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Search of human proteins with 4557431
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4557431 T-cell receptor zeta chain isoform 2 precursor [Homo
sapiens]
(163 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4557431 T-cell receptor zeta chain isoform 2 precursor [Homo ... 332 1e-91
gi|37595565 T-cell receptor zeta chain isoform 1 precursor [Homo... 327 3e-90
gi|4758344 Fc fragment of IgE, high affinity I, receptor for, ga... 54 5e-08
gi|24308215 retrotransposon gag domain containing 1 [Homo sapiens] 30 0.92
gi|76881819 sterile alpha motif domain containing 11 [Homo sapiens] 30 0.92
gi|91208430 CD86 antigen isoform 1 [Homo sapiens] 28 2.7
gi|21450838 SH3 and cysteine rich domain 3 [Homo sapiens] 28 2.7
gi|145312241 differentially expressed in FDCP 6 homolog [Homo sa... 28 3.5
gi|213972593 TPTE and PTEN homologous inositol lipid phosphatase... 28 3.5
gi|213972591 TPTE and PTEN homologous inositol lipid phosphatase... 28 3.5
gi|213972589 TPTE and PTEN homologous inositol lipid phosphatase... 28 3.5
gi|40549435 transmembrane phosphatase with tensin homology isofo... 28 4.6
gi|40549433 transmembrane phosphatase with tensin homology isofo... 28 4.6
gi|109689707 transmembrane phosphatase with tensin homology isof... 28 4.6
gi|8923516 ankyrin repeat and SOCS box-containing 6 isoform 1 [H... 28 4.6
gi|30089932 ankyrin repeat and SOCS box-containing 6 isoform 2 [... 28 4.6
gi|239756473 PREDICTED: transmembrane protein 114 [Homo sapiens] 27 6.0
gi|239752599 PREDICTED: transmembrane protein 114, partial [Homo... 27 6.0
gi|239745400 PREDICTED: transmembrane protein 114 [Homo sapiens] 27 6.0
gi|40806170 spastin isoform 2 [Homo sapiens] 27 6.0
gi|11875211 spastin isoform 1 [Homo sapiens] 27 6.0
gi|34878777 ring finger protein 20 [Homo sapiens] 27 6.0
gi|226437592 transmembrane protein 114 [Homo sapiens] 27 6.0
gi|119120903 par-3 partitioning defective 3 homolog B isoform c ... 27 6.0
gi|119120897 par-3 partitioning defective 3 homolog B isoform b ... 27 6.0
gi|11386179 guanine nucleotide binding protein (G protein), gamm... 27 7.8
>gi|4557431 T-cell receptor zeta chain isoform 2 precursor [Homo
sapiens]
Length = 163
Score = 332 bits (850), Expect = 1e-91
Identities = 163/163 (100%), Positives = 163/163 (100%)
Query: 1 MKWKALFTAAILQAQLPITEAQSFGLLDPKLCYLLDGILFIYGVILTALFLRVKFSRSAD 60
MKWKALFTAAILQAQLPITEAQSFGLLDPKLCYLLDGILFIYGVILTALFLRVKFSRSAD
Sbjct: 1 MKWKALFTAAILQAQLPITEAQSFGLLDPKLCYLLDGILFIYGVILTALFLRVKFSRSAD 60
Query: 61 APAYQQGQNQLYNELNLGRREEYDVLDKRRGRDPEMGGKPRRKNPQEGLYNELQKDKMAE 120
APAYQQGQNQLYNELNLGRREEYDVLDKRRGRDPEMGGKPRRKNPQEGLYNELQKDKMAE
Sbjct: 61 APAYQQGQNQLYNELNLGRREEYDVLDKRRGRDPEMGGKPRRKNPQEGLYNELQKDKMAE 120
Query: 121 AYSEIGMKGERRRGKGHDGLYQGLSTATKDTYDALHMQALPPR 163
AYSEIGMKGERRRGKGHDGLYQGLSTATKDTYDALHMQALPPR
Sbjct: 121 AYSEIGMKGERRRGKGHDGLYQGLSTATKDTYDALHMQALPPR 163
>gi|37595565 T-cell receptor zeta chain isoform 1 precursor [Homo
sapiens]
Length = 164
Score = 327 bits (838), Expect = 3e-90
Identities = 163/164 (99%), Positives = 163/164 (99%), Gaps = 1/164 (0%)
Query: 1 MKWKALFTAAILQAQLPITEAQSFGLLDPKLCYLLDGILFIYGVILTALFLRVKFSRSAD 60
MKWKALFTAAILQAQLPITEAQSFGLLDPKLCYLLDGILFIYGVILTALFLRVKFSRSAD
Sbjct: 1 MKWKALFTAAILQAQLPITEAQSFGLLDPKLCYLLDGILFIYGVILTALFLRVKFSRSAD 60
Query: 61 APAYQQGQNQLYNELNLGRREEYDVLDKRRGRDPEMGGKP-RRKNPQEGLYNELQKDKMA 119
APAYQQGQNQLYNELNLGRREEYDVLDKRRGRDPEMGGKP RRKNPQEGLYNELQKDKMA
Sbjct: 61 APAYQQGQNQLYNELNLGRREEYDVLDKRRGRDPEMGGKPQRRKNPQEGLYNELQKDKMA 120
Query: 120 EAYSEIGMKGERRRGKGHDGLYQGLSTATKDTYDALHMQALPPR 163
EAYSEIGMKGERRRGKGHDGLYQGLSTATKDTYDALHMQALPPR
Sbjct: 121 EAYSEIGMKGERRRGKGHDGLYQGLSTATKDTYDALHMQALPPR 164
>gi|4758344 Fc fragment of IgE, high affinity I, receptor for,
gamma polypeptide precursor [Homo sapiens]
Length = 86
Score = 54.3 bits (129), Expect = 5e-08
Identities = 29/82 (35%), Positives = 49/82 (59%), Gaps = 4/82 (4%)
Query: 6 LFTAAILQAQLPITEAQSFGLLDPKLCYLLDGILFIYGVILTALFLRVKFS-RSADAPAY 64
+ A +L L + +A + G +P+LCY+LD ILF+YG++LT L+ R+K R A +Y
Sbjct: 1 MIPAVVLLLLLLVEQAAALG--EPQLCYILDAILFLYGIVLTLLYCRLKIQVRKAAITSY 58
Query: 65 QQGQNQLYNELNLGRREEYDVL 86
++ +Y L+ +E Y+ L
Sbjct: 59 EKSDG-VYTGLSTRNQETYETL 79
Score = 27.7 bits (60), Expect = 4.6
Identities = 11/24 (45%), Positives = 16/24 (66%)
Query: 138 DGLYQGLSTATKDTYDALHMQALP 161
DG+Y GLST ++TY+ L + P
Sbjct: 62 DGVYTGLSTRNQETYETLKHEKPP 85
>gi|24308215 retrotransposon gag domain containing 1 [Homo sapiens]
Length = 1388
Score = 30.0 bits (66), Expect = 0.92
Identities = 13/23 (56%), Positives = 16/23 (69%)
Query: 14 AQLPITEAQSFGLLDPKLCYLLD 36
A+ P E SFG+L P LCYLL+
Sbjct: 1131 AKPPPKEVPSFGMLTPALCYLLE 1153
>gi|76881819 sterile alpha motif domain containing 11 [Homo sapiens]
Length = 681
Score = 30.0 bits (66), Expect = 0.92
Identities = 22/70 (31%), Positives = 29/70 (41%), Gaps = 6/70 (8%)
Query: 46 LTALFLRVKFSRSADAPAYQQGQNQLYNELNLGRREEYDVLDKRRGRDPEMGG------K 99
L L V SR P +Q L +G R D+L KR GR P + +
Sbjct: 107 LPTLISSVHRSRHLVMPEHQSRCEFQRGSLEIGLRPAGDLLGKRLGRSPRISSDCFSEKR 166
Query: 100 PRRKNPQEGL 109
R ++PQE L
Sbjct: 167 ARSESPQEAL 176
>gi|91208430 CD86 antigen isoform 1 [Homo sapiens]
Length = 329
Score = 28.5 bits (62), Expect = 2.7
Identities = 22/85 (25%), Positives = 37/85 (43%), Gaps = 19/85 (22%)
Query: 27 LDPKLCYLLDGILFIYGVILTA---LFLRVKFSRSADAPA----------------YQQG 67
+DP+ L ILF+ +L+ L ++ F+ +AD P +Q
Sbjct: 1 MDPQCTMGLSNILFVMAFLLSGAAPLKIQAYFNETADLPCQFANSQNQSLSELVVFWQDQ 60
Query: 68 QNQLYNELNLGRREEYDVLDKRRGR 92
+N + NE+ LG+ + V K GR
Sbjct: 61 ENLVLNEVYLGKEKFDSVHSKYMGR 85
>gi|21450838 SH3 and cysteine rich domain 3 [Homo sapiens]
Length = 364
Score = 28.5 bits (62), Expect = 2.7
Identities = 27/104 (25%), Positives = 38/104 (36%), Gaps = 8/104 (7%)
Query: 55 FSRSADAPAYQQGQNQLYNELNLGRREEYDVLDKRRGRDPEMGGKPRRKNPQEGLYNELQ 114
F R+ +P Y Q +L+ R + R G M K R+K + +
Sbjct: 148 FHRAYSSPLYSNQQYACVKDLSAANRNDPVFETLRTG--VIMANKERKKGQAD------K 199
Query: 115 KDKMAEAYSEIGMKGERRRGKGHDGLYQGLSTATKDTYDALHMQ 158
K+ +A E GK DG +G A K T D H Q
Sbjct: 200 KNPVAAMMEEEPESARPEEGKPQDGNPEGDKKAEKKTPDDKHKQ 243
>gi|145312241 differentially expressed in FDCP 6 homolog [Homo
sapiens]
Length = 631
Score = 28.1 bits (61), Expect = 3.5
Identities = 22/91 (24%), Positives = 44/91 (48%), Gaps = 2/91 (2%)
Query: 66 QGQNQLYNELNLGRREEYDVLDKRR-GRDPEMGGKPRRKNPQEGLYNELQKDKMAEAYSE 124
+G+ L+ +L RRE+ + ++RR ++ E+ + + +E EL+ + A+ +E
Sbjct: 316 EGKTSLHKDLKQKRREQREQRERRRAAKEEELLRLQQLQEEKERKLQELELLQEAQRQAE 375
Query: 125 -IGMKGERRRGKGHDGLYQGLSTATKDTYDA 154
+ + E RR H L Q L ++ A
Sbjct: 376 RLLQEEEERRRSQHRELQQALEGQLREAEQA 406
>gi|213972593 TPTE and PTEN homologous inositol lipid phosphatase
isoform delta [Homo sapiens]
Length = 411
Score = 28.1 bits (61), Expect = 3.5
Identities = 15/42 (35%), Positives = 20/42 (47%), Gaps = 7/42 (16%)
Query: 129 GERRRGKGHDGLYQGLSTATKDTYDALHMQA-------LPPR 163
GERR K H +QG+ T +++ Y Q LPPR
Sbjct: 241 GERRTNKTHSNKFQGVETPSQNRYVGYFAQVKHLYNWNLPPR 282
>gi|213972591 TPTE and PTEN homologous inositol lipid phosphatase
isoform gamma [Homo sapiens]
Length = 522
Score = 28.1 bits (61), Expect = 3.5
Identities = 15/42 (35%), Positives = 20/42 (47%), Gaps = 7/42 (16%)
Query: 129 GERRRGKGHDGLYQGLSTATKDTYDALHMQA-------LPPR 163
GERR K H +QG+ T +++ Y Q LPPR
Sbjct: 352 GERRTNKTHSNKFQGVETPSQNRYVGYFAQVKHLYNWNLPPR 393
>gi|213972589 TPTE and PTEN homologous inositol lipid phosphatase
isoform alpha [Homo sapiens]
Length = 445
Score = 28.1 bits (61), Expect = 3.5
Identities = 15/42 (35%), Positives = 20/42 (47%), Gaps = 7/42 (16%)
Query: 129 GERRRGKGHDGLYQGLSTATKDTYDALHMQA-------LPPR 163
GERR K H +QG+ T +++ Y Q LPPR
Sbjct: 275 GERRTNKTHSNKFQGVETPSQNRYVGYFAQVKHLYNWNLPPR 316
>gi|40549435 transmembrane phosphatase with tensin homology isoform
gamma [Homo sapiens]
Length = 513
Score = 27.7 bits (60), Expect = 4.6
Identities = 16/42 (38%), Positives = 20/42 (47%), Gaps = 7/42 (16%)
Query: 129 GERRRGKGHDGLYQGLSTATKDTYDALHMQA-------LPPR 163
GERR K H +QG+ T ++ Y A Q LPPR
Sbjct: 332 GERRTDKTHSEKFQGVETPSQKRYVAYFAQVKHLYNWNLPPR 373
>gi|40549433 transmembrane phosphatase with tensin homology isoform
beta [Homo sapiens]
Length = 533
Score = 27.7 bits (60), Expect = 4.6
Identities = 16/42 (38%), Positives = 20/42 (47%), Gaps = 7/42 (16%)
Query: 129 GERRRGKGHDGLYQGLSTATKDTYDALHMQA-------LPPR 163
GERR K H +QG+ T ++ Y A Q LPPR
Sbjct: 352 GERRTDKTHSEKFQGVETPSQKRYVAYFAQVKHLYNWNLPPR 393
>gi|109689707 transmembrane phosphatase with tensin homology isoform
alpha [Homo sapiens]
Length = 551
Score = 27.7 bits (60), Expect = 4.6
Identities = 16/42 (38%), Positives = 20/42 (47%), Gaps = 7/42 (16%)
Query: 129 GERRRGKGHDGLYQGLSTATKDTYDALHMQA-------LPPR 163
GERR K H +QG+ T ++ Y A Q LPPR
Sbjct: 370 GERRTDKTHSEKFQGVETPSQKRYVAYFAQVKHLYNWNLPPR 411
>gi|8923516 ankyrin repeat and SOCS box-containing 6 isoform 1
[Homo sapiens]
Length = 421
Score = 27.7 bits (60), Expect = 4.6
Identities = 21/65 (32%), Positives = 27/65 (41%), Gaps = 1/65 (1%)
Query: 23 SFGLLDPKLCYLLDGILFIYGVILTALFLRVKFSRSADAPAYQQG-QNQLYNELNLGRRE 81
S G+ DP+ LD ++ L L R A +P YQ+G N L LG
Sbjct: 24 SLGIQDPERQESLDRPSYVASEESRILVLTELLERKAHSPFYQEGVSNALLKMAELGLTR 83
Query: 82 EYDVL 86
DVL
Sbjct: 84 AADVL 88
>gi|30089932 ankyrin repeat and SOCS box-containing 6 isoform 2
[Homo sapiens]
Length = 197
Score = 27.7 bits (60), Expect = 4.6
Identities = 21/65 (32%), Positives = 27/65 (41%), Gaps = 1/65 (1%)
Query: 23 SFGLLDPKLCYLLDGILFIYGVILTALFLRVKFSRSADAPAYQQG-QNQLYNELNLGRRE 81
S G+ DP+ LD ++ L L R A +P YQ+G N L LG
Sbjct: 24 SLGIQDPERQESLDRPSYVASEESRILVLTELLERKAHSPFYQEGVSNALLKMAELGLTR 83
Query: 82 EYDVL 86
DVL
Sbjct: 84 AADVL 88
>gi|239756473 PREDICTED: transmembrane protein 114 [Homo sapiens]
Length = 223
Score = 27.3 bits (59), Expect = 6.0
Identities = 15/36 (41%), Positives = 21/36 (58%)
Query: 26 LLDPKLCYLLDGILFIYGVILTALFLRVKFSRSADA 61
LL L LL GILF++G ++T + V + SA A
Sbjct: 129 LLQAYLLLLLTGILFLFGAMVTLAGISVYIAYSAAA 164
>gi|239752599 PREDICTED: transmembrane protein 114, partial [Homo
sapiens]
Length = 217
Score = 27.3 bits (59), Expect = 6.0
Identities = 15/36 (41%), Positives = 21/36 (58%)
Query: 26 LLDPKLCYLLDGILFIYGVILTALFLRVKFSRSADA 61
LL L LL GILF++G ++T + V + SA A
Sbjct: 123 LLQAYLLLLLTGILFLFGAMVTLAGISVYIAYSAAA 158
>gi|239745400 PREDICTED: transmembrane protein 114 [Homo sapiens]
Length = 122
Score = 27.3 bits (59), Expect = 6.0
Identities = 15/36 (41%), Positives = 21/36 (58%)
Query: 26 LLDPKLCYLLDGILFIYGVILTALFLRVKFSRSADA 61
LL L LL GILF++G ++T + V + SA A
Sbjct: 28 LLQAYLLLLLTGILFLFGAMVTLAGISVYIAYSAAA 63
>gi|40806170 spastin isoform 2 [Homo sapiens]
Length = 584
Score = 27.3 bits (59), Expect = 6.0
Identities = 19/61 (31%), Positives = 25/61 (40%), Gaps = 5/61 (8%)
Query: 85 VLDKRRGRDPEMGGKPRRKNPQEGLYNELQKDKMAEAYSEIGMKGERRRGKGHDGLYQGL 144
V+ K R + E G P+RK+P N L + K G+ G R Y GL
Sbjct: 186 VMAKDRLQLLESGAVPKRKDPLTHTSNSLPRSKTVMKTGSAGLSGHHRAPS-----YSGL 240
Query: 145 S 145
S
Sbjct: 241 S 241
>gi|11875211 spastin isoform 1 [Homo sapiens]
Length = 616
Score = 27.3 bits (59), Expect = 6.0
Identities = 22/83 (26%), Positives = 31/83 (37%), Gaps = 14/83 (16%)
Query: 64 YQQGQNQLYNE-LNLGRREEYDVLDKRRGRDPEMGGKPRRKNPQEGLYNELQKDKMAEAY 122
+ + Q +YN+ NL R + E G P+RK+P N L + K
Sbjct: 204 FSKSQTDVYNDSTNLACRNGH--------LQSESGAVPKRKDPLTHTSNSLPRSKTVMKT 255
Query: 123 SEIGMKGERRRGKGHDGLYQGLS 145
G+ G R Y GLS
Sbjct: 256 GSAGLSGHHRAPS-----YSGLS 273
>gi|34878777 ring finger protein 20 [Homo sapiens]
Length = 975
Score = 27.3 bits (59), Expect = 6.0
Identities = 21/84 (25%), Positives = 40/84 (47%), Gaps = 10/84 (11%)
Query: 56 SRSADAPAYQQGQNQLYNELNLGRREEYDVLDKRRGRDPEMGGKPRRKNPQEGLYNELQK 115
S+S+ + A Q+ N++ ++ + RE R R+ E + R+ +E E +K
Sbjct: 545 SQSSASKASQEDANEIKSKRDEEERE-------RERREKEREREREREKEKE---REREK 594
Query: 116 DKMAEAYSEIGMKGERRRGKGHDG 139
K+ E+ E ++ +GK DG
Sbjct: 595 QKLKESEKERDSAKDKEKGKHDDG 618
>gi|226437592 transmembrane protein 114 [Homo sapiens]
Length = 223
Score = 27.3 bits (59), Expect = 6.0
Identities = 15/36 (41%), Positives = 21/36 (58%)
Query: 26 LLDPKLCYLLDGILFIYGVILTALFLRVKFSRSADA 61
LL L LL GILF++G ++T + V + SA A
Sbjct: 129 LLQAYLLLLLTGILFLFGAMVTLAGISVYIAYSAAA 164
>gi|119120903 par-3 partitioning defective 3 homolog B isoform c
[Homo sapiens]
Length = 1136
Score = 27.3 bits (59), Expect = 6.0
Identities = 19/60 (31%), Positives = 26/60 (43%), Gaps = 1/60 (1%)
Query: 95 EMGGKPRRKNP-QEGLYNELQKDKMAEAYSEIGMKGERRRGKGHDGLYQGLSTATKDTYD 153
+ GGK +K + G E + +KM E IG K + R K GL + A YD
Sbjct: 815 DKGGKAEQKGTLKHGGLREEELEKMKEERERIGAKHQELREKQARGLLDYATGAIGSVYD 874
>gi|119120897 par-3 partitioning defective 3 homolog B isoform b
[Homo sapiens]
Length = 1143
Score = 27.3 bits (59), Expect = 6.0
Identities = 19/60 (31%), Positives = 26/60 (43%), Gaps = 1/60 (1%)
Query: 95 EMGGKPRRKNP-QEGLYNELQKDKMAEAYSEIGMKGERRRGKGHDGLYQGLSTATKDTYD 153
+ GGK +K + G E + +KM E IG K + R K GL + A YD
Sbjct: 822 DKGGKAEQKGTLKHGGLREEELEKMKEERERIGAKHQELREKQARGLLDYATGAIGSVYD 881
>gi|11386179 guanine nucleotide binding protein (G protein), gamma
transducing activity polypeptide 1 [Homo sapiens]
Length = 74
Score = 26.9 bits (58), Expect = 7.8
Identities = 16/44 (36%), Positives = 22/44 (50%), Gaps = 7/44 (15%)
Query: 69 NQLYNELNLGR-------REEYDVLDKRRGRDPEMGGKPRRKNP 105
+QL E+ L R E D +++R G DP + G P KNP
Sbjct: 20 DQLKKEVTLERMLVSKCCEEVRDYVEERSGEDPLVKGIPEDKNP 63
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.138 0.404
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 6,099,692
Number of Sequences: 37866
Number of extensions: 251712
Number of successful extensions: 703
Number of sequences better than 10.0: 26
Number of HSP's better than 10.0 without gapping: 8
Number of HSP's successfully gapped in prelim test: 18
Number of HSP's that attempted gapping in prelim test: 693
Number of HSP's gapped (non-prelim): 27
length of query: 163
length of database: 18,247,518
effective HSP length: 94
effective length of query: 69
effective length of database: 14,688,114
effective search space: 1013479866
effective search space used: 1013479866
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 58 (26.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.