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Search of human proteins with 4507025
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4507025 solute carrier family 4, sodium bicarbonate
cotransporter, member 4 isoform 2 [Homo sapiens]
(1035 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4507025 solute carrier family 4, sodium bicarbonate cotranspo... 2077 0.0
gi|148596928 solute carrier family 4, sodium bicarbonate cotrans... 2001 0.0
gi|197927160 solute carrier family 4, sodium bicarbonate cotrans... 1906 0.0
gi|19743827 sodium bicarbonate transporter 4 isoform c [Homo sap... 1306 0.0
gi|125987596 sodium bicarbonate transporter 4 isoform a [Homo sa... 1296 0.0
gi|90403614 solute carrier family 4, sodium bicarbonate cotransp... 1050 0.0
gi|90568034 solute carrier family 4, sodium bicarbonate cotransp... 1050 0.0
gi|155722998 solute carrier family 4, sodium bicarbonate transpo... 1050 0.0
gi|151101449 solute carrier family 4, sodium bicarbonate cotrans... 942 0.0
gi|134288865 solute carrier family 4, sodium bicarbonate cotrans... 910 0.0
gi|156071474 solute carrier family 4, anion exchanger, member 2 ... 658 0.0
gi|157671951 solute carrier family 4, anion exchanger, member 3 ... 647 0.0
gi|157671953 solute carrier family 4, anion exchanger, member 3 ... 647 0.0
gi|4507021 solute carrier family 4, anion exchanger, member 1 [H... 564 e-160
gi|14042960 solute carrier family 4 member 11 [Homo sapiens] 231 3e-60
gi|169161027 PREDICTED: hypothetical protein [Homo sapiens] 36 0.21
gi|113411962 PREDICTED: hypothetical protein [Homo sapiens] 36 0.21
gi|113403778 PREDICTED: hypothetical protein [Homo sapiens] 36 0.21
gi|24308089 chromodomain helicase DNA binding protein 5 [Homo sa... 35 0.37
gi|117553584 adaptor-related protein complex 3, delta 1 subunit ... 35 0.48
gi|117553580 adaptor-related protein complex 3, delta 1 subunit ... 35 0.48
gi|118498362 kinectin 1 isoform b [Homo sapiens] 34 0.62
gi|118498356 kinectin 1 isoform a [Homo sapiens] 34 0.62
gi|118498368 kinectin 1 isoform c [Homo sapiens] 34 0.62
gi|33620775 kinectin 1 isoform a [Homo sapiens] 34 0.62
gi|22902136 osterix [Homo sapiens] 33 1.1
gi|42718020 retinitis pigmentosa 9 [Homo sapiens] 33 1.1
gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens] 33 1.4
gi|27477111 step II splicing factor SLU7 [Homo sapiens] 33 1.8
gi|56090620 NFKB activating protein-like [Homo sapiens] 33 1.8
>gi|4507025 solute carrier family 4, sodium bicarbonate cotransporter,
member 4 isoform 2 [Homo sapiens]
Length = 1035
Score = 2077 bits (5382), Expect = 0.0
Identities = 1035/1035 (100%), Positives = 1035/1035 (100%)
Query: 1 MSTENVEGKPSNLGERGRARSSTFLRVVQPMFNHSIFTSAVSPAAERIRFILGEEDDSPA 60
MSTENVEGKPSNLGERGRARSSTFLRVVQPMFNHSIFTSAVSPAAERIRFILGEEDDSPA
Sbjct: 1 MSTENVEGKPSNLGERGRARSSTFLRVVQPMFNHSIFTSAVSPAAERIRFILGEEDDSPA 60
Query: 61 PPQLFTELDELLAVDGQEMEWKETARWIKFEEKVEQGGERWSKPHVATLSLHSLFELRTC 120
PPQLFTELDELLAVDGQEMEWKETARWIKFEEKVEQGGERWSKPHVATLSLHSLFELRTC
Sbjct: 61 PPQLFTELDELLAVDGQEMEWKETARWIKFEEKVEQGGERWSKPHVATLSLHSLFELRTC 120
Query: 121 MEKGSIMLDREASSLPQLVEMIVDHQIETGLLKPELKDKVTYTLLRKHRHQTKKSNLRSL 180
MEKGSIMLDREASSLPQLVEMIVDHQIETGLLKPELKDKVTYTLLRKHRHQTKKSNLRSL
Sbjct: 121 MEKGSIMLDREASSLPQLVEMIVDHQIETGLLKPELKDKVTYTLLRKHRHQTKKSNLRSL 180
Query: 181 ADIGKTVSSASRMFTNPDNGSPAMTHRNLTSSSLNDISDKPEKDQLKNKFMKKLPRDAEA 240
ADIGKTVSSASRMFTNPDNGSPAMTHRNLTSSSLNDISDKPEKDQLKNKFMKKLPRDAEA
Sbjct: 181 ADIGKTVSSASRMFTNPDNGSPAMTHRNLTSSSLNDISDKPEKDQLKNKFMKKLPRDAEA 240
Query: 241 SNVLVGEVDFLDTPFIAFVRLQQAVMLGALTEVPVPTRFLFILLGPKGKAKSYHEIGRAI 300
SNVLVGEVDFLDTPFIAFVRLQQAVMLGALTEVPVPTRFLFILLGPKGKAKSYHEIGRAI
Sbjct: 241 SNVLVGEVDFLDTPFIAFVRLQQAVMLGALTEVPVPTRFLFILLGPKGKAKSYHEIGRAI 300
Query: 301 ATLMSDEVFHDIAYKAKDRHDLIAGIDEFLDEVIVLPPGEWDPAIRIEPPKSLPSSDKRK 360
ATLMSDEVFHDIAYKAKDRHDLIAGIDEFLDEVIVLPPGEWDPAIRIEPPKSLPSSDKRK
Sbjct: 301 ATLMSDEVFHDIAYKAKDRHDLIAGIDEFLDEVIVLPPGEWDPAIRIEPPKSLPSSDKRK 360
Query: 361 NMYSGGENVQMNGDTPHDGGHGGGGHGDCEELQRTGRFCGGLIKDIKRKAPFFASDFYDA 420
NMYSGGENVQMNGDTPHDGGHGGGGHGDCEELQRTGRFCGGLIKDIKRKAPFFASDFYDA
Sbjct: 361 NMYSGGENVQMNGDTPHDGGHGGGGHGDCEELQRTGRFCGGLIKDIKRKAPFFASDFYDA 420
Query: 421 LNIQALSAILFIYLATVTNAITFGGLLGDATDNMQGVLESFLGTAVSGAIFCLFAGQPLT 480
LNIQALSAILFIYLATVTNAITFGGLLGDATDNMQGVLESFLGTAVSGAIFCLFAGQPLT
Sbjct: 421 LNIQALSAILFIYLATVTNAITFGGLLGDATDNMQGVLESFLGTAVSGAIFCLFAGQPLT 480
Query: 481 ILSSTGPVLVFERLLFNFSKDNNFDYLEFRLWIGLWSAFLCLILVATDASFLVQYFTRFT 540
ILSSTGPVLVFERLLFNFSKDNNFDYLEFRLWIGLWSAFLCLILVATDASFLVQYFTRFT
Sbjct: 481 ILSSTGPVLVFERLLFNFSKDNNFDYLEFRLWIGLWSAFLCLILVATDASFLVQYFTRFT 540
Query: 541 EEGFSSLISFIFIYDAFKKMIKLADYYPINSNFKVGYNTLFSCTCVPPDPANISISNDTT 600
EEGFSSLISFIFIYDAFKKMIKLADYYPINSNFKVGYNTLFSCTCVPPDPANISISNDTT
Sbjct: 541 EEGFSSLISFIFIYDAFKKMIKLADYYPINSNFKVGYNTLFSCTCVPPDPANISISNDTT 600
Query: 601 LAPEYLPTMSSTDMYHNTTFDWAFLSKKECSKYGGNLVGNNCNFVPDITLMSFILFLGTY 660
LAPEYLPTMSSTDMYHNTTFDWAFLSKKECSKYGGNLVGNNCNFVPDITLMSFILFLGTY
Sbjct: 601 LAPEYLPTMSSTDMYHNTTFDWAFLSKKECSKYGGNLVGNNCNFVPDITLMSFILFLGTY 660
Query: 661 TSSMALKKFKTSPYFPTTARKLISDFAIILSILIFCVIDALVGVDTPKLIVPSEFKPTSP 720
TSSMALKKFKTSPYFPTTARKLISDFAIILSILIFCVIDALVGVDTPKLIVPSEFKPTSP
Sbjct: 661 TSSMALKKFKTSPYFPTTARKLISDFAIILSILIFCVIDALVGVDTPKLIVPSEFKPTSP 720
Query: 721 NRGWFVPPFGENPWWVCLAAAIPALLVTILIFMDQQITAVIVNRKEHKLKKGAGYHLDLF 780
NRGWFVPPFGENPWWVCLAAAIPALLVTILIFMDQQITAVIVNRKEHKLKKGAGYHLDLF
Sbjct: 721 NRGWFVPPFGENPWWVCLAAAIPALLVTILIFMDQQITAVIVNRKEHKLKKGAGYHLDLF 780
Query: 781 WVAILMVICSLMALPWYVAATVISIAHIDSLKMETETSAPGEQPKFLGVREQRVTGTLVF 840
WVAILMVICSLMALPWYVAATVISIAHIDSLKMETETSAPGEQPKFLGVREQRVTGTLVF
Sbjct: 781 WVAILMVICSLMALPWYVAATVISIAHIDSLKMETETSAPGEQPKFLGVREQRVTGTLVF 840
Query: 841 ILTGLSVFMAPILKFIPMPVLYGVFLYMGVASLNGVQFMDRLKLLLMPLKHQPDFIYLRH 900
ILTGLSVFMAPILKFIPMPVLYGVFLYMGVASLNGVQFMDRLKLLLMPLKHQPDFIYLRH
Sbjct: 841 ILTGLSVFMAPILKFIPMPVLYGVFLYMGVASLNGVQFMDRLKLLLMPLKHQPDFIYLRH 900
Query: 901 VPLRRVHLFTFLQVLCLALLWILKSTVAAIIFPVMILALVAVRKGMDYLFSQHDLSFLDD 960
VPLRRVHLFTFLQVLCLALLWILKSTVAAIIFPVMILALVAVRKGMDYLFSQHDLSFLDD
Sbjct: 901 VPLRRVHLFTFLQVLCLALLWILKSTVAAIIFPVMILALVAVRKGMDYLFSQHDLSFLDD 960
Query: 961 VIPEKDKKKKEDEKKKKKKKGSLDSDNDDSDCPYSEKVPSIKIPMDIMEQQPFLSDSKPS 1020
VIPEKDKKKKEDEKKKKKKKGSLDSDNDDSDCPYSEKVPSIKIPMDIMEQQPFLSDSKPS
Sbjct: 961 VIPEKDKKKKEDEKKKKKKKGSLDSDNDDSDCPYSEKVPSIKIPMDIMEQQPFLSDSKPS 1020
Query: 1021 DRERSPTFLERHTSC 1035
DRERSPTFLERHTSC
Sbjct: 1021 DRERSPTFLERHTSC 1035
>gi|148596928 solute carrier family 4, sodium bicarbonate
cotransporter, member 4 isoform 1 [Homo sapiens]
Length = 1079
Score = 2001 bits (5184), Expect = 0.0
Identities = 996/1001 (99%), Positives = 997/1001 (99%)
Query: 35 SIFTSAVSPAAERIRFILGEEDDSPAPPQLFTELDELLAVDGQEMEWKETARWIKFEEKV 94
SI +SPAAERIRFILGEEDDSPAPPQLFTELDELLAVDGQEMEWKETARWIKFEEKV
Sbjct: 79 SILKPLISPAAERIRFILGEEDDSPAPPQLFTELDELLAVDGQEMEWKETARWIKFEEKV 138
Query: 95 EQGGERWSKPHVATLSLHSLFELRTCMEKGSIMLDREASSLPQLVEMIVDHQIETGLLKP 154
EQGGERWSKPHVATLSLHSLFELRTCMEKGSIMLDREASSLPQLVEMIVDHQIETGLLKP
Sbjct: 139 EQGGERWSKPHVATLSLHSLFELRTCMEKGSIMLDREASSLPQLVEMIVDHQIETGLLKP 198
Query: 155 ELKDKVTYTLLRKHRHQTKKSNLRSLADIGKTVSSASRMFTNPDNGSPAMTHRNLTSSSL 214
ELKDKVTYTLLRKHRHQTKKSNLRSLADIGKTVSSASRMFTNPDNGSPAMTHRNLTSSSL
Sbjct: 199 ELKDKVTYTLLRKHRHQTKKSNLRSLADIGKTVSSASRMFTNPDNGSPAMTHRNLTSSSL 258
Query: 215 NDISDKPEKDQLKNKFMKKLPRDAEASNVLVGEVDFLDTPFIAFVRLQQAVMLGALTEVP 274
NDISDKPEKDQLKNKFMKKLPRDAEASNVLVGEVDFLDTPFIAFVRLQQAVMLGALTEVP
Sbjct: 259 NDISDKPEKDQLKNKFMKKLPRDAEASNVLVGEVDFLDTPFIAFVRLQQAVMLGALTEVP 318
Query: 275 VPTRFLFILLGPKGKAKSYHEIGRAIATLMSDEVFHDIAYKAKDRHDLIAGIDEFLDEVI 334
VPTRFLFILLGPKGKAKSYHEIGRAIATLMSDEVFHDIAYKAKDRHDLIAGIDEFLDEVI
Sbjct: 319 VPTRFLFILLGPKGKAKSYHEIGRAIATLMSDEVFHDIAYKAKDRHDLIAGIDEFLDEVI 378
Query: 335 VLPPGEWDPAIRIEPPKSLPSSDKRKNMYSGGENVQMNGDTPHDGGHGGGGHGDCEELQR 394
VLPPGEWDPAIRIEPPKSLPSSDKRKNMYSGGENVQMNGDTPHDGGHGGGGHGDCEELQR
Sbjct: 379 VLPPGEWDPAIRIEPPKSLPSSDKRKNMYSGGENVQMNGDTPHDGGHGGGGHGDCEELQR 438
Query: 395 TGRFCGGLIKDIKRKAPFFASDFYDALNIQALSAILFIYLATVTNAITFGGLLGDATDNM 454
TGRFCGGLIKDIKRKAPFFASDFYDALNIQALSAILFIYLATVTNAITFGGLLGDATDNM
Sbjct: 439 TGRFCGGLIKDIKRKAPFFASDFYDALNIQALSAILFIYLATVTNAITFGGLLGDATDNM 498
Query: 455 QGVLESFLGTAVSGAIFCLFAGQPLTILSSTGPVLVFERLLFNFSKDNNFDYLEFRLWIG 514
QGVLESFLGTAVSGAIFCLFAGQPLTILSSTGPVLVFERLLFNFSKDNNFDYLEFRLWIG
Sbjct: 499 QGVLESFLGTAVSGAIFCLFAGQPLTILSSTGPVLVFERLLFNFSKDNNFDYLEFRLWIG 558
Query: 515 LWSAFLCLILVATDASFLVQYFTRFTEEGFSSLISFIFIYDAFKKMIKLADYYPINSNFK 574
LWSAFLCLILVATDASFLVQYFTRFTEEGFSSLISFIFIYDAFKKMIKLADYYPINSNFK
Sbjct: 559 LWSAFLCLILVATDASFLVQYFTRFTEEGFSSLISFIFIYDAFKKMIKLADYYPINSNFK 618
Query: 575 VGYNTLFSCTCVPPDPANISISNDTTLAPEYLPTMSSTDMYHNTTFDWAFLSKKECSKYG 634
VGYNTLFSCTCVPPDPANISISNDTTLAPEYLPTMSSTDMYHNTTFDWAFLSKKECSKYG
Sbjct: 619 VGYNTLFSCTCVPPDPANISISNDTTLAPEYLPTMSSTDMYHNTTFDWAFLSKKECSKYG 678
Query: 635 GNLVGNNCNFVPDITLMSFILFLGTYTSSMALKKFKTSPYFPTTARKLISDFAIILSILI 694
GNLVGNNCNFVPDITLMSFILFLGTYTSSMALKKFKTSPYFPTTARKLISDFAIILSILI
Sbjct: 679 GNLVGNNCNFVPDITLMSFILFLGTYTSSMALKKFKTSPYFPTTARKLISDFAIILSILI 738
Query: 695 FCVIDALVGVDTPKLIVPSEFKPTSPNRGWFVPPFGENPWWVCLAAAIPALLVTILIFMD 754
FCVIDALVGVDTPKLIVPSEFKPTSPNRGWFVPPFGENPWWVCLAAAIPALLVTILIFMD
Sbjct: 739 FCVIDALVGVDTPKLIVPSEFKPTSPNRGWFVPPFGENPWWVCLAAAIPALLVTILIFMD 798
Query: 755 QQITAVIVNRKEHKLKKGAGYHLDLFWVAILMVICSLMALPWYVAATVISIAHIDSLKME 814
QQITAVIVNRKEHKLKKGAGYHLDLFWVAILMVICSLMALPWYVAATVISIAHIDSLKME
Sbjct: 799 QQITAVIVNRKEHKLKKGAGYHLDLFWVAILMVICSLMALPWYVAATVISIAHIDSLKME 858
Query: 815 TETSAPGEQPKFLGVREQRVTGTLVFILTGLSVFMAPILKFIPMPVLYGVFLYMGVASLN 874
TETSAPGEQPKFLGVREQRVTGTLVFILTGLSVFMAPILKFIPMPVLYGVFLYMGVASLN
Sbjct: 859 TETSAPGEQPKFLGVREQRVTGTLVFILTGLSVFMAPILKFIPMPVLYGVFLYMGVASLN 918
Query: 875 GVQFMDRLKLLLMPLKHQPDFIYLRHVPLRRVHLFTFLQVLCLALLWILKSTVAAIIFPV 934
GVQFMDRLKLLLMPLKHQPDFIYLRHVPLRRVHLFTFLQVLCLALLWILKSTVAAIIFPV
Sbjct: 919 GVQFMDRLKLLLMPLKHQPDFIYLRHVPLRRVHLFTFLQVLCLALLWILKSTVAAIIFPV 978
Query: 935 MILALVAVRKGMDYLFSQHDLSFLDDVIPEKDKKKKEDEKKKKKKKGSLDSDNDDSDCPY 994
MILALVAVRKGMDYLFSQHDLSFLDDVIPEKDKKKKEDEKKKKKKKGSLDSDNDDSDCPY
Sbjct: 979 MILALVAVRKGMDYLFSQHDLSFLDDVIPEKDKKKKEDEKKKKKKKGSLDSDNDDSDCPY 1038
Query: 995 SEKVPSIKIPMDIMEQQPFLSDSKPSDRERSPTFLERHTSC 1035
SEKVPSIKIPMDIMEQQPFLSDSKPSDRERSPTFLERHTSC
Sbjct: 1039 SEKVPSIKIPMDIMEQQPFLSDSKPSDRERSPTFLERHTSC 1079
>gi|197927160 solute carrier family 4, sodium bicarbonate
cotransporter, member 4 isoform 3 [Homo sapiens]
Length = 1094
Score = 1906 bits (4937), Expect = 0.0
Identities = 950/955 (99%), Positives = 951/955 (99%)
Query: 35 SIFTSAVSPAAERIRFILGEEDDSPAPPQLFTELDELLAVDGQEMEWKETARWIKFEEKV 94
SI +SPAAERIRFILGEEDDSPAPPQLFTELDELLAVDGQEMEWKETARWIKFEEKV
Sbjct: 79 SILKPLISPAAERIRFILGEEDDSPAPPQLFTELDELLAVDGQEMEWKETARWIKFEEKV 138
Query: 95 EQGGERWSKPHVATLSLHSLFELRTCMEKGSIMLDREASSLPQLVEMIVDHQIETGLLKP 154
EQGGERWSKPHVATLSLHSLFELRTCMEKGSIMLDREASSLPQLVEMIVDHQIETGLLKP
Sbjct: 139 EQGGERWSKPHVATLSLHSLFELRTCMEKGSIMLDREASSLPQLVEMIVDHQIETGLLKP 198
Query: 155 ELKDKVTYTLLRKHRHQTKKSNLRSLADIGKTVSSASRMFTNPDNGSPAMTHRNLTSSSL 214
ELKDKVTYTLLRKHRHQTKKSNLRSLADIGKTVSSASRMFTNPDNGSPAMTHRNLTSSSL
Sbjct: 199 ELKDKVTYTLLRKHRHQTKKSNLRSLADIGKTVSSASRMFTNPDNGSPAMTHRNLTSSSL 258
Query: 215 NDISDKPEKDQLKNKFMKKLPRDAEASNVLVGEVDFLDTPFIAFVRLQQAVMLGALTEVP 274
NDISDKPEKDQLKNKFMKKLPRDAEASNVLVGEVDFLDTPFIAFVRLQQAVMLGALTEVP
Sbjct: 259 NDISDKPEKDQLKNKFMKKLPRDAEASNVLVGEVDFLDTPFIAFVRLQQAVMLGALTEVP 318
Query: 275 VPTRFLFILLGPKGKAKSYHEIGRAIATLMSDEVFHDIAYKAKDRHDLIAGIDEFLDEVI 334
VPTRFLFILLGPKGKAKSYHEIGRAIATLMSDEVFHDIAYKAKDRHDLIAGIDEFLDEVI
Sbjct: 319 VPTRFLFILLGPKGKAKSYHEIGRAIATLMSDEVFHDIAYKAKDRHDLIAGIDEFLDEVI 378
Query: 335 VLPPGEWDPAIRIEPPKSLPSSDKRKNMYSGGENVQMNGDTPHDGGHGGGGHGDCEELQR 394
VLPPGEWDPAIRIEPPKSLPSSDKRKNMYSGGENVQMNGDTPHDGGHGGGGHGDCEELQR
Sbjct: 379 VLPPGEWDPAIRIEPPKSLPSSDKRKNMYSGGENVQMNGDTPHDGGHGGGGHGDCEELQR 438
Query: 395 TGRFCGGLIKDIKRKAPFFASDFYDALNIQALSAILFIYLATVTNAITFGGLLGDATDNM 454
TGRFCGGLIKDIKRKAPFFASDFYDALNIQALSAILFIYLATVTNAITFGGLLGDATDNM
Sbjct: 439 TGRFCGGLIKDIKRKAPFFASDFYDALNIQALSAILFIYLATVTNAITFGGLLGDATDNM 498
Query: 455 QGVLESFLGTAVSGAIFCLFAGQPLTILSSTGPVLVFERLLFNFSKDNNFDYLEFRLWIG 514
QGVLESFLGTAVSGAIFCLFAGQPLTILSSTGPVLVFERLLFNFSKDNNFDYLEFRLWIG
Sbjct: 499 QGVLESFLGTAVSGAIFCLFAGQPLTILSSTGPVLVFERLLFNFSKDNNFDYLEFRLWIG 558
Query: 515 LWSAFLCLILVATDASFLVQYFTRFTEEGFSSLISFIFIYDAFKKMIKLADYYPINSNFK 574
LWSAFLCLILVATDASFLVQYFTRFTEEGFSSLISFIFIYDAFKKMIKLADYYPINSNFK
Sbjct: 559 LWSAFLCLILVATDASFLVQYFTRFTEEGFSSLISFIFIYDAFKKMIKLADYYPINSNFK 618
Query: 575 VGYNTLFSCTCVPPDPANISISNDTTLAPEYLPTMSSTDMYHNTTFDWAFLSKKECSKYG 634
VGYNTLFSCTCVPPDPANISISNDTTLAPEYLPTMSSTDMYHNTTFDWAFLSKKECSKYG
Sbjct: 619 VGYNTLFSCTCVPPDPANISISNDTTLAPEYLPTMSSTDMYHNTTFDWAFLSKKECSKYG 678
Query: 635 GNLVGNNCNFVPDITLMSFILFLGTYTSSMALKKFKTSPYFPTTARKLISDFAIILSILI 694
GNLVGNNCNFVPDITLMSFILFLGTYTSSMALKKFKTSPYFPTTARKLISDFAIILSILI
Sbjct: 679 GNLVGNNCNFVPDITLMSFILFLGTYTSSMALKKFKTSPYFPTTARKLISDFAIILSILI 738
Query: 695 FCVIDALVGVDTPKLIVPSEFKPTSPNRGWFVPPFGENPWWVCLAAAIPALLVTILIFMD 754
FCVIDALVGVDTPKLIVPSEFKPTSPNRGWFVPPFGENPWWVCLAAAIPALLVTILIFMD
Sbjct: 739 FCVIDALVGVDTPKLIVPSEFKPTSPNRGWFVPPFGENPWWVCLAAAIPALLVTILIFMD 798
Query: 755 QQITAVIVNRKEHKLKKGAGYHLDLFWVAILMVICSLMALPWYVAATVISIAHIDSLKME 814
QQITAVIVNRKEHKLKKGAGYHLDLFWVAILMVICSLMALPWYVAATVISIAHIDSLKME
Sbjct: 799 QQITAVIVNRKEHKLKKGAGYHLDLFWVAILMVICSLMALPWYVAATVISIAHIDSLKME 858
Query: 815 TETSAPGEQPKFLGVREQRVTGTLVFILTGLSVFMAPILKFIPMPVLYGVFLYMGVASLN 874
TETSAPGEQPKFLGVREQRVTGTLVFILTGLSVFMAPILKFIPMPVLYGVFLYMGVASLN
Sbjct: 859 TETSAPGEQPKFLGVREQRVTGTLVFILTGLSVFMAPILKFIPMPVLYGVFLYMGVASLN 918
Query: 875 GVQFMDRLKLLLMPLKHQPDFIYLRHVPLRRVHLFTFLQVLCLALLWILKSTVAAIIFPV 934
GVQFMDRLKLLLMPLKHQPDFIYLRHVPLRRVHLFTFLQVLCLALLWILKSTVAAIIFPV
Sbjct: 919 GVQFMDRLKLLLMPLKHQPDFIYLRHVPLRRVHLFTFLQVLCLALLWILKSTVAAIIFPV 978
Query: 935 MILALVAVRKGMDYLFSQHDLSFLDDVIPEKDKKKKEDEKKKKKKKGSLDSDNDD 989
MILALVAVRKGMDYLFSQHDLSFLDDVIPEKDKKKKEDEKKKKKKKGSLDSDNDD
Sbjct: 979 MILALVAVRKGMDYLFSQHDLSFLDDVIPEKDKKKKEDEKKKKKKKGSLDSDNDD 1033
>gi|19743827 sodium bicarbonate transporter 4 isoform c [Homo sapiens]
Length = 1121
Score = 1306 bits (3381), Expect = 0.0
Identities = 659/1021 (64%), Positives = 799/1021 (78%), Gaps = 60/1021 (5%)
Query: 42 SPAAERIRFILGEEDDSPAPPQLFTELDELLAVDGQEMEWKETARWIKFEEKVEQGGERW 101
SPAAE+++ ILGEED++P P LFTE+D L DG +MEWKE+ARWIKFEEKVE+GGERW
Sbjct: 92 SPAAEQLQDILGEEDEAPNPT-LFTEMDTLQH-DGDQMEWKESARWIKFEEKVEEGGERW 149
Query: 102 SKPHVATLSLHSLFELRTCMEKGSIMLDREASSLPQLVEMIVDHQIETGLLKPELKDKVT 161
SKPHV+TLSLHSLFELRTC++ G+++LD ++ SLPQ+++ +++ QIE GLL+PEL+++V+
Sbjct: 150 SKPHVSTLSLHSLFELRTCLQTGTVLLDLDSGSLPQIIDDVIEKQIEDGLLRPELRERVS 209
Query: 162 YTLLRKHRHQTKKSNLRSLADIGKTVSSASRMFTNPDNGSPAMTHR-------------- 207
Y LLR+HRHQTKK RSLADIGK+VS+ +R P++ H
Sbjct: 210 YVLLRRHRHQTKKPIHRSLADIGKSVSTTNRSPARSPGAGPSLHHSTEDLRMRQSANYGR 269
Query: 208 --NLTSSSLNDISDKPEKDQLKNKFMKKLPRDAEASNVLVGEVDFLDTPFIAFVRLQQAV 265
+ S S+NDIS P DQ KNKFMKK+P+D+EASNVLVGEVDFLD PFIAFVRL Q+
Sbjct: 270 LCHAQSRSMNDISLTPNTDQRKNKFMKKIPKDSEASNVLVGEVDFLDQPFIAFVRLIQSA 329
Query: 266 MLGALTEVPVPTRFLFILLGPKGKAKSYHEIGRAIATLMSDEVFHDIAYKAKDRHDLIAG 325
MLG +TEVPVPTRFLFILLGP G+AKSY+EIGRAIATLM D++F D+AYKA++R DLIAG
Sbjct: 330 MLGGVTEVPVPTRFLFILLGPSGRAKSYNEIGRAIATLMVDDLFSDVAYKARNREDLIAG 389
Query: 326 IDEFLDEVIVLPPGEWDPAIRIEPPKSLPSSDKRKNMYSGGENVQMNGDTPHDGGHGGGG 385
IDEFLDEVIVLPPGEWDP IRIEPPK +PS+DKRK+++S E QMNG GG GGG
Sbjct: 390 IDEFLDEVIVLPPGEWDPNIRIEPPKKVPSADKRKSVFSLAELGQMNGSVGGGGGAPGGG 449
Query: 386 HGDC--------------------------------EELQRTGRFCGGLIKDIKRKAPFF 413
+G EEL TGRF GGL DIKRK P+F
Sbjct: 450 NGGGGGGGSGGGAGSGGAGGTSSGDDGEMPAMHEIGEELIWTGRFFGGLCLDIKRKLPWF 509
Query: 414 ASDFYDALNIQALSAILFIYLATVTNAITFGGLLGDATDNMQGVLESFLGTAVSGAIFCL 473
SDFYD +IQ++SAILFIYL +TNAITFGGLLGDATDN QGV+ESFLGTA++G++FCL
Sbjct: 510 PSDFYDGFHIQSISAILFIYLGCITNAITFGGLLGDATDNYQGVMESFLGTAMAGSLFCL 569
Query: 474 FAGQPLTILSSTGPVLVFERLLFNFSKDNNFDYLEFRLWIGLWSAFLCLILVATDASFLV 533
F+GQPL ILSSTGP+L+FE+LLF+FSK N DY+EFRLWIGL SA CLILVATDASF++
Sbjct: 570 FSGQPLIILSSTGPILIFEKLLFDFSKGNGLDYMEFRLWIGLHSAVQCLILVATDASFII 629
Query: 534 QYFTRFTEEGFSSLISFIFIYDAFKKMIKLADYYPINSNFKVGYNTLFSCTCVPPDPANI 593
+Y TRFTEEGFS+LISFIFIYDA KKMI YYPIN +FK + T + C CV PD N
Sbjct: 630 KYITRFTEEGFSTLISFIFIYDAIKKMIGAFKYYPINMDFKPNFITTYKCECVAPDTVNT 689
Query: 594 SISNDTT-LAPEYLPTMSSTDMYHNTTFDWAFLSKKECSKYGGNLVGNNCNFVPDITLMS 652
++ N + LAP+ S ++ + T DW+ LSKKEC YGG L+GN+C F+PD+ LMS
Sbjct: 690 TVFNASAPLAPD--TNASLYNLLNLTALDWSLLSKKECLSYGGRLLGNSCKFIPDLALMS 747
Query: 653 FILFLGTYTSSMALKKFKTSPYFPTTARKLISDFAIILSILIFCVIDALVGVDTPKLIVP 712
FILF GTY+ ++ LKKFK S YFPT R L++DF+I+ SIL+FC IDA G++TPKL VP
Sbjct: 748 FILFFGTYSMTLTLKKFKFSRYFPTKVRALVADFSIVFSILMFCGIDACFGLETPKLHVP 807
Query: 713 SEFKPTSPNRGWFVPPFGENPWWVCLAAAIPALLVTILIFMDQQITAVIVNRKEHKLKKG 772
S KPT P+RGWFV PFG+NPWWV A+ +PALLVTILIFMDQQITAVIVNRKE+KLKK
Sbjct: 808 SVIKPTRPDRGWFVAPFGKNPWWVYPASILPALLVTILIFMDQQITAVIVNRKENKLKKA 867
Query: 773 AGYHLDLFWVAILMVICSLMALPWYVAATVISIAHIDSLKMETETSAPGEQPKFLGVREQ 832
AGYHLDLFWV ILM +CS M LPWYVAATVISIAHIDSLKMETETSAPGEQP+FLGVREQ
Sbjct: 868 AGYHLDLFWVGILMALCSFMGLPWYVAATVISIAHIDSLKMETETSAPGEQPQFLGVREQ 927
Query: 833 RVTGTLVFILTGLSVFMAPILKFIPMPVLYGVFLYMGVASLNGVQFMDRLKLLLMPLKHQ 892
RVTG +VFILTG+SVF+APILK IP+PVLYGVFLYMGVASLNG+QF +R KL LMP KHQ
Sbjct: 928 RVTGIIVFILTGISVFLAPILKCIPLPVLYGVFLYMGVASLNGIQFWERCKLFLMPAKHQ 987
Query: 893 PDFIYLRHVPLRRVHLFTFLQVLCLALLWILKSTVAAIIFPVMILALVAVRKGMDYLFSQ 952
PD +LRHVPLRR+HLFT +Q+LCLA+LWILKSTVAAIIFPVMIL L+ VR+ +D++FSQ
Sbjct: 988 PDHAFLRHVPLRRIHLFTLVQILCLAVLWILKSTVAAIIFPVMILGLIIVRRLLDFIFSQ 1047
Query: 953 HDLSFLDDVIPEKDKKKKEDEKKKKKKKGSLDSDNDDSDCPYSEKVPS-IKIPMDIMEQQ 1011
HDL+++D+++PEK+ KKE +KK+K+KKG+ + +++ P PS IKIPM+ ++
Sbjct: 1048 HDLAWIDNILPEKE--KKETDKKRKRKKGAHEDCDEEPQFP----PPSVIKIPMESVQSD 1101
Query: 1012 P 1012
P
Sbjct: 1102 P 1102
>gi|125987596 sodium bicarbonate transporter 4 isoform a [Homo
sapiens]
Length = 1137
Score = 1296 bits (3354), Expect = 0.0
Identities = 659/1037 (63%), Positives = 799/1037 (77%), Gaps = 76/1037 (7%)
Query: 42 SPAAERIRFILGEEDDSPAPPQLFTELDELLAVDGQEMEWKETARWIKFEEKVEQGGERW 101
SPAAE+++ ILGEED++P P LFTE+D L DG +MEWKE+ARWIKFEEKVE+GGERW
Sbjct: 92 SPAAEQLQDILGEEDEAPNPT-LFTEMDTLQH-DGDQMEWKESARWIKFEEKVEEGGERW 149
Query: 102 SKPHVATLSLHSLFELRTCMEKGSIMLDREASSLPQLVEMIVDHQIETGLLKPELKDKVT 161
SKPHV+TLSLHSLFELRTC++ G+++LD ++ SLPQ+++ +++ QIE GLL+PEL+++V+
Sbjct: 150 SKPHVSTLSLHSLFELRTCLQTGTVLLDLDSGSLPQIIDDVIEKQIEDGLLRPELRERVS 209
Query: 162 YTLLRKHRHQTKKSNLRSLADIGKTVSSASRMFTNPDNGSPAMTHR-------------- 207
Y LLR+HRHQTKK RSLADIGK+VS+ +R P++ H
Sbjct: 210 YVLLRRHRHQTKKPIHRSLADIGKSVSTTNRSPARSPGAGPSLHHSTEDLRMRQSANYGR 269
Query: 208 --NLTSSSLNDISDKPEKDQLKNKFMKKLPRDAEASNVLVGEVDFLDTPFIAFVRLQQAV 265
+ S S+NDIS P DQ KNKFMKK+P+D+EASNVLVGEVDFLD PFIAFVRL Q+
Sbjct: 270 LCHAQSRSMNDISLTPNTDQRKNKFMKKIPKDSEASNVLVGEVDFLDQPFIAFVRLIQSA 329
Query: 266 MLGALTEVPVPTRFLFILLGPKGKAKSYHEIGRAIATLMSDEVFHDIAYKAKDRHDLIAG 325
MLG +TEVPVPTRFLFILLGP G+AKSY+EIGRAIATLM D++F D+AYKA++R DLIAG
Sbjct: 330 MLGGVTEVPVPTRFLFILLGPSGRAKSYNEIGRAIATLMVDDLFSDVAYKARNREDLIAG 389
Query: 326 IDEFLDEVIVLPPGEWDPAIRIEPPKSLPSSDKRKNMYSGGENVQMNGDTPHDGGHGGGG 385
IDEFLDEVIVLPPGEWDP IRIEPPK +PS+DKRK+++S E QMNG GG GGG
Sbjct: 390 IDEFLDEVIVLPPGEWDPNIRIEPPKKVPSADKRKSVFSLAELGQMNGSVGGGGGAPGGG 449
Query: 386 HGDC--------------------------------EELQRTGRFCGGLIKDIKRKAPFF 413
+G EEL TGRF GGL DIKRK P+F
Sbjct: 450 NGGGGGGGSGGGAGSGGAGGTSSGDDGEMPAMHEIGEELIWTGRFFGGLCLDIKRKLPWF 509
Query: 414 ASDFYDALNIQALSAILFIYLATVTNAITFGGLLGDATDNMQGVLESFLGTAVSGAIFCL 473
SDFYD +IQ++SAILFIYL +TNAITFGGLLGDATDN QGV+ESFLGTA++G++FCL
Sbjct: 510 PSDFYDGFHIQSISAILFIYLGCITNAITFGGLLGDATDNYQGVMESFLGTAMAGSLFCL 569
Query: 474 FAGQPLTILSSTGPVLVFERLLFNFSKDNNFDYLEFRLWIGLWSAFLCLILVATDASFLV 533
F+GQPL ILSSTGP+L+FE+LLF+FSK N DY+EFRLWIGL SA CLILVATDASF++
Sbjct: 570 FSGQPLIILSSTGPILIFEKLLFDFSKGNGLDYMEFRLWIGLHSAVQCLILVATDASFII 629
Query: 534 QYFTRFTEEGFSSLISFIFIYDAFKKMIKLADYYPINSNFKVGYNTLFSCTCVPPDPANI 593
+Y TRFTEEGFS+LISFIFIYDA KKMI YYPIN +FK + T + C CV PD N
Sbjct: 630 KYITRFTEEGFSTLISFIFIYDAIKKMIGAFKYYPINMDFKPNFITTYKCECVAPDTVNT 689
Query: 594 SISNDTT-LAPEYLPTMSSTDMYHNTTFDWAFLSKKECSKYGGNLVGNNCNFVPDITLMS 652
++ N + LAP+ S ++ + T DW+ LSKKEC YGG L+GN+C F+PD+ LMS
Sbjct: 690 TVFNASAPLAPD--TNASLYNLLNLTALDWSLLSKKECLSYGGRLLGNSCKFIPDLALMS 747
Query: 653 FILFLGTYTSSMALKKFKTSPYFPTTARKLISDFAIILSILIFCVIDALVGVDTPKLIVP 712
FILF GTY+ ++ LKKFK S YFPT R L++DF+I+ SIL+FC IDA G++TPKL VP
Sbjct: 748 FILFFGTYSMTLTLKKFKFSRYFPTKVRALVADFSIVFSILMFCGIDACFGLETPKLHVP 807
Query: 713 SEFKPTSPNRGWFVPPFGENPWWVCLAAAIPALLVTILIFMDQQITAVIVNRKEHKLKKG 772
S KPT P+RGWFV PFG+NPWWV A+ +PALLVTILIFMDQQITAVIVNRKE+KLKK
Sbjct: 808 SVIKPTRPDRGWFVAPFGKNPWWVYPASILPALLVTILIFMDQQITAVIVNRKENKLKKA 867
Query: 773 AGYHLDLFWVAILMVICSLMALPWYVAATVISIAHIDSLKMETETSAPGEQPKFLGVREQ 832
AGYHLDLFWV ILM +CS M LPWYVAATVISIAHIDSLKMETETSAPGEQP+FLGVREQ
Sbjct: 868 AGYHLDLFWVGILMALCSFMGLPWYVAATVISIAHIDSLKMETETSAPGEQPQFLGVREQ 927
Query: 833 RVTGTLVFILTGLSVFMAPILKFIPMPVLYGVFLYMGVASLNGVQ--------------- 877
RVTG +VFILTG+SVF+APILK IP+PVLYGVFLYMGVASLNG+Q
Sbjct: 928 RVTGIIVFILTGISVFLAPILKCIPLPVLYGVFLYMGVASLNGIQMGTGGSEFKIQKKLT 987
Query: 878 -FMDRLKLLLMPLKHQPDFIYLRHVPLRRVHLFTFLQVLCLALLWILKSTVAAIIFPVMI 936
F +R KL LMP KHQPD +LRHVPLRR+HLFT +Q+LCLA+LWILKSTVAAIIFPVMI
Sbjct: 988 PFWERCKLFLMPAKHQPDHAFLRHVPLRRIHLFTLVQILCLAVLWILKSTVAAIIFPVMI 1047
Query: 937 LALVAVRKGMDYLFSQHDLSFLDDVIPEKDKKKKEDEKKKKKKKGSLDSDNDDSDCPYSE 996
L L+ VR+ +D++FSQHDL+++D+++PEK+ KKE +KK+K+KKG+ + +++ P
Sbjct: 1048 LGLIIVRRLLDFIFSQHDLAWIDNILPEKE--KKETDKKRKRKKGAHEDCDEEPQFP--- 1102
Query: 997 KVPS-IKIPMDIMEQQP 1012
PS IKIPM+ ++ P
Sbjct: 1103 -PPSVIKIPMESVQSDP 1118
>gi|90403614 solute carrier family 4, sodium bicarbonate
cotransporter, member 8 isoform a [Homo sapiens]
Length = 1093
Score = 1050 bits (2716), Expect = 0.0
Identities = 535/949 (56%), Positives = 687/949 (72%), Gaps = 31/949 (3%)
Query: 45 AERIRFILG-EEDDSPAPPQLFTELDELLAVDGQEMEWKETARWIKFEEKVEQGGERWSK 103
++R++FILG EED+ P +LFTELDE+ +G++ EWKETARW+KFEE VE GGERWSK
Sbjct: 96 SQRVQFILGTEEDEEHVPHELFTELDEICMKEGEDAEWKETARWLKFEEDVEDGGERWSK 155
Query: 104 PHVATLSLHSLFELRTCMEKGSIMLDREASSLPQLVEMIVDHQIETGLLKPELKDKVTYT 163
P+VATLSLHSLFELR+C+ G+++LD A+S+ ++ ++I+D Q + L ++ KV
Sbjct: 156 PYVATLSLHSLFELRSCLINGTVLLDMHANSIEEISDLILDQQELSSDLNDSMRVKVREA 215
Query: 164 LLRKHRHQTKKSN------LRSLADIGKTVSSASRMFTNPDNGSP-AMTHRNL-TSSSLN 215
LL+KH HQ +K +RS A++GK S M + SP ++ NL + +N
Sbjct: 216 LLKKHHHQNEKKRNNLIPIVRSFAEVGKKQSDPHLMDKHGQTVSPQSVPTTNLEVKNGVN 275
Query: 216 DISDKPEKDQLKNKFMKKLPRDAEASNVLVGEVDFLDTPFIAFVRLQQAVMLGALTEVPV 275
+ ++ FMKK+P AEASNVLVGEVD LD P +AFVRL AV+L LTEVP+
Sbjct: 276 CEHSPVDLSKVDLHFMKKIPTGAEASNVLVGEVDILDRPIVAFVRLSPAVLLSGLTEVPI 335
Query: 276 PTRFLFILLGPKGKAKSYHEIGRAIATLMSDEVFHDIAYKAKDRHDLIAGIDEFLDEVIV 335
PTRFLFILLGP GK + YHEIGR++AT+M+DE+FHD+AYKAK+R DL+AGIDEFLD+V V
Sbjct: 336 PTRFLFILLGPVGKGQQYHEIGRSMATIMTDEIFHDVAYKAKERDDLLAGIDEFLDQVTV 395
Query: 336 LPPGEWDPAIRIEPPKSLPSSDKRKNMYSGGENVQMNGDTPHDGGHGGGGHGDCEELQRT 395
LPPGEWDP+IRIEPPK++PS +KRK NV PH GGH G ELQRT
Sbjct: 396 LPPGEWDPSIRIEPPKNVPSQEKRKMPGVPNGNVCHIEQEPH-GGHSG------PELQRT 448
Query: 396 GRFCGGLIKDIKRKAPFFASDFYDALNIQALSAILFIYLATVTNAITFGGLLGDATDNMQ 455
GR GGL+ DIKRKAP++ SD+ DAL++Q L++ LF+Y A ++ ITFGGLLG+AT+
Sbjct: 449 GRLFGGLVLDIKRKAPWYWSDYRDALSLQCLASFLFLYCACMSPVITFGGLLGEATEGRI 508
Query: 456 GVLESFLGTAVSGAIFCLFAGQPLTILSSTGPVLVFERLLFNFSKDNNFDYLEFRLWIGL 515
+ES G +++G + LFAGQ LTIL STGPVLVFE++LF F KD YL R IGL
Sbjct: 509 SAIESLFGASMTGIAYSLFAGQALTILGSTGPVLVFEKILFKFCKDYALSYLSLRACIGL 568
Query: 516 WSAFLCLILVATDASFLVQYFTRFTEEGFSSLISFIFIYDAFKKMIKLADYYPINSNFKV 575
W+AFLC++LVATDAS LV Y TRFTEE F+SLI IFIY+A +K+I LA+ YPI+ + ++
Sbjct: 569 WTAFLCIVLVATDASSLVCYITRFTEEAFASLICIIFIYEAIEKLIHLAETYPIHMHSQL 628
Query: 576 GYNTLFSCTCVPPDPANISISNDTTLAPEYLPTMSSTDMYHNTTFDWAFLSKKECSKYGG 635
+ +L+ C C P+ N + TL + + +++ WA L+ EC + G
Sbjct: 629 DHLSLYYCRCTLPENPN-----NHTLQYWKDHNIVTAEVH------WANLTVSECQEMHG 677
Query: 636 NLVGNNCN----FVPDITLMSFILFLGTYTSSMALKKFKTSPYFPTTARKLISDFAIILS 691
+G+ C + PD+ S ILF T+ S LK FKTS YFPT R ++SDFA+ L+
Sbjct: 678 EFMGSACGHHGPYTPDVLFWSCILFFTTFILSSTLKTFKTSRYFPTRVRSMVSDFAVFLT 737
Query: 692 ILIFCVIDALVGVDTPKLIVPSEFKPTSPNRGWFVPPFGENPWWVCLAAAIPALLVTILI 751
I +ID L+GV +PKL VPS FKPT +RGW + P G NPWW +AA IPALL TILI
Sbjct: 738 IFTMVIIDFLIGVPSPKLQVPSVFKPTRDDRGWIINPIGPNPWWTVIAAIIPALLCTILI 797
Query: 752 FMDQQITAVIVNRKEHKLKKGAGYHLDLFWVAILMVICSLMALPWYVAATVISIAHIDSL 811
FMDQQITAVI+NRKEHKLKKG GYHLDL VAI++ +CS+M LPW+VAATV+SI H++SL
Sbjct: 798 FMDQQITAVIINRKEHKLKKGCGYHLDLLMVAIMLGVCSIMGLPWFVAATVLSITHVNSL 857
Query: 812 KMETETSAPGEQPKFLGVREQRVTGTLVFILTGLSVFMAPILKFIPMPVLYGVFLYMGVA 871
K+E+E SAPGEQPKFLG+REQRVTG ++F+L G SVFM ILKFIPMPVLYGVFLYMGV+
Sbjct: 858 KLESECSAPGEQPKFLGIREQRVTGLMIFVLMGCSVFMTAILKFIPMPVLYGVFLYMGVS 917
Query: 872 SLNGVQFMDRLKLLLMPLKHQPDFIYLRHVPLRRVHLFTFLQVLCLALLWILKSTVAAII 931
SL G+QF DRLKL MP KHQPDFIYLRHVPLR+VHLFT +Q+ CL LLW++K++ AAI+
Sbjct: 918 SLQGIQFFDRLKLFGMPAKHQPDFIYLRHVPLRKVHLFTLIQLTCLVLLWVIKASPAAIV 977
Query: 932 FPVMILALVAVRKGMDYLFSQHDLSFLDDVIPEKDKKKKEDEKKKKKKK 980
FP+M+LALV VRK MD FS+ +LS+LDD++PE KKK +D KKK K++
Sbjct: 978 FPMMVLALVFVRKVMDLCFSKRELSWLDDLMPESKKKKLDDAKKKAKEE 1026
>gi|90568034 solute carrier family 4, sodium bicarbonate
cotransporter, member 8 isoform b [Homo sapiens]
Length = 1044
Score = 1050 bits (2716), Expect = 0.0
Identities = 535/949 (56%), Positives = 687/949 (72%), Gaps = 31/949 (3%)
Query: 45 AERIRFILG-EEDDSPAPPQLFTELDELLAVDGQEMEWKETARWIKFEEKVEQGGERWSK 103
++R++FILG EED+ P +LFTELDE+ +G++ EWKETARW+KFEE VE GGERWSK
Sbjct: 96 SQRVQFILGTEEDEEHVPHELFTELDEICMKEGEDAEWKETARWLKFEEDVEDGGERWSK 155
Query: 104 PHVATLSLHSLFELRTCMEKGSIMLDREASSLPQLVEMIVDHQIETGLLKPELKDKVTYT 163
P+VATLSLHSLFELR+C+ G+++LD A+S+ ++ ++I+D Q + L ++ KV
Sbjct: 156 PYVATLSLHSLFELRSCLINGTVLLDMHANSIEEISDLILDQQELSSDLNDSMRVKVREA 215
Query: 164 LLRKHRHQTKKSN------LRSLADIGKTVSSASRMFTNPDNGSP-AMTHRNL-TSSSLN 215
LL+KH HQ +K +RS A++GK S M + SP ++ NL + +N
Sbjct: 216 LLKKHHHQNEKKRNNLIPIVRSFAEVGKKQSDPHLMDKHGQTVSPQSVPTTNLEVKNGVN 275
Query: 216 DISDKPEKDQLKNKFMKKLPRDAEASNVLVGEVDFLDTPFIAFVRLQQAVMLGALTEVPV 275
+ ++ FMKK+P AEASNVLVGEVD LD P +AFVRL AV+L LTEVP+
Sbjct: 276 CEHSPVDLSKVDLHFMKKIPTGAEASNVLVGEVDILDRPIVAFVRLSPAVLLSGLTEVPI 335
Query: 276 PTRFLFILLGPKGKAKSYHEIGRAIATLMSDEVFHDIAYKAKDRHDLIAGIDEFLDEVIV 335
PTRFLFILLGP GK + YHEIGR++AT+M+DE+FHD+AYKAK+R DL+AGIDEFLD+V V
Sbjct: 336 PTRFLFILLGPVGKGQQYHEIGRSMATIMTDEIFHDVAYKAKERDDLLAGIDEFLDQVTV 395
Query: 336 LPPGEWDPAIRIEPPKSLPSSDKRKNMYSGGENVQMNGDTPHDGGHGGGGHGDCEELQRT 395
LPPGEWDP+IRIEPPK++PS +KRK NV PH GGH G ELQRT
Sbjct: 396 LPPGEWDPSIRIEPPKNVPSQEKRKMPGVPNGNVCHIEQEPH-GGHSG------PELQRT 448
Query: 396 GRFCGGLIKDIKRKAPFFASDFYDALNIQALSAILFIYLATVTNAITFGGLLGDATDNMQ 455
GR GGL+ DIKRKAP++ SD+ DAL++Q L++ LF+Y A ++ ITFGGLLG+AT+
Sbjct: 449 GRLFGGLVLDIKRKAPWYWSDYRDALSLQCLASFLFLYCACMSPVITFGGLLGEATEGRI 508
Query: 456 GVLESFLGTAVSGAIFCLFAGQPLTILSSTGPVLVFERLLFNFSKDNNFDYLEFRLWIGL 515
+ES G +++G + LFAGQ LTIL STGPVLVFE++LF F KD YL R IGL
Sbjct: 509 SAIESLFGASMTGIAYSLFAGQALTILGSTGPVLVFEKILFKFCKDYALSYLSLRACIGL 568
Query: 516 WSAFLCLILVATDASFLVQYFTRFTEEGFSSLISFIFIYDAFKKMIKLADYYPINSNFKV 575
W+AFLC++LVATDAS LV Y TRFTEE F+SLI IFIY+A +K+I LA+ YPI+ + ++
Sbjct: 569 WTAFLCIVLVATDASSLVCYITRFTEEAFASLICIIFIYEAIEKLIHLAETYPIHMHSQL 628
Query: 576 GYNTLFSCTCVPPDPANISISNDTTLAPEYLPTMSSTDMYHNTTFDWAFLSKKECSKYGG 635
+ +L+ C C P+ N + TL + + +++ WA L+ EC + G
Sbjct: 629 DHLSLYYCRCTLPENPN-----NHTLQYWKDHNIVTAEVH------WANLTVSECQEMHG 677
Query: 636 NLVGNNCN----FVPDITLMSFILFLGTYTSSMALKKFKTSPYFPTTARKLISDFAIILS 691
+G+ C + PD+ S ILF T+ S LK FKTS YFPT R ++SDFA+ L+
Sbjct: 678 EFMGSACGHHGPYTPDVLFWSCILFFTTFILSSTLKTFKTSRYFPTRVRSMVSDFAVFLT 737
Query: 692 ILIFCVIDALVGVDTPKLIVPSEFKPTSPNRGWFVPPFGENPWWVCLAAAIPALLVTILI 751
I +ID L+GV +PKL VPS FKPT +RGW + P G NPWW +AA IPALL TILI
Sbjct: 738 IFTMVIIDFLIGVPSPKLQVPSVFKPTRDDRGWIINPIGPNPWWTVIAAIIPALLCTILI 797
Query: 752 FMDQQITAVIVNRKEHKLKKGAGYHLDLFWVAILMVICSLMALPWYVAATVISIAHIDSL 811
FMDQQITAVI+NRKEHKLKKG GYHLDL VAI++ +CS+M LPW+VAATV+SI H++SL
Sbjct: 798 FMDQQITAVIINRKEHKLKKGCGYHLDLLMVAIMLGVCSIMGLPWFVAATVLSITHVNSL 857
Query: 812 KMETETSAPGEQPKFLGVREQRVTGTLVFILTGLSVFMAPILKFIPMPVLYGVFLYMGVA 871
K+E+E SAPGEQPKFLG+REQRVTG ++F+L G SVFM ILKFIPMPVLYGVFLYMGV+
Sbjct: 858 KLESECSAPGEQPKFLGIREQRVTGLMIFVLMGCSVFMTAILKFIPMPVLYGVFLYMGVS 917
Query: 872 SLNGVQFMDRLKLLLMPLKHQPDFIYLRHVPLRRVHLFTFLQVLCLALLWILKSTVAAII 931
SL G+QF DRLKL MP KHQPDFIYLRHVPLR+VHLFT +Q+ CL LLW++K++ AAI+
Sbjct: 918 SLQGIQFFDRLKLFGMPAKHQPDFIYLRHVPLRKVHLFTLIQLTCLVLLWVIKASPAAIV 977
Query: 932 FPVMILALVAVRKGMDYLFSQHDLSFLDDVIPEKDKKKKEDEKKKKKKK 980
FP+M+LALV VRK MD FS+ +LS+LDD++PE KKK +D KKK K++
Sbjct: 978 FPMMVLALVFVRKVMDLCFSKRELSWLDDLMPESKKKKLDDAKKKAKEE 1026
>gi|155722998 solute carrier family 4, sodium bicarbonate
transporter-like, member 10 [Homo sapiens]
Length = 1088
Score = 1050 bits (2714), Expect = 0.0
Identities = 537/953 (56%), Positives = 684/953 (71%), Gaps = 40/953 (4%)
Query: 45 AERIRFILGEEDDSPA--PPQLFTELDELLAVDGQEMEWKETARWIKFEEKVEQGGERWS 102
++R++FILG EDD P LFTELDE+ +G++ EW+ETARW+KFEE VE GGERWS
Sbjct: 96 SQRVQFILGTEDDDEEHIPHDLFTELDEICWREGEDAEWRETARWLKFEEDVEDGGERWS 155
Query: 103 KPHVATLSLHSLFELRTCMEKGSIMLDREASSLPQLVEMIVDHQIETGLLKPELKDKVTY 162
KP+VATLSLHSLFELR+C+ G+++LD A++L ++ +M++D Q+ +G L +++ +V
Sbjct: 156 KPYVATLSLHSLFELRSCILNGTVLLDMHANTLEEIADMVLDQQVSSGQLNEDVRHRVHE 215
Query: 163 TLLRKHRHQTKKSN------LRSLADIGKTVSSASRMFTNPDN-----GSPAMTHRNLTS 211
L+++H HQ +K +RS ADIGK S + M N +PA
Sbjct: 216 ALMKQHHHQNQKKLTNRIPIVRSFADIGKKQSEPNSMDKNAGQVVSPQSAPACVENKNDV 275
Query: 212 SSLNDISDKPEKDQLKNKFMKKLPRDAEASNVLVGEVDFLDTPFIAFVRLQQAVMLGALT 271
S N D + D FMKK+P AEASN+LVGE++FLD +AFVRL AV+L L
Sbjct: 276 SRENSTVDFSKVDL---HFMKKIPPGAEASNILVGELEFLDRTVVAFVRLSPAVLLQGLA 332
Query: 272 EVPVPTRFLFILLGPKGKAKSYHEIGRAIATLMSDEVFHDIAYKAKDRHDLIAGIDEFLD 331
EVP+PTRFLFILLGP GK + YHEIGR+IATLM+DEVFHD+AYKAKDR+DL++GIDEFLD
Sbjct: 333 EVPIPTRFLFILLGPLGKGQQYHEIGRSIATLMTDEVFHDVAYKAKDRNDLVSGIDEFLD 392
Query: 332 EVIVLPPGEWDPAIRIEPPKSLPSSDKRKNMYSGGENVQMNGDTPHDGGHGGGGHGDCEE 391
+V VLPPGEWDP+IRIEPPK++PS +KRK + + +G+ GGH G E
Sbjct: 393 QVTVLPPGEWDPSIRIEPPKNVPSQEKRK-IPAVPNGTAAHGEAEPHGGHSG------PE 445
Query: 392 LQRTGRFCGGLIKDIKRKAPFFASDFYDALNIQALSAILFIYLATVTNAITFGGLLGDAT 451
LQRTGR GGLI DIKRKAP+F SDF DA ++Q L++ LF+Y A ++ ITFGGLLG+AT
Sbjct: 446 LQRTGRIFGGLILDIKRKAPYFWSDFRDAFSLQCLASFLFLYCACMSPVITFGGLLGEAT 505
Query: 452 DNMQGVLESFLGTAVSGAIFCLFAGQPLTILSSTGPVLVFERLLFNFSKDNNFDYLEFRL 511
+ +ES G +++G + LF GQPLTIL STGPVLVFE++LF F K+ YL R
Sbjct: 506 EGRISAIESLFGASMTGIAYSLFGGQPLTILGSTGPVLVFEKILFKFCKEYGLSYLSLRA 565
Query: 512 WIGLWSAFLCLILVATDASFLVQYFTRFTEEGFSSLISFIFIYDAFKKMIKLADYYPINS 571
IGLW+A LC+ILVATDAS LV Y TRFTEE F+SLI IFIY+A +K+ +L++ YPIN
Sbjct: 566 SIGLWTATLCIILVATDASSLVCYITRFTEEAFASLICIIFIYEALEKLFELSEAYPINM 625
Query: 572 NFKVGYNTLFSCTCVPP-DPANISISNDTTLAPEYLPTMSSTDMYHNTTFDWAFLSKKEC 630
+ + T +SC CV P +P+N TL +S++D+ W L+ EC
Sbjct: 626 HNDLELLTQYSCNCVEPHNPSN------GTLKEWRESNISASDII------WENLTVSEC 673
Query: 631 SKYGGNLVGNNCN----FVPDITLMSFILFLGTYTSSMALKKFKTSPYFPTTARKLISDF 686
G VG C +VPD+ S ILF T T S LK+FKTS YFPT R ++SDF
Sbjct: 674 KSLHGEYVGRACGHDHPYVPDVLFWSVILFFSTVTLSATLKQFKTSRYFPTKVRSIVSDF 733
Query: 687 AIILSILIFCVIDALVGVDTPKLIVPSEFKPTSPNRGWFVPPFGENPWWVCLAAAIPALL 746
A+ L+IL +ID +G+ +PKL VPS FKPT +RGWFV P G NPWW +AA IPALL
Sbjct: 734 AVFLTILCMVLIDYAIGIPSPKLQVPSVFKPTRDDRGWFVTPLGPNPWWTVIAAIIPALL 793
Query: 747 VTILIFMDQQITAVIVNRKEHKLKKGAGYHLDLFWVAILMVICSLMALPWYVAATVISIA 806
TILIFMDQQITAVI+NRKEHKLKKG GYHLDL VA+++ +CS+M LPW+VAATV+SI
Sbjct: 794 CTILIFMDQQITAVIINRKEHKLKKGCGYHLDLLMVAVMLGVCSIMGLPWFVAATVLSIT 853
Query: 807 HIDSLKMETETSAPGEQPKFLGVREQRVTGTLVFILTGLSVFMAPILKFIPMPVLYGVFL 866
H++SLK+E+E SAPGEQPKFLG+REQRVTG ++FIL G SVFM ILKFIPMPVLYGVFL
Sbjct: 854 HVNSLKLESECSAPGEQPKFLGIREQRVTGLMIFILMGSSVFMTSILKFIPMPVLYGVFL 913
Query: 867 YMGVASLNGVQFMDRLKLLLMPLKHQPDFIYLRHVPLRRVHLFTFLQVLCLALLWILKST 926
YMG +SL G+QF DR+KL MP KHQPDFIYLRHVPLR+VHLFT +Q+ CL LLWI+K +
Sbjct: 914 YMGASSLKGIQFFDRIKLFWMPAKHQPDFIYLRHVPLRKVHLFTIIQMSCLGLLWIIKVS 973
Query: 927 VAAIIFPVMILALVAVRKGMDYLFSQHDLSFLDDVIPEKDKKKKEDEKKKKKK 979
AAI+FP+M+LALV VRK MD LF++ +LS+LDD++PE KKK ED +K++++
Sbjct: 974 RAAIVFPMMVLALVFVRKLMDLLFTKRELSWLDDLMPESKKKKLEDAEKEEEQ 1026
>gi|151101449 solute carrier family 4, sodium bicarbonate
cotransporter, member 9 [Homo sapiens]
Length = 959
Score = 942 bits (2436), Expect = 0.0
Identities = 504/953 (52%), Positives = 656/953 (68%), Gaps = 49/953 (5%)
Query: 59 PAPPQLFTELDELLAVDGQEMEWKETARWIKFEEKVEQGGERWSKPHVATLSLHSLFELR 118
P P LF +L+ELL Q +EW+ET RW+ FEEK+E RWS PHV TL+L SL +LR
Sbjct: 51 PKDPLLFIQLNELLGWP-QALEWRETGRWVLFEEKLEVAAGRWSAPHVPTLALPSLQKLR 109
Query: 119 TCMEKGSIMLDREASSLPQLVEMIVDHQIETGLLKPELKDKVTYTLLRKHRHQTKKSNLR 178
+ + +G ++LD A SL +LVE + ++E+ L PEL+ ++ LL++ +H + +
Sbjct: 110 SLLAEGLVLLDCPAQSLLELVEQVT--RVES--LSPELRGQLQALLLQRPQHYNQTTG-- 163
Query: 179 SLADIGKTVSSASRMFTNPDNGSPAMTHRNLTSSSLNDISDKPEKDQLKNKFMKKLPRDA 238
T P GS TH S D + P ++Q +N +KLP A
Sbjct: 164 ----------------TRPCWGS---THPRKAS----DNEEAPLREQCQNPLRQKLPPGA 200
Query: 239 EASNVLVGEVDFLDTPFIAFVRLQQAVMLGALTEVPVPTRFLFILLGPKGKAKSYHEIGR 298
EA VL GE+ FL P AFVRL+ V+LG+LTEV +P+RF +LLGP K YHE+GR
Sbjct: 201 EAGTVLAGELGFLAQPLGAFVRLRNPVVLGSLTEVSLPSRFFCLLLGPCMLGKGYHEMGR 260
Query: 299 AIATLMSDEVFHDIAYKAKDRHDLIAGIDEFLDEVIVLPPGEWDPAIRIEPPKSLPSSDK 358
A A L+SD F +A + HDL+A +D FL+EV VLPPG WDP RI PPK LPS K
Sbjct: 261 AAAVLLSDPQFQWSVRRASNLHDLLAALDAFLEEVTVLPPGRWDPTARIPPPKCLPSQHK 320
Query: 359 RKNMYSGGENVQMNGD-----TPHDGGHGGGGHGDCEELQRTGRFCGGLIKDIKRKAPFF 413
R + ++ G T + H G H ELQRTGR GGLI+D++RK P++
Sbjct: 321 RLP----SQQREIRGPAVPRLTSAEDRHRHGPHAHSPELQRTGRLFGGLIQDVRRKVPWY 376
Query: 414 ASDFYDALNIQALSAILFIYLATVTNAITFGGLLGDATDNMQGVLESFLGTAVSGAIFCL 473
SDF DAL++Q SA+L+IYLATVTNAITFGGLLGDATD QGVLESFLGTAV+GA FCL
Sbjct: 377 PSDFLDALHLQCFSAVLYIYLATVTNAITFGGLLGDATDGAQGVLESFLGTAVAGAAFCL 436
Query: 474 FAGQPLTILSSTGPVLVFERLLFNFSKDNNFDYLEFRLWIGLWSAFLCLILVATDASFLV 533
AGQPLTILSSTGPVLVFERLLF+FS+D + DYL FRLW+G+W A CL+LVAT+AS LV
Sbjct: 437 MAGQPLTILSSTGPVLVFERLLFSFSRDYSLDYLPFRLWVGIWVATFCLVLVATEASVLV 496
Query: 534 QYFTRFTEEGFSSLISFIFIYDAFKKMIKLADYYPINSNFKVGYNTLFSCTCVPPDPANI 593
+YFTRFTEEGF +LIS IFIYDA KM+ L YPI K G ++ + C C P P
Sbjct: 497 RYFTRFTEEGFCALISLIFIYDAVGKMLNLTHTYPIQ---KPG-SSAYGCLCQYPGPGG- 551
Query: 594 SISNDTTLAPEYLPTMSSTDMYHNTTFDWAFLSKKECSKYGGNLVGNNCNFVPDITLMSF 653
+ S P+ + S D+ + + L EC++ GG+ G C+ VPDI S
Sbjct: 552 NESQWIRTRPKDRDDIVSMDL---GLINASLLPPPECTRQGGHPRGPGCHTVPDIAFFSL 608
Query: 654 ILFLGTYTSSMALKKFKTSPYFPTTARKLISDFAIILSILIFCVIDALVGVDTPKLIVPS 713
+LFL ++ +MALK KTS +FP+ RK +SDF+ +L+IL+ C +DA +G+ TPKL+VP
Sbjct: 609 LLFLTSFFFAMALKCVKTSRFFPSVVRKGLSDFSSVLAILLGCGLDAFLGLATPKLMVPR 668
Query: 714 EFKPTSPNRGWFVPPFGENPWWVCLAAAIPALLVTILIFMDQQITAVIVNRKEHKLKKGA 773
EFKPT P RGW V PFG NPWW +AAA+PALL++ILIFMDQQITAVI+NR E++L+KGA
Sbjct: 669 EFKPTLPGRGWLVSPFGANPWWWSVAAALPALLLSILIFMDQQITAVILNRMEYRLQKGA 728
Query: 774 GYHLDLFWVAILMVICSLMALPWYVAATVISIAHIDSLKMETETSAPGEQPKFLGVREQR 833
G+HLDLF VA+LM++ S + LPWYV+ATVIS+AH+DSL+ E+ APGE+P FLG+REQR
Sbjct: 729 GFHLDLFCVAVLMLLTSALGLPWYVSATVISLAHMDSLRRESRACAPGERPNFLGIREQR 788
Query: 834 VTGTLVFILTGLSVFMAPILKFIPMPVLYGVFLYMGVASLNGVQFMDRLKLLLMPLKHQP 893
+TG +VFILTG S+F+AP+LKFIPMPVLYG+FLYMGVA+L+ +QF +R+KLLLMP KHQP
Sbjct: 789 LTGLVVFILTGASIFLAPVLKFIPMPVLYGIFLYMGVAALSSIQFTNRVKLLLMPAKHQP 848
Query: 894 DFIYLRHVPLRRVHLFTFLQVLCLALLWILKSTVAAIIFPVMILALVAVRKGMDYLFSQH 953
D + LRHVPL RVHLFT +Q+ CL LLWI+KST AAIIFP+M+L LV VRK ++ +FS
Sbjct: 849 DLLLLRHVPLTRVHLFTAIQLACLGLLWIIKSTPAAIIFPLMLLGLVGVRKALERVFSPQ 908
Query: 954 DLSFLDDVIPEKDKKKKEDEKKKKKKKGSLDSDNDDSDCPYSEKVPSIKIPMD 1006
+L +LD+++PE++ + EK + + SD++DS+ Y K P I I ++
Sbjct: 909 ELLWLDELMPEEE--RSIPEKGLEPEHSFSGSDSEDSELMYQPKAPEINISVN 959
>gi|134288865 solute carrier family 4, sodium bicarbonate
cotransporter, member 7 [Homo sapiens]
Length = 1214
Score = 910 bits (2353), Expect = 0.0
Identities = 466/829 (56%), Positives = 592/829 (71%), Gaps = 35/829 (4%)
Query: 201 SPAMTHRNLTSSSLNDISDKPEKDQLKNK----------FMKKLPRDAEASNVLVGEVDF 250
SP NL +S +I +N FM+K+P AEASNVLVGEVDF
Sbjct: 379 SPQSAPGNLDNSKSGEIKGNGSGGSRENSTVDFSKVDMNFMRKIPTGAEASNVLVGEVDF 438
Query: 251 LDTPFIAFVRLQQAVMLGALTEVPVPTRFLFILLGPKGKAKSYHEIGRAIATLMSDEVFH 310
L+ P IAFVRL AV+L LTEVPVPTRFLF+LLGP GKA YHEIGR+IATLM+DE+FH
Sbjct: 439 LERPIIAFVRLAPAVLLTGLTEVPVPTRFLFLLLGPAGKAPQYHEIGRSIATLMTDEIFH 498
Query: 311 DIAYKAKDRHDLIAGIDEFLDEVIVLPPGEWDPAIRIEPPKSLPSSDKRKNMYSGGENVQ 370
D+AYKAKDR+DL++GIDEFLD+V VLPPGEWDP+IRIEPPKS+PS +KRK +
Sbjct: 499 DVAYKAKDRNDLLSGIDEFLDQVTVLPPGEWDPSIRIEPPKSVPSQEKRKIPVFHNGSTP 558
Query: 371 MNGDTPHDGGHGGGGHGDCEELQRTGRFCGGLIKDIKRKAPFFASDFYDALNIQALSAIL 430
G+TP + H G ELQRTGR GGLI DIKRKAPFF SDF DAL++Q L++IL
Sbjct: 559 TLGETPKEAAHHAG-----PELQRTGRLFGGLILDIKRKAPFFLSDFKDALSLQCLASIL 613
Query: 431 FIYLATVTNAITFGGLLGDATDNMQGVLESFLGTAVSGAIFCLFAGQPLTILSSTGPVLV 490
F+Y A ++ ITFGGLLG+AT+ +ES G +++G + LFAGQPLTIL STGPVLV
Sbjct: 614 FLYCACMSPVITFGGLLGEATEGRISAIESLFGASLTGIAYSLFAGQPLTILGSTGPVLV 673
Query: 491 FERLLFNFSKDNNFDYLEFRLWIGLWSAFLCLILVATDASFLVQYFTRFTEEGFSSLISF 550
FE++L+ F +D YL R IGLW++FLC++LVATDAS LV Y TRFTEE F++LI
Sbjct: 674 FEKILYKFCRDYQLSYLSLRTSIGLWTSFLCIVLVATDASSLVCYITRFTEEAFAALICI 733
Query: 551 IFIYDAFKKMIKLADYYPINSNFKVGYNTLFSCTCV-PPDPANISISNDTTLAPEYLPTM 609
IFIY+A +K+ L + Y N + + T +SC C PP+P+N TLA +
Sbjct: 734 IFIYEALEKLFDLGETYAFNMHNNLDKLTSYSCVCTEPPNPSN------ETLAQWKKDNI 787
Query: 610 SSTDMYHNTTFDWAFLSKKECSKYGGNLVGNNCN----FVPDITLMSFILFLGTYTSSMA 665
++ HN + W L+ EC K G +G+ C ++PD+ ILF T+ S
Sbjct: 788 TA----HNIS--WRNLTVSECKKLRGVFLGSACGHHGPYIPDVLFWCVILFFTTFFLSSF 841
Query: 666 LKKFKTSPYFPTTARKLISDFAIILSILIFCVIDALVGVDTPKLIVPSEFKPTSPNRGWF 725
LK+FKT YFPT R ISDFA+ L+I+I ID LVGV +PKL VP +F+PT P RGW
Sbjct: 842 LKQFKTKRYFPTKVRSTISDFAVFLTIVIMVTIDYLVGVPSPKLHVPEKFEPTHPERGWI 901
Query: 726 VPPFGENPWWVCLAAAIPALLVTILIFMDQQITAVIVNRKEHKLKKGAGYHLDLFWVAIL 785
+ P G+NPWW L AAIPALL TILIFMDQQITAVI+NRKEHKLKKGAGYHLDL V ++
Sbjct: 902 ISPLGDNPWWTLLIAAIPALLCTILIFMDQQITAVIINRKEHKLKKGAGYHLDLLMVGVM 961
Query: 786 MVICSLMALPWYVAATVISIAHIDSLKMETETSAPGEQPKFLGVREQRVTGTLVFILTGL 845
+ +CS+M LPW+VAATV+SI+H++SLK+E+E SAPGEQPKFLG+REQRVTG ++FIL GL
Sbjct: 962 LGVCSVMGLPWFVAATVLSISHVNSLKVESECSAPGEQPKFLGIREQRVTGLMIFILMGL 1021
Query: 846 SVFMAPILKFIPMPVLYGVFLYMGVASLNGVQFMDRLKLLLMPLKHQPDFIYLRHVPLRR 905
SVFM +LKFIPMPVLYGVFLYMGV+SL G+Q DR+KL MP KHQPD IYLR+VPL +
Sbjct: 1022 SVFMTSVLKFIPMPVLYGVFLYMGVSSLKGIQLFDRIKLFGMPAKHQPDLIYLRYVPLWK 1081
Query: 906 VHLFTFLQVLCLALLWILKSTVAAIIFPVMILALVAVRKGMDYLFSQHDLSFLDDVIPEK 965
VH+FT +Q+ CL LLW++K + AA++FP+M+LALV VRK MD F++ +LS+LDD++PE
Sbjct: 1082 VHIFTVIQLTCLVLLWVIKVSAAAVVFPMMVLALVFVRKLMDLCFTKRELSWLDDLMPES 1141
Query: 966 DKKKKEDEKKKKKKKGS--LDSDNDDSDCPYSEKVPSIKIPMDIMEQQP 1012
KKK++D+KKK+K++ L D+D P+ E ++IP+ ++ P
Sbjct: 1142 KKKKEDDKKKKEKEEAERMLQDDDDTVHLPF-EGGSLLQIPVKALKYSP 1189
Score = 167 bits (424), Expect = 4e-41
Identities = 89/186 (47%), Positives = 123/186 (66%), Gaps = 9/186 (4%)
Query: 45 AERIRFILGEEDDSPA--PPQLFTELDELLAVDGQEMEWKETARWIKFEEKVEQGGERWS 102
++R++FILG EDD P LFTE+DEL DG+E EWKETARW+KFEE VE GG+RWS
Sbjct: 91 SQRVQFILGTEDDDEEHIPHDLFTEMDELCYRDGEEYEWKETARWLKFEEDVEDGGDRWS 150
Query: 103 KPHVATLSLHSLFELRTCMEKGSIMLDREASSLPQLVEMIVDHQIETGLLKPELKDKVTY 162
KP+VATLSLHSLFELR+C+ G++MLD AS+L ++ +M++D+ I +G L +++ V
Sbjct: 151 KPYVATLSLHSLFELRSCILNGTVMLDMRASTLDEIADMVLDNMIASGQLDESIRENVRE 210
Query: 163 TLLRKHRHQTKK------SNLRSLADIGKTVSSASRMFTNPDNGSPAMTHRNLTSSSLND 216
LL++H HQ +K +RS ADIGK S + N + G A H T S ++
Sbjct: 211 ALLKRHHHQNEKRFTSRIPLVRSFADIGKKHSDPHLLERNGE-GLSASRHSLRTGLSASN 269
Query: 217 ISDKPE 222
+S + E
Sbjct: 270 LSLRGE 275
>gi|156071474 solute carrier family 4, anion exchanger, member 2
(erythrocyte membrane protein band 3-like 1) [Homo
sapiens]
Length = 1241
Score = 658 bits (1697), Expect = 0.0
Identities = 376/945 (39%), Positives = 552/945 (58%), Gaps = 63/945 (6%)
Query: 61 PPQLFTELDELLAVDGQEMEWKETARWIKFEEKVEQGGERWSKPHVATLSLHSLFELRTC 120
P ++F EL+ELL QE +W+ETARWIKFEE VE+ ERW KPHVA+LS SL ELR
Sbjct: 320 PHEVFVELNELLLDKNQEPQWRETARWIKFEEDVEEETERWGKPHVASLSFRSLLELRRT 379
Query: 121 MEKGSIMLDREASSLPQLVEMIVDHQIETGLLKPELKDKVTYTLLRKHRHQTKKSNLR-- 178
+ G+++LD + +LP + +V+ + + +K E + V LL KH H + + +
Sbjct: 380 LAHGAVLLDLDQQTLPGVAHQVVEQMVISDQIKAEDRANVLRALLLKHSHPSDEKDFSFP 439
Query: 179 ---SLADIGKTVSS--ASRMFTNPDNGSPAMTHRNLTSSSLNDISDKP----------EK 223
S +G + ++P P M T + + P K
Sbjct: 440 RNISAGSLGSLLGHHHGQGAESDPHVTEPLMGGVPETRLEVERERELPPPAPPAGITRSK 499
Query: 224 DQLKNKFMKKLPRDAEASNVLVGEVDFLDTPFIAFVRLQQAVMLGALTEVPVPTRFLFIL 283
+ + K ++K+P +AEA+ VLVG V+FL P +AFVRL++AV L A+ EVPVP RFLF+L
Sbjct: 500 SKHELKLLEKIPENAEATVVLVGCVEFLSRPTMAFVRLREAVELDAVLEVPVPVRFLFLL 559
Query: 284 LGPKGKAKSYHEIGRAIATLMSDEVFHDIAYKAKDRHDLIAGIDEFLDEVIVLPPGEWDP 343
LGP YHEIGR+I+TLMSD+ FH+ AY A +R DL+ I+ FLD +VLPP E
Sbjct: 560 LGPSSANMDYHEIGRSISTLMSDKQFHEAAYLADEREDLLTAINAFLDCSVVLPPSEVQG 619
Query: 344 AIRIEPPKSLPSSDKRKNMYSGGENVQMNGDTPHDGGHGG-------GGHGDCEELQRTG 396
+ +K G G P G + + L+RTG
Sbjct: 620 EELLRSVAHFQRQMLKKREEQGRLLPTGAGLEPKSAQDKALLQMVEAAGAAEDDPLRRTG 679
Query: 397 RFCGGLIKDIKRKAPFFASDFYDALNIQALSAILFIYLATVTNAITFGGLLGDATDNMQG 456
R GGLI+D++R+ P + SDF DAL+ Q L+A++FIY A ++ AITFGGLLG+ T ++ G
Sbjct: 680 RPFGGLIRDVRRRYPHYLSDFRDALDPQCLAAVIFIYFAALSPAITFGGLLGEKTQDLIG 739
Query: 457 VLESFLGTAVSGAIFCLFAGQPLTILSSTGPVLVFERLLFNFSKDNNFDYLEFRLWIGLW 516
V E + TA+ G +FCL QPL ++ +GP+LVFE F+F N+ +YL R+WIG W
Sbjct: 740 VSELIMSTALQGVVFCLLGAQPLLVIGFSGPLLVFEEAFFSFCSSNHLEYLVGRVWIGFW 799
Query: 517 SAFLCLILVATDASFLVQYFTRFTEEGFSSLISFIFIYDAFKKMIKLADYYPINSNFKVG 576
FL L++VA + SFLV++ +RFT+E F+ LIS IFIY+ F K++K+ +P++
Sbjct: 800 LVFLALLMVALEGSFLVRFVSRFTQEIFAFLISLIFIYETFYKLVKIFQEHPLHG----- 854
Query: 577 YNTLFSCTCVPPDPANISISNDTTLAPEYLPTMSSTDMYHNTTFDWAFLSKKECSKYGGN 636
C + + + + T A PT+ + + + K G
Sbjct: 855 --------CSASNSSEVDGGENMTWAGAR-PTLGPGNR--------SLAGQSGQGKPRGQ 897
Query: 637 LVGNNCNFVPDITLMSFILFLGTYTSSMALKKFKTSPYFPTTARKLISDFAIILSILIFC 696
P+ L+S +L GT+ + L+KFK S +FP R++I DF + ++ILI
Sbjct: 898 ---------PNTALLSLVLMAGTFFIAFFLRKFKNSRFFPGRIRRVIGDFGVPIAILIMV 948
Query: 697 VID-ALVGVDTPKLIVPSEFKPTSPN-RGWFVPPFGEN---PWWVCLAAAIPALLVTILI 751
++D ++ T KL VPS F T+P RGW + P GE P W+ +A+ +PA+LV ILI
Sbjct: 949 LVDYSIEDTYTQKLSVPSGFSVTAPEKRGWVINPLGEKSPFPVWMMVASLLPAILVFILI 1008
Query: 752 FMDQQITAVIVNRKEHKLKKGAGYHLDLFWVAILMVICSLMALPWYVAATVISIAHIDSL 811
FM+ QIT +I+++KE L+KG+G+HLDL + + IC+L LPW AATV S+ H ++L
Sbjct: 1009 FMETQITTLIISKKERMLQKGSGFHLDLLLIVAMGGICALFGLPWLAAATVRSVTHANAL 1068
Query: 812 KMETETSAPGEQPKFLGVREQRVTGTLVFILTGLSVFMAPILKFIPMPVLYGVFLYMGVA 871
+ ++ APG++PK V+EQRVTG LV +L GLS+ + +L+ IP+ VL+G+FLYMGV
Sbjct: 1069 TVMSKAVAPGDKPKIQEVKEQRVTGLLVALLVGLSIVIGDLLRQIPLAVLFGIFLYMGVT 1128
Query: 872 SLNGVQFMDRLKLLLMPLKHQPDFIYLRHVPLRRVHLFTFLQVLCLALLWILKSTVAAII 931
SLNG+QF +RL LLLMP KH PD Y++ V R+HLFT LQ+LCLALLW + ST A++
Sbjct: 1129 SLNGIQFYERLHLLLMPPKHHPDVTYVKKVRTLRMHLFTALQLLCLALLWAVMSTAASLA 1188
Query: 932 FPVMILALVAVRK-GMDYLFSQHDLSFLD--DVIPEKDKKKKEDE 973
FP +++ V +R + +F+ ++ LD + P D+++ DE
Sbjct: 1189 FPFILILTVPLRMVVLTRIFTDREMKCLDANEAEPVFDEREGVDE 1233
>gi|157671951 solute carrier family 4, anion exchanger, member 3
isoform 1 [Homo sapiens]
Length = 1232
Score = 647 bits (1669), Expect = 0.0
Identities = 385/953 (40%), Positives = 547/953 (57%), Gaps = 87/953 (9%)
Query: 61 PPQLFTELDELLAVDGQEMEWKETARWIKFEEKVEQGGERWSKPHVATLSLHSLFELRTC 120
P ++F EL+EL+ QE W+ETARWIKFEE VE+ ERW KPHVA+LS SL ELR
Sbjct: 318 PHEVFVELNELMLDRSQEPHWRETARWIKFEEDVEEETERWGKPHVASLSFRSLLELRRT 377
Query: 121 MEKGSIMLDREASSLPQLVEMIVDHQIETGLLKPELKDKVTYTLLRKHRHQTKKSNLRSL 180
+ G+ +LD E ++LP + ++V+ I + ++PE + V TLL KH H +
Sbjct: 378 IAHGAALLDLEQTTLPGIAHLVVETMIVSDQIRPEDRASVLRTLLLKHSHPNDDKD-SGF 436
Query: 181 ADIGKTVSSASRMFTN--------PDNGSPAMTHRNLTSSSL----NDISDKP------E 222
+ SS + + N PD P M + L D +KP +
Sbjct: 437 FPRNPSSSSMNSVLGNHHPTPSHGPDGAVPTMADDLGEPAPLWPHDPDAKEKPLHMPGGD 496
Query: 223 KDQLKN-KFMKKLPRDAEASNVLVGEVDFLDTPFIAFVRLQQAVMLGALTEVPVPTRFLF 281
+ K+ K ++K+P DAEA+ VLVG V FL+ P AFVRL +AV+L ++ EVPVP RFLF
Sbjct: 497 GHRGKSLKLLEKIPEDAEATVVLVGCVPFLEQPAAAFVRLNEAVLLESVLEVPVPVRFLF 556
Query: 282 ILLGPKGKAKSYHEIGRAIATLMSDEVFHDIAYKAKDRHDLIAGIDEFLDEVIVLPPGEW 341
++LGP + YHE+GR+IATLMSD++FH+ AY+A DR DL++ I EFLD IV+PP E
Sbjct: 557 VMLGPSHTSTDYHELGRSIATLMSDKLFHEAAYQADDRQDLLSAISEFLDGSIVIPPSEV 616
Query: 342 DPAIRIEPPKSLPSSDKRKNMYSGGENVQMNGDTPHDGGHG----------GGGHGDCEE 391
+ + + RK E Q + GG+ GG E+
Sbjct: 617 EGRDLLRSVAAFQRELLRKRR----EREQTKVEMTTRGGYTAPGKELSLELGGSEATPED 672
Query: 392 --LQRTGRFCGGLIKDIKRKAPFFASDFYDALNIQALSAILFIYLATVTNAITFGGLLGD 449
L RTG GGL++D++R+ P + SD DAL+ Q ++A+LFIY A ++ AITFGGLLG+
Sbjct: 673 DPLLRTGSVFGGLVRDVRRRYPHYPSDLRDALHSQCVAAVLFIYFAALSPAITFGGLLGE 732
Query: 450 ATDNMQGVLESFLGTAVSGAIFCLFAGQPLTILSSTGPVLVFERLLFNFSKDNNFDYLEF 509
T+ + GV E + TAV G +F L QPL ++ +GP+LVFE F F + + +YL
Sbjct: 733 KTEGLMGVSELIVSTAVLGVLFSLLGAQPLLVVGFSGPLLVFEEAFFKFCRAQDLEYLTG 792
Query: 510 RLWIGLWSAFLCLILVATDASFLVQYFTRFTEEGFSSLISFIFIYDAFKKMIKLADYYPI 569
R+W+GLW L LVA + SFLV+Y + FT+E F+ LIS IFIY+ F K+ K+ +P+
Sbjct: 793 RVWVGLWLVVFVLALVAAEGSFLVRYISPFTQEIFAFLISLIFIYETFYKLYKVFTEHPL 852
Query: 570 NSNFKVGYNTLFSCTCVPPDPANISISNDTTLAP--EYLPTMSSTDMYHNTTFDWAFLSK 627
+ PP+ A + S D L P LP N
Sbjct: 853 LPFY-------------PPEGA-LEGSLDAGLEPNGSALPPTEGPPSPRNQ--------- 889
Query: 628 KECSKYGGNLVGNNCNFVPDITLMSFILFLGTYTSSMALKKFKTSPYFPTTARKLISDFA 687
P+ L+S IL LGT+ + L+KF+ S + AR++I DF
Sbjct: 890 ------------------PNTALLSLILMLGTFFIAFFLRKFRNSRFLGGKARRIIGDFG 931
Query: 688 IILSILIFCVID-ALVGVDTPKLIVPSEFKPTSPN-RGWFVPPFGEN---PWWVCLAAAI 742
I +SIL+ ++D ++ T KL VP+ TSP+ R WF+PP G P W+ +AAA+
Sbjct: 932 IPISILVMVLVDYSITDTYTQKLTVPTGLSVTSPDKRSWFIPPLGSARPFPPWMMVAAAV 991
Query: 743 PALLVTILIFMDQQITAVIVNRKEHKLKKGAGYHLDLFWVAILMVICSLMALPWYVAATV 802
PALLV ILIFM+ QITA+IV++K +L KG+G+HLDL + L +C L LPW AATV
Sbjct: 992 PALLVLILIFMETQITALIVSQKARRLLKGSGFHLDLLLIGSLGGLCGLFGLPWLTAATV 1051
Query: 803 ISIAHIDSLKMETETSAPGEQPKFLGVREQRVTGTLVFILTGLSVFMAPILKFIPMPVLY 862
S+ H+++L + APG++P+ VREQRVTG L+ L GLS+ M +L+ IP+ VL+
Sbjct: 1052 RSVTHVNALTVMRTAIAPGDKPQIQEVREQRVTGVLIASLVGLSIVMGAVLRRIPLAVLF 1111
Query: 863 GVFLYMGVASLNGVQFMDRLKLLLMPLKHQPDFIYLRHVPLRRVHLFTFLQVLCLALLWI 922
G+FLYMGV SL+G+Q RL L+LMP KH P+ Y+ V R+HLFT +Q+ C+ALLW+
Sbjct: 1112 GIFLYMGVTSLSGIQLSQRLLLILMPAKHHPEQPYVTKVKTWRMHLFTCIQLGCIALLWV 1171
Query: 923 LKSTVAAIIFPVMILALVAVRKG-MDYLFSQHDLSFLD--DVIPEKDKKKKED 972
+KST A++ FP ++L V +R + LF +L LD D P D+ +++
Sbjct: 1172 VKSTAASLAFPFLLLLTVPLRHCLLPRLFQDRELQALDSEDAEPNFDEDGQDE 1224
>gi|157671953 solute carrier family 4, anion exchanger, member 3
isoform 2 [Homo sapiens]
Length = 1259
Score = 647 bits (1669), Expect = 0.0
Identities = 385/953 (40%), Positives = 547/953 (57%), Gaps = 87/953 (9%)
Query: 61 PPQLFTELDELLAVDGQEMEWKETARWIKFEEKVEQGGERWSKPHVATLSLHSLFELRTC 120
P ++F EL+EL+ QE W+ETARWIKFEE VE+ ERW KPHVA+LS SL ELR
Sbjct: 345 PHEVFVELNELMLDRSQEPHWRETARWIKFEEDVEEETERWGKPHVASLSFRSLLELRRT 404
Query: 121 MEKGSIMLDREASSLPQLVEMIVDHQIETGLLKPELKDKVTYTLLRKHRHQTKKSNLRSL 180
+ G+ +LD E ++LP + ++V+ I + ++PE + V TLL KH H +
Sbjct: 405 IAHGAALLDLEQTTLPGIAHLVVETMIVSDQIRPEDRASVLRTLLLKHSHPNDDKD-SGF 463
Query: 181 ADIGKTVSSASRMFTN--------PDNGSPAMTHRNLTSSSL----NDISDKP------E 222
+ SS + + N PD P M + L D +KP +
Sbjct: 464 FPRNPSSSSMNSVLGNHHPTPSHGPDGAVPTMADDLGEPAPLWPHDPDAKEKPLHMPGGD 523
Query: 223 KDQLKN-KFMKKLPRDAEASNVLVGEVDFLDTPFIAFVRLQQAVMLGALTEVPVPTRFLF 281
+ K+ K ++K+P DAEA+ VLVG V FL+ P AFVRL +AV+L ++ EVPVP RFLF
Sbjct: 524 GHRGKSLKLLEKIPEDAEATVVLVGCVPFLEQPAAAFVRLNEAVLLESVLEVPVPVRFLF 583
Query: 282 ILLGPKGKAKSYHEIGRAIATLMSDEVFHDIAYKAKDRHDLIAGIDEFLDEVIVLPPGEW 341
++LGP + YHE+GR+IATLMSD++FH+ AY+A DR DL++ I EFLD IV+PP E
Sbjct: 584 VMLGPSHTSTDYHELGRSIATLMSDKLFHEAAYQADDRQDLLSAISEFLDGSIVIPPSEV 643
Query: 342 DPAIRIEPPKSLPSSDKRKNMYSGGENVQMNGDTPHDGGHG----------GGGHGDCEE 391
+ + + RK E Q + GG+ GG E+
Sbjct: 644 EGRDLLRSVAAFQRELLRKRR----EREQTKVEMTTRGGYTAPGKELSLELGGSEATPED 699
Query: 392 --LQRTGRFCGGLIKDIKRKAPFFASDFYDALNIQALSAILFIYLATVTNAITFGGLLGD 449
L RTG GGL++D++R+ P + SD DAL+ Q ++A+LFIY A ++ AITFGGLLG+
Sbjct: 700 DPLLRTGSVFGGLVRDVRRRYPHYPSDLRDALHSQCVAAVLFIYFAALSPAITFGGLLGE 759
Query: 450 ATDNMQGVLESFLGTAVSGAIFCLFAGQPLTILSSTGPVLVFERLLFNFSKDNNFDYLEF 509
T+ + GV E + TAV G +F L QPL ++ +GP+LVFE F F + + +YL
Sbjct: 760 KTEGLMGVSELIVSTAVLGVLFSLLGAQPLLVVGFSGPLLVFEEAFFKFCRAQDLEYLTG 819
Query: 510 RLWIGLWSAFLCLILVATDASFLVQYFTRFTEEGFSSLISFIFIYDAFKKMIKLADYYPI 569
R+W+GLW L LVA + SFLV+Y + FT+E F+ LIS IFIY+ F K+ K+ +P+
Sbjct: 820 RVWVGLWLVVFVLALVAAEGSFLVRYISPFTQEIFAFLISLIFIYETFYKLYKVFTEHPL 879
Query: 570 NSNFKVGYNTLFSCTCVPPDPANISISNDTTLAP--EYLPTMSSTDMYHNTTFDWAFLSK 627
+ PP+ A + S D L P LP N
Sbjct: 880 LPFY-------------PPEGA-LEGSLDAGLEPNGSALPPTEGPPSPRNQ--------- 916
Query: 628 KECSKYGGNLVGNNCNFVPDITLMSFILFLGTYTSSMALKKFKTSPYFPTTARKLISDFA 687
P+ L+S IL LGT+ + L+KF+ S + AR++I DF
Sbjct: 917 ------------------PNTALLSLILMLGTFFIAFFLRKFRNSRFLGGKARRIIGDFG 958
Query: 688 IILSILIFCVID-ALVGVDTPKLIVPSEFKPTSPN-RGWFVPPFGEN---PWWVCLAAAI 742
I +SIL+ ++D ++ T KL VP+ TSP+ R WF+PP G P W+ +AAA+
Sbjct: 959 IPISILVMVLVDYSITDTYTQKLTVPTGLSVTSPDKRSWFIPPLGSARPFPPWMMVAAAV 1018
Query: 743 PALLVTILIFMDQQITAVIVNRKEHKLKKGAGYHLDLFWVAILMVICSLMALPWYVAATV 802
PALLV ILIFM+ QITA+IV++K +L KG+G+HLDL + L +C L LPW AATV
Sbjct: 1019 PALLVLILIFMETQITALIVSQKARRLLKGSGFHLDLLLIGSLGGLCGLFGLPWLTAATV 1078
Query: 803 ISIAHIDSLKMETETSAPGEQPKFLGVREQRVTGTLVFILTGLSVFMAPILKFIPMPVLY 862
S+ H+++L + APG++P+ VREQRVTG L+ L GLS+ M +L+ IP+ VL+
Sbjct: 1079 RSVTHVNALTVMRTAIAPGDKPQIQEVREQRVTGVLIASLVGLSIVMGAVLRRIPLAVLF 1138
Query: 863 GVFLYMGVASLNGVQFMDRLKLLLMPLKHQPDFIYLRHVPLRRVHLFTFLQVLCLALLWI 922
G+FLYMGV SL+G+Q RL L+LMP KH P+ Y+ V R+HLFT +Q+ C+ALLW+
Sbjct: 1139 GIFLYMGVTSLSGIQLSQRLLLILMPAKHHPEQPYVTKVKTWRMHLFTCIQLGCIALLWV 1198
Query: 923 LKSTVAAIIFPVMILALVAVRKG-MDYLFSQHDLSFLD--DVIPEKDKKKKED 972
+KST A++ FP ++L V +R + LF +L LD D P D+ +++
Sbjct: 1199 VKSTAASLAFPFLLLLTVPLRHCLLPRLFQDRELQALDSEDAEPNFDEDGQDE 1251
>gi|4507021 solute carrier family 4, anion exchanger, member 1 [Homo
sapiens]
Length = 911
Score = 564 bits (1453), Expect = e-160
Identities = 341/933 (36%), Positives = 517/933 (55%), Gaps = 99/933 (10%)
Query: 59 PAPPQLFTELDELLAVD-GQEMEWKETARWIKFEEKVEQGGERWSKPHVATLSLHSLFEL 117
P +++ EL EL+ + QE+ W E ARW++ EE + + G W +PH++ L+ SL EL
Sbjct: 52 PGTHKVYVELQELVMDEKNQELRWMEAARWVQLEENLGENGA-WGRPHLSHLTFWSLLEL 110
Query: 118 RTCMEKGSIMLDREASSLPQLVEMIVDHQIETGLLKPELKDKVTYTLLRKHRHQTKKSNL 177
R KG+++LD + +SL + ++D I ++P+ ++++ LL KH H L
Sbjct: 111 RRVFTKGTVLLDLQETSLAGVANQLLDRFIFEDQIRPQDREELLRALLLKHSHA---GEL 167
Query: 178 RSLADIGKTVSSASRMFTNPDNGSPAMT-HRNLTSSSLNDISDKPEKDQLKNKFMKKLPR 236
+L + V + S D P + H +L + + D + + ++K+P
Sbjct: 168 EALGGVKPAVLTRSG-----DPSQPLLPQHSSLETQLFCEQGDGGTEGHSPSGILEKIPP 222
Query: 237 DAEASNVLVGEVDFLDTPFIAFVRLQQAVMLGALTEVPVPTRFLFILLGPKGKAKSYHEI 296
D+EA+ VLVG DFL+ P + FVRLQ+A L A+ E+PVP RFLF+LLGP+ Y ++
Sbjct: 223 DSEATLVLVGRADFLEQPVLGFVRLQEAAELEAV-ELPVPIRFLFVLLGPEAPHIDYTQL 281
Query: 297 GRAIATLMSDEVFHDIAYKAKDRHDLIAGIDEFLDEVIVLPPGEWDPA--------IRIE 348
GRA ATLMS+ VF AY A+ R +L+ ++ FLD +VLPP + ++ E
Sbjct: 282 GRAAATLMSERVFRIDAYMAQSRGELLHSLEGFLDCSLVLPPTDAPSEQALLSLVPVQRE 341
Query: 349 PPKSLPSSDKRKNMYSGGENVQMNGDTPHDGGHGGGGHGDCEELQRTGRFCGGLIKDIKR 408
+ S K S + + +NG G + LQ+TG+ GGL++DI+R
Sbjct: 342 LLRRRYQSSPAKPDSSFYKGLDLNG-------------GPDDPLQQTGQLFGGLVRDIRR 388
Query: 409 KAPFFASDFYDALNIQALSAILFIYLATVTNAITFGGLLGDATDNMQGVLESFLGTAVSG 468
+ P++ SD DA + Q L+A++FIY A ++ AITFGGLLG+ T N GV E + TAV G
Sbjct: 389 RYPYYLSDITDAFSPQVLAAVIFIYFAALSPAITFGGLLGEKTRNQMGVSELLISTAVQG 448
Query: 469 AIFCLFAGQPLTILSSTGPVLVFERLLFNFSKDNNFDYLEFRLWIGLWSAFLCLILVATD 528
+F L QPL ++ +GP+LVFE F+F + N +Y+ R+WIG W L +++VA +
Sbjct: 449 ILFALLGAQPLLVVGFSGPLLVFEEAFFSFCETNGLEYIVGRVWIGFWLILLVVLVVAFE 508
Query: 529 ASFLVQYFTRFTEEGFSSLISFIFIYDAFKKMIKLADYYPINSNFKVGYNTLFSCTCVPP 588
SFLV++ +R+T+E FS LIS IFIY+ F K+IK+ +P+ + YN L P
Sbjct: 509 GSFLVRFISRYTQEIFSFLISLIFIYETFSKLIKIFQDHPLQKTY--NYNVLMVPKPQGP 566
Query: 589 DPANISISNDTTLAPEYLPTMSSTDMYHNTTFDWAFLSKKECSKYGGNLVGNNCNFVPDI 648
P +S L M+ TF +A + +K
Sbjct: 567 LPNTALLS---------LVLMAG-------TFFFAMMLRK-------------------- 590
Query: 649 TLMSFILFLGTYTSSMALKKFKTSPYFPTTARKLISDFAIILSILIFCVIDALV-GVDTP 707
FK S YFP R++I DF + +SILI ++D + T
Sbjct: 591 --------------------FKNSSYFPGKLRRVIGDFGVPISILIMVLVDFFIQDTYTQ 630
Query: 708 KLIVPSEFK-PTSPNRGWFVPPFG---ENPWWVCLAAAIPALLVTILIFMDQQITAVIVN 763
KL VP FK S RGW + P G E P W+ A+A+PALLV ILIF++ QIT +IV+
Sbjct: 631 KLSVPDGFKVSNSSARGWVIHPLGLRSEFPIWMMFASALPALLVFILIFLESQITTLIVS 690
Query: 764 RKEHKLKKGAGYHLDLFWVAILMVICSLMALPWYVAATVISIAHIDSLKMETETSAPGEQ 823
+ E K+ KG+G+HLDL V + + +L +PW A TV S+ H ++L + + S PG
Sbjct: 691 KPERKMVKGSGFHLDLLLVVGMGGVAALFGMPWLSATTVRSVTHANALTVMGKASTPGAA 750
Query: 824 PKFLGVREQRVTGTLVFILTGLSVFMAPILKFIPMPVLYGVFLYMGVASLNGVQFMDRLK 883
+ V+EQR++G LV +L GLS+ M PIL IP+ VL+G+FLYMGV SL+G+Q DR+
Sbjct: 751 AQIQEVKEQRISGLLVAVLVGLSILMEPILSRIPLAVLFGIFLYMGVTSLSGIQLFDRIL 810
Query: 884 LLLMPLKHQPDFIYLRHVPLRRVHLFTFLQVLCLALLWILKSTVAAIIFPVMILALVAVR 943
LL P K+ PD Y++ V R+HLFT +Q++CLA+LW++KST A++ P +++ V +R
Sbjct: 811 LLFKPPKYHPDVPYVKRVKTWRMHLFTGIQIICLAVLWVVKSTPASLALPFVLILTVPLR 870
Query: 944 KG-MDYLFSQHDLSFL--DDVIPEKDKKKKEDE 973
+ + +F +L L DD D+++ DE
Sbjct: 871 RVLLPLIFRNVELQCLDADDAKATFDEEEGRDE 903
>gi|14042960 solute carrier family 4 member 11 [Homo sapiens]
Length = 891
Score = 231 bits (589), Expect = 3e-60
Identities = 184/681 (27%), Positives = 310/681 (45%), Gaps = 74/681 (10%)
Query: 278 RFLFILLGPKG--KAKSYHEIGRAIATLMSDEVFHDIAYKAKDRHDLIAGIDEFLDEVIV 335
RF+ ++L P K+ E+ R AT+ SD F + + + + + +
Sbjct: 248 RFVILVLAPPKMKSTKTAMEVARTFATMFSDIAFRQKLLETRTEEEFKEALVHQRQLLTM 307
Query: 336 LPPGEWDPAIRIEPPKSLPSSDKRKNMYSGGENVQMNGDTPHDGGHGGGGHGDCEELQRT 395
+ G P + SLP+ H C++
Sbjct: 308 VSHGPVAPRTKERSTVSLPA-------------------------HRHPEPPKCKDFVPF 342
Query: 396 GRFCGGLIKDIKRKAPFFASDFYDALNIQA------LSAILFIYLATVTNAITFGGLLGD 449
G+ G+ +DI R+ P + DF D + + ++ LF+Y A + I FG L +
Sbjct: 343 GK---GIREDIARRFPLYPLDFTDGIIGKNKAVGKYITTTLFLYFACLLPTIAFGSLNDE 399
Query: 450 ATDNMQGVLESFLGTAVSGAIFCLFAGQPLTILSSTGPVLVFERLLFNFSKDNNFDYLEF 509
TD V ++ G ++ G ++ LF+GQPL IL +T P+ ++ +++ D + D+ F
Sbjct: 400 NTDGAIDVQKTIAGQSIGGLLYALFSGQPLVILLTTAPLALYIQVIRVICDDYDLDFNSF 459
Query: 510 RLWIGLWSAFLCLILVATDASFLVQYFTRFTEEGFSSLISFIFIYDAFKKMIKLADYYPI 569
W GLW++F + + S ++ F R TEE + IS F+ DA K +K+ Y
Sbjct: 460 YAWTGLWNSFFLALYAFFNLSLVMSLFKRSTEEIIALFISITFVLDAVKGTVKIFWKY-Y 518
Query: 570 NSNFKVGYNTLFSCTCVPPDP--ANISISNDTTLAPEYLPTMSSTDMYHNTTFDWAFLSK 627
++ Y+T + + V A+++ S T L +L S T++ T A
Sbjct: 519 YGHYLDDYHTKRTSSLVSLSGLGASLNASLHTALNASFLA--SPTELPSATHSGQA---- 572
Query: 628 KECSKYGGNLVGNNCNFVPDITLMSFILFLGTYTSSMALKKFKTSPYFPTTARKLISDFA 687
++S ++ LGT L +FK SPY R+++SD A
Sbjct: 573 --------------------TAVLSLLIMLGTLWLGYTLYQFKKSPYLHPCVREILSDCA 612
Query: 688 IILSILIFCVIDALVGVDTPKLIVPSEFKPTSPNRGWFVPPFGENPWWVCLAAAIPALLV 747
+ +++L F +L+ + I S+F+ + + A L+
Sbjct: 613 LPIAVLAF----SLISSHGFREIEMSKFRYNPSESPFAMAQIQSLSLRAVSGAMGLGFLL 668
Query: 748 TILIFMDQQITAVIVNRKEHKLKKGAGYHLDLFWVAILMVICSLMALPWYVAATVISIAH 807
++L F++Q + A +VN E++L KG YH DL +AI+ SL LPW AA S H
Sbjct: 669 SMLFFIEQNLVAALVNAPENRLVKGTAYHWDLLLLAIINTGLSLFGLPWIHAAYPHSPLH 728
Query: 808 IDSLKMETETSAPGE-QPKFLGVREQRVTGTLVFILTGLSVFMAPI-LKFIPMPVLYGVF 865
+ +L + E G + V+E R+T +L GLS+ + P+ L++IP PVLYG+F
Sbjct: 729 VRALALVEERVENGHIYDTIVNVKETRLTSLGASVLVGLSLLLLPVPLQWIPKPVLYGLF 788
Query: 866 LYMGVASLNGVQFMDRLKLLLMPLKHQPDFIYLRHVPLRRVHLFTFLQVLCLALLWILKS 925
LY+ + SL+G Q + R+ LLL P Y+R VP R++H FT LQVL L LL
Sbjct: 789 LYIALTSLDGNQLVQRVALLLKEQTAYPPTHYIRRVPQRKIHYFTGLQVLQLLLLCAFGM 848
Query: 926 T---VAAIIFPVMILALVAVR 943
+ +IFP++++A++ +R
Sbjct: 849 SSLPYMKMIFPLIMIAMIPIR 869
>gi|169161027 PREDICTED: hypothetical protein [Homo sapiens]
Length = 219
Score = 35.8 bits (81), Expect = 0.21
Identities = 28/87 (32%), Positives = 38/87 (43%), Gaps = 14/87 (16%)
Query: 325 GIDEFLDEVIVLPPGEWDPAIRIEPPKSLPSSDKRKNMYSGGENVQMNGDTPHDGGH--- 381
G DEF+ +V+V+ PGE+ + P P+SD + GG V+ G G
Sbjct: 58 GDDEFIPQVLVVRPGEYQTLL----PARGPTSDPHHHPCPGGAPVRNTGSEDGSGSSSAA 113
Query: 382 ----GGGGHGDCE---ELQRTGRFCGG 401
G GGH + QRTGR G
Sbjct: 114 RKATGQGGHRLLQWVKAAQRTGRTIPG 140
>gi|113411962 PREDICTED: hypothetical protein [Homo sapiens]
Length = 254
Score = 35.8 bits (81), Expect = 0.21
Identities = 28/87 (32%), Positives = 38/87 (43%), Gaps = 14/87 (16%)
Query: 325 GIDEFLDEVIVLPPGEWDPAIRIEPPKSLPSSDKRKNMYSGGENVQMNGDTPHDGGH--- 381
G DEF+ +V+V+ PGE+ + P P+SD + GG V+ G G
Sbjct: 93 GDDEFIPQVLVVRPGEYQTLL----PARGPTSDPHHHPCPGGAPVRNTGSEDGSGSSSAA 148
Query: 382 ----GGGGHGDCE---ELQRTGRFCGG 401
G GGH + QRTGR G
Sbjct: 149 RKATGQGGHRLLQWVKAAQRTGRTIPG 175
>gi|113403778 PREDICTED: hypothetical protein [Homo sapiens]
Length = 219
Score = 35.8 bits (81), Expect = 0.21
Identities = 28/87 (32%), Positives = 38/87 (43%), Gaps = 14/87 (16%)
Query: 325 GIDEFLDEVIVLPPGEWDPAIRIEPPKSLPSSDKRKNMYSGGENVQMNGDTPHDGGH--- 381
G DEF+ +V+V+ PGE+ + P P+SD + GG V+ G G
Sbjct: 58 GDDEFIPQVLVVRPGEYQTLL----PARGPTSDPHHHPCPGGAPVRNTGSEDGSGSSSAA 113
Query: 382 ----GGGGHGDCE---ELQRTGRFCGG 401
G GGH + QRTGR G
Sbjct: 114 RKATGQGGHRLLQWVKAAQRTGRTIPG 140
>gi|24308089 chromodomain helicase DNA binding protein 5 [Homo
sapiens]
Length = 1954
Score = 35.0 bits (79), Expect = 0.37
Identities = 17/33 (51%), Positives = 22/33 (66%), Gaps = 1/33 (3%)
Query: 960 DVIPEKDKKKK-EDEKKKKKKKGSLDSDNDDSD 991
D P K KKKK +D+K+KK K+ D D DD+D
Sbjct: 92 DYSPNKKKKKKLKDKKEKKAKRKKKDEDEDDND 124
>gi|117553584 adaptor-related protein complex 3, delta 1 subunit
isoform 1 [Homo sapiens]
Length = 1112
Score = 34.7 bits (78), Expect = 0.48
Identities = 20/58 (34%), Positives = 33/58 (56%), Gaps = 9/58 (15%)
Query: 964 EKDK---KKKEDEKKKKKKKGSLDSDNDDSDCP------YSEKVPSIKIPMDIMEQQP 1012
EKDK K+KE EKK K++ SL +++D+ P +E++P +P D ++ P
Sbjct: 647 EKDKRRKKRKEKEKKGKRRHSSLPTESDEDIAPAQQVDIVTEEMPENALPSDEDDKDP 704
>gi|117553580 adaptor-related protein complex 3, delta 1 subunit
isoform 2 [Homo sapiens]
Length = 1153
Score = 34.7 bits (78), Expect = 0.48
Identities = 20/58 (34%), Positives = 33/58 (56%), Gaps = 9/58 (15%)
Query: 964 EKDK---KKKEDEKKKKKKKGSLDSDNDDSDCP------YSEKVPSIKIPMDIMEQQP 1012
EKDK K+KE EKK K++ SL +++D+ P +E++P +P D ++ P
Sbjct: 738 EKDKRRKKRKEKEKKGKRRHSSLPTESDEDIAPAQQVDIVTEEMPENALPSDEDDKDP 795
>gi|118498362 kinectin 1 isoform b [Homo sapiens]
Length = 1306
Score = 34.3 bits (77), Expect = 0.62
Identities = 23/82 (28%), Positives = 43/82 (52%), Gaps = 11/82 (13%)
Query: 961 VIPEKDKKKKEDEKKKKKKK---GSL-DSDNDD-------SDCPYSEKVPSIKIPMDIME 1009
+IP K KKK ++KK KKK+ G+L +SD++ SD E +P++++E
Sbjct: 47 LIPTKTDKKKAEKKKNKKKEIQNGNLHESDSESVPRDFKLSDALAVEDDQVAPVPLNVVE 106
Query: 1010 QQPFLSDSKPSDRERSPTFLER 1031
+ + K ++++ P E+
Sbjct: 107 TSSSVRERKKKEKKQKPVLEEQ 128
>gi|118498356 kinectin 1 isoform a [Homo sapiens]
Length = 1357
Score = 34.3 bits (77), Expect = 0.62
Identities = 23/82 (28%), Positives = 43/82 (52%), Gaps = 11/82 (13%)
Query: 961 VIPEKDKKKKEDEKKKKKKK---GSL-DSDNDD-------SDCPYSEKVPSIKIPMDIME 1009
+IP K KKK ++KK KKK+ G+L +SD++ SD E +P++++E
Sbjct: 47 LIPTKTDKKKAEKKKNKKKEIQNGNLHESDSESVPRDFKLSDALAVEDDQVAPVPLNVVE 106
Query: 1010 QQPFLSDSKPSDRERSPTFLER 1031
+ + K ++++ P E+
Sbjct: 107 TSSSVRERKKKEKKQKPVLEEQ 128
>gi|118498368 kinectin 1 isoform c [Homo sapiens]
Length = 1300
Score = 34.3 bits (77), Expect = 0.62
Identities = 23/82 (28%), Positives = 43/82 (52%), Gaps = 11/82 (13%)
Query: 961 VIPEKDKKKKEDEKKKKKKK---GSL-DSDNDD-------SDCPYSEKVPSIKIPMDIME 1009
+IP K KKK ++KK KKK+ G+L +SD++ SD E +P++++E
Sbjct: 47 LIPTKTDKKKAEKKKNKKKEIQNGNLHESDSESVPRDFKLSDALAVEDDQVAPVPLNVVE 106
Query: 1010 QQPFLSDSKPSDRERSPTFLER 1031
+ + K ++++ P E+
Sbjct: 107 TSSSVRERKKKEKKQKPVLEEQ 128
>gi|33620775 kinectin 1 isoform a [Homo sapiens]
Length = 1357
Score = 34.3 bits (77), Expect = 0.62
Identities = 23/82 (28%), Positives = 43/82 (52%), Gaps = 11/82 (13%)
Query: 961 VIPEKDKKKKEDEKKKKKKK---GSL-DSDNDD-------SDCPYSEKVPSIKIPMDIME 1009
+IP K KKK ++KK KKK+ G+L +SD++ SD E +P++++E
Sbjct: 47 LIPTKTDKKKAEKKKNKKKEIQNGNLHESDSESVPRDFKLSDALAVEDDQVAPVPLNVVE 106
Query: 1010 QQPFLSDSKPSDRERSPTFLER 1031
+ + K ++++ P E+
Sbjct: 107 TSSSVRERKKKEKKQKPVLEEQ 128
>gi|22902136 osterix [Homo sapiens]
Length = 431
Score = 33.5 bits (75), Expect = 1.1
Identities = 21/62 (33%), Positives = 30/62 (48%), Gaps = 9/62 (14%)
Query: 350 PKSLPSSDKRKNMYSGGENVQMNGDTPHDGGHGGGGHG-------DCEELQRTGRFCGGL 402
PK++ +S + + SGG T GG+GG G G +C+EL+R G GL
Sbjct: 231 PKAVGNSGQLEG--SGGAKPPRGASTGGSGGYGGSGAGRSSCDCPNCQELERLGAAAAGL 288
Query: 403 IK 404
K
Sbjct: 289 RK 290
>gi|42718020 retinitis pigmentosa 9 [Homo sapiens]
Length = 221
Score = 33.5 bits (75), Expect = 1.1
Identities = 14/28 (50%), Positives = 20/28 (71%)
Query: 964 EKDKKKKEDEKKKKKKKGSLDSDNDDSD 991
EK KK+K+++KKKKK+K N+ SD
Sbjct: 192 EKHKKRKKEKKKKKKRKHKSSKSNEGSD 219
>gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens]
Length = 1564
Score = 33.1 bits (74), Expect = 1.4
Identities = 17/35 (48%), Positives = 21/35 (60%), Gaps = 2/35 (5%)
Query: 963 PEKDKKKKEDEKKKKKKKGSLDSDNDDSDCPYSEK 997
P+K +KKK EKK+KK KG DSD D + K
Sbjct: 994 PKKGQKKKSIEKKRKKSKG--DSDISDEEAAQQSK 1026
>gi|27477111 step II splicing factor SLU7 [Homo sapiens]
Length = 586
Score = 32.7 bits (73), Expect = 1.8
Identities = 13/25 (52%), Positives = 21/25 (84%)
Query: 965 KDKKKKEDEKKKKKKKGSLDSDNDD 989
K++KKK+ +KKKK +K S DSD+++
Sbjct: 495 KEEKKKKKKKKKKHRKSSSDSDDEE 519
Score = 31.2 bits (69), Expect = 5.3
Identities = 14/28 (50%), Positives = 20/28 (71%)
Query: 964 EKDKKKKEDEKKKKKKKGSLDSDNDDSD 991
EK K++K+ +KKKKKK SD+DD +
Sbjct: 492 EKLKEEKKKKKKKKKKHRKSSSDSDDEE 519
>gi|56090620 NFKB activating protein-like [Homo sapiens]
Length = 402
Score = 32.7 bits (73), Expect = 1.8
Identities = 15/36 (41%), Positives = 20/36 (55%)
Query: 962 IPEKDKKKKEDEKKKKKKKGSLDSDNDDSDCPYSEK 997
+ K KKKK+ K KKKK ++ DS C SE+
Sbjct: 223 VKAKKKKKKKKHKTKKKKNKKTKKESSDSSCKDSEE 258
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.322 0.138 0.415
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 39,672,858
Number of Sequences: 37866
Number of extensions: 1847606
Number of successful extensions: 9244
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 35
Number of HSP's successfully gapped in prelim test: 35
Number of HSP's that attempted gapping in prelim test: 8648
Number of HSP's gapped (non-prelim): 461
length of query: 1035
length of database: 18,247,518
effective HSP length: 112
effective length of query: 923
effective length of database: 14,006,526
effective search space: 12928023498
effective search space used: 12928023498
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.