Search of human proteins with 45545424

Search of human proteins with 45545424

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|45545424 LISCH protein isoform 2 [Homo sapiens]
         (649 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|45545424 LISCH protein isoform 2 [Homo sapiens]                   1359   0.0  
gi|45505163 LISCH protein isoform 1 [Homo sapiens]                   1310   0.0  
gi|45593136 LISCH protein isoform 3 [Homo sapiens]                    709   0.0  
gi|40786420 immunoglobulin-like domain containing receptor 2 [Ho...   347   2e-95
gi|28557777 immunoglobulin-like domain containing receptor 1 [Ho...   196   6e-50
gi|224548936 hypothetical protein LOC100170229 [Homo sapiens]          59   2e-08
gi|150418009 transforming, acidic coiled-coil containing protein...    54   4e-07
gi|5031561 transmembrane glycoprotein A33 precursor [Homo sapiens]     49   1e-05
gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]        49   1e-05
gi|153251865 hypothetical protein LOC84226 [Homo sapiens]              49   2e-05
gi|4503509 eukaryotic translation initiation factor 3, subunit 1...    48   3e-05
gi|29568103 U1 small nuclear ribonucleoprotein 70 kDa [Homo sapi...    47   5e-05
gi|65301122 MARVEL domain containing 3 isoform 1 [Homo sapiens]        47   7e-05
gi|65293358 MARVEL domain containing 3 isoform 2 [Homo sapiens]        47   7e-05
gi|50083281 KIAA1853 protein [Homo sapiens]                            43   8e-04
gi|71044479 death inducer-obliterator 1 isoform c [Homo sapiens]       43   0.001
gi|154354981 regulating synaptic membrane exocytosis 2 isoform b...    43   0.001
gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens]         43   0.001
gi|14670268 RD RNA-binding protein [Homo sapiens]                      42   0.001
gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo s...    42   0.001
gi|20127499 arginine/serine-rich splicing factor 6 [Homo sapiens]      42   0.002
gi|186700623 Rab-like GTP-binding protein 1 isoform 1 [Homo sapi...    42   0.002
gi|50053795 eukaryotic translation initiation factor 4B [Homo sa...    41   0.004
gi|154354983 regulating synaptic membrane exocytosis 2 isoform a...    41   0.004
gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ...    41   0.004
gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [...    41   0.004
gi|42518065 tight junction protein 2 (zona occludens 2) isoform ...    40   0.005
gi|42518070 tight junction protein 2 (zona occludens 2) isoform ...    40   0.005
gi|38146113 arginine/serine-rich coiled-coil 2 isoform b [Homo s...    40   0.009
gi|47271443 splicing factor, arginine/serine-rich 2 [Homo sapiens]     39   0.011

>gi|45545424 LISCH protein isoform 2 [Homo sapiens]
          Length = 649

 Score = 1359 bits (3518), Expect = 0.0
 Identities = 649/649 (100%), Positives = 649/649 (100%)

Query: 1   MQQDGLGVGTRNGSGKGRSVHPSWPWCAPRPLRYFGRDARARRAQTAAMALLAGGLSRGL 60
           MQQDGLGVGTRNGSGKGRSVHPSWPWCAPRPLRYFGRDARARRAQTAAMALLAGGLSRGL
Sbjct: 1   MQQDGLGVGTRNGSGKGRSVHPSWPWCAPRPLRYFGRDARARRAQTAAMALLAGGLSRGL 60

Query: 61  GSHPAAAGRDAVVFVWLLLSTWCTAPARAIQVTVSNPYHVVILFQPVTLPCTYQMTSTPT 120
           GSHPAAAGRDAVVFVWLLLSTWCTAPARAIQVTVSNPYHVVILFQPVTLPCTYQMTSTPT
Sbjct: 61  GSHPAAAGRDAVVFVWLLLSTWCTAPARAIQVTVSNPYHVVILFQPVTLPCTYQMTSTPT 120

Query: 121 QPIVIWKYKSFCRDRIADAFSPASVDNQLNAQLAAGNPGYNPYVECQDSVRTVRVVATKQ 180
           QPIVIWKYKSFCRDRIADAFSPASVDNQLNAQLAAGNPGYNPYVECQDSVRTVRVVATKQ
Sbjct: 121 QPIVIWKYKSFCRDRIADAFSPASVDNQLNAQLAAGNPGYNPYVECQDSVRTVRVVATKQ 180

Query: 181 GNAVTLGDYYQGRRITITGNADLTFDQTAWGDSGVYYCSVVSAQDLQGNNEAYAELIVLG 240
           GNAVTLGDYYQGRRITITGNADLTFDQTAWGDSGVYYCSVVSAQDLQGNNEAYAELIVLG
Sbjct: 181 GNAVTLGDYYQGRRITITGNADLTFDQTAWGDSGVYYCSVVSAQDLQGNNEAYAELIVLG 240

Query: 241 RTSGVAELLPGFQAGPIEDWLFVVVVCLAAFLIFLLLGICWCQCCPHTCCCYVRCPCCPD 300
           RTSGVAELLPGFQAGPIEDWLFVVVVCLAAFLIFLLLGICWCQCCPHTCCCYVRCPCCPD
Sbjct: 241 RTSGVAELLPGFQAGPIEDWLFVVVVCLAAFLIFLLLGICWCQCCPHTCCCYVRCPCCPD 300

Query: 301 KCCCPEALYAAGKAATSGVPSIYAPSTYAHLSPAKTPPPPAMIPMGPAYNGYPGGYPGDV 360
           KCCCPEALYAAGKAATSGVPSIYAPSTYAHLSPAKTPPPPAMIPMGPAYNGYPGGYPGDV
Sbjct: 301 KCCCPEALYAAGKAATSGVPSIYAPSTYAHLSPAKTPPPPAMIPMGPAYNGYPGGYPGDV 360

Query: 361 DRSSSAGGQGSYVPLLRDTDSSVASEVRSGYRIQASQQDDSMRVLYYMEKELANFDPSRP 420
           DRSSSAGGQGSYVPLLRDTDSSVASEVRSGYRIQASQQDDSMRVLYYMEKELANFDPSRP
Sbjct: 361 DRSSSAGGQGSYVPLLRDTDSSVASEVRSGYRIQASQQDDSMRVLYYMEKELANFDPSRP 420

Query: 421 GPPSGRVERAMSEVTSLHEDDWRSRPSRGPALTPIRDEEWGGHSPRSPRGWDQEPAREQA 480
           GPPSGRVERAMSEVTSLHEDDWRSRPSRGPALTPIRDEEWGGHSPRSPRGWDQEPAREQA
Sbjct: 421 GPPSGRVERAMSEVTSLHEDDWRSRPSRGPALTPIRDEEWGGHSPRSPRGWDQEPAREQA 480

Query: 481 GGGWRARRPRARSVDALDDLTPPSTAESGSRSPTSNGGRSRAYMPPRSRSRDDLYDQDDS 540
           GGGWRARRPRARSVDALDDLTPPSTAESGSRSPTSNGGRSRAYMPPRSRSRDDLYDQDDS
Sbjct: 481 GGGWRARRPRARSVDALDDLTPPSTAESGSRSPTSNGGRSRAYMPPRSRSRDDLYDQDDS 540

Query: 541 RDFPRSRDPHYDDFRSRERPPADPRSHHHRTRDPRDNGSRSGDLPYDGRLLEEAVRKKGS 600
           RDFPRSRDPHYDDFRSRERPPADPRSHHHRTRDPRDNGSRSGDLPYDGRLLEEAVRKKGS
Sbjct: 541 RDFPRSRDPHYDDFRSRERPPADPRSHHHRTRDPRDNGSRSGDLPYDGRLLEEAVRKKGS 600

Query: 601 EERRRPHKEEEEEAYYPPAPPPYSETDSQASRERRLKKNLALSRESLVV 649
           EERRRPHKEEEEEAYYPPAPPPYSETDSQASRERRLKKNLALSRESLVV
Sbjct: 601 EERRRPHKEEEEEAYYPPAPPPYSETDSQASRERRLKKNLALSRESLVV 649


>gi|45505163 LISCH protein isoform 1 [Homo sapiens]
          Length = 630

 Score = 1310 bits (3391), Expect = 0.0
 Identities = 630/649 (97%), Positives = 630/649 (97%), Gaps = 19/649 (2%)

Query: 1   MQQDGLGVGTRNGSGKGRSVHPSWPWCAPRPLRYFGRDARARRAQTAAMALLAGGLSRGL 60
           MQQDGLGVGTRNGSGKGRSVHPSWPWCAPRPLRYFGRDARARRAQTAAMALLAGGLSRGL
Sbjct: 1   MQQDGLGVGTRNGSGKGRSVHPSWPWCAPRPLRYFGRDARARRAQTAAMALLAGGLSRGL 60

Query: 61  GSHPAAAGRDAVVFVWLLLSTWCTAPARAIQVTVSNPYHVVILFQPVTLPCTYQMTSTPT 120
           GSHPAAAGRDAVVFVWLLLSTWCTAPARAIQVTVSNPYHVVILFQPVTLPCTYQMTSTPT
Sbjct: 61  GSHPAAAGRDAVVFVWLLLSTWCTAPARAIQVTVSNPYHVVILFQPVTLPCTYQMTSTPT 120

Query: 121 QPIVIWKYKSFCRDRIADAFSPASVDNQLNAQLAAGNPGYNPYVECQDSVRTVRVVATKQ 180
           QPIVIWKYKSFCRDRIADAFSPASVDNQLNAQLAAGNPGYNPYVECQDSVRTVRVVATKQ
Sbjct: 121 QPIVIWKYKSFCRDRIADAFSPASVDNQLNAQLAAGNPGYNPYVECQDSVRTVRVVATKQ 180

Query: 181 GNAVTLGDYYQGRRITITGNADLTFDQTAWGDSGVYYCSVVSAQDLQGNNEAYAELIVLG 240
           GNAVTLGDYYQGRRITITGNADLTFDQTAWGDSGVYYCSVVSAQDLQGNNEAYAELIVL 
Sbjct: 181 GNAVTLGDYYQGRRITITGNADLTFDQTAWGDSGVYYCSVVSAQDLQGNNEAYAELIVL- 239

Query: 241 RTSGVAELLPGFQAGPIEDWLFVVVVCLAAFLIFLLLGICWCQCCPHTCCCYVRCPCCPD 300
                             DWLFVVVVCLAAFLIFLLLGICWCQCCPHTCCCYVRCPCCPD
Sbjct: 240 ------------------DWLFVVVVCLAAFLIFLLLGICWCQCCPHTCCCYVRCPCCPD 281

Query: 301 KCCCPEALYAAGKAATSGVPSIYAPSTYAHLSPAKTPPPPAMIPMGPAYNGYPGGYPGDV 360
           KCCCPEALYAAGKAATSGVPSIYAPSTYAHLSPAKTPPPPAMIPMGPAYNGYPGGYPGDV
Sbjct: 282 KCCCPEALYAAGKAATSGVPSIYAPSTYAHLSPAKTPPPPAMIPMGPAYNGYPGGYPGDV 341

Query: 361 DRSSSAGGQGSYVPLLRDTDSSVASEVRSGYRIQASQQDDSMRVLYYMEKELANFDPSRP 420
           DRSSSAGGQGSYVPLLRDTDSSVASEVRSGYRIQASQQDDSMRVLYYMEKELANFDPSRP
Sbjct: 342 DRSSSAGGQGSYVPLLRDTDSSVASEVRSGYRIQASQQDDSMRVLYYMEKELANFDPSRP 401

Query: 421 GPPSGRVERAMSEVTSLHEDDWRSRPSRGPALTPIRDEEWGGHSPRSPRGWDQEPAREQA 480
           GPPSGRVERAMSEVTSLHEDDWRSRPSRGPALTPIRDEEWGGHSPRSPRGWDQEPAREQA
Sbjct: 402 GPPSGRVERAMSEVTSLHEDDWRSRPSRGPALTPIRDEEWGGHSPRSPRGWDQEPAREQA 461

Query: 481 GGGWRARRPRARSVDALDDLTPPSTAESGSRSPTSNGGRSRAYMPPRSRSRDDLYDQDDS 540
           GGGWRARRPRARSVDALDDLTPPSTAESGSRSPTSNGGRSRAYMPPRSRSRDDLYDQDDS
Sbjct: 462 GGGWRARRPRARSVDALDDLTPPSTAESGSRSPTSNGGRSRAYMPPRSRSRDDLYDQDDS 521

Query: 541 RDFPRSRDPHYDDFRSRERPPADPRSHHHRTRDPRDNGSRSGDLPYDGRLLEEAVRKKGS 600
           RDFPRSRDPHYDDFRSRERPPADPRSHHHRTRDPRDNGSRSGDLPYDGRLLEEAVRKKGS
Sbjct: 522 RDFPRSRDPHYDDFRSRERPPADPRSHHHRTRDPRDNGSRSGDLPYDGRLLEEAVRKKGS 581

Query: 601 EERRRPHKEEEEEAYYPPAPPPYSETDSQASRERRLKKNLALSRESLVV 649
           EERRRPHKEEEEEAYYPPAPPPYSETDSQASRERRLKKNLALSRESLVV
Sbjct: 582 EERRRPHKEEEEEAYYPPAPPPYSETDSQASRERRLKKNLALSRESLVV 630


>gi|45593136 LISCH protein isoform 3 [Homo sapiens]
          Length = 581

 Score =  709 bits (1830), Expect = 0.0
 Identities = 341/342 (99%), Positives = 342/342 (100%)

Query: 308 LYAAGKAATSGVPSIYAPSTYAHLSPAKTPPPPAMIPMGPAYNGYPGGYPGDVDRSSSAG 367
           +YAAGKAATSGVPSIYAPSTYAHLSPAKTPPPPAMIPMGPAYNGYPGGYPGDVDRSSSAG
Sbjct: 240 VYAAGKAATSGVPSIYAPSTYAHLSPAKTPPPPAMIPMGPAYNGYPGGYPGDVDRSSSAG 299

Query: 368 GQGSYVPLLRDTDSSVASEVRSGYRIQASQQDDSMRVLYYMEKELANFDPSRPGPPSGRV 427
           GQGSYVPLLRDTDSSVASEVRSGYRIQASQQDDSMRVLYYMEKELANFDPSRPGPPSGRV
Sbjct: 300 GQGSYVPLLRDTDSSVASEVRSGYRIQASQQDDSMRVLYYMEKELANFDPSRPGPPSGRV 359

Query: 428 ERAMSEVTSLHEDDWRSRPSRGPALTPIRDEEWGGHSPRSPRGWDQEPAREQAGGGWRAR 487
           ERAMSEVTSLHEDDWRSRPSRGPALTPIRDEEWGGHSPRSPRGWDQEPAREQAGGGWRAR
Sbjct: 360 ERAMSEVTSLHEDDWRSRPSRGPALTPIRDEEWGGHSPRSPRGWDQEPAREQAGGGWRAR 419

Query: 488 RPRARSVDALDDLTPPSTAESGSRSPTSNGGRSRAYMPPRSRSRDDLYDQDDSRDFPRSR 547
           RPRARSVDALDDLTPPSTAESGSRSPTSNGGRSRAYMPPRSRSRDDLYDQDDSRDFPRSR
Sbjct: 420 RPRARSVDALDDLTPPSTAESGSRSPTSNGGRSRAYMPPRSRSRDDLYDQDDSRDFPRSR 479

Query: 548 DPHYDDFRSRERPPADPRSHHHRTRDPRDNGSRSGDLPYDGRLLEEAVRKKGSEERRRPH 607
           DPHYDDFRSRERPPADPRSHHHRTRDPRDNGSRSGDLPYDGRLLEEAVRKKGSEERRRPH
Sbjct: 480 DPHYDDFRSRERPPADPRSHHHRTRDPRDNGSRSGDLPYDGRLLEEAVRKKGSEERRRPH 539

Query: 608 KEEEEEAYYPPAPPPYSETDSQASRERRLKKNLALSRESLVV 649
           KEEEEEAYYPPAPPPYSETDSQASRERRLKKNLALSRESLVV
Sbjct: 540 KEEEEEAYYPPAPPPYSETDSQASRERRLKKNLALSRESLVV 581



 Score =  496 bits (1276), Expect = e-140
 Identities = 241/246 (97%), Positives = 242/246 (98%)

Query: 1   MQQDGLGVGTRNGSGKGRSVHPSWPWCAPRPLRYFGRDARARRAQTAAMALLAGGLSRGL 60
           MQQDGLGVGTRNGSGKGRSVHPSWPWCAPRPLRYFGRDARARRAQTAAMALLAGGLSRGL
Sbjct: 1   MQQDGLGVGTRNGSGKGRSVHPSWPWCAPRPLRYFGRDARARRAQTAAMALLAGGLSRGL 60

Query: 61  GSHPAAAGRDAVVFVWLLLSTWCTAPARAIQVTVSNPYHVVILFQPVTLPCTYQMTSTPT 120
           GSHPAAAGRDAVVFVWLLLSTWCTAPARAIQVTVSNPYHVVILFQPVTLPCTYQMTSTPT
Sbjct: 61  GSHPAAAGRDAVVFVWLLLSTWCTAPARAIQVTVSNPYHVVILFQPVTLPCTYQMTSTPT 120

Query: 121 QPIVIWKYKSFCRDRIADAFSPASVDNQLNAQLAAGNPGYNPYVECQDSVRTVRVVATKQ 180
           QPIVIWKYKSFCRDRIADAFSPASVDNQLNAQLAAGNPGYNPYVECQDSVRTVRVVATKQ
Sbjct: 121 QPIVIWKYKSFCRDRIADAFSPASVDNQLNAQLAAGNPGYNPYVECQDSVRTVRVVATKQ 180

Query: 181 GNAVTLGDYYQGRRITITGNADLTFDQTAWGDSGVYYCSVVSAQDLQGNNEAYAELIVLG 240
           GNAVTLGDYYQGRRITITGNADLTFDQTAWGDSGVYYCSVVSAQDLQGNNEAYAELIVL 
Sbjct: 181 GNAVTLGDYYQGRRITITGNADLTFDQTAWGDSGVYYCSVVSAQDLQGNNEAYAELIVLV 240

Query: 241 RTSGVA 246
             +G A
Sbjct: 241 YAAGKA 246


>gi|40786420 immunoglobulin-like domain containing receptor 2 [Homo
           sapiens]
          Length = 639

 Score =  347 bits (890), Expect = 2e-95
 Identities = 233/615 (37%), Positives = 314/615 (51%), Gaps = 83/615 (13%)

Query: 70  DAVVFVWLLLSTWCTAPARAIQVTVSNPYHVVILFQPVTLPCTYQMTSTPTQPIVIWKYK 129
           D V+  W+ L  W TA    +QVTV +   V +LFQP  L C +  TS+    +V WK+K
Sbjct: 2   DRVLLRWISLF-WLTAMVEGLQVTVPDKKKVAMLFQPTVLRCHFS-TSSHQPAVVQWKFK 59

Query: 130 SFCRDRIADAFSPASVDNQLNAQLAAGNPGYNPYVECQDSVRTVRVVATKQGNAVTLGDY 189
           S+C+DR+ ++   +S   Q    L+  N  ++PY++C DS RTVRVVA+KQG+ VTLGD+
Sbjct: 60  SYCQDRMGESLGMSSTRAQ---SLSKRNLEWDPYLDCLDSRRTVRVVASKQGSTVTLGDF 116

Query: 190 YQGRRITITGNADLTFDQTAWGDSGVYYCSVVSAQDLQGNNEAYAELIVLGRTSGVAELL 249
           Y+GR ITI  +ADL   +  WGDSG+YYC + +  DL+G NE   EL+VLGRT  +A+LL
Sbjct: 117 YRGREITIVHDADLQIGKLMWGDSGLYYCIITTPDDLEGKNEDSVELLVLGRTGLLADLL 176

Query: 250 PGFQAGPIEDWLFVVVVCLAAFLIFLLLGICWCQCCPHTCCCYVRCPCCPDKCCCPEALY 309
           P F    + +W+FV +V L  FL F+L+GICWCQCCPH+CCCYVRCPCCPD CCCP+ALY
Sbjct: 177 PSFAVEIMPEWVFVGLVLLGVFLFFVLVGICWCQCCPHSCCCYVRCPCCPDSCCCPQALY 236

Query: 310 AAGKAATSGVPSIYAPSTYAHLSPAKTPPPPAMIPMGPAYNGYPGGYPGDVDRSSSAGGQ 369
            AGKAA +G    Y PS           P P  IP  P      GG P     SS     
Sbjct: 237 EAGKAAKAG----YPPS-------VSGVPGPYSIPSVPL-----GGAP-----SSGMLMD 275

Query: 370 GSYVPLLRDTDSSVAS-EVRSGYRIQASQQDDSMRVLYYMEKELANFDPSRPGPPSGRVE 428
             + P L  +DS+  S  VR GYRIQA ++ DSM+VLYY+EKELA FDP+R     GR  
Sbjct: 276 KPHPPPLAPSDSTGGSHSVRKGYRIQADKERDSMKVLYYVEKELAQFDPAR--RMRGRYN 333

Query: 429 RAMSEVTSLHEDDWRSRPS----RGPALTPIRDEE-----WG---GHSPRSPRGWDQEPA 476
             +SE++SLHE+D   R S    R        D E     W    G S  + RG      
Sbjct: 334 NTISELSSLHEEDSNFRQSFHQMRSKQFPVSGDLESNPDYWSGVMGGSSGASRGPSAMEY 393

Query: 477 REQAGGGWRARRPRARS-------------VDALDDLTPPSTAESGSRSPTSNGGRSR-- 521
            ++    +R  +PR++S               ++D+L   + A+S  + P    G S   
Sbjct: 394 NKEDRESFRHSQPRSKSEMLSRKNFATGVPAVSMDELA--AFADSYGQRPRRADGNSHEA 451

Query: 522 ----AYMPPRSRSRDDLYDQDDSRDF----PRSRDPHYDDFR------SRERPPADPRSH 567
                +    SR+    Y  D   ++     RSR+P  D  R      +R RP  D  +H
Sbjct: 452 RGGSRFERSESRAHSGFYQDDSLEEYYGQRSRSREPLTDADRGWAFSPARRRPAED--AH 509

Query: 568 HHRTRDPRDNGSRSGDLPYDGRLLEEAVRKKGSE--------ERRRPHKEEEEEAYYPPA 619
             R        +   D  Y G   E   R +G+          +R         +YY  +
Sbjct: 510 LPRLVSRTPGTAPKYDHSYLGSARERQARPEGASRGGSLETPSKRSAQLGPRSASYYAWS 569

Query: 620 PP-PYSETDSQASRE 633
           PP  Y    SQ  +E
Sbjct: 570 PPGTYKAGSSQDDQE 584


>gi|28557777 immunoglobulin-like domain containing receptor 1 [Homo
           sapiens]
          Length = 502

 Score =  196 bits (498), Expect = 6e-50
 Identities = 167/564 (29%), Positives = 226/564 (40%), Gaps = 120/564 (21%)

Query: 76  WLLLSTWCTAPARAIQVTVSNPYHVVILFQPVTLPCTYQMTSTPTQPIVIWKYKSFCRDR 135
           WLLL TW  A   ++ VTV +    V LF  + L C Y  ++     +V W++KSFC+D 
Sbjct: 10  WLLLCTWLPAGCLSLLVTVQHTERYVTLFASIILKCDYTTSAQLQDVVVTWRFKSFCKDP 69

Query: 136 IADAFSPASVDNQLNAQLAAGNPGYNPYVECQDSVRTVRVVATKQG-NAVTLGDYYQGRR 194
           I D +S +          AA + G +P  +C D+ R VR+VA ++G N   LG  Y+ R+
Sbjct: 70  IFDYYSAS--------YQAALSLGQDPSNDCNDNQREVRIVAQRRGQNEPVLGVDYRQRK 121

Query: 195 ITITGNADLTFDQTAWGDSGVYYCSVVSAQDLQGNNEAYAELIVLGRTSGVAELLPGFQA 254
           ITI   ADL  ++  W D GVYYC++ +  D  G+ +   +LIVL               
Sbjct: 122 ITIQNRADLVINEVMWWDHGVYYCTIEAPGDTSGDPDKEVKLIVL--------------- 166

Query: 255 GPIEDWLFVVVVCLAAFLIFLLLGICWCQCCPHTCCCYVRCPCCPDKCCCPE-------A 307
                WL V+ + L A L+ LL+G+CWCQCCP  CCCY+RCPCCP  CCCPE       +
Sbjct: 167 ----HWLTVIFIILGALLLLLLIGVCWCQCCPQYCCCYIRCPCCPAHCCCPEEDLSLPSS 222

Query: 308 LYAAGKAATSGVPSI------YAPSTYAHLSPAKTPPPPAMIPMGPAYNGYPGGYPGDVD 361
           L       T+  P I      Y      +L+ A+  PP              G +     
Sbjct: 223 LPQMPMTQTTNQPPIANGVLEYLEKELRNLNLAQPLPP-----------DLKGRFGHPCS 271

Query: 362 RSSSAGGQG------SYVPLLRDTDSSVASEVRSGYRIQASQQDDSMRVLYYMEKELANF 415
             SS G +          PL+RD  SS              +  DS      + ++    
Sbjct: 272 MLSSLGSEVVERRIIHLPPLIRDLSSS-------------RRTSDS------LHQQWLTP 312

Query: 416 DPSRPGPPSGRVERAMSEVTSLHEDDWRSRPSRGPALTPIR----DEEWGG--HSPR--- 466
            PSRP     R  R+       H++       RGP    +     D  W G   S R   
Sbjct: 313 IPSRPW--DLREGRSHHHYPDFHQE----LQDRGPKSWALERRELDPSWSGRHRSSRLNG 366

Query: 467 SPRGWDQE------PAREQAGGGWRARRPRARSVDALDDLTPPSTAESGSRSPTSNGGRS 520
           SP  W         P+  +A   WR   P  RS    +    PS  ES  R       R 
Sbjct: 367 SPIHWSDRDSLSDVPSSSEA--RWRPSHPPFRS-RCQERPRRPSPRESTQRH--GRRRRH 421

Query: 521 RAYMPPRSRSRDDLYDQDDSRDFPRSRDPHYDDFRSRERPPADPRSHHHRTRDPRDNGSR 580
           R+Y PP          ++D    P+S   H     S   P   P S+      P  N   
Sbjct: 422 RSYSPPLPSGLSSWSSEEDKERQPQSWRAHRRGSHSPHWPEEKPPSYRSLDITPGKNS-- 479

Query: 581 SGDLPYDGRLLEEAVRKKGSEERR 604
                          RKKGS ERR
Sbjct: 480 ---------------RKKGSVERR 488


>gi|224548936 hypothetical protein LOC100170229 [Homo sapiens]
          Length = 715

 Score = 58.5 bits (140), Expect = 2e-08
 Identities = 57/226 (25%), Positives = 90/226 (39%), Gaps = 22/226 (9%)

Query: 441 DWRSRPSRGPALTPIRD-----EEWGGHSPRSPRGWDQEPAREQAGGGWRARRPRARSVD 495
           +W   PS+  + +  R      +  G  SPR   G  Q  +  +     R+R P  ++ D
Sbjct: 354 NWSRNPSKERSHSHSRSSSKERDHRGSSSPRKESGRSQSGSPNKQRDHSRSRSPN-KARD 412

Query: 496 ALDDLTPPSTAE-SGSRSPTSNGGRSRAYMPPRSRSRDDLYDQDDSRDFPRSRDPHYDDF 554
                +P    + S SRSP      SR+  P ++R R      + +RD  RSR P+    
Sbjct: 413 RSRSRSPYKARDRSRSRSPNKARDCSRSRSPYKARDRSRSRSPNKARDHSRSRSPNKARD 472

Query: 555 RSRERPPADPRSH-----------HHRTRDP----RDNGSRSGDLPYDGRLLEEAVRKKG 599
           RSR R P+  R H           H R+R P    +   SRS     D R      +++ 
Sbjct: 473 RSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRSRSPSKERQ 532

Query: 600 SEERRRPHKEEEEEAYYPPAPPPYSETDSQASRERRLKKNLALSRE 645
             + R P+KE +      P+           S+ER  ++  + S+E
Sbjct: 533 RRQSRSPNKERDRSQSRSPSEEREHRQSRSPSKERDRRRWRSPSKE 578



 Score = 44.3 bits (103), Expect = 4e-04
 Identities = 57/231 (24%), Positives = 80/231 (34%), Gaps = 25/231 (10%)

Query: 416 DPSRPGPPSGRVERAMSEVTSLHEDDWRSR-PSRGPALTPIRDEEWGGHSPRSPRGWDQE 474
           D SR   PS   + +     S   D  RSR PS+       R         RS     + 
Sbjct: 472 DRSRSRSPSKERDHSQLGSPSKERDHRRSRSPSKERQCRQSRSSSKERDHRRS-----RS 526

Query: 475 PAREQAGGGWRARRPRARSVDALDDLTPPSTAESG-SRSPTSNGGRSRAYMPPRSRSRDD 533
           P++E+     R  R   +  D     +P    E   SRSP+    R R   P + R R  
Sbjct: 527 PSKERQR---RQSRSPNKERDRSQSRSPSEEREHRQSRSPSKERDRRRWRSPSKERERRQ 583

Query: 534 LYDQDDSRDFPRSRDPHYDDFRSRERPPADPRSHHHRTRDPRDNGSRS------------ 581
                + RD  RSR P+     SR R  +  ++ H R+R P   G+ S            
Sbjct: 584 SRSSSEERDHSRSRSPNKQSGYSRPRASSKEKA-HSRSRTPSKEGNHSQSRTSSKESDPS 642

Query: 582 -GDLPYDGRLLEEAVRKKGSEERRRPHK-EEEEEAYYPPAPPPYSETDSQA 630
              +P          R     + R P K      + +P      S+ DSQA
Sbjct: 643 QSTVPRSPDWKRSPTRTSSLSQNRTPSKTSSHSPSTFPSGGQTLSQDDSQA 693



 Score = 38.5 bits (88), Expect = 0.020
 Identities = 48/204 (23%), Positives = 75/204 (36%), Gaps = 21/204 (10%)

Query: 464 SPRSPRGWDQEPAREQAGGGWRARRPRARSVDALDDLTP---PSTAESGSRSPTSNG--- 517
           S   PR   ++  R   G G       A +       TP   PS  +S + SP+S+    
Sbjct: 184 SDSQPRNLSKKSYRPPGGSGIGRSSELAVTPSTAKCQTPTGIPSKEKSDNPSPSSSRKVK 243

Query: 518 --------GRSRAYMPPRSRSRDDLYDQDDSRDFP----RSRDPHYDDFRSRERPPADPR 565
                    R ++Y P    SR   Y+Q  +R  P    +SR P      S++R  +  R
Sbjct: 244 SYGQMIIPSREKSYSPTEMSSRVKSYNQASTRSRPQSHSQSRSPRRSRSGSQKRTHSRVR 303

Query: 566 SHHHRTRDPRDNG-SRSGDLPYDGRLLEEAVRKKGSEER--RRPHKEEEEEAYYPPAPPP 622
           SH  +    R    +R G L   GR  +     KG  +   R P +         P+   
Sbjct: 304 SHSWKRNHSRARSRTRKGILSQMGRHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNPSKER 363

Query: 623 YSETDSQASRERRLKKNLALSRES 646
                  +S+ER  + + +  +ES
Sbjct: 364 SHSHSRSSSKERDHRGSSSPRKES 387



 Score = 35.4 bits (80), Expect = 0.17
 Identities = 58/266 (21%), Positives = 86/266 (32%), Gaps = 63/266 (23%)

Query: 432 SEVTSLHEDDWRSRPSRGPALTPIRDEEWGGHSPRSPRGWDQEPAREQAGG-GWRARRPR 490
           S V S ++   RSRP                 SPR  R   Q+    +     W+    R
Sbjct: 264 SRVKSYNQASTRSRPQSHSQ----------SRSPRRSRSGSQKRTHSRVRSHSWKRNHSR 313

Query: 491 ARSVDALDDLTP-----------PSTAESGSR---------------------------- 511
           ARS      L+               +++ SR                            
Sbjct: 314 ARSRTRKGILSQMGRHSQSRSHSKGKSQNQSRTPRRGRSHNWSRNPSKERSHSHSRSSSK 373

Query: 512 --------SPTSNGGRSRAYMPPRSRSRDDLYDQDDSRDFPRSRDPHYDDFRSRERPPAD 563
                   SP    GRS++  P + R        + +RD  RSR P+    RSR R P  
Sbjct: 374 ERDHRGSSSPRKESGRSQSGSPNKQRDHSRSRSPNKARDRSRSRSPYKARDRSRSRSPNK 433

Query: 564 PRSHHHRTRDP---RDNG-SRSGDLPYDGRLLEEAVRKKGSEERRRPHKEEEEEAYYPPA 619
            R    R+R P   RD   SRS +   D        + +     R P KE +      P+
Sbjct: 434 ARD-CSRSRSPYKARDRSRSRSPNKARDHSRSRSPNKARDRSRSRSPSKERDHSQLGSPS 492

Query: 620 PPPYSETDSQASRERRLKKNLALSRE 645
                      S+ER+ +++ + S+E
Sbjct: 493 KERDHRRSRSPSKERQCRQSRSSSKE 518


>gi|150418009 transforming, acidic coiled-coil containing protein 2
           isoform a [Homo sapiens]
          Length = 2948

 Score = 53.9 bits (128), Expect = 4e-07
 Identities = 82/317 (25%), Positives = 112/317 (35%), Gaps = 49/317 (15%)

Query: 312 GKAATSGVPSIYAPSTYAHLSPAKTPPPPAMIPMGPAYNGYPGGYPGDVDRSS-SAGGQG 370
           G    S  PS+  P+  AH + +    P A IP+           PG   R S S  G  
Sbjct: 399 GGLPVSPEPSLLTPTEEAHPASSLASFPAAQIPIAVEE-------PGSSSRESVSKAG-- 449

Query: 371 SYVPLLRDTDSSVASEVRSGYRIQASQQDDSMRVLYYMEKELANFDPSRPGPPSGRVERA 430
             +P+  D    V      G   Q S            + E    DP     PS +    
Sbjct: 450 --MPVSADAAKEVVDAGLVGLERQVSDLGS--------KGEHPEGDPGEVPAPSPQERGE 499

Query: 431 MSEVTSLHEDDWRSRPSRGPALTP---IRDEEWGGHSPRSPRGWDQEPAREQAGGGWRAR 487
                  HE     +P   P   P     + + G   P  P+    E AR   G    A+
Sbjct: 500 HLNTEQSHE----VQPGVPPPPLPKEQSHEVQPGAPPPPLPKA-PSESARGPPGPTDGAK 554

Query: 488 RPRARSVDALDDLTPPSTAESGSRSP-TSNGGRSRAYMPPRSRSRDDLYDQDDSRDFPRS 546
                     +D T P+ A+ GSRSP  S GG+  A  PP      +L   +DS+ F   
Sbjct: 555 --------VHEDSTSPAVAKEGSRSPGDSPGGKEEAPEPPDGGDPGNL-QGEDSQAFSSK 605

Query: 547 RDPHY-DDFRSRERPPADPRSH--HHRTRDPRDNGSRSGDLPYDGRLLEEAVRKKGSEER 603
           RDP    D  S+    A+ R H   H  + PR  G+   D P+         +   ++  
Sbjct: 606 RDPEVGKDELSKPSSDAESRDHPSSHSAQPPRKGGAGHTDGPHS--------QTAEADAS 657

Query: 604 RRPHKEEEEEAYYPPAP 620
             PHK  EE+   PP P
Sbjct: 658 GLPHKLGEEDPVLPPVP 674


>gi|5031561 transmembrane glycoprotein A33 precursor [Homo sapiens]
          Length = 319

 Score = 49.3 bits (116), Expect = 1e-05
 Identities = 42/172 (24%), Positives = 66/172 (38%), Gaps = 45/172 (26%)

Query: 75  VWLLLSTWCTAPARAIQVTVSNPYHVVILFQ--PVTLPCTYQMTSTPTQPIVIWKYKSFC 132
           +W +L T C        ++V  P  V+   Q   VTLPCTY  +++  + ++ W      
Sbjct: 5   MWPVLWTLCAVRVTVDAISVETPQDVLRASQGKSVTLPCTYHTSTSSREGLIQW------ 58

Query: 133 RDRIADAFSPASVDNQLNAQLAAGNPGYNPYVECQDSVRTVRVVATKQGNAVTLGDYYQG 192
            D++                                   T RVV     N   +      
Sbjct: 59  -DKLL-------------------------------LTHTERVVIWPFSNKNYIHGELYK 86

Query: 193 RRITITGNAD-----LTFDQTAWGDSGVYYCSVVSAQDLQGNNEAYAELIVL 239
            R++I+ NA+     +T DQ    D+G Y CSV    DL+GN ++   L+VL
Sbjct: 87  NRVSISNNAEQSDASITIDQLTMADNGTYECSVSLMSDLEGNTKSRVRLLVL 138


>gi|118572613 splicing coactivator subunit SRm300 [Homo sapiens]
          Length = 2752

 Score = 48.9 bits (115), Expect = 1e-05
 Identities = 69/231 (29%), Positives = 83/231 (35%), Gaps = 34/231 (14%)

Query: 413 ANFDPSRPGPPSGRVERAMSEVTSLHEDDWRSRP-------SRGPALTPIRD-EEWG-GH 463
           A  D S    PS R+ R+ S  T+         P       SR P     R  + WG   
Sbjct: 467 AKRDKSHSHTPSRRMGRSRSPATAKRGRSRSRTPTKRGHSRSRSPQWRRSRSAQRWGRSR 526

Query: 464 SP------RSPR--GWDQEPAREQAGGGWRARRPRARSVDALD-----DLTPPSTAESGS 510
           SP      RSP+  GW +    ++ G    ARR R+ S            TP     S S
Sbjct: 527 SPQRRGRSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRS 586

Query: 511 RSPTSNGGRSRAYMPPRSRSRDDLYDQDDSRDFPRSRDPHYDDFRSRERPPADPRSHHHR 570
           R+P     RSR     RSRSR         R   RSR P     RSR R P   RS   R
Sbjct: 587 RTPARRRSRSRTPTRRRSRSRTPA-----RRGRSRSRTPARR--RSRTRSPVRRRS---R 636

Query: 571 TRDP--RDNGSRSGDLPYDGRLLEEAVRKKGSEERRRPHKEEEEEAYYPPA 619
           +R P  R   SRS      GR       ++G    R P +         PA
Sbjct: 637 SRSPARRSGRSRSRTPARRGRSRSRTPARRGRSRSRTPARRSGRSRSRTPA 687



 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 61/218 (27%), Positives = 82/218 (37%), Gaps = 27/218 (12%)

Query: 443 RSRPSRGPALTPIRDEEWGGHSPRSPRG--WDQEPA-REQAGGGWRARRPRARSVDALDD 499
           RSR  + P  +  R+ +  G S  + RG    + PA R ++     ARR R+RS      
Sbjct: 533 RSRSPQRPGWSRSRNTQRRGRSRSARRGRSHSRSPATRGRSRSRTPARRGRSRS------ 586

Query: 500 LTPPSTAESGSRSPT---------SNGGRSRAYMPPRSRSRDDLYDQDDSRDFPRSRDPH 550
              P+   S SR+PT         +  GRSR+  P R RSR     +   R   RSR P 
Sbjct: 587 -RTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRSRT----RSPVRRRSRSRSPA 641

Query: 551 YDDFRSRERPPADPRSHHHRTRDPRDNGSRSGDLP--YDGRLLEEAVRKKGSEERRRPHK 608
               RSR R PA  R    R+R P   G      P    GR       ++G    R P +
Sbjct: 642 RRSGRSRSRTPA--RRGRSRSRTPARRGRSRSRTPARRSGRSRSRTPARRGRSRSRTPRR 699

Query: 609 EEEEEAYYPPAPPPYSETDSQASRERRLKKNLALSRES 646
                         +S T  +  R     +    SR S
Sbjct: 700 GRSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTS 737



 Score = 44.7 bits (104), Expect = 3e-04
 Identities = 53/190 (27%), Positives = 66/190 (34%), Gaps = 24/190 (12%)

Query: 418 SRPGPPSGRVERAMSEVTSLHEDDWRSRPSRGPALTPIRDEEWGGHSPRSPRGWDQEPAR 477
           SR   P+ R  R+ +           +R  R  + TP R       SP   R   + PAR
Sbjct: 584 SRSRTPARRRSRSRTPTRRRSRSRTPARRGRSRSRTPARRRS-RTRSPVRRRSRSRSPAR 642

Query: 478 EQAGGGWR--ARRPRARSVDALDDLTPPSTAESGSRSPTSNGGRSRAYMPPRSRSRDDLY 535
                  R  ARR R+RS       TP     S SR+P    GRSR+  P R        
Sbjct: 643 RSGRSRSRTPARRGRSRS------RTPARRGRSRSRTPARRSGRSRSRTPAR-------- 688

Query: 536 DQDDSRDFPRSRDPHYDDFRSRERPPADPRSHHHRTRDPRDNGSRSGDLPYDGRLLEEAV 595
                R   RSR P     RSR R        H RT   R     S +     R  +   
Sbjct: 689 -----RGRSRSRTPRRG--RSRSRSLVRRGRSHSRTPQRRGRSGSSSERKNKSRTSQRRS 741

Query: 596 RKKGSEERRR 605
           R   S E ++
Sbjct: 742 RSNSSPEMKK 751



 Score = 38.1 bits (87), Expect = 0.026
 Identities = 48/183 (26%), Positives = 71/183 (38%), Gaps = 22/183 (12%)

Query: 464  SPRSPRGWDQ--EPAREQAGGGWR------ARRP---RARSVDALD-DLTPPSTAESGSR 511
            SP SP   ++   P RE++G          AR P   R+RS  + + D+ P ++ +  S 
Sbjct: 1499 SPSSPELNNKCLTPQRERSGSESSVDQKTVARTPLGQRSRSGSSQELDVKPSASPQERSE 1558

Query: 512  SPTSNGGRSRAYMPPRSRSRDDLYDQDDSRD--FPRSRDPHYDDFRSRERPPADPRSHHH 569
            S +S   +++   P R RSR     + DS+    PR R         +++P A PR+   
Sbjct: 1559 SDSSPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPR-RSRSGSSPEVKDKPRAAPRAQSG 1617

Query: 570  RTRDPRDNGSRSGDLPYDGRLLEEAVRKKGSEERRRPHKEEEEEAYYPPAPPPYSETDSQ 629
                P              R L    R   S + R P  E        P  PP S T  +
Sbjct: 1618 SDSSPEPKAPAP-------RALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARR 1670

Query: 630  ASR 632
             SR
Sbjct: 1671 GSR 1673



 Score = 37.4 bits (85), Expect = 0.044
 Identities = 56/224 (25%), Positives = 79/224 (35%), Gaps = 31/224 (13%)

Query: 418  SRPGPPSGRVERAMSEVTSLHEDDWRSRP-------SRGPALTPIRDEEWGGHSPRSPRG 470
            SR  P S R  R+ + VT       R+ P       SR P +T  R       + R  R 
Sbjct: 1890 SRTSPVSRRRSRSRTSVTRRRSRS-RASPVSRRRSRSRTPPVTRRRSRSRTPTTRRRSRS 1948

Query: 471  WDQEPAREQAGGGWRARRPRARSVDALDDLTPPSTAESGSRSPTSNGGRSRAYMPPRSRS 530
                  R ++    R+R P      +    +P +   S SR+      RSR+   P +R 
Sbjct: 1949 RTPPVTRRRS----RSRTPPVTRRRSRSRTSPITRRRSRSRTSPVTRRRSRSRTSPVTRR 2004

Query: 531  RDDLYDQDDSRDFPRSRDPHYDDFRSRERPPADPRSHHHRTRDPRDNGSRSGDLPYDGRL 590
            R        +R   RSR P     RSR R P  PR    R+R P                
Sbjct: 2005 RSRSRTSPVTRRRSRSRTPPAIRRRSRSRTPLLPRK-RSRSRSPL--------------- 2048

Query: 591  LEEAVRKKGSEERRRPHKEEEEEAYYPPAPPPYSETDSQASRER 634
               A+R++      R  + +      PPA    S + S + R R
Sbjct: 2049 ---AIRRRSRSRTPRTARGKRSLTRSPPAIRRRSASGSSSDRSR 2089



 Score = 36.2 bits (82), Expect = 0.097
 Identities = 57/234 (24%), Positives = 77/234 (32%), Gaps = 50/234 (21%)

Query: 453  TPIRDEEWGGHSPRSPRGWDQEPAREQAGG---------GWRARRPRARSVDALDDL--T 501
            TP R+      SP    G  + P+R    G         G  +R   + S   + D+  T
Sbjct: 1413 TPSRERSSSASSPEMKDGLPRTPSRRSRSGSSPGLRDGSGTPSRHSLSGSSPGMKDIPRT 1472

Query: 502  P----------------PSTAESGSRSPTSNGGRSRAYMPPRSRS-RDDLYDQDDSRDFP 544
            P                P T    SRSP+S    ++   P R RS  +   DQ      P
Sbjct: 1473 PSRGRSECDSSPEPKALPQTPRPRSRSPSSPELNNKCLTPQRERSGSESSVDQKTVARTP 1532

Query: 545  ---RSRDPHYDDFRSRERPPADPRSHHH---------RTRDPRDNGSRSGDLPYDGRLLE 592
               RSR     +     +P A P+             +TR P    SRSG  P       
Sbjct: 1533 LGQRSRSGSSQEL--DVKPSASPQERSESDSSPDSKAKTRTPLRQRSRSGSSP------- 1583

Query: 593  EAVRKKGSEERRRPHKEEEEEAYYPPAPPPYSETDSQASRERRLKKNLALSRES 646
              V  K     RR       E    P   P +++ S +S E +     AL R S
Sbjct: 1584 -EVDSKSRLSPRRSRSGSSPEVKDKPRAAPRAQSGSDSSPEPKAPAPRALPRRS 1636



 Score = 36.2 bits (82), Expect = 0.097
 Identities = 60/224 (26%), Positives = 75/224 (33%), Gaps = 23/224 (10%)

Query: 418  SRPGPPSGRVERAMSEVTSLHEDDWRSRPSRGPALTPIRDEEWGGHSPRSPRGWDQEPAR 477
            SR      R  R      S      R + SR  +    R     G+  RSP    QE +R
Sbjct: 1775 SRSRREKTRTTRRRDRSGSSQSTSRRRQRSRSRSRVTRRRRGGSGYHSRSPAR--QESSR 1832

Query: 478  EQAGGGWRARRPRARSVDALDDLTPPSTAESGSRSPTSNGGRSRAYMPP----RSRSRDD 533
              +    R RR R+R+        P S   S SR+  +   RSR+   P    RSRSR  
Sbjct: 1833 TSS----RRRRGRSRT-------PPTSRKRSRSRTSPAPWKRSRSRASPATHRRSRSRTP 1881

Query: 534  LYDQDDSRDFPRSRDPHYDDFRSRERPPADPRSHHHRTRDPRDNGSRSGDLPYDGRLLEE 593
            L     SR   RSR       RSR R     R    R        SRS   P   R    
Sbjct: 1882 LI----SRRRSRSRTSPVSRRRSRSRTSVTRRRSRSRASPVSRRRSRSRTPPVTRRRSRS 1937

Query: 594  --AVRKKGSEERRRPHKEEEEEAYYPPAPPPYSETDSQASRERR 635
                 ++ S  R  P       +  PP     S + +     RR
Sbjct: 1938 RTPTTRRRSRSRTPPVTRRRSRSRTPPVTRRRSRSRTSPITRRR 1981



 Score = 35.8 bits (81), Expect = 0.13
 Identities = 49/195 (25%), Positives = 67/195 (34%), Gaps = 25/195 (12%)

Query: 411 ELANFDPSRPGPPSGRVERAMSEVTSLHEDDWRSRPSRGPALTPIRDEEWGGH-SPRSPR 469
           E A   PS P     + ++  S        +  S     PA TP+  E  GG   P +  
Sbjct: 325 ETATKQPSSPYEDKDKDKKEKSATRPSPSPERSSTGPEPPAPTPLLAERHGGSPQPLATT 384

Query: 470 GWDQEPAREQAGGGWRARRPRARSVDAL-----DDLTPPST--------AESGSRSP--- 513
              QEP    +       R   +S + L      + +PPS         A S   SP   
Sbjct: 385 PLSQEPVNPPSEASPTRDRSPPKSPEKLPQSSSSESSPPSPQPTKVSRHASSSPESPKPA 444

Query: 514 TSNGGRSRAYMPPRSRS-------RDDLYDQDDSRDFPRSRDPHYDDFRSRERPPADPRS 566
            + G        P S++       RD  +    SR   RSR P     R R R     + 
Sbjct: 445 PAPGSHREISSSPTSKNRSHGRAKRDKSHSHTPSRRMGRSRSPATAK-RGRSRSRTPTKR 503

Query: 567 HHHRTRDPRDNGSRS 581
            H R+R P+   SRS
Sbjct: 504 GHSRSRSPQWRRSRS 518



 Score = 33.1 bits (74), Expect = 0.82
 Identities = 47/199 (23%), Positives = 67/199 (33%), Gaps = 21/199 (10%)

Query: 444  SRPSRGPALTPIRDEEWGGHSPRSPRGWDQEPAREQAGGGWRAR-RPRARSVDALDDLTP 502
            S  S+    TP+R     G SP         P R ++G     + +PRA           
Sbjct: 1562 SPDSKAKTRTPLRQRSRSGSSPEVDSKSRLSPRRSRSGSSPEVKDKPRA----------- 1610

Query: 503  PSTAESGSRSPTSNGGRSRAYMPPRSRS------RDDLYDQDDSRDFPRSRDPHYDDFRS 556
               A+SGS S       +   +P RSRS      R    +   S +      P     R 
Sbjct: 1611 APRAQSGSDSSPEPKAPAPRALPRRSRSGSSSKGRGPSPEGSSSTESSPEHPPKSRTARR 1670

Query: 557  RERPPADPRSHHHRTRDPRDNGSRSGDLPYDGRLLEEAVRKKGSEERRRPHKEEEEEAYY 616
              R   +P++   RT   R +   S +L    RL   +     S E R         +  
Sbjct: 1671 GSRSSPEPKT-KSRTPPRRRSSRSSPELTRKARLSRRSRSASSSPETRSRTPPRHRRS-- 1727

Query: 617  PPAPPPYSETDSQASRERR 635
            P    P     S++SR RR
Sbjct: 1728 PSVSSPEPAEKSRSSRRRR 1746



 Score = 29.6 bits (65), Expect = 9.1
 Identities = 56/231 (24%), Positives = 81/231 (35%), Gaps = 32/231 (13%)

Query: 413 ANFDPSRPGPPSGRVERAMSEVTSLHEDDWRSRPSRGPALTPIRDEEWGGHSPRSPRGWD 472
           ++FDP R    + +      +  SL  +   S  SR P  TP + ++      R  R   
Sbjct: 149 SSFDPQRRAREAKQPAPEPPKPYSLVRE---SSSSRSP--TP-KQKKKKKKKDRGRRSES 202

Query: 473 QEPAREQAGGGWRARRPRARSVDALDDLTPPSTAESGSRSPTSNGGRSRAYMPP------ 526
             P RE+     + ++ R+ S         P T +S  +S      RSR+  P       
Sbjct: 203 SSPRRERKKSS-KKKKHRSESESKKRKHRSP-TPKSKRKSKDKKRKRSRSTTPAPKSRRA 260

Query: 527 -RSRSRDDLYDQDDSRDFPRSR--DPHYDDFRSRERPPAD--------PRSHHHRTRDPR 575
            RS S D     D SR   RS     H      R   PA         P S    T   R
Sbjct: 261 HRSTSADSASSSDTSRSRSRSAAAKTHTTALAGRSPSPASGRRGEGDAPFSEPGTTSTQR 320

Query: 576 ----DNGSRSGDLPYDGRLLEEAVRKKGSEERRRPHKEEEEEAYYPPAPPP 622
               +  ++    PY+ +   +  +K+ S  R  P  E       PPAP P
Sbjct: 321 PSSPETATKQPSSPYEDK---DKDKKEKSATRPSPSPERSSTGPEPPAPTP 368


>gi|153251865 hypothetical protein LOC84226 [Homo sapiens]
          Length = 1984

 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 63/229 (27%), Positives = 85/229 (37%), Gaps = 24/229 (10%)

Query: 435  TSLHEDDWRSRPSRGPALTPIRD----EEWGGHSP--RSPRGWDQEPAREQAGGGWRARR 488
            +S  E  WRS   R     P R      E G HSP  RS RG  Q   R  +      R 
Sbjct: 1599 SSPSERSWRSPSQRNHCSPPERSCHSLSERGLHSPSQRSHRGPSQR--RHHSPSERSHRS 1656

Query: 489  PRARSVDALDDLTPPSTAESGSRSPTSNGGRSRAYMPPRSRSRDDLYDQDDSRDFPRSRD 548
            P  RS  +  +    S ++   R P+     S +    RS S+       + R    S+ 
Sbjct: 1657 PSERSHRSSSERRHRSPSQRSHRGPSERSHCSPSERRHRSPSQRSHRGPSERRHHSPSKR 1716

Query: 549  PHYDDFRSRERPPADPRSHH------HRTRDPRDNGS---RSGDLPYDGRLLEEAVRKKG 599
             H    R   R P++ RSHH      H +   R + S   RS   P +      + R+  
Sbjct: 1717 SHRSPARRSHRSPSE-RSHHSPSERSHHSPSERRHHSPSERSHCSPSERSHCSPSERRHR 1775

Query: 600  SEERRRPHKEEEEEAYYPPAPPPYSETDSQASRERRLKKNLALSRESLV 648
            S   RR H   E+  + P      SE    +  ERR    L  SR SL+
Sbjct: 1776 SPSERRHHSPSEKSHHSP------SERSHHSPSERRRHSPLERSRHSLL 1818



 Score = 33.5 bits (75), Expect = 0.63
 Identities = 57/212 (26%), Positives = 74/212 (34%), Gaps = 19/212 (8%)

Query: 411  ELANFDPS--RPGPPSGRVERAMSEVTSLHEDDWRSRPSRGPALTPIRDEEWGGHSPRSP 468
            E ++  PS  R   PS R  R  SE    H    RS   R PA    R      H   S 
Sbjct: 1683 ERSHCSPSERRHRSPSQRSHRGPSERRH-HSPSKRSH--RSPARRSHRSPSERSHHSPSE 1739

Query: 469  RGWDQEPAREQAGGGWRARRPRARSVDALDDLTPPSTAESGSRSPTSNGGRS---RAYMP 525
            R       R       R   P  RS  +  + +  S +E   RSP+     S   +++  
Sbjct: 1740 RSHHSPSER-------RHHSPSERSHCSPSERSHCSPSERRHRSPSERRHHSPSEKSHHS 1792

Query: 526  PRSRSRDDLYDQDDSRDFPRSRDPHYDDFRSRERPPADPRSHHHRTRDPRDNGSRSGDLP 585
            P  RS       +  R  P  R  H    RS  R P++ RSH    R  R    RS   P
Sbjct: 1793 PSERSHHS--PSERRRHSPLERSRHSLLERSH-RSPSERRSHRSFERSHRRISERSHS-P 1848

Query: 586  YDGRLLEEAVRKKGSEERRRPHKEEEEEAYYP 617
             +   L    R + S   RR H    +  + P
Sbjct: 1849 SEKSHLSPLERSRCSPSERRGHSSSGKTCHSP 1880


>gi|4503509 eukaryotic translation initiation factor 3, subunit 10
            theta, 150/170kDa [Homo sapiens]
          Length = 1382

 Score = 47.8 bits (112), Expect = 3e-05
 Identities = 58/214 (27%), Positives = 75/214 (35%), Gaps = 36/214 (16%)

Query: 416  DPSRPGPPSGRVERAMSEVTSLHEDDWRSRPSRGPALTPIRDEEWGG---HSPRSPRGWD 472
            D SRPGP    V+             WR +          R+E WG      P   R WD
Sbjct: 1162 DDSRPGPWRPLVKPG----------GWREKEKA-------REESWGPPRESRPSEEREWD 1204

Query: 473  QEPAR-------EQAGGGWRARRPRARSVDALDDLTPPSTAESGSRSPTSNGGRSRAYMP 525
            +E  R       E+        R R R VD  D    P       R P       R    
Sbjct: 1205 REKERDRDNQDREENDKDPERERDRERDVDREDRFRRPRDEGGWRRGPAEESSSWRDSSR 1264

Query: 526  PRSRSRDD-LYDQDDSRDFPRSRDPHYDDFRSRERPP----ADPRSHHHRTRDPRDNGSR 580
               R RDD   ++DD RD    RD    D R R  PP     +  S   R  D +D+   
Sbjct: 1265 RDDRDRDDRRRERDDRRDLRERRD--LRDDRDRRGPPLRSEREEVSSWRRADDRKDDRVE 1322

Query: 581  SGDLPYDGRLLEEAVRKKGSEERRRPHKEEEEEA 614
              D P   R+   A+ +    +R R  + E+E+A
Sbjct: 1323 ERDPP--RRVPPPALSRDRERDRDREREGEKEKA 1354



 Score = 33.1 bits (74), Expect = 0.82
 Identities = 56/253 (22%), Positives = 88/253 (34%), Gaps = 44/253 (17%)

Query: 366 AGGQGSYVPLLRDTDSSVASEVRSGYRIQASQQDDSMRVLYYMEKELANFDPSRPGPPSG 425
           A  Q  Y   L+  +  +A E  +    +  Q+ +  R+ YY EKE              
Sbjct: 766 AARQSVYEEKLKQFEERLAEERHNRLEERKRQRKEERRITYYREKE-------------- 811

Query: 426 RVERAMSEVTSLHEDDWRSRPSRGPALTPIRDEEWGGHSPRSPRGWDQEPAREQAGGGWR 485
             E+  +E   L E + R R  R       R+EE   +  R  +  + E  + Q      
Sbjct: 812 EEEQRRAEEQMLKEREERERAERAK-----REEELREYQERVKKLEEVERKKRQRELEIE 866

Query: 486 ARRPRARSVDALDDLTPPSTAESGSRSPTSNGGRSRAYMPPRSRSRDDLYDQDDSRDFPR 545
            R  R      L D        S SR  +  G           R  +  + +    D   
Sbjct: 867 ERERRREEERRLGD-------SSLSRKDSRWG----------DRDSEGTWRKGPEADSEW 909

Query: 546 SRDPHYDDFRSRERPPADPRSHHHRTRDPR---DNGSRSGDLPYDGRLLEEAVRKKGSEE 602
            R P   ++R  E    D RSH      PR   D+  R   L  D    ++ V ++G ++
Sbjct: 910 RRGPPEKEWRRGEGRDED-RSHRRDEERPRRLGDDEDREPSLRPD----DDRVPRRGMDD 964

Query: 603 RRRPHKEEEEEAY 615
            R P +  EE+ +
Sbjct: 965 DRGPRRGPEEDRF 977


>gi|29568103 U1 small nuclear ribonucleoprotein 70 kDa [Homo
           sapiens]
          Length = 437

 Score = 47.0 bits (110), Expect = 5e-05
 Identities = 65/238 (27%), Positives = 91/238 (38%), Gaps = 41/238 (17%)

Query: 386 EVRSGYRIQASQQDDSMRVLYYMEK--ELANFDPSRPGPPSGRVERAMSEVTSLH---ED 440
           ++ S Y+    ++ D  RVL  +E+   +  + P R G   G   R  ++V   H   +D
Sbjct: 156 DMHSAYKHADGKKIDGRRVLVDVERGRTVKGWRPRRLGGGLGGTRRGGADVNIRHSGRDD 215

Query: 441 DWRSRPSRGPALTPIRDEEWGGHSPRSPRGWDQEPAREQAGGGWRARRPRARSVDALDDL 500
             R     GP+  P RD +      R  R  +++  RE+     R RR R+RS D     
Sbjct: 216 TSRYDERPGPSPLPHRDRDRDRERERRERSRERDKERERRRSRSRDRRRRSRSRD----- 270

Query: 501 TPPSTAESGSRSPTSNGGRSRAYMPPRSRSRDDLYDQDDSRDFPRSRDPHYDDFRSRERP 560
                 E   RS              R RS+D   D+D  R   RSR+      R RER 
Sbjct: 271 -----KEERRRS--------------RERSKDK--DRDRKRRSSRSRERAR---RERERK 306

Query: 561 P------ADPRSHHHRTRDPRDNGSRSGDLPYDGRLLEEAVRKKGSEERRRPHKEEEE 612
                   D          P D+G   G+L  DG    E   +    ERRR H+ E E
Sbjct: 307 EELRGGGGDMAEPSEAGDAPPDDGP-PGELGPDGPDGPEEKGRDRDRERRRSHRSERE 363


>gi|65301122 MARVEL domain containing 3 isoform 1 [Homo sapiens]
          Length = 410

 Score = 46.6 bits (109), Expect = 7e-05
 Identities = 49/172 (28%), Positives = 59/172 (34%), Gaps = 37/172 (21%)

Query: 486 ARRPRARSVDALDDLTPPSTAESGSRSPTSNGGRSRAYMPPRSRSRDDLYDQDDSRDFPR 545
           AR PRAR  +       P       +  T +  R R   P R RS D    +D  RD  R
Sbjct: 7   AREPRARPRER-----DPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPER 61

Query: 546 ------SRDPHYDDFRSRER---PPADPRSHHHRTRDPRDNGSRSGDLPYDGRLLEEA-- 594
                 +RD + D  R RER   P   PR   HR   PR       + P   R  + A  
Sbjct: 62  DQERDGNRDRNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSRTRDGARG 121

Query: 595 ---------------------VRKKGSEERRRPHKEEEEEAYYPPAPPPYSE 625
                                 ++KG   RRRP  E   E Y P  P P  E
Sbjct: 122 LTWDAAAPPGPAPWEAPEPPQPQRKGDPGRRRPESEPPSERYLPSTPRPGRE 173


>gi|65293358 MARVEL domain containing 3 isoform 2 [Homo sapiens]
          Length = 401

 Score = 46.6 bits (109), Expect = 7e-05
 Identities = 49/172 (28%), Positives = 59/172 (34%), Gaps = 37/172 (21%)

Query: 486 ARRPRARSVDALDDLTPPSTAESGSRSPTSNGGRSRAYMPPRSRSRDDLYDQDDSRDFPR 545
           AR PRAR  +       P       +  T +  R R   P R RS D    +D  RD  R
Sbjct: 7   AREPRARPRER-----DPGRRPHPDQGRTHDRPRDRPGDPRRKRSSDGNRRRDGDRDPER 61

Query: 546 ------SRDPHYDDFRSRER---PPADPRSHHHRTRDPRDNGSRSGDLPYDGRLLEEA-- 594
                 +RD + D  R RER   P   PR   HR   PR       + P   R  + A  
Sbjct: 62  DQERDGNRDRNRDRERERERERDPDRGPRRDTHRDAGPRAGEHGVWEKPRQSRTRDGARG 121

Query: 595 ---------------------VRKKGSEERRRPHKEEEEEAYYPPAPPPYSE 625
                                 ++KG   RRRP  E   E Y P  P P  E
Sbjct: 122 LTWDAAAPPGPAPWEAPEPPQPQRKGDPGRRRPESEPPSERYLPSTPRPGRE 173


>gi|50083281 KIAA1853 protein [Homo sapiens]
          Length = 611

 Score = 43.1 bits (100), Expect = 8e-04
 Identities = 73/313 (23%), Positives = 105/313 (33%), Gaps = 53/313 (16%)

Query: 362 RSSSAGGQGSYVPLLRDTDSSVASEVRSGYRIQASQQDDSMRVLYYMEKELANFDPSRPG 421
           R    G     +   R+ +S   S+  + +   + Q   +M         L N  P+  G
Sbjct: 305 RGQEKGSPSGGLSKSRELNSGNTSDSGNSFTTSSPQNKGAM---------LENLSPTSRG 355

Query: 422 PPSGR-----VERAMSEVTSLHEDDWRSRPSRGPALTP-IRDEEWGGHSPRSPRGWDQEP 475
             S       +E A  + +SL     RS P +G + +          HS RSP      P
Sbjct: 356 RESRGFQSPCLECAEVKKSSLVPSTARSSPMKGCSRSSSYASTRSSSHSSRSPNP-RASP 414

Query: 476 AREQAGGGWRARRPRARSVDALDDLTPPSTAESGSRSPTSNGGRSR------AYMPPRSR 529
              Q+      +R  +RS        P  +++SG RSP S   RSR       Y P  SR
Sbjct: 415 RYTQSRSTSSEKRSYSRS--------PSYSSKSGKRSPPSRSSRSRRSPSYSRYSP--SR 464

Query: 530 SRDDLYDQDDS----RDFPRSRDPHYDDFRSRERPPADPRSHHHRTR------------- 572
            RD  Y + DS    R+  R R   Y   R R R   D  SH    R             
Sbjct: 465 ERDPKYSEKDSQQRERERARRRRRSYSPMRKRRR---DSPSHLEARRITSARKRPIPYYR 521

Query: 573 -DPRDNGSRSGDLPYDGRLLEEAVRKKGSEERRRPHKEEEEEAYYPPAPPPYSETDSQAS 631
             P  +GS S    +       +  +  S  R R             +    S +    S
Sbjct: 522 PSPSSSGSLSSTSSWYSSSSSRSASRSYSRSRSRSRSRRRSRTRTSSSSSSRSPSPGSRS 581

Query: 632 RERRLKKNLALSR 644
           R R   ++ + SR
Sbjct: 582 RSRSRSRSRSRSR 594



 Score = 37.0 bits (84), Expect = 0.057
 Identities = 49/209 (23%), Positives = 73/209 (34%), Gaps = 37/209 (17%)

Query: 443 RSRPSRGPALTPIRD---EEWGGHSPRSPRG---WDQEPAREQAGGGWRARRPRARSVDA 496
           R+ P   P + P +D   E+ G H    P G   W+++    + G        R  S   
Sbjct: 44  RTEPQNNPVV-PAQDGPSEKLGQHLATEPLGTNSWERDKTCRELGA------TRGHSASH 96

Query: 497 LDDLTPPSTA---ESGSRSPTSNGGRSRAYMPP--------------RSRSRDDLYDQDD 539
             DLTPP ++   +   +S      RS +Y P               R RS         
Sbjct: 97  DKDLTPPPSSRGKKKKKKSTRKKRRRSSSYSPSPVKKKKKKSSKKHKRRRSFSKKRRHSS 156

Query: 540 SRDFPRSRDPHYDDFRSRERPPADPRSHHHR---TRDPRDNGSRSGDLPYDGRLLEEAVR 596
           S    + RD      +SR RP    R  HHR        ++   S +  + GR  EE  +
Sbjct: 157 SSPKSKRRDEKRHKKQSRSRPRKSHRHRHHRCPSRSQSSESRPSSCESRHRGRSPEEGQK 216

Query: 597 KKGSEERRRP----HKEEEEEAYYPPAPP 621
            +    RR          E ++  PP+ P
Sbjct: 217 SRRRHSRRCSKTLCKDSPEAQSSRPPSQP 245



 Score = 30.4 bits (67), Expect = 5.3
 Identities = 26/84 (30%), Positives = 32/84 (38%), Gaps = 5/84 (5%)

Query: 503 PSTAESGSRSPTSNGGRSRAYMPPRSRSRDDLYDQDDSRDFPRSRDPHYDDFRSRERPPA 562
           PS + SGS S TS+      Y    SRS    Y +  SR   R R        S  R P+
Sbjct: 522 PSPSSSGSLSSTSSW-----YSSSSSRSASRSYSRSRSRSRSRRRSRTRTSSSSSSRSPS 576

Query: 563 DPRSHHHRTRDPRDNGSRSGDLPY 586
                  R+R    + SRS    Y
Sbjct: 577 PGSRSRSRSRSRSRSRSRSQSRSY 600



 Score = 29.6 bits (65), Expect = 9.1
 Identities = 49/242 (20%), Positives = 85/242 (35%), Gaps = 25/242 (10%)

Query: 299 PDKCCCPEALYAAGKAATSGVPSIYAPSTYAHLSPAKTPPPPAMIPMGPAYNGYPG--GY 356
           P K C   + YA+ ++++    S    ++  +     T          P+Y+   G    
Sbjct: 385 PMKGCSRSSSYASTRSSSHSSRSPNPRASPRYTQSRSTSSEKRSYSRSPSYSSKSGKRSP 444

Query: 357 PGDVDRSSSAGGQGSYVPLLRDTDSSVASEVRSGYRIQASQQDDSMRVLYYMEKELANFD 416
           P    RS  +     Y P  R+ D               S++D   R      +   ++ 
Sbjct: 445 PSRSSRSRRSPSYSRYSPS-RERDPKY------------SEKDSQQRERERARRRRRSYS 491

Query: 417 PSRP---GPPSGRVERAMSEVTSLHEDDWRSRPSRGPALTPIRDEEWGGHSPRSPRGWDQ 473
           P R      PS    R ++         +R  PS   +L+          S  + R + +
Sbjct: 492 PMRKRRRDSPSHLEARRITSARKRPIPYYRPSPSSSGSLSSTSSWYSSSSSRSASRSYSR 551

Query: 474 EPAREQAGGGWRARRPRARSVDALDDLTPPSTAESGSRSPTSNGGRSRAYMPPRSRSRDD 533
             +R ++      RR R R+  +    +P   + S SRS + +  RSR+    RS S  D
Sbjct: 552 SRSRSRS-----RRRSRTRTSSSSSSRSPSPGSRSRSRSRSRSRSRSRS--QSRSYSSAD 604

Query: 534 LY 535
            Y
Sbjct: 605 SY 606


>gi|71044479 death inducer-obliterator 1 isoform c [Homo sapiens]
          Length = 2240

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 66/228 (28%), Positives = 76/228 (33%), Gaps = 52/228 (22%)

Query: 363  SSSAGGQGSYVPLLRDTDSSVAS-EVRSG----YRIQASQQDDSMRV-LYYMEKELANFD 416
            SSSA GQG       + D   AS + R G    YR Q  +     R  +   EK L   D
Sbjct: 2051 SSSAPGQGP------EADGQWASADFREGKGHEYRNQTFEGRQRERFDVGPKEKPLEEPD 2104

Query: 417  PSRPGPPSGRVERAMSEVTSLHEDDWRSRPSRGPALTPIRDEEWGGHSPR-SPRGWDQEP 475
                     R ER      S  E DW             R  EW  H  + S R WD+  
Sbjct: 2105 AQGRASEDRRRERERGRNWS-RERDWD------------RPREWDRHRDKDSSRDWDRNR 2151

Query: 476  AREQAGGGWRARRPRARSVDALDDLTPPSTAESGSRSPTSNGGRSRAYMPPRSRSRDDLY 535
             R        A R R R  D                       RSR     R R RD   
Sbjct: 2152 ERS-------ANRDREREADR-----------------GKEWDRSRERSRNRERERDRRR 2187

Query: 536  DQDDSRDFPRSRDPHYDDFRSRERPPADPRSHHHRTRDPRDNGSRSGD 583
            D+D SR   R RD   D  R R+R   D        RDP+   SR+ D
Sbjct: 2188 DRDRSRSRERDRDKARDRERGRDR--KDRSKSKESARDPKPEASRASD 2233



 Score = 31.6 bits (70), Expect = 2.4
 Identities = 45/185 (24%), Positives = 60/185 (32%), Gaps = 22/185 (11%)

Query: 462  GHSPRSPRGWDQEPAREQAGGGWRARRPRARSVDALDDLTPPSTAESGSRSPTSNGGRSR 521
            G  P +   W     RE  G  +R +    R  +  D        E     P + G  S 
Sbjct: 2056 GQGPEADGQWASADFREGKGHEYRNQTFEGRQRERFD----VGPKEKPLEEPDAQGRASE 2111

Query: 522  AYMPPRSRSRDDLYDQDDSRDFPRSRDPHYDD------FRSRERP-------PADPRSHH 568
                 R R R+  + ++   D PR  D H D        R+RER         AD     
Sbjct: 2112 DRRRERERGRN--WSRERDWDRPREWDRHRDKDSSRDWDRNRERSANRDREREADRGKEW 2169

Query: 569  HRTRDPRDNGSRSGDLPYD---GRLLEEAVRKKGSEERRRPHKEEEEEAYYPPAPPPYSE 625
             R+R+   N  R  D   D    R  E    K    ER R  K+  +       P P + 
Sbjct: 2170 DRSRERSRNRERERDRRRDRDRSRSRERDRDKARDRERGRDRKDRSKSKESARDPKPEAS 2229

Query: 626  TDSQA 630
              S A
Sbjct: 2230 RASDA 2234


>gi|154354981 regulating synaptic membrane exocytosis 2 isoform b
           [Homo sapiens]
          Length = 1163

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 44/161 (27%), Positives = 68/161 (42%), Gaps = 21/161 (13%)

Query: 501 TPPSTAESGSRSPTSNGGRSRAYMPPRSRSRDDLYDQDDSRD-----------FPRSRDP 549
           +PP+  ++     T N  R R+  P  SR ++  YDQ + R+            PRS   
Sbjct: 23  SPPNILQNELFGQTLNNARKRS--PSVSRDQNRRYDQREEREEYSQYATSDTAMPRSPSD 80

Query: 550 HYDDFRSRERPPADPRSHHHRTRDPRDNGSR-SGDLPYDGRLLE---EAVRKKGSEERRR 605
            Y D RS+  P     S H   RD      R S +   D   +E   E  R++  EE + 
Sbjct: 81  -YADRRSQHEPQFYEDSDHLSYRDSNRRSHRHSKEYIVDDEDVESRDEYERQRREEEYQS 139

Query: 606 PHKEEEEEAYYPPAPPPYSE---TDSQASRERRLKKNLALS 643
            ++ +   A YP  P PY E     ++ SR R  +++  +S
Sbjct: 140 RYRSDPNLARYPVKPQPYEEQMRIHAEVSRARHERRHSDVS 180


>gi|31377595 zinc finger CCCH-type containing 18 [Homo sapiens]
          Length = 953

 Score = 42.7 bits (99), Expect = 0.001
 Identities = 62/228 (27%), Positives = 83/228 (36%), Gaps = 62/228 (27%)

Query: 409 EKELANFDPSRPGPPSGRVERAMSEVTSLHEDDWRSRPSRGPALTPIRDEEW-----GGH 463
           EKE     P  P PPS + E    E             + GP +   R +EW        
Sbjct: 477 EKEKGKPKPRSPQPPSRQAEPPKKEAA-----------TTGPQVK--RADEWKDPWRRSK 523

Query: 464 SPRSPRGWDQEPAREQAGGGWRARRPRARSVDALDDLTPPSTAESGSRSPTSNGGRSRAY 523
           SP+   G    P+R +     R R+  A S  A       +++ S SRS + +G  S   
Sbjct: 524 SPKKKLGVSVSPSRAR-----RRRKTSASSASA------SNSSRSSSRSSSYSGSGS--- 569

Query: 524 MPPRSRSRDDLYDQDDSRDFPRSRDPHYDDFRSRER-----PPADPRSHHHRTRDPRDNG 578
              RSRSR   Y    SR    SR   +   RSR R     P   P    HR    R  G
Sbjct: 570 --SRSRSRSSSYSSYSSRS---SRHSSFSGSRSRSRSFSSSPSPSPTPSPHRP-SIRTKG 623

Query: 579 SRSGDLPYDGRLLEEAVRKKGSEERRRPHKEEEEEAYYPPAPPPYSET 626
             +   P  G+  E++V+K                   PPAPP  ++T
Sbjct: 624 EPA---PPPGKAGEKSVKKPAP----------------PPAPPQATKT 652


>gi|14670268 RD RNA-binding protein [Homo sapiens]
          Length = 380

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 45/146 (30%), Positives = 59/146 (40%), Gaps = 32/146 (21%)

Query: 486 ARRPRARSV--------DALDDLTPPSTAESGSRSPTSNGGRSRAY-------------- 523
           +RRP+ +S+        D L +L P      G   P +  G  R++              
Sbjct: 124 SRRPQRKSLYESFVSSSDRLRELGPDGEEAEG---PGAGDGPPRSFDWGYEERSGAHSSA 180

Query: 524 MPPRSRSRDDLYDQDDSRDFPRSRDPHYDDFRSRERPPADPRSHHHRTRDPRDNGSRSGD 583
            PPRSRSRD  ++++  RD  R RD   D  R RER   D      R RD   +  R  D
Sbjct: 181 SPPRSRSRDRSHERNRDRDRDRERDRDRDRDRDRER---DRDRDRDRDRDRERDRDRERD 237

Query: 584 LPYDGRLLEEAVRKKGS-EERRRPHK 608
              D    E   R+  S  ERR P K
Sbjct: 238 RDRD---REGPFRRSDSFPERRAPRK 260


>gi|38146107 arginine/serine-rich coiled-coil 2 isoform a [Homo
           sapiens]
          Length = 434

 Score = 42.4 bits (98), Expect = 0.001
 Identities = 64/253 (25%), Positives = 92/253 (36%), Gaps = 42/253 (16%)

Query: 406 YYMEKELANFDPSRPGPPSGRVERAMSEVTSLHEDDWRSRPSRGPALTPIRDEEWGGHSP 465
           +Y      + +  R     GR  R+ S        + R   S+  +    + EE      
Sbjct: 39  HYSRSRSRSRERKRKSDNEGRKHRSRSR-----SKEGRRHESKDKSSKKHKSEEHNDKEH 93

Query: 466 RSPRGWDQEPAREQAGGGWRARRPRARSVDALDDLTPPSTAESGSRSPTS---NGGRSRA 522
            S +G  +E       G  R +R   +S          S   S SRS +    +  RSR 
Sbjct: 94  SSDKG--RERLNSSENGEDRHKRKERKS----------SRGRSHSRSRSRERRHRSRSRE 141

Query: 523 YMPPRSRSRDDLYDQDDSRDFPRSRDPHYDDFRSRERPPADPRSHHHRTRDPRDNGSRSG 582
               RSRSR+    +  SR+  +SR    +  R           H HRTR      SRS 
Sbjct: 142 RKKSRSRSRERKKSRSRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRTRSRSR 201

Query: 583 DLPYDGRLLEEAVRKKGSEERRRPHKEEEEEAYYPPAPPPY----SETDSQASRERRLK- 637
           D            RKK  E+ RR  +         P+PPP+    +  D+Q +  RRL+ 
Sbjct: 202 D------------RKKRIEKPRRFSRSLSRT----PSPPPFRGRNTAMDAQEALARRLER 245

Query: 638 -KNLALSRESLVV 649
            K L   RE  +V
Sbjct: 246 AKKLQEQREKEMV 258



 Score = 30.8 bits (68), Expect = 4.1
 Identities = 34/125 (27%), Positives = 48/125 (38%), Gaps = 7/125 (5%)

Query: 528 SRSRDDLYDQDDSRDFPRSRDPHYDDFRSRERP---PADPRSHHHRTRDPRDNGSR--SG 582
           S  RD   +Q +    PR+   HY   RSR R     +D     HR+R     G R  S 
Sbjct: 17  SPDRDKKKEQSEVSVSPRASKHHYSRSRSRSRERKRKSDNEGRKHRSRSRSKEGRRHESK 76

Query: 583 DLPYDGRLLEEAVRKKGSEE--RRRPHKEEEEEAYYPPAPPPYSETDSQASRERRLKKNL 640
           D        EE   K+ S +  R R +  E  E  +       S   S +    R +++ 
Sbjct: 77  DKSSKKHKSEEHNDKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRERRHR 136

Query: 641 ALSRE 645
           + SRE
Sbjct: 137 SRSRE 141



 Score = 30.0 bits (66), Expect = 6.9
 Identities = 31/142 (21%), Positives = 53/142 (37%), Gaps = 11/142 (7%)

Query: 511 RSPTSNGGRSRAYMPPRSRSRDDLYDQDDSRDFPRSRDPHYDDFRSRERPPADPRSHHHR 570
           R+   +  RSR+    RSR R    D +  +   RSR        S+++     +S  H 
Sbjct: 34  RASKHHYSRSRS----RSRERKRKSDNEGRKHRSRSRSKEGRRHESKDKSSKKHKSEEHN 89

Query: 571 TRD-------PRDNGSRSGDLPYDGRLLEEAVRKKGSEERRRPHKEEEEEAYYPPAPPPY 623
            ++        R N S +G+  +  +  + +  +  S  R R  +          +    
Sbjct: 90  DKEHSSDKGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRS 149

Query: 624 SETDSQASRERRLKKNLALSRE 645
            E     SR R  KK+ + SRE
Sbjct: 150 RERKKSRSRSRERKKSRSRSRE 171


>gi|20127499 arginine/serine-rich splicing factor 6 [Homo sapiens]
          Length = 344

 Score = 42.0 bits (97), Expect = 0.002
 Identities = 42/149 (28%), Positives = 55/149 (36%), Gaps = 13/149 (8%)

Query: 504 STAESGSRSPTSNGGRSRAYMPPRSRSRDDLYDQDDSRDFPRSRDPHYDDFRSRERPPAD 563
           S   S SRS  S+  RSR+    RSRSR     +  SR   R         +S+ +P +D
Sbjct: 200 SRRRSRSRSRRSSRSRSRSISKSRSRSRSRSKGRSRSRSKGRK-----SRSKSKSKPKSD 254

Query: 564 PRSHHHRTRDPRDNGSRSGDLPYDGRLLEEAVRKKGSEERRRPHKEEEEEAYYPP----- 618
             SH H     +D   +S          E       S+ R R           PP     
Sbjct: 255 RGSHSHSRSRSKDEYEKSRSRSRSRSPKENGKGDIKSKSRSRSQSRSNSPLPVPPSKARS 314

Query: 619 -APPPYSETDSQASRERRLKKNLALSRES 646
            +PPP   T    SR R   K+ + SR S
Sbjct: 315 VSPPPKRATSRSRSRSR--SKSRSRSRSS 341


>gi|186700623 Rab-like GTP-binding protein 1 isoform 1 [Homo
           sapiens]
          Length = 729

 Score = 41.6 bits (96), Expect = 0.002
 Identities = 93/376 (24%), Positives = 127/376 (33%), Gaps = 51/376 (13%)

Query: 296 PCCPDKCCCPEALYAAGKAATSGVPSIYAPSTYAHLSPAKTPPPPAMIPMGPA-YNGYPG 354
           P  P +   P A  +A     S +  ++  S     +P   PP P     GPA       
Sbjct: 335 PVPPSEALPPPACPSAPAPRRSIISRLFGTSPATEAAPP--PPEPVPAAEGPATVQSVED 392

Query: 355 GYPGD-VDRS-----SSAGGQGSYVPLLRDTDSSVASEVRSGYRIQASQQDDSMRVLYYM 408
             P D +DRS     + A  +          DS    E   G  + A  QDD        
Sbjct: 393 FVPDDRLDRSFLEDTTPARDEKKVGAKAAQQDSDSDGEALGGNPMVAGFQDDV------- 445

Query: 409 EKELANFDPSRPGPPSGRVERAMSEVTSLHEDDWRSRPSRGPALTPIRDEE----WGGHS 464
             +L +     P  P+G V  +     S  E+   + P++GPA  P +  E    W    
Sbjct: 446 --DLEDQPRGSPPLPAGPVP-SQDITLSSEEEAEVAAPTKGPAPAPQQCSEPETKWSSIP 502

Query: 465 PRSPRGWDQEPAREQAG---GGWRARR-PRARSVDALDDLTPPSTAESGSRSPTSNGGRS 520
              PR     P R  A    GG   R  P  RS         P   E  S S +   G  
Sbjct: 503 ASKPRR-GTAPTRTAAPPWPGGVSVRTGPEKRSSTRPPAEMEPGKGEQASSSESDPEGPI 561

Query: 521 RAYMPPRSRSRDDLYDQ--DDSR---DFPRSRDPHYDDFRSRERPPADPRSHHHRTRDPR 575
            A M        D   +  D  R   DFP   DP   D    +  PA+P       + P 
Sbjct: 562 AAQMLSFVMDDPDFESEGSDTQRRADDFPVRDDP--SDVTDEDEGPAEPPPP---PKLPL 616

Query: 576 DNGSRSGDLPYDGRLLEEAVRKKGSEE-------------RRRPHKEEEEEAYYPPAPPP 622
                  D    G  LEEA  K+ SEE             +++  KEEEE+A    +   
Sbjct: 617 PAFRLKNDSDLFGLGLEEAGPKESSEEGKEGKTPSKEKKKKKKKGKEEEEKAAKKKSKHK 676

Query: 623 YSETDSQASRERRLKK 638
            S+   +   ERR ++
Sbjct: 677 KSKDKEEGKEERRRRQ 692


>gi|50053795 eukaryotic translation initiation factor 4B [Homo
           sapiens]
          Length = 611

 Score = 40.8 bits (94), Expect = 0.004
 Identities = 74/303 (24%), Positives = 113/303 (37%), Gaps = 41/303 (13%)

Query: 343 IPMGPAYNGYPGGYPGDV-DRSSSAGGQGSYVPLLRDTDSSVASEVRSGYRIQASQQDDS 401
           +P  P Y  + G  P DV + S     +G  +  +R        E   G+     +  DS
Sbjct: 90  LPKSPPYTAFLGNLPYDVTEESIKEFFRGLNISAVRLPREPSNPERLKGFGYAEFEDLDS 149

Query: 402 M-RVLYYMEKELANF-----------DPSRPGPPSGRVERAMSEVTSLHEDDWRSRPSRG 449
           +   L   E+ L N            D  R     GR     S+ T   + DWR+RP+  
Sbjct: 150 LLSALSLNEESLGNRRIRVDVADQAQDKDRDDRSFGRDRNRDSDKT---DTDWRARPATD 206

Query: 450 PA--LTPIRDEEWGGHSPR----SPR-------GWDQEPAREQAGGGWRARRPRARSVDA 496
                 P R ++  G   R    S R       G+   P R+    G R R     S D 
Sbjct: 207 SFDDYPPRRGDDSFGDKYRDRYDSDRYRDGYRDGYRDGPRRDMDRYGGRDRYDDRGSRDY 266

Query: 497 LDDLTPPSTAESGSRSPTSNGGRSRAYMPPRSRSRDDLYDQDDSRDFPRSRDPHYDDFRS 556
             D    S   SG R+  S   R   Y     R  +D YD+ D R +    D   DD+R 
Sbjct: 267 --DRGYDSRIGSGRRAFGSGYRRDDDYRGGGDRY-EDRYDRRDDRSWSSRDDYSRDDYRR 323

Query: 557 RER-PPADPRSHHHRTRDPRDNGS--------RSGDLPYDGRLLEEAVRKKGSEERRRPH 607
            +R PP  P+ +      P+++ S        R+  +    + ++ A R++  EER +  
Sbjct: 324 DDRGPPQRPKLNLKPRSTPKEDDSSASTSQSTRAASIFGGAKPVDTAAREREVEERLQKE 383

Query: 608 KEE 610
           +E+
Sbjct: 384 QEK 386



 Score = 34.3 bits (77), Expect = 0.37
 Identities = 45/211 (21%), Positives = 77/211 (36%), Gaps = 28/211 (13%)

Query: 456 RDEEWGGHSPRSPRGWDQEPAREQAGGGWRARRPRARSVDALDDLTPP------------ 503
           RD+++ G   R    +D+   R      W +R   +R     DD  PP            
Sbjct: 287 RDDDYRGGGDRYEDRYDRRDDRS-----WSSRDDYSRDDYRRDDRGPPQRPKLNLKPRST 341

Query: 504 --------STAESGSRSPTSNGGRSRAYMPPRSRSRDDLYDQDDSRDFPRSRDPHYDDFR 555
                   ST++S +R+ +  GG        R R  ++   ++  +   R  D    + R
Sbjct: 342 PKEDDSSASTSQS-TRAASIFGGAKPVDTAAREREVEERLQKEQEK-LQRQLDEPKLERR 399

Query: 556 SRERPPADPRSHHHRTRDPRDNGSRSGDLPYDGRLLEEAVRKKGSEERRRPHKEEEEEAY 615
            RER P+  RS   + R+    GS S            A R++  +        +EE+ +
Sbjct: 400 PRERHPSW-RSEETQERERSRTGSESSQTGTSTTSSRNARRRESEKSLENETLNKEEDCH 458

Query: 616 YPPAPPPYSETDSQASRERRLKKNLALSRES 646
            P + PP  +   +       K+N  + R S
Sbjct: 459 SPTSKPPKPDQPLKVMPAPPPKENAWVKRSS 489


>gi|154354983 regulating synaptic membrane exocytosis 2 isoform a
           [Homo sapiens]
          Length = 1349

 Score = 40.8 bits (94), Expect = 0.004
 Identities = 46/185 (24%), Positives = 73/185 (39%), Gaps = 9/185 (4%)

Query: 466 RSPRGWDQEPAREQAGGGWRARRPRARSVDALDDLTPPSTAESGSRSPTSNGGRSRAYMP 525
           + P G    PA E++      R+   ++   +        A    RSP+ +  ++R Y  
Sbjct: 190 QGPSGDLSVPAVEKSRSHGLTRQHSIKNGSGVKHHIASDIASDRKRSPSVSRDQNRRYDQ 249

Query: 526 PRSRSRDDLYDQDDSRDFPRSRDPHYDDFRSRERPPADPRSHHHRTRDPRDNGSR-SGDL 584
              R     Y   D+   PRS    Y D RS+  P     S H   RD      R S + 
Sbjct: 250 REEREEYSQYATSDTA-MPRSPSD-YADRRSQHEPQFYEDSDHLSYRDSNRRSHRHSKEY 307

Query: 585 PYDGRLLE---EAVRKKGSEERRRPHKEEEEEAYYPPAPPPYSE---TDSQASRERRLKK 638
             D   +E   E  R++  EE +  ++ +   A YP  P PY E     ++ SR R  ++
Sbjct: 308 IVDDEDVESRDEYERQRREEEYQSRYRSDPNLARYPVKPQPYEEQMRIHAEVSRARHERR 367

Query: 639 NLALS 643
           +  +S
Sbjct: 368 HSDVS 372


>gi|116089325 splicing factor, arginine/serine-rich 12 isoform a
           [Homo sapiens]
          Length = 624

 Score = 40.8 bits (94), Expect = 0.004
 Identities = 40/158 (25%), Positives = 63/158 (39%), Gaps = 21/158 (13%)

Query: 466 RSPRGWDQEPAREQAGGGWRARRPRARSVDALDDLTPPSTAESGSRSPTSNGGRSRAYMP 525
           + P    Q  A+E      R R  ++    A++  +  S    G RS +    +SR+   
Sbjct: 262 KPPEMTPQAAAKELEEVMKRVREAQSFISAAIEPESGKSNERKGGRSRSHTRSKSRSSSK 321

Query: 526 PRSR---------SRDDLYDQDDSRDFPRSRDPHYDDFRSRERPPADPRSH-HHRTRDPR 575
             SR         SR     +   +D  RS+ PH    +SRER  +  RSH   + +D R
Sbjct: 322 SHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTR 381

Query: 576 DNGSRSGDLPYDGRLLEEAVRKKGSEERRRPHKEEEEE 613
           +               +E V++K  E+ R   KE E+E
Sbjct: 382 EKIKE-----------KERVKEKDREKEREREKEREKE 408



 Score = 38.1 bits (87), Expect = 0.026
 Identities = 38/160 (23%), Positives = 59/160 (36%), Gaps = 17/160 (10%)

Query: 485 RARRPRARSVDALDDLTPPSTAESGSRSPTSNGGRSRAYMPPRSRSRDDLYDQDDSRDFP 544
           R  R R+ S D   D       +   +       R R     + + R    D+D  R+  
Sbjct: 365 RKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKD 424

Query: 545 RSRDPHYDDFRSRERPPADPRSHHHRTRDPRDNGSRSGDLPYDGRLLEEAVRKKGSEERR 604
           R +D   D  R RE+        H + RD      +  +   D     E  R K  +E+R
Sbjct: 425 REKDKEKDREREREK-------EHEKDRD------KEKEKEQDKEKEREKDRSKEIDEKR 471

Query: 605 RPHKEEEEEAYYPPAPPPYSETDSQASRERRLKKNLALSR 644
           +  K+       PP     S     +SRERR +++ + SR
Sbjct: 472 KKDKKSRT----PPRSYNASRRSRSSSRERRRRRSRSSSR 507


>gi|21040255 splicing factor, arginine/serine-rich 12 isoform b
           [Homo sapiens]
          Length = 508

 Score = 40.8 bits (94), Expect = 0.004
 Identities = 40/158 (25%), Positives = 63/158 (39%), Gaps = 21/158 (13%)

Query: 466 RSPRGWDQEPAREQAGGGWRARRPRARSVDALDDLTPPSTAESGSRSPTSNGGRSRAYMP 525
           + P    Q  A+E      R R  ++    A++  +  S    G RS +    +SR+   
Sbjct: 146 KPPEMTPQAAAKELEEVMKRVREAQSFISAAIEPESGKSNERKGGRSRSHTRSKSRSSSK 205

Query: 526 PRSR---------SRDDLYDQDDSRDFPRSRDPHYDDFRSRERPPADPRSH-HHRTRDPR 575
             SR         SR     +   +D  RS+ PH    +SRER  +  RSH   + +D R
Sbjct: 206 SHSRRKRSQSKHRSRSHNRSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRDKRKDTR 265

Query: 576 DNGSRSGDLPYDGRLLEEAVRKKGSEERRRPHKEEEEE 613
           +               +E V++K  E+ R   KE E+E
Sbjct: 266 EKIKE-----------KERVKEKDREKEREREKEREKE 292



 Score = 38.1 bits (87), Expect = 0.026
 Identities = 38/160 (23%), Positives = 59/160 (36%), Gaps = 17/160 (10%)

Query: 485 RARRPRARSVDALDDLTPPSTAESGSRSPTSNGGRSRAYMPPRSRSRDDLYDQDDSRDFP 544
           R  R R+ S D   D       +   +       R R     + + R    D+D  R+  
Sbjct: 249 RKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKEREKEKERGKNKDRDKEREKD 308

Query: 545 RSRDPHYDDFRSRERPPADPRSHHHRTRDPRDNGSRSGDLPYDGRLLEEAVRKKGSEERR 604
           R +D   D  R RE+        H + RD      +  +   D     E  R K  +E+R
Sbjct: 309 REKDKEKDREREREK-------EHEKDRD------KEKEKEQDKEKEREKDRSKEIDEKR 355

Query: 605 RPHKEEEEEAYYPPAPPPYSETDSQASRERRLKKNLALSR 644
           +  K+       PP     S     +SRERR +++ + SR
Sbjct: 356 KKDKKSRT----PPRSYNASRRSRSSSRERRRRRSRSSSR 391


>gi|42518065 tight junction protein 2 (zona occludens 2) isoform 2
           [Homo sapiens]
          Length = 1043

 Score = 40.4 bits (93), Expect = 0.005
 Identities = 57/232 (24%), Positives = 83/232 (35%), Gaps = 34/232 (14%)

Query: 386 EVRSGYRIQASQQDDSMRVLYYMEKELANFDPSRPGPPSGRVERAMSEVTSLHEDDWRSR 445
           +V   + +Q  ++   +  +             +  PP  + +RA   +       +RS 
Sbjct: 95  DVLHSFAVQQLRKSGKVAAIVVKRPRKVQVAALQASPPLDQDDRAFEVMDEFDGRSFRSG 154

Query: 446 PSRGPALTPIRDEEWGGHSPRSPRGWDQEPAREQAGGGWRAR-------RPRARSVDALD 498
            S    L          H  RS R W+  P R +     R+R       R R RS++   
Sbjct: 155 YSERSRLN--------SHGGRS-RSWEDSPERGRPHERARSRERDLSRDRSRGRSLERGL 205

Query: 499 DLTPPSTAESGSRSPTSNGGRSRAYMPPRSRSRDDL----YDQDDSRDFPRSRDPHYDDF 554
           D     T +  SR  +   G    + P R R RD       DQD  R + R+ DP Y+  
Sbjct: 206 DQDHARTRDR-SRGRSLERGLDHDFGPSRDRDRDRSRGRSIDQDYERAYHRAYDPDYERA 264

Query: 555 RSRERPPADPRSHHHRTRDPRDNGSRSGDLPYDGRLLEEAVRKKGSEERRRP 606
            S E        H  R+R PR   SRS + P+         R    E R RP
Sbjct: 265 YSPEYRRG--ARHDARSRGPR---SRSREHPHS--------RSPSPEPRGRP 303


>gi|42518070 tight junction protein 2 (zona occludens 2) isoform 1
           [Homo sapiens]
          Length = 1190

 Score = 40.4 bits (93), Expect = 0.005
 Identities = 57/232 (24%), Positives = 83/232 (35%), Gaps = 34/232 (14%)

Query: 386 EVRSGYRIQASQQDDSMRVLYYMEKELANFDPSRPGPPSGRVERAMSEVTSLHEDDWRSR 445
           +V   + +Q  ++   +  +             +  PP  + +RA   +       +RS 
Sbjct: 95  DVLHSFAVQQLRKSGKVAAIVVKRPRKVQVAALQASPPLDQDDRAFEVMDEFDGRSFRSG 154

Query: 446 PSRGPALTPIRDEEWGGHSPRSPRGWDQEPAREQAGGGWRAR-------RPRARSVDALD 498
            S    L          H  RS R W+  P R +     R+R       R R RS++   
Sbjct: 155 YSERSRLN--------SHGGRS-RSWEDSPERGRPHERARSRERDLSRDRSRGRSLERGL 205

Query: 499 DLTPPSTAESGSRSPTSNGGRSRAYMPPRSRSRDDL----YDQDDSRDFPRSRDPHYDDF 554
           D     T +  SR  +   G    + P R R RD       DQD  R + R+ DP Y+  
Sbjct: 206 DQDHARTRDR-SRGRSLERGLDHDFGPSRDRDRDRSRGRSIDQDYERAYHRAYDPDYERA 264

Query: 555 RSRERPPADPRSHHHRTRDPRDNGSRSGDLPYDGRLLEEAVRKKGSEERRRP 606
            S E        H  R+R PR   SRS + P+         R    E R RP
Sbjct: 265 YSPEYRRG--ARHDARSRGPR---SRSREHPHS--------RSPSPEPRGRP 303


>gi|38146113 arginine/serine-rich coiled-coil 2 isoform b [Homo
           sapiens]
          Length = 375

 Score = 39.7 bits (91), Expect = 0.009
 Identities = 50/164 (30%), Positives = 67/164 (40%), Gaps = 47/164 (28%)

Query: 508 SGSRSPTSNGGRSRAYMPPRSRSRDDLYDQDDSRDFPRSRDPHYDDFRSRERPPADPRS- 566
           S  RS + +  R R +   RSRSR+    +  SR+  +SR       RSRER  +  RS 
Sbjct: 61  SRGRSHSRSRSRERRH---RSRSRERKKSRSRSRERKKSRS------RSRERKKSRSRSR 111

Query: 567 ---------------HHHRTRDPRDNGSRSGDLPYDGRLLEEAVRKKGSEERRRPHKEEE 611
                          H HRTR      SRS D            RKK  E+ RR  +   
Sbjct: 112 ERKRRIRSRSRSRSRHRHRTRSRSRTRSRSRD------------RKKRIEKPRRFSRSLS 159

Query: 612 EEAYYPPAPPPY----SETDSQASRERRLK--KNLALSRESLVV 649
                 P+PPP+    +  D+Q +  RRL+  K L   RE  +V
Sbjct: 160 R----TPSPPPFRGRNTAMDAQEALARRLERAKKLQEQREKEMV 199



 Score = 29.6 bits (65), Expect = 9.1
 Identities = 26/119 (21%), Positives = 49/119 (41%), Gaps = 3/119 (2%)

Query: 529 RSRDDLYDQDDSRDFPRSRDPHYDDFRSRERPPADPRSHHHRTRDPRDNGSRSGDLPYDG 588
           + R+ L   ++  D  + ++      RS  R  +  R H  R+R+ + + SRS +     
Sbjct: 38  KGRERLNSSENGEDRHKRKERKSSRGRSHSRSRSRERRHRSRSRERKKSRSRSRERKKSR 97

Query: 589 RLLEE--AVRKKGSEERRRPHKEEEEEAYYPPAPPPYSETDSQA-SRERRLKKNLALSR 644
               E    R +  E +RR        + +       S T S++  R++R++K    SR
Sbjct: 98  SRSRERKKSRSRSRERKRRIRSRSRSRSRHRHRTRSRSRTRSRSRDRKKRIEKPRRFSR 156


>gi|47271443 splicing factor, arginine/serine-rich 2 [Homo sapiens]
          Length = 221

 Score = 39.3 bits (90), Expect = 0.011
 Identities = 37/118 (31%), Positives = 45/118 (38%), Gaps = 20/118 (16%)

Query: 463 HSPRSPRGWDQEPAREQAGGGW--------RARRPRARSVDALDDLTPPSTAESGSRSPT 514
           HS R P      P R   GGG+        R RR R+RS       +    + S SRS T
Sbjct: 100 HSRRGP------PPRRYGGGGYGRRSRSPRRRRRSRSRSRSRSRSRSRSRYSRSKSRSRT 153

Query: 515 SNGGRSRAYMPPRSRSRDDLYDQDDSRDFPRSRDPHYDDFRSRERPPADPRSHHHRTR 572
            +  RS       S+SR     +  S    RSR       RSR  PP   R    R+R
Sbjct: 154 RSRSRST------SKSRSARRSKSKSSSVSRSRSRSRSRSRSRSPPPVSKRESKSRSR 205


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.134    0.428 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 30,684,158
Number of Sequences: 37866
Number of extensions: 1722455
Number of successful extensions: 12321
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 82
Number of HSP's successfully gapped in prelim test: 384
Number of HSP's that attempted gapping in prelim test: 10247
Number of HSP's gapped (non-prelim): 1826
length of query: 649
length of database: 18,247,518
effective HSP length: 109
effective length of query: 540
effective length of database: 14,120,124
effective search space: 7624866960
effective search space used: 7624866960
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.