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Search of human proteins with 4557707
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4557707 L1 cell adhesion molecule isoform 1 precursor [Homo
sapiens]
(1257 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4557707 L1 cell adhesion molecule isoform 1 precursor [Homo s... 2579 0.0
gi|13435353 L1 cell adhesion molecule isoform 2 precursor [Homo ... 2566 0.0
gi|221316760 L1 cell adhesion molecule isoform 3 precursor [Homo... 2546 0.0
gi|81158226 neuronal cell adhesion molecule isoform A precursor ... 912 0.0
gi|27894376 cell adhesion molecule with homology to L1CAM precur... 827 0.0
gi|81158224 neuronal cell adhesion molecule isoform B precursor ... 763 0.0
gi|237858679 neurofascin isoform 3 precursor [Homo sapiens] 724 0.0
gi|89903008 neurofascin isoform 4 precursor [Homo sapiens] 724 0.0
gi|237858677 neurofascin isoform 2 precursor [Homo sapiens] 716 0.0
gi|237858675 neurofascin isoform 1 precursor [Homo sapiens] 620 e-177
gi|237858682 neurofascin isoform 6 precursor [Homo sapiens] 452 e-126
gi|237858680 neurofascin isoform 5 precursor [Homo sapiens] 452 e-126
gi|75709184 contactin 3 [Homo sapiens] 409 e-113
gi|7657359 contactin 5 isoform long [Homo sapiens] 404 e-112
gi|28373129 contactin 5 isoform short [Homo sapiens] 404 e-112
gi|4827022 contactin 2 precursor [Homo sapiens] 386 e-107
gi|7657361 contactin 6 [Homo sapiens] 379 e-105
gi|28373122 contactin 4 isoform a precursor [Homo sapiens] 377 e-104
gi|28373117 contactin 1 isoform 1 precursor [Homo sapiens] 345 2e-94
gi|28373119 contactin 1 isoform 2 precursor [Homo sapiens] 345 2e-94
gi|28373126 contactin 4 isoform c precursor [Homo sapiens] 259 1e-68
gi|119220552 sidekick 1 [Homo sapiens] 258 2e-68
gi|222352127 sidekick 2 [Homo sapiens] 248 3e-65
gi|20127422 Down syndrome cell adhesion molecule isoform CHD2-42... 243 6e-64
gi|110431348 deleted in colorectal carcinoma [Homo sapiens] 231 3e-60
gi|157311649 neogenin homolog 1 [Homo sapiens] 229 2e-59
gi|21359935 Down syndrome cell adhesion molecule like 1 [Homo sa... 205 3e-52
gi|4506569 roundabout 1 isoform a [Homo sapiens] 204 6e-52
gi|19743806 roundabout 1 isoform b [Homo sapiens] 203 7e-52
gi|193083163 roundabout, axon guidance receptor, homolog 2 isofo... 201 4e-51
>gi|4557707 L1 cell adhesion molecule isoform 1 precursor [Homo
sapiens]
Length = 1257
Score = 2579 bits (6684), Expect = 0.0
Identities = 1257/1257 (100%), Positives = 1257/1257 (100%)
Query: 1 MVVALRYVWPLLLCSPCLLIQIPEEYEGHHVMEPPVITEQSPRRLVVFPTDDISLKCEAS 60
MVVALRYVWPLLLCSPCLLIQIPEEYEGHHVMEPPVITEQSPRRLVVFPTDDISLKCEAS
Sbjct: 1 MVVALRYVWPLLLCSPCLLIQIPEEYEGHHVMEPPVITEQSPRRLVVFPTDDISLKCEAS 60
Query: 61 GKPEVQFRWTRDGVHFKPKEELGVTVYQSPHSGSFTITGNNSNFAQRFQGIYRCFASNKL 120
GKPEVQFRWTRDGVHFKPKEELGVTVYQSPHSGSFTITGNNSNFAQRFQGIYRCFASNKL
Sbjct: 61 GKPEVQFRWTRDGVHFKPKEELGVTVYQSPHSGSFTITGNNSNFAQRFQGIYRCFASNKL 120
Query: 121 GTAMSHEIRLMAEGAPKWPKETVKPVEVEEGESVVLPCNPPPSAEPLRIYWMNSKILHIK 180
GTAMSHEIRLMAEGAPKWPKETVKPVEVEEGESVVLPCNPPPSAEPLRIYWMNSKILHIK
Sbjct: 121 GTAMSHEIRLMAEGAPKWPKETVKPVEVEEGESVVLPCNPPPSAEPLRIYWMNSKILHIK 180
Query: 181 QDERVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLRVKATNSMIDRKP 240
QDERVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLRVKATNSMIDRKP
Sbjct: 181 QDERVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLRVKATNSMIDRKP 240
Query: 241 RLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLL 300
RLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLL
Sbjct: 241 RLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLL 300
Query: 301 KVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRP 360
KVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRP
Sbjct: 301 KVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRP 360
Query: 361 QPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIY 420
QPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIY
Sbjct: 361 QPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIY 420
Query: 421 VVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANG 480
VVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANG
Sbjct: 421 VVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANG 480
Query: 481 TLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQ 540
TLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQ
Sbjct: 481 TLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQ 540
Query: 541 ASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVV 600
ASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVV
Sbjct: 541 ASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVV 600
Query: 601 ESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAEDHNAPIEKYDIEFEDKEMAPE 660
ESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAEDHNAPIEKYDIEFEDKEMAPE
Sbjct: 601 ESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAEDHNAPIEKYDIEFEDKEMAPE 660
Query: 661 KWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAINKYGPGEPSPVSETVVTPEAAPEKNPVD 720
KWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAINKYGPGEPSPVSETVVTPEAAPEKNPVD
Sbjct: 661 KWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAINKYGPGEPSPVSETVVTPEAAPEKNPVD 720
Query: 721 VKGEGNETTNMVITWKPLRWMDWNAPQVQYRVQWRPQGTRGPWQEQIVSDPFLVVSNTST 780
VKGEGNETTNMVITWKPLRWMDWNAPQVQYRVQWRPQGTRGPWQEQIVSDPFLVVSNTST
Sbjct: 721 VKGEGNETTNMVITWKPLRWMDWNAPQVQYRVQWRPQGTRGPWQEQIVSDPFLVVSNTST 780
Query: 781 FVPYEIKVQAVNSQGKGPEPQVTIGYSGEDYPQAIPELEGIEILNSSAVLVKWRPVDLAQ 840
FVPYEIKVQAVNSQGKGPEPQVTIGYSGEDYPQAIPELEGIEILNSSAVLVKWRPVDLAQ
Sbjct: 781 FVPYEIKVQAVNSQGKGPEPQVTIGYSGEDYPQAIPELEGIEILNSSAVLVKWRPVDLAQ 840
Query: 841 VKGHLRGYNVTYWREGSQRKHSKRHIHKDHVVVPANTTSVILSGLRPYSSYHLEVQAFNG 900
VKGHLRGYNVTYWREGSQRKHSKRHIHKDHVVVPANTTSVILSGLRPYSSYHLEVQAFNG
Sbjct: 841 VKGHLRGYNVTYWREGSQRKHSKRHIHKDHVVVPANTTSVILSGLRPYSSYHLEVQAFNG 900
Query: 901 RGSGPASEFTFSTPEGVPGHPEALHLECQSNTSLLLRWQPPLSHNGVLTGYVLSYHPLDE 960
RGSGPASEFTFSTPEGVPGHPEALHLECQSNTSLLLRWQPPLSHNGVLTGYVLSYHPLDE
Sbjct: 901 RGSGPASEFTFSTPEGVPGHPEALHLECQSNTSLLLRWQPPLSHNGVLTGYVLSYHPLDE 960
Query: 961 GGKGQLSFNLRDPELRTHNLTDLSPHLRYRFQLQATTKEGPGEAIVREGGTMALSGISDF 1020
GGKGQLSFNLRDPELRTHNLTDLSPHLRYRFQLQATTKEGPGEAIVREGGTMALSGISDF
Sbjct: 961 GGKGQLSFNLRDPELRTHNLTDLSPHLRYRFQLQATTKEGPGEAIVREGGTMALSGISDF 1020
Query: 1021 GNISATAGENYSVVSWVPKEGQCNFRFHILFKALGEEKGGASLSPQYVSYNQSSYTQWDL 1080
GNISATAGENYSVVSWVPKEGQCNFRFHILFKALGEEKGGASLSPQYVSYNQSSYTQWDL
Sbjct: 1021 GNISATAGENYSVVSWVPKEGQCNFRFHILFKALGEEKGGASLSPQYVSYNQSSYTQWDL 1080
Query: 1081 QPDTDYEIHLFKERMFRHQMAVKTNGTGRVRLPPAGFATEGWFIGFVSAIILLLLVLLIL 1140
QPDTDYEIHLFKERMFRHQMAVKTNGTGRVRLPPAGFATEGWFIGFVSAIILLLLVLLIL
Sbjct: 1081 QPDTDYEIHLFKERMFRHQMAVKTNGTGRVRLPPAGFATEGWFIGFVSAIILLLLVLLIL 1140
Query: 1141 CFIKRSKGGKYSVKDKEDTQVDSEARPMKDETFGEYRSLESDNEEKAFGSSQPSLNGDIK 1200
CFIKRSKGGKYSVKDKEDTQVDSEARPMKDETFGEYRSLESDNEEKAFGSSQPSLNGDIK
Sbjct: 1141 CFIKRSKGGKYSVKDKEDTQVDSEARPMKDETFGEYRSLESDNEEKAFGSSQPSLNGDIK 1200
Query: 1201 PLGSDDSLADYGGSVDVQFNEDGSFIGQYSGKKEKEAAGGNDSSGATSPINPAVALE 1257
PLGSDDSLADYGGSVDVQFNEDGSFIGQYSGKKEKEAAGGNDSSGATSPINPAVALE
Sbjct: 1201 PLGSDDSLADYGGSVDVQFNEDGSFIGQYSGKKEKEAAGGNDSSGATSPINPAVALE 1257
>gi|13435353 L1 cell adhesion molecule isoform 2 precursor [Homo
sapiens]
Length = 1253
Score = 2566 bits (6651), Expect = 0.0
Identities = 1253/1257 (99%), Positives = 1253/1257 (99%), Gaps = 4/1257 (0%)
Query: 1 MVVALRYVWPLLLCSPCLLIQIPEEYEGHHVMEPPVITEQSPRRLVVFPTDDISLKCEAS 60
MVVALRYVWPLLLCSPCLLIQIPEEYEGHHVMEPPVITEQSPRRLVVFPTDDISLKCEAS
Sbjct: 1 MVVALRYVWPLLLCSPCLLIQIPEEYEGHHVMEPPVITEQSPRRLVVFPTDDISLKCEAS 60
Query: 61 GKPEVQFRWTRDGVHFKPKEELGVTVYQSPHSGSFTITGNNSNFAQRFQGIYRCFASNKL 120
GKPEVQFRWTRDGVHFKPKEELGVTVYQSPHSGSFTITGNNSNFAQRFQGIYRCFASNKL
Sbjct: 61 GKPEVQFRWTRDGVHFKPKEELGVTVYQSPHSGSFTITGNNSNFAQRFQGIYRCFASNKL 120
Query: 121 GTAMSHEIRLMAEGAPKWPKETVKPVEVEEGESVVLPCNPPPSAEPLRIYWMNSKILHIK 180
GTAMSHEIRLMAEGAPKWPKETVKPVEVEEGESVVLPCNPPPSAEPLRIYWMNSKILHIK
Sbjct: 121 GTAMSHEIRLMAEGAPKWPKETVKPVEVEEGESVVLPCNPPPSAEPLRIYWMNSKILHIK 180
Query: 181 QDERVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLRVKATNSMIDRKP 240
QDERVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLRVKATNSMIDRKP
Sbjct: 181 QDERVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLRVKATNSMIDRKP 240
Query: 241 RLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLL 300
RLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLL
Sbjct: 241 RLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLL 300
Query: 301 KVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRP 360
KVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRP
Sbjct: 301 KVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRP 360
Query: 361 QPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIY 420
QPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIY
Sbjct: 361 QPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIY 420
Query: 421 VVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANG 480
VVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANG
Sbjct: 421 VVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANG 480
Query: 481 TLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQ 540
TLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQ
Sbjct: 481 TLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQ 540
Query: 541 ASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVV 600
ASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVV
Sbjct: 541 ASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVV 600
Query: 601 ESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAEDHNAPIEKYDIEFEDKEMAPE 660
ESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAEDHNAPIEKYDIEFEDKEMAPE
Sbjct: 601 ESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAEDHNAPIEKYDIEFEDKEMAPE 660
Query: 661 KWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAINKYGPGEPSPVSETVVTPEAAPEKNPVD 720
KWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAINKYGPGEPSPVSETVVTPEAAPEKNPVD
Sbjct: 661 KWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAINKYGPGEPSPVSETVVTPEAAPEKNPVD 720
Query: 721 VKGEGNETTNMVITWKPLRWMDWNAPQVQYRVQWRPQGTRGPWQEQIVSDPFLVVSNTST 780
VKGEGNETTNMVITWKPLRWMDWNAPQVQYRVQWRPQGTRGPWQEQIVSDPFLVVSNTST
Sbjct: 721 VKGEGNETTNMVITWKPLRWMDWNAPQVQYRVQWRPQGTRGPWQEQIVSDPFLVVSNTST 780
Query: 781 FVPYEIKVQAVNSQGKGPEPQVTIGYSGEDYPQAIPELEGIEILNSSAVLVKWRPVDLAQ 840
FVPYEIKVQAVNSQGKGPEPQVTIGYSGEDYPQAIPELEGIEILNSSAVLVKWRPVDLAQ
Sbjct: 781 FVPYEIKVQAVNSQGKGPEPQVTIGYSGEDYPQAIPELEGIEILNSSAVLVKWRPVDLAQ 840
Query: 841 VKGHLRGYNVTYWREGSQRKHSKRHIHKDHVVVPANTTSVILSGLRPYSSYHLEVQAFNG 900
VKGHLRGYNVTYWREGSQRKHSKRHIHKDHVVVPANTTSVILSGLRPYSSYHLEVQAFNG
Sbjct: 841 VKGHLRGYNVTYWREGSQRKHSKRHIHKDHVVVPANTTSVILSGLRPYSSYHLEVQAFNG 900
Query: 901 RGSGPASEFTFSTPEGVPGHPEALHLECQSNTSLLLRWQPPLSHNGVLTGYVLSYHPLDE 960
RGSGPASEFTFSTPEGVPGHPEALHLECQSNTSLLLRWQPPLSHNGVLTGYVLSYHPLDE
Sbjct: 901 RGSGPASEFTFSTPEGVPGHPEALHLECQSNTSLLLRWQPPLSHNGVLTGYVLSYHPLDE 960
Query: 961 GGKGQLSFNLRDPELRTHNLTDLSPHLRYRFQLQATTKEGPGEAIVREGGTMALSGISDF 1020
GGKGQLSFNLRDPELRTHNLTDLSPHLRYRFQLQATTKEGPGEAIVREGGTMALSGISDF
Sbjct: 961 GGKGQLSFNLRDPELRTHNLTDLSPHLRYRFQLQATTKEGPGEAIVREGGTMALSGISDF 1020
Query: 1021 GNISATAGENYSVVSWVPKEGQCNFRFHILFKALGEEKGGASLSPQYVSYNQSSYTQWDL 1080
GNISATAGENYSVVSWVPKEGQCNFRFHILFKALGEEKGGASLSPQYVSYNQSSYTQWDL
Sbjct: 1021 GNISATAGENYSVVSWVPKEGQCNFRFHILFKALGEEKGGASLSPQYVSYNQSSYTQWDL 1080
Query: 1081 QPDTDYEIHLFKERMFRHQMAVKTNGTGRVRLPPAGFATEGWFIGFVSAIILLLLVLLIL 1140
QPDTDYEIHLFKERMFRHQMAVKTNGTGRVRLPPAGFATEGWFIGFVSAIILLLLVLLIL
Sbjct: 1081 QPDTDYEIHLFKERMFRHQMAVKTNGTGRVRLPPAGFATEGWFIGFVSAIILLLLVLLIL 1140
Query: 1141 CFIKRSKGGKYSVKDKEDTQVDSEARPMKDETFGEYRSLESDNEEKAFGSSQPSLNGDIK 1200
CFIKRSKGGKYSVKDKEDTQVDSEARPMKDETFGEY SDNEEKAFGSSQPSLNGDIK
Sbjct: 1141 CFIKRSKGGKYSVKDKEDTQVDSEARPMKDETFGEY----SDNEEKAFGSSQPSLNGDIK 1196
Query: 1201 PLGSDDSLADYGGSVDVQFNEDGSFIGQYSGKKEKEAAGGNDSSGATSPINPAVALE 1257
PLGSDDSLADYGGSVDVQFNEDGSFIGQYSGKKEKEAAGGNDSSGATSPINPAVALE
Sbjct: 1197 PLGSDDSLADYGGSVDVQFNEDGSFIGQYSGKKEKEAAGGNDSSGATSPINPAVALE 1253
>gi|221316760 L1 cell adhesion molecule isoform 3 precursor [Homo
sapiens]
Length = 1248
Score = 2546 bits (6598), Expect = 0.0
Identities = 1247/1257 (99%), Positives = 1248/1257 (99%), Gaps = 9/1257 (0%)
Query: 1 MVVALRYVWPLLLCSPCLLIQIPEEYEGHHVMEPPVITEQSPRRLVVFPTDDISLKCEAS 60
MVVALRYVWPLLLCSPCLLIQIPEE +MEPPVITEQSPRRLVVFPTDDISLKCEAS
Sbjct: 1 MVVALRYVWPLLLCSPCLLIQIPEE-----LMEPPVITEQSPRRLVVFPTDDISLKCEAS 55
Query: 61 GKPEVQFRWTRDGVHFKPKEELGVTVYQSPHSGSFTITGNNSNFAQRFQGIYRCFASNKL 120
GKPEVQFRWTRDGVHFKPKEELGVTVYQSPHSGSFTITGNNSNFAQRFQGIYRCFASNKL
Sbjct: 56 GKPEVQFRWTRDGVHFKPKEELGVTVYQSPHSGSFTITGNNSNFAQRFQGIYRCFASNKL 115
Query: 121 GTAMSHEIRLMAEGAPKWPKETVKPVEVEEGESVVLPCNPPPSAEPLRIYWMNSKILHIK 180
GTAMSHEIRLMAEGAPKWPKETVKPVEVEEGESVVLPCNPPPSAEPLRIYWMNSKILHIK
Sbjct: 116 GTAMSHEIRLMAEGAPKWPKETVKPVEVEEGESVVLPCNPPPSAEPLRIYWMNSKILHIK 175
Query: 181 QDERVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLRVKATNSMIDRKP 240
QDERVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLRVKATNSMIDRKP
Sbjct: 176 QDERVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLRVKATNSMIDRKP 235
Query: 241 RLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLL 300
RLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLL
Sbjct: 236 RLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLL 295
Query: 301 KVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRP 360
KVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRP
Sbjct: 296 KVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRP 355
Query: 361 QPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIY 420
QPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIY
Sbjct: 356 QPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIY 415
Query: 421 VVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANG 480
VVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANG
Sbjct: 416 VVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANG 475
Query: 481 TLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQ 540
TLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQ
Sbjct: 476 TLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQ 535
Query: 541 ASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVV 600
ASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVV
Sbjct: 536 ASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVV 595
Query: 601 ESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAEDHNAPIEKYDIEFEDKEMAPE 660
ESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAEDHNAPIEKYDIEFEDKEMAPE
Sbjct: 596 ESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAEDHNAPIEKYDIEFEDKEMAPE 655
Query: 661 KWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAINKYGPGEPSPVSETVVTPEAAPEKNPVD 720
KWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAINKYGPGEPSPVSETVVTPEAAPEKNPVD
Sbjct: 656 KWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAINKYGPGEPSPVSETVVTPEAAPEKNPVD 715
Query: 721 VKGEGNETTNMVITWKPLRWMDWNAPQVQYRVQWRPQGTRGPWQEQIVSDPFLVVSNTST 780
VKGEGNETTNMVITWKPLRWMDWNAPQVQYRVQWRPQGTRGPWQEQIVSDPFLVVSNTST
Sbjct: 716 VKGEGNETTNMVITWKPLRWMDWNAPQVQYRVQWRPQGTRGPWQEQIVSDPFLVVSNTST 775
Query: 781 FVPYEIKVQAVNSQGKGPEPQVTIGYSGEDYPQAIPELEGIEILNSSAVLVKWRPVDLAQ 840
FVPYEIKVQAVNSQGKGPEPQVTIGYSGEDYPQAIPELEGIEILNSSAVLVKWRPVDLAQ
Sbjct: 776 FVPYEIKVQAVNSQGKGPEPQVTIGYSGEDYPQAIPELEGIEILNSSAVLVKWRPVDLAQ 835
Query: 841 VKGHLRGYNVTYWREGSQRKHSKRHIHKDHVVVPANTTSVILSGLRPYSSYHLEVQAFNG 900
VKGHLRGYNVTYWREGSQRKHSKRHIHKDHVVVPANTTSVILSGLRPYSSYHLEVQAFNG
Sbjct: 836 VKGHLRGYNVTYWREGSQRKHSKRHIHKDHVVVPANTTSVILSGLRPYSSYHLEVQAFNG 895
Query: 901 RGSGPASEFTFSTPEGVPGHPEALHLECQSNTSLLLRWQPPLSHNGVLTGYVLSYHPLDE 960
RGSGPASEFTFSTPEGVPGHPEALHLECQSNTSLLLRWQPPLSHNGVLTGYVLSYHPLDE
Sbjct: 896 RGSGPASEFTFSTPEGVPGHPEALHLECQSNTSLLLRWQPPLSHNGVLTGYVLSYHPLDE 955
Query: 961 GGKGQLSFNLRDPELRTHNLTDLSPHLRYRFQLQATTKEGPGEAIVREGGTMALSGISDF 1020
GGKGQLSFNLRDPELRTHNLTDLSPHLRYRFQLQATTKEGPGEAIVREGGTMALSGISDF
Sbjct: 956 GGKGQLSFNLRDPELRTHNLTDLSPHLRYRFQLQATTKEGPGEAIVREGGTMALSGISDF 1015
Query: 1021 GNISATAGENYSVVSWVPKEGQCNFRFHILFKALGEEKGGASLSPQYVSYNQSSYTQWDL 1080
GNISATAGENYSVVSWVPKEGQCNFRFHILFKALGEEKGGASLSPQYVSYNQSSYTQWDL
Sbjct: 1016 GNISATAGENYSVVSWVPKEGQCNFRFHILFKALGEEKGGASLSPQYVSYNQSSYTQWDL 1075
Query: 1081 QPDTDYEIHLFKERMFRHQMAVKTNGTGRVRLPPAGFATEGWFIGFVSAIILLLLVLLIL 1140
QPDTDYEIHLFKERMFRHQMAVKTNGTGRVRLPPAGFATEGWFIGFVSAIILLLLVLLIL
Sbjct: 1076 QPDTDYEIHLFKERMFRHQMAVKTNGTGRVRLPPAGFATEGWFIGFVSAIILLLLVLLIL 1135
Query: 1141 CFIKRSKGGKYSVKDKEDTQVDSEARPMKDETFGEYRSLESDNEEKAFGSSQPSLNGDIK 1200
CFIKRSKGGKYSVKDKEDTQVDSEARPMKDETFGEY SDNEEKAFGSSQPSLNGDIK
Sbjct: 1136 CFIKRSKGGKYSVKDKEDTQVDSEARPMKDETFGEY----SDNEEKAFGSSQPSLNGDIK 1191
Query: 1201 PLGSDDSLADYGGSVDVQFNEDGSFIGQYSGKKEKEAAGGNDSSGATSPINPAVALE 1257
PLGSDDSLADYGGSVDVQFNEDGSFIGQYSGKKEKEAAGGNDSSGATSPINPAVALE
Sbjct: 1192 PLGSDDSLADYGGSVDVQFNEDGSFIGQYSGKKEKEAAGGNDSSGATSPINPAVALE 1248
>gi|81158226 neuronal cell adhesion molecule isoform A precursor [Homo
sapiens]
Length = 1304
Score = 912 bits (2356), Expect = 0.0
Identities = 507/1291 (39%), Positives = 733/1291 (56%), Gaps = 63/1291 (4%)
Query: 11 LLLCSPCLLIQIPEEYEG-HHVMEPPVITEQSPRRLVVFPTDDISLKCEASGKPEVQFRW 69
L LC +++P + + +++PP IT+QSP+ ++ P ++I ++CEA GKP F W
Sbjct: 21 LFLCQMISALEVPLDPKLLEDLVQPPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSW 80
Query: 70 TRDGVHFKPKEELGVTVYQSPHSGSFTITGNNSNFAQRFQGIYRCFASNKLGTAMSHEIR 129
TR+G HF ++ VT+ P +G+ I + A+ ++G+Y+C A N+ G A+S+ I
Sbjct: 81 TRNGTHFDIDKDPLVTM--KPGTGTLIINIMSEGKAETYEGVYQCTARNERGAAVSNNIV 138
Query: 130 LMAEGAPKWPKETVKPVEVEEGESVVLPCNPPPSAEPLRIYWMNSKILHIKQDERVTMGQ 189
+ +P W KE ++P+ ++ G+S+VLPC PP P I+WM++ + Q ERV+ G
Sbjct: 139 VRPSRSPLWTKEKLEPITLQSGQSLVLPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGL 198
Query: 190 NGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLRVKATNSMID------------ 237
NG+LYF+NVL D DYIC+A F T+TI QK+PI ++V + + + D
Sbjct: 199 NGDLYFSNVLPEDTREDYICYARFNHTQTIQQKQPISVKVISVDELNDTIAANLSDTEFY 258
Query: 238 -------RKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTY 290
R P L P ++S+ L+G L LECIAEG PTP I W + G +P +R Y
Sbjct: 259 GAKSSRERPPTFLTPEGNASNKEELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVY 318
Query: 291 QNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETA 350
+N KTLQ++ V E D G Y+C+A+N+LG+ H V V+AAPYW+ PQ+ + PGE
Sbjct: 319 KNFEKTLQIIHVSEADSGNYQCIAKNALGAIHHTISVRVKAAPYWITAPQNLVLSPGEDG 378
Query: 351 RLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRH 410
L C+ G P+P ++W NG+P+E D +I +I SNVQ + V QC A N +
Sbjct: 379 TLICRANGNPKPRISWLTNGVPIEIAPDDPSRKIDGDTIIFSNVQERSSAVYQCNASNEY 438
Query: 411 GLLLANAYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQ 470
G LLANA++ V+ P +ILT N Y + A L C FG+P+P+++W + L
Sbjct: 439 GYLLANAFVNVLAEPPRILTPANTLYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSALH 498
Query: 471 DERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEK 530
++ + + NGTL I Q + TG Y C+A N +L++KD T I + P + +
Sbjct: 499 EDIYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDPTWIVKQPEYAVVQ 558
Query: 531 KGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYS 590
+GS V+F C+ D +L ++ W D R EL +++ ++ LV+ + D G Y+
Sbjct: 559 RGSMVSFECKVKHDHTLSLTVLWLKDNR---ELPSDERFTVDKDHLVVADVSDDDSGTYT 615
Query: 591 CVASTELDVVESRAQLLVVGSPGPVPRLVLS------DLHLLTQ--SQVRVSWSPAEDHN 642
CVA+T LD V + A L VV +P P P V DL L Q V++SW+P +D+N
Sbjct: 616 CVANTTLDSVSASAVLSVV-APTPTPAPVYDVPNPPFDLELTDQLDKSVQLSWTPGDDNN 674
Query: 643 APIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAINKYGPGEPSP 702
+PI K+ IE+ED P W+ +V G QT+ LKLSPYV+Y+FRV A+N G PS
Sbjct: 675 SPITKFIIEYEDAMHKPGLWHHQTEVSGTQTTAQLKLSPYVNYSFRVMAVNSIGKSLPSE 734
Query: 703 VSETVVTPEAAPEKNPVDVKGEGNETTNMVITWKPLRWMDWNAPQVQYRVQWRPQGTRGP 762
SE +T + P+KNP V+G G+E N+VITWKPL + N P +QY+V WR +
Sbjct: 735 ASEQYLTKASEPDKNPTAVEGLGSEPDNLVITWKPLNGFESNGPGLQYKVSWRQKDGDDE 794
Query: 763 WQEQIVSD-PFLVVSNTSTFVPYEIKVQAVNSQGKGPEPQVTIGYSGEDYPQAIPELEGI 821
W +V++ +VS T TFVPY IKVQA+N G PEP V +G+SGED P P +
Sbjct: 795 WTSVVVANVSKYIVSGTPTFVPYLIKVQALNDMGFAPEPAVVMGHSGEDLPMVAPGNVRV 854
Query: 822 EILNSSAVLVKWRPVDLAQVKGHLRGYNVTYWREGSQRKHSKRHIHKDHVVVPANTTSVI 881
++NS+ V W PV L ++GHL+GY + YW+ S K ++RHI K + + T +
Sbjct: 855 NVVNSTLAEVHWDPVPLKSIRGHLQGYRIYYWKTQSSSKRNRRHIEKKILTFQGSKTHGM 914
Query: 882 LSGLRPYSSYHLEVQAFNGRGSGPAS-EFTFSTPEGVPGHPEALHLECQSNTSLLLRWQP 940
L GL P+S Y L V+ NG+G GPAS + F+TPEGVP P +L + + SL L W P
Sbjct: 915 LPGLEPFSHYTLNVRVVNGKGEGPASPDRVFNTPEGVPSAPSSLKIVNPTLDSLTLEWDP 974
Query: 941 PLSHNGVLTGYVLSYHPLDEGGKGQLSFNLRDPELRTH-NLTDLSPHLRYRFQLQATTKE 999
P NG+LT Y L Y P++ + +L+ P +T L +L+ RY+F A T
Sbjct: 975 PSHPNGILTEYTLKYQPINSTHELGPLVDLKIPANKTRWTLKNLNFSTRYKFYFYAQTSA 1034
Query: 1000 GPGEAIVREG-GTMALSGI--SDFG------------NISATAGENYSVVSWVPKEGQCN 1044
G G I E T+ +GI D G N++A A E Y+ +SW EG +
Sbjct: 1035 GSGSQITEEAVTTVDEAGILPPDVGAGKVQAVNPRISNLTAAAAETYANISW-EYEGPEH 1093
Query: 1045 FRFHILFKALGEEKGGASLSPQYVSYNQSSYTQWDLQPDTDYEIHL--FKERMFRHQMAV 1102
F++ + G ++ + V+ ++S + L P T Y++ + + F V
Sbjct: 1094 VNFYVEYGVAGSKE---EWRKEIVNGSRSFFGLKGLMPGTAYKVRVGAVGDSGFVSSEDV 1150
Query: 1103 KTNGTGRVRLPPAGFATEGWFIGFVSAIILLLLVLLILCFIKRSKGGKYSVKDKEDTQVD 1162
G + AT+GWFIG + A+ LL+L+LLI+CFI+R+KGGKY VK+KED D
Sbjct: 1151 FETGPA-MASRQVDIATQGWFIGLMCAVALLILILLIVCFIRRNKGGKYPVKEKEDAHAD 1209
Query: 1163 SEARPMK--DETFGEYRSLESDNEEKAFGSSQPSLNGDIKPLGSDDSLADYGGSVDVQFN 1220
E +PMK D TFGEY E D++ GS PS + +K SDDSL DYG V+ QFN
Sbjct: 1210 PEIQPMKEDDGTFGEYSDAE-DHKPLKKGSRTPS-DRTVKKEDSDDSLVDYGEGVNGQFN 1267
Query: 1221 EDGSFIGQYSGKKEKEAAGGNDSSGATSPIN 1251
EDGSFIGQYSGKKEKE A GN+SS A SP+N
Sbjct: 1268 EDGSFIGQYSGKKEKEPAEGNESSEAPSPVN 1298
>gi|27894376 cell adhesion molecule with homology to L1CAM precursor
[Homo sapiens]
Length = 1224
Score = 827 bits (2137), Expect = 0.0
Identities = 479/1263 (37%), Positives = 680/1263 (53%), Gaps = 97/1263 (7%)
Query: 20 IQIPEEYEGHHVMEPPVITEQSPRRLVVFPTDD-ISLKCEASGKPEVQFRWTRDGVHFKP 78
I+IP V + P I +QS + V FP D+ ++CEA G PE F WT+DG F
Sbjct: 25 IEIPSS-----VQQVPTIIKQSKVQ-VAFPFDEYFQIECEAKGNPEPTFSWTKDGNPFYF 78
Query: 79 KEELGVTVYQSPHSGSFTITGNNSNFAQRFQGIYRCFASNKLGTAMSHEIRLMAEGAPKW 138
+ + S +SG+F I N FQG YRCFASNKLG AMS EI + PK+
Sbjct: 79 TDH---RIIPSNNSGTFRIP--NEGHISHFQGKYRCFASNKLGIAMSEEIEFIVPSVPKF 133
Query: 139 PKETVKPVEVEEGESVVLPCNPPPSAEPLRIYWMNSKILHIKQDERVTMGQNGNLYFANV 198
PKE + P+EVEEG+ +VLPCNPP PL IYWMN ++ HI+QDERV M Q G+LYFANV
Sbjct: 134 PKEKIDPLEVEEGDPIVLPCNPPKGLPPLHIYWMNIELEHIEQDERVYMSQKGDLYFANV 193
Query: 199 LTSDNHSDYICHAHFPGTRTIIQKEPIDLRVKA----------------TNSMIDRKPRL 242
D+ +DY C A FP RTI+QK P+ L V + NS+ RKP+L
Sbjct: 194 EEKDSRNDYCCFAAFPRLRTIVQKMPMKLTVNSLKHANDSSSSTEIGSKANSIKQRKPKL 253
Query: 243 LFP---TNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQL 299
L P + S S + L+G+ L+LEC AEG PTP + W + G +P R T +N+ KTL++
Sbjct: 254 LLPPTESGSESSITILKGEILLLECFAEGLPTPQVDWNKIGGDLPKGRETKENYGKTLKI 313
Query: 300 LKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGR 359
V +D G YRC A N LG+A H ++V VE P W KPQS +Y G L C+ +G
Sbjct: 314 ENVSYQDKGNYRCTASNFLGTATHDFHVIVEEPPRWTKKPQSAVYSTGSNGILLCEAEGE 373
Query: 360 PQPEVTWRINGIPVEE--LAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANA 417
PQP + WR+NG PV+ A D + + + +N+QP+ T V QCEA N HG +LANA
Sbjct: 374 PQPTIKWRVNGSPVDNHPFAGDVVFPRE---ISFTNLQPNHTAVYQCEASNVHGTILANA 430
Query: 418 YIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPY 477
I VV + I T D + Y V G +A+L C+ F +P V W + L+ R+ Y
Sbjct: 431 NIDVVDVRPLIQTKDGENYATVVGYSAFLHCEFFASPEAVVSWQKVEEVKPLEGRRYHIY 490
Query: 478 ANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTF 537
NGTL I D G Y C N + ANL +++AT++ P++ K +
Sbjct: 491 ENGTLQINRTTEEDAGSYSCWVENAIGKTAVTANLDIRNATKLRVSPKNPRIPKLHMLEL 550
Query: 538 TCQASFDPSLQPSI--TWRGDGRDLQELGDSDKYFIEDG-RLVIHSLDYSDQGNYSCVAS 594
C++ D L+ S+ +W DG + G D I DG L I ++ DQG Y C A
Sbjct: 551 HCESKCDSHLKHSLKLSWSKDGEAFEINGTEDGRIIIDGANLTISNVTLEDQGIYCCSAH 610
Query: 595 TELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAEDHNAPIEKYDIEFED 654
T LD Q+ V+ P P L LS+ VR++W DHN+ I +Y +EFE
Sbjct: 611 TALDSAADITQVTVLDVPDPPENLHLSERQ---NRSVRLTWEAGADHNSNISEYIVEFEG 667
Query: 655 KEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAINKYGPGEPSPVSETVVTPEAAP 714
+ P +W L +V G +T+ L L+P+V Y FRV A+N+ G +PS S+ TP AAP
Sbjct: 668 NKEEPGRWEELTRVQGKKTTVILPLAPFVRYQFRVIAVNEVGRSQPSQPSDHHETPPAAP 727
Query: 715 EKNPVDVKGEGNETTNMVITWKPLRWMDWNAPQVQYRVQWRPQGTRGPWQEQIVSDPFLV 774
++NP +++ + ++ M+I W+PL+ M+ N P ++YRV W+PQG W+E+ V++ L
Sbjct: 728 DRNPQNIRVQASQPKEMIIKWEPLKSMEQNGPGLEYRVTWKPQGAPVEWEEETVTNHTLR 787
Query: 775 VSNTSTFVPYEIKVQAVNSQGKGPEPQVTIGYSGEDYPQAIPELEGIEILNSSAVLVKWR 834
V + + PY++KVQA+N G GP+PQ YSGEDYP P + G++++NS+ V V W
Sbjct: 788 VMTPAVYAPYDVKVQAINQLGSGPDPQSVTLYSGEDYPDTAPVIHGVDVINSTLVKVTWS 847
Query: 835 PVDLAQVKGHLRGYNVTYWREGSQRKHSKRHIHKDHVVVPANTTSVILSGLRPYSSYHLE 894
V +V G L+GY + +W+ S + + S ++ L +S +HL
Sbjct: 848 TVPKDRVHGRLKGYQINWWKTKSLLDGRTHPKEVNILRFSGQRNSGMVPSLDAFSEFHLT 907
Query: 895 VQAFNGRGSGPASE-FTFSTPEGVPGHPEALHLECQSNTSLLLRWQPPLSHNGVLTGYVL 953
V A+N +G+GP SE + F TPEGVP P L + + L W P NG LTGY+L
Sbjct: 908 VLAYNSKGAGPESEPYIFQTPEGVPEQPTFLKVIKVDKDTATLSWGLPKKLNGNLTGYLL 967
Query: 954 SYHPLDEGGK-GQLS-FNLRDPELRTHNLTDLSPHLRYRFQLQATTKEGPGEAIVREGGT 1011
Y +++ + G+L+ N+ P + +L++L+ +Y+F L+A T +G G+ I E T
Sbjct: 968 QYQIINDTYEIGELNDINITTPSKPSWHLSNLNATTKYKFYLRACTSQGCGKPITEESST 1027
Query: 1012 MALSGISDFGNISATAGENYSVVSWVPKEGQCNFRFHILFKALGEEKGGASLSPQYVSYN 1071
+ G G IS V+
Sbjct: 1028 LG-EGSKGIGKISG------------------------------------------VNLT 1044
Query: 1072 QSSYTQWDLQPDTDYEIHLFKERMFRH----QMAVKTNGTGRVRLPPAGFATEGWFIGFV 1127
Q ++ +P ++ + L + + Q ++T G L +T+GWFIG +
Sbjct: 1045 QKTHPIEVFEPGAEHIVRLMTKNWGDNDSIFQDVIETRGREYAGLYD-DISTQGWFIGLM 1103
Query: 1128 SAIILLLLVLLILCFIKRSKGGKYSVKDKEDTQVDSEARPMKDETFGEYRSLESDNEEKA 1187
AI LL L+LL +CF+KR++GGKYSVK+KED D E + +KDETFGEY SD++EK
Sbjct: 1104 CAIALLTLLLLTVCFVKRNRGGKYSVKEKEDLHPDPEIQSVKDETFGEY----SDSDEKP 1159
Query: 1188 FGSSQPSLNGDIKPLGSDDSLADYGGSVDVQFNEDGSFIGQYSGKKEKEAAGGNDSSGAT 1247
S SLN D++P S DSL +YG F+EDGSFIG Y+G KEK + N SS AT
Sbjct: 1160 LKGSLRSLNRDMQPTESADSLVEYGEGDHGLFSEDGSFIGAYAGSKEKGSVESNGSSTAT 1219
Query: 1248 SPI 1250
P+
Sbjct: 1220 FPL 1222
>gi|81158224 neuronal cell adhesion molecule isoform B precursor [Homo
sapiens]
Length = 1183
Score = 763 bits (1969), Expect = 0.0
Identities = 397/1023 (38%), Positives = 583/1023 (56%), Gaps = 35/1023 (3%)
Query: 11 LLLCSPCLLIQIPEEYEGHHVMEPPVITEQSPRRLVVFPTDDISLKCEASGKPEVQFRWT 70
L LC +++P + +++PP IT+QSP+ ++ P ++I ++CEA GKP F WT
Sbjct: 21 LFLCQMISALEVPLD-----LVQPPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWT 75
Query: 71 RDGVHFKPKEELGVTVYQSPHSGSFTITGNNSNFAQRFQGIYRCFASNKLGTAMSHEIRL 130
R+G HF ++ VT+ P +G+ I + A+ ++G+Y+C A N+ G A+S+ I +
Sbjct: 76 RNGTHFDIDKDPLVTM--KPGTGTLIINIMSEGKAETYEGVYQCTARNERGAAVSNNIVV 133
Query: 131 MAEGAPKWPKETVKPVEVEEGESVVLPCNPPPSAEPLRIYWMNSKILHIKQDERVTMGQN 190
+P W KE ++P+ ++ G+S+VLPC PP P I+WM++ + Q ERV+ G N
Sbjct: 134 RPSRSPLWTKEKLEPITLQSGQSLVLPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGLN 193
Query: 191 GNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLRVKATNSMID------------- 237
G+LYF+NVL D DYIC+A F T+TI QK+PI ++V + + + D
Sbjct: 194 GDLYFSNVLPEDTREDYICYARFNHTQTIQQKQPISVKVISVDELNDTIAANLSDTEFYG 253
Query: 238 ------RKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQ 291
R P L P ++S+ L+G L LECIAEG PTP I W + G +P +R Y+
Sbjct: 254 AKSSRERPPTFLTPEGNASNKEELRGNVLSLECIAEGLPTPIIYWAKEDGMLPKNRTVYK 313
Query: 292 NHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETAR 351
N KTLQ++ V E D G Y+C+A+N+LG+ H V V+AAPYW+ PQ+ + PGE
Sbjct: 314 NFEKTLQIIHVSEADSGNYQCIAKNALGAIHHTISVRVKAAPYWITAPQNLVLSPGEDGT 373
Query: 352 LDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHG 411
L C+ G P+P ++W NG+P+E D +I +I SNVQ + V QC A N +G
Sbjct: 374 LICRANGNPKPRISWLTNGVPIEIAPDDPSRKIDGDTIIFSNVQERSSAVYQCNASNEYG 433
Query: 412 LLLANAYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQD 471
LLANA++ V+ P +ILT N Y + A L C FG+P+P+++W + L +
Sbjct: 434 YLLANAFVNVLAEPPRILTPANTLYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSALHE 493
Query: 472 ERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKK 531
+ + + NGTL I Q + TG Y C+A N +L++KD T I + P + ++
Sbjct: 494 DIYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDPTWIVKQPEYAVVQR 553
Query: 532 GSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSC 591
GS V+F C+ D +L ++ W D R EL +++ ++ LV+ + D G Y+C
Sbjct: 554 GSMVSFECKVKHDHTLSLTVLWLKDNR---ELPSDERFTVDKDHLVVADVSDDDSGTYTC 610
Query: 592 VASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAEDHNAPIEKYDIE 651
VA+T LD V + A L VV P P L L+D V++SW+P +D+N+PI K+ IE
Sbjct: 611 VANTTLDSVSASAVLSVVDVPNPPFDLELTD---QLDKSVQLSWTPGDDNNSPITKFIIE 667
Query: 652 FEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAINKYGPGEPSPVSETVVTPE 711
+ED P W+ +V G QT+ LKLSPYV+Y+FRV A+N G PS SE +T
Sbjct: 668 YEDAMHKPGLWHHQTEVSGTQTTAQLKLSPYVNYSFRVMAVNSIGKSLPSEASEQYLTKA 727
Query: 712 AAPEKNPVDVKGEGNETTNMVITWKPLRWMDWNAPQVQYRVQWRPQGTRGPWQEQIVSD- 770
+ P+KNP V+G G+E N+VITWKPL + N P +QY+V WR + W +V++
Sbjct: 728 SEPDKNPTAVEGLGSEPDNLVITWKPLNGFESNGPGLQYKVSWRQKDGDDEWTSVVVANV 787
Query: 771 PFLVVSNTSTFVPYEIKVQAVNSQGKGPEPQVTIGYSGEDYPQAIPELEGIEILNSSAVL 830
+VS T TFVPY IKVQA+N G PEP V +G+SGED P P + ++NS+
Sbjct: 788 SKYIVSGTPTFVPYLIKVQALNDMGFAPEPAVVMGHSGEDLPMVAPGNVRVNVVNSTLAE 847
Query: 831 VKWRPVDLAQVKGHLRGYNVTYWREGSQRKHSKRHIHKDHVVVPANTTSVILSGLRPYSS 890
V W PV L ++GHL+GY + YW+ S K ++RHI K + + T +L GL P+S
Sbjct: 848 VHWDPVPLKSIRGHLQGYRIYYWKTQSSSKRNRRHIEKKILTFQGSKTHGMLPGLEPFSH 907
Query: 891 YHLEVQAFNGRGSGPAS-EFTFSTPEGVPGHPEALHLECQSNTSLLLRWQPPLSHNGVLT 949
Y L V+ NG+G GPAS + F+TPEGVP P +L + + SL L W PP NG+LT
Sbjct: 908 YTLNVRVVNGKGEGPASPDRVFNTPEGVPSAPSSLKIVNPTLDSLTLEWDPPSHPNGILT 967
Query: 950 GYVLSYHPLDEGGKGQLSFNLRDPELRTH-NLTDLSPHLRYRFQLQATTKEGPGEAIVRE 1008
Y L Y P++ + +L+ P +T L +L+ RY+F A T G G I E
Sbjct: 968 EYTLKYQPINSTHELGPLVDLKIPANKTRWTLKNLNFSTRYKFYFYAQTSAGSGSQITEE 1027
Query: 1009 GGT 1011
T
Sbjct: 1028 AVT 1030
Score = 237 bits (604), Expect = 6e-62
Identities = 306/1211 (25%), Positives = 482/1211 (39%), Gaps = 150/1211 (12%)
Query: 127 EIRLMAEGAPKWPKETVKPVEVEEGESVVLPCNPPPSAEPLRIYWMNSKILHIKQDERVT 186
E+ L P +++ K ++ E++V+ C P + N I +D VT
Sbjct: 31 EVPLDLVQPPTITQQSPKDYIIDPRENIVIQCEAKGKPPPSFSWTRNGTHFDIDKDPLVT 90
Query: 187 MGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLRVKA-TNSMIDRKPRLLFP 245
M N+++ Y + Q + R A +N+++ R R
Sbjct: 91 MKPGTGTLIINIMSEGKAETY---------EGVYQCTARNERGAAVSNNIVVRPSRSPLW 141
Query: 246 TNSSSHLVALQ-GQPLVLECIAE-GFPTPTIKWLRPSGP-MPADRVTYQNHNKTLQLLKV 302
T + LQ GQ LVL C G P P I W+ S +P Q N L V
Sbjct: 142 TKEKLEPITLQSGQSLVLPCRPPIGLPPPIIFWMDNSFQRLPQSERVSQGLNGDLYFSNV 201
Query: 303 GEEDDGE-YRCLAE-NSLGSARHAYYVTVEA---------------------APYWLHKP 339
ED E Y C A N + + ++V+ A +P
Sbjct: 202 LPEDTREDYICYARFNHTQTIQQKQPISVKVISVDELNDTIAANLSDTEFYGAKSSRERP 261
Query: 340 QSHLYGPGETAR----------LDCQVQGRPQPEVTW-RINGIPVEELAKDQK-YRIQRG 387
+ L G + L+C +G P P + W + +G+ L K++ Y+
Sbjct: 262 PTFLTPEGNASNKEELRGNVLSLECIAEGLPTPIIYWAKEDGM----LPKNRTVYKNFEK 317
Query: 388 ALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQTYMAVQGSTAYLL 447
L + +V +D+ QC A+N G + + V P I N + G L+
Sbjct: 318 TLQIIHVSEADSGNYQCIAKNALGAIHHTISVRVKAAPYWITAPQN--LVLSPGEDGTLI 375
Query: 448 CKAFGAPVPSVQWLDED-GTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNV 506
C+A G P P + WL + D+ T+ ++Q + Y C A+N+ +
Sbjct: 376 CRANGNPKPRISWLTNGVPIEIAPDDPSRKIDGDTIIFSNVQERSSAVYQCNASNEYGYL 435
Query: 507 TIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITW--RGDGRDLQELG 564
A + V P +T+ + + +F S P+I W G L E
Sbjct: 436 LANAFVNVLAEPPRILTPANTLYQVIANRPALLDCAFFGSPLPTIEWFKGAKGSALHE-- 493
Query: 565 DSDKYFI-EDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDL 623
D Y + E+G L I G Y+CVA +L + ++ L + +V
Sbjct: 494 --DIYVLHENGTLEIPVAQKDSTGTYTCVARNKLGMAKNEVHLEIKDPTW----IVKQPE 547
Query: 624 HLLTQSQVRVSWSPAEDHNAPIEKYDIEFED-KEMAPEKWYSLGKVPGNQTSTTLKLSPY 682
+ + Q VS+ H+ + + +D +E+ ++ +++ K +S
Sbjct: 548 YAVVQRGSMVSFECKVKHDHTLSLTVLWLKDNRELPSDERFTVDK----DHLVVADVSDD 603
Query: 683 VHYTFRVTAINKYGPGEPSPVSETVVTPEAAPEKNPVDVKGEGNETTNMVITWKPLRWMD 742
T+ A S V V P P D++ ++ ++W P D
Sbjct: 604 DSGTYTCVANTTLDSVSASAVLSVVDVPNP-----PFDLELTDQLDKSVQLSWTP--GDD 656
Query: 743 WNAPQVQYRVQWRPQGTR-GPW--QEQIVSDPFLVVSNTSTFVPYEIKVQAVNSQGKG-- 797
N+P ++ +++ + G W Q ++ S +V Y +V AVNS GK
Sbjct: 657 NNSPITKFIIEYEDAMHKPGLWHHQTEVSGTQTTAQLKLSPYVNYSFRVMAVNSIGKSLP 716
Query: 798 ---PEPQVTIGYSGEDYPQAIPELEGIEILNSSAVLVKWRPVDLAQVKGHLRGYNVTYWR 854
E +T + P A+ L G E N +++ W+P++ + G Y V++ +
Sbjct: 717 SEASEQYLTKASEPDKNPTAVEGL-GSEPDN---LVITWKPLNGFESNGPGLQYKVSWRQ 772
Query: 855 EGSQRKHSKRHIHKDHVVVPANTTSVILSGLRPYSSYHLEVQAFNGRGSGPASEFTFSTP 914
+ + + VV AN + I+SG + Y ++VQA N G P P
Sbjct: 773 KDGDDEWTS--------VVVANVSKYIVSGTPTFVPYLIKVQALNDMGFAPE-------P 817
Query: 915 EGVPGH---------PEALHLECQSNTSLLLRWQP-PL-SHNGVLTGYVLSYHPLDEGGK 963
V GH P + + ++T + W P PL S G L GY + Y K
Sbjct: 818 AVVMGHSGEDLPMVAPGNVRVNVVNSTLAEVHWDPVPLKSIRGHLQGYRIYYWKTQSSSK 877
Query: 964 GQLSFNLRDPELR--------THN-LTDLSPHLRYRFQLQATTKEGPGEAI------VRE 1008
N R E + TH L L P Y ++ +G G A E
Sbjct: 878 R----NRRHIEKKILTFQGSKTHGMLPGLEPFSHYTLNVRVVNGKGEGPASPDRVFNTPE 933
Query: 1009 GGTMALSGISDFGNISATAGENYSVVSWVPKEGQCNF--RFHILFKALGEEKGGASLSPQ 1066
G A S + ++ T + W P + + ++ + L
Sbjct: 934 GVPSAPSSLKI---VNPTLDS--LTLEWDPPSHPNGILTEYTLKYQPINSTHELGPLVDL 988
Query: 1067 YVSYNQSSYTQWDLQPDTDYEIHLFKERMFRHQMAVKTNGTGRVRLPPAG----FATEGW 1122
+ N++ +T +L T Y+ + + + + V A AT+GW
Sbjct: 989 KIPANKTRWTLKNLNFSTRYKFYFYAQTSAGSGSQITEEAVTTVDEAMASRQVDIATQGW 1048
Query: 1123 FIGFVSAIILLLLVLLILCFIKRSKGGKYSVKDKEDTQVDSEARPMK--DETFGEYRSLE 1180
FIG + A+ LL+L+LLI+CFI+R+KGGKY VK+KED D E +PMK D TFGEY E
Sbjct: 1049 FIGLMCAVALLILILLIVCFIRRNKGGKYPVKEKEDAHADPEIQPMKEDDGTFGEYSDAE 1108
Query: 1181 SDNEEKAFGSSQPSLNGDIKPLGSDDSLADYGGSVDVQFNEDGSFIGQYSGKKEKEAAGG 1240
D++ GS PS + +K SDDSL DYG V+ QFNEDGSFIGQYSGKKEKE A G
Sbjct: 1109 -DHKPLKKGSRTPS-DRTVKKEDSDDSLVDYGEGVNGQFNEDGSFIGQYSGKKEKEPAEG 1166
Query: 1241 NDSSGATSPIN 1251
N+SS A SP+N
Sbjct: 1167 NESSEAPSPVN 1177
>gi|237858679 neurofascin isoform 3 precursor [Homo sapiens]
Length = 1174
Score = 724 bits (1870), Expect = 0.0
Identities = 391/1015 (38%), Positives = 556/1015 (54%), Gaps = 36/1015 (3%)
Query: 17 CLL-----IQIPEEYEGHHVMEPPVITEQSPRRLVVFPTDDISLKCEASGKPEVQFRWTR 71
CLL I+IP + + +PP IT+QS + +V P D+I ++CEA G P F WTR
Sbjct: 17 CLLSLGGAIEIPMD-----LTQPPTITKQSAKDHIVDPRDNILIECEAKGNPAPSFHWTR 71
Query: 72 DGVHFKPKEELGVTVYQSPHSGSFTITGNNSNFAQRFQGIYRCFASNKLGTAMSHEIRLM 131
+ F ++ V++ + SG+ I + + ++G Y+CFA NK GTA+S+ IRL
Sbjct: 72 NSRFFNIAKDPRVSMRR--RSGTLVIDFRSGGRPEEYEGEYQCFARNKFGTALSNRIRLQ 129
Query: 132 AEGAPKWPKETVKPVEVEEGESVVLPCNPPPSAEPLRIYWMNSKILHIKQDERVTMGQNG 191
+P WPKE + PV V+EG + L CNPPP I+WM+S + I QD+RV+ G NG
Sbjct: 130 VSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWMSSSMEPITQDKRVSQGHNG 189
Query: 192 NLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLRVKATN-----------------S 234
+LYF+NV+ D +DY C+A F T TI QK P L+V +
Sbjct: 190 DLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVLTNHPYNDSSLRNHPDMYSARG 249
Query: 235 MIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHN 294
+ +R P ++P ++S + L+G L+LECIA G PTP I W + G +P+D+ ++N N
Sbjct: 250 VAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPSDKAKFENFN 309
Query: 295 KTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDC 354
K L++ V EED GEY CLA N +GS RH V V+AAPYWL +P++ + PGE RL C
Sbjct: 310 KALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEPKNLILAPGEDGRLVC 369
Query: 355 QVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLL 414
+ G P+P V W +NG P++ + + +I + Q S V QC N HG LL
Sbjct: 370 RANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCNTSNEHGYLL 429
Query: 415 ANAYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERF 474
ANA++ V+ +P ++L+ NQ + + L C FG+P+P+++W + L +
Sbjct: 430 ANAFVSVLDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNY 489
Query: 475 FPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSR 534
Y NG+L I+ ++ D G Y C+A N L+VKD T+I + P + ++G+
Sbjct: 490 HVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKDPTRIYRMPEDQVARRGTT 549
Query: 535 VTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVAS 594
V C+ DPSL+ +++W D L +G+ K ED L I + DQG+Y+CVAS
Sbjct: 550 VQLECRVKHDPSLKLTVSWLKDDEPLY-IGNRMKK--EDDSLTIFGVAERDQGSYTCVAS 606
Query: 595 TELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAEDHNAPIEKYDIEFED 654
TELD ++A L V+G P L L+D L + VR++W P + +N+PI Y ++FE+
Sbjct: 607 TELDQDLAKAYLTVLGRPDRPRDLELTD---LAERSVRLTWIPGDANNSPITDYVVQFEE 663
Query: 655 KEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAINKYGPGEPSPVSETVVTPEAAP 714
+ P W+ K PG+ S L+LSPYV+Y FRV AIN+ G PS SE T A P
Sbjct: 664 DQFQPGVWHDHSKYPGSVNSAVLRLSPYVNYQFRVIAINEVGSSHPSLPSERYRTSGAPP 723
Query: 715 EKNPVDVKGEGNETTNMVITWKPLRWMDWNAPQVQYRVQWRPQGTRGPWQEQIVSDPFLV 774
E NP DVKGEG NM ITW P+ P ++Y V+WR + TR W V V
Sbjct: 724 ESNPGDVKGEGTRKNNMEITWTPMNATSAFGPNLRYIVKWRRRETREAWNNVTVWGSRYV 783
Query: 775 VSNTSTFVPYEIKVQAVNSQGKGPEPQVTIGYSGEDYPQAIPELEGIEILNSSAVLVKWR 834
V T +VPYEI+VQA N GKGPEP+ IGYSGEDYP+A P + ++NS+A+ ++W
Sbjct: 784 VGQTPVYVPYEIRVQAENDFGKGPEPESVIGYSGEDYPRAAPTEVKVRVMNSTAISLQWN 843
Query: 835 PVDLAQVKGHLRGYNVTYWREGSQRKHSKRHIHKDHVVVPANTTSVILSGLRPYSSYHLE 894
V V+G LR Y YWRE S K+ + P + ++S L PYS+Y LE
Sbjct: 844 RVYSDTVQGQLREYRAYYWRESSLLKNLWVSQKRQQASFPGDRLRGVVSRLFPYSNYKLE 903
Query: 895 VQAFNGRGSGPASEF-TFSTPEGVPGHPEALHLECQSNTSLLLRWQPPLSHNGVLTGYVL 953
+ NGRG GP SE F+TPEGVP P + + ++ L W P NG++ GY L
Sbjct: 904 MVVVNGRGDGPRSETKEFTTPEGVPSAPRRFRVRQPNLETINLEWDHPEHPNGIMIGYTL 963
Query: 954 SYHPLDEGGKGQLSFNLRDPELRTHNLTDLSPHLRYRFQLQATTKEGPGEAIVRE 1008
Y + G+ P + P RYRF L A T+ G GEA+ E
Sbjct: 964 KYVAFNGTKVGKQIVENFSPNQTKFTVQRTDPVSRYRFTLSARTQVGSGEAVTEE 1018
Score = 228 bits (581), Expect = 3e-59
Identities = 299/1204 (24%), Positives = 477/1204 (39%), Gaps = 130/1204 (10%)
Query: 127 EIRLMAEGAPKWPKETVKPVEVEEGESVVLPCNPPPSAEPLRIYWMNSKILHIKQDERVT 186
EI + P K++ K V+ +++++ C + P + NS+ +I +D RV+
Sbjct: 26 EIPMDLTQPPTITKQSAKDHIVDPRDNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVS 85
Query: 187 MGQNGNLYFANVLTS----DNHSDYICHAHFPGTRTIIQKEPIDLRVKATNSMIDRKPRL 242
M + + + + +Y C A + + +R++ + S
Sbjct: 86 MRRRSGTLVIDFRSGGRPEEYEGEYQCFARNKFGTALSNR----IRLQVSKSP------- 134
Query: 243 LFPTNSSSHLVALQGQPLVLECIAE-GFPTPTIKWLRPS-GPMPADRVTYQNHNKTLQLL 300
L+P + +V +G PL L+C G P+P I W+ S P+ D+ Q HN L
Sbjct: 135 LWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWMSSSMEPITQDKRVSQGHNGDLYFS 194
Query: 301 KVGEED-DGEYRCLA-------------------------ENSLGSARHAYYV--TVEAA 332
V +D +Y C A ++SL + Y E
Sbjct: 195 NVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVLTNHPYNDSSLRNHPDMYSARGVAERT 254
Query: 333 PYWLHKPQ----SHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQ-KYRIQRG 387
P +++ PQ S + G L+C G P P++ W G +L D+ K+
Sbjct: 255 PSFMY-PQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKKG---GDLPSDKAKFENFNK 310
Query: 388 ALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQTYMAVQGSTAYLL 447
AL ++NV D+ C A N+ G + + V P + N + G L+
Sbjct: 311 ALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEPKN--LILAPGEDGRLV 368
Query: 448 CKAFGAPVPSVQWLDEDGTTVLQDERFFP---YANGTLGIRDLQANDTGRYFCLAANDQN 504
C+A G P P+VQW+ LQ P A T+ RD Q + Y C +N+
Sbjct: 369 CRANGNPKPTVQWMVNGEP--LQSAPPNPNREVAGDTIIFRDTQISSRAVYQCNTSNEHG 426
Query: 505 NVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELG 564
+ A + V D PR+ + + F S P++ W +G+ L
Sbjct: 427 YLLANAFVSVLDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQG-SNLD 485
Query: 565 DSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLH 624
+ + E+G L I + DQG Y+CVA+ L E++ +L V P + R+ +
Sbjct: 486 GGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRL-EVKDPTRIYRMPEDQVA 544
Query: 625 ---LLTQSQVRVSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTL-KLS 680
Q + RV P+ K D E Y ++ S T+ ++
Sbjct: 545 RRGTTVQLECRVKHDPSLKLTVSWLKDD----------EPLYIGNRMKKEDDSLTIFGVA 594
Query: 681 PYVHYTFRVTAINKYGPGEPSPVSETVVTPEAAPEKNPVDVKGEGNETTNMVITWKPLRW 740
++ A + +++ +T P++ P D++ ++ +TW P
Sbjct: 595 ERDQGSYTCVASTELD----QDLAKAYLTVLGRPDR-PRDLELTDLAERSVRLTWIPGDA 649
Query: 741 MDWNAPQVQYRVQWRP-QGTRGPWQE--QIVSDPFLVVSNTSTFVPYEIKVQAVNSQGKG 797
N+P Y VQ+ Q G W + + V S +V Y+ +V A+N G
Sbjct: 650 N--NSPITDYVVQFEEDQFQPGVWHDHSKYPGSVNSAVLRLSPYVNYQFRVIAINEVGSS 707
Query: 798 PE--PQVTIGYSGEDYPQAIPELEGIEILNSSAVLVKWRPVDLAQVKGHLRGYNVTYWRE 855
P SG P++ P E + + + W P++ G Y V + R
Sbjct: 708 HPSLPSERYRTSGAP-PESNPGDVKGEGTRKNNMEITWTPMNATSAFGPNLRYIVKWRRR 766
Query: 856 GSQRKHSKRHIHKDHVVVPANTTSVILSGLRP-YSSYHLEVQAFN--GRGSGPASEFTFS 912
++ + + VV G P Y Y + VQA N G+G P S +S
Sbjct: 767 ETREAWNNVTVWGSRYVV----------GQTPVYVPYEIRVQAENDFGKGPEPESVIGYS 816
Query: 913 TPEGVPGHPEALHLECQSNTSLLLRWQPPLSHN--GVLTGYVLSYHPLDEGGKGQLSFNL 970
+ P + + ++T++ L+W S G L Y Y K
Sbjct: 817 GEDYPRAAPTEVKVRVMNSTAISLQWNRVYSDTVQGQLREYRAYYWRESSLLKNLWVSQK 876
Query: 971 RD----PELRTHNLTD-LSPHLRYRFQLQATTKEGPGEAIVREGGTMALSGISDFGNISA 1025
R P R + L P+ Y+ ++ G G + T G+
Sbjct: 877 RQQASFPGDRLRGVVSRLFPYSNYKLEMVVVNGRGDGPRSETKEFTTP-EGVPSAPRRFR 935
Query: 1026 TAGENYSVVS--WVPKEGQCNFR--FHILFKALGEEKGGASLSPQYVSYNQSSYTQWDLQ 1081
N ++ W E + + + A K G + + S NQ+ +T
Sbjct: 936 VRQPNLETINLEWDHPEHPNGIMIGYTLKYVAFNGTKVGKQIVENF-SPNQTKFTVQRTD 994
Query: 1082 PDTDYEIHLFKERMFRHQMAV---------KTNGTGRVRLPPAGFATEGWFIGFVSAIIL 1132
P + Y L AV + T A AT+GWFIG + AI L
Sbjct: 995 PVSRYRFTLSARTQVGSGEAVTEESPAPPNEATPTAAYTNNQADIATQGWFIGLMCAIAL 1054
Query: 1133 LLLVLLILCFIKRSKGGKYSVKDKEDTQVDSEARPMKDETFGEYRSLESDNEEKAFGSSQ 1192
L+L+LLI+CFIKRS+GGKY V++K+D + E +D +F +Y SD + K SQ
Sbjct: 1055 LVLILLIVCFIKRSRGGKYPVREKKDVPLGPEDPKEEDGSF-DY----SDEDNKPLQGSQ 1109
Query: 1193 PSLNGDIKPLGSDDSLADYGGSVDVQFNEDGSFIGQYSGKKEKEAAGGNDSSGATSPINP 1252
SL+G IK SDDSL DYG + QFNEDGSFIGQY+ KK+KE GN+SS ATSP+N
Sbjct: 1110 TSLDGTIKQQESDDSLVDYGEGGEGQFNEDGSFIGQYTVKKDKEETEGNESSEATSPVNA 1169
Query: 1253 AVAL 1256
+L
Sbjct: 1170 IYSL 1173
>gi|89903008 neurofascin isoform 4 precursor [Homo sapiens]
Length = 1169
Score = 724 bits (1870), Expect = 0.0
Identities = 391/1015 (38%), Positives = 556/1015 (54%), Gaps = 36/1015 (3%)
Query: 17 CLL-----IQIPEEYEGHHVMEPPVITEQSPRRLVVFPTDDISLKCEASGKPEVQFRWTR 71
CLL I+IP + + +PP IT+QS + +V P D+I ++CEA G P F WTR
Sbjct: 17 CLLSLGGAIEIPMD-----LTQPPTITKQSAKDHIVDPRDNILIECEAKGNPAPSFHWTR 71
Query: 72 DGVHFKPKEELGVTVYQSPHSGSFTITGNNSNFAQRFQGIYRCFASNKLGTAMSHEIRLM 131
+ F ++ V++ + SG+ I + + ++G Y+CFA NK GTA+S+ IRL
Sbjct: 72 NSRFFNIAKDPRVSMRR--RSGTLVIDFRSGGRPEEYEGEYQCFARNKFGTALSNRIRLQ 129
Query: 132 AEGAPKWPKETVKPVEVEEGESVVLPCNPPPSAEPLRIYWMNSKILHIKQDERVTMGQNG 191
+P WPKE + PV V+EG + L CNPPP I+WM+S + I QD+RV+ G NG
Sbjct: 130 VSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWMSSSMEPITQDKRVSQGHNG 189
Query: 192 NLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLRVKATN-----------------S 234
+LYF+NV+ D +DY C+A F T TI QK P L+V +
Sbjct: 190 DLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVLTNHPYNDSSLRNHPDMYSARG 249
Query: 235 MIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHN 294
+ +R P ++P ++S + L+G L+LECIA G PTP I W + G +P+D+ ++N N
Sbjct: 250 VAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPSDKAKFENFN 309
Query: 295 KTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDC 354
K L++ V EED GEY CLA N +GS RH V V+AAPYWL +P++ + PGE RL C
Sbjct: 310 KALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEPKNLILAPGEDGRLVC 369
Query: 355 QVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLL 414
+ G P+P V W +NG P++ + + +I + Q S V QC N HG LL
Sbjct: 370 RANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCNTSNEHGYLL 429
Query: 415 ANAYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERF 474
ANA++ V+ +P ++L+ NQ + + L C FG+P+P+++W + L +
Sbjct: 430 ANAFVSVLDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNY 489
Query: 475 FPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSR 534
Y NG+L I+ ++ D G Y C+A N L+VKD T+I + P + ++G+
Sbjct: 490 HVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKDPTRIYRMPEDQVARRGTT 549
Query: 535 VTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVAS 594
V C+ DPSL+ +++W D L +G+ K ED L I + DQG+Y+CVAS
Sbjct: 550 VQLECRVKHDPSLKLTVSWLKDDEPLY-IGNRMKK--EDDSLTIFGVAERDQGSYTCVAS 606
Query: 595 TELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAEDHNAPIEKYDIEFED 654
TELD ++A L V+G P L L+D L + VR++W P + +N+PI Y ++FE+
Sbjct: 607 TELDQDLAKAYLTVLGRPDRPRDLELTD---LAERSVRLTWIPGDANNSPITDYVVQFEE 663
Query: 655 KEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAINKYGPGEPSPVSETVVTPEAAP 714
+ P W+ K PG+ S L+LSPYV+Y FRV AIN+ G PS SE T A P
Sbjct: 664 DQFQPGVWHDHSKYPGSVNSAVLRLSPYVNYQFRVIAINEVGSSHPSLPSERYRTSGAPP 723
Query: 715 EKNPVDVKGEGNETTNMVITWKPLRWMDWNAPQVQYRVQWRPQGTRGPWQEQIVSDPFLV 774
E NP DVKGEG NM ITW P+ P ++Y V+WR + TR W V V
Sbjct: 724 ESNPGDVKGEGTRKNNMEITWTPMNATSAFGPNLRYIVKWRRRETREAWNNVTVWGSRYV 783
Query: 775 VSNTSTFVPYEIKVQAVNSQGKGPEPQVTIGYSGEDYPQAIPELEGIEILNSSAVLVKWR 834
V T +VPYEI+VQA N GKGPEP+ IGYSGEDYP+A P + ++NS+A+ ++W
Sbjct: 784 VGQTPVYVPYEIRVQAENDFGKGPEPESVIGYSGEDYPRAAPTEVKVRVMNSTAISLQWN 843
Query: 835 PVDLAQVKGHLRGYNVTYWREGSQRKHSKRHIHKDHVVVPANTTSVILSGLRPYSSYHLE 894
V V+G LR Y YWRE S K+ + P + ++S L PYS+Y LE
Sbjct: 844 RVYSDTVQGQLREYRAYYWRESSLLKNLWVSQKRQQASFPGDRLRGVVSRLFPYSNYKLE 903
Query: 895 VQAFNGRGSGPASEF-TFSTPEGVPGHPEALHLECQSNTSLLLRWQPPLSHNGVLTGYVL 953
+ NGRG GP SE F+TPEGVP P + + ++ L W P NG++ GY L
Sbjct: 904 MVVVNGRGDGPRSETKEFTTPEGVPSAPRRFRVRQPNLETINLEWDHPEHPNGIMIGYTL 963
Query: 954 SYHPLDEGGKGQLSFNLRDPELRTHNLTDLSPHLRYRFQLQATTKEGPGEAIVRE 1008
Y + G+ P + P RYRF L A T+ G GEA+ E
Sbjct: 964 KYVAFNGTKVGKQIVENFSPNQTKFTVQRTDPVSRYRFTLSARTQVGSGEAVTEE 1018
Score = 229 bits (584), Expect = 1e-59
Identities = 301/1203 (25%), Positives = 478/1203 (39%), Gaps = 133/1203 (11%)
Query: 127 EIRLMAEGAPKWPKETVKPVEVEEGESVVLPCNPPPSAEPLRIYWMNSKILHIKQDERVT 186
EI + P K++ K V+ +++++ C + P + NS+ +I +D RV+
Sbjct: 26 EIPMDLTQPPTITKQSAKDHIVDPRDNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVS 85
Query: 187 MGQNGNLYFANVLTS----DNHSDYICHAHFPGTRTIIQKEPIDLRVKATNSMIDRKPRL 242
M + + + + +Y C A + + +R++ + S
Sbjct: 86 MRRRSGTLVIDFRSGGRPEEYEGEYQCFARNKFGTALSNR----IRLQVSKSP------- 134
Query: 243 LFPTNSSSHLVALQGQPLVLECIAE-GFPTPTIKWLRPS-GPMPADRVTYQNHNKTLQLL 300
L+P + +V +G PL L+C G P+P I W+ S P+ D+ Q HN L
Sbjct: 135 LWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWMSSSMEPITQDKRVSQGHNGDLYFS 194
Query: 301 KVGEED-DGEYRCLA-------------------------ENSLGSARHAYYV--TVEAA 332
V +D +Y C A ++SL + Y E
Sbjct: 195 NVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVLTNHPYNDSSLRNHPDMYSARGVAERT 254
Query: 333 PYWLHKPQ----SHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQ-KYRIQRG 387
P +++ PQ S + G L+C G P P++ W G +L D+ K+
Sbjct: 255 PSFMY-PQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKKG---GDLPSDKAKFENFNK 310
Query: 388 ALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQTYMAVQGSTAYLL 447
AL ++NV D+ C A N+ G + + V P + N + G L+
Sbjct: 311 ALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEPKN--LILAPGEDGRLV 368
Query: 448 CKAFGAPVPSVQWLDEDGTTVLQDERFFP---YANGTLGIRDLQANDTGRYFCLAANDQN 504
C+A G P P+VQW+ LQ P A T+ RD Q + Y C +N+
Sbjct: 369 CRANGNPKPTVQWMVNGEP--LQSAPPNPNREVAGDTIIFRDTQISSRAVYQCNTSNEHG 426
Query: 505 NVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELG 564
+ A + V D PR+ + + F S P++ W +G+ L
Sbjct: 427 YLLANAFVSVLDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQG-SNLD 485
Query: 565 DSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLH 624
+ + E+G L I + DQG Y+CVA+ L E++ +L V P + R+ +
Sbjct: 486 GGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRL-EVKDPTRIYRMPEDQVA 544
Query: 625 ---LLTQSQVRVSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTL-KLS 680
Q + RV P+ K D E Y ++ S T+ ++
Sbjct: 545 RRGTTVQLECRVKHDPSLKLTVSWLKDD----------EPLYIGNRMKKEDDSLTIFGVA 594
Query: 681 PYVHYTFRVTAINKYGPGEPSPVSETVVTPEAAPEKNPVDVKGEGNETTNMVITWKPLRW 740
++ A + +++ +T P++ P D++ ++ +TW P
Sbjct: 595 ERDQGSYTCVASTELD----QDLAKAYLTVLGRPDR-PRDLELTDLAERSVRLTWIPGDA 649
Query: 741 MDWNAPQVQYRVQWRP-QGTRGPWQE--QIVSDPFLVVSNTSTFVPYEIKVQAVNSQGKG 797
N+P Y VQ+ Q G W + + V S +V Y+ +V A+N G
Sbjct: 650 N--NSPITDYVVQFEEDQFQPGVWHDHSKYPGSVNSAVLRLSPYVNYQFRVIAINEVGSS 707
Query: 798 PE--PQVTIGYSGEDYPQAIPELEGIEILNSSAVLVKWRPVDLAQVKGHLRGYNVTYWRE 855
P SG P++ P E + + + W P++ G Y V + R
Sbjct: 708 HPSLPSERYRTSGAP-PESNPGDVKGEGTRKNNMEITWTPMNATSAFGPNLRYIVKWRRR 766
Query: 856 GSQRKHSKRHIHKDHVVVPANTTSVILSGLRP-YSSYHLEVQAFN--GRGSGPASEFTFS 912
++ + + VV G P Y Y + VQA N G+G P S +S
Sbjct: 767 ETREAWNNVTVWGSRYVV----------GQTPVYVPYEIRVQAENDFGKGPEPESVIGYS 816
Query: 913 TPEGVPGHPEALHLECQSNTSLLLRWQPPLSHN--GVLTGYVLSYHPLDEGGKGQLSFNL 970
+ P + + ++T++ L+W S G L Y Y K
Sbjct: 817 GEDYPRAAPTEVKVRVMNSTAISLQWNRVYSDTVQGQLREYRAYYWRESSLLKNLWVSQK 876
Query: 971 RD----PELRTHNLTD-LSPHLRYRFQLQATTKEGPGEAIVREGGTMALSGISDFGNISA 1025
R P R + L P+ Y+ ++ G G + T G+
Sbjct: 877 RQQASFPGDRLRGVVSRLFPYSNYKLEMVVVNGRGDGPRSETKEFTTP-EGVPSAPRRFR 935
Query: 1026 TAGENYSVVS--WVPKEGQCNFR--FHILFKALGEEKGGASLSPQYVSYNQSSYTQWDLQ 1081
N ++ W E + + + A K G + + S NQ+ +T
Sbjct: 936 VRQPNLETINLEWDHPEHPNGIMIGYTLKYVAFNGTKVGKQIVENF-SPNQTKFTVQRTD 994
Query: 1082 PDTDYEIHLFKERMFRHQMAVKTNGTGRVRLPP--------AGFATEGWFIGFVSAIILL 1133
P + Y L AV T PP A AT+GWFIG + AI LL
Sbjct: 995 PVSRYRFTLSARTQVGSGEAV----TEESPAPPNEAYTNNQADIATQGWFIGLMCAIALL 1050
Query: 1134 LLVLLILCFIKRSKGGKYSVKDKEDTQVDSEARPMKDETFGEYRSLESDNEEKAFGSSQP 1193
+L+LLI+CFIKRS+GGKY V++K+D + E +D +F +Y SD + K SQ
Sbjct: 1051 VLILLIVCFIKRSRGGKYPVREKKDVPLGPEDPKEEDGSF-DY----SDEDNKPLQGSQT 1105
Query: 1194 SLNGDIKPLGSDDSLADYGGSVDVQFNEDGSFIGQYSGKKEKEAAGGNDSSGATSPINPA 1253
SL+G IK SDDSL DYG + QFNEDGSFIGQY+ KK+KE GN+SS ATSP+N
Sbjct: 1106 SLDGTIKQQESDDSLVDYGEGGEGQFNEDGSFIGQYTVKKDKEETEGNESSEATSPVNAI 1165
Query: 1254 VAL 1256
+L
Sbjct: 1166 YSL 1168
>gi|237858677 neurofascin isoform 2 precursor [Homo sapiens]
Length = 1189
Score = 716 bits (1848), Expect = 0.0
Identities = 392/1027 (38%), Positives = 556/1027 (54%), Gaps = 45/1027 (4%)
Query: 17 CLL-----IQIPEEYEGHHVMEPPVITEQSPRRLVVFPTDDISLKCEASGKPEVQFRWTR 71
CLL I+IP + + +PP IT+QS + +V P D+I ++CEA G P F WTR
Sbjct: 17 CLLSLGGAIEIPMD-----LTQPPTITKQSAKDHIVDPRDNILIECEAKGNPAPSFHWTR 71
Query: 72 DGVHFKPKEELGVTVYQSPHSGSFTITGNNSNFAQRFQGIYRCFASNKLGTAMSHEIRLM 131
+ F ++ V++ + SG+ I + + ++G Y+CFA NK GTA+S+ IRL
Sbjct: 72 NSRFFNIAKDPRVSMRR--RSGTLVIDFRSGGRPEEYEGEYQCFARNKFGTALSNRIRLQ 129
Query: 132 AEGAPKWPKETVKPVEVEEGESVVLPCNPPPSAEPLRIYWMNSKILHIKQDERVTMGQNG 191
+P WPKE + PV V+EG + L CNPPP I+WM+S + I QD+RV+ G NG
Sbjct: 130 VSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWMSSSMEPITQDKRVSQGHNG 189
Query: 192 NLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLRVKATN-----------------S 234
+LYF+NV+ D +DY C+A F T TI QK P L+V +
Sbjct: 190 DLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVLTNHPYNDSSLRNHPDMYSARG 249
Query: 235 MIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHN 294
+ +R P ++P ++S + L+G L+LECIA G PTP I W + G +P+D+ ++N N
Sbjct: 250 VAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPSDKAKFENFN 309
Query: 295 KTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDC 354
K L++ V EED GEY CLA N +GS RH V V+AAPYWL +P++ + PGE RL C
Sbjct: 310 KALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEPKNLILAPGEDGRLVC 369
Query: 355 QVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLL 414
+ G P+P V W +NG P++ + + +I + Q S V QC N HG LL
Sbjct: 370 RANGNPKPTVQWMVNGEPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCNTSNEHGYLL 429
Query: 415 ANAYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERF 474
ANA++ V+ +P ++L+ NQ + + L C FG+P+P+++W + L +
Sbjct: 430 ANAFVSVLDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNY 489
Query: 475 FPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSR 534
Y NG+L I+ ++ D G Y C+A N L+VKD T+I + P + ++G+
Sbjct: 490 HVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRLEVKDPTRIYRMPEDQVARRGTT 549
Query: 535 VTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVAS 594
V C+ DPSL+ +++W D L +G+ K ED L I + DQG+Y+CVAS
Sbjct: 550 VQLECRVKHDPSLKLTVSWLKDDEPLY-IGNRMKK--EDDSLTIFGVAERDQGSYTCVAS 606
Query: 595 TELDVVESRAQLLVVGSPG-PVPRLVL---------SDLHL--LTQSQVRVSWSPAEDHN 642
TELD ++A L V+ P RL DL L L + VR++W P + +N
Sbjct: 607 TELDQDLAKAYLTVLADQATPTNRLAALPKGRPDRPRDLELTDLAERSVRLTWIPGDANN 666
Query: 643 APIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAINKYGPGEPSP 702
+PI Y ++FE+ + P W+ K PG+ S L+LSPYV+Y FRV AIN+ G PS
Sbjct: 667 SPITDYVVQFEEDQFQPGVWHDHSKYPGSVNSAVLRLSPYVNYQFRVIAINEVGSSHPSL 726
Query: 703 VSETVVTPEAAPEKNPVDVKGEGNETTNMVITWKPLRWMDWNAPQVQYRVQWRPQGTRGP 762
SE T A PE NP DVKGEG NM ITW P+ P ++Y V+WR + TR
Sbjct: 727 PSERYRTSGAPPESNPGDVKGEGTRKNNMEITWTPMNATSAFGPNLRYIVKWRRRETREA 786
Query: 763 WQEQIVSDPFLVVSNTSTFVPYEIKVQAVNSQGKGPEPQVTIGYSGEDYPQAIPELEGIE 822
W V VV T +VPYEI+VQA N GKGPEP+ IGYSGEDYP+A P +
Sbjct: 787 WNNVTVWGSRYVVGQTPVYVPYEIRVQAENDFGKGPEPESVIGYSGEDYPRAAPTEVKVR 846
Query: 823 ILNSSAVLVKWRPVDLAQVKGHLRGYNVTYWREGSQRKHSKRHIHKDHVVVPANTTSVIL 882
++NS+A+ ++W V V+G LR Y YWRE S K+ + P + ++
Sbjct: 847 VMNSTAISLQWNRVYSDTVQGQLREYRAYYWRESSLLKNLWVSQKRQQASFPGDRLRGVV 906
Query: 883 SGLRPYSSYHLEVQAFNGRGSGPASEF-TFSTPEGVPGHPEALHLECQSNTSLLLRWQPP 941
S L PYS+Y LE+ NGRG GP SE F+TPEGVP P + + ++ L W P
Sbjct: 907 SRLFPYSNYKLEMVVVNGRGDGPRSETKEFTTPEGVPSAPRRFRVRQPNLETINLEWDHP 966
Query: 942 LSHNGVLTGYVLSYHPLDEGGKGQLSFNLRDPELRTHNLTDLSPHLRYRFQLQATTKEGP 1001
NG++ GY L Y + G+ P + P RYRF L A T+ G
Sbjct: 967 EHPNGIMIGYTLKYVAFNGTKVGKQIVENFSPNQTKFTVQRTDPVSRYRFTLSARTQVGS 1026
Query: 1002 GEAIVRE 1008
GEA+ E
Sbjct: 1027 GEAVTEE 1033
Score = 235 bits (600), Expect = 2e-61
Identities = 302/1206 (25%), Positives = 477/1206 (39%), Gaps = 119/1206 (9%)
Query: 127 EIRLMAEGAPKWPKETVKPVEVEEGESVVLPCNPPPSAEPLRIYWMNSKILHIKQDERVT 186
EI + P K++ K V+ +++++ C + P + NS+ +I +D RV+
Sbjct: 26 EIPMDLTQPPTITKQSAKDHIVDPRDNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVS 85
Query: 187 MGQNGNLYFANVLTS----DNHSDYICHAHFPGTRTIIQKEPIDLRVKATNSMIDRKPRL 242
M + + + + +Y C A + + +R++ + S
Sbjct: 86 MRRRSGTLVIDFRSGGRPEEYEGEYQCFARNKFGTALSNR----IRLQVSKSP------- 134
Query: 243 LFPTNSSSHLVALQGQPLVLECIAE-GFPTPTIKWLRPS-GPMPADRVTYQNHNKTLQLL 300
L+P + +V +G PL L+C G P+P I W+ S P+ D+ Q HN L
Sbjct: 135 LWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWMSSSMEPITQDKRVSQGHNGDLYFS 194
Query: 301 KVGEED-DGEYRCLA-------------------------ENSLGSARHAYYV--TVEAA 332
V +D +Y C A ++SL + Y E
Sbjct: 195 NVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVLTNHPYNDSSLRNHPDMYSARGVAERT 254
Query: 333 PYWLHKPQ----SHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQ-KYRIQRG 387
P +++ PQ S + G L+C G P P++ W G +L D+ K+
Sbjct: 255 PSFMY-PQGTASSQMVLRGMDLLLECIASGVPTPDIAWYKKG---GDLPSDKAKFENFNK 310
Query: 388 ALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQTYMAVQGSTAYLL 447
AL ++NV D+ C A N+ G + + V P + N + G L+
Sbjct: 311 ALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAPYWLDEPKN--LILAPGEDGRLV 368
Query: 448 CKAFGAPVPSVQWLDEDGTTVLQDERFFP---YANGTLGIRDLQANDTGRYFCLAANDQN 504
C+A G P P+VQW+ LQ P A T+ RD Q + Y C +N+
Sbjct: 369 CRANGNPKPTVQWMVNGEP--LQSAPPNPNREVAGDTIIFRDTQISSRAVYQCNTSNEHG 426
Query: 505 NVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELG 564
+ A + V D PR+ + + F S P++ W +G+ L
Sbjct: 427 YLLANAFVSVLDVPPRMLSPRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQG-SNLD 485
Query: 565 DSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLH 624
+ + E+G L I + DQG Y+CVA+ L E++ +L V P + R+ +
Sbjct: 486 GGNYHVYENGSLEIKMIRKEDQGIYTCVATNILGKAENQVRL-EVKDPTRIYRMPEDQVA 544
Query: 625 ---LLTQSQVRVSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSL---GKVPGNQTSTTLK 678
Q + RV P+ K D ++ SL G +Q S T
Sbjct: 545 RRGTTVQLECRVKHDPSLKLTVSWLKDDEPLYIGNRMKKEDDSLTIFGVAERDQGSYTCV 604
Query: 679 LSPYVHYTFRVTAINKYGPGEPSPVSETVVTPEAAPEKNPVDVKGEGNETTNMVITWKPL 738
S + + + +P + P+ P++ P D++ ++ +TW P
Sbjct: 605 ASTELDQDLAKAYLTVLAD-QATPTNRLAALPKGRPDR-PRDLELTDLAERSVRLTWIPG 662
Query: 739 RWMDWNAPQVQYRVQWRP-QGTRGPWQE--QIVSDPFLVVSNTSTFVPYEIKVQAVNSQG 795
N+P Y VQ+ Q G W + + V S +V Y+ +V A+N G
Sbjct: 663 DAN--NSPITDYVVQFEEDQFQPGVWHDHSKYPGSVNSAVLRLSPYVNYQFRVIAINEVG 720
Query: 796 KGPE--PQVTIGYSGEDYPQAIPELEGIEILNSSAVLVKWRPVDLAQVKGHLRGYNVTYW 853
P SG P++ P E + + + W P++ G Y V +
Sbjct: 721 SSHPSLPSERYRTSGAP-PESNPGDVKGEGTRKNNMEITWTPMNATSAFGPNLRYIVKWR 779
Query: 854 REGSQRKHSKRHIHKDHVVVPANTTSVILSGLRP-YSSYHLEVQAFN--GRGSGPASEFT 910
R ++ + + VV G P Y Y + VQA N G+G P S
Sbjct: 780 RRETREAWNNVTVWGSRYVV----------GQTPVYVPYEIRVQAENDFGKGPEPESVIG 829
Query: 911 FSTPEGVPGHPEALHLECQSNTSLLLRWQPPLSHN--GVLTGYVLSYHPLDEGGKGQLSF 968
+S + P + + ++T++ L+W S G L Y Y K
Sbjct: 830 YSGEDYPRAAPTEVKVRVMNSTAISLQWNRVYSDTVQGQLREYRAYYWRESSLLKNLWVS 889
Query: 969 NLRD----PELRTHNLTD-LSPHLRYRFQLQATTKEGPGEAIVREGGTMALSGISDFGNI 1023
R P R + L P+ Y+ ++ G G + T G+
Sbjct: 890 QKRQQASFPGDRLRGVVSRLFPYSNYKLEMVVVNGRGDGPRSETKEFTTP-EGVPSAPRR 948
Query: 1024 SATAGENYSVVS--WVPKEGQCNFR--FHILFKALGEEKGGASLSPQYVSYNQSSYTQWD 1079
N ++ W E + + + A K G + + S NQ+ +T
Sbjct: 949 FRVRQPNLETINLEWDHPEHPNGIMIGYTLKYVAFNGTKVGKQIVENF-SPNQTKFTVQR 1007
Query: 1080 LQPDTDYEIHLFKERMFRHQMAV---------KTNGTGRVRLPPAGFATEGWFIGFVSAI 1130
P + Y L AV + T A AT+GWFIG + AI
Sbjct: 1008 TDPVSRYRFTLSARTQVGSGEAVTEESPAPPNEATPTAAYTNNQADIATQGWFIGLMCAI 1067
Query: 1131 ILLLLVLLILCFIKRSKGGKYSVKDKEDTQVDSEARPMKDETFGEYRSLESDNEEKAFGS 1190
LL+L+LLI+CFIKRS+GGKY V++K+D + E +D +F +Y SD + K
Sbjct: 1068 ALLVLILLIVCFIKRSRGGKYPVREKKDVPLGPEDPKEEDGSF-DY----SDEDNKPLQG 1122
Query: 1191 SQPSLNGDIKPLGSDDSLADYGGSVDVQFNEDGSFIGQYSGKKEKEAAGGNDSSGATSPI 1250
SQ SL+G IK SDDSL DYG + QFNEDGSFIGQY+ KK+KE GN+SS ATSP+
Sbjct: 1123 SQTSLDGTIKQQESDDSLVDYGEGGEGQFNEDGSFIGQYTVKKDKEETEGNESSEATSPV 1182
Query: 1251 NPAVAL 1256
N +L
Sbjct: 1183 NAIYSL 1188
>gi|237858675 neurofascin isoform 1 precursor [Homo sapiens]
Length = 1240
Score = 620 bits (1599), Expect = e-177
Identities = 345/908 (37%), Positives = 492/908 (54%), Gaps = 31/908 (3%)
Query: 17 CLL-----IQIPEEYE-GHHVMEPPVITEQSPRRLVVFPTDDISLKCEASGKPEVQFRWT 70
CLL I+IP + + + +PP IT+QS + +V P D+I ++CEA G P F WT
Sbjct: 17 CLLSLGGAIEIPMDPSIQNELTQPPTITKQSAKDHIVDPRDNILIECEAKGNPAPSFHWT 76
Query: 71 RDGVHFKPKEELGVTVYQSPHSGSFTITGNNSNFAQRFQGIYRCFASNKLGTAMSHEIRL 130
R+ F ++ V++ + SG+ I + + ++G Y+CFA NK GTA+S+ IRL
Sbjct: 77 RNSRFFNIAKDPRVSMRR--RSGTLVIDFRSGGRPEEYEGEYQCFARNKFGTALSNRIRL 134
Query: 131 MAEGAPKWPKETVKPVEVEEGESVVLPCNPPPSAEPLRIYWMNSKILHIKQDERVTMGQN 190
+P WPKE + PV V+EG + L CNPPP I+WM+S + I QD+RV+ G N
Sbjct: 135 QVSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWMSSSMEPITQDKRVSQGHN 194
Query: 191 GNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSS 250
G+LYF+NV+ D +DY C+A F T TI QK P L+V T + +R P ++P ++S
Sbjct: 195 GDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVLTTRGVAERTPSFMYPQGTAS 254
Query: 251 HLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEY 310
+ L+G L+LECIA G PTP I W + G +P+D+ ++N NK L++ V EED GEY
Sbjct: 255 SQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPSDKAKFENFNKALRITNVSEEDSGEY 314
Query: 311 RCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRING 370
CLA N +GS RH V V+AAPYWL +P++ + PGE RL C+ G P+P V W +NG
Sbjct: 315 FCLASNKMGSIRHTISVRVKAAPYWLDEPKNLILAPGEDGRLVCRANGNPKPTVQWMVNG 374
Query: 371 IPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILT 430
P++ + + +I + Q S V QC N HG LLANA++ V+ +P ++L+
Sbjct: 375 EPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCNTSNEHGYLLANAFVSVLDVPPRMLS 434
Query: 431 ADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQAN 490
NQ + + L C FG+P+P+++W + L + Y NG+L I+ ++
Sbjct: 435 PRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGSLEIKMIRKE 494
Query: 491 DTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPS 550
D G Y C+A N L+VKD T+I + P + ++G+ V C+ DPSL+ +
Sbjct: 495 DQGIYTCVATNILGKAENQVRLEVKDPTRIYRMPEDQVARRGTTVQLECRVKHDPSLKLT 554
Query: 551 ITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVG 610
++W D L +G+ K ED L I + DQG+Y+CVASTELD ++A L V+
Sbjct: 555 VSWLKDDEPLY-IGNRMKK--EDDSLTIFGVAERDQGSYTCVASTELDQDLAKAYLTVLA 611
Query: 611 SPG-PVPRLVL---------SDLHL--LTQSQVRVSWSPAEDHNAPIEKYDIEFEDKEMA 658
P RL DL L L + VR++W P + +N+PI Y ++FE+ +
Sbjct: 612 DQATPTNRLAALPKGRPDRPRDLELTDLAERSVRLTWIPGDANNSPITDYVVQFEEDQFQ 671
Query: 659 PEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAINKYGPGEPSPVSETVVTPEAAPEKNP 718
P W+ K PG+ S L+LSPYV+Y FRV AIN+ G PS SE T A PE NP
Sbjct: 672 PGVWHDHSKYPGSVNSAVLRLSPYVNYQFRVIAINEVGSSHPSLPSERYRTSGAPPESNP 731
Query: 719 VDVKGEGNETTNMVITWKPLRWMDWNAPQVQYRVQWRPQGTRGPWQEQIVSDPFLVVSNT 778
DVKGEG NM ITW P+ P ++Y V+WR + TR W V VV T
Sbjct: 732 GDVKGEGTRKNNMEITWTPMNATSAFGPNLRYIVKWRRRETREAWNNVTVWGSRYVVGQT 791
Query: 779 STFVPYEIKVQAVNSQGKGPEPQVTIGYSGEDYPQAIPELEGIEILNSSAVLVKWRPVDL 838
+VPYEI+VQA N GKGPEP+ IGYSGED P A P + N + ++W +
Sbjct: 792 PVYVPYEIRVQAENDFGKGPEPESVIGYSGEDLPSA-PRRFRVRQPNLETINLEWDHPE- 849
Query: 839 AQVKGHLRGYNVTYWREGSQRKHSKRHIHKDHVVVPANTTSVILSGLRPYSSYHLEVQAF 898
G + GY + Y K K+ + N T + P S Y + A
Sbjct: 850 -HPNGIMIGYTLKYVAFNG-TKVGKQIVEN----FSPNQTKFTVQRTDPVSRYRFTLSAR 903
Query: 899 NGRGSGPA 906
GSG A
Sbjct: 904 TQVGSGEA 911
Score = 151 bits (382), Expect = 3e-36
Identities = 208/910 (22%), Positives = 346/910 (38%), Gaps = 72/910 (7%)
Query: 136 PKWPKETVKPVEVEEGESVVLPCNPPPSAEPLRIYWMNSKILHIKQDERVTMGQNGNLYF 195
P K++ K V+ +++++ C + P + NS+ +I +D RV+M +
Sbjct: 41 PTITKQSAKDHIVDPRDNILIECEAKGNPAPSFHWTRNSRFFNIAKDPRVSMRRRSGTLV 100
Query: 196 ANVLTS----DNHSDYICHAHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSH 251
+ + + +Y C A + + +R++ + S L+P +
Sbjct: 101 IDFRSGGRPEEYEGEYQCFARNKFGTALSNR----IRLQVSKSP-------LWPKENLDP 149
Query: 252 LVALQGQPLVLECIAE-GFPTPTIKWLRPS-GPMPADRVTYQNHNKTLQLLKVGEED-DG 308
+V +G PL L+C G P+P I W+ S P+ D+ Q HN L V +D
Sbjct: 150 VVVQEGAPLTLQCNPPPGLPSPVIFWMSSSMEPITQDKRVSQGHNGDLYFSNVMLQDMQT 209
Query: 309 EYRCLAENSLGSA---RHAYYVTVEAAPYWLHKPQSHLYGPGETAR----------LDCQ 355
+Y C A ++ + + V + S +Y G + L+C
Sbjct: 210 DYSCNARFHFTHTIQQKNPFTLKVLTTRGVAERTPSFMYPQGTASSQMVLRGMDLLLECI 269
Query: 356 VQGRPQPEVTWRINGIPVEELAKDQ-KYRIQRGALILSNVQPSDTMVTQCEARNRHGLLL 414
G P P++ W G +L D+ K+ AL ++NV D+ C A N+ G +
Sbjct: 270 ASGVPTPDIAWYKKG---GDLPSDKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSIR 326
Query: 415 ANAYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERF 474
+ V P + N + G L+C+A G P P+VQW+ LQ
Sbjct: 327 HTISVRVKAAPYWLDEPKN--LILAPGEDGRLVCRANGNPKPTVQWMVNGEP--LQSAPP 382
Query: 475 FP---YANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKK 531
P A T+ RD Q + Y C +N+ + A + V D PR+ + +
Sbjct: 383 NPNREVAGDTIIFRDTQISSRAVYQCNTSNEHGYLLANAFVSVLDVPPRMLSPRNQLIRV 442
Query: 532 GSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSC 591
F S P++ W +G+ L + + E+G L I + DQG Y+C
Sbjct: 443 ILYNRTRLDCPFFGSPIPTLRWFKNGQG-SNLDGGNYHVYENGSLEIKMIRKEDQGIYTC 501
Query: 592 VASTELDVVESRAQLLVVGSPGPVPRLVLSDLH---LLTQSQVRVSWSPAEDHNAPIEKY 648
VA+ L E++ +L V P + R+ + Q + RV P+ K
Sbjct: 502 VATNILGKAENQVRL-EVKDPTRIYRMPEDQVARRGTTVQLECRVKHDPSLKLTVSWLKD 560
Query: 649 DIEFEDKEMAPEKWYSL---GKVPGNQTSTTLKLSPYVHYTFRVTAINKYGPGEPSPVSE 705
D ++ SL G +Q S T S + + + +P +
Sbjct: 561 DEPLYIGNRMKKEDDSLTIFGVAERDQGSYTCVASTELDQDLAKAYLTVLAD-QATPTNR 619
Query: 706 TVVTPEAAPEKNPVDVKGEGNETTNMVITWKPLRWMDWNAPQVQYRVQWRP-QGTRGPWQ 764
P+ P++ P D++ ++ +TW P N+P Y VQ+ Q G W
Sbjct: 620 LAALPKGRPDR-PRDLELTDLAERSVRLTWIPGDAN--NSPITDYVVQFEEDQFQPGVWH 676
Query: 765 E--QIVSDPFLVVSNTSTFVPYEIKVQAVNSQGKGPE--PQVTIGYSGEDYPQAIPELEG 820
+ + V S +V Y+ +V A+N G P SG P++ P
Sbjct: 677 DHSKYPGSVNSAVLRLSPYVNYQFRVIAINEVGSSHPSLPSERYRTSGAP-PESNPGDVK 735
Query: 821 IEILNSSAVLVKWRPVDLAQVKGHLRGYNVTYWREGSQRKHSKRHIHKDHVVVPANTTSV 880
E + + + W P++ G Y V + R ++ + + VV
Sbjct: 736 GEGTRKNNMEITWTPMNATSAFGPNLRYIVKWRRRETREAWNNVTVWGSRYVV------- 788
Query: 881 ILSGLRP-YSSYHLEVQAFNGRGSGPASEFTFS-TPEGVPGHPEALHLECQSNTSLLLRW 938
G P Y Y + VQA N G GP E + E +P P + + ++ L W
Sbjct: 789 ---GQTPVYVPYEIRVQAENDFGKGPEPESVIGYSGEDLPSAPRRFRVRQPNLETINLEW 845
Query: 939 QPPLSHNGVLTGYVLSYHPLDEGGKGQLSFNLRDPELRTHNLTDLSPHLRYRFQLQATTK 998
P NG++ GY L Y + G+ P + P RYRF L A T+
Sbjct: 846 DHPEHPNGIMIGYTLKYVAFNGTKVGKQIVENFSPNQTKFTVQRTDPVSRYRFTLSARTQ 905
Query: 999 EGPGEAIVRE 1008
G GEA+ E
Sbjct: 906 VGSGEAVTEE 915
Score = 144 bits (362), Expect = 7e-34
Identities = 77/142 (54%), Positives = 98/142 (69%), Gaps = 5/142 (3%)
Query: 1115 AGFATEGWFIGFVSAIILLLLVLLILCFIKRSKGGKYSVKDKEDTQVDSEARPMKDETFG 1174
A AT+GWFIG + AI LL+L+LLI+CFIKRS+GGKY V++K+D + E +D +F
Sbjct: 1103 ADIATQGWFIGLMCAIALLVLILLIVCFIKRSRGGKYPVREKKDVPLGPEDPKEEDGSF- 1161
Query: 1175 EYRSLESDNEEKAFGSSQPSLNGDIKPLGSDDSLADYGGSVDVQFNEDGSFIGQYSGKKE 1234
+Y SD + K SQ SL+G IK SDDSL DYG + QFNEDGSFIGQY+ KK+
Sbjct: 1162 DY----SDEDNKPLQGSQTSLDGTIKQQESDDSLVDYGEGGEGQFNEDGSFIGQYTVKKD 1217
Query: 1235 KEAAGGNDSSGATSPINPAVAL 1256
KE GN+SS ATSP+N +L
Sbjct: 1218 KEETEGNESSEATSPVNAIYSL 1239
Score = 38.1 bits (87), Expect = 0.053
Identities = 33/136 (24%), Positives = 54/136 (39%), Gaps = 6/136 (4%)
Query: 914 PEGVPGHPEALHLECQSNTSLLLRWQPPLSHNGVLTGYVLSYHPLDEGGKGQLSFNLRDP 973
P+G P P L L + S+ L W P ++N +T YV+ + D+ G + + P
Sbjct: 624 PKGRPDRPRDLELTDLAERSVRLTWIPGDANNSPITDYVVQFEE-DQFQPGVWHDHSKYP 682
Query: 974 ELRTHNLTDLSPHLRYRFQLQATTKEGPGEAIVREGGTMALSGISDFGNISATAGE---- 1029
+ LSP++ Y+F++ A + G + SG N GE
Sbjct: 683 GSVNSAVLRLSPYVNYQFRVIAINEVGSSHPSL-PSERYRTSGAPPESNPGDVKGEGTRK 741
Query: 1030 NYSVVSWVPKEGQCNF 1045
N ++W P F
Sbjct: 742 NNMEITWTPMNATSAF 757
>gi|237858682 neurofascin isoform 6 precursor [Homo sapiens]
Length = 613
Score = 452 bits (1162), Expect = e-126
Identities = 232/600 (38%), Positives = 345/600 (57%), Gaps = 15/600 (2%)
Query: 17 CLL-----IQIPEEYEGHHVMEPPVITEQSPRRLVVFPTDDISLKCEASGKPEVQFRWTR 71
CLL I+IP + + +PP IT+QS + +V P D+I ++CEA G P F WTR
Sbjct: 17 CLLSLGGAIEIPMD-----LTQPPTITKQSAKDHIVDPRDNILIECEAKGNPAPSFHWTR 71
Query: 72 DGVHFKPKEELGVTVYQSPHSGSFTITGNNSNFAQRFQGIYRCFASNKLGTAMSHEIRLM 131
+ F ++ V++ + SG+ I + + ++G Y+CFA NK GTA+S+ IRL
Sbjct: 72 NSRFFNIAKDPRVSMRR--RSGTLVIDFRSGGRPEEYEGEYQCFARNKFGTALSNRIRLQ 129
Query: 132 AEGAPKWPKETVKPVEVEEGESVVLPCNPPPSAEPLRIYWMNSKILHIKQDERVTMGQNG 191
+P WPKE + PV V+EG + L CNPPP I+WM+S + I QD+RV+ G NG
Sbjct: 130 VSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWMSSSMEPITQDKRVSQGHNG 189
Query: 192 NLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSH 251
+LYF+NV+ D +DY C+A F T TI QK P L+V T + +R P ++P ++S
Sbjct: 190 DLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVLTTRGVAERTPSFMYPQGTASS 249
Query: 252 LVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYR 311
+ L+G L+LECIA G PTP I W + G +P+D+ ++N NK L++ V EED GEY
Sbjct: 250 QMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPSDKAKFENFNKALRITNVSEEDSGEYF 309
Query: 312 CLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGI 371
CLA N +GS RH V V+AAPYWL +P++ + PGE RL C+ G P+P V W +NG
Sbjct: 310 CLASNKMGSIRHTISVRVKAAPYWLDEPKNLILAPGEDGRLVCRANGNPKPTVQWMVNGE 369
Query: 372 PVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTA 431
P++ + + +I + Q S V QC N HG LLANA++ V+ +P ++L+
Sbjct: 370 PLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCNTSNEHGYLLANAFVSVLDVPPRMLSP 429
Query: 432 DNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQAND 491
NQ + + L C FG+P+P+++W + L + Y NG+L I+ ++ D
Sbjct: 430 RNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGSLEIKMIRKED 489
Query: 492 TGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSI 551
G Y C+A N L+VKD T+I + P + ++G+ V C+ DPSL+ ++
Sbjct: 490 QGIYTCVATNILGKAENQVRLEVKDPTRIYRMPEDQVARRGTTVQLECRVKHDPSLKLTV 549
Query: 552 TWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGS 611
+W D L +G+ K ED L I + DQG+Y+CVASTELD ++A L V+G+
Sbjct: 550 SWLKDDEPLY-IGNRMKK--EDDSLTIFGVAERDQGSYTCVASTELDQDLAKAYLTVLGN 606
Score = 67.0 bits (162), Expect = 1e-10
Identities = 72/295 (24%), Positives = 119/295 (40%), Gaps = 28/295 (9%)
Query: 340 QSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQR--GALIL---SNV 394
+ H+ P + ++C+ +G P P W N +AKD + ++R G L++ S
Sbjct: 43 KDHIVDPRDNILIECEAKGNPAPSFHWTRNS-RFFNIAKDPRVSMRRRSGTLVIDFRSGG 101
Query: 395 QPSDTMVT-QCEARNRHGLLLANAYIYVVQLPAKILTADNQTYMAVQ-GSTAYLLCKAF- 451
+P + QC ARN+ G L+N V + + +N + VQ G+ L C
Sbjct: 102 RPEEYEGEYQCFARNKFGTALSNRIRLQVS-KSPLWPKENLDPVVVQEGAPLTLQCNPPP 160
Query: 452 GAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQAND-------TGRYFCLAANDQN 504
G P P + W+ + QD+R NG L ++ D R+ Q
Sbjct: 161 GLPSPVIFWMSSSMEPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQK 220
Query: 505 N---VTIMANLKVKDATQITQGPRSTIEK----KGSRVTFTCQASFDPSLQPSITWRGDG 557
N + ++ V + T P+ T +G + C AS P+ P I W G
Sbjct: 221 NPFTLKVLTTRGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPT--PDIAWYKKG 278
Query: 558 RDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSP 612
DL D K+ + L I ++ D G Y C+AS ++ + + V +P
Sbjct: 279 GDLPS--DKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAP 331
>gi|237858680 neurofascin isoform 5 precursor [Homo sapiens]
Length = 619
Score = 452 bits (1162), Expect = e-126
Identities = 232/601 (38%), Positives = 346/601 (57%), Gaps = 11/601 (1%)
Query: 17 CLL-----IQIPEEYE-GHHVMEPPVITEQSPRRLVVFPTDDISLKCEASGKPEVQFRWT 70
CLL I+IP + + + +PP IT+QS + +V P D+I ++CEA G P F WT
Sbjct: 17 CLLSLGGAIEIPMDPSIQNELTQPPTITKQSAKDHIVDPRDNILIECEAKGNPAPSFHWT 76
Query: 71 RDGVHFKPKEELGVTVYQSPHSGSFTITGNNSNFAQRFQGIYRCFASNKLGTAMSHEIRL 130
R+ F ++ V++ + SG+ I + + ++G Y+CFA NK GTA+S+ IRL
Sbjct: 77 RNSRFFNIAKDPRVSMRR--RSGTLVIDFRSGGRPEEYEGEYQCFARNKFGTALSNRIRL 134
Query: 131 MAEGAPKWPKETVKPVEVEEGESVVLPCNPPPSAEPLRIYWMNSKILHIKQDERVTMGQN 190
+P WPKE + PV V+EG + L CNPPP I+WM+S + I QD+RV+ G N
Sbjct: 135 QVSKSPLWPKENLDPVVVQEGAPLTLQCNPPPGLPSPVIFWMSSSMEPITQDKRVSQGHN 194
Query: 191 GNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSS 250
G+LYF+NV+ D +DY C+A F T TI QK P L+V T + +R P ++P ++S
Sbjct: 195 GDLYFSNVMLQDMQTDYSCNARFHFTHTIQQKNPFTLKVLTTRGVAERTPSFMYPQGTAS 254
Query: 251 HLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEY 310
+ L+G L+LECIA G PTP I W + G +P+D+ ++N NK L++ V EED GEY
Sbjct: 255 SQMVLRGMDLLLECIASGVPTPDIAWYKKGGDLPSDKAKFENFNKALRITNVSEEDSGEY 314
Query: 311 RCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRING 370
CLA N +GS RH V V+AAPYWL +P++ + PGE RL C+ G P+P V W +NG
Sbjct: 315 FCLASNKMGSIRHTISVRVKAAPYWLDEPKNLILAPGEDGRLVCRANGNPKPTVQWMVNG 374
Query: 371 IPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILT 430
P++ + + +I + Q S V QC N HG LLANA++ V+ +P ++L+
Sbjct: 375 EPLQSAPPNPNREVAGDTIIFRDTQISSRAVYQCNTSNEHGYLLANAFVSVLDVPPRMLS 434
Query: 431 ADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQAN 490
NQ + + L C FG+P+P+++W + L + Y NG+L I+ ++
Sbjct: 435 PRNQLIRVILYNRTRLDCPFFGSPIPTLRWFKNGQGSNLDGGNYHVYENGSLEIKMIRKE 494
Query: 491 DTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPS 550
D G Y C+A N L+VKD T+I + P + ++G+ V C+ DPSL+ +
Sbjct: 495 DQGIYTCVATNILGKAENQVRLEVKDPTRIYRMPEDQVARRGTTVQLECRVKHDPSLKLT 554
Query: 551 ITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVG 610
++W D L +G+ K ED L I + DQG+Y+CVASTELD ++A L V+G
Sbjct: 555 VSWLKDDEPLY-IGNRMKK--EDDSLTIFGVAERDQGSYTCVASTELDQDLAKAYLTVLG 611
Query: 611 S 611
+
Sbjct: 612 N 612
Score = 67.0 bits (162), Expect = 1e-10
Identities = 72/295 (24%), Positives = 119/295 (40%), Gaps = 28/295 (9%)
Query: 340 QSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQR--GALIL---SNV 394
+ H+ P + ++C+ +G P P W N +AKD + ++R G L++ S
Sbjct: 49 KDHIVDPRDNILIECEAKGNPAPSFHWTRNS-RFFNIAKDPRVSMRRRSGTLVIDFRSGG 107
Query: 395 QPSDTMVT-QCEARNRHGLLLANAYIYVVQLPAKILTADNQTYMAVQ-GSTAYLLCKAF- 451
+P + QC ARN+ G L+N V + + +N + VQ G+ L C
Sbjct: 108 RPEEYEGEYQCFARNKFGTALSNRIRLQVS-KSPLWPKENLDPVVVQEGAPLTLQCNPPP 166
Query: 452 GAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQAND-------TGRYFCLAANDQN 504
G P P + W+ + QD+R NG L ++ D R+ Q
Sbjct: 167 GLPSPVIFWMSSSMEPITQDKRVSQGHNGDLYFSNVMLQDMQTDYSCNARFHFTHTIQQK 226
Query: 505 N---VTIMANLKVKDATQITQGPRSTIEK----KGSRVTFTCQASFDPSLQPSITWRGDG 557
N + ++ V + T P+ T +G + C AS P+ P I W G
Sbjct: 227 NPFTLKVLTTRGVAERTPSFMYPQGTASSQMVLRGMDLLLECIASGVPT--PDIAWYKKG 284
Query: 558 RDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSP 612
DL D K+ + L I ++ D G Y C+AS ++ + + V +P
Sbjct: 285 GDLPS--DKAKFENFNKALRITNVSEEDSGEYFCLASNKMGSIRHTISVRVKAAP 337
>gi|75709184 contactin 3 [Homo sapiens]
Length = 1028
Score = 409 bits (1050), Expect = e-113
Identities = 296/1004 (29%), Positives = 463/1004 (46%), Gaps = 68/1004 (6%)
Query: 28 GHHVMEPPVITEQSPRRLVVFPTDD--ISLKCEASGKPEVQFRWTRDGVHFKPKEELGVT 85
G +++ PV ++ + ++D I+L CEA G P +RW +G ++ +
Sbjct: 19 GELLLQGPVFIKEPSNSIFPVGSEDKKITLHCEARGNPSPHYRWQLNGSDI----DMSME 74
Query: 86 VYQSPHSGSFTITGNNSNFAQRFQGIYRCFASNKLGTAMSHEIRLMAEGAPKWPKETVKP 145
+ G+ + N N+ G Y+CFA+N LGT +S E +L + +
Sbjct: 75 HRYKLNGGNLVVINPNRNWDT---GTYQCFATNSLGTIVSREAKLQFAYLENFKTKMRST 131
Query: 146 VEVEEGESVVLPCNPPPSAEPLRIYWM-NSKILHIKQDERVTMGQN-GNLYFANVLTSDN 203
V V EG+ VVL C PPP + L W+ N +++D R + Q G+LY + V SD
Sbjct: 132 VSVREGQGVVLLCGPPPHSGELSYAWIFNEYPSFVEEDSRRFVSQETGHLYISKVEPSDV 191
Query: 204 HSDYICHAHFPGTRTIIQKEPIDLRVKATNSMIDRKPRL--LFPTNSSSHLVALQGQPLV 261
+Y C T + P L +++ M + +P++ FP L A +G +
Sbjct: 192 -GNYTCVVTSMVTNARVLGSPTPLVLRSDGVMGEYEPKIEVQFPET----LPAAKGSTVK 246
Query: 262 LECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSA 321
LEC A G P P I W R G + ++ + + L++ +ED G Y C+AENS G
Sbjct: 247 LECFALGNPIPQINWRRSDGLPFSSKIKLRKFSGVLEIPNFQQEDAGSYECIAENSRGKN 306
Query: 322 RHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQK 381
+T A P+W+ + ++ +C+ G+P+P W NG L +++
Sbjct: 307 VARGRLTYYAKPHWVQLIKDVEIAVEDSLYWECRASGKPKPSYRWLKNGAA---LVLEER 363
Query: 382 YRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQTYMAVQ- 440
+I+ GAL +SN+ +D+ + QC A N+HGL+ ++A + VV + + VQ
Sbjct: 364 TQIENGALTISNLSVTDSGMFQCIAENKHGLVYSSAELKVVASAPDFSKNPMKKLVQVQV 423
Query: 441 GSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAA 500
GS L CK +P W D +V + ER +G L I ++ D G Y C+A
Sbjct: 424 GSLVSLDCKPRASPRALSSWKKGD-VSVQEHERISLLNDGGLKIANVTKADAGTYTCMAE 482
Query: 501 NDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITW------- 553
N +L V + T+IT P + G V CQ DP L TW
Sbjct: 483 NQFGKANGTTHLVVTEPTRITLAPSNMDVSVGESVILPCQVQHDPLLDIIFTWYFNGALA 542
Query: 554 --RGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGS 611
+ DG +++G S G L+I ++ G Y C+ T +D V S A L+V GS
Sbjct: 543 DFKKDGSHFEKVGGSSS-----GDLMIRNIQLKHSGKYVCMVQTGVDSVSSAADLIVRGS 597
Query: 612 PGPVPRLVLSDLHLLTQSQVRVSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPG- 670
PGP + + ++ T + ++SW +D+++P+ Y I+ W ++ VP
Sbjct: 598 PGPPENVKVDEI---TDTTAQLSWKEGKDNHSPVISYSIQARTPFSVG--WQTVTTVPEV 652
Query: 671 ----NQTSTTLKLSPYVHYTFRVTAINKYGPGEPSPVSETVVTPEAAPEKNPVDVKGEGN 726
T+T ++L+P+V Y FRV A NK G GEPS SE V T EA PE P +V G G
Sbjct: 653 IDGKTHTATVVELNPWVEYEFRVVASNKIGGGEPSLPSEKVRTEEAVPEVPPSEVNGGGG 712
Query: 727 ETTNMVITWKPLRWMDWNAPQVQYRVQWRPQGTRGPWQEQIVSD---PFLVVSNTS--TF 781
+ +VITW P+ N Y V +RP G W + +V+ P V N S +
Sbjct: 713 SRSELVITWDPVPEELQNGEGFGYVVAFRPLGVT-TWIQTVVTSPDTPRYVFRNESIVPY 771
Query: 782 VPYEIKVQAVNSQGKGPEPQVTIGYSGEDYPQAIPELEGIEILNSSAVLVKWRPVDLAQV 841
PYE+KV N++G+GP VT +S E+ P P L+SS + V W +
Sbjct: 772 SPYEVKVGVYNNKGEGPFSPVTTVFSAEEEPTVAPSQVSANSLSSSEIEVSWNTIPWKLS 831
Query: 842 KGHLRGYNVTYWREGSQRKHSKRHIHKDHVVVPANTTSVILSGLRPYSSYHLEVQAFNGR 901
GHL GY V YW G + + S + + V N TS L GL+ +Y+ V+A+N
Sbjct: 832 NGHLLGYEVRYWNGGGKEESSSK------MKVAGNETSARLRGLKSNLAYYTAVRAYNSA 885
Query: 902 GSGP-ASEFTFSTPEGVPGHPEALHLECQSNTSLLLRWQ--PPLSHNGVLTGYVLSYHPL 958
G+GP ++ +T + P P + ++T +LL W+ + + +TGY + Y
Sbjct: 886 GAGPFSATVNVTTKKTPPSQPPGNVVWNATDTKVLLNWEQVKAMENESEVTGYKVFYRTS 945
Query: 959 DEGGKGQLSFNLRDPELRTHNLTDLSPHLRYRFQLQATTKEGPG 1002
+ L+ N EL D Y +++ATT G G
Sbjct: 946 SQNNVQVLNTNKTSAELVLPIKED------YIIEVKATTDGGDG 983
Score = 38.9 bits (89), Expect = 0.031
Identities = 42/187 (22%), Positives = 84/187 (44%), Gaps = 20/187 (10%)
Query: 916 GVPGHPEALHLECQSNTSLLLRWQPPL-SHNGVLTGYVLSYHPLDEGGKGQLSF-NLRDP 973
G PG PE + ++ ++T+ L W+ +H+ V++ + + P G + + + D
Sbjct: 596 GSPGPPENVKVDEITDTTAQLSWKEGKDNHSPVISYSIQARTPFSVGWQTVTTVPEVIDG 655
Query: 974 ELRTHNLTDLSPHLRYRFQLQATTKEGPGEAIVREGGTMALSGISDFGNISATAG---EN 1030
+ T + +L+P + Y F++ A+ K G GE + + + G +
Sbjct: 656 KTHTATVVELNPWVEYEFRVVASNKIGGGEPSLPSEKVRTEEAVPEVPPSEVNGGGGSRS 715
Query: 1031 YSVVSW--VPKEGQC--NFRFHILFKALGEEKGGASL-----SPQYVSYNQSSYTQWDLQ 1081
V++W VP+E Q F + + F+ LG ++ +P+YV N+S +
Sbjct: 716 ELVITWDPVPEELQNGEGFGYVVAFRPLGVTTWIQTVVTSPDTPRYVFRNES------IV 769
Query: 1082 PDTDYEI 1088
P + YE+
Sbjct: 770 PYSPYEV 776
>gi|7657359 contactin 5 isoform long [Homo sapiens]
Length = 1100
Score = 404 bits (1037), Expect = e-112
Identities = 280/943 (29%), Positives = 451/943 (47%), Gaps = 70/943 (7%)
Query: 46 VVFPTDD----ISLKCEASGKPEVQFRWTRDGVHFKPKEELGVTVYQSPHSGSFTITGNN 101
++FPTD ++L CE G P +RW R+G + + ++ G+F I+ +
Sbjct: 108 IIFPTDSDEKKVALNCEVRGNPVPSYRWLRNGTEIDLESDYRYSLID----GTFIISNPS 163
Query: 102 SNFAQRFQGIYRCFASNKLGTAMSHEIRLMAEGAPKWPKETVKPVEVEEGESVVLPCNPP 161
+ G Y+C A+N +G+ +S E L + T V V EG+ VVL C+PP
Sbjct: 164 E---AKDSGHYQCLATNTVGSILSREATLQFAYLGNFSGRTRSAVSVREGQGVVLMCSPP 220
Query: 162 PSAEPLRIYWM-NSKILHIKQDERVTMGQN-GNLYFANVLTSDNHSDYICHAHFPGTRTI 219
P + + W+ N + +D R + Q GNLY + V TSD S YIC T
Sbjct: 221 PHSPEIIYSWVFNEFPSFVAEDSRRFISQETGNLYISKVQTSDVGS-YICLVKNTVTNAR 279
Query: 220 IQKEPIDLRVKATNSMIDRKPRLL--FPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWL 277
+ P L ++ M + +P++ FP + A +G + +EC A G P PTI W+
Sbjct: 280 VLSPPTPLTLRNDGVMGEYEPKIEVHFPFT----VTAAKGTTVKMECFALGNPVPTITWM 335
Query: 278 RPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLH 337
+ +G +P+ + + L++ V +D G Y C AENS G + V P+W+
Sbjct: 336 KVNGYIPS-KARLRKSQAVLEIPNVQLDDAGIYECRAENSRGKNSFRGQLQVYTYPHWVE 394
Query: 338 KPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPS 397
K G R +C+ G+P+P W NG+P L+ + + G L++ NV S
Sbjct: 395 KLNDTQLDSGSPLRWECKATGKPRPTYRWLKNGVP---LSPQSRVEMVNGVLMIHNVNQS 451
Query: 398 DTMVTQCEARNRHGLLLANAYIYVV-QLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVP 456
D + QC A N++G + A+A + ++ P L +T + + + CK G+P P
Sbjct: 452 DAGMYQCLAENKYGAIYASAELKILASAPTFALNQLKKTIIVTKDQEVVIECKPQGSPKP 511
Query: 457 SVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 516
++ W D V +++R +G+L I + +D G+Y C N + I+A+L VK+
Sbjct: 512 TISWKKGD-RAVRENKRIAILPDGSLRILNASKSDEGKYVCRGENVFGSAEIIASLSVKE 570
Query: 517 ATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITW--RGDGRDLQELG---DSDKYFI 571
T+I P+ T G + C+A D SL + W +G D +E G +S +
Sbjct: 571 PTRIELTPKRTELTVGESIVLNCKAIHDASLDVTFYWTLKGQPIDFEEEGGHFESIRAQA 630
Query: 572 EDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQV 631
L+I ++ G Y C T D V A+LLV G PGP +++ ++ T+S
Sbjct: 631 SSADLMIRNILLMHAGRYGCRVQTTADSVSDEAELLVRGPPGPPGIVIVEEI---TESTA 687
Query: 632 RVSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVP-----GNQTSTTLKLSPYVHYT 686
+SWSPA D+++PI Y+++ W ++ VP +++ + L+P+V Y
Sbjct: 688 TLSWSPAADNHSPISSYNLQARSPFSLG--WQTVKTVPEIITGDMESAMAVDLNPWVEYE 745
Query: 687 FRVTAINKYGPGEPSPVSETVVTPEAAPEKNPVDVKGEGNETTNMVITWKPLRWMDWNAP 746
FRV A N G G+PS S + T EA P+ P +V G +VI W+P+ N
Sbjct: 746 FRVVATNPIGTGDPSTPSRMIRTNEAVPKTAPTNVSGRSGRRHELVIAWEPVSEEFQNGE 805
Query: 747 QVQYRVQWRPQGTRGPWQEQIVSDPFLVVSNTSTFV----------PYEIKVQAVNSQGK 796
Y V +RP GTRG W+E++V+ S S F+ P+E+KV N++G
Sbjct: 806 GFGYIVAFRPNGTRG-WKEKMVTS-----SEASKFIYRDESVPPLTPFEVKVGVYNNKGD 859
Query: 797 GPEPQVTIGYSGEDYPQAIPELEGIEILNSSAVLVKWRPVDLAQVKGHLRGYNVTYWREG 856
GP Q+ + S E P A P ++ S +LV W+ + + G +G+ V YW++
Sbjct: 860 GPFSQIVVICSAEGEPSAAPTDVKATSVSVSEILVAWK--HIKESLGRPQGFEVGYWKDM 917
Query: 857 SQRKHSKRHIHKDHVVVPANTTSVILSGLRPYSSYHLEVQAFNGRGSG-PASEFTFSTPE 915
Q + + V N + VIL+GL + YH V+A+NG G G P+SE + +T +
Sbjct: 918 EQEDTA------ETVKTRGNESFVILTGLEGNTLYHFTVRAYNGAGYGPPSSEVSATTKK 971
Query: 916 GVPGH-PEALHLECQSNTSLLLRWQP--PLSHNGVLTGYVLSY 955
P P L E Q + + L W+P PL++ + GY + Y
Sbjct: 972 SPPSQAPSNLRWE-QQGSQVSLGWEPVIPLANESEVVGYKVFY 1013
Score = 99.0 bits (245), Expect = 3e-20
Identities = 160/698 (22%), Positives = 265/698 (37%), Gaps = 91/698 (13%)
Query: 257 GQPLVLECIAEGFPTPTIKWLRPSGPM-PADRVTYQNHNKTLQLLKVGEEDDGEYRCLAE 315
G PL EC A G P PT +WL+ P+ P RV + N L + V + D G Y+CLAE
Sbjct: 404 GSPLRWECKATGKPRPTYRWLKNGVPLSPQSRV--EMVNGVLMIHNVNQSDAGMYQCLAE 461
Query: 316 NSLGS--ARHAYYVTVEAAPYWLHK-PQSHLYGPGETARLDCQVQGRPQPEVTWRINGIP 372
N G+ A + A + L++ ++ + + ++C+ QG P+P ++W+
Sbjct: 462 NKYGAIYASAELKILASAPTFALNQLKKTIIVTKDQEVVIECKPQGSPKPTISWKKGDRA 521
Query: 373 VEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTAD 432
V E + + G+L + N SD C N G A + V + P +I
Sbjct: 522 VRE--NKRIAILPDGSLRILNASKSDEGKYVCRGENVFGSAEIIASLSVKE-PTRIELTP 578
Query: 433 NQTYMAVQGSTAYLLCKAF-GAPVPSVQWLDEDGTTVLQDERFFPY-------ANGTLGI 484
+T + V G + L CKA A + + G + +E + ++ L I
Sbjct: 579 KRTELTV-GESIVLNCKAIHDASLDVTFYWTLKGQPIDFEEEGGHFESIRAQASSADLMI 637
Query: 485 RDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTI---EKKGSRVTFTCQA 541
R++ GRY C ++V+ A L V+ GP + E S T +
Sbjct: 638 RNILLMHAGRYGCRVQTTADSVSDEAELLVRGPP----GPPGIVIVEEITESTATLSWSP 693
Query: 542 SFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVE 601
+ D + P ++ R LG + + ++ ++ + + + E VV
Sbjct: 694 AAD-NHSPISSYNLQARSPFSLGWQTVKTVPE--IITGDMESAMAVDLNPWVEYEFRVVA 750
Query: 602 SRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAEDHNAPI--EKYDIEFEDKE--- 656
+ + G P R++ ++ + + VS H I E EF++ E
Sbjct: 751 TNP--IGTGDPSTPSRMIRTNEAVPKTAPTNVSGRSGRRHELVIAWEPVSEEFQNGEGFG 808
Query: 657 ----MAPE--KWYSLGKVPGNQTSTTL----KLSPYVHYTFRVTAINKYGPGEPSPVSET 706
P + + V ++ S + + P + +V N G G P S+
Sbjct: 809 YIVAFRPNGTRGWKEKMVTSSEASKFIYRDESVPPLTPFEVKVGVYNNKGDG---PFSQI 865
Query: 707 VV--TPEAAPEKNPVDVKGEGNETTNMVITWKPLRWMDWNAPQVQYRVQWRPQGTR-GPW 763
VV + E P P DVK + +++ WK ++ RPQG G W
Sbjct: 866 VVICSAEGEPSAAPTDVKATSVSVSEILVAWKHIK-----------ESLGRPQGFEVGYW 914
Query: 764 QEQIVSDP-----------FLVVSNTSTFVPYEIKVQAVNSQGKGPEPQVTIGYSGEDYP 812
++ D F++++ Y V+A N G GP + + P
Sbjct: 915 KDMEQEDTAETVKTRGNESFVILTGLEGNTLYHFTVRAYNGAGYGPPSSEVSATTKKSPP 974
Query: 813 QAIPELEGIEILNSSAVLVKWRPVDLAQVKGHLRGYNVTYWREGSQRKHSKRHI---HKD 869
P E S V + W PV + + GY V Y +EG HS + K
Sbjct: 975 SQAPSNLRWE-QQGSQVSLGWEPVIPLANESEVVGYKVFYRQEG----HSNSQVIETQKL 1029
Query: 870 HVVVPANTTSVILSGLRPYSSYHLEVQAFNGRGSGPAS 907
VVP V Y +EV+A++ G G AS
Sbjct: 1030 QAVVPLPDAGV----------YIIEVRAYSEGGDGTAS 1057
Score = 36.6 bits (83), Expect = 0.16
Identities = 31/139 (22%), Positives = 55/139 (39%), Gaps = 12/139 (8%)
Query: 34 PPVITEQSPRRLVVFPTDDISLKCEASGKPEVQFRWTRDGVHFKPKEELGVTVYQSPHSG 93
P Q + ++V ++ ++C+ G P+ W + + + + + G
Sbjct: 480 PTFALNQLKKTIIVTKDQEVVIECKPQGSPKPTISWKKGDRAVRENKRIAIL-----PDG 534
Query: 94 SFTITGNNSNFAQRFQGIYRCFASNKLGTAMSHEIRLMAEGAPKWPKETVKPVEVEEGES 153
S I N ++ +G Y C N G+A I ++ P + T K E+ GES
Sbjct: 535 SLRIL----NASKSDEGKYVCRGENVFGSA--EIIASLSVKEPTRIELTPKRTELTVGES 588
Query: 154 VVLPCNPPPSAE-PLRIYW 171
+VL C A + YW
Sbjct: 589 IVLNCKAIHDASLDVTFYW 607
Score = 33.5 bits (75), Expect = 1.3
Identities = 31/135 (22%), Positives = 60/135 (44%), Gaps = 19/135 (14%)
Query: 916 GVPGHPEALHLECQSNTSLLLRWQPPLSHNGVLTGYVLSYH-PLDEGGKGQLSFNLRDPE 974
G PG P + +E + ++ L W P ++ ++ Y L P G + + PE
Sbjct: 669 GPPGPPGIVIVEEITESTATLSWSPAADNHSPISSYNLQARSPFSLGWQTVKTV----PE 724
Query: 975 LRTHNL-----TDLSPHLRYRFQLQATTKEGPGE-----AIVREGGTMALSGISDFGNIS 1024
+ T ++ DL+P + Y F++ AT G G+ ++R + + + N+S
Sbjct: 725 IITGDMESAMAVDLNPWVEYEFRVVATNPIGTGDPSTPSRMIRTNEAVPKTAPT---NVS 781
Query: 1025 ATAGENYS-VVSWVP 1038
+G + V++W P
Sbjct: 782 GRSGRRHELVIAWEP 796
>gi|28373129 contactin 5 isoform short [Homo sapiens]
Length = 1026
Score = 404 bits (1037), Expect = e-112
Identities = 280/943 (29%), Positives = 451/943 (47%), Gaps = 70/943 (7%)
Query: 46 VVFPTDD----ISLKCEASGKPEVQFRWTRDGVHFKPKEELGVTVYQSPHSGSFTITGNN 101
++FPTD ++L CE G P +RW R+G + + ++ G+F I+ +
Sbjct: 34 IIFPTDSDEKKVALNCEVRGNPVPSYRWLRNGTEIDLESDYRYSLID----GTFIISNPS 89
Query: 102 SNFAQRFQGIYRCFASNKLGTAMSHEIRLMAEGAPKWPKETVKPVEVEEGESVVLPCNPP 161
+ G Y+C A+N +G+ +S E L + T V V EG+ VVL C+PP
Sbjct: 90 E---AKDSGHYQCLATNTVGSILSREATLQFAYLGNFSGRTRSAVSVREGQGVVLMCSPP 146
Query: 162 PSAEPLRIYWM-NSKILHIKQDERVTMGQN-GNLYFANVLTSDNHSDYICHAHFPGTRTI 219
P + + W+ N + +D R + Q GNLY + V TSD S YIC T
Sbjct: 147 PHSPEIIYSWVFNEFPSFVAEDSRRFISQETGNLYISKVQTSDVGS-YICLVKNTVTNAR 205
Query: 220 IQKEPIDLRVKATNSMIDRKPRLL--FPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWL 277
+ P L ++ M + +P++ FP + A +G + +EC A G P PTI W+
Sbjct: 206 VLSPPTPLTLRNDGVMGEYEPKIEVHFPFT----VTAAKGTTVKMECFALGNPVPTITWM 261
Query: 278 RPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLH 337
+ +G +P+ + + L++ V +D G Y C AENS G + V P+W+
Sbjct: 262 KVNGYIPS-KARLRKSQAVLEIPNVQLDDAGIYECRAENSRGKNSFRGQLQVYTYPHWVE 320
Query: 338 KPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPS 397
K G R +C+ G+P+P W NG+P L+ + + G L++ NV S
Sbjct: 321 KLNDTQLDSGSPLRWECKATGKPRPTYRWLKNGVP---LSPQSRVEMVNGVLMIHNVNQS 377
Query: 398 DTMVTQCEARNRHGLLLANAYIYVV-QLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVP 456
D + QC A N++G + A+A + ++ P L +T + + + CK G+P P
Sbjct: 378 DAGMYQCLAENKYGAIYASAELKILASAPTFALNQLKKTIIVTKDQEVVIECKPQGSPKP 437
Query: 457 SVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKD 516
++ W D V +++R +G+L I + +D G+Y C N + I+A+L VK+
Sbjct: 438 TISWKKGD-RAVRENKRIAILPDGSLRILNASKSDEGKYVCRGENVFGSAEIIASLSVKE 496
Query: 517 ATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITW--RGDGRDLQELG---DSDKYFI 571
T+I P+ T G + C+A D SL + W +G D +E G +S +
Sbjct: 497 PTRIELTPKRTELTVGESIVLNCKAIHDASLDVTFYWTLKGQPIDFEEEGGHFESIRAQA 556
Query: 572 EDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQV 631
L+I ++ G Y C T D V A+LLV G PGP +++ ++ T+S
Sbjct: 557 SSADLMIRNILLMHAGRYGCRVQTTADSVSDEAELLVRGPPGPPGIVIVEEI---TESTA 613
Query: 632 RVSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVP-----GNQTSTTLKLSPYVHYT 686
+SWSPA D+++PI Y+++ W ++ VP +++ + L+P+V Y
Sbjct: 614 TLSWSPAADNHSPISSYNLQARSPFSLG--WQTVKTVPEIITGDMESAMAVDLNPWVEYE 671
Query: 687 FRVTAINKYGPGEPSPVSETVVTPEAAPEKNPVDVKGEGNETTNMVITWKPLRWMDWNAP 746
FRV A N G G+PS S + T EA P+ P +V G +VI W+P+ N
Sbjct: 672 FRVVATNPIGTGDPSTPSRMIRTNEAVPKTAPTNVSGRSGRRHELVIAWEPVSEEFQNGE 731
Query: 747 QVQYRVQWRPQGTRGPWQEQIVSDPFLVVSNTSTFV----------PYEIKVQAVNSQGK 796
Y V +RP GTRG W+E++V+ S S F+ P+E+KV N++G
Sbjct: 732 GFGYIVAFRPNGTRG-WKEKMVTS-----SEASKFIYRDESVPPLTPFEVKVGVYNNKGD 785
Query: 797 GPEPQVTIGYSGEDYPQAIPELEGIEILNSSAVLVKWRPVDLAQVKGHLRGYNVTYWREG 856
GP Q+ + S E P A P ++ S +LV W+ + + G +G+ V YW++
Sbjct: 786 GPFSQIVVICSAEGEPSAAPTDVKATSVSVSEILVAWK--HIKESLGRPQGFEVGYWKDM 843
Query: 857 SQRKHSKRHIHKDHVVVPANTTSVILSGLRPYSSYHLEVQAFNGRGSG-PASEFTFSTPE 915
Q + + V N + VIL+GL + YH V+A+NG G G P+SE + +T +
Sbjct: 844 EQEDTA------ETVKTRGNESFVILTGLEGNTLYHFTVRAYNGAGYGPPSSEVSATTKK 897
Query: 916 GVPGH-PEALHLECQSNTSLLLRWQP--PLSHNGVLTGYVLSY 955
P P L E Q + + L W+P PL++ + GY + Y
Sbjct: 898 SPPSQAPSNLRWE-QQGSQVSLGWEPVIPLANESEVVGYKVFY 939
Score = 99.0 bits (245), Expect = 3e-20
Identities = 160/698 (22%), Positives = 265/698 (37%), Gaps = 91/698 (13%)
Query: 257 GQPLVLECIAEGFPTPTIKWLRPSGPM-PADRVTYQNHNKTLQLLKVGEEDDGEYRCLAE 315
G PL EC A G P PT +WL+ P+ P RV + N L + V + D G Y+CLAE
Sbjct: 330 GSPLRWECKATGKPRPTYRWLKNGVPLSPQSRV--EMVNGVLMIHNVNQSDAGMYQCLAE 387
Query: 316 NSLGS--ARHAYYVTVEAAPYWLHK-PQSHLYGPGETARLDCQVQGRPQPEVTWRINGIP 372
N G+ A + A + L++ ++ + + ++C+ QG P+P ++W+
Sbjct: 388 NKYGAIYASAELKILASAPTFALNQLKKTIIVTKDQEVVIECKPQGSPKPTISWKKGDRA 447
Query: 373 VEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTAD 432
V E + + G+L + N SD C N G A + V + P +I
Sbjct: 448 VRE--NKRIAILPDGSLRILNASKSDEGKYVCRGENVFGSAEIIASLSVKE-PTRIELTP 504
Query: 433 NQTYMAVQGSTAYLLCKAF-GAPVPSVQWLDEDGTTVLQDERFFPY-------ANGTLGI 484
+T + V G + L CKA A + + G + +E + ++ L I
Sbjct: 505 KRTELTV-GESIVLNCKAIHDASLDVTFYWTLKGQPIDFEEEGGHFESIRAQASSADLMI 563
Query: 485 RDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTI---EKKGSRVTFTCQA 541
R++ GRY C ++V+ A L V+ GP + E S T +
Sbjct: 564 RNILLMHAGRYGCRVQTTADSVSDEAELLVRGPP----GPPGIVIVEEITESTATLSWSP 619
Query: 542 SFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVE 601
+ D + P ++ R LG + + ++ ++ + + + E VV
Sbjct: 620 AAD-NHSPISSYNLQARSPFSLGWQTVKTVPE--IITGDMESAMAVDLNPWVEYEFRVVA 676
Query: 602 SRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAEDHNAPI--EKYDIEFEDKE--- 656
+ + G P R++ ++ + + VS H I E EF++ E
Sbjct: 677 TNP--IGTGDPSTPSRMIRTNEAVPKTAPTNVSGRSGRRHELVIAWEPVSEEFQNGEGFG 734
Query: 657 ----MAPE--KWYSLGKVPGNQTSTTL----KLSPYVHYTFRVTAINKYGPGEPSPVSET 706
P + + V ++ S + + P + +V N G G P S+
Sbjct: 735 YIVAFRPNGTRGWKEKMVTSSEASKFIYRDESVPPLTPFEVKVGVYNNKGDG---PFSQI 791
Query: 707 VV--TPEAAPEKNPVDVKGEGNETTNMVITWKPLRWMDWNAPQVQYRVQWRPQGTR-GPW 763
VV + E P P DVK + +++ WK ++ RPQG G W
Sbjct: 792 VVICSAEGEPSAAPTDVKATSVSVSEILVAWKHIK-----------ESLGRPQGFEVGYW 840
Query: 764 QEQIVSDP-----------FLVVSNTSTFVPYEIKVQAVNSQGKGPEPQVTIGYSGEDYP 812
++ D F++++ Y V+A N G GP + + P
Sbjct: 841 KDMEQEDTAETVKTRGNESFVILTGLEGNTLYHFTVRAYNGAGYGPPSSEVSATTKKSPP 900
Query: 813 QAIPELEGIEILNSSAVLVKWRPVDLAQVKGHLRGYNVTYWREGSQRKHSKRHI---HKD 869
P E S V + W PV + + GY V Y +EG HS + K
Sbjct: 901 SQAPSNLRWE-QQGSQVSLGWEPVIPLANESEVVGYKVFYRQEG----HSNSQVIETQKL 955
Query: 870 HVVVPANTTSVILSGLRPYSSYHLEVQAFNGRGSGPAS 907
VVP V Y +EV+A++ G G AS
Sbjct: 956 QAVVPLPDAGV----------YIIEVRAYSEGGDGTAS 983
Score = 36.6 bits (83), Expect = 0.16
Identities = 31/139 (22%), Positives = 55/139 (39%), Gaps = 12/139 (8%)
Query: 34 PPVITEQSPRRLVVFPTDDISLKCEASGKPEVQFRWTRDGVHFKPKEELGVTVYQSPHSG 93
P Q + ++V ++ ++C+ G P+ W + + + + + G
Sbjct: 406 PTFALNQLKKTIIVTKDQEVVIECKPQGSPKPTISWKKGDRAVRENKRIAIL-----PDG 460
Query: 94 SFTITGNNSNFAQRFQGIYRCFASNKLGTAMSHEIRLMAEGAPKWPKETVKPVEVEEGES 153
S I N ++ +G Y C N G+A I ++ P + T K E+ GES
Sbjct: 461 SLRIL----NASKSDEGKYVCRGENVFGSA--EIIASLSVKEPTRIELTPKRTELTVGES 514
Query: 154 VVLPCNPPPSAE-PLRIYW 171
+VL C A + YW
Sbjct: 515 IVLNCKAIHDASLDVTFYW 533
Score = 33.5 bits (75), Expect = 1.3
Identities = 31/135 (22%), Positives = 60/135 (44%), Gaps = 19/135 (14%)
Query: 916 GVPGHPEALHLECQSNTSLLLRWQPPLSHNGVLTGYVLSYH-PLDEGGKGQLSFNLRDPE 974
G PG P + +E + ++ L W P ++ ++ Y L P G + + PE
Sbjct: 595 GPPGPPGIVIVEEITESTATLSWSPAADNHSPISSYNLQARSPFSLGWQTVKTV----PE 650
Query: 975 LRTHNL-----TDLSPHLRYRFQLQATTKEGPGE-----AIVREGGTMALSGISDFGNIS 1024
+ T ++ DL+P + Y F++ AT G G+ ++R + + + N+S
Sbjct: 651 IITGDMESAMAVDLNPWVEYEFRVVATNPIGTGDPSTPSRMIRTNEAVPKTAPT---NVS 707
Query: 1025 ATAGENYS-VVSWVP 1038
+G + V++W P
Sbjct: 708 GRSGRRHELVIAWEP 722
>gi|4827022 contactin 2 precursor [Homo sapiens]
Length = 1040
Score = 386 bits (992), Expect = e-107
Identities = 296/945 (31%), Positives = 430/945 (45%), Gaps = 74/945 (7%)
Query: 46 VVFPTDD----ISLKCEASGKPEVQFRWTRDGVHFKPKEELGVTVYQSPHSGSFTITGN- 100
V+FP + + L C A P +RW +G K + P S + GN
Sbjct: 46 VLFPEESTEEQVLLACRARASPPATYRWKMNGTEMKLE----------PGSRHQLVGGNL 95
Query: 101 ---NSNFAQRFQGIYRCFASNKLGTAMSHEIRLMAEGAPKWPKETVKPVEVEEGESVVLP 157
N AQ G+Y+C ASN +GT +S E L ++ KE PV+ EG V+LP
Sbjct: 96 VIMNPTKAQD-AGVYQCLASNPVGTVVSREAILRFGFLQEFSKEERDPVKAHEGWGVMLP 154
Query: 158 CNPPPSAEPLRIYWMNSKILH-IKQDERVTMGQN-GNLYFANVLTSDNHSDYIC----HA 211
CNPP L W+ ++ + I D R + Q GNLY A SD +Y C H
Sbjct: 155 CNPPAHYPGLSYRWLLNEFPNFIPTDGRHFVSQTTGNLYIARTNASDL-GNYSCLATSHM 213
Query: 212 HFPGTRTIIQK-EPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFP 270
F T+++ K ++L + T + + FP + AL GQ + LEC A G P
Sbjct: 214 DF-STKSVFSKFAQLNLAAEDTR-LFAPSIKARFPAET----YALVGQQVTLECFAFGNP 267
Query: 271 TPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVE 330
P IKW + G + T + TLQ+ V ED+G Y C AENS G + V+
Sbjct: 268 VPRIKWRKVDGSLSPQWTTAE---PTLQIPSVSFEDEGTYECEAENSKGRDTVQGRIIVQ 324
Query: 331 AAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALI 390
A P WL G R C G+P+P V W NG P LA + + G L
Sbjct: 325 AQPEWLKVISDTEADIGSNLRWGCAAAGKPRPTVRWLRNGEP---LASQNRVEVLAGDLR 381
Query: 391 LSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQL-PAKILTADNQTYMAVQGSTAYLLCK 449
S + D+ + QC A N+HG + A+A + V L P L + A +G + C+
Sbjct: 382 FSKLSLEDSGMYQCVAENKHGTIYASAELAVQALAPDFRLNPVRRLIPAARGGEILIPCQ 441
Query: 450 AFGAPVPSVQWLDEDGTTVL-QDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTI 508
AP V W GT +L R +GTL IR++ +D G+Y C A N
Sbjct: 442 PRAAPKAVVLW--SKGTEILVNSSRVTVTPDGTLIIRNISRSDEGKYTCFAENFMGKANS 499
Query: 509 MANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDK 568
L V+DAT+IT P S G +T C AS DP++ + TW D +
Sbjct: 500 TGILSVRDATKITLAPSSADINLGDNLTLQCHASHDPTMDLTFTWTLDDFPIDFDKPGGH 559
Query: 569 YFIED-----GRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDL 623
Y + G L I + G Y+C+A T +D A +LV G PGP +V+ D
Sbjct: 560 YRRTNVKETIGDLTILNAQLRHGGKYTCMAQTVVDSASKEATVLVRGPPGPPGGVVVRD- 618
Query: 624 HLLTQSQVRVSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGN-----QTSTTLK 678
+ + +++SWS D+++PI KY ++ KW + P N +T+ L
Sbjct: 619 --IGDTTIQLSWSRGFDNHSPIAKYTLQARTPPAG--KWKQVRTNPANIEGNAETAQVLG 674
Query: 679 LSPYVHYTFRVTAINKYGPGEPSPVSETVVTPEAAPEKNPVDVKGEGNETTNMVITWKPL 738
L+P++ Y FRV A N G GEPS S + T EAAP P + G G +++ W P+
Sbjct: 675 LTPWMDYEFRVIASNILGTGEPSGPSSKIRTREAAPSVAPSGLSGGGGAPGELIVNWTPM 734
Query: 739 RWMDWNAPQVQYRVQWRPQGTRGPWQEQIV---SDPFLVVSNTST--FVPYEIKVQAVNS 793
N Y + +R QG+ WQ V + V SN S + P+E+K+++ N
Sbjct: 735 SREYQNGDGFGYLLSFRRQGST-HWQTARVPGADAQYFVYSNESVRPYTPFEVKIRSYNR 793
Query: 794 QGKGPEPQVTIGYSGEDYPQAIPELEGIEILNSSAVLVKWRPVDLAQVKGHLRGYNVTYW 853
+G GPE + YS E+ P+ P + ++SS + V W PV + G L GY + YW
Sbjct: 794 RGDGPESLTALVYSAEEEPRVAPTKVWAKGVSSSEMNVTWEPVQ-QDMNGILLGYEIRYW 852
Query: 854 REGSQRKHSKRHIHKDHVVVPANTTSVILSGLRPYSSYHLEVQAFNGRGSGPAS-EFTFS 912
+ G + + D V TS +SGL P + YH+ V+A+N G+GPAS +
Sbjct: 853 KAGDKEAAA------DRVRTAGLDTSARVSGLHPNTKYHVTVRAYNRAGTGPASPSANAT 906
Query: 913 TPEGVPGHPEALHLECQSNTSLLLRWQP--PLSHNGVLTGYVLSY 955
T + P P S++SL ++W P P + +TGY + Y
Sbjct: 907 TMKPPPRRPPGNISWTFSSSSLSIKWDPVVPFRNESAVTGYKMLY 951
Score = 65.1 bits (157), Expect = 4e-10
Identities = 80/379 (21%), Positives = 142/379 (37%), Gaps = 37/379 (9%)
Query: 35 PVITEQSPRRLVVFPTDDISLKCEASGKPEVQFRWTRDGVHFKPKEELGVTVYQSPHSGS 94
P I + P ++L+C A G P + +W + P+ Q P S S
Sbjct: 239 PSIKARFPAETYALVGQQVTLECFAFGNPVPRIKWRKVDGSLSPQWTTAEPTLQIP-SVS 297
Query: 95 FTITGNNSNFAQRFQGIYRCFASNKLGTAMSHEIRLMAEGAPKWPKETVKPVEVEEGESV 154
F +G Y C A N G + + R++ + P+W K + E + G ++
Sbjct: 298 F-----------EDEGTYECEAENSKGRD-TVQGRIIVQAQPEWLK-VISDTEADIGSNL 344
Query: 155 VLPCNPPPSAEPLRIYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAHFP 214
C P + N + L + V G+L F+ L+ ++ Y C A
Sbjct: 345 RWGCAAAGKPRPTVRWLRNGEPLASQNRVEVLA---GDLRFSK-LSLEDSGMYQCVAE-N 399
Query: 215 GTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTI 274
TI + ++ A + ++ RL + A +G +++ C P +
Sbjct: 400 KHGTIYASAELAVQALAPDFRLNPVRRL---------IPAARGGEILIPCQPRAAPKAVV 450
Query: 275 KWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPY 334
W + + + + TL + + D+G+Y C AEN +G A ++V A
Sbjct: 451 LWSKGTEILVNSSRVTVTPDGTLIIRNISRSDEGKYTCFAENFMGKANSTGILSVRDATK 510
Query: 335 WLHKPQSHLYGPGETARLDCQVQGRPQPEV--TWRINGIPVEELAKDQKYRIQRGALILS 392
P S G+ L C P ++ TW ++ P++ YR +
Sbjct: 511 ITLAPSSADINLGDNLTLQCHASHDPTMDLTFTWTLDDFPIDFDKPGGHYR-------RT 563
Query: 393 NVQPSDTMVTQCEARNRHG 411
NV+ + +T A+ RHG
Sbjct: 564 NVKETIGDLTILNAQLRHG 582
>gi|7657361 contactin 6 [Homo sapiens]
Length = 1028
Score = 379 bits (974), Expect = e-105
Identities = 281/977 (28%), Positives = 452/977 (46%), Gaps = 61/977 (6%)
Query: 5 LRYVWPLLLCSPCLLIQIPEEYEGHHVMEPPVITEQSPRRLVVFPTD----DISLKCEAS 60
+R +W L++ P + G ++ P+ T++ V+FP D ++ L C A+
Sbjct: 1 MRLLWKLVILLPLI-----NSSAGDGLLSRPIFTQEPHD--VIFPLDLSKSEVILNCAAN 53
Query: 61 GKPEVQFRWTRDGVHFKPKEELGVTVYQSPHSGSFTITGNNSNFAQRFQGIYRCFASNKL 120
G P +RW ++G + ++ + GS I NS + G+Y+C A+N L
Sbjct: 54 GYPSPHYRWKQNGTDI----DFTMSYHYRLDGGSLAI---NSPHTDQDIGMYQCLATNLL 106
Query: 121 GTAMSHEIRLMAEGAPKWPKETVKPVEVEEGESVVLPCNPPPSAEPLRIYW-MNSKILHI 179
GT +S + +L + +T V V EG+ VVL C PPP L W N L++
Sbjct: 107 GTILSRKAKLQFAYIEDFETKTRSTVSVREGQGVVLLCGPPPHFGDLSYAWTFNDNPLYV 166
Query: 180 KQDERVTMGQN-GNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLRVKATNSMIDR 238
++D R + Q GNLY A V SD +Y C + +Q P L + M +
Sbjct: 167 QEDNRRFVSQETGNLYIAKVEPSDV-GNYTCFITNKEAQRSVQGPPTPLVQRTDGVMGEY 225
Query: 239 KPRL--LFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKT 296
+P++ FP + A + + LEC A G P P I W R G +V Y
Sbjct: 226 EPKIEVRFPET----IQAAKDSSVKLECFALGNPVPDISWRRLDGSPLPGKVKYSKSQAI 281
Query: 297 LQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQV 356
L++ +ED+G Y C+A N G + A P W K Q+ + +C+
Sbjct: 282 LEIPNFQQEDEGFYECIASNLRGRNLAKGQLIFYAPPEWEQKIQNTHLSIYDNLLWECKA 341
Query: 357 QGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLAN 416
G+P P TW NG E L +++ +I+ G LI++ + SD+ V QC A N++ ++ AN
Sbjct: 342 SGKPNPWYTWLKNG---ERLNPEERIQIENGTLIITMLNVSDSGVYQCAAENKYQIIYAN 398
Query: 417 AYIYVVQLPAKILTADNQTYMAVQ-GSTAYLLCKAFGAPVPSVQWLDEDGT-TVLQDERF 474
A + V+ + + VQ G + CK P ++ W + GT T+ Q +R
Sbjct: 399 AELRVLASAPDFSKSPVKKKSFVQVGGDIVIGCKPNAFPRAAISW--KRGTETLRQSKRI 456
Query: 475 FPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSR 534
F +G+L I ++ +D G Y C+A N +L VK+ T IT P G
Sbjct: 457 FLLEDGSLKIYNITRSDAGSYTCIATNQFGTAKNTGSLIVKERTVITVPPSKMDVTVGES 516
Query: 535 VTFTCQASFDPSLQPSITW--RGDGRDLQE-LGDSDKYFIED-GRLVIHSLDYSDQGNYS 590
+ CQ S DPS++ W GD DL++ + ++ E G L+I ++ G Y
Sbjct: 517 IVLPCQVSHDPSIEVVFVWFFNGDVIDLKKGVAHFERIGGESVGDLMIRNIQLHHSGKYL 576
Query: 591 CVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAEDHNAPIEKYDI 650
C T L+ + + A ++V G PGP + + D+ T ++SW D+N+PI+ + I
Sbjct: 577 CTVQTTLESLSAVADIIVRGPPGPPEDVQVEDISSTTS---QLSWRAGPDNNSPIQIFTI 633
Query: 651 EFEDKEMAPEKWYSLGKVP-----GNQTSTTLKLSPYVHYTFRVTAINKYGPGEPSPVSE 705
+ + W ++ VP +T + LSP+V Y FRV A N G GEPS SE
Sbjct: 634 --QTRTPFSVGWQAVATVPEILNGKTYNATVVGLSPWVEYEFRVVAGNSIGIGEPSEPSE 691
Query: 706 TVVTPEAAPEKNPVDVKGEGNETTNMVITWKPLRWMDWNAPQVQYRVQWRPQGTRGPWQE 765
+ T + P PV++ G G + +VITW+ + N Y + +RP G+ +E
Sbjct: 692 LLRTKASVPVVAPVNIHGGGGSRSELVITWESIPEELQNGEGFGYIIMFRPVGSTTWSKE 751
Query: 766 QI--VSDPFLVVSNTS--TFVPYEIKVQAVNSQGKGPEPQVTIGYSGEDYPQAIPELEGI 821
++ V V N S P+E+KV N++G+G VTI YSGED PQ P +
Sbjct: 752 KVSSVESSRFVYRNESIIPLSPFEVKVGVYNNEGEGSLSTVTIVYSGEDEPQLAPRGTSL 811
Query: 822 EILNSSAVLVKWRPVDLAQVKGHLRGYNVTYWREGSQRKHSKRHIHKDHVVVPANTTSVI 881
+ ++S + V W + + G + GY V YW + S+ + + V N T+
Sbjct: 812 QSFSASEMEVSWNAIAWNRNTGRVLGYEVLYWTDDSKESMIGK------IRVSGNVTTKN 865
Query: 882 LSGLRPYSSYHLEVQAFNGRGSGPAS-EFTFSTPEGVPGHPEALHLECQSNTSLLLRWQ- 939
++GL+ + Y V+A+N G+GP+S +T + P P A +N+ L L W+
Sbjct: 866 ITGLKANTIYFASVRAYNTAGTGPSSPPVNVTTKKSPPSQPPANIAWKLTNSKLCLNWEH 925
Query: 940 -PPLSHNGVLTGYVLSY 955
+ + + GY + Y
Sbjct: 926 VKTMENESEVLGYKILY 942
Score = 82.4 bits (202), Expect = 2e-15
Identities = 141/684 (20%), Positives = 265/684 (38%), Gaps = 66/684 (9%)
Query: 260 LVLECIAEGFPTPTIKWLRPSGPM-PADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSL 318
L+ EC A G P P WL+ + P +R+ +N + +L V D G Y+C AEN
Sbjct: 335 LLWECKASGKPNPWYTWLKNGERLNPEERIQIENGTLIITMLNVS--DSGVYQCAAENKY 392
Query: 319 GSA-RHAYYVTVEAAPYWLHKP--QSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEE 375
+A + +AP + P + G + C+ P+ ++W+ E
Sbjct: 393 QIIYANAELRVLASAPDFSKSPVKKKSFVQVGGDIVIGCKPNAFPRAAISWKRG---TET 449
Query: 376 LAKDQK-YRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQ 434
L + ++ + ++ G+L + N+ SD C A N+ G + V + ++T
Sbjct: 450 LRQSKRIFLLEDGSLKIYNITRSDAGSYTCIATNQFGTAKNTGSLIVKE--RTVITVPPS 507
Query: 435 TYMAVQGSTAYLLCKAFGAPVPSVQ--WLDEDGTTVLQD-----ERFFPYANGTLGIRDL 487
G + L C+ P V W L+ ER + G L IR++
Sbjct: 508 KMDVTVGESIVLPCQVSHDPSIEVVFVWFFNGDVIDLKKGVAHFERIGGESVGDLMIRNI 567
Query: 488 QANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPR-STIEKKGSRVTFTCQASFDPS 546
Q + +G+Y C +++ +A++ V+ + + I S++++ +
Sbjct: 568 QLHHSGKYLCTVQTTLESLSAVADIIVRGPPGPPEDVQVEDISSTTSQLSWRAGPDNNSP 627
Query: 547 LQP---------SITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTEL 597
+Q S+ W+ + E+ + Y + L + + VA +
Sbjct: 628 IQIFTIQTRTPFSVGWQAVAT-VPEILNGKTY-----NATVVGLSPWVEYEFRVVAGNSI 681
Query: 598 DVVESRAQLLVVGSPGPVPRLVLSDLHLL--TQSQVRVSWS--PAEDHNAPIEKYDIEFE 653
+ E ++ + VP + ++H ++S++ ++W P E N Y I F
Sbjct: 682 GIGEPSEPSELLRTKASVPVVAPVNIHGGGGSRSELVITWESIPEELQNGEGFGYIIMF- 740
Query: 654 DKEMAPEKWYSLGKVPGNQTSTTL----KLSPYVHYTFRVTAINKYGPGEPSPVSETVVT 709
+ + W S KV ++S + + P + +V N G G S V+ V +
Sbjct: 741 -RPVGSTTW-SKEKVSSVESSRFVYRNESIIPLSPFEVKVGVYNNEGEGSLSTVT-IVYS 797
Query: 710 PEAAPEKNPVDVKGEGNETTNMVITWKPLRWMDWNAPQVQYRVQWRPQGTRGPWQEQIVS 769
E P+ P + + M ++W + W + Y V + ++ +I
Sbjct: 798 GEDEPQLAPRGTSLQSFSASEMEVSWNAIAWNRNTGRVLGYEVLYWTDDSKESMIGKIRV 857
Query: 770 DPFLVVSNTSTFVP---YEIKVQAVNSQGKGPE-PQVTIGYSGEDYPQAIPELEGIEILN 825
+ N + Y V+A N+ G GP P V + + + P + P L
Sbjct: 858 SGNVTTKNITGLKANTIYFASVRAYNTAGTGPSSPPVNV--TTKKSPPSQPPANIAWKLT 915
Query: 826 SSAVLVKWRPVDLAQVKGHLRGYNVTYWREGSQRKHSKRHIHKDHVVVPANTTSVILSGL 885
+S + + W V + + + GY + Y Q + SK HI + N TS L L
Sbjct: 916 NSKLCLNWEHVKTMENESEVLGYKILY----RQNRQSKTHI------LETNNTSAEL--L 963
Query: 886 RPY-SSYHLEVQAFNGRGSGPASE 908
P+ Y +E++ + G G +SE
Sbjct: 964 VPFEEDYLIEIRTVSDGGDGSSSE 987
>gi|28373122 contactin 4 isoform a precursor [Homo sapiens]
Length = 1026
Score = 377 bits (969), Expect = e-104
Identities = 286/977 (29%), Positives = 445/977 (45%), Gaps = 63/977 (6%)
Query: 5 LRYVWPLLLCSPCLLIQIPEEYEGHHVMEPPVITEQSPRRLVVFPTDD----ISLKCEAS 60
+R W LL+ +L + + P I E SP V+FP D + L CE
Sbjct: 1 MRLPWELLVLQSFILCLADDST----LHGPIFIQEPSP---VMFPLDSEEKKVKLNCEVK 53
Query: 61 GKPEVQFRWTRDGVHFKPKEELGVTVYQSPHSGSFTITGNNSNFAQRFQGIYRCFASNKL 120
G P+ RW +G + G+ S GS I NN N Q G Y+C A+N
Sbjct: 54 GNPKPHIRWKLNGTDV----DTGMDFRYSVVEGSLLI--NNPNKTQD-AGTYQCTATNSF 106
Query: 121 GTAMSHEIRLMAEGAPKWPKETVKPVEVEEGESVVLPCNPPPSAEPLRIYWMNSKILHIK 180
GT +S E +L + T V V G+ +VL C PPP + L W+ ++ +
Sbjct: 107 GTIVSREAKLQFAYLDNFKTRTRSTVSVRRGQGMVLLCGPPPHSGELSYAWIFNEYPSYQ 166
Query: 181 QDERVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLRVKATNSMIDRKP 240
+ R + GNLY A V SD +Y C T + P L ++ M + +P
Sbjct: 167 DNRRFVSQETGNLYIAKVEKSDV-GNYTCVVTNTVTNHKVLGPPTPLILRNDGVMGEYEP 225
Query: 241 RL--LFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQ 298
++ FP + +G + LEC A G P PTI W R G A + N L+
Sbjct: 226 KIEVQFPET----VPTAKGATVKLECFALGNPVPTIIWRRADGKPIARKARRHKSNGILE 281
Query: 299 LLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQVQG 358
+ +ED G Y C+AENS G +T A P W+ K E +C+ G
Sbjct: 282 IPNFQQEDAGLYECVAENSRGKNVARGQLTFYAQPNWIQKINDIHVAMEENVFWECKANG 341
Query: 359 RPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAY 418
RP+P W NG P+ L +D + +I++G L ++ V SD + QC A N+HG++ +NA
Sbjct: 342 RPKPTYKWLKNGEPL--LTRD-RIQIEQGTLNITIVNLSDAGMYQCLAENKHGVIFSNAE 398
Query: 419 IYVVQL-PAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVL-QDERFFP 476
+ V+ + P T + + G + CK +P P W + G +L ++ER
Sbjct: 399 LSVIAVGPDFSRTLLKRVTLVKVGGEVVIECKPKASPKPVYTW--KKGRDILKENERITI 456
Query: 477 YANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVT 536
+G L I ++ +D G Y C+A N + NL VKD T++ P S G +
Sbjct: 457 SEDGNLRIINVTKSDAGSYTCIATNHFGTASSTGNLVVKDPTRVMVPPSSMDVTVGESIV 516
Query: 537 FTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR-----LVIHSLDYSDQGNYSC 591
CQ + D SL TW +G + D D + G+ L+I ++ G Y C
Sbjct: 517 LPCQVTHDHSLDIVFTWSFNGHLIDFDRDGDHFERVGGQDSAGDLMIRNIQLKHAGKYVC 576
Query: 592 VASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAEDHNAPIEKYDIE 651
+ T +D + + A L+V G PGP + + + +T + ++SW P D+++PI Y I
Sbjct: 577 MVQTSVDRLSAAADLIVRGPPGPPEAVTIDE---ITDTTAQLSWRPGPDNHSPITMYVI- 632
Query: 652 FEDKEMAPEKWYSLGKVP-----GNQTSTTLKLSPYVHYTFRVTAINKYGPGEPSPVSET 706
+ + W ++ VP T+T + L+P+V Y FR A N G GEPS SE
Sbjct: 633 -QARTPFSVGWQAVSTVPELIDGKTFTATVVGLNPWVEYEFRTVAANVIGIGEPSRPSEK 691
Query: 707 VVTPEAAPEKNPVDVKGEGNETTNMVITWKPLRWMDWNAPQVQYRVQWRPQGTRGPWQEQ 766
T EA PE P +V G G + +VITW+ + N Y V +RP G + W
Sbjct: 692 RRTEEALPEVTPANVSGGGGSKSELVITWETVPEELQNGRGFGYVVAFRPYG-KMIWMLT 750
Query: 767 IVSD---PFLVVSNTST--FVPYEIKVQAVNSQGKGPEPQVTIGYSGEDYPQAIPELEGI 821
+++ V N S F P+E+KV N++G+GP T+ YS E+ P P
Sbjct: 751 VLASADASRYVFRNESVHPFSPFEVKVGVFNNKGEGPFSPTTVVYSAEEEPTKPPASIFA 810
Query: 822 EILNSSAVLVKWRPVDLAQVKGHLRGYNVTYWREGSQRKHSKRHIHKDHVVVPANTTSVI 881
L+++ + V W L + +G ++GY V YWR + +++++ + N TS
Sbjct: 811 RSLSATDIEVFWAS-PLEKNRGRIQGYEVKYWRHEDKEENARK------IRTVGNQTSTK 863
Query: 882 LSGLRPYSSYHLEVQAFNGRGSGPAS-EFTFSTPEGVPGHPEALHLECQSNTSLLLRWQ- 939
++ L+ YHL V+A+N G+GP+S +T + P P + S++ ++L W
Sbjct: 864 ITNLKGSVLYHLAVKAYNSAGTGPSSATVNVTTRKPPPSQPPGNIIWNSSDSKIILNWDQ 923
Query: 940 -PPLSHNGVLTGYVLSY 955
L + + GY + Y
Sbjct: 924 VKALDNESEVKGYKVLY 940
>gi|28373117 contactin 1 isoform 1 precursor [Homo sapiens]
Length = 1018
Score = 345 bits (885), Expect = 2e-94
Identities = 280/967 (28%), Positives = 420/967 (43%), Gaps = 86/967 (8%)
Query: 28 GHHVMEP-----PVITEQSPRRLVVFPTDD----ISLKCEASGKPEVQFRWTRDGVHFKP 78
GH V E P+ EQ ++P + +SL C A P ++W +
Sbjct: 29 GHGVSEEDKGFGPIFEEQPIN--TIYPEESLEGKVSLNCRARASPFPVYKWRMNN----- 81
Query: 79 KEELGVTVYQSPHSGSFTITGNNSNFAQRFQGIYRCFASNKLGTAMSHEIRLMAEGAPKW 138
++ +T + G + N Q+ GIY C ASN G S E L +
Sbjct: 82 -GDVDLTSDRYSMVGGNLVINNPDK--QKDAGIYYCLASNNYGMVRSTEATLSFGYLDPF 138
Query: 139 PKETVKPVEVEEGESVVLPCNPPPS-AEPLRIYWM-NSKILHIKQDERVTMGQ-NGNLYF 195
P E V V+EG+ +VL C+PP + L W+ N + I D+R + Q NGNLY
Sbjct: 139 PPEERPEVRVKEGKGMVLLCDPPYHFPDDLSYRWLLNEFPVFITMDKRRFVSQTNGNLYI 198
Query: 196 ANVLTSDNHSDYICHAHFPG-TRTIIQKE----PIDLRVKATNSMIDRKPRLLFPTNSSS 250
ANV SD +Y C P T+++ K PI R KP
Sbjct: 199 ANVEASDK-GNYSCFVSSPSITKSVFSKFIPLIPIPERTT--------KPYPADIVVQFK 249
Query: 251 HLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEY 310
+ AL GQ + LEC A G P P I+W + PMP+ L++ + ED+G Y
Sbjct: 250 DVYALMGQNVTLECFALGNPVPDIRWRKVLEPMPST-AEISTSGAVLKIFNIQLEDEGIY 308
Query: 311 RCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRING 370
C AEN G +H + V+A P W+ G C G+P P + W NG
Sbjct: 309 ECEAENIRGKDKHQARIYVQAFPEWVEHINDTEVDIGSDLYWPCVATGKPIPTIRWLKNG 368
Query: 371 IPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQL-PAKIL 429
Y +G L L +V + + QC A N +G + ANA + ++ L P +
Sbjct: 369 -----------YAYHKGELRLYDVTFENAGMYQCIAENTYGAIYANAELKILALAPTFEM 417
Query: 430 TADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTT-VLQDERFFPYANGTLGIRDLQ 488
+ +A +G + CK AP P W GT ++ R + +G+L I ++
Sbjct: 418 NPMKKKILAAKGGRVIIECKPKAAPKPKFSW--SKGTEWLVNSSRILIWEDGSLEINNIT 475
Query: 489 ANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQ 548
ND G Y C A N++ L + D T+I P + G T C ASFDP+L
Sbjct: 476 RNDGGIYTCFAENNRGKANSTGTLVITDPTRIILAPINADITVGENATMQCAASFDPALD 535
Query: 549 PSITWRGDGRDLQELGDSDKY---FIED--GRLVIHSLDYSDQGNYSCVASTELDVVESR 603
+ W +G + ++ Y F+ D G L+I + G Y+C A T +D +
Sbjct: 536 LTFVWSFNGYVIDFNKENIHYQRNFMLDSNGELLIRNAQLKHAGRYTCTAQTIVDNSSAS 595
Query: 604 AQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAEDHNAPIEKYDIEFEDKEMAPEKWY 663
A L+V G PGP L + D+ + V ++WS D+++PI KY I+ K + + W
Sbjct: 596 ADLVVRGPPGPPGGLRIEDIRA---TSVALTWSRGSDNHSPISKYTIQ--TKTILSDDWK 650
Query: 664 SLGKVP----GN-QTSTTLKLSPYVHYTFRVTAINKYGPGEPSPVSETVVTPEAAPEKNP 718
P GN + + + L P++ Y FRV A N G GEPS S + T AAP P
Sbjct: 651 DAKTDPPIIEGNMEAARAVDLIPWMEYEFRVVATNTLGRGEPSIPSNRIKTDGAAPNVAP 710
Query: 719 VDVKGEGNETTNMVITWKPLRWMDWNAPQVQYRVQWRPQGTRGPWQEQIVSDPFL--VVS 776
DV G G + ITW PL Y V ++P W++ V++P V
Sbjct: 711 SDVGGGGGRNRELTITWAPLSREYHYGNNFGYIVAFKPFDGE-EWKKVTVTNPDTGRYVH 769
Query: 777 NTSTFVP---YEIKVQAVNSQGKGPEPQVTIGYSGEDYPQAIPELEGIEILNSSAVLVKW 833
T P +++KV+A N++G GP V + S +D P P G+++L+SS + V W
Sbjct: 770 KDETMSPSTAFQVKVKAFNNKGDGPYSLVAVINSAQDAPSEAPTEVGVKVLSSSEISVHW 829
Query: 834 RPVDLAQVKGHLRGYNVTYWREGSQRKHSKRHIHKDHVVVPANTTSVILSGLRPYSSYHL 893
V ++ + Y + YW + + + R V V + S L L P + Y +
Sbjct: 830 EHV----LEKIVESYQIRYWAAHDKEEAANR------VQVTSQEYSARLENLLPDTQYFI 879
Query: 894 EVQAFNGRGSGPASEFTFS-TPEGVPGHPEALHLECQSNTSLLLRWQ--PPLSHNGVLTG 950
EV A N G GP S+ + T + P P + +S + ++ W LS+ +TG
Sbjct: 880 EVGACNSAGCGPPSDMIEAFTKKAPPSQPPRIISSVRSGSRYIITWDHVVALSNESTVTG 939
Query: 951 YVLSYHP 957
Y + Y P
Sbjct: 940 YKVLYRP 946
Score = 41.2 bits (95), Expect = 0.006
Identities = 54/217 (24%), Positives = 84/217 (38%), Gaps = 31/217 (14%)
Query: 625 LLTQSQVRVSWSPAEDHNAPIEKYDIEF---EDKEMAPEKWYSLGKVPGNQTSTTLK-LS 680
+L+ S++ V W + +E Y I + DKE A + +V + S L+ L
Sbjct: 819 VLSSSEISVHWEHVLEKI--VESYQIRYWAAHDKEEAANRV----QVTSQEYSARLENLL 872
Query: 681 PYVHYTFRVTAINKYGPGEPSPVSETVVTPEAAPEKNPVDVKGEGNETTNMVITWKPLRW 740
P Y V A N G G PS + E + AP P + + +ITW +
Sbjct: 873 PDTQYFIEVGACNSAGCGPPSDMIEAFT--KKAPPSQPPRIISSVRSGSRYIITWDHVVA 930
Query: 741 MDWNAPQVQYRVQWRPQGTRGPWQEQIVSDPFLVVSNTSTFVP------YEIKVQAVNSQ 794
+ + Y+V +RP G S VP Y ++V+A +
Sbjct: 931 LSNESTVTGYKVLYRPDGQH--------DGKLYSTHKHSIEVPIPRDGEYVVEVRAHSDG 982
Query: 795 GKGPEPQVTIGYSGEDYPQAIPELEGIEILNSSAVLV 831
G G QV I + P P L G+ +L + +LV
Sbjct: 983 GDGVVSQVKISGA----PTLSPSLLGL-LLPAFGILV 1014
Score = 33.5 bits (75), Expect = 1.3
Identities = 33/140 (23%), Positives = 53/140 (37%), Gaps = 7/140 (5%)
Query: 869 DHVVVPANTTSVILSGLRPYSSYHLEVQAFN--GRGSGPASEFTFSTPEGVPG-HPEALH 925
D ++ N + L P+ Y V A N GRG T P P +
Sbjct: 655 DPPIIEGNMEAARAVDLIPWMEYEFRVVATNTLGRGEPSIPSNRIKTDGAAPNVAPSDVG 714
Query: 926 LECQSNTSLLLRWQPPLS---HNGVLTGYVLSYHPLDEGGKGQLSFNLRDPELRTHNLTD 982
N L + W P LS H G GY++++ P D +++ D H
Sbjct: 715 GGGGRNRELTITWAP-LSREYHYGNNFGYIVAFKPFDGEEWKKVTVTNPDTGRYVHKDET 773
Query: 983 LSPHLRYRFQLQATTKEGPG 1002
+SP ++ +++A +G G
Sbjct: 774 MSPSTAFQVKVKAFNNKGDG 793
>gi|28373119 contactin 1 isoform 2 precursor [Homo sapiens]
Length = 1007
Score = 345 bits (885), Expect = 2e-94
Identities = 281/979 (28%), Positives = 426/979 (43%), Gaps = 85/979 (8%)
Query: 11 LLLCSPCLLIQIPEEYEGHHVMEPPVITEQSPRRLVVFPTDD----ISLKCEASGKPEVQ 66
L++ S + + EE +G P+ EQ ++P + +SL C A P
Sbjct: 10 LVIISITTCLAVSEEDKGFG----PIFEEQPIN--TIYPEESLEGKVSLNCRARASPFPV 63
Query: 67 FRWTRDGVHFKPKEELGVTVYQSPHSGSFTITGNNSNFAQRFQGIYRCFASNKLGTAMSH 126
++W + ++ +T + G + N Q+ GIY C ASN G S
Sbjct: 64 YKWRMNN------GDVDLTSDRYSMVGGNLVINNPDK--QKDAGIYYCLASNNYGMVRST 115
Query: 127 EIRLMAEGAPKWPKETVKPVEVEEGESVVLPCNPPPS-AEPLRIYWM-NSKILHIKQDER 184
E L +P E V V+EG+ +VL C+PP + L W+ N + I D+R
Sbjct: 116 EATLSFGYLDPFPPEERPEVRVKEGKGMVLLCDPPYHFPDDLSYRWLLNEFPVFITMDKR 175
Query: 185 VTMGQ-NGNLYFANVLTSDNHSDYICHAHFPG-TRTIIQKE----PIDLRVKATNSMIDR 238
+ Q NGNLY ANV SD +Y C P T+++ K PI R
Sbjct: 176 RFVSQTNGNLYIANVEASDK-GNYSCFVSSPSITKSVFSKFIPLIPIPERTT-------- 226
Query: 239 KPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQ 298
KP + AL GQ + LEC A G P P I+W + PMP+ L+
Sbjct: 227 KPYPADIVVQFKDVYALMGQNVTLECFALGNPVPDIRWRKVLEPMPST-AEISTSGAVLK 285
Query: 299 LLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQVQG 358
+ + ED+G Y C AEN G +H + V+A P W+ G C G
Sbjct: 286 IFNIQLEDEGIYECEAENIRGKDKHQARIYVQAFPEWVEHINDTEVDIGSDLYWPCVATG 345
Query: 359 RPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAY 418
+P P + W NG Y +G L L +V + + QC A N +G + ANA
Sbjct: 346 KPIPTIRWLKNG-----------YAYHKGELRLYDVTFENAGMYQCIAENTYGAIYANAE 394
Query: 419 IYVVQL-PAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTT-VLQDERFFP 476
+ ++ L P + + +A +G + CK AP P W GT ++ R
Sbjct: 395 LKILALAPTFEMNPMKKKILAAKGGRVIIECKPKAAPKPKFSW--SKGTEWLVNSSRILI 452
Query: 477 YANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVT 536
+ +G+L I ++ ND G Y C A N++ L + D T+I P + G T
Sbjct: 453 WEDGSLEINNITRNDGGIYTCFAENNRGKANSTGTLVITDPTRIILAPINADITVGENAT 512
Query: 537 FTCQASFDPSLQPSITWRGDGRDLQELGDSDKY---FIED--GRLVIHSLDYSDQGNYSC 591
C ASFDP+L + W +G + ++ Y F+ D G L+I + G Y+C
Sbjct: 513 MQCAASFDPALDLTFVWSFNGYVIDFNKENIHYQRNFMLDSNGELLIRNAQLKHAGRYTC 572
Query: 592 VASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAEDHNAPIEKYDIE 651
A T +D + A L+V G PGP L + D+ + V ++WS D+++PI KY I+
Sbjct: 573 TAQTIVDNSSASADLVVRGPPGPPGGLRIEDIRA---TSVALTWSRGSDNHSPISKYTIQ 629
Query: 652 FEDKEMAPEKWYSLGKVP----GN-QTSTTLKLSPYVHYTFRVTAINKYGPGEPSPVSET 706
K + + W P GN + + + L P++ Y FRV A N G GEPS S
Sbjct: 630 --TKTILSDDWKDAKTDPPIIEGNMEAARAVDLIPWMEYEFRVVATNTLGRGEPSIPSNR 687
Query: 707 VVTPEAAPEKNPVDVKGEGNETTNMVITWKPLRWMDWNAPQVQYRVQWRPQGTRGPWQEQ 766
+ T AAP P DV G G + ITW PL Y V ++P W++
Sbjct: 688 IKTDGAAPNVAPSDVGGGGGRNRELTITWAPLSREYHYGNNFGYIVAFKPFDGE-EWKKV 746
Query: 767 IVSDPFL--VVSNTSTFVP---YEIKVQAVNSQGKGPEPQVTIGYSGEDYPQAIPELEGI 821
V++P V T P +++KV+A N++G GP V + S +D P P G+
Sbjct: 747 TVTNPDTGRYVHKDETMSPSTAFQVKVKAFNNKGDGPYSLVAVINSAQDAPSEAPTEVGV 806
Query: 822 EILNSSAVLVKWRPVDLAQVKGHLRGYNVTYWREGSQRKHSKRHIHKDHVVVPANTTSVI 881
++L+SS + V W V ++ + Y + YW + + + R V V + S
Sbjct: 807 KVLSSSEISVHWEHV----LEKIVESYQIRYWAAHDKEEAANR------VQVTSQEYSAR 856
Query: 882 LSGLRPYSSYHLEVQAFNGRGSGPASEFTFS-TPEGVPGHPEALHLECQSNTSLLLRWQ- 939
L L P + Y +EV A N G GP S+ + T + P P + +S + ++ W
Sbjct: 857 LENLLPDTQYFIEVGACNSAGCGPPSDMIEAFTKKAPPSQPPRIISSVRSGSRYIITWDH 916
Query: 940 -PPLSHNGVLTGYVLSYHP 957
LS+ +TGY + Y P
Sbjct: 917 VVALSNESTVTGYKVLYRP 935
Score = 41.2 bits (95), Expect = 0.006
Identities = 54/217 (24%), Positives = 84/217 (38%), Gaps = 31/217 (14%)
Query: 625 LLTQSQVRVSWSPAEDHNAPIEKYDIEF---EDKEMAPEKWYSLGKVPGNQTSTTLK-LS 680
+L+ S++ V W + +E Y I + DKE A + +V + S L+ L
Sbjct: 808 VLSSSEISVHWEHVLEKI--VESYQIRYWAAHDKEEAANRV----QVTSQEYSARLENLL 861
Query: 681 PYVHYTFRVTAINKYGPGEPSPVSETVVTPEAAPEKNPVDVKGEGNETTNMVITWKPLRW 740
P Y V A N G G PS + E + AP P + + +ITW +
Sbjct: 862 PDTQYFIEVGACNSAGCGPPSDMIEAFT--KKAPPSQPPRIISSVRSGSRYIITWDHVVA 919
Query: 741 MDWNAPQVQYRVQWRPQGTRGPWQEQIVSDPFLVVSNTSTFVP------YEIKVQAVNSQ 794
+ + Y+V +RP G S VP Y ++V+A +
Sbjct: 920 LSNESTVTGYKVLYRPDGQH--------DGKLYSTHKHSIEVPIPRDGEYVVEVRAHSDG 971
Query: 795 GKGPEPQVTIGYSGEDYPQAIPELEGIEILNSSAVLV 831
G G QV I + P P L G+ +L + +LV
Sbjct: 972 GDGVVSQVKISGA----PTLSPSLLGL-LLPAFGILV 1003
Score = 33.5 bits (75), Expect = 1.3
Identities = 33/140 (23%), Positives = 53/140 (37%), Gaps = 7/140 (5%)
Query: 869 DHVVVPANTTSVILSGLRPYSSYHLEVQAFN--GRGSGPASEFTFSTPEGVPG-HPEALH 925
D ++ N + L P+ Y V A N GRG T P P +
Sbjct: 644 DPPIIEGNMEAARAVDLIPWMEYEFRVVATNTLGRGEPSIPSNRIKTDGAAPNVAPSDVG 703
Query: 926 LECQSNTSLLLRWQPPLS---HNGVLTGYVLSYHPLDEGGKGQLSFNLRDPELRTHNLTD 982
N L + W P LS H G GY++++ P D +++ D H
Sbjct: 704 GGGGRNRELTITWAP-LSREYHYGNNFGYIVAFKPFDGEEWKKVTVTNPDTGRYVHKDET 762
Query: 983 LSPHLRYRFQLQATTKEGPG 1002
+SP ++ +++A +G G
Sbjct: 763 MSPSTAFQVKVKAFNNKGDG 782
>gi|28373126 contactin 4 isoform c precursor [Homo sapiens]
Length = 698
Score = 259 bits (661), Expect = 1e-68
Identities = 183/623 (29%), Positives = 298/623 (47%), Gaps = 38/623 (6%)
Query: 353 DCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGL 412
+C+ GRP+P W NG P+ L +D + +I++G L ++ V SD + QC A N+HG+
Sbjct: 8 ECKANGRPKPTYKWLKNGEPL--LTRD-RIQIEQGTLNITIVNLSDAGMYQCLAENKHGV 64
Query: 413 LLANAYIYVVQL-PAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQD 471
+ +NA + V+ + P T + + G + CK +P P W + G +L++
Sbjct: 65 IFSNAELSVIAVGPDFSRTLLKRVTLVKVGGEVVIECKPKASPKPVYTW--KKGRDILKE 122
Query: 472 -ERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEK 530
ER +G L I ++ +D G Y C+A N + NL VKD T++ P S
Sbjct: 123 NERITISEDGNLRIINVTKSDAGSYTCIATNHFGTASSTGNLVVKDPTRVMVPPSSMDVT 182
Query: 531 KGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGR-----LVIHSLDYSD 585
G + CQ + D SL TW +G + D D + G+ L+I ++
Sbjct: 183 VGESIVLPCQVTHDHSLDIVFTWSFNGHLIDFDRDGDHFERVGGQDSAGDLMIRNIQLKH 242
Query: 586 QGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAEDHNAPI 645
G Y C+ T +D + + A L+V G PGP + + ++ T + ++SW P D+++PI
Sbjct: 243 AGKYVCMVQTSVDRLSAAADLIVRGPPGPPEAVTIDEI---TDTTAQLSWRPGPDNHSPI 299
Query: 646 EKYDIEFEDKEMAPEKWYSLGKVPG-----NQTSTTLKLSPYVHYTFRVTAINKYGPGEP 700
Y I+ W ++ VP T+T + L+P+V Y FR A N G GEP
Sbjct: 300 TMYVIQARTPFSVG--WQAVSTVPELIDGKTFTATVVGLNPWVEYEFRTVAANVIGIGEP 357
Query: 701 SPVSETVVTPEAAPEKNPVDVKGEGNETTNMVITWKPLRWMDWNAPQVQYRVQWRPQGTR 760
S SE T EA PE P +V G G + +VITW+ + N Y V +RP G +
Sbjct: 358 SRPSEKRRTEEALPEVTPANVSGGGGSKSELVITWETVPEELQNGRGFGYVVAFRPYG-K 416
Query: 761 GPWQEQIVSD---PFLVVSNTST--FVPYEIKVQAVNSQGKGPEPQVTIGYSGEDYPQAI 815
W +++ V N S F P+E+KV N++G+GP T+ YS E+ P
Sbjct: 417 MIWMLTVLASADASRYVFRNESVHPFSPFEVKVGVFNNKGEGPFSPTTVVYSAEEEPTKP 476
Query: 816 PELEGIEILNSSAVLVKWRPVDLAQVKGHLRGYNVTYWREGSQRKHSKRHIHKDHVVVPA 875
P L+++ + V W L + +G ++GY V YWR + +++++ +
Sbjct: 477 PASIFARSLSATDIEVFWAS-PLEKNRGRIQGYEVKYWRHEDKEENARK------IRTVG 529
Query: 876 NTTSVILSGLRPYSSYHLEVQAFNGRGSGPAS-EFTFSTPEGVPGHPEALHLECQSNTSL 934
N TS ++ L+ YHL V+A+N G+GP+S +T + P P + S++ +
Sbjct: 530 NQTSTKITNLKGSVLYHLAVKAYNSAGTGPSSATVNVTTRKPPPSQPPGNIIWNSSDSKI 589
Query: 935 LLRWQ--PPLSHNGVLTGYVLSY 955
+L W L + + GY + Y
Sbjct: 590 ILNWDQVKALDNESEVKGYKVLY 612
Score = 77.4 bits (189), Expect = 8e-14
Identities = 86/335 (25%), Positives = 148/335 (44%), Gaps = 65/335 (19%)
Query: 51 DDISLKCEASGKPEVQFRWTRDGVHFKPKEELGVTVYQSPHSGSFTITGNNSNFAQRFQG 110
+++ +C+A+G+P+ ++W ++G ++ + + G+ IT N + A G
Sbjct: 3 ENVFWECKANGRPKPTYKWLKNGEPLLTRDRIQI------EQGTLNITIVNLSDA----G 52
Query: 111 IYRCFASNKLGTAMSH-EIRLMAEGAPKWPKETVKPVE-VEEGESVVLPCNPPPSAEPLR 168
+Y+C A NK G S+ E+ ++A G P + + +K V V+ G VV+ C P S +P+
Sbjct: 53 MYQCLAENKHGVIFSNAELSVIAVG-PDFSRTLLKRVTLVKVGGEVVIECKPKASPKPVY 111
Query: 169 IYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHA--HFPGTRTIIQKEPID 226
+ IL K++ER+T+ ++GNL NV SD S Y C A HF GT
Sbjct: 112 TWKKGRDIL--KENERITISEDGNLRIINVTKSDAGS-YTCIATNHF-GT---------- 157
Query: 227 LRVKATNSMIDRKP-RLLFPTNSSSHLVALQGQPLVLEC-----------IAEGFPTPTI 274
+T +++ + P R++ P +S V G+ +VL C F I
Sbjct: 158 --ASSTGNLVVKDPTRVMVPPSSMDVTV---GESIVLPCQVTHDHSLDIVFTWSFNGHLI 212
Query: 275 KWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPY 334
+ R +RV Q+ L + + + G+Y C+ + S+ A + V P
Sbjct: 213 DFDRDGDHF--ERVGGQDSAGDLMIRNIQLKHAGKYVCMVQTSVDRLSAAADLIVRGPP- 269
Query: 335 WLHKPQSHLYGPGETARLD------CQVQGRPQPE 363
GP E +D Q+ RP P+
Sbjct: 270 ----------GPPEAVTIDEITDTTAQLSWRPGPD 294
Score = 47.0 bits (110), Expect = 1e-04
Identities = 30/116 (25%), Positives = 50/116 (43%), Gaps = 2/116 (1%)
Query: 257 GQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAEN 316
G +V+EC + P P W + + + + + L+++ V + D G Y C+A N
Sbjct: 94 GGEVVIECKPKASPKPVYTWKKGRDILKENERITISEDGNLRIINVTKSDAGSYTCIATN 153
Query: 317 SLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEV--TWRING 370
G+A + V+ + P S GE+ L CQV ++ TW NG
Sbjct: 154 HFGTASSTGNLVVKDPTRVMVPPSSMDVTVGESIVLPCQVTHDHSLDIVFTWSFNG 209
>gi|119220552 sidekick 1 [Homo sapiens]
Length = 2213
Score = 258 bits (660), Expect = 2e-68
Identities = 243/969 (25%), Positives = 402/969 (41%), Gaps = 59/969 (6%)
Query: 55 LKCEASGKPEVQFRWTRDGVHFKPKEELGVTVYQSPHSGSFTITGNNSNFAQRFQGIYRC 114
L C A G ++F+W RD + +T Y S + + + G YRC
Sbjct: 124 LTCLAEGSWPLEFKWMRD--------DSELTTYSSEYKYIIP------SLQKLDAGFYRC 169
Query: 115 FASNKLGTAMSHEIRLMAEGAPKWPKETVKPVEVEEGESVVLPCNPPPSAEPLRIYWMNS 174
N++G + + + + +T + V +G + +L P S ++ W
Sbjct: 170 VVRNRMGALLQRKSEVQVAYMGSF-MDTDQRKTVSQGRAAILNLLPITSYPRPQVTWFRE 228
Query: 175 --KILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEP-IDLRV-K 230
KI+ R+ + L TSD + Y+ + + P I L + +
Sbjct: 229 GHKII---PSNRIAITLENQLVILATTTSDAGAYYVQAVNEKNGEN--KTSPFIHLSIAR 283
Query: 231 ATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTP--TIKWLRPSGPMPADRV 288
+ P ++ P + S V LECIA P ++ W R R+
Sbjct: 284 DVGTPETMAPTIVVPPGNRS--VVAGSSETTLECIASARPVEDLSVTWKRNGV-----RI 336
Query: 289 TYQNHN--KTLQLLKVGEEDDGEYRC---LAENSLGSARHAYYVTVEAAPYWLHKPQSHL 343
T H+ + L + D G Y C L ++ AR ++ + PY+ +P+S +
Sbjct: 337 TSGLHSFGRRLTISNPTSADTGPYVCEAALPGSAFEPARATAFLFIIEPPYFTAEPESRI 396
Query: 344 YGP-GETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVT 402
ET + CQ G P P + W + I + L + + G L + ++P D+ +
Sbjct: 397 SAEVEETVDIGCQAMGVPLPTLQWYKDAISISRLQNPRYKVLASGGLRIQKLRPEDSGIF 456
Query: 403 QCEARNRHGLLLANAYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLD 462
QC A N G + + Y+ V + A + T G TA L C+ GAP P++ W
Sbjct: 457 QCFASNEGGEIQTHTYLDVTNI-APVFTQRPVDTTVTDGMTAILRCEVSGAPKPAITWKR 515
Query: 463 ED---GTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQ 519
E+ + ++ RF +G L I + D G Y C AAN + ++ A L V + T
Sbjct: 516 ENHILASGSVRIPRFMLLESGGLQIAPVFIQDAGNYTCYAANTEGSLNASATLTVWNRTS 575
Query: 520 ITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIH 579
I P + KG+ T C A+ DP + W+ D L S +DG L+I
Sbjct: 576 IVHPPEDHVVIKGTTATLHCGATHDPRVSLRYVWKKDNVALTPSSTSRIVVEKDGSLLIS 635
Query: 580 SLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAE 639
D G+YSC +E A+L V+ P L++S + + V +SW
Sbjct: 636 QTWSGDIGDYSCEIVSEGGNDSRMARLEVIELPHSPQNLLVSPNSSHSHAVV-LSWVRPF 694
Query: 640 DHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLK-LSPYVHYTFRVTAINKYGPG 698
D N+PI Y +E + +P K + L V T T+ L+P Y FRV A+N+ G G
Sbjct: 695 DGNSPILYYIVELSENN-SPWKVH-LSNVGPEMTGVTVSGLTPARTYQFRVCAVNEVGRG 752
Query: 699 EPSPVSETVVTPEAAPEKNPVDVKGEGNETTNMVITWKPLRWMDWNAPQVQYRVQWRPQG 758
+ S + ++ PE P P ++ G ++++ W+P + N Y +++R G
Sbjct: 753 QYSAETSRLMLPEEPPSAPPKNIVASGRTNQSIMVQWQPPPETEHNGVLRGYILRYRLAG 812
Query: 759 TRGPWQEQIVSDP---FLVVSNTSTFVPYEIKVQAVNSQGKGPEPQVTIGYSGEDYPQAI 815
G +Q++ ++ P + +V++ + YEI+V A N G G + Y+ + P A
Sbjct: 813 LPGEYQQRNITSPEVNYCLVTDLIIWTQYEIQVAAYNGAGLGVFSRAVTEYTLQGVPTAP 872
Query: 816 PELEGIEILNSSAVLVKWRPVDLAQVKGHLRGYNVTYWREGSQRKHSKRHIHKD-HVVVP 874
P+ E +NS+ + W P + G +GY + W + + I D H V
Sbjct: 873 PQNVQTEAVNSTTIQFLWNPPPQQFINGINQGYKLLAWPADAPEAVTVVTIAPDFHGVHH 932
Query: 875 ANTTSVILSGLRPYSSYHLEVQAFNGRGSGPASEFTFS-TPEGVPGHPEALHLECQSNTS 933
+ T+ L+ +++Y V F G GP S T E PG L +TS
Sbjct: 933 GHITN-----LKKFTAYFTSVLCFTTPGDGPPSTPQLVWTQEDKPGAVGHLSFTEILDTS 987
Query: 934 LLLRWQPPLSHNGVLTGYVLSYHPLDEGGKGQLSFNLRDPELRTHNLTDLSPHLRYRFQL 993
L + WQ PL NG++TGY +S+ +L+ L + + + LS Y +
Sbjct: 988 LKVSWQEPLEKNGIITGYQISWEVYGR-NDSRLTHTL-NSTTHEYKIQGLSSLTTYTIDV 1045
Query: 994 QATTKEGPG 1002
A T G G
Sbjct: 1046 AAVTAVGTG 1054
Score = 154 bits (389), Expect = 5e-37
Identities = 113/405 (27%), Positives = 185/405 (45%), Gaps = 21/405 (5%)
Query: 612 PGPVPRLVLSDLHLLTQSQVRVSWSPAEDHNAPIEKYDIEFEDKEMAPEK-WYSLGKVPG 670
PG LV+S++ + + + P D I ++ +E + + E+ W +L +
Sbjct: 1070 PGAPSNLVISNI---SPRSATLQFRPGYDGKTSISRWIVEGQVGAIGDEEEWVTLYEEEN 1126
Query: 671 NQTSTTLK---LSPYVHYTFRVTAINKYGPGEPSPVSETVVTPEAAPEKNPVDVKGEGNE 727
+ L+ L+PY HY FR+ +N GP SP S + T +A P+ P V
Sbjct: 1127 EPDAQMLEIPNLTPYTHYRFRMKQVNIVGPSPYSPSSRVIQTLQAPPDVAPTSVTVRTAS 1186
Query: 728 TTNMVITWKPLRWMDWNA--PQVQYRVQWRPQGTRGPWQEQIVSDPF---LVVSNTSTFV 782
T++ + W PL +N V YR+++ + Q+VSD + ++
Sbjct: 1187 ETSLRLRWVPLPDSQYNGNPESVGYRIKYWRSDLQSSAVAQVVSDRLEREFTIEELEEWM 1246
Query: 783 PYEIKVQAVNSQGKGPEPQVTIGYSGEDYPQAIPELEGIEILNSSAVLVKWRPVDLAQVK 842
YE+++QA N+ G GP +V G + E P A PE E ++S+ +L+ W V
Sbjct: 1247 EYELQMQAFNAVGAGPWSEVVRGRTRESVPSAAPENVSAEAVSSTQILLTWTSVPEQDQN 1306
Query: 843 GHLRGYNVTYWREGSQRKHSKRHIHKDHVVVPANTTSVILSGLRPYSSYHLEVQAFNGRG 902
G + GY + + R + H+V +T S +L+GLR + Y L+V AF G
Sbjct: 1307 GLILGYKILF------RAKDLDPEPRSHIVRGNHTQSALLAGLRKFVLYELQVLAFTRIG 1360
Query: 903 SG-PASEFTFS-TPEGVPGHPEALHLECQSNTSLLLRWQPPLSHNGVLTGYVLSYHPLDE 960
+G P++ T + PG P L TS+ + WQPP NG++ GY ++Y L
Sbjct: 1361 NGVPSTPLILERTKDDAPGPPVRLVFPEVRLTSVRIVWQPPEEPNGIILGYQIAYR-LAS 1419
Query: 961 GGKGQLSFNLRDPELRTHNLTDLSPHLRYRFQLQATTKEGPGEAI 1005
+ +R TDL+P Y F+L A T++G GE +
Sbjct: 1420 SSPHTFTTVEVGATVRQFTATDLAPESAYIFRLSAKTRQGWGEPL 1464
Score = 146 bits (368), Expect = 1e-34
Identities = 223/1033 (21%), Positives = 392/1033 (37%), Gaps = 112/1033 (10%)
Query: 63 PEVQFRWTRDGVHFKPKEELGVTVYQSPHSGSFTITGNNSNFAQRF--QGIYRCFASNKL 120
P Q W R+G P + +T+ I ++ A + Q + NK
Sbjct: 219 PRPQVTWFREGHKIIPSNRIAITL-----ENQLVILATTTSDAGAYYVQAVNEKNGENKT 273
Query: 121 GTAMSHEIRLMAEGAPKWPKETV------KPVEVEEGESVVLPCNPPPSAEPLRIYWMNS 174
+ I G P+ T+ + V E+ + E L + W +
Sbjct: 274 SPFIHLSIARDV-GTPETMAPTIVVPPGNRSVVAGSSETTLECIASARPVEDLSVTWKRN 332
Query: 175 KILHIKQDERVTMGQNG---NLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLRVKA 231
+ R+T G + L +N ++D Y+C A PG+ EP +A
Sbjct: 333 GV-------RITSGLHSFGRRLTISNPTSADT-GPYVCEAALPGSAF----EP----ARA 376
Query: 232 TNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQ 291
T + +P F S + A + + + C A G P PT++W + + + R+
Sbjct: 377 TAFLFIIEPPY-FTAEPESRISAEVEETVDIGCQAMGVPLPTLQWYKDA--ISISRLQNP 433
Query: 292 NHNKT----LQLLKVGEEDDGEYRCLAENSLGSAR-HAYYVTVEAAPYWLHKPQSHLYGP 346
+ L++ K+ ED G ++C A N G + H Y AP + +P
Sbjct: 434 RYKVLASGGLRIQKLRPEDSGIFQCFASNEGGEIQTHTYLDVTNIAPVFTQRPVDTTVTD 493
Query: 347 GETARLDCQVQGRPQPEVTW-RINGIPVEELAKDQKYRI-QRGALILSNVQPSDTMVTQC 404
G TA L C+V G P+P +TW R N I + ++ + + G L ++ V D C
Sbjct: 494 GMTAILRCEVSGAPKPAITWKRENHILASGSVRIPRFMLLESGGLQIAPVFIQDAGNYTC 553
Query: 405 EARNRHGLLLANAYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWL--- 461
A N G L A+A + V + + ++ ++ ++G+TA L C A P S++++
Sbjct: 554 YAANTEGSLNASATLTVWNRTSIVHPPED--HVVIKGTTATLHCGATHDPRVSLRYVWKK 611
Query: 462 DEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQIT 521
D T R +G+L I + D G Y C ++ N + MA L+V ++
Sbjct: 612 DNVALTPSSTSRIVVEKDGSLLISQTWSGDIGDYSCEIVSEGGNDSRMARLEV---IELP 668
Query: 522 QGPRSTIEKKGSR----VTFTCQASFD---PSL-------QPSITWR----GDGRDLQEL 563
P++ + S V + FD P L + + W+ G ++ +
Sbjct: 669 HSPQNLLVSPNSSHSHAVVLSWVRPFDGNSPILYYIVELSENNSPWKVHLSNVGPEMTGV 728
Query: 564 GDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDL 623
S + + +++ +G YS E+ +L P P+ +++
Sbjct: 729 TVSGLTPARTYQFRVCAVNEVGRGQYSA---------ETSRLMLPEEPPSAPPKNIVASG 779
Query: 624 HLLTQSQVRVSWSPAED--HNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSP 681
T + V W P + HN + Y + + + E P L
Sbjct: 780 R--TNQSIMVQWQPPPETEHNGVLRGYILRYRLAGLPGEYQQRNITSPEVNYCLVTDLII 837
Query: 682 YVHYTFRVTAINKYGPGEPSPVSETVVTPEAAPEKNPVDVKGEGNETTNMVITWKPLRWM 741
+ Y +V A N G G S + T T + P P +V+ E +T + W P
Sbjct: 838 WTQYEIQVAAYNGAGLGVFSR-AVTEYTLQGVPTAPPQNVQTEAVNSTTIQFLWNPPPQQ 896
Query: 742 DWNAPQVQYRV-QWRPQGTRGPWQEQIVSDPFLV----VSNTSTFVPYEIKVQAVNSQGK 796
N Y++ W I D V ++N F Y V + G
Sbjct: 897 FINGINQGYKLLAWPADAPEAVTVVTIAPDFHGVHHGHITNLKKFTAYFTSVLCFTTPGD 956
Query: 797 GPEPQVTIGYSGEDYPQAIPELEGIEILNSSAVLVKWRPVDLAQVKGHLRGYNVT---YW 853
GP + ++ ED P A+ L EIL++S + V W+ + + G + GY ++ Y
Sbjct: 957 GPPSTPQLVWTQEDKPGAVGHLSFTEILDTS-LKVSWQ--EPLEKNGIITGYQISWEVYG 1013
Query: 854 REGSQRKHSKRHIHKDHVVVPANTTSVILSGLRPYSSYHLEVQAFNGRGSGPASEFTFST 913
R S+ H+ + + T + GL ++Y ++V A G+G + T S+
Sbjct: 1014 RNDSRLTHT----------LNSTTHEYKIQGLSSLTTYTIDVAAVTAVGTGLVTSSTISS 1063
Query: 914 --PEGVPGHPEALHLECQSNTSLLLRWQPPLSHNGVLTGYVLSYHPLDEGGKGQ---LSF 968
P +PG P L + S S L+++P ++ +++ G + + L
Sbjct: 1064 GVPPDLPGAPSNLVISNISPRSATLQFRPGYDGKTSISRWIVEGQVGAIGDEEEWVTLYE 1123
Query: 969 NLRDPELRTHNLTDLSPHLRYRFQLQATTKEGPGEAIVREGGTMALSGISDFGNISA--- 1025
+P+ + + +L+P+ YRF+++ GP L D S
Sbjct: 1124 EENEPDAQMLEIPNLTPYTHYRFRMKQVNIVGPSPYSPSSRVIQTLQAPPDVAPTSVTVR 1183
Query: 1026 TAGENYSVVSWVP 1038
TA E + WVP
Sbjct: 1184 TASETSLRLRWVP 1196
Score = 132 bits (332), Expect = 2e-30
Identities = 133/576 (23%), Positives = 237/576 (41%), Gaps = 50/576 (8%)
Query: 612 PGPVPRLVLSDLHLLTQSQVRVSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGN 671
P P PR +L +T +R+ W P D +PI + ++ +E+ +W + +
Sbjct: 1477 PAP-PRELLVPQAEVTARSLRLQWVPGSDGASPIRYFTMQV--RELPRGEWQTYSSSISH 1533
Query: 672 QTSTTL--KLSPYVHYTFRVTAINKYGPGEPSPVSETVVTPEAAPEKNPVDVKGEGNETT 729
+ + + +L P+ Y R+ A N G + S +E V T + P + P V + T+
Sbjct: 1534 EATACVVDRLRPFTSYKLRLKATNDIGDSDFSSETEAVTTLQDVPGEPPGSVSATPHTTS 1593
Query: 730 NMVITWKPLRWMDWNAPQVQYRVQWRP------QGTRGPW--------QEQIVSDPFLVV 775
+++I W+P R N YR+ +R GT E F V
Sbjct: 1594 SVLIQWQPPRDESLNGLLQGYRIYYRELEYEAGSGTEAKTLKNPIALHAELTAQSSFKTV 1653
Query: 776 SNTST-----------FVPYEIKVQAVNSQGKGPEPQVTIGYSGEDYPQAIPELEGIEIL 824
+++ST + YE+ + A N G+ P + GE P P+ + L
Sbjct: 1654 NSSSTSTMCELTHLKKYRRYEVIMTAYNIIGESPASAPVEVFVGEAAPAMAPQNVQVTPL 1713
Query: 825 NSSAVLVKWRPVDLAQVKGHLRGYNVTYWREGSQRKHSKRHIHKDHVVVPANTTSVILSG 884
+S + V W P G+++GY + YW SQ + K + + +P V L
Sbjct: 1714 TASQLEVTWDPPPPESQNGNIQGYKIYYWEADSQNETEKMKV----LFLPEPV--VRLKN 1767
Query: 885 LRPYSSYHLEVQAFNGRGSGPASE-FTFSTPEGVPGHPEALHLECQSNTSLLLRWQPPLS 943
L ++ Y + + AFN G GP S+ T + PG P L ++T+L + W P +
Sbjct: 1768 LTSHTKYLVSISAFNAAGDGPKSDPQQGRTHQAAPGAPSFLAFSEITSTTLNVSWGEPAA 1827
Query: 944 HNGVLTGYVLSYHPLD--EGGKGQLSFNLRDPELRTHNLTDLSPHLRYRFQLQA-TTKEG 1000
NG+L GY + Y PL +G ++ +R R + DL+ + Y F++QA T G
Sbjct: 1828 ANGILQGYRVVYEPLAPVQGVSKVVTVEVRGNWQRWLKVRDLTKGVTYFFRVQARTITYG 1887
Query: 1001 PG-EAIVREGGTMALSGISDFGNISATAGENYSVVSWVPKEGQCNFRFHILFKALGEEKG 1059
P +A + G G ++ T + + W + +A ++G
Sbjct: 1888 PELQANITAGPAEGSPGSP--RDVLVTKSASELTLQWTEGHSGDTPTTGYVIEARPSDEG 1945
Query: 1060 GASLSPQYVSYNQSSYTQW--DLQPDTDYEIHL--FKERMFRHQMAVKTNGTGRVRLPPA 1115
+ + + + +SYT L+ YE + E + T + +V P
Sbjct: 1946 LWDMFVKDIPRSATSYTLSLDKLRQGVTYEFRVVAVNEAGYGEPSNPSTAVSAQVEAP-- 2003
Query: 1116 GFATEGWFIGFVSAIILLLLVLLILCFIKRSKGGKY 1151
F E WF+ ++ L++++L++ + + KY
Sbjct: 2004 -FYEEWWFLLVMALSSLIVILLVVFALVLHGQNKKY 2038
Score = 107 bits (267), Expect = 7e-23
Identities = 194/807 (24%), Positives = 302/807 (37%), Gaps = 106/807 (13%)
Query: 244 FPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVG 303
F T + L+G LVL C+AEG KW+R + Y+ +LQ L
Sbjct: 106 FKTEPGLPQIHLEGNRLVLTCLAEGSWPLEFKWMRDDSELTTYSSEYKYIIPSLQKL--- 162
Query: 304 EEDDGEYRCLAENSLGS-ARHAYYVTVEAAPYWLHKPQSHLYGPGETARLD-CQVQGRPQ 361
D G YRC+ N +G+ + V V ++ Q G A L+ + P+
Sbjct: 163 --DAGFYRCVVRNRMGALLQRKSEVQVAYMGSFMDTDQRKTVSQGRAAILNLLPITSYPR 220
Query: 362 PEVTWRING---IPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARN-RHGLLLANA 417
P+VTW G IP +A + L++ SD +A N ++G +
Sbjct: 221 PQVTWFREGHKIIPSNRIAITLE-----NQLVILATTTSDAGAYYVQAVNEKNGENKTSP 275
Query: 418 YIYV----------VQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVP--SVQWLDEDG 465
+I++ P ++ N++ +A T L C A PV SV W +G
Sbjct: 276 FIHLSIARDVGTPETMAPTIVVPPGNRSVVAGSSETT-LECIASARPVEDLSVTW-KRNG 333
Query: 466 TTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAA---NDQNNVTIMANLKVKDATQITQ 522
+ F L I + + DTG Y C AA + A L + + T
Sbjct: 334 VRITSGLHSF---GRRLTISNPTSADTGPYVCEAALPGSAFEPARATAFLFIIEPPYFTA 390
Query: 523 GPRSTIEKK-GSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSL 581
P S I + V CQA P P++ W D + L + + G L I L
Sbjct: 391 EPESRISAEVEETVDIGCQAMGVP--LPTLQWYKDAISISRLQNPRYKVLASGGLRIQKL 448
Query: 582 DYSDQGNYSCVASTELDVVESRAQLLV-----VGSPGPVPRLVLSDLHLLTQSQVRVSWS 636
D G + C AS E +++ L V V + PV V + + + +V +
Sbjct: 449 RPEDSGIFQCFASNEGGEIQTHTYLDVTNIAPVFTQRPVDTTVTDGMTAILRCEVSGAPK 508
Query: 637 PA-----EDH-----NAPIEKYD-IEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHY 685
PA E+H + I ++ +E ++AP + GN T ++
Sbjct: 509 PAITWKRENHILASGSVRIPRFMLLESGGLQIAP----VFIQDAGNYTCYAANTEGSLNA 564
Query: 686 TFRVTAINKYGPGEPSPVSETVVTPEAAPEKNPVDVKGEGNETTNMVITWKPLRWMDWNA 745
+ +T N+ T P ++ V +KG T L +
Sbjct: 565 SATLTVWNR--------------TSIVHPPEDHVVIKG----------TTATLHCGATHD 600
Query: 746 PQVQYRVQWRPQG---TRGPWQEQIV-SDPFLVVSNTSTFVPYEIKVQAVNSQGKGPEPQ 801
P+V R W+ T +V D L++S T + + + V+ G
Sbjct: 601 PRVSLRYVWKKDNVALTPSSTSRIVVEKDGSLLISQTWSGDIGDYSCEIVSEGGNDSRMA 660
Query: 802 VTIGYSGEDYPQAIPELEGIEILNSSAVLVKW-RPVDLAQVKGHLRGYNVTYWREGSQRK 860
PQ + L +S AV++ W RP D + Y+
Sbjct: 661 RLEVIELPHSPQNL--LVSPNSSHSHAVVLSWVRPFD--------GNSPILYYIVELSEN 710
Query: 861 HSKRHIHKDHVVVPANTTSVILSGLRPYSSYHLEVQAFN--GRGSGPASEFTFSTPEGVP 918
+S +H + V T V +SGL P +Y V A N GRG A PE P
Sbjct: 711 NSPWKVHLSN--VGPEMTGVTVSGLTPARTYQFRVCAVNEVGRGQYSAETSRLMLPEEPP 768
Query: 919 -GHPEALHLECQSNTSLLLRWQPP--LSHNGVLTGYVLSYHPLDEGGKGQLSFNLRDPEL 975
P+ + ++N S++++WQPP HNGVL GY+L Y G+ Q N+ PE+
Sbjct: 769 SAPPKNIVASGRTNQSIMVQWQPPPETEHNGVLRGYILRYRLAGLPGEYQ-QRNITSPEV 827
Query: 976 RTHNLTDLSPHLRYRFQLQATTKEGPG 1002
+TDL +Y Q+ A G G
Sbjct: 828 NYCLVTDLIIWTQYEIQVAAYNGAGLG 854
Score = 68.6 bits (166), Expect = 4e-11
Identities = 90/422 (21%), Positives = 157/422 (37%), Gaps = 38/422 (9%)
Query: 15 SPCLLIQIPEEYEGHHVMEPPVITEQSPRRLVVFPTDDISLKCEASGKP--EVQFRWTRD 72
SP + + I + M P ++ R VV + + +L+C AS +P ++ W R+
Sbjct: 274 SPFIHLSIARDVGTPETMAPTIVVPPG-NRSVVAGSSETTLECIASARPVEDLSVTWKRN 332
Query: 73 GVHFKPKEELGVTVYQSPHSGSFTITGNNSNFAQRFQGIYRCFAS---NKLGTAMSHEIR 129
GV + HS +T +N A G Y C A+ + A +
Sbjct: 333 GVR----------ITSGLHSFGRRLTISNPTSAD--TGPYVCEAALPGSAFEPARATAFL 380
Query: 130 LMAEGAPKWPKETVKPVEVEEGESVVLPCNPPPSAEPLRIYWMNSKILHIKQDERVTMGQ 189
+ E P + E + E E+V + C P ++ ++ + Q+ R +
Sbjct: 381 FIIE-PPYFTAEPESRISAEVEETVDIGCQAMGVPLPTLQWYKDAISISRLQNPRYKVLA 439
Query: 190 NGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSS 249
+G L + D+ + C A G T++ +D T
Sbjct: 440 SGGLRIQKLRPEDS-GIFQCFASNEGGEI------------QTHTYLDVTNIAPVFTQRP 486
Query: 250 SHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQN----HNKTLQLLKVGEE 305
G +L C G P P I W R + + + V + LQ+ V +
Sbjct: 487 VDTTVTDGMTAILRCEVSGAPKPAITWKRENHILASGSVRIPRFMLLESGGLQIAPVFIQ 546
Query: 306 DDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEV- 364
D G Y C A N+ GS + +TV +H P+ H+ G TA L C P+ +
Sbjct: 547 DAGNYTCYAANTEGSLNASATLTVWNRTSIVHPPEDHVVIKGTTATLHCGATHDPRVSLR 606
Query: 365 -TWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQ 423
W+ + + + + + + G+L++S D CE + G A + V++
Sbjct: 607 YVWKKDNVALTPSSTSRIVVEKDGSLLISQTWSGDIGDYSCEIVSEGGNDSRMARLEVIE 666
Query: 424 LP 425
LP
Sbjct: 667 LP 668
Score = 57.8 bits (138), Expect = 6e-08
Identities = 73/329 (22%), Positives = 129/329 (39%), Gaps = 39/329 (11%)
Query: 31 VMEPPVITEQSPRRLVVFPTDDISLKCEASGKPEVQFRWTRDGVHFKPKEELGVTVYQSP 90
++EPP T + R+ + + + C+A G P +W +D + L Y+
Sbjct: 382 IIEPPYFTAEPESRISAEVEETVDIGCQAMGVPLPTLQWYKDAISI---SRLQNPRYKVL 438
Query: 91 HSGSFTITGNNSNFAQRFQGIYRCFASNKLGTAMSHEIRLMAEGAPKWPKETVKPVE--V 148
SG I GI++CFASN+ G +H + AP + T +PV+ V
Sbjct: 439 ASGGLRI----QKLRPEDSGIFQCFASNEGGEIQTHTYLDVTNIAPVF---TQRPVDTTV 491
Query: 149 EEGESVVLPCNPPPSAEPLRIYWMNSKILHIKQDERV---TMGQNGNLYFANVLTSDNHS 205
+G + +L C + +P I W + R+ + ++G L A V D
Sbjct: 492 TDGMTAILRCEVSGAPKP-AITWKRENHILASGSVRIPRFMLLESGGLQIAPVFIQD-AG 549
Query: 206 DYICHAHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECI 265
+Y C+A L AT ++ +R + P + V ++G L C
Sbjct: 550 NYTCYA---------ANTEGSLNASATLTVWNRTSIVHPPEDH----VVIKGTTATLHCG 596
Query: 266 AEGFPTPTIK--WLRPS---GPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGS 320
A P +++ W + + P R+ + + +L + + D G+Y C + G+
Sbjct: 597 ATHDPRVSLRYVWKKDNVALTPSSTSRIVVEK-DGSLLISQTWSGDIGDYSCEIVSEGGN 655
Query: 321 ARHAYYVTVEAAPYWLHKPQSHLYGPGET 349
+ V P H PQ+ L P +
Sbjct: 656 DSRMARLEVIELP---HSPQNLLVSPNSS 681
>gi|222352127 sidekick 2 [Homo sapiens]
Length = 2172
Score = 248 bits (632), Expect = 3e-65
Identities = 256/1021 (25%), Positives = 419/1021 (41%), Gaps = 68/1021 (6%)
Query: 8 VWPLLLCSPCLLIQIPEEYEGHHVMEPPVITEQSPRRLVVFPTDDISLKCEASGKPEVQF 67
+W LL+ + L QI V P + R V + + L C A G ++F
Sbjct: 1 MWGLLIWTLLALHQIRAARAQDDVS--PYFKTEPVRTQVHLEGNRLVLTCMAEGSWPLEF 58
Query: 68 RW---TRDGVHFKPKEELGVTVYQSPHSGSFTITGNNSNFAQRFQGIYRCFASNKLGTAM 124
+W R+ F + +T H+G YRC N++G +
Sbjct: 59 KWLHNNRELTKFSLEYRYMITSLDRTHAG-----------------FYRCIVRNRMGALL 101
Query: 125 SHEIRLMAEGAPKWPKETVKPVEVEEGESVVLPCNPPPSAEPLRIYWMNSKILHIKQDER 184
+ + + +E K V GE+ V+ S ++ W I R
Sbjct: 102 QRQTEVQVAYMGSF-EEGEKHQSVSHGEAAVIRAPRIASFPQPQVTWFRDG-RKIPPSSR 159
Query: 185 VTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLRVKATNSMIDR-KPRLL 243
+ + L + + D Y+ A +PI L V+ D P ++
Sbjct: 160 IAITLENTLVILSTVAPDAGRYYV-QAVNDKNGDNKTSQPITLTVENVGGPADPIAPTII 218
Query: 244 FPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWL-RPSGPMPADRVTYQNHNKTLQLLKV 302
P ++S V + LEC+A P + + + G + + ++ +HN+ L +
Sbjct: 219 IPPKNTS--VVAGTSEVTLECVANARPLIKLHIIWKKDGVLLSGGIS--DHNRRLTIPNP 274
Query: 303 GEEDDGEYRC---LAENSLGSARHAYYVTVEAAPYWLHKPQSHLYGPGE-TARLDCQVQG 358
D G Y C L +S+ S Y++V P ++ +P+ H+ E + CQ +G
Sbjct: 275 TGSDAGYYECEAVLRSSSVPSVVRGAYLSVLEPPQFVKEPERHITAEMEKVVDIPCQAKG 334
Query: 359 RPQPEVTWRINGIPVEELAKDQKYRIQR-GALILSNVQPSDTMVTQCEARNRHGLLLANA 417
P P +TW V E+ K ++R + G L +S + P DT + QC ARN G + +
Sbjct: 335 VPPPSITW-YKDAAVVEVEKLTRFRQRNDGGLQISGLVPDDTGMFQCFARNAAGEVQTST 393
Query: 418 YIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVL-----QDE 472
Y+ V + I T + G + L C+ GAP P++ W + G +L Q
Sbjct: 394 YLAVTSIAPNI-TRGPLDSTVIDGMSVVLACETSGAPRPAITW--QKGERILASGSVQLP 450
Query: 473 RFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKG 532
RF P +G+L I +D G Y CLA N + A+L V T+IT+ P+ KG
Sbjct: 451 RFTPLESGSLLISPTHISDAGTYTCLATNSRGVDEASADLVVWARTRITKPPQDQSVIKG 510
Query: 533 SRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSC- 591
++ + C + DP + W DG L +G L I D G Y+C
Sbjct: 511 TQASMVCGVTHDPRVTIRYIWEKDGATLGTESHPRIRLDRNGSLHISQTWSGDIGTYTCR 570
Query: 592 VASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAEDHNAPIEKYDIE 651
V S + +SR+ L V P ++ L + + + ++W+ D N+P+ +Y +E
Sbjct: 571 VISAGGN--DSRSAHLRVRQLPHAPEHPVATLSTVERRAINLTWTKPFDGNSPLIRYILE 628
Query: 652 FEDKEMAPEKW-YSLGKVPGNQTSTTLK-LSPYVHYTFRVTAINKYGPGEPSPVSETVVT 709
+ AP W L V TS T+K L P Y FR+ A+N G G+ S +E V
Sbjct: 629 MSENN-AP--WTVLLASVDPKATSVTVKGLVPARSYQFRLCAVNDVGKGQFSKDTERVSL 685
Query: 710 PEAAPEKNPVDVKGEGNETTNMVITWKPLRWMDWNAPQVQYRVQWRPQGTRGPWQEQIVS 769
PE P P +V G +++I W+P N Y +++ G +Q + ++
Sbjct: 686 PEEPPTAPPQNVIASGRTNQSIMIQWQPPPESHQNGILKGYIIRYCLAGLPVGYQFKNIT 745
Query: 770 DP---FLVVSNTSTFVPYEIKVQAVNSQGKGPEPQVTIGYSGEDYPQAIPELEGIEILNS 826
D L++ + + YEI+V A NS G G ++ + P P E NS
Sbjct: 746 DADVNNLLLEDLIIWTNYEIEVAAYNSAGLGVYSSKVTEWTLQGVPTVPPGNVHAEATNS 805
Query: 827 SAVLVKWRPVDLAQVKGHLRGYNVTYW---REGSQRKHSKRHIHKDHVVVPANTTSVILS 883
+ + W + G +GY + W +E + R +D + V +S
Sbjct: 806 TTIRFTWNAPSPQFINGINQGYKLIAWEPEQEEEVTMVTARPNFQDSIHVG------FVS 859
Query: 884 GLRPYSSYHLEVQAFNGRGSGPAS-EFTFSTPEGVPGHPEALHLECQSNTSLLLRWQPPL 942
GL+ ++ Y V F G GP S T E VPG L +TSL + WQ P
Sbjct: 860 GLKKFTEYFTSVLCFTTPGDGPRSTPQLVRTHEDVPGPVGHLSFSEILDTSLKVSWQEPG 919
Query: 943 SHNGVLTGYVLSYHPLDEGGKGQLSFNLRDPELRTHNLTDLSPHLRYRFQLQATTKEGPG 1002
NG+LTGY +S+ + +++ L + L + +T L+ Y ++ A T +G G
Sbjct: 920 EKNGILTGYRISWEEYNRTNT-RVTHYLPNVTLE-YRVTGLTALTTYTIEVAAMTSKGQG 977
Query: 1003 E 1003
+
Sbjct: 978 Q 978
Score = 150 bits (378), Expect = 1e-35
Identities = 161/633 (25%), Positives = 269/633 (42%), Gaps = 70/633 (11%)
Query: 612 PGPVPRLVLSDLHLLTQSQVRVSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGN 671
P P R ++ + +S V +SW P D +P+ Y I+ +E+ +W +
Sbjct: 1400 PQPPSRPMVQQEDVRARS-VLLSWEPGSDGLSPVRYYTIQ--TRELPSGRWALHSASVSH 1456
Query: 672 QTSTTL--KLSPYVHYTFRVTAINKYGPGEPSPVSETVVTPEAAPEKNPVDVKGEGNETT 729
S+ + +L P+ Y FRV A N G E S SE++ T +AAP++ P + + TT
Sbjct: 1457 NASSFIVDRLKPFTSYKFRVKATNDIGDSEFSEESESLTTLQAAPDEAPTILSVTPHTTT 1516
Query: 730 NMVITWKPLRWMDWNAPQVQYRVQWRP---QGTRG-----------PWQE-------QIV 768
+++I W+P N + +R+++R +G RG W E + +
Sbjct: 1517 SVLIRWQPPAEDKINGILLGFRIRYRELLYEGLRGFTLRGINNPGATWAELTSMYSMRNL 1576
Query: 769 SDPFLV---VSNTSTFVPYEIKVQAVNSQGKGPEPQVTIGYSGEDYPQAIPELEGIEILN 825
S P L + N + YEI++ N+ G+GP + GE P A P +
Sbjct: 1577 SRPSLTQYELDNLNKHRRYEIRMSVYNAVGEGPSSPPQEVFVGEAVPTAAPRNVVVHGAT 1636
Query: 826 SSAVLVKWRPVDLAQVKGHLRGYNVTYWREGSQRKHSKRHIHKDHVVVPANTTSVILSGL 885
++ + V W P L G ++GY + +W +QR + + + SV L L
Sbjct: 1637 ATQLDVTWEPPPLDSQNGDIQGYKIYFWE--AQRGNLTERVKTLFLA----ENSVKLKNL 1690
Query: 886 RPYSSYHLEVQAFNGRGSGPASEFT-FSTPEGVPGHPEALHLECQSNTSLLLRWQPPLSH 944
Y++Y + V AFN G GP S T T + P P ++ + TS+ + W+ P
Sbjct: 1691 TGYTAYMVSVAAFNAAGDGPRSTPTQGQTQQAAPSAPSSVKFSELTTTSVNVSWEAPQFP 1750
Query: 945 NGVLTGYVLSYHPLD--EGGKGQLSFNLRDPELRTHNLTDLSPHLRYRFQLQATT-KEGP 1001
NG+L GY L Y P +G ++ +++ + DL+ + YRF+++A T GP
Sbjct: 1751 NGILEGYRLVYEPCSPVDGVSKIVTVDVKGNSPLWLKVKDLAEGVTYRFRIRAKTFTYGP 1810
Query: 1002 G-EAIVREG---GTMALSGISDFGNISATAGENYSVVSWVPKEGQCNFRFHILFKALGEE 1057
EA V G G G+ S+ ++S S P +G + +A +
Sbjct: 1811 EIEANVTTGPGEGAPGPPGVPIIVRYSSAIAIHWS--SGDPGKGPIT---RYVIEARPSD 1865
Query: 1058 KGGASLSPQYVSYNQSSYT-QWD-LQPDTDYEIHLFKERMFRHQMAVKTNGTGRVRLP-- 1113
+G + + + SSYT D L+P Y+ + +AV G G P
Sbjct: 1866 EGLWDILIKDIPKEVSSYTFSMDILKPGVSYDFRV---------IAVNDYGFGTPSSPSQ 1916
Query: 1114 --PA----GFATEGWFIGFVSAIILLLLVLLILCFIKRSKGGKYSVKDKEDTQVDSEA-- 1165
PA F E WF+ ++ + L+ ++LL+ I R + KY+ K S A
Sbjct: 1917 SVPAQKANPFYEEWWFLVVIALVGLIFILLLVFVLIIRGQSKKYAKKTDSGNSAKSGALG 1976
Query: 1166 -RPMKDETFGEYRSLESDNEEKAFGSSQPSLNG 1197
M + +LE +N + +S NG
Sbjct: 1977 HSEMMSLDESSFPALELNNRRLSVKNSFCRKNG 2009
Score = 146 bits (369), Expect = 1e-34
Identities = 250/1093 (22%), Positives = 416/1093 (38%), Gaps = 123/1093 (11%)
Query: 63 PEVQFRWTRDGVHFKPKEELGVTVYQSPHSGSFTITGNNSNFAQRFQGIYRCFASNKLG- 121
P+ Q W RDG P + +T+ + I + A R+ Y ++K G
Sbjct: 141 PQPQVTWFRDGRKIPPSSRIAITL-----ENTLVILSTVAPDAGRY---YVQAVNDKNGD 192
Query: 122 TAMSHEIRLMAE--GAPKWPKETV-----KPVEVEEGES-VVLPC--NPPPSAEPLRIYW 171
S I L E G P P K V G S V L C N P + L I W
Sbjct: 193 NKTSQPITLTVENVGGPADPIAPTIIIPPKNTSVVAGTSEVTLECVANARPLIK-LHIIW 251
Query: 172 MNSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPIDLRVKA 231
+L N L N SD Y C A +++ + V+
Sbjct: 252 KKDGVLL----SGGISDHNRRLTIPNPTGSDA-GYYECEA-------VLRSSSVPSVVRG 299
Query: 232 TNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTY- 290
+ P+ F H+ A + + + C A+G P P+I W + + + +++T
Sbjct: 300 AYLSVLEPPQ--FVKEPERHITAEMEKVVDIPCQAKGVPPPSITWYKDAAVVEVEKLTRF 357
Query: 291 -QNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEA-APYWLHKPQSHLYGPGE 348
Q ++ LQ+ + +D G ++C A N+ G + + Y+ V + AP P G
Sbjct: 358 RQRNDGGLQISGLVPDDTGMFQCFARNAAGEVQTSTYLAVTSIAPNITRGPLDSTVIDGM 417
Query: 349 TARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYR---IQRGALILSNVQPSDTMVTQCE 405
+ L C+ G P+P +TW+ G + Q R ++ G+L++S SD C
Sbjct: 418 SVVLACETSGAPRPAITWQ-KGERILASGSVQLPRFTPLESGSLLISPTHISDAGTYTCL 476
Query: 406 ARNRHGLLLANAYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWL-DED 464
A N G+ A+A + VV +I T Q ++G+ A ++C P +++++ ++D
Sbjct: 477 ATNSRGVDEASADL-VVWARTRI-TKPPQDQSVIKGTQASMVCGVTHDPRVTIRYIWEKD 534
Query: 465 GTTVLQDE--RFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQ 522
G T+ + R NG+L I + D G Y C + N + A+L+V+ +
Sbjct: 535 GATLGTESHPRIRLDRNGSLHISQTWSGDIGTYTCRVISAGGNDSRSAHLRVRQLPHAPE 594
Query: 523 GP---RSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRD-----LQELGDSDKYFIEDG 574
P ST+E++ +T+T + L I + L + G
Sbjct: 595 HPVATLSTVERRAINLTWTKPFDGNSPLIRYILEMSENNAPWTVLLASVDPKATSVTVKG 654
Query: 575 RLVIHSLDY-----SDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQS 629
+ S + +D G TE R L P ++ S T
Sbjct: 655 LVPARSYQFRLCAVNDVGKGQFSKDTE------RVSLPEEPPTAPPQNVIASGR---TNQ 705
Query: 630 QVRVSWSPA-EDH-NAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTL--KLSPYVHY 685
+ + W P E H N ++ Y I + + Y + + L L + +Y
Sbjct: 706 SIMIQWQPPPESHQNGILKGYIIRYCLAGLPVG--YQFKNITDADVNNLLLEDLIIWTNY 763
Query: 686 TFRVTAINKYGPGEPSPVSETVVTPEAAPEKNPVDVKGEGNETTNMVITWKPLRWMDWNA 745
V A N G G S T T + P P +V E +T + TW NA
Sbjct: 764 EIEVAAYNSAGLGVYSS-KVTEWTLQGVPTVPPGNVHAEATNSTTIRFTW--------NA 814
Query: 746 PQVQY---------RVQWRPQG-------TRGPWQEQIVSDPFLVVSNTSTFVPYEIKVQ 789
P Q+ + W P+ T P + + F VS F Y V
Sbjct: 815 PSPQFINGINQGYKLIAWEPEQEEEVTMVTARPNFQDSIHVGF--VSGLKKFTEYFTSVL 872
Query: 790 AVNSQGKGPEPQVTIGYSGEDYPQAIPELEGIEILNSSAVLVKWRPVDLAQVKGHLRGYN 849
+ G GP + + ED P + L EIL++S + V W+ + + G L GY
Sbjct: 873 CFTTPGDGPRSTPQLVRTHEDVPGPVGHLSFSEILDTS-LKVSWQ--EPGEKNGILTGYR 929
Query: 850 VTYWREGSQRKHSKRHIHKDHVVVPANTTSVILSGLRPYSSYHLEVQAFNGRGSGPASEF 909
++ W E ++ H +P T ++GL ++Y +EV A +G G S
Sbjct: 930 IS-WEEYNRTNTRVTHY------LPNVTLEYRVTGLTALTTYTIEVAAMTSKGQGQVSAS 982
Query: 910 TFST--PEGVPGHPEALHLECQSNTSLLLRWQPPLSHNGVLTGYVLSYH--PLDEGGKGQ 965
T S+ P +PG P L + S+ L+++P ++ +++ + EG +
Sbjct: 983 TISSGVPPELPGPPTNLGISNIGPRSVTLQFRPGYDGKTSISRWLVEAQVGVVGEGEEWL 1042
Query: 966 LSFNL-RDPELRTHNLTDLSPHLRYRFQLQATTKEGPGEAIVREGGTMALSGISDF--GN 1022
L L +P+ R+ + DL+P Y F+++ G L D N
Sbjct: 1043 LIHQLSNEPDARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQPSRKIQTLQAPPDMAPAN 1102
Query: 1023 IS-ATAGENYSVVSWVP-KEGQCNFRFHIL---FKALGEEKGGASLSPQYVSYNQSSYTQ 1077
+S TA E + W+P E + N + K + G +LS + YT
Sbjct: 1103 VSLRTASETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDRVERDYTI 1162
Query: 1078 WDLQPDTDYEIHL 1090
DL+ T+Y + +
Sbjct: 1163 EDLEEWTEYRVQV 1175
Score = 145 bits (367), Expect = 2e-34
Identities = 127/495 (25%), Positives = 213/495 (43%), Gaps = 27/495 (5%)
Query: 612 PGPVPRLVLSDLHLLTQSQVRVSWSPAEDHNAPIEKYDIEFEDKEMAP-EKW---YSLGK 667
PGP L +S++ V + + P D I ++ +E + + E+W + L
Sbjct: 993 PGPPTNLGISNIG---PRSVTLQFRPGYDGKTSISRWLVEAQVGVVGEGEEWLLIHQLSN 1049
Query: 668 VPGNQTSTTLKLSPYVHYTFRVTAINKYGPGEPSPVSETVVTPEAAPEKNPVDVKGEGNE 727
P ++ L+P+ Y+FR+ +N G PS S + T +A P+ P +V
Sbjct: 1050 EPDARSMEVPDLNPFTCYSFRMRQVNIVGTSPPSQPSRKIQTLQAPPDMAPANVSLRTAS 1109
Query: 728 TTNMVITWKPLRWMDWNA--PQVQYRVQWRPQGTRGPWQEQIVSDPF---LVVSNTSTFV 782
T++ + W PL M++N V Y++++ G +V D + + +
Sbjct: 1110 ETSLWLRWMPLPEMEYNGNPESVGYKIKYSRSDGHGKTLSHVVQDRVERDYTIEDLEEWT 1169
Query: 783 PYEIKVQAVNSQGKGPEPQVTIGYSGEDYPQAIPELEGIEILNSSAVLVKWRPVDLAQVK 842
Y ++VQA N+ G GP Q +G + E P + P SS++LV+W V A
Sbjct: 1170 EYRVQVQAFNAIGSGPWSQTVVGRTRESVPSSGPTNVSALATTSSSMLVRWSEVPEADRN 1229
Query: 843 GHLRGYNVTYWREGSQRKHSKRHIHKDHVVVPANTTSVILSGLRPYSSYHLEVQAFNGRG 902
G + GY V Y + S + + +V ++ S L+GL Y Y ++V AF G
Sbjct: 1230 GLVLGYKVMYKEKDSDTQ------PRFWLVEGNSSRSAQLTGLGKYVLYEVQVLAFTRIG 1283
Query: 903 SGPASE--FTFSTPEGVPGHPEALHLECQSNTSLLLRWQPPLSHNGVLTGYVLSYHPLDE 960
G S T + VPG P + TS+ L WQPP + NG++ Y ++ H L+
Sbjct: 1284 DGSPSHPPILERTLDDVPGPPMGILFPEVRTTSVRLIWQPPAAPNGIILAYQIT-HRLNT 1342
Query: 961 GGKGQLSFNLRDPELRTHNLTDLSPHLRYRFQLQATTKEGPGEAIVREGGTMALSGISDF 1020
+ + P R + T L P Y F++ A T++G GEA T
Sbjct: 1343 TTANTATVEVLAPSARQYTATGLKPESVYLFRITAQTRKGWGEAAEALVVTTEKRDRPQP 1402
Query: 1021 GNISATAGENYS----VVSWVP-KEGQCNFRFHILFKALGEEKGGASLSPQYVSYNQSSY 1075
+ E+ ++SW P +G R++ + + G +L VS+N SS+
Sbjct: 1403 PSRPMVQQEDVRARSVLLSWEPGSDGLSPVRYYTI-QTRELPSGRWALHSASVSHNASSF 1461
Query: 1076 TQWDLQPDTDYEIHL 1090
L+P T Y+ +
Sbjct: 1462 IVDRLKPFTSYKFRV 1476
>gi|20127422 Down syndrome cell adhesion molecule isoform CHD2-42
precursor [Homo sapiens]
Length = 2012
Score = 243 bits (621), Expect = 6e-64
Identities = 251/1016 (24%), Positives = 429/1016 (42%), Gaps = 88/1016 (8%)
Query: 28 GHHVMEPPVITEQSPRRLVVFPTDDISLKCEASGKPEVQFRWTRDGVHFKPKEELGVTVY 87
G ++ P+ SPR++ +SL C +G + + W R+G P + + +T
Sbjct: 306 GRLYVKQPLKATISPRKVKSSVGSQVSLSCSVTGTEDQELSWYRNGEILNPGKNVRITGI 365
Query: 88 QSPHSGSFTITGNNSNFAQRFQGIYRCFASNKLGTAMSHEIRLMAEGAPKWPKETVKPVE 147
H + + G Y+CF +A + ++ +G PK + V
Sbjct: 366 N--HENLIM-----DHMVKSDGGAYQCFVRKDKLSAQDYVQVVLEDGTPKIISAFSEKV- 417
Query: 148 VEEGESVVLPCNPPPSAEPLRIYWMNSKILHIKQDERVT--MGQNGNLYFANVLTSDNHS 205
V E V L CN + P + ++ + R++ + GN+ ++S
Sbjct: 418 VSPAEPVSLMCNVKGTPLPTITWTLDDDPILKGGSHRISQMITSEGNVVSYLNISSSQVR 477
Query: 206 D---YICHAHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVL 262
D Y C A+ ++ + I++R A+ ++ A+ G+ +
Sbjct: 478 DGGVYRCTAN-NSAGVVLYQARINVRGPAS-------------IRPMKNITAIAGRDTYI 523
Query: 263 ECIAEGFPTPTIKWLRPSGPMPAD--RVTYQNHNKTLQLLKVGEE-DDGEYRC--LAENS 317
C G+P +IKW + S +P + +V ++N N TL+L V +E D+GEY C L +
Sbjct: 524 HCRVIGYPYYSIKWYKNSNLLPFNHRQVAFEN-NGTLKLSDVQKEVDEGEYTCNVLVQPQ 582
Query: 318 LGSARHAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQP-EVTWRINGIPVEEL 376
L +++ + +VTV+ P+ + + + G+ + C V P +TW+ +G P+
Sbjct: 583 LSTSQ-SVHVTVKVPPF-IQPFEFPRFSIGQRVFIPCVVVSGDLPITITWQKDGRPIPGS 640
Query: 377 AKDQKYRIQ-RGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQT 435
I +L +SN+ C ARN + + + +V++P K +
Sbjct: 641 LGVTIDNIDFTSSLRISNLSLMHNGNYTCIARNEAAAVEHQSQL-IVRVPPKFVVQPRDQ 699
Query: 436 YMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDE------RFFPYANGTLGIRDLQA 489
+ G L C A G PVP++ W G V Q + R +NG+L I+ +
Sbjct: 700 D-GIYGKAVILNCSAEGYPVPTIVWKFSKGAGVPQFQPIALNGRIQVLSNGSLLIKHVVE 758
Query: 490 NDTGRYFCLAANDQN-NVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQ 548
D+G Y C +ND +V+ L VK IT P +T+ +G + +C A + +
Sbjct: 759 EDSGYYLCKVSNDVGADVSKSMYLTVKIPAMITSYPNTTLATQGQKKEMSCTAHGEKPI- 817
Query: 549 PSITWRGDGRDLQELGDSDKYFI---EDGRLVIHSLDY-----SDQGNYSCVASTELDVV 600
+ W + R + + +Y + E G VI +L D G +SC A
Sbjct: 818 -IVRWEKEDRIINP--EMARYLVSTKEVGEEVISTLQILPTVREDSGFFSCHAINSYGED 874
Query: 601 ESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAEDHNAPIEKYDIEFEDKEMAPE 660
QL V P P P + + D+ T + + W+ D N+PI YDIE ++K +
Sbjct: 875 RGIIQLTVQEPPDP-PEIEIKDVKART---ITLRWTMGFDGNSPITGYDIECKNKS---D 927
Query: 661 KWYSLGKV----PGNQTSTTLKLSPYVHYTFRVTAINKYGPGEPSPVSETVVTPEAAPEK 716
W S + P ++T + + P Y+ R+ A N+ G EPS T+ EAAP+
Sbjct: 928 SWDSAQRTKDVSPQLNSATIIDIHPSSTYSIRMYAKNRIGKSEPSN-ELTITADEAAPDG 986
Query: 717 NPVDVKGEGNETTNMVITWKPLRWMDWNAPQVQYRVQWRPQGTRGPWQEQIVS------D 770
P +V E + ++ +TWK + N Y++ +R T G +Q I+S
Sbjct: 987 PPQEVHLEPISSQSIRVTWKAPKKHLQNGIIRGYQIGYREYSTGGNFQFNIISVDTSGDS 1046
Query: 771 PFLVVSNTSTFVPYEIKVQAVNSQGKGPEPQVTIGYSGEDYPQAIPELEGIEILNSSAVL 830
+ N + F Y + VQA N G GP Q I + ED P PE + ++
Sbjct: 1047 EVYTLDNLNKFTQYGLVVQACNRAGTGPSSQEIITTTLEDVPSYPPENVQAIATSPESIS 1106
Query: 831 VKWRPVDLAQVKGHLRGYNVTYWREGSQRKHSKRHIHKDHVVVPANTTSVILSGLRPYSS 890
+ W + + G L+G+ V YW + + + S+ L GL Y++
Sbjct: 1107 ISWSTLSKEALNGILQGFRVIYWANLMDGELG------EIKNITTTQPSLELDGLEKYTN 1160
Query: 891 YHLEVQAFNGRGSGPASEFTFS-TPEGVPGHPEALHLECQSNTSLLLRWQPPLSHNGVLT 949
Y ++V AF G G SE F+ T E VPG P + S + + + W PPL NG++
Sbjct: 1161 YSIQVLAFTRAGDGVRSEQIFTRTKEDVPGPPAGVKAAAASASMVFVSWLPPLKLNGIIR 1220
Query: 950 GY-VLSYHPLDEGGKGQLSFNLRDPELRTHNLTDLSPHLRYRFQLQATTKEGPGEA 1004
Y V HP +S P+ ++ + +LS + +Y + A T G G +
Sbjct: 1221 KYTVFCSHPYPT----VISEFEASPDSFSYRIPNLSRNRQYSVWVVAVTSAGRGNS 1272
Score = 174 bits (442), Expect = 4e-43
Identities = 255/1039 (24%), Positives = 418/1039 (40%), Gaps = 122/1039 (11%)
Query: 53 ISLKCEASGKPEVQFRWTRDGVHFKPKEELGVTVYQSPHSGSF--TITG-NNSNFAQRFQ 109
+ L C+A G PE +RW +D + + SG F T+TG N
Sbjct: 242 VELPCKALGHPEPDYRWLKDNMPLE-------------LSGRFQKTVTGLLIENIRPSDS 288
Query: 110 GIYRCFASNKLGTAMSHEIRLMAEGAPKWP-KETVKPVEVEE--GESVVLPCNPPPSAEP 166
G Y C SN+ GTA +++ K P K T+ P +V+ G V L C+ + +
Sbjct: 289 GSYVCEVSNRYGTA-----KVIGRLYVKQPLKATISPRKVKSSVGSQVSLSCSVTGTEDQ 343
Query: 167 LRIYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKEPID 226
++ N +IL+ ++ R+T + NL +++ SD + Y C ++K+ +
Sbjct: 344 ELSWYRNGEILNPGKNVRITGINHENLIMDHMVKSDGGA-YQC---------FVRKDKLS 393
Query: 227 LRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPM--- 283
+ + D P+++ ++ S V +P+ L C +G P PTI W P+
Sbjct: 394 AQDYVQVVLEDGTPKII---SAFSEKVVSPAEPVSLMCNVKGTPLPTITWTLDDDPILKG 450
Query: 284 PADRVTYQ--NHNKTLQLLKVGE---EDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHK 338
+ R++ + + L + D G YRC A NS G + + V P +
Sbjct: 451 GSHRISQMITSEGNVVSYLNISSSQVRDGGVYRCTANNSAGVVLYQARINVR-GPASIRP 509
Query: 339 PQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPS- 397
++ G + C+V G P + W N + + + G L LS+VQ
Sbjct: 510 MKNITAIAGRDTYIHCRVIGYPYYSIKWYKNSNLLPFNHRQVAFE-NNGTLKLSDVQKEV 568
Query: 398 DTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPS 457
D C + L + + V++P I + + G ++ C +P
Sbjct: 569 DEGEYTCNVLVQPQLSTSQSVHVTVKVPPFIQPFEFPRFSI--GQRVFIPCVVVSGDLPI 626
Query: 458 VQWLDEDGTT------VLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMAN 511
+DG V D F +L I +L G Y C+A N+ V +
Sbjct: 627 TITWQKDGRPIPGSLGVTIDNIDF---TSSLRISNLSLMHNGNYTCIARNEAAAVEHQSQ 683
Query: 512 LKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITW---RGDG-RDLQELGDSD 567
L V+ + PR G V C A P P+I W +G G Q + +
Sbjct: 684 LIVRVPPKFVVQPRDQDGIYGKAVILNCSAEGYP--VPTIVWKFSKGAGVPQFQPIALNG 741
Query: 568 K-YFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLS--DLH 624
+ + +G L+I + D G Y C S ++ S++ L V +P ++ S +
Sbjct: 742 RIQVLSNGSLLIKHVVEEDSGYYLCKVSNDVGADVSKSMYLTV----KIPAMITSYPNTT 797
Query: 625 LLTQSQVRVSWSPAEDHNAPIEKYDIEFEDKEMAPE--KWYSLGKVPGNQTSTTLKLSPY 682
L TQ Q + A I ++ E ED+ + PE ++ K G + +TL++ P
Sbjct: 798 LATQGQKKEMSCTAHGEKPIIVRW--EKEDRIINPEMARYLVSTKEVGEEVISTLQILPT 855
Query: 683 VHYT---FRVTAINKYGPGEPSPVSETVVTPEAAPEKNPVDVKGEGNETTNMVITWKPLR 739
V F AIN YG + + TV P PE DVK IT +
Sbjct: 856 VREDSGFFSCHAINSYGE-DRGIIQLTVQEPPDPPEIEIKDVKAR-------TITLRWTM 907
Query: 740 WMDWNAPQVQYRVQ-------WRPQGTRGPWQEQIVSDPFLVVSNTSTFVPYEIKVQAVN 792
D N+P Y ++ W Q+ S + + +ST Y I++ A N
Sbjct: 908 GFDGNSPITGYDIECKNKSDSWDSAQRTKDVSPQLNSATIIDIHPSST---YSIRMYAKN 964
Query: 793 SQGKG-PEPQVTIGYSGEDYPQAIPELEGIEILNSSAVLVKWRPVDLAQVKGHLRGYNVT 851
GK P ++TI + E P P+ +E ++S ++ V W+ G +RGY +
Sbjct: 965 RIGKSEPSNELTI-TADEAAPDGPPQEVHLEPISSQSIRVTWKAPKKHLQNGIIRGYQIG 1023
Query: 852 YWREGSQRKHSKRHIHKDHVVVPANTTSVILSGLRPYSSYHLEVQAFNGRGSGPAS-EFT 910
Y RE S + + +I V ++ L L ++ Y L VQA N G+GP+S E
Sbjct: 1024 Y-REYSTGGNFQFNIIS--VDTSGDSEVYTLDNLNKFTQYGLVVQACNRAGTGPSSQEII 1080
Query: 911 FSTPEGVPGH-PEALHLECQSNTSLLLRWQPPLSH--NGVLTGY-VLSYHPLDEGGKGQL 966
+T E VP + PE + S S+ + W NG+L G+ V+ + L +G G++
Sbjct: 1081 TTTLEDVPSYPPENVQAIATSPESISISWSTLSKEALNGILQGFRVIYWANLMDGELGEI 1140
Query: 967 -SFNLRDPELRTHNLTDLSPHLRYRFQLQATTKEGPG---EAI---VREGGTMALSGISD 1019
+ P L L L + Y Q+ A T+ G G E I +E +G+
Sbjct: 1141 KNITTTQPSL---ELDGLEKYTNYSIQVLAFTRAGDGVRSEQIFTRTKEDVPGPPAGVK- 1196
Query: 1020 FGNISATAGENYSVVSWVP 1038
+A A + VSW+P
Sbjct: 1197 ----AAAASASMVFVSWLP 1211
Score = 99.4 bits (246), Expect = 2e-20
Identities = 138/594 (23%), Positives = 215/594 (36%), Gaps = 49/594 (8%)
Query: 41 SPRRLVVFPTDDISLKCEASGKPEVQFRW---TRDGV-------HFKPKEELGVTVYQSP 90
S + +V T + C A+G P V RW T + + H P L ++ P
Sbjct: 30 SLQEVVFASTTGTLVPCPAAGIPPVTLRWYLATGEEIYDVPGIRHVHPNGTL--QIFPFP 87
Query: 91 HSGSFTITGNNSNFAQRFQGIYRCFASNKLGTAMSHEIRLMAEGAPKWPKETVKPVEVEE 150
S T+ +N+ Y C A N G S ++ + A + V+ +
Sbjct: 88 PSSFSTLIHDNT---------YYCTAENPSGKIRSQDVHIKAVLREPYTVR-VEDQKTMR 137
Query: 151 GESVVLPCNPPPSAEP-LRIYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYIC 209
G V C P S E + + + + R + G LY +V D +Y C
Sbjct: 138 GNVAVFKCIIPSSVEAYITVVSWEKDTVSLVSGSRFLITSTGALYIKDVQNEDGLYNYRC 197
Query: 210 HAHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGF 269
T Q L V + + P +L + H A+ GQ + L C A G
Sbjct: 198 ITRHRYTGETRQSNSARLFV---SDPANSAPSIL---DGFDHRKAMAGQRVELPCKALGH 251
Query: 270 PTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTV 329
P P +WL+ + P+ +Q L + + D G Y C N G+A+ + V
Sbjct: 252 PEPDYRWLKDNMPLELSG-RFQKTVTGLLIENIRPSDSGSYVCEVSNRYGTAKVIGRLYV 310
Query: 330 EAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGAL 389
+ P+ G L C V G E++W NG + + I L
Sbjct: 311 KQPLKATISPRKVKSSVGSQVSLSCSVTGTEDQELSWYRNGEILNPGKNVRITGINHENL 370
Query: 390 ILSNVQPSDTMVTQCEARNRHGLLLANAYIYVV--QLPAKILTADNQTYMAVQGSTAYLL 447
I+ ++ SD QC R L A Y+ VV KI++A ++ ++ L+
Sbjct: 371 IMDHMVKSDGGAYQCFVRK--DKLSAQDYVQVVLEDGTPKIISAFSEKVVS-PAEPVSLM 427
Query: 448 CKAFGAPVPSVQW-LDEDGTTVLQDERFFPYANGT------LGIRDLQANDTGRYFCLAA 500
C G P+P++ W LD+D R L I Q D G Y C A
Sbjct: 428 CNVKGTPLPTITWTLDDDPILKGGSHRISQMITSEGNVVSYLNISSSQVRDGGVYRCTAN 487
Query: 501 NDQNNVTIMANLKVKDATQITQGPRSTIEKKGSRVTFT-CQASFDPSLQPSITWRGDGRD 559
N V A + V+ I P I R T+ C+ P SI W + +
Sbjct: 488 NSAGVVLYQARINVRGPASIR--PMKNITAIAGRDTYIHCRVIGYPYY--SIKWYKNS-N 542
Query: 560 LQELGDSDKYFIEDGRLVIHSLDYS-DQGNYSCVASTELDVVESRAQLLVVGSP 612
L F +G L + + D+G Y+C + + S++ + V P
Sbjct: 543 LLPFNHRQVAFENNGTLKLSDVQKEVDEGEYTCNVLVQPQLSTSQSVHVTVKVP 596
Score = 80.1 bits (196), Expect = 1e-14
Identities = 98/399 (24%), Positives = 157/399 (39%), Gaps = 33/399 (8%)
Query: 237 DRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPAD--RVTYQNHN 294
D L F S +V ++ C A G P T++W +G D + + + N
Sbjct: 19 DLHSSLYFVNASLQEVVFASTTGTLVPCPAAGIPPVTLRWYLATGEEIYDVPGIRHVHPN 78
Query: 295 KTLQLLKVGEED------DGEYRCLAENSLGSARH--AYYVTVEAAPYWLHKPQSHLYGP 346
TLQ+ D Y C AEN G R + V PY + + +
Sbjct: 79 GTLQIFPFPPSSFSTLIHDNTYYCTAENPSGKIRSQDVHIKAVLREPYTV-RVEDQKTMR 137
Query: 347 GETARLDCQVQGRPQPEVT---WRINGIPVEELAKDQKYRI-QRGALILSNVQPSDTMVT 402
G A C + + +T W + + L ++ I GAL + +VQ D +
Sbjct: 138 GNVAVFKCIIPSSVEAYITVVSWEKDTV---SLVSGSRFLITSTGALYIKDVQNEDGLYN 194
Query: 403 -QCEARNRHG--LLLANAYIYVVQLPAKILTA-----DNQTYMAVQGSTAYLLCKAFGAP 454
+C R+R+ +N+ V PA + D++ MA G L CKA G P
Sbjct: 195 YRCITRHRYTGETRQSNSARLFVSDPANSAPSILDGFDHRKAMA--GQRVELPCKALGHP 252
Query: 455 VPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKV 514
P +WL +D + RF G L I +++ +D+G Y C +N ++ L V
Sbjct: 253 EPDYRWL-KDNMPLELSGRFQKTVTGLL-IENIRPSDSGSYVCEVSNRYGTAKVIGRLYV 310
Query: 515 KDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG 574
K + T PR GS+V+ +C S + ++W +G L + I
Sbjct: 311 KQPLKATISPRKVKSSVGSQVSLSC--SVTGTEDQELSWYRNGEILNPGKNVRITGINHE 368
Query: 575 RLVIHSLDYSDQGNYSC-VASTELDVVESRAQLLVVGSP 612
L++ + SD G Y C V +L + +L G+P
Sbjct: 369 NLIMDHMVKSDGGAYQCFVRKDKLSAQDYVQVVLEDGTP 407
Score = 76.6 bits (187), Expect = 1e-13
Identities = 69/286 (24%), Positives = 113/286 (39%), Gaps = 16/286 (5%)
Query: 535 VTFTCQASFDPSLQPSITWRGDGRDLQELG--DSDKYFIEDGRLVIHSLDYSDQGNYSCV 592
+ C+A DPS P++ W D L D + +G +I ++ D G YSC+
Sbjct: 1303 IVLPCKAVGDPS--PAVKWMKDSNGTPSLVTIDGRRSIFSNGSFIIRTVKAEDSGYYSCI 1360
Query: 593 ASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAEDHNAPIEKYDIEF 652
A+ E L V P PRL +S T S + +SW P ++ + I Y +++
Sbjct: 1361 ANNNWGSDEIILNLQVQVPPDQ-PRLTVSKT---TSSSITLSWLPGDNGGSSIRGYILQY 1416
Query: 653 EDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAINKYGPGEPSPVSETVVTPEA 712
+ E+W S P ++ L Y F +TA N GPG S + E +
Sbjct: 1417 SEDNS--EQWGSFPISPSERSYRLENLKCGTWYKFTLTAQNGVGPGRISEIIEAKTLGKE 1474
Query: 713 APEKNPVDVKGEGNETTNMVITWKPLRWMDWNAPQVQYRVQWRPQGTRGPWQEQIVS-DP 771
++ N T + + W D P + +++RP GT Q S
Sbjct: 1475 PQFSKEQELFASINTTR---VRLNLIGWNDGGCPITSFTLEYRPFGTTVWTTAQRTSLSK 1531
Query: 772 FLVVSNTSTFVPYEIKVQAVNSQGKGPEPQ--VTIGYSGEDYPQAI 815
++ + YE++++ NS G + T+ Y G P I
Sbjct: 1532 SYILYDLQEATWYELQMRVCNSAGCAEKQANFATLNYDGSTIPPLI 1577
Score = 55.8 bits (133), Expect = 2e-07
Identities = 41/116 (35%), Positives = 61/116 (52%), Gaps = 7/116 (6%)
Query: 421 VVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWL-DEDGTTVLQ--DERFFPY 477
+ + PA+ILT T L CKA G P P+V+W+ D +GT L D R +
Sbjct: 1281 LAKAPARILTFSG-TVTTPWMKDIVLPCKAVGDPSPAVKWMKDSNGTPSLVTIDGRRSIF 1339
Query: 478 ANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEKKGS 533
+NG+ IR ++A D+G Y C+A N+ + I+ NL+V+ PR T+ K S
Sbjct: 1340 SNGSFIIRTVKAEDSGYYSCIANNNWGSDEIILNLQVQVP---PDQPRLTVSKTTS 1392
Score = 43.9 bits (102), Expect = 0.001
Identities = 25/80 (31%), Positives = 40/80 (50%), Gaps = 8/80 (10%)
Query: 260 LVLECIAEGFPTPTIKWLRPSGPMPA------DRVTYQNHNKTLQLLKVGEEDDGEYRCL 313
+VL C A G P+P +KW++ S P+ R + N + ++ +K ED G Y C+
Sbjct: 1303 IVLPCKAVGDPSPAVKWMKDSNGTPSLVTIDGRRSIFSNGSFIIRTVKA--EDSGYYSCI 1360
Query: 314 AENSLGSARHAYYVTVEAAP 333
A N+ GS + V+ P
Sbjct: 1361 ANNNWGSDEIILNLQVQVPP 1380
Score = 40.8 bits (94), Expect = 0.008
Identities = 91/415 (21%), Positives = 149/415 (35%), Gaps = 34/415 (8%)
Query: 679 LSPYVHYTFRVTAINKYGPGEPSPVSETVVTPEAAPEKNPVDVKGEGNETTNMVITWKPL 738
L Y +Y+ +V A + G G S T T E P P VK + + ++W P
Sbjct: 1155 LEKYTNYSIQVLAFTRAGDGVRSEQIFTR-TKEDVPGP-PAGVKAAAASASMVFVSWLPP 1212
Query: 739 RWMDWNAPQVQYRVQWRPQGTRGPWQEQIVSDPFLV-VSNTSTFVPYEIKVQAVNSQGKG 797
+ N +Y V + + D F + N S Y + V AV S G+G
Sbjct: 1213 --LKLNGIIRKYTVFCSHPYPTVISEFEASPDSFSYRIPNLSRNRQYSVWVVAVTSAGRG 1270
Query: 798 PEPQVTIGYSGEDYPQAIPELEGIEILNSSAVLVKWRPVDLAQVKGHLRGYNVTYWREGS 857
++ P I G V W + K W + S
Sbjct: 1271 NSSEIITVEPLAKAPARILTFSG-------TVTTPWMKDIVLPCKAVGDPSPAVKWMKDS 1323
Query: 858 QRKHSKRHIHKDHVVVPANTTSVILSGLRPYSSYHLEVQAFNGRGSGPASEFTFSTPEGV 917
S I + + S I+ ++ S + A N GS E + V
Sbjct: 1324 NGTPSLVTIDGRRSIF--SNGSFIIRTVKAEDSGYYSCIANNNWGS---DEIILNLQVQV 1378
Query: 918 PGHPEALHLECQSNTSLLLRWQPPLSHNGVLTGYVLSYHPLDEGGKGQLSFNLRDPELRT 977
P L + +++S+ L W P + + GY+L Y ++ + SF + P R+
Sbjct: 1379 PPDQPRLTVSKTTSSSITLSWLPGDNGGSSIRGYILQYS--EDNSEQWGSFPI-SPSERS 1435
Query: 978 HNLTDLSPHLRYRFQLQATTKEGPGE-AIVREGGTMALSGISD-----FGNISATAGENY 1031
+ L +L Y+F L A GPG + + E T+ F +I+ T
Sbjct: 1436 YRLENLKCGTWYKFTLTAQNGVGPGRISEIIEAKTLGKEPQFSKEQELFASINTTR-VRL 1494
Query: 1032 SVVSWVPKEGQCNF-RFHILFKALG----EEKGGASLSPQYVSYNQSSYTQWDLQ 1081
+++ W +G C F + ++ G SLS Y+ Y+ T ++LQ
Sbjct: 1495 NLIGW--NDGGCPITSFTLEYRPFGTTVWTTAQRTSLSKSYILYDLQEATWYELQ 1547
Score = 30.8 bits (68), Expect = 8.5
Identities = 18/62 (29%), Positives = 25/62 (40%), Gaps = 2/62 (3%)
Query: 352 LDCQVQGRPQPEVTWR--INGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNR 409
L C+ G P P V W NG P ++ G+ I+ V+ D+ C A N
Sbjct: 1305 LPCKAVGDPSPAVKWMKDSNGTPSLVTIDGRRSIFSNGSFIIRTVKAEDSGYYSCIANNN 1364
Query: 410 HG 411
G
Sbjct: 1365 WG 1366
>gi|110431348 deleted in colorectal carcinoma [Homo sapiens]
Length = 1447
Score = 231 bits (590), Expect = 3e-60
Identities = 208/810 (25%), Positives = 342/810 (42%), Gaps = 74/810 (9%)
Query: 250 SHLVALQGQPLVLECIAEGFP-TPTIKWLRPSGPMPA--DRVTYQNHNKTLQLLKV---- 302
S V ++G ++L+C AE P IKW + + D Q N +L + +
Sbjct: 47 SDAVTMRGGNVLLDCSAESDRGVPVIKWKKDGIHLALGMDERKQQLSNGSLLIQNILHSR 106
Query: 303 -GEEDDGEYRCLAENSLGSARHAYYVTVEAAPY----WLHKPQSHLYGPGETARLDCQVQ 357
+ D+G Y+C E SLG + T + A +L + +S G+T L C+V
Sbjct: 107 HHKPDEGLYQC--EASLGDSGSIISRTAKVAVAGPLRFLSQTESVTAFMGDTVLLKCEVI 164
Query: 358 GRPQPEVTWRINGIPVEELAKDQKYRI-QRGALILSNVQPSDTMVTQCEARNRHGLLLAN 416
G P P + W+ N + + D + + GAL +S +QP D + +C ARN N
Sbjct: 165 GEPMPTIHWQKNQQDLTPIPGDSRVVVLPSGALQISRLQPGDIGIYRCSARNPASSRTGN 224
Query: 417 A-------------YIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDE 463
+Y +Q P+ ++ A++G A L C G P PS WL
Sbjct: 225 EAEVRILSDPGLHRQLYFLQRPSNVV--------AIEGKDAVLECCVSGYPPPSFTWLRG 276
Query: 464 DGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQG 523
+ L+ +++ L I ++ +D+G Y C+ N++ A L V
Sbjct: 277 EEVIQLRSKKYSLLGGSNLLISNVTDDDSGMYTCVVTYKNENISASAELTVLVPPWFLNH 336
Query: 524 PRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDG-RLVIHSLD 582
P + + + F C S P P++ W +G + SD + I G L I +
Sbjct: 337 PSNLYAYESMDIEFECTVSGKPV--PTVNWMKNG---DVVIPSDYFQIVGGSNLRILGVV 391
Query: 583 YSDQGNYSCVASTELDVVESRAQLLV----VGSPGPVPRLVLSDLHLLTQSQ-VRVSWSP 637
SD+G Y CVA E ++ AQL+V + S +P + +L S+ VR+SW P
Sbjct: 392 KSDEGFYQCVAENEAGNAQTSAQLIVPKPAIPSSSVLPSAPRDVVPVLVSSRFVRLSWRP 451
Query: 638 AEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAINKYGP 697
+ I+ + + F + E+ + + PG+ T L P YTFRV A N++GP
Sbjct: 452 PAEAKGNIQTFTVFFSREGDNRERALNTTQ-PGSLQLTVGNLKPEAMYTFRVVAYNEWGP 510
Query: 698 GEPSPVSETVVTPEAAPEKNPVDVKGEGNETTNMVITWKPLRWMDWNAPQVQYRVQWRPQ 757
GE S + PE +++ T+++ITW+P + N P YR+ + +
Sbjct: 511 GESSQPIKVATQPELQVPGPVENLQAVSTSPTSILITWEPPAYA--NGPVQGYRL-FCTE 567
Query: 758 GTRGPWQEQIVSDPFLVVSNTSTFVPYEIKVQAVNSQGKGPEPQVTIGYSGEDYPQAIPE 817
+ G Q V + F Y ++ A N G G + D P A P+
Sbjct: 568 VSTGKEQNIEVDGLSYKLEGLKKFTEYSLRFLAYNRYGPGVSTDDITVVTLSDVPSAPPQ 627
Query: 818 LEGIEILNSSAVLVKWRPVDLAQVKGHLRGYNVTYWREGSQRKHSKRHIHKDHVVVPANT 877
+E++NS ++ V W P G + GY + +H K + + N
Sbjct: 628 NVSLEVVNSRSIKVSWLPPPSGTQNGFITGYKI---------RHRKTTRRGEMETLEPNN 678
Query: 878 TSVILSGLRPYSSYHLEVQAFNGRGSGPASE-FTFSTPEG------VPGHPEALHLECQS 930
+ +GL S Y +V A G+GP S +T TPE VP P +LH+ Q+
Sbjct: 679 LWYLFTGLEKGSQYSFQVSAMTVNGTGPPSNWYTAETPENDLDESQVPDQPSSLHVRPQT 738
Query: 931 NTSLLLRWQPPLSHNGVLTGYVLSYHPLDEGGKGQLSFNLR-DPELRTHNLTDLSPHLRY 989
N +++ W PPL+ N V+ GY++ Y G + +R D + R +++ L Y
Sbjct: 739 N-CIIMSWTPPLNPNIVVRGYIIGY-----GVGSPYAETVRVDSKQRYYSIERLESSSHY 792
Query: 990 RFQLQATTKEGPGEAIVREGGTMALSGISD 1019
L+A G G + T +++ +D
Sbjct: 793 VISLKAFNNAGEGVPLYESATTRSITDPTD 822
Score = 93.6 bits (231), Expect = 1e-18
Identities = 97/388 (25%), Positives = 162/388 (41%), Gaps = 24/388 (6%)
Query: 42 PRRLVVFPTDDISLKCEASGKPEVQ-FRWTRDGVHFKPKEELGVTVYQSPHSGSFTITGN 100
P V ++ L C A V +W +DG+H LG+ + S + N
Sbjct: 46 PSDAVTMRGGNVLLDCSAESDRGVPVIKWKKDGIHLA----LGMDERKQQLSNGSLLIQN 101
Query: 101 --NSNFAQRFQGIYRCFAS-NKLGTAMSHEIRLMAEGAPKWPKETVKPVEVEEGESVVLP 157
+S + +G+Y+C AS G+ +S ++ G ++ +T + V G++V+L
Sbjct: 102 ILHSRHHKPDEGLYQCEASLGDSGSIISRTAKVAVAGPLRFLSQT-ESVTAFMGDTVLLK 160
Query: 158 CNPPPSAEPLRIYWMNSK--ILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAHFPG 215
C P I+W ++ + I D RV + +G L + + D Y C A P
Sbjct: 161 CEVIGEPMPT-IHWQKNQQDLTPIPGDSRVVVLPSGALQISRLQPGDI-GIYRCSARNPA 218
Query: 216 T-RTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTI 274
+ RT + E +R+ + + R L+ S++VA++G+ VLEC G+P P+
Sbjct: 219 SSRTGNEAE---VRILSDPGL----HRQLYFLQRPSNVVAIEGKDAVLECCVSGYPPPSF 271
Query: 275 KWLRPSGPMPADRVTYQ-NHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAP 333
WLR + Y L + V ++D G Y C+ + + +TV P
Sbjct: 272 TWLRGEEVIQLRSKKYSLLGGSNLLISNVTDDDSGMYTCVVTYKNENISASAELTVLVPP 331
Query: 334 YWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSN 393
++L+ P + +C V G+P P V W NG V + D + L +
Sbjct: 332 WFLNHPSNLYAYESMDIEFECTVSGKPVPTVNWMKNGDVV--IPSDYFQIVGGSNLRILG 389
Query: 394 VQPSDTMVTQCEARNRHGLLLANAYIYV 421
V SD QC A N G +A + V
Sbjct: 390 VVKSDEGFYQCVAENEAGNAQTSAQLIV 417
Score = 68.9 bits (167), Expect = 3e-11
Identities = 102/433 (23%), Positives = 168/433 (38%), Gaps = 85/433 (19%)
Query: 623 LHLLTQSQVRVSW--SPAEDHNAPIEKYDIEF-------EDKEMAPEK-WYSL-GKVPGN 671
L ++ ++VSW P+ N I Y I E + + P WY G G+
Sbjct: 631 LEVVNSRSIKVSWLPPPSGTQNGFITGYKIRHRKTTRRGEMETLEPNNLWYLFTGLEKGS 690
Query: 672 QTSTTLKLSPYVHYTFRVTAINKYGPGEPSPVSETVVTPEAAPEKNPVDVKGEG----NE 727
Q Y+F+V+A+ G G PS T TPE +++ V + +
Sbjct: 691 Q------------YSFQVSAMTVNGTGPPSNWY-TAETPENDLDESQVPDQPSSLHVRPQ 737
Query: 728 TTNMVITWKPLRWMDWNAPQVQYRVQWRPQGTRGPWQEQIVSDP---FLVVSNTSTFVPY 784
T ++++W P P + R G P+ E + D + + + Y
Sbjct: 738 TNCIIMSWTPPL-----NPNIVVRGYIIGYGVGSPYAETVRVDSKQRYYSIERLESSSHY 792
Query: 785 EIKVQAVNSQGKG------------PEPQVTIGYSG--EDYPQAIPELE-------GIEI 823
I ++A N+ G+G +P + Y +D+P ++P+L G++
Sbjct: 793 VISLKAFNNAGEGVPLYESATTRSITDPTDPVDYYPLLDDFPTSVPDLSTPMLPPVGVQA 852
Query: 824 --LNSSAVLVKW--RPVDLAQVKGHLRGYNVTYWREGSQRKHSKRHIHKDHVVVPANTTS 879
L AV V W V Q +R Y V WR S ++ +D + S
Sbjct: 853 VALTHDAVRVSWADNSVPKNQKTSEVRLYTVR-WRTSFSA--SAKYKSED-----TTSLS 904
Query: 880 VILSGLRPYSSYHLEVQAFNGRGSGPASEFTFST-----PEGVPGHPEALHLECQSNTSL 934
+GL+P + Y V R S S +T P P + E + ++
Sbjct: 905 YTATGLKPNTMYEFSVMVTKNRRSSTWSMTAHATTYEAAPTSAPKDLTVITREGKPR-AV 963
Query: 935 LLRWQPPLSHNGVLTGYVLSYH-----PLDEGGKGQLSFNLRDPELRTHNLTDLSPHLRY 989
++ WQPPL NG +T Y+L Y P+D+ +S + TH + DL+ Y
Sbjct: 964 IVSWQPPLEANGKITAYILFYTLDKNIPIDDWIMETIS-----GDRLTHQIMDLNLDTMY 1018
Query: 990 RFQLQATTKEGPG 1002
F++QA +G G
Sbjct: 1019 YFRIQARNSKGVG 1031
Score = 35.8 bits (81), Expect = 0.26
Identities = 55/230 (23%), Positives = 80/230 (34%), Gaps = 32/230 (13%)
Query: 40 QSPRRLVVFPTDDISLKCEASGKPEVQFRWTRDGVHFKPKEELGVTVYQSPHSGSFTITG 99
Q P +V D L+C SG P F W R G V Q + G
Sbjct: 244 QRPSNVVAIEGKDAVLECCVSGYPPPSFTWLR-----------GEEVIQLRSKKYSLLGG 292
Query: 100 NN---SNFAQRFQGIYRCFASNK-LGTAMSHEIRLMAEGAPKWPKETVKPVEVEEGESVV 155
+N SN G+Y C + K + S E+ ++ P W + E +
Sbjct: 293 SNLLISNVTDDDSGMYTCVVTYKNENISASAELTVL---VPPWFLNHPSNLYAYESMDIE 349
Query: 156 LPCNPPPSAEPLRIYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAH--- 212
C P + WM + + I D +G NL V+ SD Y C A
Sbjct: 350 FECTVSGKPVP-TVNWMKNGDVVIPSDYFQIVG-GSNLRILGVVKSD-EGFYQCVAENEA 406
Query: 213 ---FPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQP 259
+ I+ K I ++S++ PR + P SS V L +P
Sbjct: 407 GNAQTSAQLIVPKPAI-----PSSSVLPSAPRDVVPVLVSSRFVRLSWRP 451
Score = 32.7 bits (73), Expect = 2.2
Identities = 58/322 (18%), Positives = 114/322 (35%), Gaps = 50/322 (15%)
Query: 621 SDLHLLTQSQ-VRVSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTL-K 678
S LH+ Q+ + +SW+P + N + Y I + + +V Q ++ +
Sbjct: 730 SSLHVRPQTNCIIMSWTPPLNPNIVVRGYIIGYG----VGSPYAETVRVDSKQRYYSIER 785
Query: 679 LSPYVHYTFRVTAINKYGPGEPSPVSETVVT-----------------PEAAPEKNPVDV 721
L HY + A N G G P S T + P + P+ + +
Sbjct: 786 LESSSHYVISLKAFNNAGEGVPLYESATTRSITDPTDPVDYYPLLDDFPTSVPDLSTPML 845
Query: 722 KGEGNETTNMVITWKPLRWMDWNAPQVQ-------YRVQWRPQ-GTRGPWQEQIVSDPFL 773
G + + + W D + P+ Q Y V+WR ++ + +
Sbjct: 846 PPVGVQAVALTHDAVRVSWADNSVPKNQKTSEVRLYTVRWRTSFSASAKYKSEDTTSLSY 905
Query: 774 VVSNTSTFVPYEIKVQAVNSQGKGPEPQVTIGYSGEDYPQAIPELEGIEILNSS----AV 829
+ YE V ++ + E P + P+ + ++ AV
Sbjct: 906 TATGLKPNTMYEFSVMVTKNRRSSTWSMTAHATTYEAAPTSAPK--DLTVITREGKPRAV 963
Query: 830 LVKWRPVDLAQVKGHLRGYNVTYWREGSQRKHSKRHIHKDHVV---VPANTTSVILSGLR 886
+V W+P + G + Y + Y + ++I D + + + + + L
Sbjct: 964 IVSWQPP--LEANGKITAYILFYTLD--------KNIPIDDWIMETISGDRLTHQIMDLN 1013
Query: 887 PYSSYHLEVQAFNGRGSGPASE 908
+ Y+ +QA N +G GP S+
Sbjct: 1014 LDTMYYFRIQARNSKGVGPLSD 1035
>gi|157311649 neogenin homolog 1 [Homo sapiens]
Length = 1461
Score = 229 bits (583), Expect = 2e-59
Identities = 196/789 (24%), Positives = 340/789 (43%), Gaps = 72/789 (9%)
Query: 253 VALQGQPLVLECIAEGFPTPTIKW----------------LRPSGPMPADRVTYQNHNKT 296
++++G ++L C A P+P I+W L P G + V + HNK
Sbjct: 63 LSVRGSSVILNCSAYSEPSPKIEWKKDGTFLNLVSDDRRQLLPDGSLFISNVVHSKHNKP 122
Query: 297 LQLLKVGEEDDGEYRCLAE-NSLGS--ARHAYYVTVEAAPYWLHKPQSHLYGPGETARLD 353
D+G Y+C+A SLG+ +R A + V P + +P+ G A L+
Sbjct: 123 ---------DEGYYQCVATVESLGTIISRTAKLI-VAGLPRFTSQPEPSSVYAGNNAILN 172
Query: 354 CQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLL 413
C+V P V W N P+ L D+ ++ G L++SN D + +C + G
Sbjct: 173 CEVNADLVPFVRWEQNRQPL--LLDDRVIKLPSGMLVISNATEGDGGLYRCVVESG-GPP 229
Query: 414 LANAYIYVVQLPAKILTAD------NQTYMAVQGSTAYLLCKAFGAPVPSVQWL-DEDGT 466
+ + + LP + +D + V G L C A G P P+++W+ +E+
Sbjct: 230 KYSDEVELKVLPDPEVISDLVFLKQPSPLVRVIGQDVVLPCVASGLPTPTIKWMKNEEAL 289
Query: 467 TVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRS 526
ER A G+L I D+ +D G YFC+A N + A L V+ + + P +
Sbjct: 290 DTESSERLVLLAGGSLEISDVTEDDAGTYFCIADNGNETIEAQAELTVQAQPEFLKQPTN 349
Query: 527 TIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYSDQ 586
+ + F C+ + P+ P++ W +G D+ D K +++ L + L SD+
Sbjct: 350 IYAHESMDIVFECEVTGKPT--PTVKWVKNG-DMVIPSDYFK-IVKEHNLQVLGLVKSDE 405
Query: 587 GNYSCVASTELDVVESRAQLLVV----GSPGPVPRLVLSDLHLLTQSQ-VRVSW-SPAED 640
G Y C+A ++ ++ AQL+++ + GP+P + L ++ ++++W +PA D
Sbjct: 406 GFYQCIAENDVGNAQAGAQLIILEHAPATTGPLPSAPRDVVASLVSTRFIKLTWRTPASD 465
Query: 641 HNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAINKYGPGEP 700
+ Y + + + +A E+ + PG T L P Y FRV A NK+G GE
Sbjct: 466 PHGDNLTYSVFYTKEGIARERVENTSH-PGEMQVTIQNLMPATVYIFRVMAQNKHGSGES 524
Query: 701 SPVSETVVTPEAAPEKNPVDVKGEGNETTNMVITWKPLRWMDWNAPQVQYRVQWRPQGTR 760
S PE +++ T++ +TW+ + N Y++ + +GT
Sbjct: 525 SAPLRVETQPEVQLPGPAPNLRAYAASPTSITVTWETP--VSGNGEIQNYKLYYMEKGT- 581
Query: 761 GPWQEQIVSDPFLVVSNTSTFVPYEIKVQAVNSQGKGPEPQVTIGYSGEDYPQAIPELEG 820
Q+ VS ++ + Y +V A N G G + D P A P+
Sbjct: 582 DKEQDVDVSSHSYTINGLKKYTEYSFRVVAYNKHGPGVSTPDVAVRTLSDVPSAAPQNLS 641
Query: 821 IEILNSSAVLVKWRPVDLAQVKGHLRGYNVTYWREGSQRKHSKRHIHKDHVVVPANTTSV 880
+E+ NS ++++ W+P A G + GY + Y + + R +V S
Sbjct: 642 LEVRNSKSIMIHWQPPAPATQNGQITGYKIRY-------RKASRKSDVTETLVSGTQLSQ 694
Query: 881 ILSGLRPYSSYHLEVQAFNGRGSGPASEF----TFST---PEGVPGHPEALHLECQSNTS 933
++ GL + Y+ V A G+GPA+++ TF + VP P +LH+ TS
Sbjct: 695 LIEGLDRGTEYNFRVAALTINGTGPATDWLSAETFESDLDETRVPEVPSSLHVR-PLVTS 753
Query: 934 LLLRWQPPLSHNGVLTGYVLSYHPLDEGGKGQLSFNLRDPELRTHNLTDLSPHLRYRFQL 993
+++ W PP + N V+ GY + Y G D + R + + +L P Y L
Sbjct: 754 IVVSWTPPENQNIVVRGYAIGYGI----GSPHAQTIKVDYKQRYYTIENLDPSSHYVITL 809
Query: 994 QATTKEGPG 1002
+A G G
Sbjct: 810 KAFNNVGEG 818
Score = 145 bits (365), Expect = 3e-34
Identities = 231/1037 (22%), Positives = 395/1037 (38%), Gaps = 121/1037 (11%)
Query: 41 SPRRLVVFPTDDIS-------LKCEASGKPEVQFRWTRDGVHFKPKEELGVTVYQSPHSG 93
+P +V P D +S L C A +P + W +DG + + P
Sbjct: 51 TPFYFLVEPVDTLSVRGSSVILNCSAYSEPSPKIEWKKDGTFLNLVSDDRRQLL--PDGS 108
Query: 94 SFTITGNNSNFAQRFQGIYRCFAS-NKLGTAMSHEIRLMAEGAPKWPKETVKPVEVEEGE 152
F +S + +G Y+C A+ LGT +S +L+ G P++ + +P V G
Sbjct: 109 LFISNVVHSKHNKPDEGYYQCVATVESLGTIISRTAKLIVAGLPRFTSQP-EPSSVYAGN 167
Query: 153 SVVLPCNPPPSAEPLRIYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAH 212
+ +L C P + N + L + D+RV +G L +N D Y C
Sbjct: 168 NAILNCEVNADLVPFVRWEQNRQPLLL--DDRVIKLPSGMLVISNATEGDGGL-YRCVVE 224
Query: 213 FPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTP 272
G + ++L+V +I L P S LV + GQ +VL C+A G PTP
Sbjct: 225 SGGPPKY--SDEVELKVLPDPEVISDLVFLKQP----SPLVRVIGQDVVLPCVASGLPTP 278
Query: 273 TIKWLRPSGPM---PADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTV 329
TIKW++ + ++R+ +L++ V E+D G Y C+A+N + +TV
Sbjct: 279 TIKWMKNEEALDTESSERLVLL-AGGSLEISDVTEDDAGTYFCIADNGNETIEAQAELTV 337
Query: 330 EAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGAL 389
+A P +L +P + +C+V G+P P V W NG V + D ++ L
Sbjct: 338 QAQPEFLKQPTNIYAHESMDIVFECEVTGKPTPTVKWVKNGDMV--IPSDYFKIVKEHNL 395
Query: 390 ILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQ-LPAKI--LTADNQTYMAVQGSTAYL 446
+ + SD QC A N G A A + +++ PA L + + +A ST ++
Sbjct: 396 QVLGLVKSDEGFYQCIAENDVGNAQAGAQLIILEHAPATTGPLPSAPRDVVASLVSTRFI 455
Query: 447 -------LCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLA 499
G + + ++G + E + I++L + +A
Sbjct: 456 KLTWRTPASDPHGDNLTYSVFYTKEGIARERVENTSHPGEMQVTIQNLMPATVYIFRVMA 515
Query: 500 ANDQNNVTIMANLKVKDATQI-TQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGR 558
N + A L+V+ ++ GP + + T ++TW
Sbjct: 516 QNKHGSGESSAPLRVETQPEVQLPGPAPNLRAYAASPT-----------SITVTWETPVS 564
Query: 559 DLQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGSPGP---- 614
E+ + Y++E G +D S ++S + E +++ GP
Sbjct: 565 GNGEIQNYKLYYMEKGTDKEQDVDVS---SHSYTINGLKKYTEYSFRVVAYNKHGPGVST 621
Query: 615 --VPRLVLSD----------LHLLTQSQVRVSWSP--AEDHNAPIEKYDIEFEDKEMAPE 660
V LSD L + + + W P N I Y I + +
Sbjct: 622 PDVAVRTLSDVPSAAPQNLSLEVRNSKSIMIHWQPPAPATQNGQITGYKIRYRKASRKSD 681
Query: 661 KWYSLGKVPGNQTSTTLK-LSPYVHYTFRVTAINKYGPGEPSPVSETVVTPEAAPEKNPV 719
+L V G Q S ++ L Y FRV A+ G G + E
Sbjct: 682 VTETL--VSGTQLSQLIEGLDRGTEYNFRVAALTINGTGPATDWLSAETFESDLDETRVP 739
Query: 720 DVKGEGNE---TTNMVITWKPLRWMDWNAPQVQYRVQWRPQGTRGPWQEQIVSD---PFL 773
+V + T++V++W P + N Y + + G P + I D +
Sbjct: 740 EVPSSLHVRPLVTSIVVSWTPPE--NQNIVVRGYAIGY---GIGSPHAQTIKVDYKQRYY 794
Query: 774 VVSNTSTFVPYEIKVQAVNSQGKGPEPQVTIGYSGEDYPQAIPELEGIEILNSSAVLV-- 831
+ N Y I ++A N+ G+G + + S P + ++N+ V
Sbjct: 795 TIENLDPSSHYVITLKAFNNVGEG----IPLYESAVTRPHTDTSEVDLFVINAPYTPVPD 850
Query: 832 ---KWRPVDL-AQVKGHLRGYNVTYWREGSQRKHSKRHIHKDHVV-----VPAN------ 876
PV + A + H +T W + S KH K + + V +PAN
Sbjct: 851 PTPMMPPVGVQASILSH-DTIRIT-WADNSLPKHQKITDSRYYTVRWKTNIPANTKYKNA 908
Query: 877 ---TTSVILSGLRPYSSYHLEVQAFNGRGSGPASEFTFST-----PEGVPGHPEALHLEC 928
T S +++GL+P + Y V GR S S T P P + E
Sbjct: 909 NATTLSYLVTGLKPNTLYEFSVMVTKGRRSSTWSMTAHGTTFELVPTSPPKDVTVVSKEG 968
Query: 929 QSNTSLLLRWQPPLSHNGVLTGYVLSYHPLDEGGKGQLSFNLRDPEL---RTHNLTDLSP 985
+ T +++ WQPP NG +TGY++ Y ++ + +P + TH + +L+
Sbjct: 969 KPKT-IIVNWQPPSEANGKITGYIIYY---STDVNAEIHDWVIEPVVGNRLTHQIQELTL 1024
Query: 986 HLRYRFQLQATTKEGPG 1002
Y F++QA +G G
Sbjct: 1025 DTPYYFKIQARNSKGMG 1041
Score = 52.4 bits (124), Expect = 3e-06
Identities = 79/344 (22%), Positives = 130/344 (37%), Gaps = 78/344 (22%)
Query: 619 VLSDLHLLTQ-SQVRVSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLG-------KVPG 670
V S LH+ + + VSW+P E+ N + Y I Y +G KV
Sbjct: 741 VPSSLHVRPLVTSIVVSWTPPENQNIVVRGYAIG-----------YGIGSPHAQTIKVDY 789
Query: 671 NQTSTTLK-LSPYVHYTFRVTAINKYGPGEPSPVSETVVT-------------------- 709
Q T++ L P HY + A N G G P+ E+ VT
Sbjct: 790 KQRYYTIENLDPSSHYVITLKAFNNVGEG--IPLYESAVTRPHTDTSEVDLFVINAPYTP 847
Query: 710 -PEAAPEKNPVDVKGEGNETTNMVITWKPLRWMDWNAPQVQ-------YRVQWR---PQG 758
P+ P PV V+ + ITW D + P+ Q Y V+W+ P
Sbjct: 848 VPDPTPMMPPVGVQASILSHDTIRITWA-----DNSLPKHQKITDSRYYTVRWKTNIPAN 902
Query: 759 TRGPWQEQIVSDPFLVVSNTSTFVPYEIKVQAVNSQGKGPEPQVTIGYSGEDYPQAIPEL 818
T+ ++ + +V+ YE V + G + E P + P+
Sbjct: 903 TK--YKNANATTLSYLVTGLKPNTLYEFSVMVTKGRRSSTWSMTAHGTTFELVPTSPPK- 959
Query: 819 EGIEILNSSA----VLVKWRPVDLAQVKGHLRGYNVTYWREGSQRKHSKRHIHKDHVVVP 874
+ +++ ++V W+P ++ G + GY + Y + + H D V+ P
Sbjct: 960 -DVTVVSKEGKPKTIIVNWQPP--SEANGKITGYIIYYSTDVNAEIH-------DWVIEP 1009
Query: 875 A--NTTSVILSGLRPYSSYHLEVQAFNGRGSGPASE-FTFSTPE 915
N + + L + Y+ ++QA N +G GP SE F TP+
Sbjct: 1010 VVGNRLTHQIQELTLDTPYYFKIQARNSKGMGPMSEAVQFRTPK 1053
Score = 38.1 bits (87), Expect = 0.053
Identities = 22/97 (22%), Positives = 42/97 (43%), Gaps = 9/97 (9%)
Query: 40 QSPRRLVVFPTDDISLKCEASGKPEVQFRWTRDGVHFKPKEELGVTVYQSPHSGSFTITG 99
+ P + + DI +CE +GKP +W ++G P + ++ + + G
Sbjct: 345 KQPTNIYAHESMDIVFECEVTGKPTPTVKWVKNGDMVIPSD-----YFKIVKEHNLQVLG 399
Query: 100 NNSNFAQRFQGIYRCFASNKLGTAMSHEIRLMAEGAP 136
+ +G Y+C A N +G A + ++ E AP
Sbjct: 400 ----LVKSDEGFYQCIAENDVGNAQAGAQLIILEHAP 432
Score = 32.3 bits (72), Expect = 2.9
Identities = 38/165 (23%), Positives = 65/165 (39%), Gaps = 18/165 (10%)
Query: 24 EEYEGHHVMEPPVITE----QSPRRLVVFPTDDISLKCEASGKPEVQFRWTR--DGVHFK 77
+E E + +P VI++ + P LV D+ L C ASG P +W + + + +
Sbjct: 233 DEVELKVLPDPEVISDLVFLKQPSPLVRVIGQDVVLPCVASGLPTPTIKWMKNEEALDTE 292
Query: 78 PKEELGVTVYQSPHSGSFTITGNNSNFAQRFQGIYRCFASNKLGTAMSHEIRLMAEGAPK 137
E L + GS I S+ + G Y C A N T + + L + P+
Sbjct: 293 SSERLVLLA-----GGSLEI----SDVTEDDAGTYFCIADNGNET-IEAQAELTVQAQPE 342
Query: 138 WPKETVKPVEVEEGESVVLPCNPPPSAEPLRIYWMNSKILHIKQD 182
+ K+ + E +V C P + W+ + + I D
Sbjct: 343 FLKQPTN-IYAHESMDIVFECEVTGKPTP-TVKWVKNGDMVIPSD 385
>gi|21359935 Down syndrome cell adhesion molecule like 1 [Homo
sapiens]
Length = 2113
Score = 205 bits (521), Expect = 3e-52
Identities = 246/1033 (23%), Positives = 399/1033 (38%), Gaps = 86/1033 (8%)
Query: 35 PVITEQSPRRLVVFPTDDISLKCEASGKPEVQFRWTRDGVHFKPKEELGVTVYQSPHSGS 94
P+ +P++L + L C +G PE RW R+ P E + + + + +
Sbjct: 374 PLHVTLTPKKLKTGIGSTVILSCALTGSPEFTIRWYRNTELVLPDEAISI---RGLSNET 430
Query: 95 FTITGNNSNFAQRFQGIYRCFASNKLGTAMSHEIRLMAEGAPKWPKETVKPVEVEEGESV 154
IT + + G Y+CFA+ K TA I + +G P+ + V V GE
Sbjct: 431 LLITSAQKSHS----GAYQCFATRKAQTAQDFAIIALEDGTPRIVSSFSEKV-VNPGEQF 485
Query: 155 VLPCNPPPSAEPLRIYWMNSKILHIKQDERV---TMGQNGNLYFANVLTSDNHSD---YI 208
L C + P + ++ + + R TM + NV T D Y
Sbjct: 486 SLMCAAKGAPPPTVTWALDDEPIVRDGSHRTNQYTMSDGTTISHMNV-TGPQIRDGGVYR 544
Query: 209 CHAHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEG 268
C A R ++ R+ R R ++ A+ G+ ++ C G
Sbjct: 545 CTA-----RNLVGSAEYQARINVRGPPSIRAMR---------NITAVAGRDTLINCRVIG 590
Query: 269 FPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEE-DDGEYRC--LAENSLGSARHAY 325
+P +IKW + + +P + N TL+L V + D+GEY C L + L S +
Sbjct: 591 YPYYSIKWYKDALLLPDNHRQVVFENGTLKLTDVQKGMDEGEYLCSVLIQPQL-SISQSV 649
Query: 326 YVTVEAAPYWLHKPQSHLYGP---GETARLDCQVQGRPQP-EVTWRING-IPVEELAKDQ 380
+V V+ P Q + P G+ + C V P +TWR +G + +
Sbjct: 650 HVAVKVPPLI----QPFEFPPASIGQLLYIPCVVSSGDMPIRITWRKDGQVIISGSGVTI 705
Query: 381 KYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQTYMAVQ 440
+ + +L +S+V C A N + + V P ++ +NQ +
Sbjct: 706 ESKEFMSSLQISSVSLKHNGNYTCIASNAAATVSRERQLIVRVPPRFVVQPNNQD--GIY 763
Query: 441 GSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYA-------NGTLGIRDLQANDTG 493
G L C G P P V W G+ Q P N +L IR + D G
Sbjct: 764 GKAGVLNCSVDGYPPPKVMWKHAKGSGNPQQYHPVPLTGRIQILPNSSLLIRHVLEEDIG 823
Query: 494 RYFCLAANDQN-NVTIMANLKVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSIT 552
Y C A+N +++ L VK IT P +TI KG C A + +P I
Sbjct: 824 YYLCQASNGVGTDISKSMFLTVKIPAMITSHPNTTIAIKGHAKELNCTARGE---RPIII 880
Query: 553 WRGDGRDLQELGDSDKYFI---EDGRLVIHSL-----DYSDQGNYSCVASTELDVVESRA 604
G + + +Y I ++G V+ +L D D +SC A
Sbjct: 881 RWEKGDTVIDPDRVMRYAIATKDNGDEVVSTLKLKPADRGDSVFFSCHAINSYGEDRGLI 940
Query: 605 QLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYS 664
QL V P P P L + ++ + + + W+ D N+ I +DIE+++K + + S
Sbjct: 941 QLTVQEPPDP-PELEIREVKARSMN---LRWTQRFDGNSIITGFDIEYKNKSDSWDFKQS 996
Query: 665 LGKV-PGNQTSTTLKLSPYVHYTFRVTAINKYGPGEPSPVSETVVTPEAAPEKNPVDVKG 723
+ P + + L P Y+ R+ + NK G EPS T+ T EAAP+ P+DV
Sbjct: 997 TRNISPTINQANIVDLHPASVYSIRMYSFNKIGRSEPSK-ELTISTEEAAPDGPPMDVTL 1055
Query: 724 EGNETTNMVITWKPLRWMDWNAPQVQYRVQWRPQGTRGPWQEQIVS------DPFLVVSN 777
+ + ++ +TWK + N Y++ +R Q IV + N
Sbjct: 1056 QPVTSQSIQVTWKAPKKELQNGVIRGYQIGYRENSPGSNGQYSIVEMKATGDSEVYTLDN 1115
Query: 778 TSTFVPYEIKVQAVNSQGKGPEPQVTIGYSGEDYPQAIPELEGIEILNSSAVLVKWRPVD 837
F Y + VQA N G GP + ED P PE + S ++ W
Sbjct: 1116 LKKFAQYGVVVQAFNRAGTGPSSSEINATTLEDVPSQPPENVRALSITSDVAVISWSEPP 1175
Query: 838 LAQVKGHLRGYNVTYWREGSQRKHSKRHIHKDHVVVPANTTSVILSGLRPYSSYHLEVQA 897
+ + G L+GY V +W + + + V L G+ +++Y ++V A
Sbjct: 1176 RSTLNGVLKGYRVIFWSLYVDGEWGEMQ------NITTTRERVELRGMEKFTNYSVQVLA 1229
Query: 898 FNGRGSGPASEFTF-STPEGVPGHPEALHLECQSNTSLLLRWQPPLSHNGVLTGYVLSYH 956
+ G G S + T E VPG P + S +S+++ W PP NGV+ Y +
Sbjct: 1230 YTQAGDGVRSSVLYIQTKEDVPGPPAGIKAVPSSASSVVVSWLPPTKPNGVIRKYTIFCS 1289
Query: 957 PLDEGGKGQLSFNLRDPELRTHNLTDLSPHLRYRFQLQATTKEGPG---EAIVREGGTMA 1013
G + PE + + L+ +Y + A T G G E + E A
Sbjct: 1290 SPGSGQPAPSEYE-TSPEQLFYRIAHLNRGQQYLLWVAAVTSAGRGNSSEKVTIEPAGKA 1348
Query: 1014 LSGISDFGNISAT 1026
+ I FG T
Sbjct: 1349 PAKIISFGGTVTT 1361
Score = 104 bits (260), Expect = 5e-22
Identities = 135/560 (24%), Positives = 211/560 (37%), Gaps = 48/560 (8%)
Query: 53 ISLKCEASGKPEVQFRWTRDGVHFKPKEELGVTVYQSPH------SGSFTITGNNSNFAQ 106
+ + C A+G P RW G +Y PH +G+ + + +
Sbjct: 103 VVVPCPAAGSPSAALRWYL---------ATGDDIYDVPHIRHVHANGTLQLYPFSPSAFN 153
Query: 107 RF--QGIYRCFASNKLGTAMSHEIRLMAEGAPKWPKETVKPVEVEEGESVVLPCNPPPSA 164
F Y C A N G S IR+ A + V+ G V C P S
Sbjct: 154 SFIHDNDYFCTAENAAGKIRSPNIRVKAVFREPYTVR-VEDQRSMRGNVAVFKCLIPSSV 212
Query: 165 -EPLRIYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAHFPGTRTIIQKE 223
E + + + I + R + +G LY ++V D S Y C + Q
Sbjct: 213 QEYVSVVSWEKDTVSIIPEHRFFITYHGGLYISDVQKEDALSTYRCITKHKYSGETRQSN 272
Query: 224 PIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPM 283
L V I P +L +S G + L C A G+P P I+WL+ P+
Sbjct: 273 GARLSVTDPAESI---PTILDGFHSQE---VWAGHTVELPCTASGYPIPAIRWLKDGRPL 326
Query: 284 PAD-RVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVEAAPYWLHKPQSH 342
PAD R T + T+ L+ ED G Y C N+ GSA + V + P+
Sbjct: 327 PADSRWTKRITGLTISDLRT--EDSGTYICEVTNTFGSAEATGILMVIDPLHVTLTPKKL 384
Query: 343 LYGPGETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQ---RGALILSNVQPSDT 399
G G T L C + G P+ + W N E + D+ I+ L++++ Q S +
Sbjct: 385 KTGIGSTVILSCALTGSPEFTIRWYRN---TELVLPDEAISIRGLSNETLLITSAQKSHS 441
Query: 400 MVTQCEARNRHGLLLANAYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQ 459
QC A + A I + +I+++ ++ + G L+C A GAP P+V
Sbjct: 442 GAYQCFATRKAQTAQDFAIIALEDGTPRIVSSFSEK-VVNPGEQFSLMCAAKGAPPPTVT 500
Query: 460 WLDEDGTTVLQDE---RFFPYANGT----LGIRDLQANDTGRYFCLAANDQNNVTIMANL 512
W +D V + ++GT + + Q D G Y C A N + A +
Sbjct: 501 WALDDEPIVRDGSHRTNQYTMSDGTTISHMNVTGPQIRDGGVYRCTARNLVGSAEYQARI 560
Query: 513 KVKDATQITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIE 572
V+ I + R+ G C+ P SI W D L + + + E
Sbjct: 561 NVRGPPSI-RAMRNITAVAGRDTLINCRVIGYPYY--SIKWYKDALLLPD--NHRQVVFE 615
Query: 573 DGRLVIHSLDYS-DQGNYSC 591
+G L + + D+G Y C
Sbjct: 616 NGTLKLTDVQKGMDEGEYLC 635
Score = 84.3 bits (207), Expect = 6e-16
Identities = 97/400 (24%), Positives = 163/400 (40%), Gaps = 31/400 (7%)
Query: 242 LLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPAD--RVTYQNHNKTLQL 299
L F +S + +V+ C A G P+ ++W +G D + + + N TLQL
Sbjct: 85 LYFVNDSLQQVTFSSSVGVVVPCPAAGSPSAALRWYLATGDDIYDVPHIRHVHANGTLQL 144
Query: 300 LKVGEE------DDGEYRCLAENSLGSAR--HAYYVTVEAAPYWLHKPQSHLYGPGETAR 351
D +Y C AEN+ G R + V PY + + + G A
Sbjct: 145 YPFSPSAFNSFIHDNDYFCTAENAAGKIRSPNIRVKAVFREPYTV-RVEDQRSMRGNVAV 203
Query: 352 LDCQVQGRPQ---PEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVT-QCEAR 407
C + Q V+W + + + + + + + G L +S+VQ D + T +C +
Sbjct: 204 FKCLIPSSVQEYVSVVSWEKDTVSI--IPEHRFFITYHGGLYISDVQKEDALSTYRCITK 261
Query: 408 NRHG--LLLANAYIYVVQLPAKILTADNQTYMAVQ---GSTAYLLCKAFGAPVPSVQWLD 462
+++ +N V PA+ + + + + G T L C A G P+P+++WL
Sbjct: 262 HKYSGETRQSNGARLSVTDPAESIPTILDGFHSQEVWAGHTVELPCTASGYPIPAIRWL- 320
Query: 463 EDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQ 522
+DG + D R+ G L I DL+ D+G Y C N + L V D +T
Sbjct: 321 KDGRPLPADSRWTKRITG-LTISDLRTEDSGTYICEVTNTFGSAEATGILMVIDPLHVTL 379
Query: 523 GPRSTIEKKGSRVTFTCQASFDPSLQPSITW-RGDGRDLQELGDSDKYFIEDGRLVIHSL 581
P+ GS V +C + P +I W R L + S + + + L+I S
Sbjct: 380 TPKKLKTGIGSTVILSCALTGSPEF--TIRWYRNTELVLPDEAISIR-GLSNETLLITSA 436
Query: 582 DYSDQGNYSCVASTELDVVESRAQLLVVGSPGPVPRLVLS 621
S G Y C A+ + + A ++ PR+V S
Sbjct: 437 QKSHSGAYQCFATRKAQTAQDFA---IIALEDGTPRIVSS 473
Score = 59.3 bits (142), Expect = 2e-08
Identities = 67/288 (23%), Positives = 118/288 (40%), Gaps = 27/288 (9%)
Query: 535 VTFTCQASFDPSLQPSITWRGDGRD--LQELGDSDKYFIEDGRLVIHSLDYSDQGNYSCV 592
V C + DP+ P++ W D D + D + +G L++ ++ D G Y+C
Sbjct: 1367 VRLPCNSVGDPA--PAVKWTKDSEDSAIPVSMDGHRLIHTNGTLLLRAVKAEDSGYYTCT 1424
Query: 593 ASTELDVVESRAQLLVVGSPGPVPRLVLSDLHLLTQSQVRVSWSPAEDHNAPIEKYDIEF 652
A T ++ L+V P PRL +S + S + ++W P ++ + I + +++
Sbjct: 1425 A-TNTGGFDTIIVNLLVQVPPDQPRLTVSK---TSASSITLTWIPGDNGGSSIRGFVLQY 1480
Query: 653 EDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAINKYGPGEPSPVSETVVTPEA 712
E+W + ++ L Y ++ A N G G +SE + EA
Sbjct: 1481 SVDN--SEEWKDVFISSSERSFKLDSLKCGTWYKVKLAAKNSVGSGR---ISEII---EA 1532
Query: 713 APEKNPVDVKGEGNETTNMVITWKPLRWMDWN---APQVQYRVQWRPQGTRGPWQ---EQ 766
+ + T++ T L WN P +++RP+GT WQ
Sbjct: 1533 KTHGREPSFSKDQHLFTHINSTHARLNLQGWNNGGCPITAIVLEYRPKGT-WAWQGLRAN 1591
Query: 767 IVSDPFLVVSNTSTFVPYEIKVQAVNSQGKGPEPQ--VTIGYSGEDYP 812
+ FL +T+ YE++++A NS G G E T+ Y G P
Sbjct: 1592 SSGEVFLTELREATW--YELRMRACNSAGCGNETAQFATLDYDGSTIP 1637
Score = 49.7 bits (117), Expect = 2e-05
Identities = 38/118 (32%), Positives = 54/118 (45%), Gaps = 8/118 (6%)
Query: 425 PAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWL---DEDGTTVLQDERFFPYANGT 481
PAKI++ T L C + G P P+V+W ++ V D + NGT
Sbjct: 1349 PAKIISFGG-TVTTPWMKDVRLPCNSVGDPAPAVKWTKDSEDSAIPVSMDGHRLIHTNGT 1407
Query: 482 LGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQGPRSTIEK-KGSRVTFT 538
L +R ++A D+G Y C A N TI+ NL V+ PR T+ K S +T T
Sbjct: 1408 LLLRAVKAEDSGYYTCTATNTGGFDTIIVNLLVQVP---PDQPRLTVSKTSASSITLT 1462
Score = 37.7 bits (86), Expect = 0.070
Identities = 23/62 (37%), Positives = 29/62 (46%), Gaps = 4/62 (6%)
Query: 262 LECIAEGFPTPTIKWLRPSG----PMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENS 317
L C + G P P +KW + S P+ D + N TL L V ED G Y C A N+
Sbjct: 1369 LPCNSVGDPAPAVKWTKDSEDSAIPVSMDGHRLIHTNGTLLLRAVKAEDSGYYTCTATNT 1428
Query: 318 LG 319
G
Sbjct: 1429 GG 1430
>gi|4506569 roundabout 1 isoform a [Homo sapiens]
Length = 1651
Score = 204 bits (518), Expect = 6e-52
Identities = 224/865 (25%), Positives = 356/865 (41%), Gaps = 95/865 (10%)
Query: 118 NKLGTAMSHEIRLMAEGAPKWPKETVKPVEVEEGESVVLPCNPPPSAEPLRIYWMNSKIL 177
N LG S RL E P E + V +GE L C P ++ + +
Sbjct: 52 NSLGYTGS---RLRQEDFPPRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERV 108
Query: 178 HIKQDERVT---MGQNGNLYFANVL----TSDNHSDYICHAHFPGTRTIIQKEPIDLRVK 230
+D+ + + +G+L+F ++ + + Y+C A + +++ +
Sbjct: 109 ETDKDDPRSHRMLLPSGSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAIL 168
Query: 231 ATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIA-EGFPTPTIKWLRPSGPMPA--DR 287
+ F N S +VA+ G+P V+EC G P PTI W + P+ +R
Sbjct: 169 RDD----------FRQNPSDVMVAV-GEPAVMECQPPRGHPEPTISWKKDGSPLDDKDER 217
Query: 288 VTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSAR-HAYYVTVEAAPYWLHKPQSHLYGP 346
+T + L + + D G+Y C+ N +G +TV P ++ +P +
Sbjct: 218 ITIRGGK--LMITYTRKSDAGKYVCVGTNMVGERESEVAELTVLERPSFVKRPSNLAVTV 275
Query: 347 GETARLDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEA 406
++A C+ +G P P V WR + EL K + L + V D C A
Sbjct: 276 DDSAEFKCEARGDPVPTVRWRKDD---GELPKSRYEIRDDHTLKIRKVTAGDMGSYTCVA 332
Query: 407 RNRHGLLLANAYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGT 466
N G A+A + V + P ++ +Q + G T C+A G P P++ W E
Sbjct: 333 ENMVGKAEASATLTVQEPPHFVVKPRDQ--VVALGRTVTFQCEATGNPQPAIFWRREGSQ 390
Query: 467 TVL-------QDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQ 519
+L RF G L I ++Q +D G Y C N ++ A L+V D
Sbjct: 391 NLLFSYQPPQSSSRFSVSQTGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIA 450
Query: 520 ------ITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIED 573
I QGP + +C A+ P P+I WR DG L DS +E+
Sbjct: 451 DRPPPVIRQGPVNQTVAVDGTFVLSCVATGSPV--PTILWRKDGV-LVSTQDSRIKQLEN 507
Query: 574 GRLVIHSLDYSDQGNYSCVASTELDVVESRAQLLV------VGSPGPV-PRLVLS----- 621
G L I D G Y+C+AST A + V V P P P L+ S
Sbjct: 508 GVLQIRYAKLGDTGRYTCIASTPSGEATWSAYIEVQEFGVPVQPPRPTDPNLIPSAPSKP 567
Query: 622 DLHLLTQSQVRVSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSP 681
++ ++++ V +SW P + A Y IE + W ++ + +TS L P
Sbjct: 568 EVTDVSRNTVTLSWQPNLNSGATPTSYIIE-AFSHASGSSWQTVAENVKTETSAIKGLKP 626
Query: 682 YVHYTFRVTAINKYGPGEPSPVSETVVTPEAAPEKNPVDVKGEGNETTNMVI-------- 733
Y F V A N YG +PS +S+ V T + P VD K E N V+
Sbjct: 627 NAIYLFLVRAANAYGISDPSQISDPVKTQDVLPTSQGVDHKQVQRELGNAVLHLHNPTVL 686
Query: 734 --TWKPLRW-MDWNAPQVQ-YRVQWRPQGT---RGPWQEQIVSDP---FLVVSNTSTFVP 783
+ + W +D + +Q Y++ +RP G W V P +V+ + V
Sbjct: 687 SSSSIEVHWTVDQQSQYIQGYKILYRPSGANHGESDWLVFEVRTPAKNSVVIPDLRKGVN 746
Query: 784 YEIKVQAVNSQGKGPEPQVTIGYSGEDYPQAIPELEGIEIL----NSSAVLVKWRPVDLA 839
YEIK + ++ +G + ++ + E+ P A P +G+ + N +A+LV W+P
Sbjct: 747 YEIKARPFFNEFQGADSEIKFAKTLEEAPSAPP--QGVTVSKNDGNGTAILVSWQPPPED 804
Query: 840 QVKGHLRGYNVTYWREGSQRKHSKRHIHKDHVVVPANTTSVILSGLRPYSSYHLEVQAFN 899
G ++ Y V W G++ ++ HI+K V +T SV++ L P Y +EV A
Sbjct: 805 TQNGMVQEYKV--WCLGNETRY---HINK---TVDGSTFSVVIPFLVPGIRYSVEVAAST 856
Query: 900 GRGSGPASE--FTFSTPEGVPGHPE 922
G GSG SE F G P PE
Sbjct: 857 GAGSGVKSEPQFIQLDAHGNPVSPE 881
Score = 191 bits (486), Expect = 3e-48
Identities = 148/509 (29%), Positives = 227/509 (44%), Gaps = 35/509 (6%)
Query: 34 PPVITEQSPRRLVVFPTDDISLKCEASGKPEVQFRWTRDGVHFKPKEELGVTVYQSPHSG 93
PP I E P L+V + +L C+A G+P W + G + ++ + SG
Sbjct: 67 PPRIVEH-PSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSG 125
Query: 94 S-FTITGNNSNFAQRFQGIYRCFASNKLGTAMSHEIRLMAEGAPKWPKETVKPVEVEEGE 152
S F + + ++ +G+Y C A N LG A+SH L ++ V V GE
Sbjct: 126 SLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILRDDFRQNPSDVMVAVGE 185
Query: 153 SVVLPCNPPPSAEPLRIYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAH 212
V+ C PP I W +DER+T+ + G L SD Y+C
Sbjct: 186 PAVMECQPPRGHPEPTISWKKDGSPLDDKDERITI-RGGKLMITYTRKSDA-GKYVC--- 240
Query: 213 FPGTRTIIQKEP--IDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFP 270
GT + ++E +L V S + R L + S+ +C A G P
Sbjct: 241 -VGTNMVGERESEVAELTVLERPSFVKRPSNLAVTVDDSAEF----------KCEARGDP 289
Query: 271 TPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVE 330
PT++W + G +P R ++ + TL++ KV D G Y C+AEN +G A + +TV+
Sbjct: 290 VPTVRWRKDDGELPKSRYEIRDDH-TLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQ 348
Query: 331 AAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRING-----IPVEELAKDQKYRI- 384
P+++ KP+ + G T C+ G PQP + WR G + ++ +
Sbjct: 349 EPPHFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVS 408
Query: 385 QRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQL----PAKILTAD--NQTYMA 438
Q G L ++NVQ SD C+ N G ++ AY+ V + P ++ NQT +A
Sbjct: 409 QTGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQGPVNQT-VA 467
Query: 439 VQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCL 498
V G T L C A G+PVP++ W + QD R NG L IR + DTGRY C+
Sbjct: 468 VDG-TFVLSCVATGSPVPTILWRKDGVLVSTQDSRIKQLENGVLQIRYAKLGDTGRYTCI 526
Query: 499 AANDQNNVTIMANLKVKDATQITQGPRST 527
A+ T A ++V++ Q PR T
Sbjct: 527 ASTPSGEATWSAYIEVQEFGVPVQPPRPT 555
Score = 174 bits (441), Expect = 5e-43
Identities = 201/825 (24%), Positives = 338/825 (40%), Gaps = 87/825 (10%)
Query: 237 DRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKT 296
D PR++ S L+ +G+P L C AEG PTPTI+W + + D+ ++H
Sbjct: 65 DFPPRIV---EHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRML 121
Query: 297 LQ-----LLKV-----GEEDDGEYRCLAENSLGSARHAYYVTVEAAPY---WLHKPQSHL 343
L L++ D+G Y C+A N LG A ++ ++E A + P +
Sbjct: 122 LPSGSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAV-SHNASLEVAILRDDFRQNPSDVM 180
Query: 344 YGPGETARLDCQV-QGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVT 402
GE A ++CQ +G P+P ++W+ +G P+++ KD++ I+ G L+++ + SD
Sbjct: 181 VAVGEPAVMECQPPRGHPEPTISWKKDGSPLDD--KDERITIRGGKLMITYTRKSDAGKY 238
Query: 403 QCEARNRHGLLLAN-AYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWL 461
C N G + A + V++ P+ + N +A C+A G PVP+V+W
Sbjct: 239 VCVGTNMVGERESEVAELTVLERPSFVKRPSNLAVTV--DDSAEFKCEARGDPVPTVRWR 296
Query: 462 DEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQIT 521
+DG L R+ + TL IR + A D G Y C+A N A L V++
Sbjct: 297 KDDGE--LPKSRYEIRDDHTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQEPPHFV 354
Query: 522 QGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRD-----LQELGDSDKYFI-EDGR 575
PR + G VTF C+A+ +P QP+I WR +G Q S ++ + + G
Sbjct: 355 VKPRDQVVALGRTVTFQCEATGNP--QPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGD 412
Query: 576 LVIHSLDYSDQGNYSCVASTELDVVESRAQLLV----------VGSPGPVPRLVLSDLHL 625
L I ++ SD G Y C + ++A L V V GPV + V D
Sbjct: 413 LTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQGPVNQTVAVDGTF 472
Query: 626 LTQSQVRVSWSPA---EDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPY 682
+ S P + D + E + K+ T + +P
Sbjct: 473 VLSCVATGSPVPTILWRKDGVLVSTQDSRIKQLENGVLQ-IRYAKLGDTGRYTCIASTPS 531
Query: 683 VHYTFRV-TAINKYG-PGEPSPVSETVVTPEAAPEKNPVDVKGEGNETTNMVITWKPLRW 740
T+ + ++G P +P ++ + P A + DV + ++W+P
Sbjct: 532 GEATWSAYIEVQEFGVPVQPPRPTDPNLIPSAPSKPEVTDVS-----RNTVTLSWQPN-- 584
Query: 741 MDWNAPQVQYRVQWRPQGTRGPWQE--QIVSDPFLVVSNTSTFVPYEIKVQAVNSQGKGP 798
++ A Y ++ + WQ + V + Y V+A N+ G
Sbjct: 585 LNSGATPTSYIIEAFSHASGSSWQTVAENVKTETSAIKGLKPNAIYLFLVRAANAYGISD 644
Query: 799 EPQVTIGYS---------GEDYPQ-------AIPELEGIEILNSSAVLVKWRPVDLAQVK 842
Q++ G D+ Q A+ L +L+SS++ V W + Q
Sbjct: 645 PSQISDPVKTQDVLPTSQGVDHKQVQRELGNAVLHLHNPTVLSSSSIEVHWT---VDQQS 701
Query: 843 GHLRGYNVTYWREGSQRKHSKRHIHKDHVVVPANTTSVILSGLRPYSSYHLEVQAFNGRG 902
+++GY + Y G+ S + + V PA SV++ LR +Y ++ + F
Sbjct: 702 QYIQGYKILYRPSGANHGESDWLVFE--VRTPAKN-SVVIPDLRKGVNYEIKARPFFNEF 758
Query: 903 SGPASEFTFS-TPEGVPGHPE---ALHLECQSNTSLLLRWQPPLSHNGVLTGYVLSYHPL 958
G SE F+ T E P P + + T++L+ WQPP G V Y
Sbjct: 759 QGADSEIKFAKTLEEAPSAPPQGVTVSKNDGNGTAILVSWQPP--PEDTQNGMVQEYKVW 816
Query: 959 DEGGKGQLSFNLR-DPELRTHNLTDLSPHLRYRFQLQATTKEGPG 1002
G + + N D + + L P +RY ++ A+T G G
Sbjct: 817 CLGNETRYHINKTVDGSTFSVVIPFLVPGIRYSVEVAASTGAGSG 861
>gi|19743806 roundabout 1 isoform b [Homo sapiens]
Length = 1612
Score = 203 bits (517), Expect = 7e-52
Identities = 220/854 (25%), Positives = 352/854 (41%), Gaps = 92/854 (10%)
Query: 129 RLMAEGAPKWPKETVKPVEVEEGESVVLPCNPPPSAEPLRIYWMNSKILHIKQDERVT-- 186
RL E P E + V +GE L C P ++ + + +D+ +
Sbjct: 21 RLRQEDFPPRIVEHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHR 80
Query: 187 -MGQNGNLYFANVL----TSDNHSDYICHAHFPGTRTIIQKEPIDLRVKATNSMIDRKPR 241
+ +G+L+F ++ + + Y+C A + +++ + +
Sbjct: 81 MLLPSGSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILRDD-------- 132
Query: 242 LLFPTNSSSHLVALQGQPLVLECIA-EGFPTPTIKWLRPSGPMPA--DRVTYQNHNKTLQ 298
F N S +VA+ G+P V+EC G P PTI W + P+ +R+T + L
Sbjct: 133 --FRQNPSDVMVAV-GEPAVMECQPPRGHPEPTISWKKDGSPLDDKDERITIRGGK--LM 187
Query: 299 LLKVGEEDDGEYRCLAENSLGSAR-HAYYVTVEAAPYWLHKPQSHLYGPGETARLDCQVQ 357
+ + D G+Y C+ N +G +TV P ++ +P + ++A C+ +
Sbjct: 188 ITYTRKSDAGKYVCVGTNMVGERESEVAELTVLERPSFVKRPSNLAVTVDDSAEFKCEAR 247
Query: 358 GRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHGLLLANA 417
G P P V WR + EL K + L + V D C A N G A+A
Sbjct: 248 GDPVPTVRWRKDD---GELPKSRYEIRDDHTLKIRKVTAGDMGSYTCVAENMVGKAEASA 304
Query: 418 YIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVL-------Q 470
+ V + P ++ +Q + G T C+A G P P++ W E +L
Sbjct: 305 TLTVQEPPHFVVKPRDQ--VVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQS 362
Query: 471 DERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQ------ITQGP 524
RF G L I ++Q +D G Y C N ++ A L+V D I QGP
Sbjct: 363 SSRFSVSQTGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQGP 422
Query: 525 RSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVIHSLDYS 584
+ +C A+ P P+I WR DG L DS +E+G L I
Sbjct: 423 VNQTVAVDGTFVLSCVATGSPV--PTILWRKDGV-LVSTQDSRIKQLENGVLQIRYAKLG 479
Query: 585 DQGNYSCVASTELDVVESRAQLLV------VGSPGPV-PRLVLS-----DLHLLTQSQVR 632
D G Y+C+AST A + V V P P P L+ S ++ ++++ V
Sbjct: 480 DTGRYTCIASTPSGEATWSAYIEVQEFGVPVQPPRPTDPNLIPSAPSKPEVTDVSRNTVT 539
Query: 633 VSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHYTFRVTAI 692
+SW P + A Y IE + W ++ + +TS L P Y F V A
Sbjct: 540 LSWQPNLNSGATPTSYIIE-AFSHASGSSWQTVAENVKTETSAIKGLKPNAIYLFLVRAA 598
Query: 693 NKYGPGEPSPVSETVVTPEAAPEKNPVDVKGEGNETTNMVI----------TWKPLRW-M 741
N YG +PS +S+ V T + P VD K E N V+ + + W +
Sbjct: 599 NAYGISDPSQISDPVKTQDVLPTSQGVDHKQVQRELGNAVLHLHNPTVLSSSSIEVHWTV 658
Query: 742 DWNAPQVQ-YRVQWRPQGT---RGPWQEQIVSDP---FLVVSNTSTFVPYEIKVQAVNSQ 794
D + +Q Y++ +RP G W V P +V+ + V YEIK + ++
Sbjct: 659 DQQSQYIQGYKILYRPSGANHGESDWLVFEVRTPAKNSVVIPDLRKGVNYEIKARPFFNE 718
Query: 795 GKGPEPQVTIGYSGEDYPQAIPELEGIEIL----NSSAVLVKWRPVDLAQVKGHLRGYNV 850
+G + ++ + E+ P A P +G+ + N +A+LV W+P G ++ Y V
Sbjct: 719 FQGADSEIKFAKTLEEAPSAPP--QGVTVSKNDGNGTAILVSWQPPPEDTQNGMVQEYKV 776
Query: 851 TYWREGSQRKHSKRHIHKDHVVVPANTTSVILSGLRPYSSYHLEVQAFNGRGSGPASE-- 908
W G++ ++ HI+K V +T SV++ L P Y +EV A G GSG SE
Sbjct: 777 --WCLGNETRY---HINK---TVDGSTFSVVIPFLVPGIRYSVEVAASTGAGSGVKSEPQ 828
Query: 909 FTFSTPEGVPGHPE 922
F G P PE
Sbjct: 829 FIQLDAHGNPVSPE 842
Score = 191 bits (486), Expect = 3e-48
Identities = 148/509 (29%), Positives = 227/509 (44%), Gaps = 35/509 (6%)
Query: 34 PPVITEQSPRRLVVFPTDDISLKCEASGKPEVQFRWTRDGVHFKPKEELGVTVYQSPHSG 93
PP I E P L+V + +L C+A G+P W + G + ++ + SG
Sbjct: 28 PPRIVEH-PSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRMLLPSG 86
Query: 94 S-FTITGNNSNFAQRFQGIYRCFASNKLGTAMSHEIRLMAEGAPKWPKETVKPVEVEEGE 152
S F + + ++ +G+Y C A N LG A+SH L ++ V V GE
Sbjct: 87 SLFFLRIVHGRKSRPDEGVYVCVARNYLGEAVSHNASLEVAILRDDFRQNPSDVMVAVGE 146
Query: 153 SVVLPCNPPPSAEPLRIYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYICHAH 212
V+ C PP I W +DER+T+ + G L SD Y+C
Sbjct: 147 PAVMECQPPRGHPEPTISWKKDGSPLDDKDERITI-RGGKLMITYTRKSDA-GKYVC--- 201
Query: 213 FPGTRTIIQKEP--IDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFP 270
GT + ++E +L V S + R L + S+ +C A G P
Sbjct: 202 -VGTNMVGERESEVAELTVLERPSFVKRPSNLAVTVDDSAEF----------KCEARGDP 250
Query: 271 TPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVTVE 330
PT++W + G +P R ++ + TL++ KV D G Y C+AEN +G A + +TV+
Sbjct: 251 VPTVRWRKDDGELPKSRYEIRDDH-TLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQ 309
Query: 331 AAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRING-----IPVEELAKDQKYRI- 384
P+++ KP+ + G T C+ G PQP + WR G + ++ +
Sbjct: 310 EPPHFVVKPRDQVVALGRTVTFQCEATGNPQPAIFWRREGSQNLLFSYQPPQSSSRFSVS 369
Query: 385 QRGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQL----PAKILTAD--NQTYMA 438
Q G L ++NVQ SD C+ N G ++ AY+ V + P ++ NQT +A
Sbjct: 370 QTGDLTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQGPVNQT-VA 428
Query: 439 VQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCL 498
V G T L C A G+PVP++ W + QD R NG L IR + DTGRY C+
Sbjct: 429 VDG-TFVLSCVATGSPVPTILWRKDGVLVSTQDSRIKQLENGVLQIRYAKLGDTGRYTCI 487
Query: 499 AANDQNNVTIMANLKVKDATQITQGPRST 527
A+ T A ++V++ Q PR T
Sbjct: 488 ASTPSGEATWSAYIEVQEFGVPVQPPRPT 516
Score = 174 bits (441), Expect = 5e-43
Identities = 201/825 (24%), Positives = 338/825 (40%), Gaps = 87/825 (10%)
Query: 237 DRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKT 296
D PR++ S L+ +G+P L C AEG PTPTI+W + + D+ ++H
Sbjct: 26 DFPPRIV---EHPSDLIVSKGEPATLNCKAEGRPTPTIEWYKGGERVETDKDDPRSHRML 82
Query: 297 LQ-----LLKV-----GEEDDGEYRCLAENSLGSARHAYYVTVEAAPY---WLHKPQSHL 343
L L++ D+G Y C+A N LG A ++ ++E A + P +
Sbjct: 83 LPSGSLFFLRIVHGRKSRPDEGVYVCVARNYLGEAV-SHNASLEVAILRDDFRQNPSDVM 141
Query: 344 YGPGETARLDCQV-QGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVT 402
GE A ++CQ +G P+P ++W+ +G P+++ KD++ I+ G L+++ + SD
Sbjct: 142 VAVGEPAVMECQPPRGHPEPTISWKKDGSPLDD--KDERITIRGGKLMITYTRKSDAGKY 199
Query: 403 QCEARNRHGLLLAN-AYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWL 461
C N G + A + V++ P+ + N +A C+A G PVP+V+W
Sbjct: 200 VCVGTNMVGERESEVAELTVLERPSFVKRPSNLAVTV--DDSAEFKCEARGDPVPTVRWR 257
Query: 462 DEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQIT 521
+DG L R+ + TL IR + A D G Y C+A N A L V++
Sbjct: 258 KDDGE--LPKSRYEIRDDHTLKIRKVTAGDMGSYTCVAENMVGKAEASATLTVQEPPHFV 315
Query: 522 QGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRD-----LQELGDSDKYFI-EDGR 575
PR + G VTF C+A+ +P QP+I WR +G Q S ++ + + G
Sbjct: 316 VKPRDQVVALGRTVTFQCEATGNP--QPAIFWRREGSQNLLFSYQPPQSSSRFSVSQTGD 373
Query: 576 LVIHSLDYSDQGNYSCVASTELDVVESRAQLLV----------VGSPGPVPRLVLSDLHL 625
L I ++ SD G Y C + ++A L V V GPV + V D
Sbjct: 374 LTITNVQRSDVGYYICQTLNVAGSIITKAYLEVTDVIADRPPPVIRQGPVNQTVAVDGTF 433
Query: 626 LTQSQVRVSWSPA---EDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPY 682
+ S P + D + E + K+ T + +P
Sbjct: 434 VLSCVATGSPVPTILWRKDGVLVSTQDSRIKQLENGVLQ-IRYAKLGDTGRYTCIASTPS 492
Query: 683 VHYTFRV-TAINKYG-PGEPSPVSETVVTPEAAPEKNPVDVKGEGNETTNMVITWKPLRW 740
T+ + ++G P +P ++ + P A + DV + ++W+P
Sbjct: 493 GEATWSAYIEVQEFGVPVQPPRPTDPNLIPSAPSKPEVTDVS-----RNTVTLSWQPN-- 545
Query: 741 MDWNAPQVQYRVQWRPQGTRGPWQE--QIVSDPFLVVSNTSTFVPYEIKVQAVNSQGKGP 798
++ A Y ++ + WQ + V + Y V+A N+ G
Sbjct: 546 LNSGATPTSYIIEAFSHASGSSWQTVAENVKTETSAIKGLKPNAIYLFLVRAANAYGISD 605
Query: 799 EPQVTIGYS---------GEDYPQ-------AIPELEGIEILNSSAVLVKWRPVDLAQVK 842
Q++ G D+ Q A+ L +L+SS++ V W + Q
Sbjct: 606 PSQISDPVKTQDVLPTSQGVDHKQVQRELGNAVLHLHNPTVLSSSSIEVHWT---VDQQS 662
Query: 843 GHLRGYNVTYWREGSQRKHSKRHIHKDHVVVPANTTSVILSGLRPYSSYHLEVQAFNGRG 902
+++GY + Y G+ S + + V PA SV++ LR +Y ++ + F
Sbjct: 663 QYIQGYKILYRPSGANHGESDWLVFE--VRTPAKN-SVVIPDLRKGVNYEIKARPFFNEF 719
Query: 903 SGPASEFTFS-TPEGVPGHPE---ALHLECQSNTSLLLRWQPPLSHNGVLTGYVLSYHPL 958
G SE F+ T E P P + + T++L+ WQPP G V Y
Sbjct: 720 QGADSEIKFAKTLEEAPSAPPQGVTVSKNDGNGTAILVSWQPP--PEDTQNGMVQEYKVW 777
Query: 959 DEGGKGQLSFNLR-DPELRTHNLTDLSPHLRYRFQLQATTKEGPG 1002
G + + N D + + L P +RY ++ A+T G G
Sbjct: 778 CLGNETRYHINKTVDGSTFSVVIPFLVPGIRYSVEVAASTGAGSG 822
>gi|193083163 roundabout, axon guidance receptor, homolog 2 isoform
ROBO2a [Homo sapiens]
Length = 1394
Score = 201 bits (511), Expect = 4e-51
Identities = 213/844 (25%), Positives = 339/844 (40%), Gaps = 87/844 (10%)
Query: 121 GTAMSHEIRLMAEGAPKWPKETVKPVEVEEGESVVLPCNPPPSAEPLRIYWMNSKILHIK 180
G RL E P E V V +GE L C P ++ + + +
Sbjct: 31 GNGQGQGSRLRQEDFPPRIVEHPSDVIVSKGEPTTLNCKAEGRPTPTIEWYKDGERVETD 90
Query: 181 QDERVT---MGQNGNLYFANVL----TSDNHSDYICHAHFPGTRTIIQKEPIDLRVKATN 233
+D+ + + +G+L+F ++ + + Y+C A + + +++ + +
Sbjct: 91 KDDPRSHRMLLPSGSLFFLRIVHGRRSKPDEGSYVCVARNYLGEAVSRNASLEVALLRDD 150
Query: 234 SMIDRKPRLLFPTNSSSHLVALQGQPLVLECIA-EGFPTPTIKWLRPSGPMPADRVTYQN 292
F N + +VA G+P +LEC G P PTI W + +
Sbjct: 151 ----------FRQNPTDVVVAA-GEPAILECQPPRGHPEPTIYWKKDKVRIDDKEERISI 199
Query: 293 HNKTLQLLKVGEEDDGEYRCLAENSLGSA-RHAYYVTVEAAPYWLHKPQSHLYGPGETAR 351
L + + D G Y C+ N +G +TV P +L +P + + E
Sbjct: 200 RGGKLMISNTRKSDAGMYTCVGTNMVGERDSDPAELTVFERPTFLRRPINQVVLEEEAVE 259
Query: 352 LDCQVQGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQCEARNRHG 411
CQVQG PQP V W+ + + D K L + +D C A NR G
Sbjct: 260 FRCQVQGDPQPTVRWKKDDADLPRGRYDIK---DDYTLRIKKTMSTDEGTYMCIAENRVG 316
Query: 412 LLLANAYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVL-- 469
+ A+A + V P ++ +Q + QG T C+ G P P+V W E +L
Sbjct: 317 KMEASATLTVRAPPQFVVRPRDQ--IVAQGRTVTFPCETKGNPQPAVFWQKEGSQNLLFP 374
Query: 470 -----QDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQ----- 519
+ R G L I ++Q +D G Y C A ++ A L+V D
Sbjct: 375 NQPQQPNSRCSVSPTGDLTITNIQRSDAGYYICQALTVAGSILAKAQLEVTDVLTDRPPP 434
Query: 520 -ITQGPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGRDLQELGDSDKYFIEDGRLVI 578
I QGP + C+A+ DP P I+W +G D E G L I
Sbjct: 435 IILQGPANQTLAVDGTALLKCKATGDPL--PVISWLKEGFTFPGR-DPRATIQEQGTLQI 491
Query: 579 HSLDYSDQGNYSCVASTE---------LDVVESRAQLL----VVGSPGPVPRLVLSDLHL 625
+L SD G Y+CVA++ LDV ES A + + PGP + ++D+
Sbjct: 492 KNLRISDTGTYTCVATSSSGETSWSAVLDVTESGATISKNYDLSDLPGPPSKPQVTDV-- 549
Query: 626 LTQSQVRVSWSPAEDHNAPIEKYDIEFEDKEMAPEKWYSLGKVPGNQTSTTLKLSPYVHY 685
T++ V +SW P P Y IE + ++ W ++ T L P Y
Sbjct: 550 -TKNSVTLSWQPGTPGTLPASAYIIEAFSQSVS-NSWQTVANHVKTTLYTVRGLRPNTIY 607
Query: 686 TFRVTAINKYGPGEPSPVSETVVTPEAAPEKNPVDVKGEGNETTNMVI----------TW 735
F V AIN G +PSP+S+ V T + +P VD + E ++++ T
Sbjct: 608 LFMVRAINPQGLSDPSPMSDPVRTQDISPPAQGVDHRQVQKELGDVLVRLHNPVVLTPTT 667
Query: 736 KPLRWMDWNAPQV--QYRVQWRPQG---TRGPWQE---QIVSDPFLVVSNTSTFVPYEIK 787
+ W PQ YRV +R WQ ++ ++ V+ N V YEIK
Sbjct: 668 VQVTWTVDRQPQFIQGYRVMYRQTSGLQATSSWQNLDAKVPTERSAVLVNLKKGVTYEIK 727
Query: 788 VQAVNSQGKGPEPQVTIGYSGEDYPQAIPE---LEGIEILNSSAVLVKWRPVDLAQVKGH 844
V+ ++ +G + + + E+ P A P+ + + NS+++ V W P G
Sbjct: 728 VRPYFNEFQGMDSESKTVRTTEEAPSAPPQSVTVLTVGSYNSTSISVSWDPPPPDHQNGI 787
Query: 845 LRGYNVTYWREGSQRKHSKRHIHKDHVVVPANTTSVILSGLRPYSSYHLEVQAFNGRGSG 904
++ Y + W G++ ++ HI+K V A SVI+ GL P Y +EV A G G
Sbjct: 788 IQEYKI--WCLGNE---TRFHINK---TVDAAIRSVIIGGLFPGIQYRVEVAASTSAGVG 839
Query: 905 PASE 908
SE
Sbjct: 840 VKSE 843
Score = 187 bits (476), Expect = 4e-47
Identities = 143/500 (28%), Positives = 228/500 (45%), Gaps = 37/500 (7%)
Query: 34 PPVITEQSPRRLVVFPTDDISLKCEASGKPEVQFRWTRDGVHFKPKEELGVTVYQSPHSG 93
PP I E P ++V + +L C+A G+P W +DG + ++ + SG
Sbjct: 46 PPRIVEH-PSDVIVSKGEPTTLNCKAEGRPTPTIEWYKDGERVETDKDDPRSHRMLLPSG 104
Query: 94 S-FTITGNNSNFAQRFQGIYRCFASNKLGTAMSH----EIRLMAEGAPKWPKETVKPVEV 148
S F + + ++ +G Y C A N LG A+S E+ L+ + + P + V V
Sbjct: 105 SLFFLRIVHGRRSKPDEGSYVCVARNYLGEAVSRNASLEVALLRDDFRQNPTDVV----V 160
Query: 149 EEGESVVLPCNPPPSAEPLRIYWMNSKILHIKQDERVTMGQNGNLYFANVLTSDNHSDYI 208
GE +L C PP IYW K+ ++ER+++ + G L +N SD
Sbjct: 161 AAGEPAILECQPPRGHPEPTIYWKKDKVRIDDKEERISI-RGGKLMISNTRKSDAGMYTC 219
Query: 209 CHAHFPGTRTIIQKEPIDLRVKATNSMIDRKPRLLFPTNSSSHLVALQGQPLVLECIAEG 268
+ G R +P +L V +R L P N V L+ + + C +G
Sbjct: 220 VGTNMVGER---DSDPAELTV------FERPTFLRRPINQ----VVLEEEAVEFRCQVQG 266
Query: 269 FPTPTIKWLRPSGPMPADRVTYQNHNKTLQLLKVGEEDDGEYRCLAENSLGSARHAYYVT 328
P PT++W + +P R ++ + TL++ K D+G Y C+AEN +G + +T
Sbjct: 267 DPQPTVRWKKDDADLPRGRYDIKD-DYTLRIKKTMSTDEGTYMCIAENRVGKMEASATLT 325
Query: 329 VEAAPYWLHKPQSHLYGPGETARLDCQVQGRPQPEVTWRING-----IPVEELAKDQKYR 383
V A P ++ +P+ + G T C+ +G PQP V W+ G P + + +
Sbjct: 326 VRAPPQFVVRPRDQIVAQGRTVTFPCETKGNPQPAVFWQKEGSQNLLFPNQPQQPNSRCS 385
Query: 384 IQ-RGALILSNVQPSDTMVTQCEARNRHGLLLANAYIYVVQL-----PAKILTADNQTYM 437
+ G L ++N+Q SD C+A G +LA A + V + P IL +
Sbjct: 386 VSPTGDLTITNIQRSDAGYYICQALTVAGSILAKAQLEVTDVLTDRPPPIILQGPANQTL 445
Query: 438 AVQGSTAYLLCKAFGAPVPSVQWLDEDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFC 497
AV G TA L CKA G P+P + WL E T +D R GTL I++L+ +DTG Y C
Sbjct: 446 AVDG-TALLKCKATGDPLPVISWLKEGFTFPGRDPRATIQEQGTLQIKNLRISDTGTYTC 504
Query: 498 LAANDQNNVTIMANLKVKDA 517
+A + + A L V ++
Sbjct: 505 VATSSSGETSWSAVLDVTES 524
Score = 163 bits (412), Expect = 1e-39
Identities = 204/839 (24%), Positives = 339/839 (40%), Gaps = 116/839 (13%)
Query: 237 DRKPRLLFPTNSSSHLVALQGQPLVLECIAEGFPTPTIKWLRPSGPMPADRVTYQNHNKT 296
D PR++ S ++ +G+P L C AEG PTPTI+W + + D+ ++H
Sbjct: 44 DFPPRIV---EHPSDVIVSKGEPTTLNCKAEGRPTPTIEWYKDGERVETDKDDPRSHRML 100
Query: 297 LQ-----LLKV-----GEEDDGEYRCLAENSLGSA--RHAYYVTVEAAPYWLHKPQSHLY 344
L L++ + D+G Y C+A N LG A R+A + P +
Sbjct: 101 LPSGSLFFLRIVHGRRSKPDEGSYVCVARNYLGEAVSRNASLEVALLRDDFRQNPTDVVV 160
Query: 345 GPGETARLDCQV-QGRPQPEVTWRINGIPVEELAKDQKYRIQRGALILSNVQPSDTMVTQ 403
GE A L+CQ +G P+P + W+ + + +++ K+++ I+ G L++SN + SD +
Sbjct: 161 AAGEPAILECQPPRGHPEPTIYWKKDKVRIDD--KEERISIRGGKLMISNTRKSDAGMYT 218
Query: 404 CEARNRHGLLLAN-AYIYVVQLPAKILTADNQTYMAVQGSTAYLLCKAFGAPVPSVQWLD 462
C N G ++ A + V + P + NQ + ++ C+ G P P+V+W
Sbjct: 219 CVGTNMVGERDSDPAELTVFERPTFLRRPINQ--VVLEEEAVEFRCQVQGDPQPTVRWKK 276
Query: 463 EDGTTVLQDERFFPYANGTLGIRDLQANDTGRYFCLAANDQNNVTIMANLKVKDATQITQ 522
+D L R+ + TL I+ + D G Y C+A N + A L V+ Q
Sbjct: 277 DDAD--LPRGRYDIKDDYTLRIKKTMSTDEGTYMCIAENRVGKMEASATLTVRAPPQFVV 334
Query: 523 GPRSTIEKKGSRVTFTCQASFDPSLQPSITWRGDGR------DLQELGDSDKYFIEDGRL 576
PR I +G VTF C+ +P QP++ W+ +G + + +S G L
Sbjct: 335 RPRDQIVAQGRTVTFPCETKGNP--QPAVFWQKEGSQNLLFPNQPQQPNSRCSVSPTGDL 392
Query: 577 VIHSLDYSDQGNYSCVASTELDVVESRAQLLVVGS----------PGPVPRLVLSDLHLL 626
I ++ SD G Y C A T + ++AQL V GP + + D L
Sbjct: 393 TITNIQRSDAGYYICQALTVAGSILAKAQLEVTDVLTDRPPPIILQGPANQTLAVDGTAL 452
Query: 627 TQSQVR------VSWS------PAEDHNAPI-EKYDIEFEDKEMAPEKWYSLGKVPGNQT 673
+ + +SW P D A I E+ ++ ++ ++ Y+ +
Sbjct: 453 LKCKATGDPLPVISWLKEGFTFPGRDPRATIQEQGTLQIKNLRISDTGTYTC---VATSS 509
Query: 674 STTLKLSPYVHYTFRVTAINKYG-----PGEPSPVSETVVTPEAAPEKNPVDVKGEGNET 728
S S + T I+K PG PS T VT KN V
Sbjct: 510 SGETSWSAVLDVTESGATISKNYDLSDLPGPPSKPQVTDVT------KNSV--------- 554
Query: 729 TNMVITWKPLRWMDWNAPQVQYRVQWRPQGTRGPWQEQI--VSDPFLVVSNTSTFVPYEI 786
++W+P P Y ++ Q WQ V V Y
Sbjct: 555 ---TLSWQP--GTPGTLPASAYIIEAFSQSVSNSWQTVANHVKTTLYTVRGLRPNTIYLF 609
Query: 787 KVQAVNSQG-KGPEPQ--------VTIGYSGEDYPQAIPELEGI-------EILNSSAVL 830
V+A+N QG P P ++ G D+ Q EL + +L + V
Sbjct: 610 MVRAINPQGLSDPSPMSDPVRTQDISPPAQGVDHRQVQKELGDVLVRLHNPVVLTPTTVQ 669
Query: 831 VKWRPVDLAQVKGHLRGYNVTYWR-EGSQRKHSKRHIHKDHVVVPANTTSVILSGLRPYS 889
V W Q ++GY V Y + G Q S +++ VP ++V+++ L+
Sbjct: 670 VTWTVDRQPQF---IQGYRVMYRQTSGLQATSSWQNLDAK---VPTERSAVLVN-LKKGV 722
Query: 890 SYHLEVQAFNGRGSGPASEF-TFSTPEGVPGHPE----ALHLECQSNTSLLLRWQPPLSH 944
+Y ++V+ + G SE T T E P P L + ++TS+ + W PP
Sbjct: 723 TYEIKVRPYFNEFQGMDSESKTVRTTEEAPSAPPQSVTVLTVGSYNSTSISVSWDPPPPD 782
Query: 945 NGVLTGYVLSYHPLDEGGKGQLSFNLR-DPELRTHNLTDLSPHLRYRFQLQATTKEGPG 1002
+ G + Y G + + N D +R+ + L P ++YR ++ A+T G G
Sbjct: 783 H--QNGIIQEYKIWCLGNETRFHINKTVDAAIRSVIIGGLFPGIQYRVEVAASTSAGVG 839
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.134 0.407
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 54,531,021
Number of Sequences: 37866
Number of extensions: 2755077
Number of successful extensions: 17183
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 271
Number of HSP's successfully gapped in prelim test: 222
Number of HSP's that attempted gapping in prelim test: 7364
Number of HSP's gapped (non-prelim): 4421
length of query: 1257
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1143
effective length of database: 13,930,794
effective search space: 15922897542
effective search space used: 15922897542
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.