Guide to the Human Genome
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Search of human proteins with 131888281

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|131888281 hypothetical protein LOC55216 isoform b [Homo
sapiens]
         (292 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|131888281 hypothetical protein LOC55216 isoform b [Homo sapiens]   589   e-169
gi|131889432 hypothetical protein LOC55216 isoform a [Homo sapiens]   585   e-167
gi|131889391 hypothetical protein LOC55216 isoform a [Homo sapiens]   585   e-167
gi|168229156 NFKB activating protein [Homo sapiens]                    74   2e-13
gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1...    67   2e-11
gi|56090620 NFKB activating protein-like [Homo sapiens]                66   3e-11
gi|27734775 hypothetical protein LOC286499 [Homo sapiens]              63   3e-10
gi|91206454 hypothetical protein LOC257415 isoform 2 [Homo sapiens]    59   5e-09
gi|91206456 hypothetical protein LOC257415 isoform 1 [Homo sapiens]    59   5e-09
gi|4557509 cylicin 2 [Homo sapiens]                                    58   9e-09
gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]            56   3e-08
gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]            55   1e-07
gi|42560244 peptidylprolyl isomerase G [Homo sapiens]                  55   1e-07
gi|40068059 CBF1 interacting corepressor [Homo sapiens]                54   1e-07
gi|239508778 PREDICTED: hypothetical protein, partial [Homo sapi...    54   1e-07
gi|151301228 formin binding protein 3 [Homo sapiens]                   54   1e-07
gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo s...    54   1e-07
gi|50409756 SRp25 nuclear protein isoform 1 [Homo sapiens]             53   3e-07
gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ...    53   3e-07
gi|104526627 triadin [Homo sapiens]                                    53   3e-07
gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [...    53   3e-07
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap...    52   5e-07
gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens]    52   6e-07
gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens]    52   6e-07
gi|21040326 SON DNA-binding protein isoform F [Homo sapiens]           52   8e-07
gi|21040314 SON DNA-binding protein isoform B [Homo sapiens]           52   8e-07
gi|38788333 remodeling and spacing factor 1 [Homo sapiens]             51   1e-06
gi|148746195 trichohyalin [Homo sapiens]                               51   1e-06
gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain ...    51   1e-06
gi|50409738 SRp25 nuclear protein isoform 3 [Homo sapiens]             51   1e-06

>gi|131888281 hypothetical protein LOC55216 isoform b [Homo sapiens]
          Length = 292

 Score =  589 bits (1519), Expect = e-169
 Identities = 292/292 (100%), Positives = 292/292 (100%)

Query: 1   MSRIPLGKVLLRNVIRHTDAHNKIQEESDMWKIRELEKQMEDAYRGTKRKMLPSSSSRMR 60
           MSRIPLGKVLLRNVIRHTDAHNKIQEESDMWKIRELEKQMEDAYRGTKRKMLPSSSSRMR
Sbjct: 1   MSRIPLGKVLLRNVIRHTDAHNKIQEESDMWKIRELEKQMEDAYRGTKRKMLPSSSSRMR 60

Query: 61  SDGFDEESQRYYWRPKNEISGTLEDDFLKAKSWNKKFYDYEANMPDRWGHSGYKELYPEE 120
           SDGFDEESQRYYWRPKNEISGTLEDDFLKAKSWNKKFYDYEANMPDRWGHSGYKELYPEE
Sbjct: 61  SDGFDEESQRYYWRPKNEISGTLEDDFLKAKSWNKKFYDYEANMPDRWGHSGYKELYPEE 120

Query: 121 FETDSDQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDIT 180
           FETDSDQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDIT
Sbjct: 121 FETDSDQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDIT 180

Query: 181 ADSSSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEE 240
           ADSSSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEE
Sbjct: 181 ADSSSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEE 240

Query: 241 SEERDTKKTKRKKREKKAHTSVANNEIQERTNKRTNWKVATDERSAESSEDD 292
           SEERDTKKTKRKKREKKAHTSVANNEIQERTNKRTNWKVATDERSAESSEDD
Sbjct: 241 SEERDTKKTKRKKREKKAHTSVANNEIQERTNKRTNWKVATDERSAESSEDD 292


>gi|131889432 hypothetical protein LOC55216 isoform a [Homo sapiens]
          Length = 293

 Score =  585 bits (1507), Expect = e-167
 Identities = 292/293 (99%), Positives = 292/293 (99%), Gaps = 1/293 (0%)

Query: 1   MSRIPLGKVLLRNVIRHTDAHNKIQEESDMWKIRELEKQMEDAYRGTKRKMLPSSSSRMR 60
           MSRIPLGKVLLRNVIRHTDAHNKIQEESDMWKIRELEKQMEDAYRGTKRKMLPSSSSRMR
Sbjct: 1   MSRIPLGKVLLRNVIRHTDAHNKIQEESDMWKIRELEKQMEDAYRGTKRKMLPSSSSRMR 60

Query: 61  SDGFDEESQRYYWRPKNEISGTLEDDFLKAKSWNKKFYDYEANMPDRWGHSGYKELYPEE 120
           SDGFDEESQRYYWRPKNEISGTLEDDFLKAKSWNKKFYDYEANMPDRWGHSGYKELYPEE
Sbjct: 61  SDGFDEESQRYYWRPKNEISGTLEDDFLKAKSWNKKFYDYEANMPDRWGHSGYKELYPEE 120

Query: 121 FETDS-DQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDI 179
           FETDS DQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDI
Sbjct: 121 FETDSSDQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDI 180

Query: 180 TADSSSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSE 239
           TADSSSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSE
Sbjct: 181 TADSSSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSE 240

Query: 240 ESEERDTKKTKRKKREKKAHTSVANNEIQERTNKRTNWKVATDERSAESSEDD 292
           ESEERDTKKTKRKKREKKAHTSVANNEIQERTNKRTNWKVATDERSAESSEDD
Sbjct: 241 ESEERDTKKTKRKKREKKAHTSVANNEIQERTNKRTNWKVATDERSAESSEDD 293


>gi|131889391 hypothetical protein LOC55216 isoform a [Homo sapiens]
          Length = 293

 Score =  585 bits (1507), Expect = e-167
 Identities = 292/293 (99%), Positives = 292/293 (99%), Gaps = 1/293 (0%)

Query: 1   MSRIPLGKVLLRNVIRHTDAHNKIQEESDMWKIRELEKQMEDAYRGTKRKMLPSSSSRMR 60
           MSRIPLGKVLLRNVIRHTDAHNKIQEESDMWKIRELEKQMEDAYRGTKRKMLPSSSSRMR
Sbjct: 1   MSRIPLGKVLLRNVIRHTDAHNKIQEESDMWKIRELEKQMEDAYRGTKRKMLPSSSSRMR 60

Query: 61  SDGFDEESQRYYWRPKNEISGTLEDDFLKAKSWNKKFYDYEANMPDRWGHSGYKELYPEE 120
           SDGFDEESQRYYWRPKNEISGTLEDDFLKAKSWNKKFYDYEANMPDRWGHSGYKELYPEE
Sbjct: 61  SDGFDEESQRYYWRPKNEISGTLEDDFLKAKSWNKKFYDYEANMPDRWGHSGYKELYPEE 120

Query: 121 FETDS-DQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDI 179
           FETDS DQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDI
Sbjct: 121 FETDSSDQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDI 180

Query: 180 TADSSSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSE 239
           TADSSSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSE
Sbjct: 181 TADSSSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSE 240

Query: 240 ESEERDTKKTKRKKREKKAHTSVANNEIQERTNKRTNWKVATDERSAESSEDD 292
           ESEERDTKKTKRKKREKKAHTSVANNEIQERTNKRTNWKVATDERSAESSEDD
Sbjct: 241 ESEERDTKKTKRKKREKKAHTSVANNEIQERTNKRTNWKVATDERSAESSEDD 293


>gi|168229156 NFKB activating protein [Homo sapiens]
          Length = 415

 Score = 73.6 bits (179), Expect = 2e-13
 Identities = 59/227 (25%), Positives = 98/227 (43%), Gaps = 25/227 (11%)

Query: 43  AYRGTKRKMLPSSSSRMRSDGFDEESQRYYW----------RPKNEISGTLEDDFLKAKS 92
           +YR   R       S  R   F   S   Y+          +P   +     ++ L+ K 
Sbjct: 71  SYRSRSRSRSRERPSAPRGIPFASASSSVYYGSYSRPYGSDKPWPSLLDKEREESLRQKR 130

Query: 93  WNKKFYDYEANMPDRWGHSGYKELYPEEFETDSDQ----QDITNGKKTSPQVKSSTHESR 148
            +++    E   P+ WG      L P+  E DSD+    +D    K T+    S   + +
Sbjct: 131 LSERERIGELGAPEVWG------LSPKNPEPDSDEHTPVEDEEPKKSTTSASTSEEEKKK 184

Query: 149 KHKKSKKSHKKKQKKRSHKKQKKSKKEATDITADSSSEFSEETGASGTRKGKQPHKRKKK 208
           K  +SK+  KK++KK+S K++ K   E +D  +DS ++ S+E      +K K+  K+KK 
Sbjct: 185 KSSRSKERSKKRRKKKSSKRKHKKYSEDSDSDSDSETDSSDEDNKRRAKKAKKKEKKKKH 244

Query: 209 SRKKSLKKPALFLEAESNTSHSDDSASSSSEESEERDTKKTKRKKRE 255
             KK  KK      ++ +   S DS+S  S+E    +  K + K  E
Sbjct: 245 RSKKYKKK-----RSKKSRKESSDSSSKESQEEFLENPWKDRTKAEE 286



 Score = 44.3 bits (103), Expect = 1e-04
 Identities = 25/86 (29%), Positives = 43/86 (50%), Gaps = 7/86 (8%)

Query: 117 YPEEFETDSDQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEA 176
           Y E+ ++DSD +       T    + +   ++K KK +K  K + KK   K+ KKS+KE+
Sbjct: 209 YSEDSDSDSDSE-------TDSSDEDNKRRAKKAKKKEKKKKHRSKKYKKKRSKKSRKES 261

Query: 177 TDITADSSSEFSEETGASGTRKGKQP 202
           +D ++  S E   E       K ++P
Sbjct: 262 SDSSSKESQEEFLENPWKDRTKAEEP 287



 Score = 35.0 bits (79), Expect = 0.078
 Identities = 32/166 (19%), Positives = 65/166 (39%), Gaps = 17/166 (10%)

Query: 144 THESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITADSSS----EFSEETGASGTRKG 199
           TH+     +  ++   + + RS  +++ S        + SSS     +S   G+      
Sbjct: 57  THQLGGLSQGSRNQSYRSRSRSRSRERPSAPRGIPFASASSSVYYGSYSRPYGSDKPWPS 116

Query: 200 KQPHKRKKKSRKKSLKK---------PALFLEAESNTSHSDDSASSSSEESEERDTKKTK 250
               +R++  R+K L +         P ++  +  N     D  +   +E  ++ T    
Sbjct: 117 LLDKEREESLRQKRLSERERIGELGAPEVWGLSPKNPEPDSDEHTPVEDEEPKKSTTSAS 176

Query: 251 RKKREKKAHTSVANNEIQER----TNKRTNWKVATDERSAESSEDD 292
             + EKK  +S +    ++R    ++KR + K + D  S   SE D
Sbjct: 177 TSEEEKKKKSSRSKERSKKRRKKKSSKRKHKKYSEDSDSDSDSETD 222


>gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1
           [Homo sapiens]
          Length = 651

 Score = 67.0 bits (162), Expect = 2e-11
 Identities = 51/185 (27%), Positives = 82/185 (44%), Gaps = 14/185 (7%)

Query: 117 YPEEFETDSDQQDITNGKKTSPQVKSSTHESRKHKKSKK------SHKKKQKKRSHKKQK 170
           YPE   TD++  D  + +  S  +K ++    K K +KK      S  + + K S K +K
Sbjct: 366 YPES--TDTESGDAKDARNDSRNLKKASKNDDKKKDAKKITFSTDSESELESKESQKDEK 423

Query: 171 KSKKEATDITADSSSEFSEETGASG-----TRKGKQPHKRKKKSRKKSLKKPALFLEAES 225
           K KK++      S     E T A       ++KGK+  K+ KK  KK  KK      AES
Sbjct: 424 KDKKDSKTDNKKSVKNDEESTDADSEPKGDSKKGKKDEKKGKKDSKKDDKKKDAKKNAES 483

Query: 226 NTSHSDDSASSSSEES-EERDTKKTKRKKREKKAHTSVANNEIQERTNKRTNWKVATDER 284
               SD       + S E++ +KK  +K   K   ++ A  +   +T  +T+ K+   + 
Sbjct: 484 TEMESDLELKKDKKHSKEKKGSKKDIKKDARKDTESTDAEFDESSKTGFKTSTKIKGSDT 543

Query: 285 SAESS 289
            +E S
Sbjct: 544 ESEES 548



 Score = 52.0 bits (123), Expect = 6e-07
 Identities = 45/169 (26%), Positives = 74/169 (43%), Gaps = 19/169 (11%)

Query: 132 NGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITADSSSEFSEET 191
           N KK+S    + + +S+  KK  K  KK  KK   KK  K   E+TD  +  S +  ++T
Sbjct: 291 NAKKSSD---AESEDSKDAKKDSKKVKKNVKKDDKKKDVKKDTESTDAESGDSKDERKDT 347

Query: 192 GASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEERDTKKTKR 251
                   K   K KK  +KK  KK     + ES  +    + S + +++ + D KK   
Sbjct: 348 K-------KDKKKLKKDDKKKDTKKYPESTDTESGDAKDARNDSRNLKKASKNDDKKKDA 400

Query: 252 KK--------REKKAHTSVANNEIQERTNKRTNWK-VATDERSAESSED 291
           KK         E ++  S  + +  ++ +K  N K V  DE S ++  +
Sbjct: 401 KKITFSTDSESELESKESQKDEKKDKKDSKTDNKKSVKNDEESTDADSE 449



 Score = 50.8 bits (120), Expect = 1e-06
 Identities = 68/259 (26%), Positives = 113/259 (43%), Gaps = 19/259 (7%)

Query: 32  KIRELEKQME--DAYRGT---KRKMLPSSSSRMRSDGFDEESQRYYWRPKNEISGTLED- 85
           K ++++K  E  DA  G    +RK       +++ D   +++++Y      E SG  +D 
Sbjct: 322 KKKDVKKDTESTDAESGDSKDERKDTKKDKKKLKKDDKKKDTKKYPESTDTE-SGDAKDA 380

Query: 86  --DFLKAKSWNKKFYDYEANMPDRWGHSGYKELYPEEFETDS--DQQDI-TNGKKTSPQV 140
             D    K  +K     +      +      EL  +E + D   D++D  T+ KK+    
Sbjct: 381 RNDSRNLKKASKNDDKKKDAKKITFSTDSESELESKESQKDEKKDKKDSKTDNKKSVKND 440

Query: 141 KSSTH---ESRKHKKSKKSHKKKQKKRSHK--KQKKSKKEATDITADSSSEFSEETGASG 195
           + ST    E +   K  K  +KK KK S K  K+K +KK A     +S  E  ++   S 
Sbjct: 441 EESTDADSEPKGDSKKGKKDEKKGKKDSKKDDKKKDAKKNAESTEMESDLELKKDKKHSK 500

Query: 196 TRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEERDTKKTKRKKRE 255
            +KG +    KK +RK +    A F E+      +      S  ESEE   K   +KK +
Sbjct: 501 EKKGSK-KDIKKDARKDTESTDAEFDESSKTGFKTSTKIKGSDTESEESLYKPGAKKKID 559

Query: 256 KKAHTSVANNEIQERTNKR 274
           +   TS AN++++   +KR
Sbjct: 560 ESDGTS-ANSKMEGLESKR 577



 Score = 48.9 bits (115), Expect = 5e-06
 Identities = 40/172 (23%), Positives = 75/172 (43%), Gaps = 19/172 (11%)

Query: 124 DSDQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITADS 183
           D  ++D+   KK +    + + +S+  +K  K  KKK KK   KK  K   E+TD     
Sbjct: 320 DDKKKDV---KKDTESTDAESGDSKDERKDTKKDKKKLKKDDKKKDTKKYPESTD----- 371

Query: 184 SSEFSEETGASGTRKGKQPHKRKKKS--RKKSLKKPALFLEAESNTSHSDDSASSSSEES 241
               +E   A   R   +  K+  K+  +KK  KK     ++ES     +   S   E+ 
Sbjct: 372 ----TESGDAKDARNDSRNLKKASKNDDKKKDAKKITFSTDSESELESKE---SQKDEKK 424

Query: 242 EERDTKKTKRKKREKKAHTSVANNEIQ--ERTNKRTNWKVATDERSAESSED 291
           +++D+K   +K  +    ++ A++E +   +  K+   K   D +  +  +D
Sbjct: 425 DKKDSKTDNKKSVKNDEESTDADSEPKGDSKKGKKDEKKGKKDSKKDDKKKD 476



 Score = 43.1 bits (100), Expect = 3e-04
 Identities = 30/131 (22%), Positives = 60/131 (45%), Gaps = 9/131 (6%)

Query: 151 KKSKKSHKKKQKKRSHKKQKKSKKEATDITADSSSEFSEETGASGTRKGKQPHKRKKKSR 210
           + + K++  K  K + K  KK+ K+++D  ++ S +  +++        K     KK  +
Sbjct: 270 QNNSKNYSLKYTKYTKKDTKKNAKKSSDAESEDSKDAKKDSK-------KVKKNVKKDDK 322

Query: 211 KKSLKKPALFLEAESNTSHSDDSASSSSEESEERDTKKTKRKKREKKAHTSVANNEIQER 270
           KK +KK     +AES  S  +   +   ++  ++D KK   KK  +   T   + + ++ 
Sbjct: 323 KKDVKKDTESTDAESGDSKDERKDTKKDKKKLKKDDKKKDTKKYPES--TDTESGDAKDA 380

Query: 271 TNKRTNWKVAT 281
            N   N K A+
Sbjct: 381 RNDSRNLKKAS 391



 Score = 40.0 bits (92), Expect = 0.002
 Identities = 35/120 (29%), Positives = 56/120 (46%), Gaps = 27/120 (22%)

Query: 143 STHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITADSSSEFSEETGASGTRKGKQP 202
           S + S+ +      + KK  K++ KK           ++D+ SE S++         K+ 
Sbjct: 269 SQNNSKNYSLKYTKYTKKDTKKNAKK-----------SSDAESEDSKD--------AKKD 309

Query: 203 HKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEERDTKKTKR--KKREKKAHT 260
            K+ KK+ KK  KK  +  + ES  + S DS      + E +DTKK K+  KK +KK  T
Sbjct: 310 SKKVKKNVKKDDKKKDVKKDTESTDAESGDS------KDERKDTKKDKKKLKKDDKKKDT 363



 Score = 38.9 bits (89), Expect = 0.005
 Identities = 39/189 (20%), Positives = 76/189 (40%), Gaps = 23/189 (12%)

Query: 122 ETDSDQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITA 181
           ET+ + Q+     K   Q      ++ K   ++  H K   K+  K+ K S    ++I +
Sbjct: 180 ETNPESQNSKTVSKNCSQKDKKDSKNSKKTNTEFLHTKNNPKKDLKRSKTSNDPISEICS 239

Query: 182 DSS--SEFSEETGASG---------TRKGKQPH---------KRKKKSRKKSLKKPALFL 221
           ++S   +F    G S           R   Q +         K  KK  KK+ KK +   
Sbjct: 240 ENSLNVDFLMLVGQSDDESINFDAWLRNYSQNNSKNYSLKYTKYTKKDTKKNAKKSS--- 296

Query: 222 EAESNTSHSDDSASSSSEESEERDTKKTKRKKREKKAHTSVANNEIQERTNKRTNWKVAT 281
           +AES  S      S   +++ ++D KK   KK  +       +++ + +  K+   K+  
Sbjct: 297 DAESEDSKDAKKDSKKVKKNVKKDDKKKDVKKDTESTDAESGDSKDERKDTKKDKKKLKK 356

Query: 282 DERSAESSE 290
           D++  ++ +
Sbjct: 357 DDKKKDTKK 365



 Score = 38.5 bits (88), Expect = 0.007
 Identities = 36/161 (22%), Positives = 63/161 (39%), Gaps = 1/161 (0%)

Query: 83  LEDDFLKAKSWNKKFYDYEANMPDRWGHSGYKELYPEEFETDSDQQDITNGKKTSPQVKS 142
           +   F K   W   +       P R  ++    L   E++   D++  T  KK S +   
Sbjct: 77  IRHSFRKILQWPPIYTAAREQTPFRHLYTSKTHLKKAEYKKSKDEKGGTPLKKDSKKKGG 136

Query: 143 STHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITADSSSEFSEETGASGTRKGKQP 202
           S   + + K+  +   K+Q +      K S +      + SSSE + E+  S T   K  
Sbjct: 137 SYATNPESKQIVEEKTKRQNEADKTPLKSSHENEQSKKSKSSSETNPESQNSKT-VSKNC 195

Query: 203 HKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEE 243
            ++ KK  K S K    FL  ++N       + +S++   E
Sbjct: 196 SQKDKKDSKNSKKTNTEFLHTKNNPKKDLKRSKTSNDPISE 236



 Score = 31.2 bits (69), Expect = 1.1
 Identities = 40/193 (20%), Positives = 78/193 (40%), Gaps = 15/193 (7%)

Query: 91  KSWNKKFYDYEANMP-DRWGHSGYKELYPEEFETDSDQQDITNGKKTSPQVKSSTHESRK 149
           KSWN+K +      P  R  +   + L  +   T  D++ +  G+K  P  K   H  RK
Sbjct: 26  KSWNQKHFALTFPKPLQRGTNDKSRPLKSQITVTRHDKRKLEEGQK--PAHKWIRHSFRK 83

Query: 150 HKKSKKSHKKKQKKRSHKKQKKSKKEATDITADSSSEFSEETGASGTRKGKQPHKRKKKS 209
             +    +   +++   +    SK      T    +E+ +     G    K+  K+K  S
Sbjct: 84  ILQWPPIYTAAREQTPFRHLYTSK------THLKKAEYKKSKDEKGGTPLKKDSKKKGGS 137

Query: 210 RKKSLKKPALFLEAESNTSHSDDSASSSSEESEE-RDTKKTKRKKREKKAHTSVANNEIQ 268
              + +   +  E     + +D +   SS E+E+ + +K +     E +   +V+ N  Q
Sbjct: 138 YATNPESKQIVEEKTKRQNEADKTPLKSSHENEQSKKSKSSSETNPESQNSKTVSKNCSQ 197

Query: 269 E-----RTNKRTN 276
           +     + +K+TN
Sbjct: 198 KDKKDSKNSKKTN 210


>gi|56090620 NFKB activating protein-like [Homo sapiens]
          Length = 402

 Score = 66.2 bits (160), Expect = 3e-11
 Identities = 42/140 (30%), Positives = 72/140 (51%), Gaps = 8/140 (5%)

Query: 101 EANMPDRWGHSG-YKELYPEEFETDSDQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKK 159
           E   P+ WG S  + +L  +E     D++++T+ K +S     S   S +H+K K S  +
Sbjct: 130 ELGAPEVWGPSPKFPQLDSDEHTPVEDEEEVTHQKSSS-----SDSNSEEHRKKKTSRSR 184

Query: 160 KQKKRSHKKQKKSKKEATDITADSSSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPAL 219
            +KKR +K  K+  ++ +D  +DS+SE    + +   +K  +  K+KKK + K+ KK   
Sbjct: 185 NKKKRKNKSSKRKHRKYSD--SDSNSESDTNSDSDDDKKRVKAKKKKKKKKHKTKKKKNK 242

Query: 220 FLEAESNTSHSDDSASSSSE 239
             + ES+ S   DS    SE
Sbjct: 243 KTKKESSDSSCKDSEEDLSE 262



 Score = 50.8 bits (120), Expect = 1e-06
 Identities = 45/183 (24%), Positives = 85/183 (46%), Gaps = 16/183 (8%)

Query: 109 GHSGYKELYPEEFETDSDQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKK 168
           G+  ++  Y EE ++  D +   + ++   + +    E    +    S K  Q       
Sbjct: 93  GYRYHRHCYAEERQSAEDYEKEESHRQRRLKERERIGELGAPEVWGPSPKFPQLDSDEHT 152

Query: 169 QKKSKKEATDITADSSSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTS 228
             + ++E T   + SS   SEE     T + +   KRK KS K+  +K   + +++SN  
Sbjct: 153 PVEDEEEVTHQKSSSSDSNSEEHRKKKTSRSRNKKKRKNKSSKRKHRK---YSDSDSN-- 207

Query: 229 HSDDSASSSSEESEERDTKKTKRKKREKKAHTSVANNEIQERTNKRTNWKVATDERSAES 288
            S+   +S S++ ++R   K K+KK++KK  T       +++ NK+T  K ++D    +S
Sbjct: 208 -SESDTNSDSDDDKKR--VKAKKKKKKKKHKT-------KKKKNKKTK-KESSDSSCKDS 256

Query: 289 SED 291
            ED
Sbjct: 257 EED 259



 Score = 33.1 bits (74), Expect = 0.30
 Identities = 28/123 (22%), Positives = 56/123 (45%), Gaps = 22/123 (17%)

Query: 187 FSEETGASGTRKGKQPHKR---KKKSRKKSLKKPALF--------LEAESNTSHSDDS-- 233
           ++EE  ++   + ++ H++   K++ R   L  P ++        L+++ +T   D+   
Sbjct: 101 YAEERQSAEDYEKEESHRQRRLKERERIGELGAPEVWGPSPKFPQLDSDEHTPVEDEEEV 160

Query: 234 ----ASSSSEESEERDTKKTKRKKREKKAHTSVANNEIQERTNKRTNWKVATDERSAESS 289
               +SSS   SEE   KKT R + +KK       N+  +R +++ +   +  E    S 
Sbjct: 161 THQKSSSSDSNSEEHRKKKTSRSRNKKKR-----KNKSSKRKHRKYSDSDSNSESDTNSD 215

Query: 290 EDD 292
            DD
Sbjct: 216 SDD 218



 Score = 29.6 bits (65), Expect = 3.3
 Identities = 29/141 (20%), Positives = 53/141 (37%), Gaps = 3/141 (2%)

Query: 67  ESQRYYWRPKNEISGTLEDDFLKAKSWNKKFYDYEANMPDRWGHSGYKELYPE-EFETDS 125
           E +      K+  S +  ++  K K+   +      N   +  H  Y +     E +T+S
Sbjct: 155 EDEEEVTHQKSSSSDSNSEEHRKKKTSRSRNKKKRKNKSSKRKHRKYSDSDSNSESDTNS 214

Query: 126 DQQDITNGKKTSPQVKSSTHESRK--HKKSKKSHKKKQKKRSHKKQKKSKKEATDITADS 183
           D  D     K   + K   H+++K  +KK+KK       K S +   ++        AD+
Sbjct: 215 DSDDDKKRVKAKKKKKKKKHKTKKKKNKKTKKESSDSSCKDSEEDLSEATWMEQPNVADT 274

Query: 184 SSEFSEETGASGTRKGKQPHK 204
                 E     T + ++P K
Sbjct: 275 MDLIGPEAPIIHTSQDEKPLK 295


>gi|27734775 hypothetical protein LOC286499 [Homo sapiens]
          Length = 248

 Score = 63.2 bits (152), Expect = 3e-10
 Identities = 55/204 (26%), Positives = 85/204 (41%), Gaps = 17/204 (8%)

Query: 69  QRYYWRPK---NEISGTLEDDFLKAKSWNKKFYDYEANMPDRWGH----SGYKELYPEEF 121
           Q Y  RP+    E+   LE+     K+ +K   ++E  M + W      S  K L   E 
Sbjct: 31  QDYLNRPRPTWEEVKKQLENK----KTGSKALAEFEEKMNENWKKELEKSREKLLSGNES 86

Query: 122 ETDSDQQDITNGKKTS-PQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDIT 180
            +   ++     KK+      SS+ +S       +  +KKQ KR  KK+ +S K +   T
Sbjct: 87  SSKKRERKKKRKKKSCRSSSSSSSSDSSSSSSDSEDEEKKQGKRRKKKKNRSYKSSQSST 146

Query: 181 ADSSSEFSE-----ETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSAS 235
            +S SE  E     +     T K K      KK +K       L  E+ S + + +D  +
Sbjct: 147 HESESESKESVKKKKKSKDETEKEKDVRSLSKKRKKSYPDDKPLSSESSSESDYEEDVQA 206

Query: 236 SSSEESEERDTKKTKRKKREKKAH 259
                 EER+  K K KK++KK H
Sbjct: 207 KKKRRCEEREQAKEKVKKKKKKQH 230



 Score = 56.6 bits (135), Expect = 3e-08
 Identities = 41/146 (28%), Positives = 67/146 (45%), Gaps = 16/146 (10%)

Query: 146 ESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITADSSSEFSEETGASGTRKGKQPHKR 205
           E +K  ++KK+  K   +   K  +  KKE          E S E   SG     +  +R
Sbjct: 43  EVKKQLENKKTGSKALAEFEEKMNENWKKEL---------EKSREKLLSGNESSSKKRER 93

Query: 206 KKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEERDTKKTKRKKREKKAHTSVANN 265
           KKK +KKS +       + S++S SD S+SSS  E EE+   K ++KK+ +   +S ++ 
Sbjct: 94  KKKRKKKSCR-------SSSSSSSSDSSSSSSDSEDEEKKQGKRRKKKKNRSYKSSQSST 146

Query: 266 EIQERTNKRTNWKVATDERSAESSED 291
              E  +K +  K    +   E  +D
Sbjct: 147 HESESESKESVKKKKKSKDETEKEKD 172



 Score = 35.0 bits (79), Expect = 0.078
 Identities = 41/160 (25%), Positives = 64/160 (40%), Gaps = 18/160 (11%)

Query: 32  KIRELEKQMEDAYRGTKRKMLPSSSSRMRSDGFDEESQRYYWRPKNEI-------SGTLE 84
           K RE +K+ +     +      S SS   SD  DEE ++   R K +        S T E
Sbjct: 89  KKRERKKKRKKKSCRSSSSSSSSDSSSSSSDSEDEEKKQGKRRKKKKNRSYKSSQSSTHE 148

Query: 85  DDFLKAKSWNKKFYDYEANMPDRWGHS---GYKELYPE------EFETDSDQQDITNGKK 135
            +    +S  KK    +    ++   S     K+ YP+      E  ++SD ++    KK
Sbjct: 149 SESESKESVKKKKKSKDETEKEKDVRSLSKKRKKSYPDDKPLSSESSSESDYEEDVQAKK 208

Query: 136 TSPQVKSSTHESRKHKKSKKSHKKKQKKRSHK--KQKKSK 173
                +    + +  KK KK HKK  KK+  K     KS+
Sbjct: 209 KRRCEEREQAKEKVKKKKKKQHKKHSKKKKKKSGSSHKSR 248


>gi|91206454 hypothetical protein LOC257415 isoform 2 [Homo sapiens]
          Length = 237

 Score = 58.9 bits (141), Expect = 5e-09
 Identities = 61/219 (27%), Positives = 94/219 (42%), Gaps = 33/219 (15%)

Query: 69  QRYYWRPK---NEISGTLEDDFLKAKSWNKKFYDYEANMPDRWGHSGYKE----LYPEEF 121
           Q Y  RP+    E+   LE    K K  +K   ++E  M + W     K     L   E 
Sbjct: 21  QDYLNRPRPTWEEVKEQLE----KKKKGSKALAEFEEKMNENWKKELEKHREKLLSGSES 76

Query: 122 ETDSDQQDITNGKKT---------SPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKS 172
            +   Q+     KK+         S    SS+ +S    K +   +KK+K RSHK  + S
Sbjct: 77  SSKKRQRKKKEKKKSGRYSSSSSSSSDSSSSSSDSEDEDKKQGKRRKKKKNRSHKSSESS 136

Query: 173 KKEATDITADSSSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDD 232
             E    + DS  +  ++    GT K K      KK +  S  KP L  E+ S + + ++
Sbjct: 137 MSETESDSKDSLKK--KKKSKDGTEKEKDIKGLSKKRKMYSEDKP-LSSESLSESEYIEE 193

Query: 233 SASSSSEESEERD--TKKTKRKK--------REKKAHTS 261
             +   + SEER+  T+KTK+KK        ++KKA +S
Sbjct: 194 VRAKKKKSSEEREKATEKTKKKKKHKKHSKKKKKKAASS 232



 Score = 51.2 bits (121), Expect = 1e-06
 Identities = 40/144 (27%), Positives = 67/144 (46%), Gaps = 5/144 (3%)

Query: 146 ESRKHKKSKKS-HKKKQKKRSHKKQKKSKKEATDITADSSSEFSEETGASGTRKGKQPHK 204
           E  KH++   S  +   KKR  KK++K K      ++ SSS+ S  +  S     KQ  +
Sbjct: 62  ELEKHREKLLSGSESSSKKRQRKKKEKKKSGRYSSSSSSSSDSSSSSSDSEDEDKKQGKR 121

Query: 205 RKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESE-ERDTKKTKRKKR---EKKAHT 260
           RKKK  +      +   E ES++  S      S + +E E+D K   +K++   E K  +
Sbjct: 122 RKKKKNRSHKSSESSMSETESDSKDSLKKKKKSKDGTEKEKDIKGLSKKRKMYSEDKPLS 181

Query: 261 SVANNEIQERTNKRTNWKVATDER 284
           S + +E +     R   K +++ER
Sbjct: 182 SESLSESEYIEEVRAKKKKSSEER 205



 Score = 50.8 bits (120), Expect = 1e-06
 Identities = 39/159 (24%), Positives = 73/159 (45%), Gaps = 9/159 (5%)

Query: 134 KKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITADSSSEFSEETGA 193
           + + P ++   +  R   +  K   +K+KK S  K     +E  +       E   E   
Sbjct: 14  QSSGPTIQDYLNRPRPTWEEVKEQLEKKKKGS--KALAEFEEKMNENWKKELEKHREKLL 71

Query: 194 SGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEERDTKKTKRKK 253
           SG+    +  +RKKK +KKS +       + S++S SD S+SSS  E E++   K +RKK
Sbjct: 72  SGSESSSKKRQRKKKEKKKSGRY------SSSSSSSSDSSSSSSDSEDEDKKQGK-RRKK 124

Query: 254 REKKAHTSVANNEIQERTNKRTNWKVATDERSAESSEDD 292
           ++ ++H S  ++  +  ++ + + K     +     E D
Sbjct: 125 KKNRSHKSSESSMSETESDSKDSLKKKKKSKDGTEKEKD 163



 Score = 44.3 bits (103), Expect = 1e-04
 Identities = 47/191 (24%), Positives = 76/191 (39%), Gaps = 15/191 (7%)

Query: 25  QEESDMWKIRELEKQMEDAYRGTKRKMLPSSSSRMRSDGFDEESQRYYWRPKNEISGTLE 84
           ++ ++ WK +ELEK  E    G++     SS  R R     ++S RY        S +  
Sbjct: 53  EKMNENWK-KELEKHREKLLSGSES----SSKKRQRKKKEKKKSGRY------SSSSSSS 101

Query: 85  DDFLKAKSWNKKFYDYEANMPDRWGHSGYKELYPEEFETDSDQQDITNGKKTSPQVKSST 144
            D   + S ++     +     +  +  +K       ET+SD +D    KK S   K  T
Sbjct: 102 SDSSSSSSDSEDEDKKQGKRRKKKKNRSHKSSESSMSETESDSKDSLKKKKKS---KDGT 158

Query: 145 HESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITADSSSEFSEETGASGTRKGKQPHK 204
            + +  K   K  K   + +    +  S+ E  +       + SEE     T K K+  K
Sbjct: 159 EKEKDIKGLSKKRKMYSEDKPLSSESLSESEYIEEVRAKKKKSSEER-EKATEKTKKKKK 217

Query: 205 RKKKSRKKSLK 215
            KK S+KK  K
Sbjct: 218 HKKHSKKKKKK 228


>gi|91206456 hypothetical protein LOC257415 isoform 1 [Homo sapiens]
          Length = 247

 Score = 58.9 bits (141), Expect = 5e-09
 Identities = 61/219 (27%), Positives = 94/219 (42%), Gaps = 33/219 (15%)

Query: 69  QRYYWRPK---NEISGTLEDDFLKAKSWNKKFYDYEANMPDRWGHSGYKE----LYPEEF 121
           Q Y  RP+    E+   LE    K K  +K   ++E  M + W     K     L   E 
Sbjct: 31  QDYLNRPRPTWEEVKEQLE----KKKKGSKALAEFEEKMNENWKKELEKHREKLLSGSES 86

Query: 122 ETDSDQQDITNGKKT---------SPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKS 172
            +   Q+     KK+         S    SS+ +S    K +   +KK+K RSHK  + S
Sbjct: 87  SSKKRQRKKKEKKKSGRYSSSSSSSSDSSSSSSDSEDEDKKQGKRRKKKKNRSHKSSESS 146

Query: 173 KKEATDITADSSSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDD 232
             E    + DS  +  ++    GT K K      KK +  S  KP L  E+ S + + ++
Sbjct: 147 MSETESDSKDSLKK--KKKSKDGTEKEKDIKGLSKKRKMYSEDKP-LSSESLSESEYIEE 203

Query: 233 SASSSSEESEERD--TKKTKRKK--------REKKAHTS 261
             +   + SEER+  T+KTK+KK        ++KKA +S
Sbjct: 204 VRAKKKKSSEEREKATEKTKKKKKHKKHSKKKKKKAASS 242



 Score = 51.2 bits (121), Expect = 1e-06
 Identities = 40/144 (27%), Positives = 67/144 (46%), Gaps = 5/144 (3%)

Query: 146 ESRKHKKSKKS-HKKKQKKRSHKKQKKSKKEATDITADSSSEFSEETGASGTRKGKQPHK 204
           E  KH++   S  +   KKR  KK++K K      ++ SSS+ S  +  S     KQ  +
Sbjct: 72  ELEKHREKLLSGSESSSKKRQRKKKEKKKSGRYSSSSSSSSDSSSSSSDSEDEDKKQGKR 131

Query: 205 RKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESE-ERDTKKTKRKKR---EKKAHT 260
           RKKK  +      +   E ES++  S      S + +E E+D K   +K++   E K  +
Sbjct: 132 RKKKKNRSHKSSESSMSETESDSKDSLKKKKKSKDGTEKEKDIKGLSKKRKMYSEDKPLS 191

Query: 261 SVANNEIQERTNKRTNWKVATDER 284
           S + +E +     R   K +++ER
Sbjct: 192 SESLSESEYIEEVRAKKKKSSEER 215



 Score = 50.8 bits (120), Expect = 1e-06
 Identities = 39/159 (24%), Positives = 73/159 (45%), Gaps = 9/159 (5%)

Query: 134 KKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITADSSSEFSEETGA 193
           + + P ++   +  R   +  K   +K+KK S  K     +E  +       E   E   
Sbjct: 24  QSSGPTIQDYLNRPRPTWEEVKEQLEKKKKGS--KALAEFEEKMNENWKKELEKHREKLL 81

Query: 194 SGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEERDTKKTKRKK 253
           SG+    +  +RKKK +KKS +       + S++S SD S+SSS  E E++   K +RKK
Sbjct: 82  SGSESSSKKRQRKKKEKKKSGRY------SSSSSSSSDSSSSSSDSEDEDKKQGK-RRKK 134

Query: 254 REKKAHTSVANNEIQERTNKRTNWKVATDERSAESSEDD 292
           ++ ++H S  ++  +  ++ + + K     +     E D
Sbjct: 135 KKNRSHKSSESSMSETESDSKDSLKKKKKSKDGTEKEKD 173



 Score = 44.3 bits (103), Expect = 1e-04
 Identities = 47/191 (24%), Positives = 76/191 (39%), Gaps = 15/191 (7%)

Query: 25  QEESDMWKIRELEKQMEDAYRGTKRKMLPSSSSRMRSDGFDEESQRYYWRPKNEISGTLE 84
           ++ ++ WK +ELEK  E    G++     SS  R R     ++S RY        S +  
Sbjct: 63  EKMNENWK-KELEKHREKLLSGSES----SSKKRQRKKKEKKKSGRY------SSSSSSS 111

Query: 85  DDFLKAKSWNKKFYDYEANMPDRWGHSGYKELYPEEFETDSDQQDITNGKKTSPQVKSST 144
            D   + S ++     +     +  +  +K       ET+SD +D    KK S   K  T
Sbjct: 112 SDSSSSSSDSEDEDKKQGKRRKKKKNRSHKSSESSMSETESDSKDSLKKKKKS---KDGT 168

Query: 145 HESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITADSSSEFSEETGASGTRKGKQPHK 204
            + +  K   K  K   + +    +  S+ E  +       + SEE     T K K+  K
Sbjct: 169 EKEKDIKGLSKKRKMYSEDKPLSSESLSESEYIEEVRAKKKKSSEER-EKATEKTKKKKK 227

Query: 205 RKKKSRKKSLK 215
            KK S+KK  K
Sbjct: 228 HKKHSKKKKKK 238


>gi|4557509 cylicin 2 [Homo sapiens]
          Length = 348

 Score = 58.2 bits (139), Expect = 9e-09
 Identities = 64/252 (25%), Positives = 99/252 (39%), Gaps = 31/252 (12%)

Query: 30  MWKIRELEKQME--DAYRGTKRKMLP--------SSSSRMRSDGFDEESQRYYWRPKNEI 79
           +W  R L +  E    Y   +R+ L         S ++ +   G D+ +Q+     ++E+
Sbjct: 75  LWMYRSLMRISERPSVYLAARRQPLKPTRTVEVDSKAAEIGKKGEDKTTQKDTTDSESEL 134

Query: 80  SGTLEDDFLKAKSWNK-KFYDYEANMPDRWG----HSGYKELYPEEFETDSDQQDITNGK 134
               +D   K K   K K    +A    + G      G       E E    ++D    K
Sbjct: 135 KQGKKDS-KKGKDIEKGKEEKLDAKKDSKKGKKDAEKGKDSATESEDEKGGAKKDNKKDK 193

Query: 135 KTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITADSSSEFSEETGAS 194
           K S + K S  ES    + +K   +K  K+  K  KK K  A ++ A  + E  +E G  
Sbjct: 194 KDSNKGKDSATES----EGEKGGTEKDSKKGKKDSKKGKDSAIELQAVKADEKKDEDGKK 249

Query: 195 GTRKGKQPHKRKK-----KSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEERDTKKT 249
              KG +    KK     K  KK  KKP+      S  S S D     S++   +D KK 
Sbjct: 250 DANKGDESKDAKKDAKEIKKGKKDKKKPS------STDSDSKDDVKKESKKDATKDAKKV 303

Query: 250 KRKKREKKAHTS 261
            +K  EK++  S
Sbjct: 304 AKKDTEKESADS 315



 Score = 52.0 bits (123), Expect = 6e-07
 Identities = 38/174 (21%), Positives = 79/174 (45%), Gaps = 10/174 (5%)

Query: 128 QDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITADSSSEF 187
           +DI  GK+     K  + + +K  +  K    + +      +K +KK+  D      S  
Sbjct: 145 KDIEKGKEEKLDAKKDSKKGKKDAEKGKDSATESEDEKGGAKKDNKKDKKDSNKGKDSAT 204

Query: 188 SEETGASGTRK-GKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEERDT 246
             E    GT K  K+  K  KK +  +++  A+  + + +     D+      +  ++D 
Sbjct: 205 ESEGEKGGTEKDSKKGKKDSKKGKDSAIELQAVKADEKKDEDGKKDANKGDESKDAKKDA 264

Query: 247 KKTKRKKREKKAHTSV---ANNEIQERTNK---RTNWKVA---TDERSAESSED 291
           K+ K+ K++KK  +S    + +++++ + K   +   KVA   T++ SA+S +D
Sbjct: 265 KEIKKGKKDKKKPSSTDSDSKDDVKKESKKDATKDAKKVAKKDTEKESADSKKD 318



 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 50/248 (20%), Positives = 100/248 (40%), Gaps = 41/248 (16%)

Query: 18  TDAHNKIQE-ESDMWKIRELEKQMEDAYRGTKRKMLPSSSSRMRSDGFDEESQRYYWRPK 76
           TD+ +++++ + D  K +++EK  E+     K        +    D   E         +
Sbjct: 128 TDSESELKQGKKDSKKGKDIEKGKEEKLDAKKDSKKGKKDAEKGKDSATES--------E 179

Query: 77  NEISGTLEDDFLKAKSWNKKFYDYEANMPDRWGHSGYKELYPEEFETDSD----QQDITN 132
           +E  G  +D+    K  NK             G     E   E+  T+ D    ++D   
Sbjct: 180 DEKGGAKKDNKKDKKDSNK-------------GKDSATESEGEKGGTEKDSKKGKKDSKK 226

Query: 133 GKKTSPQVKSSTHESRKHKKSKKSHKK-------KQKKRSHKKQKKSKKEATDITADSSS 185
           GK ++ ++++   + +K +  KK   K       K+  +  KK KK KK+ +   +DS  
Sbjct: 227 GKDSAIELQAVKADEKKDEDGKKDANKGDESKDAKKDAKEIKKGKKDKKKPSSTDSDSKD 286

Query: 186 EFSEETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEERD 245
           +  +E+    T+  K+  K+  +      KK A          ++   A   ++++ ++D
Sbjct: 287 DVKKESKKDATKDAKKVAKKDTEKESADSKKDA--------KKNAKKDAKKDAKKNAKKD 338

Query: 246 TKKTKRKK 253
            KK  +KK
Sbjct: 339 EKKDAKKK 346


>gi|239754909 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 245

 Score = 56.2 bits (134), Expect = 3e-08
 Identities = 33/145 (22%), Positives = 64/145 (44%), Gaps = 1/145 (0%)

Query: 146 ESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITADSSSEFSEETGASGTRKGKQPHKR 205
           ES + K+ ++  K+K+++   +K+++ KKE          E  +       ++G++  KR
Sbjct: 56  ESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEKEKR 115

Query: 206 KKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEERDTKKTKRKKREKKAHTSVANN 265
           KKK +K+  +      E E       +       + EER+ K+ +RK+R+K+    V   
Sbjct: 116 KKKEKKERGRTSKEGKERERKEERKREERKERERKKEERE-KERERKERKKRERKQVGEK 174

Query: 266 EIQERTNKRTNWKVATDERSAESSE 290
           E + +  +R   K     R     E
Sbjct: 175 EEERKEKERKERKKRERNRKERKKE 199



 Score = 54.7 bits (130), Expect = 1e-07
 Identities = 35/173 (20%), Positives = 78/173 (45%), Gaps = 4/173 (2%)

Query: 122 ETDSDQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQKK-RSHKKQKKSKKEATDIT 180
           E +S+++     ++   + +    +  + KK KK  +KK+++ R  ++++K  KE  +  
Sbjct: 54  ERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEKE 113

Query: 181 ADSSSEFSEE--TGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSS 238
                E  E   T   G  + ++  +++++ +++  KK     E E       +      
Sbjct: 114 KRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERKERKKRERKQVGE 173

Query: 239 EESEERDTKKTKRKKREKKAHTSVANNEIQERTNKRTNWKVATDERSAESSED 291
           +E E ++ ++ +RKKRE+         E +ER  ++   K   +ER  E  +D
Sbjct: 174 KEEERKEKERKERKKRERNRKERKKERERKERRERKKERK-KKEERKKERQKD 225



 Score = 53.5 bits (127), Expect = 2e-07
 Identities = 51/247 (20%), Positives = 99/247 (40%), Gaps = 52/247 (21%)

Query: 32  KIRELEKQMEDAYRGTKRKMLPSSSSRMRSDGFDEESQRYYWRPKNEISGTLEDDFLKAK 91
           +IRE E+++E    G K +                ES+R   R + E          K K
Sbjct: 37  EIREREREIETRKEGKKER----------------ESERKKERRERE----------KRK 70

Query: 92  SWNKKFYDYEANMPDRWGHSGYKELYPEEFETDSDQQDITNGKKTSPQVKSSTHESRKHK 151
              +K    E    ++ G    +E   ++   + + ++    +K   + K      R  K
Sbjct: 71  REREKERKRERGKKEKKGERKKEERERKKRRREKENKE--GEEKEKRKKKEKKERGRTSK 128

Query: 152 KSKKSHKKKQKKRSHKKQKKSKKEATDITADSSSEFSEETGASGTRKGKQPHKRKKKSRK 211
           + K+  +K+++KR  +K+++ KKE      +   E  E       + G++  +RK+K RK
Sbjct: 129 EGKERERKEERKREERKERERKKE----EREKERERKERKKRERKQVGEKEEERKEKERK 184

Query: 212 KSLKKPALFLEAESNTSHSDDSASSSSEESEERDTKKTKRKKREKKAHTSVANNEIQERT 271
           +  K+             +        E  E R+ KK ++KK E+K          + + 
Sbjct: 185 ERKKR-----------ERNRKERKKERERKERRERKKERKKKEERKK---------ERQK 224

Query: 272 NKRTNWK 278
           +++TNW+
Sbjct: 225 DRQTNWR 231



 Score = 50.1 bits (118), Expect = 2e-06
 Identities = 36/175 (20%), Positives = 71/175 (40%), Gaps = 3/175 (1%)

Query: 119 EEFETDSDQQDITNGKKTSPQVKSSTHESRKHKKS-KKSHKKKQKKRSHKKQKKSKKEAT 177
           E  E +  +++    +K     K    E +K ++  KK  ++K+ K   +K+K+ KKE  
Sbjct: 62  ERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKK 121

Query: 178 DITADSSSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSS 237
           +    S      E      R+ ++  +RKK+ R+K  ++              ++     
Sbjct: 122 ERGRTSKEGKERERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKE- 180

Query: 238 SEESEERDTKKTKRKKREKKAHTSVANNEIQERTNKRTNWKVATDERSAESSEDD 292
            +E +ER  ++  RK+R+K+          +ER  K    K    +R     E +
Sbjct: 181 -KERKERKKRERNRKERKKERERKERRERKKERKKKEERKKERQKDRQTNWREKE 234



 Score = 46.2 bits (108), Expect = 3e-05
 Identities = 35/149 (23%), Positives = 69/149 (46%), Gaps = 16/149 (10%)

Query: 146 ESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITADSSSEFSEETGASGTRKGKQPHKR 205
           E+RK  K ++  ++K+++R  +K+K+ +++          E   E G    +  ++  +R
Sbjct: 46  ETRKEGKKERESERKKERREREKRKREREK----------ERKRERGKKEKKGERKKEER 95

Query: 206 KKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEER----DTKKTKRKKREKKAHTS 261
           ++K R++  K+     E E            +S+E +ER    + K+ +RK+RE+K    
Sbjct: 96  ERKKRRRE-KENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEER 154

Query: 262 VANNEIQERTNKRTNWKVATDERSAESSE 290
               E +ER  KR   +V   E   +  E
Sbjct: 155 EKERERKER-KKRERKQVGEKEEERKEKE 182



 Score = 38.1 bits (87), Expect = 0.009
 Identities = 38/199 (19%), Positives = 85/199 (42%), Gaps = 10/199 (5%)

Query: 16  RHTDAHNKIQEESDMWKIRELEKQMEDAYRGTK--RKMLPSSSSRMRSDGFDEESQRYYW 73
           R ++   + +E     + RE E++ E   +  K  RK       + R +  ++E +    
Sbjct: 55  RESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEKEK 114

Query: 74  RPKNEISGTLEDDFLKAKSWNKKFYDYEANMPDRWGHSGYKELYPEEFETDSDQQDITNG 133
           R K E     ++    +K   ++    E    +R      KE    E E +  ++     
Sbjct: 115 RKKKE----KKERGRTSKEGKERERKEERKREERKERERKKE--EREKERERKERKKRER 168

Query: 134 KKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITADSSSEFSEETGA 193
           K+   + +    + RK +K ++ ++K++KK   +K+++ +K+      +   E  ++   
Sbjct: 169 KQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKKEERKKERQKDRQT 228

Query: 194 SGTRKGKQPHKRKKKSRKK 212
           +   + K+  KR++K RKK
Sbjct: 229 NW--REKERGKRERKERKK 245


>gi|239749449 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 275

 Score = 54.7 bits (130), Expect = 1e-07
 Identities = 38/147 (25%), Positives = 62/147 (42%), Gaps = 24/147 (16%)

Query: 146 ESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITADSSSEFSEETGASGTRKGKQPHKR 205
           E RK KK KK  ++KQ+ R  +K+KK +KE                     R+ KQ  +R
Sbjct: 93  ERRKRKKEKKKRERKQRGRRERKKKKERKERE-------------------RENKQRRER 133

Query: 206 KKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEERDTKKTK-RKKREKKAHTSVAN 264
           K+K R+K  ++     E +               + EER+ K+ + RK+R+K+       
Sbjct: 134 KRKKRRKKKRRK----ERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERR 189

Query: 265 NEIQERTNKRTNWKVATDERSAESSED 291
              +ER  +R   K    +R  +   D
Sbjct: 190 ERKKERKKERRKKKERKKDRKTDRQTD 216



 Score = 53.1 bits (126), Expect = 3e-07
 Identities = 34/173 (19%), Positives = 74/173 (42%), Gaps = 6/173 (3%)

Query: 120 EFETDSDQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDI 179
           +  T+      ++  K   Q +S   + R+ ++ +K  ++K++KR   K++K K++  + 
Sbjct: 12  KLNTELQMVSCSHISKPCTQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRER 71

Query: 180 TADSSSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSE 239
             +   +  E       R+ K+  KRKK+ +K+  K+               +      E
Sbjct: 72  GKERERKRKEREKQRKERREKERRKRKKEKKKRERKQ-----RGRRERKKKKERKERERE 126

Query: 240 ESEERDTKKTKRKKREKKAHTSVANNEIQERTNKRTNWKVATDERSAESSEDD 292
             + R+ K+ KR+K++++        E  +R  KR   K    E+  E +  +
Sbjct: 127 NKQRRERKRKKRRKKKRRKERK-REKERGKRERKRKKRKKEEREKKRERNRKE 178



 Score = 53.1 bits (126), Expect = 3e-07
 Identities = 34/156 (21%), Positives = 67/156 (42%), Gaps = 17/156 (10%)

Query: 134 KKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITADSSSEFSEETGA 193
           K+   + +      ++ +K KK  KK+++K+  ++++K KKE  +               
Sbjct: 78  KRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKE--------------- 122

Query: 194 SGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEERD-TKKTKRK 252
              R+ KQ  +RK+K R+K  ++     E E              E  ++R+  +K ++K
Sbjct: 123 -RERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKK 181

Query: 253 KREKKAHTSVANNEIQERTNKRTNWKVATDERSAES 288
           +RE+K          +ER  K+   K    +R  +S
Sbjct: 182 ERERKERRERKKERKKERRKKKERKKDRKTDRQTDS 217



 Score = 47.8 bits (112), Expect = 1e-05
 Identities = 28/125 (22%), Positives = 56/125 (44%), Gaps = 28/125 (22%)

Query: 133 GKKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITADSSSEFSEETG 192
           G++   + K      R++K+ ++  +KK++K+  +K++K +KE                 
Sbjct: 110 GRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKE----------------- 152

Query: 193 ASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEERDTKKTKRK 252
                +GK+  KRKK+ +++  KK       E N                +++ KK +RK
Sbjct: 153 -----RGKRERKRKKRKKEEREKK------RERNRKERKKERERKERRERKKERKKERRK 201

Query: 253 KREKK 257
           K+E+K
Sbjct: 202 KKERK 206



 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 43/192 (22%), Positives = 76/192 (39%), Gaps = 13/192 (6%)

Query: 25  QEESDMWKIR-ELEKQMEDAYRGTKRKMLPSSSSRMRSDGFDEESQRYYWRPKNEISGTL 83
           Q ES+  K R E EK+  +  +  KR+       + +     +E +R     + +     
Sbjct: 31  QRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERR 90

Query: 84  EDDFLKAKSWNKKFYDYEANMPDRWGHSGYKELYPEEFETDSDQQDITNGKKTSPQVKSS 143
           E +  K K   KK    +    +R      KE   E  +    ++     KK   + K  
Sbjct: 91  EKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKRE 150

Query: 144 THESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITADSSSEFSEETGASGTRKGKQPH 203
               ++ +K KK  K++++K+  + +K+ KKE             E       +K ++  
Sbjct: 151 KERGKRERKRKKRKKEEREKKRERNRKERKKE------------RERKERRERKKERKKE 198

Query: 204 KRKKKSRKKSLK 215
           +RKKK RKK  K
Sbjct: 199 RRKKKERKKDRK 210



 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 33/180 (18%), Positives = 74/180 (41%), Gaps = 8/180 (4%)

Query: 120 EFETDSDQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDI 179
           E E   ++++    K+   + +      ++ KK KK  + K+++R  K+++K +KE  + 
Sbjct: 33  ESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREK 92

Query: 180 TADSSSEFSE--ETGASGTRKGKQPHKRK------KKSRKKSLKKPALFLEAESNTSHSD 231
                 +  +  E    G R+ K+  +RK      K+ R++  KK       +      +
Sbjct: 93  ERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKE 152

Query: 232 DSASSSSEESEERDTKKTKRKKREKKAHTSVANNEIQERTNKRTNWKVATDERSAESSED 291
                   +  +++ ++ KR++  K+        E +ER  +R   +    ER  +   D
Sbjct: 153 RGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKERKKDRKTD 212



 Score = 32.3 bits (72), Expect = 0.51
 Identities = 27/144 (18%), Positives = 57/144 (39%), Gaps = 3/144 (2%)

Query: 32  KIRELEKQMEDAYRGTKRKMLPSSSSRMRSDGFDEESQRYYWRPKNEISGTLEDDFLKAK 91
           K +E EKQ ++     +RK       R R      E ++   R + E       +  + K
Sbjct: 78  KRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKK 137

Query: 92  SWNKKFYDYEANMPDRWGHSGYKELYPEEFETDSDQQDITNGKKTSPQVKSSTHESRKHK 151
              KK         +R      ++   +E   + +++   N K+   + +      RK +
Sbjct: 138 RRKKKRRKERKREKERGKRERKRKKRKKE---EREKKRERNRKERKKERERKERRERKKE 194

Query: 152 KSKKSHKKKQKKRSHKKQKKSKKE 175
           + K+  KKK++K+  K  +++  +
Sbjct: 195 RKKERRKKKERKKDRKTDRQTDSQ 218


>gi|42560244 peptidylprolyl isomerase G [Homo sapiens]
          Length = 754

 Score = 54.7 bits (130), Expect = 1e-07
 Identities = 51/276 (18%), Positives = 112/276 (40%), Gaps = 24/276 (8%)

Query: 26  EESDMWKIRELEKQMEDAYRGTKRKMLPSSSSRMRSDGFDEESQRYYWRPKNEISGTLED 85
           +E D    R  EK+M    +G   + +     +  S G D+E  R   + K   S + E 
Sbjct: 471 KERDSKHNRNEEKRMRSRSKGRDHENVKEKEKQSDSKGKDQERSRSKEKSKQLESKSNEH 530

Query: 86  DFLKAKSWNKKFYDYEANMPDRWGHSGYKELYPEEFETDSDQQDITNGKKTSPQVKSSTH 145
           D  K+K  +++            G   Y          +S  ++ +  +  S +V+S TH
Sbjct: 531 DHSKSKEKDRRAQSRSRECDITKGKHSY----------NSRTRERSRSRDRSRRVRSRTH 580

Query: 146 ESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITADSS---------SEFSEETGASGT 196
           + R   +SK+ H+ ++++   + + +S++  T      S         S  SE   +   
Sbjct: 581 D-RDRSRSKEYHRYREQEYRRRGRSRSRERRTPPGRSRSKDRRRRRRDSRSSEREESQSR 639

Query: 197 RKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEERDTKKTKRKKREK 256
            K K  ++  K S +K   +    + ++S   +S +++     + ++    K K+  ++ 
Sbjct: 640 NKDKYRNQESKSSHRKENSESEKRMYSKSRDHNSSNNSREKKADRDQSPFSKIKQSSQDN 699

Query: 257 KAHTSVANNEIQERTNKRTNWKVATDERSAESSEDD 292
           +  +S+  N+  E+        V  + + ++  E+D
Sbjct: 700 ELKSSMLKNKEDEKIRS----SVEKENQKSKGQEND 731



 Score = 48.1 bits (113), Expect = 9e-06
 Identities = 33/137 (24%), Positives = 60/137 (43%), Gaps = 25/137 (18%)

Query: 155 KSHKKKQKKRSHKKQKKSKKEATDITADSSSEFSEETGASGT-------------RKGKQ 201
           KS  KK++K+ HK    S   ++D  + S S+ S ++  S +             RK  +
Sbjct: 180 KSKVKKEEKKRHKSSSSSSSSSSDSDSSSDSQSSSDSSDSESATEEKSKKRKKKHRKNSR 239

Query: 202 PHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSS------------EESEERDTKKT 249
            HK++KK RKKS K  +   EAE+  +    +                 +   + D K+ 
Sbjct: 240 KHKKEKKKRKKSKKSASSESEAENLEAQPQSTVRPEEIPPIPENRFLMRKSPPKADEKER 299

Query: 250 KRKKREKKAHTSVANNE 266
           K ++RE++   +  N++
Sbjct: 300 KNRERERERECNPPNSQ 316



 Score = 45.4 bits (106), Expect = 6e-05
 Identities = 34/99 (34%), Positives = 49/99 (49%), Gaps = 6/99 (6%)

Query: 154 KKSHKKKQKKRSHKKQKKSKKEATDITADSSSEFSEETGASGTRKGKQPHKRKKKSRKKS 213
           K   KK++KKR HK    S   ++D  + S S+ S ++  S +   ++  KRKKK RK S
Sbjct: 180 KSKVKKEEKKR-HKSSSSSSSSSSDSDSSSDSQSSSDSSDSESATEEKSKKRKKKHRKNS 238

Query: 214 LKKPALFLEAESNTSHSDDSASSSSE-ESEERDTKKTKR 251
            K      + +     S  SASS SE E+ E   + T R
Sbjct: 239 RKHK----KEKKKRKKSKKSASSESEAENLEAQPQSTVR 273



 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 29/89 (32%), Positives = 45/89 (50%), Gaps = 2/89 (2%)

Query: 202 PHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEERDTKKTKRKKREKKAHTS 261
           P  + KK  KK  K  +    + S++  S DS SSS     E  T++ K KKR+KK H  
Sbjct: 179 PKSKVKKEEKKRHKSSSSSSSSSSDSDSSSDSQSSSDSSDSESATEE-KSKKRKKK-HRK 236

Query: 262 VANNEIQERTNKRTNWKVATDERSAESSE 290
            +    +E+  ++ + K A+ E  AE+ E
Sbjct: 237 NSRKHKKEKKKRKKSKKSASSESEAENLE 265



 Score = 42.0 bits (97), Expect = 6e-04
 Identities = 37/123 (30%), Positives = 56/123 (45%), Gaps = 16/123 (13%)

Query: 123 TDSDQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKK--KQKKRSHKKQKKSKKEATDIT 180
           +DSD    +     S   +S+T E  K KK KK H+K  ++ K+  KK+KKSKK A   +
Sbjct: 202 SDSDSSSDSQSSSDSSDSESATEE--KSKKRKKKHRKNSRKHKKEKKKRKKSKKSA---S 256

Query: 181 ADSSSEFSEETGASGTRKGKQP---------HKRKKKSRKKSLKKPALFLEAESNTSHSD 231
           ++S +E  E    S  R  + P          K   K+ +K  K      E E N  +S 
Sbjct: 257 SESEAENLEAQPQSTVRPEEIPPIPENRFLMRKSPPKADEKERKNRERERERECNPPNSQ 316

Query: 232 DSA 234
            ++
Sbjct: 317 PAS 319



 Score = 39.7 bits (91), Expect = 0.003
 Identities = 57/300 (19%), Positives = 114/300 (38%), Gaps = 31/300 (10%)

Query: 18  TDAHNKIQEESDMWKIRELEKQMEDAYRGTKRKMLPSSSSRMRSDGFDEESQRYYWRPKN 77
           +D+ +  +E+S   K +  +   +      KRK    S+S   S+  + E+Q        
Sbjct: 217 SDSESATEEKSKKRKKKHRKNSRKHKKEKKKRKKSKKSASS-ESEAENLEAQPQSTVRPE 275

Query: 78  EISGTLEDDFLKAKSWNK----------KFYDYEANMPDRWGHSGYKELYPEEFETDSDQ 127
           EI    E+ FL  KS  K          +  + E N P+    S  + L      T S +
Sbjct: 276 EIPPIPENRFLMRKSPPKADEKERKNRERERERECNPPNSQPASYQRRL----LVTRSGR 331

Query: 128 QDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQ--------KKSKKEATDI 179
           +    G +       S    R  +     H +++ +R+ + +        K  K E  +I
Sbjct: 332 KIKGRGPRRYRTPSRSRSRDRFRRSETPPHWRQEMQRAQRMRVSSGERWIKGDKSELNEI 391

Query: 180 TADSSS-------EFSEETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDD 232
             +  S       + ++    S +   K   ++K K  K + K+  +   +E +  + + 
Sbjct: 392 KENQRSPVRVKERKITDHRNVSESPNRKNEKEKKVKDHKSNSKERDIRRNSEKDDKYKNK 451

Query: 233 SASSSSEESEERDTKKTKRKKREKKAHTSVANNEIQERTNKRTNWKVATDERSAESSEDD 292
               +  +S  +  +K+K K+R+ K H       ++ R+  R +  V   E+ ++S   D
Sbjct: 452 VKKRAKSKSRSKSKEKSKSKERDSK-HNRNEEKRMRSRSKGRDHENVKEKEKQSDSKGKD 510



 Score = 39.7 bits (91), Expect = 0.003
 Identities = 39/172 (22%), Positives = 70/172 (40%), Gaps = 15/172 (8%)

Query: 123 TDSDQQDITNGKKTSPQVKSSTHESRKHKKS--KKSHKKKQKKRSHKK------QKKSKK 174
           TD      +  +K   + K   H+S   ++   + S K  + K   KK      + KSK+
Sbjct: 407 TDHRNVSESPNRKNEKEKKVKDHKSNSKERDIRRNSEKDDKYKNKVKKRAKSKSRSKSKE 466

Query: 175 EATDITADSSSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSA 234
           ++     DS    +EE       KG+  H+  K+  K+S  K       +   S S + +
Sbjct: 467 KSKSKERDSKHNRNEEKRMRSRSKGRD-HENVKEKEKQSDSK-----GKDQERSRSKEKS 520

Query: 235 SSSSEESEERDTKKTKRKKREKKAHTSVAN-NEIQERTNKRTNWKVATDERS 285
                +S E D  K+K K R  ++ +   +  + +   N RT  +  + +RS
Sbjct: 521 KQLESKSNEHDHSKSKEKDRRAQSRSRECDITKGKHSYNSRTRERSRSRDRS 572



 Score = 38.1 bits (87), Expect = 0.009
 Identities = 47/270 (17%), Positives = 99/270 (36%), Gaps = 52/270 (19%)

Query: 69  QRYYWRPKNEISGTLEDDFLKAKSWNKKFYDYEANMPDRWGHSGYKELYPEEFETDSDQQ 128
           +R+    K+E++   E+     +   +K  D+  N+ +       KE   ++ +++S ++
Sbjct: 378 ERWIKGDKSELNEIKENQRSPVRVKERKITDHR-NVSESPNRKNEKEKKVKDHKSNSKER 436

Query: 129 DITNGKKTSPQVKSSTHESRKHK-KSKKSHKKKQKKRSHK-------------------- 167
           DI    +   + K+   +  K K +SK   K K K+R  K                    
Sbjct: 437 DIRRNSEKDDKYKNKVKKRAKSKSRSKSKEKSKSKERDSKHNRNEEKRMRSRSKGRDHEN 496

Query: 168 ---KQKKSKKEATDITADSSSEFSEETGASGTR-----------------------KGKQ 201
              K+K+S  +  D     S E S++  +                           KGK 
Sbjct: 497 VKEKEKQSDSKGKDQERSRSKEKSKQLESKSNEHDHSKSKEKDRRAQSRSRECDITKGKH 556

Query: 202 PHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEERDTKKTKRKKREKKAHTS 261
            +  + + R +S  +        S T   D S S       E++ ++ + + R ++  T 
Sbjct: 557 SYNSRTRERSRSRDRSR---RVRSRTHDRDRSRSKEYHRYREQEYRR-RGRSRSRERRTP 612

Query: 262 VANNEIQERTNKRTNWKVATDERSAESSED 291
              +  ++R  +R + + +  E S   ++D
Sbjct: 613 PGRSRSKDRRRRRRDSRSSEREESQSRNKD 642



 Score = 35.8 bits (81), Expect = 0.046
 Identities = 22/77 (28%), Positives = 36/77 (46%), Gaps = 2/77 (2%)

Query: 114 KELYPEEFETDSDQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSK 173
           K+ +     + S   D  +   +     SS  ES   +KSKK  +KK+ +++ +K KK K
Sbjct: 188 KKRHKSSSSSSSSSSDSDSSSDSQSSSDSSDSESATEEKSKK--RKKKHRKNSRKHKKEK 245

Query: 174 KEATDITADSSSEFSEE 190
           K+       +SSE   E
Sbjct: 246 KKRKKSKKSASSESEAE 262


>gi|40068059 CBF1 interacting corepressor [Homo sapiens]
          Length = 450

 Score = 54.3 bits (129), Expect = 1e-07
 Identities = 44/182 (24%), Positives = 81/182 (44%), Gaps = 7/182 (3%)

Query: 114 KELYPEEFETDSDQQ---DITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQK 170
           +E    E E D + +    +T  +K     K    E +K KK +K  K ++ +  HKK K
Sbjct: 197 QEYVASEGEEDPEVEFLKSLTTKQKQKLLRKLDRLEKKKKKKDRKKKKFQKSRSKHKKHK 256

Query: 171 KSKKEATDITADSSSEFSEETGAS-GTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSH 229
            S   ++  ++ SS+E SE +  S    K K+  ++K+K  K S    +   E + +   
Sbjct: 257 SSSSSSSSSSSSSSTETSESSSESESNNKEKKIQRKKRKKNKCSGHNNSDSEEKDKSKKR 316

Query: 230 SDDSASSSSEESEERDTKKTKRKKREKKAHTSV---ANNEIQERTNKRTNWKVATDERSA 286
                 SSS  + E+  +K +  K E     S    ++++ + RT+K +  K  ++ +  
Sbjct: 317 KLHEELSSSHHNREKAKEKPRFLKHESSREDSKWSHSDSDKKSRTHKHSPEKRGSERKEG 376

Query: 287 ES 288
            S
Sbjct: 377 SS 378



 Score = 45.4 bits (106), Expect = 6e-05
 Identities = 30/97 (30%), Positives = 48/97 (49%), Gaps = 2/97 (2%)

Query: 197 RKGKQPHKRKK--KSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEERDTKKTKRKKR 254
           +K K+  K+KK  KSR K  K  +    + S++S S    S SS ESE  + +K  ++K+
Sbjct: 234 KKKKKDRKKKKFQKSRSKHKKHKSSSSSSSSSSSSSSTETSESSSESESNNKEKKIQRKK 293

Query: 255 EKKAHTSVANNEIQERTNKRTNWKVATDERSAESSED 291
            KK   S  NN   E  +K    K+  +  S+  + +
Sbjct: 294 RKKNKCSGHNNSDSEEKDKSKKRKLHEELSSSHHNRE 330



 Score = 44.3 bits (103), Expect = 1e-04
 Identities = 56/261 (21%), Positives = 101/261 (38%), Gaps = 38/261 (14%)

Query: 12  RNVIRHTDAHNKIQEESDMWKIRELEKQMEDAYRGTKRKMLPSSSSRMRSDGFDEESQRY 71
           + ++R  D   K +++ D    R+ +K  +   +  K K   SSSS   S    E S   
Sbjct: 222 QKLLRKLDRLEKKKKKKD----RKKKKFQKSRSKHKKHKSSSSSSSSSSSSSSTETS--- 274

Query: 72  YWRPKNEISGTLEDDFLKAKSWNKKFYDYEANMPDRWGHSGYKELYPEEFETDSDQQDIT 131
                 E S   E +  + K   KK    + +     GH+           +DS+++D +
Sbjct: 275 ------ESSSESESNNKEKKIQRKKRKKNKCS-----GHNN----------SDSEEKDKS 313

Query: 132 NGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITADSSSEFSEET 191
             +K   ++ SS+H +R+  K K    K +  R   K   S  +    T   S E   + 
Sbjct: 314 KKRKLHEEL-SSSHHNREKAKEKPRFLKHESSREDSKWSHSDSDKKSRTHKHSPE---KR 369

Query: 192 GASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEER----DTK 247
           G+       + H R+++SR+   + P  + + E+      +     S  ++ R    D  
Sbjct: 370 GSERKEGSSRSHGREERSRRSRSRSPGSYKQRETRKRAQRNPGEEQSRRNDSRSHGTDLY 429

Query: 248 KTKRKKREKK--AHTSVANNE 266
           + ++  RE     HT V   E
Sbjct: 430 RGEKMYREHPGGTHTKVTQRE 450


>gi|239508778 PREDICTED: hypothetical protein, partial [Homo
           sapiens]
          Length = 123

 Score = 54.3 bits (129), Expect = 1e-07
 Identities = 29/103 (28%), Positives = 55/103 (53%), Gaps = 5/103 (4%)

Query: 119 EEFETDSDQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATD 178
           EE E +  +++    K+   + K  T E+ K K+ ++  KK+++KR  KK+++ ++E  +
Sbjct: 21  EEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEE 80

Query: 179 ITADSSSEFSEETGASGTRKGKQPHK-----RKKKSRKKSLKK 216
              +   E  +E G    +K K+  K     +KKK R+K+ KK
Sbjct: 81  EEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTKKK 123



 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 34/125 (27%), Positives = 56/125 (44%), Gaps = 15/125 (12%)

Query: 167 KKQKKSKKEATDITADSSSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAE-- 224
           KK+KK KKE  +   + + E  EE    G RK K+  KRK+K +KK  K+     E E  
Sbjct: 1   KKKKKKKKETEE--TEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEE 58

Query: 225 -----------SNTSHSDDSASSSSEESEERDTKKTKRKKREKKAHTSVANNEIQERTNK 273
                            ++      EE EE + ++ +R+K++KK        E +++  +
Sbjct: 59  EKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRR 118

Query: 274 RTNWK 278
           +T  K
Sbjct: 119 KTKKK 123



 Score = 53.9 bits (128), Expect = 2e-07
 Identities = 32/141 (22%), Positives = 63/141 (44%), Gaps = 20/141 (14%)

Query: 134 KKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITADSSSEFSEETGA 193
           KK   +    T E+ + ++ ++   K+++KR  K+++K KK+ T  T             
Sbjct: 3   KKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETE------------ 50

Query: 194 SGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEERDTKKTKRKK 253
              RK K+  ++K+K ++K  K      E E      ++      EE +E   ++ K+KK
Sbjct: 51  --KRKEKEEEEKKRKRKRKKKK------EEEEREEEEEEEEEEKEEEEKEEGRRRKKKKK 102

Query: 254 REKKAHTSVANNEIQERTNKR 274
           R +K        + + +T K+
Sbjct: 103 RRRKEEEEEKKKKRRRKTKKK 123



 Score = 51.6 bits (122), Expect = 8e-07
 Identities = 35/144 (24%), Positives = 66/144 (45%), Gaps = 28/144 (19%)

Query: 114 KELYPEEFETDSDQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSK 173
           KE    E   ++++++   GK+   + K    E  K KK+K++ K+K+K+   KK+K+ +
Sbjct: 8   KETEETEETEETEEEEEKEGKRKEKR-KEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKR 66

Query: 174 KEATDITADSSSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDS 233
           K+  +   +   E  EE       + K+  +R+KK +K+  K+                 
Sbjct: 67  KKKKE--EEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKE----------------- 107

Query: 234 ASSSSEESEERDTKKTKRKKREKK 257
                   EE + KK +R+K +KK
Sbjct: 108 --------EEEEKKKKRRRKTKKK 123



 Score = 34.3 bits (77), Expect = 0.13
 Identities = 17/88 (19%), Positives = 40/88 (45%), Gaps = 5/88 (5%)

Query: 205 RKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEERDTKKTKRKKREKKAHTSVAN 264
           +KKK +KK  ++       E+  +  ++      +E  +   K+ ++KK+ K+       
Sbjct: 1   KKKKKKKKETEETE-----ETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEK 55

Query: 265 NEIQERTNKRTNWKVATDERSAESSEDD 292
            E +++  ++   K   +ER  E  E++
Sbjct: 56  EEEEKKRKRKRKKKKEEEEREEEEEEEE 83


>gi|151301228 formin binding protein 3 [Homo sapiens]
          Length = 930

 Score = 54.3 bits (129), Expect = 1e-07
 Identities = 39/149 (26%), Positives = 68/149 (45%), Gaps = 20/149 (13%)

Query: 145 HESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITADSSS----EFSEETGA---SGTR 197
           HE + H    K H KK KK  H+K+ +S+  +     DS S    + SE   A   S + 
Sbjct: 775 HECQHHHSKNKKHSKKSKKH-HRKRSRSRSGSDSDDDDSHSKKKRQRSESRSASEHSSSA 833

Query: 198 KGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEERDTKKTKRKKREKK 257
           + ++ +K+ KK +KKS K+            H  DS  S +E  +++  K  + +K   +
Sbjct: 834 ESERSYKKSKKHKKKSKKR-----------RHKSDSPESDAEREKDKKEKDRESEKDRTR 882

Query: 258 AHTSVANNEIQERTNKRT-NWKVATDERS 285
             +   +   +++T K + NW  +  E S
Sbjct: 883 QRSESKHKSPKKKTGKDSGNWDTSGSELS 911



 Score = 54.3 bits (129), Expect = 1e-07
 Identities = 37/135 (27%), Positives = 62/135 (45%), Gaps = 16/135 (11%)

Query: 146 ESRKH-KKSKKSHKKKQKKRS---------HKKQKKSKKEATDITADSSSEFSEETGASG 195
           +++KH KKSKK H+K+ + RS         H K+K+ + E+   +  SSS  SE +    
Sbjct: 783 KNKKHSKKSKKHHRKRSRSRSGSDSDDDDSHSKKKRQRSESRSASEHSSSAESERS---- 838

Query: 196 TRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSD-DSASSSSEESEERDTKKTKRKKR 254
             K  + HK+K K R+     P    E E +    D +S    + +  E   K  K+K  
Sbjct: 839 -YKKSKKHKKKSKKRRHKSDSPESDAEREKDKKEKDRESEKDRTRQRSESKHKSPKKKTG 897

Query: 255 EKKAHTSVANNEIQE 269
           +   +   + +E+ E
Sbjct: 898 KDSGNWDTSGSELSE 912



 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 52/238 (21%), Positives = 98/238 (41%), Gaps = 26/238 (10%)

Query: 20  AHNKIQEESDMWKIRELEKQMEDAYRGTKRK------MLPSSSSRMRSDGFDEESQRYYW 73
           A N + E+++    RE E++ E+A R  KRK      ML  ++  +  D   E+ +  + 
Sbjct: 693 AFNSLLEKAEA---REREREKEEA-RKMKRKESAFKSMLKQAAPPIELDAVWEDIRERFV 748

Query: 74  RPKNEISGTLED-------DFLKAKSWNKKFYDYEANMPDRWGHSGYKELYPEEFETDSD 126
           +       TLE        DF+       + +  +     +     +++       +DSD
Sbjct: 749 KEPAFEDITLESERKRIFKDFMHVLEHECQHHHSKNKKHSKKSKKHHRKRSRSRSGSDSD 808

Query: 127 QQDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITADSSSE 186
             D  + KK       S  E     +S++S+KK +K +   K+++ K ++ +  A+   +
Sbjct: 809 DDDSHSKKKRQRSESRSASEHSSSAESERSYKKSKKHKKKSKKRRHKSDSPESDAEREKD 868

Query: 187 FSEETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEER 244
             E+   S   + +Q  + K KS KK   K         ++ + D S S  SE   E+
Sbjct: 869 KKEKDRESEKDRTRQRSESKHKSPKKKTGK---------DSGNWDTSGSELSEGELEK 917



 Score = 33.5 bits (75), Expect = 0.23
 Identities = 38/173 (21%), Positives = 66/173 (38%), Gaps = 38/173 (21%)

Query: 146 ESRKHKKSKKSHKKKQKK----RSHKKQKKSKKEATDITADSSSEFSEETG-----ASGT 196
           E+R+ ++ K+  +K ++K    +S  KQ     E   +  D    F +E           
Sbjct: 702 EAREREREKEEARKMKRKESAFKSMLKQAAPPIELDAVWEDIRERFVKEPAFEDITLESE 761

Query: 197 RKG-------------KQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEE 243
           RK              +  H + KK  KKS K             H   S S S  +S++
Sbjct: 762 RKRIFKDFMHVLEHECQHHHSKNKKHSKKSKKH------------HRKRSRSRSGSDSDD 809

Query: 244 RDTKKTKRKKREKKA----HTSVANNEIQERTNKRTNWKVATDERSAESSEDD 292
            D+   K+++R +      H+S A +E   + +K+   K       ++S E D
Sbjct: 810 DDSHSKKKRQRSESRSASEHSSSAESERSYKKSKKHKKKSKKRRHKSDSPESD 862



 Score = 33.5 bits (75), Expect = 0.23
 Identities = 20/91 (21%), Positives = 37/91 (40%)

Query: 201 QPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEERDTKKTKRKKREKKAHT 260
           Q H  K K   K  KK         + S SDD  S S ++ +  +++         ++  
Sbjct: 778 QHHHSKNKKHSKKSKKHHRKRSRSRSGSDSDDDDSHSKKKRQRSESRSASEHSSSAESER 837

Query: 261 SVANNEIQERTNKRTNWKVATDERSAESSED 291
           S   ++  ++ +K+   K  + E  AE  +D
Sbjct: 838 SYKKSKKHKKKSKKRRHKSDSPESDAEREKD 868


>gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo
           sapiens]
          Length = 434

 Score = 54.3 bits (129), Expect = 1e-07
 Identities = 40/190 (21%), Positives = 76/190 (40%), Gaps = 18/190 (9%)

Query: 116 LYPEEFETDSDQQDITNGKKTSPQV----------------KSSTHESRKHKKSKKSHKK 159
           L PE+   D D++   +    SP+                 + S +E RKH+   +S + 
Sbjct: 11  LAPEKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSRSRSKEG 70

Query: 160 KQKKRSHKKQKKSKKEATDITADSSSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPAL 219
           ++ +   K  KK K E  +    SS +  E   +S    G+  HKRK++   +       
Sbjct: 71  RRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSS--ENGEDRHKRKERKSSRGRSHSRS 128

Query: 220 FLEAESNTSHSDDSASSSSEESEERDTKKTKRKKREKKAHTSVANNEIQERTNKRTNWKV 279
                 + S S +   S S   E + ++   R++++ ++ +      I+ R+  R+  + 
Sbjct: 129 RSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRH 188

Query: 280 ATDERSAESS 289
            T  RS   S
Sbjct: 189 RTRSRSRTRS 198



 Score = 42.7 bits (99), Expect = 4e-04
 Identities = 32/134 (23%), Positives = 56/134 (41%), Gaps = 14/134 (10%)

Query: 135 KTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITADSSSEFSEETGAS 194
           K+S + KS  H  ++H   K   +    +    + K+ +++++   + S S   E    S
Sbjct: 78  KSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRERRHRS 137

Query: 195 GTRKGKQPHKR-------------KKKSRKKSL-KKPALFLEAESNTSHSDDSASSSSEE 240
            +R+ K+   R             +KKSR +S  +K  +   + S + H   + S S   
Sbjct: 138 RSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRTR 197

Query: 241 SEERDTKKTKRKKR 254
           S  RD KK   K R
Sbjct: 198 SRSRDRKKRIEKPR 211


>gi|50409756 SRp25 nuclear protein isoform 1 [Homo sapiens]
          Length = 360

 Score = 53.1 bits (126), Expect = 3e-07
 Identities = 31/111 (27%), Positives = 63/111 (56%), Gaps = 4/111 (3%)

Query: 151 KKSKKSHKKKQKKRSHKKQKKSKKEATDITADSSSEFSEETGASGTRKGKQP---HKRKK 207
           +K  +S  + + + S K++KKS+K+ +   + S+S+  + + A G      P    + K+
Sbjct: 130 RKRSRSRSRSRGRGSEKRKKKSRKDTSRNCSASTSQGRKASTAPGAEASPSPCITERSKQ 189

Query: 208 KSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEERDTK-KTKRKKREKK 257
           K+R+++    +    + S++S S  S+SSSS +  ++  K K KR+K++KK
Sbjct: 190 KARRRTRSSSSSSSSSSSSSSSSSSSSSSSSSDGRKKRGKYKDKRRKKKKK 240



 Score = 38.5 bits (88), Expect = 0.007
 Identities = 38/147 (25%), Positives = 62/147 (42%), Gaps = 19/147 (12%)

Query: 125 SDQQDITNGKKTSPQVKSSTHESRKHKKSKKSH---------KKKQKKRSHKKQKKSKKE 175
           S+++   + K TS    +ST + RK   +  +          + KQK R   +   S   
Sbjct: 144 SEKRKKKSRKDTSRNCSASTSQGRKASTAPGAEASPSPCITERSKQKARRRTRSSSSSSS 203

Query: 176 ATDITADSSSEFSEETGASGTRK-GKQPHKRKKKSRKKSLKK-------PALFLEAESNT 227
           ++  ++ SSS  S  + + G +K GK   KR+KK  KK  KK        A   + E+  
Sbjct: 204 SSSSSSSSSSSSSSSSSSDGRKKRGKYKDKRRKK--KKKRKKLKKKGKEKAEAQQVEALP 261

Query: 228 SHSDDSASSSSEESEERDTKKTKRKKR 254
             S D    S+ E E+      ++K R
Sbjct: 262 GPSLDQWHRSAGEEEDGPVLTDEQKSR 288



 Score = 38.1 bits (87), Expect = 0.009
 Identities = 31/152 (20%), Positives = 61/152 (40%), Gaps = 9/152 (5%)

Query: 123 TDSDQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITAD 182
           + S     ++   +S    SS    ++ K   K  KKK+K++  KK+ K K EA  + A 
Sbjct: 201 SSSSSSSSSSSSSSSSSSSSSDGRKKRGKYKDKRRKKKKKRKKLKKKGKEKAEAQQVEAL 260

Query: 183 SSSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESE 242
                 +   ++G  +       ++KSR +++K           T    D+  S   +  
Sbjct: 261 PGPSLDQWHRSAGEEEDGPVLTDEQKSRIQAMK---------PMTKEEWDARQSIIRKVV 311

Query: 243 ERDTKKTKRKKREKKAHTSVANNEIQERTNKR 274
           + +T +T+  K + +    +   E     NK+
Sbjct: 312 DPETGRTRLIKGDGEVLEEIVTKERHREINKQ 343


>gi|116089325 splicing factor, arginine/serine-rich 12 isoform a
           [Homo sapiens]
          Length = 624

 Score = 53.1 bits (126), Expect = 3e-07
 Identities = 36/170 (21%), Positives = 70/170 (41%), Gaps = 31/170 (18%)

Query: 122 ETDSDQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITA 181
           E +S + +   G ++    +S +  S K    +K  + K + RSH + +  +K+      
Sbjct: 294 EPESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDR----- 348

Query: 182 DSSSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEES 241
                          R+ K PHK++ KSR++   +         + SHS D    + E+ 
Sbjct: 349 ---------------RRSKSPHKKRSKSRERRKSR---------SRSHSRDKRKDTREKI 384

Query: 242 EERDTKKTKRKKREKKAHTSVANNEIQERTNKRTNWKVATDERSAESSED 291
           +E++  + K K REK+        + +ER   +   K    +R  +  +D
Sbjct: 385 KEKE--RVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKD 432



 Score = 52.0 bits (123), Expect = 6e-07
 Identities = 35/149 (23%), Positives = 68/149 (45%), Gaps = 11/149 (7%)

Query: 143 STHESRKHKKSKKSHKKKQKKRS-HKKQKKSKKEATDITADSSSEFSEETGASGTRKGKQ 201
           S H SR H +S+   K +++ +S HKK+ KS++     +   S +  ++T      K + 
Sbjct: 331 SKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERV 390

Query: 202 PHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEERDTKKTKRKKREKKAHTS 261
             K ++K R++  ++     E E     + D      ++  E+D +K K K RE++    
Sbjct: 391 KEKDREKEREREKER-----EKEKERGKNKDR-----DKEREKDREKDKEKDREREREKE 440

Query: 262 VANNEIQERTNKRTNWKVATDERSAESSE 290
              +  +E+  ++   K    +RS E  E
Sbjct: 441 HEKDRDKEKEKEQDKEKEREKDRSKEIDE 469



 Score = 49.7 bits (117), Expect = 3e-06
 Identities = 42/163 (25%), Positives = 73/163 (44%), Gaps = 8/163 (4%)

Query: 119 EEFETDSDQQDITNGKKTSPQVKSSTHE-SRKHKKSKKSHKKKQKKRSHKKQKKSKKEAT 177
           +E E D D++      K   + K  + E   K KK KKS    +   + ++ + S +E  
Sbjct: 439 KEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERR 498

Query: 178 DITADSSSEFSEETGASGTRKGKQ---PHKRKKKSRKKSLKKPALF--LEAESNTSHSDD 232
              + SSS  S  T  +  RK  +   P  R KK +K+  ++  +    E E +TS    
Sbjct: 499 RRRSRSSSR-SPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKS 557

Query: 233 SASSSSEESEERDTKKTKRKKREKKAHTSVANNEIQERTNKRT 275
           S     +E  E+++   K K+  K+  +SV + E+ ++   RT
Sbjct: 558 SNDRDGKEKLEKNSTSLKEKEHNKEPDSSV-SKEVDDKDAPRT 599



 Score = 45.4 bits (106), Expect = 6e-05
 Identities = 36/180 (20%), Positives = 73/180 (40%), Gaps = 13/180 (7%)

Query: 123 TDSDQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQK--------KSKK 174
           + S  +  ++ +  S Q      +S   K+SK   ++K + RSH + K        K K+
Sbjct: 329 SQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKE 388

Query: 175 EATDITADSSSEFSEETGASGTR-KGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDS 233
              +   +   E  +E      R K K   K ++K R+K  +K       + +    D  
Sbjct: 389 RVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKE 448

Query: 234 ASSSSEESEERDTKKTK----RKKREKKAHTSVANNEIQERTNKRTNWKVATDERSAESS 289
                ++ +ER+  ++K    ++K++KK+ T   +     R+   +  +     RS+  S
Sbjct: 449 KEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRS 508



 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 55/269 (20%), Positives = 103/269 (38%), Gaps = 36/269 (13%)

Query: 16  RHTDAHNKIQE-----ESDMWKIRELEKQMEDAYRGTKRKMLPSSSSRMRSDGFDEESQR 70
           +  D   KI+E     E D  K RE EK+ E      K K       + R    +++ +R
Sbjct: 376 KRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDRER 435

Query: 71  YYWRPKNEISGTLEDDFLKAKSWNKKFYDYEANMPDRWGHSGYKELYPEEFETDSDQQDI 130
                + E     + D  K K  +K+    +    DR      KE+  E+ + D   +  
Sbjct: 436 -----EREKEHEKDRDKEKEKEQDKE----KEREKDR-----SKEI-DEKRKKDKKSRTP 480

Query: 131 TNGKKTSPQVKSSTHESRKHK--------KSKKSHKKKQKKRSHKKQKKSKKEATDITAD 182
                 S + +SS+ E R+ +        ++ K+ K+K  +    + +  K +  +   D
Sbjct: 481 PRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERD 540

Query: 183 SSSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESE 242
             SE  E   ++  RK       K+K  K S         +     H+ +  SS S+E +
Sbjct: 541 HISERRERERSTSMRKSSNDRDGKEKLEKNS--------TSLKEKEHNKEPDSSVSKEVD 592

Query: 243 ERDTKKTKRKKREKKAHTSVANNEIQERT 271
           ++D  +T+  K +   +  +    +  +T
Sbjct: 593 DKDAPRTEENKIQHNGNCQLNEENLSTKT 621



 Score = 42.4 bits (98), Expect = 5e-04
 Identities = 34/181 (18%), Positives = 76/181 (41%), Gaps = 9/181 (4%)

Query: 119 EEFETDSDQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATD 178
           +E E + ++    +  K   + +    E  + ++ +K H+K + K   K+Q K K+   D
Sbjct: 403 KEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKD 462

Query: 179 ITADSSSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSS 238
            + +   +  ++  +    +     +R + S ++  ++ +        TS +    SS S
Sbjct: 463 RSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRS 522

Query: 239 EESEERDTKKTKRKK--------REKKAHTSVANNEIQERTNKRTNWKVATDERSAESSE 290
                R+ K  KR+K        RE++  TS+  +   +R  K    K +T  +  E ++
Sbjct: 523 PSPRSRNKKDKKREKERDHISERRERERSTSMRKSS-NDRDGKEKLEKNSTSLKEKEHNK 581

Query: 291 D 291
           +
Sbjct: 582 E 582



 Score = 37.0 bits (84), Expect = 0.021
 Identities = 31/187 (16%), Positives = 69/187 (36%), Gaps = 32/187 (17%)

Query: 105 PDRWGHSGYKELYPEEFETDSDQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKR 164
           P +  HS    + P E    +  +++    K   + +S    + + +  K + +K  + R
Sbjct: 250 PLKINHSNNAIVKPPEMTPQAAAKELEEVMKRVREAQSFISAAIEPESGKSNERKGGRSR 309

Query: 165 SHKKQKKSKKEATDITADSSSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAE 224
           SH + K                         +R   + H R+K+S+ K   +        
Sbjct: 310 SHTRSK-------------------------SRSSSKSHSRRKRSQSKHRSR-------S 337

Query: 225 SNTSHSDDSASSSSEESEERDTKKTKRKKREKKAHTSVANNEIQERTNKRTNWKVATDER 284
            N S S       S+   ++ +K  +R+K   ++H+     + +E+  ++   K    E+
Sbjct: 338 HNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREK 397

Query: 285 SAESSED 291
             E  ++
Sbjct: 398 EREREKE 404


>gi|104526627 triadin [Homo sapiens]
          Length = 729

 Score = 53.1 bits (126), Expect = 3e-07
 Identities = 37/155 (23%), Positives = 68/155 (43%), Gaps = 25/155 (16%)

Query: 119 EEFETDSDQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATD 178
           E+ E D   +D   G+   P ++       K +K +K  +K Q K +HK+++K K++  +
Sbjct: 117 EDEEDDDGDEDTDKGEIDEPPLRKKEIHKDKTEKQEKPERKIQTKVTHKEKEKGKEKVRE 176

Query: 179 ITADSSSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSS 238
                              K K   K   K + +  +KP      E+ T   +   + ++
Sbjct: 177 -------------------KEKPEKKATHKEKIEKKEKP------ETKTLAKEQKKAKTA 211

Query: 239 EESEERDTKKTKRKKREKKAHTSVANNEIQERTNK 273
           E+SEE+  K+ K  K+EK   T+    E+Q+  +K
Sbjct: 212 EKSEEKTKKEVKGGKQEKVKQTAAKVKEVQKTPSK 246



 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 59/266 (22%), Positives = 105/266 (39%), Gaps = 25/266 (9%)

Query: 37  EKQMEDAYRGTKRKMLPSSSSRMRSDGFDEESQRYYWRPKNEISGTLEDDFLKAKSWNKK 96
           E++ +   +G K++ +  ++++++      E Q+   +PK +     ++    +K   K 
Sbjct: 215 EEKTKKEVKGGKQEKVKQTAAKVK------EVQKTPSKPKEKED---KEKAAVSKHEQKD 265

Query: 97  FYDYEANMPDRWGHSGYKELYPEEFETDSDQQDITNGKKTSPQVKSSTHESRKHKKSKKS 156
            Y +   M D + H   K             +  +     SP ++    E +K +K   S
Sbjct: 266 QYAFCRYMIDIFVHGDLKPGQSPAIPPPLPTEQASRPTPASPALEEKEGEKKKAEKKVTS 325

Query: 157 HKKKQKKRSHKKQKKSKKEATDITADSSSEFSEETGASGTRKGKQPHKRKKKSRK---KS 213
             KK++K   KK K  K+ A D+      + SE     GT K       KK  +K   K 
Sbjct: 326 ETKKKEKEDIKK-KSEKETAIDVEKKEPGKASETK--QGTVKIAAQAAAKKDEKKEDSKK 382

Query: 214 LKKPALF-----LEAESNTSHSDDSASSSSEESEERDTK---KTKRKKREKKAHT--SVA 263
            KKPA        + E    H + + S   E S   D +   KT+R K E  A +     
Sbjct: 383 TKKPAEVEQPKGKKQEKKEKHVEPAKSPKKEHSVPSDKQVKAKTERAKEEIGAVSIKKAV 442

Query: 264 NNEIQERTNKRTNWKVATDERSAESS 289
             + +E+T K    ++  ++    SS
Sbjct: 443 PGKKEEKTTKTVEQEIRKEKSGKTSS 468



 Score = 39.3 bits (90), Expect = 0.004
 Identities = 29/130 (22%), Positives = 57/130 (43%), Gaps = 12/130 (9%)

Query: 122 ETDSDQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKK--QKKSKKEATDI 179
           E   D+ +     +   Q K +  E  K K+  +  +K +KK +HK+  +KK K E   +
Sbjct: 142 EIHKDKTEKQEKPERKIQTKVTHKEKEKGKEKVREKEKPEKKATHKEKIEKKEKPETKTL 201

Query: 180 TAD----SSSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSAS 235
             +     ++E SEE      + GKQ   ++  ++ K ++K        S     +D   
Sbjct: 202 AKEQKKAKTAEKSEEKTKKEVKGGKQEKVKQTAAKVKEVQK------TPSKPKEKEDKEK 255

Query: 236 SSSEESEERD 245
           ++  + E++D
Sbjct: 256 AAVSKHEQKD 265



 Score = 34.7 bits (78), Expect = 0.10
 Identities = 65/294 (22%), Positives = 110/294 (37%), Gaps = 47/294 (15%)

Query: 32  KIRELEKQMEDAYRGTKRKMLPSSSS-RMRSDGFDEE------SQRYYWRPKNEISGTLE 84
           K  + EK +E A    K   +PS    + +++   EE       +    + + + + T+E
Sbjct: 396 KQEKKEKHVEPAKSPKKEHSVPSDKQVKAKTERAKEEIGAVSIKKAVPGKKEEKTTKTVE 455

Query: 85  DDFLKAKSWNKKFYDYEANMPDRWGHSGYKELYP-----EEFETDSDQQDITNGK----- 134
            +  K KS         + + D+    G +E  P     +E ET  D++    GK     
Sbjct: 456 QEIRKEKSGKTS-----SILKDKEPIKGKEEKVPASLKEKEPETKKDEKMSKAGKEVKPK 510

Query: 135 ----------KTSPQVKSSTHE--SRKHKKSKKSHKKKQKKRSH-KKQKKSKKEATDITA 181
                     K  PQ+K       S K +  K+   K +K  SH K ++K  K+   +T 
Sbjct: 511 PPQLQGKKEEKPEPQIKKEAKPAISEKVQIHKQDIVKPEKTVSHGKPEEKVLKQVKAVTI 570

Query: 182 DSSSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEES 241
                  E+T      K  +  +R+  S K    KP     +E   S    +  S  E  
Sbjct: 571 -------EKTAKPKPTKKAEHREREPPSIKTDKPKPTPKGTSEVTESGKKKTEISEKESK 623

Query: 242 EERDTKKTKRKK----REKKAHTSVANNEIQERTNKRTNWKVATDERSAESSED 291
           E+ D K  + +K    +E     +V   E   R +K     V   +++ E +ED
Sbjct: 624 EKADMKHLREEKVSTRKESLQLHNVTKAEKPARVSKDVE-DVPASKKAKEGTED 676



 Score = 31.6 bits (70), Expect = 0.86
 Identities = 39/185 (21%), Positives = 78/185 (42%), Gaps = 20/185 (10%)

Query: 114 KELYPEEFETDSDQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSK 173
           K+   E+ +  S+++   + +K  P   S T +      ++ + KK +KK      + SK
Sbjct: 328 KKKEKEDIKKKSEKETAIDVEKKEPGKASETKQGTVKIAAQAAAKKDEKK------EDSK 381

Query: 174 KEATDITADSSSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPA-LFLEAESNTSHSDD 232
           K          +E  +  G    +K K  H    KS KK    P+   ++A++  +  + 
Sbjct: 382 K------TKKPAEVEQPKGKKQEKKEK--HVEPAKSPKKEHSVPSDKQVKAKTERAKEEI 433

Query: 233 SASSSSE----ESEERDTKKTKRK-KREKKAHTSVANNEIQERTNKRTNWKVATDERSAE 287
            A S  +    + EE+ TK  +++ ++EK   TS    + +    K      +  E+  E
Sbjct: 434 GAVSIKKAVPGKKEEKTTKTVEQEIRKEKSGKTSSILKDKEPIKGKEEKVPASLKEKEPE 493

Query: 288 SSEDD 292
           + +D+
Sbjct: 494 TKKDE 498


>gi|21040255 splicing factor, arginine/serine-rich 12 isoform b
           [Homo sapiens]
          Length = 508

 Score = 53.1 bits (126), Expect = 3e-07
 Identities = 36/170 (21%), Positives = 70/170 (41%), Gaps = 31/170 (18%)

Query: 122 ETDSDQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITA 181
           E +S + +   G ++    +S +  S K    +K  + K + RSH + +  +K+      
Sbjct: 178 EPESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDR----- 232

Query: 182 DSSSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEES 241
                          R+ K PHK++ KSR++   +         + SHS D    + E+ 
Sbjct: 233 ---------------RRSKSPHKKRSKSRERRKSR---------SRSHSRDKRKDTREKI 268

Query: 242 EERDTKKTKRKKREKKAHTSVANNEIQERTNKRTNWKVATDERSAESSED 291
           +E++  + K K REK+        + +ER   +   K    +R  +  +D
Sbjct: 269 KEKE--RVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKD 316



 Score = 52.0 bits (123), Expect = 6e-07
 Identities = 35/149 (23%), Positives = 68/149 (45%), Gaps = 11/149 (7%)

Query: 143 STHESRKHKKSKKSHKKKQKKRS-HKKQKKSKKEATDITADSSSEFSEETGASGTRKGKQ 201
           S H SR H +S+   K +++ +S HKK+ KS++     +   S +  ++T      K + 
Sbjct: 215 SKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERV 274

Query: 202 PHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEERDTKKTKRKKREKKAHTS 261
             K ++K R++  ++     E E     + D      ++  E+D +K K K RE++    
Sbjct: 275 KEKDREKEREREKER-----EKEKERGKNKDR-----DKEREKDREKDKEKDREREREKE 324

Query: 262 VANNEIQERTNKRTNWKVATDERSAESSE 290
              +  +E+  ++   K    +RS E  E
Sbjct: 325 HEKDRDKEKEKEQDKEKEREKDRSKEIDE 353



 Score = 49.7 bits (117), Expect = 3e-06
 Identities = 42/163 (25%), Positives = 73/163 (44%), Gaps = 8/163 (4%)

Query: 119 EEFETDSDQQDITNGKKTSPQVKSSTHE-SRKHKKSKKSHKKKQKKRSHKKQKKSKKEAT 177
           +E E D D++      K   + K  + E   K KK KKS    +   + ++ + S +E  
Sbjct: 323 KEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERR 382

Query: 178 DITADSSSEFSEETGASGTRKGKQ---PHKRKKKSRKKSLKKPALF--LEAESNTSHSDD 232
              + SSS  S  T  +  RK  +   P  R KK +K+  ++  +    E E +TS    
Sbjct: 383 RRRSRSSSR-SPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKS 441

Query: 233 SASSSSEESEERDTKKTKRKKREKKAHTSVANNEIQERTNKRT 275
           S     +E  E+++   K K+  K+  +SV + E+ ++   RT
Sbjct: 442 SNDRDGKEKLEKNSTSLKEKEHNKEPDSSV-SKEVDDKDAPRT 483



 Score = 45.4 bits (106), Expect = 6e-05
 Identities = 36/180 (20%), Positives = 73/180 (40%), Gaps = 13/180 (7%)

Query: 123 TDSDQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQK--------KSKK 174
           + S  +  ++ +  S Q      +S   K+SK   ++K + RSH + K        K K+
Sbjct: 213 SQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKE 272

Query: 175 EATDITADSSSEFSEETGASGTR-KGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDS 233
              +   +   E  +E      R K K   K ++K R+K  +K       + +    D  
Sbjct: 273 RVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKE 332

Query: 234 ASSSSEESEERDTKKTK----RKKREKKAHTSVANNEIQERTNKRTNWKVATDERSAESS 289
                ++ +ER+  ++K    ++K++KK+ T   +     R+   +  +     RS+  S
Sbjct: 333 KEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRS 392



 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 55/269 (20%), Positives = 103/269 (38%), Gaps = 36/269 (13%)

Query: 16  RHTDAHNKIQE-----ESDMWKIRELEKQMEDAYRGTKRKMLPSSSSRMRSDGFDEESQR 70
           +  D   KI+E     E D  K RE EK+ E      K K       + R    +++ +R
Sbjct: 260 KRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDRER 319

Query: 71  YYWRPKNEISGTLEDDFLKAKSWNKKFYDYEANMPDRWGHSGYKELYPEEFETDSDQQDI 130
                + E     + D  K K  +K+    +    DR      KE+  E+ + D   +  
Sbjct: 320 -----EREKEHEKDRDKEKEKEQDKE----KEREKDR-----SKEI-DEKRKKDKKSRTP 364

Query: 131 TNGKKTSPQVKSSTHESRKHK--------KSKKSHKKKQKKRSHKKQKKSKKEATDITAD 182
                 S + +SS+ E R+ +        ++ K+ K+K  +    + +  K +  +   D
Sbjct: 365 PRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERD 424

Query: 183 SSSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESE 242
             SE  E   ++  RK       K+K  K S         +     H+ +  SS S+E +
Sbjct: 425 HISERRERERSTSMRKSSNDRDGKEKLEKNS--------TSLKEKEHNKEPDSSVSKEVD 476

Query: 243 ERDTKKTKRKKREKKAHTSVANNEIQERT 271
           ++D  +T+  K +   +  +    +  +T
Sbjct: 477 DKDAPRTEENKIQHNGNCQLNEENLSTKT 505



 Score = 42.4 bits (98), Expect = 5e-04
 Identities = 34/181 (18%), Positives = 76/181 (41%), Gaps = 9/181 (4%)

Query: 119 EEFETDSDQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATD 178
           +E E + ++    +  K   + +    E  + ++ +K H+K + K   K+Q K K+   D
Sbjct: 287 KEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKD 346

Query: 179 ITADSSSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSS 238
            + +   +  ++  +    +     +R + S ++  ++ +        TS +    SS S
Sbjct: 347 RSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRS 406

Query: 239 EESEERDTKKTKRKK--------REKKAHTSVANNEIQERTNKRTNWKVATDERSAESSE 290
                R+ K  KR+K        RE++  TS+  +   +R  K    K +T  +  E ++
Sbjct: 407 PSPRSRNKKDKKREKERDHISERRERERSTSMRKSS-NDRDGKEKLEKNSTSLKEKEHNK 465

Query: 291 D 291
           +
Sbjct: 466 E 466



 Score = 37.0 bits (84), Expect = 0.021
 Identities = 31/187 (16%), Positives = 69/187 (36%), Gaps = 32/187 (17%)

Query: 105 PDRWGHSGYKELYPEEFETDSDQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKR 164
           P +  HS    + P E    +  +++    K   + +S    + + +  K + +K  + R
Sbjct: 134 PLKINHSNNAIVKPPEMTPQAAAKELEEVMKRVREAQSFISAAIEPESGKSNERKGGRSR 193

Query: 165 SHKKQKKSKKEATDITADSSSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAE 224
           SH + K                         +R   + H R+K+S+ K   +        
Sbjct: 194 SHTRSK-------------------------SRSSSKSHSRRKRSQSKHRSR-------S 221

Query: 225 SNTSHSDDSASSSSEESEERDTKKTKRKKREKKAHTSVANNEIQERTNKRTNWKVATDER 284
            N S S       S+   ++ +K  +R+K   ++H+     + +E+  ++   K    E+
Sbjct: 222 HNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREK 281

Query: 285 SAESSED 291
             E  ++
Sbjct: 282 EREREKE 288


>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
           sapiens]
          Length = 570

 Score = 52.4 bits (124), Expect = 5e-07
 Identities = 43/251 (17%), Positives = 109/251 (43%), Gaps = 21/251 (8%)

Query: 25  QEESDMW----KIRELEKQMEDAYRGTKRKMLPSSSSRMRSDGFDEESQRYYWRPKNEIS 80
           ++E  MW    KIRELE++M +  +  +++       ++R     +E +   WR + +I 
Sbjct: 334 RQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKI- 392

Query: 81  GTLEDDFLKAKSWNKKFYDYEANMPDRWGHSGYKELYPEEFETDSDQQDITNGKKTSPQV 140
                     +   +K  + E  M ++    G +E    E E +  +Q+    +K   Q 
Sbjct: 393 ----------REQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQE----EKMRRQE 438

Query: 141 KSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITADSSSEFSEETGASGTRKGK 200
           +    + +K ++ ++  +++++    +++K  ++E      ++  +  EE       K +
Sbjct: 439 EKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIR 498

Query: 201 QPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEERDTK--KTKRKKREKKA 258
           +  K+ ++  +K  ++  +  E E      ++      E+ +E++ K  + + K RE++ 
Sbjct: 499 EQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMREQEV 558

Query: 259 HTSVANNEIQE 269
                  ++QE
Sbjct: 559 RLRQQEEKMQE 569


>gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens]
          Length = 2454

 Score = 52.0 bits (123), Expect = 6e-07
 Identities = 71/309 (22%), Positives = 124/309 (40%), Gaps = 48/309 (15%)

Query: 18   TDAHNKIQEESDMWKIRELEKQMEDAYRGTKRKMLPSSSSRMRSDGFDEESQRYYWRPKN 77
            TD  +K+  +   +   E+ K  E      K K L + + +   DG  + ++++    K+
Sbjct: 880  TDGVDKLSGKEQSFTSLEVRKVAETK---EKSKHLKTKTCKKVQDGLSDIAEKFL--KKD 934

Query: 78   EISGTLEDDFLKAKSWN---KKFYDYEAN---MPDRW-GHSGYKELYPEEFETDSDQQDI 130
            +   T EDD  ++K      KK  D++     M  ++   S   E  PE  E     + I
Sbjct: 935  QSDETSEDDKKQSKKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLPEREEICHFPKGI 994

Query: 131  -------TNGKKTSPQVKSSTH--------------------ESRKHKKSKKSHKKKQKK 163
                   T+G+K S +++  T                     +S + KKSK     ++KK
Sbjct: 995  KQIKNGTTDGEKKSKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSEDKKSKNGAYGREKK 1054

Query: 164  RSHKKQKKSKKEATDITADSSSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEA 223
            R     K S+K     ++D+     +E G + + K     KR +   +++L       E 
Sbjct: 1055 RCKLLGKSSRKRQDCSSSDTEKYSMKEDGCNSSDKRL---KRIELRERRNLSSKRNTKEI 1111

Query: 224  ESNTSHSDDSASSSSEESEERDTKKTKRKKREKKAHTSVANNEIQERTNKRTNWKVATDE 283
            +S +S SD      +EES E + KK +R   +KKA           RT+ +      T  
Sbjct: 1112 QSGSSSSD------AEESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADITSS 1165

Query: 284  RSAESSEDD 292
             S++  +DD
Sbjct: 1166 SSSDIEDDD 1174



 Score = 42.7 bits (99), Expect = 4e-04
 Identities = 48/196 (24%), Positives = 75/196 (38%), Gaps = 33/196 (16%)

Query: 122  ETDSDQQDITNGKKTSPQVKS----STHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEAT 177
            E+DSD ++    +     ++     S  ES + KK+K    K+ K R+ +K      E +
Sbjct: 1285 ESDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDS 1344

Query: 178  DITADSSSEF---SEETGASGTRKGKQP--------HKRKKKSRK-------KSLKKPAL 219
            D      SE    SE+     TR  K+         +K+KKK R+        S  K   
Sbjct: 1345 DFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNS 1404

Query: 220  FLEAESNTSHSDDSASSSSEESEERDTKKTKRKKREK--------KAHTSVANNEIQERT 271
              E E      ++      EE +E D  K+  K R+K        K  T   N   +E  
Sbjct: 1405 EEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKGRKKIRKILKDDKLRTETQNALKEEEE 1464

Query: 272  NKRTNWKVATDERSAE 287
             ++   ++A  ER  E
Sbjct: 1465 RRK---RIAERERERE 1477



 Score = 42.0 bits (97), Expect = 6e-04
 Identities = 40/174 (22%), Positives = 79/174 (45%), Gaps = 18/174 (10%)

Query: 123 TDSDQQDITNGKKTSPQVKSSTHESRKHKKSKKS---------HKKKQKKRS--HKKQKK 171
           +D+D  +I    KT   +K+   +  K K+ +KS          K K  K S   KK+++
Sbjct: 712 SDTDINEIHTNHKTLYDLKTQAGKDDKGKRKRKSSTSGSDFDTKKGKSAKSSIISKKKRQ 771

Query: 172 SKKEATDITADSSSEFS--EETGASGTRKGKQPH-KRKKKSRKKSLKKPALFLEAESNTS 228
           ++ E+++  ++   E     + GA+ T K + P+ K    S  +   K  +  +   N  
Sbjct: 772 TQSESSNYDSELEKEIKSMSKIGAARTTKKRIPNTKDFDSSEDEKHSKKGMDNQGHKNLK 831

Query: 229 HSDDSASSSSEESEERDTKKTKRKKREKKAHTSVANNEIQERTNKRTNWKVATD 282
            S + +S  +E  +ER+T  +     +K   T++   E+++R  K+     +TD
Sbjct: 832 TSQEGSSDDAERKQERETFSSAEGTVDK--DTTIM--ELRDRLPKKQQASASTD 881



 Score = 41.6 bits (96), Expect = 8e-04
 Identities = 50/227 (22%), Positives = 86/227 (37%), Gaps = 26/227 (11%)

Query: 19   DAHNKIQEESDMWKIRELEKQMEDAYRGTKRKMLPSSSSRMRSDGFDEESQRYYWRPKNE 78
            +A N++  ESD     E  K+    +R  + K+  S       DG   E ++   +   E
Sbjct: 1277 EAKNQVNSESD--SDSEESKKPRYRHRLLRHKLTVS-------DGESGEEKKTKPKEHKE 1327

Query: 79   ISGTLEDDFLKAKSWNKKFYDYEANMPDRWGHSGYKELYPEEFETDSDQQDITNGKKTSP 138
            + G            N++    E +    +  SG  E   E  E++ +Q+  T   K + 
Sbjct: 1328 VKGR-----------NRRKVSSEDSEDSDFQESGVSE---EVSESEDEQRPRTRSAKKAE 1373

Query: 139  QVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITADSSSEFSEETGASGTRK 198
              ++    S K KK ++  K ++   S  K    ++E      +   E  EE        
Sbjct: 1374 LEENQ--RSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDD 1431

Query: 199  GKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEERD 245
             K P K +KK R K LK   L  E ++     ++     +E   ER+
Sbjct: 1432 SKSPGKGRKKIR-KILKDDKLRTETQNALKEEEERRKRIAERERERE 1477



 Score = 39.7 bits (91), Expect = 0.003
 Identities = 35/165 (21%), Positives = 70/165 (42%), Gaps = 14/165 (8%)

Query: 133  GKKTSPQVKSSTHESRKH--KKSKKSHKKKQKKRSHKKQKK---SKKEATDITADSSSEF 187
            GK +  +   S+ ++ K+  K+   +   K+ KR   ++++   SK+   +I + SSS  
Sbjct: 1060 GKSSRKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNLSSKRNTKEIQSGSSSSD 1119

Query: 188  SEETGASGTRKGKQPHKRKK---------KSRKKSLKKPALFLEAESNTSHSDDSASSSS 238
            +EE+     +K ++   +KK          S + S K+    + + S++   DD  +S  
Sbjct: 1120 AEESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADITSSSSSDIEDDDQNSIG 1179

Query: 239  EESEERDTKKTKRKKREKKAHTSVANNEIQERTNKRTNWKVATDE 283
            E S +    K   +     +HT    +   E  +K     V  D+
Sbjct: 1180 EGSSDEQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDDDD 1224



 Score = 39.3 bits (90), Expect = 0.004
 Identities = 62/308 (20%), Positives = 116/308 (37%), Gaps = 42/308 (13%)

Query: 26   EESDMWKIRELEKQMEDAYRGTKRKMLPSSSSRMRSDGFDEESQRYYWRPKNEIS-GTLE 84
            E++   K R   K+     +  KR  L +S+ R ++D     S       +N I  G+ +
Sbjct: 1125 EDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADITSSSSSDIEDDDQNSIGEGSSD 1184

Query: 85   DDFLKAKSWNKKFYDYEANMPDRWGHSGYKELYPEEFETDSDQQDITNG---KKTSPQVK 141
            +  +K  + N     +        G     +  P   + D D  D  N    K    ++K
Sbjct: 1185 EQKIKPVTENLVLSSHTGFCQSS-GDEALSKSVPVTVDDDDDDNDPENRIAKKMLLEEIK 1243

Query: 142  ---SSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITADSSSEFSEET------- 191
               SS  +     + ++  K+  K+       +  K   +  +DS SE S++        
Sbjct: 1244 ANLSSDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSESDSDSEESKKPRYRHRLL 1303

Query: 192  --------GASGTRKGKQPHKRKK---KSRKKSLKKPAL---FLEA--ESNTSHSDD--- 232
                    G SG  K  +P + K+   ++R+K   + +    F E+      S S+D   
Sbjct: 1304 RHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQR 1363

Query: 233  ----SASSSSEESEERDTKKTKRKKR----EKKAHTSVANNEIQERTNKRTNWKVATDER 284
                SA  +  E  +R  K+ K+++R    E  +  + +N+E +E   +    +   +E 
Sbjct: 1364 PRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEE 1423

Query: 285  SAESSEDD 292
              E   DD
Sbjct: 1424 EEEDENDD 1431



 Score = 38.9 bits (89), Expect = 0.005
 Identities = 47/189 (24%), Positives = 78/189 (41%), Gaps = 37/189 (19%)

Query: 119  EEFETDSDQQDITNGKK---TSPQVK--SSTHESRKHKKSKKSHKKKQKKRSHKKQKKSK 173
            ++    +D  D  +GK+   TS +V+  + T E  KH K+K   KK Q   S   +K  K
Sbjct: 874  QQASASTDGVDKLSGKEQSFTSLEVRKVAETKEKSKHLKTKTC-KKVQDGLSDIAEKFLK 932

Query: 174  KEATDITADSSSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDS 233
            K+ +D T++   + S++    GT + K+P   KKK            ++ E     S D 
Sbjct: 933  KDQSDETSEDDKKQSKK----GTEEKKKPSDFKKK-----------VIKMEQQYESSSDG 977

Query: 234  ASSSSEESE-----------ERDTKKTKRKKREKKAHTSVANNEIQERTNKRTNWKVATD 282
                 E  E           +  T   ++K ++ +  TS   +E+ +   K T       
Sbjct: 978  TEKLPEREEICHFPKGIKQIKNGTTDGEKKSKKIRDKTSKKKDELSDYAEKSTG-----K 1032

Query: 283  ERSAESSED 291
              S +SSED
Sbjct: 1033 GDSCDSSED 1041



 Score = 35.4 bits (80), Expect = 0.060
 Identities = 42/199 (21%), Positives = 82/199 (41%), Gaps = 30/199 (15%)

Query: 110 HSGYKELYPEEFETDSDQQDITNGKKTSPQVKSSTHESRKHKKSKKS--HKKKQKKRSHK 167
           H+ +K LY  + +T + + D    K+ S     S  +++K K +K S   KKK++ +S  
Sbjct: 720 HTNHKTLY--DLKTQAGKDDKGKRKRKS-STSGSDFDTKKGKSAKSSIISKKKRQTQSES 776

Query: 168 KQKKSKKE-------------ATDITADSSSEFSEETGASGTRKG--KQPHKRKKKSRKK 212
               S+ E              T     ++ +F        ++KG   Q HK  K S++ 
Sbjct: 777 SNYDSELEKEIKSMSKIGAARTTKKRIPNTKDFDSSEDEKHSKKGMDNQGHKNLKTSQEG 836

Query: 213 SLKKPALFLEAESNTSHSDDSASSSSEESEERDTKKTK-RKKREKKAHTSVANNEIQERT 271
           S         ++      +    SS+E + ++DT   + R +  KK   S + + + + +
Sbjct: 837 S---------SDDAERKQERETFSSAEGTVDKDTTIMELRDRLPKKQQASASTDGVDKLS 887

Query: 272 NKRTNWKVATDERSAESSE 290
            K  ++      + AE+ E
Sbjct: 888 GKEQSFTSLEVRKVAETKE 906



 Score = 28.9 bits (63), Expect = 5.6
 Identities = 31/168 (18%), Positives = 61/168 (36%), Gaps = 16/168 (9%)

Query: 12   RNVIRHTDAHNKIQEESDMWKIRELEKQMEDAYRGTKRKMLPSSSSRMRSDGFDEESQRY 71
            R V       +  QE     ++ E E +     R  K+  L             EE+QR 
Sbjct: 1334 RKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAEL-------------EENQRS 1380

Query: 72   YWRPKNEISGTLEDDFLKAKSWNKKFYDYEANMPDRWGHSGYKELYPEEFETDSDQQDIT 131
            Y + K      +++D   + S NK   + E    +       +E   EE E D  +    
Sbjct: 1381 YKQKKKRRRIKVQED---SSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGK 1437

Query: 132  NGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDI 179
              KK    +K     +      K+  +++++    +++++  +E  +I
Sbjct: 1438 GRKKIRKILKDDKLRTETQNALKEEEERRKRIAEREREREKLREVIEI 1485



 Score = 28.5 bits (62), Expect = 7.3
 Identities = 16/64 (25%), Positives = 33/64 (51%), Gaps = 7/64 (10%)

Query: 229 HSDDSASSSSEESEERDTKKTKRKKREKKAHTSVANNEIQERTNKRTNWKVATDERSAES 288
           +S +  +SSSE+S+   + ++KRK        S+    ++    K  + +   ++ S E+
Sbjct: 59  NSKEEGTSSSEKSKSSGSSRSKRK-------PSIVTKYVESDDEKPLDDETVNEDASNEN 111

Query: 289 SEDD 292
           SE+D
Sbjct: 112 SEND 115



 Score = 28.1 bits (61), Expect = 9.5
 Identities = 29/150 (19%), Positives = 64/150 (42%), Gaps = 12/150 (8%)

Query: 119 EEFETDSDQQDITNGK--------KTSPQVKSSTHESRKHKKSKKSHKKKQKKRS---HK 167
           ++F++  D++    G         KTS +  S   E ++ +++  S +    K +     
Sbjct: 807 KDFDSSEDEKHSKKGMDNQGHKNLKTSQEGSSDDAERKQERETFSSAEGTVDKDTTIMEL 866

Query: 168 KQKKSKKEATDITADSSSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNT 227
           + +  KK+    + D   + S +  +  + + ++  + K+KS+    K      +  S+ 
Sbjct: 867 RDRLPKKQQASASTDGVDKLSGKEQSFTSLEVRKVAETKEKSKHLKTKTCKKVQDGLSDI 926

Query: 228 SHSDDSASSSSEESEERDTKKTKRKKREKK 257
           +        S E SE+ D K++K+   EKK
Sbjct: 927 AEKFLKKDQSDETSED-DKKQSKKGTEEKK 955


>gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens]
          Length = 2492

 Score = 52.0 bits (123), Expect = 6e-07
 Identities = 71/309 (22%), Positives = 124/309 (40%), Gaps = 48/309 (15%)

Query: 18   TDAHNKIQEESDMWKIRELEKQMEDAYRGTKRKMLPSSSSRMRSDGFDEESQRYYWRPKN 77
            TD  +K+  +   +   E+ K  E      K K L + + +   DG  + ++++    K+
Sbjct: 918  TDGVDKLSGKEQSFTSLEVRKVAETK---EKSKHLKTKTCKKVQDGLSDIAEKFL--KKD 972

Query: 78   EISGTLEDDFLKAKSWN---KKFYDYEAN---MPDRW-GHSGYKELYPEEFETDSDQQDI 130
            +   T EDD  ++K      KK  D++     M  ++   S   E  PE  E     + I
Sbjct: 973  QSDETSEDDKKQSKKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLPEREEICHFPKGI 1032

Query: 131  -------TNGKKTSPQVKSSTH--------------------ESRKHKKSKKSHKKKQKK 163
                   T+G+K S +++  T                     +S + KKSK     ++KK
Sbjct: 1033 KQIKNGTTDGEKKSKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSEDKKSKNGAYGREKK 1092

Query: 164  RSHKKQKKSKKEATDITADSSSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEA 223
            R     K S+K     ++D+     +E G + + K     KR +   +++L       E 
Sbjct: 1093 RCKLLGKSSRKRQDCSSSDTEKYSMKEDGCNSSDKRL---KRIELRERRNLSSKRNTKEI 1149

Query: 224  ESNTSHSDDSASSSSEESEERDTKKTKRKKREKKAHTSVANNEIQERTNKRTNWKVATDE 283
            +S +S SD      +EES E + KK +R   +KKA           RT+ +      T  
Sbjct: 1150 QSGSSSSD------AEESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADITSS 1203

Query: 284  RSAESSEDD 292
             S++  +DD
Sbjct: 1204 SSSDIEDDD 1212



 Score = 42.7 bits (99), Expect = 4e-04
 Identities = 48/196 (24%), Positives = 75/196 (38%), Gaps = 33/196 (16%)

Query: 122  ETDSDQQDITNGKKTSPQVKS----STHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEAT 177
            E+DSD ++    +     ++     S  ES + KK+K    K+ K R+ +K      E +
Sbjct: 1323 ESDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDS 1382

Query: 178  DITADSSSEF---SEETGASGTRKGKQP--------HKRKKKSRK-------KSLKKPAL 219
            D      SE    SE+     TR  K+         +K+KKK R+        S  K   
Sbjct: 1383 DFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNS 1442

Query: 220  FLEAESNTSHSDDSASSSSEESEERDTKKTKRKKREK--------KAHTSVANNEIQERT 271
              E E      ++      EE +E D  K+  K R+K        K  T   N   +E  
Sbjct: 1443 EEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKGRKKIRKILKDDKLRTETQNALKEEEE 1502

Query: 272  NKRTNWKVATDERSAE 287
             ++   ++A  ER  E
Sbjct: 1503 RRK---RIAERERERE 1515



 Score = 42.0 bits (97), Expect = 6e-04
 Identities = 40/174 (22%), Positives = 79/174 (45%), Gaps = 18/174 (10%)

Query: 123 TDSDQQDITNGKKTSPQVKSSTHESRKHKKSKKS---------HKKKQKKRS--HKKQKK 171
           +D+D  +I    KT   +K+   +  K K+ +KS          K K  K S   KK+++
Sbjct: 750 SDTDINEIHTNHKTLYDLKTQAGKDDKGKRKRKSSTSGSDFDTKKGKSAKSSIISKKKRQ 809

Query: 172 SKKEATDITADSSSEFS--EETGASGTRKGKQPH-KRKKKSRKKSLKKPALFLEAESNTS 228
           ++ E+++  ++   E     + GA+ T K + P+ K    S  +   K  +  +   N  
Sbjct: 810 TQSESSNYDSELEKEIKSMSKIGAARTTKKRIPNTKDFDSSEDEKHSKKGMDNQGHKNLK 869

Query: 229 HSDDSASSSSEESEERDTKKTKRKKREKKAHTSVANNEIQERTNKRTNWKVATD 282
            S + +S  +E  +ER+T  +     +K   T++   E+++R  K+     +TD
Sbjct: 870 TSQEGSSDDAERKQERETFSSAEGTVDK--DTTIM--ELRDRLPKKQQASASTD 919



 Score = 41.6 bits (96), Expect = 8e-04
 Identities = 50/227 (22%), Positives = 86/227 (37%), Gaps = 26/227 (11%)

Query: 19   DAHNKIQEESDMWKIRELEKQMEDAYRGTKRKMLPSSSSRMRSDGFDEESQRYYWRPKNE 78
            +A N++  ESD     E  K+    +R  + K+  S       DG   E ++   +   E
Sbjct: 1315 EAKNQVNSESD--SDSEESKKPRYRHRLLRHKLTVS-------DGESGEEKKTKPKEHKE 1365

Query: 79   ISGTLEDDFLKAKSWNKKFYDYEANMPDRWGHSGYKELYPEEFETDSDQQDITNGKKTSP 138
            + G            N++    E +    +  SG  E   E  E++ +Q+  T   K + 
Sbjct: 1366 VKGR-----------NRRKVSSEDSEDSDFQESGVSE---EVSESEDEQRPRTRSAKKAE 1411

Query: 139  QVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITADSSSEFSEETGASGTRK 198
              ++    S K KK ++  K ++   S  K    ++E      +   E  EE        
Sbjct: 1412 LEENQ--RSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDD 1469

Query: 199  GKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEERD 245
             K P K +KK R K LK   L  E ++     ++     +E   ER+
Sbjct: 1470 SKSPGKGRKKIR-KILKDDKLRTETQNALKEEEERRKRIAERERERE 1515



 Score = 39.7 bits (91), Expect = 0.003
 Identities = 35/165 (21%), Positives = 70/165 (42%), Gaps = 14/165 (8%)

Query: 133  GKKTSPQVKSSTHESRKH--KKSKKSHKKKQKKRSHKKQKK---SKKEATDITADSSSEF 187
            GK +  +   S+ ++ K+  K+   +   K+ KR   ++++   SK+   +I + SSS  
Sbjct: 1098 GKSSRKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNLSSKRNTKEIQSGSSSSD 1157

Query: 188  SEETGASGTRKGKQPHKRKK---------KSRKKSLKKPALFLEAESNTSHSDDSASSSS 238
            +EE+     +K ++   +KK          S + S K+    + + S++   DD  +S  
Sbjct: 1158 AEESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADITSSSSSDIEDDDQNSIG 1217

Query: 239  EESEERDTKKTKRKKREKKAHTSVANNEIQERTNKRTNWKVATDE 283
            E S +    K   +     +HT    +   E  +K     V  D+
Sbjct: 1218 EGSSDEQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDDDD 1262



 Score = 39.3 bits (90), Expect = 0.004
 Identities = 62/308 (20%), Positives = 116/308 (37%), Gaps = 42/308 (13%)

Query: 26   EESDMWKIRELEKQMEDAYRGTKRKMLPSSSSRMRSDGFDEESQRYYWRPKNEIS-GTLE 84
            E++   K R   K+     +  KR  L +S+ R ++D     S       +N I  G+ +
Sbjct: 1163 EDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADITSSSSSDIEDDDQNSIGEGSSD 1222

Query: 85   DDFLKAKSWNKKFYDYEANMPDRWGHSGYKELYPEEFETDSDQQDITNG---KKTSPQVK 141
            +  +K  + N     +        G     +  P   + D D  D  N    K    ++K
Sbjct: 1223 EQKIKPVTENLVLSSHTGFCQSS-GDEALSKSVPVTVDDDDDDNDPENRIAKKMLLEEIK 1281

Query: 142  ---SSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITADSSSEFSEET------- 191
               SS  +     + ++  K+  K+       +  K   +  +DS SE S++        
Sbjct: 1282 ANLSSDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSESDSDSEESKKPRYRHRLL 1341

Query: 192  --------GASGTRKGKQPHKRKK---KSRKKSLKKPAL---FLEA--ESNTSHSDD--- 232
                    G SG  K  +P + K+   ++R+K   + +    F E+      S S+D   
Sbjct: 1342 RHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQR 1401

Query: 233  ----SASSSSEESEERDTKKTKRKKR----EKKAHTSVANNEIQERTNKRTNWKVATDER 284
                SA  +  E  +R  K+ K+++R    E  +  + +N+E +E   +    +   +E 
Sbjct: 1402 PRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEE 1461

Query: 285  SAESSEDD 292
              E   DD
Sbjct: 1462 EEEDENDD 1469



 Score = 38.9 bits (89), Expect = 0.005
 Identities = 47/189 (24%), Positives = 78/189 (41%), Gaps = 37/189 (19%)

Query: 119  EEFETDSDQQDITNGKK---TSPQVK--SSTHESRKHKKSKKSHKKKQKKRSHKKQKKSK 173
            ++    +D  D  +GK+   TS +V+  + T E  KH K+K   KK Q   S   +K  K
Sbjct: 912  QQASASTDGVDKLSGKEQSFTSLEVRKVAETKEKSKHLKTKTC-KKVQDGLSDIAEKFLK 970

Query: 174  KEATDITADSSSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDS 233
            K+ +D T++   + S++    GT + K+P   KKK            ++ E     S D 
Sbjct: 971  KDQSDETSEDDKKQSKK----GTEEKKKPSDFKKK-----------VIKMEQQYESSSDG 1015

Query: 234  ASSSSEESE-----------ERDTKKTKRKKREKKAHTSVANNEIQERTNKRTNWKVATD 282
                 E  E           +  T   ++K ++ +  TS   +E+ +   K T       
Sbjct: 1016 TEKLPEREEICHFPKGIKQIKNGTTDGEKKSKKIRDKTSKKKDELSDYAEKSTG-----K 1070

Query: 283  ERSAESSED 291
              S +SSED
Sbjct: 1071 GDSCDSSED 1079



 Score = 35.4 bits (80), Expect = 0.060
 Identities = 42/199 (21%), Positives = 82/199 (41%), Gaps = 30/199 (15%)

Query: 110 HSGYKELYPEEFETDSDQQDITNGKKTSPQVKSSTHESRKHKKSKKS--HKKKQKKRSHK 167
           H+ +K LY  + +T + + D    K+ S     S  +++K K +K S   KKK++ +S  
Sbjct: 758 HTNHKTLY--DLKTQAGKDDKGKRKRKS-STSGSDFDTKKGKSAKSSIISKKKRQTQSES 814

Query: 168 KQKKSKKE-------------ATDITADSSSEFSEETGASGTRKG--KQPHKRKKKSRKK 212
               S+ E              T     ++ +F        ++KG   Q HK  K S++ 
Sbjct: 815 SNYDSELEKEIKSMSKIGAARTTKKRIPNTKDFDSSEDEKHSKKGMDNQGHKNLKTSQEG 874

Query: 213 SLKKPALFLEAESNTSHSDDSASSSSEESEERDTKKTK-RKKREKKAHTSVANNEIQERT 271
           S         ++      +    SS+E + ++DT   + R +  KK   S + + + + +
Sbjct: 875 S---------SDDAERKQERETFSSAEGTVDKDTTIMELRDRLPKKQQASASTDGVDKLS 925

Query: 272 NKRTNWKVATDERSAESSE 290
            K  ++      + AE+ E
Sbjct: 926 GKEQSFTSLEVRKVAETKE 944



 Score = 28.9 bits (63), Expect = 5.6
 Identities = 31/168 (18%), Positives = 61/168 (36%), Gaps = 16/168 (9%)

Query: 12   RNVIRHTDAHNKIQEESDMWKIRELEKQMEDAYRGTKRKMLPSSSSRMRSDGFDEESQRY 71
            R V       +  QE     ++ E E +     R  K+  L             EE+QR 
Sbjct: 1372 RKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAEL-------------EENQRS 1418

Query: 72   YWRPKNEISGTLEDDFLKAKSWNKKFYDYEANMPDRWGHSGYKELYPEEFETDSDQQDIT 131
            Y + K      +++D   + S NK   + E    +       +E   EE E D  +    
Sbjct: 1419 YKQKKKRRRIKVQED---SSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGK 1475

Query: 132  NGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDI 179
              KK    +K     +      K+  +++++    +++++  +E  +I
Sbjct: 1476 GRKKIRKILKDDKLRTETQNALKEEEERRKRIAEREREREKLREVIEI 1523



 Score = 28.5 bits (62), Expect = 7.3
 Identities = 16/64 (25%), Positives = 33/64 (51%), Gaps = 7/64 (10%)

Query: 229 HSDDSASSSSEESEERDTKKTKRKKREKKAHTSVANNEIQERTNKRTNWKVATDERSAES 288
           +S +  +SSSE+S+   + ++KRK        S+    ++    K  + +   ++ S E+
Sbjct: 59  NSKEEGTSSSEKSKSSGSSRSKRK-------PSIVTKYVESDDEKPLDDETVNEDASNEN 111

Query: 289 SEDD 292
           SE+D
Sbjct: 112 SEND 115



 Score = 28.1 bits (61), Expect = 9.5
 Identities = 29/150 (19%), Positives = 64/150 (42%), Gaps = 12/150 (8%)

Query: 119 EEFETDSDQQDITNGK--------KTSPQVKSSTHESRKHKKSKKSHKKKQKKRS---HK 167
           ++F++  D++    G         KTS +  S   E ++ +++  S +    K +     
Sbjct: 845 KDFDSSEDEKHSKKGMDNQGHKNLKTSQEGSSDDAERKQERETFSSAEGTVDKDTTIMEL 904

Query: 168 KQKKSKKEATDITADSSSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNT 227
           + +  KK+    + D   + S +  +  + + ++  + K+KS+    K      +  S+ 
Sbjct: 905 RDRLPKKQQASASTDGVDKLSGKEQSFTSLEVRKVAETKEKSKHLKTKTCKKVQDGLSDI 964

Query: 228 SHSDDSASSSSEESEERDTKKTKRKKREKK 257
           +        S E SE+ D K++K+   EKK
Sbjct: 965 AEKFLKKDQSDETSED-DKKQSKKGTEEKK 993


>gi|21040326 SON DNA-binding protein isoform F [Homo sapiens]
          Length = 2426

 Score = 51.6 bits (122), Expect = 8e-07
 Identities = 44/197 (22%), Positives = 88/197 (44%), Gaps = 17/197 (8%)

Query: 102  ANMPDRWGHSGYKELYPEEFETDSDQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQ 161
            ++MP+R   S  +E   +++E     +D T+ K    + +    + +K   S +S  K+ 
Sbjct: 1773 SSMPERASESSSEE--KDDYEIFVKVKD-THEKSKKNKNRDKGEKEKKRDSSLRSRSKRS 1829

Query: 162  KKRSHKKQKK---SKKEATDITADSSSEFSEETGASGTRKGKQPHKRKKKSR-KKSLKKP 217
            K   HK +K+   S+  A   ++ S S  S+    S +R+ ++  + + KSR ++S+ K 
Sbjct: 1830 KSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKE 1889

Query: 218  ALFLEAESNTSHSDDSASSSSEESEERDTKKTKRKK-----REKKAHTSVANNEIQERTN 272
                + + +  H   S     + S  RD +KT R +     R  ++HT  +         
Sbjct: 1890 ----KRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSRSHTP-SRRRRSRSVG 1944

Query: 273  KRTNWKVATDERSAESS 289
            +R ++ ++   RS   S
Sbjct: 1945 RRRSFSISPSRRSRTPS 1961



 Score = 40.0 bits (92), Expect = 0.002
 Identities = 23/69 (33%), Positives = 38/69 (55%), Gaps = 10/69 (14%)

Query: 135 KTSPQVKSSTHESRKHK--KSKKSHKKKQKKRSHKKQKKSKKEAT--------DITADSS 184
           +T P  +  T +S+KHK  K+KK  KKK+K++ +K+Q +  +  T        D+ +DS 
Sbjct: 96  QTDPTDEIPTKKSKKHKKHKNKKKKKKKEKEKKYKRQPEESESKTKSHDDGNIDLESDSF 155

Query: 185 SEFSEETGA 193
            +F  E  A
Sbjct: 156 LKFDSEPSA 164



 Score = 37.4 bits (85), Expect = 0.016
 Identities = 35/180 (19%), Positives = 73/180 (40%), Gaps = 15/180 (8%)

Query: 77   NEISGTLEDD---FLKAKSWNKKFYDYEANMPDRWGHSGYKELYPEEFETDSDQQDITNG 133
            +E S   +DD   F+K K  ++K      +  ++    G KE   +       ++  ++ 
Sbjct: 1780 SESSSEEKDDYEIFVKVKDTHEK------SKKNKNRDKGEKEKKRDSSLRSRSKRSKSSE 1833

Query: 134  KKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITADSSSEFSEETGA 193
             K+  +   S   +RK     KSH+ + + RS  ++++    +   +    S   E+   
Sbjct: 1834 HKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKR 1893

Query: 194  SGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEERDTKKTKRKK 253
            S   + K   +++K+S  +  +K    + A S T       S S   S  R ++   R++
Sbjct: 1894 SPKHRSKSRERKRKRSSSRDNRKT---VRARSRT---PSRRSRSHTPSRRRRSRSVGRRR 1947



 Score = 33.1 bits (74), Expect = 0.30
 Identities = 19/127 (14%), Positives = 54/127 (42%)

Query: 147  SRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITADSSSEFSEETGASGTRKGKQPHKRK 206
            SR   + ++S  K+++KRS K + KS++     ++   +  +    +    +  + H   
Sbjct: 1876 SRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSRSHTPS 1935

Query: 207  KKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEERDTKKTKRKKREKKAHTSVANNE 266
            ++ R +S+ +   F  + S  S +    S +        +++++   R  +  +  +   
Sbjct: 1936 RRRRSRSVGRRRSFSISPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTP 1995

Query: 267  IQERTNK 273
             + R ++
Sbjct: 1996 SRRRRSR 2002



 Score = 28.1 bits (61), Expect = 9.5
 Identities = 19/69 (27%), Positives = 28/69 (40%), Gaps = 11/69 (15%)

Query: 168 KQKKSKKEATDITADSSSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPALFL----EA 223
           K+   K     +  D + E         T+K K+  K K K +KK  +K   +     E+
Sbjct: 84  KEGSRKSRCVSVQTDPTDEIP-------TKKSKKHKKHKNKKKKKKKEKEKKYKRQPEES 136

Query: 224 ESNTSHSDD 232
           ES T   DD
Sbjct: 137 ESKTKSHDD 145


>gi|21040314 SON DNA-binding protein isoform B [Homo sapiens]
          Length = 2303

 Score = 51.6 bits (122), Expect = 8e-07
 Identities = 44/197 (22%), Positives = 88/197 (44%), Gaps = 17/197 (8%)

Query: 102  ANMPDRWGHSGYKELYPEEFETDSDQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQ 161
            ++MP+R   S  +E   +++E     +D T+ K    + +    + +K   S +S  K+ 
Sbjct: 1773 SSMPERASESSSEE--KDDYEIFVKVKD-THEKSKKNKNRDKGEKEKKRDSSLRSRSKRS 1829

Query: 162  KKRSHKKQKK---SKKEATDITADSSSEFSEETGASGTRKGKQPHKRKKKSR-KKSLKKP 217
            K   HK +K+   S+  A   ++ S S  S+    S +R+ ++  + + KSR ++S+ K 
Sbjct: 1830 KSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKE 1889

Query: 218  ALFLEAESNTSHSDDSASSSSEESEERDTKKTKRKK-----REKKAHTSVANNEIQERTN 272
                + + +  H   S     + S  RD +KT R +     R  ++HT  +         
Sbjct: 1890 ----KRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSRSHTP-SRRRRSRSVG 1944

Query: 273  KRTNWKVATDERSAESS 289
            +R ++ ++   RS   S
Sbjct: 1945 RRRSFSISPSRRSRTPS 1961



 Score = 40.0 bits (92), Expect = 0.002
 Identities = 23/69 (33%), Positives = 38/69 (55%), Gaps = 10/69 (14%)

Query: 135 KTSPQVKSSTHESRKHK--KSKKSHKKKQKKRSHKKQKKSKKEAT--------DITADSS 184
           +T P  +  T +S+KHK  K+KK  KKK+K++ +K+Q +  +  T        D+ +DS 
Sbjct: 96  QTDPTDEIPTKKSKKHKKHKNKKKKKKKEKEKKYKRQPEESESKTKSHDDGNIDLESDSF 155

Query: 185 SEFSEETGA 193
            +F  E  A
Sbjct: 156 LKFDSEPSA 164



 Score = 37.4 bits (85), Expect = 0.016
 Identities = 35/180 (19%), Positives = 73/180 (40%), Gaps = 15/180 (8%)

Query: 77   NEISGTLEDD---FLKAKSWNKKFYDYEANMPDRWGHSGYKELYPEEFETDSDQQDITNG 133
            +E S   +DD   F+K K  ++K      +  ++    G KE   +       ++  ++ 
Sbjct: 1780 SESSSEEKDDYEIFVKVKDTHEK------SKKNKNRDKGEKEKKRDSSLRSRSKRSKSSE 1833

Query: 134  KKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITADSSSEFSEETGA 193
             K+  +   S   +RK     KSH+ + + RS  ++++    +   +    S   E+   
Sbjct: 1834 HKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKR 1893

Query: 194  SGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEERDTKKTKRKK 253
            S   + K   +++K+S  +  +K    + A S T       S S   S  R ++   R++
Sbjct: 1894 SPKHRSKSRERKRKRSSSRDNRKT---VRARSRT---PSRRSRSHTPSRRRRSRSVGRRR 1947



 Score = 33.1 bits (74), Expect = 0.30
 Identities = 19/127 (14%), Positives = 54/127 (42%)

Query: 147  SRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITADSSSEFSEETGASGTRKGKQPHKRK 206
            SR   + ++S  K+++KRS K + KS++     ++   +  +    +    +  + H   
Sbjct: 1876 SRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSRSHTPS 1935

Query: 207  KKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEERDTKKTKRKKREKKAHTSVANNE 266
            ++ R +S+ +   F  + S  S +    S +        +++++   R  +  +  +   
Sbjct: 1936 RRRRSRSVGRRRSFSISPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTP 1995

Query: 267  IQERTNK 273
             + R ++
Sbjct: 1996 SRRRRSR 2002



 Score = 28.1 bits (61), Expect = 9.5
 Identities = 19/69 (27%), Positives = 28/69 (40%), Gaps = 11/69 (15%)

Query: 168 KQKKSKKEATDITADSSSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPALFL----EA 223
           K+   K     +  D + E         T+K K+  K K K +KK  +K   +     E+
Sbjct: 84  KEGSRKSRCVSVQTDPTDEIP-------TKKSKKHKKHKNKKKKKKKEKEKKYKRQPEES 136

Query: 224 ESNTSHSDD 232
           ES T   DD
Sbjct: 137 ESKTKSHDD 145


>gi|38788333 remodeling and spacing factor 1 [Homo sapiens]
          Length = 1441

 Score = 51.2 bits (121), Expect = 1e-06
 Identities = 43/190 (22%), Positives = 92/190 (48%), Gaps = 17/190 (8%)

Query: 118  PEEFETDSDQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKR--SHKKQKKSKKE 175
            P+E E D    D ++    S +++   H SR  ++S++  +K  KK+     ++++S++ 
Sbjct: 1126 PDESEEDPPSNDDSDTDFCSRRLRR--HPSRPMRQSRRLRRKTPKKKYSDDDEEEESEEN 1183

Query: 176  ATDITADSSSEFSEETGASGTRKGKQPHKR--------KKKSRKKSLKKPALFLEAES-- 225
            + D  +D S +FS++   +  R+ ++  KR        +    +KSL++           
Sbjct: 1184 SRDSESDFSDDFSDDFVETRRRRSRRNQKRQINYKEDSESDGSQKSLRRGKEIRRVHKRR 1243

Query: 226  -NTSHSDDSASSSSEESEE--RDTKKTKRKKREKKAHTSVANNEIQERTNKRTNWKVATD 282
             ++S S++S  S + E +E  +++K++ RK+       S A+ E +E   K +  ++   
Sbjct: 1244 LSSSESEESYLSKNSEDDELAKESKRSVRKRGRSTDEYSEADEEEEEEEGKPSRKRLHRI 1303

Query: 283  ERSAESSEDD 292
            E   E S D+
Sbjct: 1304 ETDEEESCDN 1313



 Score = 43.1 bits (100), Expect = 3e-04
 Identities = 49/235 (20%), Positives = 93/235 (39%), Gaps = 43/235 (18%)

Query: 34   RELEKQMEDAYRGTKRKMLPSSSSRMRSDGFDEESQRYYWRPKNEISGTLEDDFLKAKSW 93
            R L +      R ++R    +   +   D  +EES+      +++ S    DDF++ +  
Sbjct: 1146 RRLRRHPSRPMRQSRRLRRKTPKKKYSDDDEEEESEENSRDSESDFSDDFSDDFVETRRR 1205

Query: 94   NKKFYDYEANMPDRWGHSGYKEL-YPEEFETDSDQQDITNGKKTSPQVK-----SSTHES 147
              +              +  +++ Y E+ E+D  Q+ +  GK+     K     S + ES
Sbjct: 1206 RSR-------------RNQKRQINYKEDSESDGSQKSLRRGKEIRRVHKRRLSSSESEES 1252

Query: 148  RKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITADSSSEFSEETGASGTRKGKQPHKRKK 207
               K S+     K+ KRS +K+ +S    TD  +++  E  EE G               
Sbjct: 1253 YLSKNSEDDELAKESKRSVRKRGRS----TDEYSEADEEEEEEEG--------------- 1293

Query: 208  KSRKKSLKKPALFLEAESNTSHSDDSASSSSEE-----SEERDTKKTKRKKREKK 257
            K  +K L +     E   + +H D +  +   +     SE+  TKK  R + +++
Sbjct: 1294 KPSRKRLHRIETDEEESCDNAHGDANQPARDSQPRVLPSEQESTKKPYRIESDEE 1348



 Score = 37.0 bits (84), Expect = 0.021
 Identities = 34/177 (19%), Positives = 68/177 (38%), Gaps = 17/177 (9%)

Query: 115 ELYPEEFETDSDQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKK 174
           +L PEE  T S+  +IT+ ++      +    SRK K        + + +  K +K+ +K
Sbjct: 709 KLVPEEETTASENTEITSERQKEGIKLTIRISSRKKKPDSPPKVLEPENKQEKTEKEEEK 768

Query: 175 EATDITADSSSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSA 234
                T   S   S  T      + ++  K++ +   +        +E ES      D  
Sbjct: 769 TNVGRTLRRSPRISRPTAKVAEIRDQKADKKRGEGEDE--------VEEESTALQKTDKK 820

Query: 235 SSSSEESEERDTKKTKRKKREKKAHTSVANNEIQERTNKRTNWKVATDERSAESSED 291
               +  ++ ++K +K K + K   T          +  R  WK ++++ S  S  +
Sbjct: 821 EILKKSEKDTNSKVSKVKPKGKVRWTG---------SRTRGRWKYSSNDESEGSGSE 868



 Score = 36.6 bits (83), Expect = 0.027
 Identities = 31/135 (22%), Positives = 63/135 (46%), Gaps = 19/135 (14%)

Query: 124 DSDQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITADS 183
           +S QQD  N  + SP +     E  + KK +++ K++++K S K   KS+++  D+   S
Sbjct: 216 NSSQQD--NSSRESPSL-----EDEETKKEEETPKQEEQKESEKM--KSEEQPMDLENRS 266

Query: 184 SSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEE 243
           ++   EET            K++K+  K+ +K P +    +    + +        +S +
Sbjct: 267 TANVLEETTV----------KKEKEDEKELVKLPVIVKLEKPLPENEEKKIIKEESDSFK 316

Query: 244 RDTKKTKRKKREKKA 258
            + K  K + +E +A
Sbjct: 317 ENVKPIKVEVKECRA 331



 Score = 30.4 bits (67), Expect = 1.9
 Identities = 42/194 (21%), Positives = 63/194 (32%), Gaps = 45/194 (23%)

Query: 143  STHESRKHKKSKKSHKKKQKKRSHKKQK------------------KSKKEATDITADSS 184
            S  +  K K SKKS     ++RS + +K                     KEA        
Sbjct: 990  SEDQEEKKKDSKKSKANLLERRSTRTRKCISYRFDEFDEAIDEAIEDDIKEADGGGVGRG 1049

Query: 185  SEFSEETGASGT----------RKGKQPHK-----RKKKSRKKSLKKPALFLEAESNTSH 229
             + S  TG  G           ++ K+P +     RKK+ R   L   +   E ES    
Sbjct: 1050 KDISTITGHRGKDISTILDEERKENKRPQRAAAARRKKRRRLNDLDSDSNLDEEESEDEF 1109

Query: 230  ------------SDDSASSSSEESEERDTKKTKRKKREKKAHTSVANNEIQERTNKRTNW 277
                        SD++   S E+    D   T    R  + H S    + +    K    
Sbjct: 1110 KISDGSQDEFVVSDENPDESEEDPPSNDDSDTDFCSRRLRRHPSRPMRQSRRLRRKTPKK 1169

Query: 278  KVATDERSAESSED 291
            K + D+   ES E+
Sbjct: 1170 KYSDDDEEEESEEN 1183



 Score = 28.5 bits (62), Expect = 7.3
 Identities = 31/134 (23%), Positives = 64/134 (47%), Gaps = 13/134 (9%)

Query: 119 EEFETDSDQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATD 178
           E+ E + ++ ++    + SP++      SR   K  +   +K  K+  + + + ++E+T 
Sbjct: 760 EKTEKEEEKTNVGRTLRRSPRI------SRPTAKVAEIRDQKADKKRGEGEDEVEEESTA 813

Query: 179 ITADSSSEF---SEETGASGTRKGKQPHK-RKKKSRKKSLKKPALFLEAESNTSHSDDSA 234
           +      E    SE+   S   K K   K R   SR +   K +   E+E + S   + +
Sbjct: 814 LQKTDKKEILKKSEKDTNSKVSKVKPKGKVRWTGSRTRGRWKYSSNDESEGSGS---EKS 870

Query: 235 SSSSEESEERDTKK 248
           S++SEE EE+++++
Sbjct: 871 SAASEEEEEKESEE 884


>gi|148746195 trichohyalin [Homo sapiens]
          Length = 1943

 Score = 51.2 bits (121), Expect = 1e-06
 Identities = 62/289 (21%), Positives = 124/289 (42%), Gaps = 30/289 (10%)

Query: 23   KIQEESDMWKIRELEKQMEDAYRGTKRKMLPSSSSRMRSDGFDEESQR----YYWRPKNE 78
            ++Q+E +     E EK+ ++  R  + +       + R   + +E QR    + W P+ E
Sbjct: 1175 ELQQEEEQLLREEQEKRRQERERQYREE--EELQRQKRKQRYRDEDQRSDLKWQWEPEKE 1232

Query: 79   ISGTLEDDFLKAKSWNKKFYDYE-ANMPDRWGHSGYKELYPEEFETDSDQQDITNGKKTS 137
             +      + K +  N++F   E + + DR      + L  E+ E D +Q+     ++  
Sbjct: 1233 NAVRDNKVYCKGRE-NEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDR 1291

Query: 138  --PQVKSSTHESRKHKK--SKKSHKKKQKKRSHKKQKKSKKEATDITADSSSEFSEETGA 193
              P+ +    E +K  K   +KS ++KQ  R  +++K+ ++E       +  +F EE   
Sbjct: 1292 HFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQE-------TDRKFREEEQL 1344

Query: 194  SGTRKGKQPHKRKKKSRK------KSLKKPALFLEAESNTSHSDDSASSSSEESEER--D 245
               R+ +QP +R+++ RK      +  ++   FLE E      +       EE + R  +
Sbjct: 1345 LQERE-EQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQE 1403

Query: 246  TKKTKRKKREKKAHTSVANNEIQERTNK--RTNWKVATDERSAESSEDD 292
             ++  R+ R++K          QER  K      +V   ER  +  E++
Sbjct: 1404 REQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEE 1452



 Score = 38.5 bits (88), Expect = 0.007
 Identities = 44/256 (17%), Positives = 104/256 (40%), Gaps = 26/256 (10%)

Query: 23  KIQEESDMWKIRELEKQMEDAYRGTKRKMLPSSSSRMRSDGFDEESQRYYWRPKNEISGT 82
           +++ E  + + ++L ++ E+     K +         R     E+ +R  W  + E +  
Sbjct: 412 QLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKR-----EQEERRDWLKREEETER 466

Query: 83  LEDDFLKAKSWNKKFYDYEANMPDRWGHSGYKELYPEEFETDSDQQDITNGKKTSPQVKS 142
            E +  + K   K+  D E    +RW       L  EE E    Q+      +   Q++ 
Sbjct: 467 HEQE--RRKQQLKR--DQEEERRERW-------LKLEEEERREQQE------RREQQLRR 509

Query: 143 STHESRKH--KKSKKSHKKKQKKRSHKKQKKSKKEATD--ITADSSSEFSEETGASGTRK 198
              E R+   K+ ++  + +Q+ RS ++ ++ ++E  +  +  +      +E      ++
Sbjct: 510 EQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKR 569

Query: 199 GKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEERDTKKTKRKKREKKA 258
            ++  + +   R++  ++  L  E E               E EER  ++ KR++ E++ 
Sbjct: 570 EQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEER 629

Query: 259 HTSVANNEIQERTNKR 274
              +  +E QE   ++
Sbjct: 630 RQQLLKSEEQEERRQQ 645



 Score = 37.7 bits (86), Expect = 0.012
 Identities = 37/244 (15%), Positives = 96/244 (39%), Gaps = 23/244 (9%)

Query: 19   DAHNKIQEESDMWKIRELEKQMEDAYRGTKRKMLPSSSSRMRSDGFDEESQRYYWRPKNE 78
            +   ++  +    K  + E+Q+    RG +R+       R       E  ++   R + +
Sbjct: 1519 EEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERD 1578

Query: 79   ISGTLEDDFLKAKSWNKKFYDYEANMPDRWGHSGYKELYPEEFETDS------DQQDITN 132
                LE+  ++ +   +KF + E  +  + G    ++    +F  D       ++Q +  
Sbjct: 1579 RKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHR 1638

Query: 133  GKKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITADSSSEFSEETG 192
             ++    ++      R+ ++ +  H + +K R  ++  +  +E      +   +F EE  
Sbjct: 1639 QERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREE-- 1696

Query: 193  ASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEERDTKKTKRK 252
                   +Q  +R+++ RK        FL+ E      +       EE   ++T++ + +
Sbjct: 1697 -------EQQLRRQERERK--------FLQEEQQLRRQELERKFREEEQLRQETEQEQLR 1741

Query: 253  KREK 256
            ++E+
Sbjct: 1742 RQER 1745



 Score = 37.0 bits (84), Expect = 0.021
 Identities = 47/288 (16%), Positives = 110/288 (38%), Gaps = 52/288 (18%)

Query: 26  EESDMWKIRELEKQMEDAYRGTKRKMLPSSSSRMRSDGFDEESQRYYWRPKNEISGTLED 85
           EE    ++ + E+Q E   +  +R+       R++ +   EE +R   R K E      +
Sbjct: 626 EEERRQQLLKSEEQEERRQQQLRREQQERREQRLKRE---EEEERLEQRLKREHEEERRE 682

Query: 86  DFLKAKSWNKKFYDYEANMPDRWGHSGYKELYPEEFETDSDQQDITNGKKTSPQVKSSTH 145
             L  +   +     ++ +P        K  +  E E D+ Q  + +  +     +    
Sbjct: 683 QELAEEEQEQARERIKSRIP--------KWQWQLESEADARQSKVYSRPRKQEGQRRRQE 734

Query: 146 ESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITADSSSEFSEETGASGT--------- 196
           +  K ++ +   + ++++R+H++Q++ +++  D T    +E   E G             
Sbjct: 735 QEEKRRRRESELQWQEEERAHRQQQE-EEQRRDFTWQWQAEEKSERGRQRLSARPPLREQ 793

Query: 197 --------------------RKGKQPHKRKKKSRKKSL-----------KKPALFLEAES 225
                                + K+  +R+++ R+K L           ++ A  L+ E 
Sbjct: 794 RERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEE 853

Query: 226 NTSHSDDSASSSSEESEERDTKKTKRKKREKKAHTSVANNEIQERTNK 273
           +    D     S E+  ++  +    ++R+++ HT  A   +QE+  K
Sbjct: 854 DGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRK 901



 Score = 36.2 bits (82), Expect = 0.035
 Identities = 47/297 (15%), Positives = 114/297 (38%), Gaps = 23/297 (7%)

Query: 16   RHT-DAHNKIQEE--SDMWKIRELEKQMEDAYRGTKRKMLPSSSSRMRSDGFDEESQRYY 72
            RHT  A   +QE+   +   ++E E++++   R  +R+       R       EE Q   
Sbjct: 886  RHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLR 945

Query: 73   WRPKNEISGTLEDDFLKAKSWNKKFYDYEANMPDRWGHSGYKELYPEEFETDSDQQDITN 132
               +       E  + K K   +K        P++      ++ Y EE E   +++ +  
Sbjct: 946  EEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLR 1005

Query: 133  GKKTSPQVKSSTHESRKHKKSKKSH----KKKQKKRSHKKQKKSKKEATDITADSSSEFS 188
             ++   + +    + RK  + ++      +++++KR  +++++  +E  ++  +      
Sbjct: 1006 EEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLG 1065

Query: 189  EETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEES------- 241
            EE     TR+ ++  ++ +K  +   ++  L  E        +       EE        
Sbjct: 1066 EERE---TRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQ 1122

Query: 242  ------EERDTKKTKRKKREKKAHTSVANNEIQERTNKRTNWKVATDERSAESSEDD 292
                  E+R  ++ +R+ RE++         ++E   KR   ++    R  E  + +
Sbjct: 1123 LLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQE 1179



 Score = 35.4 bits (80), Expect = 0.060
 Identities = 34/244 (13%), Positives = 91/244 (37%), Gaps = 15/244 (6%)

Query: 58  RMRSDGFDEESQRYYWRPKNEISGTLEDDFLKAKSWNKKFYDYEANMPDRWGHSGYKELY 117
           R R D   +E +   WR +  +    E+   + +   ++    E     +      +EL 
Sbjct: 231 RERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLER---QELR 287

Query: 118 PEEFETDSDQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEAT 177
            E  E +  QQ +   ++   + +    E ++ ++ ++  +++Q++R  ++ ++ ++E  
Sbjct: 288 RERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERR 347

Query: 178 DITADSSSEFS-----------EETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESN 226
           +       E             EE      R+ +Q  + ++  R++ L++    L  E  
Sbjct: 348 EQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQ-LRREQQ 406

Query: 227 TSHSDDSASSSSEESEERDTKKTKRKKREKKAHTSVANNEIQERTNKRTNWKVATDERSA 286
                          E++  ++ + ++ E+K         ++    +R +W    +E   
Sbjct: 407 LRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETER 466

Query: 287 ESSE 290
              E
Sbjct: 467 HEQE 470



 Score = 35.0 bits (79), Expect = 0.078
 Identities = 39/234 (16%), Positives = 96/234 (41%), Gaps = 23/234 (9%)

Query: 25  QEESDMWKIRELEKQMEDAYRGTKRK---------MLPSSSSRMRSDGFDEESQRYYWRP 75
           +E  +    RE EK++E   R  + K         +L     R +     E+ +R   R 
Sbjct: 543 EERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRL 602

Query: 76  KNEISGTLEDDFLKAKSWNKKFYDYEANMPDRWGHSGYKELYPEEFETDSDQQDITNGK- 134
           K E    LE +  + +   ++  + E            ++L   E + +  QQ +   + 
Sbjct: 603 KREEVERLEQEERREQRLKREEPEEERR----------QQLLKSEEQEERRQQQLRREQQ 652

Query: 135 -KTSPQVKSSTHESRKHKKSKKSHKKKQKKR--SHKKQKKSKKEATDITADSSSEFSEET 191
            +   ++K    E R  ++ K+ H+++++++  + ++Q+++++           +   E 
Sbjct: 653 ERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEA 712

Query: 192 GASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEERD 245
            A  ++   +P K++ + R++  ++     E+E      + +     EE + RD
Sbjct: 713 DARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRD 766



 Score = 34.3 bits (77), Expect = 0.13
 Identities = 42/276 (15%), Positives = 104/276 (37%), Gaps = 39/276 (14%)

Query: 16   RHTDAHNKIQEESDMWKIRELEKQMEDAYRGTKRKMLPSSSSRMRSDGFDEESQRYYWRP 75
            R  +   +  EE +  + RE  +Q+++   G +       S   R D      Q++ W+ 
Sbjct: 825  REREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRD------QKWRWQL 878

Query: 76   KNEISGTLEDDFLKAKSWNKKFYDYEANMPDRWGHSGYKELYPEEFETDSDQQDITNGKK 135
            + E        + K     +   + +    +       +EL  EE E    Q+     ++
Sbjct: 879  EEERKRRRHTLYAKPALQEQLRKEQQLLQEEE------EELQREEREKRRRQEQ---ERQ 929

Query: 136  TSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITADSSSEFSEETGASG 195
               + +    E +  ++ ++  ++++++R ++K KK +++   +                
Sbjct: 930  YREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLL--------------- 974

Query: 196  TRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEERDTKKTKRKKRE 255
               G++P KR+++ R+K       + E E      +       E+   ++ ++  RKK E
Sbjct: 975  ---GEEPEKRRRQEREKK------YREEEELQQEEEQLLREEREKRRRQEWERQYRKKDE 1025

Query: 256  KKAHTSVANNEIQERTNKRTNWKVATDERSAESSED 291
             +        E +E+   +   +   +E   +  E+
Sbjct: 1026 LQQEEEQLLREEREKRRLQERERQYREEEELQQEEE 1061



 Score = 32.3 bits (72), Expect = 0.51
 Identities = 31/233 (13%), Positives = 89/233 (38%), Gaps = 17/233 (7%)

Query: 25  QEESDMWKIRELEKQMEDAYRGTKRKMLPSSSSRMRSDGFDEESQRYYWRPKNEISGTLE 84
           +EE   W+ RE   + E+       K+      R R    +EE  R            LE
Sbjct: 240 EEEEKEWRKRETVLRKEE------EKLQEEEPQRQRELQEEEEQLR-----------KLE 282

Query: 85  DDFLKAKSWNKKFYDYEANMPDRWGHSGYKELYPEEFETDSDQQDITNGKKTSPQVKSST 144
              L+ +   ++          +      +E   ++ E    Q+     ++   Q     
Sbjct: 283 RQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRRE 342

Query: 145 HESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITADSSSEFSEETGASGTRKGKQPHK 204
            E R+ ++ ++  +++++++  +++++ ++    +  +      ++       + +Q  +
Sbjct: 343 QEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLR 402

Query: 205 RKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEERDTKKTKRKKREKK 257
           R+++ R++   +    L  E       +      +  +ER  ++ KR++ E++
Sbjct: 403 REQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERR 455



 Score = 29.3 bits (64), Expect = 4.3
 Identities = 34/250 (13%), Positives = 96/250 (38%), Gaps = 32/250 (12%)

Query: 25  QEESDMWKIRELEKQMEDAYRGTKRKMLPSSSSRMRSDGFDEESQRYYWRPKNEISGTLE 84
           ++E D  +    ++Q+E+   G +R+       R  ++G +E+S++     + +     E
Sbjct: 114 RQEEDQRRFEPRDRQLEEE-PGQRRRQKRQEQERELAEG-EEQSEKQERLEQRDRQRRDE 171

Query: 85  DDFLKAKSWNKKFYDYEANMPDRWGHSGYKELYPEEFETDSDQQDITNGKKTSPQVKSST 144
           + + + + W ++                      EE   + +Q     G +T        
Sbjct: 172 ELWRQRQEWQER----------------------EERRAEEEQLQSCKGHETE------- 202

Query: 145 HESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITADSSSEFSEETGASGTRKGKQPHK 204
            E    ++ ++    + +++  +++++ ++E  D       E       +  RK ++  +
Sbjct: 203 -EFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQ 261

Query: 205 RKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEERDTKKTKRKKREKKAHTSVAN 264
            ++  R++ L++    L          +      ++   R  ++ +RK+ E++       
Sbjct: 262 EEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEER 321

Query: 265 NEIQERTNKR 274
            E QER  ++
Sbjct: 322 REQQERREQQ 331


>gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain
           containing B [Homo sapiens]
          Length = 546

 Score = 51.2 bits (121), Expect = 1e-06
 Identities = 52/242 (21%), Positives = 98/242 (40%), Gaps = 25/242 (10%)

Query: 34  RELEKQMEDAYRGTKRKMLPSSSSRMRSDGFDEESQRYYWRPKNEISGTLEDDFLKAKSW 93
           RELE++ E      + K       R RS     E +R   R ++       D     +  
Sbjct: 293 RELEREKERQRLEREAKEREKERRRSRSIDRGLERRRSRSRERHRSRSRSRD-----RKG 347

Query: 94  NKKFYDYEANMPDRWGHSGYKELYPEEFETDSDQQDITNGKKTSPQVKSSTHESRKHKKS 153
           +++  D E    +  G    ++ Y +E   + +++   + +++  Q      E +KHK+ 
Sbjct: 348 DRRDRDREREKENERGRRRDRD-YDKERGNEREKERERSRERSKEQRSRGEVEEKKHKED 406

Query: 154 KKSHKKKQKKRSHKKQKKSKKEATDITADSSSEFSEETGA-SGTRKGKQPHKRKKKSRKK 212
           K   + +  KR  KK+KK  +  +      S   S   G  S +R  ++  K K +S++K
Sbjct: 407 KDDRRHRDDKRDSKKEKKHSRSRSRERKHRSRSRSRNAGKRSRSRSKEKSSKHKNESKEK 466

Query: 213 SLKKPALFLEAESNTSHSDDSASSSSEESEERDTKKTKRKKREKKAHTSVANNEIQERTN 272
           S K+      + S +    DS   S +       +K++++ R K            ER++
Sbjct: 467 SNKR------SRSGSQGRTDSVEKSKKREHSPSKEKSRKRSRSK------------ERSH 508

Query: 273 KR 274
           KR
Sbjct: 509 KR 510



 Score = 50.8 bits (120), Expect = 1e-06
 Identities = 51/245 (20%), Positives = 105/245 (42%), Gaps = 23/245 (9%)

Query: 25  QEESDMWKIRELEKQMEDAYRGTKRKMLPSSSSRMRS-DGFDEESQRYYWRPKNEISGTL 83
           + E +  + R +++ +E     ++ +    S SR R  D  D + +R     +NE     
Sbjct: 310 EREKERRRSRSIDRGLERRRSRSRERHRSRSRSRDRKGDRRDRDRER---EKENERGRRR 366

Query: 84  EDDFLKAKSWNKKFYDYEANMPDRWGHSGYKELYPEEFETDSDQQDITNGKKTSPQVKS- 142
           + D+ K +  N++  + E +           E+  ++ + D D +   + K+ S + K  
Sbjct: 367 DRDYDKERG-NEREKERERSRERSKEQRSRGEVEEKKHKEDKDDRRHRDDKRDSKKEKKH 425

Query: 143 --STHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITADSSSEFSEETGASGTR--- 197
             S    RKH+   +S    ++ RS  K+K SK +      + S E S +   SG++   
Sbjct: 426 SRSRSRERKHRSRSRSRNAGKRSRSRSKEKSSKHK------NESKEKSNKRSRSGSQGRT 479

Query: 198 ------KGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEERDTKKTKR 251
                 K ++    K+KSRK+S  K        S++    D       +S E+++++ + 
Sbjct: 480 DSVEKSKKREHSPSKEKSRKRSRSKERSHKRDHSDSKDQSDKHDRRRSQSIEQESQEKQH 539

Query: 252 KKREK 256
           K +++
Sbjct: 540 KNKDE 544



 Score = 50.1 bits (118), Expect = 2e-06
 Identities = 34/152 (22%), Positives = 71/152 (46%), Gaps = 7/152 (4%)

Query: 141 KSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDIT-ADSSSEFSEETGASGTRKG 199
           K   +E  K ++  +   K+Q+ R   ++KK K++  D    D   +  +E   S +R  
Sbjct: 372 KERGNEREKERERSRERSKEQRSRGEVEEKKHKEDKDDRRHRDDKRDSKKEKKHSRSRSR 431

Query: 200 KQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEERDTKKTKRKKREKKAH 259
           ++ H  + +SR ++  K +     E ++ H ++S   S++ S      +T   ++ KK  
Sbjct: 432 ERKH--RSRSRSRNAGKRSRSRSKEKSSKHKNESKEKSNKRSRSGSQGRTDSVEKSKKRE 489

Query: 260 TSVANNEIQERTNKRTNWKVATDERSAESSED 291
            S +    +E++ KR+  K  + +R    S+D
Sbjct: 490 HSPS----KEKSRKRSRSKERSHKRDHSDSKD 517



 Score = 43.9 bits (102), Expect = 2e-04
 Identities = 37/173 (21%), Positives = 73/173 (42%), Gaps = 6/173 (3%)

Query: 118 PEEFETDSDQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEAT 177
           P   + + DQQ  T  +K     K    E  +H + ++S   ++     +  ++S+  + 
Sbjct: 222 PVPVQKNIDQQIKTRPRKIKKDGKEGAEEIDRHVERRRSRSPRRSLSPRRSPRRSRSRSH 281

Query: 178 DITADSSSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKP-ALFLEAESNTSHSDDSASS 236
                 SS F  E       K +Q  +R+ K R+K  ++  ++    E   S S +   S
Sbjct: 282 HREGHGSSSFDREL---EREKERQRLEREAKEREKERRRSRSIDRGLERRRSRSRERHRS 338

Query: 237 SSEESEERDTKKTKRKKREKKAHTSVANNE--IQERTNKRTNWKVATDERSAE 287
            S   + +  ++ + ++REK+       +    +ER N+R   +  + ERS E
Sbjct: 339 RSRSRDRKGDRRDRDREREKENERGRRRDRDYDKERGNEREKERERSRERSKE 391



 Score = 32.0 bits (71), Expect = 0.66
 Identities = 41/199 (20%), Positives = 81/199 (40%), Gaps = 30/199 (15%)

Query: 34  RELEKQMEDAYRGTKRKMLPSSSSRMRSDGFDEESQRYYWRPKNEIS-GTLEDDFLKAKS 92
           RE EK+ E   RG +R        + R +  ++E +R   R K + S G +E+   K   
Sbjct: 354 REREKENE---RGRRRDR---DYDKERGNEREKERERSRERSKEQRSRGEVEEKKHKEDK 407

Query: 93  WNKKFYDYEANMPDRWGHSGYKELYPEEFETDSDQQDITNGKKTSPQVKSSTHESRKHKK 152
            +++  D + +      HS  +     +  + S  ++     ++  + KSS H++   +K
Sbjct: 408 DDRRHRDDKRDSKKEKKHSRSRSR-ERKHRSRSRSRNAGKRSRSRSKEKSSKHKNESKEK 466

Query: 153 S-------------------KKSH---KKKQKKRSHKKQKKSKKEATDITADSSSEFSEE 190
           S                   K+ H   K+K +KRS  K++  K++ +D    S       
Sbjct: 467 SNKRSRSGSQGRTDSVEKSKKREHSPSKEKSRKRSRSKERSHKRDHSDSKDQSDKHDRRR 526

Query: 191 TGASGTRKGKQPHKRKKKS 209
           + +      ++ HK K ++
Sbjct: 527 SQSIEQESQEKQHKNKDET 545



 Score = 31.2 bits (69), Expect = 1.1
 Identities = 23/92 (25%), Positives = 42/92 (45%), Gaps = 4/92 (4%)

Query: 204 KRKKKSRKKSLKKPALFLEAESNTSHSDDSASSS----SEESEERDTKKTKRKKREKKAH 259
           +R+ +S ++SL        + S + H +   SSS     E  +ER   + + K+REK+  
Sbjct: 257 RRRSRSPRRSLSPRRSPRRSRSRSHHREGHGSSSFDRELEREKERQRLEREAKEREKERR 316

Query: 260 TSVANNEIQERTNKRTNWKVATDERSAESSED 291
            S + +   ER   R+  +  +  RS +   D
Sbjct: 317 RSRSIDRGLERRRSRSRERHRSRSRSRDRKGD 348


>gi|50409738 SRp25 nuclear protein isoform 3 [Homo sapiens]
          Length = 352

 Score = 51.2 bits (121), Expect = 1e-06
 Identities = 32/125 (25%), Positives = 59/125 (47%), Gaps = 6/125 (4%)

Query: 150 HKKSKKSHKKKQKKRSHKKQKKSKKEATDITADSSSEFSEETGASGTRKGKQPHKRKKKS 209
           H  S+K  + + + R    +K+ KK   D + + S+  S+   AS     ++  K+K + 
Sbjct: 126 HVGSRKRSRSRSRSRGRGSEKRKKKSRKDTSRNCSASTSQGRKASTAPGAEERSKQKARR 185

Query: 210 RKKSLKKPALFLEAESNTSHSDDSASSSS------EESEERDTKKTKRKKREKKAHTSVA 263
           R +S    +    + S++S S  S+SSS       +  ++R  KK KRKK +KK      
Sbjct: 186 RTRSSSSSSSSSSSSSSSSSSSSSSSSSDGRKKRGKYKDKRRKKKKKRKKLKKKGKEKAE 245

Query: 264 NNEIQ 268
             +++
Sbjct: 246 AQQVE 250



 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 32/115 (27%), Positives = 55/115 (47%), Gaps = 11/115 (9%)

Query: 143 STHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITADSSSEFSEETGASGTRKGKQP 202
           S   SR   +S+    +K+KK+S K   +      + +A +S      T      + KQ 
Sbjct: 129 SRKRSRSRSRSRGRGSEKRKKKSRKDTSR------NCSASTSQGRKASTAPGAEERSKQK 182

Query: 203 HKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEERDTKKTKRKKREKK 257
            +R+ +S   S         + S++S S  S+SSSS+  ++R   K KR+K++KK
Sbjct: 183 ARRRTRSSSSSSSS-----SSSSSSSSSSSSSSSSSDGRKKRGKYKDKRRKKKKK 232



 Score = 44.7 bits (104), Expect = 1e-04
 Identities = 37/137 (27%), Positives = 63/137 (45%), Gaps = 7/137 (5%)

Query: 125 SDQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKK-KQKKRSHKKQKKSKKEATDITADS 183
           S+++   + K TS    +ST + RK   +  + ++ KQK R   +   S   ++  ++ S
Sbjct: 144 SEKRKKKSRKDTSRNCSASTSQGRKASTAPGAEERSKQKARRRTRSSSSSSSSSSSSSSS 203

Query: 184 SSEFSEETGASGTRK-GKQPHKRKKK-----SRKKSLKKPALFLEAESNTSHSDDSASSS 237
           SS  S  + + G +K GK   KR+KK       KK  K+ A   + E+    S D    S
Sbjct: 204 SSSSSSSSSSDGRKKRGKYKDKRRKKKKKRKKLKKKGKEKAEAQQVEALPGPSLDQWHRS 263

Query: 238 SEESEERDTKKTKRKKR 254
           + E E+      ++K R
Sbjct: 264 AGEEEDGPVLTDEQKSR 280



 Score = 38.1 bits (87), Expect = 0.009
 Identities = 31/152 (20%), Positives = 61/152 (40%), Gaps = 9/152 (5%)

Query: 123 TDSDQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITAD 182
           + S     ++   +S    SS    ++ K   K  KKK+K++  KK+ K K EA  + A 
Sbjct: 193 SSSSSSSSSSSSSSSSSSSSSDGRKKRGKYKDKRRKKKKKRKKLKKKGKEKAEAQQVEAL 252

Query: 183 SSSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESE 242
                 +   ++G  +       ++KSR +++K           T    D+  S   +  
Sbjct: 253 PGPSLDQWHRSAGEEEDGPVLTDEQKSRIQAMK---------PMTKEEWDARQSIIRKVV 303

Query: 243 ERDTKKTKRKKREKKAHTSVANNEIQERTNKR 274
           + +T +T+  K + +    +   E     NK+
Sbjct: 304 DPETGRTRLIKGDGEVLEEIVTKERHREINKQ 335


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.302    0.118    0.322 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 10,964,861
Number of Sequences: 37866
Number of extensions: 508867
Number of successful extensions: 12424
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 482
Number of HSP's successfully gapped in prelim test: 708
Number of HSP's that attempted gapping in prelim test: 4308
Number of HSP's gapped (non-prelim): 4598
length of query: 292
length of database: 18,247,518
effective HSP length: 101
effective length of query: 191
effective length of database: 14,423,052
effective search space: 2754802932
effective search space used: 2754802932
T: 11
A: 40
X1: 17 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (21.8 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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