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Search of human proteins with 46048234
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|46048234 nucleolar protein 8 [Homo sapiens]
(1167 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|46048234 nucleolar protein 8 [Homo sapiens] 2332 0.0
gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens] 91 5e-18
gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens] 91 5e-18
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 69 3e-11
gi|217330641 IWS1 homolog [Homo sapiens] 62 4e-09
gi|87299628 biorientation of chromosomes in cell division 1-like... 58 5e-08
gi|6631100 natural killer-tumor recognition sequence [Homo sapiens] 57 8e-08
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] 57 1e-07
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa... 57 1e-07
gi|21264343 scaffold attachment factor B [Homo sapiens] 56 2e-07
gi|31657094 anillin, actin binding protein [Homo sapiens] 54 7e-07
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens] 54 9e-07
gi|33620716 retinoblastoma-binding protein 6 isoform 2 [Homo sap... 54 9e-07
gi|33620769 retinoblastoma-binding protein 6 isoform 1 [Homo sap... 54 9e-07
gi|56676397 ankyrin repeat domain 11 [Homo sapiens] 53 1e-06
gi|7661936 scaffold attachment factor B2 [Homo sapiens] 53 2e-06
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 51 6e-06
gi|42560244 peptidylprolyl isomerase G [Homo sapiens] 51 6e-06
gi|4758172 dentin matrix acidic phosphoprotein 1 isoform 1 precu... 51 7e-06
gi|121256621 dentin matrix acidic phosphoprotein 1 isoform 2 pre... 51 7e-06
gi|16445438 bromodomain and WD repeat domain containing 1 isofor... 51 7e-06
gi|16445436 bromodomain and WD repeat domain containing 1 isofor... 51 7e-06
gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1... 49 3e-05
gi|145580615 KRI1 homolog [Homo sapiens] 48 5e-05
gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo sa... 47 8e-05
gi|62244004 modulator of estrogen induced transcription isoform ... 47 8e-05
gi|63176611 modulator of estrogen induced transcription isoform ... 47 8e-05
gi|41872583 Rho-associated, coiled-coil containing protein kinas... 47 1e-04
gi|8922328 RNA binding motif protein 22 [Homo sapiens] 47 1e-04
gi|24415404 MDN1, midasin homolog [Homo sapiens] 47 1e-04
>gi|46048234 nucleolar protein 8 [Homo sapiens]
Length = 1167
Score = 2332 bits (6043), Expect = 0.0
Identities = 1167/1167 (100%), Positives = 1167/1167 (100%)
Query: 1 MKVNRETKRLYVGGLSQDISEADLQNQFSRFGEVSDVEIITRKDDQGNPQKVFAYINISV 60
MKVNRETKRLYVGGLSQDISEADLQNQFSRFGEVSDVEIITRKDDQGNPQKVFAYINISV
Sbjct: 1 MKVNRETKRLYVGGLSQDISEADLQNQFSRFGEVSDVEIITRKDDQGNPQKVFAYINISV 60
Query: 61 AEADLKKCMSVLNKTKWKGGTLQIQLAKESFLHRLAQEREAAKAKKEESTTGNANLLEKT 120
AEADLKKCMSVLNKTKWKGGTLQIQLAKESFLHRLAQEREAAKAKKEESTTGNANLLEKT
Sbjct: 61 AEADLKKCMSVLNKTKWKGGTLQIQLAKESFLHRLAQEREAAKAKKEESTTGNANLLEKT 120
Query: 121 GGVDFHMKAVPGTEVPGHKNWVVSKFGRVLPVLHLKNQHKRKIIKYDPSKYCHNLKKIGE 180
GGVDFHMKAVPGTEVPGHKNWVVSKFGRVLPVLHLKNQHKRKIIKYDPSKYCHNLKKIGE
Sbjct: 121 GGVDFHMKAVPGTEVPGHKNWVVSKFGRVLPVLHLKNQHKRKIIKYDPSKYCHNLKKIGE 180
Query: 181 DFSNTIPISSLTWELEGGNDPMSKKRRGEFSDFHGPPKKIIKVQKDESSTGSLAMSTRPR 240
DFSNTIPISSLTWELEGGNDPMSKKRRGEFSDFHGPPKKIIKVQKDESSTGSLAMSTRPR
Sbjct: 181 DFSNTIPISSLTWELEGGNDPMSKKRRGEFSDFHGPPKKIIKVQKDESSTGSLAMSTRPR 240
Query: 241 RVIERPPLTQQQAAQKRTCDSITPSKSSPVPVSDTQKLKNLPFKTSGLETAKKRNSISDD 300
RVIERPPLTQQQAAQKRTCDSITPSKSSPVPVSDTQKLKNLPFKTSGLETAKKRNSISDD
Sbjct: 241 RVIERPPLTQQQAAQKRTCDSITPSKSSPVPVSDTQKLKNLPFKTSGLETAKKRNSISDD 300
Query: 301 DTDSEDELRMMIAKEENLQRTTQPSINESESDPFEVVRDDFKSGVHKLHSLIGLGIKNRV 360
DTDSEDELRMMIAKEENLQRTTQPSINESESDPFEVVRDDFKSGVHKLHSLIGLGIKNRV
Sbjct: 301 DTDSEDELRMMIAKEENLQRTTQPSINESESDPFEVVRDDFKSGVHKLHSLIGLGIKNRV 360
Query: 361 SCHDSDDDIMRNDREYDSGDTDEIIAMKKNVAKVKNSTEFSQMEKSTKKTSFKNRENCEL 420
SCHDSDDDIMRNDREYDSGDTDEIIAMKKNVAKVKNSTEFSQMEKSTKKTSFKNRENCEL
Sbjct: 361 SCHDSDDDIMRNDREYDSGDTDEIIAMKKNVAKVKNSTEFSQMEKSTKKTSFKNRENCEL 420
Query: 421 SDHCIKLQKRKSNVESALSHGLKSLNRKSPSHSSSSEDADSASELADSEGGEEYNAMMKN 480
SDHCIKLQKRKSNVESALSHGLKSLNRKSPSHSSSSEDADSASELADSEGGEEYNAMMKN
Sbjct: 421 SDHCIKLQKRKSNVESALSHGLKSLNRKSPSHSSSSEDADSASELADSEGGEEYNAMMKN 480
Query: 481 CLRVNLTLADLEQLAGSDLKVPNEDTKSDGPETTTQCKFDRGSKSPKTPTGLRRGRQCIR 540
CLRVNLTLADLEQLAGSDLKVPNEDTKSDGPETTTQCKFDRGSKSPKTPTGLRRGRQCIR
Sbjct: 481 CLRVNLTLADLEQLAGSDLKVPNEDTKSDGPETTTQCKFDRGSKSPKTPTGLRRGRQCIR 540
Query: 541 PAEIVASLLEGEENTCGKQKPKENNLKPKFQAFKGVGCLYEKESMKKSLKDSVASNNKDQ 600
PAEIVASLLEGEENTCGKQKPKENNLKPKFQAFKGVGCLYEKESMKKSLKDSVASNNKDQ
Sbjct: 541 PAEIVASLLEGEENTCGKQKPKENNLKPKFQAFKGVGCLYEKESMKKSLKDSVASNNKDQ 600
Query: 601 NSMKHEDPSIISMEDGSPYVNGSLGEVTPCQHAKKANGPNYIQPQKRQTTFESQDRKAVS 660
NSMKHEDPSIISMEDGSPYVNGSLGEVTPCQHAKKANGPNYIQPQKRQTTFESQDRKAVS
Sbjct: 601 NSMKHEDPSIISMEDGSPYVNGSLGEVTPCQHAKKANGPNYIQPQKRQTTFESQDRKAVS 660
Query: 661 PSSSEKRSKNPISRPLEGKKSLSLSAKTHNIGFDKDSCHSTTKTEASQEERSDSSGLTSL 720
PSSSEKRSKNPISRPLEGKKSLSLSAKTHNIGFDKDSCHSTTKTEASQEERSDSSGLTSL
Sbjct: 661 PSSSEKRSKNPISRPLEGKKSLSLSAKTHNIGFDKDSCHSTTKTEASQEERSDSSGLTSL 720
Query: 721 KKSPKVSSKDTREIKTDFSLSISNSSDVSAKDKHAEDNEKRLAALEARQKAKEVQKKLVH 780
KKSPKVSSKDTREIKTDFSLSISNSSDVSAKDKHAEDNEKRLAALEARQKAKEVQKKLVH
Sbjct: 721 KKSPKVSSKDTREIKTDFSLSISNSSDVSAKDKHAEDNEKRLAALEARQKAKEVQKKLVH 780
Query: 781 NALANLDGHPEDKPTHIIFGSDSECETEETSTQEQSHPGEEWVKESMGKTSGKLFDSSDD 840
NALANLDGHPEDKPTHIIFGSDSECETEETSTQEQSHPGEEWVKESMGKTSGKLFDSSDD
Sbjct: 781 NALANLDGHPEDKPTHIIFGSDSECETEETSTQEQSHPGEEWVKESMGKTSGKLFDSSDD 840
Query: 841 DESDSEDDSNRFKIKPQFEGRAGQKLMDLQSHFGTDDRFRMDSRFLETDSEEEQEEVNEK 900
DESDSEDDSNRFKIKPQFEGRAGQKLMDLQSHFGTDDRFRMDSRFLETDSEEEQEEVNEK
Sbjct: 841 DESDSEDDSNRFKIKPQFEGRAGQKLMDLQSHFGTDDRFRMDSRFLETDSEEEQEEVNEK 900
Query: 901 KTAEEEELAEEKKKALNVVQSVLQINLSNSTNRGSVAAKKFKDIIHYDPTKQDHATYERK 960
KTAEEEELAEEKKKALNVVQSVLQINLSNSTNRGSVAAKKFKDIIHYDPTKQDHATYERK
Sbjct: 901 KTAEEEELAEEKKKALNVVQSVLQINLSNSTNRGSVAAKKFKDIIHYDPTKQDHATYERK 960
Query: 961 RDDKPKESKAKRKKKREEAEKLPEVSKEMYYNIAMDLKEIFQTTKYTSEKEEGTPWNEDC 1020
RDDKPKESKAKRKKKREEAEKLPEVSKEMYYNIAMDLKEIFQTTKYTSEKEEGTPWNEDC
Sbjct: 961 RDDKPKESKAKRKKKREEAEKLPEVSKEMYYNIAMDLKEIFQTTKYTSEKEEGTPWNEDC 1020
Query: 1021 GKEKPEEIQDPAALTSDAEQPSGFTFSFFDSDTKDIKEETYRVETVKPGKIVWQEDPRLQ 1080
GKEKPEEIQDPAALTSDAEQPSGFTFSFFDSDTKDIKEETYRVETVKPGKIVWQEDPRLQ
Sbjct: 1021 GKEKPEEIQDPAALTSDAEQPSGFTFSFFDSDTKDIKEETYRVETVKPGKIVWQEDPRLQ 1080
Query: 1081 DSSSEEEDVTEETDHRNSSPGEASLLEKETTRFFFFSKNDERLQGSDLFWRGVGSNMSRN 1140
DSSSEEEDVTEETDHRNSSPGEASLLEKETTRFFFFSKNDERLQGSDLFWRGVGSNMSRN
Sbjct: 1081 DSSSEEEDVTEETDHRNSSPGEASLLEKETTRFFFFSKNDERLQGSDLFWRGVGSNMSRN 1140
Query: 1141 SWEARTTNLRMDCRKKHKDAKRKMKPK 1167
SWEARTTNLRMDCRKKHKDAKRKMKPK
Sbjct: 1141 SWEARTTNLRMDCRKKHKDAKRKMKPK 1167
>gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens]
Length = 2454
Score = 91.3 bits (225), Expect = 5e-18
Identities = 202/1011 (19%), Positives = 387/1011 (38%), Gaps = 154/1011 (15%)
Query: 224 QKDESSTGSLAMSTRPRRVIERPPLTQQQAAQKRTCDSITPSK--SSPVPVSDTQKLKNL 281
Q+ ESS+ L +S++ R + T + K +TP +SP+ +D Q++
Sbjct: 516 QEVESSSVKLNISSKDNRGGIKSKTTAK--VTKELYVKLTPVSLSNSPIKGADCQEVPQD 573
Query: 282 P--FKTSGLETAKKRNSISDDDTDSEDELR---MMIAKEENLQRT----TQPSINESESD 332
+K+ GL ++ + +++D+E + ++ +E +L+R+ T P +E++
Sbjct: 574 KDGYKSCGLNPKLEKCGLGQENSDNEHLVENEVSLLLEESDLRRSPRVKTTPLRRPTETN 633
Query: 333 PFEVVRDDFKSGVHKLHSLIGLGIKNRVSCHDSDDDI-----------MRNDREYDSGDT 381
P D+ + K + + ++ + + SD I +++ + D+
Sbjct: 634 PVTSNSDEECNETVKEKQKLSVPVRKKDKRNSSDSAIDNPKPNKLPKSKQSETVDQNSDS 693
Query: 382 DEIIAMKKNVAKVKNS----TEFSQMEKSTKKTSFKNRENCELSDHCIKLQKRKSNVESA 437
DE++A+ K V+++ +S T+ +++ + KT + + D +KRKS+ +
Sbjct: 694 DEMLAILKEVSRMSHSSSSDTDINEIH-TNHKTLYDLKTQAGKDDK--GKRKRKSSTSGS 750
Query: 438 LSHGLKSLNRKSPSHSSSSEDADSASELADSEGGEEYNAMMK------------NCLRVN 485
K + KS S S S DSE +E +M K N +
Sbjct: 751 DFDTKKGKSAKSSIISKKKRQTQSESSNYDSELEKEIKSMSKIGAARTTKKRIPNTKDFD 810
Query: 486 LTLADLEQLAGSD------LKVPNEDTKSDGPETTTQCKFDRGSKSPKTPTGLRRGRQCI 539
+ + G D LK E + D + F + T + R +
Sbjct: 811 SSEDEKHSKKGMDNQGHKNLKTSQEGSSDDAERKQERETFSSAEGTVDKDTTIMELRDRL 870
Query: 540 RPAEIVASLLEGEENTCGKQ--------------KPKENNLKPKF--QAFKGVGCLYEKE 583
+ ++ +G + GK+ K K +LK K + G+ + EK
Sbjct: 871 PKKQQASASTDGVDKLSGKEQSFTSLEVRKVAETKEKSKHLKTKTCKKVQDGLSDIAEK- 929
Query: 584 SMKKSLKDSVASNNKDQNSMKHED---PS-----IISMEDGSPYVNGSLGEVTPCQHAKK 635
+KK D + ++K Q+ E+ PS +I ME Y + S G + +
Sbjct: 930 FLKKDQSDETSEDDKKQSKKGTEEKKKPSDFKKKVIKMEQ--QYESSSDGTEKLPEREEI 987
Query: 636 ANGPNYIQPQKRQTTFESQDRKAVSPSSSEKRSK-NPISRPLEGK-----KSLSLSAKTH 689
+ P I+ K TT + K + +S+K+ + + + GK S +K
Sbjct: 988 CHFPKGIKQIKNGTTDGEKKSKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSEDKKSKNG 1047
Query: 690 NIGFDKDSCHSTTKTEASQEERSDSSGLTSLKKSPKVSSKDTR----EIKTDFSLS---- 741
G +K C K+ +++ S S K +S D R E++ +LS
Sbjct: 1048 AYGREKKRCKLLGKSSRKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNLSSKRN 1107
Query: 742 ---ISNSSDVSAKDKHAEDNEKRLAALEARQKAKEVQKKLVHNALANLDGHPEDKPTHII 798
I + S S ++ +EDN+K+ +++KA V++K ++ L + K I
Sbjct: 1108 TKEIQSGSSSSDAEESSEDNKKKKQRTSSKKKAVIVKEKKRNS----LRTSTKRKQADIT 1163
Query: 799 FGSDSECETEETSTQEQSHPGEEWVK---ESMGKTSGKLFDSSD-------------DDE 842
S S+ E ++ ++ + E+ +K E++ +S F S DD+
Sbjct: 1164 SSSSSDIEDDDQNSIGEGSSDEQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDDD 1223
Query: 843 SDSEDDSNRF-------KIKPQF----------EGRAGQKLMDLQSHFGTDDRFRMDSRF 885
D D NR +IK E G+K Q+ D +
Sbjct: 1224 DDDNDPENRIAKKMLLEEIKANLSSDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVN 1283
Query: 886 LETDSEEEQEE--------VNEKKTAEEEELAEEKKKALNVVQSVLQINLSNSTNRGSVA 937
E+DS+ E+ + + K T + E EEKK + V NR V+
Sbjct: 1284 SESDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEV------KGRNRRKVS 1337
Query: 938 AKKFKDIIHYDPTKQDHATYERKRDDKPKESKAKRKKKREEAEKLPEVSKEMYYNIAMDL 997
++ +D + + + E + + +P+ AK+ + E + K + D
Sbjct: 1338 SEDSEDSDFQESGVSEEVS-ESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDS 1396
Query: 998 KEIFQTTKYTSEKEEGTPWNEDCGKEKPEEIQDPAALTSDAEQPSGFTFSFFDSDTKDIK 1057
K SE+EE E+ +E+ EE ++ D++ P K +K
Sbjct: 1397 S---SENKSNSEEEEEEKEEEE--EEEEEEEEEEEDENDDSKSPGKGRKKI----RKILK 1447
Query: 1058 EETYRVETVKPGKIVWQEDPRLQDSSSEEEDVTEETDHRNSSPGEASLLEK 1108
++ R ET K + R+ + E E + E + ++SP + + K
Sbjct: 1448 DDKLRTETQNALKEEEERRKRIAEREREREKLREVIEIEDASPTKCPITTK 1498
Score = 60.8 bits (146), Expect = 7e-09
Identities = 159/810 (19%), Positives = 293/810 (36%), Gaps = 119/810 (14%)
Query: 399 EFSQMEKSTKKTSFKNRENCELSDHCIKLQKRKSNVESALSHGLKSLNRKSPSH--SSSS 456
E + KS K S K ++ + + + +++++N + H KS ++ P + +++S
Sbjct: 415 EKKDISKSEAKLSRKQVDSEHMHQN-VPTEEQRTNKSTGGEHK-KSDRKEEPQYEPANTS 472
Query: 457 EDADSASELADSEGGEEYNAMMKNCLRVNLTLADLEQLAGSDLKVPNEDTKSDGPETTTQ 516
ED D S E+ ++ + V ++ G ++ +S +
Sbjct: 473 EDLDMDIVSVPSSVPEDIFENLETAMEVQSSVDH----QGDGSSGTEQEVESSSVKLNIS 528
Query: 517 CKFDRGSKSPKTPTGLRRGRQC-IRPAEIVASLLEG---EENTCGKQKPKENNLKPKFQA 572
K +RG KT + + + P + S ++G +E K K L PK +
Sbjct: 529 SKDNRGGIKSKTTAKVTKELYVKLTPVSLSNSPIKGADCQEVPQDKDGYKSCGLNPKLE- 587
Query: 573 FKGVGCLYEKESMKKSLKDSVASNNKDQNSMKHEDPSIISMEDG---SPYVNGSLGEVTP 629
K + N D + + S++ E SP V + TP
Sbjct: 588 -----------------KCGLGQENSDNEHLVENEVSLLLEESDLRRSPRV-----KTTP 625
Query: 630 CQHAKKANGPNYIQPQKRQTTFESQDRKAVSPSSSEKR--SKNPISRPLEGKKSLSLSAK 687
+ + N ++ T + + + +V +KR S + I P K S ++
Sbjct: 626 LRRPTETNPVTSNSDEECNETVKEKQKLSVPVRKKDKRNSSDSAIDNPKPNKLPKSKQSE 685
Query: 688 THNIGFDKDSC-----------HSTTKTEASQEERSDSSGLTSLKKSPKVSSKDTREIKT 736
T + D D HS++ E ++ L LK K R+ K+
Sbjct: 686 TVDQNSDSDEMLAILKEVSRMSHSSSSDTDINEIHTNHKTLYDLKTQAGKDDKGKRKRKS 745
Query: 737 DFSLSISNSSDVSAKDKHAEDNEKRLAALEARQKAKEVQKKLVHNALANLDGHPEDKPTH 796
S S ++ + +KR E+ E++K++ +++ + K
Sbjct: 746 STSGSDFDTKKGKSAKSSIISKKKRQTQSESSNYDSELEKEI--KSMSKIGAARTTKKRI 803
Query: 797 IIFGSDSECETEETSTQEQSHPGEEWVKESMGKTSGKLFDSSDDDESDSEDDSNRFKIKP 856
E E+ S + + G + +K S + S DD+ R + +
Sbjct: 804 PNTKDFDSSEDEKHSKKGMDNQGHKNLKTS---------------QEGSSDDAERKQERE 848
Query: 857 QFEGRAGQ-----KLMDLQSHFGTDDRFRMDSRFLETDSEEEQE--EVNEKKTAEEEELA 909
F G +M+L+ + + ++ S +EQ + +K AE +E +
Sbjct: 849 TFSSAEGTVDKDTTIMELRDRLPKKQQASASTDGVDKLSGKEQSFTSLEVRKVAETKEKS 908
Query: 910 EE-KKKALNVVQSVLQINLSNSTNRGSVAAKKFKDIIHYDPTKQDHATYERKRDDKPKES 968
+ K K VQ L S A+KF K+D + E DDK +
Sbjct: 909 KHLKTKTCKKVQDGL-----------SDIAEKF--------LKKDQSD-ETSEDDKKQSK 948
Query: 969 KAKRKKKREEAEKLPEVSKEMYYNIAMD-------LKEIFQTTKYTSEKEEGTPWNEDCG 1021
K +KK+ K + E Y + D +EI K + + GT G
Sbjct: 949 KGTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLPEREEICHFPKGIKQIKNGTT----DG 1004
Query: 1022 KEKPEEIQDPAALTSD-----AEQPSGFTFSFFDSDTKDIKEETYRVETVKPGKIVWQED 1076
++K ++I+D + D AE+ +G S S+ K K Y E K K++ +
Sbjct: 1005 EKKSKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSEDKKSKNGAYGREK-KRCKLLGKSS 1063
Query: 1077 PRLQD-SSSEEEDVTEETDHRNSSPGEASLLEKETTRFFFFSKNDERLQGSDLFWRGVGS 1135
+ QD SSS+ E + + D NSS +E R +N + +Q S
Sbjct: 1064 RKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNLSSKRNTKEIQSG-----SSSS 1118
Query: 1136 NMSRNSWEARTTNLRMDCRKKHKDAKRKMK 1165
+ +S + + R +KK K K +
Sbjct: 1119 DAEESSEDNKKKKQRTSSKKKAVIVKEKKR 1148
>gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens]
Length = 2492
Score = 91.3 bits (225), Expect = 5e-18
Identities = 202/1011 (19%), Positives = 387/1011 (38%), Gaps = 154/1011 (15%)
Query: 224 QKDESSTGSLAMSTRPRRVIERPPLTQQQAAQKRTCDSITPSK--SSPVPVSDTQKLKNL 281
Q+ ESS+ L +S++ R + T + K +TP +SP+ +D Q++
Sbjct: 554 QEVESSSVKLNISSKDNRGGIKSKTTAK--VTKELYVKLTPVSLSNSPIKGADCQEVPQD 611
Query: 282 P--FKTSGLETAKKRNSISDDDTDSEDELR---MMIAKEENLQRT----TQPSINESESD 332
+K+ GL ++ + +++D+E + ++ +E +L+R+ T P +E++
Sbjct: 612 KDGYKSCGLNPKLEKCGLGQENSDNEHLVENEVSLLLEESDLRRSPRVKTTPLRRPTETN 671
Query: 333 PFEVVRDDFKSGVHKLHSLIGLGIKNRVSCHDSDDDI-----------MRNDREYDSGDT 381
P D+ + K + + ++ + + SD I +++ + D+
Sbjct: 672 PVTSNSDEECNETVKEKQKLSVPVRKKDKRNSSDSAIDNPKPNKLPKSKQSETVDQNSDS 731
Query: 382 DEIIAMKKNVAKVKNS----TEFSQMEKSTKKTSFKNRENCELSDHCIKLQKRKSNVESA 437
DE++A+ K V+++ +S T+ +++ + KT + + D +KRKS+ +
Sbjct: 732 DEMLAILKEVSRMSHSSSSDTDINEIH-TNHKTLYDLKTQAGKDDK--GKRKRKSSTSGS 788
Query: 438 LSHGLKSLNRKSPSHSSSSEDADSASELADSEGGEEYNAMMK------------NCLRVN 485
K + KS S S S DSE +E +M K N +
Sbjct: 789 DFDTKKGKSAKSSIISKKKRQTQSESSNYDSELEKEIKSMSKIGAARTTKKRIPNTKDFD 848
Query: 486 LTLADLEQLAGSD------LKVPNEDTKSDGPETTTQCKFDRGSKSPKTPTGLRRGRQCI 539
+ + G D LK E + D + F + T + R +
Sbjct: 849 SSEDEKHSKKGMDNQGHKNLKTSQEGSSDDAERKQERETFSSAEGTVDKDTTIMELRDRL 908
Query: 540 RPAEIVASLLEGEENTCGKQ--------------KPKENNLKPKF--QAFKGVGCLYEKE 583
+ ++ +G + GK+ K K +LK K + G+ + EK
Sbjct: 909 PKKQQASASTDGVDKLSGKEQSFTSLEVRKVAETKEKSKHLKTKTCKKVQDGLSDIAEK- 967
Query: 584 SMKKSLKDSVASNNKDQNSMKHED---PS-----IISMEDGSPYVNGSLGEVTPCQHAKK 635
+KK D + ++K Q+ E+ PS +I ME Y + S G + +
Sbjct: 968 FLKKDQSDETSEDDKKQSKKGTEEKKKPSDFKKKVIKMEQ--QYESSSDGTEKLPEREEI 1025
Query: 636 ANGPNYIQPQKRQTTFESQDRKAVSPSSSEKRSK-NPISRPLEGK-----KSLSLSAKTH 689
+ P I+ K TT + K + +S+K+ + + + GK S +K
Sbjct: 1026 CHFPKGIKQIKNGTTDGEKKSKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSEDKKSKNG 1085
Query: 690 NIGFDKDSCHSTTKTEASQEERSDSSGLTSLKKSPKVSSKDTR----EIKTDFSLS---- 741
G +K C K+ +++ S S K +S D R E++ +LS
Sbjct: 1086 AYGREKKRCKLLGKSSRKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNLSSKRN 1145
Query: 742 ---ISNSSDVSAKDKHAEDNEKRLAALEARQKAKEVQKKLVHNALANLDGHPEDKPTHII 798
I + S S ++ +EDN+K+ +++KA V++K ++ L + K I
Sbjct: 1146 TKEIQSGSSSSDAEESSEDNKKKKQRTSSKKKAVIVKEKKRNS----LRTSTKRKQADIT 1201
Query: 799 FGSDSECETEETSTQEQSHPGEEWVK---ESMGKTSGKLFDSSD-------------DDE 842
S S+ E ++ ++ + E+ +K E++ +S F S DD+
Sbjct: 1202 SSSSSDIEDDDQNSIGEGSSDEQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDDD 1261
Query: 843 SDSEDDSNRF-------KIKPQF----------EGRAGQKLMDLQSHFGTDDRFRMDSRF 885
D D NR +IK E G+K Q+ D +
Sbjct: 1262 DDDNDPENRIAKKMLLEEIKANLSSDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVN 1321
Query: 886 LETDSEEEQEE--------VNEKKTAEEEELAEEKKKALNVVQSVLQINLSNSTNRGSVA 937
E+DS+ E+ + + K T + E EEKK + V NR V+
Sbjct: 1322 SESDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEV------KGRNRRKVS 1375
Query: 938 AKKFKDIIHYDPTKQDHATYERKRDDKPKESKAKRKKKREEAEKLPEVSKEMYYNIAMDL 997
++ +D + + + E + + +P+ AK+ + E + K + D
Sbjct: 1376 SEDSEDSDFQESGVSEEVS-ESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDS 1434
Query: 998 KEIFQTTKYTSEKEEGTPWNEDCGKEKPEEIQDPAALTSDAEQPSGFTFSFFDSDTKDIK 1057
K SE+EE E+ +E+ EE ++ D++ P K +K
Sbjct: 1435 S---SENKSNSEEEEEEKEEEE--EEEEEEEEEEEDENDDSKSPGKGRKKI----RKILK 1485
Query: 1058 EETYRVETVKPGKIVWQEDPRLQDSSSEEEDVTEETDHRNSSPGEASLLEK 1108
++ R ET K + R+ + E E + E + ++SP + + K
Sbjct: 1486 DDKLRTETQNALKEEEERRKRIAEREREREKLREVIEIEDASPTKCPITTK 1536
Score = 60.8 bits (146), Expect = 7e-09
Identities = 159/810 (19%), Positives = 293/810 (36%), Gaps = 119/810 (14%)
Query: 399 EFSQMEKSTKKTSFKNRENCELSDHCIKLQKRKSNVESALSHGLKSLNRKSPSH--SSSS 456
E + KS K S K ++ + + + +++++N + H KS ++ P + +++S
Sbjct: 453 EKKDISKSEAKLSRKQVDSEHMHQN-VPTEEQRTNKSTGGEHK-KSDRKEEPQYEPANTS 510
Query: 457 EDADSASELADSEGGEEYNAMMKNCLRVNLTLADLEQLAGSDLKVPNEDTKSDGPETTTQ 516
ED D S E+ ++ + V ++ G ++ +S +
Sbjct: 511 EDLDMDIVSVPSSVPEDIFENLETAMEVQSSVDH----QGDGSSGTEQEVESSSVKLNIS 566
Query: 517 CKFDRGSKSPKTPTGLRRGRQC-IRPAEIVASLLEG---EENTCGKQKPKENNLKPKFQA 572
K +RG KT + + + P + S ++G +E K K L PK +
Sbjct: 567 SKDNRGGIKSKTTAKVTKELYVKLTPVSLSNSPIKGADCQEVPQDKDGYKSCGLNPKLE- 625
Query: 573 FKGVGCLYEKESMKKSLKDSVASNNKDQNSMKHEDPSIISMEDG---SPYVNGSLGEVTP 629
K + N D + + S++ E SP V + TP
Sbjct: 626 -----------------KCGLGQENSDNEHLVENEVSLLLEESDLRRSPRV-----KTTP 663
Query: 630 CQHAKKANGPNYIQPQKRQTTFESQDRKAVSPSSSEKR--SKNPISRPLEGKKSLSLSAK 687
+ + N ++ T + + + +V +KR S + I P K S ++
Sbjct: 664 LRRPTETNPVTSNSDEECNETVKEKQKLSVPVRKKDKRNSSDSAIDNPKPNKLPKSKQSE 723
Query: 688 THNIGFDKDSC-----------HSTTKTEASQEERSDSSGLTSLKKSPKVSSKDTREIKT 736
T + D D HS++ E ++ L LK K R+ K+
Sbjct: 724 TVDQNSDSDEMLAILKEVSRMSHSSSSDTDINEIHTNHKTLYDLKTQAGKDDKGKRKRKS 783
Query: 737 DFSLSISNSSDVSAKDKHAEDNEKRLAALEARQKAKEVQKKLVHNALANLDGHPEDKPTH 796
S S ++ + +KR E+ E++K++ +++ + K
Sbjct: 784 STSGSDFDTKKGKSAKSSIISKKKRQTQSESSNYDSELEKEI--KSMSKIGAARTTKKRI 841
Query: 797 IIFGSDSECETEETSTQEQSHPGEEWVKESMGKTSGKLFDSSDDDESDSEDDSNRFKIKP 856
E E+ S + + G + +K S + S DD+ R + +
Sbjct: 842 PNTKDFDSSEDEKHSKKGMDNQGHKNLKTS---------------QEGSSDDAERKQERE 886
Query: 857 QFEGRAGQ-----KLMDLQSHFGTDDRFRMDSRFLETDSEEEQE--EVNEKKTAEEEELA 909
F G +M+L+ + + ++ S +EQ + +K AE +E +
Sbjct: 887 TFSSAEGTVDKDTTIMELRDRLPKKQQASASTDGVDKLSGKEQSFTSLEVRKVAETKEKS 946
Query: 910 EE-KKKALNVVQSVLQINLSNSTNRGSVAAKKFKDIIHYDPTKQDHATYERKRDDKPKES 968
+ K K VQ L S A+KF K+D + E DDK +
Sbjct: 947 KHLKTKTCKKVQDGL-----------SDIAEKF--------LKKDQSD-ETSEDDKKQSK 986
Query: 969 KAKRKKKREEAEKLPEVSKEMYYNIAMD-------LKEIFQTTKYTSEKEEGTPWNEDCG 1021
K +KK+ K + E Y + D +EI K + + GT G
Sbjct: 987 KGTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLPEREEICHFPKGIKQIKNGTT----DG 1042
Query: 1022 KEKPEEIQDPAALTSD-----AEQPSGFTFSFFDSDTKDIKEETYRVETVKPGKIVWQED 1076
++K ++I+D + D AE+ +G S S+ K K Y E K K++ +
Sbjct: 1043 EKKSKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSEDKKSKNGAYGREK-KRCKLLGKSS 1101
Query: 1077 PRLQD-SSSEEEDVTEETDHRNSSPGEASLLEKETTRFFFFSKNDERLQGSDLFWRGVGS 1135
+ QD SSS+ E + + D NSS +E R +N + +Q S
Sbjct: 1102 RKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNLSSKRNTKEIQSG-----SSSS 1156
Query: 1136 NMSRNSWEARTTNLRMDCRKKHKDAKRKMK 1165
+ +S + + R +KK K K +
Sbjct: 1157 DAEESSEDNKKKKQRTSSKKKAVIVKEKKR 1186
>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
Length = 1301
Score = 68.9 bits (167), Expect = 3e-11
Identities = 112/596 (18%), Positives = 207/596 (34%), Gaps = 48/596 (8%)
Query: 260 DSITPSKSSPVPVSDTQKLKNLPFKTSGLETAKKRNSISDDDTDSEDELRMMIAKEENLQ 319
DS + SS SD+ + +S + +S S D +DS D +K ++ +
Sbjct: 570 DSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSD-SSDSSDSSDSSDSSDSSDSKSDSSK 628
Query: 320 RTTQPSINESESDPFEVVRDDFKSGVHKLHSLIGLGIKNRVSCHDSDDDIMRNDREYDSG 379
+ S ++S+SD + D S + DS D +D S
Sbjct: 629 SESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSSD 688
Query: 380 DTDEIIAMKKNVAKVKNSTEFSQMEKS----TKKTSFKNRENCELSDHCIKLQKRKSNVE 435
+D + N ++ +S++ S + S + ++ + ++ SD S+
Sbjct: 689 SSDS--SDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDS 746
Query: 436 SALSHGLKSLNRKSPSHSSSSEDADSASELADSEGGEEYNAMMKNCLRVNLTLADLEQLA 495
S S+ S + S+SS S D+ +S+ +DS + N + +D +
Sbjct: 747 SDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNS--------SDSSDSS 798
Query: 496 GSDLKVPNEDTKSDGPETTTQCKFDRGSKSPKTPTGLRRGRQCIRPAEIVASLLEGEENT 555
S + SD +++ D + S + + + + +G ++
Sbjct: 799 NSS----DSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSD 854
Query: 556 CGKQKPKENNLKPKFQAFKGVGCLYEKESMKKSLKDSVASNNKDQNSMKHEDPSIISMED 615
+ N+ + +S S + +N+ NS D S S D
Sbjct: 855 SSNRSDSSNSSDSSDSS----------DSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSD 904
Query: 616 GSPYVNGSLGEVTPCQHAKKANGPNYIQPQKRQTTFESQDRKAVSPSSSEKRSKNPISRP 675
S N S + +N + + S D S SS S N
Sbjct: 905 SSDSSNSS-------DSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSS 957
Query: 676 LEGKKSLSLSAKTHNIGFDKDSCHSTTKTEASQEERSDSSGLTSLKKSPKVSSKDTREIK 735
S S + N DS +S+ +++S + SDSS S +S D+ +
Sbjct: 958 NSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSS--DSSDSS-----DSSDSSNSSDSSDSS 1010
Query: 736 TDFSLSISNSSDVSAKDKHAEDNEKRLAALEARQKAKEVQKKLVHNALANLDGHPEDKPT 795
S S+ S S+ ++ D+ + ++ + N+ + D +
Sbjct: 1011 DSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSS 1070
Query: 796 HIIFGSDSECETEETSTQEQSHPGEEWVKESMGKTSGKLFDSSD-DDESDSEDDSN 850
SDS +E + + + S+ + S S DSSD D SDS D SN
Sbjct: 1071 DSSDSSDSSDSSESSDSSDSSNSSD----SSDSSDSSDSSDSSDSSDSSDSSDSSN 1122
Score = 62.0 bits (149), Expect = 3e-09
Identities = 143/869 (16%), Positives = 291/869 (33%), Gaps = 61/869 (7%)
Query: 296 SISDDDTDSEDELRMMIAKEENLQRTTQPSINESESDPFEVVRDDFKSGVHKLHSLIGLG 355
S+ DD +S DE N ++ N S D+ K G G
Sbjct: 459 SMQGDDPNSSDE------SNGNDDANSESDNNSSSRGDASYNSDESKDN--------GNG 504
Query: 356 IKNRVSCHDSDDDIMRNDREYDS---GDTDEIIAMKKNVAKVKNSTEFSQMEKSTKKTSF 412
++ D D D + DS G+ K + K K+ + S S+ +
Sbjct: 505 SDSK-GAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSDSDSSDSSNSSDS 563
Query: 413 KNRENCELSDHCIKLQKRKSNVESALSHGLKSLNRKSPSHSSSSEDADSASELADSEGGE 472
+ + + SD S+ +S+ S S + + S SS S D+ +S+ +DS +
Sbjct: 564 SDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSK 623
Query: 473 EYNAMMKNCLRVNLTLADLEQLAGSDLKVPNEDTKSDGPETTTQCKFDRGSKSPKTPTGL 532
++ ++ + + +D SD N D+ + + D S + +
Sbjct: 624 SDSSKSESDSSDSDSKSDSSDSNSSDSS-DNSDSSDSSNSSNSSDSSDSSDSSDSSSSSD 682
Query: 533 RRGRQCIRPAEIVASLLEGEENTCGKQKPKENNLKPKFQAFKGVGCLYEKESMKKSLKDS 592
+ ++ E +++ ++ +S + DS
Sbjct: 683 SSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDS----------------SDSSNSNSSDS 726
Query: 593 VASNNKDQ----NSMKHEDPSIISMEDGSPYVNGSLGEVTPCQHAKKANGPNYIQPQKRQ 648
+SN+ D NS D S S S + S + ++ +
Sbjct: 727 DSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSN 786
Query: 649 TTFESQDRKAVSPSSSEKRSKNPISRPLEGKKSLSLSAKTHNIGFDKDSCHSTTKTEASQ 708
+ S D S SS S + S S+ + N DS +S+ +++S
Sbjct: 787 DSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSS- 845
Query: 709 EERSDSSGLTSLKKSPKVSSKDTREIKTDFSLSISNSSDVSAKDKHAEDNEKRLAALEAR 768
+ SD S S +S +S D+ + + S + S+SSD S ++ + ++ ++ +
Sbjct: 846 -DSSDGSDSDSSNRSDSSNSSDSSD--SSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSD 902
Query: 769 QKAKEVQKKLVHNALANL-DGHPEDKPTHIIFGSDSECETEETSTQEQSHPGEEWVKESM 827
+ + + +N D + SDS ++ + + + S+ + S
Sbjct: 903 SDSSDSSNSSDSSDSSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDS----SN 958
Query: 828 GKTSGKLFDSSDDDESDSEDDSNRFKIKPQFEGRAGQKLMDLQSHFGTDDRFRMDSRFLE 887
S DSSD + SDS D SN + D + + D
Sbjct: 959 SSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNS 1018
Query: 888 TDSEEEQEEVNEKKTAEEEELAEEKKKALNVVQSVLQINLSNSTNRGSVAAKKFKDIIHY 947
+DS + N +++ + ++ + + S + SNS++ +
Sbjct: 1019 SDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSS----DSSNSSDSSDSSDSSDSS---- 1070
Query: 948 DPTKQDHATYERKRDDKPKESKAKRKKKREEAEKLPEVSKEMYYNIAMDLKEIFQTTKYT 1007
D + ++ + D S + ++ + S + + D ++ +
Sbjct: 1071 DSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSS 1130
Query: 1008 SEKEEGTPWNEDCGKEKPEEIQDPAALTSDAEQPSGFTFSFFDSDTKDIKEETYRVETVK 1067
+ N + E +SD+ S + S SD+ D + + ++
Sbjct: 1131 DSSDSSDSSNSSDSSDSSESSD-----SSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSD 1185
Query: 1068 PGKIVWQEDPRLQDSSSEEEDVTEETDHRNSSPGEASLLEKETTRFFFFSKNDERLQGSD 1127
D SS+ D ++ +D +SS S +++ S + + SD
Sbjct: 1186 SSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSD 1245
Query: 1128 LFWRGVGSNMSRNSWEARTTNLRMDCRKK 1156
S+ S +S +N D + K
Sbjct: 1246 SSNSSDSSDSSDSSDSTSDSNDESDSQSK 1274
Score = 62.0 bits (149), Expect = 3e-09
Identities = 123/774 (15%), Positives = 265/774 (34%), Gaps = 58/774 (7%)
Query: 364 DSDDDIMRNDREYDSGDTDEIIAMKKNVAKVKNSTEFSQMEKSTKKT---------SFKN 414
DSD + + DS D+D + + + NS++ S S+ + S +
Sbjct: 568 DSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSS 627
Query: 415 RENCELSDHCIKLQKRKSNVESALSHGLKSLNRKSPSHSSSSEDADSASELADSEGGEEY 474
+ + SD K SN + + S + S + S SS+ +DS+ + S+
Sbjct: 628 KSESDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSSDSSDSSDSSSSSDSSNSS 687
Query: 475 NAMMKNCLRVNLTLADLEQLAGSDLKVPNEDTKSDGPETTTQCKFDRGSKSPKTPTGLRR 534
++ + + +D + SD ++ + S+ ++ + D S + +
Sbjct: 688 DSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSS--- 744
Query: 535 GRQCIRPAEIVASLLEGEENTCGKQKPKENNLKPKFQAFKGVGCLYEKESMKKSLKDSVA 594
+ ++ + +++ ++ + +S S +
Sbjct: 745 ------DSSDSSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSS 798
Query: 595 SNNKDQNSMKHEDPSIISMEDGSPYVNGSLGEVTPCQHAKKANGPNYIQPQKRQTTFESQ 654
+++ NS D S S D S + +N + + +S
Sbjct: 799 NSSDSSNSSDSSDSSDSSDSDSS-------------NSSDSSNSSDSSDSSNSSDSSDSS 845
Query: 655 DRKAVSPSSSEKRSKNPISRPLEGKKSLSLSAKTHNIGFDKDSCHSTTKTEASQEERSDS 714
D S S S RS + S S S+ + + +S +S+ +++S SDS
Sbjct: 846 DSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDS 905
Query: 715 SGLTSLKKSPKVSSKDTREIKTDFSLSISNSSDVSAKDKHAEDNEKRLAALEARQKAKEV 774
S ++ S SS + ++ S SNSSD S ++ ++ ++ +
Sbjct: 906 SDSSNSSDSSD-SSNSSDSSESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSS- 963
Query: 775 QKKLVHNALANLDGHPEDKPTHIIFGSDSECETEETSTQEQSHPGEEWVKESMGKTSGKL 834
N+ + D + D SDS ++ + + + S + S S
Sbjct: 964 ------NSSDSSDSNSSD-------SSDSSNSSDSSDSSDSSDSSD----SSDSSNSSDS 1006
Query: 835 FDSSD-DDESDSEDDSNRFKIKPQFEGRAGQKLMDLQSHFGTDDRFRMDSRFLETDSEEE 893
DSSD D S+S D SN + D + D + +DS +
Sbjct: 1007 SDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDS 1066
Query: 894 QEEVNEKKTAEEEELAEEKKKALNVVQSVLQINLSNSTNRGSVAAKKFKDIIHYDPTKQD 953
+ + +++ + +E + + S + +S + S + D D +
Sbjct: 1067 SDSSDSSDSSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSD--SSDSSNSS 1124
Query: 954 HATYERKRDDKPKESKAKRKKKREEAEKLPEVSKEMYYNIAMDLKEIFQTTKYTSEKEEG 1013
++ D S + E+ + S + + D + ++ ++ +
Sbjct: 1125 DSSDSSDSSDSSDSSNSSDSSDSSESSDSSDSSDSSDSSDSSDSSDSSDSSDSSNSSD-- 1182
Query: 1014 TPWNEDCGKEKPEEIQDPAALTSDAEQPSGFTFSFFDSDTKDIKEETYRVETVKPGKIVW 1073
+ D ++ +SD+ S + S SD+ D + + ++ +
Sbjct: 1183 ---SSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSD 1239
Query: 1074 QEDPRLQDSSSEEEDVTEETDHRNSSPGEASLLEKETTRFFFFSKNDERLQGSD 1127
D +SS+ D ++ +D + S E+ K S +D +GSD
Sbjct: 1240 SSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNNNGSDSDSDSEGSD 1293
Score = 57.0 bits (136), Expect = 1e-07
Identities = 105/564 (18%), Positives = 178/564 (31%), Gaps = 21/564 (3%)
Query: 295 NSISDDDTDSEDELRMMIAKEENLQRTTQPSINESESDPFEVVRD--DFKSGVHKLHSLI 352
+S S D +DS D + N + S N S+S D D + S
Sbjct: 698 SSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSD 757
Query: 353 GLGIKNRVSCHDSDDDIMRNDREYDSGDTDEIIAM----KKNVAKVKNSTEFSQMEKSTK 408
N DS D +D S D + N + NS++ S S+
Sbjct: 758 SSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSD 817
Query: 409 KTSFKNRENCELSDHCIKLQKRKSNVESALSHGLKS--LNRKSPSHSSSSEDADSASELA 466
S + ++ SD S+ S S G S NR S+SS S D+ +S +
Sbjct: 818 SDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSS 877
Query: 467 DSEGGEEYNAMMKNCLRVNLTLADLEQLAGSDLKVPNEDTKSDGPETTTQCKFDRGSKSP 526
DS + N + + SD + SD +++ S S
Sbjct: 878 DSSDSSDSNESSNSS-------DSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSSESSNSS 930
Query: 527 KTPTGLRRGRQCIRPAEIVASLLEGEENTCGKQKPKENNLKPKFQAFKGVGCLYEKESMK 586
+S N+ +++ + +S
Sbjct: 931 DNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSDSSDSSD 990
Query: 587 KSLKDSVASNNKDQNSMKHEDPSIISMEDGSPYVNGSLGEVTPCQHAKKANGPNYIQPQK 646
S + ++ +S D S S S + S + ++ +
Sbjct: 991 SSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSDSSDSSD 1050
Query: 647 RQTTFESQDRKAVSPSSSEKRSKNPISRPLEGKKSLSLSAKTHNIGFDKDSCHSTTKTEA 706
+ S D S SS S + S S S+ + N DS S+ +++
Sbjct: 1051 SSDSSNSSDSSDSSDSSDSSDSSD--SSDSSDSSESSDSSDSSNSSDSSDSSDSSDSSDS 1108
Query: 707 SQEERSDSSGLTSLKKSPKVSSKDTREIKTDFSLSISNSSDVSAKDKHAEDNEKRLAALE 766
S + SDSS + S S +D S S S+SSD S++ + D+ + +
Sbjct: 1109 S--DSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNS-SDSSD-SSESSDSSDSSDSSDSSD 1164
Query: 767 ARQKAKEVQKKLVHNALANLDGHPEDKPTHIIFGSDSECETEETSTQEQSHPGEEWVKES 826
+ + N+ + D + SDS ++ + + + S +
Sbjct: 1165 SSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSD 1224
Query: 827 MGKTSGKLFDSSDDDESDSEDDSN 850
+S S D SDS D SN
Sbjct: 1225 SSDSSDSNESSDSSDSSDSSDSSN 1248
Score = 52.0 bits (123), Expect = 3e-06
Identities = 133/822 (16%), Positives = 275/822 (33%), Gaps = 68/822 (8%)
Query: 355 GIKNRVSCHDSDDDIMRNDREYDSGDTDEIIAMKKNVAKVKNSTEFSQMEKSTKKTSFKN 414
G NR + + + D +N D+G +++ ++++ +V S + E + S +N
Sbjct: 147 GATNRSNTNGNTDKNTQNGDVGDAGHNEDVAVVQEDGPQVAGSNNSTDNEDEIIENSCRN 206
Query: 415 RENCELSDHCIKLQKRKSNVESALSHGL---KSLNRKSPSHSSSSEDADSASELADSEGG 471
N I KR E+ ++ G L+ S S + D D D E
Sbjct: 207 EGNTSEITPQIN-SKRNGTKEAEVTPGTGEDAGLDNSDGSPSGNGADEDEDEGSGDDEDE 265
Query: 472 EEYNAMMKNCLRVNLTLADLEQLAGSDLKV-PNEDTKS----DGPETT-TQCKFDRGSKS 525
E N + D + D + N D+K +G E + D+ SKS
Sbjct: 266 EAGNGKDSSNNSKGQEGQDHGKEDDHDSSIGQNSDSKEYYDPEGKEDPHNEVDGDKTSKS 325
Query: 526 PKTPTGLRRGRQCIRPAEIVASLLEGEENTCGKQKPKENNLKPKFQAFKGVGCLYEK--- 582
+ G+ P + + +E + ++ + N K VG +K
Sbjct: 326 EENSAGI--------PEDNGSQRIEDTQKLNHRESKRVENRITKESETHAVGKSQDKGIE 377
Query: 583 ----ESMKKSLKDSVASNNKDQNSMKHEDPSIISMEDGSPYVNGSLGEVT----PCQHAK 634
S +++ V N+ + ED M G V + GEV P Q ++
Sbjct: 378 IKGPSSGNRNITKEVGKGNEGK-----EDKGQHGMILGKGNVK-TQGEVVNIEGPGQKSE 431
Query: 635 KANGPNYIQPQKRQTT-------FESQDRKAVSPSSSEKRSKNPISRPLEGKKSLSLSAK 687
N + + F+ + + P+SS++ + N + S S
Sbjct: 432 PGNKVGHSNTGSDSNSDGYDSYDFDDKSMQGDDPNSSDESNGNDDANSESDNNSSSRGDA 491
Query: 688 THNIGFDKDSCHSTTKTEASQEERSDSSGLTSLKKSPKVSSKDTREIKTDFSLSISNSSD 747
++N KD+ + + A ++ +S + + ++ + K+D S+SSD
Sbjct: 492 SYNSDESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGNDDNDKSDSGKGKSDSSD 551
Query: 748 VSAKD-KHAEDNEKRLAALEARQKAKEVQKKLVHNALANLDGHPEDKPTHIIFGSDSECE 806
+ D ++ D+ + + + ++ + D D S+
Sbjct: 552 SDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSSDSSDSSDSS 611
Query: 807 TEETSTQEQSHPGEEWVKESMGKTSGKLFDSSDDDESDSEDDSNRFKIKPQFEGRAGQKL 866
S+ + ES S DSSD + SDS D+S+ +
Sbjct: 612 DSSDSSDSSDSKSDSSKSESDSSDSDSKSDSSDSNSSDSSDNSD------SSDSSNSSNS 665
Query: 867 MDLQSHFGTDDRFRMDSRFLETDSEEEQEEVNEKKTAEEEELAEEKKKALNVVQSVLQIN 926
D + D +DS + + N ++++ + ++ +
Sbjct: 666 SDSSDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSS-----------D 714
Query: 927 LSNSTNRGSVAAKKFKDIIHYDPTKQDHATYERKRDDKPKESKAKRKKKREEAEKLPEVS 986
S+S+N S + D + ++ + S + ++ + S
Sbjct: 715 SSDSSNSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSS 774
Query: 987 KEMYYNIAMDLKEIFQTTKYTSEKEEGTPWNEDCGKEKPEEIQDPAALTSDAEQPSGFTF 1046
+ + D + ++ + N + + ++ +SD+ S +
Sbjct: 775 DSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDSSD 834
Query: 1047 SFFDSDTKDIKEETYRVETVKPGKIVWQEDPRLQDSSSEEEDVTEETDHRNSSPGEASLL 1106
S SD+ D + + ++ + D SS+ D + +D +SS S
Sbjct: 835 SSNSSDSSDSSDSSDGSDSDSSNR----SDSSNSSDSSDSSDSSNSSDSSDSSDSNESSN 890
Query: 1107 EKETTRFFFFSKNDERLQGSDLFWRGVGSNMSRNSWEARTTN 1148
+++ S N SD S+ S +S + ++N
Sbjct: 891 SSDSSD----SSNSSDSDSSDSSNSSDSSDSSNSSDSSESSN 928
Score = 47.4 bits (111), Expect = 8e-05
Identities = 98/567 (17%), Positives = 186/567 (32%), Gaps = 31/567 (5%)
Query: 295 NSISDDDTDSEDELRMMIAKEENLQRTTQPSINESESDPFEVVRDDFKSGVHKLHSLIGL 354
+S S D +DS D + + + + S N S+S+ D S +S
Sbjct: 749 SSNSSDSSDSSDSSNSSDSSDSSDSSDSSDSSNSSDSNDSSNSSDSSDSS----NSSDSS 804
Query: 355 GIKNRVSCHDSDDDIMRNDREYDSGDTDEIIAMKKNVAKVKNSTEFSQMEKSTKKTSFKN 414
+ DS D N + + + + + +S++ S + S + S +
Sbjct: 805 NSSDSSDSSDSSDSDSSNSSDSSNSSDSSDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNS 864
Query: 415 RENCELSDHCIKLQKRKS---NVESALSHGLKSLNRKSPSHSSSSEDADSASELADSEGG 471
++ + SD S N S S S N S SS +DS+ S+
Sbjct: 865 SDSSDSSDSSNSSDSSDSSDSNESSNSSDSSDSSNSSDSDSSDSSNSSDSSDSSNSSDSS 924
Query: 472 EEYNAMMKNCLRVNLTLADLEQLAGSDLKVPNEDTK-----SDGPETTTQCKFDRGSKSP 526
E N+ + + +D + S + ++ SD ++ + D + S
Sbjct: 925 ESSNSSDNSNSSDSSNSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSNSSDSSDSSNSSD 984
Query: 527 KTPTGLRRGRQCIRPAEIVASLLEGEENTCGKQKPKENNLKPKFQAFKGVGCLYEKESMK 586
+ + + + + +++ +N + +S
Sbjct: 985 SSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSNSSDSSNSSDSSNSSDSSDSSDSSDSSD 1044
Query: 587 KS-LKDSVASNNKDQNSMKHEDPSIISMEDGSPYVNGSLGEVTPCQHAKKANGPNYIQPQ 645
S DS S+N +S + D S + S + + ++ N
Sbjct: 1045 SSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSS-------ESSDSSDSSNSSDSS 1097
Query: 646 KRQTTFESQDRKAVSPSSSEKRSKNPISRPLEGKKSLSLSAKTHNIGFDKDSCHSTTKTE 705
+ +S D S SS S N S S S+ + N DS S+ ++
Sbjct: 1098 DSSDSSDSSDSSDSSDSSDSSDSSN--SSDSSDSSDSSDSSDSSNSSDSSDSSESSDSSD 1155
Query: 706 ASQE-ERSDSSGLT-SLKKSPKVSSKDTREIKTDFSLSISNSSDVSAKDKHAEDNEKRLA 763
+S + SDSS + S S +S D+ + S S+ S S+ + D+
Sbjct: 1156 SSDSSDSSDSSDSSDSSDSSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSD 1215
Query: 764 ALEARQKAKEVQKKLVHNALANLDGHPEDKPTHIIFGSDSECETEETSTQEQSHPGEEWV 823
+ ++ + + + + D ++ SDS ++ TS +
Sbjct: 1216 SSDSSDSSDSSDSSDSNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQS-- 1273
Query: 824 KESMGKTSGKLFDSSDDDESDSEDDSN 850
K G +G SD D DSN
Sbjct: 1274 KSGNGNNNG-----SDSDSDSEGSDSN 1295
>gi|217330641 IWS1 homolog [Homo sapiens]
Length = 819
Score = 61.6 bits (148), Expect = 4e-09
Identities = 109/486 (22%), Positives = 190/486 (39%), Gaps = 68/486 (13%)
Query: 604 KHEDPSIISMEDGSPYVNGSLGEVTPCQHAKKANGPNYIQPQKRQTTFESQDRKAVSPSS 663
+H + EDG P + H + + + E R+ S S
Sbjct: 47 RHSENETSDREDGLPKGH----------HVTDSENDEPLNLNASDSESEELHRQKDSDSE 96
Query: 664 SEKRSKNPIS----RPLEGKKSLSLSAKTHNIGFDKDSCHSTTKTEASQEERSD------ 713
SE+R++ P S + S S S +T + AS E D
Sbjct: 97 SEERAEPPASDSENEDVNQHGSDSESEETRKLPGSDSENEELLNGHASDSENEDVGKHPA 156
Query: 714 -SSGLTSLKKSPKVSSKDTREIKTDFSLSISNSSDV-SAKDKHAEDNEK-RLAALEARQK 770
S + L+KSP S+ +K S S S A D E+ K R++ E+ +
Sbjct: 157 SDSEIEELQKSPASDSETEDALKPQISDSESEEPPRHQASDSENEEPPKPRMSDSESEEL 216
Query: 771 AK------EVQKKLVHNALAN----------LDGHPEDKPTHIIFGSDSE-CETEETSTQ 813
K E ++ H A + D ED P H S++E S
Sbjct: 217 PKPQVSDSESEEPPRHQASDSENEELPKPRISDSESEDPPRHQASDSENEELPKPRISDS 276
Query: 814 EQSHPGEEWVKESMGKTSGKLFDSSDDDE-------SDSE-DDSNRFKIKPQFEGRAGQK 865
E P +S + K S + E SDSE +D++R K KP+ + + ++
Sbjct: 277 ESEDPPRNQASDSENEELPKPRVSDSESEGPQKGPASDSETEDASRHKQKPESDDDSDRE 336
Query: 866 LMDLQSHFGTDDRFRMDS-----RFLETDSEEEQEEVNEKKTAEEEELAEEKKKALNVVQ 920
+ +D F DS +F +DSEEE+ + + + E+E+ EE+K A
Sbjct: 337 NKGEDTEM-QNDSFHSDSHMDRKKFHSSDSEEEEHKKQKMDSDEDEKEGEEEKVAKRKAA 395
Query: 921 SVLQINLSNSTNRGSVAAKKFKDIIHYDPTKQDHATYERKRDDKPKESKAKRKKKREEAE 980
LS+S + +AKK + + D + D + + + +K S ++ + +E ++
Sbjct: 396 V-----LSDSEDEEKASAKKSRVVSDADDSDSDAVSDKSGKREKTIASDSEEEAGKELSD 450
Query: 981 KLPEVSKEMYYNIAMD-------LKEIFQTTKYTSEKEEGTPWNEDCGKEKPEEIQDPAA 1033
K E K+++ + + + +IF + E+EE T +N++ +E+ E Q A
Sbjct: 451 KKNE-EKDLFGSDSESGNEEENLIADIFGESG-DEEEEEFTGFNQEDLEEEKGETQVKEA 508
Query: 1034 LTSDAE 1039
SD++
Sbjct: 509 EDSDSD 514
Score = 60.5 bits (145), Expect = 9e-09
Identities = 125/585 (21%), Positives = 220/585 (37%), Gaps = 64/585 (10%)
Query: 375 EYDSGDTDEIIAMKKNVAKVKNSTE-FSQMEKSTKKTSFKNRENCELSDHCIKLQKRKSN 433
E DSG E +++ S E S+ E S ++ + S++ L S+
Sbjct: 22 ERDSGSDGEDDVNEQHSGSDTGSVERHSENETSDREDGLPKGHHVTDSENDEPLNLNASD 81
Query: 434 VESALSHGLKSLNRKS------PSHSSSSEDADSASELADSE------GGEEYNAMMKNC 481
ES H K + +S P+ S +ED + ++SE G + N + N
Sbjct: 82 SESEELHRQKDSDSESEERAEPPASDSENEDVNQHGSDSESEETRKLPGSDSENEELLNG 141
Query: 482 LRVNLTLADLEQLAGSDLKVPNEDTKSDGPETTTQCKFD---RGSKSPKTPTGLRRGRQC 538
+ D+ + SD ++ E KS ++ T+ S+S + P +
Sbjct: 142 HASDSENEDVGKHPASDSEI-EELQKSPASDSETEDALKPQISDSESEEPPRHQASDSEN 200
Query: 539 IRPAEIVASLLEGEENTCGKQKPKENNLKPKFQAFKGVGCLYEKESMKKSLKDSVASNNK 598
P + S E EE + E+ P+ QA +S + L S+++
Sbjct: 201 EEPPKPRMSDSESEELPKPQVSDSESEEPPRHQA---------SDSENEELPKPRISDSE 251
Query: 599 DQNSMKHEDPSIISMEDGSPYVNGSLGEVTPCQHAKKANGPNYIQPQKRQTTFESQDRKA 658
++ +H+ + E P ++ S E P A + +P+ + E +
Sbjct: 252 SEDPPRHQASDSENEELPKPRISDSESEDPPRNQASDSENEELPKPRVSDSESEGPQKGP 311
Query: 659 VSPSSSEKRSKN---PISRPLEGKKSLSLSAKTHNIGFDKDSC---------------HS 700
S S +E S++ P S +++ + N F DS H
Sbjct: 312 ASDSETEDASRHKQKPESDDDSDRENKGEDTEMQNDSFHSDSHMDRKKFHSSDSEEEEHK 371
Query: 701 TTKTEASQEERSDSSGLTSLKKSPKVSSKDTRE---IKTDFSLSISNSSDVSAKDKHAED 757
K ++ ++E+ + +K+ +S + E K +S ++ SD A +
Sbjct: 372 KQKMDSDEDEKEGEEEKVAKRKAAVLSDSEDEEKASAKKSRVVSDADDSDSDAVSDKSGK 431
Query: 758 NEKRLAALEARQKAKEVQ-KKLVHNALANLD---GHPEDKPTHIIFGSDSECETEETSTQ 813
EK +A+ + KE+ KK L D G+ E+ IFG + E EE +
Sbjct: 432 REKTIASDSEEEAGKELSDKKNEEKDLFGSDSESGNEEENLIADIFGESGDEEEEEFTGF 491
Query: 814 EQSHPGEEWVKESMGKTSGKLFDSSDDDESDSEDDSNRFKIKPQFEGRAGQKLMDLQSHF 873
Q E ++E G+T K + ++SDS+D+ R K F L +S
Sbjct: 492 NQ-----EDLEEEKGETQVK-----EAEDSDSDDNIKRGK-HMDFLSDFEMMLQRKKSMS 540
Query: 874 GTDDRFRMDSRFL-ETDSEEEQEEVNEKKTAEEE-ELAEEKKKAL 916
G R R F+ + D V + AEE+ +L +KK AL
Sbjct: 541 GKRRRNRDGGTFISDADDVVSAMIVKMNEAAEEDRQLNNQKKPAL 585
Score = 43.5 bits (101), Expect = 0.001
Identities = 69/370 (18%), Positives = 133/370 (35%), Gaps = 43/370 (11%)
Query: 800 GSDSECETEETSTQEQSHPGEEWVKESMGKTSGKLFDSSDDDESDSEDDSNRFKIKPQFE 859
GS ETS +E P V +S L S + E + + + + E
Sbjct: 43 GSVERHSENETSDREDGLPKGHHVTDSENDEPLNLNASDSESEELHRQKDSDSESEERAE 102
Query: 860 GRAGQKLMDLQSHFGTDDRFRMDSRFLETDSEEEQEEVNEKKTAEEEELAEEKKKALNVV 919
A + + G+D + +DSE E+ +E E++ + +
Sbjct: 103 PPASDSENEDVNQHGSDSESEETRKLPGSDSENEELLNGHASDSENEDVGKHPASDSEIE 162
Query: 920 QSVLQINLSNSTNRGSVAAKKFKDIIHYDPTKQDHATYERKRDDKPKESKAKRKKKREEA 979
+ LQ + ++ + + D +P + + E + KP+ S + E+
Sbjct: 163 E--LQKSPASDSETEDALKPQISDSESEEPPRHQASDSENEEPPKPRMSDS-------ES 213
Query: 980 EKLPEVSKEMYYNIAMDLKEIFQTTKYTSEKEEGTPWNEDCGKEKPEEIQDPAALTSDAE 1039
E+LP+ S+ E P + EE+ P S++E
Sbjct: 214 EELPK--------------------PQVSDSESEEPPRHQASDSENEELPKPRISDSESE 253
Query: 1040 QPSGFTFSFFDSDTKDIKEETYRVETVKPGKIVWQEDPRLQDSSSEEEDVTEE--TDHRN 1097
P S DS+ +++ + R+ + ++ PR Q S SE E++ + +D +
Sbjct: 254 DPPRHQAS--DSENEELPKP--RISDSES-----EDPPRNQASDSENEELPKPRVSDSES 304
Query: 1098 SSPGEASLLEKETTRFFFFSKNDERLQGSDLFWRGVGSNMSRNSWEARTTNLRMDCRKKH 1157
P + + ET + E SD +G + M +S+ ++ MD +K H
Sbjct: 305 EGPQKGPASDSETEDASRHKQKPESDDDSDRENKGEDTEMQNDSFH---SDSHMDRKKFH 361
Query: 1158 KDAKRKMKPK 1167
+ + K
Sbjct: 362 SSDSEEEEHK 371
Score = 36.2 bits (82), Expect = 0.19
Identities = 70/321 (21%), Positives = 125/321 (38%), Gaps = 56/321 (17%)
Query: 219 KIIKVQKDESSTGSLAMSTRPR---RVIERPPLTQ------QQAAQKRTCDSITPSKSSP 269
+I ++QK +S + +P+ E PP Q ++ + R DS S+ P
Sbjct: 160 EIEELQKSPASDSETEDALKPQISDSESEEPPRHQASDSENEEPPKPRMSDS--ESEELP 217
Query: 270 VP-VSDTQKLKNLPFKTSGLETAK-KRNSISDDDTDSEDELRMMIAKEENLQRTTQPSIN 327
P VSD++ + + S E + + ISD ++SED R + EN + +P I+
Sbjct: 218 KPQVSDSESEEPPRHQASDSENEELPKPRISD--SESEDPPRHQASDSEN-EELPKPRIS 274
Query: 328 ESESDPFEVVRDDFKSGVHKLHSLIGLGIKNRVSCHDSDDDIMRNDREYDSGDTDEIIAM 387
+SES+ R DS+++ + R DS E
Sbjct: 275 DSESED-----------------------PPRNQASDSENEELPKPRVSDS----ESEGP 307
Query: 388 KKNVAKVKNSTEFSQMEKSTKKTSFKNRENCELSDHCIKLQKRKSNVESALSHGLKSLNR 447
+K A + + S+ ++ + +REN + + +++ H ++R
Sbjct: 308 QKGPASDSETEDASRHKQKPESDDDSDREN----------KGEDTEMQNDSFHSDSHMDR 357
Query: 448 KSPSHSSSSEDADSASELADSEGGEEYNAMMKNCLRVNLTLADLEQLAGSDLKVPNEDTK 507
K HSS SE+ + + DS+ E+ K R L+D E + K
Sbjct: 358 KK-FHSSDSEEEEHKKQKMDSDEDEKEGEEEKVAKRKAAVLSDSEDEEKASAK--KSRVV 414
Query: 508 SDGPETTTQCKFDRGSKSPKT 528
SD ++ + D+ K KT
Sbjct: 415 SDADDSDSDAVSDKSGKREKT 435
>gi|87299628 biorientation of chromosomes in cell division 1-like
[Homo sapiens]
Length = 3051
Score = 58.2 bits (139), Expect = 5e-08
Identities = 164/931 (17%), Positives = 330/931 (35%), Gaps = 130/931 (13%)
Query: 228 SSTGSLAMSTRPRRVIERPPLTQQQAAQKRTCDSITPSKSS------------------- 268
+ T + S R + + P T ++RT + + + S
Sbjct: 222 TETSNAKTSERASKKLPSQPTTDTSTDKERTSEDMADKEKSTADSGGEGLETAPKSEEFS 281
Query: 269 --PVPVSD----TQKLKNLPFKTSGL--ETAKKRNSISDDDTDSEDELRMMIAKEENLQR 320
P PV + T++ NL + E+++++N +D D K+E ++
Sbjct: 282 DLPCPVEEIKNYTKEHNNLILLNKDVQQESSEQKNKSTDKGEKKPDSNEKGERKKEKKEK 341
Query: 321 TTQPSINESESDPFEVVRDDFKSGVHKLHSL------------IGLGIKNRVSCHDSDDD 368
T + + +S+ + V+D+ ++ ++ SL G K S DSD D
Sbjct: 342 TEKKFDHSKKSEDTQKVKDEKQAKEKEVESLKLPSEKNSNKAKTVEGTKEDFSLIDSDVD 401
Query: 369 IMRNDREYDSGDTDEIIAMKKNVAKVKNSTEFSQMEKSTKKTSFKNRENCELSDHCIKLQ 428
+ D S T ++ + +++ + +++ + + T KN++N + +
Sbjct: 402 GL-TDITVSSVHTSDLSSFEEDTEEEVVTSDSMEEGEITSDDEEKNKQNKTKTQTSDSSE 460
Query: 429 KRKSNVESALSHGLKSLNRKSPSHSSSSEDADSASELADSEGGEEYNAMMKNCLRVNLTL 488
+ +V A H ++ + S S+D + + S E+ +++ +
Sbjct: 461 GKTKSVRHAYVHKPYLYSK----YYSDSDDELTVEQRRQSIAKEKEERLLRRQINREKLE 516
Query: 489 ADLEQLAGSDLKVPNEDTKSDGPETTTQCKFDRGSKSPKTPTGLRRGRQCIRPAEIVASL 548
+Q A K + TK G + + S PK R ++ ++ +++
Sbjct: 517 EKRKQKAE---KTKSSKTKGQGRSSVDLEESSTKSLEPKAA----RIKEVLKERKVLEKK 569
Query: 549 LEGEENTCGKQKPKENNLKPKFQAFKGVGCLYEKESMKKSLKDSVASNNKDQNSMKHEDP 608
+ + + E N K K Q YE++S K++LK S +H +
Sbjct: 570 VALSKKRKKDSRNVEENSKKKQQ--------YEEDS-KETLKTS-----------EHCEK 609
Query: 609 SIISMEDGSPYVNGSLGEVTPCQHAKKANGPNYIQPQKRQTTFESQDRKAVSP-----SS 663
IS +V+ P + ++ + + K ++ E + ++ S
Sbjct: 610 EKISSSKELKHVHAKSEPSKPARRLSESL--HVVDENKNESKLEREHKRRTSTPVIMEGV 667
Query: 664 SEKRSKNPISRPLEGKKSLSLSAKTHNIGFDKDSCHSTTKTEAS-QEERSDSSGLTSLKK 722
E+ + R +E + + + ST K E +++ S++ L SL K
Sbjct: 668 QEETDTRDVKRQVERSEICTEEPQKQK---------STLKNEKHLKKDDSETPHLKSLLK 718
Query: 723 SPKVSSKDTREI-KTDFSLSISNSSDVSAKDKHAEDNEKRLAALEARQKAKEVQKKLVHN 781
SSK+ E KT +S H +E L + E K +E +K
Sbjct: 719 KEVKSSKEKPEREKTPSEDKLSVKHKYKGDCMHKTGDETELHSSEKGLKVEENIQKQSQQ 778
Query: 782 ALANLDGHPEDKPTHIIFGSDSECETEETSTQEQSHPGEEWVKESMGKTSGKLFDSSDDD 841
+ D E K H S + E +E V++ K +L
Sbjct: 779 TKLSSDDKTERKSKHRNERKLSVLGKDGKPVSEYIIKTDENVRKENNKKERRLSAEKTKA 838
Query: 842 ESDSEDDSNRFKIKPQFEGRAGQKLMDLQSHFGTDDRFRMDSRFLETDSEEEQEEVNEKK 901
E S S+ K + + +S ++D+ MDS + DS + EEV K+
Sbjct: 839 EHKSRRSSDSKIQKDSLGSKQHGITLQRRSESYSEDKCDMDSTNM--DSNLKPEEVVHKE 896
Query: 902 TAEEEELAEEKKKALNVVQSVLQINLSNSTNRGSVAAKKFKDIIHYDPTKQDHATYERKR 961
+ L EEK + L + + K + + TKQ K
Sbjct: 897 KRRTKSLLEEK------------LVLKSKSKTQGKQVKVVETELQEGATKQATTPKPDKE 944
Query: 962 DDKPKESKAKRKKKREEAEKLPEVSKEMYYNIAMDLKEIFQTTKYTSEKEEGTPWNEDCG 1021
+ + K++K + E + E E + E ++ ++++K+
Sbjct: 945 KNTEENDSEKQRKSKVEDKPFEETGVE-------PVLETASSSAHSTQKDSSHRAKLPLA 997
Query: 1022 KEKPEEIQDPAALTSDAEQPSGFTFSFFDSDTKDIKEETYRVETVKPGKIVWQEDPRLQD 1081
KEK + +D + + + G +KDIK++ +
Sbjct: 998 KEKYKSDKDSTSTRLERKLSDGHKSRSLKHSSKDIKKK--------------------DE 1037
Query: 1082 SSSEEEDVTEETDHRNSSPGEASLLEKETTR 1112
+ S+++D E + G +SL+EK+ +R
Sbjct: 1038 NKSDDKDGKEVDSSHEKARGNSSLMEKKLSR 1068
Score = 37.0 bits (84), Expect = 0.11
Identities = 68/320 (21%), Positives = 125/320 (39%), Gaps = 44/320 (13%)
Query: 430 RKSNVESALSHGLKS------------LNRKSPSHSSSSEDA-DSASELADSEGGEEYNA 476
RK N E+ H +++ RK H SSED D ++ DS
Sbjct: 2742 RKDNAEAISGHSVEADPKEVEEEERHMPKRKRKQHYLSSEDEPDDNPDVLDSR----IET 2797
Query: 477 MMKNCLRVNLTLADLEQLAGSDLK-VPNEDTKSDGPETTTQCKFDRGSKSPKTPTGLRRG 535
+ C D ++ DL+ +P T S+ TT++ ++ S TG +
Sbjct: 2798 AQRQCPETEPH--DTKEENSRDLEELPK--TSSETNSTTSRVMEEKDEYSSSETTGEKPE 2853
Query: 536 RQ---CIRPAEIVASLLEGEENTCGKQKPKENNLKPKFQAFKGVGCLYEKESMKKSLKDS 592
+ I+ E ++ + ++ P E LK K + G + ++S S
Sbjct: 2854 QNDDDTIKSQEEDQPIIIKRKRGRPRKYPVETTLKMKDDSKTDTGIVTVEQSPSSSKLKV 2913
Query: 593 VASNNKDQNSMKHEDPSIISMEDGSPYVNGSLGEVTPCQHAKKANGPNYIQPQKRQTTFE 652
+ ++ ++ + ++ SI S +DG + S+ ++ P KR T
Sbjct: 2914 MQTDESNKETANLQERSI-SNDDGEEKIVTSV--------RRRGRKP------KRSLTV- 2957
Query: 653 SQDRKAVSPSSSEKRSKNPISRPLEGKKSLSLSAKTHNIGFDKDSCHSTTKTEASQEERS 712
S D ++ P E++ + +S P+E KK + D+ S +T T S+ +RS
Sbjct: 2958 SDDAESSEP---ERKRQKSVSDPVEDKKEQESDEEEEEEEEDEPSGATTRSTTRSEAQRS 3014
Query: 713 DSSGLTSLKKSPKVSSKDTR 732
+ S+K+ +VS R
Sbjct: 3015 KTQLSPSIKRKREVSPPGAR 3034
Score = 35.8 bits (81), Expect = 0.24
Identities = 53/296 (17%), Positives = 121/296 (40%), Gaps = 34/296 (11%)
Query: 888 TDSEEEQEEVNEKKTAEEEELAEEKKKALNVVQSVLQIN--------LSNSTNRGSVAAK 939
TD+ ++E +E +E+ A+ + L + + + N T +
Sbjct: 243 TDTSTDKERTSEDMADKEKSTADSGGEGLETAPKSEEFSDLPCPVEEIKNYTKEHNNLIL 302
Query: 940 KFKDIIHYDPTKQDHATYERKRDDKPKESKAKRKKKREEAEKLPEVSKEMYYNIAMDLKE 999
KD+ +++ +T + ++ E ++K+K+E+ EK + SK+ + D ++
Sbjct: 303 LNKDVQQESSEQKNKSTDKGEKKPDSNEKGERKKEKKEKTEKKFDHSKK-----SEDTQK 357
Query: 1000 IFQTTKYTSEKEEGT---PWNEDCGKEKPEE--IQDPAALTSDAEQPSGFTFSF-----F 1049
+ + K EKE + P ++ K K E +D + + SD + + T S
Sbjct: 358 V-KDEKQAKEKEVESLKLPSEKNSNKAKTVEGTKEDFSLIDSDVDGLTDITVSSVHTSDL 416
Query: 1050 DSDTKDIKEETYRVETVKPGKIVWQEDPRLQDSSSEEEDVTEETDHRNSSPGEASLLEKE 1109
S +D +EE ++++ G+I ++ + + + ++ + T ++ + + + K
Sbjct: 417 SSFEEDTEEEVVTSDSMEEGEITSDDEEKNKQNKTKTQ--TSDSSEGKTKSVRHAYVHKP 474
Query: 1110 TTRFFFFSKNDERLQGSDLFWRGVGSNMSRNSWEARTTNLRMDCRKKHKDAKRKMK 1165
++S +D+ L V + E LR ++ + KRK K
Sbjct: 475 YLYSKYYSDSDDELT--------VEQRRQSIAKEKEERLLRRQINREKLEEKRKQK 522
Score = 31.6 bits (70), Expect = 4.6
Identities = 57/310 (18%), Positives = 121/310 (39%), Gaps = 58/310 (18%)
Query: 715 SGLTSLKKSPKVSSKDTREIKTDFSLSISNSSDVSAKDKHAE------------DNEKRL 762
SG+ L++ P + ++ SL++ NS + ++ H+E DN + +
Sbjct: 2699 SGIAELQREPLLVNE---------SLNVENSGFRTNEEIHSESYNKGEISSGRKDNAEAI 2749
Query: 763 AALEARQKAKEVQKKLVHNALANLDGH-------PEDKPTHI---IFGSDSEC-ETEETS 811
+ KEV+++ H H P+D P + I + +C ETE
Sbjct: 2750 SGHSVEADPKEVEEEERHMPKRKRKQHYLSSEDEPDDNPDVLDSRIETAQRQCPETEPHD 2809
Query: 812 TQEQ-------------------SHPGEEWVKESMGKTSGKLFDSSDDDESDSEDDSNRF 852
T+E+ S EE + S +T+G+ + +DDD S+++
Sbjct: 2810 TKEENSRDLEELPKTSSETNSTTSRVMEEKDEYSSSETTGEKPEQNDDDTIKSQEEDQPI 2869
Query: 853 KIKPQFEGRAGQKLMDLQSHFGTDDRFRMDSRFLETDSEEEQEEVNEKKTAE-EEELAEE 911
IK + R + +++ D + D+ + + ++ +T E +E A
Sbjct: 2870 IIKRK---RGRPRKYPVETTLKMKDDSKTDTGIVTVEQSPSSSKLKVMQTDESNKETANL 2926
Query: 912 KKKALNVVQSVLQINLSNSTNRGSVAAKKFKDIIHYDPTKQDHATYERKRDDKPKESKAK 971
++++++ +I +++ RG + + D + +K P E K +
Sbjct: 2927 QERSISNDDGEEKI-VTSVRRRGRKPKRSL--TVSDDAESSEPERKRQKSVSDPVEDKKE 2983
Query: 972 RKKKREEAEK 981
++ EE E+
Sbjct: 2984 QESDEEEEEE 2993
Score = 30.8 bits (68), Expect = 7.9
Identities = 61/326 (18%), Positives = 120/326 (36%), Gaps = 50/326 (15%)
Query: 588 SLKDSVASNNKDQNSMKHEDPSIIS-MEDGSPYVNGSLGEVTPCQHAKKANGPNYIQPQK 646
++++S N++ +S + I S +D + ++G E P + ++ + + ++
Sbjct: 2716 NVENSGFRTNEEIHSESYNKGEISSGRKDNAEAISGHSVEADPKEVEEEER--HMPKRKR 2773
Query: 647 RQTTFESQDRKAVSPSSSEKRSKN-----PISRPLEGKKSLSLSAKTHNIGFDKDSCHST 701
+Q S+D +P + R + P + P + K+ S + K S +
Sbjct: 2774 KQHYLSSEDEPDDNPDVLDSRIETAQRQCPETEPHDTKEENSRDLEE----LPKTSSETN 2829
Query: 702 TKTEASQEERSDSSGLTSLKKSPKVSSKDTREIKTDFSLSISNSSDVSAKDKHAEDNEKR 761
+ T EE+ + S + + P+ + DT + S + K K R
Sbjct: 2830 STTSRVMEEKDEYSSSETTGEKPEQNDDDTIK-------SQEEDQPIIIKRKRGRP---R 2879
Query: 762 LAALEARQKAKEVQKKLVHNALANLDGHPEDKPTHIIFGSDSECETEETSTQEQSHP-GE 820
+E K K+ K + ++ P ++ +S ET + S+ GE
Sbjct: 2880 KYPVETTLKMKDDSK--TDTGIVTVEQSPSSSKLKVMQTDESNKETANLQERSISNDDGE 2937
Query: 821 EWVKESM---GKTSGKLFDSSDDDESDSEDDSNRFKIKPQFEGRAGQKLMDLQSHFGTDD 877
E + S+ G+ + SDD ES + + + E + Q
Sbjct: 2938 EKIVTSVRRRGRKPKRSLTVSDDAESSEPERKRQKSVSDPVEDKKEQ------------- 2984
Query: 878 RFRMDSRFLETDSEEEQEEVNEKKTA 903
E+D EEE+EE +E A
Sbjct: 2985 ---------ESDEEEEEEEEDEPSGA 3001
>gi|6631100 natural killer-tumor recognition sequence [Homo sapiens]
Length = 1462
Score = 57.4 bits (137), Expect = 8e-08
Identities = 180/900 (20%), Positives = 315/900 (35%), Gaps = 133/900 (14%)
Query: 203 SKKRRGEFSDFHGPPKKIIKVQKDES---------STGSLAMSTRPR-RVIERPPLTQQQ 252
SKKRR E S P K K S S S A +P R E PP+ + +
Sbjct: 235 SKKRRKEASSSEEPRNKHAMNPKGHSERSDTNEKRSVDSSAKREKPVVRPEEIPPVPENR 294
Query: 253 AAQKRTCDSITPSKSSPVP-----VSDTQ--------KLKNLPFKTSGLETAKKRNSISD 299
+R +T +P VSD + K+K T T + S S+
Sbjct: 295 FLLRRDMPVVTAEPEPKIPDVAPIVSDQKPSVSKSGRKIKGRG--TIRYHTPPRSRSCSE 352
Query: 300 DDTDSEDELRMMIAKEENLQRTTQPSINESESDPFEVVRDDFKSGVHKLHSLIGLGIKNR 359
D D E +E R +P E S ++ D S SL
Sbjct: 353 SDDDDSSETPPHWKEEMQRLRAYRPPSGEKWSKGDKL--SDPCSSRWDERSLSQRSRSWS 410
Query: 360 VSCHDSDDDIMRNDREYDSGDTDEIIAMKKNVAKVKNSTEFSQMEK----------STKK 409
+ + SD R+ + ++ + KK K K+ Q +K S+K
Sbjct: 411 YNGYYSDLSTARHSGHHKKRRKEKKVKHKKKGKKQKHCRRHKQTKKRRILIPSDIESSKS 470
Query: 410 TSFKNRENCEL----------SDHCIKLQKRKSN--VESALSHGLKSLNRKSPSHSSSSE 457
++ + + +C+ S H K KS+ V+S+L+H + R S SHS S
Sbjct: 471 STRRMKSSCDRERSSRSSSLSSHHSSKRDWSKSDKDVQSSLTHSSRDSYR-SKSHSQSYS 529
Query: 458 DADSASELADSEGGEEYNAMMKNCLRVNLTLADLEQLAGSDLKVPNEDTKSDGP-ETTTQ 516
S S A + S K + S P +T +Q
Sbjct: 530 RGSSRSRTASKSSSHSRSRSKSR----------------SSSKSGHRKRASKSPRKTASQ 573
Query: 517 CKFDRGSKS-PKTPTGLRRGRQCIRP--AEIVASLLEGEENTCGKQKPKENNLKPKFQAF 573
++ K+ P T + ++P AE + + + + KP + KP ++
Sbjct: 574 LSENKPVKTEPLRATMAQNENVVVQPVVAENIPVIPLSDSPPPSRWKPGQKPWKPSYERI 633
Query: 574 KG----------VGCLYEKESMKKSLKDSVASNNKDQNSMKHEDPSIISMEDGSPYVNGS 623
+ + Y ++K++ S +S +K + + + + + D S
Sbjct: 634 QEMKAKTTHLLPIQSTYSLANIKET--GSSSSYHKREKNSESDQSTYSKYSDRS------ 685
Query: 624 LGEVTPCQHAKKANGPNYIQPQKRQTTFESQDRKAVSPSSSEKRSKNPISRPLEGKKSLS 683
E +P ++ + +Y + R + S ++ SPSS S+N S + +S S
Sbjct: 686 -SESSPRSRSRSSRSRSYSRSYTRSRSLASSHSRSRSPSS-RSHSRNKYSDHSQCSRSSS 743
Query: 684 LSAKTHNIGFD-KDSCHSTTKTEASQEERSDSSGLTSLKKSPKVSSKDTREIKTDFSLSI 742
++ + + G K S+ K + ++ SS +L S V +D +S S
Sbjct: 744 YTSISSDDGRRAKRRLRSSGKKNSVSHKKHSSSSEKTLH-SKYVKGRDRSSCVRKYSESR 802
Query: 743 SNSSDVSAKDKHAEDNEKRLAALEARQKAKEVQKKLVHNALANLDGHPEDKPTHIIFGSD 802
S S D S+ + + A A++K K+ Q + HN G + K S+
Sbjct: 803 S-SLDYSSDSEQSSVQ----ATQSAQEKEKQGQMERTHNKQEKNRGEEKSK-------SE 850
Query: 803 SECETEETSTQEQ--SHPGEEWVKESMGKTSGKLFDSSDDDESDSEDDSNRFKIKPQFEG 860
EC + T ++ S K +G +DS + E D +S
Sbjct: 851 RECPHSKKRTLKENLSDHLRNGSKPKRKNYAGSKWDSESNSERDVTKNSKN--------- 901
Query: 861 RAGQKLMDLQSHFGTDDRFRMDSRFLETDSEEEQEEVNEKKTAEEEELAEEKKKALNVVQ 920
SH +D + +DSE E E++ K + N
Sbjct: 902 ---------DSHPSSDK----EEGEATSDSESEVSEIHIKVKPTTKSSTNTSLPDDNGAW 948
Query: 921 SVLQINLSNSTNRGSVAAKKFKDIIHYDPTKQDHATYERKRDDKPKESKAKRKKKREEAE 980
+ S S + GS + + P K H + E + + K+ K K K K+++
Sbjct: 949 KSSKQRTSTSDSEGSCSNSENN---RGKPQKHKHGSKENLKREHTKKVKEKLKGKKDKKH 1005
Query: 981 KLPEVSKEMYYNIAMDLKEIFQTTKYTSEKEEGTPWNEDCGKEKPEEIQDPAALTSDAEQ 1040
K P+ + ++ ++ E + + +K+ E E E I+D T + +
Sbjct: 1006 KAPKRKQAFHWQPPLEFGE--EEEEEIDDKQVTQESKEKKVSENNETIKDNILKTEKSSE 1063
Score = 43.1 bits (100), Expect = 0.002
Identities = 110/570 (19%), Positives = 205/570 (35%), Gaps = 67/570 (11%)
Query: 630 CQHAKKANGPNYIQPQKRQTTFESQDRKAVSPSSSEKRSKNPISRPLEGKKSLSLSAKTH 689
C H+KK + R + + A S SE S+ +++ + S +
Sbjct: 853 CPHSKKRTLKENLSDHLRNGSKPKRKNYAGSKWDSESNSERDVTKNSKNDSHPSSDKEEG 912
Query: 690 NIGFDKDSCHSTTKTEASQEERSDSSGLTSLKKSPKV-SSKDTREIKTDFSLSISNSSDV 748
D +S ++ + + SS TSL S R +D S SNS +
Sbjct: 913 EATSDSES--EVSEIHIKVKPTTKSSTNTSLPDDNGAWKSSKQRTSTSDSEGSCSNSENN 970
Query: 749 SAKDKHAEDNEKRLAALEARQKAKEV---QKKLVHNALANLDGHPEDKPTHIIFGSDSEC 805
K + + K E +K KE +K H A P FG + E
Sbjct: 971 RGKPQKHKHGSKENLKREHTKKVKEKLKGKKDKKHKAPKRKQAFHWQPPLE--FGEEEEE 1028
Query: 806 ETEETSTQEQSHP-----GEEWVKESMGKTSGKLFDSSDDDESDSEDDSNRFKIKPQFEG 860
E ++ ++S E +K+++ KT SS++D S D QF
Sbjct: 1029 EIDDKQVTQESKEKKVSENNETIKDNILKTE----KSSEEDLSGKHDTVTVSSDLDQFT- 1083
Query: 861 RAGQKLMDLQSHFGTDDRFRMDSRFLETDSEEEQEEVNEKKTAEEEELAEEKKKALNVVQ 920
+ KL + T++ + + +T + E+ +
Sbjct: 1084 KDDSKLSISPTALNTEENVACLQNIQHVEESVPNGVEDVLQTDDNMEICTPDRS------ 1137
Query: 921 SVLQINLSNSTNRGSVAAKKFKDIIHYDPTKQDHATYERKRDDKPKESKAKRKKKREEAE 980
S ++ ++ + ++ KQD AT + P+ K++ E++
Sbjct: 1138 SPAKVEETSPLGNARLDTPDINIVL-----KQDMAT------EHPQAEVVKQESSMSESK 1186
Query: 981 KLPEVSKEMYYNIAMDLKEIFQTTKYTSEKEEGTPWNEDCGKEKPEE----IQDPAALTS 1036
L EV K+ + ++ K +EK + ++ K KP + + P A TS
Sbjct: 1187 VLGEVGKQDSSSASLASAGESTGKKEVAEKSQINLIDK---KWKPLQGVGNLAAPNAATS 1243
Query: 1037 DAEQPSGFTFSFFDSDTKDIKEETYRVET-----VKPGKIVWQ--------EDPRLQDSS 1083
A + T ++K + R+E V+PG + + PR Q+SS
Sbjct: 1244 SAVEVKVLT------TVPEMKPQGLRIEIKSKNKVRPGSLFDEVRKTARLNRRPRNQESS 1297
Query: 1084 SEEEDVTEETDHRNSSP----GEASLLEKETTRFFFFSKNDERLQGSDLFWRGVGSNMSR 1139
S+E+ + + D ++ SP ++ + TR +S + R + S +R + SR
Sbjct: 1298 SDEQTPSRDDDSQSRSPSRSRSKSETKSRHRTRSVSYSHSRSRSRSSTSSYRSRSYSRSR 1357
Query: 1140 N-SWEAR-TTNLRMDCRKKHKDAKRKMKPK 1167
+ W +R T R + +K + + +
Sbjct: 1358 SRGWYSRGRTRSRSSSYRSYKSHRTSSRSR 1387
Score = 33.1 bits (74), Expect = 1.6
Identities = 77/375 (20%), Positives = 133/375 (35%), Gaps = 55/375 (14%)
Query: 398 TEFSQMEKSTKKTSFKNRENCELSDHCIKLQKRKSNVESALSHGLKSLNRKSPSHSSSSE 457
++ SQ +S+ TS + + K + R S ++++SH S + + HS +
Sbjct: 733 SDHSQCSRSSSYTSISSDDGRRA-----KRRLRSSGKKNSVSHKKHSSSSEKTLHSKYVK 787
Query: 458 DADSAS---ELADSEGGEEYNAMMKNCLRVNLTLADLEQLAGSDLKVPNEDTKSDGPETT 514
D +S + ++S +Y++ D EQ + + E K E T
Sbjct: 788 GRDRSSCVRKYSESRSSLDYSS-------------DSEQSSVQATQSAQEKEKQGQMERT 834
Query: 515 -TQCKFDRGSKSPKTPTGLRRGRQCIRPAEIVASLLEG-EENTCGKQKPKENNLK-PKFQ 571
+ + +RG + K+ R+C P +L E ++ KPK N K+
Sbjct: 835 HNKQEKNRGEEKSKSE------REC--PHSKKRTLKENLSDHLRNGSKPKRKNYAGSKWD 886
Query: 572 AFKGVGCLYEKESMKKSLKDSVASNNKDQNSMKHEDPSIISMED--GSPYVNGSLGEVTP 629
+ E++ K S DS S++K++ + S +S P S P
Sbjct: 887 SESNS----ERDVTKNSKNDSHPSSDKEEGEATSDSESEVSEIHIKVKPTTKSSTNTSLP 942
Query: 630 CQHAKKANGPNYIQPQKRQTTFESQDRKAVSPSSSEKRSKNPISRP--------LEGKKS 681
+ + + + + + P + SK + R L+GKK
Sbjct: 943 DDNGAWKSSKQRTSTSDSEGSCSNSENNRGKPQKHKHGSKENLKREHTKKVKEKLKGKKD 1002
Query: 682 LSLSAKTHNIGFDKDSCHSTTKTEASQEERS--DSSGLTSLKKSPKVSSKDTREIKTDFS 739
K H K + H E +EE D +T K KVS + E D
Sbjct: 1003 -----KKHKAPKRKQAFHWQPPLEFGEEEEEEIDDKQVTQESKEKKVS--ENNETIKDNI 1055
Query: 740 LSISNSSDVSAKDKH 754
L SS+ KH
Sbjct: 1056 LKTEKSSEEDLSGKH 1070
>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
Length = 793
Score = 56.6 bits (135), Expect = 1e-07
Identities = 91/476 (19%), Positives = 182/476 (38%), Gaps = 78/476 (16%)
Query: 623 SLGEVTPCQHAKKANGPNYIQPQKRQTT-----FESQDRKAVSP--SSSEKRSKNPISRP 675
SLG+VT + N N + ++ +TT E D A + E+R + +
Sbjct: 58 SLGQVTD---QVEVNAQNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREERRQKRLQEA 114
Query: 676 LEGKK---------SLSL-SAKTHNIGFDKDSCHSTTKTEASQEERSDSSGLTSLKKSPK 725
LE +K SLSL S + N + ++ K+E+ QE T K K
Sbjct: 115 LERQKEFDPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQK 174
Query: 726 VSSKDTREIKTDFSLSISNSSDVSAKDKHAEDNEK-RLAALEARQKAKEVQKKLVHNALA 784
+D E K + K+K E+ EK + ++ Q V++K +
Sbjct: 175 NDWRDAEENKKE------------DKEKEEEEEEKPKRGSIGENQVEVMVEEKTTES--- 219
Query: 785 NLDGHPEDKPTHIIFGSDSECETEETSTQEQSHPGEEWVKESMGKTSGKLFDSSDDDESD 844
+ T ++ + + +EE +E+ G + + + + D + ++
Sbjct: 220 -------QEETVVMSLKNGQISSEEPKQEEEREQGSDEISHH------EKMEEEDKERAE 266
Query: 845 SEDDSNRFKIKPQFEGRAGQKLMDLQSHFGTDDRFRMDSRFLETDSEEEQEEVNEKKTAE 904
+E + + + + +K+ D ++ +++ R E E+ EK+ AE
Sbjct: 267 AERARLEAEERERIKAEQDKKIADERARIEAEEKAAAQERERREAEERERMREEEKRAAE 326
Query: 905 E-EELAEEKKKALNVVQSVLQINLSNSTNRGSVAAKKFKDIIHYDPTKQDHATYERKR-D 962
E + + EE+K+A Q + + ++ A ER+R
Sbjct: 327 ERQRIKEEEKRAAEERQRIKE--------------------------EEKRAAEERQRIK 360
Query: 963 DKPKESKAKRKKKREEAEKLPEVSKEMYYNIAMDLKEIFQTTKYTSEKEEGTPWNEDCGK 1022
++ K + +R++ R E E+ +V ++ + K Q TK EK E + +
Sbjct: 361 EEEKRAAEERQRARAEEEEKAKVEEQKRNKQLEEKKHAMQETKIKGEKVEQKIEGKWVNE 420
Query: 1023 EKPEEIQDPAALTSDAEQPSGFTFSFFDSDTKDIKEETYRVETVKPGKIVWQEDPR 1078
+K +E + A+ + G ++ K T++ E +K KI ++P+
Sbjct: 421 KKAQEDKLQTAVLKKQGEEKGTKVQAKREKLQEDK-PTFKKEEIKDEKIKKDKEPK 475
>gi|84043963 eukaryotic translation initiation factor 5B [Homo
sapiens]
Length = 1220
Score = 56.6 bits (135), Expect = 1e-07
Identities = 132/612 (21%), Positives = 236/612 (38%), Gaps = 80/612 (13%)
Query: 560 KPKENNLKPKFQAFKGVGCLYEKESMKKSLKDSVASNNKDQNSMKHEDPSIISMEDGSPY 619
KP ENN + +F + K+ KK K S + D +S + ED S + P
Sbjct: 82 KPTENN-EEEFTS---------KDKKKKGQKGKKQSFD-DNDSEELEDKDSKSKKTAKPK 130
Query: 620 V---NGSLGEVTPCQHAKKANGPNYIQPQKRQTTFESQDRKAVSPSSSEKRSKNPISRPL 676
V +GS + + KKA G + QK ++ + + ++RS+ S
Sbjct: 131 VEMYSGSDDDDDFNKLPKKAKG----KAQKSNKKWDGSEEDEDNSKKIKERSRINSSGES 186
Query: 677 EGKKSLSLSAKTHNIGFDKDSCHSTTKTEASQEERSDSSGLTSLKKSPKVSSKDTREIKT 736
+ L ++ G K+ + S E D+S K K+ K
Sbjct: 187 GDESDEFLQSRK---GQKKNQKNKPGPNIESGNEDDDASFKIKTVAQKKAEKKERERKKR 243
Query: 737 DFSLSISNSSDVSAKDKHAEDNEKRLAALEARQKAKEVQKKLVHNALANLDGHPEDKPTH 796
D + AK + ++ E+ + + K KE Q+K + + T
Sbjct: 244 D---------EEKAKLRKLKEKEELETGKKDQSKQKESQRKFEEETVKS----KVTVDTG 290
Query: 797 IIFGSDSECETEETSTQEQSHPGEEWVKESMGKTSGKLFDSSDDDESDSEDDSNRFKIKP 856
+I S+ + ET + E + G++ K+ K K ++ E + + ++ +K
Sbjct: 291 VIPASEEKAETPTAA--EDDNEGDKKKKDKKKKKGEK-----EEKEKEKKKGPSKATVKA 343
Query: 857 QFEGRAGQKLMDLQSHFGTDDRFRMDSRFLETDSEEEQEEVNEKKTAEEEELAEEKKKAL 916
E A K + + ++R + R E +++ ++EE E++ E ++ E+++K
Sbjct: 344 MQEALAKLKEEEERQKREEEERIK---RLEELEAKRKEEERLEQEKRERKKQKEKERKER 400
Query: 917 NVVQSVLQINLSNSTNRGSVAAKKFKDIIHYDPTKQDHATYERKRDDKPKESKAKRKKKR 976
+ L + A K + +D +R P KRKK
Sbjct: 401 LKKEGKLLTKSQREARARAEATLKLLQAQGVEVPSKDSLPKKR-----PIYEDKKRKKIP 455
Query: 977 EEAEKLPEVSKEMYYNIAMDLKEIFQTTKYTSEKEEGTPWNEDCGKEKPEEIQDPAALTS 1036
++ E EVS+ M A+++ E + EKEE P E PEE +D T
Sbjct: 456 QQLES-KEVSESMELCAAVEVME-----QGVPEKEETPPPVE------PEEEED----TE 499
Query: 1037 DAEQPSGFTFSFFDSDTKDIKEETYRVETVKPGKIVWQEDPRLQDSSSEEEDVTEETDHR 1096
DA D + EET +VE K I +E+P ++ EEE+ EE++
Sbjct: 500 DA--------GLDDWEAMASDEETEKVEGNKV-HIEVKENPEEEEEEEEEEEEDEESEEE 550
Query: 1097 NSSPGEASLLEKETTRFFFFSKNDERLQGSDLF---WRGVGSNMSRNSWEARTTNLRMDC 1153
GE+ E + +DE+ G L + + S+ +S + RT R
Sbjct: 551 EEEEGESEGSEGDEED---EKVSDEKDSGKTLDKKPSKEMSSDSEYDSDDDRTKEERAYD 607
Query: 1154 RKKHKDAKRKMK 1165
+ K + KR+++
Sbjct: 608 KAKRRIEKRRLE 619
Score = 49.7 bits (117), Expect = 2e-05
Identities = 78/383 (20%), Positives = 154/383 (40%), Gaps = 44/383 (11%)
Query: 652 ESQDRKAVSPSSSEKRSKN----PISRPLEGKKSLSLSAKTHNIGFDKDSCHSTTKTEAS 707
E + +K+ EK+ ++ I + LE LS + I D+++ + TE +
Sbjct: 34 EQEPQKSKGKKKKEKKKQDFDEDDILKELE-----ELSLEAQGIKADRETV-AVKPTENN 87
Query: 708 QEERSDSSGLTSLKKSPKVS--SKDTREIKTDFSLSISNSSD-VSAKDKHAEDNEKRLAA 764
+EE + +K K S D+ E++ S S + V +D++
Sbjct: 88 EEEFTSKDKKKKGQKGKKQSFDDNDSEELEDKDSKSKKTAKPKVEMYSGSDDDDDFNKLP 147
Query: 765 LEARQKAKEVQKKLVHNALANLDGHPEDKPTHIIFGSDSECETEETSTQEQSHPGEEWVK 824
+A+ KA++ KK DG ED+ S S+ E +E+++
Sbjct: 148 KKAKGKAQKSNKKW--------DGSEEDEDNSKKIKERSRIN----SSGESGDESDEFLQ 195
Query: 825 ESMGKTSGKLFDSSDDDESDSEDDSNRFKIKPQFEGRAGQKLMDLQSHFGTDDRFRMDSR 884
G+ + + ES +EDD FKIK + +A +K +R + D
Sbjct: 196 SRKGQKKNQKNKPGPNIESGNEDDDASFKIKTVAQKKAEKK---------ERERKKRDEE 246
Query: 885 FLETDSEEEQEEVNEKKTAEEEELAEEKKKALNVVQSVLQINLSNSTNRGSVAAKKFKDI 944
+ +E+EE+ K + ++ ++K V+S + + + G + A + K
Sbjct: 247 KAKLRKLKEKEELETGKKDQSKQKESQRKFEEETVKSKVTV------DTGVIPASEEK-- 298
Query: 945 IHYDPTKQDHATYERKRDDKPKESKAKRKKKREEAEKLPEVSKEMYYNIAMDLKEIFQTT 1004
+D ++K+ DK K+ K +K++E+ + + + + LKE +
Sbjct: 299 AETPTAAEDDNEGDKKKKDKKKKKGEKEEKEKEKKKGPSKATVKAMQEALAKLKE--EEE 356
Query: 1005 KYTSEKEEGTPWNEDCGKEKPEE 1027
+ E+EE E+ ++ EE
Sbjct: 357 RQKREEEERIKRLEELEAKRKEE 379
Score = 47.4 bits (111), Expect = 8e-05
Identities = 150/735 (20%), Positives = 275/735 (37%), Gaps = 150/735 (20%)
Query: 292 KKRNSISDDDTDSEDELRMMIA--------KEENLQRTTQPSINESESDPFEVVRDDFKS 343
KK+ + S+D T + +L + A KE+ Q++ E + F+ DD
Sbjct: 3 KKQKNKSEDSTKDDIDLDALAAEIEGAGAAKEQEPQKSKGKKKKEKKKQDFD--EDDILK 60
Query: 344 GVHKLHSLIGLGIK---NRVSCHDSDDDIMRNDREYDSGDTDEIIAM-KKNVAKVKNSTE 399
+ +L SL GIK V+ +++ N+ E+ S D + KK +S E
Sbjct: 61 ELEEL-SLEAQGIKADRETVAVKPTEN----NEEEFTSKDKKKKGQKGKKQSFDDNDSEE 115
Query: 400 FSQMEKSTKKTSFKNRE---NCELSDHCIKLQKR------KSNVESALSHGLKSLNRKSP 450
+ +KKT+ E + D KL K+ KSN + S + ++K
Sbjct: 116 LEDKDSKSKKTAKPKVEMYSGSDDDDDFNKLPKKAKGKAQKSNKKWDGSEEDEDNSKKIK 175
Query: 451 SHS---SSSEDADSASELADSEGGEEYNAMMKNCLRVNLTLADLEQLAGSDLKVPNEDTK 507
S SS E D + E S G++ N K G +++ NED
Sbjct: 176 ERSRINSSGESGDESDEFLQSRKGQKKNQKNK---------------PGPNIESGNEDDD 220
Query: 508 SDGP-ETTTQCKFDRGSKSPKTPTGLRRGRQCIRPAEIVASLLEGEENTCGKQ---KPKE 563
+ +T Q K ++ + K +R + + + L E EE GK+ K KE
Sbjct: 221 ASFKIKTVAQKKAEKKERERK-----KRDEEKAK----LRKLKEKEELETGKKDQSKQKE 271
Query: 564 NNLKPKFQAFKGVGCLYEKESMKKSLKDSVASNNKDQNSMKHEDPSIISMEDGSPYVNGS 623
+ K +E+E++K K +V + + K E P+ + ED +
Sbjct: 272 SQRK------------FEEETVKS--KVTVDTGVIPASEEKAETPT--AAEDDNE----- 310
Query: 624 LGEVTPCQHAKKANGPNYIQPQKRQ----TTFESQDRKAVSPSSSEKRSKNPISRPLEGK 679
G+ KK + +K++ T ++ E+R K ++
Sbjct: 311 -GDKKKKDKKKKKGEKEEKEKEKKKGPSKATVKAMQEALAKLKEEEERQKREEEERIKRL 369
Query: 680 KSLSLSAKTHNIGFDKDSCHSTTKTEASQEERSDSSG--LTSLKKSPKVSSKDTREIKTD 737
+ L K +++ + E ++ER G LT ++ + ++ T ++
Sbjct: 370 EELEAKRKEEE-RLEQEKRERKKQKEKERKERLKKEGKLLTKSQREARARAEATLKLLQA 428
Query: 738 FSLSISNSSDVSAKDKHAEDNEKRLAALEARQKAKEVQKKLVHNALANL--DGHPEDKPT 795
+ + + + K ED +++ + + ++KEV + + A + G PE + T
Sbjct: 429 QGVEVPSKDSLPKKRPIYEDKKRK--KIPQQLESKEVSESMELCAAVEVMEQGVPEKEET 486
Query: 796 HIIFGSDSECETEETSTQEQSHPGEEWVKESMGKTSGKLFDSSDDDESDSEDDSNRFKIK 855
+ E +TE+ ++W E+M +SD++ E + ++K
Sbjct: 487 PPPVEPEEEEDTEDAGL-------DDW--EAM---------ASDEETEKVEGNKVHIEVK 528
Query: 856 PQFEGRAGQKLMDLQSHFGTDDRFRMDSRFLETDSEEEQEEVNEKKTAEEEELAEEKKKA 915
E E + EEE+EE +E+ EEEE E +
Sbjct: 529 ENPE---------------------------EEEEEEEEEEEDEESEEEEEEEGESEGSE 561
Query: 916 LNVVQSVLQINLSNSTNRGSVAAKKFKDIIHYDPTKQDHATYE-RKRDDKPKESKAKRKK 974
+ +S+ + G KK P+K+ + E DD+ KE +A K
Sbjct: 562 GDEEDE----KVSDEKDSGKTLDKK--------PSKEMSSDSEYDSDDDRTKEERAYDKA 609
Query: 975 KREEAEKLPEVSKEM 989
KR ++ E SK +
Sbjct: 610 KRRIEKRRLEHSKNV 624
>gi|21264343 scaffold attachment factor B [Homo sapiens]
Length = 915
Score = 55.8 bits (133), Expect = 2e-07
Identities = 34/134 (25%), Positives = 69/134 (51%), Gaps = 4/134 (2%)
Query: 8 KRLYVGGLSQDISEADLQNQFSRFGEVSDVEIITRKDDQGNPQKVFAYINISVAEADLKK 67
+ +V GLS DL+N FS++G+V +++T G + + ++ +S AE + K
Sbjct: 406 RNFWVSGLSSTTRATDLKNLFSKYGKVVGAKVVTNARSPG--ARCYGFVTMSTAE-EATK 462
Query: 68 CMSVLNKTKWKGGTLQIQLAKESFLHRLAQEREAAKAKKEESTTGNANL-LEKTGGVDFH 126
C++ L+KT+ G + ++ AK + + ++ + KKE+S+ + + L++ D
Sbjct: 463 CINHLHKTELHGKMISVEKAKNEPVGKKTSDKRDSDGKKEKSSNSDRSTNLKRDDKCDRK 522
Query: 127 MKAVPGTEVPGHKN 140
A G + G K+
Sbjct: 523 DDAKKGDDGSGEKS 536
Score = 40.4 bits (93), Expect = 0.010
Identities = 83/395 (21%), Positives = 158/395 (40%), Gaps = 47/395 (11%)
Query: 609 SIISMEDGSPYVNGSLGEVTPCQHAKKANGPNYIQPQKRQTTFESQDRKAVSPSSSEKRS 668
S++++ P GE T C+ P ++P Q++ S+ ++ +SSE+ +
Sbjct: 288 SLLAVVKREPAEQPGDGERTDCE-------PVGLEPAVEQSSAASE----LAEASSEELA 336
Query: 669 KNPISRPLEGKKSLSLSAKTHNIGFDKDSCHSTTKTEASQEERSDSSGLTSLKKSPKVSS 728
+ P P + +K FD D+C+ + + +E S S G SP+ S
Sbjct: 337 EAPTEAPSPEARD----SKEDGRKFDFDACN---EVPPAPKESSTSEGADQKMSSPEDDS 389
Query: 729 KDTREIKTDFSLSISNSSDVSAKDKHAEDNEKRLAALEARQKAKEVQKKLVHNALANLDG 788
DT+ + + S + + L L ++ K V K+V NA +
Sbjct: 390 -DTKRLSKEEKGRSSCGRNFWVSGLSSTTRATDLKNLFSKY-GKVVGAKVVTNARS---- 443
Query: 789 HPEDKPTHIIFGSDSECETE------ETSTQEQSHPGEEWVKESMGK-TSGKLFDSSDDD 841
P + + S +E T+ +T + E+ E +GK TS K +
Sbjct: 444 -PGARCYGFVTMSTAEEATKCINHLHKTELHGKMISVEKAKNEPVGKKTSDKRDSDGKKE 502
Query: 842 ESDSEDDSNRFKIKPQFEGRAGQKLMDLQSHFGTDDRFRMDSRFLETDSEEEQEEVNEKK 901
+S + D S K + + + K D S G + + D + E
Sbjct: 503 KSSNSDRSTNLKRDDKCDRKDDAKKGDDGS--GEKSKDQDDQK---PGPSERSRATKSGS 557
Query: 902 TAEEEELAEEKKKALNVVQ---SVLQINLSNSTNRGSVAAKKFKDIIHYDPTKQ-----D 953
E + +K K + V+ S + S S +R S + +K + ++ +D K+ D
Sbjct: 558 RGTERTVVMDKSKGVPVISVKTSGSKERASKSQDRKSASREK-RSVVSFDKVKEPRKSRD 616
Query: 954 HATYERKRDDKPKESKAKRKKKREEAEKLPEVSKE 988
++ R R+ +E + + + +REE E+L E+++E
Sbjct: 617 SESHSRVRERSEREQRMQAQWEREERERL-EIARE 650
>gi|31657094 anillin, actin binding protein [Homo sapiens]
Length = 1124
Score = 54.3 bits (129), Expect = 7e-07
Identities = 141/667 (21%), Positives = 247/667 (37%), Gaps = 92/667 (13%)
Query: 404 EKSTKKTSFKNRENCELSDHCIKLQKRKSNVESALSHGLKSLNRKSPSHSSSSEDADSAS 463
EKS K S + + ++ + + K VES S SPS S +A
Sbjct: 58 EKSCTKPSPSKKRCSDNTEVEVSNLENKQPVEST------SAKSCSPSPVSPQVQPQAAD 111
Query: 464 ELADSEGGEEYNAMMKNCL--RVNLTLAD-----LEQLAGSDLKVPNEDTKSDGPETTTQ 516
++DS M+ L R+ T A +++LA + N+D D PE++
Sbjct: 112 TISDSVAVPASLLGMRRGLNSRLEATAASSVKTRMQKLAEQRRRWDNDDMTDDIPESSLF 171
Query: 517 CKFDRGSKSPKTPTGL----------RRGRQCIRPAEIVASLLEGEENTCGKQKPKENNL 566
K+ P L RRGR A + A++ E++ K+N++
Sbjct: 172 SPMPSEEKAASPPRPLLSNASATPVGRRGRL----ANLAATICSWEDDV-NHSFAKQNSV 226
Query: 567 KP--------KFQAFKGVGCLYEKESMKK-----SLKDSVASNNKDQNSMKHEDPSIISM 613
+ KF + G S+K+ S +D AS NK +S + + +
Sbjct: 227 QEQPGTACLSKFSSASGASARINSSSVKQEATFCSQRDGDASLNKALSSSADDASLVNAS 286
Query: 614 EDGSPYVNGSLGEVTPCQHAKKANGPNYIQPQKRQTTFESQDRKAVSPSSSEKRSKNPIS 673
S + T AK G N P+ T S + VS + K+ +S
Sbjct: 287 ISSSVKATSPVKSTTSITDAKSCEGQN---PELLPKTPISPLKTGVS----KPIVKSTLS 339
Query: 674 RPLEGKKSLSLSAKTHNIGFDKDSCHSTTKT--------EASQEERSDSSGLTSLKKSPK 725
+ + K LS + DK + T E QE +S ++ ++P
Sbjct: 340 QTVPSKGELSREICLQSQSKDKSTTPGGTGIKPFLERFGERCQEHSKESPARSTPHRTP- 398
Query: 726 VSSKDTREIKTDFSLSISNSSDVSAKDKHAEDNEKRLAALEAR--------------QKA 771
+ + +T+ I+ ++SS + ++ +K LA L R K+
Sbjct: 399 IITPNTKAIQERLFKQDTSSSTTHLAQQLKQERQKELACLRGRFDKGNIWSAEKGGNSKS 458
Query: 772 KEVQ-KKLVHNALANLDGHPEDKPTHIIFGSDSECETE----ETSTQEQSHPGEEWVKES 826
K+++ K+ H L H T + ++ E + +ST+ + E K S
Sbjct: 459 KQLETKQETHCQSTPLKKHQGVSKTQSLPVTEKVTENQIPAKNSSTEPKGFTECEMTKSS 518
Query: 827 MGKTSGKLFDSSDDDESDSEDDSNRFKIKPQFEGRAGQKLMDLQSHFGTDDRFRMDSRFL 886
K + LF D + D KI+ E D+ S +D F
Sbjct: 519 PLKIT--LFLEEDKSLKVTSDPKVEQKIEVIREIEMSVDDDDINSSKVINDLFSDVLEEG 576
Query: 887 ETDSEEEQEEVNEKKTAEEEELAEEKKKALNVVQSVLQINLSNSTNRGSVAAKKFKDIIH 946
E D E+ QEE+++ E +EE++ ALN+ L L+ + G V+ +
Sbjct: 577 ELDMEKSQEEMDQALA----ESSEEQEDALNISSMSLLAPLAQTV--GVVSPESLVS--- 627
Query: 947 YDPTKQDHATYERKRDDKPKESKAKRKK--KREEAEKLPEVSKEMYYNIAMDLKEIFQTT 1004
T + + D+ PK K +R + + E + L +++ Y+I + F+ T
Sbjct: 628 ---TPRLELKDTSRSDESPKPGKFQRTRVPRAESGDSLGSEDRDLLYSIDAYRSQRFKET 684
Query: 1005 KYTSEKE 1011
+ S K+
Sbjct: 685 ERPSIKQ 691
>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
Length = 1020
Score = 53.9 bits (128), Expect = 9e-07
Identities = 118/577 (20%), Positives = 210/577 (36%), Gaps = 77/577 (13%)
Query: 551 GEENTCGKQKPKENNLKPKFQAFKGVGCLYEKESMKKSLKDSVASNNKDQNSMKHEDPSI 610
GEE T K P E P EKE+ K +K+ S + ++ K E S
Sbjct: 497 GEEET--KSPPAEEAASP------------EKEA-KSPVKEEAKSPAEAKSPEKEEAKSP 541
Query: 611 ISMEDGSPYVNGSLGEVTPCQHAK-----KANGPNYIQPQKRQTTFESQDRKAVSPSSSE 665
++ + + E AK +A P ++ ++ + ++ K+ + + S
Sbjct: 542 AEVKSPEKAKSPAKEEAKSPPEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPAEAKSP 601
Query: 666 KRSKNPISR----PLEGKKSLSLSAKTHNIGFDKDSCHSTTKTEASQEERSDSSGLTSLK 721
+++K+P+ P E K + AK+ + S TK EA E++ S K
Sbjct: 602 EKAKSPVKEEAKSPAEAKSPVKEEAKSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAK 661
Query: 722 KSPKVSSKDTREIKTDFSLSISNSSDVSAKDKHAEDNEKRLAALEARQKAKEVQKKLVHN 781
K S E K S S A+ EK + ++ K+ E K V
Sbjct: 662 SPEKAKSPVKAEAK-------SPEKAKSPVKAEAKSPEKAKSPVKEEAKSPEKAKSPVKE 714
Query: 782 ALANLDGHPEDKPTHIIFGSDSECETEETSTQEQSHPGEEWVKESMGKTSGKLFDSSDDD 841
+ PE + + + + + + +E P + E K ++
Sbjct: 715 EAKS----PEKAKSPVKEEAKTPEKAKSPVKEEAKSPEKAKSPEKAKTLDVKSPEAKTPA 770
Query: 842 ESDSEDDSNRFKIKPQFEGRAGQKLMDLQSHFGTDDRFRMDSRFLETD---SEEEQEEVN 898
+ ++ +++F K + + +++S + D++ E + EE + V
Sbjct: 771 KEEARSPADKFPEKAKSPVKE-----EVKSPEKAKSPLKEDAKAPEKEIPKKEEVKSPVK 825
Query: 899 EKKTAEEEELAEEKKKALNVVQSVLQINLSNSTNRGSVAAKKFKDIIHYDPTKQDHATYE 958
E++ +E ++ E KKA ++ A KK + K +
Sbjct: 826 EEEKPQEVKVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKK-------EAPKPKVEEKK 878
Query: 959 RKRDDKPKESKAKRKKKR-EEAEKLPEVSKEMYYNIAMDLKEIFQTTKYTSEKEEGTPWN 1017
+KPKESK + KK+ E+ +K+P KE + E+ + K EK E
Sbjct: 879 EPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKV-----EVKEDAK-PKEKTEVAKKE 932
Query: 1018 EDCGKEKPEEIQDPAALTSDAEQPSGFTFSFFDSDTKDIKEETYRVETVKP--GKIVWQE 1075
D K K E PA A + KD KEE + KP ++
Sbjct: 933 PDDAKAK--EPSKPAEKKEAA------------PEKKDTKEEKAKKPEEKPKTEAKAKED 978
Query: 1076 DPRLQDSSS----EEEDVTEETDHRNSSPGEASLLEK 1108
D L S E+ + + TD ++S P E + +K
Sbjct: 979 DKTLSKEPSKPKAEKAEKSSSTDQKDSKPPEKATEDK 1015
Score = 32.3 bits (72), Expect = 2.7
Identities = 45/235 (19%), Positives = 94/235 (40%), Gaps = 20/235 (8%)
Query: 882 DSRFLETDSEEEQEEVNEKKTAEEEELAEEKKKALNVVQSVLQINLSNSTNRGSVAAKKF 941
+++ E +EEE++E E++ EEE EE+ + + S + K+
Sbjct: 463 ETQVTEEVTEEEEKEAKEEEGKEEEGGEEEE------AEGGEEETKSPPAEEAASPEKEA 516
Query: 942 KDIIHYDPTKQDHATYERKRDDK-PKESKAKRKKK---REEAEKLPEVSKEMYYNIAMDL 997
K + + A K + K P E K+ K K +EEA+ PE + +
Sbjct: 517 KSPVKEEAKSPAEAKSPEKEEAKSPAEVKSPEKAKSPAKEEAKSPPEAK-------SPEK 569
Query: 998 KEIFQTTKYTSEKEEGTPWNEDCGKEKPEEIQDPAALTSDAEQPSGFTFSFFDSDTKDIK 1057
+E + S ++ +P E+ + P E + P S ++ + + + S K+
Sbjct: 570 EEAKSPAEVKSPEKAKSPAKEEA--KSPAEAKSPEKAKSPVKEEAK-SPAEAKSPVKEEA 626
Query: 1058 EETYRVETVKPGKIVWQEDPRLQDSSSEEEDVTEETDHRNSSPGEASLLEKETTR 1112
+ V++ + K +E+ + + + E ++ + SP +A E +
Sbjct: 627 KSPAEVKSPEKAKSPTKEEAKSPEKAKSPEKEEAKSPEKAKSPVKAEAKSPEKAK 681
>gi|33620716 retinoblastoma-binding protein 6 isoform 2 [Homo sapiens]
Length = 1758
Score = 53.9 bits (128), Expect = 9e-07
Identities = 153/799 (19%), Positives = 295/799 (36%), Gaps = 120/799 (15%)
Query: 263 TPSKSSPVPVSDTQKLKNLPFKTSGLETAKKRNSISDDDTDSEDELRMMIAKEENLQRTT 322
TP K+ + Q+ K P K ++ ++ S+ T E++ + K + L
Sbjct: 1053 TPRKAHSKSAKEHQETK--PVKEEKVKKDYSKDVKSEKLTTKEEKAKKPNEKNKPLDNKG 1110
Query: 323 QPSINESESDPFEVVRDDFKSGVHKLHSLIGLGIKNRVSCHDSDDDIMRNDREYDSGDTD 382
+ ++E + V DF+S K+ L I + D + DR +
Sbjct: 1111 EKRKRKTEE---KGVDKDFESSSMKISKLEVTEIVKPSPKRKMEPDTEKMDRTPEK---- 1163
Query: 383 EIIAMKKNVAKVKNSTEFSQMEKSTKKTSFKNR--ENCELSDHCIKLQKRKSNVESALSH 440
+ I++ K+K + E + ST+ S E E + +K +K K V ++
Sbjct: 1164 DKISLSAPAKKIKLNRETGKKIGSTENISNTKEPSEKLESTSSKVKQEKVKGKVRRKVT- 1222
Query: 441 GLKSLNRKSPSHSSSSEDADS----ASELADSEGG-----EEYNAMMKNCLRVNLTLADL 491
G + + ++S+S S + E D++ EEYN N A
Sbjct: 1223 GTEGSSSTLVDYTSTSSTGGSPVRKSEEKTDTKRTVIKTMEEYN---------NDNTAPA 1273
Query: 492 EQLAGSDLKVPNEDTKSDGPETTTQCKFDRGSKSPKTPTGLRRGRQCIRPAEIVASLLEG 551
E + ++VP D E+ + D S P + G +PA ++ ++
Sbjct: 1274 EDVIIM-IQVPQSKWDKDDFESEEE---DVKSTQPISSVG--------KPASVIKNVSTK 1321
Query: 552 EENTCGKQKPKENNLKPKFQAF-KGVGCLYEKESMKKSLKDSVASNNKDQNSMKHEDPSI 610
N K KE+ K Q F K V E ++ +K S S + ++ K D S+
Sbjct: 1322 PSNIV-KYPEKESEPSEKIQKFTKDVS----HEIIQHEVKSSKNSASSEKGKTKDRDYSV 1376
Query: 611 ISMEDGSPYVNGSLGEVTPCQHAKKANGPNYIQPQKRQTTFESQDRKAVSPSSSEKRSKN 670
+ E+ N + Q K++N + Q F+S + + +S+K
Sbjct: 1377 LEKENPEKRKNST-------QPEKESN----LDRLNEQGNFKSLSQSSKEARTSDKHDST 1425
Query: 671 PISRPLEGKKSLSLSAKTHNIGFDKDSCHSTTKTEASQEERSDSSGLTSLKKSPKVSSKD 730
S S K DK + + T + +S + R + + LT K SP +KD
Sbjct: 1426 RAS-----------SNKDFTPNRDKKTDYDT-REYSSSKRRDEKNELTRRKDSPS-RNKD 1472
Query: 731 TREIKTDFSLSISNSSDVSAKDKHAEDNEKRLAALEARQKAKEVQKKLVHNALANLDGHP 790
+ +S K + D K+ + + + + H+ A D
Sbjct: 1473 S-------------ASGQKNKPREERDLPKKGTGDSKKSNSSPSRDRKPHDHKATYDTKR 1519
Query: 791 EDKPTHIIFGSDSECETEETSTQEQSHPGEEWVKESMGKTSGKLFDSSDD----DESDSE 846
++ T + + C+ E E + KES G + + + ++ +
Sbjct: 1520 PNEETKSV--DKNPCKDREKHVLEARNN-----KESSGNKLLYILNPPETQVEKEQITGQ 1572
Query: 847 DDSNRFKIKPQFEGRAGQKLMDLQSHFGTDDRFRMDSRFLETDSEEEQEEVNEKKTAEE- 905
D + K KPQ + S +D D E D E E N EE
Sbjct: 1573 IDKSTVKPKPQ---------LSHSSRLSSDLTRETDEAAFEPDYNESDSESNVSVKEEES 1623
Query: 906 ---------EELAEEKKKALNVVQSVLQINLSNSTNRGSVAAKKFKDIIHYDPTKQDHAT 956
+++ E+ K++L+ +V+Q+ +S + + S + + + H++
Sbjct: 1624 SGNISKDLKDKIVEKAKESLDTA-AVVQVGISRNQSHSSPSVSPSRSHSPSGSQTRSHSS 1682
Query: 957 YERKRDDKPKESKAKRKKKREEAEKLPEVSKEMYYNIAMDLKEIFQTTKYTSEKEEGTPW 1016
+ + +K+KKK++E +K + K + + + ++ K++ +
Sbjct: 1683 SASSAESQD----SKKKKKKKEKKKHKKHKKHKKHKKHAGTEVELEKSQKHKHKKKKSKK 1738
Query: 1017 NEDCGKEKPEEIQDPAALT 1035
N+D KEK ++ Q ++T
Sbjct: 1739 NKDKEKEKEKDDQKVKSVT 1757
Score = 45.4 bits (106), Expect = 3e-04
Identities = 157/825 (19%), Positives = 301/825 (36%), Gaps = 132/825 (16%)
Query: 430 RKSNVESALSHGLKSLNRKSPSHSSSSEDADSASELADSEGGEEYNAMMKNCLRVNLTLA 489
R N+ S L + + + ++ S++ +S + D +G + + +
Sbjct: 856 RSRNIGSNYPEKLSARDGHNQKDNTKSKEKESENAPGDGKGNKHKKHRKRRKGEESEGFL 915
Query: 490 DLEQLAGSDLKVPNEDTKSDGPETTTQCKFDRGSKSPKTPTGLRRGRQCIRPAEIVASLL 549
+ E L S + E T + E T F S+ TP R AE +
Sbjct: 916 NPELLETS--RKSREPTGVE--ENKTDSLFVLPSRDDATPV-----RDEPMDAESITFKS 966
Query: 550 EGEENTCGKQKPKENNLKPKFQAFKGVGCLYEKESMKKSLKDSVASNNKDQNSMKHEDPS 609
E++ + KPK K K + + +KE++ K K + ++ +P
Sbjct: 967 VSEKDKRERDKPKAKGDKTKRK--NDGSAVSKKENIVKPAKGPQEKVDGERERSPRSEPP 1024
Query: 610 IISMEDGSPYVNGSLGEV----------TPCQ-HAKKANGPNYIQPQKRQTTFE--SQDR 656
I ++ +P + + TP + H+K A +P K + + S+D
Sbjct: 1025 IKKAKEETPKTDNTKSSSSSQKDEKITGTPRKAHSKSAKEHQETKPVKEEKVKKDYSKDV 1084
Query: 657 KAVSPSSSEKRSKNPI--SRPLEGKKSLSLSAKTHNIGFDKDSCHST-----------TK 703
K+ ++ E+++K P ++PL+ K KT G DKD S+ K
Sbjct: 1085 KSEKLTTKEEKAKKPNEKNKPLDNKGE-KRKRKTEEKGVDKDFESSSMKISKLEVTEIVK 1143
Query: 704 TEASQEERSDSSGLTSLKKSPKVS-SKDTREIKT--DFSLSISNSSDVSAKDKHAEDNEK 760
++ D+ + + K+S S ++IK + I ++ ++S + +E E
Sbjct: 1144 PSPKRKMEPDTEKMDRTPEKDKISLSAPAKKIKLNRETGKKIGSTENISNTKEPSEKLES 1203
Query: 761 RLAALEARQKAKEVQKKLV-----------HNALANLDGHPEDKPTHIIFGSDSECETEE 809
+ ++ + +V++K+ + + ++ G P K + +T E
Sbjct: 1204 TSSKVKQEKVKGKVRRKVTGTEGSSSTLVDYTSTSSTGGSPVRKSEEKTDTKRTVIKTME 1263
Query: 810 TSTQEQSHPGEE---WVKESMGKTSGKLFDSSDDDESDSEDDSNRFK----IK------- 855
+ + P E+ ++ K F+S ++D ++ S+ K IK
Sbjct: 1264 EYNNDNTAPAEDVIIMIQVPQSKWDKDDFESEEEDVKSTQPISSVGKPASVIKNVSTKPS 1323
Query: 856 -----PQFEGRAGQKLMDLQ---SHFGTDDRFRMDSRFLETD---SEEEQEEVNEKKTAE 904
P+ E +K+ SH + ++ +++ V EK+ E
Sbjct: 1324 NIVKYPEKESEPSEKIQKFTKDVSHEIIQHEVKSSKNSASSEKGKTKDRDYSVLEKENPE 1383
Query: 905 EEELAEEKKKALNVVQSVLQINLSN----------STNRGSVAAKKFKDIIHYDPTKQDH 954
+ + + + +K N+ + Q N + S S A KD K D+
Sbjct: 1384 KRKNSTQPEKESNLDRLNEQGNFKSLSQSSKEARTSDKHDSTRASSNKDFTPNRDKKTDY 1443
Query: 955 ATYE----RKRDDKP------------KESKAKRKKKREEAEKLPEV----SKEMYYNIA 994
T E ++RD+K K+S + +K K E LP+ SK+ + +
Sbjct: 1444 DTREYSSSKRRDEKNELTRRKDSPSRNKDSASGQKNKPREERDLPKKGTGDSKKSNSSPS 1503
Query: 995 MDLKEIFQTTKYTSEKEEGTPWNEDCGKEKPEEIQDPAALTSDAEQPSGFTFSFFDSDTK 1054
D K Y +++ + D K E A + + + +T+
Sbjct: 1504 RDRKPHDHKATYDTKRPNEETKSVDKNPCKDREKHVLEARNNKESSGNKLLYILNPPETQ 1563
Query: 1055 DIKEE-TYRVE--TVKPGKIVWQEDPRLQDSSSEEEDVTEETDHR------NSSPGEASL 1105
KE+ T +++ TVKP P+L SS D+T ETD N S E+++
Sbjct: 1564 VEKEQITGQIDKSTVKP-------KPQLSHSSRLSSDLTRETDEAAFEPDYNESDSESNV 1616
Query: 1106 LEKETTRFFFFSKN---------DERLQGSDLFWRGVGSNMSRNS 1141
KE SK+ E L + + G+ N S +S
Sbjct: 1617 SVKEEESSGNISKDLKDKIVEKAKESLDTAAVVQVGISRNQSHSS 1661
>gi|33620769 retinoblastoma-binding protein 6 isoform 1 [Homo sapiens]
Length = 1792
Score = 53.9 bits (128), Expect = 9e-07
Identities = 153/799 (19%), Positives = 295/799 (36%), Gaps = 120/799 (15%)
Query: 263 TPSKSSPVPVSDTQKLKNLPFKTSGLETAKKRNSISDDDTDSEDELRMMIAKEENLQRTT 322
TP K+ + Q+ K P K ++ ++ S+ T E++ + K + L
Sbjct: 1087 TPRKAHSKSAKEHQETK--PVKEEKVKKDYSKDVKSEKLTTKEEKAKKPNEKNKPLDNKG 1144
Query: 323 QPSINESESDPFEVVRDDFKSGVHKLHSLIGLGIKNRVSCHDSDDDIMRNDREYDSGDTD 382
+ ++E + V DF+S K+ L I + D + DR +
Sbjct: 1145 EKRKRKTEE---KGVDKDFESSSMKISKLEVTEIVKPSPKRKMEPDTEKMDRTPEK---- 1197
Query: 383 EIIAMKKNVAKVKNSTEFSQMEKSTKKTSFKNR--ENCELSDHCIKLQKRKSNVESALSH 440
+ I++ K+K + E + ST+ S E E + +K +K K V ++
Sbjct: 1198 DKISLSAPAKKIKLNRETGKKIGSTENISNTKEPSEKLESTSSKVKQEKVKGKVRRKVT- 1256
Query: 441 GLKSLNRKSPSHSSSSEDADS----ASELADSEGG-----EEYNAMMKNCLRVNLTLADL 491
G + + ++S+S S + E D++ EEYN N A
Sbjct: 1257 GTEGSSSTLVDYTSTSSTGGSPVRKSEEKTDTKRTVIKTMEEYN---------NDNTAPA 1307
Query: 492 EQLAGSDLKVPNEDTKSDGPETTTQCKFDRGSKSPKTPTGLRRGRQCIRPAEIVASLLEG 551
E + ++VP D E+ + D S P + G +PA ++ ++
Sbjct: 1308 EDVIIM-IQVPQSKWDKDDFESEEE---DVKSTQPISSVG--------KPASVIKNVSTK 1355
Query: 552 EENTCGKQKPKENNLKPKFQAF-KGVGCLYEKESMKKSLKDSVASNNKDQNSMKHEDPSI 610
N K KE+ K Q F K V E ++ +K S S + ++ K D S+
Sbjct: 1356 PSNIV-KYPEKESEPSEKIQKFTKDVS----HEIIQHEVKSSKNSASSEKGKTKDRDYSV 1410
Query: 611 ISMEDGSPYVNGSLGEVTPCQHAKKANGPNYIQPQKRQTTFESQDRKAVSPSSSEKRSKN 670
+ E+ N + Q K++N + Q F+S + + +S+K
Sbjct: 1411 LEKENPEKRKNST-------QPEKESN----LDRLNEQGNFKSLSQSSKEARTSDKHDST 1459
Query: 671 PISRPLEGKKSLSLSAKTHNIGFDKDSCHSTTKTEASQEERSDSSGLTSLKKSPKVSSKD 730
S S K DK + + T + +S + R + + LT K SP +KD
Sbjct: 1460 RAS-----------SNKDFTPNRDKKTDYDT-REYSSSKRRDEKNELTRRKDSPS-RNKD 1506
Query: 731 TREIKTDFSLSISNSSDVSAKDKHAEDNEKRLAALEARQKAKEVQKKLVHNALANLDGHP 790
+ +S K + D K+ + + + + H+ A D
Sbjct: 1507 S-------------ASGQKNKPREERDLPKKGTGDSKKSNSSPSRDRKPHDHKATYDTKR 1553
Query: 791 EDKPTHIIFGSDSECETEETSTQEQSHPGEEWVKESMGKTSGKLFDSSDD----DESDSE 846
++ T + + C+ E E + KES G + + + ++ +
Sbjct: 1554 PNEETKSV--DKNPCKDREKHVLEARNN-----KESSGNKLLYILNPPETQVEKEQITGQ 1606
Query: 847 DDSNRFKIKPQFEGRAGQKLMDLQSHFGTDDRFRMDSRFLETDSEEEQEEVNEKKTAEE- 905
D + K KPQ + S +D D E D E E N EE
Sbjct: 1607 IDKSTVKPKPQ---------LSHSSRLSSDLTRETDEAAFEPDYNESDSESNVSVKEEES 1657
Query: 906 ---------EELAEEKKKALNVVQSVLQINLSNSTNRGSVAAKKFKDIIHYDPTKQDHAT 956
+++ E+ K++L+ +V+Q+ +S + + S + + + H++
Sbjct: 1658 SGNISKDLKDKIVEKAKESLDTA-AVVQVGISRNQSHSSPSVSPSRSHSPSGSQTRSHSS 1716
Query: 957 YERKRDDKPKESKAKRKKKREEAEKLPEVSKEMYYNIAMDLKEIFQTTKYTSEKEEGTPW 1016
+ + +K+KKK++E +K + K + + + ++ K++ +
Sbjct: 1717 SASSAESQD----SKKKKKKKEKKKHKKHKKHKKHKKHAGTEVELEKSQKHKHKKKKSKK 1772
Query: 1017 NEDCGKEKPEEIQDPAALT 1035
N+D KEK ++ Q ++T
Sbjct: 1773 NKDKEKEKEKDDQKVKSVT 1791
Score = 45.4 bits (106), Expect = 3e-04
Identities = 157/825 (19%), Positives = 301/825 (36%), Gaps = 132/825 (16%)
Query: 430 RKSNVESALSHGLKSLNRKSPSHSSSSEDADSASELADSEGGEEYNAMMKNCLRVNLTLA 489
R N+ S L + + + ++ S++ +S + D +G + + +
Sbjct: 890 RSRNIGSNYPEKLSARDGHNQKDNTKSKEKESENAPGDGKGNKHKKHRKRRKGEESEGFL 949
Query: 490 DLEQLAGSDLKVPNEDTKSDGPETTTQCKFDRGSKSPKTPTGLRRGRQCIRPAEIVASLL 549
+ E L S + E T + E T F S+ TP R AE +
Sbjct: 950 NPELLETS--RKSREPTGVE--ENKTDSLFVLPSRDDATPV-----RDEPMDAESITFKS 1000
Query: 550 EGEENTCGKQKPKENNLKPKFQAFKGVGCLYEKESMKKSLKDSVASNNKDQNSMKHEDPS 609
E++ + KPK K K + + +KE++ K K + ++ +P
Sbjct: 1001 VSEKDKRERDKPKAKGDKTKRK--NDGSAVSKKENIVKPAKGPQEKVDGERERSPRSEPP 1058
Query: 610 IISMEDGSPYVNGSLGEV----------TPCQ-HAKKANGPNYIQPQKRQTTFE--SQDR 656
I ++ +P + + TP + H+K A +P K + + S+D
Sbjct: 1059 IKKAKEETPKTDNTKSSSSSQKDEKITGTPRKAHSKSAKEHQETKPVKEEKVKKDYSKDV 1118
Query: 657 KAVSPSSSEKRSKNPI--SRPLEGKKSLSLSAKTHNIGFDKDSCHST-----------TK 703
K+ ++ E+++K P ++PL+ K KT G DKD S+ K
Sbjct: 1119 KSEKLTTKEEKAKKPNEKNKPLDNKGE-KRKRKTEEKGVDKDFESSSMKISKLEVTEIVK 1177
Query: 704 TEASQEERSDSSGLTSLKKSPKVS-SKDTREIKT--DFSLSISNSSDVSAKDKHAEDNEK 760
++ D+ + + K+S S ++IK + I ++ ++S + +E E
Sbjct: 1178 PSPKRKMEPDTEKMDRTPEKDKISLSAPAKKIKLNRETGKKIGSTENISNTKEPSEKLES 1237
Query: 761 RLAALEARQKAKEVQKKLV-----------HNALANLDGHPEDKPTHIIFGSDSECETEE 809
+ ++ + +V++K+ + + ++ G P K + +T E
Sbjct: 1238 TSSKVKQEKVKGKVRRKVTGTEGSSSTLVDYTSTSSTGGSPVRKSEEKTDTKRTVIKTME 1297
Query: 810 TSTQEQSHPGEE---WVKESMGKTSGKLFDSSDDDESDSEDDSNRFK----IK------- 855
+ + P E+ ++ K F+S ++D ++ S+ K IK
Sbjct: 1298 EYNNDNTAPAEDVIIMIQVPQSKWDKDDFESEEEDVKSTQPISSVGKPASVIKNVSTKPS 1357
Query: 856 -----PQFEGRAGQKLMDLQ---SHFGTDDRFRMDSRFLETD---SEEEQEEVNEKKTAE 904
P+ E +K+ SH + ++ +++ V EK+ E
Sbjct: 1358 NIVKYPEKESEPSEKIQKFTKDVSHEIIQHEVKSSKNSASSEKGKTKDRDYSVLEKENPE 1417
Query: 905 EEELAEEKKKALNVVQSVLQINLSN----------STNRGSVAAKKFKDIIHYDPTKQDH 954
+ + + + +K N+ + Q N + S S A KD K D+
Sbjct: 1418 KRKNSTQPEKESNLDRLNEQGNFKSLSQSSKEARTSDKHDSTRASSNKDFTPNRDKKTDY 1477
Query: 955 ATYE----RKRDDKP------------KESKAKRKKKREEAEKLPEV----SKEMYYNIA 994
T E ++RD+K K+S + +K K E LP+ SK+ + +
Sbjct: 1478 DTREYSSSKRRDEKNELTRRKDSPSRNKDSASGQKNKPREERDLPKKGTGDSKKSNSSPS 1537
Query: 995 MDLKEIFQTTKYTSEKEEGTPWNEDCGKEKPEEIQDPAALTSDAEQPSGFTFSFFDSDTK 1054
D K Y +++ + D K E A + + + +T+
Sbjct: 1538 RDRKPHDHKATYDTKRPNEETKSVDKNPCKDREKHVLEARNNKESSGNKLLYILNPPETQ 1597
Query: 1055 DIKEE-TYRVE--TVKPGKIVWQEDPRLQDSSSEEEDVTEETDHR------NSSPGEASL 1105
KE+ T +++ TVKP P+L SS D+T ETD N S E+++
Sbjct: 1598 VEKEQITGQIDKSTVKP-------KPQLSHSSRLSSDLTRETDEAAFEPDYNESDSESNV 1650
Query: 1106 LEKETTRFFFFSKN---------DERLQGSDLFWRGVGSNMSRNS 1141
KE SK+ E L + + G+ N S +S
Sbjct: 1651 SVKEEESSGNISKDLKDKIVEKAKESLDTAAVVQVGISRNQSHSS 1695
>gi|56676397 ankyrin repeat domain 11 [Homo sapiens]
Length = 2663
Score = 53.1 bits (126), Expect = 1e-06
Identities = 163/823 (19%), Positives = 285/823 (34%), Gaps = 114/823 (13%)
Query: 252 QAAQKRTCDSITPSKSSPVPVSDTQKLKNLPFKTSGLETAKKRNSISDDDTDSEDELRMM 311
+++++ S PS S +D++ K L K E K + D+ ED+ +
Sbjct: 298 ESSEEEDAPSFAPSSSVDGNNTDSEFEKGLKHKAKNPEPQKATAPVKDEYEFDEDDEQDR 357
Query: 312 IAKEENLQRTTQPSINESESDPFEVVRDDFKSGVHKLHSLIGLGIKNRVSCHDSDDDIMR 371
+ ++ + E++S+ F + K +++ +R+ SD++
Sbjct: 358 VPPVDDKHLLKKDYRKETKSNSFISIPKMEVKSYTKNNTIAPKKASHRILSDTSDEE--- 414
Query: 372 NDREYDSGDTDEIIAMKKNVAKVKNSTEFSQMEKSTKKTSFKNRENCELSDHCIKLQKRK 431
D G +++ + + E S ++ +K K + E ++ KR
Sbjct: 415 -DASVTVGTGEKLRLSAHTILPGSKTREPSNAKQQKEKNKVKKKRKKETKGREVRFGKRS 473
Query: 432 SNVESALSHGLKSLNRKSPSHSSSSEDADSASELADSEGGEEYNAMMKNCLRVNLTLADL 491
K S S SE ++S + DS G CL+ + +
Sbjct: 474 D---------------KFCSSESESESSESGEDDRDSLGSS-------GCLKGSPLVLKD 511
Query: 492 EQLAGSDLKVPNEDTKSDGPETTTQCKFDRGSKSPKTPTGLRRGRQCIRPAEIVASLLEG 551
L S S + D+ +K +T + PA S L
Sbjct: 512 PSLFSSLSASSTSSHGSSAAQKQNPSHTDQHTKHWRTDNW----KTISSPAWSEVSSLSD 567
Query: 552 EENTCGKQKPKENNLKPKFQAFKGVGCLYEKESMKKSLKDSVASNNKDQNSMKHEDPSII 611
T ES S SV S + +H + +
Sbjct: 568 STRT-----------------------RLTSESDYSSEGSSVESLKPVRKRQEHRKRASL 604
Query: 612 SMEDGSPYVNGSLGEV--------------TPCQHAKKANGPNYIQPQKRQTTFESQDRK 657
S E SP+++ + G V T +H K G I + + +F +
Sbjct: 605 S-EKKSPFLSSAEGAVPKLDKEGKVVKKHKTKHKHKNKEKGQCSISQELKLKSFTYEYED 663
Query: 658 AVSPSSSEKRSKNPISRPLEGKKSLSLSAKTHNIGFDKDSCHSTTKTEASQEERSDSSGL 717
+ S +N +S E K + + H F K+ S K E + D L
Sbjct: 664 SKQKSDKAILLENDLST--ENKLKVLKHDRDH---FKKEEKLSKMKLEEKEWLFKDEKSL 718
Query: 718 TSLKKSPKVSSKDTREIKTDFSLSISNSSDVSAKDKHAEDNEKRLAALEARQKAKEVQKK 777
+K + K S+ RE K S + S K+K ++ + RL E ++K+K+ K
Sbjct: 719 KRIKDTNKDISRSFREEK---DRSNKAEKERSLKEKSPKEEKLRLYKEERKKKSKDRPSK 775
Query: 778 LVHNALANLDGHPEDKPTHIIFGSDSECETEETSTQEQSHPGEEWVKESMGKTSGKLFDS 837
L D ++K IF D E +E +E S E K + F
Sbjct: 776 LEKKNDLKEDKISKEKEK--IFKEDKEKLKKEKVYREDSAFDEYCNKNQFLENEDTKFSL 833
Query: 838 SDDDE----SDSEDDSNRFKIKPQFEGRAGQKLMDLQSHFGTDDRFRMDSRFLETDSEEE 893
SDD SD D S FK + ++ D++S + LET E+
Sbjct: 834 SDDQRDRWFSDLSDSSFDFKGEDSWDSPV-TDYRDMKSD-------SVAKLILETVKEDS 885
Query: 894 QEEVNEKKTAEEEELAEE--KKKALNVVQSVLQINLSNSTNRGSVAAKKFKDIIHY---- 947
+E + + E+ + E +KK + L ++ + +K K + Y
Sbjct: 886 KERRRDSRAREKRDYREPFFRKKDRDY--------LDKNSEKRKEQTEKHKSVPGYLSEK 937
Query: 948 DPTKQDHATYERKRDDKPKESKAKR--KKKREEA--EKLPEVSKEMYYNIAMDLK----- 998
D +++ A R R D + K +R + K EEA E+L E E + D
Sbjct: 938 DKKRRESAEAGRDRKDALESCKERRDGRAKPEEAHREELKECGCESGFKDKSDGDFGKGL 997
Query: 999 EIFQTTKYTSEKE-EGTPWNEDCGKEKPEEIQDPAALTSDAEQ 1040
E ++ EKE + P E K KPE ++ ++ +E+
Sbjct: 998 EPWERHHPAREKEKKDGPDKERKEKTKPERYKEKSSDKDKSEK 1040
Score = 47.0 bits (110), Expect = 1e-04
Identities = 146/792 (18%), Positives = 288/792 (36%), Gaps = 86/792 (10%)
Query: 369 IMRNDREYDSGDTDEIIAMKKNVAK--VKNSTEFSQMEKSTKKTSFKNRENCELSDHCIK 426
++++DR++ + +++ MK + K+ +++ + K S RE + S+ K
Sbjct: 686 VLKHDRDHFKKE-EKLSKMKLEEKEWLFKDEKSLKRIKDTNKDISRSFREEKDRSNKAEK 744
Query: 427 LQ--KRKSNVESALSHGLKSLNRKSPSHSSSSEDADSASELADSEGGEEYNAMMKNCLRV 484
+ K KS E L + +KS S E + E S+ E+ K L+
Sbjct: 745 ERSLKEKSPKEEKLRLYKEERKKKSKDRPSKLEKKNDLKEDKISKEKEKIFKEDKEKLKK 804
Query: 485 NLTLAD---LEQLAGSDLKVPNEDTK---SDGPETT-----TQCKFD-RGSKSPKTPTGL 532
+ ++ + + NEDTK SD + FD +G S +P
Sbjct: 805 EKVYREDSAFDEYCNKNQFLENEDTKFSLSDDQRDRWFSDLSDSSFDFKGEDSWDSPVTD 864
Query: 533 RRGRQCIRPAEIVASLLEGEENTCGKQKPKENNLKPKFQAFKGVGCLYEKESMKKSLKDS 592
R + A+++ ++ + K++ +++ + K Y + +K +D
Sbjct: 865 YRDMKSDSVAKLILETVKEDS----KERRRDSRAREKRD--------YREPFFRKKDRDY 912
Query: 593 VASNN---KDQNSMKHEDPSIISMEDGSPYVNGSLGE-----VTPCQHAKKANGPNYIQP 644
+ N+ K+Q P +S +D + G + C+ +
Sbjct: 913 LDKNSEKRKEQTEKHKSVPGYLSEKDKKRRESAEAGRDRKDALESCKERRDGRA------ 966
Query: 645 QKRQTTFESQDRKAVSPSSSEKRSKNPISRPLEG-KKSLSLSAKTHNIGFDKDSCHSTTK 703
K + + ++ S + +S + LE ++ K G DK+ TK
Sbjct: 967 -KPEEAHREELKECGCESGFKDKSDGDFGKGLEPWERHHPAREKEKKDGPDKER-KEKTK 1024
Query: 704 TEASQEERSDSSGLTSLKKSPKVSSKDTREIKTDFSLSISNSSDVSAKDKHAEDNEKRLA 763
E +E+ SD K + K ++ + D + KD H +D E++ +
Sbjct: 1025 PERYKEKSSDKD-----KSEKSILEKCQKDKEFDKCFKEKKDTKEKHKDTHGKDKERKAS 1079
Query: 764 ALEARQKAKEVQKKLVHNALANL--DGHPEDKPTHI--IFGSDSECETEETSTQEQSHPG 819
+ ++K ++ ++ + D ++K +I IF +SE + ++ G
Sbjct: 1080 LDQGKEKKEKAFPGIISEDFSEKKDDKKGKEKSWYIADIFTDESE-DDRDSCMGSGFKMG 1138
Query: 820 EEWVKESMGKTSGKLFDSSDDDESDSEDDSNRFKIKPQFEGRAGQKLMDLQSHFGTDDRF 879
E + +T G L + + E+ + D + K E + ++ D + G D
Sbjct: 1139 E---ASDLPRTDG-LQEKEEGREAYASDRHRKSSDKQHPERQKDKEPRDRRKDRGAADAG 1194
Query: 880 RMDSRFLETDSEEEQEEVNEKKTAEEEELAEEKKKALNVVQSVLQINLSNSTNRGSVAAK 939
R E+ E+ EKK E E +++K +V + + N+ + K
Sbjct: 1195 R-------DKKEKVFEKHKEKKDKESTEKYKDRKDRASVDST------QDKKNKQKLPEK 1241
Query: 940 KFKDIIHYDPTKQDHATYERKRDDKPKESKAKRKKKREEAEKLPEVSKEMYYNIAMDLKE 999
K D K H K K ++S ++ EKL E + Y + D
Sbjct: 1242 AEKKHAAEDKAKSKHKEKSDKEHSKERKSSRSADAEKSLLEKLEEEALHEYREDSNDKIS 1301
Query: 1000 IFQTTKYTSEKEE-------GTPWNEDCGKEKPEEIQDPAALTSDAEQPSGFTFSFFDSD 1052
+ +T +E + E G +KP E A L ++ S S
Sbjct: 1302 EVSSDSFTDRGQEPGLTAFLEVSFTEPPGDDKPRE---SACLPEKLKEKERHRHSSSSSK 1358
Query: 1053 TKDIKEETYRVETVKPGK-IVWQEDPRLQDSSSEEEDVTEETDHRNSSPGEASLLEK--E 1109
+E + + K K ++E +DS E+D E + S +A + ++ +
Sbjct: 1359 KSHDRERAKKEKAEKKEKGEDYKEGGSRKDSGQYEKDFLEADAYGVSYNMKADIEDELDK 1418
Query: 1110 TTRFFFFSKNDE 1121
T F K D+
Sbjct: 1419 TIELFSTEKKDK 1430
Score = 45.1 bits (105), Expect = 4e-04
Identities = 131/699 (18%), Positives = 256/699 (36%), Gaps = 82/699 (11%)
Query: 371 RNDREYDSGDTDEIIAMKKNVAKVKNSTE--------FSQMEKSTKKTSFKNRENCELSD 422
+ DR+Y + KN K K TE S+ +K ++++ R+ + +
Sbjct: 907 KKDRDY----------LDKNSEKRKEQTEKHKSVPGYLSEKDKKRRESAEAGRDRKDALE 956
Query: 423 HCIKLQKRKSNVESALSHGLKSLNRKSPSHSSSSEDADSASELADSEGGEEYNAMMKNCL 482
C + + ++ E A LK +S S D D L E E ++ +
Sbjct: 957 SCKERRDGRAKPEEAHREELKECGCESGFKDKS--DGDFGKGL---EPWERHHPAREK-- 1009
Query: 483 RVNLTLADLEQLAGSDLKVPNEDTKSDGPETTTQCKFDRGSKSPKTPTGLRRGRQCIRPA 542
E+ G D K E TK PE + D+ ++ ++ +
Sbjct: 1010 ---------EKKDGPD-KERKEKTK---PERYKEKSSDKDKSEKSILEKCQKDKEFDKCF 1056
Query: 543 EIVASLLEGEENTCGKQKPKENNL----KPKFQAFKGVGCLYEKESMKKSLKDSVASNNK 598
+ E ++T GK K ++ +L + K +AF G+ + E S KK K
Sbjct: 1057 KEKKDTKEKHKDTHGKDKERKASLDQGKEKKEKAFPGI--ISEDFSEKKDDKKG------ 1108
Query: 599 DQNSMKHEDPSIISMEDGSPYVNGSLGEVTPCQHAKKANGPNYIQPQKRQTTFESQDRKA 658
+ S D ED GS ++ + +G + + R+ + RK+
Sbjct: 1109 KEKSWYIADIFTDESEDDRDSCMGSGFKMGEASDLPRTDGLQE-KEEGREAYASDRHRKS 1167
Query: 659 VSPSSSEK-RSKNPISRPLEGKKSLSLSAKTHNIGFDKDSCHSTTKTEASQEERSDSSGL 717
E+ + K P R + + + K + F+K H K + S E+ D
Sbjct: 1168 SDKQHPERQKDKEPRDRRKDRGAADAGRDKKEKV-FEK---HKEKKDKESTEKYKDRKDR 1223
Query: 718 TSLKKSPKVSSKDTREIKTDFSLSISNSSDVSAKDKHAEDNEKRLAALEARQKAKEVQKK 777
S+ + +K K + + + + K+K +++ K + + K + +K
Sbjct: 1224 ASVDSTQDKKNKQKLPEKAEKKHAAEDKAKSKHKEKSDKEHSKERKSSRSADAEKSLLEK 1283
Query: 778 LVHNALANLDGHPEDKPTHIIFGS--DSECETEETSTQEQSH---PGEEWVKESM----- 827
L AL DK + + S D E T+ E S PG++ +ES
Sbjct: 1284 LEEEALHEYREDSNDKISEVSSDSFTDRGQEPGLTAFLEVSFTEPPGDDKPRESACLPEK 1343
Query: 828 -------GKTSGKLFDSSDDDESDSEDDSNRFKIKPQFEGRAGQKLMDLQSHFGTDDRFR 880
+S S D + + E + K + EG + + + F D +
Sbjct: 1344 LKEKERHRHSSSSSKKSHDRERAKKEKAEKKEKGEDYKEGGSRKDSGQYEKDFLEADAYG 1403
Query: 881 MDSRFLETDSEEEQEEVNEKKTAEEEELAEEKKKALNVVQSVLQ------INLSNSTNRG 934
+ S ++ D E+E ++ E + E+++ + +++ ++ L+ IN+ +
Sbjct: 1404 V-SYNMKADIEDELDKTIELFSTEKKDKNDSEREPSKKIEKELKPYGSSAINILKEKKKR 1462
Query: 935 SVAAKKFKDIIHYDPTKQDHATYERKRDDKPKESKAKRKKKREEAEKLPEVSKEMYYNIA 994
+K++D + RD+ + + ++K + + P V K+ +
Sbjct: 1463 EKHREKWRDEKERHRDRHADGLLRHHRDELLRHHRDEQKPATRDKDSPPRVLKDKSRDEG 1522
Query: 995 MDLKEIFQTTKYT--SEKEEGTPWNEDCGKEKPEEIQDP 1031
L + K+ +EKE+G P G +K +DP
Sbjct: 1523 PRLGDAKLKEKFKDGAEKEKGDPVKMSNGNDKVAPSKDP 1561
>gi|7661936 scaffold attachment factor B2 [Homo sapiens]
Length = 953
Score = 52.8 bits (125), Expect = 2e-06
Identities = 27/101 (26%), Positives = 56/101 (55%), Gaps = 3/101 (2%)
Query: 8 KRLYVGGLSQDISEADLQNQFSRFGEVSDVEIITRKDDQGNPQKVFAYINISVAEADLKK 67
+ L+V GLS DL+N FS++G+V +++T G + + ++ +S ++ + K
Sbjct: 407 RNLWVSGLSSTTRATDLKNLFSKYGKVVGAKVVTNARSPG--ARCYGFVTMSTSD-EATK 463
Query: 68 CMSVLNKTKWKGGTLQIQLAKESFLHRLAQEREAAKAKKEE 108
C+S L++T+ G + ++ AK + +R+ + KKE+
Sbjct: 464 CISHLHRTELHGRMISVEKAKNEPAGKKLSDRKECEVKKEK 504
>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
Length = 1976
Score = 51.2 bits (121), Expect = 6e-06
Identities = 103/464 (22%), Positives = 192/464 (41%), Gaps = 55/464 (11%)
Query: 652 ESQDRKAVSPSSSEKRSKNPISRPLEGKKSLSLSAKTHNIGF-DKDSCHSTTKTEASQEE 710
E +D + + E R+K E KK+L K H D H+T E S++
Sbjct: 1154 ELEDTLDTTAAQQELRTKRE-QEVAELKKALEEETKNHEAQIQDMRQRHATALEELSEQL 1212
Query: 711 RSDSSGLTSLKKSPKVSSKDTREIKTDFSL--SISNSS-------DVSAKDKHAEDNEKR 761
+L+K+ + D +E+ + + + S D ++ HA+ +E
Sbjct: 1213 EQAKRFKANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGD 1272
Query: 762 LAALEARQKAKEVQKKLVHNALANLDGHPEDKPTHIIFGSDSECETEETSTQEQSHPGEE 821
+E +KA ++Q +L N L+ E + I F D+ S + Q +E
Sbjct: 1273 RLRVELAEKASKLQNEL-DNVSTLLE---EAEKKGIKFAKDA------ASLESQLQDTQE 1322
Query: 822 WVKESMGKTSGKLFDSSDDDESDSEDDSNRFKIKPQFEGRAG--QKLMDLQSHFGTDDRF 879
++E +T KL SS + + E +S + + + + E R ++++ LQS D +
Sbjct: 1323 LLQE---ETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQL-ADTKK 1378
Query: 880 RMDSRFLETDSEEEQEEVNEK------KTAEEEELAEEK-KKALNVVQSVLQINLSNSTN 932
++D +S EE ++ K + EE+ LA +K +K N +Q L + +
Sbjct: 1379 KVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRLQQELDDLTVDLDH 1438
Query: 933 RGSVAA------KKFKDIIHYDPTKQDHATYERKRDDKPKESKAKRKKKREEAEKLPEVS 986
+ VA+ KKF ++ + K A Y +RD E++ K K A L E
Sbjct: 1439 QRQVASNLEKKQKKFDQLLAEE--KSISARYAEERDRAEAEAREKETKALSLARALEE-- 1494
Query: 987 KEMYYNIAMDLKEIF--QTTKYTSEKEEGTPWNEDCGKEKPEEIQDPAALTSDAEQPSGF 1044
A++ KE F Q + ++ E+ +D GK E + AL E+
Sbjct: 1495 -------ALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEE-MRT 1546
Query: 1045 TFSFFDSDTKDIKEETYRVE-TVKPGKIVWQEDPRLQDSSSEEE 1087
+ + + ++ R+E ++ K ++ D + +D +EE+
Sbjct: 1547 QLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEK 1590
>gi|42560244 peptidylprolyl isomerase G [Homo sapiens]
Length = 754
Score = 51.2 bits (121), Expect = 6e-06
Identities = 106/497 (21%), Positives = 196/497 (39%), Gaps = 63/497 (12%)
Query: 703 KTEASQEERSDSSGLTSLKKSPK--VSSKDTREIKTDFSLSISNS-SDVSAKDKHAEDNE 759
KT+A+ + ++ L+ + PK V ++ + K+ S S S+S SD S+ + + D+
Sbjct: 158 KTDAASKPFAEVRILSCGELIPKSKVKKEEKKRHKSSSSSSSSSSDSDSSSDSQSSSDSS 217
Query: 760 KRLAALEARQKAKEVQKKLVHNALANLDGHPEDKPTHIIFGSDSECETEETSTQEQSHPG 819
+A E +K+K+ +KK N+ + + K + S+SE E E Q P
Sbjct: 218 DSESATE--EKSKKRKKKHRKNSRKHKKEKKKRKKSKKSASSESEAENLEAQPQSTVRPE 275
Query: 820 E-EWVKES---MGKTSGKLFDSS-DDDESDSEDDSNRFKIKPQ------FEGRAGQKLMD 868
E + E+ M K+ K + + E + E + N +P R+G+K+
Sbjct: 276 EIPPIPENRFLMRKSPPKADEKERKNRERERERECNPPNSQPASYQRRLLVTRSGRKIKG 335
Query: 869 L-QSHFGTDDRFRMDSRFLETDS----EEEQEEVNEKKTAEEEELAEEKKKALNVV---- 919
+ T R R RF +++ +E + + + E + K LN +
Sbjct: 336 RGPRRYRTPSRSRSRDRFRRSETPPHWRQEMQRAQRMRVSSGERWIKGDKSELNEIKENQ 395
Query: 920 QSVLQI---------NLSNSTNRGSVAAKKFKDIIHYDPTKQDHATYERKRDDKPKESKA 970
+S +++ N+S S NR + KK KD H +K+ ++DDK K
Sbjct: 396 RSPVRVKERKITDHRNVSESPNRKNEKEKKVKD--HKSNSKERDIRRNSEKDDKYKNKVK 453
Query: 971 KRKKKREEAEKLPEVSKEMYYNIAMDLKEIFQTTKYTSEKEEGTPWNEDCGKEKPEEIQD 1030
KR K + ++ SKE + D K K + +G KEK + +
Sbjct: 454 KRAKSKSRSK-----SKEKSKSKERDSKHNRNEEKRMRSRSKGRDHENVKEKEKQSDSKG 508
Query: 1031 PAALTSDAEQPSGFTFSFFDSDTKDIKEETYRVETVKPGKIVWQEDPRLQDSSSEEEDVT 1090
S +++ S K ++ ++ + K +E R S S E D+T
Sbjct: 509 KDQERSRSKEKS-----------KQLESKSNEHDHSKS-----KEKDRRAQSRSRECDIT 552
Query: 1091 EETDHRNSSPGEASLLEKETTRFFFFSKNDERLQGSDLF------WRGVGSNMSRNSWEA 1144
+ NS E S + R + + +R + + +R G + SR
Sbjct: 553 KGKHSYNSRTRERSRSRDRSRRVRSRTHDRDRSRSKEYHRYREQEYRRRGRSRSRERRTP 612
Query: 1145 RTTNLRMDCRKKHKDAK 1161
+ D R++ +D++
Sbjct: 613 PGRSRSKDRRRRRRDSR 629
Score = 36.2 bits (82), Expect = 0.19
Identities = 131/680 (19%), Positives = 242/680 (35%), Gaps = 135/680 (19%)
Query: 147 GRVLPVLHLKNQHKRKIIKYDPSKYCHNLKKIGEDFSNTIPISSLTWELEGGNDPMSKKR 206
G ++P +K + K++ S + D S+ SS + + E + SKKR
Sbjct: 175 GELIPKSKVKKEEKKR----HKSSSSSSSSSSDSDSSSDSQSSSDSSDSESATEEKSKKR 230
Query: 207 RGEF---SDFHGPPKKIIKVQKDESSTGSLA--MSTRPRRVI---ERPPLTQQQAAQKRT 258
+ + S H KK K K +S+ S A + +P+ + E PP+ + + ++
Sbjct: 231 KKKHRKNSRKHKKEKKKRKKSKKSASSESEAENLEAQPQSTVRPEEIPPIPENRFLMRK- 289
Query: 259 CDSITPSKSSPVPVSDTQKLKNLPFKTSGLETAKKRNSISDDDTDSEDELRMMIA----- 313
SP P +D ++ KN E ++R + + + R+++
Sbjct: 290 ---------SP-PKADEKERKNR-------ERERERECNPPNSQPASYQRRLLVTRSGRK 332
Query: 314 -KEENLQRTTQPSINESESDPFEVVRDDFKSGVHKLHSLIGLGIKNRVSCHDSDDDIMRN 372
K +R PS + S RD F+ H + R+ +
Sbjct: 333 IKGRGPRRYRTPSRSRS--------RDRFRRSETPPHWRQEMQRAQRMRVSSGE------ 378
Query: 373 DREYDSGDTDEIIAMKKNV-----AKVKNSTEFSQMEKSTKKTSFKNRENCELSDHCIKL 427
+ GD E+ +K+N K + T+ + +S + KN + ++ DH
Sbjct: 379 --RWIKGDKSELNEIKENQRSPVRVKERKITDHRNVSESPNR---KNEKEKKVKDHKSNS 433
Query: 428 QKRKSNVESALSHGLKS-LNRKSPSHSSSSEDADSASELADSEGGEEYNAMMKNCLRVNL 486
++R S K+ + +++ S S S S S+ DS+ M++
Sbjct: 434 KERDIRRNSEKDDKYKNKVKKRAKSKSRSKSKEKSKSKERDSKHNRNEEKRMRS------ 487
Query: 487 TLADLEQLAGSDLKVPNEDTKSDGPETTTQCKFDRGSKSPKTPTGLRRGRQCIRPAEIVA 546
+ G D +E+ K ++ ++ K S+S + +
Sbjct: 488 ------RSKGRD----HENVKEKEKQSDSKGKDQERSRSKEK-----------------S 520
Query: 547 SLLEGEENTCGKQKPKENNLKPKFQAFKGVGCLYEKESMKKSLKDSVASNNKDQNSMKHE 606
LE + N K KE ++ + +S + + NS E
Sbjct: 521 KQLESKSNEHDHSKSKEK----------------DRRAQSRSRECDITKGKHSYNSRTRE 564
Query: 607 DPSIISMEDGSPYVNGSLGEVTPCQHAKKANGPNYIQPQKRQTTFESQDRKAVSPSSSEK 666
D S V T + ++ + + Q+ + S+ R+ +P
Sbjct: 565 RSR---SRDRSRRVRSR----THDRDRSRSKEYHRYREQEYRRRGRSRSRERRTPPG-RS 616
Query: 667 RSKNPISRPLEGKKSLSLSAKTHNIGFDKDSCHSTTKTEASQEERSDSSGLTSLKKSPKV 726
RSK+ R + + S +++ N KD + + ++E S+S K
Sbjct: 617 RSKDRRRRRRDSRSSEREESQSRN----KDKYRNQESKSSHRKENSESEKRMYSKSRDHN 672
Query: 727 SSKDTREIKTD-----FSLSISNSSDVSAKD---KHAEDNEKRLAALEARQKAKEVQKKL 778
SS ++RE K D FS +S D K K+ ED + R + + QK+K +
Sbjct: 673 SSNNSREKKADRDQSPFSKIKQSSQDNELKSSMLKNKEDEKIRSSVEKENQKSKGQENDH 732
Query: 779 VHNALANLD-----GHPEDK 793
VH D G EDK
Sbjct: 733 VHEKNKKFDHESSPGTDEDK 752
>gi|4758172 dentin matrix acidic phosphoprotein 1 isoform 1
precursor [Homo sapiens]
Length = 513
Score = 50.8 bits (120), Expect = 7e-06
Identities = 58/316 (18%), Positives = 132/316 (41%), Gaps = 36/316 (11%)
Query: 599 DQNSMKHEDPSIISMEDGSPYVNGSLGEVTPCQHAKKANGPNYIQPQKRQTTFESQDRKA 658
D M+ +DP I E G+ +N + K + + E+ ++
Sbjct: 211 DDEGMQSDDPESIRSERGNSRMNSA--------------------GMKSKESGENSEQAN 250
Query: 659 VSPSSSEKRSKNPISRPLEGKKSLSLSAKTHNIGFDKDSCHSTTKTEASQEERSDSSGLT 718
S + ++P SR + K +S + D ++ K+++++ S +GL+
Sbjct: 251 TQDSGGSQLLEHP-SRKIFRKSRISEEDDRSEL--DDNNTMEEVKSDSTENSNSRDTGLS 307
Query: 719 SLKKSPKVSSKDTREIKTDFSLSISNSSDVSAKDKHAEDNEKRLAALEARQKAKEVQKKL 778
++ K S++ + K + S S + D + + E N L +++ + E Q+++
Sbjct: 308 QPRRDSKGDSQE--DSKENLSQEESQNVDGPSSESSQEAN------LSSQENSSESQEEV 359
Query: 779 VHNALANLDGHPEDKPTHIIFGSDSECETEETSTQEQSHPGEEWVKESMGKTSGKLFDSS 838
V + + +P+ +++ DS+ +EE S+ SH E +E S + + S
Sbjct: 360 VSESRGD---NPDPTTSYVEDQEDSD-SSEEDSSHTLSHSKSESREEQADSESSESLNFS 415
Query: 839 DDDESDSEDDSNRFKIKPQFEGRAGQKLMDLQSHFGTDDRFRMDSRFLETDSEEEQEEVN 898
++ ED+++ + Q + + + +SH DD DS + DS + + +
Sbjct: 416 EESPESPEDENSSSQEGLQSHSSSAESQSE-ESHSEEDDSDSQDSSRSKEDSNSTESKSS 474
Query: 899 EKKTAEEEELAEEKKK 914
++ + + + E +K
Sbjct: 475 SEEDGQLKNIEIESRK 490
Score = 37.4 bits (85), Expect = 0.084
Identities = 40/188 (21%), Positives = 78/188 (41%), Gaps = 15/188 (7%)
Query: 582 KESMKKSLKDSVASNNKDQNSMKHEDPSIISMEDGSPYVNGSLGEVTPCQHAKKANGPNY 641
+E K++L + N +S ++ ++ S E+ S S EV ++ G N
Sbjct: 318 QEDSKENLSQEESQNVDGPSSESSQEANLSSQENSSE----SQEEVV-----SESRGDN- 367
Query: 642 IQPQKRQTTFESQDRKAVSPSSSEKRSKNPISRPLEGKKSLSLSAKTHNIGFDKDSCHST 701
P + E Q+ S SS E S E ++ + S + ++ F ++S S
Sbjct: 368 --PDPTTSYVEDQED---SDSSEEDSSHTLSHSKSESREEQADSESSESLNFSEESPESP 422
Query: 702 TKTEASQEERSDSSGLTSLKKSPKVSSKDTREIKTDFSLSISNSSDVSAKDKHAEDNEKR 761
+S +E S ++ +S + S++ D S S +S+ +K ED + +
Sbjct: 423 EDENSSSQEGLQSHSSSAESQSEESHSEEDDSDSQDSSRSKEDSNSTESKSSSEEDGQLK 482
Query: 762 LAALEARQ 769
+E+R+
Sbjct: 483 NIEIESRK 490
Score = 34.7 bits (78), Expect = 0.54
Identities = 69/382 (18%), Positives = 143/382 (37%), Gaps = 53/382 (13%)
Query: 788 GHPEDKPTHIIFGSDSECETEETSTQEQSH--PGEEWVKES----------------MGK 829
GH PT + S+S E + S++EQ++ P + E +
Sbjct: 35 GHLAQAPTPPLESSESS-EGSKVSSEEQANEDPSDSTQSEEGLGSDDHQYIYRLAGGFSR 93
Query: 830 TSGKLFDSSDDDESDSEDDS-NRFKIKPQFEGRAGQKLMDLQSHFGTDDRFRMDSRFLET 888
++GK D DDDE DS DD+ P + R L S +DD +
Sbjct: 94 STGKGGDDKDDDEDDSGDDTFGDDDSGPGPKDRQEGGNSRLGSDEDSDDTIQASEESAPQ 153
Query: 889 DSEEEQEEVNEKKTAEEEELAEEKKKALNVVQSVLQINLSNSTNRGSVAAKKFKDIIHYD 948
+ Q+ +E + + E+ + K + + Q + + V + H D
Sbjct: 154 GQDSAQDTTSESRELDNEDRVDSKPEGGDSTQ-------ESESEEHWVGGGSDGESSHGD 206
Query: 949 PTKQDHATYERKRDDKPKESKAKR------------KKKREEAEKLPEVSKEMYYNIAMD 996
++ D E + D P+ +++R K+ E +E+ +
Sbjct: 207 GSELDD---EGMQSDDPESIRSERGNSRMNSAGMKSKESGENSEQANTQDSGGSQLLEHP 263
Query: 997 LKEIFQTTKYTSEKEEGTPWNEDCGKE-KPEEIQDPAALTSDAEQPSGFTFSFFDSDTKD 1055
++IF+ ++ + E + + + +E K + ++ + + QP + D+K+
Sbjct: 264 SRKIFRKSRISEEDDRSELDDNNTMEEVKSDSTENSNSRDTGLSQPRRDSKGDSQEDSKE 323
Query: 1056 --IKEETYRVETVKPGKIVWQEDPRLQDSSSEEEDVTEETDHRNSSP--------GEASL 1105
+EE+ V+ ++SS +E+V E+ N P ++
Sbjct: 324 NLSQEESQNVDGPSSESSQEANLSSQENSSESQEEVVSESRGDNPDPTTSYVEDQEDSDS 383
Query: 1106 LEKETTRFFFFSKNDERLQGSD 1127
E++++ SK++ R + +D
Sbjct: 384 SEEDSSHTLSHSKSESREEQAD 405
Score = 33.9 bits (76), Expect = 0.93
Identities = 50/232 (21%), Positives = 98/232 (42%), Gaps = 29/232 (12%)
Query: 271 PVSDTQKLKNLPFKTSGLETAKKRNSISDDDTDSEDELRMMIAKEENLQRTTQPSINESE 330
P S + N ++G+++ + + +T +++ + R ++ S +
Sbjct: 220 PESIRSERGNSRMNSAGMKSKESGENSEQANTQDSGGSQLLEHPSRKIFRKSRISEEDDR 279
Query: 331 SD-----PFEVVRDDFKSGVHKLHSLIGLGIKNRVSCHDSDDDIMRNDREYDSGDTD--- 382
S+ E V+ D + + GL R S DS +D N + +S + D
Sbjct: 280 SELDDNNTMEEVKSDSTENSNSRDT--GLSQPRRDSKGDSQEDSKENLSQEESQNVDGPS 337
Query: 383 EIIAMKKNVAKVKNSTEFSQMEKSTKK-------TSF-KNRENCELSD----HCIKLQKR 430
+ + N++ +NS+E + S + TS+ +++E+ + S+ H + K
Sbjct: 338 SESSQEANLSSQENSSESQEEVVSESRGDNPDPTTSYVEDQEDSDSSEEDSSHTLSHSKS 397
Query: 431 KSNVESALSHGLKSLN--RKSP-----SHSSSSEDADSASELADSEGGEEYN 475
+S E A S +SLN +SP +SSS E S S A+S+ E ++
Sbjct: 398 ESREEQADSESSESLNFSEESPESPEDENSSSQEGLQSHSSSAESQSEESHS 449
Score = 31.2 bits (69), Expect = 6.0
Identities = 34/160 (21%), Positives = 67/160 (41%), Gaps = 14/160 (8%)
Query: 207 RGEFSDFHGPPKKIIKVQKDESSTGSLAMSTRPRRVIERPPLTQQQAAQKRTCDSITPSK 266
RG+ D P ++ Q+D S+ + T E ++++ A + +S+ S+
Sbjct: 364 RGDNPD---PTTSYVEDQEDSDSSEEDSSHTLSHSKSE----SREEQADSESSESLNFSE 416
Query: 267 SSPVPVSD--TQKLKNLPFKTSGLETAKKRNSISDDDTDSEDELRMMIAKEENLQRTTQP 324
SP D + + L +S E+ + + +DD+DS+D R +E+ T
Sbjct: 417 ESPESPEDENSSSQEGLQSHSSSAESQSEESHSEEDDSDSQDSSR----SKEDSNSTESK 472
Query: 325 SINESESDPFEVVRDDFKSGVHKLHSLIGLGIKNRVSCHD 364
S +E + + + K V H+ +G ++ C D
Sbjct: 473 SSSEEDGQLKNIEIESRKLTVDAYHNK-PIGDQDDNDCQD 511
>gi|121256621 dentin matrix acidic phosphoprotein 1 isoform 2
precursor [Homo sapiens]
Length = 497
Score = 50.8 bits (120), Expect = 7e-06
Identities = 58/316 (18%), Positives = 132/316 (41%), Gaps = 36/316 (11%)
Query: 599 DQNSMKHEDPSIISMEDGSPYVNGSLGEVTPCQHAKKANGPNYIQPQKRQTTFESQDRKA 658
D M+ +DP I E G+ +N + K + + E+ ++
Sbjct: 195 DDEGMQSDDPESIRSERGNSRMNSA--------------------GMKSKESGENSEQAN 234
Query: 659 VSPSSSEKRSKNPISRPLEGKKSLSLSAKTHNIGFDKDSCHSTTKTEASQEERSDSSGLT 718
S + ++P SR + K +S + D ++ K+++++ S +GL+
Sbjct: 235 TQDSGGSQLLEHP-SRKIFRKSRISEEDDRSEL--DDNNTMEEVKSDSTENSNSRDTGLS 291
Query: 719 SLKKSPKVSSKDTREIKTDFSLSISNSSDVSAKDKHAEDNEKRLAALEARQKAKEVQKKL 778
++ K S++ + K + S S + D + + E N L +++ + E Q+++
Sbjct: 292 QPRRDSKGDSQE--DSKENLSQEESQNVDGPSSESSQEAN------LSSQENSSESQEEV 343
Query: 779 VHNALANLDGHPEDKPTHIIFGSDSECETEETSTQEQSHPGEEWVKESMGKTSGKLFDSS 838
V + + +P+ +++ DS+ +EE S+ SH E +E S + + S
Sbjct: 344 VSESRGD---NPDPTTSYVEDQEDSD-SSEEDSSHTLSHSKSESREEQADSESSESLNFS 399
Query: 839 DDDESDSEDDSNRFKIKPQFEGRAGQKLMDLQSHFGTDDRFRMDSRFLETDSEEEQEEVN 898
++ ED+++ + Q + + + +SH DD DS + DS + + +
Sbjct: 400 EESPESPEDENSSSQEGLQSHSSSAESQSE-ESHSEEDDSDSQDSSRSKEDSNSTESKSS 458
Query: 899 EKKTAEEEELAEEKKK 914
++ + + + E +K
Sbjct: 459 SEEDGQLKNIEIESRK 474
Score = 37.4 bits (85), Expect = 0.084
Identities = 40/188 (21%), Positives = 78/188 (41%), Gaps = 15/188 (7%)
Query: 582 KESMKKSLKDSVASNNKDQNSMKHEDPSIISMEDGSPYVNGSLGEVTPCQHAKKANGPNY 641
+E K++L + N +S ++ ++ S E+ S S EV ++ G N
Sbjct: 302 QEDSKENLSQEESQNVDGPSSESSQEANLSSQENSSE----SQEEVV-----SESRGDN- 351
Query: 642 IQPQKRQTTFESQDRKAVSPSSSEKRSKNPISRPLEGKKSLSLSAKTHNIGFDKDSCHST 701
P + E Q+ S SS E S E ++ + S + ++ F ++S S
Sbjct: 352 --PDPTTSYVEDQED---SDSSEEDSSHTLSHSKSESREEQADSESSESLNFSEESPESP 406
Query: 702 TKTEASQEERSDSSGLTSLKKSPKVSSKDTREIKTDFSLSISNSSDVSAKDKHAEDNEKR 761
+S +E S ++ +S + S++ D S S +S+ +K ED + +
Sbjct: 407 EDENSSSQEGLQSHSSSAESQSEESHSEEDDSDSQDSSRSKEDSNSTESKSSSEEDGQLK 466
Query: 762 LAALEARQ 769
+E+R+
Sbjct: 467 NIEIESRK 474
Score = 35.4 bits (80), Expect = 0.32
Identities = 65/365 (17%), Positives = 134/365 (36%), Gaps = 35/365 (9%)
Query: 788 GHPEDKPTHIIFGSDSECETE-ETSTQEQSHPGEEWVKESMGKTSGKLFDSSDDDESDSE 846
GH PT + D T+ E H + +++GK D DDDE DS
Sbjct: 35 GHLAQAPTPPLANEDPSDSTQSEEGLGSDDHQYIYRLAGGFSRSTGKGGDDKDDDEDDSG 94
Query: 847 DDS-NRFKIKPQFEGRAGQKLMDLQSHFGTDDRFRMDSRFLETDSEEEQEEVNEKKTAEE 905
DD+ P + R L S +DD + + Q+ +E + +
Sbjct: 95 DDTFGDDDSGPGPKDRQEGGNSRLGSDEDSDDTIQASEESAPQGQDSAQDTTSESRELDN 154
Query: 906 EELAEEKKKALNVVQSVLQINLSNSTNRGSVAAKKFKDIIHYDPTKQDHATYERKRDDKP 965
E+ + K + + Q + + V + H D ++ D E + D P
Sbjct: 155 EDRVDSKPEGGDSTQ-------ESESEEHWVGGGSDGESSHGDGSELDD---EGMQSDDP 204
Query: 966 KESKAKR------------KKKREEAEKLPEVSKEMYYNIAMDLKEIFQTTKYTSEKEEG 1013
+ +++R K+ E +E+ + ++IF+ ++ + E +
Sbjct: 205 ESIRSERGNSRMNSAGMKSKESGENSEQANTQDSGGSQLLEHPSRKIFRKSRISEEDDRS 264
Query: 1014 TPWNEDCGKE-KPEEIQDPAALTSDAEQPSGFTFSFFDSDTKD--IKEETYRVETVKPGK 1070
+ + +E K + ++ + + QP + D+K+ +EE+ V+
Sbjct: 265 ELDDNNTMEEVKSDSTENSNSRDTGLSQPRRDSKGDSQEDSKENLSQEESQNVDGPSSES 324
Query: 1071 IVWQEDPRLQDSSSEEEDVTEETDHRNSSP--------GEASLLEKETTRFFFFSKNDER 1122
++SS +E+V E+ N P ++ E++++ SK++ R
Sbjct: 325 SQEANLSSQENSSESQEEVVSESRGDNPDPTTSYVEDQEDSDSSEEDSSHTLSHSKSESR 384
Query: 1123 LQGSD 1127
+ +D
Sbjct: 385 EEQAD 389
Score = 33.9 bits (76), Expect = 0.93
Identities = 50/232 (21%), Positives = 98/232 (42%), Gaps = 29/232 (12%)
Query: 271 PVSDTQKLKNLPFKTSGLETAKKRNSISDDDTDSEDELRMMIAKEENLQRTTQPSINESE 330
P S + N ++G+++ + + +T +++ + R ++ S +
Sbjct: 204 PESIRSERGNSRMNSAGMKSKESGENSEQANTQDSGGSQLLEHPSRKIFRKSRISEEDDR 263
Query: 331 SD-----PFEVVRDDFKSGVHKLHSLIGLGIKNRVSCHDSDDDIMRNDREYDSGDTD--- 382
S+ E V+ D + + GL R S DS +D N + +S + D
Sbjct: 264 SELDDNNTMEEVKSDSTENSNSRDT--GLSQPRRDSKGDSQEDSKENLSQEESQNVDGPS 321
Query: 383 EIIAMKKNVAKVKNSTEFSQMEKSTKK-------TSF-KNRENCELSD----HCIKLQKR 430
+ + N++ +NS+E + S + TS+ +++E+ + S+ H + K
Sbjct: 322 SESSQEANLSSQENSSESQEEVVSESRGDNPDPTTSYVEDQEDSDSSEEDSSHTLSHSKS 381
Query: 431 KSNVESALSHGLKSLN--RKSP-----SHSSSSEDADSASELADSEGGEEYN 475
+S E A S +SLN +SP +SSS E S S A+S+ E ++
Sbjct: 382 ESREEQADSESSESLNFSEESPESPEDENSSSQEGLQSHSSSAESQSEESHS 433
Score = 31.2 bits (69), Expect = 6.0
Identities = 34/160 (21%), Positives = 67/160 (41%), Gaps = 14/160 (8%)
Query: 207 RGEFSDFHGPPKKIIKVQKDESSTGSLAMSTRPRRVIERPPLTQQQAAQKRTCDSITPSK 266
RG+ D P ++ Q+D S+ + T E ++++ A + +S+ S+
Sbjct: 348 RGDNPD---PTTSYVEDQEDSDSSEEDSSHTLSHSKSE----SREEQADSESSESLNFSE 400
Query: 267 SSPVPVSD--TQKLKNLPFKTSGLETAKKRNSISDDDTDSEDELRMMIAKEENLQRTTQP 324
SP D + + L +S E+ + + +DD+DS+D R +E+ T
Sbjct: 401 ESPESPEDENSSSQEGLQSHSSSAESQSEESHSEEDDSDSQDSSR----SKEDSNSTESK 456
Query: 325 SINESESDPFEVVRDDFKSGVHKLHSLIGLGIKNRVSCHD 364
S +E + + + K V H+ +G ++ C D
Sbjct: 457 SSSEEDGQLKNIEIESRKLTVDAYHNK-PIGDQDDNDCQD 495
>gi|16445438 bromodomain and WD repeat domain containing 1 isoform B
[Homo sapiens]
Length = 2269
Score = 50.8 bits (120), Expect = 7e-06
Identities = 103/495 (20%), Positives = 187/495 (37%), Gaps = 57/495 (11%)
Query: 645 QKRQTTFESQDRKAVSPSSSEK-RSKNPISRPLEGKKSLSLSAKTHNIGFDKDSCHSTTK 703
Q++ +SQ K++ ++ +S+ I L G + S S++T +G K S ++
Sbjct: 1440 QRQNCKGDSQPNKSIRNLKPKRLKSQTKIIPELVGSPTQSTSSRTAYLGTHKTSAGISSG 1499
Query: 704 TEASQEERSDSSGLTSLKKSPKVSSKDTRE------IKTDFSLSISNSSDVSAKDKHAED 757
+ S S + P + E + T S S S+SS+ S + A +
Sbjct: 1500 VTSGDSSDSAESSERRKRNRPITNGSTLSESEVEDSLATSLSSSASSSSEESKESSRARE 1559
Query: 758 NEKRLAALEARQ----KAKEVQKKLVHNALANLDGHPEDKPTHIIFGSDSECETEETSTQ 813
+ R + + + Q+K +LAN G + ++ SDS+ + ET
Sbjct: 1560 SSSRSGLSRSSNLRVTRTRAAQRKTGPVSLANGCGRKATRKR--VYLSDSDNNSLETGEI 1617
Query: 814 EQSHPGE--EWVKESMGKTSGKLFDSSDDDESDSEDDSNRFKIKPQFEGRAGQKLMDLQS 871
++ G + +++ + K+ SD +E+ S + + P A + L +
Sbjct: 1618 LKARAGNNRKVLRKCAAVAANKIKLMSDVEENSSSESVCSGRKLPHRNASAVARKKLLHN 1677
Query: 872 HFGTDDRFRMDSRFLETDSEEEQE--EVNEKKTA-----EEEELAEEKKKALNVVQSVLQ 924
++D + S E + ++E + V+ TA E E E + L V +
Sbjct: 1678 ---SEDEQSLKSEIEEEELKDENQLLPVSSSHTAQSNVDESENRDSESESDLRVARKNWH 1734
Query: 925 INLSNSTNRGSVAAKKFKDIIHYDPTKQDHATYERKRDDKPKES--KAKRKKKREEAEKL 982
N S K K + +K + + R P S K K + EEA+
Sbjct: 1735 ANGYKSHTPAPSKTKFLKIESSEEDSKSHDSDHACNRTAGPSTSVQKLKAESISEEADSE 1794
Query: 983 PEVSKEMYYNIAMDLKEIFQTTKYTSEKEEGTPWNED-----CGKEKPEEIQ-----DPA 1032
P S YN F+ TK S+ E+ +D C K + I DP
Sbjct: 1795 PGRSGGRKYNTFHKNASFFKKTKILSDSEDSESEEQDREDGKCHKMEMNPISGNLNCDPI 1854
Query: 1033 ALTSDAEQPSGFTFSFFDSDTKDIKEETYRVETVKPGKIVWQEDPRLQDSSSEEEDVTEE 1092
A++ + T D D+ D K E KP ++DS+S++ ++ +
Sbjct: 1855 AMSQCSSDHGCET----DLDSDDDKIE-------KPNNF-------MKDSASQDNGLSRK 1896
Query: 1093 TDHRN--SSPGEASL 1105
+ SS ++SL
Sbjct: 1897 ISRKRVCSSDSDSSL 1911
Score = 40.0 bits (92), Expect = 0.013
Identities = 74/342 (21%), Positives = 132/342 (38%), Gaps = 65/342 (19%)
Query: 226 DESSTGSLAMSTRPRRVIERPP---LTQQQAAQKRTCDSITPSKSSPVPVSDTQKLKNLP 282
+ES S A + R + R +T+ +AAQ++T PV +++
Sbjct: 1549 EESKESSRARESSSRSGLSRSSNLRVTRTRAAQRKT---------GPVSLANG------- 1592
Query: 283 FKTSGLETAKKRNSISDDDTDSEDELRMMIAKEEN----LQRTTQPSINESE--SDPFEV 336
G + +KR +SD D +S + ++ A+ N L++ + N+ + SD E
Sbjct: 1593 ---CGRKATRKRVYLSDSDNNSLETGEILKARAGNNRKVLRKCAAVAANKIKLMSDVEEN 1649
Query: 337 VRDDFKSGVHKLHSLIGLGIKNRVSCHDSDDD--IMRNDREYDSGDTDEIIAMKKNVAKV 394
+ KL + + H+S+D+ + E + D ++++ + +
Sbjct: 1650 SSSESVCSGRKLPHRNASAVARKKLLHNSEDEQSLKSEIEEEELKDENQLLPVSSSHTAQ 1709
Query: 395 KNSTEFSQMEKSTKKTSFKNRENCELSDHC--------IKLQKRKSNVESALSHGLK-SL 445
N E + ++ R+N + + K K +S+ E + SH +
Sbjct: 1710 SNVDESENRDSESESDLRVARKNWHANGYKSHTPAPSKTKFLKIESSEEDSKSHDSDHAC 1769
Query: 446 NRKS-PSHSSSSEDADSASELADSE----GGEEYNAMMKNCLRVNLTLADLEQLAGSDLK 500
NR + PS S A+S SE ADSE GG +YN KN T + L+ S+
Sbjct: 1770 NRTAGPSTSVQKLKAESISEEADSEPGRSGGRKYNTFHKNASFFKKT----KILSDSEDS 1825
Query: 501 VPNEDTKSDG-----------------PETTTQCKFDRGSKS 525
E + DG P +QC D G ++
Sbjct: 1826 ESEEQDREDGKCHKMEMNPISGNLNCDPIAMSQCSSDHGCET 1867
>gi|16445436 bromodomain and WD repeat domain containing 1 isoform A
[Homo sapiens]
Length = 2320
Score = 50.8 bits (120), Expect = 7e-06
Identities = 103/495 (20%), Positives = 187/495 (37%), Gaps = 57/495 (11%)
Query: 645 QKRQTTFESQDRKAVSPSSSEK-RSKNPISRPLEGKKSLSLSAKTHNIGFDKDSCHSTTK 703
Q++ +SQ K++ ++ +S+ I L G + S S++T +G K S ++
Sbjct: 1440 QRQNCKGDSQPNKSIRNLKPKRLKSQTKIIPELVGSPTQSTSSRTAYLGTHKTSAGISSG 1499
Query: 704 TEASQEERSDSSGLTSLKKSPKVSSKDTRE------IKTDFSLSISNSSDVSAKDKHAED 757
+ S S + P + E + T S S S+SS+ S + A +
Sbjct: 1500 VTSGDSSDSAESSERRKRNRPITNGSTLSESEVEDSLATSLSSSASSSSEESKESSRARE 1559
Query: 758 NEKRLAALEARQ----KAKEVQKKLVHNALANLDGHPEDKPTHIIFGSDSECETEETSTQ 813
+ R + + + Q+K +LAN G + ++ SDS+ + ET
Sbjct: 1560 SSSRSGLSRSSNLRVTRTRAAQRKTGPVSLANGCGRKATRKR--VYLSDSDNNSLETGEI 1617
Query: 814 EQSHPGE--EWVKESMGKTSGKLFDSSDDDESDSEDDSNRFKIKPQFEGRAGQKLMDLQS 871
++ G + +++ + K+ SD +E+ S + + P A + L +
Sbjct: 1618 LKARAGNNRKVLRKCAAVAANKIKLMSDVEENSSSESVCSGRKLPHRNASAVARKKLLHN 1677
Query: 872 HFGTDDRFRMDSRFLETDSEEEQE--EVNEKKTA-----EEEELAEEKKKALNVVQSVLQ 924
++D + S E + ++E + V+ TA E E E + L V +
Sbjct: 1678 ---SEDEQSLKSEIEEEELKDENQLLPVSSSHTAQSNVDESENRDSESESDLRVARKNWH 1734
Query: 925 INLSNSTNRGSVAAKKFKDIIHYDPTKQDHATYERKRDDKPKES--KAKRKKKREEAEKL 982
N S K K + +K + + R P S K K + EEA+
Sbjct: 1735 ANGYKSHTPAPSKTKFLKIESSEEDSKSHDSDHACNRTAGPSTSVQKLKAESISEEADSE 1794
Query: 983 PEVSKEMYYNIAMDLKEIFQTTKYTSEKEEGTPWNED-----CGKEKPEEIQ-----DPA 1032
P S YN F+ TK S+ E+ +D C K + I DP
Sbjct: 1795 PGRSGGRKYNTFHKNASFFKKTKILSDSEDSESEEQDREDGKCHKMEMNPISGNLNCDPI 1854
Query: 1033 ALTSDAEQPSGFTFSFFDSDTKDIKEETYRVETVKPGKIVWQEDPRLQDSSSEEEDVTEE 1092
A++ + T D D+ D K E KP ++DS+S++ ++ +
Sbjct: 1855 AMSQCSSDHGCET----DLDSDDDKIE-------KPNNF-------MKDSASQDNGLSRK 1896
Query: 1093 TDHRN--SSPGEASL 1105
+ SS ++SL
Sbjct: 1897 ISRKRVCSSDSDSSL 1911
Score = 40.0 bits (92), Expect = 0.013
Identities = 74/342 (21%), Positives = 132/342 (38%), Gaps = 65/342 (19%)
Query: 226 DESSTGSLAMSTRPRRVIERPP---LTQQQAAQKRTCDSITPSKSSPVPVSDTQKLKNLP 282
+ES S A + R + R +T+ +AAQ++T PV +++
Sbjct: 1549 EESKESSRARESSSRSGLSRSSNLRVTRTRAAQRKT---------GPVSLANG------- 1592
Query: 283 FKTSGLETAKKRNSISDDDTDSEDELRMMIAKEEN----LQRTTQPSINESE--SDPFEV 336
G + +KR +SD D +S + ++ A+ N L++ + N+ + SD E
Sbjct: 1593 ---CGRKATRKRVYLSDSDNNSLETGEILKARAGNNRKVLRKCAAVAANKIKLMSDVEEN 1649
Query: 337 VRDDFKSGVHKLHSLIGLGIKNRVSCHDSDDD--IMRNDREYDSGDTDEIIAMKKNVAKV 394
+ KL + + H+S+D+ + E + D ++++ + +
Sbjct: 1650 SSSESVCSGRKLPHRNASAVARKKLLHNSEDEQSLKSEIEEEELKDENQLLPVSSSHTAQ 1709
Query: 395 KNSTEFSQMEKSTKKTSFKNRENCELSDHC--------IKLQKRKSNVESALSHGLK-SL 445
N E + ++ R+N + + K K +S+ E + SH +
Sbjct: 1710 SNVDESENRDSESESDLRVARKNWHANGYKSHTPAPSKTKFLKIESSEEDSKSHDSDHAC 1769
Query: 446 NRKS-PSHSSSSEDADSASELADSE----GGEEYNAMMKNCLRVNLTLADLEQLAGSDLK 500
NR + PS S A+S SE ADSE GG +YN KN T + L+ S+
Sbjct: 1770 NRTAGPSTSVQKLKAESISEEADSEPGRSGGRKYNTFHKNASFFKKT----KILSDSEDS 1825
Query: 501 VPNEDTKSDG-----------------PETTTQCKFDRGSKS 525
E + DG P +QC D G ++
Sbjct: 1826 ESEEQDREDGKCHKMEMNPISGNLNCDPIAMSQCSSDHGCET 1867
>gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1
[Homo sapiens]
Length = 651
Score = 48.9 bits (115), Expect = 3e-05
Identities = 86/393 (21%), Positives = 158/393 (40%), Gaps = 35/393 (8%)
Query: 648 QTTFESQDRKAVSPSSSEKRSKNPISRPLEGKKSLSLSAKTHNIGFDKDSCHSTTKTEAS 707
+T ESQ+ K VS + S+K K+ KK+ + T N KD S T +
Sbjct: 180 ETNPESQNSKTVSKNCSQKDKKD----SKNSKKTNTEFLHTKN-NPKKDLKRSKTSNDPI 234
Query: 708 QEERSDSSGLTSLKKSPKVSSKDTREIKTDFSL---SISNSSDVSAK-----DKHAEDNE 759
E S++S ++ V D I D L S +NS + S K K + N
Sbjct: 235 SEICSENS--LNVDFLMLVGQSDDESINFDAWLRNYSQNNSKNYSLKYTKYTKKDTKKNA 292
Query: 760 KRLAALEAR--QKAKEVQKKLVHNALANLDGHPEDKPTHIIFGSDSECETEETSTQEQSH 817
K+ + E+ + AK+ KK+ N + K T +D+E + ++
Sbjct: 293 KKSSDAESEDSKDAKKDSKKVKKNVKKDDKKKDVKKDTE---STDAESGDSKDERKDTKK 349
Query: 818 PGEEWVKESMGKTSGKLFDSSDDDESDSEDDSNRFKIKPQFEGRAGQKLMDLQSHFGTDD 877
++ K+ K + K +S+D + D++D N + + +K + F TD
Sbjct: 350 DKKKLKKDDKKKDTKKYPESTDTESGDAKDARNDSRNLKKASKNDDKKKDAKKITFSTDS 409
Query: 878 RFRMDSRFLETDSEEEQEEVNEKKTAEEEELAEEKKKALNVVQSV-LQINLSNSTNRGSV 936
++S+ E +++E +KK ++ + KK N +S + +G
Sbjct: 410 ESELESK------ESQKDEKKDKKDSK----TDNKKSVKNDEESTDADSEPKGDSKKGKK 459
Query: 937 AAKKFKDIIHYDPTKQD----HATYERKRDDKPKESKAKRKKKREEAEKLPEVSKEMYYN 992
KK K D K+D + E + D + K+ K K+K+ + + + +++ +
Sbjct: 460 DEKKGKKDSKKDDKKKDAKKNAESTEMESDLELKKDKKHSKEKKGSKKDIKKDARKDTES 519
Query: 993 IAMDLKEIFQTTKYTSEKEEGTPWNEDCGKEKP 1025
+ E +T TS K +G+ + KP
Sbjct: 520 TDAEFDESSKTGFKTSTKIKGSDTESEESLYKP 552
Score = 42.4 bits (98), Expect = 0.003
Identities = 70/342 (20%), Positives = 131/342 (38%), Gaps = 33/342 (9%)
Query: 580 YEKESMKKSLKDSVASNNKDQNSMKHEDPSI---ISMEDGSPYVNGSLGEVTPCQHAKKA 636
Y K+ KK+ K S + ++D K + + + +D V + +
Sbjct: 283 YTKKDTKKNAKKSSDAESEDSKDAKKDSKKVKKNVKKDDKKKDVK---------KDTEST 333
Query: 637 NGPNYIQPQKRQTTFESQDRKAVSPSSSEKRSKN-PISRPLEGKKSLSLSAKTHNIGFDK 695
+ + +R+ T +D+K + +K +K P S E + + N+ K
Sbjct: 334 DAESGDSKDERKDT--KKDKKKLKKDDKKKDTKKYPESTDTESGDAKDARNDSRNL--KK 389
Query: 696 DSCHSTTKTEASQEERS-DSSGLTSLKKSPKVSSKDTREIKTDFSLSISNSSDVSAKD-- 752
S + K +A + S DS K+S K KD ++ KTD S+ N + + D
Sbjct: 390 ASKNDDKKKDAKKITFSTDSESELESKESQKDEKKDKKDSKTDNKKSVKNDEESTDADSE 449
Query: 753 ------KHAEDNEKRLAALEARQKAKEVQKKLVHNAL-ANLDGHPEDKPTHIIFGSDSEC 805
K +D +K + K K+ +K + ++L+ + K + GS +
Sbjct: 450 PKGDSKKGKKDEKKGKKDSKKDDKKKDAKKNAESTEMESDLELKKDKKHSKEKKGSKKDI 509
Query: 806 ETEETSTQEQSHPGEEWVKESMGKTSGKLFDSSDDDESDSEDDSNRFKIKPQFEGRAGQK 865
+ + E + + ++ KTS K+ S + E + KI A K
Sbjct: 510 KKDARKDTESTDAEFDESSKTGFKTSTKIKGSDTESEESLYKPGAKKKIDESDGTSANSK 569
Query: 866 LMDLQSHFGTDDRFRMDSRFLETDSEEEQEEVNEKKTAEEEE 907
+ L+S G FRM S+ +T E+ E+ + + E
Sbjct: 570 MEGLESKRG----FRMSSK--KTTFNEKGEKASTGRVPPSRE 605
Score = 38.1 bits (87), Expect = 0.049
Identities = 88/493 (17%), Positives = 183/493 (37%), Gaps = 80/493 (16%)
Query: 652 ESQDRKAVSP--SSSEKRSKNPISRPLEGKKSLSLSAKTHNIGFDKDSCHSTTKTEASQE 709
+S+D K +P S+K+ + + P E K+ + K N DK S+ + E S++
Sbjct: 117 KSKDEKGGTPLKKDSKKKGGSYATNP-ESKQIVEEKTKRQNEA-DKTPLKSSHENEQSKK 174
Query: 710 ERSDSSGLTSLKKSPKVSSKDTREIKTDFSLSISNSSDVSAKDKHAEDNEKRLAA--LEA 767
+S S + S VS + S KDK N K+ L
Sbjct: 175 SKSSSETNPESQNSKTVSK------------------NCSQKDKKDSKNSKKTNTEFLHT 216
Query: 768 RQKAKEVQK--KLVHNALANLDGHPEDKPTHIIFGSDSECET----------EETSTQEQ 815
+ K+ K K ++ ++ + ++ S+ E+ + +++
Sbjct: 217 KNNPKKDLKRSKTSNDPISEICSENSLNVDFLMLVGQSDDESINFDAWLRNYSQNNSKNY 276
Query: 816 SHPGEEWVKESMGKTSGKLFDSSDDDESDSEDDSNRFKIKPQFEGRAGQKLMDLQS---- 871
S ++ K+ K + K D+ +D D++ DS + K + + + D +S
Sbjct: 277 SLKYTKYTKKDTKKNAKKSSDAESEDSKDAKKDSKKVKKNVKKDDKKKDVKKDTESTDAE 336
Query: 872 ----------------HFGTDDRFRMDSRFLE-TDSEE------EQEEVNEKKTAEEEEL 908
DD+ + ++ E TD+E + N KK ++ ++
Sbjct: 337 SGDSKDERKDTKKDKKKLKKDDKKKDTKKYPESTDTESGDAKDARNDSRNLKKASKNDDK 396
Query: 909 AEEKKKALNVVQSVLQINLSNSTNRGSVAAKKFKDIIHYDPTKQDHATYERKRDDKPKES 968
++ KK S ++ S + + KK + K D + + + K
Sbjct: 397 KKDAKKITFSTDSESELE-SKESQKDEKKDKKDSKTDNKKSVKNDEESTDADSEPKGDSK 455
Query: 969 KAKRKKKREEAEKLPEVSKEMYYNIAMDLKEIFQTTKYTSEKEEGTPWNEDCGKEKPEEI 1028
K K+ +K+ + + + K+ D K+ ++T+ S+ E ++ KEK
Sbjct: 456 KGKKDEKKGKKDSKKDDKKK-------DAKKNAESTEMESDLE--LKKDKKHSKEKKGSK 506
Query: 1029 QDPAALTSDAEQPSGFTFSFFDSDTKDIKEETYRVETVKPGKIVWQEDPRLQDSSSEEED 1088
+D + DA + + T + FD +K ++ T G E+ + + ++ D
Sbjct: 507 KD---IKKDARKDTESTDAEFDESSK----TGFKTSTKIKGSDTESEESLYKPGAKKKID 559
Query: 1089 VTEETDHRNSSPG 1101
++ T + G
Sbjct: 560 ESDGTSANSKMEG 572
Score = 36.6 bits (83), Expect = 0.14
Identities = 104/546 (19%), Positives = 189/546 (34%), Gaps = 108/546 (19%)
Query: 256 KRTCDSITPSKSSPVPVSDTQKLKNLPFKT---SGLETAKKRNSISDDDTDSEDELRMMI 312
K+ S + S V + K +N KT S E + + S S +T+ E + +
Sbjct: 132 KKKGGSYATNPESKQIVEEKTKRQNEADKTPLKSSHENEQSKKSKSSSETNPESQNSKTV 191
Query: 313 AKE---------ENLQRTTQPSINESESDPFEVVRDDFKSG-VHKLHSLIGLGIKNRVSC 362
+K +N ++T ++ + ++ R + + ++ S L + +
Sbjct: 192 SKNCSQKDKKDSKNSKKTNTEFLHTKNNPKKDLKRSKTSNDPISEICSENSLNVDFLMLV 251
Query: 363 HDSDDDIMRNDREYDSGDTDEIIAMKKNVAKVKNSTEFSQMEKSTKKTSFKNRENCELSD 422
SDD+ + D A +N ++ + + K TKK + KN
Sbjct: 252 GQSDDESINFD------------AWLRNYSQNNSKNYSLKYTKYTKKDTKKNA------- 292
Query: 423 HCIKLQKRKSNVESALSHGLKSLNRKSPSH---SSSSEDADSASELADSEGGEEYNAMMK 479
K+ S+ ES S K ++K + +D +E D+E G+ +
Sbjct: 293 ------KKSSDAESEDSKDAKKDSKKVKKNVKKDDKKKDVKKDTESTDAESGDSKDERKD 346
Query: 480 NCLRVNLTLADLEQLAGSDLKVPNEDTKSDGPETTTQCKFDRGSKSPKTPTGLRRGRQCI 539
T D ++L D K +DTK T T+ + +++
Sbjct: 347 -------TKKDKKKLKKDDKK---KDTKKYPESTDTESGDAKDARNDSR----------- 385
Query: 540 RPAEIVASLLEGEENTCGKQKPKENNLKPKFQAFKGVGCLYEKESMKKSLKDSVASNNKD 599
+L + +N K+ K+ ++ L KES K KD S +
Sbjct: 386 -------NLKKASKNDDKKKDAKKITFSTDSESE-----LESKESQKDEKKDKKDSKTDN 433
Query: 600 QNSMKHEDPSIISMEDGSPYVNGSLGEVTPCQHAKKANGPNYIQPQKRQTTFESQDRKAV 659
+ S+K+++ S + D P + G+ + KK + +K+ ++ +
Sbjct: 434 KKSVKNDEES--TDADSEPKGDSKKGK----KDEKKGKKDSKKDDKKKDAKKNAESTEME 487
Query: 660 SPSSSEKRSKNPISRPLEGKKSLSLSAKTHNIGFDKDSCHSTTKTEASQEERSDSSGLTS 719
S +K K+ S+ +G K KD K S + D S T
Sbjct: 488 SDLELKKDKKH--SKEKKGSK--------------KDIKKDARKDTESTDAEFDESSKTG 531
Query: 720 LKKSPKVSSKDTRE----IKTDFSLSISNSSDVSAKDKHAEDNEKRLAALEARQKAKEVQ 775
K S K+ DT K I S SA K + LE+++ +
Sbjct: 532 FKTSTKIKGSDTESEESLYKPGAKKKIDESDGTSANSK--------MEGLESKRGFRMSS 583
Query: 776 KKLVHN 781
KK N
Sbjct: 584 KKTTFN 589
Score = 35.8 bits (81), Expect = 0.24
Identities = 68/351 (19%), Positives = 135/351 (38%), Gaps = 41/351 (11%)
Query: 368 DIMRNDREYDSGDTDEIIAMKKNVAKVKNSTEFSQMEKSTKK-TSFKNRENCELSDHCIK 426
D +N ++ ++++ KK+ KVK + + +K KK T + E+ + D
Sbjct: 287 DTKKNAKKSSDAESEDSKDAKKDSKKVKKNVKKDDKKKDVKKDTESTDAESGDSKD---- 342
Query: 427 LQKRKSNVESALSHGLKSLNRKSPSHSSSSEDADSASELADSEGGEEYNAMMKNCLRVNL 486
+RK + ++K +D E D+E G+ +A +N R NL
Sbjct: 343 --ERKDTKK----------DKKKLKKDDKKKDTKKYPESTDTESGDAKDA--RNDSR-NL 387
Query: 487 TLADLEQLAGSDLKVPNEDTKSDGPETTTQCKFDRGSKSPKTPTGLRRGRQCIRPAEIVA 546
A N+D K D + T + +S ++ ++ ++ + +
Sbjct: 388 KKAS-----------KNDDKKKDAKKITFSTDSESELESKESQKDEKKDKKDSK-TDNKK 435
Query: 547 SLLEGEENTCGKQKPKENNLKPKFQAFKGVGCLYEKESMKKSLKDSVASNNKDQNSMKHE 606
S+ EE+T +PK ++ K K KG K+ KK K A N + M+
Sbjct: 436 SVKNDEESTDADSEPKGDSKKGKKDEKKG------KKDSKKDDKKKDAKKNAESTEME-S 488
Query: 607 DPSIISMEDGSPYVNGSLGEVTPCQHAKKANGPNYIQPQKRQTTFESQDRKAVSPSSSEK 666
D + + S GS ++ K + + +T F++ + S + SE+
Sbjct: 489 DLELKKDKKHSKEKKGSKKDIKK-DARKDTESTDAEFDESSKTGFKTSTKIKGSDTESEE 547
Query: 667 RSKNP-ISRPLEGKKSLSLSAKTHNIGFDKDSCHSTTKTEASQEERSDSSG 716
P + ++ S ++K + + S+ KT +++ S+G
Sbjct: 548 SLYKPGAKKKIDESDGTSANSKMEGLESKRGFRMSSKKTTFNEKGEKASTG 598
>gi|145580615 KRI1 homolog [Homo sapiens]
Length = 709
Score = 48.1 bits (113), Expect = 5e-05
Identities = 82/356 (23%), Positives = 139/356 (39%), Gaps = 56/356 (15%)
Query: 708 QEERSDSSGLTSLKKS-PKVSSKDTREIKTDFSLSISNSSDVSAKDKHAEDNEKRLAALE 766
Q+ER L+ LKK P++ KD F ++SSD S +D A + +K++ +
Sbjct: 67 QQERDFYKTLSLLKKKDPRIYQKDAT-----FYNRTASSSD-SEEDPEALEKQKKVRPMY 120
Query: 767 ARQKAKEVQKKLVHNALANLDGHPEDKPTHIIFGSDSECETEETSTQEQSHPGEEWVKES 826
+ ++V ++ A +D D G S +ETS+Q ++ +KES
Sbjct: 121 LKDYERKV---ILEKAGKYVDEENSD-------GETSNHRLQETSSQSYVEEQKQ-LKES 169
Query: 827 MGKTSGKLFDSSDDDESDSEDDSNRFK-------------------IKPQFEGRAGQKLM 867
+ S+D++ E S+ + +K Q E R L
Sbjct: 170 FRA----FVEDSEDEDGAGEGGSSLLQKRAKTRQEKAQEEADYIEWLKGQKEIRNPDSLK 225
Query: 868 DLQ--SHFGTDDRFRMDSRFLETDSEEEQEEVNEKKTAEEEELAEEKKKALNVVQSVLQI 925
+L + D RFL ++ E E++ +EEE+ EE+ V +Q+
Sbjct: 226 ELTHLKEYWNDPELDEGERFLRDYILNKRYEEEEEEEEDEEEMEEEE----GVHGPPVQL 281
Query: 926 NLSNSTNRGSVAAKKFKDIIHY------DPTKQDHATYERKRDDKPKESKAKRKKKREEA 979
+ +S++ G + KK +D +P TY R + +RK+KREE
Sbjct: 282 AVDDSSDEGELFLKKQEDFEQKYNFRFEEPDSASVKTYPRSIASSVRRKDERRKEKREET 341
Query: 980 EKLPEVSKEMYYNIAMDLKEIFQTTKYTS-EKEEGTPWNEDCGKEKP--EEIQDPA 1032
+ + K LK + + EK NE G E+ E+ DPA
Sbjct: 342 RERKKREKAKKQEELKQLKNLKRKEILAKLEKLRKVTGNEMLGLEEGDLEDDFDPA 397
Score = 33.9 bits (76), Expect = 0.93
Identities = 40/196 (20%), Positives = 80/196 (40%), Gaps = 23/196 (11%)
Query: 836 DSSDDDESDSEDDSNRFKIKPQFEGRAGQKLMDLQSHFGTDDR-FRMDSRFL-----ETD 889
DSS D S+S+ R + PQ E + L L+ D R ++ D+ F +D
Sbjct: 46 DSSSDSSSESDSSDERVEFDPQQERDFYKTLSLLKK---KDPRIYQKDATFYNRTASSSD 102
Query: 890 SEEEQEEVNEKKTAEEEELAEEKKKAL--NVVQSVLQINLSNSTNRGSVAAKKFKDII-H 946
SEE+ E + ++K L + ++K + + V + N T+ + + +
Sbjct: 103 SEEDPEALEKQKKVRPMYLKDYERKVILEKAGKYVDEENSDGETSNHRLQETSSQSYVEE 162
Query: 947 YDPTKQDHATYERKRDDK-----------PKESKAKRKKKREEAEKLPEVSKEMYYNIAM 995
K+ + +D+ K +K +++K +EEA+ + + +
Sbjct: 163 QKQLKESFRAFVEDSEDEDGAGEGGSSLLQKRAKTRQEKAQEEADYIEWLKGQKEIRNPD 222
Query: 996 DLKEIFQTTKYTSEKE 1011
LKE+ +Y ++ E
Sbjct: 223 SLKELTHLKEYWNDPE 238
>gi|148596949 nucleolar and coiled-body phosphoprotein 1 [Homo
sapiens]
Length = 699
Score = 47.4 bits (111), Expect = 8e-05
Identities = 96/506 (18%), Positives = 171/506 (33%), Gaps = 80/506 (15%)
Query: 264 PSKSSPVPVSDTQKLKNLPFKTSGLETAKKRNSISDDDTDSEDELRMMIAKEENLQRTTQ 323
P+K + VP +++ P K + + + S DD D ED+ K++ +Q+ +
Sbjct: 101 PAKKAAVPA---KRVGLPPGKAAAKASESSSSEESSDDDDEEDQ------KKQPVQKGVK 151
Query: 324 PSINESESDPFEVVRDDFKSGVHKLHSLIGLGIKNRVSCHDSDDDIMRNDREYDS----- 378
P +++ P + D S S+D+ +N + +
Sbjct: 152 PQAKAAKAPPKKAKSSDSDSD------------------SSSEDEPPKNQKPKITPVTVK 193
Query: 379 GDTDEIIAMKKNVAKVKNSTEFSQMEKSTKKTSFKNRENCELSDHCIKLQKRKSNVESAL 438
T + K+ N S S+ +S + E + + K +K V A
Sbjct: 194 AQTKAPPKPARAAPKIANGKAASSSSSSSSSSSSDDSEEEKAAATPKKTVPKKQVVAKAP 253
Query: 439 SHGLKSLNRKSPSHSSSSEDADSASELADSEGGEEYNAMMKNCLRVNLTLADLEQLAGSD 498
+ RKS SSSED+ S E EE MKN
Sbjct: 254 VKAATTPTRKS----SSSEDSSSDEE-------EEQKKPMKN------------------ 284
Query: 499 LKVPNEDTKSDGPETTTQCKFDRGSKSPKTPTGLRRGRQCIRPAEIVASLLEGEENTCGK 558
GP ++ + PK G + ++ + + V S E+++
Sbjct: 285 ---------KPGPYSSVP---PPSAPPPKKSLGTQPPKKAVEKQQPVES---SEDSSDES 329
Query: 559 QKPKENNLKPKFQAFKGVGCLYEKESMK--KSLKDSVASNNKDQNSMKHEDPSIISMEDG 616
E KP +A + K +S DS S++ + + +
Sbjct: 330 DSSSEEEKKPPTKAVVSKATTKPPPAKKAAESSSDSSDSDSSEDDEAPSKPAGTTKNSSN 389
Query: 617 SPYVNGSLGEVTPCQHAKKANGPNYIQPQKRQTTFESQDRKAVSPSSSEKRSKNPISRPL 676
P V V P K+ G ++ + S++ + S K+
Sbjct: 390 KPAVTTKSPAVKPAAAPKQPVGGGQKLLTRKADSSSSEEESSSSEEEKTKKMVATTKPKA 449
Query: 677 EGKKSLSLSAKTHNIGFDKDSCHSTTKTEASQEERSDSSGLTSLKKSPKVSSKDTREIKT 736
K +LSL AK G S S + + +EE++ S + KK KV+
Sbjct: 450 TAKAALSLPAKQAPQGSRDSSSDSDSSSSEEEEEKTSKSAVK--KKPQKVAGGAAPSKPA 507
Query: 737 DFSLSISNSSDVSAKDKHAEDNEKRL 762
+ SS+ S+ D +E+ E++L
Sbjct: 508 SAKKGKAESSNSSSSDDSSEEEEEKL 533
Score = 46.6 bits (109), Expect = 1e-04
Identities = 122/629 (19%), Positives = 215/629 (34%), Gaps = 99/629 (15%)
Query: 372 NDREYDSGDTDEIIAMKKNVAKVKNSTEFSQMEKSTKKTSFKNRENCELSDHCIKLQKRK 431
+D E S + +E+ A V K+ K S ++ + E SD + ++K
Sbjct: 85 SDSEDSSEEEEEVQGPPAKKAAVPAKRVGLPPGKAAAKAS-ESSSSEESSDDDDEEDQKK 143
Query: 432 SNVESALSHGLKSLNRKSPSHSSSSEDADSASELADSEGGEEYNAMMKNCLRVNLTLADL 491
V+ + K+ K+P + S D+DS S D + + ++
Sbjct: 144 QPVQKGVKPQAKAA--KAPPKKAKSSDSDSDSSSEDEPPKNQKPKITPVTVKAQTKAPPK 201
Query: 492 EQLAGSDLKVPNEDTKSDGPETTTQCKFDRGSKSPKTPTGLRRGRQCIRPAEIVASLLEG 551
A + + S +++ K+ TP +Q + A + A+
Sbjct: 202 PARAAPKIANGKAASSSSSSSSSSSSDDSEEEKAAATPKKTVPKKQVVAKAPVKAATTPT 261
Query: 552 EENTCGKQKPKENNLKPKFQAFKGVGCLYEKESMKKSLKDSVASNNKDQNSMKHEDPSII 611
+++ + + E+E KK +K NK PS
Sbjct: 262 RKSSSSEDSSSD-----------------EEEEQKKPMK------NKPGPYSSVPPPS-- 296
Query: 612 SMEDGSPYVNGSLGEVTPCQHAKKANGPNYIQPQKRQTTFESQDRKAVSPSSSEKRSKNP 671
+P SLG P KKA +K+Q S+D S SSSE+ K P
Sbjct: 297 -----APPPKKSLGTQPP----KKA-------VEKQQPVESSEDSSDESDSSSEEEKKPP 340
Query: 672 I--------SRPLEGKKSLSLSAKTHNIGFDKDSCHSTTKTEASQEERSDSSGLTSLKKS 723
++P KK+ S+ + + +D + +K + + S+ +T+ +
Sbjct: 341 TKAVVSKATTKPPPAKKAAESSSDSSDSDSSEDD-EAPSKPAGTTKNSSNKPAVTTKSPA 399
Query: 724 PKVSSKDTREIKTDFSLSISNSSDVSAKDKHAEDNEKRLAALEARQKAKEVQKKLVHNAL 783
K ++ + + L + S++++ + E++ + A K K K +
Sbjct: 400 VKPAAAPKQPVGGGQKLLTRKADSSSSEEESSSSEEEKTKKMVATTKPKATAKAALSLPA 459
Query: 784 ANLDGHPEDKPTHIIFGSDSECETEETST-----QEQSHPGEEWVKESMGKTSGKLFDS- 837
D + S SE E E+TS + Q G + GK S
Sbjct: 460 KQAPQGSRDSSSDSD-SSSSEEEEEKTSKSAVKKKPQKVAGGAAPSKPASAKKGKAESSN 518
Query: 838 --SDDDESDSEDDSNRFKIKPQFEGRAGQKLMDLQSHFGTDDRFRMDSRFLETDSEEEQE 895
S DD S+ E++ + K P+ + L + G
Sbjct: 519 SSSSDDSSEEEEEKLKGKGSPRPQAPKANGTSALTAQNG--------------------- 557
Query: 896 EVNEKKTAEEEELAEEKKKALNVVQSVLQINLSNSTNRGSVA----AKKFKDIIHYDPTK 951
K +EEEE EEKKKA VV + A AKK K
Sbjct: 558 --KAAKNSEEEE--EEKKKAAVVVSKSGSLKKRKQNEAAKEAETPQAKKIK--------L 605
Query: 952 QDHATYERKRDDKPKESKAKRKKKREEAE 980
Q T+ +++ + + S R+ + EE E
Sbjct: 606 QTPNTFPKRKKGEKRASSPFRRVREEEIE 634
Score = 44.3 bits (103), Expect = 7e-04
Identities = 88/485 (18%), Positives = 174/485 (35%), Gaps = 85/485 (17%)
Query: 635 KANGPNYIQPQKRQTTFESQDRKAVSPSSSEKRSKNPISRPLEGKKSLSLSAKTHNIGFD 694
+ANGP + +K+ ++ +S+D SSE+ + ++G + + +G
Sbjct: 69 QANGPVAKKAKKKASSSDSED-------SSEEEEE------VQGPPAKKAAVPAKRVGLP 115
Query: 695 KDSCHSTTKTEASQEERSDSSGLTSLKKSP---------KVSSKDTREIKTDFSLSISNS 745
+ +S EE SD KK P K + ++ K S +
Sbjct: 116 PGKAAAKASESSSSEESSDDDDEEDQKKQPVQKGVKPQAKAAKAPPKKAK-----SSDSD 170
Query: 746 SDVSAKDKHAEDNEKRLAALEARQKAKEVQKKL-VHNALANLDGHPEDKPTHIIFGSDSE 804
SD S++D+ ++ + ++ + + + K K +AN + SD
Sbjct: 171 SDSSSEDEPPKNQKPKITPVTVKAQTKAPPKPARAAPKIANGKAASSSSSSSSSSSSDDS 230
Query: 805 CETEETSTQEQSHPGEEWVKESMGK---TSGKLFDSSDDDESDSEDDSNR-FKIKP---- 856
E + +T +++ P ++ V ++ K T + SS+D SD E++ + K KP
Sbjct: 231 EEEKAAATPKKTVPKKQVVAKAPVKAATTPTRKSSSSEDSSSDEEEEQKKPMKNKPGPYS 290
Query: 857 ----------------QFEGRAGQKLMDLQSHFGTDDRFRMDSRFLETDSEEEQEEVNEK 900
Q +A +K ++S + D ++ SEEE++ +
Sbjct: 291 SVPPPSAPPPKKSLGTQPPKKAVEKQQPVESSEDSSDES-------DSSSEEEKKPPTKA 343
Query: 901 KTAEEEELAEEKKKALNVVQSVLQINLS--------------NSTNRGSVAAKK---FKD 943
++ KKA + S NS+N+ +V K
Sbjct: 344 VVSKATTKPPPAKKAAESSSDSSDSDSSEDDEAPSKPAGTTKNSSNKPAVTTKSPAVKPA 403
Query: 944 IIHYDPTKQDHATYERKRDDKPKESKAKRKKKREEAEKLPEVSKEMYYNIAMDL------ 997
P RK D E ++ ++ + + + + A+ L
Sbjct: 404 AAPKQPVGGGQKLLTRKADSSSSEEESSSSEEEKTKKMVATTKPKATAKAALSLPAKQAP 463
Query: 998 ---KEIFQTTKYTSEKEEGTPWNEDCGKEKPEEIQDPAALTSDAEQPSGFTFSFFDSDTK 1054
++ + +S +EE ++ K+KP+++ AA + A G S S +
Sbjct: 464 QGSRDSSSDSDSSSSEEEEEKTSKSAVKKKPQKVAGGAAPSKPASAKKGKAESSNSSSSD 523
Query: 1055 DIKEE 1059
D EE
Sbjct: 524 DSSEE 528
Score = 37.0 bits (84), Expect = 0.11
Identities = 115/558 (20%), Positives = 203/558 (36%), Gaps = 109/558 (19%)
Query: 220 IIKVQKDESSTGSLAMSTRPRRVIERPPLTQQQAAQKRT-----------CDSITPSKSS 268
+ K K ++S+ S+ ++ PP + KR +S + +SS
Sbjct: 74 VAKKAKKKASSSDSEDSSEEEEEVQGPPAKKAAVPAKRVGLPPGKAAAKASESSSSEESS 133
Query: 269 PVPVSDTQKLKNLP------FKTSGLETAKKRNSISDDDTDSEDELRMMIAKEENLQRTT 322
+ QK + + K + K ++S SD D+ SEDE + + T
Sbjct: 134 DDDDEEDQKKQPVQKGVKPQAKAAKAPPKKAKSSDSDSDSSSEDE-----PPKNQKPKIT 188
Query: 323 QPSINESESDPFEVVRDDFKSGVHKLHSLIGLGIKNRVSCHDSDDDIMRNDREYDSGDTD 382
++ P + R K K S + S SDD ++ E +
Sbjct: 189 PVTVKAQTKAPPKPARAAPKIANGKAAS----SSSSSSSSSSSDD----SEEEKAAATPK 240
Query: 383 EIIAMKKNVAK--VKNSTEFSQMEKSTKKTSFKNRENCELSDHCIKLQKRKSNVESAL-- 438
+ + K+ VAK VK +T T+K+S + + + K K K S++
Sbjct: 241 KTVPKKQVVAKAPVKAAT------TPTRKSSSSEDSSSDEEEEQKKPMKNKPGPYSSVPP 294
Query: 439 ---SHGLKSLNRKSPSHSSSS----EDADSASELADSEGGEEYNAMMKNCLRVNLTLADL 491
KSL + P + E ++ +S+ +DS EE K + T
Sbjct: 295 PSAPPPKKSLGTQPPKKAVEKQQPVESSEDSSDESDSSSEEEKKPPTKAVVSKATTKPPP 354
Query: 492 EQLA------GSDLKVPNED-----------TKSDGPETTTQCKFDRGSKSPKTPTGLRR 534
+ A SD +D S+ P TT+ + + +PK P G
Sbjct: 355 AKKAAESSSDSSDSDSSEDDEAPSKPAGTTKNSSNKPAVTTKSPAVKPAAAPKQPVG--- 411
Query: 535 GRQCIRPAEIVASLLEGEENTCGKQKPKE--NNLKPKFQAFKGVGCLYEK--ESMKKSLK 590
G Q + + +S E E ++ ++K K+ KPK A + ++ + + S
Sbjct: 412 GGQKLLTRKADSSSSEEESSSSEEEKTKKMVATTKPKATAKAALSLPAKQAPQGSRDSSS 471
Query: 591 DSVASNNKDQNSM----------------------------KHEDPSIISMEDGSPYVNG 622
DS +S+++++ K E + S +D S
Sbjct: 472 DSDSSSSEEEEEKTSKSAVKKKPQKVAGGAAPSKPASAKKGKAESSNSSSSDDSSEEEEE 531
Query: 623 SL-GEVTPCQHAKKANGPNYIQPQ-----KRQTTFESQDRKA---VSPSSS-EKRSKNPI 672
L G+ +P A KANG + + Q K E + +KA VS S S +KR +N
Sbjct: 532 KLKGKGSPRPQAPKANGTSALTAQNGKAAKNSEEEEEEKKKAAVVVSKSGSLKKRKQNEA 591
Query: 673 SRPLEGKKSLSLSAKTHN 690
++ E ++ + +T N
Sbjct: 592 AKEAETPQAKKIKLQTPN 609
Score = 31.2 bits (69), Expect = 6.0
Identities = 65/316 (20%), Positives = 107/316 (33%), Gaps = 54/316 (17%)
Query: 803 SECETEETSTQEQSHPGEEWVKESM---------GKTSGKLFDSSDDDESDSEDDSNRFK 853
S ++E++S +E+ G K ++ GK + K +SS +ES +DD K
Sbjct: 83 SSSDSEDSSEEEEEVQGPPAKKAAVPAKRVGLPPGKAAAKASESSSSEESSDDDDEEDQK 142
Query: 854 IKPQFEGRAGQKLMDLQSHFGTDDRFRMDSRFLETDSEEEQEEVNEKK------TAEEEE 907
+P QK + Q+ + S ++DS E E +K T + +
Sbjct: 143 KQPV------QKGVKPQAKAAKAPPKKAKSSDSDSDSSSEDEPPKNQKPKITPVTVKAQT 196
Query: 908 LAEEKK----------KALNVVQSVLQINLSNSTNRGSVAAKKFKDIIHYDPTKQDHATY 957
A K KA + S + S+ + AA K + P KQ A
Sbjct: 197 KAPPKPARAAPKIANGKAASSSSSSSSSSSSDDSEEEKAAATPKKTV----PKKQVVAKA 252
Query: 958 ERKRDDKP---KESKAKRKKKREEAEKLPEVSKEMYYNIAMDLKEIFQTTKYTSEKEEGT 1014
K P S EE +K P +K Y+ +
Sbjct: 253 PVKAATTPTRKSSSSEDSSSDEEEEQKKPMKNKPGPYS--------------SVPPPSAP 298
Query: 1015 PWNEDCGKEKPEEIQDPAALTSDAEQPSGFTFSFFDSDTKDIKEETYRVETVK--PGKIV 1072
P + G + P++ + +E S + S + + K + T K P K
Sbjct: 299 PPKKSLGTQPPKKAVEKQQPVESSEDSSDESDSSSEEEKKPPTKAVVSKATTKPPPAKKA 358
Query: 1073 WQEDPRLQDSSSEEED 1088
+ DS S E+D
Sbjct: 359 AESSSDSSDSDSSEDD 374
>gi|62244004 modulator of estrogen induced transcription isoform b
[Homo sapiens]
Length = 1016
Score = 47.4 bits (111), Expect = 8e-05
Identities = 26/105 (24%), Positives = 56/105 (53%), Gaps = 8/105 (7%)
Query: 7 TKRLYVGGLSQDISEADLQNQFSRFGEVSDVEIITRKDDQGNPQKVFAYINISVAEADLK 66
TK ++V GLS + ADL+N F ++G+V +++T G K + + +S + ++
Sbjct: 365 TKNIWVSGLSSNTKAADLKNLFGKYGKVLSAKVVTNARSPG--AKCYGIVTMS-SSTEVS 421
Query: 67 KCMSVLNKTKWKGGTLQIQLAKESFLHRLAQEREAAKAKKEESTT 111
+C++ L++T+ G + ++ K ++E K E+S++
Sbjct: 422 RCIAHLHRTELHGQLISVEKVKGD-----PSKKEMKKENDEKSSS 461
Score = 38.9 bits (89), Expect = 0.029
Identities = 72/358 (20%), Positives = 127/358 (35%), Gaps = 56/358 (15%)
Query: 717 LTSLKKSPKVSSKDTREIKTDFSLSISNSSDVSAKDK-HAEDNEKRLAALEARQKAKEVQ 775
++ LK++ + D I+ S N K K H D A++E K+ +
Sbjct: 49 ISRLKQAIEEEGGDPDNIELTVSTDTPNKKPTKGKGKKHEADELSGDASVEDDAFIKDCE 108
Query: 776 KKLVHNALANLDGHPEDKPTHIIFGSDSECETEETSTQEQSHP-GEEWVKESMGKTSGKL 834
L N + H +D G+D ++EE E+ + +E + K + +L
Sbjct: 109 -------LENQEAHEQD-------GNDELKDSEEFGENEEENVHSKELLSAEENKRAHEL 154
Query: 835 FDSSDDDESDSEDDSNRFKIKPQFEGRAGQKLMDLQSHFGTDDRFRMDSRFLETDSEEEQ 894
++ ++ + ED ++ ++++ G DD F L EE+
Sbjct: 155 IEAEGIEDIEKEDIESQ----------------EIEAQEGEDDTF------LTAQDGEEE 192
Query: 895 EEVNEKKTAEEEELAEEKKKALNVVQSVLQINLSNSTNRGSVAAKKFK-----------D 943
E E AE + A E+ +A V+ N+S + F
Sbjct: 193 ENEKEGSLAEADHTAHEEMEAHTTVKEAEDDNISVTIQAEDAITLDFDGDDLLETGKNVK 252
Query: 944 IIHYDPTK----QDHATYERKRDDKPKESKAKRKK-KREEAEKLPEVSKEMYYNIAMDLK 998
I + +K QD +++ K E A K K+E+ K V KE +
Sbjct: 253 ITDSEASKPKDGQDAIAQSPEKESKDYEMNANHKDGKKEDCVKGDPVEKEA--RESSKKA 310
Query: 999 EIFQTTKYTSEKEEGTPWNEDCGKEKPEEIQDPAALTSDAEQPSGFTFSFFDSDTKDI 1056
E K T +K + K +E +D + D + + T S TK+I
Sbjct: 311 ESGDKEKDTLKKGPSSTGASGQAKSSSKESKDSKTSSKDDKGSTSSTSGSSGSSTKNI 368
Score = 34.7 bits (78), Expect = 0.54
Identities = 96/510 (18%), Positives = 188/510 (36%), Gaps = 72/510 (14%)
Query: 289 ETAKKRNSISDDDTDSEDELRMMIAKEENLQRTTQPSINESESDPFEVVRDDFKSGVHKL 348
E +K S+++ D + +E+ +E +I ++ + DD
Sbjct: 192 EENEKEGSLAEADHTAHEEMEAHTTVKEAEDDNISVTIQAEDAITLDFDGDDLLE----- 246
Query: 349 HSLIGLGIK---NRVSCHDSDDDIMRNDREYDSGDTDEIIAMKKNVAK---VKNSTEFSQ 402
G +K + S D + E +S D E+ A K+ K VK +
Sbjct: 247 ---TGKNVKITDSEASKPKDGQDAIAQSPEKESKDY-EMNANHKDGKKEDCVKGDPVEKE 302
Query: 403 MEKSTKKTSFKNRENCELSDHCIKLQKRKSNVESALSHGLKSLNRKSP-SHSSSSEDADS 461
+S+KK ++E L +K + S KS +++S S +SS +D S
Sbjct: 303 ARESSKKAESGDKEKDTL---------KKGPSSTGASGQAKSSSKESKDSKTSSKDDKGS 353
Query: 462 ASELADSEGGEEYNAMMKNCLRVNLTLADLEQLAGSDLKVPNEDTKSDGPETTTQCKFDR 521
S + S G N + L N ADL+ L G KV + ++ +C
Sbjct: 354 TSSTSGSSGSSTKNIWVSG-LSSNTKAADLKNLFGKYGKVLSAKVVTNARSPGAKC---Y 409
Query: 522 GSKSPKTPTGLRRGRQCIRPAEIVASLLEGEE---NTCGKQKPKENNLKPKFQAFKGVGC 578
G + + T + R + E+ L+ E+ + K+ KEN+
Sbjct: 410 GIVTMSSSTEVSRCIAHLHRTELHGQLISVEKVKGDPSKKEMKKEND------------- 456
Query: 579 LYEKESMKKS--LKDSVASNNKDQNSMKHEDPSIISMEDGSPYVNGSLGEVTPCQHAKKA 636
EK S + S K++ ++K Q S+K E+ + E + KK
Sbjct: 457 --EKSSSRSSGDKKNTSDRSSKTQASVKKEEKR-----------SSEKSEKKESKDTKKI 503
Query: 637 NGPNYIQPQKRQTTFESQDRKAVSPSSSEKR--SKNPISRPLEGKKSLSLSAKTHNIGFD 694
G + +K Q +++ S +KR SK+P + + + ++
Sbjct: 504 EG----KDEKNDNGASGQTSESIKKSEEKKRISSKSPGHMVILDQTKGDHCRPSRRGRYE 559
Query: 695 KDSCHSTTKTEASQEERSDSS-GLTSLKKSPKVSSKDTREIKTDF-----SLSISNSSDV 748
K S K AS +++ D + K+ + RE F ++ + ++
Sbjct: 560 KIHGRSKEKERASLDKKRDKDYRRKEILPFEKMKEQRLREHLVRFERLRRAMELRRRREI 619
Query: 749 SAKDKHAEDNEKRLAALEARQKAKEVQKKL 778
+ +++ + + + E R++ + +++L
Sbjct: 620 AERERRERERIRIIREREERERLQRERERL 649
>gi|63176611 modulator of estrogen induced transcription isoform a
[Homo sapiens]
Length = 1034
Score = 47.4 bits (111), Expect = 8e-05
Identities = 26/105 (24%), Positives = 56/105 (53%), Gaps = 8/105 (7%)
Query: 7 TKRLYVGGLSQDISEADLQNQFSRFGEVSDVEIITRKDDQGNPQKVFAYINISVAEADLK 66
TK ++V GLS + ADL+N F ++G+V +++T G K + + +S + ++
Sbjct: 383 TKNIWVSGLSSNTKAADLKNLFGKYGKVLSAKVVTNARSPG--AKCYGIVTMS-SSTEVS 439
Query: 67 KCMSVLNKTKWKGGTLQIQLAKESFLHRLAQEREAAKAKKEESTT 111
+C++ L++T+ G + ++ K ++E K E+S++
Sbjct: 440 RCIAHLHRTELHGQLISVEKVKGD-----PSKKEMKKENDEKSSS 479
Score = 37.7 bits (86), Expect = 0.064
Identities = 84/431 (19%), Positives = 159/431 (36%), Gaps = 97/431 (22%)
Query: 717 LTSLKKSPKVSSKDTREIKTDFSLSISNSSDVSAKDK-HAEDNEKRLAALEARQKAKEVQ 775
++ LK++ + D I+ S N K K H D A++E K+ +
Sbjct: 49 ISRLKQAIEEEGGDPDNIELTVSTDTPNKKPTKGKGKKHEADELSGDASVEDDAFIKDCE 108
Query: 776 KKLVHNALANLDGHPEDKPTHIIFGSDSECETEETSTQEQSHP-GEEWVKESMGKTSGKL 834
L N + H +D G+D ++EE E+ + +E + K + +L
Sbjct: 109 -------LENQEAHEQD-------GNDELKDSEEFGENEEENVHSKELLSAEENKRAHEL 154
Query: 835 FDSSDDDESDSEDDSNRFKIKPQFEGRAGQKLMDLQSHFGTDDRFRMDSRFLETDSEEEQ 894
++ ++ + ED ++ ++++ G DD F +++ +
Sbjct: 155 IEAEGIEDIEKEDIESQ----------------EIEAQEGEDDTF--------LTAQDGE 190
Query: 895 EEVNEKKTAEEEELAEEKKKALNVVQSVLQINLSNSTNRGSVAAKKFKDIIHYDPTKQDH 954
EE NEK A + +E K L + GS+A + DH
Sbjct: 191 EEENEKDIAGSGDGTQEVSKPL--------------PSEGSLA-------------EADH 223
Query: 955 ATYERKRDDKPKESKAKRKKKREEAEKLP-EVSKEMYYNIAMDLKEIFQTTKYTSEKEEG 1013
+E E +A K E + + + E + D ++ +T K
Sbjct: 224 TAHE--------EMEAHTTVKEAEDDNISVTIQAEDAITLDFDGDDLLETGKNVKIT--- 272
Query: 1014 TPWNEDCGKEKPEEIQDPAALTSDAEQPSGFTFSFFDSDTKDIKEETYRVETVK--PGKI 1071
D KP++ QD A + + E +++ KD K+E + VK P +
Sbjct: 273 -----DSEASKPKDGQDAIAQSPEKESKD----YEMNANHKDGKKE----DCVKGDPVEK 319
Query: 1072 VWQEDPRLQDSSSEEEDVTEETDHRNSSPGEASLLEKETTRFFFFSKNDERLQGSDLFWR 1131
+E + +S +E+D ++ + G+A KE+ SK+D +GS
Sbjct: 320 EARESSKKAESGDKEKDTLKKGPSSTGASGQAKSSSKESKDSKTSSKDD---KGSTSSTS 376
Query: 1132 GVGSNMSRNSW 1142
G + ++N W
Sbjct: 377 GSSGSSTKNIW 387
Score = 33.9 bits (76), Expect = 0.93
Identities = 76/399 (19%), Positives = 150/399 (37%), Gaps = 57/399 (14%)
Query: 394 VKNSTEFSQMEKSTKKTSFKNRENCELSDHCIKLQKRKSNVESALSHGLKSLNRKSP-SH 452
VK + +S+KK ++E L +K + S KS +++S S
Sbjct: 312 VKGDPVEKEARESSKKAESGDKEKDTL---------KKGPSSTGASGQAKSSSKESKDSK 362
Query: 453 SSSSEDADSASELADSEGGEEYNAMMKNCLRVNLTLADLEQLAGSDLKVPNEDTKSDGPE 512
+SS +D S S + S G N + L N ADL+ L G KV + ++
Sbjct: 363 TSSKDDKGSTSSTSGSSGSSTKNIWVSG-LSSNTKAADLKNLFGKYGKVLSAKVVTNARS 421
Query: 513 TTTQCKFDRGSKSPKTPTGLRRGRQCIRPAEIVASLLEGEE---NTCGKQKPKENNLKPK 569
+C G + + T + R + E+ L+ E+ + K+ KEN+
Sbjct: 422 PGAKC---YGIVTMSSSTEVSRCIAHLHRTELHGQLISVEKVKGDPSKKEMKKEND---- 474
Query: 570 FQAFKGVGCLYEKESMKKS--LKDSVASNNKDQNSMKHEDPSIISMEDGSPYVNGSLGEV 627
EK S + S K++ ++K Q S+K E+ + E
Sbjct: 475 -----------EKSSSRSSGDKKNTSDRSSKTQASVKKEEKR-----------SSEKSEK 512
Query: 628 TPCQHAKKANGPNYIQPQKRQTTFESQDRKAVSPSSSEKR--SKNPISRPLEGKKSLSLS 685
+ KK G + +K Q +++ S +KR SK+P + +
Sbjct: 513 KESKDTKKIEG----KDEKNDNGASGQTSESIKKSEEKKRISSKSPGHMVILDQTKGDHC 568
Query: 686 AKTHNIGFDKDSCHSTTKTEASQEERSDSS-GLTSLKKSPKVSSKDTREIKTDF-----S 739
+ ++K S K AS +++ D + K+ + RE F +
Sbjct: 569 RPSRRGRYEKIHGRSKEKERASLDKKRDKDYRRKEILPFEKMKEQRLREHLVRFERLRRA 628
Query: 740 LSISNSSDVSAKDKHAEDNEKRLAALEARQKAKEVQKKL 778
+ + +++ +++ + + + E R++ + +++L
Sbjct: 629 MELRRRREIAERERRERERIRIIREREERERLQRERERL 667
>gi|41872583 Rho-associated, coiled-coil containing protein kinase 2
[Homo sapiens]
Length = 1388
Score = 47.0 bits (110), Expect = 1e-04
Identities = 129/718 (17%), Positives = 289/718 (40%), Gaps = 78/718 (10%)
Query: 316 ENLQRTTQPSINESESDPFEVVRDDFKSGVHKLHSLIGLGIKNRVSCHDSDDDIMR--ND 373
ENL + PS E++S + +++ + K + + N + + + + N
Sbjct: 418 ENLLLSDSPSCRETDS--IQSRKNEESQEIQKKLYTLEEHLSNEMQAKEELEQKCKSVNT 475
Query: 374 R-EYDSGDTDEIIAMKKNVAKVKNSTEFSQMEKSTKKTSFKNRENCELSDHCIKLQKRKS 432
R E + + +E I ++K+V + Q+E+ KN E +DH ++
Sbjct: 476 RLEKTAKELEEEITLRKSV-----ESALRQLEREKALLQHKNAEYQRKADHEADKKRNLE 530
Query: 433 NVESALSHGLKSLNRKSPSHSSSSEDADSASELADSEGGEEYNAMMK----NCLRVNLTL 488
N ++L L+ L +++ + S+E + D E NA+++ R+ T
Sbjct: 531 NDVNSLKDQLEDLKKRNQNSQISTEKVNQLQRQLD-----ETNALLRTESDTAARLRKTQ 585
Query: 489 AD----LEQLAGSDLKVPNEDTKSDGPETTTQCKFDRGSKSPKTPTGLRRGRQCIRPAEI 544
A+ ++QL ++ + +++ + T + K ++ + ++ R R +EI
Sbjct: 586 AESSKQIQQLESNNRDLQDKNCLLE----TAKLKLEKEFINLQSALESER-RDRTHGSEI 640
Query: 545 VASLLEGEENTCGKQKPKENNLKPKFQAFKGVGCLYEKESMKKSLKDSVASNNKDQNSMK 604
+ L + CG ++ +N G L + E K+ L++ K++++M+
Sbjct: 641 INDL---QGRICGLEEDLKN----------GKILLAKVELEKRQLQERFTDLEKEKSNME 687
Query: 605 HEDPSIISMEDGSPYVNGSLGEVTPCQHAKKANGPNYIQPQKRQTTFESQDRKAVSPSSS 664
+ + + S + + T + A K I+ K + + ++K + +
Sbjct: 688 IDMTYQLKVIQQSLEQEEAEHKATKARLADKNKIYESIEEAKSE-AMKEMEKKLLEERTL 746
Query: 665 EKRSKNPISRPLEGKKSLSL--------SAKTHNIGFDKDSCHS-----TTKTEASQEER 711
+++ +N + LE +K SL K + + KD + T K E ++R
Sbjct: 747 KQKVENLL---LEAEKRCSLLDCDLKQSQQKINELLKQKDVLNEDVRNLTLKIEQETQKR 803
Query: 712 ----SDSSGLTSLKKSPKVSSKDTREIKTDFSLSISNSSDVSAK-DKHAEDNEKRLAALE 766
+D T + K+S K ++ N +A+ K +D + ++ L+
Sbjct: 804 CLTQNDLKMQTQQVNTLKMSEKQLKQENNHLMEMKMNLEKQNAELRKERQDADGQMKELQ 863
Query: 767 ARQKAKEVQKKLVHNALANLDGHPEDKPTHIIFGSDSECETEETSTQEQSHPGEEWVKES 826
+ +A++ L + L E+K G + + + +E + S + ++ +
Sbjct: 864 DQLEAEQYFSTLYKTQVRELKEECEEKTK---LGKELQQKKQELQDERDSLAAQ--LEIT 918
Query: 827 MGKTSGKLFDSSDDDESDSEDDSNRFKIKPQFEGRAGQKLMDLQSHFGTDDRFRMDSRFL 886
+ K + S +E S+ + + + + + + +L T +R L
Sbjct: 919 LTKADSEQLARSIAEEQYSDLEKEKIMKELEIKEMMARHKQELTEKDATIASLEETNRTL 978
Query: 887 ETD---SEEEQEEVNEKKTAEEEELAEEKKKALNVVQSVLQINLSNSTNR--GSVAAKKF 941
+D E+EE+N K +E+L+ K + ++ Q T R + A K
Sbjct: 979 TSDVANLANEKEELNNKLKDVQEQLSRLKDEEISAAAIKAQFEKQLLTERTLKTQAVNKL 1038
Query: 942 KDIIH-YDPTKQDHATYERKRDDKPK----ESKAKRKKKREEAEKLPEVSKEMYYNIA 994
+I++ +P K+ + T R+++ + + E K++R+K ++ K + EM IA
Sbjct: 1039 AEIMNRKEPVKRGNDTDVRRKEKENRKLHMELKSEREKLTQQMIKYQKELNEMQAQIA 1096
>gi|8922328 RNA binding motif protein 22 [Homo sapiens]
Length = 420
Score = 47.0 bits (110), Expect = 1e-04
Identities = 33/132 (25%), Positives = 55/132 (41%), Gaps = 16/132 (12%)
Query: 10 LYVGGLSQDISEADLQNQFSRFGEVSDVEIITRKDDQGNPQKVFAYINISVAEADLKKCM 69
LYVGGL I+E DL+N F +FGE+ + ++ R+ A+I + +A
Sbjct: 234 LYVGGLGDTITETDLRNHFYQFGEIRTITVVQRQQ--------CAFIQFATRQAAEVAAE 285
Query: 70 SVLNKTKWKGGTLQIQLAKESFLHRLAQEREAAKAKKEESTTGNANLLEKTGGVDFHMKA 129
NK G L ++ + + K K+++ TT + LE G+ +
Sbjct: 286 KSFNKLIVNGRRLNVKWGR--------SQAARGKEKEKDGTTDSGIKLEPVPGLPGALPP 337
Query: 130 VPGTEVPGHKNW 141
P E N+
Sbjct: 338 PPAAEEEASANY 349
>gi|24415404 MDN1, midasin homolog [Homo sapiens]
Length = 5596
Score = 47.0 bits (110), Expect = 1e-04
Identities = 127/662 (19%), Positives = 252/662 (38%), Gaps = 94/662 (14%)
Query: 375 EYDSGDTDEIIAMKKNVAKVKNSTEFSQMEKSTKKTSFKNRENCELSDHCIKLQKRKSNV 434
+Y+ G E MK ++ N Q+E + +K K++E+ + KS++
Sbjct: 4674 DYEGGGIGEGEGMKDVSDQIGNE---EQVEDTFQKGQEKDKEDPD----------SKSDI 4720
Query: 435 ESALSHGLKSLNRKSPSHSSSSEDADSASELADSEGGEEYNAMMKNCLRVNLTLADL--E 492
+ + S + H E+ + E +DSEGG+ + K+ +N AD E
Sbjct: 4721 KGEDNAIEMSEDFDGKMHDGELEEQEEDDEKSDSEGGD----LDKHMGDLNGEEADKLDE 4776
Query: 493 QLAGSDLKVPNEDTKSDGPETTTQCKFDRGSKSPKTPTGLRRGRQCIRPAEIVASLLEGE 552
+L G D + +E+ + +K+ +T G+ +E+VA +
Sbjct: 4777 RLWGDDDEEEDEE--------------EEDNKTEETGPGMDE-----EDSELVAKDDNLD 4817
Query: 553 ENTCGKQKPKENNLKPKFQAFKGVGCLYEKESMKKSLKDSVASNNKDQ---NSMKHEDPS 609
K K +++ + K +A G E + ++ + N D N K +P
Sbjct: 4818 SGNSNKDKSQQDKKEEKEEAEADDGGQGEDKINEQIDERDYDENEVDPYHGNQEKVPEPE 4877
Query: 610 IISMED----GSPYVNGSLGEVTPCQHAKKANGPNYIQPQKRQTTFESQDRKAVSPSSSE 665
+ + D S NG GE T + ++ N P I+ + + E+++R +E
Sbjct: 4878 ALDLPDDLNLDSEDKNG--GEDTDNEEGEEEN-PLEIKEKPEEAGHEAEERGETETDQNE 4934
Query: 666 KRS-KNPISRP-----LEGKKSLSL-------SAKTHNIGFDKDSCHSTTKTEASQEERS 712
+S + P P EG++ + A H ++ S + + +E
Sbjct: 4935 SQSPQEPEEGPSEDDKAEGEEEMDTGADDQDGDAAQHPEEHSEEQQQSVEEKDKEADEEG 4994
Query: 713 DSSGLTSLKKSP-KVSSKDTREIKTDFSLSISNSSDVSAKDKHAEDNEKRLAALEARQKA 771
+G P + ++ + + ++ S E+ + A A
Sbjct: 4995 GENGPADQGFQPQEEEEREDSDTEEQVPEALERKEHASCGQTGVENMQNTQAMELAGAAP 5054
Query: 772 KEVQKKLVHNALANLDGHPEDKPTHIIFGSDSECETEETSTQEQSHPGEEWVKESMGKTS 831
++ Q K H + A E ++ I S+ T + + + PG+ + SMG +
Sbjct: 5055 EKEQGKEEHGSGAADANQAEGHESNFIAQLASQKHTRKNTQSFKRKPGQADNERSMGDHN 5114
Query: 832 GKLFDSSDDDESDSEDDSNRFKIKPQFEGRAGQKLMDLQSHF--GTDDRFRMDSRFLETD 889
++ ++DS + P + +A + D H G+D D++ +
Sbjct: 5115 ERVHKRLRTVDTDSHAEQG-----PAQQPQAQVEDADAFEHIKQGSD---AYDAQTYDVA 5166
Query: 890 SEEEQEEVNEK-KTAEEEEL--------AEEKKKALNVVQSVLQINLSNSTNRGSVAAKK 940
S+E+Q+ + K EEEE+ +E+ KA +V Q + S +T
Sbjct: 5167 SKEQQQSAKDSGKDQEEEEIEDTLMDTEEQEEFKAADVEQLKPEEIKSGTTAP------- 5219
Query: 941 FKDIIHYDPTKQDHATYERKRDDKPKESKAKRKKKREEAEKLPEVSKEMYYNIAMDLKEI 1000
+ +D + + T + + D P+ KA ++ + E+ E+ E + + MD I
Sbjct: 5220 ----LGFDEMEVEIQTVKTEEDQDPRTDKAHKETENEKPERSRESTIHTAHQFLMD--TI 5273
Query: 1001 FQ 1002
FQ
Sbjct: 5274 FQ 5275
Score = 42.7 bits (99), Expect = 0.002
Identities = 69/303 (22%), Positives = 114/303 (37%), Gaps = 78/303 (25%)
Query: 820 EEWVKESMGKTSGKLFDSSD-DDESDSEDDSNRFKIKPQFEGRAGQKLM----------- 867
EE V+++ K K D D D +SD + + N ++ F+G+ +
Sbjct: 4696 EEQVEDTFQKGQEK--DKEDPDSKSDIKGEDNAIEMSEDFDGKMHDGELEEQEEDDEKSD 4753
Query: 868 ----DLQSHFGT---DDRFRMDSRFLETDSEEEQEEVNEKKTAEEEELAEEKKKALNVVQ 920
DL H G ++ ++D R D EEE EE + KT E +E+ L
Sbjct: 4754 SEGGDLDKHMGDLNGEEADKLDERLWGDDDEEEDEEEEDNKTEETGPGMDEEDSELVAKD 4813
Query: 921 SVLQINLSNSTNRGSVAAKKFKDIIHYDPTKQDHATYERKRDDKPKESKAKRKKKREEAE 980
L SN D ++QD +K+++EEAE
Sbjct: 4814 DNLDSGNSNK-----------------DKSQQD------------------KKEEKEEAE 4838
Query: 981 KLPEVSKEMYYNIAMDLKEIFQTTKYTSEKEEGTPWNEDCGK-EKPEEIQDPAALTSDAE 1039
E N +D ++ ++ E P++ + K +PE + P L D+E
Sbjct: 4839 ADDGGQGEDKINEQIDERDY--------DENEVDPYHGNQEKVPEPEALDLPDDLNLDSE 4890
Query: 1040 QPSGFTFSFFDSDTKDIKEETYRVETVKPGKIVWQEDPRLQDSSSEEEDVTEETDHRNSS 1099
+G D+D ++ +EE P +I +E P +EE TE + + S
Sbjct: 4891 DKNGGE----DTDNEEGEEE-------NPLEI--KEKPEEAGHEAEERGETETDQNESQS 4937
Query: 1100 PGE 1102
P E
Sbjct: 4938 PQE 4940
Score = 33.5 bits (75), Expect = 1.2
Identities = 78/388 (20%), Positives = 148/388 (38%), Gaps = 77/388 (19%)
Query: 744 NSSDVSAKD---KHAEDNEKRLAALEARQKAKEVQKKLVHNA-----LANLDGHPEDKPT 795
+ SD+ +D + +ED + ++ E ++ ++ +K + +L+G DK
Sbjct: 4716 SKSDIKGEDNAIEMSEDFDGKMHDGELEEQEEDDEKSDSEGGDLDKHMGDLNGEEADKLD 4775
Query: 796 HIIFGSDSE--CETEETSTQEQSHPG-EEWVKESMGKTSGKLFDSSDDDESDSEDDSNRF 852
++G D E E EE + E++ PG +E E + K +S+ D+S + +
Sbjct: 4776 ERLWGDDDEEEDEEEEDNKTEETGPGMDEEDSELVAKDDNLDSGNSNKDKSQQDKKEEKE 4835
Query: 853 KIKPQFEGRAGQKLMDLQSHFGTDDRFRMDSRFLETDSEEEQEEVNEKKTAEEEELAEEK 912
+ + G+ K+ + ++D R + ++E + N++K E E
Sbjct: 4836 EAEADDGGQGEDKINE-----------QIDERDYD-ENEVDPYHGNQEKVPEPE------ 4877
Query: 913 KKALNVVQSVLQINLSNSTNRGSVAAKKFKDIIHYDPTKQDHATYERKRDDKPKESKAKR 972
AL++ +NL + G + E ++ P E K K
Sbjct: 4878 --ALDLPD---DLNLDSEDKNGG-----------------EDTDNEEGEEENPLEIKEKP 4915
Query: 973 KKKREEAEKLPEVSKEMYYNIAMDLKEIFQTTKYTSEKEEGTPWNEDCGKEKPEEIQDPA 1032
++ EAE+ E + ++ E EEG P +D K + EE D
Sbjct: 4916 EEAGHEAEERGETETDQ------------NESQSPQEPEEG-PSEDD--KAEGEEEMDTG 4960
Query: 1033 ALTSDA------EQPSGFTFSFFDSDTKDIKEETYRVETVKPGKIVWQEDPRLQDSSSEE 1086
A D E+ S + K+ EE G QE+ +DS +EE
Sbjct: 4961 ADDQDGDAAQHPEEHSEEQQQSVEEKDKEADEEGGENGPADQG-FQPQEEEEREDSDTEE 5019
Query: 1087 E--DVTEETDHRNSSPGEASLLEKETTR 1112
+ + E +H +S G+ + + T+
Sbjct: 5020 QVPEALERKEH--ASCGQTGVENMQNTQ 5045
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.307 0.125 0.346
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 45,929,538
Number of Sequences: 37866
Number of extensions: 2259001
Number of successful extensions: 16918
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 134
Number of HSP's successfully gapped in prelim test: 676
Number of HSP's that attempted gapping in prelim test: 12398
Number of HSP's gapped (non-prelim): 3437
length of query: 1167
length of database: 18,247,518
effective HSP length: 113
effective length of query: 1054
effective length of database: 13,968,660
effective search space: 14722967640
effective search space used: 14722967640
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.