Search of human proteins with 4505353

Search of human proteins with 4505353

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4505353 heparan glucosaminyl
N-deacetylase/N-sulfotransferase 2 [Homo sapiens]
         (883 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4505353 heparan glucosaminyl N-deacetylase/N-sulfotransferase...  1830   0.0  
gi|4505351 N-deacetylase/N-sulfotransferase (heparan glucosaminy...  1316   0.0  
gi|12007650 heparan sulfate N-deacetylase/N-sulfotransferase 4 [...  1254   0.0  
gi|4758766 N-deacetylase/N-sulfotransferase (heparan glucosaminy...  1232   0.0  
gi|45267824 heparan sulfate (glucosamine) 3-O-sulfotransferase 5...   128   3e-29
gi|5174463 heparan sulfate D-glucosaminyl  3-O-sulfotransferase ...   128   3e-29
gi|104876423 heparan sulfate D-glucosaminyl 3-O-sulfotransferase...   123   7e-28
gi|5174467 heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3...   122   1e-27
gi|5174465 heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3...   122   2e-27
gi|4826764 heparan sulfate D-glucosaminyl 3-O-sulfotransferase 1...   120   6e-27
gi|116089312 heparan sulfate (glucosamine) 3-O-sulfotransferase ...   118   2e-26
gi|45505173 B cell RAG associated protein [Homo sapiens]               45   4e-04
gi|122937321 UNC homeobox [Homo sapiens]                               41   0.006
gi|206597445 alpha 1 type XVIII collagen isoform 3 precursor [Ho...    40   0.012
gi|110611233 alpha 1 type XVIII collagen isoform 2 precursor [Ho...    40   0.012
gi|110611235 alpha 1 type XVIII collagen isoform 1 precursor [Ho...    40   0.012
gi|46909600 a disintegrin and metalloproteinase domain 15 isofor...    39   0.016
gi|46909598 a disintegrin and metalloproteinase domain 15 isofor...    39   0.016
gi|46909596 a disintegrin and metalloproteinase domain 15 isofor...    39   0.016
gi|46909594 a disintegrin and metalloproteinase domain 15 isofor...    39   0.016
gi|46909590 a disintegrin and metalloproteinase domain 15 isofor...    39   0.016
gi|45935385 SAM and SH3 domain containing 1 [Homo sapiens]             38   0.036
gi|21389567 chemokine-like factor superfamily 2 [Homo sapiens]         37   0.062
gi|38194229 kelch-like 17 [Homo sapiens]                               37   0.062
gi|56847626 sulfotransferase family, cytosolic, 1C, member 3 [Ho...    36   0.18 
gi|157649073 adenylyl cyclase-associated protein [Homo sapiens]        35   0.24 
gi|5453595 adenylyl cyclase-associated protein [Homo sapiens]          35   0.24 
gi|170650694 centaurin, gamma 1 isoform PIKE-L [Homo sapiens]          35   0.31 
gi|157168329 formin 1 [Homo sapiens]                                   35   0.40 
gi|10863899 numb homolog (Drosophila)-like [Homo sapiens]              35   0.40 

>gi|4505353 heparan glucosaminyl N-deacetylase/N-sulfotransferase 2
           [Homo sapiens]
          Length = 883

 Score = 1830 bits (4740), Expect = 0.0
 Identities = 883/883 (100%), Positives = 883/883 (100%)

Query: 1   MLQLWKVVRPARQLELHRLILLLIAFSLGSMGFLAYYVSTSPKAKEPLPLPLGDCSSGGA 60
           MLQLWKVVRPARQLELHRLILLLIAFSLGSMGFLAYYVSTSPKAKEPLPLPLGDCSSGGA
Sbjct: 1   MLQLWKVVRPARQLELHRLILLLIAFSLGSMGFLAYYVSTSPKAKEPLPLPLGDCSSGGA 60

Query: 61  AGPGPARPPVPPRPPRPPETARTEPVVLVFVESAYSQLGQEIVAILESSRFRYSTELAPG 120
           AGPGPARPPVPPRPPRPPETARTEPVVLVFVESAYSQLGQEIVAILESSRFRYSTELAPG
Sbjct: 61  AGPGPARPPVPPRPPRPPETARTEPVVLVFVESAYSQLGQEIVAILESSRFRYSTELAPG 120

Query: 121 RGDMPTLTDNTHGRYVLVIYENLLKYVNLDAWSRELLDRYCVEYGVGIIGFFRAHEHSLL 180
           RGDMPTLTDNTHGRYVLVIYENLLKYVNLDAWSRELLDRYCVEYGVGIIGFFRAHEHSLL
Sbjct: 121 RGDMPTLTDNTHGRYVLVIYENLLKYVNLDAWSRELLDRYCVEYGVGIIGFFRAHEHSLL 180

Query: 181 SAQLKGFPLFLHSNLGLRDYQVNPSAPLLHLTRPSRLEPGPLPGDDWTIFQSNHSTYEPV 240
           SAQLKGFPLFLHSNLGLRDYQVNPSAPLLHLTRPSRLEPGPLPGDDWTIFQSNHSTYEPV
Sbjct: 181 SAQLKGFPLFLHSNLGLRDYQVNPSAPLLHLTRPSRLEPGPLPGDDWTIFQSNHSTYEPV 240

Query: 241 LLASLRPAEPAVPGPVLRRARLPTVVQDLGLHDGIQRVLFGHGLSFWLHKLIFVDAVAYL 300
           LLASLRPAEPAVPGPVLRRARLPTVVQDLGLHDGIQRVLFGHGLSFWLHKLIFVDAVAYL
Sbjct: 241 LLASLRPAEPAVPGPVLRRARLPTVVQDLGLHDGIQRVLFGHGLSFWLHKLIFVDAVAYL 300

Query: 301 TGKRLCLDLDRYILVDIDDIFVGKEGTRMKVADVEALLTTQNKLRTLVPNFTFNLGFSGK 360
           TGKRLCLDLDRYILVDIDDIFVGKEGTRMKVADVEALLTTQNKLRTLVPNFTFNLGFSGK
Sbjct: 301 TGKRLCLDLDRYILVDIDDIFVGKEGTRMKVADVEALLTTQNKLRTLVPNFTFNLGFSGK 360

Query: 361 FYHTGTEEEDAGDDMLLKHRKEFWWFPHMWSHMQPHLFHNRSVLADQMRLNKQFALEHGI 420
           FYHTGTEEEDAGDDMLLKHRKEFWWFPHMWSHMQPHLFHNRSVLADQMRLNKQFALEHGI
Sbjct: 361 FYHTGTEEEDAGDDMLLKHRKEFWWFPHMWSHMQPHLFHNRSVLADQMRLNKQFALEHGI 420

Query: 421 PTDLGYAVAPHHSGVYPIHTQLYEAWKSVWGIQVTSTEEYPHLRPARYRRGFIHNGIMVL 480
           PTDLGYAVAPHHSGVYPIHTQLYEAWKSVWGIQVTSTEEYPHLRPARYRRGFIHNGIMVL
Sbjct: 421 PTDLGYAVAPHHSGVYPIHTQLYEAWKSVWGIQVTSTEEYPHLRPARYRRGFIHNGIMVL 480

Query: 481 PRQTCGLFTHTIFYNEYPGGSRELDRSIRGGELFLTVLLNPISIFMTHLSNYGNDRLGLY 540
           PRQTCGLFTHTIFYNEYPGGSRELDRSIRGGELFLTVLLNPISIFMTHLSNYGNDRLGLY
Sbjct: 481 PRQTCGLFTHTIFYNEYPGGSRELDRSIRGGELFLTVLLNPISIFMTHLSNYGNDRLGLY 540

Query: 541 TFESLVRFLQCWTRLRLQTLPPVPLAQKYFELFPQERSPLWQNPCDDKRHKDIWSKEKTC 600
           TFESLVRFLQCWTRLRLQTLPPVPLAQKYFELFPQERSPLWQNPCDDKRHKDIWSKEKTC
Sbjct: 541 TFESLVRFLQCWTRLRLQTLPPVPLAQKYFELFPQERSPLWQNPCDDKRHKDIWSKEKTC 600

Query: 601 DRLPKFLIVGPQKTGTTAIHFFLSLHPAVTSSFPSPSTFEEIQFFNSPNYHKGIDWYMDF 660
           DRLPKFLIVGPQKTGTTAIHFFLSLHPAVTSSFPSPSTFEEIQFFNSPNYHKGIDWYMDF
Sbjct: 601 DRLPKFLIVGPQKTGTTAIHFFLSLHPAVTSSFPSPSTFEEIQFFNSPNYHKGIDWYMDF 660

Query: 661 FPVPSNASTDFLFEKSATYFDSEVVPRRGAALLPRAKIITVLTNPADRAYSWYQHQRAHG 720
           FPVPSNASTDFLFEKSATYFDSEVVPRRGAALLPRAKIITVLTNPADRAYSWYQHQRAHG
Sbjct: 661 FPVPSNASTDFLFEKSATYFDSEVVPRRGAALLPRAKIITVLTNPADRAYSWYQHQRAHG 720

Query: 721 DPVALNYTFYQVISASSQTPLALRSLQNRCLVPGYYSTHLQRWLTYYPSGQLLIVDGQEL 780
           DPVALNYTFYQVISASSQTPLALRSLQNRCLVPGYYSTHLQRWLTYYPSGQLLIVDGQEL
Sbjct: 721 DPVALNYTFYQVISASSQTPLALRSLQNRCLVPGYYSTHLQRWLTYYPSGQLLIVDGQEL 780

Query: 781 RTNPAASMESIQKFLGITPFLNYTRTLRFDDDKGFWCQGLEGGKTRCLGRSKGRRYPDMD 840
           RTNPAASMESIQKFLGITPFLNYTRTLRFDDDKGFWCQGLEGGKTRCLGRSKGRRYPDMD
Sbjct: 781 RTNPAASMESIQKFLGITPFLNYTRTLRFDDDKGFWCQGLEGGKTRCLGRSKGRRYPDMD 840

Query: 841 TESRLFLTDFFRNHNLELSKLLSRLGQPVPSWLREELQHSSLG 883
           TESRLFLTDFFRNHNLELSKLLSRLGQPVPSWLREELQHSSLG
Sbjct: 841 TESRLFLTDFFRNHNLELSKLLSRLGQPVPSWLREELQHSSLG 883


>gi|4505351 N-deacetylase/N-sulfotransferase (heparan glucosaminyl)
           1 [Homo sapiens]
          Length = 882

 Score = 1316 bits (3407), Expect = 0.0
 Identities = 621/879 (70%), Positives = 735/879 (83%), Gaps = 13/879 (1%)

Query: 9   RPARQLELHRLILLLIAFSLGSMGFLAYYVSTSPKAKEP-LPLPLGDCSSGGAAGPGPAR 67
           R  R +    ++ LL  F L S+   AYY+    +  EP    P  DC       P P  
Sbjct: 9   RLCRHVSPQAVLFLLFIFCLFSVFISAYYLYGWKRGLEPSADAPEPDCGD-----PPPVA 63

Query: 68  PP--VPPRPPRPPETARTEPVVLVFVESAYSQLGQEIVAILESSRFRYSTELAPGRGDMP 125
           P   +P +P +    +RT+P+VLVFVES YSQLGQE+VAILESSRF+Y TE+APG+GDMP
Sbjct: 64  PSRLLPLKPVQAATPSRTDPLVLVFVESLYSQLGQEVVAILESSRFKYRTEIAPGKGDMP 123

Query: 126 TLTDNTHGRYVLVIYENLLKYVNLDAWSRELLDRYCVEYGVGIIGFFRAHEHSLLSAQLK 185
           TLTD   GR+ L+IYEN+LKYVNLDAW+RELLD+YCV YGVGIIGFF+A+E+SLLSAQLK
Sbjct: 124 TLTDKGRGRFALIIYENILKYVNLDAWNRELLDKYCVAYGVGIIGFFKANENSLLSAQLK 183

Query: 186 GFPLFLHSNLGLRDYQVNPSAPLLHLTRPSRLEPGPLPGDDWTIFQSNHSTYEPVLLASL 245
           GFPLFLHSNLGL+D  +NP +PLL++TRPS +E G LPG+DWT+FQSNHSTYEPVLLA  
Sbjct: 184 GFPLFLHSNLGLKDCSINPKSPLLYVTRPSEVEKGVLPGEDWTVFQSNHSTYEPVLLAKT 243

Query: 246 RPAEPAVP----GPVLRRARLPTVVQDLGLHDGIQRVLFGHGLSFWLHKLIFVDAVAYLT 301
           R +E ++P       L  A   TVVQDLGLHDGIQRVLFG+ L+FWLHKL+FVDAVA+LT
Sbjct: 244 RSSE-SIPHLGADAGLHAALHATVVQDLGLHDGIQRVLFGNNLNFWLHKLVFVDAVAFLT 302

Query: 302 GKRLCLDLDRYILVDIDDIFVGKEGTRMKVADVEALLTTQNKLRTLVPNFTFNLGFSGKF 361
           GKRL L LDRYILVDIDDIFVGKEGTRMKV DV+AL  TQN+LR  +PNFTFNLG+SGKF
Sbjct: 303 GKRLSLPLDRYILVDIDDIFVGKEGTRMKVEDVKALFDTQNELRAHIPNFTFNLGYSGKF 362

Query: 362 YHTGTEEEDAGDDMLLKHRKEFWWFPHMWSHMQPHLFHNRSVLADQMRLNKQFALEHGIP 421
           +HTGT  EDAGDD+LL + KEFWWFPHMWSHMQPHLFHN+SVLA+QM LNK+FA+EHGIP
Sbjct: 363 FHTGTNAEDAGDDLLLSYVKEFWWFPHMWSHMQPHLFHNQSVLAEQMALNKKFAVEHGIP 422

Query: 422 TDLGYAVAPHHSGVYPIHTQLYEAWKSVWGIQVTSTEEYPHLRPARYRRGFIHNGIMVLP 481
           TD+GYAVAPHHSGVYP+H QLYEAWK VW I+VTSTEEYPHL+PARYRRGFIHNGIMVLP
Sbjct: 423 TDMGYAVAPHHSGVYPVHVQLYEAWKQVWSIRVTSTEEYPHLKPARYRRGFIHNGIMVLP 482

Query: 482 RQTCGLFTHTIFYNEYPGGSRELDRSIRGGELFLTVLLNPISIFMTHLSNYGNDRLGLYT 541
           RQTCGLFTHTIFYNEYPGGS ELD+ I GGELFLTVLLNPISIFMTHLSNYGNDRLGLYT
Sbjct: 483 RQTCGLFTHTIFYNEYPGGSSELDKIINGGELFLTVLLNPISIFMTHLSNYGNDRLGLYT 542

Query: 542 FESLVRFLQCWTRLRLQTLPPVPLAQKYFELFPQERSPLWQNPCDDKRHKDIWSKEKTCD 601
           F+ LVRFL  WT LRLQTLPPV LAQKYF++F +E+ PLWQ+PC+DKRHKDIWSKEKTCD
Sbjct: 543 FKHLVRFLHSWTNLRLQTLPPVQLAQKYFQIFSEEKDPLWQDPCEDKRHKDIWSKEKTCD 602

Query: 602 RLPKFLIVGPQKTGTTAIHFFLSLHPAVTSSFPSPSTFEEIQFFNSPNYHKGIDWYMDFF 661
           R PK LI+GPQKTGTTA++ FL +HP ++S++PS  TFEEIQFFN  NYHKGIDWYM+FF
Sbjct: 603 RFPKLLIIGPQKTGTTALYLFLGMHPDLSSNYPSSETFEEIQFFNGHNYHKGIDWYMEFF 662

Query: 662 PVPSNASTDFLFEKSATYFDSEVVPRRGAALLPRAKIITVLTNPADRAYSWYQHQRAHGD 721
           P+PSN ++DF FEKSA YFDSEV PRR AALLP+AK++T+L NPADRAYSWYQHQRAH D
Sbjct: 663 PIPSNTTSDFYFEKSANYFDSEVAPRRAAALLPKAKVLTILINPADRAYSWYQHQRAHDD 722

Query: 722 PVALNYTFYQVISASSQTPLALRSLQNRCLVPGYYSTHLQRWLTYYPSGQLLIVDGQELR 781
           PVAL YTF++VI+A S     LR+LQNRCLVPG+Y+TH++RWL+ Y + Q+L++DG+ LR
Sbjct: 723 PVALKYTFHEVITAGSDASSKLRALQNRCLVPGWYATHIERWLSAYHANQILVLDGKLLR 782

Query: 782 TNPAASMESIQKFLGITPFLNYTRTLRFDDDKGFWCQGLEGGKTRCLGRSKGRRYPDMDT 841
           T PA  M+ +QKFLG+T  ++Y +TL FD  KGFWCQ LEGGKT+CLG+SKGR+YP+MD 
Sbjct: 783 TEPAKVMDMVQKFLGVTNTIDYHKTLAFDPKKGFWCQLLEGGKTKCLGKSKGRKYPEMDL 842

Query: 842 ESRLFLTDFFRNHNLELSKLLSRLGQPVPSWLREELQHS 880
           +SR FL D++R+HN+ELSKLL ++GQ +P+WLRE+LQ++
Sbjct: 843 DSRAFLKDYYRDHNIELSKLLYKMGQTLPTWLREDLQNT 881


>gi|12007650 heparan sulfate N-deacetylase/N-sulfotransferase 4
           [Homo sapiens]
          Length = 872

 Score = 1254 bits (3246), Expect = 0.0
 Identities = 587/862 (68%), Positives = 709/862 (82%), Gaps = 8/862 (0%)

Query: 19  LILLLIAFSLGSMGFLAYYVSTSPKAKEPL--PLPLGDCSSGGAAGPGPARPPVPPRPPR 76
           LI+LL  F L S+   AY++ +  K +  L       +C+        P R  +  +  +
Sbjct: 14  LIVLLATFCLVSIVISAYFLYSGYKQEMTLIETTAEAECTDIKIL---PYRS-MELKTVK 69

Query: 77  PPETARTEPVVLVFVESAYSQLGQEIVAILESSRFRYSTELAPGRGDMPTLTDNTHGRYV 136
           P +T++T+P VL+FVES YSQLGQ+I+AILESSRF+Y   +APG+GD+P LTDN  G+Y 
Sbjct: 70  PIDTSKTDPTVLLFVESQYSQLGQDIIAILESSRFQYHMVIAPGKGDIPPLTDNGKGKYT 129

Query: 137 LVIYENLLKYVNLDAWSRELLDRYCVEYGVGIIGFFRAHEHSLLSAQLKGFPLFLHSNLG 196
           LVIYEN+LKYV++D+W+RELL++YCVEY V IIGF +A+E+SL S QLKGFPL L +NL 
Sbjct: 130 LVIYENILKYVSMDSWNRELLEKYCVEYSVSIIGFHKANENSLPSTQLKGFPLNLFNNLA 189

Query: 197 LRDYQVNPSAPLLHLTRPSRLEPGPLPGDDWTIFQSNHSTYEPVLLASLRPAEPAVPGPV 256
           L+D  VNP +PLLH+T+  ++E GPLPG+DWTIFQ NHSTY+PVLL  L+  +      +
Sbjct: 190 LKDCFVNPQSPLLHITKAPKVEKGPLPGEDWTIFQYNHSTYQPVLLTELQTEKSL--SSL 247

Query: 257 LRRARLPTVVQDLGLHDGIQRVLFGHGLSFWLHKLIFVDAVAYLTGKRLCLDLDRYILVD 316
             +    TV+QDLGLHDGIQRVLFG+ L+FWLHKLIF+DA+++L+GKRL L LDRYILVD
Sbjct: 248 SSKTLFATVIQDLGLHDGIQRVLFGNNLNFWLHKLIFIDAISFLSGKRLTLSLDRYILVD 307

Query: 317 IDDIFVGKEGTRMKVADVEALLTTQNKLRTLVPNFTFNLGFSGKFYHTGTEEEDAGDDML 376
           IDDIFVGKEGTRM V DV+ALL TQN LRT V NFTFNLGFSGKFYHTGTEEED GDD+L
Sbjct: 308 IDDIFVGKEGTRMNVKDVKALLETQNLLRTQVANFTFNLGFSGKFYHTGTEEEDEGDDLL 367

Query: 377 LKHRKEFWWFPHMWSHMQPHLFHNRSVLADQMRLNKQFALEHGIPTDLGYAVAPHHSGVY 436
           L+   EFWWFPHMWSHMQPHLFHN S L +QM LNK+FALEHGIP ++GYAVAPHHSGVY
Sbjct: 368 LRSVDEFWWFPHMWSHMQPHLFHNESSLVEQMILNKEFALEHGIPINMGYAVAPHHSGVY 427

Query: 437 PIHTQLYEAWKSVWGIQVTSTEEYPHLRPARYRRGFIHNGIMVLPRQTCGLFTHTIFYNE 496
           P+H QLY AWK VWGIQVTSTEEYPHL+PARYR+GFIHN IMVLPRQTCGLFTHTIFY E
Sbjct: 428 PVHIQLYAAWKKVWGIQVTSTEEYPHLKPARYRKGFIHNSIMVLPRQTCGLFTHTIFYKE 487

Query: 497 YPGGSRELDRSIRGGELFLTVLLNPISIFMTHLSNYGNDRLGLYTFESLVRFLQCWTRLR 556
           YPGG +ELD+SIRGGELFLT+LLNPISIFMTHLSNYGNDRLGLYTF +LV F+Q WT L+
Sbjct: 488 YPGGPQELDKSIRGGELFLTILLNPISIFMTHLSNYGNDRLGLYTFVNLVNFVQSWTNLK 547

Query: 557 LQTLPPVPLAQKYFELFPQERSPLWQNPCDDKRHKDIWSKEKTCDRLPKFLIVGPQKTGT 616
           LQTLPPV LA +YFELFP+++ PLWQNPCDDKRHKDIWS+EKTCD LPKFL++GPQKTGT
Sbjct: 548 LQTLPPVQLAHQYFELFPEQKDPLWQNPCDDKRHKDIWSREKTCDHLPKFLVIGPQKTGT 607

Query: 617 TAIHFFLSLHPAVTSSFPSPSTFEEIQFFNSPNYHKGIDWYMDFFPVPSNASTDFLFEKS 676
           TA++ FL +HP++ S+ PSP TFEE+QFFN  NYHKGIDWYMDFFP PSN ++DFLFEKS
Sbjct: 608 TALYLFLLMHPSIISNLPSPKTFEEVQFFNGNNYHKGIDWYMDFFPTPSNTTSDFLFEKS 667

Query: 677 ATYFDSEVVPRRGAALLPRAKIITVLTNPADRAYSWYQHQRAHGDPVALNYTFYQVISAS 736
           A YF SE  PRR A+L+P+AKIIT+L +P+DRAYSWYQHQR+H DP AL + FY+VIS  
Sbjct: 668 ANYFHSEEAPRRAASLVPKAKIITILIDPSDRAYSWYQHQRSHEDPAALRFNFYEVISTG 727

Query: 737 SQTPLALRSLQNRCLVPGYYSTHLQRWLTYYPSGQLLIVDGQELRTNPAASMESIQKFLG 796
              P  L++LQ RCLVPG+Y+ H++RWLTY+ + QLLI+DGQ+LR++PA  M+ +QKFLG
Sbjct: 728 HWAPSDLKTLQRRCLVPGWYAVHIERWLTYFATSQLLIIDGQQLRSDPATVMDEVQKFLG 787

Query: 797 ITPFLNYTRTLRFDDDKGFWCQGLEGGKTRCLGRSKGRRYPDMDTESRLFLTDFFRNHNL 856
           +TP  NY+  L FD  KGFWCQ LEGGKT+CLG+SKGR+YP MD ESR FL++++R+HN+
Sbjct: 788 VTPRYNYSEALTFDPQKGFWCQLLEGGKTKCLGKSKGRKYPPMDPESRTFLSNYYRDHNV 847

Query: 857 ELSKLLSRLGQPVPSWLREELQ 878
           ELSKLL RLGQP+PSWLR+ELQ
Sbjct: 848 ELSKLLHRLGQPLPSWLRQELQ 869


>gi|4758766 N-deacetylase/N-sulfotransferase (heparan glucosaminyl)
           3 [Homo sapiens]
          Length = 873

 Score = 1232 bits (3188), Expect = 0.0
 Identities = 567/861 (65%), Positives = 693/861 (80%), Gaps = 3/861 (0%)

Query: 18  RLILLLIAFSLGSMGFLAYYVSTSPKAKEPLPLPLGDCSSGGAAGPGPARPPVPPRPPRP 77
           R ++LL  F + S+   AYY+ +  K +  L     +   G           V  +  + 
Sbjct: 13  RTVILLATFCMVSIIISAYYLYSGYKQENELSETASEVDCGDLQHLPYQLMEV--KAMKL 70

Query: 78  PETARTEPVVLVFVESAYSQLGQEIVAILESSRFRYSTELAPGRGDMPTLTDNTHGRYVL 137
            + +RT+P VLVFVES YS LGQ+I+ ILESSRF+Y  E+APG+GD+P L D   G+Y+L
Sbjct: 71  FDASRTDPTVLVFVESQYSSLGQDIIMILESSRFQYHIEIAPGKGDLPVLIDKMKGKYIL 130

Query: 138 VIYENLLKYVNLDAWSRELLDRYCVEYGVGIIGFFRAHEHSLLSAQLKGFPLFLHSNLGL 197
           +IYEN+LKY+N+D+W+R LLD+YCVEYGVG+IGF +  E S+ S QLKGFP  ++ NL +
Sbjct: 131 IIYENILKYINMDSWNRSLLDKYCVEYGVGVIGFHKTSEKSVQSFQLKGFPFSIYGNLAV 190

Query: 198 RDYQVNPSAPLLHLTRPSRLEPGPLPGDDWTIFQSNHSTYEPVLLASLRPAEPAVPGPVL 257
           +D  +NP +PL+ +T+ S+LE G LPG DWT+FQ NHS Y+PV+ A ++  E   P  + 
Sbjct: 191 KDCCINPHSPLIRVTKSSKLEKGSLPGTDWTVFQINHSAYQPVIFAKVKTPENLSPS-IS 249

Query: 258 RRARLPTVVQDLGLHDGIQRVLFGHGLSFWLHKLIFVDAVAYLTGKRLCLDLDRYILVDI 317
           + A   T++ DLGLHDGIQRVLFG+ L+FWLHKLIF+DA+++L+GKRL L LDRYILVDI
Sbjct: 250 KGAFYATIIHDLGLHDGIQRVLFGNNLNFWLHKLIFIDAISFLSGKRLTLSLDRYILVDI 309

Query: 318 DDIFVGKEGTRMKVADVEALLTTQNKLRTLVPNFTFNLGFSGKFYHTGTEEEDAGDDMLL 377
           DDIFVGKEGTRM   DV+ALL TQN LR  + NFTFNLGFSGKFYHTGTEEED GDD LL
Sbjct: 310 DDIFVGKEGTRMNTNDVKALLDTQNLLRAQITNFTFNLGFSGKFYHTGTEEEDEGDDCLL 369

Query: 378 KHRKEFWWFPHMWSHMQPHLFHNRSVLADQMRLNKQFALEHGIPTDLGYAVAPHHSGVYP 437
               EFWWFPHMWSHMQPHLFHN S L +QM LNK+FALEHGIPTD+GYAVAPHHSGVYP
Sbjct: 370 GSVDEFWWFPHMWSHMQPHLFHNESSLVEQMILNKKFALEHGIPTDMGYAVAPHHSGVYP 429

Query: 438 IHTQLYEAWKSVWGIQVTSTEEYPHLRPARYRRGFIHNGIMVLPRQTCGLFTHTIFYNEY 497
           +H QLYEAWK VW I++TSTEEYPHL+PARYRRGFIH  IMVLPRQTCGLFTHTIFY EY
Sbjct: 430 VHVQLYEAWKKVWNIKITSTEEYPHLKPARYRRGFIHKNIMVLPRQTCGLFTHTIFYKEY 489

Query: 498 PGGSRELDRSIRGGELFLTVLLNPISIFMTHLSNYGNDRLGLYTFESLVRFLQCWTRLRL 557
           PGG +ELD+SI+GGELF TV+LNPISIFMTHLSNYGNDRLGLYTF +L  F++ WT LRL
Sbjct: 490 PGGPKELDKSIQGGELFFTVVLNPISIFMTHLSNYGNDRLGLYTFVNLANFVKSWTNLRL 549

Query: 558 QTLPPVPLAQKYFELFPQERSPLWQNPCDDKRHKDIWSKEKTCDRLPKFLIVGPQKTGTT 617
           QTLPPV LA KYFELFP ++ PLWQNPCDDKRH+DIWSKEKTCDRLPKFL++GPQKTGTT
Sbjct: 550 QTLPPVQLAHKYFELFPDQKDPLWQNPCDDKRHRDIWSKEKTCDRLPKFLVIGPQKTGTT 609

Query: 618 AIHFFLSLHPAVTSSFPSPSTFEEIQFFNSPNYHKGIDWYMDFFPVPSNASTDFLFEKSA 677
           A++ FL +HP++ S+ PSP TFEE+QFFN  NYH+GIDWYMDFFPVPSN +TDFLFEKSA
Sbjct: 610 ALYLFLVMHPSILSNSPSPKTFEEVQFFNRNNYHRGIDWYMDFFPVPSNVTTDFLFEKSA 669

Query: 678 TYFDSEVVPRRGAALLPRAKIITVLTNPADRAYSWYQHQRAHGDPVALNYTFYQVISASS 737
            YF SE  P+R A+L+P+AKIIT+L +P+DRAYSWYQHQR+H DP AL ++FY+VISA  
Sbjct: 670 NYFHSEEAPKRAASLVPKAKIITILIDPSDRAYSWYQHQRSHEDPAALKFSFYEVISAGP 729

Query: 738 QTPLALRSLQNRCLVPGYYSTHLQRWLTYYPSGQLLIVDGQELRTNPAASMESIQKFLGI 797
           + P  LR+LQ RCLVPG+Y++H++RWL Y+P  QLLI+DGQ+LRT+PA  M+ +QKFLG+
Sbjct: 730 RAPSELRALQKRCLVPGWYASHIERWLVYFPPFQLLIIDGQQLRTDPATVMDEVQKFLGV 789

Query: 798 TPFLNYTRTLRFDDDKGFWCQGLEGGKTRCLGRSKGRRYPDMDTESRLFLTDFFRNHNLE 857
            P  NY+  L FD  KGFWCQ LE GKT+CLG+SKGR+YP MD++SR FL+ ++R+HN+E
Sbjct: 790 LPHYNYSEALTFDSHKGFWCQLLEEGKTKCLGKSKGRKYPPMDSDSRTFLSSYYRDHNVE 849

Query: 858 LSKLLSRLGQPVPSWLREELQ 878
           LSKLL +LGQP+PSWLR+ELQ
Sbjct: 850 LSKLLHKLGQPLPSWLRQELQ 870


>gi|45267824 heparan sulfate (glucosamine) 3-O-sulfotransferase 5
           [Homo sapiens]
          Length = 346

 Score =  128 bits (321), Expect = 3e-29
 Identities = 85/264 (32%), Positives = 130/264 (49%), Gaps = 12/264 (4%)

Query: 602 RLPKFLIVGPQKTGTTAIHFFLSLHPAVTSSFPSPSTFEEIQFF-NSPNYHKGIDWYMDF 660
           +LPK +I+G +K GT A+   L+LHPAV  +       +EI FF N  NY KGI+WY   
Sbjct: 89  QLPKAIIIGVRKGGTRALLEMLNLHPAVVKAS------QEIHFFDNDENYGKGIEWYRK- 141

Query: 661 FPVPSNASTDFLFEKSATYFDSEVVPRRGAALLPRAKIITVLTNPADRAYSWYQHQRAHG 720
             +P +       EKS  YF +E VP R   +    K++ ++  P  RA S Y  Q   G
Sbjct: 142 -KMPFSYPQQITIEKSPAYFITEEVPERIYKMNSSIKLLIIVREPTTRAISDYT-QVLEG 199

Query: 721 DPVALNYTFYQVISASSQTPLALRSLQNRCLVPGYYSTHLQRWLTYYPSGQLLIVDGQEL 780
                N T+Y+    +        + + + +    Y+ HL+RWL Y+P  Q  +VDG  L
Sbjct: 200 KE-RKNKTYYKFEKLAIDPNTCEVNTKYKAVRTSIYTKHLERWLKYFPIEQFHVVDGDRL 258

Query: 781 RTNPAASMESIQKFLGITPFLNYTRTLRFDDDKGFWCQGLEGGKTRCLGRSKGRRYPDMD 840
            T P   ++ ++KFL + P ++    L F+  +GF+C        +CL  SKGR +P++D
Sbjct: 259 ITEPLPELQLVEKFLNLPPRIS-QYNLYFNATRGFYCLRFNIIFNKCLAGSKGRIHPEVD 317

Query: 841 TESRLFLTDFFRNHNLELSKLLSR 864
                 L  FF   N +  ++  R
Sbjct: 318 PSVITKLRKFFHPFNQKFYQITGR 341


>gi|5174463 heparan sulfate D-glucosaminyl  3-O-sulfotransferase 2
           [Homo sapiens]
          Length = 367

 Score =  128 bits (321), Expect = 3e-29
 Identities = 85/258 (32%), Positives = 129/258 (50%), Gaps = 17/258 (6%)

Query: 602 RLPKFLIVGPQKTGTTAIHFFLSLHPAVTSSFPSPSTFEEIQFFNSPNYHKGIDWYMDFF 661
           RLP+ LIVG +K GT A+  F+ +HP V +    P  F+        NY +G+DWY    
Sbjct: 113 RLPQALIVGVKKGGTRAVLEFIRVHPDVRALGTEPHFFDR-------NYGRGLDWYRSL- 164

Query: 662 PVPSNASTDFLFEKSATYFDSEVVPRRGAALLPRAKIITVLTNPADRAYSWYQHQRAHGD 721
            +P    +    EK+ +YF ++  PRR   +    K+I V+ NP  RA S Y    +   
Sbjct: 165 -MPRTLESQITLEKTPSYFVTQEAPRRIFNMSRDTKLIVVVRNPVTRAISDYTQTLSKKP 223

Query: 722 PVALNYTFYQVISASSQTPLALRSLQNRCLVPGYYSTHLQRWLTYYPSGQLLIVDGQELR 781
            +      ++ +S  ++T L L  +    +  G Y  HL+ WL Y+P  Q+  V G+ L 
Sbjct: 224 DIPT----FEGLSFRNRT-LGLVDVSWNAIRIGMYVLHLESWLQYFPLAQIHFVSGERLI 278

Query: 782 TNPAASMESIQKFLGITPFLNYTRTLRFDDDKGFWCQGLEGGK--TRCLGRSKGRRYPDM 839
           T+PA  M  +Q FLGI  F+   +   F+  KGF C          RCLG+SKGR +  +
Sbjct: 279 TDPAGEMGRVQDFLGIKRFIT-DKHFYFNKTKGFPCLKKTESSLLPRCLGKSKGRTHVQI 337

Query: 840 DTESRLFLTDFFRNHNLE 857
           D E    L +F+R +N++
Sbjct: 338 DPEVIDQLREFYRPYNIK 355


>gi|104876423 heparan sulfate D-glucosaminyl 3-O-sulfotransferase 4
           [Homo sapiens]
          Length = 456

 Score =  123 bits (309), Expect = 7e-28
 Identities = 83/277 (29%), Positives = 136/277 (49%), Gaps = 21/277 (7%)

Query: 602 RLPKFLIVGPQKTGTTAIHFFLSLHPAVTSSFPSPSTFEEIQFFNSPNYHKGIDWYMDFF 661
           +LP+ LI+G +K GT A+   + +HP V +    P  F+        NY KG++WY +  
Sbjct: 196 KLPQALIIGVKKGGTRALLEAIRVHPDVRAVGVEPHFFDR-------NYEKGLEWYRNV- 247

Query: 662 PVPSNASTDFLFEKSATYFDSEVVPRRGAALLPRAKIITVLTNPADRAYSWYQHQRAHGD 721
            +P         EK+ +YF +   P+R  ++    K+I V+ NP  RA S Y    +   
Sbjct: 248 -MPKTLDGQITMEKTPSYFVTNEAPKRIHSMAKDIKLIVVVRNPVTRAISDYTQTLSKKP 306

Query: 722 PVALNYTFYQVISASSQTPLALRSLQNRCLVPGYYSTHLQRWLTYYPSGQLLIVDGQELR 781
            +      ++V++  ++T L L       +  G Y+ HL+ WL Y+P  Q+L V G+ L 
Sbjct: 307 EIPT----FEVLAFKNRT-LGLIDASWSAIRIGIYALHLENWLQYFPLSQILFVSGERLI 361

Query: 782 TNPAASMESIQKFLGITPFLNYTRTLRFDDDKGFWC--QGLEGGKTRCLGRSKGRRYPDM 839
            +PA  M  +Q FLG+   +   +   F+  KGF C  +  +    RCLG+SKGR +P +
Sbjct: 362 VDPAGEMAKVQDFLGLKRVVT-EKHFYFNKTKGFPCLKKPEDSSAPRCLGKSKGRTHPRI 420

Query: 840 DTESRLFLTDFFRNHNLELSKLLSRLGQPVPSWLREE 876
           D +    L  F++  NL   ++  +  Q    W +EE
Sbjct: 421 DPDVIHRLRKFYKPFNLMFYQMTGQDFQ----WEQEE 453


>gi|5174467 heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3B1
           [Homo sapiens]
          Length = 390

 Score =  122 bits (307), Expect = 1e-27
 Identities = 89/312 (28%), Positives = 150/312 (48%), Gaps = 20/312 (6%)

Query: 554 RLRLQTLPPVPLAQKYFELFPQERSPLWQNP--CDDKRHKDIWSKEKTCDRLPKFLIVGP 611
           RL  +  P  PLA    E+     SP  Q+P   D       +       +LP+ +I+G 
Sbjct: 87  RLPFRAPPATPLASGK-EMAEGAASPEEQSPEVPDSPSPISSFFSGSGSKQLPQAIIIGV 145

Query: 612 QKTGTTAIHFFLSLHPAVTSSFPSPSTFEEIQFFNSPNYHKGIDWYMDFFPVPSNASTDF 671
           +K GT A+  FL +HP V +    P  F+        +Y KG+ WY D   +P       
Sbjct: 146 KKGGTRALLEFLRVHPDVRAVGAEPHFFDR-------SYDKGLAWYRDL--MPRTLDGQI 196

Query: 672 LFEKSATYFDSEVVPRRGAALLPRAKIITVLTNPADRAYSWYQHQRAHGDPVALNYTFYQ 731
             EK+ +YF +   P R +A+    K+I V+ +P  RA S Y    +    +      ++
Sbjct: 197 TMEKTPSYFVTREAPARISAMSKDTKLIVVVRDPVTRAISDYTQTLSKRPDIPT----FE 252

Query: 732 VISASSQTPLALRSLQNRCLVPGYYSTHLQRWLTYYPSGQLLIVDGQELRTNPAASMESI 791
            ++  ++T   + +  +   + G Y+ HL+ WL ++P  Q+L V G+ L ++PA  +  +
Sbjct: 253 SLTFKNRTAGLIDTSWSAIQI-GIYAKHLEHWLRHFPIRQMLFVSGERLISDPAGELGRV 311

Query: 792 QKFLGITPFLNYTRTLRFDDDKGFWCQGLEGGKTR--CLGRSKGRRYPDMDTESRLFLTD 849
           Q FLG+   +   +   F+  KGF C     G +R  CLG++KGR +P++D E    L +
Sbjct: 312 QDFLGLKRIIT-DKHFYFNKTKGFPCLKKAEGSSRPHCLGKTKGRTHPEIDREVVRRLRE 370

Query: 850 FFRNHNLELSKL 861
           F+R  NL+  ++
Sbjct: 371 FYRPFNLKFYQM 382


>gi|5174465 heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3A1
           [Homo sapiens]
          Length = 406

 Score =  122 bits (305), Expect = 2e-27
 Identities = 77/262 (29%), Positives = 134/262 (51%), Gaps = 17/262 (6%)

Query: 602 RLPKFLIVGPQKTGTTAIHFFLSLHPAVTSSFPSPSTFEEIQFFNSPNYHKGIDWYMDFF 661
           +LP+ +I+G +K GT A+  FL +HP V +    P  F+        +Y KG+ WY D  
Sbjct: 151 QLPQAIIIGVKKGGTRALLEFLRVHPDVRAVGAEPHFFDR-------SYDKGLAWYRDL- 202

Query: 662 PVPSNASTDFLFEKSATYFDSEVVPRRGAALLPRAKIITVLTNPADRAYSWYQHQRAHGD 721
            +P         EK+ +YF +   P R +A+    K+I V+ +P  RA S Y    +   
Sbjct: 203 -MPRTLDGQITMEKTPSYFVTREAPARISAMSKDTKLIVVVRDPVTRAISDYTQTLSKRP 261

Query: 722 PVALNYTFYQVISASSQTPLALRSLQNRCLVPGYYSTHLQRWLTYYPSGQLLIVDGQELR 781
            +      ++ ++  ++T   + +  +   + G Y+ HL+ WL ++P  Q+L V G+ L 
Sbjct: 262 DIPT----FESLTFKNRTAGLIDTSWSAIQI-GIYAKHLEHWLRHFPIRQMLFVSGERLI 316

Query: 782 TNPAASMESIQKFLGITPFLNYTRTLRFDDDKGFWCQGLEGGKTR--CLGRSKGRRYPDM 839
           ++PA  +  +Q FLG+   +   +   F+  KGF C     G +R  CLG++KGR +P++
Sbjct: 317 SDPAGELGRVQDFLGLKRIIT-DKHFYFNKTKGFPCLKKAEGSSRPHCLGKTKGRTHPEI 375

Query: 840 DTESRLFLTDFFRNHNLELSKL 861
           D E    L +F+R  NL+  ++
Sbjct: 376 DREVVRRLREFYRPFNLKFYQM 397


>gi|4826764 heparan sulfate D-glucosaminyl 3-O-sulfotransferase 1
           precursor [Homo sapiens]
          Length = 307

 Score =  120 bits (301), Expect = 6e-27
 Identities = 78/272 (28%), Positives = 139/272 (51%), Gaps = 25/272 (9%)

Query: 599 TCDRLPKFLIVGPQKTGTTAIHFFLSLHPAVTSSFPSPSTFEEIQFFN-SPNYHKGIDWY 657
           +  +LP+ +I+G +K GT A+   LSLHP V ++        E+ FF+   +Y  G+ WY
Sbjct: 50  SAQQLPQTIIIGVRKGGTRALLEMLSLHPDVAAAE------NEVHFFDWEEHYSHGLGWY 103

Query: 658 MDFFPVPSNASTDFLFEKSATYFDSEVVPRRGAALLPRAKIITVLTNPADRAYS-----W 712
           +    +P +       EK+  YF S  VP R  ++ P  +++ +L +P++R  S     +
Sbjct: 104 LS--QMPFSWPHQLTVEKTPAYFTSPKVPERVYSMNPSIRLLLILRDPSERVLSDYTQVF 161

Query: 713 YQHQRAHGDPVALNYTFYQVISASSQTPLALRSLQNRCLVPGYYSTHLQRWLTYYPSGQL 772
           Y H + H    ++     + +    +  +  ++L NR L    Y  H+Q WL ++P   +
Sbjct: 162 YNHMQKHKPYPSIE----EFLVRDGRLNVDYKAL-NRSL----YHVHMQNWLRFFPLRHI 212

Query: 773 LIVDGQELRTNPAASMESIQKFLGITPFLNYTRTLRFDDDKGFWCQGLEGGKTRCLGRSK 832
            IVDG  L  +P   ++ +++FL ++P +N      F+  KGF+C   + G+ RCL  SK
Sbjct: 213 HIVDGDRLIRDPFPEIQKVERFLKLSPQIN-ASNFYFNKTKGFYCL-RDSGRDRCLHESK 270

Query: 833 GRRYPDMDTESRLFLTDFFRNHNLELSKLLSR 864
           GR +P +D +    L ++F   N +  +L+ R
Sbjct: 271 GRAHPQVDPKLLNKLHEYFHEPNKKFFELVGR 302


>gi|116089312 heparan sulfate (glucosamine) 3-O-sulfotransferase 6
           [Homo sapiens]
          Length = 311

 Score =  118 bits (296), Expect = 2e-26
 Identities = 83/258 (32%), Positives = 118/258 (45%), Gaps = 22/258 (8%)

Query: 602 RLPKFLIVGPQKTGTTAIHFFLSLHPAVTSSFPSPSTFEEIQFFNSPNYHKGIDWYMDFF 661
           R P+ LIVG +K GT A+  FL LHP V +    P  F+         Y +G+ WY    
Sbjct: 58  RFPQALIVGVKKGGTRALLEFLRLHPDVRALGSEPHFFDRC-------YERGLAWYRSL- 109

Query: 662 PVPSNASTDFLFEKSATYFDSEVVPRRGAALLPRAKIITVLTNPADRAYSWYQH--QRAH 719
            +P         EK+ +YF +   PRR  A+ P  K+I V+ NP  RA S Y     +  
Sbjct: 110 -MPRTLDGQITMEKTPSYFVTREAPRRIHAMSPDTKLIVVVRNPVTRAISDYAQTLSKTP 168

Query: 720 GDPVALNYTFYQVISASSQTPLALRSLQNRCLVPGYYSTHLQRWLTYYPSGQLLIVDGQE 779
           G P      F   +        A+R         G Y+ HL  WL Y+P    L V G+ 
Sbjct: 169 GLPSFRALAFRHGLGPVDTAWSAVRI--------GLYAQHLDHWLRYFPLSHFLFVSGER 220

Query: 780 LRTNPAASMESIQKFLGITPFLNYTRTLRFDDDKGFWC--QGLEGGKTRCLGRSKGRRYP 837
           L ++PA  +  +Q FLG+   +   +   F+  KGF C  +   G + RCLG+SKGR +P
Sbjct: 221 LVSDPAGEVGRVQDFLGLKRVVT-DKHFYFNATKGFPCLKKAQGGSRPRCLGKSKGRPHP 279

Query: 838 DMDTESRLFLTDFFRNHN 855
            +       L +F+R  N
Sbjct: 280 RVPQALVRRLQEFYRPFN 297


>gi|45505173 B cell RAG associated protein [Homo sapiens]
          Length = 561

 Score = 44.7 bits (104), Expect = 4e-04
 Identities = 65/312 (20%), Positives = 119/312 (38%), Gaps = 63/312 (20%)

Query: 603 LPKFLIVGPQKTGTTAIHFFLSLHPAVT-SSFPSP-----STFEEIQFFNSPNYHKGIDW 656
           LP F I+G  K GTT ++  L LHP V  S+   P       F  ++  +       ++ 
Sbjct: 253 LPHFYIIGQPKCGTTDLYDRLRLHPEVKFSAIKEPHWWTRKRFGIVRLRDGLRDRYPVED 312

Query: 657 YMDFFPVPSN------------------------ASTDFLFEKSA-TYFDSEVVPRRGA- 690
           Y+D F + ++                        AS   +++ +A T+F           
Sbjct: 313 YLDLFDLAAHQIHQGLQASSAKEQSKMNTIIIGEASASTMWDNNAWTFFYDNSTDGEPPF 372

Query: 691 -------ALLPRAKIITVLTNPADRAYSWYQHQRAHGDPV---------ALNYTFYQVIS 734
                  A  P A++I +L +P +R YS Y +  +              AL      ++ 
Sbjct: 373 LTQDFIHAFQPNARLIVMLRDPVERLYSDYLYFASSNKSADDFHEKVTEALQLFENCMLD 432

Query: 735 ASSQTPLALRSLQNRC---LVPGYYSTHLQRWLTYYPSGQLLIVDGQELRTNPAASMESI 791
            S +  +   +L N     L  G Y+ +L  WL+ +   Q LI+  ++  +N   +M  +
Sbjct: 433 YSLRACVYNNTLNNAMPVRLQVGLYAVYLLDWLSVFDKQQFLILRLEDHASNVKYTMHKV 492

Query: 792 QKFLGITPFLNYTRTLRFDDDKGFWCQGLEGGKTRCLGRSKGRRYPDMDTESRLFLTDFF 851
            +FL + P          +  +    +       R   R+ G  +P     ++  L DF+
Sbjct: 493 FQFLNLGPL--------SEKQEALMTKSPASNARRPEDRNLGPMWP----ITQKILRDFY 540

Query: 852 RNHNLELSKLLS 863
           R  N  L+++L+
Sbjct: 541 RPFNARLAQVLA 552


>gi|122937321 UNC homeobox [Homo sapiens]
          Length = 531

 Score = 40.8 bits (94), Expect = 0.006
 Identities = 23/55 (41%), Positives = 24/55 (43%), Gaps = 14/55 (25%)

Query: 41  SPKAKEPLPLPL-------------GDCSSGGAAGPGPARPPVPPRP-PRPPETA 81
           SP A  P P P              GDC+  G AGP P  P   PRP PRPP  A
Sbjct: 449 SPGAPAPAPAPFRDLASAAATEGGGGDCADAGTAGPAPPPPAPSPRPGPRPPSPA 503


>gi|206597445 alpha 1 type XVIII collagen isoform 3 precursor [Homo
            sapiens]
          Length = 1751

 Score = 39.7 bits (91), Expect = 0.012
 Identities = 22/51 (43%), Positives = 24/51 (47%), Gaps = 1/51 (1%)

Query: 29   GSMGFLAYYVSTSPKAKEPLPLPLGDCSSGGAAG-PGPARPPVPPRPPRPP 78
            G  G L    +   K  +  P P G     G AG PGPA PP PP PP PP
Sbjct: 968  GQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPP 1018



 Score = 30.0 bits (66), Expect = 9.9
 Identities = 16/45 (35%), Positives = 19/45 (42%), Gaps = 8/45 (17%)

Query: 42   PKAKEPLPLPLGDCSSGGAAGPGPARPP--------VPPRPPRPP 78
            P+    +P P G+   G    PGP  PP         PP PP PP
Sbjct: 1361 PRGYPGIPGPKGESIRGQPGPPGPQGPPGIGYEGRQGPPGPPGPP 1405


>gi|110611233 alpha 1 type XVIII collagen isoform 2 precursor [Homo
           sapiens]
          Length = 1336

 Score = 39.7 bits (91), Expect = 0.012
 Identities = 22/51 (43%), Positives = 24/51 (47%), Gaps = 1/51 (1%)

Query: 29  GSMGFLAYYVSTSPKAKEPLPLPLGDCSSGGAAG-PGPARPPVPPRPPRPP 78
           G  G L    +   K  +  P P G     G AG PGPA PP PP PP PP
Sbjct: 553 GQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPP 603



 Score = 30.0 bits (66), Expect = 9.9
 Identities = 16/45 (35%), Positives = 19/45 (42%), Gaps = 8/45 (17%)

Query: 42  PKAKEPLPLPLGDCSSGGAAGPGPARPP--------VPPRPPRPP 78
           P+    +P P G+   G    PGP  PP         PP PP PP
Sbjct: 946 PRGYPGIPGPKGESIRGQPGPPGPQGPPGIGYEGRQGPPGPPGPP 990


>gi|110611235 alpha 1 type XVIII collagen isoform 1 precursor [Homo
           sapiens]
          Length = 1516

 Score = 39.7 bits (91), Expect = 0.012
 Identities = 22/51 (43%), Positives = 24/51 (47%), Gaps = 1/51 (1%)

Query: 29  GSMGFLAYYVSTSPKAKEPLPLPLGDCSSGGAAG-PGPARPPVPPRPPRPP 78
           G  G L    +   K  +  P P G     G AG PGPA PP PP PP PP
Sbjct: 733 GQKGSLGEAGAPGHKGSKGAPGPAGARGESGLAGAPGPAGPPGPPGPPGPP 783



 Score = 30.0 bits (66), Expect = 9.9
 Identities = 16/45 (35%), Positives = 19/45 (42%), Gaps = 8/45 (17%)

Query: 42   PKAKEPLPLPLGDCSSGGAAGPGPARPP--------VPPRPPRPP 78
            P+    +P P G+   G    PGP  PP         PP PP PP
Sbjct: 1126 PRGYPGIPGPKGESIRGQPGPPGPQGPPGIGYEGRQGPPGPPGPP 1170


>gi|46909600 a disintegrin and metalloproteinase domain 15 isoform 6
           preproprotein [Homo sapiens]
          Length = 863

 Score = 39.3 bits (90), Expect = 0.016
 Identities = 21/42 (50%), Positives = 23/42 (54%), Gaps = 3/42 (7%)

Query: 42  PKAKEPLPL-PLGDCSSGGAAGPGPARPP--VPPRPPRPPET 80
           P  ++PLP  P G C SG   GPG   PP  VP RP  PP T
Sbjct: 816 PPPRKPLPADPQGRCPSGDLPGPGAGIPPLVVPSRPAPPPPT 857


>gi|46909598 a disintegrin and metalloproteinase domain 15 isoform 5
           preproprotein [Homo sapiens]
          Length = 862

 Score = 39.3 bits (90), Expect = 0.016
 Identities = 21/42 (50%), Positives = 23/42 (54%), Gaps = 3/42 (7%)

Query: 42  PKAKEPLPL-PLGDCSSGGAAGPGPARPP--VPPRPPRPPET 80
           P  ++PLP  P G C SG   GPG   PP  VP RP  PP T
Sbjct: 815 PPPRKPLPADPQGRCPSGDLPGPGAGIPPLVVPSRPAPPPPT 856


>gi|46909596 a disintegrin and metalloproteinase domain 15 isoform 4
           preproprotein [Homo sapiens]
          Length = 838

 Score = 39.3 bits (90), Expect = 0.016
 Identities = 21/42 (50%), Positives = 23/42 (54%), Gaps = 3/42 (7%)

Query: 42  PKAKEPLPL-PLGDCSSGGAAGPGPARPP--VPPRPPRPPET 80
           P  ++PLP  P G C SG   GPG   PP  VP RP  PP T
Sbjct: 791 PPPRKPLPADPQGRCPSGDLPGPGAGIPPLVVPSRPAPPPPT 832


>gi|46909594 a disintegrin and metalloproteinase domain 15 isoform 3
           preproprotein [Homo sapiens]
          Length = 839

 Score = 39.3 bits (90), Expect = 0.016
 Identities = 21/42 (50%), Positives = 23/42 (54%), Gaps = 3/42 (7%)

Query: 42  PKAKEPLPL-PLGDCSSGGAAGPGPARPP--VPPRPPRPPET 80
           P  ++PLP  P G C SG   GPG   PP  VP RP  PP T
Sbjct: 792 PPPRKPLPADPQGRCPSGDLPGPGAGIPPLVVPSRPAPPPPT 833


>gi|46909590 a disintegrin and metalloproteinase domain 15 isoform 2
           preproprotein [Homo sapiens]
          Length = 814

 Score = 39.3 bits (90), Expect = 0.016
 Identities = 21/42 (50%), Positives = 23/42 (54%), Gaps = 3/42 (7%)

Query: 42  PKAKEPLPL-PLGDCSSGGAAGPGPARPP--VPPRPPRPPET 80
           P  ++PLP  P G C SG   GPG   PP  VP RP  PP T
Sbjct: 767 PPPRKPLPADPQGRCPSGDLPGPGAGIPPLVVPSRPAPPPPT 808


>gi|45935385 SAM and SH3 domain containing 1 [Homo sapiens]
          Length = 1247

 Score = 38.1 bits (87), Expect = 0.036
 Identities = 19/51 (37%), Positives = 25/51 (49%)

Query: 59  GAAGPGPARPPVPPRPPRPPETARTEPVVLVFVESAYSQLGQEIVAILESS 109
           GAAGPGP   P P   P P      EP        A+S+L  +++ IL+ S
Sbjct: 5   GAAGPGPEPEPEPEPEPEPAPEPEPEPKPGAGTSEAFSRLWTDVMGILDGS 55


>gi|21389567 chemokine-like factor superfamily 2 [Homo sapiens]
          Length = 248

 Score = 37.4 bits (85), Expect = 0.062
 Identities = 23/76 (30%), Positives = 37/76 (48%), Gaps = 6/76 (7%)

Query: 8   VRPARQLELHRLILLLIAFSLGSMGFLAYYVSTS----PKAKEPLPLPLGDCSSGG--AA 61
           VR  R + LH L+ +++  + G   F+   +  +     KAK+ + +P      G     
Sbjct: 168 VRSRRSMNLHYLLAVILIGAAGVFAFIDVCLQRNHFRGKKAKKHMLVPPPGKEKGPQQGK 227

Query: 62  GPGPARPPVPPRPPRP 77
           GP PA+PP P +PP P
Sbjct: 228 GPEPAKPPEPGKPPGP 243


>gi|38194229 kelch-like 17 [Homo sapiens]
          Length = 642

 Score = 37.4 bits (85), Expect = 0.062
 Identities = 15/27 (55%), Positives = 16/27 (59%)

Query: 59 GAAGPGPARPPVPPRPPRPPETARTEP 85
          G+ GPGP  PP PP  P  PE  RT P
Sbjct: 18 GSPGPGPEAPPPPPPQPPAPEAERTRP 44


>gi|56847626 sulfotransferase family, cytosolic, 1C, member 3 [Homo
           sapiens]
          Length = 304

 Score = 35.8 bits (81), Expect = 0.18
 Identities = 46/214 (21%), Positives = 83/214 (38%), Gaps = 35/214 (16%)

Query: 591 KDIWSKEKTCDRLPKFLIVGPQ-KTGTTAIHFFLSLHPAVTSSFPSPSTFEEIQFFNSPN 649
           K+ W K       P  LI+    K+GTT +H  L +         +    E+ +   + +
Sbjct: 33  KEWWEKVCNFQAKPDDLILATYPKSGTTWMHEILDM-------ILNDGDVEKCKRAQTLD 85

Query: 650 YHKGIDWYMDFFPVPSNASTDFLFEKSA-----TYFDSEVVPRRGAALLPRAKIITVLTN 704
            H  ++     FP       +F+ E S+     T+  S ++P   +      KI+ V  N
Sbjct: 86  RHAFLELK---FPHKEKPDLEFVLEMSSPQLIKTHLPSHLIPP--SIWKENCKIVYVARN 140

Query: 705 PADRAYSWYQHQRAHG---DPVALNYTFYQVISASSQTPLALRSLQNRCLVPGYYSTHLQ 761
           P D   S+Y   R      DP  L   + + +S                +V G +  H++
Sbjct: 141 PKDCLVSYYHFHRMASFMPDPQNLEEFYEKFMSGK--------------VVGGSWFDHVK 186

Query: 762 RWLTYYPSGQLLIVDGQELRTNPAASMESIQKFL 795
            W       ++L +  ++++ +P   +E I KFL
Sbjct: 187 GWWAAKDMHRILYLFYEDIKKDPKREIEKILKFL 220


>gi|157649073 adenylyl cyclase-associated protein [Homo sapiens]
          Length = 475

 Score = 35.4 bits (80), Expect = 0.24
 Identities = 21/39 (53%), Positives = 22/39 (56%), Gaps = 7/39 (17%)

Query: 40  TSPKAKEPLPLPLGDCSSGGAAGPGPARPPVPPRPPRPP 78
           T P AKE   LP     SG +AG GP  PP PP PP PP
Sbjct: 210 TGPVAKELSGLP-----SGPSAGSGP--PPPPPGPPPPP 241


>gi|5453595 adenylyl cyclase-associated protein [Homo sapiens]
          Length = 475

 Score = 35.4 bits (80), Expect = 0.24
 Identities = 21/39 (53%), Positives = 22/39 (56%), Gaps = 7/39 (17%)

Query: 40  TSPKAKEPLPLPLGDCSSGGAAGPGPARPPVPPRPPRPP 78
           T P AKE   LP     SG +AG GP  PP PP PP PP
Sbjct: 210 TGPVAKELSGLP-----SGPSAGSGP--PPPPPGPPPPP 241


>gi|170650694 centaurin, gamma 1 isoform PIKE-L [Homo sapiens]
          Length = 1192

 Score = 35.0 bits (79), Expect = 0.31
 Identities = 40/153 (26%), Positives = 63/153 (41%), Gaps = 17/153 (11%)

Query: 39  STSPKAKEPLPLPLGDCSSGGAAGPGPARPPVPPRPPRPPETARTEPVVLVFVESAYSQL 98
           S  P    P P P    ++  A  PGPA PP+   PP P      E           S  
Sbjct: 289 SPPPLTLPPTPSPATAVTAASAQPPGPA-PPITLEPPAPGLKRGRE-------GGRASTR 340

Query: 99  GQEIVAILESSRFRYSTELAPGRGDM---PTLTDNTHGRYVL--VIYENLLKYVNLDAWS 153
            ++++  + S  F  ST   PG G +   P+L+  +  R +L   +  +    +N   W+
Sbjct: 341 DRKMLKFI-SGIFTKSTGGPPGSGPLPGPPSLSSGSGSRELLGAELRASPKAVINSQEWT 399

Query: 154 RELLDRYCVEYGVGIIGFFRAHEHSLLSAQLKG 186
              L R   E  +G++G  R+ + SL+   L G
Sbjct: 400 ---LSRSIPELRLGVLGDARSGKSSLIHRFLTG 429


>gi|157168329 formin 1 [Homo sapiens]
          Length = 1196

 Score = 34.7 bits (78), Expect = 0.40
 Identities = 16/32 (50%), Positives = 17/32 (53%)

Query: 47  PLPLPLGDCSSGGAAGPGPARPPVPPRPPRPP 78
           PLP  LG  S      P  A PP+PP PP PP
Sbjct: 657 PLPSGLGSLSPAPPMPPVSAGPPLPPPPPPPP 688



 Score = 31.6 bits (70), Expect = 3.4
 Identities = 18/45 (40%), Positives = 20/45 (44%), Gaps = 2/45 (4%)

Query: 42  PKAKEPLPLPLGDCSSGGAAGPGPARPPVPPRPPRPPETARTEPV 86
           P A  P P PL   S  G+  P P  PPV   PP PP      P+
Sbjct: 648 PPASIPPPPPLP--SGLGSLSPAPPMPPVSAGPPLPPPPPPPPPL 690


>gi|10863899 numb homolog (Drosophila)-like [Homo sapiens]
          Length = 609

 Score = 34.7 bits (78), Expect = 0.40
 Identities = 16/30 (53%), Positives = 17/30 (56%)

Query: 56 SSGGAAGPGPARPPVPPRPPRPPETARTEP 85
          +SGG   P    PP P   P PPET RTEP
Sbjct: 7  ASGGPRRPERHLPPAPCGAPGPPETCRTEP 36


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.323    0.140    0.444 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 38,545,144
Number of Sequences: 37866
Number of extensions: 2021596
Number of successful extensions: 15109
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 86
Number of HSP's successfully gapped in prelim test: 142
Number of HSP's that attempted gapping in prelim test: 13085
Number of HSP's gapped (non-prelim): 1660
length of query: 883
length of database: 18,247,518
effective HSP length: 111
effective length of query: 772
effective length of database: 14,044,392
effective search space: 10842270624
effective search space used: 10842270624
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.