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Search of human proteins with 45592949
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|45592949 transmembrane and immunoglobulin domain containing
[Homo sapiens]
(262 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|45592949 transmembrane and immunoglobulin domain containing [... 519 e-147
gi|115529482 neural cell adhesion molecule 1 isoform 2 [Homo sap... 66 3e-11
gi|94420689 neural cell adhesion molecule 1 isoform 1 [Homo sapi... 62 5e-10
gi|115529478 neural cell adhesion molecule 1 isoform 3 [Homo sap... 62 5e-10
gi|20127422 Down syndrome cell adhesion molecule isoform CHD2-42... 60 1e-09
gi|190358524 follistatin-like 5 isoform c [Homo sapiens] 58 1e-08
gi|190358522 follistatin-like 5 isoform b [Homo sapiens] 58 1e-08
gi|190358520 follistatin-like 5 isoform a [Homo sapiens] 58 1e-08
gi|5031927 skeletal muscle receptor tyrosine kinase [Homo sapiens] 57 1e-08
gi|126517478 peroxidasin homolog-like [Homo sapiens] 56 4e-08
gi|110431348 deleted in colorectal carcinoma [Homo sapiens] 55 5e-08
gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens] 55 5e-08
gi|54792136 follistatin-like 4 [Homo sapiens] 55 5e-08
gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens] 55 6e-08
gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens] 55 6e-08
gi|94538343 sialic acid binding Ig-like lectin 8 [Homo sapiens] 55 6e-08
gi|118572606 hemicentin 1 [Homo sapiens] 54 2e-07
gi|11321597 kinase insert domain receptor precursor [Homo sapiens] 53 2e-07
gi|75709184 contactin 3 [Homo sapiens] 53 2e-07
gi|40254891 hypothetical protein FLJ20674 [Homo sapiens] 53 3e-07
gi|33519481 neural cell adhesion molecule 2 precursor [Homo sapi... 53 3e-07
gi|193083163 roundabout, axon guidance receptor, homolog 2 isofo... 52 4e-07
gi|61888896 roundabout, axon guidance receptor, homolog 2 isofor... 52 4e-07
gi|110349719 titin isoform N2-A [Homo sapiens] 52 5e-07
gi|16506826 sialic acid binding immunoglobulin-like lectin-like ... 52 7e-07
gi|16506828 sialic acid binding immunoglobulin-like lectin-like ... 52 7e-07
gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens] 50 2e-06
gi|15826840 PTK7 protein tyrosine kinase 7 isoform a precursor [... 50 2e-06
gi|22902130 PTK7 protein tyrosine kinase 7 isoform d precursor [... 50 2e-06
gi|22902126 PTK7 protein tyrosine kinase 7 isoform b precursor [... 50 2e-06
>gi|45592949 transmembrane and immunoglobulin domain containing
[Homo sapiens]
Length = 262
Score = 519 bits (1336), Expect = e-147
Identities = 262/262 (100%), Positives = 262/262 (100%)
Query: 1 MAWKSSVIMQMGRFLLLVILFLPREMTSSVLTVNGKTENYILDTTPGSQASLICAVQNHT 60
MAWKSSVIMQMGRFLLLVILFLPREMTSSVLTVNGKTENYILDTTPGSQASLICAVQNHT
Sbjct: 1 MAWKSSVIMQMGRFLLLVILFLPREMTSSVLTVNGKTENYILDTTPGSQASLICAVQNHT 60
Query: 61 REEELLWYREEGRVDLKSGNKINSSSVCVSSISENDNGISFTCRLGRDQSVSVSVVLNVT 120
REEELLWYREEGRVDLKSGNKINSSSVCVSSISENDNGISFTCRLGRDQSVSVSVVLNVT
Sbjct: 61 REEELLWYREEGRVDLKSGNKINSSSVCVSSISENDNGISFTCRLGRDQSVSVSVVLNVT 120
Query: 121 FPPLLSGNDFQTVEEGSNVKLVCNVKANPQAQMMWYKNSSLLDLEKSRHQIQQTSESFQL 180
FPPLLSGNDFQTVEEGSNVKLVCNVKANPQAQMMWYKNSSLLDLEKSRHQIQQTSESFQL
Sbjct: 121 FPPLLSGNDFQTVEEGSNVKLVCNVKANPQAQMMWYKNSSLLDLEKSRHQIQQTSESFQL 180
Query: 181 SITKVEKPDNGTYSCIAKSSLKTESLDFHLIVKDKTVGVPIEPIIAACVVIFLTLCFGLI 240
SITKVEKPDNGTYSCIAKSSLKTESLDFHLIVKDKTVGVPIEPIIAACVVIFLTLCFGLI
Sbjct: 181 SITKVEKPDNGTYSCIAKSSLKTESLDFHLIVKDKTVGVPIEPIIAACVVIFLTLCFGLI 240
Query: 241 ARRKKIMKLCMKDKDPHSETAL 262
ARRKKIMKLCMKDKDPHSETAL
Sbjct: 241 ARRKKIMKLCMKDKDPHSETAL 262
>gi|115529482 neural cell adhesion molecule 1 isoform 2 [Homo
sapiens]
Length = 858
Score = 66.2 bits (160), Expect = 3e-11
Identities = 52/179 (29%), Positives = 82/179 (45%), Gaps = 13/179 (7%)
Query: 55 AVQNHTREEELLWYREEGRVDLKSGNKINS----SSVCVSSISENDNGISFTCR----LG 106
+ +N + EE+ W R E + L + S SS+ + SI D G + C +G
Sbjct: 344 STRNISSEEKASWTRPEKQETLDGHMVVRSHARVSSLTLKSIQYTDAG-EYICTASNTIG 402
Query: 107 RDQSVSVSVVLNVTFPPLLSGNDFQTVEEGSNVKLVCNVKANPQAQMMWYKNSSLLDLEK 166
+D S S+ L V + P L G EG+ V + C V A P A + W+++ LL
Sbjct: 403 QD---SQSMYLEVQYAPKLQGPVAVYTWEGNQVNITCEVFAYPSATISWFRDGQLLPSSN 459
Query: 167 -SRHQIQQTSESFQLSITKVEKPDNGTYSCIAKSSLKTESLDFHLIVKDKTVGVPIEPI 224
S +I T + L +T + D G Y+C A + + ESL+F L+ D I+ +
Sbjct: 460 YSNIKIYNTPSASYLEVTPDSENDFGNYNCTAVNRIGQESLEFILVQADTPSSPSIDQV 518
Score = 57.4 bits (137), Expect = 1e-08
Identities = 44/177 (24%), Positives = 81/177 (45%), Gaps = 15/177 (8%)
Query: 47 GSQASLICAVQNHTREEELLWYREEGRVDLKSGNK---INSSSVCVSSISENDNGISFTC 103
G A ++C V + + ++W + V LK + ++++ + + I + D G ++ C
Sbjct: 132 GEDAVIVCDVVS-SLPPTIIWKHKGRDVILKKDVRFIVLSNNYLQIRGIKKTDEG-TYRC 189
Query: 104 R-----LGRDQSVSVSVVLNVTFPPLLSGNDF---QTVEEGSNVKLVCNVKANPQAQMMW 155
G + V++NV PP + T G +V LVC+ + P+ M W
Sbjct: 190 EGRILARGEINFKDIQVIVNV--PPTIQARQNIVNATANLGQSVTLVCDAEGFPEPTMSW 247
Query: 156 YKNSSLLDLEKSRHQIQQTSESFQLSITKVEKPDNGTYSCIAKSSLKTESLDFHLIV 212
K+ ++ E+ + + +S QL+I KV+K D Y CIA++ + HL V
Sbjct: 248 TKDGEQIEQEEDDEKYIFSDDSSQLTIKKVDKNDEAEYICIAENKAGEQDATIHLKV 304
Score = 46.2 bits (108), Expect = 3e-05
Identities = 45/190 (23%), Positives = 80/190 (42%), Gaps = 16/190 (8%)
Query: 47 GSQASLICAVQNHTREEELLWYREEGRVDLKSGNKIN-------SSSVCVSSISENDNGI 99
G +C V +++++ W+ G + +I+ SS++ + + + +D GI
Sbjct: 34 GESKFFLCQVAGDAKDKDISWFSPNGEKLTPNQQRISVVWNDDSSSTLTIYNANIDDAGI 93
Query: 100 SFTCRLGRDQSVSVSVVLNVTFPPLLSGN--DFQTVEEGSNVKLVCNVKANPQAQMMWYK 157
G D S S + V F L+ N Q EG + +VC+V ++ ++W
Sbjct: 94 YKCVVTGEDGSESEATVNVKIFQKLMFKNAPTPQEFREGEDAVIVCDVVSSLPPTIIWKH 153
Query: 158 NSSLLDLEKSRHQIQQTSESFQLSITKVEKPDNGTYSCIAKSSLKTESLDFHLIVKDKTV 217
+ L+K I ++ L I ++K D GTY C + + E + KD V
Sbjct: 154 KGRDVILKKDVRFIVLSNN--YLQIRGIKKTDEGTYRCEGRILARGE-----INFKDIQV 206
Query: 218 GVPIEPIIAA 227
V + P I A
Sbjct: 207 IVNVPPTIQA 216
>gi|94420689 neural cell adhesion molecule 1 isoform 1 [Homo
sapiens]
Length = 848
Score = 62.0 bits (149), Expect = 5e-10
Identities = 50/175 (28%), Positives = 84/175 (48%), Gaps = 15/175 (8%)
Query: 55 AVQNHTREEELLWYREEGRVDLKSGNKINSSSVCVSSISENDNGISFTCR----LGRDQS 110
+ +N + EE+ L +G + ++S ++ SS+ + SI D G + C +G+D
Sbjct: 344 STRNISSEEKTL----DGHMVVRSHARV--SSLTLKSIQYTDAG-EYICTASNTIGQD-- 394
Query: 111 VSVSVVLNVTFPPLLSGNDFQTVEEGSNVKLVCNVKANPQAQMMWYKNSSLLDLEK-SRH 169
S S+ L V + P L G EG+ V + C V A P A + W+++ LL S
Sbjct: 395 -SQSMYLEVQYAPKLQGPVAVYTWEGNQVNITCEVFAYPSATISWFRDGQLLPSSNYSNI 453
Query: 170 QIQQTSESFQLSITKVEKPDNGTYSCIAKSSLKTESLDFHLIVKDKTVGVPIEPI 224
+I T + L +T + D G Y+C A + + ESL+F L+ D I+ +
Sbjct: 454 KIYNTPSASYLEVTPDSENDFGNYNCTAVNRIGQESLEFILVQADTPSSPSIDQV 508
Score = 57.4 bits (137), Expect = 1e-08
Identities = 44/177 (24%), Positives = 81/177 (45%), Gaps = 15/177 (8%)
Query: 47 GSQASLICAVQNHTREEELLWYREEGRVDLKSGNK---INSSSVCVSSISENDNGISFTC 103
G A ++C V + + ++W + V LK + ++++ + + I + D G ++ C
Sbjct: 132 GEDAVIVCDVVS-SLPPTIIWKHKGRDVILKKDVRFIVLSNNYLQIRGIKKTDEG-TYRC 189
Query: 104 R-----LGRDQSVSVSVVLNVTFPPLLSGNDF---QTVEEGSNVKLVCNVKANPQAQMMW 155
G + V++NV PP + T G +V LVC+ + P+ M W
Sbjct: 190 EGRILARGEINFKDIQVIVNV--PPTIQARQNIVNATANLGQSVTLVCDAEGFPEPTMSW 247
Query: 156 YKNSSLLDLEKSRHQIQQTSESFQLSITKVEKPDNGTYSCIAKSSLKTESLDFHLIV 212
K+ ++ E+ + + +S QL+I KV+K D Y CIA++ + HL V
Sbjct: 248 TKDGEQIEQEEDDEKYIFSDDSSQLTIKKVDKNDEAEYICIAENKAGEQDATIHLKV 304
Score = 46.2 bits (108), Expect = 3e-05
Identities = 45/190 (23%), Positives = 80/190 (42%), Gaps = 16/190 (8%)
Query: 47 GSQASLICAVQNHTREEELLWYREEGRVDLKSGNKIN-------SSSVCVSSISENDNGI 99
G +C V +++++ W+ G + +I+ SS++ + + + +D GI
Sbjct: 34 GESKFFLCQVAGDAKDKDISWFSPNGEKLTPNQQRISVVWNDDSSSTLTIYNANIDDAGI 93
Query: 100 SFTCRLGRDQSVSVSVVLNVTFPPLLSGN--DFQTVEEGSNVKLVCNVKANPQAQMMWYK 157
G D S S + V F L+ N Q EG + +VC+V ++ ++W
Sbjct: 94 YKCVVTGEDGSESEATVNVKIFQKLMFKNAPTPQEFREGEDAVIVCDVVSSLPPTIIWKH 153
Query: 158 NSSLLDLEKSRHQIQQTSESFQLSITKVEKPDNGTYSCIAKSSLKTESLDFHLIVKDKTV 217
+ L+K I ++ L I ++K D GTY C + + E + KD V
Sbjct: 154 KGRDVILKKDVRFIVLSNN--YLQIRGIKKTDEGTYRCEGRILARGE-----INFKDIQV 206
Query: 218 GVPIEPIIAA 227
V + P I A
Sbjct: 207 IVNVPPTIQA 216
>gi|115529478 neural cell adhesion molecule 1 isoform 3 [Homo
sapiens]
Length = 761
Score = 62.0 bits (149), Expect = 5e-10
Identities = 50/175 (28%), Positives = 84/175 (48%), Gaps = 15/175 (8%)
Query: 55 AVQNHTREEELLWYREEGRVDLKSGNKINSSSVCVSSISENDNGISFTCR----LGRDQS 110
+ +N + EE+ L +G + ++S ++ SS+ + SI D G + C +G+D
Sbjct: 344 STRNISSEEKTL----DGHMVVRSHARV--SSLTLKSIQYTDAG-EYICTASNTIGQD-- 394
Query: 111 VSVSVVLNVTFPPLLSGNDFQTVEEGSNVKLVCNVKANPQAQMMWYKNSSLLDLEK-SRH 169
S S+ L V + P L G EG+ V + C V A P A + W+++ LL S
Sbjct: 395 -SQSMYLEVQYAPKLQGPVAVYTWEGNQVNITCEVFAYPSATISWFRDGQLLPSSNYSNI 453
Query: 170 QIQQTSESFQLSITKVEKPDNGTYSCIAKSSLKTESLDFHLIVKDKTVGVPIEPI 224
+I T + L +T + D G Y+C A + + ESL+F L+ D I+ +
Sbjct: 454 KIYNTPSASYLEVTPDSENDFGNYNCTAVNRIGQESLEFILVQADTPSSPSIDQV 508
Score = 57.4 bits (137), Expect = 1e-08
Identities = 44/177 (24%), Positives = 81/177 (45%), Gaps = 15/177 (8%)
Query: 47 GSQASLICAVQNHTREEELLWYREEGRVDLKSGNK---INSSSVCVSSISENDNGISFTC 103
G A ++C V + + ++W + V LK + ++++ + + I + D G ++ C
Sbjct: 132 GEDAVIVCDVVS-SLPPTIIWKHKGRDVILKKDVRFIVLSNNYLQIRGIKKTDEG-TYRC 189
Query: 104 R-----LGRDQSVSVSVVLNVTFPPLLSGNDF---QTVEEGSNVKLVCNVKANPQAQMMW 155
G + V++NV PP + T G +V LVC+ + P+ M W
Sbjct: 190 EGRILARGEINFKDIQVIVNV--PPTIQARQNIVNATANLGQSVTLVCDAEGFPEPTMSW 247
Query: 156 YKNSSLLDLEKSRHQIQQTSESFQLSITKVEKPDNGTYSCIAKSSLKTESLDFHLIV 212
K+ ++ E+ + + +S QL+I KV+K D Y CIA++ + HL V
Sbjct: 248 TKDGEQIEQEEDDEKYIFSDDSSQLTIKKVDKNDEAEYICIAENKAGEQDATIHLKV 304
Score = 46.2 bits (108), Expect = 3e-05
Identities = 45/190 (23%), Positives = 80/190 (42%), Gaps = 16/190 (8%)
Query: 47 GSQASLICAVQNHTREEELLWYREEGRVDLKSGNKIN-------SSSVCVSSISENDNGI 99
G +C V +++++ W+ G + +I+ SS++ + + + +D GI
Sbjct: 34 GESKFFLCQVAGDAKDKDISWFSPNGEKLTPNQQRISVVWNDDSSSTLTIYNANIDDAGI 93
Query: 100 SFTCRLGRDQSVSVSVVLNVTFPPLLSGN--DFQTVEEGSNVKLVCNVKANPQAQMMWYK 157
G D S S + V F L+ N Q EG + +VC+V ++ ++W
Sbjct: 94 YKCVVTGEDGSESEATVNVKIFQKLMFKNAPTPQEFREGEDAVIVCDVVSSLPPTIIWKH 153
Query: 158 NSSLLDLEKSRHQIQQTSESFQLSITKVEKPDNGTYSCIAKSSLKTESLDFHLIVKDKTV 217
+ L+K I ++ L I ++K D GTY C + + E + KD V
Sbjct: 154 KGRDVILKKDVRFIVLSNN--YLQIRGIKKTDEGTYRCEGRILARGE-----INFKDIQV 206
Query: 218 GVPIEPIIAA 227
V + P I A
Sbjct: 207 IVNVPPTIQA 216
>gi|20127422 Down syndrome cell adhesion molecule isoform CHD2-42
precursor [Homo sapiens]
Length = 2012
Score = 60.5 bits (145), Expect = 1e-09
Identities = 52/167 (31%), Positives = 81/167 (48%), Gaps = 18/167 (10%)
Query: 47 GSQASLICAVQNHTREEELLWYREEGRVDLKSGNK-----INSSSVCVSSISENDNGISF 101
GSQ SL C+V T ++EL WYR G + L G IN ++ + + ++D G ++
Sbjct: 328 GSQVSLSCSVTG-TEDQELSWYRN-GEI-LNPGKNVRITGINHENLIMDHMVKSDGG-AY 383
Query: 102 TCRLGRDQSVS---VSVVLNVTFPPLLSGNDFQTVEEGSNVKLVCNVKANPQAQMMWYKN 158
C + +D+ + V VVL P ++S + V V L+CNVK P + W +
Sbjct: 384 QCFVRKDKLSAQDYVQVVLEDGTPKIISAFSEKVVSPAEPVSLMCNVKGTPLPTITWTLD 443
Query: 159 SSLLDLEKSRHQIQQ--TSES---FQLSITKVEKPDNGTYSCIAKSS 200
+ L+ H+I Q TSE L+I+ + D G Y C A +S
Sbjct: 444 DDPI-LKGGSHRISQMITSEGNVVSYLNISSSQVRDGGVYRCTANNS 489
Score = 40.4 bits (93), Expect = 0.002
Identities = 41/183 (22%), Positives = 71/183 (38%), Gaps = 19/183 (10%)
Query: 44 TTPGSQASLICAVQNHTREEELLWYREEGRVDLKSGNKI---NSSSVCVSSISENDNGIS 100
T G+ A C + + + E+ V L SG++ ++ ++ + + D +
Sbjct: 135 TMRGNVAVFKCIIPSSVEAYITVVSWEKDTVSLVSGSRFLITSTGALYIKDVQNEDGLYN 194
Query: 101 FTC----------RLGRDQSVSVSVVLNVTFPPLLSGNDFQTVEEGSNVKLVCNVKANPQ 150
+ C R + VS N + P +L G D + G V+L C +P+
Sbjct: 195 YRCITRHRYTGETRQSNSARLFVSDPAN-SAPSILDGFDHRKAMAGQRVELPCKALGHPE 253
Query: 151 AQMMWYKNSSLLDLEKSRHQIQQTSESFQLSITKVEKPDNGTYSCIAKSSLKTESLDFHL 210
W K++ L+L R Q T L I + D+G+Y C + T + L
Sbjct: 254 PDYRWLKDNMPLEL-SGRFQKTVTG----LLIENIRPSDSGSYVCEVSNRYGTAKVIGRL 308
Query: 211 IVK 213
VK
Sbjct: 309 YVK 311
Score = 40.0 bits (92), Expect = 0.002
Identities = 46/183 (25%), Positives = 74/183 (40%), Gaps = 21/183 (11%)
Query: 45 TPGSQASLICAVQNHTREEELLWYREEGRVDLKSGNKINSSSVC----------VSSISE 94
+P SL+C V+ T + W ++ + LK G+ S + +SS
Sbjct: 419 SPAEPVSLMCNVKG-TPLPTITWTLDDDPI-LKGGSHRISQMITSEGNVVSYLNISSSQV 476
Query: 95 NDNGISFTCRLGRDQSVSV-SVVLNVTFPPLLSGNDFQTVEEGSNVKLVCNVKANPQAQM 153
D G+ + C V + +NV P + T G + + C V P +
Sbjct: 477 RDGGV-YRCTANNSAGVVLYQARINVRGPASIRPMKNITAIAGRDTYIHCRVIGYPYYSI 535
Query: 154 MWYKNSSLLDLEKSRHQIQQTSESFQLSITKVEKP-DNGTYSC--IAKSSLKTESLDFHL 210
WYKNS+LL H+ + L ++ V+K D G Y+C + + L T S H+
Sbjct: 536 KWYKNSNLLPF---NHRQVAFENNGTLKLSDVQKEVDEGEYTCNVLVQPQLST-SQSVHV 591
Query: 211 IVK 213
VK
Sbjct: 592 TVK 594
Score = 33.9 bits (76), Expect = 0.15
Identities = 33/136 (24%), Positives = 57/136 (41%), Gaps = 8/136 (5%)
Query: 83 NSSSVCVSSISENDNGISFTCRL--GRDQSVSVSVVLNVTFPPLLSGNDFQTVEEGSNVK 140
N+ ++ +S + + + +TC + S S SV + V PP + +F G V
Sbjct: 555 NNGTLKLSDVQKEVDEGEYTCNVLVQPQLSTSQSVHVTVKVPPFIQPFEFPRFSIGQRVF 614
Query: 141 LVCNVKANP-QAQMMWYKNSSLL--DLEKSRHQIQQTSESFQLSITKVEKPDNGTYSCIA 197
+ C V + + W K+ + L + I TS L I+ + NG Y+CIA
Sbjct: 615 IPCVVVSGDLPITITWQKDGRPIPGSLGVTIDNIDFTSS---LRISNLSLMHNGNYTCIA 671
Query: 198 KSSLKTESLDFHLIVK 213
++ LIV+
Sbjct: 672 RNEAAAVEHQSQLIVR 687
Score = 31.6 bits (70), Expect = 0.73
Identities = 29/114 (25%), Positives = 53/114 (46%), Gaps = 10/114 (8%)
Query: 106 GRDQSVSVSVVLNVTFPP--LLSGNDFQTVEEGSNVKLVCNVKANPQAQMMWYKNS---- 159
GR S + V + P +L+ + T ++ L C +P + W K+S
Sbjct: 1268 GRGNSSEIITVEPLAKAPARILTFSGTVTTPWMKDIVLPCKAVGDPSPAVKWMKDSNGTP 1327
Query: 160 SLLDLEKSRHQIQQTSESFQLSITKVEKPDNGTYSCIAKSSLKTESLDFHLIVK 213
SL+ ++ R ++ SF + K E D+G YSCIA ++ ++ + +L V+
Sbjct: 1328 SLVTIDGRRSIF--SNGSFIIRTVKAE--DSGYYSCIANNNWGSDEIILNLQVQ 1377
>gi|190358524 follistatin-like 5 isoform c [Homo sapiens]
Length = 837
Score = 57.8 bits (138), Expect = 1e-08
Identities = 47/179 (26%), Positives = 81/179 (45%), Gaps = 8/179 (4%)
Query: 41 ILDTTPGSQASLICAVQNHTREEELLWYREE---GRVDLKSGNKI-NSSSVCVSSISEND 96
I T G A L CA+Q T ++W R +DL+ N + S+ ++ ++
Sbjct: 256 ITAATVGQSAVLSCAIQG-TLRPPIIWKRNNIILNNLDLEDINDFGDDGSLYITKVTTTH 314
Query: 97 NGISFTCRLGRDQSVSVSVVLNVTFPPLLSGN-DFQTVEEGSNVKLVCNVKANPQAQMMW 155
G ++TC + V + + V PP++ + Q E G L C+ + P+ Q+ W
Sbjct: 315 VG-NYTCYADGYEQVYQTHIFQVNVPPVIRVYPESQAREPGVTASLRCHAEGIPKPQLGW 373
Query: 156 YKNSSLLDLEKSRHQIQQTSESFQLSITKVEKPDNGTYSCIAKSSLKTESLDFHLIVKD 214
KN + + S+ Q + S ++ I+ V D G Y+CIAK+ + L V+D
Sbjct: 374 LKNGIDITPKLSKQLTLQANGS-EVHISNVRYEDTGAYTCIAKNEAGVDEDISSLFVED 431
>gi|190358522 follistatin-like 5 isoform b [Homo sapiens]
Length = 846
Score = 57.8 bits (138), Expect = 1e-08
Identities = 47/179 (26%), Positives = 81/179 (45%), Gaps = 8/179 (4%)
Query: 41 ILDTTPGSQASLICAVQNHTREEELLWYREE---GRVDLKSGNKI-NSSSVCVSSISEND 96
I T G A L CA+Q T ++W R +DL+ N + S+ ++ ++
Sbjct: 256 ITAATVGQSAVLSCAIQG-TLRPPIIWKRNNIILNNLDLEDINDFGDDGSLYITKVTTTH 314
Query: 97 NGISFTCRLGRDQSVSVSVVLNVTFPPLLSGN-DFQTVEEGSNVKLVCNVKANPQAQMMW 155
G ++TC + V + + V PP++ + Q E G L C+ + P+ Q+ W
Sbjct: 315 VG-NYTCYADGYEQVYQTHIFQVNVPPVIRVYPESQAREPGVTASLRCHAEGIPKPQLGW 373
Query: 156 YKNSSLLDLEKSRHQIQQTSESFQLSITKVEKPDNGTYSCIAKSSLKTESLDFHLIVKD 214
KN + + S+ Q + S ++ I+ V D G Y+CIAK+ + L V+D
Sbjct: 374 LKNGIDITPKLSKQLTLQANGS-EVHISNVRYEDTGAYTCIAKNEAGVDEDISSLFVED 431
>gi|190358520 follistatin-like 5 isoform a [Homo sapiens]
Length = 847
Score = 57.8 bits (138), Expect = 1e-08
Identities = 47/179 (26%), Positives = 81/179 (45%), Gaps = 8/179 (4%)
Query: 41 ILDTTPGSQASLICAVQNHTREEELLWYREE---GRVDLKSGNKI-NSSSVCVSSISEND 96
I T G A L CA+Q T ++W R +DL+ N + S+ ++ ++
Sbjct: 257 ITAATVGQSAVLSCAIQG-TLRPPIIWKRNNIILNNLDLEDINDFGDDGSLYITKVTTTH 315
Query: 97 NGISFTCRLGRDQSVSVSVVLNVTFPPLLSGN-DFQTVEEGSNVKLVCNVKANPQAQMMW 155
G ++TC + V + + V PP++ + Q E G L C+ + P+ Q+ W
Sbjct: 316 VG-NYTCYADGYEQVYQTHIFQVNVPPVIRVYPESQAREPGVTASLRCHAEGIPKPQLGW 374
Query: 156 YKNSSLLDLEKSRHQIQQTSESFQLSITKVEKPDNGTYSCIAKSSLKTESLDFHLIVKD 214
KN + + S+ Q + S ++ I+ V D G Y+CIAK+ + L V+D
Sbjct: 375 LKNGIDITPKLSKQLTLQANGS-EVHISNVRYEDTGAYTCIAKNEAGVDEDISSLFVED 432
>gi|5031927 skeletal muscle receptor tyrosine kinase [Homo sapiens]
Length = 869
Score = 57.4 bits (137), Expect = 1e-08
Identities = 47/159 (29%), Positives = 74/159 (46%), Gaps = 10/159 (6%)
Query: 50 ASLICAVQNHTREEELLWYREEGRV---DLKSGNKINSSSVCVSSISENDNGI-SFTCRL 105
A+ +CAV+++ + E+ W R + + D + + N + + S+ ++D+GI T
Sbjct: 45 ATFMCAVESYP-QPEISWTRNKILIKLFDTRYSIRENGQLLTILSVEDSDDGIYCCTANN 103
Query: 106 GRDQSVSVSVVLNVTFPPLLSGNDFQT-VEEGSNVKLVCNVKANPQAQMMWYKNSSLLDL 164
G +V L V P ++ + EG L C NP+ + W K S L
Sbjct: 104 GVGGAVESCGALQVKMKPKITRPPINVKIIEGLKAVLPCTTMGNPKPSVSWIKGDSPLR- 162
Query: 165 EKSRHQIQQTSESFQLSITKVEKPDNGTYSCIAKSSLKT 203
E SR + ES L I V+K D G Y C+AK+SL T
Sbjct: 163 ENSRIAVL---ESGSLRIHNVQKEDAGQYRCVAKNSLGT 198
>gi|126517478 peroxidasin homolog-like [Homo sapiens]
Length = 1463
Score = 55.8 bits (133), Expect = 4e-08
Identities = 47/175 (26%), Positives = 75/175 (42%), Gaps = 8/175 (4%)
Query: 47 GSQASLICAVQNHTREEELLWYREEGRVDLKSGNKINSSSVCVSSISENDNGISFTCRLG 106
G+ +L C H + W R+ G S + SS + + +I++ D+G FTC
Sbjct: 344 GTSTTLECMATGHPHPL-ITWTRDNGLELDGSRHVATSSGLYLQNITQRDHG-RFTCHAN 401
Query: 107 RDQ-SVSVSVVLNVTFPPLLSGNDF-QTVEEGSNVKLVCNVKANPQAQMMWYKNSSLLDL 164
+V + + V PP + Q V E V+ +C NP ++W K L +
Sbjct: 402 NSHGTVQAAANIIVQAPPQFTVTPKDQVVLEEHAVEWLCEADGNPPPVIVWTKTGGQLPV 461
Query: 165 EKSRHQIQQTSESFQLSITKVEKPDNGTYSCIAKSSLKTESLDFHLIVKDKTVGV 219
E +H + + L I + + D G Y C A SSL + + L VK K + V
Sbjct: 462 E-GQHTVLSSGT---LRIDRAAQHDQGQYECQAVSSLGVKKVSVQLTVKPKALAV 512
Score = 42.0 bits (97), Expect = 5e-04
Identities = 23/76 (30%), Positives = 36/76 (47%), Gaps = 5/76 (6%)
Query: 133 VEEGSNVKLVCNVKANPQAQMMWYKNSSLLDLEKSRHQIQQTSESFQLSITKVEKPDNGT 192
V G+ V C + NP+ +++W N+ LDLE + L I + D G
Sbjct: 245 VPSGNTVYFTCRAEGNPKPEIIWIHNNHSLDLEDDTR--LNVFDDGTLMIRNTRESDQGV 302
Query: 193 YSCIAKSS---LKTES 205
Y C+A++S KT+S
Sbjct: 303 YQCMARNSAGEAKTQS 318
Score = 40.8 bits (94), Expect = 0.001
Identities = 33/141 (23%), Positives = 60/141 (42%), Gaps = 10/141 (7%)
Query: 65 LLWYREEGRVDLKSGNKINSSSVC-VSSISENDNGISFTCRLGRDQSVS-VSVVLNVTFP 122
++W + G++ ++ + + SS + +++D G + C+ V VSV L V
Sbjct: 450 IVWTKTGGQLPVEGQHTVLSSGTLRIDRAAQHDQG-QYECQAVSSLGVKKVSVQLTVKPK 508
Query: 123 PLLSGNDFQ---TVEEGSNVKLVCNVKANPQAQMMWYKNSSLLDLEKSRHQIQQTSESFQ 179
L +VE G N+ + C+ + PQ + W K + H +
Sbjct: 509 ALAVFTQLPQDTSVEVGKNINISCHAQGEPQPIITWNKEGVQITESGKFH----VDDEGT 564
Query: 180 LSITKVEKPDNGTYSCIAKSS 200
L+I PD G Y C+A++S
Sbjct: 565 LTIYDAGFPDQGRYECVARNS 585
>gi|110431348 deleted in colorectal carcinoma [Homo sapiens]
Length = 1447
Score = 55.5 bits (132), Expect = 5e-08
Identities = 45/170 (26%), Positives = 78/170 (45%), Gaps = 10/170 (5%)
Query: 47 GSQASLICAVQNHTREEELLWYREEGRVDLKSG--NKINSSSVCVSSISENDNGISFTCR 104
G A L C V + W R E + L+S + + S++ +S+++++D+G+ +TC
Sbjct: 254 GKDAVLECCVSGYP-PPSFTWLRGEEVIQLRSKKYSLLGGSNLLISNVTDDDSGM-YTCV 311
Query: 105 LG-RDQSVSVSVVLNVTFPP-LLSGNDFQTVEEGSNVKLVCNVKANPQAQMMWYKNSSLL 162
+ +++++S S L V PP L+ E +++ C V P + W KN ++
Sbjct: 312 VTYKNENISASAELTVLVPPWFLNHPSNLYAYESMDIEFECTVSGKPVPTVNWMKNGDVV 371
Query: 163 DLEKSRHQIQQTSESFQLSITKVEKPDNGTYSCIAKSSLKTESLDFHLIV 212
+ QI S L I V K D G Y C+A++ LIV
Sbjct: 372 -IPSDYFQIVGGS---NLRILGVVKSDEGFYQCVAENEAGNAQTSAQLIV 417
Score = 32.7 bits (73), Expect = 0.33
Identities = 16/62 (25%), Positives = 27/62 (43%), Gaps = 3/62 (4%)
Query: 135 EGSNVKLVCNVKANPQAQMMWYKNSSLLDLEKSRHQIQQTSESFQLSITKVEKPDNGTYS 194
EG + L C V P W + ++ L ++ + S L I+ V D+G Y+
Sbjct: 253 EGKDAVLECCVSGYPPPSFTWLRGEEVIQLRSKKYSLLGGS---NLLISNVTDDDSGMYT 309
Query: 195 CI 196
C+
Sbjct: 310 CV 311
Score = 30.0 bits (66), Expect = 2.1
Identities = 37/168 (22%), Positives = 66/168 (39%), Gaps = 14/168 (8%)
Query: 44 TTPGSQASLICAVQNHTREEELLWYREEGRVDL---KSGNKINSSSVCVSSISEN----- 95
T G L C+ ++ + W ++ + L + ++++ S+ + +I +
Sbjct: 51 TMRGGNVLLDCSAESDRGVPVIKWKKDGIHLALGMDERKQQLSNGSLLIQNILHSRHHKP 110
Query: 96 DNGISFTCR--LGRDQSVSVSVVLNVTFPPL--LSGNDFQTVEEGSNVKLVCNVKANPQA 151
D G+ + C LG S+ PL LS + T G V L C V P
Sbjct: 111 DEGL-YQCEASLGDSGSIISRTAKVAVAGPLRFLSQTESVTAFMGDTVLLKCEVIGEPMP 169
Query: 152 QMMWYKNSSLLDLEKSRHQIQQTSESFQLSITKVEKPDNGTYSCIAKS 199
+ W KN L ++ S L I++++ D G Y C A++
Sbjct: 170 TIHWQKNQQDLTPIPGDSRV-VVLPSGALQISRLQPGDIGIYRCSARN 216
>gi|169177000 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 3783
Score = 55.5 bits (132), Expect = 5e-08
Identities = 37/118 (31%), Positives = 64/118 (54%), Gaps = 14/118 (11%)
Query: 90 SSISENDNGISFTC----RLGRDQSVSVSVVLNVTFPPLLSGNDFQTVEE--GSNVKLVC 143
+++S D+G ++ C R+GR Q+VS ++V P+L G F + E G +++L C
Sbjct: 2903 AAVSREDSG-TYVCWAENRVGRTQAVSF---VHVKEAPVLQGEAFSYLVEPVGGSIQLDC 2958
Query: 144 NVKANPQAQMMWYKNSSLLDLEKSRHQIQQTSESFQLSITKVEKPDNGTYSCIAKSSL 201
V+ +P + W K+ L RHQ+Q S L+I + E+ D G Y C+A++ +
Sbjct: 2959 VVRGDPVPDIHWIKDGLPLRGSHLRHQLQNGS----LTIRRTERDDAGRYQCLAENEM 3012
Score = 50.4 bits (119), Expect = 2e-06
Identities = 47/179 (26%), Positives = 76/179 (42%), Gaps = 15/179 (8%)
Query: 42 LDTTPGSQASLICAVQNHTREEELLWYREEGRVDLKSGNKINSS--SVCVSSISENDNGI 99
L + PG +++C V+ + + W ++ + L ++ S ++ +S + D GI
Sbjct: 2041 LVSRPGELVTMVCPVRG-SPPIHVSWLKDGLPLPLSQRTLLHGSGHTLRISKVQLADAGI 2099
Query: 100 SFTCRLGRDQSVSV-SVVLNVTFPPLLSGNDFQT---VEEGSNVKLVCNVKANPQAQMMW 155
FTC V+ + L V PP+L +FQ V GS V+L C + P + W
Sbjct: 2100 -FTCVAASPAGVADRNFTLQVQVPPVLEPVEFQNDVVVVRGSLVELPCEARGVPLPLVSW 2158
Query: 156 YKNSSLLDLEKSRHQIQQTSESFQLSITKVEKPDNGTYSCIAKSSLKTESLDFHLIVKD 214
K+ L Q + L + V D+GTYSC+A S F L V +
Sbjct: 2159 MKDGEPL-------LSQSLEQGPSLQLEAVGAGDSGTYSCVAVSEAGEARRHFQLTVME 2210
Score = 46.6 bits (109), Expect = 2e-05
Identities = 34/120 (28%), Positives = 57/120 (47%), Gaps = 8/120 (6%)
Query: 82 INSSSVCVSSISENDNGISFTCRLGRDQSVSVSVV--LNVTFPPLLSGNDFQTVEE--GS 137
+ V S +E + S+ C + +Q+ S + L V PP ++G D + V S
Sbjct: 1613 LEDGQVLQVSTAEVADAASYMC-VAENQAGSAEKLFTLRVQVPPRIAGLDLEQVTAILNS 1671
Query: 138 NVKLVCNVKANPQAQMMWYKNSSLLDLEKSRHQIQQTSESFQLSITKVEKPDNGTYSCIA 197
+V L C+V A+P ++ WYK+S L L + + T L + + D+G Y+C A
Sbjct: 1672 SVSLPCDVHAHPNPEVTWYKDSQALSLGEEVFLLPGT---HTLQLGRARLSDSGMYTCEA 1728
Score = 46.2 bits (108), Expect = 3e-05
Identities = 47/176 (26%), Positives = 76/176 (43%), Gaps = 27/176 (15%)
Query: 48 SQASLICAVQNHTREEELLWYREEGRVDLKSGNKI----NSSSVCVSSISENDNGISFTC 103
S SL C V H E + WY++ + L G ++ + ++ + +D+G+ +TC
Sbjct: 1671 SSVSLPCDVHAHPNPE-VTWYKDSQALSL--GEEVFLLPGTHTLQLGRARLSDSGM-YTC 1726
Query: 104 RL----GRDQSVSVSVVLNVTFPPLL-----SGNDFQTVEEGSNVKLVCNVKANPQAQMM 154
GRDQ + V L+V PP D V G L C A P+ +
Sbjct: 1727 EALNAAGRDQKL---VQLSVLVPPAFRQAPRGPQDAVLVRVGDKAVLSCETDALPEPTVT 1783
Query: 155 WYKNSSLLDLEKSRHQIQQTSESFQLSITKVEKPDNGTYSC----IAKSSLKTESL 206
WYK+ L L + + Q +L I + + D G YSC +A +++T +L
Sbjct: 1784 WYKDGQPLVLAQ---RTQALRGGQRLEIQEAQVSDKGLYSCKVSNVAGEAVRTFTL 1836
Score = 46.2 bits (108), Expect = 3e-05
Identities = 40/173 (23%), Positives = 78/173 (45%), Gaps = 14/173 (8%)
Query: 42 LDTTPGSQASLICAVQNHTREEELLWYREEGRVDLKSGNKINSSSVCVSSISENDNGISF 101
L TPG+ L+C Q T + + W++ D ++ ++ ++S + D G+ +
Sbjct: 2223 LSLTPGAPMELLCDAQG-TPQPNITWHK-----DGQALTRLENNSRATRVLRVRDAGL-Y 2275
Query: 102 TCRLGRDQ-SVSVSVVLNVTFPPLLSGNDFQTVEEG---SNVKLVCNVKANPQAQMMWYK 157
TC ++ S + V PP + G G + L C+V+A P ++ W++
Sbjct: 2276 TCLAESPAGAIEKSFRVRVQAPPNIVGPRGPRFVVGLAPGQLVLECSVEAEPAPKITWHR 2335
Query: 158 NSSLLDLEKSRHQIQQTSESFQLSITKVEKPDNGTYSCIAKSSLKTESLDFHL 210
+ +L E + Q + QL + D+G YSC A+++ + S+ F +
Sbjct: 2336 DGIVLQ-EDAHTQFPERGRFLQLQA--LSTADSGDYSCTARNAAGSTSVAFRV 2385
Score = 45.8 bits (107), Expect = 4e-05
Identities = 41/183 (22%), Positives = 78/183 (42%), Gaps = 18/183 (9%)
Query: 41 ILDTTPGSQASLICAVQNHTREEELLWYREEGRVDLKSGNKINSSSVCVSSISENDNGIS 100
++ G A L+C V H + +L W+++ + + I+ V + + N +
Sbjct: 1172 VIKVLDGQTAHLMCNVTGHP-QPKLTWFKDGRPLARGDAHHISPDGVLLQVLQANLSSAG 1230
Query: 101 -FTCRLG-----RDQSVSVSVVLNVTFPPLLSGNDFQTVEE-----GSNVKLVCNVKANP 149
++C + + +SV+L P +L G + EE + + L+C A P
Sbjct: 1231 HYSCIAANAVGEKTKHFQLSVLLA---PTILGGAEDSADEEVTVTVNNPISLICEALAFP 1287
Query: 150 QAQMMWYKNSSLLDLEKSRHQIQQTSESFQLSITKVEKPDNGTYSCIAKSSLKTESLDFH 209
+ W K+ + E SR+ IQ + L I +K D G Y+C+ + L ++H
Sbjct: 1288 SPNITWMKDGA--PFEASRN-IQLLPGTHGLQILNAQKEDAGQYTCVVTNELGEAVKNYH 1344
Query: 210 LIV 212
+ V
Sbjct: 1345 VEV 1347
Score = 45.8 bits (107), Expect = 4e-05
Identities = 49/216 (22%), Positives = 90/216 (41%), Gaps = 22/216 (10%)
Query: 16 LLVILFLPREMTSSVLTVNGKTENYILDTTPGSQASLICAVQNHTREEELLWYREEGRVD 75
++ +L PR +S V E+++L+ G + L C ++ W ++ +
Sbjct: 1927 VVAVLVAPRIRSSGVAR-----EHHVLE---GQEVRLDCEADGQP-PPDVAWLKDGSPLG 1977
Query: 76 LKSGNKI----NSSSVCVSSISENDNGISFTCRLGRDQSVSVSV-VLNVTFPPLLS---- 126
G + + S+ + + +D G ++TC + +NV PP +
Sbjct: 1978 QDMGPHLRFYLDGGSLVLKGLRASDAG-AYTCVAHNPAGEDARLHTVNVLVPPTIKQGAD 2036
Query: 127 GNDFQTVEEGSNVKLVCNVKANPQAQMMWYKNSSLLDLEKSRHQIQQTSESFQLSITKVE 186
G+ G V +VC V+ +P + W K+ L L S+ + S L I+KV+
Sbjct: 2037 GSGTLVSRPGELVTMVCPVRGSPPIHVSWLKDG--LPLPLSQRTLLHGS-GHTLRISKVQ 2093
Query: 187 KPDNGTYSCIAKSSLKTESLDFHLIVKDKTVGVPIE 222
D G ++C+A S +F L V+ V P+E
Sbjct: 2094 LADAGIFTCVAASPAGVADRNFTLQVQVPPVLEPVE 2129
Score = 45.1 bits (105), Expect = 6e-05
Identities = 29/127 (22%), Positives = 54/127 (42%), Gaps = 6/127 (4%)
Query: 89 VSSISENDNGISFTCRLGRDQSVSVSVVLNVTFPPLLSGNDFQTVE---EGSNVKLVCNV 145
++ E D+G+ + + V PP + D + V +G L+CNV
Sbjct: 1128 MTQTQEQDSGLYSCLASNEAGEARRNFSVEVLVPPSIENEDLEEVIKVLDGQTAHLMCNV 1187
Query: 146 KANPQAQMMWYKNSSLLDLEKSRHQIQQTSESFQLSITKVEKPDNGTYSCIAKSSLKTES 205
+PQ ++ W+K+ L + H + + L + + G YSCIA +++ ++
Sbjct: 1188 TGHPQPKLTWFKDGRPLARGDAHH---ISPDGVLLQVLQANLSSAGHYSCIAANAVGEKT 1244
Query: 206 LDFHLIV 212
F L V
Sbjct: 1245 KHFQLSV 1251
Score = 44.3 bits (103), Expect = 1e-04
Identities = 42/174 (24%), Positives = 77/174 (44%), Gaps = 16/174 (9%)
Query: 64 ELLWYREEGRVDLKSGNKIN---SSSVCVSSISENDNGISFTCRLGRDQSVS-VSVVLNV 119
+L WYRE+ L +G++++ V + +N ++C+ + + L V
Sbjct: 1499 DLTWYREDQ--PLSAGDEVSVLQGGRVLQIPLVRAENAGRYSCKASNEVGEDWLHYELLV 1556
Query: 120 TFPPLLSGNDFQTVEE-----GSNVKLVCNVKANPQAQMMWYKNSSLLDLEKSRHQIQQT 174
PP++ G+ + VEE S V L C NP + W +N L R Q+ +
Sbjct: 1557 LTPPVILGDTEELVEEVTVNASSTVSLQCPALGNPVPTISWLQN-GLPFSPSPRLQVLED 1615
Query: 175 SESFQLSITKVEKPDNGTYSCIAKSSLKTESLDFHLIVK--DKTVGVPIEPIIA 226
+ Q+S +V D +Y C+A++ + F L V+ + G+ +E + A
Sbjct: 1616 GQVLQVSTAEV--ADAASYMCVAENQAGSAEKLFTLRVQVPPRIAGLDLEQVTA 1667
Score = 43.9 bits (102), Expect = 1e-04
Identities = 40/176 (22%), Positives = 78/176 (44%), Gaps = 20/176 (11%)
Query: 47 GSQASLICAVQNHTREEELLWYRE-------EGRVDLKSGNKINSSSVCVSSISENDNGI 99
G +A L C + E + WY++ + L+ G ++ VS D G+
Sbjct: 1765 GDKAVLSCET-DALPEPTVTWYKDGQPLVLAQRTQALRGGQRLEIQEAQVS-----DKGL 1818
Query: 100 SFTCRLGRDQSVSV-SVVLNVTFPPLLSGNDFQTVEE--GSNVKLVCNVKANPQAQMMWY 156
++C++ +V + L V PP +TV + GS + L C+V P + W
Sbjct: 1819 -YSCKVSNVAGEAVRTFTLTVQVPPTFENPKTETVSQVAGSPLVLTCDVSGVPAPTVTWL 1877
Query: 157 KNSSLLDLEKSRHQIQQTSESFQLSITKVEKPDNGTYSCIAKSSLKTESLDFHLIV 212
K+ ++ + H + S +L +++++ GTY+C+A+++ DF + V
Sbjct: 1878 KDRMPVE-SSAVHGV--VSRGGRLQLSRLQPAQAGTYTCVAENTQAEARKDFVVAV 1930
Score = 42.7 bits (99), Expect = 3e-04
Identities = 27/98 (27%), Positives = 47/98 (47%), Gaps = 6/98 (6%)
Query: 117 LNVTFPPLLSGN--DFQTVEEGSNVKLVCNVKANPQAQMMWYKNSSLLDLEKSRHQIQQT 174
L V PP++ D T E GS+ L C + +P+ + W K+ + + + IQ +
Sbjct: 2750 LVVQVPPVIENGLPDLSTTE-GSHAFLPCKARGSPEPNITWDKDGQPVSGAEGKFTIQPS 2808
Query: 175 SESFQLSITKVEKPDNGTYSCIAKSSLKTESLDFHLIV 212
E L + +E D GTY+C A++++ HL +
Sbjct: 2809 GE---LLVKNLEGQDAGTYTCTAENAVGRARRRVHLTI 2843
Score = 40.0 bits (92), Expect = 0.002
Identities = 22/91 (24%), Positives = 44/91 (48%), Gaps = 16/91 (17%)
Query: 136 GSNVKLVCNVKANPQAQMMWYKNSSLLDL--------------EKSRHQIQQTSESFQLS 181
G ++ L C+ P +++W K++ L+ + + H++ +S L
Sbjct: 33 GQSLTLECDANGFPVPEIVWLKDAQLVGVPLGWAGYGWDLGWGQVGGHRLLDEGQS--LH 90
Query: 182 ITKVEKPDNGTYSCIAKSSLKTESLDFHLIV 212
++++ D+G YSC A++ T DFHL+V
Sbjct: 91 FPRIQEGDSGLYSCRAENQAGTAQRDFHLLV 121
Score = 40.0 bits (92), Expect = 0.002
Identities = 44/195 (22%), Positives = 81/195 (41%), Gaps = 22/195 (11%)
Query: 33 VNGKTENYILDTTPGSQASLICAVQNHTREEELLWYREEGRVDLKSGN---KINSSSVCV 89
+ G+ +Y+++ GS L C V+ ++ W ++ + L+ + ++ + S+ +
Sbjct: 2938 LQGEAFSYLVEPVGGS-IQLDCVVRGDP-VPDIHWIKDG--LPLRGSHLRHQLQNGSLTI 2993
Query: 90 SSISENDNGISFTCRLGRDQSVSVSVVLNVTFPPLLSGNDFQ------TVEEGSNVKLVC 143
+D G + C + V+ VV+ V L S FQ TV G +V L C
Sbjct: 2994 RRTERDDAG-RYQCLAENEMGVAKKVVILV----LQSAPVFQVEPQDMTVRSGDDVALRC 3048
Query: 144 NVKANPQAQMMWYKNSSLLDLEKSRHQIQQTSESFQLSITKVEKPDNGTYSCIAKSSLKT 203
P + W + L + + S L + VE D GTY C+A + L +
Sbjct: 3049 QATGEPTPTIEWLQAGQPLRASRRLRTLPDGS----LWLENVETGDAGTYDCVAHNLLGS 3104
Query: 204 ESLDFHLIVKDKTVG 218
+ L+V+ + G
Sbjct: 3105 ATARAFLVVRGEPQG 3119
Score = 39.7 bits (91), Expect = 0.003
Identities = 28/100 (28%), Positives = 44/100 (44%), Gaps = 5/100 (5%)
Query: 113 VSVVLNVTFPPLLSGNDFQTVEEGSNVKLVCNVKANPQAQMMWYKNSSLLDLEKSRHQIQ 172
V+V +T PP L G V + V+L CN P +MW K+ + + +Q
Sbjct: 691 VNVPPRITLPPSLPG----PVLVNTPVRLTCNATGAPSPTLMWLKDGNPVS-PAGTPGLQ 745
Query: 173 QTSESFQLSITKVEKPDNGTYSCIAKSSLKTESLDFHLIV 212
L++ D+G YSC+A S++ + D L V
Sbjct: 746 VFPGGRVLTLASARASDSGRYSCVAVSAVGEDRQDVVLQV 785
Score = 37.7 bits (86), Expect = 0.010
Identities = 35/125 (28%), Positives = 55/125 (44%), Gaps = 7/125 (5%)
Query: 92 ISENDNGISFTCRLGRDQSVSVSV--VLNVTFPPLLSGNDFQTVE--EGSNVKLVCNVKA 147
I E D+G+ ++CR + +L +T P +L Q V G++V+L C
Sbjct: 94 IQEGDSGL-YSCRAENQAGTAQRDFHLLVLTPPSVLGAGAAQEVLGLAGADVELQCWTSG 152
Query: 148 NPQAQMMWYKNSSLLDLEKSRHQIQQTSESFQLSITKVEKPDNGTYSCIAKSSLKTESLD 207
P Q+ W K+ + Q+Q+ + L IT D G Y C+A S ++ D
Sbjct: 153 VPTPQVEWTKDRQPVLPGGPHLQVQEDGQV--LRITGSHVGDEGRYQCVAFSPAGQQARD 210
Query: 208 FHLIV 212
F L V
Sbjct: 211 FQLRV 215
Score = 37.7 bits (86), Expect = 0.010
Identities = 23/88 (26%), Positives = 43/88 (48%), Gaps = 6/88 (6%)
Query: 117 LNVTFPPLLSGNDFQ---TVEEGSNVKLVCNVKANPQAQMMWYKNSSLLDLEKSRHQIQQ 173
L V PP + G++ V E V+L+C + P + W+K+ +LL + ++
Sbjct: 213 LRVHAPPTIWGSNETGEVAVMEDHLVQLLCEARGVPTPNITWFKDGALL---PTSTKVVY 269
Query: 174 TSESFQLSITKVEKPDNGTYSCIAKSSL 201
T QL + + + D G Y+C A +++
Sbjct: 270 TRGGRQLQLGRAQSSDAGVYTCKASNAV 297
Score = 36.6 bits (83), Expect = 0.023
Identities = 31/131 (23%), Positives = 59/131 (45%), Gaps = 14/131 (10%)
Query: 93 SENDNGISFTCRLGRDQSVSV-SVVLNVTFPPLLSGNDFQTVEEG---------SNVKLV 142
++ ++ +TC + + +V + + V PP +S +D E G S + L
Sbjct: 1320 AQKEDAGQYTCVVTNELGEAVKNYHVEVLIPPSISKDD-PLAEVGVKEVKTKVNSTLTLE 1378
Query: 143 CNVKANPQAQMMWYKNSSLLDLEKSRHQIQQTSESFQLSITKVEKPDNGTYSCIAKSSLK 202
C A P + WYK+ + SR Q+ Q+ T+V D+G Y C+A +
Sbjct: 1379 CESWAVPPPTIRWYKDGQPVT-PSSRLQVLGEGRLLQIQPTQVS--DSGRYLCVATNVAG 1435
Query: 203 TESLDFHLIVK 213
+ DF+++++
Sbjct: 1436 EDDQDFNVLIQ 1446
Score = 36.2 bits (82), Expect = 0.030
Identities = 33/139 (23%), Positives = 61/139 (43%), Gaps = 24/139 (17%)
Query: 76 LKSGNKINSSS------------VCVSSISENDNGISFTC----RLGRDQSVSVSVVLNV 119
LK GN ++ + + ++S +D+G ++C +G D+ VVL V
Sbjct: 730 LKDGNPVSPAGTPGLQVFPGGRVLTLASARASDSG-RYSCVAVSAVGEDRQ---DVVLQV 785
Query: 120 TFPPLLSGNDFQ-TVEEGSNVKLVCNVKANPQAQMMWYKNSSLLDLEKSRHQIQQTSESF 178
PP + G + +V +V L C A P + W+K+ L+ R + +++
Sbjct: 786 HMPPSILGEELNVSVVANESVALECQSHAMPPPVLSWWKDGRPLE---PRPGVHLSADKA 842
Query: 179 QLSITKVEKPDNGTYSCIA 197
L + + + D G Y+C A
Sbjct: 843 LLQVDRADVWDAGHYTCEA 861
Score = 35.8 bits (81), Expect = 0.039
Identities = 44/174 (25%), Positives = 70/174 (40%), Gaps = 14/174 (8%)
Query: 33 VNGKTENYILDTTPGSQASLICAVQNHTREEELLWYREEGRV---DLKSGNKINSSSVCV 89
V + +++ PG Q L C+V+ + + W+R+ G V D + + +
Sbjct: 2301 VGPRGPRFVVGLAPG-QLVLECSVEAEPAPK-ITWHRD-GIVLQEDAHTQFPERGRFLQL 2357
Query: 90 SSISENDNGISFTCRLGRDQSVSVSVVLNV---TFPPLLSGNDFQTVEEGSNVKLVCNVK 146
++S D+G ++C R+ + S SV V T P + SG V L C
Sbjct: 2358 QALSTADSG-DYSCT-ARNAAGSTSVAFRVEIHTVPTIRSGPPAVNVSVNQTALLPCQAD 2415
Query: 147 ANPQAQMMWYKNSSLLDLEKSRHQIQQTSESFQLSITKVEKPDNGTYSCIAKSS 200
P + W K+ LD R +I L I V D G Y C+A +S
Sbjct: 2416 GVPAPLVSWRKDRVPLDPRSPRFEILPEG---SLRIQPVLAQDAGHYLCLASNS 2466
Score = 33.1 bits (74), Expect = 0.25
Identities = 19/84 (22%), Positives = 36/84 (42%), Gaps = 3/84 (3%)
Query: 129 DFQTVEEGSNVKLVCNVKANPQAQMMWYKNSSLLDLEKSRHQIQQTSESFQLSITKVEKP 188
+++ + E + L C+ A P + WY+ L + ++ L I V
Sbjct: 1476 EYREIVENNPAYLYCDTNAIPPPDLTWYREDQPL---SAGDEVSVLQGGRVLQIPLVRAE 1532
Query: 189 DNGTYSCIAKSSLKTESLDFHLIV 212
+ G YSC A + + + L + L+V
Sbjct: 1533 NAGRYSCKASNEVGEDWLHYELLV 1556
Score = 32.7 bits (73), Expect = 0.33
Identities = 33/134 (24%), Positives = 54/134 (40%), Gaps = 13/134 (9%)
Query: 112 SVSVVLNVTFPPLLSG-----NDFQTVEEGSNVKLVCNVKANPQAQMMWYKNSSLLDLEK 166
S + L V PP ++G V++G L CN P + W ++ + E
Sbjct: 963 SQDLQLEVHVPPQIAGPREPPTQVSVVQDGV-ATLECNATGKPPPTVTWERDGQPVGAEL 1021
Query: 167 SRHQIQQTSESFQLSITKVEKPDNGTYSCIAKSSLKTESLDFHL--IVKDKTVG--VPIE 222
Q+Q +S L + + + G YSC+A++ F L +V + +G P+
Sbjct: 1022 GL-QLQNQGQS--LHVERAQAAHTGRYSCVAENLAGRAERKFELSVLVPPELIGDLDPLT 1078
Query: 223 PIIAACVVIFLTLC 236
I AA LC
Sbjct: 1079 NITAALHSPLTLLC 1092
Score = 32.3 bits (72), Expect = 0.43
Identities = 31/126 (24%), Positives = 51/126 (40%), Gaps = 6/126 (4%)
Query: 89 VSSISENDNGISFTCRLGRDQSVSV-SVVLNVTFPPLLS-GNDFQTVEEGSNVKLVCNVK 146
+ + D GI +TC S V L V PP + G + V E ++V L C
Sbjct: 570 IEKVDLRDEGI-YTCAATNLAGESKREVALKVLVPPNIEPGPVNKAVLENASVTLECLAS 628
Query: 147 ANPQAQMMWYKNSSLLDLEKSRHQIQQTSESFQLSITKVEKPDNGTYSCIAKSSLKTESL 206
P + W+K + S + + + L I + + D G+Y C+A + + L
Sbjct: 629 GVPPPDVSWFKGHQPVS---SWMGVTVSVDGRVLRIEQAQLSDAGSYRCVASNVAGSTEL 685
Query: 207 DFHLIV 212
+ L V
Sbjct: 686 RYGLRV 691
Score = 31.6 bits (70), Expect = 0.73
Identities = 31/117 (26%), Positives = 48/117 (41%), Gaps = 4/117 (3%)
Query: 117 LNVTFPPL--LSGNDFQTVEEGSNVKLVCNVKANPQAQMMWYKNSSLLDLEKSRHQIQQT 174
LNV P+ L + TV EG +L C + P ++ W K+ L E + Q +
Sbjct: 874 LNVWVAPVFPLRESHTLTVREGHPTRLSCECRGVPFPKISWRKDGQPLPGEGAGLQ-HVS 932
Query: 175 SESFQLSITKVEKPDNGTYSCIAKSSLKTESLDFHLIVK-DKTVGVPIEPIIAACVV 230
+ L + + + GTY+C + + S D L V + P EP VV
Sbjct: 933 AVGRLLYLGQAQLAQEGTYTCECSNVVGNSSQDLQLEVHVPPQIAGPREPPTQVSVV 989
Score = 31.6 bits (70), Expect = 0.73
Identities = 34/169 (20%), Positives = 71/169 (42%), Gaps = 10/169 (5%)
Query: 65 LLWYREEGRVDLK---SGNKINSSSVCVSSISENDNGISFTCRLGRDQSVSVSVV-LNVT 120
++W+++ ++D + ++ S+ + + + F C + + + + + V
Sbjct: 2513 VVWWKDGQKLDFRLQQGAYRLLPSNALLLTAPGPQDSAQFECVVSNEVGEAHRLYQVTVH 2572
Query: 121 FPPLLSGN--DFQTVEEGSNVKLVCNVKANPQAQMMWYKNSSLLDLEKSRHQIQQTSESF 178
PP ++ + DF TV + V L C+ P + W K + L S +++ S S
Sbjct: 2573 VPPTIADDQTDF-TVTMMAPVVLTCHSTGIPAPTVSWSKAGAQLGARGSGYRV---SPSG 2628
Query: 179 QLSITKVEKPDNGTYSCIAKSSLKTESLDFHLIVKDKTVGVPIEPIIAA 227
L I + G Y+C A++S L V+ V P+ ++ A
Sbjct: 2629 ALEIGQALPIHAGRYTCSARNSAGVAHKHVFLTVQASPVVKPLPSVVRA 2677
Score = 31.2 bits (69), Expect = 0.96
Identities = 20/87 (22%), Positives = 40/87 (45%), Gaps = 7/87 (8%)
Query: 117 LNVTFPPLLSGN----DFQTVEEGSNVKLVCNVKANPQAQMMWYKNSSLLDLEKSRHQIQ 172
L+V PP L G+ T S + L+C P + W++ + + + +
Sbjct: 1062 LSVLVPPELIGDLDPLTNITAALHSPLTLLCEAMGIPPPAIRWFRGEEPVSPGEDTYLL- 1120
Query: 173 QTSESFQLSITKVEKPDNGTYSCIAKS 199
+ + L +T+ ++ D+G YSC+A +
Sbjct: 1121 --AGGWMLKMTQTQEQDSGLYSCLASN 1145
Score = 31.2 bits (69), Expect = 0.96
Identities = 20/86 (23%), Positives = 42/86 (48%), Gaps = 13/86 (15%)
Query: 117 LNVTFPPLLSGNDFQT---VEEGSNVKLVCNVKANPQAQMMWYKNSSLLDLEKSRHQIQQ 173
L V PP + + T + G+ ++L+C+ + PQ + W+K+ L +++
Sbjct: 2206 LTVMEPPHIEDSGQPTELSLTPGAPMELLCDAQGTPQPNITWHKDGQALT------RLEN 2259
Query: 174 TSESFQLSITKVEKPDNGTYSCIAKS 199
S + ++ + D G Y+C+A+S
Sbjct: 2260 NSRATRV----LRVRDAGLYTCLAES 2281
Score = 28.5 bits (62), Expect = 6.2
Identities = 21/75 (28%), Positives = 28/75 (37%), Gaps = 4/75 (5%)
Query: 139 VKLVCNVKANPQAQMMWYKNSSLLDLEKSRHQIQQTSESFQLSITKVEKPDNGTYSCIAK 198
V L C P+ + W K L + Q QL I D G Y CIAK
Sbjct: 2683 VLLPCEASGIPRPTITWQKEG----LNVATGVSTQVLPGGQLRIAHASPEDAGNYLCIAK 2738
Query: 199 SSLKTESLDFHLIVK 213
+S + L+V+
Sbjct: 2739 NSAGSAMGKTRLVVQ 2753
>gi|54792136 follistatin-like 4 [Homo sapiens]
Length = 842
Score = 55.5 bits (132), Expect = 5e-08
Identities = 43/179 (24%), Positives = 78/179 (43%), Gaps = 8/179 (4%)
Query: 41 ILDTTPGSQASLICAVQNHTREEELLWYREEGRVDLKSGNKINS----SSVCVSSISEND 96
+ T G L CAV R ++W R ++ IN S+ ++ ++
Sbjct: 257 VTTVTVGLSTVLTCAVHGDLRPP-IIWKRNGLTLNFLDLEDINDFGEDDSLYITKVTTIH 315
Query: 97 NGISFTCRLGRDQSVSVSVVLNVTFPPLLSGN-DFQTVEEGSNVKLVCNVKANPQAQMMW 155
G ++TC + + + VL V PP++ + Q E G L C+ + P ++ W
Sbjct: 316 MG-NYTCHASGHEQLFQTHVLQVNVPPVIRVYPESQAQEPGVAASLRCHAEGIPMPRITW 374
Query: 156 YKNSSLLDLEKSRHQIQQTSESFQLSITKVEKPDNGTYSCIAKSSLKTESLDFHLIVKD 214
KN + + S+ Q+ + +L I+ V D G Y+CIAK+ + + L ++D
Sbjct: 375 LKNGVDVSTQMSK-QLSLLANGSELHISSVRYEDTGAYTCIAKNEVGVDEDISSLFIED 432
>gi|169178458 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 3874
Score = 55.1 bits (131), Expect = 6e-08
Identities = 37/118 (31%), Positives = 64/118 (54%), Gaps = 14/118 (11%)
Query: 90 SSISENDNGISFTC----RLGRDQSVSVSVVLNVTFPPLLSGNDFQTVEE--GSNVKLVC 143
+++S D+G ++ C R+GR Q+VS ++V P+L G F + E G +++L C
Sbjct: 2994 AAVSREDSG-TYVCWAENRVGRTQAVSF---VHVKEAPVLQGEAFSYLVEPVGGSIQLDC 3049
Query: 144 NVKANPQAQMMWYKNSSLLDLEKSRHQIQQTSESFQLSITKVEKPDNGTYSCIAKSSL 201
V+ +P + W K+ L RHQ+Q S L+I + E+ D G Y C+A++ +
Sbjct: 3050 VVRGDPVPDIHWIKDGLPLRGSHLRHQLQNGS----LTIHRTERDDAGRYQCLAENEM 3103
Score = 50.4 bits (119), Expect = 2e-06
Identities = 47/179 (26%), Positives = 76/179 (42%), Gaps = 15/179 (8%)
Query: 42 LDTTPGSQASLICAVQNHTREEELLWYREEGRVDLKSGNKINSS--SVCVSSISENDNGI 99
L + PG +++C V+ + + W ++ + L ++ S ++ +S + D GI
Sbjct: 2132 LVSRPGELVTMVCPVRG-SPPIHVSWLKDGLPLPLSQRTLLHGSGHTLRISKVQLADAGI 2190
Query: 100 SFTCRLGRDQSVSV-SVVLNVTFPPLLSGNDFQT---VEEGSNVKLVCNVKANPQAQMMW 155
FTC V+ + L V PP+L +FQ V GS V+L C + P + W
Sbjct: 2191 -FTCVAASPAGVADRNFTLQVQVPPVLEPVEFQNDVVVVRGSLVELPCEARGVPLPLVSW 2249
Query: 156 YKNSSLLDLEKSRHQIQQTSESFQLSITKVEKPDNGTYSCIAKSSLKTESLDFHLIVKD 214
K+ L Q + L + V D+GTYSC+A S F L V +
Sbjct: 2250 MKDGEPL-------LSQSLEQGPSLQLEAVGAGDSGTYSCVAVSEAGEARRHFQLTVME 2301
Score = 46.6 bits (109), Expect = 2e-05
Identities = 34/120 (28%), Positives = 57/120 (47%), Gaps = 8/120 (6%)
Query: 82 INSSSVCVSSISENDNGISFTCRLGRDQSVSVSVV--LNVTFPPLLSGNDFQTVEE--GS 137
+ V S +E + S+ C + +Q+ S + L V PP ++G D + V S
Sbjct: 1704 LEDGQVLQVSTAEVADAASYMC-VAENQAGSAEKLFTLRVQVPPRIAGLDLEQVTAILNS 1762
Query: 138 NVKLVCNVKANPQAQMMWYKNSSLLDLEKSRHQIQQTSESFQLSITKVEKPDNGTYSCIA 197
+V L C+V A+P ++ WYK+S L L + + T L + + D+G Y+C A
Sbjct: 1763 SVSLPCDVHAHPNPEVTWYKDSQALSLGEEVFLLPGT---HTLQLGRARLSDSGMYTCEA 1819
Score = 46.2 bits (108), Expect = 3e-05
Identities = 47/176 (26%), Positives = 76/176 (43%), Gaps = 27/176 (15%)
Query: 48 SQASLICAVQNHTREEELLWYREEGRVDLKSGNKI----NSSSVCVSSISENDNGISFTC 103
S SL C V H E + WY++ + L G ++ + ++ + +D+G+ +TC
Sbjct: 1762 SSVSLPCDVHAHPNPE-VTWYKDSQALSL--GEEVFLLPGTHTLQLGRARLSDSGM-YTC 1817
Query: 104 RL----GRDQSVSVSVVLNVTFPPLL-----SGNDFQTVEEGSNVKLVCNVKANPQAQMM 154
GRDQ + V L+V PP D V G L C A P+ +
Sbjct: 1818 EALNAAGRDQKL---VQLSVLVPPAFRQAPRGPQDAVLVRVGDKAVLSCETDALPEPTVT 1874
Query: 155 WYKNSSLLDLEKSRHQIQQTSESFQLSITKVEKPDNGTYSC----IAKSSLKTESL 206
WYK+ L L + + Q +L I + + D G YSC +A +++T +L
Sbjct: 1875 WYKDGQPLVLAQ---RTQALRGGQRLEIQEAQVSDKGLYSCKVSNVAGEAVRTFTL 1927
Score = 46.2 bits (108), Expect = 3e-05
Identities = 40/173 (23%), Positives = 78/173 (45%), Gaps = 14/173 (8%)
Query: 42 LDTTPGSQASLICAVQNHTREEELLWYREEGRVDLKSGNKINSSSVCVSSISENDNGISF 101
L TPG+ L+C Q T + + W++ D ++ ++ ++S + D G+ +
Sbjct: 2314 LSLTPGAPMELLCDAQG-TPQPNITWHK-----DGQALTRLENNSRATRVLRVRDAGL-Y 2366
Query: 102 TCRLGRDQ-SVSVSVVLNVTFPPLLSGNDFQTVEEG---SNVKLVCNVKANPQAQMMWYK 157
TC ++ S + V PP + G G + L C+V+A P ++ W++
Sbjct: 2367 TCLAESPAGAIEKSFRVRVQAPPNIVGPRGPRFVVGLAPGQLVLECSVEAEPAPKITWHR 2426
Query: 158 NSSLLDLEKSRHQIQQTSESFQLSITKVEKPDNGTYSCIAKSSLKTESLDFHL 210
+ +L E + Q + QL + D+G YSC A+++ + S+ F +
Sbjct: 2427 DGIVLQ-EDAHTQFPERGRFLQLQA--LSTADSGDYSCTARNAAGSTSVAFRV 2476
Score = 45.8 bits (107), Expect = 4e-05
Identities = 41/183 (22%), Positives = 78/183 (42%), Gaps = 18/183 (9%)
Query: 41 ILDTTPGSQASLICAVQNHTREEELLWYREEGRVDLKSGNKINSSSVCVSSISENDNGIS 100
++ G A L+C V H + +L W+++ + + I+ V + + N +
Sbjct: 1263 VIKVLDGQTAHLMCNVTGHP-QPKLTWFKDGRPLARGDAHHISPDGVLLQVLQANLSSAG 1321
Query: 101 -FTCRLG-----RDQSVSVSVVLNVTFPPLLSGNDFQTVEE-----GSNVKLVCNVKANP 149
++C + + +SV+L P +L G + EE + + L+C A P
Sbjct: 1322 HYSCIAANAVGEKTKHFQLSVLLA---PTILGGAEDSADEEVTVTVNNPISLICEALAFP 1378
Query: 150 QAQMMWYKNSSLLDLEKSRHQIQQTSESFQLSITKVEKPDNGTYSCIAKSSLKTESLDFH 209
+ W K+ + E SR+ IQ + L I +K D G Y+C+ + L ++H
Sbjct: 1379 SPNITWMKDGA--PFEASRN-IQLLPGTHGLQILNAQKEDAGQYTCVVTNELGEAVKNYH 1435
Query: 210 LIV 212
+ V
Sbjct: 1436 VEV 1438
Score = 45.8 bits (107), Expect = 4e-05
Identities = 49/216 (22%), Positives = 90/216 (41%), Gaps = 22/216 (10%)
Query: 16 LLVILFLPREMTSSVLTVNGKTENYILDTTPGSQASLICAVQNHTREEELLWYREEGRVD 75
++ +L PR +S V E+++L+ G + L C ++ W ++ +
Sbjct: 2018 VVAVLVAPRIRSSGVAR-----EHHVLE---GQEVRLDCEADGQP-PPDVAWLKDGSPLG 2068
Query: 76 LKSGNKI----NSSSVCVSSISENDNGISFTCRLGRDQSVSVSV-VLNVTFPPLLS---- 126
G + + S+ + + +D G ++TC + +NV PP +
Sbjct: 2069 QDMGPHLRFYLDGGSLVLKGLRASDAG-AYTCVAHNPAGEDARLHTVNVLVPPTIKQGAD 2127
Query: 127 GNDFQTVEEGSNVKLVCNVKANPQAQMMWYKNSSLLDLEKSRHQIQQTSESFQLSITKVE 186
G+ G V +VC V+ +P + W K+ L L S+ + S L I+KV+
Sbjct: 2128 GSGTLVSRPGELVTMVCPVRGSPPIHVSWLKDG--LPLPLSQRTLLHGS-GHTLRISKVQ 2184
Query: 187 KPDNGTYSCIAKSSLKTESLDFHLIVKDKTVGVPIE 222
D G ++C+A S +F L V+ V P+E
Sbjct: 2185 LADAGIFTCVAASPAGVADRNFTLQVQVPPVLEPVE 2220
Score = 45.1 bits (105), Expect = 6e-05
Identities = 29/127 (22%), Positives = 54/127 (42%), Gaps = 6/127 (4%)
Query: 89 VSSISENDNGISFTCRLGRDQSVSVSVVLNVTFPPLLSGNDFQTVE---EGSNVKLVCNV 145
++ E D+G+ + + V PP + D + V +G L+CNV
Sbjct: 1219 MTQTQEQDSGLYSCLASNEAGEARRNFSVEVLVPPSIENEDLEEVIKVLDGQTAHLMCNV 1278
Query: 146 KANPQAQMMWYKNSSLLDLEKSRHQIQQTSESFQLSITKVEKPDNGTYSCIAKSSLKTES 205
+PQ ++ W+K+ L + H + + L + + G YSCIA +++ ++
Sbjct: 1279 TGHPQPKLTWFKDGRPLARGDAHH---ISPDGVLLQVLQANLSSAGHYSCIAANAVGEKT 1335
Query: 206 LDFHLIV 212
F L V
Sbjct: 1336 KHFQLSV 1342
Score = 44.3 bits (103), Expect = 1e-04
Identities = 42/174 (24%), Positives = 77/174 (44%), Gaps = 16/174 (9%)
Query: 64 ELLWYREEGRVDLKSGNKIN---SSSVCVSSISENDNGISFTCRLGRDQSVS-VSVVLNV 119
+L WYRE+ L +G++++ V + +N ++C+ + + L V
Sbjct: 1590 DLTWYREDQ--PLSAGDEVSVLQGGRVLQIPLVRAENAGRYSCKASNEVGEDWLHYELLV 1647
Query: 120 TFPPLLSGNDFQTVEE-----GSNVKLVCNVKANPQAQMMWYKNSSLLDLEKSRHQIQQT 174
PP++ G+ + VEE S V L C NP + W +N L R Q+ +
Sbjct: 1648 LTPPVILGDTEELVEEVTVNASSTVSLQCPALGNPVPTISWLQN-GLPFSPSPRLQVLED 1706
Query: 175 SESFQLSITKVEKPDNGTYSCIAKSSLKTESLDFHLIVK--DKTVGVPIEPIIA 226
+ Q+S +V D +Y C+A++ + F L V+ + G+ +E + A
Sbjct: 1707 GQVLQVSTAEV--ADAASYMCVAENQAGSAEKLFTLRVQVPPRIAGLDLEQVTA 1758
Score = 43.9 bits (102), Expect = 1e-04
Identities = 40/176 (22%), Positives = 78/176 (44%), Gaps = 20/176 (11%)
Query: 47 GSQASLICAVQNHTREEELLWYRE-------EGRVDLKSGNKINSSSVCVSSISENDNGI 99
G +A L C + E + WY++ + L+ G ++ VS D G+
Sbjct: 1856 GDKAVLSCET-DALPEPTVTWYKDGQPLVLAQRTQALRGGQRLEIQEAQVS-----DKGL 1909
Query: 100 SFTCRLGRDQSVSV-SVVLNVTFPPLLSGNDFQTVEE--GSNVKLVCNVKANPQAQMMWY 156
++C++ +V + L V PP +TV + GS + L C+V P + W
Sbjct: 1910 -YSCKVSNVAGEAVRTFTLTVQVPPTFENPKTETVSQVAGSPLVLTCDVSGVPAPTVTWL 1968
Query: 157 KNSSLLDLEKSRHQIQQTSESFQLSITKVEKPDNGTYSCIAKSSLKTESLDFHLIV 212
K+ ++ + H + S +L +++++ GTY+C+A+++ DF + V
Sbjct: 1969 KDRMPVE-SSAVHGV--VSRGGRLQLSRLQPAQAGTYTCVAENTQAEARKDFVVAV 2021
Score = 42.7 bits (99), Expect = 3e-04
Identities = 27/98 (27%), Positives = 47/98 (47%), Gaps = 6/98 (6%)
Query: 117 LNVTFPPLLSGN--DFQTVEEGSNVKLVCNVKANPQAQMMWYKNSSLLDLEKSRHQIQQT 174
L V PP++ D T E GS+ L C + +P+ + W K+ + + + IQ +
Sbjct: 2841 LVVQVPPVIENGLPDLSTTE-GSHAFLPCKARGSPEPNITWDKDGQPVSGAEGKFTIQPS 2899
Query: 175 SESFQLSITKVEKPDNGTYSCIAKSSLKTESLDFHLIV 212
E L + +E D GTY+C A++++ HL +
Sbjct: 2900 GE---LLVKNLEGQDAGTYTCTAENAVGRARRRVHLTI 2934
Score = 40.0 bits (92), Expect = 0.002
Identities = 44/195 (22%), Positives = 81/195 (41%), Gaps = 22/195 (11%)
Query: 33 VNGKTENYILDTTPGSQASLICAVQNHTREEELLWYREEGRVDLKSGN---KINSSSVCV 89
+ G+ +Y+++ GS L C V+ ++ W ++ + L+ + ++ + S+ +
Sbjct: 3029 LQGEAFSYLVEPVGGS-IQLDCVVRGDP-VPDIHWIKDG--LPLRGSHLRHQLQNGSLTI 3084
Query: 90 SSISENDNGISFTCRLGRDQSVSVSVVLNVTFPPLLSGNDFQ------TVEEGSNVKLVC 143
+D G + C + V+ VV+ V L S FQ TV G +V L C
Sbjct: 3085 HRTERDDAG-RYQCLAENEMGVAKKVVILV----LQSAPVFQVEPQDMTVRSGDDVALRC 3139
Query: 144 NVKANPQAQMMWYKNSSLLDLEKSRHQIQQTSESFQLSITKVEKPDNGTYSCIAKSSLKT 203
P + W + L + + S L + VE D GTY C+A + L +
Sbjct: 3140 QATGEPTPTIEWLQAGQPLRASRRLRTLPDGS----LWLENVETGDAGTYDCVAHNLLGS 3195
Query: 204 ESLDFHLIVKDKTVG 218
+ L+V+ + G
Sbjct: 3196 ATARAFLVVRGEPQG 3210
Score = 39.7 bits (91), Expect = 0.003
Identities = 28/100 (28%), Positives = 44/100 (44%), Gaps = 5/100 (5%)
Query: 113 VSVVLNVTFPPLLSGNDFQTVEEGSNVKLVCNVKANPQAQMMWYKNSSLLDLEKSRHQIQ 172
V+V +T PP L G V + V+L CN P +MW K+ + + +Q
Sbjct: 782 VNVPPRITLPPSLPG----PVLVNTPVRLTCNATGAPSPTLMWLKDGNPVS-PAGTPGLQ 836
Query: 173 QTSESFQLSITKVEKPDNGTYSCIAKSSLKTESLDFHLIV 212
L++ D+G YSC+A S++ + D L V
Sbjct: 837 VFPGGRVLTLASARASDSGRYSCVAVSAVGEDRQDVVLQV 876
Score = 37.7 bits (86), Expect = 0.010
Identities = 23/88 (26%), Positives = 43/88 (48%), Gaps = 6/88 (6%)
Query: 117 LNVTFPPLLSGNDFQ---TVEEGSNVKLVCNVKANPQAQMMWYKNSSLLDLEKSRHQIQQ 173
L V PP + G++ V E V+L+C + P + W+K+ +LL + ++
Sbjct: 304 LRVHAPPTIWGSNETGEVAVMEDHLVQLLCEARGVPTPNITWFKDGALL---PTSTKVVY 360
Query: 174 TSESFQLSITKVEKPDNGTYSCIAKSSL 201
T QL + + + D G Y+C A +++
Sbjct: 361 TRGGRQLQLGRAQSSDAGVYTCKASNAV 388
Score = 36.6 bits (83), Expect = 0.023
Identities = 35/154 (22%), Positives = 66/154 (42%), Gaps = 24/154 (15%)
Query: 76 LKSGNKINSSS------------VCVSSISENDNGISFTC----RLGRDQSVSVSVVLNV 119
LK GN ++ + + ++S +D+G ++C +G D+ VVL V
Sbjct: 821 LKDGNPVSPAGTPGLQVFPGGRVLTLASARASDSG-RYSCVAVSAVGEDRQ---DVVLQV 876
Query: 120 TFPPLLSGNDFQ-TVEEGSNVKLVCNVKANPQAQMMWYKNSSLLDLEKSRHQIQQTSESF 178
PP + G + +V +V L C A P + W+K+ L+ R + +++
Sbjct: 877 HMPPSILGEELNVSVVANESVALECQSHAMPPPVLSWWKDGRPLE---PRPGVHLSADKA 933
Query: 179 QLSITKVEKPDNGTYSCIAKSSLKTESLDFHLIV 212
L + + + D G Y+C A + ++L V
Sbjct: 934 LLQVDRADVWDAGHYTCEALNQAGRSEKHYNLNV 967
Score = 36.2 bits (82), Expect = 0.030
Identities = 29/130 (22%), Positives = 58/130 (44%), Gaps = 12/130 (9%)
Query: 93 SENDNGISFTCRLGRDQSVSV-SVVLNVTFPPLLSGND--------FQTVEEGSNVKLVC 143
++ ++ +TC + + +V + + V PP +S +D + S + L C
Sbjct: 1411 AQKEDAGQYTCVVTNELGEAVKNYHVEVLIPPSISKDDPLGEVGVKEVKTKVNSTLTLEC 1470
Query: 144 NVKANPQAQMMWYKNSSLLDLEKSRHQIQQTSESFQLSITKVEKPDNGTYSCIAKSSLKT 203
A P + WYK+ + SR Q+ Q+ T+V D+G Y C+A +
Sbjct: 1471 ESWAVPPPTIRWYKDGQPVT-PSSRLQVLGEGRLLQIQPTQVS--DSGRYLCVATNVAGE 1527
Query: 204 ESLDFHLIVK 213
+ DF+++++
Sbjct: 1528 DDQDFNVLIQ 1537
Score = 35.8 bits (81), Expect = 0.039
Identities = 44/174 (25%), Positives = 70/174 (40%), Gaps = 14/174 (8%)
Query: 33 VNGKTENYILDTTPGSQASLICAVQNHTREEELLWYREEGRV---DLKSGNKINSSSVCV 89
V + +++ PG Q L C+V+ + + W+R+ G V D + + +
Sbjct: 2392 VGPRGPRFVVGLAPG-QLVLECSVEAEPAPK-ITWHRD-GIVLQEDAHTQFPERGRFLQL 2448
Query: 90 SSISENDNGISFTCRLGRDQSVSVSVVLNV---TFPPLLSGNDFQTVEEGSNVKLVCNVK 146
++S D+G ++C R+ + S SV V T P + SG V L C
Sbjct: 2449 QALSTADSG-DYSCT-ARNAAGSTSVAFRVEIHTVPTIRSGPPAVNVSVNQTALLPCQAD 2506
Query: 147 ANPQAQMMWYKNSSLLDLEKSRHQIQQTSESFQLSITKVEKPDNGTYSCIAKSS 200
P + W K+ LD R +I L I V D G Y C+A +S
Sbjct: 2507 GVPAPLVSWRKDRVPLDPRSPRFEILPEG---SLRIQPVLAQDAGHYLCLASNS 2557
Score = 33.9 bits (76), Expect = 0.15
Identities = 23/77 (29%), Positives = 35/77 (45%), Gaps = 2/77 (2%)
Query: 136 GSNVKLVCNVKANPQAQMMWYKNSSLLDLEKSRHQIQQTSESFQLSITKVEKPDNGTYSC 195
G++V+L C P Q+ W K+ + Q+Q+ + L IT D G Y C
Sbjct: 232 GADVELQCWTSGVPTPQVEWTKDRQPVLPGGPHLQVQEDGQV--LRITGSHVGDEGRYQC 289
Query: 196 IAKSSLKTESLDFHLIV 212
+A S ++ DF L V
Sbjct: 290 VAFSPAGQQARDFQLRV 306
Score = 33.1 bits (74), Expect = 0.25
Identities = 19/84 (22%), Positives = 36/84 (42%), Gaps = 3/84 (3%)
Query: 129 DFQTVEEGSNVKLVCNVKANPQAQMMWYKNSSLLDLEKSRHQIQQTSESFQLSITKVEKP 188
+++ + E + L C+ A P + WY+ L + ++ L I V
Sbjct: 1567 EYREIVENNPAYLYCDTNAIPPPDLTWYREDQPL---SAGDEVSVLQGGRVLQIPLVRAE 1623
Query: 189 DNGTYSCIAKSSLKTESLDFHLIV 212
+ G YSC A + + + L + L+V
Sbjct: 1624 NAGRYSCKASNEVGEDWLHYELLV 1647
Score = 32.7 bits (73), Expect = 0.33
Identities = 33/134 (24%), Positives = 54/134 (40%), Gaps = 13/134 (9%)
Query: 112 SVSVVLNVTFPPLLSG-----NDFQTVEEGSNVKLVCNVKANPQAQMMWYKNSSLLDLEK 166
S + L V PP ++G V++G L CN P + W ++ + E
Sbjct: 1054 SQDLQLEVHVPPQIAGPREPPTQVSVVQDGV-ATLECNATGKPPPTVTWERDGQPVGAEL 1112
Query: 167 SRHQIQQTSESFQLSITKVEKPDNGTYSCIAKSSLKTESLDFHL--IVKDKTVG--VPIE 222
Q+Q +S L + + + G YSC+A++ F L +V + +G P+
Sbjct: 1113 GL-QLQNQGQS--LHVERAQAAHTGRYSCVAENLAGRAERKFELSVLVPPELIGDLDPLT 1169
Query: 223 PIIAACVVIFLTLC 236
I AA LC
Sbjct: 1170 NITAALHSPLTLLC 1183
Score = 32.3 bits (72), Expect = 0.43
Identities = 31/126 (24%), Positives = 51/126 (40%), Gaps = 6/126 (4%)
Query: 89 VSSISENDNGISFTCRLGRDQSVSV-SVVLNVTFPPLLS-GNDFQTVEEGSNVKLVCNVK 146
+ + D GI +TC S V L V PP + G + V E ++V L C
Sbjct: 661 IEKVDLRDEGI-YTCAATNLAGESKREVALKVLVPPNIEPGPVNKAVLENASVTLECLAS 719
Query: 147 ANPQAQMMWYKNSSLLDLEKSRHQIQQTSESFQLSITKVEKPDNGTYSCIAKSSLKTESL 206
P + W+K + S + + + L I + + D G+Y C+A + + L
Sbjct: 720 GVPPPDVSWFKGHQPVS---SWMGVTVSVDGRVLRIEQAQLSDAGSYRCVASNVAGSTEL 776
Query: 207 DFHLIV 212
+ L V
Sbjct: 777 RYGLRV 782
Score = 31.6 bits (70), Expect = 0.73
Identities = 34/169 (20%), Positives = 71/169 (42%), Gaps = 10/169 (5%)
Query: 65 LLWYREEGRVDLK---SGNKINSSSVCVSSISENDNGISFTCRLGRDQSVSVSVV-LNVT 120
++W+++ ++D + ++ S+ + + + F C + + + + + V
Sbjct: 2604 VVWWKDGQKLDFRLQQGAYRLLPSNALLLTAPGPQDSAQFECVVSNEVGEAHRLYQVTVH 2663
Query: 121 FPPLLSGN--DFQTVEEGSNVKLVCNVKANPQAQMMWYKNSSLLDLEKSRHQIQQTSESF 178
PP ++ + DF TV + V L C+ P + W K + L S +++ S S
Sbjct: 2664 VPPTIADDQTDF-TVTMMAPVVLTCHSTGIPAPTVSWSKAGAQLGARGSGYRV---SPSG 2719
Query: 179 QLSITKVEKPDNGTYSCIAKSSLKTESLDFHLIVKDKTVGVPIEPIIAA 227
L I + G Y+C A++S L V+ V P+ ++ A
Sbjct: 2720 ALEIGQALPIHAGRYTCSARNSAGVAHKHVFLTVQASPVVKPLPSVVRA 2768
Score = 31.2 bits (69), Expect = 0.96
Identities = 20/87 (22%), Positives = 40/87 (45%), Gaps = 7/87 (8%)
Query: 117 LNVTFPPLLSGN----DFQTVEEGSNVKLVCNVKANPQAQMMWYKNSSLLDLEKSRHQIQ 172
L+V PP L G+ T S + L+C P + W++ + + + +
Sbjct: 1153 LSVLVPPELIGDLDPLTNITAALHSPLTLLCEAMGIPPPAIRWFRGEEPVSPGEDTYLL- 1211
Query: 173 QTSESFQLSITKVEKPDNGTYSCIAKS 199
+ + L +T+ ++ D+G YSC+A +
Sbjct: 1212 --AGGWMLKMTQTQEQDSGLYSCLASN 1236
Score = 31.2 bits (69), Expect = 0.96
Identities = 20/86 (23%), Positives = 42/86 (48%), Gaps = 13/86 (15%)
Query: 117 LNVTFPPLLSGNDFQT---VEEGSNVKLVCNVKANPQAQMMWYKNSSLLDLEKSRHQIQQ 173
L V PP + + T + G+ ++L+C+ + PQ + W+K+ L +++
Sbjct: 2297 LTVMEPPHIEDSGQPTELSLTPGAPMELLCDAQGTPQPNITWHKDGQALT------RLEN 2350
Query: 174 TSESFQLSITKVEKPDNGTYSCIAKS 199
S + ++ + D G Y+C+A+S
Sbjct: 2351 NSRATRV----LRVRDAGLYTCLAES 2372
Score = 30.8 bits (68), Expect = 1.3
Identities = 31/117 (26%), Positives = 47/117 (40%), Gaps = 4/117 (3%)
Query: 117 LNVTFPPL--LSGNDFQTVEEGSNVKLVCNVKANPQAQMMWYKNSSLLDLEKSRHQIQQT 174
LNV P+ L + TV EG L C + P ++ W K+ L E + Q +
Sbjct: 965 LNVWVAPVFPLRESHTLTVREGHPTSLSCECRGVPFPKISWRKDGQPLPGEGAGLQ-HVS 1023
Query: 175 SESFQLSITKVEKPDNGTYSCIAKSSLKTESLDFHLIVK-DKTVGVPIEPIIAACVV 230
+ L + + + GTY+C + + S D L V + P EP VV
Sbjct: 1024 AVGRLLYLGQAQLAQEGTYTCECSNVVGNSSQDLQLEVHVPPQIAGPREPPTQVSVV 1080
Score = 28.5 bits (62), Expect = 6.2
Identities = 21/75 (28%), Positives = 28/75 (37%), Gaps = 4/75 (5%)
Query: 139 VKLVCNVKANPQAQMMWYKNSSLLDLEKSRHQIQQTSESFQLSITKVEKPDNGTYSCIAK 198
V L C P+ + W K L + Q QL I D G Y CIAK
Sbjct: 2774 VLLPCEASGIPRPTITWQKEG----LNVATGVSTQVLPGGQLRIAHASPEDAGNYLCIAK 2829
Query: 199 SSLKTESLDFHLIVK 213
+S + L+V+
Sbjct: 2830 NSAGSAMGKTRLVVQ 2844
>gi|239749684 PREDICTED: hemicentin 2 [Homo sapiens]
Length = 5065
Score = 55.1 bits (131), Expect = 6e-08
Identities = 37/118 (31%), Positives = 64/118 (54%), Gaps = 14/118 (11%)
Query: 90 SSISENDNGISFTC----RLGRDQSVSVSVVLNVTFPPLLSGNDFQTVEE--GSNVKLVC 143
+++S D+G ++ C R+GR Q+VS ++V P+L G F + E G +++L C
Sbjct: 4185 AAVSREDSG-TYVCWAENRVGRTQAVSF---VHVKEAPVLQGEAFSYLVEPVGGSIQLDC 4240
Query: 144 NVKANPQAQMMWYKNSSLLDLEKSRHQIQQTSESFQLSITKVEKPDNGTYSCIAKSSL 201
V+ +P + W K+ L RHQ+Q S L+I + E+ D G Y C+A++ +
Sbjct: 4241 VVRGDPVPDIHWIKDGLPLRGSHLRHQLQNGS----LTIHRTERDDAGRYQCLAENEM 4294
Score = 50.4 bits (119), Expect = 2e-06
Identities = 47/179 (26%), Positives = 76/179 (42%), Gaps = 15/179 (8%)
Query: 42 LDTTPGSQASLICAVQNHTREEELLWYREEGRVDLKSGNKINSS--SVCVSSISENDNGI 99
L + PG +++C V+ + + W ++ + L ++ S ++ +S + D GI
Sbjct: 3323 LVSRPGELVTMVCPVRG-SPPIHVSWLKDGLPLPLSQRTLLHGSGHTLRISKVQLADAGI 3381
Query: 100 SFTCRLGRDQSVSV-SVVLNVTFPPLLSGNDFQT---VEEGSNVKLVCNVKANPQAQMMW 155
FTC V+ + L V PP+L +FQ V GS V+L C + P + W
Sbjct: 3382 -FTCVAASPAGVADRNFTLQVQVPPVLEPVEFQNDVVVVRGSLVELPCEARGVPLPLVSW 3440
Query: 156 YKNSSLLDLEKSRHQIQQTSESFQLSITKVEKPDNGTYSCIAKSSLKTESLDFHLIVKD 214
K+ L Q + L + V D+GTYSC+A S F L V +
Sbjct: 3441 MKDGEPL-------LSQSLEQGPSLQLEAVGAGDSGTYSCVAVSEAGEARRHFQLTVME 3492
Score = 47.0 bits (110), Expect = 2e-05
Identities = 43/193 (22%), Positives = 84/193 (43%), Gaps = 25/193 (12%)
Query: 41 ILDTTPGSQASLICAVQNHTREEELLWYREEGRVDLKSGNKI---NSSSVCVSSISENDN 97
+L+ G ASL C + T + ++ W + L + S+ ++S+S D+
Sbjct: 1215 LLERVAGENASLPCPARG-TPKPQVTWRKGPSSEPLHGQPGVAVLEEGSLFLASVSPADS 1273
Query: 98 GISFTCRLGRDQ-SVSVSVVLNVTFPPLLSGNDFQTVEEG---SNVKLVCNVKANPQAQM 153
G + C+ + S S L V PP + + + G ++ L C+ P ++
Sbjct: 1274 G-DYECQATNEVGSTSRRAKLVVYVPPSIREDGRKANVSGMAGQSLTLECDANGFPVPEI 1332
Query: 154 MWYKNSSLLDL--------------EKSRHQIQQTSESFQLSITKVEKPDNGTYSCIAKS 199
+W K++ L+ + + H++ +S L ++++ D+G YSC A++
Sbjct: 1333 VWLKDAQLVGVPLGWAGYGWDLGWGQVGGHRLLDEGQS--LHFPRIQEGDSGLYSCRAEN 1390
Query: 200 SLKTESLDFHLIV 212
T DFHL+V
Sbjct: 1391 QAGTAQRDFHLLV 1403
Score = 46.6 bits (109), Expect = 2e-05
Identities = 42/172 (24%), Positives = 75/172 (43%), Gaps = 17/172 (9%)
Query: 47 GSQASLICAVQNHTREEELLWYREEGRVDLKSGNKINSS-SVCVSSISENDNGISFTCR- 104
G + + C+ + + W RE + S +++ ++ + ++ D G +++C+
Sbjct: 622 GVEVKVSCSASGYPTPH-ISWSRESQALQEDSRIHVDAQGTLIIQGVAPEDAG-NYSCQA 679
Query: 105 ---LGRDQSVSVSVVLNVTFPPLLSG-NDFQTVEEGSNVKLVCNVKANPQAQMMWYKNSS 160
+G DQ +V L T PP +S N V G LVC P +++WY+
Sbjct: 680 TNEVGTDQE---TVTLYYTDPPSVSAVNAVVLVAVGEEAVLVCEASGVPPPRVIWYRGGL 736
Query: 161 LLDLEKSRHQIQQTSESFQLSITKVEKPDNGTYSCIAKSSLKTESLDFHLIV 212
+ L + S S +L I ++ D GTY+C A + L S + L V
Sbjct: 737 EMIL------APEGSSSGKLRIPAAQERDAGTYTCRAVNELGDASAEIQLAV 782
Score = 46.6 bits (109), Expect = 2e-05
Identities = 34/120 (28%), Positives = 57/120 (47%), Gaps = 8/120 (6%)
Query: 82 INSSSVCVSSISENDNGISFTCRLGRDQSVSVSVV--LNVTFPPLLSGNDFQTVEE--GS 137
+ V S +E + S+ C + +Q+ S + L V PP ++G D + V S
Sbjct: 2895 LEDGQVLQVSTAEVADAASYMC-VAENQAGSAEKLFTLRVQVPPRIAGLDLEQVTAILNS 2953
Query: 138 NVKLVCNVKANPQAQMMWYKNSSLLDLEKSRHQIQQTSESFQLSITKVEKPDNGTYSCIA 197
+V L C+V A+P ++ WYK+S L L + + T L + + D+G Y+C A
Sbjct: 2954 SVSLPCDVHAHPNPEVTWYKDSQALSLGEEVFLLPGT---HTLQLGRARLSDSGMYTCEA 3010
Score = 46.2 bits (108), Expect = 3e-05
Identities = 47/176 (26%), Positives = 76/176 (43%), Gaps = 27/176 (15%)
Query: 48 SQASLICAVQNHTREEELLWYREEGRVDLKSGNKI----NSSSVCVSSISENDNGISFTC 103
S SL C V H E + WY++ + L G ++ + ++ + +D+G+ +TC
Sbjct: 2953 SSVSLPCDVHAHPNPE-VTWYKDSQALSL--GEEVFLLPGTHTLQLGRARLSDSGM-YTC 3008
Query: 104 RL----GRDQSVSVSVVLNVTFPPLL-----SGNDFQTVEEGSNVKLVCNVKANPQAQMM 154
GRDQ + V L+V PP D V G L C A P+ +
Sbjct: 3009 EALNAAGRDQKL---VQLSVLVPPAFRQAPRGPQDAVLVRVGDKAVLSCETDALPEPTVT 3065
Query: 155 WYKNSSLLDLEKSRHQIQQTSESFQLSITKVEKPDNGTYSC----IAKSSLKTESL 206
WYK+ L L + + Q +L I + + D G YSC +A +++T +L
Sbjct: 3066 WYKDGQPLVLAQ---RTQALRGGQRLEIQEAQVSDKGLYSCKVSNVAGEAVRTFTL 3118
Score = 46.2 bits (108), Expect = 3e-05
Identities = 40/173 (23%), Positives = 78/173 (45%), Gaps = 14/173 (8%)
Query: 42 LDTTPGSQASLICAVQNHTREEELLWYREEGRVDLKSGNKINSSSVCVSSISENDNGISF 101
L TPG+ L+C Q T + + W++ D ++ ++ ++S + D G+ +
Sbjct: 3505 LSLTPGAPMELLCDAQG-TPQPNITWHK-----DGQALTRLENNSRATRVLRVRDAGL-Y 3557
Query: 102 TCRLGRDQ-SVSVSVVLNVTFPPLLSGNDFQTVEEG---SNVKLVCNVKANPQAQMMWYK 157
TC ++ S + V PP + G G + L C+V+A P ++ W++
Sbjct: 3558 TCLAESPAGAIEKSFRVRVQAPPNIVGPRGPRFVVGLAPGQLVLECSVEAEPAPKITWHR 3617
Query: 158 NSSLLDLEKSRHQIQQTSESFQLSITKVEKPDNGTYSCIAKSSLKTESLDFHL 210
+ +L E + Q + QL + D+G YSC A+++ + S+ F +
Sbjct: 3618 DGIVLQ-EDAHTQFPERGRFLQLQA--LSTADSGDYSCTARNAAGSTSVAFRV 3667
Score = 45.8 bits (107), Expect = 4e-05
Identities = 41/183 (22%), Positives = 78/183 (42%), Gaps = 18/183 (9%)
Query: 41 ILDTTPGSQASLICAVQNHTREEELLWYREEGRVDLKSGNKINSSSVCVSSISENDNGIS 100
++ G A L+C V H + +L W+++ + + I+ V + + N +
Sbjct: 2454 VIKVLDGQTAHLMCNVTGHP-QPKLTWFKDGRPLARGDAHHISPDGVLLQVLQANLSSAG 2512
Query: 101 -FTCRLG-----RDQSVSVSVVLNVTFPPLLSGNDFQTVEE-----GSNVKLVCNVKANP 149
++C + + +SV+L P +L G + EE + + L+C A P
Sbjct: 2513 HYSCIAANAVGEKTKHFQLSVLLA---PTILGGAEDSADEEVTVTVNNPISLICEALAFP 2569
Query: 150 QAQMMWYKNSSLLDLEKSRHQIQQTSESFQLSITKVEKPDNGTYSCIAKSSLKTESLDFH 209
+ W K+ + E SR+ IQ + L I +K D G Y+C+ + L ++H
Sbjct: 2570 SPNITWMKDGA--PFEASRN-IQLLPGTHGLQILNAQKEDAGQYTCVVTNELGEAVKNYH 2626
Query: 210 LIV 212
+ V
Sbjct: 2627 VEV 2629
Score = 45.8 bits (107), Expect = 4e-05
Identities = 49/216 (22%), Positives = 90/216 (41%), Gaps = 22/216 (10%)
Query: 16 LLVILFLPREMTSSVLTVNGKTENYILDTTPGSQASLICAVQNHTREEELLWYREEGRVD 75
++ +L PR +S V E+++L+ G + L C ++ W ++ +
Sbjct: 3209 VVAVLVAPRIRSSGVAR-----EHHVLE---GQEVRLDCEADGQP-PPDVAWLKDGSPLG 3259
Query: 76 LKSGNKI----NSSSVCVSSISENDNGISFTCRLGRDQSVSVSV-VLNVTFPPLLS---- 126
G + + S+ + + +D G ++TC + +NV PP +
Sbjct: 3260 QDMGPHLRFYLDGGSLVLKGLRASDAG-AYTCVAHNPAGEDARLHTVNVLVPPTIKQGAD 3318
Query: 127 GNDFQTVEEGSNVKLVCNVKANPQAQMMWYKNSSLLDLEKSRHQIQQTSESFQLSITKVE 186
G+ G V +VC V+ +P + W K+ L L S+ + S L I+KV+
Sbjct: 3319 GSGTLVSRPGELVTMVCPVRGSPPIHVSWLKDG--LPLPLSQRTLLHGS-GHTLRISKVQ 3375
Query: 187 KPDNGTYSCIAKSSLKTESLDFHLIVKDKTVGVPIE 222
D G ++C+A S +F L V+ V P+E
Sbjct: 3376 LADAGIFTCVAASPAGVADRNFTLQVQVPPVLEPVE 3411
Score = 45.1 bits (105), Expect = 6e-05
Identities = 29/127 (22%), Positives = 54/127 (42%), Gaps = 6/127 (4%)
Query: 89 VSSISENDNGISFTCRLGRDQSVSVSVVLNVTFPPLLSGNDFQTVE---EGSNVKLVCNV 145
++ E D+G+ + + V PP + D + V +G L+CNV
Sbjct: 2410 MTQTQEQDSGLYSCLASNEAGEARRNFSVEVLVPPSIENEDLEEVIKVLDGQTAHLMCNV 2469
Query: 146 KANPQAQMMWYKNSSLLDLEKSRHQIQQTSESFQLSITKVEKPDNGTYSCIAKSSLKTES 205
+PQ ++ W+K+ L + H + + L + + G YSCIA +++ ++
Sbjct: 2470 TGHPQPKLTWFKDGRPLARGDAHH---ISPDGVLLQVLQANLSSAGHYSCIAANAVGEKT 2526
Query: 206 LDFHLIV 212
F L V
Sbjct: 2527 KHFQLSV 2533
Score = 44.3 bits (103), Expect = 1e-04
Identities = 42/174 (24%), Positives = 77/174 (44%), Gaps = 16/174 (9%)
Query: 64 ELLWYREEGRVDLKSGNKIN---SSSVCVSSISENDNGISFTCRLGRDQSVS-VSVVLNV 119
+L WYRE+ L +G++++ V + +N ++C+ + + L V
Sbjct: 2781 DLTWYREDQ--PLSAGDEVSVLQGGRVLQIPLVRAENAGRYSCKASNEVGEDWLHYELLV 2838
Query: 120 TFPPLLSGNDFQTVEE-----GSNVKLVCNVKANPQAQMMWYKNSSLLDLEKSRHQIQQT 174
PP++ G+ + VEE S V L C NP + W +N L R Q+ +
Sbjct: 2839 LTPPVILGDTEELVEEVTVNASSTVSLQCPALGNPVPTISWLQN-GLPFSPSPRLQVLED 2897
Query: 175 SESFQLSITKVEKPDNGTYSCIAKSSLKTESLDFHLIVK--DKTVGVPIEPIIA 226
+ Q+S +V D +Y C+A++ + F L V+ + G+ +E + A
Sbjct: 2898 GQVLQVSTAEV--ADAASYMCVAENQAGSAEKLFTLRVQVPPRIAGLDLEQVTA 2949
Score = 43.9 bits (102), Expect = 1e-04
Identities = 40/176 (22%), Positives = 78/176 (44%), Gaps = 20/176 (11%)
Query: 47 GSQASLICAVQNHTREEELLWYRE-------EGRVDLKSGNKINSSSVCVSSISENDNGI 99
G +A L C + E + WY++ + L+ G ++ VS D G+
Sbjct: 3047 GDKAVLSCET-DALPEPTVTWYKDGQPLVLAQRTQALRGGQRLEIQEAQVS-----DKGL 3100
Query: 100 SFTCRLGRDQSVSV-SVVLNVTFPPLLSGNDFQTVEE--GSNVKLVCNVKANPQAQMMWY 156
++C++ +V + L V PP +TV + GS + L C+V P + W
Sbjct: 3101 -YSCKVSNVAGEAVRTFTLTVQVPPTFENPKTETVSQVAGSPLVLTCDVSGVPAPTVTWL 3159
Query: 157 KNSSLLDLEKSRHQIQQTSESFQLSITKVEKPDNGTYSCIAKSSLKTESLDFHLIV 212
K+ ++ + H + S +L +++++ GTY+C+A+++ DF + V
Sbjct: 3160 KDRMPVE-SSAVHGV--VSRGGRLQLSRLQPAQAGTYTCVAENTQAEARKDFVVAV 3212
Score = 42.7 bits (99), Expect = 3e-04
Identities = 27/98 (27%), Positives = 47/98 (47%), Gaps = 6/98 (6%)
Query: 117 LNVTFPPLLSGN--DFQTVEEGSNVKLVCNVKANPQAQMMWYKNSSLLDLEKSRHQIQQT 174
L V PP++ D T E GS+ L C + +P+ + W K+ + + + IQ +
Sbjct: 4032 LVVQVPPVIENGLPDLSTTE-GSHAFLPCKARGSPEPNITWDKDGQPVSGAEGKFTIQPS 4090
Query: 175 SESFQLSITKVEKPDNGTYSCIAKSSLKTESLDFHLIV 212
E L + +E D GTY+C A++++ HL +
Sbjct: 4091 GE---LLVKNLEGQDAGTYTCTAENAVGRARRRVHLTI 4125
Score = 40.0 bits (92), Expect = 0.002
Identities = 44/195 (22%), Positives = 81/195 (41%), Gaps = 22/195 (11%)
Query: 33 VNGKTENYILDTTPGSQASLICAVQNHTREEELLWYREEGRVDLKSGN---KINSSSVCV 89
+ G+ +Y+++ GS L C V+ ++ W ++ + L+ + ++ + S+ +
Sbjct: 4220 LQGEAFSYLVEPVGGS-IQLDCVVRGDP-VPDIHWIKDG--LPLRGSHLRHQLQNGSLTI 4275
Query: 90 SSISENDNGISFTCRLGRDQSVSVSVVLNVTFPPLLSGNDFQ------TVEEGSNVKLVC 143
+D G + C + V+ VV+ V L S FQ TV G +V L C
Sbjct: 4276 HRTERDDAG-RYQCLAENEMGVAKKVVILV----LQSAPVFQVEPQDMTVRSGDDVALRC 4330
Query: 144 NVKANPQAQMMWYKNSSLLDLEKSRHQIQQTSESFQLSITKVEKPDNGTYSCIAKSSLKT 203
P + W + L + + S L + VE D GTY C+A + L +
Sbjct: 4331 QATGEPTPTIEWLQAGQPLRASRRLRTLPDGS----LWLENVETGDAGTYDCVAHNLLGS 4386
Query: 204 ESLDFHLIVKDKTVG 218
+ L+V+ + G
Sbjct: 4387 ATARAFLVVRGEPQG 4401
Score = 39.7 bits (91), Expect = 0.003
Identities = 28/100 (28%), Positives = 44/100 (44%), Gaps = 5/100 (5%)
Query: 113 VSVVLNVTFPPLLSGNDFQTVEEGSNVKLVCNVKANPQAQMMWYKNSSLLDLEKSRHQIQ 172
V+V +T PP L G V + V+L CN P +MW K+ + + +Q
Sbjct: 1973 VNVPPRITLPPSLPG----PVLVNTPVRLTCNATGAPSPTLMWLKDGNPVS-PAGTPGLQ 2027
Query: 173 QTSESFQLSITKVEKPDNGTYSCIAKSSLKTESLDFHLIV 212
L++ D+G YSC+A S++ + D L V
Sbjct: 2028 VFPGGRVLTLASARASDSGRYSCVAVSAVGEDRQDVVLQV 2067
Score = 37.7 bits (86), Expect = 0.010
Identities = 42/179 (23%), Positives = 67/179 (37%), Gaps = 8/179 (4%)
Query: 39 NYILDTTPGSQASLICAVQNHTREEELLWYREEGRVDLKSGNKINSSSVCVSSISENDNG 98
N ++ G +A L+C ++WYR G + + +S + + + E D G
Sbjct: 704 NAVVLVAVGEEAVLVCEASG-VPPPRVIWYRG-GLEMILAPEGSSSGKLRIPAAQERDAG 761
Query: 99 ISFTCRLGRDQS-VSVSVVLNVTFPPLLSGNDFQ-TVEEGSNVKLVCNVKANPQAQMMWY 156
++TCR + S + L V P L+ TVE G + L C P + W
Sbjct: 762 -TYTCRAVNELGDASAEIQLAVGHAPQLTELPRDVTVELGRSALLACRATGRPPPTVTWR 820
Query: 157 KNSSL---LDLEKSRHQIQQTSESFQLSITKVEKPDNGTYSCIAKSSLKTESLDFHLIV 212
+ L L R + +S L V D Y C A++ + LIV
Sbjct: 821 RGDGQPLGLRLGAGRGSRSRQPDSGVLFFESVAPEDQAPYVCEARNVFGKVQAEARLIV 879
Score = 37.7 bits (86), Expect = 0.010
Identities = 35/125 (28%), Positives = 55/125 (44%), Gaps = 7/125 (5%)
Query: 92 ISENDNGISFTCRLGRDQSVSVSV--VLNVTFPPLLSGNDFQTVE--EGSNVKLVCNVKA 147
I E D+G+ ++CR + +L +T P +L Q V G++V+L C
Sbjct: 1376 IQEGDSGL-YSCRAENQAGTAQRDFHLLVLTPPSVLGAGAAQEVLGLAGADVELQCWTSG 1434
Query: 148 NPQAQMMWYKNSSLLDLEKSRHQIQQTSESFQLSITKVEKPDNGTYSCIAKSSLKTESLD 207
P Q+ W K+ + Q+Q+ + L IT D G Y C+A S ++ D
Sbjct: 1435 VPTPQVEWTKDRQPVLPGGPHLQVQEDGQV--LRITGSHVGDEGRYQCVAFSPAGQQARD 1492
Query: 208 FHLIV 212
F L V
Sbjct: 1493 FQLRV 1497
Score = 37.7 bits (86), Expect = 0.010
Identities = 23/88 (26%), Positives = 43/88 (48%), Gaps = 6/88 (6%)
Query: 117 LNVTFPPLLSGNDFQ---TVEEGSNVKLVCNVKANPQAQMMWYKNSSLLDLEKSRHQIQQ 173
L V PP + G++ V E V+L+C + P + W+K+ +LL + ++
Sbjct: 1495 LRVHAPPTIWGSNETGEVAVMEDHLVQLLCEARGVPTPNITWFKDGALL---PTSTKVVY 1551
Query: 174 TSESFQLSITKVEKPDNGTYSCIAKSSL 201
T QL + + + D G Y+C A +++
Sbjct: 1552 TRGGRQLQLGRAQSSDAGVYTCKASNAV 1579
Score = 36.2 bits (82), Expect = 0.030
Identities = 33/139 (23%), Positives = 61/139 (43%), Gaps = 24/139 (17%)
Query: 76 LKSGNKINSSS------------VCVSSISENDNGISFTC----RLGRDQSVSVSVVLNV 119
LK GN ++ + + ++S +D+G ++C +G D+ VVL V
Sbjct: 2012 LKDGNPVSPAGTPGLQVFPGGRVLTLASARASDSG-RYSCVAVSAVGEDRQ---DVVLQV 2067
Query: 120 TFPPLLSGNDFQ-TVEEGSNVKLVCNVKANPQAQMMWYKNSSLLDLEKSRHQIQQTSESF 178
PP + G + +V +V L C A P + W+K+ L+ R + +++
Sbjct: 2068 HMPPSILGEELNVSVVANESVALECQSHAMPPPVLSWWKDGRPLE---PRPGVHLSADKA 2124
Query: 179 QLSITKVEKPDNGTYSCIA 197
L + + + D G Y+C A
Sbjct: 2125 LLQVDRADVWDAGHYTCEA 2143
Score = 36.2 bits (82), Expect = 0.030
Identities = 29/130 (22%), Positives = 58/130 (44%), Gaps = 12/130 (9%)
Query: 93 SENDNGISFTCRLGRDQSVSV-SVVLNVTFPPLLSGND--------FQTVEEGSNVKLVC 143
++ ++ +TC + + +V + + V PP +S +D + S + L C
Sbjct: 2602 AQKEDAGQYTCVVTNELGEAVKNYHVEVLIPPSISKDDPLGEVGVKEVKTKVNSTLTLEC 2661
Query: 144 NVKANPQAQMMWYKNSSLLDLEKSRHQIQQTSESFQLSITKVEKPDNGTYSCIAKSSLKT 203
A P + WYK+ + SR Q+ Q+ T+V D+G Y C+A +
Sbjct: 2662 ESWAVPPPTIRWYKDGQPVT-PSSRLQVLGEGRLLQIQPTQVS--DSGRYLCVATNVAGE 2718
Query: 204 ESLDFHLIVK 213
+ DF+++++
Sbjct: 2719 DDQDFNVLIQ 2728
Score = 35.8 bits (81), Expect = 0.039
Identities = 44/174 (25%), Positives = 70/174 (40%), Gaps = 14/174 (8%)
Query: 33 VNGKTENYILDTTPGSQASLICAVQNHTREEELLWYREEGRV---DLKSGNKINSSSVCV 89
V + +++ PG Q L C+V+ + + W+R+ G V D + + +
Sbjct: 3583 VGPRGPRFVVGLAPG-QLVLECSVEAEPAPK-ITWHRD-GIVLQEDAHTQFPERGRFLQL 3639
Query: 90 SSISENDNGISFTCRLGRDQSVSVSVVLNV---TFPPLLSGNDFQTVEEGSNVKLVCNVK 146
++S D+G ++C R+ + S SV V T P + SG V L C
Sbjct: 3640 QALSTADSG-DYSCT-ARNAAGSTSVAFRVEIHTVPTIRSGPPAVNVSVNQTALLPCQAD 3697
Query: 147 ANPQAQMMWYKNSSLLDLEKSRHQIQQTSESFQLSITKVEKPDNGTYSCIAKSS 200
P + W K+ LD R +I L I V D G Y C+A +S
Sbjct: 3698 GVPAPLVSWRKDRVPLDPRSPRFEILPEG---SLRIQPVLAQDAGHYLCLASNS 3748
Score = 35.0 bits (79), Expect = 0.066
Identities = 30/109 (27%), Positives = 48/109 (44%), Gaps = 5/109 (4%)
Query: 106 GRDQSVSVSVVLNVTFPPLLSGNDFQTVEEGSNVKLVCNVKAN-PQAQMMWYKNSSLLDL 164
G+ Q+ + +V P + S V EG V L C V A P + W K+ L
Sbjct: 869 GKVQAEARLIVTGHAPPQIASSAPTVRVLEGQPVSLPCIVLAGRPLPERHWLKDGRPLP- 927
Query: 165 EKSRHQIQQTSESFQLSITKVEKPDNGTYSCIAKSSLKTESLDFHLIVK 213
SRH I+ L + + + G YSC+A ++ ++ D L+V+
Sbjct: 928 PGSRHSIRADGS---LHLDRALQEHAGRYSCVATNTAGSQHRDVELVVQ 973
Score = 34.3 bits (77), Expect = 0.11
Identities = 32/131 (24%), Positives = 51/131 (38%), Gaps = 12/131 (9%)
Query: 84 SSSVCVSSISENDNGISFTCRLGRDQ-SVSVSVVLNVTFPPLLS-GNDFQTVEEGSNVKL 141
S S+ ++ + D+G + C S S VL V PP + G V G + L
Sbjct: 1081 SGSLRLAQVQVGDSG-HYECTASNPAGSASHRYVLGVQVPPQVQPGPRVLKVLVGEALDL 1139
Query: 142 VCNVKANPQAQMMWYKNSSLLDLEKSRHQIQQTSESFQLSITKVEKPDNGTYSCIAKSSL 201
C + NP+ Q+ W K+ +L Q + + D G Y C A +S
Sbjct: 1140 NCVAEGNPEPQLSWSKDGVVL---------QGRGPQGSVHFAAIRTSDAGRYRCEASNSA 1190
Query: 202 KTESLDFHLIV 212
++ + L V
Sbjct: 1191 GVDAWEVELRV 1201
Score = 33.1 bits (74), Expect = 0.25
Identities = 19/84 (22%), Positives = 36/84 (42%), Gaps = 3/84 (3%)
Query: 129 DFQTVEEGSNVKLVCNVKANPQAQMMWYKNSSLLDLEKSRHQIQQTSESFQLSITKVEKP 188
+++ + E + L C+ A P + WY+ L + ++ L I V
Sbjct: 2758 EYREIVENNPAYLYCDTNAIPPPDLTWYREDQPL---SAGDEVSVLQGGRVLQIPLVRAE 2814
Query: 189 DNGTYSCIAKSSLKTESLDFHLIV 212
+ G YSC A + + + L + L+V
Sbjct: 2815 NAGRYSCKASNEVGEDWLHYELLV 2838
Score = 32.7 bits (73), Expect = 0.33
Identities = 33/134 (24%), Positives = 54/134 (40%), Gaps = 13/134 (9%)
Query: 112 SVSVVLNVTFPPLLSG-----NDFQTVEEGSNVKLVCNVKANPQAQMMWYKNSSLLDLEK 166
S + L V PP ++G V++G L CN P + W ++ + E
Sbjct: 2245 SQDLQLEVHVPPQIAGPREPPTQVSVVQDGV-ATLECNATGKPPPTVTWERDGQPVGAEL 2303
Query: 167 SRHQIQQTSESFQLSITKVEKPDNGTYSCIAKSSLKTESLDFHL--IVKDKTVG--VPIE 222
Q+Q +S L + + + G YSC+A++ F L +V + +G P+
Sbjct: 2304 GL-QLQNQGQS--LHVERAQAAHTGRYSCVAENLAGRAERKFELSVLVPPELIGDLDPLT 2360
Query: 223 PIIAACVVIFLTLC 236
I AA LC
Sbjct: 2361 NITAALHSPLTLLC 2374
Score = 32.3 bits (72), Expect = 0.43
Identities = 31/126 (24%), Positives = 51/126 (40%), Gaps = 6/126 (4%)
Query: 89 VSSISENDNGISFTCRLGRDQSVSV-SVVLNVTFPPLLS-GNDFQTVEEGSNVKLVCNVK 146
+ + D GI +TC S V L V PP + G + V E ++V L C
Sbjct: 1852 IEKVDLRDEGI-YTCAATNLAGESKREVALKVLVPPNIEPGPVNKAVLENASVTLECLAS 1910
Query: 147 ANPQAQMMWYKNSSLLDLEKSRHQIQQTSESFQLSITKVEKPDNGTYSCIAKSSLKTESL 206
P + W+K + S + + + L I + + D G+Y C+A + + L
Sbjct: 1911 GVPPPDVSWFKGHQPVS---SWMGVTVSVDGRVLRIEQAQLSDAGSYRCVASNVAGSTEL 1967
Query: 207 DFHLIV 212
+ L V
Sbjct: 1968 RYGLRV 1973
Score = 31.6 bits (70), Expect = 0.73
Identities = 22/93 (23%), Positives = 37/93 (39%), Gaps = 3/93 (3%)
Query: 122 PPLLSGNDFQTVEEGSNVKLVCNVKANPQAQMMWYKNSSLLDLEKSRHQIQQTSESFQLS 181
PP L TV G L C V + W ++ +L R + Q ++ L
Sbjct: 517 PPQLVPAPNVTVSPGETAVLSCRVLGEAPYNLTWVRDWRVLPASTGR--VAQLAD-LSLE 573
Query: 182 ITKVEKPDNGTYSCIAKSSLKTESLDFHLIVKD 214
I+ + D G Y C+A ++ L+V++
Sbjct: 574 ISGIIPTDGGRYQCVASNANGVTRASVWLLVRE 606
Score = 31.6 bits (70), Expect = 0.73
Identities = 34/169 (20%), Positives = 71/169 (42%), Gaps = 10/169 (5%)
Query: 65 LLWYREEGRVDLK---SGNKINSSSVCVSSISENDNGISFTCRLGRDQSVSVSVV-LNVT 120
++W+++ ++D + ++ S+ + + + F C + + + + + V
Sbjct: 3795 VVWWKDGQKLDFRLQQGAYRLLPSNALLLTAPGPQDSAQFECVVSNEVGEAHRLYQVTVH 3854
Query: 121 FPPLLSGN--DFQTVEEGSNVKLVCNVKANPQAQMMWYKNSSLLDLEKSRHQIQQTSESF 178
PP ++ + DF TV + V L C+ P + W K + L S +++ S S
Sbjct: 3855 VPPTIADDQTDF-TVTMMAPVVLTCHSTGIPAPTVSWSKAGAQLGARGSGYRV---SPSG 3910
Query: 179 QLSITKVEKPDNGTYSCIAKSSLKTESLDFHLIVKDKTVGVPIEPIIAA 227
L I + G Y+C A++S L V+ V P+ ++ A
Sbjct: 3911 ALEIGQALPIHAGRYTCSARNSAGVAHKHVFLTVQASPVVKPLPSVVRA 3959
Score = 31.2 bits (69), Expect = 0.96
Identities = 20/87 (22%), Positives = 40/87 (45%), Gaps = 7/87 (8%)
Query: 117 LNVTFPPLLSGN----DFQTVEEGSNVKLVCNVKANPQAQMMWYKNSSLLDLEKSRHQIQ 172
L+V PP L G+ T S + L+C P + W++ + + + +
Sbjct: 2344 LSVLVPPELIGDLDPLTNITAALHSPLTLLCEAMGIPPPAIRWFRGEEPVSPGEDTYLL- 2402
Query: 173 QTSESFQLSITKVEKPDNGTYSCIAKS 199
+ + L +T+ ++ D+G YSC+A +
Sbjct: 2403 --AGGWMLKMTQTQEQDSGLYSCLASN 2427
Score = 31.2 bits (69), Expect = 0.96
Identities = 20/86 (23%), Positives = 42/86 (48%), Gaps = 13/86 (15%)
Query: 117 LNVTFPPLLSGNDFQT---VEEGSNVKLVCNVKANPQAQMMWYKNSSLLDLEKSRHQIQQ 173
L V PP + + T + G+ ++L+C+ + PQ + W+K+ L +++
Sbjct: 3488 LTVMEPPHIEDSGQPTELSLTPGAPMELLCDAQGTPQPNITWHKDGQALT------RLEN 3541
Query: 174 TSESFQLSITKVEKPDNGTYSCIAKS 199
S + ++ + D G Y+C+A+S
Sbjct: 3542 NSRATRV----LRVRDAGLYTCLAES 3563
Score = 30.8 bits (68), Expect = 1.3
Identities = 31/117 (26%), Positives = 47/117 (40%), Gaps = 4/117 (3%)
Query: 117 LNVTFPPL--LSGNDFQTVEEGSNVKLVCNVKANPQAQMMWYKNSSLLDLEKSRHQIQQT 174
LNV P+ L + TV EG L C + P ++ W K+ L E + Q +
Sbjct: 2156 LNVWVAPVFPLRESHTLTVREGHPTSLSCECRGVPFPKISWRKDGQPLPGEGAGLQ-HVS 2214
Query: 175 SESFQLSITKVEKPDNGTYSCIAKSSLKTESLDFHLIVK-DKTVGVPIEPIIAACVV 230
+ L + + + GTY+C + + S D L V + P EP VV
Sbjct: 2215 AVGRLLYLGQAQLAQEGTYTCECSNVVGNSSQDLQLEVHVPPQIAGPREPPTQVSVV 2271
Score = 28.9 bits (63), Expect = 4.8
Identities = 43/200 (21%), Positives = 68/200 (34%), Gaps = 16/200 (8%)
Query: 16 LLVILFLPREMTSSVLTVNGKTENYILDTTPGSQASLICAVQNHTREEELLWYREEGRVD 75
L+V P ++ SS TV G SL C V E W ++ +
Sbjct: 877 LIVTGHAPPQIASSAPTVR---------VLEGQPVSLPCIVLAGRPLPERHWLKDGRPLP 927
Query: 76 LKSGNKINSSSVCVSSISENDNGISFTC---RLGRDQSVSVSVVLNVTFPPLLSGNDFQT 132
S + I + + ++ ++C Q V +V+ V P +
Sbjct: 928 PGSRHSIRADGSLHLDRALQEHAGRYSCVATNTAGSQHRDVELVVQVP-PRIHPTATHHI 986
Query: 133 VEEGSNVKLVCNVKANPQAQMMWYKNSSLLDLEKSRHQIQQTSESFQLSITKVEKPDNGT 192
EG L C P + W K ++ L SR S+ L I + D G
Sbjct: 987 TNEGVPASLPCVASGVPAPTITWTKETNALT---SRGPHYNVSKEGTLLIAQPSAQDAGA 1043
Query: 193 YSCIAKSSLKTESLDFHLIV 212
Y C A +++ S + L V
Sbjct: 1044 YVCTATNTVGFSSQEMRLSV 1063
Score = 28.5 bits (62), Expect = 6.2
Identities = 21/75 (28%), Positives = 28/75 (37%), Gaps = 4/75 (5%)
Query: 139 VKLVCNVKANPQAQMMWYKNSSLLDLEKSRHQIQQTSESFQLSITKVEKPDNGTYSCIAK 198
V L C P+ + W K L + Q QL I D G Y CIAK
Sbjct: 3965 VLLPCEASGIPRPTITWQKEG----LNVATGVSTQVLPGGQLRIAHASPEDAGNYLCIAK 4020
Query: 199 SSLKTESLDFHLIVK 213
+S + L+V+
Sbjct: 4021 NSAGSAMGKTRLVVQ 4035
>gi|94538343 sialic acid binding Ig-like lectin 8 [Homo sapiens]
Length = 499
Score = 55.1 bits (131), Expect = 6e-08
Identities = 50/196 (25%), Positives = 89/196 (45%), Gaps = 40/196 (20%)
Query: 85 SSVCVSSISENDNGISFTCRL---GRDQSVSVSVVLNVTFPP----------------LL 125
SSV + D+G S TC++ G + + +V L+V++PP L
Sbjct: 206 SSVLTLTPKPQDHGTSLTCQVTLPGTGVTTTSTVRLDVSYPPWNLTMTVFQGDATASTAL 265
Query: 126 SGNDFQTVEEGSNVKLVCNVKANPQAQMMWYKNSSLLDLEKSRHQIQQTSESFQLSITKV 185
+V EG +++LVC V +NP A++ W + S L L SR +S L + +V
Sbjct: 266 GNGSSLSVLEGQSLRLVCAVNSNPPARLSWTRGS--LTLCPSR-----SSNPGLLELPRV 318
Query: 186 EKPDNGTYSCIAKSSLKTESLDFHLIVKDKTVGV--PIEPIIAACV-------VIFLTLC 236
D G ++C A+++ ++ + L ++++ G P+ + A V + FL+ C
Sbjct: 319 HVRDEGEFTCRAQNAQGSQHISLSLSLQNEGTGTSRPVSQVTLAAVGGAGATALAFLSFC 378
Query: 237 FGLIARRKKIMKLCMK 252
I I++ C K
Sbjct: 379 IIFI-----IVRSCRK 389
>gi|118572606 hemicentin 1 [Homo sapiens]
Length = 5635
Score = 53.5 bits (127), Expect = 2e-07
Identities = 49/187 (26%), Positives = 80/187 (42%), Gaps = 13/187 (6%)
Query: 33 VNGKTENYILDTTPGSQASLICAVQNHTREEELLWYREEGRVDLKSGNKINSSSVCVSSI 92
+ K+EN L + SL C V +L W + E + L + I + I
Sbjct: 2967 IGPKSEN--LTVVVNNFISLTCEVSGFP-PPDLSWLKNEQPIKLNTNTLIVPGGRTLQII 3023
Query: 93 -SENDNGISFTC-RLGRDQSVSVSVVLNVTFPPLLSGNDFQT-----VEEGSNVKLVCNV 145
++ +G +TC + + L V PP + +D ++ V EG++V L C
Sbjct: 3024 RAKVSDGGEYTCIAINQAGESKKKFSLTVYVPPSIKDHDSESLSVVNVREGTSVSLECES 3083
Query: 146 KANPQAQMMWYKNSSLLDLEKSRHQIQQTSESFQLSITKVEKPDNGTYSCIAKSSLKTES 205
A P + WYKN + + +S H ++ ++ L I K E D G Y C A + +
Sbjct: 3084 NAVPPPVITWYKNGRM--ITESTH-VEILADGQMLHIKKAEVSDTGQYVCRAINVAGRDD 3140
Query: 206 LDFHLIV 212
+FHL V
Sbjct: 3141 KNFHLNV 3147
Score = 52.0 bits (123), Expect = 5e-07
Identities = 41/162 (25%), Positives = 72/162 (44%), Gaps = 10/162 (6%)
Query: 65 LLWYREEGRVDLKSGNKINSSSVCVSSISEN-DNGISFTCRLGRDQSVSVSVV-LNVTFP 122
+ W+++ V L + +I S + + ++ +TC + + L+V P
Sbjct: 2418 ITWFKDGWPVSLSNSVRILSGGRMLRLMQTTMEDAGQYTCVVRNAAGEERKIFGLSVLVP 2477
Query: 123 PLLSGNDFQT---VEEGSNVKLVCNVKANPQAQMMWYKNSSLLDLEKSRHQIQQTSESFQ 179
P + G + V+E +V L C V NP ++ W+K+ L +++ H I S
Sbjct: 2478 PHIVGENTLEDVKVKEKQSVTLTCEVTGNPVPEITWHKDGQPLQEDEAHHII---SGGRF 2534
Query: 180 LSITKVEKPDNGTYSCIAKSSL--KTESLDFHLIVKDKTVGV 219
L IT V+ P G Y+C+A S K+ S ++ V GV
Sbjct: 2535 LQITNVQVPHTGRYTCLASSPAGHKSRSFSLNVFVSPTIAGV 2576
Score = 51.6 bits (122), Expect = 7e-07
Identities = 42/180 (23%), Positives = 78/180 (43%), Gaps = 7/180 (3%)
Query: 47 GSQASLICAVQNHTREEELLWYREEGRVDLKSGNK--INSSSVCVSSISENDNGISFTCR 104
G + +L C V++ + W +E + S + S S+ ++ +D+G+
Sbjct: 1094 GEEVTLPCEVKS-LPPPIITWAKETQLISPFSPRHTFLPSGSMKITETRTSDSGMYLCVA 1152
Query: 105 LGRDQSVSVSVVLNVTFPPLLS-GNDFQTVEEGSNVKLVCNVKANPQAQMMWYKNSSLLD 163
+V+ +V LNV PP + G V+ G V + CN + P + W K S +
Sbjct: 1153 TNIAGNVTQAVKLNVHVPPKIQRGPKHLKVQVGQRVDIPCNAQGTPLPVITWSKGGSTML 1212
Query: 164 LEKSRHQIQQTSESFQLSITKVEKPDNGTYSCIAKSSLKTESLDFHLIVKDKTVGVPIEP 223
++ H ++ LSI + D G Y+C+A + T+ + L V++ +EP
Sbjct: 1213 VDGEHH---VSNPDGTLSIDQATPSDAGIYTCVATNIAGTDETEITLHVQEPPTVEDLEP 1269
Score = 51.2 bits (121), Expect = 9e-07
Identities = 45/165 (27%), Positives = 75/165 (45%), Gaps = 11/165 (6%)
Query: 45 TPGSQASLICAVQNHTREEELLWYREEGRVDLKSGNKINSS---SVCVSSISENDNGISF 101
TPG +A L C + + + L W R + V L +I + S+ + S+ ND G +
Sbjct: 532 TPGERAVLTCLIISAV-DYNLTWQRNDRDVRLAEPARIRTLANLSLELKSVKFNDAG-EY 589
Query: 102 TCRLGRDQ-SVSVSVVLNVTFPPLLSGNDF-QTVEEGSNVKLVCNVKANPQAQMMWYKNS 159
C + + S + SV L V PP ++ Q+ GS V ++C+ P+ ++ W N
Sbjct: 590 HCMVSSEGGSSAASVFLTVQEPPKVTVMPKNQSFTGGSEVSIMCSATGYPKPKIAWTVND 649
Query: 160 SLLDLEKSRHQIQQTSESFQLSITKVEKPDNGTYSCIAKSSLKTE 204
+ H+ + TS+ L I D G Y C+A +S T+
Sbjct: 650 MFI---VGSHRYRMTSDG-TLFIKNAAPKDAGIYGCLASNSAGTD 690
Score = 49.3 bits (116), Expect = 3e-06
Identities = 42/154 (27%), Positives = 68/154 (44%), Gaps = 8/154 (5%)
Query: 65 LLWYREEGRVDLKSGNKI--NSSSVCVSSISENDNGISFTCRLGRDQS-VSVSVVLNVTF 121
L W ++ + K G I N S + + D G +TC + +N+
Sbjct: 2135 LTWLKDGHPLLKKPGLSISENRSVLKIEDAQVQDTG-RYTCEATNVAGKTEKNYNVNIWV 2193
Query: 122 PPLLSGNDFQT---VEEGSNVKLVCNVKANPQAQMMWYKNSSLLDLEKSRHQIQQTSESF 178
PP + G+D T V EG+ + L+C P ++W K S + L S +++ S
Sbjct: 2194 PPNIGGSDELTQLTVIEGNLISLLCESSGIPPPNLIWKKKGSPV-LTDSMGRVRILSGGR 2252
Query: 179 QLSITKVEKPDNGTYSCIAKSSLKTESLDFHLIV 212
QL I+ EK D YSC+A + T +++L V
Sbjct: 2253 QLQISIAEKSDAALYSCVASNVAGTAKKEYNLQV 2286
Score = 47.0 bits (110), Expect = 2e-05
Identities = 44/180 (24%), Positives = 83/180 (46%), Gaps = 21/180 (11%)
Query: 47 GSQASLICAVQNHTREEELLWYREEGR------VDLKSGNKINSSSVCVSSISENDNGIS 100
GS +L C VQ + E + W R + + S +++ + ++ + ++ +D G +
Sbjct: 807 GSNVTLPCYVQGYP-EPTIKWRRLDNMPIFSRPFSVSSISQLRTGALFILNLWASDKG-T 864
Query: 101 FTC----RLGRDQSVSVSVVLNVTFPPLLSGNDFQTVEEGSNVKLVCNVKA-NPQAQMMW 155
+ C + G+ QS + V + P + V EG + L C + A NP + W
Sbjct: 865 YICEAENQFGKIQSETTVTVTGLVAPLIGISPSVANVIEGQQLTLPCTLLAGNPIPERRW 924
Query: 156 YKNSSLLDLEKSRHQIQQTSESFQLSITKVEKPDNGTYSCIAK----SSLKTESLDFHLI 211
KNS++L L+ ++ L I +V+ D G Y+C+A ++ KT S+ H++
Sbjct: 925 IKNSAML-LQNPYITVRSDGS---LHIERVQLQDGGEYTCVASNVAGTNNKTTSVVVHVL 980
Score = 46.6 bits (109), Expect = 2e-05
Identities = 49/212 (23%), Positives = 90/212 (42%), Gaps = 23/212 (10%)
Query: 20 LFLPREMTSSVLTVNGKTENYILDTTPGSQASLICAVQNHTREEELLWYREEGRVDLKSG 79
+F P M +S+ G E +L GS S+ C + + T + W R+ + L +
Sbjct: 3430 VFAPPNMDNSM----GTEEITVLK---GSSTSMAC-ITDGTPAPSMAWLRDGQPLGLDAH 3481
Query: 80 NKINSSSVCVSSI-SENDNGISFTCRLGRDQS-VSVSVVLNVTFPPLLSGNDFQ---TVE 134
+++ + + + +E ++ +TC + VS +L V PP ++G++ +V
Sbjct: 3482 LTVSTHGMVLQLLKAETEDSGKYTCIASNEAGEVSKHFILKVLEPPHINGSEEHEEISVI 3541
Query: 135 EGSNVKLVCNVKANPQAQMMWYKNSSLLDLEKSRHQIQQTSESFQLSITKVEKPDNGTYS 194
+ ++L C P +M W K+ L Q+Q L I+ + D G Y+
Sbjct: 3542 VNNPLELTCIASGIPAPKMTWMKDGRPLP---QTDQVQTLGGGEVLRISTAQVEDTGRYT 3598
Query: 195 CIAKSSLKTESLDFHLIVKDKTVGVPIEPIIA 226
C+A S + K+ V V + P IA
Sbjct: 3599 CLASSPAGDDD-------KEYLVRVHVPPNIA 3623
Score = 45.8 bits (107), Expect = 4e-05
Identities = 34/177 (19%), Positives = 73/177 (41%), Gaps = 15/177 (8%)
Query: 48 SQASLICAVQNHTREEELLWYREEGRVDLKSGNKINSSSVCVSSIS-ENDNGISFTCRLG 106
S SL+C ++ + W+++ ++ +I + ++ + DN ++C
Sbjct: 2591 SPTSLVCEAYSYP-PATITWFKDGTPLESNRNIRILPGGRTLQILNAQEDNAGRYSCVAT 2649
Query: 107 RDQSVSVS-VVLNVTFPPLLSGNDFQ---------TVEEGSNVKLVCNVKANPQAQMMWY 156
+ + + V PP+++ D ++ + + L C A P A + WY
Sbjct: 2650 NEAGEMIKHYEVKVYIPPIINKGDLWGPGLSPKEVKIKVNNTLTLECEAYAIPSASLSWY 2709
Query: 157 KNSSLLDLEKSRHQIQQTSESFQLSITKVEKPDNGTYSCIAKSSLKTESLDFHLIVK 213
K+ L KS + + L I + + D G Y+C+A + + LDF + ++
Sbjct: 2710 KDGQPL---KSDDHVNIAANGHTLQIKEAQISDTGRYTCVASNIAGEDELDFDVNIQ 2763
Score = 43.1 bits (100), Expect = 2e-04
Identities = 34/156 (21%), Positives = 68/156 (43%), Gaps = 10/156 (6%)
Query: 65 LLWYREEGRVDLKSGNKIN----SSSVCVSSISENDNGISFTCRLGRDQSVSVSVV-LNV 119
+ W + R++ ++ S + ++ +D+G ++TC + + L++
Sbjct: 3183 IAWLKNHKRIENSDSLEVRILSGGSKLQIARSQHSDSG-NYTCIASNMEGKAQKYYFLSI 3241
Query: 120 TFPPLLSGNDFQT---VEEGSNVKLVCNVKANPQAQMMWYKNSSLLDLEKSRHQIQQTSE 176
PP ++G + + V G NV+LVCN P + W K+ + +I+ ++
Sbjct: 3242 QVPPSVAGAEIPSDVSVLLGENVELVCNANGIPTPLIQWLKDGKPI-ASGETERIRVSAN 3300
Query: 177 SFQLSITKVEKPDNGTYSCIAKSSLKTESLDFHLIV 212
L+I D G Y+C+A + E F+L V
Sbjct: 3301 GSTLNIYGALTSDTGKYTCVATNPAGEEDRIFNLNV 3336
Score = 42.0 bits (97), Expect = 5e-04
Identities = 41/157 (26%), Positives = 74/157 (47%), Gaps = 15/157 (9%)
Query: 64 ELLWYREEGRVDLKSGNK--INSSSVCVSSISENDNGISFTCRLGRDQ-SVSVSVVLNVT 120
++ W+++ GR ++S + ++S S+ ++ + D G +TC S S S L V
Sbjct: 4109 DITWHKD-GRAIVESIRQRVLSSGSLQIAFVQPGDAG-HYTCMAANVAGSSSTSTKLTVH 4166
Query: 121 FPPLLSGND-FQTVEEGSNVKLVCNVKANPQAQMMWYKNSSLLDLEKSRHQIQQTSESF- 178
PP + + TV E S L C P + W K++ LL ++ T+E +
Sbjct: 4167 VPPRIRSTEGHYTVNENSQAILPCVADGIPTPAINWKKDNVLLANLLGKY----TAEPYG 4222
Query: 179 QLSITKVEKPDNGTYSCIAKSS----LKTESLDFHLI 211
+L + V D+G Y+C+A ++ T SL H++
Sbjct: 4223 ELILENVVLEDSGFYTCVANNAAGEDTHTVSLTVHVL 4259
Score = 41.6 bits (96), Expect = 7e-04
Identities = 34/167 (20%), Positives = 69/167 (41%), Gaps = 8/167 (4%)
Query: 51 SLICAVQNHTREEELLWYREEGRVDLKSG-NKINSSSVCVSSISENDNGISFTCRLGRDQ 109
+L C V+ T ++WY++ +V S +N+ + + ++ ++C+
Sbjct: 1379 NLFCEVEG-TPSPIIMWYKDNVQVTESSTIQTVNNGKILKLFRATPEDAGRYSCKAINIA 1437
Query: 110 SVSVSVV-LNVTFPPLLSGNDFQ---TVEEGSNVKLVCNVKANPQAQMMWYKNSSLLDLE 165
S ++V PP + G +F +V +V L C VK P + W+K+ L L
Sbjct: 1438 GTSQKYFNIDVLVPPTIIGTNFPNEVSVVLNRDVALECQVKGTPFPDIHWFKDGKPLFLG 1497
Query: 166 KSRHQIQQTSESFQLSITKVEKPDNGTYSCIAKSSLKTESLDFHLIV 212
++ + L + + D G Y C ++ ++ D L +
Sbjct: 1498 DPNVELLDRGQ--VLHLKNARRNDKGRYQCTVSNAAGKQAKDIKLTI 1542
Score = 41.6 bits (96), Expect = 7e-04
Identities = 28/99 (28%), Positives = 43/99 (43%), Gaps = 6/99 (6%)
Query: 117 LNVTFPPLLS---GNDFQTVEEGSNVKLVCNVKANPQAQMMWYKNSSLLDLEKSRHQIQQ 173
L V PP + G + TV +GS+ + C P M W ++ L L+ +
Sbjct: 3428 LQVFAPPNMDNSMGTEEITVLKGSSTSMACITDGTPAPSMAWLRDGQPLGLDA---HLTV 3484
Query: 174 TSESFQLSITKVEKPDNGTYSCIAKSSLKTESLDFHLIV 212
++ L + K E D+G Y+CIA + S F L V
Sbjct: 3485 STHGMVLQLLKAETEDSGKYTCIASNEAGEVSKHFILKV 3523
Score = 40.8 bits (94), Expect = 0.001
Identities = 37/162 (22%), Positives = 68/162 (41%), Gaps = 13/162 (8%)
Query: 65 LLWYREEGRVDLKSGNK----INSSSVC-VSSISENDNGISFTCRLGRDQSVSVSVVLNV 119
+ WY++ L SG+ +N + + S +D GI + + + L V
Sbjct: 1952 ITWYKDNR---LLSGSTSMTFLNRGQIIDIESAQISDAGIYKCVAINSAGATELFYSLQV 2008
Query: 120 TFPPLLSG-NDFQTVEEGSNVKLVCNVKANPQAQMMWYKNSSLLDLEKSRHQIQQTSESF 178
P +SG N+ V + V+L C + P + W K+ S + + +Q S
Sbjct: 2009 HVAPSISGSNNMVAVVVNNPVRLECEARGIPAPSLTWLKDGS--PVSSFSNGLQVLSGGR 2066
Query: 179 QLSITKVEKPDNGTYSCIAKSSL--KTESLDFHLIVKDKTVG 218
L++T + D G Y+C+A ++ K +D + V +G
Sbjct: 2067 ILALTSAQISDTGRYTCVAVNAAGEKQRDIDLRVYVPPNIMG 2108
Score = 40.0 bits (92), Expect = 0.002
Identities = 46/188 (24%), Positives = 77/188 (40%), Gaps = 19/188 (10%)
Query: 34 NGKTENYILDTTPGSQASLICAVQNHTREEELLWYREEGRVDLKSGNKINSSSVCVSSIS 93
+G +E ++ P +L C + N + W +++ V+ GN SS V I+
Sbjct: 1831 SGLSERVVVKYKP---VALQC-IANGIPNPSITWLKDDQPVNTAQGNLKIQSSGRVLQIA 1886
Query: 94 EN--DNGISFTC----RLGRDQSVSVSVVLNVTFPPLLSGNDF---QTVEEGSNVKLVCN 144
+ ++ +TC G Q + L+V PP L +TV + V+L C
Sbjct: 1887 KTLLEDAGRYTCVATNAAGETQQ---HIQLHVHEPPSLEDAGKMLNETVLVSNPVQLECK 1943
Query: 145 VKANPQAQMMWYKNSSLLDLEKSRHQIQQTSESFQLSITKVEKPDNGTYSCIAKSSLKTE 204
NP + WYK++ LL S + + + I + D G Y C+A +S
Sbjct: 1944 AAGNPVPVITWYKDNRLLSGSTSMTFLNRGQ---IIDIESAQISDAGIYKCVAINSAGAT 2000
Query: 205 SLDFHLIV 212
L + L V
Sbjct: 2001 ELFYSLQV 2008
Score = 39.7 bits (91), Expect = 0.003
Identities = 26/101 (25%), Positives = 42/101 (41%), Gaps = 6/101 (5%)
Query: 115 VVLNVTFPPLLSGNDFQT---VEEGSNVKLVCNVKANPQAQMMWYKNSSLLDLEKSRHQI 171
+ L + PP + G + T V S +KL C + P + WYK+ + S Q
Sbjct: 1538 IKLTIYIPPSIKGGNVTTDISVLINSLIKLECETRGLPMPAITWYKDGQPI---MSSSQA 1594
Query: 172 QQTSESFQLSITKVEKPDNGTYSCIAKSSLKTESLDFHLIV 212
+ L I + + D+ TY+C + T FH+ V
Sbjct: 1595 LYIDKGQYLHIPRAQVSDSATYTCHVANVAGTAEKSFHVDV 1635
Score = 39.7 bits (91), Expect = 0.003
Identities = 32/154 (20%), Positives = 60/154 (38%), Gaps = 16/154 (10%)
Query: 89 VSSISENDNGISFTCRLGRDQSVSVSVVLNVTFPPLLSGND---FQTVEEGSNVKLVCNV 145
+ S E D G + ++V PP + G D + V + ++L C+V
Sbjct: 1699 IMSAQEIDRGQYICVATSVAGEKEIKYEVDVLVPPAIEGGDETSYFIVMVNNLLELDCHV 1758
Query: 146 KANPQAQMMWYKNSSLLDLEKSRHQIQQTSESFQLSITKVEKPDNGTYSCIAKSSLKTES 205
+P +MW K+ L+D R + +L I + + + G Y C+A ++
Sbjct: 1759 TGSPPPTIMWLKDGQLID---ERDGFKILLNGRKLVIAQAQVSNTGLYRCMAANTAGDHK 1815
Query: 206 LDFHLIVK----------DKTVGVPIEPIIAACV 229
+F + V + V V +P+ C+
Sbjct: 1816 KEFEVTVHVPPTIKSSGLSERVVVKYKPVALQCI 1849
Score = 39.7 bits (91), Expect = 0.003
Identities = 36/145 (24%), Positives = 64/145 (44%), Gaps = 13/145 (8%)
Query: 85 SSVCVSSISENDNGISFTCRLGRDQSVSVSVVLNVTF---PPLLSGNDFQTVEE--GSNV 139
S + + +S+ D+G ++ C + SV + + PP+ G+ E G N
Sbjct: 4311 SELVIERVSKEDSG-TYVCTA--ENSVGFVKAIGFVYVKEPPVFKGDYPSNWIEPLGGNA 4367
Query: 140 KLVCNVKANPQAQMMWYKNSSLLDLEKSRHQIQQTSESFQLSITKVEKPDNGTYSCIAKS 199
L C VK +P + W N +D+E S H+I+Q L+I D G Y+C+A +
Sbjct: 4368 ILNCEVKGDPTPTIQW--NRKGVDIEIS-HRIRQLGNG-SLAIYGTVNEDAGDYTCVATN 4423
Query: 200 SLKTESLDFHLIVKDKTVGVPIEPI 224
L ++ + + +EP+
Sbjct: 4424 EAGVVERSMSLTLQSPPI-ITLEPV 4447
Score = 37.7 bits (86), Expect = 0.010
Identities = 33/164 (20%), Positives = 62/164 (37%), Gaps = 9/164 (5%)
Query: 41 ILDTTPGSQASLICAVQNHTREEELLWYREEGRVDLKSGNKINSS-SVCVSSISENDNGI 99
+ + G Q +L C + E W + + + S S+ + + D G
Sbjct: 898 VANVIEGQQLTLPCTLLAGNPIPERRWIKNSAMLLQNPYITVRSDGSLHIERVQLQDGG- 956
Query: 100 SFTC---RLGRDQSVSVSVVLNVTFPPLLSGNDFQTVEEGSNVKLVCNVKANPQAQMMWY 156
+TC + + + SVV++V P + G + EG V L C NP+ ++W
Sbjct: 957 EYTCVASNVAGTNNKTTSVVVHV-LPTIQHGQQILSTIEGIPVTLPCKASGNPKPSVIWS 1015
Query: 157 KNSSLLDLEKSRHQIQQTSESFQLSITKVEKPDNGTYSCIAKSS 200
K L+ ++ L + ++G Y C A ++
Sbjct: 1016 KKGELISTSSAKF---SAGADGSLYVVSPGGEESGEYVCTATNT 1056
Score = 37.4 bits (85), Expect = 0.013
Identities = 35/147 (23%), Positives = 58/147 (39%), Gaps = 11/147 (7%)
Query: 69 REEGRVDLKSGNKINSSSVCVSSISENDNGISFTCRLGRDQSVSVSVVLNVTFPPLLSGN 128
RE G L+ G + ++S++ DNG + + L V PP++
Sbjct: 1310 REPGISILEDGTLL-----VIASVTPYDNGEYICVAVNEAGTTERKYNLKVHVPPVIKDK 1364
Query: 129 DFQT---VEEGSNVKLVCNVKANPQAQMMWYKNSSLLDLEKSRHQIQQTSESFQLSITKV 185
+ T V L C V+ P +MWYK++ + + IQ + L + +
Sbjct: 1365 EQVTNVSVLLNQLTNLFCEVEGTPSPIIMWYKDNVQVTESST---IQTVNNGKILKLFRA 1421
Query: 186 EKPDNGTYSCIAKSSLKTESLDFHLIV 212
D G YSC A + T F++ V
Sbjct: 1422 TPEDAGRYSCKAINIAGTSQKYFNIDV 1448
Score = 37.4 bits (85), Expect = 0.013
Identities = 34/120 (28%), Positives = 51/120 (42%), Gaps = 16/120 (13%)
Query: 112 SVSVVLNVTFPPLLSG------NDFQTVEEGSNVKLVCNVKANPQAQMMWYKNSSLLDLE 165
S S LNV P ++G + TV S LVC + P A + W+K+ + L+
Sbjct: 2560 SRSFSLNVFVSPTIAGVGSDGNPEDVTVILNSPTSLVCEAYSYPPATITWFKDGTPLE-- 2617
Query: 166 KSRHQIQQTSESFQLSITKVEKPDNGTYSCIAKSSLKTESLDFHLIVKDKTVGVPIEPII 225
S I+ L I ++ + G YSC+A + ++K V V I PII
Sbjct: 2618 -SNRNIRILPGGRTLQILNAQEDNAGRYSCVATNEAGE-------MIKHYEVKVYIPPII 2669
Score = 37.0 bits (84), Expect = 0.017
Identities = 26/100 (26%), Positives = 44/100 (44%), Gaps = 7/100 (7%)
Query: 117 LNVTFPPLLSGNDFQ----TVEEGSNVKLVCNVKANPQAQMMWYKNSSLLDLEKSRHQIQ 172
L+V PP + GN +V E ++V L C P + W+K+ + L S ++
Sbjct: 2378 LSVHAPPSIIGNHRSPENISVVEKNSVSLTCEASGIPLPSITWFKDGWPVSLSNS---VR 2434
Query: 173 QTSESFQLSITKVEKPDNGTYSCIAKSSLKTESLDFHLIV 212
S L + + D G Y+C+ +++ E F L V
Sbjct: 2435 ILSGGRMLRLMQTTMEDAGQYTCVVRNAAGEERKIFGLSV 2474
Score = 36.6 bits (83), Expect = 0.023
Identities = 21/66 (31%), Positives = 30/66 (45%), Gaps = 3/66 (4%)
Query: 132 TVEEGSNVKLVCNVKANPQAQMMWYKNSSLLDLEKSRHQIQQTSESFQLSITKVEKPDNG 191
+V G V L C VK+ P + W K + L+ RH S + IT+ D+G
Sbjct: 1090 SVLAGEEVTLPCEVKSLPPPIITWAKETQLISPFSPRHTF---LPSGSMKITETRTSDSG 1146
Query: 192 TYSCIA 197
Y C+A
Sbjct: 1147 MYLCVA 1152
Score = 36.2 bits (82), Expect = 0.030
Identities = 29/111 (26%), Positives = 53/111 (47%), Gaps = 14/111 (12%)
Query: 96 DNGISFTC----RLGRD-QSVSVSVVLNVTFPPLLSGNDFQTVEEGSNVKLVCNVKANPQ 150
D+G +TC G D +VS++V + TF L ++ +G ++L C P
Sbjct: 4233 DSGF-YTCVANNAAGEDTHTVSLTVHVLPTFTELPGD---VSLNKGEQLRLSCKATGIPL 4288
Query: 151 AQMMWYKNSSLLDLEKSRHQIQQTSESFQLSITKVEKPDNGTYSCIAKSSL 201
++ W N++++ + +L I +V K D+GTY C A++S+
Sbjct: 4289 PKLTWTFNNNIIPAH-----FDSVNGHSELVIERVSKEDSGTYVCTAENSV 4334
Score = 34.7 bits (78), Expect = 0.087
Identities = 25/118 (21%), Positives = 51/118 (43%), Gaps = 8/118 (6%)
Query: 100 SFTCRLGRDQSVSV-SVVLNVTFPPLLSGNDFQTVEE----GSNVKLVCNVKANPQAQMM 154
++TC + + S ++V PP++ GN + + ++ L C NP +
Sbjct: 1615 TYTCHVANVAGTAEKSFHVDVYVPPMIEGNLATPLNKQVVIAHSLTLECKAAGNPSPILT 1674
Query: 155 WYKNSSLLDLEKSRHQIQQTSESFQLSITKVEKPDNGTYSCIAKSSLKTESLDFHLIV 212
W K+ + K+ I+ + +L I ++ D G Y C+A S + + + + V
Sbjct: 1675 WLKDGVPV---KANDNIRIEAGGKKLEIMSAQEIDRGQYICVATSVAGEKEIKYEVDV 1729
Score = 34.7 bits (78), Expect = 0.087
Identities = 41/169 (24%), Positives = 67/169 (39%), Gaps = 30/169 (17%)
Query: 65 LLWYREEGRVDLKSGNKINSSS----VCVSSISENDNGISFTCRL----GRDQSVSVSVV 116
L WY++ LKS + +N ++ + + +D G +TC G D+ +
Sbjct: 2706 LSWYKDGQ--PLKSDDHVNIAANGHTLQIKEAQISDTG-RYTCVASNIAGEDE---LDFD 2759
Query: 117 LNVTFPPLLS-----GNDFQTVEEG--------SNVKLVCNVKANPQAQMMWYKNSSLLD 163
+N+ PP GN T G + + L C A P + WYK+ L
Sbjct: 2760 VNIQVPPSFQKLWEIGNMLDTGRNGEAKDVIINNPISLYCETNAAPPPTLTWYKDGHPLT 2819
Query: 164 LEKSRHQIQQTSESFQLSITKVEKPDNGTYSCIAKSSLKTESLDFHLIV 212
+ I Q+ KVE D G Y+C+A + +SL + + V
Sbjct: 2820 -SSDKVLILPGGRVLQIPRAKVE--DAGRYTCVAVNEAGEDSLQYDVRV 2865
Score = 34.7 bits (78), Expect = 0.087
Identities = 44/192 (22%), Positives = 77/192 (40%), Gaps = 27/192 (14%)
Query: 34 NGKTENYILDTTPGSQASLICAVQNHTREEELLWYREEGRVDLKSGNKI----NSSSVCV 89
NG+ ++ I++ + SL C N L WY++ L S +K+ + +
Sbjct: 2783 NGEAKDVIIN----NPISLYCET-NAAPPPTLTWYKDGH--PLTSSDKVLILPGGRVLQI 2835
Query: 90 SSISENDNGISFTC----RLGRDQSVSVSVVLNVTFPPLLSGNDFQTVEE-----GSNVK 140
D G +TC G D S+ + V PP++ G + EE +
Sbjct: 2836 PRAKVEDAG-RYTCVAVNEAGED---SLQYDVRVLVPPIIKGANSDLPEEVTVLVNKSAL 2891
Query: 141 LVCNVKANPQAQMMWYKNSSLLDLEKSRHQIQQTSESFQLSITKVEKPDNGTYSCIAKSS 200
+ C +P + W K+ L LE H+ Q+ T++ D G Y C+A+++
Sbjct: 2892 IECLSSGSPAPRNSWQKDGQPL-LEDDHHKFLSNGRILQILNTQIT--DIGRYVCVAENT 2948
Query: 201 LKTESLDFHLIV 212
+ F+L V
Sbjct: 2949 AGSAKKYFNLNV 2960
Score = 34.7 bits (78), Expect = 0.087
Identities = 34/151 (22%), Positives = 59/151 (39%), Gaps = 7/151 (4%)
Query: 65 LLWYREEGRVDLKSGNK--INSSSVCVSSISENDNGISFTCRLGRDQSVSVSVVLNVTFP 122
+ W +E V+ N + S + +S D G + + LNV P
Sbjct: 4019 ITWQKEGINVNTSGRNHAVLPSGGLQISRAVREDAGTYMCVAQNPAGTALGKIKLNVQVP 4078
Query: 123 PLLSGNDFQ-TVEEGSNVKLVCNVKANPQAQMMWYKNSSLLDLEKSRHQIQQTSESFQLS 181
P++S + + + + L C P + W+K+ + +E R Q+ S L
Sbjct: 4079 PVISPHLKEYVIAVDKPITLSCEADGLPPPDITWHKDGRAI-VESIR---QRVLSSGSLQ 4134
Query: 182 ITKVEKPDNGTYSCIAKSSLKTESLDFHLIV 212
I V+ D G Y+C+A + + S L V
Sbjct: 4135 IAFVQPGDAGHYTCMAANVAGSSSTSTKLTV 4165
Score = 34.3 bits (77), Expect = 0.11
Identities = 36/173 (20%), Positives = 64/173 (36%), Gaps = 12/173 (6%)
Query: 33 VNGKTENYILDTTPGSQASLICAVQNHTREEELLWYREE--------GRVDLKSGNKINS 84
+ G E L G+ SL+C + L+W ++ GRV + SG +
Sbjct: 2197 IGGSDELTQLTVIEGNLISLLCE-SSGIPPPNLIWKKKGSPVLTDSMGRVRILSGGRQLQ 2255
Query: 85 SSVCVSSISENDNGISFTCRLGRDQSVSVSVVLNVTFPPLLSGNDFQTVEEGSNVKLVCN 144
S+ S + + ++ + ++ V + T S V G ++ L C
Sbjct: 2256 ISIAEKSDAALYSCVASNVAGTAKKEYNLQVYIRPTITNSGSHPTEIIVTRGKSISLECE 2315
Query: 145 VKANPQAQMMWYKNSSLLDLEKSRHQIQQTSESFQLSITKVEKPDNGTYSCIA 197
V+ P + W K+ L K ++ E L + + D G Y C+A
Sbjct: 2316 VQGIPPPTVTWMKDGHPLIKAKG---VEILDEGHILQLKNIHVSDTGRYVCVA 2365
Score = 33.9 bits (76), Expect = 0.15
Identities = 23/80 (28%), Positives = 35/80 (43%), Gaps = 2/80 (2%)
Query: 117 LNVTFPPLLS-GNDFQTVEEGSNVKLVCNVKANPQAQMMWYKNSSLLDLEKSRHQIQQTS 175
L V PP ++ G TV L C P+ + W KN LL+++++++ + S
Sbjct: 3798 LQVHVPPSIAPGPTNMTVIVNVQTTLACEATGIPKPSINWRKNGHLLNVDQNQNSYRLLS 3857
Query: 176 ESFQLSITKVEKPDNGTYSC 195
S L I D TY C
Sbjct: 3858 -SGSLVIISPSVDDTATYEC 3876
Score = 32.7 bits (73), Expect = 0.33
Identities = 29/128 (22%), Positives = 55/128 (42%), Gaps = 7/128 (5%)
Query: 79 GNKINSSSVCVSSISENDNGISFTCRLGRDQSVSVS--VVLNVTFPPLLSGNDFQT-VEE 135
G +I SS ++ ++ +TC + R+ + S V L+V PP++ + V
Sbjct: 3943 GYRILSSGAIEILATQLNHAGRYTC-VARNAAGSAHRHVTLHVHEPPVIQPQPSELHVIL 4001
Query: 136 GSNVKLVCNVKANPQAQMMWYKNSSLLDLEKSRHQIQQTSESFQLSITKVEKPDNGTYSC 195
+ + L C P + W K ++ H + + L I++ + D GTY C
Sbjct: 4002 NNPILLPCEATGTPSPFITWQKEGINVNTSGRNHAVLPSGG---LQISRAVREDAGTYMC 4058
Query: 196 IAKSSLKT 203
+A++ T
Sbjct: 4059 VAQNPAGT 4066
Score = 32.3 bits (72), Expect = 0.43
Identities = 26/88 (29%), Positives = 40/88 (45%), Gaps = 4/88 (4%)
Query: 115 VVLNVTFPPLLSGNDFQ-TVEEGSNVKLVCNVKANPQAQMMWYK--NSSLLDLEKSRHQI 171
+ L+V PP+ ++E GSNV L C V+ P+ + W + N + S I
Sbjct: 785 ITLDVGSPPVFIQEPADVSMEIGSNVTLPCYVQGYPEPTIKWRRLDNMPIFSRPFSVSSI 844
Query: 172 QQTSESFQLSITKVEKPDNGTYSCIAKS 199
Q + L I + D GTY C A++
Sbjct: 845 SQL-RTGALFILNLWASDKGTYICEAEN 871
Score = 30.4 bits (67), Expect = 1.6
Identities = 20/93 (21%), Positives = 38/93 (40%), Gaps = 2/93 (2%)
Query: 122 PPLLSGNDFQTVEEGSNVKLVCNVKANPQAQMMWYKNSSLLDLEKSRHQIQQTSESFQLS 181
PP++ + TV G L C + + + W +N D+ + +T + L
Sbjct: 520 PPVIQVPNNVTVTPGERAVLTCLIISAVDYNLTWQRNDR--DVRLAEPARIRTLANLSLE 577
Query: 182 ITKVEKPDNGTYSCIAKSSLKTESLDFHLIVKD 214
+ V+ D G Y C+ S + + L V++
Sbjct: 578 LKSVKFNDAGEYHCMVSSEGGSSAASVFLTVQE 610
Score = 30.0 bits (66), Expect = 2.1
Identities = 30/101 (29%), Positives = 42/101 (41%), Gaps = 14/101 (13%)
Query: 107 RDQSVSVSVVL----NVTFPPLLSGNDFQTVEEGSNVKLVCNVKANPQAQMMWYKNSSLL 162
R SVS S ++ VT P G Q + + C+V + + + +N L
Sbjct: 417 RVSSVSFSSIVPDAPKVTMPEKTPGYYLQPGQ------IPCSVDSLLPFTLSFVRNGVTL 470
Query: 163 DLEKSRHQIQQTSESFQLSITKVEKPDNGTYSCIAKSSLKT 203
++ Q + S S L I KV D G Y CIA SS T
Sbjct: 471 GVD----QYLKESASVNLDIAKVTLSDEGFYECIAVSSAGT 507
>gi|11321597 kinase insert domain receptor precursor [Homo sapiens]
Length = 1356
Score = 53.1 bits (126), Expect = 2e-07
Identities = 37/127 (29%), Positives = 64/127 (50%), Gaps = 7/127 (5%)
Query: 123 PLLSGN-DFQTVEEGSNVKLVCNVKANPQAQMMWYKNSSLLDLEKSRHQIQQTSESFQLS 181
P ++GN + QT G ++++ C NP Q+MW+K++ L +E S ++ + + L+
Sbjct: 667 PTITGNLENQTTSIGESIEVSCTASGNPPPQIMWFKDNETL-VEDSGIVLKDGNRN--LT 723
Query: 182 ITKVEKPDNGTYSCIAKSSLKTESLDFHLIVKDKTVGVPIEPII---AACVVIFLTLCFG 238
I +V K D G Y+C A S L ++ I++ +E II A + +F L
Sbjct: 724 IRRVRKEDEGLYTCQACSVLGCAKVEAFFIIEGAQEKTNLEIIILVGTAVIAMFFWLLLV 783
Query: 239 LIARRKK 245
+I R K
Sbjct: 784 IILRTVK 790
Score = 35.4 bits (80), Expect = 0.051
Identities = 36/143 (25%), Positives = 65/143 (45%), Gaps = 24/143 (16%)
Query: 75 DLK--SGNKINS--SSVCVSSISENDNGISFTCRLGRDQSVSVSVVLNVTF------PPL 124
DLK SG+++ S++ + ++ +D G+ +TC S + N TF P +
Sbjct: 276 DLKTQSGSEMKKFLSTLTIDGVTRSDQGL-YTCAA----SSGLMTKKNSTFVRVHEKPFV 330
Query: 125 LSGNDFQTVEE---GSNVKLVCNVKANPQAQMMWYKNSSLLDLEKSRHQIQQTSESFQLS 181
G+ +++ E G V++ P ++ WYKN L+ S H I+ L+
Sbjct: 331 AFGSGMESLVEATVGERVRIPAKYLGYPPPEIKWYKNGIPLE---SNHTIK---AGHVLT 384
Query: 182 ITKVEKPDNGTYSCIAKSSLKTE 204
I +V + D G Y+ I + + E
Sbjct: 385 IMEVSERDTGNYTVILTNPISKE 407
>gi|75709184 contactin 3 [Homo sapiens]
Length = 1028
Score = 53.1 bits (126), Expect = 2e-07
Identities = 41/154 (26%), Positives = 68/154 (44%), Gaps = 8/154 (5%)
Query: 67 WYREEGRVDLKSGNKINSSSVCVSSISENDNGISFTCRLGRDQSVSVSVVLNVTFP-PLL 125
W + + L+ +I + ++ +S++S D+G+ + V S L V P
Sbjct: 351 WLKNGAALVLEERTQIENGALTISNLSVTDSGMFQCIAENKHGLVYSSAELKVVASAPDF 410
Query: 126 SGNDFQT---VEEGSNVKLVCNVKANPQAQMMWYKNSSLLDLEKSRHQIQQTSESFQLSI 182
S N + V+ GS V L C +A+P+A W K D+ H+ L I
Sbjct: 411 SKNPMKKLVQVQVGSLVSLDCKPRASPRALSSWKKG----DVSVQEHERISLLNDGGLKI 466
Query: 183 TKVEKPDNGTYSCIAKSSLKTESLDFHLIVKDKT 216
V K D GTY+C+A++ + HL+V + T
Sbjct: 467 ANVTKADAGTYTCMAENQFGKANGTTHLVVTEPT 500
Score = 44.7 bits (104), Expect = 8e-05
Identities = 45/178 (25%), Positives = 81/178 (45%), Gaps = 17/178 (9%)
Query: 47 GSQASLICAVQNHTREEELLWYREEGRVDLKSGNKI---NSSSVCVSSISENDNGISFTC 103
GS SL C + R L ++G V ++ +I N + ++++++ D G ++TC
Sbjct: 424 GSLVSLDCKPRASPRA---LSSWKKGDVSVQEHERISLLNDGGLKIANVTKADAG-TYTC 479
Query: 104 ----RLGRDQSVSVSVVLNVTFPPLLSGNDFQTVEEGSNVKLVCNVKANPQAQMM--WYK 157
+ G+ + VV T L N V G +V L C V+ +P ++ WY
Sbjct: 480 MAENQFGKANGTTHLVVTEPTRITLAPSN--MDVSVGESVILPCQVQHDPLLDIIFTWYF 537
Query: 158 NSSLLDLEKSRHQIQQT--SESFQLSITKVEKPDNGTYSCIAKSSLKTESLDFHLIVK 213
N +L D +K ++ S S L I ++ +G Y C+ ++ + + S LIV+
Sbjct: 538 NGALADFKKDGSHFEKVGGSSSGDLMIRNIQLKHSGKYVCMVQTGVDSVSSAADLIVR 595
Score = 37.4 bits (85), Expect = 0.013
Identities = 27/84 (32%), Positives = 38/84 (45%), Gaps = 10/84 (11%)
Query: 117 LNVTFPPLLSGNDFQTVEEGSNVKLVCNVKANPQAQMMWYKNSSLLDLEKSRHQIQQTSE 176
+ V FP L +GS VKL C NP Q+ W ++ L K I+
Sbjct: 229 IEVQFPETLPA------AKGSTVKLECFALGNPIPQINWRRSDGLPFSSK----IKLRKF 278
Query: 177 SFQLSITKVEKPDNGTYSCIAKSS 200
S L I ++ D G+Y CIA++S
Sbjct: 279 SGVLEIPNFQQEDAGSYECIAENS 302
Score = 36.2 bits (82), Expect = 0.030
Identities = 22/78 (28%), Positives = 31/78 (39%), Gaps = 2/78 (2%)
Query: 126 SGNDFQTVEEGSNVKLVCNVKANPQAQMMWYKNSSLLDLEKSRHQIQQTSESFQLSITKV 185
S + F E + L C + NP W N S D++ S + + + I
Sbjct: 33 SNSIFPVGSEDKKITLHCEARGNPSPHYRWQLNGS--DIDMSMEHRYKLNGGNLVVINPN 90
Query: 186 EKPDNGTYSCIAKSSLKT 203
D GTY C A +SL T
Sbjct: 91 RNWDTGTYQCFATNSLGT 108
Score = 32.3 bits (72), Expect = 0.43
Identities = 48/214 (22%), Positives = 83/214 (38%), Gaps = 35/214 (16%)
Query: 3 WKSSVIMQM-----GRFLLLVILFLPREMTSSVLTVNGKTENYILDTTPGSQASLICAVQ 57
WK +++ G LL +F+ +E ++S+ V + + L S
Sbjct: 5 WKQLILLSFIGCLGGELLLQGPVFI-KEPSNSIFPVGSEDKKITLHCEARGNPS------ 57
Query: 58 NHTREEELLWYREEGRVDLKSGN--KINSSSVCVSSISENDNGISFTCRLGRDQSVSVSV 115
H R W +D+ + K+N ++ V + + N + ++ C VS
Sbjct: 58 PHYR-----WQLNGSDIDMSMEHRYKLNGGNLVVINPNRNWDTGTYQCFATNSLGTIVSR 112
Query: 116 VLNVTFPPLLSGNDFQT-------VEEGSNVKLVCNVKANP-QAQMMWYKNS--SLLDLE 165
+ F L +F+T V EG V L+C + + W N S ++ +
Sbjct: 113 EAKLQFAYL---ENFKTKMRSTVSVREGQGVVLLCGPPPHSGELSYAWIFNEYPSFVEED 169
Query: 166 KSRHQIQQTSESFQLSITKVEKPDNGTYSCIAKS 199
R Q+T L I+KVE D G Y+C+ S
Sbjct: 170 SRRFVSQETGH---LYISKVEPSDVGNYTCVVTS 200
>gi|40254891 hypothetical protein FLJ20674 [Homo sapiens]
Length = 540
Score = 52.8 bits (125), Expect = 3e-07
Identities = 50/194 (25%), Positives = 85/194 (43%), Gaps = 8/194 (4%)
Query: 52 LICAVQNHTREEELLWYREEGRVDLKSGNKINSSSVCVSSISENDNGISFTCRLGRDQSV 111
L C + + LW E G V + +K+ + S +S+ T + +S
Sbjct: 243 LTCRWDGGYPDPDFLWIEEPGGV-IVGKSKLGVEMLSESQLSDGKKFKCVTSHIVGPES- 300
Query: 112 SVSVVLNVTFPPLLSGNDFQTVEEGSNVKLVCNVK-ANPQAQMMWYKNSSLLDL---EKS 167
S ++ + P LLS +T G NV L C V A P A+++W +N + ++ S
Sbjct: 301 GASCMVQIRGPSLLS-EPMKTCFTGGNVTLTCQVSGAYPPAKILWLRNLTQPEVIIQPSS 359
Query: 168 RHQIQQTSESFQLSITKVEKP-DNGTYSCIAKSSLKTESLDFHLIVKDKTVGVPIEPIIA 226
RH I Q ++ L+I + D G Y C A S + ++ L VK+ I I
Sbjct: 360 RHLITQDGQNSTLTIHNCSQDLDEGYYICRADSPVGVREMEIWLSVKEPLNIGGIVGTIV 419
Query: 227 ACVVIFLTLCFGLI 240
+ +++ L + GL+
Sbjct: 420 SLLLLGLAIISGLL 433
>gi|33519481 neural cell adhesion molecule 2 precursor [Homo
sapiens]
Length = 837
Score = 52.8 bits (125), Expect = 3e-07
Identities = 49/201 (24%), Positives = 89/201 (44%), Gaps = 34/201 (16%)
Query: 44 TTPGSQASLICAVQNHTREEELLWYRE-------------EGRVDLKSGNKINSSSVCVS 90
T Q +L+C + E + W R +GR+++K + SSS+ +
Sbjct: 312 TYENGQVTLVCDAEGEPIPE-ITWKRAVDGFTFTEGDKSLDGRIEVKGQH--GSSSLHIK 368
Query: 91 SISENDNGISFTC----RLGRDQSVSVSVVLNVTFPPLLSGNDFQTVE---EGSNVKLVC 143
+ +D+G + C R+G Q S+ L++ + P N QT+ EG+ + + C
Sbjct: 369 DVKLSDSG-RYDCEAASRIGGHQK---SMYLDIEYAPKFISN--QTIYYSWEGNPINISC 422
Query: 144 NVKANPQAQMMWYKNSSLLDLEKSRH-QIQQTSESFQLSITKVEKPDNGTYSCIAKSSLK 202
+VK+NP A + W ++ +L + + + + T L I D G Y+C A + +
Sbjct: 423 DVKSNPPASIHWRRDKLVLPAKNTTNLKTYSTGRKMILEIAPTSDNDFGRYNCTATNHIG 482
Query: 203 TESLDFHLIVKDKTVGVPIEP 223
T ++ L + D VP P
Sbjct: 483 TRFQEYILALAD----VPSSP 499
Score = 43.9 bits (102), Expect = 1e-04
Identities = 41/176 (23%), Positives = 79/176 (44%), Gaps = 24/176 (13%)
Query: 63 EELLWYREEGRVDLKSGNKINS-----SSVCVSSISENDNGISFTCRL--GRDQSVSVSV 115
E + WY +G + + + S + + + + D GI + C+ + Q+ +V
Sbjct: 49 ESIDWYNPQGEKIISTQRVVVQKEGVRSRLTIYNANIEDAGI-YRCQATDAKGQTQEATV 107
Query: 116 VLNV----TFPPLLSGNDFQTVEEGSNVKLVCNVKANPQAQMMW-YKNSSLLDLEKSRHQ 170
VL + TF ++S +F+ +G + ++VC V ++P + W Y N + + +R
Sbjct: 108 VLEIYQKLTFREVVSPQEFK---QGEDAEVVCRVSSSPAPAVSWLYHNEEVTTISDNRFA 164
Query: 171 IQQTSESFQLSITKVEKPDNGTYSCIAKSSLKTESLDFHLIVKDKTVGVPIEPIIA 226
+ + L I + K D G Y C + + E +DF +D V V + P I+
Sbjct: 165 MLANN---NLQILNINKSDEGIYRCEGRVEARGE-IDF----RDIIVIVNVPPAIS 212
Score = 43.1 bits (100), Expect = 2e-04
Identities = 37/161 (22%), Positives = 75/161 (46%), Gaps = 16/161 (9%)
Query: 47 GSQASLICAVQNHTREEELLWYREEGRVDLKSGNK---INSSSVCVSSISENDNGISFTC 103
G A ++C V + + + W V S N+ + ++++ + +I+++D GI + C
Sbjct: 129 GEDAEVVCRVSS-SPAPAVSWLYHNEEVTTISDNRFAMLANNNLQILNINKSDEGI-YRC 186
Query: 104 RLGRDQSVSV----SVVLNVTFPPLLS--GNDFQ-TVEEGSNVKLVCNVKANPQAQMMWY 156
GR ++ +++ V PP +S F T E G + C +P+ + W+
Sbjct: 187 E-GRVEARGEIDFRDIIVIVNVPPAISMPQKSFNATAERGEEMTFSCRASGSPEPAISWF 245
Query: 157 KNSSLLDLEKSRHQIQQTSESFQLSITKVEKPDNGTYSCIA 197
+N L +E++ I + S + +L++ + D G Y C A
Sbjct: 246 RNGKL--IEENEKYILKGSNT-ELTVRNIINSDGGPYVCRA 283
Score = 38.5 bits (88), Expect = 0.006
Identities = 47/214 (21%), Positives = 85/214 (39%), Gaps = 32/214 (14%)
Query: 16 LLVILFLPREMTSSVLTVNGKTENYILDTTPGSQASLICAVQNHTREEELLWYR------ 69
++VI+ +P ++ + N E G + + C + E + W+R
Sbjct: 201 IIVIVNVPPAISMPQKSFNATAER-------GEEMTFSCRASG-SPEPAISWFRNGKLIE 252
Query: 70 EEGRVDLKSGNKINSSSVCVSSISENDNGISFTCRL----GRDQSVSVSVVLNVTFPPLL 125
E + LK N + + V +I +D G + CR G D+ L V P +
Sbjct: 253 ENEKYILKGSN----TELTVRNIINSDGG-PYVCRATNKAGEDEK---QAFLQVFVQPHI 304
Query: 126 SGNDFQTVEEGSNVKLVCNVKANPQAQMMWYK---NSSLLDLEKS---RHQIQQTSESFQ 179
+T E V LVC+ + P ++ W + + + +KS R +++ S
Sbjct: 305 IQLKNETTYENGQVTLVCDAEGEPIPEITWKRAVDGFTFTEGDKSLDGRIEVKGQHGSSS 364
Query: 180 LSITKVEKPDNGTYSCIAKSSLKTESLDFHLIVK 213
L I V+ D+G Y C A S + +L ++
Sbjct: 365 LHIKDVKLSDSGRYDCEAASRIGGHQKSMYLDIE 398
>gi|193083163 roundabout, axon guidance receptor, homolog 2 isoform
ROBO2a [Homo sapiens]
Length = 1394
Score = 52.4 bits (124), Expect = 4e-07
Identities = 43/158 (27%), Positives = 71/158 (44%), Gaps = 12/158 (7%)
Query: 47 GSQASLICAVQNHTREEELLWYREEGRVDLKSGN-KINSSSVCVSSISENDNGISFTC-- 103
G A L C E + W +++ R+D K I + +S+ ++D G+ +TC
Sbjct: 163 GEPAILECQPPRGHPEPTIYWKKDKVRIDDKEERISIRGGKLMISNTRKSDAGM-YTCVG 221
Query: 104 --RLGRDQSVSVSVVLNVTFPPLLSGNDFQTVEEGSNVKLVCNVKANPQAQMMWYKNSSL 161
+G S + + P L Q V E V+ C V+ +PQ + W K+ +
Sbjct: 222 TNMVGERDSDPAELTV-FERPTFLRRPINQVVLEEEAVEFRCQVQGDPQPTVRWKKDDA- 279
Query: 162 LDLEKSRHQIQQTSESFQLSITKVEKPDNGTYSCIAKS 199
DL + R+ I+ + + L I K D GTY CIA++
Sbjct: 280 -DLPRGRYDIK---DDYTLRIKKTMSTDEGTYMCIAEN 313
Score = 44.3 bits (103), Expect = 1e-04
Identities = 44/177 (24%), Positives = 70/177 (39%), Gaps = 22/177 (12%)
Query: 54 CAVQNHTREEELLWYREE-----GRVDLKSGNKINSSSVCVSSISENDNGISFTCRLGRD 108
C VQ + + W +++ GR D+K + + D G R
Sbjct: 262 CQVQGDP-QPTVRWKKDDADLPRGRYDIKDDYTLR-----IKKTMSTDEGTYMCIAENRV 315
Query: 109 QSVSVSVVLNVTFPP--LLSGNDFQTVEEGSNVKLVCNVKANPQAQMMWYKNSSLLDLEK 166
+ S L V PP ++ D Q V +G V C K NPQ + W K S L
Sbjct: 316 GKMEASATLTVRAPPQFVVRPRD-QIVAQGRTVTFPCETKGNPQPAVFWQKEGSQNLLFP 374
Query: 167 SRHQIQQT----SESFQLSITKVEKPDNGTYSC----IAKSSLKTESLDFHLIVKDK 215
++ Q + S + L+IT +++ D G Y C +A S L L+ ++ D+
Sbjct: 375 NQPQQPNSRCSVSPTGDLTITNIQRSDAGYYICQALTVAGSILAKAQLEVTDVLTDR 431
Score = 40.0 bits (92), Expect = 0.002
Identities = 31/119 (26%), Positives = 54/119 (45%), Gaps = 13/119 (10%)
Query: 121 FPPLLSGNDFQT-VEEGSNVKLVCNVKANPQAQMMWYKNSSLLDLEK----SRHQIQQTS 175
FPP + + V +G L C + P + WYK+ ++ +K S + +
Sbjct: 45 FPPRIVEHPSDVIVSKGEPTTLNCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLPSG 104
Query: 176 ESFQLSIT--KVEKPDNGTYSCIAKSSL-----KTESLDFHLIVKDKTVGVPIEPIIAA 227
F L I + KPD G+Y C+A++ L + SL+ L+ +D P + ++AA
Sbjct: 105 SLFFLRIVHGRRSKPDEGSYVCVARNYLGEAVSRNASLEVALL-RDDFRQNPTDVVVAA 162
Score = 37.4 bits (85), Expect = 0.013
Identities = 32/124 (25%), Positives = 46/124 (37%), Gaps = 10/124 (8%)
Query: 84 SSSVCVSSISENDNGISFTCRLGRDQSVSVSVVLNVTF-------PPLLSGNDFQTVEEG 136
+ + +++I +D G L S+ L VT P +L G QT+
Sbjct: 389 TGDLTITNIQRSDAGYYICQALTVAGSILAKAQLEVTDVLTDRPPPIILQGPANQTLAVD 448
Query: 137 SNVKLVCNVKANPQAQMMWYKNSSLLDLEKSRHQIQQTSESFQLSITKVEKPDNGTYSCI 196
L C +P + W K R IQ E L I + D GTY+C+
Sbjct: 449 GTALLKCKATGDPLPVISWLKEGFTFPGRDPRATIQ---EQGTLQIKNLRISDTGTYTCV 505
Query: 197 AKSS 200
A SS
Sbjct: 506 ATSS 509
>gi|61888896 roundabout, axon guidance receptor, homolog 2 isoform
ROBO2b [Homo sapiens]
Length = 1378
Score = 52.4 bits (124), Expect = 4e-07
Identities = 43/158 (27%), Positives = 71/158 (44%), Gaps = 12/158 (7%)
Query: 47 GSQASLICAVQNHTREEELLWYREEGRVDLKSGN-KINSSSVCVSSISENDNGISFTC-- 103
G A L C E + W +++ R+D K I + +S+ ++D G+ +TC
Sbjct: 147 GEPAILECQPPRGHPEPTIYWKKDKVRIDDKEERISIRGGKLMISNTRKSDAGM-YTCVG 205
Query: 104 --RLGRDQSVSVSVVLNVTFPPLLSGNDFQTVEEGSNVKLVCNVKANPQAQMMWYKNSSL 161
+G S + + P L Q V E V+ C V+ +PQ + W K+ +
Sbjct: 206 TNMVGERDSDPAELTV-FERPTFLRRPINQVVLEEEAVEFRCQVQGDPQPTVRWKKDDA- 263
Query: 162 LDLEKSRHQIQQTSESFQLSITKVEKPDNGTYSCIAKS 199
DL + R+ I+ + + L I K D GTY CIA++
Sbjct: 264 -DLPRGRYDIK---DDYTLRIKKTMSTDEGTYMCIAEN 297
Score = 44.3 bits (103), Expect = 1e-04
Identities = 44/177 (24%), Positives = 70/177 (39%), Gaps = 22/177 (12%)
Query: 54 CAVQNHTREEELLWYREE-----GRVDLKSGNKINSSSVCVSSISENDNGISFTCRLGRD 108
C VQ + + W +++ GR D+K + + D G R
Sbjct: 246 CQVQGDP-QPTVRWKKDDADLPRGRYDIKDDYTLR-----IKKTMSTDEGTYMCIAENRV 299
Query: 109 QSVSVSVVLNVTFPP--LLSGNDFQTVEEGSNVKLVCNVKANPQAQMMWYKNSSLLDLEK 166
+ S L V PP ++ D Q V +G V C K NPQ + W K S L
Sbjct: 300 GKMEASATLTVRAPPQFVVRPRD-QIVAQGRTVTFPCETKGNPQPAVFWQKEGSQNLLFP 358
Query: 167 SRHQIQQT----SESFQLSITKVEKPDNGTYSC----IAKSSLKTESLDFHLIVKDK 215
++ Q + S + L+IT +++ D G Y C +A S L L+ ++ D+
Sbjct: 359 NQPQQPNSRCSVSPTGDLTITNIQRSDAGYYICQALTVAGSILAKAQLEVTDVLTDR 415
Score = 40.0 bits (92), Expect = 0.002
Identities = 31/119 (26%), Positives = 54/119 (45%), Gaps = 13/119 (10%)
Query: 121 FPPLLSGNDFQT-VEEGSNVKLVCNVKANPQAQMMWYKNSSLLDLEK----SRHQIQQTS 175
FPP + + V +G L C + P + WYK+ ++ +K S + +
Sbjct: 29 FPPRIVEHPSDVIVSKGEPTTLNCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLPSG 88
Query: 176 ESFQLSIT--KVEKPDNGTYSCIAKSSL-----KTESLDFHLIVKDKTVGVPIEPIIAA 227
F L I + KPD G+Y C+A++ L + SL+ L+ +D P + ++AA
Sbjct: 89 SLFFLRIVHGRRSKPDEGSYVCVARNYLGEAVSRNASLEVALL-RDDFRQNPTDVVVAA 146
Score = 37.4 bits (85), Expect = 0.013
Identities = 32/124 (25%), Positives = 46/124 (37%), Gaps = 10/124 (8%)
Query: 84 SSSVCVSSISENDNGISFTCRLGRDQSVSVSVVLNVTF-------PPLLSGNDFQTVEEG 136
+ + +++I +D G L S+ L VT P +L G QT+
Sbjct: 373 TGDLTITNIQRSDAGYYICQALTVAGSILAKAQLEVTDVLTDRPPPIILQGPANQTLAVD 432
Query: 137 SNVKLVCNVKANPQAQMMWYKNSSLLDLEKSRHQIQQTSESFQLSITKVEKPDNGTYSCI 196
L C +P + W K R IQ E L I + D GTY+C+
Sbjct: 433 GTALLKCKATGDPLPVISWLKEGFTFPGRDPRATIQ---EQGTLQIKNLRISDTGTYTCV 489
Query: 197 AKSS 200
A SS
Sbjct: 490 ATSS 493
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 52.0 bits (123), Expect = 5e-07
Identities = 48/199 (24%), Positives = 95/199 (47%), Gaps = 15/199 (7%)
Query: 27 TSSVL---TVNGKTENYILDTTPGSQASLICAVQNHTREEELLWYREEGRVDLKSGNKIN 83
T SVL T+ K E+ + T G +L C V T E W+++ + + KI+
Sbjct: 7579 TLSVLEPATIVEKPES--IKVTTGDTCTLECTVAG-TPELSTKWFKDGKELTSDNKYKIS 7635
Query: 84 S----SSVCVSSISENDNGI-SFTCR--LGRDQSVSVSVVLNVTFPPLLSGNDFQTVE-E 135
S + + +++ +D+G+ SF + +G+D + V + T PP + +T
Sbjct: 7636 FFNKVSGLKIINVAPSDSGVYSFEVQNPVGKDSCTASLQVSDRTVPPSFTRKLKETNGLS 7695
Query: 136 GSNVKLVCNVKANPQAQMMWYKNSSLLDLEKSRHQIQQTSESFQLSITKVEKPDNGTYSC 195
GS+V + C V +P + W+ + + + ++Q T + L++ +E+ D+G Y+C
Sbjct: 7696 GSSVVMECKVYGSPPISVSWFHEGNEISSGR-KYQTTLTDNTCALTVNMLEESDSGDYTC 7754
Query: 196 IAKSSLKTESLDFHLIVKD 214
IA + ++ L V++
Sbjct: 7755 IATNMAGSDECSAPLTVRE 7773
Score = 51.2 bits (121), Expect = 9e-07
Identities = 46/197 (23%), Positives = 80/197 (40%), Gaps = 16/197 (8%)
Query: 42 LDTTPGSQASLICAVQNHTREEELLWYR------EEGRVDLKSGNKINSSSVCVSSISEN 95
L+ G A C +Q+ W++ E + ++S I+S + + + +
Sbjct: 3465 LEVALGHLAKFTCEIQS-APNVRFQWFKAGREIYESDKCSIRSSKYISSLEILRTQVVDC 3523
Query: 96 DNGISFTCRLGRDQ-SVSVSVVLNVT--FPP-LLSGNDFQTVEEGSNVKLVCNVKANPQA 151
+TC+ + SVS + L VT +PP LS T G K +C V P
Sbjct: 3524 GE---YTCKASNEYGSVSCTATLTVTEAYPPTFLSRPKSLTTFVGKAAKFICTVTGTPVI 3580
Query: 152 QMMWYKNSSLLDLEKSRHQIQQTSESFQLSITKVEKPDNGTYSCIAKSSLKTESLDFHLI 211
+ +W K+ + L +I L ++ + D G YSC A + + LI
Sbjct: 3581 ETIWQKDGAALS-PSPNWRISDAENKHILELSNLTIQDRGVYSCKASNKFGADICQAELI 3639
Query: 212 VKDKTVGV-PIEPIIAA 227
+ DK + +EP+ +A
Sbjct: 3640 IIDKPHFIKELEPVQSA 3656
Score = 51.2 bits (121), Expect = 9e-07
Identities = 45/183 (24%), Positives = 82/183 (44%), Gaps = 18/183 (9%)
Query: 43 DTTPGSQASLICAVQNHTREEELLWYREEGRVDLKSGNKINSSSVCVSS------ISEND 96
D PGS L Q T + W++ G +L SG + + S + +D
Sbjct: 4216 DVLPGSAVCLKSTFQGST-PLTIRWFK--GNKELVSGGSCYITKEALESSLELYLVKTSD 4272
Query: 97 NGISFTCRL-----GRDQSVSVSVVLNVTFPPLLSGNDFQTVEEGSNVKLVCNVKANPQA 151
+G ++TC++ G + S ++ V TF L + Q +++G +L C V P
Sbjct: 4273 SG-TYTCKVSNVAGGVECSANLFVKEPATFVEKLEPS--QLLKKGDATQLACKVTGTPPI 4329
Query: 152 QMMWYKNSSLLDLEKSRHQIQQTSESFQLSITKVEKPDNGTYSCIAKSSLKTESLDFHLI 211
++ W+ N + E S+H++ + L +T V D+G Y C A++ ++ +I
Sbjct: 4330 KITWFANDREIK-ESSKHRMSFVESTAVLRLTDVGIEDSGEYMCEAQNEAGSDHCSSIVI 4388
Query: 212 VKD 214
VK+
Sbjct: 4389 VKE 4391
Score = 50.8 bits (120), Expect = 1e-06
Identities = 46/181 (25%), Positives = 79/181 (43%), Gaps = 14/181 (7%)
Query: 47 GSQASLICAVQNHTREEELLWYREEGRVDLKSGNKI----NSSSVCVSSISENDNGISFT 102
G A+L C V T E + WY+E ++ K+ N +S+ ++ + +D G ++
Sbjct: 7034 GEPATLQCKVDG-TPEIRISWYKEHTKLRSAPAYKMQFKNNVASLVINKVDHSDVG-EYS 7091
Query: 103 CR----LGRDQSVSVSVVLNVTFPPLLSGNDFQTVEE--GSNVKLVCNVKANPQAQMMWY 156
C+ +G S +V V+ PP + + V E G V C + + Q+ WY
Sbjct: 7092 CKADNSVGAVASSAVLVIKARKLPPFFA-RKLKDVHETLGFPVAFECRINGSEPLQVSWY 7150
Query: 157 KNSSLLDLEKSRHQIQQTSESFQLSITKVEKPDNGTYSCIAKSSLKTESLDFHLIVKDKT 216
K+ LL + + Q L I + ++ G Y+C A + L T S LI+ +
Sbjct: 7151 KDGVLLK-DDANLQTSFVHNVATLQILQTDQSHIGQYNCSASNPLGTASSSAKLILSEHE 7209
Query: 217 V 217
V
Sbjct: 7210 V 7210
Score = 49.7 bits (117), Expect = 3e-06
Identities = 43/158 (27%), Positives = 68/158 (43%), Gaps = 18/158 (11%)
Query: 67 WYREEGRVDLKSGNKI------NSSSVCVSSISENDNGISFTC----RLGRDQSVSVSVV 116
W+ E ++ SG K N+ ++ V+ + E+D+G +TC G D+ S
Sbjct: 7715 WFHEGN--EISSGRKYQTTLTDNTCALTVNMLEESDSG-DYTCIATNMAGSDEC---SAP 7768
Query: 117 LNVTFPP-LLSGNDFQTVEEGSNVKLVCNVKANPQAQMMWYKNSSLLDLEKSRHQIQQTS 175
L V PP + D V G+NV VK P + W+K SS L + R +
Sbjct: 7769 LTVREPPSFVQKPDPMDVLTGTNVTFTSIVKGTPPFSVSWFKGSSEL-VPGDRCNVSLED 7827
Query: 176 ESFQLSITKVEKPDNGTYSCIAKSSLKTESLDFHLIVK 213
+L + V+ +G Y+CI + S HL +K
Sbjct: 7828 SVAELELFDVDTSQSGEYTCIVSNEAGKASCTTHLYIK 7865
Score = 49.3 bits (116), Expect = 3e-06
Identities = 33/122 (27%), Positives = 61/122 (50%), Gaps = 5/122 (4%)
Query: 96 DNGISFTCRLGRDQ-SVSVSVVLNVTFPP--LLSGNDFQTVEEGSNVKLVCNVKANPQAQ 152
D+G ++ C + S S S + V PP + + + G + +L C +K +P Q
Sbjct: 3710 DSG-TYVCTASNEAGSSSCSATVTVREPPSFVKKVDPSYLMLPGESARLHCKLKGSPVIQ 3768
Query: 153 MMWYKNSSLLDLEKSRHQIQQTSESFQLSITKVEKPDNGTYSCIAKSSLKTESLDFHLIV 212
+ W+KN+ L + SE+ L IT V+ D+G+YSC A + + ++S +++
Sbjct: 3769 VTWFKNNKELSESNTVRMYFVNSEAI-LDITDVKVEDSGSYSCEAVNDVGSDSCSTEIVI 3827
Query: 213 KD 214
K+
Sbjct: 3828 KE 3829
Score = 48.5 bits (114), Expect = 6e-06
Identities = 40/180 (22%), Positives = 86/180 (47%), Gaps = 13/180 (7%)
Query: 55 AVQNHTREEELLWYREEGRVDLKSGNKI------NSSSVCVSSISENDNGISFTCRLGRD 108
A+ T ++ W++++ V+L SG K ++S + + S+ + G +TC + D
Sbjct: 5351 AILKGTPPFKIKWFKDD--VELVSGPKCFIGLEGSTSFLNLYSVDASKTG-QYTCHVTND 5407
Query: 109 Q-SVSVSVVLNVTFPP--LLSGNDFQTVEEGSNVKLVCNVKANPQAQMMWYKNSSLLDLE 165
S S + +L VT PP + + V+ G + +L C + +P+ +++W++N L
Sbjct: 5408 VGSDSCTTMLLVTEPPKFVKKLEASKIVKAGDSSRLECKIAGSPEIRVVWFRNEHELP-A 5466
Query: 166 KSRHQIQQTSESFQLSITKVEKPDNGTYSCIAKSSLKTESLDFHLIVKDKTVGVPIEPII 225
++++ + + + D+G + C A++ + S +IVK+ V PI+
Sbjct: 5467 SDKYRMTFIDSVAVIQMNNLSTEDSGDFICEAQNPAGSTSCSTKVIVKEPPVFSSFPPIV 5526
Score = 48.5 bits (114), Expect = 6e-06
Identities = 40/159 (25%), Positives = 68/159 (42%), Gaps = 7/159 (4%)
Query: 65 LLWYREEGRVDLKSGNK----INSSSVCVSSISENDNGISFTCRLGRDQSV-SVSVVLNV 119
++W ++ G V +S N I++ + E N + C++ D + S VL V
Sbjct: 6582 VVWLKDRGEVIRESENTRISFIDNIATLQLGSPEASNSGKYICQIKNDAGMRECSAVLTV 6641
Query: 120 TFPP-LLSGNDFQTVEEGSNVKLVCNVKANPQAQMMWYKNSSLLDLEKSRHQIQQTSESF 178
P ++ + TV G+ L C V P+ W+K+ L + S+H I ++
Sbjct: 6642 LEPARIIEKPEPMTVTTGNPFALECVVTGTPELSAKWFKDGRELSAD-SKHHITFINKVA 6700
Query: 179 QLSITKVEKPDNGTYSCIAKSSLKTESLDFHLIVKDKTV 217
L I E D G YS K+S+ + + V D+ V
Sbjct: 6701 SLKIPCAEMSDKGLYSFEVKNSVGKSNCTVSVHVSDRIV 6739
Score = 47.4 bits (111), Expect = 1e-05
Identities = 38/179 (21%), Positives = 77/179 (43%), Gaps = 10/179 (5%)
Query: 42 LDTTPGSQASLICAVQNHTREEELLWYREEGRVDLKSGNKI----NSSSVCVSSISENDN 97
+D G A C V + + W ++ + I N+ + + + + D+
Sbjct: 6280 IDVIAGESADFECHVTG-AQPMRITWSKDNKEIRPGGNYTITCVGNTPHLRILKVGKGDS 6338
Query: 98 GISFTCRLGRDQSVSV-SVVLNVTFPP--LLSGNDFQTVEEGSNVKLVCNVKANPQAQMM 154
G +TC+ D + S L+V PP + + ++G +++L C + +P+ ++
Sbjct: 6339 G-QYTCQATNDVGKDMCSAQLSVKEPPKFVKKLEASKVAKQGESIQLECKISGSPEIKVS 6397
Query: 155 WYKNSSLLDLEKSRHQIQQTSESFQLSITKVEKPDNGTYSCIAKSSLKTESLDFHLIVK 213
W++N S L E ++ + + L+I + D+G Y C A + + S L VK
Sbjct: 6398 WFRNDSELH-ESWKYNMSFINSVALLTINEASAEDSGDYICEAHNGVGDASCSTALTVK 6455
Score = 47.4 bits (111), Expect = 1e-05
Identities = 40/182 (21%), Positives = 80/182 (43%), Gaps = 8/182 (4%)
Query: 42 LDTTPGSQASLICAVQNHTREEELLWYREEGRVDLKSGNKINSSSVCVSSIS----ENDN 97
+ T G + L ++ ++W++++G + +S N S S ++++ E N
Sbjct: 7501 ISTVVGKEVQLQTTIEG-AEPISVVWFKDKGEIVRESDNIWISYSENIATLQFSRVEPAN 7559
Query: 98 GISFTCRLGRDQSVSVS-VVLNVTFPP-LLSGNDFQTVEEGSNVKLVCNVKANPQAQMMW 155
+TC++ D + L+V P ++ + V G L C V P+ W
Sbjct: 7560 AGKYTCQIKNDAGMQECFATLSVLEPATIVEKPESIKVTTGDTCTLECTVAGTPELSTKW 7619
Query: 156 YKNSSLLDLEKSRHQIQQTSESFQLSITKVEKPDNGTYSCIAKSSLKTESLDFHLIVKDK 215
+K+ L + ++++I ++ L I V D+G YS ++ + +S L V D+
Sbjct: 7620 FKDGKELTSD-NKYKISFFNKVSGLKIINVAPSDSGVYSFEVQNPVGKDSCTASLQVSDR 7678
Query: 216 TV 217
TV
Sbjct: 7679 TV 7680
Score = 47.4 bits (111), Expect = 1e-05
Identities = 42/185 (22%), Positives = 80/185 (43%), Gaps = 17/185 (9%)
Query: 42 LDTTPGSQASLICAVQNHTREEELLWYREEGRVDLKSGNKI------NSSSVCVSSISEN 95
+D G A C V T+ ++ W ++ +++SG K NS+ + V + +
Sbjct: 8162 VDAVVGESADFECHVTG-TQPIKVSWAKDSR--EIRSGGKYQISYLENSAHLTVLKVDKG 8218
Query: 96 DNGISFTC----RLGRDQSVSVSVVLNVTFPPLLSGNDFQTVEE--GSNVKLVCNVKANP 149
D+G +TC +G+D + + PP + +TVEE G++ KL V +
Sbjct: 8219 DSG-QYTCYAVNEVGKDSCTAQLNIKERLIPPSFTKRLSETVEETEGNSFKLEGRVAGSQ 8277
Query: 150 QAQMMWYKNSSLLDLEKSRHQIQQTSESFQLSITKVEKPDNGTYSCIAKSSLKTESLDFH 209
+ WYKN+ + S +I + + L + K D G Y+C + +
Sbjct: 8278 PITVAWYKNNIEIQ-PTSNCEITFKNNTLVLQVRKAGMNDAGLYTCKVSNDAGSALCTSS 8336
Query: 210 LIVKD 214
+++K+
Sbjct: 8337 IVIKE 8341
Score = 45.8 bits (107), Expect = 4e-05
Identities = 31/107 (28%), Positives = 50/107 (46%), Gaps = 5/107 (4%)
Query: 96 DNGISFTCRLGRDQ-SVSVSVVLNVTFPPLLSGNDFQTVE--EGSNVKLVCNVKANPQAQ 152
+N ++ C D + S S+ L V PP + + VE + S+V+L C V P +
Sbjct: 4927 ENSGTYVCEARNDAGTASCSIELKVKEPPTFI-RELKPVEVVKYSDVELECEVTGTPPFE 4985
Query: 153 MMWYKNSSLLDLEKSRHQIQQTSESFQLSITKVEKPDNGTYSCIAKS 199
+ W KN+ + K ++ + F L ITK + D G Y CI +
Sbjct: 4986 VTWLKNNREIRSSK-KYTLTDRVSVFNLHITKCDPSDTGEYQCIVSN 5031
Score = 45.8 bits (107), Expect = 4e-05
Identities = 39/163 (23%), Positives = 69/163 (42%), Gaps = 11/163 (6%)
Query: 67 WYREEGRVDLKSGNKI----NSSSVCVSSISENDNGISFTCRLGRDQSVSV---SVVLNV 119
WY+ + S +I N+ + V ND G+ +TC++ D ++ S+V+
Sbjct: 8283 WYKNNIEIQPTSNCEITFKNNTLVLQVRKAGMNDAGL-YTCKVSNDAGSALCTSSIVIKE 8341
Query: 120 TFPPLLSGNDFQ--TVEEGSNVKLVCNVKANPQAQMMWYKNSSLLDLEKSRHQIQQTSES 177
P + TV EG V+L C+V+ + ++ W K + R S +
Sbjct: 8342 PKKPPVFDQHLTPVTVSEGEYVQLSCHVQGSEPIRIQWLKAGREIK-PSDRCSFSFASGT 8400
Query: 178 FQLSITKVEKPDNGTYSCIAKSSLKTESLDFHLIVKDKTVGVP 220
L + V K D+G Y C A + +++ + +KDK P
Sbjct: 8401 AVLELRDVAKADSGDYVCKASNVAGSDTTKSKVTIKDKPAVAP 8443
Score = 45.4 bits (106), Expect = 5e-05
Identities = 42/182 (23%), Positives = 83/182 (45%), Gaps = 12/182 (6%)
Query: 42 LDTTPGSQASLICAVQNHTREEELLWYREEGRVDLKSGNKINSSSVC----VSSISENDN 97
+D T G A+L T+E W+++ + L S KI+ + + S + D+
Sbjct: 4588 IDVTQGDPATLQVKFSG-TKEITAKWFKDGQELTLGSKYKISVTDTVSILKIISTEKKDS 4646
Query: 98 G-ISFTCR--LGRDQSVSVSVVLNVTFPPLLSGNDFQTVE--EGSNVKLVCNVKANPQAQ 152
G +F + +GR + VL++ PP + + ++ +GS + L C V +
Sbjct: 4647 GEYTFEVQNDVGRSSCKARINVLDLIIPPSFT-KKLKKMDSIKGSFIDLECIVAGSHPIS 4705
Query: 153 MMWYKNSSLLDLEKSRHQIQQTSESFQLSITKVEKPDNGTYSCIAKSSLKTESLDFHLIV 212
+ W+K+ + + +++ + L I+++E D+GTY+C A + HL V
Sbjct: 4706 IQWFKDDQEISASE-KYKFSFHDNTAFLEISQLEGTDSGTYTCSATNKAGHNQCSGHLTV 4764
Query: 213 KD 214
K+
Sbjct: 4765 KE 4766
Score = 45.4 bits (106), Expect = 5e-05
Identities = 35/157 (22%), Positives = 67/157 (42%), Gaps = 7/157 (4%)
Query: 67 WYREEGRVDLKSGNK----INSSSVCVSSISENDNGISFTCRLGRDQSVSVSVVLNVTFP 122
W +E+ V +S N + + + + +E N + C++ D + ++ +
Sbjct: 5643 WLKEKEEVIRESENIRITFVENVATLQFAKAEPANAGKYICQIKNDGGMRENMATLMVLE 5702
Query: 123 P--LLSGNDFQTVEEGSNVKLVCNVKANPQAQMMWYKNSSLLDLEKSRHQIQQTSESFQL 180
P ++ TV G L C V P+ + WYK+ LL +H+ ++ L
Sbjct: 5703 PAVIVEKAGPMTVTVGETCTLECKVAGTPELSVEWYKDGKLL-TSSQKHKFSFYNKISSL 5761
Query: 181 SITKVEKPDNGTYSCIAKSSLKTESLDFHLIVKDKTV 217
I VE+ D GTY+ ++++ S + V D+ V
Sbjct: 5762 RILSVERQDAGTYTFQVQNNVGKSSCTAVVDVSDRAV 5798
Score = 45.4 bits (106), Expect = 5e-05
Identities = 41/151 (27%), Positives = 62/151 (41%), Gaps = 14/151 (9%)
Query: 77 KSGNKINSSSVCVSSISEN------------DNGISFTCRLGRDQSVSVSVVLNVTFPPL 124
+ GN+I S C SS SEN D GI S S VL V PP
Sbjct: 6776 QDGNEIVSGPKCQSSFSENVCTLNLSLLEPSDTGIYTCVAANVAGSDECSAVLTVQEPPS 6835
Query: 125 LSGN-DFQTVEEGSNVKLVCNVKANPQAQMMWYKNSSLLDLEKSRHQIQQTSESFQLSIT 183
D V G ++ ++ P ++ W+K S L +S + I +L +
Sbjct: 6836 FEQTPDSVEVLPGMSLTFTSVIRGTPPFKVKWFKGSRELVPGESCN-ISLEDFVTELELF 6894
Query: 184 KVEKPDNGTYSCIAKSSLKTESLDFHLIVKD 214
+V+ ++G YSC+ + + S HL VK+
Sbjct: 6895 EVQPLESGDYSCLVTNDAGSASCTTHLFVKE 6925
Score = 45.1 bits (105), Expect = 6e-05
Identities = 31/103 (30%), Positives = 48/103 (46%), Gaps = 1/103 (0%)
Query: 111 VSVSVVLNVTFPPLLSGNDFQTVEEGSNVKLVCNVKANPQAQMMWYKNSSLLDLEKSRHQ 170
V V + VT P L+SG TV EG +V L C++ P + WY+ ++ Q
Sbjct: 932 VPAPVEIPVTPPTLVSGLKNVTVIEGESVTLECHISGYPSPTVTWYREDYQIE-SSIDFQ 990
Query: 171 IQQTSESFQLSITKVEKPDNGTYSCIAKSSLKTESLDFHLIVK 213
I S +L I + D+G ++C A + T S +L V+
Sbjct: 991 ITFQSGIARLMIREAFAEDSGRFTCSAVNEAGTVSTSCYLAVQ 1033
Score = 45.1 bits (105), Expect = 6e-05
Identities = 39/180 (21%), Positives = 78/180 (43%), Gaps = 12/180 (6%)
Query: 43 DTTPGSQASLICAVQNHTREEELLWYREEGRVDLKSGNKI----NSSSVCVSSISENDNG 98
D P ++ L V T + W+++ + + + S+S+ + + D+G
Sbjct: 4778 DVNPNTRVQLKALVGG-TAPMTIKWFKDNKELHSGAARSVWKDDTSTSLELFAAKATDSG 4836
Query: 99 ISFTCRLGRDQSVSVS-VVLNVTFPP--LLSGNDFQTVEEGSNVKLVCNVKANPQAQMMW 155
++ C+L D + S L V PP + + + G + C + P+ ++ W
Sbjct: 4837 -TYICQLSNDVGTATSKATLFVKEPPQFIKKPSPVLVLRNGQSTTFECQITGTPKIRVSW 4895
Query: 156 YKNSS-LLDLEKSRHQIQQTSESFQLSITKVEKPDNGTYSCIAKSSLKTESLDFHLIVKD 214
Y + + + ++K +FQ+S +VE ++GTY C A++ T S L VK+
Sbjct: 4896 YLDGNEITAIQKHGISFIDGLATFQISGARVE--NSGTYVCEARNDAGTASCSIELKVKE 4953
Score = 45.1 bits (105), Expect = 6e-05
Identities = 41/167 (24%), Positives = 77/167 (46%), Gaps = 13/167 (7%)
Query: 47 GSQASLICAVQNHTREEELLWYREEGRVDLKSGNK---INSSSVC-VSSISENDNGISFT 102
G + L C + + E ++W+R E + + I+S +V ++++S D+G F
Sbjct: 5438 GDSSRLECKIAG-SPEIRVVWFRNEHELPASDKYRMTFIDSVAVIQMNNLSTEDSG-DFI 5495
Query: 103 CRLGRDQ-SVSVSVVLNVTFPPLLSGNDFQTVEE---GSNVKLVCNVKANPQAQMMWYKN 158
C S S S + V PP+ S F + E + V L C + P +++WYK+
Sbjct: 5496 CEAQNPAGSTSCSTKVIVKEPPVFSS--FPPIVETLKNAEVSLECELSGTPPFEVVWYKD 5553
Query: 159 SSLLDLEKSRHQIQQTSESFQLSITKVEKPDNGTYSCIAKSSLKTES 205
L K +++I + + I V+ D G Y C A++ + +++
Sbjct: 5554 KRQLRSSK-KYKIASKNFHTSIHILNVDTSDIGEYHCKAQNEVGSDT 5599
Score = 44.7 bits (104), Expect = 8e-05
Identities = 33/131 (25%), Positives = 57/131 (43%), Gaps = 7/131 (5%)
Query: 80 NKINSSSVCVSSI---SENDNGISFTCRLGRDQSVSVSVVLNVTFPPLLSGNDFQTVEE- 135
N + + C+ I ++ D G ++C + + V L T P + + +E
Sbjct: 6033 NIVTTEKTCILEILNSTKRDAG-QYSCEIENEAGRDVCGALVSTLEPPYFVTELEPLEAA 6091
Query: 136 -GSNVKLVCNVKANPQAQMMWYKNSSLLDLEKSRHQIQQTSESFQLSITKVEKPDNGTYS 194
G +V L C V P+ + WYK + L ++ T+ L KV D+G Y+
Sbjct: 6092 VGDSVSLQCQVAGTPEITVSWYKGDTKL-RPTPEYRTYFTNNVATLVFNKVNINDSGEYT 6150
Query: 195 CIAKSSLKTES 205
C A++S+ T S
Sbjct: 6151 CKAENSIGTAS 6161
Score = 44.7 bits (104), Expect = 8e-05
Identities = 32/112 (28%), Positives = 50/112 (44%), Gaps = 13/112 (11%)
Query: 122 PPLLSGNDFQTVEEGSNVKLVCNVKANPQAQMMWY---------KNSSLLDLEKSRHQIQ 172
PP + +F VEEG+NV +V +K P + W+ K L D ++ +
Sbjct: 16117 PPSIDLKEFMEVEEGTNVNIVAKIKGVPFPTLTWFKAPPKKPDNKEPVLYDTHVNKLVVD 16176
Query: 173 QTSESFQLSITKVEKPDNGTYSCIAKSSLKTESLDFHLIVKDKTVGVPIEPI 224
T L I + + D G Y+ A ++L T S + L V + G P+ PI
Sbjct: 16177 DTC---TLVIPQSRRSDTGLYTITAVNNLGTASKEMRLNVLGRP-GPPVGPI 16224
Score = 44.7 bits (104), Expect = 8e-05
Identities = 22/86 (25%), Positives = 39/86 (45%), Gaps = 1/86 (1%)
Query: 132 TVEEGSNVKLVCNVKANPQAQMMWYKNSSLLDLEKSRHQIQQTSESFQLSITKVEKPDNG 191
TV EG + + C+ P + W + +L +RHQ+ T I+ V+ D G
Sbjct: 32571 TVYEGESARFSCDTDGEPVPTVTWLRKGQVLSTS-ARHQVTTTKYKSTFEISSVQASDEG 32629
Query: 192 TYSCIAKSSLKTESLDFHLIVKDKTV 217
YS + ++S + +F L ++ V
Sbjct: 32630 NYSVVVENSEGKQEAEFTLTIQKARV 32655
Score = 43.9 bits (102), Expect = 1e-04
Identities = 29/124 (23%), Positives = 53/124 (42%), Gaps = 10/124 (8%)
Query: 83 NSSSVCVSSISENDNGISFTCRLGRDQSVSVSVVLNVTF-------PPLLSGNDFQTVEE 135
+ ++ + S D GI TC + + + V ++T P +S Q + E
Sbjct: 33090 SDQTLTIKQASHRDEGI-LTC-ISKTKEGIVKCQYDLTLSKELSDAPAFISQPRSQNINE 33147
Query: 136 GSNVKLVCNVKANPQAQMMWYKNSSLLDLEKSRHQIQQTSESFQLSITKVEKPDNGTYSC 195
G NV C + P ++ W+KN+ + + S I ++ + L I D+G Y+
Sbjct: 33148 GQNVLFTCEISGEPSPEIEWFKNNLPISI-SSNVSISRSRNVYSLEIRNASVSDSGKYTI 33206
Query: 196 IAKS 199
AK+
Sbjct: 33207 KAKN 33210
Score = 42.7 bits (99), Expect = 3e-04
Identities = 39/186 (20%), Positives = 81/186 (43%), Gaps = 16/186 (8%)
Query: 42 LDTTPGSQASLICAVQNHTREEELLWYREEGRVDLKSGNKI----NSSSVCVSSISENDN 97
+D G + C V T ++ W ++ + K+ N++++ V + + D
Sbjct: 7221 VDLALGESGTFKCHVTG-TAPIKITWAKDNREIRPGGNYKMTLVENTATLTVLKVGKGDA 7279
Query: 98 GISFTCRL----GRDQSVSVSVVLNVTFPP--LLSGNDFQTVEEGSNVKLVCNVKANPQA 151
G +TC G+D S S L V PP + + V++ + C + +P+
Sbjct: 7280 G-QYTCYASNIAGKD---SCSAQLGVQEPPRFIKKLEPSRIVKQDEFTRYECKIGGSPEI 7335
Query: 152 QMMWYKNSSLLDLEKSRHQIQQTSESFQLSITKVEKPDNGTYSCIAKSSLKTESLDFHLI 211
+++WYK+ + + E S+ ++ L + + D+G Y+C A ++ + S L
Sbjct: 7336 KVLWYKDETEIQ-ESSKFRMSFVDSVAVLEMHNLSVEDSGDYTCEAHNAAGSASSSTSLK 7394
Query: 212 VKDKTV 217
VK+ +
Sbjct: 7395 VKEPPI 7400
Score = 42.4 bits (98), Expect = 4e-04
Identities = 48/213 (22%), Positives = 78/213 (36%), Gaps = 52/213 (24%)
Query: 50 ASLICAVQNHT-REEELLWYRE----------------EGRVDLKSGNKINSSS---VC- 88
A L C V++ R +E+ WY++ +G +LK N S VC
Sbjct: 32733 AKLTCVVESSVLRAKEVTWYKDGKKLKENGHFQFHYSADGTYELKINNLTESDQGEYVCE 32792
Query: 89 ------------------VSSISENDNGISFTCRLGRDQSVSVSVVLNVTFPP------- 123
SI E + IS T + DQ + S V T P
Sbjct: 32793 ISGEGGTSKTNLQFMGQAFKSIHEKVSKISETKK--SDQKTTESTVTRKTEPKAPEPISS 32850
Query: 124 ---LLSGNDFQTVEEGSNVKLVCNVKANPQAQMMWYKNSSLLDLEKSRHQIQQTSESFQL 180
+++G TV S K P+ +W K+ + + ++++ + F L
Sbjct: 32851 KPVIVTGLQDTTVSSDSVAKFAVKATGEPRPTAIWTKDGKAIT-QGGKYKLSEDKGGFFL 32909
Query: 181 SITKVEKPDNGTYSCIAKSSLKTESLDFHLIVK 213
I K + D+G Y+C K+S + S L +K
Sbjct: 32910 EIHKTDTSDSGLYTCTVKNSAGSVSSSCKLTIK 32942
Score = 42.0 bits (97), Expect = 5e-04
Identities = 21/70 (30%), Positives = 38/70 (54%), Gaps = 1/70 (1%)
Query: 132 TVEEGSNVKLVCNVKANPQAQMMWYKNSSLLDLEKS-RHQIQQTSESFQLSITKVEKPDN 190
TV+ G ++L V+ P ++ W K+ DL +S R +I ++S + S+TK ++ D
Sbjct: 18212 TVKAGDTIRLEAGVRGKPFPEVAWTKDKDATDLTRSPRVKIDTRADSSKFSLTKAKRSDG 18271
Query: 191 GTYSCIAKSS 200
G Y A ++
Sbjct: 18272 GKYVVTATNT 18281
Score = 41.6 bits (96), Expect = 7e-04
Identities = 21/82 (25%), Positives = 41/82 (50%), Gaps = 1/82 (1%)
Query: 136 GSNVKLVCNVKANPQAQMMWYKNSSLLDLEKSRHQIQQTSESFQLSITKVEKPDNGTYSC 195
G + C+V ++ W K+S + ++QI S L++ KV+K D+G Y+C
Sbjct: 8167 GESADFECHVTGTQPIKVSWAKDSREIR-SGGKYQISYLENSAHLTVLKVDKGDSGQYTC 8225
Query: 196 IAKSSLKTESLDFHLIVKDKTV 217
A + + +S L +K++ +
Sbjct: 8226 YAVNEVGKDSCTAQLNIKERLI 8247
Score = 41.2 bits (95), Expect = 0.001
Identities = 39/189 (20%), Positives = 78/189 (41%), Gaps = 12/189 (6%)
Query: 46 PGSQASLICAVQNHTREEELLWYREEGRVDLKSGNK---INSSSVC-VSSISENDNGISF 101
PG A L C ++ + ++ W++ + + + +NS ++ ++ + D+G S+
Sbjct: 3751 PGESARLHCKLKG-SPVIQVTWFKNNKELSESNTVRMYFVNSEAILDITDVKVEDSG-SY 3808
Query: 102 TCRLGRD---QSVSVSVVLNVTFPPLLSGNDFQTVEEGSNVKLVCNVKANPQAQMMWYKN 158
+C D S S +V+ P + + + G+N L C V ++ W+K+
Sbjct: 3809 SCEAVNDVGSDSCSTEIVIKEP-PSFIKTLEPADIVRGTNALLQCEVSGTGPFEISWFKD 3867
Query: 159 SSLLDLEKSRHQIQQTSESFQLSITKVEKPDNGTYSCIAKSSL-KTESLDFHLIVKDKTV 217
+ K Q S L I D G Y C+ + + K + HL+ + T
Sbjct: 3868 KKQIRSSKKYRLFSQKS-LVCLEIFSFNSADVGEYECVVANEVGKCGCMATHLLKEPPTF 3926
Query: 218 GVPIEPIIA 226
++ +IA
Sbjct: 3927 VKKVDDLIA 3935
Score = 41.2 bits (95), Expect = 0.001
Identities = 22/88 (25%), Positives = 46/88 (52%), Gaps = 5/88 (5%)
Query: 133 VEEGSNVKLVCNVKANPQAQMMWYKNSSLLD-----LEKSRHQIQQTSESFQLSITKVEK 187
V+ G V + +V P ++ W KN ++++ L+ ++ ++ ++ +LSI K +
Sbjct: 15410 VKAGEPVHIPADVTGLPMPKIEWSKNETVIEKPTDALQITKEEVSRSEAKTELSIPKAVR 15469
Query: 188 PDNGTYSCIAKSSLKTESLDFHLIVKDK 215
D GTY+ A + L + + H+ V D+
Sbjct: 15470 EDKGTYTVTASNRLGSVFRNVHVEVYDR 15497
Score = 41.2 bits (95), Expect = 0.001
Identities = 23/73 (31%), Positives = 36/73 (49%), Gaps = 2/73 (2%)
Query: 136 GSNVKLVCNVKANPQAQMMWYKNSSLLDLEKSRHQIQQTSESFQLSITKVEKPDNGTYSC 195
G N + + NV++ P A++ WY N L E S+ TS L I D+GTY
Sbjct: 32388 GQNTRFILNVQSKPTAEVKWYHNGVELQ-ESSKIHYTNTSGVLTLEILDCHTDDSGTYRA 32446
Query: 196 IAKSSLKTESLDF 208
+ ++ K E+ D+
Sbjct: 32447 VC-TNYKGEASDY 32458
Score = 40.8 bits (94), Expect = 0.001
Identities = 43/178 (24%), Positives = 77/178 (43%), Gaps = 14/178 (7%)
Query: 47 GSQASLICAVQNHTREEELLWYREEGRVDLKSGNKI----NSSSVCVSSISENDNGISFT 102
G ASL C + T E + WY+ + ++ + K+ N +++ + + ND+G +
Sbjct: 7975 GDSASLQCQLAG-TPEIGVSWYKGDTKLRPTTTYKMHFRNNVATLVFNQVDINDSG-EYI 8032
Query: 103 CRLGRDQS-VSVSVVLNVT---FPPLLSGNDFQTVEEGSNVKLV--CNVKANPQAQMMWY 156
C+ VS S L V PP S + V+E + +V C + + + WY
Sbjct: 8033 CKAENSVGEVSASTFLTVQEQKLPPSFS-RQLRDVQETVGLPVVFDCAISGSEPISVSWY 8091
Query: 157 KNSSLLDLEKSRHQIQQTSESFQLSITKVEKPDNGTYSCIAKSSLKTESLDFHLIVKD 214
K+ L + Q + L+I K ++ G YSC A + + + S LI+ +
Sbjct: 8092 KDGKPLK-DSPNVQTSFLDNTATLNIFKTDRSLAGQYSCTATNPIGSASSSARLILTE 8148
Score = 40.4 bits (93), Expect = 0.002
Identities = 42/169 (24%), Positives = 75/169 (44%), Gaps = 17/169 (10%)
Query: 47 GSQASLICAVQNHTREEELLWYREEGRVDLKSGNKINSS---SVCVSSISE---NDNGIS 100
G L C + + E ++ W+R + +L K N S SV + +I+E D+G
Sbjct: 6379 GESIQLECKISG-SPEIKVSWFRNDS--ELHESWKYNMSFINSVALLTINEASAEDSG-D 6434
Query: 101 FTCRLGRDQS-VSVSVVLNVTFPPLLSGNDFQT-VEEGSNVKLVCNVKANPQAQMMWYKN 158
+ C S S L V PP+ + +GS+V L C + P +++W K+
Sbjct: 6435 YICEAHNGVGDASCSTALTVKAPPVFTQKPSPVGALKGSDVILQCEISGTPPFEVVWVKD 6494
Query: 159 SSLLDLEKSRHQIQQTSESF--QLSITKVEKPDNGTYSCIAKSSLKTES 205
+ ++ + + TS+ F L I +E D G Y C A + + +++
Sbjct: 6495 RKQV---RNSKKFKITSKHFDTSLHILNLEASDVGEYHCKATNEVGSDT 6540
Score = 40.0 bits (92), Expect = 0.002
Identities = 33/133 (24%), Positives = 58/133 (43%), Gaps = 4/133 (3%)
Query: 89 VSSISENDNGISFTCRLGRDQSVSVSVVLNVTFPP-LLSGNDFQTVEEGSNVKLVCNVKA 147
+S ++D G +T GR++S SV++ +N PP +L TV+ G + +
Sbjct: 3207 ISETRQSDAG-EYTFVAGRNRS-SVTLYVNAPEPPQVLQELQPVTVQSGKPARFCAVISG 3264
Query: 148 NPQAQMMWYKNSSLLDLEKSRHQIQQTSESFQLSITKVEKPDNGTYSCIAKSSLKTESLD 207
PQ ++ WYK LL + + + + L + + D Y+C AK+ +
Sbjct: 3265 RPQPKISWYKEEQLLS-TGFKCKFLHDGQEYTLLLIEAFPEDAAVYTCEAKNDYGVATTS 3323
Query: 208 FHLIVKDKTVGVP 220
L V+ V P
Sbjct: 3324 ASLSVEVPEVVSP 3336
Score = 39.3 bits (90), Expect = 0.004
Identities = 40/169 (23%), Positives = 75/169 (44%), Gaps = 18/169 (10%)
Query: 42 LDTTPGSQASLICAVQNHTREEELLWYREEGRVDLKSGNKINS------SSVCVSSISEN 95
++T G+ L C +Q T + WY+++ +L+SG K +S+ + ++
Sbjct: 7408 IETLKGADVHLECELQG-TPPFHVSWYKDKR--ELRSGKKYKIMSENFLTSIHILNVDAA 7464
Query: 96 DNGISFTCR----LGRDQSV-SVSVVLNVTFPPLLSGNDFQTVEEGSNVKLVCNVKANPQ 150
D G + C+ +G D V S+++ F LS D TV G V+L ++
Sbjct: 7465 DIG-EYQCKATNDVGSDTCVGSIALKAPPRFVKKLS--DISTVV-GKEVQLQTTIEGAEP 7520
Query: 151 AQMMWYKNSSLLDLEKSRHQIQQTSESFQLSITKVEKPDNGTYSCIAKS 199
++W+K+ + E I + L ++VE + G Y+C K+
Sbjct: 7521 ISVVWFKDKGEIVRESDNIWISYSENIATLQFSRVEPANAGKYTCQIKN 7569
Score = 38.5 bits (88), Expect = 0.006
Identities = 44/206 (21%), Positives = 82/206 (39%), Gaps = 35/206 (16%)
Query: 24 REMTSSVLTVNGKTENYILD-----TTPGSQASLICAVQNHTREEELLWYREEGRVD--- 75
R +S L VN +L T + + CAV + + ++ WY+EE +
Sbjct: 3224 RNRSSVTLYVNAPEPPQVLQELQPVTVQSGKPARFCAVISGRPQPKISWYKEEQLLSTGF 3283
Query: 76 ----LKSGNKINSSSVCVSSISENDNGISFTCRLGRDQSVSV-SVVLNVTFPPLLSGNDF 130
L G + + + + + E+ +TC D V+ S L+V P ++S +
Sbjct: 3284 KCKFLHDGQEY--TLLLIEAFPED--AAVYTCEAKNDYGVATTSASLSVEVPEVVSPDQE 3339
Query: 131 QTV--------------EEGSNVKLVCNVKANPQAQMMWYKNSSLLDLEKSRH-QIQQTS 175
V EG + C V ++ WY ++ SR ++ Q
Sbjct: 3340 MPVYPPAIITPLQDTVTSEGQPARFQCRVSGT-DLKVSWYSKDK--KIKPSRFFRMTQFE 3396
Query: 176 ESFQLSITKVEKPDNGTYSCIAKSSL 201
+++QL I + D GTY+ +A +++
Sbjct: 3397 DTYQLEIAEAYPEDEGTYTFVASNAV 3422
Score = 38.5 bits (88), Expect = 0.006
Identities = 24/112 (21%), Positives = 51/112 (45%), Gaps = 10/112 (8%)
Query: 93 SENDNGISFTCRLGRDQSVSVSVVLNVTF---PPLLSGNDFQTVEEGSNVKLVCNVKANP 149
+EN+ G+S R + ++S+ +T P + T + G +L C + P
Sbjct: 30507 AENETGLS------RPRRTAMSIKTKLTSGEAPGIRKEMKDVTTKLGEAAQLSCQIVGRP 30560
Query: 150 QAQMMWYKNSSLLDLEKSRHQIQQTSESFQLSITKVEKPDNGTYSCIAKSSL 201
+ WY+ L ++ ++++ + L++ E+ D G Y+CIA + +
Sbjct: 30561 LPDIKWYRFGKEL-IQSRKYKMSSDGRTHTLTVMTEEQEDEGVYTCIATNEV 30611
Score = 37.7 bits (86), Expect = 0.010
Identities = 37/160 (23%), Positives = 74/160 (46%), Gaps = 11/160 (6%)
Query: 64 ELLWYREEGRVDLKS--GNKINSSS----VCVSSISENDNG---ISFTCRLGRDQSVSVS 114
E+ W+R+ + + G +I+ S + + ++++ ++G + T G+ S +
Sbjct: 36 EVSWFRDGQVISTSTLPGVQISFSDGRAKLTIPAVTKANSGRYSLKATNGSGQATSTAEL 95
Query: 115 VVLNVTFPP-LLSGNDFQTVEEGSNVKLVCNVKANPQAQMMWYKNSSLLDLEKSRHQIQQ 173
+V T PP + TV +GS V+L V P + +Y++ + + QI Q
Sbjct: 96 LVKAETAPPNFVQRLQSMTVRQGSQVRLQVRVTGIPTPVVKFYRDGAEIQSSLD-FQISQ 154
Query: 174 TSESFQLSITKVEKPDNGTYSCIAKSSLKTESLDFHLIVK 213
+ + L I + D+GTYS A +S+ + L+V+
Sbjct: 155 EGDLYSLLIAEAYPEDSGTYSVNATNSVGRATSTAELLVQ 194
Score = 37.7 bits (86), Expect = 0.010
Identities = 41/180 (22%), Positives = 66/180 (36%), Gaps = 15/180 (8%)
Query: 48 SQASLICAVQNHTREEELLWYREEGRVDLKSGNKINSSS-------VCVSSISENDNGIS 100
S A+L+C V H + + WYR+ G+ + G K + ++S++++D +
Sbjct: 30943 SNATLVCKVTGHPKPI-VKWYRQ-GKEIIADGLKYRIQEFKGGYHQLIIASVTDDDATVY 31000
Query: 101 FTCRLGRDQSVS------VSVVLNVTFPPLLSGNDFQTVEEGSNVKLVCNVKANPQAQMM 154
+ SVS V V + P L G G V + P +
Sbjct: 31001 QVRATNQGGSVSGTASLEVEVPAKIHLPKTLEGMGAVHALRGEVVSIKIPFSGKPDPVIT 31060
Query: 155 WYKNSSLLDLEKSRHQIQQTSESFQLSITKVEKPDNGTYSCIAKSSLKTESLDFHLIVKD 214
W K L+D I S + + VE+ D G Y AK+ + L V D
Sbjct: 31061 WQKGQDLIDNNGHYQVIVTRSFTSLVFPNGVERKDAGFYVVCAKNRFGIDQKTVELDVAD 31120
Score = 37.4 bits (85), Expect = 0.013
Identities = 23/68 (33%), Positives = 36/68 (52%), Gaps = 2/68 (2%)
Query: 131 QTVEEGSNVKLVCNVKANPQAQMMWYKNSSLLDLEKSRHQIQQTSESFQLSITKVEKPDN 190
QTVEEG+ L C V + A++ W+KN + + L+ +++I +L I D
Sbjct: 12294 QTVEEGATAVLECEV-SRENAKVKWFKNGTEI-LKSKKYEIVADGRVRKLVIHDCTPEDI 12351
Query: 191 GTYSCIAK 198
TY+C AK
Sbjct: 12352 KTYTCDAK 12359
Score = 37.0 bits (84), Expect = 0.017
Identities = 30/107 (28%), Positives = 49/107 (45%), Gaps = 7/107 (6%)
Query: 109 QSVSVSVVLNVTFPPLLSGNDFQTVEEGSNVKLVCNVKANPQAQMMWYKNSSLLDLEKSR 168
++V + L+V LL TV+ G+NV L V P + W K+ +LL +
Sbjct: 19289 ENVPPRIDLSVAMKSLL------TVKAGTNVCLDATVFGKPMPTVSWKKDGTLLKPAEGI 19342
Query: 169 HQIQQTSESFQLSITKVEKPDNGTYSCIAKSSLKTESLDFHLIVKDK 215
Q + L + V + D+G Y+ A++S ++S L V DK
Sbjct: 19343 KMAMQRN-LCTLELFSVNRKDSGDYTITAENSSGSKSATIKLKVLDK 19388
Score = 37.0 bits (84), Expect = 0.017
Identities = 31/106 (29%), Positives = 49/106 (46%), Gaps = 4/106 (3%)
Query: 110 SVSVSVVLNVTFPPLLSGNDFQTV-EEGSNVKLVCNVKANPQA-QMMWYKNSSLLDLEKS 167
SV+ V ++ P+ SG V EEG +VK VC ++ Q+ Q+ WY L+
Sbjct: 31556 SVAKVKVASIEIGPV-SGQIMHAVGEEGGHVKYVCKIENYDQSTQVTWYFGVRQLE-NSE 31613
Query: 168 RHQIQQTSESFQLSITKVEKPDNGTYSCIAKSSLKTESLDFHLIVK 213
+++I L + + K D+GTY C + +S L VK
Sbjct: 31614 KYEITYEDGVAILYVKDITKLDDGTYRCKVVNDYGEDSSYAELFVK 31659
Score = 37.0 bits (84), Expect = 0.017
Identities = 39/203 (19%), Positives = 80/203 (39%), Gaps = 39/203 (19%)
Query: 47 GSQASLICAVQNHTREEELLWYREEGRVDLKSGNKINSSS----VCVSSISENDNGISFT 102
G +C ++N+ + ++ WY +++ +I + V I++ D+G ++
Sbjct: 31582 GGHVKYVCKIENYDQSTQVTWYFGVRQLENSEKYEITYEDGVAILYVKDITKLDDG-TYR 31640
Query: 103 CRL----GRDQSVSVSVVLNV--------------------TFPPLLSGNDF------QT 132
C++ G D S + V V T L +F +T
Sbjct: 31641 CKVVNDYGEDSSYAELFVKGVREVYDYYCRRTMKKIKRRTDTMRLLERPPEFTLPLYNKT 31700
Query: 133 VEEGSNVKLVCNVKANPQAQMMWYKNSSLL---DLEKSRHQIQQTSESFQLSITKVEKPD 189
G NV+ + +P+ + WYK+ + D +K ++ + +QL+I V D
Sbjct: 31701 AYVGENVRFGVTITVHPEPHVTWYKSGQKIKPGDNDK-KYTFESDKGLYQLTINSVTTDD 31759
Query: 190 NGTYSCIAKSSLKTESLDFHLIV 212
+ Y+ +A++ +S L V
Sbjct: 31760 DAEYTVVARNKYGEDSCKAKLTV 31782
Score = 36.6 bits (83), Expect = 0.023
Identities = 35/165 (21%), Positives = 69/165 (41%), Gaps = 8/165 (4%)
Query: 41 ILDTTPGSQASLICAVQNHTREEELLWYREEGRVDLKSGNKINS----SSVCVSSISEND 96
I++T ++ SL C + T E++WY+++ ++ KI S +S+ + ++ +D
Sbjct: 5525 IVETLKNAEVSLECELSG-TPPFEVVWYKDKRQLRSSKKYKIASKNFHTSIHILNVDTSD 5583
Query: 97 NGISFTCRLGRDQSVSVSV-VLNVTFPP-LLSGNDFQTVEEGSNVKLVCNVKANPQAQMM 154
G + C+ + V + + PP +S + TV G +L +++ +
Sbjct: 5584 IG-EYHCKAQNEVGSDTCVCTVKLKEPPRFVSKLNSLTVVAGEPAELQASIEGAQPIFVQ 5642
Query: 155 WYKNSSLLDLEKSRHQIQQTSESFQLSITKVEKPDNGTYSCIAKS 199
W K + E +I L K E + G Y C K+
Sbjct: 5643 WLKEKEEVIRESENIRITFVENVATLQFAKAEPANAGKYICQIKN 5687
Score = 36.6 bits (83), Expect = 0.023
Identities = 40/176 (22%), Positives = 75/176 (42%), Gaps = 13/176 (7%)
Query: 47 GSQASLICAVQNHTREEELLWYREEGRVDLKSGNKIN---SSSVC---VSSISENDNGIS 100
G+ L C V + + W+ E+ ++ SG K S +VC ++S+ +D G +
Sbjct: 5814 GASCILECKVAGSS-PISVAWFHEKTKI--VSGAKYQTTFSDNVCTLQLNSLDSSDMG-N 5869
Query: 101 FTCRLGRDQ-SVSVSVVLNVTFPP-LLSGNDFQTVEEGSNVKLVCNVKANPQAQMMWYKN 158
+TC S VL V PP + + V G NV ++ P ++ W++
Sbjct: 5870 YTCVAANVAGSDECRAVLTVQEPPSFVKEPEPLEVLPGKNVTFTSVIRGTPPFKVNWFRG 5929
Query: 159 SSLLDLEKSRHQIQQTSESFQLSITKVEKPDNGTYSCIAKSSLKTESLDFHLIVKD 214
+ L ++ R I +L + ++ +G Y+C+ ++ S L VK+
Sbjct: 5930 AREL-VKGDRCNIYFEDTVAELELFNIDISQSGEYTCVVSNNAGQASCTTRLFVKE 5984
Score = 36.6 bits (83), Expect = 0.023
Identities = 42/212 (19%), Positives = 84/212 (39%), Gaps = 21/212 (9%)
Query: 23 PREMTSSVLTVNGKTENYILDTT--PGSQASLICAVQNHTREEELLWYRE------EGRV 74
P ++ + + E ++ D T G ++ C + E W+R +GR
Sbjct: 8733 PHIASAKLTVIEPAWERHLQDVTLKEGQTCTMTCQFSVPNVKSE--WFRNGRILKPQGRH 8790
Query: 75 DLKSGNKINSSSVCVSSISENDNGISFTCRLGRDQSVSVSVVLNVTFPPLLSGNDFQT-- 132
+ +K++ + ++ + D G +TC+ + + S L + P+ Q
Sbjct: 8791 KTEVEHKVHK--LTIADVRAEDQG-QYTCKY---EDLETSAELRIEAEPIQFTKRIQNIV 8844
Query: 133 VEEGSNVKLVCNVKANPQAQMMWYKNSSLLDLEKSRHQIQQTSESFQLSITKVEKPDNGT 192
V E + C V + A + WYK + L E ++ + ++I V D G
Sbjct: 8845 VSEHQSATFECEVSFD-DAIVTWYKGPTELT-ESQKYNFRNDGRCHYMTIHNVTPDDEGV 8902
Query: 193 YSCIAKSSLKTESLD-FHLIVKDKTVGVPIEP 223
YS IA+ + E+ L + K + + ++P
Sbjct: 8903 YSVIARLEPRGEARSTAELYLTTKEIKLELKP 8934
Score = 36.6 bits (83), Expect = 0.023
Identities = 23/83 (27%), Positives = 38/83 (45%), Gaps = 1/83 (1%)
Query: 133 VEEGSNVKLVCNVKANPQAQMMWYKNSSLLDLEKSRHQIQQTSESFQLSITKVEKPDNGT 192
V+ +K+ K PQA + W K+ L E +R + + LSI + K D GT
Sbjct: 25406 VKAREQLKIDVPFKGRPQATVNWRKDGQTLK-ETTRVNVSSSKTVTSLSIKEASKEDVGT 25464
Query: 193 YSCIAKSSLKTESLDFHLIVKDK 215
Y +S + ++ +IV D+
Sbjct: 25465 YELCVSNSAGSITVPITIIVLDR 25487
Score = 35.8 bits (81), Expect = 0.039
Identities = 22/86 (25%), Positives = 42/86 (48%), Gaps = 1/86 (1%)
Query: 129 DFQTVEEGSNVKLVCNVKANPQAQMMWYKNSSLLDLEKSRHQIQQTSESFQLSITKVEKP 188
D T+ GS++ L V P+ +++W K LDL + +Q T + I ++
Sbjct: 29055 DLVTIRAGSDLVLDAAVGGKPEPKIIWTKGDKELDL-CEKVSLQYTGKRATAVIKFCDRS 29113
Query: 189 DNGTYSCIAKSSLKTESLDFHLIVKD 214
D+G Y+ K++ T+++ + V D
Sbjct: 29114 DSGKYTLTVKNASGTKAVSVMVKVLD 29139
Score = 35.0 bits (79), Expect = 0.066
Identities = 30/146 (20%), Positives = 59/146 (40%), Gaps = 12/146 (8%)
Query: 64 ELLWYREEGRVDLKSGNKI-----NSSSVCVSSISENDNGISFTCRLGRDQSVSVSVVLN 118
E W+ + ++ +K+ + S+ + + +D+G R S+SV+L
Sbjct: 1487 ETFWFHDGQQIVNDYTHKVVIKEDGTQSLIIVPATPSDSGEWTVVAQNRAGRSSISVILT 1546
Query: 119 VTF------PPLLSGNDFQTVEEGSNVKLVCNVKANPQAQMMWYKNSSLLDLEK-SRHQI 171
V P + ++EGS +++ NP ++W KNS ++ K + +I
Sbjct: 1547 VEAVEHQVKPMFVEKLKNVNIKEGSRLEMKVRATGNPNPDIVWLKNSDIIVPHKYPKIRI 1606
Query: 172 QQTSESFQLSITKVEKPDNGTYSCIA 197
+ T L I D+ Y+ A
Sbjct: 1607 EGTKGEAALKIDSTVSQDSAWYTATA 1632
Score = 34.3 bits (77), Expect = 0.11
Identities = 28/112 (25%), Positives = 50/112 (44%), Gaps = 6/112 (5%)
Query: 122 PPLLSGN----DFQTVEEGSNVKLVCNVKANPQAQMMWYKNSSLLDLEKSRHQIQQTSES 177
PP +S + D V G + K+ ++ P + W K L +R +I+ T +
Sbjct: 22540 PPRISMDPKYKDTIVVHAGESFKVDADIYGKPIPTIQWIKGDQELS-NTARLEIKSTDFA 22598
Query: 178 FQLSITKVEKPDNGTYSCIAKSSLKTESLDFHLIVKDKTVGVPIEPIIAACV 229
LS+ + D+G Y AK+ S+ ++ V D+ G P P++ + V
Sbjct: 22599 TSLSVKDAVRVDSGNYILKAKNVAGERSVTVNVKVLDRP-GPPEGPVVISGV 22649
Score = 33.9 bits (76), Expect = 0.15
Identities = 37/179 (20%), Positives = 70/179 (39%), Gaps = 9/179 (5%)
Query: 42 LDTTPGSQASLICAVQNHTREEELLWYREEGRVDLKSGNKI----NSSSVCVSSISENDN 97
L T G A IC V T E +W ++ + +I N + +S+++ D
Sbjct: 3560 LTTFVGKAAKFICTVTG-TPVIETIWQKDGAALSPSPNWRISDAENKHILELSNLTIQDR 3618
Query: 98 GISFTCRLGRDQSVSVSVVLNVTFPPLLSGNDFQTVEEGSNVK--LVCNVKANPQAQMMW 155
G+ ++C+ + + + + V+ N K L C V + + + W
Sbjct: 3619 GV-YSCKASNKFGADICQAELIIIDKPHFIKELEPVQSAINKKVHLECQVDEDRKVTVTW 3677
Query: 156 YKNSSLLDLEKSRHQIQQTSESFQLSITKVEKPDNGTYSCIAKSSLKTESLDFHLIVKD 214
K+ L K ++I + L I + D+GTY C A + + S + V++
Sbjct: 3678 SKDGQKLPPGKD-YKICFEDKIATLEIPLAKLKDSGTYVCTASNEAGSSSCSATVTVRE 3735
Score = 33.9 bits (76), Expect = 0.15
Identities = 40/184 (21%), Positives = 80/184 (43%), Gaps = 14/184 (7%)
Query: 41 ILDTTPGSQASLICAVQNHTREEELLWYREEGRVDLKSGN-----KINSSSVCVSSISEN 95
++ T G A+L V T E + WY++ GR + S K N + + S +
Sbjct: 4025 LIQVTAGDPATLEYTVAG-TPELKPKWYKD-GRPLVASKKYRISFKNNVAQLKFYSAELH 4082
Query: 96 DNG---ISFTCRLGRDQSVSVSVVLNVTFPPLLSG--NDFQTVEEGSNVKLVCNVKANPQ 150
D+G + +G + VL+ P + + +V G+ +L C + +
Sbjct: 4083 DSGQYTFEISNEVGSSSCETTFTVLDRDIAPFFTKPLRNVDSVVNGT-CRLDCKIAGSLP 4141
Query: 151 AQMMWYKNSSLLDLEKSRHQIQQTSESFQLSITKVEKPDNGTYSCIAKSSLKTESLDFHL 210
++ W+K+ + R++I + L I +V+ D G ++C A +S+ ++ L
Sbjct: 4142 MRVSWFKDGKEI-AASDRYRIAFVEGTASLEIIRVDMNDAGNFTCRATNSVGSKDSSGAL 4200
Query: 211 IVKD 214
IV++
Sbjct: 4201 IVQE 4204
Score = 33.9 bits (76), Expect = 0.15
Identities = 20/83 (24%), Positives = 39/83 (46%), Gaps = 1/83 (1%)
Query: 133 VEEGSNVKLVCNVKANPQAQMMWYKNSSLLDLEKSRHQIQQTSESFQLSITKVEKPDNGT 192
V G + L C + P+ + WYK + L + +++ + L +V+ D+G
Sbjct: 7972 VSVGDSASLQCQLAGTPEIGVSWYKGDTKL-RPTTTYKMHFRNNVATLVFNQVDINDSGE 8030
Query: 193 YSCIAKSSLKTESLDFHLIVKDK 215
Y C A++S+ S L V+++
Sbjct: 8031 YICKAENSVGEVSASTFLTVQEQ 8053
Score = 33.9 bits (76), Expect = 0.15
Identities = 44/218 (20%), Positives = 84/218 (38%), Gaps = 30/218 (13%)
Query: 28 SSVLTVNGKTE--NYILDTTPGSQASLICAVQNHTREEELLWYREEGRVDLKSGNKIN-- 83
+ +L + TE ++ D T + + Q + + WYR GR ++K G K
Sbjct: 12814 AELLIIEAPTEFVEHLEDQTVTEFDDAVFSCQLSREKANVKWYRN-GR-EIKEGKKYKFE 12871
Query: 84 ---SSSVCVSSISENDNGISFTC----RLGRDQSVSVSVVLNVTFPPLLSGNDFQTVEEG 136
S + D+ + C R R + + + + PP Q + E
Sbjct: 12872 KDGSIHRLIIKDCRLDDECEYACGVEDRKSRARLFVEEIPVEIIRPP-------QDILEA 12924
Query: 137 SNVKLVCNVKANP-QAQMMWYKNSSLLDLEKSRHQIQQTSESFQLSITKVEKPDNGTYSC 195
+V + N + ++ W +N+ ++ ++ +HQ+ + +L I ++ D G Y
Sbjct: 12925 PGADVVFLAELNKDKVEVQWLRNNMVV-VQGDKHQMMSEGKIHRLQICDIKPRDQGEYRF 12983
Query: 196 IAKSSLKTESLDFHLIVKDKT--------VGVPIEPII 225
IAK L+ K KT VG P+ ++
Sbjct: 12984 IAKDKEARAKLELAAAPKIKTADQDLVVDVGKPLTMVV 13021
Score = 33.9 bits (76), Expect = 0.15
Identities = 26/93 (27%), Positives = 43/93 (46%), Gaps = 7/93 (7%)
Query: 132 TVEEGSNVKLVCNVKANPQAQMMWYKNSSLLDLEKSRH-QIQQTSESFQLSITKVEKPDN 190
TV G NV L K P+ + W K+ L L++S + +T LSI +K
Sbjct: 27574 TVRIGHNVHLELPYKGKPKPSISWLKDG--LPLKESEFVRFSKTENKITLSIKNAKKEHG 27631
Query: 191 GTYSCIAKSSLKTESLDFHLIVKDKTVGVPIEP 223
G Y+ I +++ ++ +I T+G P +P
Sbjct: 27632 GKYTVILDNAVCRIAVPITVI----TLGPPSKP 27660
Score = 33.1 bits (74), Expect = 0.25
Identities = 34/157 (21%), Positives = 63/157 (40%), Gaps = 17/157 (10%)
Query: 50 ASLICAVQNHTREEELLWYREEGRV------DLKSGNKINSSSVCVSSISENDNG-ISFT 102
A ++ + + + E+ W R V + S KI+ +C I D G F
Sbjct: 12927 ADVVFLAELNKDKVEVQWLRNNMVVVQGDKHQMMSEGKIHRLQIC--DIKPRDQGEYRF- 12983
Query: 103 CRLGRDQSVSVSVVLNVTFPPLLSGNDFQTVEEGSNVKLVCNVKANPQAQMMWYKNSSLL 162
+ +D+ + L P + + + V+ G + +V A P+A+ W+K + L
Sbjct: 12984 --IAKDKEARAKLELAAA-PKIKTADQDLVVDVGKPLTMVVPYDAYPKAEAEWFKENEPL 13040
Query: 163 DLEKSRHQIQQTSESFQLSITKVEKPDNGTYSCIAKS 199
S I T+E I + +K D G Y + ++
Sbjct: 13041 ----STKTIDTTAEQTSFRILEAKKGDKGRYKIVLQN 13073
Score = 32.7 bits (73), Expect = 0.33
Identities = 36/177 (20%), Positives = 74/177 (41%), Gaps = 7/177 (3%)
Query: 43 DTTPGSQASLICAVQNHTREEELLWYREEGRVDLKSGNKINS--SSVCVSSISENDNGIS 100
D G+ A L C V T E+ W++++ ++ ++ S S VC+ S N +
Sbjct: 3841 DIVRGTNALLQCEVSG-TGPFEISWFKDKKQIRSSKKYRLFSQKSLVCLEIFSFNSADVG 3899
Query: 101 -FTCRLGRDQSVSVSVVLNVTFPP--LLSGNDFQTVEEGSNVKLVCNVKANPQAQMMWYK 157
+ C + + + ++ P + D G V L V+ + + W K
Sbjct: 3900 EYECVVANEVGKCGCMATHLLKEPPTFVKKVDDLIALGGQTVTLQAAVRGSEPISVTWMK 3959
Query: 158 NSSLLDLEKSRHQIQQTSESFQLSITKVEKPDNGTYSCIAKSSLKTESLDFHLIVKD 214
++ E + ++ ++ L I V+ G Y+C+A++ +++ LIVK+
Sbjct: 3960 GQEVIR-EDGKIKMSFSNGVAVLIIPDVQISFGGKYTCLAENEAGSQTSVGELIVKE 4015
Score = 32.7 bits (73), Expect = 0.33
Identities = 35/182 (19%), Positives = 75/182 (41%), Gaps = 12/182 (6%)
Query: 42 LDTTPGSQASLICAVQNHTREEELLWYREEGRVD----LKSGNKINSSSVCVSSISENDN 97
+D T +L C V T E ++ W ++ ++ + N +S + S+ + D+
Sbjct: 5150 VDVTEKDPMTLECVVAG-TPELKVKWLKDGKQIVPSRYFSMSFENNVASFRIQSVMKQDS 5208
Query: 98 GISFTCRLGRDQSVSVSV----VLNVTFPPLLSGNDFQTVEE-GSNVKLVCNVKANPQAQ 152
G +T ++ D S VL+ PP + + + GS++ + C V +
Sbjct: 5209 G-QYTFKVENDFGSSSCDAYLRVLDQNIPPSFTKKLTKMDKVLGSSIHMECKVSGSLPIS 5267
Query: 153 MMWYKNSSLLDLEKSRHQIQQTSESFQLSITKVEKPDNGTYSCIAKSSLKTESLDFHLIV 212
W+K+ + +++++ S L + +E D Y+C + ++ L V
Sbjct: 5268 AQWFKDGKEIS-TSAKYRLVCHERSVSLEVNNLELEDTANYTCKVSNVAGDDACSGILTV 5326
Query: 213 KD 214
K+
Sbjct: 5327 KE 5328
Score = 32.0 bits (71), Expect = 0.56
Identities = 41/183 (22%), Positives = 73/183 (39%), Gaps = 14/183 (7%)
Query: 42 LDTTPGSQASLICAVQNHTREEELLWYREEGRVDLKSGNKINSS---SVCVSSISENDNG 98
++ T G +L C + N + ++ WYR+ V L+ + +S +V I + D
Sbjct: 6184 IEQTVGLPVTLTCRL-NGSAPIQVCWYRDG--VLLRDDENLQTSFVDNVATLKILQTDLS 6240
Query: 99 IS--FTCRLGRDQ-SVSVSVVLNVTFPPLLSGNDFQTVE----EGSNVKLVCNVKANPQA 151
S ++C + S S L P D + V G + C+V
Sbjct: 6241 HSGQYSCSASNPLGTASSSARLTAREPKKSPFFDIKPVSIDVIAGESADFECHVTGAQPM 6300
Query: 152 QMMWYKNSSLLDLEKSRHQIQQTSESFQLSITKVEKPDNGTYSCIAKSSLKTESLDFHLI 211
++ W K++ + + I + L I KV K D+G Y+C A + + + L
Sbjct: 6301 RITWSKDNKEIR-PGGNYTITCVGNTPHLRILKVGKGDSGQYTCQATNDVGKDMCSAQLS 6359
Query: 212 VKD 214
VK+
Sbjct: 6360 VKE 6362
Score = 32.0 bits (71), Expect = 0.56
Identities = 22/109 (20%), Positives = 48/109 (44%), Gaps = 3/109 (2%)
Query: 109 QSVSVSVVLN--VTFPPLLSGNDFQTVEEGSNVKLVCNVKANPQAQMMWYKNSSLLDLEK 166
+S++V +V V P + +V+ G ++K+ + P+ + W K+ L +
Sbjct: 23215 RSLAVPIVAKDLVIEPDVKPAFSSYSVQVGQDLKIEVPISGRPKPTITWTKDGLPLK-QT 23273
Query: 167 SRHQIQQTSESFQLSITKVEKPDNGTYSCIAKSSLKTESLDFHLIVKDK 215
+R + + + LSI + K D G Y + + ++ ++ DK
Sbjct: 23274 TRINVTDSLDLTTLSIKETHKDDGGQYGITVANVVGQKTASIEIVTLDK 23322
Score = 32.0 bits (71), Expect = 0.56
Identities = 19/78 (24%), Positives = 39/78 (50%), Gaps = 3/78 (3%)
Query: 137 SNVKLVCNVKANPQAQMMWYKNSSLLDLEKSRHQIQQTSESFQLSITKVEKPDNGTYSCI 196
+ ++L +K P+ ++ W K +L R QI+ TS L I V + D+G Y+
Sbjct: 25123 ATLRLFVTIKGRPEPEVKWEKAEGILT---DRAQIEVTSSFTMLVIDNVTRFDSGRYNLT 25179
Query: 197 AKSSLKTESLDFHLIVKD 214
+++ +++ ++ V D
Sbjct: 25180 LENNSGSKTAFVNVRVLD 25197
Score = 32.0 bits (71), Expect = 0.56
Identities = 17/83 (20%), Positives = 37/83 (44%), Gaps = 1/83 (1%)
Query: 132 TVEEGSNVKLVCNVKANPQAQMMWYKNSSLL-DLEKSRHQIQQTSESFQLSITKVEKPDN 190
+++EG + + C P ++ W + E+ R I+ T + L I V+K D
Sbjct: 33339 SIDEGKVLTVACAFTGEPTPEVTWSCGGRKIHSQEQGRFHIENTDDLTTLIIMDVQKQDG 33398
Query: 191 GTYSCIAKSSLKTESLDFHLIVK 213
G Y+ + ++S ++ ++
Sbjct: 33399 GLYTLSLGNEFGSDSATVNIHIR 33421
Score = 31.6 bits (70), Expect = 0.73
Identities = 33/147 (22%), Positives = 62/147 (42%), Gaps = 21/147 (14%)
Query: 68 YREEGRVDLKSGN--KINSSSVCVSSISENDNGISFTCRL------GRDQSVSVSVVLNV 119
Y+EEG+ + + G ++ + + V+ + E G + R+ G + V+ V+ +
Sbjct: 16459 YKEEGKEEWEKGKDKEVRGTKLVVTGLKE---GAFYKFRVRAVNIAGIGEPGEVTDVIEM 16515
Query: 120 ----TFPPL---LSGNDFQTVEEGSNVKLVCNVKANPQAQMMWYKNSSLLDLEKSRHQIQ 172
P L S D V G ++++ V P + W N L E + I+
Sbjct: 16516 KDRLVSPDLQLDASVRDRIVVHAGGVIRIIAYVSGKPPPTVTWNMNERTLPQEAT---IE 16572
Query: 173 QTSESFQLSITKVEKPDNGTYSCIAKS 199
T+ S + I ++ G YS +AK+
Sbjct: 16573 TTAISSSMVIKNCQRSHQGVYSLLAKN 16599
Score = 31.6 bits (70), Expect = 0.73
Identities = 17/64 (26%), Positives = 31/64 (48%), Gaps = 1/64 (1%)
Query: 136 GSNVKLVCNVKANPQAQMMWYKNSSLLDLEKSRHQIQQTSESFQLSITKVEKPDNGTYSC 195
G N+K+ V P+ + W K +L + R + T+ S L+I + + D+G Y
Sbjct: 21080 GDNIKVEIPVLGRPKPTVTWKKGDQILK-QTQRVNFETTATSTILNINECVRSDSGPYPL 21138
Query: 196 IAKS 199
A++
Sbjct: 21139 TARN 21142
Score = 31.6 bits (70), Expect = 0.73
Identities = 22/96 (22%), Positives = 41/96 (42%), Gaps = 1/96 (1%)
Query: 129 DFQTVEEGSNVKLVCNVKANPQAQMMWYKNSSLLDLEKSRHQIQQTSESFQLSITKVEKP 188
D V G L +++ P ++W K+ L+ +R +I+ T + L + +
Sbjct: 24715 DVIVVHAGETFVLEADIRGKPIPDVVWSKDGKELEETAARMEIKSTIQKTTLVVKDCIRT 24774
Query: 189 DNGTYSCIAKSSLKTESLDFHLIVKDKTVGVPIEPI 224
D G Y + T+S+ + V D+ G P P+
Sbjct: 24775 DGGQYILKLSNVGGTKSIPITVKVLDRP-GPPEGPL 24809
Score = 31.2 bits (69), Expect = 0.96
Identities = 20/89 (22%), Positives = 42/89 (47%), Gaps = 3/89 (3%)
Query: 136 GSNVKLVCNVKANPQAQMMWYKNSSLLDLEKSRHQIQQTSESFQLSITKVEKPDNGTYSC 195
G++VKL + P + WYK+ L + ++ T++ + I ++ ++G Y
Sbjct: 26887 GTSVKLRAGISGKPAPTIEWYKDDKELQ-TNALVCVENTTDLASILIKDADRLNSGCYEL 26945
Query: 196 IAKSSLKTESLDFHLIVKDK--TVGVPIE 222
++++ + S + + DK G PIE
Sbjct: 26946 KLRNAMGSASATIRVQILDKPGPPGGPIE 26974
Score = 30.0 bits (66), Expect = 2.1
Identities = 31/115 (26%), Positives = 45/115 (39%), Gaps = 7/115 (6%)
Query: 84 SSSVCVSSISENDNG-ISFTC-RLGRDQSVSVSVVLNVTFPPLLSGNDFQTVEEGSNVKL 141
S + + +++ D G SFT LG S VSV PL N V EG+ L
Sbjct: 2409 SHMLLIEDMTKEDAGNYSFTIPALGLSTSGRVSVYSVDVITPLKDVN----VIEGTKAVL 2464
Query: 142 VCNVKANPQAQMMWYKNSSLLDLEKSRHQIQQTSESFQLSITKVEKPDNGTYSCI 196
C V + WY N + + I + ++ +L I + D G Y I
Sbjct: 2465 ECKVSVPDVTSVKWYLNDEQIKPDDRVQAIVKGTKQ-RLVINRTHASDEGPYKLI 2518
Score = 30.0 bits (66), Expect = 2.1
Identities = 24/108 (22%), Positives = 48/108 (44%), Gaps = 6/108 (5%)
Query: 122 PPLLSGNDFQT----VEEGSNVKLVCNVKANPQAQMMWYKNSSLLDLEKSRHQIQQTSES 177
PP + +F + V GSN+K+ + P ++ ++ L R + T+E+
Sbjct: 26473 PPEIDMKNFPSHTVYVRAGSNLKVDIPISGKPLPKVTLSRDGVPLKATM-RFNTEITAEN 26531
Query: 178 FQLSITKVEKPDNGTYSCIAKSSLKTESLDFHLIVKDKTVGVPIEPII 225
+++ + D G Y A +S T +++V D+ G P P++
Sbjct: 26532 LTINLKESVTADAGRYEITAANSSGTTKAFINIVVLDRP-GPPTGPVV 26578
Score = 29.6 bits (65), Expect = 2.8
Identities = 17/65 (26%), Positives = 26/65 (40%)
Query: 133 VEEGSNVKLVCNVKANPQAQMMWYKNSSLLDLEKSRHQIQQTSESFQLSITKVEKPDNGT 192
V E + + V +P + W K + R I Q + +L I K D+G
Sbjct: 8465 VVEKTTATFIAKVGGDPIPNVKWTKGKWRQLNQGGRVFIHQKGDEAKLEIRDTTKTDSGL 8524
Query: 193 YSCIA 197
Y C+A
Sbjct: 8525 YRCVA 8529
Score = 29.6 bits (65), Expect = 2.8
Identities = 20/80 (25%), Positives = 32/80 (40%)
Query: 134 EEGSNVKLVCNVKANPQAQMMWYKNSSLLDLEKSRHQIQQTSESFQLSITKVEKPDNGTY 193
+EG +V V P + W K+ L L + I + + + L I D G Y
Sbjct: 31807 QEGQSVCFEIRVSGIPPPTLKWEKDGQPLSLGPNIEIIHEGLDYYALHIRDTLPEDTGYY 31866
Query: 194 SCIAKSSLKTESLDFHLIVK 213
A ++ + S HL V+
Sbjct: 31867 RVTATNTAGSTSCQAHLQVE 31886
Score = 29.3 bits (64), Expect = 3.6
Identities = 20/85 (23%), Positives = 38/85 (44%), Gaps = 1/85 (1%)
Query: 133 VEEGSNVKLVCNVKANPQAQMMWYKNSSLLDLEKSRH-QIQQTSESFQLSITKVEKPDNG 191
V EGS ++ P ++ W+++ ++ QI + +L+I V K ++G
Sbjct: 17 VLEGSTATFEAHISGFPVPEVSWFRDGQVISTSTLPGVQISFSDGRAKLTIPAVTKANSG 76
Query: 192 TYSCIAKSSLKTESLDFHLIVKDKT 216
YS A + + L+VK +T
Sbjct: 77 RYSLKATNGSGQATSTAELLVKAET 101
Score = 29.3 bits (64), Expect = 3.6
Identities = 25/96 (26%), Positives = 44/96 (45%), Gaps = 13/96 (13%)
Query: 131 QTVEEGSNVKLVCNVKANPQAQMMWYKNSSLLDLEKSRHQI---QQTSESFQLSITKVEK 187
Q + EG +V C V NP+ + W K S + R+++ +QT E +L I+
Sbjct: 1091 QKLVEGGSVVFGCQVGGNPKPHVYW-KKSGVPLTTGYRYKVSYNKQTGEC-KLVISMTFA 1148
Query: 188 PDNGTYSCIAK--------SSLKTESLDFHLIVKDK 215
D G Y+ + + S+ E D+ L++K +
Sbjct: 1149 DDAGEYTIVVRNKHGETSASASLLEEADYELLMKSQ 1184
Score = 29.3 bits (64), Expect = 3.6
Identities = 21/82 (25%), Positives = 38/82 (46%), Gaps = 2/82 (2%)
Query: 136 GSNVKLVCNVKANPQAQMMWYKNSSLLDLEKSRHQIQQTSESFQLSITKVEKPDNGTYSC 195
GS+ C V + A W K+ S + E +H+ + +L I V+ D G Y+C
Sbjct: 11133 GSSAIFECLVSPST-AITTWMKDGSNIR-ESPKHRFIADGKDRKLHIIDVQLSDAGEYTC 11190
Query: 196 IAKSSLKTESLDFHLIVKDKTV 217
+ + K ++ L+V++ V
Sbjct: 11191 VLRLGNKEKTSTAKLVVEELPV 11212
Score = 28.5 bits (62), Expect = 6.2
Identities = 20/92 (21%), Positives = 41/92 (44%), Gaps = 2/92 (2%)
Query: 133 VEEGSNVKLVCNVKANPQAQMMWYKNSSLLDLEKSRHQIQQTSESFQLSITKVEKPDNGT 192
V+ G+ V+ ++ P W + S + ++ + ++ + S L+I + D G
Sbjct: 17522 VKAGTTVRFPAIIRGVPVPTAKWTTDGSEIKTDE-HYTVETDNFSSVLTIKNCLRRDTGE 17580
Query: 193 YSCIAKSSLKTESLDFHLIVKDKTVGVPIEPI 224
Y ++ ++++ HL V D G P PI
Sbjct: 17581 YQITVSNAAGSKTVAVHLTVLD-VPGPPTGPI 17611
Score = 28.1 bits (61), Expect = 8.1
Identities = 12/34 (35%), Positives = 16/34 (47%)
Query: 133 VEEGSNVKLVCNVKANPQAQMMWYKNSSLLDLEK 166
V EG + C V PQ ++ WY N L+ K
Sbjct: 1852 VLEGETARFRCRVTGYPQPKVNWYLNGQLIRKSK 1885
>gi|16506826 sialic acid binding immunoglobulin-like lectin-like
protein 1 isoform b precursor [Homo sapiens]
Length = 477
Score = 51.6 bits (122), Expect = 7e-07
Identities = 48/190 (25%), Positives = 83/190 (43%), Gaps = 35/190 (18%)
Query: 82 INSSSVCVSSISENDNGISFTCRL---GRDQSVSVSVVLNVTFPP--------------- 123
I SS+ D+G S TC++ G +++ +V LN+++PP
Sbjct: 203 ITRSSMLSLIPQPQDHGTSLTCQVTLPGAGVTMTRAVRLNISYPPQNLTMTVFQGDGTAS 262
Query: 124 -LLSGNDFQTVEEGSNVKLVCNVKANPQAQMMWYKNSSLLDLEKSRHQIQQTSESFQLSI 182
L +V EG ++ LVC V +NP A++ W S L L S Q+S L +
Sbjct: 263 TTLRNGSALSVLEGQSLHLVCAVDSNPPARLSWTWGS--LTLSPS-----QSSNLGVLEL 315
Query: 183 TKVEKPDNGTYSCIAKSSLKTESLDFHLIVKDKTVGV--PIEPI-------IAACVVIFL 233
+V D G ++C A++ L ++ + L ++++ G PI + A ++FL
Sbjct: 316 PRVHVKDEGEFTCRAQNPLGSQHISLSLSLQNEYTGKMRPISGVTLGAFGGAGATALVFL 375
Query: 234 TLCFGLIARR 243
C + R
Sbjct: 376 YFCIIFVVVR 385
>gi|16506828 sialic acid binding immunoglobulin-like lectin-like
protein 1 isoform a precursor [Homo sapiens]
Length = 595
Score = 51.6 bits (122), Expect = 7e-07
Identities = 48/190 (25%), Positives = 83/190 (43%), Gaps = 35/190 (18%)
Query: 82 INSSSVCVSSISENDNGISFTCRL---GRDQSVSVSVVLNVTFPP--------------- 123
I SS+ D+G S TC++ G +++ +V LN+++PP
Sbjct: 321 ITRSSMLSLIPQPQDHGTSLTCQVTLPGAGVTMTRAVRLNISYPPQNLTMTVFQGDGTAS 380
Query: 124 -LLSGNDFQTVEEGSNVKLVCNVKANPQAQMMWYKNSSLLDLEKSRHQIQQTSESFQLSI 182
L +V EG ++ LVC V +NP A++ W S L L S Q+S L +
Sbjct: 381 TTLRNGSALSVLEGQSLHLVCAVDSNPPARLSWTWGS--LTLSPS-----QSSNLGVLEL 433
Query: 183 TKVEKPDNGTYSCIAKSSLKTESLDFHLIVKDKTVGV--PIEPI-------IAACVVIFL 233
+V D G ++C A++ L ++ + L ++++ G PI + A ++FL
Sbjct: 434 PRVHVKDEGEFTCRAQNPLGSQHISLSLSLQNEYTGKMRPISGVTLGAFGGAGATALVFL 493
Query: 234 TLCFGLIARR 243
C + R
Sbjct: 494 YFCIIFVVVR 503
>gi|126012571 heparan sulfate proteoglycan 2 [Homo sapiens]
Length = 4391
Score = 50.4 bits (119), Expect = 2e-06
Identities = 49/190 (25%), Positives = 86/190 (45%), Gaps = 27/190 (14%)
Query: 47 GSQASLICAVQNHTREEELLWYREEGRVDLKSGNKINSSSVCVSSISENDNGISFTCRLG 106
G L C V + + WY+ G L S ++I S + + ++ D+G + C +
Sbjct: 2548 GHTLDLNCLVASQA-PHTITWYKRGG--SLPSRHQIVGSRLRIPQVTPADSG-EYVCHVS 2603
Query: 107 -----RDQSVSVSV-------VLNVTFPPLLSGNDFQTVEEGSNVKLVCNVKANPQAQMM 154
R+ S+ V++ V +V+ PP+ + TV EG + L C V PQA +
Sbjct: 2604 NGAGSRETSLIVTIQGSGSSHVPSVS-PPIRIESSSPTVVEGQTLDLNCVVARQPQAIIT 2662
Query: 155 WYKNSSLLDLEKSRHQIQQTSESFQLSITKVEKPDNGTYSCIAKSSLKTESLDFHLIVK- 213
WYK L SRHQ + L + ++ D+G Y C A +++ ++L+ +++
Sbjct: 2663 WYKRGGSL---PSRHQ----THGSHLRLHQMSVADSGEYVCRANNNI--DALEASIVISV 2713
Query: 214 DKTVGVPIEP 223
+ G P P
Sbjct: 2714 SPSAGSPSAP 2723
Score = 47.4 bits (111), Expect = 1e-05
Identities = 39/164 (23%), Positives = 71/164 (43%), Gaps = 19/164 (11%)
Query: 47 GSQASLICAVQNHTREEELLWYREEGRVDLKSGNKINSSSVCVSSISENDNGISFTCRL- 105
G L C V + + W++ G L + ++ + S + + ++ D+G + C +
Sbjct: 2166 GQTLDLNCVVPGQAHAQ-VTWHKRGG--SLPARHQTHGSLLRLHQVTPADSG-EYVCHVV 2221
Query: 106 GRDQSVSVSVVLNVT-------FPPLLSGNDFQTVEEGSNVKLVCNVKANPQAQMMWYKN 158
G + SV++ + PP+ + TV EG + L C V AQ+ WYK
Sbjct: 2222 GTSGPLEASVLVTIEASVIPGPIPPVRIESSSSTVAEGQTLDLSCVVAGQAHAQVTWYKR 2281
Query: 159 SSLLDLEKSRHQIQQTSESFQLSITKVEKPDNGTYSCIAKSSLK 202
L +RHQ++ + +L I + D G Y C A + ++
Sbjct: 2282 GGSL---PARHQVRGS----RLYIFQASPADAGQYVCRASNGME 2318
Score = 45.1 bits (105), Expect = 6e-05
Identities = 46/200 (23%), Positives = 77/200 (38%), Gaps = 26/200 (13%)
Query: 47 GSQASLICAVQNHTREEELLWYREEGRVDLKSGNKINSSSVCVSSISENDNGISFTCR-L 105
G L C V + + W++ G L S ++ S + + +S D+G + CR +
Sbjct: 2741 GETLDLNCVVPGQAHAQ-VTWHKRGG--SLPSHHQTRGSRLRLHHVSPADSG-EYVCRVM 2796
Query: 106 GRDQSVSVSVVLNVTF--------------PPLLSGNDFQTVEEGSNVKLVCNVKANPQA 151
G + SV++ + PP+ V EG + L C V A
Sbjct: 2797 GSSGPLEASVLVTIEASGSSAVHVPAPGGAPPIRIEPSSSRVAEGQTLDLKCVVPGQAHA 2856
Query: 152 QMMWYKNSSLLDLEKSRHQIQQTSESFQLSITKVEKPDNGTYSCIAKSSLKTESLDFHLI 211
Q+ W+K L +RHQ+ L + +V D+G YSC S T +
Sbjct: 2857 QVTWHKRGGNL---PARHQVHGP----LLRLNQVSPADSGEYSCQVTGSSGTLEASVLVT 2909
Query: 212 VKDKTVGVPIEPIIAACVVI 231
++ + G P +A + I
Sbjct: 2910 IEPSSPGPIPAPGLAQPIYI 2929
Score = 44.7 bits (104), Expect = 8e-05
Identities = 47/205 (22%), Positives = 80/205 (39%), Gaps = 27/205 (13%)
Query: 36 KTENYILDTTPGSQASLICAVQNHTREEELLWYREEGRVDLKSGNKINSSSVCVSSISEN 95
K E+ T G L C V + ++ WYR G L +++ S + + +S
Sbjct: 2054 KIESSSPSVTEGQTLDLNCVVAG-SAHAQVTWYRRGG--SLPPHTQVHGSRLRLPQVSPA 2110
Query: 96 DNGISFTCRLG-----RDQSVSVSVVLNVTFPPLLSGNDFQT-----------VEEGSNV 139
D+G + CR+ ++ S++VSV+ P + T V EG +
Sbjct: 2111 DSG-EYVCRVENGSGPKEASITVSVLHGTHSGPSYTPVPGSTRPIRIEPSSSHVAEGQTL 2169
Query: 140 KLVCNVKANPQAQMMWYKNSSLLDLEKSRHQIQQTSESFQLSITKVEKPDNGTYSCIAKS 199
L C V AQ+ W+K L +RHQ + L + +V D+G Y C
Sbjct: 2170 DLNCVVPGQAHAQVTWHKRGGSL---PARHQ----THGSLLRLHQVTPADSGEYVCHVVG 2222
Query: 200 SLKTESLDFHLIVKDKTVGVPIEPI 224
+ + ++ + PI P+
Sbjct: 2223 TSGPLEASVLVTIEASVIPGPIPPV 2247
Score = 44.3 bits (103), Expect = 1e-04
Identities = 41/171 (23%), Positives = 68/171 (39%), Gaps = 23/171 (13%)
Query: 47 GSQASLICAVQNHTREEELLWYREEGRVDLKSGNKINSSSVCVSSISENDNGISFTCRLG 106
G L C V + + WY+ G L + +++ S + + S D G + CR
Sbjct: 2259 GQTLDLSCVVAGQAHAQ-VTWYKRGG--SLPARHQVRGSRLYIFQASPADAG-QYVCRAS 2314
Query: 107 RDQSVSVSVVL------NVTFP-----PLLSGNDFQTVEEGSNVKLVCNVKANPQAQMMW 155
S++V + N+ +P P+ V EG + L C V AQ+ W
Sbjct: 2315 NGMEASITVTVTGTQGANLAYPAGSTQPIRIEPSSSQVAEGQTLDLNCVVPGQSHAQVTW 2374
Query: 156 YKNSSLLDLEKSRHQIQQTSESFQLSITKVEKPDNGTYSC-IAKSSLKTES 205
+K L + RHQ + L + + D+G Y C + SS+ E+
Sbjct: 2375 HKRGGSLPV---RHQ----THGSLLRLYQASPADSGEYVCRVLGSSVPLEA 2418
Score = 44.3 bits (103), Expect = 1e-04
Identities = 44/194 (22%), Positives = 78/194 (40%), Gaps = 36/194 (18%)
Query: 27 TSSVLTVNGKTENYILDTTP-------------GSQASLICAVQNHTREEELLWYREEGR 73
TS ++T+ G +++ +P G L C V + + WY+ G
Sbjct: 2611 TSLIVTIQGSGSSHVPSVSPPIRIESSSPTVVEGQTLDLNCVVARQP-QAIITWYKRGG- 2668
Query: 74 VDLKSGNKINSSSVCVSSISENDNGISFTCRLGRD-QSVSVSVVLNVT-----------F 121
L S ++ + S + + +S D+G + CR + ++ S+V++V+
Sbjct: 2669 -SLPSRHQTHGSHLRLHQMSVADSG-EYVCRANNNIDALEASIVISVSPSAGSPSAPGSS 2726
Query: 122 PPLLSGNDFQTVEEGSNVKLVCNVKANPQAQMMWYKNSSLLDLEKSRHQIQQTSESFQLS 181
P+ + V EG + L C V AQ+ W+K L S HQ + +L
Sbjct: 2727 MPIRIESSSSHVAEGETLDLNCVVPGQAHAQVTWHKRGGSL---PSHHQ----TRGSRLR 2779
Query: 182 ITKVEKPDNGTYSC 195
+ V D+G Y C
Sbjct: 2780 LHHVSPADSGEYVC 2793
Score = 43.9 bits (102), Expect = 1e-04
Identities = 43/170 (25%), Positives = 71/170 (41%), Gaps = 7/170 (4%)
Query: 47 GSQASLICAVQNHTREEELLWYREEGRVDLKSGNKINSSSVCVSSISENDNGISFTCRLG 106
G AS C + + L W ++ N S + + +++G ++ C
Sbjct: 3036 GQDASFKCLIHDGAAPISLEWKTRNQELEDNVHISPNGSIITIVGTRPSNHG-TYRCVAS 3094
Query: 107 RDQSVSVSVV-LNVTFPPLLS--GNDFQTVEEGSNVKLVCNVKANPQAQMMWYKNSSL-L 162
V+ SVV L+V PP +S V+ G V L C P++ W + SS
Sbjct: 3095 NAYGVAQSVVNLSVHGPPTVSVLPEGPVWVKVGKAVTLECVSAGEPRSSARWTRISSTPA 3154
Query: 163 DLEKSRHQIQQTSESFQLSITKVEKPDNGTYSCIAKSSLKTESLDFHLIV 212
LE+ + + + Q+S K D GTY C+A+++L T +IV
Sbjct: 3155 KLEQRTYGLMDSHAVLQISSAKPS--DAGTYVCLAQNALGTAQKQVEVIV 3202
Score = 43.1 bits (100), Expect = 2e-04
Identities = 40/183 (21%), Positives = 76/183 (41%), Gaps = 22/183 (12%)
Query: 47 GSQASLICAVQNHTREEELLWYREEGRVDLKSGNKINSSSVCVSSISENDNGISFTCR-L 105
G L C V + + + W++ G + ++ ++ + S + + S D+G + CR L
Sbjct: 2355 GQTLDLNCVVPGQSHAQ-VTWHKRGGSLPVR--HQTHGSLLRLYQASPADSG-EYVCRVL 2410
Query: 106 GRDQSVSVSVVLNV----------TFPPLLSGNDFQTVEEGSNVKLVCNVKANPQAQMMW 155
G + SV++ + P + + V EG + L C V AQ+ W
Sbjct: 2411 GSSVPLEASVLVTIEPAGSVPALGVTPTVRIESSSSQVAEGQTLDLNCLVAGQAHAQVTW 2470
Query: 156 YKNSSLLDLEKSRHQIQQTSESFQLSITKVEKPDNGTYSCIAKSSLKTESLDFHLIVKDK 215
+K L +RHQ+ + +L + +V D+G Y C S T+ + ++ +
Sbjct: 2471 HKRGGSL---PARHQVHGS----RLRLLQVTPADSGEYVCRVVGSSGTQEASVLVTIQQR 2523
Query: 216 TVG 218
G
Sbjct: 2524 LSG 2526
Score = 42.4 bits (98), Expect = 4e-04
Identities = 39/166 (23%), Positives = 70/166 (42%), Gaps = 24/166 (14%)
Query: 47 GSQASLICAVQNHTREEELLWYREEGRVDLKSGNKINSSSVCVSSISENDNGISFTCRL- 105
G L C V + + W++ G +L + ++++ + ++ +S D+G ++C++
Sbjct: 2841 GQTLDLKCVVPGQAHAQ-VTWHKRGG--NLPARHQVHGPLLRLNQVSPADSG-EYSCQVT 2896
Query: 106 GRDQSVSVSVVLNVT------------FPPLLSGNDFQTVEEGSNVKLVCNVKANPQAQM 153
G ++ SV++ + P+ V EG + L C V AQ+
Sbjct: 2897 GSSGTLEASVLVTIEPSSPGPIPAPGLAQPIYIEASSSHVTEGQTLDLNCVVPGQAHAQV 2956
Query: 154 MWYKNSSLLDLEKSRHQIQQTSESFQLSITKVEKPDNGTYSCIAKS 199
WYK L +RHQ + QL + V D+G Y C A S
Sbjct: 2957 TWYKRGGSL---PARHQ----THGSQLRLHLVSPADSGEYVCRAAS 2995
Score = 40.0 bits (92), Expect = 0.002
Identities = 41/171 (23%), Positives = 74/171 (43%), Gaps = 15/171 (8%)
Query: 47 GSQASLICAVQNHTREEELLWYREEGRVDLKSGNKINSSSVCVSSISENDNGISFTCRL- 105
G+ CAV + R +L W++E G+ L G+ + + + ++ ++ G ++ C+
Sbjct: 3414 GASVEFHCAVPSD-RGTQLRWFKEGGQ--LPPGHSVQDGVLRIQNLDQSCQG-TYICQAH 3469
Query: 106 ---GRDQSVSVSVVLNVTFPPLLSGNDFQTVEEGSNVKLVCNVKANPQAQMMWYKNSSLL 162
G+ Q+ + V+ + + QTV G V+ C +P+ Q+ W K L
Sbjct: 3470 GPWGKAQASAQLVIQALPSVLINIRTSVQTVVVGHAVEFECLALGDPKPQVTWSKVGGHL 3529
Query: 163 DLEKSRHQIQQTSESFQLSITKVEKPDNGTYSCIAKSSLKTESLDFHLIVK 213
R I Q+ + I VE D G Y C A ++ T L+V+
Sbjct: 3530 -----RPGIVQSGG--VVRIAHVELADAGQYRCTATNAAGTTQSHVLLLVQ 3573
Score = 36.6 bits (83), Expect = 0.023
Identities = 32/138 (23%), Positives = 59/138 (42%), Gaps = 14/138 (10%)
Query: 65 LLWYREEGRVDLKS-GNKINSSSVCVSSISENDNGISF---TCRLGRDQSVSVSVVLNVT 120
+ W +E G + ++ + + +++ + +I+ D G T G Q+ VVL+ +
Sbjct: 1987 ITWRKEGGSLPPQARSERTDIATLLIPAITTADAGFYLCVATSPAGTAQARIQVVVLSAS 2046
Query: 121 F---PPLLSGNDFQTVEEGSNVKLVCNVKANPQAQMMWYKNSSLLDLEKSRHQIQQTSES 177
PP+ + +V EG + L C V + AQ+ WY+ L H
Sbjct: 2047 DASPPPVKIESSSPSVTEGQTLDLNCVVAGSAHAQVTWYRRGGSLPPHTQVH-------G 2099
Query: 178 FQLSITKVEKPDNGTYSC 195
+L + +V D+G Y C
Sbjct: 2100 SRLRLPQVSPADSGEYVC 2117
Score = 33.1 bits (74), Expect = 0.25
Identities = 27/149 (18%), Positives = 59/149 (39%), Gaps = 10/149 (6%)
Query: 80 NKINSSSVCVSSISENDNGISFTCRLGRDQSVSVSVVLNVTFPPLLSG-NDFQTVEEGSN 138
+++ ++ + +++ D+G +++L+V PP + + +V+ G
Sbjct: 3256 HRLEGDTLIIPRVAQQDSGQYICNATSPAGHAEATIILHVESPPYATTVPEHASVQAGET 3315
Query: 139 VKLVCNVKANPQAQMMWYK-NSSLLDLEKSRHQIQQTSESFQLSITKVEKPDNGTYSCIA 197
V+L C P W + SSL +R+++ L + D+G Y C
Sbjct: 3316 VQLQCLAHGTPPLTFQWSRVGSSLPGRATARNEL--------LHFERAAPEDSGRYRCRV 3367
Query: 198 KSSLKTESLDFHLIVKDKTVGVPIEPIIA 226
+ + + L+V+ +P I A
Sbjct: 3368 TNKVGSAEAFAQLLVQGPPGSLPATSIPA 3396
Score = 31.2 bits (69), Expect = 0.96
Identities = 20/80 (25%), Positives = 30/80 (37%), Gaps = 4/80 (5%)
Query: 133 VEEGSNVKLVCNVKANPQAQMMWYKNSSLLDLEKSRHQIQQTSESFQLSITKVEKPDNGT 192
V G V+L C P A + W K L + + ++ L I + D G
Sbjct: 1967 VHAGRTVRLYCRAAGVPSATITWRKEGGSLPPQAR----SERTDIATLLIPAITTADAGF 2022
Query: 193 YSCIAKSSLKTESLDFHLIV 212
Y C+A S T ++V
Sbjct: 2023 YLCVATSPAGTAQARIQVVV 2042
Score = 30.8 bits (68), Expect = 1.3
Identities = 22/68 (32%), Positives = 28/68 (41%), Gaps = 7/68 (10%)
Query: 132 TVEEGSNVKLVCNVKANPQAQMMWYKNSSLLDLEKSRHQIQQTSESFQLSITKVEKPDNG 191
TVE G L C+ +P + W K S L Q E L I +V + D+G
Sbjct: 3222 TVEAGHTATLRCSATGSPAPTIHWSKLRSPLPW-------QHRLEGDTLIIPRVAQQDSG 3274
Query: 192 TYSCIAKS 199
Y C A S
Sbjct: 3275 QYICNATS 3282
Score = 28.1 bits (61), Expect = 8.1
Identities = 30/143 (20%), Positives = 54/143 (37%), Gaps = 23/143 (16%)
Query: 60 TREEELLWYR-----EEGRVDLKSGNKINSSSVCVSSISENDNGISFTCRLGRDQSVSVS 114
T ELL + + GR + NK+ S+ + + G S+ +
Sbjct: 3344 TARNELLHFERAAPEDSGRYRCRVTNKVGSAEAFAQLLVQGPPG-----------SLPAT 3392
Query: 115 VVLNVTFPPLLSGNDFQTVEEGSNVKLVCNVKANPQAQMMWYKNSSLLDLEKSRHQIQQT 174
+ + P + +T G++V+ C V ++ Q+ W+K L H +Q
Sbjct: 3393 SIPAGSTPTVQVTPQLETKSIGASVEFHCAVPSDRGTQLRWFKEGGQL---PPGHSVQDG 3449
Query: 175 SESFQLSITKVEKPDNGTYSCIA 197
L I +++ GTY C A
Sbjct: 3450 ----VLRIQNLDQSCQGTYICQA 3468
>gi|15826840 PTK7 protein tyrosine kinase 7 isoform a precursor
[Homo sapiens]
Length = 1070
Score = 50.4 bits (119), Expect = 2e-06
Identities = 43/162 (26%), Positives = 73/162 (45%), Gaps = 17/162 (10%)
Query: 45 TPGSQASLICAVQNHTREEELLWYREEGRVDLKSGNKI--NSSSVCVSSISENDNGISFT 102
T GS+ + C E + W E V L + ++ + +++I+E+D G+ +T
Sbjct: 334 TAGSEERVTCLPPKGLPEPSVWW--EHAGVRLPTHGRVYQKGHELVLANIAESDAGV-YT 390
Query: 103 CRLG-----RDQSVSVSVVLNVTFPPLLSGNDFQTVEEGSNVKLVCNVKANPQAQMMWYK 157
C R Q V+++V T P L +EEG L C +A P+ ++WY+
Sbjct: 391 CHAANLAGQRRQDVNITVA---TVPSWLKKPQDSQLEEGKPGYLDCLTQATPKPTVVWYR 447
Query: 158 NSSLLDLEKSRHQIQQTSESFQLSITKVEKPDNGTYSCIAKS 199
N L+ E SR ++ + L I VE D Y C++ +
Sbjct: 448 NQMLIS-EDSRFEVFKNG---TLRINSVEVYDGTWYRCMSST 485
Score = 41.6 bits (96), Expect = 7e-04
Identities = 47/228 (20%), Positives = 88/228 (38%), Gaps = 21/228 (9%)
Query: 49 QASLICAVQNHTREEELLWYREEGRVDLKSGNKINSSSVCVSSISENDNGISFTCRLGRD 108
+A++ C+ + + W R +G L N+ ++ + ++ +D G ++TC
Sbjct: 519 EATVPCSATGREKPT-IKWERADGS-SLPEWVTDNAGTLHFARVTRDDAG-NYTCIASNG 575
Query: 109 QSVSVSVVLNVTFPPLLSGN---DFQTVEEGSNVKLVCNVKANPQAQMMWYKNSSLLDLE 165
+ + +T ++ + TV +G L C + +P+ + W +LD
Sbjct: 576 PQGQIRAHVQLTVAVFITFKVEPERTTVYQGHTALLQCEAQGDPKPLIQWKGKDRILDPT 635
Query: 166 KSRHQIQQTSESFQLSITKVEKPDNGTYSCIAKSSLKTESLDFHLIVKDKTVGVPIE--- 222
K ++ ++ L I V D+G Y+CIA +S + + L V DK V E
Sbjct: 636 KLGPRMH-IFQNGSLVIHDVAPEDSGRYTCIAGNSCNIKHTEAPLYVVDKPVPEESEGPG 694
Query: 223 -----------PIIAACVVIFLTLCFGLIARRKKIMKLCMKDKDPHSE 259
+ V ++ GL+ KK K K P E
Sbjct: 695 SPPPYKMIQTIGLSVGAAVAYIIAVLGLMFYCKKRCKAKRLQKQPEGE 742
Score = 35.4 bits (80), Expect = 0.051
Identities = 20/86 (23%), Positives = 43/86 (50%), Gaps = 4/86 (4%)
Query: 133 VEEGSNVKLVCNVKANPQAQMMWYKNSSLLDLEKSRHQIQQTSESFQLSITKVEKPDNGT 192
++ + V L C++ +P+ W+++ + L +S H + +S+ L++ +G
Sbjct: 140 IQPQTQVTLRCHIDGHPRPTYQWFRDGTPLSDGQSNHTV--SSKERNLTLRPAGPEHSGL 197
Query: 193 YSCIAKSSL--KTESLDFHLIVKDKT 216
YSC A S+ S +F L + D++
Sbjct: 198 YSCCAHSAFGQACSSQNFTLSIADES 223
Score = 30.0 bits (66), Expect = 2.1
Identities = 25/100 (25%), Positives = 42/100 (42%), Gaps = 16/100 (16%)
Query: 116 VLNVTFPPLLSGNDF----------QTVEEGSNVKLVCNVKANPQAQMMWYKNSSLLDLE 165
+L+V PLL G Q +G L C V+A + W LLD
Sbjct: 16 LLSVLLLPLLGGTQTAIVFIKQPSSQDALQGRRALLRCEVEAPGPVHVYW-----LLDGA 70
Query: 166 KSRHQIQQTSESFQLSITKVEK-PDNGTYSCIAKSSLKTE 204
+ ++ ++ LS V++ D+GT+ C+A+ + E
Sbjct: 71 PVQDTERRFAQGSSLSFAAVDRLQDSGTFQCVARDDVTGE 110
>gi|22902130 PTK7 protein tyrosine kinase 7 isoform d precursor
[Homo sapiens]
Length = 1014
Score = 50.4 bits (119), Expect = 2e-06
Identities = 43/162 (26%), Positives = 73/162 (45%), Gaps = 17/162 (10%)
Query: 45 TPGSQASLICAVQNHTREEELLWYREEGRVDLKSGNKI--NSSSVCVSSISENDNGISFT 102
T GS+ + C E + W E V L + ++ + +++I+E+D G+ +T
Sbjct: 334 TAGSEERVTCLPPKGLPEPSVWW--EHAGVRLPTHGRVYQKGHELVLANIAESDAGV-YT 390
Query: 103 CRLG-----RDQSVSVSVVLNVTFPPLLSGNDFQTVEEGSNVKLVCNVKANPQAQMMWYK 157
C R Q V+++V T P L +EEG L C +A P+ ++WY+
Sbjct: 391 CHAANLAGQRRQDVNITVA---TVPSWLKKPQDSQLEEGKPGYLDCLTQATPKPTVVWYR 447
Query: 158 NSSLLDLEKSRHQIQQTSESFQLSITKVEKPDNGTYSCIAKS 199
N L+ E SR ++ + L I VE D Y C++ +
Sbjct: 448 NQMLIS-EDSRFEVFKNG---TLRINSVEVYDGTWYRCMSST 485
Score = 35.4 bits (80), Expect = 0.051
Identities = 20/86 (23%), Positives = 43/86 (50%), Gaps = 4/86 (4%)
Query: 133 VEEGSNVKLVCNVKANPQAQMMWYKNSSLLDLEKSRHQIQQTSESFQLSITKVEKPDNGT 192
++ + V L C++ +P+ W+++ + L +S H + +S+ L++ +G
Sbjct: 140 IQPQTQVTLRCHIDGHPRPTYQWFRDGTPLSDGQSNHTV--SSKERNLTLRPAGPEHSGL 197
Query: 193 YSCIAKSSL--KTESLDFHLIVKDKT 216
YSC A S+ S +F L + D++
Sbjct: 198 YSCCAHSAFGQACSSQNFTLSIADES 223
Score = 30.0 bits (66), Expect = 2.1
Identities = 25/100 (25%), Positives = 42/100 (42%), Gaps = 16/100 (16%)
Query: 116 VLNVTFPPLLSGNDF----------QTVEEGSNVKLVCNVKANPQAQMMWYKNSSLLDLE 165
+L+V PLL G Q +G L C V+A + W LLD
Sbjct: 16 LLSVLLLPLLGGTQTAIVFIKQPSSQDALQGRRALLRCEVEAPGPVHVYW-----LLDGA 70
Query: 166 KSRHQIQQTSESFQLSITKVEK-PDNGTYSCIAKSSLKTE 204
+ ++ ++ LS V++ D+GT+ C+A+ + E
Sbjct: 71 PVQDTERRFAQGSSLSFAAVDRLQDSGTFQCVARDDVTGE 110
>gi|22902126 PTK7 protein tyrosine kinase 7 isoform b precursor
[Homo sapiens]
Length = 1030
Score = 50.4 bits (119), Expect = 2e-06
Identities = 43/162 (26%), Positives = 73/162 (45%), Gaps = 17/162 (10%)
Query: 45 TPGSQASLICAVQNHTREEELLWYREEGRVDLKSGNKI--NSSSVCVSSISENDNGISFT 102
T GS+ + C E + W E V L + ++ + +++I+E+D G+ +T
Sbjct: 334 TAGSEERVTCLPPKGLPEPSVWW--EHAGVRLPTHGRVYQKGHELVLANIAESDAGV-YT 390
Query: 103 CRLG-----RDQSVSVSVVLNVTFPPLLSGNDFQTVEEGSNVKLVCNVKANPQAQMMWYK 157
C R Q V+++V T P L +EEG L C +A P+ ++WY+
Sbjct: 391 CHAANLAGQRRQDVNITVA---TVPSWLKKPQDSQLEEGKPGYLDCLTQATPKPTVVWYR 447
Query: 158 NSSLLDLEKSRHQIQQTSESFQLSITKVEKPDNGTYSCIAKS 199
N L+ E SR ++ + L I VE D Y C++ +
Sbjct: 448 NQMLIS-EDSRFEVFKNG---TLRINSVEVYDGTWYRCMSST 485
Score = 41.2 bits (95), Expect = 0.001
Identities = 44/212 (20%), Positives = 82/212 (38%), Gaps = 25/212 (11%)
Query: 71 EGRVDLKSGNKI------NSSSVCVSSISENDNGISFTCRLGRDQSVSVSVVLNVTFPPL 124
+ RV + G+ + N+ ++ + ++ +D G ++TC + + +T
Sbjct: 493 QARVQVLDGSSLPEWVTDNAGTLHFARVTRDDAG-NYTCIASNGPQGQIRAHVQLTVAVF 551
Query: 125 LSGN---DFQTVEEGSNVKLVCNVKANPQAQMMWYKNSSLLDLEKSRHQIQQTSESFQLS 181
++ + TV +G L C + +P+ + W +LD K ++ ++ L
Sbjct: 552 ITFKVEPERTTVYQGHTALLQCEAQGDPKPLIQWKGKDRILDPTKLGPRMH-IFQNGSLV 610
Query: 182 ITKVEKPDNGTYSCIAKSSLKTESLDFHLIVKDKTVGVPIE--------------PIIAA 227
I V D+G Y+CIA +S + + L V DK V E +
Sbjct: 611 IHDVAPEDSGRYTCIAGNSCNIKHTEAPLYVVDKPVPEESEGPGSPPPYKMIQTIGLSVG 670
Query: 228 CVVIFLTLCFGLIARRKKIMKLCMKDKDPHSE 259
V ++ GL+ KK K K P E
Sbjct: 671 AAVAYIIAVLGLMFYCKKRCKAKRLQKQPEGE 702
Score = 35.4 bits (80), Expect = 0.051
Identities = 20/86 (23%), Positives = 43/86 (50%), Gaps = 4/86 (4%)
Query: 133 VEEGSNVKLVCNVKANPQAQMMWYKNSSLLDLEKSRHQIQQTSESFQLSITKVEKPDNGT 192
++ + V L C++ +P+ W+++ + L +S H + +S+ L++ +G
Sbjct: 140 IQPQTQVTLRCHIDGHPRPTYQWFRDGTPLSDGQSNHTV--SSKERNLTLRPAGPEHSGL 197
Query: 193 YSCIAKSSL--KTESLDFHLIVKDKT 216
YSC A S+ S +F L + D++
Sbjct: 198 YSCCAHSAFGQACSSQNFTLSIADES 223
Score = 30.0 bits (66), Expect = 2.1
Identities = 25/100 (25%), Positives = 42/100 (42%), Gaps = 16/100 (16%)
Query: 116 VLNVTFPPLLSGNDF----------QTVEEGSNVKLVCNVKANPQAQMMWYKNSSLLDLE 165
+L+V PLL G Q +G L C V+A + W LLD
Sbjct: 16 LLSVLLLPLLGGTQTAIVFIKQPSSQDALQGRRALLRCEVEAPGPVHVYW-----LLDGA 70
Query: 166 KSRHQIQQTSESFQLSITKVEK-PDNGTYSCIAKSSLKTE 204
+ ++ ++ LS V++ D+GT+ C+A+ + E
Sbjct: 71 PVQDTERRFAQGSSLSFAAVDRLQDSGTFQCVARDDVTGE 110
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.131 0.377
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,416,286
Number of Sequences: 37866
Number of extensions: 378841
Number of successful extensions: 2656
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 160
Number of HSP's successfully gapped in prelim test: 212
Number of HSP's that attempted gapping in prelim test: 1198
Number of HSP's gapped (non-prelim): 1267
length of query: 262
length of database: 18,247,518
effective HSP length: 100
effective length of query: 162
effective length of database: 14,460,918
effective search space: 2342668716
effective search space used: 2342668716
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.