BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|131888281 hypothetical protein LOC55216 isoform b [Homo sapiens] (292 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|131888281 hypothetical protein LOC55216 isoform b [Homo sapiens] 589 e-169 gi|131889432 hypothetical protein LOC55216 isoform a [Homo sapiens] 585 e-167 gi|131889391 hypothetical protein LOC55216 isoform a [Homo sapiens] 585 e-167 gi|168229156 NFKB activating protein [Homo sapiens] 74 2e-13 gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1... 67 2e-11 gi|56090620 NFKB activating protein-like [Homo sapiens] 66 3e-11 gi|27734775 hypothetical protein LOC286499 [Homo sapiens] 63 3e-10 gi|91206454 hypothetical protein LOC257415 isoform 2 [Homo sapiens] 59 5e-09 gi|91206456 hypothetical protein LOC257415 isoform 1 [Homo sapiens] 59 5e-09 gi|4557509 cylicin 2 [Homo sapiens] 58 9e-09 gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 56 3e-08 gi|239749449 PREDICTED: hypothetical protein [Homo sapiens] 55 1e-07 gi|42560244 peptidylprolyl isomerase G [Homo sapiens] 55 1e-07 gi|40068059 CBF1 interacting corepressor [Homo sapiens] 54 1e-07 gi|239508778 PREDICTED: hypothetical protein, partial [Homo sapi... 54 1e-07 gi|151301228 formin binding protein 3 [Homo sapiens] 54 1e-07 gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo s... 54 1e-07 gi|50409756 SRp25 nuclear protein isoform 1 [Homo sapiens] 53 3e-07 gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ... 53 3e-07 gi|104526627 triadin [Homo sapiens] 53 3e-07 gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [... 53 3e-07 gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 52 5e-07 gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens] 52 6e-07 gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens] 52 6e-07 gi|21040326 SON DNA-binding protein isoform F [Homo sapiens] 52 8e-07 gi|21040314 SON DNA-binding protein isoform B [Homo sapiens] 52 8e-07 gi|38788333 remodeling and spacing factor 1 [Homo sapiens] 51 1e-06 gi|148746195 trichohyalin [Homo sapiens] 51 1e-06 gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain ... 51 1e-06 gi|50409738 SRp25 nuclear protein isoform 3 [Homo sapiens] 51 1e-06 >gi|131888281 hypothetical protein LOC55216 isoform b [Homo sapiens] Length = 292 Score = 589 bits (1519), Expect = e-169 Identities = 292/292 (100%), Positives = 292/292 (100%) Query: 1 MSRIPLGKVLLRNVIRHTDAHNKIQEESDMWKIRELEKQMEDAYRGTKRKMLPSSSSRMR 60 MSRIPLGKVLLRNVIRHTDAHNKIQEESDMWKIRELEKQMEDAYRGTKRKMLPSSSSRMR Sbjct: 1 MSRIPLGKVLLRNVIRHTDAHNKIQEESDMWKIRELEKQMEDAYRGTKRKMLPSSSSRMR 60 Query: 61 SDGFDEESQRYYWRPKNEISGTLEDDFLKAKSWNKKFYDYEANMPDRWGHSGYKELYPEE 120 SDGFDEESQRYYWRPKNEISGTLEDDFLKAKSWNKKFYDYEANMPDRWGHSGYKELYPEE Sbjct: 61 SDGFDEESQRYYWRPKNEISGTLEDDFLKAKSWNKKFYDYEANMPDRWGHSGYKELYPEE 120 Query: 121 FETDSDQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDIT 180 FETDSDQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDIT Sbjct: 121 FETDSDQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDIT 180 Query: 181 ADSSSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEE 240 ADSSSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEE Sbjct: 181 ADSSSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEE 240 Query: 241 SEERDTKKTKRKKREKKAHTSVANNEIQERTNKRTNWKVATDERSAESSEDD 292 SEERDTKKTKRKKREKKAHTSVANNEIQERTNKRTNWKVATDERSAESSEDD Sbjct: 241 SEERDTKKTKRKKREKKAHTSVANNEIQERTNKRTNWKVATDERSAESSEDD 292 >gi|131889432 hypothetical protein LOC55216 isoform a [Homo sapiens] Length = 293 Score = 585 bits (1507), Expect = e-167 Identities = 292/293 (99%), Positives = 292/293 (99%), Gaps = 1/293 (0%) Query: 1 MSRIPLGKVLLRNVIRHTDAHNKIQEESDMWKIRELEKQMEDAYRGTKRKMLPSSSSRMR 60 MSRIPLGKVLLRNVIRHTDAHNKIQEESDMWKIRELEKQMEDAYRGTKRKMLPSSSSRMR Sbjct: 1 MSRIPLGKVLLRNVIRHTDAHNKIQEESDMWKIRELEKQMEDAYRGTKRKMLPSSSSRMR 60 Query: 61 SDGFDEESQRYYWRPKNEISGTLEDDFLKAKSWNKKFYDYEANMPDRWGHSGYKELYPEE 120 SDGFDEESQRYYWRPKNEISGTLEDDFLKAKSWNKKFYDYEANMPDRWGHSGYKELYPEE Sbjct: 61 SDGFDEESQRYYWRPKNEISGTLEDDFLKAKSWNKKFYDYEANMPDRWGHSGYKELYPEE 120 Query: 121 FETDS-DQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDI 179 FETDS DQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDI Sbjct: 121 FETDSSDQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDI 180 Query: 180 TADSSSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSE 239 TADSSSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSE Sbjct: 181 TADSSSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSE 240 Query: 240 ESEERDTKKTKRKKREKKAHTSVANNEIQERTNKRTNWKVATDERSAESSEDD 292 ESEERDTKKTKRKKREKKAHTSVANNEIQERTNKRTNWKVATDERSAESSEDD Sbjct: 241 ESEERDTKKTKRKKREKKAHTSVANNEIQERTNKRTNWKVATDERSAESSEDD 293 >gi|131889391 hypothetical protein LOC55216 isoform a [Homo sapiens] Length = 293 Score = 585 bits (1507), Expect = e-167 Identities = 292/293 (99%), Positives = 292/293 (99%), Gaps = 1/293 (0%) Query: 1 MSRIPLGKVLLRNVIRHTDAHNKIQEESDMWKIRELEKQMEDAYRGTKRKMLPSSSSRMR 60 MSRIPLGKVLLRNVIRHTDAHNKIQEESDMWKIRELEKQMEDAYRGTKRKMLPSSSSRMR Sbjct: 1 MSRIPLGKVLLRNVIRHTDAHNKIQEESDMWKIRELEKQMEDAYRGTKRKMLPSSSSRMR 60 Query: 61 SDGFDEESQRYYWRPKNEISGTLEDDFLKAKSWNKKFYDYEANMPDRWGHSGYKELYPEE 120 SDGFDEESQRYYWRPKNEISGTLEDDFLKAKSWNKKFYDYEANMPDRWGHSGYKELYPEE Sbjct: 61 SDGFDEESQRYYWRPKNEISGTLEDDFLKAKSWNKKFYDYEANMPDRWGHSGYKELYPEE 120 Query: 121 FETDS-DQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDI 179 FETDS DQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDI Sbjct: 121 FETDSSDQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDI 180 Query: 180 TADSSSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSE 239 TADSSSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSE Sbjct: 181 TADSSSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSE 240 Query: 240 ESEERDTKKTKRKKREKKAHTSVANNEIQERTNKRTNWKVATDERSAESSEDD 292 ESEERDTKKTKRKKREKKAHTSVANNEIQERTNKRTNWKVATDERSAESSEDD Sbjct: 241 ESEERDTKKTKRKKREKKAHTSVANNEIQERTNKRTNWKVATDERSAESSEDD 293 >gi|168229156 NFKB activating protein [Homo sapiens] Length = 415 Score = 73.6 bits (179), Expect = 2e-13 Identities = 59/227 (25%), Positives = 98/227 (43%), Gaps = 25/227 (11%) Query: 43 AYRGTKRKMLPSSSSRMRSDGFDEESQRYYW----------RPKNEISGTLEDDFLKAKS 92 +YR R S R F S Y+ +P + ++ L+ K Sbjct: 71 SYRSRSRSRSRERPSAPRGIPFASASSSVYYGSYSRPYGSDKPWPSLLDKEREESLRQKR 130 Query: 93 WNKKFYDYEANMPDRWGHSGYKELYPEEFETDSDQ----QDITNGKKTSPQVKSSTHESR 148 +++ E P+ WG L P+ E DSD+ +D K T+ S + + Sbjct: 131 LSERERIGELGAPEVWG------LSPKNPEPDSDEHTPVEDEEPKKSTTSASTSEEEKKK 184 Query: 149 KHKKSKKSHKKKQKKRSHKKQKKSKKEATDITADSSSEFSEETGASGTRKGKQPHKRKKK 208 K +SK+ KK++KK+S K++ K E +D +DS ++ S+E +K K+ K+KK Sbjct: 185 KSSRSKERSKKRRKKKSSKRKHKKYSEDSDSDSDSETDSSDEDNKRRAKKAKKKEKKKKH 244 Query: 209 SRKKSLKKPALFLEAESNTSHSDDSASSSSEESEERDTKKTKRKKRE 255 KK KK ++ + S DS+S S+E + K + K E Sbjct: 245 RSKKYKKK-----RSKKSRKESSDSSSKESQEEFLENPWKDRTKAEE 286 Score = 44.3 bits (103), Expect = 1e-04 Identities = 25/86 (29%), Positives = 43/86 (50%), Gaps = 7/86 (8%) Query: 117 YPEEFETDSDQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEA 176 Y E+ ++DSD + T + + ++K KK +K K + KK K+ KKS+KE+ Sbjct: 209 YSEDSDSDSDSE-------TDSSDEDNKRRAKKAKKKEKKKKHRSKKYKKKRSKKSRKES 261 Query: 177 TDITADSSSEFSEETGASGTRKGKQP 202 +D ++ S E E K ++P Sbjct: 262 SDSSSKESQEEFLENPWKDRTKAEEP 287 Score = 35.0 bits (79), Expect = 0.078 Identities = 32/166 (19%), Positives = 65/166 (39%), Gaps = 17/166 (10%) Query: 144 THESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITADSSS----EFSEETGASGTRKG 199 TH+ + ++ + + RS +++ S + SSS +S G+ Sbjct: 57 THQLGGLSQGSRNQSYRSRSRSRSRERPSAPRGIPFASASSSVYYGSYSRPYGSDKPWPS 116 Query: 200 KQPHKRKKKSRKKSLKK---------PALFLEAESNTSHSDDSASSSSEESEERDTKKTK 250 +R++ R+K L + P ++ + N D + +E ++ T Sbjct: 117 LLDKEREESLRQKRLSERERIGELGAPEVWGLSPKNPEPDSDEHTPVEDEEPKKSTTSAS 176 Query: 251 RKKREKKAHTSVANNEIQER----TNKRTNWKVATDERSAESSEDD 292 + EKK +S + ++R ++KR + K + D S SE D Sbjct: 177 TSEEEKKKKSSRSKERSKKRRKKKSSKRKHKKYSEDSDSDSDSETD 222 >gi|117935038 cylicin, basic protein of sperm head cytoskeleton 1 [Homo sapiens] Length = 651 Score = 67.0 bits (162), Expect = 2e-11 Identities = 51/185 (27%), Positives = 82/185 (44%), Gaps = 14/185 (7%) Query: 117 YPEEFETDSDQQDITNGKKTSPQVKSSTHESRKHKKSKK------SHKKKQKKRSHKKQK 170 YPE TD++ D + + S +K ++ K K +KK S + + K S K +K Sbjct: 366 YPES--TDTESGDAKDARNDSRNLKKASKNDDKKKDAKKITFSTDSESELESKESQKDEK 423 Query: 171 KSKKEATDITADSSSEFSEETGASG-----TRKGKQPHKRKKKSRKKSLKKPALFLEAES 225 K KK++ S E T A ++KGK+ K+ KK KK KK AES Sbjct: 424 KDKKDSKTDNKKSVKNDEESTDADSEPKGDSKKGKKDEKKGKKDSKKDDKKKDAKKNAES 483 Query: 226 NTSHSDDSASSSSEES-EERDTKKTKRKKREKKAHTSVANNEIQERTNKRTNWKVATDER 284 SD + S E++ +KK +K K ++ A + +T +T+ K+ + Sbjct: 484 TEMESDLELKKDKKHSKEKKGSKKDIKKDARKDTESTDAEFDESSKTGFKTSTKIKGSDT 543 Query: 285 SAESS 289 +E S Sbjct: 544 ESEES 548 Score = 52.0 bits (123), Expect = 6e-07 Identities = 45/169 (26%), Positives = 74/169 (43%), Gaps = 19/169 (11%) Query: 132 NGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITADSSSEFSEET 191 N KK+S + + +S+ KK K KK KK KK K E+TD + S + ++T Sbjct: 291 NAKKSSD---AESEDSKDAKKDSKKVKKNVKKDDKKKDVKKDTESTDAESGDSKDERKDT 347 Query: 192 GASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEERDTKKTKR 251 K K KK +KK KK + ES + + S + +++ + D KK Sbjct: 348 K-------KDKKKLKKDDKKKDTKKYPESTDTESGDAKDARNDSRNLKKASKNDDKKKDA 400 Query: 252 KK--------REKKAHTSVANNEIQERTNKRTNWK-VATDERSAESSED 291 KK E ++ S + + ++ +K N K V DE S ++ + Sbjct: 401 KKITFSTDSESELESKESQKDEKKDKKDSKTDNKKSVKNDEESTDADSE 449 Score = 50.8 bits (120), Expect = 1e-06 Identities = 68/259 (26%), Positives = 113/259 (43%), Gaps = 19/259 (7%) Query: 32 KIRELEKQME--DAYRGT---KRKMLPSSSSRMRSDGFDEESQRYYWRPKNEISGTLED- 85 K ++++K E DA G +RK +++ D +++++Y E SG +D Sbjct: 322 KKKDVKKDTESTDAESGDSKDERKDTKKDKKKLKKDDKKKDTKKYPESTDTE-SGDAKDA 380 Query: 86 --DFLKAKSWNKKFYDYEANMPDRWGHSGYKELYPEEFETDS--DQQDI-TNGKKTSPQV 140 D K +K + + EL +E + D D++D T+ KK+ Sbjct: 381 RNDSRNLKKASKNDDKKKDAKKITFSTDSESELESKESQKDEKKDKKDSKTDNKKSVKND 440 Query: 141 KSSTH---ESRKHKKSKKSHKKKQKKRSHK--KQKKSKKEATDITADSSSEFSEETGASG 195 + ST E + K K +KK KK S K K+K +KK A +S E ++ S Sbjct: 441 EESTDADSEPKGDSKKGKKDEKKGKKDSKKDDKKKDAKKNAESTEMESDLELKKDKKHSK 500 Query: 196 TRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEERDTKKTKRKKRE 255 +KG + KK +RK + A F E+ + S ESEE K +KK + Sbjct: 501 EKKGSK-KDIKKDARKDTESTDAEFDESSKTGFKTSTKIKGSDTESEESLYKPGAKKKID 559 Query: 256 KKAHTSVANNEIQERTNKR 274 + TS AN++++ +KR Sbjct: 560 ESDGTS-ANSKMEGLESKR 577 Score = 48.9 bits (115), Expect = 5e-06 Identities = 40/172 (23%), Positives = 75/172 (43%), Gaps = 19/172 (11%) Query: 124 DSDQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITADS 183 D ++D+ KK + + + +S+ +K K KKK KK KK K E+TD Sbjct: 320 DDKKKDV---KKDTESTDAESGDSKDERKDTKKDKKKLKKDDKKKDTKKYPESTD----- 371 Query: 184 SSEFSEETGASGTRKGKQPHKRKKKS--RKKSLKKPALFLEAESNTSHSDDSASSSSEES 241 +E A R + K+ K+ +KK KK ++ES + S E+ Sbjct: 372 ----TESGDAKDARNDSRNLKKASKNDDKKKDAKKITFSTDSESELESKE---SQKDEKK 424 Query: 242 EERDTKKTKRKKREKKAHTSVANNEIQ--ERTNKRTNWKVATDERSAESSED 291 +++D+K +K + ++ A++E + + K+ K D + + +D Sbjct: 425 DKKDSKTDNKKSVKNDEESTDADSEPKGDSKKGKKDEKKGKKDSKKDDKKKD 476 Score = 43.1 bits (100), Expect = 3e-04 Identities = 30/131 (22%), Positives = 60/131 (45%), Gaps = 9/131 (6%) Query: 151 KKSKKSHKKKQKKRSHKKQKKSKKEATDITADSSSEFSEETGASGTRKGKQPHKRKKKSR 210 + + K++ K K + K KK+ K+++D ++ S + +++ K KK + Sbjct: 270 QNNSKNYSLKYTKYTKKDTKKNAKKSSDAESEDSKDAKKDSK-------KVKKNVKKDDK 322 Query: 211 KKSLKKPALFLEAESNTSHSDDSASSSSEESEERDTKKTKRKKREKKAHTSVANNEIQER 270 KK +KK +AES S + + ++ ++D KK KK + T + + ++ Sbjct: 323 KKDVKKDTESTDAESGDSKDERKDTKKDKKKLKKDDKKKDTKKYPES--TDTESGDAKDA 380 Query: 271 TNKRTNWKVAT 281 N N K A+ Sbjct: 381 RNDSRNLKKAS 391 Score = 40.0 bits (92), Expect = 0.002 Identities = 35/120 (29%), Positives = 56/120 (46%), Gaps = 27/120 (22%) Query: 143 STHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITADSSSEFSEETGASGTRKGKQP 202 S + S+ + + KK K++ KK ++D+ SE S++ K+ Sbjct: 269 SQNNSKNYSLKYTKYTKKDTKKNAKK-----------SSDAESEDSKD--------AKKD 309 Query: 203 HKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEERDTKKTKR--KKREKKAHT 260 K+ KK+ KK KK + + ES + S DS + E +DTKK K+ KK +KK T Sbjct: 310 SKKVKKNVKKDDKKKDVKKDTESTDAESGDS------KDERKDTKKDKKKLKKDDKKKDT 363 Score = 38.9 bits (89), Expect = 0.005 Identities = 39/189 (20%), Positives = 76/189 (40%), Gaps = 23/189 (12%) Query: 122 ETDSDQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITA 181 ET+ + Q+ K Q ++ K ++ H K K+ K+ K S ++I + Sbjct: 180 ETNPESQNSKTVSKNCSQKDKKDSKNSKKTNTEFLHTKNNPKKDLKRSKTSNDPISEICS 239 Query: 182 DSS--SEFSEETGASG---------TRKGKQPH---------KRKKKSRKKSLKKPALFL 221 ++S +F G S R Q + K KK KK+ KK + Sbjct: 240 ENSLNVDFLMLVGQSDDESINFDAWLRNYSQNNSKNYSLKYTKYTKKDTKKNAKKSS--- 296 Query: 222 EAESNTSHSDDSASSSSEESEERDTKKTKRKKREKKAHTSVANNEIQERTNKRTNWKVAT 281 +AES S S +++ ++D KK KK + +++ + + K+ K+ Sbjct: 297 DAESEDSKDAKKDSKKVKKNVKKDDKKKDVKKDTESTDAESGDSKDERKDTKKDKKKLKK 356 Query: 282 DERSAESSE 290 D++ ++ + Sbjct: 357 DDKKKDTKK 365 Score = 38.5 bits (88), Expect = 0.007 Identities = 36/161 (22%), Positives = 63/161 (39%), Gaps = 1/161 (0%) Query: 83 LEDDFLKAKSWNKKFYDYEANMPDRWGHSGYKELYPEEFETDSDQQDITNGKKTSPQVKS 142 + F K W + P R ++ L E++ D++ T KK S + Sbjct: 77 IRHSFRKILQWPPIYTAAREQTPFRHLYTSKTHLKKAEYKKSKDEKGGTPLKKDSKKKGG 136 Query: 143 STHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITADSSSEFSEETGASGTRKGKQP 202 S + + K+ + K+Q + K S + + SSSE + E+ S T K Sbjct: 137 SYATNPESKQIVEEKTKRQNEADKTPLKSSHENEQSKKSKSSSETNPESQNSKT-VSKNC 195 Query: 203 HKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEE 243 ++ KK K S K FL ++N + +S++ E Sbjct: 196 SQKDKKDSKNSKKTNTEFLHTKNNPKKDLKRSKTSNDPISE 236 Score = 31.2 bits (69), Expect = 1.1 Identities = 40/193 (20%), Positives = 78/193 (40%), Gaps = 15/193 (7%) Query: 91 KSWNKKFYDYEANMP-DRWGHSGYKELYPEEFETDSDQQDITNGKKTSPQVKSSTHESRK 149 KSWN+K + P R + + L + T D++ + G+K P K H RK Sbjct: 26 KSWNQKHFALTFPKPLQRGTNDKSRPLKSQITVTRHDKRKLEEGQK--PAHKWIRHSFRK 83 Query: 150 HKKSKKSHKKKQKKRSHKKQKKSKKEATDITADSSSEFSEETGASGTRKGKQPHKRKKKS 209 + + +++ + SK T +E+ + G K+ K+K S Sbjct: 84 ILQWPPIYTAAREQTPFRHLYTSK------THLKKAEYKKSKDEKGGTPLKKDSKKKGGS 137 Query: 210 RKKSLKKPALFLEAESNTSHSDDSASSSSEESEE-RDTKKTKRKKREKKAHTSVANNEIQ 268 + + + E + +D + SS E+E+ + +K + E + +V+ N Q Sbjct: 138 YATNPESKQIVEEKTKRQNEADKTPLKSSHENEQSKKSKSSSETNPESQNSKTVSKNCSQ 197 Query: 269 E-----RTNKRTN 276 + + +K+TN Sbjct: 198 KDKKDSKNSKKTN 210 >gi|56090620 NFKB activating protein-like [Homo sapiens] Length = 402 Score = 66.2 bits (160), Expect = 3e-11 Identities = 42/140 (30%), Positives = 72/140 (51%), Gaps = 8/140 (5%) Query: 101 EANMPDRWGHSG-YKELYPEEFETDSDQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKK 159 E P+ WG S + +L +E D++++T+ K +S S S +H+K K S + Sbjct: 130 ELGAPEVWGPSPKFPQLDSDEHTPVEDEEEVTHQKSSS-----SDSNSEEHRKKKTSRSR 184 Query: 160 KQKKRSHKKQKKSKKEATDITADSSSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPAL 219 +KKR +K K+ ++ +D +DS+SE + + +K + K+KKK + K+ KK Sbjct: 185 NKKKRKNKSSKRKHRKYSD--SDSNSESDTNSDSDDDKKRVKAKKKKKKKKHKTKKKKNK 242 Query: 220 FLEAESNTSHSDDSASSSSE 239 + ES+ S DS SE Sbjct: 243 KTKKESSDSSCKDSEEDLSE 262 Score = 50.8 bits (120), Expect = 1e-06 Identities = 45/183 (24%), Positives = 85/183 (46%), Gaps = 16/183 (8%) Query: 109 GHSGYKELYPEEFETDSDQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKK 168 G+ ++ Y EE ++ D + + ++ + + E + S K Q Sbjct: 93 GYRYHRHCYAEERQSAEDYEKEESHRQRRLKERERIGELGAPEVWGPSPKFPQLDSDEHT 152 Query: 169 QKKSKKEATDITADSSSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTS 228 + ++E T + SS SEE T + + KRK KS K+ +K + +++SN Sbjct: 153 PVEDEEEVTHQKSSSSDSNSEEHRKKKTSRSRNKKKRKNKSSKRKHRK---YSDSDSN-- 207 Query: 229 HSDDSASSSSEESEERDTKKTKRKKREKKAHTSVANNEIQERTNKRTNWKVATDERSAES 288 S+ +S S++ ++R K K+KK++KK T +++ NK+T K ++D +S Sbjct: 208 -SESDTNSDSDDDKKR--VKAKKKKKKKKHKT-------KKKKNKKTK-KESSDSSCKDS 256 Query: 289 SED 291 ED Sbjct: 257 EED 259 Score = 33.1 bits (74), Expect = 0.30 Identities = 28/123 (22%), Positives = 56/123 (45%), Gaps = 22/123 (17%) Query: 187 FSEETGASGTRKGKQPHKR---KKKSRKKSLKKPALF--------LEAESNTSHSDDS-- 233 ++EE ++ + ++ H++ K++ R L P ++ L+++ +T D+ Sbjct: 101 YAEERQSAEDYEKEESHRQRRLKERERIGELGAPEVWGPSPKFPQLDSDEHTPVEDEEEV 160 Query: 234 ----ASSSSEESEERDTKKTKRKKREKKAHTSVANNEIQERTNKRTNWKVATDERSAESS 289 +SSS SEE KKT R + +KK N+ +R +++ + + E S Sbjct: 161 THQKSSSSDSNSEEHRKKKTSRSRNKKKR-----KNKSSKRKHRKYSDSDSNSESDTNSD 215 Query: 290 EDD 292 DD Sbjct: 216 SDD 218 Score = 29.6 bits (65), Expect = 3.3 Identities = 29/141 (20%), Positives = 53/141 (37%), Gaps = 3/141 (2%) Query: 67 ESQRYYWRPKNEISGTLEDDFLKAKSWNKKFYDYEANMPDRWGHSGYKELYPE-EFETDS 125 E + K+ S + ++ K K+ + N + H Y + E +T+S Sbjct: 155 EDEEEVTHQKSSSSDSNSEEHRKKKTSRSRNKKKRKNKSSKRKHRKYSDSDSNSESDTNS 214 Query: 126 DQQDITNGKKTSPQVKSSTHESRK--HKKSKKSHKKKQKKRSHKKQKKSKKEATDITADS 183 D D K + K H+++K +KK+KK K S + ++ AD+ Sbjct: 215 DSDDDKKRVKAKKKKKKKKHKTKKKKNKKTKKESSDSSCKDSEEDLSEATWMEQPNVADT 274 Query: 184 SSEFSEETGASGTRKGKQPHK 204 E T + ++P K Sbjct: 275 MDLIGPEAPIIHTSQDEKPLK 295 >gi|27734775 hypothetical protein LOC286499 [Homo sapiens] Length = 248 Score = 63.2 bits (152), Expect = 3e-10 Identities = 55/204 (26%), Positives = 85/204 (41%), Gaps = 17/204 (8%) Query: 69 QRYYWRPK---NEISGTLEDDFLKAKSWNKKFYDYEANMPDRWGH----SGYKELYPEEF 121 Q Y RP+ E+ LE+ K+ +K ++E M + W S K L E Sbjct: 31 QDYLNRPRPTWEEVKKQLENK----KTGSKALAEFEEKMNENWKKELEKSREKLLSGNES 86 Query: 122 ETDSDQQDITNGKKTS-PQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDIT 180 + ++ KK+ SS+ +S + +KKQ KR KK+ +S K + T Sbjct: 87 SSKKRERKKKRKKKSCRSSSSSSSSDSSSSSSDSEDEEKKQGKRRKKKKNRSYKSSQSST 146 Query: 181 ADSSSEFSE-----ETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSAS 235 +S SE E + T K K KK +K L E+ S + + +D + Sbjct: 147 HESESESKESVKKKKKSKDETEKEKDVRSLSKKRKKSYPDDKPLSSESSSESDYEEDVQA 206 Query: 236 SSSEESEERDTKKTKRKKREKKAH 259 EER+ K K KK++KK H Sbjct: 207 KKKRRCEEREQAKEKVKKKKKKQH 230 Score = 56.6 bits (135), Expect = 3e-08 Identities = 41/146 (28%), Positives = 67/146 (45%), Gaps = 16/146 (10%) Query: 146 ESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITADSSSEFSEETGASGTRKGKQPHKR 205 E +K ++KK+ K + K + KKE E S E SG + +R Sbjct: 43 EVKKQLENKKTGSKALAEFEEKMNENWKKEL---------EKSREKLLSGNESSSKKRER 93 Query: 206 KKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEERDTKKTKRKKREKKAHTSVANN 265 KKK +KKS + + S++S SD S+SSS E EE+ K ++KK+ + +S ++ Sbjct: 94 KKKRKKKSCR-------SSSSSSSSDSSSSSSDSEDEEKKQGKRRKKKKNRSYKSSQSST 146 Query: 266 EIQERTNKRTNWKVATDERSAESSED 291 E +K + K + E +D Sbjct: 147 HESESESKESVKKKKKSKDETEKEKD 172 Score = 35.0 bits (79), Expect = 0.078 Identities = 41/160 (25%), Positives = 64/160 (40%), Gaps = 18/160 (11%) Query: 32 KIRELEKQMEDAYRGTKRKMLPSSSSRMRSDGFDEESQRYYWRPKNEI-------SGTLE 84 K RE +K+ + + S SS SD DEE ++ R K + S T E Sbjct: 89 KKRERKKKRKKKSCRSSSSSSSSDSSSSSSDSEDEEKKQGKRRKKKKNRSYKSSQSSTHE 148 Query: 85 DDFLKAKSWNKKFYDYEANMPDRWGHS---GYKELYPE------EFETDSDQQDITNGKK 135 + +S KK + ++ S K+ YP+ E ++SD ++ KK Sbjct: 149 SESESKESVKKKKKSKDETEKEKDVRSLSKKRKKSYPDDKPLSSESSSESDYEEDVQAKK 208 Query: 136 TSPQVKSSTHESRKHKKSKKSHKKKQKKRSHK--KQKKSK 173 + + + KK KK HKK KK+ K KS+ Sbjct: 209 KRRCEEREQAKEKVKKKKKKQHKKHSKKKKKKSGSSHKSR 248 >gi|91206454 hypothetical protein LOC257415 isoform 2 [Homo sapiens] Length = 237 Score = 58.9 bits (141), Expect = 5e-09 Identities = 61/219 (27%), Positives = 94/219 (42%), Gaps = 33/219 (15%) Query: 69 QRYYWRPK---NEISGTLEDDFLKAKSWNKKFYDYEANMPDRWGHSGYKE----LYPEEF 121 Q Y RP+ E+ LE K K +K ++E M + W K L E Sbjct: 21 QDYLNRPRPTWEEVKEQLE----KKKKGSKALAEFEEKMNENWKKELEKHREKLLSGSES 76 Query: 122 ETDSDQQDITNGKKT---------SPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKS 172 + Q+ KK+ S SS+ +S K + +KK+K RSHK + S Sbjct: 77 SSKKRQRKKKEKKKSGRYSSSSSSSSDSSSSSSDSEDEDKKQGKRRKKKKNRSHKSSESS 136 Query: 173 KKEATDITADSSSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDD 232 E + DS + ++ GT K K KK + S KP L E+ S + + ++ Sbjct: 137 MSETESDSKDSLKK--KKKSKDGTEKEKDIKGLSKKRKMYSEDKP-LSSESLSESEYIEE 193 Query: 233 SASSSSEESEERD--TKKTKRKK--------REKKAHTS 261 + + SEER+ T+KTK+KK ++KKA +S Sbjct: 194 VRAKKKKSSEEREKATEKTKKKKKHKKHSKKKKKKAASS 232 Score = 51.2 bits (121), Expect = 1e-06 Identities = 40/144 (27%), Positives = 67/144 (46%), Gaps = 5/144 (3%) Query: 146 ESRKHKKSKKS-HKKKQKKRSHKKQKKSKKEATDITADSSSEFSEETGASGTRKGKQPHK 204 E KH++ S + KKR KK++K K ++ SSS+ S + S KQ + Sbjct: 62 ELEKHREKLLSGSESSSKKRQRKKKEKKKSGRYSSSSSSSSDSSSSSSDSEDEDKKQGKR 121 Query: 205 RKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESE-ERDTKKTKRKKR---EKKAHT 260 RKKK + + E ES++ S S + +E E+D K +K++ E K + Sbjct: 122 RKKKKNRSHKSSESSMSETESDSKDSLKKKKKSKDGTEKEKDIKGLSKKRKMYSEDKPLS 181 Query: 261 SVANNEIQERTNKRTNWKVATDER 284 S + +E + R K +++ER Sbjct: 182 SESLSESEYIEEVRAKKKKSSEER 205 Score = 50.8 bits (120), Expect = 1e-06 Identities = 39/159 (24%), Positives = 73/159 (45%), Gaps = 9/159 (5%) Query: 134 KKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITADSSSEFSEETGA 193 + + P ++ + R + K +K+KK S K +E + E E Sbjct: 14 QSSGPTIQDYLNRPRPTWEEVKEQLEKKKKGS--KALAEFEEKMNENWKKELEKHREKLL 71 Query: 194 SGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEERDTKKTKRKK 253 SG+ + +RKKK +KKS + + S++S SD S+SSS E E++ K +RKK Sbjct: 72 SGSESSSKKRQRKKKEKKKSGRY------SSSSSSSSDSSSSSSDSEDEDKKQGK-RRKK 124 Query: 254 REKKAHTSVANNEIQERTNKRTNWKVATDERSAESSEDD 292 ++ ++H S ++ + ++ + + K + E D Sbjct: 125 KKNRSHKSSESSMSETESDSKDSLKKKKKSKDGTEKEKD 163 Score = 44.3 bits (103), Expect = 1e-04 Identities = 47/191 (24%), Positives = 76/191 (39%), Gaps = 15/191 (7%) Query: 25 QEESDMWKIRELEKQMEDAYRGTKRKMLPSSSSRMRSDGFDEESQRYYWRPKNEISGTLE 84 ++ ++ WK +ELEK E G++ SS R R ++S RY S + Sbjct: 53 EKMNENWK-KELEKHREKLLSGSES----SSKKRQRKKKEKKKSGRY------SSSSSSS 101 Query: 85 DDFLKAKSWNKKFYDYEANMPDRWGHSGYKELYPEEFETDSDQQDITNGKKTSPQVKSST 144 D + S ++ + + + +K ET+SD +D KK S K T Sbjct: 102 SDSSSSSSDSEDEDKKQGKRRKKKKNRSHKSSESSMSETESDSKDSLKKKKKS---KDGT 158 Query: 145 HESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITADSSSEFSEETGASGTRKGKQPHK 204 + + K K K + + + S+ E + + SEE T K K+ K Sbjct: 159 EKEKDIKGLSKKRKMYSEDKPLSSESLSESEYIEEVRAKKKKSSEER-EKATEKTKKKKK 217 Query: 205 RKKKSRKKSLK 215 KK S+KK K Sbjct: 218 HKKHSKKKKKK 228 >gi|91206456 hypothetical protein LOC257415 isoform 1 [Homo sapiens] Length = 247 Score = 58.9 bits (141), Expect = 5e-09 Identities = 61/219 (27%), Positives = 94/219 (42%), Gaps = 33/219 (15%) Query: 69 QRYYWRPK---NEISGTLEDDFLKAKSWNKKFYDYEANMPDRWGHSGYKE----LYPEEF 121 Q Y RP+ E+ LE K K +K ++E M + W K L E Sbjct: 31 QDYLNRPRPTWEEVKEQLE----KKKKGSKALAEFEEKMNENWKKELEKHREKLLSGSES 86 Query: 122 ETDSDQQDITNGKKT---------SPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKS 172 + Q+ KK+ S SS+ +S K + +KK+K RSHK + S Sbjct: 87 SSKKRQRKKKEKKKSGRYSSSSSSSSDSSSSSSDSEDEDKKQGKRRKKKKNRSHKSSESS 146 Query: 173 KKEATDITADSSSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDD 232 E + DS + ++ GT K K KK + S KP L E+ S + + ++ Sbjct: 147 MSETESDSKDSLKK--KKKSKDGTEKEKDIKGLSKKRKMYSEDKP-LSSESLSESEYIEE 203 Query: 233 SASSSSEESEERD--TKKTKRKK--------REKKAHTS 261 + + SEER+ T+KTK+KK ++KKA +S Sbjct: 204 VRAKKKKSSEEREKATEKTKKKKKHKKHSKKKKKKAASS 242 Score = 51.2 bits (121), Expect = 1e-06 Identities = 40/144 (27%), Positives = 67/144 (46%), Gaps = 5/144 (3%) Query: 146 ESRKHKKSKKS-HKKKQKKRSHKKQKKSKKEATDITADSSSEFSEETGASGTRKGKQPHK 204 E KH++ S + KKR KK++K K ++ SSS+ S + S KQ + Sbjct: 72 ELEKHREKLLSGSESSSKKRQRKKKEKKKSGRYSSSSSSSSDSSSSSSDSEDEDKKQGKR 131 Query: 205 RKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESE-ERDTKKTKRKKR---EKKAHT 260 RKKK + + E ES++ S S + +E E+D K +K++ E K + Sbjct: 132 RKKKKNRSHKSSESSMSETESDSKDSLKKKKKSKDGTEKEKDIKGLSKKRKMYSEDKPLS 191 Query: 261 SVANNEIQERTNKRTNWKVATDER 284 S + +E + R K +++ER Sbjct: 192 SESLSESEYIEEVRAKKKKSSEER 215 Score = 50.8 bits (120), Expect = 1e-06 Identities = 39/159 (24%), Positives = 73/159 (45%), Gaps = 9/159 (5%) Query: 134 KKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITADSSSEFSEETGA 193 + + P ++ + R + K +K+KK S K +E + E E Sbjct: 24 QSSGPTIQDYLNRPRPTWEEVKEQLEKKKKGS--KALAEFEEKMNENWKKELEKHREKLL 81 Query: 194 SGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEERDTKKTKRKK 253 SG+ + +RKKK +KKS + + S++S SD S+SSS E E++ K +RKK Sbjct: 82 SGSESSSKKRQRKKKEKKKSGRY------SSSSSSSSDSSSSSSDSEDEDKKQGK-RRKK 134 Query: 254 REKKAHTSVANNEIQERTNKRTNWKVATDERSAESSEDD 292 ++ ++H S ++ + ++ + + K + E D Sbjct: 135 KKNRSHKSSESSMSETESDSKDSLKKKKKSKDGTEKEKD 173 Score = 44.3 bits (103), Expect = 1e-04 Identities = 47/191 (24%), Positives = 76/191 (39%), Gaps = 15/191 (7%) Query: 25 QEESDMWKIRELEKQMEDAYRGTKRKMLPSSSSRMRSDGFDEESQRYYWRPKNEISGTLE 84 ++ ++ WK +ELEK E G++ SS R R ++S RY S + Sbjct: 63 EKMNENWK-KELEKHREKLLSGSES----SSKKRQRKKKEKKKSGRY------SSSSSSS 111 Query: 85 DDFLKAKSWNKKFYDYEANMPDRWGHSGYKELYPEEFETDSDQQDITNGKKTSPQVKSST 144 D + S ++ + + + +K ET+SD +D KK S K T Sbjct: 112 SDSSSSSSDSEDEDKKQGKRRKKKKNRSHKSSESSMSETESDSKDSLKKKKKS---KDGT 168 Query: 145 HESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITADSSSEFSEETGASGTRKGKQPHK 204 + + K K K + + + S+ E + + SEE T K K+ K Sbjct: 169 EKEKDIKGLSKKRKMYSEDKPLSSESLSESEYIEEVRAKKKKSSEER-EKATEKTKKKKK 227 Query: 205 RKKKSRKKSLK 215 KK S+KK K Sbjct: 228 HKKHSKKKKKK 238 >gi|4557509 cylicin 2 [Homo sapiens] Length = 348 Score = 58.2 bits (139), Expect = 9e-09 Identities = 64/252 (25%), Positives = 99/252 (39%), Gaps = 31/252 (12%) Query: 30 MWKIRELEKQME--DAYRGTKRKMLP--------SSSSRMRSDGFDEESQRYYWRPKNEI 79 +W R L + E Y +R+ L S ++ + G D+ +Q+ ++E+ Sbjct: 75 LWMYRSLMRISERPSVYLAARRQPLKPTRTVEVDSKAAEIGKKGEDKTTQKDTTDSESEL 134 Query: 80 SGTLEDDFLKAKSWNK-KFYDYEANMPDRWG----HSGYKELYPEEFETDSDQQDITNGK 134 +D K K K K +A + G G E E ++D K Sbjct: 135 KQGKKDS-KKGKDIEKGKEEKLDAKKDSKKGKKDAEKGKDSATESEDEKGGAKKDNKKDK 193 Query: 135 KTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITADSSSEFSEETGAS 194 K S + K S ES + +K +K K+ K KK K A ++ A + E +E G Sbjct: 194 KDSNKGKDSATES----EGEKGGTEKDSKKGKKDSKKGKDSAIELQAVKADEKKDEDGKK 249 Query: 195 GTRKGKQPHKRKK-----KSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEERDTKKT 249 KG + KK K KK KKP+ S S S D S++ +D KK Sbjct: 250 DANKGDESKDAKKDAKEIKKGKKDKKKPS------STDSDSKDDVKKESKKDATKDAKKV 303 Query: 250 KRKKREKKAHTS 261 +K EK++ S Sbjct: 304 AKKDTEKESADS 315 Score = 52.0 bits (123), Expect = 6e-07 Identities = 38/174 (21%), Positives = 79/174 (45%), Gaps = 10/174 (5%) Query: 128 QDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITADSSSEF 187 +DI GK+ K + + +K + K + + +K +KK+ D S Sbjct: 145 KDIEKGKEEKLDAKKDSKKGKKDAEKGKDSATESEDEKGGAKKDNKKDKKDSNKGKDSAT 204 Query: 188 SEETGASGTRK-GKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEERDT 246 E GT K K+ K KK + +++ A+ + + + D+ + ++D Sbjct: 205 ESEGEKGGTEKDSKKGKKDSKKGKDSAIELQAVKADEKKDEDGKKDANKGDESKDAKKDA 264 Query: 247 KKTKRKKREKKAHTSV---ANNEIQERTNK---RTNWKVA---TDERSAESSED 291 K+ K+ K++KK +S + +++++ + K + KVA T++ SA+S +D Sbjct: 265 KEIKKGKKDKKKPSSTDSDSKDDVKKESKKDATKDAKKVAKKDTEKESADSKKD 318 Score = 47.4 bits (111), Expect = 2e-05 Identities = 50/248 (20%), Positives = 100/248 (40%), Gaps = 41/248 (16%) Query: 18 TDAHNKIQE-ESDMWKIRELEKQMEDAYRGTKRKMLPSSSSRMRSDGFDEESQRYYWRPK 76 TD+ +++++ + D K +++EK E+ K + D E + Sbjct: 128 TDSESELKQGKKDSKKGKDIEKGKEEKLDAKKDSKKGKKDAEKGKDSATES--------E 179 Query: 77 NEISGTLEDDFLKAKSWNKKFYDYEANMPDRWGHSGYKELYPEEFETDSD----QQDITN 132 +E G +D+ K NK G E E+ T+ D ++D Sbjct: 180 DEKGGAKKDNKKDKKDSNK-------------GKDSATESEGEKGGTEKDSKKGKKDSKK 226 Query: 133 GKKTSPQVKSSTHESRKHKKSKKSHKK-------KQKKRSHKKQKKSKKEATDITADSSS 185 GK ++ ++++ + +K + KK K K+ + KK KK KK+ + +DS Sbjct: 227 GKDSAIELQAVKADEKKDEDGKKDANKGDESKDAKKDAKEIKKGKKDKKKPSSTDSDSKD 286 Query: 186 EFSEETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEERD 245 + +E+ T+ K+ K+ + KK A ++ A ++++ ++D Sbjct: 287 DVKKESKKDATKDAKKVAKKDTEKESADSKKDA--------KKNAKKDAKKDAKKNAKKD 338 Query: 246 TKKTKRKK 253 KK +KK Sbjct: 339 EKKDAKKK 346 >gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] Length = 245 Score = 56.2 bits (134), Expect = 3e-08 Identities = 33/145 (22%), Positives = 64/145 (44%), Gaps = 1/145 (0%) Query: 146 ESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITADSSSEFSEETGASGTRKGKQPHKR 205 ES + K+ ++ K+K+++ +K+++ KKE E + ++G++ KR Sbjct: 56 ESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEKEKR 115 Query: 206 KKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEERDTKKTKRKKREKKAHTSVANN 265 KKK +K+ + E E + + EER+ K+ +RK+R+K+ V Sbjct: 116 KKKEKKERGRTSKEGKERERKEERKREERKERERKKEERE-KERERKERKKRERKQVGEK 174 Query: 266 EIQERTNKRTNWKVATDERSAESSE 290 E + + +R K R E Sbjct: 175 EEERKEKERKERKKRERNRKERKKE 199 Score = 54.7 bits (130), Expect = 1e-07 Identities = 35/173 (20%), Positives = 78/173 (45%), Gaps = 4/173 (2%) Query: 122 ETDSDQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQKK-RSHKKQKKSKKEATDIT 180 E +S+++ ++ + + + + KK KK +KK+++ R ++++K KE + Sbjct: 54 ERESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEKE 113 Query: 181 ADSSSEFSEE--TGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSS 238 E E T G + ++ +++++ +++ KK E E + Sbjct: 114 KRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERKERKKRERKQVGE 173 Query: 239 EESEERDTKKTKRKKREKKAHTSVANNEIQERTNKRTNWKVATDERSAESSED 291 +E E ++ ++ +RKKRE+ E +ER ++ K +ER E +D Sbjct: 174 KEEERKEKERKERKKRERNRKERKKERERKERRERKKERK-KKEERKKERQKD 225 Score = 53.5 bits (127), Expect = 2e-07 Identities = 51/247 (20%), Positives = 99/247 (40%), Gaps = 52/247 (21%) Query: 32 KIRELEKQMEDAYRGTKRKMLPSSSSRMRSDGFDEESQRYYWRPKNEISGTLEDDFLKAK 91 +IRE E+++E G K + ES+R R + E K K Sbjct: 37 EIREREREIETRKEGKKER----------------ESERKKERRERE----------KRK 70 Query: 92 SWNKKFYDYEANMPDRWGHSGYKELYPEEFETDSDQQDITNGKKTSPQVKSSTHESRKHK 151 +K E ++ G +E ++ + + ++ +K + K R K Sbjct: 71 REREKERKRERGKKEKKGERKKEERERKKRRREKENKE--GEEKEKRKKKEKKERGRTSK 128 Query: 152 KSKKSHKKKQKKRSHKKQKKSKKEATDITADSSSEFSEETGASGTRKGKQPHKRKKKSRK 211 + K+ +K+++KR +K+++ KKE + E E + G++ +RK+K RK Sbjct: 129 EGKERERKEERKREERKERERKKE----EREKERERKERKKRERKQVGEKEEERKEKERK 184 Query: 212 KSLKKPALFLEAESNTSHSDDSASSSSEESEERDTKKTKRKKREKKAHTSVANNEIQERT 271 + K+ + E E R+ KK ++KK E+K + + Sbjct: 185 ERKKR-----------ERNRKERKKERERKERRERKKERKKKEERKK---------ERQK 224 Query: 272 NKRTNWK 278 +++TNW+ Sbjct: 225 DRQTNWR 231 Score = 50.1 bits (118), Expect = 2e-06 Identities = 36/175 (20%), Positives = 71/175 (40%), Gaps = 3/175 (1%) Query: 119 EEFETDSDQQDITNGKKTSPQVKSSTHESRKHKKS-KKSHKKKQKKRSHKKQKKSKKEAT 177 E E + +++ +K K E +K ++ KK ++K+ K +K+K+ KKE Sbjct: 62 ERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEKEKRKKKEKK 121 Query: 178 DITADSSSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSS 237 + S E R+ ++ +RKK+ R+K ++ ++ Sbjct: 122 ERGRTSKEGKERERKEERKREERKERERKKEEREKERERKERKKRERKQVGEKEEERKE- 180 Query: 238 SEESEERDTKKTKRKKREKKAHTSVANNEIQERTNKRTNWKVATDERSAESSEDD 292 +E +ER ++ RK+R+K+ +ER K K +R E + Sbjct: 181 -KERKERKKRERNRKERKKERERKERRERKKERKKKEERKKERQKDRQTNWREKE 234 Score = 46.2 bits (108), Expect = 3e-05 Identities = 35/149 (23%), Positives = 69/149 (46%), Gaps = 16/149 (10%) Query: 146 ESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITADSSSEFSEETGASGTRKGKQPHKR 205 E+RK K ++ ++K+++R +K+K+ +++ E E G + ++ +R Sbjct: 46 ETRKEGKKERESERKKERREREKRKREREK----------ERKRERGKKEKKGERKKEER 95 Query: 206 KKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEER----DTKKTKRKKREKKAHTS 261 ++K R++ K+ E E +S+E +ER + K+ +RK+RE+K Sbjct: 96 ERKKRRRE-KENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEER 154 Query: 262 VANNEIQERTNKRTNWKVATDERSAESSE 290 E +ER KR +V E + E Sbjct: 155 EKERERKER-KKRERKQVGEKEEERKEKE 182 Score = 38.1 bits (87), Expect = 0.009 Identities = 38/199 (19%), Positives = 85/199 (42%), Gaps = 10/199 (5%) Query: 16 RHTDAHNKIQEESDMWKIRELEKQMEDAYRGTK--RKMLPSSSSRMRSDGFDEESQRYYW 73 R ++ + +E + RE E++ E + K RK + R + ++E + Sbjct: 55 RESERKKERREREKRKREREKERKRERGKKEKKGERKKEERERKKRRREKENKEGEEKEK 114 Query: 74 RPKNEISGTLEDDFLKAKSWNKKFYDYEANMPDRWGHSGYKELYPEEFETDSDQQDITNG 133 R K E ++ +K ++ E +R KE E E + ++ Sbjct: 115 RKKKE----KKERGRTSKEGKERERKEERKREERKERERKKE--EREKERERKERKKRER 168 Query: 134 KKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITADSSSEFSEETGA 193 K+ + + + RK +K ++ ++K++KK +K+++ +K+ + E ++ Sbjct: 169 KQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKKEERKKERQKDRQT 228 Query: 194 SGTRKGKQPHKRKKKSRKK 212 + + K+ KR++K RKK Sbjct: 229 NW--REKERGKRERKERKK 245 >gi|239749449 PREDICTED: hypothetical protein [Homo sapiens] Length = 275 Score = 54.7 bits (130), Expect = 1e-07 Identities = 38/147 (25%), Positives = 62/147 (42%), Gaps = 24/147 (16%) Query: 146 ESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITADSSSEFSEETGASGTRKGKQPHKR 205 E RK KK KK ++KQ+ R +K+KK +KE R+ KQ +R Sbjct: 93 ERRKRKKEKKKRERKQRGRRERKKKKERKERE-------------------RENKQRRER 133 Query: 206 KKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEERDTKKTK-RKKREKKAHTSVAN 264 K+K R+K ++ E + + EER+ K+ + RK+R+K+ Sbjct: 134 KRKKRRKKKRRK----ERKREKERGKRERKRKKRKKEEREKKRERNRKERKKERERKERR 189 Query: 265 NEIQERTNKRTNWKVATDERSAESSED 291 +ER +R K +R + D Sbjct: 190 ERKKERKKERRKKKERKKDRKTDRQTD 216 Score = 53.1 bits (126), Expect = 3e-07 Identities = 34/173 (19%), Positives = 74/173 (42%), Gaps = 6/173 (3%) Query: 120 EFETDSDQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDI 179 + T+ ++ K Q +S + R+ ++ +K ++K++KR K++K K++ + Sbjct: 12 KLNTELQMVSCSHISKPCTQRESERKKERREREKRKREREKERKRERGKKEKKKRKKRER 71 Query: 180 TADSSSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSE 239 + + E R+ K+ KRKK+ +K+ K+ + E Sbjct: 72 GKERERKRKEREKQRKERREKERRKRKKEKKKRERKQ-----RGRRERKKKKERKERERE 126 Query: 240 ESEERDTKKTKRKKREKKAHTSVANNEIQERTNKRTNWKVATDERSAESSEDD 292 + R+ K+ KR+K++++ E +R KR K E+ E + + Sbjct: 127 NKQRRERKRKKRRKKKRRKERK-REKERGKRERKRKKRKKEEREKKRERNRKE 178 Score = 53.1 bits (126), Expect = 3e-07 Identities = 34/156 (21%), Positives = 67/156 (42%), Gaps = 17/156 (10%) Query: 134 KKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITADSSSEFSEETGA 193 K+ + + ++ +K KK KK+++K+ ++++K KKE + Sbjct: 78 KRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKE--------------- 122 Query: 194 SGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEERD-TKKTKRK 252 R+ KQ +RK+K R+K ++ E E E ++R+ +K ++K Sbjct: 123 -RERENKQRRERKRKKRRKKKRRKERKREKERGKRERKRKKRKKEEREKKRERNRKERKK 181 Query: 253 KREKKAHTSVANNEIQERTNKRTNWKVATDERSAES 288 +RE+K +ER K+ K +R +S Sbjct: 182 ERERKERRERKKERKKERRKKKERKKDRKTDRQTDS 217 Score = 47.8 bits (112), Expect = 1e-05 Identities = 28/125 (22%), Positives = 56/125 (44%), Gaps = 28/125 (22%) Query: 133 GKKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITADSSSEFSEETG 192 G++ + K R++K+ ++ +KK++K+ +K++K +KE Sbjct: 110 GRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKE----------------- 152 Query: 193 ASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEERDTKKTKRK 252 +GK+ KRKK+ +++ KK E N +++ KK +RK Sbjct: 153 -----RGKRERKRKKRKKEEREKK------RERNRKERKKERERKERRERKKERKKERRK 201 Query: 253 KREKK 257 K+E+K Sbjct: 202 KKERK 206 Score = 43.9 bits (102), Expect = 2e-04 Identities = 43/192 (22%), Positives = 76/192 (39%), Gaps = 13/192 (6%) Query: 25 QEESDMWKIR-ELEKQMEDAYRGTKRKMLPSSSSRMRSDGFDEESQRYYWRPKNEISGTL 83 Q ES+ K R E EK+ + + KR+ + + +E +R + + Sbjct: 31 QRESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERR 90 Query: 84 EDDFLKAKSWNKKFYDYEANMPDRWGHSGYKELYPEEFETDSDQQDITNGKKTSPQVKSS 143 E + K K KK + +R KE E + ++ KK + K Sbjct: 91 EKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKRE 150 Query: 144 THESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITADSSSEFSEETGASGTRKGKQPH 203 ++ +K KK K++++K+ + +K+ KKE E +K ++ Sbjct: 151 KERGKRERKRKKRKKEEREKKRERNRKERKKE------------RERKERRERKKERKKE 198 Query: 204 KRKKKSRKKSLK 215 +RKKK RKK K Sbjct: 199 RRKKKERKKDRK 210 Score = 43.9 bits (102), Expect = 2e-04 Identities = 33/180 (18%), Positives = 74/180 (41%), Gaps = 8/180 (4%) Query: 120 EFETDSDQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDI 179 E E ++++ K+ + + ++ KK KK + K+++R K+++K +KE + Sbjct: 33 ESERKKERREREKRKREREKERKRERGKKEKKKRKKRERGKERERKRKEREKQRKERREK 92 Query: 180 TADSSSEFSE--ETGASGTRKGKQPHKRK------KKSRKKSLKKPALFLEAESNTSHSD 231 + + E G R+ K+ +RK K+ R++ KK + + Sbjct: 93 ERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKKRRKKKRRKERKREKE 152 Query: 232 DSASSSSEESEERDTKKTKRKKREKKAHTSVANNEIQERTNKRTNWKVATDERSAESSED 291 + +++ ++ KR++ K+ E +ER +R + ER + D Sbjct: 153 RGKRERKRKKRKKEEREKKRERNRKERKKERERKERRERKKERKKERRKKKERKKDRKTD 212 Score = 32.3 bits (72), Expect = 0.51 Identities = 27/144 (18%), Positives = 57/144 (39%), Gaps = 3/144 (2%) Query: 32 KIRELEKQMEDAYRGTKRKMLPSSSSRMRSDGFDEESQRYYWRPKNEISGTLEDDFLKAK 91 K +E EKQ ++ +RK R R E ++ R + E + + K Sbjct: 78 KRKEREKQRKERREKERRKRKKEKKKRERKQRGRRERKKKKERKERERENKQRRERKRKK 137 Query: 92 SWNKKFYDYEANMPDRWGHSGYKELYPEEFETDSDQQDITNGKKTSPQVKSSTHESRKHK 151 KK +R ++ +E + +++ N K+ + + RK + Sbjct: 138 RRKKKRRKERKREKERGKRERKRKKRKKE---EREKKRERNRKERKKERERKERRERKKE 194 Query: 152 KSKKSHKKKQKKRSHKKQKKSKKE 175 + K+ KKK++K+ K +++ + Sbjct: 195 RKKERRKKKERKKDRKTDRQTDSQ 218 >gi|42560244 peptidylprolyl isomerase G [Homo sapiens] Length = 754 Score = 54.7 bits (130), Expect = 1e-07 Identities = 51/276 (18%), Positives = 112/276 (40%), Gaps = 24/276 (8%) Query: 26 EESDMWKIRELEKQMEDAYRGTKRKMLPSSSSRMRSDGFDEESQRYYWRPKNEISGTLED 85 +E D R EK+M +G + + + S G D+E R + K S + E Sbjct: 471 KERDSKHNRNEEKRMRSRSKGRDHENVKEKEKQSDSKGKDQERSRSKEKSKQLESKSNEH 530 Query: 86 DFLKAKSWNKKFYDYEANMPDRWGHSGYKELYPEEFETDSDQQDITNGKKTSPQVKSSTH 145 D K+K +++ G Y +S ++ + + S +V+S TH Sbjct: 531 DHSKSKEKDRRAQSRSRECDITKGKHSY----------NSRTRERSRSRDRSRRVRSRTH 580 Query: 146 ESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITADSS---------SEFSEETGASGT 196 + R +SK+ H+ ++++ + + +S++ T S S SE + Sbjct: 581 D-RDRSRSKEYHRYREQEYRRRGRSRSRERRTPPGRSRSKDRRRRRRDSRSSEREESQSR 639 Query: 197 RKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEERDTKKTKRKKREK 256 K K ++ K S +K + + ++S +S +++ + ++ K K+ ++ Sbjct: 640 NKDKYRNQESKSSHRKENSESEKRMYSKSRDHNSSNNSREKKADRDQSPFSKIKQSSQDN 699 Query: 257 KAHTSVANNEIQERTNKRTNWKVATDERSAESSEDD 292 + +S+ N+ E+ V + + ++ E+D Sbjct: 700 ELKSSMLKNKEDEKIRS----SVEKENQKSKGQEND 731 Score = 48.1 bits (113), Expect = 9e-06 Identities = 33/137 (24%), Positives = 60/137 (43%), Gaps = 25/137 (18%) Query: 155 KSHKKKQKKRSHKKQKKSKKEATDITADSSSEFSEETGASGT-------------RKGKQ 201 KS KK++K+ HK S ++D + S S+ S ++ S + RK + Sbjct: 180 KSKVKKEEKKRHKSSSSSSSSSSDSDSSSDSQSSSDSSDSESATEEKSKKRKKKHRKNSR 239 Query: 202 PHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSS------------EESEERDTKKT 249 HK++KK RKKS K + EAE+ + + + + D K+ Sbjct: 240 KHKKEKKKRKKSKKSASSESEAENLEAQPQSTVRPEEIPPIPENRFLMRKSPPKADEKER 299 Query: 250 KRKKREKKAHTSVANNE 266 K ++RE++ + N++ Sbjct: 300 KNRERERERECNPPNSQ 316 Score = 45.4 bits (106), Expect = 6e-05 Identities = 34/99 (34%), Positives = 49/99 (49%), Gaps = 6/99 (6%) Query: 154 KKSHKKKQKKRSHKKQKKSKKEATDITADSSSEFSEETGASGTRKGKQPHKRKKKSRKKS 213 K KK++KKR HK S ++D + S S+ S ++ S + ++ KRKKK RK S Sbjct: 180 KSKVKKEEKKR-HKSSSSSSSSSSDSDSSSDSQSSSDSSDSESATEEKSKKRKKKHRKNS 238 Query: 214 LKKPALFLEAESNTSHSDDSASSSSE-ESEERDTKKTKR 251 K + + S SASS SE E+ E + T R Sbjct: 239 RKHK----KEKKKRKKSKKSASSESEAENLEAQPQSTVR 273 Score = 43.9 bits (102), Expect = 2e-04 Identities = 29/89 (32%), Positives = 45/89 (50%), Gaps = 2/89 (2%) Query: 202 PHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEERDTKKTKRKKREKKAHTS 261 P + KK KK K + + S++ S DS SSS E T++ K KKR+KK H Sbjct: 179 PKSKVKKEEKKRHKSSSSSSSSSSDSDSSSDSQSSSDSSDSESATEE-KSKKRKKK-HRK 236 Query: 262 VANNEIQERTNKRTNWKVATDERSAESSE 290 + +E+ ++ + K A+ E AE+ E Sbjct: 237 NSRKHKKEKKKRKKSKKSASSESEAENLE 265 Score = 42.0 bits (97), Expect = 6e-04 Identities = 37/123 (30%), Positives = 56/123 (45%), Gaps = 16/123 (13%) Query: 123 TDSDQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKK--KQKKRSHKKQKKSKKEATDIT 180 +DSD + S +S+T E K KK KK H+K ++ K+ KK+KKSKK A + Sbjct: 202 SDSDSSSDSQSSSDSSDSESATEE--KSKKRKKKHRKNSRKHKKEKKKRKKSKKSA---S 256 Query: 181 ADSSSEFSEETGASGTRKGKQP---------HKRKKKSRKKSLKKPALFLEAESNTSHSD 231 ++S +E E S R + P K K+ +K K E E N +S Sbjct: 257 SESEAENLEAQPQSTVRPEEIPPIPENRFLMRKSPPKADEKERKNRERERERECNPPNSQ 316 Query: 232 DSA 234 ++ Sbjct: 317 PAS 319 Score = 39.7 bits (91), Expect = 0.003 Identities = 57/300 (19%), Positives = 114/300 (38%), Gaps = 31/300 (10%) Query: 18 TDAHNKIQEESDMWKIRELEKQMEDAYRGTKRKMLPSSSSRMRSDGFDEESQRYYWRPKN 77 +D+ + +E+S K + + + KRK S+S S+ + E+Q Sbjct: 217 SDSESATEEKSKKRKKKHRKNSRKHKKEKKKRKKSKKSASS-ESEAENLEAQPQSTVRPE 275 Query: 78 EISGTLEDDFLKAKSWNK----------KFYDYEANMPDRWGHSGYKELYPEEFETDSDQ 127 EI E+ FL KS K + + E N P+ S + L T S + Sbjct: 276 EIPPIPENRFLMRKSPPKADEKERKNRERERERECNPPNSQPASYQRRL----LVTRSGR 331 Query: 128 QDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQ--------KKSKKEATDI 179 + G + S R + H +++ +R+ + + K K E +I Sbjct: 332 KIKGRGPRRYRTPSRSRSRDRFRRSETPPHWRQEMQRAQRMRVSSGERWIKGDKSELNEI 391 Query: 180 TADSSS-------EFSEETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDD 232 + S + ++ S + K ++K K K + K+ + +E + + + Sbjct: 392 KENQRSPVRVKERKITDHRNVSESPNRKNEKEKKVKDHKSNSKERDIRRNSEKDDKYKNK 451 Query: 233 SASSSSEESEERDTKKTKRKKREKKAHTSVANNEIQERTNKRTNWKVATDERSAESSEDD 292 + +S + +K+K K+R+ K H ++ R+ R + V E+ ++S D Sbjct: 452 VKKRAKSKSRSKSKEKSKSKERDSK-HNRNEEKRMRSRSKGRDHENVKEKEKQSDSKGKD 510 Score = 39.7 bits (91), Expect = 0.003 Identities = 39/172 (22%), Positives = 70/172 (40%), Gaps = 15/172 (8%) Query: 123 TDSDQQDITNGKKTSPQVKSSTHESRKHKKS--KKSHKKKQKKRSHKK------QKKSKK 174 TD + +K + K H+S ++ + S K + K KK + KSK+ Sbjct: 407 TDHRNVSESPNRKNEKEKKVKDHKSNSKERDIRRNSEKDDKYKNKVKKRAKSKSRSKSKE 466 Query: 175 EATDITADSSSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSA 234 ++ DS +EE KG+ H+ K+ K+S K + S S + + Sbjct: 467 KSKSKERDSKHNRNEEKRMRSRSKGRD-HENVKEKEKQSDSK-----GKDQERSRSKEKS 520 Query: 235 SSSSEESEERDTKKTKRKKREKKAHTSVAN-NEIQERTNKRTNWKVATDERS 285 +S E D K+K K R ++ + + + + N RT + + +RS Sbjct: 521 KQLESKSNEHDHSKSKEKDRRAQSRSRECDITKGKHSYNSRTRERSRSRDRS 572 Score = 38.1 bits (87), Expect = 0.009 Identities = 47/270 (17%), Positives = 99/270 (36%), Gaps = 52/270 (19%) Query: 69 QRYYWRPKNEISGTLEDDFLKAKSWNKKFYDYEANMPDRWGHSGYKELYPEEFETDSDQQ 128 +R+ K+E++ E+ + +K D+ N+ + KE ++ +++S ++ Sbjct: 378 ERWIKGDKSELNEIKENQRSPVRVKERKITDHR-NVSESPNRKNEKEKKVKDHKSNSKER 436 Query: 129 DITNGKKTSPQVKSSTHESRKHK-KSKKSHKKKQKKRSHK-------------------- 167 DI + + K+ + K K +SK K K K+R K Sbjct: 437 DIRRNSEKDDKYKNKVKKRAKSKSRSKSKEKSKSKERDSKHNRNEEKRMRSRSKGRDHEN 496 Query: 168 ---KQKKSKKEATDITADSSSEFSEETGASGTR-----------------------KGKQ 201 K+K+S + D S E S++ + KGK Sbjct: 497 VKEKEKQSDSKGKDQERSRSKEKSKQLESKSNEHDHSKSKEKDRRAQSRSRECDITKGKH 556 Query: 202 PHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEERDTKKTKRKKREKKAHTS 261 + + + R +S + S T D S S E++ ++ + + R ++ T Sbjct: 557 SYNSRTRERSRSRDRSR---RVRSRTHDRDRSRSKEYHRYREQEYRR-RGRSRSRERRTP 612 Query: 262 VANNEIQERTNKRTNWKVATDERSAESSED 291 + ++R +R + + + E S ++D Sbjct: 613 PGRSRSKDRRRRRRDSRSSEREESQSRNKD 642 Score = 35.8 bits (81), Expect = 0.046 Identities = 22/77 (28%), Positives = 36/77 (46%), Gaps = 2/77 (2%) Query: 114 KELYPEEFETDSDQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSK 173 K+ + + S D + + SS ES +KSKK +KK+ +++ +K KK K Sbjct: 188 KKRHKSSSSSSSSSSDSDSSSDSQSSSDSSDSESATEEKSKK--RKKKHRKNSRKHKKEK 245 Query: 174 KEATDITADSSSEFSEE 190 K+ +SSE E Sbjct: 246 KKRKKSKKSASSESEAE 262 >gi|40068059 CBF1 interacting corepressor [Homo sapiens] Length = 450 Score = 54.3 bits (129), Expect = 1e-07 Identities = 44/182 (24%), Positives = 81/182 (44%), Gaps = 7/182 (3%) Query: 114 KELYPEEFETDSDQQ---DITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQK 170 +E E E D + + +T +K K E +K KK +K K ++ + HKK K Sbjct: 197 QEYVASEGEEDPEVEFLKSLTTKQKQKLLRKLDRLEKKKKKKDRKKKKFQKSRSKHKKHK 256 Query: 171 KSKKEATDITADSSSEFSEETGAS-GTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSH 229 S ++ ++ SS+E SE + S K K+ ++K+K K S + E + + Sbjct: 257 SSSSSSSSSSSSSSTETSESSSESESNNKEKKIQRKKRKKNKCSGHNNSDSEEKDKSKKR 316 Query: 230 SDDSASSSSEESEERDTKKTKRKKREKKAHTSV---ANNEIQERTNKRTNWKVATDERSA 286 SSS + E+ +K + K E S ++++ + RT+K + K ++ + Sbjct: 317 KLHEELSSSHHNREKAKEKPRFLKHESSREDSKWSHSDSDKKSRTHKHSPEKRGSERKEG 376 Query: 287 ES 288 S Sbjct: 377 SS 378 Score = 45.4 bits (106), Expect = 6e-05 Identities = 30/97 (30%), Positives = 48/97 (49%), Gaps = 2/97 (2%) Query: 197 RKGKQPHKRKK--KSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEERDTKKTKRKKR 254 +K K+ K+KK KSR K K + + S++S S S SS ESE + +K ++K+ Sbjct: 234 KKKKKDRKKKKFQKSRSKHKKHKSSSSSSSSSSSSSSTETSESSSESESNNKEKKIQRKK 293 Query: 255 EKKAHTSVANNEIQERTNKRTNWKVATDERSAESSED 291 KK S NN E +K K+ + S+ + + Sbjct: 294 RKKNKCSGHNNSDSEEKDKSKKRKLHEELSSSHHNRE 330 Score = 44.3 bits (103), Expect = 1e-04 Identities = 56/261 (21%), Positives = 101/261 (38%), Gaps = 38/261 (14%) Query: 12 RNVIRHTDAHNKIQEESDMWKIRELEKQMEDAYRGTKRKMLPSSSSRMRSDGFDEESQRY 71 + ++R D K +++ D R+ +K + + K K SSSS S E S Sbjct: 222 QKLLRKLDRLEKKKKKKD----RKKKKFQKSRSKHKKHKSSSSSSSSSSSSSSTETS--- 274 Query: 72 YWRPKNEISGTLEDDFLKAKSWNKKFYDYEANMPDRWGHSGYKELYPEEFETDSDQQDIT 131 E S E + + K KK + + GH+ +DS+++D + Sbjct: 275 ------ESSSESESNNKEKKIQRKKRKKNKCS-----GHNN----------SDSEEKDKS 313 Query: 132 NGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITADSSSEFSEET 191 +K ++ SS+H +R+ K K K + R K S + T S E + Sbjct: 314 KKRKLHEEL-SSSHHNREKAKEKPRFLKHESSREDSKWSHSDSDKKSRTHKHSPE---KR 369 Query: 192 GASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEER----DTK 247 G+ + H R+++SR+ + P + + E+ + S ++ R D Sbjct: 370 GSERKEGSSRSHGREERSRRSRSRSPGSYKQRETRKRAQRNPGEEQSRRNDSRSHGTDLY 429 Query: 248 KTKRKKREKK--AHTSVANNE 266 + ++ RE HT V E Sbjct: 430 RGEKMYREHPGGTHTKVTQRE 450 >gi|239508778 PREDICTED: hypothetical protein, partial [Homo sapiens] Length = 123 Score = 54.3 bits (129), Expect = 1e-07 Identities = 29/103 (28%), Positives = 55/103 (53%), Gaps = 5/103 (4%) Query: 119 EEFETDSDQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATD 178 EE E + +++ K+ + K T E+ K K+ ++ KK+++KR KK+++ ++E + Sbjct: 21 EEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKRKKKKEEEEREEEEE 80 Query: 179 ITADSSSEFSEETGASGTRKGKQPHK-----RKKKSRKKSLKK 216 + E +E G +K K+ K +KKK R+K+ KK Sbjct: 81 EEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRRKTKKK 123 Score = 53.9 bits (128), Expect = 2e-07 Identities = 34/125 (27%), Positives = 56/125 (44%), Gaps = 15/125 (12%) Query: 167 KKQKKSKKEATDITADSSSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAE-- 224 KK+KK KKE + + + E EE G RK K+ KRK+K +KK K+ E E Sbjct: 1 KKKKKKKKETEE--TEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEKEEE 58 Query: 225 -----------SNTSHSDDSASSSSEESEERDTKKTKRKKREKKAHTSVANNEIQERTNK 273 ++ EE EE + ++ +R+K++KK E +++ + Sbjct: 59 EKKRKRKRKKKKEEEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKEEEEEKKKKRRR 118 Query: 274 RTNWK 278 +T K Sbjct: 119 KTKKK 123 Score = 53.9 bits (128), Expect = 2e-07 Identities = 32/141 (22%), Positives = 63/141 (44%), Gaps = 20/141 (14%) Query: 134 KKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITADSSSEFSEETGA 193 KK + T E+ + ++ ++ K+++KR K+++K KK+ T T Sbjct: 3 KKKKKKETEETEETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETE------------ 50 Query: 194 SGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEERDTKKTKRKK 253 RK K+ ++K+K ++K K E E ++ EE +E ++ K+KK Sbjct: 51 --KRKEKEEEEKKRKRKRKKKK------EEEEREEEEEEEEEEKEEEEKEEGRRRKKKKK 102 Query: 254 REKKAHTSVANNEIQERTNKR 274 R +K + + +T K+ Sbjct: 103 RRRKEEEEEKKKKRRRKTKKK 123 Score = 51.6 bits (122), Expect = 8e-07 Identities = 35/144 (24%), Positives = 66/144 (45%), Gaps = 28/144 (19%) Query: 114 KELYPEEFETDSDQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSK 173 KE E ++++++ GK+ + K E K KK+K++ K+K+K+ KK+K+ + Sbjct: 8 KETEETEETEETEEEEEKEGKRKEKR-KEKRKEKEKKKKTKETEKRKEKEEEEKKRKRKR 66 Query: 174 KEATDITADSSSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDS 233 K+ + + E EE + K+ +R+KK +K+ K+ Sbjct: 67 KKKKE--EEEREEEEEEEEEEKEEEEKEEGRRRKKKKKRRRKE----------------- 107 Query: 234 ASSSSEESEERDTKKTKRKKREKK 257 EE + KK +R+K +KK Sbjct: 108 --------EEEEKKKKRRRKTKKK 123 Score = 34.3 bits (77), Expect = 0.13 Identities = 17/88 (19%), Positives = 40/88 (45%), Gaps = 5/88 (5%) Query: 205 RKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEERDTKKTKRKKREKKAHTSVAN 264 +KKK +KK ++ E+ + ++ +E + K+ ++KK+ K+ Sbjct: 1 KKKKKKKKETEETE-----ETEETEEEEEKEGKRKEKRKEKRKEKEKKKKTKETEKRKEK 55 Query: 265 NEIQERTNKRTNWKVATDERSAESSEDD 292 E +++ ++ K +ER E E++ Sbjct: 56 EEEEKKRKRKRKKKKEEEEREEEEEEEE 83 >gi|151301228 formin binding protein 3 [Homo sapiens] Length = 930 Score = 54.3 bits (129), Expect = 1e-07 Identities = 39/149 (26%), Positives = 68/149 (45%), Gaps = 20/149 (13%) Query: 145 HESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITADSSS----EFSEETGA---SGTR 197 HE + H K H KK KK H+K+ +S+ + DS S + SE A S + Sbjct: 775 HECQHHHSKNKKHSKKSKKH-HRKRSRSRSGSDSDDDDSHSKKKRQRSESRSASEHSSSA 833 Query: 198 KGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEERDTKKTKRKKREKK 257 + ++ +K+ KK +KKS K+ H DS S +E +++ K + +K + Sbjct: 834 ESERSYKKSKKHKKKSKKR-----------RHKSDSPESDAEREKDKKEKDRESEKDRTR 882 Query: 258 AHTSVANNEIQERTNKRT-NWKVATDERS 285 + + +++T K + NW + E S Sbjct: 883 QRSESKHKSPKKKTGKDSGNWDTSGSELS 911 Score = 54.3 bits (129), Expect = 1e-07 Identities = 37/135 (27%), Positives = 62/135 (45%), Gaps = 16/135 (11%) Query: 146 ESRKH-KKSKKSHKKKQKKRS---------HKKQKKSKKEATDITADSSSEFSEETGASG 195 +++KH KKSKK H+K+ + RS H K+K+ + E+ + SSS SE + Sbjct: 783 KNKKHSKKSKKHHRKRSRSRSGSDSDDDDSHSKKKRQRSESRSASEHSSSAESERS---- 838 Query: 196 TRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSD-DSASSSSEESEERDTKKTKRKKR 254 K + HK+K K R+ P E E + D +S + + E K K+K Sbjct: 839 -YKKSKKHKKKSKKRRHKSDSPESDAEREKDKKEKDRESEKDRTRQRSESKHKSPKKKTG 897 Query: 255 EKKAHTSVANNEIQE 269 + + + +E+ E Sbjct: 898 KDSGNWDTSGSELSE 912 Score = 47.0 bits (110), Expect = 2e-05 Identities = 52/238 (21%), Positives = 98/238 (41%), Gaps = 26/238 (10%) Query: 20 AHNKIQEESDMWKIRELEKQMEDAYRGTKRK------MLPSSSSRMRSDGFDEESQRYYW 73 A N + E+++ RE E++ E+A R KRK ML ++ + D E+ + + Sbjct: 693 AFNSLLEKAEA---REREREKEEA-RKMKRKESAFKSMLKQAAPPIELDAVWEDIRERFV 748 Query: 74 RPKNEISGTLED-------DFLKAKSWNKKFYDYEANMPDRWGHSGYKELYPEEFETDSD 126 + TLE DF+ + + + + +++ +DSD Sbjct: 749 KEPAFEDITLESERKRIFKDFMHVLEHECQHHHSKNKKHSKKSKKHHRKRSRSRSGSDSD 808 Query: 127 QQDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITADSSSE 186 D + KK S E +S++S+KK +K + K+++ K ++ + A+ + Sbjct: 809 DDDSHSKKKRQRSESRSASEHSSSAESERSYKKSKKHKKKSKKRRHKSDSPESDAEREKD 868 Query: 187 FSEETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEER 244 E+ S + +Q + K KS KK K ++ + D S S SE E+ Sbjct: 869 KKEKDRESEKDRTRQRSESKHKSPKKKTGK---------DSGNWDTSGSELSEGELEK 917 Score = 33.5 bits (75), Expect = 0.23 Identities = 38/173 (21%), Positives = 66/173 (38%), Gaps = 38/173 (21%) Query: 146 ESRKHKKSKKSHKKKQKK----RSHKKQKKSKKEATDITADSSSEFSEETG-----ASGT 196 E+R+ ++ K+ +K ++K +S KQ E + D F +E Sbjct: 702 EAREREREKEEARKMKRKESAFKSMLKQAAPPIELDAVWEDIRERFVKEPAFEDITLESE 761 Query: 197 RKG-------------KQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEE 243 RK + H + KK KKS K H S S S +S++ Sbjct: 762 RKRIFKDFMHVLEHECQHHHSKNKKHSKKSKKH------------HRKRSRSRSGSDSDD 809 Query: 244 RDTKKTKRKKREKKA----HTSVANNEIQERTNKRTNWKVATDERSAESSEDD 292 D+ K+++R + H+S A +E + +K+ K ++S E D Sbjct: 810 DDSHSKKKRQRSESRSASEHSSSAESERSYKKSKKHKKKSKKRRHKSDSPESD 862 Score = 33.5 bits (75), Expect = 0.23 Identities = 20/91 (21%), Positives = 37/91 (40%) Query: 201 QPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEERDTKKTKRKKREKKAHT 260 Q H K K K KK + S SDD S S ++ + +++ ++ Sbjct: 778 QHHHSKNKKHSKKSKKHHRKRSRSRSGSDSDDDDSHSKKKRQRSESRSASEHSSSAESER 837 Query: 261 SVANNEIQERTNKRTNWKVATDERSAESSED 291 S ++ ++ +K+ K + E AE +D Sbjct: 838 SYKKSKKHKKKSKKRRHKSDSPESDAEREKD 868 >gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo sapiens] Length = 434 Score = 54.3 bits (129), Expect = 1e-07 Identities = 40/190 (21%), Positives = 76/190 (40%), Gaps = 18/190 (9%) Query: 116 LYPEEFETDSDQQDITNGKKTSPQV----------------KSSTHESRKHKKSKKSHKK 159 L PE+ D D++ + SP+ + S +E RKH+ +S + Sbjct: 11 LAPEKTSPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSRSRSKEG 70 Query: 160 KQKKRSHKKQKKSKKEATDITADSSSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPAL 219 ++ + K KK K E + SS + E +S G+ HKRK++ + Sbjct: 71 RRHESKDKSSKKHKSEEHNDKEHSSDKGRERLNSS--ENGEDRHKRKERKSSRGRSHSRS 128 Query: 220 FLEAESNTSHSDDSASSSSEESEERDTKKTKRKKREKKAHTSVANNEIQERTNKRTNWKV 279 + S S + S S E + ++ R++++ ++ + I+ R+ R+ + Sbjct: 129 RSRERRHRSRSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRH 188 Query: 280 ATDERSAESS 289 T RS S Sbjct: 189 RTRSRSRTRS 198 Score = 42.7 bits (99), Expect = 4e-04 Identities = 32/134 (23%), Positives = 56/134 (41%), Gaps = 14/134 (10%) Query: 135 KTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITADSSSEFSEETGAS 194 K+S + KS H ++H K + + + K+ +++++ + S S E S Sbjct: 78 KSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRERRHRS 137 Query: 195 GTRKGKQPHKR-------------KKKSRKKSL-KKPALFLEAESNTSHSDDSASSSSEE 240 +R+ K+ R +KKSR +S +K + + S + H + S S Sbjct: 138 RSRERKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRTR 197 Query: 241 SEERDTKKTKRKKR 254 S RD KK K R Sbjct: 198 SRSRDRKKRIEKPR 211 >gi|50409756 SRp25 nuclear protein isoform 1 [Homo sapiens] Length = 360 Score = 53.1 bits (126), Expect = 3e-07 Identities = 31/111 (27%), Positives = 63/111 (56%), Gaps = 4/111 (3%) Query: 151 KKSKKSHKKKQKKRSHKKQKKSKKEATDITADSSSEFSEETGASGTRKGKQP---HKRKK 207 +K +S + + + S K++KKS+K+ + + S+S+ + + A G P + K+ Sbjct: 130 RKRSRSRSRSRGRGSEKRKKKSRKDTSRNCSASTSQGRKASTAPGAEASPSPCITERSKQ 189 Query: 208 KSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEERDTK-KTKRKKREKK 257 K+R+++ + + S++S S S+SSSS + ++ K K KR+K++KK Sbjct: 190 KARRRTRSSSSSSSSSSSSSSSSSSSSSSSSSDGRKKRGKYKDKRRKKKKK 240 Score = 38.5 bits (88), Expect = 0.007 Identities = 38/147 (25%), Positives = 62/147 (42%), Gaps = 19/147 (12%) Query: 125 SDQQDITNGKKTSPQVKSSTHESRKHKKSKKSH---------KKKQKKRSHKKQKKSKKE 175 S+++ + K TS +ST + RK + + + KQK R + S Sbjct: 144 SEKRKKKSRKDTSRNCSASTSQGRKASTAPGAEASPSPCITERSKQKARRRTRSSSSSSS 203 Query: 176 ATDITADSSSEFSEETGASGTRK-GKQPHKRKKKSRKKSLKK-------PALFLEAESNT 227 ++ ++ SSS S + + G +K GK KR+KK KK KK A + E+ Sbjct: 204 SSSSSSSSSSSSSSSSSSDGRKKRGKYKDKRRKK--KKKRKKLKKKGKEKAEAQQVEALP 261 Query: 228 SHSDDSASSSSEESEERDTKKTKRKKR 254 S D S+ E E+ ++K R Sbjct: 262 GPSLDQWHRSAGEEEDGPVLTDEQKSR 288 Score = 38.1 bits (87), Expect = 0.009 Identities = 31/152 (20%), Positives = 61/152 (40%), Gaps = 9/152 (5%) Query: 123 TDSDQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITAD 182 + S ++ +S SS ++ K K KKK+K++ KK+ K K EA + A Sbjct: 201 SSSSSSSSSSSSSSSSSSSSSDGRKKRGKYKDKRRKKKKKRKKLKKKGKEKAEAQQVEAL 260 Query: 183 SSSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESE 242 + ++G + ++KSR +++K T D+ S + Sbjct: 261 PGPSLDQWHRSAGEEEDGPVLTDEQKSRIQAMK---------PMTKEEWDARQSIIRKVV 311 Query: 243 ERDTKKTKRKKREKKAHTSVANNEIQERTNKR 274 + +T +T+ K + + + E NK+ Sbjct: 312 DPETGRTRLIKGDGEVLEEIVTKERHREINKQ 343 >gi|116089325 splicing factor, arginine/serine-rich 12 isoform a [Homo sapiens] Length = 624 Score = 53.1 bits (126), Expect = 3e-07 Identities = 36/170 (21%), Positives = 70/170 (41%), Gaps = 31/170 (18%) Query: 122 ETDSDQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITA 181 E +S + + G ++ +S + S K +K + K + RSH + + +K+ Sbjct: 294 EPESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDR----- 348 Query: 182 DSSSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEES 241 R+ K PHK++ KSR++ + + SHS D + E+ Sbjct: 349 ---------------RRSKSPHKKRSKSRERRKSR---------SRSHSRDKRKDTREKI 384 Query: 242 EERDTKKTKRKKREKKAHTSVANNEIQERTNKRTNWKVATDERSAESSED 291 +E++ + K K REK+ + +ER + K +R + +D Sbjct: 385 KEKE--RVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKD 432 Score = 52.0 bits (123), Expect = 6e-07 Identities = 35/149 (23%), Positives = 68/149 (45%), Gaps = 11/149 (7%) Query: 143 STHESRKHKKSKKSHKKKQKKRS-HKKQKKSKKEATDITADSSSEFSEETGASGTRKGKQ 201 S H SR H +S+ K +++ +S HKK+ KS++ + S + ++T K + Sbjct: 331 SKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERV 390 Query: 202 PHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEERDTKKTKRKKREKKAHTS 261 K ++K R++ ++ E E + D ++ E+D +K K K RE++ Sbjct: 391 KEKDREKEREREKER-----EKEKERGKNKDR-----DKEREKDREKDKEKDREREREKE 440 Query: 262 VANNEIQERTNKRTNWKVATDERSAESSE 290 + +E+ ++ K +RS E E Sbjct: 441 HEKDRDKEKEKEQDKEKEREKDRSKEIDE 469 Score = 49.7 bits (117), Expect = 3e-06 Identities = 42/163 (25%), Positives = 73/163 (44%), Gaps = 8/163 (4%) Query: 119 EEFETDSDQQDITNGKKTSPQVKSSTHE-SRKHKKSKKSHKKKQKKRSHKKQKKSKKEAT 177 +E E D D++ K + K + E K KK KKS + + ++ + S +E Sbjct: 439 KEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERR 498 Query: 178 DITADSSSEFSEETGASGTRKGKQ---PHKRKKKSRKKSLKKPALF--LEAESNTSHSDD 232 + SSS S T + RK + P R KK +K+ ++ + E E +TS Sbjct: 499 RRRSRSSSR-SPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKS 557 Query: 233 SASSSSEESEERDTKKTKRKKREKKAHTSVANNEIQERTNKRT 275 S +E E+++ K K+ K+ +SV + E+ ++ RT Sbjct: 558 SNDRDGKEKLEKNSTSLKEKEHNKEPDSSV-SKEVDDKDAPRT 599 Score = 45.4 bits (106), Expect = 6e-05 Identities = 36/180 (20%), Positives = 73/180 (40%), Gaps = 13/180 (7%) Query: 123 TDSDQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQK--------KSKK 174 + S + ++ + S Q +S K+SK ++K + RSH + K K K+ Sbjct: 329 SQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKE 388 Query: 175 EATDITADSSSEFSEETGASGTR-KGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDS 233 + + E +E R K K K ++K R+K +K + + D Sbjct: 389 RVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKE 448 Query: 234 ASSSSEESEERDTKKTK----RKKREKKAHTSVANNEIQERTNKRTNWKVATDERSAESS 289 ++ +ER+ ++K ++K++KK+ T + R+ + + RS+ S Sbjct: 449 KEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRS 508 Score = 44.7 bits (104), Expect = 1e-04 Identities = 55/269 (20%), Positives = 103/269 (38%), Gaps = 36/269 (13%) Query: 16 RHTDAHNKIQE-----ESDMWKIRELEKQMEDAYRGTKRKMLPSSSSRMRSDGFDEESQR 70 + D KI+E E D K RE EK+ E K K + R +++ +R Sbjct: 376 KRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDRER 435 Query: 71 YYWRPKNEISGTLEDDFLKAKSWNKKFYDYEANMPDRWGHSGYKELYPEEFETDSDQQDI 130 + E + D K K +K+ + DR KE+ E+ + D + Sbjct: 436 -----EREKEHEKDRDKEKEKEQDKE----KEREKDR-----SKEI-DEKRKKDKKSRTP 480 Query: 131 TNGKKTSPQVKSSTHESRKHK--------KSKKSHKKKQKKRSHKKQKKSKKEATDITAD 182 S + +SS+ E R+ + ++ K+ K+K + + + K + + D Sbjct: 481 PRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERD 540 Query: 183 SSSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESE 242 SE E ++ RK K+K K S + H+ + SS S+E + Sbjct: 541 HISERRERERSTSMRKSSNDRDGKEKLEKNS--------TSLKEKEHNKEPDSSVSKEVD 592 Query: 243 ERDTKKTKRKKREKKAHTSVANNEIQERT 271 ++D +T+ K + + + + +T Sbjct: 593 DKDAPRTEENKIQHNGNCQLNEENLSTKT 621 Score = 42.4 bits (98), Expect = 5e-04 Identities = 34/181 (18%), Positives = 76/181 (41%), Gaps = 9/181 (4%) Query: 119 EEFETDSDQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATD 178 +E E + ++ + K + + E + ++ +K H+K + K K+Q K K+ D Sbjct: 403 KEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKD 462 Query: 179 ITADSSSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSS 238 + + + ++ + + +R + S ++ ++ + TS + SS S Sbjct: 463 RSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRS 522 Query: 239 EESEERDTKKTKRKK--------REKKAHTSVANNEIQERTNKRTNWKVATDERSAESSE 290 R+ K KR+K RE++ TS+ + +R K K +T + E ++ Sbjct: 523 PSPRSRNKKDKKREKERDHISERRERERSTSMRKSS-NDRDGKEKLEKNSTSLKEKEHNK 581 Query: 291 D 291 + Sbjct: 582 E 582 Score = 37.0 bits (84), Expect = 0.021 Identities = 31/187 (16%), Positives = 69/187 (36%), Gaps = 32/187 (17%) Query: 105 PDRWGHSGYKELYPEEFETDSDQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKR 164 P + HS + P E + +++ K + +S + + + K + +K + R Sbjct: 250 PLKINHSNNAIVKPPEMTPQAAAKELEEVMKRVREAQSFISAAIEPESGKSNERKGGRSR 309 Query: 165 SHKKQKKSKKEATDITADSSSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAE 224 SH + K +R + H R+K+S+ K + Sbjct: 310 SHTRSK-------------------------SRSSSKSHSRRKRSQSKHRSR-------S 337 Query: 225 SNTSHSDDSASSSSEESEERDTKKTKRKKREKKAHTSVANNEIQERTNKRTNWKVATDER 284 N S S S+ ++ +K +R+K ++H+ + +E+ ++ K E+ Sbjct: 338 HNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREK 397 Query: 285 SAESSED 291 E ++ Sbjct: 398 EREREKE 404 >gi|104526627 triadin [Homo sapiens] Length = 729 Score = 53.1 bits (126), Expect = 3e-07 Identities = 37/155 (23%), Positives = 68/155 (43%), Gaps = 25/155 (16%) Query: 119 EEFETDSDQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATD 178 E+ E D +D G+ P ++ K +K +K +K Q K +HK+++K K++ + Sbjct: 117 EDEEDDDGDEDTDKGEIDEPPLRKKEIHKDKTEKQEKPERKIQTKVTHKEKEKGKEKVRE 176 Query: 179 ITADSSSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSS 238 K K K K + + +KP E+ T + + ++ Sbjct: 177 -------------------KEKPEKKATHKEKIEKKEKP------ETKTLAKEQKKAKTA 211 Query: 239 EESEERDTKKTKRKKREKKAHTSVANNEIQERTNK 273 E+SEE+ K+ K K+EK T+ E+Q+ +K Sbjct: 212 EKSEEKTKKEVKGGKQEKVKQTAAKVKEVQKTPSK 246 Score = 43.5 bits (101), Expect = 2e-04 Identities = 59/266 (22%), Positives = 105/266 (39%), Gaps = 25/266 (9%) Query: 37 EKQMEDAYRGTKRKMLPSSSSRMRSDGFDEESQRYYWRPKNEISGTLEDDFLKAKSWNKK 96 E++ + +G K++ + ++++++ E Q+ +PK + ++ +K K Sbjct: 215 EEKTKKEVKGGKQEKVKQTAAKVK------EVQKTPSKPKEKED---KEKAAVSKHEQKD 265 Query: 97 FYDYEANMPDRWGHSGYKELYPEEFETDSDQQDITNGKKTSPQVKSSTHESRKHKKSKKS 156 Y + M D + H K + + SP ++ E +K +K S Sbjct: 266 QYAFCRYMIDIFVHGDLKPGQSPAIPPPLPTEQASRPTPASPALEEKEGEKKKAEKKVTS 325 Query: 157 HKKKQKKRSHKKQKKSKKEATDITADSSSEFSEETGASGTRKGKQPHKRKKKSRK---KS 213 KK++K KK K K+ A D+ + SE GT K KK +K K Sbjct: 326 ETKKKEKEDIKK-KSEKETAIDVEKKEPGKASETK--QGTVKIAAQAAAKKDEKKEDSKK 382 Query: 214 LKKPALF-----LEAESNTSHSDDSASSSSEESEERDTK---KTKRKKREKKAHT--SVA 263 KKPA + E H + + S E S D + KT+R K E A + Sbjct: 383 TKKPAEVEQPKGKKQEKKEKHVEPAKSPKKEHSVPSDKQVKAKTERAKEEIGAVSIKKAV 442 Query: 264 NNEIQERTNKRTNWKVATDERSAESS 289 + +E+T K ++ ++ SS Sbjct: 443 PGKKEEKTTKTVEQEIRKEKSGKTSS 468 Score = 39.3 bits (90), Expect = 0.004 Identities = 29/130 (22%), Positives = 57/130 (43%), Gaps = 12/130 (9%) Query: 122 ETDSDQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKK--QKKSKKEATDI 179 E D+ + + Q K + E K K+ + +K +KK +HK+ +KK K E + Sbjct: 142 EIHKDKTEKQEKPERKIQTKVTHKEKEKGKEKVREKEKPEKKATHKEKIEKKEKPETKTL 201 Query: 180 TAD----SSSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSAS 235 + ++E SEE + GKQ ++ ++ K ++K S +D Sbjct: 202 AKEQKKAKTAEKSEEKTKKEVKGGKQEKVKQTAAKVKEVQK------TPSKPKEKEDKEK 255 Query: 236 SSSEESEERD 245 ++ + E++D Sbjct: 256 AAVSKHEQKD 265 Score = 34.7 bits (78), Expect = 0.10 Identities = 65/294 (22%), Positives = 110/294 (37%), Gaps = 47/294 (15%) Query: 32 KIRELEKQMEDAYRGTKRKMLPSSSS-RMRSDGFDEE------SQRYYWRPKNEISGTLE 84 K + EK +E A K +PS + +++ EE + + + + + T+E Sbjct: 396 KQEKKEKHVEPAKSPKKEHSVPSDKQVKAKTERAKEEIGAVSIKKAVPGKKEEKTTKTVE 455 Query: 85 DDFLKAKSWNKKFYDYEANMPDRWGHSGYKELYP-----EEFETDSDQQDITNGK----- 134 + K KS + + D+ G +E P +E ET D++ GK Sbjct: 456 QEIRKEKSGKTS-----SILKDKEPIKGKEEKVPASLKEKEPETKKDEKMSKAGKEVKPK 510 Query: 135 ----------KTSPQVKSSTHE--SRKHKKSKKSHKKKQKKRSH-KKQKKSKKEATDITA 181 K PQ+K S K + K+ K +K SH K ++K K+ +T Sbjct: 511 PPQLQGKKEEKPEPQIKKEAKPAISEKVQIHKQDIVKPEKTVSHGKPEEKVLKQVKAVTI 570 Query: 182 DSSSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEES 241 E+T K + +R+ S K KP +E S + S E Sbjct: 571 -------EKTAKPKPTKKAEHREREPPSIKTDKPKPTPKGTSEVTESGKKKTEISEKESK 623 Query: 242 EERDTKKTKRKK----REKKAHTSVANNEIQERTNKRTNWKVATDERSAESSED 291 E+ D K + +K +E +V E R +K V +++ E +ED Sbjct: 624 EKADMKHLREEKVSTRKESLQLHNVTKAEKPARVSKDVE-DVPASKKAKEGTED 676 Score = 31.6 bits (70), Expect = 0.86 Identities = 39/185 (21%), Positives = 78/185 (42%), Gaps = 20/185 (10%) Query: 114 KELYPEEFETDSDQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSK 173 K+ E+ + S+++ + +K P S T + ++ + KK +KK + SK Sbjct: 328 KKKEKEDIKKKSEKETAIDVEKKEPGKASETKQGTVKIAAQAAAKKDEKK------EDSK 381 Query: 174 KEATDITADSSSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPA-LFLEAESNTSHSDD 232 K +E + G +K K H KS KK P+ ++A++ + + Sbjct: 382 K------TKKPAEVEQPKGKKQEKKEK--HVEPAKSPKKEHSVPSDKQVKAKTERAKEEI 433 Query: 233 SASSSSE----ESEERDTKKTKRK-KREKKAHTSVANNEIQERTNKRTNWKVATDERSAE 287 A S + + EE+ TK +++ ++EK TS + + K + E+ E Sbjct: 434 GAVSIKKAVPGKKEEKTTKTVEQEIRKEKSGKTSSILKDKEPIKGKEEKVPASLKEKEPE 493 Query: 288 SSEDD 292 + +D+ Sbjct: 494 TKKDE 498 >gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [Homo sapiens] Length = 508 Score = 53.1 bits (126), Expect = 3e-07 Identities = 36/170 (21%), Positives = 70/170 (41%), Gaps = 31/170 (18%) Query: 122 ETDSDQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITA 181 E +S + + G ++ +S + S K +K + K + RSH + + +K+ Sbjct: 178 EPESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRSRQKDR----- 232 Query: 182 DSSSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEES 241 R+ K PHK++ KSR++ + + SHS D + E+ Sbjct: 233 ---------------RRSKSPHKKRSKSRERRKSR---------SRSHSRDKRKDTREKI 268 Query: 242 EERDTKKTKRKKREKKAHTSVANNEIQERTNKRTNWKVATDERSAESSED 291 +E++ + K K REK+ + +ER + K +R + +D Sbjct: 269 KEKE--RVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKD 316 Score = 52.0 bits (123), Expect = 6e-07 Identities = 35/149 (23%), Positives = 68/149 (45%), Gaps = 11/149 (7%) Query: 143 STHESRKHKKSKKSHKKKQKKRS-HKKQKKSKKEATDITADSSSEFSEETGASGTRKGKQ 201 S H SR H +S+ K +++ +S HKK+ KS++ + S + ++T K + Sbjct: 215 SKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERV 274 Query: 202 PHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEERDTKKTKRKKREKKAHTS 261 K ++K R++ ++ E E + D ++ E+D +K K K RE++ Sbjct: 275 KEKDREKEREREKER-----EKEKERGKNKDR-----DKEREKDREKDKEKDREREREKE 324 Query: 262 VANNEIQERTNKRTNWKVATDERSAESSE 290 + +E+ ++ K +RS E E Sbjct: 325 HEKDRDKEKEKEQDKEKEREKDRSKEIDE 353 Score = 49.7 bits (117), Expect = 3e-06 Identities = 42/163 (25%), Positives = 73/163 (44%), Gaps = 8/163 (4%) Query: 119 EEFETDSDQQDITNGKKTSPQVKSSTHE-SRKHKKSKKSHKKKQKKRSHKKQKKSKKEAT 177 +E E D D++ K + K + E K KK KKS + + ++ + S +E Sbjct: 323 KEHEKDRDKEKEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERR 382 Query: 178 DITADSSSEFSEETGASGTRKGKQ---PHKRKKKSRKKSLKKPALF--LEAESNTSHSDD 232 + SSS S T + RK + P R KK +K+ ++ + E E +TS Sbjct: 383 RRRSRSSSR-SPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKS 441 Query: 233 SASSSSEESEERDTKKTKRKKREKKAHTSVANNEIQERTNKRT 275 S +E E+++ K K+ K+ +SV + E+ ++ RT Sbjct: 442 SNDRDGKEKLEKNSTSLKEKEHNKEPDSSV-SKEVDDKDAPRT 483 Score = 45.4 bits (106), Expect = 6e-05 Identities = 36/180 (20%), Positives = 73/180 (40%), Gaps = 13/180 (7%) Query: 123 TDSDQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQK--------KSKK 174 + S + ++ + S Q +S K+SK ++K + RSH + K K K+ Sbjct: 213 SQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKE 272 Query: 175 EATDITADSSSEFSEETGASGTR-KGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDS 233 + + E +E R K K K ++K R+K +K + + D Sbjct: 273 RVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKE 332 Query: 234 ASSSSEESEERDTKKTK----RKKREKKAHTSVANNEIQERTNKRTNWKVATDERSAESS 289 ++ +ER+ ++K ++K++KK+ T + R+ + + RS+ S Sbjct: 333 KEKEQDKEKEREKDRSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRS 392 Score = 44.7 bits (104), Expect = 1e-04 Identities = 55/269 (20%), Positives = 103/269 (38%), Gaps = 36/269 (13%) Query: 16 RHTDAHNKIQE-----ESDMWKIRELEKQMEDAYRGTKRKMLPSSSSRMRSDGFDEESQR 70 + D KI+E E D K RE EK+ E K K + R +++ +R Sbjct: 260 KRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDRER 319 Query: 71 YYWRPKNEISGTLEDDFLKAKSWNKKFYDYEANMPDRWGHSGYKELYPEEFETDSDQQDI 130 + E + D K K +K+ + DR KE+ E+ + D + Sbjct: 320 -----EREKEHEKDRDKEKEKEQDKE----KEREKDR-----SKEI-DEKRKKDKKSRTP 364 Query: 131 TNGKKTSPQVKSSTHESRKHK--------KSKKSHKKKQKKRSHKKQKKSKKEATDITAD 182 S + +SS+ E R+ + ++ K+ K+K + + + K + + D Sbjct: 365 PRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERD 424 Query: 183 SSSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESE 242 SE E ++ RK K+K K S + H+ + SS S+E + Sbjct: 425 HISERRERERSTSMRKSSNDRDGKEKLEKNS--------TSLKEKEHNKEPDSSVSKEVD 476 Query: 243 ERDTKKTKRKKREKKAHTSVANNEIQERT 271 ++D +T+ K + + + + +T Sbjct: 477 DKDAPRTEENKIQHNGNCQLNEENLSTKT 505 Score = 42.4 bits (98), Expect = 5e-04 Identities = 34/181 (18%), Positives = 76/181 (41%), Gaps = 9/181 (4%) Query: 119 EEFETDSDQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATD 178 +E E + ++ + K + + E + ++ +K H+K + K K+Q K K+ D Sbjct: 287 KEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKD 346 Query: 179 ITADSSSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSS 238 + + + ++ + + +R + S ++ ++ + TS + SS S Sbjct: 347 RSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRS 406 Query: 239 EESEERDTKKTKRKK--------REKKAHTSVANNEIQERTNKRTNWKVATDERSAESSE 290 R+ K KR+K RE++ TS+ + +R K K +T + E ++ Sbjct: 407 PSPRSRNKKDKKREKERDHISERRERERSTSMRKSS-NDRDGKEKLEKNSTSLKEKEHNK 465 Query: 291 D 291 + Sbjct: 466 E 466 Score = 37.0 bits (84), Expect = 0.021 Identities = 31/187 (16%), Positives = 69/187 (36%), Gaps = 32/187 (17%) Query: 105 PDRWGHSGYKELYPEEFETDSDQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKR 164 P + HS + P E + +++ K + +S + + + K + +K + R Sbjct: 134 PLKINHSNNAIVKPPEMTPQAAAKELEEVMKRVREAQSFISAAIEPESGKSNERKGGRSR 193 Query: 165 SHKKQKKSKKEATDITADSSSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAE 224 SH + K +R + H R+K+S+ K + Sbjct: 194 SHTRSK-------------------------SRSSSKSHSRRKRSQSKHRSR-------S 221 Query: 225 SNTSHSDDSASSSSEESEERDTKKTKRKKREKKAHTSVANNEIQERTNKRTNWKVATDER 284 N S S S+ ++ +K +R+K ++H+ + +E+ ++ K E+ Sbjct: 222 HNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREK 281 Query: 285 SAESSED 291 E ++ Sbjct: 282 EREREKE 288 >gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sapiens] Length = 570 Score = 52.4 bits (124), Expect = 5e-07 Identities = 43/251 (17%), Positives = 109/251 (43%), Gaps = 21/251 (8%) Query: 25 QEESDMW----KIRELEKQMEDAYRGTKRKMLPSSSSRMRSDGFDEESQRYYWRPKNEIS 80 ++E MW KIRELE++M + + +++ ++R +E + WR + +I Sbjct: 334 RQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKI- 392 Query: 81 GTLEDDFLKAKSWNKKFYDYEANMPDRWGHSGYKELYPEEFETDSDQQDITNGKKTSPQV 140 + +K + E M ++ G +E E E + +Q+ +K Q Sbjct: 393 ----------REQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQE----EKMRRQE 438 Query: 141 KSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITADSSSEFSEETGASGTRKGK 200 + + +K ++ ++ +++++ +++K ++E ++ + EE K + Sbjct: 439 EKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIR 498 Query: 201 QPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEERDTK--KTKRKKREKKA 258 + K+ ++ +K ++ + E E ++ E+ +E++ K + + K RE++ Sbjct: 499 EQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMREQEV 558 Query: 259 HTSVANNEIQE 269 ++QE Sbjct: 559 RLRQQEEKMQE 569 >gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens] Length = 2454 Score = 52.0 bits (123), Expect = 6e-07 Identities = 71/309 (22%), Positives = 124/309 (40%), Gaps = 48/309 (15%) Query: 18 TDAHNKIQEESDMWKIRELEKQMEDAYRGTKRKMLPSSSSRMRSDGFDEESQRYYWRPKN 77 TD +K+ + + E+ K E K K L + + + DG + ++++ K+ Sbjct: 880 TDGVDKLSGKEQSFTSLEVRKVAETK---EKSKHLKTKTCKKVQDGLSDIAEKFL--KKD 934 Query: 78 EISGTLEDDFLKAKSWN---KKFYDYEAN---MPDRW-GHSGYKELYPEEFETDSDQQDI 130 + T EDD ++K KK D++ M ++ S E PE E + I Sbjct: 935 QSDETSEDDKKQSKKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLPEREEICHFPKGI 994 Query: 131 -------TNGKKTSPQVKSSTH--------------------ESRKHKKSKKSHKKKQKK 163 T+G+K S +++ T +S + KKSK ++KK Sbjct: 995 KQIKNGTTDGEKKSKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSEDKKSKNGAYGREKK 1054 Query: 164 RSHKKQKKSKKEATDITADSSSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEA 223 R K S+K ++D+ +E G + + K KR + +++L E Sbjct: 1055 RCKLLGKSSRKRQDCSSSDTEKYSMKEDGCNSSDKRL---KRIELRERRNLSSKRNTKEI 1111 Query: 224 ESNTSHSDDSASSSSEESEERDTKKTKRKKREKKAHTSVANNEIQERTNKRTNWKVATDE 283 +S +S SD +EES E + KK +R +KKA RT+ + T Sbjct: 1112 QSGSSSSD------AEESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADITSS 1165 Query: 284 RSAESSEDD 292 S++ +DD Sbjct: 1166 SSSDIEDDD 1174 Score = 42.7 bits (99), Expect = 4e-04 Identities = 48/196 (24%), Positives = 75/196 (38%), Gaps = 33/196 (16%) Query: 122 ETDSDQQDITNGKKTSPQVKS----STHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEAT 177 E+DSD ++ + ++ S ES + KK+K K+ K R+ +K E + Sbjct: 1285 ESDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDS 1344 Query: 178 DITADSSSEF---SEETGASGTRKGKQP--------HKRKKKSRK-------KSLKKPAL 219 D SE SE+ TR K+ +K+KKK R+ S K Sbjct: 1345 DFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNS 1404 Query: 220 FLEAESNTSHSDDSASSSSEESEERDTKKTKRKKREK--------KAHTSVANNEIQERT 271 E E ++ EE +E D K+ K R+K K T N +E Sbjct: 1405 EEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKGRKKIRKILKDDKLRTETQNALKEEEE 1464 Query: 272 NKRTNWKVATDERSAE 287 ++ ++A ER E Sbjct: 1465 RRK---RIAERERERE 1477 Score = 42.0 bits (97), Expect = 6e-04 Identities = 40/174 (22%), Positives = 79/174 (45%), Gaps = 18/174 (10%) Query: 123 TDSDQQDITNGKKTSPQVKSSTHESRKHKKSKKS---------HKKKQKKRS--HKKQKK 171 +D+D +I KT +K+ + K K+ +KS K K K S KK+++ Sbjct: 712 SDTDINEIHTNHKTLYDLKTQAGKDDKGKRKRKSSTSGSDFDTKKGKSAKSSIISKKKRQ 771 Query: 172 SKKEATDITADSSSEFS--EETGASGTRKGKQPH-KRKKKSRKKSLKKPALFLEAESNTS 228 ++ E+++ ++ E + GA+ T K + P+ K S + K + + N Sbjct: 772 TQSESSNYDSELEKEIKSMSKIGAARTTKKRIPNTKDFDSSEDEKHSKKGMDNQGHKNLK 831 Query: 229 HSDDSASSSSEESEERDTKKTKRKKREKKAHTSVANNEIQERTNKRTNWKVATD 282 S + +S +E +ER+T + +K T++ E+++R K+ +TD Sbjct: 832 TSQEGSSDDAERKQERETFSSAEGTVDK--DTTIM--ELRDRLPKKQQASASTD 881 Score = 41.6 bits (96), Expect = 8e-04 Identities = 50/227 (22%), Positives = 86/227 (37%), Gaps = 26/227 (11%) Query: 19 DAHNKIQEESDMWKIRELEKQMEDAYRGTKRKMLPSSSSRMRSDGFDEESQRYYWRPKNE 78 +A N++ ESD E K+ +R + K+ S DG E ++ + E Sbjct: 1277 EAKNQVNSESD--SDSEESKKPRYRHRLLRHKLTVS-------DGESGEEKKTKPKEHKE 1327 Query: 79 ISGTLEDDFLKAKSWNKKFYDYEANMPDRWGHSGYKELYPEEFETDSDQQDITNGKKTSP 138 + G N++ E + + SG E E E++ +Q+ T K + Sbjct: 1328 VKGR-----------NRRKVSSEDSEDSDFQESGVSE---EVSESEDEQRPRTRSAKKAE 1373 Query: 139 QVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITADSSSEFSEETGASGTRK 198 ++ S K KK ++ K ++ S K ++E + E EE Sbjct: 1374 LEENQ--RSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDD 1431 Query: 199 GKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEERD 245 K P K +KK R K LK L E ++ ++ +E ER+ Sbjct: 1432 SKSPGKGRKKIR-KILKDDKLRTETQNALKEEEERRKRIAERERERE 1477 Score = 39.7 bits (91), Expect = 0.003 Identities = 35/165 (21%), Positives = 70/165 (42%), Gaps = 14/165 (8%) Query: 133 GKKTSPQVKSSTHESRKH--KKSKKSHKKKQKKRSHKKQKK---SKKEATDITADSSSEF 187 GK + + S+ ++ K+ K+ + K+ KR ++++ SK+ +I + SSS Sbjct: 1060 GKSSRKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNLSSKRNTKEIQSGSSSSD 1119 Query: 188 SEETGASGTRKGKQPHKRKK---------KSRKKSLKKPALFLEAESNTSHSDDSASSSS 238 +EE+ +K ++ +KK S + S K+ + + S++ DD +S Sbjct: 1120 AEESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADITSSSSSDIEDDDQNSIG 1179 Query: 239 EESEERDTKKTKRKKREKKAHTSVANNEIQERTNKRTNWKVATDE 283 E S + K + +HT + E +K V D+ Sbjct: 1180 EGSSDEQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDDDD 1224 Score = 39.3 bits (90), Expect = 0.004 Identities = 62/308 (20%), Positives = 116/308 (37%), Gaps = 42/308 (13%) Query: 26 EESDMWKIRELEKQMEDAYRGTKRKMLPSSSSRMRSDGFDEESQRYYWRPKNEIS-GTLE 84 E++ K R K+ + KR L +S+ R ++D S +N I G+ + Sbjct: 1125 EDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADITSSSSSDIEDDDQNSIGEGSSD 1184 Query: 85 DDFLKAKSWNKKFYDYEANMPDRWGHSGYKELYPEEFETDSDQQDITNG---KKTSPQVK 141 + +K + N + G + P + D D D N K ++K Sbjct: 1185 EQKIKPVTENLVLSSHTGFCQSS-GDEALSKSVPVTVDDDDDDNDPENRIAKKMLLEEIK 1243 Query: 142 ---SSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITADSSSEFSEET------- 191 SS + + ++ K+ K+ + K + +DS SE S++ Sbjct: 1244 ANLSSDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSESDSDSEESKKPRYRHRLL 1303 Query: 192 --------GASGTRKGKQPHKRKK---KSRKKSLKKPAL---FLEA--ESNTSHSDD--- 232 G SG K +P + K+ ++R+K + + F E+ S S+D Sbjct: 1304 RHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQR 1363 Query: 233 ----SASSSSEESEERDTKKTKRKKR----EKKAHTSVANNEIQERTNKRTNWKVATDER 284 SA + E +R K+ K+++R E + + +N+E +E + + +E Sbjct: 1364 PRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEE 1423 Query: 285 SAESSEDD 292 E DD Sbjct: 1424 EEEDENDD 1431 Score = 38.9 bits (89), Expect = 0.005 Identities = 47/189 (24%), Positives = 78/189 (41%), Gaps = 37/189 (19%) Query: 119 EEFETDSDQQDITNGKK---TSPQVK--SSTHESRKHKKSKKSHKKKQKKRSHKKQKKSK 173 ++ +D D +GK+ TS +V+ + T E KH K+K KK Q S +K K Sbjct: 874 QQASASTDGVDKLSGKEQSFTSLEVRKVAETKEKSKHLKTKTC-KKVQDGLSDIAEKFLK 932 Query: 174 KEATDITADSSSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDS 233 K+ +D T++ + S++ GT + K+P KKK ++ E S D Sbjct: 933 KDQSDETSEDDKKQSKK----GTEEKKKPSDFKKK-----------VIKMEQQYESSSDG 977 Query: 234 ASSSSEESE-----------ERDTKKTKRKKREKKAHTSVANNEIQERTNKRTNWKVATD 282 E E + T ++K ++ + TS +E+ + K T Sbjct: 978 TEKLPEREEICHFPKGIKQIKNGTTDGEKKSKKIRDKTSKKKDELSDYAEKSTG-----K 1032 Query: 283 ERSAESSED 291 S +SSED Sbjct: 1033 GDSCDSSED 1041 Score = 35.4 bits (80), Expect = 0.060 Identities = 42/199 (21%), Positives = 82/199 (41%), Gaps = 30/199 (15%) Query: 110 HSGYKELYPEEFETDSDQQDITNGKKTSPQVKSSTHESRKHKKSKKS--HKKKQKKRSHK 167 H+ +K LY + +T + + D K+ S S +++K K +K S KKK++ +S Sbjct: 720 HTNHKTLY--DLKTQAGKDDKGKRKRKS-STSGSDFDTKKGKSAKSSIISKKKRQTQSES 776 Query: 168 KQKKSKKE-------------ATDITADSSSEFSEETGASGTRKG--KQPHKRKKKSRKK 212 S+ E T ++ +F ++KG Q HK K S++ Sbjct: 777 SNYDSELEKEIKSMSKIGAARTTKKRIPNTKDFDSSEDEKHSKKGMDNQGHKNLKTSQEG 836 Query: 213 SLKKPALFLEAESNTSHSDDSASSSSEESEERDTKKTK-RKKREKKAHTSVANNEIQERT 271 S ++ + SS+E + ++DT + R + KK S + + + + + Sbjct: 837 S---------SDDAERKQERETFSSAEGTVDKDTTIMELRDRLPKKQQASASTDGVDKLS 887 Query: 272 NKRTNWKVATDERSAESSE 290 K ++ + AE+ E Sbjct: 888 GKEQSFTSLEVRKVAETKE 906 Score = 28.9 bits (63), Expect = 5.6 Identities = 31/168 (18%), Positives = 61/168 (36%), Gaps = 16/168 (9%) Query: 12 RNVIRHTDAHNKIQEESDMWKIRELEKQMEDAYRGTKRKMLPSSSSRMRSDGFDEESQRY 71 R V + QE ++ E E + R K+ L EE+QR Sbjct: 1334 RKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAEL-------------EENQRS 1380 Query: 72 YWRPKNEISGTLEDDFLKAKSWNKKFYDYEANMPDRWGHSGYKELYPEEFETDSDQQDIT 131 Y + K +++D + S NK + E + +E EE E D + Sbjct: 1381 YKQKKKRRRIKVQED---SSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGK 1437 Query: 132 NGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDI 179 KK +K + K+ +++++ +++++ +E +I Sbjct: 1438 GRKKIRKILKDDKLRTETQNALKEEEERRKRIAEREREREKLREVIEI 1485 Score = 28.5 bits (62), Expect = 7.3 Identities = 16/64 (25%), Positives = 33/64 (51%), Gaps = 7/64 (10%) Query: 229 HSDDSASSSSEESEERDTKKTKRKKREKKAHTSVANNEIQERTNKRTNWKVATDERSAES 288 +S + +SSSE+S+ + ++KRK S+ ++ K + + ++ S E+ Sbjct: 59 NSKEEGTSSSEKSKSSGSSRSKRK-------PSIVTKYVESDDEKPLDDETVNEDASNEN 111 Query: 289 SEDD 292 SE+D Sbjct: 112 SEND 115 Score = 28.1 bits (61), Expect = 9.5 Identities = 29/150 (19%), Positives = 64/150 (42%), Gaps = 12/150 (8%) Query: 119 EEFETDSDQQDITNGK--------KTSPQVKSSTHESRKHKKSKKSHKKKQKKRS---HK 167 ++F++ D++ G KTS + S E ++ +++ S + K + Sbjct: 807 KDFDSSEDEKHSKKGMDNQGHKNLKTSQEGSSDDAERKQERETFSSAEGTVDKDTTIMEL 866 Query: 168 KQKKSKKEATDITADSSSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNT 227 + + KK+ + D + S + + + + ++ + K+KS+ K + S+ Sbjct: 867 RDRLPKKQQASASTDGVDKLSGKEQSFTSLEVRKVAETKEKSKHLKTKTCKKVQDGLSDI 926 Query: 228 SHSDDSASSSSEESEERDTKKTKRKKREKK 257 + S E SE+ D K++K+ EKK Sbjct: 927 AEKFLKKDQSDETSED-DKKQSKKGTEEKK 955 >gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens] Length = 2492 Score = 52.0 bits (123), Expect = 6e-07 Identities = 71/309 (22%), Positives = 124/309 (40%), Gaps = 48/309 (15%) Query: 18 TDAHNKIQEESDMWKIRELEKQMEDAYRGTKRKMLPSSSSRMRSDGFDEESQRYYWRPKN 77 TD +K+ + + E+ K E K K L + + + DG + ++++ K+ Sbjct: 918 TDGVDKLSGKEQSFTSLEVRKVAETK---EKSKHLKTKTCKKVQDGLSDIAEKFL--KKD 972 Query: 78 EISGTLEDDFLKAKSWN---KKFYDYEAN---MPDRW-GHSGYKELYPEEFETDSDQQDI 130 + T EDD ++K KK D++ M ++ S E PE E + I Sbjct: 973 QSDETSEDDKKQSKKGTEEKKKPSDFKKKVIKMEQQYESSSDGTEKLPEREEICHFPKGI 1032 Query: 131 -------TNGKKTSPQVKSSTH--------------------ESRKHKKSKKSHKKKQKK 163 T+G+K S +++ T +S + KKSK ++KK Sbjct: 1033 KQIKNGTTDGEKKSKKIRDKTSKKKDELSDYAEKSTGKGDSCDSSEDKKSKNGAYGREKK 1092 Query: 164 RSHKKQKKSKKEATDITADSSSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEA 223 R K S+K ++D+ +E G + + K KR + +++L E Sbjct: 1093 RCKLLGKSSRKRQDCSSSDTEKYSMKEDGCNSSDKRL---KRIELRERRNLSSKRNTKEI 1149 Query: 224 ESNTSHSDDSASSSSEESEERDTKKTKRKKREKKAHTSVANNEIQERTNKRTNWKVATDE 283 +S +S SD +EES E + KK +R +KKA RT+ + T Sbjct: 1150 QSGSSSSD------AEESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADITSS 1203 Query: 284 RSAESSEDD 292 S++ +DD Sbjct: 1204 SSSDIEDDD 1212 Score = 42.7 bits (99), Expect = 4e-04 Identities = 48/196 (24%), Positives = 75/196 (38%), Gaps = 33/196 (16%) Query: 122 ETDSDQQDITNGKKTSPQVKS----STHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEAT 177 E+DSD ++ + ++ S ES + KK+K K+ K R+ +K E + Sbjct: 1323 ESDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDS 1382 Query: 178 DITADSSSEF---SEETGASGTRKGKQP--------HKRKKKSRK-------KSLKKPAL 219 D SE SE+ TR K+ +K+KKK R+ S K Sbjct: 1383 DFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNS 1442 Query: 220 FLEAESNTSHSDDSASSSSEESEERDTKKTKRKKREK--------KAHTSVANNEIQERT 271 E E ++ EE +E D K+ K R+K K T N +E Sbjct: 1443 EEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKGRKKIRKILKDDKLRTETQNALKEEEE 1502 Query: 272 NKRTNWKVATDERSAE 287 ++ ++A ER E Sbjct: 1503 RRK---RIAERERERE 1515 Score = 42.0 bits (97), Expect = 6e-04 Identities = 40/174 (22%), Positives = 79/174 (45%), Gaps = 18/174 (10%) Query: 123 TDSDQQDITNGKKTSPQVKSSTHESRKHKKSKKS---------HKKKQKKRS--HKKQKK 171 +D+D +I KT +K+ + K K+ +KS K K K S KK+++ Sbjct: 750 SDTDINEIHTNHKTLYDLKTQAGKDDKGKRKRKSSTSGSDFDTKKGKSAKSSIISKKKRQ 809 Query: 172 SKKEATDITADSSSEFS--EETGASGTRKGKQPH-KRKKKSRKKSLKKPALFLEAESNTS 228 ++ E+++ ++ E + GA+ T K + P+ K S + K + + N Sbjct: 810 TQSESSNYDSELEKEIKSMSKIGAARTTKKRIPNTKDFDSSEDEKHSKKGMDNQGHKNLK 869 Query: 229 HSDDSASSSSEESEERDTKKTKRKKREKKAHTSVANNEIQERTNKRTNWKVATD 282 S + +S +E +ER+T + +K T++ E+++R K+ +TD Sbjct: 870 TSQEGSSDDAERKQERETFSSAEGTVDK--DTTIM--ELRDRLPKKQQASASTD 919 Score = 41.6 bits (96), Expect = 8e-04 Identities = 50/227 (22%), Positives = 86/227 (37%), Gaps = 26/227 (11%) Query: 19 DAHNKIQEESDMWKIRELEKQMEDAYRGTKRKMLPSSSSRMRSDGFDEESQRYYWRPKNE 78 +A N++ ESD E K+ +R + K+ S DG E ++ + E Sbjct: 1315 EAKNQVNSESD--SDSEESKKPRYRHRLLRHKLTVS-------DGESGEEKKTKPKEHKE 1365 Query: 79 ISGTLEDDFLKAKSWNKKFYDYEANMPDRWGHSGYKELYPEEFETDSDQQDITNGKKTSP 138 + G N++ E + + SG E E E++ +Q+ T K + Sbjct: 1366 VKGR-----------NRRKVSSEDSEDSDFQESGVSE---EVSESEDEQRPRTRSAKKAE 1411 Query: 139 QVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITADSSSEFSEETGASGTRK 198 ++ S K KK ++ K ++ S K ++E + E EE Sbjct: 1412 LEENQ--RSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDD 1469 Query: 199 GKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEERD 245 K P K +KK R K LK L E ++ ++ +E ER+ Sbjct: 1470 SKSPGKGRKKIR-KILKDDKLRTETQNALKEEEERRKRIAERERERE 1515 Score = 39.7 bits (91), Expect = 0.003 Identities = 35/165 (21%), Positives = 70/165 (42%), Gaps = 14/165 (8%) Query: 133 GKKTSPQVKSSTHESRKH--KKSKKSHKKKQKKRSHKKQKK---SKKEATDITADSSSEF 187 GK + + S+ ++ K+ K+ + K+ KR ++++ SK+ +I + SSS Sbjct: 1098 GKSSRKRQDCSSSDTEKYSMKEDGCNSSDKRLKRIELRERRNLSSKRNTKEIQSGSSSSD 1157 Query: 188 SEETGASGTRKGKQPHKRKK---------KSRKKSLKKPALFLEAESNTSHSDDSASSSS 238 +EE+ +K ++ +KK S + S K+ + + S++ DD +S Sbjct: 1158 AEESSEDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADITSSSSSDIEDDDQNSIG 1217 Query: 239 EESEERDTKKTKRKKREKKAHTSVANNEIQERTNKRTNWKVATDE 283 E S + K + +HT + E +K V D+ Sbjct: 1218 EGSSDEQKIKPVTENLVLSSHTGFCQSSGDEALSKSVPVTVDDDD 1262 Score = 39.3 bits (90), Expect = 0.004 Identities = 62/308 (20%), Positives = 116/308 (37%), Gaps = 42/308 (13%) Query: 26 EESDMWKIRELEKQMEDAYRGTKRKMLPSSSSRMRSDGFDEESQRYYWRPKNEIS-GTLE 84 E++ K R K+ + KR L +S+ R ++D S +N I G+ + Sbjct: 1163 EDNKKKKQRTSSKKKAVIVKEKKRNSLRTSTKRKQADITSSSSSDIEDDDQNSIGEGSSD 1222 Query: 85 DDFLKAKSWNKKFYDYEANMPDRWGHSGYKELYPEEFETDSDQQDITNG---KKTSPQVK 141 + +K + N + G + P + D D D N K ++K Sbjct: 1223 EQKIKPVTENLVLSSHTGFCQSS-GDEALSKSVPVTVDDDDDDNDPENRIAKKMLLEEIK 1281 Query: 142 ---SSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITADSSSEFSEET------- 191 SS + + ++ K+ K+ + K + +DS SE S++ Sbjct: 1282 ANLSSDEDGSSDDEPEEGKKRTGKQNEENPGDEEAKNQVNSESDSDSEESKKPRYRHRLL 1341 Query: 192 --------GASGTRKGKQPHKRKK---KSRKKSLKKPAL---FLEA--ESNTSHSDD--- 232 G SG K +P + K+ ++R+K + + F E+ S S+D Sbjct: 1342 RHKLTVSDGESGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQR 1401 Query: 233 ----SASSSSEESEERDTKKTKRKKR----EKKAHTSVANNEIQERTNKRTNWKVATDER 284 SA + E +R K+ K+++R E + + +N+E +E + + +E Sbjct: 1402 PRTRSAKKAELEENQRSYKQKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEE 1461 Query: 285 SAESSEDD 292 E DD Sbjct: 1462 EEEDENDD 1469 Score = 38.9 bits (89), Expect = 0.005 Identities = 47/189 (24%), Positives = 78/189 (41%), Gaps = 37/189 (19%) Query: 119 EEFETDSDQQDITNGKK---TSPQVK--SSTHESRKHKKSKKSHKKKQKKRSHKKQKKSK 173 ++ +D D +GK+ TS +V+ + T E KH K+K KK Q S +K K Sbjct: 912 QQASASTDGVDKLSGKEQSFTSLEVRKVAETKEKSKHLKTKTC-KKVQDGLSDIAEKFLK 970 Query: 174 KEATDITADSSSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDS 233 K+ +D T++ + S++ GT + K+P KKK ++ E S D Sbjct: 971 KDQSDETSEDDKKQSKK----GTEEKKKPSDFKKK-----------VIKMEQQYESSSDG 1015 Query: 234 ASSSSEESE-----------ERDTKKTKRKKREKKAHTSVANNEIQERTNKRTNWKVATD 282 E E + T ++K ++ + TS +E+ + K T Sbjct: 1016 TEKLPEREEICHFPKGIKQIKNGTTDGEKKSKKIRDKTSKKKDELSDYAEKSTG-----K 1070 Query: 283 ERSAESSED 291 S +SSED Sbjct: 1071 GDSCDSSED 1079 Score = 35.4 bits (80), Expect = 0.060 Identities = 42/199 (21%), Positives = 82/199 (41%), Gaps = 30/199 (15%) Query: 110 HSGYKELYPEEFETDSDQQDITNGKKTSPQVKSSTHESRKHKKSKKS--HKKKQKKRSHK 167 H+ +K LY + +T + + D K+ S S +++K K +K S KKK++ +S Sbjct: 758 HTNHKTLY--DLKTQAGKDDKGKRKRKS-STSGSDFDTKKGKSAKSSIISKKKRQTQSES 814 Query: 168 KQKKSKKE-------------ATDITADSSSEFSEETGASGTRKG--KQPHKRKKKSRKK 212 S+ E T ++ +F ++KG Q HK K S++ Sbjct: 815 SNYDSELEKEIKSMSKIGAARTTKKRIPNTKDFDSSEDEKHSKKGMDNQGHKNLKTSQEG 874 Query: 213 SLKKPALFLEAESNTSHSDDSASSSSEESEERDTKKTK-RKKREKKAHTSVANNEIQERT 271 S ++ + SS+E + ++DT + R + KK S + + + + + Sbjct: 875 S---------SDDAERKQERETFSSAEGTVDKDTTIMELRDRLPKKQQASASTDGVDKLS 925 Query: 272 NKRTNWKVATDERSAESSE 290 K ++ + AE+ E Sbjct: 926 GKEQSFTSLEVRKVAETKE 944 Score = 28.9 bits (63), Expect = 5.6 Identities = 31/168 (18%), Positives = 61/168 (36%), Gaps = 16/168 (9%) Query: 12 RNVIRHTDAHNKIQEESDMWKIRELEKQMEDAYRGTKRKMLPSSSSRMRSDGFDEESQRY 71 R V + QE ++ E E + R K+ L EE+QR Sbjct: 1372 RKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAEL-------------EENQRS 1418 Query: 72 YWRPKNEISGTLEDDFLKAKSWNKKFYDYEANMPDRWGHSGYKELYPEEFETDSDQQDIT 131 Y + K +++D + S NK + E + +E EE E D + Sbjct: 1419 YKQKKKRRRIKVQED---SSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGK 1475 Query: 132 NGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDI 179 KK +K + K+ +++++ +++++ +E +I Sbjct: 1476 GRKKIRKILKDDKLRTETQNALKEEEERRKRIAEREREREKLREVIEI 1523 Score = 28.5 bits (62), Expect = 7.3 Identities = 16/64 (25%), Positives = 33/64 (51%), Gaps = 7/64 (10%) Query: 229 HSDDSASSSSEESEERDTKKTKRKKREKKAHTSVANNEIQERTNKRTNWKVATDERSAES 288 +S + +SSSE+S+ + ++KRK S+ ++ K + + ++ S E+ Sbjct: 59 NSKEEGTSSSEKSKSSGSSRSKRK-------PSIVTKYVESDDEKPLDDETVNEDASNEN 111 Query: 289 SEDD 292 SE+D Sbjct: 112 SEND 115 Score = 28.1 bits (61), Expect = 9.5 Identities = 29/150 (19%), Positives = 64/150 (42%), Gaps = 12/150 (8%) Query: 119 EEFETDSDQQDITNGK--------KTSPQVKSSTHESRKHKKSKKSHKKKQKKRS---HK 167 ++F++ D++ G KTS + S E ++ +++ S + K + Sbjct: 845 KDFDSSEDEKHSKKGMDNQGHKNLKTSQEGSSDDAERKQERETFSSAEGTVDKDTTIMEL 904 Query: 168 KQKKSKKEATDITADSSSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNT 227 + + KK+ + D + S + + + + ++ + K+KS+ K + S+ Sbjct: 905 RDRLPKKQQASASTDGVDKLSGKEQSFTSLEVRKVAETKEKSKHLKTKTCKKVQDGLSDI 964 Query: 228 SHSDDSASSSSEESEERDTKKTKRKKREKK 257 + S E SE+ D K++K+ EKK Sbjct: 965 AEKFLKKDQSDETSED-DKKQSKKGTEEKK 993 >gi|21040326 SON DNA-binding protein isoform F [Homo sapiens] Length = 2426 Score = 51.6 bits (122), Expect = 8e-07 Identities = 44/197 (22%), Positives = 88/197 (44%), Gaps = 17/197 (8%) Query: 102 ANMPDRWGHSGYKELYPEEFETDSDQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQ 161 ++MP+R S +E +++E +D T+ K + + + +K S +S K+ Sbjct: 1773 SSMPERASESSSEE--KDDYEIFVKVKD-THEKSKKNKNRDKGEKEKKRDSSLRSRSKRS 1829 Query: 162 KKRSHKKQKK---SKKEATDITADSSSEFSEETGASGTRKGKQPHKRKKKSR-KKSLKKP 217 K HK +K+ S+ A ++ S S S+ S +R+ ++ + + KSR ++S+ K Sbjct: 1830 KSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKE 1889 Query: 218 ALFLEAESNTSHSDDSASSSSEESEERDTKKTKRKK-----REKKAHTSVANNEIQERTN 272 + + + H S + S RD +KT R + R ++HT + Sbjct: 1890 ----KRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSRSHTP-SRRRRSRSVG 1944 Query: 273 KRTNWKVATDERSAESS 289 +R ++ ++ RS S Sbjct: 1945 RRRSFSISPSRRSRTPS 1961 Score = 40.0 bits (92), Expect = 0.002 Identities = 23/69 (33%), Positives = 38/69 (55%), Gaps = 10/69 (14%) Query: 135 KTSPQVKSSTHESRKHK--KSKKSHKKKQKKRSHKKQKKSKKEAT--------DITADSS 184 +T P + T +S+KHK K+KK KKK+K++ +K+Q + + T D+ +DS Sbjct: 96 QTDPTDEIPTKKSKKHKKHKNKKKKKKKEKEKKYKRQPEESESKTKSHDDGNIDLESDSF 155 Query: 185 SEFSEETGA 193 +F E A Sbjct: 156 LKFDSEPSA 164 Score = 37.4 bits (85), Expect = 0.016 Identities = 35/180 (19%), Positives = 73/180 (40%), Gaps = 15/180 (8%) Query: 77 NEISGTLEDD---FLKAKSWNKKFYDYEANMPDRWGHSGYKELYPEEFETDSDQQDITNG 133 +E S +DD F+K K ++K + ++ G KE + ++ ++ Sbjct: 1780 SESSSEEKDDYEIFVKVKDTHEK------SKKNKNRDKGEKEKKRDSSLRSRSKRSKSSE 1833 Query: 134 KKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITADSSSEFSEETGA 193 K+ + S +RK KSH+ + + RS ++++ + + S E+ Sbjct: 1834 HKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKR 1893 Query: 194 SGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEERDTKKTKRKK 253 S + K +++K+S + +K + A S T S S S R ++ R++ Sbjct: 1894 SPKHRSKSRERKRKRSSSRDNRKT---VRARSRT---PSRRSRSHTPSRRRRSRSVGRRR 1947 Score = 33.1 bits (74), Expect = 0.30 Identities = 19/127 (14%), Positives = 54/127 (42%) Query: 147 SRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITADSSSEFSEETGASGTRKGKQPHKRK 206 SR + ++S K+++KRS K + KS++ ++ + + + + + H Sbjct: 1876 SRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSRSHTPS 1935 Query: 207 KKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEERDTKKTKRKKREKKAHTSVANNE 266 ++ R +S+ + F + S S + S + +++++ R + + + Sbjct: 1936 RRRRSRSVGRRRSFSISPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTP 1995 Query: 267 IQERTNK 273 + R ++ Sbjct: 1996 SRRRRSR 2002 Score = 28.1 bits (61), Expect = 9.5 Identities = 19/69 (27%), Positives = 28/69 (40%), Gaps = 11/69 (15%) Query: 168 KQKKSKKEATDITADSSSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPALFL----EA 223 K+ K + D + E T+K K+ K K K +KK +K + E+ Sbjct: 84 KEGSRKSRCVSVQTDPTDEIP-------TKKSKKHKKHKNKKKKKKKEKEKKYKRQPEES 136 Query: 224 ESNTSHSDD 232 ES T DD Sbjct: 137 ESKTKSHDD 145 >gi|21040314 SON DNA-binding protein isoform B [Homo sapiens] Length = 2303 Score = 51.6 bits (122), Expect = 8e-07 Identities = 44/197 (22%), Positives = 88/197 (44%), Gaps = 17/197 (8%) Query: 102 ANMPDRWGHSGYKELYPEEFETDSDQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQ 161 ++MP+R S +E +++E +D T+ K + + + +K S +S K+ Sbjct: 1773 SSMPERASESSSEE--KDDYEIFVKVKD-THEKSKKNKNRDKGEKEKKRDSSLRSRSKRS 1829 Query: 162 KKRSHKKQKK---SKKEATDITADSSSEFSEETGASGTRKGKQPHKRKKKSR-KKSLKKP 217 K HK +K+ S+ A ++ S S S+ S +R+ ++ + + KSR ++S+ K Sbjct: 1830 KSSEHKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKE 1889 Query: 218 ALFLEAESNTSHSDDSASSSSEESEERDTKKTKRKK-----REKKAHTSVANNEIQERTN 272 + + + H S + S RD +KT R + R ++HT + Sbjct: 1890 ----KRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSRSHTP-SRRRRSRSVG 1944 Query: 273 KRTNWKVATDERSAESS 289 +R ++ ++ RS S Sbjct: 1945 RRRSFSISPSRRSRTPS 1961 Score = 40.0 bits (92), Expect = 0.002 Identities = 23/69 (33%), Positives = 38/69 (55%), Gaps = 10/69 (14%) Query: 135 KTSPQVKSSTHESRKHK--KSKKSHKKKQKKRSHKKQKKSKKEAT--------DITADSS 184 +T P + T +S+KHK K+KK KKK+K++ +K+Q + + T D+ +DS Sbjct: 96 QTDPTDEIPTKKSKKHKKHKNKKKKKKKEKEKKYKRQPEESESKTKSHDDGNIDLESDSF 155 Query: 185 SEFSEETGA 193 +F E A Sbjct: 156 LKFDSEPSA 164 Score = 37.4 bits (85), Expect = 0.016 Identities = 35/180 (19%), Positives = 73/180 (40%), Gaps = 15/180 (8%) Query: 77 NEISGTLEDD---FLKAKSWNKKFYDYEANMPDRWGHSGYKELYPEEFETDSDQQDITNG 133 +E S +DD F+K K ++K + ++ G KE + ++ ++ Sbjct: 1780 SESSSEEKDDYEIFVKVKDTHEK------SKKNKNRDKGEKEKKRDSSLRSRSKRSKSSE 1833 Query: 134 KKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITADSSSEFSEETGA 193 K+ + S +RK KSH+ + + RS ++++ + + S E+ Sbjct: 1834 HKSRKRTSESRSRARKRSSKSKSHRSQTRSRSRSRRRRRSSRSRSKSRGRRSVSKEKRKR 1893 Query: 194 SGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEERDTKKTKRKK 253 S + K +++K+S + +K + A S T S S S R ++ R++ Sbjct: 1894 SPKHRSKSRERKRKRSSSRDNRKT---VRARSRT---PSRRSRSHTPSRRRRSRSVGRRR 1947 Score = 33.1 bits (74), Expect = 0.30 Identities = 19/127 (14%), Positives = 54/127 (42%) Query: 147 SRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITADSSSEFSEETGASGTRKGKQPHKRK 206 SR + ++S K+++KRS K + KS++ ++ + + + + + H Sbjct: 1876 SRSKSRGRRSVSKEKRKRSPKHRSKSRERKRKRSSSRDNRKTVRARSRTPSRRSRSHTPS 1935 Query: 207 KKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEERDTKKTKRKKREKKAHTSVANNE 266 ++ R +S+ + F + S S + S + +++++ R + + + Sbjct: 1936 RRRRSRSVGRRRSFSISPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRTP 1995 Query: 267 IQERTNK 273 + R ++ Sbjct: 1996 SRRRRSR 2002 Score = 28.1 bits (61), Expect = 9.5 Identities = 19/69 (27%), Positives = 28/69 (40%), Gaps = 11/69 (15%) Query: 168 KQKKSKKEATDITADSSSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPALFL----EA 223 K+ K + D + E T+K K+ K K K +KK +K + E+ Sbjct: 84 KEGSRKSRCVSVQTDPTDEIP-------TKKSKKHKKHKNKKKKKKKEKEKKYKRQPEES 136 Query: 224 ESNTSHSDD 232 ES T DD Sbjct: 137 ESKTKSHDD 145 >gi|38788333 remodeling and spacing factor 1 [Homo sapiens] Length = 1441 Score = 51.2 bits (121), Expect = 1e-06 Identities = 43/190 (22%), Positives = 92/190 (48%), Gaps = 17/190 (8%) Query: 118 PEEFETDSDQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKR--SHKKQKKSKKE 175 P+E E D D ++ S +++ H SR ++S++ +K KK+ ++++S++ Sbjct: 1126 PDESEEDPPSNDDSDTDFCSRRLRR--HPSRPMRQSRRLRRKTPKKKYSDDDEEEESEEN 1183 Query: 176 ATDITADSSSEFSEETGASGTRKGKQPHKR--------KKKSRKKSLKKPALFLEAES-- 225 + D +D S +FS++ + R+ ++ KR + +KSL++ Sbjct: 1184 SRDSESDFSDDFSDDFVETRRRRSRRNQKRQINYKEDSESDGSQKSLRRGKEIRRVHKRR 1243 Query: 226 -NTSHSDDSASSSSEESEE--RDTKKTKRKKREKKAHTSVANNEIQERTNKRTNWKVATD 282 ++S S++S S + E +E +++K++ RK+ S A+ E +E K + ++ Sbjct: 1244 LSSSESEESYLSKNSEDDELAKESKRSVRKRGRSTDEYSEADEEEEEEEGKPSRKRLHRI 1303 Query: 283 ERSAESSEDD 292 E E S D+ Sbjct: 1304 ETDEEESCDN 1313 Score = 43.1 bits (100), Expect = 3e-04 Identities = 49/235 (20%), Positives = 93/235 (39%), Gaps = 43/235 (18%) Query: 34 RELEKQMEDAYRGTKRKMLPSSSSRMRSDGFDEESQRYYWRPKNEISGTLEDDFLKAKSW 93 R L + R ++R + + D +EES+ +++ S DDF++ + Sbjct: 1146 RRLRRHPSRPMRQSRRLRRKTPKKKYSDDDEEEESEENSRDSESDFSDDFSDDFVETRRR 1205 Query: 94 NKKFYDYEANMPDRWGHSGYKEL-YPEEFETDSDQQDITNGKKTSPQVK-----SSTHES 147 + + +++ Y E+ E+D Q+ + GK+ K S + ES Sbjct: 1206 RSR-------------RNQKRQINYKEDSESDGSQKSLRRGKEIRRVHKRRLSSSESEES 1252 Query: 148 RKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITADSSSEFSEETGASGTRKGKQPHKRKK 207 K S+ K+ KRS +K+ +S TD +++ E EE G Sbjct: 1253 YLSKNSEDDELAKESKRSVRKRGRS----TDEYSEADEEEEEEEG--------------- 1293 Query: 208 KSRKKSLKKPALFLEAESNTSHSDDSASSSSEE-----SEERDTKKTKRKKREKK 257 K +K L + E + +H D + + + SE+ TKK R + +++ Sbjct: 1294 KPSRKRLHRIETDEEESCDNAHGDANQPARDSQPRVLPSEQESTKKPYRIESDEE 1348 Score = 37.0 bits (84), Expect = 0.021 Identities = 34/177 (19%), Positives = 68/177 (38%), Gaps = 17/177 (9%) Query: 115 ELYPEEFETDSDQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKK 174 +L PEE T S+ +IT+ ++ + SRK K + + + K +K+ +K Sbjct: 709 KLVPEEETTASENTEITSERQKEGIKLTIRISSRKKKPDSPPKVLEPENKQEKTEKEEEK 768 Query: 175 EATDITADSSSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSA 234 T S S T + ++ K++ + + +E ES D Sbjct: 769 TNVGRTLRRSPRISRPTAKVAEIRDQKADKKRGEGEDE--------VEEESTALQKTDKK 820 Query: 235 SSSSEESEERDTKKTKRKKREKKAHTSVANNEIQERTNKRTNWKVATDERSAESSED 291 + ++ ++K +K K + K T + R WK ++++ S S + Sbjct: 821 EILKKSEKDTNSKVSKVKPKGKVRWTG---------SRTRGRWKYSSNDESEGSGSE 868 Score = 36.6 bits (83), Expect = 0.027 Identities = 31/135 (22%), Positives = 63/135 (46%), Gaps = 19/135 (14%) Query: 124 DSDQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITADS 183 +S QQD N + SP + E + KK +++ K++++K S K KS+++ D+ S Sbjct: 216 NSSQQD--NSSRESPSL-----EDEETKKEEETPKQEEQKESEKM--KSEEQPMDLENRS 266 Query: 184 SSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEE 243 ++ EET K++K+ K+ +K P + + + + +S + Sbjct: 267 TANVLEETTV----------KKEKEDEKELVKLPVIVKLEKPLPENEEKKIIKEESDSFK 316 Query: 244 RDTKKTKRKKREKKA 258 + K K + +E +A Sbjct: 317 ENVKPIKVEVKECRA 331 Score = 30.4 bits (67), Expect = 1.9 Identities = 42/194 (21%), Positives = 63/194 (32%), Gaps = 45/194 (23%) Query: 143 STHESRKHKKSKKSHKKKQKKRSHKKQK------------------KSKKEATDITADSS 184 S + K K SKKS ++RS + +K KEA Sbjct: 990 SEDQEEKKKDSKKSKANLLERRSTRTRKCISYRFDEFDEAIDEAIEDDIKEADGGGVGRG 1049 Query: 185 SEFSEETGASGT----------RKGKQPHK-----RKKKSRKKSLKKPALFLEAESNTSH 229 + S TG G ++ K+P + RKK+ R L + E ES Sbjct: 1050 KDISTITGHRGKDISTILDEERKENKRPQRAAAARRKKRRRLNDLDSDSNLDEEESEDEF 1109 Query: 230 ------------SDDSASSSSEESEERDTKKTKRKKREKKAHTSVANNEIQERTNKRTNW 277 SD++ S E+ D T R + H S + + K Sbjct: 1110 KISDGSQDEFVVSDENPDESEEDPPSNDDSDTDFCSRRLRRHPSRPMRQSRRLRRKTPKK 1169 Query: 278 KVATDERSAESSED 291 K + D+ ES E+ Sbjct: 1170 KYSDDDEEEESEEN 1183 Score = 28.5 bits (62), Expect = 7.3 Identities = 31/134 (23%), Positives = 64/134 (47%), Gaps = 13/134 (9%) Query: 119 EEFETDSDQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATD 178 E+ E + ++ ++ + SP++ SR K + +K K+ + + + ++E+T Sbjct: 760 EKTEKEEEKTNVGRTLRRSPRI------SRPTAKVAEIRDQKADKKRGEGEDEVEEESTA 813 Query: 179 ITADSSSEF---SEETGASGTRKGKQPHK-RKKKSRKKSLKKPALFLEAESNTSHSDDSA 234 + E SE+ S K K K R SR + K + E+E + S + + Sbjct: 814 LQKTDKKEILKKSEKDTNSKVSKVKPKGKVRWTGSRTRGRWKYSSNDESEGSGS---EKS 870 Query: 235 SSSSEESEERDTKK 248 S++SEE EE+++++ Sbjct: 871 SAASEEEEEKESEE 884 >gi|148746195 trichohyalin [Homo sapiens] Length = 1943 Score = 51.2 bits (121), Expect = 1e-06 Identities = 62/289 (21%), Positives = 124/289 (42%), Gaps = 30/289 (10%) Query: 23 KIQEESDMWKIRELEKQMEDAYRGTKRKMLPSSSSRMRSDGFDEESQR----YYWRPKNE 78 ++Q+E + E EK+ ++ R + + + R + +E QR + W P+ E Sbjct: 1175 ELQQEEEQLLREEQEKRRQERERQYREE--EELQRQKRKQRYRDEDQRSDLKWQWEPEKE 1232 Query: 79 ISGTLEDDFLKAKSWNKKFYDYE-ANMPDRWGHSGYKELYPEEFETDSDQQDITNGKKTS 137 + + K + N++F E + + DR + L E+ E D +Q+ ++ Sbjct: 1233 NAVRDNKVYCKGRE-NEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDR 1291 Query: 138 --PQVKSSTHESRKHKK--SKKSHKKKQKKRSHKKQKKSKKEATDITADSSSEFSEETGA 193 P+ + E +K K +KS ++KQ R +++K+ ++E + +F EE Sbjct: 1292 HFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQE-------TDRKFREEEQL 1344 Query: 194 SGTRKGKQPHKRKKKSRK------KSLKKPALFLEAESNTSHSDDSASSSSEESEER--D 245 R+ +QP +R+++ RK + ++ FLE E + EE + R + Sbjct: 1345 LQERE-EQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQE 1403 Query: 246 TKKTKRKKREKKAHTSVANNEIQERTNK--RTNWKVATDERSAESSEDD 292 ++ R+ R++K QER K +V ER + E++ Sbjct: 1404 REQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEE 1452 Score = 38.5 bits (88), Expect = 0.007 Identities = 44/256 (17%), Positives = 104/256 (40%), Gaps = 26/256 (10%) Query: 23 KIQEESDMWKIRELEKQMEDAYRGTKRKMLPSSSSRMRSDGFDEESQRYYWRPKNEISGT 82 +++ E + + ++L ++ E+ K + R E+ +R W + E + Sbjct: 412 QLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKR-----EQEERRDWLKREEETER 466 Query: 83 LEDDFLKAKSWNKKFYDYEANMPDRWGHSGYKELYPEEFETDSDQQDITNGKKTSPQVKS 142 E + + K K+ D E +RW L EE E Q+ + Q++ Sbjct: 467 HEQE--RRKQQLKR--DQEEERRERW-------LKLEEEERREQQE------RREQQLRR 509 Query: 143 STHESRKH--KKSKKSHKKKQKKRSHKKQKKSKKEATD--ITADSSSEFSEETGASGTRK 198 E R+ K+ ++ + +Q+ RS ++ ++ ++E + + + +E ++ Sbjct: 510 EQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKR 569 Query: 199 GKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEERDTKKTKRKKREKKA 258 ++ + + R++ ++ L E E E EER ++ KR++ E++ Sbjct: 570 EQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEER 629 Query: 259 HTSVANNEIQERTNKR 274 + +E QE ++ Sbjct: 630 RQQLLKSEEQEERRQQ 645 Score = 37.7 bits (86), Expect = 0.012 Identities = 37/244 (15%), Positives = 96/244 (39%), Gaps = 23/244 (9%) Query: 19 DAHNKIQEESDMWKIRELEKQMEDAYRGTKRKMLPSSSSRMRSDGFDEESQRYYWRPKNE 78 + ++ + K + E+Q+ RG +R+ R E ++ R + + Sbjct: 1519 EEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERD 1578 Query: 79 ISGTLEDDFLKAKSWNKKFYDYEANMPDRWGHSGYKELYPEEFETDS------DQQDITN 132 LE+ ++ + +KF + E + + G ++ +F D ++Q + Sbjct: 1579 RKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHR 1638 Query: 133 GKKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITADSSSEFSEETG 192 ++ ++ R+ ++ + H + +K R ++ + +E + +F EE Sbjct: 1639 QERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREE-- 1696 Query: 193 ASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEERDTKKTKRK 252 +Q +R+++ RK FL+ E + EE ++T++ + + Sbjct: 1697 -------EQQLRRQERERK--------FLQEEQQLRRQELERKFREEEQLRQETEQEQLR 1741 Query: 253 KREK 256 ++E+ Sbjct: 1742 RQER 1745 Score = 37.0 bits (84), Expect = 0.021 Identities = 47/288 (16%), Positives = 110/288 (38%), Gaps = 52/288 (18%) Query: 26 EESDMWKIRELEKQMEDAYRGTKRKMLPSSSSRMRSDGFDEESQRYYWRPKNEISGTLED 85 EE ++ + E+Q E + +R+ R++ + EE +R R K E + Sbjct: 626 EEERRQQLLKSEEQEERRQQQLRREQQERREQRLKRE---EEEERLEQRLKREHEEERRE 682 Query: 86 DFLKAKSWNKKFYDYEANMPDRWGHSGYKELYPEEFETDSDQQDITNGKKTSPQVKSSTH 145 L + + ++ +P K + E E D+ Q + + + + Sbjct: 683 QELAEEEQEQARERIKSRIP--------KWQWQLESEADARQSKVYSRPRKQEGQRRRQE 734 Query: 146 ESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITADSSSEFSEETGASGT--------- 196 + K ++ + + ++++R+H++Q++ +++ D T +E E G Sbjct: 735 QEEKRRRRESELQWQEEERAHRQQQE-EEQRRDFTWQWQAEEKSERGRQRLSARPPLREQ 793 Query: 197 --------------------RKGKQPHKRKKKSRKKSL-----------KKPALFLEAES 225 + K+ +R+++ R+K L ++ A L+ E Sbjct: 794 RERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEE 853 Query: 226 NTSHSDDSASSSSEESEERDTKKTKRKKREKKAHTSVANNEIQERTNK 273 + D S E+ ++ + ++R+++ HT A +QE+ K Sbjct: 854 DGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRK 901 Score = 36.2 bits (82), Expect = 0.035 Identities = 47/297 (15%), Positives = 114/297 (38%), Gaps = 23/297 (7%) Query: 16 RHT-DAHNKIQEE--SDMWKIRELEKQMEDAYRGTKRKMLPSSSSRMRSDGFDEESQRYY 72 RHT A +QE+ + ++E E++++ R +R+ R EE Q Sbjct: 886 RHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLR 945 Query: 73 WRPKNEISGTLEDDFLKAKSWNKKFYDYEANMPDRWGHSGYKELYPEEFETDSDQQDITN 132 + E + K K +K P++ ++ Y EE E +++ + Sbjct: 946 EEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLR 1005 Query: 133 GKKTSPQVKSSTHESRKHKKSKKSH----KKKQKKRSHKKQKKSKKEATDITADSSSEFS 188 ++ + + + RK + ++ +++++KR +++++ +E ++ + Sbjct: 1006 EEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLG 1065 Query: 189 EETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEES------- 241 EE TR+ ++ ++ +K + ++ L E + EE Sbjct: 1066 EERE---TRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQ 1122 Query: 242 ------EERDTKKTKRKKREKKAHTSVANNEIQERTNKRTNWKVATDERSAESSEDD 292 E+R ++ +R+ RE++ ++E KR ++ R E + + Sbjct: 1123 LLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQE 1179 Score = 35.4 bits (80), Expect = 0.060 Identities = 34/244 (13%), Positives = 91/244 (37%), Gaps = 15/244 (6%) Query: 58 RMRSDGFDEESQRYYWRPKNEISGTLEDDFLKAKSWNKKFYDYEANMPDRWGHSGYKELY 117 R R D +E + WR + + E+ + + ++ E + +EL Sbjct: 231 RERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLER---QELR 287 Query: 118 PEEFETDSDQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEAT 177 E E + QQ + ++ + + E ++ ++ ++ +++Q++R ++ ++ ++E Sbjct: 288 RERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERR 347 Query: 178 DITADSSSEFS-----------EETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESN 226 + E EE R+ +Q + ++ R++ L++ L E Sbjct: 348 EQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQ-LRREQQ 406 Query: 227 TSHSDDSASSSSEESEERDTKKTKRKKREKKAHTSVANNEIQERTNKRTNWKVATDERSA 286 E++ ++ + ++ E+K ++ +R +W +E Sbjct: 407 LRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETER 466 Query: 287 ESSE 290 E Sbjct: 467 HEQE 470 Score = 35.0 bits (79), Expect = 0.078 Identities = 39/234 (16%), Positives = 96/234 (41%), Gaps = 23/234 (9%) Query: 25 QEESDMWKIRELEKQMEDAYRGTKRK---------MLPSSSSRMRSDGFDEESQRYYWRP 75 +E + RE EK++E R + K +L R + E+ +R R Sbjct: 543 EERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRL 602 Query: 76 KNEISGTLEDDFLKAKSWNKKFYDYEANMPDRWGHSGYKELYPEEFETDSDQQDITNGK- 134 K E LE + + + ++ + E ++L E + + QQ + + Sbjct: 603 KREEVERLEQEERREQRLKREEPEEERR----------QQLLKSEEQEERRQQQLRREQQ 652 Query: 135 -KTSPQVKSSTHESRKHKKSKKSHKKKQKKR--SHKKQKKSKKEATDITADSSSEFSEET 191 + ++K E R ++ K+ H+++++++ + ++Q+++++ + E Sbjct: 653 ERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEA 712 Query: 192 GASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEERD 245 A ++ +P K++ + R++ ++ E+E + + EE + RD Sbjct: 713 DARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRD 766 Score = 34.3 bits (77), Expect = 0.13 Identities = 42/276 (15%), Positives = 104/276 (37%), Gaps = 39/276 (14%) Query: 16 RHTDAHNKIQEESDMWKIRELEKQMEDAYRGTKRKMLPSSSSRMRSDGFDEESQRYYWRP 75 R + + EE + + RE +Q+++ G + S R D Q++ W+ Sbjct: 825 REREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRD------QKWRWQL 878 Query: 76 KNEISGTLEDDFLKAKSWNKKFYDYEANMPDRWGHSGYKELYPEEFETDSDQQDITNGKK 135 + E + K + + + + +EL EE E Q+ ++ Sbjct: 879 EEERKRRRHTLYAKPALQEQLRKEQQLLQEEE------EELQREEREKRRRQEQ---ERQ 929 Query: 136 TSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITADSSSEFSEETGASG 195 + + E + ++ ++ ++++++R ++K KK +++ + Sbjct: 930 YREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLL--------------- 974 Query: 196 TRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEERDTKKTKRKKRE 255 G++P KR+++ R+K + E E + E+ ++ ++ RKK E Sbjct: 975 ---GEEPEKRRRQEREKK------YREEEELQQEEEQLLREEREKRRRQEWERQYRKKDE 1025 Query: 256 KKAHTSVANNEIQERTNKRTNWKVATDERSAESSED 291 + E +E+ + + +E + E+ Sbjct: 1026 LQQEEEQLLREEREKRRLQERERQYREEEELQQEEE 1061 Score = 32.3 bits (72), Expect = 0.51 Identities = 31/233 (13%), Positives = 89/233 (38%), Gaps = 17/233 (7%) Query: 25 QEESDMWKIRELEKQMEDAYRGTKRKMLPSSSSRMRSDGFDEESQRYYWRPKNEISGTLE 84 +EE W+ RE + E+ K+ R R +EE R LE Sbjct: 240 EEEEKEWRKRETVLRKEE------EKLQEEEPQRQRELQEEEEQLR-----------KLE 282 Query: 85 DDFLKAKSWNKKFYDYEANMPDRWGHSGYKELYPEEFETDSDQQDITNGKKTSPQVKSST 144 L+ + ++ + +E ++ E Q+ ++ Q Sbjct: 283 RQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRRE 342 Query: 145 HESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITADSSSEFSEETGASGTRKGKQPHK 204 E R+ ++ ++ +++++++ +++++ ++ + + ++ + +Q + Sbjct: 343 QEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLR 402 Query: 205 RKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEERDTKKTKRKKREKK 257 R+++ R++ + L E + + +ER ++ KR++ E++ Sbjct: 403 REQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERR 455 Score = 29.3 bits (64), Expect = 4.3 Identities = 34/250 (13%), Positives = 96/250 (38%), Gaps = 32/250 (12%) Query: 25 QEESDMWKIRELEKQMEDAYRGTKRKMLPSSSSRMRSDGFDEESQRYYWRPKNEISGTLE 84 ++E D + ++Q+E+ G +R+ R ++G +E+S++ + + E Sbjct: 114 RQEEDQRRFEPRDRQLEEE-PGQRRRQKRQEQERELAEG-EEQSEKQERLEQRDRQRRDE 171 Query: 85 DDFLKAKSWNKKFYDYEANMPDRWGHSGYKELYPEEFETDSDQQDITNGKKTSPQVKSST 144 + + + + W ++ EE + +Q G +T Sbjct: 172 ELWRQRQEWQER----------------------EERRAEEEQLQSCKGHETE------- 202 Query: 145 HESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITADSSSEFSEETGASGTRKGKQPHK 204 E ++ ++ + +++ +++++ ++E D E + RK ++ + Sbjct: 203 -EFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQ 261 Query: 205 RKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEERDTKKTKRKKREKKAHTSVAN 264 ++ R++ L++ L + ++ R ++ +RK+ E++ Sbjct: 262 EEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEER 321 Query: 265 NEIQERTNKR 274 E QER ++ Sbjct: 322 REQQERREQQ 331 >gi|166235169 PRP38 pre-mRNA processing factor 38 (yeast) domain containing B [Homo sapiens] Length = 546 Score = 51.2 bits (121), Expect = 1e-06 Identities = 52/242 (21%), Positives = 98/242 (40%), Gaps = 25/242 (10%) Query: 34 RELEKQMEDAYRGTKRKMLPSSSSRMRSDGFDEESQRYYWRPKNEISGTLEDDFLKAKSW 93 RELE++ E + K R RS E +R R ++ D + Sbjct: 293 RELEREKERQRLEREAKEREKERRRSRSIDRGLERRRSRSRERHRSRSRSRD-----RKG 347 Query: 94 NKKFYDYEANMPDRWGHSGYKELYPEEFETDSDQQDITNGKKTSPQVKSSTHESRKHKKS 153 +++ D E + G ++ Y +E + +++ + +++ Q E +KHK+ Sbjct: 348 DRRDRDREREKENERGRRRDRD-YDKERGNEREKERERSRERSKEQRSRGEVEEKKHKED 406 Query: 154 KKSHKKKQKKRSHKKQKKSKKEATDITADSSSEFSEETGA-SGTRKGKQPHKRKKKSRKK 212 K + + KR KK+KK + + S S G S +R ++ K K +S++K Sbjct: 407 KDDRRHRDDKRDSKKEKKHSRSRSRERKHRSRSRSRNAGKRSRSRSKEKSSKHKNESKEK 466 Query: 213 SLKKPALFLEAESNTSHSDDSASSSSEESEERDTKKTKRKKREKKAHTSVANNEIQERTN 272 S K+ + S + DS S + +K++++ R K ER++ Sbjct: 467 SNKR------SRSGSQGRTDSVEKSKKREHSPSKEKSRKRSRSK------------ERSH 508 Query: 273 KR 274 KR Sbjct: 509 KR 510 Score = 50.8 bits (120), Expect = 1e-06 Identities = 51/245 (20%), Positives = 105/245 (42%), Gaps = 23/245 (9%) Query: 25 QEESDMWKIRELEKQMEDAYRGTKRKMLPSSSSRMRS-DGFDEESQRYYWRPKNEISGTL 83 + E + + R +++ +E ++ + S SR R D D + +R +NE Sbjct: 310 EREKERRRSRSIDRGLERRRSRSRERHRSRSRSRDRKGDRRDRDRER---EKENERGRRR 366 Query: 84 EDDFLKAKSWNKKFYDYEANMPDRWGHSGYKELYPEEFETDSDQQDITNGKKTSPQVKS- 142 + D+ K + N++ + E + E+ ++ + D D + + K+ S + K Sbjct: 367 DRDYDKERG-NEREKERERSRERSKEQRSRGEVEEKKHKEDKDDRRHRDDKRDSKKEKKH 425 Query: 143 --STHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITADSSSEFSEETGASGTR--- 197 S RKH+ +S ++ RS K+K SK + + S E S + SG++ Sbjct: 426 SRSRSRERKHRSRSRSRNAGKRSRSRSKEKSSKHK------NESKEKSNKRSRSGSQGRT 479 Query: 198 ------KGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEERDTKKTKR 251 K ++ K+KSRK+S K S++ D +S E+++++ + Sbjct: 480 DSVEKSKKREHSPSKEKSRKRSRSKERSHKRDHSDSKDQSDKHDRRRSQSIEQESQEKQH 539 Query: 252 KKREK 256 K +++ Sbjct: 540 KNKDE 544 Score = 50.1 bits (118), Expect = 2e-06 Identities = 34/152 (22%), Positives = 71/152 (46%), Gaps = 7/152 (4%) Query: 141 KSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDIT-ADSSSEFSEETGASGTRKG 199 K +E K ++ + K+Q+ R ++KK K++ D D + +E S +R Sbjct: 372 KERGNEREKERERSRERSKEQRSRGEVEEKKHKEDKDDRRHRDDKRDSKKEKKHSRSRSR 431 Query: 200 KQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEERDTKKTKRKKREKKAH 259 ++ H + +SR ++ K + E ++ H ++S S++ S +T ++ KK Sbjct: 432 ERKH--RSRSRSRNAGKRSRSRSKEKSSKHKNESKEKSNKRSRSGSQGRTDSVEKSKKRE 489 Query: 260 TSVANNEIQERTNKRTNWKVATDERSAESSED 291 S + +E++ KR+ K + +R S+D Sbjct: 490 HSPS----KEKSRKRSRSKERSHKRDHSDSKD 517 Score = 43.9 bits (102), Expect = 2e-04 Identities = 37/173 (21%), Positives = 73/173 (42%), Gaps = 6/173 (3%) Query: 118 PEEFETDSDQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEAT 177 P + + DQQ T +K K E +H + ++S ++ + ++S+ + Sbjct: 222 PVPVQKNIDQQIKTRPRKIKKDGKEGAEEIDRHVERRRSRSPRRSLSPRRSPRRSRSRSH 281 Query: 178 DITADSSSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKP-ALFLEAESNTSHSDDSASS 236 SS F E K +Q +R+ K R+K ++ ++ E S S + S Sbjct: 282 HREGHGSSSFDREL---EREKERQRLEREAKEREKERRRSRSIDRGLERRRSRSRERHRS 338 Query: 237 SSEESEERDTKKTKRKKREKKAHTSVANNE--IQERTNKRTNWKVATDERSAE 287 S + + ++ + ++REK+ + +ER N+R + + ERS E Sbjct: 339 RSRSRDRKGDRRDRDREREKENERGRRRDRDYDKERGNEREKERERSRERSKE 391 Score = 32.0 bits (71), Expect = 0.66 Identities = 41/199 (20%), Positives = 81/199 (40%), Gaps = 30/199 (15%) Query: 34 RELEKQMEDAYRGTKRKMLPSSSSRMRSDGFDEESQRYYWRPKNEIS-GTLEDDFLKAKS 92 RE EK+ E RG +R + R + ++E +R R K + S G +E+ K Sbjct: 354 REREKENE---RGRRRDR---DYDKERGNEREKERERSRERSKEQRSRGEVEEKKHKEDK 407 Query: 93 WNKKFYDYEANMPDRWGHSGYKELYPEEFETDSDQQDITNGKKTSPQVKSSTHESRKHKK 152 +++ D + + HS + + + S ++ ++ + KSS H++ +K Sbjct: 408 DDRRHRDDKRDSKKEKKHSRSRSR-ERKHRSRSRSRNAGKRSRSRSKEKSSKHKNESKEK 466 Query: 153 S-------------------KKSH---KKKQKKRSHKKQKKSKKEATDITADSSSEFSEE 190 S K+ H K+K +KRS K++ K++ +D S Sbjct: 467 SNKRSRSGSQGRTDSVEKSKKREHSPSKEKSRKRSRSKERSHKRDHSDSKDQSDKHDRRR 526 Query: 191 TGASGTRKGKQPHKRKKKS 209 + + ++ HK K ++ Sbjct: 527 SQSIEQESQEKQHKNKDET 545 Score = 31.2 bits (69), Expect = 1.1 Identities = 23/92 (25%), Positives = 42/92 (45%), Gaps = 4/92 (4%) Query: 204 KRKKKSRKKSLKKPALFLEAESNTSHSDDSASSS----SEESEERDTKKTKRKKREKKAH 259 +R+ +S ++SL + S + H + SSS E +ER + + K+REK+ Sbjct: 257 RRRSRSPRRSLSPRRSPRRSRSRSHHREGHGSSSFDRELEREKERQRLEREAKEREKERR 316 Query: 260 TSVANNEIQERTNKRTNWKVATDERSAESSED 291 S + + ER R+ + + RS + D Sbjct: 317 RSRSIDRGLERRRSRSRERHRSRSRSRDRKGD 348 >gi|50409738 SRp25 nuclear protein isoform 3 [Homo sapiens] Length = 352 Score = 51.2 bits (121), Expect = 1e-06 Identities = 32/125 (25%), Positives = 59/125 (47%), Gaps = 6/125 (4%) Query: 150 HKKSKKSHKKKQKKRSHKKQKKSKKEATDITADSSSEFSEETGASGTRKGKQPHKRKKKS 209 H S+K + + + R +K+ KK D + + S+ S+ AS ++ K+K + Sbjct: 126 HVGSRKRSRSRSRSRGRGSEKRKKKSRKDTSRNCSASTSQGRKASTAPGAEERSKQKARR 185 Query: 210 RKKSLKKPALFLEAESNTSHSDDSASSSS------EESEERDTKKTKRKKREKKAHTSVA 263 R +S + + S++S S S+SSS + ++R KK KRKK +KK Sbjct: 186 RTRSSSSSSSSSSSSSSSSSSSSSSSSSDGRKKRGKYKDKRRKKKKKRKKLKKKGKEKAE 245 Query: 264 NNEIQ 268 +++ Sbjct: 246 AQQVE 250 Score = 47.4 bits (111), Expect = 2e-05 Identities = 32/115 (27%), Positives = 55/115 (47%), Gaps = 11/115 (9%) Query: 143 STHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITADSSSEFSEETGASGTRKGKQP 202 S SR +S+ +K+KK+S K + + +A +S T + KQ Sbjct: 129 SRKRSRSRSRSRGRGSEKRKKKSRKDTSR------NCSASTSQGRKASTAPGAEERSKQK 182 Query: 203 HKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESEERDTKKTKRKKREKK 257 +R+ +S S + S++S S S+SSSS+ ++R K KR+K++KK Sbjct: 183 ARRRTRSSSSSSSS-----SSSSSSSSSSSSSSSSSDGRKKRGKYKDKRRKKKKK 232 Score = 44.7 bits (104), Expect = 1e-04 Identities = 37/137 (27%), Positives = 63/137 (45%), Gaps = 7/137 (5%) Query: 125 SDQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKK-KQKKRSHKKQKKSKKEATDITADS 183 S+++ + K TS +ST + RK + + ++ KQK R + S ++ ++ S Sbjct: 144 SEKRKKKSRKDTSRNCSASTSQGRKASTAPGAEERSKQKARRRTRSSSSSSSSSSSSSSS 203 Query: 184 SSEFSEETGASGTRK-GKQPHKRKKK-----SRKKSLKKPALFLEAESNTSHSDDSASSS 237 SS S + + G +K GK KR+KK KK K+ A + E+ S D S Sbjct: 204 SSSSSSSSSSDGRKKRGKYKDKRRKKKKKRKKLKKKGKEKAEAQQVEALPGPSLDQWHRS 263 Query: 238 SEESEERDTKKTKRKKR 254 + E E+ ++K R Sbjct: 264 AGEEEDGPVLTDEQKSR 280 Score = 38.1 bits (87), Expect = 0.009 Identities = 31/152 (20%), Positives = 61/152 (40%), Gaps = 9/152 (5%) Query: 123 TDSDQQDITNGKKTSPQVKSSTHESRKHKKSKKSHKKKQKKRSHKKQKKSKKEATDITAD 182 + S ++ +S SS ++ K K KKK+K++ KK+ K K EA + A Sbjct: 193 SSSSSSSSSSSSSSSSSSSSSDGRKKRGKYKDKRRKKKKKRKKLKKKGKEKAEAQQVEAL 252 Query: 183 SSSEFSEETGASGTRKGKQPHKRKKKSRKKSLKKPALFLEAESNTSHSDDSASSSSEESE 242 + ++G + ++KSR +++K T D+ S + Sbjct: 253 PGPSLDQWHRSAGEEEDGPVLTDEQKSRIQAMK---------PMTKEEWDARQSIIRKVV 303 Query: 243 ERDTKKTKRKKREKKAHTSVANNEIQERTNKR 274 + +T +T+ K + + + E NK+ Sbjct: 304 DPETGRTRLIKGDGEVLEEIVTKERHREINKQ 335 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.302 0.118 0.322 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 10,964,861 Number of Sequences: 37866 Number of extensions: 508867 Number of successful extensions: 12424 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 482 Number of HSP's successfully gapped in prelim test: 708 Number of HSP's that attempted gapping in prelim test: 4308 Number of HSP's gapped (non-prelim): 4598 length of query: 292 length of database: 18,247,518 effective HSP length: 101 effective length of query: 191 effective length of database: 14,423,052 effective search space: 2754802932 effective search space used: 2754802932 T: 11 A: 40 X1: 17 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 43 (21.8 bits) S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.