SHE 33569

Name: SHE	Sequence: fasta or formatted (495aa)		NCBI GI: 58219064
Description: Src homology 2 domain containing E		Referenced in: Non-Receptor Tyrosine Kinase Pathways
Composition: Amino acid Percentage Count Longest homopolymer A alanine 8.7 43 3 C cysteine 1.2 6 1 D aspartate 4.2 21 1 E glutamate 8.1 40 3 F phenylalanine 1.2 6 1 G glycine 9.3 46 5 H histidine 2.0 10 2 I isoleucine 3.2 16 2 K lysine 8.3 41 2 L leucine 7.9 39 2 M methionine 1.0 5 1 N asparagine 2.8 14 1 P proline 7.5 37 2 Q glutamine 4.4 22 2 R arginine 6.7 33 3 S serine 11.3 56 12 T threonine 4.0 20 1 V valine 3.4 17 2 W tryptophan 1.4 7 1 Y tyrosine 3.2 16 2			Comparative genomics: Search single species RefSeq proteins at NCBI H. sapiens M. musculus D. rerio C. intestinalis S. purpuratus D. melanogaster C. elegans A. thaliana S. cerevisiae E. coli W3110 A. pernix K1 Search summary Figure data Additional searches of RefSeq proteins at NCBI All Eukaryotes Bacteria Archaea Viruses Primates Mammals Vertebrates
Related human proteins: Protein Relative score Description Self-match 1.000 Src homology 2 domain containing E SHF 0.228 Src homology 2 domain containing F SHB 0.208 Src homology 2 domain containing adaptor protein B ... SHD 0.180 Src homology 2 domain containing transforming prote... ABL2 0.033 arg tyrosine kinase isoform c ABL2 0.033 arg tyrosine kinase isoform b ABL2 0.033 arg tyrosine kinase isoform e ABL2 0.033 arg tyrosine kinase isoform d ABL2 0.033 arg tyrosine kinase isoform a PLCG2 0.032 phospholipase C, gamma 2 ABL1 0.030 c-abl oncogene 1, receptor tyrosine kinase isoform a... ABL1 0.030 c-abl oncogene 1, receptor tyrosine kinase isoform b... SH2D7 0.030 SH2 domain containing 7 FER 0.029 fer (fps/fes related) tyrosine kinase NCK2 0.028 NCK adaptor protein 2 isoform A NCK2 0.028 NCK adaptor protein 2 isoform A PTK6 0.027 PTK6 protein tyrosine kinase 6 VAV3 0.026 vav 3 guanine nucleotide exchange factor isoform 2 ... VAV3 0.026 vav 3 guanine nucleotide exchange factor isoform 1 ... MATK 0.026 megakaryocyte-associated tyrosine kinase isoform c [... MATK 0.026 megakaryocyte-associated tyrosine kinase isoform b [... MATK 0.026 megakaryocyte-associated tyrosine kinase isoform a [... DACH1 0.026 dachshund homolog 1 isoform b DACH1 0.026 dachshund homolog 1 isoform a DACH1 0.026 dachshund homolog 1 isoform c FES 0.025 feline sarcoma oncogene isoform 2 FES 0.025 feline sarcoma oncogene isoform 1 SHC3 0.025 src homology 2 domain-containing transforming prote... SH2D2A 0.025 SH2 domain protein 2A isoform 4 SH2D2A 0.025 SH2 domain protein 2A isoform 3 Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.