Search of human proteins with 108773810

Search of human proteins with 108773810

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|108773810 leucyl-tRNA synthetase [Homo sapiens]
         (1176 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|108773810 leucyl-tRNA synthetase [Homo sapiens]                   2402   0.0  
gi|46852147 mitochondrial isoleucine tRNA synthetase [Homo sapiens]    49   2e-05
gi|7661872 leucyl-tRNA synthetase 2, mitochondrial precursor [Ho...    49   3e-05
gi|5454158 valyl-tRNA synthetase [Homo sapiens]                        44   0.001
gi|24308436 methionine-tRNA synthetase 2 precursor [Homo sapiens]      43   0.002
gi|94721239 isoleucine tRNA synthetase [Homo sapiens]                  40   0.013
gi|94721241 isoleucine tRNA synthetase [Homo sapiens]                  40   0.013
gi|21269877 cysteinyl-tRNA synthetase isoform a [Homo sapiens]         39   0.029
gi|62240994 cysteinyl-tRNA synthetase isoform d [Homo sapiens]         39   0.029
gi|62240992 cysteinyl-tRNA synthetase isoform c [Homo sapiens]         39   0.029
gi|10835051 cysteinyl-tRNA synthetase isoform b [Homo sapiens]         39   0.029
gi|55741845 valyl-tRNA synthetase 2, mitochondrial [Homo sapiens]      33   1.6  
gi|13375695 cysteinyl-tRNA synthetase 2, mitochondrial [Homo sap...    32   2.7  
gi|51599156 chromodomain helicase DNA binding protein 4 [Homo sa...    32   3.6  
gi|190194423 SPARC-like 1 [Homo sapiens]                               32   3.6  
gi|190341024 SPARC-like 1 [Homo sapiens]                               32   3.6  
gi|48255891 protein kinase C substrate 80K-H isoform 2 [Homo sap...    32   4.7  
gi|134142826 pericentriolar material 1 [Homo sapiens]                  32   4.7  
gi|157266334 tubby like protein 1 [Homo sapiens]                       32   4.7  
gi|55770834 centromere protein F [Homo sapiens]                        31   6.1  
gi|187936946 hypothetical protein LOC84140 [Homo sapiens]              31   7.9  

>gi|108773810 leucyl-tRNA synthetase [Homo sapiens]
          Length = 1176

 Score = 2402 bits (6224), Expect = 0.0
 Identities = 1176/1176 (100%), Positives = 1176/1176 (100%)

Query: 1    MAERKGTAKVDFLKKIEKEIQQKWDTERVFEVNASNLEKQTSKGKYFVTFPYPYMNGRLH 60
            MAERKGTAKVDFLKKIEKEIQQKWDTERVFEVNASNLEKQTSKGKYFVTFPYPYMNGRLH
Sbjct: 1    MAERKGTAKVDFLKKIEKEIQQKWDTERVFEVNASNLEKQTSKGKYFVTFPYPYMNGRLH 60

Query: 61   LGHTFSLSKCEFAVGYQRLKGKCCLFPFGLHCTGMPIKACADKLKREIELYGCPPDFPDE 120
            LGHTFSLSKCEFAVGYQRLKGKCCLFPFGLHCTGMPIKACADKLKREIELYGCPPDFPDE
Sbjct: 61   LGHTFSLSKCEFAVGYQRLKGKCCLFPFGLHCTGMPIKACADKLKREIELYGCPPDFPDE 120

Query: 121  EEEEEETSVKTEDIIIKDKAKGKKSKAAAKAGSSKYQWGIMKSLGLSDEEIVKFSEAEHW 180
            EEEEEETSVKTEDIIIKDKAKGKKSKAAAKAGSSKYQWGIMKSLGLSDEEIVKFSEAEHW
Sbjct: 121  EEEEEETSVKTEDIIIKDKAKGKKSKAAAKAGSSKYQWGIMKSLGLSDEEIVKFSEAEHW 180

Query: 181  LDYFPPLAIQDLKRMGLKVDWRRSFITTDVNPYYDSFVRWQFLTLRERNKIKFGKRYTIY 240
            LDYFPPLAIQDLKRMGLKVDWRRSFITTDVNPYYDSFVRWQFLTLRERNKIKFGKRYTIY
Sbjct: 181  LDYFPPLAIQDLKRMGLKVDWRRSFITTDVNPYYDSFVRWQFLTLRERNKIKFGKRYTIY 240

Query: 241  SPKDGQPCMDHDRQTGEGVGPQEYTLLKLKVLEPYPSKLSGLKGKNIFLVAATLRPETMF 300
            SPKDGQPCMDHDRQTGEGVGPQEYTLLKLKVLEPYPSKLSGLKGKNIFLVAATLRPETMF
Sbjct: 241  SPKDGQPCMDHDRQTGEGVGPQEYTLLKLKVLEPYPSKLSGLKGKNIFLVAATLRPETMF 300

Query: 301  GQTNCWVRPDMKYIGFETVNGDIFICTQKAARNMSYQGFTKDNGVVPVVKELMGEEILGA 360
            GQTNCWVRPDMKYIGFETVNGDIFICTQKAARNMSYQGFTKDNGVVPVVKELMGEEILGA
Sbjct: 301  GQTNCWVRPDMKYIGFETVNGDIFICTQKAARNMSYQGFTKDNGVVPVVKELMGEEILGA 360

Query: 361  SLSAPLTSYKVIYVLPMLTIKEDKGTGVVTSVPSDSPDDIAALRDLKKKQALRAKYGIRD 420
            SLSAPLTSYKVIYVLPMLTIKEDKGTGVVTSVPSDSPDDIAALRDLKKKQALRAKYGIRD
Sbjct: 361  SLSAPLTSYKVIYVLPMLTIKEDKGTGVVTSVPSDSPDDIAALRDLKKKQALRAKYGIRD 420

Query: 421  DMVLPFEPVPVIEIPGFGNLSAVTICDELKIQSQNDREKLAEAKEKIYLKGFYEGIMLVD 480
            DMVLPFEPVPVIEIPGFGNLSAVTICDELKIQSQNDREKLAEAKEKIYLKGFYEGIMLVD
Sbjct: 421  DMVLPFEPVPVIEIPGFGNLSAVTICDELKIQSQNDREKLAEAKEKIYLKGFYEGIMLVD 480

Query: 481  GFKGQKVQDVKKTIQKKMIDAGDALIYMEPEKQVMSRSSDECVVALCDQWYLDYGEENWK 540
            GFKGQKVQDVKKTIQKKMIDAGDALIYMEPEKQVMSRSSDECVVALCDQWYLDYGEENWK
Sbjct: 481  GFKGQKVQDVKKTIQKKMIDAGDALIYMEPEKQVMSRSSDECVVALCDQWYLDYGEENWK 540

Query: 541  KQTSQCLKNLETFCEETRRNFEATLGWLQEHACSRTYGLGTHLPWDEQWLIESLSDSTIY 600
            KQTSQCLKNLETFCEETRRNFEATLGWLQEHACSRTYGLGTHLPWDEQWLIESLSDSTIY
Sbjct: 541  KQTSQCLKNLETFCEETRRNFEATLGWLQEHACSRTYGLGTHLPWDEQWLIESLSDSTIY 600

Query: 601  MAFYTVAHLLQGGNLHGQAESPLGIRPQQMTKEVWDYVFFKEAPFPKTQIAKEKLDQLKQ 660
            MAFYTVAHLLQGGNLHGQAESPLGIRPQQMTKEVWDYVFFKEAPFPKTQIAKEKLDQLKQ
Sbjct: 601  MAFYTVAHLLQGGNLHGQAESPLGIRPQQMTKEVWDYVFFKEAPFPKTQIAKEKLDQLKQ 660

Query: 661  EFEFWYPVDLRVSGKDLVPNHLSYYLYNHVAMWPEQSDKWPTAVRANGHLLLNSEKMSKS 720
            EFEFWYPVDLRVSGKDLVPNHLSYYLYNHVAMWPEQSDKWPTAVRANGHLLLNSEKMSKS
Sbjct: 661  EFEFWYPVDLRVSGKDLVPNHLSYYLYNHVAMWPEQSDKWPTAVRANGHLLLNSEKMSKS 720

Query: 721  TGNFLTLTQAIDKFSADGMRLALADAGDTVEDANFVEAMADAGILRLYTWVEWVKEMVAN 780
            TGNFLTLTQAIDKFSADGMRLALADAGDTVEDANFVEAMADAGILRLYTWVEWVKEMVAN
Sbjct: 721  TGNFLTLTQAIDKFSADGMRLALADAGDTVEDANFVEAMADAGILRLYTWVEWVKEMVAN 780

Query: 781  WDSLRSGPASTFNDRVFASELNAGIIKTDQNYEKMMFKEALKTGFFEFQAAKDKYRELAV 840
            WDSLRSGPASTFNDRVFASELNAGIIKTDQNYEKMMFKEALKTGFFEFQAAKDKYRELAV
Sbjct: 781  WDSLRSGPASTFNDRVFASELNAGIIKTDQNYEKMMFKEALKTGFFEFQAAKDKYRELAV 840

Query: 841  EGMHRELVFRFIEVQTLLLAPFCPHLCEHIWTLLGKPDSIMNASWPVAGPVNEVLIHSSQ 900
            EGMHRELVFRFIEVQTLLLAPFCPHLCEHIWTLLGKPDSIMNASWPVAGPVNEVLIHSSQ
Sbjct: 841  EGMHRELVFRFIEVQTLLLAPFCPHLCEHIWTLLGKPDSIMNASWPVAGPVNEVLIHSSQ 900

Query: 901  YLMEVTHDLRLRLKNYMMPAKGKKTDKQPLQKPSHCTIYVAKNYPPWQHTTLSVLRKHFE 960
            YLMEVTHDLRLRLKNYMMPAKGKKTDKQPLQKPSHCTIYVAKNYPPWQHTTLSVLRKHFE
Sbjct: 901  YLMEVTHDLRLRLKNYMMPAKGKKTDKQPLQKPSHCTIYVAKNYPPWQHTTLSVLRKHFE 960

Query: 961  ANNGKLPDNKVIASELGSMPELKKYMKKVMPFVAMIKENLEKMGPRILDLQLEFDEKAVL 1020
            ANNGKLPDNKVIASELGSMPELKKYMKKVMPFVAMIKENLEKMGPRILDLQLEFDEKAVL
Sbjct: 961  ANNGKLPDNKVIASELGSMPELKKYMKKVMPFVAMIKENLEKMGPRILDLQLEFDEKAVL 1020

Query: 1021 MENIVYLTNSLELEHIEVKFASEAEDKIREDCCPGKPLNVFRIEPGVSVSLVNPQPSNGH 1080
            MENIVYLTNSLELEHIEVKFASEAEDKIREDCCPGKPLNVFRIEPGVSVSLVNPQPSNGH
Sbjct: 1021 MENIVYLTNSLELEHIEVKFASEAEDKIREDCCPGKPLNVFRIEPGVSVSLVNPQPSNGH 1080

Query: 1081 FSTKIEIRQGDNCDSIIRRLMKMNRGIKDLSKVKLMRFDDPLLGPRRVPVLGKEYTEKTP 1140
            FSTKIEIRQGDNCDSIIRRLMKMNRGIKDLSKVKLMRFDDPLLGPRRVPVLGKEYTEKTP
Sbjct: 1081 FSTKIEIRQGDNCDSIIRRLMKMNRGIKDLSKVKLMRFDDPLLGPRRVPVLGKEYTEKTP 1140

Query: 1141 ISEHAVFNVDLMSKKIHLTENGIRVDIGDTIIYLVH 1176
            ISEHAVFNVDLMSKKIHLTENGIRVDIGDTIIYLVH
Sbjct: 1141 ISEHAVFNVDLMSKKIHLTENGIRVDIGDTIIYLVH 1176


>gi|46852147 mitochondrial isoleucine tRNA synthetase [Homo sapiens]
          Length = 1012

 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 79/387 (20%), Positives = 142/387 (36%), Gaps = 73/387 (18%)

Query: 17  EKEIQQKWDTERVFEVNASNLEKQTSKGKYFVTFPYPYMNGRLHLGHTFSLSKCEFAVGY 76
           E EIQQK     ++    S   ++  K ++ +    PY NG  H+GH  +    + A  +
Sbjct: 84  ELEIQQKCGFSELY----SWQRERKVKTEFCLHDGPPYANGDPHVGHALNKILKDIANRF 139

Query: 77  QRLKGKCCLFPFGLHCTGMPIKA-CADKLKREIELYGCPPDFPDEEEEEEETSVKTEDII 135
             + G    F  G  C G+PI+     +L RE +                        + 
Sbjct: 140 HMMNGSKIHFVPGWDCHGLPIEIKVLSELGREAQ--------------------NLSAME 179

Query: 136 IKDKAKGKKSKAAAKAGSSKYQWGIMKSLGLSDEEIVKFSEAEHWLDYFPPLAIQDLKRM 195
           I+ KA+     A  K  S+  +WGIM                                  
Sbjct: 180 IRKKARSFAKAAIEKQKSAFIRWGIM---------------------------------- 205

Query: 196 GLKVDWRRSFITTDVNPYYDSFVRWQFLTLRERNKIKFGKRYTIYSPKDGQPCMDHDRQT 255
               DW   + T D    Y++     F  + ++  +    +   +SP       + + + 
Sbjct: 206 ---ADWNNCYYTFDGK--YEAKQLRTFYQMYDKGLVYRSYKPVFWSPSSRTALAEAELEY 260

Query: 256 G-EGVGPQEYTLLKLKVLEPYPSKLSGLKGKN-IFLVAATLRPETMFGQTNCWVRPDMKY 313
             E V    Y  +K  +L+P P   S + G + + ++  T +P T+         P+ KY
Sbjct: 261 NPEHVSRSIY--VKFPLLKPSPKLASLIDGSSPVSILVWTTQPWTIPANEAVCYMPESKY 318

Query: 314 IGFE-TVNGDIFICTQKAARNMSYQGFTKDNGVVPVVKELMGEEILGASLSAPLTSYKVI 372
              + + +GD+++    AA  ++    T +      +  L G ++   + S PL   K  
Sbjct: 319 AVVKCSKSGDLYVL---AADKVASVASTLET-TFETISTLSGVDLENGTCSHPLIPDKAS 374

Query: 373 YVLPMLTIKEDKGTGVVTSVPSDSPDD 399
            +LP   +   KGTG+V + P+   +D
Sbjct: 375 PLLPANHVTMAKGTGLVHTAPAHGMED 401


>gi|7661872 leucyl-tRNA synthetase 2, mitochondrial precursor [Homo
           sapiens]
          Length = 903

 Score = 48.9 bits (115), Expect = 3e-05
 Identities = 23/80 (28%), Positives = 42/80 (52%)

Query: 22  QKWDTERVFEVNASNLEKQTSKGKYFVTFPYPYMNGRLHLGHTFSLSKCEFAVGYQRLKG 81
           +KW  +R+ E  +   E   SK K++V   +PY +G+LH+GH    +  +    +Q+++G
Sbjct: 60  EKWWHQRIKEQASKISEADKSKPKFYVLSMFPYPSGKLHMGHVRVYTISDTIARFQKMRG 119

Query: 82  KCCLFPFGLHCTGMPIKACA 101
              + P G    G+P +  A
Sbjct: 120 MQVINPMGWDAFGLPAENAA 139


>gi|5454158 valyl-tRNA synthetase [Homo sapiens]
          Length = 1264

 Score = 43.5 bits (101), Expect = 0.001
 Identities = 143/745 (19%), Positives = 242/745 (32%), Gaps = 187/745 (25%)

Query: 24  WDTERVF--EVNASNLEKQTSKGKYFVTFPYPYMNGRLHLGHTFSLSKCEFAVGYQRLKG 81
           W+ +  F  E    N+     +G + +  P P + G LHLGH  + +  +    + R++G
Sbjct: 313 WEQQGFFKPEYGRPNVSAANPRGVFMMCIPPPNVTGSLHLGHALTNAIQDSLTRWHRMRG 372

Query: 82  KCCLFPFGLHCTGMPIKACADKLKREIELYGCPPDFPDEEEEEEETSVKTEDIIIKDKAK 141
           +  L+  G    G+  +   +K                                      
Sbjct: 373 ETTLWNPGCDHAGIATQVVVEK-------------------------------------- 394

Query: 142 GKKSKAAAKAGSSKYQWGIMKSLGLSDEEIVKFSEAEHWLDYFPPLAIQDLKRMGLKVDW 201
               K   + G S++Q G    L    +E+ K+ E +    Y        LK++G  +DW
Sbjct: 395 ----KLWREQGLSRHQLGREAFL----QEVWKWKEEKGDRIY------HQLKKLGSSLDW 440

Query: 202 RRSFITTDVNPYYDSFVRWQFLTLRERNKIKFGKRYTIYSPKDGQPCMDHDRQTGEGVG- 260
            R+  T D  P   + V   F+ L E   I    R   +S        D +    E  G 
Sbjct: 441 DRACFTMD--PKLSAAVTEAFVRLHEEGIIYRSTRLVNWSCTLNSAISDIEVDKKELTGR 498

Query: 261 -----PQEYTLLKLKVLEPYPSKLSGLKGKNIFLVAATLRPETMFGQTNCWVRPDMKYIG 315
                P     ++  VL  +  K+ G    +  +V AT R ETM G     V P      
Sbjct: 499 TLLSVPGYKEKVEFGVLVSFAYKVQG-SDSDEEVVVATTRIETMLGDVAVAVHP------ 551

Query: 316 FETVNGDIFICTQKAARNMSYQGFTKDNGVVPVVKELMGEEILGASLSAPLTSYKVIYVL 375
                           ++  YQ     N + P +           S S P+   + + + 
Sbjct: 552 ----------------KDTRYQHLKGKNVIHPFL-----------SRSLPIVFDEFVDM- 583

Query: 376 PMLTIKEDKGTGVVTSVPSDSPDDIAALRDLKKKQALRAKYGIRDDMVLPFEPVPVIEIP 435
                  D GTG V   P+   +D     ++ ++  L A   +     L   P P + +P
Sbjct: 584 -------DFGTGAVKITPAHDQNDY----EVGQRHGLEAISIMDSRGALINVPPPFLGLP 632

Query: 436 GFGNLSAVTICDELKIQSQNDREKLAEAKEKIYLKGFYEGIMLVDGFKGQKVQDVKKTIQ 495
            F    AV                L   KE+   +G  +  M+V                
Sbjct: 633 RFEARKAV----------------LVALKERGLFRGIEDNPMVV---------------- 660

Query: 496 KKMIDAGDALIYMEPEKQVMSRSSDECVVALCDQWYLDYGEENWKKQTSQCLKNLETFCE 555
                             + +RS D     L  QWY+  GE       +    +L    E
Sbjct: 661 -----------------PLCNRSKDVVEPLLRPQWYVRCGEMAQAASAAVTRGDLRILPE 703

Query: 556 ETRRNFEATLGWLQEHACSRTYGLGTHLPWDEQWLIESLSDSTIYMAFYTVAHLLQGGNL 615
             +R + A +  ++E   SR    G  +P        ++SD  +             G  
Sbjct: 704 AHQRTWHAWMDNIREWCISRQLWWGHRIP----AYFVTVSDPAVPPGEDPDGRYWVSGRN 759

Query: 616 HGQAE----SPLGIRPQ----QMTKEVWDYVFFKEAPFPKTQIAKEKLDQLKQEFEFWYP 667
             +A        G+ P     Q  ++V D  +F    FP + +         ++   +YP
Sbjct: 760 EAEAREKAAKEFGVSPDKISLQQDEDVLD-TWFSSGLFPLSILG---WPNQSEDLSVFYP 815

Query: 668 VDLRVSGKDLVPNHLSYYLYNHVAMWPEQSDKWP------TAVRANGHLLLNSEKMSKST 721
             L  +G D+    L +++   V +  + + + P       A+  + H      KMSKS 
Sbjct: 816 GTLLETGHDI----LFFWVARMVMLGLKLTGRLPFREVYLHAIVRDAH----GRKMSKSL 867

Query: 722 GNFLTLTQAIDKFSADGMRLALADA 746
           GN +     I   S  G+   L ++
Sbjct: 868 GNVIDPLDVIYGISLQGLHNQLLNS 892


>gi|24308436 methionine-tRNA synthetase 2 precursor [Homo sapiens]
          Length = 593

 Score = 43.1 bits (100), Expect = 0.002
 Identities = 26/99 (26%), Positives = 45/99 (45%), Gaps = 8/99 (8%)

Query: 661 EFEFWYPVDLRVSGKDLVPNHLSYY--LYNHVAMWPEQSDKWPTAVRANGHLLLNSEKMS 718
           EF+ W+P    + GKD++  H  Y+        M P      P  +  + H  +  +KMS
Sbjct: 296 EFKSWWPATSHIIGKDILKFHAIYWPAFLLGAGMSP------PQRICVHSHWTVCGQKMS 349

Query: 719 KSTGNFLTLTQAIDKFSADGMRLALADAGDTVEDANFVE 757
           KS GN +     +++++ DG R  L   G    D ++ +
Sbjct: 350 KSLGNVVDPRTCLNRYTVDGFRYFLLRQGVPNWDCDYYD 388



 Score = 31.2 bits (69), Expect = 6.1
 Identities = 31/129 (24%), Positives = 52/129 (40%), Gaps = 23/129 (17%)

Query: 46  YFVTFPYPYMNGRLHLGHTFSLSKCEFAVGYQRLKG---KCCLFPFGLHCTGMPIKACAD 102
           YF T P  Y+N   H+GH +S    +    ++RL+G       F  G    G+ I+  A 
Sbjct: 46  YFTT-PIFYVNAAPHIGHLYSALLADALCRHRRLRGPSTAATRFSTGTDEHGLKIQQAAA 104

Query: 103 KLKREIELYGCPPDFPDEEEEE-----EETSVKTEDIIIKDKAKGKKSKAAAKAGSSKYQ 157
                      P +  D   E+     +E  +   D I   +A+ +         + ++ 
Sbjct: 105 TAGL------APTELCDRVSEQFQQLFQEAGISCTDFIRTTEARHRV--------AVQHF 150

Query: 158 WGIMKSLGL 166
           WG++KS GL
Sbjct: 151 WGVLKSRGL 159


>gi|94721239 isoleucine tRNA synthetase [Homo sapiens]
          Length = 1262

 Score = 40.0 bits (92), Expect = 0.013
 Identities = 120/582 (20%), Positives = 206/582 (35%), Gaps = 113/582 (19%)

Query: 192 LKRMGLKVDWRRSFITTDVNPYYDSFVRWQFLTLRERNKIKFGKRYTIYSPKDGQPCMDH 251
           + R+G  +D+   + T  + P +   V W F  L ++  +  G +   +S     P  + 
Sbjct: 135 VSRLGRWIDFDNDYKT--LYPQFMESVWWVFKQLYDKGLVYRGVKVMPFSTACNTPLSNF 192

Query: 252 DRQTGEGVGPQEYTLLK-LKVLEPYPSKLSGLKGKNIFLVAATLRPETMFGQTNCWVRPD 310
           +         Q Y  ++   V   +P +    + + + LVA T  P T+       V P+
Sbjct: 193 ESH-------QNYKDVQDPSVFVTFPLE----EDETVSLVAWTTTPWTLPSNLAVCVNPE 241

Query: 311 MKYIGFETVNGDIFICTQKAARNMSYQGFTKDNGVVPVVKELMGEEILGASLSAPLTSYK 370
           M+Y+  + V     +   +A  +  Y    K      +++   G  + G     PL  Y 
Sbjct: 242 MQYVKIKDVARGRLLILMEARLSALY----KLESDYEILERFPGAYLKGKKYR-PLFDYF 296

Query: 371 V-------IYVLPMLTIKEDKGTGVVTSVPSDSPDDIAALRDLKKKQALRAKYGIRDDMV 423
           +         VL    +KE++GTGVV   P    +D     D                 +
Sbjct: 297 LKCKENGAFTVLVDNYVKEEEGTGVVHQAPYFGAEDYRVCMDFN---------------I 341

Query: 424 LPFEPVPVIEIPGFGNLSAVTICDELKIQSQNDREKLAEAKEKIYLKGFYEGIMLVDGFK 483
           +  + +PV  +   G  +                                     V  F 
Sbjct: 342 IRKDSLPVCPVDASGCFTTE-----------------------------------VTDFA 366

Query: 484 GQKVQDVKKTIQKKMIDAGDALIY--MEPEKQVMSRSSDECVVALCDQWYLDYGEENWKK 541
           GQ V+D  K+I + + + G  L+            RS    +      W++       + 
Sbjct: 367 GQYVKDADKSIIRTLKEQGRLLVATTFTHSYPFCWRSDTPLIYKAVPSWFVRV-----EN 421

Query: 542 QTSQCLKNLETFCEETRRNFEATLG-WLQEH---ACSRTYGLGTHLPWDEQWLIESLSDS 597
              Q L+N +          E   G WL++      SR    GT +P    W+ +   + 
Sbjct: 422 MVDQLLRNNDLCYWVPELVREKRFGNWLKDARDWTISRNRYWGTPIPL---WVSDDFEE- 477

Query: 598 TIYMAFYTVAHL--LQGG---NLHGQAESPLGIRPQQMTK-------EVWDYVFFKEAPF 645
              +   +VA L  L G    +LH ++   L I P +  K       EV+D  +F+    
Sbjct: 478 --VVCIGSVAELEELSGAKISDLHRESVDHLTI-PSRCGKGSLHRISEVFD-CWFESGSM 533

Query: 646 PKTQIAKEKLDQLKQEFEFWYPVDLRVSGKDLVPNHLSYYLYNHVAMWPEQSDKWPTAVR 705
           P  Q+      + K+EFE  +P D    G D         L    A++ +   K    V 
Sbjct: 534 PYAQVHYPF--ENKREFEDAFPADFIAEGIDQTRGWFYTLLVLATALFGQPPFK---NVI 588

Query: 706 ANGHLLLNS-EKMSKSTGNFLTLTQAIDKFSADGMRLALADA 746
            NG +L +  +KMSK   N+      I K+ AD +RL L ++
Sbjct: 589 VNGLVLASDGQKMSKRKKNYPDPVSIIQKYGADALRLYLINS 630


>gi|94721241 isoleucine tRNA synthetase [Homo sapiens]
          Length = 1262

 Score = 40.0 bits (92), Expect = 0.013
 Identities = 120/582 (20%), Positives = 206/582 (35%), Gaps = 113/582 (19%)

Query: 192 LKRMGLKVDWRRSFITTDVNPYYDSFVRWQFLTLRERNKIKFGKRYTIYSPKDGQPCMDH 251
           + R+G  +D+   + T  + P +   V W F  L ++  +  G +   +S     P  + 
Sbjct: 135 VSRLGRWIDFDNDYKT--LYPQFMESVWWVFKQLYDKGLVYRGVKVMPFSTACNTPLSNF 192

Query: 252 DRQTGEGVGPQEYTLLK-LKVLEPYPSKLSGLKGKNIFLVAATLRPETMFGQTNCWVRPD 310
           +         Q Y  ++   V   +P +    + + + LVA T  P T+       V P+
Sbjct: 193 ESH-------QNYKDVQDPSVFVTFPLE----EDETVSLVAWTTTPWTLPSNLAVCVNPE 241

Query: 311 MKYIGFETVNGDIFICTQKAARNMSYQGFTKDNGVVPVVKELMGEEILGASLSAPLTSYK 370
           M+Y+  + V     +   +A  +  Y    K      +++   G  + G     PL  Y 
Sbjct: 242 MQYVKIKDVARGRLLILMEARLSALY----KLESDYEILERFPGAYLKGKKYR-PLFDYF 296

Query: 371 V-------IYVLPMLTIKEDKGTGVVTSVPSDSPDDIAALRDLKKKQALRAKYGIRDDMV 423
           +         VL    +KE++GTGVV   P    +D     D                 +
Sbjct: 297 LKCKENGAFTVLVDNYVKEEEGTGVVHQAPYFGAEDYRVCMDFN---------------I 341

Query: 424 LPFEPVPVIEIPGFGNLSAVTICDELKIQSQNDREKLAEAKEKIYLKGFYEGIMLVDGFK 483
           +  + +PV  +   G  +                                     V  F 
Sbjct: 342 IRKDSLPVCPVDASGCFTTE-----------------------------------VTDFA 366

Query: 484 GQKVQDVKKTIQKKMIDAGDALIY--MEPEKQVMSRSSDECVVALCDQWYLDYGEENWKK 541
           GQ V+D  K+I + + + G  L+            RS    +      W++       + 
Sbjct: 367 GQYVKDADKSIIRTLKEQGRLLVATTFTHSYPFCWRSDTPLIYKAVPSWFVRV-----EN 421

Query: 542 QTSQCLKNLETFCEETRRNFEATLG-WLQEH---ACSRTYGLGTHLPWDEQWLIESLSDS 597
              Q L+N +          E   G WL++      SR    GT +P    W+ +   + 
Sbjct: 422 MVDQLLRNNDLCYWVPELVREKRFGNWLKDARDWTISRNRYWGTPIPL---WVSDDFEE- 477

Query: 598 TIYMAFYTVAHL--LQGG---NLHGQAESPLGIRPQQMTK-------EVWDYVFFKEAPF 645
              +   +VA L  L G    +LH ++   L I P +  K       EV+D  +F+    
Sbjct: 478 --VVCIGSVAELEELSGAKISDLHRESVDHLTI-PSRCGKGSLHRISEVFD-CWFESGSM 533

Query: 646 PKTQIAKEKLDQLKQEFEFWYPVDLRVSGKDLVPNHLSYYLYNHVAMWPEQSDKWPTAVR 705
           P  Q+      + K+EFE  +P D    G D         L    A++ +   K    V 
Sbjct: 534 PYAQVHYPF--ENKREFEDAFPADFIAEGIDQTRGWFYTLLVLATALFGQPPFK---NVI 588

Query: 706 ANGHLLLNS-EKMSKSTGNFLTLTQAIDKFSADGMRLALADA 746
            NG +L +  +KMSK   N+      I K+ AD +RL L ++
Sbjct: 589 VNGLVLASDGQKMSKRKKNYPDPVSIIQKYGADALRLYLINS 630


>gi|21269877 cysteinyl-tRNA synthetase isoform a [Homo sapiens]
          Length = 726

 Score = 38.9 bits (89), Expect = 0.029
 Identities = 27/75 (36%), Positives = 37/75 (49%), Gaps = 2/75 (2%)

Query: 668 VDLRVSGKDLVPNHLSYYLYNHVAMWPEQSDKWPTAVRANGHLLLNSEKMSKSTGNFLTL 727
           +D+   G DL   H    L    A +  ++D W       GHL +   KMSKS  NF+T+
Sbjct: 360 MDIHGGGFDLRFPHHDNELAQSEAYF--ENDCWVRYFLHTGHLTIAGCKMSKSLKNFITI 417

Query: 728 TQAIDKFSADGMRLA 742
             A+ K SA  +RLA
Sbjct: 418 KDALKKHSARQLRLA 432


>gi|62240994 cysteinyl-tRNA synthetase isoform d [Homo sapiens]
          Length = 738

 Score = 38.9 bits (89), Expect = 0.029
 Identities = 27/75 (36%), Positives = 37/75 (49%), Gaps = 2/75 (2%)

Query: 668 VDLRVSGKDLVPNHLSYYLYNHVAMWPEQSDKWPTAVRANGHLLLNSEKMSKSTGNFLTL 727
           +D+   G DL   H    L    A +  ++D W       GHL +   KMSKS  NF+T+
Sbjct: 350 MDIHGGGFDLRFPHHDNELAQSEAYF--ENDCWVRYFLHTGHLTIAGCKMSKSLKNFITI 407

Query: 728 TQAIDKFSADGMRLA 742
             A+ K SA  +RLA
Sbjct: 408 KDALKKHSARQLRLA 422


>gi|62240992 cysteinyl-tRNA synthetase isoform c [Homo sapiens]
          Length = 831

 Score = 38.9 bits (89), Expect = 0.029
 Identities = 27/75 (36%), Positives = 37/75 (49%), Gaps = 2/75 (2%)

Query: 668 VDLRVSGKDLVPNHLSYYLYNHVAMWPEQSDKWPTAVRANGHLLLNSEKMSKSTGNFLTL 727
           +D+   G DL   H    L    A +  ++D W       GHL +   KMSKS  NF+T+
Sbjct: 443 MDIHGGGFDLRFPHHDNELAQSEAYF--ENDCWVRYFLHTGHLTIAGCKMSKSLKNFITI 500

Query: 728 TQAIDKFSADGMRLA 742
             A+ K SA  +RLA
Sbjct: 501 KDALKKHSARQLRLA 515


>gi|10835051 cysteinyl-tRNA synthetase isoform b [Homo sapiens]
          Length = 748

 Score = 38.9 bits (89), Expect = 0.029
 Identities = 27/75 (36%), Positives = 37/75 (49%), Gaps = 2/75 (2%)

Query: 668 VDLRVSGKDLVPNHLSYYLYNHVAMWPEQSDKWPTAVRANGHLLLNSEKMSKSTGNFLTL 727
           +D+   G DL   H    L    A +  ++D W       GHL +   KMSKS  NF+T+
Sbjct: 360 MDIHGGGFDLRFPHHDNELAQSEAYF--ENDCWVRYFLHTGHLTIAGCKMSKSLKNFITI 417

Query: 728 TQAIDKFSADGMRLA 742
             A+ K SA  +RLA
Sbjct: 418 KDALKKHSARQLRLA 432


>gi|55741845 valyl-tRNA synthetase 2, mitochondrial [Homo sapiens]
          Length = 1063

 Score = 33.1 bits (74), Expect = 1.6
 Identities = 19/80 (23%), Positives = 36/80 (45%)

Query: 24  WDTERVFEVNASNLEKQTSKGKYFVTFPYPYMNGRLHLGHTFSLSKCEFAVGYQRLKGKC 83
           W  E  F+        Q +   + +  P P + G LH+GH  +++  +  V + R++G  
Sbjct: 117 WVREGFFKPEYQARLPQATGETFSMCIPPPNVTGSLHIGHALTVAIQDALVRWHRMRGDQ 176

Query: 84  CLFPFGLHCTGMPIKACADK 103
            L+  G    G+  +A  +K
Sbjct: 177 VLWVPGSDHAGIATQAVVEK 196


>gi|13375695 cysteinyl-tRNA synthetase 2, mitochondrial [Homo
           sapiens]
          Length = 564

 Score = 32.3 bits (72), Expect = 2.7
 Identities = 26/82 (31%), Positives = 37/82 (45%), Gaps = 10/82 (12%)

Query: 664 FWYPVDLRVSGKDLV-PNHLSYYLYNHVAMWP--EQSDKWPTAVRANGHLLLNS--EKMS 718
           F   +D+   G DL  P+H      N +A      Q ++W      +GHL      EKMS
Sbjct: 265 FGSQLDIHSGGIDLAFPHH-----ENEIAQCEVFHQCEQWGNYFLHSGHLHAKGKEEKMS 319

Query: 719 KSTGNFLTLTQAIDKFSADGMR 740
           KS  N++T+   +  FS D  R
Sbjct: 320 KSLKNYITIKDFLKTFSPDVFR 341


>gi|51599156 chromodomain helicase DNA binding protein 4 [Homo
           sapiens]
          Length = 1912

 Score = 32.0 bits (71), Expect = 3.6
 Identities = 23/68 (33%), Positives = 31/68 (45%), Gaps = 3/68 (4%)

Query: 114 PPDFPDEEEEEEETSVKTEDIIIKDKAKGKK---SKAAAKAGSSKYQWGIMKSLGLSDEE 170
           PP  P+ EE+ EE   +TE   +K K K KK    K        K +  + + LG S  E
Sbjct: 29  PPPHPENEEDPEEDLSETETPKLKKKKKPKKPRDPKIPKSKRQKKERMLLCRQLGDSSGE 88

Query: 171 IVKFSEAE 178
             +F E E
Sbjct: 89  GPEFVEEE 96


>gi|190194423 SPARC-like 1 [Homo sapiens]
          Length = 664

 Score = 32.0 bits (71), Expect = 3.6
 Identities = 33/119 (27%), Positives = 55/119 (46%), Gaps = 9/119 (7%)

Query: 119 DEEEEEEETSVKTEDIIIK--DKAKGKKSKAAAKAGSSKYQWGIMKSLGLSDEEIVKFSE 176
           + EE E+ET+V TED      +K+   KSK  +   S++      + LGL D+E      
Sbjct: 48  EAEENEKETAVSTEDDSHHKAEKSSVLKSKEESHEQSAEQGKSSSQELGLKDQEDSDGHL 107

Query: 177 AEHWLDYFPPLAIQDLKR-----MGLKVDWRRSFITTDVNPYYDSFVRWQFLTLRERNK 230
           + + L+Y P     D+K         K+     F+   V+ + DS  + + +T RE N+
Sbjct: 108 SVN-LEYAPTEGTLDIKEDMSEPQEKKLSENTDFLAPGVSSFTDS-NQQESITKREENQ 164


>gi|190341024 SPARC-like 1 [Homo sapiens]
          Length = 664

 Score = 32.0 bits (71), Expect = 3.6
 Identities = 33/119 (27%), Positives = 55/119 (46%), Gaps = 9/119 (7%)

Query: 119 DEEEEEEETSVKTEDIIIK--DKAKGKKSKAAAKAGSSKYQWGIMKSLGLSDEEIVKFSE 176
           + EE E+ET+V TED      +K+   KSK  +   S++      + LGL D+E      
Sbjct: 48  EAEENEKETAVSTEDDSHHKAEKSSVLKSKEESHEQSAEQGKSSSQELGLKDQEDSDGHL 107

Query: 177 AEHWLDYFPPLAIQDLKR-----MGLKVDWRRSFITTDVNPYYDSFVRWQFLTLRERNK 230
           + + L+Y P     D+K         K+     F+   V+ + DS  + + +T RE N+
Sbjct: 108 SVN-LEYAPTEGTLDIKEDMSEPQEKKLSENTDFLAPGVSSFTDS-NQQESITKREENQ 164


>gi|48255891 protein kinase C substrate 80K-H isoform 2 [Homo
           sapiens]
          Length = 525

 Score = 31.6 bits (70), Expect = 4.7
 Identities = 22/71 (30%), Positives = 33/71 (46%), Gaps = 3/71 (4%)

Query: 114 PPDFPDEEEEEEETSVKTEDIIIKDKAKGKKSKAAAKAGSSK---YQWGIMKSLGLSDEE 170
           P +  +EEEEEEE   + E+     + +G++ K A+ A   K   Y       +  + E 
Sbjct: 311 PTEEEEEEEEEEEEEAEEEEEEEDSEVQGEQPKPASPAEEDKMPPYDEQTQAFIDAAQEA 370

Query: 171 IVKFSEAEHWL 181
             KF EAE  L
Sbjct: 371 RNKFEEAERSL 381


>gi|134142826 pericentriolar material 1 [Homo sapiens]
          Length = 2024

 Score = 31.6 bits (70), Expect = 4.7
 Identities = 24/84 (28%), Positives = 44/84 (52%), Gaps = 5/84 (5%)

Query: 90   LHCTGMPIKACADKLKREIELYGCPP---DFPDEEEEEEETSVKTEDIIIKDKAKGKKSK 146
            +  TG+ I++CA + KR +E +G P    D  D++++E ET  +T+   + D  K  +S 
Sbjct: 1708 IEATGV-IQSCAKEAKRILEDHGSPAGEIDDEDKDKDETETVKQTQTSEVYDGPKNVRSD 1766

Query: 147  AAAKAGSSKYQWGIMKSLGLSDEE 170
             + +    + + G   S+ LS  E
Sbjct: 1767 ISDQEEDEESE-GCPVSINLSKAE 1789


>gi|157266334 tubby like protein 1 [Homo sapiens]
          Length = 542

 Score = 31.6 bits (70), Expect = 4.7
 Identities = 18/44 (40%), Positives = 23/44 (52%)

Query: 105 KREIELYGCPPDFPDEEEEEEETSVKTEDIIIKDKAKGKKSKAA 148
           K+ ++  G P     EEEEEEE +   +    K KAKGK  K A
Sbjct: 233 KKALKKKGTPKGARKEEEEEEEAATVIKKSNQKGKAKGKGKKKA 276


>gi|55770834 centromere protein F [Homo sapiens]
          Length = 3114

 Score = 31.2 bits (69), Expect = 6.1
 Identities = 59/237 (24%), Positives = 100/237 (42%), Gaps = 32/237 (13%)

Query: 437 FGNLSAVTICDELKIQSQNDREKLAEAKEKIYLKGFYEGIMLVDGFKGQ--KVQDVKKTI 494
           F N S+  + D+LK Q+Q  R K+ E   ++ L+G  + +      KGQ  K Q+++  +
Sbjct: 271 FDNSSSPHLLDQLKAQNQELRNKINEL--ELRLQGHEKEM------KGQVNKFQELQLQL 322

Query: 495 QKKMIDAGDALIYMEPEKQVMSRSSDECV--VALCDQWYLDYGEENWKKQTSQCLKNLET 552
           +K  ++       +E EK V+++  DE V   A  DQ    Y          Q LK L  
Sbjct: 323 EKAKVE------LIEKEK-VLNKCRDELVRTTAQYDQASTKY------TALEQKLKKLTE 369

Query: 553 FCEETRRNFEATLGWLQEHACSRTYGLGTHLPWDEQWLIESLSDSTIYMAFYTVAHLLQG 612
                R+N E+    L++    +       L   +Q   ++L    I M       L Q 
Sbjct: 370 DLSCQRQNAESARCSLEQKIKEKEKEFQEELS-RQQRSFQTLDQECIQMKARLTQELQQA 428

Query: 613 GNLHG--QAE-SPLGIRPQQMTKEVWDY---VFFKEAPFPKTQIAKEKLDQLKQEFE 663
            N+H   QAE   L    QQ+   + ++   +   E  F  +QI + +L +  +E +
Sbjct: 429 KNMHNVLQAELDKLTSVKQQLENNLEEFKQKLCRAEQAFQASQIKENELRRSMEEMK 485


>gi|187936946 hypothetical protein LOC84140 [Homo sapiens]
          Length = 660

 Score = 30.8 bits (68), Expect = 7.9
 Identities = 20/64 (31%), Positives = 36/64 (56%), Gaps = 5/64 (7%)

Query: 121 EEEEEETSVKTEDIIIKDKAKGKKSKAAAKAGSSKYQWGIMKSLGLSDEEIVKFSEAEHW 180
           E EE E  +K   ++ +  A+ K ++ AA+    K+    +K+LG+SDE + K  ++   
Sbjct: 541 ELEEREEKLKKRPLLFERVAQ-KNARMAAE----KHYSNTLKALGISDEFVSKKGQSGKV 595

Query: 181 LDYF 184
           L+YF
Sbjct: 596 LEYF 599


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.136    0.410 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 45,194,182
Number of Sequences: 37866
Number of extensions: 2084009
Number of successful extensions: 6383
Number of sequences better than 10.0: 21
Number of HSP's better than 10.0 without gapping: 11
Number of HSP's successfully gapped in prelim test: 10
Number of HSP's that attempted gapping in prelim test: 6327
Number of HSP's gapped (non-prelim): 50
length of query: 1176
length of database: 18,247,518
effective HSP length: 113
effective length of query: 1063
effective length of database: 13,968,660
effective search space: 14848685580
effective search space used: 14848685580
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.