDFAIIALEDG-TPRIVSSFSEKVVNPGEQFSLMCA 490

Query: 761  MRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAV 820
             +  PP  +  A  D  ++      T  + +++   I  +   +TG         R  A 
Sbjct: 491  AKGAPPPTVTWALDDEPIVRDGSHRTNQYTMSDGTTI--SHMNVTGPQIRDGGVYRCTAR 548

Query: 821  NAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTW 880
            N  G++E   Y   I V+    PP IR  R++        G    +     G P   + W
Sbjct: 549  NLVGSAE---YQARINVRG---PPSIRAMRNITAV----AGRDTLINCRVIGYPYYSIKW 598

Query: 881  KKDGAEIDKN--QINIRNSE---TDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQI 935
             KD   +  N  Q+   N     TD    + + E   S     Q+ + + V  A + +  
Sbjct: 599  YKDALLLPDNHRQVVFENGTLKLTDVQKGMDEGEYLCSVLIQPQLSISQSVHVA-VKVPP 657

Query: 936  IDRPG--PP----QIVKIEDVWGEN---VALTWTPPKDDGNAAITGYTIQKADKKSMEWF 986
            + +P   PP    Q++ I  V       + +TW   + DG   I+G  +    K+ M   
Sbjct: 658  LIQPFEFPPASIGQLLYIPCVVSSGDMPIRITW---RKDGQVIISGSGVTIESKEFM--- 711

Query: 987  TVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYE 1046
                    +S  I+ + + +   +   + N       AT+++E  +I R           
Sbjct: 712  --------SSLQISSVSLKHNGNYTCIASNAA-----ATVSRERQLIVR----------- 747

Query: 1047 DFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVA--------IVDDP 1098
                   P F     N   I G    LNCSV G P PK+ W   K +        +    
Sbjct: 748  -----VPPRFVVQPNNQDGIYGKAGVLNCSVDGYPPPKVMWKHAKGSGNPQQYHPVPLTG 802

Query: 1099 RYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGT 1134
            R ++  N    +L IR     D G Y C+A N +GT
Sbjct: 803  RIQILPNS---SLLIRHVLEEDIGYYLCQASNGVGT 835



 Score = 40.8 bits (94), Expect = 0.007
 Identities = 37/134 (27%), Positives = 61/134 (45%), Gaps = 14/134 (10%)

Query: 738  VPLAVTSPPTL--LTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKD 795
            V L V  PP    LTV   + +++T+ W P D+ G + + G+VL+Y  + +E+W    KD
Sbjct: 1436 VNLLVQVPPDQPRLTVSKTSASSITLTWIPGDN-GGSSIRGFVLQYSVDNSEEW----KD 1490

Query: 796  LI---DKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHL 852
            +     +  F +  L       V++ A N+ G+      S+ I  K     P     +HL
Sbjct: 1491 VFISSSERSFKLDSLKCGTWYKVKLAAKNSVGSGR---ISEIIEAKTHGREPSFSKDQHL 1547

Query: 853  KQTYIRRVGEAVNL 866
              T+I      +NL
Sbjct: 1548 -FTHINSTHARLNL 1560



 Score = 32.7 bits (73), Expect = 2.0
 Identities = 52/245 (21%), Positives = 90/245 (36%), Gaps = 29/245 (11%)

Query: 298 VVELADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCS 357
           VV   D  + + W K+GQ I   +    E K     L I++  +  +  Y   A +   +
Sbjct: 678 VVSSGDMPIRITWRKDGQVIISGSGVTIESKEFMSSLQISSVSLKHNGNYTCIASNAAAT 737

Query: 358 T----ELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDANVKWFKNGEEIIPGPKSR 413
                +L VR PP  V +       Y G+   L C V         +K+ +     P+  
Sbjct: 738 VSRERQLIVRVPPRFVVQPNNQDGIY-GKAGVLNCSVDGYPPPKVMWKHAKG-SGNPQQY 795

Query: 414 YRIRVEGKKHI-----LIIEGATKADAAEYSVMTTGG---QSSAKLSVDLKPLKILTPLT 465
           + + + G+  I     L+I    + D   Y    + G     S  + + +K   ++T   
Sbjct: 796 HPVPLTGRIQILPNSSLLIRHVLEEDIGYYLCQASNGVGTDISKSMFLTVKIPAMITSHP 855

Query: 466 DQTVNL---GKEICLKCEISENIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTED 522
           + T+ +    KE+         I  +W K            V+   R+ +  IA   T+D
Sbjct: 856 NTTIAIKGHAKELNCTARGERPIIIRWEKGD---------TVIDPDRVMRYAIA---TKD 903

Query: 523 EGDYV 527
            GD V
Sbjct: 904 NGDEV 908


>gi|19743806 roundabout 1 isoform b [Homo sapiens]
          Length = 1612

 Score =  105 bits (261), Expect = 3e-22
 Identities = 126/476 (26%), Positives = 180/476 (37%), Gaps = 65/476 (13%)

Query: 304 PKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGD------EKCS 357
           P+  + W K+G  +    + I    G   I +        D+  YV  G       E   
Sbjct: 159 PEPTISWKKDGSPLDDKDERITIRGGKLMITYTRK----SDAGKYVCVGTNMVGERESEV 214

Query: 358 TELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDA-NVKWFKNGEEIIPGPKSRYRI 416
            EL V E P  V K+  +      +  E +CE   D    V+W K+  E+   PKSRY I
Sbjct: 215 AELTVLERPSFV-KRPSNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGEL---PKSRYEI 270

Query: 417 RVEGKKHILIIEGATKADAAEYSV----MTTGGQSSAKLSVDLKPLKILTPLTDQTVNLG 472
           R +   H L I   T  D   Y+     M    ++SA L+V   P  ++ P  DQ V LG
Sbjct: 271 RDD---HTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQEPPHFVVKP-RDQVVALG 326

Query: 473 KEICLKCEISENIPGK--WTKNGL--------PVQESDRLKVVHKGRIHKLVIANALTED 522
           + +  +CE + N      W + G         P Q S R  V   G    L I N    D
Sbjct: 327 RTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTG---DLTITNVQRSD 383

Query: 523 EGDYVFAP--DAYNVTLPAKVHVID-----PPKIILDGLDADNTVTVIAGNKLRLEIPIS 575
            G Y+      A ++   A + V D     PP +I  G       TV       L    +
Sbjct: 384 VGYYICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQG---PVNQTVAVDGTFVLSCVAT 440

Query: 576 GEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHA 635
           G P P  +W +    +     RI+     ++  L I  A+  D+G Y       +GEA  
Sbjct: 441 GSPVPTILWRKDGVLVSTQDSRIKQL---ENGVLQIRYAKLGDTGRYTCIASTPSGEATW 497

Query: 636 SIKVKVVDF---------------PDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYF 680
           S  ++V +F               P  P  P VT+V  +   ++W+P    G +P   Y 
Sbjct: 498 SAYIEVQEFGVPVQPPRPTDPNLIPSAPSKPEVTDVSRNTVTLSWQPNLNSGATP-TSYI 556

Query: 681 IERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRP 736
           IE     S    +   +  K  T   K +     Y   + A NA GIS PS  S P
Sbjct: 557 IEAFSHASGSSWQTVAENVKTETSAIKGLKPNAIYLFLVRAANAYGISDPSQISDP 612



 Score = 80.5 bits (197), Expect = 9e-15
 Identities = 177/766 (23%), Positives = 282/766 (36%), Gaps = 107/766 (13%)

Query: 375  DTTAYCGERVELECEV--SEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATK 432
            D     GE   +EC+      +  + W K+G    P      RI + G K  L+I    K
Sbjct: 139  DVMVAVGEPAVMECQPPRGHPEPTISWKKDGS---PLDDKDERITIRGGK--LMITYTRK 193

Query: 433  ADAAEYSVMTT---GGQSS--AKLSVDLKPLKILTPLTDQTVNLGKEICLKCEI-SENIP 486
            +DA +Y  + T   G + S  A+L+V  +P  +  P ++  V +      KCE   + +P
Sbjct: 194  SDAGKYVCVGTNMVGERESEVAELTVLERPSFVKRP-SNLAVTVDDSAEFKCEARGDPVP 252

Query: 487  G-KWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAY--NVTLPAKVHV 543
              +W K+   + +S R ++      H L I      D G Y    +         A + V
Sbjct: 253  TVRWRKDDGELPKS-RYEIRDD---HTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTV 308

Query: 544  IDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESY 603
             +PP  ++   D      V  G  +  +   +G P P   W R      EGS  +     
Sbjct: 309  QEPPHFVVKPRDQ----VVALGRTVTFQCEATGNPQPAIFWRR------EGSQNLLFSYQ 358

Query: 604  PDSST----------LVIDIAERDDSGVYHINLKNEAG----EAHASIKVKVVDFPDP-- 647
            P  S+          L I   +R D G Y     N AG    +A+  +   + D P P  
Sbjct: 359  PPQSSSRFSVSQTGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIADRPPPVI 418

Query: 648  ---PVAPTVTEVGDDW--CIMNWEPPA---YDGGSPILGYFIERKKKQSSRWMRLNFDLC 699
               PV  TV   G     C+    P     +     ++     R K+  +  +++ +   
Sbjct: 419  RQGPVNQTVAVDGTFVLSCVATGSPVPTILWRKDGVLVSTQDSRIKQLENGVLQIRYAKL 478

Query: 700  KET------TFEPKKMIEGVAY-EVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVD 752
             +T         P       AY EV+ F V       P  P RP  P  + S P+   V 
Sbjct: 479  GDTGRYTCIASTPSGEATWSAYIEVQEFGV-------PVQPPRPTDPNLIPSAPSKPEVT 531

Query: 753  SVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAK 812
             V+  TVT+ W+P  + GA      +  +       W    +++  +T   I GL  +A 
Sbjct: 532  DVSRNTVTLSWQPNLNSGATPTSYIIEAFSHASGSSWQTVAENVKTETS-AIKGLKPNAI 590

Query: 813  IFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAV-NLVIP-F 870
                V+A NA G S+P   S P+  ++++ P    +     Q   R +G AV +L  P  
Sbjct: 591  YLFLVRAANAYGISDPSQISDPVKTQDVL-PTSQGVDHKQVQ---RELGNAVLHLHNPTV 646

Query: 871  QGKPRPELTWKKD-------GAEIDKNQINIRNSETDTIIF-IRKAERSHSGKYDLQVKV 922
                  E+ W  D       G +I        + E+D ++F +R   ++     DL+  V
Sbjct: 647  LSSSSIEVHWTVDQQSQYIQGYKILYRPSGANHGESDWLVFEVRTPAKNSVVIPDLRKGV 706

Query: 923  DK-------FVETASIDIQI------IDRP-GPPQIVKI--EDVWGENVALTWTPPKDD- 965
            +        F E    D +I       + P  PPQ V +   D  G  + ++W PP +D 
Sbjct: 707  NYEIKARPFFNEFQGADSEIKFAKTLEEAPSAPPQGVTVSKNDGNGTAILVSWQPPPEDT 766

Query: 966  GNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDAT 1025
             N  +  Y +     ++             S  I  LV G  Y   V +    G    + 
Sbjct: 767  QNGMVQEYKVWCLGNETRYHINKTVDGSTFSVVIPFLVPGIRYSVEVAASTGAG----SG 822

Query: 1026 MTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNA 1071
            +  E   I  D   + NPV  +   S A   +  +     IAG  A
Sbjct: 823  VKSEPQFIQLDA--HGNPVSPEDQVSLAQQISDVVKQPAFIAGIGA 866



 Score = 68.9 bits (167), Expect = 3e-11
 Identities = 139/625 (22%), Positives = 234/625 (37%), Gaps = 76/625 (12%)

Query: 447  SSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCEISENIPG---KWTKNGLPVQ------ 497
            S ++L  +  P +I+   +D  V+ G+   L C+ +E  P    +W K G  V+      
Sbjct: 18   SGSRLRQEDFPPRIVEHPSDLIVSKGEPATLNCK-AEGRPTPTIEWYKGGERVETDKDDP 76

Query: 498  ESDRLKVVHKGRIHKLVIANALTE--DEGDYVFAPDAYNVTLPAKVHVIDPPKIIL--DG 553
             S R+ ++  G +  L I +      DEG YV    A N    A  H       IL  D 
Sbjct: 77   RSHRM-LLPSGSLFFLRIVHGRKSRPDEGVYVCV--ARNYLGEAVSHNASLEVAILRDDF 133

Query: 554  LDADNTVTVIAGNKLRLEI-PISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVID 612
                + V V  G    +E  P  G P P   W +    + +   RI          L+I 
Sbjct: 134  RQNPSDVMVAVGEPAVMECQPPRGHPEPTISWKKDGSPLDDKDERITIRG----GKLMIT 189

Query: 613  IAERDDSGVYHINLKNEAGEAHASI-KVKVVDFPD-----PPVAPTVTEVGDDWCIMNWE 666
               + D+G Y     N  GE  + + ++ V++ P        +A TV +  +  C    +
Sbjct: 190  YTRKSDAGKYVCVGTNMVGERESEVAELTVLERPSFVKRPSNLAVTVDDSAEFKCEARGD 249

Query: 667  PPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIG 726
            P               R +K      +  +++  + T + +K+  G        A N +G
Sbjct: 250  PVP-----------TVRWRKDDGELPKSRYEIRDDHTLKIRKVTAGDMGSYTCVAENMVG 298

Query: 727  ISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGT 786
             ++ S        L V  PP  +      D  V +         A G     + +  EG+
Sbjct: 299  KAEAS------ATLTVQEPPHFVV--KPRDQVVALGRTVTFQCEATGNPQPAIFWRREGS 350

Query: 787  EDWIVANKDLIDKTKF--------TITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVK 838
            ++ + + +     ++F        TIT +      +   + +N AG+   K Y +   V 
Sbjct: 351  QNLLFSYQPPQSSSRFSVSQTGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVI 410

Query: 839  EIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSE 898
                PP IR    + QT    V     L     G P P + W+KDG  +      I+  E
Sbjct: 411  ADRPPPVIR-QGPVNQTVA--VDGTFVLSCVATGSPVPTILWRKDGVLVSTQDSRIKQLE 467

Query: 899  TDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIID--------RPGPPQIV----- 945
             + ++ IR A+   +G+Y           T S  I++ +        RP  P ++     
Sbjct: 468  -NGVLQIRYAKLGDTGRYTCIASTPSGEATWSAYIEVQEFGVPVQPPRPTDPNLIPSAPS 526

Query: 946  --KIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKS-MEWFTVIEHYHRTSATITEL 1002
              ++ DV    V L+W P  + G A  T Y I+     S   W TV E+    ++ I  L
Sbjct: 527  KPEVTDVSRNTVTLSWQPNLNSG-ATPTSYIIEAFSHASGSSWQTVAENVKTETSAIKGL 585

Query: 1003 VIGNEYYFRVFSENMCGLSEDATMT 1027
                 Y F V + N  G+S+ + ++
Sbjct: 586  KPNAIYLFLVRAANAYGISDPSQIS 610



 Score = 54.3 bits (129), Expect = 7e-07
 Identities = 78/308 (25%), Positives = 122/308 (39%), Gaps = 69/308 (22%)

Query: 860  VGE-AVNLVIPFQGKPRPELTWKKDGAEID--KNQINIRNSETDTIIFIRKAERSHSGKY 916
            VGE AV    P +G P P ++WKKDG+ +D    +I IR  +    + I    +S +GKY
Sbjct: 144  VGEPAVMECQPPRGHPEPTISWKKDGSPLDDKDERITIRGGK----LMITYTRKSDAGKY 199

Query: 917  DLQVKVDKFVETAS--IDIQIIDRPG----PPQI-VKIED-------VWGENV-ALTWTP 961
             + V  +   E  S   ++ +++RP     P  + V ++D         G+ V  + W  
Sbjct: 200  -VCVGTNMVGERESEVAELTVLERPSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWR- 257

Query: 962  PKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLS 1021
             KDDG    + Y I+             +H    +  I ++  G+   +   +ENM G +
Sbjct: 258  -KDDGELPKSRYEIRD------------DH----TLKIRKVTAGDMGSYTCVAENMVGKA 300

Query: 1022 E-DATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGN 1080
            E  AT+T +                      E P F     +     G   T  C   GN
Sbjct: 301  EASATLTVQ----------------------EPPHFVVKPRDQVVALGRTVTFQCEATGN 338

Query: 1081 PKPKITWMK----NKVAIVDDPR-YRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTV 1135
            P+P I W +    N +     P+    FS      L I      D G Y C+ +N  G++
Sbjct: 339  PQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQRSDVGYYICQTLNVAGSI 398

Query: 1136 EIECKLEV 1143
              +  LEV
Sbjct: 399  ITKAYLEV 406



 Score = 49.7 bits (117), Expect = 2e-05
 Identities = 71/321 (22%), Positives = 122/321 (38%), Gaps = 58/321 (18%)

Query: 843  PPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSE---- 898
            PP  RI  H     + + GE   L    +G+P P + W K G  ++ ++ + R+      
Sbjct: 28   PP--RIVEHPSDLIVSK-GEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLP 84

Query: 899  TDTIIFIR----KAERSHSGKYDLQVKV---DKFVETASIDIQIID---RPGPPQIVKIE 948
            + ++ F+R    +  R   G Y    +    +     AS+++ I+    R  P  ++   
Sbjct: 85   SGSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILRDDFRQNPSDVMVAV 144

Query: 949  DVWGENVALTWTPPKDDGNAAIT----GYTIQKADKK-SMEWFTVIEHYHRTSATITELV 1003
               GE   +   PP+      I+    G  +   D++ ++    ++  Y R S     + 
Sbjct: 145  ---GEPAVMECQPPRGHPEPTISWKKDGSPLDDKDERITIRGGKLMITYTRKSDAGKYVC 201

Query: 1004 IGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNT 1063
            +G          NM G        +ES V              +    E P F +   N 
Sbjct: 202  VGT---------NMVG-------ERESEVA-------------ELTVLERPSFVKRPSNL 232

Query: 1064 YAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGT 1123
                  +A   C  RG+P P + W K+   +    RY +  +    TL+IRK +  D G+
Sbjct: 233  AVTVDDSAEFKCEARGDPVPTVRWRKDDGELPKS-RYEIRDDH---TLKIRKVTAGDMGS 288

Query: 1124 YCCKAVNDLGTVEIECKLEVK 1144
            Y C A N +G  E    L V+
Sbjct: 289  YTCVAENMVGKAEASATLTVQ 309



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 93/383 (24%), Positives = 143/383 (37%), Gaps = 60/383 (15%)

Query: 784  EGTEDWIVANKDLIDKT-KFTITG--------LPTDAKIFVRVKAVNAAGASEPKYYSQP 834
            E T  W      L DK  + TI G          +DA  +V V   N  G  E +     
Sbjct: 160  EPTISWKKDGSPLDDKDERITIRGGKLMITYTRKSDAGKYVCV-GTNMVGERESEVAELT 218

Query: 835  ILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINI 894
            +L +    P  ++ P +L  T    V ++       +G P P + W+KD  E+ K++  I
Sbjct: 219  VLER----PSFVKRPSNLAVT----VDDSAEFKCEARGDPVPTVRWRKDDGELPKSRYEI 270

Query: 895  RNSETDTIIFIRKAERSHSGKYDLQVK--VDKFVETASIDIQIIDRPGPPQ-IVKIEDVW 951
            R+  T   + IRK      G Y    +  V K   +A++ +Q      PP  +VK  D  
Sbjct: 271  RDDHT---LKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQ-----EPPHFVVKPRD-- 320

Query: 952  GENVALTWTPP---KDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSA------TITEL 1002
             + VAL  T     +  GN     +  ++  +  +  +   +   R S       TIT +
Sbjct: 321  -QVVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGDLTITNV 379

Query: 1003 VIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVN 1062
               +  Y+   + N+ G        + + VIA                   P+  Q  VN
Sbjct: 380  QRSDVGYYICQTLNVAGSIITKAYLEVTDVIAD---------------RPPPVIRQGPVN 424

Query: 1063 TYAIAGYNATLNCSVRGNPKPKITWMKNKVAI-VDDPRYRMFSNQGVCTLEIRKPSPYDG 1121
                      L+C   G+P P I W K+ V +   D R +   N GV  L+IR     D 
Sbjct: 425  QTVAVDGTFVLSCVATGSPVPTILWRKDGVLVSTQDSRIKQLEN-GV--LQIRYAKLGDT 481

Query: 1122 GTYCCKAVNDLGTVEIECKLEVK 1144
            G Y C A    G       +EV+
Sbjct: 482  GRYTCIASTPSGEATWSAYIEVQ 504



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 34/88 (38%), Positives = 40/88 (45%), Gaps = 10/88 (11%)

Query: 1068 GYNATLNCSVRGNPKPKITWMKNKVAI---VDDPR-YRMFSNQG----VCTLEIRKPSPY 1119
            G  ATLNC   G P P I W K    +    DDPR +RM    G    +  +  RK  P 
Sbjct: 43   GEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRKSRP- 101

Query: 1120 DGGTYCCKAVNDLG-TVEIECKLEVKVI 1146
            D G Y C A N LG  V     LEV ++
Sbjct: 102  DEGVYVCVARNYLGEAVSHNASLEVAIL 129


>gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens]
          Length = 3874

 Score =  105 bits (261), Expect = 3e-22
 Identities = 204/903 (22%), Positives = 331/903 (36%), Gaps = 139/903 (15%)

Query: 304  PKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEY----YVTAGDEKCSTE 359
            P  +V+W K+ Q + P   ++   +  Q +L I    + D+  Y    +  AG +    +
Sbjct: 245  PTPQVEWTKDRQPVLPGGPHLQVQEDGQ-VLRITGSHVGDEGRYQCVAFSPAGQQARDFQ 303

Query: 360  LFVREPP-IMVTKQLEDTTAYCGERVELECEV-SEDDANVKWFKNGEEIIPGPKSRYRIR 417
            L V  PP I  + +  +        V+L CE       N+ WFK+G  +   P S   + 
Sbjct: 304  LRVHAPPTIWGSNETGEVAVMEDHLVQLLCEARGVPTPNITWFKDGALL---PTSTKVVY 360

Query: 418  VEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVN------- 470
              G +  L +  A  +DA  Y+   +    +A+ +  L    +  P T +          
Sbjct: 361  TRGGRQ-LQLGRAQSSDAGVYTCKASNAVGAAEKATRLD---VYVPPTIEGAGGRPYVVK 416

Query: 471  --LGKEICLKCEISENIPG---KWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGD 525
               G+ + L+C ++   P     W   GLPV ES+  ++   G + +L      +     
Sbjct: 417  AVAGRPVALEC-VARGHPSPTLSWHHEGLPVAESNESRLETDGSVLRLESPGEASSGLYS 475

Query: 526  YVFAPDAYNVTLPAKVHVIDPPKIIL-DGLDADNTVTVIAGNKLRLEIPISGEPPPKAMW 584
             V +  A    L   V V  PP++++ +GL     VT I G  L L    SG P P   W
Sbjct: 476  CVASSPAGEAVLQYSVEVQVPPQLLVAEGL---GQVTTIVGQPLELPCQASGSPVPTIQW 532

Query: 585  SRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDF 644
             +  +   E +G    +     +TL ID  E D SG++     NEAG A A ++V V   
Sbjct: 533  LQNGRPAEELAG---VQVASQGTTLHIDHVELDHSGLFACQATNEAGTAGAEVEVSV--- 586

Query: 645  PDPPVAPTVTEVGDDWCIMNW------------EPPAYDG-GSPILGYFIERKKKQSSRW 691
                 AP V EV       +W            +PP + G G+      +E      S W
Sbjct: 587  -HGEWAPGVLEVPIGQ--YHWGXEHHSSFPAACDPPVHRGWGAHPKPPLVEGWCSPGSLW 643

Query: 692  -----MRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPP 746
                 + + + L      E   + +   Y     A N  G SK  +  +  VP  +   P
Sbjct: 644  GEPTGIPVAYSLPPPLQIEKVDLRDEGIYTCA--ATNLAGESKREVALKVLVPPNIEPGP 701

Query: 747  ---TLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFT 803
                +L   SVT   +     PPD     G          +    W+     +  +    
Sbjct: 702  VNKAVLENASVTLECLASGVPPPDVSWFKG---------HQPVSSWMGVTVSVDGRVLRI 752

Query: 804  ITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEA 863
                 +DA  + R  A N AG++E +Y  +      +  PP+I +P  L    +  V   
Sbjct: 753  EQAQLSDAGSY-RCVASNVAGSTELRYGLR------VNVPPRITLPPSLPGPVL--VNTP 803

Query: 864  VNLVIPFQGKPRPELTWKKDGAEID-KNQINIRNSETDTIIFIRKAERSHSGKYDLQVKV 922
            V L     G P P L W KDG  +       ++      ++ +  A  S SG+Y      
Sbjct: 804  VRLTCNATGAPSPTLMWLKDGNPVSPAGTPGLQVFPGGRVLTLASARASDSGRYSCVAVS 863

Query: 923  DKFVETASIDIQIIDRPGPPQI----VKIEDVWGENVAL-----TWTPP-----KDDGNA 968
                +   + +Q+     PP I    + +  V  E+VAL        PP     KD    
Sbjct: 864  AVGEDRQDVVLQV---HMPPSILGEELNVSVVANESVALECQSHAMPPPVLSWWKDGRPL 920

Query: 969  AITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTK 1028
                     ADK  ++              +    + +  ++   + N  G SE      
Sbjct: 921  EPRPGVHLSADKALLQ--------------VDRADVWDAGHYTCEALNQAGRSE------ 960

Query: 1029 ESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIA---GYNATLNCSVRGNPKPKI 1085
                     K Y   V+       AP+F  PL  ++ +    G+  +L+C  RG P PKI
Sbjct: 961  ---------KHYNLNVW------VAPVF--PLRESHTLTVREGHPTSLSCECRGVPFPKI 1003

Query: 1086 TWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVKV 1145
            +W K+   +  +       +     L + +      GTY C+  N +G    + +LEV V
Sbjct: 1004 SWRKDGQPLPGEGAGLQHVSAVGRLLYLGQAQLAQEGTYTCECSNVVGNSSQDLQLEVHV 1063

Query: 1146 IAQ 1148
              Q
Sbjct: 1064 PPQ 1066



 Score = 94.7 bits (234), Expect = 4e-19
 Identities = 196/889 (22%), Positives = 331/889 (37%), Gaps = 129/889 (14%)

Query: 301  LADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTE- 359
            L +P   + W +NG    PS +      G  ++L ++  ++ D + Y   A ++  S E 
Sbjct: 1679 LGNPVPTISWLQNGLPFSPSPRLQVLEDG--QVLQVSTAEVADAASYMCVAENQAGSAEK 1736

Query: 360  ---LFVREPPIMVTKQLEDTTAYCGERVELECEV-SEDDANVKWFKNGEEIIPGPKSRYR 415
               L V+ PP +    LE  TA     V L C+V +  +  V W+K+ + +  G +    
Sbjct: 1737 LFTLRVQVPPRIAGLDLEQVTAILNSSVSLPCDVHAHPNPEVTWYKDSQALSLGEE---- 1792

Query: 416  IRVEGKKHILIIEGATKADAAEYS--VMTTGG--QSSAKLSVDLKPLKILTPLTDQT--- 468
            + +    H L +  A  +D+  Y+   +   G  Q   +LSV + P     P   Q    
Sbjct: 1793 VFLLPGTHTLQLGRARLSDSGMYTCEALNAAGRDQKLVQLSVLVPPAFRQAPRGPQDAVL 1852

Query: 469  VNLGKEICLKCEISENIPGK---WTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGD 525
            V +G +  L CE ++ +P     W K+G P+  + R + +  G+  +L I  A   D+G 
Sbjct: 1853 VRVGDKAVLSCE-TDALPEPTVTWYKDGQPLVLAQRTQALRGGQ--RLEIQEAQVSDKGL 1909

Query: 526  Y------VFAPDAYNVTLPAKVH-VIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEP 578
            Y      V        TL  +V    + PK          TV+ +AG+ L L   +SG P
Sbjct: 1910 YSCKVSNVAGEAVRTFTLTVQVPPTFENPKT--------ETVSQVAGSPLVLTCDVSGVP 1961

Query: 579  PPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIK 638
             P   W + D+  +E S      S      L +   +   +G Y    +N   EA     
Sbjct: 1962 APTVTWLK-DRMPVESSAVHGVVSR--GGRLQLSRLQPAQAGTYTCVAENTQAEARKDFV 2018

Query: 639  VKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDL 698
            V V+      VAP +   G     +  E    +G    L    + +      W++    L
Sbjct: 2019 VAVL------VAPRIRSSG-----VAREHHVLEGQEVRLDCEADGQPPPDVAWLKDGSPL 2067

Query: 699  CKETTFEPKKMIEGVAYEVRIFAVNAIGI-----SKPSMPSRPFVPLAVTSPPTLL---- 749
             ++     +  ++G +  ++    +  G        P+        + V  PPT+     
Sbjct: 2068 GQDMGPHLRFYLDGGSLVLKGLRASDAGAYTCVAHNPAGEDARLHTVNVLVPPTIKQGAD 2127

Query: 750  ---TVDSVTDTTVTM----RWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKF 802
               T+ S     VTM    R  PP H+     DG  L           ++ + L+  +  
Sbjct: 2128 GSGTLVSRPGELVTMVCPVRGSPPIHVSWLK-DGLPLP----------LSQRTLLHGSGH 2176

Query: 803  TITGLPT---DAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRR 859
            T+        DA IF  V A + AG ++  +  Q       ++ P +  P   +   +  
Sbjct: 2177 TLRISKVQLADAGIFTCV-AASPAGVADRNFTLQ-------VQVPPVLEPVEFQNDVVVV 2228

Query: 860  VGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQ 919
             G  V L    +G P P ++W KDG  +    +     E    + +       SG Y   
Sbjct: 2229 RGSLVELPCEARGVPLPLVSWMKDGEPLLSQSL-----EQGPSLQLEAVGAGDSGTYSCV 2283

Query: 920  VKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKAD 979
               +         + +++ P       IED  G+   L+ TP    G         Q   
Sbjct: 2284 AVSEAGEARRHFQLTVMEPP------HIEDS-GQPTELSLTP----GAPMELLCDAQGTP 2332

Query: 980  KKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKI 1039
            + ++ W       H+    +T L   N    RV      GL    T   ES   A + K 
Sbjct: 2333 QPNITW-------HKDGQALTRLE-NNSRATRVLRVRDAGLY---TCLAESPAGAIE-KS 2380

Query: 1040 YKNPVYEDFDF--SEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDD 1097
            ++  V    +      P F         +A     L CSV   P PKITW ++ + + +D
Sbjct: 2381 FRVRVQAPPNIVGPRGPRFV------VGLAPGQLVLECSVEAEPAPKITWHRDGIVLQED 2434

Query: 1098 PRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVKVI 1146
              +  F  +G   L+++  S  D G Y C A N  G+  +  ++E+  +
Sbjct: 2435 -AHTQFPERG-RFLQLQALSTADSGDYSCTARNAAGSTSVAFRVEIHTV 2481



 Score = 90.5 bits (223), Expect = 8e-18
 Identities = 193/910 (21%), Positives = 345/910 (37%), Gaps = 152/910 (16%)

Query: 302  ADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYV----TAGDEKCS 357
            A P   ++WYK+GQ + PS++   +  G  R+L I   Q++D   Y       AG++   
Sbjct: 1474 AVPPPTIRWYKDGQPVTPSSR--LQVLGEGRLLQIQPTQVSDSGRYLCVATNVAGEDDQD 1531

Query: 358  TELFVREPPIM-----------VTKQLEDTTAYCGERVE--------LECEVSE-DDANV 397
              + ++ PP+            +  + E+      E  E        L C+ +     ++
Sbjct: 1532 FNVLIQVPPMFQKVGDFSAAFEILSREEEARGGVTEYREIVENNPAYLYCDTNAIPPPDL 1591

Query: 398  KWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKP 457
             W++  + +  G +    + V     +L I      +A  YS   +       L  +   
Sbjct: 1592 TWYREDQPLSAGDE----VSVLQGGRVLQIPLVRAENAGRYSCKASNEVGEDWLHYE--- 1644

Query: 458  LKILTP----------LTDQTVNLGKEICLKCEISEN-IPG-KWTKNGLPVQESDRLKVV 505
            L +LTP          + + TVN    + L+C    N +P   W +NGLP   S RL+V+
Sbjct: 1645 LLVLTPPVILGDTEELVEEVTVNASSTVSLQCPALGNPVPTISWLQNGLPFSPSPRLQVL 1704

Query: 506  HKGRIHKLVIANALTEDEGDYVFAPD--AYNVTLPAKVHVIDPPKIILDGLDADNTVTVI 563
              G++  L ++ A   D   Y+   +  A +      + V  PP+I   GLD +  VT I
Sbjct: 1705 EDGQV--LQVSTAEVADAASYMCVAENQAGSAEKLFTLRVQVPPRIA--GLDLEQ-VTAI 1759

Query: 564  AGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYH 623
              + + L   +   P P+  W +  +A+  G         P + TL +  A   DSG+Y 
Sbjct: 1760 LNSSVSLPCDVHAHPNPEVTWYKDSQALSLGE---EVFLLPGTHTLQLGRARLSDSGMYT 1816

Query: 624  INLKNEAGEAHASIKVKVV------DFPDPPVAPTVTEVGDDWCIMNWEPPA-------- 669
                N AG     +++ V+        P  P    +  VGD   +++ E  A        
Sbjct: 1817 CEALNAAGRDQKLVQLSVLVPPAFRQAPRGPQDAVLVRVGDK-AVLSCETDALPEPTVTW 1875

Query: 670  YDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKM----IEGVAYE-VRIFAVNA 724
            Y  G P++   + ++ +      RL     +E     K +    +  VA E VR F +  
Sbjct: 1876 YKDGQPLV---LAQRTQALRGGQRLEI---QEAQVSDKGLYSCKVSNVAGEAVRTFTLT- 1928

Query: 725  IGISKPSMPSRPFVPLA--VTSPPTLLTVDSVTDTTVTMRW---RPPDHIGAAGLDGYVL 779
              +  P     P       V   P +LT D       T+ W   R P  + ++ + G   
Sbjct: 1929 --VQVPPTFENPKTETVSQVAGSPLVLTCDVSGVPAPTVTWLKDRMP--VESSAVHG--- 1981

Query: 780  EYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKE 839
                      +V+    +  ++      P  A  +  V     A A +         V  
Sbjct: 1982 ----------VVSRGGRLQLSRLQ----PAQAGTYTCVAENTQAEARKD-------FVVA 2020

Query: 840  IIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQ-INIRNSE 898
            ++  P+IR     ++ ++   G+ V L     G+P P++ W KDG+ + ++   ++R   
Sbjct: 2021 VLVAPRIRSSGVAREHHVLE-GQEVRLDCEADGQPPPDVAWLKDGSPLGQDMGPHLRFYL 2079

Query: 899  TDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVA-- 956
                + ++    S +G Y   V  +   E A   +  ++   PP I +  D  G  V+  
Sbjct: 2080 DGGSLVLKGLRASDAGAYTC-VAHNPAGEDAR--LHTVNVLVPPTIKQGADGSGTLVSRP 2136

Query: 957  ---LTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVF 1013
               +T   P   G+  I    ++      +   T++ H    +  I+++ + +   F   
Sbjct: 2137 GELVTMVCPV-RGSPPIHVSWLKDGLPLPLSQRTLL-HGSGHTLRISKVQLADAGIFTCV 2194

Query: 1014 SENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATL 1073
            + +  G++ D   T +  V          PV E  +F           +   + G    L
Sbjct: 2195 AASPAGVA-DRNFTLQVQV---------PPVLEPVEFQN---------DVVVVRGSLVEL 2235

Query: 1074 NCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLG 1133
             C  RG P P ++WMK+      +P       QG  +L++      D GTY C AV++ G
Sbjct: 2236 PCEARGVPLPLVSWMKD-----GEPLLSQSLEQGP-SLQLEAVGAGDSGTYSCVAVSEAG 2289

Query: 1134 TVEIECKLEV 1143
                  +L V
Sbjct: 2290 EARRHFQLTV 2299



 Score = 80.1 bits (196), Expect = 1e-14
 Identities = 189/910 (20%), Positives = 325/910 (35%), Gaps = 136/910 (14%)

Query: 302  ADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILF-INNCQMTDDSEYYVTAGDEKCSTE- 359
            A P   + W+K+G+ + P       H    + L  ++   + D   Y   A ++   +E 
Sbjct: 905  AMPPPVLSWWKDGRPLEPRPGV---HLSADKALLQVDRADVWDAGHYTCEALNQAGRSEK 961

Query: 360  ---LFVREPPIMVTKQLEDTTAYCGERVELECEV-SEDDANVKWFKNGEEIIPGPKSRYR 415
               L V   P+   ++    T   G    L CE        + W K+G+ + PG  +  +
Sbjct: 962  HYNLNVWVAPVFPLRESHTLTVREGHPTSLSCECRGVPFPKISWRKDGQPL-PGEGAGLQ 1020

Query: 416  IRVEGKKHILIIEGATKADAAEYSVMTTG--GQSSAKLSVDLK-PLKILTPL---TDQTV 469
              V     +L +  A  A    Y+   +   G SS  L +++  P +I  P    T  +V
Sbjct: 1021 -HVSAVGRLLYLGQAQLAQEGTYTCECSNVVGNSSQDLQLEVHVPPQIAGPREPPTQVSV 1079

Query: 470  NLGKEICLKCEISENIPGK--WTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYV 527
                   L+C  +   P    W ++G PV     L++ ++G+   L +  A     G Y 
Sbjct: 1080 VQDGVATLECNATGKPPPTVTWERDGQPVGAELGLQLQNQGQ--SLHVERAQAAHTGRYS 1137

Query: 528  FAPD--AYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWS 585
               +  A       ++ V+ PP++I D LD    +T    + L L     G PPP   W 
Sbjct: 1138 CVAENLAGRAERKFELSVLVPPELIGD-LDPLTNITAALHSPLTLLCEAMGIPPPAIRWF 1196

Query: 586  RGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFP 645
            RG++ +  G     T        L +   +  DSG+Y     NEAGEA  +  V+V+   
Sbjct: 1197 RGEEPVSPGED---TYLLAGGWMLKMTQTQEQDSGLYSCLASNEAGEARRNFSVEVL--- 1250

Query: 646  DPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFE 705
               V P++     +  I        DG +  L   +    +    W +    L +     
Sbjct: 1251 ---VPPSIENEDLEEVI-----KVLDGQTAHLMCNVTGHPQPKLTWFKDGRPLARGDAHH 1302

Query: 706  PKKMIEGVAYEV-----------RIFAVNAIGISKPSMPSRPFVPLAVTSPPTLL-TVDS 753
                 +GV  +V              A NA+G             L+V   PT+L   + 
Sbjct: 1303 ISP--DGVLLQVLQANLSSAGHYSCIAANAVG------EKTKHFQLSVLLAPTILGGAED 1354

Query: 754  VTDTTVTMRWRPPDHIGAAGL-----------DGYVLE-----YCFEGTEDWIVANKDLI 797
              D  VT+    P  +    L           DG   E         GT    + N    
Sbjct: 1355 SADEEVTVTVNNPISLICEALAFPSPNITWMKDGAPFEASRNIQLLPGTHGLQILNAQKE 1414

Query: 798  DKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYI 857
            D  ++T                 N  G +   Y+       E++ PP I     L +  +
Sbjct: 1415 DAGQYTCV-------------VTNELGEAVKNYH------VEVLIPPSISKDDPLGEVGV 1455

Query: 858  RRVGEAVNLVIPFQ----GKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHS 913
            + V   VN  +  +      P P + W KDG  +  +   ++      ++ I+  + S S
Sbjct: 1456 KEVKTKVNSTLTLECESWAVPPPTIRWYKDGQPVTPSS-RLQVLGEGRLLQIQPTQVSDS 1514

Query: 914  GKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGY 973
            G+Y L V  +   E    D  ++ +  PP   K+ D    + A      +++    +T  
Sbjct: 1515 GRY-LCVATNVAGEDDQ-DFNVLIQV-PPMFQKVGDF---SAAFEILSREEEARGGVT-- 1566

Query: 974  TIQKADKKSMEWFTVIEH-----YHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTK 1028
                      E+  ++E+     Y  T+A     +        + + +   + +   + +
Sbjct: 1567 ----------EYREIVENNPAYLYCDTNAIPPPDLTWYREDQPLSAGDEVSVLQGGRVLQ 1616

Query: 1029 ESAVIARDGKIY----KNPVYEDFDFSEAPMFTQPLV---------NTYAIAGYNATLNC 1075
               V A +   Y     N V ED+   E  + T P++              A    +L C
Sbjct: 1617 IPLVRAENAGRYSCKASNEVGEDWLHYELLVLTPPVILGDTEELVEEVTVNASSTVSLQC 1676

Query: 1076 SVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTV 1135
               GNP P I+W++N +     PR ++  +  V  L++      D  +Y C A N  G+ 
Sbjct: 1677 PALGNPVPTISWLQNGLPFSPSPRLQVLEDGQV--LQVSTAEVADAASYMCVAENQAGSA 1734

Query: 1136 EIECKLEVKV 1145
            E    L V+V
Sbjct: 1735 EKLFTLRVQV 1744



 Score = 77.8 bits (190), Expect = 6e-14
 Identities = 180/869 (20%), Positives = 308/869 (35%), Gaps = 107/869 (12%)

Query: 304  PKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTA----GDEKCSTE 359
            P + V W K+G  +  S + +    G    L I+  Q+ D   +   A    G    +  
Sbjct: 2150 PPIHVSWLKDGLPLPLSQRTLLHGSG--HTLRISKVQLADAGIFTCVAASPAGVADRNFT 2207

Query: 360  LFVREPPIMVTKQLE-DTTAYCGERVELECEVSEDDAN-VKWFKNGEEIIP-----GPKS 412
            L V+ PP++   + + D     G  VEL CE        V W K+GE ++      GP  
Sbjct: 2208 LQVQVPPVLEPVEFQNDVVVVRGSLVELPCEARGVPLPLVSWMKDGEPLLSQSLEQGPS- 2266

Query: 413  RYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPL-------- 464
                        L +E     D+  YS +       A+    L    ++ P         
Sbjct: 2267 ------------LQLEAVGAGDSGTYSCVAVSEAGEARRHFQLT---VMEPPHIEDSGQP 2311

Query: 465  TDQTVNLGKEICLKCEISENIPGK---WTKNGLPVQESDRLKVVHKGRIHKLVIANALTE 521
            T+ ++  G  + L C+ ++  P     W K+G   Q   RL+  +  R  +++       
Sbjct: 2312 TELSLTPGAPMELLCD-AQGTPQPNITWHKDG---QALTRLE--NNSRATRVL----RVR 2361

Query: 522  DEGDYVFAPD--AYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPP 579
            D G Y    +  A  +    +V V  PP I+  G      V  +A  +L LE  +  EP 
Sbjct: 2362 DAGLYTCLAESPAGAIEKSFRVRVQAPPNIV--GPRGPRFVVGLAPGQLVLECSVEAEPA 2419

Query: 580  PKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKV 639
            PK  W R    + E +    T+       L +      DSG Y    +N AG    + +V
Sbjct: 2420 PKITWHRDGIVLQEDA---HTQFPERGRFLQLQALSTADSGDYSCTARNAAGSTSVAFRV 2476

Query: 640  KVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDG-GSPILGYFIERKKKQSSRWMRLNFDL 698
            ++   P     P    V  +   +   P   DG  +P++ +   RK +         F++
Sbjct: 2477 EIHTVPTIRSGPPAVNVSVNQTALL--PCQADGVPAPLVSW---RKDRVPLDPRSPRFEI 2531

Query: 699  CKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTT 758
              E +   + ++   A      A N+ G  +     R   P A+   P+ LT+ + T   
Sbjct: 2532 LPEGSLRIQPVLAQDAGHYLCLASNSAGSDRQGRDLRVLEPPAIAPSPSNLTLTAHTPAL 2591

Query: 759  VTMRWR-PPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRV 817
            +       P  +     DG  L++  +     ++ +  L+     T  G P D+  F  V
Sbjct: 2592 LPCEASGSPKPLVVWWKDGQKLDFRLQQGAYRLLPSNALL----LTAPG-PQDSAQFECV 2646

Query: 818  KAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPE 877
             + N  G +  + Y   + V     PP I   +     +   +   V L     G P P 
Sbjct: 2647 VS-NEVGEAH-RLYQVTVHV-----PPTIADDQ---TDFTVTMMAPVVLTCHSTGIPAPT 2696

Query: 878  LTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIID 937
            ++W K GA++       R S +  +  I +A   H+G+Y    +    V    + + +  
Sbjct: 2697 VSWSKAGAQLGARGSGYRVSPSGALE-IGQALPIHAGRYTCSARNSAGVAHKHVFLTVQA 2755

Query: 938  RPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSA 997
             P    +  +     E   L    P +         T QK            E  +  + 
Sbjct: 2756 SPVVKPLPSVVRAVAEEEVLL---PCEASGIPRPTITWQK------------EGLNVATG 2800

Query: 998  TITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFT 1057
              T+++ G +      S    G           + + +   + + P          P+  
Sbjct: 2801 VSTQVLPGGQLRIAHASPEDAGNYLCIAKNSAGSAMGKTRLVVQVP----------PVIE 2850

Query: 1058 QPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPS 1117
              L +     G +A L C  RG+P+P ITW K+   +        F+ Q    L ++   
Sbjct: 2851 NGLPDLSTTEGSHAFLPCKARGSPEPNITWDKDGQPV--SGAEGKFTIQPSGELLVKNLE 2908

Query: 1118 PYDGGTYCCKAVNDLGTVEIECKLEVKVI 1146
              D GTY C A N +G       L + V+
Sbjct: 2909 GQDAGTYTCTAENAVGRARRRVHLTILVL 2937



 Score = 75.5 bits (184), Expect = 3e-13
 Identities = 193/914 (21%), Positives = 339/914 (37%), Gaps = 140/914 (15%)

Query: 273  EKKSAAFAKILDPAY-QVDKGGRVRFVVELAD-----------PKLEVKWYKNGQEIRPS 320
            ++K    + ++ PA+ Q  +G +   +V + D           P+  V WYK+GQ +  +
Sbjct: 1826 DQKLVQLSVLVPPAFRQAPRGPQDAVLVRVGDKAVLSCETDALPEPTVTWYKDGQPLVLA 1885

Query: 321  TKYIFEHKGCQRILFINNCQMTDDSEYYV----TAGDEKCSTELFVREPPIMVTKQLEDT 376
             +     +G QR L I   Q++D   Y       AG+   +  L V+ PP     + E  
Sbjct: 1886 QR-TQALRGGQR-LEIQEAQVSDKGLYSCKVSNVAGEAVRTFTLTVQVPPTFENPKTETV 1943

Query: 377  TAYCGERVELECEVSEDDA-NVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADA 435
            +   G  + L C+VS   A  V W K+   +    +S     V  +   L +     A A
Sbjct: 1944 SQVAGSPLVLTCDVSGVPAPTVTWLKDRMPV----ESSAVHGVVSRGGRLQLSRLQPAQA 1999

Query: 436  AEYSVMTTGGQSSAK----LSVDLKP-LKILTPLTDQTVNLGKEICLKCEISENIPGK-- 488
              Y+ +    Q+ A+    ++V + P ++      +  V  G+E+ L CE     P    
Sbjct: 2000 GTYTCVAENTQAEARKDFVVAVLVAPRIRSSGVAREHHVLEGQEVRLDCEADGQPPPDVA 2059

Query: 489  WTKNGLPVQES--DRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVT-LPAKVHVID 545
            W K+G P+ +     L+    G    LV+      D G Y     A+N     A++H ++
Sbjct: 2060 WLKDGSPLGQDMGPHLRFYLDGG--SLVLKGLRASDAGAYTCV--AHNPAGEDARLHTVN 2115

Query: 546  P--PKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSR-------GDKAIMEGSG 596
               P  I  G D   T+    G  + +  P+ G PP    W +         + ++ GSG
Sbjct: 2116 VLVPPTIKQGADGSGTLVSRPGELVTMVCPVRGSPPIHVSWLKDGLPLPLSQRTLLHGSG 2175

Query: 597  RIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEV 656
                       TL I   +  D+G++     + AG A  +  ++V     PPV   V E 
Sbjct: 2176 H----------TLRISKVQLADAGIFTCVAASPAGVADRNFTLQV---QVPPVLEPV-EF 2221

Query: 657  GDDWCIMNW---EPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFE-PKKMIEG 712
             +D  ++     E P    G P+              WM+    L  ++  + P   +E 
Sbjct: 2222 QNDVVVVRGSLVELPCEARGVPL----------PLVSWMKDGEPLLSQSLEQGPSLQLEA 2271

Query: 713  VAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAA 772
            V         + + +S+     R F  L V  PP +      T+ ++T          A 
Sbjct: 2272 VG-AGDSGTYSCVAVSEAGEARRHF-QLTVMEPPHIEDSGQPTELSLTPGAPMELLCDAQ 2329

Query: 773  GLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYS 832
            G     + +  +G      A   L + ++ T      DA ++  + A + AGA E  +  
Sbjct: 2330 GTPQPNITWHKDGQ-----ALTRLENNSRATRVLRVRDAGLYTCL-AESPAGAIEKSFRV 2383

Query: 833  QPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQI 892
            +      +  PP I  PR  +       G+ V L    + +P P++TW +DG  + ++  
Sbjct: 2384 R------VQAPPNIVGPRGPRFVVGLAPGQLV-LECSVEAEPAPKITWHRDGIVLQED-A 2435

Query: 893  NIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQI----IDRPGPPQIVKIE 948
            + +  E    + ++    + SG Y    +      + +  ++I      R GPP +    
Sbjct: 2436 HTQFPERGRFLQLQALSTADSGDYSCTARNAAGSTSVAFRVEIHTVPTIRSGPPAV---- 2491

Query: 949  DVWGENVALTWT---PPKDDG-NAAITGYTIQKA--DKKSMEWFTVIEHYHRTSATITEL 1002
                 NV++  T   P + DG  A +  +   +   D +S  +    E     S  I  +
Sbjct: 2492 -----NVSVNQTALLPCQADGVPAPLVSWRKDRVPLDPRSPRF----EILPEGSLRIQPV 2542

Query: 1003 VIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVN 1062
            +  +  ++   + N  G               R G+        D    E P       N
Sbjct: 2543 LAQDAGHYLCLASNSAGSD-------------RQGR--------DLRVLEPPAIAPSPSN 2581

Query: 1063 TYAIAGYNATLNCSVRGNPKPKITWMKNKVAI---VDDPRYRMFSNQGVCTLEIRKPSPY 1119
                A   A L C   G+PKP + W K+   +   +    YR+  +     L +  P P 
Sbjct: 2582 LTLTAHTPALLPCEASGSPKPLVVWWKDGQKLDFRLQQGAYRLLPSN---ALLLTAPGPQ 2638

Query: 1120 DGGTYCCKAVNDLG 1133
            D   + C   N++G
Sbjct: 2639 DSAQFECVVSNEVG 2652



 Score = 74.3 bits (181), Expect = 6e-13
 Identities = 93/371 (25%), Positives = 155/371 (41%), Gaps = 35/371 (9%)

Query: 304  PKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYV-----TAGDEKCST 358
            P+  + W K G  +           G  RI   +     +D+  Y+     +AG     T
Sbjct: 2784 PRPTITWQKEGLNVATGVSTQVLPGGQLRIAHAS----PEDAGNYLCIAKNSAGSAMGKT 2839

Query: 359  ELFVREPPIMVTKQLEDTTAYCGERVELECEV-SEDDANVKWFKNGEEIIPGPKSRYRIR 417
             L V+ PP+ +   L D +   G    L C+     + N+ W K+G+ +  G + ++ I+
Sbjct: 2840 RLVVQVPPV-IENGLPDLSTTEGSHAFLPCKARGSPEPNITWDKDGQPV-SGAEGKFTIQ 2897

Query: 418  VEGKKHILIIEGATKADAAEYSVMTTG--GQSSAKLSVDLKPLKILTPLT-DQTVNLGKE 474
              G+  +  +EG    DA  Y+       G++  ++ + +  L + T L  D+++ LG  
Sbjct: 2898 PSGELLVKNLEGQ---DAGTYTCTAENAVGRARRRVHLTILVLPVFTTLPGDRSLRLGDR 2954

Query: 475  ICLKCEISENIPGK--WTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYV-FAPD 531
            + L+C    +   +  WT N  PV E     V  +     L  A    ED G YV +A +
Sbjct: 2955 LWLRCAARGSPTPRIGWTVNDRPVTEG----VSEQDGGSTLQRAAVSREDSGTYVCWAEN 3010

Query: 532  AYNVTLPAK-VHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKA 590
                T     VHV + P  +L G +A + +    G  ++L+  + G+P P   W + D  
Sbjct: 3011 RVGRTQAVSFVHVKEAP--VLQG-EAFSYLVEPVGGSIQLDCVVRGDPVPDIHWIK-DGL 3066

Query: 591  IMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVA 650
             + GS          + +L I   ERDD+G Y    +NE G A   + + +   P   V 
Sbjct: 3067 PLRGS---HLRHQLQNGSLTIHRTERDDAGRYQCLAENEMGVAKKVVILVLQSAPVFQVE 3123

Query: 651  PTVTEV--GDD 659
            P    V  GDD
Sbjct: 3124 PQDMTVRSGDD 3134



 Score = 68.2 bits (165), Expect = 4e-11
 Identities = 176/875 (20%), Positives = 326/875 (37%), Gaps = 141/875 (16%)

Query: 304  PKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTELFVR 363
            P+  + W+K+GQ +      +  +    R+L + +  +            EK S  + V+
Sbjct: 2332 PQPNITWHKDGQALTR----LENNSRATRVLRVRDAGLYTCLAESPAGAIEK-SFRVRVQ 2386

Query: 364  EPPIMV-TKQLEDTTAYCGERVELECEVSEDDA-NVKWFKNGEEIIPGPKSRYRIRVEGK 421
             PP +V  +           ++ LEC V  + A  + W ++G  +     +++  R    
Sbjct: 2387 APPNIVGPRGPRFVVGLAPGQLVLECSVEAEPAPKITWHRDGIVLQEDAHTQFPER---- 2442

Query: 422  KHILIIEGATKADAAEYS--VMTTGGQSSAKLSVDLKPLKILT---PLTDQTVNLGKEIC 476
               L ++  + AD+ +YS       G +S    V++  +  +    P  + +VN  +   
Sbjct: 2443 GRFLQLQALSTADSGDYSCTARNAAGSTSVAFRVEIHTVPTIRSGPPAVNVSVN--QTAL 2500

Query: 477  LKCEISENIPG---KWTKNGLPVQ-ESDRLKVVHKGRIHKLVIANALTEDEGDYVF--AP 530
            L C+ ++ +P     W K+ +P+   S R +++ +G +    I   L +D G Y+   + 
Sbjct: 2501 LPCQ-ADGVPAPLVSWRKDRVPLDPRSPRFEILPEGSLR---IQPVLAQDAGHYLCLASN 2556

Query: 531  DAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRG--- 587
             A +      + V++PP I      + + +T+ A     L    SG P P  +W +    
Sbjct: 2557 SAGSDRQGRDLRVLEPPAIA----PSPSNLTLTAHTPALLPCEASGSPKPLVVWWKDGQK 2612

Query: 588  -DKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKV----- 641
             D  + +G+ R+       S+ L++      DS  +   + NE GEAH   +V V     
Sbjct: 2613 LDFRLQQGAYRLLP-----SNALLLTAPGPQDSAQFECVVSNEVGEAHRLYQVTVHVPPT 2667

Query: 642  -----VDFPDPPVAPTVT---EVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMR 693
                  DF    +AP V      G     ++W       G+   GY   R     +  + 
Sbjct: 2668 IADDQTDFTVTMMAPVVLTCHSTGIPAPTVSWSKAGAQLGARGSGY---RVSPSGALEIG 2724

Query: 694  LNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDS 753
                +         +   GVA++     V A  + KP     P V  AV     LL  ++
Sbjct: 2725 QALPIHAGRYTCSARNSAGVAHKHVFLTVQASPVVKP----LPSVVRAVAEEEVLLPCEA 2780

Query: 754  VTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKI 813
                  T+ W+      A G+   VL     G +  I                 P DA  
Sbjct: 2781 SGIPRPTITWQKEGLNVATGVSTQVL----PGGQLRIA-------------HASPEDAGN 2823

Query: 814  FVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGK 873
            ++ + A N+AG++  K        + +++ P + I   L        G    L    +G 
Sbjct: 2824 YLCI-AKNSAGSAMGK-------TRLVVQVPPV-IENGLPDLSTTE-GSHAFLPCKARGS 2873

Query: 874  PRPELTWKKDGAEID--KNQINIRNSETDTIIFIRKAERSHSGKYDLQVK--VDKFVETA 929
            P P +TW KDG  +   + +  I+ S     + ++  E   +G Y    +  V +     
Sbjct: 2874 PEPNITWDKDGQPVSGAEGKFTIQPSGE---LLVKNLEGQDAGTYTCTAENAVGRARRRV 2930

Query: 930  SIDIQII----DRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEW 985
             + I ++      PG   +   + +W    A     P+        G+T+   D+   E 
Sbjct: 2931 HLTILVLPVFTTLPGDRSLRLGDRLWLRCAARGSPTPR-------IGWTVN--DRPVTEG 2981

Query: 986  FTVIEHYHRTSATITELVIGNE--YYFRVFSENMCGLSEDATM--TKESAVIARDGKIYK 1041
             +  +      +T+    +  E    +  ++EN  G ++  +    KE+ V+        
Sbjct: 2982 VSEQD----GGSTLQRAAVSREDSGTYVCWAENRVGRTQAVSFVHVKEAPVLQG------ 3031

Query: 1042 NPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYR 1101
                E F +   P+            G +  L+C VRG+P P I W+K+ + +       
Sbjct: 3032 ----EAFSYLVEPV------------GGSIQLDCVVRGDPVPDIHWIKDGLPLRGSHLRH 3075

Query: 1102 MFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVE 1136
               N    +L I +    D G Y C A N++G  +
Sbjct: 3076 QLQNG---SLTIHRTERDDAGRYQCLAENEMGVAK 3107



 Score = 63.9 bits (154), Expect = 8e-10
 Identities = 172/826 (20%), Positives = 300/826 (36%), Gaps = 121/826 (14%)

Query: 351  AGDEKCSTELFVREPP-IMVTKQLEDTTAYCGERVELECEVS-EDDANVKWFKNGEEIIP 408
            AG+ +   +L V EPP I  + Q  + +   G  +EL C+       N+ W K+G+ +  
Sbjct: 2288 AGEARRHFQLTVMEPPHIEDSGQPTELSLTPGAPMELLCDAQGTPQPNITWHKDGQALTR 2347

Query: 409  GPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLK---PLKILTPLT 465
               +    RV   +           DA  Y+ +      + + S  ++   P  I+ P  
Sbjct: 2348 LENNSRATRVLRVR-----------DAGLYTCLAESPAGAIEKSFRVRVQAPPNIVGPRG 2396

Query: 466  DQ-TVNLGK-EICLKCEISENIPGK--WTKNGLPVQESDRLKVVHKGRIHKLVIANALTE 521
             +  V L   ++ L+C +      K  W ++G+ +QE    +   +GR  +L   +  T 
Sbjct: 2397 PRFVVGLAPGQLVLECSVEAEPAPKITWHRDGIVLQEDAHTQFPERGRFLQLQALS--TA 2454

Query: 522  DEGDYVF----APDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGE 577
            D GDY      A  + +V    ++H +     I  G  A   V V       L     G 
Sbjct: 2455 DSGDYSCTARNAAGSTSVAFRVEIHTVPT---IRSGPPA---VNVSVNQTALLPCQADGV 2508

Query: 578  PPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASI 637
            P P   W R D+  ++     R E  P+ S  +  +  +D +G Y     N AG      
Sbjct: 2509 PAPLVSW-RKDRVPLDPRSP-RFEILPEGSLRIQPVLAQD-AGHYLCLASNSAGSDRQGR 2565

Query: 638  KVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFD 697
             ++V++   P +AP+ + +          P    G    L  + +  +K   R  +  + 
Sbjct: 2566 DLRVLE--PPAIAPSPSNLTLTAHTPALLPCEASGSPKPLVVWWKDGQKLDFRLQQGAYR 2623

Query: 698  LCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDT 757
            L               + +      N +G       +     + V  PPT+   D  TD 
Sbjct: 2624 LLPSNALLLTAPGPQDSAQFECVVSNEVG------EAHRLYQVTVHVPPTI--ADDQTDF 2675

Query: 758  TVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITG--LPTDAKIFV 815
            TVTM         + G+    + +   G +     +   +  +     G  LP  A  + 
Sbjct: 2676 TVTMMAPVVLTCHSTGIPAPTVSWSKAGAQLGARGSGYRVSPSGALEIGQALPIHAGRYT 2735

Query: 816  RVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEA-VNLVIPFQGKP 874
               A N+AG +  K+    +    +++P    +P     + +R V E  V L     G P
Sbjct: 2736 -CSARNSAGVAH-KHVFLTVQASPVVKP----LP-----SVVRAVAEEEVLLPCEASGIP 2784

Query: 875  RPELTWKKDGAEIDKN---------QINIRNSETDT----IIFIRKAERSHSGKYDLQVK 921
            RP +TW+K+G  +            Q+ I ++  +     +   + +  S  GK  L V+
Sbjct: 2785 RPTITWQKEGLNVATGVSTQVLPGGQLRIAHASPEDAGNYLCIAKNSAGSAMGKTRLVVQ 2844

Query: 922  VDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKK 981
            V   +E    D+   +  G    +  +        +TW       + A   +TIQ +   
Sbjct: 2845 VPPVIENGLPDLSTTE--GSHAFLPCKARGSPEPNITWDKDGQPVSGAEGKFTIQPSG-- 2900

Query: 982  SMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDA---TMTKESAVIARDGK 1038
                               EL++          +N+ G  +DA   T T E+AV     +
Sbjct: 2901 -------------------ELLV----------KNLEG--QDAGTYTCTAENAVGRARRR 2929

Query: 1039 IYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDP 1098
            ++   +         P+FT    +     G    L C+ RG+P P+I W  N   + +  
Sbjct: 2930 VHLTILV-------LPVFTTLPGDRSLRLGDRLWLRCAARGSPTPRIGWTVNDRPVTEG- 2981

Query: 1099 RYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVK 1144
               +    G  TL+    S  D GTY C A N +G  +    + VK
Sbjct: 2982 ---VSEQDGGSTLQRAAVSREDSGTYVCWAENRVGRTQAVSFVHVK 3024



 Score = 48.9 bits (115), Expect = 3e-05
 Identities = 81/344 (23%), Positives = 133/344 (38%), Gaps = 31/344 (9%)

Query: 304  PKLEVKWYKNGQEIRPST-KYIFEHKGCQRILFINNCQMTDDSEYYVTA----GDEKCST 358
            P+  + W K+GQ +  +  K+  +  G    L + N +  D   Y  TA    G  +   
Sbjct: 2874 PEPNITWDKDGQPVSGAEGKFTIQPSG---ELLVKNLEGQDAGTYTCTAENAVGRARRRV 2930

Query: 359  ELFVREPPIMVTKQLEDTTAYCGERVELECEV-SEDDANVKWFKNGEEIIPGPKSRYRIR 417
             L +   P+  T    D +   G+R+ L C         + W  N   +  G   +    
Sbjct: 2931 HLTILVLPVFTTLP-GDRSLRLGDRLWLRCAARGSPTPRIGWTVNDRPVTEGVSEQDGGS 2989

Query: 418  VEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILT--PLTDQTVNLGKEI 475
               +  +   +  T    AE  V    G++ A   V +K   +L     +     +G  I
Sbjct: 2990 TLQRAAVSREDSGTYVCWAENRV----GRTQAVSFVHVKEAPVLQGEAFSYLVEPVGGSI 3045

Query: 476  CLKCEI-SENIPG-KWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDY-VFAPDA 532
             L C +  + +P   W K+GLP++ S     +  G    L I     +D G Y   A + 
Sbjct: 3046 QLDCVVRGDPVPDIHWIKDGLPLRGSHLRHQLQNG---SLTIHRTERDDAGRYQCLAENE 3102

Query: 533  YNVTLPAKVHVIDP-PKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAI 591
              V     + V+   P   ++  D    +TV +G+ + L    +GEP P   W +  +  
Sbjct: 3103 MGVAKKVVILVLQSAPVFQVEPQD----MTVRSGDDVALRCQATGEPTPTIEWLQAGQP- 3157

Query: 592  MEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHA 635
            +  S R+RT   PD S L ++  E  D+G Y     N  G A A
Sbjct: 3158 LRASRRLRT--LPDGS-LWLENVETGDAGTYDCVAHNLLGSATA 3198



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 92/380 (24%), Positives = 141/380 (37%), Gaps = 58/380 (15%)

Query: 302  ADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTELF 361
            A+P  ++ W+++G  ++      F  +G  R L +      D  +Y  TA +   ST + 
Sbjct: 2416 AEPAPKITWHRDGIVLQEDAHTQFPERG--RFLQLQALSTADSGDYSCTARNAAGSTSVA 2473

Query: 362  ----------VREPPIMVTKQLEDTTAYCGERVELECEVSEDDAN-VKWFKNGEEIIPGP 410
                      +R  P  V   +  T         L C+     A  V W K+   + P  
Sbjct: 2474 FRVEIHTVPTIRSGPPAVNVSVNQTAL-------LPCQADGVPAPLVSWRKDRVPLDPR- 2525

Query: 411  KSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLK---ILTPLTDQ 467
              R+ I  EG    L I+     DA  Y  + +    S +   DL+ L+   I    ++ 
Sbjct: 2526 SPRFEILPEGS---LRIQPVLAQDAGHYLCLASNSAGSDRQGRDLRVLEPPAIAPSPSNL 2582

Query: 468  TVNLGKEICLKCEISENIPGK--WTKNGLPVQ-----------ESDRLKVVHKGRIHKLV 514
            T+       L CE S +      W K+G  +             S+ L +   G      
Sbjct: 2583 TLTAHTPALLPCEASGSPKPLVVWWKDGQKLDFRLQQGAYRLLPSNALLLTAPGPQDSAQ 2642

Query: 515  IANALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPI 574
                ++ + G+   A   Y VT    VHV  PP I  D    D TVT++A   + L    
Sbjct: 2643 FECVVSNEVGE---AHRLYQVT----VHV--PPTIADD--QTDFTVTMMA--PVVLTCHS 2689

Query: 575  SGEPPPKAMWSR-GDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEA 633
            +G P P   WS+ G +    GSG         S  L I  A    +G Y  + +N AG A
Sbjct: 2690 TGIPAPTVSWSKAGAQLGARGSGY----RVSPSGALEIGQALPIHAGRYTCSARNSAGVA 2745

Query: 634  HASIKVKVVDFPDPPVAPTV 653
            H  + + V   P     P+V
Sbjct: 2746 HKHVFLTVQASPVVKPLPSV 2765



 Score = 43.9 bits (102), Expect = 9e-04
 Identities = 26/76 (34%), Positives = 36/76 (47%), Gaps = 11/76 (14%)

Query: 1075 CSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLE-----IRKPSPYDGGTYCCKAV 1129
            C   G PKP++TW K   +   +P   +    GV  LE     +   SP D G Y C+A 
Sbjct: 24   CGTHGTPKPQVTWRKGPSS---EP---LHGQPGVAVLEEGSLFLASVSPADSGDYECQAT 77

Query: 1130 NDLGTVEIECKLEVKV 1145
            N++G+     KL V V
Sbjct: 78   NEVGSTSRRAKLVVYV 93



 Score = 35.4 bits (80), Expect = 0.31
 Identities = 28/92 (30%), Positives = 44/92 (47%), Gaps = 7/92 (7%)

Query: 495 PVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAP--DAYNVTLPAKVHVIDPPKIILD 552
           P+     + V+ +G    L +A+    D GDY      +  + +  AK+ V  PP I  D
Sbjct: 44  PLHGQPGVAVLEEG---SLFLASVSPADSGDYECQATNEVGSTSRRAKLVVYVPPSIRED 100

Query: 553 GLDADNTVTVIAGNKLRLEIPISGEPPPKAMW 584
           G  A+  V+ +AG  L LE   +G P P+ +W
Sbjct: 101 GRKAN--VSGMAGQSLTLECDANGFPVPEIVW 130



 Score = 35.0 bits (79), Expect = 0.41
 Identities = 23/96 (23%), Positives = 43/96 (44%), Gaps = 4/96 (4%)

Query: 546 PPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPD 605
           PP ++  G  A   V  +AG  + L+   SG P P+  W++  + ++ G   ++ +   D
Sbjct: 215 PPSVL--GAGAAQEVLGLAGADVELQCWTSGVPTPQVEWTKDRQPVLPGGPHLQVQE--D 270

Query: 606 SSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKV 641
              L I  +   D G Y     + AG+     +++V
Sbjct: 271 GQVLRITGSHVGDEGRYQCVAFSPAGQQARDFQLRV 306



 Score = 35.0 bits (79), Expect = 0.41
 Identities = 25/92 (27%), Positives = 37/92 (40%), Gaps = 3/92 (3%)

Query: 1053 APMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLE 1112
            AP+F     +    +G +  L C   G P P I W++    +    R R   +    +L 
Sbjct: 3117 APVFQVEPQDMTVRSGDDVALRCQATGEPTPTIEWLQAGQPLRASRRLRTLPDG---SLW 3173

Query: 1113 IRKPSPYDGGTYCCKAVNDLGTVEIECKLEVK 1144
            +      D GTY C A N LG+      L V+
Sbjct: 3174 LENVETGDAGTYDCVAHNLLGSATARAFLVVR 3205



 Score = 32.3 bits (72), Expect = 2.7
 Identities = 25/104 (24%), Positives = 52/104 (50%), Gaps = 7/104 (6%)

Query: 857  IRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKY 916
            +  VG ++ L    +G P P++ W KDG  +  +  ++R+   +  + I + ER  +G+Y
Sbjct: 3038 VEPVGGSIQLDCVVRGDPVPDIHWIKDGLPLRGS--HLRHQLQNGSLTIHRTERDDAGRY 3095

Query: 917  DLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVW---GENVAL 957
              Q   +  +  A   + ++ +  P   V+ +D+    G++VAL
Sbjct: 3096 --QCLAENEMGVAKKVVILVLQSAPVFQVEPQDMTVRSGDDVAL 3137



 Score = 32.0 bits (71), Expect = 3.5
 Identities = 12/29 (41%), Positives = 17/29 (58%)

Query: 1062 NTYAIAGYNATLNCSVRGNPKPKITWMKN 1090
            N   +AG + TL C   G P P+I W+K+
Sbjct: 105  NVSGMAGQSLTLECDANGFPVPEIVWLKD 133



 Score = 31.6 bits (70), Expect = 4.5
 Identities = 20/78 (25%), Positives = 32/78 (41%), Gaps = 1/78 (1%)

Query: 1066 IAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYC 1125
            +AG +  L C   G P P++ W K++  ++    +      G   L I      D G Y 
Sbjct: 230  LAGADVELQCWTSGVPTPQVEWTKDRQPVLPGGPHLQVQEDGQ-VLRITGSHVGDEGRYQ 288

Query: 1126 CKAVNDLGTVEIECKLEV 1143
            C A +  G    + +L V
Sbjct: 289  CVAFSPAGQQARDFQLRV 306


>gi|4506569 roundabout 1 isoform a [Homo sapiens]
          Length = 1651

 Score =  105 bits (261), Expect = 3e-22
 Identities = 126/476 (26%), Positives = 180/476 (37%), Gaps = 65/476 (13%)

Query: 304 PKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGD------EKCS 357
           P+  + W K+G  +    + I    G   I +        D+  YV  G       E   
Sbjct: 198 PEPTISWKKDGSPLDDKDERITIRGGKLMITYTRK----SDAGKYVCVGTNMVGERESEV 253

Query: 358 TELFVREPPIMVTKQLEDTTAYCGERVELECEVSEDDA-NVKWFKNGEEIIPGPKSRYRI 416
            EL V E P  V K+  +      +  E +CE   D    V+W K+  E+   PKSRY I
Sbjct: 254 AELTVLERPSFV-KRPSNLAVTVDDSAEFKCEARGDPVPTVRWRKDDGEL---PKSRYEI 309

Query: 417 RVEGKKHILIIEGATKADAAEYSV----MTTGGQSSAKLSVDLKPLKILTPLTDQTVNLG 472
           R +   H L I   T  D   Y+     M    ++SA L+V   P  ++ P  DQ V LG
Sbjct: 310 RDD---HTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQEPPHFVVKP-RDQVVALG 365

Query: 473 KEICLKCEISENIPGK--WTKNGL--------PVQESDRLKVVHKGRIHKLVIANALTED 522
           + +  +CE + N      W + G         P Q S R  V   G    L I N    D
Sbjct: 366 RTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTG---DLTITNVQRSD 422

Query: 523 EGDYVFAP--DAYNVTLPAKVHVID-----PPKIILDGLDADNTVTVIAGNKLRLEIPIS 575
            G Y+      A ++   A + V D     PP +I  G       TV       L    +
Sbjct: 423 VGYYICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQG---PVNQTVAVDGTFVLSCVAT 479

Query: 576 GEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHA 635
           G P P  +W +    +     RI+     ++  L I  A+  D+G Y       +GEA  
Sbjct: 480 GSPVPTILWRKDGVLVSTQDSRIKQL---ENGVLQIRYAKLGDTGRYTCIASTPSGEATW 536

Query: 636 SIKVKVVDF---------------PDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYF 680
           S  ++V +F               P  P  P VT+V  +   ++W+P    G +P   Y 
Sbjct: 537 SAYIEVQEFGVPVQPPRPTDPNLIPSAPSKPEVTDVSRNTVTLSWQPNLNSGATP-TSYI 595

Query: 681 IERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRP 736
           IE     S    +   +  K  T   K +     Y   + A NA GIS PS  S P
Sbjct: 596 IEAFSHASGSSWQTVAENVKTETSAIKGLKPNAIYLFLVRAANAYGISDPSQISDP 651



 Score = 80.5 bits (197), Expect = 9e-15
 Identities = 177/766 (23%), Positives = 282/766 (36%), Gaps = 107/766 (13%)

Query: 375  DTTAYCGERVELECEV--SEDDANVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATK 432
            D     GE   +EC+      +  + W K+G    P      RI + G K  L+I    K
Sbjct: 178  DVMVAVGEPAVMECQPPRGHPEPTISWKKDGS---PLDDKDERITIRGGK--LMITYTRK 232

Query: 433  ADAAEYSVMTT---GGQSS--AKLSVDLKPLKILTPLTDQTVNLGKEICLKCEI-SENIP 486
            +DA +Y  + T   G + S  A+L+V  +P  +  P ++  V +      KCE   + +P
Sbjct: 233  SDAGKYVCVGTNMVGERESEVAELTVLERPSFVKRP-SNLAVTVDDSAEFKCEARGDPVP 291

Query: 487  G-KWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAY--NVTLPAKVHV 543
              +W K+   + +S R ++      H L I      D G Y    +         A + V
Sbjct: 292  TVRWRKDDGELPKS-RYEIRDD---HTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTV 347

Query: 544  IDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESY 603
             +PP  ++   D      V  G  +  +   +G P P   W R      EGS  +     
Sbjct: 348  QEPPHFVVKPRDQ----VVALGRTVTFQCEATGNPQPAIFWRR------EGSQNLLFSYQ 397

Query: 604  PDSST----------LVIDIAERDDSGVYHINLKNEAG----EAHASIKVKVVDFPDP-- 647
            P  S+          L I   +R D G Y     N AG    +A+  +   + D P P  
Sbjct: 398  PPQSSSRFSVSQTGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIADRPPPVI 457

Query: 648  ---PVAPTVTEVGDDW--CIMNWEPPA---YDGGSPILGYFIERKKKQSSRWMRLNFDLC 699
               PV  TV   G     C+    P     +     ++     R K+  +  +++ +   
Sbjct: 458  RQGPVNQTVAVDGTFVLSCVATGSPVPTILWRKDGVLVSTQDSRIKQLENGVLQIRYAKL 517

Query: 700  KET------TFEPKKMIEGVAY-EVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVD 752
             +T         P       AY EV+ F V       P  P RP  P  + S P+   V 
Sbjct: 518  GDTGRYTCIASTPSGEATWSAYIEVQEFGV-------PVQPPRPTDPNLIPSAPSKPEVT 570

Query: 753  SVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAK 812
             V+  TVT+ W+P  + GA      +  +       W    +++  +T   I GL  +A 
Sbjct: 571  DVSRNTVTLSWQPNLNSGATPTSYIIEAFSHASGSSWQTVAENVKTETS-AIKGLKPNAI 629

Query: 813  IFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAV-NLVIP-F 870
                V+A NA G S+P   S P+  ++++ P    +     Q   R +G AV +L  P  
Sbjct: 630  YLFLVRAANAYGISDPSQISDPVKTQDVL-PTSQGVDHKQVQ---RELGNAVLHLHNPTV 685

Query: 871  QGKPRPELTWKKD-------GAEIDKNQINIRNSETDTIIF-IRKAERSHSGKYDLQVKV 922
                  E+ W  D       G +I        + E+D ++F +R   ++     DL+  V
Sbjct: 686  LSSSSIEVHWTVDQQSQYIQGYKILYRPSGANHGESDWLVFEVRTPAKNSVVIPDLRKGV 745

Query: 923  DK-------FVETASIDIQI------IDRP-GPPQIVKI--EDVWGENVALTWTPPKDD- 965
            +        F E    D +I       + P  PPQ V +   D  G  + ++W PP +D 
Sbjct: 746  NYEIKARPFFNEFQGADSEIKFAKTLEEAPSAPPQGVTVSKNDGNGTAILVSWQPPPEDT 805

Query: 966  GNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDAT 1025
             N  +  Y +     ++             S  I  LV G  Y   V +    G    + 
Sbjct: 806  QNGMVQEYKVWCLGNETRYHINKTVDGSTFSVVIPFLVPGIRYSVEVAASTGAG----SG 861

Query: 1026 MTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNA 1071
            +  E   I  D   + NPV  +   S A   +  +     IAG  A
Sbjct: 862  VKSEPQFIQLDA--HGNPVSPEDQVSLAQQISDVVKQPAFIAGIGA 905



 Score = 69.7 bits (169), Expect = 2e-11
 Identities = 139/627 (22%), Positives = 235/627 (37%), Gaps = 76/627 (12%)

Query: 445  GQSSAKLSVDLKPLKILTPLTDQTVNLGKEICLKCEISENIPG---KWTKNGLPVQ---- 497
            G + ++L  +  P +I+   +D  V+ G+   L C+ +E  P    +W K G  V+    
Sbjct: 55   GYTGSRLRQEDFPPRIVEHPSDLIVSKGEPATLNCK-AEGRPTPTIEWYKGGERVETDKD 113

Query: 498  --ESDRLKVVHKGRIHKLVIANALTE--DEGDYVFAPDAYNVTLPAKVHVIDPPKIIL-- 551
               S R+ ++  G +  L I +      DEG YV    A N    A  H       IL  
Sbjct: 114  DPRSHRM-LLPSGSLFFLRIVHGRKSRPDEGVYVCV--ARNYLGEAVSHNASLEVAILRD 170

Query: 552  DGLDADNTVTVIAGNKLRLEI-PISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLV 610
            D     + V V  G    +E  P  G P P   W +    + +   RI          L+
Sbjct: 171  DFRQNPSDVMVAVGEPAVMECQPPRGHPEPTISWKKDGSPLDDKDERITIRG----GKLM 226

Query: 611  IDIAERDDSGVYHINLKNEAGEAHASI-KVKVVDFPD-----PPVAPTVTEVGDDWCIMN 664
            I    + D+G Y     N  GE  + + ++ V++ P        +A TV +  +  C   
Sbjct: 227  ITYTRKSDAGKYVCVGTNMVGERESEVAELTVLERPSFVKRPSNLAVTVDDSAEFKCEAR 286

Query: 665  WEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNA 724
             +P               R +K      +  +++  + T + +K+  G        A N 
Sbjct: 287  GDPVP-----------TVRWRKDDGELPKSRYEIRDDHTLKIRKVTAGDMGSYTCVAENM 335

Query: 725  IGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFE 784
            +G ++ S        L V  PP  +      D  V +         A G     + +  E
Sbjct: 336  VGKAEAS------ATLTVQEPPHFVV--KPRDQVVALGRTVTFQCEATGNPQPAIFWRRE 387

Query: 785  GTEDWIVANKDLIDKTKF--------TITGLPTDAKIFVRVKAVNAAGASEPKYYSQPIL 836
            G+++ + + +     ++F        TIT +      +   + +N AG+   K Y +   
Sbjct: 388  GSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTD 447

Query: 837  VKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRN 896
            V     PP IR    + QT    V     L     G P P + W+KDG  +      I+ 
Sbjct: 448  VIADRPPPVIR-QGPVNQTVA--VDGTFVLSCVATGSPVPTILWRKDGVLVSTQDSRIKQ 504

Query: 897  SETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIID--------RPGPPQIV--- 945
             E + ++ IR A+   +G+Y           T S  I++ +        RP  P ++   
Sbjct: 505  LE-NGVLQIRYAKLGDTGRYTCIASTPSGEATWSAYIEVQEFGVPVQPPRPTDPNLIPSA 563

Query: 946  ----KIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKS-MEWFTVIEHYHRTSATIT 1000
                ++ DV    V L+W P  + G A  T Y I+     S   W TV E+    ++ I 
Sbjct: 564  PSKPEVTDVSRNTVTLSWQPNLNSG-ATPTSYIIEAFSHASGSSWQTVAENVKTETSAIK 622

Query: 1001 ELVIGNEYYFRVFSENMCGLSEDATMT 1027
             L     Y F V + N  G+S+ + ++
Sbjct: 623  GLKPNAIYLFLVRAANAYGISDPSQIS 649



 Score = 54.3 bits (129), Expect = 7e-07
 Identities = 78/308 (25%), Positives = 122/308 (39%), Gaps = 69/308 (22%)

Query: 860  VGE-AVNLVIPFQGKPRPELTWKKDGAEID--KNQINIRNSETDTIIFIRKAERSHSGKY 916
            VGE AV    P +G P P ++WKKDG+ +D    +I IR  +    + I    +S +GKY
Sbjct: 183  VGEPAVMECQPPRGHPEPTISWKKDGSPLDDKDERITIRGGK----LMITYTRKSDAGKY 238

Query: 917  DLQVKVDKFVETAS--IDIQIIDRPG----PPQI-VKIED-------VWGENV-ALTWTP 961
             + V  +   E  S   ++ +++RP     P  + V ++D         G+ V  + W  
Sbjct: 239  -VCVGTNMVGERESEVAELTVLERPSFVKRPSNLAVTVDDSAEFKCEARGDPVPTVRWR- 296

Query: 962  PKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLS 1021
             KDDG    + Y I+             +H    +  I ++  G+   +   +ENM G +
Sbjct: 297  -KDDGELPKSRYEIRD------------DH----TLKIRKVTAGDMGSYTCVAENMVGKA 339

Query: 1022 E-DATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGN 1080
            E  AT+T +                      E P F     +     G   T  C   GN
Sbjct: 340  EASATLTVQ----------------------EPPHFVVKPRDQVVALGRTVTFQCEATGN 377

Query: 1081 PKPKITWMK----NKVAIVDDPR-YRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTV 1135
            P+P I W +    N +     P+    FS      L I      D G Y C+ +N  G++
Sbjct: 378  PQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGDLTITNVQRSDVGYYICQTLNVAGSI 437

Query: 1136 EIECKLEV 1143
              +  LEV
Sbjct: 438  ITKAYLEV 445



 Score = 49.7 bits (117), Expect = 2e-05
 Identities = 71/321 (22%), Positives = 122/321 (38%), Gaps = 58/321 (18%)

Query: 843  PPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSE---- 898
            PP  RI  H     + + GE   L    +G+P P + W K G  ++ ++ + R+      
Sbjct: 67   PP--RIVEHPSDLIVSK-GEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLP 123

Query: 899  TDTIIFIR----KAERSHSGKYDLQVKV---DKFVETASIDIQIID---RPGPPQIVKIE 948
            + ++ F+R    +  R   G Y    +    +     AS+++ I+    R  P  ++   
Sbjct: 124  SGSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILRDDFRQNPSDVMVAV 183

Query: 949  DVWGENVALTWTPPKDDGNAAIT----GYTIQKADKK-SMEWFTVIEHYHRTSATITELV 1003
               GE   +   PP+      I+    G  +   D++ ++    ++  Y R S     + 
Sbjct: 184  ---GEPAVMECQPPRGHPEPTISWKKDGSPLDDKDERITIRGGKLMITYTRKSDAGKYVC 240

Query: 1004 IGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNT 1063
            +G          NM G        +ES V              +    E P F +   N 
Sbjct: 241  VGT---------NMVG-------ERESEVA-------------ELTVLERPSFVKRPSNL 271

Query: 1064 YAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGT 1123
                  +A   C  RG+P P + W K+   +    RY +  +    TL+IRK +  D G+
Sbjct: 272  AVTVDDSAEFKCEARGDPVPTVRWRKDDGELPKS-RYEIRDDH---TLKIRKVTAGDMGS 327

Query: 1124 YCCKAVNDLGTVEIECKLEVK 1144
            Y C A N +G  E    L V+
Sbjct: 328  YTCVAENMVGKAEASATLTVQ 348



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 93/383 (24%), Positives = 143/383 (37%), Gaps = 60/383 (15%)

Query: 784  EGTEDWIVANKDLIDKT-KFTITG--------LPTDAKIFVRVKAVNAAGASEPKYYSQP 834
            E T  W      L DK  + TI G          +DA  +V V   N  G  E +     
Sbjct: 199  EPTISWKKDGSPLDDKDERITIRGGKLMITYTRKSDAGKYVCV-GTNMVGERESEVAELT 257

Query: 835  ILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINI 894
            +L +    P  ++ P +L  T    V ++       +G P P + W+KD  E+ K++  I
Sbjct: 258  VLER----PSFVKRPSNLAVT----VDDSAEFKCEARGDPVPTVRWRKDDGELPKSRYEI 309

Query: 895  RNSETDTIIFIRKAERSHSGKYDLQVK--VDKFVETASIDIQIIDRPGPPQ-IVKIEDVW 951
            R+  T   + IRK      G Y    +  V K   +A++ +Q      PP  +VK  D  
Sbjct: 310  RDDHT---LKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQ-----EPPHFVVKPRD-- 359

Query: 952  GENVALTWTPP---KDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSA------TITEL 1002
             + VAL  T     +  GN     +  ++  +  +  +   +   R S       TIT +
Sbjct: 360  -QVVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGDLTITNV 418

Query: 1003 VIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVN 1062
               +  Y+   + N+ G        + + VIA                   P+  Q  VN
Sbjct: 419  QRSDVGYYICQTLNVAGSIITKAYLEVTDVIAD---------------RPPPVIRQGPVN 463

Query: 1063 TYAIAGYNATLNCSVRGNPKPKITWMKNKVAI-VDDPRYRMFSNQGVCTLEIRKPSPYDG 1121
                      L+C   G+P P I W K+ V +   D R +   N GV  L+IR     D 
Sbjct: 464  QTVAVDGTFVLSCVATGSPVPTILWRKDGVLVSTQDSRIKQLEN-GV--LQIRYAKLGDT 520

Query: 1122 GTYCCKAVNDLGTVEIECKLEVK 1144
            G Y C A    G       +EV+
Sbjct: 521  GRYTCIASTPSGEATWSAYIEVQ 543



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 34/88 (38%), Positives = 40/88 (45%), Gaps = 10/88 (11%)

Query: 1068 GYNATLNCSVRGNPKPKITWMKNKVAI---VDDPR-YRMFSNQG----VCTLEIRKPSPY 1119
            G  ATLNC   G P P I W K    +    DDPR +RM    G    +  +  RK  P 
Sbjct: 82   GEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSGSLFFLRIVHGRKSRP- 140

Query: 1120 DGGTYCCKAVNDLG-TVEIECKLEVKVI 1146
            D G Y C A N LG  V     LEV ++
Sbjct: 141  DEGVYVCVARNYLGEAVSHNASLEVAIL 168


>gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens]
          Length = 5065

 Score =  104 bits (260), Expect = 4e-22
 Identities = 204/903 (22%), Positives = 331/903 (36%), Gaps = 139/903 (15%)

Query: 304  PKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEY----YVTAGDEKCSTE 359
            P  +V+W K+ Q + P   ++   +  Q +L I    + D+  Y    +  AG +    +
Sbjct: 1436 PTPQVEWTKDRQPVLPGGPHLQVQEDGQ-VLRITGSHVGDEGRYQCVAFSPAGQQARDFQ 1494

Query: 360  LFVREPP-IMVTKQLEDTTAYCGERVELECEV-SEDDANVKWFKNGEEIIPGPKSRYRIR 417
            L V  PP I  + +  +        V+L CE       N+ WFK+G  +   P S   + 
Sbjct: 1495 LRVHAPPTIWGSNETGEVAVMEDHLVQLLCEARGVPTPNITWFKDGALL---PTSTKVVY 1551

Query: 418  VEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVN------- 470
              G +  L +  A  +DA  Y+   +    +A+ +  L    +  P T +          
Sbjct: 1552 TRGGRQ-LQLGRAQSSDAGVYTCKASNAVGAAEKATRLD---VYVPPTIEGAGGRPYVVK 1607

Query: 471  --LGKEICLKCEISENIPG---KWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGD 525
               G+ + L+C ++   P     W   GLPV ES+  ++   G + +L      +     
Sbjct: 1608 AVAGRPVALEC-VARGHPSPTLSWHHEGLPVAESNESRLETDGSVLRLESPGEASSGLYS 1666

Query: 526  YVFAPDAYNVTLPAKVHVIDPPKIIL-DGLDADNTVTVIAGNKLRLEIPISGEPPPKAMW 584
             V +  A    L   V V  PP++++ +GL     VT I G  L L    SG P P   W
Sbjct: 1667 CVASSPAGEAVLQYSVEVQVPPQLLVAEGL---GQVTTIVGQPLELPCQASGSPVPTIQW 1723

Query: 585  SRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDF 644
             +  +   E +G    +     +TL ID  E D SG++     NEAG A A ++V V   
Sbjct: 1724 LQNGRPAEELAG---VQVASQGTTLHIDHVELDHSGLFACQATNEAGTAGAEVEVSV--- 1777

Query: 645  PDPPVAPTVTEVGDDWCIMNW------------EPPAYDG-GSPILGYFIERKKKQSSRW 691
                 AP V EV       +W            +PP + G G+      +E      S W
Sbjct: 1778 -HGEWAPGVLEVPIGQ--YHWGXEHHSSFPAACDPPVHRGWGAHPKPPLVEGWCSPGSLW 1834

Query: 692  -----MRLNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPP 746
                 + + + L      E   + +   Y     A N  G SK  +  +  VP  +   P
Sbjct: 1835 GEPTGIPVAYSLPPPLQIEKVDLRDEGIYTCA--ATNLAGESKREVALKVLVPPNIEPGP 1892

Query: 747  ---TLLTVDSVTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFT 803
                +L   SVT   +     PPD     G          +    W+     +  +    
Sbjct: 1893 VNKAVLENASVTLECLASGVPPPDVSWFKG---------HQPVSSWMGVTVSVDGRVLRI 1943

Query: 804  ITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEA 863
                 +DA  + R  A N AG++E +Y  +      +  PP+I +P  L    +  V   
Sbjct: 1944 EQAQLSDAGSY-RCVASNVAGSTELRYGLR------VNVPPRITLPPSLPGPVL--VNTP 1994

Query: 864  VNLVIPFQGKPRPELTWKKDGAEID-KNQINIRNSETDTIIFIRKAERSHSGKYDLQVKV 922
            V L     G P P L W KDG  +       ++      ++ +  A  S SG+Y      
Sbjct: 1995 VRLTCNATGAPSPTLMWLKDGNPVSPAGTPGLQVFPGGRVLTLASARASDSGRYSCVAVS 2054

Query: 923  DKFVETASIDIQIIDRPGPPQI----VKIEDVWGENVAL-----TWTPP-----KDDGNA 968
                +   + +Q+     PP I    + +  V  E+VAL        PP     KD    
Sbjct: 2055 AVGEDRQDVVLQV---HMPPSILGEELNVSVVANESVALECQSHAMPPPVLSWWKDGRPL 2111

Query: 969  AITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTK 1028
                     ADK  ++              +    + +  ++   + N  G SE      
Sbjct: 2112 EPRPGVHLSADKALLQ--------------VDRADVWDAGHYTCEALNQAGHSE------ 2151

Query: 1029 ESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIA---GYNATLNCSVRGNPKPKI 1085
                     K Y   V+       AP+F  PL  ++ +    G+  +L+C  RG P PKI
Sbjct: 2152 ---------KHYNLNVW------VAPVF--PLRESHTLTVREGHPTSLSCECRGVPFPKI 2194

Query: 1086 TWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVKV 1145
            +W K+   +  +       +     L + +      GTY C+  N +G    + +LEV V
Sbjct: 2195 SWRKDGQPLPGEGAGLQHVSAVGRLLYLGQAQLAQEGTYTCECSNVVGNSSQDLQLEVHV 2254

Query: 1146 IAQ 1148
              Q
Sbjct: 2255 PPQ 2257



 Score = 94.7 bits (234), Expect = 4e-19
 Identities = 196/889 (22%), Positives = 331/889 (37%), Gaps = 129/889 (14%)

Query: 301  LADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTE- 359
            L +P   + W +NG    PS +      G  ++L ++  ++ D + Y   A ++  S E 
Sbjct: 2870 LGNPVPTISWLQNGLPFSPSPRLQVLEDG--QVLQVSTAEVADAASYMCVAENQAGSAEK 2927

Query: 360  ---LFVREPPIMVTKQLEDTTAYCGERVELECEV-SEDDANVKWFKNGEEIIPGPKSRYR 415
               L V+ PP +    LE  TA     V L C+V +  +  V W+K+ + +  G +    
Sbjct: 2928 LFTLRVQVPPRIAGLDLEQVTAILNSSVSLPCDVHAHPNPEVTWYKDSQALSLGEE---- 2983

Query: 416  IRVEGKKHILIIEGATKADAAEYS--VMTTGG--QSSAKLSVDLKPLKILTPLTDQT--- 468
            + +    H L +  A  +D+  Y+   +   G  Q   +LSV + P     P   Q    
Sbjct: 2984 VFLLPGTHTLQLGRARLSDSGMYTCEALNAAGRDQKLVQLSVLVPPAFRQAPRGPQDAVL 3043

Query: 469  VNLGKEICLKCEISENIPGK---WTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGD 525
            V +G +  L CE ++ +P     W K+G P+  + R + +  G+  +L I  A   D+G 
Sbjct: 3044 VRVGDKAVLSCE-TDALPEPTVTWYKDGQPLVLAQRTQALRGGQ--RLEIQEAQVSDKGL 3100

Query: 526  Y------VFAPDAYNVTLPAKVH-VIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEP 578
            Y      V        TL  +V    + PK          TV+ +AG+ L L   +SG P
Sbjct: 3101 YSCKVSNVAGEAVRTFTLTVQVPPTFENPKT--------ETVSQVAGSPLVLTCDVSGVP 3152

Query: 579  PPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIK 638
             P   W + D+  +E S      S      L +   +   +G Y    +N   EA     
Sbjct: 3153 APTVTWLK-DRMPVESSAVHGVVSR--GGRLQLSRLQPAQAGTYTCVAENTQAEARKDFV 3209

Query: 639  VKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDL 698
            V V+      VAP +   G     +  E    +G    L    + +      W++    L
Sbjct: 3210 VAVL------VAPRIRSSG-----VAREHHVLEGQEVRLDCEADGQPPPDVAWLKDGSPL 3258

Query: 699  CKETTFEPKKMIEGVAYEVRIFAVNAIGI-----SKPSMPSRPFVPLAVTSPPTLL---- 749
             ++     +  ++G +  ++    +  G        P+        + V  PPT+     
Sbjct: 3259 GQDMGPHLRFYLDGGSLVLKGLRASDAGAYTCVAHNPAGEDARLHTVNVLVPPTIKQGAD 3318

Query: 750  ---TVDSVTDTTVTM----RWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKF 802
               T+ S     VTM    R  PP H+     DG  L           ++ + L+  +  
Sbjct: 3319 GSGTLVSRPGELVTMVCPVRGSPPIHVSWLK-DGLPLP----------LSQRTLLHGSGH 3367

Query: 803  TITGLPT---DAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRR 859
            T+        DA IF  V A + AG ++  +  Q       ++ P +  P   +   +  
Sbjct: 3368 TLRISKVQLADAGIFTCV-AASPAGVADRNFTLQ-------VQVPPVLEPVEFQNDVVVV 3419

Query: 860  VGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQ 919
             G  V L    +G P P ++W KDG  +    +     E    + +       SG Y   
Sbjct: 3420 RGSLVELPCEARGVPLPLVSWMKDGEPLLSQSL-----EQGPSLQLEAVGAGDSGTYSCV 3474

Query: 920  VKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKAD 979
               +         + +++ P       IED  G+   L+ TP    G         Q   
Sbjct: 3475 AVSEAGEARRHFQLTVMEPP------HIEDS-GQPTELSLTP----GAPMELLCDAQGTP 3523

Query: 980  KKSMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKI 1039
            + ++ W       H+    +T L   N    RV      GL    T   ES   A + K 
Sbjct: 3524 QPNITW-------HKDGQALTRLE-NNSRATRVLRVRDAGLY---TCLAESPAGAIE-KS 3571

Query: 1040 YKNPVYEDFDF--SEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDD 1097
            ++  V    +      P F         +A     L CSV   P PKITW ++ + + +D
Sbjct: 3572 FRVRVQAPPNIVGPRGPRFV------VGLAPGQLVLECSVEAEPAPKITWHRDGIVLQED 3625

Query: 1098 PRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVKVI 1146
              +  F  +G   L+++  S  D G Y C A N  G+  +  ++E+  +
Sbjct: 3626 -AHTQFPERG-RFLQLQALSTADSGDYSCTARNAAGSTSVAFRVEIHTV 3672



 Score = 90.5 bits (223), Expect = 8e-18
 Identities = 193/910 (21%), Positives = 345/910 (37%), Gaps = 152/910 (16%)

Query: 302  ADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYV----TAGDEKCS 357
            A P   ++WYK+GQ + PS++   +  G  R+L I   Q++D   Y       AG++   
Sbjct: 2665 AVPPPTIRWYKDGQPVTPSSR--LQVLGEGRLLQIQPTQVSDSGRYLCVATNVAGEDDQD 2722

Query: 358  TELFVREPPIM-----------VTKQLEDTTAYCGERVE--------LECEVSE-DDANV 397
              + ++ PP+            +  + E+      E  E        L C+ +     ++
Sbjct: 2723 FNVLIQVPPMFQKVGDFSAAFEILSREEEARGGVTEYREIVENNPAYLYCDTNAIPPPDL 2782

Query: 398  KWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKP 457
             W++  + +  G +    + V     +L I      +A  YS   +       L  +   
Sbjct: 2783 TWYREDQPLSAGDE----VSVLQGGRVLQIPLVRAENAGRYSCKASNEVGEDWLHYE--- 2835

Query: 458  LKILTP----------LTDQTVNLGKEICLKCEISEN-IPG-KWTKNGLPVQESDRLKVV 505
            L +LTP          + + TVN    + L+C    N +P   W +NGLP   S RL+V+
Sbjct: 2836 LLVLTPPVILGDTEELVEEVTVNASSTVSLQCPALGNPVPTISWLQNGLPFSPSPRLQVL 2895

Query: 506  HKGRIHKLVIANALTEDEGDYVFAPD--AYNVTLPAKVHVIDPPKIILDGLDADNTVTVI 563
              G++  L ++ A   D   Y+   +  A +      + V  PP+I   GLD +  VT I
Sbjct: 2896 EDGQV--LQVSTAEVADAASYMCVAENQAGSAEKLFTLRVQVPPRIA--GLDLEQ-VTAI 2950

Query: 564  AGNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYH 623
              + + L   +   P P+  W +  +A+  G         P + TL +  A   DSG+Y 
Sbjct: 2951 LNSSVSLPCDVHAHPNPEVTWYKDSQALSLGE---EVFLLPGTHTLQLGRARLSDSGMYT 3007

Query: 624  INLKNEAGEAHASIKVKVV------DFPDPPVAPTVTEVGDDWCIMNWEPPA-------- 669
                N AG     +++ V+        P  P    +  VGD   +++ E  A        
Sbjct: 3008 CEALNAAGRDQKLVQLSVLVPPAFRQAPRGPQDAVLVRVGDK-AVLSCETDALPEPTVTW 3066

Query: 670  YDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFEPKKM----IEGVAYE-VRIFAVNA 724
            Y  G P++   + ++ +      RL     +E     K +    +  VA E VR F +  
Sbjct: 3067 YKDGQPLV---LAQRTQALRGGQRLEI---QEAQVSDKGLYSCKVSNVAGEAVRTFTLT- 3119

Query: 725  IGISKPSMPSRPFVPLA--VTSPPTLLTVDSVTDTTVTMRW---RPPDHIGAAGLDGYVL 779
              +  P     P       V   P +LT D       T+ W   R P  + ++ + G   
Sbjct: 3120 --VQVPPTFENPKTETVSQVAGSPLVLTCDVSGVPAPTVTWLKDRMP--VESSAVHG--- 3172

Query: 780  EYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKE 839
                      +V+    +  ++      P  A  +  V     A A +         V  
Sbjct: 3173 ----------VVSRGGRLQLSRLQ----PAQAGTYTCVAENTQAEARKD-------FVVA 3211

Query: 840  IIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQ-INIRNSE 898
            ++  P+IR     ++ ++   G+ V L     G+P P++ W KDG+ + ++   ++R   
Sbjct: 3212 VLVAPRIRSSGVAREHHVLE-GQEVRLDCEADGQPPPDVAWLKDGSPLGQDMGPHLRFYL 3270

Query: 899  TDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVA-- 956
                + ++    S +G Y   V  +   E A   +  ++   PP I +  D  G  V+  
Sbjct: 3271 DGGSLVLKGLRASDAGAYTC-VAHNPAGEDAR--LHTVNVLVPPTIKQGADGSGTLVSRP 3327

Query: 957  ---LTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSATITELVIGNEYYFRVF 1013
               +T   P   G+  I    ++      +   T++ H    +  I+++ + +   F   
Sbjct: 3328 GELVTMVCPV-RGSPPIHVSWLKDGLPLPLSQRTLL-HGSGHTLRISKVQLADAGIFTCV 3385

Query: 1014 SENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATL 1073
            + +  G++ D   T +  V          PV E  +F           +   + G    L
Sbjct: 3386 AASPAGVA-DRNFTLQVQV---------PPVLEPVEFQN---------DVVVVRGSLVEL 3426

Query: 1074 NCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLG 1133
             C  RG P P ++WMK+      +P       QG  +L++      D GTY C AV++ G
Sbjct: 3427 PCEARGVPLPLVSWMKD-----GEPLLSQSLEQGP-SLQLEAVGAGDSGTYSCVAVSEAG 3480

Query: 1134 TVEIECKLEV 1143
                  +L V
Sbjct: 3481 EARRHFQLTV 3490



 Score = 80.1 bits (196), Expect = 1e-14
 Identities = 189/910 (20%), Positives = 325/910 (35%), Gaps = 136/910 (14%)

Query: 302  ADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILF-INNCQMTDDSEYYVTAGDEKCSTE- 359
            A P   + W+K+G+ + P       H    + L  ++   + D   Y   A ++   +E 
Sbjct: 2096 AMPPPVLSWWKDGRPLEPRPGV---HLSADKALLQVDRADVWDAGHYTCEALNQAGHSEK 2152

Query: 360  ---LFVREPPIMVTKQLEDTTAYCGERVELECEV-SEDDANVKWFKNGEEIIPGPKSRYR 415
               L V   P+   ++    T   G    L CE        + W K+G+ + PG  +  +
Sbjct: 2153 HYNLNVWVAPVFPLRESHTLTVREGHPTSLSCECRGVPFPKISWRKDGQPL-PGEGAGLQ 2211

Query: 416  IRVEGKKHILIIEGATKADAAEYSVMTTG--GQSSAKLSVDLK-PLKILTPL---TDQTV 469
              V     +L +  A  A    Y+   +   G SS  L +++  P +I  P    T  +V
Sbjct: 2212 -HVSAVGRLLYLGQAQLAQEGTYTCECSNVVGNSSQDLQLEVHVPPQIAGPREPPTQVSV 2270

Query: 470  NLGKEICLKCEISENIPGK--WTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYV 527
                   L+C  +   P    W ++G PV     L++ ++G+   L +  A     G Y 
Sbjct: 2271 VQDGVATLECNATGKPPPTVTWERDGQPVGAELGLQLQNQGQ--SLHVERAQAAHTGRYS 2328

Query: 528  FAPD--AYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWS 585
               +  A       ++ V+ PP++I D LD    +T    + L L     G PPP   W 
Sbjct: 2329 CVAENLAGRAERKFELSVLVPPELIGD-LDPLTNITAALHSPLTLLCEAMGIPPPAIRWF 2387

Query: 586  RGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFP 645
            RG++ +  G     T        L +   +  DSG+Y     NEAGEA  +  V+V+   
Sbjct: 2388 RGEEPVSPGED---TYLLAGGWMLKMTQTQEQDSGLYSCLASNEAGEARRNFSVEVL--- 2441

Query: 646  DPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFE 705
               V P++     +  I        DG +  L   +    +    W +    L +     
Sbjct: 2442 ---VPPSIENEDLEEVI-----KVLDGQTAHLMCNVTGHPQPKLTWFKDGRPLARGDAHH 2493

Query: 706  PKKMIEGVAYEV-----------RIFAVNAIGISKPSMPSRPFVPLAVTSPPTLL-TVDS 753
                 +GV  +V              A NA+G             L+V   PT+L   + 
Sbjct: 2494 ISP--DGVLLQVLQANLSSAGHYSCIAANAVG------EKTKHFQLSVLLAPTILGGAED 2545

Query: 754  VTDTTVTMRWRPPDHIGAAGL-----------DGYVLE-----YCFEGTEDWIVANKDLI 797
              D  VT+    P  +    L           DG   E         GT    + N    
Sbjct: 2546 SADEEVTVTVNNPISLICEALAFPSPNITWMKDGAPFEASRNIQLLPGTHGLQILNAQKE 2605

Query: 798  DKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYI 857
            D  ++T                 N  G +   Y+       E++ PP I     L +  +
Sbjct: 2606 DAGQYTCV-------------VTNELGEAVKNYH------VEVLIPPSISKDDPLGEVGV 2646

Query: 858  RRVGEAVNLVIPFQ----GKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHS 913
            + V   VN  +  +      P P + W KDG  +  +   ++      ++ I+  + S S
Sbjct: 2647 KEVKTKVNSTLTLECESWAVPPPTIRWYKDGQPVTPSS-RLQVLGEGRLLQIQPTQVSDS 2705

Query: 914  GKYDLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGY 973
            G+Y L V  +   E    D  ++ +  PP   K+ D    + A      +++    +T  
Sbjct: 2706 GRY-LCVATNVAGEDDQ-DFNVLIQV-PPMFQKVGDF---SAAFEILSREEEARGGVT-- 2757

Query: 974  TIQKADKKSMEWFTVIEH-----YHRTSATITELVIGNEYYFRVFSENMCGLSEDATMTK 1028
                      E+  ++E+     Y  T+A     +        + + +   + +   + +
Sbjct: 2758 ----------EYREIVENNPAYLYCDTNAIPPPDLTWYREDQPLSAGDEVSVLQGGRVLQ 2807

Query: 1029 ESAVIARDGKIY----KNPVYEDFDFSEAPMFTQPLV---------NTYAIAGYNATLNC 1075
               V A +   Y     N V ED+   E  + T P++              A    +L C
Sbjct: 2808 IPLVRAENAGRYSCKASNEVGEDWLHYELLVLTPPVILGDTEELVEEVTVNASSTVSLQC 2867

Query: 1076 SVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTV 1135
               GNP P I+W++N +     PR ++  +  V  L++      D  +Y C A N  G+ 
Sbjct: 2868 PALGNPVPTISWLQNGLPFSPSPRLQVLEDGQV--LQVSTAEVADAASYMCVAENQAGSA 2925

Query: 1136 EIECKLEVKV 1145
            E    L V+V
Sbjct: 2926 EKLFTLRVQV 2935



 Score = 77.8 bits (190), Expect = 6e-14
 Identities = 180/869 (20%), Positives = 308/869 (35%), Gaps = 107/869 (12%)

Query: 304  PKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTA----GDEKCSTE 359
            P + V W K+G  +  S + +    G    L I+  Q+ D   +   A    G    +  
Sbjct: 3341 PPIHVSWLKDGLPLPLSQRTLLHGSG--HTLRISKVQLADAGIFTCVAASPAGVADRNFT 3398

Query: 360  LFVREPPIMVTKQLE-DTTAYCGERVELECEVSEDDAN-VKWFKNGEEIIP-----GPKS 412
            L V+ PP++   + + D     G  VEL CE        V W K+GE ++      GP  
Sbjct: 3399 LQVQVPPVLEPVEFQNDVVVVRGSLVELPCEARGVPLPLVSWMKDGEPLLSQSLEQGPS- 3457

Query: 413  RYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPL-------- 464
                        L +E     D+  YS +       A+    L    ++ P         
Sbjct: 3458 ------------LQLEAVGAGDSGTYSCVAVSEAGEARRHFQLT---VMEPPHIEDSGQP 3502

Query: 465  TDQTVNLGKEICLKCEISENIPGK---WTKNGLPVQESDRLKVVHKGRIHKLVIANALTE 521
            T+ ++  G  + L C+ ++  P     W K+G   Q   RL+  +  R  +++       
Sbjct: 3503 TELSLTPGAPMELLCD-AQGTPQPNITWHKDG---QALTRLE--NNSRATRVL----RVR 3552

Query: 522  DEGDYVFAPD--AYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPP 579
            D G Y    +  A  +    +V V  PP I+  G      V  +A  +L LE  +  EP 
Sbjct: 3553 DAGLYTCLAESPAGAIEKSFRVRVQAPPNIV--GPRGPRFVVGLAPGQLVLECSVEAEPA 3610

Query: 580  PKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKV 639
            PK  W R    + E +    T+       L +      DSG Y    +N AG    + +V
Sbjct: 3611 PKITWHRDGIVLQEDA---HTQFPERGRFLQLQALSTADSGDYSCTARNAAGSTSVAFRV 3667

Query: 640  KVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDG-GSPILGYFIERKKKQSSRWMRLNFDL 698
            ++   P     P    V  +   +   P   DG  +P++ +   RK +         F++
Sbjct: 3668 EIHTVPTIRSGPPAVNVSVNQTALL--PCQADGVPAPLVSW---RKDRVPLDPRSPRFEI 3722

Query: 699  CKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTT 758
              E +   + ++   A      A N+ G  +     R   P A+   P+ LT+ + T   
Sbjct: 3723 LPEGSLRIQPVLAQDAGHYLCLASNSAGSDRQGRDLRVLEPPAIAPSPSNLTLTAHTPAL 3782

Query: 759  VTMRWR-PPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRV 817
            +       P  +     DG  L++  +     ++ +  L+     T  G P D+  F  V
Sbjct: 3783 LPCEASGSPKPLVVWWKDGQKLDFRLQQGAYRLLPSNALL----LTAPG-PQDSAQFECV 3837

Query: 818  KAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPE 877
             + N  G +  + Y   + V     PP I   +     +   +   V L     G P P 
Sbjct: 3838 VS-NEVGEAH-RLYQVTVHV-----PPTIADDQ---TDFTVTMMAPVVLTCHSTGIPAPT 3887

Query: 878  LTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIID 937
            ++W K GA++       R S +  +  I +A   H+G+Y    +    V    + + +  
Sbjct: 3888 VSWSKAGAQLGARGSGYRVSPSGALE-IGQALPIHAGRYTCSARNSAGVAHKHVFLTVQA 3946

Query: 938  RPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEWFTVIEHYHRTSA 997
             P    +  +     E   L    P +         T QK            E  +  + 
Sbjct: 3947 SPVVKPLPSVVRAVAEEEVLL---PCEASGIPRPTITWQK------------EGLNVATG 3991

Query: 998  TITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFT 1057
              T+++ G +      S    G           + + +   + + P          P+  
Sbjct: 3992 VSTQVLPGGQLRIAHASPEDAGNYLCIAKNSAGSAMGKTRLVVQVP----------PVIE 4041

Query: 1058 QPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPS 1117
              L +     G +A L C  RG+P+P ITW K+   +        F+ Q    L ++   
Sbjct: 4042 NGLPDLSTTEGSHAFLPCKARGSPEPNITWDKDGQPV--SGAEGKFTIQPSGELLVKNLE 4099

Query: 1118 PYDGGTYCCKAVNDLGTVEIECKLEVKVI 1146
              D GTY C A N +G       L + V+
Sbjct: 4100 GQDAGTYTCTAENAVGRARRRVHLTILVL 4128



 Score = 75.5 bits (184), Expect = 3e-13
 Identities = 193/914 (21%), Positives = 339/914 (37%), Gaps = 140/914 (15%)

Query: 273  EKKSAAFAKILDPAY-QVDKGGRVRFVVELAD-----------PKLEVKWYKNGQEIRPS 320
            ++K    + ++ PA+ Q  +G +   +V + D           P+  V WYK+GQ +  +
Sbjct: 3017 DQKLVQLSVLVPPAFRQAPRGPQDAVLVRVGDKAVLSCETDALPEPTVTWYKDGQPLVLA 3076

Query: 321  TKYIFEHKGCQRILFINNCQMTDDSEYYV----TAGDEKCSTELFVREPPIMVTKQLEDT 376
             +     +G QR L I   Q++D   Y       AG+   +  L V+ PP     + E  
Sbjct: 3077 QR-TQALRGGQR-LEIQEAQVSDKGLYSCKVSNVAGEAVRTFTLTVQVPPTFENPKTETV 3134

Query: 377  TAYCGERVELECEVSEDDA-NVKWFKNGEEIIPGPKSRYRIRVEGKKHILIIEGATKADA 435
            +   G  + L C+VS   A  V W K+   +    +S     V  +   L +     A A
Sbjct: 3135 SQVAGSPLVLTCDVSGVPAPTVTWLKDRMPV----ESSAVHGVVSRGGRLQLSRLQPAQA 3190

Query: 436  AEYSVMTTGGQSSAK----LSVDLKP-LKILTPLTDQTVNLGKEICLKCEISENIPGK-- 488
              Y+ +    Q+ A+    ++V + P ++      +  V  G+E+ L CE     P    
Sbjct: 3191 GTYTCVAENTQAEARKDFVVAVLVAPRIRSSGVAREHHVLEGQEVRLDCEADGQPPPDVA 3250

Query: 489  WTKNGLPVQES--DRLKVVHKGRIHKLVIANALTEDEGDYVFAPDAYNVT-LPAKVHVID 545
            W K+G P+ +     L+    G    LV+      D G Y     A+N     A++H ++
Sbjct: 3251 WLKDGSPLGQDMGPHLRFYLDGG--SLVLKGLRASDAGAYTCV--AHNPAGEDARLHTVN 3306

Query: 546  P--PKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSR-------GDKAIMEGSG 596
               P  I  G D   T+    G  + +  P+ G PP    W +         + ++ GSG
Sbjct: 3307 VLVPPTIKQGADGSGTLVSRPGELVTMVCPVRGSPPIHVSWLKDGLPLPLSQRTLLHGSG 3366

Query: 597  RIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVAPTVTEV 656
                       TL I   +  D+G++     + AG A  +  ++V     PPV   V E 
Sbjct: 3367 H----------TLRISKVQLADAGIFTCVAASPAGVADRNFTLQV---QVPPVLEPV-EF 3412

Query: 657  GDDWCIMNW---EPPAYDGGSPILGYFIERKKKQSSRWMRLNFDLCKETTFE-PKKMIEG 712
             +D  ++     E P    G P+              WM+    L  ++  + P   +E 
Sbjct: 3413 QNDVVVVRGSLVELPCEARGVPL----------PLVSWMKDGEPLLSQSLEQGPSLQLEA 3462

Query: 713  VAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDTTVTMRWRPPDHIGAA 772
            V         + + +S+     R F  L V  PP +      T+ ++T          A 
Sbjct: 3463 VG-AGDSGTYSCVAVSEAGEARRHF-QLTVMEPPHIEDSGQPTELSLTPGAPMELLCDAQ 3520

Query: 773  GLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKIFVRVKAVNAAGASEPKYYS 832
            G     + +  +G      A   L + ++ T      DA ++  + A + AGA E  +  
Sbjct: 3521 GTPQPNITWHKDGQ-----ALTRLENNSRATRVLRVRDAGLYTCL-AESPAGAIEKSFRV 3574

Query: 833  QPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQI 892
            +      +  PP I  PR  +       G+ V L    + +P P++TW +DG  + ++  
Sbjct: 3575 R------VQAPPNIVGPRGPRFVVGLAPGQLV-LECSVEAEPAPKITWHRDGIVLQED-A 3626

Query: 893  NIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQI----IDRPGPPQIVKIE 948
            + +  E    + ++    + SG Y    +      + +  ++I      R GPP +    
Sbjct: 3627 HTQFPERGRFLQLQALSTADSGDYSCTARNAAGSTSVAFRVEIHTVPTIRSGPPAV---- 3682

Query: 949  DVWGENVALTWT---PPKDDG-NAAITGYTIQKA--DKKSMEWFTVIEHYHRTSATITEL 1002
                 NV++  T   P + DG  A +  +   +   D +S  +    E     S  I  +
Sbjct: 3683 -----NVSVNQTALLPCQADGVPAPLVSWRKDRVPLDPRSPRF----EILPEGSLRIQPV 3733

Query: 1003 VIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEAPMFTQPLVN 1062
            +  +  ++   + N  G               R G+        D    E P       N
Sbjct: 3734 LAQDAGHYLCLASNSAGSD-------------RQGR--------DLRVLEPPAIAPSPSN 3772

Query: 1063 TYAIAGYNATLNCSVRGNPKPKITWMKNKVAI---VDDPRYRMFSNQGVCTLEIRKPSPY 1119
                A   A L C   G+PKP + W K+   +   +    YR+  +     L +  P P 
Sbjct: 3773 LTLTAHTPALLPCEASGSPKPLVVWWKDGQKLDFRLQQGAYRLLPSN---ALLLTAPGPQ 3829

Query: 1120 DGGTYCCKAVNDLG 1133
            D   + C   N++G
Sbjct: 3830 DSAQFECVVSNEVG 3843



 Score = 74.3 bits (181), Expect = 6e-13
 Identities = 93/371 (25%), Positives = 155/371 (41%), Gaps = 35/371 (9%)

Query: 304  PKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYV-----TAGDEKCST 358
            P+  + W K G  +           G  RI   +     +D+  Y+     +AG     T
Sbjct: 3975 PRPTITWQKEGLNVATGVSTQVLPGGQLRIAHAS----PEDAGNYLCIAKNSAGSAMGKT 4030

Query: 359  ELFVREPPIMVTKQLEDTTAYCGERVELECEV-SEDDANVKWFKNGEEIIPGPKSRYRIR 417
             L V+ PP+ +   L D +   G    L C+     + N+ W K+G+ +  G + ++ I+
Sbjct: 4031 RLVVQVPPV-IENGLPDLSTTEGSHAFLPCKARGSPEPNITWDKDGQPV-SGAEGKFTIQ 4088

Query: 418  VEGKKHILIIEGATKADAAEYSVMTTG--GQSSAKLSVDLKPLKILTPLT-DQTVNLGKE 474
              G+  +  +EG    DA  Y+       G++  ++ + +  L + T L  D+++ LG  
Sbjct: 4089 PSGELLVKNLEGQ---DAGTYTCTAENAVGRARRRVHLTILVLPVFTTLPGDRSLRLGDR 4145

Query: 475  ICLKCEISENIPGK--WTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYV-FAPD 531
            + L+C    +   +  WT N  PV E     V  +     L  A    ED G YV +A +
Sbjct: 4146 LWLRCAARGSPTPRIGWTVNDRPVTEG----VSEQDGGSTLQRAAVSREDSGTYVCWAEN 4201

Query: 532  AYNVTLPAK-VHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKA 590
                T     VHV + P  +L G +A + +    G  ++L+  + G+P P   W + D  
Sbjct: 4202 RVGRTQAVSFVHVKEAP--VLQG-EAFSYLVEPVGGSIQLDCVVRGDPVPDIHWIK-DGL 4257

Query: 591  IMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFPDPPVA 650
             + GS          + +L I   ERDD+G Y    +NE G A   + + +   P   V 
Sbjct: 4258 PLRGS---HLRHQLQNGSLTIHRTERDDAGRYQCLAENEMGVAKKVVILVLQSAPVFQVE 4314

Query: 651  PTVTEV--GDD 659
            P    V  GDD
Sbjct: 4315 PQDMTVRSGDD 4325



 Score = 68.6 bits (166), Expect = 3e-11
 Identities = 89/371 (23%), Positives = 138/371 (37%), Gaps = 35/371 (9%)

Query: 301 LADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTA----GDEKC 356
           L +    + W ++ + +  ST  + +       L I+    TD   Y   A    G  + 
Sbjct: 541 LGEAPYNLTWVRDWRVLPASTGRVAQLADLS--LEISGIIPTDGGRYQCVASNANGVTRA 598

Query: 357 STELFVREPPIMVTKQLEDTTAYCGERVELECEVSE-DDANVKWFKNGEEIIPGPKSRYR 415
           S  L VRE P  V+          G  V++ C  S     ++ W +  + +     SR  
Sbjct: 599 SVWLLVREAP-QVSIHTSSQHFSQGVEVKVSCSASGYPTPHISWSRESQAL--QEDSRIH 655

Query: 416 IRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDL---KPLKILTPLTDQTVNLG 472
           +  +G    LII+G    DA  YS   T    + + +V L    P  +        V +G
Sbjct: 656 VDAQGT---LIIQGVAPEDAGNYSCQATNEVGTDQETVTLYYTDPPSVSAVNAVVLVAVG 712

Query: 473 KEICLKCEISENIPGK--WTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFAP 530
           +E  L CE S   P +  W + GL     + +         KL I  A   D G Y    
Sbjct: 713 EEAVLVCEASGVPPPRVIWYRGGL-----EMILAPEGSSSGKLRIPAAQERDAGTYTCRA 767

Query: 531 --DAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGD 588
             +  + +   ++ V   P++     +    VTV  G    L    +G PPP   W RGD
Sbjct: 768 VNELGDASAEIQLAVGHAPQLT----ELPRDVTVELGRSALLACRATGRPPPTVTWRRGD 823

Query: 589 ---KAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFP 645
                +  G+GR      PDS  L  +    +D   Y    +N  G+  A  ++ V    
Sbjct: 824 GQPLGLRLGAGRGSRSRQPDSGVLFFESVAPEDQAPYVCEARNVFGKVQAEARLIVTGHA 883

Query: 646 DPPV---APTV 653
            P +   APTV
Sbjct: 884 PPQIASSAPTV 894



 Score = 68.2 bits (165), Expect = 4e-11
 Identities = 176/875 (20%), Positives = 326/875 (37%), Gaps = 141/875 (16%)

Query: 304  PKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTELFVR 363
            P+  + W+K+GQ +      +  +    R+L + +  +            EK S  + V+
Sbjct: 3523 PQPNITWHKDGQALTR----LENNSRATRVLRVRDAGLYTCLAESPAGAIEK-SFRVRVQ 3577

Query: 364  EPPIMV-TKQLEDTTAYCGERVELECEVSEDDA-NVKWFKNGEEIIPGPKSRYRIRVEGK 421
             PP +V  +           ++ LEC V  + A  + W ++G  +     +++  R    
Sbjct: 3578 APPNIVGPRGPRFVVGLAPGQLVLECSVEAEPAPKITWHRDGIVLQEDAHTQFPER---- 3633

Query: 422  KHILIIEGATKADAAEYS--VMTTGGQSSAKLSVDLKPLKILT---PLTDQTVNLGKEIC 476
               L ++  + AD+ +YS       G +S    V++  +  +    P  + +VN  +   
Sbjct: 3634 GRFLQLQALSTADSGDYSCTARNAAGSTSVAFRVEIHTVPTIRSGPPAVNVSVN--QTAL 3691

Query: 477  LKCEISENIPG---KWTKNGLPVQ-ESDRLKVVHKGRIHKLVIANALTEDEGDYVF--AP 530
            L C+ ++ +P     W K+ +P+   S R +++ +G +    I   L +D G Y+   + 
Sbjct: 3692 LPCQ-ADGVPAPLVSWRKDRVPLDPRSPRFEILPEGSLR---IQPVLAQDAGHYLCLASN 3747

Query: 531  DAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRG--- 587
             A +      + V++PP I      + + +T+ A     L    SG P P  +W +    
Sbjct: 3748 SAGSDRQGRDLRVLEPPAIA----PSPSNLTLTAHTPALLPCEASGSPKPLVVWWKDGQK 3803

Query: 588  -DKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKV----- 641
             D  + +G+ R+       S+ L++      DS  +   + NE GEAH   +V V     
Sbjct: 3804 LDFRLQQGAYRLLP-----SNALLLTAPGPQDSAQFECVVSNEVGEAHRLYQVTVHVPPT 3858

Query: 642  -----VDFPDPPVAPTVT---EVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMR 693
                  DF    +AP V      G     ++W       G+   GY   R     +  + 
Sbjct: 3859 IADDQTDFTVTMMAPVVLTCHSTGIPAPTVSWSKAGAQLGARGSGY---RVSPSGALEIG 3915

Query: 694  LNFDLCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDS 753
                +         +   GVA++     V A  + KP     P V  AV     LL  ++
Sbjct: 3916 QALPIHAGRYTCSARNSAGVAHKHVFLTVQASPVVKP----LPSVVRAVAEEEVLLPCEA 3971

Query: 754  VTDTTVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITGLPTDAKI 813
                  T+ W+      A G+   VL     G +  I                 P DA  
Sbjct: 3972 SGIPRPTITWQKEGLNVATGVSTQVL----PGGQLRIA-------------HASPEDAGN 4014

Query: 814  FVRVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEAVNLVIPFQGK 873
            ++ + A N+AG++  K        + +++ P + I   L        G    L    +G 
Sbjct: 4015 YLCI-AKNSAGSAMGK-------TRLVVQVPPV-IENGLPDLSTTE-GSHAFLPCKARGS 4064

Query: 874  PRPELTWKKDGAEID--KNQINIRNSETDTIIFIRKAERSHSGKYDLQVK--VDKFVETA 929
            P P +TW KDG  +   + +  I+ S     + ++  E   +G Y    +  V +     
Sbjct: 4065 PEPNITWDKDGQPVSGAEGKFTIQPSGE---LLVKNLEGQDAGTYTCTAENAVGRARRRV 4121

Query: 930  SIDIQII----DRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKKSMEW 985
             + I ++      PG   +   + +W    A     P+        G+T+   D+   E 
Sbjct: 4122 HLTILVLPVFTTLPGDRSLRLGDRLWLRCAARGSPTPR-------IGWTVN--DRPVTEG 4172

Query: 986  FTVIEHYHRTSATITELVIGNE--YYFRVFSENMCGLSEDATM--TKESAVIARDGKIYK 1041
             +  +      +T+    +  E    +  ++EN  G ++  +    KE+ V+        
Sbjct: 4173 VSEQD----GGSTLQRAAVSREDSGTYVCWAENRVGRTQAVSFVHVKEAPVLQG------ 4222

Query: 1042 NPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYR 1101
                E F +   P+            G +  L+C VRG+P P I W+K+ + +       
Sbjct: 4223 ----EAFSYLVEPV------------GGSIQLDCVVRGDPVPDIHWIKDGLPLRGSHLRH 4266

Query: 1102 MFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVE 1136
               N    +L I +    D G Y C A N++G  +
Sbjct: 4267 QLQNG---SLTIHRTERDDAGRYQCLAENEMGVAK 4298



 Score = 63.9 bits (154), Expect = 8e-10
 Identities = 172/826 (20%), Positives = 300/826 (36%), Gaps = 121/826 (14%)

Query: 351  AGDEKCSTELFVREPP-IMVTKQLEDTTAYCGERVELECEVS-EDDANVKWFKNGEEIIP 408
            AG+ +   +L V EPP I  + Q  + +   G  +EL C+       N+ W K+G+ +  
Sbjct: 3479 AGEARRHFQLTVMEPPHIEDSGQPTELSLTPGAPMELLCDAQGTPQPNITWHKDGQALTR 3538

Query: 409  GPKSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLK---PLKILTPLT 465
               +    RV   +           DA  Y+ +      + + S  ++   P  I+ P  
Sbjct: 3539 LENNSRATRVLRVR-----------DAGLYTCLAESPAGAIEKSFRVRVQAPPNIVGPRG 3587

Query: 466  DQ-TVNLGK-EICLKCEISENIPGK--WTKNGLPVQESDRLKVVHKGRIHKLVIANALTE 521
             +  V L   ++ L+C +      K  W ++G+ +QE    +   +GR  +L   +  T 
Sbjct: 3588 PRFVVGLAPGQLVLECSVEAEPAPKITWHRDGIVLQEDAHTQFPERGRFLQLQALS--TA 3645

Query: 522  DEGDYVF----APDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGE 577
            D GDY      A  + +V    ++H +     I  G  A   V V       L     G 
Sbjct: 3646 DSGDYSCTARNAAGSTSVAFRVEIHTVPT---IRSGPPA---VNVSVNQTALLPCQADGV 3699

Query: 578  PPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASI 637
            P P   W R D+  ++     R E  P+ S  +  +  +D +G Y     N AG      
Sbjct: 3700 PAPLVSW-RKDRVPLDPRSP-RFEILPEGSLRIQPVLAQD-AGHYLCLASNSAGSDRQGR 3756

Query: 638  KVKVVDFPDPPVAPTVTEVGDDWCIMNWEPPAYDGGSPILGYFIERKKKQSSRWMRLNFD 697
             ++V++   P +AP+ + +          P    G    L  + +  +K   R  +  + 
Sbjct: 3757 DLRVLE--PPAIAPSPSNLTLTAHTPALLPCEASGSPKPLVVWWKDGQKLDFRLQQGAYR 3814

Query: 698  LCKETTFEPKKMIEGVAYEVRIFAVNAIGISKPSMPSRPFVPLAVTSPPTLLTVDSVTDT 757
            L               + +      N +G       +     + V  PPT+   D  TD 
Sbjct: 3815 LLPSNALLLTAPGPQDSAQFECVVSNEVG------EAHRLYQVTVHVPPTI--ADDQTDF 3866

Query: 758  TVTMRWRPPDHIGAAGLDGYVLEYCFEGTEDWIVANKDLIDKTKFTITG--LPTDAKIFV 815
            TVTM         + G+    + +   G +     +   +  +     G  LP  A  + 
Sbjct: 3867 TVTMMAPVVLTCHSTGIPAPTVSWSKAGAQLGARGSGYRVSPSGALEIGQALPIHAGRYT 3926

Query: 816  RVKAVNAAGASEPKYYSQPILVKEIIEPPKIRIPRHLKQTYIRRVGEA-VNLVIPFQGKP 874
               A N+AG +  K+    +    +++P    +P     + +R V E  V L     G P
Sbjct: 3927 -CSARNSAGVAH-KHVFLTVQASPVVKP----LP-----SVVRAVAEEEVLLPCEASGIP 3975

Query: 875  RPELTWKKDGAEIDKN---------QINIRNSETDT----IIFIRKAERSHSGKYDLQVK 921
            RP +TW+K+G  +            Q+ I ++  +     +   + +  S  GK  L V+
Sbjct: 3976 RPTITWQKEGLNVATGVSTQVLPGGQLRIAHASPEDAGNYLCIAKNSAGSAMGKTRLVVQ 4035

Query: 922  VDKFVETASIDIQIIDRPGPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADKK 981
            V   +E    D+   +  G    +  +        +TW       + A   +TIQ +   
Sbjct: 4036 VPPVIENGLPDLSTTE--GSHAFLPCKARGSPEPNITWDKDGQPVSGAEGKFTIQPSG-- 4091

Query: 982  SMEWFTVIEHYHRTSATITELVIGNEYYFRVFSENMCGLSEDA---TMTKESAVIARDGK 1038
                               EL++          +N+ G  +DA   T T E+AV     +
Sbjct: 4092 -------------------ELLV----------KNLEG--QDAGTYTCTAENAVGRARRR 4120

Query: 1039 IYKNPVYEDFDFSEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDP 1098
            ++   +         P+FT    +     G    L C+ RG+P P+I W  N   + +  
Sbjct: 4121 VHLTILV-------LPVFTTLPGDRSLRLGDRLWLRCAARGSPTPRIGWTVNDRPVTEG- 4172

Query: 1099 RYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVK 1144
               +    G  TL+    S  D GTY C A N +G  +    + VK
Sbjct: 4173 ---VSEQDGGSTLQRAAVSREDSGTYVCWAENRVGRTQAVSFVHVK 4215



 Score = 54.7 bits (130), Expect = 5e-07
 Identities = 32/85 (37%), Positives = 44/85 (51%), Gaps = 11/85 (12%)

Query: 1066 IAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLE-----IRKPSPYD 1120
            +AG NA+L C  RG PKP++TW K   +   +P   +    GV  LE     +   SP D
Sbjct: 1219 VAGENASLPCPARGTPKPQVTWRKGPSS---EP---LHGQPGVAVLEEGSLFLASVSPAD 1272

Query: 1121 GGTYCCKAVNDLGTVEIECKLEVKV 1145
             G Y C+A N++G+     KL V V
Sbjct: 1273 SGDYECQATNEVGSTSRRAKLVVYV 1297



 Score = 50.8 bits (120), Expect = 7e-06
 Identities = 91/381 (23%), Positives = 145/381 (38%), Gaps = 54/381 (14%)

Query: 313  NGQEIRPS------TKYIFEHKGC--QRILFINNCQMTDDSEYYVTAGDEKCSTE----L 360
            + QE+R S      +KY++E  G      L +   Q+ D   Y  TA +   S      L
Sbjct: 1055 SSQEMRLSVNRLALSKYVWEEYGLLPSGSLRLAQVQVGDSGHYECTASNPAGSASHRYVL 1114

Query: 361  FVREPPIMVTKQLEDTTAYCGERVELECEVSED-DANVKWFKNGEEIIP-GPKSRYRIRV 418
             V+ PP  V           GE ++L C    + +  + W K+G  +   GP        
Sbjct: 1115 GVQVPP-QVQPGPRVLKVLVGEALDLNCVAEGNPEPQLSWSKDGVVLQGRGP-------- 1165

Query: 419  EGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQTVNL-----GK 473
            +G  H   I     +DA  Y    +         V+L+ L+      D+T  L     G+
Sbjct: 1166 QGSVHFAAIR---TSDAGRYRCEASNSAGVDAWEVELRVLEPPHWGADETSGLLERVAGE 1222

Query: 474  EICLKCEISENIPGK--WTK--NGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYVFA 529
               L C        +  W K  +  P+     + V+ +G    L +A+    D GDY   
Sbjct: 1223 NASLPCPARGTPKPQVTWRKGPSSEPLHGQPGVAVLEEG---SLFLASVSPADSGDYECQ 1279

Query: 530  P--DAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRG 587
               +  + +  AK+ V  PP I  DG  A+  V+ +AG  L LE   +G P P+ +W + 
Sbjct: 1280 ATNEVGSTSRRAKLVVYVPPSIREDGRKAN--VSGMAGQSLTLECDANGFPVPEIVWLKD 1337

Query: 588  DKAIME-----------GSGRIRTESYPD-SSTLVIDIAERDDSGVYHINLKNEAGEAHA 635
             + +             G G++      D   +L     +  DSG+Y    +N+AG A  
Sbjct: 1338 AQLVGVPLGWAGYGWDLGWGQVGGHRLLDEGQSLHFPRIQEGDSGLYSCRAENQAGTAQR 1397

Query: 636  SIKVKVVDFPDPPVAPTVTEV 656
               + V+  P    A    EV
Sbjct: 1398 DFHLLVLTPPSVLGAGAAQEV 1418



 Score = 50.8 bits (120), Expect = 7e-06
 Identities = 75/346 (21%), Positives = 132/346 (38%), Gaps = 64/346 (18%)

Query: 819  AVNAAGASEPKYYSQPILVKEIIEPPKIRI-PRHLKQTYIRRVGEAVNLVIPFQGKPRPE 877
            A N AG++  +Y      V  +  PP+++  PR LK      VGEA++L    +G P P+
Sbjct: 1101 ASNPAGSASHRY------VLGVQVPPQVQPGPRVLKVL----VGEALDLNCVAEGNPEPQ 1150

Query: 878  LTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKYDLQVKVDKFVETASIDIQIID 937
            L+W KDG       + ++       +       S +G+Y  +      V+   +++++++
Sbjct: 1151 LSWSKDG-------VVLQGRGPQGSVHFAAIRTSDAGRYRCEASNSAGVDAWEVELRVLE 1203

Query: 938  RP---GPPQIVKIEDVWGENVALTWTPPKDDGNAAITGYTIQKADK-KSMEWFTVIEHYH 993
             P          +E V GEN +L   P +      +T      ++         V+E   
Sbjct: 1204 PPHWGADETSGLLERVAGENASLP-CPARGTPKPQVTWRKGPSSEPLHGQPGVAVLEEGS 1262

Query: 994  RTSATITELVIGNEYYFRVFSENMCGLSEDATMTKESAVIARDGKIYKNPVYEDFDFSEA 1053
               A+++    G         +  C  + +   T   A +     +Y  P   + D  +A
Sbjct: 1263 LFLASVSPADSG---------DYECQATNEVGSTSRRAKLV----VYVPPSIRE-DGRKA 1308

Query: 1054 PMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDP--------------- 1098
                    N   +AG + TL C   G P P+I W+K+   +V  P               
Sbjct: 1309 --------NVSGMAGQSLTLECDANGFPVPEIVWLKD-AQLVGVPLGWAGYGWDLGWGQV 1359

Query: 1099 -RYRMFSNQGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1143
              +R+       +L   +    D G Y C+A N  GT + +  L V
Sbjct: 1360 GGHRLLDEGQ--SLHFPRIQEGDSGLYSCRAENQAGTAQRDFHLLV 1403



 Score = 50.4 bits (119), Expect = 9e-06
 Identities = 28/83 (33%), Positives = 43/83 (51%), Gaps = 3/83 (3%)

Query: 1052 EAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTL 1111
            EAP  +    + +   G    ++CS  G P P I+W +   A+ +D R  +   QG  TL
Sbjct: 606  EAPQVSIHTSSQHFSQGVEVKVSCSASGYPTPHISWSRESQALQEDSRIHV-DAQG--TL 662

Query: 1112 EIRKPSPYDGGTYCCKAVNDLGT 1134
             I+  +P D G Y C+A N++GT
Sbjct: 663  IIQGVAPEDAGNYSCQATNEVGT 685



 Score = 50.1 bits (118), Expect = 1e-05
 Identities = 30/80 (37%), Positives = 38/80 (47%), Gaps = 2/80 (2%)

Query: 1068 GYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYCCK 1127
            G  A+L C   G P P ITW K   A+     +   S +G  TL I +PS  D G Y C 
Sbjct: 990  GVPASLPCVASGVPAPTITWTKETNALTSRGPHYNVSKEG--TLLIAQPSAQDAGAYVCT 1047

Query: 1128 AVNDLGTVEIECKLEVKVIA 1147
            A N +G    E +L V  +A
Sbjct: 1048 ATNTVGFSSQEMRLSVNRLA 1067



 Score = 48.9 bits (115), Expect = 3e-05
 Identities = 81/344 (23%), Positives = 133/344 (38%), Gaps = 31/344 (9%)

Query: 304  PKLEVKWYKNGQEIRPST-KYIFEHKGCQRILFINNCQMTDDSEYYVTA----GDEKCST 358
            P+  + W K+GQ +  +  K+  +  G    L + N +  D   Y  TA    G  +   
Sbjct: 4065 PEPNITWDKDGQPVSGAEGKFTIQPSG---ELLVKNLEGQDAGTYTCTAENAVGRARRRV 4121

Query: 359  ELFVREPPIMVTKQLEDTTAYCGERVELECEV-SEDDANVKWFKNGEEIIPGPKSRYRIR 417
             L +   P+  T    D +   G+R+ L C         + W  N   +  G   +    
Sbjct: 4122 HLTILVLPVFTTLP-GDRSLRLGDRLWLRCAARGSPTPRIGWTVNDRPVTEGVSEQDGGS 4180

Query: 418  VEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLKILT--PLTDQTVNLGKEI 475
               +  +   +  T    AE  V    G++ A   V +K   +L     +     +G  I
Sbjct: 4181 TLQRAAVSREDSGTYVCWAENRV----GRTQAVSFVHVKEAPVLQGEAFSYLVEPVGGSI 4236

Query: 476  CLKCEI-SENIPG-KWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDY-VFAPDA 532
             L C +  + +P   W K+GLP++ S     +  G    L I     +D G Y   A + 
Sbjct: 4237 QLDCVVRGDPVPDIHWIKDGLPLRGSHLRHQLQNG---SLTIHRTERDDAGRYQCLAENE 4293

Query: 533  YNVTLPAKVHVIDP-PKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWSRGDKAI 591
              V     + V+   P   ++  D    +TV +G+ + L    +GEP P   W +  +  
Sbjct: 4294 MGVAKKVVILVLQSAPVFQVEPQD----MTVRSGDDVALRCQATGEPTPTIEWLQAGQP- 4348

Query: 592  MEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHA 635
            +  S R+RT   PD S L ++  E  D+G Y     N  G A A
Sbjct: 4349 LRASRRLRT--LPDGS-LWLENVETGDAGTYDCVAHNLLGSATA 4389



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 92/380 (24%), Positives = 141/380 (37%), Gaps = 58/380 (15%)

Query: 302  ADPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYVTAGDEKCSTELF 361
            A+P  ++ W+++G  ++      F  +G  R L +      D  +Y  TA +   ST + 
Sbjct: 3607 AEPAPKITWHRDGIVLQEDAHTQFPERG--RFLQLQALSTADSGDYSCTARNAAGSTSVA 3664

Query: 362  ----------VREPPIMVTKQLEDTTAYCGERVELECEVSEDDAN-VKWFKNGEEIIPGP 410
                      +R  P  V   +  T         L C+     A  V W K+   + P  
Sbjct: 3665 FRVEIHTVPTIRSGPPAVNVSVNQTAL-------LPCQADGVPAPLVSWRKDRVPLDPR- 3716

Query: 411  KSRYRIRVEGKKHILIIEGATKADAAEYSVMTTGGQSSAKLSVDLKPLK---ILTPLTDQ 467
              R+ I  EG    L I+     DA  Y  + +    S +   DL+ L+   I    ++ 
Sbjct: 3717 SPRFEILPEGS---LRIQPVLAQDAGHYLCLASNSAGSDRQGRDLRVLEPPAIAPSPSNL 3773

Query: 468  TVNLGKEICLKCEISENIPGK--WTKNGLPVQ-----------ESDRLKVVHKGRIHKLV 514
            T+       L CE S +      W K+G  +             S+ L +   G      
Sbjct: 3774 TLTAHTPALLPCEASGSPKPLVVWWKDGQKLDFRLQQGAYRLLPSNALLLTAPGPQDSAQ 3833

Query: 515  IANALTEDEGDYVFAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPI 574
                ++ + G+   A   Y VT    VHV  PP I  D    D TVT++A   + L    
Sbjct: 3834 FECVVSNEVGE---AHRLYQVT----VHV--PPTIADD--QTDFTVTMMA--PVVLTCHS 3880

Query: 575  SGEPPPKAMWSR-GDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEA 633
            +G P P   WS+ G +    GSG         S  L I  A    +G Y  + +N AG A
Sbjct: 3881 TGIPAPTVSWSKAGAQLGARGSGY----RVSPSGALEIGQALPIHAGRYTCSARNSAGVA 3936

Query: 634  HASIKVKVVDFPDPPVAPTV 653
            H  + + V   P     P+V
Sbjct: 3937 HKHVFLTVQASPVVKPLPSV 3956



 Score = 44.7 bits (104), Expect = 5e-04
 Identities = 25/78 (32%), Positives = 39/78 (50%), Gaps = 9/78 (11%)

Query: 1068 GYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPY--DGGTYC 1125
            G  A L C   G P P++ W +  + ++  P       +G  + ++R P+    D GTY 
Sbjct: 712  GEEAVLVCEASGVPPPRVIWYRGGLEMILAP-------EGSSSGKLRIPAAQERDAGTYT 764

Query: 1126 CKAVNDLGTVEIECKLEV 1143
            C+AVN+LG    E +L V
Sbjct: 765  CRAVNELGDASAEIQLAV 782



 Score = 39.7 bits (91), Expect = 0.017
 Identities = 49/199 (24%), Positives = 76/199 (38%), Gaps = 34/199 (17%)

Query: 469  VNLGKEICLKCEISENIPG---KWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGD 525
            V +G+ + L C ++E  P     W+K+G+ +Q       VH   I         T D G 
Sbjct: 1131 VLVGEALDLNC-VAEGNPEPQLSWSKDGVVLQGRGPQGSVHFAAIR--------TSDAGR 1181

Query: 526  Y------VFAPDAYNVTLPAKVHVIDPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPP 579
            Y          DA+ V L     V++PP    D  +    +  +AG    L  P  G P 
Sbjct: 1182 YRCEASNSAGVDAWEVEL----RVLEPPHWGAD--ETSGLLERVAGENASLPCPARGTPK 1235

Query: 580  PKAMWSRGDKA-IMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIK 638
            P+  W +G  +  + G   +   +  +  +L +      DSG Y     NE G      K
Sbjct: 1236 PQVTWRKGPSSEPLHGQPGV---AVLEEGSLFLASVSPADSGDYECQATNEVGSTSRRAK 1292

Query: 639  VKVVDFPDPPVAPTVTEVG 657
            + V       V P++ E G
Sbjct: 1293 LVVY------VPPSIREDG 1305



 Score = 39.3 bits (90), Expect = 0.022
 Identities = 78/377 (20%), Positives = 133/377 (35%), Gaps = 63/377 (16%)

Query: 303  DPKLEVKWYKNGQEIRPSTKYIFEHKGCQRILFINNCQMTDDSEYYV----TAGDEKCST 358
            +P+ ++ W K+G         + + +G Q  +     + +D   Y      +AG +    
Sbjct: 1146 NPEPQLSWSKDG--------VVLQGRGPQGSVHFAAIRTSDAGRYRCEASNSAGVDAWEV 1197

Query: 359  ELFVREPPIMVTKQLEDTTA-YCGERVELECEV-SEDDANVKWFKNGEEIIPGPKSRYRI 416
            EL V EPP     +         GE   L C         V W K         +    +
Sbjct: 1198 ELRVLEPPHWGADETSGLLERVAGENASLPCPARGTPKPQVTWRKGPSSEPLHGQPGVAV 1257

Query: 417  RVEGKKHILIIEGATKADAAEYSVMTTGGQSS----AKLSVDLKP-LKILTPLTDQTVNL 471
              EG    L +   + AD+ +Y    T    S    AKL V + P ++      + +   
Sbjct: 1258 LEEGS---LFLASVSPADSGDYECQATNEVGSTSRRAKLVVYVPPSIREDGRKANVSGMA 1314

Query: 472  GKEICLKCEISENIPGKWTKNGLPVQESDRLKVVHK----------------GRI--HKL 513
            G+ + L+C+           NG PV E   LK                    G++  H+L
Sbjct: 1315 GQSLTLECDA----------NGFPVPEIVWLKDAQLVGVPLGWAGYGWDLGWGQVGGHRL 1364

Query: 514  V-------IANALTEDEGDYVFAPDAYNVTLPAKVH--VIDPPKIILDGLDADNTVTVIA 564
            +              D G Y    +    T     H  V+ PP ++  G  A   V  +A
Sbjct: 1365 LDEGQSLHFPRIQEGDSGLYSCRAENQAGTAQRDFHLLVLTPPSVL--GAGAAQEVLGLA 1422

Query: 565  GNKLRLEIPISGEPPPKAMWSRGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHI 624
            G  + L+   SG P P+  W++  + ++ G   ++ +   D   L I  +   D G Y  
Sbjct: 1423 GADVELQCWTSGVPTPQVEWTKDRQPVLPGGPHLQVQE--DGQVLRITGSHVGDEGRYQC 1480

Query: 625  NLKNEAGEAHASIKVKV 641
               + AG+     +++V
Sbjct: 1481 VAFSPAGQQARDFQLRV 1497



 Score = 35.4 bits (80), Expect = 0.31
 Identities = 28/99 (28%), Positives = 40/99 (40%), Gaps = 4/99 (4%)

Query: 1051 SEAPMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKN-KVAIVDDPRYRMFSNQGVC 1109
            ++ P    P  N     G  A L+C V G     +TW+++ +V      R    ++    
Sbjct: 514  TDPPPQLVPAPNVTVSPGETAVLSCRVLGEAPYNLTWVRDWRVLPASTGRVAQLAD---L 570

Query: 1110 TLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEVKVIAQ 1148
            +LEI    P DGG Y C A N  G       L V+   Q
Sbjct: 571  SLEISGIIPTDGGRYQCVASNANGVTRASVWLLVREAPQ 609



 Score = 35.4 bits (80), Expect = 0.31
 Identities = 28/98 (28%), Positives = 40/98 (40%), Gaps = 10/98 (10%)

Query: 1053 APMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKN-------KVAIVDDPRYRMFSN 1105
            AP  T+   +     G +A L C   G P P +TW +        ++      R R   +
Sbjct: 785  APQLTELPRDVTVELGRSALLACRATGRPPPTVTWRRGDGQPLGLRLGAGRGSRSRQ-PD 843

Query: 1106 QGVCTLEIRKPSPYDGGTYCCKAVNDLGTVEIECKLEV 1143
             GV   E    +P D   Y C+A N  G V+ E +L V
Sbjct: 844  SGVLFFE--SVAPEDQAPYVCEARNVFGKVQAEARLIV 879



 Score = 35.0 bits (79), Expect = 0.41
 Identities = 25/92 (27%), Positives = 37/92 (40%), Gaps = 3/92 (3%)

Query: 1053 APMFTQPLVNTYAIAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLE 1112
            AP+F     +    +G +  L C   G P P I W++    +    R R   +    +L 
Sbjct: 4308 APVFQVEPQDMTVRSGDDVALRCQATGEPTPTIEWLQAGQPLRASRRLRTLPDG---SLW 4364

Query: 1113 IRKPSPYDGGTYCCKAVNDLGTVEIECKLEVK 1144
            +      D GTY C A N LG+      L V+
Sbjct: 4365 LENVETGDAGTYDCVAHNLLGSATARAFLVVR 4396



 Score = 34.3 bits (77), Expect = 0.70
 Identities = 53/240 (22%), Positives = 86/240 (35%), Gaps = 29/240 (12%)

Query: 410 PKSRYRIRVEGKKHILIIEG--ATKADAAEYSVMTTGGQSSAKLSVDLKPLKILTPLTDQ 467
           PK R+ ++V+GK H    EG    +     YS +  G            PL  + P    
Sbjct: 394 PKERFYLKVKGKDH----EGNPLLRVSGVSYSGVAPGA-----------PLVSMAPRIHG 438

Query: 468 TVNLGKEICLKCEISENIPGKWTKNGLPVQESDRLKVVHKGRIHKLVIANALTEDEGDYV 527
            ++  + + + C +   +P +        +  +       G      I  A   +EG Y 
Sbjct: 439 YLH--QPLLVSCSVHSALPFRLQLRRGEARLGEERHFQESGN-SSWEILRASKAEEGTYE 495

Query: 528 FAPDAYNVTLPAKVHVI--DPPKIILDGLDADNTVTVIAGNKLRLEIPISGEPPPKAMWS 585
               +   T  AK  ++  DPP  ++   +    VTV  G    L   + GE P    W 
Sbjct: 496 CTAVSRAGTGRAKAQIVVTDPPPQLVPAPN----VTVSPGETAVLSCRVLGEAPYNLTWV 551

Query: 586 RGDKAIMEGSGRIRTESYPDSSTLVIDIAERDDSGVYHINLKNEAGEAHASIKVKVVDFP 645
           R  + +   +GR+      D S  +  I    D G Y     N  G   AS+ + V + P
Sbjct: 552 RDWRVLPASTGRV--AQLADLSLEISGIIP-TDGGRYQCVASNANGVTRASVWLLVREAP 608



 Score = 32.3 bits (72), Expect = 2.7
 Identities = 25/104 (24%), Positives = 52/104 (50%), Gaps = 7/104 (6%)

Query: 857  IRRVGEAVNLVIPFQGKPRPELTWKKDGAEIDKNQINIRNSETDTIIFIRKAERSHSGKY 916
            +  VG ++ L    +G P P++ W KDG  +  +  ++R+   +  + I + ER  +G+Y
Sbjct: 4229 VEPVGGSIQLDCVVRGDPVPDIHWIKDGLPLRGS--HLRHQLQNGSLTIHRTERDDAGRY 4286

Query: 917  DLQVKVDKFVETASIDIQIIDRPGPPQIVKIEDVW---GENVAL 957
              Q   +  +  A   + ++ +  P   V+ +D+    G++VAL
Sbjct: 4287 --QCLAENEMGVAKKVVILVLQSAPVFQVEPQDMTVRSGDDVAL 4328



 Score = 31.6 bits (70), Expect = 4.5
 Identities = 20/78 (25%), Positives = 32/78 (41%), Gaps = 1/78 (1%)

Query: 1066 IAGYNATLNCSVRGNPKPKITWMKNKVAIVDDPRYRMFSNQGVCTLEIRKPSPYDGGTYC 1125
            +AG +  L C   G P P++ W K++  ++    +      G   L I      D G Y 
Sbjct: 1421 LAGADVELQCWTSGVPTPQVEWTKDRQPVLPGGPHLQVQEDGQ-VLRITGSHVGDEGRYQ 1479

Query: 1126 CKAVNDLGTVEIECKLEV 1143
            C A +  G    + +L V
Sbjct: 1480 CVAFSPAGQQARDFQLRV 1497


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.134    0.400 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 49,266,734
Number of Sequences: 37866
Number of extensions: 2484210
Number of successful extensions: 18508
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 180
Number of HSP's successfully gapped in prelim test: 308
Number of HSP's that attempted gapping in prelim test: 9244
Number of HSP's gapped (non-prelim): 4673
length of query: 1148
length of database: 18,247,518
effective HSP length: 113
effective length of query: 1035
effective length of database: 13,968,660
effective search space: 14457563100
effective search space used: 14457563100
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 68 (30.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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