Search of human proteins with 45593136

Search of human proteins with 45593136

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|45593136 LISCH protein isoform 3 [Homo sapiens]
         (581 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|45593136 LISCH protein isoform 3 [Homo sapiens]                   1200   0.0  
gi|45505163 LISCH protein isoform 1 [Homo sapiens]                   1176   0.0  
gi|45545424 LISCH protein isoform 2 [Homo sapiens]                    709   0.0  
gi|40786420 immunoglobulin-like domain containing receptor 2 [Ho...   204   2e-52
gi|28557777 immunoglobulin-like domain containing receptor 1 [Ho...   112   7e-25
gi|224548936 hypothetical protein LOC100170229 [Homo sapiens]          59   2e-08
gi|150418009 transforming, acidic coiled-coil containing protein...    54   3e-07
gi|5031561 transmembrane glycoprotein A33 precursor [Homo sapiens]     51   3e-06
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]        49   1e-05
gi|153251865 hypothetical protein LOC84226 [Homo sapiens]              49   2e-05
gi|4503509 eukaryotic translation initiation factor 3, subunit 1...    48   3e-05
gi|29568103 U1 small nuclear ribonucleoprotein 70 kDa [Homo sapi...    47   5e-05
gi|65301122 MARVEL domain containing 3 isoform 1 [Homo sapiens]        47   6e-05
gi|65293358 MARVEL domain containing 3 isoform 2 [Homo sapiens]        47   6e-05
gi|50083281 KIAA1853 protein [Homo sapiens]                            43   7e-04
gi|71044479 death inducer-obliterator 1 isoform c [Homo sapiens]       43   0.001
gi|154354981 regulating synaptic membrane exocytosis 2 isoform b...    43   0.001
gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens]         43   0.001
gi|14670268 RD RNA-binding protein [Homo sapiens]                      42   0.001
gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo s...    42   0.001
gi|20127499 arginine/serine-rich splicing factor 6 [Homo sapiens]      42   0.002
gi|50053795 eukaryotic translation initiation factor 4B [Homo sa...    41   0.003
gi|154354983 regulating synaptic membrane exocytosis 2 isoform a...    41   0.003
gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ...    41   0.003
gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [...    41   0.003
gi|186700623 Rab-like GTP-binding protein 1 isoform 1 [Homo sapi...    40   0.005
gi|42518065 tight junction protein 2 (zona occludens 2) isoform ...    40   0.005
gi|42518070 tight junction protein 2 (zona occludens 2) isoform ...    40   0.005
gi|32699028 V-set and immunoglobulin domain containing 1 [Homo s...    40   0.006
gi|38146113 arginine/serine-rich coiled-coil 2 isoform b [Homo s...    40   0.008

>gi|45593136 LISCH protein isoform 3 [Homo sapiens]
          Length = 581

 Score = 1200 bits (3105), Expect = 0.0
 Identities = 581/581 (100%), Positives = 581/581 (100%)

Query: 1   MQQDGLGVGTRNGSGKGRSVHPSWPWCAPRPLRYFGRDARARRAQTAAMALLAGGLSRGL 60
           MQQDGLGVGTRNGSGKGRSVHPSWPWCAPRPLRYFGRDARARRAQTAAMALLAGGLSRGL
Sbjct: 1   MQQDGLGVGTRNGSGKGRSVHPSWPWCAPRPLRYFGRDARARRAQTAAMALLAGGLSRGL 60

Query: 61  GSHPAAAGRDAVVFVWLLLSTWCTAPARAIQVTVSNPYHVVILFQPVTLPCTYQMTSTPT 120
           GSHPAAAGRDAVVFVWLLLSTWCTAPARAIQVTVSNPYHVVILFQPVTLPCTYQMTSTPT
Sbjct: 61  GSHPAAAGRDAVVFVWLLLSTWCTAPARAIQVTVSNPYHVVILFQPVTLPCTYQMTSTPT 120

Query: 121 QPIVIWKYKSFCRDRIADAFSPASVDNQLNAQLAAGNPGYNPYVECQDSVRTVRVVATKQ 180
           QPIVIWKYKSFCRDRIADAFSPASVDNQLNAQLAAGNPGYNPYVECQDSVRTVRVVATKQ
Sbjct: 121 QPIVIWKYKSFCRDRIADAFSPASVDNQLNAQLAAGNPGYNPYVECQDSVRTVRVVATKQ 180

Query: 181 GNAVTLGDYYQGRRITITGNADLTFDQTAWGDSGVYYCSVVSAQDLQGNNEAYAELIVLV 240
           GNAVTLGDYYQGRRITITGNADLTFDQTAWGDSGVYYCSVVSAQDLQGNNEAYAELIVLV
Sbjct: 181 GNAVTLGDYYQGRRITITGNADLTFDQTAWGDSGVYYCSVVSAQDLQGNNEAYAELIVLV 240

Query: 241 YAAGKAATSGVPSIYAPSTYAHLSPAKTPPPPAMIPMGPAYNGYPGGYPGDVDRSSSAGG 300
           YAAGKAATSGVPSIYAPSTYAHLSPAKTPPPPAMIPMGPAYNGYPGGYPGDVDRSSSAGG
Sbjct: 241 YAAGKAATSGVPSIYAPSTYAHLSPAKTPPPPAMIPMGPAYNGYPGGYPGDVDRSSSAGG 300

Query: 301 QGSYVPLLRDTDSSVASEVRSGYRIQASQQDDSMRVLYYMEKELANFDPSRPGPPSGRVE 360
           QGSYVPLLRDTDSSVASEVRSGYRIQASQQDDSMRVLYYMEKELANFDPSRPGPPSGRVE
Sbjct: 301 QGSYVPLLRDTDSSVASEVRSGYRIQASQQDDSMRVLYYMEKELANFDPSRPGPPSGRVE 360

Query: 361 RAMSEVTSLHEDDWRSRPSRGPALTPIRDEEWGGHSPRSPRGWDQEPAREQAGGGWRARR 420
           RAMSEVTSLHEDDWRSRPSRGPALTPIRDEEWGGHSPRSPRGWDQEPAREQAGGGWRARR
Sbjct: 361 RAMSEVTSLHEDDWRSRPSRGPALTPIRDEEWGGHSPRSPRGWDQEPAREQAGGGWRARR 420

Query: 421 PRARSVDALDDLTPPSTAESGSRSPTSNGGRSRAYMPPRSRSRDDLYDQDDSRDFPRSRD 480
           PRARSVDALDDLTPPSTAESGSRSPTSNGGRSRAYMPPRSRSRDDLYDQDDSRDFPRSRD
Sbjct: 421 PRARSVDALDDLTPPSTAESGSRSPTSNGGRSRAYMPPRSRSRDDLYDQDDSRDFPRSRD 480

Query: 481 PHYDDFRSRERPPADPRSHHHRTRDPRDNGSRSGDLPYDGRLLEEAVRKKGSEERRRPHK 540
           PHYDDFRSRERPPADPRSHHHRTRDPRDNGSRSGDLPYDGRLLEEAVRKKGSEERRRPHK
Sbjct: 481 PHYDDFRSRERPPADPRSHHHRTRDPRDNGSRSGDLPYDGRLLEEAVRKKGSEERRRPHK 540

Query: 541 EEEEEAYYPPAPPPYSETDSQASRERRLKKNLALSRESLVV 581
           EEEEEAYYPPAPPPYSETDSQASRERRLKKNLALSRESLVV
Sbjct: 541 EEEEEAYYPPAPPPYSETDSQASRERRLKKNLALSRESLVV 581


>gi|45505163 LISCH protein isoform 1 [Homo sapiens]
          Length = 630

 Score = 1176 bits (3042), Expect = 0.0
 Identities = 580/630 (92%), Positives = 581/630 (92%), Gaps = 49/630 (7%)

Query: 1   MQQDGLGVGTRNGSGKGRSVHPSWPWCAPRPLRYFGRDARARRAQTAAMALLAGGLSRGL 60
           MQQDGLGVGTRNGSGKGRSVHPSWPWCAPRPLRYFGRDARARRAQTAAMALLAGGLSRGL
Sbjct: 1   MQQDGLGVGTRNGSGKGRSVHPSWPWCAPRPLRYFGRDARARRAQTAAMALLAGGLSRGL 60

Query: 61  GSHPAAAGRDAVVFVWLLLSTWCTAPARAIQVTVSNPYHVVILFQPVTLPCTYQMTSTPT 120
           GSHPAAAGRDAVVFVWLLLSTWCTAPARAIQVTVSNPYHVVILFQPVTLPCTYQMTSTPT
Sbjct: 61  GSHPAAAGRDAVVFVWLLLSTWCTAPARAIQVTVSNPYHVVILFQPVTLPCTYQMTSTPT 120

Query: 121 QPIVIWKYKSFCRDRIADAFSPASVDNQLNAQLAAGNPGYNPYVECQDSVRTVRVVATKQ 180
           QPIVIWKYKSFCRDRIADAFSPASVDNQLNAQLAAGNPGYNPYVECQDSVRTVRVVATKQ
Sbjct: 121 QPIVIWKYKSFCRDRIADAFSPASVDNQLNAQLAAGNPGYNPYVECQDSVRTVRVVATKQ 180

Query: 181 GNAVTLGDYYQGRRITITGNADLTFDQTAWGDSGVYYCSVVSAQDLQGNNEAYAELIVL- 239
           GNAVTLGDYYQGRRITITGNADLTFDQTAWGDSGVYYCSVVSAQDLQGNNEAYAELIVL 
Sbjct: 181 GNAVTLGDYYQGRRITITGNADLTFDQTAWGDSGVYYCSVVSAQDLQGNNEAYAELIVLD 240

Query: 240 ------------------------------------------------VYAAGKAATSGV 251
                                                           +YAAGKAATSGV
Sbjct: 241 WLFVVVVCLAAFLIFLLLGICWCQCCPHTCCCYVRCPCCPDKCCCPEALYAAGKAATSGV 300

Query: 252 PSIYAPSTYAHLSPAKTPPPPAMIPMGPAYNGYPGGYPGDVDRSSSAGGQGSYVPLLRDT 311
           PSIYAPSTYAHLSPAKTPPPPAMIPMGPAYNGYPGGYPGDVDRSSSAGGQGSYVPLLRDT
Sbjct: 301 PSIYAPSTYAHLSPAKTPPPPAMIPMGPAYNGYPGGYPGDVDRSSSAGGQGSYVPLLRDT 360

Query: 312 DSSVASEVRSGYRIQASQQDDSMRVLYYMEKELANFDPSRPGPPSGRVERAMSEVTSLHE 371
           DSSVASEVRSGYRIQASQQDDSMRVLYYMEKELANFDPSRPGPPSGRVERAMSEVTSLHE
Sbjct: 361 DSSVASEVRSGYRIQASQQDDSMRVLYYMEKELANFDPSRPGPPSGRVERAMSEVTSLHE 420

Query: 372 DDWRSRPSRGPALTPIRDEEWGGHSPRSPRGWDQEPAREQAGGGWRARRPRARSVDALDD 431
           DDWRSRPSRGPALTPIRDEEWGGHSPRSPRGWDQEPAREQAGGGWRARRPRARSVDALDD
Sbjct: 421 DDWRSRPSRGPALTPIRDEEWGGHSPRSPRGWDQEPAREQAGGGWRARRPRARSVDALDD 480

Query: 432 LTPPSTAESGSRSPTSNGGRSRAYMPPRSRSRDDLYDQDDSRDFPRSRDPHYDDFRSRER 491
           LTPPSTAESGSRSPTSNGGRSRAYMPPRSRSRDDLYDQDDSRDFPRSRDPHYDDFRSRER
Sbjct: 481 LTPPSTAESGSRSPTSNGGRSRAYMPPRSRSRDDLYDQDDSRDFPRSRDPHYDDFRSRER 540

Query: 492 PPADPRSHHHRTRDPRDNGSRSGDLPYDGRLLEEAVRKKGSEERRRPHKEEEEEAYYPPA 551
           PPADPRSHHHRTRDPRDNGSRSGDLPYDGRLLEEAVRKKGSEERRRPHKEEEEEAYYPPA
Sbjct: 541 PPADPRSHHHRTRDPRDNGSRSGDLPYDGRLLEEAVRKKGSEERRRPHKEEEEEAYYPPA 600

Query: 552 PPPYSETDSQASRERRLKKNLALSRESLVV 581
           PPPYSETDSQASRERRLKKNLALSRESLVV
Sbjct: 601 PPPYSETDSQASRERRLKKNLALSRESLVV 630


>gi|45545424 LISCH protein isoform 2 [Homo sapiens]
          Length = 649

 Score =  709 bits (1830), Expect = 0.0
 Identities = 341/342 (99%), Positives = 342/342 (100%)

Query: 240 VYAAGKAATSGVPSIYAPSTYAHLSPAKTPPPPAMIPMGPAYNGYPGGYPGDVDRSSSAG 299
           +YAAGKAATSGVPSIYAPSTYAHLSPAKTPPPPAMIPMGPAYNGYPGGYPGDVDRSSSAG
Sbjct: 308 LYAAGKAATSGVPSIYAPSTYAHLSPAKTPPPPAMIPMGPAYNGYPGGYPGDVDRSSSAG 367

Query: 300 GQGSYVPLLRDTDSSVASEVRSGYRIQASQQDDSMRVLYYMEKELANFDPSRPGPPSGRV 359
           GQGSYVPLLRDTDSSVASEVRSGYRIQASQQDDSMRVLYYMEKELANFDPSRPGPPSGRV
Sbjct: 368 GQGSYVPLLRDTDSSVASEVRSGYRIQASQQDDSMRVLYYMEKELANFDPSRPGPPSGRV 427

Query: 360 ERAMSEVTSLHEDDWRSRPSRGPALTPIRDEEWGGHSPRSPRGWDQEPAREQAGGGWRAR 419
           ERAMSEVTSLHEDDWRSRPSRGPALTPIRDEEWGGHSPRSPRGWDQEPAREQAGGGWRAR
Sbjct: 428 ERAMSEVTSLHEDDWRSRPSRGPALTPIRDEEWGGHSPRSPRGWDQEPAREQAGGGWRAR 487

Query: 420 RPRARSVDALDDLTPPSTAESGSRSPTSNGGRSRAYMPPRSRSRDDLYDQDDSRDFPRSR 479
           RPRARSVDALDDLTPPSTAESGSRSPTSNGGRSRAYMPPRSRSRDDLYDQDDSRDFPRSR
Sbjct: 488 RPRARSVDALDDLTPPSTAESGSRSPTSNGGRSRAYMPPRSRSRDDLYDQDDSRDFPRSR 547

Query: 480 DPHYDDFRSRERPPADPRSHHHRTRDPRDNGSRSGDLPYDGRLLEEAVRKKGSEERRRPH 539
           DPHYDDFRSRERPPADPRSHHHRTRDPRDNGSRSGDLPYDGRLLEEAVRKKGSEERRRPH
Sbjct: 548 DPHYDDFRSRERPPADPRSHHHRTRDPRDNGSRSGDLPYDGRLLEEAVRKKGSEERRRPH 607

Query: 540 KEEEEEAYYPPAPPPYSETDSQASRERRLKKNLALSRESLVV 581
           KEEEEEAYYPPAPPPYSETDSQASRERRLKKNLALSRESLVV
Sbjct: 608 KEEEEEAYYPPAPPPYSETDSQASRERRLKKNLALSRESLVV 649



 Score =  496 bits (1276), Expect = e-140
 Identities = 241/246 (97%), Positives = 242/246 (98%)

Query: 1   MQQDGLGVGTRNGSGKGRSVHPSWPWCAPRPLRYFGRDARARRAQTAAMALLAGGLSRGL 60
           MQQDGLGVGTRNGSGKGRSVHPSWPWCAPRPLRYFGRDARARRAQTAAMALLAGGLSRGL
Sbjct: 1   MQQDGLGVGTRNGSGKGRSVHPSWPWCAPRPLRYFGRDARARRAQTAAMALLAGGLSRGL 60

Query: 61  GSHPAAAGRDAVVFVWLLLSTWCTAPARAIQVTVSNPYHVVILFQPVTLPCTYQMTSTPT 120
           GSHPAAAGRDAVVFVWLLLSTWCTAPARAIQVTVSNPYHVVILFQPVTLPCTYQMTSTPT
Sbjct: 61  GSHPAAAGRDAVVFVWLLLSTWCTAPARAIQVTVSNPYHVVILFQPVTLPCTYQMTSTPT 120

Query: 121 QPIVIWKYKSFCRDRIADAFSPASVDNQLNAQLAAGNPGYNPYVECQDSVRTVRVVATKQ 180
           QPIVIWKYKSFCRDRIADAFSPASVDNQLNAQLAAGNPGYNPYVECQDSVRTVRVVATKQ
Sbjct: 121 QPIVIWKYKSFCRDRIADAFSPASVDNQLNAQLAAGNPGYNPYVECQDSVRTVRVVATKQ 180

Query: 181 GNAVTLGDYYQGRRITITGNADLTFDQTAWGDSGVYYCSVVSAQDLQGNNEAYAELIVLV 240
           GNAVTLGDYYQGRRITITGNADLTFDQTAWGDSGVYYCSVVSAQDLQGNNEAYAELIVL 
Sbjct: 181 GNAVTLGDYYQGRRITITGNADLTFDQTAWGDSGVYYCSVVSAQDLQGNNEAYAELIVLG 240

Query: 241 YAAGKA 246
             +G A
Sbjct: 241 RTSGVA 246


>gi|40786420 immunoglobulin-like domain containing receptor 2 [Homo
           sapiens]
          Length = 639

 Score =  204 bits (519), Expect = 2e-52
 Identities = 187/601 (31%), Positives = 263/601 (43%), Gaps = 123/601 (20%)

Query: 70  DAVVFVWLLLSTWCTAPARAIQVTVSNPYHVVILFQPVTLPCTYQMTSTPTQPIVIWKYK 129
           D V+  W+ L  W TA    +QVTV +   V +LFQP  L C +  TS+    +V WK+K
Sbjct: 2   DRVLLRWISLF-WLTAMVEGLQVTVPDKKKVAMLFQPTVLRCHFS-TSSHQPAVVQWKFK 59

Query: 130 SFCRDRIADAFSPASVDNQLNAQLAAGNPGYNPYVECQDSVRTVRVVATKQGNAVTLGDY 189
           S+C+DR+ ++   +S   Q    L+  N  ++PY++C DS RTVRVVA+KQG+ VTLGD+
Sbjct: 60  SYCQDRMGESLGMSSTRAQ---SLSKRNLEWDPYLDCLDSRRTVRVVASKQGSTVTLGDF 116

Query: 190 YQGRRITITGNADLTFDQTAWGDSGVYYCSVVSAQDLQGNNEAYAELIVLVYAAGKAATS 249
           Y+GR ITI  +ADL   +  WGDSG+YYC + +  DL+G NE   EL+VL         +
Sbjct: 117 YRGREITIVHDADLQIGKLMWGDSGLYYCIITTPDDLEGKNEDSVELLVL-------GRT 169

Query: 250 GVPSIYAPSTYAHLSP----------------------------------AKTP------ 269
           G+ +   PS    + P                                   + P      
Sbjct: 170 GLLADLLPSFAVEIMPEWVFVGLVLLGVFLFFVLVGICWCQCCPHSCCCYVRCPCCPDSC 229

Query: 270 -PPPAMIPMGPAYN-GYP---GGYPGDVD-RSSSAGGQGS--------YVPLLRDTDSSV 315
             P A+   G A   GYP    G PG     S   GG  S        + P L  +DS+ 
Sbjct: 230 CCPQALYEAGKAAKAGYPPSVSGVPGPYSIPSVPLGGAPSSGMLMDKPHPPPLAPSDSTG 289

Query: 316 AS-EVRSGYRIQASQQDDSMRVLYYMEKELANFDPSRPGPPSGRVERAMSEVTSLHEDDW 374
            S  VR GYRIQA ++ DSM+VLYY+EKELA FDP+R     GR    +SE++SLHE+D 
Sbjct: 290 GSHSVRKGYRIQADKERDSMKVLYYVEKELAQFDPAR--RMRGRYNNTISELSSLHEEDS 347

Query: 375 RSRPS----RGPALTPIRDEE-----WG---GHSPRSPRGWDQEPAREQAGGGWRARRPR 422
             R S    R        D E     W    G S  + RG       ++    +R  +PR
Sbjct: 348 NFRQSFHQMRSKQFPVSGDLESNPDYWSGVMGGSSGASRGPSAMEYNKEDRESFRHSQPR 407

Query: 423 ARS-------------VDALDDLTPPSTAESGSRSPTSNGGRSR------AYMPPRSRSR 463
           ++S               ++D+L   + A+S  + P    G S        +    SR+ 
Sbjct: 408 SKSEMLSRKNFATGVPAVSMDELA--AFADSYGQRPRRADGNSHEARGGSRFERSESRAH 465

Query: 464 DDLYDQDDSRDF----PRSRDPHYDDFR------SRERPPADPRSHHHRTRDPRDNGSRS 513
              Y  D   ++     RSR+P  D  R      +R RP  D  +H  R        +  
Sbjct: 466 SGFYQDDSLEEYYGQRSRSREPLTDADRGWAFSPARRRPAED--AHLPRLVSRTPGTAPK 523

Query: 514 GDLPYDGRLLEEAVRKKGSE--------ERRRPHKEEEEEAYYPPAPP-PYSETDSQASR 564
            D  Y G   E   R +G+          +R         +YY  +PP  Y    SQ  +
Sbjct: 524 YDHSYLGSARERQARPEGASRGGSLETPSKRSAQLGPRSASYYAWSPPGTYKAGSSQDDQ 583

Query: 565 E 565
           E
Sbjct: 584 E 584


>gi|28557777 immunoglobulin-like domain containing receptor 1 [Homo
           sapiens]
          Length = 502

 Score =  112 bits (281), Expect = 7e-25
 Identities = 62/165 (37%), Positives = 91/165 (55%), Gaps = 9/165 (5%)

Query: 76  WLLLSTWCTAPARAIQVTVSNPYHVVILFQPVTLPCTYQMTSTPTQPIVIWKYKSFCRDR 135
           WLLL TW  A   ++ VTV +    V LF  + L C Y  ++     +V W++KSFC+D 
Sbjct: 10  WLLLCTWLPAGCLSLLVTVQHTERYVTLFASIILKCDYTTSAQLQDVVVTWRFKSFCKDP 69

Query: 136 IADAFSPASVDNQLNAQLAAGNPGYNPYVECQDSVRTVRVVATKQG-NAVTLGDYYQGRR 194
           I D +S         +  AA + G +P  +C D+ R VR+VA ++G N   LG  Y+ R+
Sbjct: 70  IFDYYSA--------SYQAALSLGQDPSNDCNDNQREVRIVAQRRGQNEPVLGVDYRQRK 121

Query: 195 ITITGNADLTFDQTAWGDSGVYYCSVVSAQDLQGNNEAYAELIVL 239
           ITI   ADL  ++  W D GVYYC++ +  D  G+ +   +LIVL
Sbjct: 122 ITIQNRADLVINEVMWWDHGVYYCTIEAPGDTSGDPDKEVKLIVL 166



 Score = 47.0 bits (110), Expect = 5e-05
 Identities = 75/269 (27%), Positives = 102/269 (37%), Gaps = 30/269 (11%)

Query: 336 VLYYMEKELANFDPSRPGPP--SGRVERAMSEVTSLHEDDWRSRPSRGPALTPIRDEEWG 393
           VL Y+EKEL N + ++P PP   GR     S ++SL  +    R    P L  IRD    
Sbjct: 241 VLEYLEKELRNLNLAQPLPPDLKGRFGHPCSMLSSLGSEVVERRIIHLPPL--IRDL--- 295

Query: 394 GHSPRSPRGWDQEPAREQAGGGWRARRPRARS-----VDALDDLTPPSTAESGSRSPTSN 448
             S R+     Q+         W  R  R+          L D  P S A        S 
Sbjct: 296 SSSRRTSDSLHQQWLTPIPSRPWDLREGRSHHHYPDFHQELQDRGPKSWALERRELDPSW 355

Query: 449 GGRSRAYMPPRSRSRDDLYDQDDSRDFPRSRD----PHYDDFRSR--ERP-PADPRSHHH 501
            GR R+     + S     D+D   D P S +    P +  FRSR  ERP    PR    
Sbjct: 356 SGRHRS--SRLNGSPIHWSDRDSLSDVPSSSEARWRPSHPPFRSRCQERPRRPSPRESTQ 413

Query: 502 RTRDPRDNGSRSGDLPYDGRLLEEAVRKKGSEERRRPHKEEEEEAYYP-PAPPPYSETD- 559
           R    R + S S  LP           K+   +  R H+      ++P   PP Y   D 
Sbjct: 414 RHGRRRRHRSYSPPLPSGLSSWSSEEDKERQPQSWRAHRRGSHSPHWPEEKPPSYRSLDI 473

Query: 560 -------SQASRERRLKKNLALSRESLVV 581
                   + S ERR +K+ + S  S+V+
Sbjct: 474 TPGKNSRKKGSVERRSEKDSSHSGRSVVI 502


>gi|224548936 hypothetical protein LOC100170229 [Homo sapiens]
          Length = 715

 Score = 58.5 bits (140), Expect = 2e-08
 Identities = 57/226 (25%), Positives = 90/226 (39%), Gaps = 22/226 (9%)

Query: 373 DWRSRPSRGPALTPIRD-----EEWGGHSPRSPRGWDQEPAREQAGGGWRARRPRARSVD 427
           +W   PS+  + +  R      +  G  SPR   G  Q  +  +     R+R P  ++ D
Sbjct: 354 NWSRNPSKERSHSHSRSSSKERDHRGSSSPRKESGRSQSGSPNKQRDHSRSRSPN-KARD 412

Query: 428 ALDDLTPPSTAE-SGSRSPTSNGGRSRAYMPPRSRSRDDLYDQDDSRDFPRSRDPHYDDF 486
                +P    + S SRSP      SR+  P ++R R      + +RD  RSR P+    
Sbjct: 413 RSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSPNKARD 472

Query: 487 RSRERPPADPRSH-----------HHRTRDP----RDNGSRSGDLPYDGRLLEEAVRKKG 531
           RSR R P+  R H           H R+R P    +   SRS     D R      +++ 
Sbjct: 473 RSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQ 532

Query: 532 SEERRRPHKEEEEEAYYPPAPPPYSETDSQASRERRLKKNLALSRE 577
             + R P+KE +      P+           S+ER  ++  + S+E
Sbjct: 533 RRQSRSPNKERDRSQSRSPSEEREHRQSRSPSKERDRRRWRSPSKE 578



 Score = 44.3 bits (103), Expect = 3e-04
 Identities = 57/231 (24%), Positives = 80/231 (34%), Gaps = 25/231 (10%)

Query: 348 DPSRPGPPSGRVERAMSEVTSLHEDDWRSR-PSRGPALTPIRDEEWGGHSPRSPRGWDQE 406
           D SR   PS   + +     S   D  RSR PS+       R         RS     + 
Sbjct: 472 DRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRS-----RS 526

Query: 407 PAREQAGGGWRARRPRARSVDALDDLTPPSTAESG-SRSPTSNGGRSRAYMPPRSRSRDD 465
           P++E+     R  R   +  D     +P    E   SRSP+    R R   P + R R  
Sbjct: 527 PSKERQR---RQSRSPNKERDRSQSRSPSEEREHRQSRSPSKERDRRRWRSPSKERERRQ 583

Query: 466 LYDQDDSRDFPRSRDPHYDDFRSRERPPADPRSHHHRTRDPRDNGSRS------------ 513
                + RD  RSR P+     SR R  +  ++ H R+R P   G+ S            
Sbjct: 584 SRSSSEERDHSRSRSPNKQSGYSRPRASSKEKA-HSRSRTPSKEGNHSQSRTSSKESDPS 642

Query: 514 -GDLPYDGRLLEEAVRKKGSEERRRPHK-EEEEEAYYPPAPPPYSETDSQA 562
              +P          R     + R P K      + +P      S+ DSQA
Sbjct: 643 QSTVPRSPDWKRSPTRTSSLSQNRTPSKTSSHSPSTFPSGGQTLSQDDSQA 693



 Score = 38.5 bits (88), Expect = 0.017
 Identities = 48/204 (23%), Positives = 75/204 (36%), Gaps = 21/204 (10%)

Query: 396 SPRSPRGWDQEPAREQAGGGWRARRPRARSVDALDDLTP---PSTAESGSRSPTSNG--- 449
           S   PR   ++  R   G G       A +       TP   PS  +S + SP+S+    
Sbjct: 184 SDSQPRNLSKKSYRPPGGSGIGRSSELAVTPSTAKCQTPTGIPSKEKSDNPSPSSSRKVK 243

Query: 450 --------GRSRAYMPPRSRSRDDLYDQDDSRDFP----RSRDPHYDDFRSRERPPADPR 497
                    R ++Y P    SR   Y+Q  +R  P    +SR P      S++R  +  R
Sbjct: 244 SYGQMIIPSREKSYSPTEMSSRVKSYNQASTRSRPQSHSQSRSPRRSRSGSQKRTHSRVR 303

Query: 498 SHHHRTRDPRDNG-SRSGDLPYDGRLLEEAVRKKGSEER--RRPHKEEEEEAYYPPAPPP 554
           SH  +    R    +R G L   GR  +     KG  +   R P +         P+   
Sbjct: 304 SHSWKRNHSRARSRTRKGILSQMGRHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNPSKER 363

Query: 555 YSETDSQASRERRLKKNLALSRES 578
                  +S+ER  + + +  +ES
Sbjct: 364 SHSHSRSSSKERDHRGSSSPRKES 387



 Score = 35.4 bits (80), Expect = 0.15
 Identities = 58/266 (21%), Positives = 86/266 (32%), Gaps = 63/266 (23%)

Query: 364 SEVTSLHEDDWRSRPSRGPALTPIRDEEWGGHSPRSPRGWDQEPAREQAGG-GWRARRPR 422
           S V S ++   RSRP                 SPR  R   Q+    +     W+    R
Sbjct: 264 SRVKSYNQASTRSRPQSHSQ----------SRSPRRSRSGSQKRTHSRVRSHSWKRNHSR 313

Query: 423 ARSVDALDDLTP-----------PSTAESGSR---------------------------- 443
           ARS      L+               +++ SR                            
Sbjct: 314 ARSRTRKGILSQMGRHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSSK 373

Query: 444 --------SPTSNGGRSRAYMPPRSRSRDDLYDQDDSRDFPRSRDPHYDDFRSRERPPAD 495
                   SP    GRS++  P + R        + +RD  RSR P+    RSR R P  
Sbjct: 374 ERDHRGSSSPRKESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRSPYKARDRSRSRSPNK 433

Query: 496 PRSHHHRTRDP---RDNG-SRSGDLPYDGRLLEEAVRKKGSEERRRPHKEEEEEAYYPPA 551
            R    R+R P   RD   SRS +   D        + +     R P KE +      P+
Sbjct: 434 ARD-CSRSRSPYKARDRSRSRSPNKARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPS 492

Query: 552 PPPYSETDSQASRERRLKKNLALSRE 577
                      S+ER+ +++ + S+E
Sbjct: 493 KERDHRRSRSPSKERQCRQSRSSSKE 518


>gi|150418009 transforming, acidic coiled-coil containing protein 2
           isoform a [Homo sapiens]
          Length = 2948

 Score = 54.3 bits (129), Expect = 3e-07
 Identities = 85/328 (25%), Positives = 117/328 (35%), Gaps = 54/328 (16%)

Query: 238 VLVYAAGKAATSGVP-----SIYAPSTYAHLSPAKTPPPPAMIPMGPAYNGYPGGYPGDV 292
           V+  AAG     G+P     S+  P+  AH + +    P A IP+           PG  
Sbjct: 388 VVCVAAGGQPEGGLPVSPEPSLLTPTEEAHPASSLASFPAAQIPIAVEE-------PGSS 440

Query: 293 DRSS-SAGGQGSYVPLLRDTDSSVASEVRSGYRIQASQQDDSMRVLYYMEKELANFDPSR 351
            R S S  G    +P+  D    V      G   Q S            + E    DP  
Sbjct: 441 SRESVSKAG----MPVSADAAKEVVDAGLVGLERQVSDLGS--------KGEHPEGDPGE 488

Query: 352 PGPPSGRVERAMSEVTSLHEDDWRSRPSRGPALTP---IRDEEWGGHSPRSPRGWDQEPA 408
              PS +           HE     +P   P   P     + + G   P  P+    E A
Sbjct: 489 VPAPSPQERGEHLNTEQSHE----VQPGVPPPPLPKEQSHEVQPGAPPPPLPKA-PSESA 543

Query: 409 REQAGGGWRARRPRARSVDALDDLTPPSTAESGSRSP-TSNGGRSRAYMPPRSRSRDDLY 467
           R   G    A+          +D T P+ A+ GSRSP  S GG+  A  PP      +L 
Sbjct: 544 RGPPGPTDGAK--------VHEDSTSPAVAKEGSRSPGDSPGGKEEAPEPPDGGDPGNL- 594

Query: 468 DQDDSRDFPRSRDPHY-DDFRSRERPPADPRSH--HHRTRDPRDNGSRSGDLPYDGRLLE 524
             +DS+ F   RDP    D  S+    A+ R H   H  + PR  G+   D P+      
Sbjct: 595 QGEDSQAFSSKRDPEVGKDELSKPSSDAESRDHPSSHSAQPPRKGGAGHTDGPHS----- 649

Query: 525 EAVRKKGSEERRRPHKEEEEEAYYPPAP 552
              +   ++    PHK  EE+   PP P
Sbjct: 650 ---QTAEADASGLPHKLGEEDPVLPPVP 674


>gi|5031561 transmembrane glycoprotein A33 precursor [Homo sapiens]
          Length = 319

 Score = 50.8 bits (120), Expect = 3e-06
 Identities = 43/173 (24%), Positives = 67/173 (38%), Gaps = 45/173 (26%)

Query: 75  VWLLLSTWCTAPARAIQVTVSNPYHVVILFQ--PVTLPCTYQMTSTPTQPIVIWKYKSFC 132
           +W +L T C        ++V  P  V+   Q   VTLPCTY  +++  + ++ W      
Sbjct: 5   MWPVLWTLCAVRVTVDAISVETPQDVLRASQGKSVTLPCTYHTSTSSREGLIQW------ 58

Query: 133 RDRIADAFSPASVDNQLNAQLAAGNPGYNPYVECQDSVRTVRVVATKQGNAVTLGDYYQG 192
            D++                                   T RVV     N   +      
Sbjct: 59  -DKLL-------------------------------LTHTERVVIWPFSNKNYIHGELYK 86

Query: 193 RRITITGNAD-----LTFDQTAWGDSGVYYCSVVSAQDLQGNNEAYAELIVLV 240
            R++I+ NA+     +T DQ    D+G Y CSV    DL+GN ++   L+VLV
Sbjct: 87  NRVSISNNAEQSDASITIDQLTMADNGTYECSVSLMSDLEGNTKSRVRLLVLV 139


>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
          Length = 2752

 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 69/231 (29%), Positives = 83/231 (35%), Gaps = 34/231 (14%)

Query: 345 ANFDPSRPGPPSGRVERAMSEVTSLHEDDWRSRP-------SRGPALTPIRD-EEWG-GH 395
           A  D S    PS R+ R+ S  T+         P       SR P     R  + WG   
Sbjct: 467 AKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSR 526

Query: 396 SP------RSPR--GWDQEPAREQAGGGWRARRPRARSVDALD-----DLTPPSTAESGS 442
           SP      RSP+  GW +    ++ G    ARR R+ S            TP     S S
Sbjct: 527 SPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRS 586

Query: 443 RSPTSNGGRSRAYMPPRSRSRDDLYDQDDSRDFPRSRDPHYDDFRSRERPPADPRSHHHR 502
           R+P     RSR     RSRSR         R   RSR P     RSR R P   RS   R
Sbjct: 587 RTPARRRSRSRTPTRRRSRSRTPA-----RRGRSRSRTPARR--RSRTRSPVRRRS---R 636

Query: 503 TRDP--RDNGSRSGDLPYDGRLLEEAVRKKGSEERRRPHKEEEEEAYYPPA 551
           +R P  R   SRS      GR       ++G    R P +         PA
Sbjct: 637 SRSPARRSGRSRSRTPARRGRSRSRTPARRGRSRSRTPARRSGRSRSRTPA 687



 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 61/218 (27%), Positives = 82/218 (37%), Gaps = 27/218 (12%)

Query: 375 RSRPSRGPALTPIRDEEWGGHSPRSPRG--WDQEPA-REQAGGGWRARRPRARSVDALDD 431
           RSR  + P  +  R+ +  G S  + RG    + PA R ++     ARR R+RS      
Sbjct: 533 RSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRS------ 586

Query: 432 LTPPSTAESGSRSPT---------SNGGRSRAYMPPRSRSRDDLYDQDDSRDFPRSRDPH 482
              P+   S SR+PT         +  GRSR+  P R RSR     +   R   RSR P 
Sbjct: 587 -RTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRT----RSPVRRRSRSRSPA 641

Query: 483 YDDFRSRERPPADPRSHHHRTRDPRDNGSRSGDLP--YDGRLLEEAVRKKGSEERRRPHK 540
               RSR R PA  R    R+R P   G      P    GR       ++G    R P +
Sbjct: 642 RRSGRSRSRTPA--RRGRSRSRTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRR 699

Query: 541 EEEEEAYYPPAPPPYSETDSQASRERRLKKNLALSRES 578
                         +S T  +  R     +    SR S
Sbjct: 700 GRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTS 737



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 53/190 (27%), Positives = 66/190 (34%), Gaps = 24/190 (12%)

Query: 350 SRPGPPSGRVERAMSEVTSLHEDDWRSRPSRGPALTPIRDEEWGGHSPRSPRGWDQEPAR 409
           SR   P+ R  R+ +           +R  R  + TP R       SP   R   + PAR
Sbjct: 584 SRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRS-RTRSPVRRRSRSRSPAR 642

Query: 410 EQAGGGWR--ARRPRARSVDALDDLTPPSTAESGSRSPTSNGGRSRAYMPPRSRSRDDLY 467
                  R  ARR R+RS       TP     S SR+P    GRSR+  P R        
Sbjct: 643 RSGRSRSRTPARRGRSRS------RTPARRGRSRSRTPARRSGRSRSRTPAR-------- 688

Query: 468 DQDDSRDFPRSRDPHYDDFRSRERPPADPRSHHHRTRDPRDNGSRSGDLPYDGRLLEEAV 527
                R   RSR P     RSR R        H RT   R     S +     R  +   
Sbjct: 689 -----RGRSRSRTPRRG--RSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRS 741

Query: 528 RKKGSEERRR 537
           R   S E ++
Sbjct: 742 RSNSSPEMKK 751



 Score = 38.1 bits (87), Expect = 0.022
 Identities = 48/183 (26%), Positives = 71/183 (38%), Gaps = 22/183 (12%)

Query: 396  SPRSPRGWDQ--EPAREQAGGGWR------ARRP---RARSVDALD-DLTPPSTAESGSR 443
            SP SP   ++   P RE++G          AR P   R+RS  + + D+ P ++ +  S 
Sbjct: 1499 SPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDVKPSASPQERSE 1558

Query: 444  SPTSNGGRSRAYMPPRSRSRDDLYDQDDSRD--FPRSRDPHYDDFRSRERPPADPRSHHH 501
            S +S   +++   P R RSR     + DS+    PR R         +++P A PR+   
Sbjct: 1559 SDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPR-RSRSGSSPEVKDKPRAAPRAQSG 1617

Query: 502  RTRDPRDNGSRSGDLPYDGRLLEEAVRKKGSEERRRPHKEEEEEAYYPPAPPPYSETDSQ 561
                P              R L    R   S + R P  E        P  PP S T  +
Sbjct: 1618 SDSSPEPKAPAP-------RALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARR 1670

Query: 562  ASR 564
             SR
Sbjct: 1671 GSR 1673



 Score = 37.4 bits (85), Expect = 0.038
 Identities = 56/224 (25%), Positives = 79/224 (35%), Gaps = 31/224 (13%)

Query: 350  SRPGPPSGRVERAMSEVTSLHEDDWRSRP-------SRGPALTPIRDEEWGGHSPRSPRG 402
            SR  P S R  R+ + VT       R+ P       SR P +T  R       + R  R 
Sbjct: 1890 SRTSPVSRRRSRSRTSVTRRRSRS-RASPVSRRRSRSRTPPVTRRRSRSRTPTTRRRSRS 1948

Query: 403  WDQEPAREQAGGGWRARRPRARSVDALDDLTPPSTAESGSRSPTSNGGRSRAYMPPRSRS 462
                  R ++    R+R P      +    +P +   S SR+      RSR+   P +R 
Sbjct: 1949 RTPPVTRRRS----RSRTPPVTRRRSRSRTSPITRRRSRSRTSPVTRRRSRSRTSPVTRR 2004

Query: 463  RDDLYDQDDSRDFPRSRDPHYDDFRSRERPPADPRSHHHRTRDPRDNGSRSGDLPYDGRL 522
            R        +R   RSR P     RSR R P  PR    R+R P                
Sbjct: 2005 RSRSRTSPVTRRRSRSRTPPAIRRRSRSRTPLLPRK-RSRSRSPL--------------- 2048

Query: 523  LEEAVRKKGSEERRRPHKEEEEEAYYPPAPPPYSETDSQASRER 566
               A+R++      R  + +      PPA    S + S + R R
Sbjct: 2049 ---AIRRRSRSRTPRTARGKRSLTRSPPAIRRRSASGSSSDRSR 2089



 Score = 36.2 bits (82), Expect = 0.085
 Identities = 57/234 (24%), Positives = 77/234 (32%), Gaps = 50/234 (21%)

Query: 385  TPIRDEEWGGHSPRSPRGWDQEPAREQAGG---------GWRARRPRARSVDALDDL--T 433
            TP R+      SP    G  + P+R    G         G  +R   + S   + D+  T
Sbjct: 1413 TPSRERSSSASSPEMKDGLPRTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRT 1472

Query: 434  P----------------PSTAESGSRSPTSNGGRSRAYMPPRSRS-RDDLYDQDDSRDFP 476
            P                P T    SRSP+S    ++   P R RS  +   DQ      P
Sbjct: 1473 PSRGRSECDSSPEPKALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTP 1532

Query: 477  ---RSRDPHYDDFRSRERPPADPRSHHH---------RTRDPRDNGSRSGDLPYDGRLLE 524
               RSR     +     +P A P+             +TR P    SRSG  P       
Sbjct: 1533 LGQRSRSGSSQEL--DVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSP------- 1583

Query: 525  EAVRKKGSEERRRPHKEEEEEAYYPPAPPPYSETDSQASRERRLKKNLALSRES 578
              V  K     RR       E    P   P +++ S +S E +     AL R S
Sbjct: 1584 -EVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRS 1636



 Score = 36.2 bits (82), Expect = 0.085
 Identities = 60/224 (26%), Positives = 75/224 (33%), Gaps = 23/224 (10%)

Query: 350  SRPGPPSGRVERAMSEVTSLHEDDWRSRPSRGPALTPIRDEEWGGHSPRSPRGWDQEPAR 409
            SR      R  R      S      R + SR  +    R     G+  RSP    QE +R
Sbjct: 1775 SRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPAR--QESSR 1832

Query: 410  EQAGGGWRARRPRARSVDALDDLTPPSTAESGSRSPTSNGGRSRAYMPP----RSRSRDD 465
              +    R RR R+R+        P S   S SR+  +   RSR+   P    RSRSR  
Sbjct: 1833 TSS----RRRRGRSRT-------PPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTP 1881

Query: 466  LYDQDDSRDFPRSRDPHYDDFRSRERPPADPRSHHHRTRDPRDNGSRSGDLPYDGRLLEE 525
            L     SR   RSR       RSR R     R    R        SRS   P   R    
Sbjct: 1882 LI----SRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRS 1937

Query: 526  --AVRKKGSEERRRPHKEEEEEAYYPPAPPPYSETDSQASRERR 567
                 ++ S  R  P       +  PP     S + +     RR
Sbjct: 1938 RTPTTRRRSRSRTPPVTRRRSRSRTPPVTRRRSRSRTSPITRRR 1981



 Score = 33.1 bits (74), Expect = 0.72
 Identities = 47/199 (23%), Positives = 67/199 (33%), Gaps = 21/199 (10%)

Query: 376  SRPSRGPALTPIRDEEWGGHSPRSPRGWDQEPAREQAGGGWRAR-RPRARSVDALDDLTP 434
            S  S+    TP+R     G SP         P R ++G     + +PRA           
Sbjct: 1562 SPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRA----------- 1610

Query: 435  PSTAESGSRSPTSNGGRSRAYMPPRSRS------RDDLYDQDDSRDFPRSRDPHYDDFRS 488
               A+SGS S       +   +P RSRS      R    +   S +      P     R 
Sbjct: 1611 APRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARR 1670

Query: 489  RERPPADPRSHHHRTRDPRDNGSRSGDLPYDGRLLEEAVRKKGSEERRRPHKEEEEEAYY 548
              R   +P++   RT   R +   S +L    RL   +     S E R         +  
Sbjct: 1671 GSRSSPEPKT-KSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRS-- 1727

Query: 549  PPAPPPYSETDSQASRERR 567
            P    P     S++SR RR
Sbjct: 1728 PSVSSPEPAEKSRSSRRRR 1746



 Score = 29.6 bits (65), Expect = 8.0
 Identities = 56/231 (24%), Positives = 81/231 (35%), Gaps = 32/231 (13%)

Query: 345 ANFDPSRPGPPSGRVERAMSEVTSLHEDDWRSRPSRGPALTPIRDEEWGGHSPRSPRGWD 404
           ++FDP R    + +      +  SL  +   S  SR P  TP + ++      R  R   
Sbjct: 149 SSFDPQRRAREAKQPAPEPPKPYSLVRE---SSSSRSP--TP-KQKKKKKKKDRGRRSES 202

Query: 405 QEPAREQAGGGWRARRPRARSVDALDDLTPPSTAESGSRSPTSNGGRSRAYMPP------ 458
             P RE+     + ++ R+ S         P T +S  +S      RSR+  P       
Sbjct: 203 SSPRRERKKSS-KKKKHRSESESKKRKHRSP-TPKSKRKSKDKKRKRSRSTTPAPKSRRA 260

Query: 459 -RSRSRDDLYDQDDSRDFPRSR--DPHYDDFRSRERPPAD--------PRSHHHRTRDPR 507
            RS S D     D SR   RS     H      R   PA         P S    T   R
Sbjct: 261 HRSTSADSASSSDTSRSRSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQR 320

Query: 508 ----DNGSRSGDLPYDGRLLEEAVRKKGSEERRRPHKEEEEEAYYPPAPPP 554
               +  ++    PY+ +   +  +K+ S  R  P  E       PPAP P
Sbjct: 321 PSSPETATKQPSSPYEDK---DKDKKEKSATRPSPSPERSSTGPEPPAPTP 368


>gi|153251865 hypothetical protein LOC84226 [Homo sapiens]
          Length = 1984

 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 63/229 (27%), Positives = 85/229 (37%), Gaps = 24/229 (10%)

Query: 367  TSLHEDDWRSRPSRGPALTPIRD----EEWGGHSP--RSPRGWDQEPAREQAGGGWRARR 420
            +S  E  WRS   R     P R      E G HSP  RS RG  Q   R  +      R 
Sbjct: 1599 SSPSERSWRSPSQRNHCSPPERSCHSLSERGLHSPSQRSHRGPSQR--RHHSPSERSHRS 1656

Query: 421  PRARSVDALDDLTPPSTAESGSRSPTSNGGRSRAYMPPRSRSRDDLYDQDDSRDFPRSRD 480
            P  RS  +  +    S ++   R P+     S +    RS S+       + R    S+ 
Sbjct: 1657 PSERSHRSSSERRHRSPSQRSHRGPSERSHCSPSERRHRSPSQRSHRGPSERRHHSPSKR 1716

Query: 481  PHYDDFRSRERPPADPRSHH------HRTRDPRDNGS---RSGDLPYDGRLLEEAVRKKG 531
             H    R   R P++ RSHH      H +   R + S   RS   P +      + R+  
Sbjct: 1717 SHRSPARRSHRSPSE-RSHHSPSERSHHSPSERRHHSPSERSHCSPSERSHCSPSERRHR 1775

Query: 532  SEERRRPHKEEEEEAYYPPAPPPYSETDSQASRERRLKKNLALSRESLV 580
            S   RR H   E+  + P      SE    +  ERR    L  SR SL+
Sbjct: 1776 SPSERRHHSPSEKSHHSP------SERSHHSPSERRRHSPLERSRHSLL 1818



 Score = 33.5 bits (75), Expect = 0.55
 Identities = 57/212 (26%), Positives = 74/212 (34%), Gaps = 19/212 (8%)

Query: 343  ELANFDPS--RPGPPSGRVERAMSEVTSLHEDDWRSRPSRGPALTPIRDEEWGGHSPRSP 400
            E ++  PS  R   PS R  R  SE    H    RS   R PA    R      H   S 
Sbjct: 1683 ERSHCSPSERRHRSPSQRSHRGPSERRH-HSPSKRSH--RSPARRSHRSPSERSHHSPSE 1739

Query: 401  RGWDQEPAREQAGGGWRARRPRARSVDALDDLTPPSTAESGSRSPTSNGGRS---RAYMP 457
            R       R       R   P  RS  +  + +  S +E   RSP+     S   +++  
Sbjct: 1740 RSHHSPSER-------RHHSPSERSHCSPSERSHCSPSERRHRSPSERRHHSPSEKSHHS 1792

Query: 458  PRSRSRDDLYDQDDSRDFPRSRDPHYDDFRSRERPPADPRSHHHRTRDPRDNGSRSGDLP 517
            P  RS       +  R  P  R  H    RS  R P++ RSH    R  R    RS   P
Sbjct: 1793 PSERSHHS--PSERRRHSPLERSRHSLLERSH-RSPSERRSHRSFERSHRRISERSHS-P 1848

Query: 518  YDGRLLEEAVRKKGSEERRRPHKEEEEEAYYP 549
             +   L    R + S   RR H    +  + P
Sbjct: 1849 SEKSHLSPLERSRCSPSERRGHSSSGKTCHSP 1880


>gi|4503509 eukaryotic translation initiation factor 3, subunit 10
            theta, 150/170kDa [Homo sapiens]
          Length = 1382

 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 58/214 (27%), Positives = 75/214 (35%), Gaps = 36/214 (16%)

Query: 348  DPSRPGPPSGRVERAMSEVTSLHEDDWRSRPSRGPALTPIRDEEWGG---HSPRSPRGWD 404
            D SRPGP    V+             WR +          R+E WG      P   R WD
Sbjct: 1162 DDSRPGPWRPLVKPG----------GWREKEKA-------REESWGPPRESRPSEEREWD 1204

Query: 405  QEPAR-------EQAGGGWRARRPRARSVDALDDLTPPSTAESGSRSPTSNGGRSRAYMP 457
            +E  R       E+        R R R VD  D    P       R P       R    
Sbjct: 1205 REKERDRDNQDREENDKDPERERDRERDVDREDRFRRPRDEGGWRRGPAEESSSWRDSSR 1264

Query: 458  PRSRSRDD-LYDQDDSRDFPRSRDPHYDDFRSRERPP----ADPRSHHHRTRDPRDNGSR 512
               R RDD   ++DD RD    RD    D R R  PP     +  S   R  D +D+   
Sbjct: 1265 RDDRDRDDRRRERDDRRDLRERRD--LRDDRDRRGPPLRSEREEVSSWRRADDRKDDRVE 1322

Query: 513  SGDLPYDGRLLEEAVRKKGSEERRRPHKEEEEEA 546
              D P   R+   A+ +    +R R  + E+E+A
Sbjct: 1323 ERDPP--RRVPPPALSRDRERDRDREREGEKEKA 1354



 Score = 33.1 bits (74), Expect = 0.72
 Identities = 56/253 (22%), Positives = 88/253 (34%), Gaps = 44/253 (17%)

Query: 298 AGGQGSYVPLLRDTDSSVASEVRSGYRIQASQQDDSMRVLYYMEKELANFDPSRPGPPSG 357
           A  Q  Y   L+  +  +A E  +    +  Q+ +  R+ YY EKE              
Sbjct: 766 AARQSVYEEKLKQFEERLAEERHNRLEERKRQRKEERRITYYREKE-------------- 811

Query: 358 RVERAMSEVTSLHEDDWRSRPSRGPALTPIRDEEWGGHSPRSPRGWDQEPAREQAGGGWR 417
             E+  +E   L E + R R  R       R+EE   +  R  +  + E  + Q      
Sbjct: 812 EEEQRRAEEQMLKEREERERAERAK-----REEELREYQERVKKLEEVERKKRQRELEIE 866

Query: 418 ARRPRARSVDALDDLTPPSTAESGSRSPTSNGGRSRAYMPPRSRSRDDLYDQDDSRDFPR 477
            R  R      L D        S SR  +  G           R  +  + +    D   
Sbjct: 867 ERERRREEERRLGD-------SSLSRKDSRWG----------DRDSEGTWRKGPEADSEW 909

Query: 478 SRDPHYDDFRSRERPPADPRSHHHRTRDPR---DNGSRSGDLPYDGRLLEEAVRKKGSEE 534
            R P   ++R  E    D RSH      PR   D+  R   L  D    ++ V ++G ++
Sbjct: 910 RRGPPEKEWRRGEGRDED-RSHRRDEERPRRLGDDEDREPSLRPD----DDRVPRRGMDD 964

Query: 535 RRRPHKEEEEEAY 547
            R P +  EE+ +
Sbjct: 965 DRGPRRGPEEDRF 977


>gi|29568103 U1 small nuclear ribonucleoprotein 70 kDa [Homo
           sapiens]
          Length = 437

 Score = 47.0 bits (110), Expect = 5e-05
 Identities = 65/238 (27%), Positives = 91/238 (38%), Gaps = 41/238 (17%)

Query: 318 EVRSGYRIQASQQDDSMRVLYYMEK--ELANFDPSRPGPPSGRVERAMSEVTSLH---ED 372
           ++ S Y+    ++ D  RVL  +E+   +  + P R G   G   R  ++V   H   +D
Sbjct: 156 DMHSAYKHADGKKIDGRRVLVDVERGRTVKGWRPRRLGGGLGGTRRGGADVNIRHSGRDD 215

Query: 373 DWRSRPSRGPALTPIRDEEWGGHSPRSPRGWDQEPAREQAGGGWRARRPRARSVDALDDL 432
             R     GP+  P RD +      R  R  +++  RE+     R RR R+RS D     
Sbjct: 216 TSRYDERPGPSPLPHRDRDRDRERERRERSRERDKERERRRSRSRDRRRRSRSRD----- 270

Query: 433 TPPSTAESGSRSPTSNGGRSRAYMPPRSRSRDDLYDQDDSRDFPRSRDPHYDDFRSRERP 492
                 E   RS              R RS+D   D+D  R   RSR+      R RER 
Sbjct: 271 -----KEERRRS--------------RERSKDK--DRDRKRRSSRSRERAR---RERERK 306

Query: 493 P------ADPRSHHHRTRDPRDNGSRSGDLPYDGRLLEEAVRKKGSEERRRPHKEEEE 544
                   D          P D+G   G+L  DG    E   +    ERRR H+ E E
Sbjct: 307 EELRGGGGDMAEPSEAGDAPPDDGP-PGELGPDGPDGPEEKGRDRDRERRRSHRSERE 363


>gi|65301122 MARVEL domain containing 3 isoform 1 [Homo sapiens]
          Length = 410

 Score = 46.6 bits (109), Expect = 6e-05
 Identities = 49/172 (28%), Positives = 59/172 (34%), Gaps = 37/172 (21%)

Query: 418 ARRPRARSVDALDDLTPPSTAESGSRSPTSNGGRSRAYMPPRSRSRDDLYDQDDSRDFPR 477
           AR PRAR  +       P       +  T +  R R   P R RS D    +D  RD  R
Sbjct: 7   AREPRARPRER-----DPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPER 61

Query: 478 ------SRDPHYDDFRSRER---PPADPRSHHHRTRDPRDNGSRSGDLPYDGRLLEEA-- 526
                 +RD + D  R RER   P   PR   HR   PR       + P   R  + A  
Sbjct: 62  DQERDGNRDRNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSRTRDGARG 121

Query: 527 ---------------------VRKKGSEERRRPHKEEEEEAYYPPAPPPYSE 557
                                 ++KG   RRRP  E   E Y P  P P  E
Sbjct: 122 LTWDAAAPPGPAPWEAPEPPQPQRKGDPGRRRPESEPPSERYLPSTPRPGRE 173


>gi|65293358 MARVEL domain containing 3 isoform 2 [Homo sapiens]
          Length = 401

 Score = 46.6 bits (109), Expect = 6e-05
 Identities = 49/172 (28%), Positives = 59/172 (34%), Gaps = 37/172 (21%)

Query: 418 ARRPRARSVDALDDLTPPSTAESGSRSPTSNGGRSRAYMPPRSRSRDDLYDQDDSRDFPR 477
           AR PRAR  +       P       +  T +  R R   P R RS D    +D  RD  R
Sbjct: 7   AREPRARPRER-----DPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPER 61

Query: 478 ------SRDPHYDDFRSRER---PPADPRSHHHRTRDPRDNGSRSGDLPYDGRLLEEA-- 526
                 +RD + D  R RER   P   PR   HR   PR       + P   R  + A  
Sbjct: 62  DQERDGNRDRNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSRTRDGARG 121

Query: 527 ---------------------VRKKGSEERRRPHKEEEEEAYYPPAPPPYSE 557
                                 ++KG   RRRP  E   E Y P  P P  E
Sbjct: 122 LTWDAAAPPGPAPWEAPEPPQPQRKGDPGRRRPESEPPSERYLPSTPRPGRE 173


>gi|50083281 KIAA1853 protein [Homo sapiens]
          Length = 611

 Score = 43.1 bits (100), Expect = 7e-04
 Identities = 73/313 (23%), Positives = 105/313 (33%), Gaps = 53/313 (16%)

Query: 294 RSSSAGGQGSYVPLLRDTDSSVASEVRSGYRIQASQQDDSMRVLYYMEKELANFDPSRPG 353
           R    G     +   R+ +S   S+  + +   + Q   +M         L N  P+  G
Sbjct: 305 RGQEKGSPSGGLSKSRELNSGNTSDSGNSFTTSSPQNKGAM---------LENLSPTSRG 355

Query: 354 PPSGR-----VERAMSEVTSLHEDDWRSRPSRGPALTP-IRDEEWGGHSPRSPRGWDQEP 407
             S       +E A  + +SL     RS P +G + +          HS RSP      P
Sbjct: 356 RESRGFQSPCLECAEVKKSSLVPSTARSSPMKGCSRSSSYASTRSSSHSSRSPNP-RASP 414

Query: 408 AREQAGGGWRARRPRARSVDALDDLTPPSTAESGSRSPTSNGGRSR------AYMPPRSR 461
              Q+      +R  +RS        P  +++SG RSP S   RSR       Y P  SR
Sbjct: 415 RYTQSRSTSSEKRSYSRS--------PSYSSKSGKRSPPSRSSRSRRSPSYSRYSP--SR 464

Query: 462 SRDDLYDQDDS----RDFPRSRDPHYDDFRSRERPPADPRSHHHRTR------------- 504
            RD  Y + DS    R+  R R   Y   R R R   D  SH    R             
Sbjct: 465 ERDPKYSEKDSQQRERERARRRRRSYSPMRKRRR---DSPSHLEARRITSARKRPIPYYR 521

Query: 505 -DPRDNGSRSGDLPYDGRLLEEAVRKKGSEERRRPHKEEEEEAYYPPAPPPYSETDSQAS 563
             P  +GS S    +       +  +  S  R R             +    S +    S
Sbjct: 522 PSPSSSGSLSSTSSWYSSSSSRSASRSYSRSRSRSRSRRRSRTRTSSSSSSRSPSPGSRS 581

Query: 564 RERRLKKNLALSR 576
           R R   ++ + SR
Sbjct: 582 RSRSRSRSRSRSR 594



 Score = 37.0 bits (84), Expect = 0.050
 Identities = 49/209 (23%), Positives = 73/209 (34%), Gaps = 37/209 (17%)

Query: 375 RSRPSRGPALTPIRD---EEWGGHSPRSPRG---WDQEPAREQAGGGWRARRPRARSVDA 428
           R+ P   P + P +D   E+ G H    P G   W+++    + G        R  S   
Sbjct: 44  RTEPQNNPVV-PAQDGPSEKLGQHLATEPLGTNSWERDKTCRELGA------TRGHSASH 96

Query: 429 LDDLTPPSTA---ESGSRSPTSNGGRSRAYMPP--------------RSRSRDDLYDQDD 471
             DLTPP ++   +   +S      RS +Y P               R RS         
Sbjct: 97  DKDLTPPPSSRGKKKKKKSTRKKRRRSSSYSPSPVKKKKKKSSKKHKRRRSFSKKRRHSS 156

Query: 472 SRDFPRSRDPHYDDFRSRERPPADPRSHHHR---TRDPRDNGSRSGDLPYDGRLLEEAVR 528
           S    + RD      +SR RP    R  HHR        ++   S +  + GR  EE  +
Sbjct: 157 SSPKSKRRDEKRHKKQSRSRPRKSHRHRHHRCPSRSQSSESRPSSCESRHRGRSPEEGQK 216

Query: 529 KKGSEERRRP----HKEEEEEAYYPPAPP 553
            +    RR          E ++  PP+ P
Sbjct: 217 SRRRHSRRCSKTLCKDSPEAQSSRPPSQP 245



 Score = 30.4 bits (67), Expect = 4.7
 Identities = 26/84 (30%), Positives = 32/84 (38%), Gaps = 5/84 (5%)

Query: 435 PSTAESGSRSPTSNGGRSRAYMPPRSRSRDDLYDQDDSRDFPRSRDPHYDDFRSRERPPA 494
           PS + SGS S TS+      Y    SRS    Y +  SR   R R        S  R P+
Sbjct: 522 PSPSSSGSLSSTSSW-----YSSSSSRSASRSYSRSRSRSRSRRRSRTRTSSSSSSRSPS 576

Query: 495 DPRSHHHRTRDPRDNGSRSGDLPY 518
                  R+R    + SRS    Y
Sbjct: 577 PGSRSRSRSRSRSRSRSRSQSRSY 600


>gi|71044479 death inducer-obliterator 1 isoform c [Homo sapiens]
          Length = 2240

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 66/228 (28%), Positives = 76/228 (33%), Gaps = 52/228 (22%)

Query: 295  SSSAGGQGSYVPLLRDTDSSVAS-EVRSG----YRIQASQQDDSMRV-LYYMEKELANFD 348
            SSSA GQG       + D   AS + R G    YR Q  +     R  +   EK L   D
Sbjct: 2051 SSSAPGQGP------EADGQWASADFREGKGHEYRNQTFEGRQRERFDVGPKEKPLEEPD 2104

Query: 349  PSRPGPPSGRVERAMSEVTSLHEDDWRSRPSRGPALTPIRDEEWGGHSPR-SPRGWDQEP 407
                     R ER      S  E DW             R  EW  H  + S R WD+  
Sbjct: 2105 AQGRASEDRRRERERGRNWS-RERDWD------------RPREWDRHRDKDSSRDWDRNR 2151

Query: 408  AREQAGGGWRARRPRARSVDALDDLTPPSTAESGSRSPTSNGGRSRAYMPPRSRSRDDLY 467
             R        A R R R  D                       RSR     R R RD   
Sbjct: 2152 ERS-------ANRDREREADR-----------------GKEWDRSRERSRNRERERDRRR 2187

Query: 468  DQDDSRDFPRSRDPHYDDFRSRERPPADPRSHHHRTRDPRDNGSRSGD 515
            D+D SR   R RD   D  R R+R   D        RDP+   SR+ D
Sbjct: 2188 DRDRSRSRERDRDKARDRERGRDR--KDRSKSKESARDPKPEASRASD 2233



 Score = 31.6 bits (70), Expect = 2.1
 Identities = 45/185 (24%), Positives = 60/185 (32%), Gaps = 22/185 (11%)

Query: 394  GHSPRSPRGWDQEPAREQAGGGWRARRPRARSVDALDDLTPPSTAESGSRSPTSNGGRSR 453
            G  P +   W     RE  G  +R +    R  +  D        E     P + G  S 
Sbjct: 2056 GQGPEADGQWASADFREGKGHEYRNQTFEGRQRERFD----VGPKEKPLEEPDAQGRASE 2111

Query: 454  AYMPPRSRSRDDLYDQDDSRDFPRSRDPHYDD------FRSRERP-------PADPRSHH 500
                 R R R+  + ++   D PR  D H D        R+RER         AD     
Sbjct: 2112 DRRRERERGRN--WSRERDWDRPREWDRHRDKDSSRDWDRNRERSANRDREREADRGKEW 2169

Query: 501  HRTRDPRDNGSRSGDLPYD---GRLLEEAVRKKGSEERRRPHKEEEEEAYYPPAPPPYSE 557
             R+R+   N  R  D   D    R  E    K    ER R  K+  +       P P + 
Sbjct: 2170 DRSRERSRNRERERDRRRDRDRSRSRERDRDKARDRERGRDRKDRSKSKESARDPKPEAS 2229

Query: 558  TDSQA 562
              S A
Sbjct: 2230 RASDA 2234


>gi|154354981 regulating synaptic membrane exocytosis 2 isoform b
           [Homo sapiens]
          Length = 1163

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 44/161 (27%), Positives = 68/161 (42%), Gaps = 21/161 (13%)

Query: 433 TPPSTAESGSRSPTSNGGRSRAYMPPRSRSRDDLYDQDDSRD-----------FPRSRDP 481
           +PP+  ++     T N  R R+  P  SR ++  YDQ + R+            PRS   
Sbjct: 23  SPPNILQNELFGQTLNNARKRS--PSVSRDQNRRYDQREEREEYSQYATSDTAMPRSPSD 80

Query: 482 HYDDFRSRERPPADPRSHHHRTRDPRDNGSR-SGDLPYDGRLLE---EAVRKKGSEERRR 537
            Y D RS+  P     S H   RD      R S +   D   +E   E  R++  EE + 
Sbjct: 81  -YADRRSQHEPQFYEDSDHLSYRDSNRRSHRHSKEYIVDDEDVESRDEYERQRREEEYQS 139

Query: 538 PHKEEEEEAYYPPAPPPYSE---TDSQASRERRLKKNLALS 575
            ++ +   A YP  P PY E     ++ SR R  +++  +S
Sbjct: 140 RYRSDPNLARYPVKPQPYEEQMRIHAEVSRARHERRHSDVS 180


>gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens]
          Length = 953

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 62/228 (27%), Positives = 83/228 (36%), Gaps = 62/228 (27%)

Query: 341 EKELANFDPSRPGPPSGRVERAMSEVTSLHEDDWRSRPSRGPALTPIRDEEW-----GGH 395
           EKE     P  P PPS + E    E             + GP +   R +EW        
Sbjct: 477 EKEKGKPKPRSPQPPSRQAEPPKKEAA-----------TTGPQVK--RADEWKDPWRRSK 523

Query: 396 SPRSPRGWDQEPAREQAGGGWRARRPRARSVDALDDLTPPSTAESGSRSPTSNGGRSRAY 455
           SP+   G    P+R +     R R+  A S  A       +++ S SRS + +G  S   
Sbjct: 524 SPKKKLGVSVSPSRAR-----RRRKTSASSASA------SNSSRSSSRSSSYSGSGS--- 569

Query: 456 MPPRSRSRDDLYDQDDSRDFPRSRDPHYDDFRSRER-----PPADPRSHHHRTRDPRDNG 510
              RSRSR   Y    SR    SR   +   RSR R     P   P    HR    R  G
Sbjct: 570 --SRSRSRSSSYSSYSSRS---SRHSSFSGSRSRSRSFSSSPSPSPTPSPHRP-SIRTKG 623

Query: 511 SRSGDLPYDGRLLEEAVRKKGSEERRRPHKEEEEEAYYPPAPPPYSET 558
             +   P  G+  E++V+K                   PPAPP  ++T
Sbjct: 624 EPA---PPPGKAGEKSVKKPAP----------------PPAPPQATKT 652


>gi|14670268 RD RNA-binding protein [Homo sapiens]
          Length = 380

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 45/146 (30%), Positives = 59/146 (40%), Gaps = 32/146 (21%)

Query: 418 ARRPRARSV--------DALDDLTPPSTAESGSRSPTSNGGRSRAY-------------- 455
           +RRP+ +S+        D L +L P      G   P +  G  R++              
Sbjct: 124 SRRPQRKSLYESFVSSSDRLRELGPDGEEAEG---PGAGDGPPRSFDWGYEERSGAHSSA 180

Query: 456 MPPRSRSRDDLYDQDDSRDFPRSRDPHYDDFRSRERPPADPRSHHHRTRDPRDNGSRSGD 515
            PPRSRSRD  ++++  RD  R RD   D  R RER   D      R RD   +  R  D
Sbjct: 181 SPPRSRSRDRSHERNRDRDRDRERDRDRDRDRDRER---DRDRDRDRDRDRERDRDRERD 237

Query: 516 LPYDGRLLEEAVRKKGS-EERRRPHK 540
              D    E   R+  S  ERR P K
Sbjct: 238 RDRD---REGPFRRSDSFPERRAPRK 260


>gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo
           sapiens]
          Length = 434

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 64/253 (25%), Positives = 92/253 (36%), Gaps = 42/253 (16%)

Query: 338 YYMEKELANFDPSRPGPPSGRVERAMSEVTSLHEDDWRSRPSRGPALTPIRDEEWGGHSP 397
           +Y      + +  R     GR  R+ S        + R   S+  +    + EE      
Sbjct: 39  HYSRSRSRSRERKRKSDNEGRKHRSRSR-----SKEGRRHESKDKSSKKHKSEEHNDKEH 93

Query: 398 RSPRGWDQEPAREQAGGGWRARRPRARSVDALDDLTPPSTAESGSRSPTS---NGGRSRA 454
            S +G  +E       G  R +R   +S          S   S SRS +    +  RSR 
Sbjct: 94  SSDKG--RERLNSSENGEDRHKRKERKS----------SRGRSHSRSRSRERRHRSRSRE 141

Query: 455 YMPPRSRSRDDLYDQDDSRDFPRSRDPHYDDFRSRERPPADPRSHHHRTRDPRDNGSRSG 514
               RSRSR+    +  SR+  +SR    +  R           H HRTR      SRS 
Sbjct: 142 RKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRTRSRSR 201

Query: 515 DLPYDGRLLEEAVRKKGSEERRRPHKEEEEEAYYPPAPPPY----SETDSQASRERRLK- 569
           D            RKK  E+ RR  +         P+PPP+    +  D+Q +  RRL+ 
Sbjct: 202 D------------RKKRIEKPRRFSRSLSRT----PSPPPFRGRNTAMDAQEALARRLER 245

Query: 570 -KNLALSRESLVV 581
            K L   RE  +V
Sbjct: 246 AKKLQEQREKEMV 258



 Score = 30.8 bits (68), Expect = 3.6
 Identities = 34/125 (27%), Positives = 48/125 (38%), Gaps = 7/125 (5%)

Query: 460 SRSRDDLYDQDDSRDFPRSRDPHYDDFRSRERP---PADPRSHHHRTRDPRDNGSR--SG 514
           S  RD   +Q +    PR+   HY   RSR R     +D     HR+R     G R  S 
Sbjct: 17  SPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSRSRSKEGRRHESK 76

Query: 515 DLPYDGRLLEEAVRKKGSEE--RRRPHKEEEEEAYYPPAPPPYSETDSQASRERRLKKNL 572
           D        EE   K+ S +  R R +  E  E  +       S   S +    R +++ 
Sbjct: 77  DKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRERRHR 136

Query: 573 ALSRE 577
           + SRE
Sbjct: 137 SRSRE 141



 Score = 30.0 bits (66), Expect = 6.1
 Identities = 31/142 (21%), Positives = 53/142 (37%), Gaps = 11/142 (7%)

Query: 443 RSPTSNGGRSRAYMPPRSRSRDDLYDQDDSRDFPRSRDPHYDDFRSRERPPADPRSHHHR 502
           R+   +  RSR+    RSR R    D +  +   RSR        S+++     +S  H 
Sbjct: 34  RASKHHYSRSRS----RSRERKRKSDNEGRKHRSRSRSKEGRRHESKDKSSKKHKSEEHN 89

Query: 503 TRD-------PRDNGSRSGDLPYDGRLLEEAVRKKGSEERRRPHKEEEEEAYYPPAPPPY 555
            ++        R N S +G+  +  +  + +  +  S  R R  +          +    
Sbjct: 90  DKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRS 149

Query: 556 SETDSQASRERRLKKNLALSRE 577
            E     SR R  KK+ + SRE
Sbjct: 150 RERKKSRSRSRERKKSRSRSRE 171


>gi|20127499 arginine/serine-rich splicing factor 6 [Homo sapiens]
          Length = 344

 Score = 42.0 bits (97), Expect = 0.002
 Identities = 42/149 (28%), Positives = 55/149 (36%), Gaps = 13/149 (8%)

Query: 436 STAESGSRSPTSNGGRSRAYMPPRSRSRDDLYDQDDSRDFPRSRDPHYDDFRSRERPPAD 495
           S   S SRS  S+  RSR+    RSRSR     +  SR   R         +S+ +P +D
Sbjct: 200 SRRRSRSRSRRSSRSRSRSISKSRSRSRSRSKGRSRSRSKGRK-----SRSKSKSKPKSD 254

Query: 496 PRSHHHRTRDPRDNGSRSGDLPYDGRLLEEAVRKKGSEERRRPHKEEEEEAYYPP----- 550
             SH H     +D   +S          E       S+ R R           PP     
Sbjct: 255 RGSHSHSRSRSKDEYEKSRSRSRSRSPKENGKGDIKSKSRSRSQSRSNSPLPVPPSKARS 314

Query: 551 -APPPYSETDSQASRERRLKKNLALSRES 578
            +PPP   T    SR R   K+ + SR S
Sbjct: 315 VSPPPKRATSRSRSRSR--SKSRSRSRSS 341


>gi|50053795 eukaryotic translation initiation factor 4B [Homo
           sapiens]
          Length = 611

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 74/303 (24%), Positives = 113/303 (37%), Gaps = 41/303 (13%)

Query: 275 IPMGPAYNGYPGGYPGDV-DRSSSAGGQGSYVPLLRDTDSSVASEVRSGYRIQASQQDDS 333
           +P  P Y  + G  P DV + S     +G  +  +R        E   G+     +  DS
Sbjct: 90  LPKSPPYTAFLGNLPYDVTEESIKEFFRGLNISAVRLPREPSNPERLKGFGYAEFEDLDS 149

Query: 334 M-RVLYYMEKELANF-----------DPSRPGPPSGRVERAMSEVTSLHEDDWRSRPSRG 381
           +   L   E+ L N            D  R     GR     S+ T   + DWR+RP+  
Sbjct: 150 LLSALSLNEESLGNRRIRVDVADQAQDKDRDDRSFGRDRNRDSDKT---DTDWRARPATD 206

Query: 382 PA--LTPIRDEEWGGHSPR----SPR-------GWDQEPAREQAGGGWRARRPRARSVDA 428
                 P R ++  G   R    S R       G+   P R+    G R R     S D 
Sbjct: 207 SFDDYPPRRGDDSFGDKYRDRYDSDRYRDGYRDGYRDGPRRDMDRYGGRDRYDDRGSRDY 266

Query: 429 LDDLTPPSTAESGSRSPTSNGGRSRAYMPPRSRSRDDLYDQDDSRDFPRSRDPHYDDFRS 488
             D    S   SG R+  S   R   Y     R  +D YD+ D R +    D   DD+R 
Sbjct: 267 --DRGYDSRIGSGRRAFGSGYRRDDDYRGGGDRY-EDRYDRRDDRSWSSRDDYSRDDYRR 323

Query: 489 RER-PPADPRSHHHRTRDPRDNGS--------RSGDLPYDGRLLEEAVRKKGSEERRRPH 539
            +R PP  P+ +      P+++ S        R+  +    + ++ A R++  EER +  
Sbjct: 324 DDRGPPQRPKLNLKPRSTPKEDDSSASTSQSTRAASIFGGAKPVDTAAREREVEERLQKE 383

Query: 540 KEE 542
           +E+
Sbjct: 384 QEK 386



 Score = 34.3 bits (77), Expect = 0.32
 Identities = 45/211 (21%), Positives = 77/211 (36%), Gaps = 28/211 (13%)

Query: 388 RDEEWGGHSPRSPRGWDQEPAREQAGGGWRARRPRARSVDALDDLTPP------------ 435
           RD+++ G   R    +D+   R      W +R   +R     DD  PP            
Sbjct: 287 RDDDYRGGGDRYEDRYDRRDDRS-----WSSRDDYSRDDYRRDDRGPPQRPKLNLKPRST 341

Query: 436 --------STAESGSRSPTSNGGRSRAYMPPRSRSRDDLYDQDDSRDFPRSRDPHYDDFR 487
                   ST++S +R+ +  GG        R R  ++   ++  +   R  D    + R
Sbjct: 342 PKEDDSSASTSQS-TRAASIFGGAKPVDTAAREREVEERLQKEQEK-LQRQLDEPKLERR 399

Query: 488 SRERPPADPRSHHHRTRDPRDNGSRSGDLPYDGRLLEEAVRKKGSEERRRPHKEEEEEAY 547
            RER P+  RS   + R+    GS S            A R++  +        +EE+ +
Sbjct: 400 PRERHPSW-RSEETQERERSRTGSESSQTGTSTTSSRNARRRESEKSLENETLNKEEDCH 458

Query: 548 YPPAPPPYSETDSQASRERRLKKNLALSRES 578
            P + PP  +   +       K+N  + R S
Sbjct: 459 SPTSKPPKPDQPLKVMPAPPPKENAWVKRSS 489


>gi|154354983 regulating synaptic membrane exocytosis 2 isoform a
           [Homo sapiens]
          Length = 1349

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 46/185 (24%), Positives = 73/185 (39%), Gaps = 9/185 (4%)

Query: 398 RSPRGWDQEPAREQAGGGWRARRPRARSVDALDDLTPPSTAESGSRSPTSNGGRSRAYMP 457
           + P G    PA E++      R+   ++   +        A    RSP+ +  ++R Y  
Sbjct: 190 QGPSGDLSVPAVEKSRSHGLTRQHSIKNGSGVKHHIASDIASDRKRSPSVSRDQNRRYDQ 249

Query: 458 PRSRSRDDLYDQDDSRDFPRSRDPHYDDFRSRERPPADPRSHHHRTRDPRDNGSR-SGDL 516
              R     Y   D+   PRS    Y D RS+  P     S H   RD      R S + 
Sbjct: 250 REEREEYSQYATSDTA-MPRSPSD-YADRRSQHEPQFYEDSDHLSYRDSNRRSHRHSKEY 307

Query: 517 PYDGRLLE---EAVRKKGSEERRRPHKEEEEEAYYPPAPPPYSE---TDSQASRERRLKK 570
             D   +E   E  R++  EE +  ++ +   A YP  P PY E     ++ SR R  ++
Sbjct: 308 IVDDEDVESRDEYERQRREEEYQSRYRSDPNLARYPVKPQPYEEQMRIHAEVSRARHERR 367

Query: 571 NLALS 575
           +  +S
Sbjct: 368 HSDVS 372


>gi|116089325 splicing factor, arginine/serine-rich 12 isoform a
           [Homo sapiens]
          Length = 624

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 40/158 (25%), Positives = 63/158 (39%), Gaps = 21/158 (13%)

Query: 398 RSPRGWDQEPAREQAGGGWRARRPRARSVDALDDLTPPSTAESGSRSPTSNGGRSRAYMP 457
           + P    Q  A+E      R R  ++    A++  +  S    G RS +    +SR+   
Sbjct: 262 KPPEMTPQAAAKELEEVMKRVREAQSFISAAIEPESGKSNERKGGRSRSHTRSKSRSSSK 321

Query: 458 PRSR---------SRDDLYDQDDSRDFPRSRDPHYDDFRSRERPPADPRSH-HHRTRDPR 507
             SR         SR     +   +D  RS+ PH    +SRER  +  RSH   + +D R
Sbjct: 322 SHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTR 381

Query: 508 DNGSRSGDLPYDGRLLEEAVRKKGSEERRRPHKEEEEE 545
           +               +E V++K  E+ R   KE E+E
Sbjct: 382 EKIKE-----------KERVKEKDREKEREREKEREKE 408



 Score = 38.1 bits (87), Expect = 0.022
 Identities = 38/160 (23%), Positives = 59/160 (36%), Gaps = 17/160 (10%)

Query: 417 RARRPRARSVDALDDLTPPSTAESGSRSPTSNGGRSRAYMPPRSRSRDDLYDQDDSRDFP 476
           R  R R+ S D   D       +   +       R R     + + R    D+D  R+  
Sbjct: 365 RKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKD 424

Query: 477 RSRDPHYDDFRSRERPPADPRSHHHRTRDPRDNGSRSGDLPYDGRLLEEAVRKKGSEERR 536
           R +D   D  R RE+        H + RD      +  +   D     E  R K  +E+R
Sbjct: 425 REKDKEKDREREREK-------EHEKDRD------KEKEKEQDKEKEREKDRSKEIDEKR 471

Query: 537 RPHKEEEEEAYYPPAPPPYSETDSQASRERRLKKNLALSR 576
           +  K+       PP     S     +SRERR +++ + SR
Sbjct: 472 KKDKKSRT----PPRSYNASRRSRSSSRERRRRRSRSSSR 507


>gi|21040255 splicing factor, arginine/serine-rich 12 isoform b
           [Homo sapiens]
          Length = 508

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 40/158 (25%), Positives = 63/158 (39%), Gaps = 21/158 (13%)

Query: 398 RSPRGWDQEPAREQAGGGWRARRPRARSVDALDDLTPPSTAESGSRSPTSNGGRSRAYMP 457
           + P    Q  A+E      R R  ++    A++  +  S    G RS +    +SR+   
Sbjct: 146 KPPEMTPQAAAKELEEVMKRVREAQSFISAAIEPESGKSNERKGGRSRSHTRSKSRSSSK 205

Query: 458 PRSR---------SRDDLYDQDDSRDFPRSRDPHYDDFRSRERPPADPRSH-HHRTRDPR 507
             SR         SR     +   +D  RS+ PH    +SRER  +  RSH   + +D R
Sbjct: 206 SHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTR 265

Query: 508 DNGSRSGDLPYDGRLLEEAVRKKGSEERRRPHKEEEEE 545
           +               +E V++K  E+ R   KE E+E
Sbjct: 266 EKIKE-----------KERVKEKDREKEREREKEREKE 292



 Score = 38.1 bits (87), Expect = 0.022
 Identities = 38/160 (23%), Positives = 59/160 (36%), Gaps = 17/160 (10%)

Query: 417 RARRPRARSVDALDDLTPPSTAESGSRSPTSNGGRSRAYMPPRSRSRDDLYDQDDSRDFP 476
           R  R R+ S D   D       +   +       R R     + + R    D+D  R+  
Sbjct: 249 RKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKD 308

Query: 477 RSRDPHYDDFRSRERPPADPRSHHHRTRDPRDNGSRSGDLPYDGRLLEEAVRKKGSEERR 536
           R +D   D  R RE+        H + RD      +  +   D     E  R K  +E+R
Sbjct: 309 REKDKEKDREREREK-------EHEKDRD------KEKEKEQDKEKEREKDRSKEIDEKR 355

Query: 537 RPHKEEEEEAYYPPAPPPYSETDSQASRERRLKKNLALSR 576
           +  K+       PP     S     +SRERR +++ + SR
Sbjct: 356 KKDKKSRT----PPRSYNASRRSRSSSRERRRRRSRSSSR 391


>gi|186700623 Rab-like GTP-binding protein 1 isoform 1 [Homo
           sapiens]
          Length = 729

 Score = 40.4 bits (93), Expect = 0.005
 Identities = 90/344 (26%), Positives = 119/344 (34%), Gaps = 53/344 (15%)

Query: 264 SPAK--TPPPPAMIPM--GPA-YNGYPGGYPGD-VDRS-----SSAGGQGSYVPLLRDTD 312
           SPA    PPPP  +P   GPA         P D +DRS     + A  +          D
Sbjct: 365 SPATEAAPPPPEPVPAAEGPATVQSVEDFVPDDRLDRSFLEDTTPARDEKKVGAKAAQQD 424

Query: 313 SSVASEVRSGYRIQASQQDDSMRVLYYMEKELANFDPSRPGPPSGRVERAMSEVTSLHED 372
           S    E   G  + A  QDD          +L +     P  P+G V  +     S  E+
Sbjct: 425 SDSDGEALGGNPMVAGFQDDV---------DLEDQPRGSPPLPAGPVP-SQDITLSSEEE 474

Query: 373 DWRSRPSRGPALTPIRDEE----WGGHSPRSPRGWDQEPAREQAG---GGWRARR-PRAR 424
              + P++GPA  P +  E    W       PR     P R  A    GG   R  P  R
Sbjct: 475 AEVAAPTKGPAPAPQQCSEPETKWSSIPASKPRR-GTAPTRTAAPPWPGGVSVRTGPEKR 533

Query: 425 SVDALDDLTPPSTAESGSRSPTSNGGRSRAYMPPRSRSRDDLYDQ--DDSR---DFPRSR 479
           S         P   E  S S +   G   A M        D   +  D  R   DFP   
Sbjct: 534 SSTRPPAEMEPGKGEQASSSESDPEGPIAAQMLSFVMDDPDFESEGSDTQRRADDFPVRD 593

Query: 480 DPHYDDFRSRERPPADPRSHHHRTRDPRDNGSRSGDLPYDGRLLEEAVRKKGSEE----- 534
           DP   D    +  PA+P       + P        D    G  LEEA  K+ SEE     
Sbjct: 594 DP--SDVTDEDEGPAEPPPP---PKLPLPAFRLKNDSDLFGLGLEEAGPKESSEEGKEGK 648

Query: 535 --------RRRPHKEEEEEAYYPPAPPPYSETDSQASRERRLKK 570
                   +++  KEEEE+A    +    S+   +   ERR ++
Sbjct: 649 TPSKEKKKKKKKGKEEEEKAAKKKSKHKKSKDKEEGKEERRRRQ 692


>gi|42518065 tight junction protein 2 (zona occludens 2) isoform 2
           [Homo sapiens]
          Length = 1043

 Score = 40.4 bits (93), Expect = 0.005
 Identities = 57/232 (24%), Positives = 83/232 (35%), Gaps = 34/232 (14%)

Query: 318 EVRSGYRIQASQQDDSMRVLYYMEKELANFDPSRPGPPSGRVERAMSEVTSLHEDDWRSR 377
           +V   + +Q  ++   +  +             +  PP  + +RA   +       +RS 
Sbjct: 95  DVLHSFAVQQLRKSGKVAAIVVKRPRKVQVAALQASPPLDQDDRAFEVMDEFDGRSFRSG 154

Query: 378 PSRGPALTPIRDEEWGGHSPRSPRGWDQEPAREQAGGGWRAR-------RPRARSVDALD 430
            S    L          H  RS R W+  P R +     R+R       R R RS++   
Sbjct: 155 YSERSRLN--------SHGGRS-RSWEDSPERGRPHERARSRERDLSRDRSRGRSLERGL 205

Query: 431 DLTPPSTAESGSRSPTSNGGRSRAYMPPRSRSRDDL----YDQDDSRDFPRSRDPHYDDF 486
           D     T +  SR  +   G    + P R R RD       DQD  R + R+ DP Y+  
Sbjct: 206 DQDHARTRDR-SRGRSLERGLDHDFGPSRDRDRDRSRGRSIDQDYERAYHRAYDPDYERA 264

Query: 487 RSRERPPADPRSHHHRTRDPRDNGSRSGDLPYDGRLLEEAVRKKGSEERRRP 538
            S E        H  R+R PR   SRS + P+         R    E R RP
Sbjct: 265 YSPEYRRG--ARHDARSRGPR---SRSREHPHS--------RSPSPEPRGRP 303


>gi|42518070 tight junction protein 2 (zona occludens 2) isoform 1
           [Homo sapiens]
          Length = 1190

 Score = 40.4 bits (93), Expect = 0.005
 Identities = 57/232 (24%), Positives = 83/232 (35%), Gaps = 34/232 (14%)

Query: 318 EVRSGYRIQASQQDDSMRVLYYMEKELANFDPSRPGPPSGRVERAMSEVTSLHEDDWRSR 377
           +V   + +Q  ++   +  +             +  PP  + +RA   +       +RS 
Sbjct: 95  DVLHSFAVQQLRKSGKVAAIVVKRPRKVQVAALQASPPLDQDDRAFEVMDEFDGRSFRSG 154

Query: 378 PSRGPALTPIRDEEWGGHSPRSPRGWDQEPAREQAGGGWRAR-------RPRARSVDALD 430
            S    L          H  RS R W+  P R +     R+R       R R RS++   
Sbjct: 155 YSERSRLN--------SHGGRS-RSWEDSPERGRPHERARSRERDLSRDRSRGRSLERGL 205

Query: 431 DLTPPSTAESGSRSPTSNGGRSRAYMPPRSRSRDDL----YDQDDSRDFPRSRDPHYDDF 486
           D     T +  SR  +   G    + P R R RD       DQD  R + R+ DP Y+  
Sbjct: 206 DQDHARTRDR-SRGRSLERGLDHDFGPSRDRDRDRSRGRSIDQDYERAYHRAYDPDYERA 264

Query: 487 RSRERPPADPRSHHHRTRDPRDNGSRSGDLPYDGRLLEEAVRKKGSEERRRP 538
            S E        H  R+R PR   SRS + P+         R    E R RP
Sbjct: 265 YSPEYRRG--ARHDARSRGPR---SRSREHPHS--------RSPSPEPRGRP 303


>gi|32699028 V-set and immunoglobulin domain containing 1 [Homo
           sapiens]
          Length = 387

 Score = 40.0 bits (92), Expect = 0.006
 Identities = 30/103 (29%), Positives = 46/103 (44%), Gaps = 6/103 (5%)

Query: 173 VRVVATKQGNAVTLGDYYQGRRITIT---GNADLTFDQTAWGDSGVYYCSVVSAQDLQGN 229
           + +  ++ G AV +G +    RIT +   GNA +T       DSG+Y C V +  D  G 
Sbjct: 70  ISIYFSQGGQAVAIGQFKD--RITGSNDPGNASITISHMQPADSGIYICDVNNPPDFLGQ 127

Query: 230 NEAYAELIVLVYAAGK-AATSGVPSIYAPSTYAHLSPAKTPPP 271
           N+    + VLV  +    +  G P      + + LS   TP P
Sbjct: 128 NQGILNVSVLVKPSKPLCSVQGRPETGHTISLSCLSALGTPSP 170


>gi|38146113 arginine/serine-rich coiled-coil 2 isoform b [Homo
           sapiens]
          Length = 375

 Score = 39.7 bits (91), Expect = 0.008
 Identities = 50/164 (30%), Positives = 67/164 (40%), Gaps = 47/164 (28%)

Query: 440 SGSRSPTSNGGRSRAYMPPRSRSRDDLYDQDDSRDFPRSRDPHYDDFRSRERPPADPRS- 498
           S  RS + +  R R +   RSRSR+    +  SR+  +SR       RSRER  +  RS 
Sbjct: 61  SRGRSHSRSRSRERRH---RSRSRERKKSRSRSRERKKSRS------RSRERKKSRSRSR 111

Query: 499 ---------------HHHRTRDPRDNGSRSGDLPYDGRLLEEAVRKKGSEERRRPHKEEE 543
                          H HRTR      SRS D            RKK  E+ RR  +   
Sbjct: 112 ERKRRIRSRSRSRSRHRHRTRSRSRTRSRSRD------------RKKRIEKPRRFSRSLS 159

Query: 544 EEAYYPPAPPPY----SETDSQASRERRLK--KNLALSRESLVV 581
                 P+PPP+    +  D+Q +  RRL+  K L   RE  +V
Sbjct: 160 R----TPSPPPFRGRNTAMDAQEALARRLERAKKLQEQREKEMV 199



 Score = 29.6 bits (65), Expect = 8.0
 Identities = 26/119 (21%), Positives = 49/119 (41%), Gaps = 3/119 (2%)

Query: 461 RSRDDLYDQDDSRDFPRSRDPHYDDFRSRERPPADPRSHHHRTRDPRDNGSRSGDLPYDG 520
           + R+ L   ++  D  + ++      RS  R  +  R H  R+R+ + + SRS +     
Sbjct: 38  KGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSR 97

Query: 521 RLLEE--AVRKKGSEERRRPHKEEEEEAYYPPAPPPYSETDSQA-SRERRLKKNLALSR 576
               E    R +  E +RR        + +       S T S++  R++R++K    SR
Sbjct: 98  SRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSR 156


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.314    0.132    0.406 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 27,477,210
Number of Sequences: 37866
Number of extensions: 1539139
Number of successful extensions: 8412
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 65
Number of HSP's successfully gapped in prelim test: 298
Number of HSP's that attempted gapping in prelim test: 7229
Number of HSP's gapped (non-prelim): 1023
length of query: 581
length of database: 18,247,518
effective HSP length: 108
effective length of query: 473
effective length of database: 14,157,990
effective search space: 6696729270
effective search space used: 6696729270
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.