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Search of human proteins with 4507397
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4507397 transcription factor 2 [Homo sapiens]
(557 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4507397 transcription factor 2 [Homo sapiens] 1115 0.0
gi|134304844 hepatic nuclear factor-1-alpha [Homo sapiens] 545 e-155
gi|209180434 homeobox containing 1 [Homo sapiens] 73 8e-13
gi|47059040 homeobox containing 1 [Homo sapiens] 73 8e-13
gi|4505619 paired box 7 isoform 1 [Homo sapiens] 47 6e-05
gi|7524359 paired box 7 isoform 2 [Homo sapiens] 47 6e-05
gi|207029223 paired box 7 isoform 3 [Homo sapiens] 47 6e-05
gi|188219638 paired box 3 isoform PAX3i [Homo sapiens] 44 3e-04
gi|31563344 paired box 3 isoform PAX3e [Homo sapiens] 44 3e-04
gi|31563342 paired box 3 isoform PAX3d [Homo sapiens] 44 3e-04
gi|31563340 paired box 3 isoform PAX3 [Homo sapiens] 44 3e-04
gi|19920317 cytoskeleton-associated protein 4 [Homo sapiens] 41 0.003
gi|157743257 POU domain, class 6, transcription factor 2 [Homo s... 41 0.003
gi|171543895 ataxin 2 [Homo sapiens] 40 0.007
gi|95147342 chromodomain helicase DNA binding protein 9 [Homo sa... 39 0.010
gi|167736355 mucin 4 isoform a [Homo sapiens] 39 0.016
gi|31563348 paired box 3 isoform PAX3g [Homo sapiens] 38 0.021
gi|31563346 paired box 3 isoform PAX3h [Homo sapiens] 38 0.021
gi|157739945 tetratricopeptide repeat, ankyrin repeat and coiled... 38 0.028
gi|119395716 forkhead box C1 [Homo sapiens] 37 0.048
gi|219275578 SIX homeobox 2 [Homo sapiens] 37 0.048
gi|5902024 paired mesoderm homeobox 1 isoform pmx-1a [Homo sapiens] 37 0.048
gi|12707577 paired mesoderm homeobox 1 isoform pmx-1b [Homo sapi... 37 0.048
gi|58530876 melanoma antigen family C, 1 [Homo sapiens] 37 0.062
gi|209969838 transportin 2 (importin 3, karyopherin beta 2b) iso... 36 0.081
gi|209969836 transportin 2 (importin 3, karyopherin beta 2b) iso... 36 0.081
gi|48675813 transportin 2 (importin 3, karyopherin beta 2b) isof... 36 0.081
gi|189083681 paired box gene 6 isoform a [Homo sapiens] 36 0.11
gi|4580424 paired box gene 6 isoform b [Homo sapiens] 36 0.11
gi|4505615 paired box gene 6 isoform a [Homo sapiens] 36 0.11
>gi|4507397 transcription factor 2 [Homo sapiens]
Length = 557
Score = 1115 bits (2884), Expect = 0.0
Identities = 557/557 (100%), Positives = 557/557 (100%)
Query: 1 MVSKLTSLQQELLSALLSSGVTKEVLVQALEELLPSPNFGVKLETLPLSPGSGAEPDTKP 60
MVSKLTSLQQELLSALLSSGVTKEVLVQALEELLPSPNFGVKLETLPLSPGSGAEPDTKP
Sbjct: 1 MVSKLTSLQQELLSALLSSGVTKEVLVQALEELLPSPNFGVKLETLPLSPGSGAEPDTKP 60
Query: 61 VFHTLTNGHAKGRLSGDEGSEDGDDYDTPPILKELQALNTEEAAEQRAEVDRMLSEDPWR 120
VFHTLTNGHAKGRLSGDEGSEDGDDYDTPPILKELQALNTEEAAEQRAEVDRMLSEDPWR
Sbjct: 61 VFHTLTNGHAKGRLSGDEGSEDGDDYDTPPILKELQALNTEEAAEQRAEVDRMLSEDPWR 120
Query: 121 AAKMIKGYMQQHNIPQREVVDVTGLNQSHLSQHLNKGTPMKTQKRAALYTWYVRKQREIL 180
AAKMIKGYMQQHNIPQREVVDVTGLNQSHLSQHLNKGTPMKTQKRAALYTWYVRKQREIL
Sbjct: 121 AAKMIKGYMQQHNIPQREVVDVTGLNQSHLSQHLNKGTPMKTQKRAALYTWYVRKQREIL 180
Query: 181 RQFNQTVQSSGNMTDKSSQDQLLFLFPEFSQQSHGPGQSDDACSEPTNKKMRRNRFKWGP 240
RQFNQTVQSSGNMTDKSSQDQLLFLFPEFSQQSHGPGQSDDACSEPTNKKMRRNRFKWGP
Sbjct: 181 RQFNQTVQSSGNMTDKSSQDQLLFLFPEFSQQSHGPGQSDDACSEPTNKKMRRNRFKWGP 240
Query: 241 ASQQILYQAYDRQKNPSKEEREALVEECNRAECLQRGVSPSKAHGLGSNLVTEVRVYNWF 300
ASQQILYQAYDRQKNPSKEEREALVEECNRAECLQRGVSPSKAHGLGSNLVTEVRVYNWF
Sbjct: 241 ASQQILYQAYDRQKNPSKEEREALVEECNRAECLQRGVSPSKAHGLGSNLVTEVRVYNWF 300
Query: 301 ANRRKEEAFRQKLAMDAYSSNQTHSLNPLLSHGSPHHQPSSSPPNKLSGVRYSQQGNNEI 360
ANRRKEEAFRQKLAMDAYSSNQTHSLNPLLSHGSPHHQPSSSPPNKLSGVRYSQQGNNEI
Sbjct: 301 ANRRKEEAFRQKLAMDAYSSNQTHSLNPLLSHGSPHHQPSSSPPNKLSGVRYSQQGNNEI 360
Query: 361 TSSSTISHHGNSAMVTSQSVLQQVSPASLDPGHNLLSPDGKMISVSGGGLPPVSTLTNIH 420
TSSSTISHHGNSAMVTSQSVLQQVSPASLDPGHNLLSPDGKMISVSGGGLPPVSTLTNIH
Sbjct: 361 TSSSTISHHGNSAMVTSQSVLQQVSPASLDPGHNLLSPDGKMISVSGGGLPPVSTLTNIH 420
Query: 421 SLSHHNPQQSQNLIMTPLSGVMAIAQSLNTSQAQSVPVINSVAGSLAALQPVQFSQQLHS 480
SLSHHNPQQSQNLIMTPLSGVMAIAQSLNTSQAQSVPVINSVAGSLAALQPVQFSQQLHS
Sbjct: 421 SLSHHNPQQSQNLIMTPLSGVMAIAQSLNTSQAQSVPVINSVAGSLAALQPVQFSQQLHS 480
Query: 481 PHQQPLMQQSPGSHMAQQPFMAAVTQLQNSHMYAHKQEPPQYSHTSRFPSAMVVTDTSSI 540
PHQQPLMQQSPGSHMAQQPFMAAVTQLQNSHMYAHKQEPPQYSHTSRFPSAMVVTDTSSI
Sbjct: 481 PHQQPLMQQSPGSHMAQQPFMAAVTQLQNSHMYAHKQEPPQYSHTSRFPSAMVVTDTSSI 540
Query: 541 STLTNMSSSKQCPLQAW 557
STLTNMSSSKQCPLQAW
Sbjct: 541 STLTNMSSSKQCPLQAW 557
>gi|134304844 hepatic nuclear factor-1-alpha [Homo sapiens]
Length = 631
Score = 545 bits (1405), Expect = e-155
Identities = 313/577 (54%), Positives = 378/577 (65%), Gaps = 62/577 (10%)
Query: 1 MVSKLTSLQQELLSALLSSGVTKEVLVQALEELLPSPNFGVKLETLPLSPGSGAEPDTKP 60
MVSKL+ LQ ELL+ALL SG++KE L+QAL E P G PL G
Sbjct: 1 MVSKLSQLQTELLAALLESGLSKEALIQALGEPGPYLLAGEG----PLDKGESCGGGRGE 56
Query: 61 VFHTLTNGHAKGRLSGDEGSEDGDDYDTPPILKELQALNTEEAAEQRAEVDRMLSEDPWR 120
+ L NG + R S DE +DG+D+ TPPILKEL+ L+ EEAA Q+A V+ +L EDPWR
Sbjct: 57 LAE-LPNGLGETRGSEDETDDDGEDF-TPPILKELENLSPEEAAHQKAVVETLLQEDPWR 114
Query: 121 AAKMIKGYMQQHNIPQREVVDVTGLNQSHLSQHLNKGTPMKTQKRAALYTWYVRKQREIL 180
AKM+K Y+QQHNIPQREVVD TGLNQSHLSQHLNKGTPMKTQKRAALYTWYVRKQRE+
Sbjct: 115 VAKMVKSYLQQHNIPQREVVDTTGLNQSHLSQHLNKGTPMKTQKRAALYTWYVRKQREVA 174
Query: 181 RQFNQTVQSSGNMTDKSSQDQLLFLFPEFSQQSHGPGQSDDACSEPTNKKMRRNRFKWGP 240
+QF Q G + ++ + D+L PT KK RRNRFKWGP
Sbjct: 175 QQFTHAGQ--GGLIEEPTGDEL-----------------------PT-KKGRRNRFKWGP 208
Query: 241 ASQQILYQAYDRQKNPSKEEREALVEECNRAECLQRGVSPSKAHGLGSNLVTEVRVYNWF 300
ASQQIL+QAY+RQKNPSKEERE LVEECNRAEC+QRGVSPS+A GLGSNLVTEVRVYNWF
Sbjct: 209 ASQQILFQAYERQKNPSKEERETLVEECNRAECIQRGVSPSQAQGLGSNLVTEVRVYNWF 268
Query: 301 ANRRKEEAFRQKLAMDAYSSNQT-HSLNPLL-SHGSPHHQPSSSPPNKLSGVRYSQQGNN 358
ANRRKEEAFR KLAMD YS P L +H SP P + P+K+ GVRY Q +
Sbjct: 269 ANRRKEEAFRHKLAMDTYSGPPPGPGPGPALPAHSSPGLPPPALSPSKVHGVRYGQPATS 328
Query: 359 EITSSSTISHHGNSAMVTSQSVLQQVSPASLDPGHNLLSPDGKMISVSGGGLPPVSTLTN 418
E ++ + +VT + L QVSP L+P H+LLS + K++S +GG LPPVSTLT
Sbjct: 329 E---TAEVPSSSGGPLVTVSTPLHQVSPTGLEPSHSLLSTEAKLVSAAGGPLPPVSTLTA 385
Query: 419 IHSLSHHNP---QQSQNLIMTPLSGVMAIAQ--------------------SLNTSQAQS 455
+HSL +P QQ QNLIM L GVM I L ++QAQS
Sbjct: 386 LHSLEQTSPGLNQQPQNLIMASLPGVMTIGPGEPASLGPTFTNTGASTLVIGLASTQAQS 445
Query: 456 VPVINSVAGSLAALQPVQFSQQLHSPHQQPLMQQSPGSHMAQQPFMAAVTQLQNSH-MYA 514
VPVINS+ SL LQPVQFSQ LH +QQPLM SH+ Q PFMA + QLQ+ H +Y+
Sbjct: 446 VPVINSMGSSLTTLQPVQFSQPLHPSYQQPLMPPVQ-SHVTQSPFMATMAQLQSPHALYS 504
Query: 515 HKQEPPQYSHTSRFPSAMVVTDTSSISTLTNMSSSKQ 551
HK E QY+HT P M++TDT+++S L +++ +KQ
Sbjct: 505 HKPEVAQYTHTGLLPQTMLITDTTNLSALASLTPTKQ 541
>gi|209180434 homeobox containing 1 [Homo sapiens]
Length = 420
Score = 72.8 bits (177), Expect = 8e-13
Identities = 96/392 (24%), Positives = 149/392 (38%), Gaps = 71/392 (18%)
Query: 4 KLTSLQQELLSALLSSGVTKEVLVQALEEL----------------LPSPNFGVKLETLP 47
+ T Q +LL L +G+TK ++ ALE L ++G +P
Sbjct: 21 RFTIEQIDLLQRLRRTGMTKHEILHALETLDRLDQEHSDKFGRRSSYGGSSYGNSTNNVP 80
Query: 48 LSPG----------SGAEP------DTKPVFHTLT-NGHAKG-RLSGDEGSEDGDDYDTP 89
S SG P DT P T NG RLS G Y
Sbjct: 81 ASSSTATASTQTQHSGMSPSPSNSYDTSPQPCTTNQNGRENNERLSTSNGKMSPTRYHAN 140
Query: 90 PILKELQALN-TEEAAEQRAEVDRMLSEDPWRAAKMIKGYMQQHNIPQREVVDVTGLNQS 148
+ + + +EE + +V+ ++ D + IK ++ I Q V VTG++QS
Sbjct: 141 SMGQRSYSFEASEEDLDVDDKVEELMRRDSSVIKEEIKAFLANRRISQAVVAQVTGISQS 200
Query: 149 HLSQHL-NKGTPMKTQKRAALYTWYVRKQREILRQFNQTVQSSGNMTDKSSQDQLLFLFP 207
+S L +G+ + QK+ A Y WY L + N S +D P
Sbjct: 201 RISHWLLQQGSDLSEQKKRAFYRWYQ------LEKTNPGATLSMRPAPIPIED------P 248
Query: 208 EFSQQSHGPGQSDDACSEPTNKKMRRNRFKWGPASQQILYQAYDRQKNPSKEEREALVEE 267
E+ Q + + T + R +RF W ++ ++ + P + +RE +
Sbjct: 249 EWRQTP-----PPVSATSGTFRLRRGSRFTWRKECLAVMESYFNENQYPDEAKREEIANA 303
Query: 268 CNRAECLQRGVSPSKAHGLGSNLVTEVRVYNWFANRRKEEAFRQKLAMDAYSSNQTHSLN 327
CN +Q+ P K VT ++VYNWFANRRKE R +
Sbjct: 304 CNAV--IQK---PGKKLS-DLERVTSLKVYNWFANRRKEIKRRANIEAAI---------- 347
Query: 328 PLLSHGSPHHQPSS-SPPNKLSGVRYSQQGNN 358
L SHG P S + + G YS+Q ++
Sbjct: 348 -LESHGIDVQSPGGHSNSDDVDGNDYSEQDDS 378
>gi|47059040 homeobox containing 1 [Homo sapiens]
Length = 420
Score = 72.8 bits (177), Expect = 8e-13
Identities = 96/392 (24%), Positives = 149/392 (38%), Gaps = 71/392 (18%)
Query: 4 KLTSLQQELLSALLSSGVTKEVLVQALEEL----------------LPSPNFGVKLETLP 47
+ T Q +LL L +G+TK ++ ALE L ++G +P
Sbjct: 21 RFTIEQIDLLQRLRRTGMTKHEILHALETLDRLDQEHSDKFGRRSSYGGSSYGNSTNNVP 80
Query: 48 LSPG----------SGAEP------DTKPVFHTLT-NGHAKG-RLSGDEGSEDGDDYDTP 89
S SG P DT P T NG RLS G Y
Sbjct: 81 ASSSTATASTQTQHSGMSPSPSNSYDTSPQPCTTNQNGRENNERLSTSNGKMSPTRYHAN 140
Query: 90 PILKELQALN-TEEAAEQRAEVDRMLSEDPWRAAKMIKGYMQQHNIPQREVVDVTGLNQS 148
+ + + +EE + +V+ ++ D + IK ++ I Q V VTG++QS
Sbjct: 141 SMGQRSYSFEASEEDLDVDDKVEELMRRDSSVIKEEIKAFLANRRISQAVVAQVTGISQS 200
Query: 149 HLSQHL-NKGTPMKTQKRAALYTWYVRKQREILRQFNQTVQSSGNMTDKSSQDQLLFLFP 207
+S L +G+ + QK+ A Y WY L + N S +D P
Sbjct: 201 RISHWLLQQGSDLSEQKKRAFYRWYQ------LEKTNPGATLSMRPAPIPIED------P 248
Query: 208 EFSQQSHGPGQSDDACSEPTNKKMRRNRFKWGPASQQILYQAYDRQKNPSKEEREALVEE 267
E+ Q + + T + R +RF W ++ ++ + P + +RE +
Sbjct: 249 EWRQTP-----PPVSATSGTFRLRRGSRFTWRKECLAVMESYFNENQYPDEAKREEIANA 303
Query: 268 CNRAECLQRGVSPSKAHGLGSNLVTEVRVYNWFANRRKEEAFRQKLAMDAYSSNQTHSLN 327
CN +Q+ P K VT ++VYNWFANRRKE R +
Sbjct: 304 CNAV--IQK---PGKKLS-DLERVTSLKVYNWFANRRKEIKRRANIEAAI---------- 347
Query: 328 PLLSHGSPHHQPSS-SPPNKLSGVRYSQQGNN 358
L SHG P S + + G YS+Q ++
Sbjct: 348 -LESHGIDVQSPGGHSNSDDVDGNDYSEQDDS 378
>gi|4505619 paired box 7 isoform 1 [Homo sapiens]
Length = 520
Score = 46.6 bits (109), Expect = 6e-05
Identities = 62/244 (25%), Positives = 98/244 (40%), Gaps = 45/244 (18%)
Query: 226 PTNKKMRRNRFKWGPASQQILYQAYDRQKNPSKEEREALVEECNRAECLQRGVSPSKAHG 285
P +K RR+R + + L +A++R P RE L +
Sbjct: 212 PLKRKQRRSRTTFTAEQLEELEKAFERTHYPDIYTREELAQRTK---------------- 255
Query: 286 LGSNLVTEVRVYNWFANRRKEEAFRQKLAMDAYSSNQTHSLNPLLSHGSPHHQPSSSPPN 345
+TE RV WF+NRR +R++ +NQ + N LL G P + PP
Sbjct: 256 -----LTEARVQVWFSNRRAR--WRKQA-----GANQLAAFNHLLPGGFPPTGMPTLPPY 303
Query: 346 KLSGVRY-----SQQGNNEITSSSTI----SHHGN-----SAMVTSQSVLQQVSPASL-D 390
+L Y SQ G + + + H G +A TS + + S +S D
Sbjct: 304 QLPDSTYPTTTISQDGGSTVHRPQPLPPSTMHQGGLAAAAAAADTSSAYGARHSFSSYSD 363
Query: 391 PGHNLLSPDGKMISVSGGGLPPVSTLTNIHSLSHHNPQQSQNLIMTPLSGVMAIAQSLNT 450
N +P M VS G P V ++ + + S PQ + ++PL G + A S++
Sbjct: 364 SFMNPAAPSNHMNPVSNGLSPQVMSI--LGNPSAVPPQPQADFSISPLHGGLDSATSISA 421
Query: 451 SQAQ 454
S +Q
Sbjct: 422 SCSQ 425
>gi|7524359 paired box 7 isoform 2 [Homo sapiens]
Length = 518
Score = 46.6 bits (109), Expect = 6e-05
Identities = 62/244 (25%), Positives = 98/244 (40%), Gaps = 45/244 (18%)
Query: 226 PTNKKMRRNRFKWGPASQQILYQAYDRQKNPSKEEREALVEECNRAECLQRGVSPSKAHG 285
P +K RR+R + + L +A++R P RE L +
Sbjct: 210 PLKRKQRRSRTTFTAEQLEELEKAFERTHYPDIYTREELAQRTK---------------- 253
Query: 286 LGSNLVTEVRVYNWFANRRKEEAFRQKLAMDAYSSNQTHSLNPLLSHGSPHHQPSSSPPN 345
+TE RV WF+NRR +R++ +NQ + N LL G P + PP
Sbjct: 254 -----LTEARVQVWFSNRRAR--WRKQA-----GANQLAAFNHLLPGGFPPTGMPTLPPY 301
Query: 346 KLSGVRY-----SQQGNNEITSSSTI----SHHGN-----SAMVTSQSVLQQVSPASL-D 390
+L Y SQ G + + + H G +A TS + + S +S D
Sbjct: 302 QLPDSTYPTTTISQDGGSTVHRPQPLPPSTMHQGGLAAAAAAADTSSAYGARHSFSSYSD 361
Query: 391 PGHNLLSPDGKMISVSGGGLPPVSTLTNIHSLSHHNPQQSQNLIMTPLSGVMAIAQSLNT 450
N +P M VS G P V ++ + + S PQ + ++PL G + A S++
Sbjct: 362 SFMNPAAPSNHMNPVSNGLSPQVMSI--LGNPSAVPPQPQADFSISPLHGGLDSATSISA 419
Query: 451 SQAQ 454
S +Q
Sbjct: 420 SCSQ 423
>gi|207029223 paired box 7 isoform 3 [Homo sapiens]
Length = 505
Score = 46.6 bits (109), Expect = 6e-05
Identities = 62/244 (25%), Positives = 98/244 (40%), Gaps = 45/244 (18%)
Query: 226 PTNKKMRRNRFKWGPASQQILYQAYDRQKNPSKEEREALVEECNRAECLQRGVSPSKAHG 285
P +K RR+R + + L +A++R P RE L +
Sbjct: 212 PLKRKQRRSRTTFTAEQLEELEKAFERTHYPDIYTREELAQRTK---------------- 255
Query: 286 LGSNLVTEVRVYNWFANRRKEEAFRQKLAMDAYSSNQTHSLNPLLSHGSPHHQPSSSPPN 345
+TE RV WF+NRR +R++ +NQ + N LL G P + PP
Sbjct: 256 -----LTEARVQVWFSNRRAR--WRKQA-----GANQLAAFNHLLPGGFPPTGMPTLPPY 303
Query: 346 KLSGVRY-----SQQGNNEITSSSTI----SHHGN-----SAMVTSQSVLQQVSPASL-D 390
+L Y SQ G + + + H G +A TS + + S +S D
Sbjct: 304 QLPDSTYPTTTISQDGGSTVHRPQPLPPSTMHQGGLAAAAAAADTSSAYGARHSFSSYSD 363
Query: 391 PGHNLLSPDGKMISVSGGGLPPVSTLTNIHSLSHHNPQQSQNLIMTPLSGVMAIAQSLNT 450
N +P M VS G P V ++ + + S PQ + ++PL G + A S++
Sbjct: 364 SFMNPAAPSNHMNPVSNGLSPQVMSI--LGNPSAVPPQPQADFSISPLHGGLDSATSISA 421
Query: 451 SQAQ 454
S +Q
Sbjct: 422 SCSQ 425
>gi|188219638 paired box 3 isoform PAX3i [Homo sapiens]
Length = 483
Score = 44.3 bits (103), Expect = 3e-04
Identities = 63/272 (23%), Positives = 101/272 (37%), Gaps = 53/272 (19%)
Query: 212 QSHGPGQSDDACSEPTNKKMRRNRFKWGPASQQILYQAYDRQKNPSKEEREALVEECNRA 271
QS D P +K RR+R + + L +A++R P RE L +
Sbjct: 199 QSDEGSDIDSEPDLPLKRKQRRSRTTFTAEQLEELERAFERTHYPDIYTREELAQRAK-- 256
Query: 272 ECLQRGVSPSKAHGLGSNLVTEVRVYNWFANRRKEEAFRQKLAMDAYSSNQTHSLNPLLS 331
+TE RV WF+NRR +R++ +NQ + N L+
Sbjct: 257 -------------------LTEARVQVWFSNRRAR--WRKQA-----GANQLMAFNHLIP 290
Query: 332 HGSPHHQPSSSPPNKLSGVRYSQQGNNEITSSSTISHHGNSAMVTSQSVLQQVSPASLDP 391
G P + P +LS Y + S + + H + S +V Q P++ D
Sbjct: 291 GGFPPTAMPTLPTYQLSETSYQPTSIPQAVSDPSSTVHRPQPLPPS-TVHQSTIPSNPDS 349
Query: 392 G---------HNLLS----------PDGKMISVSGGGLPP--VSTLTNIHSLSHHNPQQS 430
H S P M G GL P + LTN H H PQ
Sbjct: 350 SSAYCLPSTRHGFSSYTDSFVPPSGPSNPMNPTIGNGLSPQVMGLLTN-HGGVPHQPQ-- 406
Query: 431 QNLIMTPLSGVMAIAQSLNTSQAQSVPVINSV 462
+ ++PL+G + +++ S +Q + + S+
Sbjct: 407 TDYALSPLTGGLEPTTTVSASCSQRLDHMKSL 438
>gi|31563344 paired box 3 isoform PAX3e [Homo sapiens]
Length = 505
Score = 44.3 bits (103), Expect = 3e-04
Identities = 63/272 (23%), Positives = 101/272 (37%), Gaps = 53/272 (19%)
Query: 212 QSHGPGQSDDACSEPTNKKMRRNRFKWGPASQQILYQAYDRQKNPSKEEREALVEECNRA 271
QS D P +K RR+R + + L +A++R P RE L +
Sbjct: 200 QSDEGSDIDSEPDLPLKRKQRRSRTTFTAEQLEELERAFERTHYPDIYTREELAQRAK-- 257
Query: 272 ECLQRGVSPSKAHGLGSNLVTEVRVYNWFANRRKEEAFRQKLAMDAYSSNQTHSLNPLLS 331
+TE RV WF+NRR +R++ +NQ + N L+
Sbjct: 258 -------------------LTEARVQVWFSNRRAR--WRKQA-----GANQLMAFNHLIP 291
Query: 332 HGSPHHQPSSSPPNKLSGVRYSQQGNNEITSSSTISHHGNSAMVTSQSVLQQVSPASLDP 391
G P + P +LS Y + S + + H + S +V Q P++ D
Sbjct: 292 GGFPPTAMPTLPTYQLSETSYQPTSIPQAVSDPSSTVHRPQPLPPS-TVHQSTIPSNPDS 350
Query: 392 G---------HNLLS----------PDGKMISVSGGGLPP--VSTLTNIHSLSHHNPQQS 430
H S P M G GL P + LTN H H PQ
Sbjct: 351 SSAYCLPSTRHGFSSYTDSFVPPSGPSNPMNPTIGNGLSPQVMGLLTN-HGGVPHQPQ-- 407
Query: 431 QNLIMTPLSGVMAIAQSLNTSQAQSVPVINSV 462
+ ++PL+G + +++ S +Q + + S+
Sbjct: 408 TDYALSPLTGGLEPTTTVSASCSQRLDHMKSL 439
>gi|31563342 paired box 3 isoform PAX3d [Homo sapiens]
Length = 484
Score = 44.3 bits (103), Expect = 3e-04
Identities = 63/272 (23%), Positives = 101/272 (37%), Gaps = 53/272 (19%)
Query: 212 QSHGPGQSDDACSEPTNKKMRRNRFKWGPASQQILYQAYDRQKNPSKEEREALVEECNRA 271
QS D P +K RR+R + + L +A++R P RE L +
Sbjct: 200 QSDEGSDIDSEPDLPLKRKQRRSRTTFTAEQLEELERAFERTHYPDIYTREELAQRAK-- 257
Query: 272 ECLQRGVSPSKAHGLGSNLVTEVRVYNWFANRRKEEAFRQKLAMDAYSSNQTHSLNPLLS 331
+TE RV WF+NRR +R++ +NQ + N L+
Sbjct: 258 -------------------LTEARVQVWFSNRRAR--WRKQA-----GANQLMAFNHLIP 291
Query: 332 HGSPHHQPSSSPPNKLSGVRYSQQGNNEITSSSTISHHGNSAMVTSQSVLQQVSPASLDP 391
G P + P +LS Y + S + + H + S +V Q P++ D
Sbjct: 292 GGFPPTAMPTLPTYQLSETSYQPTSIPQAVSDPSSTVHRPQPLPPS-TVHQSTIPSNPDS 350
Query: 392 G---------HNLLS----------PDGKMISVSGGGLPP--VSTLTNIHSLSHHNPQQS 430
H S P M G GL P + LTN H H PQ
Sbjct: 351 SSAYCLPSTRHGFSSYTDSFVPPSGPSNPMNPTIGNGLSPQVMGLLTN-HGGVPHQPQ-- 407
Query: 431 QNLIMTPLSGVMAIAQSLNTSQAQSVPVINSV 462
+ ++PL+G + +++ S +Q + + S+
Sbjct: 408 TDYALSPLTGGLEPTTTVSASCSQRLDHMKSL 439
>gi|31563340 paired box 3 isoform PAX3 [Homo sapiens]
Length = 479
Score = 44.3 bits (103), Expect = 3e-04
Identities = 63/272 (23%), Positives = 101/272 (37%), Gaps = 53/272 (19%)
Query: 212 QSHGPGQSDDACSEPTNKKMRRNRFKWGPASQQILYQAYDRQKNPSKEEREALVEECNRA 271
QS D P +K RR+R + + L +A++R P RE L +
Sbjct: 200 QSDEGSDIDSEPDLPLKRKQRRSRTTFTAEQLEELERAFERTHYPDIYTREELAQRAK-- 257
Query: 272 ECLQRGVSPSKAHGLGSNLVTEVRVYNWFANRRKEEAFRQKLAMDAYSSNQTHSLNPLLS 331
+TE RV WF+NRR +R++ +NQ + N L+
Sbjct: 258 -------------------LTEARVQVWFSNRRAR--WRKQA-----GANQLMAFNHLIP 291
Query: 332 HGSPHHQPSSSPPNKLSGVRYSQQGNNEITSSSTISHHGNSAMVTSQSVLQQVSPASLDP 391
G P + P +LS Y + S + + H + S +V Q P++ D
Sbjct: 292 GGFPPTAMPTLPTYQLSETSYQPTSIPQAVSDPSSTVHRPQPLPPS-TVHQSTIPSNPDS 350
Query: 392 G---------HNLLS----------PDGKMISVSGGGLPP--VSTLTNIHSLSHHNPQQS 430
H S P M G GL P + LTN H H PQ
Sbjct: 351 SSAYCLPSTRHGFSSYTDSFVPPSGPSNPMNPTIGNGLSPQVMGLLTN-HGGVPHQPQ-- 407
Query: 431 QNLIMTPLSGVMAIAQSLNTSQAQSVPVINSV 462
+ ++PL+G + +++ S +Q + + S+
Sbjct: 408 TDYALSPLTGGLEPTTTVSASCSQRLDHMKSL 439
>gi|19920317 cytoskeleton-associated protein 4 [Homo sapiens]
Length = 602
Score = 40.8 bits (94), Expect = 0.003
Identities = 61/264 (23%), Positives = 100/264 (37%), Gaps = 55/264 (20%)
Query: 225 EPTNKKMRRNRFKWGPASQQILYQAYDRQKNPSKEEREALVEECNRAECLQRGVSPSKAH 284
E + K + FK ++++ QA + S+E L EE R E R + S +H
Sbjct: 327 ELVSLKQEQQAFKEAADTERLALQALTEKLLRSEESVSRLPEEIRRLEEELRQLK-SDSH 385
Query: 285 GLGSNLVTEVRVYNWFANRRKEEAFRQK---------------LAMDAYSSNQTHSLNPL 329
G + F + EA +QK L+M S+ QT SL L
Sbjct: 386 GPKED--------GGFRHSEAFEALQQKSQGLDSRLQHVEDGVLSMQVASARQTESLESL 437
Query: 330 LSHGSPHHQPSSSPPNKLSGVRYSQQGNNEITSSSTISHHGNSAMVTSQSV--------- 380
LS H Q ++ +L G+ S+ + + +ST+ G + +V V
Sbjct: 438 LSKSQEHEQRLAALQGRLEGLGSSEADQDGL--ASTVRSLGETQLVLYGDVEELKRSVGE 495
Query: 381 -------LQQVSPASLDPGHNLLSPDGKMISVSGGGLPPVSTLTNIHSLSHHNPQQSQ-- 431
LQ+V + H LLS D LPP L + SL + SQ
Sbjct: 496 LPSTVESLQKVQ----EQVHTLLSQD----QAQAARLPPQDFLDRLSSLDNLKASVSQVE 547
Query: 432 ---NLIMTPLSGVMAIAQSLNTSQ 452
++ T + ++A + + T++
Sbjct: 548 ADLKMLRTAVDSLVAYSVKIETNE 571
>gi|157743257 POU domain, class 6, transcription factor 2 [Homo
sapiens]
Length = 691
Score = 40.8 bits (94), Expect = 0.003
Identities = 59/240 (24%), Positives = 98/240 (40%), Gaps = 29/240 (12%)
Query: 317 AYSSNQTHSLNPLLSHGSPHHQPSSSP----PNKLSGVRYSQQGNNEITSSSTISHHGNS 372
++S NQ +P SP +PS SP P+ L+ Q NN + S + + S
Sbjct: 255 SHSQNQNQP-SPTQQSSSPPQKPSQSPGHGLPSPLTPPNPLQLVNNPLASQAAAAAAAMS 313
Query: 373 AMVTSQSVLQQVSPASLDPGHNLLSPDGKMISVSGGGLPPVSTLTNIHSLSHHNPQQSQN 432
++ +SQ+ +S G + + G++I G P+ S + Q Q
Sbjct: 314 SIASSQAFGNALSSLQGVTGQLVTNAQGQII-----GTIPLMPNPGPSSQAASGTQGLQV 368
Query: 433 LIMTPLSGVMAIAQSLNTSQA-QSVPVINSVAGSLAALQPVQFSQQLHSPHQQPLMQQSP 491
+TP A Q + T Q +PVIN+ +L+ ++P QQLH P Q + Q
Sbjct: 369 QPITPQLLTNAQGQIIATVIGNQILPVINTQGITLSPIKP---GQQLHQPSQTSVGQ--- 422
Query: 492 GSHMAQQPFMAAVTQLQNSHMYAHKQEPPQYSHTSRFPSAMVVTDTSSISTLTNMSSSKQ 551
A +Q H+ AH Q S + S+ + +SS ++ + S+ Q
Sbjct: 423 -----------AASQGNLLHL-AHSQASMSQSPVRQASSSSSSSSSSSALSVGQLVSNPQ 470
>gi|171543895 ataxin 2 [Homo sapiens]
Length = 1313
Score = 39.7 bits (91), Expect = 0.007
Identities = 53/219 (24%), Positives = 77/219 (35%), Gaps = 41/219 (18%)
Query: 302 NRRKEEAFRQKLAMDAYSSNQTHSLNPLLSHGSPHHQPSSSPPNKLSGVRYSQQGNNEIT 361
N+ +F ++ + + H N L +PH QPS++P +G + SQ G +
Sbjct: 1113 NKETSPSFYFAISTGSLAQQYAHP-NATLHPHTPHPQPSATP----TGQQQSQHGGSHPA 1167
Query: 362 SSSTISHHGNSAMVTSQSVLQQVS----------PASLDPGHNLLSPDGKMISVSGGGLP 411
S H +A + QQ S P S+ P N SP +
Sbjct: 1168 PSPVQHHQHQAAQALHLASPQQQSAIYHAGLAPTPPSMTPASNTQSPQNSFPAAQ----- 1222
Query: 412 PVSTLTNIHSLSH------------HNPQQSQNLIMTPLSGVMAIAQSLNTSQAQSVPVI 459
T+ IH SH H PQ M P L T+Q P
Sbjct: 1223 --QTVFTIHP-SHVQPAYTNPPHMAHVPQAHVQSGMVPSHPTAHAPMMLMTTQPPGGP-- 1277
Query: 460 NSVAGSLAALQPVQFSQQLHSPHQQPLMQQSPGSHMAQQ 498
A + +ALQP+ S H P+ + S +H QQ
Sbjct: 1278 -QAALAQSALQPIPVSTTAHFPY---MTHPSVQAHHQQQ 1312
>gi|95147342 chromodomain helicase DNA binding protein 9 [Homo
sapiens]
Length = 2881
Score = 39.3 bits (90), Expect = 0.010
Identities = 30/100 (30%), Positives = 50/100 (50%), Gaps = 11/100 (11%)
Query: 318 YSSNQTHSLNPLLSHGSPH--HQPSSSPPNKLSGVRYSQQGNNEIT--SSSTISHH---- 369
+ NQ + L P +S GSP HQ +++ N+ +G + QQG++ + S ++HH
Sbjct: 106 HPQNQPNGLFPDVSDGSPMWGHQTATTISNQ-NGSPFHQQGHSHSMHQNKSFVAHHDFAL 164
Query: 370 --GNSAMVTSQSVLQQVSPASLDPGHNLLSPDGKMISVSG 407
N S+ Q + +L+PG N LS ++VSG
Sbjct: 165 FQANEQQTQCTSLRSQQNRNNLNPGQNSLSQSKNFMNVSG 204
>gi|167736355 mucin 4 isoform a [Homo sapiens]
Length = 5284
Score = 38.5 bits (88), Expect = 0.016
Identities = 58/235 (24%), Positives = 85/235 (36%), Gaps = 36/235 (15%)
Query: 319 SSNQTHSLNPLLSHGSPHHQPSSSPPNKLSGVRYSQQGNNEITSSSTISHHG-------- 370
S+ T SL + + +S P S V + +T +S++S
Sbjct: 1834 STGDTTSLPVTIPSSASSGHTTSLPVTDASSVSTGHATSLLVTDASSVSTGDTTPLPVTD 1893
Query: 371 -NSAMVTSQSVLQQVSPASLDPGHNLLSPDGKMISVSGGGLPPVSTLTNIHSLSHHNPQQ 429
NSA + L +S+ GH P + S S G P+ + + S H
Sbjct: 1894 TNSASTGDTTPLHVTDASSVSTGHATSLPVTSLSSASTGDTTPLPVTSPSSASSGHT--- 1950
Query: 430 SQNLIMTPLSGVMAIAQSLNTSQAQSVPV--INSVAGSLAALQPVQFSQQLHSPHQQPLM 487
TPL + A S+ T A S+PV +SV+ A PV + + + H PL
Sbjct: 1951 ------TPLP--VTDASSVPTGHATSLPVTDASSVSTGHATPLPVTDASSVSTGHATPLP 2002
Query: 488 QQSPGSHMAQQPFMAAVTQLQNSHMYAHKQEPPQYSHTSRFPSAMVVTDTSSIST 542
S Q VT L ++ T+ P VTDTSS ST
Sbjct: 2003 VTDTSSVSTGQATPLPVTSLSSA----------STGDTTPLP----VTDTSSAST 2043
Score = 34.3 bits (77), Expect = 0.31
Identities = 49/194 (25%), Positives = 74/194 (38%), Gaps = 36/194 (18%)
Query: 360 ITSSSTISH-HGNSAMVTSQSV--------LQQVSPASLDPGHNLLSPDGKMISVSGGGL 410
+T +S++S H S VT S L +S+ GH P + SVS G
Sbjct: 2723 VTDASSVSTGHATSLPVTDASSVSTGHATPLPVTDASSVSTGHATPLPLTSLSSVSTGDT 2782
Query: 411 PPVSTLTNIHSLSHHNPQQSQNLIMTPLSGVMAIAQSLNTSQAQSVPVINSVAGSL--AA 468
P+ + S + Q+ L +T LS S++T +PV ++ + S A
Sbjct: 2783 TPLP----VTDTSSASTGQATPLPVTSLS-------SVSTGDTTPLPVTDTSSASTGHAT 2831
Query: 469 LQPVQFSQQLHSPHQQPLMQQSPGSHMAQQPFMAAVTQLQNSHMYAHKQEPPQYSHTSRF 528
PV + + H PL S + VT ++ + H +
Sbjct: 2832 SLPVTDTSSASTGHATPLPDTDTSSASTGHATLLPVTDTSSASI----------GHATSL 2881
Query: 529 PSAMVVTDTSSIST 542
P VTDTSSIST
Sbjct: 2882 P----VTDTSSIST 2891
Score = 33.1 bits (74), Expect = 0.69
Identities = 50/202 (24%), Positives = 77/202 (38%), Gaps = 35/202 (17%)
Query: 371 NSAMVTSQSVLQQVSPASLDPGHNLLSPDGKMISVSGGGLPPVSTLTNIHSLSHHNPQQS 430
+SA + L SP+S GH P + S S G P+ + S S + +
Sbjct: 1287 SSASTGHVTPLHVTSPSSASTGHATPLPVTSLSSASTGDTMPLP----VTSPSSASTGDT 1342
Query: 431 QNLIMTPLSGV---------MAIAQSLNTSQAQSVPV--INSVAGSLAALQPVQFSQQLH 479
L +T S V + A S +T QA +PV ++SV+ PV
Sbjct: 1343 TPLPVTDASSVSTGHTTPLHVTDASSASTGQATPLPVTSLSSVSTGDTTPLPVTSPSSAS 1402
Query: 480 SPHQQPLMQQSPGS----HMAQQPFMAAVTQLQNSHMYAHKQEPPQYS---HTSRFP--- 529
+ H PL+ S H P A + + H + P + HT+ P
Sbjct: 1403 TGHATPLLVTDTSSASTGHATPLPVTDA-SSVSTDHATSLPVTIPSAASTGHTTPLPVTD 1461
Query: 530 ---------SAMVVTDTSSIST 542
++++VTDTSS+ST
Sbjct: 1462 TSSASTGQATSLLVTDTSSVST 1483
Score = 32.3 bits (72), Expect = 1.2
Identities = 47/186 (25%), Positives = 71/186 (38%), Gaps = 23/186 (12%)
Query: 361 TSSSTISHHGNSAMVTSQSVLQQVSPASLDPGHNLLSPDGKMISVSGGGLPPVSTLTNIH 420
++SS + H +VT S S+ GH P S S G P+ +
Sbjct: 3621 STSSASTGHATPLLVTDAS--------SVSTGHATPLPVTDASSASTGDTTPLP----VT 3668
Query: 421 SLSHHNPQQSQNLIMTPLSGVMAIAQSLNTSQAQSVPVINSVAGSL--AALQPVQFSQQL 478
S + Q+ L +T LS S++T +PV ++ + S A PV +
Sbjct: 3669 DTSSASTGQATPLPVTSLS-------SVSTGDTTPLPVTDASSASTGHATPLPVTIPSSV 3721
Query: 479 HSPHQQPLMQQSPGSHMAQQPFMAAVTQLQNSHMYAHKQEP--PQYSHTSRFPSAMVVTD 536
+ PL SP S VT L ++ P S ++R + + VTD
Sbjct: 3722 STGDTMPLPVTSPSSASTGHATPLPVTGLSSASTGDTTPLPVTDTSSASTRHATPLPVTD 3781
Query: 537 TSSIST 542
TSS ST
Sbjct: 3782 TSSAST 3787
Score = 30.4 bits (67), Expect = 4.5
Identities = 48/202 (23%), Positives = 75/202 (37%), Gaps = 35/202 (17%)
Query: 371 NSAMVTSQSVLQQVSPASLDPGHNLLSPDGKMISVSGGGLPPVSTLTNIHSLSHHNPQQS 430
+SA + L +S GH P SVS G P+ + + H +
Sbjct: 1079 SSASTGDTTPLPVTDTSSASTGHATSLPVTDTSSVSTGHTTPLPVTDTSSASTGH----A 1134
Query: 431 QNLIMTPLSGV---------MAIAQSLNTSQAQSVPV--INSVAGSLAALQPVQFSQQLH 479
+L +T S V + A S +T QA +PV ++SV+ PV
Sbjct: 1135 TSLPVTDTSSVSTGHTTPLHVTDASSASTGQATPLPVTSLSSVSTGDTTPLPVTSPSSAS 1194
Query: 480 SPHQQPLMQQSPGS----HMAQQPFMAAVTQLQNSHMYAHKQEPPQYS---HTSRFP--- 529
+ H PL+ S H P A + + H + P + HT+ P
Sbjct: 1195 TGHATPLLVTDTSSASTGHATPLPVTDA-SSVSTDHATSLPVTIPSAASTGHTTPLPVTD 1253
Query: 530 ---------SAMVVTDTSSIST 542
++++VTDTSS+ST
Sbjct: 1254 TSSASTGQATSLLVTDTSSVST 1275
>gi|31563348 paired box 3 isoform PAX3g [Homo sapiens]
Length = 403
Score = 38.1 bits (87), Expect = 0.021
Identities = 49/216 (22%), Positives = 76/216 (35%), Gaps = 38/216 (17%)
Query: 212 QSHGPGQSDDACSEPTNKKMRRNRFKWGPASQQILYQAYDRQKNPSKEEREALVEECNRA 271
QS D P +K RR+R + + L +A++R P RE L +
Sbjct: 200 QSDEGSDIDSEPDLPLKRKQRRSRTTFTAEQLEELERAFERTHYPDIYTREELAQRAK-- 257
Query: 272 ECLQRGVSPSKAHGLGSNLVTEVRVYNWFANRRKEEAFRQKLAMDAYSSNQTHSLNPLLS 331
+TE RV WF+NRR +R++ +NQ + N L+
Sbjct: 258 -------------------LTEARVQVWFSNRRAR--WRKQA-----GANQLMAFNHLIP 291
Query: 332 HGSPHHQPSSSPPNKLSGVRYSQQGNNEITSSSTISHHGNSAMVTSQSVLQQVSPASLDP 391
G P + P +LS Y + S + + H + S +V Q P++ D
Sbjct: 292 GGFPPTAMPTLPTYQLSETSYQPTSIPQAVSDPSSTVHRPQPLPPS-TVHQSTIPSNPDS 350
Query: 392 G---------HNLLSPDGKMISVSGGGLPPVSTLTN 418
H S + SG P T+ N
Sbjct: 351 SSAYCLPSTRHGFSSYTDSFVPPSGPSNPMNPTIGN 386
>gi|31563346 paired box 3 isoform PAX3h [Homo sapiens]
Length = 407
Score = 38.1 bits (87), Expect = 0.021
Identities = 49/216 (22%), Positives = 76/216 (35%), Gaps = 38/216 (17%)
Query: 212 QSHGPGQSDDACSEPTNKKMRRNRFKWGPASQQILYQAYDRQKNPSKEEREALVEECNRA 271
QS D P +K RR+R + + L +A++R P RE L +
Sbjct: 200 QSDEGSDIDSEPDLPLKRKQRRSRTTFTAEQLEELERAFERTHYPDIYTREELAQRAK-- 257
Query: 272 ECLQRGVSPSKAHGLGSNLVTEVRVYNWFANRRKEEAFRQKLAMDAYSSNQTHSLNPLLS 331
+TE RV WF+NRR +R++ +NQ + N L+
Sbjct: 258 -------------------LTEARVQVWFSNRRAR--WRKQA-----GANQLMAFNHLIP 291
Query: 332 HGSPHHQPSSSPPNKLSGVRYSQQGNNEITSSSTISHHGNSAMVTSQSVLQQVSPASLDP 391
G P + P +LS Y + S + + H + S +V Q P++ D
Sbjct: 292 GGFPPTAMPTLPTYQLSETSYQPTSIPQAVSDPSSTVHRPQPLPPS-TVHQSTIPSNPDS 350
Query: 392 G---------HNLLSPDGKMISVSGGGLPPVSTLTN 418
H S + SG P T+ N
Sbjct: 351 SSAYCLPSTRHGFSSYTDSFVPPSGPSNPMNPTIGN 386
>gi|157739945 tetratricopeptide repeat, ankyrin repeat and coiled-coil
containing 2 [Homo sapiens]
Length = 1990
Score = 37.7 bits (86), Expect = 0.028
Identities = 50/176 (28%), Positives = 74/176 (42%), Gaps = 26/176 (14%)
Query: 331 SHGSPHHQ-PSSSPPNKLSG-VRYSQQGNNEITSSSTISHHGNSAMVTSQSVLQQVSPAS 388
S G P Q P SSPP++ S + S G++++ + S G+ T QS +SP
Sbjct: 1434 SQGLPVIQSPPSSPPHRDSAYISSSPLGSHQVFDFRSSSSVGSPTRQTYQSTSPALSPTH 1493
Query: 389 LDPGHNLLSPDGKMISVSGGGL----PPVSTLTNIHSLSHHNPQQSQNLIMTPLSGVMAI 444
+ H SP + GG PPV Q + P S +
Sbjct: 1494 QN-SHYRPSPPHTSPAHQGGSYRFSPPPVGG-------------QGKEYPSPPPSPLRRG 1539
Query: 445 AQSLNTSQAQSVPVINSVAGSLAALQPVQFSQQLHSPHQQPLMQQSPGSHMAQQPF 500
Q + A+S+ V S +GS PV++ Q+ S Q P +SP S MAQ+P+
Sbjct: 1540 PQYRASPPAESMSVYRSQSGS-----PVRYQQET-SVSQLPGRPKSPLSKMAQRPY 1589
Score = 31.2 bits (69), Expect = 2.6
Identities = 23/74 (31%), Positives = 37/74 (50%), Gaps = 7/74 (9%)
Query: 325 SLNPLLSHGSPHHQP---SSSPPNKLSGVRYSQQGNN----EITSSSTISHHGNSAMVTS 377
S++ +LS SP + P S SPP+ +S + + + NN + S HG A +
Sbjct: 1872 SVDTVLSPTSPGNLPQPESFSPPSSISNIAFYNKTNNAQNGHLLEDDYYSPHGMLANGSR 1931
Query: 378 QSVLQQVSPASLDP 391
+L++VS AS P
Sbjct: 1932 GDLLERVSQASSYP 1945
>gi|119395716 forkhead box C1 [Homo sapiens]
Length = 553
Score = 37.0 bits (84), Expect = 0.048
Identities = 63/247 (25%), Positives = 90/247 (36%), Gaps = 39/247 (15%)
Query: 272 ECLQRGVSPSKAHGLGSNLVTEVRVYNWFANR---RKEEAFRQKLAM-DAYSSNQTHSLN 327
EC + K G GS + YN F N R+ F++K A+ D ++ H
Sbjct: 134 ECFVKVPRDDKKPGKGSYWTLDPDSYNMFENGSFLRRRRRFKKKDAVKDKEEKDRLHLKE 193
Query: 328 PLLSHGSPHHQPSSSPPNKLSGVRYSQQGNNEITSSSTISHHGNSAMVTSQSVLQQVSP- 386
P P QP +PP + G Q + + +G T S Q +SP
Sbjct: 194 P----PPPGRQPPPAPPEQADGNAPGPQ-PPPVRIQDIKTENG-----TCPSPPQPLSPA 243
Query: 387 ASLDPGH-----NLLSPDGKMISVSGGGLPPVSTLTNIHSLS------------------ 423
A+L G + SPD S+S G PP +L + LS
Sbjct: 244 AALGSGSAAAVPKIESPDSSSSSLSSGSSPP-GSLPSARPLSLDGADSAPPPPAPSAPPP 302
Query: 424 HHNPQQSQNLIMTPLSGVMAIAQSLNTSQAQSVPVINSVAGSLAALQPVQFSQQLHSPHQ 483
HH+ S + IMT L G A + +S + +S AG L +S S +
Sbjct: 303 HHSQGFSVDNIMTSLRGSPQSAAAELSSGLLASAAASSRAGIAPPLALGAYSPGQSSLYS 362
Query: 484 QPLMQQS 490
P Q S
Sbjct: 363 SPCSQTS 369
>gi|219275578 SIX homeobox 2 [Homo sapiens]
Length = 291
Score = 37.0 bits (84), Expect = 0.048
Identities = 49/201 (24%), Positives = 71/201 (35%), Gaps = 55/201 (27%)
Query: 242 SQQILYQAYDRQKNPSKEEREALVEECNRAECLQRGVSPSKAHGLGSNLVTEVRVYNWFA 301
S+ +L + Y PS E+ L E A GL T +V NWF
Sbjct: 135 SRSVLREWYAHNPYPSPREKRELAE----------------ATGL-----TTTQVSNWFK 173
Query: 302 NRRKEEAFRQKLAMDAYSSNQTHSLNPLLSHGSPHHQPSSSPPNKLSGVRYSQQGNNEIT 361
NRR+ + + + ++ ++S NPL SG +E T
Sbjct: 174 NRRQRDRAAEAKERENNENSNSNSHNPLNG----------------SGKSVLGSSEDEKT 217
Query: 362 SSSTISHHGNSAMVTSQSVLQQVSPASLDPGHNLLSPDGKM---ISVSGGGLPPVSTLTN 418
S T H +S ++L P L H+L P G + V GGG
Sbjct: 218 PSGTPDHSS-----SSPALLLSPPPPGLPSLHSLGHPPGPSAVPVPVPGGG--------G 264
Query: 419 IHSLSHHNPQQSQNLIMTPLS 439
L HH+ Q I+ P+S
Sbjct: 265 ADPLQHHHGLQDS--ILNPMS 283
>gi|5902024 paired mesoderm homeobox 1 isoform pmx-1a [Homo sapiens]
Length = 217
Score = 37.0 bits (84), Expect = 0.048
Identities = 34/139 (24%), Positives = 52/139 (37%), Gaps = 31/139 (22%)
Query: 207 PEFSQQSHGPGQSDDACS--EPTNKKMRRNRFKWGPASQQILYQAYDRQKNPSKEEREAL 264
P + S P Q +D + E +K RRNR + + Q L + ++R P RE L
Sbjct: 68 PGLTSGSDTPQQDNDQLNSEEKKKRKQRRNRTTFNSSQLQALERVFERTHYPDAFVREDL 127
Query: 265 VEECNRAECLQRGVSPSKAHGLGSNLVTEVRVYNWFANRRKE--------EAFRQKLAMD 316
N +TE RV WF NRR + A + +
Sbjct: 128 ARRVN---------------------LTEARVQVWFQNRRAKFRRNERAMLANKNASLLK 166
Query: 317 AYSSNQTHSLNPLLSHGSP 335
+YS + T P++ +P
Sbjct: 167 SYSGDVTAVEQPIVPRPAP 185
>gi|12707577 paired mesoderm homeobox 1 isoform pmx-1b [Homo
sapiens]
Length = 245
Score = 37.0 bits (84), Expect = 0.048
Identities = 34/139 (24%), Positives = 52/139 (37%), Gaps = 31/139 (22%)
Query: 207 PEFSQQSHGPGQSDDACS--EPTNKKMRRNRFKWGPASQQILYQAYDRQKNPSKEEREAL 264
P + S P Q +D + E +K RRNR + + Q L + ++R P RE L
Sbjct: 68 PGLTSGSDTPQQDNDQLNSEEKKKRKQRRNRTTFNSSQLQALERVFERTHYPDAFVREDL 127
Query: 265 VEECNRAECLQRGVSPSKAHGLGSNLVTEVRVYNWFANRRKE--------EAFRQKLAMD 316
N +TE RV WF NRR + A + +
Sbjct: 128 ARRVN---------------------LTEARVQVWFQNRRAKFRRNERAMLANKNASLLK 166
Query: 317 AYSSNQTHSLNPLLSHGSP 335
+YS + T P++ +P
Sbjct: 167 SYSGDVTAVEQPIVPRPAP 185
>gi|58530876 melanoma antigen family C, 1 [Homo sapiens]
Length = 1142
Score = 36.6 bits (83), Expect = 0.062
Identities = 70/249 (28%), Positives = 96/249 (38%), Gaps = 48/249 (19%)
Query: 334 SPHHQPSSSPPNKL--SGVRYSQQGNNEITSSSTISHHGNSAMVTSQSVLQQVSPASLDP 391
SP SSS P+ L S SQ S S + SQS LQ SP S
Sbjct: 627 SPVSICSSSTPSSLPQSFPESSQSPPEGPVQSPLHSPQSPPEGMHSQSPLQ--SPESAPE 684
Query: 392 GHNLLSPDGKMISVSGGGLPPVSTLTNIH----------SLSH-HNPQ---QSQNLIMTP 437
G + LSP + + L +L+++H SLS H PQ Q ++ +
Sbjct: 685 GEDSLSP----LQIPQSPLEGEDSLSSLHFPQSPPEWEDSLSPLHFPQFPPQGEDFQSSL 740
Query: 438 LSGVMAIAQSLNTSQAQSVPVINSVAGSLAALQPVQ----------FSQQLHSPHQQPLM 487
S V + S + S QS P A P+Q + L S H+ P
Sbjct: 741 QSPVSICSSSTSLSLPQSFPESPQSPPEGPAQSPLQRPVSSFFSYTLASLLQSSHESP-- 798
Query: 488 QQSPGSHMAQQPFMAAVTQLQNSHMYAHKQEPPQYSHTSRFPSAMVVTDTSSISTLTNMS 547
QSP AQ P + V+ +S + Q P S FPS + +SS+S
Sbjct: 799 -QSPPEGPAQSPLQSPVSSFPSSTSSSLSQSSP----VSSFPS----STSSSLS-----K 844
Query: 548 SSKQCPLQA 556
SS + PLQ+
Sbjct: 845 SSPESPLQS 853
>gi|209969838 transportin 2 (importin 3, karyopherin beta 2b)
isoform 1 [Homo sapiens]
Length = 897
Score = 36.2 bits (82), Expect = 0.081
Identities = 29/90 (32%), Positives = 38/90 (42%), Gaps = 13/90 (14%)
Query: 11 ELLSALLSSGVTKEVLVQALEELLPSPNFGVKLETLPLSPGSG----------AEPDTKP 60
E L + KEVL L +L+P G+K + + G +E D KP
Sbjct: 276 EFWLTLAEQPICKEVLASHLVQLIPILVNGMKYSEIDIILLKGDVEEDEAVPDSEQDIKP 335
Query: 61 VFH---TLTNGHAKGRLSGDEGSEDGDDYD 87
FH T+T H R G E +ED DD D
Sbjct: 336 RFHKSRTVTLPHEAERPDGSEDAEDDDDDD 365
>gi|209969836 transportin 2 (importin 3, karyopherin beta 2b)
isoform 3 [Homo sapiens]
Length = 887
Score = 36.2 bits (82), Expect = 0.081
Identities = 29/90 (32%), Positives = 38/90 (42%), Gaps = 13/90 (14%)
Query: 11 ELLSALLSSGVTKEVLVQALEELLPSPNFGVKLETLPLSPGSG----------AEPDTKP 60
E L + KEVL L +L+P G+K + + G +E D KP
Sbjct: 276 EFWLTLAEQPICKEVLASHLVQLIPILVNGMKYSEIDIILLKGDVEEDEAVPDSEQDIKP 335
Query: 61 VFH---TLTNGHAKGRLSGDEGSEDGDDYD 87
FH T+T H R G E +ED DD D
Sbjct: 336 RFHKSRTVTLPHEAERPDGSEDAEDDDDDD 365
>gi|48675813 transportin 2 (importin 3, karyopherin beta 2b) isoform
2 [Homo sapiens]
Length = 887
Score = 36.2 bits (82), Expect = 0.081
Identities = 29/90 (32%), Positives = 38/90 (42%), Gaps = 13/90 (14%)
Query: 11 ELLSALLSSGVTKEVLVQALEELLPSPNFGVKLETLPLSPGSG----------AEPDTKP 60
E L + KEVL L +L+P G+K + + G +E D KP
Sbjct: 276 EFWLTLAEQPICKEVLASHLVQLIPILVNGMKYSEIDIILLKGDVEEDEAVPDSEQDIKP 335
Query: 61 VFH---TLTNGHAKGRLSGDEGSEDGDDYD 87
FH T+T H R G E +ED DD D
Sbjct: 336 RFHKSRTVTLPHEAERPDGSEDAEDDDDDD 365
>gi|189083681 paired box gene 6 isoform a [Homo sapiens]
Length = 422
Score = 35.8 bits (81), Expect = 0.11
Identities = 56/262 (21%), Positives = 94/262 (35%), Gaps = 48/262 (18%)
Query: 211 QQSHGPGQSDDACSE------------PTNKKMRRNRFKWGPASQQILYQAYDRQKNPSK 258
QQ G G++ ++ S +K++RNR + + L + ++R P
Sbjct: 178 QQQEGGGENTNSISSNGEDSDEAQMRLQLKRKLQRNRTSFTQEQIEALEKEFERTHYPDV 237
Query: 259 EEREALVEECNRAECLQRGVSPSKAHGLGSNLVTEVRVYNWFANRRKEEAFRQKLAMDAY 318
RE L + + + E R+ WF+NRR + +KL
Sbjct: 238 FARERLAAKID---------------------LPEARIQVWFSNRRAKWRREEKLRNQRR 276
Query: 319 SSNQTHSLNPLLSHGSPH-HQPSSSPPNKLSGVRYSQQGNNEITSSSTISHHGNSAMVTS 377
++ T S P+ S S +QP P +S TS S + ++A+ +
Sbjct: 277 QASNTPSHIPISSSFSTSVYQPIPQPTTPVS----------SFTSGSMLG-RTDTALTNT 325
Query: 378 QSVLQQVSPASLDPGHNL-LSPDGKMISVSGGGLPPVSTLTNIHSLSHHNPQQSQNLIMT 436
S L + S +NL + P + S + P S N S + P Q + +
Sbjct: 326 YSALPPM--PSFTMANNLPMQPPVPSQTSSYSCMLPTSPSVNGRSYDTYTPPHMQTHMNS 383
Query: 437 PLSGVMAIAQSLNTSQAQSVPV 458
G + S SVPV
Sbjct: 384 QPMGTSGTTSTGLISPGVSVPV 405
>gi|4580424 paired box gene 6 isoform b [Homo sapiens]
Length = 436
Score = 35.8 bits (81), Expect = 0.11
Identities = 56/262 (21%), Positives = 94/262 (35%), Gaps = 48/262 (18%)
Query: 211 QQSHGPGQSDDACSE------------PTNKKMRRNRFKWGPASQQILYQAYDRQKNPSK 258
QQ G G++ ++ S +K++RNR + + L + ++R P
Sbjct: 192 QQQEGGGENTNSISSNGEDSDEAQMRLQLKRKLQRNRTSFTQEQIEALEKEFERTHYPDV 251
Query: 259 EEREALVEECNRAECLQRGVSPSKAHGLGSNLVTEVRVYNWFANRRKEEAFRQKLAMDAY 318
RE L + + + E R+ WF+NRR + +KL
Sbjct: 252 FARERLAAKID---------------------LPEARIQVWFSNRRAKWRREEKLRNQRR 290
Query: 319 SSNQTHSLNPLLSHGSPH-HQPSSSPPNKLSGVRYSQQGNNEITSSSTISHHGNSAMVTS 377
++ T S P+ S S +QP P +S TS S + ++A+ +
Sbjct: 291 QASNTPSHIPISSSFSTSVYQPIPQPTTPVS----------SFTSGSMLG-RTDTALTNT 339
Query: 378 QSVLQQVSPASLDPGHNL-LSPDGKMISVSGGGLPPVSTLTNIHSLSHHNPQQSQNLIMT 436
S L + S +NL + P + S + P S N S + P Q + +
Sbjct: 340 YSALPPM--PSFTMANNLPMQPPVPSQTSSYSCMLPTSPSVNGRSYDTYTPPHMQTHMNS 397
Query: 437 PLSGVMAIAQSLNTSQAQSVPV 458
G + S SVPV
Sbjct: 398 QPMGTSGTTSTGLISPGVSVPV 419
>gi|4505615 paired box gene 6 isoform a [Homo sapiens]
Length = 422
Score = 35.8 bits (81), Expect = 0.11
Identities = 56/262 (21%), Positives = 94/262 (35%), Gaps = 48/262 (18%)
Query: 211 QQSHGPGQSDDACSE------------PTNKKMRRNRFKWGPASQQILYQAYDRQKNPSK 258
QQ G G++ ++ S +K++RNR + + L + ++R P
Sbjct: 178 QQQEGGGENTNSISSNGEDSDEAQMRLQLKRKLQRNRTSFTQEQIEALEKEFERTHYPDV 237
Query: 259 EEREALVEECNRAECLQRGVSPSKAHGLGSNLVTEVRVYNWFANRRKEEAFRQKLAMDAY 318
RE L + + + E R+ WF+NRR + +KL
Sbjct: 238 FARERLAAKID---------------------LPEARIQVWFSNRRAKWRREEKLRNQRR 276
Query: 319 SSNQTHSLNPLLSHGSPH-HQPSSSPPNKLSGVRYSQQGNNEITSSSTISHHGNSAMVTS 377
++ T S P+ S S +QP P +S TS S + ++A+ +
Sbjct: 277 QASNTPSHIPISSSFSTSVYQPIPQPTTPVS----------SFTSGSMLG-RTDTALTNT 325
Query: 378 QSVLQQVSPASLDPGHNL-LSPDGKMISVSGGGLPPVSTLTNIHSLSHHNPQQSQNLIMT 436
S L + S +NL + P + S + P S N S + P Q + +
Sbjct: 326 YSALPPM--PSFTMANNLPMQPPVPSQTSSYSCMLPTSPSVNGRSYDTYTPPHMQTHMNS 383
Query: 437 PLSGVMAIAQSLNTSQAQSVPV 458
G + S SVPV
Sbjct: 384 QPMGTSGTTSTGLISPGVSVPV 405
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.310 0.124 0.355
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,297,976
Number of Sequences: 37866
Number of extensions: 1051852
Number of successful extensions: 3495
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 13
Number of HSP's successfully gapped in prelim test: 147
Number of HSP's that attempted gapping in prelim test: 3337
Number of HSP's gapped (non-prelim): 294
length of query: 557
length of database: 18,247,518
effective HSP length: 107
effective length of query: 450
effective length of database: 14,195,856
effective search space: 6388135200
effective search space used: 6388135200
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.