Guide to the Human Genome
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Search of human proteins with 4507369

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4507369 tyrosine aminotransferase [Homo sapiens]
         (454 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4507369 tyrosine aminotransferase [Homo sapiens]                   931   0.0  
gi|169881279 kynurenine aminotransferase I isoform a [Homo sapiens]    84   2e-16
gi|95147551 kynurenine aminotransferase I isoform a [Homo sapiens]     84   2e-16
gi|215599424 glutamic pyruvate transaminase 2 isoform 2 [Homo sa...    82   1e-15
gi|19263340 glutamic pyruvate transaminase 2 isoform 1 [Homo sap...    82   1e-15
gi|56713254 kynurenine aminotransferase III isoform 1 [Homo sapi...    79   8e-15
gi|56713256 kynurenine aminotransferase III isoform 2 [Homo sapi...    79   8e-15
gi|169881281 kynurenine aminotransferase I isoform b [Homo sapiens]    74   4e-13
gi|4885351 glutamic pyruvate transaminase [Homo sapiens]               71   2e-12
gi|149944424 1-aminocyclopropane-1-carboxylate synthase homolog ...    62   1e-09
gi|187936925 1-aminocyclopropane-1-carboxylate synthase homolog ...    59   7e-09
gi|14211921 1-aminocyclopropane-1-carboxylate synthase homolog [...    59   7e-09
gi|7705897 kynurenine aminotransferase II [Homo sapiens]               45   2e-04
gi|33469970 kynurenine aminotransferase II [Homo sapiens]              45   2e-04
gi|153792230 hypothetical protein LOC57670 [Homo sapiens]              32   1.2  
gi|148596944 C2 calcium-dependent domain containing 3 [Homo sapi...    32   1.2  
gi|23503267 ectonucleotide pyrophosphatase/phosphodiesterase 6 [...    32   1.2  
gi|37595528 polyhomeotic-like 2 isoform a [Homo sapiens]               32   1.6  
gi|28559088 laminin alpha 2 subunit isoform a precursor [Homo sa...    31   2.0  
gi|150456451 hypothetical protein LOC54914 [Homo sapiens]              30   3.5  
gi|32307132 NFS1 nitrogen fixation 1 [Homo sapiens]                    30   3.5  
gi|60498973 myelin transcription factor 1-like [Homo sapiens]          30   4.5  
gi|9789865 eukaryotic translation initiation factor 4E nuclear i...    29   7.7  
gi|40254949 erythrocyte membrane protein band 4.1 like 5 [Homo s...    29   7.7  

>gi|4507369 tyrosine aminotransferase [Homo sapiens]
          Length = 454

 Score =  931 bits (2405), Expect = 0.0
 Identities = 454/454 (100%), Positives = 454/454 (100%)

Query: 1   MDPYMIQMSSKGNLPSILDVHVNVGGRSSVPGKMKGRKARWSVRPSDMAKKTFNPIRAIV 60
           MDPYMIQMSSKGNLPSILDVHVNVGGRSSVPGKMKGRKARWSVRPSDMAKKTFNPIRAIV
Sbjct: 1   MDPYMIQMSSKGNLPSILDVHVNVGGRSSVPGKMKGRKARWSVRPSDMAKKTFNPIRAIV 60

Query: 61  DNMKVKPNPNKTMISLSIGDPTVFGNLPTDPEVTQAMKDALDSGKYNGYAPSIGFLSSRE 120
           DNMKVKPNPNKTMISLSIGDPTVFGNLPTDPEVTQAMKDALDSGKYNGYAPSIGFLSSRE
Sbjct: 61  DNMKVKPNPNKTMISLSIGDPTVFGNLPTDPEVTQAMKDALDSGKYNGYAPSIGFLSSRE 120

Query: 121 EIASYYHCPEAPLEAKDVILTSGCSQAIDLCLAVLANPGQNILVPRPGFSLYKTLAESMG 180
           EIASYYHCPEAPLEAKDVILTSGCSQAIDLCLAVLANPGQNILVPRPGFSLYKTLAESMG
Sbjct: 121 EIASYYHCPEAPLEAKDVILTSGCSQAIDLCLAVLANPGQNILVPRPGFSLYKTLAESMG 180

Query: 181 IEVKLYNLLPEKSWEIDLKQLEYLIDEKTACLIVNNPSNPCGSVFSKRHLQKILAVAARQ 240
           IEVKLYNLLPEKSWEIDLKQLEYLIDEKTACLIVNNPSNPCGSVFSKRHLQKILAVAARQ
Sbjct: 181 IEVKLYNLLPEKSWEIDLKQLEYLIDEKTACLIVNNPSNPCGSVFSKRHLQKILAVAARQ 240

Query: 241 CVPILADEIYGDMVFSDCKYEPLATLSTDVPILSCGGLAKRWLVPGWRLGWILIHDRRDI 300
           CVPILADEIYGDMVFSDCKYEPLATLSTDVPILSCGGLAKRWLVPGWRLGWILIHDRRDI
Sbjct: 241 CVPILADEIYGDMVFSDCKYEPLATLSTDVPILSCGGLAKRWLVPGWRLGWILIHDRRDI 300

Query: 301 FGNEIRDGLVKLSQRILGPCTIVQGALKSILCRTPGEFYHNTLSFLKSNADLCYGALAAI 360
           FGNEIRDGLVKLSQRILGPCTIVQGALKSILCRTPGEFYHNTLSFLKSNADLCYGALAAI
Sbjct: 301 FGNEIRDGLVKLSQRILGPCTIVQGALKSILCRTPGEFYHNTLSFLKSNADLCYGALAAI 360

Query: 361 PGLRPVRPSGAMYLMVGIEMEHFPEFENDVEFTERLVAEQSVHCLPATCFEYPNFIRVVI 420
           PGLRPVRPSGAMYLMVGIEMEHFPEFENDVEFTERLVAEQSVHCLPATCFEYPNFIRVVI
Sbjct: 361 PGLRPVRPSGAMYLMVGIEMEHFPEFENDVEFTERLVAEQSVHCLPATCFEYPNFIRVVI 420

Query: 421 TVPEVMMLEACSRIQEFCEQHYHCAEGSQEECDK 454
           TVPEVMMLEACSRIQEFCEQHYHCAEGSQEECDK
Sbjct: 421 TVPEVMMLEACSRIQEFCEQHYHCAEGSQEECDK 454


>gi|169881279 kynurenine aminotransferase I isoform a [Homo sapiens]
          Length = 422

 Score = 84.3 bits (207), Expect = 2e-16
 Identities = 79/357 (22%), Positives = 155/357 (43%), Gaps = 39/357 (10%)

Query: 84  FGNLPTDPEVTQAMKDALDSGKY--NGYAPSIGFLSSREEIASYYH--CPEAPLEAKDVI 139
           F + P      +A + A+ SG +  N Y  + G+    + +AS++     +     ++V+
Sbjct: 37  FPDFPPPDFAVEAFQHAV-SGDFMLNQYTKTFGYPPLTKILASFFGELLGQEIDPLRNVL 95

Query: 140 LTSGCSQAIDLCLAVLANPGQNILVPRPGFSLYKTLAESMGIEVKLYNLLP--------- 190
           +T G   A+      L + G  +++  P F  Y+ +    G      +L P         
Sbjct: 96  VTVGGYGALFTAFQALVDEGDEVIIIEPFFDCYEPMTMMAGGRPVFVSLKPGPIQNGELG 155

Query: 191 -EKSWEIDLKQLEYLIDEKTACLIVNNPSNPCGSVFSKRHLQKILAVAARQCVPILADEI 249
              +W++D  +L      +T  L++N P+NP G VFS+  L+ + ++  +  V  + DE+
Sbjct: 156 SSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVFSREELELVASLCQQHDVVCITDEV 215

Query: 250 YGDMVFSDCKYEPLATL-STDVPILSCGGLAKRWLVPGWRLGWILIHDRRDIFGNEIRDG 308
           Y  MV+   ++  +A+L       L+ G   K +   GW++GW+L  D        I   
Sbjct: 216 YQWMVYDGHQHISIASLPGMWERTLTIGSAGKTFSATGWKVGWVLGPD-------HIMKH 268

Query: 309 LVKLSQRILGPC-TIVQGAL------KSILCRTPGEFYHNTLSFLKSNADLCYGALAAIP 361
           L  + Q  +  C T  Q A+      + +L R P  ++      ++   D    +L ++ 
Sbjct: 269 LRTVHQNSVFHCPTQSQAAVAESFEREQLLFRQPSSYFVQFPQAMQRCRDHMIRSLQSV- 327

Query: 362 GLRPVRPSGAMYLMVGI-----EMEHFP---EFENDVEFTERLVAEQSVHCLPATCF 410
           GL+P+ P G+ +L+  I     +M   P   +   D  F + ++  + +  +P + F
Sbjct: 328 GLKPIIPQGSYFLITDISDFKRKMPDLPGAVDEPYDRRFVKWMIKNKGLVAIPVSIF 384


>gi|95147551 kynurenine aminotransferase I isoform a [Homo sapiens]
          Length = 422

 Score = 84.3 bits (207), Expect = 2e-16
 Identities = 79/357 (22%), Positives = 155/357 (43%), Gaps = 39/357 (10%)

Query: 84  FGNLPTDPEVTQAMKDALDSGKY--NGYAPSIGFLSSREEIASYYH--CPEAPLEAKDVI 139
           F + P      +A + A+ SG +  N Y  + G+    + +AS++     +     ++V+
Sbjct: 37  FPDFPPPDFAVEAFQHAV-SGDFMLNQYTKTFGYPPLTKILASFFGELLGQEIDPLRNVL 95

Query: 140 LTSGCSQAIDLCLAVLANPGQNILVPRPGFSLYKTLAESMGIEVKLYNLLP--------- 190
           +T G   A+      L + G  +++  P F  Y+ +    G      +L P         
Sbjct: 96  VTVGGYGALFTAFQALVDEGDEVIIIEPFFDCYEPMTMMAGGRPVFVSLKPGPIQNGELG 155

Query: 191 -EKSWEIDLKQLEYLIDEKTACLIVNNPSNPCGSVFSKRHLQKILAVAARQCVPILADEI 249
              +W++D  +L      +T  L++N P+NP G VFS+  L+ + ++  +  V  + DE+
Sbjct: 156 SSSNWQLDPMELAGKFTSRTKALVLNTPNNPLGKVFSREELELVASLCQQHDVVCITDEV 215

Query: 250 YGDMVFSDCKYEPLATL-STDVPILSCGGLAKRWLVPGWRLGWILIHDRRDIFGNEIRDG 308
           Y  MV+   ++  +A+L       L+ G   K +   GW++GW+L  D        I   
Sbjct: 216 YQWMVYDGHQHISIASLPGMWERTLTIGSAGKTFSATGWKVGWVLGPD-------HIMKH 268

Query: 309 LVKLSQRILGPC-TIVQGAL------KSILCRTPGEFYHNTLSFLKSNADLCYGALAAIP 361
           L  + Q  +  C T  Q A+      + +L R P  ++      ++   D    +L ++ 
Sbjct: 269 LRTVHQNSVFHCPTQSQAAVAESFEREQLLFRQPSSYFVQFPQAMQRCRDHMIRSLQSV- 327

Query: 362 GLRPVRPSGAMYLMVGI-----EMEHFP---EFENDVEFTERLVAEQSVHCLPATCF 410
           GL+P+ P G+ +L+  I     +M   P   +   D  F + ++  + +  +P + F
Sbjct: 328 GLKPIIPQGSYFLITDISDFKRKMPDLPGAVDEPYDRRFVKWMIKNKGLVAIPVSIF 384


>gi|215599424 glutamic pyruvate transaminase 2 isoform 2 [Homo
           sapiens]
          Length = 423

 Score = 82.0 bits (201), Expect = 1e-15
 Identities = 90/381 (23%), Positives = 157/381 (41%), Gaps = 50/381 (13%)

Query: 100 ALDSGKYNGYAPSIGFLSSREEIASYYHCPEA--PLEAKDVILTSGCSQAIDLCLAVLAN 157
           A        Y+ S G    RE++A+Y    +   P +  ++ LT+G S  I   L +L +
Sbjct: 41  ACGGNSLGSYSASQGVNCIREDVAAYITRRDGGVPADPDNIYLTTGASDGISTILKILVS 100

Query: 158 PG----QNILVPRPGFSLYKTLAESMGIEVKLYNLLPEKSWEIDLKQLEYLIDE------ 207
            G      +++P P + LY  +   +      Y L  E  W +++ +L   + E      
Sbjct: 101 GGGKSRTGVMIPIPQYPLYSAVISELDAIQVNYYLDEENCWALNVNELRRAVQEAKDHCD 160

Query: 208 -KTACLIVNNPSNPCGSVFSKRHLQKILAVAARQCVPILADEIYGDMVFS-DCK------ 259
            K  C+I  NP NP G V S++ ++ ++  A  + + +LADE+Y D V+S DC+      
Sbjct: 161 PKVLCII--NPGNPTGQVQSRKCIEDVIHFAWEEKLFLLADEVYQDNVYSPDCRFHSFKK 218

Query: 260 --YEPLATLSTDVPILSCGGLAKRWLVP-GWRLGWILIHDRRDIFGNEIRDGLVKLSQRI 316
             YE     S++V + S    +K ++   G+R G++ + +       EI+  LVKL    
Sbjct: 219 VLYEMGPEYSSNVELASFHSTSKGYMGECGYRGGYMEVINLHP----EIKGQLVKLLSVR 274

Query: 317 LGPCTIVQGALKSILCRTP----------GEFYHNTLSFLKSNADLCYGALAAIPGLRPV 366
           L P    Q A+  I+   P               + L  L   A L       +PG+   
Sbjct: 275 LCPPVSGQAAM-DIVVNPPVAGEESFEQFSREKESVLGNLAKKAKLTEDLFNQVPGIHCN 333

Query: 367 RPSGAMYLM-------VGIEMEHFPEFENDVEFTERLVAEQSVHCLPATCF---EYPNFI 416
              GAMY           +E     +   D+ +  +L+ E  +  +P + F   E     
Sbjct: 334 PLQGAMYAFPRIFIPAKAVEAAQAHQMAPDMFYCMKLLEETGICVVPGSGFGQREGTYHF 393

Query: 417 RVVITVPEVMMLEACSRIQEF 437
           R+ I  P   +     ++++F
Sbjct: 394 RMTILPPVEKLKTVLQKVKDF 414


>gi|19263340 glutamic pyruvate transaminase 2 isoform 1 [Homo
           sapiens]
          Length = 523

 Score = 82.0 bits (201), Expect = 1e-15
 Identities = 90/381 (23%), Positives = 157/381 (41%), Gaps = 50/381 (13%)

Query: 100 ALDSGKYNGYAPSIGFLSSREEIASYYHCPEA--PLEAKDVILTSGCSQAIDLCLAVLAN 157
           A        Y+ S G    RE++A+Y    +   P +  ++ LT+G S  I   L +L +
Sbjct: 141 ACGGNSLGSYSASQGVNCIREDVAAYITRRDGGVPADPDNIYLTTGASDGISTILKILVS 200

Query: 158 PG----QNILVPRPGFSLYKTLAESMGIEVKLYNLLPEKSWEIDLKQLEYLIDE------ 207
            G      +++P P + LY  +   +      Y L  E  W +++ +L   + E      
Sbjct: 201 GGGKSRTGVMIPIPQYPLYSAVISELDAIQVNYYLDEENCWALNVNELRRAVQEAKDHCD 260

Query: 208 -KTACLIVNNPSNPCGSVFSKRHLQKILAVAARQCVPILADEIYGDMVFS-DCK------ 259
            K  C+I  NP NP G V S++ ++ ++  A  + + +LADE+Y D V+S DC+      
Sbjct: 261 PKVLCII--NPGNPTGQVQSRKCIEDVIHFAWEEKLFLLADEVYQDNVYSPDCRFHSFKK 318

Query: 260 --YEPLATLSTDVPILSCGGLAKRWLVP-GWRLGWILIHDRRDIFGNEIRDGLVKLSQRI 316
             YE     S++V + S    +K ++   G+R G++ + +       EI+  LVKL    
Sbjct: 319 VLYEMGPEYSSNVELASFHSTSKGYMGECGYRGGYMEVINLHP----EIKGQLVKLLSVR 374

Query: 317 LGPCTIVQGALKSILCRTP----------GEFYHNTLSFLKSNADLCYGALAAIPGLRPV 366
           L P    Q A+  I+   P               + L  L   A L       +PG+   
Sbjct: 375 LCPPVSGQAAM-DIVVNPPVAGEESFEQFSREKESVLGNLAKKAKLTEDLFNQVPGIHCN 433

Query: 367 RPSGAMYLM-------VGIEMEHFPEFENDVEFTERLVAEQSVHCLPATCF---EYPNFI 416
              GAMY           +E     +   D+ +  +L+ E  +  +P + F   E     
Sbjct: 434 PLQGAMYAFPRIFIPAKAVEAAQAHQMAPDMFYCMKLLEETGICVVPGSGFGQREGTYHF 493

Query: 417 RVVITVPEVMMLEACSRIQEF 437
           R+ I  P   +     ++++F
Sbjct: 494 RMTILPPVEKLKTVLQKVKDF 514


>gi|56713254 kynurenine aminotransferase III isoform 1 [Homo
           sapiens]
          Length = 454

 Score = 79.0 bits (193), Expect = 8e-15
 Identities = 68/298 (22%), Positives = 129/298 (43%), Gaps = 31/298 (10%)

Query: 136 KDVILTSGCSQAIDLCLAVLANPGQNILVPRPGFSLYKTLAESMGIEVKLYNLLPE---- 191
           K++++T G   ++   +  L + G  +++  P +  Y+ +    G       L  +    
Sbjct: 126 KEILVTVGAYGSLFNTIQALIDEGDEVILIVPFYDCYEPMVRMAGATPVFIPLRSKPVYG 185

Query: 192 -----KSWEIDLKQLEYLIDEKTACLIVNNPSNPCGSVFSKRHLQKILAVAARQCVPILA 246
                  W +D ++LE   + KT  +I+N P NP G V+++  LQ I  +  +     ++
Sbjct: 186 KRWSSSDWTLDPQELESKFNSKTKAIILNTPHNPLGKVYNREELQVIADLCIKYDTLCIS 245

Query: 247 DEIYGDMVFSDCKYEPLATL-STDVPILSCGGLAKRWLVPGWRLGWILIHDRRDIFGNEI 305
           DE+Y  +V+S  K+  +AT        ++ G   K + V GW+LGW        I  N +
Sbjct: 246 DEVYEWLVYSGNKHLKIATFPGMWERTITIGSAGKTFSVTGWKLGW-------SIGPNHL 298

Query: 306 RDGLVKLSQRILGPC-TIVQGALK-----SILCRTPGEFYHNTL-SFLKSNADLCYGALA 358
              L  + Q  +  C T +Q AL       I      E Y N+L   L+   D     L 
Sbjct: 299 IKHLQTVQQNTIYTCATPLQEALAQAFWIDIKRMDDPECYFNSLPKELEVKRDRMVRLLE 358

Query: 359 AIPGLRPVRPSGAMYLMVGIEM--EHFPEFEN----DVEFTERLVAEQSVHCLPATCF 410
           ++ GL+P+ P G  +++  + +      + +N    D +F + +   + +  +P + F
Sbjct: 359 SV-GLKPIVPDGGYFIIADVSLLDPDLSDMKNNEPYDYKFVKWMTKHKKLSAIPVSAF 415


>gi|56713256 kynurenine aminotransferase III isoform 2 [Homo
           sapiens]
          Length = 420

 Score = 79.0 bits (193), Expect = 8e-15
 Identities = 68/298 (22%), Positives = 129/298 (43%), Gaps = 31/298 (10%)

Query: 136 KDVILTSGCSQAIDLCLAVLANPGQNILVPRPGFSLYKTLAESMGIEVKLYNLLPE---- 191
           K++++T G   ++   +  L + G  +++  P +  Y+ +    G       L  +    
Sbjct: 92  KEILVTVGAYGSLFNTIQALIDEGDEVILIVPFYDCYEPMVRMAGATPVFIPLRSKPVYG 151

Query: 192 -----KSWEIDLKQLEYLIDEKTACLIVNNPSNPCGSVFSKRHLQKILAVAARQCVPILA 246
                  W +D ++LE   + KT  +I+N P NP G V+++  LQ I  +  +     ++
Sbjct: 152 KRWSSSDWTLDPQELESKFNSKTKAIILNTPHNPLGKVYNREELQVIADLCIKYDTLCIS 211

Query: 247 DEIYGDMVFSDCKYEPLATL-STDVPILSCGGLAKRWLVPGWRLGWILIHDRRDIFGNEI 305
           DE+Y  +V+S  K+  +AT        ++ G   K + V GW+LGW        I  N +
Sbjct: 212 DEVYEWLVYSGNKHLKIATFPGMWERTITIGSAGKTFSVTGWKLGW-------SIGPNHL 264

Query: 306 RDGLVKLSQRILGPC-TIVQGALK-----SILCRTPGEFYHNTL-SFLKSNADLCYGALA 358
              L  + Q  +  C T +Q AL       I      E Y N+L   L+   D     L 
Sbjct: 265 IKHLQTVQQNTIYTCATPLQEALAQAFWIDIKRMDDPECYFNSLPKELEVKRDRMVRLLE 324

Query: 359 AIPGLRPVRPSGAMYLMVGIEM--EHFPEFEN----DVEFTERLVAEQSVHCLPATCF 410
           ++ GL+P+ P G  +++  + +      + +N    D +F + +   + +  +P + F
Sbjct: 325 SV-GLKPIVPDGGYFIIADVSLLDPDLSDMKNNEPYDYKFVKWMTKHKKLSAIPVSAF 381


>gi|169881281 kynurenine aminotransferase I isoform b [Homo sapiens]
          Length = 372

 Score = 73.6 bits (179), Expect = 4e-13
 Identities = 62/275 (22%), Positives = 120/275 (43%), Gaps = 34/275 (12%)

Query: 162 ILVPRPGFSLYKTLAESMGIEVKLYNLLP----------EKSWEIDLKQLEYLIDEKTAC 211
           +++  P F  Y+ +    G      +L P            +W++D  +L      +T  
Sbjct: 68  VIIIEPFFDCYEPMTMMAGGRPVFVSLKPGPIQNGELGSSSNWQLDPMELAGKFTSRTKA 127

Query: 212 LIVNNPSNPCGSVFSKRHLQKILAVAARQCVPILADEIYGDMVFSDCKYEPLATL-STDV 270
           L++N P+NP G VFS+  L+ + ++  +  V  + DE+Y  MV+   ++  +A+L     
Sbjct: 128 LVLNTPNNPLGKVFSREELELVASLCQQHDVVCITDEVYQWMVYDGHQHISIASLPGMWE 187

Query: 271 PILSCGGLAKRWLVPGWRLGWILIHDRRDIFGNEIRDGLVKLSQRILGPC-TIVQGAL-- 327
             L+ G   K +   GW++GW+L  D        I   L  + Q  +  C T  Q A+  
Sbjct: 188 RTLTIGSAGKTFSATGWKVGWVLGPD-------HIMKHLRTVHQNSVFHCPTQSQAAVAE 240

Query: 328 ----KSILCRTPGEFYHNTLSFLKSNADLCYGALAAIPGLRPVRPSGAMYLMVGI----- 378
               + +L R P  ++      ++   D    +L ++ GL+P+ P G+ +L+  I     
Sbjct: 241 SFEREQLLFRQPSSYFVQFPQAMQRCRDHMIRSLQSV-GLKPIIPQGSYFLITDISDFKR 299

Query: 379 EMEHFP---EFENDVEFTERLVAEQSVHCLPATCF 410
           +M   P   +   D  F + ++  + +  +P + F
Sbjct: 300 KMPDLPGAVDEPYDRRFVKWMIKNKGLVAIPVSIF 334


>gi|4885351 glutamic pyruvate transaminase [Homo sapiens]
          Length = 496

 Score = 70.9 bits (172), Expect = 2e-12
 Identities = 54/184 (29%), Positives = 91/184 (49%), Gaps = 14/184 (7%)

Query: 86  NLPTDPEV-TQAMKDALDSGKYNGYAPSIGFLSSREEIASYYHCPEA--PLEAKDVILTS 142
           N P D +   + +  A        Y+ S G    RE++A Y    +   P +  +V L++
Sbjct: 99  NFPDDAKKRAERILQACGGHSLGAYSVSSGIQLIREDVARYIERRDGGIPADPNNVFLST 158

Query: 143 GCSQAIDLCLAVL-ANPGQN---ILVPRPGFSLYK-TLAESMGIEVKLYNLLPEKSWEID 197
           G S AI   L +L A  G     +L+P P + LY  TLAE   ++V  Y L  E++W +D
Sbjct: 159 GASDAIVTVLKLLVAGEGHTRTGVLIPIPQYPLYSATLAELGAVQVDYY-LDEERAWALD 217

Query: 198 LKQLEYLIDE-----KTACLIVNNPSNPCGSVFSKRHLQKILAVAARQCVPILADEIYGD 252
           + +L   + +     +   L V NP NP G V ++  ++ ++  A  + + +LADE+Y D
Sbjct: 218 VAELHRALGQARDHCRPRALCVINPGNPTGQVQTRECIEAVIRFAFEERLFLLADEVYQD 277

Query: 253 MVFS 256
            V++
Sbjct: 278 NVYA 281


>gi|149944424 1-aminocyclopropane-1-carboxylate synthase homolog
           (Arabidopsis)(non-functional)-like [Homo sapiens]
          Length = 568

 Score = 61.6 bits (148), Expect = 1e-09
 Identities = 56/203 (27%), Positives = 94/203 (46%), Gaps = 28/203 (13%)

Query: 119 REEIASY--YHCPEAP--LEAKDVILTSGCSQAIDLCLAVLANPGQNILVPRP---GFSL 171
           REE+A +  Y+C  AP  L+ ++V++ +GC         VL +PG+  LVP P   GF+ 
Sbjct: 214 REEVARFLTYYC-RAPTRLDPENVVVLNGCCSVFCALAMVLCDPGEAFLVPAPFYGGFAF 272

Query: 172 YKTLAESMGI-------EVKLYNLLPEKSWEIDLKQLEYLIDE------KTACLIVNNPS 218
              L   + +       EV + N  P   +++ + +LE  + E      K   L++ NP 
Sbjct: 273 SSRLYAKVELIPVHLESEVTVTNTHP---FQLTVDKLEEALLEARLEGKKVRGLVLINPQ 329

Query: 219 NPCGSVFSKRHLQKILAVAARQCVPILADEIYGDMVFSDC----KYEPLATLSTDVPILS 274
           NP G ++S   L K L  A R  + ++ DEIY   VF +         + +L        
Sbjct: 330 NPLGDIYSPDSLMKYLEFAKRYNLHVIIDEIYMLSVFDESITFHSILSMKSLPDSNRTHV 389

Query: 275 CGGLAKRWLVPGWRLGWILIHDR 297
             G +K + + G+R G +  H++
Sbjct: 390 IWGTSKDFGISGFRFGALYTHNK 412


>gi|187936925 1-aminocyclopropane-1-carboxylate synthase homolog
           [Homo sapiens]
          Length = 501

 Score = 59.3 bits (142), Expect = 7e-09
 Identities = 48/165 (29%), Positives = 77/165 (46%), Gaps = 20/165 (12%)

Query: 109 YAPSIGFLSSREEIA---SYYHCPEAPLEAKDVILTSGCSQAIDLCLAVLANPGQNILVP 165
           YA   G L  REE+A   S+Y     PL  ++V++ +G +        VL   G+  L+P
Sbjct: 132 YADWRGHLFLREEVAKFLSFYCKSPVPLRPENVVVLNGGASLFSALATVLCEAGEAFLIP 191

Query: 166 RPGFS-------LYKTL--------AESMGIEVKLYNLLPEKSWEIDLKQLEYLIDEKTA 210
            P +        LY  +        +E  G++ + + L  EK  E+ L++  +    K  
Sbjct: 192 TPYYGAITQHVCLYGNIRLAYVYLDSEVTGLDTRPFQLTVEKL-EMALREA-HSEGVKVK 249

Query: 211 CLIVNNPSNPCGSVFSKRHLQKILAVAARQCVPILADEIYGDMVF 255
            LI+ +P NP G V+S   LQ+ L  A R  + ++ DE+Y   VF
Sbjct: 250 GLILISPQNPLGDVYSPEELQEYLVFAKRHRLHVIVDEVYMLSVF 294


>gi|14211921 1-aminocyclopropane-1-carboxylate synthase homolog
           [Homo sapiens]
          Length = 501

 Score = 59.3 bits (142), Expect = 7e-09
 Identities = 48/165 (29%), Positives = 77/165 (46%), Gaps = 20/165 (12%)

Query: 109 YAPSIGFLSSREEIA---SYYHCPEAPLEAKDVILTSGCSQAIDLCLAVLANPGQNILVP 165
           YA   G L  REE+A   S+Y     PL  ++V++ +G +        VL   G+  L+P
Sbjct: 132 YADWRGHLFLREEVAKFLSFYCKSPVPLRPENVVVLNGGASLFSALATVLCEAGEAFLIP 191

Query: 166 RPGFS-------LYKTL--------AESMGIEVKLYNLLPEKSWEIDLKQLEYLIDEKTA 210
            P +        LY  +        +E  G++ + + L  EK  E+ L++  +    K  
Sbjct: 192 TPYYGAITQHVCLYGNIRLAYVYLDSEVTGLDTRPFQLTVEKL-EMALREA-HSEGVKVK 249

Query: 211 CLIVNNPSNPCGSVFSKRHLQKILAVAARQCVPILADEIYGDMVF 255
            LI+ +P NP G V+S   LQ+ L  A R  + ++ DE+Y   VF
Sbjct: 250 GLILISPQNPLGDVYSPEELQEYLVFAKRHRLHVIVDEVYMLSVF 294


>gi|7705897 kynurenine aminotransferase II [Homo sapiens]
          Length = 425

 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 63/275 (22%), Positives = 114/275 (41%), Gaps = 43/275 (15%)

Query: 49  AKKTFNPIRAIVDNMKVKPNPNKTMISLSIG--DPTVFG---------NLPTDPEVTQAM 97
           A +  +PIR + D +   P   K+MISL+ G  +P +F          N  T     + M
Sbjct: 12  AARNPSPIRTMTDILSRGP---KSMISLAGGLPNPNMFPFKTAVITVENGKTIQFGEEMM 68

Query: 98  KDALDSGKYNGYAPSIGF---LSSREEIASYYHCPEA----PLEAK-DVILTSGCSQAID 149
           K AL       Y+PS G    LS  +++    H P      P + + D+ +TSG  Q + 
Sbjct: 69  KRALQ------YSPSAGIPELLSWLKQLQIKLHNPPTIHYPPSQGQMDLCVTSGSQQGLC 122

Query: 150 LCLAVLANPGQNILVPRPGFSLYKTLAESMGIEVKLYNLLPEKSWEIDLKQLEYLIDEKT 209
               ++ NPG N+L+  P +S   TL     +   + N+  ++S  +     + L   K 
Sbjct: 123 KVFEMIINPGDNVLLDEPAYS--GTLQSLHPLGCNIINVASDESGIVPDSLRDILSRWKP 180

Query: 210 A------------CLIVNNPSNPCGSVFSKRHLQKILAVAARQCVPILADEIYGDMVFSD 257
                           V N +NP G+  +    ++I  +A +    I+ D+ Y  + F+ 
Sbjct: 181 EDAKNPQKNTPKFLYTVPNGNNPTGNSLTSERKKEIYELARKYDFLIIEDDPYYFLQFNK 240

Query: 258 CKYEPLATLSTDVPILSCGGLAKRWLVPGWRLGWI 292
            +     ++  D  ++     +K  +  G R+G++
Sbjct: 241 FRVPTFLSMDVDGRVIRADSFSK-IISSGLRIGFL 274


>gi|33469970 kynurenine aminotransferase II [Homo sapiens]
          Length = 425

 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 63/275 (22%), Positives = 114/275 (41%), Gaps = 43/275 (15%)

Query: 49  AKKTFNPIRAIVDNMKVKPNPNKTMISLSIG--DPTVFG---------NLPTDPEVTQAM 97
           A +  +PIR + D +   P   K+MISL+ G  +P +F          N  T     + M
Sbjct: 12  AARNPSPIRTMTDILSRGP---KSMISLAGGLPNPNMFPFKTAVITVENGKTIQFGEEMM 68

Query: 98  KDALDSGKYNGYAPSIGF---LSSREEIASYYHCPEA----PLEAK-DVILTSGCSQAID 149
           K AL       Y+PS G    LS  +++    H P      P + + D+ +TSG  Q + 
Sbjct: 69  KRALQ------YSPSAGIPELLSWLKQLQIKLHNPPTIHYPPSQGQMDLCVTSGSQQGLC 122

Query: 150 LCLAVLANPGQNILVPRPGFSLYKTLAESMGIEVKLYNLLPEKSWEIDLKQLEYLIDEKT 209
               ++ NPG N+L+  P +S   TL     +   + N+  ++S  +     + L   K 
Sbjct: 123 KVFEMIINPGDNVLLDEPAYS--GTLQSLHPLGCNIINVASDESGIVPDSLRDILSRWKP 180

Query: 210 A------------CLIVNNPSNPCGSVFSKRHLQKILAVAARQCVPILADEIYGDMVFSD 257
                           V N +NP G+  +    ++I  +A +    I+ D+ Y  + F+ 
Sbjct: 181 EDAKNPQKNTPKFLYTVPNGNNPTGNSLTSERKKEIYELARKYDFLIIEDDPYYFLQFNK 240

Query: 258 CKYEPLATLSTDVPILSCGGLAKRWLVPGWRLGWI 292
            +     ++  D  ++     +K  +  G R+G++
Sbjct: 241 FRVPTFLSMDVDGRVIRADSFSK-IISSGLRIGFL 274


>gi|153792230 hypothetical protein LOC57670 [Homo sapiens]
          Length = 1884

 Score = 32.0 bits (71), Expect = 1.2
 Identities = 26/100 (26%), Positives = 43/100 (43%), Gaps = 7/100 (7%)

Query: 26  GRSSVPGKMKGRK-----ARWSVRPSDMAKKTFNPIRAIVDNMKVKPNPNKTMISLSIGD 80
           GR SVP  +         A   V PS +    F+ I +I+ +       NK   SL++ D
Sbjct: 476 GRLSVPASLDPTAGSLSVAETQVTPSSVTTAFFSVITSILLDSSFSVIANKNTPSLAVRD 535

Query: 81  PTVFGNLPTDPEVTQAMKDALDSGKYNGYAP--SIGFLSS 118
           P+VF      P V  ++    +   ++ + P  ++ F SS
Sbjct: 536 PSVFTPYSLVPSVESSLFSDQERSSFSEHKPRGALDFASS 575


>gi|148596944 C2 calcium-dependent domain containing 3 [Homo sapiens]
          Length = 1963

 Score = 32.0 bits (71), Expect = 1.2
 Identities = 33/132 (25%), Positives = 52/132 (39%), Gaps = 25/132 (18%)

Query: 310  VKLSQRILGPCTIVQGALKSILCRTPGEFYHNTLSFLKSNADLCYGALAAIPGLRPVRPS 369
            V +S +I+  C + Q A K++  R P   +  T+           G  A++       P 
Sbjct: 1197 VSISVQIIRACGL-QAAAKALAEREPALQFSATV-----------GVNASVTTHLSFLPQ 1244

Query: 370  GAMYLMVGIEMEHFPEFENDVEFTERLVAEQSVHCLPATCF--EYPNFIRVVITV----- 422
            G       +     PEF + VEFT  LV +   HC    CF  E   F  V+  V     
Sbjct: 1245 GEQRRTHPVACSFCPEFSHHVEFTCNLVTQ---HCSGEACFLAELLEFAEVIFAVYHENT 1301

Query: 423  ---PEVMMLEAC 431
                +++ +E+C
Sbjct: 1302 KSASDIISIESC 1313


>gi|23503267 ectonucleotide pyrophosphatase/phosphodiesterase 6
           [Homo sapiens]
          Length = 440

 Score = 32.0 bits (71), Expect = 1.2
 Identities = 20/62 (32%), Positives = 32/62 (51%), Gaps = 6/62 (9%)

Query: 84  FGNLPTDPEVTQAMKDALDSGKYNGYAPSIGFLSSREEIASYYHCPEAP-----LEAKDV 138
           + N+PTD     A+ DALDS K +G A        R ++  +++ P +P     L+A D 
Sbjct: 157 YKNVPTDINFANAVSDALDSFK-SGRADLAAIYHERIDVEGHHYGPASPQRKDALKAVDT 215

Query: 139 IL 140
           +L
Sbjct: 216 VL 217


>gi|37595528 polyhomeotic-like 2 isoform a [Homo sapiens]
          Length = 858

 Score = 31.6 bits (70), Expect = 1.6
 Identities = 18/59 (30%), Positives = 27/59 (45%)

Query: 12  GNLPSILDVHVNVGGRSSVPGKMKGRKARWSVRPSDMAKKTFNPIRAIVDNMKVKPNPN 70
           G   S+++ H    G SSVPG M+GR       P+  A     P  A +   ++ P P+
Sbjct: 282 GIADSVMEPHKKGDGNSSVPGSMEGRAGLSRTVPAVAAHPLIAPAYAQLQPHQLLPQPS 340


>gi|28559088 laminin alpha 2 subunit isoform a precursor [Homo
            sapiens]
          Length = 3122

 Score = 31.2 bits (69), Expect = 2.0
 Identities = 41/180 (22%), Positives = 65/180 (36%), Gaps = 31/180 (17%)

Query: 17   ILDVHVNVG-----GRSSVPGKMKGRKARWSVRPSDMAKKTFNPIRAIVD-----NMKVK 66
            + D H+ V      G +SV         +W        +K  N     +D     N+   
Sbjct: 2393 LTDGHIKVSYDLGSGMASVVSNQNHNDGKWKSFTLSRIQKQANISIVDIDTNQEENIATS 2452

Query: 67   PNPNKTMISLSIGDPTVFGNLPTDPEVTQAMKDALDSGKYNGYAPSIGFLSSREEIASYY 126
             + N   + L   D   FG LPT   ++   +  ++  KY+G    I       EI+   
Sbjct: 2453 SSGNNFGLDLKADDKIYFGGLPTLRNLSMKARPEVNLKKYSGCLKDI-------EIS--- 2502

Query: 127  HCPEAPLEAKDVI-LTSGCSQAIDLCLAVLANPGQNILVPRPGFSLYKTLAESMGIEVKL 185
              P   L + D + +T GCS         L N    +  P+PGF     +   +G E+ L
Sbjct: 2503 RTPYNILSSPDYVGVTKGCS---------LENV-YTVSFPKPGFVELSPVPIDVGTEINL 2552


>gi|150456451 hypothetical protein LOC54914 [Homo sapiens]
          Length = 1801

 Score = 30.4 bits (67), Expect = 3.5
 Identities = 17/51 (33%), Positives = 28/51 (54%), Gaps = 3/51 (5%)

Query: 149  DLCLAVLANPGQNILVPRPGFSLYKTLAESMGIEVKLYNLLPEKSWEIDLK 199
            +LC + L    Q + +P P   L+  L+E+ G   K+++LLP K    DL+
Sbjct: 1504 ELCPSALHGLSQAMKLPSPAHHLWSLLSEATG---KIFDLLPNKIRRKDLE 1551


>gi|32307132 NFS1 nitrogen fixation 1 [Homo sapiens]
          Length = 457

 Score = 30.4 bits (67), Expect = 3.5
 Identities = 34/148 (22%), Positives = 63/148 (42%), Gaps = 18/148 (12%)

Query: 88  PTDPEVTQAMKDALDSGKYN--------GYAPSIGFLSSREEIASYYHCPEAPLEAKDVI 139
           P DP V  AM   L +   N        G+        +R+++AS         + +++I
Sbjct: 68  PLDPRVLDAMLPYLINYYGNPHSRTHAYGWESEAAMERARQQVASLIGA-----DPREII 122

Query: 140 LTSGCSQAIDLCLAVLA----NPGQNILVPRPGFSLYKTLAESMGIEVKLYNLLP-EKSW 194
            TSG +++ ++ +  +A    +  ++++  +           S+  E      LP +KS 
Sbjct: 123 FTSGATESNNIAIKGVARFYRSRKKHLITTQTEHKCVLDSCRSLEAEGFQVTYLPVQKSG 182

Query: 195 EIDLKQLEYLIDEKTACLIVNNPSNPCG 222
            IDLK+LE  I   T+ + V   +N  G
Sbjct: 183 IIDLKELEAAIQPDTSLVSVMTVNNEIG 210


>gi|60498973 myelin transcription factor 1-like [Homo sapiens]
          Length = 1184

 Score = 30.0 bits (66), Expect = 4.5
 Identities = 23/78 (29%), Positives = 35/78 (44%), Gaps = 9/78 (11%)

Query: 91  PEVTQAMKDALDSGKYNGYAPSIGFLSSREEIASYYHCPEAPLEAKDVILTSGCSQAIDL 150
           PE     ++AL+  +Y G    +   S + +   Y  C E+    KD+I  SGC  A   
Sbjct: 839 PEDLDPFQEALEERRYPG---EVTIPSPKPK---YPQCKESK---KDLITLSGCPLADKS 889

Query: 151 CLAVLANPGQNILVPRPG 168
             ++LA   Q +  P PG
Sbjct: 890 IRSMLATSSQELKCPTPG 907


>gi|9789865 eukaryotic translation initiation factor 4E nuclear
           import factor 1 [Homo sapiens]
          Length = 985

 Score = 29.3 bits (64), Expect = 7.7
 Identities = 19/76 (25%), Positives = 37/76 (48%), Gaps = 2/76 (2%)

Query: 30  VPGKMKGRKARWSVRPSD--MAKKTFNPIRAIVDNMKVKPNPNKTMISLSIGDPTVFGNL 87
           V   +KG K    V+ S   MA+     + A+ +N ++K + + T  +  +      G L
Sbjct: 438 VEAGLKGLKVDQQVKNSTPFMAEHLEETLSAVTNNRQLKKDGDMTAFNKLVSTMKASGTL 497

Query: 88  PTDPEVTQAMKDALDS 103
           P+ P+V++ ++  L S
Sbjct: 498 PSQPKVSRNLESHLMS 513


>gi|40254949 erythrocyte membrane protein band 4.1 like 5 [Homo
           sapiens]
          Length = 733

 Score = 29.3 bits (64), Expect = 7.7
 Identities = 66/311 (21%), Positives = 120/311 (38%), Gaps = 53/311 (17%)

Query: 6   IQMSSKGNLPSILDVHVNVGGRSSVPGKMKGRKARWSVRPSDMAKKTFNPIRAIVDNMKV 65
           +QM +    P  L VH NV  +S+   +  G ++   V PS  +     P+   ++N+  
Sbjct: 380 LQMKACATKPEELSVHNNVSTQSNGSQQAWGMRSALPVSPSISSA----PVPVEIENLPQ 435

Query: 66  KPNPNK----------------TMISLSIGDPTVFGNLPTDPEVTQAMKDALDSGKYNGY 109
            P  ++                 ++  +IGD  V G   T  E +QA+ D   + +  G 
Sbjct: 436 SPGTDQHDRKCIPLNIDLLNSPDLLEATIGD--VIGASDT-METSQALNDVNVATRLPGL 492

Query: 110 A-PSIGF--LSSREEIASYYHCPEAPLEAK----DVILTS--GCSQAIDLCL-AVLANPG 159
             P + +  L    E         +PL +     DV + S     +  + CL  V+ +PG
Sbjct: 493 GEPEVEYETLKDTSEKLKQLEMENSPLLSPRSNIDVNINSQEEVVKLTEKCLNNVIESPG 552

Query: 160 QNILVPRPGF--SLYKTLAESMGIEVKLYNLLPEKSWEIDLKQLEYLIDEKTACLIVNNP 217
            N++   P F  ++ K   E++    K  +LL  K+  +         D  T   ++N  
Sbjct: 553 LNVMRVPPDFKSNILKAQVEAVHKVTKEDSLLSHKNANVQ--------DAATNSAVLNEN 604

Query: 218 SNPCGSVFSKRHLQKILAVAARQCVPIL---ADEIYGDMVFSDCKYEPLATLSTDVPILS 274
           + P      K  L+ ++ +       +L    DE+  D + +    E L   +    + S
Sbjct: 605 NVP----LPKESLETLMLITPADSGSVLKEATDEL--DALLASLT-ENLIDHTVAPQVSS 657

Query: 275 CGGLAKRWLVP 285
              +  RW+VP
Sbjct: 658 TSMITPRWIVP 668


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.138    0.424 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,393,683
Number of Sequences: 37866
Number of extensions: 825005
Number of successful extensions: 1637
Number of sequences better than 10.0: 24
Number of HSP's better than 10.0 without gapping: 16
Number of HSP's successfully gapped in prelim test: 8
Number of HSP's that attempted gapping in prelim test: 1603
Number of HSP's gapped (non-prelim): 26
length of query: 454
length of database: 18,247,518
effective HSP length: 106
effective length of query: 348
effective length of database: 14,233,722
effective search space: 4953335256
effective search space used: 4953335256
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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