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Search of human proteins with 4557439
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4557439 cyclin-dependent kinase 3 [Homo sapiens]
(305 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4557439 cyclin-dependent kinase 3 [Homo sapiens] 616 e-177
gi|16936528 cyclin-dependent kinase 2 isoform 1 [Homo sapiens] 467 e-132
gi|4502709 cell division cycle 2 isoform 1 [Homo sapiens] 399 e-111
gi|195927041 cell division cycle 2 isoform 3 [Homo sapiens] 397 e-111
gi|166362719 cyclin-dependent kinase 2 isoform 2 [Homo sapiens] 385 e-107
gi|4826675 cyclin-dependent kinase 5 [Homo sapiens] 362 e-100
gi|197333744 PCTAIRE protein kinase 1 isoform 2 [Homo sapiens] 326 2e-89
gi|5453860 PCTAIRE protein kinase 1 isoform 1 [Homo sapiens] 326 2e-89
gi|37595545 PCTAIRE protein kinase 2 [Homo sapiens] 325 3e-89
gi|47078233 PCTAIRE protein kinase 3 isoform a [Homo sapiens] 313 2e-85
gi|47078231 PCTAIRE protein kinase 3 isoform b [Homo sapiens] 313 2e-85
gi|47078229 PCTAIRE protein kinase 3 isoform b [Homo sapiens] 313 2e-85
gi|6912584 PFTAIRE protein kinase 1 [Homo sapiens] 299 2e-81
gi|21040235 PFTAIRE protein kinase 2 [Homo sapiens] 283 1e-76
gi|223718134 cyclin-dependent kinase 6 [Homo sapiens] 272 3e-73
gi|4502741 cyclin-dependent kinase 6 [Homo sapiens] 272 3e-73
gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isof... 271 4e-73
gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isof... 271 4e-73
gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isof... 271 4e-73
gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isof... 271 4e-73
gi|16332360 cell division cycle 2-like 1 (PITSLRE proteins) isof... 271 4e-73
gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isof... 271 4e-73
gi|4502743 cyclin-dependent kinase 7 [Homo sapiens] 271 7e-73
gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens] 270 1e-72
gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens] 270 1e-72
gi|89903018 cell cycle related kinase isoform 3 [Homo sapiens] 260 9e-70
gi|148596926 cyclin-dependent kinase 10 isoform a [Homo sapiens] 259 2e-69
gi|4502735 cyclin-dependent kinase 4 [Homo sapiens] 258 4e-69
gi|145309302 cell division cycle 2-like 5 isoform 1 [Homo sapiens] 243 2e-64
gi|145309300 cell division cycle 2-like 5 isoform 2 [Homo sapiens] 243 2e-64
>gi|4557439 cyclin-dependent kinase 3 [Homo sapiens]
Length = 305
Score = 616 bits (1589), Expect = e-177
Identities = 305/305 (100%), Positives = 305/305 (100%)
Query: 1 MDMFQKVEKIGEGTYGVVYKAKNRETGQLVALKKIRLDLEMEGVPSTAIREISLLKELKH 60
MDMFQKVEKIGEGTYGVVYKAKNRETGQLVALKKIRLDLEMEGVPSTAIREISLLKELKH
Sbjct: 1 MDMFQKVEKIGEGTYGVVYKAKNRETGQLVALKKIRLDLEMEGVPSTAIREISLLKELKH 60
Query: 61 PNIVRLLDVVHNERKLYLVFEFLSQDLKKYMDSTPGSELPLHLIKSYLFQLLQGVSFCHS 120
PNIVRLLDVVHNERKLYLVFEFLSQDLKKYMDSTPGSELPLHLIKSYLFQLLQGVSFCHS
Sbjct: 61 PNIVRLLDVVHNERKLYLVFEFLSQDLKKYMDSTPGSELPLHLIKSYLFQLLQGVSFCHS 120
Query: 121 HRVIHRDLKPQNLLINELGAIKLADFGLARAFGVPLRTYTHEVVTLWYRAPEILLGSKFY 180
HRVIHRDLKPQNLLINELGAIKLADFGLARAFGVPLRTYTHEVVTLWYRAPEILLGSKFY
Sbjct: 121 HRVIHRDLKPQNLLINELGAIKLADFGLARAFGVPLRTYTHEVVTLWYRAPEILLGSKFY 180
Query: 181 TTAVDIWSIGCIFAEMVTRKALFPGDSEIDQLFRIFRMLGTPSEDTWPGVTQLPDYKGSF 240
TTAVDIWSIGCIFAEMVTRKALFPGDSEIDQLFRIFRMLGTPSEDTWPGVTQLPDYKGSF
Sbjct: 181 TTAVDIWSIGCIFAEMVTRKALFPGDSEIDQLFRIFRMLGTPSEDTWPGVTQLPDYKGSF 240
Query: 241 PKWTRKGLEEIVPNLEPEGRDLLMQLLQYDPSQRITAKTALAHPYFSSPEPSPAARQYVL 300
PKWTRKGLEEIVPNLEPEGRDLLMQLLQYDPSQRITAKTALAHPYFSSPEPSPAARQYVL
Sbjct: 241 PKWTRKGLEEIVPNLEPEGRDLLMQLLQYDPSQRITAKTALAHPYFSSPEPSPAARQYVL 300
Query: 301 QRFRH 305
QRFRH
Sbjct: 301 QRFRH 305
>gi|16936528 cyclin-dependent kinase 2 isoform 1 [Homo sapiens]
Length = 298
Score = 467 bits (1202), Expect = e-132
Identities = 227/297 (76%), Positives = 259/297 (87%), Gaps = 1/297 (0%)
Query: 1 MDMFQKVEKIGEGTYGVVYKAKNRETGQLVALKKIRLDLEMEGVPSTAIREISLLKELKH 60
M+ FQKVEKIGEGTYGVVYKA+N+ TG++VALKKIRLD E EGVPSTAIREISLLKEL H
Sbjct: 1 MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNH 60
Query: 61 PNIVRLLDVVHNERKLYLVFEFLSQDLKKYMDSTPGSELPLHLIKSYLFQLLQGVSFCHS 120
PNIV+LLDV+H E KLYLVFEFL QDLKK+MD++ + +PL LIKSYLFQLLQG++FCHS
Sbjct: 61 PNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHS 120
Query: 121 HRVIHRDLKPQNLLINELGAIKLADFGLARAFGVPLRTYTHEVVTLWYRAPEILLGSKFY 180
HRV+HRDLKPQNLLIN GAIKLADFGLARAFGVP+RTYTHEVVTLWYRAPEILLG K+Y
Sbjct: 121 HRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYY 180
Query: 181 TTAVDIWSIGCIFAEMVTRKALFPGDSEIDQLFRIFRMLGTPSEDTWPGVTQLPDYKGSF 240
+TAVDIWS+GCIFAEMVTR+ALFPGDSEIDQLFRIFR LGTP E WPGVT +PDYK SF
Sbjct: 181 STAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSF 240
Query: 241 PKWTRKGLEEIVPNLEPEGRDLLMQLLQYDPSQRITAKTALAHPYFSS-PEPSPAAR 296
PKW R+ ++VP L+ +GR LL Q+L YDP++RI+AK ALAHP+F +P P R
Sbjct: 241 PKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLR 297
>gi|4502709 cell division cycle 2 isoform 1 [Homo sapiens]
Length = 297
Score = 399 bits (1024), Expect = e-111
Identities = 193/288 (67%), Positives = 233/288 (80%), Gaps = 1/288 (0%)
Query: 1 MDMFQKVEKIGEGTYGVVYKAKNRETGQLVALKKIRLDLEMEGVPSTAIREISLLKELKH 60
M+ + K+EKIGEGTYGVVYK +++ TGQ+VA+KKIRL+ E EGVPSTAIREISLLKEL+H
Sbjct: 1 MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRH 60
Query: 61 PNIVRLLDVVHNERKLYLVFEFLSQDLKKYMDSTP-GSELPLHLIKSYLFQLLQGVSFCH 119
PNIV L DV+ + +LYL+FEFLS DLKKY+DS P G + L+KSYL+Q+LQG+ FCH
Sbjct: 61 PNIVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFCH 120
Query: 120 SHRVIHRDLKPQNLLINELGAIKLADFGLARAFGVPLRTYTHEVVTLWYRAPEILLGSKF 179
S RV+HRDLKPQNLLI++ G IKLADFGLARAFG+P+R YTHEVVTLWYR+PE+LLGS
Sbjct: 121 SRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEVVTLWYRSPEVLLGSAR 180
Query: 180 YTTAVDIWSIGCIFAEMVTRKALFPGDSEIDQLFRIFRMLGTPSEDTWPGVTQLPDYKGS 239
Y+T VDIWSIG IFAE+ T+K LF GDSEIDQLFRIFR LGTP+ + WP V L DYK +
Sbjct: 181 YSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKNT 240
Query: 240 FPKWTRKGLEEIVPNLEPEGRDLLMQLLQYDPSQRITAKTALAHPYFS 287
FPKW L V NL+ G DLL ++L YDP++RI+ K AL HPYF+
Sbjct: 241 FPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFN 288
>gi|195927041 cell division cycle 2 isoform 3 [Homo sapiens]
Length = 297
Score = 397 bits (1019), Expect = e-111
Identities = 191/288 (66%), Positives = 232/288 (80%), Gaps = 1/288 (0%)
Query: 1 MDMFQKVEKIGEGTYGVVYKAKNRETGQLVALKKIRLDLEMEGVPSTAIREISLLKELKH 60
M+ + K+EKIGEGTYGVVYK +++ TGQ+VA+KKIRL+ E EGVPSTAIREISLLKEL+H
Sbjct: 1 MEDYTKIEKIGEGTYGVVYKGRHKTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELRH 60
Query: 61 PNIVRLLDVVHNERKLYLVFEFLSQDLKKYMDSTP-GSELPLHLIKSYLFQLLQGVSFCH 119
PNIV L DV+ + +LYL+FEFLS DLKKY+DS P G + L+KSYL+Q+LQG+ FCH
Sbjct: 61 PNIVSLQDVLMQDSRLYLIFEFLSMDLKKYLDSIPPGQYMDSSLVKSYLYQILQGIVFCH 120
Query: 120 SHRVIHRDLKPQNLLINELGAIKLADFGLARAFGVPLRTYTHEVVTLWYRAPEILLGSKF 179
S RV+HRDLKPQNLLI++ G IKLADFGLARAFG+P+R YTHE +TLWYR+PE+LLGS
Sbjct: 121 SRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEAITLWYRSPEVLLGSAR 180
Query: 180 YTTAVDIWSIGCIFAEMVTRKALFPGDSEIDQLFRIFRMLGTPSEDTWPGVTQLPDYKGS 239
Y+T VDIWSIG IFAE+ T+K LF GDSEIDQLFRIFR LGTP+ + WP V L DYK +
Sbjct: 181 YSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEVESLQDYKNT 240
Query: 240 FPKWTRKGLEEIVPNLEPEGRDLLMQLLQYDPSQRITAKTALAHPYFS 287
FPKW L V NL+ G DLL ++L YDP++RI+ K AL HPYF+
Sbjct: 241 FPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFN 288
>gi|166362719 cyclin-dependent kinase 2 isoform 2 [Homo sapiens]
Length = 264
Score = 385 bits (989), Expect = e-107
Identities = 197/297 (66%), Positives = 226/297 (76%), Gaps = 35/297 (11%)
Query: 1 MDMFQKVEKIGEGTYGVVYKAKNRETGQLVALKKIRLDLEMEGVPSTAIREISLLKELKH 60
M+ FQKVEKIGEGTYGVVYKA+N+ TG++VALKKIRLD E EGVPSTAIREISLLKEL H
Sbjct: 1 MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNH 60
Query: 61 PNIVRLLDVVHNERKLYLVFEFLSQDLKKYMDSTPGSELPLHLIKSYLFQLLQGVSFCHS 120
PNIV+LLDV+H E KLYLVFEFL QDLKK+MD++ + +PL LIKSYLFQLLQG++FCHS
Sbjct: 61 PNIVKLLDVIHTENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHS 120
Query: 121 HRVIHRDLKPQNLLINELGAIKLADFGLARAFGVPLRTYTHEVVTLWYRAPEILLGSKFY 180
HRV+HRDLKPQNLLIN GAIKLADFGLARAFGVP+RTYTHE
Sbjct: 121 HRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHE------------------ 162
Query: 181 TTAVDIWSIGCIFAEMVTRKALFPGDSEIDQLFRIFRMLGTPSEDTWPGVTQLPDYKGSF 240
VTR+ALFPGDSEIDQLFRIFR LGTP E WPGVT +PDYK SF
Sbjct: 163 ----------------VTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSF 206
Query: 241 PKWTRKGLEEIVPNLEPEGRDLLMQLLQYDPSQRITAKTALAHPYFSS-PEPSPAAR 296
PKW R+ ++VP L+ +GR LL Q+L YDP++RI+AK ALAHP+F +P P R
Sbjct: 207 PKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTKPVPHLR 263
>gi|4826675 cyclin-dependent kinase 5 [Homo sapiens]
Length = 292
Score = 362 bits (928), Expect = e-100
Identities = 179/289 (61%), Positives = 227/289 (78%), Gaps = 4/289 (1%)
Query: 1 MDMFQKVEKIGEGTYGVVYKAKNRETGQLVALKKIRLDLEMEGVPSTAIREISLLKELKH 60
M ++K+EKIGEGTYG V+KAKNRET ++VALK++RLD + EGVPS+A+REI LLKELKH
Sbjct: 1 MQKYEKLEKIGEGTYGTVFKAKNRETHEIVALKRVRLDDDDEGVPSSALREICLLKELKH 60
Query: 61 PNIVRLLDVVHNERKLYLVFEFLSQDLKKYMDSTPGSELPLHLIKSYLFQLLQGVSFCHS 120
NIVRL DV+H+++KL LVFEF QDLKKY DS G +L ++KS+LFQLL+G+ FCHS
Sbjct: 61 KNIVRLHDVLHSDKKLTLVFEFCDQDLKKYFDSCNG-DLDPEIVKSFLFQLLKGLGFCHS 119
Query: 121 HRVIHRDLKPQNLLINELGAIKLADFGLARAFGVPLRTYTHEVVTLWYRAPEILLGSKFY 180
V+HRDLKPQNLLIN G +KLADFGLARAFG+P+R Y+ EVVTLWYR P++L G+K Y
Sbjct: 120 RNVLHRDLKPQNLLINRNGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPDVLFGAKLY 179
Query: 181 TTAVDIWSIGCIFAEMVTR-KALFPGDSEIDQLFRIFRMLGTPSEDTWPGVTQLPDYKGS 239
+T++D+WS GCIFAE+ + LFPG+ DQL RIFR+LGTP+E+ WP +T+LPDYK
Sbjct: 180 STSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIFRLLGTPTEEQWPSMTKLPDYK-P 238
Query: 240 FPKW-TRKGLEEIVPNLEPEGRDLLMQLLQYDPSQRITAKTALAHPYFS 287
+P + L +VP L GRDLL LL+ +P QRI+A+ AL HPYFS
Sbjct: 239 YPMYPATTSLVNVVPKLNATGRDLLQNLLKCNPVQRISAEEALQHPYFS 287
>gi|197333744 PCTAIRE protein kinase 1 isoform 2 [Homo sapiens]
Length = 502
Score = 326 bits (835), Expect = 2e-89
Identities = 157/289 (54%), Positives = 219/289 (75%), Gaps = 3/289 (1%)
Query: 1 MDMFQKVEKIGEGTYGVVYKAKNRETGQLVALKKIRLDLEMEGVPSTAIREISLLKELKH 60
++ + K++K+GEGTY VYK K++ T LVALK+IRL+ E EG P TAIRE+SLLK+LKH
Sbjct: 168 LETYIKLDKLGEGTYATVYKGKSKLTDNLVALKEIRLEHE-EGAPCTAIREVSLLKDLKH 226
Query: 61 PNIVRLLDVVHNERKLYLVFEFLSQDLKKYMDSTPGSELPLHLIKSYLFQLLQGVSFCHS 120
NIV L D++H E+ L LVFE+L +DLK+Y+D G+ + +H +K +LFQLL+G+++CH
Sbjct: 227 ANIVTLHDIIHTEKSLTLVFEYLDKDLKQYLDDC-GNIINMHNVKLFLFQLLRGLAYCHR 285
Query: 121 HRVIHRDLKPQNLLINELGAIKLADFGLARAFGVPLRTYTHEVVTLWYRAPEILLGSKFY 180
+V+HRDLKPQNLLINE G +KLADFGLARA +P +TY++EVVTLWYR P+ILLGS Y
Sbjct: 286 QKVLHRDLKPQNLLINERGELKLADFGLARAKSIPTKTYSNEVVTLWYRPPDILLGSTDY 345
Query: 181 TTAVDIWSIGCIFAEMVTRKALFPGDSEIDQLFRIFRMLGTPSEDTWPGVTQLPDYKG-S 239
+T +D+W +GCIF EM T + LFPG + +QL IFR+LGTP+E+TWPG+ ++K +
Sbjct: 346 STQIDMWGVGCIFYEMATGRPLFPGSTVEEQLHFIFRILGTPTEETWPGILSNEEFKTYN 405
Query: 240 FPKWTRKGLEEIVPNLEPEGRDLLMQLLQYDPSQRITAKTALAHPYFSS 288
+PK+ + L P L+ +G DLL +LLQ++ RI+A+ A+ HP+F S
Sbjct: 406 YPKYRAEALLSHAPRLDSDGADLLTKLLQFEGRNRISAEDAMKHPFFLS 454
>gi|5453860 PCTAIRE protein kinase 1 isoform 1 [Homo sapiens]
Length = 496
Score = 326 bits (835), Expect = 2e-89
Identities = 157/289 (54%), Positives = 219/289 (75%), Gaps = 3/289 (1%)
Query: 1 MDMFQKVEKIGEGTYGVVYKAKNRETGQLVALKKIRLDLEMEGVPSTAIREISLLKELKH 60
++ + K++K+GEGTY VYK K++ T LVALK+IRL+ E EG P TAIRE+SLLK+LKH
Sbjct: 162 LETYIKLDKLGEGTYATVYKGKSKLTDNLVALKEIRLEHE-EGAPCTAIREVSLLKDLKH 220
Query: 61 PNIVRLLDVVHNERKLYLVFEFLSQDLKKYMDSTPGSELPLHLIKSYLFQLLQGVSFCHS 120
NIV L D++H E+ L LVFE+L +DLK+Y+D G+ + +H +K +LFQLL+G+++CH
Sbjct: 221 ANIVTLHDIIHTEKSLTLVFEYLDKDLKQYLDDC-GNIINMHNVKLFLFQLLRGLAYCHR 279
Query: 121 HRVIHRDLKPQNLLINELGAIKLADFGLARAFGVPLRTYTHEVVTLWYRAPEILLGSKFY 180
+V+HRDLKPQNLLINE G +KLADFGLARA +P +TY++EVVTLWYR P+ILLGS Y
Sbjct: 280 QKVLHRDLKPQNLLINERGELKLADFGLARAKSIPTKTYSNEVVTLWYRPPDILLGSTDY 339
Query: 181 TTAVDIWSIGCIFAEMVTRKALFPGDSEIDQLFRIFRMLGTPSEDTWPGVTQLPDYKG-S 239
+T +D+W +GCIF EM T + LFPG + +QL IFR+LGTP+E+TWPG+ ++K +
Sbjct: 340 STQIDMWGVGCIFYEMATGRPLFPGSTVEEQLHFIFRILGTPTEETWPGILSNEEFKTYN 399
Query: 240 FPKWTRKGLEEIVPNLEPEGRDLLMQLLQYDPSQRITAKTALAHPYFSS 288
+PK+ + L P L+ +G DLL +LLQ++ RI+A+ A+ HP+F S
Sbjct: 400 YPKYRAEALLSHAPRLDSDGADLLTKLLQFEGRNRISAEDAMKHPFFLS 448
>gi|37595545 PCTAIRE protein kinase 2 [Homo sapiens]
Length = 523
Score = 325 bits (833), Expect = 3e-89
Identities = 156/292 (53%), Positives = 220/292 (75%), Gaps = 3/292 (1%)
Query: 1 MDMFQKVEKIGEGTYGVVYKAKNRETGQLVALKKIRLDLEMEGVPSTAIREISLLKELKH 60
M+ + K+EK+GEGTY VYK +++ T LVALK+IRL+ E EG P TAIRE+SLLK+LKH
Sbjct: 189 METYIKLEKLGEGTYATVYKGRSKLTENLVALKEIRLEHE-EGAPCTAIREVSLLKDLKH 247
Query: 61 PNIVRLLDVVHNERKLYLVFEFLSQDLKKYMDSTPGSELPLHLIKSYLFQLLQGVSFCHS 120
NIV L D+VH ++ L LVFE+L +DLK+YMD G+ + +H +K +L+Q+L+G+++CH
Sbjct: 248 ANIVTLHDIVHTDKSLTLVFEYLDKDLKQYMDDC-GNIMSMHNVKLFLYQILRGLAYCHR 306
Query: 121 HRVIHRDLKPQNLLINELGAIKLADFGLARAFGVPLRTYTHEVVTLWYRAPEILLGSKFY 180
+V+HRDLKPQNLLINE G +KLADFGLARA VP +TY++EVVTLWYR P++LLGS Y
Sbjct: 307 RKVLHRDLKPQNLLINEKGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSSEY 366
Query: 181 TTAVDIWSIGCIFAEMVTRKALFPGDSEIDQLFRIFRMLGTPSEDTWPGVTQLPDYKG-S 239
+T +D+W +GCIF EM + + LFPG + D+L IFR+LGTPS++TWPG++ ++K +
Sbjct: 367 STQIDMWGVGCIFFEMASGRPLFPGSTVEDELHLIFRLLGTPSQETWPGISSNEEFKNYN 426
Query: 240 FPKWTRKGLEEIVPNLEPEGRDLLMQLLQYDPSQRITAKTALAHPYFSSPEP 291
FPK+ + L P L+ EG +L+ + LQY+ +R++A+ A+ H YF S P
Sbjct: 427 FPKYKPQPLINHAPRLDSEGIELITKFLQYESKKRVSAEEAMKHVYFRSLGP 478
>gi|47078233 PCTAIRE protein kinase 3 isoform a [Homo sapiens]
Length = 504
Score = 313 bits (801), Expect = 2e-85
Identities = 152/289 (52%), Positives = 213/289 (73%), Gaps = 3/289 (1%)
Query: 1 MDMFQKVEKIGEGTYGVVYKAKNRETGQLVALKKIRLDLEMEGVPSTAIREISLLKELKH 60
++ + K++K+GEGTY V+K +++ T LVALK+IRL+ E EG P TAIRE+SLLK LKH
Sbjct: 171 LETYVKLDKLGEGTYATVFKGRSKLTENLVALKEIRLEHE-EGAPCTAIREVSLLKNLKH 229
Query: 61 PNIVRLLDVVHNERKLYLVFEFLSQDLKKYMDSTPGSELPLHLIKSYLFQLLQGVSFCHS 120
NIV L D++H +R L LVFE+L DLK+Y+D G+ + +H +K ++FQLL+G+++CH
Sbjct: 230 ANIVTLHDLIHTDRSLTLVFEYLDSDLKQYLDHC-GNLMSMHNVKIFMFQLLRGLAYCHH 288
Query: 121 HRVIHRDLKPQNLLINELGAIKLADFGLARAFGVPLRTYTHEVVTLWYRAPEILLGSKFY 180
+++HRDLKPQNLLINE G +KLADFGLARA VP +TY++EVVTLWYR P++LLGS Y
Sbjct: 289 RKILHRDLKPQNLLINERGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTEY 348
Query: 181 TTAVDIWSIGCIFAEMVTRKALFPGDSEIDQLFRIFRMLGTPSEDTWPGVTQLPDYKG-S 239
+T +D+W +GCI EM T + LFPG + ++L IFR+LGTP+E+TWPGVT +++ S
Sbjct: 349 STPIDMWGVGCIHYEMATGRPLFPGSTVKEELHLIFRLLGTPTEETWPGVTAFSEFRTYS 408
Query: 240 FPKWTRKGLEEIVPNLEPEGRDLLMQLLQYDPSQRITAKTALAHPYFSS 288
FP + + L P L+ +G LL LL Y+ R++A+ AL+H YF S
Sbjct: 409 FPCYLPQPLINHAPRLDTDGIHLLSSLLLYESKSRMSAEAALSHSYFRS 457
>gi|47078231 PCTAIRE protein kinase 3 isoform b [Homo sapiens]
Length = 474
Score = 313 bits (801), Expect = 2e-85
Identities = 152/289 (52%), Positives = 213/289 (73%), Gaps = 3/289 (1%)
Query: 1 MDMFQKVEKIGEGTYGVVYKAKNRETGQLVALKKIRLDLEMEGVPSTAIREISLLKELKH 60
++ + K++K+GEGTY V+K +++ T LVALK+IRL+ E EG P TAIRE+SLLK LKH
Sbjct: 141 LETYVKLDKLGEGTYATVFKGRSKLTENLVALKEIRLEHE-EGAPCTAIREVSLLKNLKH 199
Query: 61 PNIVRLLDVVHNERKLYLVFEFLSQDLKKYMDSTPGSELPLHLIKSYLFQLLQGVSFCHS 120
NIV L D++H +R L LVFE+L DLK+Y+D G+ + +H +K ++FQLL+G+++CH
Sbjct: 200 ANIVTLHDLIHTDRSLTLVFEYLDSDLKQYLDHC-GNLMSMHNVKIFMFQLLRGLAYCHH 258
Query: 121 HRVIHRDLKPQNLLINELGAIKLADFGLARAFGVPLRTYTHEVVTLWYRAPEILLGSKFY 180
+++HRDLKPQNLLINE G +KLADFGLARA VP +TY++EVVTLWYR P++LLGS Y
Sbjct: 259 RKILHRDLKPQNLLINERGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTEY 318
Query: 181 TTAVDIWSIGCIFAEMVTRKALFPGDSEIDQLFRIFRMLGTPSEDTWPGVTQLPDYKG-S 239
+T +D+W +GCI EM T + LFPG + ++L IFR+LGTP+E+TWPGVT +++ S
Sbjct: 319 STPIDMWGVGCIHYEMATGRPLFPGSTVKEELHLIFRLLGTPTEETWPGVTAFSEFRTYS 378
Query: 240 FPKWTRKGLEEIVPNLEPEGRDLLMQLLQYDPSQRITAKTALAHPYFSS 288
FP + + L P L+ +G LL LL Y+ R++A+ AL+H YF S
Sbjct: 379 FPCYLPQPLINHAPRLDTDGIHLLSSLLLYESKSRMSAEAALSHSYFRS 427
>gi|47078229 PCTAIRE protein kinase 3 isoform b [Homo sapiens]
Length = 474
Score = 313 bits (801), Expect = 2e-85
Identities = 152/289 (52%), Positives = 213/289 (73%), Gaps = 3/289 (1%)
Query: 1 MDMFQKVEKIGEGTYGVVYKAKNRETGQLVALKKIRLDLEMEGVPSTAIREISLLKELKH 60
++ + K++K+GEGTY V+K +++ T LVALK+IRL+ E EG P TAIRE+SLLK LKH
Sbjct: 141 LETYVKLDKLGEGTYATVFKGRSKLTENLVALKEIRLEHE-EGAPCTAIREVSLLKNLKH 199
Query: 61 PNIVRLLDVVHNERKLYLVFEFLSQDLKKYMDSTPGSELPLHLIKSYLFQLLQGVSFCHS 120
NIV L D++H +R L LVFE+L DLK+Y+D G+ + +H +K ++FQLL+G+++CH
Sbjct: 200 ANIVTLHDLIHTDRSLTLVFEYLDSDLKQYLDHC-GNLMSMHNVKIFMFQLLRGLAYCHH 258
Query: 121 HRVIHRDLKPQNLLINELGAIKLADFGLARAFGVPLRTYTHEVVTLWYRAPEILLGSKFY 180
+++HRDLKPQNLLINE G +KLADFGLARA VP +TY++EVVTLWYR P++LLGS Y
Sbjct: 259 RKILHRDLKPQNLLINERGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPDVLLGSTEY 318
Query: 181 TTAVDIWSIGCIFAEMVTRKALFPGDSEIDQLFRIFRMLGTPSEDTWPGVTQLPDYKG-S 239
+T +D+W +GCI EM T + LFPG + ++L IFR+LGTP+E+TWPGVT +++ S
Sbjct: 319 STPIDMWGVGCIHYEMATGRPLFPGSTVKEELHLIFRLLGTPTEETWPGVTAFSEFRTYS 378
Query: 240 FPKWTRKGLEEIVPNLEPEGRDLLMQLLQYDPSQRITAKTALAHPYFSS 288
FP + + L P L+ +G LL LL Y+ R++A+ AL+H YF S
Sbjct: 379 FPCYLPQPLINHAPRLDTDGIHLLSSLLLYESKSRMSAEAALSHSYFRS 427
>gi|6912584 PFTAIRE protein kinase 1 [Homo sapiens]
Length = 451
Score = 299 bits (766), Expect = 2e-81
Identities = 158/294 (53%), Positives = 204/294 (69%), Gaps = 6/294 (2%)
Query: 2 DMFQKVEKIGEGTYGVVYKAKNRETGQLVALKKIRLDLEMEGVPSTAIREISLLKELKHP 61
D ++K+EK+GEG+Y VYK K++ G+LVALK IRL E EG P TAIRE SLLK LKH
Sbjct: 115 DSYEKLEKLGEGSYATVYKGKSKVNGKLVALKVIRLQ-EEEGTPFTAIREASLLKGLKHA 173
Query: 62 NIVRLLDVVHNERKLYLVFEFLSQDLKKYMDSTPGSELPLHLIKSYLFQLLQGVSFCHSH 121
NIV L D++H + L LVFE++ DL +YMD PG P + +K +LFQLL+G+S+ H
Sbjct: 174 NIVLLHDIIHTKETLTLVFEYVHTDLCQYMDKHPGGLHPDN-VKLFLFQLLRGLSYIHQR 232
Query: 122 RVIHRDLKPQNLLINELGAIKLADFGLARAFGVPLRTYTHEVVTLWYRAPEILLGSKFYT 181
++HRDLKPQNLLI++ G +KLADFGLARA VP TY++EVVTLWYR P++LLGS Y+
Sbjct: 233 YILHRDLKPQNLLISDTGELKLADFGLARAKSVPSHTYSNEVVTLWYRPPDVLLGSTEYS 292
Query: 182 TAVDIWSIGCIFAEMVTRKALFPGDSEI-DQLFRIFRMLGTPSEDTWPGVTQLPDYKGS- 239
T +D+W +GCIF EM+ A FPG +I DQL RIF +LGTP+EDTWPGV LP +K
Sbjct: 293 TCLDMWGVGCIFVEMIQGVAAFPGMKDIQDQLERIFLVLGTPNEDTWPGVHSLPHFKPER 352
Query: 240 FPKWTRKGLEEIVPNLE--PEGRDLLMQLLQYDPSQRITAKTALAHPYFSSPEP 291
F ++ K L + L DL +LLQ P R++A+ AL+H YFS P
Sbjct: 353 FTLYSSKNLRQAWNKLSYVNHAEDLASKLLQCSPKNRLSAQAALSHEYFSDLPP 406
>gi|21040235 PFTAIRE protein kinase 2 [Homo sapiens]
Length = 384
Score = 283 bits (725), Expect = 1e-76
Identities = 150/289 (51%), Positives = 199/289 (68%), Gaps = 6/289 (2%)
Query: 4 FQKVEKIGEGTYGVVYKAKNRETGQLVALKKIRLDLEMEGVPSTAIREISLLKELKHPNI 63
+ +EK+GEG+Y VYK +R GQLVALK I ++ E EGVP TAIRE SLLK LKH NI
Sbjct: 52 YLNLEKLGEGSYATVYKGISRINGQLVALKVISMNAE-EGVPFTAIREASLLKGLKHANI 110
Query: 64 VRLLDVVHNERKLYLVFEFLSQDLKKYMDSTPGSELPLHLIKSYLFQLLQGVSFCHSHRV 123
V L D++H + L VFE++ DL +YM PG P H ++ ++FQLL+G+++ H V
Sbjct: 111 VLLHDIIHTKETLTFVFEYMHTDLAQYMSQHPGGLHP-HNVRLFMFQLLRGLAYIHHQHV 169
Query: 124 IHRDLKPQNLLINELGAIKLADFGLARAFGVPLRTYTHEVVTLWYRAPEILLGSKFYTTA 183
+HRDLKPQNLLI+ LG +KLADFGLARA +P +TY+ EVVTLWYR P+ LLG+ Y++
Sbjct: 170 LHRDLKPQNLLISHLGELKLADFGLARAKSIPSQTYSSEVVTLWYRPPDALLGATEYSSE 229
Query: 184 VDIWSIGCIFAEMVTRKALFPGDSEI-DQLFRIFRMLGTPSEDTWPGVTQLPDYKGS-FP 241
+DIW GCIF EM + LFPG S I +QL +I+ +LG P+EDTWPGV++LP+Y FP
Sbjct: 230 LDIWGAGCIFIEMFQGQPLFPGVSNILEQLEKIWEVLGVPTEDTWPGVSKLPNYNPEWFP 289
Query: 242 KWTRKGLEEIVPNL--EPEGRDLLMQLLQYDPSQRITAKTALAHPYFSS 288
T + L + L PE DL Q+L+ P R++A+ AL H YFS+
Sbjct: 290 LPTPRSLHVVWNRLGRVPEAEDLASQMLKGFPRDRVSAQEALVHDYFSA 338
>gi|223718134 cyclin-dependent kinase 6 [Homo sapiens]
Length = 326
Score = 272 bits (695), Expect = 3e-73
Identities = 142/296 (47%), Positives = 200/296 (67%), Gaps = 13/296 (4%)
Query: 4 FQKVEKIGEGTYGVVYKAKN-RETGQLVALKKIRLDLEMEGVPSTAIREISLLKELK--- 59
++ V +IGEG YG V+KA++ + G+ VALK++R+ EG+P + IRE+++L+ L+
Sbjct: 13 YECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEGMPLSTIREVAVLRHLETFE 72
Query: 60 HPNIVRLLDV-----VHNERKLYLVFEFLSQDLKKYMDSTPGSELPLHLIKSYLFQLLQG 114
HPN+VRL DV E KL LVFE + QDL Y+D P +P IK +FQLL+G
Sbjct: 73 HPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPEPGVPTETIKDMMFQLLRG 132
Query: 115 VSFCHSHRVIHRDLKPQNLLINELGAIKLADFGLARAFGVPLRTYTHEVVTLWYRAPEIL 174
+ F HSHRV+HRDLKPQN+L+ G IKLADFGLAR + + T VVTLWYRAPE+L
Sbjct: 133 LDFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLARIYSFQM-ALTSVVVTLWYRAPEVL 191
Query: 175 LGSKFYTTAVDIWSIGCIFAEMVTRKALFPGDSEIDQLFRIFRMLGTPSEDTWPGVTQLP 234
L S Y T VD+WS+GCIFAEM RK LF G S++DQL +I ++G P E+ WP LP
Sbjct: 192 LQSS-YATPVDLWSVGCIFAEMFRRKPLFRGSSDVDQLGKILDVIGLPGEEDWPRDVALP 250
Query: 235 DYKGSFPKWTRKGLEEIVPNLEPEGRDLLMQLLQYDPSQRITAKTALAHPYFSSPE 290
+ +F + + +E+ V +++ G+DLL++ L ++P++RI+A +AL+HPYF E
Sbjct: 251 --RQAFHSKSAQPIEKFVTDIDELGKDLLLKCLTFNPAKRISAYSALSHPYFQDLE 304
>gi|4502741 cyclin-dependent kinase 6 [Homo sapiens]
Length = 326
Score = 272 bits (695), Expect = 3e-73
Identities = 142/296 (47%), Positives = 200/296 (67%), Gaps = 13/296 (4%)
Query: 4 FQKVEKIGEGTYGVVYKAKN-RETGQLVALKKIRLDLEMEGVPSTAIREISLLKELK--- 59
++ V +IGEG YG V+KA++ + G+ VALK++R+ EG+P + IRE+++L+ L+
Sbjct: 13 YECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEGMPLSTIREVAVLRHLETFE 72
Query: 60 HPNIVRLLDV-----VHNERKLYLVFEFLSQDLKKYMDSTPGSELPLHLIKSYLFQLLQG 114
HPN+VRL DV E KL LVFE + QDL Y+D P +P IK +FQLL+G
Sbjct: 73 HPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPEPGVPTETIKDMMFQLLRG 132
Query: 115 VSFCHSHRVIHRDLKPQNLLINELGAIKLADFGLARAFGVPLRTYTHEVVTLWYRAPEIL 174
+ F HSHRV+HRDLKPQN+L+ G IKLADFGLAR + + T VVTLWYRAPE+L
Sbjct: 133 LDFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLARIYSFQM-ALTSVVVTLWYRAPEVL 191
Query: 175 LGSKFYTTAVDIWSIGCIFAEMVTRKALFPGDSEIDQLFRIFRMLGTPSEDTWPGVTQLP 234
L S Y T VD+WS+GCIFAEM RK LF G S++DQL +I ++G P E+ WP LP
Sbjct: 192 LQSS-YATPVDLWSVGCIFAEMFRRKPLFRGSSDVDQLGKILDVIGLPGEEDWPRDVALP 250
Query: 235 DYKGSFPKWTRKGLEEIVPNLEPEGRDLLMQLLQYDPSQRITAKTALAHPYFSSPE 290
+ +F + + +E+ V +++ G+DLL++ L ++P++RI+A +AL+HPYF E
Sbjct: 251 --RQAFHSKSAQPIEKFVTDIDELGKDLLLKCLTFNPAKRISAYSALSHPYFQDLE 304
>gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isoform
9 [Homo sapiens]
Length = 771
Score = 271 bits (694), Expect = 4e-73
Identities = 136/290 (46%), Positives = 202/290 (69%), Gaps = 5/290 (1%)
Query: 1 MDMFQKVEKIGEGTYGVVYKAKNRETGQLVALKKIRLDLEMEGVPSTAIREISLLKELKH 60
++ FQ + +I EGTYGVVY+AK+++T ++VALK+++++ E EG P T++REI+ + + +H
Sbjct: 411 VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQH 470
Query: 61 PNIVRLLDVV--HNERKLYLVFEFLSQDLKKYMDSTPGSELPLHLIKSYLFQLLQGVSFC 118
PNIV + ++V N K+Y+V ++ DLK M++ LP +K+ + QLL+GV
Sbjct: 471 PNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGE-VKTLMIQLLRGVKHL 529
Query: 119 HSHRVIHRDLKPQNLLINELGAIKLADFGLARAFGVPLRTYTHEVVTLWYRAPEILLGSK 178
H + ++HRDLK NLL++ G +K+ DFGLAR +G PL+ YT VVTLWYRAPE+LLG+K
Sbjct: 530 HDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAK 589
Query: 179 FYTTAVDIWSIGCIFAEMVTRKALFPGDSEIDQLFRIFRMLGTPSEDTWPGVTQLPDYKG 238
Y+TAVD+WS+GCIF E++T+K LFPG SEIDQ+ ++F+ LGTPSE WPG ++LP K
Sbjct: 590 EYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKK 649
Query: 239 -SFPKWTRKGL-EEIVPNLEPEGRDLLMQLLQYDPSQRITAKTALAHPYF 286
+F + L + L +G DL+ + L Y P +RI+A+ L H YF
Sbjct: 650 MTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYF 699
>gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isoform
8 [Homo sapiens]
Length = 780
Score = 271 bits (694), Expect = 4e-73
Identities = 136/290 (46%), Positives = 202/290 (69%), Gaps = 5/290 (1%)
Query: 1 MDMFQKVEKIGEGTYGVVYKAKNRETGQLVALKKIRLDLEMEGVPSTAIREISLLKELKH 60
++ FQ + +I EGTYGVVY+AK+++T ++VALK+++++ E EG P T++REI+ + + +H
Sbjct: 420 VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQH 479
Query: 61 PNIVRLLDVV--HNERKLYLVFEFLSQDLKKYMDSTPGSELPLHLIKSYLFQLLQGVSFC 118
PNIV + ++V N K+Y+V ++ DLK M++ LP +K+ + QLL+GV
Sbjct: 480 PNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGE-VKTLMIQLLRGVKHL 538
Query: 119 HSHRVIHRDLKPQNLLINELGAIKLADFGLARAFGVPLRTYTHEVVTLWYRAPEILLGSK 178
H + ++HRDLK NLL++ G +K+ DFGLAR +G PL+ YT VVTLWYRAPE+LLG+K
Sbjct: 539 HDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAK 598
Query: 179 FYTTAVDIWSIGCIFAEMVTRKALFPGDSEIDQLFRIFRMLGTPSEDTWPGVTQLPDYKG 238
Y+TAVD+WS+GCIF E++T+K LFPG SEIDQ+ ++F+ LGTPSE WPG ++LP K
Sbjct: 599 EYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKK 658
Query: 239 -SFPKWTRKGL-EEIVPNLEPEGRDLLMQLLQYDPSQRITAKTALAHPYF 286
+F + L + L +G DL+ + L Y P +RI+A+ L H YF
Sbjct: 659 MTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYF 708
>gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isoform
5 [Homo sapiens]
Length = 748
Score = 271 bits (694), Expect = 4e-73
Identities = 136/290 (46%), Positives = 202/290 (69%), Gaps = 5/290 (1%)
Query: 1 MDMFQKVEKIGEGTYGVVYKAKNRETGQLVALKKIRLDLEMEGVPSTAIREISLLKELKH 60
++ FQ + +I EGTYGVVY+AK+++T ++VALK+++++ E EG P T++REI+ + + +H
Sbjct: 388 VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQH 447
Query: 61 PNIVRLLDVV--HNERKLYLVFEFLSQDLKKYMDSTPGSELPLHLIKSYLFQLLQGVSFC 118
PNIV + ++V N K+Y+V ++ DLK M++ LP +K+ + QLL+GV
Sbjct: 448 PNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGE-VKTLMIQLLRGVKHL 506
Query: 119 HSHRVIHRDLKPQNLLINELGAIKLADFGLARAFGVPLRTYTHEVVTLWYRAPEILLGSK 178
H + ++HRDLK NLL++ G +K+ DFGLAR +G PL+ YT VVTLWYRAPE+LLG+K
Sbjct: 507 HDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAK 566
Query: 179 FYTTAVDIWSIGCIFAEMVTRKALFPGDSEIDQLFRIFRMLGTPSEDTWPGVTQLPDYKG 238
Y+TAVD+WS+GCIF E++T+K LFPG SEIDQ+ ++F+ LGTPSE WPG ++LP K
Sbjct: 567 EYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKK 626
Query: 239 -SFPKWTRKGL-EEIVPNLEPEGRDLLMQLLQYDPSQRITAKTALAHPYF 286
+F + L + L +G DL+ + L Y P +RI+A+ L H YF
Sbjct: 627 MTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYF 676
>gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isoform
4 [Homo sapiens]
Length = 737
Score = 271 bits (694), Expect = 4e-73
Identities = 136/290 (46%), Positives = 202/290 (69%), Gaps = 5/290 (1%)
Query: 1 MDMFQKVEKIGEGTYGVVYKAKNRETGQLVALKKIRLDLEMEGVPSTAIREISLLKELKH 60
++ FQ + +I EGTYGVVY+AK+++T ++VALK+++++ E EG P T++REI+ + + +H
Sbjct: 377 VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQH 436
Query: 61 PNIVRLLDVV--HNERKLYLVFEFLSQDLKKYMDSTPGSELPLHLIKSYLFQLLQGVSFC 118
PNIV + ++V N K+Y+V ++ DLK M++ LP +K+ + QLL+GV
Sbjct: 437 PNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGE-VKTLMIQLLRGVKHL 495
Query: 119 HSHRVIHRDLKPQNLLINELGAIKLADFGLARAFGVPLRTYTHEVVTLWYRAPEILLGSK 178
H + ++HRDLK NLL++ G +K+ DFGLAR +G PL+ YT VVTLWYRAPE+LLG+K
Sbjct: 496 HDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAK 555
Query: 179 FYTTAVDIWSIGCIFAEMVTRKALFPGDSEIDQLFRIFRMLGTPSEDTWPGVTQLPDYKG 238
Y+TAVD+WS+GCIF E++T+K LFPG SEIDQ+ ++F+ LGTPSE WPG ++LP K
Sbjct: 556 EYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKK 615
Query: 239 -SFPKWTRKGL-EEIVPNLEPEGRDLLMQLLQYDPSQRITAKTALAHPYF 286
+F + L + L +G DL+ + L Y P +RI+A+ L H YF
Sbjct: 616 MTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYF 665
>gi|16332360 cell division cycle 2-like 1 (PITSLRE proteins) isoform
3 [Homo sapiens]
Length = 526
Score = 271 bits (694), Expect = 4e-73
Identities = 136/290 (46%), Positives = 202/290 (69%), Gaps = 5/290 (1%)
Query: 1 MDMFQKVEKIGEGTYGVVYKAKNRETGQLVALKKIRLDLEMEGVPSTAIREISLLKELKH 60
++ FQ + +I EGTYGVVY+AK+++T ++VALK+++++ E EG P T++REI+ + + +H
Sbjct: 166 VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQH 225
Query: 61 PNIVRLLDVV--HNERKLYLVFEFLSQDLKKYMDSTPGSELPLHLIKSYLFQLLQGVSFC 118
PNIV + ++V N K+Y+V ++ DLK M++ LP +K+ + QLL+GV
Sbjct: 226 PNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGE-VKTLMIQLLRGVKHL 284
Query: 119 HSHRVIHRDLKPQNLLINELGAIKLADFGLARAFGVPLRTYTHEVVTLWYRAPEILLGSK 178
H + ++HRDLK NLL++ G +K+ DFGLAR +G PL+ YT VVTLWYRAPE+LLG+K
Sbjct: 285 HDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAK 344
Query: 179 FYTTAVDIWSIGCIFAEMVTRKALFPGDSEIDQLFRIFRMLGTPSEDTWPGVTQLPDYKG 238
Y+TAVD+WS+GCIF E++T+K LFPG SEIDQ+ ++F+ LGTPSE WPG ++LP K
Sbjct: 345 EYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKK 404
Query: 239 -SFPKWTRKGL-EEIVPNLEPEGRDLLMQLLQYDPSQRITAKTALAHPYF 286
+F + L + L +G DL+ + L Y P +RI+A+ L H YF
Sbjct: 405 MTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYF 454
>gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isoform
2 [Homo sapiens]
Length = 782
Score = 271 bits (694), Expect = 4e-73
Identities = 136/290 (46%), Positives = 202/290 (69%), Gaps = 5/290 (1%)
Query: 1 MDMFQKVEKIGEGTYGVVYKAKNRETGQLVALKKIRLDLEMEGVPSTAIREISLLKELKH 60
++ FQ + +I EGTYGVVY+AK+++T ++VALK+++++ E EG P T++REI+ + + +H
Sbjct: 422 VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQH 481
Query: 61 PNIVRLLDVV--HNERKLYLVFEFLSQDLKKYMDSTPGSELPLHLIKSYLFQLLQGVSFC 118
PNIV + ++V N K+Y+V ++ DLK M++ LP +K+ + QLL+GV
Sbjct: 482 PNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGE-VKTLMIQLLRGVKHL 540
Query: 119 HSHRVIHRDLKPQNLLINELGAIKLADFGLARAFGVPLRTYTHEVVTLWYRAPEILLGSK 178
H + ++HRDLK NLL++ G +K+ DFGLAR +G PL+ YT VVTLWYRAPE+LLG+K
Sbjct: 541 HDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWYRAPELLLGAK 600
Query: 179 FYTTAVDIWSIGCIFAEMVTRKALFPGDSEIDQLFRIFRMLGTPSEDTWPGVTQLPDYKG 238
Y+TAVD+WS+GCIF E++T+K LFPG SEIDQ+ ++F+ LGTPSE WPG ++LP K
Sbjct: 601 EYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWPGYSELPAVKK 660
Query: 239 -SFPKWTRKGL-EEIVPNLEPEGRDLLMQLLQYDPSQRITAKTALAHPYF 286
+F + L + L +G DL+ + L Y P +RI+A+ L H YF
Sbjct: 661 MTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYF 710
>gi|4502743 cyclin-dependent kinase 7 [Homo sapiens]
Length = 346
Score = 271 bits (692), Expect = 7e-73
Identities = 137/297 (46%), Positives = 194/297 (65%), Gaps = 6/297 (2%)
Query: 4 FQKVEKIGEGTYGVVYKAKNRETGQLVALKKIRLDLEME---GVPSTAIREISLLKELKH 60
++K++ +GEG + VYKA+++ T Q+VA+KKI+L E G+ TA+REI LL+EL H
Sbjct: 12 YEKLDFLGEGQFATVYKARDKNTNQIVAIKKIKLGHRSEAKDGINRTALREIKLLQELSH 71
Query: 61 PNIVRLLDVVHNERKLYLVFEFLSQDLKKYMDSTPGSELPLHLIKSYLFQLLQGVSFCHS 120
PNI+ LLD ++ + LVF+F+ DL+ + P H IK+Y+ LQG+ + H
Sbjct: 72 PNIIGLLDAFGHKSNISLVFDFMETDLEVIIKDNSLVLTPSH-IKAYMLMTLQGLEYLHQ 130
Query: 121 HRVIHRDLKPQNLLINELGAIKLADFGLARAFGVPLRTYTHEVVTLWYRAPEILLGSKFY 180
H ++HRDLKP NLL++E G +KLADFGLA++FG P R YTH+VVT WYRAPE+L G++ Y
Sbjct: 131 HWILHRDLKPNNLLLDENGVLKLADFGLAKSFGSPNRAYTHQVVTRWYRAPELLFGARMY 190
Query: 181 TTAVDIWSIGCIFAEMVTRKALFPGDSEIDQLFRIFRMLGTPSEDTWPGVTQLPDYKGSF 240
VD+W++GCI AE++ R PGDS++DQL RIF LGTP+E+ WP + LPDY +F
Sbjct: 191 GVGVDMWAVGCILAELLLRVPFLPGDSDLDQLTRIFETLGTPTEEQWPDMCSLPDYV-TF 249
Query: 241 PKWTRKGLEEIVPNLEPEGRDLLMQLLQYDPSQRITAKTALAHPYFSS-PEPSPAAR 296
+ L I + DL+ L ++P RITA AL YFS+ P P+P +
Sbjct: 250 KSFPGIPLHHIFSAAGDDLLDLIQGLFLFNPCARITATQALKMKYFSNRPGPTPGCQ 306
>gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens]
Length = 770
Score = 270 bits (690), Expect = 1e-72
Identities = 135/290 (46%), Positives = 202/290 (69%), Gaps = 5/290 (1%)
Query: 1 MDMFQKVEKIGEGTYGVVYKAKNRETGQLVALKKIRLDLEMEGVPSTAIREISLLKELKH 60
++ FQ + +I EGTYGVVY+AK+++T ++VALK+++++ E EG P T++REI+ + + +H
Sbjct: 410 VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQH 469
Query: 61 PNIVRLLDVV--HNERKLYLVFEFLSQDLKKYMDSTPGSELPLHLIKSYLFQLLQGVSFC 118
PNIV + ++V N K+Y+V ++ DLK M++ LP +K+ + QLL+GV
Sbjct: 470 PNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGE-VKTLMIQLLRGVKHL 528
Query: 119 HSHRVIHRDLKPQNLLINELGAIKLADFGLARAFGVPLRTYTHEVVTLWYRAPEILLGSK 178
H + ++HRDLK NLL++ G +K+ DFGLAR +G PL+ YT VVT WYRAPE+LLG+K
Sbjct: 529 HDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAK 588
Query: 179 FYTTAVDIWSIGCIFAEMVTRKALFPGDSEIDQLFRIFRMLGTPSEDTWPGVTQLPDYKG 238
Y+TAVD+WS+GCIF E++T+K LFPG+SEIDQ+ ++F+ LGTPSE WPG ++LP K
Sbjct: 589 EYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKK 648
Query: 239 -SFPKWTRKGL-EEIVPNLEPEGRDLLMQLLQYDPSQRITAKTALAHPYF 286
+F + L + L +G DL+ + L Y P +RI+A+ L H YF
Sbjct: 649 MTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYF 698
>gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens]
Length = 780
Score = 270 bits (690), Expect = 1e-72
Identities = 135/290 (46%), Positives = 202/290 (69%), Gaps = 5/290 (1%)
Query: 1 MDMFQKVEKIGEGTYGVVYKAKNRETGQLVALKKIRLDLEMEGVPSTAIREISLLKELKH 60
++ FQ + +I EGTYGVVY+AK+++T ++VALK+++++ E EG P T++REI+ + + +H
Sbjct: 420 VEEFQCLNRIEEGTYGVVYRAKDKKTDEIVALKRLKMEKEKEGFPITSLREINTILKAQH 479
Query: 61 PNIVRLLDVV--HNERKLYLVFEFLSQDLKKYMDSTPGSELPLHLIKSYLFQLLQGVSFC 118
PNIV + ++V N K+Y+V ++ DLK M++ LP +K+ + QLL+GV
Sbjct: 480 PNIVTVREIVVGSNMDKIYIVMNYVEHDLKSLMETMKQPFLPGE-VKTLMIQLLRGVKHL 538
Query: 119 HSHRVIHRDLKPQNLLINELGAIKLADFGLARAFGVPLRTYTHEVVTLWYRAPEILLGSK 178
H + ++HRDLK NLL++ G +K+ DFGLAR +G PL+ YT VVT WYRAPE+LLG+K
Sbjct: 539 HDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWYRAPELLLGAK 598
Query: 179 FYTTAVDIWSIGCIFAEMVTRKALFPGDSEIDQLFRIFRMLGTPSEDTWPGVTQLPDYKG 238
Y+TAVD+WS+GCIF E++T+K LFPG+SEIDQ+ ++F+ LGTPSE WPG ++LP K
Sbjct: 599 EYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWPGYSELPVVKK 658
Query: 239 -SFPKWTRKGL-EEIVPNLEPEGRDLLMQLLQYDPSQRITAKTALAHPYF 286
+F + L + L +G DL+ + L Y P +RI+A+ L H YF
Sbjct: 659 MTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYF 708
>gi|89903018 cell cycle related kinase isoform 3 [Homo sapiens]
Length = 346
Score = 260 bits (665), Expect = 9e-70
Identities = 139/306 (45%), Positives = 199/306 (65%), Gaps = 5/306 (1%)
Query: 1 MDMFQKVEKIGEGTYGVVYKAKNRETGQLVALKKIRLDLEMEGVPSTAIREISLLKELK- 59
MD + + +IGEG +G+V+KAK+ ETG++VALKK+ L +G P+ A+REI L+E++
Sbjct: 1 MDQYCILGRIGEGAHGIVFKAKHVETGEIVALKKVALRRLEDGFPNQALREIKALQEMED 60
Query: 60 HPNIVRLLDVVHNERKLYLVFEFLSQDLKKYMDSTPGSELPLHLIKSYLFQLLQGVSFCH 119
+ +V+L V + L FEF+ DL + + L +KSYL LL+GV+FCH
Sbjct: 61 NQYVVQLKAVFPHGGGFVLAFEFMLSDLAEVVRHAQ-RPLAQAQVKSYLQMLLKGVAFCH 119
Query: 120 SHRVIHRDLKPQNLLINELGAIKLADFGLARAFGVP-LRTYTHEVVTLWYRAPEILLGSK 178
++ ++HRDLKP NLLI+ G +K+ADFGLAR F R YTH+V T WYRAPE+L G++
Sbjct: 120 ANNIVHRDLKPANLLISASGQLKIADFGLARVFSPDGSRLYTHQVATRWYRAPELLYGAR 179
Query: 179 FYTTAVDIWSIGCIFAEMVTRKALFPGDSEIDQLFRIFRMLGTPSEDTWPGVTQLPDY-K 237
Y VD+WS+GCI E++ LFPG ++I+QL + R+LGTP+ WP +T+LPDY K
Sbjct: 180 QYDQGVDLWSVGCIMGELLNGSPLFPGKNDIEQLCYVLRILGTPNPQVWPELTELPDYNK 239
Query: 238 GSFPKWTRKGLEEIVPNLEPEGRDLLMQLLQYDPSQRITAKTALAHPY-FSSPEPSPAAR 296
SF + LEE++P++ P+ DLL Q L Y P QRI A AL H Y F++P P+ +
Sbjct: 240 ISFKEQVPMPLEEVLPDVSPQALDLLGQFLLYPPHQRIAASKALLHQYFFTAPLPAHPSE 299
Query: 297 QYVLQR 302
+ QR
Sbjct: 300 LPIPQR 305
>gi|148596926 cyclin-dependent kinase 10 isoform a [Homo sapiens]
Length = 360
Score = 259 bits (662), Expect = 2e-69
Identities = 135/295 (45%), Positives = 198/295 (67%), Gaps = 9/295 (3%)
Query: 4 FQKVEKIGEGTYGVVYKAKNRETGQLVALKKIRLDLEMEGVPSTAIREISLLKELKHPNI 63
F+K+ +IGEGTYG+VY+A++ +T ++VALKK+R+D E +G+P +++REI+LL L+HPNI
Sbjct: 39 FEKLNRIGEGTYGIVYRARDTQTDEIVALKKVRMDKEKDGIPISSLREITLLLRLRHPNI 98
Query: 64 VRLLDVV--HNERKLYLVFEFLSQDLKKYMDS--TPGSELPLHLIKSYLFQLLQGVSFCH 119
V L +VV ++ ++LV + QDL +++ TP SE +K + Q+L+G+ + H
Sbjct: 99 VELKEVVVGNHLESIFLVMGYCEQDLASLLENMPTPFSEAQ---VKCIVLQVLRGLQYLH 155
Query: 120 SHRVIHRDLKPQNLLINELGAIKLADFGLARAFGVPLRTYTHEVVTLWYRAPEILLGSKF 179
+ +IHRDLK NLL+ + G +K ADFGLARA+GVP++ T +VVTLWYRAPE+LLG+
Sbjct: 156 RNFIIHRDLKVSNLLMTDKGCVKTADFGLARAYGVPVKPMTPKVVTLWYRAPELLLGTTT 215
Query: 180 YTTAVDIWSIGCIFAEMVTRKALFPGDSEIDQLFRIFRMLGTPSEDTWPGVTQLPDY-KG 238
TT++D+W++GCI AE++ + L PG SEI Q+ I ++LGTPSE+ WPG ++LP +
Sbjct: 216 QTTSIDMWAVGCILAELLAHRPLLPGTSEIHQIDLIVQLLGTPSENIWPGFSKLPLVGQY 275
Query: 239 SFPKWTRKGLEEIVPNLEPEGRDLLMQLLQYDPSQRITAKTALAHPYFSSPEPSP 293
S K L+ P L G LL L YDP +R TA L YF +P P
Sbjct: 276 SLRKQPYNNLKHKFPWLSEAGLRLLHFLFMYDPKKRATAGDCLESSYFKE-KPLP 329
>gi|4502735 cyclin-dependent kinase 4 [Homo sapiens]
Length = 303
Score = 258 bits (660), Expect = 4e-69
Identities = 137/301 (45%), Positives = 193/301 (64%), Gaps = 15/301 (4%)
Query: 4 FQKVEKIGEGTYGVVYKAKNRETGQLVALKKIRLDLEMEG---VPSTAIREISLLKELK- 59
++ V +IG G YG VYKA++ +G VALK +R+ G +P + +RE++LL+ L+
Sbjct: 6 YEPVAEIGVGAYGTVYKARDPHSGHFVALKSVRVPNGGGGGGGLPISTVREVALLRRLEA 65
Query: 60 --HPNIVRLLDVVHNER-----KLYLVFEFLSQDLKKYMDSTPGSELPLHLIKSYLFQLL 112
HPN+VRL+DV R K+ LVFE + QDL+ Y+D P LP IK + Q L
Sbjct: 66 FEHPNVVRLMDVCATSRTDREIKVTLVFEHVDQDLRTYLDKAPPPGLPAETIKDLMRQFL 125
Query: 113 QGVSFCHSHRVIHRDLKPQNLLINELGAIKLADFGLARAFGVPLRTYTHEVVTLWYRAPE 172
+G+ F H++ ++HRDLKP+N+L+ G +KLADFGLAR + + T VVTLWYRAPE
Sbjct: 126 RGLDFLHANCIVHRDLKPENILVTSGGTVKLADFGLARIYSYQM-ALTPVVVTLWYRAPE 184
Query: 173 ILLGSKFYTTAVDIWSIGCIFAEMVTRKALFPGDSEIDQLFRIFRMLGTPSEDTWPGVTQ 232
+LL S Y T VD+WS+GCIFAEM RK LF G+SE DQL +IF ++G P ED WP
Sbjct: 185 VLLQST-YATPVDMWSVGCIFAEMFRRKPLFCGNSEADQLGKIFDLIGLPPEDDWPRDVS 243
Query: 233 LPDYKGSFPKWTRKGLEEIVPNLEPEGRDLLMQLLQYDPSQRITAKTALAHPYFSSPEPS 292
LP +G+FP + ++ +VP +E G LL+++L ++P +RI+A AL H Y E +
Sbjct: 244 LP--RGAFPPRGPRPVQSVVPEMEESGAQLLLEMLTFNPHKRISAFRALQHSYLHKDEGN 301
Query: 293 P 293
P
Sbjct: 302 P 302
>gi|145309302 cell division cycle 2-like 5 isoform 1 [Homo sapiens]
Length = 1512
Score = 243 bits (619), Expect = 2e-64
Identities = 133/305 (43%), Positives = 189/305 (61%), Gaps = 15/305 (4%)
Query: 1 MDMFQKVEKIGEGTYGVVYKAKNRETGQLVALKKIRLDLEMEGVPSTAIREISLLKELKH 60
+D F + IGEGTYG VYKA++++TG++VALKK+RLD E EG P TAIREI +L++L H
Sbjct: 702 VDKFDIIGIIGEGTYGQVYKARDKDTGEMVALKKVRLDNEKEGFPITAIREIKILRQLTH 761
Query: 61 PNIVRLLDVVHNERK----------LYLVFEFLSQDLKKYMDSTPGSELPLHLIKSYLFQ 110
+I+ + ++V ++ YLVFE++ DL ++S H IKS++ Q
Sbjct: 762 QSIINMKEIVTDKEDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFNENH-IKSFMRQ 820
Query: 111 LLQGVSFCHSHRVIHRDLKPQNLLINELGAIKLADFGLARAFGVP-LRTYTHEVVTLWYR 169
L++G+ +CH +HRD+K N+L+N G IKLADFGLAR + R YT++V+TLWYR
Sbjct: 821 LMEGLDYCHKKNFLHRDIKCSNILLNNRGQIKLADFGLARLYSSEESRPYTNKVITLWYR 880
Query: 170 APEILLGSKFYTTAVDIWSIGCIFAEMVTRKALFPGDSEIDQLFRIFRMLGTPSEDTWPG 229
PE+LLG + YT A+D+WS GCI E+ T+K +F + E+ QL I R+ G+P WP
Sbjct: 881 PPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANQELAQLELISRICGSPCPAVWPD 940
Query: 230 VTQLPDYKGSFPK--WTRKGLEEIVPNLEPEGRDLLMQLLQYDPSQRITAKTALAHPYFS 287
V +LP + PK + RK EE V + DL +L DPS+R TA+ AL +
Sbjct: 941 VIKLPYFNTMKPKKQYRRKLREEFV-FIPAAALDLFDYMLALDPSKRCTAEQALQCEFLR 999
Query: 288 SPEPS 292
EPS
Sbjct: 1000 DVEPS 1004
>gi|145309300 cell division cycle 2-like 5 isoform 2 [Homo sapiens]
Length = 1452
Score = 243 bits (619), Expect = 2e-64
Identities = 133/305 (43%), Positives = 189/305 (61%), Gaps = 15/305 (4%)
Query: 1 MDMFQKVEKIGEGTYGVVYKAKNRETGQLVALKKIRLDLEMEGVPSTAIREISLLKELKH 60
+D F + IGEGTYG VYKA++++TG++VALKK+RLD E EG P TAIREI +L++L H
Sbjct: 702 VDKFDIIGIIGEGTYGQVYKARDKDTGEMVALKKVRLDNEKEGFPITAIREIKILRQLTH 761
Query: 61 PNIVRLLDVVHNERK----------LYLVFEFLSQDLKKYMDSTPGSELPLHLIKSYLFQ 110
+I+ + ++V ++ YLVFE++ DL ++S H IKS++ Q
Sbjct: 762 QSIINMKEIVTDKEDALDFKKDKGAFYLVFEYMDHDLMGLLESGLVHFNENH-IKSFMRQ 820
Query: 111 LLQGVSFCHSHRVIHRDLKPQNLLINELGAIKLADFGLARAFGVP-LRTYTHEVVTLWYR 169
L++G+ +CH +HRD+K N+L+N G IKLADFGLAR + R YT++V+TLWYR
Sbjct: 821 LMEGLDYCHKKNFLHRDIKCSNILLNNRGQIKLADFGLARLYSSEESRPYTNKVITLWYR 880
Query: 170 APEILLGSKFYTTAVDIWSIGCIFAEMVTRKALFPGDSEIDQLFRIFRMLGTPSEDTWPG 229
PE+LLG + YT A+D+WS GCI E+ T+K +F + E+ QL I R+ G+P WP
Sbjct: 881 PPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANQELAQLELISRICGSPCPAVWPD 940
Query: 230 VTQLPDYKGSFPK--WTRKGLEEIVPNLEPEGRDLLMQLLQYDPSQRITAKTALAHPYFS 287
V +LP + PK + RK EE V + DL +L DPS+R TA+ AL +
Sbjct: 941 VIKLPYFNTMKPKKQYRRKLREEFV-FIPAAALDLFDYMLALDPSKRCTAEQALQCEFLR 999
Query: 288 SPEPS 292
EPS
Sbjct: 1000 DVEPS 1004
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.139 0.418
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,878,287
Number of Sequences: 37866
Number of extensions: 557910
Number of successful extensions: 3842
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 744
Number of HSP's successfully gapped in prelim test: 56
Number of HSP's that attempted gapping in prelim test: 1211
Number of HSP's gapped (non-prelim): 994
length of query: 305
length of database: 18,247,518
effective HSP length: 102
effective length of query: 203
effective length of database: 14,385,186
effective search space: 2920192758
effective search space used: 2920192758
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.