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Search of human proteins with 4506943
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4506943 short stature homeobox isoform SHOXa [Homo sapiens]
(292 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4506943 short stature homeobox isoform SHOXa [Homo sapiens] 587 e-168
gi|6031203 short stature homeobox isoform SHOXb [Homo sapiens] 431 e-121
gi|89145413 short stature homeobox 2 isoform a [Homo sapiens] 341 5e-94
gi|87044888 short stature homeobox 2 isoform b [Homo sapiens] 317 1e-86
gi|126116581 retina and anterior neural fold homeobox [Homo sapi... 105 6e-23
gi|24497589 aristaless related homeobox [Homo sapiens] 105 6e-23
gi|122937484 dorsal root ganglia homeobox [Homo sapiens] 99 6e-21
gi|4505619 paired box 7 isoform 1 [Homo sapiens] 97 2e-20
gi|7524359 paired box 7 isoform 2 [Homo sapiens] 97 2e-20
gi|207029223 paired box 7 isoform 3 [Homo sapiens] 97 2e-20
gi|188219638 paired box 3 isoform PAX3i [Homo sapiens] 96 4e-20
gi|31563348 paired box 3 isoform PAX3g [Homo sapiens] 96 4e-20
gi|31563346 paired box 3 isoform PAX3h [Homo sapiens] 96 4e-20
gi|31563344 paired box 3 isoform PAX3e [Homo sapiens] 96 4e-20
gi|31563342 paired box 3 isoform PAX3d [Homo sapiens] 96 4e-20
gi|31563340 paired box 3 isoform PAX3 [Homo sapiens] 96 4e-20
gi|7706659 paired related homeobox 2 [Homo sapiens] 96 5e-20
gi|4826912 paired-like homeodomain 3 [Homo sapiens] 95 6e-20
gi|5902024 paired mesoderm homeobox 1 isoform pmx-1a [Homo sapiens] 95 6e-20
gi|12707577 paired mesoderm homeobox 1 isoform pmx-1b [Homo sapi... 95 6e-20
gi|239754062 PREDICTED: orthopedia homeobox [Homo sapiens] 93 3e-19
gi|12707580 paired-like homeobox 2b [Homo sapiens] 93 3e-19
gi|46249382 paired-like homeobox 2a [Homo sapiens] 93 3e-19
gi|14149760 orthopedia homeobox [Homo sapiens] 93 3e-19
gi|14249388 retina and anterior neural fold homeobox 2 [Homo sap... 92 4e-19
gi|122937321 UNC homeobox [Homo sapiens] 92 7e-19
gi|55743092 aristaless-like homeobox 4 [Homo sapiens] 91 2e-18
gi|27436933 orthodenticle homeobox 2 isoform b [Homo sapiens] 90 2e-18
gi|11119420 orthodenticle homeobox 2 isoform a [Homo sapiens] 90 2e-18
gi|27436936 diencephalon/mesencephalon homeobox 1 isoform a [Hom... 89 6e-18
>gi|4506943 short stature homeobox isoform SHOXa [Homo sapiens]
Length = 292
Score = 587 bits (1514), Expect = e-168
Identities = 292/292 (100%), Positives = 292/292 (100%)
Query: 1 MEELTAFVSKSFDQKSKDGNGGGGGGGGKKDSITYREVLESGLARSRELGTSDSSLQDIT 60
MEELTAFVSKSFDQKSKDGNGGGGGGGGKKDSITYREVLESGLARSRELGTSDSSLQDIT
Sbjct: 1 MEELTAFVSKSFDQKSKDGNGGGGGGGGKKDSITYREVLESGLARSRELGTSDSSLQDIT 60
Query: 61 EGGGHCPVHLFKDHVDNDKEKLKEFGTARVAEGIYECKEKREDVKSEDEDGQTKLKQRRS 120
EGGGHCPVHLFKDHVDNDKEKLKEFGTARVAEGIYECKEKREDVKSEDEDGQTKLKQRRS
Sbjct: 61 EGGGHCPVHLFKDHVDNDKEKLKEFGTARVAEGIYECKEKREDVKSEDEDGQTKLKQRRS 120
Query: 121 RTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKCRKQENQMH 180
RTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKCRKQENQMH
Sbjct: 121 RTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKCRKQENQMH 180
Query: 181 KGVILGTANHLDACRVAPYVNMGALRMPFQQVQAQLQLEGVAHAHPHLHPHLAAHAPYLM 240
KGVILGTANHLDACRVAPYVNMGALRMPFQQVQAQLQLEGVAHAHPHLHPHLAAHAPYLM
Sbjct: 181 KGVILGTANHLDACRVAPYVNMGALRMPFQQVQAQLQLEGVAHAHPHLHPHLAAHAPYLM 240
Query: 241 FPPPPFGLPIASLAESASAAAVVAAAAKSNSKNSSIADLRLKARKHAEALGL 292
FPPPPFGLPIASLAESASAAAVVAAAAKSNSKNSSIADLRLKARKHAEALGL
Sbjct: 241 FPPPPFGLPIASLAESASAAAVVAAAAKSNSKNSSIADLRLKARKHAEALGL 292
>gi|6031203 short stature homeobox isoform SHOXb [Homo sapiens]
Length = 225
Score = 431 bits (1109), Expect = e-121
Identities = 211/213 (99%), Positives = 213/213 (100%)
Query: 1 MEELTAFVSKSFDQKSKDGNGGGGGGGGKKDSITYREVLESGLARSRELGTSDSSLQDIT 60
MEELTAFVSKSFDQKSKDGNGGGGGGGGKKDSITYREVLESGLARSRELGTSDSSLQDIT
Sbjct: 1 MEELTAFVSKSFDQKSKDGNGGGGGGGGKKDSITYREVLESGLARSRELGTSDSSLQDIT 60
Query: 61 EGGGHCPVHLFKDHVDNDKEKLKEFGTARVAEGIYECKEKREDVKSEDEDGQTKLKQRRS 120
EGGGHCPVHLFKDHVDNDKEKLKEFGTARVAEGIYECKEKREDVKSEDEDGQTKLKQRRS
Sbjct: 61 EGGGHCPVHLFKDHVDNDKEKLKEFGTARVAEGIYECKEKREDVKSEDEDGQTKLKQRRS 120
Query: 121 RTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKCRKQENQMH 180
RTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKCRKQENQMH
Sbjct: 121 RTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKCRKQENQMH 180
Query: 181 KGVILGTANHLDACRVAPYVNMGALRMPFQQVQ 213
KGVILGTANHLDACRVAPYVNMGALRMPFQQ++
Sbjct: 181 KGVILGTANHLDACRVAPYVNMGALRMPFQQME 213
>gi|89145413 short stature homeobox 2 isoform a [Homo sapiens]
Length = 331
Score = 341 bits (874), Expect = 5e-94
Identities = 201/353 (56%), Positives = 231/353 (65%), Gaps = 83/353 (23%)
Query: 1 MEELTAFVSKSFDQKSKD------------------------------------------ 18
MEELTAFVSKSFDQK K+
Sbjct: 1 MEELTAFVSKSFDQKVKEKKEAITYREVLESGPLRGAKEPTGCTEAGRDDRSSPAVRAAG 60
Query: 19 ---GNGGGGGGGGKKDSITYREVLESGLARSRELGTSDSSLQDITEGGGHCPVHLFKDHV 75
G GGGGGGGG G+ G + GGG PV ++
Sbjct: 61 GGGGGGGGGGGGGG----------GGGVGGGGAGGGA---------GGGRSPV---RELD 98
Query: 76 DNDKEKLKEFGTARVAEGIYECKEKREDVKSEDEDGQTKLKQRRSRTNFTLEQLNELERL 135
E+ +E G+ R+ E E K+++ED K +++GQTK+KQRRSRTNFTLEQLNELERL
Sbjct: 99 MGAAERSREPGSPRLTEVSPELKDRKEDAKGMEDEGQTKIKQRRSRTNFTLEQLNELERL 158
Query: 136 FDETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKCRKQENQMHKGVILGTANHLDACR 195
FDETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKCRKQENQ+HKGV++G A+ +ACR
Sbjct: 159 FDETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKCRKQENQLHKGVLIGAASQFEACR 218
Query: 196 VAPYVNMGALRMPFQ------------QVQAQLQLE-GVAHAHPHLHPHLAAHAPYLMFP 242
VAPYVN+GALRMPFQ QVQAQLQL+ VAHAH HLHPHLAAHAPY+MFP
Sbjct: 219 VAPYVNVGALRMPFQQDSHCNVTPLSFQVQAQLQLDSAVAHAHHHLHPHLAAHAPYMMFP 278
Query: 243 PPPFGLPIASL-AESASAAAVV--AAAAKSNSKNSSIADLRLKARKHAEALGL 292
PPFGLP+A+L A+SASAA+VV AAAAK+ SKNSSIADLRLKA+KHA ALGL
Sbjct: 279 APPFGLPLATLAADSASAASVVAAAAAAKTTSKNSSIADLRLKAKKHAAALGL 331
>gi|87044888 short stature homeobox 2 isoform b [Homo sapiens]
Length = 190
Score = 317 bits (811), Expect = 1e-86
Identities = 159/189 (84%), Positives = 177/189 (93%), Gaps = 4/189 (2%)
Query: 108 DEDGQTKLKQRRSRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQN 167
+++GQTK+KQRRSRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQN
Sbjct: 2 EDEGQTKIKQRRSRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQN 61
Query: 168 RRAKCRKQENQMHKGVILGTANHLDACRVAPYVNMGALRMPFQQVQAQLQLE-GVAHAHP 226
RRAKCRKQENQ+HKGV++G A+ +ACRVAPYVN+GALRMPFQQVQAQLQL+ VAHAH
Sbjct: 62 RRAKCRKQENQLHKGVLIGAASQFEACRVAPYVNVGALRMPFQQVQAQLQLDSAVAHAHH 121
Query: 227 HLHPHLAAHAPYLMFPPPPFGLPIASL-AESASAAAVV--AAAAKSNSKNSSIADLRLKA 283
HLHPHLAAHAPY+MFP PPFGLP+A+L A+SASAA+VV AAAAK+ SKNSSIADLRLKA
Sbjct: 122 HLHPHLAAHAPYMMFPAPPFGLPLATLAADSASAASVVAAAAAAKTTSKNSSIADLRLKA 181
Query: 284 RKHAEALGL 292
+KHA ALGL
Sbjct: 182 KKHAAALGL 190
>gi|126116581 retina and anterior neural fold homeobox [Homo
sapiens]
Length = 346
Score = 105 bits (261), Expect = 6e-23
Identities = 84/239 (35%), Positives = 112/239 (46%), Gaps = 32/239 (13%)
Query: 83 KEFGTARVAEGIYECKEKREDVKSEDEDGQTKLKQRRSRTNFTLEQLNELERLFDETHYP 142
KE G AR + G+ E SE+E Q K K RR+RT FT QL+ELER F+++HYP
Sbjct: 104 KEPGEARPSPGLPVGPATGEAKLSEEE--QPKKKHRRNRTTFTTYQLHELERAFEKSHYP 161
Query: 143 DAFMREELSQRLGLSEARVQVWFQNRRAKCRKQENQMHKGVILGTANHLDACRVAPYVNM 202
D + REEL+ ++ L E RVQVWFQNRRAK R+QE + L + L R P +
Sbjct: 162 DVYSREELAGKVNLPEVRVQVWFQNRRAKWRRQEKLEVSSMKLQDSPLLSFSRSPPSATL 221
Query: 203 GAL-------------RMPFQQVQAQLQLEGVAHAHPHL----HPHLAAHAPYLMFPPPP 245
L +P + G A A L P + A Y PPPP
Sbjct: 222 SPLGAGPGSGGGPAGGALPLESWLGPPLPGGGATALQSLPGFGPPAQSLPASYTPPPPPP 281
Query: 246 FGLPIASLAESASAAAVVAAA-------------AKSNSKNSSIADLRLKARKHAEALG 291
L L A + +++ +NSSIA LRLKA++H +A+G
Sbjct: 282 PFLNSPPLGPGLQPLAPPPPSYPCGPGFGDKFPLDEADPRNSSIAALRLKAKEHIQAIG 340
>gi|24497589 aristaless related homeobox [Homo sapiens]
Length = 562
Score = 105 bits (261), Expect = 6e-23
Identities = 85/241 (35%), Positives = 106/241 (43%), Gaps = 67/241 (27%)
Query: 106 SEDEDGQTKLKQRRSRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSEARVQVWF 165
S+ E+G K KQRR RT FT QL ELER F +THYPD F REEL+ RL L+EARVQVWF
Sbjct: 317 SDSEEGLLKRKQRRYRTTFTSYQLEELERAFQKTHYPDVFTREELAMRLDLTEARVQVWF 376
Query: 166 QNRRAKCRKQEN---QMHKGVILGTANHLDACRVAPYVNMGALRMPFQQVQAQLQLEGVA 222
QNRRAK RK+E Q H + ++PY++ PF L A
Sbjct: 377 QNRRAKWRKREKAGAQTHPPGLPFPGPLSATHPLSPYLDAS----PFPPHHPALDSAWTA 432
Query: 223 HAHPHLHPHLAAHAPYLMFPPPP--------------------------------FGLPI 250
A AA A + PPPP FG
Sbjct: 433 AA-------AAAAAAFPSLPPPPGSASLPPSGAPLGLSTFLGAAVFRHPAFISPAFGRLF 485
Query: 251 ASLAESASAAAVVA---------------------AAAKSNSKNSSIADLRLKARKHAEA 289
+++A SA+ A A A ++ + SSIA LRLKA++HA
Sbjct: 486 STMAPLTSASTAAALLRQPTPAVEGAVASGALADPATAAADRRASSIAALRLKAKEHAAQ 545
Query: 290 L 290
L
Sbjct: 546 L 546
>gi|122937484 dorsal root ganglia homeobox [Homo sapiens]
Length = 268
Score = 98.6 bits (244), Expect = 6e-21
Identities = 73/198 (36%), Positives = 103/198 (52%), Gaps = 18/198 (9%)
Query: 109 EDGQTKLKQRRSRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQNR 168
+DG + KQRR+RT FTL+QL LE +F +THYPD F REEL+ ++ L+EARVQVWFQNR
Sbjct: 30 DDGFLRRKQRRNRTTFTLQQLEALEAVFAQTHYPDVFTREELAMKINLTEARVQVWFQNR 89
Query: 169 RAKCRKQENQMHKGVILGTANHLDACRVAPYVNMGA------LRMPFQQVQAQLQL-EGV 221
RAK RK E G + P N+ + R + ++AQ L V
Sbjct: 90 RAKWRKTERGA-SDQEPGAKEPMAEVTPPPVRNINSPPPGDQARSKKEALEAQQSLGRTV 148
Query: 222 AHAHPHLHPHL-------AAHAPYLMFPPPPFGLPIAS--LAESASAAAVVAAAAKSNSK 272
A P L A +A L G P+ S + + + + +SN +
Sbjct: 149 GPAGPFFPSCLPGTLLNTATYAQALSHVASLKGGPLCSCCVPDPMGLSFLPTYGCQSN-R 207
Query: 273 NSSIADLRLKARKHAEAL 290
+S+A LR+KAR+H+EA+
Sbjct: 208 TASVATLRMKAREHSEAV 225
>gi|4505619 paired box 7 isoform 1 [Homo sapiens]
Length = 520
Score = 96.7 bits (239), Expect = 2e-20
Identities = 59/126 (46%), Positives = 74/126 (58%), Gaps = 10/126 (7%)
Query: 72 KDHVDNDKEKLKEFGTARVA---EGIYECKEKREDVKSEDE---DGQTKLKQRRSRTNFT 125
K +++ +K ++ G + +GI K R D S+ E D K KQRRSRT FT
Sbjct: 166 KKEEEDEADKKEDDGEKKAKHSIDGILGDKGNRLDEGSDVESEPDLPLKRKQRRSRTTFT 225
Query: 126 LEQLNELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKCRKQENQMHKGVIL 185
EQL ELE+ F+ THYPD + REEL+QR L+EARVQVWF NRRA+ RKQ L
Sbjct: 226 AEQLEELEKAFERTHYPDIYTREELAQRTKLTEARVQVWFSNRRARWRKQAGANQ----L 281
Query: 186 GTANHL 191
NHL
Sbjct: 282 AAFNHL 287
>gi|7524359 paired box 7 isoform 2 [Homo sapiens]
Length = 518
Score = 96.7 bits (239), Expect = 2e-20
Identities = 59/126 (46%), Positives = 74/126 (58%), Gaps = 10/126 (7%)
Query: 72 KDHVDNDKEKLKEFGTARVA---EGIYECKEKREDVKSEDE---DGQTKLKQRRSRTNFT 125
K +++ +K ++ G + +GI K R D S+ E D K KQRRSRT FT
Sbjct: 164 KKEEEDEADKKEDDGEKKAKHSIDGILGDKGNRLDEGSDVESEPDLPLKRKQRRSRTTFT 223
Query: 126 LEQLNELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKCRKQENQMHKGVIL 185
EQL ELE+ F+ THYPD + REEL+QR L+EARVQVWF NRRA+ RKQ L
Sbjct: 224 AEQLEELEKAFERTHYPDIYTREELAQRTKLTEARVQVWFSNRRARWRKQAGANQ----L 279
Query: 186 GTANHL 191
NHL
Sbjct: 280 AAFNHL 285
>gi|207029223 paired box 7 isoform 3 [Homo sapiens]
Length = 505
Score = 96.7 bits (239), Expect = 2e-20
Identities = 59/126 (46%), Positives = 74/126 (58%), Gaps = 10/126 (7%)
Query: 72 KDHVDNDKEKLKEFGTARVA---EGIYECKEKREDVKSEDE---DGQTKLKQRRSRTNFT 125
K +++ +K ++ G + +GI K R D S+ E D K KQRRSRT FT
Sbjct: 166 KKEEEDEADKKEDDGEKKAKHSIDGILGDKGNRLDEGSDVESEPDLPLKRKQRRSRTTFT 225
Query: 126 LEQLNELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKCRKQENQMHKGVIL 185
EQL ELE+ F+ THYPD + REEL+QR L+EARVQVWF NRRA+ RKQ L
Sbjct: 226 AEQLEELEKAFERTHYPDIYTREELAQRTKLTEARVQVWFSNRRARWRKQAGANQ----L 281
Query: 186 GTANHL 191
NHL
Sbjct: 282 AAFNHL 287
>gi|188219638 paired box 3 isoform PAX3i [Homo sapiens]
Length = 483
Score = 95.9 bits (237), Expect = 4e-20
Identities = 49/77 (63%), Positives = 57/77 (74%), Gaps = 1/77 (1%)
Query: 99 EKREDVKSEDEDGQTKLKQRRSRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSE 158
++ D+ SE D K KQRRSRT FT EQL ELER F+ THYPD + REEL+QR L+E
Sbjct: 201 DEGSDIDSEP-DLPLKRKQRRSRTTFTAEQLEELERAFERTHYPDIYTREELAQRAKLTE 259
Query: 159 ARVQVWFQNRRAKCRKQ 175
ARVQVWF NRRA+ RKQ
Sbjct: 260 ARVQVWFSNRRARWRKQ 276
>gi|31563348 paired box 3 isoform PAX3g [Homo sapiens]
Length = 403
Score = 95.9 bits (237), Expect = 4e-20
Identities = 49/77 (63%), Positives = 57/77 (74%), Gaps = 1/77 (1%)
Query: 99 EKREDVKSEDEDGQTKLKQRRSRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSE 158
++ D+ SE D K KQRRSRT FT EQL ELER F+ THYPD + REEL+QR L+E
Sbjct: 202 DEGSDIDSEP-DLPLKRKQRRSRTTFTAEQLEELERAFERTHYPDIYTREELAQRAKLTE 260
Query: 159 ARVQVWFQNRRAKCRKQ 175
ARVQVWF NRRA+ RKQ
Sbjct: 261 ARVQVWFSNRRARWRKQ 277
>gi|31563346 paired box 3 isoform PAX3h [Homo sapiens]
Length = 407
Score = 95.9 bits (237), Expect = 4e-20
Identities = 49/77 (63%), Positives = 57/77 (74%), Gaps = 1/77 (1%)
Query: 99 EKREDVKSEDEDGQTKLKQRRSRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSE 158
++ D+ SE D K KQRRSRT FT EQL ELER F+ THYPD + REEL+QR L+E
Sbjct: 202 DEGSDIDSEP-DLPLKRKQRRSRTTFTAEQLEELERAFERTHYPDIYTREELAQRAKLTE 260
Query: 159 ARVQVWFQNRRAKCRKQ 175
ARVQVWF NRRA+ RKQ
Sbjct: 261 ARVQVWFSNRRARWRKQ 277
>gi|31563344 paired box 3 isoform PAX3e [Homo sapiens]
Length = 505
Score = 95.9 bits (237), Expect = 4e-20
Identities = 49/77 (63%), Positives = 57/77 (74%), Gaps = 1/77 (1%)
Query: 99 EKREDVKSEDEDGQTKLKQRRSRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSE 158
++ D+ SE D K KQRRSRT FT EQL ELER F+ THYPD + REEL+QR L+E
Sbjct: 202 DEGSDIDSEP-DLPLKRKQRRSRTTFTAEQLEELERAFERTHYPDIYTREELAQRAKLTE 260
Query: 159 ARVQVWFQNRRAKCRKQ 175
ARVQVWF NRRA+ RKQ
Sbjct: 261 ARVQVWFSNRRARWRKQ 277
>gi|31563342 paired box 3 isoform PAX3d [Homo sapiens]
Length = 484
Score = 95.9 bits (237), Expect = 4e-20
Identities = 49/77 (63%), Positives = 57/77 (74%), Gaps = 1/77 (1%)
Query: 99 EKREDVKSEDEDGQTKLKQRRSRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSE 158
++ D+ SE D K KQRRSRT FT EQL ELER F+ THYPD + REEL+QR L+E
Sbjct: 202 DEGSDIDSEP-DLPLKRKQRRSRTTFTAEQLEELERAFERTHYPDIYTREELAQRAKLTE 260
Query: 159 ARVQVWFQNRRAKCRKQ 175
ARVQVWF NRRA+ RKQ
Sbjct: 261 ARVQVWFSNRRARWRKQ 277
>gi|31563340 paired box 3 isoform PAX3 [Homo sapiens]
Length = 479
Score = 95.9 bits (237), Expect = 4e-20
Identities = 49/77 (63%), Positives = 57/77 (74%), Gaps = 1/77 (1%)
Query: 99 EKREDVKSEDEDGQTKLKQRRSRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSE 158
++ D+ SE D K KQRRSRT FT EQL ELER F+ THYPD + REEL+QR L+E
Sbjct: 202 DEGSDIDSEP-DLPLKRKQRRSRTTFTAEQLEELERAFERTHYPDIYTREELAQRAKLTE 260
Query: 159 ARVQVWFQNRRAKCRKQ 175
ARVQVWF NRRA+ RKQ
Sbjct: 261 ARVQVWFSNRRARWRKQ 277
>gi|7706659 paired related homeobox 2 [Homo sapiens]
Length = 253
Score = 95.5 bits (236), Expect = 5e-20
Identities = 45/66 (68%), Positives = 53/66 (80%)
Query: 114 KLKQRRSRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKCR 173
K KQRR+RT F QL LER+F+ THYPDAF+REEL++R+ LSEARVQVWFQNRRAK R
Sbjct: 101 KKKQRRNRTTFNSSQLQALERVFERTHYPDAFVREELARRVNLSEARVQVWFQNRRAKFR 160
Query: 174 KQENQM 179
+ E M
Sbjct: 161 RNERAM 166
>gi|4826912 paired-like homeodomain 3 [Homo sapiens]
Length = 302
Score = 95.1 bits (235), Expect = 6e-20
Identities = 95/307 (30%), Positives = 127/307 (41%), Gaps = 90/307 (29%)
Query: 39 LESGLARSRELGTSDSSLQDITEGGGHCPVHLFKDHVDNDKEKLKEFGTARVAEGIYECK 98
+E GL E + SL D P H K +D EK +A + G
Sbjct: 1 MEFGLLSEAEARSPALSLSDAGTPHPQLPEHGCKGQEHSDSEK----ASASLPGG----- 51
Query: 99 EKREDVKSEDEDGQTKLKQRRSRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSE 158
EDG K KQRR RT+FT +QL ELE F YPD REE++ L+E
Sbjct: 52 --------SPEDGSLKKKQRRQRTHFTSQQLQELEATFQRNRYPDMSTREEIAVWTNLTE 103
Query: 159 ARVQVWFQNRRAKCRKQENQMHKGVILGTANHLDACRVAPYVNMGALRMPFQQVQAQLQL 218
ARV+VWF+NRRAK RK+E + + C+ + +G L P+++V
Sbjct: 104 ARVRVWFKNRRAKWRKRER----------SQQAELCKGSFAAPLGGLVPPYEEV-----Y 148
Query: 219 EGVAHAH---PHLHPHLAAH--------------APYLMFPPP----------------- 244
G ++ + L P LAA A +F PP
Sbjct: 149 PGYSYGNWPPKALAPPLAAKTFPFAFNSVNVGPLASQPVFSPPSSIAASMVPSAAAAPGT 208
Query: 245 -------------PFGLPIASLAES------ASAAAVVAAAAKS-----NSKNSSIADLR 280
P GL A+++ ASAAA AAAA S + NSS+A LR
Sbjct: 209 VPGPGALQGLGGGPPGLAPAAVSSGAVSCPYASAAAAAAAAASSPYVYRDPCNSSLASLR 268
Query: 281 LKARKHA 287
LKA++HA
Sbjct: 269 LKAKQHA 275
>gi|5902024 paired mesoderm homeobox 1 isoform pmx-1a [Homo sapiens]
Length = 217
Score = 95.1 bits (235), Expect = 6e-20
Identities = 59/153 (38%), Positives = 87/153 (56%), Gaps = 12/153 (7%)
Query: 27 GGKKDSITYREVLESGLARSRELGTSDSSLQDITEGGGHCPVHLFKDHVDNDKEKLKEFG 86
GG+ DS + L++ + S S L D+ E G ++ + + L+ G
Sbjct: 16 GGRLDSPGNLDTLQA------KKNFSVSHLLDLEEAGDMVAAQADENVGEAGRSLLESPG 69
Query: 87 TARVAEGIYECKEKREDVKSEDEDGQTKLKQRRSRTNFTLEQLNELERLFDETHYPDAFM 146
+ G ++ + + SE++ K KQRR+RT F QL LER+F+ THYPDAF+
Sbjct: 70 ---LTSGSDTPQQDNDQLNSEEKK---KRKQRRNRTTFNSSQLQALERVFERTHYPDAFV 123
Query: 147 REELSQRLGLSEARVQVWFQNRRAKCRKQENQM 179
RE+L++R+ L+EARVQVWFQNRRAK R+ E M
Sbjct: 124 REDLARRVNLTEARVQVWFQNRRAKFRRNERAM 156
>gi|12707577 paired mesoderm homeobox 1 isoform pmx-1b [Homo
sapiens]
Length = 245
Score = 95.1 bits (235), Expect = 6e-20
Identities = 59/153 (38%), Positives = 87/153 (56%), Gaps = 12/153 (7%)
Query: 27 GGKKDSITYREVLESGLARSRELGTSDSSLQDITEGGGHCPVHLFKDHVDNDKEKLKEFG 86
GG+ DS + L++ + S S L D+ E G ++ + + L+ G
Sbjct: 16 GGRLDSPGNLDTLQA------KKNFSVSHLLDLEEAGDMVAAQADENVGEAGRSLLESPG 69
Query: 87 TARVAEGIYECKEKREDVKSEDEDGQTKLKQRRSRTNFTLEQLNELERLFDETHYPDAFM 146
+ G ++ + + SE++ K KQRR+RT F QL LER+F+ THYPDAF+
Sbjct: 70 ---LTSGSDTPQQDNDQLNSEEKK---KRKQRRNRTTFNSSQLQALERVFERTHYPDAFV 123
Query: 147 REELSQRLGLSEARVQVWFQNRRAKCRKQENQM 179
RE+L++R+ L+EARVQVWFQNRRAK R+ E M
Sbjct: 124 REDLARRVNLTEARVQVWFQNRRAKFRRNERAM 156
>gi|239754062 PREDICTED: orthopedia homeobox [Homo sapiens]
Length = 325
Score = 92.8 bits (229), Expect = 3e-19
Identities = 44/65 (67%), Positives = 54/65 (83%)
Query: 112 QTKLKQRRSRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQNRRAK 171
Q + KQ+R RT FT QLNELER F +THYPD FMREEL+ R+GL+E+RVQVWFQNRRAK
Sbjct: 99 QGQQKQKRHRTRFTPAQLNELERSFAKTHYPDIFMREELALRIGLTESRVQVWFQNRRAK 158
Query: 172 CRKQE 176
+K++
Sbjct: 159 WKKRK 163
>gi|12707580 paired-like homeobox 2b [Homo sapiens]
Length = 314
Score = 92.8 bits (229), Expect = 3e-19
Identities = 45/63 (71%), Positives = 51/63 (80%)
Query: 114 KLKQRRSRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKCR 173
K KQRR RT FT QL ELER+F ETHYPD + REEL+ ++ L+EARVQVWFQNRRAK R
Sbjct: 95 KRKQRRIRTTFTSAQLKELERVFAETHYPDIYTREELALKIDLTEARVQVWFQNRRAKFR 154
Query: 174 KQE 176
KQE
Sbjct: 155 KQE 157
>gi|46249382 paired-like homeobox 2a [Homo sapiens]
Length = 284
Score = 92.8 bits (229), Expect = 3e-19
Identities = 45/63 (71%), Positives = 51/63 (80%)
Query: 114 KLKQRRSRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKCR 173
K KQRR RT FT QL ELER+F ETHYPD + REEL+ ++ L+EARVQVWFQNRRAK R
Sbjct: 87 KRKQRRIRTTFTSAQLKELERVFAETHYPDIYTREELALKIDLTEARVQVWFQNRRAKFR 146
Query: 174 KQE 176
KQE
Sbjct: 147 KQE 149
>gi|14149760 orthopedia homeobox [Homo sapiens]
Length = 325
Score = 92.8 bits (229), Expect = 3e-19
Identities = 44/65 (67%), Positives = 54/65 (83%)
Query: 112 QTKLKQRRSRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQNRRAK 171
Q + KQ+R RT FT QLNELER F +THYPD FMREEL+ R+GL+E+RVQVWFQNRRAK
Sbjct: 99 QGQQKQKRHRTRFTPAQLNELERSFAKTHYPDIFMREELALRIGLTESRVQVWFQNRRAK 158
Query: 172 CRKQE 176
+K++
Sbjct: 159 WKKRK 163
>gi|14249388 retina and anterior neural fold homeobox 2 [Homo
sapiens]
Length = 184
Score = 92.4 bits (228), Expect = 4e-19
Identities = 70/177 (39%), Positives = 89/177 (50%), Gaps = 23/177 (12%)
Query: 114 KLKQRRSRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKCR 173
K K RR+RT FT QL++LER F+ +HYPD + REEL+ ++ L E RVQVWFQNRRAK R
Sbjct: 24 KKKHRRNRTTFTTYQLHQLERAFEASHYPDVYSREELAAKVHLPEVRVQVWFQNRRAKWR 83
Query: 174 KQENQMHKGVILGTANHLDACRVAPYVNMGALRMPFQQVQAQLQLEGVAHAHPHLHPHLA 233
+QE ++ G A L P+ A+ +P LE P P L
Sbjct: 84 RQE-RLESGSGAVAAPRLPEAPALPFARPPAMSLP---------LEPWLGPGPPAVPGL- 132
Query: 234 AHAPYLMFPPPPFGLPIASLAESASAAAVVAAAAKSNSKNSSIADLRLKARKHAEAL 290
P L+ P P GL AS A A A A LRL A++HA+AL
Sbjct: 133 ---PRLLGPGP--GLQ-ASFGPHAFAPTFADGFALEE------ASLRLLAKEHAQAL 177
>gi|122937321 UNC homeobox [Homo sapiens]
Length = 531
Score = 91.7 bits (226), Expect = 7e-19
Identities = 44/62 (70%), Positives = 52/62 (83%)
Query: 116 KQRRSRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKCRKQ 175
K+RR+RTNFT QL ELE+ F+E+HYPD FMRE L+ RL L E+RVQVWFQNRRAK RK+
Sbjct: 104 KRRRTRTNFTGWQLEELEKAFNESHYPDVFMREALALRLDLVESRVQVWFQNRRAKWRKK 163
Query: 176 EN 177
EN
Sbjct: 164 EN 165
>gi|55743092 aristaless-like homeobox 4 [Homo sapiens]
Length = 411
Score = 90.5 bits (223), Expect = 2e-18
Identities = 75/217 (34%), Positives = 101/217 (46%), Gaps = 40/217 (18%)
Query: 102 EDVKSEDEDGQTKLKQRRSRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSEARV 161
E SE G K+RR+RT FT QL ELE++F +THYPD + RE+L+ R L+EARV
Sbjct: 203 EKADSESNKG----KKRRNRTTFTSYQLEELEKVFQKTHYPDVYAREQLAMRTDLTEARV 258
Query: 162 QVWFQNRRAKCRKQENQMHKGVILGTANHLDACRVAPYVNMGALRMPFQQVQAQLQLEGV 221
QVWFQNRRAK RK+E G + H P + + Q+Q L
Sbjct: 259 QVWFQNRRAKWRKRE---RFGQMQQVRTHFSTAYELPLLTRAE---NYAQIQNPSWLGNN 312
Query: 222 AHAHP------HLHPHLAAHAPYLMFPPPPFGLPIASLAESASAA----------AVVAA 265
A P P A +P+ PP G + S S A ++ A
Sbjct: 313 GAASPVPACVVPCDPVPACMSPHA--HPPGSGASSVTDFLSVSGAGSHVGQTHMGSLFGA 370
Query: 266 AAKS------------NSKNSSIADLRLKARKHAEAL 290
A+ S + K SSIA LR+KA++H+ A+
Sbjct: 371 ASLSPGLNGYELNGEPDRKTSSIAALRMKAKEHSAAI 407
>gi|27436933 orthodenticle homeobox 2 isoform b [Homo sapiens]
Length = 289
Score = 90.1 bits (222), Expect = 2e-18
Identities = 42/70 (60%), Positives = 52/70 (74%)
Query: 113 TKLKQRRSRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKC 172
T KQRR RT FT QL+ LE LF +T YPD FMREE++ ++ L E+RVQVWF+NRRAKC
Sbjct: 34 TPRKQRRERTTFTRAQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKC 93
Query: 173 RKQENQMHKG 182
R+Q+ Q G
Sbjct: 94 RQQQQQQQNG 103
>gi|11119420 orthodenticle homeobox 2 isoform a [Homo sapiens]
Length = 297
Score = 90.1 bits (222), Expect = 2e-18
Identities = 42/70 (60%), Positives = 52/70 (74%)
Query: 113 TKLKQRRSRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSEARVQVWFQNRRAKC 172
T KQRR RT FT QL+ LE LF +T YPD FMREE++ ++ L E+RVQVWF+NRRAKC
Sbjct: 42 TPRKQRRERTTFTRAQLDVLEALFAKTRYPDIFMREEVALKINLPESRVQVWFKNRRAKC 101
Query: 173 RKQENQMHKG 182
R+Q+ Q G
Sbjct: 102 RQQQQQQQNG 111
>gi|27436936 diencephalon/mesencephalon homeobox 1 isoform a [Homo
sapiens]
Length = 377
Score = 88.6 bits (218), Expect = 6e-18
Identities = 44/83 (53%), Positives = 54/83 (65%)
Query: 99 EKREDVKSEDEDGQTKLKQRRSRTNFTLEQLNELERLFDETHYPDAFMREELSQRLGLSE 158
E+ D+ E G KQRRSRT FT +QL LE+ F +THYPD MRE L+ L E
Sbjct: 48 ERLADIILEARYGSQHRKQRRSRTAFTAQQLEALEKTFQKTHYPDVVMRERLAMCTNLPE 107
Query: 159 ARVQVWFQNRRAKCRKQENQMHK 181
ARVQVWF+NRRAK RK++ + K
Sbjct: 108 ARVQVWFKNRRAKFRKKQRSLQK 130
Score = 38.1 bits (87), Expect = 0.009
Identities = 30/79 (37%), Positives = 39/79 (49%), Gaps = 19/79 (24%)
Query: 233 AAHAPYLMFPPPPFG-LPIASLAESASAAA------------------VVAAAAKSNSKN 273
AA PYL P G L S +S SAAA + A+A NSK
Sbjct: 294 AAAVPYLGVNMAPLGSLHCQSYYQSLSAAAAAHQGVWGSPLLPAPPAGLAPASATLNSKT 353
Query: 274 SSIADLRLKARKHAEALGL 292
+SI +LRL+A++HA +LGL
Sbjct: 354 TSIENLRLRAKQHAASLGL 372
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.131 0.377
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,420,904
Number of Sequences: 37866
Number of extensions: 530382
Number of successful extensions: 6807
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 338
Number of HSP's successfully gapped in prelim test: 101
Number of HSP's that attempted gapping in prelim test: 5483
Number of HSP's gapped (non-prelim): 1240
length of query: 292
length of database: 18,247,518
effective HSP length: 101
effective length of query: 191
effective length of database: 14,423,052
effective search space: 2754802932
effective search space used: 2754802932
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.