Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 109134336
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|109134336 SH3-domain binding protein 5 (BTK-associated)
isoform a [Homo sapiens]
(455 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|109134336 SH3-domain binding protein 5 (BTK-associated) isofo... 884 0.0
gi|109134344 SH3-domain binding protein 5 (BTK-associated) isofo... 584 e-167
gi|24308303 SH3-binding domain protein 5-like [Homo sapiens] 211 8e-55
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 63 6e-10
gi|114155140 tropomyosin 3 isoform 1 [Homo sapiens] 57 5e-08
gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo... 56 6e-08
gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo ... 55 1e-07
gi|93102364 SWAP-70 protein [Homo sapiens] 55 2e-07
gi|115511012 coiled-coil domain containing 136 [Homo sapiens] 55 2e-07
gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo... 53 5e-07
gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo... 53 5e-07
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 53 7e-07
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 53 7e-07
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 53 7e-07
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 53 7e-07
gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta ... 53 7e-07
gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [... 53 7e-07
gi|87298937 centrosomal protein 110kDa [Homo sapiens] 53 7e-07
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 52 9e-07
gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [H... 52 9e-07
gi|4507651 tropomyosin 4 isoform 2 [Homo sapiens] 52 1e-06
gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens] 52 1e-06
gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens] 52 1e-06
gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens] 52 1e-06
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 51 2e-06
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m... 51 2e-06
gi|4505257 moesin [Homo sapiens] 51 2e-06
gi|63252898 tropomyosin 1 alpha chain isoform 1 [Homo sapiens] 51 2e-06
gi|156104908 myosin heavy chain 6 [Homo sapiens] 51 2e-06
gi|4504063 golgin 97 [Homo sapiens] 51 2e-06
>gi|109134336 SH3-domain binding protein 5 (BTK-associated) isoform
a [Homo sapiens]
Length = 455
Score = 884 bits (2284), Expect = 0.0
Identities = 455/455 (100%), Positives = 455/455 (100%)
Query: 1 MDAALKRSRSEEPAEILPPARDEEEEEEEGMEQGLEEEEEVDPRIQGELEKLNQSTDDIN 60
MDAALKRSRSEEPAEILPPARDEEEEEEEGMEQGLEEEEEVDPRIQGELEKLNQSTDDIN
Sbjct: 1 MDAALKRSRSEEPAEILPPARDEEEEEEEGMEQGLEEEEEVDPRIQGELEKLNQSTDDIN 60
Query: 61 RRETELEDARQKFRSVLVEATVKLDELVKKIGKAVEDSKPYWEARRVARQAQLEAQKATQ 120
RRETELEDARQKFRSVLVEATVKLDELVKKIGKAVEDSKPYWEARRVARQAQLEAQKATQ
Sbjct: 61 RRETELEDARQKFRSVLVEATVKLDELVKKIGKAVEDSKPYWEARRVARQAQLEAQKATQ 120
Query: 121 DFQRATEVLRAAKETISLAEQRLLEDDKRQFDSAWQEMLNHATQRVMEAEQTKTRSELVH 180
DFQRATEVLRAAKETISLAEQRLLEDDKRQFDSAWQEMLNHATQRVMEAEQTKTRSELVH
Sbjct: 121 DFQRATEVLRAAKETISLAEQRLLEDDKRQFDSAWQEMLNHATQRVMEAEQTKTRSELVH 180
Query: 181 KETAARYNAAMGRMRQLEKKLKRAINKSKPYFELKAKYYVQLEQLKKTVDDLQAKLTLAK 240
KETAARYNAAMGRMRQLEKKLKRAINKSKPYFELKAKYYVQLEQLKKTVDDLQAKLTLAK
Sbjct: 181 KETAARYNAAMGRMRQLEKKLKRAINKSKPYFELKAKYYVQLEQLKKTVDDLQAKLTLAK 240
Query: 241 GEYKMALKNLEMISDEIHERRRSSAMGPRGCGVGAEGSSTSVEDLPGSKPEPDAISVASE 300
GEYKMALKNLEMISDEIHERRRSSAMGPRGCGVGAEGSSTSVEDLPGSKPEPDAISVASE
Sbjct: 241 GEYKMALKNLEMISDEIHERRRSSAMGPRGCGVGAEGSSTSVEDLPGSKPEPDAISVASE 300
Query: 301 AFEDDSCSNFVSEDDSETQSVSSFSSGPTSPSEMPDQFPAVVRPGSLDLPSPVSLSEFGM 360
AFEDDSCSNFVSEDDSETQSVSSFSSGPTSPSEMPDQFPAVVRPGSLDLPSPVSLSEFGM
Sbjct: 301 AFEDDSCSNFVSEDDSETQSVSSFSSGPTSPSEMPDQFPAVVRPGSLDLPSPVSLSEFGM 360
Query: 361 MFPVLGPRSECSGASSPECEVERGDRAEGAENKTSDKANNNRGLSSSSGSGGSSKSQSST 420
MFPVLGPRSECSGASSPECEVERGDRAEGAENKTSDKANNNRGLSSSSGSGGSSKSQSST
Sbjct: 361 MFPVLGPRSECSGASSPECEVERGDRAEGAENKTSDKANNNRGLSSSSGSGGSSKSQSST 420
Query: 421 SPEGQALENRMKQLSLQCSKGRDGIIADIKMVQIG 455
SPEGQALENRMKQLSLQCSKGRDGIIADIKMVQIG
Sbjct: 421 SPEGQALENRMKQLSLQCSKGRDGIIADIKMVQIG 455
>gi|109134344 SH3-domain binding protein 5 (BTK-associated) isoform
b [Homo sapiens]
Length = 298
Score = 584 bits (1505), Expect = e-167
Identities = 298/298 (100%), Positives = 298/298 (100%)
Query: 158 MLNHATQRVMEAEQTKTRSELVHKETAARYNAAMGRMRQLEKKLKRAINKSKPYFELKAK 217
MLNHATQRVMEAEQTKTRSELVHKETAARYNAAMGRMRQLEKKLKRAINKSKPYFELKAK
Sbjct: 1 MLNHATQRVMEAEQTKTRSELVHKETAARYNAAMGRMRQLEKKLKRAINKSKPYFELKAK 60
Query: 218 YYVQLEQLKKTVDDLQAKLTLAKGEYKMALKNLEMISDEIHERRRSSAMGPRGCGVGAEG 277
YYVQLEQLKKTVDDLQAKLTLAKGEYKMALKNLEMISDEIHERRRSSAMGPRGCGVGAEG
Sbjct: 61 YYVQLEQLKKTVDDLQAKLTLAKGEYKMALKNLEMISDEIHERRRSSAMGPRGCGVGAEG 120
Query: 278 SSTSVEDLPGSKPEPDAISVASEAFEDDSCSNFVSEDDSETQSVSSFSSGPTSPSEMPDQ 337
SSTSVEDLPGSKPEPDAISVASEAFEDDSCSNFVSEDDSETQSVSSFSSGPTSPSEMPDQ
Sbjct: 121 SSTSVEDLPGSKPEPDAISVASEAFEDDSCSNFVSEDDSETQSVSSFSSGPTSPSEMPDQ 180
Query: 338 FPAVVRPGSLDLPSPVSLSEFGMMFPVLGPRSECSGASSPECEVERGDRAEGAENKTSDK 397
FPAVVRPGSLDLPSPVSLSEFGMMFPVLGPRSECSGASSPECEVERGDRAEGAENKTSDK
Sbjct: 181 FPAVVRPGSLDLPSPVSLSEFGMMFPVLGPRSECSGASSPECEVERGDRAEGAENKTSDK 240
Query: 398 ANNNRGLSSSSGSGGSSKSQSSTSPEGQALENRMKQLSLQCSKGRDGIIADIKMVQIG 455
ANNNRGLSSSSGSGGSSKSQSSTSPEGQALENRMKQLSLQCSKGRDGIIADIKMVQIG
Sbjct: 241 ANNNRGLSSSSGSGGSSKSQSSTSPEGQALENRMKQLSLQCSKGRDGIIADIKMVQIG 298
Score = 33.5 bits (75), Expect = 0.41
Identities = 26/91 (28%), Positives = 43/91 (47%), Gaps = 10/91 (10%)
Query: 66 LEDARQKFRSVLVE---------ATVKLDELVKKIGKAVEDSKPYWEARRVARQAQLEAQ 116
+E + K RS LV A ++ +L KK+ +A+ SKPY+E + QLE
Sbjct: 10 MEAEQTKTRSELVHKETAARYNAAMGRMRQLEKKLKRAINKSKPYFEL-KAKYYVQLEQL 68
Query: 117 KATQDFQRATEVLRAAKETISLAEQRLLEDD 147
K T D +A L + ++L ++ D+
Sbjct: 69 KKTVDDLQAKLTLAKGEYKMALKNLEMISDE 99
>gi|24308303 SH3-binding domain protein 5-like [Homo sapiens]
Length = 393
Score = 211 bits (538), Expect = 8e-55
Identities = 120/287 (41%), Positives = 175/287 (60%), Gaps = 25/287 (8%)
Query: 37 EEEEVDPRIQGELEKLNQSTDDINRRETELEDARQKFRSVLVEATVKLDELVKKIGKAVE 96
EEEE+DPRIQ ELE LNQ++++IN+ E +L++AR +R +L E+ KL+ +G +E
Sbjct: 52 EEEELDPRIQEELEHLNQASEEINQVELQLDEARTTYRRILQESARKLNTQGSHLGSCIE 111
Query: 97 DSKPYWEARRVARQAQLEAQKATQDFQRATEVLRAAKETISLAEQRLLEDDKRQFDSAWQ 156
++PY+EARR+A++AQ E QKA ++RA + AA+E + +AEQ ++ D K + D WQ
Sbjct: 112 KARPYYEARRLAKEAQQETQKAALRYERAVSMHNAAREMVFVAEQGVMAD-KNRLDPTWQ 170
Query: 157 EMLNHATQRVMEAEQTKTRSELVHKETAARYNAAMGRMRQLEKKLKRAINKSKPYFELKA 216
EMLNHAT +V EAE+ + R E H+ A R++ L+K L+RAI KS+PYFELKA
Sbjct: 171 EMLNHATCKVNEAEEERLRGEREHQRVTRLCQQAEARVQALQKTLRRAIGKSRPYFELKA 230
Query: 217 KYYVQLEQLKKTVDDLQAKLTLAKGEYKMALKNLEMISDEIHERRRSS----AMGP-RGC 271
++ LE+ K V +L+ ++ AK Y +AL+NLE IS++IH RRR +GP R
Sbjct: 231 QFSQILEEHKAKVTELEQQVAQAKTRYSVALRNLEQISEQIHARRRGGLPPHPLGPRRSS 290
Query: 272 GVGAEGSSTSVED-------------------LPGSKPEPDAISVAS 299
VGAE +ED PG P+ D +S+ S
Sbjct: 291 PVGAEAGPEDMEDGDSGIEGAEGAGLEEGSSLGPGPAPDTDTLSLLS 337
Score = 35.0 bits (79), Expect = 0.14
Identities = 28/91 (30%), Positives = 45/91 (49%), Gaps = 8/91 (8%)
Query: 32 EQG-LEEEEEVDPRIQGELEKLNQSTDDINRRETEL---EDARQKFRSVLVEATVKLDEL 87
EQG + ++ +DP Q E LN +T +N E E E Q+ + +A ++ L
Sbjct: 155 EQGVMADKNRLDPTWQ---EMLNHATCKVNEAEEERLRGEREHQRVTRLCQQAEARVQAL 211
Query: 88 VKKIGKAVEDSKPYWEARRVARQAQLEAQKA 118
K + +A+ S+PY+E + Q LE KA
Sbjct: 212 QKTLRRAIGKSRPYFELKAQFSQI-LEEHKA 241
>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
Length = 1976
Score = 62.8 bits (151), Expect = 6e-10
Identities = 62/269 (23%), Positives = 121/269 (44%), Gaps = 24/269 (8%)
Query: 4 ALKRSRSEEPAEILPPARDEEEEEE-------EGMEQGLEEEEEVD---PRIQGELEKLN 53
A ++S S AE A E E+E +E+ LE +EE + +++ ++E L
Sbjct: 1458 AEEKSISARYAEERDRAEAEAREKETKALSLARALEEALEAKEEFERQNKQLRADMEDLM 1517
Query: 54 QSTDDINRRETELEDARQKFRSVLVEATVKLDELVKKIGKAVEDSKPYWEARRVARQAQL 113
S DD+ + ELE +++ + E +L+EL ++ +A ED+K E A +AQ
Sbjct: 1518 SSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDEL-QATEDAKLRLEVNMQAMKAQF 1576
Query: 114 EAQKATQDFQRATEVLRAAKETISLAEQRLLEDDKRQFDSAWQEMLNHATQRVMEAEQTK 173
E T+D Q + K+ L + LED+++ Q L A+++ ME +
Sbjct: 1577 ERDLQTRDEQNEEKKRLLIKQVRELEAE--LEDERK------QRALAVASKKKMEIDLKD 1628
Query: 174 TRSEL-----VHKETAARYNAAMGRMRQLEKKLKRAINKSKPYFELKAKYYVQLEQLKKT 228
+++ E + +M+ +++L+ A F + +L+ L+
Sbjct: 1629 LEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAE 1688
Query: 229 VDDLQAKLTLAKGEYKMALKNLEMISDEI 257
+ LQ +L ++ + A + + ++DEI
Sbjct: 1689 ILQLQEELASSERARRHAEQERDELADEI 1717
Score = 55.5 bits (132), Expect = 1e-07
Identities = 61/271 (22%), Positives = 122/271 (45%), Gaps = 24/271 (8%)
Query: 8 SRSEEPAEILPPARDEEEEEEEGMEQGLEEEEEVDPRIQGELEKLNQSTDDINRRETELE 67
+ +EE L + E EE +E +EEEEE + +Q E +K+ D+ + E E
Sbjct: 904 AEAEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEE 963
Query: 68 DARQKFRSVLVEATVKLDELVKKIGKAVEDSKPYWEARRVA--RQAQLEAQKATQD--FQ 123
ARQK + V A K+ ++ ++I + + + + +++ R A+ +Q A ++ +
Sbjct: 964 GARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAK 1023
Query: 124 RATEVLRAAKETISLAEQRL---------LEDDKRQFDSAWQEMLNHATQRVMEAEQTKT 174
++ + IS E+RL LE KR+ D ++ + + ++A+ +
Sbjct: 1024 NLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAE--LQAQIDEL 1081
Query: 175 RSELVHKETAARYNAAMGRMRQLEKKLKRAINKSKPYFELKAKYYVQLEQLKKTVDDLQA 234
+ +L KE + A G L K N K EL+A Q+ +L++ + +A
Sbjct: 1082 KLQLAKKEEELQGALARGDDETLHKN-----NALKVVRELQA----QIAELQEDFESEKA 1132
Query: 235 KLTLAKGEYKMALKNLEMISDEIHERRRSSA 265
A+ + + + LE + E+ + ++A
Sbjct: 1133 SRNKAEKQKRDLSEELEALKTELEDTLDTTA 1163
Score = 50.4 bits (119), Expect = 3e-06
Identities = 66/305 (21%), Positives = 126/305 (41%), Gaps = 32/305 (10%)
Query: 15 EILPPARDEEEEEEEGMEQGLEEE-------EEVDPRIQGELEKLNQSTDDINRRETELE 67
E L A+ + ++ E + Q LEE+ E+ R+Q EL+ L D + + LE
Sbjct: 1388 ESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRLQQELDDLTVDLDHQRQVASNLE 1447
Query: 68 DARQKFRSVLVEATVKLDELVKKIGKAVEDSKPYWEARRVARQAQLEAQKATQDFQRATE 127
++KF +L E ++ +A +++ +A EA +A ++F+R +
Sbjct: 1448 KKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKALSLARALEEALEAKEEFERQNK 1507
Query: 128 VLRAAKETISLAEQRL------LEDDKRQFDSAWQEM---LNHATQRVMEAEQTKTRSEL 178
LRA E + ++ + LE KR + +EM L + E K R E+
Sbjct: 1508 QLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEV 1567
Query: 179 VHKETAARYNAAMGRMRQLEKKLKRAINKSKPYFELKAKYYVQLEQLKKTVDDLQAKLTL 238
+ A++ + + ++ KR + K Q+ +L+ ++D + + L
Sbjct: 1568 NMQAMKAQFERDLQTRDEQNEEKKRLLIK-------------QVRELEAELEDERKQRAL 1614
Query: 239 A---KGEYKMALKNLEMISDEIHERRRSSAMGPRGCGVGAEGSSTSVEDLPGSKPEPDAI 295
A K + ++ LK+LE + ++ R R + +E+ S+ E A
Sbjct: 1615 AVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQ 1674
Query: 296 SVASE 300
S SE
Sbjct: 1675 SKESE 1679
Score = 48.5 bits (114), Expect = 1e-05
Identities = 54/247 (21%), Positives = 112/247 (45%), Gaps = 29/247 (11%)
Query: 24 EEEEEEGMEQGLEEEEEVDPRIQGELEKLNQSTDDI----------NRRETELEDARQKF 73
+EEE + ++ L + +E +++GELE++ + + + ETEL ++
Sbjct: 850 QEEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAEAEEM 909
Query: 74 RSVLVEATVKLDELVKKIGKAVEDSKPYWEARRVARQAQLEAQKATQDFQRATEVLRAAK 133
R+ L +L+E++ + VE+ + E ++ + + + Q QD + + A+
Sbjct: 910 RARLAAKKQELEEILHDLESRVEEEE---ERNQILQNEKKKMQAHIQDLEEQLDEEEGAR 966
Query: 134 ETISL----AEQRLLEDDKRQFDSAWQEMLNHATQRVMEAEQTKTRSELVHKETAARYNA 189
+ + L AE ++ + ++ Q +++ME + S+L +E A+ N
Sbjct: 967 QKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAK-NL 1025
Query: 190 AMGRMRQ------LEKKLKRAINKSKPYFELKAKYYVQLEQLKKTVDDLQA-----KLTL 238
A R +Q LE++LK+ + + K K + L+ + +LQA KL L
Sbjct: 1026 AKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELKLQL 1085
Query: 239 AKGEYKM 245
AK E ++
Sbjct: 1086 AKKEEEL 1092
Score = 44.7 bits (104), Expect = 2e-04
Identities = 60/264 (22%), Positives = 110/264 (41%), Gaps = 28/264 (10%)
Query: 5 LKRSRSEEPAEILPPARDEEEEEEEGMEQGLEEEEEVDPRIQGELEKLNQSTDDINRRET 64
L+ R +E AE L A +EE + E Q + + R LE+L++ + R +
Sbjct: 1168 LRTKREQEVAE-LKKALEEETKNHEAQIQDMRQ------RHATALEELSEQLEQAKRFKA 1220
Query: 65 ELEDARQKFRSVLVEATVKLDELVKKIGKAVEDSKPYWEARRVARQAQLEAQKATQDFQR 124
LE +Q + E ++ K+ + V+ + + A+ +L A+ + D R
Sbjct: 1221 NLEKNKQGLETDNKELACEV-----KVLQQVKAESEHKRKKLDAQVQELHAKVSEGDRLR 1275
Query: 125 ATEVLRAAKETISLAEQRLLEDDKRQFDSAWQEMLNHATQRVMEAEQTKTRSELVHKETA 184
+A+K Q L++ + A ++ + A Q + EL+ +ET
Sbjct: 1276 VELAEKASK------LQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETR 1329
Query: 185 ARYNAAMGRMRQLEKKLKRAINKSKPYFELKAK--------YYVQLEQLKKTVDDLQAKL 236
+ N + R+RQLE++ K ++ + + E K QL KK VDD +
Sbjct: 1330 QKLNLS-SRIRQLEEE-KNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDDLGTI 1387
Query: 237 TLAKGEYKMALKNLEMISDEIHER 260
+ K LK+ E +S + E+
Sbjct: 1388 ESLEEAKKKLLKDAEALSQRLEEK 1411
Score = 37.4 bits (85), Expect = 0.028
Identities = 55/272 (20%), Positives = 113/272 (41%), Gaps = 35/272 (12%)
Query: 11 EEPAEILPPARDEEEEEEEGMEQGLEEEEEVDPRIQGELEKLNQSTDDINRRETELEDAR 70
+E + L + + ++ + +E+ +E+ + + +KL +I + + EL +
Sbjct: 1641 DEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSE 1700
Query: 71 QKFRSVLVEATVKLDELVKKIG--KAVEDSKPYWEARRVARQAQLEAQKATQD-----FQ 123
+ R E DE+ A+ D K EAR + +LE +++ + F+
Sbjct: 1701 RARRHAEQERDELADEITNSASGKSALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFR 1760
Query: 124 RATEVL----------RAAKETISLAEQRLLEDDKRQFDSAWQEMLN------HATQRVM 167
+ T + R+A + A Q+L E ++ + QE+ AT +
Sbjct: 1761 KTTLQVDTLNAELAAERSAAQKSDNARQQL-ERQNKELKAKLQELEGAVKSKFKATISAL 1819
Query: 168 EAEQTKTRSELVHKETAARYNAAMGRM-RQLEKKLKRAI-------NKSKPYFELKAKYY 219
EA+ + +L E A+ AA ++ R+ EKKLK + Y E K
Sbjct: 1820 EAKIGQLEEQL---EQEAKERAAANKLVRRTEKKLKEIFMQVEDERRHADQYKEQMEKAN 1876
Query: 220 VQLEQLKKTVDDLQAKLTLAKGEYKMALKNLE 251
+++QLK+ +++ + + T A + + L+
Sbjct: 1877 ARMKQLKRQLEEAEEEATRANASRRKLQRELD 1908
Score = 37.0 bits (84), Expect = 0.037
Identities = 39/238 (16%), Positives = 101/238 (42%), Gaps = 7/238 (2%)
Query: 25 EEEEEGMEQGLEEEEEVDPRIQGELEKLNQSTDDINRRETELEDARQKFRSVLVEATVKL 84
E + + ++ L+EE + + +L + + + ++ E E+AR+ ++ +L
Sbjct: 1314 ESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQL 1373
Query: 85 DELVKKIGKAVEDSKPYWEARRVARQAQLEAQKATQDFQRATEVLRAAKETISLAEQRLL 144
+ KK+ + + EA+ ++ +A+ +Q + ++T + +Q L
Sbjct: 1374 ADTKKKVDDDLGTIESLEEAK---KKLLKDAEALSQRLEEKALAYDKLEKTKNRLQQEL- 1429
Query: 145 EDDKRQFDSAWQEMLNHATQRVMEAEQTKTRSELVHKETAARYNAAMGRMRQLEKKLKRA 204
DD +++ ++ ++ + +Q + + A + A R+ E K
Sbjct: 1430 -DDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKALSL 1488
Query: 205 INKSKPYFELKAKYYVQLEQLKKTVDDL-QAKLTLAKGEYKMALKNLEMISDEIHERR 261
+ E K ++ Q +QL+ ++DL +K + K +++ K+ + ++ E R
Sbjct: 1489 ARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELE-KSKRALEQQVEEMR 1545
Score = 35.0 bits (79), Expect = 0.14
Identities = 57/257 (22%), Positives = 109/257 (42%), Gaps = 32/257 (12%)
Query: 2 DAALKRSRSEEPAEILPPARDEE----------EEEEEGMEQGLEEEEEVDPRIQGELEK 51
DAA S+ ++ E+L ++ EEE+ +++ EEEEE ++ ++
Sbjct: 1309 DAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLA 1368
Query: 52 LNQSTDDINRRETE-------LEDARQKFRSVLVEATVKLDE---LVKKIGKAVEDSKPY 101
L D ++ + LE+A++K + +L+E K+ K +
Sbjct: 1369 LQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRLQQE 1428
Query: 102 WEARRVARQAQLEAQKATQDFQRATEVLRAAKETIS--LAEQRLLEDDKRQFDSAWQEML 159
+ V Q + + Q+ + L A +++IS AE+R D+ + ++ +E
Sbjct: 1429 LDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEER----DRAEAEAREKETK 1484
Query: 160 NHATQRVM-EAEQTKTRSELVHKETAARYNAAMGRMRQLEKKLKRAINKSKPYFELKA-K 217
+ R + EA + K E +K+ A M + K + + KSK E + +
Sbjct: 1485 ALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNV-HELEKSKRALEQQVEE 1543
Query: 218 YYVQLEQLKKTVDDLQA 234
QLE+L+ D+LQA
Sbjct: 1544 MRTQLEELE---DELQA 1557
>gi|114155140 tropomyosin 3 isoform 1 [Homo sapiens]
Length = 285
Score = 56.6 bits (135), Expect = 5e-08
Identities = 59/258 (22%), Positives = 114/258 (44%), Gaps = 26/258 (10%)
Query: 20 ARDEEEEEEEGMEQGLEEEEEVDPRIQGELEKLNQSTDDINRRETELEDARQKFRSV--- 76
A D E+ E +Q E ++++ + +KL + D++++ L+DA++K
Sbjct: 19 ALDRAEQAEAEQKQAEERSKQLEDELAAMQKKLKGTEDELDKYSEALKDAQEKLELAEKK 78
Query: 77 LVEATVKLDELVKKIGKAVEDSKPYWEARRVARQAQLEAQKATQDFQRATEVL--RAAK- 133
+A ++ L ++I E+ E A Q EA+KA + +R +V+ RA K
Sbjct: 79 AADAEAEVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIENRALKD 138
Query: 134 -ETISLAEQRLLEDDK--RQFDSAWQEMLNHATQRVMEAEQTKTRSELVHK---ETAARY 187
E + L E +L E + D ++E+ + E+T+ R+EL E
Sbjct: 139 EEKMELQEIQLKEAKHIAEEADRKYEEVARKLVIIEGDLERTEERAELAESKCSELEEEL 198
Query: 188 NAAMGRMRQLEKKLKRAINKSKPY-------------FELKAKYYVQ-LEQLKKTVDDLQ 233
++ LE + ++ K Y E +A++ + + +L+KT+DDL+
Sbjct: 199 KNVTNNLKSLEAQAEKYSQKEDKYEEEIKILTDKLKEAETRAEFAERSVAKLEKTIDDLE 258
Query: 234 AKLTLAKGEYKMALKNLE 251
+L K +YK + L+
Sbjct: 259 DELYAQKLKYKAISEELD 276
>gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo
sapiens]
Length = 1939
Score = 56.2 bits (134), Expect = 6e-08
Identities = 64/255 (25%), Positives = 109/255 (42%), Gaps = 22/255 (8%)
Query: 5 LKRSRSEE--PAEILPPARDEEEEEEEGMEQGLEEEEEVDPRIQGELEKLNQSTDDINRR 62
LKR EE L A + + + + EEE+E +Q + K N
Sbjct: 1319 LKRQLEEEIKAKSALAHALQSSRHDCDLLREQYEEEQEAKAELQRAMSKAN--------- 1369
Query: 63 ETELEDARQKFRSVLVEATVKLDELVKKIGKAVEDSKPYWEARRVARQAQLEAQKATQDF 122
+E+ R K+ + ++ T +L+E KK+ + ++D++ + EA A+ A LE K Q
Sbjct: 1370 -SEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVN-AKCASLE--KTKQRL 1425
Query: 123 QRATEVLRAAKETISLAEQRLLEDDKRQFDSAWQEMLNHATQRVMEAEQTKTRSELVHKE 182
Q E L E + A L+ +R FD E + E E ++ S + E
Sbjct: 1426 QNEVEDLMIDVERTN-AACAALDKKQRNFDKILAEWKQKCEETHAELEASQKESRSLSTE 1484
Query: 183 TAARYNAAMGRMRQLE------KKLKRAINKSKPYFELKAKYYVQLEQLKKTVDDLQAKL 236
NA + QLE K L++ I+ K +LE++KK V+ +++L
Sbjct: 1485 LFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKSEL 1544
Query: 237 TLAKGEYKMALKNLE 251
A E + +L++ E
Sbjct: 1545 QAALEEAEASLEHEE 1559
Score = 43.5 bits (101), Expect = 4e-04
Identities = 56/262 (21%), Positives = 112/262 (42%), Gaps = 22/262 (8%)
Query: 11 EEPAEILPPARDEEEEEEEGMEQGLEEEEEVDPRIQGELEKLNQSTDDINRRETELEDAR 70
E+ L E + +EE ++ + + R+Q E + ++ D+ + ++L +
Sbjct: 1250 EKMCRALEDQLSEIKTKEEEQQRLINDLTAQRARLQTESGEYSRQLDEKDTLVSQLSRGK 1309
Query: 71 QKFRSVLVEATVKLDELVK---KIGKAVEDSKPYWEARRVARQAQLEAQKATQDFQRA-- 125
Q F + E +L+E +K + A++ S+ + + R+ E Q+A + QRA
Sbjct: 1310 QAFTQQIEELKRQLEEEIKAKSALAHALQSSRHDCD---LLREQYEEEQEAKAELQRAMS 1366
Query: 126 ---TEVL--RAAKETISLAEQRLLEDDKRQFDSAWQEMLNH---ATQRVMEAEQTKTRSE 177
+EV R ET ++ LE+ K++ Q+ H + E+TK R +
Sbjct: 1367 KANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNAKCASLEKTKQRLQ 1426
Query: 178 LVHKE---TAARYNAAMGRMRQLEKKLKRAINKSKPYFELKAKYYVQLEQLKKTVDDLQA 234
++ R NAA + + ++ + + + K E + + +LE +K L
Sbjct: 1427 NEVEDLMIDVERTNAACAALDKKQRNFDKILAEWKQKCE---ETHAELEASQKESRSLST 1483
Query: 235 KLTLAKGEYKMALKNLEMISDE 256
+L K Y+ +L LE + E
Sbjct: 1484 ELFKIKNAYEESLDQLETLKRE 1505
Score = 40.8 bits (94), Expect = 0.003
Identities = 51/271 (18%), Positives = 118/271 (43%), Gaps = 40/271 (14%)
Query: 10 SEEPAEILPPARDEEEEEEEGMEQGLEEEEEVDP-------RIQGELEKLNQSTDDINRR 62
+EE + L + + E + + + + E+EEE++ +++ E +L + DD+
Sbjct: 905 AEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELT 964
Query: 63 ETELEDARQKFRSVLVEATVKLDELVKKIGKAVEDSKPYWEARR--------------VA 108
++E + + + T ++ L + I K ++ K EA +
Sbjct: 965 LAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTL 1024
Query: 109 RQAQLEAQKATQDFQRATEVLRAAKETISLAEQRLLEDDKRQFDSAWQEMLNHATQRVME 168
+A+++ ++ D + + E + + + A +R LE D + + ++ N Q ++
Sbjct: 1025 TKAKIKLEQQVDDLEGSLEQEKKIRMDLERA-KRKLEGDLKLAQESTMDIENDKQQ--LD 1081
Query: 169 AEQTKTRSELVHKETAARYNAAMGRMRQLEKKLKRAINKSKPYFELKAKYYVQLEQLKKT 228
+ K E+ ++ A+G QL+KK+K EL+A+ +E+L++
Sbjct: 1082 EKLKKKEFEMSGLQSKIEDEQALG--MQLQKKIK----------ELQAR----IEELEEE 1125
Query: 229 VDDLQAKLTLAKGEYKMALKNLEMISDEIHE 259
++ +A A+ + + LE IS+ + E
Sbjct: 1126 IEAERASRAKAEKQRSDLSRELEEISERLEE 1156
Score = 39.7 bits (91), Expect = 0.006
Identities = 50/243 (20%), Positives = 93/243 (38%), Gaps = 27/243 (11%)
Query: 2 DAALKRSRSEEPAEILPPARDEEEEEEEGMEQGLEEEEEVDPRIQGELEKLNQSTDDINR 61
DA + EE + L + EE E + E+ R+Q E+E L + N
Sbjct: 1382 DAIQRTEELEEAKKKLAQRLQDAEEHVEAVNAKCASLEKTKQRLQNEVEDLMIDVERTNA 1441
Query: 62 RETELEDARQKFRSVLVEATVKLDELVKKIGKAVEDSKPYWEARRVARQAQLEAQKATQD 121
L+ ++ F +L E K +E ++ + ++S R E K
Sbjct: 1442 ACAALDKKQRNFDKILAEWKQKCEETHAELEASQKES----------RSLSTELFKIKNA 1491
Query: 122 FQRATEVLRAAKETISLAEQRLLEDDKRQFDSAWQEMLNHATQRVMEAEQTKTRSELVHK 181
++ + + L K +Q + S E + +R+ E E+ K + E
Sbjct: 1492 YEESLDQLETLKRENKNLQQEI---------SDLTEQIAEGGKRIHELEKIKKQVEQEKS 1542
Query: 182 ETAARYNAAMGRMRQLEKKLKR---AINKSKPYFELK-AKYYVQLEQLKKT----VDDLQ 233
E A A + E K+ R +N+ K + K A+ +++Q+K+ V+ +Q
Sbjct: 1543 ELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQMKRNHIRIVESMQ 1602
Query: 234 AKL 236
+ L
Sbjct: 1603 STL 1605
Score = 37.0 bits (84), Expect = 0.037
Identities = 46/269 (17%), Positives = 115/269 (42%), Gaps = 35/269 (13%)
Query: 1 MDAALKRSRS------------EEPAEILPPARDEEEEEEEGMEQGLEEEEEVDPRIQGE 48
++A+ K SRS EE + L + E + ++ + E+ E RI E
Sbjct: 1471 LEASQKESRSLSTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIH-E 1529
Query: 49 LEKLN----QSTDDINRRETELEDARQKFRSVLVEATVKLDELVKKIGKAVEDSKPYWEA 104
LEK+ Q ++ E E + + ++ ++L+++ ++ + + + +
Sbjct: 1530 LEKIKKQVEQEKSELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQ 1589
Query: 105 RRVARQAQLEAQKATQDFQRATEVLRAAKETISLAEQRLLEDDKRQFDSAWQEMLNHATQ 164
+ +E+ ++T D + +R+ + I L ++ +E D + + LNHA +
Sbjct: 1590 MKRNHIRIVESMQSTLDAE-----IRSRNDAIRLKKK--MEGDLNEMEI----QLNHANR 1638
Query: 165 RVMEAEQTKTRSELVHKETAARYNAAMGRMRQLEKKLKRAINKSKPYFELKAKYYVQLEQ 224
EA + ++ + K+T + A+ L+++L ++ ++E+
Sbjct: 1639 MAAEALRNYRNTQAILKDTQLHLDDALRSQEDLKEQLAMVERRAN-------LLQAEIEE 1691
Query: 225 LKKTVDDLQAKLTLAKGEYKMALKNLEMI 253
L+ T++ + +A+ E A + ++++
Sbjct: 1692 LRATLEQTERSRKIAEQELLDASERVQLL 1720
Score = 36.2 bits (82), Expect = 0.063
Identities = 63/292 (21%), Positives = 127/292 (43%), Gaps = 37/292 (12%)
Query: 2 DAALKRSRSEEPAEILPPARDEEEEEEEGMEQGLEEEEEVDPRIQGELEKL---NQSTDD 58
+ A + E+ E L + +E EE M ++E+ ++ ++Q E + L + D
Sbjct: 852 EMANMKEEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADSLADAEERCDQ 911
Query: 59 INRRETELE----------DARQKFRSVLVEATVKLDELVKKIGKAVEDSKPYWEARRVA 108
+ + + +LE + ++ + L KL++ ++ K ++D +
Sbjct: 912 LIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLE--------L 963
Query: 109 RQAQLEAQK-ATQD-FQRATEVLRAAKETIS--LAEQRLLEDDKRQ-FDS--AWQEMLNH 161
A++E +K AT++ + TE + ETI+ E++ L++ +Q D A ++ +N
Sbjct: 964 TLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNT 1023
Query: 162 ATQRVMEAEQTKTRSE-LVHKETAARYNAAMGRMRQLEKKLKRA------INKSKPYFEL 214
T+ ++ EQ E + +E R + + R+LE LK A I K +
Sbjct: 1024 LTKAKIKLEQQVDDLEGSLEQEKKIRMDLERAK-RKLEGDLKLAQESTMDIENDKQQLDE 1082
Query: 215 KAKYY-VQLEQLKKTVDDLQAKLTLAKGEYKMALKNLEMISDEIHERRRSSA 265
K K ++ L+ ++D QA + + K +E + +EI R S A
Sbjct: 1083 KLKKKEFEMSGLQSKIEDEQALGMQLQKKIKELQARIEELEEEIEAERASRA 1134
>gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo
sapiens]
Length = 1939
Score = 55.1 bits (131), Expect = 1e-07
Identities = 66/258 (25%), Positives = 119/258 (46%), Gaps = 28/258 (10%)
Query: 5 LKRSRSEEPA--EILPPARDEEEEEEEGMEQGLEEEEEVDPRIQGELEKLNQSTDDINRR 62
LKR EE L A + + + + EEE+E +Q + K N
Sbjct: 1319 LKRQLEEETKAKSTLAHALQSARHDCDLLREQYEEEQEAKAELQRGMSKAN--------- 1369
Query: 63 ETELEDARQKFRSVLVEATVKLDELVKKIGKAVEDSKPYWEARRVARQAQLEAQKATQDF 122
+E+ R K+ + ++ T +L+E KK+ + ++D++ + EA ++ A LE K Q
Sbjct: 1370 -SEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVN-SKCASLE--KTKQRL 1425
Query: 123 QRATEVLRAAKETISLAEQRLLEDDKRQFD---SAWQEMLNHATQRVMEAEQTKTRS--- 176
Q E L E S A L+ +R FD + W++ TQ +EA Q ++RS
Sbjct: 1426 QNEVEDLMIDVER-SNAACIALDKKQRNFDKVLAEWKQKYEE-TQAELEASQKESRSLST 1483
Query: 177 ELVHKETAARYNAAMGRMRQLE---KKLKRAINKSKPYFELKAKYYVQLEQLKKTVDDLQ 233
EL + A Y ++ + L+ K L++ I+ K+ +LE++KK +D +
Sbjct: 1484 ELFKVKNA--YEESLDHLETLKRENKNLQQEISDLTEQIAEGGKHIHELEKVKKQLDHEK 1541
Query: 234 AKLTLAKGEYKMALKNLE 251
++L + E + +L++ E
Sbjct: 1542 SELQTSLEEAEASLEHEE 1559
Score = 43.9 bits (102), Expect = 3e-04
Identities = 46/265 (17%), Positives = 109/265 (41%), Gaps = 36/265 (13%)
Query: 1 MDAALKRSRSEEPAEILPPARDEEEEEEEGMEQGLEEEEEVDPRIQGELEKLNQSTDDIN 60
MD + + E ++ + + E +++ + + L+++E +QG++E
Sbjct: 1050 MDLERAKRKLEGDLKLAQESTMDTENDKQQLNEKLKKKEFEMSNLQGKIED--------- 1100
Query: 61 RRETELEDARQKFRSVLVEATVKLDELVKKIGKAVEDSKPYWEARRVARQAQLEAQKATQ 120
E A ++L + +K++ +E+ + EA R +R +A+K
Sbjct: 1101 ------EQA----------LAIQLQKKIKELQARIEELEEEIEAERASR---AKAEKQRS 1141
Query: 121 DFQRATEVLRAAKETISLAEQRLLEDDKRQFDSAWQEMLNHATQRVMEAEQTKTRSELVH 180
D R E + E A +E +K++ ++ +Q+M + ++ E T H
Sbjct: 1142 DLSRELEEISERLEEAGGATSAQIEMNKKR-EAEFQKMRRDLEESTLQHEATAAALRKKH 1200
Query: 181 KETAARYNAAMGRMRQLEKK-------LKRAINKSKPYFELKAKYYVQLEQLKKTVDDLQ 233
++ A + ++++++K LK IN E +K E++ +T++D
Sbjct: 1201 ADSVAELGEQIDSLQRVKQKLEKEKSELKMEINDLASNMETVSKAKANFEKMCRTLEDQL 1260
Query: 234 AKLTLAKGEYKMALKNLEMISDEIH 258
+++ + E + + L +H
Sbjct: 1261 SEIKTKEEEQQRLINELSAQKARLH 1285
Score = 42.0 bits (97), Expect = 0.001
Identities = 51/259 (19%), Positives = 113/259 (43%), Gaps = 16/259 (6%)
Query: 10 SEEPAEILPPARDEEEEEEEGMEQGLEEEEEVDP-------RIQGELEKLNQSTDDINRR 62
+EE + L + + E + + + + E+EEE++ +++ E +L + DD+
Sbjct: 905 AEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELT 964
Query: 63 ETELEDARQKFRSVLVEATVKLDELVKKIGKAVEDSKPYWEA-RRVARQAQLEAQKATQD 121
++E + + + T ++ L + I K ++ K EA ++ Q+E K
Sbjct: 965 LAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQMEEDKVNTL 1024
Query: 122 FQRATEVLRAAKETI-SLAEQRLLEDDKRQFDSAWQEMLNHATQRVMEAEQTKTRSELVH 180
+ T++ + + SL +++ L D + + L A + M+ E K +
Sbjct: 1025 TKAKTKLEQQVDDLEGSLEQEKKLCMDLERAKRKLEGDLKLAQESTMDTENDKQQLNEKL 1084
Query: 181 KETAARYNAAMGRMRQLEKKLKRAINKSKPYFELKAKYYVQLEQLKKTVDDLQAKLTLAK 240
K+ + G+ +E + AI K EL+A+ +E+L++ ++ +A A+
Sbjct: 1085 KKKEFEMSNLQGK---IEDEQALAIQLQKKIKELQAR----IEELEEEIEAERASRAKAE 1137
Query: 241 GEYKMALKNLEMISDEIHE 259
+ + LE IS+ + E
Sbjct: 1138 KQRSDLSRELEEISERLEE 1156
Score = 38.1 bits (87), Expect = 0.017
Identities = 49/238 (20%), Positives = 93/238 (39%), Gaps = 22/238 (9%)
Query: 2 DAALKRSRSEEPAEILPPARDEEEEEEEGMEQGLEEEEEVDPRIQGELEKLNQSTDDINR 61
DA + EE + L + EE E + E+ R+Q E+E L + N
Sbjct: 1382 DAIQRTEELEEAKKKLAQRLQDAEEHVEAVNSKCASLEKTKQRLQNEVEDLMIDVERSNA 1441
Query: 62 RETELEDARQKFRSVLVEATVKLDELVKKIGKAVEDSKPYWEARRVARQAQLEAQKATQD 121
L+ ++ F VL E K +E ++ + ++S+ + A E+ +
Sbjct: 1442 ACIALDKKQRNFDKVLAEWKQKYEETQAELEASQKESRSLSTELFKVKNAYEESLDHLET 1501
Query: 122 FQRATEVLRAAKETISLAEQ--------RLLEDDKRQFDSAWQEMLNHATQRVMEAEQTK 173
+R + L+ +E L EQ LE K+Q D E ++ +
Sbjct: 1502 LKRENKNLQ--QEISDLTEQIAEGGKHIHELEKVKKQLDHEKSE---------LQTSLEE 1550
Query: 174 TRSELVHKETAARYNAAMGRMRQLEKKLKRAI-NKSKPYFELKAKYYVQLEQLKKTVD 230
+ L H+E + + Q++ ++ R I K + +LK + +E ++ T+D
Sbjct: 1551 AEASLEHEE--GKILRIQLELNQVKSEIDRKIAEKDEELDQLKRNHLRVVESMQSTLD 1606
Score = 36.6 bits (83), Expect = 0.048
Identities = 49/219 (22%), Positives = 90/219 (41%), Gaps = 30/219 (13%)
Query: 41 VDPRIQGELEKLNQSTDDINRRETELEDARQKFRSVLVEATVKLDELVKKIGKAVEDSKP 100
+ +++G+L ++ + NR+ E + + +L + + LD+ + + +D K
Sbjct: 1618 IKKKMEGDLNEMEIQLNHANRQAAEALRNLRNTQGILKDTQLHLDDAI----RGQDDLKE 1673
Query: 101 YWEARRVARQAQLEAQKATQDFQRATEVLRAAKETISLAEQRLLEDDKRQFDSAWQEMLN 160
+ V R+A L Q E LRA+ LE +R A QE+L+
Sbjct: 1674 --QLAMVERRANL--------MQAEVEELRAS-----------LERTERGRKMAEQELLD 1712
Query: 161 HATQRVMEAEQTKTRSELVHKETAARYNAAMGRMRQLEKKLKRAINKSKPYFELKAKYYV 220
A++RV T K+ + G M + ++ + A K+K A +
Sbjct: 1713 -ASERVQLLHTQNTSLINTKKKLETDISQIQGEMEDIVQEARNAEEKAKKAITDAA---M 1768
Query: 221 QLEQLKKTVDDLQAKLTLAKGEYKMALKNLEMISDEIHE 259
E+LKK D A L K + +K+L++ DE +
Sbjct: 1769 MAEELKKE-QDTSAHLERMKKNMEQTVKDLQLRLDEAEQ 1806
>gi|93102364 SWAP-70 protein [Homo sapiens]
Length = 585
Score = 54.7 bits (130), Expect = 2e-07
Identities = 54/220 (24%), Positives = 103/220 (46%), Gaps = 20/220 (9%)
Query: 21 RDEEEEEEEGMEQGLEEEEEVDPRIQGELEKLNQSTDDINRRETELEDAR--------QK 72
R ++ E+E +E+ ++E + + Q ELE + + ++ R E E R +
Sbjct: 327 RKKQLAEQEELERQMKELQAANESKQQELEAVRKKLEEAASRAAEEEKKRLQTQVELQAR 386
Query: 73 FRSVLVEATVKLDELVKKIGKAVEDSKPYWEARRVARQAQLEAQKATQDFQRATEVLRAA 132
F + L + ++ +++ + + + Y + R L+ Q+A +D ++A R
Sbjct: 387 FSTELEREKLIRQQMEEQVAQKSSELEQYLQRVRELEDMYLKLQEALEDERQA----RQD 442
Query: 133 KETISLAEQRLLEDD--KRQFDSAWQEMLNHATQRVMEAEQTKTRSELVHKETAARYNAA 190
+ET+ + RLLE++ KR W A Q EAE+ + ++ V KE A + A
Sbjct: 443 EETVRKLQARLLEEESSKRAELEKWHLEQQQAIQ-TTEAEKQELENQRVLKEQALQ--EA 499
Query: 191 MGRMRQLEKKLKRAINKSKPYFELKAKYYVQLEQLKKTVD 230
M ++ QLE + K+A+ + Y E+K K + + K D
Sbjct: 500 MEQLEQLELERKQALEQ---YEEVKKKLEMATNKTKSWKD 536
Score = 36.6 bits (83), Expect = 0.048
Identities = 50/244 (20%), Positives = 106/244 (43%), Gaps = 53/244 (21%)
Query: 18 PPARDEEEEEEEGMEQGLEEEEEVDPRIQGELEKLNQSTDDINRRETELEDARQKFRSVL 77
PP ++ + +E ++ L E+EE++ +++ EL+ N+S ++ ELE R+K
Sbjct: 314 PPHKEARQRRKELRKKQLAEQEELERQMK-ELQAANES------KQQELEAVRKK----- 361
Query: 78 VEATVKLDELVKKIGKAVEDSKPYWEARRVARQAQLEAQKATQDFQRATEVLRAAKETIS 137
L + +A E+ K +R+ Q +L+A+ +T+
Sbjct: 362 ---------LEEAASRAAEEEK-----KRLQTQVELQARFSTE----------------- 390
Query: 138 LAEQRLLEDDKRQFDSAWQEMLNHATQRVMEAEQTKTR-SELVHKETAARYNAAMGRMRQ 196
L ++L+ + + L QRV E E + E + E AR + +R+
Sbjct: 391 LEREKLIRQQMEEQVAQKSSELEQYLQRVRELEDMYLKLQEALEDERQARQDEE--TVRK 448
Query: 197 LEKKLKRAINKSKPYFELKAKYYVQLEQLKKTVD----DLQAKLTLAKGEYKMALKNLEM 252
L+ +L + + E K++++ +Q +T + +L+ + L + + A++ LE
Sbjct: 449 LQARLLEEESSKRAELE---KWHLEQQQAIQTTEAEKQELENQRVLKEQALQEAMEQLEQ 505
Query: 253 ISDE 256
+ E
Sbjct: 506 LELE 509
>gi|115511012 coiled-coil domain containing 136 [Homo sapiens]
Length = 1154
Score = 54.7 bits (130), Expect = 2e-07
Identities = 64/251 (25%), Positives = 115/251 (45%), Gaps = 31/251 (12%)
Query: 15 EILPPARDEEEEEEEGMEQGLEEEEEVDPRIQGELEKLNQSTD-DINRRETELEDARQKF 73
E+L PA EEEEEEE E+ +EEEEE + G + L+ + ++ ETELE+
Sbjct: 7 EVLLPALYEEEEEEEEEEEEVEEEEE-QVQKGGSVGSLSVNKHRGLSLTETELEE----L 61
Query: 74 RSVLVEATVKLDELVKKIGKAVEDS---KPYWEARRVARQAQLEAQKATQDFQRATEVLR 130
R+ +++ +L+E + G+ +DS + E R+A Q A+ T+ Q+ LR
Sbjct: 62 RAQVLQLVAELEETRELAGQHEDDSLELQGLLEDERLASAQQ--AEVFTKQIQQLQGELR 119
Query: 131 AAKETISLAEQRLLEDDKRQFDSAWQEMLNHATQRVMEAEQTKTRSELVHKETAARYNAA 190
+ +E IS LLE +K ++ L+ A + Q S H+ A
Sbjct: 120 SLREEIS-----LLEHEKESELKEIEQELHLAQAEIQSLRQAAEDSATEHESDIA----- 169
Query: 191 MGRMRQLEKKLKRAINKSKPYFELKAKYYVQLEQLKKTVDDLQAKLTLAKGEYKMALKNL 250
L++ L R N+ + ++ Y +++ L+ +++ K + G + L +
Sbjct: 170 -----SLQEDLCRMQNELEDMERIRGDYEMEIASLRA---EMEMKSSEPSG--SLGLSDY 219
Query: 251 EMISDEIHERR 261
+ +E+ E R
Sbjct: 220 SGLQEELQELR 230
>gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 53.1 bits (126), Expect = 5e-07
Identities = 67/258 (25%), Positives = 115/258 (44%), Gaps = 28/258 (10%)
Query: 5 LKRSRSEE--PAEILPPARDEEEEEEEGMEQGLEEEEEVDPRIQGELEKLNQSTDDINRR 62
LKR EE L A + + + + EEE+E +Q L K N
Sbjct: 1321 LKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKAN--------- 1371
Query: 63 ETELEDARQKFRSVLVEATVKLDELVKKIGKAVEDSKPYWEARRVARQAQLEAQKATQDF 122
TE+ R K+ + ++ T +L+E KK+ + ++ ++ + EA A+ A LE K Q
Sbjct: 1372 -TEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVN-AKCASLE--KTKQRL 1427
Query: 123 QRATEVLRAAKETISLAEQRLLEDDKRQFD---SAWQEMLNHATQRVMEAEQTKTRS--- 176
Q E L E + A L+ +R FD + W++ T +EA Q + RS
Sbjct: 1428 QNEVEDLMLDVERTN-AACAALDKKQRNFDKILAEWKQKCEE-THAELEASQKEARSLGT 1485
Query: 177 ELVHKETAARYNAAMGRMRQLE---KKLKRAINKSKPYFELKAKYYVQLEQLKKTVDDLQ 233
EL + A Y ++ ++ L+ K L++ I+ K +LE++KK V+ +
Sbjct: 1486 ELFKIKNA--YEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEK 1543
Query: 234 AKLTLAKGEYKMALKNLE 251
+L A E + +L++ E
Sbjct: 1544 CELQAALEEAEASLEHEE 1561
Score = 42.7 bits (99), Expect = 7e-04
Identities = 56/262 (21%), Positives = 112/262 (42%), Gaps = 22/262 (8%)
Query: 11 EEPAEILPPARDEEEEEEEGMEQGLEEEEEVDPRIQGELEKLNQSTDDINRRETELEDAR 70
E+ L E + +EE ++ + + R+Q E + ++ D+ ++L +
Sbjct: 1252 EKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGK 1311
Query: 71 QKFRSVLVEATVKLDELVK---KIGKAVEDSKPYWEARRVARQAQLEAQKATQDFQRA-- 125
Q F + E +L+E +K + A++ S+ + + R+ E Q++ + QRA
Sbjct: 1312 QAFTQQIEELKRQLEEEIKAKNALAHALQSSRHDCD---LLREQYEEEQESKAELQRALS 1368
Query: 126 ---TEVL--RAAKETISLAEQRLLEDDKRQFD---SAWQEMLNHATQRVMEAEQTKTRSE 177
TEV R ET ++ LE+ K++ A +E + + E+TK R +
Sbjct: 1369 KANTEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQ 1428
Query: 178 LVHKE---TAARYNAAMGRMRQLEKKLKRAINKSKPYFELKAKYYVQLEQLKKTVDDLQA 234
++ R NAA + + ++ + + + K E + + +LE +K L
Sbjct: 1429 NEVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQKCE---ETHAELEASQKEARSLGT 1485
Query: 235 KLTLAKGEYKMALKNLEMISDE 256
+L K Y+ +L LE + E
Sbjct: 1486 ELFKIKNAYEESLDQLETLKRE 1507
Score = 41.2 bits (95), Expect = 0.002
Identities = 51/271 (18%), Positives = 119/271 (43%), Gaps = 40/271 (14%)
Query: 10 SEEPAEILPPARDEEEEEEEGMEQGLEEEEEVDP-------RIQGELEKLNQSTDDINRR 62
+EE + L + + E + + + + E+EEE++ +++ E +L + DD+
Sbjct: 907 AEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELT 966
Query: 63 ETELEDARQKFRSVLVEATVKLDELVKKIGKAVEDSKPYWEARR--------------VA 108
++E + + + T ++ L + I K ++ K EA +
Sbjct: 967 LAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTL 1026
Query: 109 RQAQLEAQKATQDFQRATEVLRAAKETISLAEQRLLEDDKRQFDSAWQEMLNHATQRVME 168
+A+++ ++ D + + E + + + A +R LE D + + ++ N Q ++
Sbjct: 1027 TKAKIKLEQQVDDLEGSLEQEKKLRMDLERA-KRKLEGDLKLAQESIMDIENEKQQ--LD 1083
Query: 169 AEQTKTRSELVHKETAARYNAAMGRMRQLEKKLKRAINKSKPYFELKAKYYVQLEQLKKT 228
+ K E+ + ++ A+G QL+KK+K EL+A+ +E+L++
Sbjct: 1084 EKLKKKEFEISNLQSKIEDEQALG--IQLQKKIK----------ELQAR----IEELEEE 1127
Query: 229 VDDLQAKLTLAKGEYKMALKNLEMISDEIHE 259
++ +A A+ + + LE IS+ + E
Sbjct: 1128 IEAERASRAKAEKQRSDLSRELEEISERLEE 1158
Score = 37.7 bits (86), Expect = 0.022
Identities = 51/243 (20%), Positives = 92/243 (37%), Gaps = 27/243 (11%)
Query: 2 DAALKRSRSEEPAEILPPARDEEEEEEEGMEQGLEEEEEVDPRIQGELEKLNQSTDDINR 61
DA + EE + L EE E + E+ R+Q E+E L + N
Sbjct: 1384 DAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNA 1443
Query: 62 RETELEDARQKFRSVLVEATVKLDELVKKIGKAVEDSKPYWEARRVARQAQLEAQKATQD 121
L+ ++ F +L E K +E ++ +++ AR E K
Sbjct: 1444 ACAALDKKQRNFDKILAEWKQKCEETHAELE----------ASQKEARSLGTELFKIKNA 1493
Query: 122 FQRATEVLRAAKETISLAEQRLLEDDKRQFDSAWQEMLNHATQRVMEAEQTKTRSELVHK 181
++ + + L K +Q + S E + +R+ E E+ K + E
Sbjct: 1494 YEESLDQLETLKRENKNLQQEI---------SDLTEQIAEGGKRIHELEKIKKQVEQEKC 1544
Query: 182 ETAARYNAAMGRMRQLEKKLKR---AINKSKPYFELK-AKYYVQLEQLKKT----VDDLQ 233
E A A + E K+ R +N+ K + K A+ +++QLK+ V+ +Q
Sbjct: 1545 ELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHIRIVESMQ 1604
Query: 234 AKL 236
+ L
Sbjct: 1605 STL 1607
Score = 36.2 bits (82), Expect = 0.063
Identities = 62/292 (21%), Positives = 128/292 (43%), Gaps = 37/292 (12%)
Query: 2 DAALKRSRSEEPAEILPPARDEEEEEEEGMEQGLEEEEEVDPRIQGELEKL---NQSTDD 58
+ A + ++ + L + + +E EE M L+E+ ++ ++Q E E L + D
Sbjct: 854 EMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLADAEERCDQ 913
Query: 59 INRRETELE----------DARQKFRSVLVEATVKLDELVKKIGKAVEDSKPYWEARRVA 108
+ + + +LE + ++ + L KL++ ++ K ++D +
Sbjct: 914 LIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLE--------L 965
Query: 109 RQAQLEAQK-ATQD-FQRATEVLRAAKETIS--LAEQRLLEDDKRQ-FDS--AWQEMLNH 161
A++E +K AT++ + TE + ETI+ E++ L++ +Q D A ++ +N
Sbjct: 966 TLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNT 1025
Query: 162 ATQRVMEAEQTKTRSE-LVHKETAARYNAAMGRMRQLEKKLKRAI-------NKSKPYFE 213
T+ ++ EQ E + +E R + + R+LE LK A N+ + E
Sbjct: 1026 LTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAK-RKLEGDLKLAQESIMDIENEKQQLDE 1084
Query: 214 LKAKYYVQLEQLKKTVDDLQAKLTLAKGEYKMALKNLEMISDEIHERRRSSA 265
K ++ L+ ++D QA + + K +E + +EI R S A
Sbjct: 1085 KLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRA 1136
Score = 35.8 bits (81), Expect = 0.082
Identities = 47/244 (19%), Positives = 103/244 (42%), Gaps = 34/244 (13%)
Query: 28 EEGMEQGLEEEEEVDPRIQGELEKLNQSTDDINRRETELEDARQKFRSVLVEATVKLDEL 87
EE ++Q LE + + +Q E+ L + + +R ELE +++ E L+E
Sbjct: 1495 EESLDQ-LETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEE- 1552
Query: 88 VKKIGKAVEDSKPYWEARRVARQAQLEAQKATQD---FQRATEVLRAAKETISLAE--QR 142
E S + E + + Q +L K+ D ++ E+ + + I + E Q
Sbjct: 1553 -------AEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHIRIVESMQS 1605
Query: 143 LLEDD----------KRQFDSAWQEM---LNHATQRVMEAEQTKTRSELVHKETAARYNA 189
L+ + K++ + EM LNHA + EA + ++ + K+T +
Sbjct: 1606 TLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDD 1665
Query: 190 AMGRMRQLEKKLKRAINKSKPYFELKAKYYVQLEQLKKTVDDLQAKLTLAKGEYKMALKN 249
A+ L+++L ++ ++E+L+ T++ + +A+ E A +
Sbjct: 1666 ALRSQEDLKEQLAMVERRAN-------LLQAEIEELRATLEQTERSRKIAEQELLDASER 1718
Query: 250 LEMI 253
++++
Sbjct: 1719 VQLL 1722
>gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 53.1 bits (126), Expect = 5e-07
Identities = 67/258 (25%), Positives = 115/258 (44%), Gaps = 28/258 (10%)
Query: 5 LKRSRSEE--PAEILPPARDEEEEEEEGMEQGLEEEEEVDPRIQGELEKLNQSTDDINRR 62
LKR EE L A + + + + EEE+E +Q L K N
Sbjct: 1321 LKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQRALSKAN--------- 1371
Query: 63 ETELEDARQKFRSVLVEATVKLDELVKKIGKAVEDSKPYWEARRVARQAQLEAQKATQDF 122
TE+ R K+ + ++ T +L+E KK+ + ++ ++ + EA A+ A LE K Q
Sbjct: 1372 -TEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVN-AKCASLE--KTKQRL 1427
Query: 123 QRATEVLRAAKETISLAEQRLLEDDKRQFD---SAWQEMLNHATQRVMEAEQTKTRS--- 176
Q E L E + A L+ +R FD + W++ T +EA Q + RS
Sbjct: 1428 QNEVEDLMLDVERTN-AACAALDKKQRNFDKILAEWKQKCEE-THAELEASQKEARSLGT 1485
Query: 177 ELVHKETAARYNAAMGRMRQLE---KKLKRAINKSKPYFELKAKYYVQLEQLKKTVDDLQ 233
EL + A Y ++ ++ L+ K L++ I+ K +LE++KK V+ +
Sbjct: 1486 ELFKIKNA--YEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEK 1543
Query: 234 AKLTLAKGEYKMALKNLE 251
+L A E + +L++ E
Sbjct: 1544 CELQAALEEAEASLEHEE 1561
Score = 42.7 bits (99), Expect = 7e-04
Identities = 56/262 (21%), Positives = 112/262 (42%), Gaps = 22/262 (8%)
Query: 11 EEPAEILPPARDEEEEEEEGMEQGLEEEEEVDPRIQGELEKLNQSTDDINRRETELEDAR 70
E+ L E + +EE ++ + + R+Q E + ++ D+ ++L +
Sbjct: 1252 EKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQLDEKEALVSQLSRGK 1311
Query: 71 QKFRSVLVEATVKLDELVK---KIGKAVEDSKPYWEARRVARQAQLEAQKATQDFQRA-- 125
Q F + E +L+E +K + A++ S+ + + R+ E Q++ + QRA
Sbjct: 1312 QAFTQQIEELKRQLEEEIKAKNALAHALQSSRHDCD---LLREQYEEEQESKAELQRALS 1368
Query: 126 ---TEVL--RAAKETISLAEQRLLEDDKRQFD---SAWQEMLNHATQRVMEAEQTKTRSE 177
TEV R ET ++ LE+ K++ A +E + + E+TK R +
Sbjct: 1369 KANTEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQ 1428
Query: 178 LVHKE---TAARYNAAMGRMRQLEKKLKRAINKSKPYFELKAKYYVQLEQLKKTVDDLQA 234
++ R NAA + + ++ + + + K E + + +LE +K L
Sbjct: 1429 NEVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQKCE---ETHAELEASQKEARSLGT 1485
Query: 235 KLTLAKGEYKMALKNLEMISDE 256
+L K Y+ +L LE + E
Sbjct: 1486 ELFKIKNAYEESLDQLETLKRE 1507
Score = 41.2 bits (95), Expect = 0.002
Identities = 51/271 (18%), Positives = 119/271 (43%), Gaps = 40/271 (14%)
Query: 10 SEEPAEILPPARDEEEEEEEGMEQGLEEEEEVDP-------RIQGELEKLNQSTDDINRR 62
+EE + L + + E + + + + E+EEE++ +++ E +L + DD+
Sbjct: 907 AEERCDQLIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELT 966
Query: 63 ETELEDARQKFRSVLVEATVKLDELVKKIGKAVEDSKPYWEARR--------------VA 108
++E + + + T ++ L + I K ++ K EA +
Sbjct: 967 LAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNTL 1026
Query: 109 RQAQLEAQKATQDFQRATEVLRAAKETISLAEQRLLEDDKRQFDSAWQEMLNHATQRVME 168
+A+++ ++ D + + E + + + A +R LE D + + ++ N Q ++
Sbjct: 1027 TKAKIKLEQQVDDLEGSLEQEKKLRMDLERA-KRKLEGDLKLAQESIMDIENEKQQ--LD 1083
Query: 169 AEQTKTRSELVHKETAARYNAAMGRMRQLEKKLKRAINKSKPYFELKAKYYVQLEQLKKT 228
+ K E+ + ++ A+G QL+KK+K EL+A+ +E+L++
Sbjct: 1084 EKLKKKEFEISNLQSKIEDEQALG--IQLQKKIK----------ELQAR----IEELEEE 1127
Query: 229 VDDLQAKLTLAKGEYKMALKNLEMISDEIHE 259
++ +A A+ + + LE IS+ + E
Sbjct: 1128 IEAERASRAKAEKQRSDLSRELEEISERLEE 1158
Score = 37.7 bits (86), Expect = 0.022
Identities = 51/243 (20%), Positives = 92/243 (37%), Gaps = 27/243 (11%)
Query: 2 DAALKRSRSEEPAEILPPARDEEEEEEEGMEQGLEEEEEVDPRIQGELEKLNQSTDDINR 61
DA + EE + L EE E + E+ R+Q E+E L + N
Sbjct: 1384 DAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNA 1443
Query: 62 RETELEDARQKFRSVLVEATVKLDELVKKIGKAVEDSKPYWEARRVARQAQLEAQKATQD 121
L+ ++ F +L E K +E ++ +++ AR E K
Sbjct: 1444 ACAALDKKQRNFDKILAEWKQKCEETHAELE----------ASQKEARSLGTELFKIKNA 1493
Query: 122 FQRATEVLRAAKETISLAEQRLLEDDKRQFDSAWQEMLNHATQRVMEAEQTKTRSELVHK 181
++ + + L K +Q + S E + +R+ E E+ K + E
Sbjct: 1494 YEESLDQLETLKRENKNLQQEI---------SDLTEQIAEGGKRIHELEKIKKQVEQEKC 1544
Query: 182 ETAARYNAAMGRMRQLEKKLKR---AINKSKPYFELK-AKYYVQLEQLKKT----VDDLQ 233
E A A + E K+ R +N+ K + K A+ +++QLK+ V+ +Q
Sbjct: 1545 ELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHIRIVESMQ 1604
Query: 234 AKL 236
+ L
Sbjct: 1605 STL 1607
Score = 36.2 bits (82), Expect = 0.063
Identities = 62/292 (21%), Positives = 128/292 (43%), Gaps = 37/292 (12%)
Query: 2 DAALKRSRSEEPAEILPPARDEEEEEEEGMEQGLEEEEEVDPRIQGELEKL---NQSTDD 58
+ A + ++ + L + + +E EE M L+E+ ++ ++Q E E L + D
Sbjct: 854 EMATMKEEFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLADAEERCDQ 913
Query: 59 INRRETELE----------DARQKFRSVLVEATVKLDELVKKIGKAVEDSKPYWEARRVA 108
+ + + +LE + ++ + L KL++ ++ K ++D +
Sbjct: 914 LIKTKIQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLE--------L 965
Query: 109 RQAQLEAQK-ATQD-FQRATEVLRAAKETIS--LAEQRLLEDDKRQ-FDS--AWQEMLNH 161
A++E +K AT++ + TE + ETI+ E++ L++ +Q D A ++ +N
Sbjct: 966 TLAKVEKEKHATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDKVNT 1025
Query: 162 ATQRVMEAEQTKTRSE-LVHKETAARYNAAMGRMRQLEKKLKRAI-------NKSKPYFE 213
T+ ++ EQ E + +E R + + R+LE LK A N+ + E
Sbjct: 1026 LTKAKIKLEQQVDDLEGSLEQEKKLRMDLERAK-RKLEGDLKLAQESIMDIENEKQQLDE 1084
Query: 214 LKAKYYVQLEQLKKTVDDLQAKLTLAKGEYKMALKNLEMISDEIHERRRSSA 265
K ++ L+ ++D QA + + K +E + +EI R S A
Sbjct: 1085 KLKKKEFEISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRA 1136
Score = 35.8 bits (81), Expect = 0.082
Identities = 47/244 (19%), Positives = 103/244 (42%), Gaps = 34/244 (13%)
Query: 28 EEGMEQGLEEEEEVDPRIQGELEKLNQSTDDINRRETELEDARQKFRSVLVEATVKLDEL 87
EE ++Q LE + + +Q E+ L + + +R ELE +++ E L+E
Sbjct: 1495 EESLDQ-LETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKCELQAALEE- 1552
Query: 88 VKKIGKAVEDSKPYWEARRVARQAQLEAQKATQD---FQRATEVLRAAKETISLAE--QR 142
E S + E + + Q +L K+ D ++ E+ + + I + E Q
Sbjct: 1553 -------AEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHIRIVESMQS 1605
Query: 143 LLEDD----------KRQFDSAWQEM---LNHATQRVMEAEQTKTRSELVHKETAARYNA 189
L+ + K++ + EM LNHA + EA + ++ + K+T +
Sbjct: 1606 TLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALRNYRNTQGILKDTQIHLDD 1665
Query: 190 AMGRMRQLEKKLKRAINKSKPYFELKAKYYVQLEQLKKTVDDLQAKLTLAKGEYKMALKN 249
A+ L+++L ++ ++E+L+ T++ + +A+ E A +
Sbjct: 1666 ALRSQEDLKEQLAMVERRAN-------LLQAEIEELRATLEQTERSRKIAEQELLDASER 1718
Query: 250 LEMI 253
++++
Sbjct: 1719 VQLL 1722
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 52.8 bits (125), Expect = 7e-07
Identities = 58/259 (22%), Positives = 114/259 (44%), Gaps = 24/259 (9%)
Query: 20 ARDEEEEE---EEGMEQGLEEEEEVD---PRIQGELEKLNQSTDDINRRETELEDARQKF 73
AR++E + +E+ LE +EE++ ++ E+E L S DD+ + ELE +++
Sbjct: 1478 AREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRAL 1537
Query: 74 RSVLVEATVKLDELVKKIGKAVEDSKPYWEARRVARQAQLEAQKATQDFQRATEVLRAAK 133
+ + E +L+EL ++ +A ED+K E A + Q E +D Q +
Sbjct: 1538 ETQMEEMKTQLEELEDEL-QATEDAKLRLEVNMQALKGQFERDLQARDEQN--------E 1588
Query: 134 ETISLAEQRLLEDDKRQFDSAWQEMLNHATQRVMEAE----QTKTRSELVHKETAAR-YN 188
E +++L E + D Q L A ++ +E + + + S + +E A +
Sbjct: 1589 EKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLR 1648
Query: 189 AAMGRMRQLEKKLKRAINKSKPYFELKAKYYVQLEQLKKTVDDLQAKLTLAKGEYKMALK 248
+M+ +++L+ A F + + + L+ + LQ L A + A K
Sbjct: 1649 KLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAA----ERARK 1704
Query: 249 NLEMISDEIHERRRSSAMG 267
++ +E+ E SS G
Sbjct: 1705 QADLEKEELAEELASSLSG 1723
Score = 51.6 bits (122), Expect = 1e-06
Identities = 58/264 (21%), Positives = 116/264 (43%), Gaps = 28/264 (10%)
Query: 24 EEEEEEGMEQGLEEEEEVDPRIQGELEKLNQS----TDDIN------RRETELEDARQKF 73
+EEE + E L++ +E + + EL++L Q T++ N + ETEL ++
Sbjct: 850 QEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEM 909
Query: 74 RSVLVEATVKLDELVKKIGKAVEDSKPYWE----ARRVARQAQLEAQKATQDFQRATEVL 129
R L +L+E++ ++ +E+ + + R+ Q L+ ++ ++ + A + L
Sbjct: 910 RVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKL 969
Query: 130 RAAKETI-----SLAEQRLLEDDKRQFDSAWQEMLNHATQRVMEAEQTKTRSELVHKETA 184
+ K T L ++ L+ DD+ S +++L +R+ + E K
Sbjct: 970 QLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLE---ERISDLTTNLAEEEEKAKNLT 1026
Query: 185 ARYNAAMGRMRQLEKKLKRAINKSKPYFELKAKYYVQLEQLKKTVDDLQA-----KLTLA 239
N + +LE +LK+ + +LK K + + DLQA K+ LA
Sbjct: 1027 KLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLA 1086
Query: 240 KGEYKMALKNLEMISDEIHERRRS 263
K E ++ L + DEI ++ +
Sbjct: 1087 KKEEELQAA-LARLDDEIAQKNNA 1109
Score = 50.8 bits (120), Expect = 2e-06
Identities = 57/254 (22%), Positives = 113/254 (44%), Gaps = 13/254 (5%)
Query: 8 SRSEEPAEILPPARDEEEEEEEGMEQGLEEEEEVDPRIQGELEKLNQSTDDINRRETELE 67
+ +EE L + E EE ME LEEEE+ ++Q E +K+ Q D+ + E E
Sbjct: 904 AEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEE 963
Query: 68 DARQKFRSVLVEATVKLDELVKKIGKAVEDSKPYWEARRV--ARQAQLEAQKATQD--FQ 123
ARQK + V A K+ +L +I + + + R++ R + L A ++ +
Sbjct: 964 AARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAK 1023
Query: 124 RATEVLRAAKETISLAEQRLLEDDKRQFDSAWQEMLNHATQRVMEAEQTKTRSELVHKET 183
T++ + IS E RL +++K + QE+ +R +E + + ++ +
Sbjct: 1024 NLTKLKNKHESMISELEVRLKKEEKSR-----QEL--EKLKRKLEGDASDFHEQIA--DL 1074
Query: 184 AARYNAAMGRMRQLEKKLKRAINKSKPYFELKAKYYVQLEQLKKTVDDLQAKLTLAKGEY 243
A+ ++ + E++L+ A+ + K ++ +L+ + DLQ L +
Sbjct: 1075 QAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAAR 1134
Query: 244 KMALKNLEMISDEI 257
A K + +E+
Sbjct: 1135 NKAEKQKRDLGEEL 1148
Score = 49.7 bits (117), Expect = 6e-06
Identities = 65/315 (20%), Positives = 127/315 (40%), Gaps = 26/315 (8%)
Query: 2 DAALKRSRSEEPAEILPPARDEEEEEEEGMEQGLEEE-------EEVDPRIQGELEKLNQ 54
D+ K E L + ++E E + Q EE+ E+ R+Q EL+ L
Sbjct: 1375 DSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVV 1434
Query: 55 STDDINRRETELEDARQKFRSVLVEATVKLDELVKKIGKAVEDSKPYWEARRVARQAQLE 114
D+ + + LE ++KF +L E + + +A +++ +A E
Sbjct: 1435 DLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEE 1494
Query: 115 AQKATQDFQRATEVLRAAKETISLAEQRL------LEDDKRQFDSAWQEM---LNHATQR 165
A +A ++ +R ++L+A E + ++ + LE KR ++ +EM L
Sbjct: 1495 ALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDE 1554
Query: 166 VMEAEQTKTRSELVHKETAARYNAAMGRMRQLEKKLKRAINKSKPYFELKAKYYVQLEQL 225
+ E K R E+ + ++ R L+ + ++ K + +Y +LE
Sbjct: 1555 LQATEDAKLRLEVNMQALKGQFE------RDLQARDEQNEEKRRQLQRQLHEYETELEDE 1608
Query: 226 KKTVDDLQAKLTLAKGEYKMALKNLEMISDEIHERRRSSAMGPRGCGVGAEGSSTSVEDL 285
+K +A AK + + LK+LE+ +D + R + R + +ED
Sbjct: 1609 RKQ----RALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDA 1664
Query: 286 PGSKPEPDAISVASE 300
S+ E A + +E
Sbjct: 1665 RASRDEIFATAKENE 1679
Score = 43.1 bits (100), Expect = 5e-04
Identities = 60/310 (19%), Positives = 125/310 (40%), Gaps = 52/310 (16%)
Query: 2 DAALKRSRSEEPAEILPPARDEEEEEEEGMEQGLEEEEE-------VDPRIQGELEKLNQ 54
D + EE A+ L +++ E +E L++EE+ + +++G+ ++
Sbjct: 1010 DLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHE 1069
Query: 55 STDDINRRETELEDARQKFRSVLVEATVKLDELVKKIGKA----------VEDSKPYWEA 104
D+ + EL+ K L A +LD+ + + A + D + ++
Sbjct: 1070 QIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDS 1129
Query: 105 RRVARQA----------QLEAQKA----TQDFQRATEVLRAAKETISLAEQRLLEDDKRQ 150
R AR +LEA K T D + LRA +E ++ L+++ R
Sbjct: 1130 ERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRS 1189
Query: 151 FDSAWQEMLNHATQRVME----AEQTKTRSELV--HKETAARYNAAMG------------ 192
++ QEM Q V E EQ K + +K+T + NA +
Sbjct: 1190 HEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQE 1249
Query: 193 ---RMRQLEKKLKRAINKSKPYFELKAKYYVQLEQLKKTVDDLQAKLTLAKGEYKMALKN 249
+ ++LE +++ +K +A+ ++ +L+ V+ + L A+G+ K+
Sbjct: 1250 VEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKD 1309
Query: 250 LEMISDEIHE 259
+ +S ++ +
Sbjct: 1310 VASLSSQLQD 1319
Score = 38.1 bits (87), Expect = 0.017
Identities = 52/240 (21%), Positives = 96/240 (40%), Gaps = 33/240 (13%)
Query: 25 EEEEEGMEQGLEEEEEVDPRIQGELEKLNQSTDDINRRETELEDARQKFRSVLVEATVKL 84
EEE ++ L+EE E ++ + LN +L D+++K + L
Sbjct: 1342 EEERNSLQDQLDEEMEAKQNLERHISTLN----------IQLSDSKKKLQD-FASTVEAL 1390
Query: 85 DELVKKIGKAVEDSKPYWEARRVARQAQLEAQKATQDFQRATEVLRAAKETISLAEQRL- 143
+E K+ K +E+ +E + A + +K Q+ + L + L QR
Sbjct: 1391 EEGKKRFQKEIENLTQQYEEKAAAYD---KLEKTKNRLQQELDDL-----VVDLDNQRQL 1442
Query: 144 ---LEDDKRQFDSAWQEMLNHATQRVMEAEQTKTRSELVHKETAARYNAAMGRMRQLEKK 200
LE +R+FD E N +++ E+ + +E KET A+ R LE+
Sbjct: 1443 VSNLEKKQRKFDQLLAEEKNISSK--YADERDRAEAEAREKET-----KALSLARALEEA 1495
Query: 201 LKRAINKSKPYFELKAK---YYVQLEQLKKTVDDLQAKLTLAKGEYKMALKNLEMISDEI 257
L+ + LKA+ + + K V +L+ + + + LE + DE+
Sbjct: 1496 LEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDEL 1555
Score = 37.7 bits (86), Expect = 0.022
Identities = 50/209 (23%), Positives = 89/209 (42%), Gaps = 32/209 (15%)
Query: 21 RDEEEEEEEGMEQGLEEEEEVDPRIQGELEKLNQSTDDINRRETEL----------EDAR 70
+DE+ E + Q EE EE ++ +++ ++T + EL E AR
Sbjct: 1728 QDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESAR 1787
Query: 71 QKFRSVLVEATVKLDELVKKIGKAVEDSKPYWEARRVARQAQLEAQ--KATQDFQRATEV 128
Q+ E KL E+ + + + EA+ AQLE Q + ++ Q AT+
Sbjct: 1788 QQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKI----AQLEEQVEQEAREKQAATKS 1843
Query: 129 LRAAKETISLAEQRLLEDDKRQFDSAWQEMLNHATQRV----MEAEQTKTRSELVHK--- 181
L+ ++ L E L +D+R+ ++E RV + E+ + S+ ++
Sbjct: 1844 LK--QKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRR 1901
Query: 182 ------ETAARYNAAMGR-MRQLEKKLKR 203
+ A N AMGR + L+ KL+R
Sbjct: 1902 KLQRELDEATESNEAMGREVNALKSKLRR 1930
>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
sapiens]
Length = 1979
Score = 52.8 bits (125), Expect = 7e-07
Identities = 58/259 (22%), Positives = 114/259 (44%), Gaps = 24/259 (9%)
Query: 20 ARDEEEEE---EEGMEQGLEEEEEVD---PRIQGELEKLNQSTDDINRRETELEDARQKF 73
AR++E + +E+ LE +EE++ ++ E+E L S DD+ + ELE +++
Sbjct: 1485 AREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRAL 1544
Query: 74 RSVLVEATVKLDELVKKIGKAVEDSKPYWEARRVARQAQLEAQKATQDFQRATEVLRAAK 133
+ + E +L+EL ++ +A ED+K E A + Q E +D Q +
Sbjct: 1545 ETQMEEMKTQLEELEDEL-QATEDAKLRLEVNMQALKGQFERDLQARDEQN--------E 1595
Query: 134 ETISLAEQRLLEDDKRQFDSAWQEMLNHATQRVMEAE----QTKTRSELVHKETAAR-YN 188
E +++L E + D Q L A ++ +E + + + S + +E A +
Sbjct: 1596 EKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLR 1655
Query: 189 AAMGRMRQLEKKLKRAINKSKPYFELKAKYYVQLEQLKKTVDDLQAKLTLAKGEYKMALK 248
+M+ +++L+ A F + + + L+ + LQ L A + A K
Sbjct: 1656 KLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAA----ERARK 1711
Query: 249 NLEMISDEIHERRRSSAMG 267
++ +E+ E SS G
Sbjct: 1712 QADLEKEELAEELASSLSG 1730
Score = 51.6 bits (122), Expect = 1e-06
Identities = 58/264 (21%), Positives = 116/264 (43%), Gaps = 28/264 (10%)
Query: 24 EEEEEEGMEQGLEEEEEVDPRIQGELEKLNQS----TDDIN------RRETELEDARQKF 73
+EEE + E L++ +E + + EL++L Q T++ N + ETEL ++
Sbjct: 857 QEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEM 916
Query: 74 RSVLVEATVKLDELVKKIGKAVEDSKPYWE----ARRVARQAQLEAQKATQDFQRATEVL 129
R L +L+E++ ++ +E+ + + R+ Q L+ ++ ++ + A + L
Sbjct: 917 RVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKL 976
Query: 130 RAAKETI-----SLAEQRLLEDDKRQFDSAWQEMLNHATQRVMEAEQTKTRSELVHKETA 184
+ K T L ++ L+ DD+ S +++L +R+ + E K
Sbjct: 977 QLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLE---ERISDLTTNLAEEEEKAKNLT 1033
Query: 185 ARYNAAMGRMRQLEKKLKRAINKSKPYFELKAKYYVQLEQLKKTVDDLQA-----KLTLA 239
N + +LE +LK+ + +LK K + + DLQA K+ LA
Sbjct: 1034 KLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLA 1093
Query: 240 KGEYKMALKNLEMISDEIHERRRS 263
K E ++ L + DEI ++ +
Sbjct: 1094 KKEEELQAA-LARLDDEIAQKNNA 1116
Score = 50.8 bits (120), Expect = 2e-06
Identities = 57/254 (22%), Positives = 113/254 (44%), Gaps = 13/254 (5%)
Query: 8 SRSEEPAEILPPARDEEEEEEEGMEQGLEEEEEVDPRIQGELEKLNQSTDDINRRETELE 67
+ +EE L + E EE ME LEEEE+ ++Q E +K+ Q D+ + E E
Sbjct: 911 AEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEE 970
Query: 68 DARQKFRSVLVEATVKLDELVKKIGKAVEDSKPYWEARRV--ARQAQLEAQKATQD--FQ 123
ARQK + V A K+ +L +I + + + R++ R + L A ++ +
Sbjct: 971 AARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAK 1030
Query: 124 RATEVLRAAKETISLAEQRLLEDDKRQFDSAWQEMLNHATQRVMEAEQTKTRSELVHKET 183
T++ + IS E RL +++K + QE+ +R +E + + ++ +
Sbjct: 1031 NLTKLKNKHESMISELEVRLKKEEKSR-----QEL--EKLKRKLEGDASDFHEQIA--DL 1081
Query: 184 AARYNAAMGRMRQLEKKLKRAINKSKPYFELKAKYYVQLEQLKKTVDDLQAKLTLAKGEY 243
A+ ++ + E++L+ A+ + K ++ +L+ + DLQ L +
Sbjct: 1082 QAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAAR 1141
Query: 244 KMALKNLEMISDEI 257
A K + +E+
Sbjct: 1142 NKAEKQKRDLGEEL 1155
Score = 49.7 bits (117), Expect = 6e-06
Identities = 65/315 (20%), Positives = 127/315 (40%), Gaps = 26/315 (8%)
Query: 2 DAALKRSRSEEPAEILPPARDEEEEEEEGMEQGLEEE-------EEVDPRIQGELEKLNQ 54
D+ K E L + ++E E + Q EE+ E+ R+Q EL+ L
Sbjct: 1382 DSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVV 1441
Query: 55 STDDINRRETELEDARQKFRSVLVEATVKLDELVKKIGKAVEDSKPYWEARRVARQAQLE 114
D+ + + LE ++KF +L E + + +A +++ +A E
Sbjct: 1442 DLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEE 1501
Query: 115 AQKATQDFQRATEVLRAAKETISLAEQRL------LEDDKRQFDSAWQEM---LNHATQR 165
A +A ++ +R ++L+A E + ++ + LE KR ++ +EM L
Sbjct: 1502 ALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDE 1561
Query: 166 VMEAEQTKTRSELVHKETAARYNAAMGRMRQLEKKLKRAINKSKPYFELKAKYYVQLEQL 225
+ E K R E+ + ++ R L+ + ++ K + +Y +LE
Sbjct: 1562 LQATEDAKLRLEVNMQALKGQFE------RDLQARDEQNEEKRRQLQRQLHEYETELEDE 1615
Query: 226 KKTVDDLQAKLTLAKGEYKMALKNLEMISDEIHERRRSSAMGPRGCGVGAEGSSTSVEDL 285
+K +A AK + + LK+LE+ +D + R + R + +ED
Sbjct: 1616 RKQ----RALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDA 1671
Query: 286 PGSKPEPDAISVASE 300
S+ E A + +E
Sbjct: 1672 RASRDEIFATAKENE 1686
Score = 43.1 bits (100), Expect = 5e-04
Identities = 60/310 (19%), Positives = 125/310 (40%), Gaps = 52/310 (16%)
Query: 2 DAALKRSRSEEPAEILPPARDEEEEEEEGMEQGLEEEEE-------VDPRIQGELEKLNQ 54
D + EE A+ L +++ E +E L++EE+ + +++G+ ++
Sbjct: 1017 DLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHE 1076
Query: 55 STDDINRRETELEDARQKFRSVLVEATVKLDELVKKIGKA----------VEDSKPYWEA 104
D+ + EL+ K L A +LD+ + + A + D + ++
Sbjct: 1077 QIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDS 1136
Query: 105 RRVARQA----------QLEAQKA----TQDFQRATEVLRAAKETISLAEQRLLEDDKRQ 150
R AR +LEA K T D + LRA +E ++ L+++ R
Sbjct: 1137 ERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRS 1196
Query: 151 FDSAWQEMLNHATQRVME----AEQTKTRSELV--HKETAARYNAAMG------------ 192
++ QEM Q V E EQ K + +K+T + NA +
Sbjct: 1197 HEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQE 1256
Query: 193 ---RMRQLEKKLKRAINKSKPYFELKAKYYVQLEQLKKTVDDLQAKLTLAKGEYKMALKN 249
+ ++LE +++ +K +A+ ++ +L+ V+ + L A+G+ K+
Sbjct: 1257 VEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKD 1316
Query: 250 LEMISDEIHE 259
+ +S ++ +
Sbjct: 1317 VASLSSQLQD 1326
Score = 38.1 bits (87), Expect = 0.017
Identities = 52/240 (21%), Positives = 96/240 (40%), Gaps = 33/240 (13%)
Query: 25 EEEEEGMEQGLEEEEEVDPRIQGELEKLNQSTDDINRRETELEDARQKFRSVLVEATVKL 84
EEE ++ L+EE E ++ + LN +L D+++K + L
Sbjct: 1349 EEERNSLQDQLDEEMEAKQNLERHISTLN----------IQLSDSKKKLQD-FASTVEAL 1397
Query: 85 DELVKKIGKAVEDSKPYWEARRVARQAQLEAQKATQDFQRATEVLRAAKETISLAEQRL- 143
+E K+ K +E+ +E + A + +K Q+ + L + L QR
Sbjct: 1398 EEGKKRFQKEIENLTQQYEEKAAAYD---KLEKTKNRLQQELDDL-----VVDLDNQRQL 1449
Query: 144 ---LEDDKRQFDSAWQEMLNHATQRVMEAEQTKTRSELVHKETAARYNAAMGRMRQLEKK 200
LE +R+FD E N +++ E+ + +E KET A+ R LE+
Sbjct: 1450 VSNLEKKQRKFDQLLAEEKNISSK--YADERDRAEAEAREKET-----KALSLARALEEA 1502
Query: 201 LKRAINKSKPYFELKAK---YYVQLEQLKKTVDDLQAKLTLAKGEYKMALKNLEMISDEI 257
L+ + LKA+ + + K V +L+ + + + LE + DE+
Sbjct: 1503 LEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDEL 1562
Score = 37.7 bits (86), Expect = 0.022
Identities = 50/209 (23%), Positives = 89/209 (42%), Gaps = 32/209 (15%)
Query: 21 RDEEEEEEEGMEQGLEEEEEVDPRIQGELEKLNQSTDDINRRETEL----------EDAR 70
+DE+ E + Q EE EE ++ +++ ++T + EL E AR
Sbjct: 1735 QDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESAR 1794
Query: 71 QKFRSVLVEATVKLDELVKKIGKAVEDSKPYWEARRVARQAQLEAQ--KATQDFQRATEV 128
Q+ E KL E+ + + + EA+ AQLE Q + ++ Q AT+
Sbjct: 1795 QQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKI----AQLEEQVEQEAREKQAATKS 1850
Query: 129 LRAAKETISLAEQRLLEDDKRQFDSAWQEMLNHATQRV----MEAEQTKTRSELVHK--- 181
L+ ++ L E L +D+R+ ++E RV + E+ + S+ ++
Sbjct: 1851 LK--QKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRINANRR 1908
Query: 182 ------ETAARYNAAMGR-MRQLEKKLKR 203
+ A N AMGR + L+ KL+R
Sbjct: 1909 KLQRELDEATESNEAMGREVNALKSKLRR 1937
>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
sapiens]
Length = 1945
Score = 52.8 bits (125), Expect = 7e-07
Identities = 58/259 (22%), Positives = 114/259 (44%), Gaps = 24/259 (9%)
Query: 20 ARDEEEEE---EEGMEQGLEEEEEVD---PRIQGELEKLNQSTDDINRRETELEDARQKF 73
AR++E + +E+ LE +EE++ ++ E+E L S DD+ + ELE +++
Sbjct: 1485 AREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRAL 1544
Query: 74 RSVLVEATVKLDELVKKIGKAVEDSKPYWEARRVARQAQLEAQKATQDFQRATEVLRAAK 133
+ + E +L+EL ++ +A ED+K E A + Q E +D Q +
Sbjct: 1545 ETQMEEMKTQLEELEDEL-QATEDAKLRLEVNMQALKGQFERDLQARDEQN--------E 1595
Query: 134 ETISLAEQRLLEDDKRQFDSAWQEMLNHATQRVMEAE----QTKTRSELVHKETAAR-YN 188
E +++L E + D Q L A ++ +E + + + S + +E A +
Sbjct: 1596 EKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLR 1655
Query: 189 AAMGRMRQLEKKLKRAINKSKPYFELKAKYYVQLEQLKKTVDDLQAKLTLAKGEYKMALK 248
+M+ +++L+ A F + + + L+ + LQ L A + A K
Sbjct: 1656 KLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAA----ERARK 1711
Query: 249 NLEMISDEIHERRRSSAMG 267
++ +E+ E SS G
Sbjct: 1712 QADLEKEELAEELASSLSG 1730
Score = 51.6 bits (122), Expect = 1e-06
Identities = 58/264 (21%), Positives = 116/264 (43%), Gaps = 28/264 (10%)
Query: 24 EEEEEEGMEQGLEEEEEVDPRIQGELEKLNQS----TDDIN------RRETELEDARQKF 73
+EEE + E L++ +E + + EL++L Q T++ N + ETEL ++
Sbjct: 857 QEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEM 916
Query: 74 RSVLVEATVKLDELVKKIGKAVEDSKPYWE----ARRVARQAQLEAQKATQDFQRATEVL 129
R L +L+E++ ++ +E+ + + R+ Q L+ ++ ++ + A + L
Sbjct: 917 RVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKL 976
Query: 130 RAAKETI-----SLAEQRLLEDDKRQFDSAWQEMLNHATQRVMEAEQTKTRSELVHKETA 184
+ K T L ++ L+ DD+ S +++L +R+ + E K
Sbjct: 977 QLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLE---ERISDLTTNLAEEEEKAKNLT 1033
Query: 185 ARYNAAMGRMRQLEKKLKRAINKSKPYFELKAKYYVQLEQLKKTVDDLQA-----KLTLA 239
N + +LE +LK+ + +LK K + + DLQA K+ LA
Sbjct: 1034 KLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLA 1093
Query: 240 KGEYKMALKNLEMISDEIHERRRS 263
K E ++ L + DEI ++ +
Sbjct: 1094 KKEEELQAA-LARLDDEIAQKNNA 1116
Score = 50.8 bits (120), Expect = 2e-06
Identities = 57/254 (22%), Positives = 113/254 (44%), Gaps = 13/254 (5%)
Query: 8 SRSEEPAEILPPARDEEEEEEEGMEQGLEEEEEVDPRIQGELEKLNQSTDDINRRETELE 67
+ +EE L + E EE ME LEEEE+ ++Q E +K+ Q D+ + E E
Sbjct: 911 AEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEE 970
Query: 68 DARQKFRSVLVEATVKLDELVKKIGKAVEDSKPYWEARRV--ARQAQLEAQKATQD--FQ 123
ARQK + V A K+ +L +I + + + R++ R + L A ++ +
Sbjct: 971 AARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAK 1030
Query: 124 RATEVLRAAKETISLAEQRLLEDDKRQFDSAWQEMLNHATQRVMEAEQTKTRSELVHKET 183
T++ + IS E RL +++K + QE+ +R +E + + ++ +
Sbjct: 1031 NLTKLKNKHESMISELEVRLKKEEKSR-----QEL--EKLKRKLEGDASDFHEQIA--DL 1081
Query: 184 AARYNAAMGRMRQLEKKLKRAINKSKPYFELKAKYYVQLEQLKKTVDDLQAKLTLAKGEY 243
A+ ++ + E++L+ A+ + K ++ +L+ + DLQ L +
Sbjct: 1082 QAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAAR 1141
Query: 244 KMALKNLEMISDEI 257
A K + +E+
Sbjct: 1142 NKAEKQKRDLGEEL 1155
Score = 49.7 bits (117), Expect = 6e-06
Identities = 65/315 (20%), Positives = 127/315 (40%), Gaps = 26/315 (8%)
Query: 2 DAALKRSRSEEPAEILPPARDEEEEEEEGMEQGLEEE-------EEVDPRIQGELEKLNQ 54
D+ K E L + ++E E + Q EE+ E+ R+Q EL+ L
Sbjct: 1382 DSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVV 1441
Query: 55 STDDINRRETELEDARQKFRSVLVEATVKLDELVKKIGKAVEDSKPYWEARRVARQAQLE 114
D+ + + LE ++KF +L E + + +A +++ +A E
Sbjct: 1442 DLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEE 1501
Query: 115 AQKATQDFQRATEVLRAAKETISLAEQRL------LEDDKRQFDSAWQEM---LNHATQR 165
A +A ++ +R ++L+A E + ++ + LE KR ++ +EM L
Sbjct: 1502 ALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDE 1561
Query: 166 VMEAEQTKTRSELVHKETAARYNAAMGRMRQLEKKLKRAINKSKPYFELKAKYYVQLEQL 225
+ E K R E+ + ++ R L+ + ++ K + +Y +LE
Sbjct: 1562 LQATEDAKLRLEVNMQALKGQFE------RDLQARDEQNEEKRRQLQRQLHEYETELEDE 1615
Query: 226 KKTVDDLQAKLTLAKGEYKMALKNLEMISDEIHERRRSSAMGPRGCGVGAEGSSTSVEDL 285
+K +A AK + + LK+LE+ +D + R + R + +ED
Sbjct: 1616 RKQ----RALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDA 1671
Query: 286 PGSKPEPDAISVASE 300
S+ E A + +E
Sbjct: 1672 RASRDEIFATAKENE 1686
Score = 43.1 bits (100), Expect = 5e-04
Identities = 60/310 (19%), Positives = 125/310 (40%), Gaps = 52/310 (16%)
Query: 2 DAALKRSRSEEPAEILPPARDEEEEEEEGMEQGLEEEEE-------VDPRIQGELEKLNQ 54
D + EE A+ L +++ E +E L++EE+ + +++G+ ++
Sbjct: 1017 DLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHE 1076
Query: 55 STDDINRRETELEDARQKFRSVLVEATVKLDELVKKIGKA----------VEDSKPYWEA 104
D+ + EL+ K L A +LD+ + + A + D + ++
Sbjct: 1077 QIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDS 1136
Query: 105 RRVARQA----------QLEAQKA----TQDFQRATEVLRAAKETISLAEQRLLEDDKRQ 150
R AR +LEA K T D + LRA +E ++ L+++ R
Sbjct: 1137 ERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRS 1196
Query: 151 FDSAWQEMLNHATQRVME----AEQTKTRSELV--HKETAARYNAAMG------------ 192
++ QEM Q V E EQ K + +K+T + NA +
Sbjct: 1197 HEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQE 1256
Query: 193 ---RMRQLEKKLKRAINKSKPYFELKAKYYVQLEQLKKTVDDLQAKLTLAKGEYKMALKN 249
+ ++LE +++ +K +A+ ++ +L+ V+ + L A+G+ K+
Sbjct: 1257 VEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKD 1316
Query: 250 LEMISDEIHE 259
+ +S ++ +
Sbjct: 1317 VASLSSQLQD 1326
Score = 38.1 bits (87), Expect = 0.017
Identities = 52/240 (21%), Positives = 96/240 (40%), Gaps = 33/240 (13%)
Query: 25 EEEEEGMEQGLEEEEEVDPRIQGELEKLNQSTDDINRRETELEDARQKFRSVLVEATVKL 84
EEE ++ L+EE E ++ + LN +L D+++K + L
Sbjct: 1349 EEERNSLQDQLDEEMEAKQNLERHISTLN----------IQLSDSKKKLQD-FASTVEAL 1397
Query: 85 DELVKKIGKAVEDSKPYWEARRVARQAQLEAQKATQDFQRATEVLRAAKETISLAEQRL- 143
+E K+ K +E+ +E + A + +K Q+ + L + L QR
Sbjct: 1398 EEGKKRFQKEIENLTQQYEEKAAAYD---KLEKTKNRLQQELDDL-----VVDLDNQRQL 1449
Query: 144 ---LEDDKRQFDSAWQEMLNHATQRVMEAEQTKTRSELVHKETAARYNAAMGRMRQLEKK 200
LE +R+FD E N +++ E+ + +E KET A+ R LE+
Sbjct: 1450 VSNLEKKQRKFDQLLAEEKNISSK--YADERDRAEAEAREKET-----KALSLARALEEA 1502
Query: 201 LKRAINKSKPYFELKAK---YYVQLEQLKKTVDDLQAKLTLAKGEYKMALKNLEMISDEI 257
L+ + LKA+ + + K V +L+ + + + LE + DE+
Sbjct: 1503 LEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDEL 1562
Score = 37.4 bits (85), Expect = 0.028
Identities = 47/201 (23%), Positives = 87/201 (43%), Gaps = 25/201 (12%)
Query: 21 RDEEEEEEEGMEQGLEEEEEVDPRIQGELEKLNQSTDDINRRETEL----------EDAR 70
+DE+ E + Q EE EE ++ +++ ++T + EL E AR
Sbjct: 1735 QDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESAR 1794
Query: 71 QKFRSVLVEATVKLDELVKKIGKAVEDSKPYWEARRVARQAQLEAQ--KATQDFQRATEV 128
Q+ E KL E+ + + + EA+ AQLE Q + ++ Q AT+
Sbjct: 1795 QQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKI----AQLEEQVEQEAREKQAATKS 1850
Query: 129 LRAAKETISLAEQRLLEDDKRQFDSAWQEMLNHATQRVMEAEQTKTRSELVHKETAARYN 188
L+ ++ L E L +D+R+ ++E RV + ++ +E E + R N
Sbjct: 1851 LK--QKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAE----EESQRIN 1904
Query: 189 AAMGRMRQLEKKLKRAINKSK 209
A R+L+++L A ++
Sbjct: 1905 A---NRRKLQRELDEATESNE 1922
>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
sapiens]
Length = 1938
Score = 52.8 bits (125), Expect = 7e-07
Identities = 58/259 (22%), Positives = 114/259 (44%), Gaps = 24/259 (9%)
Query: 20 ARDEEEEE---EEGMEQGLEEEEEVD---PRIQGELEKLNQSTDDINRRETELEDARQKF 73
AR++E + +E+ LE +EE++ ++ E+E L S DD+ + ELE +++
Sbjct: 1478 AREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRAL 1537
Query: 74 RSVLVEATVKLDELVKKIGKAVEDSKPYWEARRVARQAQLEAQKATQDFQRATEVLRAAK 133
+ + E +L+EL ++ +A ED+K E A + Q E +D Q +
Sbjct: 1538 ETQMEEMKTQLEELEDEL-QATEDAKLRLEVNMQALKGQFERDLQARDEQN--------E 1588
Query: 134 ETISLAEQRLLEDDKRQFDSAWQEMLNHATQRVMEAE----QTKTRSELVHKETAAR-YN 188
E +++L E + D Q L A ++ +E + + + S + +E A +
Sbjct: 1589 EKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLR 1648
Query: 189 AAMGRMRQLEKKLKRAINKSKPYFELKAKYYVQLEQLKKTVDDLQAKLTLAKGEYKMALK 248
+M+ +++L+ A F + + + L+ + LQ L A + A K
Sbjct: 1649 KLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAA----ERARK 1704
Query: 249 NLEMISDEIHERRRSSAMG 267
++ +E+ E SS G
Sbjct: 1705 QADLEKEELAEELASSLSG 1723
Score = 51.6 bits (122), Expect = 1e-06
Identities = 58/264 (21%), Positives = 116/264 (43%), Gaps = 28/264 (10%)
Query: 24 EEEEEEGMEQGLEEEEEVDPRIQGELEKLNQS----TDDIN------RRETELEDARQKF 73
+EEE + E L++ +E + + EL++L Q T++ N + ETEL ++
Sbjct: 850 QEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQLQAETELYAEAEEM 909
Query: 74 RSVLVEATVKLDELVKKIGKAVEDSKPYWE----ARRVARQAQLEAQKATQDFQRATEVL 129
R L +L+E++ ++ +E+ + + R+ Q L+ ++ ++ + A + L
Sbjct: 910 RVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQKL 969
Query: 130 RAAKETI-----SLAEQRLLEDDKRQFDSAWQEMLNHATQRVMEAEQTKTRSELVHKETA 184
+ K T L ++ L+ DD+ S +++L +R+ + E K
Sbjct: 970 QLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLE---ERISDLTTNLAEEEEKAKNLT 1026
Query: 185 ARYNAAMGRMRQLEKKLKRAINKSKPYFELKAKYYVQLEQLKKTVDDLQA-----KLTLA 239
N + +LE +LK+ + +LK K + + DLQA K+ LA
Sbjct: 1027 KLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLA 1086
Query: 240 KGEYKMALKNLEMISDEIHERRRS 263
K E ++ L + DEI ++ +
Sbjct: 1087 KKEEELQAA-LARLDDEIAQKNNA 1109
Score = 50.8 bits (120), Expect = 2e-06
Identities = 57/254 (22%), Positives = 113/254 (44%), Gaps = 13/254 (5%)
Query: 8 SRSEEPAEILPPARDEEEEEEEGMEQGLEEEEEVDPRIQGELEKLNQSTDDINRRETELE 67
+ +EE L + E EE ME LEEEE+ ++Q E +K+ Q D+ + E E
Sbjct: 904 AEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLDLEEQLEEEE 963
Query: 68 DARQKFRSVLVEATVKLDELVKKIGKAVEDSKPYWEARRV--ARQAQLEAQKATQD--FQ 123
ARQK + V A K+ +L +I + + + R++ R + L A ++ +
Sbjct: 964 AARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAK 1023
Query: 124 RATEVLRAAKETISLAEQRLLEDDKRQFDSAWQEMLNHATQRVMEAEQTKTRSELVHKET 183
T++ + IS E RL +++K + QE+ +R +E + + ++ +
Sbjct: 1024 NLTKLKNKHESMISELEVRLKKEEKSR-----QEL--EKLKRKLEGDASDFHEQIA--DL 1074
Query: 184 AARYNAAMGRMRQLEKKLKRAINKSKPYFELKAKYYVQLEQLKKTVDDLQAKLTLAKGEY 243
A+ ++ + E++L+ A+ + K ++ +L+ + DLQ L +
Sbjct: 1075 QAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAAR 1134
Query: 244 KMALKNLEMISDEI 257
A K + +E+
Sbjct: 1135 NKAEKQKRDLGEEL 1148
Score = 49.7 bits (117), Expect = 6e-06
Identities = 65/315 (20%), Positives = 127/315 (40%), Gaps = 26/315 (8%)
Query: 2 DAALKRSRSEEPAEILPPARDEEEEEEEGMEQGLEEE-------EEVDPRIQGELEKLNQ 54
D+ K E L + ++E E + Q EE+ E+ R+Q EL+ L
Sbjct: 1375 DSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVV 1434
Query: 55 STDDINRRETELEDARQKFRSVLVEATVKLDELVKKIGKAVEDSKPYWEARRVARQAQLE 114
D+ + + LE ++KF +L E + + +A +++ +A E
Sbjct: 1435 DLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEE 1494
Query: 115 AQKATQDFQRATEVLRAAKETISLAEQRL------LEDDKRQFDSAWQEM---LNHATQR 165
A +A ++ +R ++L+A E + ++ + LE KR ++ +EM L
Sbjct: 1495 ALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDE 1554
Query: 166 VMEAEQTKTRSELVHKETAARYNAAMGRMRQLEKKLKRAINKSKPYFELKAKYYVQLEQL 225
+ E K R E+ + ++ R L+ + ++ K + +Y +LE
Sbjct: 1555 LQATEDAKLRLEVNMQALKGQFE------RDLQARDEQNEEKRRQLQRQLHEYETELEDE 1608
Query: 226 KKTVDDLQAKLTLAKGEYKMALKNLEMISDEIHERRRSSAMGPRGCGVGAEGSSTSVEDL 285
+K +A AK + + LK+LE+ +D + R + R + +ED
Sbjct: 1609 RKQ----RALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDA 1664
Query: 286 PGSKPEPDAISVASE 300
S+ E A + +E
Sbjct: 1665 RASRDEIFATAKENE 1679
Score = 43.1 bits (100), Expect = 5e-04
Identities = 60/310 (19%), Positives = 125/310 (40%), Gaps = 52/310 (16%)
Query: 2 DAALKRSRSEEPAEILPPARDEEEEEEEGMEQGLEEEEE-------VDPRIQGELEKLNQ 54
D + EE A+ L +++ E +E L++EE+ + +++G+ ++
Sbjct: 1010 DLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHE 1069
Query: 55 STDDINRRETELEDARQKFRSVLVEATVKLDELVKKIGKA----------VEDSKPYWEA 104
D+ + EL+ K L A +LD+ + + A + D + ++
Sbjct: 1070 QIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDS 1129
Query: 105 RRVARQA----------QLEAQKA----TQDFQRATEVLRAAKETISLAEQRLLEDDKRQ 150
R AR +LEA K T D + LRA +E ++ L+++ R
Sbjct: 1130 ERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRS 1189
Query: 151 FDSAWQEMLNHATQRVME----AEQTKTRSELV--HKETAARYNAAMG------------ 192
++ QEM Q V E EQ K + +K+T + NA +
Sbjct: 1190 HEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQE 1249
Query: 193 ---RMRQLEKKLKRAINKSKPYFELKAKYYVQLEQLKKTVDDLQAKLTLAKGEYKMALKN 249
+ ++LE +++ +K +A+ ++ +L+ V+ + L A+G+ K+
Sbjct: 1250 VEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKD 1309
Query: 250 LEMISDEIHE 259
+ +S ++ +
Sbjct: 1310 VASLSSQLQD 1319
Score = 38.1 bits (87), Expect = 0.017
Identities = 52/240 (21%), Positives = 96/240 (40%), Gaps = 33/240 (13%)
Query: 25 EEEEEGMEQGLEEEEEVDPRIQGELEKLNQSTDDINRRETELEDARQKFRSVLVEATVKL 84
EEE ++ L+EE E ++ + LN +L D+++K + L
Sbjct: 1342 EEERNSLQDQLDEEMEAKQNLERHISTLN----------IQLSDSKKKLQD-FASTVEAL 1390
Query: 85 DELVKKIGKAVEDSKPYWEARRVARQAQLEAQKATQDFQRATEVLRAAKETISLAEQRL- 143
+E K+ K +E+ +E + A + +K Q+ + L + L QR
Sbjct: 1391 EEGKKRFQKEIENLTQQYEEKAAAYD---KLEKTKNRLQQELDDL-----VVDLDNQRQL 1442
Query: 144 ---LEDDKRQFDSAWQEMLNHATQRVMEAEQTKTRSELVHKETAARYNAAMGRMRQLEKK 200
LE +R+FD E N +++ E+ + +E KET A+ R LE+
Sbjct: 1443 VSNLEKKQRKFDQLLAEEKNISSK--YADERDRAEAEAREKET-----KALSLARALEEA 1495
Query: 201 LKRAINKSKPYFELKAK---YYVQLEQLKKTVDDLQAKLTLAKGEYKMALKNLEMISDEI 257
L+ + LKA+ + + K V +L+ + + + LE + DE+
Sbjct: 1496 LEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDEL 1555
Score = 37.4 bits (85), Expect = 0.028
Identities = 47/201 (23%), Positives = 87/201 (43%), Gaps = 25/201 (12%)
Query: 21 RDEEEEEEEGMEQGLEEEEEVDPRIQGELEKLNQSTDDINRRETEL----------EDAR 70
+DE+ E + Q EE EE ++ +++ ++T + EL E AR
Sbjct: 1728 QDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESAR 1787
Query: 71 QKFRSVLVEATVKLDELVKKIGKAVEDSKPYWEARRVARQAQLEAQ--KATQDFQRATEV 128
Q+ E KL E+ + + + EA+ AQLE Q + ++ Q AT+
Sbjct: 1788 QQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKI----AQLEEQVEQEAREKQAATKS 1843
Query: 129 LRAAKETISLAEQRLLEDDKRQFDSAWQEMLNHATQRVMEAEQTKTRSELVHKETAARYN 188
L+ ++ L E L +D+R+ ++E RV + ++ +E E + R N
Sbjct: 1844 LK--QKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAE----EESQRIN 1897
Query: 189 AAMGRMRQLEKKLKRAINKSK 209
A R+L+++L A ++
Sbjct: 1898 A---NRRKLQRELDEATESNE 1915
>gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta [Homo
sapiens]
Length = 1983
Score = 52.8 bits (125), Expect = 7e-07
Identities = 53/224 (23%), Positives = 103/224 (45%), Gaps = 26/224 (11%)
Query: 35 LEEEEEVDPRIQGELEKLNQSTDDINRRETELEDARQKFRSVLVEATVKLDELVKKIGKA 94
L E+ E + Q EL++L +++ E+ R K+ + ++ T +L+E KK+
Sbjct: 1392 LREQHEEEAEAQAELQRL------LSKANAEVAQWRSKYEADAIQRTEELEEAKKKLALR 1445
Query: 95 VEDSKPYWEA--------RRVARQAQLEAQKATQDFQRATEVLRAAKETISLAEQRLLED 146
+++++ EA + + Q E++ T + +RAT AA + +R LE+
Sbjct: 1446 LQEAEEGVEAANAKCSSLEKAKLRLQTESEDVTLELERATSA-AAALDKKQRHLERALEE 1504
Query: 147 DKRQFDSAWQEMLNHATQRVMEAEQTKT-RSELVHKETAARYNAAMGRMRQLEKKLKRAI 205
+RQ + +E+ A QR T+ R H+E A+ +++ K L+ I
Sbjct: 1505 RRRQEEEMQREL--EAAQRESRGLGTELFRLRHGHEEAL----EALETLKRENKNLQEEI 1558
Query: 206 NKSKPYFELKAKYYVQLEQLKKTVD----DLQAKLTLAKGEYKM 245
+ L K +LE+ KK ++ ++QA L A+G ++
Sbjct: 1559 SDLTDQVSLSGKSIQELEKTKKALEGEKSEIQAALEEAEGALEL 1602
Score = 48.1 bits (113), Expect = 2e-05
Identities = 55/283 (19%), Positives = 121/283 (42%), Gaps = 40/283 (14%)
Query: 10 SEEPAEILPPARDEEEEEEEGMEQGLEEEEEVDP-------RIQGELEKLNQSTDDINRR 62
+EE +L ++ + E + + + + LE+EEEV+ +++ E +L + DD+
Sbjct: 950 AEERCHLLIKSKVQLEGKVKELSERLEDEEEVNADLAARRRKLEDECTELKKDIDDLKLT 1009
Query: 63 ETELEDARQKFRSVLVEATVKLDELVKKIGKAVEDSKPYWEARRVA-------------- 108
+ E +Q + + T ++ L + + + ++ K EA + A
Sbjct: 1010 LAKAEKEKQATENKVKNLTEEMAALDESVARLTKEKKALQEAHQQALGDLQAEEDRVSAL 1069
Query: 109 RQAQLEAQKATQDFQRATEVLRAAKETISLAEQRLLEDDKRQFDSAWQEMLNHATQRVME 168
+A+L ++ +D + + E + + A+++L D K QE + A Q +
Sbjct: 1070 TKAKLRLEQQVEDLECSLEQEKKLRMDTERAKRKLEGDLK-----LTQESVADAAQDKQQ 1124
Query: 169 AEQTKTRSELVHKETAARYNAAMGRMRQLEKKLKRAINKSKPYFELKAKYYVQLEQLKKT 228
E+ + + + + R Q++KK+K EL+A+ E+L++
Sbjct: 1125 LEEKLKKKDSELSQLSLRVEDEQLLGAQMQKKIK----------ELQAR----AEELEEE 1170
Query: 229 VDDLQAKLTLAKGEYKMALKNLEMISDEIHERRRSSAMGPRGC 271
++ +A + + A + LE +S+ + E +SA GC
Sbjct: 1171 LEAERAARARVEKQRAEAARELEELSERLEEAGGASAGQREGC 1213
Score = 40.0 bits (92), Expect = 0.004
Identities = 49/204 (24%), Positives = 87/204 (42%), Gaps = 26/204 (12%)
Query: 44 RIQGELEKLNQSTDDINRRETELEDARQKFRSVLVEATVKLDELVKKIGKAVEDSKPYWE 103
+++G+L L R+ TE + A + ++ L E DE +++ + + E
Sbjct: 1666 KMEGDLNDLELQLGHATRQATEAQAATRLMQAQLKEEQAGRDE-EQRLAAELHEQAQALE 1724
Query: 104 ARRVARQAQLEAQKATQDFQRATEVLRAAKETISLAEQRLLEDDKRQFDSAWQEMLNHAT 163
R A+LE +A L + + LAEQ LLE +R L H+
Sbjct: 1725 RRASLLAAELEELRAA---------LEQGERSRRLAEQELLEATERL-------NLLHSQ 1768
Query: 164 QRVMEAEQTKTRSELVHKETAARYNAAMGRMRQLEKKLKRAINKSKPYFELKAKYY---V 220
+ ++ K ++L + + A R+ E+K K+AI + E K
Sbjct: 1769 NTGLLNQKKKLEADLA--QLSGEVEEAAQERREAEEKAKKAITDAAMMAEELKKEQDTSA 1826
Query: 221 QLEQLKKTVD----DLQAKLTLAK 240
LE++KKT++ +LQA+L A+
Sbjct: 1827 HLERMKKTLEQTVRELQARLEEAE 1850
Score = 38.9 bits (89), Expect = 0.010
Identities = 64/288 (22%), Positives = 117/288 (40%), Gaps = 37/288 (12%)
Query: 2 DAALKRSRSEEPAEILPPARDEEEEEEEGMEQGLEEEEEVDPRIQGELEKLNQSTDDINR 61
D L+ R+ A L ++++ +E+ LEE + +Q ELE + + +
Sbjct: 1476 DVTLELERATSAAAAL-------DKKQRHLERALEERRRQEEEMQRELEAAQRESRGLGT 1528
Query: 62 RETEL----EDARQKFRSV------LVEATVKLDELVKKIGKAVEDSKPYWEARRVARQA 111
L E+A + ++ L E L + V GK++++ + + ++
Sbjct: 1529 ELFRLRHGHEEALEALETLKRENKNLQEEISDLTDQVSLSGKSIQELE---KTKKALEGE 1585
Query: 112 QLEAQKATQDFQRATEVLRAAKETISLAEQRLLEDDKRQFDSAWQEM------LNHATQR 165
+ E Q A ++ + A E+ +ET +L Q L K + D E L QR
Sbjct: 1586 KSEIQAALEEAEGALEL----EETKTLRIQLELSQVKAEVDRKLAEKDEECANLRRNHQR 1641
Query: 166 VMEAEQTKTRSELVHKETAARYNAAM-GRMRQLEKKLKRAINKSKPYFELKAKYYVQLEQ 224
+E+ Q +E + A R M G + LE +L A ++ E +A + Q
Sbjct: 1642 AVESLQASLDAETRARNEALRLKKKMEGDLNDLELQLGHATRQAT---EAQAATRLMQAQ 1698
Query: 225 LK--KTVDDLQAKLTLAKGEYKMAL-KNLEMISDEIHERRRSSAMGPR 269
LK + D + +L E AL + +++ E+ E R + G R
Sbjct: 1699 LKEEQAGRDEEQRLAAELHEQAQALERRASLLAAELEELRAALEQGER 1746
>gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [Homo
sapiens]
Length = 1937
Score = 52.8 bits (125), Expect = 7e-07
Identities = 60/228 (26%), Positives = 105/228 (46%), Gaps = 22/228 (9%)
Query: 31 MEQGLEEEEEVDPRIQGELEKLNQSTDDINRRETELEDARQKFRSVLVEATVKLDELVKK 90
+ + EEE+E +Q L K N +E+ R K+ + ++ T +L+E KK
Sbjct: 1346 LREQYEEEQEGKAELQRALSKAN----------SEVAQWRTKYETDAIQRTEELEEAKKK 1395
Query: 91 IGKAVEDSKPYWEARRVARQAQLEAQKATQDFQRATEVLRAAKETISLAEQRLLEDDKRQ 150
+ + +++++ + EA A+ A LE K Q Q E L E S A L+ +R
Sbjct: 1396 LAQRLQEAEEHVEAVN-AKCASLE--KTKQRLQNEVEDLMLDVER-SNAACAALDKKQRN 1451
Query: 151 FD---SAWQEMLNHATQRVMEAEQTKTRS---ELVH-KETAARYNAAMGRMRQLEKKLKR 203
FD S W++ TQ +EA Q ++RS EL K + +R+ K L++
Sbjct: 1452 FDKVLSEWKQKYEE-TQAELEASQKESRSLSTELFKVKNVYEESLDQLETLRRENKNLQQ 1510
Query: 204 AINKSKPYFELKAKYYVQLEQLKKTVDDLQAKLTLAKGEYKMALKNLE 251
I+ K +LE++KK V+ + ++ A E + +L++ E
Sbjct: 1511 EISDLTEQIAEGGKQIHELEKIKKQVEQEKCEIQAALEEAEASLEHEE 1558
Score = 40.8 bits (94), Expect = 0.003
Identities = 50/246 (20%), Positives = 103/246 (41%), Gaps = 19/246 (7%)
Query: 24 EEEEEEGMEQGLEEEEEVDPRIQGELEKLNQSTDDINRRETELEDARQKFRSVLVEATVK 83
+EEE++ + L + R+Q E + ++ D+ + ++L ++Q + E +
Sbjct: 1265 KEEEQQRLINDLTAQRA---RLQTEAGEYSRQLDEKDALVSQLSRSKQASTQQIEELKHQ 1321
Query: 84 LDELVKK---IGKAVEDSKPYWEARRVA----RQAQLEAQKATQDFQRATEVLRAAKETI 136
L+E K + A++ S+ + R ++ + E Q+A R ET
Sbjct: 1322 LEEETKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETD 1381
Query: 137 SLAEQRLLEDDKRQFDSAWQEMLNH---ATQRVMEAEQTKTRSELVHKE---TAARYNAA 190
++ LE+ K++ QE H + E+TK R + ++ R NAA
Sbjct: 1382 AIQRTEELEEAKKKLAQRLQEAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERSNAA 1441
Query: 191 MGRMRQLEKKLKRAINKSKPYFELKAKYYVQLEQLKKTVDDLQAKLTLAKGEYKMALKNL 250
+ + ++ + +++ K +E + +LE +K L +L K Y+ +L L
Sbjct: 1442 CAALDKKQRNFDKVLSEWKQKYE---ETQAELEASQKESRSLSTELFKVKNVYEESLDQL 1498
Query: 251 EMISDE 256
E + E
Sbjct: 1499 ETLRRE 1504
Score = 38.5 bits (88), Expect = 0.013
Identities = 54/272 (19%), Positives = 113/272 (41%), Gaps = 42/272 (15%)
Query: 10 SEEPAEILPPARDEEEEEEEGMEQGLEEEEEVDP-------RIQGELEKLNQSTDDIN-- 60
+EE E L + + E + + + + EEEEE++ +++ E +L + DD+
Sbjct: 904 AEERCEQLIKNKIQLEAKIKEVTERAEEEEEINAELTAKKRKLEDECSELKKDIDDLELT 963
Query: 61 --RRETELEDARQKFRSVLVEATVKLDELVKKIGK-----------AVEDSKPYWEARRV 107
+ E E K ++ L E LDE + K+ K ++D + + +
Sbjct: 964 LAKVEKEKHATENKVKN-LTEEMAGLDETIAKLSKEKKALQETHQQTLDDLQAEEDKVNI 1022
Query: 108 ARQAQLEAQKATQDFQRATEVLRAAKETISLAEQRLLEDDKRQFDSAWQEMLNHATQRVM 167
+A+ + ++ D + + E + + + A +R LE D + + +M N Q
Sbjct: 1023 LTKAKTKLEQQVDDLEGSLEQEKKLRMDLERA-KRKLEGDLKLAQESTMDMENDKQQ--- 1078
Query: 168 EAEQTKTRSELVHKETAARYNAAMGRMRQLEKKLKRAINKSKPYFELKAKYYVQLEQLKK 227
++ + E ++ QL+KK+K EL+A+ +E+L +
Sbjct: 1079 -LDEKLEKKEFEISNLISKIEDEQAVEIQLQKKIK----------ELQAR----IEELGE 1123
Query: 228 TVDDLQAKLTLAKGEYKMALKNLEMISDEIHE 259
++ +A A+ + + LE IS+ + E
Sbjct: 1124 EIEAERASRAKAEKQRSDLSRELEEISERLEE 1155
Score = 38.1 bits (87), Expect = 0.017
Identities = 57/266 (21%), Positives = 105/266 (39%), Gaps = 27/266 (10%)
Query: 2 DAALKRSRSEEPAEILPPARDEEEEEEEGMEQGLEEEEEVDPRIQGELEKLNQSTDDINR 61
DA + EE + L E EE E + E+ R+Q E+E L + N
Sbjct: 1381 DAIQRTEELEEAKKKLAQRLQEAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERSNA 1440
Query: 62 RETELEDARQKFRSVLVEATVKLDELVKKIGKAVEDSKPYWEARRVARQAQLEAQKATQD 121
L+ ++ F VL E K +E ++ + ++S R E K
Sbjct: 1441 ACAALDKKQRNFDKVLSEWKQKYEETQAELEASQKES----------RSLSTELFKVKNV 1490
Query: 122 FQRATEVLRAAKETISLAEQRLLEDDKRQFDSAWQEMLNHATQRVMEAEQTKTRSELVHK 181
++ + + L ET+ + L +Q S E + +++ E E+ K + E
Sbjct: 1491 YEESLDQL----ETLRRENKNL-----QQEISDLTEQIAEGGKQIHELEKIKKQVEQEKC 1541
Query: 182 ETAARYNAAMGRMRQLEKKLKR---AINKSKPYFELK-AKYYVQLEQLK----KTVDDLQ 233
E A A + E K+ R +N+ K + K A+ +++QLK + V+ +Q
Sbjct: 1542 EIQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHTRVVETMQ 1601
Query: 234 AKLTLAKGEYKMALKNLEMISDEIHE 259
+ L AL+ + + +++E
Sbjct: 1602 STLDAEIRSRNDALRVKKKMEGDLNE 1627
Score = 33.5 bits (75), Expect = 0.41
Identities = 51/263 (19%), Positives = 112/263 (42%), Gaps = 23/263 (8%)
Query: 1 MDAALKRSRSEEPAEILPPARDEEEEEEEGMEQGLEEEEEVDPRIQGELEKLNQSTDDIN 60
++A+ K SRS L ++ EE + +E E + + I E++ + I+
Sbjct: 1470 LEASQKESRSLSTE--LFKVKNVYEESLDQLETLRRENKNLQQEISDLTEQIAEGGKQIH 1527
Query: 61 RRET---ELEDARQKFRSVLVEATVKLDELVKKIGKA-VEDSKPYWEARRVARQAQLEAQ 116
E ++E + + ++ L EA L+ KI + +E ++ E R + E
Sbjct: 1528 ELEKIKKQVEQEKCEIQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEID 1587
Query: 117 KATQDFQRATEVLRAAKETISLAEQRLLEDD---KRQFDSAWQEM---LNHATQRVMEAE 170
+ ++ R E +++ + AE R D K++ + EM LNHA + E+
Sbjct: 1588 QLKRNHTRVVETMQSTLD----AEIRSRNDALRVKKKMEGDLNEMEIQLNHANRLAAESL 1643
Query: 171 QTKTRSELVHKETAARYNAAMGRMRQLEKKLKRAINKSKPYFELKAKYYVQLEQLKKTVD 230
+ ++ + KET + A+ L+++L ++ ++E+L T++
Sbjct: 1644 RNYRNTQGILKETQLHLDDALRGQEDLKEQLAIVERRAN-------LLQAEIEELWATLE 1696
Query: 231 DLQAKLTLAKGEYKMALKNLEMI 253
+ +A+ E A + ++++
Sbjct: 1697 QTERSRKIAEQELLDASERVQLL 1719
>gi|87298937 centrosomal protein 110kDa [Homo sapiens]
Length = 2325
Score = 52.8 bits (125), Expect = 7e-07
Identities = 69/291 (23%), Positives = 126/291 (43%), Gaps = 56/291 (19%)
Query: 23 EEEEEEEGMEQGL------EEEEEVDPRIQGELEKLNQSTDDINRRETELEDARQKFRSV 76
E E+E + ++ L EE+E+ + + +L+ L DD N + +L+D + V
Sbjct: 743 ELEKERQALKNALGKAQFSEEKEQENSELHAKLKHLQ---DDNNLLKQQLKDFQNHLNHV 799
Query: 77 L------VEATVKLDELVKKI----------------GKAVED---------SKPYWEAR 105
+ E ++DEL +K+ GK++ D ++ WE
Sbjct: 800 VDGLVRPEEVAARVDELRRKLKLGTGEMNIHSPSDVLGKSLADLQKQFSEILARSKWERD 859
Query: 106 RVARQAQLEAQKATQDFQRATEVLRAAKETISLAEQRLLED----DKRQFDSAWQEMLN- 160
+AQ+ +K ++ E L +E A +R LE DKRQ ++ Q+M N
Sbjct: 860 ----EAQVRERKLQEEMALQQEKLATGQEEFRQACERALEARMNFDKRQHEARIQQMENE 915
Query: 161 --HATQRVMEAEQTKTRSELVHKETAARYNAAMGRMRQLEKKLKRAINKSKPYFELKAKY 218
+ + + E+ + ++L +E + ++R+LEKK K KS+ K
Sbjct: 916 IHYLQENLKSMEEIQGLTDLQLQEADEEKERILAQLRELEKKKKLEDAKSQEQVFGLDKE 975
Query: 219 YVQLEQLKKTVDDL-QAKLTLAKGEYK----MALKNLEMISDEIHERRRSS 264
+L++ T D L A+LT+AK + K +K + ++E+ E R S
Sbjct: 976 LKKLKKAVATSDKLATAELTIAKDQLKSLHGTVMKINQERAEELQEAERFS 1026
Score = 42.0 bits (97), Expect = 0.001
Identities = 59/261 (22%), Positives = 113/261 (43%), Gaps = 39/261 (14%)
Query: 26 EEEEGMEQGLEEEEEVDPR-IQGELEKLNQST----DDINRRETELEDARQKFRSVLVEA 80
EE MEQ E+ E++ R +Q EL++LN+ +DI+ + +L++ R+ S+ E
Sbjct: 1814 EENSKMEQSNLEKLELNVRKLQQELDQLNRDKLSLHNDISAMQQQLQEKREAVNSLQEEL 1873
Query: 81 TVKLDELVKKIGKAVEDSKPYWEARRVARQAQLEAQKATQDFQRATEVLRAAKETISLAE 140
D L A +D + + V Q QK ++ E + +ET
Sbjct: 1874 ANVQDHL----NLAKQDLLHTTKHQDVLLSEQTRLQKDISEWANRFEDCQKEEETKQQQL 1929
Query: 141 QRLL-EDDKRQFDSAWQEMLNHATQRVMEAEQTK------TRSELVHK------------ 181
Q L E ++ + QEM+ Q+ E+E++K T E H+
Sbjct: 1930 QVLQNEIEENKLKLVQQEMMFQRLQKERESEESKLETSKVTLKEQQHQLEKELTDQKSKL 1989
Query: 182 -ETAARYNAAMGRMRQLEKK------LKRAINKSKPYFELKAKYYV----QLEQLKKTVD 230
+ ++ AA R+R L+++ L++ ++++K + + V +L L+K D
Sbjct: 1990 DQVLSKVLAAEERVRTLQEEERWCESLEKTLSQTKRQLSEREQQLVEKSGELLALQKEAD 2049
Query: 231 DLQAKLTLAKGEYKMALKNLE 251
++A +L + ++ K E
Sbjct: 2050 SMRADFSLLRNQFLTERKKAE 2070
Score = 37.7 bits (86), Expect = 0.022
Identities = 60/276 (21%), Positives = 117/276 (42%), Gaps = 31/276 (11%)
Query: 6 KRSRSEEPAEILPPARDEEEEEEEGMEQGLEEEEEVDPRIQGELEKLNQSTDDINRRETE 65
+RS E +L A E +E + +E+ + + L + +++ RR E
Sbjct: 1431 RRSELREADRLLAEAESELSCTKEKTKNAVEKFTDA----KRSLLQTESDAEELERRAQE 1486
Query: 66 ----LEDARQKFRSVLVEAT------VKLDELVKKIGK--AVEDSKPYWEARRVARQAQL 113
L A Q+ RS+ +A +K +E++K+I K A +DS +++ + +
Sbjct: 1487 TAVNLVKADQQLRSLQADAKDLEQHKIKQEEILKEINKIVAAKDSDFQCLSKKKEKLTE- 1545
Query: 114 EAQKATQDFQRAT-------EVLRAAKETISLAEQRLLEDDKRQFDSAWQEMLNHATQRV 166
E QK +D + A +VL+ + E + A++ LE K Q S QEM Q
Sbjct: 1546 ELQKLQKDIEMAERNEDHHLQVLKES-EVLLQAKRAELEKLKSQVTSQQQEMAVLDRQLG 1604
Query: 167 MEAEQTKT-RSELVHKETAARYNAAMGRMRQLEKKLKRAINKSKPYFELKAKYYVQLEQL 225
+ E+ + +V + + +G EK N + L + Q +L
Sbjct: 1605 HKKEELHLLQGSMVQAKADLQEALRLGETEVTEK-----CNHIREVKSLLEELSFQKGEL 1659
Query: 226 KKTVDDLQAKLTLAKGEYKMALKNLEMISDEIHERR 261
+ + + +LTL K E + +NL+++ ++ + +
Sbjct: 1660 NVQISERKTQLTLIKQEIEKEEENLQVVLRQMSKHK 1695
Score = 36.6 bits (83), Expect = 0.048
Identities = 48/247 (19%), Positives = 111/247 (44%), Gaps = 22/247 (8%)
Query: 23 EEEEEEEGMEQGLEEEEEVDPRIQG-----ELEKLNQSTDDINRRETELEDARQKFRSVL 77
E EE +++ ++++ +D ++ E+EK + +DI +E K RS L
Sbjct: 1376 EVEELHRTVQKRQQQKDFIDGNVESLMTELEIEKSLKHHEDIVDEIECIEKTLLKRRSEL 1435
Query: 78 VEATVKLDELVKKIGKAVEDSKPYWEARRVARQAQLEAQKATQDFQR-----ATEVLRAA 132
EA L E ++ E +K E A+++ L+ + ++ +R A +++A
Sbjct: 1436 READRLLAEAESELSCTKEKTKNAVEKFTDAKRSLLQTESDAEELERRAQETAVNLVKAD 1495
Query: 133 KETISL-AEQRLLEDDKRQFDSAWQEMLNHATQRVMEAEQTKTRSELVHKETAARYNAAM 191
++ SL A+ + LE K + QE + +++ A+ + + KE
Sbjct: 1496 QQLRSLQADAKDLEQHKIK-----QEEILKEINKIVAAKDSDFQCLSKKKEKLTE----- 1545
Query: 192 GRMRQLEKKLKRAINKSKPYFELKAKYYVQLEQLKKTVDDLQAKLTLAKGEYKMALKNLE 251
+++L+K ++ A + ++ + V L+ + ++ L++++T + E + + L
Sbjct: 1546 -ELQKLQKDIEMAERNEDHHLQVLKESEVLLQAKRAELEKLKSQVTSQQQEMAVLDRQLG 1604
Query: 252 MISDEIH 258
+E+H
Sbjct: 1605 HKKEELH 1611
Score = 33.9 bits (76), Expect = 0.31
Identities = 42/184 (22%), Positives = 76/184 (41%), Gaps = 20/184 (10%)
Query: 25 EEEEEGMEQGLEEEEEVDPRIQGELEKLNQSTDDINRRETELEDARQKFRSVLVEATVKL 84
E E +++ L+ EE+ +L++ ++ + I + ELE ++ + E L
Sbjct: 913 ENEIHYLQENLKSMEEIQGLTDLQLQEADEEKERILAQLRELEKKKKLEDAKSQEQVFGL 972
Query: 85 DELVKKIGKAVEDSKPYWEARRVARQAQLEA---------QKATQDFQRATEVLRAAKE- 134
D+ +KK+ KAV S A + QL++ Q+ ++ Q A R A +
Sbjct: 973 DKELKKLKKAVATSDKLATAELTIAKDQLKSLHGTVMKINQERAEELQEAERFSRKAAQA 1032
Query: 135 ----TISLAEQRLLEDDKRQFDSAWQEMLNH------ATQRVMEAEQTKTRSELVHKETA 184
T + AE LL++ RQ ++ + A +V+E E+ E E A
Sbjct: 1033 ARDLTRAEAEIELLQNLLRQKGEQFRLEMEKTGVGTGANSQVLEIEKLNETMERQRTEIA 1092
Query: 185 ARYN 188
N
Sbjct: 1093 RLQN 1096
>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
Length = 1960
Score = 52.4 bits (124), Expect = 9e-07
Identities = 55/238 (23%), Positives = 116/238 (48%), Gaps = 21/238 (8%)
Query: 28 EEGMEQGLEEEEEVDPRIQGELEKLNQSTDDINRRETELEDARQKFRSVLVEATVKLDEL 87
EE MEQ E E ++ + + E+E L S DD+ + ELE +++ + E +L+EL
Sbjct: 1486 EEAMEQKAELER-LNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEEL 1544
Query: 88 VKKIGKAVEDSKPYWEARRVARQAQLEAQKATQDFQRATEVLRAAKETISLAEQRLLEDD 147
++ +A ED+K E A +AQ E +D Q + + ++ + + LED+
Sbjct: 1545 EDEL-QATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAE--LEDE 1601
Query: 148 KRQFDSAWQEMLNHATQRV-MEAEQTKTRSELVHKETAARYNAAMGRMRQLEKKLKRAIN 206
++Q + M A +++ M+ + + + +K + A+ ++R+L+ ++K +
Sbjct: 1602 RKQ-----RSMAVAARKKLEMDLKDLEAHIDSANKNR----DEAIKQLRKLQAQMKDCMR 1652
Query: 207 K------SKPYFELKAK-YYVQLEQLKKTVDDLQAKLTLAKGEYKMALKNLEMISDEI 257
+ S+ +AK +L+ ++ + LQ +L A+ + A + + ++DEI
Sbjct: 1653 ELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEI 1710
Score = 52.0 bits (123), Expect = 1e-06
Identities = 56/255 (21%), Positives = 112/255 (43%), Gaps = 15/255 (5%)
Query: 8 SRSEEPAEILPPARDEEEEEEEGMEQGLEEEEEVDPRIQGELEKLNQSTDDINRRETELE 67
+ +EE L + E EE +E +EEEEE +Q E +K+ Q+ ++ + E E
Sbjct: 897 AEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEE 956
Query: 68 DARQKFRSVLVEATVKLDELVKKIGKAVEDSKPYWEARRVARQAQLEAQKATQDFQRATE 127
ARQK + V KL +L ++ +ED + ++A++ +L + + TE
Sbjct: 957 SARQKLQLEKVTTEAKLKKLEEE-QIILED-----QNCKLAKEKKLLEDRIAEFTTNLTE 1010
Query: 128 VLRAAKETISLAEQRL-----LEDDKRQFDSAWQEMLNHATQRVMEAEQTKTRSELVHKE 182
+K L + LE+ R+ + QE+ T+R +E + T ++ E
Sbjct: 1011 EEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQEL--EKTRRKLEGDSTDLSDQIA--E 1066
Query: 183 TAARYNAAMGRMRQLEKKLKRAINKSKPYFELKAKYYVQLEQLKKTVDDLQAKLTLAKGE 242
A+ ++ + E++L+ A+ + + K ++ +L+ + +LQ L +
Sbjct: 1067 LQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQISELQEDLESERAS 1126
Query: 243 YKMALKNLEMISDEI 257
A K + +E+
Sbjct: 1127 RNKAEKQKRDLGEEL 1141
Score = 46.6 bits (109), Expect = 5e-05
Identities = 50/195 (25%), Positives = 85/195 (43%), Gaps = 16/195 (8%)
Query: 31 MEQGLEEEEEVDPRIQGELEKLNQSTDDINR-------RETELEDARQKFRSVLVEATVK 83
+E+ LEEE+ I L+K N D IN + E+ARQ+ E VK
Sbjct: 1734 LEEELEEEQGNTELINDRLKKANLQIDQINTDLNLERSHAQKNENARQQLERQNKELKVK 1793
Query: 84 LDELVKKIGKAVEDSKPYWEARRVARQAQLEAQKATQDFQRATEVLRAAKETISLAEQRL 143
L E+ + + S EA+ AQLE Q + +R + + L + L
Sbjct: 1794 LQEMEGTVKSKYKASITALEAKI----AQLEEQLDNETKERQAACKQVRRTEKKLKDVLL 1849
Query: 144 LEDDKRQFDSAWQEMLNHATQRVMEAEQTKTRSELVHKETAARYNAAMGRM-RQLEKKLK 202
DD+R+ +++ + A+ R+ + ++ +E E A R NA+ ++ R+LE +
Sbjct: 1850 QVDDERRNAEQYKDQADKASTRLKQLKRQLEEAE----EEAQRANASRRKLQRELEDATE 1905
Query: 203 RAINKSKPYFELKAK 217
A ++ LK K
Sbjct: 1906 TADAMNREVSSLKNK 1920
Score = 45.4 bits (106), Expect = 1e-04
Identities = 54/266 (20%), Positives = 109/266 (40%), Gaps = 20/266 (7%)
Query: 1 MDAALKRSRSEEPAEILPPARDEEEEEEEGMEQGLEEEEEVDPRIQGELEKLNQSTDDIN 60
M+A L+ R + + AR + E + + +E ++ + +L KL D
Sbjct: 1594 MEAELEDERKQRSMAVA--ARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCM 1651
Query: 61 RRETELEDARQKFRSVLVEATVKLDELVKKIGKAVEDSKPYWEARRVARQAQLEAQKATQ 120
R EL+D R +L +A +L + ++ + A R RQAQ E +
Sbjct: 1652 R---ELDDTRASREEILAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELAD 1708
Query: 121 DFQRATEVLRAAKETISLAEQRLLE------DDKRQFDSAWQEMLNHATQRV-MEAEQTK 173
+ + + K ++L E+R LE +++ + + E++N ++ ++ +Q
Sbjct: 1709 EIANS-----SGKGALALEEKRRLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQIN 1763
Query: 174 TRSELVHKETAARYNAAMGRMRQLEKKLKRAINKSKPYFELKAKYYVQLEQLKKTVDDLQ 233
T L NA RQ K+LK + + + +K+KY + L+ + L+
Sbjct: 1764 TDLNLERSHAQKNENARQQLERQ-NKELKVKLQEMEG--TVKSKYKASITALEAKIAQLE 1820
Query: 234 AKLTLAKGEYKMALKNLEMISDEIHE 259
+L E + A K + ++ +
Sbjct: 1821 EQLDNETKERQAACKQVRRTEKKLKD 1846
Score = 42.4 bits (98), Expect = 9e-04
Identities = 66/296 (22%), Positives = 119/296 (40%), Gaps = 51/296 (17%)
Query: 35 LEEEEEVDPRIQGELEKLNQSTDDINRRETELEDARQKFRSVLVEATVKLD-------EL 87
LE EEV ++Q +LE L+Q ++ +LE + + + L + V LD L
Sbjct: 1380 LETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNL 1439
Query: 88 VKKIGK---------------AVEDSKPYWEAR-------------RVARQAQLEAQKAT 119
KK K A E + EAR A + + E ++
Sbjct: 1440 EKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKAELERLN 1499
Query: 120 QDFQRATEVLRAAKETISLAEQRLLEDDKRQFDSAWQEM---LNHATQRVMEAEQTKTRS 176
+ F+ E L ++K+ + + LE KR + +EM L + E K R
Sbjct: 1500 KQFRTEMEDLMSSKDDVGKSVHE-LEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRL 1558
Query: 177 ELVHKETAARYNAAM-GRMRQLEKKLKRAINKSKPYFELKAKYYVQLEQLKKTVDDLQAK 235
E+ + A++ + GR Q E+K K+ + + + E++A +LE +K ++
Sbjct: 1559 EVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVR---EMEA----ELEDERKQ----RSM 1607
Query: 236 LTLAKGEYKMALKNLEMISDEIHERRRSSAMGPRGCGVGAEGSSTSVEDLPGSKPE 291
A+ + +M LK+LE D ++ R + R + ++D S+ E
Sbjct: 1608 AVAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREE 1663
Score = 38.9 bits (89), Expect = 0.010
Identities = 58/299 (19%), Positives = 127/299 (42%), Gaps = 39/299 (13%)
Query: 2 DAALKRSRSEEPAEILPPARDEEEEEEEGMEQGLEEEEEVDPRIQ-------GELEKLNQ 54
D + EE + L + + ++ + +E+ LEEEE ++Q +L+KL +
Sbjct: 919 DLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEE 978
Query: 55 STDDINRRETELEDARQKFRSVLVEATVKLDELVKKIGKAVEDSKPYWEARRVARQAQL- 113
+ + +L ++ + E T L E +K K++ K EA + +L
Sbjct: 979 EQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEK-SKSLAKLKNKHEAMITDLEERLR 1037
Query: 114 EAQKATQDFQRATEVLRAAKETIS--LAE-QRLLEDDKRQFDSAWQEM------------ 158
+K Q+ ++ L +S +AE Q + + K Q +E+
Sbjct: 1038 REEKQRQELEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAA 1097
Query: 159 -LNHATQRVMEAE------QTKTRSELVHKETAARYNAAMG-RMRQLEKKLKRAINKSKP 210
N A +++ E E Q SE + A + +G + L+ +L+ ++ +
Sbjct: 1098 QKNMALKKIRELESQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAA 1157
Query: 211 YFELKAKYYVQLEQLKKTVDD----LQAKLTLAKGEYKMALKNLEMISDEIHERRRSSA 265
EL++K ++ LKKT+++ +A++ + ++ A +E +++++ + +R A
Sbjct: 1158 QQELRSKREQEVNILKKTLEEEAKTHEAQIQEMRQKHSQA---VEELAEQLEQTKRVKA 1213
Score = 37.4 bits (85), Expect = 0.028
Identities = 57/276 (20%), Positives = 119/276 (43%), Gaps = 37/276 (13%)
Query: 25 EEEEEGMEQGLEEEEEVDPRIQGELEKLNQSTDDINRRETE-------LEDARQKFRSVL 77
E+E+ + LEEEEE ++ ++ L+ D+ ++ + E+ ++K + L
Sbjct: 1335 EDEKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDL 1394
Query: 78 ----------VEATVKLDELVKKIGKAVEDSKPYWEARRVA---------RQAQLEAQKA 118
V A KL++ ++ + ++D + +R + + QL A++
Sbjct: 1395 EGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEK 1454
Query: 119 TQDFQRATEVLRA-----AKETISLAEQRLLEDDKRQFDSAWQEMLNHATQRVME--AEQ 171
T + A E RA KET +L+ R LE+ Q A E LN + ME
Sbjct: 1455 TISAKYAEERDRAEAEAREKETKALSLARALEEAMEQ--KAELERLNKQFRTEMEDLMSS 1512
Query: 172 TKTRSELVHKETAARYNAAMGRMRQLEKKLKRAINKSKPYFELKAKYYVQLEQLKKTVD- 230
+ VH E A ++ +++ +L+ ++ + + K + V L+ +K +
Sbjct: 1513 KDDVGKSVH-ELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQAMKAQFER 1571
Query: 231 DLQAKLTLAKGEYKMALKNLEMISDEIHERRRSSAM 266
DLQ + ++ + K ++ + + E+ + R+ +M
Sbjct: 1572 DLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSM 1607
Score = 32.7 bits (73), Expect = 0.70
Identities = 44/242 (18%), Positives = 92/242 (38%), Gaps = 32/242 (13%)
Query: 8 SRSEEPAEILPPARDEEEEEEEGMEQGLEEEEEVDPRIQGELEKLNQSTDDINRRETELE 67
S+S+ + L E + + ++ L+EE + +L+++ + + E E
Sbjct: 1290 SQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEE 1349
Query: 68 DARQKFRSVLVEATVKLDELVKKIGKAVEDSKPYWE-ARRVARQAQLEAQKATQDFQRAT 126
+A+ + ++ ++ KK +EDS E A V R+ Q + + +Q +
Sbjct: 1350 EAKHNLEKQIATLHAQVADMKKK----MEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKV 1405
Query: 127 EVLRAAKETISLAEQRL----------------LEDDKRQFDSAWQEMLNHATQRVMEAE 170
++T + +Q L LE +++FD E E
Sbjct: 1406 AAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAE--EKTISAKYAEE 1463
Query: 171 QTKTRSELVHKETAARYNAAMGRMRQLEKKLKRAINKSKPYFELKAKYYVQLEQLKKTVD 230
+ + +E KET A L + L+ A+ + L ++ ++E L + D
Sbjct: 1464 RDRAEAEAREKETKA---------LSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKD 1514
Query: 231 DL 232
D+
Sbjct: 1515 DV 1516
>gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [Homo
sapiens]
Length = 1940
Score = 52.4 bits (124), Expect = 9e-07
Identities = 68/256 (26%), Positives = 106/256 (41%), Gaps = 24/256 (9%)
Query: 5 LKRSRSEE--PAEILPPARDEEEEEEEGMEQGLEEEEEVDPRIQGELEKLNQSTDDINRR 62
LKR EE L A + + + + EEE+E +Q L K N
Sbjct: 1316 LKRQLEEENKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKAN--------- 1366
Query: 63 ETELEDARQKFRSVLVEATVKLDELVKKIGKAVEDSKPYWEARRVARQAQLEAQKATQDF 122
+E+ R K+ + ++ T +L+E KK+ + ++DS+ EA A+ A LE K Q
Sbjct: 1367 -SEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDSEEQVEAVN-AKCASLE--KTKQRL 1422
Query: 123 QRATEVLRAAKETI-SLAEQRLLEDDKRQFDSAWQEMLNHATQRVMEAEQTKTRSELVHK 181
Q E L E SLA L+ +R FD E + E E + S +
Sbjct: 1423 QGEVEDLMVDVERANSLA--AALDKKQRNFDKVLAEWKTKCEESQAELEASLKESRSLST 1480
Query: 182 ETAARYNAAMGRMRQLE------KKLKRAINKSKPYFELKAKYYVQLEQLKKTVDDLQAK 235
E NA + QLE K L++ I K +LE+ +K ++ +A
Sbjct: 1481 ELFKLKNAYEEALDQLETVKRENKNLEQEIADLTEQIAENGKTIHELEKSRKQIELEKAD 1540
Query: 236 LTLAKGEYKMALKNLE 251
+ LA E + AL++ E
Sbjct: 1541 IQLALEEAEAALEHEE 1556
Score = 51.6 bits (122), Expect = 1e-06
Identities = 56/280 (20%), Positives = 117/280 (41%), Gaps = 27/280 (9%)
Query: 2 DAALKRSRSEEPAEILPPARDEEEEEEEGMEQGLEEEEEVDPRIQGELEKLNQSTDDINR 61
DA + EE + L + EE+ E + E+ R+QGE+E L + N
Sbjct: 1379 DAIQRTEELEEAKKKLAQRLQDSEEQVEAVNAKCASLEKTKQRLQGEVEDLMVDVERANS 1438
Query: 62 RETELEDARQKFRSVLVEATVKLDELVKKIGKAVEDSK-----------PYWEARRVARQ 110
L+ ++ F VL E K +E ++ ++++S+ Y EA
Sbjct: 1439 LAAALDKKQRNFDKVLAEWKTKCEESQAELEASLKESRSLSTELFKLKNAYEEALDQLET 1498
Query: 111 AQLEAQKATQDFQRATEVLRAAKETISLAE--QRLLEDDKRQFDSAWQE---MLNHATQR 165
+ E + Q+ TE + +TI E ++ +E +K A +E L H +
Sbjct: 1499 VKRENKNLEQEIADLTEQIAENGKTIHELEKSRKQIELEKADIQLALEEAEAALEHEEAK 1558
Query: 166 VM--EAEQTKTRSELVHKETAARYNAAMGRMRQLEKKLKRAINKSKPYFELKAKYYVQLE 223
++ + E T+ +SE+ K + QL++ +R + + + + + +
Sbjct: 1559 ILRIQLELTQVKSEIDRKIAEKD-----EEIEQLKRNYQRTVETMQSALDAEVRSRNEAI 1613
Query: 224 QLKKTVD----DLQAKLTLAKGEYKMALKNLEMISDEIHE 259
+LKK ++ +++ +L+ A + LK+L + ++ +
Sbjct: 1614 RLKKKMEGDLNEIEIQLSHANRQAAETLKHLRSVQGQLKD 1653
Score = 40.4 bits (93), Expect = 0.003
Identities = 58/274 (21%), Positives = 116/274 (42%), Gaps = 46/274 (16%)
Query: 10 SEEPAEILPPARDEEEEEEEGMEQGLEEEEEVDP-------RIQGELEKLNQSTDDINRR 62
+EE + L A+ + E + + + + E+EEE++ +++ E +L + DD+
Sbjct: 902 AEERCDQLIKAKFQLEAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELT 961
Query: 63 ETELEDARQKFRSVLVEATVKLDELVKKIGKAVEDSKPYWEARRVARQAQLEAQKATQDF 122
++E + + + T +L L + I K + K EA Q+A D
Sbjct: 962 LAKVEKEKHATENKVKNLTEELSGLDETIAKLTREKKALQEAH----------QQALDDL 1011
Query: 123 QRATEVLRAAKETISLAEQRLLEDDKRQFDSAWQEMLNHATQRVMEAEQTKTRSELVHKE 182
Q + + + +T S EQ+ +ED + L + ++ E+ K + E K
Sbjct: 1012 QAEEDKVNSLNKTKSKLEQQ-VED--------LESSLEQEKKLRVDLERNKRKLEGDLKL 1062
Query: 183 TAARYNAAMGRMRQLEKKLKRAINKSKPYFELKAKYYVQLE---QLKKTVDDLQAKL--- 236
+QL+++LK+ K Y +L++K + Q +K + +LQA++
Sbjct: 1063 AQESILDLENDKQQLDERLKK---KDFEYCQLQSKVEDEQTLGLQFQKKIKELQARIEEL 1119
Query: 237 ---------TLAKGEYKMA--LKNLEMISDEIHE 259
T AK E + + + LE +S+ + E
Sbjct: 1120 EEEIEAERATRAKTEKQRSDYARELEELSERLEE 1153
Score = 37.4 bits (85), Expect = 0.028
Identities = 58/266 (21%), Positives = 114/266 (42%), Gaps = 32/266 (12%)
Query: 14 AEILPPARDEEEE--EEEGMEQGLEEEEEVDPRIQGELEKLNQSTDDINRRETELEDARQ 71
AE L RD EE + E M L ++ + +L + D++ R + +LE +
Sbjct: 1170 AEFLKLRRDLEEATLQHEAMVAALRKKHA------DSVAELGEQIDNLQRVKQKLEKEKS 1223
Query: 72 KFRSVLVEATVKLDELVKKIGKAVEDSKPYWEARRVARQAQL-EAQKATQDFQRATEVLR 130
+F+ +++D+L + ++V SK E + QL EA+ ++ QR+ L
Sbjct: 1224 EFK-------LEIDDLSSSM-ESVSKSKANLEKICRTLEDQLSEARGKNEEIQRSLSELT 1275
Query: 131 AAKETISLAEQRLLE--DDKRQFDSAWQEMLNHATQRVME-----AEQTKTRSELVHKET 183
K + L ++K S TQ+ E E+ K ++ L H
Sbjct: 1276 TQKSRLQTEAGELSRQLEEKESIVSQLSRSKQAFTQQTEELKRQLEEENKAKNALAHALQ 1335
Query: 184 AARYNAAMGRMRQLEK-----KLKRAINK-SKPYFELKAKYYVQLEQLKKTVDDLQAKLT 237
++R++ + R + E+ +L+RA++K + + + KY Q + +++ + KL
Sbjct: 1336 SSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLA 1395
Query: 238 --LAKGEYKMALKNLEMISDEIHERR 261
L E ++ N + S E ++R
Sbjct: 1396 QRLQDSEEQVEAVNAKCASLEKTKQR 1421
>gi|4507651 tropomyosin 4 isoform 2 [Homo sapiens]
Length = 248
Score = 51.6 bits (122), Expect = 1e-06
Identities = 59/254 (23%), Positives = 116/254 (45%), Gaps = 32/254 (12%)
Query: 15 EILPPARDEEEEEEEGMEQGLEEEEEVDPRIQGELEKLNQST----DDINRRETELEDAR 70
+ L DE E+ +G+++ L+ E E + +G++ LN+ ++++R + L A
Sbjct: 15 QALQQQADEAEDRAQGLQRELDGERERREKAEGDVAALNRRIQLVEEELDRAQERLATAL 74
Query: 71 QKFRSVLVEATVKLDELVKKIGKAVEDSKPYWEARRVARQAQLE-----AQKATQDFQRA 125
QK L EA DE + + K +E+ E + ++ QL+ A++A + ++
Sbjct: 75 QK----LEEAEKAADESERGM-KVIENRAMKDEEKMEIQEMQLKEAKHIAEEADRKYEEV 129
Query: 126 TEVLRAAKETISLAEQRLLEDDKRQFDSAWQEMLNHATQRVMEAEQTKTRSELVHKETAA 185
L + + AE+R + + D +E L + T + E + + E
Sbjct: 130 ARKLVILEGELERAEERAEVSELKCGDL--EEELKNVTNNLKSLEAASEK----YSEKED 183
Query: 186 RYNAAMGRMRQLEKKLKRAINKSKPYFELKAKYYVQ-LEQLKKTVDDLQAKLTLAKGEYK 244
+Y ++ L KLK A E +A++ + + +L+KT+DDL+ KL AK E
Sbjct: 184 KYEE---EIKLLSDKLKEA--------ETRAEFAERTVAKLEKTIDDLEEKLAQAKEENV 232
Query: 245 MALKNLEMISDEIH 258
+ L+ +E++
Sbjct: 233 GLHQTLDQTLNELN 246
>gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens]
Length = 2003
Score = 51.6 bits (122), Expect = 1e-06
Identities = 66/281 (23%), Positives = 119/281 (42%), Gaps = 29/281 (10%)
Query: 7 RSRSEEPAEILPP---ARDEEEEEEEGMEQGLEEEEEVDPRIQGELEKLNQSTDDIN--- 60
R R EE A L AR E E + Q L E+ E R++ +L Q DD
Sbjct: 1402 RRRQEEEAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDL 1461
Query: 61 ----RRETELEDARQKFRSVLVEATVKLDELVKKIGKAVEDSKPYWEARRVARQAQLEA- 115
+ + LE ++KF +L E + V++ +A + + EAR ++ LE
Sbjct: 1462 EQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGRER-EARALSLTRALEEE 1520
Query: 116 QKATQDFQRATEVLRAAKETISLAEQRL------LEDDKRQFDSAWQEMLNHATQ---RV 166
Q+A ++ +R LRA E + ++ + LE R + A ++ T+ +
Sbjct: 1521 QEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDEL 1580
Query: 167 MEAEQTKTRSELV--------HKETAARYNAAMGRMRQLEKKLKRAINKSKPYFELKAKY 218
AE K R E+ ++ R A R RQL K+L+ A + + +
Sbjct: 1581 TAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLA 1640
Query: 219 YVQLEQLKKTVDDLQAKLTLAKGEYKMALKNLEMISDEIHE 259
++L+ +++L+A++ A + A+K L + ++ E
Sbjct: 1641 VAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKE 1681
Score = 45.4 bits (106), Expect = 1e-04
Identities = 64/302 (21%), Positives = 126/302 (41%), Gaps = 57/302 (18%)
Query: 32 EQGLEEEEEVDPRIQGELEKLNQSTDDINRRETELEDARQKFRSVLVEATVKLDE----- 86
E+G +E E++ R+ GE +L + + +R EL + L A + ++
Sbjct: 1072 EKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGAR 1131
Query: 87 --LVKKIGKA---VEDSKPYWEARRVARQA----------QLEAQKA----TQDFQRATE 127
L+K + +A + +++ E+ RVAR +LEA + T D A +
Sbjct: 1132 AQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQ 1191
Query: 128 VLRAAKETISLAEQRLLEDDKRQFDSAWQEMLN-----------------------HATQ 164
LR+ +E ++ LE++ R ++A QE+ T+
Sbjct: 1192 ELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTR 1251
Query: 165 RVMEAEQTKTRSELVHKETAARYNAAMGRMRQLEKKLKRAINKSKPYFELKAKYYVQLEQ 224
+EAE ++ R+EL +TA + R R+LE +L+ ++ +A+ +L++
Sbjct: 1252 LALEAEVSELRAELSSLQTARQEGEQ--RRRRLELQLQEVQGRAGDGERARAEAAEKLQR 1309
Query: 225 LKKTVDDLQAKLTLAKGEYKMALKNLEMISDEIH--------ERRRSSAMGPRGCGVGAE 276
+ ++++ L A+ + K L ++H E R A+G R + AE
Sbjct: 1310 AQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAE 1369
Query: 277 GS 278
+
Sbjct: 1370 AA 1371
Score = 45.1 bits (105), Expect = 1e-04
Identities = 55/259 (21%), Positives = 117/259 (45%), Gaps = 15/259 (5%)
Query: 8 SRSEEPAEILPPARDEEEEEEEGMEQGLEEEEEVDPRIQGELEKLNQSTDDINRRETELE 67
+ +EE L + E E +E + EEEE ++Q E ++L Q ++ E
Sbjct: 929 AEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEE 988
Query: 68 DARQKFRSVLVEATVKLDELVKKIGKAVEDSKPYWEARRVA--RQAQLEAQKATQDFQ-R 124
ARQK + V K+ + + + + + + R++ R A+ +Q A ++ + +
Sbjct: 989 GARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVK 1048
Query: 125 ATEVLRAAKE-TISLAEQRLLEDDKRQFDSAWQEMLNHATQRVMEAEQTKTRSELV-HKE 182
+ LR E TI+ E RL +++K + QE+ +R ++ E ++ + ++V ++
Sbjct: 1049 SLNKLRLKYEATIADMEDRLRKEEKGR-----QEL--EKLKRRLDGESSELQEQMVEQQQ 1101
Query: 183 TAARYNAAMGRMRQLEKKLKRAINKSKPYFELKAKYYVQLEQLKKTVDDLQAKLTLAKGE 242
A A +GR E++L+ A+ +++ +A+ L + + + + Q L +
Sbjct: 1102 RAEELRAQLGRK---EEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVA 1158
Query: 243 YKMALKNLEMISDEIHERR 261
A K + +E+ R
Sbjct: 1159 RTKAEKQRRDLGEELEALR 1177
Score = 42.7 bits (99), Expect = 7e-04
Identities = 48/208 (23%), Positives = 84/208 (40%), Gaps = 26/208 (12%)
Query: 25 EEEEEGMEQGLEEEEEVDPRIQGELEKLNQSTDDINRRETELEDARQKFRSVLVEATVKL 84
E E G+ + LEEE R EL+ + RR+ E A + A +
Sbjct: 1367 EAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREA 1426
Query: 85 DELVKKIGKAVEDSKPYWEARRVARQAQLEAQKATQDFQRATEVLRAAKETISLAEQRLL 144
+ L +++ + E R R+ Q E AT D ++ +++ L
Sbjct: 1427 EALTQRLAEKTETVD---RLERGRRRLQQELDDATMDLEQQRQLVST------------L 1471
Query: 145 EDDKRQFDSAWQEMLNHATQRVMEAEQTKTRSELVHKETAARYNAAMGRMRQLEKKLKRA 204
E +R+FD ++L V+ A + + R+E +E AR A+ R LE++ +
Sbjct: 1472 EKKQRKFD----QLLAEEKAAVLRAVEERERAEAEGREREAR---ALSLTRALEEEQEAR 1524
Query: 205 INKSKPYFELKAKYYVQLEQLKKTVDDL 232
+ L+A +LE L + DD+
Sbjct: 1525 EELERQNRALRA----ELEALLSSKDDV 1548
Score = 35.0 bits (79), Expect = 0.14
Identities = 70/313 (22%), Positives = 112/313 (35%), Gaps = 98/313 (31%)
Query: 10 SEEPAEILPPARDEEEEEEEGMEQ---------GLEEEEEVDPRIQ-------GELEKLN 53
+EE A +L + E E EG E+ LEEE+E ++ ELE L
Sbjct: 1483 AEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALL 1542
Query: 54 QSTDDINRRETELEDARQKFRSVLVEATVKLDELVKKIGKAVEDSKPYWEARRVARQAQL 113
S DD+ + ELE A + + ++ EL ++ A ED+K E A + Q
Sbjct: 1543 SSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDEL-TAAEDAKLRLEVTVQALKTQH 1601
Query: 114 EAQKATQDFQRATEVLRAAKE---------------TISLAEQRLLEDD----KRQFDSA 154
E +D + AK+ T+++A ++ LE + K Q SA
Sbjct: 1602 ERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASA 1661
Query: 155 ---------------------WQEMLNHATQRV---------------MEAEQTKTRSEL 178
W+E+ T R +EAE + + EL
Sbjct: 1662 GQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEEL 1721
Query: 179 VHKETAARY------------------NAAM--------GRMRQLEKKLKRAINKSKPYF 212
+ A R AA+ GR+ QLE++L+ + S+
Sbjct: 1722 AASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLN 1781
Query: 213 ELKAKYYVQLEQL 225
+ K +Q+E L
Sbjct: 1782 DRYRKLLLQVESL 1794
Score = 32.7 bits (73), Expect = 0.70
Identities = 53/264 (20%), Positives = 106/264 (40%), Gaps = 22/264 (8%)
Query: 3 AALKRSRSEEPAEILPPARDEEEEEEEGMEQGLEEEEEVDPRIQGELEKLNQSTDDINRR 62
AAL ++ + +E + + E++ + G EE E + ++ L+ N + ++R
Sbjct: 1143 AALAEAQEDLESERVARTKAEKQRRDLG-----EELEALRGELEDTLDSTNAQQELRSKR 1197
Query: 63 ETELEDARQKFRSVLVEATVKLDELVKKIGKAVEDSKPYWEARRVARQAQLEAQKATQDF 122
E E+ + ++ + EL ++ G+A+ + E AR+ + +K
Sbjct: 1198 EQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELA---EQLEQARRGKGAWEKTRLAL 1254
Query: 123 QRATEVLRAAKETISLAEQRLLEDDKRQFDSAWQEMLNHATQRVMEAEQTKTRSELVHKE 182
+ LRA ++ A Q E +R+ + QE+ R + E+ + + +
Sbjct: 1255 EAEVSELRAELSSLQTARQE-GEQRRRRLELQLQEVQG----RAGDGERARAEAAEKLQR 1309
Query: 183 TAARYNAAMGRMRQLEKKLKRAINKSKPYFELKAKYYVQLEQLKKTVDDLQAKLTLAKGE 242
A G + + E K I SK +A+ + E L+ ++ +AKL L
Sbjct: 1310 AQAELENVSGALNEAESK---TIRLSKELSSTEAQLHDAQELLQ---EETRAKLALGSRV 1363
Query: 243 YKM---ALKNLEMISDEIHERRRS 263
M A E + +E R R+
Sbjct: 1364 RAMEAEAAGLREQLEEEAAARERA 1387
Score = 29.3 bits (64), Expect = 7.7
Identities = 28/104 (26%), Positives = 50/104 (48%), Gaps = 15/104 (14%)
Query: 11 EEPAEILPPARDEEEEEE---EGMEQGLEEEEEVDPR-------IQGELEKLNQSTDDIN 60
EE + RD+ E+ + +++ LEE EE R +Q ELE + +S + +N
Sbjct: 1884 EEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMN 1943
Query: 61 RRETELEDARQK----FRSVLVEATVKLDELVKKIGKAVEDSKP 100
R T L + ++ F + V +L+E V +A E+++P
Sbjct: 1944 REVTTLRNRLRRGPLTFTTRTVRQVFRLEEGVASDEEA-EEAQP 1986
>gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens]
Length = 1995
Score = 51.6 bits (122), Expect = 1e-06
Identities = 66/281 (23%), Positives = 119/281 (42%), Gaps = 29/281 (10%)
Query: 7 RSRSEEPAEILPP---ARDEEEEEEEGMEQGLEEEEEVDPRIQGELEKLNQSTDDIN--- 60
R R EE A L AR E E + Q L E+ E R++ +L Q DD
Sbjct: 1394 RRRQEEEAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDL 1453
Query: 61 ----RRETELEDARQKFRSVLVEATVKLDELVKKIGKAVEDSKPYWEARRVARQAQLEA- 115
+ + LE ++KF +L E + V++ +A + + EAR ++ LE
Sbjct: 1454 EQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGRER-EARALSLTRALEEE 1512
Query: 116 QKATQDFQRATEVLRAAKETISLAEQRL------LEDDKRQFDSAWQEMLNHATQ---RV 166
Q+A ++ +R LRA E + ++ + LE R + A ++ T+ +
Sbjct: 1513 QEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDEL 1572
Query: 167 MEAEQTKTRSELV--------HKETAARYNAAMGRMRQLEKKLKRAINKSKPYFELKAKY 218
AE K R E+ ++ R A R RQL K+L+ A + + +
Sbjct: 1573 TAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLA 1632
Query: 219 YVQLEQLKKTVDDLQAKLTLAKGEYKMALKNLEMISDEIHE 259
++L+ +++L+A++ A + A+K L + ++ E
Sbjct: 1633 VAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKE 1673
Score = 45.4 bits (106), Expect = 1e-04
Identities = 64/302 (21%), Positives = 126/302 (41%), Gaps = 57/302 (18%)
Query: 32 EQGLEEEEEVDPRIQGELEKLNQSTDDINRRETELEDARQKFRSVLVEATVKLDE----- 86
E+G +E E++ R+ GE +L + + +R EL + L A + ++
Sbjct: 1064 EKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGAR 1123
Query: 87 --LVKKIGKA---VEDSKPYWEARRVARQA----------QLEAQKA----TQDFQRATE 127
L+K + +A + +++ E+ RVAR +LEA + T D A +
Sbjct: 1124 AQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQ 1183
Query: 128 VLRAAKETISLAEQRLLEDDKRQFDSAWQEMLN-----------------------HATQ 164
LR+ +E ++ LE++ R ++A QE+ T+
Sbjct: 1184 ELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTR 1243
Query: 165 RVMEAEQTKTRSELVHKETAARYNAAMGRMRQLEKKLKRAINKSKPYFELKAKYYVQLEQ 224
+EAE ++ R+EL +TA + R R+LE +L+ ++ +A+ +L++
Sbjct: 1244 LALEAEVSELRAELSSLQTARQEGEQ--RRRRLELQLQEVQGRAGDGERARAEAAEKLQR 1301
Query: 225 LKKTVDDLQAKLTLAKGEYKMALKNLEMISDEIH--------ERRRSSAMGPRGCGVGAE 276
+ ++++ L A+ + K L ++H E R A+G R + AE
Sbjct: 1302 AQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAE 1361
Query: 277 GS 278
+
Sbjct: 1362 AA 1363
Score = 45.1 bits (105), Expect = 1e-04
Identities = 55/259 (21%), Positives = 117/259 (45%), Gaps = 15/259 (5%)
Query: 8 SRSEEPAEILPPARDEEEEEEEGMEQGLEEEEEVDPRIQGELEKLNQSTDDINRRETELE 67
+ +EE L + E E +E + EEEE ++Q E ++L Q ++ E
Sbjct: 921 AEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEE 980
Query: 68 DARQKFRSVLVEATVKLDELVKKIGKAVEDSKPYWEARRVA--RQAQLEAQKATQDFQ-R 124
ARQK + V K+ + + + + + + R++ R A+ +Q A ++ + +
Sbjct: 981 GARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVK 1040
Query: 125 ATEVLRAAKE-TISLAEQRLLEDDKRQFDSAWQEMLNHATQRVMEAEQTKTRSELV-HKE 182
+ LR E TI+ E RL +++K + QE+ +R ++ E ++ + ++V ++
Sbjct: 1041 SLNKLRLKYEATIADMEDRLRKEEKGR-----QEL--EKLKRRLDGESSELQEQMVEQQQ 1093
Query: 183 TAARYNAAMGRMRQLEKKLKRAINKSKPYFELKAKYYVQLEQLKKTVDDLQAKLTLAKGE 242
A A +GR E++L+ A+ +++ +A+ L + + + + Q L +
Sbjct: 1094 RAEELRAQLGRK---EEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVA 1150
Query: 243 YKMALKNLEMISDEIHERR 261
A K + +E+ R
Sbjct: 1151 RTKAEKQRRDLGEELEALR 1169
Score = 42.7 bits (99), Expect = 7e-04
Identities = 48/208 (23%), Positives = 84/208 (40%), Gaps = 26/208 (12%)
Query: 25 EEEEEGMEQGLEEEEEVDPRIQGELEKLNQSTDDINRRETELEDARQKFRSVLVEATVKL 84
E E G+ + LEEE R EL+ + RR+ E A + A +
Sbjct: 1359 EAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREA 1418
Query: 85 DELVKKIGKAVEDSKPYWEARRVARQAQLEAQKATQDFQRATEVLRAAKETISLAEQRLL 144
+ L +++ + E R R+ Q E AT D ++ +++ L
Sbjct: 1419 EALTQRLAEKTETVD---RLERGRRRLQQELDDATMDLEQQRQLVST------------L 1463
Query: 145 EDDKRQFDSAWQEMLNHATQRVMEAEQTKTRSELVHKETAARYNAAMGRMRQLEKKLKRA 204
E +R+FD ++L V+ A + + R+E +E AR A+ R LE++ +
Sbjct: 1464 EKKQRKFD----QLLAEEKAAVLRAVEERERAEAEGREREAR---ALSLTRALEEEQEAR 1516
Query: 205 INKSKPYFELKAKYYVQLEQLKKTVDDL 232
+ L+A +LE L + DD+
Sbjct: 1517 EELERQNRALRA----ELEALLSSKDDV 1540
Score = 35.0 bits (79), Expect = 0.14
Identities = 70/313 (22%), Positives = 112/313 (35%), Gaps = 98/313 (31%)
Query: 10 SEEPAEILPPARDEEEEEEEGMEQ---------GLEEEEEVDPRIQ-------GELEKLN 53
+EE A +L + E E EG E+ LEEE+E ++ ELE L
Sbjct: 1475 AEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALL 1534
Query: 54 QSTDDINRRETELEDARQKFRSVLVEATVKLDELVKKIGKAVEDSKPYWEARRVARQAQL 113
S DD+ + ELE A + + ++ EL ++ A ED+K E A + Q
Sbjct: 1535 SSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDEL-TAAEDAKLRLEVTVQALKTQH 1593
Query: 114 EAQKATQDFQRATEVLRAAKE---------------TISLAEQRLLEDD----KRQFDSA 154
E +D + AK+ T+++A ++ LE + K Q SA
Sbjct: 1594 ERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASA 1653
Query: 155 ---------------------WQEMLNHATQRV---------------MEAEQTKTRSEL 178
W+E+ T R +EAE + + EL
Sbjct: 1654 GQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEEL 1713
Query: 179 VHKETAARY------------------NAAM--------GRMRQLEKKLKRAINKSKPYF 212
+ A R AA+ GR+ QLE++L+ + S+
Sbjct: 1714 AASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLN 1773
Query: 213 ELKAKYYVQLEQL 225
+ K +Q+E L
Sbjct: 1774 DRYRKLLLQVESL 1786
Score = 32.7 bits (73), Expect = 0.70
Identities = 53/264 (20%), Positives = 106/264 (40%), Gaps = 22/264 (8%)
Query: 3 AALKRSRSEEPAEILPPARDEEEEEEEGMEQGLEEEEEVDPRIQGELEKLNQSTDDINRR 62
AAL ++ + +E + + E++ + G EE E + ++ L+ N + ++R
Sbjct: 1135 AALAEAQEDLESERVARTKAEKQRRDLG-----EELEALRGELEDTLDSTNAQQELRSKR 1189
Query: 63 ETELEDARQKFRSVLVEATVKLDELVKKIGKAVEDSKPYWEARRVARQAQLEAQKATQDF 122
E E+ + ++ + EL ++ G+A+ + E AR+ + +K
Sbjct: 1190 EQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELA---EQLEQARRGKGAWEKTRLAL 1246
Query: 123 QRATEVLRAAKETISLAEQRLLEDDKRQFDSAWQEMLNHATQRVMEAEQTKTRSELVHKE 182
+ LRA ++ A Q E +R+ + QE+ R + E+ + + +
Sbjct: 1247 EAEVSELRAELSSLQTARQE-GEQRRRRLELQLQEVQG----RAGDGERARAEAAEKLQR 1301
Query: 183 TAARYNAAMGRMRQLEKKLKRAINKSKPYFELKAKYYVQLEQLKKTVDDLQAKLTLAKGE 242
A G + + E K I SK +A+ + E L+ ++ +AKL L
Sbjct: 1302 AQAELENVSGALNEAESK---TIRLSKELSSTEAQLHDAQELLQ---EETRAKLALGSRV 1355
Query: 243 YKM---ALKNLEMISDEIHERRRS 263
M A E + +E R R+
Sbjct: 1356 RAMEAEAAGLREQLEEEAAARERA 1379
Score = 29.3 bits (64), Expect = 7.7
Identities = 28/104 (26%), Positives = 50/104 (48%), Gaps = 15/104 (14%)
Query: 11 EEPAEILPPARDEEEEEE---EGMEQGLEEEEEVDPR-------IQGELEKLNQSTDDIN 60
EE + RD+ E+ + +++ LEE EE R +Q ELE + +S + +N
Sbjct: 1876 EEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMN 1935
Query: 61 RRETELEDARQK----FRSVLVEATVKLDELVKKIGKAVEDSKP 100
R T L + ++ F + V +L+E V +A E+++P
Sbjct: 1936 REVTTLRNRLRRGPLTFTTRTVRQVFRLEEGVASDEEA-EEAQP 1978
>gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens]
Length = 2036
Score = 51.6 bits (122), Expect = 1e-06
Identities = 66/281 (23%), Positives = 119/281 (42%), Gaps = 29/281 (10%)
Query: 7 RSRSEEPAEILPP---ARDEEEEEEEGMEQGLEEEEEVDPRIQGELEKLNQSTDDIN--- 60
R R EE A L AR E E + Q L E+ E R++ +L Q DD
Sbjct: 1435 RRRQEEEAGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDL 1494
Query: 61 ----RRETELEDARQKFRSVLVEATVKLDELVKKIGKAVEDSKPYWEARRVARQAQLEA- 115
+ + LE ++KF +L E + V++ +A + + EAR ++ LE
Sbjct: 1495 EQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGRER-EARALSLTRALEEE 1553
Query: 116 QKATQDFQRATEVLRAAKETISLAEQRL------LEDDKRQFDSAWQEMLNHATQ---RV 166
Q+A ++ +R LRA E + ++ + LE R + A ++ T+ +
Sbjct: 1554 QEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDEL 1613
Query: 167 MEAEQTKTRSELV--------HKETAARYNAAMGRMRQLEKKLKRAINKSKPYFELKAKY 218
AE K R E+ ++ R A R RQL K+L+ A + + +
Sbjct: 1614 TAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLA 1673
Query: 219 YVQLEQLKKTVDDLQAKLTLAKGEYKMALKNLEMISDEIHE 259
++L+ +++L+A++ A + A+K L + ++ E
Sbjct: 1674 VAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKE 1714
Score = 45.4 bits (106), Expect = 1e-04
Identities = 64/302 (21%), Positives = 126/302 (41%), Gaps = 57/302 (18%)
Query: 32 EQGLEEEEEVDPRIQGELEKLNQSTDDINRRETELEDARQKFRSVLVEATVKLDE----- 86
E+G +E E++ R+ GE +L + + +R EL + L A + ++
Sbjct: 1105 EKGRQELEKLKRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGAR 1164
Query: 87 --LVKKIGKA---VEDSKPYWEARRVARQA----------QLEAQKA----TQDFQRATE 127
L+K + +A + +++ E+ RVAR +LEA + T D A +
Sbjct: 1165 AQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQ 1224
Query: 128 VLRAAKETISLAEQRLLEDDKRQFDSAWQEMLN-----------------------HATQ 164
LR+ +E ++ LE++ R ++A QE+ T+
Sbjct: 1225 ELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTR 1284
Query: 165 RVMEAEQTKTRSELVHKETAARYNAAMGRMRQLEKKLKRAINKSKPYFELKAKYYVQLEQ 224
+EAE ++ R+EL +TA + R R+LE +L+ ++ +A+ +L++
Sbjct: 1285 LALEAEVSELRAELSSLQTARQEGEQ--RRRRLELQLQEVQGRAGDGERARAEAAEKLQR 1342
Query: 225 LKKTVDDLQAKLTLAKGEYKMALKNLEMISDEIH--------ERRRSSAMGPRGCGVGAE 276
+ ++++ L A+ + K L ++H E R A+G R + AE
Sbjct: 1343 AQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAE 1402
Query: 277 GS 278
+
Sbjct: 1403 AA 1404
Score = 45.1 bits (105), Expect = 1e-04
Identities = 55/259 (21%), Positives = 117/259 (45%), Gaps = 15/259 (5%)
Query: 8 SRSEEPAEILPPARDEEEEEEEGMEQGLEEEEEVDPRIQGELEKLNQSTDDINRRETELE 67
+ +EE L + E E +E + EEEE ++Q E ++L Q ++ E
Sbjct: 962 AEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEE 1021
Query: 68 DARQKFRSVLVEATVKLDELVKKIGKAVEDSKPYWEARRVA--RQAQLEAQKATQDFQ-R 124
ARQK + V K+ + + + + + + R++ R A+ +Q A ++ + +
Sbjct: 1022 GARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVK 1081
Query: 125 ATEVLRAAKE-TISLAEQRLLEDDKRQFDSAWQEMLNHATQRVMEAEQTKTRSELV-HKE 182
+ LR E TI+ E RL +++K + QE+ +R ++ E ++ + ++V ++
Sbjct: 1082 SLNKLRLKYEATIADMEDRLRKEEKGR-----QEL--EKLKRRLDGESSELQEQMVEQQQ 1134
Query: 183 TAARYNAAMGRMRQLEKKLKRAINKSKPYFELKAKYYVQLEQLKKTVDDLQAKLTLAKGE 242
A A +GR E++L+ A+ +++ +A+ L + + + + Q L +
Sbjct: 1135 RAEELRAQLGRK---EEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVA 1191
Query: 243 YKMALKNLEMISDEIHERR 261
A K + +E+ R
Sbjct: 1192 RTKAEKQRRDLGEELEALR 1210
Score = 42.7 bits (99), Expect = 7e-04
Identities = 48/208 (23%), Positives = 84/208 (40%), Gaps = 26/208 (12%)
Query: 25 EEEEEGMEQGLEEEEEVDPRIQGELEKLNQSTDDINRRETELEDARQKFRSVLVEATVKL 84
E E G+ + LEEE R EL+ + RR+ E A + A +
Sbjct: 1400 EAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREA 1459
Query: 85 DELVKKIGKAVEDSKPYWEARRVARQAQLEAQKATQDFQRATEVLRAAKETISLAEQRLL 144
+ L +++ + E R R+ Q E AT D ++ +++ L
Sbjct: 1460 EALTQRLAEKTETVD---RLERGRRRLQQELDDATMDLEQQRQLVST------------L 1504
Query: 145 EDDKRQFDSAWQEMLNHATQRVMEAEQTKTRSELVHKETAARYNAAMGRMRQLEKKLKRA 204
E +R+FD ++L V+ A + + R+E +E AR A+ R LE++ +
Sbjct: 1505 EKKQRKFD----QLLAEEKAAVLRAVEERERAEAEGREREAR---ALSLTRALEEEQEAR 1557
Query: 205 INKSKPYFELKAKYYVQLEQLKKTVDDL 232
+ L+A +LE L + DD+
Sbjct: 1558 EELERQNRALRA----ELEALLSSKDDV 1581
Score = 35.0 bits (79), Expect = 0.14
Identities = 70/313 (22%), Positives = 112/313 (35%), Gaps = 98/313 (31%)
Query: 10 SEEPAEILPPARDEEEEEEEGMEQ---------GLEEEEEVDPRIQ-------GELEKLN 53
+EE A +L + E E EG E+ LEEE+E ++ ELE L
Sbjct: 1516 AEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALL 1575
Query: 54 QSTDDINRRETELEDARQKFRSVLVEATVKLDELVKKIGKAVEDSKPYWEARRVARQAQL 113
S DD+ + ELE A + + ++ EL ++ A ED+K E A + Q
Sbjct: 1576 SSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDEL-TAAEDAKLRLEVTVQALKTQH 1634
Query: 114 EAQKATQDFQRATEVLRAAKE---------------TISLAEQRLLEDD----KRQFDSA 154
E +D + AK+ T+++A ++ LE + K Q SA
Sbjct: 1635 ERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASA 1694
Query: 155 ---------------------WQEMLNHATQRV---------------MEAEQTKTRSEL 178
W+E+ T R +EAE + + EL
Sbjct: 1695 GQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEEL 1754
Query: 179 VHKETAARY------------------NAAM--------GRMRQLEKKLKRAINKSKPYF 212
+ A R AA+ GR+ QLE++L+ + S+
Sbjct: 1755 AASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLN 1814
Query: 213 ELKAKYYVQLEQL 225
+ K +Q+E L
Sbjct: 1815 DRYRKLLLQVESL 1827
Score = 32.7 bits (73), Expect = 0.70
Identities = 53/264 (20%), Positives = 106/264 (40%), Gaps = 22/264 (8%)
Query: 3 AALKRSRSEEPAEILPPARDEEEEEEEGMEQGLEEEEEVDPRIQGELEKLNQSTDDINRR 62
AAL ++ + +E + + E++ + G EE E + ++ L+ N + ++R
Sbjct: 1176 AALAEAQEDLESERVARTKAEKQRRDLG-----EELEALRGELEDTLDSTNAQQELRSKR 1230
Query: 63 ETELEDARQKFRSVLVEATVKLDELVKKIGKAVEDSKPYWEARRVARQAQLEAQKATQDF 122
E E+ + ++ + EL ++ G+A+ + E AR+ + +K
Sbjct: 1231 EQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELA---EQLEQARRGKGAWEKTRLAL 1287
Query: 123 QRATEVLRAAKETISLAEQRLLEDDKRQFDSAWQEMLNHATQRVMEAEQTKTRSELVHKE 182
+ LRA ++ A Q E +R+ + QE+ R + E+ + + +
Sbjct: 1288 EAEVSELRAELSSLQTARQE-GEQRRRRLELQLQEVQG----RAGDGERARAEAAEKLQR 1342
Query: 183 TAARYNAAMGRMRQLEKKLKRAINKSKPYFELKAKYYVQLEQLKKTVDDLQAKLTLAKGE 242
A G + + E K I SK +A+ + E L+ ++ +AKL L
Sbjct: 1343 AQAELENVSGALNEAESK---TIRLSKELSSTEAQLHDAQELLQ---EETRAKLALGSRV 1396
Query: 243 YKM---ALKNLEMISDEIHERRRS 263
M A E + +E R R+
Sbjct: 1397 RAMEAEAAGLREQLEEEAAARERA 1420
Score = 29.3 bits (64), Expect = 7.7
Identities = 28/104 (26%), Positives = 50/104 (48%), Gaps = 15/104 (14%)
Query: 11 EEPAEILPPARDEEEEEE---EGMEQGLEEEEEVDPR-------IQGELEKLNQSTDDIN 60
EE + RD+ E+ + +++ LEE EE R +Q ELE + +S + +N
Sbjct: 1917 EEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMN 1976
Query: 61 RRETELEDARQK----FRSVLVEATVKLDELVKKIGKAVEDSKP 100
R T L + ++ F + V +L+E V +A E+++P
Sbjct: 1977 REVTTLRNRLRRGPLTFTTRTVRQVFRLEEGVASDEEA-EEAQP 2019
>gi|239745153 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 50.8 bits (120), Expect = 2e-06
Identities = 45/227 (19%), Positives = 103/227 (45%), Gaps = 9/227 (3%)
Query: 21 RDEEE--EEEEGMEQGLEEEEEVDPRIQGELEKLNQSTDDINRRETELEDARQKFRSVLV 78
R EE+ E+EE + + E+ + +I+ + EK+ + +++ R+E ++ + +K + +
Sbjct: 350 RQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMW 409
Query: 79 EATVKLDELVKKIGKAVEDSKPYWEARRVARQAQLEAQKATQDFQRATEVLRAAKETISL 138
K+ E +KI E + W R+ + Q + + E ++ +E +
Sbjct: 410 RQEKKMREQDEKIR---EQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQE 466
Query: 139 AEQRLLEDDKR---QFDSAW-QEMLNHATQRVMEAEQTKTRSELVHKETAARYNAAMGRM 194
E+++ +++ Q + W QE L +++ E E+ R E E + +M
Sbjct: 467 QEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKM 526
Query: 195 RQLEKKLKRAINKSKPYFELKAKYYVQLEQLKKTVDDLQAKLTLAKG 241
++ E+K++ + E + V+L++L++ + L K L G
Sbjct: 527 QRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAELLGG 573
Score = 41.2 bits (95), Expect = 0.002
Identities = 37/205 (18%), Positives = 93/205 (45%), Gaps = 4/205 (1%)
Query: 6 KRSRSEEPAEILPPARDEEEEEEEGMEQGL-EEEEEVDPRIQGELEKLNQSTDDINRRET 64
K R EE E+EEE E+ + E+EE+ ++ + +K+ + + I +E
Sbjct: 368 KMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEE 427
Query: 65 ELEDARQKFRSVLVEATVKLDELVKKIGKAVEDSKPYWEARRVARQAQLEAQKATQDFQR 124
E+ +K R L E +E ++++ + +++ + + + Q Q E + ++
Sbjct: 428 EMWRQEEKIRE-LEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTW 486
Query: 125 ATEVLRAAKETISLAEQRLLEDDKRQFDSAWQEMLNHATQRVMEAEQTKTRSELVHKETA 184
E L +E I E+++ +++ ++ +E + +++ E+ E+ +
Sbjct: 487 RQEKLLKQEEKIWEQEEKMWRQEEKMWEQ--EEKMQEQEEKMQRQEEKMREQEVRLWQQE 544
Query: 185 ARYNAAMGRMRQLEKKLKRAINKSK 209
+ R+++LE++L + K++
Sbjct: 545 EKMQEQEVRLQELEERLGKLGQKAE 569
Score = 39.7 bits (91), Expect = 0.006
Identities = 45/256 (17%), Positives = 108/256 (42%), Gaps = 22/256 (8%)
Query: 9 RSEEPAEILPPARDEEEEEEE----------GMEQGLEEEEEVDPRIQGELEKLNQSTDD 58
R E A++L P + + E + ++ +EE E + Q + EK+ + +
Sbjct: 246 RKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEK 305
Query: 59 INRRETELEDARQKFRSVLVEATVKLDELVKKIGKAVEDSKPYWEARRVARQAQLEAQKA 118
I +E ++ + K R + + +++ ++ K E W R+ + + ++
Sbjct: 306 IQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQ 365
Query: 119 TQDFQRATEVLRAAKETIS-------LAEQRLLEDDKRQFDSAW--QEMLNHATQRVMEA 169
+ R E +R E I E+++ E ++++ + W ++ + +++ E
Sbjct: 366 EEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQ 425
Query: 170 EQTKTRSELVHKETAARYNAAMGRMRQLEKKLKRAINKSKPYFELKAKYYVQLEQLKKTV 229
E+ R E +E ++R++E+K++ K + E + K Q E++++
Sbjct: 426 EEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQ---EQEEKIQRQEEKIQEQE 482
Query: 230 DDLQAKLTLAKGEYKM 245
+ + L K E K+
Sbjct: 483 EKTWRQEKLLKQEEKI 498
>gi|239745127 PREDICTED: similar to Putative golgin subfamily A
member 6-like protein 6 [Homo sapiens]
Length = 655
Score = 50.8 bits (120), Expect = 2e-06
Identities = 45/227 (19%), Positives = 103/227 (45%), Gaps = 9/227 (3%)
Query: 21 RDEEE--EEEEGMEQGLEEEEEVDPRIQGELEKLNQSTDDINRRETELEDARQKFRSVLV 78
R EE+ E+EE + + E+ + +I+ + EK+ + +++ R+E ++ + +K + +
Sbjct: 350 RQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMW 409
Query: 79 EATVKLDELVKKIGKAVEDSKPYWEARRVARQAQLEAQKATQDFQRATEVLRAAKETISL 138
K+ E +KI E + W R+ + Q + + E ++ +E +
Sbjct: 410 RQEKKMREQDEKIR---EQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQE 466
Query: 139 AEQRLLEDDKR---QFDSAW-QEMLNHATQRVMEAEQTKTRSELVHKETAARYNAAMGRM 194
E+++ +++ Q + W QE L +++ E E+ R E E + +M
Sbjct: 467 QEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKM 526
Query: 195 RQLEKKLKRAINKSKPYFELKAKYYVQLEQLKKTVDDLQAKLTLAKG 241
++ E+K++ + E + V+L++L++ + L K L G
Sbjct: 527 QRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAELLGG 573
Score = 41.2 bits (95), Expect = 0.002
Identities = 37/205 (18%), Positives = 93/205 (45%), Gaps = 4/205 (1%)
Query: 6 KRSRSEEPAEILPPARDEEEEEEEGMEQGL-EEEEEVDPRIQGELEKLNQSTDDINRRET 64
K R EE E+EEE E+ + E+EE+ ++ + +K+ + + I +E
Sbjct: 368 KMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEE 427
Query: 65 ELEDARQKFRSVLVEATVKLDELVKKIGKAVEDSKPYWEARRVARQAQLEAQKATQDFQR 124
E+ +K R L E +E ++++ + +++ + + + Q Q E + ++
Sbjct: 428 EMWRQEEKIRE-LEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTW 486
Query: 125 ATEVLRAAKETISLAEQRLLEDDKRQFDSAWQEMLNHATQRVMEAEQTKTRSELVHKETA 184
E L +E I E+++ +++ ++ +E + +++ E+ E+ +
Sbjct: 487 RQEKLLKQEEKIWEQEEKMWRQEEKMWEQ--EEKMQEQEEKMQRQEEKMREQEVRLWQQE 544
Query: 185 ARYNAAMGRMRQLEKKLKRAINKSK 209
+ R+++LE++L + K++
Sbjct: 545 EKMQEQEVRLQELEERLGKLGQKAE 569
Score = 39.7 bits (91), Expect = 0.006
Identities = 45/256 (17%), Positives = 108/256 (42%), Gaps = 22/256 (8%)
Query: 9 RSEEPAEILPPARDEEEEEEE----------GMEQGLEEEEEVDPRIQGELEKLNQSTDD 58
R E A++L P + + E + ++ +EE E + Q + EK+ + +
Sbjct: 246 RKLERAQLLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEK 305
Query: 59 INRRETELEDARQKFRSVLVEATVKLDELVKKIGKAVEDSKPYWEARRVARQAQLEAQKA 118
I +E ++ + K R + + +++ ++ K E W R+ + + ++
Sbjct: 306 IQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQEEKIREQ 365
Query: 119 TQDFQRATEVLRAAKETIS-------LAEQRLLEDDKRQFDSAW--QEMLNHATQRVMEA 169
+ R E +R E I E+++ E ++++ + W ++ + +++ E
Sbjct: 366 EEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQ 425
Query: 170 EQTKTRSELVHKETAARYNAAMGRMRQLEKKLKRAINKSKPYFELKAKYYVQLEQLKKTV 229
E+ R E +E ++R++E+K++ K + E + K Q E++++
Sbjct: 426 EEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQ---EQEEKIQRQEEKIQEQE 482
Query: 230 DDLQAKLTLAKGEYKM 245
+ + L K E K+
Sbjct: 483 EKTWRQEKLLKQEEKI 498
>gi|4505257 moesin [Homo sapiens]
Length = 577
Score = 50.8 bits (120), Expect = 2e-06
Identities = 51/191 (26%), Positives = 85/191 (44%), Gaps = 18/191 (9%)
Query: 6 KRSRSEEPAEILPPARDEEEEEEEGMEQGLEEEEEVDPRIQGELEKLNQSTDDINRRETE 65
+R R++ AE L R E EE +E + Q ++++ ++ E+ +L R ++
Sbjct: 378 ERKRAQSEAEKLAKERQEAEEAKEALLQASRDQKKTQEQLALEMAELTA-------RISQ 430
Query: 66 LEDARQKFRSVLVEATVKLDELVKKIGKAVEDSKPYWEARRVARQAQLEAQKATQDFQRA 125
LE ARQK S VE K + + + K + K VA A+ E + ++ A
Sbjct: 431 LEMARQKKESEAVEWQQKAQMVQEDLEKTRAELKTAMSTPHVAEPAENEQDEQDENGAEA 490
Query: 126 TEVLRA-AKETISLAEQRLLEDDKRQFDSAWQEMLNHATQRVMEA--EQTKTRSELVHKE 182
+ LRA A E+R E +K + Q+ L T + A E KT ++++H E
Sbjct: 491 SADLRADAMAKDRSEEERTTEAEKNE---RVQKHLKALTSELANARDESKKTANDMIHAE 547
Query: 183 TAARYNAAMGR 193
N +GR
Sbjct: 548 -----NMRLGR 553
Score = 48.9 bits (115), Expect = 9e-06
Identities = 37/162 (22%), Positives = 83/162 (51%), Gaps = 8/162 (4%)
Query: 20 ARDEEEEEEEGMEQG-LEEEEEVDPRIQGELEKLNQSTDDINRRETELEDARQKFRSVLV 78
A+ EE+ ++ ME+ LE E++ + E EK+ + +++ R ++E+ +K + L
Sbjct: 307 AQAREEKHQKQMERAMLENEKKKREMAEKEKEKIEREKEELMERLKQIEEQTKKAQQELE 366
Query: 79 EATVKLDELVKKIGKAVEDSKPYWEARRVARQAQLEAQKATQDFQRATE--VLRAAKETI 136
E T + EL ++ +A +++ + R+ A +A+ +A++D ++ E L A+ T
Sbjct: 367 EQTRRALELEQERKRAQSEAEKLAKERQEAEEAKEALLQASRDQKKTQEQLALEMAELTA 426
Query: 137 SLAEQRLLEDDKRQFDSAWQEMLNHATQRVMEAEQTKTRSEL 178
+++ + K WQ+ ++++ + KTR+EL
Sbjct: 427 RISQLEMARQKKESEAVEWQQ-----KAQMVQEDLEKTRAEL 463
Score = 42.0 bits (97), Expect = 0.001
Identities = 58/262 (22%), Positives = 102/262 (38%), Gaps = 42/262 (16%)
Query: 15 EILPPARDEEEEEEEGMEQGLEEEEEVDPRIQGELEKLNQSTDDINRRETELEDARQKFR 74
E+ +++ E E+E + + L++ EE + Q ELE + RR ELE R++ +
Sbjct: 331 EMAEKEKEKIEREKEELMERLKQIEEQTKKAQQELE-------EQTRRALELEQERKRAQ 383
Query: 75 S---VLVEATVKLDELVKKIGKAVEDSKPYWE------ARRVARQAQLE----------- 114
S L + + +E + + +A D K E A AR +QLE
Sbjct: 384 SEAEKLAKERQEAEEAKEALLQASRDQKKTQEQLALEMAELTARISQLEMARQKKESEAV 443
Query: 115 -----AQKATQDFQRATEVLRAAKETISLAEQRLLEDDKRQFDSAWQEMLNHATQRVMEA 169
AQ +D ++ L+ A T +AE E D++ + A A+ +
Sbjct: 444 EWQQKAQMVQEDLEKTRAELKTAMSTPHVAEPAENEQDEQDENGA------EASADLRAD 497
Query: 170 EQTKTRSELVHKETAARYNAAMGRMRQLEKKLKRAINKSKPYFELKAKYYVQLEQLKKTV 229
K RSE A + ++ L +L A ++SK A + E ++
Sbjct: 498 AMAKDRSEEERTTEAEKNERVQKHLKALTSELANARDESKK----TANDMIHAENMRLGR 553
Query: 230 DDLQAKLTLAKGEYKMALKNLE 251
D + + +G K + E
Sbjct: 554 DKYKTLRQIRQGNTKQRIDEFE 575
>gi|63252898 tropomyosin 1 alpha chain isoform 1 [Homo sapiens]
Length = 284
Score = 50.8 bits (120), Expect = 2e-06
Identities = 51/261 (19%), Positives = 116/261 (44%), Gaps = 33/261 (12%)
Query: 20 ARDEEEEEEEGMEQGLEEEEEVDPRIQGELEKLNQSTDDINRRETELEDARQKFRSVLVE 79
A D E+ E + + ++++ + +KL + D++++ L+DA++K +
Sbjct: 18 ALDRAEQAEADKKAAEDRSKQLEDELVSLQKKLKGTEDELDKYSEALKDAQEKLELAEKK 77
Query: 80 AT---VKLDELVKKIGKAVEDSKPYWEARRVARQAQLEAQKATQDFQRATEVL--RAAKE 134
AT + L ++I E+ E A Q EA+KA + +R +V+ RA K+
Sbjct: 78 ATDAEADVASLNRRIQLVEEELDRAQERLATALQKLEEAEKAADESERGMKVIESRAQKD 137
Query: 135 T-------ISLAEQRLLEDDKRQFDSAWQEMLNHATQRVMEAEQTKTRSELVHKETAARY 187
I L E + + +D D ++E+ + E+ + R+EL
Sbjct: 138 EEKMEIQEIQLKEAKHIAEDA---DRKYEEVARKLVIIESDLERAEERAEL--------- 185
Query: 188 NAAMGRMRQLEKKLKRAIN-------KSKPYFELKAKYYVQLEQLKKTVDDLQAKLTLAK 240
+ G+ +LE++LK N +++ Y + + +Y +++ L + + + + A+
Sbjct: 186 --SEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEEEIKVLSDKLKEAETRAEFAE 243
Query: 241 GEYKMALKNLEMISDEIHERR 261
K+++ + DE++ ++
Sbjct: 244 RSVTKLEKSIDDLEDELYAQK 264
Score = 31.2 bits (69), Expect = 2.0
Identities = 28/135 (20%), Positives = 59/135 (43%), Gaps = 7/135 (5%)
Query: 15 EILPPARDEEEEEEEGMEQGLEEEEEVDPRIQGELEKLNQSTDDINRRETELEDARQKF- 73
E L A + EE E+ ++ + ++ R Q + EK+ + + EDA +K+
Sbjct: 104 ERLATALQKLEEAEKAADESERGMKVIESRAQKDEEKMEIQEIQLKEAKHIAEDADRKYE 163
Query: 74 ----RSVLVEATVKLDELVKKI--GKAVEDSKPYWEARRVARQAQLEAQKATQDFQRATE 127
+ V++E+ ++ E ++ GK E + + + +A+K +Q R E
Sbjct: 164 EVARKLVIIESDLERAEERAELSEGKCAELEEELKTVTNNLKSLEAQAEKYSQKEDRYEE 223
Query: 128 VLRAAKETISLAEQR 142
++ + + AE R
Sbjct: 224 EIKVLSDKLKEAETR 238
>gi|156104908 myosin heavy chain 6 [Homo sapiens]
Length = 1939
Score = 50.8 bits (120), Expect = 2e-06
Identities = 63/274 (22%), Positives = 121/274 (44%), Gaps = 39/274 (14%)
Query: 3 AALKRSRSEEPAEILPPARDEEEEEEEGMEQGLEEEEE-------VDPRIQGELEKLNQS 55
A ++R +E+ E + A+ + + ++ L+ E V +++G+L ++
Sbjct: 1572 AEIERKLAEKDEE-MEQAKRNHQRVVDSLQTSLDAETRSRNEVLRVKKKMEGDLNEMEIQ 1630
Query: 56 TDDINRRETELEDARQKFRSVLVEATVKLDELVKKIGKAVEDSKPYWEARRVARQAQLEA 115
NR E + + +S+L + ++LD+ V + ++++ E R QA+LE
Sbjct: 1631 LSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAV-RANDDLKENIAIVERRNNLLQAELEE 1689
Query: 116 QKATQDFQRATEVLRAAKETISLAEQRLLEDDKR--QFDSAWQEMLNHATQRVMEAEQTK 173
+A V+ + + LAEQ L+E +R S ++N ++ ME++ T+
Sbjct: 1690 LRA---------VVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQ--KKKMESDLTQ 1738
Query: 174 TRSELVHKETAARYNAAMGRMRQLEKKLKRAINKSKPYFELKAKYY---VQLEQLKK--- 227
+SE+ A+ R E+K K+AI + E K LE++KK
Sbjct: 1739 LQSEV---------EEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNME 1789
Query: 228 -TVDDLQAKLTLAKG-EYKMALKNLEMISDEIHE 259
T+ DLQ +L A+ K K L+ + + E
Sbjct: 1790 QTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRE 1823
Score = 46.2 bits (108), Expect = 6e-05
Identities = 61/261 (23%), Positives = 100/261 (38%), Gaps = 30/261 (11%)
Query: 2 DAALKRSRSEEPAEILPPARDEEEEEEEGMEQGLEEEEEVDPRIQGELEKLNQSTDDINR 61
DA + EE + L + EE E + E+ R+Q E+E L + N
Sbjct: 1380 DAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNA 1439
Query: 62 RETELEDARQKFRSVLVEATVKLDELVKKIGKAVEDSKPYWEARRVARQAQLEAQKATQD 121
L+ ++ F +L E K +E ++ +++ AR E K
Sbjct: 1440 AAAALDKKQRNFDKILAEWKQKYEESQSELE----------SSQKEARSLSTELFKLKNA 1489
Query: 122 FQRATEVLRAAKETISLAEQRLLEDDKRQFDSAWQEMLNHATQRVMEAEQTKTRSELVHK 181
++ + E L ET + L E+ S E L + V E E+ + + E+
Sbjct: 1490 YEESLEHL----ETFKRENKNLQEE-----ISDLTEQLGEGGKNVHELEKVRKQLEVEKL 1540
Query: 182 ETAARYNAAMGRMRQLEKKLKRA---INKSKPYFELK-AKYYVQLEQLK----KTVDDLQ 233
E + A + E K+ RA N+ K E K A+ ++EQ K + VD LQ
Sbjct: 1541 ELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHQRVVDSLQ 1600
Query: 234 AKL---TLAKGEYKMALKNLE 251
L T ++ E K +E
Sbjct: 1601 TSLDAETRSRNEVLRVKKKME 1621
Score = 45.1 bits (105), Expect = 1e-04
Identities = 63/281 (22%), Positives = 118/281 (41%), Gaps = 41/281 (14%)
Query: 23 EEEEEEEGMEQGLEEEEEVDPRIQGELEK--------LNQSTDDINRRETELEDARQKFR 74
+ E E + M + LEE L K L + D++ R + +LE + +F+
Sbjct: 1168 KREAEFQKMRRDLEEATLQHEATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFK 1227
Query: 75 SVLVEATVKLDELVKKIGKAVEDSKPYWEARRVARQAQLEAQKATQDF--QRAT------ 126
L + T +++++K + S+ + R EAQ++ DF QRA
Sbjct: 1228 LELDDVTSNMEQIIKAKANLEKVSRTLEDQANEYRVKLEEAQRSLNDFTTQRAKLQTENG 1287
Query: 127 EVLRAAKETISLAEQ---------RLLEDDKRQFDSAW--QEMLNHATQ---------RV 166
E+ R +E +L Q + +ED KRQ + + L HA Q R
Sbjct: 1288 ELARQLEEKEALISQLTRGKLSYTQQMEDLKRQLEEEGKAKNALAHALQSARHDCDLLRE 1347
Query: 167 MEAEQTKTRSELVHKETAARYNAAMGRMRQLEKKLKRAINKSKPYFELKAKYYVQLEQLK 226
E+T+ ++EL + A A R K AI +++ E K K +L+ +
Sbjct: 1348 QYEEETEAKAELQRVLSKANSEVAQWR----TKYETDAIQRTEELEEAKKKLAQRLQDAE 1403
Query: 227 KTVDDLQAKL-TLAKGEYKMALKNLEMISDEIHERRRSSAM 266
+ V+ + AK +L K ++++ + +++ D ++A+
Sbjct: 1404 EAVEAVNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAAL 1444
Score = 41.2 bits (95), Expect = 0.002
Identities = 52/252 (20%), Positives = 106/252 (42%), Gaps = 19/252 (7%)
Query: 23 EEEEEEEGMEQGLEEEEEVDPRIQGELEKLNQSTDDINRRETELEDARQKFRSVLVEATV 82
E +++ E + LE ++ + EL KL + ++ + + + + + T
Sbjct: 1457 EWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTE 1516
Query: 83 KLDELVKKIGKAVEDSKPYWEARRVARQAQLEAQKATQDFQRATEVLRAAKETISLA--- 139
+L E K + + +E + E ++ Q+ LE +A+ + + ++LRA E +
Sbjct: 1517 QLGEGGKNVHE-LEKVRKQLEVEKLELQSALEEAEASLEHEEG-KILRAQLEFNQIKAEI 1574
Query: 140 EQRLLEDDKRQFDSAWQEMLNHATQRVMEAEQTKTRSELVHKETAARYNAAM-GRMRQLE 198
E++L E D+ Q NH QRV+++ QT +E + R M G + ++E
Sbjct: 1575 ERKLAEKDEEME----QAKRNH--QRVVDSLQTSLDAETRSRNEVLRVKKKMEGDLNEME 1628
Query: 199 KKLKRAINKS-------KPYFELKAKYYVQLEQLKKTVDDLQAKLTLAKGEYKMALKNLE 251
+L A + K L +QL+ + DDL+ + + + + LE
Sbjct: 1629 IQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELE 1688
Query: 252 MISDEIHERRRS 263
+ + + RS
Sbjct: 1689 ELRAVVEQTERS 1700
Score = 37.7 bits (86), Expect = 0.022
Identities = 57/269 (21%), Positives = 115/269 (42%), Gaps = 38/269 (14%)
Query: 10 SEEPAEILPPARDEEEEEEEGMEQGLEEEEEVDP-------RIQGELEKLNQSTDDINRR 62
+EE + L + + E + + M + LE+EEE++ +++ E +L + DD+
Sbjct: 903 AEERCDQLIKNKIQLEAKVKEMNERLEDEEEMNAELTAKKRKLEDECSELKKDIDDLELT 962
Query: 63 ETELEDARQKFRSVLVEATVKLDELVKKIGKAVEDSKPYWEARRVARQAQLEAQKATQDF 122
++E + + + T ++ L + I K ++ K EA Q+A D
Sbjct: 963 LAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAH----------QQALDDL 1012
Query: 123 QRATEVLRAAKETISLAEQRLLEDDKRQFDSAWQEMLNHATQRVMEAEQTKTRSELVHKE 182
Q + + + ++ EQ++ DD + L + M+ E+ K + E K
Sbjct: 1013 QVEEDKVNSLSKSKVKLEQQV--DD-------LEGSLEQEKKVRMDLERAKRKLEGDLKL 1063
Query: 183 TAARYNAAMGRMRQLEKKLKRA---INKSKPYFELKAKYYVQLE--------QLKKTVDD 231
T QLE+KLK+ IN+ E + +QL+ ++++ ++
Sbjct: 1064 TQESIMDLENDKLQLEEKLKKKEFDINQQNSKIEDEQVLALQLQKKLKENQARIEELEEE 1123
Query: 232 LQAKLTLAKGEYKMALKNLEMISDEIHER 260
L+A+ T A+ + + +L +EI ER
Sbjct: 1124 LEAERT-ARAKVEKLRSDLSRELEEISER 1151
>gi|4504063 golgin 97 [Homo sapiens]
Length = 767
Score = 50.8 bits (120), Expect = 2e-06
Identities = 50/206 (24%), Positives = 89/206 (43%), Gaps = 11/206 (5%)
Query: 23 EEEEEEEGMEQGLEEEEEVDPRIQGELEKLNQSTDDINRRETELEDARQKFRSVLVEATV 82
++EE MEQ LE R Q EL NQ + D++++ EL Q+ S L E
Sbjct: 190 KKEESLGKMEQELEARTRELSRTQEELMNSNQMSSDLSQKLEEL----QRHYSTLEEQRD 245
Query: 83 KLDELVKKIG---KAVEDSKPYWEARRVARQAQLEAQKATQDFQRATEVLRAAKETISLA 139
+ + K G K + E + + +Q ++ QK T + Q +V+ +E ++
Sbjct: 246 HV--IASKTGAESKITALEQKEQELQALIQQLSIDLQKVTAETQEKEDVITHLQEKVASL 303
Query: 140 EQRLLEDDKRQFDSAWQEMLNHATQRVMEAEQTKTRSELVHKETAARYNAAMGRMRQLEK 199
E+RL + + QE+L T E T+ + A N R+R+LE+
Sbjct: 304 EKRL--EQNLSGEEHVQELLKEKTLAEQNLEDTRQQLLAARSSQAKAINTLETRVRELEQ 361
Query: 200 KLKRAINKSKPYFELKAKYYVQLEQL 225
L+ + + + + A Q+++L
Sbjct: 362 TLQASEEQLQQSKGIVAAQETQIQEL 387
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.307 0.124 0.332
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,013,899
Number of Sequences: 37866
Number of extensions: 824369
Number of successful extensions: 13974
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 242
Number of HSP's successfully gapped in prelim test: 830
Number of HSP's that attempted gapping in prelim test: 8329
Number of HSP's gapped (non-prelim): 4027
length of query: 455
length of database: 18,247,518
effective HSP length: 106
effective length of query: 349
effective length of database: 14,233,722
effective search space: 4967568978
effective search space used: 4967568978
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.6 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.