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Search of human proteins with 4507381
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4507381 thromboxane A2 receptor [Homo sapiens]
(343 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4507381 thromboxane A2 receptor [Homo sapiens] 684 0.0
gi|38505194 prostaglandin E receptor 1, subtype EP1 [Homo sapiens] 194 1e-49
gi|4506261 prostaglandin F receptor isoform a precursor [Homo sa... 189 3e-48
gi|89276764 prostaglandin E receptor 3, subtype EP3 isoform 2 [H... 179 4e-45
gi|38505186 prostaglandin E receptor 3, subtype EP3 isoform 8 [H... 178 5e-45
gi|38505180 prostaglandin E receptor 3, subtype EP3 isoform 5 [H... 177 1e-44
gi|38505188 prostaglandin E receptor 3, subtype EP3 isoform 4 [H... 177 1e-44
gi|38505184 prostaglandin E receptor 3, subtype EP3 isoform 7 [H... 177 1e-44
gi|38505182 prostaglandin E receptor 3, subtype EP3 isoform 6 [H... 177 1e-44
gi|38505178 prostaglandin E receptor 3, subtype EP3 isoform 4 [H... 177 1e-44
gi|38505176 prostaglandin E receptor 3, subtype EP3 isoform 3 [H... 177 1e-44
gi|38505172 prostaglandin E receptor 3, subtype EP3 isoform 1 [H... 177 1e-44
gi|186659506 prostaglandin E receptor 3, subtype EP3 isoform 4 [... 177 1e-44
gi|88758606 prostaglandin F receptor isoform b precursor [Homo s... 147 1e-35
gi|4506263 prostaglandin I2 (prostacyclin) receptor (IP) [Homo s... 130 2e-30
gi|4506259 prostaglandin E receptor 4, subtype EP4 [Homo sapiens] 115 6e-26
gi|31881630 prostaglandin E receptor 2 (subtype EP2), 53kDa [Hom... 114 2e-25
gi|28466969 prostaglandin D2 receptor [Homo sapiens] 104 1e-22
gi|9506745 urotensin 2 receptor [Homo sapiens] 60 2e-09
gi|15150803 opsin 4 isoform 1 [Homo sapiens] 59 8e-09
gi|71999143 opsin 4 isoform 2 [Homo sapiens] 57 2e-08
gi|4885325 G protein-coupled receptor 3 [Homo sapiens] 55 9e-08
gi|4557859 somatostatin receptor 2 [Homo sapiens] 54 2e-07
gi|148228791 G protein-coupled receptor 30 [Homo sapiens] 54 3e-07
gi|91106714 G protein-coupled receptor 30 [Homo sapiens] 54 3e-07
gi|4504091 G protein-coupled receptor 30 [Homo sapiens] 54 3e-07
gi|4501957 alpha-1D-adrenergic receptor [Homo sapiens] 53 5e-07
gi|64085121 thyroid stimulating hormone receptor isoform 1 precu... 52 8e-07
gi|23463303 purinergic receptor P2Y11 [Homo sapiens] 52 8e-07
gi|99028871 PPAN-P2RY11 protein [Homo sapiens] 52 8e-07
>gi|4507381 thromboxane A2 receptor [Homo sapiens]
Length = 343
Score = 684 bits (1765), Expect = 0.0
Identities = 343/343 (100%), Positives = 343/343 (100%)
Query: 1 MWPNGSSLGPCFRPTNITLEERRLIASPWFAASFCVVGLASNLLALSVLAGARQGGSHTR 60
MWPNGSSLGPCFRPTNITLEERRLIASPWFAASFCVVGLASNLLALSVLAGARQGGSHTR
Sbjct: 1 MWPNGSSLGPCFRPTNITLEERRLIASPWFAASFCVVGLASNLLALSVLAGARQGGSHTR 60
Query: 61 SSFLTFLCGLVLTDFLGLLVTGTIVVSQHAALFEWHAVDPGCRLCRFMGVVMIFFGLSPL 120
SSFLTFLCGLVLTDFLGLLVTGTIVVSQHAALFEWHAVDPGCRLCRFMGVVMIFFGLSPL
Sbjct: 61 SSFLTFLCGLVLTDFLGLLVTGTIVVSQHAALFEWHAVDPGCRLCRFMGVVMIFFGLSPL 120
Query: 121 LLGAAMASERYLGITRPFSRPAVASQRRAWATVGLVWAAALALGLLPLLGVGRYTVQYPG 180
LLGAAMASERYLGITRPFSRPAVASQRRAWATVGLVWAAALALGLLPLLGVGRYTVQYPG
Sbjct: 121 LLGAAMASERYLGITRPFSRPAVASQRRAWATVGLVWAAALALGLLPLLGVGRYTVQYPG 180
Query: 181 SWCFLTLGAESGDVAFGLLFSMLGGLSVGLSFLLNTVSVATLCHVYHGQEAAQQRPRDSE 240
SWCFLTLGAESGDVAFGLLFSMLGGLSVGLSFLLNTVSVATLCHVYHGQEAAQQRPRDSE
Sbjct: 181 SWCFLTLGAESGDVAFGLLFSMLGGLSVGLSFLLNTVSVATLCHVYHGQEAAQQRPRDSE 240
Query: 241 VEMMAQLLGIMVVASVCWLPLLVFIAQTVLRNPPAMSPAGQLSRTTEKELLIYLRVATWN 300
VEMMAQLLGIMVVASVCWLPLLVFIAQTVLRNPPAMSPAGQLSRTTEKELLIYLRVATWN
Sbjct: 241 VEMMAQLLGIMVVASVCWLPLLVFIAQTVLRNPPAMSPAGQLSRTTEKELLIYLRVATWN 300
Query: 301 QILDPWVYILFRRAVLRRLQPRLSTRPRSLSLQPQLTQRSGLQ 343
QILDPWVYILFRRAVLRRLQPRLSTRPRSLSLQPQLTQRSGLQ
Sbjct: 301 QILDPWVYILFRRAVLRRLQPRLSTRPRSLSLQPQLTQRSGLQ 343
>gi|38505194 prostaglandin E receptor 1, subtype EP1 [Homo sapiens]
Length = 402
Score = 194 bits (492), Expect = 1e-49
Identities = 141/407 (34%), Positives = 195/407 (47%), Gaps = 86/407 (21%)
Query: 8 LGPCFRPTNITLE-ERRLIASPWFAASFCV---------------VGLASNLLALSVLAG 51
+ PC P N++L E A+PW + V +G SNLLAL++LA
Sbjct: 1 MSPC-GPLNLSLAGEATTCAAPWVPNTSAVPPSGASPALPIFSMTLGAVSNLLALALLAQ 59
Query: 52 A--RQGGSHTRSSFLTFLCGLVLTDFLGLLVTGTIVVSQHAALFEWHAVDPGCRLCRFMG 109
A R + ++FL F+ L+ TD G ++ G +V+ + A P C F+G
Sbjct: 60 AAGRLRRRRSAATFLLFVASLLATDLAGHVIPGALVLRLYTA-----GRAPAGGACHFLG 114
Query: 110 VVMIFFGLSPLLLGAAMASERYLGITRPFSRPAVASQRRAWATVGLVWAAALALGLLPLL 169
M+FFGL PLLLG MA ER +G+TRP A S RA + V A ALA+ LLPL
Sbjct: 115 GCMVFFGLCPLLLGCGMAVERCVGVTRPLLHAARVSVARARLALAAVAAVALAVALLPLA 174
Query: 170 GVGRYTVQYPGSWCFLTLGAESG--DVAFGLLFSMLGGLSVGLSFLLNTVSVATLCHV-- 225
VGRY +QYPG+WCF+ LG G LF+ LG +++ + + NT+S L
Sbjct: 175 RVGRYELQYPGTWCFIGLGPPGGWRQALLAGLFASLGLVALLAALVCNTLSGLALLRARW 234
Query: 226 --------------------YHGQEAAQ-----------------------QRPRDSEVE 242
HG +A +R R +VE
Sbjct: 235 RRRSRRPPPASGPDSRRRWGAHGPRSASASSASSIASASTFFGGSRSSGSARRARAHDVE 294
Query: 243 MMAQLLGIMVVASVCWLPLLVFIAQTVLRNPPAMSPAGQLSRTTEKELLIYLRVATWNQI 302
M+ QL+GIMVV+ +CW P+LV +A V G S + ++ L + +R+A+WNQI
Sbjct: 295 MVGQLVGIMVVSCICWSPMLVLVALAV---------GGWSSTSLQRPLFLAVRLASWNQI 345
Query: 303 LDPWVYILFRRAVLRRLQPRLSTR------PRSLSLQPQLTQRSGLQ 343
LDPWVYIL R+AVLR+L L R P L L P + S L+
Sbjct: 346 LDPWVYILLRQAVLRQLLRLLPPRAGAKGGPAGLGLTPSAWEASSLR 392
>gi|4506261 prostaglandin F receptor isoform a precursor [Homo
sapiens]
Length = 359
Score = 189 bits (480), Expect = 3e-48
Identities = 120/302 (39%), Positives = 166/302 (54%), Gaps = 14/302 (4%)
Query: 21 ERRLIASPWFAASFCVVGLASNLLALSVLAGARQG-GSHTRSSFLTFLCGLVLTDFLGLL 79
E RL S +F+ F VG+ SN LA+++L A Q +++SFL GLV+TDF G L
Sbjct: 25 ENRL--SVFFSVIFMTVGILSNSLAIAILMKAYQRFRQKSKASFLLLASGLVITDFFGHL 82
Query: 80 VTGTIVVSQHAALFEWHAVDPGCRLCRFMGVVMIFFGLSPLLLGAAMASERYLGITRPFS 139
+ G I V +A+ EW D LC G+ M+F GL PLLLG+ MA ER +G+T+P
Sbjct: 83 INGAIAVFVYASDKEWIRFDQSNVLCSIFGICMVFSGLCPLLLGSVMAIERCIGVTKPIF 142
Query: 140 RPAVASQRRAWATVGLVWAAALALGLLPLLGVGRYTVQYPGSWCFLTLG--AESGDVAFG 197
+ + + V A+ + LLP+LG Y +Q +WCF + D +
Sbjct: 143 HSTKITSKHVKMMLSGVCLFAVFIALLPILGHRDYKIQASRTWCFYNTEDIKDWEDRFYL 202
Query: 198 LLFSMLGGLSVGLSFLLNTVSVATLCHVYHGQEAAQQRPRDSEVEMMAQLLGIMVVASVC 257
LLFS LG L++G+S L N ++ TL V + +Q R +EM+ QLL IM V+ +C
Sbjct: 203 LLFSFLGLLALGVSLLCNAITGITLLRVKFKSQQHRQ-GRSHHLEMVIQLLAIMCVSCIC 261
Query: 258 WLPLLVFIAQTVLRNPPAMSPAGQLSRTTEKELLIYLRVATWNQILDPWVYILFRRAVLR 317
W P LV +A + G S T + L LR+ATWNQILDPWVYIL R+AVL+
Sbjct: 262 WSPFLVTMANIGIN--------GNHSLETCETTLFALRMATWNQILDPWVYILLRKAVLK 313
Query: 318 RL 319
L
Sbjct: 314 NL 315
>gi|89276764 prostaglandin E receptor 3, subtype EP3 isoform 2 [Homo
sapiens]
Length = 402
Score = 179 bits (453), Expect = 4e-45
Identities = 112/323 (34%), Positives = 165/323 (51%), Gaps = 22/323 (6%)
Query: 30 FAASFCVVGLASNLLALSVLAGA-RQGGSHTRSSFLTFLCGLVLTDFLGLLVTGTIVVSQ 88
F + + G N LA+ +++ + R+ S + SFL + L LTD +G L+T +V+
Sbjct: 54 FPITMLLTGFVGNALAMLLVSRSYRRRESKRKKSFLLCIGWLALTDLVGQLLTTPVVIVV 113
Query: 89 HAALFEWHAVDPGCRLCRFMGVVMIFFGLSPLLLGAAMASERYLGITRPFSRPAVASQRR 148
+ + W +DP RLC F G+ M FGLS L + +AMA ER L I P + R
Sbjct: 114 YLSKQRWEHIDPSGRLCTFFGLTMTVFGLSSLFIASAMAVERALAIRAPHWYASHMKTRA 173
Query: 149 AWATVGLVWAAALALGLLPLLGVGRYTVQYPGSWCFLTLGAES---------GDVAFGLL 199
A + VW A LA LLP+LGVG+YTVQ+PG+WCF++ G G++ F
Sbjct: 174 TRAVLLGVWLAVLAFALLPVLGVGQYTVQWPGTWCFISTGRGGNGTSSSHNWGNLFFASA 233
Query: 200 FSMLGGLSVGLSFLLNTVSVATLCHVYHGQEAAQQRPRD---SEVEMMAQLLGIMVVASV 256
F+ LG L++ ++F N ++ L + A Q E QL+GIM V SV
Sbjct: 234 FAFLGLLALTVTFSCNLATIKALVSRCRAKATASQSSAQWGRITTETAIQLMGIMCVLSV 293
Query: 257 CWLPLLVFIAQTVLRNPPAMSPAGQLSRTTEKE-----LLIYLRVATWNQILDPWVYILF 311
CW PLL+ + + + + TEK+ LI +R+A+ NQILDPWVY+L
Sbjct: 294 CWSPLLIMMLKMIFN----QTSVEHCKTHTEKQKECNFFLIAVRLASLNQILDPWVYLLL 349
Query: 312 RRAVLRRLQPRLSTRPRSLSLQP 334
R+ +LR+ R R + P
Sbjct: 350 RKILLRKFCQMRKRRLREQEMGP 372
>gi|38505186 prostaglandin E receptor 3, subtype EP3 isoform 8 [Homo
sapiens]
Length = 418
Score = 178 bits (452), Expect = 5e-45
Identities = 116/332 (34%), Positives = 169/332 (50%), Gaps = 25/332 (7%)
Query: 30 FAASFCVVGLASNLLALSVLAGA-RQGGSHTRSSFLTFLCGLVLTDFLGLLVTGTIVVSQ 88
F + + G N LA+ +++ + R+ S + SFL + L LTD +G L+T +V+
Sbjct: 54 FPITMLLTGFVGNALAMLLVSRSYRRRESKRKKSFLLCIGWLALTDLVGQLLTTPVVIVV 113
Query: 89 HAALFEWHAVDPGCRLCRFMGVVMIFFGLSPLLLGAAMASERYLGITRPFSRPAVASQRR 148
+ + W +DP RLC F G+ M FGLS L + +AMA ER L I P + R
Sbjct: 114 YLSKQRWEHIDPSGRLCTFFGLTMTVFGLSSLFIASAMAVERALAIRAPHWYASHMKTRA 173
Query: 149 AWATVGLVWAAALALGLLPLLGVGRYTVQYPGSWCFLTLGAES---------GDVAFGLL 199
A + VW A LA LLP+LGVG+YTVQ+PG+WCF++ G G++ F
Sbjct: 174 TRAVLLGVWLAVLAFALLPVLGVGQYTVQWPGTWCFISTGRGGNGTSSSHNWGNLFFASA 233
Query: 200 FSMLGGLSVGLSFLLNTVSVATLCHVYHGQEAAQQRPRD---SEVEMMAQLLGIMVVASV 256
F+ LG L++ ++F N ++ L + A Q E QL+GIM V SV
Sbjct: 234 FAFLGLLALTVTFSCNLATIKALVSRCRAKATASQSSAQWGRITTETAIQLMGIMCVLSV 293
Query: 257 CWLPLLVFIAQTVLRNPPAMSPAGQLSRTTEKE-----LLIYLRVATWNQILDPWVYILF 311
CW PLL+ + + + + TEK+ LI +R+A+ NQILDPWVY+L
Sbjct: 294 CWSPLLIMMLKMIFN----QTSVEHCKTHTEKQKECNFFLIAVRLASLNQILDPWVYLLL 349
Query: 312 RRAVLRRLQPRLSTRPRS---LSLQPQLTQRS 340
R+ +LR+ R R SLQ QR+
Sbjct: 350 RKILLRKFCQMRKRRLREQLICSLQNSQIQRA 381
>gi|38505180 prostaglandin E receptor 3, subtype EP3 isoform 5 [Homo
sapiens]
Length = 388
Score = 177 bits (449), Expect = 1e-44
Identities = 109/307 (35%), Positives = 161/307 (52%), Gaps = 22/307 (7%)
Query: 30 FAASFCVVGLASNLLALSVLAGA-RQGGSHTRSSFLTFLCGLVLTDFLGLLVTGTIVVSQ 88
F + + G N LA+ +++ + R+ S + SFL + L LTD +G L+T +V+
Sbjct: 54 FPITMLLTGFVGNALAMLLVSRSYRRRESKRKKSFLLCIGWLALTDLVGQLLTTPVVIVV 113
Query: 89 HAALFEWHAVDPGCRLCRFMGVVMIFFGLSPLLLGAAMASERYLGITRPFSRPAVASQRR 148
+ + W +DP RLC F G+ M FGLS L + +AMA ER L I P + R
Sbjct: 114 YLSKQRWEHIDPSGRLCTFFGLTMTVFGLSSLFIASAMAVERALAIRAPHWYASHMKTRA 173
Query: 149 AWATVGLVWAAALALGLLPLLGVGRYTVQYPGSWCFLTLGAES---------GDVAFGLL 199
A + VW A LA LLP+LGVG+YTVQ+PG+WCF++ G G++ F
Sbjct: 174 TRAVLLGVWLAVLAFALLPVLGVGQYTVQWPGTWCFISTGRGGNGTSSSHNWGNLFFASA 233
Query: 200 FSMLGGLSVGLSFLLNTVSVATLCHVYHGQEAAQQRPRD---SEVEMMAQLLGIMVVASV 256
F+ LG L++ ++F N ++ L + A Q E QL+GIM V SV
Sbjct: 234 FAFLGLLALTVTFSCNLATIKALVSRCRAKATASQSSAQWGRITTETAIQLMGIMCVLSV 293
Query: 257 CWLPLLVFIAQTVLRNPPAMSPAGQLSRTTEKE-----LLIYLRVATWNQILDPWVYILF 311
CW PLL+ + + + + TEK+ LI +R+A+ NQILDPWVY+L
Sbjct: 294 CWSPLLIMMLKMIFN----QTSVEHCKTHTEKQKECNFFLIAVRLASLNQILDPWVYLLL 349
Query: 312 RRAVLRR 318
R+ +LR+
Sbjct: 350 RKILLRK 356
>gi|38505188 prostaglandin E receptor 3, subtype EP3 isoform 4 [Homo
sapiens]
Length = 390
Score = 177 bits (449), Expect = 1e-44
Identities = 109/307 (35%), Positives = 161/307 (52%), Gaps = 22/307 (7%)
Query: 30 FAASFCVVGLASNLLALSVLAGA-RQGGSHTRSSFLTFLCGLVLTDFLGLLVTGTIVVSQ 88
F + + G N LA+ +++ + R+ S + SFL + L LTD +G L+T +V+
Sbjct: 54 FPITMLLTGFVGNALAMLLVSRSYRRRESKRKKSFLLCIGWLALTDLVGQLLTTPVVIVV 113
Query: 89 HAALFEWHAVDPGCRLCRFMGVVMIFFGLSPLLLGAAMASERYLGITRPFSRPAVASQRR 148
+ + W +DP RLC F G+ M FGLS L + +AMA ER L I P + R
Sbjct: 114 YLSKQRWEHIDPSGRLCTFFGLTMTVFGLSSLFIASAMAVERALAIRAPHWYASHMKTRA 173
Query: 149 AWATVGLVWAAALALGLLPLLGVGRYTVQYPGSWCFLTLGAES---------GDVAFGLL 199
A + VW A LA LLP+LGVG+YTVQ+PG+WCF++ G G++ F
Sbjct: 174 TRAVLLGVWLAVLAFALLPVLGVGQYTVQWPGTWCFISTGRGGNGTSSSHNWGNLFFASA 233
Query: 200 FSMLGGLSVGLSFLLNTVSVATLCHVYHGQEAAQQRPRD---SEVEMMAQLLGIMVVASV 256
F+ LG L++ ++F N ++ L + A Q E QL+GIM V SV
Sbjct: 234 FAFLGLLALTVTFSCNLATIKALVSRCRAKATASQSSAQWGRITTETAIQLMGIMCVLSV 293
Query: 257 CWLPLLVFIAQTVLRNPPAMSPAGQLSRTTEKE-----LLIYLRVATWNQILDPWVYILF 311
CW PLL+ + + + + TEK+ LI +R+A+ NQILDPWVY+L
Sbjct: 294 CWSPLLIMMLKMIFN----QTSVEHCKTHTEKQKECNFFLIAVRLASLNQILDPWVYLLL 349
Query: 312 RRAVLRR 318
R+ +LR+
Sbjct: 350 RKILLRK 356
>gi|38505184 prostaglandin E receptor 3, subtype EP3 isoform 7 [Homo
sapiens]
Length = 365
Score = 177 bits (449), Expect = 1e-44
Identities = 109/307 (35%), Positives = 161/307 (52%), Gaps = 22/307 (7%)
Query: 30 FAASFCVVGLASNLLALSVLAGA-RQGGSHTRSSFLTFLCGLVLTDFLGLLVTGTIVVSQ 88
F + + G N LA+ +++ + R+ S + SFL + L LTD +G L+T +V+
Sbjct: 54 FPITMLLTGFVGNALAMLLVSRSYRRRESKRKKSFLLCIGWLALTDLVGQLLTTPVVIVV 113
Query: 89 HAALFEWHAVDPGCRLCRFMGVVMIFFGLSPLLLGAAMASERYLGITRPFSRPAVASQRR 148
+ + W +DP RLC F G+ M FGLS L + +AMA ER L I P + R
Sbjct: 114 YLSKQRWEHIDPSGRLCTFFGLTMTVFGLSSLFIASAMAVERALAIRAPHWYASHMKTRA 173
Query: 149 AWATVGLVWAAALALGLLPLLGVGRYTVQYPGSWCFLTLGAES---------GDVAFGLL 199
A + VW A LA LLP+LGVG+YTVQ+PG+WCF++ G G++ F
Sbjct: 174 TRAVLLGVWLAVLAFALLPVLGVGQYTVQWPGTWCFISTGRGGNGTSSSHNWGNLFFASA 233
Query: 200 FSMLGGLSVGLSFLLNTVSVATLCHVYHGQEAAQQRPRD---SEVEMMAQLLGIMVVASV 256
F+ LG L++ ++F N ++ L + A Q E QL+GIM V SV
Sbjct: 234 FAFLGLLALTVTFSCNLATIKALVSRCRAKATASQSSAQWGRITTETAIQLMGIMCVLSV 293
Query: 257 CWLPLLVFIAQTVLRNPPAMSPAGQLSRTTEKE-----LLIYLRVATWNQILDPWVYILF 311
CW PLL+ + + + + TEK+ LI +R+A+ NQILDPWVY+L
Sbjct: 294 CWSPLLIMMLKMIFN----QTSVEHCKTHTEKQKECNFFLIAVRLASLNQILDPWVYLLL 349
Query: 312 RRAVLRR 318
R+ +LR+
Sbjct: 350 RKILLRK 356
>gi|38505182 prostaglandin E receptor 3, subtype EP3 isoform 6 [Homo
sapiens]
Length = 374
Score = 177 bits (449), Expect = 1e-44
Identities = 109/307 (35%), Positives = 161/307 (52%), Gaps = 22/307 (7%)
Query: 30 FAASFCVVGLASNLLALSVLAGA-RQGGSHTRSSFLTFLCGLVLTDFLGLLVTGTIVVSQ 88
F + + G N LA+ +++ + R+ S + SFL + L LTD +G L+T +V+
Sbjct: 54 FPITMLLTGFVGNALAMLLVSRSYRRRESKRKKSFLLCIGWLALTDLVGQLLTTPVVIVV 113
Query: 89 HAALFEWHAVDPGCRLCRFMGVVMIFFGLSPLLLGAAMASERYLGITRPFSRPAVASQRR 148
+ + W +DP RLC F G+ M FGLS L + +AMA ER L I P + R
Sbjct: 114 YLSKQRWEHIDPSGRLCTFFGLTMTVFGLSSLFIASAMAVERALAIRAPHWYASHMKTRA 173
Query: 149 AWATVGLVWAAALALGLLPLLGVGRYTVQYPGSWCFLTLGAES---------GDVAFGLL 199
A + VW A LA LLP+LGVG+YTVQ+PG+WCF++ G G++ F
Sbjct: 174 TRAVLLGVWLAVLAFALLPVLGVGQYTVQWPGTWCFISTGRGGNGTSSSHNWGNLFFASA 233
Query: 200 FSMLGGLSVGLSFLLNTVSVATLCHVYHGQEAAQQRPRD---SEVEMMAQLLGIMVVASV 256
F+ LG L++ ++F N ++ L + A Q E QL+GIM V SV
Sbjct: 234 FAFLGLLALTVTFSCNLATIKALVSRCRAKATASQSSAQWGRITTETAIQLMGIMCVLSV 293
Query: 257 CWLPLLVFIAQTVLRNPPAMSPAGQLSRTTEKE-----LLIYLRVATWNQILDPWVYILF 311
CW PLL+ + + + + TEK+ LI +R+A+ NQILDPWVY+L
Sbjct: 294 CWSPLLIMMLKMIFN----QTSVEHCKTHTEKQKECNFFLIAVRLASLNQILDPWVYLLL 349
Query: 312 RRAVLRR 318
R+ +LR+
Sbjct: 350 RKILLRK 356
>gi|38505178 prostaglandin E receptor 3, subtype EP3 isoform 4 [Homo
sapiens]
Length = 390
Score = 177 bits (449), Expect = 1e-44
Identities = 109/307 (35%), Positives = 161/307 (52%), Gaps = 22/307 (7%)
Query: 30 FAASFCVVGLASNLLALSVLAGA-RQGGSHTRSSFLTFLCGLVLTDFLGLLVTGTIVVSQ 88
F + + G N LA+ +++ + R+ S + SFL + L LTD +G L+T +V+
Sbjct: 54 FPITMLLTGFVGNALAMLLVSRSYRRRESKRKKSFLLCIGWLALTDLVGQLLTTPVVIVV 113
Query: 89 HAALFEWHAVDPGCRLCRFMGVVMIFFGLSPLLLGAAMASERYLGITRPFSRPAVASQRR 148
+ + W +DP RLC F G+ M FGLS L + +AMA ER L I P + R
Sbjct: 114 YLSKQRWEHIDPSGRLCTFFGLTMTVFGLSSLFIASAMAVERALAIRAPHWYASHMKTRA 173
Query: 149 AWATVGLVWAAALALGLLPLLGVGRYTVQYPGSWCFLTLGAES---------GDVAFGLL 199
A + VW A LA LLP+LGVG+YTVQ+PG+WCF++ G G++ F
Sbjct: 174 TRAVLLGVWLAVLAFALLPVLGVGQYTVQWPGTWCFISTGRGGNGTSSSHNWGNLFFASA 233
Query: 200 FSMLGGLSVGLSFLLNTVSVATLCHVYHGQEAAQQRPRD---SEVEMMAQLLGIMVVASV 256
F+ LG L++ ++F N ++ L + A Q E QL+GIM V SV
Sbjct: 234 FAFLGLLALTVTFSCNLATIKALVSRCRAKATASQSSAQWGRITTETAIQLMGIMCVLSV 293
Query: 257 CWLPLLVFIAQTVLRNPPAMSPAGQLSRTTEKE-----LLIYLRVATWNQILDPWVYILF 311
CW PLL+ + + + + TEK+ LI +R+A+ NQILDPWVY+L
Sbjct: 294 CWSPLLIMMLKMIFN----QTSVEHCKTHTEKQKECNFFLIAVRLASLNQILDPWVYLLL 349
Query: 312 RRAVLRR 318
R+ +LR+
Sbjct: 350 RKILLRK 356
>gi|38505176 prostaglandin E receptor 3, subtype EP3 isoform 3 [Homo
sapiens]
Length = 393
Score = 177 bits (449), Expect = 1e-44
Identities = 109/307 (35%), Positives = 161/307 (52%), Gaps = 22/307 (7%)
Query: 30 FAASFCVVGLASNLLALSVLAGA-RQGGSHTRSSFLTFLCGLVLTDFLGLLVTGTIVVSQ 88
F + + G N LA+ +++ + R+ S + SFL + L LTD +G L+T +V+
Sbjct: 54 FPITMLLTGFVGNALAMLLVSRSYRRRESKRKKSFLLCIGWLALTDLVGQLLTTPVVIVV 113
Query: 89 HAALFEWHAVDPGCRLCRFMGVVMIFFGLSPLLLGAAMASERYLGITRPFSRPAVASQRR 148
+ + W +DP RLC F G+ M FGLS L + +AMA ER L I P + R
Sbjct: 114 YLSKQRWEHIDPSGRLCTFFGLTMTVFGLSSLFIASAMAVERALAIRAPHWYASHMKTRA 173
Query: 149 AWATVGLVWAAALALGLLPLLGVGRYTVQYPGSWCFLTLGAES---------GDVAFGLL 199
A + VW A LA LLP+LGVG+YTVQ+PG+WCF++ G G++ F
Sbjct: 174 TRAVLLGVWLAVLAFALLPVLGVGQYTVQWPGTWCFISTGRGGNGTSSSHNWGNLFFASA 233
Query: 200 FSMLGGLSVGLSFLLNTVSVATLCHVYHGQEAAQQRPRD---SEVEMMAQLLGIMVVASV 256
F+ LG L++ ++F N ++ L + A Q E QL+GIM V SV
Sbjct: 234 FAFLGLLALTVTFSCNLATIKALVSRCRAKATASQSSAQWGRITTETAIQLMGIMCVLSV 293
Query: 257 CWLPLLVFIAQTVLRNPPAMSPAGQLSRTTEKE-----LLIYLRVATWNQILDPWVYILF 311
CW PLL+ + + + + TEK+ LI +R+A+ NQILDPWVY+L
Sbjct: 294 CWSPLLIMMLKMIFN----QTSVEHCKTHTEKQKECNFFLIAVRLASLNQILDPWVYLLL 349
Query: 312 RRAVLRR 318
R+ +LR+
Sbjct: 350 RKILLRK 356
>gi|38505172 prostaglandin E receptor 3, subtype EP3 isoform 1 [Homo
sapiens]
Length = 425
Score = 177 bits (449), Expect = 1e-44
Identities = 109/307 (35%), Positives = 161/307 (52%), Gaps = 22/307 (7%)
Query: 30 FAASFCVVGLASNLLALSVLAGA-RQGGSHTRSSFLTFLCGLVLTDFLGLLVTGTIVVSQ 88
F + + G N LA+ +++ + R+ S + SFL + L LTD +G L+T +V+
Sbjct: 54 FPITMLLTGFVGNALAMLLVSRSYRRRESKRKKSFLLCIGWLALTDLVGQLLTTPVVIVV 113
Query: 89 HAALFEWHAVDPGCRLCRFMGVVMIFFGLSPLLLGAAMASERYLGITRPFSRPAVASQRR 148
+ + W +DP RLC F G+ M FGLS L + +AMA ER L I P + R
Sbjct: 114 YLSKQRWEHIDPSGRLCTFFGLTMTVFGLSSLFIASAMAVERALAIRAPHWYASHMKTRA 173
Query: 149 AWATVGLVWAAALALGLLPLLGVGRYTVQYPGSWCFLTLGAES---------GDVAFGLL 199
A + VW A LA LLP+LGVG+YTVQ+PG+WCF++ G G++ F
Sbjct: 174 TRAVLLGVWLAVLAFALLPVLGVGQYTVQWPGTWCFISTGRGGNGTSSSHNWGNLFFASA 233
Query: 200 FSMLGGLSVGLSFLLNTVSVATLCHVYHGQEAAQQRPRD---SEVEMMAQLLGIMVVASV 256
F+ LG L++ ++F N ++ L + A Q E QL+GIM V SV
Sbjct: 234 FAFLGLLALTVTFSCNLATIKALVSRCRAKATASQSSAQWGRITTETAIQLMGIMCVLSV 293
Query: 257 CWLPLLVFIAQTVLRNPPAMSPAGQLSRTTEKE-----LLIYLRVATWNQILDPWVYILF 311
CW PLL+ + + + + TEK+ LI +R+A+ NQILDPWVY+L
Sbjct: 294 CWSPLLIMMLKMIFN----QTSVEHCKTHTEKQKECNFFLIAVRLASLNQILDPWVYLLL 349
Query: 312 RRAVLRR 318
R+ +LR+
Sbjct: 350 RKILLRK 356
>gi|186659506 prostaglandin E receptor 3, subtype EP3 isoform 4
[Homo sapiens]
Length = 390
Score = 177 bits (449), Expect = 1e-44
Identities = 109/307 (35%), Positives = 161/307 (52%), Gaps = 22/307 (7%)
Query: 30 FAASFCVVGLASNLLALSVLAGA-RQGGSHTRSSFLTFLCGLVLTDFLGLLVTGTIVVSQ 88
F + + G N LA+ +++ + R+ S + SFL + L LTD +G L+T +V+
Sbjct: 54 FPITMLLTGFVGNALAMLLVSRSYRRRESKRKKSFLLCIGWLALTDLVGQLLTTPVVIVV 113
Query: 89 HAALFEWHAVDPGCRLCRFMGVVMIFFGLSPLLLGAAMASERYLGITRPFSRPAVASQRR 148
+ + W +DP RLC F G+ M FGLS L + +AMA ER L I P + R
Sbjct: 114 YLSKQRWEHIDPSGRLCTFFGLTMTVFGLSSLFIASAMAVERALAIRAPHWYASHMKTRA 173
Query: 149 AWATVGLVWAAALALGLLPLLGVGRYTVQYPGSWCFLTLGAES---------GDVAFGLL 199
A + VW A LA LLP+LGVG+YTVQ+PG+WCF++ G G++ F
Sbjct: 174 TRAVLLGVWLAVLAFALLPVLGVGQYTVQWPGTWCFISTGRGGNGTSSSHNWGNLFFASA 233
Query: 200 FSMLGGLSVGLSFLLNTVSVATLCHVYHGQEAAQQRPRD---SEVEMMAQLLGIMVVASV 256
F+ LG L++ ++F N ++ L + A Q E QL+GIM V SV
Sbjct: 234 FAFLGLLALTVTFSCNLATIKALVSRCRAKATASQSSAQWGRITTETAIQLMGIMCVLSV 293
Query: 257 CWLPLLVFIAQTVLRNPPAMSPAGQLSRTTEKE-----LLIYLRVATWNQILDPWVYILF 311
CW PLL+ + + + + TEK+ LI +R+A+ NQILDPWVY+L
Sbjct: 294 CWSPLLIMMLKMIFN----QTSVEHCKTHTEKQKECNFFLIAVRLASLNQILDPWVYLLL 349
Query: 312 RRAVLRR 318
R+ +LR+
Sbjct: 350 RKILLRK 356
>gi|88758606 prostaglandin F receptor isoform b precursor [Homo
sapiens]
Length = 297
Score = 147 bits (371), Expect = 1e-35
Identities = 93/245 (37%), Positives = 133/245 (54%), Gaps = 6/245 (2%)
Query: 21 ERRLIASPWFAASFCVVGLASNLLALSVLAGARQG-GSHTRSSFLTFLCGLVLTDFLGLL 79
E RL S +F+ F VG+ SN LA+++L A Q +++SFL GLV+TDF G L
Sbjct: 25 ENRL--SVFFSVIFMTVGILSNSLAIAILMKAYQRFRQKSKASFLLLASGLVITDFFGHL 82
Query: 80 VTGTIVVSQHAALFEWHAVDPGCRLCRFMGVVMIFFGLSPLLLGAAMASERYLGITRPFS 139
+ G I V +A+ EW D LC G+ M+F GL PLLLG+ MA ER +G+T+P
Sbjct: 83 INGAIAVFVYASDKEWIRFDQSNVLCSIFGICMVFSGLCPLLLGSVMAIERCIGVTKPIF 142
Query: 140 RPAVASQRRAWATVGLVWAAALALGLLPLLGVGRYTVQYPGSWCFLTLG--AESGDVAFG 197
+ + + V A+ + LLP+LG Y +Q +WCF + D +
Sbjct: 143 HSTKITSKHVKMMLSGVCLFAVFIALLPILGHRDYKIQASRTWCFYNTEDIKDWEDRFYL 202
Query: 198 LLFSMLGGLSVGLSFLLNTVSVATLCHVYHGQEAAQQRPRDSEVEMMAQLLGIMVVASVC 257
LLFS LG L++G+S L N ++ TL V + +Q R +EM+ QLL IM V+ +C
Sbjct: 203 LLFSFLGLLALGVSLLCNAITGITLLRVKFKSQQHRQ-GRSHHLEMVIQLLAIMCVSCIC 261
Query: 258 WLPLL 262
W P L
Sbjct: 262 WSPFL 266
>gi|4506263 prostaglandin I2 (prostacyclin) receptor (IP) [Homo
sapiens]
Length = 386
Score = 130 bits (327), Expect = 2e-30
Identities = 100/293 (34%), Positives = 144/293 (49%), Gaps = 21/293 (7%)
Query: 36 VVGLASNLLALSVLAGARQGGSHTRSSFLTFLCGLVLTDFLGLLVTGTIVVSQHAALFEW 95
V G+ N LAL +L+ R S+F + GL TD LG V +A
Sbjct: 25 VAGVVGNGLALGILSARRPARP---SAFAVLVTGLAATDLLGTSFLSPAVFVAYARNSSL 81
Query: 96 HAVDPGC-RLCRFMGVVMIFFGLSPLLLGAAMASERYLGITRPFSRPAVASQRRAWATVG 154
+ G LC M FFGL+ +L+ AMA ER L ++ P+ + R A +
Sbjct: 82 LGLARGGPALCDAFAFAMTFFGLASMLILFAMAVERCLALSHPYLYAQLDGPRCARLALP 141
Query: 155 LVWAAALALGLLPLLGVGRYTVQYPGSWCFLTL-GAESGDVAFGLLFSMLGGLSVGLSFL 213
++A + LPLLG+G++ PGSWCFL + A+ G AF L ++ L L V FL
Sbjct: 142 AIYAFCVLFCALPLLGLGQHQQYCPGSWCFLRMRWAQPGGAAFSLAYAGLVALLVAAIFL 201
Query: 214 LNTVSVATLCHVYHGQEAAQ----QRPR--DSEVEMMAQLLGIMVVASVCWLPLLVFIAQ 267
N +LC +Y Q+ Q RPR + EV+ + L + VV +VC LPL
Sbjct: 202 CNGSVTLSLCRMYRQQKRHQGSLGPRPRTGEDEVDHLILLALMTVVMAVCSLPL------ 255
Query: 268 TVLRNPPAMSPAGQLSRTTEKELLIYLRVATWNQILDPWVYILFRRAVLRRLQ 320
T+ A++P ++E L+ R +N ILDPWV+ILFR+AV +RL+
Sbjct: 256 TIRCFTQAVAP----DSSSEMGDLLAFRFYAFNPILDPWVFILFRKAVFQRLK 304
>gi|4506259 prostaglandin E receptor 4, subtype EP4 [Homo sapiens]
Length = 488
Score = 115 bits (288), Expect = 6e-26
Identities = 88/344 (25%), Positives = 155/344 (45%), Gaps = 52/344 (15%)
Query: 15 TNITLEERRLIASPWFAASFCVVGLASNLLALSVLAGARQGGSHTRSSFLTFLCGLVLTD 74
++ +L RL + A + G+ NL+A+ VL +R+ T +F T +CGL +TD
Sbjct: 8 SSASLSPDRLNSPVTIPAVMFIFGVVGNLVAIVVLCKSRKEQKET--TFYTLVCGLAVTD 65
Query: 75 FLGLLVTGTIVVSQHAALFEWHAVDPGCRLCRFMGVVMIFFGLSPLLLGAAMASERYLGI 134
LG L+ + ++ + +W P LC + +++FF LS L + AM+ ERYL I
Sbjct: 66 LLGTLLVSPVTIATYMK-GQWPGGQP---LCEYSTFILLFFSLSGLSIICAMSVERYLAI 121
Query: 135 TRPFSRPAVASQRRAWATVGLVWAAALALGLLPLLGVGRYTVQYPGSWCFLTLGAE-SGD 193
+ +R A T+ V+A+ + LP +G+G +QYP +WCF+ +
Sbjct: 122 NHAYFYSHYVDKRLAGLTLFAVYASNVLFCALPNMGLGSSRLQYPDTWCFIDWTTNVTAH 181
Query: 194 VAFGLLFSMLGGLSVGLSFLLNTVSVATLCHV--------------YHGQEAAQ------ 233
A+ +++ + + L N + L + +H AA
Sbjct: 182 AAYSYMYAGFSSFLILATVLCNVLVCGALLRMHRQFMRRTSLGTEQHHAAAAASVASRGH 241
Query: 234 -------------------QRPRDSEVEMMAQLLGIMVVASVCWLPLLVFIAQTVLRNPP 274
+R +E++M+ L+ +V +C +PL+V + L P
Sbjct: 242 PAASPALPRLSDFRRRRSFRRIAGAEIQMVILLIATSLVVLICSIPLVVRVFVNQLYQP- 300
Query: 275 AMSPAGQLSRTTEKELLIYLRVATWNQILDPWVYILFRRAVLRR 318
S ++S+ + L +R+A+ N ILDPW+YIL R+ VL +
Sbjct: 301 --SLEREVSKNPD---LQAIRIASVNPILDPWIYILLRKTVLSK 339
>gi|31881630 prostaglandin E receptor 2 (subtype EP2), 53kDa [Homo
sapiens]
Length = 358
Score = 114 bits (284), Expect = 2e-25
Identities = 98/331 (29%), Positives = 150/331 (45%), Gaps = 37/331 (11%)
Query: 27 SPWFAASFCVVGLASNLLALSVLA-------GARQGGSHTRSSFLTFLCGLVLTDFLGLL 79
SP ++ G+ NL+AL++LA G G + S F + LV TD LG
Sbjct: 24 SPAISSVMFSAGVLGNLIALALLARRWRGDVGCSAGRRSSLSLFHVLVTELVFTDLLGTC 83
Query: 80 VTGTIVVSQHAALFEWHAVDPGCRLCRFMGVVMIFFGLSPLLLGAAMASERYLGITRPFS 139
+ +V++ +A A+ P R C + M FF L+ +L+ AMA ERYL I P+
Sbjct: 84 LISPVVLASYARNQTLVALAPESRACTYFAFAMTFFSLATMLMLFAMALERYLSIGHPYF 143
Query: 140 RPAVASQRRAWATVGLVWAAALALGLLPLLGVGRYTVQYPGSWCFLTLGAESGDVAFG-- 197
S+ A + +++A +L LPLL G+Y PG+WCF+ G + +
Sbjct: 144 YQRRVSRSGGLAVLPVIYAVSLLFCSLPLLDYGQYVQYCPGTWCFIRHGRTAYLQLYATL 203
Query: 198 LLFSMLGGLSVGLSFLLNTV-----SVATLC--HVYHGQEAAQQRPRDSEVEMMAQ---- 246
LL ++ L+ S +LN + S + C + G+ R R V M +
Sbjct: 204 LLLLIVSVLACNFSVILNLIRMHRRSRRSRCGPSLGSGRGGPGARRRGERVSMAEETDHL 263
Query: 247 -LLGIMVVA-SVCWLPLLVFIAQTVLRNPPAMSPAGQLSRTTEKELLIYLRVATWNQILD 304
LL IM + +VC LP +F + + S EK L LR + N I+D
Sbjct: 264 ILLAIMTITFAVCSLPFTIF------------AYMNETSSRKEKWDLQALRFLSINSIID 311
Query: 305 PWVYILFRRAVLRRLQPRLSTRPRSLSLQPQ 335
PWV+ + R VLR ++ L R +SL+ Q
Sbjct: 312 PWVFAILRPPVLRLMRSVLCCR---ISLRTQ 339
>gi|28466969 prostaglandin D2 receptor [Homo sapiens]
Length = 359
Score = 104 bits (260), Expect = 1e-22
Identities = 91/322 (28%), Positives = 144/322 (44%), Gaps = 41/322 (12%)
Query: 38 GLASNLLALSVLAGARQGGSHTR------SSFLTFLCGLVLTDFLGLLVTGTIVVSQHAA 91
GL NLLAL +LA + G R S F +CGL +TD LG + +V++ +A
Sbjct: 30 GLLGNLLALGLLARSGLGWCSRRPLRPLPSVFYMLVCGLTVTDLLGKCLLSPVVLAAYAQ 89
Query: 92 LFEWHAVDPGC--RLCRFMGVVMIFFGLSPLLLGAAMASERYLGITRPFSRPAVASQRRA 149
+ P LC+ M FFGLS L AMA E +L + PF + R
Sbjct: 90 NRSLRVLAPALDNSLCQAFAFFMSFFGLSSTLQLLAMALECWLSLGHPFFYRRHITLRLG 149
Query: 150 WATVGLVWAAALALGLLPLLGVGRYTVQYPGSWCFLTLGAESGDVA---FGLLFSMLGGL 206
+V A +LA LP +G G++ PG+WCF+ + E G ++ + +L+S L L
Sbjct: 150 ALVAPVVSAFSLAFCALPFMGFGKFVQYCPGTWCFIQMVHEEGSLSVLGYSVLYSSLMAL 209
Query: 207 SVGLSFLLNTVSVATLCHVYHGQEAAQQRPRD--------------------SEVEMMAQ 246
V + L N + + ++Y Q+ PR E++ +
Sbjct: 210 LVLATVLCN---LGAMRNLYAMHRRLQRHPRSCTRDCAEPRADGREASPQPLEELDHLLL 266
Query: 247 LLGIMVVASVCWLPLLVFIAQTVLRNPPAMSPAGQLSRTTEK-ELLIYLRVATWNQILDP 305
L + V+ ++C LP++ A + +RT+E+ E L LR + I+DP
Sbjct: 267 LALMTVLFTMCSLPVIYRAYY------GAFKDVKEKNRTSEEAEDLRALRFLSVISIVDP 320
Query: 306 WVYILFRRAVLRRLQPRLSTRP 327
W++I+FR V R ++ RP
Sbjct: 321 WIFIIFRSPVFRIFFHKIFIRP 342
>gi|9506745 urotensin 2 receptor [Homo sapiens]
Length = 389
Score = 60.5 bits (145), Expect = 2e-09
Identities = 80/298 (26%), Positives = 119/298 (39%), Gaps = 40/298 (13%)
Query: 36 VVGLASNLLALSVLAGARQGGSHTRSSFLTFLCGLVLTDFLGLLVTGTIVVSQHAALFEW 95
VVG+ N L V + + + S ++ L L D L LL IV + EW
Sbjct: 63 VVGVVGNAYTLVVTCRSLRAVA----SMYVYVVNLALADLLYLLSIPFIVATYVTK--EW 116
Query: 96 HAVDPGCRLCRFMGVVMIFFGLSPLLLGAA------MASERYLGITRPFSRPAVASQRRA 149
H D GCR + FGL L + A+ M+SERY + RP R
Sbjct: 117 HFGDVGCR---------VLFGLDFLTMHASIFTLTVMSSERYAAVLRPLDTVQRPKGYRK 167
Query: 150 WATVGLVWAAALALGLLPLLGVGRYTVQYPGSWCFLTLGAESGDVAFGLLF--SMLG-GL 206
+G W AL L LP++ R + P S C G + LLF S+ G GL
Sbjct: 168 LLALG-TWLLALLL-TLPVMLAMRLVRRGPKSLCLPAWGPRAHRAYLTLLFATSIAGPGL 225
Query: 207 SVGLSFLLNTVSVATLCHVY-HGQEAAQQRPRDSEVEMMAQLLGIMVVASVCWLPLLVFI 265
+GL + A L Y Q A+ +R R + +LGI+++ C+LP ++
Sbjct: 226 LIGLLY-------ARLARAYRRSQRASFKRARRPGARALRLVLGIVLLFWACFLPFWLWQ 278
Query: 266 AQTVLRNPPAMSPAGQLSRTTEKELLIYLRVATWNQILDPWVYILFRRAVLRRLQPRL 323
P ++P RT + + N +P++Y L R L+ R+
Sbjct: 279 LLAQYHQAP-LAP-----RTARIVNYLTTCLTYGNSCANPFLYTLLTRNYRDHLRGRV 330
>gi|15150803 opsin 4 isoform 1 [Homo sapiens]
Length = 478
Score = 58.5 bits (140), Expect = 8e-09
Identities = 44/139 (31%), Positives = 65/139 (46%), Gaps = 8/139 (5%)
Query: 36 VVGLASNLLALSVLAGARQGGSHTRSSFLTFLCGLVLTDFLGLLVTGTIVVSQHAALFEW 95
+ G+ NL + +R R+ F+ L ++DFL + T V + +W
Sbjct: 82 LTGMLGNLTVIYTFCRSRS----LRTPANMFIINLAVSDFL-MSFTQAPVFFTSSLYKQW 136
Query: 96 HAVDPGCRLCRFMGVVMIFFGLSPLLLGAAMASERYLGITRPFSRPAVASQRRAWATVGL 155
+ GC F G + FG+S ++ A+A +RYL ITRP + VAS+RRA +
Sbjct: 137 LFGETGCEFYAFCGAL---FGISSMITLTAIALDRYLVITRPLATFGVASKRRAAFVLLG 193
Query: 156 VWAAALALGLLPLLGVGRY 174
VW ALA L P G Y
Sbjct: 194 VWLYALAWSLPPFFGWSAY 212
>gi|71999143 opsin 4 isoform 2 [Homo sapiens]
Length = 489
Score = 57.0 bits (136), Expect = 2e-08
Identities = 39/109 (35%), Positives = 55/109 (50%), Gaps = 4/109 (3%)
Query: 66 FLCGLVLTDFLGLLVTGTIVVSQHAALFEWHAVDPGCRLCRFMGVVMIFFGLSPLLLGAA 125
F+ L ++DFL + T V + +W + GC F G + FG+S ++ A
Sbjct: 119 FIINLAVSDFL-MSFTQAPVFFTSSLYKQWLFGETGCEFYAFCGAL---FGISSMITLTA 174
Query: 126 MASERYLGITRPFSRPAVASQRRAWATVGLVWAAALALGLLPLLGVGRY 174
+A +RYL ITRP + VAS+RRA + VW ALA L P G Y
Sbjct: 175 IALDRYLVITRPLATFGVASKRRAAFVLLGVWLYALAWSLPPFFGWSAY 223
>gi|4885325 G protein-coupled receptor 3 [Homo sapiens]
Length = 330
Score = 55.1 bits (131), Expect = 9e-08
Identities = 80/324 (24%), Positives = 128/324 (39%), Gaps = 65/324 (20%)
Query: 4 NGSSLGPCFRPTNITLEERRLIASP--WFAASFCVVGL---ASNLLALSVLAGARQGGSH 58
N SS+GP PT + SP W C+ G N L ++++ G
Sbjct: 20 NVSSVGPAEGPTGPAAP----LPSPKAWDVV-LCISGTLVSCENALVVAIIVGTPA---- 70
Query: 59 TRSSFLTFLCGLVLTDFLGLLVTGTIVVSQHAALFEWHAVDPGCRLCRFMGVVMIFFGLS 118
R+ + L + D L+ G +V AA+F + + L +GV+ + F S
Sbjct: 71 FRAPMFLLVGSLAVAD----LLAGLGLVLHFAAVFCIGSAEMSLVL---VGVLAMAFTAS 123
Query: 119 PLLLGAAMASERYLGITRPFSRPAVASQRRAWATVGLVWAAALALGLLPLL------GVG 172
L A+ +RYL + + + + R + + LVW AL LGLLP+L G+
Sbjct: 124 IGSL-LAITVDRYLSLYNALTYYSETTVTRTYVMLALVWGGALGLGLLPVLAWNCLDGLT 182
Query: 173 RYTVQYPGSWCFLTLGAESGDVAFGLLFSMLGGLSVGLSFLLNTVSVATLCHVY--HGQE 230
V YP S L + A + + FG++ + A +C + H Q+
Sbjct: 183 TCGVVYPLSKNHLVVLAIAFFMVFGIMLQL----------------YAQICRIVCRHAQQ 226
Query: 231 AAQQRPRDSEVEMMAQLLGIMVVASV------CWLPLLVFIAQTVLRNPPAMSPAGQLSR 284
A QR +A GI +A V CWLP V+ +PP +
Sbjct: 227 IALQRHLLPASHYVATRKGIATLAVVLGAFAACWLPFTVYCLLGDAHSPPLYT------- 279
Query: 285 TTEKELLIYLRVATWNQILDPWVY 308
+ L AT+N +++P +Y
Sbjct: 280 ------YLTLLPATYNSMINPIIY 297
>gi|4557859 somatostatin receptor 2 [Homo sapiens]
Length = 369
Score = 54.3 bits (129), Expect = 2e-07
Identities = 63/283 (22%), Positives = 115/283 (40%), Gaps = 33/283 (11%)
Query: 35 CVVGLASNLLALSVLAGARQGGSHTRSSFLTFLCGLVLTDFLGLLVTGTIVVSQHAALFE 94
C++GL N L + V+ + + T ++ L + D L +L G ++ AL
Sbjct: 54 CIIGLCGNTLVIYVILRYAKMKTITN----IYILNLAIADELFML--GLPFLAMQVALVH 107
Query: 95 WHAVDPGCRLCRFMGVVMIFFGLSPLLLGAAMASERYLGITRPFSRPAVASQRRAWATVG 154
W G +CR + V + + M+ +RYL + P R A
Sbjct: 108 WPF---GKAICRVVMTVDGINQFTSIFCLTVMSIDRYLAVVHPIKSAKWRRPRTAKMITM 164
Query: 155 LVWAAALALGLLPLLGVGRYTVQYPGSWCFLTLGAESGDVAFG-LLFSMLGGLSVGLSFL 213
VW +L + L ++ G + Q+ S C + ESG G ++++ + G V L
Sbjct: 165 AVWGVSLLVILPIMIYAGLRSNQWGRSSCTINWPGESGAWYTGFIIYTFILGFLVPL--- 221
Query: 214 LNTVSVATLCHVY-------HGQEAAQQRPRDSEVEMMAQLLGIMVVASVCWLPLLVFIA 266
++ LC+++ G + + SE ++ + ++ V CWLP +F
Sbjct: 222 ----TIICLCYLFIIIKVKSSGIRVGSSKRKKSEKKVTRMVSIVVAVFIFCWLPFYIFNV 277
Query: 267 QTVLRNPPAMSPAGQLSRTTEKELLIYLRVATW-NQILDPWVY 308
+V A+SP L K + ++ V T+ N +P +Y
Sbjct: 278 SSV---SMAISPTPAL-----KGMFDFVVVLTYANSCANPILY 312
>gi|148228791 G protein-coupled receptor 30 [Homo sapiens]
Length = 375
Score = 53.5 bits (127), Expect = 3e-07
Identities = 50/207 (24%), Positives = 87/207 (42%), Gaps = 13/207 (6%)
Query: 104 LCRFMGVVMIFFGLSPLLLGAAMASERYLGITRPFSRPAVASQRRAWATVGLVWAAALAL 163
LC FM + + S + M+ +RY+ + R ++ A + GL+W A+++
Sbjct: 129 LCTFMSLFLQVNMYSSVFFLTWMSFDRYIALARAMRCSLFRTKHHARLSCGLIWMASVSA 188
Query: 164 GLLPLLGVGRYTVQYPGSWCFLTLGAESGDVAFGLLFSMLGGLSVGLSFLLNTVSVATLC 223
L+P V +Q+ CF L ++ +GL + L V V
Sbjct: 189 TLVPFTAV---HLQHTDEACFCFADVREVQWLEVTLGFIVPFAIIGLCYSL-IVRVLVRA 244
Query: 224 HVYHGQEAAQQRPRDSEVEMMAQLLGIMVVASVCWLPLLVFIAQTVL-RNPPAMSPAGQL 282
H + G +Q+ + +L +++V VCWLP VFI+ +L R P +P Q
Sbjct: 245 HRHRGLRPRRQK-------ALRMILAVVLVFFVCWLPENVFISVHLLQRTQPGAAPCKQS 297
Query: 283 SRTTEKELLIYLRVATW-NQILDPWVY 308
R + +A + N L+P +Y
Sbjct: 298 FRHAHPLTGHIVNLAAFSNSCLNPLIY 324
>gi|91106714 G protein-coupled receptor 30 [Homo sapiens]
Length = 375
Score = 53.5 bits (127), Expect = 3e-07
Identities = 50/207 (24%), Positives = 87/207 (42%), Gaps = 13/207 (6%)
Query: 104 LCRFMGVVMIFFGLSPLLLGAAMASERYLGITRPFSRPAVASQRRAWATVGLVWAAALAL 163
LC FM + + S + M+ +RY+ + R ++ A + GL+W A+++
Sbjct: 129 LCTFMSLFLQVNMYSSVFFLTWMSFDRYIALARAMRCSLFRTKHHARLSCGLIWMASVSA 188
Query: 164 GLLPLLGVGRYTVQYPGSWCFLTLGAESGDVAFGLLFSMLGGLSVGLSFLLNTVSVATLC 223
L+P V +Q+ CF L ++ +GL + L V V
Sbjct: 189 TLVPFTAV---HLQHTDEACFCFADVREVQWLEVTLGFIVPFAIIGLCYSL-IVRVLVRA 244
Query: 224 HVYHGQEAAQQRPRDSEVEMMAQLLGIMVVASVCWLPLLVFIAQTVL-RNPPAMSPAGQL 282
H + G +Q+ + +L +++V VCWLP VFI+ +L R P +P Q
Sbjct: 245 HRHRGLRPRRQK-------ALRMILAVVLVFFVCWLPENVFISVHLLQRTQPGAAPCKQS 297
Query: 283 SRTTEKELLIYLRVATW-NQILDPWVY 308
R + +A + N L+P +Y
Sbjct: 298 FRHAHPLTGHIVNLAAFSNSCLNPLIY 324
>gi|4504091 G protein-coupled receptor 30 [Homo sapiens]
Length = 375
Score = 53.5 bits (127), Expect = 3e-07
Identities = 50/207 (24%), Positives = 87/207 (42%), Gaps = 13/207 (6%)
Query: 104 LCRFMGVVMIFFGLSPLLLGAAMASERYLGITRPFSRPAVASQRRAWATVGLVWAAALAL 163
LC FM + + S + M+ +RY+ + R ++ A + GL+W A+++
Sbjct: 129 LCTFMSLFLQVNMYSSVFFLTWMSFDRYIALARAMRCSLFRTKHHARLSCGLIWMASVSA 188
Query: 164 GLLPLLGVGRYTVQYPGSWCFLTLGAESGDVAFGLLFSMLGGLSVGLSFLLNTVSVATLC 223
L+P V +Q+ CF L ++ +GL + L V V
Sbjct: 189 TLVPFTAV---HLQHTDEACFCFADVREVQWLEVTLGFIVPFAIIGLCYSL-IVRVLVRA 244
Query: 224 HVYHGQEAAQQRPRDSEVEMMAQLLGIMVVASVCWLPLLVFIAQTVL-RNPPAMSPAGQL 282
H + G +Q+ + +L +++V VCWLP VFI+ +L R P +P Q
Sbjct: 245 HRHRGLRPRRQK-------ALRMILAVVLVFFVCWLPENVFISVHLLQRTQPGAAPCKQS 297
Query: 283 SRTTEKELLIYLRVATW-NQILDPWVY 308
R + +A + N L+P +Y
Sbjct: 298 FRHAHPLTGHIVNLAAFSNSCLNPLIY 324
>gi|4501957 alpha-1D-adrenergic receptor [Homo sapiens]
Length = 572
Score = 52.8 bits (125), Expect = 5e-07
Identities = 56/226 (24%), Positives = 97/226 (42%), Gaps = 29/226 (12%)
Query: 30 FAASFCVVGLASNLLALSVLAGARQGGSHTRSSFLTFLCGLVLTDFLGLLVTGTIV-VSQ 88
F A+F ++ +A NLL + +A R H ++ F+ L + D LL++ T++ S
Sbjct: 102 FLAAFILMAVAGNLLVILSVACNR----HLQTVTNYFIVNLAVAD---LLLSATVLPFSA 154
Query: 89 HAALFEWHAVDPGCRLCRFMGVVMIFFGLSPLLLGAAMASERYLGITRPFSRPAVASQRR 148
+ + A G C V + + +L ++ +RY+G+ PA+ ++R+
Sbjct: 155 TMEVLGFWAF--GRAFCDVWAAVDVLCCTASILSLCTISVDRYVGVRHSLKYPAIMTERK 212
Query: 149 AWATVGLVWAAALALGLLPLLGVGRYTVQYPGSWCFLTLGAESGDVAFGLLFSMLGGLSV 208
A A + L+W AL + + PLLG + P F + E+G F SV
Sbjct: 213 AAAILALLWVVALVVSVGPLLG---WKEPVPPDERFCGITEEAGYAVFS---------SV 260
Query: 209 GLSFLLNTVSVATLCHVY-------HGQEAAQQRPRDSEVEMMAQL 247
+L V V C VY EA +R R E++ ++
Sbjct: 261 CSFYLPMAVIVVMYCRVYVVARSTTRSLEAGVKRERGKASEVVLRI 306
>gi|64085121 thyroid stimulating hormone receptor isoform 1
precursor [Homo sapiens]
Length = 764
Score = 52.0 bits (123), Expect = 8e-07
Identities = 70/318 (22%), Positives = 122/318 (38%), Gaps = 47/318 (14%)
Query: 12 FRPTNITLEERRLIASPWFAASFCVVGLASNLLALSVLAGARQGGSHTRSSFLTFL-CGL 70
F P + + L WF + ++G N+ L +L SH + + FL C L
Sbjct: 405 FNPCEDIMGYKFLRIVVWFVSLLALLG---NVFVLLILLT-----SHYKLNVPRFLMCNL 456
Query: 71 VLTDF---LGLLVTGTIVVSQHAALFEWHAVD----PGCRLCRFMGVVMIFFGLSPLLLG 123
DF + LL+ ++ + H+ + HA+D PGC F V + L +
Sbjct: 457 AFADFCMGMYLLLIASVDLYTHSEYYN-HAIDWQTGPGCNTAGFFTVFASELSVYTLTV- 514
Query: 124 AAMASERYLGITRPFSRPAVASQRRAWATVGLVWAAALALGLLPLLGVGRYTVQYPGSWC 183
+ ER+ IT R A A + W L LLPL+G+ Y S C
Sbjct: 515 --ITLERWYAITFAMRLDRKIRLRHACAIMVGGWVCCFLLALLPLVGISSYA---KVSIC 569
Query: 184 FLTLGAESGDVAFGLLFSMLGGLSVGLSFLLNTVSVATLC----HVYHGQEAAQQRPRDS 239
L + E+ ++F + LN V+ +C +Y Q P D
Sbjct: 570 -LPMDTETPLALAYIVFVL----------TLNIVAFVIVCCCYVKIYITVRNPQYNPGDK 618
Query: 240 EVEMMAQLLGIMVVASVCWLPLLVFIAQTVLRNPPAMSPAGQLSRTTEKELLIYLRVATW 299
+ ++ ++ ++ +C P+ + +L P L + ++L+ L
Sbjct: 619 DTKIAKRMAVLIFTDFICMAPISFYALSAILNKP--------LITVSNSKILLVL-FYPL 669
Query: 300 NQILDPWVYILFRRAVLR 317
N +P++Y +F +A R
Sbjct: 670 NSCANPFLYAIFTKAFQR 687
>gi|23463303 purinergic receptor P2Y11 [Homo sapiens]
Length = 374
Score = 52.0 bits (123), Expect = 8e-07
Identities = 57/197 (28%), Positives = 82/197 (41%), Gaps = 18/197 (9%)
Query: 36 VVGLASNLLALSVLAGARQGGSHTRSSFLTFLCGLVLTDFLGLLVTGTIVVSQHAALFEW 95
+V +ASN LAL + +Q H + F L ++D L L + + W
Sbjct: 40 LVAVASNGLALYRFSIRKQRPWHPA---VVFSVQLAVSDLLCALTLPPLAAYLYPPK-HW 95
Query: 96 HAVDPGCRLCRFMGVVMIFFGLSPLLLGAAMASERYLGITRPFSRPAVASQRRAWA--TV 153
+ CRL RF+ + L ++ ++ RYLGI PF + + AWA
Sbjct: 96 RYGEAACRLERFLFTCNL---LGSVIFITCISLNRYLGIVHPFFARSHLRPKHAWAVSAA 152
Query: 154 GLVWAAALALGLL-------PLLGVGRYTVQYPGSWCFLTLG-AESGDVAFGLLFSMLGG 205
G V AA LA+ L P G G +V P + C LG A+ G A+ +L G
Sbjct: 153 GWVLAALLAMPTLSFSHLKRPQQGAGNCSVARPEA-CIKCLGTADHGLAAYRAYSLVLAG 211
Query: 206 LSVGLSFLLNTVSVATL 222
L GL LL + L
Sbjct: 212 LGCGLPLLLTLAAYGAL 228
>gi|99028871 PPAN-P2RY11 protein [Homo sapiens]
Length = 794
Score = 52.0 bits (123), Expect = 8e-07
Identities = 57/197 (28%), Positives = 82/197 (41%), Gaps = 18/197 (9%)
Query: 36 VVGLASNLLALSVLAGARQGGSHTRSSFLTFLCGLVLTDFLGLLVTGTIVVSQHAALFEW 95
+V +ASN LAL + +Q H + F L ++D L L + + W
Sbjct: 460 LVAVASNGLALYRFSIRKQRPWHPA---VVFSVQLAVSDLLCALTLPPLAAYLYPPK-HW 515
Query: 96 HAVDPGCRLCRFMGVVMIFFGLSPLLLGAAMASERYLGITRPFSRPAVASQRRAWA--TV 153
+ CRL RF+ + L ++ ++ RYLGI PF + + AWA
Sbjct: 516 RYGEAACRLERFLFTCNL---LGSVIFITCISLNRYLGIVHPFFARSHLRPKHAWAVSAA 572
Query: 154 GLVWAAALALGLL-------PLLGVGRYTVQYPGSWCFLTLG-AESGDVAFGLLFSMLGG 205
G V AA LA+ L P G G +V P + C LG A+ G A+ +L G
Sbjct: 573 GWVLAALLAMPTLSFSHLKRPQQGAGNCSVARPEA-CIKCLGTADHGLAAYRAYSLVLAG 631
Query: 206 LSVGLSFLLNTVSVATL 222
L GL LL + L
Sbjct: 632 LGCGLPLLLTLAAYGAL 648
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.327 0.139 0.437
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,280,923
Number of Sequences: 37866
Number of extensions: 493748
Number of successful extensions: 2073
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 136
Number of HSP's successfully gapped in prelim test: 173
Number of HSP's that attempted gapping in prelim test: 1816
Number of HSP's gapped (non-prelim): 343
length of query: 343
length of database: 18,247,518
effective HSP length: 103
effective length of query: 240
effective length of database: 14,347,320
effective search space: 3443356800
effective search space used: 3443356800
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.