Guide to the Human Genome
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Name: SHB Sequence: fasta or formatted (509aa) NCBI GI: 106879210
Description:

Src homology 2 domain containing adaptor protein B

Referenced in:

Non-Receptor Tyrosine Kinase Pathways

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine            10.0         51           3
 C cysteine            2.6         13           3
 D aspartate           5.3         27           3
 E glutamate           5.9         30           2
 F phenylalanine       2.2         11           1
 G glycine             9.0         46           3
 H histidine           1.8          9           1
 I isoleucine          2.6         13           1
 K lysine              6.3         32           2
 L leucine             6.5         33           2
 M methionine          1.2          6           1
 N asparagine          2.4         12           1
 P proline             8.1         41           2
 Q glutamine           4.3         22           1
 R arginine            7.7         39           3
 S serine             13.0         66           6
 T threonine           3.1         16           2
 V valine              3.3         17           1
 W tryptophan          1.0          5           1
 Y tyrosine            3.9         20           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   Src homology 2 domain containing adaptor protein B ... 
SHF                   0.260   Src homology 2 domain containing F 
SHD                   0.220   Src homology 2 domain containing transforming prote...
SHE                   0.201   Src homology 2 domain containing E 
ABL2                  0.032   arg tyrosine kinase isoform c 
ABL2                  0.032   arg tyrosine kinase isoform b 
ABL2                  0.032   arg tyrosine kinase isoform e 
ABL2                  0.032   arg tyrosine kinase isoform d 
ABL2                  0.032   arg tyrosine kinase isoform a 
ABL1                  0.031   c-abl oncogene 1, receptor tyrosine kinase isoform a...
ABL1                  0.031   c-abl oncogene 1, receptor tyrosine kinase isoform b...
RASA1                 0.031   RAS p21 protein activator 1 isoform 1 
RASA1                 0.031   RAS p21 protein activator 1 isoform 2 
PLCG2                 0.028   phospholipase C, gamma 2 
SHC4                  0.027   rai-like protein 
NCK2                  0.027   NCK adaptor protein 2 isoform A 
NCK2                  0.027   NCK adaptor protein 2 isoform A 
FER                   0.027   fer (fps/fes related) tyrosine kinase 
NCK1                  0.026   NCK adaptor protein 1 
SRRM2                 0.024   splicing coactivator subunit SRm300 
PIK3R1                0.024   phosphoinositide-3-kinase, regulatory subunit 1 (alp...
PIK3R1                0.024   phosphoinositide-3-kinase, regulatory subunit 1 (alp...
PIK3R1                0.024   phosphoinositide-3-kinase, regulatory subunit 1 (alp...
GRAP2                 0.024   GRB2-related adaptor protein 2 
PIK3R3                0.024   phosphoinositide-3-kinase, regulatory subunit 3 (p5...
PIK3R3                0.024   phosphoinositide-3-kinase, regulatory subunit 3 (p5...
PTPN11                0.023   protein tyrosine phosphatase, non-receptor type 11 [...
CDC2L5                0.023   cell division cycle 2-like 5 isoform 1 
CDC2L5                0.023   cell division cycle 2-like 5 isoform 2 
SH2D3C                0.022   SH2 domain containing 3C isoform e 
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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