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Search of human proteins with 45545427
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|45545427 estrogen-related receptor gamma isoform 2 [Homo
sapiens]
(435 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|45545429 estrogen-related receptor gamma isoform 2 [Homo sapi... 877 0.0
gi|45545427 estrogen-related receptor gamma isoform 2 [Homo sapi... 877 0.0
gi|45545433 estrogen-related receptor gamma isoform 1 [Homo sapi... 877 0.0
gi|197209821 estrogen-related receptor gamma isoform 2 [Homo sap... 877 0.0
gi|238550159 estrogen-related receptor beta [Homo sapiens] 697 0.0
gi|18860920 estrogen-related receptor alpha [Homo sapiens] 476 e-134
gi|170295804 estrogen receptor alpha isoform 4 [Homo sapiens] 263 2e-70
gi|170295802 estrogen receptor alpha isoform 3 [Homo sapiens] 263 2e-70
gi|170295800 estrogen receptor alpha isoform 2 [Homo sapiens] 263 2e-70
gi|62821794 estrogen receptor alpha isoform 1 [Homo sapiens] 263 2e-70
gi|10835013 estrogen receptor beta isoform 1 [Homo sapiens] 242 6e-64
gi|4506755 retinoid X receptor, alpha [Homo sapiens] 219 3e-57
gi|5902068 retinoid X receptor, gamma isoform a [Homo sapiens] 218 7e-57
gi|94538328 estrogen receptor beta isoform 2 [Homo sapiens] 217 2e-56
gi|94538325 estrogen receptor beta isoform 2 [Homo sapiens] 217 2e-56
gi|11415052 retinoid X receptor, beta [Homo sapiens] 209 3e-54
gi|4506423 retinoic acid receptor, gamma isoform 1 [Homo sapiens] 199 3e-51
gi|112181200 retinoic acid receptor, gamma isoform 2 [Homo sapiens] 194 1e-49
gi|14149746 nuclear receptor subfamily 2, group F, member 2 isof... 191 9e-49
gi|5032173 nuclear receptor subfamily 2, group F, member 1 [Homo... 189 4e-48
gi|223718064 retinoic acid receptor, alpha isoform 1 [Homo sapiens] 188 9e-48
gi|4506419 retinoic acid receptor, alpha isoform 1 [Homo sapiens] 188 9e-48
gi|5453822 nuclear receptor subfamily 4, group A, member 2 [Homo... 187 2e-47
gi|67459914 retinoic acid receptor, alpha isoform 2 [Homo sapiens] 181 2e-45
gi|66528642 nuclear receptor subfamily 3, group C, member 1 isof... 180 2e-45
gi|66528611 nuclear receptor subfamily 3, group C, member 1 isof... 180 2e-45
gi|66528586 nuclear receptor subfamily 3, group C, member 1 isof... 180 2e-45
gi|66528563 nuclear receptor subfamily 3, group C, member 1 isof... 180 2e-45
gi|66528530 nuclear receptor subfamily 3, group C, member 1 isof... 180 2e-45
gi|4504133 nuclear receptor subfamily 3, group C, member 1 isofo... 180 2e-45
>gi|45545429 estrogen-related receptor gamma isoform 2 [Homo
sapiens]
Length = 435
Score = 877 bits (2265), Expect = 0.0
Identities = 435/435 (100%), Positives = 435/435 (100%)
Query: 1 MSNKDRHIDSSCSSFIKTEPSSPASLTDSVNHHSPGGSSDASGSYSSTMNGHQNGLDSPP 60
MSNKDRHIDSSCSSFIKTEPSSPASLTDSVNHHSPGGSSDASGSYSSTMNGHQNGLDSPP
Sbjct: 1 MSNKDRHIDSSCSSFIKTEPSSPASLTDSVNHHSPGGSSDASGSYSSTMNGHQNGLDSPP 60
Query: 61 LYPSAPILGGSGPVRKLYDDCSSTIVEDPQTKCEYMLNSMPKRLCLVCGDIASGYHYGVA 120
LYPSAPILGGSGPVRKLYDDCSSTIVEDPQTKCEYMLNSMPKRLCLVCGDIASGYHYGVA
Sbjct: 61 LYPSAPILGGSGPVRKLYDDCSSTIVEDPQTKCEYMLNSMPKRLCLVCGDIASGYHYGVA 120
Query: 121 SCEACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQACRFMKCLKVGMLKEGVRLDRV 180
SCEACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQACRFMKCLKVGMLKEGVRLDRV
Sbjct: 121 SCEACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQACRFMKCLKVGMLKEGVRLDRV 180
Query: 181 RGGRQKYKRRIDAENSPYLNPQLVQPAKKPYNKIVSHLLVAEPEKIYAMPDPTVPDSDIK 240
RGGRQKYKRRIDAENSPYLNPQLVQPAKKPYNKIVSHLLVAEPEKIYAMPDPTVPDSDIK
Sbjct: 181 RGGRQKYKRRIDAENSPYLNPQLVQPAKKPYNKIVSHLLVAEPEKIYAMPDPTVPDSDIK 240
Query: 241 ALTTLCDLADRELVVIIGWAKHIPGFSTLSLADQMSLLQSAWMEILILGVVYRSLSFEDE 300
ALTTLCDLADRELVVIIGWAKHIPGFSTLSLADQMSLLQSAWMEILILGVVYRSLSFEDE
Sbjct: 241 ALTTLCDLADRELVVIIGWAKHIPGFSTLSLADQMSLLQSAWMEILILGVVYRSLSFEDE 300
Query: 301 LVYADDYIMDEDQSKLAGLLDLNNAILQLVKKYKSMKLEKEEFVTLKAIALANSDSMHIE 360
LVYADDYIMDEDQSKLAGLLDLNNAILQLVKKYKSMKLEKEEFVTLKAIALANSDSMHIE
Sbjct: 301 LVYADDYIMDEDQSKLAGLLDLNNAILQLVKKYKSMKLEKEEFVTLKAIALANSDSMHIE 360
Query: 361 DVEAVQKLQDVLHEALQDYEAGQHMEDPRRAGKMLMTLPLLRQTSTKAVQHFYNIKLEGK 420
DVEAVQKLQDVLHEALQDYEAGQHMEDPRRAGKMLMTLPLLRQTSTKAVQHFYNIKLEGK
Sbjct: 361 DVEAVQKLQDVLHEALQDYEAGQHMEDPRRAGKMLMTLPLLRQTSTKAVQHFYNIKLEGK 420
Query: 421 VPMHKLFLEMLEAKV 435
VPMHKLFLEMLEAKV
Sbjct: 421 VPMHKLFLEMLEAKV 435
>gi|45545427 estrogen-related receptor gamma isoform 2 [Homo
sapiens]
Length = 435
Score = 877 bits (2265), Expect = 0.0
Identities = 435/435 (100%), Positives = 435/435 (100%)
Query: 1 MSNKDRHIDSSCSSFIKTEPSSPASLTDSVNHHSPGGSSDASGSYSSTMNGHQNGLDSPP 60
MSNKDRHIDSSCSSFIKTEPSSPASLTDSVNHHSPGGSSDASGSYSSTMNGHQNGLDSPP
Sbjct: 1 MSNKDRHIDSSCSSFIKTEPSSPASLTDSVNHHSPGGSSDASGSYSSTMNGHQNGLDSPP 60
Query: 61 LYPSAPILGGSGPVRKLYDDCSSTIVEDPQTKCEYMLNSMPKRLCLVCGDIASGYHYGVA 120
LYPSAPILGGSGPVRKLYDDCSSTIVEDPQTKCEYMLNSMPKRLCLVCGDIASGYHYGVA
Sbjct: 61 LYPSAPILGGSGPVRKLYDDCSSTIVEDPQTKCEYMLNSMPKRLCLVCGDIASGYHYGVA 120
Query: 121 SCEACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQACRFMKCLKVGMLKEGVRLDRV 180
SCEACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQACRFMKCLKVGMLKEGVRLDRV
Sbjct: 121 SCEACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQACRFMKCLKVGMLKEGVRLDRV 180
Query: 181 RGGRQKYKRRIDAENSPYLNPQLVQPAKKPYNKIVSHLLVAEPEKIYAMPDPTVPDSDIK 240
RGGRQKYKRRIDAENSPYLNPQLVQPAKKPYNKIVSHLLVAEPEKIYAMPDPTVPDSDIK
Sbjct: 181 RGGRQKYKRRIDAENSPYLNPQLVQPAKKPYNKIVSHLLVAEPEKIYAMPDPTVPDSDIK 240
Query: 241 ALTTLCDLADRELVVIIGWAKHIPGFSTLSLADQMSLLQSAWMEILILGVVYRSLSFEDE 300
ALTTLCDLADRELVVIIGWAKHIPGFSTLSLADQMSLLQSAWMEILILGVVYRSLSFEDE
Sbjct: 241 ALTTLCDLADRELVVIIGWAKHIPGFSTLSLADQMSLLQSAWMEILILGVVYRSLSFEDE 300
Query: 301 LVYADDYIMDEDQSKLAGLLDLNNAILQLVKKYKSMKLEKEEFVTLKAIALANSDSMHIE 360
LVYADDYIMDEDQSKLAGLLDLNNAILQLVKKYKSMKLEKEEFVTLKAIALANSDSMHIE
Sbjct: 301 LVYADDYIMDEDQSKLAGLLDLNNAILQLVKKYKSMKLEKEEFVTLKAIALANSDSMHIE 360
Query: 361 DVEAVQKLQDVLHEALQDYEAGQHMEDPRRAGKMLMTLPLLRQTSTKAVQHFYNIKLEGK 420
DVEAVQKLQDVLHEALQDYEAGQHMEDPRRAGKMLMTLPLLRQTSTKAVQHFYNIKLEGK
Sbjct: 361 DVEAVQKLQDVLHEALQDYEAGQHMEDPRRAGKMLMTLPLLRQTSTKAVQHFYNIKLEGK 420
Query: 421 VPMHKLFLEMLEAKV 435
VPMHKLFLEMLEAKV
Sbjct: 421 VPMHKLFLEMLEAKV 435
>gi|45545433 estrogen-related receptor gamma isoform 1 [Homo
sapiens]
Length = 458
Score = 877 bits (2265), Expect = 0.0
Identities = 435/435 (100%), Positives = 435/435 (100%)
Query: 1 MSNKDRHIDSSCSSFIKTEPSSPASLTDSVNHHSPGGSSDASGSYSSTMNGHQNGLDSPP 60
MSNKDRHIDSSCSSFIKTEPSSPASLTDSVNHHSPGGSSDASGSYSSTMNGHQNGLDSPP
Sbjct: 24 MSNKDRHIDSSCSSFIKTEPSSPASLTDSVNHHSPGGSSDASGSYSSTMNGHQNGLDSPP 83
Query: 61 LYPSAPILGGSGPVRKLYDDCSSTIVEDPQTKCEYMLNSMPKRLCLVCGDIASGYHYGVA 120
LYPSAPILGGSGPVRKLYDDCSSTIVEDPQTKCEYMLNSMPKRLCLVCGDIASGYHYGVA
Sbjct: 84 LYPSAPILGGSGPVRKLYDDCSSTIVEDPQTKCEYMLNSMPKRLCLVCGDIASGYHYGVA 143
Query: 121 SCEACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQACRFMKCLKVGMLKEGVRLDRV 180
SCEACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQACRFMKCLKVGMLKEGVRLDRV
Sbjct: 144 SCEACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQACRFMKCLKVGMLKEGVRLDRV 203
Query: 181 RGGRQKYKRRIDAENSPYLNPQLVQPAKKPYNKIVSHLLVAEPEKIYAMPDPTVPDSDIK 240
RGGRQKYKRRIDAENSPYLNPQLVQPAKKPYNKIVSHLLVAEPEKIYAMPDPTVPDSDIK
Sbjct: 204 RGGRQKYKRRIDAENSPYLNPQLVQPAKKPYNKIVSHLLVAEPEKIYAMPDPTVPDSDIK 263
Query: 241 ALTTLCDLADRELVVIIGWAKHIPGFSTLSLADQMSLLQSAWMEILILGVVYRSLSFEDE 300
ALTTLCDLADRELVVIIGWAKHIPGFSTLSLADQMSLLQSAWMEILILGVVYRSLSFEDE
Sbjct: 264 ALTTLCDLADRELVVIIGWAKHIPGFSTLSLADQMSLLQSAWMEILILGVVYRSLSFEDE 323
Query: 301 LVYADDYIMDEDQSKLAGLLDLNNAILQLVKKYKSMKLEKEEFVTLKAIALANSDSMHIE 360
LVYADDYIMDEDQSKLAGLLDLNNAILQLVKKYKSMKLEKEEFVTLKAIALANSDSMHIE
Sbjct: 324 LVYADDYIMDEDQSKLAGLLDLNNAILQLVKKYKSMKLEKEEFVTLKAIALANSDSMHIE 383
Query: 361 DVEAVQKLQDVLHEALQDYEAGQHMEDPRRAGKMLMTLPLLRQTSTKAVQHFYNIKLEGK 420
DVEAVQKLQDVLHEALQDYEAGQHMEDPRRAGKMLMTLPLLRQTSTKAVQHFYNIKLEGK
Sbjct: 384 DVEAVQKLQDVLHEALQDYEAGQHMEDPRRAGKMLMTLPLLRQTSTKAVQHFYNIKLEGK 443
Query: 421 VPMHKLFLEMLEAKV 435
VPMHKLFLEMLEAKV
Sbjct: 444 VPMHKLFLEMLEAKV 458
>gi|197209821 estrogen-related receptor gamma isoform 2 [Homo
sapiens]
Length = 435
Score = 877 bits (2265), Expect = 0.0
Identities = 435/435 (100%), Positives = 435/435 (100%)
Query: 1 MSNKDRHIDSSCSSFIKTEPSSPASLTDSVNHHSPGGSSDASGSYSSTMNGHQNGLDSPP 60
MSNKDRHIDSSCSSFIKTEPSSPASLTDSVNHHSPGGSSDASGSYSSTMNGHQNGLDSPP
Sbjct: 1 MSNKDRHIDSSCSSFIKTEPSSPASLTDSVNHHSPGGSSDASGSYSSTMNGHQNGLDSPP 60
Query: 61 LYPSAPILGGSGPVRKLYDDCSSTIVEDPQTKCEYMLNSMPKRLCLVCGDIASGYHYGVA 120
LYPSAPILGGSGPVRKLYDDCSSTIVEDPQTKCEYMLNSMPKRLCLVCGDIASGYHYGVA
Sbjct: 61 LYPSAPILGGSGPVRKLYDDCSSTIVEDPQTKCEYMLNSMPKRLCLVCGDIASGYHYGVA 120
Query: 121 SCEACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQACRFMKCLKVGMLKEGVRLDRV 180
SCEACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQACRFMKCLKVGMLKEGVRLDRV
Sbjct: 121 SCEACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQACRFMKCLKVGMLKEGVRLDRV 180
Query: 181 RGGRQKYKRRIDAENSPYLNPQLVQPAKKPYNKIVSHLLVAEPEKIYAMPDPTVPDSDIK 240
RGGRQKYKRRIDAENSPYLNPQLVQPAKKPYNKIVSHLLVAEPEKIYAMPDPTVPDSDIK
Sbjct: 181 RGGRQKYKRRIDAENSPYLNPQLVQPAKKPYNKIVSHLLVAEPEKIYAMPDPTVPDSDIK 240
Query: 241 ALTTLCDLADRELVVIIGWAKHIPGFSTLSLADQMSLLQSAWMEILILGVVYRSLSFEDE 300
ALTTLCDLADRELVVIIGWAKHIPGFSTLSLADQMSLLQSAWMEILILGVVYRSLSFEDE
Sbjct: 241 ALTTLCDLADRELVVIIGWAKHIPGFSTLSLADQMSLLQSAWMEILILGVVYRSLSFEDE 300
Query: 301 LVYADDYIMDEDQSKLAGLLDLNNAILQLVKKYKSMKLEKEEFVTLKAIALANSDSMHIE 360
LVYADDYIMDEDQSKLAGLLDLNNAILQLVKKYKSMKLEKEEFVTLKAIALANSDSMHIE
Sbjct: 301 LVYADDYIMDEDQSKLAGLLDLNNAILQLVKKYKSMKLEKEEFVTLKAIALANSDSMHIE 360
Query: 361 DVEAVQKLQDVLHEALQDYEAGQHMEDPRRAGKMLMTLPLLRQTSTKAVQHFYNIKLEGK 420
DVEAVQKLQDVLHEALQDYEAGQHMEDPRRAGKMLMTLPLLRQTSTKAVQHFYNIKLEGK
Sbjct: 361 DVEAVQKLQDVLHEALQDYEAGQHMEDPRRAGKMLMTLPLLRQTSTKAVQHFYNIKLEGK 420
Query: 421 VPMHKLFLEMLEAKV 435
VPMHKLFLEMLEAKV
Sbjct: 421 VPMHKLFLEMLEAKV 435
>gi|238550159 estrogen-related receptor beta [Homo sapiens]
Length = 508
Score = 697 bits (1800), Expect = 0.0
Identities = 338/435 (77%), Positives = 388/435 (89%), Gaps = 2/435 (0%)
Query: 1 MSNKDRHIDSSCSSFIKTEPSSPASLTDSVNHHSPGGSSDASGSYSSTMNGHQNGLDSPP 60
MS+ DRH+ SSC SFIKTEPSSP+S D+++HHSP GSSDASG + + H NGLDSPP
Sbjct: 1 MSSDDRHLGSSCGSFIKTEPSSPSSGIDALSHHSPSGSSDASGGFGLALGTHANGLDSPP 60
Query: 61 LYPSAPILGGSGPVRKLYDDCSSTIVEDPQTKCEYMLNSMPKRLCLVCGDIASGYHYGVA 120
++ A + G P RK Y+DC+S I+ED KCEYMLN++PKRLCLVCGDIASGYHYGVA
Sbjct: 61 MFAGAGL--GGTPCRKSYEDCASGIMEDSAIKCEYMLNAIPKRLCLVCGDIASGYHYGVA 118
Query: 121 SCEACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQACRFMKCLKVGMLKEGVRLDRV 180
SCEACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQACRFMKCLKVGMLKEGVRLDRV
Sbjct: 119 SCEACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQACRFMKCLKVGMLKEGVRLDRV 178
Query: 181 RGGRQKYKRRIDAENSPYLNPQLVQPAKKPYNKIVSHLLVAEPEKIYAMPDPTVPDSDIK 240
RGGRQKYKRR+D+E+SPYL+ Q+ PAKKP KIVS+LLVAEP+K+YAMP P +P+ DIK
Sbjct: 179 RGGRQKYKRRLDSESSPYLSLQISPPAKKPLTKIVSYLLVAEPDKLYAMPPPGMPEGDIK 238
Query: 241 ALTTLCDLADRELVVIIGWAKHIPGFSTLSLADQMSLLQSAWMEILILGVVYRSLSFEDE 300
ALTTLCDLADRELVVIIGWAKHIPGFS+LSL DQMSLLQSAWMEILILG+VYRSL ++D+
Sbjct: 239 ALTTLCDLADRELVVIIGWAKHIPGFSSLSLGDQMSLLQSAWMEILILGIVYRSLPYDDK 298
Query: 301 LVYADDYIMDEDQSKLAGLLDLNNAILQLVKKYKSMKLEKEEFVTLKAIALANSDSMHIE 360
LVYA+DYIMDE+ S+LAGLL+L AILQLV++YK +K+EKEEFVTLKA+ALANSDSM+IE
Sbjct: 299 LVYAEDYIMDEEHSRLAGLLELYRAILQLVRRYKKLKVEKEEFVTLKALALANSDSMYIE 358
Query: 361 DVEAVQKLQDVLHEALQDYEAGQHMEDPRRAGKMLMTLPLLRQTSTKAVQHFYNIKLEGK 420
D+EAVQKLQD+LHEALQDYE Q E+P R GK+L+TLPLLRQT+ KAVQHFY++KL+GK
Sbjct: 359 DLEAVQKLQDLLHEALQDYELSQRHEEPWRTGKLLLTLPLLRQTAAKAVQHFYSVKLQGK 418
Query: 421 VPMHKLFLEMLEAKV 435
VPMHKLFLEMLEAKV
Sbjct: 419 VPMHKLFLEMLEAKV 433
>gi|18860920 estrogen-related receptor alpha [Homo sapiens]
Length = 423
Score = 476 bits (1226), Expect = e-134
Identities = 249/436 (57%), Positives = 310/436 (71%), Gaps = 44/436 (10%)
Query: 15 FIKTEPSSPASLTDSVNHHSPGGSSDASGSYSSTMNGHQNGLDSPPLYPSAPILGGSGPV 74
+IK EP+SP SP GSS+ P + G P
Sbjct: 12 YIKAEPASP---------DSPKGSSETETE------------------PPVALAPGPAPT 44
Query: 75 RKL----YDDCSSTIVEDPQTKCEYMLNSMPKRLCLVCGDIASGYHYGVASCEACKAFFK 130
R L ++ Q + +L+S+PKRLCLVCGD+ASGYHYGVASCEACKAFFK
Sbjct: 45 RCLPGHKEEEDGEGAGPGEQGGGKLVLSSLPKRLCLVCGDVASGYHYGVASCEACKAFFK 104
Query: 131 RTIQGNIEYSCPATNECEITKRRRKSCQACRFMKCLKVGMLKEGVRLDRVRGGRQKYKRR 190
RTIQG+IEYSCPA+NECEITKRRRK+CQACRF KCL+VGMLKEGVRLDRVRGGRQKYKRR
Sbjct: 105 RTIQGSIEYSCPASNECEITKRRRKACQACRFTKCLRVGMLKEGVRLDRVRGGRQKYKRR 164
Query: 191 IDAENSPYLNPQLVQP---------AKKPYNKIVSHLLVAEPEKIYAMPDPTVPDSDIKA 241
+ + P+ P P P N +VSHLLV EPEK+YAMPDP PD + A
Sbjct: 165 PEVDPLPFPGPFPAGPLAVAGGPRKTAAPVNALVSHLLVVEPEKLYAMPDPAGPDGHLPA 224
Query: 242 LTTLCDLADRELVVIIGWAKHIPGFSTLSLADQMSLLQSAWMEILILGVVYRSLSFEDEL 301
+ TLCDL DRE+VV I WAK IPGFS+LSL+DQMS+LQS WME+L+LGV RSL +DEL
Sbjct: 225 VATLCDLFDREIVVTISWAKSIPGFSSLSLSDQMSVLQSVWMEVLVLGVAQRSLPLQDEL 284
Query: 302 VYADDYIMDEDQSKLAGLLDLNNAILQLVKKYKSMKLEKEEFVTLKAIALANSDSMHIED 361
+A+D ++DE+ ++ AGL +L A+LQLV++ ++++LE+EE+V LKA+ALANSDS+HIED
Sbjct: 285 AFAEDLVLDEEGARAAGLGELGAALLQLVRRLQALRLEREEYVLLKALALANSDSVHIED 344
Query: 362 VEAVQKLQDVLHEALQDYEAGQ----HMEDPRRAGKMLMTLPLLRQTSTKAVQHFYNIKL 417
EAV++L++ LHEAL +YEAG+ + RRAG++L+TLPLLRQT+ K + HFY +KL
Sbjct: 345 AEAVEQLREALHEALLEYEAGRAGPGGGAERRRAGRLLLTLPLLRQTAGKVLAHFYGVKL 404
Query: 418 EGKVPMHKLFLEMLEA 433
EGKVPMHKLFLEMLEA
Sbjct: 405 EGKVPMHKLFLEMLEA 420
>gi|170295804 estrogen receptor alpha isoform 4 [Homo sapiens]
Length = 595
Score = 263 bits (673), Expect = 2e-70
Identities = 151/372 (40%), Positives = 229/372 (61%), Gaps = 35/372 (9%)
Query: 96 MLNSMPKRLCLVCGDIASGYHYGVASCEACKAFFKRTIQGNIEYSCPATNECEITKRRRK 155
M ++ R C VC D ASGYHYGV SCE CKAFFKR+IQG+ +Y CPATN+C I K RRK
Sbjct: 176 MESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRK 235
Query: 156 SCQACRFMKCLKVGMLKEGVRLDRVRGGRQ-KYKR-RIDAEN-------------SPYLN 200
SCQACR KC +VGM+K G+R DR RGGR K+KR R D E + + +
Sbjct: 236 SCQACRLRKCYEVGMMKGGIRKDR-RGGRMLKHKRQRDDGEGRGEVGSAGDMRAANLWPS 294
Query: 201 PQLVQPAKK-------PYNKIVSHLLVAEPEKIYAMPDPTVPDSDIKALTTLCDLADREL 253
P +++ +KK +++VS LL AEP +Y+ DPT P S+ + L +LADREL
Sbjct: 295 PLMIKRSKKNSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADREL 354
Query: 254 VVIIGWAKHIPGFSTLSLADQMSLLQSAWMEILILGVVYRSLSFEDELVYADDYIMDEDQ 313
V +I WAK +PGF L+L DQ+ LL+ AW+EIL++G+V+RS+ +L++A + ++D +Q
Sbjct: 355 VHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQ 414
Query: 314 SK-LAGLLDLNNAILQLVKKYKSMKLEKEEFVTLKAIALAN--------SDSMHIEDVEA 364
K + G++++ + +L +++ M L+ EEFV LK+I L N S +E+ +
Sbjct: 415 GKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDH 474
Query: 365 VQKLQDVLHEALQDYEAGQHM---EDPRRAGKMLMTLPLLRQTSTKAVQHFYNIKLEGKV 421
+ ++ D + + L A + + +R ++L+ L +R S K ++H Y++K + V
Sbjct: 475 IHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVV 534
Query: 422 PMHKLFLEMLEA 433
P++ L LEML+A
Sbjct: 535 PLYDLLLEMLDA 546
>gi|170295802 estrogen receptor alpha isoform 3 [Homo sapiens]
Length = 595
Score = 263 bits (673), Expect = 2e-70
Identities = 151/372 (40%), Positives = 229/372 (61%), Gaps = 35/372 (9%)
Query: 96 MLNSMPKRLCLVCGDIASGYHYGVASCEACKAFFKRTIQGNIEYSCPATNECEITKRRRK 155
M ++ R C VC D ASGYHYGV SCE CKAFFKR+IQG+ +Y CPATN+C I K RRK
Sbjct: 176 MESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRK 235
Query: 156 SCQACRFMKCLKVGMLKEGVRLDRVRGGRQ-KYKR-RIDAEN-------------SPYLN 200
SCQACR KC +VGM+K G+R DR RGGR K+KR R D E + + +
Sbjct: 236 SCQACRLRKCYEVGMMKGGIRKDR-RGGRMLKHKRQRDDGEGRGEVGSAGDMRAANLWPS 294
Query: 201 PQLVQPAKK-------PYNKIVSHLLVAEPEKIYAMPDPTVPDSDIKALTTLCDLADREL 253
P +++ +KK +++VS LL AEP +Y+ DPT P S+ + L +LADREL
Sbjct: 295 PLMIKRSKKNSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADREL 354
Query: 254 VVIIGWAKHIPGFSTLSLADQMSLLQSAWMEILILGVVYRSLSFEDELVYADDYIMDEDQ 313
V +I WAK +PGF L+L DQ+ LL+ AW+EIL++G+V+RS+ +L++A + ++D +Q
Sbjct: 355 VHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQ 414
Query: 314 SK-LAGLLDLNNAILQLVKKYKSMKLEKEEFVTLKAIALAN--------SDSMHIEDVEA 364
K + G++++ + +L +++ M L+ EEFV LK+I L N S +E+ +
Sbjct: 415 GKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDH 474
Query: 365 VQKLQDVLHEALQDYEAGQHM---EDPRRAGKMLMTLPLLRQTSTKAVQHFYNIKLEGKV 421
+ ++ D + + L A + + +R ++L+ L +R S K ++H Y++K + V
Sbjct: 475 IHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVV 534
Query: 422 PMHKLFLEMLEA 433
P++ L LEML+A
Sbjct: 535 PLYDLLLEMLDA 546
>gi|170295800 estrogen receptor alpha isoform 2 [Homo sapiens]
Length = 595
Score = 263 bits (673), Expect = 2e-70
Identities = 151/372 (40%), Positives = 229/372 (61%), Gaps = 35/372 (9%)
Query: 96 MLNSMPKRLCLVCGDIASGYHYGVASCEACKAFFKRTIQGNIEYSCPATNECEITKRRRK 155
M ++ R C VC D ASGYHYGV SCE CKAFFKR+IQG+ +Y CPATN+C I K RRK
Sbjct: 176 MESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRK 235
Query: 156 SCQACRFMKCLKVGMLKEGVRLDRVRGGRQ-KYKR-RIDAEN-------------SPYLN 200
SCQACR KC +VGM+K G+R DR RGGR K+KR R D E + + +
Sbjct: 236 SCQACRLRKCYEVGMMKGGIRKDR-RGGRMLKHKRQRDDGEGRGEVGSAGDMRAANLWPS 294
Query: 201 PQLVQPAKK-------PYNKIVSHLLVAEPEKIYAMPDPTVPDSDIKALTTLCDLADREL 253
P +++ +KK +++VS LL AEP +Y+ DPT P S+ + L +LADREL
Sbjct: 295 PLMIKRSKKNSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADREL 354
Query: 254 VVIIGWAKHIPGFSTLSLADQMSLLQSAWMEILILGVVYRSLSFEDELVYADDYIMDEDQ 313
V +I WAK +PGF L+L DQ+ LL+ AW+EIL++G+V+RS+ +L++A + ++D +Q
Sbjct: 355 VHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQ 414
Query: 314 SK-LAGLLDLNNAILQLVKKYKSMKLEKEEFVTLKAIALAN--------SDSMHIEDVEA 364
K + G++++ + +L +++ M L+ EEFV LK+I L N S +E+ +
Sbjct: 415 GKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDH 474
Query: 365 VQKLQDVLHEALQDYEAGQHM---EDPRRAGKMLMTLPLLRQTSTKAVQHFYNIKLEGKV 421
+ ++ D + + L A + + +R ++L+ L +R S K ++H Y++K + V
Sbjct: 475 IHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVV 534
Query: 422 PMHKLFLEMLEA 433
P++ L LEML+A
Sbjct: 535 PLYDLLLEMLDA 546
>gi|62821794 estrogen receptor alpha isoform 1 [Homo sapiens]
Length = 595
Score = 263 bits (673), Expect = 2e-70
Identities = 151/372 (40%), Positives = 229/372 (61%), Gaps = 35/372 (9%)
Query: 96 MLNSMPKRLCLVCGDIASGYHYGVASCEACKAFFKRTIQGNIEYSCPATNECEITKRRRK 155
M ++ R C VC D ASGYHYGV SCE CKAFFKR+IQG+ +Y CPATN+C I K RRK
Sbjct: 176 MESAKETRYCAVCNDYASGYHYGVWSCEGCKAFFKRSIQGHNDYMCPATNQCTIDKNRRK 235
Query: 156 SCQACRFMKCLKVGMLKEGVRLDRVRGGRQ-KYKR-RIDAEN-------------SPYLN 200
SCQACR KC +VGM+K G+R DR RGGR K+KR R D E + + +
Sbjct: 236 SCQACRLRKCYEVGMMKGGIRKDR-RGGRMLKHKRQRDDGEGRGEVGSAGDMRAANLWPS 294
Query: 201 PQLVQPAKK-------PYNKIVSHLLVAEPEKIYAMPDPTVPDSDIKALTTLCDLADREL 253
P +++ +KK +++VS LL AEP +Y+ DPT P S+ + L +LADREL
Sbjct: 295 PLMIKRSKKNSLALSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADREL 354
Query: 254 VVIIGWAKHIPGFSTLSLADQMSLLQSAWMEILILGVVYRSLSFEDELVYADDYIMDEDQ 313
V +I WAK +PGF L+L DQ+ LL+ AW+EIL++G+V+RS+ +L++A + ++D +Q
Sbjct: 355 VHMINWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPNLLLDRNQ 414
Query: 314 SK-LAGLLDLNNAILQLVKKYKSMKLEKEEFVTLKAIALAN--------SDSMHIEDVEA 364
K + G++++ + +L +++ M L+ EEFV LK+I L N S +E+ +
Sbjct: 415 GKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSGVYTFLSSTLKSLEEKDH 474
Query: 365 VQKLQDVLHEALQDYEAGQHM---EDPRRAGKMLMTLPLLRQTSTKAVQHFYNIKLEGKV 421
+ ++ D + + L A + + +R ++L+ L +R S K ++H Y++K + V
Sbjct: 475 IHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSHIRHMSNKGMEHLYSMKCKNVV 534
Query: 422 PMHKLFLEMLEA 433
P++ L LEML+A
Sbjct: 535 PLYDLLLEMLDA 546
>gi|10835013 estrogen receptor beta isoform 1 [Homo sapiens]
Length = 530
Score = 242 bits (617), Expect = 6e-64
Identities = 139/355 (39%), Positives = 215/355 (60%), Gaps = 28/355 (7%)
Query: 105 CLVCGDIASGYHYGVASCEACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQACRFMK 164
C VC D ASGYHYGV SCE CKAFFKR+IQG+ +Y CPATN+C I K RRKSCQACR K
Sbjct: 149 CAVCSDYASGYHYGVWSCEGCKAFFKRSIQGHNDYICPATNQCTIDKNRRKSCQACRLRK 208
Query: 165 CLKVGMLKEGVRLDRVRGGRQKYKRRIDAE------------NSPYLNPQLVQPAKKPYN 212
C +VGM+K G R +R + +R D + ++P + +L+ A P
Sbjct: 209 CYEVGMVKCGSRRERCGYRLVRRQRSADEQLHCAGKAKRSGGHAPRVR-ELLLDALSP-E 266
Query: 213 KIVSHLLVAEPEKIYAMPDPTVPDSDIKALTTLCDLADRELVVIIGWAKHIPGFSTLSLA 272
++V LL AEP + + P+ P ++ + +L LAD+ELV +I WAK IPGF LSL
Sbjct: 267 QLVLTLLEAEPPHV-LISRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLF 325
Query: 273 DQMSLLQSAWMEILILGVVYRSLSFEDELVYADDYIMDEDQSK-LAGLLDLNNAILQLVK 331
DQ+ LL+S WME+L++G+++RS+ +L++A D ++D D+ K + G+L++ + +L
Sbjct: 326 DQVRLLESCWMEVLMMGLMWRSIDHPGKLIFAPDLVLDRDEGKCVEGILEIFDMLLATTS 385
Query: 332 KYKSMKLEKEEFVTLKAIALANSDSMHI----EDVEAVQKLQDVLHEALQD------YEA 381
+++ +KL+ +E++ +KA+ L NS + +D ++ +KL +L+ A+ D ++
Sbjct: 386 RFRELKLQHKEYLCVKAMILLNSSMYPLVTATQDADSSRKLAHLLN-AVTDALVWVIAKS 444
Query: 382 G-QHMEDPRRAGKMLMTLPLLRQTSTKAVQHFYNIKLEGKVPMHKLFLEMLEAKV 435
G + R +LM L +R S K ++H N+K + VP++ L LEML A V
Sbjct: 445 GISSQQQSMRLANLLMLLSHVRHASNKGMEHLLNMKCKNVVPVYDLLLEMLNAHV 499
>gi|4506755 retinoid X receptor, alpha [Homo sapiens]
Length = 462
Score = 219 bits (559), Expect = 3e-57
Identities = 145/447 (32%), Positives = 229/447 (51%), Gaps = 40/447 (8%)
Query: 18 TEPSSPASLTDSVNHHSPG---GSSDASGSYSSTMNGHQNGLDSP------PL------Y 62
T P+ S+ H S G GS S ST++ NG+ P P+
Sbjct: 20 TSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPINGMGPPFSVISSPMGPHSMSV 79
Query: 63 PSAPILG---GSGPVRKLYDDCSSTIVEDPQTKCEYMLN----------SMPKRLCLVCG 109
P+ P LG GS + + SS+ P +L S K +C +CG
Sbjct: 80 PTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVPAHPSGNMASFTKHICAICG 139
Query: 110 DIASGYHYGVASCEACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQACRFMKCLKVG 169
D +SG HYGV SCE CK FFKRT++ ++ Y+C +C I KR+R CQ CR+ KCL +G
Sbjct: 140 DRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLIDKRQRNRCQYCRYQKCLAMG 199
Query: 170 MLKEGVRLDRVRGGRQKYKRRIDAENSPYLNPQLVQPAKKPYNKIVSHLLVAEPE-KIYA 228
M +E V+ +R RG K + + E++ N + P +I+ L EP+ + Y
Sbjct: 200 MKREAVQEERQRG---KDRNENEVESTSSANEDM------PVERILEAELAVEPKTETYV 250
Query: 229 MPDPTV-PDSDIKALTTLCDLADRELVVIIGWAKHIPGFSTLSLADQMSLLQSAWMEILI 287
+ + P S +T +C AD++L ++ WAK IP FS L L DQ+ LL++ W E+LI
Sbjct: 251 EANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVILLRAGWNELLI 310
Query: 288 LGVVYRSLSFEDELVYADDYIMDEDQSKLAGLLDLNNAIL-QLVKKYKSMKLEKEEFVTL 346
+RS++ +D ++ A + + + AG+ + + +L +LV K + M+++K E L
Sbjct: 311 ASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDMQMDKTELGCL 370
Query: 347 KAIALANSDSMHIEDVEAVQKLQDVLHEALQDYEAGQHMEDPRRAGKMLMTLPLLRQTST 406
+AI L N DS + + V+ L++ ++ +L+ Y ++ E P R K+L+ LP LR
Sbjct: 371 RAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLLRLPALRSIGL 430
Query: 407 KAVQHFYNIKLEGKVPMHKLFLEMLEA 433
K ++H + KL G P+ +EMLEA
Sbjct: 431 KCLEHLFFFKLIGDTPIDTFLMEMLEA 457
>gi|5902068 retinoid X receptor, gamma isoform a [Homo sapiens]
Length = 463
Score = 218 bits (556), Expect = 7e-57
Identities = 119/335 (35%), Positives = 189/335 (56%), Gaps = 11/335 (3%)
Query: 99 SMPKRLCLVCGDIASGYHYGVASCEACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQ 158
S+ K +C +CGD +SG HYGV SCE CK FFKRTI+ ++ Y+C +C I KR+R CQ
Sbjct: 133 SLVKHICAICGDRSSGKHYGVYSCEGCKGFFKRTIRKDLIYTCRDNKDCLIDKRQRNRCQ 192
Query: 159 ACRFMKCLKVGMLKEGVRLDRVRGGRQKYKRRIDAENSPYLNPQLVQPAKKPYNKIVSHL 218
CR+ KCL +GM +E V+ +R R R++ + + S + P +I+
Sbjct: 193 YCRYQKCLVMGMKREAVQEERQR-SRERAESEAECATSGH--------EDMPVERILEAE 243
Query: 219 LVAEPEKIYAMPDPTVPDSDIKALTTLCDLADRELVVIIGWAKHIPGFSTLSLADQMSLL 278
L EP K + D + +S +T +C AD++L ++ WAK IP FS L+L DQ+ LL
Sbjct: 244 LAVEP-KTESYGDMNMENSTNDPVTNICHAADKQLFTLVEWAKRIPHFSDLTLEDQVILL 302
Query: 279 QSAWMEILILGVVYRSLSFEDELVYADDYIMDEDQSKLAGLLDLNNAIL-QLVKKYKSMK 337
++ W E+LI +RS+S +D ++ A + + AG+ + + +L +LV K K M+
Sbjct: 303 RAGWNELLIASFSHRSVSVQDGILLATGLHVHRSSAHSAGVGSIFDRVLTELVSKMKDMQ 362
Query: 338 LEKEEFVTLKAIALANSDSMHIEDVEAVQKLQDVLHEALQDYEAGQHMEDPRRAGKMLMT 397
++K E L+AI L N D+ + + V+ L++ ++ L+ Y ++ E P R K+L+
Sbjct: 363 MDKSELGCLRAIVLFNPDAKGLSNPSEVETLREKVYATLEAYTKQKYPEQPGRFAKLLLR 422
Query: 398 LPLLRQTSTKAVQHFYNIKLEGKVPMHKLFLEMLE 432
LP LR K ++H + KL G P+ +EMLE
Sbjct: 423 LPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLE 457
>gi|94538328 estrogen receptor beta isoform 2 [Homo sapiens]
Length = 495
Score = 217 bits (552), Expect = 2e-56
Identities = 117/286 (40%), Positives = 181/286 (63%), Gaps = 20/286 (6%)
Query: 105 CLVCGDIASGYHYGVASCEACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQACRFMK 164
C VC D ASGYHYGV SCE CKAFFKR+IQG+ +Y CPATN+C I K RRKSCQACR K
Sbjct: 149 CAVCSDYASGYHYGVWSCEGCKAFFKRSIQGHNDYICPATNQCTIDKNRRKSCQACRLRK 208
Query: 165 CLKVGMLKEGVRLDRVRGGRQKYKRRIDAE------------NSPYLNPQLVQPAKKPYN 212
C +VGM+K G R +R + +R D + ++P + +L+ A P
Sbjct: 209 CYEVGMVKCGSRRERCGYRLVRRQRSADEQLHCAGKAKRSGGHAPRVR-ELLLDALSP-E 266
Query: 213 KIVSHLLVAEPEKIYAMPDPTVPDSDIKALTTLCDLADRELVVIIGWAKHIPGFSTLSLA 272
++V LL AEP + + P+ P ++ + +L LAD+ELV +I WAK IPGF LSL
Sbjct: 267 QLVLTLLEAEPPHV-LISRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLF 325
Query: 273 DQMSLLQSAWMEILILGVVYRSLSFEDELVYADDYIMDEDQSK-LAGLLDLNNAILQLVK 331
DQ+ LL+S WME+L++G+++RS+ +L++A D ++D D+ K + G+L++ + +L
Sbjct: 326 DQVRLLESCWMEVLMMGLMWRSIDHPGKLIFAPDLVLDRDEGKCVEGILEIFDMLLATTS 385
Query: 332 KYKSMKLEKEEFVTLKAIALANSDSMHI----EDVEAVQKLQDVLH 373
+++ +KL+ +E++ +KA+ L NS + +D ++ +KL +L+
Sbjct: 386 RFRELKLQHKEYLCVKAMILLNSSMYPLVTATQDADSSRKLAHLLN 431
>gi|94538325 estrogen receptor beta isoform 2 [Homo sapiens]
Length = 495
Score = 217 bits (552), Expect = 2e-56
Identities = 117/286 (40%), Positives = 181/286 (63%), Gaps = 20/286 (6%)
Query: 105 CLVCGDIASGYHYGVASCEACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQACRFMK 164
C VC D ASGYHYGV SCE CKAFFKR+IQG+ +Y CPATN+C I K RRKSCQACR K
Sbjct: 149 CAVCSDYASGYHYGVWSCEGCKAFFKRSIQGHNDYICPATNQCTIDKNRRKSCQACRLRK 208
Query: 165 CLKVGMLKEGVRLDRVRGGRQKYKRRIDAE------------NSPYLNPQLVQPAKKPYN 212
C +VGM+K G R +R + +R D + ++P + +L+ A P
Sbjct: 209 CYEVGMVKCGSRRERCGYRLVRRQRSADEQLHCAGKAKRSGGHAPRVR-ELLLDALSP-E 266
Query: 213 KIVSHLLVAEPEKIYAMPDPTVPDSDIKALTTLCDLADRELVVIIGWAKHIPGFSTLSLA 272
++V LL AEP + + P+ P ++ + +L LAD+ELV +I WAK IPGF LSL
Sbjct: 267 QLVLTLLEAEPPHV-LISRPSAPFTEASMMMSLTKLADKELVHMISWAKKIPGFVELSLF 325
Query: 273 DQMSLLQSAWMEILILGVVYRSLSFEDELVYADDYIMDEDQSK-LAGLLDLNNAILQLVK 331
DQ+ LL+S WME+L++G+++RS+ +L++A D ++D D+ K + G+L++ + +L
Sbjct: 326 DQVRLLESCWMEVLMMGLMWRSIDHPGKLIFAPDLVLDRDEGKCVEGILEIFDMLLATTS 385
Query: 332 KYKSMKLEKEEFVTLKAIALANSDSMHI----EDVEAVQKLQDVLH 373
+++ +KL+ +E++ +KA+ L NS + +D ++ +KL +L+
Sbjct: 386 RFRELKLQHKEYLCVKAMILLNSSMYPLVTATQDADSSRKLAHLLN 431
>gi|11415052 retinoid X receptor, beta [Homo sapiens]
Length = 533
Score = 209 bits (533), Expect = 3e-54
Identities = 118/337 (35%), Positives = 185/337 (54%), Gaps = 15/337 (4%)
Query: 102 KRLCLVCGDIASGYHYGVASCEACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQACR 161
KRLC +CGD +SG HYGV SCE CK FFKRTI+ ++ YSC +C + KR+R CQ CR
Sbjct: 202 KRLCAICGDRSSGKHYGVYSCEGCKGFFKRTIRKDLTYSCRDNKDCTVDKRQRNRCQYCR 261
Query: 162 FMKCLKVGMLKEGVRLDRVRGGRQKYKRRIDAENSPYLNPQLVQPAKKPYNKIVSHLLVA 221
+ KCL GM +E V+ +R RG + D E + P + P ++I+ L
Sbjct: 262 YQKCLATGMKREAVQEERQRG----KDKDGDGEGAG------GAPEEMPVDRILEAELAV 311
Query: 222 EPEKIYAMPDP----TVPDSDIKALTTLCDLADRELVVIIGWAKHIPGFSTLSLADQMSL 277
E + + P S +T +C AD++L ++ WAK IP FS+L L DQ+ L
Sbjct: 312 EQKSDQGVEGPGGTGGSGSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSSLPLDDQVIL 371
Query: 278 LQSAWMEILILGVVYRSLSFEDELVYADDYIMDEDQSKLAGLLDLNNAIL-QLVKKYKSM 336
L++ W E+LI +RS+ D ++ A + + + AG+ + + +L +LV K + M
Sbjct: 372 LRAGWNELLIASFSHRSIDVRDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDM 431
Query: 337 KLEKEEFVTLKAIALANSDSMHIEDVEAVQKLQDVLHEALQDYEAGQHMEDPRRAGKMLM 396
+++K E L+AI L N D+ + + V+ L++ ++ +L+ Y ++ E R K+L+
Sbjct: 432 RMDKTELGCLRAIILFNPDAKGLSNPSEVEVLREKVYASLETYCKQKYPEQQGRFAKLLL 491
Query: 397 TLPLLRQTSTKAVQHFYNIKLEGKVPMHKLFLEMLEA 433
LP LR K ++H + KL G P+ +EMLEA
Sbjct: 492 RLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEA 528
>gi|4506423 retinoic acid receptor, gamma isoform 1 [Homo sapiens]
Length = 454
Score = 199 bits (507), Expect = 3e-51
Identities = 134/389 (34%), Positives = 194/389 (49%), Gaps = 21/389 (5%)
Query: 58 SPPLYPSAPILGGSGPVRKLYDDCSSTIVEDPQTKCEYMLNSMPK--------RLCLVCG 109
SPP +P G G L + +S VE T E M+ S P + C VC
Sbjct: 36 SPPFEMLSPSFRGLGQP-DLPKEMASLSVETQSTSSEEMVPSSPSPPPPPRVYKPCFVCN 94
Query: 110 DIASGYHYGVASCEACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQACRFMKCLKVG 169
D +SGYHYGV+SCE CK FF+R+IQ N+ Y+C C I K R CQ CR KC +VG
Sbjct: 95 DKSSGYHYGVSSCEGCKGFFRRSIQKNMVYTCHRDKNCIINKVTRNRCQYCRLQKCFEVG 154
Query: 170 MLKEGVRLDRVRGGRQKYKRRIDAENSP---YLNPQL---VQPAKKPYNKIVSHLLVAEP 223
M KE VR DR K K+ + E SP L+PQL + K + + L
Sbjct: 155 MSKEAVRNDR-----NKKKKEVKEEGSPDSYELSPQLEELITKVSKAHQETFPSLCQLGK 209
Query: 224 EKIYAMPDPTVPDSDIKALTTLCDLADRELVVIIGWAKHIPGFSTLSLADQMSLLQSAWM 283
+ D V D+ +LA + ++ I+ +AK +PGF+ LS+ADQ++LL++A +
Sbjct: 210 YTTNSSADHRV-QLDLGLWDKFSELATKCIIKIVEFAKRLPGFTGLSIADQITLLKAACL 268
Query: 284 EILILGVVYRSLSFEDELVYADDYIMDEDQSKLAGLLDLNNAILQLVKKYKSMKLEKEEF 343
+IL+L + R +D + ++D ++ Q AG L + + + ++++ E
Sbjct: 269 DILMLRICTRYTPEQDTMTFSDGLTLNRTQMHNAGFGPLTDLVFAFAGQLLPLEMDDTET 328
Query: 344 VTLKAIALANSDSMHIEDVEAVQKLQDVLHEALQDYEAGQHMEDPRRAGKMLMTLPLLRQ 403
L AI L D M +E+ E V KLQ+ L EAL+ Y + P +MLM + LR
Sbjct: 329 GLLSAICLICGDRMDLEEPEKVDKLQEPLLEALRLYARRRRPSQPYMFPRMLMKITDLRG 388
Query: 404 TSTKAVQHFYNIKLEGKVPMHKLFLEMLE 432
STK + +K+E PM L EMLE
Sbjct: 389 ISTKGAERAITLKMEIPGPMPPLIREMLE 417
>gi|112181200 retinoic acid receptor, gamma isoform 2 [Homo sapiens]
Length = 443
Score = 194 bits (494), Expect = 1e-49
Identities = 126/361 (34%), Positives = 183/361 (50%), Gaps = 20/361 (5%)
Query: 86 VEDPQTKCEYMLNSMPK--------RLCLVCGDIASGYHYGVASCEACKAFFKRTIQGNI 137
VE T E M+ S P + C VC D +SGYHYGV+SCE CK FF+R+IQ N+
Sbjct: 52 VETQSTSSEEMVPSSPSPPPPPRVYKPCFVCNDKSSGYHYGVSSCEGCKGFFRRSIQKNM 111
Query: 138 EYSCPATNECEITKRRRKSCQACRFMKCLKVGMLKEGVRLDRVRGGRQKYKRRIDAENSP 197
Y+C C I K R CQ CR KC +VGM KE VR DR K K+ + E SP
Sbjct: 112 VYTCHRDKNCIINKVTRNRCQYCRLQKCFEVGMSKEAVRNDR-----NKKKKEVKEEGSP 166
Query: 198 ---YLNPQL---VQPAKKPYNKIVSHLLVAEPEKIYAMPDPTVPDSDIKALTTLCDLADR 251
L+PQL + K + + L + D V D+ +LA +
Sbjct: 167 DSYELSPQLEELITKVSKAHQETFPSLCQLGKYTTNSSADHRV-QLDLGLWDKFSELATK 225
Query: 252 ELVVIIGWAKHIPGFSTLSLADQMSLLQSAWMEILILGVVYRSLSFEDELVYADDYIMDE 311
++ I+ +AK +PGF+ LS+ADQ++LL++A ++IL+L + R +D + ++D ++
Sbjct: 226 CIIKIVEFAKRLPGFTGLSIADQITLLKAACLDILMLRICTRYTPEQDTMTFSDGLTLNR 285
Query: 312 DQSKLAGLLDLNNAILQLVKKYKSMKLEKEEFVTLKAIALANSDSMHIEDVEAVQKLQDV 371
Q AG L + + + ++++ E L AI L D M +E+ E V KLQ+
Sbjct: 286 TQMHNAGFGPLTDLVFAFAGQLLPLEMDDTETGLLSAICLICGDRMDLEEPEKVDKLQEP 345
Query: 372 LHEALQDYEAGQHMEDPRRAGKMLMTLPLLRQTSTKAVQHFYNIKLEGKVPMHKLFLEML 431
L EAL+ Y + P +MLM + LR STK + +K+E PM L EML
Sbjct: 346 LLEALRLYARRRRPSQPYMFPRMLMKITDLRGISTKGAERAITLKMEIPGPMPPLIREML 405
Query: 432 E 432
E
Sbjct: 406 E 406
>gi|14149746 nuclear receptor subfamily 2, group F, member 2 isoform
a [Homo sapiens]
Length = 414
Score = 191 bits (486), Expect = 9e-49
Identities = 110/329 (33%), Positives = 169/329 (51%), Gaps = 9/329 (2%)
Query: 105 CLVCGDIASGYHYGVASCEACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQACRFMK 164
C+VCGD +SG HYG +CE CK+FFKR+++ N+ Y+C A C I + R CQ CR K
Sbjct: 79 CVVCGDKSSGKHYGQFTCEGCKSFFKRSVRRNLSYTCRANRNCPIDQHHRNQCQYCRLKK 138
Query: 165 CLKVGMLKEGVRLDRVRGGRQKYKRRIDAENSPYLNPQLVQPAKKPYNKIVSHLLVAEPE 224
CLKVGM +E V+ R+ Q + N LN + +S LL AEP
Sbjct: 139 CLKVGMRREAVQRGRM-PPTQPTHGQFALTNGDPLN------CHSYLSGYISLLLRAEPY 191
Query: 225 KIYAMPDPTVPDSDIKALTTLCDLADRELVVIIGWAKHIPGFSTLSLADQMSLLQSAWME 284
+ ++I + +C+LA R L + WA++IP F L + DQ++LL+ W E
Sbjct: 192 PTSRFGSQCMQPNNIMGIENICELAARMLFSAVEWARNIPFFPDLQITDQVALLRLTWSE 251
Query: 285 ILILGVVYRS--LSFEDELVYADDYIMDEDQSKLAGLLDLNNAILQLVKKYKSMKLEKEE 342
+ +L S L L A + ++ +D + V+K K++ ++ E
Sbjct: 252 LFVLNAAQCSMPLHVAPLLAAAGLHASPMSADRVVAFMDHIRIFQEQVEKLKALHVDSAE 311
Query: 343 FVTLKAIALANSDSMHIEDVEAVQKLQDVLHEALQDYEAGQHMEDPRRAGKMLMTLPLLR 402
+ LKAI L SD+ + DV V+ LQ+ AL++Y Q+ P R GK+L+ LP LR
Sbjct: 312 YSCLKAIVLFTSDACGLSDVAHVESLQEKSQCALEEYVRSQYPNQPTRFGKLLLRLPSLR 371
Query: 403 QTSTKAVQHFYNIKLEGKVPMHKLFLEML 431
S+ ++ + ++L GK P+ L +ML
Sbjct: 372 TVSSSVIEQLFFVRLVGKTPIETLIRDML 400
>gi|5032173 nuclear receptor subfamily 2, group F, member 1 [Homo
sapiens]
Length = 423
Score = 189 bits (480), Expect = 4e-48
Identities = 109/329 (33%), Positives = 168/329 (51%), Gaps = 9/329 (2%)
Query: 105 CLVCGDIASGYHYGVASCEACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQACRFMK 164
C+VCGD +SG HYG +CE CK+FFKR+++ N+ Y+C A C I + R CQ CR K
Sbjct: 86 CVVCGDKSSGKHYGQFTCEGCKSFFKRSVRRNLTYTCRANRNCPIDQHHRNQCQYCRLKK 145
Query: 165 CLKVGMLKEGVRLDRVRGGRQKYKRRIDAENSPYLNPQLVQPAKKPYNKIVSHLLVAEPE 224
CLKVGM +E V+ R+ Q + N LN + +S LL AEP
Sbjct: 146 CLKVGMRREAVQRGRM-PPTQPNPGQYALTNGDPLNGHCY------LSGYISLLLRAEPY 198
Query: 225 KIYAMPDPTVPDSDIKALTTLCDLADRELVVIIGWAKHIPGFSTLSLADQMSLLQSAWME 284
+ ++I + +C+LA R L + WA++IP F L + DQ+SLL+ W E
Sbjct: 199 PTSRYGSQCMQPNNIMGIENICELAARLLFSAVEWARNIPFFPDLQITDQVSLLRLTWSE 258
Query: 285 ILILGVVYRS--LSFEDELVYADDYIMDEDQSKLAGLLDLNNAILQLVKKYKSMKLEKEE 342
+ +L S L L A + ++ +D + V+K K++ ++ E
Sbjct: 259 LFVLNAAQCSMPLHVAPLLAAAGLHASPMSADRVVAFMDHIRIFQEQVEKLKALHVDSAE 318
Query: 343 FVTLKAIALANSDSMHIEDVEAVQKLQDVLHEALQDYEAGQHMEDPRRAGKMLMTLPLLR 402
+ LKAI L SD+ + D ++ LQ+ AL++Y Q+ P R GK+L+ LP LR
Sbjct: 319 YSCLKAIVLFTSDACGLSDAAHIESLQEKSQCALEEYVRSQYPNQPSRFGKLLLRLPSLR 378
Query: 403 QTSTKAVQHFYNIKLEGKVPMHKLFLEML 431
S+ ++ + ++L GK P+ L +ML
Sbjct: 379 TVSSSVIEQLFFVRLVGKTPIETLIRDML 407
>gi|223718064 retinoic acid receptor, alpha isoform 1 [Homo sapiens]
Length = 462
Score = 188 bits (477), Expect = 9e-48
Identities = 129/414 (31%), Positives = 197/414 (47%), Gaps = 26/414 (6%)
Query: 42 SGSYSSTMNGHQNGLDSPPL-YPSAPILGGSGPVRKL-----------YDDCSSTIVEDP 89
S S + GH NG PP + P+LGG P L Y S +E
Sbjct: 5 SSSCPTPGGGHLNGYPVPPYAFFFPPMLGGLSPPGALTTLQHQLPVSGYSTPSPATIETQ 64
Query: 90 QTKCEYMLNSMPK--------RLCLVCGDIASGYHYGVASCEACKAFFKRTIQGNIEYSC 141
+ E ++ S P + C VC D +SGYHYGV++CE CK FF+R+IQ N+ Y+C
Sbjct: 65 SSSSEEIVPSPPSPPPLPRIYKPCFVCQDKSSGYHYGVSACEGCKGFFRRSIQKNMVYTC 124
Query: 142 PATNECEITKRRRKSCQACRFMKCLKVGMLKEGVRLDRVRGGRQKYKRRIDAENSPYLNP 201
C I K R CQ CR KC +VGM KE VR DR + ++K + + S L P
Sbjct: 125 HRDKNCIINKVTRNRCQYCRLQKCFEVGMSKESVRNDRNK--KKKEVPKPECSESYTLTP 182
Query: 202 ---QLVQPAKKPYNKIVSHLLVAEPEKIYAMPDPTVPDSDIKALTTLCDLADRELVVIIG 258
+L++ +K + + L + V DI +L+ + ++ +
Sbjct: 183 EVGELIEKVRKAHQETFPALCQLGKYTTNNSSEQRV-SLDIDLWDKFSELSTKCIIKTVE 241
Query: 259 WAKHIPGFSTLSLADQMSLLQSAWMEILILGVVYRSLSFEDELVYADDYIMDEDQSKLAG 318
+AK +PGF+TL++ADQ++LL++A ++ILIL + R +D + ++D ++ Q AG
Sbjct: 242 FAKQLPGFTTLTIADQITLLKAACLDILILRICTRYTPEQDTMTFSDGLTLNRTQMHNAG 301
Query: 319 LLDLNNAILQLVKKYKSMKLEKEEFVTLKAIALANSDSMHIEDVEAVQKLQDVLHEALQD 378
L + + + ++++ E L AI L D +E + V LQ+ L EAL+
Sbjct: 302 FGPLTDLVFAFANQLLPLEMDDAETGLLSAICLICGDRQDLEQPDRVDMLQEPLLEALKV 361
Query: 379 YEAGQHMEDPRRAGKMLMTLPLLRQTSTKAVQHFYNIKLEGKVPMHKLFLEMLE 432
Y + P KMLM + LR S K + +K+E M L EMLE
Sbjct: 362 YVRKRRPSRPHMFPKMLMKITDLRSISAKGAERVITLKMEIPGSMPPLIQEMLE 415
>gi|4506419 retinoic acid receptor, alpha isoform 1 [Homo sapiens]
Length = 462
Score = 188 bits (477), Expect = 9e-48
Identities = 129/414 (31%), Positives = 197/414 (47%), Gaps = 26/414 (6%)
Query: 42 SGSYSSTMNGHQNGLDSPPL-YPSAPILGGSGPVRKL-----------YDDCSSTIVEDP 89
S S + GH NG PP + P+LGG P L Y S +E
Sbjct: 5 SSSCPTPGGGHLNGYPVPPYAFFFPPMLGGLSPPGALTTLQHQLPVSGYSTPSPATIETQ 64
Query: 90 QTKCEYMLNSMPK--------RLCLVCGDIASGYHYGVASCEACKAFFKRTIQGNIEYSC 141
+ E ++ S P + C VC D +SGYHYGV++CE CK FF+R+IQ N+ Y+C
Sbjct: 65 SSSSEEIVPSPPSPPPLPRIYKPCFVCQDKSSGYHYGVSACEGCKGFFRRSIQKNMVYTC 124
Query: 142 PATNECEITKRRRKSCQACRFMKCLKVGMLKEGVRLDRVRGGRQKYKRRIDAENSPYLNP 201
C I K R CQ CR KC +VGM KE VR DR + ++K + + S L P
Sbjct: 125 HRDKNCIINKVTRNRCQYCRLQKCFEVGMSKESVRNDRNK--KKKEVPKPECSESYTLTP 182
Query: 202 ---QLVQPAKKPYNKIVSHLLVAEPEKIYAMPDPTVPDSDIKALTTLCDLADRELVVIIG 258
+L++ +K + + L + V DI +L+ + ++ +
Sbjct: 183 EVGELIEKVRKAHQETFPALCQLGKYTTNNSSEQRV-SLDIDLWDKFSELSTKCIIKTVE 241
Query: 259 WAKHIPGFSTLSLADQMSLLQSAWMEILILGVVYRSLSFEDELVYADDYIMDEDQSKLAG 318
+AK +PGF+TL++ADQ++LL++A ++ILIL + R +D + ++D ++ Q AG
Sbjct: 242 FAKQLPGFTTLTIADQITLLKAACLDILILRICTRYTPEQDTMTFSDGLTLNRTQMHNAG 301
Query: 319 LLDLNNAILQLVKKYKSMKLEKEEFVTLKAIALANSDSMHIEDVEAVQKLQDVLHEALQD 378
L + + + ++++ E L AI L D +E + V LQ+ L EAL+
Sbjct: 302 FGPLTDLVFAFANQLLPLEMDDAETGLLSAICLICGDRQDLEQPDRVDMLQEPLLEALKV 361
Query: 379 YEAGQHMEDPRRAGKMLMTLPLLRQTSTKAVQHFYNIKLEGKVPMHKLFLEMLE 432
Y + P KMLM + LR S K + +K+E M L EMLE
Sbjct: 362 YVRKRRPSRPHMFPKMLMKITDLRSISAKGAERVITLKMEIPGSMPPLIQEMLE 415
>gi|5453822 nuclear receptor subfamily 4, group A, member 2 [Homo
sapiens]
Length = 598
Score = 187 bits (475), Expect = 2e-47
Identities = 114/337 (33%), Positives = 182/337 (54%), Gaps = 11/337 (3%)
Query: 104 LCLVCGDIASGYHYGVASCEACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQACRFM 163
LC VCGD A+ HYGV +CE CK FFKRT+Q N +Y C A C + KRRR CQ CRF
Sbjct: 262 LCAVCGDNAACQHYGVRTCEGCKGFFKRTVQKNAKYVCLANKNCPVDKRRRNRCQYCRFQ 321
Query: 164 KCLKVGMLKEGVRLDRVRG--GRQKYKRRIDAENSPYLNP-QLVQPAKKPYNKIVSHLLV 220
KCL VGM+KE VR D ++G GR K + E SP P L+ + + +
Sbjct: 322 KCLAVGMVKEVVRTDSLKGRRGRLPSKPKSPQEPSPPSPPVSLISALVRAHVDSNPAMTS 381
Query: 221 AEPEKIYAMPDPTVPDSDIKALTTLCDLADRELVVIIGWAKHIPGFSTLSLADQMSLLQS 280
+ + A PD + D + + DL + +I GWA+ IPGF+ L ADQ L +S
Sbjct: 382 LDYSRFQANPDYQMSGDDTQHIQQFYDLLTGSMEIIRGWAEKIPGFADLPKADQDLLFES 441
Query: 281 AWMEILILGVVYRSLSFEDELVYADDYIMDEDQSKLAGLLDLNNAILQLVKKYKSMKLEK 340
A++E+ +L + YRS E +L++ + ++ Q + G + ++I++ ++M ++
Sbjct: 442 AFLELFVLRLAYRSNPVEGKLIFCNGVVLHRLQC-VRGFGEWIDSIVEFSSNLQNMNIDI 500
Query: 341 EEFVTLKAIALANSDSMHIEDVEAVQKLQDVLHEALQDYEAGQH--MEDPRRAGKMLMTL 398
F + A+A+ ++ +++ + V++LQ+ + L+D+ + + P K+L L
Sbjct: 501 SAFSCIAALAMV-TERHGLKEPKRVEELQNKIVNCLKDHVTFNNGGLNRPNYLSKLLGKL 559
Query: 399 PLLRQTSTKAVQHFYNIKLEGKVP----MHKLFLEML 431
P LR T+ +Q + +KLE VP + KLFL+ L
Sbjct: 560 PELRTLCTQGLQRIFYLKLEDLVPPPAIIDKLFLDTL 596
>gi|67459914 retinoic acid receptor, alpha isoform 2 [Homo sapiens]
Length = 457
Score = 181 bits (458), Expect = 2e-45
Identities = 121/386 (31%), Positives = 187/386 (48%), Gaps = 12/386 (3%)
Query: 53 QNGLDSPPLYPS---APILGGSGPVRKLYDDCSSTIVEDPQTKCEYMLNSMPKRLCLVCG 109
+ GL +P Y + P+ GS + S IV P + P C VC
Sbjct: 31 EKGLPAPGPYSTPLRTPLWNGSNHSIETQSSSSEEIVPSPPSPPPLPRIYKP---CFVCQ 87
Query: 110 DIASGYHYGVASCEACKAFFKRTIQGNIEYSCPATNECEITKRRRKSCQACRFMKCLKVG 169
D +SGYHYGV++CE CK FF+R+IQ N+ Y+C C I K R CQ CR KC +VG
Sbjct: 88 DKSSGYHYGVSACEGCKGFFRRSIQKNMVYTCHRDKNCIINKVTRNRCQYCRLQKCFEVG 147
Query: 170 MLKEGVRLDRVRGGRQKYKRRIDAENSPYLNP---QLVQPAKKPYNKIVSHLLVAEPEKI 226
M KE VR DR + ++K + + S L P +L++ +K + + L
Sbjct: 148 MSKESVRNDRNK--KKKEVPKPECSESYTLTPEVGELIEKVRKAHQETFPALCQLGKYTT 205
Query: 227 YAMPDPTVPDSDIKALTTLCDLADRELVVIIGWAKHIPGFSTLSLADQMSLLQSAWMEIL 286
+ V DI +L+ + ++ + +AK +PGF+TL++ADQ++LL++A ++IL
Sbjct: 206 NNSSEQRV-SLDIDLWDKFSELSTKCIIKTVEFAKQLPGFTTLTIADQITLLKAACLDIL 264
Query: 287 ILGVVYRSLSFEDELVYADDYIMDEDQSKLAGLLDLNNAILQLVKKYKSMKLEKEEFVTL 346
IL + R +D + ++D ++ Q AG L + + + ++++ E L
Sbjct: 265 ILRICTRYTPEQDTMTFSDGLTLNRTQMHNAGFGPLTDLVFAFANQLLPLEMDDAETGLL 324
Query: 347 KAIALANSDSMHIEDVEAVQKLQDVLHEALQDYEAGQHMEDPRRAGKMLMTLPLLRQTST 406
AI L D +E + V LQ+ L EAL+ Y + P KMLM + LR S
Sbjct: 325 SAICLICGDRQDLEQPDRVDMLQEPLLEALKVYVRKRRPSRPHMFPKMLMKITDLRSISA 384
Query: 407 KAVQHFYNIKLEGKVPMHKLFLEMLE 432
K + +K+E M L EMLE
Sbjct: 385 KGAERVITLKMEIPGSMPPLIQEMLE 410
>gi|66528642 nuclear receptor subfamily 3, group C, member 1 isoform
beta [Homo sapiens]
Length = 742
Score = 180 bits (457), Expect = 2e-45
Identities = 102/273 (37%), Positives = 150/273 (54%), Gaps = 4/273 (1%)
Query: 86 VEDPQTKCEYMLNSMPKRLCLVCGDIASGYHYGVASCEACKAFFKRTIQGNIEYSCPATN 145
V P + P +LCLVC D ASG HYGV +C +CK FFKR ++G Y C N
Sbjct: 402 VSSPPSSSSTATTGPPPKLCLVCSDEASGCHYGVLTCGSCKVFFKRAVEGQHNYLCAGRN 461
Query: 146 ECEITKRRRKSCQACRFMKCLKVGMLKEGVRLDRVRGGRQKYKRRIDAENSPYLNPQLVQ 205
+C I K RRK+C ACR+ KCL+ GM E + + G Q+ + E S + +
Sbjct: 462 DCIIDKIRRKNCPACRYRKCLQAGMNLEARKTKKKIKGIQQATTGVSQETSENPGNKTIV 521
Query: 206 PAKKPY--NKIVSHLLVAEPEKIYAMPDPTVPDSDIKALTTLCDLADRELVVIIGWAKHI 263
PA P +VS L V EPE +YA D +VPDS + +TTL L R+++ + WAK I
Sbjct: 522 PATLPQLTPTLVSLLEVIEPEVLYAGYDSSVPDSTWRIMTTLNMLGGRQVIAAVKWAKAI 581
Query: 264 PGFSTLSLADQMSLLQSAWMEILILGVVYRSL--SFEDELVYADDYIMDEDQSKLAGLLD 321
PGF L L DQM+LLQ +WM ++ + +RS S + L +A D I++E + L + D
Sbjct: 582 PGFRNLHLDDQMTLLQYSWMFLMAFALGWRSYRQSSANLLCFAPDLIINEQRMTLPCMYD 641
Query: 322 LNNAILQLVKKYKSMKLEKEEFVTLKAIALANS 354
+L + + +++ EE++ +K + L +S
Sbjct: 642 QCKHMLYVSSELHRLQVSYEEYLCMKTLLLLSS 674
>gi|66528611 nuclear receptor subfamily 3, group C, member 1 isoform
alpha [Homo sapiens]
Length = 777
Score = 180 bits (457), Expect = 2e-45
Identities = 102/273 (37%), Positives = 150/273 (54%), Gaps = 4/273 (1%)
Query: 86 VEDPQTKCEYMLNSMPKRLCLVCGDIASGYHYGVASCEACKAFFKRTIQGNIEYSCPATN 145
V P + P +LCLVC D ASG HYGV +C +CK FFKR ++G Y C N
Sbjct: 402 VSSPPSSSSTATTGPPPKLCLVCSDEASGCHYGVLTCGSCKVFFKRAVEGQHNYLCAGRN 461
Query: 146 ECEITKRRRKSCQACRFMKCLKVGMLKEGVRLDRVRGGRQKYKRRIDAENSPYLNPQLVQ 205
+C I K RRK+C ACR+ KCL+ GM E + + G Q+ + E S + +
Sbjct: 462 DCIIDKIRRKNCPACRYRKCLQAGMNLEARKTKKKIKGIQQATTGVSQETSENPGNKTIV 521
Query: 206 PAKKPY--NKIVSHLLVAEPEKIYAMPDPTVPDSDIKALTTLCDLADRELVVIIGWAKHI 263
PA P +VS L V EPE +YA D +VPDS + +TTL L R+++ + WAK I
Sbjct: 522 PATLPQLTPTLVSLLEVIEPEVLYAGYDSSVPDSTWRIMTTLNMLGGRQVIAAVKWAKAI 581
Query: 264 PGFSTLSLADQMSLLQSAWMEILILGVVYRSL--SFEDELVYADDYIMDEDQSKLAGLLD 321
PGF L L DQM+LLQ +WM ++ + +RS S + L +A D I++E + L + D
Sbjct: 582 PGFRNLHLDDQMTLLQYSWMFLMAFALGWRSYRQSSANLLCFAPDLIINEQRMTLPCMYD 641
Query: 322 LNNAILQLVKKYKSMKLEKEEFVTLKAIALANS 354
+L + + +++ EE++ +K + L +S
Sbjct: 642 QCKHMLYVSSELHRLQVSYEEYLCMKTLLLLSS 674
>gi|66528586 nuclear receptor subfamily 3, group C, member 1 isoform
alpha [Homo sapiens]
Length = 777
Score = 180 bits (457), Expect = 2e-45
Identities = 102/273 (37%), Positives = 150/273 (54%), Gaps = 4/273 (1%)
Query: 86 VEDPQTKCEYMLNSMPKRLCLVCGDIASGYHYGVASCEACKAFFKRTIQGNIEYSCPATN 145
V P + P +LCLVC D ASG HYGV +C +CK FFKR ++G Y C N
Sbjct: 402 VSSPPSSSSTATTGPPPKLCLVCSDEASGCHYGVLTCGSCKVFFKRAVEGQHNYLCAGRN 461
Query: 146 ECEITKRRRKSCQACRFMKCLKVGMLKEGVRLDRVRGGRQKYKRRIDAENSPYLNPQLVQ 205
+C I K RRK+C ACR+ KCL+ GM E + + G Q+ + E S + +
Sbjct: 462 DCIIDKIRRKNCPACRYRKCLQAGMNLEARKTKKKIKGIQQATTGVSQETSENPGNKTIV 521
Query: 206 PAKKPY--NKIVSHLLVAEPEKIYAMPDPTVPDSDIKALTTLCDLADRELVVIIGWAKHI 263
PA P +VS L V EPE +YA D +VPDS + +TTL L R+++ + WAK I
Sbjct: 522 PATLPQLTPTLVSLLEVIEPEVLYAGYDSSVPDSTWRIMTTLNMLGGRQVIAAVKWAKAI 581
Query: 264 PGFSTLSLADQMSLLQSAWMEILILGVVYRSL--SFEDELVYADDYIMDEDQSKLAGLLD 321
PGF L L DQM+LLQ +WM ++ + +RS S + L +A D I++E + L + D
Sbjct: 582 PGFRNLHLDDQMTLLQYSWMFLMAFALGWRSYRQSSANLLCFAPDLIINEQRMTLPCMYD 641
Query: 322 LNNAILQLVKKYKSMKLEKEEFVTLKAIALANS 354
+L + + +++ EE++ +K + L +S
Sbjct: 642 QCKHMLYVSSELHRLQVSYEEYLCMKTLLLLSS 674
>gi|66528563 nuclear receptor subfamily 3, group C, member 1 isoform
alpha [Homo sapiens]
Length = 777
Score = 180 bits (457), Expect = 2e-45
Identities = 102/273 (37%), Positives = 150/273 (54%), Gaps = 4/273 (1%)
Query: 86 VEDPQTKCEYMLNSMPKRLCLVCGDIASGYHYGVASCEACKAFFKRTIQGNIEYSCPATN 145
V P + P +LCLVC D ASG HYGV +C +CK FFKR ++G Y C N
Sbjct: 402 VSSPPSSSSTATTGPPPKLCLVCSDEASGCHYGVLTCGSCKVFFKRAVEGQHNYLCAGRN 461
Query: 146 ECEITKRRRKSCQACRFMKCLKVGMLKEGVRLDRVRGGRQKYKRRIDAENSPYLNPQLVQ 205
+C I K RRK+C ACR+ KCL+ GM E + + G Q+ + E S + +
Sbjct: 462 DCIIDKIRRKNCPACRYRKCLQAGMNLEARKTKKKIKGIQQATTGVSQETSENPGNKTIV 521
Query: 206 PAKKPY--NKIVSHLLVAEPEKIYAMPDPTVPDSDIKALTTLCDLADRELVVIIGWAKHI 263
PA P +VS L V EPE +YA D +VPDS + +TTL L R+++ + WAK I
Sbjct: 522 PATLPQLTPTLVSLLEVIEPEVLYAGYDSSVPDSTWRIMTTLNMLGGRQVIAAVKWAKAI 581
Query: 264 PGFSTLSLADQMSLLQSAWMEILILGVVYRSL--SFEDELVYADDYIMDEDQSKLAGLLD 321
PGF L L DQM+LLQ +WM ++ + +RS S + L +A D I++E + L + D
Sbjct: 582 PGFRNLHLDDQMTLLQYSWMFLMAFALGWRSYRQSSANLLCFAPDLIINEQRMTLPCMYD 641
Query: 322 LNNAILQLVKKYKSMKLEKEEFVTLKAIALANS 354
+L + + +++ EE++ +K + L +S
Sbjct: 642 QCKHMLYVSSELHRLQVSYEEYLCMKTLLLLSS 674
>gi|66528530 nuclear receptor subfamily 3, group C, member 1 isoform
alpha [Homo sapiens]
Length = 777
Score = 180 bits (457), Expect = 2e-45
Identities = 102/273 (37%), Positives = 150/273 (54%), Gaps = 4/273 (1%)
Query: 86 VEDPQTKCEYMLNSMPKRLCLVCGDIASGYHYGVASCEACKAFFKRTIQGNIEYSCPATN 145
V P + P +LCLVC D ASG HYGV +C +CK FFKR ++G Y C N
Sbjct: 402 VSSPPSSSSTATTGPPPKLCLVCSDEASGCHYGVLTCGSCKVFFKRAVEGQHNYLCAGRN 461
Query: 146 ECEITKRRRKSCQACRFMKCLKVGMLKEGVRLDRVRGGRQKYKRRIDAENSPYLNPQLVQ 205
+C I K RRK+C ACR+ KCL+ GM E + + G Q+ + E S + +
Sbjct: 462 DCIIDKIRRKNCPACRYRKCLQAGMNLEARKTKKKIKGIQQATTGVSQETSENPGNKTIV 521
Query: 206 PAKKPY--NKIVSHLLVAEPEKIYAMPDPTVPDSDIKALTTLCDLADRELVVIIGWAKHI 263
PA P +VS L V EPE +YA D +VPDS + +TTL L R+++ + WAK I
Sbjct: 522 PATLPQLTPTLVSLLEVIEPEVLYAGYDSSVPDSTWRIMTTLNMLGGRQVIAAVKWAKAI 581
Query: 264 PGFSTLSLADQMSLLQSAWMEILILGVVYRSL--SFEDELVYADDYIMDEDQSKLAGLLD 321
PGF L L DQM+LLQ +WM ++ + +RS S + L +A D I++E + L + D
Sbjct: 582 PGFRNLHLDDQMTLLQYSWMFLMAFALGWRSYRQSSANLLCFAPDLIINEQRMTLPCMYD 641
Query: 322 LNNAILQLVKKYKSMKLEKEEFVTLKAIALANS 354
+L + + +++ EE++ +K + L +S
Sbjct: 642 QCKHMLYVSSELHRLQVSYEEYLCMKTLLLLSS 674
>gi|4504133 nuclear receptor subfamily 3, group C, member 1 isoform
alpha [Homo sapiens]
Length = 777
Score = 180 bits (457), Expect = 2e-45
Identities = 102/273 (37%), Positives = 150/273 (54%), Gaps = 4/273 (1%)
Query: 86 VEDPQTKCEYMLNSMPKRLCLVCGDIASGYHYGVASCEACKAFFKRTIQGNIEYSCPATN 145
V P + P +LCLVC D ASG HYGV +C +CK FFKR ++G Y C N
Sbjct: 402 VSSPPSSSSTATTGPPPKLCLVCSDEASGCHYGVLTCGSCKVFFKRAVEGQHNYLCAGRN 461
Query: 146 ECEITKRRRKSCQACRFMKCLKVGMLKEGVRLDRVRGGRQKYKRRIDAENSPYLNPQLVQ 205
+C I K RRK+C ACR+ KCL+ GM E + + G Q+ + E S + +
Sbjct: 462 DCIIDKIRRKNCPACRYRKCLQAGMNLEARKTKKKIKGIQQATTGVSQETSENPGNKTIV 521
Query: 206 PAKKPY--NKIVSHLLVAEPEKIYAMPDPTVPDSDIKALTTLCDLADRELVVIIGWAKHI 263
PA P +VS L V EPE +YA D +VPDS + +TTL L R+++ + WAK I
Sbjct: 522 PATLPQLTPTLVSLLEVIEPEVLYAGYDSSVPDSTWRIMTTLNMLGGRQVIAAVKWAKAI 581
Query: 264 PGFSTLSLADQMSLLQSAWMEILILGVVYRSL--SFEDELVYADDYIMDEDQSKLAGLLD 321
PGF L L DQM+LLQ +WM ++ + +RS S + L +A D I++E + L + D
Sbjct: 582 PGFRNLHLDDQMTLLQYSWMFLMAFALGWRSYRQSSANLLCFAPDLIINEQRMTLPCMYD 641
Query: 322 LNNAILQLVKKYKSMKLEKEEFVTLKAIALANS 354
+L + + +++ EE++ +K + L +S
Sbjct: 642 QCKHMLYVSSELHRLQVSYEEYLCMKTLLLLSS 674
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.133 0.389
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,182,042
Number of Sequences: 37866
Number of extensions: 802511
Number of successful extensions: 3032
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 127
Number of HSP's successfully gapped in prelim test: 32
Number of HSP's that attempted gapping in prelim test: 2625
Number of HSP's gapped (non-prelim): 285
length of query: 435
length of database: 18,247,518
effective HSP length: 105
effective length of query: 330
effective length of database: 14,271,588
effective search space: 4709624040
effective search space used: 4709624040
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.