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Search of human proteins with 45238858
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|45238858 WD repeat domain 44 protein [Homo sapiens]
(913 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|45238858 WD repeat domain 44 protein [Homo sapiens] 1832 0.0
gi|199559532 Abelson helper integration site 1 isoform b [Homo s... 92 2e-18
gi|199559490 Abelson helper integration site 1 isoform a [Homo s... 92 2e-18
gi|199559438 Abelson helper integration site 1 isoform a [Homo s... 92 2e-18
gi|31542701 Abelson helper integration site 1 isoform a [Homo sa... 92 2e-18
gi|16554629 WD repeat domain 5 [Homo sapiens] 87 7e-17
gi|16554627 WD repeat domain 5 [Homo sapiens] 87 7e-17
gi|239787760 WD repeat domain 51A isoform 2 [Homo sapiens] 76 2e-13
gi|239787754 WD repeat domain 51A isoform 1 [Homo sapiens] 76 2e-13
gi|115298668 WD repeat domain 57 (U5 snRNP specific) [Homo sapiens] 75 2e-13
gi|26665869 WD repeat domain 51B [Homo sapiens] 71 5e-12
gi|239787764 WD repeat domain 51A isoform 3 [Homo sapiens] 70 1e-11
gi|23199987 WD repeat domain 5B [Homo sapiens] 70 1e-11
gi|153791298 mitogen-activated protein kinase organizer 1 [Homo ... 64 8e-10
gi|14150114 mitogen-activated protein kinase organizer 1 [Homo s... 64 8e-10
gi|52485606 formin-like 2 [Homo sapiens] 63 1e-09
gi|41281564 WD repeat domain 37 [Homo sapiens] 62 2e-09
gi|53759148 retinoblastoma binding protein 5 [Homo sapiens] 62 3e-09
gi|19913371 transducin (beta)-like 1 X-linked receptor 1 [Homo s... 61 5e-09
gi|13376840 WD repeat domain 61 [Homo sapiens] 60 7e-09
gi|11055998 guanine nucleotide-binding protein, beta-4 subunit [... 59 2e-08
gi|4885105 chromatin assembly factor 1 subunit B [Homo sapiens] 59 2e-08
gi|213021190 transducin beta-like 1X isoform b [Homo sapiens] 59 2e-08
gi|213021188 transducin beta-like 1X isoform b [Homo sapiens] 59 2e-08
gi|213021186 transducin beta-like 1X isoform a [Homo sapiens] 59 2e-08
gi|5032159 transducin beta-like 1X isoform a [Homo sapiens] 59 2e-08
gi|7657381 PRP19/PSO4 pre-mRNA processing factor 19 homolog [Hom... 59 3e-08
gi|11321585 guanine nucleotide-binding protein, beta-1 subunit [... 58 4e-08
gi|70909324 sperm associated antigen 16 isoform 1 [Homo sapiens] 57 6e-08
gi|189571685 WD repeat, sterile alpha motif and U-box domain con... 57 6e-08
>gi|45238858 WD repeat domain 44 protein [Homo sapiens]
Length = 913
Score = 1832 bits (4746), Expect = 0.0
Identities = 913/913 (100%), Positives = 913/913 (100%)
Query: 1 MASESDTEEFYDAPEDVHLGGGYPVGSPGKVGLSTFKETENTAYKVGNESPVQELKQDVS 60
MASESDTEEFYDAPEDVHLGGGYPVGSPGKVGLSTFKETENTAYKVGNESPVQELKQDVS
Sbjct: 1 MASESDTEEFYDAPEDVHLGGGYPVGSPGKVGLSTFKETENTAYKVGNESPVQELKQDVS 60
Query: 61 KKIIESIIEESQKVLQLEDDSLDSKGKELSDQATASPIVARTDLSNIPGLLAIDQVLPEE 120
KKIIESIIEESQKVLQLEDDSLDSKGKELSDQATASPIVARTDLSNIPGLLAIDQVLPEE
Sbjct: 61 KKIIESIIEESQKVLQLEDDSLDSKGKELSDQATASPIVARTDLSNIPGLLAIDQVLPEE 120
Query: 121 SQKAESQNTFEETELELKKCFPSDETCEKPVDETTKLTQTSSTEQLNVLETETEVLNKEA 180
SQKAESQNTFEETELELKKCFPSDETCEKPVDETTKLTQTSSTEQLNVLETETEVLNKEA
Sbjct: 121 SQKAESQNTFEETELELKKCFPSDETCEKPVDETTKLTQTSSTEQLNVLETETEVLNKEA 180
Query: 181 VEVKGGGDVLEPVSSDSLSTKDFAAVEEVAPAKPPRHLTPEPDIVASTKKPVPARPPPPT 240
VEVKGGGDVLEPVSSDSLSTKDFAAVEEVAPAKPPRHLTPEPDIVASTKKPVPARPPPPT
Sbjct: 181 VEVKGGGDVLEPVSSDSLSTKDFAAVEEVAPAKPPRHLTPEPDIVASTKKPVPARPPPPT 240
Query: 241 NFPPPRPPPPSRPAPPPRKRKSELEFETLKTPDIDVPKENITSDSLLTASMASESTVKDS 300
NFPPPRPPPPSRPAPPPRKRKSELEFETLKTPDIDVPKENITSDSLLTASMASESTVKDS
Sbjct: 241 NFPPPRPPPPSRPAPPPRKRKSELEFETLKTPDIDVPKENITSDSLLTASMASESTVKDS 300
Query: 301 QPSLDLASATSGDKIVTAQENGKAPDGQTVAGEVMGPQRPRSNSGRELTDEEILASVMIK 360
QPSLDLASATSGDKIVTAQENGKAPDGQTVAGEVMGPQRPRSNSGRELTDEEILASVMIK
Sbjct: 301 QPSLDLASATSGDKIVTAQENGKAPDGQTVAGEVMGPQRPRSNSGRELTDEEILASVMIK 360
Query: 361 NLDTGEEIPLSLAEEKLPTGINPLTLHIMRRTKEYVSNDAAQSDDEEKLQSQPTDTDGGR 420
NLDTGEEIPLSLAEEKLPTGINPLTLHIMRRTKEYVSNDAAQSDDEEKLQSQPTDTDGGR
Sbjct: 361 NLDTGEEIPLSLAEEKLPTGINPLTLHIMRRTKEYVSNDAAQSDDEEKLQSQPTDTDGGR 420
Query: 421 LKQKTTQLKKFLGKSVKRAKHLAEEYGERAINKVKSVRDEVFHTDQDDPSSSDDEGMPYT 480
LKQKTTQLKKFLGKSVKRAKHLAEEYGERAINKVKSVRDEVFHTDQDDPSSSDDEGMPYT
Sbjct: 421 LKQKTTQLKKFLGKSVKRAKHLAEEYGERAINKVKSVRDEVFHTDQDDPSSSDDEGMPYT 480
Query: 481 RPVKFKAAHGFKGPYDFDQIKVVQDLSGEHMGAVWTMKFSHCGRLLASAGQDNVVRIWAL 540
RPVKFKAAHGFKGPYDFDQIKVVQDLSGEHMGAVWTMKFSHCGRLLASAGQDNVVRIWAL
Sbjct: 481 RPVKFKAAHGFKGPYDFDQIKVVQDLSGEHMGAVWTMKFSHCGRLLASAGQDNVVRIWAL 540
Query: 541 KNAFDYFNNMRMKYNTEGRVSPSPSQESLSSSKSDTDTGVCSGTDEDPDDKNAPFRQRPF 600
KNAFDYFNNMRMKYNTEGRVSPSPSQESLSSSKSDTDTGVCSGTDEDPDDKNAPFRQRPF
Sbjct: 541 KNAFDYFNNMRMKYNTEGRVSPSPSQESLSSSKSDTDTGVCSGTDEDPDDKNAPFRQRPF 600
Query: 601 CKYKGHTADLLDLSWSKNYFLLSSSMDKTVRLWHISRRECLCCFQHIDFVTAIAFHPRDD 660
CKYKGHTADLLDLSWSKNYFLLSSSMDKTVRLWHISRRECLCCFQHIDFVTAIAFHPRDD
Sbjct: 601 CKYKGHTADLLDLSWSKNYFLLSSSMDKTVRLWHISRRECLCCFQHIDFVTAIAFHPRDD 660
Query: 661 RYFLSGSLDGKLRLWNIPDKKVALWNEVDGQTKLITAANFCQNGKYAVIGTYDGRCIFYD 720
RYFLSGSLDGKLRLWNIPDKKVALWNEVDGQTKLITAANFCQNGKYAVIGTYDGRCIFYD
Sbjct: 661 RYFLSGSLDGKLRLWNIPDKKVALWNEVDGQTKLITAANFCQNGKYAVIGTYDGRCIFYD 720
Query: 721 TEHLKYHTQIHVRSTRGRNKVGRKITGIEPLPGENKILVTSNDSRIRLYDLRDLSLSMKY 780
TEHLKYHTQIHVRSTRGRNKVGRKITGIEPLPGENKILVTSNDSRIRLYDLRDLSLSMKY
Sbjct: 721 TEHLKYHTQIHVRSTRGRNKVGRKITGIEPLPGENKILVTSNDSRIRLYDLRDLSLSMKY 780
Query: 781 KGYVNSSSQIKASFSHDFTYLVSGSEDKYVYIWSTYHDLSKFTSVRRDRNDFWEGIKAHN 840
KGYVNSSSQIKASFSHDFTYLVSGSEDKYVYIWSTYHDLSKFTSVRRDRNDFWEGIKAHN
Sbjct: 781 KGYVNSSSQIKASFSHDFTYLVSGSEDKYVYIWSTYHDLSKFTSVRRDRNDFWEGIKAHN 840
Query: 841 AVVTSAIFAPNPSLMLSLDVQSEKSEGNEKSEDAEVLDATPSGIMKTDNTEVLLSADFTG 900
AVVTSAIFAPNPSLMLSLDVQSEKSEGNEKSEDAEVLDATPSGIMKTDNTEVLLSADFTG
Sbjct: 841 AVVTSAIFAPNPSLMLSLDVQSEKSEGNEKSEDAEVLDATPSGIMKTDNTEVLLSADFTG 900
Query: 901 AIKVFVNKRKNVS 913
AIKVFVNKRKNVS
Sbjct: 901 AIKVFVNKRKNVS 913
>gi|199559532 Abelson helper integration site 1 isoform b [Homo
sapiens]
Length = 1053
Score = 92.0 bits (227), Expect = 2e-18
Identities = 64/222 (28%), Positives = 105/222 (47%), Gaps = 14/222 (6%)
Query: 605 GHTADLLDLSWSKN-YFLLSSSMDKTVRLW--HISRRECLCCFQHIDFVTAIAFHPRDDR 661
GH + DLSWSK+ +++L+SS D T R+W I+ H FV FHP
Sbjct: 652 GHLNIIYDLSWSKDDHYILTSSSDGTARIWKNEINNTNTFRVLPHPSFVYTAKFHPAVRE 711
Query: 662 YFLSGSLDGKLRLWNIP--DKKVALWNEVDGQTKLITAANFCQNGKYAVIGTYDGRCIFY 719
++G D +R+W + + L + D I + F G + G G + +
Sbjct: 712 LVVTGCYDSMIRIWKVEMREDSAILVRQFDVHKSFINSLCFDTEGHHMYSGDCTGVIVVW 771
Query: 720 DT-------EHLKYHTQIHVRSTRGRNKVGRKITGIEPLPGENKILVTSNDSRIRLYDLR 772
+T EH +H I+ K G I+ +E P ++L+ + DS +R+ DLR
Sbjct: 772 NTYVKINDLEHSVHHWTINKEIKETEFK-GIPISYLEIHPNGKRLLIHTKDSTLRIMDLR 830
Query: 773 DLSLSMKYKGYVNSSSQIKASFSHDFTYLVSGSEDKYVYIWS 814
L ++ K+ G N +I ++ + T+L +GSED VY+W+
Sbjct: 831 IL-VARKFVGAANYREKIHSTLTPCGTFLFAGSEDGIVYVWN 871
>gi|199559490 Abelson helper integration site 1 isoform a [Homo
sapiens]
Length = 1196
Score = 92.0 bits (227), Expect = 2e-18
Identities = 64/222 (28%), Positives = 105/222 (47%), Gaps = 14/222 (6%)
Query: 605 GHTADLLDLSWSKN-YFLLSSSMDKTVRLW--HISRRECLCCFQHIDFVTAIAFHPRDDR 661
GH + DLSWSK+ +++L+SS D T R+W I+ H FV FHP
Sbjct: 652 GHLNIIYDLSWSKDDHYILTSSSDGTARIWKNEINNTNTFRVLPHPSFVYTAKFHPAVRE 711
Query: 662 YFLSGSLDGKLRLWNIP--DKKVALWNEVDGQTKLITAANFCQNGKYAVIGTYDGRCIFY 719
++G D +R+W + + L + D I + F G + G G + +
Sbjct: 712 LVVTGCYDSMIRIWKVEMREDSAILVRQFDVHKSFINSLCFDTEGHHMYSGDCTGVIVVW 771
Query: 720 DT-------EHLKYHTQIHVRSTRGRNKVGRKITGIEPLPGENKILVTSNDSRIRLYDLR 772
+T EH +H I+ K G I+ +E P ++L+ + DS +R+ DLR
Sbjct: 772 NTYVKINDLEHSVHHWTINKEIKETEFK-GIPISYLEIHPNGKRLLIHTKDSTLRIMDLR 830
Query: 773 DLSLSMKYKGYVNSSSQIKASFSHDFTYLVSGSEDKYVYIWS 814
L ++ K+ G N +I ++ + T+L +GSED VY+W+
Sbjct: 831 IL-VARKFVGAANYREKIHSTLTPCGTFLFAGSEDGIVYVWN 871
>gi|199559438 Abelson helper integration site 1 isoform a [Homo
sapiens]
Length = 1196
Score = 92.0 bits (227), Expect = 2e-18
Identities = 64/222 (28%), Positives = 105/222 (47%), Gaps = 14/222 (6%)
Query: 605 GHTADLLDLSWSKN-YFLLSSSMDKTVRLW--HISRRECLCCFQHIDFVTAIAFHPRDDR 661
GH + DLSWSK+ +++L+SS D T R+W I+ H FV FHP
Sbjct: 652 GHLNIIYDLSWSKDDHYILTSSSDGTARIWKNEINNTNTFRVLPHPSFVYTAKFHPAVRE 711
Query: 662 YFLSGSLDGKLRLWNIP--DKKVALWNEVDGQTKLITAANFCQNGKYAVIGTYDGRCIFY 719
++G D +R+W + + L + D I + F G + G G + +
Sbjct: 712 LVVTGCYDSMIRIWKVEMREDSAILVRQFDVHKSFINSLCFDTEGHHMYSGDCTGVIVVW 771
Query: 720 DT-------EHLKYHTQIHVRSTRGRNKVGRKITGIEPLPGENKILVTSNDSRIRLYDLR 772
+T EH +H I+ K G I+ +E P ++L+ + DS +R+ DLR
Sbjct: 772 NTYVKINDLEHSVHHWTINKEIKETEFK-GIPISYLEIHPNGKRLLIHTKDSTLRIMDLR 830
Query: 773 DLSLSMKYKGYVNSSSQIKASFSHDFTYLVSGSEDKYVYIWS 814
L ++ K+ G N +I ++ + T+L +GSED VY+W+
Sbjct: 831 IL-VARKFVGAANYREKIHSTLTPCGTFLFAGSEDGIVYVWN 871
>gi|31542701 Abelson helper integration site 1 isoform a [Homo
sapiens]
Length = 1196
Score = 92.0 bits (227), Expect = 2e-18
Identities = 64/222 (28%), Positives = 105/222 (47%), Gaps = 14/222 (6%)
Query: 605 GHTADLLDLSWSKN-YFLLSSSMDKTVRLW--HISRRECLCCFQHIDFVTAIAFHPRDDR 661
GH + DLSWSK+ +++L+SS D T R+W I+ H FV FHP
Sbjct: 652 GHLNIIYDLSWSKDDHYILTSSSDGTARIWKNEINNTNTFRVLPHPSFVYTAKFHPAVRE 711
Query: 662 YFLSGSLDGKLRLWNIP--DKKVALWNEVDGQTKLITAANFCQNGKYAVIGTYDGRCIFY 719
++G D +R+W + + L + D I + F G + G G + +
Sbjct: 712 LVVTGCYDSMIRIWKVEMREDSAILVRQFDVHKSFINSLCFDTEGHHMYSGDCTGVIVVW 771
Query: 720 DT-------EHLKYHTQIHVRSTRGRNKVGRKITGIEPLPGENKILVTSNDSRIRLYDLR 772
+T EH +H I+ K G I+ +E P ++L+ + DS +R+ DLR
Sbjct: 772 NTYVKINDLEHSVHHWTINKEIKETEFK-GIPISYLEIHPNGKRLLIHTKDSTLRIMDLR 830
Query: 773 DLSLSMKYKGYVNSSSQIKASFSHDFTYLVSGSEDKYVYIWS 814
L ++ K+ G N +I ++ + T+L +GSED VY+W+
Sbjct: 831 IL-VARKFVGAANYREKIHSTLTPCGTFLFAGSEDGIVYVWN 871
>gi|16554629 WD repeat domain 5 [Homo sapiens]
Length = 334
Score = 87.0 bits (214), Expect = 7e-17
Identities = 96/403 (23%), Positives = 166/403 (41%), Gaps = 95/403 (23%)
Query: 466 QDDPSSSDDEGMPYTRPVKFKAAHGFKGPYDFDQIKVVQDLSGEHMGAVWTMKFSHCGRL 525
Q PSSS + P PVK A F L+G H AV ++KFS G
Sbjct: 16 QPTPSSSATQSKP--TPVKPNYALKFT-------------LAG-HTKAVSSVKFSPNGEW 59
Query: 526 LASAGQDNVVRIWALKNAFDYFNNMRMKYNTEGRVSPSPSQESLSSSKSDTDTGVCSGTD 585
LAS+ D +++IW A+D G+ + S L S
Sbjct: 60 LASSSADKLIKIW---GAYD------------GKFEKTISGHKLGIS------------- 91
Query: 586 EDPDDKNAPFRQRPFCKYKGHTADLLDLSWSK-NYFLLSSSMDKTVRLWHISRRECLCCF 644
D++WS + L+S+S DKT+++W +S +CL
Sbjct: 92 --------------------------DVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTL 125
Query: 645 Q-HIDFVTAIAFHPRDDRYFLSGSLDGKLRLWNIPDKKVALWNEVDGQTKLITAANFCQN 703
+ H ++V F+P+ + +SGS D +R+W++ K + + ++A +F ++
Sbjct: 126 KGHSNYVFCCNFNPQSN-LIVSGSFDESVRIWDVKTGKCL--KTLPAHSDPVSAVHFNRD 182
Query: 704 GKYAVIGTYDGRCIFYDTEHLKYHTQIHVRSTRGRNKVGRKITGIEPLPGENKILVTSND 763
G V +YDG C +DT + + + ++ ++ P IL + D
Sbjct: 183 GSLIVSSSYDGLCRIWDTASGQCLKTL-------IDDDNPPVSFVKFSPNGKYILAATLD 235
Query: 764 SRIRLYDLRDLSLSMKYKGYVNSSSQIKASFS-HDFTYLVSGSEDKYVYIWSTYHDLSKF 822
+ ++L+D Y G+ N I A+FS ++VSGSED VYIW+
Sbjct: 236 NTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNL------- 288
Query: 823 TSVRRDRNDFWEGIKAHNAVVTSAIFAPNPSLMLSLDVQSEKS 865
+ + ++ H VV S P +++ S ++++K+
Sbjct: 289 -----QTKEIVQKLQGHTDVVISTACHPTENIIASAALENDKT 326
>gi|16554627 WD repeat domain 5 [Homo sapiens]
Length = 334
Score = 87.0 bits (214), Expect = 7e-17
Identities = 96/403 (23%), Positives = 166/403 (41%), Gaps = 95/403 (23%)
Query: 466 QDDPSSSDDEGMPYTRPVKFKAAHGFKGPYDFDQIKVVQDLSGEHMGAVWTMKFSHCGRL 525
Q PSSS + P PVK A F L+G H AV ++KFS G
Sbjct: 16 QPTPSSSATQSKP--TPVKPNYALKFT-------------LAG-HTKAVSSVKFSPNGEW 59
Query: 526 LASAGQDNVVRIWALKNAFDYFNNMRMKYNTEGRVSPSPSQESLSSSKSDTDTGVCSGTD 585
LAS+ D +++IW A+D G+ + S L S
Sbjct: 60 LASSSADKLIKIW---GAYD------------GKFEKTISGHKLGIS------------- 91
Query: 586 EDPDDKNAPFRQRPFCKYKGHTADLLDLSWSK-NYFLLSSSMDKTVRLWHISRRECLCCF 644
D++WS + L+S+S DKT+++W +S +CL
Sbjct: 92 --------------------------DVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTL 125
Query: 645 Q-HIDFVTAIAFHPRDDRYFLSGSLDGKLRLWNIPDKKVALWNEVDGQTKLITAANFCQN 703
+ H ++V F+P+ + +SGS D +R+W++ K + + ++A +F ++
Sbjct: 126 KGHSNYVFCCNFNPQSN-LIVSGSFDESVRIWDVKTGKCL--KTLPAHSDPVSAVHFNRD 182
Query: 704 GKYAVIGTYDGRCIFYDTEHLKYHTQIHVRSTRGRNKVGRKITGIEPLPGENKILVTSND 763
G V +YDG C +DT + + + ++ ++ P IL + D
Sbjct: 183 GSLIVSSSYDGLCRIWDTASGQCLKTL-------IDDDNPPVSFVKFSPNGKYILAATLD 235
Query: 764 SRIRLYDLRDLSLSMKYKGYVNSSSQIKASFS-HDFTYLVSGSEDKYVYIWSTYHDLSKF 822
+ ++L+D Y G+ N I A+FS ++VSGSED VYIW+
Sbjct: 236 NTLKLWDYSKGKCLKTYTGHKNEKYCIFANFSVTGGKWIVSGSEDNLVYIWNL------- 288
Query: 823 TSVRRDRNDFWEGIKAHNAVVTSAIFAPNPSLMLSLDVQSEKS 865
+ + ++ H VV S P +++ S ++++K+
Sbjct: 289 -----QTKEIVQKLQGHTDVVISTACHPTENIIASAALENDKT 326
>gi|239787760 WD repeat domain 51A isoform 2 [Homo sapiens]
Length = 359
Score = 75.9 bits (185), Expect = 2e-13
Identities = 77/315 (24%), Positives = 134/315 (42%), Gaps = 33/315 (10%)
Query: 510 HMGAVWTMKFSHCGRLLASAGQDNVVRIWALKNAFDYFNNMRMKYNTEGRVSPSPSQESL 569
H AV + FS + LAS D+ + +W +K + K + V+ SPS L
Sbjct: 18 HRDAVTCVDFSINTKQLASGSMDSCLMVWHMKPQSRAYRFTGHK-DAVTCVNFSPSGHLL 76
Query: 570 SSSKSDTDTGVCSGTDEDPDDKNAPFRQRPFCKYKGHTADLLDLSW-SKNYFLLSSSMDK 628
+S D + P + ++ HTA + + + S +++S DK
Sbjct: 77 ASGSRDKTVRIW-----------VPNVKGESTVFRAHTATVRSVHFCSDGQSFVTASDDK 125
Query: 629 TVRLWHISRRECLCCF-QHIDFVTAIAFHPRDDRYFLSGSLDGKLRLWNIPDKK-VALWN 686
TV++W R++ L QHI++V F P D R +S S D ++LW+ ++ V +
Sbjct: 126 TVKVWATHRQKFLFSLSQHINWVRCAKFSP-DGRLIVSASDDKTVKLWDKSSRECVHSYC 184
Query: 687 EVDGQTKLITAANFCQNGKYAVIGTYDGRCIFYD--TEHLKYHTQIHVRSTRGRNKVGRK 744
E G +T +F +G D +D T L H Q+H +
Sbjct: 185 EHGG---FVTYVDFHPSGTCIAAAGMDNTVKVWDVRTHRLLQHYQLHSAA---------- 231
Query: 745 ITGIEPLPGENKILVTSNDSRIRLYDLRDLSLSMKYKGYVNSSSQIKASFSHDFTYLVSG 804
+ G+ P N ++ S+DS +++ DL + L G+ ++ + +FS Y SG
Sbjct: 232 VNGLSFHPSGNYLITASSDSTLKILDLMEGRLLYTLHGHQGPATTV--AFSRTGEYFASG 289
Query: 805 SEDKYVYIWSTYHDL 819
D+ V +W + D+
Sbjct: 290 GSDEQVMVWKSNFDI 304
Score = 40.0 bits (92), Expect = 0.010
Identities = 58/224 (25%), Positives = 92/224 (41%), Gaps = 34/224 (15%)
Query: 456 SVRDEVFHTD-QDDPSSSDDEGMPYTRPVKFKAAHGFKGPYDFDQIKVVQDLSGEHMGAV 514
+VR F +D Q ++SDD + VK A H K + Q H+ V
Sbjct: 105 TVRSVHFCSDGQSFVTASDD------KTVKVWATHRQKFLFSLSQ----------HINWV 148
Query: 515 WTMKFSHCGRLLASAGQDNVVRIWALKNAFDYFNNMRMKYNTEGRVSPSPSQESLSSSKS 574
KFS GRL+ SA D V++W K++ + ++ V PS ++++
Sbjct: 149 RCAKFSPDGRLIVSASDDKTVKLWD-KSSRECVHSYCEHGGFVTYVDFHPSGTCIAAAGM 207
Query: 575 DTDTGVCSGTDEDPDDKNAPFRQRPFCKYKGHTADLLDLSW--SKNYFLLSSSMDKTVRL 632
D V R Y+ H+A + LS+ S NY L+++S D T+++
Sbjct: 208 DNTVKVWDVR-----------THRLLQHYQLHSAAVNGLSFHPSGNY-LITASSDSTLKI 255
Query: 633 WHISRRECLCCFQ-HIDFVTAIAFHPRDDRYFLSGSLDGKLRLW 675
+ L H T +AF R YF SG D ++ +W
Sbjct: 256 LDLMEGRLLYTLHGHQGPATTVAF-SRTGEYFASGGSDEQVMVW 298
Score = 31.2 bits (69), Expect = 4.6
Identities = 36/168 (21%), Positives = 68/168 (40%), Gaps = 22/168 (13%)
Query: 690 GQTKLITAANFCQNGKYAVIGTYDGRCIFYDTEHLKYHTQIHVRSTRGRNKVGRKITGIE 749
G +T +F N K G+ D + + H+K ++ + R T ++ V T +
Sbjct: 17 GHRDAVTCVDFSINTKQLASGSMDSCLMVW---HMKPQSRAY-RFTGHKDAV----TCVN 68
Query: 750 PLPGENKILVTSNDSRIRLYDLRDLSLSMKYKGYVNSSSQIKASFSHDFTYLVSGSEDKY 809
P + + S D +R++ S ++ + + + F D V+ S+DK
Sbjct: 69 FSPSGHLLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVH--FCSDGQSFVTASDDKT 126
Query: 810 VYIWSTYHDLSKFTSVRRDRNDFWEGIKAHNAVVTSAIFAPNPSLMLS 857
V +W+T+ R F + H V A F+P+ L++S
Sbjct: 127 VKVWATH------------RQKFLFSLSQHINWVRCAKFSPDGRLIVS 162
>gi|239787754 WD repeat domain 51A isoform 1 [Homo sapiens]
Length = 407
Score = 75.9 bits (185), Expect = 2e-13
Identities = 77/315 (24%), Positives = 134/315 (42%), Gaps = 33/315 (10%)
Query: 510 HMGAVWTMKFSHCGRLLASAGQDNVVRIWALKNAFDYFNNMRMKYNTEGRVSPSPSQESL 569
H AV + FS + LAS D+ + +W +K + K + V+ SPS L
Sbjct: 18 HRDAVTCVDFSINTKQLASGSMDSCLMVWHMKPQSRAYRFTGHK-DAVTCVNFSPSGHLL 76
Query: 570 SSSKSDTDTGVCSGTDEDPDDKNAPFRQRPFCKYKGHTADLLDLSW-SKNYFLLSSSMDK 628
+S D + P + ++ HTA + + + S +++S DK
Sbjct: 77 ASGSRDKTVRIW-----------VPNVKGESTVFRAHTATVRSVHFCSDGQSFVTASDDK 125
Query: 629 TVRLWHISRRECLCCF-QHIDFVTAIAFHPRDDRYFLSGSLDGKLRLWNIPDKK-VALWN 686
TV++W R++ L QHI++V F P D R +S S D ++LW+ ++ V +
Sbjct: 126 TVKVWATHRQKFLFSLSQHINWVRCAKFSP-DGRLIVSASDDKTVKLWDKSSRECVHSYC 184
Query: 687 EVDGQTKLITAANFCQNGKYAVIGTYDGRCIFYD--TEHLKYHTQIHVRSTRGRNKVGRK 744
E G +T +F +G D +D T L H Q+H +
Sbjct: 185 EHGG---FVTYVDFHPSGTCIAAAGMDNTVKVWDVRTHRLLQHYQLHSAA---------- 231
Query: 745 ITGIEPLPGENKILVTSNDSRIRLYDLRDLSLSMKYKGYVNSSSQIKASFSHDFTYLVSG 804
+ G+ P N ++ S+DS +++ DL + L G+ ++ + +FS Y SG
Sbjct: 232 VNGLSFHPSGNYLITASSDSTLKILDLMEGRLLYTLHGHQGPATTV--AFSRTGEYFASG 289
Query: 805 SEDKYVYIWSTYHDL 819
D+ V +W + D+
Sbjct: 290 GSDEQVMVWKSNFDI 304
Score = 40.0 bits (92), Expect = 0.010
Identities = 58/224 (25%), Positives = 92/224 (41%), Gaps = 34/224 (15%)
Query: 456 SVRDEVFHTD-QDDPSSSDDEGMPYTRPVKFKAAHGFKGPYDFDQIKVVQDLSGEHMGAV 514
+VR F +D Q ++SDD + VK A H K + Q H+ V
Sbjct: 105 TVRSVHFCSDGQSFVTASDD------KTVKVWATHRQKFLFSLSQ----------HINWV 148
Query: 515 WTMKFSHCGRLLASAGQDNVVRIWALKNAFDYFNNMRMKYNTEGRVSPSPSQESLSSSKS 574
KFS GRL+ SA D V++W K++ + ++ V PS ++++
Sbjct: 149 RCAKFSPDGRLIVSASDDKTVKLWD-KSSRECVHSYCEHGGFVTYVDFHPSGTCIAAAGM 207
Query: 575 DTDTGVCSGTDEDPDDKNAPFRQRPFCKYKGHTADLLDLSW--SKNYFLLSSSMDKTVRL 632
D V R Y+ H+A + LS+ S NY L+++S D T+++
Sbjct: 208 DNTVKVWDVR-----------THRLLQHYQLHSAAVNGLSFHPSGNY-LITASSDSTLKI 255
Query: 633 WHISRRECLCCFQ-HIDFVTAIAFHPRDDRYFLSGSLDGKLRLW 675
+ L H T +AF R YF SG D ++ +W
Sbjct: 256 LDLMEGRLLYTLHGHQGPATTVAF-SRTGEYFASGGSDEQVMVW 298
Score = 31.2 bits (69), Expect = 4.6
Identities = 36/168 (21%), Positives = 68/168 (40%), Gaps = 22/168 (13%)
Query: 690 GQTKLITAANFCQNGKYAVIGTYDGRCIFYDTEHLKYHTQIHVRSTRGRNKVGRKITGIE 749
G +T +F N K G+ D + + H+K ++ + R T ++ V T +
Sbjct: 17 GHRDAVTCVDFSINTKQLASGSMDSCLMVW---HMKPQSRAY-RFTGHKDAV----TCVN 68
Query: 750 PLPGENKILVTSNDSRIRLYDLRDLSLSMKYKGYVNSSSQIKASFSHDFTYLVSGSEDKY 809
P + + S D +R++ S ++ + + + F D V+ S+DK
Sbjct: 69 FSPSGHLLASGSRDKTVRIWVPNVKGESTVFRAHTATVRSVH--FCSDGQSFVTASDDKT 126
Query: 810 VYIWSTYHDLSKFTSVRRDRNDFWEGIKAHNAVVTSAIFAPNPSLMLS 857
V +W+T+ R F + H V A F+P+ L++S
Sbjct: 127 VKVWATH------------RQKFLFSLSQHINWVRCAKFSPDGRLIVS 162
>gi|115298668 WD repeat domain 57 (U5 snRNP specific) [Homo sapiens]
Length = 357
Score = 75.5 bits (184), Expect = 2e-13
Identities = 74/318 (23%), Positives = 135/318 (42%), Gaps = 37/318 (11%)
Query: 506 LSGEHMGAVWTMKFSHCGRLLASAGQDNVVRIWALKNAFDYFNN--------MRMKYNTE 557
LSG H G V+ KF G LASAG D ++ +W + D + M + YNT+
Sbjct: 62 LSG-HEGEVYCCKFHPNGSTLASAGFDRLILLWNVYGDCDNYATLKGHSGAVMELHYNTD 120
Query: 558 GRVSPSPSQESLSSSKSDTDTGVCSGTDEDPDDKNAPFRQRPFCKYKGHTADLLDLSWSK 617
G + S S + + + D++TG + KGHT+ + ++
Sbjct: 121 GSMLFSASTDK-TVAVWDSETG------------------ERVKRLKGHTSFVNSCYPAR 161
Query: 618 N--YFLLSSSMDKTVRLWHISRRECLCCFQHIDFVTAIAFHPRDDRYFLSGSLDGKLRLW 675
+ + S D TV+LW I ++ + FQ+ V A+ F+ D+ +SG +D +++W
Sbjct: 162 RGPQLVCTGSDDGTVKLWDIRKKAAIQTFQNTYQVLAVTFNDTSDQ-IISGGIDNDIKVW 220
Query: 676 NIPDKKVALWNEVDGQTKLITAANFCQNGKYAVIGTYDGRCIFYDTEHLKYHTQIHVRST 735
++ K L + G +T + G Y + D +D + V+
Sbjct: 221 DLRQNK--LTYTMRGHADSVTGLSLSSEGSYLLSNAMDNTVRVWDVRPFAPKERC-VKIF 277
Query: 736 RGR-NKVGRKITGIEPLPGENKILVTSNDSRIRLYDLRDLSLSMKYKGYVNSSSQIKASF 794
+G + + + P +KI S D + ++D + K G+ S +++ +F
Sbjct: 278 QGNVHNFEKNLLRCSWSPDGSKIAAGSADRFVYVWDTTSRRILYKLPGHAGSINEV--AF 335
Query: 795 SHDFTYLVSGSEDKYVYI 812
D ++S S DK +Y+
Sbjct: 336 HPDEPIIISASSDKRLYM 353
Score = 64.7 bits (156), Expect = 4e-10
Identities = 56/226 (24%), Positives = 106/226 (46%), Gaps = 23/226 (10%)
Query: 600 FCKYKGHTADLLDLSWSKN-YFLLSSSMDKTVRLWHISRRECLCCFQ-HIDFVTAIAFHP 657
+ KGH+ +++L ++ + L S+S DKTV +W E + + H FV +
Sbjct: 102 YATLKGHSGAVMELHYNTDGSMLFSASTDKTVAVWDSETGERVKRLKGHTSFVNSCYPAR 161
Query: 658 RDDRYFLSGSLDGKLRLWNIPDKKVALWNEVDGQTKLITAANFCQNGKYAVIGTYDGRCI 717
R + +GS DG ++LW+I KK A+ + T + A F + G D
Sbjct: 162 RGPQLVCTGSDDGTVKLWDIR-KKAAI--QTFQNTYQVLAVTFNDTSDQIISGGIDNDIK 218
Query: 718 FYDTEH--LKYHTQIHVRSTRGRNKVGRKITGIEPLPGENKILVTSNDSRIRLYDLRDLS 775
+D L Y + H S +TG+ + +L + D+ +R++D+R +
Sbjct: 219 VWDLRQNKLTYTMRGHADS----------VTGLSLSSEGSYLLSNAMDNTVRVWDVRPFA 268
Query: 776 LSMK----YKGYVNSSSQ--IKASFSHDFTYLVSGSEDKYVYIWST 815
+ ++G V++ + ++ S+S D + + +GS D++VY+W T
Sbjct: 269 PKERCVKIFQGNVHNFEKNLLRCSWSPDGSKIAAGSADRFVYVWDT 314
>gi|26665869 WD repeat domain 51B [Homo sapiens]
Length = 478
Score = 70.9 bits (172), Expect = 5e-12
Identities = 72/316 (22%), Positives = 128/316 (40%), Gaps = 37/316 (11%)
Query: 510 HMGAVWTMKFSHCGRLLASAGQDNVVRIWALK---NAFDYFNNMRMKYNTEGRVSPSPSQ 566
H A+ ++ S G+ LA+A D + +W K A+ Y + + + V SP
Sbjct: 17 HKAAITSLDLSPNGKQLATASWDTFLMLWNFKPHARAYRYVGHKDVVTS----VQFSPHG 72
Query: 567 ESLSSSKSDTDTGVCSGTDEDPDDKNAPFRQRPFCKYKGHTADLLDLSWSKN-YFLLSSS 625
L+S+ D + P ++ F ++K HTA + + +S + FL ++S
Sbjct: 73 NLLASASRDRTVRLW-----------IPDKRGKFSEFKAHTAPVRSVDFSADGQFLATAS 121
Query: 626 MDKTVRLWHISRRECL-CCFQHIDFVTAIAFHPRDDRYFLSGSLDGKLRLWNIPDKKVAL 684
DK++++W + R+ L ++H +V F P D R +S S D +++W+ +K+
Sbjct: 122 EDKSIKVWSMYRQRFLYSLYRHTHWVRCAKFSP-DGRLIVSCSEDKTIKIWDTTNKQCV- 179
Query: 685 WNEVDGQTKLITAANFCQNGKYAVIGTYDGRCIFYDTE--HLKYHTQIHVRSTRGRNKVG 742
N +F +G D +D L H Q+H
Sbjct: 180 -NNFSDSVGFANFVDFNPSGTCIASAGSDQTVKVWDVRVNKLLQHYQVHSGG-------- 230
Query: 743 RKITGIEPLPGENKILVTSNDSRIRLYDLRDLSLSMKYKGYVNSSSQIKASFSHDFTYLV 802
+ I P N ++ S+D +++ DL + L +G+ + SFS
Sbjct: 231 --VNCISFHPSGNYLITASSDGTLKILDLLEGRLIYTLQGHTGPVFTV--SFSKGGELFA 286
Query: 803 SGSEDKYVYIWSTYHD 818
SG D V +W T D
Sbjct: 287 SGGADTQVLLWRTNFD 302
Score = 43.5 bits (101), Expect = 9e-04
Identities = 42/170 (24%), Positives = 70/170 (41%), Gaps = 26/170 (15%)
Query: 690 GQTKLITAANFCQNGKYAVIGTYDGRCIFYDTEHLKYHTQIHVRSTRGRNKVGRK--ITG 747
G IT+ + NGK ++D T + ++ + H R+ R VG K +T
Sbjct: 16 GHKAAITSLDLSPNGKQLATASWD-------TFLMLWNFKPHARAYR---YVGHKDVVTS 65
Query: 748 IEPLPGENKILVTSNDSRIRLYDLRDLSLSMKYKGYVNSSSQIKASFSHDFTYLVSGSED 807
++ P N + S D +RL+ ++K + + FS D +L + SED
Sbjct: 66 VQFSPHGNLLASASRDRTVRLWIPDKRGKFSEFKAHTAPVRSV--DFSADGQFLATASED 123
Query: 808 KYVYIWSTYHDLSKFTSVRRDRNDFWEGIKAHNAVVTSAIFAPNPSLMLS 857
K + +WS Y R F + H V A F+P+ L++S
Sbjct: 124 KSIKVWSMY------------RQRFLYSLYRHTHWVRCAKFSPDGRLIVS 161
Score = 32.7 bits (73), Expect = 1.6
Identities = 16/38 (42%), Positives = 22/38 (57%), Gaps = 1/38 (2%)
Query: 501 KVVQDLSGEHMGAVWTMKFSHCGRLLASAGQDNVVRIW 538
+++ L G H G V+T+ FS G L AS G D V +W
Sbjct: 261 RLIYTLQG-HTGPVFTVSFSKGGELFASGGADTQVLLW 297
>gi|239787764 WD repeat domain 51A isoform 3 [Homo sapiens]
Length = 369
Score = 69.7 bits (169), Expect = 1e-11
Identities = 73/312 (23%), Positives = 117/312 (37%), Gaps = 69/312 (22%)
Query: 510 HMGAVWTMKFSHCGRLLASAGQDNVVRIWALKNAFDYFNNMRMKYNTEGRVSPSPSQESL 569
H AV + FS G LLAS +D VRIW + N R T V +S
Sbjct: 22 HKDAVTCVNFSPSGHLLASGSRDKTVRIW-VPNVKGESTVFRAHTATVRSVHFCSDGQSF 80
Query: 570 SSSKSDTDTGVCSGTDEDPDDKNAPFRQRPFCKYKGHTADLLDLSWSKN-YFLLSSSMDK 628
++ D V A RQ+ H + +S + ++S+S DK
Sbjct: 81 VTASDDKTVKVW-----------ATHRQKFLFSLSQHINWVRCAKFSPDGRLIVSASDDK 129
Query: 629 TVRLWHISRRECLCCF-QHIDFVTAIAFHPRDDRYFLSGSLDGKLRLWNIPDKKVALWNE 687
TV+LW S REC+ + +H FVT + FHP +G +D +++W++
Sbjct: 130 TVKLWDKSSRECVHSYCEHGGFVTYVDFHPSGTCIAAAG-MDNTVKVWDV---------- 178
Query: 688 VDGQTKLITAANFCQNGKYAVIGTYDGRCIFYDTEHLKYHTQIHVRSTRGRNKVGRKITG 747
T L H Q+H + G
Sbjct: 179 --------------------------------RTHRLLQHYQLH----------SAAVNG 196
Query: 748 IEPLPGENKILVTSNDSRIRLYDLRDLSLSMKYKGYVNSSSQIKASFSHDFTYLVSGSED 807
+ P N ++ S+DS +++ DL + L G+ ++ + +FS Y SG D
Sbjct: 197 LSFHPSGNYLITASSDSTLKILDLMEGRLLYTLHGHQGPATTV--AFSRTGEYFASGGSD 254
Query: 808 KYVYIWSTYHDL 819
+ V +W + D+
Sbjct: 255 EQVMVWKSNFDI 266
Score = 40.0 bits (92), Expect = 0.010
Identities = 58/224 (25%), Positives = 92/224 (41%), Gaps = 34/224 (15%)
Query: 456 SVRDEVFHTD-QDDPSSSDDEGMPYTRPVKFKAAHGFKGPYDFDQIKVVQDLSGEHMGAV 514
+VR F +D Q ++SDD + VK A H K + Q H+ V
Sbjct: 67 TVRSVHFCSDGQSFVTASDD------KTVKVWATHRQKFLFSLSQ----------HINWV 110
Query: 515 WTMKFSHCGRLLASAGQDNVVRIWALKNAFDYFNNMRMKYNTEGRVSPSPSQESLSSSKS 574
KFS GRL+ SA D V++W K++ + ++ V PS ++++
Sbjct: 111 RCAKFSPDGRLIVSASDDKTVKLWD-KSSRECVHSYCEHGGFVTYVDFHPSGTCIAAAGM 169
Query: 575 DTDTGVCSGTDEDPDDKNAPFRQRPFCKYKGHTADLLDLSW--SKNYFLLSSSMDKTVRL 632
D V R Y+ H+A + LS+ S NY L+++S D T+++
Sbjct: 170 DNTVKVWDVR-----------THRLLQHYQLHSAAVNGLSFHPSGNY-LITASSDSTLKI 217
Query: 633 WHISRRECLCCFQ-HIDFVTAIAFHPRDDRYFLSGSLDGKLRLW 675
+ L H T +AF R YF SG D ++ +W
Sbjct: 218 LDLMEGRLLYTLHGHQGPATTVAF-SRTGEYFASGGSDEQVMVW 260
>gi|23199987 WD repeat domain 5B [Homo sapiens]
Length = 330
Score = 69.7 bits (169), Expect = 1e-11
Identities = 86/361 (23%), Positives = 139/361 (38%), Gaps = 83/361 (22%)
Query: 510 HMGAVWTMKFSHCGRLLASAGQDNVVRIWALKNAFD-YFNNMRMKYNTEGRVSPSPSQES 568
H AV ++KFS G LAS+ D ++ IW A+D + +N E
Sbjct: 40 HTEAVSSVKFSPNGEWLASSSADRLIIIW---GAYDGKYEKTLYGHNLE----------- 85
Query: 569 LSSSKSDTDTGVCSGTDEDPDDKNAPFRQRPFCK-YKGHTADLLDLSWS-KNYFLLSSSM 626
+S +D+ +D K R K KGH+ + +++ + ++S S
Sbjct: 86 ISDVAWSSDSSRLVSASDDKTLKLWDVRSGKCLKTLKGHSNYVFCCNFNPPSNLIISGSF 145
Query: 627 DKTVRLWHISRRECLCCFQ-HIDFVTAIAFHPRDDRYFLSGSLDGKLRLWNIPDKKVALW 685
D+TV++W + +CL H D V+A+ F+ +SGS DG R+W+ + L
Sbjct: 146 DETVKIWEVKTGKCLKTLSAHSDPVSAVHFN-CSGSLIVSGSYDGLCRIWDAASGQ-CLK 203
Query: 686 NEVDGQTKLITAANFCQNGKYAVIGTYDGRCIFYDTEHLKYHTQIHVRSTRGRNKVGRKI 745
VD ++ F NGKY + T D +D +RGR
Sbjct: 204 TLVDDDNPPVSFVKFSPNGKYILTATLDNTLKLWD-------------YSRGR------- 243
Query: 746 TGIEPLPGENKILVTSNDSRIRLYDLRDLSLSMKYKGYVNSSSQIKASFS-HDFTYLVSG 804
Y G+ N I A+FS ++VSG
Sbjct: 244 ------------------------------CLKTYTGHKNEKYCIFANFSVTGGKWIVSG 273
Query: 805 SEDKYVYIWSTYHDLSKFTSVRRDRNDFWEGIKAHNAVVTSAIFAPNPSLMLSLDVQSEK 864
SED VYIW+ + + ++ H VV SA P +L+ S ++++K
Sbjct: 274 SEDNLVYIWNL------------QTKEIVQKLQGHTDVVISAACHPTENLIASAALENDK 321
Query: 865 S 865
+
Sbjct: 322 T 322
Score = 48.1 bits (113), Expect = 4e-05
Identities = 49/215 (22%), Positives = 92/215 (42%), Gaps = 32/215 (14%)
Query: 495 YDFDQIKVVQDLSGEHMGAVWTMKFSHCGRLLASAGQDNVVRIW------ALKNAFDYFN 548
+D K ++ L G H V+ F+ L+ S D V+IW LK + +
Sbjct: 110 WDVRSGKCLKTLKG-HSNYVFCCNFNPPSNLIISGSFDETVKIWEVKTGKCLKTLSAHSD 168
Query: 549 NMR-MKYNTEGRVSPSPSQESLSSSKSDTDTGVCSGTDEDPDDKNAPFRQRPFCKYKGHT 607
+ + +N G + S S + L D +G C T D D+ F
Sbjct: 169 PVSAVHFNCSGSLIVSGSYDGLCRIW-DAASGQCLKTLVDDDNPPVSF------------ 215
Query: 608 ADLLDLSWSKN-YFLLSSSMDKTVRLWHISRRECLCCF---QHIDFVTAIAFHPRDDRYF 663
+ +S N ++L++++D T++LW SR CL + ++ + F ++
Sbjct: 216 -----VKFSPNGKYILTATLDNTLKLWDYSRGRCLKTYTGHKNEKYCIFANFSVTGGKWI 270
Query: 664 LSGSLDGKLRLWNIPDKKVALWNEVDGQTKLITAA 698
+SGS D + +WN+ K++ ++ G T ++ +A
Sbjct: 271 VSGSEDNLVYIWNLQTKEIV--QKLQGHTDVVISA 303
Score = 38.1 bits (87), Expect = 0.038
Identities = 28/124 (22%), Positives = 57/124 (45%), Gaps = 10/124 (8%)
Query: 690 GQTKLITAANFCQNGKYAVIGTYDGRCIFYDTEHLKYHTQIHVRSTRGRNKVGRKITGIE 749
G T+ +++ F NG++ + D I + KY ++ G N +I+ +
Sbjct: 39 GHTEAVSSVKFSPNGEWLASSSADRLIIIWGAYDGKYEKTLY-----GHN---LEISDVA 90
Query: 750 PLPGENKILVTSNDSRIRLYDLRDLSLSMKYKGYVNSSSQIKASFSHDFTYLVSGSEDKY 809
++++ S+D ++L+D+R KG+ S+ +F+ ++SGS D+
Sbjct: 91 WSSDSSRLVSASDDKTLKLWDVRSGKCLKTLKGH--SNYVFCCNFNPPSNLIISGSFDET 148
Query: 810 VYIW 813
V IW
Sbjct: 149 VKIW 152
>gi|153791298 mitogen-activated protein kinase organizer 1 [Homo
sapiens]
Length = 315
Score = 63.5 bits (153), Expect = 8e-10
Identities = 61/222 (27%), Positives = 94/222 (42%), Gaps = 15/222 (6%)
Query: 594 PFRQRPFCKYKGHTADLLDLSWS-KNYFLLSSSMDKTVRLWHISRRECLCCFQ-HIDFVT 651
P R Y GH ++LD + S N L S DK V LW ++ + + F+ H V
Sbjct: 54 PLRGTLLRTYSGHGYEVLDAAGSFDNSSLCSGGGDKAVVLWDVASGQVVRKFRGHAGKVN 113
Query: 652 AIAFHPRDDRYFLSGSLDGKLRLWNIPDKKVALWNEVDGQTKLITAANFCQNGKYAVIGT 711
+ F+ + LSGS+D +R W+ ++ +D +++ + A G+
Sbjct: 114 TVQFN-EEATVILSGSIDSSIRCWDCRSRRPEPVQTLDEARDGVSSVKVSDHEILA--GS 170
Query: 712 YDGRCIFYDTEHLKYHTQIHVRSTRGRNKVGRKITGIEPLPGENKILVTSNDSRIRLYDL 771
DGR YD + + VG IT LV+S DS +RL D
Sbjct: 171 VDGRVRRYDLRMGQLFSDY----------VGSPITCTCFSRDGQCTLVSSLDSTLRLLDK 220
Query: 772 RDLSLSMKYKGYVNSSSQIKASFSHDFTYLVSGSEDKYVYIW 813
L +YKG+ N ++ S T++VS SED V+ W
Sbjct: 221 DTGELLGEYKGHKNQEYKLDCCLSERDTHVVSCSEDGKVFFW 262
>gi|14150114 mitogen-activated protein kinase organizer 1 [Homo
sapiens]
Length = 315
Score = 63.5 bits (153), Expect = 8e-10
Identities = 61/222 (27%), Positives = 94/222 (42%), Gaps = 15/222 (6%)
Query: 594 PFRQRPFCKYKGHTADLLDLSWS-KNYFLLSSSMDKTVRLWHISRRECLCCFQ-HIDFVT 651
P R Y GH ++LD + S N L S DK V LW ++ + + F+ H V
Sbjct: 54 PLRGTLLRTYSGHGYEVLDAAGSFDNSSLCSGGGDKAVVLWDVASGQVVRKFRGHAGKVN 113
Query: 652 AIAFHPRDDRYFLSGSLDGKLRLWNIPDKKVALWNEVDGQTKLITAANFCQNGKYAVIGT 711
+ F+ + LSGS+D +R W+ ++ +D +++ + A G+
Sbjct: 114 TVQFN-EEATVILSGSIDSSIRCWDCRSRRPEPVQTLDEARDGVSSVKVSDHEILA--GS 170
Query: 712 YDGRCIFYDTEHLKYHTQIHVRSTRGRNKVGRKITGIEPLPGENKILVTSNDSRIRLYDL 771
DGR YD + + VG IT LV+S DS +RL D
Sbjct: 171 VDGRVRRYDLRMGQLFSDY----------VGSPITCTCFSRDGQCTLVSSLDSTLRLLDK 220
Query: 772 RDLSLSMKYKGYVNSSSQIKASFSHDFTYLVSGSEDKYVYIW 813
L +YKG+ N ++ S T++VS SED V+ W
Sbjct: 221 DTGELLGEYKGHKNQEYKLDCCLSERDTHVVSCSEDGKVFFW 262
>gi|52485606 formin-like 2 [Homo sapiens]
Length = 1092
Score = 62.8 bits (151), Expect = 1e-09
Identities = 96/387 (24%), Positives = 146/387 (37%), Gaps = 70/387 (18%)
Query: 45 KVGNESPVQELKQDVSKKIIESIIEESQKVLQLEDDSLDSKGKELSDQATASPIVARTD- 103
K+G + + +LK S K+ Q +Q D++ G L D T + + R +
Sbjct: 346 KLGLDEYLDKLKHTESDKL--------QVQIQAYLDNVFDVGALLEDAETKNAALERVEE 397
Query: 104 ----LSNIPGLL------AIDQVLPEESQKAESQNTFEETELELKKCFPSDETCEKPVDE 153
+S++ L A+ +++ E Q + + K T K V E
Sbjct: 398 LEENISHLSEKLQDTENEAMSKIVELEKQLMQRNKELDVVREIYKDANTQVHTLRKMVKE 457
Query: 154 TTKLTQTSSTEQLNVLETETEVLNKEAVEVKGGGDV--LEPVSSDSLST-KDFAAVEEVA 210
+ Q ST + + E E + K ++ KG GD+ L V+S +LS + A V
Sbjct: 458 KEEAIQRQSTLEKKIHELEKQGTIK--IQKKGDGDIAILPVVASGTLSMGSEVVAGNSVG 515
Query: 211 PAK---------------PPRHLTPEPDIVASTKKPVPARPPPPTNFPPPRPPPPSRPAP 255
P PP TPE P+P PPPP PPP PPPP P P
Sbjct: 516 PTMGAASSGPLPPPPPPLPPSSDTPETVQNGPVTPPMPPPPPPPPPPPPPPPPPPPPPLP 575
Query: 256 PPRKRKSELEFETLKTPDIDVPKENITSDSLLTASMASESTVKDSQPSLDLASATSGDKI 315
P ET+ P + P L ++ T S P++ S + KI
Sbjct: 576 GPAA-------ETVPAPPLAPP---------LPSAPPLPGT---SSPTVVFNSGLAAVKI 616
Query: 316 -VTAQENGKAPDGQTVAGEVMGPQRPRSNSGRELTDEEILASV-------MIKNLDTGEE 367
+ + P VA + P + E+ DE IL + + K G
Sbjct: 617 KKPIKTKFRMPVFNWVA---LKPNQINGTVFNEIDDERILEDLNVDEFEEIFKTKAQGPA 673
Query: 368 IPLSLAEEKLP-TGINPLTLHIMRRTK 393
I LS +++K+P G N +TL R K
Sbjct: 674 IDLSSSKQKIPQKGSNKVTLLEANRAK 700
>gi|41281564 WD repeat domain 37 [Homo sapiens]
Length = 494
Score = 62.4 bits (150), Expect = 2e-09
Identities = 63/270 (23%), Positives = 115/270 (42%), Gaps = 55/270 (20%)
Query: 602 KYKGHTADLLDLSWSKNY--FLLSSSMDKTVRLWHISRRECLCCFQ-HIDFVTAIAFHPR 658
+Y GH + D+S +K L ++S D T LW I +CL + H+ V +I FHP
Sbjct: 151 EYIGHRDGIWDVSVAKTQPVVLGTASADHTALLWSIETGKCLVKYAGHVGSVNSIKFHP- 209
Query: 659 DDRYFLSGSLDGKLRLWN----------IPDKKVALWNEVDGQTK--------------- 693
++ L+ S D +W + D ++ +EV+ K
Sbjct: 210 SEQLALTASGDQTAHIWRYAVQLPTPQPVADTSISGEDEVECSDKDEPDLDGDVSSDCPT 269
Query: 694 -------------LITAANFCQNGKYAVIGTYDGRCIFYDTEHLKYHTQIHVRSTRGRNK 740
++ A+++ GK AV ++D YD E T V S G ++
Sbjct: 270 IRVPLTSLKSHQGVVIASDWLVGGKQAVTASWDRTANLYDVE-----TSELVHSLTGHDQ 324
Query: 741 VGRKITGIEPLPGENKILVTSNDSRIRLYDLRDLSLSMK--YKGYVNSSSQIKASFSHDF 798
++T P + ++ +S D+ RL+D RD S+ ++G+ ++ + + +
Sbjct: 325 ---ELTHCCTHPTQRLVVTSSRDTTFRLWDFRDPSIHSVNVFQGHTDTVTSAVFTVGDN- 380
Query: 799 TYLVSGSEDKYVYIWSTYHDLSKFTSVRRD 828
+VSGS+D+ V +W + S ++R D
Sbjct: 381 --VVSGSDDRTVKVWDLKNMRSPIATIRTD 408
Score = 55.5 bits (132), Expect = 2e-07
Identities = 64/274 (23%), Positives = 108/274 (39%), Gaps = 34/274 (12%)
Query: 510 HMGAVWTMKFSHCGRLLASAGQDNVVRIWALKNAFDYFNNMRMKYNTEGRVSPSPSQESL 569
H+G+V ++KF +L +A D IW +Y + P+P Q
Sbjct: 198 HVGSVNSIKFHPSEQLALTASGDQTAHIW--------------RYAVQ---LPTP-QPVA 239
Query: 570 SSSKSDTDTGVCSGTDEDPDD----KNAPFRQRPFCKYKGHTADLLDLSWSKN-YFLLSS 624
+S S D CS DE D + P + P K H ++ W +++
Sbjct: 240 DTSISGEDEVECSDKDEPDLDGDVSSDCPTIRVPLTSLKSHQGVVIASDWLVGGKQAVTA 299
Query: 625 SMDKTVRLWHISRRECLCCFQ-HIDFVTAIAFHPRDDRYFLSGSLDGKLRLWNIPDKKVA 683
S D+T L+ + E + H +T HP R ++ S D RLW+ D +
Sbjct: 300 SWDRTANLYDVETSELVHSLTGHDQELTHCCTHPTQ-RLVVTSSRDTTFRLWDFRDPSIH 358
Query: 684 LWNEVDGQTKLITAANFCQNGKYAVIGTYDGRCIFYDTEHLKYHTQIHVRSTRGRNKVGR 743
N G T +T+A F G V G+ D +D +++ RS +
Sbjct: 359 SVNVFQGHTDTVTSAVFTV-GDNVVSGSDDRTVKVWDLKNM--------RSPIATIRTDS 409
Query: 744 KITGIEPLPGENKILVTSNDSRIRLYDLRDLSLS 777
I I G+ I + ++ ++RL+D+ + L+
Sbjct: 410 AINRINVCVGQKIIALPHDNRQVRLFDMSGVRLA 443
>gi|53759148 retinoblastoma binding protein 5 [Homo sapiens]
Length = 538
Score = 61.6 bits (148), Expect = 3e-09
Identities = 75/316 (23%), Positives = 127/316 (40%), Gaps = 34/316 (10%)
Query: 606 HTADLLDLSWSKN-YFLLSSSMDKTVRLWHISRRECLCCFQHIDFVTAIAFHPRDDRYFL 664
H + L WS++ + L+S+S D V W + +C F+ + + +HPRD L
Sbjct: 65 HIHPVCSLCWSRDGHKLVSASTDNIVSQWDVLSGDCDQRFRFPSPILKVQYHPRDQNKVL 124
Query: 665 SGSLDGKLRLWNIPDKKVALWNEVDGQTKLITAANFCQNGKYAVIGTYDGRCIFYDTEHL 724
+ + + D K + VD + L A+F + G+Y G G+ + T+
Sbjct: 125 VCPMKSAPVMLTLSDSKHVVL-PVDDDSDLNVVASFDRRGEYIYTGNAKGKILVLKTDSQ 183
Query: 725 KYHTQIHVRSTRGRNKVGRKITGIEPLPGENKILVTSNDSRIRLYDLRDL---------S 775
V T G + I IE + L+ + D IR+YD R++
Sbjct: 184 DLVASFRV--TTGTSNT-TAIKSIEFARKGSCFLINTADRIIRVYDGREILTCGRDGEPE 240
Query: 776 LSMKYKGYVNSSSQIKASFSHDFTYLVSGSEDKY-VYIW-STYHDLSKFTSVRRDR---N 830
K + VN + K FS D Y+V+GS ++ +YIW + +L K R +
Sbjct: 241 PMQKLQDLVNRTPWKKCCFSGDGEYIVAGSARQHALYIWEKSIGNLVKILHGTRGELLLD 300
Query: 831 DFWEGIK--------------AHNAVVTSAIFAPNPSLMLSLDVQSEKSEGNEKSEDAEV 876
W ++ A N V + FAP+ L +V+ E+ E ED +
Sbjct: 301 VAWHPVRPIIASISSGVVSIWAQNQVENWSAFAPD-FKELDENVEYEERESEFDIEDEDK 359
Query: 877 LDATPSGIMKTDNTEV 892
+ +G ++ EV
Sbjct: 360 SEPEQTGADAAEDEEV 375
>gi|19913371 transducin (beta)-like 1 X-linked receptor 1 [Homo
sapiens]
Length = 514
Score = 60.8 bits (146), Expect = 5e-09
Identities = 79/360 (21%), Positives = 144/360 (40%), Gaps = 55/360 (15%)
Query: 433 GKSVKRAKHLAEEYGERAINKVKSVRDEVFHTDQDDPSSSDDEGMPYTRPVKFKAAHGFK 492
G S R +L+E + V +R + QD PS+ D + + A +
Sbjct: 189 GDSTARIWNLSENSTSGSTQLV--LRHCIREGGQDVPSNKDVTSLDWNSEGTLLATGSYD 246
Query: 493 GPYDFDQIKV----VQDLSGEHMGAVWTMKFSHCGRLLASAGQDNVVRIW-----ALKNA 543
G F +I + G+H G ++ +K++ G + SAG D IW K
Sbjct: 247 G---FARIWTKDGNLASTLGQHKGPIFALKWNKKGNFILSAGVDKTTIIWDAHTGEAKQQ 303
Query: 544 FDYFNNMRMKYNTEGRVSPSPSQESLSSSKSDTDTGVCS-GTDEDPDDKNAPFRQRPFCK 602
F + + + + + S + +S +D VC G D RP
Sbjct: 304 FPFHSAPALDVDWQ-------SNNTFASCSTDMCIHVCKLGQD------------RPIKT 344
Query: 603 YKGHTADLLDLSWSKNYFLLSS-SMDKTVRLWHISRRECLCCFQ-HIDFVTAIAF----- 655
++GHT ++ + W LL+S S D T+++W + + C+ Q H + I +
Sbjct: 345 FQGHTNEVNAIKWDPTGNLLASCSDDMTLKIWSMKQDNCVHDLQAHNKEIYTIKWSPTGP 404
Query: 656 ---HPRDDRYFLSGSLDGKLRLWNIPDKKVALWNEVDGQTKLITAANFCQNGKYAVIGTY 712
+P + S S D +RLW++ D+ + + Q + + A F +G+Y G++
Sbjct: 405 GTNNPNANLMLASASFDSTVRLWDV-DRGICIHTLTKHQEPVYSVA-FSPDGRYLASGSF 462
Query: 713 DGRCIFYDTEHLKYHTQIHVRSTRGRNKVGRKITGIEPLPGENKILVTSNDSRIRLYDLR 772
D ++T+ T V S RG + +K+ +++D + + DLR
Sbjct: 463 DKCVHIWNTQ-----TGALVHSYRGTGGIFEVCWN----AAGDKVGASASDGSVCVLDLR 513
Score = 45.8 bits (107), Expect = 2e-04
Identities = 74/319 (23%), Positives = 123/319 (38%), Gaps = 28/319 (8%)
Query: 510 HMGAVWTMKFSHCGRLLASAGQDNVVRIWAL-KNAFDYFNNMRMKYNTEGRVSPSPSQES 568
H V+ ++ LLAS D+ RIW L +N+ + +++ PS +
Sbjct: 168 HESEVFICAWNPVSDLLASGSGDSTARIWNLSENSTSGSTQLVLRHCIREGGQDVPSNKD 227
Query: 569 LSSSKSDTDTGVCSGTDEDPDDKNAPFRQRPFCKYKG-HTADLLDLSWS-KNYFLLSSSM 626
++S +++ G T + G H + L W+ K F+LS+ +
Sbjct: 228 VTSLDWNSE-GTLLATGSYDGFARIWTKDGNLASTLGQHKGPIFALKWNKKGNFILSAGV 286
Query: 627 DKTVRLWHISRRECLCCFQHIDFVTAIAFHP--RDDRYFLSGSLDGKLRLWNI-PDKKVA 683
DKT +W E Q F +A A + + F S S D + + + D+ +
Sbjct: 287 DKTTIIWDAHTGEAK---QQFPFHSAPALDVDWQSNNTFASCSTDMCIHVCKLGQDRPIK 343
Query: 684 LWNEVDGQTKLITAANFCQNGKYAVIGTYDGRCIFYDTEHLKYHTQIHVRSTRGRNKVGR 743
+ G T + A + G + D + +K +H + NK
Sbjct: 344 TF---QGHTNEVNAIKWDPTGNLLASCSDDMTLKIWS---MKQDNCVH--DLQAHNKEIY 395
Query: 744 KITGIEPLPGENK------ILVTSNDSRIRLYDL-RDLSLSMKYKGYVNSSSQIKASFSH 796
I PG N + S DS +RL+D+ R + + K + +FS
Sbjct: 396 TIKWSPTGPGTNNPNANLMLASASFDSTVRLWDVDRGICIHTLTK---HQEPVYSVAFSP 452
Query: 797 DFTYLVSGSEDKYVYIWST 815
D YL SGS DK V+IW+T
Sbjct: 453 DGRYLASGSFDKCVHIWNT 471
>gi|13376840 WD repeat domain 61 [Homo sapiens]
Length = 305
Score = 60.5 bits (145), Expect = 7e-09
Identities = 53/194 (27%), Positives = 93/194 (47%), Gaps = 18/194 (9%)
Query: 623 SSSMDKTVRLWHISRRECLCCFQH--IDFVTAIAFHPRDDRYFLSGSLDGKLRLWNIPDK 680
SSS+D +RLW + + + +D T +AF P D +Y +G+ GK+ ++ +
Sbjct: 81 SSSLDAHIRLWDLENGKQIKSIDAGPVDAWT-LAFSP-DSQYLATGTHVGKVNIFGVESG 138
Query: 681 KVALWNEVDGQTKLITAANFCQNGKYAVIGTYDGRCIFYDTEHLKYHTQIHVRSTRGRNK 740
K +D + K I + + +GKY G DG +D K + + G
Sbjct: 139 KKEY--SLDTRGKFILSIAYSPDGKYLASGAIDGIINIFDIATGKL-----LHTLEGHAM 191
Query: 741 VGRKITGIEPLPGENKILVT-SNDSRIRLYDLRDLSLSMKYKGYVNSSSQIKASFSHDFT 799
R +T ++++LVT S+D I++YD++ +L+ G+ +S + +F D T
Sbjct: 192 PIRSLT----FSPDSQLLVTASDDGYIKIYDVQHANLAGTLSGH--ASWVLNVAFCPDDT 245
Query: 800 YLVSGSEDKYVYIW 813
+ VS S DK V +W
Sbjct: 246 HFVSSSSDKSVKVW 259
Score = 41.6 bits (96), Expect = 0.003
Identities = 36/153 (23%), Positives = 61/153 (39%), Gaps = 12/153 (7%)
Query: 665 SGSLDGKLRLWNIPDKKVALWNEVDGQTKLITAANFCQNGKYAVIGTYDGRCIFYDTEHL 724
S SLD +RLW++ + K +D F + +Y GT+ G+ + E
Sbjct: 81 SSSLDAHIRLWDLENGKQI--KSIDAGPVDAWTLAFSPDSQYLATGTHVGKVNIFGVESG 138
Query: 725 KYHTQIHVRSTRGRNKVGRKITGIEPLPGENKILVTSNDSRIRLYDLRDLSLSMKYKGYV 784
K + R G+ I I P + + D I ++D+ L +G+
Sbjct: 139 KKEYSLDTR--------GKFILSIAYSPDGKYLASGAIDGIINIFDIATGKLLHTLEGHA 190
Query: 785 NSSSQIKASFSHDFTYLVSGSEDKYVYIWSTYH 817
+ +FS D LV+ S+D Y+ I+ H
Sbjct: 191 MPIRSL--TFSPDSQLLVTASDDGYIKIYDVQH 221
Score = 39.3 bits (90), Expect = 0.017
Identities = 59/283 (20%), Positives = 112/283 (39%), Gaps = 42/283 (14%)
Query: 498 DQIKVVQDLSGEHMGAVWTMKFSHCGRLLASAGQDNVVRIWALKNAFDYFNNMRMKYNTE 557
+++ + L G +G V ++ SH + AS+ D +R+W L+ N ++K
Sbjct: 52 ERLDLQWSLEGHQLGVV-SVDISHTLPIAASSSLDAHIRLWDLE------NGKQIKSIDA 104
Query: 558 GRVSPSPSQESLSSSKSDTDT--------GVCSGTDEDPDDKNAPFRQRPFCKYKGHTAD 609
G V S S T T GV SG E D F
Sbjct: 105 GPVDAWTLAFSPDSQYLATGTHVGKVNIFGVESGKKEYSLDTRGKF-------------- 150
Query: 610 LLDLSWSKN-YFLLSSSMDKTVRLWHISRRECLCCFQ-HIDFVTAIAFHPRDDRYFLSGS 667
+L +++S + +L S ++D + ++ I+ + L + H + ++ F P D + ++ S
Sbjct: 151 ILSIAYSPDGKYLASGAIDGIINIFDIATGKLLHTLEGHAMPIRSLTFSP-DSQLLVTAS 209
Query: 668 LDGKLRLWNIPDKKVALWNEVDGQTKLITAANFCQNGKYAVIGTYDGRCIFYDTEHLKYH 727
DG ++++++ +A + G + FC + + V + D +D +
Sbjct: 210 DDGYIKIYDVQHANLA--GTLSGHASWVLNVAFCPDDTHFVSSSSDKSVKVWD---VGTR 264
Query: 728 TQIHVRSTRGRNKVGRKITGIEPLPGENKILVTSNDSRIRLYD 770
T +H G K G +KI+ +D I +YD
Sbjct: 265 TCVHTFFDHQDQVWGVKYNG-----NGSKIVSVGDDQEIHIYD 302
Score = 35.4 bits (80), Expect = 0.24
Identities = 36/173 (20%), Positives = 76/173 (43%), Gaps = 27/173 (15%)
Query: 514 VWTMKFSHCGRLLASAGQDNVVRIWALKNAFDYFNNMRMKYNTEGRVSP------SPSQE 567
+ ++ +S G+ LAS D ++ I+ + ++ + EG P SP +
Sbjct: 151 ILSIAYSPDGKYLASGAIDGIINIFDIATG-------KLLHTLEGHAMPIRSLTFSPDSQ 203
Query: 568 SLSSSKSDTDTGVCSGTDEDPDDKNAPFRQRPFCKYKGHTADLLDLSWSKN-YFLLSSSM 626
L ++ D G + D ++A GH + +L++++ + +SSS
Sbjct: 204 LLVTASDD-------GYIKIYDVQHANLAGT----LSGHASWVLNVAFCPDDTHFVSSSS 252
Query: 627 DKTVRLWHISRRECL-CCFQHIDFVTAIAFHPRDDRYFLSGSLDGKLRLWNIP 678
DK+V++W + R C+ F H D V + ++ + G D ++ +++ P
Sbjct: 253 DKSVKVWDVGTRTCVHTFFDHQDQVWGVKYNGNGSKIVSVGD-DQEIHIYDCP 304
>gi|11055998 guanine nucleotide-binding protein, beta-4 subunit
[Homo sapiens]
Length = 340
Score = 59.3 bits (142), Expect = 2e-08
Identities = 76/321 (23%), Positives = 130/321 (40%), Gaps = 29/321 (9%)
Query: 499 QIKVVQDLSGEHMGAVWTMKFSHCGRLLASAGQDNVVRIWALKNAFDYFNNMRMKYNTEG 558
Q++ + L G H+ ++ M + + RLL SA QD + IW D + +M
Sbjct: 44 QMRTRRTLRG-HLAKIYAMHWGYDSRLLVSASQDGKLIIW------DSYTTNKM------ 90
Query: 559 RVSPSPSQESLSSSKSDTDTGV-CSGTDEDPDDKNAPFRQ---RPFCKYKGHTADLLDLS 614
P S ++ + + + V C G D N R+ R + GHT L
Sbjct: 91 HAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELPGHTGYLSCCR 150
Query: 615 WSKNYFLLSSSMDKTVRLWHISRRECLCCFQ-HIDFVTAIAFHPRDDRYFLSGSLDGKLR 673
+ + +++SS D T LW I + F H V +++ P D R F+SG+ D +
Sbjct: 151 FLDDSQIVTSSGDTTCALWDIETAQQTTTFTGHSGDVMSLSLSP-DMRTFVSGACDASSK 209
Query: 674 LWNIPDKKVALWNEVDGQTKLITAANFCQNGKYAVIGTYDGRCIFYDTEHLKYHTQIHVR 733
LW+I D G I A +F NG G+ D C +D L+ ++ +
Sbjct: 210 LWDIRDGMCR--QSFTGHVSDINAVSFFPNGYAFATGSDDATCRLFD---LRADQELLLY 264
Query: 734 STRGRNKVGRKITGIEPLPGENKILVTSNDSRIRLYDLRDLSLSMKYKGYVNSSSQIKAS 793
S + + IT + +L +D ++D + G+ N S +
Sbjct: 265 S---HDNIICGITSVAFSKSGRLLLAGYDDFNCNVWDTLKGDRAGVLAGHDNRVSCL--G 319
Query: 794 FSHDFTYLVSGSEDKYVYIWS 814
+ D + +GS D ++ IW+
Sbjct: 320 VTDDGMAVATGSWDSFLRIWN 340
>gi|4885105 chromatin assembly factor 1 subunit B [Homo sapiens]
Length = 559
Score = 59.3 bits (142), Expect = 2e-08
Identities = 54/192 (28%), Positives = 93/192 (48%), Gaps = 23/192 (11%)
Query: 514 VWTMKFSH--CGRL--LASAGQDNVVRIWAL------KNAFDYFNNMRMKYNTEGRVSPS 563
V+++ F H GR+ LASAG D VRIW + K ++ +N+ V S
Sbjct: 16 VYSLDFQHGTAGRIHRLASAGVDTNVRIWKVEKGPDGKAIVEFLSNLARHTKAVNVVRFS 75
Query: 564 PSQESLSSSKSDTDTGVCSGTD-EDP------DDKNAPFRQRPFCKYK---GHTADLLDL 613
P+ E L+S D + D ++P D+ A + + K GH D+ D+
Sbjct: 76 PTGEILASGGDDAVILLWKVNDNKEPEQIAFQDEDEAQLNKENWTVVKTLRGHLEDVYDI 135
Query: 614 SWSKNYFLL-SSSMDKTVRLWHISRRECLCCF-QHIDFVTAIAFHPRDDRYFLSGSLDGK 671
W+ + L+ S+S+D T +W +S+ + + F +H +V + + P +Y + S D
Sbjct: 136 CWATDGNLMASASVDNTAIIWDVSKGQKISIFNEHKSYVQGVTWDPL-GQYVATLSCDRV 194
Query: 672 LRLWNIPDKKVA 683
LR+++I K+VA
Sbjct: 195 LRVYSIQKKRVA 206
>gi|213021190 transducin beta-like 1X isoform b [Homo sapiens]
Length = 526
Score = 58.9 bits (141), Expect = 2e-08
Identities = 54/226 (23%), Positives = 98/226 (43%), Gaps = 38/226 (16%)
Query: 508 GEHMGAVWTMKFSHCGRLLASAGQDNVVRIW-----ALKNAFDYFNNMRMKYNTEGRVSP 562
G+H G ++ +K++ G + SAG D IW K F + + + + +
Sbjct: 275 GQHKGPIFALKWNRKGNYILSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQ----- 329
Query: 563 SPSQESLSSSKSDTDTGVCS-GTDEDPDDKNAPFRQRPFCKYKGHTADLLDLSWSKNYFL 621
+ + +S +D VC G D RP ++GHT ++ + W + L
Sbjct: 330 --NNTTFASCSTDMCIHVCRLGCD------------RPVKTFQGHTNEVNAIKWDPSGML 375
Query: 622 LSS-SMDKTVRLWHISRRECLCCFQ-HIDFVTAIAF--------HPRDDRYFLSGSLDGK 671
L+S S D T+++W + + C+ Q H + I + +P + S S D
Sbjct: 376 LASCSDDMTLKIWSMKQEVCIHDLQAHNKEIYTIKWSPTGPATSNPNSNIMLASASFDST 435
Query: 672 LRLWNIPDKKVALWNEVDGQTKLITAANFCQNGKYAVIGTYDGRCI 717
+RLW+I ++ V Q + + A F +GKY G++D +C+
Sbjct: 436 VRLWDI-ERGVCTHTLTKHQEPVYSVA-FSPDGKYLASGSFD-KCV 478
Score = 44.3 bits (103), Expect = 5e-04
Identities = 72/316 (22%), Positives = 126/316 (39%), Gaps = 22/316 (6%)
Query: 510 HMGAVWTMKFSHCGRLLASAGQDNVVRIWAL-KNAFDYFNNMRMKYNTEGRVSPSPSQES 568
H V+ ++ LLAS D+ RIW L +N+ + +++ PS +
Sbjct: 180 HESEVFICAWNPVSDLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPSNKD 239
Query: 569 LSSSKSDTDTGVCSGTDEDPDDKNAPFRQRPFCKYKGHTADLLDLSWS-KNYFLLSSSMD 627
++S +T+ + + D + H + L W+ K ++LS+ +D
Sbjct: 240 VTSLDWNTNGTLLATGSYDGFARIWTEDGNLASTLGQHKGPIFALKWNRKGNYILSAGVD 299
Query: 628 KTVRLWHISRRECLCCFQHIDFVTAIAFHP--RDDRYFLSGSLDGKLRLWNIP-DKKVAL 684
KT +W E Q F +A A +++ F S S D + + + D+ V
Sbjct: 300 KTTIIWDAHTGEAK---QQFPFHSAPALDVDWQNNTTFASCSTDMCIHVCRLGCDRPVKT 356
Query: 685 WNEVDGQTKLITAANFCQNGKYAVIGTYDGRCIFYDTEHLKYHTQIHVRSTRGRNKVGRK 744
+ G T + A + +G + D + +K IH + K
Sbjct: 357 FQ---GHTNEVNAIKWDPSGMLLASCSDDMTLKIWS---MKQEVCIHDLQAHNKEIYTIK 410
Query: 745 ITGIEPL---PGENKILVTSN-DSRIRLYDL-RDLSLSMKYKGYVNSSSQIKASFSHDFT 799
+ P P N +L +++ DS +RL+D+ R + K + +FS D
Sbjct: 411 WSPTGPATSNPNSNIMLASASFDSTVRLWDIERGVCTHTLTK---HQEPVYSVAFSPDGK 467
Query: 800 YLVSGSEDKYVYIWST 815
YL SGS DK V+IW+T
Sbjct: 468 YLASGSFDKCVHIWNT 483
Score = 37.4 bits (85), Expect = 0.064
Identities = 37/179 (20%), Positives = 71/179 (39%), Gaps = 35/179 (19%)
Query: 510 HMGAVWTMKFSHCGRLLASAGQDNVVRIWALKNAFDYFNNMR-------MKYNTEGRVSP 562
H V +K+ G LLAS D ++IW++K + +K++ G +
Sbjct: 360 HTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQEVCIHDLQAHNKEIYTIKWSPTGPATS 419
Query: 563 SPSQESLSSSKS--------DTDTGVCSGTDEDPDDKNAPFRQRPFCKYKGHTADLLDLS 614
+P+ + +S S D + GVC+ T H + ++
Sbjct: 420 NPNSNIMLASASFDSTVRLWDIERGVCTHT------------------LTKHQEPVYSVA 461
Query: 615 WSKN-YFLLSSSMDKTVRLWHISRRECLCCFQHIDFVTAIAFHPRDDRYFLSGSLDGKL 672
+S + +L S S DK V +W+ + ++ + + ++ R D+ S S DG +
Sbjct: 462 FSPDGKYLASGSFDKCVHIWNTQSGNLVHSYRGTGGIFEVCWNARGDKVGASAS-DGSV 519
>gi|213021188 transducin beta-like 1X isoform b [Homo sapiens]
Length = 526
Score = 58.9 bits (141), Expect = 2e-08
Identities = 54/226 (23%), Positives = 98/226 (43%), Gaps = 38/226 (16%)
Query: 508 GEHMGAVWTMKFSHCGRLLASAGQDNVVRIW-----ALKNAFDYFNNMRMKYNTEGRVSP 562
G+H G ++ +K++ G + SAG D IW K F + + + + +
Sbjct: 275 GQHKGPIFALKWNRKGNYILSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQ----- 329
Query: 563 SPSQESLSSSKSDTDTGVCS-GTDEDPDDKNAPFRQRPFCKYKGHTADLLDLSWSKNYFL 621
+ + +S +D VC G D RP ++GHT ++ + W + L
Sbjct: 330 --NNTTFASCSTDMCIHVCRLGCD------------RPVKTFQGHTNEVNAIKWDPSGML 375
Query: 622 LSS-SMDKTVRLWHISRRECLCCFQ-HIDFVTAIAF--------HPRDDRYFLSGSLDGK 671
L+S S D T+++W + + C+ Q H + I + +P + S S D
Sbjct: 376 LASCSDDMTLKIWSMKQEVCIHDLQAHNKEIYTIKWSPTGPATSNPNSNIMLASASFDST 435
Query: 672 LRLWNIPDKKVALWNEVDGQTKLITAANFCQNGKYAVIGTYDGRCI 717
+RLW+I ++ V Q + + A F +GKY G++D +C+
Sbjct: 436 VRLWDI-ERGVCTHTLTKHQEPVYSVA-FSPDGKYLASGSFD-KCV 478
Score = 44.3 bits (103), Expect = 5e-04
Identities = 72/316 (22%), Positives = 126/316 (39%), Gaps = 22/316 (6%)
Query: 510 HMGAVWTMKFSHCGRLLASAGQDNVVRIWAL-KNAFDYFNNMRMKYNTEGRVSPSPSQES 568
H V+ ++ LLAS D+ RIW L +N+ + +++ PS +
Sbjct: 180 HESEVFICAWNPVSDLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPSNKD 239
Query: 569 LSSSKSDTDTGVCSGTDEDPDDKNAPFRQRPFCKYKGHTADLLDLSWS-KNYFLLSSSMD 627
++S +T+ + + D + H + L W+ K ++LS+ +D
Sbjct: 240 VTSLDWNTNGTLLATGSYDGFARIWTEDGNLASTLGQHKGPIFALKWNRKGNYILSAGVD 299
Query: 628 KTVRLWHISRRECLCCFQHIDFVTAIAFHP--RDDRYFLSGSLDGKLRLWNIP-DKKVAL 684
KT +W E Q F +A A +++ F S S D + + + D+ V
Sbjct: 300 KTTIIWDAHTGEAK---QQFPFHSAPALDVDWQNNTTFASCSTDMCIHVCRLGCDRPVKT 356
Query: 685 WNEVDGQTKLITAANFCQNGKYAVIGTYDGRCIFYDTEHLKYHTQIHVRSTRGRNKVGRK 744
+ G T + A + +G + D + +K IH + K
Sbjct: 357 FQ---GHTNEVNAIKWDPSGMLLASCSDDMTLKIWS---MKQEVCIHDLQAHNKEIYTIK 410
Query: 745 ITGIEPL---PGENKILVTSN-DSRIRLYDL-RDLSLSMKYKGYVNSSSQIKASFSHDFT 799
+ P P N +L +++ DS +RL+D+ R + K + +FS D
Sbjct: 411 WSPTGPATSNPNSNIMLASASFDSTVRLWDIERGVCTHTLTK---HQEPVYSVAFSPDGK 467
Query: 800 YLVSGSEDKYVYIWST 815
YL SGS DK V+IW+T
Sbjct: 468 YLASGSFDKCVHIWNT 483
Score = 37.4 bits (85), Expect = 0.064
Identities = 37/179 (20%), Positives = 71/179 (39%), Gaps = 35/179 (19%)
Query: 510 HMGAVWTMKFSHCGRLLASAGQDNVVRIWALKNAFDYFNNMR-------MKYNTEGRVSP 562
H V +K+ G LLAS D ++IW++K + +K++ G +
Sbjct: 360 HTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQEVCIHDLQAHNKEIYTIKWSPTGPATS 419
Query: 563 SPSQESLSSSKS--------DTDTGVCSGTDEDPDDKNAPFRQRPFCKYKGHTADLLDLS 614
+P+ + +S S D + GVC+ T H + ++
Sbjct: 420 NPNSNIMLASASFDSTVRLWDIERGVCTHT------------------LTKHQEPVYSVA 461
Query: 615 WSKN-YFLLSSSMDKTVRLWHISRRECLCCFQHIDFVTAIAFHPRDDRYFLSGSLDGKL 672
+S + +L S S DK V +W+ + ++ + + ++ R D+ S S DG +
Sbjct: 462 FSPDGKYLASGSFDKCVHIWNTQSGNLVHSYRGTGGIFEVCWNARGDKVGASAS-DGSV 519
>gi|213021186 transducin beta-like 1X isoform a [Homo sapiens]
Length = 577
Score = 58.9 bits (141), Expect = 2e-08
Identities = 54/226 (23%), Positives = 98/226 (43%), Gaps = 38/226 (16%)
Query: 508 GEHMGAVWTMKFSHCGRLLASAGQDNVVRIW-----ALKNAFDYFNNMRMKYNTEGRVSP 562
G+H G ++ +K++ G + SAG D IW K F + + + + +
Sbjct: 326 GQHKGPIFALKWNRKGNYILSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQ----- 380
Query: 563 SPSQESLSSSKSDTDTGVCS-GTDEDPDDKNAPFRQRPFCKYKGHTADLLDLSWSKNYFL 621
+ + +S +D VC G D RP ++GHT ++ + W + L
Sbjct: 381 --NNTTFASCSTDMCIHVCRLGCD------------RPVKTFQGHTNEVNAIKWDPSGML 426
Query: 622 LSS-SMDKTVRLWHISRRECLCCFQ-HIDFVTAIAF--------HPRDDRYFLSGSLDGK 671
L+S S D T+++W + + C+ Q H + I + +P + S S D
Sbjct: 427 LASCSDDMTLKIWSMKQEVCIHDLQAHNKEIYTIKWSPTGPATSNPNSNIMLASASFDST 486
Query: 672 LRLWNIPDKKVALWNEVDGQTKLITAANFCQNGKYAVIGTYDGRCI 717
+RLW+I ++ V Q + + A F +GKY G++D +C+
Sbjct: 487 VRLWDI-ERGVCTHTLTKHQEPVYSVA-FSPDGKYLASGSFD-KCV 529
Score = 44.3 bits (103), Expect = 5e-04
Identities = 72/316 (22%), Positives = 126/316 (39%), Gaps = 22/316 (6%)
Query: 510 HMGAVWTMKFSHCGRLLASAGQDNVVRIWAL-KNAFDYFNNMRMKYNTEGRVSPSPSQES 568
H V+ ++ LLAS D+ RIW L +N+ + +++ PS +
Sbjct: 231 HESEVFICAWNPVSDLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPSNKD 290
Query: 569 LSSSKSDTDTGVCSGTDEDPDDKNAPFRQRPFCKYKGHTADLLDLSWS-KNYFLLSSSMD 627
++S +T+ + + D + H + L W+ K ++LS+ +D
Sbjct: 291 VTSLDWNTNGTLLATGSYDGFARIWTEDGNLASTLGQHKGPIFALKWNRKGNYILSAGVD 350
Query: 628 KTVRLWHISRRECLCCFQHIDFVTAIAFHP--RDDRYFLSGSLDGKLRLWNIP-DKKVAL 684
KT +W E Q F +A A +++ F S S D + + + D+ V
Sbjct: 351 KTTIIWDAHTGEAK---QQFPFHSAPALDVDWQNNTTFASCSTDMCIHVCRLGCDRPVKT 407
Query: 685 WNEVDGQTKLITAANFCQNGKYAVIGTYDGRCIFYDTEHLKYHTQIHVRSTRGRNKVGRK 744
+ G T + A + +G + D + +K IH + K
Sbjct: 408 FQ---GHTNEVNAIKWDPSGMLLASCSDDMTLKIWS---MKQEVCIHDLQAHNKEIYTIK 461
Query: 745 ITGIEPL---PGENKILVTSN-DSRIRLYDL-RDLSLSMKYKGYVNSSSQIKASFSHDFT 799
+ P P N +L +++ DS +RL+D+ R + K + +FS D
Sbjct: 462 WSPTGPATSNPNSNIMLASASFDSTVRLWDIERGVCTHTLTK---HQEPVYSVAFSPDGK 518
Query: 800 YLVSGSEDKYVYIWST 815
YL SGS DK V+IW+T
Sbjct: 519 YLASGSFDKCVHIWNT 534
Score = 37.4 bits (85), Expect = 0.064
Identities = 37/179 (20%), Positives = 71/179 (39%), Gaps = 35/179 (19%)
Query: 510 HMGAVWTMKFSHCGRLLASAGQDNVVRIWALKNAFDYFNNMR-------MKYNTEGRVSP 562
H V +K+ G LLAS D ++IW++K + +K++ G +
Sbjct: 411 HTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQEVCIHDLQAHNKEIYTIKWSPTGPATS 470
Query: 563 SPSQESLSSSKS--------DTDTGVCSGTDEDPDDKNAPFRQRPFCKYKGHTADLLDLS 614
+P+ + +S S D + GVC+ T H + ++
Sbjct: 471 NPNSNIMLASASFDSTVRLWDIERGVCTHT------------------LTKHQEPVYSVA 512
Query: 615 WSKN-YFLLSSSMDKTVRLWHISRRECLCCFQHIDFVTAIAFHPRDDRYFLSGSLDGKL 672
+S + +L S S DK V +W+ + ++ + + ++ R D+ S S DG +
Sbjct: 513 FSPDGKYLASGSFDKCVHIWNTQSGNLVHSYRGTGGIFEVCWNARGDKVGASAS-DGSV 570
>gi|5032159 transducin beta-like 1X isoform a [Homo sapiens]
Length = 577
Score = 58.9 bits (141), Expect = 2e-08
Identities = 54/226 (23%), Positives = 98/226 (43%), Gaps = 38/226 (16%)
Query: 508 GEHMGAVWTMKFSHCGRLLASAGQDNVVRIW-----ALKNAFDYFNNMRMKYNTEGRVSP 562
G+H G ++ +K++ G + SAG D IW K F + + + + +
Sbjct: 326 GQHKGPIFALKWNRKGNYILSAGVDKTTIIWDAHTGEAKQQFPFHSAPALDVDWQ----- 380
Query: 563 SPSQESLSSSKSDTDTGVCS-GTDEDPDDKNAPFRQRPFCKYKGHTADLLDLSWSKNYFL 621
+ + +S +D VC G D RP ++GHT ++ + W + L
Sbjct: 381 --NNTTFASCSTDMCIHVCRLGCD------------RPVKTFQGHTNEVNAIKWDPSGML 426
Query: 622 LSS-SMDKTVRLWHISRRECLCCFQ-HIDFVTAIAF--------HPRDDRYFLSGSLDGK 671
L+S S D T+++W + + C+ Q H + I + +P + S S D
Sbjct: 427 LASCSDDMTLKIWSMKQEVCIHDLQAHNKEIYTIKWSPTGPATSNPNSNIMLASASFDST 486
Query: 672 LRLWNIPDKKVALWNEVDGQTKLITAANFCQNGKYAVIGTYDGRCI 717
+RLW+I ++ V Q + + A F +GKY G++D +C+
Sbjct: 487 VRLWDI-ERGVCTHTLTKHQEPVYSVA-FSPDGKYLASGSFD-KCV 529
Score = 44.3 bits (103), Expect = 5e-04
Identities = 72/316 (22%), Positives = 126/316 (39%), Gaps = 22/316 (6%)
Query: 510 HMGAVWTMKFSHCGRLLASAGQDNVVRIWAL-KNAFDYFNNMRMKYNTEGRVSPSPSQES 568
H V+ ++ LLAS D+ RIW L +N+ + +++ PS +
Sbjct: 231 HESEVFICAWNPVSDLLASGSGDSTARIWNLNENSNGGSTQLVLRHCIREGGHDVPSNKD 290
Query: 569 LSSSKSDTDTGVCSGTDEDPDDKNAPFRQRPFCKYKGHTADLLDLSWS-KNYFLLSSSMD 627
++S +T+ + + D + H + L W+ K ++LS+ +D
Sbjct: 291 VTSLDWNTNGTLLATGSYDGFARIWTEDGNLASTLGQHKGPIFALKWNRKGNYILSAGVD 350
Query: 628 KTVRLWHISRRECLCCFQHIDFVTAIAFHP--RDDRYFLSGSLDGKLRLWNIP-DKKVAL 684
KT +W E Q F +A A +++ F S S D + + + D+ V
Sbjct: 351 KTTIIWDAHTGEAK---QQFPFHSAPALDVDWQNNTTFASCSTDMCIHVCRLGCDRPVKT 407
Query: 685 WNEVDGQTKLITAANFCQNGKYAVIGTYDGRCIFYDTEHLKYHTQIHVRSTRGRNKVGRK 744
+ G T + A + +G + D + +K IH + K
Sbjct: 408 FQ---GHTNEVNAIKWDPSGMLLASCSDDMTLKIWS---MKQEVCIHDLQAHNKEIYTIK 461
Query: 745 ITGIEPL---PGENKILVTSN-DSRIRLYDL-RDLSLSMKYKGYVNSSSQIKASFSHDFT 799
+ P P N +L +++ DS +RL+D+ R + K + +FS D
Sbjct: 462 WSPTGPATSNPNSNIMLASASFDSTVRLWDIERGVCTHTLTK---HQEPVYSVAFSPDGK 518
Query: 800 YLVSGSEDKYVYIWST 815
YL SGS DK V+IW+T
Sbjct: 519 YLASGSFDKCVHIWNT 534
Score = 37.4 bits (85), Expect = 0.064
Identities = 37/179 (20%), Positives = 71/179 (39%), Gaps = 35/179 (19%)
Query: 510 HMGAVWTMKFSHCGRLLASAGQDNVVRIWALKNAFDYFNNMR-------MKYNTEGRVSP 562
H V +K+ G LLAS D ++IW++K + +K++ G +
Sbjct: 411 HTNEVNAIKWDPSGMLLASCSDDMTLKIWSMKQEVCIHDLQAHNKEIYTIKWSPTGPATS 470
Query: 563 SPSQESLSSSKS--------DTDTGVCSGTDEDPDDKNAPFRQRPFCKYKGHTADLLDLS 614
+P+ + +S S D + GVC+ T H + ++
Sbjct: 471 NPNSNIMLASASFDSTVRLWDIERGVCTHT------------------LTKHQEPVYSVA 512
Query: 615 WSKN-YFLLSSSMDKTVRLWHISRRECLCCFQHIDFVTAIAFHPRDDRYFLSGSLDGKL 672
+S + +L S S DK V +W+ + ++ + + ++ R D+ S S DG +
Sbjct: 513 FSPDGKYLASGSFDKCVHIWNTQSGNLVHSYRGTGGIFEVCWNARGDKVGASAS-DGSV 570
>gi|7657381 PRP19/PSO4 pre-mRNA processing factor 19 homolog [Homo
sapiens]
Length = 504
Score = 58.5 bits (140), Expect = 3e-08
Identities = 70/267 (26%), Positives = 116/267 (43%), Gaps = 23/267 (8%)
Query: 564 PSQESLSSSKSDTDTGVCSGTDEDPD--DKNAPFRQRPFCKYKGHTADLLDLSWSKNYFL 621
P +L SDT+ + G D++ DK++ ++ KGHT + + + + L
Sbjct: 222 PGILALDLCPSDTNKILTGGADKNVVVFDKSS---EQILATLKGHTKKVTSVVFHPSQDL 278
Query: 622 L-SSSMDKTVRLWHISRRECLCCFQ-HIDFVTAIAFHPRDDRYFLSGSLDGKLRLWNIPD 679
+ S+S D T+R+W + C+ + H VT ++ H D Y LS S D + W D
Sbjct: 279 VFSASPDATIRIWSVPNASCVQVVRAHESAVTGLSLHATGD-YLLSSSDD---QYWAFSD 334
Query: 680 KKVA-LWNEVDGQTK--LITAANFCQNGKYAVIGTYDGRCIFYDTEHLKYHTQIHVRSTR 736
+ + +V +T +T A F +G GT D + +D LK T +V +
Sbjct: 335 IQTGRVLTKVTDETSGCSLTCAQFHPDGLIFGTGTMDSQIKIWD---LKERT--NVANFP 389
Query: 737 GRNKVGRKITGIEPLPGENKILVTSNDSRIRLYDLRDLSLSMKYKGYVNSSSQIKASFSH 796
G + IT I + ++DS ++L+DLR L + K N+ F
Sbjct: 390 GHS---GPITSIAFSENGYYLATAADDSSVKLWDLRKLK-NFKTLQLDNNFEVKSLIFDQ 445
Query: 797 DFTYLVSGSEDKYVYIWSTYHDLSKFT 823
TYL G D +YI + ++ FT
Sbjct: 446 SGTYLALGGTDVQIYICKQWTEILHFT 472
Score = 30.4 bits (67), Expect = 7.9
Identities = 15/48 (31%), Positives = 26/48 (54%), Gaps = 1/48 (2%)
Query: 510 HMGAVWTMKFSHCGRLLASAGQDNVVRIWALKNAFDYFNNMRMKYNTE 557
H G + ++ FS G LA+A D+ V++W L+ F +++ N E
Sbjct: 391 HSGPITSIAFSENGYYLATAADDSSVKLWDLRK-LKNFKTLQLDNNFE 437
>gi|11321585 guanine nucleotide-binding protein, beta-1 subunit
[Homo sapiens]
Length = 340
Score = 58.2 bits (139), Expect = 4e-08
Identities = 75/323 (23%), Positives = 128/323 (39%), Gaps = 33/323 (10%)
Query: 499 QIKVVQDLSGEHMGAVWTMKFSHCGRLLASAGQDNVVRIWALKNAFDYFNNMRMKYNTEG 558
Q++ + L G H+ ++ M + RLL SA QD + IW D + T
Sbjct: 44 QMRTRRTLRG-HLAKIYAMHWGTDSRLLVSASQDGKLIIW------DSY--------TTN 88
Query: 559 RVSPSPSQESLSSSKSDTDTG---VCSGTDEDPDDKNAPFRQ---RPFCKYKGHTADLLD 612
+V P + S + + +G C G D N R+ R + GHT L
Sbjct: 89 KVHAIPLRSSWVMTCAYAPSGNYVACGGLDNICSIYNLKTREGNVRVSRELAGHTGYLSC 148
Query: 613 LSWSKNYFLLSSSMDKTVRLWHISRRECLCCFQ-HIDFVTAIAFHPRDDRYFLSGSLDGK 671
+ + +++SS D T LW I + F H V +++ P D R F+SG+ D
Sbjct: 149 CRFLDDNQIVTSSGDTTCALWDIETGQQTTTFTGHTGDVMSLSLAP-DTRLFVSGACDAS 207
Query: 672 LRLWNIPDKKVALWNEVDGQTKLITAANFCQNGKYAVIGTYDGRCIFYDTEHLKYHTQIH 731
+LW++ ++ G I A F NG G+ D C +D L+ ++
Sbjct: 208 AKLWDV--REGMCRQTFTGHESDINAICFFPNGNAFATGSDDATCRLFD---LRADQEL- 261
Query: 732 VRSTRGRNKVGRKITGIEPLPGENKILVTSNDSRIRLYDLRDLSLSMKYKGYVNSSSQIK 791
T + + IT + +L +D ++D + G+ N S +
Sbjct: 262 --MTYSHDNIICGITSVSFSKSGRLLLAGYDDFNCNVWDALKADRAGVLAGHDNRVSCL- 318
Query: 792 ASFSHDFTYLVSGSEDKYVYIWS 814
+ D + +GS D ++ IW+
Sbjct: 319 -GVTDDGMAVATGSWDSFLKIWN 340
>gi|70909324 sperm associated antigen 16 isoform 1 [Homo sapiens]
Length = 631
Score = 57.4 bits (137), Expect = 6e-08
Identities = 66/257 (25%), Positives = 102/257 (39%), Gaps = 35/257 (13%)
Query: 564 PSQESLSSSKSDTDT---GVCSGTDEDPDDKNAPFRQRPFCKYKGHTADLLDLSW-SKNY 619
PS + L++S DT +C G ++GH+ + +W S
Sbjct: 404 PSGDKLATSSGDTTVKLWDLCKGDC--------------ILTFEGHSRAVWSCTWHSCGN 449
Query: 620 FLLSSSMDKTVRLWHISRRECLC-CFQHIDFVTAIAFHPRDDRYFLSGSLDGKLRLWNIP 678
F+ SSS+DKT ++W ++ C C + H D V +I F P + L+ S D L +W
Sbjct: 450 FVASSSLDKTSKIWDVNSERCRCTLYGHTDSVNSIEFFPFSNT-LLTSSADKTLSIW--- 505
Query: 679 DKKVALWNE-VDGQTKLITAANFCQNGKYAVIGTYDGRCIFYDTEHLKYHTQIHVRSTRG 737
D + + + + G I A F G G +D L I + + G
Sbjct: 506 DARTGICEQSLYGHMHSINDAIFDPRGHMIASCDACGVTKLWDFRKLLPIVSIDIGPSPG 565
Query: 738 RNKVGRKITGIEPLPGENKILVTSNDSRIRLYDLRDLSLSMKYKGYVNSSSQIKASFSHD 797
N+V +G + S + I L DL+ + K G+ N + + FSHD
Sbjct: 566 -NEVNFDSSG-------RVLAQASGNGVIHLLDLKSGEIH-KLMGHENEAHTV--VFSHD 614
Query: 798 FTYLVSGSEDKYVYIWS 814
L SG D V WS
Sbjct: 615 GEILFSGGSDGTVRTWS 631
Score = 37.0 bits (84), Expect = 0.084
Identities = 32/160 (20%), Positives = 65/160 (40%), Gaps = 15/160 (9%)
Query: 631 RLWHI-SRREC---LCCFQHIDFVTAIAFHPRDDRYFLSGSLDGKLRLWNIPDKKVALWN 686
RLW + +C L F H D+++ FHP D+ + S D ++LW++ L
Sbjct: 374 RLWKVLGLPKCNVLLTGFGHTDWLSDCCFHPSGDK-LATSSGDTTVKLWDLCKGDCIL-- 430
Query: 687 EVDGQTKLITAANFCQNGKYAVIGTYDGRCIFYDTEHLKYHTQIHVRSTRGRNKVGRKIT 746
+G ++ + + + G + + D +D + ++ + +
Sbjct: 431 TFEGHSRAVWSCTWHSCGNFVASSSLDKTSKIWDVNSERCRCTLYGHTD--------SVN 482
Query: 747 GIEPLPGENKILVTSNDSRIRLYDLRDLSLSMKYKGYVNS 786
IE P N +L +S D + ++D R G+++S
Sbjct: 483 SIEFFPFSNTLLTSSADKTLSIWDARTGICEQSLYGHMHS 522
Score = 30.8 bits (68), Expect = 6.0
Identities = 13/30 (43%), Positives = 16/30 (53%)
Query: 510 HMGAVWTMKFSHCGRLLASAGQDNVVRIWA 539
H T+ FSH G +L S G D VR W+
Sbjct: 602 HENEAHTVVFSHDGEILFSGGSDGTVRTWS 631
>gi|189571685 WD repeat, sterile alpha motif and U-box domain
containing 1 [Homo sapiens]
Length = 476
Score = 57.4 bits (137), Expect = 6e-08
Identities = 66/271 (24%), Positives = 109/271 (40%), Gaps = 26/271 (9%)
Query: 595 FRQRPFCKYKGHTADLLDLSWSKN-YFLLSSSMDKTVRLWHISRRECLCCFQHIDF--VT 651
F + P K HT + +S + + L S S D T LW+ + L + V
Sbjct: 42 FTELPHSPLKFHTYAVHCCCFSPSGHILASCSTDGTTVLWNTENGQMLAVMEQPSGSPVR 101
Query: 652 AIAFHPRDDRYFLSGSLDGKLRLWNIPDKKVALWNEV-DGQTKLITAANFCQNGKYAVIG 710
F P D SG+ DG + LWN K+ V DG + A F NG + V G
Sbjct: 102 VCQFSP-DSTCLASGAADGTVVLWNAQSYKLYRCGSVKDGS---LAACAFSPNGSFFVTG 157
Query: 711 TYDGRCIFYDTEHLKYHTQ-IHVRSTRGRNKVGRKITGIEPLPGENKILVTSNDSRIRLY 769
+ G +D + H++ H + + ++ E ++ D +++++
Sbjct: 158 SSCGDLTVWDDKMRCLHSEKAHDLGITCCDFSSQPVSDGEQGLQFFRLASCGQDCQVKIW 217
Query: 770 DL---RDLSLSMKYKGYVNS--SSQIKASFSHDFTYLVSGSEDKYVYIWSTYHDLSKFTS 824
+ L +KYK ++ + + +FSHD LVSGS DK V ++ T
Sbjct: 218 IVSFTHILGFELKYKSTLSGHCAPVLACAFSHDGQMLVSGSVDKSVIVYDT--------- 268
Query: 825 VRRDRNDFWEGIKAHNAVVTSAIFAPNPSLM 855
+ + + H VT+ FAPN L+
Sbjct: 269 ---NTENILHTLTQHTRYVTTCAFAPNTLLL 296
Score = 32.7 bits (73), Expect = 1.6
Identities = 38/173 (21%), Positives = 63/173 (36%), Gaps = 50/173 (28%)
Query: 526 LASAGQDNVVRIWALKNAFDYFNNMRMKYNTEGRVSPSPSQESLSSSKSDTDTGVCSGTD 585
LAS GQD V+IW + +F + +KY +
Sbjct: 205 LASCGQDCQVKIWIV--SFTHILGFELKYKS----------------------------- 233
Query: 586 EDPDDKNAPFRQRPFCKYKGHTADLLDLSWSKN-YFLLSSSMDKTVRLWHISRRECL-CC 643
GH A +L ++S + L+S S+DK+V ++ + L
Sbjct: 234 ----------------TLSGHCAPVLACAFSHDGQMLVSGSVDKSVIVYDTNTENILHTL 277
Query: 644 FQHIDFVTAIAFHPRDDRYFLSGSLDGKLRLWNIPDKKVALWNEVDGQTKLIT 696
QH +VT AF P + +GS+D + +W + + + Q K T
Sbjct: 278 TQHTRYVTTCAFAP-NTLLLATGSMDKTVNIWQFDLETLCQARRTEHQLKQFT 329
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.311 0.129 0.371
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 38,370,925
Number of Sequences: 37866
Number of extensions: 2125889
Number of successful extensions: 33802
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 542
Number of HSP's successfully gapped in prelim test: 868
Number of HSP's that attempted gapping in prelim test: 15837
Number of HSP's gapped (non-prelim): 9635
length of query: 913
length of database: 18,247,518
effective HSP length: 111
effective length of query: 802
effective length of database: 14,044,392
effective search space: 11263602384
effective search space used: 11263602384
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.