Guide to the Human Genome
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Search of human proteins with 4506441

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4506441 retinoblastoma binding protein 8 isoform a [Homo
sapiens]
         (897 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|42718015 retinoblastoma binding protein 8 isoform a [Homo sap...  1810   0.0  
gi|4506441 retinoblastoma binding protein 8 isoform a [Homo sapi...  1810   0.0  
gi|42718017 retinoblastoma binding protein 8 isoform b [Homo sap...  1573   0.0  
gi|24308394 hypothetical protein LOC140893 [Homo sapiens]             138   3e-32
gi|115511012 coiled-coil domain containing 136 [Homo sapiens]          54   5e-07
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]    53   1e-06
gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens]         53   1e-06
gi|41322923 plectin 1 isoform 11 [Homo sapiens]                        53   1e-06
gi|41322914 plectin 1 isoform 10 [Homo sapiens]                        53   1e-06
gi|41322919 plectin 1 isoform 8 [Homo sapiens]                         53   1e-06
gi|41322910 plectin 1 isoform 7 [Homo sapiens]                         53   1e-06
gi|41322916 plectin 1 isoform 6 [Homo sapiens]                         53   1e-06
gi|41322908 plectin 1 isoform 3 [Homo sapiens]                         53   1e-06
gi|41322912 plectin 1 isoform 2 [Homo sapiens]                         53   1e-06
gi|47607492 plectin 1 isoform 1 [Homo sapiens]                         53   1e-06
gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens]         49   2e-05
gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo sa...    46   1e-04
gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo s...    46   1e-04
gi|94538359 golgi autoantigen, golgin subfamily a, 6B [Homo sapi...    45   2e-04
gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]             45   3e-04
gi|149999352 forkhead box P2 isoform II [Homo sapiens]                 45   4e-04
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho...    45   4e-04
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho...    45   4e-04
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho...    45   4e-04
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho...    45   4e-04
gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens]    44   5e-04
gi|59806361 hypothetical protein LOC387104 [Homo sapiens]              44   5e-04
gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin ...    44   5e-04
gi|223634475 golgi autoantigen, golgin subfamily a, 6D [Homo sap...    44   7e-04
gi|17017963 forkhead box P2 isoform I [Homo sapiens]                   44   7e-04

>gi|42718015 retinoblastoma binding protein 8 isoform a [Homo
           sapiens]
          Length = 897

 Score = 1810 bits (4689), Expect = 0.0
 Identities = 897/897 (100%), Positives = 897/897 (100%)

Query: 1   MNISGSSCGSPNSADTSSDFKDLWTKLKECHDREVQGLQVKVTKLKQERILDAQRLEEFF 60
           MNISGSSCGSPNSADTSSDFKDLWTKLKECHDREVQGLQVKVTKLKQERILDAQRLEEFF
Sbjct: 1   MNISGSSCGSPNSADTSSDFKDLWTKLKECHDREVQGLQVKVTKLKQERILDAQRLEEFF 60

Query: 61  TKNQQLREQQKVLHETIKVLEDRLRAGLCDRCAVTEEHMRKKQQEFENIRQQNLKLITEL 120
           TKNQQLREQQKVLHETIKVLEDRLRAGLCDRCAVTEEHMRKKQQEFENIRQQNLKLITEL
Sbjct: 61  TKNQQLREQQKVLHETIKVLEDRLRAGLCDRCAVTEEHMRKKQQEFENIRQQNLKLITEL 120

Query: 121 MNERNTLQEENKKLSEQLQQKIENDQQHQAAELECEEDVIPDSPITAFSFSGVNRLRRKE 180
           MNERNTLQEENKKLSEQLQQKIENDQQHQAAELECEEDVIPDSPITAFSFSGVNRLRRKE
Sbjct: 121 MNERNTLQEENKKLSEQLQQKIENDQQHQAAELECEEDVIPDSPITAFSFSGVNRLRRKE 180

Query: 181 NPHVRYIEQTHTKLEHSVCANEMRKVSKSSTHPQHNPNENEILVADTYDQSQSPMAKAHG 240
           NPHVRYIEQTHTKLEHSVCANEMRKVSKSSTHPQHNPNENEILVADTYDQSQSPMAKAHG
Sbjct: 181 NPHVRYIEQTHTKLEHSVCANEMRKVSKSSTHPQHNPNENEILVADTYDQSQSPMAKAHG 240

Query: 241 TSSYTPDKSSFNLATVVAETLGLGVQEESETQGPMSPLGDELYHCLEGNHKKQPFEESTR 300
           TSSYTPDKSSFNLATVVAETLGLGVQEESETQGPMSPLGDELYHCLEGNHKKQPFEESTR
Sbjct: 241 TSSYTPDKSSFNLATVVAETLGLGVQEESETQGPMSPLGDELYHCLEGNHKKQPFEESTR 300

Query: 301 NTEDSLRFSDSTSKTPPQEELPTRVSSPVFGATSSIKSGLDLNTSLSPSLLQPGKKKHLK 360
           NTEDSLRFSDSTSKTPPQEELPTRVSSPVFGATSSIKSGLDLNTSLSPSLLQPGKKKHLK
Sbjct: 301 NTEDSLRFSDSTSKTPPQEELPTRVSSPVFGATSSIKSGLDLNTSLSPSLLQPGKKKHLK 360

Query: 361 TLPFSNTCISRLEKTRSKSEDSALFTHHSLGSEVNKIIIQSSNKQILINKNISESLGEQN 420
           TLPFSNTCISRLEKTRSKSEDSALFTHHSLGSEVNKIIIQSSNKQILINKNISESLGEQN
Sbjct: 361 TLPFSNTCISRLEKTRSKSEDSALFTHHSLGSEVNKIIIQSSNKQILINKNISESLGEQN 420

Query: 421 RTEYGKDSNTDKHLEPLKSLGGRTSKRKKTEEESEHEVSCPQASFDKENAFPFPMDNQFS 480
           RTEYGKDSNTDKHLEPLKSLGGRTSKRKKTEEESEHEVSCPQASFDKENAFPFPMDNQFS
Sbjct: 421 RTEYGKDSNTDKHLEPLKSLGGRTSKRKKTEEESEHEVSCPQASFDKENAFPFPMDNQFS 480

Query: 481 MNGDCVMDKPLDLSDRFSAIQRQEKSQGSETSKNKFRQVTLYEALKTIPKGFSSSRKASD 540
           MNGDCVMDKPLDLSDRFSAIQRQEKSQGSETSKNKFRQVTLYEALKTIPKGFSSSRKASD
Sbjct: 481 MNGDCVMDKPLDLSDRFSAIQRQEKSQGSETSKNKFRQVTLYEALKTIPKGFSSSRKASD 540

Query: 541 GNCTLPKDSPGEPCSQECIILQPLNKCSPDNKPSLQIKEENAVFKIPLRPRESLETENVL 600
           GNCTLPKDSPGEPCSQECIILQPLNKCSPDNKPSLQIKEENAVFKIPLRPRESLETENVL
Sbjct: 541 GNCTLPKDSPGEPCSQECIILQPLNKCSPDNKPSLQIKEENAVFKIPLRPRESLETENVL 600

Query: 601 DDIKSAGSHEPIKIQTRSDHGGCELASVLQLNPCRTGKIKSLQNNQDVSFENIQWSIDPG 660
           DDIKSAGSHEPIKIQTRSDHGGCELASVLQLNPCRTGKIKSLQNNQDVSFENIQWSIDPG
Sbjct: 601 DDIKSAGSHEPIKIQTRSDHGGCELASVLQLNPCRTGKIKSLQNNQDVSFENIQWSIDPG 660

Query: 661 ADLSQYKMDVTVIDTKDGSQSKLGGETVDMDCTLVSETVLLKMKKQEQKGEKSSNEERKM 720
           ADLSQYKMDVTVIDTKDGSQSKLGGETVDMDCTLVSETVLLKMKKQEQKGEKSSNEERKM
Sbjct: 661 ADLSQYKMDVTVIDTKDGSQSKLGGETVDMDCTLVSETVLLKMKKQEQKGEKSSNEERKM 720

Query: 721 NDSLEDMFDRTTHEEYESCLADSFSQAADEEEELSTATKKLHTHGDKQDKVKQKAFVEPY 780
           NDSLEDMFDRTTHEEYESCLADSFSQAADEEEELSTATKKLHTHGDKQDKVKQKAFVEPY
Sbjct: 721 NDSLEDMFDRTTHEEYESCLADSFSQAADEEEELSTATKKLHTHGDKQDKVKQKAFVEPY 780

Query: 781 FKGDERETSLQNFPHIEVVRKKEERRKLLGHTCKECEIYYADMPAEEREKKLASCSRHRF 840
           FKGDERETSLQNFPHIEVVRKKEERRKLLGHTCKECEIYYADMPAEEREKKLASCSRHRF
Sbjct: 781 FKGDERETSLQNFPHIEVVRKKEERRKLLGHTCKECEIYYADMPAEEREKKLASCSRHRF 840

Query: 841 RYIPPNTPENFWEVGFPSTQTCMERGYIKEDLDPCPRPKRRQPYNAIFSPKGKEQKT 897
           RYIPPNTPENFWEVGFPSTQTCMERGYIKEDLDPCPRPKRRQPYNAIFSPKGKEQKT
Sbjct: 841 RYIPPNTPENFWEVGFPSTQTCMERGYIKEDLDPCPRPKRRQPYNAIFSPKGKEQKT 897


>gi|4506441 retinoblastoma binding protein 8 isoform a [Homo
           sapiens]
          Length = 897

 Score = 1810 bits (4689), Expect = 0.0
 Identities = 897/897 (100%), Positives = 897/897 (100%)

Query: 1   MNISGSSCGSPNSADTSSDFKDLWTKLKECHDREVQGLQVKVTKLKQERILDAQRLEEFF 60
           MNISGSSCGSPNSADTSSDFKDLWTKLKECHDREVQGLQVKVTKLKQERILDAQRLEEFF
Sbjct: 1   MNISGSSCGSPNSADTSSDFKDLWTKLKECHDREVQGLQVKVTKLKQERILDAQRLEEFF 60

Query: 61  TKNQQLREQQKVLHETIKVLEDRLRAGLCDRCAVTEEHMRKKQQEFENIRQQNLKLITEL 120
           TKNQQLREQQKVLHETIKVLEDRLRAGLCDRCAVTEEHMRKKQQEFENIRQQNLKLITEL
Sbjct: 61  TKNQQLREQQKVLHETIKVLEDRLRAGLCDRCAVTEEHMRKKQQEFENIRQQNLKLITEL 120

Query: 121 MNERNTLQEENKKLSEQLQQKIENDQQHQAAELECEEDVIPDSPITAFSFSGVNRLRRKE 180
           MNERNTLQEENKKLSEQLQQKIENDQQHQAAELECEEDVIPDSPITAFSFSGVNRLRRKE
Sbjct: 121 MNERNTLQEENKKLSEQLQQKIENDQQHQAAELECEEDVIPDSPITAFSFSGVNRLRRKE 180

Query: 181 NPHVRYIEQTHTKLEHSVCANEMRKVSKSSTHPQHNPNENEILVADTYDQSQSPMAKAHG 240
           NPHVRYIEQTHTKLEHSVCANEMRKVSKSSTHPQHNPNENEILVADTYDQSQSPMAKAHG
Sbjct: 181 NPHVRYIEQTHTKLEHSVCANEMRKVSKSSTHPQHNPNENEILVADTYDQSQSPMAKAHG 240

Query: 241 TSSYTPDKSSFNLATVVAETLGLGVQEESETQGPMSPLGDELYHCLEGNHKKQPFEESTR 300
           TSSYTPDKSSFNLATVVAETLGLGVQEESETQGPMSPLGDELYHCLEGNHKKQPFEESTR
Sbjct: 241 TSSYTPDKSSFNLATVVAETLGLGVQEESETQGPMSPLGDELYHCLEGNHKKQPFEESTR 300

Query: 301 NTEDSLRFSDSTSKTPPQEELPTRVSSPVFGATSSIKSGLDLNTSLSPSLLQPGKKKHLK 360
           NTEDSLRFSDSTSKTPPQEELPTRVSSPVFGATSSIKSGLDLNTSLSPSLLQPGKKKHLK
Sbjct: 301 NTEDSLRFSDSTSKTPPQEELPTRVSSPVFGATSSIKSGLDLNTSLSPSLLQPGKKKHLK 360

Query: 361 TLPFSNTCISRLEKTRSKSEDSALFTHHSLGSEVNKIIIQSSNKQILINKNISESLGEQN 420
           TLPFSNTCISRLEKTRSKSEDSALFTHHSLGSEVNKIIIQSSNKQILINKNISESLGEQN
Sbjct: 361 TLPFSNTCISRLEKTRSKSEDSALFTHHSLGSEVNKIIIQSSNKQILINKNISESLGEQN 420

Query: 421 RTEYGKDSNTDKHLEPLKSLGGRTSKRKKTEEESEHEVSCPQASFDKENAFPFPMDNQFS 480
           RTEYGKDSNTDKHLEPLKSLGGRTSKRKKTEEESEHEVSCPQASFDKENAFPFPMDNQFS
Sbjct: 421 RTEYGKDSNTDKHLEPLKSLGGRTSKRKKTEEESEHEVSCPQASFDKENAFPFPMDNQFS 480

Query: 481 MNGDCVMDKPLDLSDRFSAIQRQEKSQGSETSKNKFRQVTLYEALKTIPKGFSSSRKASD 540
           MNGDCVMDKPLDLSDRFSAIQRQEKSQGSETSKNKFRQVTLYEALKTIPKGFSSSRKASD
Sbjct: 481 MNGDCVMDKPLDLSDRFSAIQRQEKSQGSETSKNKFRQVTLYEALKTIPKGFSSSRKASD 540

Query: 541 GNCTLPKDSPGEPCSQECIILQPLNKCSPDNKPSLQIKEENAVFKIPLRPRESLETENVL 600
           GNCTLPKDSPGEPCSQECIILQPLNKCSPDNKPSLQIKEENAVFKIPLRPRESLETENVL
Sbjct: 541 GNCTLPKDSPGEPCSQECIILQPLNKCSPDNKPSLQIKEENAVFKIPLRPRESLETENVL 600

Query: 601 DDIKSAGSHEPIKIQTRSDHGGCELASVLQLNPCRTGKIKSLQNNQDVSFENIQWSIDPG 660
           DDIKSAGSHEPIKIQTRSDHGGCELASVLQLNPCRTGKIKSLQNNQDVSFENIQWSIDPG
Sbjct: 601 DDIKSAGSHEPIKIQTRSDHGGCELASVLQLNPCRTGKIKSLQNNQDVSFENIQWSIDPG 660

Query: 661 ADLSQYKMDVTVIDTKDGSQSKLGGETVDMDCTLVSETVLLKMKKQEQKGEKSSNEERKM 720
           ADLSQYKMDVTVIDTKDGSQSKLGGETVDMDCTLVSETVLLKMKKQEQKGEKSSNEERKM
Sbjct: 661 ADLSQYKMDVTVIDTKDGSQSKLGGETVDMDCTLVSETVLLKMKKQEQKGEKSSNEERKM 720

Query: 721 NDSLEDMFDRTTHEEYESCLADSFSQAADEEEELSTATKKLHTHGDKQDKVKQKAFVEPY 780
           NDSLEDMFDRTTHEEYESCLADSFSQAADEEEELSTATKKLHTHGDKQDKVKQKAFVEPY
Sbjct: 721 NDSLEDMFDRTTHEEYESCLADSFSQAADEEEELSTATKKLHTHGDKQDKVKQKAFVEPY 780

Query: 781 FKGDERETSLQNFPHIEVVRKKEERRKLLGHTCKECEIYYADMPAEEREKKLASCSRHRF 840
           FKGDERETSLQNFPHIEVVRKKEERRKLLGHTCKECEIYYADMPAEEREKKLASCSRHRF
Sbjct: 781 FKGDERETSLQNFPHIEVVRKKEERRKLLGHTCKECEIYYADMPAEEREKKLASCSRHRF 840

Query: 841 RYIPPNTPENFWEVGFPSTQTCMERGYIKEDLDPCPRPKRRQPYNAIFSPKGKEQKT 897
           RYIPPNTPENFWEVGFPSTQTCMERGYIKEDLDPCPRPKRRQPYNAIFSPKGKEQKT
Sbjct: 841 RYIPPNTPENFWEVGFPSTQTCMERGYIKEDLDPCPRPKRRQPYNAIFSPKGKEQKT 897


>gi|42718017 retinoblastoma binding protein 8 isoform b [Homo
           sapiens]
          Length = 867

 Score = 1573 bits (4072), Expect = 0.0
 Identities = 789/809 (97%), Positives = 796/809 (98%), Gaps = 8/809 (0%)

Query: 1   MNISGSSCGSPNSADTSSDFKDLWTKLKECHDREVQGLQVKVTKLKQERILDAQRLEEFF 60
           MNISGSSCGSPNSADTSSDFKDLWTKLKECHDREVQGLQVKVTKLKQERILDAQRLEEFF
Sbjct: 1   MNISGSSCGSPNSADTSSDFKDLWTKLKECHDREVQGLQVKVTKLKQERILDAQRLEEFF 60

Query: 61  TKNQQLREQQKVLHETIKVLEDRLRAGLCDRCAVTEEHMRKKQQEFENIRQQNLKLITEL 120
           TKNQQLREQQKVLHETIKVLEDRLRAGLCDRCAVTEEHMRKKQQEFENIRQQNLKLITEL
Sbjct: 61  TKNQQLREQQKVLHETIKVLEDRLRAGLCDRCAVTEEHMRKKQQEFENIRQQNLKLITEL 120

Query: 121 MNERNTLQEENKKLSEQLQQKIENDQQHQAAELECEEDVIPDSPITAFSFSGVNRLRRKE 180
           MNERNTLQEENKKLSEQLQQKIENDQQHQAAELECEEDVIPDSPITAFSFSGVNRLRRKE
Sbjct: 121 MNERNTLQEENKKLSEQLQQKIENDQQHQAAELECEEDVIPDSPITAFSFSGVNRLRRKE 180

Query: 181 NPHVRYIEQTHTKLEHSVCANEMRKVSKSSTHPQHNPNENEILVADTYDQSQSPMAKAHG 240
           NPHVRYIEQTHTKLEHSVCANEMRKVSKSSTHPQHNPNENEILVADTYDQSQSPMAKAHG
Sbjct: 181 NPHVRYIEQTHTKLEHSVCANEMRKVSKSSTHPQHNPNENEILVADTYDQSQSPMAKAHG 240

Query: 241 TSSYTPDKSSFNLATVVAETLGLGVQEESETQGPMSPLGDELYHCLEGNHKKQPFEESTR 300
           TSSYTPDKSSFNLATVVAETLGLGVQEESETQGPMSPLGDELYHCLEGNHKKQPFEESTR
Sbjct: 241 TSSYTPDKSSFNLATVVAETLGLGVQEESETQGPMSPLGDELYHCLEGNHKKQPFEESTR 300

Query: 301 NTEDSLRFSDSTSKTPPQEELPTRVSSPVFGATSSIKSGLDLNTSLSPSLLQPGKKKHLK 360
           NTEDSLRFSDSTSKTPPQEELPTRVSSPVFGATSSIKSGLDLNTSLSPSLLQPGKKKHLK
Sbjct: 301 NTEDSLRFSDSTSKTPPQEELPTRVSSPVFGATSSIKSGLDLNTSLSPSLLQPGKKKHLK 360

Query: 361 TLPFSNTCISRLEKTRSKSEDSALFTHHSLGSEVNKIIIQSSNKQILINKNISESLGEQN 420
           TLPFSNTCISRLEKTRSKSEDSALFTHHSLGSEVNKIIIQSSNKQILINKNISESLGEQN
Sbjct: 361 TLPFSNTCISRLEKTRSKSEDSALFTHHSLGSEVNKIIIQSSNKQILINKNISESLGEQN 420

Query: 421 RTEYGKDSNTDKHLEPLKSLGGRTSKRKKTEEESEHEVSCPQASFDKENAFPFPMDNQFS 480
           RTEYGKDSNTDKHLEPLKSLGGRTSKRKKTEEESEHEVSCPQASFDKENAFPFPMDNQFS
Sbjct: 421 RTEYGKDSNTDKHLEPLKSLGGRTSKRKKTEEESEHEVSCPQASFDKENAFPFPMDNQFS 480

Query: 481 MNGDCVMDKPLDLSDRFSAIQRQEKSQGSETSKNKFRQVTLYEALKTIPKGFSSSRKASD 540
           MNGDCVMDKPLDLSDRFSAIQRQEKSQGSETSKNKFRQVTLYEALKTIPKGFSSSRKASD
Sbjct: 481 MNGDCVMDKPLDLSDRFSAIQRQEKSQGSETSKNKFRQVTLYEALKTIPKGFSSSRKASD 540

Query: 541 GNCTLPKDSPGEPCSQECIILQPLNKCSPDNKPSLQIKEENAVFKIPLRPRESLETENVL 600
           GNCTLPKDSPGEPCSQECIILQPLNKCSPDNKPSLQIKEENAVFKIPLRPRESLETENVL
Sbjct: 541 GNCTLPKDSPGEPCSQECIILQPLNKCSPDNKPSLQIKEENAVFKIPLRPRESLETENVL 600

Query: 601 DDIKSAGSHEPIKIQTRSDHGGCELASVLQLNPCRTGKIKSLQNNQDVSFENIQWSIDPG 660
           DDIKSAGSHEPIKIQTRSDHGGCELASVLQLNPCRTGKIKSLQNNQDVSFENIQWSIDPG
Sbjct: 601 DDIKSAGSHEPIKIQTRSDHGGCELASVLQLNPCRTGKIKSLQNNQDVSFENIQWSIDPG 660

Query: 661 ADLSQYKMDVTVIDTKDGSQSKLGGETVDMDCTLVSETVLLKMKKQEQKGEKSSNEERKM 720
           ADLSQYKMDVTVIDTKDGSQSKLGGETVDMDCTLVSETVLLKMKKQEQKGEKSSNEERKM
Sbjct: 661 ADLSQYKMDVTVIDTKDGSQSKLGGETVDMDCTLVSETVLLKMKKQEQKGEKSSNEERKM 720

Query: 721 NDSLEDMFDRTTHEEYESCLADSFSQAADEEEELSTATKKLHTHGDKQDKVKQKAFVEPY 780
           NDSLEDMFDRTTHEEYESCLADSFSQAADEEEELSTATKKLHTHGDKQDKVKQKAFVEPY
Sbjct: 721 NDSLEDMFDRTTHEEYESCLADSFSQAADEEEELSTATKKLHTHGDKQDKVKQKAFVEPY 780

Query: 781 FKGDERETSLQNFPHIEVVRKKEERRKLL 809
           FKGDE          +++ ++K+E+R  L
Sbjct: 781 FKGDE--------SIMQICQQKKEKRNWL 801


>gi|24308394 hypothetical protein LOC140893 [Homo sapiens]
          Length = 664

 Score =  138 bits (347), Expect = 3e-32
 Identities = 80/173 (46%), Positives = 108/173 (62%), Gaps = 4/173 (2%)

Query: 20  FKDLWTKLKECHDREVQGLQVKVTKLKQERILDAQRLEEFFTKNQQLREQQKVLHETIKV 79
           F +   +LKE H++EV GLQ K+ +L  ER  DAQR+EE F+KN QLREQQK L E ++V
Sbjct: 4   FMESLNRLKEIHEKEVLGLQNKLLELNSERCRDAQRIEELFSKNHQLREQQKTLKENLRV 63

Query: 80  LEDRLRAGLCDRCAVTEEHMRKKQQEFENIRQQNLKLITELMNERNTLQEENKKLSEQLQ 139
           LE+RLRAGLCDRC VT+E  RK+QQEFE+   QNL+ I  L NE N L+EEN+ L E+++
Sbjct: 64  LENRLRAGLCDRCMVTQELARKRQQEFESSHLQNLQRIFILTNEMNGLKEENETLKEEVK 123

Query: 140 Q-KIENDQQHQAAELECEEDVIPDSPITAFSFSGVNRLRRKENPHVRYIEQTH 191
           + ++  D+    A+   E    P SP+   S  G   +  K        E+ H
Sbjct: 124 RLRVLGDRPKPRAK---EGTSDPPSPLLLPSPGGWKAITEKPPGGHEEAEEDH 173


>gi|115511012 coiled-coil domain containing 136 [Homo sapiens]
          Length = 1154

 Score = 54.3 bits (129), Expect = 5e-07
 Identities = 110/506 (21%), Positives = 195/506 (38%), Gaps = 73/506 (14%)

Query: 34  EVQGLQVKVTKLKQERILDAQRLEEFFTKNQQLREQQKVLHETIKVLEDRLRAGLCDRCA 93
           E+QGL      L+ ER+  AQ+ E F  + QQL+ + + L E I +LE    + L +   
Sbjct: 88  ELQGL------LEDERLASAQQAEVFTKQIQQLQGELRSLREEISLLEHEKESELKE--- 138

Query: 94  VTEEHMRKKQQEFENIRQQNLKLITELMNERNTLQEENKKLSEQLQ--QKIENDQQHQAA 151
             E+ +   Q E +++RQ      TE  ++  +LQE+  ++  +L+  ++I  D + + A
Sbjct: 139 -IEQELHLAQAEIQSLRQAAEDSATEHESDIASLQEDLCRMQNELEDMERIRGDYEMEIA 197

Query: 152 ELECEEDV---IPDSPITAFSFSGVNRLRRKENPHVRYIEQTHTKLEHSVCANEMRKVSK 208
            L  E ++    P   +    +SG+    ++      ++ + +  L+           S 
Sbjct: 198 SLRAEMEMKSSEPSGSLGLSDYSGLQEELQELRERYHFLNEEYRALQE----------SN 247

Query: 209 SSTHPQHNPNENEILVADTYDQSQSPMAKAHGTSSYTPDKSSFNLATVVAETLGLGVQEE 268
           SS   Q    E+E     T    QS         S T  +  F       + L   +++ 
Sbjct: 248 SSLTGQLADLESERTQRATERWLQSQTLSMTSAESQT-SEMDFLEPDPEMQLLRQQLRDA 306

Query: 269 SETQGPMSPLGDELYHCLEG-NHKKQPFEESTRNTE--------DSLRFSDSTSKTPPQE 319
            E    M     EL   LE   H +Q  EE  R  +        + LRF  S S T   E
Sbjct: 307 EEQMHGMKNKCQELCCELEELQHHRQVSEEEQRRLQRELKCAQNEVLRFQTSHSVT-QNE 365

Query: 320 ELPTRVSSPVFGATSS-------IKSGLDLNTSLSPSLLQPGKKKHLKTLPFSNTCISRL 372
           EL +R+ +      +S       +K  L L T L    +    K  L         + RL
Sbjct: 366 ELKSRLCTLQKKYDTSQDEQNELLKMQLQLQTELRQLKVM---KSTLVENQSEKELLCRL 422

Query: 373 EKTRSKSEDSALFTHHSLGSEVNKII---------IQSSNKQILINKNISESLGEQNRTE 423
           +K            H ++  E  K++         +Q    ++   ++   S  E N   
Sbjct: 423 QKLH--------LQHQNVTCEKEKLLERQQQLQEELQCHEAELQHLRDTVASFKESNE-- 472

Query: 424 YGKDSNTDKHLEPLKSL----GGRTSKRKKTEEESEHEVSCPQASFDKENA-FPFPMDNQ 478
             KD+ T   L+ +K L         ++K   ++ E ++   Q    +  A  P P D  
Sbjct: 473 --KDTETHAQLQEMKQLYQASKDELERQKHMYDQLEQDLLLCQLELKELKASHPIPEDKG 530

Query: 479 FSMNG-DCVMDKPLDLSDRFSAIQRQ 503
              N  D ++ +  +L +++ A Q++
Sbjct: 531 KCANKCDTLLSRLTELQEKYKASQKE 556



 Score = 33.9 bits (76), Expect = 0.70
 Identities = 29/141 (20%), Positives = 62/141 (43%), Gaps = 33/141 (23%)

Query: 29  ECHDREVQGLQVKVTKLKQERILDA------QRLEEFFTKNQQLREQQKVLHETIK---- 78
           +CH+ E+Q L+  V   K+    D       Q +++ +  ++   E+QK +++ ++    
Sbjct: 451 QCHEAELQHLRDTVASFKESNEKDTETHAQLQEMKQLYQASKDELERQKHMYDQLEQDLL 510

Query: 79  --------------VLEDRLR-AGLCD----RCAVTEEHMRKKQQEFENIRQQNLKLITE 119
                         + ED+ + A  CD    R    +E  +  Q+E   ++ +      E
Sbjct: 511 LCQLELKELKASHPIPEDKGKCANKCDTLLSRLTELQEKYKASQKEMGQLQMEQC----E 566

Query: 120 LMNERNTLQEENKKLSEQLQQ 140
           L+ ++  +QEE  +L E+L +
Sbjct: 567 LLEDQRRMQEEQGQLQEELHR 587


>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
          Length = 1976

 Score = 53.1 bits (126), Expect = 1e-06
 Identities = 100/561 (17%), Positives = 217/561 (38%), Gaps = 82/561 (14%)

Query: 32   DREVQGLQVKVTKLKQERILDAQRLEEFFTKNQQLREQQKVLHETIKVLEDRLRAGLCDR 91
            + E+Q    ++ K+K+++      LEE   K+QQL E++ +L E ++         L   
Sbjct: 851  EEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQA-----ETELFAE 905

Query: 92   CAVTEEHMRKKQQEFENIRQQNLKLITELMNERNTLQEENKKLSEQLQQKIENDQQHQAA 151
                   +  K+QE E I       + E       LQ E KK+   +Q   E   + + A
Sbjct: 906  AEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGA 965

Query: 152  ELECE-EDVIPDSPITAFSFSGVNRLRRKENPHVRYIEQTHTKLEH-SVCANEMRKVSKS 209
              + + E V  ++ I          +   E+ + ++I++     +  + C++++ +  + 
Sbjct: 966  RQKLQLEKVTAEAKIKKME----EEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEK 1021

Query: 210  STHPQHNPNENEILVAD----------TYDQSQSPMAKAHGTSSYTPDKSSFNLATVVAE 259
            + +     N+ E++++D          T  + +    K  G ++   D+ +   A +   
Sbjct: 1022 AKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDEL 1081

Query: 260  TLGLGVQEESETQGPMSPLGDELYH---CLEGNHKKQ----------PFEESTRNTEDSL 306
             L L  +EE E QG ++   DE  H    L+   + Q            E+++RN  +  
Sbjct: 1082 KLQLAKKEE-ELQGALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQ 1140

Query: 307  R-------------FSDSTSKTPPQEELPTRVSSPVFGATSSIKSGLDLNTSLSPSLLQP 353
            +               D+   T  Q+EL T+    V    + +K  L+  T    + +Q 
Sbjct: 1141 KRDLSEELEALKTELEDTLDTTAAQQELRTKREQEV----AELKKALEEETKNHEAQIQD 1196

Query: 354  GKKKHLKTLPFSNTCISRLEKTRSKSEDSALFTHHSLGSEVNKIIIQSSNKQILINKNIS 413
             +++H           + LE+   + E +  F       E NK  +++ NK++     + 
Sbjct: 1197 MRQRH----------ATALEELSEQLEQAKRF---KANLEKNKQGLETDNKELACEVKVL 1243

Query: 414  ESLGEQNRTEYGKDSNTDKHLEPLKSLGGR-----TSKRKKTEEESEH------EVSCPQ 462
            + +  ++  +  K     + L    S G R       K  K + E ++      E     
Sbjct: 1244 QQVKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKG 1303

Query: 463  ASFDKENAFPFPMDNQFSMNGDCVMD---KPLDLSDRFSAIQRQEKSQGSETSKNKFRQV 519
              F K+ A    +++Q     + + +   + L+LS R   ++ ++ S   +  + +  + 
Sbjct: 1304 IKFAKDAA---SLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARK 1360

Query: 520  TLYEALKTIPKGFSSSRKASD 540
             L + +  +    + ++K  D
Sbjct: 1361 NLEKQVLALQSQLADTKKKVD 1381


>gi|22538387 A-kinase anchor protein 9 isoform 2 [Homo sapiens]
          Length = 3907

 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 170/839 (20%), Positives = 327/839 (38%), Gaps = 114/839 (13%)

Query: 28   KECHDREVQGLQVKVTKLKQERILDAQRLEEFFTKNQQLRE------------------- 68
            K   +R++Q     + +L+QE +  + RL+E   + QQ++E                   
Sbjct: 1931 KTLFERQIQEKTDIIDRLEQELLCASNRLQELEAEQQQIQEERELLSRQKEAMKAEAGPV 1990

Query: 69   QQKVLHETIKVLEDRLRAGLCDRCAVTEEHMRKKQQEFENIRQQNLKLITELMNERNT-- 126
            +Q++L ET K+++++L    C    V ++ ++K+ +  E   ++ +    EL  E+NT  
Sbjct: 1991 EQQLLQETEKLMKEKLEV-QCQAEKVRDD-LQKQVKALEIDVEEQVSRFIELEQEKNTEL 2048

Query: 127  --LQEENKKLSEQLQQKIENDQQHQAAELECEEDVI-PDSPITAFSFSGVNRLRRKENPH 183
              L+++N+ L +QL +K+      QA + E E DV   +          V R +      
Sbjct: 2049 MDLRQQNQALEKQL-EKMRKFLDEQAIDREHERDVFQQEIQKLEQQLKVVPRFQPISEHQ 2107

Query: 184  VRYIEQ--THTKLEHSVCANEMRKVSKSSTHPQHNPNENEILVADTYDQSQSPMAKAHGT 241
             R +EQ   H K +   C+  +    +     Q    E E L     +  Q+ +  A  T
Sbjct: 2108 TREVEQLANHLKEKTDKCSELLLSKEQLQRDIQERNEEIEKLEFRVRELEQALLVSA-DT 2166

Query: 242  SSYTPDKSSFNLATVVAETLGLGVQEESE------TQGPMSPLGDELYHCLEGNHKKQPF 295
                 D+  F       E L L VQ ++E       +  ++ L ++L    E    K   
Sbjct: 2167 FQKVEDRKHFGAVEAKPE-LSLEVQLQAERDAIDRKEKEITNLEEQLEQFREELENKNE- 2224

Query: 296  EESTRNTEDSLRFSDSTSKTPPQEELPTRVSSPVFGATSSIKSGLDLNTSLSPSLLQPGK 355
            E    + +  ++  +ST++    E+        +     +IK    ++T     L     
Sbjct: 2225 EVQQLHMQLEIQKKESTTRLQELEQENKLFKDDMEKLGLAIKESDAMSTQDQHVLF---- 2280

Query: 356  KKHLKTLPFSNTCISRLEKTRSKSEDSALFTHHSLGSEVNKIIIQSSNKQILINKNISES 415
             K  + +      I +L +  +K +     T  +   E    +I+    QI    +  E 
Sbjct: 2281 GKFAQIIQEKEVEIDQLNEQVTKLQQQLKITTDNKVIEEKNELIRDLETQIECLMSDQEC 2340

Query: 416  LGEQNRTEYGKDSN--TDKHLEPLKSLGGRTSKRKKTEEESEHEVSCPQASFDKENAFPF 473
            + ++NR E  +  N   +K  + L ++G +TS    +  E   E    +   D   A   
Sbjct: 2341 V-KRNREEEIEQLNEVIEKLQQELANIGQKTSMNAHSLSE---EADSLKHQLDVVIAEKL 2396

Query: 474  PMDNQF-SMNGDCVMDKPLDLSDRFSAIQRQEKSQGSETSKNKFRQVTLYEALKTIPKGF 532
             ++ Q  + N +    K +     F      + +Q ++   +  R+    E +++IP+  
Sbjct: 2397 ALEQQVETANEEMTFMKNVLKETNF------KMNQLTQELFSLKRERESVEKIQSIPE-- 2448

Query: 533  SSSRKASDGNCTLPKDSPGEPCSQECIILQPLNKCSPDNKPSLQIKEENAVFKIPLRPRE 592
            +S   A D    L KD P      E ++ +   K S +N+   +  EEN    I      
Sbjct: 2449 NSVNVAID---HLSKDKP----ELEVVLTEDALK-SLENQTYFKSFEENGKGSIINLETR 2500

Query: 593  SLETENV--------------LDDIKSAGSHEPIKIQTR--------SDHGGCELASVLQ 630
             L+ E+               + D++  G  E   +Q +         +     L S +Q
Sbjct: 2501 LLQLESTVSAKDLELTQCYKQIKDMQEQGQFETEMLQKKIVNLQKIVEEKVAAALVSQIQ 2560

Query: 631  LNPCRTGKIKSLQNNQDVSFENIQWSIDPGADLSQYKM--DVTVIDTKDGSQSKLGGETV 688
            L   +    K  Q+NQ +S E  + +I     L + ++  D++ +  +    S+L  + V
Sbjct: 2561 LEAVQE-YAKFCQDNQTISSEPERTNIQNLNQLREDELGSDISALTLR---ISELESQVV 2616

Query: 689  DMDCTLV---------------SETVLLKMKKQEQKGEKSSNEERKMNDSLEDMFDRTTH 733
            +M  +L+                E  LL+++K  +  EK   E+ K     +    +TT 
Sbjct: 2617 EMHTSLILEKEQVEIAEKNVLEKEKKLLELQKLLEGNEKKQREKEKKRSPQDVEVLKTTT 2676

Query: 734  EEYESCLADSFSQAADEEEELSTATK-KLHTHGDKQDKVKQKAFVEPYFKGDERETSLQ 791
            E + S     F    +     S ATK +L ++ +K +K++++  V+     +   TSLQ
Sbjct: 2677 ELFHSNEESGFFNELEALRAESVATKAELASYKEKAEKLQEELLVK-----ETNMTSLQ 2730



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 45/187 (24%), Positives = 87/187 (46%), Gaps = 20/187 (10%)

Query: 26  KLKECHDREVQGLQVKVTKLKQERILDAQRLEEFFTK----NQQLREQQKVLHETIKV-- 79
           K K   ++EVQ LQ+K   L+++       L+E F +    N  L++++K L + +K+  
Sbjct: 736 KEKGTLEQEVQELQLKTELLEKQMKEKENDLQEKFAQLEAENSILKDEKKTLEDMLKIHT 795

Query: 80  ---LEDRL----RAGLCDRCAVTEEHMRKKQQEFENIRQQNLKLITELMNERNTLQEENK 132
               E+RL          + +V E+ +    +E E+++QQ ++L  E+  +RNT     K
Sbjct: 796 PVSQEERLIFLDSIKSKSKDSVWEKEIEILIEENEDLKQQCIQLNEEIEKQRNTFSFAEK 855

Query: 133 KLSEQLQQKIENDQQHQAAELECEEDVIPDSPITAFSFSGVNRLRR-KENPHVRYIEQTH 191
                 Q+     Q+  A  L+ ++D+          +   ++L+   E  H++ I  T 
Sbjct: 856 NFEVNYQEL----QEEYACLLKVKDDLEDSKNKQELEYK--SKLKALNEELHLQRINPTT 909

Query: 192 TKLEHSV 198
            K++ SV
Sbjct: 910 VKMKSSV 916



 Score = 39.3 bits (90), Expect = 0.017
 Identities = 32/115 (27%), Positives = 62/115 (53%), Gaps = 4/115 (3%)

Query: 53  AQRLEEF-FTKNQQLREQQKVLHETIKVLEDRLRAGLCDRCAVTEEHMRKKQQEFENIRQ 111
           +Q++E   F K+  + +Q +++ E  K L+D  ++ +  +       + + Q+E E +RQ
Sbjct: 675 SQKIETMQFEKDNLITKQNQLILEISK-LKDLQQSLVNSKSEEMTLQINELQKEIEILRQ 733

Query: 112 QNLKLITELMNERNTLQEENKKLSEQLQQKIENDQQHQAAELECEEDVIPDSPIT 166
           +  +  T L  E   LQ + + L +Q+++K END Q + A+LE E  ++ D   T
Sbjct: 734 EEKEKGT-LEQEVQELQLKTELLEKQMKEK-ENDLQEKFAQLEAENSILKDEKKT 786



 Score = 35.4 bits (80), Expect = 0.24
 Identities = 29/109 (26%), Positives = 52/109 (47%), Gaps = 16/109 (14%)

Query: 57   EEFFTKNQQLREQQKVLHETIKVL-----------EDRLRAGLCDRCAVTEEHMRKKQQE 105
            EE F+K++    +Q + H+ I V            E++L     +     +EH    QQ 
Sbjct: 1550 EEMFSKDKTFIVRQSI-HDEISVSSMDASRQLMLNEEQLEDMRQELVRQYQEH----QQA 1604

Query: 106  FENIRQQNLKLITELMNERNTLQEENKKLSEQLQQKIENDQQHQAAELE 154
             E +RQ +++ +     ++  LQEE K+L+ QL Q+   D ++  +E E
Sbjct: 1605 TELLRQAHMRQMERQREDQEQLQEEIKRLNRQLAQRSSIDNENLVSERE 1653



 Score = 31.2 bits (69), Expect = 4.5
 Identities = 41/218 (18%), Positives = 91/218 (41%), Gaps = 48/218 (22%)

Query: 32  DREVQGLQVKVTKLKQERILDAQRLEEFFTKNQQLREQ------------QKVLHETIKV 79
           ++E++ +++++T  KQ+    ++ +++     ++L+++            Q++  ET + 
Sbjct: 370 NQEIKNMKLELTNSKQKERQSSEEIKQLMGTVEELQKRNHKDSQFETDIVQRMEQETQRK 429

Query: 80  LEDRLRAGLCD----------------RCAVTEEHMRKKQQEFEN---------IRQQNL 114
           LE +LRA L +                  A  EE   + + E EN         + +  +
Sbjct: 430 LE-QLRAELDEMYGQQIVQMKQELIRQHMAQMEEMKTRHKGEMENALRSYSNITVNEDQI 488

Query: 115 KLITELMNERNTLQEENKKLSEQLQQKIENDQQHQAAELECEEDVIPDSPITAFSFSGVN 174
           KL+   +NE N   ++     E+L++++    + + A     ED++ +    +FS   + 
Sbjct: 489 KLMNVAINELNIKLQDTNSQKEKLKEELGLILEEKCALQRQLEDLVEE---LSFSREQIQ 545

Query: 175 RLRRKENPHVRYIEQTHTKLE-------HSVCANEMRK 205
           R R+        + + H  L          V A+E RK
Sbjct: 546 RARQTIAEQESKLNEAHKSLSTVEDLKAEIVSASESRK 583



 Score = 31.2 bits (69), Expect = 4.5
 Identities = 22/74 (29%), Positives = 36/74 (48%), Gaps = 14/74 (18%)

Query: 96   EEHMRKKQQEFENIRQQNLKLITELMNERNTLQE----ENKKLSEQ----------LQQK 141
            EE++ K++ EF +I  Q   L    +N ++ L      E  KL EQ          LQQ+
Sbjct: 1294 EENLPKEETEFLSIHSQMTNLEDIDVNHKSKLSSLQDLEKTKLEEQVQELESLISSLQQQ 1353

Query: 142  IENDQQHQAAELEC 155
            ++  +Q+  AE+ C
Sbjct: 1354 LKETEQNYEAEIHC 1367


>gi|41322923 plectin 1 isoform 11 [Homo sapiens]
          Length = 4547

 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 44/140 (31%), Positives = 72/140 (51%), Gaps = 19/140 (13%)

Query: 27   LKECHDREVQGLQVKVTKLKQERILDAQR--LEEFF----TKNQQLREQQKVLHETIKVL 80
            L+E    +   L  K + L++ER ++ ++  LE+ F     K QQLRE+Q+   + ++  
Sbjct: 2485 LQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQE 2544

Query: 81   EDRLRAGLCD---RCAVTEEHMRKKQQEFENIRQQNLKLITELMNERNTLQEENKKLSEQ 137
              RL A + +   R    EE +R+KQ+E + + QQ          +   L EEN++L EQ
Sbjct: 2545 RQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQR-------RQQEELLAEENQRLREQ 2597

Query: 138  LQQKIENDQQHQAAELECEE 157
            LQ     ++QH+AA    EE
Sbjct: 2598 LQLL---EEQHRAALAHSEE 2614



 Score = 39.7 bits (91), Expect = 0.013
 Identities = 35/136 (25%), Positives = 70/136 (51%), Gaps = 8/136 (5%)

Query: 28   KECHDREVQGLQVKVTKLK---QERIL-DAQRLEE-FFTKNQQLREQQKVLHETIKVLED 82
            KE   +E + LQ+K  +++   QE++L + Q L++ F ++   L ++++ + +    LE 
Sbjct: 2459 KEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQ 2518

Query: 83   RLRAGLCDRCAVTEEHMRKKQQEFENIRQQNLKLITELMNERNTLQEENKKLSEQLQQKI 142
              +  +     + EE  R+ QQ+ E  RQ+ +  + E    ++  +E  ++  E+LQQ  
Sbjct: 2519 LFQDEVAKAQQLREEQQRQ-QQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQL- 2576

Query: 143  ENDQQHQAAELECEED 158
               Q+ Q  EL  EE+
Sbjct: 2577 -EQQRRQQEELLAEEN 2591



 Score = 32.0 bits (71), Expect = 2.6
 Identities = 27/109 (24%), Positives = 48/109 (44%), Gaps = 9/109 (8%)

Query: 704  KKQEQKGEKSSNEERKMNDSLEDMFDRTTHEEYESCLADSFSQAADEEEELSTATKKLHT 763
            +++ Q+ E  + E +++ + L+ +      E++ + LA S    A +      ATK L  
Sbjct: 2578 QQRRQQEELLAEENQRLREQLQLL-----EEQHRAALAHSEEVTASQV----AATKTLPN 2628

Query: 764  HGDKQDKVKQKAFVEPYFKGDERETSLQNFPHIEVVRKKEERRKLLGHT 812
              D  D    +A  E  F G  R+ S Q      ++  +E +R   GHT
Sbjct: 2629 GRDALDGPAAEAEPEHSFDGLRRKVSAQRLQEAGILSAEELQRLAQGHT 2677


>gi|41322914 plectin 1 isoform 10 [Homo sapiens]
          Length = 4551

 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 44/140 (31%), Positives = 72/140 (51%), Gaps = 19/140 (13%)

Query: 27   LKECHDREVQGLQVKVTKLKQERILDAQR--LEEFF----TKNQQLREQQKVLHETIKVL 80
            L+E    +   L  K + L++ER ++ ++  LE+ F     K QQLRE+Q+   + ++  
Sbjct: 2489 LQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQE 2548

Query: 81   EDRLRAGLCD---RCAVTEEHMRKKQQEFENIRQQNLKLITELMNERNTLQEENKKLSEQ 137
              RL A + +   R    EE +R+KQ+E + + QQ          +   L EEN++L EQ
Sbjct: 2549 RQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQR-------RQQEELLAEENQRLREQ 2601

Query: 138  LQQKIENDQQHQAAELECEE 157
            LQ     ++QH+AA    EE
Sbjct: 2602 LQLL---EEQHRAALAHSEE 2618



 Score = 39.7 bits (91), Expect = 0.013
 Identities = 35/136 (25%), Positives = 70/136 (51%), Gaps = 8/136 (5%)

Query: 28   KECHDREVQGLQVKVTKLK---QERIL-DAQRLEE-FFTKNQQLREQQKVLHETIKVLED 82
            KE   +E + LQ+K  +++   QE++L + Q L++ F ++   L ++++ + +    LE 
Sbjct: 2463 KEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQ 2522

Query: 83   RLRAGLCDRCAVTEEHMRKKQQEFENIRQQNLKLITELMNERNTLQEENKKLSEQLQQKI 142
              +  +     + EE  R+ QQ+ E  RQ+ +  + E    ++  +E  ++  E+LQQ  
Sbjct: 2523 LFQDEVAKAQQLREEQQRQ-QQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQL- 2580

Query: 143  ENDQQHQAAELECEED 158
               Q+ Q  EL  EE+
Sbjct: 2581 -EQQRRQQEELLAEEN 2595



 Score = 32.0 bits (71), Expect = 2.6
 Identities = 27/109 (24%), Positives = 48/109 (44%), Gaps = 9/109 (8%)

Query: 704  KKQEQKGEKSSNEERKMNDSLEDMFDRTTHEEYESCLADSFSQAADEEEELSTATKKLHT 763
            +++ Q+ E  + E +++ + L+ +      E++ + LA S    A +      ATK L  
Sbjct: 2582 QQRRQQEELLAEENQRLREQLQLL-----EEQHRAALAHSEEVTASQV----AATKTLPN 2632

Query: 764  HGDKQDKVKQKAFVEPYFKGDERETSLQNFPHIEVVRKKEERRKLLGHT 812
              D  D    +A  E  F G  R+ S Q      ++  +E +R   GHT
Sbjct: 2633 GRDALDGPAAEAEPEHSFDGLRRKVSAQRLQEAGILSAEELQRLAQGHT 2681


>gi|41322919 plectin 1 isoform 8 [Homo sapiens]
          Length = 4547

 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 44/140 (31%), Positives = 72/140 (51%), Gaps = 19/140 (13%)

Query: 27   LKECHDREVQGLQVKVTKLKQERILDAQR--LEEFF----TKNQQLREQQKVLHETIKVL 80
            L+E    +   L  K + L++ER ++ ++  LE+ F     K QQLRE+Q+   + ++  
Sbjct: 2485 LQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQE 2544

Query: 81   EDRLRAGLCD---RCAVTEEHMRKKQQEFENIRQQNLKLITELMNERNTLQEENKKLSEQ 137
              RL A + +   R    EE +R+KQ+E + + QQ          +   L EEN++L EQ
Sbjct: 2545 RQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQR-------RQQEELLAEENQRLREQ 2597

Query: 138  LQQKIENDQQHQAAELECEE 157
            LQ     ++QH+AA    EE
Sbjct: 2598 LQLL---EEQHRAALAHSEE 2614



 Score = 39.7 bits (91), Expect = 0.013
 Identities = 35/136 (25%), Positives = 70/136 (51%), Gaps = 8/136 (5%)

Query: 28   KECHDREVQGLQVKVTKLK---QERIL-DAQRLEE-FFTKNQQLREQQKVLHETIKVLED 82
            KE   +E + LQ+K  +++   QE++L + Q L++ F ++   L ++++ + +    LE 
Sbjct: 2459 KEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQ 2518

Query: 83   RLRAGLCDRCAVTEEHMRKKQQEFENIRQQNLKLITELMNERNTLQEENKKLSEQLQQKI 142
              +  +     + EE  R+ QQ+ E  RQ+ +  + E    ++  +E  ++  E+LQQ  
Sbjct: 2519 LFQDEVAKAQQLREEQQRQ-QQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQL- 2576

Query: 143  ENDQQHQAAELECEED 158
               Q+ Q  EL  EE+
Sbjct: 2577 -EQQRRQQEELLAEEN 2591



 Score = 32.0 bits (71), Expect = 2.6
 Identities = 27/109 (24%), Positives = 48/109 (44%), Gaps = 9/109 (8%)

Query: 704  KKQEQKGEKSSNEERKMNDSLEDMFDRTTHEEYESCLADSFSQAADEEEELSTATKKLHT 763
            +++ Q+ E  + E +++ + L+ +      E++ + LA S    A +      ATK L  
Sbjct: 2578 QQRRQQEELLAEENQRLREQLQLL-----EEQHRAALAHSEEVTASQV----AATKTLPN 2628

Query: 764  HGDKQDKVKQKAFVEPYFKGDERETSLQNFPHIEVVRKKEERRKLLGHT 812
              D  D    +A  E  F G  R+ S Q      ++  +E +R   GHT
Sbjct: 2629 GRDALDGPAAEAEPEHSFDGLRRKVSAQRLQEAGILSAEELQRLAQGHT 2677


>gi|41322910 plectin 1 isoform 7 [Homo sapiens]
          Length = 4515

 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 44/140 (31%), Positives = 72/140 (51%), Gaps = 19/140 (13%)

Query: 27   LKECHDREVQGLQVKVTKLKQERILDAQR--LEEFF----TKNQQLREQQKVLHETIKVL 80
            L+E    +   L  K + L++ER ++ ++  LE+ F     K QQLRE+Q+   + ++  
Sbjct: 2453 LQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQE 2512

Query: 81   EDRLRAGLCD---RCAVTEEHMRKKQQEFENIRQQNLKLITELMNERNTLQEENKKLSEQ 137
              RL A + +   R    EE +R+KQ+E + + QQ          +   L EEN++L EQ
Sbjct: 2513 RQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQR-------RQQEELLAEENQRLREQ 2565

Query: 138  LQQKIENDQQHQAAELECEE 157
            LQ     ++QH+AA    EE
Sbjct: 2566 LQLL---EEQHRAALAHSEE 2582



 Score = 39.7 bits (91), Expect = 0.013
 Identities = 35/136 (25%), Positives = 70/136 (51%), Gaps = 8/136 (5%)

Query: 28   KECHDREVQGLQVKVTKLK---QERIL-DAQRLEE-FFTKNQQLREQQKVLHETIKVLED 82
            KE   +E + LQ+K  +++   QE++L + Q L++ F ++   L ++++ + +    LE 
Sbjct: 2427 KEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQ 2486

Query: 83   RLRAGLCDRCAVTEEHMRKKQQEFENIRQQNLKLITELMNERNTLQEENKKLSEQLQQKI 142
              +  +     + EE  R+ QQ+ E  RQ+ +  + E    ++  +E  ++  E+LQQ  
Sbjct: 2487 LFQDEVAKAQQLREEQQRQ-QQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQL- 2544

Query: 143  ENDQQHQAAELECEED 158
               Q+ Q  EL  EE+
Sbjct: 2545 -EQQRRQQEELLAEEN 2559



 Score = 32.0 bits (71), Expect = 2.6
 Identities = 27/109 (24%), Positives = 48/109 (44%), Gaps = 9/109 (8%)

Query: 704  KKQEQKGEKSSNEERKMNDSLEDMFDRTTHEEYESCLADSFSQAADEEEELSTATKKLHT 763
            +++ Q+ E  + E +++ + L+ +      E++ + LA S    A +      ATK L  
Sbjct: 2546 QQRRQQEELLAEENQRLREQLQLL-----EEQHRAALAHSEEVTASQV----AATKTLPN 2596

Query: 764  HGDKQDKVKQKAFVEPYFKGDERETSLQNFPHIEVVRKKEERRKLLGHT 812
              D  D    +A  E  F G  R+ S Q      ++  +E +R   GHT
Sbjct: 2597 GRDALDGPAAEAEPEHSFDGLRRKVSAQRLQEAGILSAEELQRLAQGHT 2645


>gi|41322916 plectin 1 isoform 6 [Homo sapiens]
          Length = 4684

 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 44/140 (31%), Positives = 72/140 (51%), Gaps = 19/140 (13%)

Query: 27   LKECHDREVQGLQVKVTKLKQERILDAQR--LEEFF----TKNQQLREQQKVLHETIKVL 80
            L+E    +   L  K + L++ER ++ ++  LE+ F     K QQLRE+Q+   + ++  
Sbjct: 2622 LQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQE 2681

Query: 81   EDRLRAGLCD---RCAVTEEHMRKKQQEFENIRQQNLKLITELMNERNTLQEENKKLSEQ 137
              RL A + +   R    EE +R+KQ+E + + QQ          +   L EEN++L EQ
Sbjct: 2682 RQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQR-------RQQEELLAEENQRLREQ 2734

Query: 138  LQQKIENDQQHQAAELECEE 157
            LQ     ++QH+AA    EE
Sbjct: 2735 LQLL---EEQHRAALAHSEE 2751



 Score = 39.7 bits (91), Expect = 0.013
 Identities = 35/136 (25%), Positives = 70/136 (51%), Gaps = 8/136 (5%)

Query: 28   KECHDREVQGLQVKVTKLK---QERIL-DAQRLEE-FFTKNQQLREQQKVLHETIKVLED 82
            KE   +E + LQ+K  +++   QE++L + Q L++ F ++   L ++++ + +    LE 
Sbjct: 2596 KEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQ 2655

Query: 83   RLRAGLCDRCAVTEEHMRKKQQEFENIRQQNLKLITELMNERNTLQEENKKLSEQLQQKI 142
              +  +     + EE  R+ QQ+ E  RQ+ +  + E    ++  +E  ++  E+LQQ  
Sbjct: 2656 LFQDEVAKAQQLREEQQRQ-QQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQL- 2713

Query: 143  ENDQQHQAAELECEED 158
               Q+ Q  EL  EE+
Sbjct: 2714 -EQQRRQQEELLAEEN 2728



 Score = 32.0 bits (71), Expect = 2.6
 Identities = 27/109 (24%), Positives = 48/109 (44%), Gaps = 9/109 (8%)

Query: 704  KKQEQKGEKSSNEERKMNDSLEDMFDRTTHEEYESCLADSFSQAADEEEELSTATKKLHT 763
            +++ Q+ E  + E +++ + L+ +      E++ + LA S    A +      ATK L  
Sbjct: 2715 QQRRQQEELLAEENQRLREQLQLL-----EEQHRAALAHSEEVTASQV----AATKTLPN 2765

Query: 764  HGDKQDKVKQKAFVEPYFKGDERETSLQNFPHIEVVRKKEERRKLLGHT 812
              D  D    +A  E  F G  R+ S Q      ++  +E +R   GHT
Sbjct: 2766 GRDALDGPAAEAEPEHSFDGLRRKVSAQRLQEAGILSAEELQRLAQGHT 2814


>gi|41322908 plectin 1 isoform 3 [Homo sapiens]
          Length = 4525

 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 44/140 (31%), Positives = 72/140 (51%), Gaps = 19/140 (13%)

Query: 27   LKECHDREVQGLQVKVTKLKQERILDAQR--LEEFF----TKNQQLREQQKVLHETIKVL 80
            L+E    +   L  K + L++ER ++ ++  LE+ F     K QQLRE+Q+   + ++  
Sbjct: 2463 LQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQE 2522

Query: 81   EDRLRAGLCD---RCAVTEEHMRKKQQEFENIRQQNLKLITELMNERNTLQEENKKLSEQ 137
              RL A + +   R    EE +R+KQ+E + + QQ          +   L EEN++L EQ
Sbjct: 2523 RQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQR-------RQQEELLAEENQRLREQ 2575

Query: 138  LQQKIENDQQHQAAELECEE 157
            LQ     ++QH+AA    EE
Sbjct: 2576 LQLL---EEQHRAALAHSEE 2592



 Score = 39.7 bits (91), Expect = 0.013
 Identities = 35/136 (25%), Positives = 70/136 (51%), Gaps = 8/136 (5%)

Query: 28   KECHDREVQGLQVKVTKLK---QERIL-DAQRLEE-FFTKNQQLREQQKVLHETIKVLED 82
            KE   +E + LQ+K  +++   QE++L + Q L++ F ++   L ++++ + +    LE 
Sbjct: 2437 KEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQ 2496

Query: 83   RLRAGLCDRCAVTEEHMRKKQQEFENIRQQNLKLITELMNERNTLQEENKKLSEQLQQKI 142
              +  +     + EE  R+ QQ+ E  RQ+ +  + E    ++  +E  ++  E+LQQ  
Sbjct: 2497 LFQDEVAKAQQLREEQQRQ-QQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQL- 2554

Query: 143  ENDQQHQAAELECEED 158
               Q+ Q  EL  EE+
Sbjct: 2555 -EQQRRQQEELLAEEN 2569



 Score = 32.0 bits (71), Expect = 2.6
 Identities = 27/109 (24%), Positives = 48/109 (44%), Gaps = 9/109 (8%)

Query: 704  KKQEQKGEKSSNEERKMNDSLEDMFDRTTHEEYESCLADSFSQAADEEEELSTATKKLHT 763
            +++ Q+ E  + E +++ + L+ +      E++ + LA S    A +      ATK L  
Sbjct: 2556 QQRRQQEELLAEENQRLREQLQLL-----EEQHRAALAHSEEVTASQV----AATKTLPN 2606

Query: 764  HGDKQDKVKQKAFVEPYFKGDERETSLQNFPHIEVVRKKEERRKLLGHT 812
              D  D    +A  E  F G  R+ S Q      ++  +E +R   GHT
Sbjct: 2607 GRDALDGPAAEAEPEHSFDGLRRKVSAQRLQEAGILSAEELQRLAQGHT 2655


>gi|41322912 plectin 1 isoform 2 [Homo sapiens]
          Length = 4533

 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 44/140 (31%), Positives = 72/140 (51%), Gaps = 19/140 (13%)

Query: 27   LKECHDREVQGLQVKVTKLKQERILDAQR--LEEFF----TKNQQLREQQKVLHETIKVL 80
            L+E    +   L  K + L++ER ++ ++  LE+ F     K QQLRE+Q+   + ++  
Sbjct: 2471 LQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQE 2530

Query: 81   EDRLRAGLCD---RCAVTEEHMRKKQQEFENIRQQNLKLITELMNERNTLQEENKKLSEQ 137
              RL A + +   R    EE +R+KQ+E + + QQ          +   L EEN++L EQ
Sbjct: 2531 RQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQR-------RQQEELLAEENQRLREQ 2583

Query: 138  LQQKIENDQQHQAAELECEE 157
            LQ     ++QH+AA    EE
Sbjct: 2584 LQLL---EEQHRAALAHSEE 2600



 Score = 39.7 bits (91), Expect = 0.013
 Identities = 35/136 (25%), Positives = 70/136 (51%), Gaps = 8/136 (5%)

Query: 28   KECHDREVQGLQVKVTKLK---QERIL-DAQRLEE-FFTKNQQLREQQKVLHETIKVLED 82
            KE   +E + LQ+K  +++   QE++L + Q L++ F ++   L ++++ + +    LE 
Sbjct: 2445 KEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQ 2504

Query: 83   RLRAGLCDRCAVTEEHMRKKQQEFENIRQQNLKLITELMNERNTLQEENKKLSEQLQQKI 142
              +  +     + EE  R+ QQ+ E  RQ+ +  + E    ++  +E  ++  E+LQQ  
Sbjct: 2505 LFQDEVAKAQQLREEQQRQ-QQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQL- 2562

Query: 143  ENDQQHQAAELECEED 158
               Q+ Q  EL  EE+
Sbjct: 2563 -EQQRRQQEELLAEEN 2577



 Score = 32.0 bits (71), Expect = 2.6
 Identities = 27/109 (24%), Positives = 48/109 (44%), Gaps = 9/109 (8%)

Query: 704  KKQEQKGEKSSNEERKMNDSLEDMFDRTTHEEYESCLADSFSQAADEEEELSTATKKLHT 763
            +++ Q+ E  + E +++ + L+ +      E++ + LA S    A +      ATK L  
Sbjct: 2564 QQRRQQEELLAEENQRLREQLQLL-----EEQHRAALAHSEEVTASQV----AATKTLPN 2614

Query: 764  HGDKQDKVKQKAFVEPYFKGDERETSLQNFPHIEVVRKKEERRKLLGHT 812
              D  D    +A  E  F G  R+ S Q      ++  +E +R   GHT
Sbjct: 2615 GRDALDGPAAEAEPEHSFDGLRRKVSAQRLQEAGILSAEELQRLAQGHT 2663


>gi|47607492 plectin 1 isoform 1 [Homo sapiens]
          Length = 4574

 Score = 52.8 bits (125), Expect = 1e-06
 Identities = 44/140 (31%), Positives = 72/140 (51%), Gaps = 19/140 (13%)

Query: 27   LKECHDREVQGLQVKVTKLKQERILDAQR--LEEFF----TKNQQLREQQKVLHETIKVL 80
            L+E    +   L  K + L++ER ++ ++  LE+ F     K QQLRE+Q+   + ++  
Sbjct: 2512 LQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQE 2571

Query: 81   EDRLRAGLCD---RCAVTEEHMRKKQQEFENIRQQNLKLITELMNERNTLQEENKKLSEQ 137
              RL A + +   R    EE +R+KQ+E + + QQ          +   L EEN++L EQ
Sbjct: 2572 RQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQR-------RQQEELLAEENQRLREQ 2624

Query: 138  LQQKIENDQQHQAAELECEE 157
            LQ     ++QH+AA    EE
Sbjct: 2625 LQLL---EEQHRAALAHSEE 2641



 Score = 39.7 bits (91), Expect = 0.013
 Identities = 35/136 (25%), Positives = 70/136 (51%), Gaps = 8/136 (5%)

Query: 28   KECHDREVQGLQVKVTKLK---QERIL-DAQRLEE-FFTKNQQLREQQKVLHETIKVLED 82
            KE   +E + LQ+K  +++   QE++L + Q L++ F ++   L ++++ + +    LE 
Sbjct: 2486 KEKLQQEAKLLQLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQRERFIEQEKAKLEQ 2545

Query: 83   RLRAGLCDRCAVTEEHMRKKQQEFENIRQQNLKLITELMNERNTLQEENKKLSEQLQQKI 142
              +  +     + EE  R+ QQ+ E  RQ+ +  + E    ++  +E  ++  E+LQQ  
Sbjct: 2546 LFQDEVAKAQQLREEQQRQ-QQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQL- 2603

Query: 143  ENDQQHQAAELECEED 158
               Q+ Q  EL  EE+
Sbjct: 2604 -EQQRRQQEELLAEEN 2618



 Score = 32.0 bits (71), Expect = 2.6
 Identities = 27/109 (24%), Positives = 48/109 (44%), Gaps = 9/109 (8%)

Query: 704  KKQEQKGEKSSNEERKMNDSLEDMFDRTTHEEYESCLADSFSQAADEEEELSTATKKLHT 763
            +++ Q+ E  + E +++ + L+ +      E++ + LA S    A +      ATK L  
Sbjct: 2605 QQRRQQEELLAEENQRLREQLQLL-----EEQHRAALAHSEEVTASQV----AATKTLPN 2655

Query: 764  HGDKQDKVKQKAFVEPYFKGDERETSLQNFPHIEVVRKKEERRKLLGHT 812
              D  D    +A  E  F G  R+ S Q      ++  +E +R   GHT
Sbjct: 2656 GRDALDGPAAEAEPEHSFDGLRRKVSAQRLQEAGILSAEELQRLAQGHT 2704


>gi|22538393 A-kinase anchor protein 9 isoform 3 [Homo sapiens]
          Length = 3899

 Score = 48.9 bits (115), Expect = 2e-05
 Identities = 168/839 (20%), Positives = 326/839 (38%), Gaps = 122/839 (14%)

Query: 28   KECHDREVQGLQVKVTKLKQERILDAQRLEEFFTKNQQLRE------------------- 68
            K   +R++Q     + +L+QE +  + RL+E   + QQ++E                   
Sbjct: 1931 KTLFERQIQEKTDIIDRLEQELLCASNRLQELEAEQQQIQEERELLSRQKEAMKAEAGPV 1990

Query: 69   QQKVLHETIKVLEDRLRAGLCDRCAVTEEHMRKKQQEFENIRQQNLKLITELMNERNT-- 126
            +Q++L ET K+++++L    C    V ++ ++K+ +  E   ++ +    EL  E+NT  
Sbjct: 1991 EQQLLQETEKLMKEKLEV-QCQAEKVRDD-LQKQVKALEIDVEEQVSRFIELEQEKNTEL 2048

Query: 127  --LQEENKKLSEQLQQKIENDQQHQAAELECEEDVI-PDSPITAFSFSGVNRLRRKENPH 183
              L+++N+ L +QL +K+      QA + E E DV   +          V R +      
Sbjct: 2049 MDLRQQNQALEKQL-EKMRKFLDEQAIDREHERDVFQQEIQKLEQQLKVVPRFQPISEHQ 2107

Query: 184  VRYIEQ--THTKLEHSVCANEMRKVSKSSTHPQHNPNENEILVADTYDQSQSPMAKAHGT 241
             R +EQ   H K +   C+  +    +     Q    E E L     +  Q+ + +    
Sbjct: 2108 TREVEQLANHLKEKTDKCSELLLSKEQLQRDIQERNEEIEKLEFRVRELEQALLVE---- 2163

Query: 242  SSYTPDKSSFNLATVVAETLGLGVQEESE------TQGPMSPLGDELYHCLEGNHKKQPF 295
                 D+  F       E L L VQ ++E       +  ++ L ++L    E    K   
Sbjct: 2164 -----DRKHFGAVEAKPE-LSLEVQLQAERDAIDRKEKEITNLEEQLEQFREELENKNE- 2216

Query: 296  EESTRNTEDSLRFSDSTSKTPPQEELPTRVSSPVFGATSSIKSGLDLNTSLSPSLLQPGK 355
            E    + +  ++  +ST++    E+        +     +IK    ++T     L     
Sbjct: 2217 EVQQLHMQLEIQKKESTTRLQELEQENKLFKDDMEKLGLAIKESDAMSTQDQHVLF---- 2272

Query: 356  KKHLKTLPFSNTCISRLEKTRSKSEDSALFTHHSLGSEVNKIIIQSSNKQILINKNISES 415
             K  + +      I +L +  +K +     T  +   E    +I+    QI    +  E 
Sbjct: 2273 GKFAQIIQEKEVEIDQLNEQVTKLQQQLKITTDNKVIEEKNELIRDLETQIECLMSDQEC 2332

Query: 416  LGEQNRTEYGKDSN--TDKHLEPLKSLGGRTSKRKKTEEESEHEVSCPQASFDKENAFPF 473
            + ++NR E  +  N   +K  + L ++G +TS    +  E   E    +   D   A   
Sbjct: 2333 V-KRNREEEIEQLNEVIEKLQQELANIGQKTSMNAHSLSE---EADSLKHQLDVVIAEKL 2388

Query: 474  PMDNQF-SMNGDCVMDKPLDLSDRFSAIQRQEKSQGSETSKNKFRQVTLYEALKTIPKGF 532
             ++ Q  + N +    K +     F      + +Q ++   +  R+    E +++IP+  
Sbjct: 2389 ALEQQVETANEEMTFMKNVLKETNF------KMNQLTQELFSLKRERESVEKIQSIPE-- 2440

Query: 533  SSSRKASDGNCTLPKDSPGEPCSQECIILQPLNKCSPDNKPSLQIKEENAVFKIPLRPRE 592
            +S   A D    L KD P      E ++ +   K S +N+   +  EEN    I      
Sbjct: 2441 NSVNVAID---HLSKDKP----ELEVVLTEDALK-SLENQTYFKSFEENGKGSIINLETR 2492

Query: 593  SLETENV--------------LDDIKSAGSHEPIKIQTR--------SDHGGCELASVLQ 630
             L+ E+               + D++  G  E   +Q +         +     L S +Q
Sbjct: 2493 LLQLESTVSAKDLELTQCYKQIKDMQEQGQFETEMLQKKIVNLQKIVEEKVAAALVSQIQ 2552

Query: 631  LNPCRTGKIKSLQNNQDVSFENIQWSIDPGADLSQYKM--DVTVIDTKDGSQSKLGGETV 688
            L   +    K  Q+NQ +S E  + +I     L + ++  D++ +  +    S+L  + V
Sbjct: 2553 LEAVQE-YAKFCQDNQTISSEPERTNIQNLNQLREDELGSDISALTLR---ISELESQVV 2608

Query: 689  DMDCTLV---------------SETVLLKMKKQEQKGEKSSNEERKMNDSLEDMFDRTTH 733
            +M  +L+                E  LL+++K  +  EK   E+ K     +    +TT 
Sbjct: 2609 EMHTSLILEKEQVEIAEKNVLEKEKKLLELQKLLEGNEKKQREKEKKRSPQDVEVLKTTT 2668

Query: 734  EEYESCLADSFSQAADEEEELSTATK-KLHTHGDKQDKVKQKAFVEPYFKGDERETSLQ 791
            E + S     F    +     S ATK +L ++ +K +K++++  V+     +   TSLQ
Sbjct: 2669 ELFHSNEESGFFNELEALRAESVATKAELASYKEKAEKLQEELLVK-----ETNMTSLQ 2722



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 45/187 (24%), Positives = 87/187 (46%), Gaps = 20/187 (10%)

Query: 26  KLKECHDREVQGLQVKVTKLKQERILDAQRLEEFFTK----NQQLREQQKVLHETIKV-- 79
           K K   ++EVQ LQ+K   L+++       L+E F +    N  L++++K L + +K+  
Sbjct: 736 KEKGTLEQEVQELQLKTELLEKQMKEKENDLQEKFAQLEAENSILKDEKKTLEDMLKIHT 795

Query: 80  ---LEDRL----RAGLCDRCAVTEEHMRKKQQEFENIRQQNLKLITELMNERNTLQEENK 132
               E+RL          + +V E+ +    +E E+++QQ ++L  E+  +RNT     K
Sbjct: 796 PVSQEERLIFLDSIKSKSKDSVWEKEIEILIEENEDLKQQCIQLNEEIEKQRNTFSFAEK 855

Query: 133 KLSEQLQQKIENDQQHQAAELECEEDVIPDSPITAFSFSGVNRLRR-KENPHVRYIEQTH 191
                 Q+     Q+  A  L+ ++D+          +   ++L+   E  H++ I  T 
Sbjct: 856 NFEVNYQEL----QEEYACLLKVKDDLEDSKNKQELEYK--SKLKALNEELHLQRINPTT 909

Query: 192 TKLEHSV 198
            K++ SV
Sbjct: 910 VKMKSSV 916



 Score = 39.3 bits (90), Expect = 0.017
 Identities = 32/115 (27%), Positives = 62/115 (53%), Gaps = 4/115 (3%)

Query: 53  AQRLEEF-FTKNQQLREQQKVLHETIKVLEDRLRAGLCDRCAVTEEHMRKKQQEFENIRQ 111
           +Q++E   F K+  + +Q +++ E  K L+D  ++ +  +       + + Q+E E +RQ
Sbjct: 675 SQKIETMQFEKDNLITKQNQLILEISK-LKDLQQSLVNSKSEEMTLQINELQKEIEILRQ 733

Query: 112 QNLKLITELMNERNTLQEENKKLSEQLQQKIENDQQHQAAELECEEDVIPDSPIT 166
           +  +  T L  E   LQ + + L +Q+++K END Q + A+LE E  ++ D   T
Sbjct: 734 EEKEKGT-LEQEVQELQLKTELLEKQMKEK-ENDLQEKFAQLEAENSILKDEKKT 786



 Score = 35.4 bits (80), Expect = 0.24
 Identities = 29/109 (26%), Positives = 52/109 (47%), Gaps = 16/109 (14%)

Query: 57   EEFFTKNQQLREQQKVLHETIKVL-----------EDRLRAGLCDRCAVTEEHMRKKQQE 105
            EE F+K++    +Q + H+ I V            E++L     +     +EH    QQ 
Sbjct: 1550 EEMFSKDKTFIVRQSI-HDEISVSSMDASRQLMLNEEQLEDMRQELVRQYQEH----QQA 1604

Query: 106  FENIRQQNLKLITELMNERNTLQEENKKLSEQLQQKIENDQQHQAAELE 154
             E +RQ +++ +     ++  LQEE K+L+ QL Q+   D ++  +E E
Sbjct: 1605 TELLRQAHMRQMERQREDQEQLQEEIKRLNRQLAQRSSIDNENLVSERE 1653



 Score = 31.6 bits (70), Expect = 3.5
 Identities = 29/133 (21%), Positives = 65/133 (48%), Gaps = 9/133 (6%)

Query: 15   DTSSDFKDLWTKLKECHDREVQGLQVKVTKL----KQERILDAQ--RLEEFFTKNQQLRE 68
            D     K L   ++E   R ++  Q K T+L    +Q + L+ Q  ++ +F  +    RE
Sbjct: 2018 DLQKQVKALEIDVEEQVSRFIELEQEKNTELMDLRQQNQALEKQLEKMRKFLDEQAIDRE 2077

Query: 69   QQK-VLHETIKVLEDRLRAGLCDRCAVTEEHMRKKQQEFENIRQQNLKLITELMNERNTL 127
             ++ V  + I+ LE +L+  +  R     EH  ++ ++  N  ++     +EL+  +  L
Sbjct: 2078 HERDVFQQEIQKLEQQLK--VVPRFQPISEHQTREVEQLANHLKEKTDKCSELLLSKEQL 2135

Query: 128  QEENKKLSEQLQQ 140
            Q + ++ +E++++
Sbjct: 2136 QRDIQERNEEIEK 2148



 Score = 31.2 bits (69), Expect = 4.5
 Identities = 41/218 (18%), Positives = 91/218 (41%), Gaps = 48/218 (22%)

Query: 32  DREVQGLQVKVTKLKQERILDAQRLEEFFTKNQQLREQ------------QKVLHETIKV 79
           ++E++ +++++T  KQ+    ++ +++     ++L+++            Q++  ET + 
Sbjct: 370 NQEIKNMKLELTNSKQKERQSSEEIKQLMGTVEELQKRNHKDSQFETDIVQRMEQETQRK 429

Query: 80  LEDRLRAGLCD----------------RCAVTEEHMRKKQQEFEN---------IRQQNL 114
           LE +LRA L +                  A  EE   + + E EN         + +  +
Sbjct: 430 LE-QLRAELDEMYGQQIVQMKQELIRQHMAQMEEMKTRHKGEMENALRSYSNITVNEDQI 488

Query: 115 KLITELMNERNTLQEENKKLSEQLQQKIENDQQHQAAELECEEDVIPDSPITAFSFSGVN 174
           KL+   +NE N   ++     E+L++++    + + A     ED++ +    +FS   + 
Sbjct: 489 KLMNVAINELNIKLQDTNSQKEKLKEELGLILEEKCALQRQLEDLVEE---LSFSREQIQ 545

Query: 175 RLRRKENPHVRYIEQTHTKLE-------HSVCANEMRK 205
           R R+        + + H  L          V A+E RK
Sbjct: 546 RARQTIAEQESKLNEAHKSLSTVEDLKAEIVSASESRK 583



 Score = 31.2 bits (69), Expect = 4.5
 Identities = 22/74 (29%), Positives = 36/74 (48%), Gaps = 14/74 (18%)

Query: 96   EEHMRKKQQEFENIRQQNLKLITELMNERNTLQE----ENKKLSEQ----------LQQK 141
            EE++ K++ EF +I  Q   L    +N ++ L      E  KL EQ          LQQ+
Sbjct: 1294 EENLPKEETEFLSIHSQMTNLEDIDVNHKSKLSSLQDLEKTKLEEQVQELESLISSLQQQ 1353

Query: 142  IENDQQHQAAELEC 155
            ++  +Q+  AE+ C
Sbjct: 1354 LKETEQNYEAEIHC 1367


>gi|50897852 coiled-coil domain containing 88A isoform 2 [Homo
           sapiens]
          Length = 1843

 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 54/203 (26%), Positives = 91/203 (44%), Gaps = 11/203 (5%)

Query: 40  VKVTKLKQERILDAQRLE--EFF-TKNQQLREQQKVLHETIKVLEDRLRA--GLCDRCAV 94
           V+V KL+ E     +RL   EF+  + ++L+E  +VL ET  +LED+L       D+   
Sbjct: 320 VRVDKLESEVSRYKERLHDIEFYKARVEELKEDNQVLLETKTMLEDQLEGTRARSDKLHE 379

Query: 95  TEE---HMRKKQQEFENIRQQNLKLITELMNERNTLQEENKK-LSEQLQQKIENDQQHQA 150
            E+    ++ K  + E  R  + K I ELM E  TL+   K+ + E L    E +Q  + 
Sbjct: 380 LEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQSMDESLHLGWELEQISRT 439

Query: 151 AELECEEDVIPDSPITAFSFSGVNRLRRKENPHVRYIEQTHTKLEHSVCANEMRKVSKSS 210
           +EL           +   + S + +L  +     + +E+  T ++ SV  N   K+ K  
Sbjct: 440 SELSEAPQKSLGHEVNELTSSRLLKLEMENQSLTKTVEELRTTVD-SVEGN-ASKILKME 497

Query: 211 THPQHNPNENEILVADTYDQSQS 233
              Q    + EIL  +   + QS
Sbjct: 498 KENQRLSKKVEILENEIVQEKQS 520



 Score = 38.9 bits (89), Expect = 0.022
 Identities = 38/127 (29%), Positives = 63/127 (49%), Gaps = 9/127 (7%)

Query: 41   KVTKLKQERILDAQ-RLEEFFTKNQQLREQQKVL---HETIKVLEDRLRAGLCDRCAVTE 96
            K  ++K+E+I   + RLEE    NQQLR++ K +   +E +K  +D  R          E
Sbjct: 967  KSLEIKEEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEERMVQSSPPISGE 1026

Query: 97   EHMRKKQQEFENIRQQNLKLITELMN-ERN--TLQEENKKLSEQLQQKIENDQQHQAAEL 153
            ++  K ++E +   ++ LK+   L+  ERN  TLQ E + L  QL+Q    +   QA  L
Sbjct: 1027 DN--KWERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQIL 1084

Query: 154  ECEEDVI 160
              +   +
Sbjct: 1085 ALQRQTV 1091



 Score = 34.3 bits (77), Expect = 0.53
 Identities = 45/230 (19%), Positives = 101/230 (43%), Gaps = 25/230 (10%)

Query: 31  HDREVQGLQVKVT--KLKQERILDAQRLEEFFTKNQQLREQQKV-LHETIKV---LEDRL 84
           H+ E + LQ+K     ++ ER +D +++EE   +N  L   QK  + E++ +   LE   
Sbjct: 378 HELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQSMDESLHLGWELEQIS 437

Query: 85  RAGLCDRCA----------VTEEHMRKKQQEFENIRQQNLKLITELMNERNT------LQ 128
           R                  +T   + K + E +++ +   +L T + +          ++
Sbjct: 438 RTSELSEAPQKSLGHEVNELTSSRLLKLEMENQSLTKTVEELRTTVDSVEGNASKILKME 497

Query: 129 EENKKLSEQLQQKIENDQQHQAAELECEEDVIPD-SPITAFSFSGVNRLRRKENPHVRYI 187
           +EN++LS++++  +EN+   +   L+  +++  D     A     +  LR      ++ +
Sbjct: 498 KENQRLSKKVEI-LENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKIL 556

Query: 188 EQTHTKLEHSVCANEMRKVSKSSTHPQHNPNENEILVADTYDQSQSPMAK 237
           EQ +  L  +V +   R    +    +    EN+IL  ++  ++ S ++K
Sbjct: 557 EQENEHLNQTVSSLRQRSQISAEARVKDIEKENKIL-HESIKETSSKLSK 605



 Score = 33.9 bits (76), Expect = 0.70
 Identities = 44/225 (19%), Positives = 98/225 (43%), Gaps = 14/225 (6%)

Query: 2   NISGSSCGSPNSADTSSDFKDLWTKLKECHDREVQGLQVKVTKLKQERILDAQRLEEFFT 61
           N+    C S   A    + K+L ++ ++      +GL++     K+   L+    +    
Sbjct: 709 NVESLKCASMKMAQLQLENKELESEKEQLK----KGLELLKASFKKTERLEVS-YQGLDI 763

Query: 62  KNQQLREQQKVLHETIKVLEDRLRAGLCDRCAVTE--EHMRKKQQEFENIRQQNLKL--- 116
           +NQ+L++  +  ++ I+ LE  L+    +   + +  E ++   +  E + ++N  L   
Sbjct: 764 ENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQE 823

Query: 117 ITELMNERNTLQEENKKLSEQLQQKIENDQQH--QAAELECEEDVIPDSPITAFSFSGVN 174
            ++L  ++  L++ENK+L +Q + K    +++  +   LE E   +    I  +  S V 
Sbjct: 824 TSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTL-SKEIGIYKESCV- 881

Query: 175 RLRRKENPHVRYIEQTHTKLEHSVCANEMRKVSKSSTHPQHNPNE 219
           RL+  E  +   +++    ++  V   E     K  T   +N  E
Sbjct: 882 RLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLE 926



 Score = 32.7 bits (73), Expect = 1.6
 Identities = 28/147 (19%), Positives = 68/147 (46%), Gaps = 3/147 (2%)

Query: 20   FKDLWTKLKECHDREVQGLQVKVTKLKQERILDAQRLEEFFTKNQQLREQQKVLHETIKV 79
            +K+   +LKE      + ++     +K    L    + E     Q   + +K+ HE  K+
Sbjct: 876  YKESCVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKI 935

Query: 80   LEDRLRAGLCDRCAVTEEHMRKKQQEFENIRQQNLKLITELMNERNTLQEENKKLSEQLQ 139
              ++ R  L D  +  +   +  + + E+  +++L++  E +       EE+   ++QL+
Sbjct: 936  GLNKERL-LHDEQSTDDSRYKLLESKLESTLKKSLEIKEEKIAALEARLEESTNYNQQLR 994

Query: 140  QKIENDQQHQAA--ELECEEDVIPDSP 164
            Q+++  +++  A  + + EE ++  SP
Sbjct: 995  QELKTVKKNYEALKQRQDEERMVQSSP 1021


>gi|208022632 coiled-coil domain containing 88A isoform 1 [Homo
           sapiens]
          Length = 1870

 Score = 46.2 bits (108), Expect = 1e-04
 Identities = 54/203 (26%), Positives = 91/203 (44%), Gaps = 11/203 (5%)

Query: 40  VKVTKLKQERILDAQRLE--EFF-TKNQQLREQQKVLHETIKVLEDRLRA--GLCDRCAV 94
           V+V KL+ E     +RL   EF+  + ++L+E  +VL ET  +LED+L       D+   
Sbjct: 320 VRVDKLESEVSRYKERLHDIEFYKARVEELKEDNQVLLETKTMLEDQLEGTRARSDKLHE 379

Query: 95  TEE---HMRKKQQEFENIRQQNLKLITELMNERNTLQEENKK-LSEQLQQKIENDQQHQA 150
            E+    ++ K  + E  R  + K I ELM E  TL+   K+ + E L    E +Q  + 
Sbjct: 380 LEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQSMDESLHLGWELEQISRT 439

Query: 151 AELECEEDVIPDSPITAFSFSGVNRLRRKENPHVRYIEQTHTKLEHSVCANEMRKVSKSS 210
           +EL           +   + S + +L  +     + +E+  T ++ SV  N   K+ K  
Sbjct: 440 SELSEAPQKSLGHEVNELTSSRLLKLEMENQSLTKTVEELRTTVD-SVEGN-ASKILKME 497

Query: 211 THPQHNPNENEILVADTYDQSQS 233
              Q    + EIL  +   + QS
Sbjct: 498 KENQRLSKKVEILENEIVQEKQS 520



 Score = 38.9 bits (89), Expect = 0.022
 Identities = 38/127 (29%), Positives = 63/127 (49%), Gaps = 9/127 (7%)

Query: 41   KVTKLKQERILDAQ-RLEEFFTKNQQLREQQKVL---HETIKVLEDRLRAGLCDRCAVTE 96
            K  ++K+E+I   + RLEE    NQQLR++ K +   +E +K  +D  R          E
Sbjct: 966  KSLEIKEEKIAALEARLEESTNYNQQLRQELKTVKKNYEALKQRQDEERMVQSSPPISGE 1025

Query: 97   EHMRKKQQEFENIRQQNLKLITELMN-ERN--TLQEENKKLSEQLQQKIENDQQHQAAEL 153
            ++  K ++E +   ++ LK+   L+  ERN  TLQ E + L  QL+Q    +   QA  L
Sbjct: 1026 DN--KWERESQETTRELLKVKDRLIEVERNNATLQAEKQALKTQLKQLETQNNNLQAQIL 1083

Query: 154  ECEEDVI 160
              +   +
Sbjct: 1084 ALQRQTV 1090



 Score = 34.3 bits (77), Expect = 0.53
 Identities = 45/230 (19%), Positives = 101/230 (43%), Gaps = 25/230 (10%)

Query: 31  HDREVQGLQVKVT--KLKQERILDAQRLEEFFTKNQQLREQQKV-LHETIKV---LEDRL 84
           H+ E + LQ+K     ++ ER +D +++EE   +N  L   QK  + E++ +   LE   
Sbjct: 378 HELEKENLQLKAKLHDMEMERDMDRKKIEELMEENMTLEMAQKQSMDESLHLGWELEQIS 437

Query: 85  RAGLCDRCA----------VTEEHMRKKQQEFENIRQQNLKLITELMNERNT------LQ 128
           R                  +T   + K + E +++ +   +L T + +          ++
Sbjct: 438 RTSELSEAPQKSLGHEVNELTSSRLLKLEMENQSLTKTVEELRTTVDSVEGNASKILKME 497

Query: 129 EENKKLSEQLQQKIENDQQHQAAELECEEDVIPD-SPITAFSFSGVNRLRRKENPHVRYI 187
           +EN++LS++++  +EN+   +   L+  +++  D     A     +  LR      ++ +
Sbjct: 498 KENQRLSKKVEI-LENEIVQEKQSLQNCQNLSKDLMKEKAQLEKTIETLRENSERQIKIL 556

Query: 188 EQTHTKLEHSVCANEMRKVSKSSTHPQHNPNENEILVADTYDQSQSPMAK 237
           EQ +  L  +V +   R    +    +    EN+IL  ++  ++ S ++K
Sbjct: 557 EQENEHLNQTVSSLRQRSQISAEARVKDIEKENKIL-HESIKETSSKLSK 605



 Score = 33.9 bits (76), Expect = 0.70
 Identities = 44/225 (19%), Positives = 98/225 (43%), Gaps = 14/225 (6%)

Query: 2   NISGSSCGSPNSADTSSDFKDLWTKLKECHDREVQGLQVKVTKLKQERILDAQRLEEFFT 61
           N+    C S   A    + K+L ++ ++      +GL++     K+   L+    +    
Sbjct: 709 NVESLKCASMKMAQLQLENKELESEKEQLK----KGLELLKASFKKTERLEVS-YQGLDI 763

Query: 62  KNQQLREQQKVLHETIKVLEDRLRAGLCDRCAVTE--EHMRKKQQEFENIRQQNLKL--- 116
           +NQ+L++  +  ++ I+ LE  L+    +   + +  E ++   +  E + ++N  L   
Sbjct: 764 ENQRLQKTLENSNKKIQQLESELQDLEMENQTLQKNLEELKISSKRLEQLEKENKSLEQE 823

Query: 117 ITELMNERNTLQEENKKLSEQLQQKIENDQQH--QAAELECEEDVIPDSPITAFSFSGVN 174
            ++L  ++  L++ENK+L +Q + K    +++  +   LE E   +    I  +  S V 
Sbjct: 824 TSQLEKDKKQLEKENKRLRQQAEIKDTTLEENNVKIGNLEKENKTL-SKEIGIYKESCV- 881

Query: 175 RLRRKENPHVRYIEQTHTKLEHSVCANEMRKVSKSSTHPQHNPNE 219
           RL+  E  +   +++    ++  V   E     K  T   +N  E
Sbjct: 882 RLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLE 926



 Score = 31.2 bits (69), Expect = 4.5
 Identities = 29/147 (19%), Positives = 70/147 (47%), Gaps = 4/147 (2%)

Query: 20   FKDLWTKLKECHDREVQGLQVKVTKLKQERILDAQRLEEFFTKNQQLREQQKVLHETIKV 79
            +K+   +LKE      + ++     +K    L    + E     Q   + +K+ HE  K+
Sbjct: 876  YKESCVRLKELEKENKELVKRATIDIKTLVTLREDLVSEKLKTQQMNNDLEKLTHELEKI 935

Query: 80   LEDRLRAGLCDRCAVTEEHMRKKQQEFENIRQQNLKLITELMNERNTLQEENKKLSEQLQ 139
              ++ R  L D  + T++  +  + + E+  +++L++  E +       EE+   ++QL+
Sbjct: 936  GLNKERL-LHDEQS-TDDRYKLLESKLESTLKKSLEIKEEKIAALEARLEESTNYNQQLR 993

Query: 140  QKIENDQQHQAA--ELECEEDVIPDSP 164
            Q+++  +++  A  + + EE ++  SP
Sbjct: 994  QELKTVKKNYEALKQRQDEERMVQSSP 1020


>gi|94538359 golgi autoantigen, golgin subfamily a, 6B [Homo
           sapiens]
          Length = 693

 Score = 45.4 bits (106), Expect = 2e-04
 Identities = 51/221 (23%), Positives = 91/221 (41%), Gaps = 27/221 (12%)

Query: 36  QGLQVKVTKLKQERILDAQRLEEFFTKNQQLREQQKVLH---ETIKVLEDRLRAGLCDRC 92
           Q LQ +   L+++ +   +  E    +N++LREQQK L    E ++  E RLR       
Sbjct: 337 QRLQEQEEMLREQEVQRVREQERLCEQNERLREQQKTLQEQGERLRKQEQRLRK------ 390

Query: 93  AVTEEHMRKKQQEFENIRQQNLKLITELMNERNTLQEENKKLSEQLQQKIENDQQHQAAE 152
              EE +RK+++  +   ++       L  +   LQ++ ++L+     K++     Q AE
Sbjct: 391 --QEERLRKEEERLQKQEKRLWDQEERLWKKEERLQKQEERLALSQNHKLDK----QLAE 444

Query: 153 LECEEDVIPDSPITAFSF-SGVNRLRRK-ENPHVRYIEQTHTKLEHSVCANEMRKVSKSS 210
            +C  + + +   +A      V  L+ K +  H+    Q + +LE  +    +       
Sbjct: 445 PQCSFEDLNNEKKSALQLEQQVKELQEKLDEEHLEAASQQNQQLETQLSLVALPGEGDGG 504

Query: 211 TH--------PQHNPNENEILVADTYDQS--QSPMAKAHGT 241
            H        P+  PN  E L +     S    P  KA GT
Sbjct: 505 QHLDSEEEEAPRPTPNIPEDLESREATSSFMDLPKEKADGT 545



 Score = 41.6 bits (96), Expect = 0.003
 Identities = 44/183 (24%), Positives = 89/183 (48%), Gaps = 15/183 (8%)

Query: 33  REVQGLQVKV-TKLKQERILDAQRLEEFFTKNQQLREQQKVLHETIKVLEDRLRAGLCDR 91
           +EV+GL+ K+ ++++  + L     E+     Q+L+EQ+++L E  +V   R +  LC++
Sbjct: 309 QEVEGLEGKLQSQVENNQALSLLSKEQ----KQRLQEQEEMLREQ-EVQRVREQERLCEQ 363

Query: 92  CAVTEEHMRKKQQEFENIRQQNLKLITE---LMNERNTLQEENKKLSEQLQQ--KIENDQ 146
                E  +  Q++ E +R+Q  +L  +   L  E   LQ++ K+L +Q ++  K E   
Sbjct: 364 NERLREQQKTLQEQGERLRKQEQRLRKQEERLRKEEERLQKQEKRLWDQEERLWKKEERL 423

Query: 147 QHQAAELECEEDVIPDSPIT--AFSFSGVNRLRRKENPHVRYIEQTHTKL--EHSVCANE 202
           Q Q   L   ++   D  +     SF  +N  ++      + +++   KL  EH   A++
Sbjct: 424 QKQEERLALSQNHKLDKQLAEPQCSFEDLNNEKKSALQLEQQVKELQEKLDEEHLEAASQ 483

Query: 203 MRK 205
             +
Sbjct: 484 QNQ 486



 Score = 39.7 bits (91), Expect = 0.013
 Identities = 61/286 (21%), Positives = 119/286 (41%), Gaps = 51/286 (17%)

Query: 38  LQVKVTKLKQERILDAQRLEEFFT-----KNQ-----------------QLREQQKVLHE 75
           + V+   LK+E+  D  R++E        KNQ                 QL+++ K L +
Sbjct: 250 MSVEARTLKEEKKRDIHRIQELERSLSELKNQMAKPPSLAPPAVTSVVEQLQDEAKHLRQ 309

Query: 76  TIKVLEDRLRAGLCDRCA---VTEEHMRKKQQEFENIRQQNLKLITE---LMNERNTLQE 129
            ++ LE +L++ + +  A   +++E  ++ Q++ E +R+Q ++ + E   L  +   L+E
Sbjct: 310 EVEGLEGKLQSQVENNQALSLLSKEQKQRLQEQEEMLREQEVQRVREQERLCEQNERLRE 369

Query: 130 ENKKLSEQLQ--QKIENDQQHQAAELECEEDVIPDSPITAFSFSGVNRLRRKENPHVRYI 187
           + K L EQ +  +K E   + Q   L  EE+ +       +      RL +K        
Sbjct: 370 QQKTLQEQGERLRKQEQRLRKQEERLRKEEERLQKQEKRLWDQE--ERLWKK-------- 419

Query: 188 EQTHTKLEHSVCANEMRKVSKSSTHPQ------HNPNENEILVADTYDQSQSPMAKAH-G 240
           E+   K E  +  ++  K+ K    PQ      +N  ++ + +     + Q  + + H  
Sbjct: 420 EERLQKQEERLALSQNHKLDKQLAEPQCSFEDLNNEKKSALQLEQQVKELQEKLDEEHLE 479

Query: 241 TSSYTPDKSSFNLATVVAETLGLGVQ----EESETQGPMSPLGDEL 282
            +S    +    L+ V     G G Q    EE E   P   + ++L
Sbjct: 480 AASQQNQQLETQLSLVALPGEGDGGQHLDSEEEEAPRPTPNIPEDL 525


>gi|55770888 early endosome antigen 1, 162kD [Homo sapiens]
          Length = 1411

 Score = 45.1 bits (105), Expect = 3e-04
 Identities = 153/797 (19%), Positives = 308/797 (38%), Gaps = 146/797 (18%)

Query: 32   DREVQGLQVKVTKLKQ---ERILDAQRLEEFFTKNQQLREQQKVLHETIKVLEDRLRAGL 88
            +++V  LQ+K+++L++   E++ ++  L+    K +Q  ++Q+ L ++      +LR   
Sbjct: 452  EQQVADLQLKLSRLEEQLKEKVTNSTELQHQLDKTKQQHQEQQALQQSTTA---KLREAQ 508

Query: 89   CDRCAVTEEHMRKKQ--QEFENIRQQNLKLITELMNER-----------------NTLQE 129
             D   V  +   K Q  Q  E + Q++ + I+ L  ER                 N LQE
Sbjct: 509  NDLEQVLRQIGDKDQKIQNLEALLQKSKENISLLEKEREDLYAKIQAGEGETAVLNQLQE 568

Query: 130  ENKKLSEQLQQKIENDQQHQAAELECEEDVIPDSPITAFSFSGVNRLRRKENPHVRYIEQ 189
            +N  L EQ+ Q  E  +    +  + +E+              ++   +++  H+R  + 
Sbjct: 569  KNHTLQEQVTQLTEKLKNQSESHKQAQEN--------------LHDQVQEQKAHLRAAQD 614

Query: 190  THTKLEHSVCANEMRKVSKSSTHPQHNPNENEILVADTYDQSQSPMAKAHGTSSYTPDKS 249
                LE SV  NE+        + Q N ++ ++   D   ++++ +  +   ++ T  ++
Sbjct: 615  RVLSLETSV--NEL--------NSQLNESKEKVSQLDIQIKAKTELLLS-AEAAKTAQRA 663

Query: 250  SFNLATVVAETLGLGVQEE-----SETQGPMSPLGDELYHCLEGNHKKQPFEESTRNTED 304
                    A+      Q+E     ++     + L D+  HC +     + ++E   + E 
Sbjct: 664  DLQNHLDTAQNALQDKQQELNKITTQLDQVTAKLQDKQEHCSQLESHLKEYKEKYLSLEQ 723

Query: 305  SLRFSDSTSKTPPQEELPTRVSSPVFGATSSIKSGLDLNTSLSPSLLQPGKKKHLKTLPF 364
                 +   K    + L  + S     A   ++    LNT L     +  K+  ++    
Sbjct: 724  KTEELEGQIKKLEADSLEVKASKE--QALQDLQQQRQLNTDLELRATELSKQLEMEKEIV 781

Query: 365  SNTCISRLEKTRSKSEDSALFTHHSLGSEVNKIIIQSSNKQILINKNISESLGEQNRTEY 424
            S+T   RL+  + KSE        +L S   K+  Q   KQIL  K   E+L ++ + ++
Sbjct: 782  SST---RLD-LQKKSE--------ALESIKQKLTKQEEEKQIL--KQDFETLSQETKIQH 827

Query: 425  GKDSNTDKHLEPLKSLGGRTSKRKKTEEESEHEVSCPQASFDKENAFPFPMDNQFSMNGD 484
             + +N       +++      K K  +E    E+S  +    K +       ++F     
Sbjct: 828  EELNNR------IQTTVTELQKVKMEKEALMTELSTVKDKLSKVSDSLKNSKSEFEKENQ 881

Query: 485  CVMDKPLDLSDRFSAIQRQEKSQGSETSKNKFRQVTLYEALKTIPKGFSSSRKASDGNCT 544
                  LDL      ++ Q + Q   T K +          K + K     ++AS     
Sbjct: 882  KGKAAILDLEKTCKELKHQLQVQMENTLKEQ----------KELKKSLEKEKEASH-QLK 930

Query: 545  LPKDSPGEPCSQECIILQPLNKCSPDNKPSLQIKEENAVFKIPLRPRESLETENVLDDIK 604
            L  +S  E       ++Q  N    + K   Q++      K     ++  + E +  ++K
Sbjct: 931  LELNSMQEQ------LIQAQNTLKQNEKEEQQLQGNINELKQSSEQKKK-QIEALQGELK 983

Query: 605  SA---GSHEPIKIQTRSDHGGCELASVLQLNPCRTGKIKSLQNNQDVS---FENIQWSI- 657
             A    +    K+Q +      ELA+  +       KI  LQNN + S   F+ +Q    
Sbjct: 984  IAVLQKTELENKLQQQLTQAAQELAAEKE-------KISVLQNNYEKSQETFKQLQSDFY 1036

Query: 658  DPGADLSQYKMDVTVIDTK--------------DGSQSKLGGETVDMDCTLVSETVLLKM 703
               ++L   + D+  ++ K               G+Q+KL  E      TL  ++   + 
Sbjct: 1037 GRESELLATRQDLKSVEEKLSLAQEDLISNRNQIGNQNKLIQELKTAKATLEQDSAKKEQ 1096

Query: 704  KKQEQ-------KGEKSSNEERKMNDSLEDMFDRTTHEEYESCLADSFSQAADEEEELST 756
            + QE+       + EKS  E+  +N+              +S LA+       +E+E++ 
Sbjct: 1097 QLQERCKALQDIQKEKSLKEKELVNE--------------KSKLAEIEEIKCRQEKEITK 1142

Query: 757  ATKKLHTHGDKQDKVKQ 773
              ++L +H  K + +K+
Sbjct: 1143 LNEELKSH--KLESIKE 1157



 Score = 30.8 bits (68), Expect = 5.9
 Identities = 31/122 (25%), Positives = 56/122 (45%), Gaps = 7/122 (5%)

Query: 33  REVQGLQVKVTKLKQERILDAQRL---EEFFTKNQQLREQQKVLHETIKVL---EDRLRA 86
           +E+Q L+  V +L Q+     + L   E+ +TK ++   ++ V  + I+     +D    
Sbjct: 288 QELQKLKSSVNELTQKNQTLTENLLKKEQDYTKLEEKHNEESVSKKNIQATLHQKDLDCQ 347

Query: 87  GLCDRCAVTEEHMRKKQQEFENIRQQNLKLITELMNERNTLQEENKKLSEQLQQKIENDQ 146
            L  R + +E  + +   E     +   KL  EL +E  T  +  K   +QLQQ+ E  +
Sbjct: 348 QLQSRLSASETSLHRIHVELSEKGEATQKLKEEL-SEVETKYQHLKAEFKQLQQQREEKE 406

Query: 147 QH 148
           QH
Sbjct: 407 QH 408


>gi|149999352 forkhead box P2 isoform II [Homo sapiens]
          Length = 740

 Score = 44.7 bits (104), Expect = 4e-04
 Identities = 35/177 (19%), Positives = 77/177 (43%), Gaps = 22/177 (12%)

Query: 6   SSCGSPNSADTSSDFKDLWTKLKEC---------HDREVQGLQVKVT------------- 43
           S   SP S+D     ++L  + K C         H      + V V              
Sbjct: 71  SGLKSPKSSDKQRPLQELLPETKLCICGHSSGDGHPHNTFAVPVSVAMMTPQVITPQQMQ 130

Query: 44  KLKQERILDAQRLEEFFTKNQQLREQQKVLHETIKVLEDRLRAGLCDRCAVTEEHMRKKQ 103
           ++ Q+++L  Q+L+    + Q +  QQ+ L E  K  +++L   L  +    ++  +++Q
Sbjct: 131 QILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQQQQ 190

Query: 104 QEFENIRQQNLKLITELMNERNTLQEENKKLSEQLQQKIENDQQHQAAELECEEDVI 160
           Q+ +  +QQ  +   +   ++   Q+   K +++ QQ+ +  QQ  A +L  ++ ++
Sbjct: 191 QQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLL 247


>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
            sapiens]
          Length = 1972

 Score = 44.7 bits (104), Expect = 4e-04
 Identities = 78/380 (20%), Positives = 154/380 (40%), Gaps = 51/380 (13%)

Query: 23   LWTKLKEC-----HDREVQGLQVKVTKLKQERILDAQRLEEFFTKNQQLREQQKVLHETI 77
            L+TK+K        + E+Q  + ++ K K+ +      L+E   K+ QL E++ +L E +
Sbjct: 837  LFTKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQL 896

Query: 78   KVLEDRLRAGLCDRCAVTEEHMRKKQQEFENIRQQNLKLITELMNERNTLQEENKKLSEQ 137
            +  E  L A            +  K+QE E I  +    + E  +    LQ E KK+++Q
Sbjct: 897  QA-ETELYA----EAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQ 951

Query: 138  LQQKIENDQQHQAAELECE-EDVIPDSPITAF--SFSGVNRLRRKENPHVRYIEQTHTKL 194
            +    E  ++ +AA  + + E V  ++ I         ++    K +   + +E+  + L
Sbjct: 952  MLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDL 1011

Query: 195  EHSVCANEMRKVSKSSTHPQHNPNENEILV-ADTYDQSQSPMAKAHGTSSYTPDKSSFN- 252
              ++   E +  + +    +H    +E+ V     ++S+  + K         D S F+ 
Sbjct: 1012 TTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKL--KRKLEGDASDFHE 1069

Query: 253  -LATVVAETLGLGVQ---EESETQGPMSPLGDEL---------YHCLEGN----HKKQPF 295
             +A + A+   L +Q   +E E Q  ++ L DE+            LEG+     +    
Sbjct: 1070 QIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDS 1129

Query: 296  EESTRNTEDSLR-------------FSDSTSKTPPQEELPTRVSSPVFGATSSIKSGLDL 342
            E + RN  +  +               D+   T  Q+EL  +    V    + +K  LD 
Sbjct: 1130 ERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEV----TVLKKALDE 1185

Query: 343  NTSLSPSLLQPGKKKHLKTL 362
             T    + +Q  ++KH + +
Sbjct: 1186 ETRSHEAQVQEMRQKHAQAV 1205



 Score = 33.9 bits (76), Expect = 0.70
 Identities = 31/138 (22%), Positives = 67/138 (48%), Gaps = 10/138 (7%)

Query: 21   KDLWTKLKECHDREVQGLQVKVTKLKQERILDAQRLEEFFTKNQQLREQQKVLHETIKVL 80
            K L   LK+   +    ++ +   +KQ R L AQ +++F  + +  R  +  +  T K  
Sbjct: 1620 KKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQ-MKDFQRELEDARASRDEIFATAKEN 1678

Query: 81   EDRLRAGLCDRCAVTEE----HMRKKQQEFENIRQQNLKLITELMNERNTLQEENKKLS- 135
            E + ++   D   + E+       +KQ + E  +++  + +   ++ RN LQ+E ++L  
Sbjct: 1679 EKKAKSLEADLMQLQEDLAAAERARKQADLE--KEELAEELASSLSGRNALQDEKRRLEA 1736

Query: 136  --EQLQQKIENDQQHQAA 151
               QL++++E +Q +  A
Sbjct: 1737 RIAQLEEELEEEQGNMEA 1754


>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
            sapiens]
          Length = 1979

 Score = 44.7 bits (104), Expect = 4e-04
 Identities = 78/380 (20%), Positives = 154/380 (40%), Gaps = 51/380 (13%)

Query: 23   LWTKLKEC-----HDREVQGLQVKVTKLKQERILDAQRLEEFFTKNQQLREQQKVLHETI 77
            L+TK+K        + E+Q  + ++ K K+ +      L+E   K+ QL E++ +L E +
Sbjct: 844  LFTKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQL 903

Query: 78   KVLEDRLRAGLCDRCAVTEEHMRKKQQEFENIRQQNLKLITELMNERNTLQEENKKLSEQ 137
            +  E  L A            +  K+QE E I  +    + E  +    LQ E KK+++Q
Sbjct: 904  QA-ETELYA----EAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQ 958

Query: 138  LQQKIENDQQHQAAELECE-EDVIPDSPITAF--SFSGVNRLRRKENPHVRYIEQTHTKL 194
            +    E  ++ +AA  + + E V  ++ I         ++    K +   + +E+  + L
Sbjct: 959  MLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDL 1018

Query: 195  EHSVCANEMRKVSKSSTHPQHNPNENEILV-ADTYDQSQSPMAKAHGTSSYTPDKSSFN- 252
              ++   E +  + +    +H    +E+ V     ++S+  + K         D S F+ 
Sbjct: 1019 TTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKL--KRKLEGDASDFHE 1076

Query: 253  -LATVVAETLGLGVQ---EESETQGPMSPLGDEL---------YHCLEGN----HKKQPF 295
             +A + A+   L +Q   +E E Q  ++ L DE+            LEG+     +    
Sbjct: 1077 QIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDS 1136

Query: 296  EESTRNTEDSLR-------------FSDSTSKTPPQEELPTRVSSPVFGATSSIKSGLDL 342
            E + RN  +  +               D+   T  Q+EL  +    V    + +K  LD 
Sbjct: 1137 ERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEV----TVLKKALDE 1192

Query: 343  NTSLSPSLLQPGKKKHLKTL 362
             T    + +Q  ++KH + +
Sbjct: 1193 ETRSHEAQVQEMRQKHAQAV 1212



 Score = 33.9 bits (76), Expect = 0.70
 Identities = 31/138 (22%), Positives = 67/138 (48%), Gaps = 10/138 (7%)

Query: 21   KDLWTKLKECHDREVQGLQVKVTKLKQERILDAQRLEEFFTKNQQLREQQKVLHETIKVL 80
            K L   LK+   +    ++ +   +KQ R L AQ +++F  + +  R  +  +  T K  
Sbjct: 1627 KKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQ-MKDFQRELEDARASRDEIFATAKEN 1685

Query: 81   EDRLRAGLCDRCAVTEE----HMRKKQQEFENIRQQNLKLITELMNERNTLQEENKKLS- 135
            E + ++   D   + E+       +KQ + E  +++  + +   ++ RN LQ+E ++L  
Sbjct: 1686 EKKAKSLEADLMQLQEDLAAAERARKQADLE--KEELAEELASSLSGRNALQDEKRRLEA 1743

Query: 136  --EQLQQKIENDQQHQAA 151
               QL++++E +Q +  A
Sbjct: 1744 RIAQLEEELEEEQGNMEA 1761


>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
            sapiens]
          Length = 1945

 Score = 44.7 bits (104), Expect = 4e-04
 Identities = 78/380 (20%), Positives = 154/380 (40%), Gaps = 51/380 (13%)

Query: 23   LWTKLKEC-----HDREVQGLQVKVTKLKQERILDAQRLEEFFTKNQQLREQQKVLHETI 77
            L+TK+K        + E+Q  + ++ K K+ +      L+E   K+ QL E++ +L E +
Sbjct: 844  LFTKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQL 903

Query: 78   KVLEDRLRAGLCDRCAVTEEHMRKKQQEFENIRQQNLKLITELMNERNTLQEENKKLSEQ 137
            +  E  L A            +  K+QE E I  +    + E  +    LQ E KK+++Q
Sbjct: 904  QA-ETELYA----EAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQ 958

Query: 138  LQQKIENDQQHQAAELECE-EDVIPDSPITAF--SFSGVNRLRRKENPHVRYIEQTHTKL 194
            +    E  ++ +AA  + + E V  ++ I         ++    K +   + +E+  + L
Sbjct: 959  MLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDL 1018

Query: 195  EHSVCANEMRKVSKSSTHPQHNPNENEILV-ADTYDQSQSPMAKAHGTSSYTPDKSSFN- 252
              ++   E +  + +    +H    +E+ V     ++S+  + K         D S F+ 
Sbjct: 1019 TTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKL--KRKLEGDASDFHE 1076

Query: 253  -LATVVAETLGLGVQ---EESETQGPMSPLGDEL---------YHCLEGN----HKKQPF 295
             +A + A+   L +Q   +E E Q  ++ L DE+            LEG+     +    
Sbjct: 1077 QIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDS 1136

Query: 296  EESTRNTEDSLR-------------FSDSTSKTPPQEELPTRVSSPVFGATSSIKSGLDL 342
            E + RN  +  +               D+   T  Q+EL  +    V    + +K  LD 
Sbjct: 1137 ERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEV----TVLKKALDE 1192

Query: 343  NTSLSPSLLQPGKKKHLKTL 362
             T    + +Q  ++KH + +
Sbjct: 1193 ETRSHEAQVQEMRQKHAQAV 1212



 Score = 33.9 bits (76), Expect = 0.70
 Identities = 31/138 (22%), Positives = 67/138 (48%), Gaps = 10/138 (7%)

Query: 21   KDLWTKLKECHDREVQGLQVKVTKLKQERILDAQRLEEFFTKNQQLREQQKVLHETIKVL 80
            K L   LK+   +    ++ +   +KQ R L AQ +++F  + +  R  +  +  T K  
Sbjct: 1627 KKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQ-MKDFQRELEDARASRDEIFATAKEN 1685

Query: 81   EDRLRAGLCDRCAVTEE----HMRKKQQEFENIRQQNLKLITELMNERNTLQEENKKLS- 135
            E + ++   D   + E+       +KQ + E  +++  + +   ++ RN LQ+E ++L  
Sbjct: 1686 EKKAKSLEADLMQLQEDLAAAERARKQADLE--KEELAEELASSLSGRNALQDEKRRLEA 1743

Query: 136  --EQLQQKIENDQQHQAA 151
               QL++++E +Q +  A
Sbjct: 1744 RIAQLEEELEEEQGNMEA 1761


>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
            sapiens]
          Length = 1938

 Score = 44.7 bits (104), Expect = 4e-04
 Identities = 78/380 (20%), Positives = 154/380 (40%), Gaps = 51/380 (13%)

Query: 23   LWTKLKEC-----HDREVQGLQVKVTKLKQERILDAQRLEEFFTKNQQLREQQKVLHETI 77
            L+TK+K        + E+Q  + ++ K K+ +      L+E   K+ QL E++ +L E +
Sbjct: 837  LFTKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKELEQKHSQLTEEKNLLQEQL 896

Query: 78   KVLEDRLRAGLCDRCAVTEEHMRKKQQEFENIRQQNLKLITELMNERNTLQEENKKLSEQ 137
            +  E  L A            +  K+QE E I  +    + E  +    LQ E KK+++Q
Sbjct: 897  QA-ETELYA----EAEEMRVRLAAKKQELEEILHEMEARLEEEEDRGQQLQAERKKMAQQ 951

Query: 138  LQQKIENDQQHQAAELECE-EDVIPDSPITAF--SFSGVNRLRRKENPHVRYIEQTHTKL 194
            +    E  ++ +AA  + + E V  ++ I         ++    K +   + +E+  + L
Sbjct: 952  MLDLEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDL 1011

Query: 195  EHSVCANEMRKVSKSSTHPQHNPNENEILV-ADTYDQSQSPMAKAHGTSSYTPDKSSFN- 252
              ++   E +  + +    +H    +E+ V     ++S+  + K         D S F+ 
Sbjct: 1012 TTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKL--KRKLEGDASDFHE 1069

Query: 253  -LATVVAETLGLGVQ---EESETQGPMSPLGDEL---------YHCLEGN----HKKQPF 295
             +A + A+   L +Q   +E E Q  ++ L DE+            LEG+     +    
Sbjct: 1070 QIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDS 1129

Query: 296  EESTRNTEDSLR-------------FSDSTSKTPPQEELPTRVSSPVFGATSSIKSGLDL 342
            E + RN  +  +               D+   T  Q+EL  +    V    + +K  LD 
Sbjct: 1130 ERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEV----TVLKKALDE 1185

Query: 343  NTSLSPSLLQPGKKKHLKTL 362
             T    + +Q  ++KH + +
Sbjct: 1186 ETRSHEAQVQEMRQKHAQAV 1205



 Score = 33.9 bits (76), Expect = 0.70
 Identities = 31/138 (22%), Positives = 67/138 (48%), Gaps = 10/138 (7%)

Query: 21   KDLWTKLKECHDREVQGLQVKVTKLKQERILDAQRLEEFFTKNQQLREQQKVLHETIKVL 80
            K L   LK+   +    ++ +   +KQ R L AQ +++F  + +  R  +  +  T K  
Sbjct: 1620 KKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQ-MKDFQRELEDARASRDEIFATAKEN 1678

Query: 81   EDRLRAGLCDRCAVTEE----HMRKKQQEFENIRQQNLKLITELMNERNTLQEENKKLS- 135
            E + ++   D   + E+       +KQ + E  +++  + +   ++ RN LQ+E ++L  
Sbjct: 1679 EKKAKSLEADLMQLQEDLAAAERARKQADLE--KEELAEELASSLSGRNALQDEKRRLEA 1736

Query: 136  --EQLQQKIENDQQHQAA 151
               QL++++E +Q +  A
Sbjct: 1737 RIAQLEEELEEEQGNMEA 1754


>gi|31563507 GRIP and coiled-coil domain-containing 2 [Homo sapiens]
          Length = 1684

 Score = 44.3 bits (103), Expect = 5e-04
 Identities = 45/186 (24%), Positives = 88/186 (47%), Gaps = 15/186 (8%)

Query: 35   VQGLQVKVTKLKQERILDAQRLEEFFTKNQQLREQQ-KVLHETIKVLEDRLRAGLCDRCA 93
            +  L++K+   +    ++   L+   +++  L E+  K+L ET+   E  LR  LC   +
Sbjct: 1358 IDQLKIKLQDSQNNLQINVSELQTLQSEHDTLLERHNKMLQETVSK-EAELREKLC---S 1413

Query: 94   VTEEHMRKKQQEFENIRQ---QNLKLITELMNERNTLQEENKKLSEQLQQKIENDQQHQA 150
            +  E+M  K +  + + Q   QN  L     ++   LQEE++K  E LQQ++    + +A
Sbjct: 1414 IQSENMMMKSEHTQTVSQLTSQNEVLRNSFRDQVRHLQEEHRKTVETLQQQL---SKMEA 1470

Query: 151  AELECEEDVIPDSPITAFSFSGVNRLRRKENPHVRYIE-QTHTKLE-HSVCANEMRKVSK 208
               + + +    SP++  S   +  LR + N  +  ++  T T+ E   +   +   VS 
Sbjct: 1471 QLFQLKNEPTTRSPVS--SQQSLKNLRERRNTDLPLLDMHTVTREEGEGMETTDTESVSS 1528

Query: 209  SSTHPQ 214
            +ST+ Q
Sbjct: 1529 ASTYTQ 1534



 Score = 38.9 bits (89), Expect = 0.022
 Identities = 41/182 (22%), Positives = 83/182 (45%), Gaps = 33/182 (18%)

Query: 29  ECHDREVQGL----QVKVTKLKQERILDAQR-----------LEEFFTKNQQLREQQKVL 73
           E H+REVQ L    Q ++++L +  + D+++           L+E     QQ +++  + 
Sbjct: 420 EQHNREVQSLKEQHQKEISELNETFLSDSEKEKLTLMFEIQGLKEQCENLQQEKQEAILN 479

Query: 74  HETIKVLEDRLRAGLCDRCAVTEEHMRKKQQEFENIRQQNLKLITELMNERNTLQEENKK 133
           +E+++ + + L+  L        E   K  QEFE+++QQ    + EL  +  T   E   
Sbjct: 480 YESLREIMEILQTEL-------GESAGKISQEFESMKQQQASDVHELQQKLRTAFTEKDA 532

Query: 134 LSEQLQQKIENDQQHQAAELECEEDVIPDSPITAFSFSGVNRLRRKENPHVRYIEQTHTK 193
           L E +     N  Q +  +L  +++++P+   T      +  L+ K   ++  + Q  T 
Sbjct: 533 LLETV-----NRLQGENEKLLSQQELVPELENT------IKNLQEKNGVYLLSLSQRDTM 581

Query: 194 LE 195
           L+
Sbjct: 582 LK 583



 Score = 35.0 bits (79), Expect = 0.31
 Identities = 32/141 (22%), Positives = 63/141 (44%), Gaps = 26/141 (18%)

Query: 15  DTSSDFKDLWTKLKECHD---REVQGLQVKV----TKLKQERILDAQRLEEFFTKNQQLR 67
           D+ +   D   +L++ H    +E++ L+ ++    +K  +++    ++LEE      +L 
Sbjct: 108 DSVTKMGDAHKELEQSHINYVKEIENLKNELMAVRSKYSEDKANLQKQLEEAMNTQLELS 167

Query: 68  EQQKVLHETIKVLEDRLRAGLCDRCAVTEEHMRKKQQEFENIRQQNLKLITELMNERNTL 127
           EQ K  + +                   E++++K Q+E E IR    + I  L  + +  
Sbjct: 168 EQLKFQNNS-------------------EDNVKKLQEEIEKIRPGFEEQILYLQKQLDAT 208

Query: 128 QEENKKLSEQLQQKIENDQQH 148
            +E K+   QLQ  IE + QH
Sbjct: 209 TDEKKETVTQLQNIIEANSQH 229



 Score = 32.3 bits (72), Expect = 2.0
 Identities = 35/147 (23%), Positives = 71/147 (48%), Gaps = 30/147 (20%)

Query: 15   DTSSDFKDLWTKL----KECHDREVQGLQVKVTKLKQERILDAQRLEEFFTKNQQLREQQ 70
            D  S  K+L  K+    KEC ++E +  ++K+  +K ++ LD+ R E      Q ++E+ 
Sbjct: 941  DPLSSVKELEEKIENLEKECKEKEEKINKIKLVAVKAKKELDSSRKE-----TQTVKEEL 995

Query: 71   KVLHETIKVLEDRLRAGLCDRCAVTEEHMRKKQQEFENIRQQNLKLITELMNERNTLQEE 130
                E+++  +D+L A + D     E +             +NL L  E  +E+  +++E
Sbjct: 996  ----ESLRSEKDQLSASMRDLIQGAESY-------------KNLLLEYEKQSEQLDVEKE 1038

Query: 131  NKKLSEQLQQKIEN-DQQHQAAELECE 156
                +   + +IE+  +Q + + L+CE
Sbjct: 1039 R---ANNFEHRIEDLTRQLRNSTLQCE 1062



 Score = 31.6 bits (70), Expect = 3.5
 Identities = 34/157 (21%), Positives = 67/157 (42%), Gaps = 16/157 (10%)

Query: 49  RILDAQRLEEFFTKNQQLREQQKVLHETIKVLEDRLRAGLCDRCAVTEEHMRKKQQEFEN 108
           ++L+ +++++ F K Q     +++  E   V ED     + +      E + K  +E  N
Sbjct: 743 KLLENEQVQKLFVKTQLYGFLKEMGSE---VSEDSEEKDVVNVLQAVGESLAKINEEKCN 799

Query: 109 IRQQNLKLITELMNERNTLQEENKKLSEQLQQKIENDQQH------QAAELECEEDVIPD 162
           +  Q  + + EL  E   LQEE+    E+L+  + + +Q       +  E++ E++ +  
Sbjct: 800 LAFQRDEKVLELEKEIKCLQEESVVQCEELKSLLRDYEQEKVLLRKELEEIQSEKEALQS 859

Query: 163 SPITAFSFSGVNRLRRKENPH----VRYIEQTHTKLE 195
                      N   R EN +    V  + QT +K E
Sbjct: 860 D---LLEMKNANEKTRLENQNLLIQVEEVSQTCSKSE 893



 Score = 30.4 bits (67), Expect = 7.7
 Identities = 44/164 (26%), Positives = 73/164 (44%), Gaps = 31/164 (18%)

Query: 9   GSPNSADTSSDFKDLWTKLKECHDREVQGLQVKVTKLKQERILDAQRLEEFFTKNQQLRE 68
           G  NS     D  D   KLK  H+ E+     K  + ++  +   +++E+    N +L  
Sbjct: 587 GKINSLTEEKD--DFINKLKNSHE-EMDNFHKKCEREERLILELGKKVEQTIQYNSEL-- 641

Query: 69  QQKVLHETIKVLEDRLRAGLCDRCAVTEEHMRKKQQEFENIRQQ--NLKLITE----LMN 122
           +QKV         + L  GL       EE +++K Q  + + +    +K+++E    L  
Sbjct: 642 EQKV---------NELTGGL-------EETLKEKDQNDQKLEKLMVQMKVLSEDKEVLSA 685

Query: 123 ERNTLQEENKKLSEQLQQKIENDQQHQAAELECEEDVIPDSPIT 166
           E  +L EEN KLS + +Q +  D +     L  +EDVI    IT
Sbjct: 686 EVKSLYEENNKLSSEKKQ-LSRDLE---VFLSQKEDVILKEHIT 725


>gi|59806361 hypothetical protein LOC387104 [Homo sapiens]
          Length = 947

 Score = 44.3 bits (103), Expect = 5e-04
 Identities = 67/296 (22%), Positives = 124/296 (41%), Gaps = 33/296 (11%)

Query: 6   SSCGSPNSADTSSDFKDLWTKLKECHDREVQGLQVKVTKLKQERILDAQR---LEEFFTK 62
           SS   P       + ++   KL+E    E + L+ ++ +L+ E  +D  R    EE   +
Sbjct: 338 SSQPHPQQLQEQEEMQEEMEKLRE----ENETLKNEIDELRTE--MDEMRDTFFEEDACQ 391

Query: 63  NQQLREQQKVLHETIKVLEDRLRAGLCDRCAVTE------EHMRKKQQEFENIRQQNLKL 116
            Q++R + +  ++  ++L+ RLR     R    +      E +R  +Q+ +  +  +++L
Sbjct: 392 LQEMRHELERANKNCRILQYRLRKAERKRLRYAQTGEIDGELLRSLEQDLKVAKDVSVRL 451

Query: 117 ITELMN---ERNTLQEENKKLSEQL------QQKIENDQQHQAAELECEEDVIPDSPITA 167
             EL N   +R T ++EN+KL +QL      +Q ++N+ + +  EL  +     D P   
Sbjct: 452 HHELENVEEKRTTTEDENEKLRQQLIEVEIAKQALQNELE-KMKELSLKRRGSKDLP--- 507

Query: 168 FSFSGVNRLRRKENPHVRYIEQTHTKLEHSVCANEMRKVSKSSTHPQHNPNENEILVADT 227
            S     +   +E+      +    K E ++   +M K+ K     +H   +      D 
Sbjct: 508 KSEKKAQQTPTEEDNEDLKCQLQFVKEEAALMRKKMAKIDKEKDRFEHELQKYRSFYGDL 567

Query: 228 YDQSQSPMAKAHGTSSYTPDKSSFNLATVVAETLGLG---VQEESETQGPMSPLGD 280
              S  P  +A G  S    +    L  V  E   LG   V+ E E +G  + L D
Sbjct: 568 --DSPLPKGEAGGPPSTREAELKLRLRLVEEEANILGRKIVELEVENRGLKAELDD 621


>gi|148596984 golgi autoantigen, golgin subfamily b, macrogolgin (with
            transmembrane signal), 1 [Homo sapiens]
          Length = 3259

 Score = 44.3 bits (103), Expect = 5e-04
 Identities = 99/488 (20%), Positives = 188/488 (38%), Gaps = 78/488 (15%)

Query: 31   HDREVQGLQVKVTKLKQ---------------ERILDAQRL--EEFFTKNQQLREQQKVL 73
            HD  ++ LQV++ ++KQ               +R L A  +  +E   +N+ L+E+  + 
Sbjct: 1450 HDERIKQLQVELCEMKQKPEEIGEESRAKQQIQRKLQAALISRKEALKENKSLQEELSLA 1509

Query: 74   HETIKVL-------------EDRLRAGLCDRCAVTEEHMRKKQQEFENIRQQN------- 113
              TI+ L             +++ +  +  R A+ +E   K   E +    +N       
Sbjct: 1510 RGTIERLTKSLADVESQVSAQNKEKDTVLGRLALLQEERDKLITEMDRSLLENQSLSSSC 1569

Query: 114  --LKLITE-LMNERNTLQEENKKL-SEQLQQKIENDQQHQAAELECE------EDVIPDS 163
              LKL  E L  ++  L +E + L S ++ +  E  ++H+  + E E      E+V  ++
Sbjct: 1570 ESLKLALEGLTEDKEKLVKEIESLKSSKIAESTEWQEKHKELQKEYEILLQSYENVSNEA 1629

Query: 164  PITAFSFSGVNRLRRKENPHVRYIEQTHTKLEHSV---------CANEMRKVSKSSTHP- 213
                     V + +++    +R  E    + E  +            +MRK +KS     
Sbjct: 1630 ERIQHVVEAVRQEKQELYGKLRSTEANKKETEKQLQEAEQEMEEMKEKMRKFAKSKQQKI 1689

Query: 214  QHNPNENEILVADTY---DQSQSPMAKAHGTSSYTPDKSSFNLATVVAETLGLGVQEESE 270
                 EN+ L A+ +   D ++  M      SS    K       +  ETL    Q    
Sbjct: 1690 LELEEENDRLRAEVHPAGDTAKECMETL--LSSNASMKEELERVKMEYETLSKKFQSLMS 1747

Query: 271  TQGPMSPLGDELYHCLEGNHKKQPFEESTRNTEDSLRFSDSTSKTPP--QEELPTRVSSP 328
             +  +S    +L H +EGN  KQ   E+T   ++    ++  +++ P   EE  +   S 
Sbjct: 1748 EKDSLSEEVQDLKHQIEGNVSKQANLEATEKHDNQTNVTEEGTQSIPGETEEQDSLSMST 1807

Query: 329  VFGATSSIKSGLDLNTSLSPSLLQPGK-KKHLKTLPFSNTCISRLEKTRSK--------- 378
                + S+ S    N ++S       +   +L+ +      I+ LE+ + K         
Sbjct: 1808 RPTCSESVPSAKSANPAVSKDFSSHDEINNYLQQIDQLKERIAGLEEEKQKNKEFSQTLE 1867

Query: 379  SEDSALFTHHSLGSEVNKIIIQSSNKQILINKNISESLGE----QNRTEYGKDSNTDKHL 434
            +E + L +  S      K++ +   K  L+N+ I E L      +   E  KD   ++ +
Sbjct: 1868 NEKNTLLSQISTKDGELKMLQEEVTKMNLLNQQIQEELSRVTKLKETAEEEKDDLEERLM 1927

Query: 435  EPLKSLGG 442
              L  L G
Sbjct: 1928 NQLAELNG 1935



 Score = 37.4 bits (85), Expect = 0.063
 Identities = 51/221 (23%), Positives = 103/221 (46%), Gaps = 34/221 (15%)

Query: 32   DREVQGLQVK----VTKLK------------QERILD-AQRLEEFFTKNQQLREQQ-KVL 73
            D+EVQ LQ      VT+L             ++R++D A++ E  F+   Q +E++ ++ 
Sbjct: 2170 DKEVQQLQENLDSTVTQLAAFTKSMSSLQDDRDRVIDEAKKWERKFSDAIQSKEEEIRLK 2229

Query: 74   HETIKVLEDRLRAGLC--DRCAVTEEHMRKKQQEFENIRQQNLKLITELMNERNTLQEEN 131
             +   VL+D+LR      +   +    +   +Q +E+  Q  ++L  ++ +   TLQ EN
Sbjct: 2230 EDNCSVLKDQLRQMSIHMEELKINISRLEHDKQIWESKAQTEVQLQQKVCD---TLQGEN 2286

Query: 132  KKLSEQLQQ--KIENDQQHQAAELECEEDVIPDSPITAFSFSGVNRLRRKENPHVRYIEQ 189
            K+L  QL++   + +  Q++ A+LE E   + D  +T  S + + + + ++      I Q
Sbjct: 2287 KELLSQLEETRHLYHSSQNELAKLESELKSLKDQ-LTDLS-NSLEKCKEQKGNLEGIIRQ 2344

Query: 190  THTKLEHSVCANEMRKVS-------KSSTHPQHNPNENEIL 223
                +++S  + E  +          S  H + N  E +I+
Sbjct: 2345 QEADIQNSKFSYEQLETDLQASRELTSRLHEEINMKEQKII 2385



 Score = 37.0 bits (84), Expect = 0.082
 Identities = 40/152 (26%), Positives = 65/152 (42%), Gaps = 22/152 (14%)

Query: 16  TSSDFKDLWTKLKECHDRE-VQGLQVKVTKLKQER---ILDAQRLEEFFTKNQQLREQQK 71
           + + F D++ +  +    E +  LQ +V +L+ E+   +L +  LEE   +N++L  Q  
Sbjct: 450 SQTSFPDVYNEGTQAVTEENIASLQKRVVELENEKGALLLSSIELEELKAENEKLSSQ-- 507

Query: 72  VLHETIKVLEDRLRAGLCDR-----CAVTEEHMRKKQQE------FENIRQQNLKLITEL 120
                I +LE + R G  DR       V   + R    E       EN   Q  K ++ L
Sbjct: 508 -----ITLLEAQNRTGEADREVSEISIVDIANKRSSSAEESGQDVLENTFSQKHKELSVL 562

Query: 121 MNERNTLQEENKKLSEQLQQKIENDQQHQAAE 152
           + E    QEE   L  QLQ K   +  H+  +
Sbjct: 563 LLEMKEAQEEIAFLKLQLQGKRAEEADHEVLD 594



 Score = 36.6 bits (83), Expect = 0.11
 Identities = 39/188 (20%), Positives = 85/188 (45%), Gaps = 19/188 (10%)

Query: 26   KLKECHDREVQGLQVKVTKLKQERILDAQRLEEFFTKNQQLREQQKVLHETIKVLEDRLR 85
            +L++ HD+E++ L+  +++ ++E I+  +  ++   K  QL E  K    TIK    + +
Sbjct: 2401 ELRQQHDKEIKELENLLSQEEEENIVLEEENKKAVDKTNQLMETLK----TIKKENIQQK 2456

Query: 86   AGLC-----------DRCAVTEEHMRKKQQEFENIRQQNLKLITELMNERNTLQEENKKL 134
            A L            DR  +  ++ + +++    I +++ +LI E   E N L+EE + L
Sbjct: 2457 AQLDSFVKSMSSLQNDRDRIVGDYQQLEERHLSIILEKD-QLIQEAAAENNKLKEEIRGL 2515

Query: 135  SEQLQQKIENDQQHQAAELECEEDVIPDSPITAFSFSGVNRLRRKENPHVRYIEQTHTKL 194
               +      + +  A  ++  ED+   + +     S   +L   +    + +E  + KL
Sbjct: 2516 RSHMDDLNSENAKLDAELIQYREDL---NQVITIKDSQQKQLLEVQLQQNKELENKYAKL 2572

Query: 195  EHSVCANE 202
            E  +  +E
Sbjct: 2573 EEKLKESE 2580



 Score = 35.0 bits (79), Expect = 0.31
 Identities = 38/130 (29%), Positives = 62/130 (47%), Gaps = 17/130 (13%)

Query: 22   DLWTKLKECHDREVQGLQVKVTKLKQERILDAQ-RLEEFFTKNQQLREQQKVLHETIKVL 80
            DL   L++C  +E +G    + + ++  I +++   E+  T  Q  RE    LHE I + 
Sbjct: 2323 DLSNSLEKC--KEQKGNLEGIIRQQEADIQNSKFSYEQLETDLQASRELTSRLHEEINMK 2380

Query: 81   EDRLRAGLCDRCAVTEEHMRKKQQEFENIRQQNLKLITELMN-------ERNTLQEENKK 133
            E ++ + L  +    EE +   Q     +RQQ+ K I EL N       E   L+EENKK
Sbjct: 2381 EQKIISLLSGK----EEAI---QVAIAELRQQHDKEIKELENLLSQEEEENIVLEEENKK 2433

Query: 134  LSEQLQQKIE 143
              ++  Q +E
Sbjct: 2434 AVDKTNQLME 2443



 Score = 33.9 bits (76), Expect = 0.70
 Identities = 41/183 (22%), Positives = 78/183 (42%), Gaps = 35/183 (19%)

Query: 12  NSADTSSDFKDLWTKLKECHDREVQGLQVKVTKLKQERILDAQ-RLEEFFTKNQQLREQ- 69
           +S +   + + +  KL+E  +  +  LQ ++T+ + E+   +   +EEF    QQL+E+ 
Sbjct: 138 SSTEEEMEIEKIKHKLQE-KEELISTLQAQLTQAQAEQPAQSSTEMEEFVMMKQQLQEKE 196

Query: 70  -------------------QKVLHET-------IKVLEDRLRAGLCDRCAVTEEH----- 98
                              Q+V+ E        +++ ED L   +      TE       
Sbjct: 197 EFISTLQAQLSQTQAEQAAQQVVREKDARFETQVRLHEDELLQLVTQADVETEMQQKLRV 256

Query: 99  MRKKQQEFENIRQQNLKLITELMNERNTLQEENKKLSEQLQQ-KIENDQQHQAAELECEE 157
           +++K +E E       +++  L  E    ++ N+ LS+QLQQ + E++      E E EE
Sbjct: 257 LQRKLEEHEESLVGRAQVVDLLQQELTAAEQRNQILSQQLQQMEAEHNTLRNTVETEREE 316

Query: 158 DVI 160
             I
Sbjct: 317 SKI 319


>gi|223634475 golgi autoantigen, golgin subfamily a, 6D [Homo
           sapiens]
          Length = 693

 Score = 43.9 bits (102), Expect = 7e-04
 Identities = 51/221 (23%), Positives = 90/221 (40%), Gaps = 27/221 (12%)

Query: 36  QGLQVKVTKLKQERILDAQRLEEFFTKNQQLREQQKVLH---ETIKVLEDRLRAGLCDRC 92
           Q LQ +   L+++     +  E    +N++LREQQK L    E ++  E RLR       
Sbjct: 337 QRLQEQEEMLREQEAQRVREQERLCEQNERLREQQKTLQEQGERLRKQEQRLRK------ 390

Query: 93  AVTEEHMRKKQQEFENIRQQNLKLITELMNERNTLQEENKKLSEQLQQKIENDQQHQAAE 152
              EE +RK+++  +   ++       L  +   LQ++ ++L+     K++     Q AE
Sbjct: 391 --QEERLRKEEERLQKQEKRLWDQEERLWKKEERLQKQEERLALSQNHKLDK----QLAE 444

Query: 153 LECEEDVIPDSPITAFSF-SGVNRLRRK-ENPHVRYIEQTHTKLEHSVCANEMRKVSKSS 210
            +C  + + +   +A      V  L+ K +  H+    Q + +LE  +    +       
Sbjct: 445 PQCSFEDLNNEKKSALQLEQQVKELQEKLDEEHLEAASQRNQQLETQLSLVALPGEGDGG 504

Query: 211 TH--------PQHNPNENEILVADTYDQS--QSPMAKAHGT 241
            H        P+  PN  E L +     S    P  KA GT
Sbjct: 505 QHLDSEEEEAPRPTPNIPEDLESREATSSFMDLPKEKADGT 545



 Score = 38.9 bits (89), Expect = 0.022
 Identities = 61/286 (21%), Positives = 118/286 (41%), Gaps = 51/286 (17%)

Query: 38  LQVKVTKLKQERILDAQRLEEFFT-----KNQ-----------------QLREQQKVLHE 75
           + V+   LK+E+  D  R++E        KNQ                 QL+++ K L +
Sbjct: 250 MSVEARTLKEEKKRDIHRIQELERSLSELKNQMAEPPSLAPPAVTSVVEQLQDEAKHLRQ 309

Query: 76  TIKVLEDRLRAGLCDRCA---VTEEHMRKKQQEFENIRQQNLKLITE---LMNERNTLQE 129
            ++ LE +L++ + +  A   +++E  ++ Q++ E +R+Q  + + E   L  +   L+E
Sbjct: 310 EVEGLEGKLQSQVENNQALSLLSKEQKQRLQEQEEMLREQEAQRVREQERLCEQNERLRE 369

Query: 130 ENKKLSEQLQ--QKIENDQQHQAAELECEEDVIPDSPITAFSFSGVNRLRRKENPHVRYI 187
           + K L EQ +  +K E   + Q   L  EE+ +       +      RL +K        
Sbjct: 370 QQKTLQEQGERLRKQEQRLRKQEERLRKEEERLQKQEKRLWDQE--ERLWKK-------- 419

Query: 188 EQTHTKLEHSVCANEMRKVSKSSTHPQ------HNPNENEILVADTYDQSQSPMAKAH-G 240
           E+   K E  +  ++  K+ K    PQ      +N  ++ + +     + Q  + + H  
Sbjct: 420 EERLQKQEERLALSQNHKLDKQLAEPQCSFEDLNNEKKSALQLEQQVKELQEKLDEEHLE 479

Query: 241 TSSYTPDKSSFNLATVVAETLGLGVQ----EESETQGPMSPLGDEL 282
            +S    +    L+ V     G G Q    EE E   P   + ++L
Sbjct: 480 AASQRNQQLETQLSLVALPGEGDGGQHLDSEEEEAPRPTPNIPEDL 525


>gi|17017963 forkhead box P2 isoform I [Homo sapiens]
          Length = 715

 Score = 43.9 bits (102), Expect = 7e-04
 Identities = 24/120 (20%), Positives = 63/120 (52%)

Query: 41  KVTKLKQERILDAQRLEEFFTKNQQLREQQKVLHETIKVLEDRLRAGLCDRCAVTEEHMR 100
           ++ ++ Q+++L  Q+L+    + Q +  QQ+ L E  K  +++L   L  +    ++  +
Sbjct: 103 QMQQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFYKKQQEQLHLQLLQQQQQQQQQQQ 162

Query: 101 KKQQEFENIRQQNLKLITELMNERNTLQEENKKLSEQLQQKIENDQQHQAAELECEEDVI 160
           ++QQ+ +  +QQ  +   +   ++   Q+   K +++ QQ+ +  QQ  A +L  ++ ++
Sbjct: 163 QQQQQQQQQQQQQQQQQQQQQQQQQQQQQHPGKQAKEQQQQQQQQQQLAAQQLVFQQQLL 222



 Score = 30.4 bits (67), Expect = 7.7
 Identities = 23/98 (23%), Positives = 52/98 (53%), Gaps = 9/98 (9%)

Query: 64  QQLREQQKVLHETIKVLEDRLRAGLCDRCAVTEEHMRKKQQEFENIRQQNLKLITELMNE 123
           QQ+ +QQ +  + ++ L  + +A +  +  + E +  KKQQE     Q +L+L+ +   +
Sbjct: 105 QQILQQQVLSPQQLQALLQQQQAVMLQQQQLQEFY--KKQQE-----QLHLQLLQQQQQQ 157

Query: 124 RNTLQEENKKLSEQLQQKIENDQQHQAAELECEEDVIP 161
           +   Q++ ++  +Q QQ+ +  QQ Q  + + ++   P
Sbjct: 158 QQ--QQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHP 193


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.310    0.127    0.359 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 36,060,585
Number of Sequences: 37866
Number of extensions: 1742059
Number of successful extensions: 8583
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 61
Number of HSP's successfully gapped in prelim test: 588
Number of HSP's that attempted gapping in prelim test: 6813
Number of HSP's gapped (non-prelim): 2141
length of query: 897
length of database: 18,247,518
effective HSP length: 111
effective length of query: 786
effective length of database: 14,044,392
effective search space: 11038892112
effective search space used: 11038892112
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 67 (30.4 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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