Guide to the Human Genome
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Search of human proteins with 45545427

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|45545427 estrogen-related receptor gamma isoform 2 [Homo
sapiens]
         (435 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|45545429 estrogen-related receptor gamma isoform 2 [Homo sapi...   877   0.0  
gi|45545427 estrogen-related receptor gamma isoform 2 [Homo sapi...   877   0.0  
gi|45545433 estrogen-related receptor gamma isoform 1 [Homo sapi...   877   0.0  
gi|197209821 estrogen-related receptor gamma isoform 2 [Homo sap...   877   0.0  
gi|238550159 estrogen-related receptor beta [Homo sapiens]            697   0.0  
gi|18860920 estrogen-related receptor alpha [Homo sapiens]            476   e-134
gi|170295804 estrogen receptor alpha isoform 4 [Homo sapiens]         263   2e-70
gi|170295802 estrogen receptor alpha isoform 3 [Homo sapiens]         263   2e-70
gi|170295800 estrogen receptor alpha isoform 2 [Homo sapiens]         263   2e-70
gi|62821794 estrogen receptor alpha isoform 1 [Homo sapiens]          263   2e-70
gi|10835013 estrogen receptor beta isoform 1 [Homo sapiens]           242   6e-64
gi|4506755 retinoid X receptor, alpha [Homo sapiens]                  219   3e-57
gi|5902068 retinoid X receptor, gamma isoform a [Homo sapiens]        218   7e-57
gi|94538328 estrogen receptor beta isoform 2 [Homo sapiens]           217   2e-56
gi|94538325 estrogen receptor beta isoform 2 [Homo sapiens]           217   2e-56
gi|11415052 retinoid X receptor, beta [Homo sapiens]                  209   3e-54
gi|4506423 retinoic acid receptor, gamma isoform 1 [Homo sapiens]     199   3e-51
gi|112181200 retinoic acid receptor, gamma isoform 2 [Homo sapiens]   194   1e-49
gi|14149746 nuclear receptor subfamily 2, group F, member 2 isof...   191   9e-49
gi|5032173 nuclear receptor subfamily 2, group F, member 1 [Homo...   189   4e-48
gi|223718064 retinoic acid receptor, alpha isoform 1 [Homo sapiens]   188   9e-48
gi|4506419 retinoic acid receptor, alpha isoform 1 [Homo sapiens]     188   9e-48
gi|5453822 nuclear receptor subfamily 4, group A, member 2 [Homo...   187   2e-47
gi|67459914 retinoic acid receptor, alpha isoform 2 [Homo sapiens]    181   2e-45
gi|66528642 nuclear receptor subfamily 3, group C, member 1 isof...   180   2e-45
gi|66528611 nuclear receptor subfamily 3, group C, member 1 isof...   180   2e-45
gi|66528586 nuclear receptor subfamily 3, group C, member 1 isof...   180   2e-45
gi|66528563 nuclear receptor subfamily 3, group C, member 1 isof...   180   2e-45
gi|66528530 nuclear receptor subfamily 3, group C, member 1 isof...   180   2e-45
gi|4504133 nuclear receptor subfamily 3, group C, member 1 isofo...   180   2e-45

>gi|45545429 estrogen-related receptor gamma isoform 2 [Homo
           sapiens]
          Length = 435

 Score =  877 bits (2265), Expect = 0.0
 Identities = 435/435 (100%), Positives = 435/435 (100%)

Query: 1   MSNKDRHIDSSCSSFIKTEPSSPASLTDSVNHHSPGGSSDASGSYSSTMNGHQNGLDSPP 60
           MSNKDRHIDSSCSSFIKTEPSSPASLTDSVNHHSPGGSSDASGSYSSTMNGHQNGLDSPP
Sbjct: 1   MSNKDRHIDSSCSSFIKTEPSSPASLTDSVNHHSPGGSSDASGSYSSTMNGHQNGLDSPP 60

Query: 61  LYPSAPILGGSGPVRKLYDDCSSTIVEDPQTKCEYMLNSMPKRLCLVCGDIASGYHYGVA 120
           LYPSAPILGGSGPVRKLYDDCSSTIVEDPQTKCEYMLNSMPKRLCLVCGDIASGYHYGVA
Sbjct: 61  LYPSAPILGGSGPVRKLYDDCSSTIVEDPQTKCEYMLNSMPKRLCLVCGDIASGYHYGVA 120

Query: 121 SCEACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQACRFMKCLKVGMLKEGVRLDRV 180
           SCEACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQACRFMKCLKVGMLKEGVRLDRV
Sbjct: 121 SCEACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQACRFMKCLKVGMLKEGVRLDRV 180

Query: 181 RGGRQKYKRRIDAENSPYLNPQLVQPAKKPYNKIVSHLLVAEPEKIYAMPDPTVPDSDIK 240
           RGGRQKYKRRIDAENSPYLNPQLVQPAKKPYNKIVSHLLVAEPEKIYAMPDPTVPDSDIK
Sbjct: 181 RGGRQKYKRRIDAENSPYLNPQLVQPAKKPYNKIVSHLLVAEPEKIYAMPDPTVPDSDIK 240

Query: 241 ALTTLCDLADRELVVIIGWAKHIPGFSTLSLADQMSLLQSAWMEILILGVVYRSLSFEDE 300
           ALTTLCDLADRELVVIIGWAKHIPGFSTLSLADQMSLLQSAWMEILILGVVYRSLSFEDE
Sbjct: 241 ALTTLCDLADRELVVIIGWAKHIPGFSTLSLADQMSLLQSAWMEILILGVVYRSLSFEDE 300

Query: 301 LVYADDYIMDEDQSKLAGLLDLNNAILQLVKKYKSMKLEKEEFVTLKAIALANSDSMHIE 360
           LVYADDYIMDEDQSKLAGLLDLNNAILQLVKKYKSMKLEKEEFVTLKAIALANSDSMHIE
Sbjct: 301 LVYADDYIMDEDQSKLAGLLDLNNAILQLVKKYKSMKLEKEEFVTLKAIALANSDSMHIE 360

Query: 361 DVEAVQKLQDVLHEALQDYEAGQHMEDPRRAGKMLMTLPLLRQTSTKAVQHFYNIKLEGK 420
           DVEAVQKLQDVLHEALQDYEAGQHMEDPRRAGKMLMTLPLLRQTSTKAVQHFYNIKLEGK
Sbjct: 361 DVEAVQKLQDVLHEALQDYEAGQHMEDPRRAGKMLMTLPLLRQTSTKAVQHFYNIKLEGK 420

Query: 421 VPMHKLFLEMLEAKV 435
           VPMHKLFLEMLEAKV
Sbjct: 421 VPMHKLFLEMLEAKV 435


>gi|45545427 estrogen-related receptor gamma isoform 2 [Homo
           sapiens]
          Length = 435

 Score =  877 bits (2265), Expect = 0.0
 Identities = 435/435 (100%), Positives = 435/435 (100%)

Query: 1   MSNKDRHIDSSCSSFIKTEPSSPASLTDSVNHHSPGGSSDASGSYSSTMNGHQNGLDSPP 60
           MSNKDRHIDSSCSSFIKTEPSSPASLTDSVNHHSPGGSSDASGSYSSTMNGHQNGLDSPP
Sbjct: 1   MSNKDRHIDSSCSSFIKTEPSSPASLTDSVNHHSPGGSSDASGSYSSTMNGHQNGLDSPP 60

Query: 61  LYPSAPILGGSGPVRKLYDDCSSTIVEDPQTKCEYMLNSMPKRLCLVCGDIASGYHYGVA 120
           LYPSAPILGGSGPVRKLYDDCSSTIVEDPQTKCEYMLNSMPKRLCLVCGDIASGYHYGVA
Sbjct: 61  LYPSAPILGGSGPVRKLYDDCSSTIVEDPQTKCEYMLNSMPKRLCLVCGDIASGYHYGVA 120

Query: 121 SCEACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQACRFMKCLKVGMLKEGVRLDRV 180
           SCEACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQACRFMKCLKVGMLKEGVRLDRV
Sbjct: 121 SCEACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQACRFMKCLKVGMLKEGVRLDRV 180

Query: 181 RGGRQKYKRRIDAENSPYLNPQLVQPAKKPYNKIVSHLLVAEPEKIYAMPDPTVPDSDIK 240
           RGGRQKYKRRIDAENSPYLNPQLVQPAKKPYNKIVSHLLVAEPEKIYAMPDPTVPDSDIK
Sbjct: 181 RGGRQKYKRRIDAENSPYLNPQLVQPAKKPYNKIVSHLLVAEPEKIYAMPDPTVPDSDIK 240

Query: 241 ALTTLCDLADRELVVIIGWAKHIPGFSTLSLADQMSLLQSAWMEILILGVVYRSLSFEDE 300
           ALTTLCDLADRELVVIIGWAKHIPGFSTLSLADQMSLLQSAWMEILILGVVYRSLSFEDE
Sbjct: 241 ALTTLCDLADRELVVIIGWAKHIPGFSTLSLADQMSLLQSAWMEILILGVVYRSLSFEDE 300

Query: 301 LVYADDYIMDEDQSKLAGLLDLNNAILQLVKKYKSMKLEKEEFVTLKAIALANSDSMHIE 360
           LVYADDYIMDEDQSKLAGLLDLNNAILQLVKKYKSMKLEKEEFVTLKAIALANSDSMHIE
Sbjct: 301 LVYADDYIMDEDQSKLAGLLDLNNAILQLVKKYKSMKLEKEEFVTLKAIALANSDSMHIE 360

Query: 361 DVEAVQKLQDVLHEALQDYEAGQHMEDPRRAGKMLMTLPLLRQTSTKAVQHFYNIKLEGK 420
           DVEAVQKLQDVLHEALQDYEAGQHMEDPRRAGKMLMTLPLLRQTSTKAVQHFYNIKLEGK
Sbjct: 361 DVEAVQKLQDVLHEALQDYEAGQHMEDPRRAGKMLMTLPLLRQTSTKAVQHFYNIKLEGK 420

Query: 421 VPMHKLFLEMLEAKV 435
           VPMHKLFLEMLEAKV
Sbjct: 421 VPMHKLFLEMLEAKV 435


>gi|45545433 estrogen-related receptor gamma isoform 1 [Homo
           sapiens]
          Length = 458

 Score =  877 bits (2265), Expect = 0.0
 Identities = 435/435 (100%), Positives = 435/435 (100%)

Query: 1   MSNKDRHIDSSCSSFIKTEPSSPASLTDSVNHHSPGGSSDASGSYSSTMNGHQNGLDSPP 60
           MSNKDRHIDSSCSSFIKTEPSSPASLTDSVNHHSPGGSSDASGSYSSTMNGHQNGLDSPP
Sbjct: 24  MSNKDRHIDSSCSSFIKTEPSSPASLTDSVNHHSPGGSSDASGSYSSTMNGHQNGLDSPP 83

Query: 61  LYPSAPILGGSGPVRKLYDDCSSTIVEDPQTKCEYMLNSMPKRLCLVCGDIASGYHYGVA 120
           LYPSAPILGGSGPVRKLYDDCSSTIVEDPQTKCEYMLNSMPKRLCLVCGDIASGYHYGVA
Sbjct: 84  LYPSAPILGGSGPVRKLYDDCSSTIVEDPQTKCEYMLNSMPKRLCLVCGDIASGYHYGVA 143

Query: 121 SCEACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQACRFMKCLKVGMLKEGVRLDRV 180
           SCEACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQACRFMKCLKVGMLKEGVRLDRV
Sbjct: 144 SCEACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQACRFMKCLKVGMLKEGVRLDRV 203

Query: 181 RGGRQKYKRRIDAENSPYLNPQLVQPAKKPYNKIVSHLLVAEPEKIYAMPDPTVPDSDIK 240
           RGGRQKYKRRIDAENSPYLNPQLVQPAKKPYNKIVSHLLVAEPEKIYAMPDPTVPDSDIK
Sbjct: 204 RGGRQKYKRRIDAENSPYLNPQLVQPAKKPYNKIVSHLLVAEPEKIYAMPDPTVPDSDIK 263

Query: 241 ALTTLCDLADRELVVIIGWAKHIPGFSTLSLADQMSLLQSAWMEILILGVVYRSLSFEDE 300
           ALTTLCDLADRELVVIIGWAKHIPGFSTLSLADQMSLLQSAWMEILILGVVYRSLSFEDE
Sbjct: 264 ALTTLCDLADRELVVIIGWAKHIPGFSTLSLADQMSLLQSAWMEILILGVVYRSLSFEDE 323

Query: 301 LVYADDYIMDEDQSKLAGLLDLNNAILQLVKKYKSMKLEKEEFVTLKAIALANSDSMHIE 360
           LVYADDYIMDEDQSKLAGLLDLNNAILQLVKKYKSMKLEKEEFVTLKAIALANSDSMHIE
Sbjct: 324 LVYADDYIMDEDQSKLAGLLDLNNAILQLVKKYKSMKLEKEEFVTLKAIALANSDSMHIE 383

Query: 361 DVEAVQKLQDVLHEALQDYEAGQHMEDPRRAGKMLMTLPLLRQTSTKAVQHFYNIKLEGK 420
           DVEAVQKLQDVLHEALQDYEAGQHMEDPRRAGKMLMTLPLLRQTSTKAVQHFYNIKLEGK
Sbjct: 384 DVEAVQKLQDVLHEALQDYEAGQHMEDPRRAGKMLMTLPLLRQTSTKAVQHFYNIKLEGK 443

Query: 421 VPMHKLFLEMLEAKV 435
           VPMHKLFLEMLEAKV
Sbjct: 444 VPMHKLFLEMLEAKV 458


>gi|197209821 estrogen-related receptor gamma isoform 2 [Homo
           sapiens]
          Length = 435

 Score =  877 bits (2265), Expect = 0.0
 Identities = 435/435 (100%), Positives = 435/435 (100%)

Query: 1   MSNKDRHIDSSCSSFIKTEPSSPASLTDSVNHHSPGGSSDASGSYSSTMNGHQNGLDSPP 60
           MSNKDRHIDSSCSSFIKTEPSSPASLTDSVNHHSPGGSSDASGSYSSTMNGHQNGLDSPP
Sbjct: 1   MSNKDRHIDSSCSSFIKTEPSSPASLTDSVNHHSPGGSSDASGSYSSTMNGHQNGLDSPP 60

Query: 61  LYPSAPILGGSGPVRKLYDDCSSTIVEDPQTKCEYMLNSMPKRLCLVCGDIASGYHYGVA 120
           LYPSAPILGGSGPVRKLYDDCSSTIVEDPQTKCEYMLNSMPKRLCLVCGDIASGYHYGVA
Sbjct: 61  LYPSAPILGGSGPVRKLYDDCSSTIVEDPQTKCEYMLNSMPKRLCLVCGDIASGYHYGVA 120

Query: 121 SCEACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQACRFMKCLKVGMLKEGVRLDRV 180
           SCEACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQACRFMKCLKVGMLKEGVRLDRV
Sbjct: 121 SCEACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQACRFMKCLKVGMLKEGVRLDRV 180

Query: 181 RGGRQKYKRRIDAENSPYLNPQLVQPAKKPYNKIVSHLLVAEPEKIYAMPDPTVPDSDIK 240
           RGGRQKYKRRIDAENSPYLNPQLVQPAKKPYNKIVSHLLVAEPEKIYAMPDPTVPDSDIK
Sbjct: 181 RGGRQKYKRRIDAENSPYLNPQLVQPAKKPYNKIVSHLLVAEPEKIYAMPDPTVPDSDIK 240

Query: 241 ALTTLCDLADRELVVIIGWAKHIPGFSTLSLADQMSLLQSAWMEILILGVVYRSLSFEDE 300
           ALTTLCDLADRELVVIIGWAKHIPGFSTLSLADQMSLLQSAWMEILILGVVYRSLSFEDE
Sbjct: 241 ALTTLCDLADRELVVIIGWAKHIPGFSTLSLADQMSLLQSAWMEILILGVVYRSLSFEDE 300

Query: 301 LVYADDYIMDEDQSKLAGLLDLNNAILQLVKKYKSMKLEKEEFVTLKAIALANSDSMHIE 360
           LVYADDYIMDEDQSKLAGLLDLNNAILQLVKKYKSMKLEKEEFVTLKAIALANSDSMHIE
Sbjct: 301 LVYADDYIMDEDQSKLAGLLDLNNAILQLVKKYKSMKLEKEEFVTLKAIALANSDSMHIE 360

Query: 361 DVEAVQKLQDVLHEALQDYEAGQHMEDPRRAGKMLMTLPLLRQTSTKAVQHFYNIKLEGK 420
           DVEAVQKLQDVLHEALQDYEAGQHMEDPRRAGKMLMTLPLLRQTSTKAVQHFYNIKLEGK
Sbjct: 361 DVEAVQKLQDVLHEALQDYEAGQHMEDPRRAGKMLMTLPLLRQTSTKAVQHFYNIKLEGK 420

Query: 421 VPMHKLFLEMLEAKV 435
           VPMHKLFLEMLEAKV
Sbjct: 421 VPMHKLFLEMLEAKV 435


>gi|238550159 estrogen-related receptor beta [Homo sapiens]
          Length = 508

 Score =  697 bits (1800), Expect = 0.0
 Identities = 338/435 (77%), Positives = 388/435 (89%), Gaps = 2/435 (0%)

Query: 1   MSNKDRHIDSSCSSFIKTEPSSPASLTDSVNHHSPGGSSDASGSYSSTMNGHQNGLDSPP 60
           MS+ DRH+ SSC SFIKTEPSSP+S  D+++HHSP GSSDASG +   +  H NGLDSPP
Sbjct: 1   MSSDDRHLGSSCGSFIKTEPSSPSSGIDALSHHSPSGSSDASGGFGLALGTHANGLDSPP 60

Query: 61  LYPSAPILGGSGPVRKLYDDCSSTIVEDPQTKCEYMLNSMPKRLCLVCGDIASGYHYGVA 120
           ++  A +  G  P RK Y+DC+S I+ED   KCEYMLN++PKRLCLVCGDIASGYHYGVA
Sbjct: 61  MFAGAGL--GGTPCRKSYEDCASGIMEDSAIKCEYMLNAIPKRLCLVCGDIASGYHYGVA 118

Query: 121 SCEACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQACRFMKCLKVGMLKEGVRLDRV 180
           SCEACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQACRFMKCLKVGMLKEGVRLDRV
Sbjct: 119 SCEACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQACRFMKCLKVGMLKEGVRLDRV 178

Query: 181 RGGRQKYKRRIDAENSPYLNPQLVQPAKKPYNKIVSHLLVAEPEKIYAMPDPTVPDSDIK 240
           RGGRQKYKRR+D+E+SPYL+ Q+  PAKKP  KIVS+LLVAEP+K+YAMP P +P+ DIK
Sbjct: 179 RGGRQKYKRRLDSESSPYLSLQISPPAKKPLTKIVSYLLVAEPDKLYAMPPPGMPEGDIK 238

Query: 241 ALTTLCDLADRELVVIIGWAKHIPGFSTLSLADQMSLLQSAWMEILILGVVYRSLSFEDE 300
           ALTTLCDLADRELVVIIGWAKHIPGFS+LSL DQMSLLQSAWMEILILG+VYRSL ++D+
Sbjct: 239 ALTTLCDLADRELVVIIGWAKHIPGFSSLSLGDQMSLLQSAWMEILILGIVYRSLPYDDK 298

Query: 301 LVYADDYIMDEDQSKLAGLLDLNNAILQLVKKYKSMKLEKEEFVTLKAIALANSDSMHIE 360
           LVYA+DYIMDE+ S+LAGLL+L  AILQLV++YK +K+EKEEFVTLKA+ALANSDSM+IE
Sbjct: 299 LVYAEDYIMDEEHSRLAGLLELYRAILQLVRRYKKLKVEKEEFVTLKALALANSDSMYIE 358

Query: 361 DVEAVQKLQDVLHEALQDYEAGQHMEDPRRAGKMLMTLPLLRQTSTKAVQHFYNIKLEGK 420
           D+EAVQKLQD+LHEALQDYE  Q  E+P R GK+L+TLPLLRQT+ KAVQHFY++KL+GK
Sbjct: 359 DLEAVQKLQDLLHEALQDYELSQRHEEPWRTGKLLLTLPLLRQTAAKAVQHFYSVKLQGK 418

Query: 421 VPMHKLFLEMLEAKV 435
           VPMHKLFLEMLEAKV
Sbjct: 419 VPMHKLFLEMLEAKV 433


>gi|18860920 estrogen-related receptor alpha [Homo sapiens]
          Length = 423

 Score =  476 bits (1226), Expect = e-134
 Identities = 249/436 (57%), Positives = 310/436 (71%), Gaps = 44/436 (10%)

Query: 15  FIKTEPSSPASLTDSVNHHSPGGSSDASGSYSSTMNGHQNGLDSPPLYPSAPILGGSGPV 74
           +IK EP+SP          SP GSS+                      P   +  G  P 
Sbjct: 12  YIKAEPASP---------DSPKGSSETETE------------------PPVALAPGPAPT 44

Query: 75  RKL----YDDCSSTIVEDPQTKCEYMLNSMPKRLCLVCGDIASGYHYGVASCEACKAFFK 130
           R L     ++         Q   + +L+S+PKRLCLVCGD+ASGYHYGVASCEACKAFFK
Sbjct: 45  RCLPGHKEEEDGEGAGPGEQGGGKLVLSSLPKRLCLVCGDVASGYHYGVASCEACKAFFK 104

Query: 131 RTIQGNIEYSCPATNECEITKRRRKSCQACRFMKCLKVGMLKEGVRLDRVRGGRQKYKRR 190
           RTIQG+IEYSCPA+NECEITKRRRK+CQACRF KCL+VGMLKEGVRLDRVRGGRQKYKRR
Sbjct: 105 RTIQGSIEYSCPASNECEITKRRRKACQACRFTKCLRVGMLKEGVRLDRVRGGRQKYKRR 164

Query: 191 IDAENSPYLNPQLVQP---------AKKPYNKIVSHLLVAEPEKIYAMPDPTVPDSDIKA 241
            + +  P+  P    P            P N +VSHLLV EPEK+YAMPDP  PD  + A
Sbjct: 165 PEVDPLPFPGPFPAGPLAVAGGPRKTAAPVNALVSHLLVVEPEKLYAMPDPAGPDGHLPA 224

Query: 242 LTTLCDLADRELVVIIGWAKHIPGFSTLSLADQMSLLQSAWMEILILGVVYRSLSFEDEL 301
           + TLCDL DRE+VV I WAK IPGFS+LSL+DQMS+LQS WME+L+LGV  RSL  +DEL
Sbjct: 225 VATLCDLFDREIVVTISWAKSIPGFSSLSLSDQMSVLQSVWMEVLVLGVAQRSLPLQDEL 284

Query: 302 VYADDYIMDEDQSKLAGLLDLNNAILQLVKKYKSMKLEKEEFVTLKAIALANSDSMHIED 361
            +A+D ++DE+ ++ AGL +L  A+LQLV++ ++++LE+EE+V LKA+ALANSDS+HIED
Sbjct: 285 AFAEDLVLDEEGARAAGLGELGAALLQLVRRLQALRLEREEYVLLKALALANSDSVHIED 344

Query: 362 VEAVQKLQDVLHEALQDYEAGQ----HMEDPRRAGKMLMTLPLLRQTSTKAVQHFYNIKL 417
            EAV++L++ LHEAL +YEAG+       + RRAG++L+TLPLLRQT+ K + HFY +KL
Sbjct: 345 AEAVEQLREALHEALLEYEAGRAGPGGGAERRRAGRLLLTLPLLRQTAGKVLAHFYGVKL 404

Query: 418 EGKVPMHKLFLEMLEA 433
           EGKVPMHKLFLEMLEA
Sbjct: 405 EGKVPMHKLFLEMLEA 420


>gi|170295804 estrogen receptor alpha isoform 4 [Homo sapiens]
          Length = 595

 Score =  263 bits (673), Expect = 2e-70
 Identities = 151/372 (40%), Positives = 229/372 (61%), Gaps = 35/372 (9%)

Query: 96  MLNSMPKRLCLVCGDIASGYHYGVASCEACKAFFKRTIQGNIEYSCPATNECEITKRRRK 155
           M ++   R C VC D ASGYHYGV SCE CKAFFKR+IQG+ +Y CPATN+C I K RRK
Sbjct: 176 MESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRK 235

Query: 156 SCQACRFMKCLKVGMLKEGVRLDRVRGGRQ-KYKR-RIDAEN-------------SPYLN 200
           SCQACR  KC +VGM+K G+R DR RGGR  K+KR R D E              + + +
Sbjct: 236 SCQACRLRKCYEVGMMKGGIRKDR-RGGRMLKHKRQRDDGEGRGEVGSAGDMRAANLWPS 294

Query: 201 PQLVQPAKK-------PYNKIVSHLLVAEPEKIYAMPDPTVPDSDIKALTTLCDLADREL 253
           P +++ +KK         +++VS LL AEP  +Y+  DPT P S+   +  L +LADREL
Sbjct: 295 PLMIKRSKKNSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADREL 354

Query: 254 VVIIGWAKHIPGFSTLSLADQMSLLQSAWMEILILGVVYRSLSFEDELVYADDYIMDEDQ 313
           V +I WAK +PGF  L+L DQ+ LL+ AW+EIL++G+V+RS+    +L++A + ++D +Q
Sbjct: 355 VHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQ 414

Query: 314 SK-LAGLLDLNNAILQLVKKYKSMKLEKEEFVTLKAIALAN--------SDSMHIEDVEA 364
            K + G++++ + +L    +++ M L+ EEFV LK+I L N        S    +E+ + 
Sbjct: 415 GKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDH 474

Query: 365 VQKLQDVLHEALQDYEAGQHM---EDPRRAGKMLMTLPLLRQTSTKAVQHFYNIKLEGKV 421
           + ++ D + + L    A   +   +  +R  ++L+ L  +R  S K ++H Y++K +  V
Sbjct: 475 IHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVV 534

Query: 422 PMHKLFLEMLEA 433
           P++ L LEML+A
Sbjct: 535 PLYDLLLEMLDA 546


>gi|170295802 estrogen receptor alpha isoform 3 [Homo sapiens]
          Length = 595

 Score =  263 bits (673), Expect = 2e-70
 Identities = 151/372 (40%), Positives = 229/372 (61%), Gaps = 35/372 (9%)

Query: 96  MLNSMPKRLCLVCGDIASGYHYGVASCEACKAFFKRTIQGNIEYSCPATNECEITKRRRK 155
           M ++   R C VC D ASGYHYGV SCE CKAFFKR+IQG+ +Y CPATN+C I K RRK
Sbjct: 176 MESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRK 235

Query: 156 SCQACRFMKCLKVGMLKEGVRLDRVRGGRQ-KYKR-RIDAEN-------------SPYLN 200
           SCQACR  KC +VGM+K G+R DR RGGR  K+KR R D E              + + +
Sbjct: 236 SCQACRLRKCYEVGMMKGGIRKDR-RGGRMLKHKRQRDDGEGRGEVGSAGDMRAANLWPS 294

Query: 201 PQLVQPAKK-------PYNKIVSHLLVAEPEKIYAMPDPTVPDSDIKALTTLCDLADREL 253
           P +++ +KK         +++VS LL AEP  +Y+  DPT P S+   +  L +LADREL
Sbjct: 295 PLMIKRSKKNSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADREL 354

Query: 254 VVIIGWAKHIPGFSTLSLADQMSLLQSAWMEILILGVVYRSLSFEDELVYADDYIMDEDQ 313
           V +I WAK +PGF  L+L DQ+ LL+ AW+EIL++G+V+RS+    +L++A + ++D +Q
Sbjct: 355 VHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQ 414

Query: 314 SK-LAGLLDLNNAILQLVKKYKSMKLEKEEFVTLKAIALAN--------SDSMHIEDVEA 364
            K + G++++ + +L    +++ M L+ EEFV LK+I L N        S    +E+ + 
Sbjct: 415 GKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDH 474

Query: 365 VQKLQDVLHEALQDYEAGQHM---EDPRRAGKMLMTLPLLRQTSTKAVQHFYNIKLEGKV 421
           + ++ D + + L    A   +   +  +R  ++L+ L  +R  S K ++H Y++K +  V
Sbjct: 475 IHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVV 534

Query: 422 PMHKLFLEMLEA 433
           P++ L LEML+A
Sbjct: 535 PLYDLLLEMLDA 546


>gi|170295800 estrogen receptor alpha isoform 2 [Homo sapiens]
          Length = 595

 Score =  263 bits (673), Expect = 2e-70
 Identities = 151/372 (40%), Positives = 229/372 (61%), Gaps = 35/372 (9%)

Query: 96  MLNSMPKRLCLVCGDIASGYHYGVASCEACKAFFKRTIQGNIEYSCPATNECEITKRRRK 155
           M ++   R C VC D ASGYHYGV SCE CKAFFKR+IQG+ +Y CPATN+C I K RRK
Sbjct: 176 MESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRK 235

Query: 156 SCQACRFMKCLKVGMLKEGVRLDRVRGGRQ-KYKR-RIDAEN-------------SPYLN 200
           SCQACR  KC +VGM+K G+R DR RGGR  K+KR R D E              + + +
Sbjct: 236 SCQACRLRKCYEVGMMKGGIRKDR-RGGRMLKHKRQRDDGEGRGEVGSAGDMRAANLWPS 294

Query: 201 PQLVQPAKK-------PYNKIVSHLLVAEPEKIYAMPDPTVPDSDIKALTTLCDLADREL 253
           P +++ +KK         +++VS LL AEP  +Y+  DPT P S+   +  L +LADREL
Sbjct: 295 PLMIKRSKKNSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADREL 354

Query: 254 VVIIGWAKHIPGFSTLSLADQMSLLQSAWMEILILGVVYRSLSFEDELVYADDYIMDEDQ 313
           V +I WAK +PGF  L+L DQ+ LL+ AW+EIL++G+V+RS+    +L++A + ++D +Q
Sbjct: 355 VHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQ 414

Query: 314 SK-LAGLLDLNNAILQLVKKYKSMKLEKEEFVTLKAIALAN--------SDSMHIEDVEA 364
            K + G++++ + +L    +++ M L+ EEFV LK+I L N        S    +E+ + 
Sbjct: 415 GKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDH 474

Query: 365 VQKLQDVLHEALQDYEAGQHM---EDPRRAGKMLMTLPLLRQTSTKAVQHFYNIKLEGKV 421
           + ++ D + + L    A   +   +  +R  ++L+ L  +R  S K ++H Y++K +  V
Sbjct: 475 IHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVV 534

Query: 422 PMHKLFLEMLEA 433
           P++ L LEML+A
Sbjct: 535 PLYDLLLEMLDA 546


>gi|62821794 estrogen receptor alpha isoform 1 [Homo sapiens]
          Length = 595

 Score =  263 bits (673), Expect = 2e-70
 Identities = 151/372 (40%), Positives = 229/372 (61%), Gaps = 35/372 (9%)

Query: 96  MLNSMPKRLCLVCGDIASGYHYGVASCEACKAFFKRTIQGNIEYSCPATNECEITKRRRK 155
           M ++   R C VC D ASGYHYGV SCE CKAFFKR+IQG+ +Y CPATN+C I K RRK
Sbjct: 176 MESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRK 235

Query: 156 SCQACRFMKCLKVGMLKEGVRLDRVRGGRQ-KYKR-RIDAEN-------------SPYLN 200
           SCQACR  KC +VGM+K G+R DR RGGR  K+KR R D E              + + +
Sbjct: 236 SCQACRLRKCYEVGMMKGGIRKDR-RGGRMLKHKRQRDDGEGRGEVGSAGDMRAANLWPS 294

Query: 201 PQLVQPAKK-------PYNKIVSHLLVAEPEKIYAMPDPTVPDSDIKALTTLCDLADREL 253
           P +++ +KK         +++VS LL AEP  +Y+  DPT P S+   +  L +LADREL
Sbjct: 295 PLMIKRSKKNSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADREL 354

Query: 254 VVIIGWAKHIPGFSTLSLADQMSLLQSAWMEILILGVVYRSLSFEDELVYADDYIMDEDQ 313
           V +I WAK +PGF  L+L DQ+ LL+ AW+EIL++G+V+RS+    +L++A + ++D +Q
Sbjct: 355 VHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQ 414

Query: 314 SK-LAGLLDLNNAILQLVKKYKSMKLEKEEFVTLKAIALAN--------SDSMHIEDVEA 364
            K + G++++ + +L    +++ M L+ EEFV LK+I L N        S    +E+ + 
Sbjct: 415 GKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDH 474

Query: 365 VQKLQDVLHEALQDYEAGQHM---EDPRRAGKMLMTLPLLRQTSTKAVQHFYNIKLEGKV 421
           + ++ D + + L    A   +   +  +R  ++L+ L  +R  S K ++H Y++K +  V
Sbjct: 475 IHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVV 534

Query: 422 PMHKLFLEMLEA 433
           P++ L LEML+A
Sbjct: 535 PLYDLLLEMLDA 546


>gi|10835013 estrogen receptor beta isoform 1 [Homo sapiens]
          Length = 530

 Score =  242 bits (617), Expect = 6e-64
 Identities = 139/355 (39%), Positives = 215/355 (60%), Gaps = 28/355 (7%)

Query: 105 CLVCGDIASGYHYGVASCEACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQACRFMK 164
           C VC D ASGYHYGV SCE CKAFFKR+IQG+ +Y CPATN+C I K RRKSCQACR  K
Sbjct: 149 CAVCSDYASGYHYGVWSCEGCKAFFKRSIQGHNDYICPATNQCTIDKNRRKSCQACRLRK 208

Query: 165 CLKVGMLKEGVRLDRVRGGRQKYKRRIDAE------------NSPYLNPQLVQPAKKPYN 212
           C +VGM+K G R +R      + +R  D +            ++P +  +L+  A  P  
Sbjct: 209 CYEVGMVKCGSRRERCGYRLVRRQRSADEQLHCAGKAKRSGGHAPRVR-ELLLDALSP-E 266

Query: 213 KIVSHLLVAEPEKIYAMPDPTVPDSDIKALTTLCDLADRELVVIIGWAKHIPGFSTLSLA 272
           ++V  LL AEP  +  +  P+ P ++   + +L  LAD+ELV +I WAK IPGF  LSL 
Sbjct: 267 QLVLTLLEAEPPHV-LISRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLF 325

Query: 273 DQMSLLQSAWMEILILGVVYRSLSFEDELVYADDYIMDEDQSK-LAGLLDLNNAILQLVK 331
           DQ+ LL+S WME+L++G+++RS+    +L++A D ++D D+ K + G+L++ + +L    
Sbjct: 326 DQVRLLESCWMEVLMMGLMWRSIDHPGKLIFAPDLVLDRDEGKCVEGILEIFDMLLATTS 385

Query: 332 KYKSMKLEKEEFVTLKAIALANSDSMHI----EDVEAVQKLQDVLHEALQD------YEA 381
           +++ +KL+ +E++ +KA+ L NS    +    +D ++ +KL  +L+ A+ D       ++
Sbjct: 386 RFRELKLQHKEYLCVKAMILLNSSMYPLVTATQDADSSRKLAHLLN-AVTDALVWVIAKS 444

Query: 382 G-QHMEDPRRAGKMLMTLPLLRQTSTKAVQHFYNIKLEGKVPMHKLFLEMLEAKV 435
           G    +   R   +LM L  +R  S K ++H  N+K +  VP++ L LEML A V
Sbjct: 445 GISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVVPVYDLLLEMLNAHV 499


>gi|4506755 retinoid X receptor, alpha [Homo sapiens]
          Length = 462

 Score =  219 bits (559), Expect = 3e-57
 Identities = 145/447 (32%), Positives = 229/447 (51%), Gaps = 40/447 (8%)

Query: 18  TEPSSPASLTDSVNHHSPG---GSSDASGSYSSTMNGHQNGLDSP------PL------Y 62
           T P+   S+     H S G   GS     S  ST++   NG+  P      P+       
Sbjct: 20  TSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSV 79

Query: 63  PSAPILG---GSGPVRKLYDDCSSTIVEDPQTKCEYMLN----------SMPKRLCLVCG 109
           P+ P LG   GS  +    +  SS+    P      +L           S  K +C +CG
Sbjct: 80  PTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICG 139

Query: 110 DIASGYHYGVASCEACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQACRFMKCLKVG 169
           D +SG HYGV SCE CK FFKRT++ ++ Y+C    +C I KR+R  CQ CR+ KCL +G
Sbjct: 140 DRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMG 199

Query: 170 MLKEGVRLDRVRGGRQKYKRRIDAENSPYLNPQLVQPAKKPYNKIVSHLLVAEPE-KIYA 228
           M +E V+ +R RG   K +   + E++   N  +      P  +I+   L  EP+ + Y 
Sbjct: 200 MKREAVQEERQRG---KDRNENEVESTSSANEDM------PVERILEAELAVEPKTETYV 250

Query: 229 MPDPTV-PDSDIKALTTLCDLADRELVVIIGWAKHIPGFSTLSLADQMSLLQSAWMEILI 287
             +  + P S    +T +C  AD++L  ++ WAK IP FS L L DQ+ LL++ W E+LI
Sbjct: 251 EANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLI 310

Query: 288 LGVVYRSLSFEDELVYADDYIMDEDQSKLAGLLDLNNAIL-QLVKKYKSMKLEKEEFVTL 346
               +RS++ +D ++ A    +  + +  AG+  + + +L +LV K + M+++K E   L
Sbjct: 311 ASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCL 370

Query: 347 KAIALANSDSMHIEDVEAVQKLQDVLHEALQDYEAGQHMEDPRRAGKMLMTLPLLRQTST 406
           +AI L N DS  + +   V+ L++ ++ +L+ Y   ++ E P R  K+L+ LP LR    
Sbjct: 371 RAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGL 430

Query: 407 KAVQHFYNIKLEGKVPMHKLFLEMLEA 433
           K ++H +  KL G  P+    +EMLEA
Sbjct: 431 KCLEHLFFFKLIGDTPIDTFLMEMLEA 457


>gi|5902068 retinoid X receptor, gamma isoform a [Homo sapiens]
          Length = 463

 Score =  218 bits (556), Expect = 7e-57
 Identities = 119/335 (35%), Positives = 189/335 (56%), Gaps = 11/335 (3%)

Query: 99  SMPKRLCLVCGDIASGYHYGVASCEACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQ 158
           S+ K +C +CGD +SG HYGV SCE CK FFKRTI+ ++ Y+C    +C I KR+R  CQ
Sbjct: 133 SLVKHICAICGDRSSGKHYGVYSCEGCKGFFKRTIRKDLIYTCRDNKDCLIDKRQRNRCQ 192

Query: 159 ACRFMKCLKVGMLKEGVRLDRVRGGRQKYKRRIDAENSPYLNPQLVQPAKKPYNKIVSHL 218
            CR+ KCL +GM +E V+ +R R  R++ +   +   S +           P  +I+   
Sbjct: 193 YCRYQKCLVMGMKREAVQEERQR-SRERAESEAECATSGH--------EDMPVERILEAE 243

Query: 219 LVAEPEKIYAMPDPTVPDSDIKALTTLCDLADRELVVIIGWAKHIPGFSTLSLADQMSLL 278
           L  EP K  +  D  + +S    +T +C  AD++L  ++ WAK IP FS L+L DQ+ LL
Sbjct: 244 LAVEP-KTESYGDMNMENSTNDPVTNICHAADKQLFTLVEWAKRIPHFSDLTLEDQVILL 302

Query: 279 QSAWMEILILGVVYRSLSFEDELVYADDYIMDEDQSKLAGLLDLNNAIL-QLVKKYKSMK 337
           ++ W E+LI    +RS+S +D ++ A    +    +  AG+  + + +L +LV K K M+
Sbjct: 303 RAGWNELLIASFSHRSVSVQDGILLATGLHVHRSSAHSAGVGSIFDRVLTELVSKMKDMQ 362

Query: 338 LEKEEFVTLKAIALANSDSMHIEDVEAVQKLQDVLHEALQDYEAGQHMEDPRRAGKMLMT 397
           ++K E   L+AI L N D+  + +   V+ L++ ++  L+ Y   ++ E P R  K+L+ 
Sbjct: 363 MDKSELGCLRAIVLFNPDAKGLSNPSEVETLREKVYATLEAYTKQKYPEQPGRFAKLLLR 422

Query: 398 LPLLRQTSTKAVQHFYNIKLEGKVPMHKLFLEMLE 432
           LP LR    K ++H +  KL G  P+    +EMLE
Sbjct: 423 LPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLE 457


>gi|94538328 estrogen receptor beta isoform 2 [Homo sapiens]
          Length = 495

 Score =  217 bits (552), Expect = 2e-56
 Identities = 117/286 (40%), Positives = 181/286 (63%), Gaps = 20/286 (6%)

Query: 105 CLVCGDIASGYHYGVASCEACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQACRFMK 164
           C VC D ASGYHYGV SCE CKAFFKR+IQG+ +Y CPATN+C I K RRKSCQACR  K
Sbjct: 149 CAVCSDYASGYHYGVWSCEGCKAFFKRSIQGHNDYICPATNQCTIDKNRRKSCQACRLRK 208

Query: 165 CLKVGMLKEGVRLDRVRGGRQKYKRRIDAE------------NSPYLNPQLVQPAKKPYN 212
           C +VGM+K G R +R      + +R  D +            ++P +  +L+  A  P  
Sbjct: 209 CYEVGMVKCGSRRERCGYRLVRRQRSADEQLHCAGKAKRSGGHAPRVR-ELLLDALSP-E 266

Query: 213 KIVSHLLVAEPEKIYAMPDPTVPDSDIKALTTLCDLADRELVVIIGWAKHIPGFSTLSLA 272
           ++V  LL AEP  +  +  P+ P ++   + +L  LAD+ELV +I WAK IPGF  LSL 
Sbjct: 267 QLVLTLLEAEPPHV-LISRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLF 325

Query: 273 DQMSLLQSAWMEILILGVVYRSLSFEDELVYADDYIMDEDQSK-LAGLLDLNNAILQLVK 331
           DQ+ LL+S WME+L++G+++RS+    +L++A D ++D D+ K + G+L++ + +L    
Sbjct: 326 DQVRLLESCWMEVLMMGLMWRSIDHPGKLIFAPDLVLDRDEGKCVEGILEIFDMLLATTS 385

Query: 332 KYKSMKLEKEEFVTLKAIALANSDSMHI----EDVEAVQKLQDVLH 373
           +++ +KL+ +E++ +KA+ L NS    +    +D ++ +KL  +L+
Sbjct: 386 RFRELKLQHKEYLCVKAMILLNSSMYPLVTATQDADSSRKLAHLLN 431


>gi|94538325 estrogen receptor beta isoform 2 [Homo sapiens]
          Length = 495

 Score =  217 bits (552), Expect = 2e-56
 Identities = 117/286 (40%), Positives = 181/286 (63%), Gaps = 20/286 (6%)

Query: 105 CLVCGDIASGYHYGVASCEACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQACRFMK 164
           C VC D ASGYHYGV SCE CKAFFKR+IQG+ +Y CPATN+C I K RRKSCQACR  K
Sbjct: 149 CAVCSDYASGYHYGVWSCEGCKAFFKRSIQGHNDYICPATNQCTIDKNRRKSCQACRLRK 208

Query: 165 CLKVGMLKEGVRLDRVRGGRQKYKRRIDAE------------NSPYLNPQLVQPAKKPYN 212
           C +VGM+K G R +R      + +R  D +            ++P +  +L+  A  P  
Sbjct: 209 CYEVGMVKCGSRRERCGYRLVRRQRSADEQLHCAGKAKRSGGHAPRVR-ELLLDALSP-E 266

Query: 213 KIVSHLLVAEPEKIYAMPDPTVPDSDIKALTTLCDLADRELVVIIGWAKHIPGFSTLSLA 272
           ++V  LL AEP  +  +  P+ P ++   + +L  LAD+ELV +I WAK IPGF  LSL 
Sbjct: 267 QLVLTLLEAEPPHV-LISRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLF 325

Query: 273 DQMSLLQSAWMEILILGVVYRSLSFEDELVYADDYIMDEDQSK-LAGLLDLNNAILQLVK 331
           DQ+ LL+S WME+L++G+++RS+    +L++A D ++D D+ K + G+L++ + +L    
Sbjct: 326 DQVRLLESCWMEVLMMGLMWRSIDHPGKLIFAPDLVLDRDEGKCVEGILEIFDMLLATTS 385

Query: 332 KYKSMKLEKEEFVTLKAIALANSDSMHI----EDVEAVQKLQDVLH 373
           +++ +KL+ +E++ +KA+ L NS    +    +D ++ +KL  +L+
Sbjct: 386 RFRELKLQHKEYLCVKAMILLNSSMYPLVTATQDADSSRKLAHLLN 431


>gi|11415052 retinoid X receptor, beta [Homo sapiens]
          Length = 533

 Score =  209 bits (533), Expect = 3e-54
 Identities = 118/337 (35%), Positives = 185/337 (54%), Gaps = 15/337 (4%)

Query: 102 KRLCLVCGDIASGYHYGVASCEACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQACR 161
           KRLC +CGD +SG HYGV SCE CK FFKRTI+ ++ YSC    +C + KR+R  CQ CR
Sbjct: 202 KRLCAICGDRSSGKHYGVYSCEGCKGFFKRTIRKDLTYSCRDNKDCTVDKRQRNRCQYCR 261

Query: 162 FMKCLKVGMLKEGVRLDRVRGGRQKYKRRIDAENSPYLNPQLVQPAKKPYNKIVSHLLVA 221
           + KCL  GM +E V+ +R RG      +  D E +         P + P ++I+   L  
Sbjct: 262 YQKCLATGMKREAVQEERQRG----KDKDGDGEGAG------GAPEEMPVDRILEAELAV 311

Query: 222 EPEKIYAMPDP----TVPDSDIKALTTLCDLADRELVVIIGWAKHIPGFSTLSLADQMSL 277
           E +    +  P        S    +T +C  AD++L  ++ WAK IP FS+L L DQ+ L
Sbjct: 312 EQKSDQGVEGPGGTGGSGSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSSLPLDDQVIL 371

Query: 278 LQSAWMEILILGVVYRSLSFEDELVYADDYIMDEDQSKLAGLLDLNNAIL-QLVKKYKSM 336
           L++ W E+LI    +RS+   D ++ A    +  + +  AG+  + + +L +LV K + M
Sbjct: 372 LRAGWNELLIASFSHRSIDVRDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDM 431

Query: 337 KLEKEEFVTLKAIALANSDSMHIEDVEAVQKLQDVLHEALQDYEAGQHMEDPRRAGKMLM 396
           +++K E   L+AI L N D+  + +   V+ L++ ++ +L+ Y   ++ E   R  K+L+
Sbjct: 432 RMDKTELGCLRAIILFNPDAKGLSNPSEVEVLREKVYASLETYCKQKYPEQQGRFAKLLL 491

Query: 397 TLPLLRQTSTKAVQHFYNIKLEGKVPMHKLFLEMLEA 433
            LP LR    K ++H +  KL G  P+    +EMLEA
Sbjct: 492 RLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEA 528


>gi|4506423 retinoic acid receptor, gamma isoform 1 [Homo sapiens]
          Length = 454

 Score =  199 bits (507), Expect = 3e-51
 Identities = 134/389 (34%), Positives = 194/389 (49%), Gaps = 21/389 (5%)

Query: 58  SPPLYPSAPILGGSGPVRKLYDDCSSTIVEDPQTKCEYMLNSMPK--------RLCLVCG 109
           SPP    +P   G G    L  + +S  VE   T  E M+ S P         + C VC 
Sbjct: 36  SPPFEMLSPSFRGLGQP-DLPKEMASLSVETQSTSSEEMVPSSPSPPPPPRVYKPCFVCN 94

Query: 110 DIASGYHYGVASCEACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQACRFMKCLKVG 169
           D +SGYHYGV+SCE CK FF+R+IQ N+ Y+C     C I K  R  CQ CR  KC +VG
Sbjct: 95  DKSSGYHYGVSSCEGCKGFFRRSIQKNMVYTCHRDKNCIINKVTRNRCQYCRLQKCFEVG 154

Query: 170 MLKEGVRLDRVRGGRQKYKRRIDAENSP---YLNPQL---VQPAKKPYNKIVSHLLVAEP 223
           M KE VR DR      K K+ +  E SP    L+PQL   +    K + +    L     
Sbjct: 155 MSKEAVRNDR-----NKKKKEVKEEGSPDSYELSPQLEELITKVSKAHQETFPSLCQLGK 209

Query: 224 EKIYAMPDPTVPDSDIKALTTLCDLADRELVVIIGWAKHIPGFSTLSLADQMSLLQSAWM 283
               +  D  V   D+       +LA + ++ I+ +AK +PGF+ LS+ADQ++LL++A +
Sbjct: 210 YTTNSSADHRV-QLDLGLWDKFSELATKCIIKIVEFAKRLPGFTGLSIADQITLLKAACL 268

Query: 284 EILILGVVYRSLSFEDELVYADDYIMDEDQSKLAGLLDLNNAILQLVKKYKSMKLEKEEF 343
           +IL+L +  R    +D + ++D   ++  Q   AG   L + +     +   ++++  E 
Sbjct: 269 DILMLRICTRYTPEQDTMTFSDGLTLNRTQMHNAGFGPLTDLVFAFAGQLLPLEMDDTET 328

Query: 344 VTLKAIALANSDSMHIEDVEAVQKLQDVLHEALQDYEAGQHMEDPRRAGKMLMTLPLLRQ 403
             L AI L   D M +E+ E V KLQ+ L EAL+ Y   +    P    +MLM +  LR 
Sbjct: 329 GLLSAICLICGDRMDLEEPEKVDKLQEPLLEALRLYARRRRPSQPYMFPRMLMKITDLRG 388

Query: 404 TSTKAVQHFYNIKLEGKVPMHKLFLEMLE 432
            STK  +    +K+E   PM  L  EMLE
Sbjct: 389 ISTKGAERAITLKMEIPGPMPPLIREMLE 417


>gi|112181200 retinoic acid receptor, gamma isoform 2 [Homo sapiens]
          Length = 443

 Score =  194 bits (494), Expect = 1e-49
 Identities = 126/361 (34%), Positives = 183/361 (50%), Gaps = 20/361 (5%)

Query: 86  VEDPQTKCEYMLNSMPK--------RLCLVCGDIASGYHYGVASCEACKAFFKRTIQGNI 137
           VE   T  E M+ S P         + C VC D +SGYHYGV+SCE CK FF+R+IQ N+
Sbjct: 52  VETQSTSSEEMVPSSPSPPPPPRVYKPCFVCNDKSSGYHYGVSSCEGCKGFFRRSIQKNM 111

Query: 138 EYSCPATNECEITKRRRKSCQACRFMKCLKVGMLKEGVRLDRVRGGRQKYKRRIDAENSP 197
            Y+C     C I K  R  CQ CR  KC +VGM KE VR DR      K K+ +  E SP
Sbjct: 112 VYTCHRDKNCIINKVTRNRCQYCRLQKCFEVGMSKEAVRNDR-----NKKKKEVKEEGSP 166

Query: 198 ---YLNPQL---VQPAKKPYNKIVSHLLVAEPEKIYAMPDPTVPDSDIKALTTLCDLADR 251
               L+PQL   +    K + +    L         +  D  V   D+       +LA +
Sbjct: 167 DSYELSPQLEELITKVSKAHQETFPSLCQLGKYTTNSSADHRV-QLDLGLWDKFSELATK 225

Query: 252 ELVVIIGWAKHIPGFSTLSLADQMSLLQSAWMEILILGVVYRSLSFEDELVYADDYIMDE 311
            ++ I+ +AK +PGF+ LS+ADQ++LL++A ++IL+L +  R    +D + ++D   ++ 
Sbjct: 226 CIIKIVEFAKRLPGFTGLSIADQITLLKAACLDILMLRICTRYTPEQDTMTFSDGLTLNR 285

Query: 312 DQSKLAGLLDLNNAILQLVKKYKSMKLEKEEFVTLKAIALANSDSMHIEDVEAVQKLQDV 371
            Q   AG   L + +     +   ++++  E   L AI L   D M +E+ E V KLQ+ 
Sbjct: 286 TQMHNAGFGPLTDLVFAFAGQLLPLEMDDTETGLLSAICLICGDRMDLEEPEKVDKLQEP 345

Query: 372 LHEALQDYEAGQHMEDPRRAGKMLMTLPLLRQTSTKAVQHFYNIKLEGKVPMHKLFLEML 431
           L EAL+ Y   +    P    +MLM +  LR  STK  +    +K+E   PM  L  EML
Sbjct: 346 LLEALRLYARRRRPSQPYMFPRMLMKITDLRGISTKGAERAITLKMEIPGPMPPLIREML 405

Query: 432 E 432
           E
Sbjct: 406 E 406


>gi|14149746 nuclear receptor subfamily 2, group F, member 2 isoform
           a [Homo sapiens]
          Length = 414

 Score =  191 bits (486), Expect = 9e-49
 Identities = 110/329 (33%), Positives = 169/329 (51%), Gaps = 9/329 (2%)

Query: 105 CLVCGDIASGYHYGVASCEACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQACRFMK 164
           C+VCGD +SG HYG  +CE CK+FFKR+++ N+ Y+C A   C I +  R  CQ CR  K
Sbjct: 79  CVVCGDKSSGKHYGQFTCEGCKSFFKRSVRRNLSYTCRANRNCPIDQHHRNQCQYCRLKK 138

Query: 165 CLKVGMLKEGVRLDRVRGGRQKYKRRIDAENSPYLNPQLVQPAKKPYNKIVSHLLVAEPE 224
           CLKVGM +E V+  R+    Q    +    N   LN           +  +S LL AEP 
Sbjct: 139 CLKVGMRREAVQRGRM-PPTQPTHGQFALTNGDPLN------CHSYLSGYISLLLRAEPY 191

Query: 225 KIYAMPDPTVPDSDIKALTTLCDLADRELVVIIGWAKHIPGFSTLSLADQMSLLQSAWME 284
                    +  ++I  +  +C+LA R L   + WA++IP F  L + DQ++LL+  W E
Sbjct: 192 PTSRFGSQCMQPNNIMGIENICELAARMLFSAVEWARNIPFFPDLQITDQVALLRLTWSE 251

Query: 285 ILILGVVYRS--LSFEDELVYADDYIMDEDQSKLAGLLDLNNAILQLVKKYKSMKLEKEE 342
           + +L     S  L     L  A  +       ++   +D      + V+K K++ ++  E
Sbjct: 252 LFVLNAAQCSMPLHVAPLLAAAGLHASPMSADRVVAFMDHIRIFQEQVEKLKALHVDSAE 311

Query: 343 FVTLKAIALANSDSMHIEDVEAVQKLQDVLHEALQDYEAGQHMEDPRRAGKMLMTLPLLR 402
           +  LKAI L  SD+  + DV  V+ LQ+    AL++Y   Q+   P R GK+L+ LP LR
Sbjct: 312 YSCLKAIVLFTSDACGLSDVAHVESLQEKSQCALEEYVRSQYPNQPTRFGKLLLRLPSLR 371

Query: 403 QTSTKAVQHFYNIKLEGKVPMHKLFLEML 431
             S+  ++  + ++L GK P+  L  +ML
Sbjct: 372 TVSSSVIEQLFFVRLVGKTPIETLIRDML 400


>gi|5032173 nuclear receptor subfamily 2, group F, member 1 [Homo
           sapiens]
          Length = 423

 Score =  189 bits (480), Expect = 4e-48
 Identities = 109/329 (33%), Positives = 168/329 (51%), Gaps = 9/329 (2%)

Query: 105 CLVCGDIASGYHYGVASCEACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQACRFMK 164
           C+VCGD +SG HYG  +CE CK+FFKR+++ N+ Y+C A   C I +  R  CQ CR  K
Sbjct: 86  CVVCGDKSSGKHYGQFTCEGCKSFFKRSVRRNLTYTCRANRNCPIDQHHRNQCQYCRLKK 145

Query: 165 CLKVGMLKEGVRLDRVRGGRQKYKRRIDAENSPYLNPQLVQPAKKPYNKIVSHLLVAEPE 224
           CLKVGM +E V+  R+    Q    +    N   LN           +  +S LL AEP 
Sbjct: 146 CLKVGMRREAVQRGRM-PPTQPNPGQYALTNGDPLNGHCY------LSGYISLLLRAEPY 198

Query: 225 KIYAMPDPTVPDSDIKALTTLCDLADRELVVIIGWAKHIPGFSTLSLADQMSLLQSAWME 284
                    +  ++I  +  +C+LA R L   + WA++IP F  L + DQ+SLL+  W E
Sbjct: 199 PTSRYGSQCMQPNNIMGIENICELAARLLFSAVEWARNIPFFPDLQITDQVSLLRLTWSE 258

Query: 285 ILILGVVYRS--LSFEDELVYADDYIMDEDQSKLAGLLDLNNAILQLVKKYKSMKLEKEE 342
           + +L     S  L     L  A  +       ++   +D      + V+K K++ ++  E
Sbjct: 259 LFVLNAAQCSMPLHVAPLLAAAGLHASPMSADRVVAFMDHIRIFQEQVEKLKALHVDSAE 318

Query: 343 FVTLKAIALANSDSMHIEDVEAVQKLQDVLHEALQDYEAGQHMEDPRRAGKMLMTLPLLR 402
           +  LKAI L  SD+  + D   ++ LQ+    AL++Y   Q+   P R GK+L+ LP LR
Sbjct: 319 YSCLKAIVLFTSDACGLSDAAHIESLQEKSQCALEEYVRSQYPNQPSRFGKLLLRLPSLR 378

Query: 403 QTSTKAVQHFYNIKLEGKVPMHKLFLEML 431
             S+  ++  + ++L GK P+  L  +ML
Sbjct: 379 TVSSSVIEQLFFVRLVGKTPIETLIRDML 407


>gi|223718064 retinoic acid receptor, alpha isoform 1 [Homo sapiens]
          Length = 462

 Score =  188 bits (477), Expect = 9e-48
 Identities = 129/414 (31%), Positives = 197/414 (47%), Gaps = 26/414 (6%)

Query: 42  SGSYSSTMNGHQNGLDSPPL-YPSAPILGGSGPVRKL-----------YDDCSSTIVEDP 89
           S S  +   GH NG   PP  +   P+LGG  P   L           Y   S   +E  
Sbjct: 5   SSSCPTPGGGHLNGYPVPPYAFFFPPMLGGLSPPGALTTLQHQLPVSGYSTPSPATIETQ 64

Query: 90  QTKCEYMLNSMPK--------RLCLVCGDIASGYHYGVASCEACKAFFKRTIQGNIEYSC 141
            +  E ++ S P         + C VC D +SGYHYGV++CE CK FF+R+IQ N+ Y+C
Sbjct: 65  SSSSEEIVPSPPSPPPLPRIYKPCFVCQDKSSGYHYGVSACEGCKGFFRRSIQKNMVYTC 124

Query: 142 PATNECEITKRRRKSCQACRFMKCLKVGMLKEGVRLDRVRGGRQKYKRRIDAENSPYLNP 201
                C I K  R  CQ CR  KC +VGM KE VR DR +  ++K   + +   S  L P
Sbjct: 125 HRDKNCIINKVTRNRCQYCRLQKCFEVGMSKESVRNDRNK--KKKEVPKPECSESYTLTP 182

Query: 202 ---QLVQPAKKPYNKIVSHLLVAEPEKIYAMPDPTVPDSDIKALTTLCDLADRELVVIIG 258
              +L++  +K + +    L            +  V   DI       +L+ + ++  + 
Sbjct: 183 EVGELIEKVRKAHQETFPALCQLGKYTTNNSSEQRV-SLDIDLWDKFSELSTKCIIKTVE 241

Query: 259 WAKHIPGFSTLSLADQMSLLQSAWMEILILGVVYRSLSFEDELVYADDYIMDEDQSKLAG 318
           +AK +PGF+TL++ADQ++LL++A ++ILIL +  R    +D + ++D   ++  Q   AG
Sbjct: 242 FAKQLPGFTTLTIADQITLLKAACLDILILRICTRYTPEQDTMTFSDGLTLNRTQMHNAG 301

Query: 319 LLDLNNAILQLVKKYKSMKLEKEEFVTLKAIALANSDSMHIEDVEAVQKLQDVLHEALQD 378
              L + +     +   ++++  E   L AI L   D   +E  + V  LQ+ L EAL+ 
Sbjct: 302 FGPLTDLVFAFANQLLPLEMDDAETGLLSAICLICGDRQDLEQPDRVDMLQEPLLEALKV 361

Query: 379 YEAGQHMEDPRRAGKMLMTLPLLRQTSTKAVQHFYNIKLEGKVPMHKLFLEMLE 432
           Y   +    P    KMLM +  LR  S K  +    +K+E    M  L  EMLE
Sbjct: 362 YVRKRRPSRPHMFPKMLMKITDLRSISAKGAERVITLKMEIPGSMPPLIQEMLE 415


>gi|4506419 retinoic acid receptor, alpha isoform 1 [Homo sapiens]
          Length = 462

 Score =  188 bits (477), Expect = 9e-48
 Identities = 129/414 (31%), Positives = 197/414 (47%), Gaps = 26/414 (6%)

Query: 42  SGSYSSTMNGHQNGLDSPPL-YPSAPILGGSGPVRKL-----------YDDCSSTIVEDP 89
           S S  +   GH NG   PP  +   P+LGG  P   L           Y   S   +E  
Sbjct: 5   SSSCPTPGGGHLNGYPVPPYAFFFPPMLGGLSPPGALTTLQHQLPVSGYSTPSPATIETQ 64

Query: 90  QTKCEYMLNSMPK--------RLCLVCGDIASGYHYGVASCEACKAFFKRTIQGNIEYSC 141
            +  E ++ S P         + C VC D +SGYHYGV++CE CK FF+R+IQ N+ Y+C
Sbjct: 65  SSSSEEIVPSPPSPPPLPRIYKPCFVCQDKSSGYHYGVSACEGCKGFFRRSIQKNMVYTC 124

Query: 142 PATNECEITKRRRKSCQACRFMKCLKVGMLKEGVRLDRVRGGRQKYKRRIDAENSPYLNP 201
                C I K  R  CQ CR  KC +VGM KE VR DR +  ++K   + +   S  L P
Sbjct: 125 HRDKNCIINKVTRNRCQYCRLQKCFEVGMSKESVRNDRNK--KKKEVPKPECSESYTLTP 182

Query: 202 ---QLVQPAKKPYNKIVSHLLVAEPEKIYAMPDPTVPDSDIKALTTLCDLADRELVVIIG 258
              +L++  +K + +    L            +  V   DI       +L+ + ++  + 
Sbjct: 183 EVGELIEKVRKAHQETFPALCQLGKYTTNNSSEQRV-SLDIDLWDKFSELSTKCIIKTVE 241

Query: 259 WAKHIPGFSTLSLADQMSLLQSAWMEILILGVVYRSLSFEDELVYADDYIMDEDQSKLAG 318
           +AK +PGF+TL++ADQ++LL++A ++ILIL +  R    +D + ++D   ++  Q   AG
Sbjct: 242 FAKQLPGFTTLTIADQITLLKAACLDILILRICTRYTPEQDTMTFSDGLTLNRTQMHNAG 301

Query: 319 LLDLNNAILQLVKKYKSMKLEKEEFVTLKAIALANSDSMHIEDVEAVQKLQDVLHEALQD 378
              L + +     +   ++++  E   L AI L   D   +E  + V  LQ+ L EAL+ 
Sbjct: 302 FGPLTDLVFAFANQLLPLEMDDAETGLLSAICLICGDRQDLEQPDRVDMLQEPLLEALKV 361

Query: 379 YEAGQHMEDPRRAGKMLMTLPLLRQTSTKAVQHFYNIKLEGKVPMHKLFLEMLE 432
           Y   +    P    KMLM +  LR  S K  +    +K+E    M  L  EMLE
Sbjct: 362 YVRKRRPSRPHMFPKMLMKITDLRSISAKGAERVITLKMEIPGSMPPLIQEMLE 415


>gi|5453822 nuclear receptor subfamily 4, group A, member 2 [Homo
           sapiens]
          Length = 598

 Score =  187 bits (475), Expect = 2e-47
 Identities = 114/337 (33%), Positives = 182/337 (54%), Gaps = 11/337 (3%)

Query: 104 LCLVCGDIASGYHYGVASCEACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQACRFM 163
           LC VCGD A+  HYGV +CE CK FFKRT+Q N +Y C A   C + KRRR  CQ CRF 
Sbjct: 262 LCAVCGDNAACQHYGVRTCEGCKGFFKRTVQKNAKYVCLANKNCPVDKRRRNRCQYCRFQ 321

Query: 164 KCLKVGMLKEGVRLDRVRG--GRQKYKRRIDAENSPYLNP-QLVQPAKKPYNKIVSHLLV 220
           KCL VGM+KE VR D ++G  GR   K +   E SP   P  L+    + +      +  
Sbjct: 322 KCLAVGMVKEVVRTDSLKGRRGRLPSKPKSPQEPSPPSPPVSLISALVRAHVDSNPAMTS 381

Query: 221 AEPEKIYAMPDPTVPDSDIKALTTLCDLADRELVVIIGWAKHIPGFSTLSLADQMSLLQS 280
            +  +  A PD  +   D + +    DL    + +I GWA+ IPGF+ L  ADQ  L +S
Sbjct: 382 LDYSRFQANPDYQMSGDDTQHIQQFYDLLTGSMEIIRGWAEKIPGFADLPKADQDLLFES 441

Query: 281 AWMEILILGVVYRSLSFEDELVYADDYIMDEDQSKLAGLLDLNNAILQLVKKYKSMKLEK 340
           A++E+ +L + YRS   E +L++ +  ++   Q  + G  +  ++I++     ++M ++ 
Sbjct: 442 AFLELFVLRLAYRSNPVEGKLIFCNGVVLHRLQC-VRGFGEWIDSIVEFSSNLQNMNIDI 500

Query: 341 EEFVTLKAIALANSDSMHIEDVEAVQKLQDVLHEALQDYEAGQH--MEDPRRAGKMLMTL 398
             F  + A+A+  ++   +++ + V++LQ+ +   L+D+    +  +  P    K+L  L
Sbjct: 501 SAFSCIAALAMV-TERHGLKEPKRVEELQNKIVNCLKDHVTFNNGGLNRPNYLSKLLGKL 559

Query: 399 PLLRQTSTKAVQHFYNIKLEGKVP----MHKLFLEML 431
           P LR   T+ +Q  + +KLE  VP    + KLFL+ L
Sbjct: 560 PELRTLCTQGLQRIFYLKLEDLVPPPAIIDKLFLDTL 596


>gi|67459914 retinoic acid receptor, alpha isoform 2 [Homo sapiens]
          Length = 457

 Score =  181 bits (458), Expect = 2e-45
 Identities = 121/386 (31%), Positives = 187/386 (48%), Gaps = 12/386 (3%)

Query: 53  QNGLDSPPLYPS---APILGGSGPVRKLYDDCSSTIVEDPQTKCEYMLNSMPKRLCLVCG 109
           + GL +P  Y +    P+  GS    +     S  IV  P +         P   C VC 
Sbjct: 31  EKGLPAPGPYSTPLRTPLWNGSNHSIETQSSSSEEIVPSPPSPPPLPRIYKP---CFVCQ 87

Query: 110 DIASGYHYGVASCEACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQACRFMKCLKVG 169
           D +SGYHYGV++CE CK FF+R+IQ N+ Y+C     C I K  R  CQ CR  KC +VG
Sbjct: 88  DKSSGYHYGVSACEGCKGFFRRSIQKNMVYTCHRDKNCIINKVTRNRCQYCRLQKCFEVG 147

Query: 170 MLKEGVRLDRVRGGRQKYKRRIDAENSPYLNP---QLVQPAKKPYNKIVSHLLVAEPEKI 226
           M KE VR DR +  ++K   + +   S  L P   +L++  +K + +    L        
Sbjct: 148 MSKESVRNDRNK--KKKEVPKPECSESYTLTPEVGELIEKVRKAHQETFPALCQLGKYTT 205

Query: 227 YAMPDPTVPDSDIKALTTLCDLADRELVVIIGWAKHIPGFSTLSLADQMSLLQSAWMEIL 286
               +  V   DI       +L+ + ++  + +AK +PGF+TL++ADQ++LL++A ++IL
Sbjct: 206 NNSSEQRV-SLDIDLWDKFSELSTKCIIKTVEFAKQLPGFTTLTIADQITLLKAACLDIL 264

Query: 287 ILGVVYRSLSFEDELVYADDYIMDEDQSKLAGLLDLNNAILQLVKKYKSMKLEKEEFVTL 346
           IL +  R    +D + ++D   ++  Q   AG   L + +     +   ++++  E   L
Sbjct: 265 ILRICTRYTPEQDTMTFSDGLTLNRTQMHNAGFGPLTDLVFAFANQLLPLEMDDAETGLL 324

Query: 347 KAIALANSDSMHIEDVEAVQKLQDVLHEALQDYEAGQHMEDPRRAGKMLMTLPLLRQTST 406
            AI L   D   +E  + V  LQ+ L EAL+ Y   +    P    KMLM +  LR  S 
Sbjct: 325 SAICLICGDRQDLEQPDRVDMLQEPLLEALKVYVRKRRPSRPHMFPKMLMKITDLRSISA 384

Query: 407 KAVQHFYNIKLEGKVPMHKLFLEMLE 432
           K  +    +K+E    M  L  EMLE
Sbjct: 385 KGAERVITLKMEIPGSMPPLIQEMLE 410


>gi|66528642 nuclear receptor subfamily 3, group C, member 1 isoform
           beta [Homo sapiens]
          Length = 742

 Score =  180 bits (457), Expect = 2e-45
 Identities = 102/273 (37%), Positives = 150/273 (54%), Gaps = 4/273 (1%)

Query: 86  VEDPQTKCEYMLNSMPKRLCLVCGDIASGYHYGVASCEACKAFFKRTIQGNIEYSCPATN 145
           V  P +         P +LCLVC D ASG HYGV +C +CK FFKR ++G   Y C   N
Sbjct: 402 VSSPPSSSSTATTGPPPKLCLVCSDEASGCHYGVLTCGSCKVFFKRAVEGQHNYLCAGRN 461

Query: 146 ECEITKRRRKSCQACRFMKCLKVGMLKEGVRLDRVRGGRQKYKRRIDAENSPYLNPQLVQ 205
           +C I K RRK+C ACR+ KCL+ GM  E  +  +   G Q+    +  E S     + + 
Sbjct: 462 DCIIDKIRRKNCPACRYRKCLQAGMNLEARKTKKKIKGIQQATTGVSQETSENPGNKTIV 521

Query: 206 PAKKPY--NKIVSHLLVAEPEKIYAMPDPTVPDSDIKALTTLCDLADRELVVIIGWAKHI 263
           PA  P     +VS L V EPE +YA  D +VPDS  + +TTL  L  R+++  + WAK I
Sbjct: 522 PATLPQLTPTLVSLLEVIEPEVLYAGYDSSVPDSTWRIMTTLNMLGGRQVIAAVKWAKAI 581

Query: 264 PGFSTLSLADQMSLLQSAWMEILILGVVYRSL--SFEDELVYADDYIMDEDQSKLAGLLD 321
           PGF  L L DQM+LLQ +WM ++   + +RS   S  + L +A D I++E +  L  + D
Sbjct: 582 PGFRNLHLDDQMTLLQYSWMFLMAFALGWRSYRQSSANLLCFAPDLIINEQRMTLPCMYD 641

Query: 322 LNNAILQLVKKYKSMKLEKEEFVTLKAIALANS 354
               +L +  +   +++  EE++ +K + L +S
Sbjct: 642 QCKHMLYVSSELHRLQVSYEEYLCMKTLLLLSS 674


>gi|66528611 nuclear receptor subfamily 3, group C, member 1 isoform
           alpha [Homo sapiens]
          Length = 777

 Score =  180 bits (457), Expect = 2e-45
 Identities = 102/273 (37%), Positives = 150/273 (54%), Gaps = 4/273 (1%)

Query: 86  VEDPQTKCEYMLNSMPKRLCLVCGDIASGYHYGVASCEACKAFFKRTIQGNIEYSCPATN 145
           V  P +         P +LCLVC D ASG HYGV +C +CK FFKR ++G   Y C   N
Sbjct: 402 VSSPPSSSSTATTGPPPKLCLVCSDEASGCHYGVLTCGSCKVFFKRAVEGQHNYLCAGRN 461

Query: 146 ECEITKRRRKSCQACRFMKCLKVGMLKEGVRLDRVRGGRQKYKRRIDAENSPYLNPQLVQ 205
           +C I K RRK+C ACR+ KCL+ GM  E  +  +   G Q+    +  E S     + + 
Sbjct: 462 DCIIDKIRRKNCPACRYRKCLQAGMNLEARKTKKKIKGIQQATTGVSQETSENPGNKTIV 521

Query: 206 PAKKPY--NKIVSHLLVAEPEKIYAMPDPTVPDSDIKALTTLCDLADRELVVIIGWAKHI 263
           PA  P     +VS L V EPE +YA  D +VPDS  + +TTL  L  R+++  + WAK I
Sbjct: 522 PATLPQLTPTLVSLLEVIEPEVLYAGYDSSVPDSTWRIMTTLNMLGGRQVIAAVKWAKAI 581

Query: 264 PGFSTLSLADQMSLLQSAWMEILILGVVYRSL--SFEDELVYADDYIMDEDQSKLAGLLD 321
           PGF  L L DQM+LLQ +WM ++   + +RS   S  + L +A D I++E +  L  + D
Sbjct: 582 PGFRNLHLDDQMTLLQYSWMFLMAFALGWRSYRQSSANLLCFAPDLIINEQRMTLPCMYD 641

Query: 322 LNNAILQLVKKYKSMKLEKEEFVTLKAIALANS 354
               +L +  +   +++  EE++ +K + L +S
Sbjct: 642 QCKHMLYVSSELHRLQVSYEEYLCMKTLLLLSS 674


>gi|66528586 nuclear receptor subfamily 3, group C, member 1 isoform
           alpha [Homo sapiens]
          Length = 777

 Score =  180 bits (457), Expect = 2e-45
 Identities = 102/273 (37%), Positives = 150/273 (54%), Gaps = 4/273 (1%)

Query: 86  VEDPQTKCEYMLNSMPKRLCLVCGDIASGYHYGVASCEACKAFFKRTIQGNIEYSCPATN 145
           V  P +         P +LCLVC D ASG HYGV +C +CK FFKR ++G   Y C   N
Sbjct: 402 VSSPPSSSSTATTGPPPKLCLVCSDEASGCHYGVLTCGSCKVFFKRAVEGQHNYLCAGRN 461

Query: 146 ECEITKRRRKSCQACRFMKCLKVGMLKEGVRLDRVRGGRQKYKRRIDAENSPYLNPQLVQ 205
           +C I K RRK+C ACR+ KCL+ GM  E  +  +   G Q+    +  E S     + + 
Sbjct: 462 DCIIDKIRRKNCPACRYRKCLQAGMNLEARKTKKKIKGIQQATTGVSQETSENPGNKTIV 521

Query: 206 PAKKPY--NKIVSHLLVAEPEKIYAMPDPTVPDSDIKALTTLCDLADRELVVIIGWAKHI 263
           PA  P     +VS L V EPE +YA  D +VPDS  + +TTL  L  R+++  + WAK I
Sbjct: 522 PATLPQLTPTLVSLLEVIEPEVLYAGYDSSVPDSTWRIMTTLNMLGGRQVIAAVKWAKAI 581

Query: 264 PGFSTLSLADQMSLLQSAWMEILILGVVYRSL--SFEDELVYADDYIMDEDQSKLAGLLD 321
           PGF  L L DQM+LLQ +WM ++   + +RS   S  + L +A D I++E +  L  + D
Sbjct: 582 PGFRNLHLDDQMTLLQYSWMFLMAFALGWRSYRQSSANLLCFAPDLIINEQRMTLPCMYD 641

Query: 322 LNNAILQLVKKYKSMKLEKEEFVTLKAIALANS 354
               +L +  +   +++  EE++ +K + L +S
Sbjct: 642 QCKHMLYVSSELHRLQVSYEEYLCMKTLLLLSS 674


>gi|66528563 nuclear receptor subfamily 3, group C, member 1 isoform
           alpha [Homo sapiens]
          Length = 777

 Score =  180 bits (457), Expect = 2e-45
 Identities = 102/273 (37%), Positives = 150/273 (54%), Gaps = 4/273 (1%)

Query: 86  VEDPQTKCEYMLNSMPKRLCLVCGDIASGYHYGVASCEACKAFFKRTIQGNIEYSCPATN 145
           V  P +         P +LCLVC D ASG HYGV +C +CK FFKR ++G   Y C   N
Sbjct: 402 VSSPPSSSSTATTGPPPKLCLVCSDEASGCHYGVLTCGSCKVFFKRAVEGQHNYLCAGRN 461

Query: 146 ECEITKRRRKSCQACRFMKCLKVGMLKEGVRLDRVRGGRQKYKRRIDAENSPYLNPQLVQ 205
           +C I K RRK+C ACR+ KCL+ GM  E  +  +   G Q+    +  E S     + + 
Sbjct: 462 DCIIDKIRRKNCPACRYRKCLQAGMNLEARKTKKKIKGIQQATTGVSQETSENPGNKTIV 521

Query: 206 PAKKPY--NKIVSHLLVAEPEKIYAMPDPTVPDSDIKALTTLCDLADRELVVIIGWAKHI 263
           PA  P     +VS L V EPE +YA  D +VPDS  + +TTL  L  R+++  + WAK I
Sbjct: 522 PATLPQLTPTLVSLLEVIEPEVLYAGYDSSVPDSTWRIMTTLNMLGGRQVIAAVKWAKAI 581

Query: 264 PGFSTLSLADQMSLLQSAWMEILILGVVYRSL--SFEDELVYADDYIMDEDQSKLAGLLD 321
           PGF  L L DQM+LLQ +WM ++   + +RS   S  + L +A D I++E +  L  + D
Sbjct: 582 PGFRNLHLDDQMTLLQYSWMFLMAFALGWRSYRQSSANLLCFAPDLIINEQRMTLPCMYD 641

Query: 322 LNNAILQLVKKYKSMKLEKEEFVTLKAIALANS 354
               +L +  +   +++  EE++ +K + L +S
Sbjct: 642 QCKHMLYVSSELHRLQVSYEEYLCMKTLLLLSS 674


>gi|66528530 nuclear receptor subfamily 3, group C, member 1 isoform
           alpha [Homo sapiens]
          Length = 777

 Score =  180 bits (457), Expect = 2e-45
 Identities = 102/273 (37%), Positives = 150/273 (54%), Gaps = 4/273 (1%)

Query: 86  VEDPQTKCEYMLNSMPKRLCLVCGDIASGYHYGVASCEACKAFFKRTIQGNIEYSCPATN 145
           V  P +         P +LCLVC D ASG HYGV +C +CK FFKR ++G   Y C   N
Sbjct: 402 VSSPPSSSSTATTGPPPKLCLVCSDEASGCHYGVLTCGSCKVFFKRAVEGQHNYLCAGRN 461

Query: 146 ECEITKRRRKSCQACRFMKCLKVGMLKEGVRLDRVRGGRQKYKRRIDAENSPYLNPQLVQ 205
           +C I K RRK+C ACR+ KCL+ GM  E  +  +   G Q+    +  E S     + + 
Sbjct: 462 DCIIDKIRRKNCPACRYRKCLQAGMNLEARKTKKKIKGIQQATTGVSQETSENPGNKTIV 521

Query: 206 PAKKPY--NKIVSHLLVAEPEKIYAMPDPTVPDSDIKALTTLCDLADRELVVIIGWAKHI 263
           PA  P     +VS L V EPE +YA  D +VPDS  + +TTL  L  R+++  + WAK I
Sbjct: 522 PATLPQLTPTLVSLLEVIEPEVLYAGYDSSVPDSTWRIMTTLNMLGGRQVIAAVKWAKAI 581

Query: 264 PGFSTLSLADQMSLLQSAWMEILILGVVYRSL--SFEDELVYADDYIMDEDQSKLAGLLD 321
           PGF  L L DQM+LLQ +WM ++   + +RS   S  + L +A D I++E +  L  + D
Sbjct: 582 PGFRNLHLDDQMTLLQYSWMFLMAFALGWRSYRQSSANLLCFAPDLIINEQRMTLPCMYD 641

Query: 322 LNNAILQLVKKYKSMKLEKEEFVTLKAIALANS 354
               +L +  +   +++  EE++ +K + L +S
Sbjct: 642 QCKHMLYVSSELHRLQVSYEEYLCMKTLLLLSS 674


>gi|4504133 nuclear receptor subfamily 3, group C, member 1 isoform
           alpha [Homo sapiens]
          Length = 777

 Score =  180 bits (457), Expect = 2e-45
 Identities = 102/273 (37%), Positives = 150/273 (54%), Gaps = 4/273 (1%)

Query: 86  VEDPQTKCEYMLNSMPKRLCLVCGDIASGYHYGVASCEACKAFFKRTIQGNIEYSCPATN 145
           V  P +         P +LCLVC D ASG HYGV +C +CK FFKR ++G   Y C   N
Sbjct: 402 VSSPPSSSSTATTGPPPKLCLVCSDEASGCHYGVLTCGSCKVFFKRAVEGQHNYLCAGRN 461

Query: 146 ECEITKRRRKSCQACRFMKCLKVGMLKEGVRLDRVRGGRQKYKRRIDAENSPYLNPQLVQ 205
           +C I K RRK+C ACR+ KCL+ GM  E  +  +   G Q+    +  E S     + + 
Sbjct: 462 DCIIDKIRRKNCPACRYRKCLQAGMNLEARKTKKKIKGIQQATTGVSQETSENPGNKTIV 521

Query: 206 PAKKPY--NKIVSHLLVAEPEKIYAMPDPTVPDSDIKALTTLCDLADRELVVIIGWAKHI 263
           PA  P     +VS L V EPE +YA  D +VPDS  + +TTL  L  R+++  + WAK I
Sbjct: 522 PATLPQLTPTLVSLLEVIEPEVLYAGYDSSVPDSTWRIMTTLNMLGGRQVIAAVKWAKAI 581

Query: 264 PGFSTLSLADQMSLLQSAWMEILILGVVYRSL--SFEDELVYADDYIMDEDQSKLAGLLD 321
           PGF  L L DQM+LLQ +WM ++   + +RS   S  + L +A D I++E +  L  + D
Sbjct: 582 PGFRNLHLDDQMTLLQYSWMFLMAFALGWRSYRQSSANLLCFAPDLIINEQRMTLPCMYD 641

Query: 322 LNNAILQLVKKYKSMKLEKEEFVTLKAIALANS 354
               +L +  +   +++  EE++ +K + L +S
Sbjct: 642 QCKHMLYVSSELHRLQVSYEEYLCMKTLLLLSS 674


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.133    0.389 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,182,042
Number of Sequences: 37866
Number of extensions: 802511
Number of successful extensions: 3032
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 127
Number of HSP's successfully gapped in prelim test: 32
Number of HSP's that attempted gapping in prelim test: 2625
Number of HSP's gapped (non-prelim): 285
length of query: 435
length of database: 18,247,518
effective HSP length: 105
effective length of query: 330
effective length of database: 14,271,588
effective search space: 4709624040
effective search space used: 4709624040
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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