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Search of human proteins with 4506923
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4506923 SH2 domain protein 1A isoform 1 [Homo sapiens]
(128 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4506923 SH2 domain protein 1A isoform 1 [Homo sapiens] 263 3e-71
gi|169234945 SH2 domain protein 1A isoform 2 [Homo sapiens] 251 8e-68
gi|54792745 SH2 domain containing 1B [Homo sapiens] 106 4e-24
gi|40254823 SH2 containing inositol phosphatase isoform b [Homo ... 92 8e-20
gi|64085167 SH2 containing inositol phosphatase isoform a [Homo ... 92 8e-20
gi|222136583 inositol polyphosphate phosphatase-like 1 [Homo sap... 86 6e-18
gi|62362414 c-abl oncogene 1, receptor tyrosine kinase isoform a... 60 6e-10
gi|62362412 c-abl oncogene 1, receptor tyrosine kinase isoform b... 60 6e-10
gi|153266778 arg tyrosine kinase isoform c [Homo sapiens] 55 1e-08
gi|6382062 arg tyrosine kinase isoform b [Homo sapiens] 55 1e-08
gi|209862778 arg tyrosine kinase isoform e [Homo sapiens] 55 1e-08
gi|209862772 arg tyrosine kinase isoform d [Homo sapiens] 55 1e-08
gi|153266757 arg tyrosine kinase isoform a [Homo sapiens] 55 1e-08
gi|158631203 dual adaptor of phosphotyrosine and 3-phosphoinosit... 50 5e-07
gi|205277435 spleen tyrosine kinase isoform 2 [Homo sapiens] 49 1e-06
gi|21361553 spleen tyrosine kinase isoform 1 [Homo sapiens] 49 1e-06
gi|4503787 fyn-related kinase [Homo sapiens] 46 9e-06
gi|187475373 c-src tyrosine kinase [Homo sapiens] 45 2e-05
gi|4758078 c-src tyrosine kinase [Homo sapiens] 45 2e-05
gi|15718680 IL2-inducible T-cell kinase [Homo sapiens] 44 3e-05
gi|48762697 growth factor receptor-bound protein 10 isoform c [H... 44 4e-05
gi|48762695 growth factor receptor-bound protein 10 isoform c [H... 44 4e-05
gi|48762693 growth factor receptor-bound protein 10 isoform b [H... 44 4e-05
gi|48762679 growth factor receptor-bound protein 10 isoform a [H... 44 4e-05
gi|5729856 GRB2-related adaptor protein [Homo sapiens] 43 8e-05
gi|4757980 beta chimerin isoform 2 [Homo sapiens] 42 1e-04
gi|4502813 chimerin (chimaerin) 1 isoform a [Homo sapiens] 42 1e-04
gi|209364623 chimerin (chimaerin) 1 isoform b [Homo sapiens] 42 1e-04
gi|4506431 RAS p21 protein activator 1 isoform 1 [Homo sapiens] 41 2e-04
gi|12545406 RAS p21 protein activator 1 isoform 2 [Homo sapiens] 41 2e-04
>gi|4506923 SH2 domain protein 1A isoform 1 [Homo sapiens]
Length = 128
Score = 263 bits (672), Expect = 3e-71
Identities = 128/128 (100%), Positives = 128/128 (100%)
Query: 1 MDAVAVYHGKISRETGEKLLLATGLDGSYLLRDSESVPGVYCLCVLYHGYIYTYRVSQTE 60
MDAVAVYHGKISRETGEKLLLATGLDGSYLLRDSESVPGVYCLCVLYHGYIYTYRVSQTE
Sbjct: 1 MDAVAVYHGKISRETGEKLLLATGLDGSYLLRDSESVPGVYCLCVLYHGYIYTYRVSQTE 60
Query: 61 TGSWSAETAPGVHKRYFRKIKNLISAFQKPDQGIVIPLQYPVEKKSSARSTQGTTGIRED 120
TGSWSAETAPGVHKRYFRKIKNLISAFQKPDQGIVIPLQYPVEKKSSARSTQGTTGIRED
Sbjct: 61 TGSWSAETAPGVHKRYFRKIKNLISAFQKPDQGIVIPLQYPVEKKSSARSTQGTTGIRED 120
Query: 121 PDVCLKAP 128
PDVCLKAP
Sbjct: 121 PDVCLKAP 128
>gi|169234945 SH2 domain protein 1A isoform 2 [Homo sapiens]
Length = 125
Score = 251 bits (642), Expect = 8e-68
Identities = 125/128 (97%), Positives = 125/128 (97%), Gaps = 3/128 (2%)
Query: 1 MDAVAVYHGKISRETGEKLLLATGLDGSYLLRDSESVPGVYCLCVLYHGYIYTYRVSQTE 60
MDAVAVYHGKISRETGEKLLLATGLDGSYLLRDSESVPGVYCLCVLYHGYIYTYRVSQTE
Sbjct: 1 MDAVAVYHGKISRETGEKLLLATGLDGSYLLRDSESVPGVYCLCVLYHGYIYTYRVSQTE 60
Query: 61 TGSWSAETAPGVHKRYFRKIKNLISAFQKPDQGIVIPLQYPVEKKSSARSTQGTTGIRED 120
TGSWSAETAPGVHKRYFRKIKNLISAFQKPDQGIVIPLQYPVEKKSSARSTQ GIRED
Sbjct: 61 TGSWSAETAPGVHKRYFRKIKNLISAFQKPDQGIVIPLQYPVEKKSSARSTQ---GIRED 117
Query: 121 PDVCLKAP 128
PDVCLKAP
Sbjct: 118 PDVCLKAP 125
>gi|54792745 SH2 domain containing 1B [Homo sapiens]
Length = 132
Score = 106 bits (265), Expect = 4e-24
Identities = 48/107 (44%), Positives = 75/107 (70%)
Query: 7 YHGKISRETGEKLLLATGLDGSYLLRDSESVPGVYCLCVLYHGYIYTYRVSQTETGSWSA 66
YHG+++++ E LLL G+DG++LLRDSES+PGV CLCV + +YTYR+ + + G +
Sbjct: 6 YHGRLTKQDCETLLLKEGVDGNFLLRDSESIPGVLCLCVSFKNIVYTYRIFREKHGYYRI 65
Query: 67 ETAPGVHKRYFRKIKNLISAFQKPDQGIVIPLQYPVEKKSSARSTQG 113
+TA G K+ F +K LIS F+KP+QG+V+ L P+++ S + +G
Sbjct: 66 QTAEGSPKQVFPSLKELISKFEKPNQGMVVHLLKPIKRTSPSLRWRG 112
>gi|40254823 SH2 containing inositol phosphatase isoform b [Homo
sapiens]
Length = 1188
Score = 92.4 bits (228), Expect = 8e-20
Identities = 43/95 (45%), Positives = 60/95 (63%)
Query: 8 HGKISRETGEKLLLATGLDGSYLLRDSESVPGVYCLCVLYHGYIYTYRVSQTETGSWSAE 67
HG I+R E+LL TG DGS+L+R SES+ Y LCVLY +YTYR+ E ++ +
Sbjct: 7 HGNITRSKAEELLSRTGKDGSFLVRASESISRAYALCVLYRNCVYTYRILPNEDDKFTVQ 66
Query: 68 TAPGVHKRYFRKIKNLISAFQKPDQGIVIPLQYPV 102
+ GV R+F K+ LI ++K + G+V LQYPV
Sbjct: 67 ASEGVSMRFFTKLDQLIEFYKKENMGLVTHLQYPV 101
>gi|64085167 SH2 containing inositol phosphatase isoform a [Homo
sapiens]
Length = 1189
Score = 92.4 bits (228), Expect = 8e-20
Identities = 43/95 (45%), Positives = 60/95 (63%)
Query: 8 HGKISRETGEKLLLATGLDGSYLLRDSESVPGVYCLCVLYHGYIYTYRVSQTETGSWSAE 67
HG I+R E+LL TG DGS+L+R SES+ Y LCVLY +YTYR+ E ++ +
Sbjct: 7 HGNITRSKAEELLSRTGKDGSFLVRASESISRAYALCVLYRNCVYTYRILPNEDDKFTVQ 66
Query: 68 TAPGVHKRYFRKIKNLISAFQKPDQGIVIPLQYPV 102
+ GV R+F K+ LI ++K + G+V LQYPV
Sbjct: 67 ASEGVSMRFFTKLDQLIEFYKKENMGLVTHLQYPV 101
>gi|222136583 inositol polyphosphate phosphatase-like 1 [Homo
sapiens]
Length = 1258
Score = 86.3 bits (212), Expect = 6e-18
Identities = 42/97 (43%), Positives = 60/97 (61%)
Query: 7 YHGKISRETGEKLLLATGLDGSYLLRDSESVPGVYCLCVLYHGYIYTYRVSQTETGSWSA 66
YH +SR E+LL G DGS+L+RDSESV G + LCVLY +++TYR+ +
Sbjct: 22 YHRDLSRAAAEELLARAGRDGSFLVRDSESVAGAFALCVLYQKHVHTYRILPDGEDFLAV 81
Query: 67 ETAPGVHKRYFRKIKNLISAFQKPDQGIVIPLQYPVE 103
+T+ GV R F+ + LI + +P+QG+V L PVE
Sbjct: 82 QTSQGVPVRRFQTLGELIGLYAQPNQGLVCALLLPVE 118
>gi|62362414 c-abl oncogene 1, receptor tyrosine kinase isoform a
[Homo sapiens]
Length = 1130
Score = 59.7 bits (143), Expect = 6e-10
Identities = 31/100 (31%), Positives = 52/100 (52%), Gaps = 6/100 (6%)
Query: 7 YHGKISRETGEKLLLATGLDGSYLLRDSESVPGVYCLCVLYHGYIYTYRVSQTETGSWSA 66
YHG +SR E LL++G++GS+L+R+SES PG + + Y G +Y YR++ G
Sbjct: 128 YHGPVSRNAAE-YLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTASDGKLYV 186
Query: 67 ETAPGVHKRYFRKIKNLISAFQKPDQGIVIPLQYPVEKKS 106
+ + F + L+ G++ L YP K++
Sbjct: 187 SS-----ESRFNTLAELVHHHSTVADGLITTLHYPAPKRN 221
>gi|62362412 c-abl oncogene 1, receptor tyrosine kinase isoform b
[Homo sapiens]
Length = 1149
Score = 59.7 bits (143), Expect = 6e-10
Identities = 31/100 (31%), Positives = 52/100 (52%), Gaps = 6/100 (6%)
Query: 7 YHGKISRETGEKLLLATGLDGSYLLRDSESVPGVYCLCVLYHGYIYTYRVSQTETGSWSA 66
YHG +SR E LL++G++GS+L+R+SES PG + + Y G +Y YR++ G
Sbjct: 147 YHGPVSRNAAE-YLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTASDGKLYV 205
Query: 67 ETAPGVHKRYFRKIKNLISAFQKPDQGIVIPLQYPVEKKS 106
+ + F + L+ G++ L YP K++
Sbjct: 206 SS-----ESRFNTLAELVHHHSTVADGLITTLHYPAPKRN 240
>gi|153266778 arg tyrosine kinase isoform c [Homo sapiens]
Length = 1167
Score = 55.5 bits (132), Expect = 1e-08
Identities = 32/98 (32%), Positives = 49/98 (50%), Gaps = 6/98 (6%)
Query: 7 YHGKISRETGEKLLLATGLDGSYLLRDSESVPGVYCLCVLYHGYIYTYRVSQTETGSWSA 66
YHG +SR E LL++ ++GS+L+R+SES PG + + Y G +Y YR++ T G
Sbjct: 159 YHGPVSRSAAE-YLLSSLINGSFLVRESESSPGQLSISLRYEGRVYHYRINTTADGKVYV 217
Query: 67 ETAPGVHKRYFRKIKNLISAFQKPDQGIVIPLQYPVEK 104
+ F + L+ G+V L YP K
Sbjct: 218 TA-----ESRFSTLAELVHHHSTVADGLVTTLHYPAPK 250
>gi|6382062 arg tyrosine kinase isoform b [Homo sapiens]
Length = 1182
Score = 55.5 bits (132), Expect = 1e-08
Identities = 32/98 (32%), Positives = 49/98 (50%), Gaps = 6/98 (6%)
Query: 7 YHGKISRETGEKLLLATGLDGSYLLRDSESVPGVYCLCVLYHGYIYTYRVSQTETGSWSA 66
YHG +SR E LL++ ++GS+L+R+SES PG + + Y G +Y YR++ T G
Sbjct: 174 YHGPVSRSAAE-YLLSSLINGSFLVRESESSPGQLSISLRYEGRVYHYRINTTADGKVYV 232
Query: 67 ETAPGVHKRYFRKIKNLISAFQKPDQGIVIPLQYPVEK 104
+ F + L+ G+V L YP K
Sbjct: 233 TA-----ESRFSTLAELVHHHSTVADGLVTTLHYPAPK 265
>gi|209862778 arg tyrosine kinase isoform e [Homo sapiens]
Length = 542
Score = 55.5 bits (132), Expect = 1e-08
Identities = 32/98 (32%), Positives = 49/98 (50%), Gaps = 6/98 (6%)
Query: 7 YHGKISRETGEKLLLATGLDGSYLLRDSESVPGVYCLCVLYHGYIYTYRVSQTETGSWSA 66
YHG +SR E LL++ ++GS+L+R+SES PG + + Y G +Y YR++ T G
Sbjct: 153 YHGPVSRSAAE-YLLSSLINGSFLVRESESSPGQLSISLRYEGRVYHYRINTTADGKVYV 211
Query: 67 ETAPGVHKRYFRKIKNLISAFQKPDQGIVIPLQYPVEK 104
+ F + L+ G+V L YP K
Sbjct: 212 TA-----ESRFSTLAELVHHHSTVADGLVTTLHYPAPK 244
>gi|209862772 arg tyrosine kinase isoform d [Homo sapiens]
Length = 1064
Score = 55.5 bits (132), Expect = 1e-08
Identities = 32/98 (32%), Positives = 49/98 (50%), Gaps = 6/98 (6%)
Query: 7 YHGKISRETGEKLLLATGLDGSYLLRDSESVPGVYCLCVLYHGYIYTYRVSQTETGSWSA 66
YHG +SR E LL++ ++GS+L+R+SES PG + + Y G +Y YR++ T G
Sbjct: 159 YHGPVSRSAAE-YLLSSLINGSFLVRESESSPGQLSISLRYEGRVYHYRINTTADGKVYV 217
Query: 67 ETAPGVHKRYFRKIKNLISAFQKPDQGIVIPLQYPVEK 104
+ F + L+ G+V L YP K
Sbjct: 218 TA-----ESRFSTLAELVHHHSTVADGLVTTLHYPAPK 250
>gi|153266757 arg tyrosine kinase isoform a [Homo sapiens]
Length = 1146
Score = 55.5 bits (132), Expect = 1e-08
Identities = 32/98 (32%), Positives = 49/98 (50%), Gaps = 6/98 (6%)
Query: 7 YHGKISRETGEKLLLATGLDGSYLLRDSESVPGVYCLCVLYHGYIYTYRVSQTETGSWSA 66
YHG +SR E LL++ ++GS+L+R+SES PG + + Y G +Y YR++ T G
Sbjct: 138 YHGPVSRSAAE-YLLSSLINGSFLVRESESSPGQLSISLRYEGRVYHYRINTTADGKVYV 196
Query: 67 ETAPGVHKRYFRKIKNLISAFQKPDQGIVIPLQYPVEK 104
+ F + L+ G+V L YP K
Sbjct: 197 TA-----ESRFSTLAELVHHHSTVADGLVTTLHYPAPK 229
>gi|158631203 dual adaptor of phosphotyrosine and
3-phosphoinositides [Homo sapiens]
Length = 280
Score = 50.1 bits (118), Expect = 5e-07
Identities = 24/53 (45%), Positives = 30/53 (56%)
Query: 7 YHGKISRETGEKLLLATGLDGSYLLRDSESVPGVYCLCVLYHGYIYTYRVSQT 59
YHG ++R E LLL+ G DGSYLLRDS G+Y L V + + V T
Sbjct: 36 YHGNLTRHAAEALLLSNGCDGSYLLRDSNETTGLYSLSVRAKDSVKHFHVEYT 88
>gi|205277435 spleen tyrosine kinase isoform 2 [Homo sapiens]
Length = 612
Score = 48.9 bits (115), Expect = 1e-06
Identities = 29/99 (29%), Positives = 52/99 (52%), Gaps = 7/99 (7%)
Query: 7 YHGKISRETGEKL-LLATGLDGSYLLRDSESVPGVYCLCVLYHGYIYTYRVSQTETGSWS 65
+HGKISRE E++ L+ + +G +L+R ++ G Y LC+L+ G + YR+ + +TG S
Sbjct: 169 FHGKISREESEQIVLIGSKTNGKFLIRARDN-NGSYALCLLHEGKVLHYRIDKDKTGKLS 227
Query: 66 AETAPGVHKRYFRKIKNLISAFQKPDQGIVIPLQYPVEK 104
+ F + L+ + G++ L P +K
Sbjct: 228 IPEG-----KKFDTLWQLVEHYSYKADGLLRVLTVPCQK 261
Score = 34.3 bits (77), Expect = 0.027
Identities = 19/60 (31%), Positives = 32/60 (53%), Gaps = 1/60 (1%)
Query: 7 YHGKISRETGEKLLLATGL-DGSYLLRDSESVPGVYCLCVLYHGYIYTYRVSQTETGSWS 65
+ G I+RE E L+ G+ DG YLLR S + G + L V + + Y + + G+++
Sbjct: 16 FFGNITREEAEDYLVQGGMSDGLYLLRQSRNYLGGFALSVAHGRKAHHYTIERELNGTYA 75
>gi|21361553 spleen tyrosine kinase isoform 1 [Homo sapiens]
Length = 635
Score = 48.9 bits (115), Expect = 1e-06
Identities = 29/99 (29%), Positives = 52/99 (52%), Gaps = 7/99 (7%)
Query: 7 YHGKISRETGEKL-LLATGLDGSYLLRDSESVPGVYCLCVLYHGYIYTYRVSQTETGSWS 65
+HGKISRE E++ L+ + +G +L+R ++ G Y LC+L+ G + YR+ + +TG S
Sbjct: 169 FHGKISREESEQIVLIGSKTNGKFLIRARDN-NGSYALCLLHEGKVLHYRIDKDKTGKLS 227
Query: 66 AETAPGVHKRYFRKIKNLISAFQKPDQGIVIPLQYPVEK 104
+ F + L+ + G++ L P +K
Sbjct: 228 IPEG-----KKFDTLWQLVEHYSYKADGLLRVLTVPCQK 261
Score = 34.3 bits (77), Expect = 0.027
Identities = 19/60 (31%), Positives = 32/60 (53%), Gaps = 1/60 (1%)
Query: 7 YHGKISRETGEKLLLATGL-DGSYLLRDSESVPGVYCLCVLYHGYIYTYRVSQTETGSWS 65
+ G I+RE E L+ G+ DG YLLR S + G + L V + + Y + + G+++
Sbjct: 16 FFGNITREEAEDYLVQGGMSDGLYLLRQSRNYLGGFALSVAHGRKAHHYTIERELNGTYA 75
>gi|4503787 fyn-related kinase [Homo sapiens]
Length = 505
Score = 45.8 bits (107), Expect = 9e-06
Identities = 29/99 (29%), Positives = 46/99 (46%), Gaps = 6/99 (6%)
Query: 7 YHGKISRETGEK-LLLATGLDGSYLLRDSESVPGVYCLCVLYHGYIYTYRVSQTETGSWS 65
+ G I R EK LL + GS+L+R+SES G + L VL + YR+ + + G +
Sbjct: 117 FFGAIGRSDAEKQLLYSENKTGSFLIRESESQKGEFSLSVLDGAVVKHYRIKRLDEGGFF 176
Query: 66 AETAPGVHKRYFRKIKNLISAFQKPDQGIVIPLQYPVEK 104
+R F + +S + K G+ + L P K
Sbjct: 177 L-----TRRRIFSTLNEFVSHYTKTSDGLCVKLGKPCLK 210
>gi|187475373 c-src tyrosine kinase [Homo sapiens]
Length = 450
Score = 44.7 bits (104), Expect = 2e-05
Identities = 29/95 (30%), Positives = 44/95 (46%), Gaps = 7/95 (7%)
Query: 7 YHGKISRETGEKLLLATGLDGSYLLRDSESVPGVYCLCVLYHGYIYTYRVSQTETGSWSA 66
+HGKI+RE E+LL G +L+R+S + PG Y LCV G + YR+ + A
Sbjct: 83 FHGKITREQAERLLYPPET-GLFLVRESTNYPGDYTLCVSCDGKVEHYRI------MYHA 135
Query: 67 ETAPGVHKRYFRKIKNLISAFQKPDQGIVIPLQYP 101
+ YF + L+ + G+ L P
Sbjct: 136 SKLSIDEEVYFENLMQLVEHYTSDADGLCTRLIKP 170
>gi|4758078 c-src tyrosine kinase [Homo sapiens]
Length = 450
Score = 44.7 bits (104), Expect = 2e-05
Identities = 29/95 (30%), Positives = 44/95 (46%), Gaps = 7/95 (7%)
Query: 7 YHGKISRETGEKLLLATGLDGSYLLRDSESVPGVYCLCVLYHGYIYTYRVSQTETGSWSA 66
+HGKI+RE E+LL G +L+R+S + PG Y LCV G + YR+ + A
Sbjct: 83 FHGKITREQAERLLYPPET-GLFLVRESTNYPGDYTLCVSCDGKVEHYRI------MYHA 135
Query: 67 ETAPGVHKRYFRKIKNLISAFQKPDQGIVIPLQYP 101
+ YF + L+ + G+ L P
Sbjct: 136 SKLSIDEEVYFENLMQLVEHYTSDADGLCTRLIKP 170
>gi|15718680 IL2-inducible T-cell kinase [Homo sapiens]
Length = 620
Score = 43.9 bits (102), Expect = 3e-05
Identities = 34/103 (33%), Positives = 48/103 (46%), Gaps = 11/103 (10%)
Query: 7 YHGKISRETGEKLLLATGLDGSYLLRDSESVPGVYCLCVLYHGY-------IYTYRVSQT 59
Y+ ISR+ EKLLL TG +G++++RDS + G Y + V I Y + +T
Sbjct: 240 YNKSISRDKAEKLLLDTGKEGAFMVRDSRTA-GTYTVSVFTKAVVSENNPCIKHYHIKET 298
Query: 60 ETGSWSAETAPGVHKRYFRKIKNLISAFQKPDQGIVIPLQYPV 102
A K F I LI+ Q G+V L+YPV
Sbjct: 299 NDNPKRYYVA---EKYVFDSIPLLINYHQHNGGGLVTRLRYPV 338
>gi|48762697 growth factor receptor-bound protein 10 isoform c [Homo
sapiens]
Length = 536
Score = 43.5 bits (101), Expect = 4e-05
Identities = 21/55 (38%), Positives = 34/55 (61%), Gaps = 1/55 (1%)
Query: 7 YHGKISRETGEKLLLATGL-DGSYLLRDSESVPGVYCLCVLYHGYIYTYRVSQTE 60
+HG+ISRE +++ GL DG +LLRDS+S P + L + +H I +++ E
Sbjct: 436 FHGRISREESHRIIKQQGLVDGLFLLRDSQSNPKAFVLTLCHHQKIKNFQILPCE 490
>gi|48762695 growth factor receptor-bound protein 10 isoform c [Homo
sapiens]
Length = 536
Score = 43.5 bits (101), Expect = 4e-05
Identities = 21/55 (38%), Positives = 34/55 (61%), Gaps = 1/55 (1%)
Query: 7 YHGKISRETGEKLLLATGL-DGSYLLRDSESVPGVYCLCVLYHGYIYTYRVSQTE 60
+HG+ISRE +++ GL DG +LLRDS+S P + L + +H I +++ E
Sbjct: 436 FHGRISREESHRIIKQQGLVDGLFLLRDSQSNPKAFVLTLCHHQKIKNFQILPCE 490
>gi|48762693 growth factor receptor-bound protein 10 isoform b [Homo
sapiens]
Length = 548
Score = 43.5 bits (101), Expect = 4e-05
Identities = 21/55 (38%), Positives = 34/55 (61%), Gaps = 1/55 (1%)
Query: 7 YHGKISRETGEKLLLATGL-DGSYLLRDSESVPGVYCLCVLYHGYIYTYRVSQTE 60
+HG+ISRE +++ GL DG +LLRDS+S P + L + +H I +++ E
Sbjct: 448 FHGRISREESHRIIKQQGLVDGLFLLRDSQSNPKAFVLTLCHHQKIKNFQILPCE 502
>gi|48762679 growth factor receptor-bound protein 10 isoform a [Homo
sapiens]
Length = 594
Score = 43.5 bits (101), Expect = 4e-05
Identities = 21/55 (38%), Positives = 34/55 (61%), Gaps = 1/55 (1%)
Query: 7 YHGKISRETGEKLLLATGL-DGSYLLRDSESVPGVYCLCVLYHGYIYTYRVSQTE 60
+HG+ISRE +++ GL DG +LLRDS+S P + L + +H I +++ E
Sbjct: 494 FHGRISREESHRIIKQQGLVDGLFLLRDSQSNPKAFVLTLCHHQKIKNFQILPCE 548
>gi|5729856 GRB2-related adaptor protein [Homo sapiens]
Length = 217
Score = 42.7 bits (99), Expect = 8e-05
Identities = 19/58 (32%), Positives = 36/58 (62%)
Query: 7 YHGKISRETGEKLLLATGLDGSYLLRDSESVPGVYCLCVLYHGYIYTYRVSQTETGSW 64
Y G+ISR+ E++L+ G++L+R+SES PG + + V Y + ++V + +G +
Sbjct: 61 YSGRISRQLAEEILMKRNHLGAFLIRESESSPGEFSVSVNYGDQVQHFKVLREASGKY 118
>gi|4757980 beta chimerin isoform 2 [Homo sapiens]
Length = 468
Score = 42.4 bits (98), Expect = 1e-04
Identities = 20/50 (40%), Positives = 32/50 (64%), Gaps = 2/50 (4%)
Query: 7 YHGKISRETGEKLLLATGLDGSYLLRDSESVPGVYCLCVLYHGYIYTYRV 56
+HG ISRE ++LL G++G+Y+LR+S+ PG Y L + + YR+
Sbjct: 60 FHGIISREQADELL--GGVEGAYILRESQRQPGCYTLALRFGNQTLNYRL 107
>gi|4502813 chimerin (chimaerin) 1 isoform a [Homo sapiens]
Length = 459
Score = 42.0 bits (97), Expect = 1e-04
Identities = 19/50 (38%), Positives = 31/50 (62%), Gaps = 2/50 (4%)
Query: 7 YHGKISRETGEKLLLATGLDGSYLLRDSESVPGVYCLCVLYHGYIYTYRV 56
+HG ISRE ++LL+ +GSYL+R+S+ PG Y L + + +R+
Sbjct: 50 FHGMISREAADQLLIVA--EGSYLIRESQRQPGTYTLALRFGSQTRNFRL 97
>gi|209364623 chimerin (chimaerin) 1 isoform b [Homo sapiens]
Length = 433
Score = 42.0 bits (97), Expect = 1e-04
Identities = 19/50 (38%), Positives = 31/50 (62%), Gaps = 2/50 (4%)
Query: 7 YHGKISRETGEKLLLATGLDGSYLLRDSESVPGVYCLCVLYHGYIYTYRV 56
+HG ISRE ++LL+ +GSYL+R+S+ PG Y L + + +R+
Sbjct: 50 FHGMISREAADQLLIVA--EGSYLIRESQRQPGTYTLALRFGSQTRNFRL 97
>gi|4506431 RAS p21 protein activator 1 isoform 1 [Homo sapiens]
Length = 1047
Score = 41.2 bits (95), Expect = 2e-04
Identities = 23/83 (27%), Positives = 42/83 (50%), Gaps = 6/83 (7%)
Query: 7 YHGKISRETGEKLLLATGLDGSYLLRDSESVPGVYCLCVLYHGYIYTYRVSQTETGSWSA 66
+HGKIS++ LL+ G S+L+R S++ PG Y L + I +++ T +
Sbjct: 352 FHGKISKQEAYNLLMTVGQVCSFLVRPSDNTPGDYSLYFRTNENIQRFKICPTPNNQFM- 410
Query: 67 ETAPGVHKRYFRKIKNLISAFQK 89
+ RY+ I ++I ++K
Sbjct: 411 -----MGGRYYNSIGDIIDHYRK 428
Score = 39.7 bits (91), Expect = 6e-04
Identities = 18/40 (45%), Positives = 24/40 (60%)
Query: 7 YHGKISRETGEKLLLATGLDGSYLLRDSESVPGVYCLCVL 46
YHGK+ R E+ L G GSYL+R+S+ PG + L L
Sbjct: 182 YHGKLDRTIAEERLRQAGKSGSYLIRESDRRPGSFVLSFL 221
>gi|12545406 RAS p21 protein activator 1 isoform 2 [Homo sapiens]
Length = 870
Score = 41.2 bits (95), Expect = 2e-04
Identities = 23/83 (27%), Positives = 42/83 (50%), Gaps = 6/83 (7%)
Query: 7 YHGKISRETGEKLLLATGLDGSYLLRDSESVPGVYCLCVLYHGYIYTYRVSQTETGSWSA 66
+HGKIS++ LL+ G S+L+R S++ PG Y L + I +++ T +
Sbjct: 175 FHGKISKQEAYNLLMTVGQVCSFLVRPSDNTPGDYSLYFRTNENIQRFKICPTPNNQFM- 233
Query: 67 ETAPGVHKRYFRKIKNLISAFQK 89
+ RY+ I ++I ++K
Sbjct: 234 -----MGGRYYNSIGDIIDHYRK 251
Score = 39.7 bits (91), Expect = 6e-04
Identities = 18/40 (45%), Positives = 24/40 (60%)
Query: 7 YHGKISRETGEKLLLATGLDGSYLLRDSESVPGVYCLCVL 46
YHGK+ R E+ L G GSYL+R+S+ PG + L L
Sbjct: 5 YHGKLDRTIAEERLRQAGKSGSYLIRESDRRPGSFVLSFL 44
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.317 0.135 0.403
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 4,980,113
Number of Sequences: 37866
Number of extensions: 192221
Number of successful extensions: 539
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 75
Number of HSP's successfully gapped in prelim test: 37
Number of HSP's that attempted gapping in prelim test: 424
Number of HSP's gapped (non-prelim): 121
length of query: 128
length of database: 18,247,518
effective HSP length: 90
effective length of query: 38
effective length of database: 14,839,578
effective search space: 563903964
effective search space used: 563903964
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 55 (25.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.