Guide to the Human Genome
Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Search of human proteins with 45593130

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|45593130 guanine nucleotide binding protein-like 3 isoform 1
[Homo sapiens]
         (549 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|45593130 guanine nucleotide binding protein-like 3 isoform 1 ...  1088   0.0  
gi|45643129 guanine nucleotide binding protein-like 3 isoform 2 ...  1066   0.0  
gi|45643127 guanine nucleotide binding protein-like 3 isoform 2 ...  1066   0.0  
gi|9506611 guanine nucleotide binding protein-like 3 (nucleolar)...   282   6e-76
gi|7019419 guanine nucleotide binding protein-like 2 (nucleolar)...   171   1e-42
gi|93277113 GTP_binding protein [Homo sapiens]                         61   2e-09
gi|223029424 large subunit GTPase 1 [Homo sapiens]                     59   2e-08
gi|38788319 guanine nucleotide binding protein-like 1 [Homo sapi...    51   3e-06
gi|154354979 myosin X [Homo sapiens]                                   48   3e-05
gi|88759339 aster-associated protein [Homo sapiens]                    47   6e-05
gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]            46   8e-05
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]            45   1e-04
gi|153945728 microtubule-associated protein 1B [Homo sapiens]          45   2e-04
gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]     44   5e-04
gi|29244924 chromodomain helicase DNA binding protein 6 [Homo sa...    44   5e-04
gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]             44   5e-04
gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ...    42   0.001
gi|30581135 structural maintenance of chromosomes 1A [Homo sapiens]    42   0.001
gi|148746195 trichohyalin [Homo sapiens]                               42   0.001
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa...    42   0.002
gi|4503179 oral-facial-digital syndrome 1 [Homo sapiens]               41   0.002
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa...    41   0.003
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]                       41   0.003
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa...    41   0.003
gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ...    41   0.003
gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [...    41   0.003
gi|24308223 hypothetical protein LOC57577 [Homo sapiens]               41   0.003
gi|119709834 castor homolog 1, zinc finger isoform a [Homo sapiens]    40   0.006
gi|4759100 splicing factor, arginine/serine-rich 11 [Homo sapiens]     40   0.007
gi|148806928 hypothetical protein LOC57482 [Homo sapiens]              40   0.007

>gi|45593130 guanine nucleotide binding protein-like 3 isoform 1
           [Homo sapiens]
          Length = 549

 Score = 1088 bits (2815), Expect = 0.0
 Identities = 549/549 (100%), Positives = 549/549 (100%)

Query: 1   MKRPKLKKASKRMTCHKRYKIQKKVREHHRKLRKEAKKRGHKKPRKDPGVPNSAPFKEAL 60
           MKRPKLKKASKRMTCHKRYKIQKKVREHHRKLRKEAKKRGHKKPRKDPGVPNSAPFKEAL
Sbjct: 1   MKRPKLKKASKRMTCHKRYKIQKKVREHHRKLRKEAKKRGHKKPRKDPGVPNSAPFKEAL 60

Query: 61  LREAELRKQRLEELKQQQKLDRQKELEKKRKLETNPDIKPSNVEPMEKEFGLCKTENKAK 120
           LREAELRKQRLEELKQQQKLDRQKELEKKRKLETNPDIKPSNVEPMEKEFGLCKTENKAK
Sbjct: 61  LREAELRKQRLEELKQQQKLDRQKELEKKRKLETNPDIKPSNVEPMEKEFGLCKTENKAK 120

Query: 121 SGKQNSKKLYCQELKKVIEASDVVLEVLDARDPLGCRCPQVEEAIVQSGQKKLVLILNKS 180
           SGKQNSKKLYCQELKKVIEASDVVLEVLDARDPLGCRCPQVEEAIVQSGQKKLVLILNKS
Sbjct: 121 SGKQNSKKLYCQELKKVIEASDVVLEVLDARDPLGCRCPQVEEAIVQSGQKKLVLILNKS 180

Query: 181 DLVPKENLESWLNYLKKELPTVVFRASTKPKDKGKITKRVKAKKNAAPFRSEVCFGKEGL 240
           DLVPKENLESWLNYLKKELPTVVFRASTKPKDKGKITKRVKAKKNAAPFRSEVCFGKEGL
Sbjct: 181 DLVPKENLESWLNYLKKELPTVVFRASTKPKDKGKITKRVKAKKNAAPFRSEVCFGKEGL 240

Query: 241 WKLLGGFQETCSKAIRVGVIGFPNVGKSSIINSLKQEQMCNVGVSMGLTRSMQVVPLDKQ 300
           WKLLGGFQETCSKAIRVGVIGFPNVGKSSIINSLKQEQMCNVGVSMGLTRSMQVVPLDKQ
Sbjct: 241 WKLLGGFQETCSKAIRVGVIGFPNVGKSSIINSLKQEQMCNVGVSMGLTRSMQVVPLDKQ 300

Query: 301 ITIIDSPSFIVSPLNSSSALALRSPASIEVVKPMEAASAILSQADARQVVLKYTVPGYRN 360
           ITIIDSPSFIVSPLNSSSALALRSPASIEVVKPMEAASAILSQADARQVVLKYTVPGYRN
Sbjct: 301 ITIIDSPSFIVSPLNSSSALALRSPASIEVVKPMEAASAILSQADARQVVLKYTVPGYRN 360

Query: 361 SLEFFTVLAQRRGMHQKGGIPNVEGAAKLLWSEWTGASLAYYCHPPTSWTPPPYFNESIV 420
           SLEFFTVLAQRRGMHQKGGIPNVEGAAKLLWSEWTGASLAYYCHPPTSWTPPPYFNESIV
Sbjct: 361 SLEFFTVLAQRRGMHQKGGIPNVEGAAKLLWSEWTGASLAYYCHPPTSWTPPPYFNESIV 420

Query: 421 VDMKSGFNLEELEKNNAQSIRAIKGPHLANSILFQSSGLTNGIIEEKDIHEELPKRKERK 480
           VDMKSGFNLEELEKNNAQSIRAIKGPHLANSILFQSSGLTNGIIEEKDIHEELPKRKERK
Sbjct: 421 VDMKSGFNLEELEKNNAQSIRAIKGPHLANSILFQSSGLTNGIIEEKDIHEELPKRKERK 480

Query: 481 QEEREDDKDSDQETVDEEVDENSSGMFAAEETGEALSEETTAGEQSTRSFILDKIIEEDD 540
           QEEREDDKDSDQETVDEEVDENSSGMFAAEETGEALSEETTAGEQSTRSFILDKIIEEDD
Sbjct: 481 QEEREDDKDSDQETVDEEVDENSSGMFAAEETGEALSEETTAGEQSTRSFILDKIIEEDD 540

Query: 541 AYDFSTDYV 549
           AYDFSTDYV
Sbjct: 541 AYDFSTDYV 549


>gi|45643129 guanine nucleotide binding protein-like 3 isoform 2
           [Homo sapiens]
          Length = 537

 Score = 1066 bits (2756), Expect = 0.0
 Identities = 537/537 (100%), Positives = 537/537 (100%)

Query: 13  MTCHKRYKIQKKVREHHRKLRKEAKKRGHKKPRKDPGVPNSAPFKEALLREAELRKQRLE 72
           MTCHKRYKIQKKVREHHRKLRKEAKKRGHKKPRKDPGVPNSAPFKEALLREAELRKQRLE
Sbjct: 1   MTCHKRYKIQKKVREHHRKLRKEAKKRGHKKPRKDPGVPNSAPFKEALLREAELRKQRLE 60

Query: 73  ELKQQQKLDRQKELEKKRKLETNPDIKPSNVEPMEKEFGLCKTENKAKSGKQNSKKLYCQ 132
           ELKQQQKLDRQKELEKKRKLETNPDIKPSNVEPMEKEFGLCKTENKAKSGKQNSKKLYCQ
Sbjct: 61  ELKQQQKLDRQKELEKKRKLETNPDIKPSNVEPMEKEFGLCKTENKAKSGKQNSKKLYCQ 120

Query: 133 ELKKVIEASDVVLEVLDARDPLGCRCPQVEEAIVQSGQKKLVLILNKSDLVPKENLESWL 192
           ELKKVIEASDVVLEVLDARDPLGCRCPQVEEAIVQSGQKKLVLILNKSDLVPKENLESWL
Sbjct: 121 ELKKVIEASDVVLEVLDARDPLGCRCPQVEEAIVQSGQKKLVLILNKSDLVPKENLESWL 180

Query: 193 NYLKKELPTVVFRASTKPKDKGKITKRVKAKKNAAPFRSEVCFGKEGLWKLLGGFQETCS 252
           NYLKKELPTVVFRASTKPKDKGKITKRVKAKKNAAPFRSEVCFGKEGLWKLLGGFQETCS
Sbjct: 181 NYLKKELPTVVFRASTKPKDKGKITKRVKAKKNAAPFRSEVCFGKEGLWKLLGGFQETCS 240

Query: 253 KAIRVGVIGFPNVGKSSIINSLKQEQMCNVGVSMGLTRSMQVVPLDKQITIIDSPSFIVS 312
           KAIRVGVIGFPNVGKSSIINSLKQEQMCNVGVSMGLTRSMQVVPLDKQITIIDSPSFIVS
Sbjct: 241 KAIRVGVIGFPNVGKSSIINSLKQEQMCNVGVSMGLTRSMQVVPLDKQITIIDSPSFIVS 300

Query: 313 PLNSSSALALRSPASIEVVKPMEAASAILSQADARQVVLKYTVPGYRNSLEFFTVLAQRR 372
           PLNSSSALALRSPASIEVVKPMEAASAILSQADARQVVLKYTVPGYRNSLEFFTVLAQRR
Sbjct: 301 PLNSSSALALRSPASIEVVKPMEAASAILSQADARQVVLKYTVPGYRNSLEFFTVLAQRR 360

Query: 373 GMHQKGGIPNVEGAAKLLWSEWTGASLAYYCHPPTSWTPPPYFNESIVVDMKSGFNLEEL 432
           GMHQKGGIPNVEGAAKLLWSEWTGASLAYYCHPPTSWTPPPYFNESIVVDMKSGFNLEEL
Sbjct: 361 GMHQKGGIPNVEGAAKLLWSEWTGASLAYYCHPPTSWTPPPYFNESIVVDMKSGFNLEEL 420

Query: 433 EKNNAQSIRAIKGPHLANSILFQSSGLTNGIIEEKDIHEELPKRKERKQEEREDDKDSDQ 492
           EKNNAQSIRAIKGPHLANSILFQSSGLTNGIIEEKDIHEELPKRKERKQEEREDDKDSDQ
Sbjct: 421 EKNNAQSIRAIKGPHLANSILFQSSGLTNGIIEEKDIHEELPKRKERKQEEREDDKDSDQ 480

Query: 493 ETVDEEVDENSSGMFAAEETGEALSEETTAGEQSTRSFILDKIIEEDDAYDFSTDYV 549
           ETVDEEVDENSSGMFAAEETGEALSEETTAGEQSTRSFILDKIIEEDDAYDFSTDYV
Sbjct: 481 ETVDEEVDENSSGMFAAEETGEALSEETTAGEQSTRSFILDKIIEEDDAYDFSTDYV 537


>gi|45643127 guanine nucleotide binding protein-like 3 isoform 2
           [Homo sapiens]
          Length = 537

 Score = 1066 bits (2756), Expect = 0.0
 Identities = 537/537 (100%), Positives = 537/537 (100%)

Query: 13  MTCHKRYKIQKKVREHHRKLRKEAKKRGHKKPRKDPGVPNSAPFKEALLREAELRKQRLE 72
           MTCHKRYKIQKKVREHHRKLRKEAKKRGHKKPRKDPGVPNSAPFKEALLREAELRKQRLE
Sbjct: 1   MTCHKRYKIQKKVREHHRKLRKEAKKRGHKKPRKDPGVPNSAPFKEALLREAELRKQRLE 60

Query: 73  ELKQQQKLDRQKELEKKRKLETNPDIKPSNVEPMEKEFGLCKTENKAKSGKQNSKKLYCQ 132
           ELKQQQKLDRQKELEKKRKLETNPDIKPSNVEPMEKEFGLCKTENKAKSGKQNSKKLYCQ
Sbjct: 61  ELKQQQKLDRQKELEKKRKLETNPDIKPSNVEPMEKEFGLCKTENKAKSGKQNSKKLYCQ 120

Query: 133 ELKKVIEASDVVLEVLDARDPLGCRCPQVEEAIVQSGQKKLVLILNKSDLVPKENLESWL 192
           ELKKVIEASDVVLEVLDARDPLGCRCPQVEEAIVQSGQKKLVLILNKSDLVPKENLESWL
Sbjct: 121 ELKKVIEASDVVLEVLDARDPLGCRCPQVEEAIVQSGQKKLVLILNKSDLVPKENLESWL 180

Query: 193 NYLKKELPTVVFRASTKPKDKGKITKRVKAKKNAAPFRSEVCFGKEGLWKLLGGFQETCS 252
           NYLKKELPTVVFRASTKPKDKGKITKRVKAKKNAAPFRSEVCFGKEGLWKLLGGFQETCS
Sbjct: 181 NYLKKELPTVVFRASTKPKDKGKITKRVKAKKNAAPFRSEVCFGKEGLWKLLGGFQETCS 240

Query: 253 KAIRVGVIGFPNVGKSSIINSLKQEQMCNVGVSMGLTRSMQVVPLDKQITIIDSPSFIVS 312
           KAIRVGVIGFPNVGKSSIINSLKQEQMCNVGVSMGLTRSMQVVPLDKQITIIDSPSFIVS
Sbjct: 241 KAIRVGVIGFPNVGKSSIINSLKQEQMCNVGVSMGLTRSMQVVPLDKQITIIDSPSFIVS 300

Query: 313 PLNSSSALALRSPASIEVVKPMEAASAILSQADARQVVLKYTVPGYRNSLEFFTVLAQRR 372
           PLNSSSALALRSPASIEVVKPMEAASAILSQADARQVVLKYTVPGYRNSLEFFTVLAQRR
Sbjct: 301 PLNSSSALALRSPASIEVVKPMEAASAILSQADARQVVLKYTVPGYRNSLEFFTVLAQRR 360

Query: 373 GMHQKGGIPNVEGAAKLLWSEWTGASLAYYCHPPTSWTPPPYFNESIVVDMKSGFNLEEL 432
           GMHQKGGIPNVEGAAKLLWSEWTGASLAYYCHPPTSWTPPPYFNESIVVDMKSGFNLEEL
Sbjct: 361 GMHQKGGIPNVEGAAKLLWSEWTGASLAYYCHPPTSWTPPPYFNESIVVDMKSGFNLEEL 420

Query: 433 EKNNAQSIRAIKGPHLANSILFQSSGLTNGIIEEKDIHEELPKRKERKQEEREDDKDSDQ 492
           EKNNAQSIRAIKGPHLANSILFQSSGLTNGIIEEKDIHEELPKRKERKQEEREDDKDSDQ
Sbjct: 421 EKNNAQSIRAIKGPHLANSILFQSSGLTNGIIEEKDIHEELPKRKERKQEEREDDKDSDQ 480

Query: 493 ETVDEEVDENSSGMFAAEETGEALSEETTAGEQSTRSFILDKIIEEDDAYDFSTDYV 549
           ETVDEEVDENSSGMFAAEETGEALSEETTAGEQSTRSFILDKIIEEDDAYDFSTDYV
Sbjct: 481 ETVDEEVDENSSGMFAAEETGEALSEETTAGEQSTRSFILDKIIEEDDAYDFSTDYV 537


>gi|9506611 guanine nucleotide binding protein-like 3
           (nucleolar)-like [Homo sapiens]
          Length = 582

 Score =  282 bits (721), Expect = 6e-76
 Identities = 162/425 (38%), Positives = 256/425 (60%), Gaps = 11/425 (2%)

Query: 29  HRKLR----KEAKKRGHKKPRKDPGVPNSAPFKEALLREAELRKQRLEELKQQQKLDRQK 84
           H+K+     + AK+ G K   K P  P+     +   REAEL+K+ +EE++++Q+  R++
Sbjct: 18  HKKISWPYPQPAKQNGKKATSKVPSAPHFVHPNDHANREAELKKKWVEEMREKQQAAREQ 77

Query: 85  ELEKKRKLETN-PDIKPSNVEPMEKEFGLCKTENKAKSGKQNSKKLYCQELKKVIEASDV 143
           E +K+R +E+   D+     E   KE  L +     +   + ++K Y +E +KV+E SDV
Sbjct: 78  ERQKRRTIESYCQDVLRRQEEFEHKEEVLQELNMFPQLDDEATRKAYYKEFRKVVEYSDV 137

Query: 144 VLEVLDARDPLGCRCPQVEEAIVQS-GQKKLVLILNKSDLVPKENLESWLNYLKKELPTV 202
           +LEVLDARDPLGCRC Q+EEA++++ G KKLVL+LNK DLVPKE +E WL+YL+ ELPTV
Sbjct: 138 ILEVLDARDPLGCRCFQMEEAVLRAQGNKKLVLVLNKIDLVPKEVVEKWLDYLRNELPTV 197

Query: 203 VFRASTKPKDKGKITKRVKAKK-NAAPFRSEVCFGKEGLWKLLGGFQET--CSKAIRVGV 259
            F+AST+ + K      V   + + +  +S+ CFG E L ++LG +         IRVGV
Sbjct: 198 AFKASTQHQVKNLNRCSVPVDQASESLLKSKACFGAENLMRVLGNYCRLGEVRTHIRVGV 257

Query: 260 IGFPNVGKSSIINSLKQEQMCNVGVSMGLTRSMQVVPLDKQITIIDSPSFIVSPLNSSSA 319
           +G PNVGKSS+INSLK+ + C+VG   G+T+ MQ V LDK I ++D+P  +  P NS   
Sbjct: 258 VGLPNVGKSSLINSLKRSRACSVGAVPGITKFMQEVYLDKFIRLLDAPGIVPGP-NSEVG 316

Query: 320 LALRSPASIE-VVKPMEAASAILSQADARQVVLKYTVPGYRNSLEFFTVLAQRRGMHQKG 378
             LR+   ++ +  P+     IL + +  ++   Y V G++ +  F T +A R G  +KG
Sbjct: 317 TILRNCVHVQKLADPVTPVETILQRCNLEEISNYYGVSGFQTTEHFLTAVAHRLGKKKKG 376

Query: 379 GIPNVEGAAKLLWSEWTGASLAYYCHPPTSWTPPPYFNESIVVDMKSGFNLEELEKNNAQ 438
           G+ + E AAK + ++W    +++Y  PP + T P + +  IV +M   F++E+ E+ N  
Sbjct: 377 GLYSQEQAAKAVLADWVSGKISFYIPPPATHTLPTHLSAEIVKEMTEVFDIEDTEQANED 436

Query: 439 SIRAI 443
           ++  +
Sbjct: 437 TMECL 441


>gi|7019419 guanine nucleotide binding protein-like 2 (nucleolar)
           [Homo sapiens]
          Length = 731

 Score =  171 bits (434), Expect = 1e-42
 Identities = 122/421 (28%), Positives = 204/421 (48%), Gaps = 54/421 (12%)

Query: 114 KTENKAKSGKQNSKKLYCQELKKVIEASDVVLEVLDARDPLGCRCPQVEEAIVQSGQ-KK 172
           + E + +  K+   K    EL KVI++SDVV++VLDARDP+G R P +E  + +    K 
Sbjct: 190 RNEAQEEIYKKGQSKRIWGELYKVIDSSDVVVQVLDARDPMGTRSPHIETYLKKEKPWKH 249

Query: 173 LVLILNKSDLVPKENLESWLNYLKKELPTVVFRAS-TKPKDKGKITKRVKAKKNAAPFRS 231
           L+ +LNK DLVP    + W+  L ++ PT+ F AS T P  KG   + ++          
Sbjct: 250 LIFVLNKCDLVPTWATKRWVAVLSQDYPTLAFHASLTNPFGKGAFIQLLRQ--------- 300

Query: 232 EVCFGKEGLWKLLGGFQETCSKAIRVGVIGFPNVGKSSIINSLKQEQMCNVGVSMGLTRS 291
              FGK            T  K I VG IG+PNVGKSS+IN+L+ +++CNV    G T+ 
Sbjct: 301 ---FGK----------LHTDKKQISVGFIGYPNVGKSSVINTLRSKKVCNVAPIAGETKV 347

Query: 292 MQVVPLDKQITIIDSPSFIVSPLNSSSALALRSPASIEVVK-PMEAASAILSQADARQVV 350
            Q + L ++I +ID P  +    +S + + L+    +E +K P +   A+L +A    + 
Sbjct: 348 WQYITLMRRIFLIDCPGVVYPSEDSETDIVLKGVVQVEKIKSPEDHIGAVLERAKPEYIS 407

Query: 351 LKYTVPGYRNSLEFFTVLAQRRGMHQKGGIPNVEGAAKLLWSEWTGASLAYYCHPPTS-- 408
             Y +  + N+ +F   LA R G   KGG P+++   K++ ++W    + ++  PP +  
Sbjct: 408 KTYKIDSWENAEDFLEKLAFRTGKLLKGGEPDLQTVGKMVLNDWQRGRIPFFVKPPNAEP 467

Query: 409 -WTPPPYFNESIVVDMKSGFN------------------LEELEKNN--------AQSIR 441
              P    + S+ V  ++  N                   EE E+N+         Q + 
Sbjct: 468 LVAPQLLPSSSLEVVPEAAQNNPGEEVTETAGEGSESIIKEETEENSHCDANTEMQQILT 527

Query: 442 AIKGPHLANSILFQSSGLTNGIIEEKDIHEELPKRKERKQEEREDDKDSDQETVDEEVDE 501
            ++      +++ Q SG     +E  D+ EEL    + ++EE+E  +D  +E+  E  +E
Sbjct: 528 RVRQNFGKINVVPQFSGDDLVPVEVSDLEEELESFSDEEEEEQEQQRDDAEESSSEPEEE 587

Query: 502 N 502
           N
Sbjct: 588 N 588


>gi|93277113 GTP_binding protein [Homo sapiens]
          Length = 334

 Score = 61.2 bits (147), Expect = 2e-09
 Identities = 57/194 (29%), Positives = 95/194 (48%), Gaps = 29/194 (14%)

Query: 132 QELKKVIEASDVVLEVLDARDPLGCRCPQVEEAIVQSGQKKLVLILNKSDLVPKENLESW 191
           ++++  ++  D ++EV DAR PL  R P  +E +   G K  +L+LNK DL      +  
Sbjct: 40  KKMQSSLKLVDCIIEVHDARIPLSGRNPLFQETL---GLKPHLLVLNKMDLADLTEQQKI 96

Query: 192 LNYLKKE-LPTVVFRASTKPKDKGKITKRVKAKKNAAPFRSEVCFGKEGLWKLLGGFQET 250
           + +L+ E L  V+F    K ++  +I   V         RS     KE L        E 
Sbjct: 97  MQHLEGEGLKNVIFTNCVKDENVKQIIPMVTELIG----RSHRYHRKENL--------EY 144

Query: 251 CSKAIRVGVIGFPNVGKSSIINSLKQEQM-----CNVGVSMGLTRS-MQVVPLDKQ--IT 302
           C     + VIG PNVGKSS+INSL+++ +       VG   G+TR+ M  + + ++  + 
Sbjct: 145 C-----IMVIGVPNVGKSSLINSLRRQHLRKGKATRVGGEPGITRAVMSKIQVSERPLMF 199

Query: 303 IIDSPSFIVSPLNS 316
           ++D+P  +   + S
Sbjct: 200 LLDTPGVLAPRIES 213


>gi|223029424 large subunit GTPase 1 [Homo sapiens]
          Length = 658

 Score = 58.5 bits (140), Expect = 2e-08
 Identities = 40/134 (29%), Positives = 69/134 (51%), Gaps = 22/134 (16%)

Query: 72  EELKQQQKLDRQKELEKKRKLETNPDIKPSNVEPMEKEFGLCKTENKAKSGKQNSKKLYC 131
           EELKQ +K      LE +R+L    + +   + P E+                     + 
Sbjct: 126 EELKQAEK---DNFLEWRRQLVRLEEEQKLILTPFERNLD------------------FW 164

Query: 132 QELKKVIEASDVVLEVLDARDPLGCRCPQVEEAIVQ-SGQKKLVLILNKSDLVPKENLES 190
           ++L +VIE SD+V++++DAR+PL  RC  +E  + +    K+ V+++NK+DL+  E   +
Sbjct: 165 RQLWRVIERSDIVVQIVDARNPLLFRCEDLECYVKEMDANKENVILINKADLLTAEQRSA 224

Query: 191 WLNYLKKELPTVVF 204
           W  Y +KE   V+F
Sbjct: 225 WAMYFEKEDVKVIF 238



 Score = 55.1 bits (131), Expect = 2e-07
 Identities = 47/225 (20%), Positives = 98/225 (43%), Gaps = 18/225 (8%)

Query: 255 IRVGVIGFPNVGKSSIINSLKQEQMCNVGVSMGLTRSMQVVPLDKQITIIDSPSFIVSPL 314
           + VG++G+PNVGKSS IN++   +  +V  + G T+  Q + ++  + + D P  ++   
Sbjct: 387 LTVGLVGYPNVGKSSTINTIMGNKKVSVSATPGHTKHFQTLYVEPGLCLCDCPGLVMPSF 446

Query: 315 NSSSA-LALRSPASIEVVKPMEAASAILSQADARQVV-----LKYTVPGYRN-------S 361
            S+ A +       I+ ++      +++ Q   R V+     +    P           S
Sbjct: 447 VSTKAEMTCSGILPIDQMRDHVPPVSLVCQNIPRHVLEATYGINIITPREDEDPHRPPTS 506

Query: 362 LEFFTVLAQRRGMHQKGGIPNVEGAAKLLWSEWTGASLAYYCHPPTSWTPPPYFNESIVV 421
            E  T     RG     G P+   +A+ +  ++    L  YCHPP    P  + ++   +
Sbjct: 507 EELLTAYGYMRGFMTAHGQPDQPRSARYILKDYVSGKL-LYCHPPPGRDPVTFQHQHQRL 565

Query: 422 DMKSGFNLEELEKNNAQSIRAIKGPHLANSILFQSS---GLTNGI 463
            +++  N +E++    ++ +A +  ++ +   F       LT G+
Sbjct: 566 -LENKMNSDEIKMQLGRNKKAKQIENIVDKTFFHQENVRALTKGV 609


>gi|38788319 guanine nucleotide binding protein-like 1 [Homo
           sapiens]
          Length = 607

 Score = 50.8 bits (120), Expect = 3e-06
 Identities = 69/281 (24%), Positives = 103/281 (36%), Gaps = 53/281 (18%)

Query: 255 IRVGVIGFPNVGKSSIINSLKQEQMCNVGVSMGLTRSMQVVPLDKQITIIDSPSFIVSPL 314
           + +G +GFPNVGKSS+IN L   ++ +V  + G TR  Q   L   + + D P  I   L
Sbjct: 361 VTIGCVGFPNVGKSSLINGLVGRKVVSVSRTPGHTRYFQTYFLTPSVKLCDCPGLIFPSL 420

Query: 315 NSSSALALRSPASIEVVKPMEAASAILSQADARQVVLKYTVPGYRN--------SLEFFT 366
                  L     I  ++    A   L+     Q +L    P   +        + +   
Sbjct: 421 LPRQLQVLAGIYPIAQIQEPYTAVGYLASRIPVQALLHLRHPEAEDPSAEHPWCAWDICE 480

Query: 367 VLAQRRGMH-QKGGIPNVEGAAKLLWSEWTGASLAYYCHPP------TSWTPPPYFNESI 419
             A++RG    K    +V  AA  L        L+   HPP       +W   P   E +
Sbjct: 481 AWAEKRGYKTAKAARNDVYRAANSLLRLAVDGRLSLCFHPPGYSEQKGTWESHPETTELV 540

Query: 420 VVDMKSGFNLEELEKNNAQSIRAIKGPHLANSILFQSSGLTNGIIEEKDIHEELPKRKER 479
           V+  + G                              +G      EE++  EEL    E 
Sbjct: 541 VLQGRVG-----------------------------PAG-----DEEEEEEEELSSSCE- 565

Query: 480 KQEEREDDKDSDQE-TVDEEVDENSSGMFAAEETGEALSEE 519
             EE E+D+D+D+E   DEE   ++ G   A     AL  E
Sbjct: 566 --EEGEEDRDADEEGEGDEETPTSAPGSSLAGRNPYALLGE 604


>gi|154354979 myosin X [Homo sapiens]
          Length = 2058

 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 44/159 (27%), Positives = 73/159 (45%), Gaps = 29/159 (18%)

Query: 7   KKASKRMTCHKRYKIQKKVREHHRKLRKEAKKRGHKKPRKDPGVPNSAPFKEALLREAEL 66
           ++  +++   KR + +KK +E   K ++E ++R  ++ R                REAEL
Sbjct: 805 RRVYRQLLAEKREQEEKKKQEEEEKKKREEEERERERER----------------REAEL 848

Query: 67  RKQRLEELKQQQKLD----RQKELEKKRKLETNPDIKP-SNVEPMEKEFGLCKTENKAKS 121
           R Q+ EE ++QQ+L+     QKE E  R+LE   + K    +  +EKE      E+  + 
Sbjct: 849 RAQQEEETRKQQELEALQKSQKEAELTRELEKQKENKQVEEILRLEKEI-----EDLQRM 903

Query: 122 GKQNSKKLYCQELKKVIEASDVVLEVLDARDPLGCRCPQ 160
            +Q    L    L+K+ E  D  L  L+      CR  Q
Sbjct: 904 KEQQELSLTEASLQKLQERRDQELRRLEEE---ACRAAQ 939


>gi|88759339 aster-associated protein [Homo sapiens]
          Length = 647

 Score = 46.6 bits (109), Expect = 6e-05
 Identities = 39/137 (28%), Positives = 71/137 (51%), Gaps = 7/137 (5%)

Query: 7   KKASKRMTCHKRYKIQKKVREHHRKLRKEAKKRGHKKPRKDPGVPNSAPFKEALLREAEL 66
           KKA+KR      ++  K ++E   K +  AKKR  +K +K     N+A   EAL    + 
Sbjct: 461 KKAAKREEALASFEAWKAMKEKEAK-KIAAKKRLEEKNKKKTEEENAARKGEALQAFEKW 519

Query: 67  RKQRLEELKQQQKLDRQKELEKKRK-LETNPDIKPSNVEPMEKEFGLCKTENKAKSGKQN 125
           +++++E LK++ + +R+ E  KK+K  ET  + K  N+  +EK       E K    KQ 
Sbjct: 520 KEKKMEYLKEKNRKEREYERAKKQKEEETVAEKKKDNLTAVEK-----WNEKKEAFFKQK 574

Query: 126 SKKLYCQELKKVIEASD 142
            K+   ++ K+ ++ ++
Sbjct: 575 EKEKINEKRKEELKRAE 591


>gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 275

 Score = 46.2 bits (108), Expect = 8e-05
 Identities = 35/130 (26%), Positives = 65/130 (50%), Gaps = 6/130 (4%)

Query: 2   KRPKLKKASKRMTCHKRYKIQKKVREHHRKLRKEAKKRGHKKPRKDPGVPNSAPFKEALL 61
           KR + KK  K+    +R K +++ R+   K RKE +++  +K +K+         K+   
Sbjct: 55  KRERGKKEKKKRKKRERGKERERKRKEREKQRKERREKERRKRKKEK---KKRERKQRGR 111

Query: 62  REAELRKQRLE---ELKQQQKLDRQKELEKKRKLETNPDIKPSNVEPMEKEFGLCKTENK 118
           RE + +K+R E   E KQ+++  R+K  +KKR+ E   + +    E   K+    + E K
Sbjct: 112 RERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKK 171

Query: 119 AKSGKQNSKK 128
            +  ++  KK
Sbjct: 172 RERNRKERKK 181



 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 31/111 (27%), Positives = 56/111 (50%), Gaps = 3/111 (2%)

Query: 2   KRPKLKKASKRMTCHKRYKIQKKVREHHRKLRKEAKKRGHKKPRKDPGVPNSAPFKEALL 61
           KR K KK  +R    +R + +KK R+   +  K+ ++R  KK RK          KE   
Sbjct: 96  KRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERGK 155

Query: 62  REAELRKQRLEEL---KQQQKLDRQKELEKKRKLETNPDIKPSNVEPMEKE 109
           RE + +K++ EE    +++ + +R+KE E+K + E   + K    +  E++
Sbjct: 156 RERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKERK 206



 Score = 43.5 bits (101), Expect = 5e-04
 Identities = 35/127 (27%), Positives = 62/127 (48%), Gaps = 6/127 (4%)

Query: 2   KRPKLKKASKRMTCHKRYKIQKKVREHHRKLRKEAKKRGHKKPRKDPGVPNSAPFKEALL 61
           +R K +K  +     KR K +KK RE  ++ R+E KK   KK RK+    N    +    
Sbjct: 81  EREKQRKERREKERRKRKK-EKKKRERKQRGRRERKK---KKERKERERENKQ--RRERK 134

Query: 62  REAELRKQRLEELKQQQKLDRQKELEKKRKLETNPDIKPSNVEPMEKEFGLCKTENKAKS 121
           R+   +K+R +E K++++  +++   KKRK E     +  N +  +KE    +   + K 
Sbjct: 135 RKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKE 194

Query: 122 GKQNSKK 128
            K+  +K
Sbjct: 195 RKKERRK 201



 Score = 43.1 bits (100), Expect = 7e-04
 Identities = 38/135 (28%), Positives = 63/135 (46%), Gaps = 9/135 (6%)

Query: 2   KRPKLKKASKRMTCHKRYKIQKKVREHHRKLRKEAKKRGHKKPRKDPGVPNSAPFKEALL 61
           KR + K+  +     KR + +K+ +E   K R++ KK   K+ RK  G       KE   
Sbjct: 68  KRERGKERER-----KRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKE 122

Query: 62  REAELRKQRLEELKQQQKLDRQKELEKKRKLETNPDIKPSNVEPMEKEFGLCKTENKAKS 121
           RE E +++R  + K+++K  R+KE    RK E     +    +  +KE    K E   K 
Sbjct: 123 RERENKQRRERKRKKRRKKKRRKE----RKREKERGKRERKRKKRKKEEREKKRERNRKE 178

Query: 122 GKQNSKKLYCQELKK 136
            K+  ++   +E KK
Sbjct: 179 RKKERERKERRERKK 193



 Score = 43.1 bits (100), Expect = 7e-04
 Identities = 26/107 (24%), Positives = 52/107 (48%)

Query: 2   KRPKLKKASKRMTCHKRYKIQKKVREHHRKLRKEAKKRGHKKPRKDPGVPNSAPFKEALL 61
           +R + ++ +K+    KR K +KK R   RK  KE  KR  K+ ++          +    
Sbjct: 119 ERKERERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKE 178

Query: 62  REAELRKQRLEELKQQQKLDRQKELEKKRKLETNPDIKPSNVEPMEK 108
           R+ E  ++   E K+++K +R+K+ E+K+  +T+         P+ +
Sbjct: 179 RKKERERKERRERKKERKKERRKKKERKKDRKTDRQTDSQVFRPLRE 225



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 32/122 (26%), Positives = 57/122 (46%), Gaps = 2/122 (1%)

Query: 7   KKASKRMTCHKRYKIQKKVREHHRKLRKEAKKRGHKKPRKDPGVPNSAPFKEALLREAEL 66
           KK  +     KR + +++ RE  +K +K+ KKR   K R+          KE   RE E 
Sbjct: 37  KKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKER--REKER 94

Query: 67  RKQRLEELKQQQKLDRQKELEKKRKLETNPDIKPSNVEPMEKEFGLCKTENKAKSGKQNS 126
           RK++ E+ K+++K   ++E +KK++ +          E   K+    K   + K  K+  
Sbjct: 95  RKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKERG 154

Query: 127 KK 128
           K+
Sbjct: 155 KR 156



 Score = 39.7 bits (91), Expect = 0.007
 Identities = 31/128 (24%), Positives = 63/128 (49%), Gaps = 14/128 (10%)

Query: 1   MKRPKLKKASKRMTCHKRYKIQKKVREHHRKLRKEAKKRGHKKPRKDPGVPNSAPFKEAL 60
           + +P  ++ S+R    +  + +K+ RE  RK R+  KK   K+ +++ G       KE  
Sbjct: 25  ISKPCTQRESERKKERREREKRKREREKERK-RERGKKEKKKRKKRERG-------KERE 76

Query: 61  LREAELRKQRLEELKQQQKLDRQKELEKKRKLETNPDIKPSNVEPMEKEFGLCKTENKAK 120
            +  E  KQR +E +++++  R+KE +K+ + +     +    E  E+E      ENK +
Sbjct: 77  RKRKEREKQR-KERREKERRKRKKEKKKRERKQRGRRERKKKKERKERE-----RENKQR 130

Query: 121 SGKQNSKK 128
             ++  K+
Sbjct: 131 RERKRKKR 138



 Score = 33.1 bits (74), Expect = 0.68
 Identities = 32/125 (25%), Positives = 54/125 (43%), Gaps = 25/125 (20%)

Query: 5   KLKKASKRMTCHKRYKIQKKVREHHRKLRKEAKKRGHKKPRKDPGVPNSAPFKEALLREA 64
           KL    + ++C    K   +     +K R+E +KR  +                   RE 
Sbjct: 12  KLNTELQMVSCSHISKPCTQRESERKKERREREKRKRE-------------------REK 52

Query: 65  ELRKQR-LEELKQQQKLDRQKELEKKRKLETNPDIKPSNVEPMEKEFGLCKTENKAKSGK 123
           E +++R  +E K+++K +R KE E+KRK     + +    E  EKE    K E K +  K
Sbjct: 53  ERKRERGKKEKKKRKKRERGKERERKRK-----EREKQRKERREKERRKRKKEKKKRERK 107

Query: 124 QNSKK 128
           Q  ++
Sbjct: 108 QRGRR 112


>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 245

 Score = 45.4 bits (106), Expect = 1e-04
 Identities = 30/127 (23%), Positives = 59/127 (46%)

Query: 2   KRPKLKKASKRMTCHKRYKIQKKVREHHRKLRKEAKKRGHKKPRKDPGVPNSAPFKEALL 61
           +R + K+  +R    KR + +K+ +   +K  +E KKR  +K  K+         KE   
Sbjct: 63  RREREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKE 122

Query: 62  REAELRKQRLEELKQQQKLDRQKELEKKRKLETNPDIKPSNVEPMEKEFGLCKTENKAKS 121
           R    ++ +  E K+++K + +KE E+K++       +    +   K+ G  + E K K 
Sbjct: 123 RGRTSKEGKERERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKEKE 182

Query: 122 GKQNSKK 128
            K+  K+
Sbjct: 183 RKERKKR 189



 Score = 43.1 bits (100), Expect = 7e-04
 Identities = 32/128 (25%), Positives = 60/128 (46%), Gaps = 1/128 (0%)

Query: 2   KRPKLKKASKRMTCHKRYKIQKKVREHHRKLRKEAKKRGHKKPRKDPGVPNSAPFKEALL 61
           +R K ++  +     ++ K +KK ++   +  KE K+R  K+ RK          KE   
Sbjct: 96  ERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEERE 155

Query: 62  REAELRKQRLEELKQQ-QKLDRQKELEKKRKLETNPDIKPSNVEPMEKEFGLCKTENKAK 120
           +E E ++++  E KQ  +K + +KE E+K + +   + K    E   KE    K E K K
Sbjct: 156 KERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKK 215

Query: 121 SGKQNSKK 128
             ++  ++
Sbjct: 216 EERKKERQ 223



 Score = 42.0 bits (97), Expect = 0.001
 Identities = 31/133 (23%), Positives = 59/133 (44%), Gaps = 6/133 (4%)

Query: 2   KRPKLKKASKRMTCHKRYKIQKKVREHHRKLRKEAKKRGH------KKPRKDPGVPNSAP 55
           K+ + KK  +     +R K  K+  E  ++ +KE K+RG       ++ RK+        
Sbjct: 86  KKGERKKEERERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERK 145

Query: 56  FKEALLREAELRKQRLEELKQQQKLDRQKELEKKRKLETNPDIKPSNVEPMEKEFGLCKT 115
            +E    E E  ++R E  K+++K   +KE E+K K       +  N +  +KE    + 
Sbjct: 146 ERERKKEEREKERERKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKER 205

Query: 116 ENKAKSGKQNSKK 128
             + K  K+  ++
Sbjct: 206 RERKKERKKKEER 218



 Score = 37.4 bits (85), Expect = 0.036
 Identities = 29/122 (23%), Positives = 61/122 (50%), Gaps = 7/122 (5%)

Query: 7   KKASKRMTCHKRYKIQKKVREHHRKLRKEAKKRGHKKPRKDPGVPNSAPFKEALLREAEL 66
           K+  +R    +R + ++K RE  ++ R++ ++R  +K R+   V      KE   +E E 
Sbjct: 128 KEGKERERKEERKREERKERERKKEEREKERERKERKKRERKQVGE----KEEERKEKE- 182

Query: 67  RKQRLEELKQQQKLDRQKELEKKRKLETNPDIKPSNVEPMEKEFGLCKTENKAKSGKQNS 126
           RK+R +  +++ + +R+KE E+K + E   + K       E++        + + GK+  
Sbjct: 183 RKERKK--RERNRKERKKERERKERRERKKERKKKEERKKERQKDRQTNWREKERGKRER 240

Query: 127 KK 128
           K+
Sbjct: 241 KE 242



 Score = 35.4 bits (80), Expect = 0.14
 Identities = 29/107 (27%), Positives = 48/107 (44%), Gaps = 26/107 (24%)

Query: 22  QKKVREHHRKLRKEAKKRGHKKPRKDPGVPNSAPFKEALLREAELRKQRLEELKQQQKLD 81
           Q ++RE  R++  E +K G K+                  RE+E +K+R E  K      
Sbjct: 35  QSEIREREREI--ETRKEGKKE------------------RESERKKERREREK------ 68

Query: 82  RQKELEKKRKLETNPDIKPSNVEPMEKEFGLCKTENKAKSGKQNSKK 128
           R++E EK+RK E     K    +  E+E    + E + K G++  K+
Sbjct: 69  RKREREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEKEKR 115



 Score = 31.6 bits (70), Expect = 2.0
 Identities = 32/110 (29%), Positives = 55/110 (50%), Gaps = 15/110 (13%)

Query: 23  KKVREHHRKLRK---EAKKRGHKKPRK-DPGVPNSAPFKEALLREAELRKQRLEELKQQQ 78
           KK RE  RK  +   E +KR  +K RK + G       ++   RE + R+ R +E K+ +
Sbjct: 52  KKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRR-REKENKEGE 110

Query: 79  KLDRQKELEKKRKLETNPDIKPSNVEPMEKEFGLCKTENKAKSGKQNSKK 128
           + +++K+ EKK +  T+ + K       E+E    K E K +  K+  +K
Sbjct: 111 EKEKRKKKEKKERGRTSKEGK-------ERE---RKEERKREERKERERK 150



 Score = 31.2 bits (69), Expect = 2.6
 Identities = 27/92 (29%), Positives = 47/92 (51%), Gaps = 22/92 (23%)

Query: 2   KRPKLKKASKRMTCHKRYKIQKKVREHHRKLRKEAKKR--GHKKPRKDPGVPNSAPFKEA 59
           K  + K+  KR    +R ++ +K  E   K RKE KKR    K+ +K+            
Sbjct: 156 KERERKERKKR----ERKQVGEKEEERKEKERKERKKRERNRKERKKE------------ 199

Query: 60  LLREAELRKQRLEELKQQQKLDRQKELEKKRK 91
             RE + R++R +E K+++  +R+KE +K R+
Sbjct: 200 --RERKERRERKKERKKKE--ERKKERQKDRQ 227


>gi|153945728 microtubule-associated protein 1B [Homo sapiens]
          Length = 2468

 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 55/224 (24%), Positives = 90/224 (40%), Gaps = 49/224 (21%)

Query: 5   KLKKASKRMTCHKRYKIQKKVREHHRKLRKEAKKRGHKKPRKDPGVP-NSAPFKEALLRE 63
           K + A K+ T  K    ++K  +   K++ E KK   +KP+K+     +  P K+     
Sbjct: 617 KAEVAEKQATDVKPKAAKEKTVKKETKVKPEDKKEEKEKPKKEVAKKEDKTPIKKE---- 672

Query: 64  AELRKQRLEELKQQQKLDRQKELEKKRKLETNPDIKPSNVEPMEKEFGLCKTENKAKSGK 123
               K + EE+K++ K + +KE +K+ K E   +  P  V+   K     K E K    +
Sbjct: 673 ---EKPKKEEVKKEVKKEIKKEEKKEPKKEVKKETPPKEVKKEVK-----KEEKKEVKKE 724

Query: 124 QNSKKLYCQELKKVIEASDVVLEVLDARDPLGCRCPQVEEAIVQSGQKKLVLILNKSDLV 183
           +   K   ++L K  + S   L        L  + P+ EE++             K D V
Sbjct: 725 EKEPKKEIKKLPKDAKKSSTPLSEAKKPAALKPKVPKKEESV-------------KKDSV 771

Query: 184 PKENLESWLNYLKKELPTVVFRASTKPKDKGKITKRVKAKKNAA 227
                                 A+ KPK+KGKI K +K +  AA
Sbjct: 772 ----------------------AAGKPKEKGKI-KVIKKEGKAA 792



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 39/146 (26%), Positives = 73/146 (50%), Gaps = 12/146 (8%)

Query: 2   KRPKLKKASKRMTCHKRYKIQKKVREHHRKLRKEAKKRGHKKPRKDPGVPNSAPFKEALL 61
           ++PK + A K      + + + K  E  ++++KE KK   K+P+K+  V    P KE   
Sbjct: 654 EKPKKEVAKKEDKTPIKKEEKPKKEEVKKEVKKEIKKEEKKEPKKE--VKKETPPKEV-- 709

Query: 62  REAELRKQRLEELKQQQKLDRQ--KELEKKRKLETNP---DIKPSNVEPM--EKEFGLCK 114
            + E++K+  +E+K+++K  ++  K+L K  K  + P     KP+ ++P   +KE  + K
Sbjct: 710 -KKEVKKEEKKEVKKEEKEPKKEIKKLPKDAKKSSTPLSEAKKPAALKPKVPKKEESVKK 768

Query: 115 TENKAKSGKQNSKKLYCQELKKVIEA 140
               A   K+  K    ++  K  EA
Sbjct: 769 DSVAAGKPKEKGKIKVIKKEGKAAEA 794



 Score = 32.0 bits (71), Expect = 1.5
 Identities = 43/209 (20%), Positives = 90/209 (43%), Gaps = 28/209 (13%)

Query: 31  KLRKEAKKRGHKKPRKDPGVPNSAPFKEALLREAELRKQRLEELKQQQKLDRQKELEKKR 90
           KL++ A  R   KP   P +P+ +  KE+     E+ K  +  +++  K++ ++++  K+
Sbjct: 534 KLKQRADSRESLKPAAKP-LPSKSVRKESKEETPEVTK--VNHVEKPPKVESKEKVMVKK 590

Query: 91  ----KLETNPDIK----PSNVEPMEKEFGLCK---TENKAKSGKQNS----KKLYCQELK 135
               K ET P +     PS  EP   +  + +   T+ K K+ K+ +     K+  ++ K
Sbjct: 591 DKPIKTETKPSVTEKEVPSKEEPSPVKAEVAEKQATDVKPKAAKEKTVKKETKVKPEDKK 650

Query: 136 KVIEASDVVLEVLDARDPLGCRCPQVEEAIVQSGQKKLVLILNKSDLVPKENLESWLNYL 195
           +  E     +   + + P+       +E + +  +K+          + KE  +     +
Sbjct: 651 EEKEKPKKEVAKKEDKTPIKKEEKPKKEEVKKEVKKE----------IKKEEKKEPKKEV 700

Query: 196 KKELPTVVFRASTKPKDKGKITKRVKAKK 224
           KKE P    +   K ++K ++ K  K  K
Sbjct: 701 KKETPPKEVKKEVKKEEKKEVKKEEKEPK 729



 Score = 31.6 bits (70), Expect = 2.0
 Identities = 27/110 (24%), Positives = 50/110 (45%), Gaps = 13/110 (11%)

Query: 21   IQKKVREHHRKLRKEAKKRGHKKPRKDPGV--PNSAPFKEALLREAELRKQRLEELKQQQ 78
            ++K ++E  +  +   K +     +K  G   P +A  K A L+E+  +  R+   K+++
Sbjct: 2235 LKKDLKEKTKTKKPGTKTKSSSPVKKSDGKSKPLAASPKPAGLKESSDKVSRVASPKKKE 2294

Query: 79   KLDRQKELEKKRKLETNPDIKPSNVEPMEKEFGLCKTENKAKSGKQNSKK 128
             +      EK  K  T P++K +  E  +KE     T+N A +    S K
Sbjct: 2295 SV------EKAAKPTTTPEVKAARGEEKDKE-----TKNAANASASKSAK 2333


>gi|32483416 neurofilament, heavy polypeptide 200kDa [Homo sapiens]
          Length = 1020

 Score = 43.5 bits (101), Expect = 5e-04
 Identities = 49/201 (24%), Positives = 81/201 (40%), Gaps = 15/201 (7%)

Query: 24   KVREHHRKLRKEAKKRGHKKPRKDPGVPNSAPFKEALLREAELRKQRLEELKQQQKLDRQ 83
            KV+E  +K  +E      K   K       AP KEA   + E +K+   E  ++ K++ +
Sbjct: 834  KVKEPPKKAEEEKAPATPKTEEKKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAK 893

Query: 84   K-ELEKKRKLETNPDIKPSNVEPMEKEFGLCKTENKAKSGKQNSKKLYCQELKKVIEASD 142
            K E E K+K+ T     P+ VE  E      K + K +  K+       +E  K  E  +
Sbjct: 894  KEEAEDKKKVPTPEKEAPAKVEVKED----AKPKEKTEVAKKEPDDAKAKEPSKPAEKKE 949

Query: 143  VVLEVLDARDPLGCRCPQVEEAIVQSGQKKLVLILNKSDLVPKENLESWLNYLKKELPTV 202
               E  D ++    + P+ E+   ++  K+    L+K    PK          K E  + 
Sbjct: 950  AAPEKKDTKEE-KAKKPE-EKPKTEAKAKEDDKTLSKEPSKPKAE--------KAEKSSS 999

Query: 203  VFRASTKPKDKGKITKRVKAK 223
              +  +KP +K    K  K K
Sbjct: 1000 TDQKDSKPPEKATEDKAAKGK 1020



 Score = 37.4 bits (85), Expect = 0.036
 Identities = 37/130 (28%), Positives = 57/130 (43%), Gaps = 9/130 (6%)

Query: 7   KKASKRMTCHKRYKIQKKVREHH-------RKLRKEAKKRGHKKPRKDPGVPNSAPFKEA 59
           KK SK+    K+   + KV E         ++ + EAKK   +  +K P     AP K  
Sbjct: 856 KKDSKKEEAPKKEAPKPKVEEKKEPAVEKPKESKVEAKKEEAEDKKKVPTPEKEAPAKVE 915

Query: 60  LLREAELRKQRLEELKQQQKLDRQKELEKK-RKLETNPDIKPSNVEPMEKEFGLCKTENK 118
           +  +A+  K++ E  K++    + KE  K   K E  P+ K +  E  +K     KTE K
Sbjct: 916 VKEDAK-PKEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAK 974

Query: 119 AKSGKQNSKK 128
           AK   +   K
Sbjct: 975 AKEDDKTLSK 984



 Score = 30.0 bits (66), Expect = 5.7
 Identities = 27/103 (26%), Positives = 43/103 (41%), Gaps = 7/103 (6%)

Query: 23   KKVREHHRKLRKEAKKRGHKKP-RKDPGVPNSAPFKEALLREAELRKQRLEELKQQQK-L 80
            K+  E  +K   +AK +   KP  K    P     KE   ++ E + +   + K+  K L
Sbjct: 923  KEKTEVAKKEPDDAKAKEPSKPAEKKEAAPEKKDTKEEKAKKPEEKPKTEAKAKEDDKTL 982

Query: 81   DRQKELEKKRKLETNPDIKPSNVEPMEKEFGLCKTENKAKSGK 123
             ++    K  K E +      + +P EK      TE+KA  GK
Sbjct: 983  SKEPSKPKAEKAEKSSSTDQKDSKPPEKA-----TEDKAAKGK 1020


>gi|29244924 chromodomain helicase DNA binding protein 6 [Homo
           sapiens]
          Length = 2715

 Score = 43.5 bits (101), Expect = 5e-04
 Identities = 46/162 (28%), Positives = 74/162 (45%), Gaps = 24/162 (14%)

Query: 3   RPKLKKASKRMTCHKRYKIQKKVREHHRKLRKEAKKRGHKKPRKDPGVPNSAPFKEALLR 62
           +PK K+  K     ++ K  KK +EH    +K+  K+  +KPR+  G    A  K +   
Sbjct: 117 KPKRKREPKEPKEPRKAKEPKKAKEHKEPKQKDGAKKA-RKPREASGT-KEAKEKRSCTD 174

Query: 63  EAELRKQRLEELKQQQKLDRQKELEKKRKLETNPDIKPSNVEPMEKEFGLC--------- 113
            A   K R +  K+Q     +K+ + KRK ET        VE +E + GL          
Sbjct: 175 SAARTKSR-KASKEQGPTPVEKKKKGKRKSET-------TVESLELDQGLTNPSLRSPEE 226

Query: 114 KTEN----KAKSGKQNSKKLYCQELK-KVIEASDVVLEVLDA 150
            TE+    K +SG+Q  ++ Y ++L  KV++     + VL A
Sbjct: 227 STESTDSQKRRSGRQVKRRKYNEDLDFKVVDDDGETIAVLGA 268


>gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]
          Length = 2817

 Score = 43.5 bits (101), Expect = 5e-04
 Identities = 36/161 (22%), Positives = 81/161 (50%), Gaps = 17/161 (10%)

Query: 5   KLKKASKRMTCHKRYKIQKKVREHHRKLRKEAKKRGHKKPRKDPGVPNSAPFKEALLREA 64
           KLK+  +++   ++    +++RE  R+  +E +K   K+  ++         KE   RE 
Sbjct: 484 KLKRLDEKLGILEKQPSPEEIREREREKEREREKELEKEQEQERE-------KE---REK 533

Query: 65  ELRKQRLEELKQQQKLDRQKELEKKRKLETNPDIKPSNVEPMEKEFGLCKTENKAKSGKQ 124
           +  +Q+ +E + +++ ++Q+E+EK+RK E   +++       EKE  L K + + K  + 
Sbjct: 534 DRERQQEKEKELEKEQEKQREMEKERKQEKEKELE----RQKEKEKELQKMKEQEKECEL 589

Query: 125 NSKKLYCQELKKVIEASDVVLEVLDARDPLGCRCPQVEEAI 165
             ++   ++L++ IE  +  LE +  +      C + EE +
Sbjct: 590 EKER---EKLEEKIEPREPNLEPMVEKQESENSCNKEEEPV 627



 Score = 38.5 bits (88), Expect = 0.016
 Identities = 35/152 (23%), Positives = 73/152 (48%), Gaps = 7/152 (4%)

Query: 20  KIQKKVREHHRKLRKEAKKR-GHKKPRKDP--GVPNSAPFKEALLREAELRK--QRLEEL 74
           + +K+  E  R++ ++ K     K  R D   G+    P  E + RE E  K  +R +EL
Sbjct: 461 RARKRREEEERRMEEQRKAACAEKLKRLDEKLGILEKQPSPEEI-REREREKEREREKEL 519

Query: 75  KQQQKLDRQKELEKKRKLETNPDIKPSNVEPMEKEFGLCKTENKAKS-GKQNSKKLYCQE 133
           +++Q+ +R+KE EK R+ +   + +    +  ++E    + + K K   +Q  K+   Q+
Sbjct: 520 EKEQEQEREKEREKDRERQQEKEKELEKEQEKQREMEKERKQEKEKELERQKEKEKELQK 579

Query: 134 LKKVIEASDVVLEVLDARDPLGCRCPQVEEAI 165
           +K+  +  ++  E     + +  R P +E  +
Sbjct: 580 MKEQEKECELEKEREKLEEKIEPREPNLEPMV 611



 Score = 38.1 bits (87), Expect = 0.021
 Identities = 32/133 (24%), Positives = 62/133 (46%), Gaps = 24/133 (18%)

Query: 18  RYKIQKKVREHHRKLRKEAKKRGHKKPRKDPG--VPNSAPFKEALLREAELRKQRLEELK 75
           R + ++K RE  ++L KE ++   K+  KD           ++   ++ E+ K+R +E  
Sbjct: 505 REREREKEREREKELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQREMEKERKQE-- 562

Query: 76  QQQKLDRQKELEK-----------------KRKLETNPDIKPSNVEPM---EKEFGLCKT 115
           ++++L+RQKE EK                 + KLE   + +  N+EPM   ++    C  
Sbjct: 563 KEKELERQKEKEKELQKMKEQEKECELEKEREKLEEKIEPREPNLEPMVEKQESENSCNK 622

Query: 116 ENKAKSGKQNSKK 128
           E +    +Q+S +
Sbjct: 623 EEEPVFTRQDSNR 635



 Score = 37.0 bits (84), Expect = 0.047
 Identities = 28/111 (25%), Positives = 57/111 (51%), Gaps = 2/111 (1%)

Query: 27  EHHRKLRKEAKKRGHKKPRKDPGVPNSAPFKEAL-LREAELRKQRLEELKQQQKLDRQKE 85
           E  RK R+E ++R  ++ RK           E L + E +   + + E +++++ +R+KE
Sbjct: 460 ERARKRREEEERRMEEQ-RKAACAEKLKRLDEKLGILEKQPSPEEIREREREKEREREKE 518

Query: 86  LEKKRKLETNPDIKPSNVEPMEKEFGLCKTENKAKSGKQNSKKLYCQELKK 136
           LEK+++ E   + +       EKE  L K + K +  ++  K+   +EL++
Sbjct: 519 LEKEQEQEREKEREKDRERQQEKEKELEKEQEKQREMEKERKQEKEKELER 569



 Score = 30.8 bits (68), Expect = 3.4
 Identities = 14/40 (35%), Positives = 25/40 (62%)

Query: 462 GIIEEKDIHEELPKRKERKQEEREDDKDSDQETVDEEVDE 501
           GI+E++   EE+ +R+  K+ ERE + + +QE   E+  E
Sbjct: 493 GILEKQPSPEEIREREREKEREREKELEKEQEQEREKERE 532


>gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo
           sapiens]
          Length = 600

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 29/96 (30%), Positives = 49/96 (51%), Gaps = 16/96 (16%)

Query: 3   RPKLKKASKRMTCHKRYKIQKKVREHHRKL-RKEAKKRGHKKPRKDPGVPNSAPFKEALL 61
           R + +K  +R T  KR +  ++ RE  RK  R+  ++R  ++ RK               
Sbjct: 272 RDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRK--------------- 316

Query: 62  REAELRKQRLEELKQQQKLDRQKELEKKRKLETNPD 97
           RE E  ++R  E +++ + DR+KE E+KRK +T  D
Sbjct: 317 RERERERERERERQRETERDREKERERKRKRQTEMD 352



 Score = 32.7 bits (73), Expect = 0.88
 Identities = 27/124 (21%), Positives = 64/124 (51%), Gaps = 12/124 (9%)

Query: 7   KKASKRMTCHKRYKIQKKVREHHRKLRKEAKKRGHK-KPRKDPGVPNSAPFKEALLREAE 65
           +K  +R T  +R + ++K R   ++  +E ++ G + + R+  G       +    R+AE
Sbjct: 102 EKERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQR-----ERERQRDAE 156

Query: 66  LRKQRLEELKQQQKLDRQKELEKKRKLETNPDIKPSNVEPMEKEFGLCKTENK-AKSGKQ 124
             ++R  + ++Q++ +R ++  K+R+ E N   +       EKE    KTE++ ++ G++
Sbjct: 157 KERERQTDRERQRQTERNRQ--KEREREKNRQERRERERQREKE---NKTEDRHSERGRE 211

Query: 125 NSKK 128
             ++
Sbjct: 212 RERE 215



 Score = 32.3 bits (72), Expect = 1.2
 Identities = 22/94 (23%), Positives = 48/94 (51%), Gaps = 1/94 (1%)

Query: 17  KRYKIQKKVREHHRKLRKEAKKRGHK-KPRKDPGVPNSAPFKEALLREAELRKQRLEELK 75
           KR +  +  RE +R+  +E +++  + + R+      SA  +E   R+ +  +Q+  E +
Sbjct: 344 KRKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQ 403

Query: 76  QQQKLDRQKELEKKRKLETNPDIKPSNVEPMEKE 109
            ++  D Q+E EK+R+ E + + +       E+E
Sbjct: 404 TEKDRDGQRETEKQREREKDRESERGRERGRERE 437



 Score = 30.0 bits (66), Expect = 5.7
 Identities = 20/103 (19%), Positives = 47/103 (45%), Gaps = 3/103 (2%)

Query: 7   KKASKRMTCHKRYKIQKKVREHHRKLRKEAKKRGHKKPRKDPGVPNSAPFKEALLREAEL 66
           +K  +R T  +R +  ++ R+  R+  K  ++R  ++ +++          E   R  E 
Sbjct: 156 EKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSE---RGRER 212

Query: 67  RKQRLEELKQQQKLDRQKELEKKRKLETNPDIKPSNVEPMEKE 109
            ++R  E + ++K    +E +++RK E   + +       E+E
Sbjct: 213 ERERETETETERKRQTDRERDRQRKTEREREKQAERERASERE 255


>gi|30581135 structural maintenance of chromosomes 1A [Homo sapiens]
          Length = 1233

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 27/106 (25%), Positives = 52/106 (49%), Gaps = 1/106 (0%)

Query: 21  IQKKVREHHRKLRKEAKKRGHKKPRKDPGVPNSAPFKEALLREAELRKQRLEELKQQQKL 80
           ++K  +E   ++ +E++ +G     ++  V      KE   + A    Q LE+  + QK 
Sbjct: 343 VEKARQEFEERMEEESQSQGRDLTLEENQVKKYHRLKEEASKRAATLAQELEKFNRDQKA 402

Query: 81  DRQK-ELEKKRKLETNPDIKPSNVEPMEKEFGLCKTENKAKSGKQN 125
           D+ + +LE+++K+ET   IK    E  E +  + K E    + KQ+
Sbjct: 403 DQDRLDLEERKKVETEAKIKQKLREIEENQKRIEKLEEYITTSKQS 448



 Score = 29.3 bits (64), Expect = 9.8
 Identities = 34/150 (22%), Positives = 68/150 (45%), Gaps = 34/150 (22%)

Query: 22  QKKVREHHRKLRKEAKKRG------------HKKPRKD-------PGVPNSAPFKEALLR 62
           + +V+++HR L++EA KR              +K  +D         V   A  K+ L R
Sbjct: 369 ENQVKKYHR-LKEEASKRAATLAQELEKFNRDQKADQDRLDLEERKKVETEAKIKQKL-R 426

Query: 63  EAELRKQRLEELKQ-----QQKLDRQKELEKKRKLETNPDIKPSNVEPMEKEFGLCKTE- 116
           E E  ++R+E+L++     +Q L+ QK+LE   +L    ++    ++ + KE      + 
Sbjct: 427 EIEENQKRIEKLEEYITTSKQSLEEQKKLE--GELTEEVEMAKRRIDEINKELNQVMEQL 484

Query: 117 -----NKAKSGKQNSKKLYCQELKKVIEAS 141
                ++ +S +Q  K    + +K++   S
Sbjct: 485 GDARIDRQESSRQQRKAEIMESIKRLYPGS 514


>gi|148746195 trichohyalin [Homo sapiens]
          Length = 1943

 Score = 42.0 bits (97), Expect = 0.001
 Identities = 24/72 (33%), Positives = 44/72 (61%), Gaps = 1/72 (1%)

Query: 22  QKKVREHHRKLRKEAKKRGHKKPRKDPGVPNSAPFKEALLREAELRKQRLEELKQQQKLD 81
           +K+ R+    LRKE +K   ++P++   +         L R+ ELR++R EE +QQQ+L 
Sbjct: 243 EKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQ-ELRRERQEEEQQQQRLR 301

Query: 82  RQKELEKKRKLE 93
           R+++L +K++ E
Sbjct: 302 REQQLRRKQEEE 313



 Score = 37.0 bits (84), Expect = 0.047
 Identities = 16/99 (16%), Positives = 54/99 (54%)

Query: 1   MKRPKLKKASKRMTCHKRYKIQKKVREHHRKLRKEAKKRGHKKPRKDPGVPNSAPFKEAL 60
           ++R + ++  ++    +  ++++K  E  R+ ++E +++  ++ +++         ++  
Sbjct: 286 LRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEE 345

Query: 61  LREAELRKQRLEELKQQQKLDRQKELEKKRKLETNPDIK 99
            RE +LR+++ EE ++QQ    Q+E  ++++L     ++
Sbjct: 346 RREQQLRREQEEERREQQLRREQEEERREQQLRREQQLR 384



 Score = 35.8 bits (81), Expect = 0.10
 Identities = 22/97 (22%), Positives = 52/97 (53%), Gaps = 4/97 (4%)

Query: 7    KKASKRMTCHKRYKIQKKVREHHRKLRKEA--KKRGHKKPRKDPGVPNSAPFKEALLREA 64
            ++  +R    ++Y+ +++V++   +L +E   K+R  +  R+          +E LLRE 
Sbjct: 1128 REKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREE 1187

Query: 65   E--LRKQRLEELKQQQKLDRQKELEKKRKLETNPDIK 99
            +   R++R  + +++++L RQK  ++ R  +   D+K
Sbjct: 1188 QEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLK 1224



 Score = 35.4 bits (80), Expect = 0.14
 Identities = 21/93 (22%), Positives = 52/93 (55%), Gaps = 3/93 (3%)

Query: 7    KKASKRMTCHKRYKIQKKVREHHRKLRKEA--KKRGHKKPRKDPGVPNSAPFKEALLREA 64
            ++  +R    ++Y+ ++++++   +L +E   K+R  ++ R+          +E LLRE 
Sbjct: 1068 RETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLRE- 1126

Query: 65   ELRKQRLEELKQQQKLDRQKELEKKRKLETNPD 97
            E  K+R +EL++Q + + + + E+++ L   P+
Sbjct: 1127 EREKRRRQELERQYREEEEVQQEEEQLLREEPE 1159



 Score = 34.7 bits (78), Expect = 0.23
 Identities = 34/158 (21%), Positives = 75/158 (47%), Gaps = 11/158 (6%)

Query: 2    KRPKLKKASKRMTCHKRYKIQKK----VREHHRKLRKEAKKRGHKKPRK----DPGVPNS 53
            +R K ++  +     +  ++Q++    +RE   K R++ ++R ++K +K    +  +   
Sbjct: 917  EREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGE 976

Query: 54   APFKEALLREAELRKQRLEELKQQQKLDRQKELEKKRKLETNPDIKPSNVEPMEKEFGLC 113
             P K    +E E + +  EEL+Q+++   ++E EK+R+ E     +  +    E+E  L 
Sbjct: 977  EPEKRRR-QEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLL- 1034

Query: 114  KTENKAKSGKQNSKKLYCQELKKVIEASDVVLEVLDAR 151
              E + K   Q  ++ Y +E +   E   ++ E  + R
Sbjct: 1035 -REEREKRRLQERERQYREEEELQQEEEQLLGEERETR 1071



 Score = 33.5 bits (75), Expect = 0.52
 Identities = 25/137 (18%), Positives = 68/137 (49%), Gaps = 7/137 (5%)

Query: 2   KRPKLKKASKRMTCHKRYKIQKKVREHHRKLRKEAKKRGHKKPRKDPGVPNSAPFK--EA 59
           +  +L++  +     ++ + +++     ++LR+E + R  ++ R++  +      +  + 
Sbjct: 347 REQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQ 406

Query: 60  LLREAELRKQRLEELKQQQKLDRQKELEKKRKLETNPDIKPSNVEPMEKEFGLCKTENKA 119
           L RE +LR++  ++L+++Q+L R++E E+  +       +       E+     K E + 
Sbjct: 407 LRREQQLRRE--QQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEET 464

Query: 120 KSGKQNSKKLYCQELKK 136
           +  +Q  +K   Q+LK+
Sbjct: 465 ERHEQERRK---QQLKR 478



 Score = 33.1 bits (74), Expect = 0.68
 Identities = 26/135 (19%), Positives = 68/135 (50%), Gaps = 8/135 (5%)

Query: 2   KRPKLKKASKRMTCHKRYKIQKKVREHHRK-----LRKEAKKRGHKKPRKDPGVPNSAPF 56
           +  +LK+  +     +R + ++++R    +     L++E +KR  ++ R+          
Sbjct: 515 REQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEER 574

Query: 57  KEALLREAELRKQRLEELKQQQKLDRQKELEKKRKLETNP--DIKPSNVEP-MEKEFGLC 113
           ++ LL+  E R+Q+  + +Q+++L+++ + E+  +LE     + +    EP  E+   L 
Sbjct: 575 RDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLL 634

Query: 114 KTENKAKSGKQNSKK 128
           K+E + +  +Q  ++
Sbjct: 635 KSEEQEERRQQQLRR 649



 Score = 32.7 bits (73), Expect = 0.88
 Identities = 37/179 (20%), Positives = 83/179 (46%), Gaps = 13/179 (7%)

Query: 7    KKASKRMTCHKRYKIQKKVREHHRKLRKEA--KKRGHKKPRKDPGVPNSAPFKEALL--- 61
            ++  +R    ++Y+ + ++++   +L +E   K+R  ++ R+          +E LL   
Sbjct: 1008 REKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEE 1067

Query: 62   ----REAELRKQ--RLEELKQQQKLDRQKELEKKRKLETNPDIKPSNVEPMEKEFGLCKT 115
                R  EL +Q  + EEL+Q+++   ++E EK+R+ E     +    E +++E      
Sbjct: 1068 RETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREE--EELQQEEEQLLR 1125

Query: 116  ENKAKSGKQNSKKLYCQELKKVIEASDVVLEVLDARDPLGCRCPQVEEAIVQSGQKKLV 174
            E + K  +Q  ++ Y +E +   E   ++ E  + R          EE  +Q  +++L+
Sbjct: 1126 EEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLL 1184



 Score = 31.6 bits (70), Expect = 2.0
 Identities = 21/105 (20%), Positives = 49/105 (46%), Gaps = 3/105 (2%)

Query: 5    KLKKASKRMTCHKRYKIQKKVREHHRKLRKEAKKRGHKKPRKDPGVPNSAPFKEALLREA 64
            K ++  +   C +  ++Q+   E  + LR+E +KR  ++  +          +E  L   
Sbjct: 1100 KRRRQERERQCREEEELQQ---EEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLRE 1156

Query: 65   ELRKQRLEELKQQQKLDRQKELEKKRKLETNPDIKPSNVEPMEKE 109
            E  K+R +EL++Q + + + + E+++ L    + +    E   +E
Sbjct: 1157 EPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYRE 1201



 Score = 31.2 bits (69), Expect = 2.6
 Identities = 28/128 (21%), Positives = 60/128 (46%), Gaps = 20/128 (15%)

Query: 17   KRYKIQKKVREHHRKLRKEAKKRGHKKPRKDPGVPNSAPFKEALLREAELRKQRLE-ELK 75
            +R +  +K RE  ++LR++ ++R                  + L  E +LR+Q LE + +
Sbjct: 1685 RRQERDRKFREEEQQLRRQERER------------------KFLQEEQQLRRQELERKFR 1726

Query: 76   QQQKLDRQKELEKKRKLETNPDI-KPSNVEPMEKEFGLCKTENKAKSGKQNSKKLYCQEL 134
            ++++L ++ E E+ R+ E    I +   + P  +E  L + E   K  ++   +   +E 
Sbjct: 1727 EEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQ 1786

Query: 135  KKVIEASD 142
            +   + SD
Sbjct: 1787 QLRSQESD 1794



 Score = 30.8 bits (68), Expect = 3.4
 Identities = 23/133 (17%), Positives = 65/133 (48%), Gaps = 9/133 (6%)

Query: 1   MKRPKLKKASKRMTCHKRYKIQKKVREHHRKLRKEAKKRGHKKPRKDPGVPNSAPFKEAL 60
           ++R +  +  +++   ++ + +++   H +K  +E +++  K+ +++         ++ L
Sbjct: 407 LRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEER--------RDWL 458

Query: 61  LREAELRKQRLEELKQQQKLDRQKELEKKRKLETNPDIKPSNVEPMEKEFGLCKTENKAK 120
            RE E  +   E  KQQ K D+++E  ++R L+   + +    E  E++    + E + +
Sbjct: 459 KREEETERHEQERRKQQLKRDQEEE-RRERWLKLEEEERREQQERREQQLRREQEERREQ 517

Query: 121 SGKQNSKKLYCQE 133
             K+  ++   Q+
Sbjct: 518 RLKRQEEEERLQQ 530



 Score = 30.8 bits (68), Expect = 3.4
 Identities = 29/120 (24%), Positives = 60/120 (50%), Gaps = 9/120 (7%)

Query: 20  KIQKKVREHHRKLRKEAKKRGHKKPRKDPGVPNSAPFKEALLRE--AELRKQRLEELKQQ 77
           K +++     ++LR+E ++R  ++ +++         ++ L RE   E R+Q L E +Q+
Sbjct: 635 KSEEQEERRQQQLRREQQERREQRLKREE---EEERLEQRLKREHEEERREQELAEEEQE 691

Query: 78  QKLDRQKELEKK--RKLETNPDIKPSNV--EPMEKEFGLCKTENKAKSGKQNSKKLYCQE 133
           Q  +R K    K   +LE+  D + S V   P ++E    + E + K  ++ S+  + +E
Sbjct: 692 QARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEE 751



 Score = 30.4 bits (67), Expect = 4.4
 Identities = 20/103 (19%), Positives = 57/103 (55%), Gaps = 7/103 (6%)

Query: 22  QKKVREHHRKLRKEAKKRGHKKPRKDPGVPNSAPFKEALLREAELRKQRLEELKQQQKLD 81
           Q++++E   +LRK  ++   ++ +++         ++ L RE +LR+++ EE ++QQ+ +
Sbjct: 268 QRELQEEEEQLRKLERQELRRERQEEEQQ------QQRLRREQQLRRKQEEERREQQE-E 320

Query: 82  RQKELEKKRKLETNPDIKPSNVEPMEKEFGLCKTENKAKSGKQ 124
           R+++ E++ + E   + +    +   +E  L + + + +  +Q
Sbjct: 321 RREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQ 363



 Score = 30.4 bits (67), Expect = 4.4
 Identities = 21/86 (24%), Positives = 44/86 (51%), Gaps = 10/86 (11%)

Query: 11   KRMTCHKRYKIQKKVR-EHHRKLRKEAKKRGHKKPRKDPGVPNSAPFKEALLREAELRKQ 69
            +R    ++Y+ +++++ E  + LR+E +KR  ++ R+         ++E    + + RKQ
Sbjct: 1162 RRQELERQYREEEELQQEEEQLLREEQEKRRQERERQ---------YREEEELQRQKRKQ 1212

Query: 70   RLEELKQQQKLDRQKELEKKRKLETN 95
            R  +  Q+  L  Q E EK+  +  N
Sbjct: 1213 RYRDEDQRSDLKWQWEPEKENAVRDN 1238



 Score = 30.4 bits (67), Expect = 4.4
 Identities = 27/127 (21%), Positives = 61/127 (48%), Gaps = 17/127 (13%)

Query: 2    KRPKLKKASKRMTCHKRYKIQKKVREHHRKLRKEAKKRGHKKPRKDPGVPNSAPFKEALL 61
            + P+ K   +    H++ + Q+K  +  ++LR++ + +  ++ R          F+E   
Sbjct: 1511 QEPERKFLEEEQQLHRQQR-QRKFLQEEQQLRRQERGQQRRQDR-------DRKFRE--- 1559

Query: 62   REAELRKQRLEELKQQQKLDRQKELEKKRKLETNPDIKPSNVEPMEKEFGLCKTENKAKS 121
             E +LR++R E+   +Q+ DR+  LE+++      + K      ME E  L + E + + 
Sbjct: 1560 -EEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERK-----FMEDEQQLRRQEGQQQL 1613

Query: 122  GKQNSKK 128
             ++  +K
Sbjct: 1614 RQERDRK 1620



 Score = 30.0 bits (66), Expect = 5.7
 Identities = 27/116 (23%), Positives = 56/116 (48%), Gaps = 15/116 (12%)

Query: 21   IQKKVREHHRKLRKEAKKRGHKKPRKDPGVPNSAPFKEALLREAELRKQRLEELKQQQK- 79
            +Q  + E   + R++ ++R  ++ R  P        +E L RE +   +R +   Q++K 
Sbjct: 1267 LQHLLGEQQERDREQERRRWQQRDRHFPE-------EEQLEREEQKEAKRRDRKSQEEKQ 1319

Query: 80   LDRQKELEKKRKLETNPDIKPSNVEPMEKEFGLCKTENKAKSGKQNSKKLYCQELK 135
            L R++  EK+R+ ET+   +       E+E  L + E +    ++  +K   +EL+
Sbjct: 1320 LLREEREEKRRRQETDRKFR-------EEEQLLQEREEQPLRRQERDRKFREEELR 1368



 Score = 29.6 bits (65), Expect = 7.5
 Identities = 29/142 (20%), Positives = 64/142 (45%), Gaps = 20/142 (14%)

Query: 7    KKASKRMTCHKRYKIQKKVREHHRKL--------RKEAKKRGHKKPRKDPGVPNSAPFKE 58
            ++  +R T + +  +Q+++R+  + L        R+E +KR  ++  +          +E
Sbjct: 881  ERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEE 940

Query: 59   ALLREAELRKQRLEELKQQQKLDRQ----------KELEKKRKLETNPDIKPSNVEPMEK 108
              L   E  K+R +E ++Q + D++          +E EK+R+ E   + K    E +++
Sbjct: 941  EQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQER--EKKYREEEELQQ 998

Query: 109  EFGLCKTENKAKSGKQNSKKLY 130
            E      E + K  +Q  ++ Y
Sbjct: 999  EEEQLLREEREKRRRQEWERQY 1020



 Score = 29.3 bits (64), Expect = 9.8
 Identities = 24/103 (23%), Positives = 51/103 (49%), Gaps = 13/103 (12%)

Query: 20  KIQKKVREHHRKLRKEAKKRGHKKPRKDPGVP-------NSAPFKEALLR--EAELRKQR 70
           K +++   H ++ RK+  KR  ++ R++  +             +E  LR  + E R+QR
Sbjct: 459 KREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQR 518

Query: 71  L----EELKQQQKLDRQKELEKKRKLETNPDIKPSNVEPMEKE 109
           L    EE + QQ+L  +++L ++++      +K    + +E+E
Sbjct: 519 LKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQE 561



 Score = 29.3 bits (64), Expect = 9.8
 Identities = 21/90 (23%), Positives = 50/90 (55%), Gaps = 7/90 (7%)

Query: 11  KRMTCHKRYKIQKKVREH-HRKLRKEAKKRGHKKPRKDPGVPNSAPFKEA---LLR---E 63
           KR    ++ +++++  E   ++L++E  +R  ++ R++  +    P +E    LL+   +
Sbjct: 580 KREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQ 639

Query: 64  AELRKQRLEELKQQQKLDRQKELEKKRKLE 93
            E R+Q+L   +Q+++  R K  E++ +LE
Sbjct: 640 EERRQQQLRREQQERREQRLKREEEEERLE 669



 Score = 29.3 bits (64), Expect = 9.8
 Identities = 20/80 (25%), Positives = 43/80 (53%), Gaps = 5/80 (6%)

Query: 22   QKKVREHHRKLRKEAKKRGHKKPRKDPGVPNSAPFKEALLREAELRKQRLEELKQQQKLD 81
            Q + +E +RK+ +E + R  ++ ++         F+E    E +LR++R E+  + Q+ D
Sbjct: 1739 QLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFRE----EEQLRQEREEQQLRSQESD 1794

Query: 82   RQ-KELEKKRKLETNPDIKP 100
            R+ +E E+ R+      ++P
Sbjct: 1795 RKFREEEQLRQEREEQQLRP 1814


>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
           sapiens]
          Length = 668

 Score = 41.6 bits (96), Expect = 0.002
 Identities = 32/144 (22%), Positives = 73/144 (50%), Gaps = 15/144 (10%)

Query: 5   KLKKASKRMTCH-KRYKIQKKVREHHRKLRKEAKKRGHKKPRKDPGVPNSAPFKEALLRE 63
           K+++  KR     K ++ ++K+RE   K+R++ KK   ++ +           ++  +RE
Sbjct: 404 KIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIH---------EQEKIRE 454

Query: 64  AELRKQRLEELKQQQKLDRQKEL-EKKRKLETNPDIKPSNVEPMEKEFGLCKTENKAKSG 122
            E R+++ E  +Q++K+  Q+E+  +K K+     I+    +   +E  +   E K    
Sbjct: 455 EEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKI--- 511

Query: 123 KQNSKKLYCQELKKVIEASDVVLE 146
           ++  +K++ QE +K+ E  + + E
Sbjct: 512 REQEEKMWRQE-EKIREQEEKIRE 534



 Score = 39.7 bits (91), Expect = 0.007
 Identities = 27/133 (20%), Positives = 65/133 (48%), Gaps = 14/133 (10%)

Query: 17  KRYKIQKKVREHHRKLRKEAKKRGHKKPRKDPGVPNSAPFKEALLREAELRKQRLEELKQ 76
           K ++ ++K+RE   K+R++ +K   ++             +E +  + ++R+Q  +  +Q
Sbjct: 517 KMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQ 576

Query: 77  QQKLDRQKE---------LEKKRKLETNPDIKPSNVEPM-EKEFGLCKTENKAKSG---- 122
           ++K+  QKE          E++ K+    ++     E M E+E  +C+ E K +      
Sbjct: 577 EEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKM 636

Query: 123 KQNSKKLYCQELK 135
           ++  +K++ QE++
Sbjct: 637 RRQEEKMWEQEVR 649



 Score = 33.5 bits (75), Expect = 0.52
 Identities = 24/131 (18%), Positives = 66/131 (50%), Gaps = 3/131 (2%)

Query: 7   KKASKRMTCHKRYKIQKKVREHHRKLRKEAKKRGHKKPRKDPGVPNSAPFKEALLREAEL 66
           +K  K     ++   Q+K+RE   K ++E K R  +K R++         ++   +E ++
Sbjct: 374 EKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEK-RQEQEAKMWRQEEKIREQEEKI 432

Query: 67  RKQRLEELKQQQKLDRQKELEKKRKLETNPDI--KPSNVEPMEKEFGLCKTENKAKSGKQ 124
           R+Q  +  +Q++K+  Q+++ ++ K +   ++  +   +   E+ +   +  ++ +  ++
Sbjct: 433 REQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRK 492

Query: 125 NSKKLYCQELK 135
             +K++ QE K
Sbjct: 493 QEEKVWRQEEK 503



 Score = 30.0 bits (66), Expect = 5.7
 Identities = 25/86 (29%), Positives = 43/86 (50%), Gaps = 11/86 (12%)

Query: 465 EEKDIHEELPKRKERKQEE-----REDDKDSDQETVDEEVDENSSGMFAAEE---TGEAL 516
           EEK   EE  + +E++QE+     R+++K  +QE   E++ E    M+  EE     E +
Sbjct: 396 EEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQE---EKIREQEKKMWRQEEKIHEQEKI 452

Query: 517 SEETTAGEQSTRSFILDKIIEEDDAY 542
            EE    EQ       +KI E+++ +
Sbjct: 453 REEEKRQEQEEMWRQEEKIREQEEIW 478


>gi|4503179 oral-facial-digital syndrome 1 [Homo sapiens]
          Length = 1012

 Score = 41.2 bits (95), Expect = 0.002
 Identities = 32/128 (25%), Positives = 64/128 (50%), Gaps = 5/128 (3%)

Query: 22  QKKVREHHRKLRKEAKKRGHKKPRKDPGVPNSAPFKEALLREAELRKQRLEELKQQQKLD 81
           QK++ E   + +   ++   ++ R++    N     E   RE E   Q  + +++  K+ 
Sbjct: 870 QKQIEEQKEEEKIREQQVKERRQREERRQSNLQEVLERERRELEKLYQERKMIEESLKIK 929

Query: 82  RQKELEKKRKLE-TNPDIKPSNVE---PMEKEFGLCKTENKAKSGKQNSKKLYCQ-ELKK 136
            +KELE + +LE +N +IK  +     P+EK   + + E   +S  ++SKK+  +  L  
Sbjct: 930 IKKELEMENELEMSNQEIKDKSAHSENPLEKYMKIIQQEQDQESADKSSKKMVQEGSLVD 989

Query: 137 VIEASDVV 144
            +++SD V
Sbjct: 990 TLQSSDKV 997


>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
           sapiens]
          Length = 750

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 30/134 (22%), Positives = 69/134 (51%), Gaps = 15/134 (11%)

Query: 5   KLKKASKRMTCH-KRYKIQKKVREHHRKLRKEAKKRGHKKPRKDPGVPNSAPFKEALLRE 63
           K+++  KR     K ++ ++K+RE   K+R++ KK   ++ +           ++  +RE
Sbjct: 418 KIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIH---------EQEKIRE 468

Query: 64  AELRKQRLEELKQQQKLDRQKEL--EKKRKLETNPDIKPSNVEPMEKEFGLCKTENKAKS 121
            E R+++ E  +Q++K+  Q+E+  +K++  E    I+    +   +E  + + E K   
Sbjct: 469 EEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKI-- 526

Query: 122 GKQNSKKLYCQELK 135
            ++  +K++ QE K
Sbjct: 527 -REQEEKMWRQEEK 539



 Score = 34.3 bits (77), Expect = 0.30
 Identities = 23/119 (19%), Positives = 59/119 (49%), Gaps = 9/119 (7%)

Query: 22  QKKVREHHRKLRKEAKKRGHKKPRKDPGVPNSAPFKEALLREAELRKQRLEELKQQQKLD 81
           ++K+RE   K+R++ +    ++ +           +E +  + E   ++ E++++Q+K  
Sbjct: 625 EEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKKI 684

Query: 82  RQKELEKKRKLETNPDIKPSNVEPM-EKEFGLCKTENKAKSG----KQNSKKLYCQELK 135
           R++E     K+    ++     E M E+E  +C+ E K +      ++  +K++ QE++
Sbjct: 685 REQE----EKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVR 739



 Score = 33.5 bits (75), Expect = 0.52
 Identities = 33/141 (23%), Positives = 61/141 (43%), Gaps = 15/141 (10%)

Query: 17  KRYKIQKKVREHHRKLRKEAKKRGHKK---PRKDPGVPNSAPFKEALLREAELRKQRLEE 73
           K ++ ++K+RE     R+E K    +K     K     +    +E  +RE E +  R EE
Sbjct: 532 KMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEE 591

Query: 74  LKQQQKLDRQKELEKKRKLETNPDIKPSNVEPME----------KEFGLCKTENKAKSGK 123
             ++Q+  RQ++ EK  K E     +   ++  E          +E      E + K G+
Sbjct: 592 KIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGE 651

Query: 124 QNSKKLYCQELKKVIEASDVV 144
           Q  K   C++ +K+ E  + +
Sbjct: 652 QEEK--MCEQEEKMQEQEETM 670



 Score = 32.3 bits (72), Expect = 1.2
 Identities = 19/92 (20%), Positives = 48/92 (52%), Gaps = 1/92 (1%)

Query: 7   KKASKRMTCHKRYKIQKKVREHHRKLRKEAKKRGHKKPRKDPGVPNSAPFKEALLREAEL 66
           +K  K     ++   Q+K+RE   K ++E K R  +K R++         ++   +E ++
Sbjct: 388 EKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEK-RQEQEAKMWRQEEKIREQEEKI 446

Query: 67  RKQRLEELKQQQKLDRQKELEKKRKLETNPDI 98
           R+Q  +  +Q++K+  Q+++ ++ K +   ++
Sbjct: 447 REQEKKMWRQEEKIHEQEKIREEEKRQEQEEM 478



 Score = 32.3 bits (72), Expect = 1.2
 Identities = 27/136 (19%), Positives = 67/136 (49%), Gaps = 7/136 (5%)

Query: 2   KRPKLKKASKRMTCHKRYKIQKKVREHHRKLRKEAKKRGHKKPRKDPGVPNSAPFKEALL 61
           ++ K+++  KR    + ++ ++K+ E     R+  K++ H++  K          +E  +
Sbjct: 462 EQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQ--KEKMHEQEEKIRKQEEKVWRQEEKI 519

Query: 62  REAE--LRKQRLEELKQQQKLDRQKELEKKRKLETNPDIKPSNVEPMEKEFGLCKTENKA 119
           RE E  +R+Q  +  +Q++K+  Q+E+ ++ +     +      +  E+E  + + E K 
Sbjct: 520 REQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKI 579

Query: 120 KSGKQNSKKLYCQELK 135
              ++  +K++ QE K
Sbjct: 580 ---REQEEKVWRQEEK 592



 Score = 30.0 bits (66), Expect = 5.7
 Identities = 25/86 (29%), Positives = 43/86 (50%), Gaps = 11/86 (12%)

Query: 465 EEKDIHEELPKRKERKQEE-----REDDKDSDQETVDEEVDENSSGMFAAEE---TGEAL 516
           EEK   EE  + +E++QE+     R+++K  +QE   E++ E    M+  EE     E +
Sbjct: 410 EEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQE---EKIREQEKKMWRQEEKIHEQEKI 466

Query: 517 SEETTAGEQSTRSFILDKIIEEDDAY 542
            EE    EQ       +KI E+++ +
Sbjct: 467 REEEKRQEQEEMWRQEEKIHEQEEIW 492


>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
          Length = 793

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 53/238 (22%), Positives = 98/238 (41%), Gaps = 33/238 (13%)

Query: 7   KKASKRMTCHKRYKIQKKVREHHRKLRKEAKKRGHKKPRKDPGVPNS---------APFK 57
           ++ S  ++ H++ + + K R    + R EA++R   K  +D  + +          A  +
Sbjct: 245 EQGSDEISHHEKMEEEDKERAEAERARLEAEERERIKAEQDKKIADERARIEAEEKAAAQ 304

Query: 58  EALLREAELRKQRLEELKQQQKLDRQKELEKKRKLETNPDIKPSNVEPMEKEFGLCKTEN 117
           E   REAE R++  EE K+  +  ++ + E+KR  E    IK       E+   + + E 
Sbjct: 305 ERERREAEERERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEK 364

Query: 118 KAKSGKQNSKKLYCQELKKVIEASDVVLEVLDARDPLGCRCPQVEEAIVQSGQKKLVLIL 177
           +A   +Q ++    +E  KV E                 R  Q+EE      + K+    
Sbjct: 365 RAAEERQRARAEE-EEKAKVEEQK---------------RNKQLEEKKHAMQETKI---- 404

Query: 178 NKSDLVPKENLESWLNYLKKE---LPTVVFRASTKPKDKGKITKRVKAKKNAAPFRSE 232
            K + V ++    W+N  K +   L T V +   + K      KR K +++   F+ E
Sbjct: 405 -KGEKVEQKIEGKWVNEKKAQEDKLQTAVLKKQGEEKGTKVQAKREKLQEDKPTFKKE 461



 Score = 35.8 bits (81), Expect = 0.10
 Identities = 48/198 (24%), Positives = 90/198 (45%), Gaps = 27/198 (13%)

Query: 2   KRPKLKKASKRMTCHKRYKI---QKKVREHHRKLRKEAKKRGHKKPRKDPGVPNSAPFKE 58
           +R ++++  KR    +R +I   +K+  E  +++++E K+   ++ R       +A  ++
Sbjct: 313 ERERMREEEKR-AAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQ 371

Query: 59  ALLREAELRKQRLEELKQQQKLDRQKELEKKRKLETNPDIKPSNVEPMEKEFGLCKTENK 118
               E E  K ++EE K      R K+LE+K+       IK   VE  +K  G    E K
Sbjct: 372 RARAEEE-EKAKVEEQK------RNKQLEEKKHAMQETKIKGEKVE--QKIEGKWVNEKK 422

Query: 119 AKSGKQNSKKLYCQELKKVIEASDVVLEVLDARDPLGCRCPQVEEAIVQSGQKKLVLILN 178
           A+       KL    LKK  +  +   +V   R+ L    P  ++  ++   +K+     
Sbjct: 423 AQ-----EDKLQTAVLKK--QGEEKGTKVQAKREKLQEDKPTFKKEEIK--DEKI----- 468

Query: 179 KSDLVPKENLESWLNYLK 196
           K D  PKE ++S+++  K
Sbjct: 469 KKDKEPKEEVKSFMDRKK 486



 Score = 32.0 bits (71), Expect = 1.5
 Identities = 41/197 (20%), Positives = 77/197 (39%), Gaps = 33/197 (16%)

Query: 22  QKKVREHHRKLRKEAKKRGHKKPRKDPGVPNSAP--------------------FKEALL 61
           +++ R+   + ++E +  G    + +    NS P                    F E L 
Sbjct: 42  RRRARQERLRQKQEEESLGQVTDQVEVNAQNSVPDEEAKTTTTNTQVEGDDEAAFLERLA 101

Query: 62  REAELRKQRLEELKQQQK------LDRQKELEKKR----KLETNPDIKPSNVEPMEKEFG 111
           R  E R++RL+E  ++QK       D    L  +R      E     K    E  ++ + 
Sbjct: 102 RREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQERYE 161

Query: 112 LCKTENKAKSGKQNSKKLYCQELKKVIEASDVVLEVLDARDPLGCRCPQ--VEEAIVQSG 169
           + +TE   KS ++N  +   +E KK  +  +   E    R  +G    +  VEE   +S 
Sbjct: 162 IEETETVTKSYQKNDWR-DAEENKKEDKEKEEEEEEKPKRGSIGENQVEVMVEEKTTESQ 220

Query: 170 QKKLVLILNKSDLVPKE 186
           ++ +V+ L    +  +E
Sbjct: 221 EETVVMSLKNGQISSEE 237



 Score = 29.6 bits (65), Expect = 7.5
 Identities = 17/64 (26%), Positives = 29/64 (45%)

Query: 466 EKDIHEELPKRKERKQEEREDDKDSDQETVDEEVDENSSGMFAAEETGEALSEETTAGEQ 525
           E +  E + + ++R  EER+  K+ ++   +E          AAEE      EE  A E+
Sbjct: 310 EAEERERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEE 369

Query: 526 STRS 529
             R+
Sbjct: 370 RQRA 373



 Score = 29.3 bits (64), Expect = 9.8
 Identities = 20/64 (31%), Positives = 29/64 (45%), Gaps = 3/64 (4%)

Query: 465 EEKDIHEELPKRKERKQEEREDDKDSDQETVDEEVDENSSGMFAAEETGEALSEETTAGE 524
           EEK   +E   R+ R+ EERE  ++ ++   +E          AAEE      EE  A E
Sbjct: 298 EEKAAAQE---RERREAEERERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAE 354

Query: 525 QSTR 528
           +  R
Sbjct: 355 ERQR 358


>gi|84043963 eukaryotic translation initiation factor 5B [Homo
           sapiens]
          Length = 1220

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 25/87 (28%), Positives = 45/87 (51%), Gaps = 9/87 (10%)

Query: 464 IEEKDIHEEL---PKRKERKQEEREDDKDSDQETVDEEVDENSSGMFAAEETGEALSEET 520
           +E   +H E+   P+ +E ++EE E+D++S++E  +E   E S G    +E  E +S+E 
Sbjct: 518 VEGNKVHIEVKENPEEEEEEEEEEEEDEESEEEEEEEGESEGSEG----DEEDEKVSDEK 573

Query: 521 TAGEQSTRSFILDKIIEEDDAYDFSTD 547
            +G+   +     K +  D  YD   D
Sbjct: 574 DSGKTLDKK--PSKEMSSDSEYDSDDD 598



 Score = 39.3 bits (90), Expect = 0.009
 Identities = 36/131 (27%), Positives = 60/131 (45%), Gaps = 12/131 (9%)

Query: 26  REHHRKLRKEAKKRGHKKPRKDPGVPNSAPFKEAL--LREAELRKQRLEELKQQQKLDRQ 83
           ++  +K +K  K+   K+ +K P        +EAL  L+E E R++R EE    +++ R 
Sbjct: 314 KKKDKKKKKGEKEEKEKEKKKGPSKATVKAMQEALAKLKEEEERQKREEE----ERIKRL 369

Query: 84  KELEKKRK----LETNPDIKPSNVEPMEKEFGLCKTENKAKSGKQNSKKLYCQELKKVIE 139
           +ELE KRK    LE     +    E   KE    K E K  +  Q   +   +   K+++
Sbjct: 370 EELEAKRKEEERLEQEKRERKKQKEKERKE--RLKKEGKLLTKSQREARARAEATLKLLQ 427

Query: 140 ASDVVLEVLDA 150
           A  V +   D+
Sbjct: 428 AQGVEVPSKDS 438



 Score = 30.4 bits (67), Expect = 4.4
 Identities = 19/79 (24%), Positives = 37/79 (46%), Gaps = 7/79 (8%)

Query: 465 EEKDIHEELPKRKERKQEEREDDKDSDQETVDEEVDENSSGMFAAEETGEALSEETTAGE 524
           EE++  EE  + +E ++EE E +     E  ++  DE  SG    ++  + +S ++    
Sbjct: 536 EEEEEEEEDEESEEEEEEEGESEGSEGDEEDEKVSDEKDSGKTLDKKPSKEMSSDSEYDS 595

Query: 525 QSTRSFILDKIIEEDDAYD 543
              R+       +E+ AYD
Sbjct: 596 DDDRT-------KEERAYD 607


>gi|116089325 splicing factor, arginine/serine-rich 12 isoform a
           [Homo sapiens]
          Length = 624

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 28/135 (20%), Positives = 59/135 (43%), Gaps = 9/135 (6%)

Query: 3   RPKLKKASKRMTCHKRYKIQKKVREHHRKLRKEAKKRGHKKPRKDPGVPNSAPFKEALLR 62
           R K + +SK  +  KR + + + R H+R   ++  +R  K P K            +   
Sbjct: 313 RSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSH 372

Query: 63  EAELRKQRLEELKQQQKL---------DRQKELEKKRKLETNPDIKPSNVEPMEKEFGLC 113
             + RK   E++K+++++         +R+KE EK+++   N D      +  EK+    
Sbjct: 373 SRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKD 432

Query: 114 KTENKAKSGKQNSKK 128
           +   + K  +++  K
Sbjct: 433 REREREKEHEKDRDK 447



 Score = 37.0 bits (84), Expect = 0.047
 Identities = 24/91 (26%), Positives = 44/91 (48%), Gaps = 2/91 (2%)

Query: 3   RPKLKKASKRMTCHKRYKIQKKVREHHRKLRKEAKKRGHKKPRKDPGVPNSAPFKEALLR 62
           R +     KR    ++ K +++V+E  R+  +E +K   K+  K+ G       +    R
Sbjct: 368 RSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKE--KERGKNKDRDKEREKDR 425

Query: 63  EAELRKQRLEELKQQQKLDRQKELEKKRKLE 93
           E +  K R  E +++ + DR KE EK++  E
Sbjct: 426 EKDKEKDREREREKEHEKDRDKEKEKEQDKE 456



 Score = 36.2 bits (82), Expect = 0.080
 Identities = 31/138 (22%), Positives = 62/138 (44%), Gaps = 15/138 (10%)

Query: 2   KRPKLKKASKRMTCHKRYKIQKKVREHHRKLRKEAKKRGHKKPRKDPGVPNSAPFKEALL 61
           K  +  K+  +     R + + + R H R  RK+ +++  +K R           ++   
Sbjct: 346 KDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVK---------EKDRE 396

Query: 62  REAELRKQRLEELKQQQKLDRQKELEKKRKLETNPDIKPSNVEPMEKEFGLCKTENKAKS 121
           +E E  K+R +E ++ +  DR KE EK R+ +   D +    +  EK+       +K K 
Sbjct: 397 KEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKD------RDKEKE 450

Query: 122 GKQNSKKLYCQELKKVIE 139
            +Q+ +K   ++  K I+
Sbjct: 451 KEQDKEKEREKDRSKEID 468



 Score = 36.2 bits (82), Expect = 0.080
 Identities = 26/142 (18%), Positives = 62/142 (43%), Gaps = 12/142 (8%)

Query: 7   KKASKRMTCHKRYKIQKKVREHHRKLRKEAKK---RGHKKPR---------KDPGVPNSA 54
           K+   R    ++ ++++K RE  R+  KE +K   RG  K R         KD       
Sbjct: 376 KRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDRER 435

Query: 55  PFKEALLREAELRKQRLEELKQQQKLDRQKELEKKRKLETNPDIKPSNVEPMEKEFGLCK 114
             ++   ++ +  K++ ++ +++++ DR KE+++KRK +      P +     +     +
Sbjct: 436 EREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSR 495

Query: 115 TENKAKSGKQNSKKLYCQELKK 136
              + +S   +      + +K+
Sbjct: 496 ERRRRRSRSSSRSPRTSKTIKR 517



 Score = 35.8 bits (81), Expect = 0.10
 Identities = 27/126 (21%), Positives = 56/126 (44%), Gaps = 16/126 (12%)

Query: 3   RPKLKKASKRMTCHKRYKIQKKVREHHRKLRKEAKKRGHKKPRKDPGVPNSAPFKEALLR 62
           R + K  S+  +  KR   ++K++E  R   K+ +K   ++                  R
Sbjct: 362 RERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKE----------------R 405

Query: 63  EAELRKQRLEELKQQQKLDRQKELEKKRKLETNPDIKPSNVEPMEKEFGLCKTENKAKSG 122
           E E  + + ++  ++++ DR+K+ EK R+ E   + +    +  EKE    K   K +S 
Sbjct: 406 EKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSK 465

Query: 123 KQNSKK 128
           + + K+
Sbjct: 466 EIDEKR 471



 Score = 35.0 bits (79), Expect = 0.18
 Identities = 31/122 (25%), Positives = 55/122 (45%), Gaps = 6/122 (4%)

Query: 12  RMTCHKRYKIQKKVREHHRKLRKEAK--KRGHKKPR---KDPGVPNSAPFKEALLREAEL 66
           R   H R K +   + H R+ R ++K   R H + R   KD     S   K +  RE   
Sbjct: 307 RSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRK 366

Query: 67  RKQRLEELKQQQKLDRQKELEKKRKLETNPDIKPSNVEPMEKEFGLCKTENKAKSGKQNS 126
            + R    + ++K  R+K  EK+R  E + + +    +  EKE    K +++ K  +++ 
Sbjct: 367 SRSR-SHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDR 425

Query: 127 KK 128
           +K
Sbjct: 426 EK 427



 Score = 29.6 bits (65), Expect = 7.5
 Identities = 21/64 (32%), Positives = 33/64 (51%), Gaps = 2/64 (3%)

Query: 464 IEEKDIHEELPKRKER-KQEEREDDKDSDQE-TVDEEVDENSSGMFAAEETGEALSEETT 521
           ++EKD  +E  + KER K++ER  +KD D+E   D E D+        E+  E   ++  
Sbjct: 390 VKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEK 449

Query: 522 AGEQ 525
             EQ
Sbjct: 450 EKEQ 453


>gi|21040255 splicing factor, arginine/serine-rich 12 isoform b
           [Homo sapiens]
          Length = 508

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 28/135 (20%), Positives = 59/135 (43%), Gaps = 9/135 (6%)

Query: 3   RPKLKKASKRMTCHKRYKIQKKVREHHRKLRKEAKKRGHKKPRKDPGVPNSAPFKEALLR 62
           R K + +SK  +  KR + + + R H+R   ++  +R  K P K            +   
Sbjct: 197 RSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSH 256

Query: 63  EAELRKQRLEELKQQQKL---------DRQKELEKKRKLETNPDIKPSNVEPMEKEFGLC 113
             + RK   E++K+++++         +R+KE EK+++   N D      +  EK+    
Sbjct: 257 SRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKD 316

Query: 114 KTENKAKSGKQNSKK 128
           +   + K  +++  K
Sbjct: 317 REREREKEHEKDRDK 331



 Score = 37.0 bits (84), Expect = 0.047
 Identities = 24/91 (26%), Positives = 44/91 (48%), Gaps = 2/91 (2%)

Query: 3   RPKLKKASKRMTCHKRYKIQKKVREHHRKLRKEAKKRGHKKPRKDPGVPNSAPFKEALLR 62
           R +     KR    ++ K +++V+E  R+  +E +K   K+  K+ G       +    R
Sbjct: 252 RSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKE--KERGKNKDRDKEREKDR 309

Query: 63  EAELRKQRLEELKQQQKLDRQKELEKKRKLE 93
           E +  K R  E +++ + DR KE EK++  E
Sbjct: 310 EKDKEKDREREREKEHEKDRDKEKEKEQDKE 340



 Score = 36.2 bits (82), Expect = 0.080
 Identities = 31/138 (22%), Positives = 62/138 (44%), Gaps = 15/138 (10%)

Query: 2   KRPKLKKASKRMTCHKRYKIQKKVREHHRKLRKEAKKRGHKKPRKDPGVPNSAPFKEALL 61
           K  +  K+  +     R + + + R H R  RK+ +++  +K R           ++   
Sbjct: 230 KDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVK---------EKDRE 280

Query: 62  REAELRKQRLEELKQQQKLDRQKELEKKRKLETNPDIKPSNVEPMEKEFGLCKTENKAKS 121
           +E E  K+R +E ++ +  DR KE EK R+ +   D +    +  EK+       +K K 
Sbjct: 281 KEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKD------RDKEKE 334

Query: 122 GKQNSKKLYCQELKKVIE 139
            +Q+ +K   ++  K I+
Sbjct: 335 KEQDKEKEREKDRSKEID 352



 Score = 36.2 bits (82), Expect = 0.080
 Identities = 26/142 (18%), Positives = 62/142 (43%), Gaps = 12/142 (8%)

Query: 7   KKASKRMTCHKRYKIQKKVREHHRKLRKEAKK---RGHKKPR---------KDPGVPNSA 54
           K+   R    ++ ++++K RE  R+  KE +K   RG  K R         KD       
Sbjct: 260 KRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDRER 319

Query: 55  PFKEALLREAELRKQRLEELKQQQKLDRQKELEKKRKLETNPDIKPSNVEPMEKEFGLCK 114
             ++   ++ +  K++ ++ +++++ DR KE+++KRK +      P +     +     +
Sbjct: 320 EREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSR 379

Query: 115 TENKAKSGKQNSKKLYCQELKK 136
              + +S   +      + +K+
Sbjct: 380 ERRRRRSRSSSRSPRTSKTIKR 401



 Score = 35.8 bits (81), Expect = 0.10
 Identities = 27/126 (21%), Positives = 56/126 (44%), Gaps = 16/126 (12%)

Query: 3   RPKLKKASKRMTCHKRYKIQKKVREHHRKLRKEAKKRGHKKPRKDPGVPNSAPFKEALLR 62
           R + K  S+  +  KR   ++K++E  R   K+ +K   ++                  R
Sbjct: 246 RERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKE----------------R 289

Query: 63  EAELRKQRLEELKQQQKLDRQKELEKKRKLETNPDIKPSNVEPMEKEFGLCKTENKAKSG 122
           E E  + + ++  ++++ DR+K+ EK R+ E   + +    +  EKE    K   K +S 
Sbjct: 290 EKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSK 349

Query: 123 KQNSKK 128
           + + K+
Sbjct: 350 EIDEKR 355



 Score = 35.0 bits (79), Expect = 0.18
 Identities = 31/122 (25%), Positives = 55/122 (45%), Gaps = 6/122 (4%)

Query: 12  RMTCHKRYKIQKKVREHHRKLRKEAK--KRGHKKPR---KDPGVPNSAPFKEALLREAEL 66
           R   H R K +   + H R+ R ++K   R H + R   KD     S   K +  RE   
Sbjct: 191 RSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRK 250

Query: 67  RKQRLEELKQQQKLDRQKELEKKRKLETNPDIKPSNVEPMEKEFGLCKTENKAKSGKQNS 126
            + R    + ++K  R+K  EK+R  E + + +    +  EKE    K +++ K  +++ 
Sbjct: 251 SRSR-SHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDR 309

Query: 127 KK 128
           +K
Sbjct: 310 EK 311



 Score = 29.6 bits (65), Expect = 7.5
 Identities = 21/64 (32%), Positives = 33/64 (51%), Gaps = 2/64 (3%)

Query: 464 IEEKDIHEELPKRKER-KQEEREDDKDSDQE-TVDEEVDENSSGMFAAEETGEALSEETT 521
           ++EKD  +E  + KER K++ER  +KD D+E   D E D+        E+  E   ++  
Sbjct: 274 VKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEK 333

Query: 522 AGEQ 525
             EQ
Sbjct: 334 EKEQ 337


>gi|24308223 hypothetical protein LOC57577 [Homo sapiens]
          Length = 936

 Score = 40.8 bits (94), Expect = 0.003
 Identities = 45/197 (22%), Positives = 86/197 (43%), Gaps = 28/197 (14%)

Query: 7   KKASKRMTCHKRYKIQKK---VREHHRKLRKEAKKRGHKKPRKDPGVPNSAPFKEALLRE 63
           +K  + MT H   K  ++    R   R++  E KK    K  ++      A  +E   RE
Sbjct: 646 RKPKQLMTPHPILKAMEERAIQRAECRRILAEKKK----KQEEEKLAQLKAQEEERQKRE 701

Query: 64  AELRKQRLEELKQQQKLDRQKELEKKRKLETNPDIKPSNVEPMEKEFGLCKTENKAKSGK 123
           AE ++ +LE  +++++L + KELEK+++++ N  ++    E  E+           K G 
Sbjct: 702 AEEKEAQLERKREEKRLKKMKELEKQKRIKRNQQLEAIAKEHYERVL-------LRKKGL 754

Query: 124 QNSKKLYCQELKKVIEASDVVLEVLDARDPLGCRCPQVEEAIVQSGQKKLVLILNKSD-- 181
           +  K+L  Q  + +  A +     L  +  L            Q  Q+ L   + ++D  
Sbjct: 755 EPWKRLRMQSKQNIQVAEEHYSLFLQRKYML---------TWFQRSQESLARKMAQADQF 805

Query: 182 ---LVPKENLESWLNYL 195
              ++ K  ++SWL Y+
Sbjct: 806 YSQILLKRVIQSWLQYV 822



 Score = 29.3 bits (64), Expect = 9.8
 Identities = 24/62 (38%), Positives = 33/62 (53%), Gaps = 7/62 (11%)

Query: 37  KKRGHKKPRKDPGVPNSAPFKEA----LLREAELRKQRLEE-LKQQQKLDRQ--KELEKK 89
           K+   KK +KDP +      K+     L RE EL  QR+E+ LK+   L+ Q   + EKK
Sbjct: 177 KENQDKKQQKDPRLTMEMRHKQVKENRLRREKELEYQRIEKTLKKSAFLEAQCLVQEEKK 236

Query: 90  RK 91
           RK
Sbjct: 237 RK 238


>gi|119709834 castor homolog 1, zinc finger isoform a [Homo sapiens]
          Length = 1759

 Score = 40.0 bits (92), Expect = 0.006
 Identities = 24/85 (28%), Positives = 43/85 (50%), Gaps = 2/85 (2%)

Query: 442  AIKGPHLANSILFQSSGLTNGIIEEKDIHEELPKRKERKQEEREDDKDSDQETVDEEVDE 501
            A  GP    +    ++G ++   EE+++  ELP+ +    E+ +DD+D D E  DE+ D+
Sbjct: 1655 AAPGPREGAAAAAAAAGESSQEDEEEEL--ELPEEEAEDDEDEDDDEDDDDEDDDEDDDD 1712

Query: 502  NSSGMFAAEETGEALSEETTAGEQS 526
                  + E   EA +E   AG ++
Sbjct: 1713 EDLRTDSEESLPEAAAEAAGAGART 1737


>gi|4759100 splicing factor, arginine/serine-rich 11 [Homo sapiens]
          Length = 484

 Score = 39.7 bits (91), Expect = 0.007
 Identities = 33/132 (25%), Positives = 63/132 (47%), Gaps = 13/132 (9%)

Query: 2   KRPKLKKASKRMTCHKRYKIQKKVREHHRKLRKEAKKRGHKKPRKDPGVP------NSAP 55
           K  K KK SK  T  K Y   ++ R   R+ R+   + G + P+K P  P      + +P
Sbjct: 315 KEDKEKKRSK--TPPKSYSTARRSRSASRERRRRRSRSGTRSPKK-PRSPKRKLSRSPSP 371

Query: 56  FKEALLREAELRKQRLEELKQ----QQKLDRQKELEKKRKLETNPDIKPSNVEPMEKEFG 111
            +    ++ +  K+R  + ++    ++K  + KE +++RK E++ D+K    +  E+E G
Sbjct: 372 RRHKKEKKKDKDKERSRDERERSTSKKKKSKDKEKDRERKSESDKDVKQVTRDYDEEEQG 431

Query: 112 LCKTENKAKSGK 123
               + K +  K
Sbjct: 432 YDSEKEKKEEKK 443



 Score = 32.3 bits (72), Expect = 1.2
 Identities = 26/125 (20%), Positives = 54/125 (43%), Gaps = 11/125 (8%)

Query: 7   KKASKRMTCHKRYKIQKK---VREHHRKLRKEAKKRGHKKPRKDPGVPNSAPFKEALLRE 63
           KK  KR     R + +++       HR+ R  +++R H K R      +    K    R 
Sbjct: 241 KKEEKRRHSRSRSRSRRRRTPSSSRHRRSRSRSRRRSHSKSR------SRRRSKSPRRRR 294

Query: 64  AELRKQRLEELKQQQKLDRQKELEKKRKLETNPDIKPSNVEPMEKEFGLCKTENKAKSGK 123
           +  R++        +  D++KE ++K++ +T P  K  +     +     +   +++SG 
Sbjct: 295 SHSRERGRRSRSTSKTRDKKKEDKEKKRSKTPP--KSYSTARRSRSASRERRRRRSRSGT 352

Query: 124 QNSKK 128
           ++ KK
Sbjct: 353 RSPKK 357


>gi|148806928 hypothetical protein LOC57482 [Homo sapiens]
          Length = 1233

 Score = 39.7 bits (91), Expect = 0.007
 Identities = 32/132 (24%), Positives = 62/132 (46%), Gaps = 11/132 (8%)

Query: 2   KRPKLKKASKRMTCHKRYK-IQKKVREHHRKLR--------KEAKKRGHKKPRKDPGVPN 52
           KR K + A KR    +R + +++++ E +R+          +E      + PR++     
Sbjct: 236 KRQKAEAAEKRRLEEQRLQALERRLWEENRRQELLEEEGEGQEPPLEAERAPREEQQRSL 295

Query: 53  SAPFKEALLREAELRKQRLEELKQQQKLDRQKELEKKRKLETNPDIKPSNVEPMEKEFGL 112
            AP  E   R     ++RLE  +++++L  Q + E++R+LE   D +       E+E G 
Sbjct: 296 EAPGWEDAERREREERERLEAEEERRRLQAQAQAEERRRLE--EDARLEERRRQEEEEGR 353

Query: 113 CKTENKAKSGKQ 124
           C  E K +  ++
Sbjct: 354 CAEELKRQEEEE 365


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.312    0.130    0.365 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 21,413,824
Number of Sequences: 37866
Number of extensions: 1027662
Number of successful extensions: 11832
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 200
Number of HSP's successfully gapped in prelim test: 411
Number of HSP's that attempted gapping in prelim test: 7706
Number of HSP's gapped (non-prelim): 3353
length of query: 549
length of database: 18,247,518
effective HSP length: 107
effective length of query: 442
effective length of database: 14,195,856
effective search space: 6274568352
effective search space used: 6274568352
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


Home | Table of Contents | Search text | Search genes | Search sequences | Purchase | FAQ | Blog | Help

Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

CSHL Press